cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Java Web Start based software for automated quantitative nuclear analysis of prostate cancer and benign prostate hyperplasia
Creators: name: Mohler, James L
name: Singh, Swaroop S
Publisher: name: BioMed Central Ltd
Year: 2005

description: Abstract Background Androgen acts via androgen receptor (AR) and accurate measurement of the levels of AR protein expression is critical for prostate research. The expression of AR in paired specimens of benign prostate and prostate cancer from 20 African and 20 Caucasian Americans was compared to demonstrate an application of this system. Methods A set of 200 immunopositive and 200 immunonegative nuclei were collected from the images using a macro developed in Image Pro Plus. Linear Discriminant and Logistic Regression analyses were performed on the data to generate classification coefficients. Classification coefficients render the automated image analysis software independent of the type of immunostaining or image acquisition system used. The image analysis software performs local segmentation and uses nuclear shape and size to detect prostatic epithelial nuclei. AR expression is described by (a) percentage of immunopositive nuclei; (b) percentage of immunopositive nuclear area; and (c) intensity of AR expression among immunopositive nuclei or areas. Results The percent positive nuclei and percent nuclear area were similar by race in both benign prostate hyperplasia and prostate cancer. In prostate cancer epithelial nuclei, African Americans exhibited 38% higher levels of AR immunostaining than Caucasian Americans (two sided Student's t-tests; P < 0.05). Intensity of AR immunostaining was similar between races in benign prostate. Conclusion The differences measured in the intensity of AR expression in prostate cancer were consistent with previous studies. Classification coefficients are required due to non-standardized immunostaining and image collection methods across medical institutions and research laboratories and helps customize the software for the specimen under study. The availability of a free, automated system creates new opportunities for testing, evaluation and use of this image analysis system by many research groups who study nuclear protein expression.
title: Pictorial Essay on Child Abuse at an Inner-City Hospital
Creators: name: Imsande, Heather
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Trauma
subject: Acute
subject: Socio-economic issues
subject: Normal variants
subject: Ultrasound
subject: Conventional radiography
subject: CT
subject: Trauma
subject: Emergency
subject: Bones

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Discuss the role of radiology in a team approach to suspected child abuse. 2. Learn the radiologic findings in child abuse, as seen at an inner-city hospital. 3. Understand pearls and pitfalls in the radiologic evaluation of suspected child...
Quantitative evaluation of an innovation contest to enhance a sexual health campaign in China
Creators: name: Tang, Songyuan
name: Yang, Bin
name: Zheng, Heping
name: Zhang, Ye
name: Glidden, David
name: Bayus, Barry L
name: Wei, Chongyi
name: Tucker, Joseph
name: Tso, Lai S
name: Tang, Weiming
name: Li, Katherine
Publisher: name: BioMed Central
Year: 2019

description: Abstract
                Background
                Crowdsourcing method is an excellent tool for developing tailored interventions to improve sexual health. We evaluated the implementation of an innovation contest for sexual health promotion in China.
                Methods
                We organized an innovation contest over three months in 2014 for Chinese individuals < 30 years old to submit images for a sexual health promotion campaign. We solicited entries via social media and in-person events. The winning entry was adapted into a poster and distributed to STD clinics across Guangdong Province. In this study, we evaluated factors associated with images that received higher scores, described the themes of the top five finalists, and evaluated the acceptability of the winning entry using an online survey tool.
                Results
                We received 96 image submissions from 76 participants in 10 Chinese provinces. Most participants were youth (< 25 years, 85%) and non-professionals (without expertise in medicine, public health, or media, 88%). Youth were more likely to submit high-scoring entries. Images from professionals in medicine, public health, or media did not have higher scores compared to images from non-professionals. Participants were twice as likely to have learned about the contest through in-person events compared to social media. We adapted and distributed the winning entry to 300 STD clinics in 22 cities over 2 weeks. A total of 8338 people responded to an acceptability survey of the finalist entry. Among them, 79.8% endorsed or strongly endorsed being more willing to undergo STD testing after seeing the poster.
                Conclusions
                Innovation contests may be useful for soliciting images as a part of comprehensive sexual health campaigns in low- and middle-income countries.
Workshop zum Abschluss des B!SON-Projekts
Creators: name: Eppelin, Anita
name: Entrup, Elias
name: Wohlgemuth, Michael
name: Volk, Beatrycze
name: Tullney, Marco
name: Hoppe, Anett
Publisher: name: Zenodo
Year: 2023
Subjects: open access
open access journals
scientific publishing
journal recommender

