cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Variance Based Scheduling Algorithm with Relay Selection and Resource Allocation in Cooperative OFDMA Networks
Creators: name: Basly, Maryam
name: Kochkar, Hedia
name: Bouallegue, Ammar
Publisher: name: arXiv
Year: 2013
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Nowadays the radio interface of several standards is enhanced with advanced technologies such as OFDMA and extension technology such as relay. By using those promising transmission technology for the next generation wireless communications, scheduling problem becomes more crucial and challenging. In our work, we aim to maximize the overall system capacity while selecting the most suitable relay station under fairness constraint among both users and relay station by proposing a Gap- based scheduling. This one considers the channel state information and the unbalanced rate capacity of the two hops links. Simulations results show the effectiveness of our approach in terms of fairness and the overall system performance.
description: 6 pages 4 figures
Pharmacophore modelling-based drug repurposing approaches for monkeypox therapeutics
Creators: name: Alagarsamy, V.
name: Sundar, P. Shyam
name: Solomon, V. Raja
name: Narendhar, B.
name: Sulthana, M. T.
name: Rohitha, Kotha
name: Dhanwar, Sangeeta
name: Aishwarya, A. Dharshini
name: Murugesan, S.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Monkeypox is a zoonotic viral disease that mainly affects tropical rainforest regions of central and west Africa, with sporadic exportations to other places. Since there is no cure, treating monkeypox with an antiviral drug developed for smallpox is currently acceptable. Our study mainly focused on finding new therapeutics to target monkeypox from existing compounds or medications. It is a successful method for discovering or developing medicinal compounds with novel pharmacological or therapeutic applications. In this study, homology modelling developed the Monkeypox VarTMPK (IMNR) structure. Ligand-based pharmacophore was generated using the best docking pose of standard ticovirimat. Further, molecular docking analysis showed compounds, tetrahydroxycurcumin, procyanidin, rutin, vicenin-2, kaempferol 3-(6''-malonylglucoside) were the top five binding energy compounds against VarTMPK (1MNR). Furthermore, we carried out MD simulations for 100 ns for the six compounds, including reference based on the binding energies and interactions. MD studies revealed that as ticovirimat interacted with residues Lys17, Ser18, and Arg45, all the above five compounds interacted with the same amino acids at the active site during docking and simulation studies. Among all the compounds, ZINC4649679 (Tetrahydroxycurcumin) was shown to have the highest binding energy −9.7 kcal/mol and also observed stable protein-ligand complex during MD studies. ADMET profile estimation showed that the docked phytochemicals were safe. However, further biological assessment through a wet lab is essential to measure the efficacy and safety of the compounds. Communicated by Ramaswamy H. Sarma
On degenerations of plane Cremona transformations
Creators: name: Blanc, Jérémy
name: Calabri, Alberto
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14E07

description: This article studies the possible degenerations of plane Cremona transformations of some degree into maps of smaller degree.
description: 21 pages, corrected typos and Proposition 3.21, Mathematische Zeitschrift, published online on 2015/9/25
Elasticity of DNA and the effect of Dendrimer Binding
Creators: name: Mogurampelly, Santosh
name: Nandy, Bidisha
name: Netz, Roland R.
name: Maiti, Prabal K.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biomolecules (q-bio.BM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Negatively charged DNA can be compacted by positively charged dendrimers and the degree of compaction is a delicate balance between the strength of the electrostatic interaction and the elasticity of DNA. We report various elastic properties of short double stranded DNA (dsDNA) and the effect of dendrimer binding using fully atomistic molecular dynamics and numerical simulations. In equilibrium at room temperature, the contour length distribution P(L) and end-to-end distance distribution P(R) are nearly Gaussian, the former gives an estimate of the stretch modulus γ_1 of dsDNA in quantitative agreement with the literature value. The bend angle distribution P(θ) of the dsDNA also has a Gaussian form and allows to extract a persistence length, L_p of 43 nm. When the dsDNA is compacted by positively charged dendrimer, the stretch modulus stays invariant but the effective bending rigidity estimated from the end-to-end distance distribution decreases dramatically due to backbone charge neutralization of dsDNA by dendrimer. We support our observations with numerical solutions of the worm-like-chain (WLC) model as well as using non-equilibrium dsDNA stretching simulations. These results are helpful in understanding the dsDNA elasticity at short length scales as well as how the elasticity is modulated when dsDNA binds to a charged object such as a dendrimer or protein.
description: 21 pages, 5 figures
Synergy of Topoisomerase and Structural-Maintenance-of-Chromosomes Proteins Creates a Universal Pathway to Simplify Genome Topology
Creators: name: Orlandini, Enzo
name: Marenduzzo, Davide
name: Michieletto, Davide
Publisher: name: arXiv
Year: 2018
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: Biomolecules (q-bio.BM)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Topological entanglements severely interfere with important biological processes. For this reason, genomes must be kept unknotted and unlinked during most of a cell cycle. Type II Topoisomerase (TopoII) enzymes play an important role in this process but the precise mechanisms yielding systematic disentanglement of DNA in vivo are not clear. Here we report computational evidence that Structural Maintenance of Chromosomes (SMC) proteins -- such as cohesins and condensins -- can cooperate with TopoII to establish a synergistic mechanism to resolve topological entanglements. SMC-driven loop extrusion (or diffusion) induces the spatial localisation of essential crossings in turn catalysing the simplification of knots and links by TopoII enzymes even in crowded and confined conditions. The mechanism we uncover is universal in that it does not qualitatively depend on the specific substrate, whether DNA or chromatin, or on SMC processivity; we thus argue that this synergy may be at work across organisms and throughout the cell cycle.
description: main text + SI; accepted in PNAS; supplementary movies can be found at https://www2.ph.ed.ac.uk/~dmichiel/Gallery.html
title: Maria Virgo Sine Macula Concepta Ferdinando III, Romanorum Imperatorii In Specvlo Repraesentata Octavo die Decembris; 1651
title: Quo Antiquissima & Celeberrima Universitas Viennensis Festvm Immaculate Conceptae Virginis Solenni ritu in Basilicâ D. Stephani celebrabat
titleType: Subtitle
Creators: name: Khuffstain, Gotthulph
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2012

