cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Digital earth observation-based solution to improve monitoring and management actions for coastal water quality
Creators: name: Choo, Jenny Cheng Yi
Publisher: name: Swinburne
Year: 2024

description: To address the aims of improving the coastal water monitoring strategies in Sarawak, Malaysian Borneo, this thesis successfully demonstrated the application of digital earth-observation based approaches, which enables rapid detection of water quality changes over space and time. This outcome was made possible with the development of regional remote sensing model and applied onto time-series ocean colour satellite imageries for analysis. Ultimately, this thesis highlighted the impact and value of digital-based methods, in support of the Sustainable Development Goal 14 - Life Below Water, to provide rapid and informed-based decisions for the better management of the coastal ecosystem.
title: Síndrome de Persheron: lesiones talámicas bilaterales
Creators: name: Salinas Vela, Francisco Tomás
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Head and neck
subject: Neuroradiology brain
subject: MR
subject: MR-Diffusion/Perfusion
subject: Ischaemia / Infarction

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
La irrigación talámica proviene de variadas conexiones entre la arteria carótida interna y la arteria basilar.
Señalaremos la importancia de la arteria de Persheron en este territorio de vascularización complicada y variable ante cuadros...
Identification of A Novel Target in Nasopharyngeal Carcinoma for Therapeutic Application of Silvestrol
Creators: name: Daker, Maelinda
Publisher: name: Swinburne
Year: 2024

description: Nasopharyngeal carcinoma (NPC) is a cancer of the epithelial lining of the nasopharynx. Majority of NPC patients who have fully completed therapy eventually die. Treatment resistance and metastasis remain as clinical problems. Current treatment strategies merely control the disease, which may recur until treatment options runs out. Thus, it is imperative to discover new therapeutic strategies to improve treatment outcome. Silvestrol, a protein synthesis inhibitor, was evaluated for the treatment of NPC. Given that cancer cells require continuous expression of cancer-related proteins, interference with protein production can disrupt cancer cells; thus, opening a therapeutic window for protein synthesis inhibitors.
title: Gas Extraluminal Abdominal en Imagen: ABC para el radiólogo general.
Creators: name: Borrego Gómez, Jesús
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Biological effects
subject: Tissue characterisation
subject: Abscess
subject: Imaging sequences
subject: Diagnostic procedure
subject: Structured reporting
subject: CT
subject: Conventional radiography
subject: Emergency
subject: Education
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Ilustrar las principales causas de aire abdominal patológico y describir como se visualiza con las distintas técnicas de imagen. Conocer los procesos patológicos más habituales que se manifiestan con la presencia de gas anómalo y los contextos...
Rolling towards Radicalization : Right-Wing Populist Identification on Social Media During the 2022 Canadian Truckers’ Convoy
Creators: name: Hofmeister, Claire
Publisher: name: The University of British Columbia
Year: 2025

description: The scope of protests and political demonstrations have expanded beyond the physical environment, and are accessible through social media with live-streams, donation apps and comments. Social media facilitates remote participants to engage with those directly involved and on-site. This paper analyzes the case study of the 2022 Truckers’ convoy in Canada, and the effects of exposure to right-wing populist protest on political opinion. Social media was incorporated as a protest technique used throughout the Convoy occupation, used to amass widespread followings and online support (Zaiontz 2024). To investigate Convoy populism, I will use two large scale public opinion surveys of both Canadians and Albertans. In addition to survey data, content and keyword dictionary analysis are used to supplement the statistical models. Evidence is presented for the persuasive nature of social media Convoy discourses, where the findings suggest increased right-wing populist opinions among individuals on social media, with significant interaction effects in 2022.
title: Diagnóstico por imagen del atrapamiento femoroacetabular
Creators: name: Vicente, Mikel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Arthrography
subject: MR
subject: Conventional radiography
subject: Musculoskeletal soft tissue
subject: Musculoskeletal bone
subject: Musculoskeletal joint

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar la etiopatogenia del choque femoroacetabular (FAI). Discutir la utilidad de las técnicas de imagen,
los requisitos técnicos y las estrategias en el diagnóstico de esta patología. Describir los hallazgos radiológicos más frecuentes del...
Why less complexity produces better forecasts : An independent data evaluation of kelp habitat models
Creators: name: Gregr, Edward J.
name: Palacios, Daniel M.
name: Thompson, Allison
name: Chan, Kai Ming Adam, 1975-
Publisher: name: The University of British Columbia
Year: 2019

description: Understanding how species are distributed in the environment is increasingly important for natural resource management, particularly for keystone and habitat forming species, and those of conservation concern. Habitat suitability models are fundamental to developing this understanding; however their use in management continues to be limited due to often-vague model objectives and inadequate evaluation methods. Along the Northeast Pacific coast, canopy kelps {Macrocystis pyrifera and Nereocystis luetkeana) provide biogenic habitat and considerable primary production to nearshore ecosystems. We investigated the distribution of these species by examining a series of increasingly complex habitat suitability models ranging from process-based models based on species' ecology to complex Generalised Additive Models applied to purpose-collected survey data. Seeking limits on model complexity, we explored the relationship between model complexity and forecast skill, measured using both cross-validation and independent data evaluation. Our analysis confirmed the importance of predictors used in models of coastal kelp distributions developed elsewhere {i.e., depth, bottom type, bottom slope, and exposure); it also identified additional important factors including salinity, and interactions between exposure and salinity, and slope and tidal energy. Comparative results showed that cross-validation can lead to over-fitting, while independent data evaluation clearly identified the appropriate model complexity for generating habitat forecasts. Our results also illustrate that, depending on the evaluation data, predictions from simpler models can out-perform those from more complex models. Collectively, the insights from evaluating multiple models with multiple data sets contribute to the holistic assessment of model forecast skill. The continued development of methods and metrics for evaluating model forecasts with independent data, and the explicit consideration of model objectives and assumptions, promise to increase the utility of model forecasts to decision makers.
Constraint-based master scheduling problem.
Creators: name: Potter, Charles Michael.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Computer Science.