description: In der Präsentation werden (1) die Projektergebnisse vorgestellt - insbesondere der B!SON Journal Recommender und ein Prototyp für die Einbindung des Dienstes in TYPO3-basierte Websites - und (2) ein Ausblick über die weiteren Planungen der Projektpartner gegeben. Erstellt anlässlich des Workshops zum Abschluss des Projekts "B!SON - Bibliometric and Semantic Open Access Network" am 25.1.2023.
description: This work is funded by the Federal Ministry of Education and Research (BMBF), Germany, funding reference: 16TOA034A.
Finite-size corrections for confined polymers in the extended de Gennes regime
Creators: name: Smithe, T. St Clere
name: Iarko, V.
name: Muralidhar, A.
name: Werner, E.
name: Dorfman, K. D.
name: Mehlig, B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Theoretical results for the extension of a polymer confined to a channel are usually derived in the limit of infinite contour length. But experimental studies and simulations of DNA molecules confined to nanochannels are not necessarily in this asymptotic limit. We calculate the statistics of the span and the end-to-end distance of a semiflexible polymer of finite length in the extended de Gennes regime, exploiting the fact that the problem can be mapped to a one-dimensional weakly self-avoiding random walk. The results thus obtained compare favourably with pruned-enriched Rosenbluth method (PERM) simulations of a three-dimensional discrete wormlike chain model of DNA confined in a nanochannel. We discuss the implications for experimental studies of linear $λ$-DNA confined to nanochannels at the high ionic strengths used in many experiments.
Apolipoprotein E isoform-dependent dendritic recovery of hippocampal neurons following activation of innate immunity
Creators: name: Montine, Kathleen S
Publisher: name: BioMed Central Ltd
Year: 2006

description: Abstract Background Innate immune activation, including a role for cluster of differentiation 14/toll-like receptor 4 co-receptors (CD14/TLR-4) co-receptors, has been implicated in paracrine damage to neurons in several neurodegenerative diseases that also display stratification of risk or clinical outcome with the common alleles of the apolipoprotein E gene (APOE): APOE2, APOE3, and APOE4. Previously, we have shown that specific stimulation of CD14/TLR-4 with lipopolysaccharide (LPS) leads to greatest innate immune response by primary microglial cultures from targeted replacement (TR) APOE4 mice and greatest p38MAPK-dependent paracrine damage to neurons in mixed primary cultures and hippocampal slice cultures derived from TR APOE4 mice. In contrast, TR APOE2 astrocytes had the highest NF-kappaB activity and no neurotoxicity. Here we tested the hypothesis that direct activation of CD14/TLR-4 in vivo would yield different amounts of paracrine damage to hippocampal sector CA1 pyramidal neurons in TR APOE mice. Methods We measured in vivo changes in dendrite length in hippocampal CA1 neurons using Golgi staining and determined hippocampal apoE levels by Western blot. Neurite outgrowth of cultured primary neurons in response to astrocyte conditioned medium was assessed by measuring neuron length and branch number. Results Our results showed that TR APOE4 mice had slightly but significantly shorter dendrites at 6 weeks of age. Following exposure to intracerebroventricular LPS, there was comparable loss of dendrite length at 24 hr among the three TR APOE mice. Recovery of dendrite length over the next 48 hr was greater in TR APOE2 than TR APOE3 mice, while TR APOE4 mice had failure of dendrite regeneration. Cell culture experiments indicated that the enhanced neurotrophic effect of TR APOE2 was LDL related protein-dependent. Conclusion The data indicate that the environment within TR APOE2 mouse hippocampus was most supportive of dendrite regeneration while that within TR APOE4 hippocampus failed to support dendrite regeneration in this model of reversible paracrine damage to neurons from innate immune activation, and suggest an explanation for the stratification of clinical outcome with APOE seen in several degenerative diseases or brain that are associated with activated innate immune response.
title: Congenital pulmonary malformations diagnosed in adulthood, how to recognize them?
Creators: name: De la Via, Esperanza
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Congenital
subject: Contrast agent-intravenous
subject: Digital radiography
subject: CT-High Resolution
subject: CT-Angiography
subject: Pulmonary vessels
subject: Lung
subject: Anatomy

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Congenital pulmonary malformations are usually diagnosed in childhood. However, sometimes the diagnosis is made in adulthood. Radiologists should recognize these types of anomalies to make a proper diagnostic approach. In this paper, congenital...
Emergent Behavior in Strongly Correlated Electron Systems
Creators: name: Pines, David
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: I describe early work on strongly correlated electron systems [SCES] from the perspective of a theoretical physicist who, while a participant in their reductionist top- down beginnings, is now part of the paradigm change to a bottom-up "emergent" approach with its focus on using phenomenology to find the organizing principles responsible for their emergent behavior disclosed by experiment---and only then constructing microscopic models that incorporate these. After considering the organizing principles responsible for the emergence of plasmons, quasiparticles, and conventional superconductivity in SCES, I consider their application to three of SCES's sister systems, the helium liquids, nuclei, and the nuclear matter found in neutron stars. I note some recent applications of the random phase approximation and examine briefly the role that paradigm change is playing in two central problems in our field: understanding the emergence and subsequent behavior of heavy electrons in Kondo lattice materials; and finding the mechanism for the unconventional superconductivity found in heavy electron, organic, cuprate, and iron-based materials.
description: 27 pages, to appear in Rep. Prog. Phys
Citation bias favoring positive clinical trials of thrombolytics for acute ischemic stroke: a cross-sectional analysis
Creators: name: Platts-Mills, Timothy
Publisher: name: BioMed Central
Year: 2016