description: Vorlageform des Erscheinungsvermerks: Viennae Austriae, Typis Matthaei Comerovij, S.C.M. Typ. Anno Salutis 1651
Intensive electron antineutrino source with well defined hard spectrum on the base of nuclear reactor and 8-lithium transfer. The promising experiment for sterile neutrinos search
Creators: name: Lyashuk, V. I.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The new concept of antineutrino source for future short-baseline experiments is discussed. The source ensures: 1) well defined hard antineutrino flux; 2) the rate of counts more than ~(1E+2 - 1E+3) per day in the detector volume about cubic meter; 3) low level of count errors - < 1%. The proposed source is based on (n,gamma)-activation of 7Li near the reactor active zone and transport of the fast beta-decaying 8Li isotope toward a remote neutrino detector and back in the closed loop. The proposed experiment allows to detect (electron antineutrino, p)-interaction with high precision and directed to search of sterile neutrinos with squared-mass difference between sterile and active neutrinos ~1 eV2. The results of simulation for (3+1) and (3+2) sterile neutrino models indicate the space regions for search of electron antineutrino-disappearance outside the spectrum errors.
description: 14 pages; 9 figures; 34 references
Condylura Illiger 1811
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Condylura

description: Condylura Illiger, 1811. Prodr. Syst. Mamm. et Avium., p. 125. ISIS NUMBER: 5301403006001000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
The Bulk-to-Boundary Propagator in Black Hole Microstate Backgrounds
Creators: name: Chen, Hongbin
name: Fitzpatrick, A. Liam
name: Kaplan, Jared
name: Li, Daliang
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: First-quantized propagation in quantum gravitational AdS$_3$ backgrounds can be exactly reconstructed using CFT$_2$ data and Virasoro symmetry. We develop methods to compute the bulk-to-boundary propagator in a black hole microstate, $\langle ϕ_L \mathcal{O}_L \mathcal{O}_H \mathcal{O}_H\rangle$, at finite central charge. As a first application, we show that the semiclassical theory on the Euclidean BTZ solution sharply disagrees with the exact description, as expected based on the resolution of forbidden thermal singularities, though this effect may appear exponentially small for physical observers.
description: 34+27 pages, 7 figures; v2: typos corrected
title: „Hoffnungslos durchseucht“. Zur diskursiven Infektiosität des Humanen Papilloma Virus in den deutschen Medien, 2006–2009
Creators: name: Sabisch, Katja
Publisher: name: Humboldt-Universität zu Berlin
Year: 2009
Subjects: subject: Diskurs
subject: Gesundheit
subject: HPV
subject: Körper
subject: Krebs
subject: Medikalisierung
subject: Medizin
subject: Pathogenisierung
subject: ddc:303

