cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Multiscale Approach for the Design of Composite Sandwich Elements
Creators: name: Zinno, Alberto
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2010

description: In the present work, composite sandwich components, that perfectly match the challenging demands of lightweight and more customized structures, have been characterized and designed as a roof panels of a railway vehicle.
The most critical issue related to the design and assessment of composite sandwich structures are discussed and analyzed in a multiscale procedure.
A multiscale procedure has been developed using knowledge-based procedure for the optimal stiffness design of composite sandwich structures under some classified design rules. Recent developments of multifunctional design tools, integrating structural and functional features, enables a next step toward the exploitation of the composite sandwich benefits in a wide range of applications
In particular new phenolic impregnated composite skins have been characterized and involved in sandwich configuration for load carrying components. The selected composite materials have been analyzed with different core configuration and the use of both numerical and analytical tools have been assessed with particular attentions to various failure mode that can be expected..
However, the use of fiber reinforced composite materials presents a significant challenge with respect to the methods of joining to be used in body fabrication. At this aim the project provides the characterization of potential joining techniques available to the railway industry involving both composite and aluminum components. Problems related to strength and durability of the joints have been experimentally characterized.
The durability of composites, in addition to being dependent on loading conditions, is strongly dependent on the environmental conditions, in terms of the specific combinations of temperature, relative humidity, exposure to electro-magnetic radiation, to solvents, acid and alkaline conditions and of their (cyclic) evolution during time. Since the degradation process of a composite sandwich structure depends on the environmental conditions, type of skins and core material, and production process, mechanical properties through accelerated ageing tests have been performed in order to predict long-term performances of sandwich composites and to determine the correlation between mechanical damage and aging due to different environmental factors..
In addition to the aforementioned issues, in order to reliably predict the structural safety of composite sandwich structures, understanding the adverse effect of in-service impact events (e.g. impact and penetration damage) has become important in the transportation industry. Both quasi static and dynamic impact have been experimentally analyzed in the present study and the damage mechanism have been related to the type of impact events.
Finally optimization and validation of the designed sandwich structures have been performed by means of finite element simulation.
Development of Kytoon Station
for Meteorological and Air Pollution Measurements in a Mediterranean Urban Climate
Creators: name: Panelli, Mario
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2010

description: La conoscenza di profili verticali dei parametri meteo e d’inquinanti e delle loro caratteristiche (statistiche, spettri cross-correlazioni dei parametri) sono cruciali nella comprensione dei meccanismi di dispersione degli inquinanti in presenza di un microclima tipico delle città mediterranee che è caratterizzato dalla presenza contemporanea dei venti di brezza (mare/terra), delle correnti di valle (anabatiche/catabatiche) e d’isole urbane di calore. Il lavoro di tesi si è focalizzato sullo sviluppo di una stazione multi-parametrica del tipo Kytoon (costituita da un aerostato e dalla stazione di rilevamento, sospesa sotto di esso, vincolati al suolo per mezzo di un cavo). Inoltre il sistema di lancio/recupero del pallone è stato realizzato su un carrello appendice al fine di consentire un agevole trasporto di tutto il sistema e quindi la possibilità di eseguire facilmente lanci da punti geografici diversi. I parametri misurati dalla stazione meteo realizzata sono: modulo e direzione della velocità del vento, pressione atmosferica, temperatura, umidità, e le concentrazioni di quattro sostanze, ritenute dalla normativa europea, pericolose per l’ambiente e per l’uomo, cioè 03, CO, C6H6, NO2.  La kytoon station in oggetto permette di misurare i parametri prima elencati con elevata risoluzione temporale (32Hz) permettendo la misura dei profili verticali delle principali grandezze statistiche turbolente (medie, energia cinetica turbolenta, varianze, spettro); di stimare profili verticali delle temperature potenziali individuando le eventuali condizioni d’instabilità atmosferiche (Numero di Richardson); di valutare le cross correlazioni tra il vento (modulo e direzione) e le concentrazioni dei citati inquinanti. In tal senso il lavoro è del tutto originale poiché nella letteratura scientifica sono presenti solo studi della turbolenza atmosferica in ambiente urbano, basate sull’uso di torri meteorologiche (che presentano una quota limitata), con frequenze di acquisizioni limitate e senza contemporanei rilevamenti di sostanze inquinanti. Al fine di ottenere da parte di E.N.A.C. ed E.N.A.V. il rilascio di un NOTAM per il lancio del pallone aerostatico in area urbana é stato necessario eseguire un’analisi della probabilità di guasto di tutti i sottosistemi per le varie condizioni operative e la Functional Hazard Assessment dell’intero sistema.  Dal 7 al 17/9/2010 è stata infine realizzata una campagna di misure nei pressi della reggia di Caserta con la quale si sono potute evidenziare le grandi potenzialità di analisi dei fenomeni atmosferici dell’attrezzatura realizzata.
Le relazioni finanziarie tra banca e industria
Creators: name: Petrillo, Maria Rosaria
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2010