description: Abstract Background Citation bias occurs when positive trials involving a medical intervention receive more citations than neutral or negative trials of similar quality. Several large clinical trials have studied the use of thrombolytic agents for the treatment of acute ischemic stroke with differing results, thereby presenting an opportunity to assess these trials for evidence of citation bias. We compared citation rates among positive, neutral, and negative trials of alteplase (tPA) and other thrombolytic agents for stroke. Methods We used a 2014 Cochrane Review of thrombolytic therapy for the treatment of acute stroke to identify non-pilot, English-language stroke trials published in MEDLINE-indexed journals comparing thrombolytic therapy with control. We classified trials as positive if there was a statistically significant primary outcome difference favoring the intervention, neutral if there was no difference in primary outcome, or negative for a significant primary outcome difference favoring the control group. Trials were also considered negative if safety concerns supported stopping the trial early. Using Scopus, we collected citation counts through 2015 and compared citation rates according to trial outcomes. Results Eight tPA trials met inclusion criteria: two were positive, four were neutral, and two were negative. The two positive trials received 9080 total citations, the four neutral trials received 4847 citations, and the two negative trials received 1096 citations. The mean annual per-trial citation rates were 333 citations per year for positive trials, 96 citations per year for neutral trials, and 35 citations per year for negative trials. Trials involving other thrombolytic agents were not cited as often, though as with tPA, positive trials were cited more frequently than neutral or negative trials. Conclusions Positive trials of tPA for ischemic stroke are cited approximately three times as often as neutral trials, and nearly 10 times as often as negative trials, indicating the presence of substantial citation bias.
title: Usefulness of imaging techniques in therapeutic decisions in patients with crohn´s disease: a prospective comparison of contrast-enhanced ultrasound and magnetic resonance enterography.
Creators: name: De la Via, Esperanza
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Inflammation
subject: Contrast agent-other
subject: Ultrasound
subject: MR
subject: Gastrointestinal tract
subject: Abdomen

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: CURRENT STATUS OF THE PROBLEM AND JUSTIFICATION OF THE STUDY The different imaging techniques (ultrasound, CT or MRI) help in establishing a solid initial diagnosis of Crohn's disease (CD) with the clinical history, laboratory data and endoscopy...
Kinetic Alfvén turbulence below and above ion-cyclotron frequency
Creators: name: Zhao, J. S.
name: Voitenko, Y. M.
name: Wu, D. J.
name: Yu, M. Y.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: Alfvénic turbulent cascade perpendicular and parallel to the background magnetic field is studied accounting for anisotropic dispersive effects and turbulent intermittency. The perpendicular dispersion and intermittency make the perpendicular-wavenumber magnetic spectra steeper and speed up production of high ion-cyclotron frequencies by the turbulent cascade. On the contrary, the parallel dispersion makes the spectra flatter and decelerate the frequency cascade above the ion-cyclotron frequency. Competition of the above factors results in spectral indices distributed in the interval [-2,-3], where -2 is the index of high-frequency space-filling turbulence, and -3 is the index of low-frequency intermittent turbulence formed by tube-like fluctuations. Spectra of fully intermittent turbulence fill a narrower range of spectral indices [-7/3,-3], which almost coincides with the range of indexes measured in the solar wind. This suggests that the kinetic-scale turbulent spectra are shaped mainly by dispersion and intermittency. A small mismatch with measured indexes of about 0.1 can be associated with damping effects not studied here.
description: 9 Pages, 3 Figures, and 2 Tables
Land use and land cover (LULC) performance modeling using machine learning algorithms: a case study of the city of Melbourne, Australia
Creators: name: Aryal, Jagannath
name: Sitaula, Chiranjibi
name: Frery, Alejandro
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2023

description: AbstractAccurate spatial information on Land use and land cover (LULC) plays a crucial role in city planning. A widely used method of obtaining accurate LULC maps is a classification of the categories, which is one of the challenging problems. Attempts have been made considering spectral (Sp), statistical (St), and index-based (Ind) features in developing LULC maps for city planning. However, no work has been reported to automate LULC performance modeling for their robustness with machine learning (ML) algorithms. In this paper, we design seven schemes and automate the LULC performance modeling with six ML algorithms-Random Forest, Support Vector Machine with Linear kernel, Support Vector Machine with Radial basis function kernel, Artificial Neural Network, Naïve Bayes, and Generalised Linear Model for the city of Melbourne, Australia on Sentinel-2A images. Experimental results show that the Random Forest outperforms remaining ML algorithms in the classification accuracy (0.99) on all schemes. The robustness and statistical analysis of the ML algorithms (for example, Random Forest imparts over 0.99 F1-score for all five categories and p value $$\le$$ ≤ 0.05 from Wilcoxon ranked test over accuracy measures) against varying training splits demonstrate the effectiveness of the proposed schemes. Thus, providing a robust measure of LULC maps in city planning.
Mental health and psychosocial interventions to limit the adverse psychological effects of disasters and emergencies in China: A scoping review
Creators: name: Gen Li
name: Shi, Wei
name: Liang, Di
name: Li, Chunbo
name: Hall, Brian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Scoping Review Protocol: Mental health-related interventions for disasters in China