description: Die Kritische Diskursanalyse der aktuellen Debatte über die Impfung gegen Humane Papilloma Viren (HPV) zeigt, dass die als „Impfung gegen Krebs“ betitelte Kampagne von einer Medikalisierung und Pathogenisierung des weiblichen Körpers flankiert wird. Aus medizin- und geschlechtersoziologischer Perspektive ist festzustellen, dass die Neu-Konfiguration der Krankheit Krebs als Infektionskrankheit mit einer Neu-Konfiguration des Mädchenkörpers als behandlungsbedürftig und ansteckend einhergeht.
Condylura cristata
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Condylura
Condylura cristata

description: Condylura cristata (Linnaeus, 1758). Syst. Nat., 10th ed., 1:53. TYPE LOCALITY: U.S.A., Pennsylvania. DISTRIBUTION: Georgia and N. W. South Carolina (U.S.A.) to Nova Scotia and Labrador (Canada); Great Lakes region to S. E. Manitoba. COMMENT: Reviewed by Peterson and Yates, 1980, Mamm. Species, 129:1-4. ISIS NUMBER: 5301403006001001001.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
description: {"references": ["Peterson, K. E., and T. I. Yates. 1980. Condylura cristata. Mammalian Species, 129: 1 - 4."]}
Socio-demographic, health, treatment, and labour market characteristics of sick-listed employees diagnosed with and treated for a mental disorder in Germany
Creators: name: Starke, Fiona
name: Houkes, Inge
name: Sikora, Alexandra
name: Wegewitz, Uta
name: de Rijk, Angelique
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Science Policy
Mental Health

description: To examine the socio-demographic, health, treatment, organisation, job, and labour market characteristics of 484 German sick-listed employees diagnosed with a mental disorder (MD), along with gender differences. This cross-sectional study used online baseline self-report data from sick-listed employees diagnosed with and treated for a MD, recruited as part of an evaluation trial for a return to work (RTW) intervention (DRKS00026232). Descriptives and t-tests/chi-squared tests were performed. Mean age was 42.6 years (range 20–60 years). Nearly 60% were female, 31% highly educated, and more than half fell into lower gross household income groups. Recurrent depression was a common diagnosis. The employees reported moderate depressive symptoms, low RTW self-efficacy, and poor work ability. Gradual RTW was rated the most common workplace accommodation need for RTW. Significant gender differences were found regarding socio-demographic, health, job, and labour market characteristics. Despite the majority having permanent, fulltime, white-collar jobs, the results highlight the vulnerability of persons with a diagnosed MD in the labour market, suggesting an urgent need for more clinical and work-directed aftercare. Women seem more disadvantaged than men but not regarding treatment and organisation characteristics, emphasising the importance of addressing gender differences in mental health and practice. Sick-listed employees diagnosed with and treated for a MD report moderate depressive symptoms, low RTW self-efficacy, poor work ability, and lower income, which implies a need for more clinical and work-directed aftercare.Employees with a MD are more likely to exit the labour market prematurely.Comprehensive knowledge of the characteristics of sick-listed employees diagnosed with and treated for a MD is crucial for targeting interventions to promote RTW.The treatment and preparation for RTW should be tailored more towards the specific problems female employees with a diagnosed MD experience. Sick-listed employees diagnosed with and treated for a MD report moderate depressive symptoms, low RTW self-efficacy, poor work ability, and lower income, which implies a need for more clinical and work-directed aftercare. Employees with a MD are more likely to exit the labour market prematurely. Comprehensive knowledge of the characteristics of sick-listed employees diagnosed with and treated for a MD is crucial for targeting interventions to promote RTW. The treatment and preparation for RTW should be tailored more towards the specific problems female employees with a diagnosed MD experience.
Investigating magnetic activity of F stars with the it Kepler mission
Creators: name: Mathur, S.
name: Garcia, R. A.
name: Ballot, J.
name: Ceillier, T.
name: Salabert, D.
name: Metcalfe, T. S.
name: Regulo, C.
name: Jimenez, A.
name: Bloemen, S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The dynamo process is believed to drive the magnetic activity of stars like the Sun that have an outer convection zone. Large spectroscopic surveys showed that there is a relation between the rotation periods and the cycle periods: the longer the rotation period is, the longer the magnetic activity cycle period will be. We present the analysis of F stars observed by Kepler for which individual p modes have been measure and with surface rotation periods shorter than 12 days. We defined magnetic indicators and proxies based on photometric observations to help characterise the activity levels of the stars. With the Kepler data, we investigate the existence of stars with cycles (regular or not), stars with a modulation that could be related to magnetic activity, and stars that seem to show a flat behaviour.
description: 2 pages, 1 figure, proceedings of IAU Symposium 302 'Magnetic fields through stellar evolution', 25-30 August 2013, Biarritz, France
Pharmacophore based virtual screening & molecular docking approach for identification of mycobacterial membrane protein large 3 (MmpL3) inhibitors
Creators: name: Dhulap, Abhijeet
name: Banerjee, Paromita
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Tuberculosis (TB) disease continues to remain one of the global threats for mankind. Till date many antibacterial compounds have been identified to target mycobacterium tuberculosis (MTB). However, the mutating nature of the mycobacteria has always posed a challenge for designing newer drugs which can target both the non-mutating and mutating forms of TB. In this process, Mycobacterial membrane protein Large 3 (MmpL3) transporter was identified as one of the key targets for inhibiting tuberculosis. Herein we have made an effort to find potential inhibitors against MmpL3 by using a pharmacophore-based virtual screening workflow, followed by molecular docking studies and molecular dynamic simulations. Based on a set of 220 compounds showing anti-tubercular activity proposed to target MmpL3 transporter with MIC values ranging from 0.003 to 737 μM, a 5-point pharmacophore ADHHR_2 model possessing one hydrogen acceptor, one hydrogen donor, two hydrophobic groups and an aromatic ring system was generated. The model validated by enrichment study was used to screen Asinex and DrugBank database to identify a potential lead compound such as DrugBank_6059 that was found to show better binding affinity (−11.36) and hydrophobic interactions with target protein in comparison to standard drug SQ109. Communicated by Ramaswamy H. Sarma
Control over band structure and tunneling in Bilayer Graphene induced by velocity engineering
Creators: name: Cheraghchi, Hosein
name: Adinehvand, Fatemeh
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The band structure and transport properties of massive Dirac Fermions in bilayer graphene with velocity modulation in space are investigated in presence of the previously created band gap. It is pointed out that the velocity engineering is considered as a factor to control the band gap of symmetry-broken bilayer graphene. The band gap is direct and independent of velocity value if velocity modulated in two layers is set up equally. Otherwise, in the case of interlayer asymmetric velocity, not only the band gap is indirect, but also the electron-hole symmetry fails. This band gap is controllable by the ratio of the velocity modulated in the upper layer to the velocity modulated in the lower layer. In more detail, the shift of momentum from the conduction band edge to the valence band edge can be engineered by the gate bias and velocity ratio. A transfer matrix method is also elaborated to calculate four-band coherent conductance through a velocity barrier possibly subjected to a gate bias. Electronic transport depends on the ratio of velocity modulated inside the barrier to the one for surrounding regions. As a result, a quantum version of total internal reflection is observed for enough thick velocity barriers. Moreover, a transport gap originating from the applied gate bias is engineered by modulating velocity of the carriers in the upper and lower layers.
description: 11 pages, 9 figures
Guidelines for Developing Internal Supervision in Basic Educational School in Nong Bua Daeng District, Chaiyaphum Province under Chaiyaphum Primary Educational Service Area 1
Creators: name: Parinya Amphawa
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Internal Supervision
Guidelines for Developing Internal Supervision