description: In the manufacturing industry, many problems pertain to part management, assembly and scheduling. Products today largely consist of a series of components which themselves can, in turn, consist of more components. The assembly of a product becomes an exercise in assembling all of the sub-components in a timely fashion. Sometimes these sub-components are available in stock, while other times, they must be manufactured using other sub-components. Thus, inventory management of these sub-components becomes crucial in the manufacturing of products on schedule. This thesis looks at the problem of managing inventory so as to maximize a profit function associated with customer orders whose ordered parts are assembled on time. Because this problem is known to be NP-hard, we propose efficient heuristic methods for this problem. Two of these methods are implemented and tested against each other.
title: Mesenteritis Esclerosante: espectro radiológico en la Tomografía Computarizada
Creators: name: Ramírez Ribelles, Carolina
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: CT
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
-El objetivo principal es analizar la semiología radiológica que nos podemos encontrar en la mesenteritis esclerosante,
mediante imágenes de TC. - Como objetivo secundario plantearemos un diagnostico diferencial en base a los hallazgos descritos...
The SAMI Galaxy Survey: The cluster redshift survey, target selection and cluster properties
Creators: name: Owers, M. S.
name: Allen, J. T.
name: Baldry, I.
name: Bryant, J. J.
name: Cecil, G. N.
name: Cortese, Luca
name: Croom, S. M.
name: Driver, S. P.
name: Fogarty, L. M. R.
name: Green, A. W.
name: Helmich, E.
name: de Jong, J. T. A.
name: Kuijken, K.
name: Mahajan, S.
name: McFarland, J.
name: Pracy, M. B.
name: Robotham, A. G. S.
name: Sikkema, G.
name: Sweet, Sarah
name: Taylor, Edward
name: Verdoes Kleijn, G.
name: Bauer, A. E.
name: Bland-Hawthorn, J.
name: Brough, S.
name: Colless, M.
name: Couch, Warrick
name: Davies, R. L.
name: Drinkwater, M. J.
name: Goodwin, M.
name: Hopkins, A. M.
name: Konstantopoulos, I. S.
name: Foster, C.
name: Lawrence, J. S.
name: Lorente, N. P. F.
name: Medling, A. M.
name: Metcalfe, N.
name: Richards, S. N.
name: van de Sande, J.
name: Scott, N.
name: Shanks, T.
name: Sharp, R.
name: Thomas, A. D.
name: Tonini, C.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: We describe the selection of galaxies targeted in eight low-redshift clusters (APMCC0917, A168, A4038, EDCC442, A3880, A2399, A119 and A85; 0.029 < z < 0.058) as part of the Sydney-AAO Multi-Object Integral field spectrograph Galaxy Survey (SAMI-GS). We have conducted a redshift survey of these clusters using the AAOmega multi-object spectrograph on the 3.9-m Anglo-Australian Telescope. The redshift survey is used to determine cluster membership and to characterize the dynamical properties of the clusters. In combination with existing data, the survey resulted in 21 257 reliable redshift measurements and 2899 confirmed cluster member galaxies. Our redshift catalogue has a high spectroscopic completeness (∼94 per cent) for rpetro ≤ 19.4 and cluster-centric distances R < 2R200. We use the confirmed cluster member positions and redshifts to determine cluster velocity dispersion, R200, virial and caustic masses, as well as cluster structure. The clusters have virial masses 14.25 ≤ log(M200/M⊙) ≤ 15.19. The cluster sample exhibits a range of dynamical states, from relatively relaxed-appearing systems, to clusters with strong indications of merger-related substructure. Aperture- and point spread function matched photometry are derived from Sloan Digital Sky Survey and VLT Survey Telescope/ATLAS imaging and used to estimate stellar masses. These estimates, in combination with the redshifts, are used to define the input target catalogue for the cluster portion of the SAMI-GS. The primary SAMI-GS cluster targets have R
title: Signos precoces de la angiopatía amiloide cerebral
Creators: name: Campos Álvarez, Carmen
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Blood
subject: Haemorrhage
subject: MR
subject: Neuroradiology brain

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describimos dos formas de presentación atípica de la angiopatía amiloide cerebral (AAC):la hemorragia subaracnoidea y la siderosis...
title: ¿Qué se esconde tras un nefrograma alterado?
Creators: name: Fernández, Ana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Kidney
subject: CT
subject: Image compression

