Progressive resisted exercise program combined with aerobic exercise on osteoporotic systemic lupus erythematous patients: a prospective randomized controlled trial
Creators: name: Eladl, Hadaya Mosaad
name: Abdel-Aal, Nabil Mahmoud
name: Ali, Khadra Mohamed
name: Elimy, Doaa Ayoub
name: Allam, Nesma M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine

description: To investigate the effect of progressive resisted exercise (PRE) and aerobic exercise (AE) on bone mineral density (BMD), muscular strength, exercise capacity, and health related quality of life (HRQoL) in patients with osteoporotic systemic lupus erythematous (SLE). This study was a single blinded randomized controlled trail. Eighty SLE participants, 30–50 years old, were randomly allocated into four equal groups. Group A received PRE and AE, group B received AE, group C received PRE, and group D received traditional medical treatment only. The intervention was implemented three days/week for six months. BMD was measured by Dual Energy X-ray Absorptiometry, muscle strength was measured by an isokinetic device, exercise capacity was measured by 6-min walk test, and HRQoL was measured by short form 36(SF-36). Every outcome was assessed at baseline, six months, and nine months. There were statistically significant differences among the groups in knee muscle strength, exercise capacity, and HRQol after 6 months (<i>p</i> &lt; 0.05) in favor of the combined group. BMD increased significantly in the combined and PRE groups compared to the AE and control groups (<i>p</i> &lt; 0.05). PRE combined with AE were more beneficial than either exercise alone in improving knee muscle strength, exercise capacity, and HRQoL. Rehabilitation professionals should implement combined aerobic and progressive resisted exercise programs as an effective strategy for improving bone mineral density, muscular strength, exercise capacity, and health-related quality of life in patients with osteoporotic systemic lupus erythematosus (SLE).Aerobic and resistance training should be tailored to address the specific needs of SLE patients to enhance musculoskeletal health and reduce the risk of fractures while considering the safety and disease activity of the individual.Combined aerobic and progressive resisted exercise provides a safe, non-pharmacological adjuvant therapy for managing osteoporosis in SLE patients, reducing dependence on medications with potential side effects Rehabilitation professionals should implement combined aerobic and progressive resisted exercise programs as an effective strategy for improving bone mineral density, muscular strength, exercise capacity, and health-related quality of life in patients with osteoporotic systemic lupus erythematosus (SLE). Aerobic and resistance training should be tailored to address the specific needs of SLE patients to enhance musculoskeletal health and reduce the risk of fractures while considering the safety and disease activity of the individual. Combined aerobic and progressive resisted exercise provides a safe, non-pharmacological adjuvant therapy for managing osteoporosis in SLE patients, reducing dependence on medications with potential side effects