description: Interdisciplinary Academic and Research Journal, 3, 4, 853-874
Desmana Guldenstaedt 1777
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Desmana

description: Desmana Guldenstaedt, 1777. Besehaft. Berlin Ges. Naturforsch Fr., 3:108. ISIS NUMBER: 5301403006002000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
Erotemata Miscellanea ex utroq[ue] iure deprompta; 1608
Creators: name: Martini, Friedrich
name: Dornsperger, Johann Caspar
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2012

description: Vorlageform des Erscheinungsvermerks: Fribvrgi Brisgoiae. Excudebat Martinvs Bocklervs. Anno M. DC. VIII.
Effects of Microstructure Formation on the Stability of Vapor Deposited Glasses
Creators: name: Moore, Alex R.
name: Walsh, Patrick J.
name: Fakhraai, Zahra
name: Riggleman, Robert A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Glasses formed by physical vapor deposition (PVD) are an interesting new class of materials, exhibiting properties thought to be equivalent to those of glasses aged for thousands of years. Exerting control over the structure and properties of PVD glasses formed with different types of glass-forming molecules is now an emerging challenge. In this work, we study coarse grained models of organic glass formers containing fluorocarbon tails of increasing length, corresponding to an increased tendency to form microstructures. We use simulated PVD to examine how the presence of the microphase separated domains in the supercooled liquid influences the ability to form stable glasses. This model suggests that increasing molecule tail length results in decreased thermodynamic and kinetic stability of the molecules in PVD films. The reduced stability is further linked to the reduced ability of these molecules to equilibrate at the free surface during PVD. We find that as the tail length is increased, the relaxation time near the surface of the supercooled equilibrium liquid films of these molecules are slowed and become essentially bulk-like, due to the segregation of the fluorocarbon tails to the free surface. Surface diffusion is also markedly reduced due to clustering of the molecules at the surface. Based on these results, we propose a trapping mechanism where tails are unable to move between local phase separated domains on the relevant deposition time scales.
Desmana moschata
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Desmana
Desmana moschata