description: Il problema del rapporto tra banca e industria va considerato sotto due distinti profili: quello delle partecipazioni bancarie nell'industria e quello delle partecipazioni delle imprese nel capitale bancario.
Climate change and cocoa flavour quality: analytical investigations to identify off-odour in cocoa products
Creators: name: Liberto, Erica
name: Cordero, Chiara
name: Perotti, Pamela
name: Bortolini, Cristian
name: Bicchi, Carlo
Publisher: name: Zenodo
Year: 2021
Subjects: Cocoa volatilome
smoky off-flavour
GCxGC-TOF-MS
HS-SPME-GC-MS
MS-enose

description: Cocoa smoky off-flavour is due to inappropriate post-harvest processing and cannot be removed in the subsequent chocolate-manufacturing steps. To date, no reliable analytical method to detect key-analytes responsible for smoky off-flavour in incoming raw material is available and the sensory tests are time-consuming. This study aims to develop an analytical method to detect smoky markers, suitable for quality control. A top-down procedure was applied: the cocoa volatilome was first profiled by headspace solid phase microextration (HS-SPME) combined with comprehensive two-dimensional gas chromatography-mass spectrometry (GCxGC-TOF-MS) from a set of representative smoky and non-smoky samples; advanced fingerprinting revealed the chemicals responsible for the off-flavour. The results served to develop a 1D-GC method suitable for routine application. Ten identified smoky markers were subjected to accurate quantification, thereby defining operative ranges to accept/reject incoming bean samples. A step ahead was devoted to automatically speeding up the controls through a MS-enose platform coupled with suitable chemometric modelling to classify smoky and non-smoky samples and cross-validated by the confirmatory quantitative method through HS-SPME-GC-MS. Thus, it was successfully developed an objective and automatic analytical decision maker suitable for the control at multistep level on the chocolate production chain.
CMOL: Second Life for Silicon?
Creators: name: Likharev, K. -K.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: This report is a brief review of the recent work on architectures for the prospective hybrid CMOS/nanowire/ nanodevice ("CMOL") circuits including digital memories, reconfigurable Boolean-logic circuits, and mixed-signal neuromorphic networks. The basic idea of CMOL circuits is to combine the advantages of CMOS technology (including its flexibility and high fabrication yield) with the extremely high potential density of molecular-scale two-terminal nanodevices. Relatively large critical dimensions of CMOS components and the "bottom-up" approach to nanodevice fabrication may keep CMOL fabrication costs at affordable level. At the same time, the density of active devices in CMOL circuits may be as high as 1012 cm2 and that they may provide an unparalleled information processing performance, up to 1020 operations per cm2 per second, at manageable power consumption.
description: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions)
VALUTAZIONE DELLA FUNZIONE CARDIACA NEI PAZIENTI PEDIATRICI CON TRAPIANTO CARDIACO: UNO STUDIO ECOCARDIOGRAFICO CON ECOCARDIOGRAFIA SPECKLE TRACKING ED ECOCARDIOGRAFIA TRIDIMENSIONALE
Creators: name: Esposito, Claudia
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2011

description: La valutazione della funzione cardiaca è di importanza fondamentale nei pazienti con trapianto cardiaco. Abbiamo analizzato 60 pazienti pediatrici sottoposti a trapianto cardiaco e 30 volontari sani con simile distribuzione di eta’ e sesso. I pazienti sono stati sottoposti a studio ecocardiografico transtoracico completo di metodica speckle tracking bidimensionale ed ecografia tridimensionale per lo studio della sincronia ventricolare. I nostri risultati suggeriscono che la funzione sistolica del ventricolo trapiantato e’ significativamente diversa rispetto a quella del cuore normale. L’analisi con speckle tracking ed ecografia tridimensionale permette di identificare tali differenze, caratterizzate da una significativa dissincronia sistolica, una riduzione della funzione contrattile longitudinale biventricolare, ed una conseguente alterazione della torsion ventricolare.
INTERCULTURAL CONTACT, COMPETENCE, AND CONVIVIALITY: A PROPOSAL FOR CAMPUS ENGAGEMENT AND BELONGING
Creators: name: Buntain, Leighton A
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: subject: 139999 Education not elsewhere classified
subject: FOS: Educational sciences
subject: 200101 Communication Studies
subject: FOS: Media and communications
subject: 200299 Cultural Studies not elsewhere classified
subject: FOS: Other humanities
subject: 200206 Globalisation and Culture
subject: 130103 Higher Education