description: Protocol for a scoping review that aims to systematically map currently available research and other information about mental health and psychosocial responses to natural disasters and other major emergencies in China and to identify any critical gaps in current knowledge about this increasingly important issue.
title: Radiologist On Call: Head and Neck Nontraumatic Emergency Conditions
Creators: name: Pérez Rubiralta, Marta
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Acute
subject: Diagnostic procedure
subject: Contrast agent-intravenous
subject: Computer Applications-3D
subject: MR-Diffusion/Perfusion
subject: MR
subject: CT
subject: Head and neck
subject: Emergency
subject: Ear / Nose / Throat
subject: Inflammation
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: We reviewed the most significant and the more illustrative cases found in the emergency department of our hospital, in order to: – introduce the most frequent entities of the acute non traumatic head and neck pathology – exhibit the radiologic...
ATG8-dependent LMX1B-autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience
Creators: name: Jiménez-Moreno, Natalia
name: Kollareddy, Madhu
name: Stathakos, Petros
name: Moss, Joanna J.
name: Antón, Zuriñe
name: Shoemark, Deborah K.
name: Sessions, Richard B.
name: Witzgall, Ralph
name: Caldwell, Maeve
name: Lane, Jon D.
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Cell death and autophagy, Neuroscience
subject: 570 Biowissenschaften, Biologie

description: The LIM homeodomain transcription factors LMX1A and LMX1B are essential mediators of midbrain dopaminergic neuronal (mDAN) differentiation and survival. Here we show that LMX1A and LMX1B are autophagy transcription factors that provide cellular stress protection. Their suppression dampens the autophagy response, lowers mitochondrial respiration, and elevates mitochondrial ROS, and their inducible overexpression protects against rotenone toxicity in human iPSC-derived mDANs in vitro. Significantly, we show that LMX1A and LMX1B stability is in part regulated by autophagy, and that these transcription factors bind to multiple ATG8 proteins. Binding is dependent on subcellular localization and nutrient status, with LMX1B interacting with LC3B in the nucleus under basal conditions and associating with both cytosolic and nuclear LC3B during nutrient starvation. Crucially, ATG8 binding stimulates LMX1B-mediated transcription for efficient autophagy and cell stress protection, thereby establishing a novel LMX1B-autophagy regulatory axis that contributes to mDAN maintenance and survival in the adult brain
Maternal exercise before and during pregnancy does not impact offspring exercise or body composition in mice
Creators: name: Pomp, Daniel
name: Nehrenberg, Derrick L
name: Hua, Kunjie
Publisher: name: BioMed Central
Year: 2015

description: Abstract Background The genome, the environment, and their interactions simultaneously regulate complex traits such as body composition and voluntary exercise levels. One such environmental influence is the maternal milieu (i.e., in utero environment or maternal care). Variability in the maternal environment may directly impact the mother, and simultaneously has the potential to influence the physiology and/or behavior of offspring in utero, post birth, and into adulthood. Here, we utilized a murine model to examine the effects of the maternal environment in regard to voluntary exercise (absence of wheel running, wheel running prior to gestation, and wheel running prior to and throughout gestation) on offspring weight and body composition (% fat tissue and % lean tissue) throughout development (~3 to ~9 weeks of age). Additionally, we examined the effects of ~6 weeks of maternal exercise (prior to and during gestation) on offspring exercise levels at ~9 weeks of age. Results We observed no substantial effects of maternal exercise on subsequent male or female offspring body composition throughout development, or on the propensity of offspring to engage in voluntary wheel running. At the level of the individual, correlational analyses revealed some statistically significant relationships between maternal and offspring exercise levels, likely reflecting previously known heritability estimates for such traits. Conclusions The current results conflict with previous findings in human and mouse models demonstrating that maternal exercise has the potential to alter offspring phenotypes. We discuss our negative findings in the context of the timing of the maternal exercise and the level of biological organization of the examined phenotypes within the offspring.
Positive solutions of a nonlinear fourth-order integral boundary value problem
Creators: name: Benaicha, Slimane
name: Haddouchi, Faouzi
Publisher: name: arXiv
Year: 2016
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 34B15, 34B18

description: In this paper, the existence of positive solutions for a nonlinear fourth-order two-point boundary value problem with integral condition is investigated. By using Krasnoselskii's fixed point theorem on cones, sufficient conditions for the existence of at least one positive solutions are obtained.
description: 11 pages, V4: Corrections of minor typographic errors
title: CT features of primary lung cancer arising from the pulmonary bullous wall
Creators: name: Fujisawa, Hidefumi
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Liver
subject: Conventional radiography
subject: Diagnostic procedure
subject: Cancer
subject: Pathology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: In this exhibit, we assess the chest CT findings in the many cases of the primary lung cancer arising from the bullous wall correlating with its pathological...
title: Analyzation of radiation resistance of carbon-based materials for accelerator components
Creators: name: Bolz, Philipp
Publisher: name: UNSPECIFIED
Year: 2023