description: Desmana moschata (Linnaeus, 1758). Syst. Nat., 10th ed., 1:59. TYPE LOCALITY: U.S. S. R., " Russia aquosis." DISTRIBUTION: U.S. S. R.; Don, Volga, and S. Ural rivers and their tributaries; introduced into Tachan and Tartas rivers (Ob basin) and Dnepr River. ISIS NUMBER: 5301403006002001001.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
In silico study revealed the inhibitory activity of selected phytomolecules of C. rotundus against VacA implicated in gastric ulcer
Creators: name: Atanda, Halimat
name: Balogun, Toheeb Adewale
name: Alshehri, Mohammed M.
name: Olivos-Ramirez, Gustavo
name: Vilca-Quispe, Julissa
name: Chenet-Zuta, Manuel
name: Cárdenas-Cárdenas, Reyna
name: Wong, Henry Delgado
name: Ropón-Palacios, Georcki
name: Umar, Haruna Isiyaku
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Gastric ulcer is associated with weakening of the mucous coating of the stomach and damages to the intestinal lining. It is caused by H. pylori assisted by enzymes including VacA, which necessitates the need for inhibitors of VacA. Bioactive compounds from Cyperus rotundus have been documented to have anti-inflammatory activities. However, the mechanism of action of the phytochemicals is not characterized. This research aimed to assess, in silico, the potential of selected bioactive compounds against VacA based on the binding to its active sites. VacA and bioactive compounds structures were obtained from protein database and PubChem webserver, respectively. All compounds, including 2 controls, omeprazole and cimetidine were docked against the protein using AutoDock Vina and screened based on the binding energy. The selected complexes were subjected to pharmacokinetics and toxicity screening. Finally, molecular dynamics simulation and MMPBSA were carried out on two best compounds. 17 compounds interacted with the active site of VacA with higher binding affinities, with 7 of them – aureusidine, catechin, chlorogenic acid, isorhamnetin, isovitexin, oreintin, and vitexin having the best behaviours based on ADMET and druglikeness screening. Molecular dynamics and MMPBSA experiments of two of the hits corroborated good stability and binding energy for Ellagic Acid and Scirpusin B (ΔG = −14.38 and −13.20 kcal mol−1, respectively). These phytochemicals showed good pharmacokinetic profiles with respect to the control drugs. This study revealed that the identified compounds of C. rotundus may serve as VacA inhibitors and may be potent candidates for novel drug formulations in gastric ulcer treatment. Communicated by Ramaswamy H. Sarma
Additional file 1 of The effect of toxic leadership on workplace deviance: the mediating effect of emotional exhaustion, and the moderating effect of organizational cynicism
Creators: name: Ahmed, Asmaa Kamal
name: Atta, Mohamed Hussein Ramadan
name: El-Monshed, Ahmed Hashem
name: Mohamed, Alia Ibrahim
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Nutritional profile and food safety of raw and value-added food products of sorghum and millets in sub–Saharan Africa and South Asia
Creators: name: Musidzaramba, Tafadzwa J.
name: Mvumi, Brighton M.
name: Nyanga, Loveness K.
name: Kadzere, Irene
name: Kiboi, Milka
name: Mahlangu, Makhosi
name: Chingoma, Gracious
name: Mazula, Mgciniwethu
name: Macheka, Lesley
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: This study reviewed the nutritional composition and safety of sorghum, pearl, and finger millet in sub-Saharan Africa and South Asia, focusing on raw and value-added products. Using PRISMA guidelines, 35 peer-reviewed articles published between 2000 and 2023 were analysed. Data were extracted from Scopus, PubMed, and Google Scholar. Most studies (51.4%) were conducted between 2016 and 2020, with 53.3% focusing on macronutrients and 46.7% on micronutrients. Sorghum and millets were found to be rich in protein content ranging from 7.3% to 12.1% and carbohydrates exceeding 70%. Sorghum recorded the highest zinc levels (24.23 mg/kg), while finger millet had highest calcium content (344 mg/kg). Iron levels were significant in both grains, reaching 61.41 mg/kg in sorghum. Aflatoxin contamination ranged from 0.021 to 20.33 mg/kg, with microbial hazards reported in 83.3% of the studies. Fermentation was the most common processing method used to develop value-added products like porridge, beverages, and flour. Most of the studies on value-added products were from Zimbabwe (50%) and followed by India at 21.4%. This review highlights the potential of sorghum and millet to enhance nutrition and food security in drought-prone areas. However, research gaps remain on chemical and allergen hazards within the value chain, pointing to need for further studies.
Galemys Kaup 1829
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Galemys