description: International education is big business and international students are a large minority on many of the U.S.’s most reputable institutions. However, a persistent issue has been the tendency for international and U.S. domestic students to socialize largely within their own groups of co-nationals. Utilizing a paradigmatic case study approach on a large public university, this dissertation consists of three separate, but connected, studies that feature, respectively, (1) staff and faculty intercultural learning and contact, (2) undergraduate student experiences of intercultural contact and friendship, and (3) undergraduate student assessments of campus spaces and programs for interacting across culture. These studies integrated frameworks from intercultural competence, intergroup contact theory, and conviviality. Findings throughout the case study confirmed that friendship and contact between international and domestic U.S. individuals was limited, even when the participants were motivated, experienced, and demonstrated many aspects of intercultural competence. Further, the case was characterized by administrative efforts to address the issue through formal classes, workshops, and festivals, while generally overlooking the informal spaces that students found most integral to their own experiences. These findings underscore a disconnect between trying to “prepare” individuals for contact rather than attempting to “create” the spaces and programs for such contact to occur, i.e., a focus on the individual’s knowledge and skills rather than the interpersonal and environmental conditions in contact. The findings culminated in the proposed Programmatic Conviviality Model, qualities which are theorized to support convivial intercultural contact. I argue that this model and the realignment to a focus on intercultural contact as a goal, is necessary for college campuses beyond the immediate case study and that this work is timely as campuses move back to in-person engagement after almost two years of COVID isolation.
CLINICAL FEATURES, DIAGNOSIS AND TREATMENT OF CHRONIC CYSTITIS IN CHILDREN
Creators: name: Azizov, Ulug'bek
name: Muxammadov, Shaxriddin
name: Jurayeva, Barno
Publisher: name: Zenodo
Year: 2023

description: Chronic cystitis in children is a persistent inflammatory condition of the urinary bladder that poses unique challenges in diagnosis and management. This article comprehensively reviews the clinical features, diagnostic strategies, and treatment modalities for chronic cystitis in pediatric patients. The objective is to provide healthcare professionals with a deeper understanding of this condition, aiding in early identification and effective intervention to improve the quality of life for affected children. Chronic cystitis, a persistent inflammation of the bladder, poses a significant health concern in pediatric populations. While acute cystitis is a common occurrence in children, chronic cystitis represents a more enduring and challenging condition that can adversely impact the quality of life and long-term health of affected individuals. This article aims to comprehensively review the clinical features, diagnostic approaches, and treatment modalities of chronic cystitis in children, shedding light on the complexities associated with this condition.
Molecular Electronics: Effect of external electric field
Creators: name: Lakshmi, S.
name: Dutta, Sudipta
name: Pati, Swapan K.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The effect of electric field, applied on systems in the nanoscale regime has attracted a lot of research in recent times. We highlight some of the recent results in the field of single molecule electronics and then move on to focus on some of our own results in this area. We have first shown how important it is to obtain the spatial profile of the external bias potential across the system, and how this would change in the presence of electron-electron interactions. We have also studied different kinds of insulators in the presence of the spatially varying external bias, and have explicitly shown that a two sublattice structure, caused either by a lattice distortion, or by the presence of substituents with strong dipolar nature, can result in negative differential resistance (NDR) in the transport characteristics. We also find this to be true in case of correlated insulators. Additionally, we have shown clear NDR behavior in a correlated double quantum dot by tuning the electron-electron interaction strength in the system.
description: 53 pages, 15 figures, accepted for publication in Journal of Physical Chemistry C as a feature article
Hamiltonian reductions of free particles under polar actions of compact Lie groups
Creators: name: Feher, L.
name: Pusztai, B. G.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Classical and quantum Hamiltonian reductions of free geodesic systems of complete Riemannian manifolds are investigated. The reduced systems are described under the assumption that the underlying compact symmetry group acts in a polar manner in the sense that there exist regularly embedded, closed, connected submanifolds meeting all orbits orthogonally in the configuration space. Hyperpolar actions on Lie groups and on symmetric spaces lead to families of integrable systems of spin Calogero-Sutherland type.
description: 15 pages, minor correction and updated references in v2
Bottom-Up Approach to Silicon Nanoelectronics
Creators: name: Mizumita, Hiroshi
name: Oda, S.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: This paper presents a brief review of our recent work investigating a novel bottom-up approach to realize silicon based nanoelectronics. We discuss fabrication technique, electronic properties and device applications of silicon nanodots as a building block for nanoscale silicon devices.
description: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions)
From Deterministic Chaos to Anomalous Diffusion
Creators: name: Klages, R.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: This is an easy-to-read introduction to foundations of deterministic chaos, deterministic diffusion and anomalous diffusion. The first part introduces to deterministic chaos in one-dimensional maps in form of Ljapunov exponents and dynamical entropies. The second part outlines the concept of deterministic diffusion. Then the escape rate formalism for deterministic diffusion, which expresses the diffusion coefficient in terms of the above two chaos quantities, is worked out for a simple map. Part three explains basics of anomalous diffusion by demonstrating the stochastic approach of continuous time random walk theory for an intermittent map. As an example of experimental applications, the anomalous dynamics of biological cell migration is discussed.
description: 49 pages, 20 figures; previous lecture notes extended by a new third chapter on anomalous diffusion; to be published in Reviews of Nonlinear Dynamics and Complexity, Vol.3, as a book chapter
“Synthesis, characterization and applications of metal organic frameworks in the energy industry field”
Creators: name: Imperatore, Maria
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2011