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El objetivo es averiguar qué patología se esconde detrás de un nefrograma alterado,
destacando la correlación entre fisiopatología e...
Passive Entrapment of Tumor Cells Determines Metastatic Dissemination to Spinal Bone and Other Osseous Tissues
Creators: name: Broggini, Thomas
name: Piffko, Andras
name: Hoffmann, Christian J.
name: Harms, Christoph
name: Vajkoczy, Peter
name: Czabanka, Marcus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: During the metastatic process tumor cells circulate in the blood stream and are carried to various organs. In order to spread to different organs tumor cell—endothelial cell interactions are crucial for extravasation mechanisms. It remains unclear if tumor cell dissemination to the spinal bone occurs by passive entrapment of circulating tumor cells or by active cellular mechanisms mediated by cell surface molecules or secreted factors. We investigated the seeding of three different tumor cell lines (melanoma, lung and prostate carcinoma) to the microvasculature of different organs. Their dissemination was compared to biologically passive microbeads. The spine and other organs were resected three hours after intraarterial injection of tumor cells or microbeads. Ex vivo homogenization and fluorescence analysis allowed quantification of tumor cells or microbeads in different organs. Interestingly, tumor cell distribution to the spinal bone was comparable to dissemination of microbeads independent of the tumor cell type (melanoma: 5.646% ± 7.614%, lung: 6.007% ± 1.785%, prostate: 3.469% ± 0.602%, 7 μm beads: 9.884% ± 7.379%, 16 μm beads: 7.23% ± 1.488%). Tumor cell seeding differed significantly between tumor cells and microbeads in all soft tissue organs. Moreover, there were significant differences between the different tumor cell lines in their dissemination behaviour to soft tissue organs only. These findings demonstrate that metastatic dissemination of tumor cells to spinal bone and other osseous organs is mediated by passive entrapment of tumor cells similar to passive plugging of microvasculature observed after intraarterial microbeads injection.
title: Fusión de imágenes ECO-TC/RM en el diagnóstico y tratamiento de lesiones óseas: Nuevos horizontes para el radiólogo.
Creators: name: Iglesias Hidalgo, Gotzon
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Interventional non-vascular
subject: Musculoskeletal system
subject: Ultrasound
subject: CT-High Resolution
subject: MR
subject: Biopsy
subject: Equipment
subject: Neoplasia

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Demostrar la utilidad de la técnica de fusión (TF) ECO-TC/RM en las biopsias óseas,en el tratamiento ablativo de determinados tumores óseos y conocer sus ventajas respecto a las técnicas...
title: Tumores hepatobiliares en la infancia
Creators: name: Vargas Romero, Javier
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Ultrasound-Colour Doppler
subject: CT
subject: MR
subject: Paediatric
subject: Liver

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Conocer las manifestaciones radiologicas de los tumores hepatobiliares en...
The SAMI galaxy survey: a new method to estimate molecular gas surface densities from star formation rates
Creators: name: Federrath, Christoph
name: Salim, Diane M.
name: Medling, Anne M.
name: Davies, Rebecca
name: Yuan, Tiantian
name: Bian, Fuyan
name: Groves, Brent A.
name: Ho, I-Ting
name: Sharp, Robert
name: Kewley, Lisa J.
name: Sweet, Sarah
name: Richards, Samuel N.
name: Bryant, Julia J.
name: Brough, Sarah
name: Croom, Scott
name: Scott, Nicholas
name: Lawrence, Jon
name: Konstantopoulos, Iraklis
name: Goodwin, Michael
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: Stars form in cold molecular clouds. However, molecular gas is difficult to observe because the most abundant molecule (H2) lacks a permanent dipole moment. Rotational transitions of CO are often used as a tracer of H2, but CO is much less abundant and the conversion from CO intensity to H2 mass is often highly uncertain. Here we present a new method for estimating the column density of cold molecular gas (Σgas) using optical spectroscopy. We utilize the spatially resolved Hα maps of flux and velocity dispersion from the Sydney-AAO Multi-object Integral field spectrograph (SAMI) Galaxy Survey. We derive maps of Σgas by inverting the multi-freefall star formation relation, which connects the star formation rate surface density (ΣSFR) with Σgas and the turbulent Mach number ( M ). Based on the measured range of ΣSFR = 0.005– 1.5M⊙yr−1kpc−2 and M=18 –130, we predict Σgas = 7– 200M⊙pc−2 in the star-forming regions of our sample of 260 SAMI galaxies. These values are close to previously measured Σgas obtained directly with unresolved CO observations of similar galaxies at low redshift. We classify each galaxy in our sample as ‘star-forming’ (219) or ‘composite/AGN/shock’ (41), and find that in ‘composite/AGN/shock’ galaxies the average ΣSFR, M and Σgas are enhanced by factors of 2.0, 1.6 and 1.3, respectively, compared to star-forming galaxies. We compare our predictions of Σgas with those obtained by inverting the Kennicutt–Schmidt relation and find that our new method is a factor of 2 more accurate in predicting Σgas, with an average deviation of 32 per cent from the actual Σgas.
Brucellosis in a refugee who migrated from Syria to Germany and lessons learnt, 2016
Creators: name: Grunow, R.
name: Jacob, D.
name: Klee, S.
name: Schlembach, D.
name: Jackowski-Dohrmann, S.
name: Loenning-Baucke, V.
name: Eberspächer, B.
name: Swidsinski, S.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: A teenage woman migrating from Syria arrived in May 2015 in Germany. She gave birth to a healthy child in early 2016, but became febrile shortly after delivery. Blood cultures revealed Brucella melitensis. In retrospect, she reported contact with sheep in Syria and recurrent pain in the hip joints over about five months before diagnosis of brucellosis. We discuss consequences for adequate treatment of mother and child as well as for clinical and laboratory management.
Measuring the Dissipation Rate of Turbulent Kinetic Energy in Strongly Stratified, Low-Energy Environments : A Case Study From the Arctic Ocean
Creators: name: Scheifele, Benjamin
name: Waterman, Stephanie
name: Merckelbach, Lucas
name: Carpenter, Jeffrey R.
Publisher: name: The University of British Columbia
Year: 2019