description: Galemys Kaup, 1829. Skizz. Europ. Thierwelt, 1:119. ISIS NUMBER: 5301403006004000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
Galemys pyrenaicus
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Galemys
Galemys pyrenaicus

description: Galemys pyrenaicus (E. Geoffroy, 1811). Ann. Mus. Hist. Nat. Paris, 17: 193. TYPE LOCALITY: France, Hautes-Pyrenees, near Tarbes. DISTRIBUTION: Rivers of Pyrenees Mtns, of Spain and France; N.W. Spain and Portugal. ISIS NUMBER: 5301403006004001001.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
Order, intermittency and pressure fluctuations in a system of proliferating rods
Creators: name: Orozco-Fuentes, Sirio
name: Boyer, Denis
Publisher: name: arXiv
Year: 2013
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Tissues and Organs (q-bio.TO)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Non-motile elongated bacteria confined in two-dimensional open micro-channels can exhibit collective motion and form dense monolayers with nematic order if the cells proliferate, i.e., grow and divide. Using soft molecular dynamics simulations of a system of rods interacting through short range mechanical forces, we study the effects of the cell growth rate, the cell aspect ratio and of the sliding friction on nematic ordering and on pressure fluctuations in confined environments. Our results indicate that rods with aspect ratio >3.0 reach quasi-perfect nematic states at low sliding friction. At higher frictions, the global nematic order parameter shows intermittent fluctuations due to sudden losses of order and the time intervals between these bursts are power-law distributed. The pressure transverse to the channel axis can vary abruptly in time and shows hysteresis due to lateral crowding effects. The longitudinal pressure field is on average correlated to nematic order, but it is locally very heterogeneous and its distribution follows an inverse power-law, in sharp contrast with non-active granular systems. We discuss some implications of these findings for tissue growth.
description: 8 pages, 8 figures
Transmission statistics in nonconservative disordered optical medium
Creators: name: Lai, Zhong Yuan
name: Zaitsev, Oleg
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We determine the cumulants of electromagnetic energy transmitted through one-dimensional disordered medium with absorption or amplification. For this purpose we derive the Keldysh nonlinear sigma-model action with a source term that generates the energy current fluctuations. The fluctuations over the ensemble of disorder realizations are found to decrease (increase) with increasing absorption (amplification). In the conservative medium the fluctuations can be related to the Dorokhov's distribution of transmission coefficients.
description: 7 pages (v2: citations added)
Learning Achievement Handball Basic Skills by Student Teams Achievement Divisions (STAD) of Mathayomsuka 3 Students at Strisuksa School
Creators: name: Rattanaporn Kongpolprom
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Basic Skills for Handball
Collaborative (STAD)

description: Interdisciplinary Academic and Research Journal, 3, 4, 875-886
Mogera Pomel 1848
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Mogera