description: Il Progetto di Ricerca legato a questo lavoro di tesi ha avuto come obiettivo principale la individuazione di materiali innovativi per l'adsorbimento e stoccaggio di gas a fini energetici. In particolare l'attività di ricerca ha riguardato lo studio di materiali adsorbenti microporosi, inorganici (zeolite-type) e metallo-organici (metal organic frameworks, MOF), mediante metodologie sperimentali e di modellazione. Gli obiettivi specifici dell'attività sperimentale relativa alla ricerca sui materiali sono di seguito elencati.
1. Messa a punto di protocolli di sintesi e modificazione di materiali microporosi di nuova generazione sia con struttura inorganica (zeo-type) che metallo-organica (MOF).
2. Caratterizzazione strutturale dei materiali adsorbenti (dopo sintesi e/o modificazione) mediante microscopia a scansione elettronica (SEM) analisi diffrattometrica
a raggi X su polveri (PXRD), analisi termica (DTA e DSC) ed analisi porosimetrica. L'analisi porosimetrica, in particolare, ha consentito di valutare l'area
superficiale specifica e il volume dei micropori, parametri da quali in larga misura dipende la capacità di adsorbimento dei materiali in questione.
3. Valutazione e modellazione delle proprietà di adsorbimento e stoccaggio di gas attraverso prove sperimentali di laboratorio.
Fundamental Building Blocks for The Design of A Single-electron Nanoelectronic Processor
Creators: name: Zardalidis, G.
name: Karafyllidis, I.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: A single-electron random access memory array (RAM) and a single-electron universal Fredkin gate are designed and simulated. The universality of the Fredkin gate in combination with the RAM gives the potential of the realization of an elementary single-electron nanoelectronic processor.
description: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions)
How to Build Trust in Science? Let's build trust in science! Recommendations from the VERITY Project
Creators: name: Gurzawska, Agata
name: Evren, Yalaz
Publisher: name: Zenodo
Year: 2024

description: The project

The VERITY project, a collaborative endeavour aimed at reshaping the ecosystem of trust in science through various innovative approaches and methodologies, is funded by the European Union under Grant agreement ID 101058623. Trilateral Research, EUREC, F6S, Zentrum Fur Soziale Innovation, UCLAN Cyprus, and Panepistimio Dytikis Attikis integrate the VERITY consortium.

The poster

This VERITY project poster, presented by Dr Agata Gurzawska and Dr Evren Yalaz from Trilateral Research at the 8th World Conference on Research Integrity held from June 2 to 5, 2024, in Athens, Greece, provides comprehensive insights and recommendations from the VERITY Project on how to build and sustain trust in science.

The poster outlines developing and validating a protocol of recommendations for "Stewards of Trust" to enhance trust in science. The concept of an "Ecosystem of trust" in science is introduced, highlighting the complex interactions and factors that influence societal trust. Key strategies to strengthen this ecosystem include:

Fostering collaboration between science and society,

Co-creating methods and tools to guide societal trust, and,

Exploring the sources and consequences of mistrust in science.

Moreover, the poster underlines the crucial need for involving diverse stakeholders, including companies, influencers, and underrepresented groups, to expand trust in science.
Additional file 5: of HyPRP1 performs a role in negatively regulating cotton resistance to V. dahliae via the thickening of cell walls and ROS accumulation
Creators: name: Yang, Jun
name: Zhang, Yan
name: Wang, Xingfen
name: Wang, Weiqiao
name: Li, Zhikun
name: Wu, Jinhua
name: Wang, Guoning
name: Wu, Liqiang
name: Zhang, Guiyin
name: Ma, Zhiying
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Table S1. Primers used in this study. (DOCX 15â kb)
On Exchangeable Continuous Variable Systems
Creators: name: Koenig, Robert
name: Wolf, Michael M.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate permutation-invariant continuous variable quantum states and their covariance matrices. We provide a complete characterization of the latter with respect to permutation-invariance, exchangeability and representing convex combinations of tensor power states. On the level of the respective density operators this leads to necessary criteria for all these properties which become necessary and sufficient for Gaussian states. For these we use the derived results to provide de Finetti-type theorems for various distance measures.
description: 4 pages
Microfluidics assisted platforms for biotechnological applications
Creators: name: Orabona, Emanuele
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2011