description: We compare estimates of the turbulent dissipation rate, 𝜖, obtained independently from coincident measurements of shear and temperature microstructure in the southeastern Beaufort Sea, a strongly stratified, low-energy environment. The measurements were collected over 10 days in 2015 by an ocean glider equipped with microstructure instrumentation; they yield 28,575 shear-derived and 21,577 temperature-derived 𝜖 estimates. We find agreement within a factor of 2 from the two types of estimates when 𝜖 exceeds 3 × 10−¹¹ W/kg, a threshold we identify as the noise floor of the shear-derived estimates. However, the temperature-derived estimates suggest that the dissipation rate is lower than this threshold in 58% of our observations. Further, the noise floor of the shear measurements artificially skews the statistical distribution of 𝜖 below 10−¹⁰ W/kg, that is, in 70% of our observations. The shear measurements overestimate portions of the geometric mean vertical profile of 𝜖 by more than an order of magnitude and underestimate the overall variability of 𝜖 by at least 2 orders of magnitude. We further discuss uncertainties that arise in both temperature- and shear-derived 𝜖 estimates in strongly stratified, weakly turbulent conditions, and we demonstrate how turbulence spectra are systematically modified by stratification under these conditions. Using evidence from the temperature-gradient spectral shapes and from the observed 𝜖 distributions, we suggest that the temperature-derived dissipation rates are reliable to values as small as 2 × 10−¹² W/kg, making them preferable for characterizing the turbulent dissipation rates in the weakly turbulent environment of this study. The data may be downloaded at doi:10.14288/1.0368671.
title: Magnetotellurik zur Identifizierung von tektonisch verursachten Aenderungen des elektrischen Widerstandes
title: Modellierungen und neue Methoden der Auswertung
titleType: Subtitle
title: ein Beitrag zum Deutsch-Tuerkischen Erdbeben-Forschungsprojekt
titleType: Subtitle
Creators: name: Mueller, Andreas
Publisher: name: Deutsches GeoForschungsZentrum GFZ
Year: 2012

description: Scientific Technical Report; 97/18; ISSN 1610-0956
Frontal Ground Plane Checking with Single LiDAR Range Finder-based Wearable Model
Creators: name: Chai, Aylwin Bing Chun
Publisher: name: Swinburne
Year: 2024

description: Assistive technologies have been an ongoing research area to help with orientation, wayfinding, obstacle detection, object and people recognition. However, there is a lack of a single consolidated electronic-based system that can detect and forewarn changes in the frontal ground plane conditions. This research aimed to identify an effective approach in checking the ground plane which is one of the five travel functions for humans. This thesis presented a comprehensive literature survey of the existing electronic-based technologies, the design and development of the proposed wearable model, and the testing and evaluation to prove its potential in frontal ground plane checking.
Dust properties across the Co snowline in the HD 163296 disk from ALMA and VLA observations
Creators: name: Guidi, G.
name: Tazzari, M.
name: Testi, L.
name: De Gregorio-Monsalvo, I.
name: Chandler, C. J.
name: Pérez, L.
name: Isella, A.
name: Natta, A.
name: Ortolani, S.
name: Henning, Th
name: Corder, S.
name: Linz, H.
name: Andrews, S.
name: Wilner, D.
name: Ricci, L.
name: Carpenter, J.
name: Sargent, A.
name: Mundy, L.
name: Storm, S.
name: Calvet, N.
name: Dullemond, C.
name: Greaves, J.
name: Lazio, J.
name: Deller, Adam
name: Kwon, W.
Publisher: name: Swinburne
Year: 2024