description: Functional materials in high-dose environments have to withstand extreme radiation conditions but factors that limit their radiation hardness are poorly understood. An example are materials for components in particle accelerators such as beam dumps, targets and collimators. With increasing energy and pulse intensities of new accelerator facilities, these beam intercepting devices are exposed to loads with high strain rates. To secure the safe operation of future facilities, the suitability of materials exposed to extreme pulsed beam conditions need to be tested. This work mainly concentrates on graphitic materials including isotropic graphite, carbon fibre reinforced carbon, highly oriented pyrolytic graphite and flexible graphite. The mechanical properties and material changes with increasing ion fluence are investigated using nano- and microindentation and nanoimpact measurements. Samples are irradiated at the universal linear accelerator UNILAC of the GSI Helmholtz Centre for Heavy Ion Research. The experiments are performed with various types of ions of MeV to GeV energies achieving fluences up to 2e14 ions/cm². In isotropic graphite and carbon fibre reinforced carbon, large changes in Young’s modulus of up to 300 % and in hardness by more than 1000 % compared to the pristine values are observed. These pronounced material modifications occur if the energy loss of the ions surpasses approximately 18 keV/nm. By nanoimpact measurements hardening is revealed, leading to embrittlement at fluences above 3e13 ions/cm². Raman spectroscopy indicates that these severe changes of mechanical properties are related to beam-induced allotropic transformation of the graphite structure into a disordered structure similar to glassy carbon. To obtain further information about the dynamic response of the materials to ion impacts, in-situ measurements during the irradiation are required. Disc-shaped samples are exposed to short pulses of uranium ions corresponding to a deposited power density of ~3 MW/cm³. The resulting thermal stress produces pressure waves in the samples. The velocity of the respective motion of the target surface is monitored by laser Doppler vibrometry. The velocity signal recorded as a function of time reveals bending modes as the dominant components. With accumulated radiation damage, the bending mode frequency shifts toward higher values. Based on this shift, the Young’s modulus of irradiated isotropic graphite and carbon fibre reinforced carbon are determined by comparison with FEM simulations. Young’s modulus values deduced from microindentation measurements are similar confirming the validity of the method. Beam-induced stress waves remain in the elastic regime and no large-scale damage effects are observed in graphite. Tungsten and copper show no beam-induced changes while glassy carbon and hexagonal boron nitride have lower radiation resistance evident by chipping and cracks risking material failure when applied in high dose environment.
Marker assisted introgression of semi-dwarfing (sd1) gene in Katarni rice (Oryza sativa L.) landrace
Creators: name: Kumar, Mankesh
name: Vaibhav, Kumar
name: Chandra, Anamika
name: Suvidha, Kumari
name: Mahto, Divya
name: ., Satyendra
name: Singh, Prabhash Kumar
name: Sinha, Sweta
Publisher: name: Brill Online
Year: 2022
Subjects: Ecology not elsewhere classified

description: ‘Katarni Rice’ is a fine quality scented rice landrace of Bihar, India and has tremendous export potential and commercial value. This is a preferred rice in the state due to its flavour, palatability and popcorn like essence before and after cooking. But its area has been shrunken drastically in recent years due to its low yielding (25-30 Q/ha) ability caused due tall and week stature and lodging tendency at maturity. To overcome this problem, marker assisted introgression of semi-dwarfing (sd1) gene from semi-dwarf and high yielding rice varieties Rajendra Sweta and BPT5204 was attempted. Parental polymorphism was obtained through 109 SSR markers. The gene specific markers for fragrance and semi-dwarfing genes were used in the segregants to track their transfer. Recombinant selection was done for the donor genome segments flanking to the target gene i.e., sd1 followed by background selection through genome wide polymorphic SSR markers. More than 90% recurrent parent genome recovery was observed and the selected plants showed a reduction of plant height and flowering time in comparison to Katarni in the successive backcross generation along with the retention of aroma. The identified lines can be evaluated further in multilocation trials to release it as a sustainable high yielding aromatic genotype.
Atelier 3 : Ouvre ta recherche
Creators: name: AZILAN, Innocent
Publisher: name: Zenodo
Year: 2023
Subjects: Open Science
Afrique
Ouvre Ta Recherche

description: Cet atelier (le dernier) s'inscrit dans une série de 3 ateliers "Ouvre Ta Recherche", animé par le doctorant Innocent AZILAN, à l'endroit des doctorants, masterants et nouveaux chercheurs de l'Université de Lomé. Ces ateliers portent sur plusieurs thématiques, dont la documentation, la publicisation de la recherche, l'ouverture de la recherche et l'invisibilité des productions scientifiques à l'Université de Lomé.
Erratum to: Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis
Creators: name: Philpot, Benjamin
name: Sidorov, Michael S
Publisher: name: BioMed Central
Year: 2017