description: The aim of this PhD work is to exploit microfluidics features to improve the performances of some lab-on-a-chip designed for biotechnological applications: microfabrication techniques developed in the frame of telecommunication systems have by far found many other fields of applications, in particular optical sensing of chemical substances. The experience developed in design, fabricate, and test optical components or MEMS systems, can be successfully applied to the realization of lab-on-a-chip for specific scopes: two kind of microfluidics circuits for biotechnology have been considered, one integrated with the microarray technology, and the other devoted to cell manipulation.
Using Multi-Threshold Threshold Gates in RTD-based Logic Design. A Case Study
Creators: name: Pettenghi, H.
name: Avedillo, M. -J.
name: Quintana, J. -M.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: The basic building blocks for Resonant Tunnelling Diode (RTD) logic circuits are Threshold Gates (TGs) instead of the conventional Boolean gates (AND, OR, NAND, NOR) due to the fact that, when designing with RTDs, threshold gates can be implemented as efficiently as conventional ones, but realize more complex functions. Recently, RTD structures implementing Multi-Threshold Threshold Gates (MTTGs) have been proposed which further increase the functionality of the original TGs while maintaining their operating principle and allowing also the implementation of nanopipelining at the gate level. This paper describes the design of n-bit adders using these MTTGs. A comparison with a design based on TGs is carried out showing advantages in terms of latency, device counts and power consumption.
description: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions)
Microbial life and metabolism in Mediterranean Sea extreme environments
Creators: name: Giovannelli, Donato
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2013

description: The Mediterranean Sea is one of the most intensively investigated areas of the world. Despite this, it lags other regions of the world in studies of its deep sea and extreme environments. The contribution of Mediterranean extreme environments to global and regional diversity and biogeochemical cycles is poorly understood. Prokaryotes are the major component of Earth biodiversity, they outnumber any other living form and posses the greatest metabolic plasticity. This is especially true in extreme environments, where prokaryotes often constitute the only life form and play a key role in the functioning of those systems. Aim of this thesis is to investigate the diversity and role of prokaryotes in Mediterranean Sea extreme environment. The samples analyzed in this work were obtained in different oceanographic cruises and field trip around the Mediterranean Sea and are representatives of low- and high-energy environments. The used approach is a mix of traditional microbiology and ecology techniques combined with cutting-the-edge molecular tools, integrating laboratory and field survey. I started investigating the community structure in shallow-water sub-surface sediments evidencing a shift in the prokaryotic community composition. Despite the high biopolymeric organic C amount, results showed the major importance of the environmental factors influencing the availability of inorganic electron donors/acceptors, suggesting that lithotrophy could be an important metabolic pathway in shallow sub-surface sediments. In deep sea surface sediments across the Mediterranean Sea, community structure was instead dominated by Bacteria, and major driving force were trophic variables and geographic position within the basin, suggesting that overlaying water masses play a critical role in shaping deep-sea benthic prokaryotic communities. Different factors controlled prokaryotes distribution in shallow-water hydrothermal vents and seeps. In shallow-water vents prokaryotes distribution was controlled by temperature gradients rather than trophic resources. In cold-seeps environments the major drivers were both the presence of hydrocarbons and organic matter. In both areas the diversity was high, with a community evenly dominated by chemoautotrophic and heterotrophic metabolic strategies. Finally, the results obtained in different environments are brought together and emerging trends are analyzed.
In the future, to gain a deeper understand of the diversity and functioning of extreme environments, we will need to integrate ecology, microbiology, geochemistry, oceanography and molecular biology and shift our scale of measuring, reasoning and interpreting the microbial world from “human” to “microbial”.
Additional file 1 of Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation
Creators: name: Jia, Zhuoxuan
name: Kang, Bijun
name: Cai, Yizuo
name: Chen, Chingyu
name: Yu, Zheyuan
name: Li, Wei
name: Zhang, Wenjie
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 1: Figure S1. The isolated primary chondrocytes confirmation. Figure S2. Capillary density in synovium. Figure S3. CEFFE did not show any effect on Raw 264.7 cells polarization without LPS + IFN-γ. Figure S4. The original data of SOD-2 western blot results and original images of western blot presented in Fig. 7B. Figure S5. The original data of COX-2 and iNOS western blot results and original images of western blot presented in Fig. 8F.
Основы управления стартапом в IT
Creators: name: Bocharov, Nick
Publisher: name: Zenodo
Year: 2021
Subjects: управление проектом, it, pm