description: Context. To characterize the mechanisms of planet formation it is crucial to investigate the properties and evolution of protoplanetary disks around young stars, where the initial conditions for the growth of planets are set. The high spatial resolution of Atacama Large Millimeter/submillimeter Array (ALMA) and Karl G. Jansky Very Large Array (VLA) observations now allows the study of radial variations of dust properties in nearby resolved disks and the investigation of the early stages of grain growth in disk midplanes. Aims. Our goal is to study grain growth in the well-studied disk of the young, intermediate-mass star HD 163296 where dust processing has already been observed and to look for evidence of growth by ice condensation across the CO snowline, which has already been identified in this disk with ALMA. Methods. Under the hypothesis of optically thin emission, we compare images at different wavelengths from ALMA and VLA to measure the opacity spectral index across the disk and thus the maximum grain size. We also use a Bayesian tool based on a two-layer disk model to fit the observations and constrain the dust surface density. Results. The measurements of the opacity spectral index indicate the presence of large grains and pebbles (≥1 cm) in the inner regions of the disk (inside ~50 AU) and smaller grains, consistent with ISM sizes, in the outer disk (beyond 150 AU). Re-analyzing ALMA Band 7 science verification data, we find (radially) unresolved excess continuum emission centered near the location of the CO snowline at ~90 AU. Conclusions. Our analysis suggests a grain size distribution consistent with an enhanced production of large grains at the CO snowline and consequent transport to the inner regions. Our results combined with the excess in infrared scattered light suggests there is a structure at 90 AU involving the whole vertical extent of the disk. This could be evidence of small scale processing of dust at the CO snowline.
Effects of Poly(ADP-Ribose) Polymerase-1 Inhibition in a Neonatal Rodent Model of Hypoxic-Ischemic Injury
Creators: name: Klöfers, Melanie
name: Kohaut, Jules
name: Bendix, Ivo
name: Herz, Josephine
name: Boos, Vinzenz
name: Felderhoff-Mueser, Ursula
name: Dzietko, Mark
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background. Hypoxia ischemia (HI) to the developing brain occurs in 1–6 in 1000 live births. Large numbers of survivors have neurological long-term sequelae. However, mechanisms of recovery after HI are not understood and preventive measures or clinical treatments are not effective. Poly(ADP-ribose) polymerase-1 is overactivated in response to ischemia. In neonatal mice HI activates PARP-1 but its role in perinatal brain injury remains uncertain. Objective. Aim of this study was to explore the effect of TES448 (PARP-1-inhibitor) and hypothermia after an ischemic insult. Design and Methods. 10-day-old Wistar rats underwent HI. TES448 was given 10 min, 3 hrs, and 6 hrs after hypoxia. Hypothermia was started 30 min after HI and brains were dissected at P12. Western blotting and histological staining were used to evaluate for degree of injury. Results. Protein expression of PARP-1 levels was diminished after TES448 treatment. Cresyl violet and TUNEL staining revealed decreased injury in male rat pups following TES448 and combined treatment. Female rats showed increased numbers of TUNEL-positive cells after combined therapy. TES448 inhibited microglia activation after hypoxic-ischemic injury. A cellular response including NeuN, Olig2, and MBP was not affected by PARP-1-inhibition. Conclusions. Inhibition of PARP-1 and hypothermia lead to an alteration of injury but this effect is sexually dimorphic.
Less functional variants of TLR-1/-6/-10 genes are associated with age
Creators: name: Hamann, Lutz
name: Kupcinskas, Juozas
name: Almanza, Luis C. Berrocal
name: Skieceviciene, Jurgita
name: Franke, Andre
name: Nöthlings, Ute
name: Schumann, Ralf R.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: Inflamm-aging
subject: Innate immunity
subject: Toll-like receptors
subject: Polymorphisms
subject: Healthy aging
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background Determining the prerequisites for healthy aging is a major task in the modern world characterized by a longer lifespan of the individuals. Besides lifestyle and environmental influences genetic factors are involved as shown by several genome-wide association studies. Older individuals are known to have an impaired immune response, a condition recently termed “inflamm- aging”. We hypothesize that the induction of this condition in the elderly is influenced by the sensitivity of the innate immune system. Therefore, we investigated genetic variants of the Toll-like receptor (TLR) family, one of the major family of innate immune receptors, for association with age in two cohorts of healthy, disease-free subjects. Results According to sex we found a positive association of loss-of-function variants of TLR-1 and −6 with healthy aging with odds ratios of 1.54 in males for TLR-6 (249 S/S), and 1.41, 1.66, and 1.64 in females for TLR-1 prom., TLR-1 (248 S/S), and TLR-1 (602 S/S), respectively. Thus, the presence of these variants increases the probability of achieving healthy old age and indicates that a reduced TLR activity may be beneficial in the elderly. Conclusions This is the first report showing an association of TLR variants with age. While a loss of function of an important immune receptor may be a risk factor for acute infections as has been shown previously, in the setting of healthy ageing it appears to be protective, which may relate to “inflamm-aging”. These first results should be reproduced in larger trials to confirm this hypothesis.
Made in China: Dancing Through the Transracial Adoption Experience
Creators: name: Sheehan, Abby
Publisher: name: Zenodo
Year: 2024
Subjects: adoption
transracial
transnational
dance
identity
Chinese American

description: In the face of a dramatic population increase, China implemented the one-child policy in 1979. Due to deep-rooted patriarchy and male superiority in China, many female babies were aborted, killed, or placed for transnational adoption. There is a lot of information about the history of this policy. However, there is less emphasis on what happened to the baby girls from China who were placed in orphanages to be adopted. This research project seeks to privilege the stories of adoptees by exploring the experiences and identities of Chinese transracial and transnational adoptees growing up under different-race parents in the United States. I interviewed five transracial and transnational adoptees who shared their stories, including common themes of marginalization and belonging, racial identity, and cultural identity. I translated research from the literature and material from the interviews in a live dance performance as an interpretation of the adoptee experience through movement and music. The dance opens with a poem I wrote about my adoption story, followed by a piece on the “red string of fate” that connects lovers and represents adoptees' unbreakable but tangled connection to China and America. The upbeat, fast-paced final section's movement highlights the door opening to many opportunities and, most importantly, finding family through adoption.
Ending world poverty: The elusive goal of the United Nations Development Programme.
Creators: name: Nelson, David.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Political Science, International Law and Relations.