description: After publication of our article [1], we became aware that
there were two minor data loading and analysis scripting
errors in the human EEG data processing pipeline. These
errors affected the channel loading/grouping and sleep/
wake coding of EEG data. We have re-analysed all the
data affected by these errors. The errors do not affect any
interpretations or conclusions, thus no changes to the text
are required apart from correcting p values and raw values
affected by the errors. There are no changes to statistical
significance or lack-thereof. The errors affect data presented
in Fig. 3, Fig. 4, Fig. 5, and Additional file 3: Figure
S3 and thus we have re-plotted these figures (see below).
title: Do you have eyes for the Eagle? - radiological aspects of the Eagle syndrome
Creators: name: Calin, Adriana
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Hyperplasia / Hypertrophy
subject: Calcifications / Calculi
subject: Normal variants
subject: Education
subject: Diagnostic procedure
subject: CT
subject: Conventional radiography
subject: Head and neck
subject: Anatomy

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: • to define and to detail the two types of Eagle syndrome • to depict the radiological aspects leading to Eagle syndrome • to underline the importance of sectional imaging in the management of the...
Supplementary document for Inverse-designed Integrated All-optical Nonlinear Activators for Optical Computing - 7140325.pdf
Creators: name: Wang, Jun
name: YANG, ZHAN
name: Yan, Zhouyuan
name: He, Jiajing
name: Hu, Yibiao
name: LI, XIAOBO
name: Dong, Ningning
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Supporting Information
title: Evaluation of renal trauma in the emergency context: the role of computed tomography
Creators: name: Mota, Alexandre
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Trauma
subject: Kidney
subject: CT
subject: Diagnostic procedure
subject: Trauma
subject: Acute

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review the role of computed tomography (CT) on the evaluation of renal trauma. To illustrate, describe and illustrate the findings in renal trauma according to the American Association for the Surgery of Trauma (AAST) classification. To review...
The Global Network Maternal Newborn Health Registry: a multi-national, community-based registry of pregnancy outcomes
Creators: name: Bauserman, Melissa
name: Bose, Carl
Publisher: name: BioMed Central
Year: 2015

description: Abstract Background The Global Network for Women's and Children's Health Research (Global Network) supports and conducts clinical trials in resource-limited countries by pairing foreign and U.S. investigators, with the goal of evaluating low-cost, sustainable interventions to improve the health of women and children. Accurate reporting of births, stillbirths, neonatal deaths, maternal mortality, and measures of obstetric and neonatal care is critical to efforts to discover strategies for improving pregnancy outcomes in resource-limited settings. Because most of the sites in the Global Network have weak registration within their health care systems, the Global Network developed the Maternal Newborn Health Registry (MNHR), a prospective, population-based registry of pregnancies at the Global Network sites to provide precise data on health outcomes and measures of care. Methods Pregnant women are enrolled in the MNHR if they reside in or receive healthcare in designated groups of communities within sites in the Global Network. For each woman, demographic, health characteristics and major outcomes of pregnancy are recorded. Data are recorded at enrollment, the time of delivery and at 42 days postpartum. Results From 2010 through 2013 Global Network sites were located in Argentina, Guatemala, Belgaum and Nagpur, India, Pakistan, Kenya, and Zambia. During this period, 283,496 pregnant women were enrolled in the MNHR; this number represented 98.8% of all eligible women. Delivery data were collected for 98.8% of women and 42-day follow-up data for 98.4% of those enrolled. In this supplement, there are a series of manuscripts that use data gathered through the MNHR to report outcomes of these pregnancies. Conclusions Developing public policy and improving public health in countries with poor perinatal outcomes is, in part, dependent upon understanding the outcome of every pregnancy. Because the worst pregnancy outcomes typically occur in countries with limited health registration systems and vital records, alternative registration systems may prove to be highly valuable in providing data. The MNHR, an international, multicenter, population-based registry, assesses pregnancy outcomes over time in support of efforts to develop improved perinatal healthcare in resource-limited areas. Study Registration: The Maternal Newborn Health Registry is registered at Clinicaltrials.gov (ID# NCT01073475).
A compact and reconfigurable silicon nitride time-bin entanglement circuit
Creators: name: Xiong, C.
name: Zhang, X.
name: Mahendra, A.
name: He, J.
name: Choi, D. -Y.
name: Chae, C. J.
name: Marpaung, D.
name: Leinse, A.
name: Heideman, R. G.
name: Hoekman, M.
name: Roeloffzen, C. G. H.
name: Oldenbeuving, R. M.
name: van Dijk, P. W. L.
name: Taddei, C.
name: Leong, P. H. W.
name: Eggleton, B. J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Photonic chip based time-bin entanglement has attracted significant attention because of its potential for quantum communication and computation. Useful time-bin entanglement systems must be able to generate, manipulate and analyze entangled photons on a photonic chip for stable, scalable and reconfigurable operation. Here we report the first time-bin entanglement photonic chip that integrates time-bin generation, wavelength demultiplexing and entanglement analysis. A two-photon interference fringe with an 88.4% visibility is measured (without subtracting any noise), indicating the high performance of the chip. Our approach, based on a silicon nitride photonic circuit, which combines the low-loss characteristic of silica and tight integration features of silicon, paves the way for scalable real-world quantum information processors.
description: 4 pages, 5 figures
MPEC 2024-R90 : 2002 CP4
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: CT arthrography of the shoulder: how "to do it"
Creators: name: Shah, Amit
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Education and training
subject: Arthrography
subject: CT
subject: Musculoskeletal joint