description: Управление IT стартапом – одна из наиболее часто исследуемых тем. Чтобы грамотно организовать процессы, нужно подготовиться теоретически, выбрать метод для управления проектами, сервис для планирования и контроля задач https://blog.ganttpro.com/ru/sistemy-instrumenty-servisy-upravlenie-proektami, а также правильно подобрать команду.
Natural ligands of nuclear receptors. Isolation, design, synthesis, biochemical decodification and potential therapeutic applications.
Creators: name: Ummarino, Raffaella
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2013

description: Natural products have historically been a rich source of  lead compounds in drug discovery. The biochemical investigation of marine organisms, through the deep collaboration between chemists and pharmacologists, focused on searching of new biologically active compounds, is a central issue of this kind of studies.
My research work, described in this PhD thesis, has been developed in this research area and was addressed to the identification of new ligands of nuclear receptors, discovering potent and selective modulators of farnesoid-X-receptor (FXR) and pregnane-X-receptor (PXR), regulators of various processes including reproduction, development, and metabolism of xeno- and endobiotics.
First, analysis of the polar extract of the sponge Theonella swinhoei afforded two new sulfated sterols, solomonsterols (SA and SB), the first example of  marine PXR agonists. Both have been synthesized and characterized in animal models of inflammation. Administration of synthetic solomonsterol A effectively protects against development of clinical signs and symptoms of colitis; therefore SA holds promise in the treatment of inflammatory bowel deseases (IBDs).
To overcome a limitation of SA in clinical settings, a small library of SA derivatives has been designed and prepared. Indeed, SA could be absorbed from the GIT causing severe systemic side effects resulting from the activation of PXR in the liver. This study disclosed cholestan disulfate (Coldisolf) as a new, simplified agonist of PXR, currently in pharmacological evaluation on animal models of liver fibrosis induced by HIV infection.
Simultaneously, a wide family of 4-methylene steroids were isolated from the apolar extracts of  Theonella swinhoei. These marine steroids are endowed with a potent agonistic activity on PXR while antagonize the effects of natural ligands for FXR.
Among this rich family, we have identified theonellasterol as the first example of a sponge derived highly selective FXR antagonist demonstrating its pharmacological potential in the treatment of cholestasis. Using this compound as a novel FXR antagonist hit, we have prepared a series of semi-synthetic derivatives in order to gain insights into the structural requirements for exhibiting antagonistic activity. These molecules could be used for the pharmacological treatment of cholestasis but also in chemotherapy of carcinoma characterized by over-expression of FXR.
In summary, Nature continues to be one of the best sources not only of potential chemotherapeutic agents but also of lead compounds that could represent an inspiration for the discovery of new therapeutic strategies.
An extended hydrodynamics model for inertial confinement fusion hohlraums
Creators: name: Larroche, Olivier
Publisher: name: arXiv
Year: 2021
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In some inertial confinement fusion hohlraum designs, the inside plasma is not sufficiently collisional to be satisfactorily described by the Euler equations implemented in hydrodynamic simulation codes, particularly in converging regions of the expanding plasma flow. To better treat that situation, this paper presents an extended hydrodynamics model including higher moments of the particle velocity distribution function, together with physically justified closure assumptions and relaxation terms. A preliminary one-dimensional numerical implementation of the model is shown to give satisfactory results in a test case involving a high-velocity collision of two plasma flows. Paths to extend that model to three dimensions as needed for an actual hohlraum geometry are briefly discussed.
description: 21 pages, 7 figures
Multiplets Matter: The Electronic Structure of Rare-Earth Semiconductors and Semimetals
Creators: name: Pourovskii, Leonid V.
name: Delaney, Kris T.
name: Van de Walle, Chris G.
name: Spaldin, Nicola A.
name: Georges, Antoine
Publisher: name: arXiv
Year: 2008
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We demonstrate that a theoretical framework fully incorporating intra-atomic correlations and multiplet structure of the localized 4f states is required in order to capture the essential physics of rare-earth semiconductors and semimetals. We focus in particular on the rare-earth semimetal erbium arsenide (ErAs), for which effective one-electron approaches fail to provide a consistent picture of both high and low-energy electronic states. We treat the many-body states of the Er 4f shell within an atomic approximation in the framework of dynamical mean-field theory. Our results for the magnetic-field dependence of the 4f local moment, the influence of multiplets on the photoemission spectrum, and the exchange splitting of the Fermi surface pockets as measured from Shubnikov-de Haas oscillations, are found to be in good agreement with experimental results.
description: 5 pages, 3 figures, 2 tables
Additional file 2 of Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation
Creators: name: Jia, Zhuoxuan
name: Kang, Bijun
name: Cai, Yizuo
name: Chen, Chingyu
name: Yu, Zheyuan
name: Li, Wei
name: Zhang, Wenjie
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 2: Table S1. Gene primers used in the article.
EXPRESSION OF OBJECT-EXPLANATORY RELATIONS IN A COMPLEX SENTENCE.
Creators: name: Xaydarova, Momokiz
Publisher: name: Zenodo
Year: 2023