description: Growing world poverty is a paramount problem for international development assistance organizations. Substantial multilateral funding, coupled with decades of development assistance activity, has done little to reduce poverty in the less developed countries. Globalized market-led development continues to be the conventional approach towards the resolution of this problem. This thesis argues that the United Nations Development Programme's (UNDP) promotion of the globalization discourse and its adherence to a market-led development philosophy and practice have restricted its ability to effectively reduce world poverty. Rooted historically in the establishment and maintenance of the post-war hegemonic world order, the UNDP represents part of the institutional framework that was designed to protect and advance Western economic and political interests. This paper employs discourse analysis to evaluate the UNDP's response to two specific world order crises--the first in 1975 and the second in 1990. The thesis also uses a method of critical analysis in order to isolate and analyze points of contradiction within the discourse/project orientation of the UNDP. Thus, by questioning and critically exposing the UNDP's adherence to a market-led development approach, this thesis will systematically deconstruct the UNDP's discourse thereby revealing the otherwise disguised power relationships revolving within and around the organization.
Lokale Wärme-Kältenetze (Factsheet)
Creators: name: NEFI New Energy for Industry
Publisher: name: NEFI
Year: 2024
Subjects: NEFI
Innovationsnetzwerk
Energie
Industrie
New Energy for Industry
Klima- und Energiefonds
Vorzeigeregion
Gemeinde
Regional

description: Ein lokales Wärme-Kältenetz bietet Kommunen zahlreiche Vorteile. Es ermöglicht eine effiziente und umweltfreundliche Nutzung von Energie, was wiederum zur Reduktion des CO₂-Ausstoßes beiträgt. Bei der Gestaltung solcher Netze liegt der Fokus auf der optimalen Wechselwirkung aller beteiligten Komponenten in Bezug auf Hydraulik und Thermodynamik.

Um dies zu erreichen, haben wir ein dynamisches Simulationstool entwickelt, das thermo-hydraulische Prozesse miteinander verknüpft. Dieses Tool hilft bei der Dimensionierung sämtlicher Komponenten und deren Wechselwirkung mit dem Wärmenetz.
Déficit de l'attention/hyperactivité et hausse du niveau d'activation cérébrale à l'aide d'une technique subliminale auditive.
Creators: name: Dupont, François.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Psychology, Clinical.

description: Certains déficits de l'attention/hyperactivité sont associés à une activité anormalement élevée des ondes cérébrales thêta combinée à un ralentissement de l'activité bêta. Conséquemment, certains traitements visent la réduction des ondes thêta et l'augmentation des ondes bêta. Un enregistrement subliminal auditif qui semble réduire l'activité thêta (Sub/Alpha) a récemment été développé et testé de façon préliminaire au niveau clinique. Ce traitement présent, l'avantage d'être facile à insérer dans les activités quotidiennes et il offre ainsi la possibilité d'être incorporé à des approches multi-modales déjà établies. De plus, il s'avère être trés économique. Notre étude a comparé l'efficacité de Sub/Alpha à celle d'un enregistrement de bruit rose, tous deux utilisés quotidiennement pendant cinq semaines (n = 11 pour chaque groupe). Un électro-encéphalogramme et un test sur ordinateur de la capacité d'attention, le Test of Variables of Attention (TOVA), ont été administrés à sept reprises. Il y avait une semaine d'intervalle entre les mesures. Les résultats démontrent une différence significative sur les mesures de thêta, bêta1 et du ratio T/B, pendant la présentation de Sub/Alpha comparée à celle du bruit rose. On ne remarque aucune différence significative entre l'écoute de Sub/Alpha et du bruit rose à la maison, sur les mesures de thêta, bêta1 et du ratio T/B, à moyen terme. Les résultats n'indiquent pas de différence significative sur les mesures du TOVA (omission, commission, temps de réponse et variabilité du temps de réponse), pendant la présentation de Sub/Alpha comparée à celle du bruit rose. Et finalement, on ne remarque aucune différence significative entre l'écoute de Sub/Alpha et du bruit rose à la maison, sur les mesures du TOVA à moyen terme. Pour les deux groupes il n'y a pas de changement entre la premiére et la derniére session de l'étude.
Exploring the learning outcomes of flipped learning in a Second Language (L2) academic writing classroom for low proficiency pre-university students
Creators: name: Lee, Rebecca Su Ping
Publisher: name: Swinburne
Year: 2024

description: This study explored how flipped classroom can enhance second language (L2) students' writing despite their low English proficiency and the shortage of time to bridge the English gap. Results revealed that the flipped group outperformed the control group in writing significantly. Students favoured the greater time preparation, the immediate feedback as well as the increased practice, interaction, motivation and self-efficacy. This study has successfully contributed to the literature by expanding the application of flipped classroom approach to L2 writing research. It has also subsequently proposed a Flipped Writing Framework that can be applied to other intensive language learning environments.
‘I’m on the train and I can’t stop it’: Western Canadians’ reactions to prediabetes and the role of self-compassion
Creators: name: Strachan, Shaelyn
name: Bean, Corliss
name: Jung, Mary E.
Publisher: name: Wiley Online
Year: 2019