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Toreview the technique in performing a CT arthrogram of the shoulder. In this poster we discuss: Normal anatomy of the gleno-humeral joint Indications of CT arthrogram Interventional techniques using the anterior and posterior approach Pictorial...
Endemic Kaposi sarcoma in HIV-negative children and adolescents: an evaluation of overlapping and distinct clinical features in comparison with HIV-related disease
Creators: name: Dittmer, Dirk P
name: Kamiyango, William
name: Ozuah, Nmazuo W
name: Peckham-Gregory, Erin C
name: Allen, Carl E
name: Mehta, Parth S
name: Legarreta, Alejandra
name: Martin, Stephen C
name: El-Mallawany, Nader K
name: Scheurer, Michael E
name: Kazembe, Peter N
name: McAtee, Casey L
name: Villiera, Jimmy
name: Kovarik, Carrie L
name: Chiao, Elizabeth Y
Publisher: name: BioMed Central
Year: 2018

description: Abstract
                Background
                Endemic Kaposi sarcoma (KS) was first described in African children over fifty years ago, but has recently been overshadowed by HIV-related disease. We aimed to evaluate the similarities and differences between endemic HIV-negative and epidemic HIV-positive pediatric KS in a KS-associated herpesvirus-endemic region of Africa.
                Methods
                We describe clinical characteristics of 20 HIV-negative children with endemic KS over a six-year period and compare findings with a historical control—an HIV-related pediatric KS cohort from Lilongwe, Malawi.
                Results
                The HIV-negative endemic KS cohort was 70% male with a median age of 9.3 years. Lymph node involvement was present in 50%, hyperpigmented skin lesions in 45%, and woody edema in 40%. One patient (5%) presented with oral KS involvement and no patients presented initially with visceral KS. Significant anemia (hemoglobin < 8 g/dL) and thrombocytopenia (platelet count < 100 × 109/L) were found at time of original KS diagnosis in 45 and 40% respectively. In both HIV-negative and HIV-positive cohorts, lymphadenopathy was the most common presentation, prototypical skin lesions were often absent, severe cytopenias were a common clinical feature, and treatment outcomes were similar. Patients with endemic KS demonstrated less frequent oral involvement (5% versus 29%, P = 0.03) and a lower proportion of patients with visceral involvement (0% versus 16%, P = 0.06).
                Conclusions
                These data suggest clinical overlap between epidemiological variants. Treatment protocols for pediatric KS in sub-Saharan Africa should be devised to include both endemic HIV-negative and epidemic HIV-related disease to better define the clinical and biological comparison.
GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice
Creators: name: Dee, Rachel
name: O’Neill, Thomas J
name: Cheng, Zhaokang
name: Taylor, Joan
name: Lenhart, Kaitlin C
name: Mack, Christopher P.
Publisher: name: BioMed Central
Year: 2015