description: This scientific article explores the intricate nature of expressing object-explanatory relations within the framework of complex sentences. The study investigates how language structures convey relationships between objects and explanations, shedding light on the syntactic and semantic nuances involved in the process. Through a comprehensive analysis of linguistic data and theoretical frameworks, the article aims to contribute to our understanding of how complex sentences serve as a medium for elucidating object-explanatory relations in diverse contexts.
Einstein hypersurfaces of Damek-Ricci spaces
Creators: name: Kim, Sinhwi
name: Nikolayevsky, Yuri
name: Park, JeongHyeong
Publisher: name: arXiv
Year: 2021
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C25 53C30 53B25 (Primary) 53C35 (Secondary)

description: Einstein hypersurfaces are ``very rare" in rank-one symmetric spaces. Damek-Ricci spaces may be viewed as the closest and the most natural generalisations of noncompact rank-one symmetric spaces. We prove that no Damek-Ricci space admits an Einstein hypersurface.
description: 14 pages
Development of guidelines for design of sampling programs to predict groundwater discharge
Creators: name: Cahn, Lorie Selma
Publisher: name: University of British Columbia
Year: 2010

description: The objective of this study is to develop guidelines for the design of sampling programs to predict groundwater discharge. A method for choosing a preferred sampling strategy from a set of alternatives is presented. A framework is outlined, in the form of an objective function, that incorporates both the cost of collecting data and the worth of data. A monetary value is assigned to the worth of hydraulic conductivity data by examining the economic losses associated with the uncertainty in predictions of groundwater discharge. The method is applied to the problem of designing a sampling program that measures hydraulic conductivity for predicting discharge from a rapid infiltration pond. Hydraulic conductivity data are generated for hypothetical hill slopes using a stochastic finite element model. A set of sampling strategies are selected. For each sampling strategy, the value and location of measurements and the uncertainty in the spatial variation of hydraulic conductivity are incorporated using conditional simulations. Estimates of pond discharge are calculated from the stream function solution and compared to the actual value of pond discharge for the hypothetical site. The root mean square error is used to quantify the uncertainty in discharge predictions. A set of alternative sampling strategies are compared using the objective function. Prediction uncertainty, measured by the root mean square error, is sensitive to both the structure of the heterogeneities and the location of measurements. Sampling schemes that lead to good estimates of the ensemble mean and standard deviation will not necessarily lead to good predictions of discharge. The goal of sampling schemes should be to collect data in key locations of the flow domain and to identify the spatial variation in hydraulic conductivity in a cost effective manner. For predicting discharge from a rapid infiltration pond, locating one or two initial boreholes below the pond is the preferred strategy for a majority of the cases tested. When the measurements are spaced evenly throughout the flow domain, important shallow layers may be missed that have a large influence on pond discharge. Increasing the number of boreholes does not necessarily lead to more certain predictions of pond discharge or to lower values of the objective function. Considerable uncertainty in discharge predictions can exist even with a relatively large number of measurements. While an optimal strategy exists, there is potential for significant variation in prediction uncertainty at individual sites.
The geography of Oxia Planum
Creators: name: Fawdon, Peter
name: Grindrod, Peter
name: Orgel, Csilla
name: Sefton-Nash, Elliot
name: Adeli, Solmaz
name: Balme, Matt
name: Cremonese, Gabriele
name: Davis, Joel
name: Frigeri, Alessandro
name: Hauber, Ernst
name: Le Deit, Laetitia
name: Loizeau, Damien
name: Nass, Andrea
name: Parks-Bowen, Adam
name: Quantin-Nataf, Cathy
name: Thomas, Nick
name: Vago, Jorge L.
name: Volat, Matthieu
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: We present the geography of Oxia Planum, the landing site for the ExoMars 2022 mission. This map provides the planetary science community with a framework to understand this, until recently, unexplored area. The map comprises (1) a mosaic of the panchromatic Context Camera (CTX) Digital Elevation Models (DEM) and Ortho Rectified Images (ORI) controlled to the High Resolution Stereo Camera (HRSC) multiorbit Digital Elevation Models (DEM) and (2) a mosaic of Colour and Stereo Surface Imaging System (CaSSIS) synthetic colour data products, registered to the CTX ORI mosaic. We define a grid of exploration quadrangles (quads) and an informal group of geographic regions to describe Oxia Planum. These regions bridge the scale gap between features observed on large areas (∼100s km2) and the local geography (10s km2) relevant to the Rosalind Franklin rover’s operations in Oxia Planum.
Shuffling algorithm for boxed plane partitions
Creators: name: Borodin, Alexei
name: Gorin, Vadim
Publisher: name: arXiv
Year: 2008
Subjects: subject: Combinatorics (math.CO)
subject: Mathematical Physics (math-ph)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We introduce discrete time Markov chains that preserve uniform measures on boxed plane partitions. Elementary Markov steps change the size of the box from (a x b x c) to ((a-1) x (b+1) x c) or ((a+1) x (b-1) x c). Algorithmic realization of each step involves O((a+b)c) operations. One application is an efficient perfect random sampling algorithm for uniformly distributed boxed plane partitions. Trajectories of our Markov chains can be viewed as random point configurations in the three-dimensional lattice. We compute the bulk limits of the correlation functions of the resulting random point process on suitable two-dimensional sections. The limiting correlation functions define a two-dimensional determinantal point processes with certain Gibbs properties.
description: 10 figures, 34 pages
Near-Field Linear Sampling Method forAxisymmetric Eddy Current Tomography
Creators: name: Haddar, H.
name: Riahi, M. K.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Numerical Analysis (math.NA)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: This paper is concerned with Eddy-Current (EC) nondestructive testing of conductive materials and focuses, in particular, on extending the well-known LinearSampling Method (LSM) to the case of EC equations. We first present the theoretical foundation of the LSM in the present context and in the case of point sources. We then explain how this method can be adapted to a realistic setting of EC probes. In the case of identifying the shape of external deposits from impedance measurements taken from inside of the tube (steam generator), we show how the method can be applied to measurements obtained from a sweeping set of coils. Numerical experiments suggest that good results can be achieved using only a few coils and even in the limiting case of backscattering data.
Eine Roadmap zur Entwicklung und Adaption von Methoden der Künstlichen Intelligenz (KI) für die Endlagerforschung
Creators: name: Krafczyk, Manfred
name: Brendler, Vinzenz
name: Czaikowski, Oliver
name: Gruner, Matthias
name: Hoth, Niels
name: Kolditz, Olaf
name: Nagel, Thomas
name: Herold, Philipp
name: Müller, Christian
name: Seher, Holger
name: Simo, Eric
name: Stahlmann, Joachim
Publisher: name: Zenodo
Year: 2021
Subjects: Künstliche Intelligenz, Endlagerforschung, Digitaler Zwilling, BIM, GIS, Virtualisierung