description: Prediabetes, a condition characterized by impaired glucose regulation, is on the rise worldwide. This condition puts people at risk for cardiovascular disease and 50% of people with prediabetes will develop type 2 diabetes (T2D). People with prediabetes can reduce their risk of developing T2D through lifestyle changes such as regular physical activity and healthy eating. However, the experience of health risks can be associated with negative reactions that can undermine people’s ability to self-regulate the health behaviours that would reduce their health risk. Self-compassion, or treating oneself kindly in the face of challenge, is known to help people manage negative emotions and facilitate self-regulation. Therefore, self-compassion may be helpful for people with prediabetes who have to manage their health behaviours in the context of a health threat. The purpose of this study was to explore how people, from a small Canadian city who learn that they have prediabetes, react emotionally to their prediabetes diagnosis. We also explored participants’ receptivity to applying self-compassion in the context of their prediabetes. Twenty-one adults recently notified by their doctors as having HbA1c scores indicative of prediabetes (Mage=57.76, SD=5.43) engaged in a semi-structured interview between June 2017 and January 2018. Inductive thematic analysis was used to analyze the data. Four themes emerged. Participants’ reactions to learning that they had prediabetes were characterized by (a) distress and concern, (b) downplay of T2D risks, (c) guilt and shame, and participants were receptive to (d) self-compassion as a beneficial approach to take in relation to their prediabetes. Findings suggest that people experience negative reactions to their prediabetes diagnosis yet are receptive to self-compassion, which could mitigate these reactions. These findings can inform lifestyle behaviour change programs for individuals living with prediabetes by providing a better understanding of the patients’ perspectives of disease diagnosis.
Introduction of a novel pressure index to estimate the water distribution systems pipe burst rate based on historical data
Creators: name: Pour Akbarkhiavi, Savalan
Publisher: name: Swinburne
Year: 2024

description: One of the primary causes of pipe bursts in water distribution systems (WDS) is high water pressure within the pipe networks. The pipe renewal activity is an expensive practice for water authorities. Therefore, an accurate prediction for the number of pipe bursts within the WDS can contribute to efficient budget planning. This research introduces a new methodology to estimate the number of pipe bursts for the future WDS population growth. The introduced methodology could benefit the society through more planned and accurate operational and maintenance budget expenditure.
“She-cession” : Examining the Causes of the Gendered Effects of the 1997 Korean Financial Crisis
Creators: name: Johnston, Rin
Publisher: name: The University of British Columbia
Year: 2025

description: Despite the extensive body of research on the economic impacts of the 1997 Asian Financial Crisis, the role of traditional gender beliefs in shaping employment outcomes for women has remained underexplored. In this thesis, I argue that regional variations in neo-Confucian gender norms significantly influenced the extent to which women in South Korea were disproportionately impacted by job losses during and after the crisis. I propose that regions with stronger traditional gender beliefs faced more severe negative employment outcomes for women, as these beliefs hindered efforts to advance gender equality in the labor market. To test this argument, I combine employment data from 1989 to 2005 with a regional index of traditional gender beliefs created from World Value Survey results. Using regression analyses, I examine the relationship between gender beliefs and employment outcomes across various regions. The results demonstrate that regions with stronger traditional gender norms saw a significant increase in gender disparities in employment post-crisis. This study contributes to the literature on gender, economics, and cultural norms, offering new insights into how traditional gender beliefs intersect with economic crises and affect marginalized groups.
The LOFAR Two-metre Sky Survey: I. Survey description and preliminary data release
Creators: name: Shimwell, T. W.
name: Röttgering, H. J.A.
name: Best, P. N.
name: Williams, W. L.
name: Dijkema, T. J.
name: De Gasperin, F.
name: Hardcastle, M. J.
name: Heald, G. H.
name: Hoang, D. N.
name: Horneffer, A.
name: Intema, H.
name: Mahony, E. K.
name: Mandal, S.
name: Mechev, A. P.
name: Morabito, L.
name: Oonk, J. B.R.
name: Rafferty, D.
name: Retana-Montenegro, E.
name: Sabater, J.
name: Tasse, C.
name: Van Weeren, R. J.
name: Brüggen, M.
name: Brunetti, G.
name: Chy, K. T.
name: Conway, J. E.
name: Haverkorn, M.
name: Jackson, N.
name: Jarvis, M. J.
name: McKean, J. P.
name: Miley, G. K.
name: Morganti, R.
name: White, G. J.
name: Wise, M. W.
name: Van Bemmel, I. M.
name: Beck, R.
name: Brienza, M.
name: Bonafede, A.
name: Calistro Rivera, G.
name: Cassano, R.
name: Clarke, A. O.
name: Cseh, D.
name: Deller, Adam
name: Drabent, A.
name: Van Driel, W.
name: Engels, D.
name: Falcke, H.
name: Ferrari, C.
name: Fröhlich, S.
name: Garrett, M. A.
name: Harwood, J. J.
name: Heesen, V.
name: Hoeft, M.
name: Horellou, C.
name: Israel, F. P.
name: Kapińska, A. D.
name: Kunert-Bajraszewska, M.
name: McKay, D. J.
name: Mohan, N. R.
name: Orrú, E.
name: Pizzo, R. F.
name: Prandoni, I.
name: Schwarz, D. J.
name: Shulevski, A.
name: Sipior, M.
name: Smith, D. J.B.
name: Sridhar, S. S.
name: Steinmetz, M.
name: Stroe, A.
name: Varenius, E.
name: Van Der Werf, P. P.
name: Zensus, J. A.
name: Zwart, J. T.L.
Publisher: name: Swinburne
Year: 2024