description: Abstract Background The plasma membranes of striated muscle cells are particularly susceptible to rupture as they endure significant mechanical stress and strain during muscle contraction, and studies have shown that defects in membrane repair can contribute to the progression of muscular dystrophy. The synaptotagmin-related protein, dysferlin, has been implicated in mediating rapid membrane repair through its ability to direct intracellular vesicles to sites of membrane injury. However, further work is required to identify the precise molecular mechanisms that govern dysferlin targeting and membrane repair. We previously showed that the bin–amphiphysin–Rvs (BAR)–pleckstrin homology (PH) domain containing Rho-GAP GTPase regulator associated with focal adhesion kinase-1 (GRAF1) was dynamically recruited to the tips of fusing myoblasts wherein it promoted membrane merging by facilitating ferlin-dependent capturing of intracellular vesicles. Because acute membrane repair responses involve similar vesicle trafficking complexes/events and because our prior studies in GRAF1-deficient tadpoles revealed a putative role for GRAF1 in maintaining muscle membrane integrity, we postulated that GRAF1 might also play an important role in facilitating dysferlin-dependent plasma membrane repair. Methods We used an in vitro laser-injury model to test whether GRAF1 was necessary for efficient muscle membrane repair. We also generated dystrophin/GRAF1 doubledeficient mice by breeding mdx mice with GRAF1 hypomorphic mice. Evans blue dye uptake and extensive morphometric analyses were used to assess sarcolemmal integrity and related pathologies in cardiac and skeletal muscles isolated from these mice. Results Herein, we show that GRAF1 is dynamically recruited to damaged skeletal and cardiac muscle plasma membranes and that GRAF1-depleted muscle cells have reduced membrane healing abilities. Moreover, we show that dystrophin depletion exacerbated muscle damage in GRAF1-deficient mice and that mice with dystrophin/GRAF1 double deficiency phenocopied the severe muscle pathologies observed in dystrophin/dysferlin-double null mice. Consistent with a model that GRAF1 facilitates dysferlin-dependent membrane patching, we found that GRAF1 associates with and regulates plasma membrane deposition of dysferlin. Conclusions Overall, our work indicates that GRAF1 facilitates dysferlin-dependent membrane repair following acute muscle injury. These findings indicate that GRAF1 might play a role in the phenotypic variation and pathological progression of cardiac and skeletal muscle degeneration in muscular dystrophy patients.
Gas-phase oxygen abundances and radial metallicity gradients in the two nearby spiral galaxies NGC7793 and NGC4945
Creators: name: Stanghellini, Letizia
name: Magrini, Laura
name: Casasola, Viviana
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Gas-phase abundances in HII regions of two spiral galaxies, NGC7793 and NGC4945, have been studied to determine their radial metallicity gradients. We used the strong-line method to derive oxygen abundances from spectra acquired with GMOS-S, the multi-object spectrograph on the 8m- Gemini South telescope. We found that NGC7793 has a well-defined gas-phase radial oxygen gradient of -0.321 $\pm$ 0.112 dex R$_{\rm 25}^{-1}$ (or -0.054 $\pm$ 0.019 dex kpc$^{-1}$) in the galactocentric range 0.17$
description: ApJ, in press
title: Arteriovenous Fistulas and Hypoperfusion Ischemic Syndrome in Patients on Haemodialysis.
Creators: name: Pascagaza, Alejandro
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Ischaemia / Infarction
subject: Haemodynamics / Flow dynamics
subject: Fistula
subject: Venous access
subject: Diagnostic procedure
subject: Ultrasound-Spectral Doppler
subject: Fluoroscopy
subject: CT-Angiography
subject: Vascular
subject: Interventional vascular
subject: Extremities

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To understand the clinical importance of the Distal Hypoperfusion Ischemic Syndrome (DHIS) in haemodialysis patients and the importance of a correct diagnosis using Duplex Doppler Ultrasound (DDU), Digitial Substraction Angiography (DSA) and...
Phacus limnophila var. swirenkoi J. Juran 2017, comb. nov.
Creators: name: Juráň, Josef
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Protozoa
Euglenozoa
Euglenophyceae
Euglenida
Phacidae
Phacus
Phacus limnophila
Phacus limnophila var. swirenkoi (w.m. arnoldi) j. juráň

description: Phacus limnophila var. swirenkoi (W.M. Arnoldi) J. Juráň comb. nov.
 Basionym: Euglena swirenkoi W.M. Arnoldi [Zhurn. Russk. Bot. Obshch. 7: 56, fig. 1. 1924]
 Synonyms: Euglena limnophila var. minor R. Dreżepolski [Kosmos (Lwów) 50: 245, 268, fig. 162. 1925] non Euglena limnophila var. minor H. Kufferath [Bull. Soc. Roy. Bot. Belgique 74: 100, fig. 4. 1942]
After Wołowski (2011), this variety is in its dimensions smaller than the typical variety (width 7,5–12 μm, length 24–40–48 μm) as well as in the length to width ratio (width 7,5–12–13,6 μm, length 40–90 μm).
 Additionally, morphological description of Phacus ulula suggests its affiliation to the Monomorphina genus renewed by Marin et al. (2003). New combination was made:
description: Published as part of Juráň, Josef, 2017, The checklist of photosynthetic euglenoids (order Euglenales) of the Czech Republic: ecology, taxonomy, distribution, pp. 1-16 in Phytotaxa 317 (1) on page 5, DOI: 10.11646/phytotaxa.317.1.1, http://zenodo.org/record/13696201
X-ray spectral evolution of V404 Cygni in the initial phase of the 2015 outburst
Creators: name: Natalucci, Lorenzo
name: Fiocchi, Mariateresa
name: Bazzano, Angela
name: Ubertini, Pietro
name: Roques, Jean-Pierre
name: Jourdain, Elisabeth
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The black hole binary GS 2023+338 exhibited an unprecedently bright outburst on June 2015. Since June 17th, the high energy instruments on board INTEGRAL detected an extremely variable emission during both bright and low luminosity phases, with dramatic variations of the hardness ratio on time scales of ~seconds. The analysis of the IBIS and SPI data reveals the presence of hard spectra in the brightest phases, compatible with thermal Comptonization with temperature kTe ~ 40 keV. The seed photons temperature is best fit by kT0 ~ 7 keV, that is too high to be compatible with blackbody emission from the disk. This result is consistent with the seed photons being provided by a different source, that we hypothesize to be a synchrotron driven component in the jet. During the brightest phase of flares, the hardness shows a complex pattern of correlation with flux, with a maximum energy released in the range 40-100 keV. The hard X-ray variability for E > 50 keV is correlated with flux variations in the softer band, showing that the overall source variability cannot originate entirely from absorption, but at least part of it is due to the central accreting source.
description: 5 pages, 4 figures, accepted for publication in Astrophysical Journal Letters