description: Mogera Pomel, 1848. Arch. Sci. Phys. Nat. Geneve, 9: 246. COMMENT: Formerly included in Talpa by Corbet, 1978:35; but see Imaizumi, 1970, The Handbook of Japanese Land Mammals, Vol. 1; Gureev, 1979:276.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
description: {"references": ["Gureev, A. A. 1979. Fauna SSSR, Mlekopitayutschie, tom. 4, vyp. 2. Nasekomoyadnye ... [Fauna of the USSR, Mammals, vol. 4, pt. 2. Insectivores (Mammalia, Insectivora)]. Nauka, Leningrad, 501 pp. (in Russian)."]}
Limits on violations of Lorentz Symmetry from Gravity Probe B
Creators: name: Bailey, Quentin G.
name: Everett, Ryan D.
name: Overduin, James M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Generic violations of Lorentz symmetry can be described by an effective field theory framework that contains both general relativity and the standard model of particle physics called the Standard-Model Extension (SME). We obtain new constraints on the gravitational sector of the SME using recently published final results from Gravity Probe B. These include for the first time an upper limit at the 10^(-3) level on the time-time component of the new tensor field responsible for inducing local Lorentz violation in the theory, and an independent limit at the 10^(-7) level on a combination of components of this tensor field.
description: 8 pages, 1 figure
The open LPC Paul trap for precision measurements in beta decay
Creators: name: Delahaye, P.
name: Ban, G.
name: Benali, M.
name: Durand, D.
name: Fabian, X.
name: Fléchard, X.
name: Herbane, M.
name: Liénard, E.
name: Mauger, F.
name: Méry, A.
name: Merrer, Y.
name: Naviliat-Cuncic, O.
name: Quéméner, G.
name: Retailleau, B. M.
name: Rodriguez, D.
name: Thomas, J. C.
name: Ujic, P.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The LPCTrap experiment uses an open Paul trap which was built to enable precision measurements in the beta decay of radioactive ions. The initial goal was the precise measurement of the beta-neutrino angular correlation coefficient in the decay of 6He. Its geometry results from a careful optimization of the harmonic potential created by cylindrical electrodes. It supersedes previously considered geometries that presented a smaller detection solid angle to the beta particle and the recoiling ion. We describe here the methods which were used for the potential optimization, and we present the measured performances in terms of trapping time, cloud size and temperature, and space charge related limits. The properties of the ion cloud at equilibrium are well reproduced by a simple numerical simulation using hard sphere collisions, which additionally gives insights on the trapping loss mechanism. The interpretation for the observed trapping liftetimes is further corroborated by a model recently developed for ion clouds in Paul traps. The open trap shall serve other projects. It is currently used for commissioning purpose in the TRAPSENSOR experiment and is also considered in tests of the Standard Model involving the beta decay of polarized $^{23}$Mg and $^{39}$Ca ion in the frame of the MORA experiment. The latter tests require in-trap polarization of the ions and further optimization of the trapping and detection setup. Based on the results of the simulations and of their interpretations given by the model, different improvements of the trapping setup are discussed.
description: 19 pages, 16 figures
Additional file 1 of Clinical and genetic characteristics of 100 consecutive patients with Birt-Hogg-Dubé syndrome in Eastern Chinese region
Creators: name: Hu, Daiju
name: Wang, Rui
name: Liu, Jinli
name: Chen, Xianmeng
name: Jiang, Xianliang
name: Xiao, Jun
name: Ryu, Jay H.
name: Hu, Xiaowen
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Supplement Table 1. Genetic Characterization and Clinical Phenotypes of 100 patients with Birt‑Hogg‑Dubé syndrome
A mathematical theory of semantic development in deep neural networks
Creators: name: Saxe, Andrew M.
name: McClelland, James L.
name: Ganguli, Surya
Publisher: name: arXiv
Year: 2018
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Neurons and Cognition (q-bio.NC)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: An extensive body of empirical research has revealed remarkable regularities in the acquisition, organization, deployment, and neural representation of human semantic knowledge, thereby raising a fundamental conceptual question: what are the theoretical principles governing the ability of neural networks to acquire, organize, and deploy abstract knowledge by integrating across many individual experiences? We address this question by mathematically analyzing the nonlinear dynamics of learning in deep linear networks. We find exact solutions to this learning dynamics that yield a conceptual explanation for the prevalence of many disparate phenomena in semantic cognition, including the hierarchical differentiation of concepts through rapid developmental transitions, the ubiquity of semantic illusions between such transitions, the emergence of item typicality and category coherence as factors controlling the speed of semantic processing, changing patterns of inductive projection over development, and the conservation of semantic similarity in neural representations across species. Thus, surprisingly, our simple neural model qualitatively recapitulates many diverse regularities underlying semantic development, while providing analytic insight into how the statistical structure of an environment can interact with nonlinear deep learning dynamics to give rise to these regularities.
Interpreting the Ionization Sequence in AGN Emission-Line Spectra
Creators: name: Richardson, Chris T.
name: Allen, James T.
name: Baldwin, Jack A.
name: Hewett, Paul C.
name: Ferland, Gary J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We investigate the physical cause of the great range in the ionization level seen in the spectra of narrow lined active galactic nuclei (AGN). Mean field independent component analysis identifies examples of individual SDSS galaxies whose spectra are not dominated by emission due to star formation (SF), which we designate as AGN. We assembled high S/N ratio composite spectra of a sequence of these AGN defined by the ionization level of their narrow-line regions (NLR), extending down to very low-ionization cases. We used a local optimally emitting cloud (LOC) model to fit emission-line ratios in this AGN sequence. These included the weak lines that can be measured only in the co-added spectra, providing consistency checks on strong line diagnostics. After integrating over a wide range of radii and densities our models indicate that the radial extent of the NLR is the major parameter in determining the position of high to moderate ionization AGN along our sequence, providing a physical interpretation for their systematic variation. Higher ionization AGN contain optimally emitting clouds that are more concentrated towards the central continuum source than in lower ionization AGN. Our LOC models indicate that for the objects that lie on our AGN sequence, the ionizing luminosity is anticorrelated with the NLR ionization level, and hence anticorrelated with the radial concentration and physical extent of the NLR. A possible interpretation that deserves further exploration is that the ionization sequence might be an age sequence where low ionization objects are older and have systematically cleared out their central regions by radiation pressure. We consider that our AGN sequence instead represents a mixing curve of SF and AGN spectra, but argue that while many galaxies do have this type of composite spectra, our AGN sequence appears to be a special set of objects with negligible SF excitation.
description: 57 pages; 18 figures, accepted by MNRAS
Mogera latouchei Thomas 1907
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Insectivora
Talpidae
Mogera
Mogera latouchei