description: The LOFAR Two-metre Sky Survey (LoTSS) is a deep 120–168 MHz imaging survey that will eventually cover the entire northern sky. Each of the 3170 pointings will be observed for 8 h, which, at most declinations, is sufficient to produce ~5″ resolution images with a sensitivity of ~100 μJy/beam and accomplish the main scientific aims of the survey, which are to explore the formation and evolution of massive black holes, galaxies, clusters of galaxies and large-scale structure. Owing to the compact core and long baselines of LOFAR, the images provide excellent sensitivity to both highly extended and compact emission. For legacy value, the data are archived at high spectral and time resolution to facilitate subarcsecond imaging and spectral line studies. In this paper we provide an overview of the LoTSS. We outline the survey strategy, the observational status, the current calibration techniques, a preliminary data release, and the anticipated scientific impact. The preliminary images that we have released were created using a fully automated but direction-independent calibration strategy and are significantly more sensitive than those produced by any existing large-area low-frequency survey. In excess of 44 000 sources are detected in the images that have a resolution of 25″, typical noise levels of less than 0.5 mJy/beam, and cover an area of over 350 square degrees in the region of the HETDEX Spring Field (right ascension 10h45m00s to 15h30m00s and declination 45°00′00″ to 57°00′00″).
Cost-effectiveness of human papillomavirus vaccination in Germany
Creators: name: Damm, Oliver
name: Horn, Johannes
name: Mikolajczyk, Rafael T.
name: Kretzschmar, Mirjam E. E.
name: Kaufmann, Andreas M.
name: Delere, Yvonne
name: Ultsch, Bernhard
name: Wichmann, Ole
name: Krämer, Alexander
name: Greiner, Wolfgang
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: HPV
subject: Vaccination
subject: Economic evaluation
subject: Cost-effectiveness
subject: Dynamic transmission mode
subject: l Germany
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background The aim of this study was to assess the cost-effectiveness of human papillomavirus (HPV) vaccination in addition to the current cervical cancer screening programme in Germany using a dynamic transmission model. Methods Based on a mathematical model simulating the transmission dynamics and the natural history of HPV infection and associated diseases (cervical intraepithelial neoplasia, cervical cancer, and genital warts), we estimated the epidemiological and economic consequences of HPV vaccination with both the quadrivalent and bivalent vaccines. In our base case analysis, we assessed the cost-effectiveness of vaccinating 12-year-old girls with a 3-dose schedule. In sensitivity analysis, we also evaluated the use of a 2-dose schedule and assessed the impact of vaccinating boys. Results From a health care payer perspective, incremental cost-effectiveness ratios (ICERs) of a 3-dose schedule were €34,249 per quality-adjusted life year (QALY) for the bivalent and €14,711 per QALY for the quadrivalent vaccine. Inclusion of indirect costs decreased ICERs by up to 40%. When adopting a health care payer perspective, ICERs of a 2-dose approach decreased to €19,450 per QALY for the bivalent and to €3645 per QALY for the quadrivalent vaccine. From a societal perspective, a 2-dose approach using the quadrivalent vaccine was a cost-saving strategy while using the bivalent vaccine resulted in an ICER of €13,248 per QALY. Irrespective of the perspective adopted, additional vaccination of boys resulted in ICERs exceeding €50,000 per QALY, except for scenarios with low coverage (20%) in girls. Conclusions Our model results suggest that routine HPV vaccination of 12-year-old girls with three doses is likely to be cost- effective in Germany. Due to the additional impact on genital warts, the quadrivalent vaccine appeared to be more cost-effective than the bivalent vaccine. A 2-dose schedule of the quadrivalent vaccine might even lead to cost savings when adopting a societal perspective. The cost-effectiveness of additional vaccination of boys was highly dependent on the coverage in girls.
In vacuo glycation of enzymes: A novel approach for increasing enzyme stability
Creators: name: Ewing, Erin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Chemistry, Biochemistry.

description: A novel approach for the thermostabilization of proteins was investigated. It is well established that proteins that are naturally highly glycosylated show an increased resistance to inactivation at high temperatures. However, non-enzymatic attachment of carbohydrate to proteins, otherwise known as protein glycation, under aqueous conditions is very difficult and has not been used as a general approach for increasing the thermostability of proteins. In the present study, advantage was taken of the in vacuo protein glycation procedure recently developed by Kaplan and his co-workers by which proteins can be extensively glycated in the absence of water and chemical reagents. In this procedure, reducing sugars react with the epsilon-amino groups of lysine side-chains to form a stable ketoamine derivative. The primary objective of the research presented in this thesis, was to determine the extent to which the thermostability of proteins can be increased by in vacuo glycation with reducing monosaccharides such as glucose. Another objective of this study was to investigate possible practical applications of this thermostabilization technology. (Abstract shortened by UMI.)