description: Methoden der Künstlichen Intelligenz (KI) haben insbesondere in der letzten Dekade wesentliche Beiträge zum wissenschaftlich-technischen Fortschritt geleistet. Das Potenzial von KI-Methoden zur Verbesserung der Prognose naturwissenschaftlicher und technologischer Aspekte bei der Standortauswahl sowie bei der Errichtung und (Nach-)Betriebsphase eines Endlagers (Endlagerentwicklung) wurde bisher jedoch nicht systematisch untersucht. Es wird daher empfohlen, im Rahmen von gezielten Forschungs- und Entwicklungsvorhaben KI-spezifische Methoden bezüglich der besonderen Anforderungen in der Endlagerforschung zu adaptieren und innerhalb von übergeordneten und spezifischen Handlungsfeldern, d.h. ausgewählten thematische Arbeitsbereichen, zu erarbeiten und zu validieren.
description: Im Rahmen des Projektförderprogrammes des BMWi zur Sicherheitsforschung für kerntechnische Anlagen als Orientierungshilfe für die Erstellung von Projektskizzen und Vorhabenbeschreibungen empfohlenes Papier (siehe auch https://www.ptka.kit.edu/entsorgung-von-hoch-radioaktiven-abfaellen.html)
Fast rates for support vector machines using Gaussian kernels
Creators: name: Steinwart, Ingo
name: Scovel, Clint
Publisher: name: arXiv
Year: 2007
Subjects: subject: Statistics Theory (math.ST)
subject: Machine Learning (stat.ML)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 68Q32 (Primary); 62G20, 62G99, 68T05, 68T10, 41A46, 41A99 (Secondary)

description: For binary classification we establish learning rates up to the order of $n^{-1}$ for support vector machines (SVMs) with hinge loss and Gaussian RBF kernels. These rates are in terms of two assumptions on the considered distributions: Tsybakov's noise assumption to establish a small estimation error, and a new geometric noise condition which is used to bound the approximation error. Unlike previously proposed concepts for bounding the approximation error, the geometric noise assumption does not employ any smoothness assumption.
description: Published at http://dx.doi.org/10.1214/009053606000001226 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)