description: Mogera latouchei Thomas, 1907. Proc. Zool. Soc. Lond., 1907:463. TYPE LOCALITY: China, Fukien, Kuatun, 3500 ft. (1067 m). DISTRIBUTION: S.E. China, Hainan Isl. COMMENT: Formerly included in Talpa micrura by Ellerman and Morrison-Scott, 1951:40; but see Corbet, 1978:33; Gureev, 1979:279.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Insectivora, pp. 58-106 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 102, DOI: 10.5281/zenodo.7353001
description: {"references": ["Ellerman, J. R., and T. C. S. Morrison-Scott. 1951. Checklist of Palaearctic and Indian mammals 1758 to 1946. Trustees of the British Museum (Natural History), London, 810 pp.", "Gureev, A. A. 1979. Fauna SSSR, Mlekopitayutschie, tom. 4, vyp. 2. Nasekomoyadnye ... [Fauna of the USSR, Mammals, vol. 4, pt. 2. Insectivores (Mammalia, Insectivora)]. Nauka, Leningrad, 501 pp. (in Russian)."]}
On the Regime of Localized Excitations for Disordered Oscillator Systems
Creators: name: Abdul-Rahman, Houssam
name: Sims, Robert
name: Stolz, Günter
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mathematical Physics (math-ph)
subject: Spectral Theory (math.SP)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 82B44

description: We study quantum oscillator lattice systems with disorder, in arbitrary dimension, requiring only partial localization of the associated effective one-particle Hamiltonian. This leads to a many-body localized regime of excited states with arbitrarily large energy density. We prove zero-velocity Lieb-Robinson bounds for the dynamics of Weyl operators as well as for position and momentum operators restricted to this regime. Dynamical localization is also shown in the form of quasi-locality of the time evolution of local Weyl operators and through exponential clustering of the dynamic correlations of states with localized excitations.
Learning Achievements on Handball Basic Skills through the Instructional Plan of Davie’s Practical Skill for Grade 6 Students at Anuban Maha Sarakham School
Creators: name: Kumpang Sritowpakdee
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Learning Achievements
Basic Skills for Handball
Public Media

description: Interdisciplinary Academic and Research Journal, 3, 4, 887-898
Diffuse interface models of locally inextensible vesicles in a viscous fluid
Creators: name: Aland, Sebastian
name: Egerer, Sabine
name: Lowengrub, John
name: Voigt, Axel
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences
subject: 35Q92

description: We present a new diffuse interface model for the dynamics of inextensible vesicles in a viscous fluid. A new feature of this work is the implementation of the local inextensibility condition in the diffuse interface context. Local inextensibility is enforced by using a local Lagrange multiplier, which provides the necessary tension force at the interface. To solve for the local Lagrange multiplier, we introduce a new equation whose solution essentially provides a harmonic extension of the local Lagrange multiplier off the interface while maintaining the local inextensibility constraint near the interface. To make the method more robust, we develop a local relaxation scheme that dynamically corrects local stretching/compression errors thereby preventing their accumulation. Asymptotic analysis is presented that shows that our new system converges to a relaxed version of the inextensible sharp interface model. This is also verified numerically. Although the model does not depend on dimension, we present numerical simulations only in 2D. To solve the 2D equations numerically, we develop an efficient algorithm combining an operator splitting approach with adaptive finite elements where the Navier-Stokes equations are implicitly coupled to the diffuse interface inextensibility equation. Numerical simulations of a single vesicle in a shear flow at different Reynolds numbers demonstrate that errors in enforcing local inextensibility may accumulate and lead to large differences in the dynamics in the tumbling regime and differences in the inclination angle of vesicles in the tank-treading regime. The local relaxation algorithm is shown to effectively prevent this accumulation by driving the system back to its equilibrium state when errors in local inextensibility arise.
description: 25 pages