cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Does higher education hone cognitive functioning and learning efficacy? Findings from a large, representative sample
Creators: name: Belen Guerra-Carrillo
name: Kiefer Katovich
name: Bunge, Silvia A.
Publisher: name: figshare
Year: 2016
Subjects: subject: 179999 Psychology and Cognitive Sciences not elsewhere classified
subject: FOS: Psychology

description: An implied goal of education is to provide enriching experiences that enhance domain-general abilities important for learning, such as keeping relevant information in mind, responding flexibly in accordance with task goals, and tackling novel problems. Here we examined, retrospectively and prospectively, the relationship between educational attainment and both cognitive performance and learning. We analyzed an existing dataset of cognitive test results from 196,388 subscribers to an online cognitive training program, Lumosity. These subscribers, ages 15-60, reported a wide range of educational attainment. Controlling for multiple variables, we found that higher levels of education were associated with better cognitive performance across the age range. Differences were large between Ph.D. vs. Some High School (d = .80), and moderate for Bachelor’s degree vs. High School (d = .51). Cognitive performance did not differ at age 17 between students who had vs. had not begun a college degree at that point, but was 0.5 SD higher at age 25 for college graduates than high school graduates. This and other such findings suggest a divergence in cognitive trajectories as a result of cumulative life experiences. In addition to measuring cognitive performance at one timepoint, we measured change in performance for 69,202 subscribers who had completed approximately 100 days of cognitive training. Higher educational attainment was associated with bigger gains, but the effect was small (d = .04 - .37). These results highlight the long-lasting trace of an effect of prior cognitive challenges, but also show that this effect can be reduced with additional experience.
Локализация объектов промышленного назначения на круговой экваториальной околоземной орбите
Creators: name: Юницкий А.Э.
name: Кушниренко А.В.
name: Кулик Е.Н.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: космическое индустриальное ожерелье «Орбита» (КИО «Орбита»)
космическая индустриализация
экономическая модель
мультипликаторы
устойчивое развитие
пеносталь
композитные материалы
кристаллы
микросхемы

description: Вопрос локализации новых промышленных объектов или переноса текущих технологических процессов на круговую экваториальную околоземную орбиту потребует от производственных компаний принятия долгосрочных стратегических решений. Их реализация затронет все стороны многих бизнесов. В статье раскрываются особенности авторского методического подхода, который позволяет выбирать наиболее рациональное направление в области размещения технологических процессов на околоземном пространстве ближнего космоса. Предлагаемая методика основана на использовании мультипликаторов, охватывающих диверсифицированные элементы бизнеса, скомпилированные оптимальным образом. Данный методологический подход способствует формированию сбалансированной по составу, объёму и связям модели, отвечающей принципам рациональности. Новая методика экономического обоснования локализации бизнес-систем (объектов промышленного назначения) на орбите разработана в рамках проекта создания космического индустриального ожерелья «Орбита» (КИО «Орбита»).
From Files to Streams: Revisiting Web History and Exploring Potentials for Future Prospects
Creators: name: Vogel, Lucas
name: Springer, Thomas
name: Wählisch, Matthias
Publisher: name: arXiv
Year: 2024
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Over the last 30 years, the World Wide Web has changed significantly. In this paper, we argue that common practices to prepare web pages for delivery conflict with many efforts to present content with minimal latency, one fundamental goal that pushed changes in the WWW. To bolster our arguments, we revisit reasons that led to changes of HTTP and compare them systematically with techniques to prepare web pages. We found that the structure of many web pages leverages features of HTTP/1.1 but hinders the use of recent HTTP features to present content quickly. To improve the situation in the future, we propose fine-grained content segmentation. This would allow to exploit streaming capabilities of recent HTTP versions and to render content as quickly as possible without changing underlying protocols or web browsers.
Метод подбора специалистов, обеспечивающих работоспособность ЭкоКосмоДома на планете Земля
Creators: name: Казначеев Д.В.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: ЭкоКосмоДом на планете Земля (ЭКД-Земля)
замкнутое пространство
исследования
потребности человека
профессиональные навыки
работоспособность

description: Разработан метод подбора специалистов, необходимых для функционирования систем ЭкоКосмоДома на планете Земля (ЭКД-Земля) и обеспечивающих потребности людей, которые проживают в изолированном замкнутом пространстве. Изучен опыт реализации объектов, схожих по условиям эксплуатации («Биосфера-2», «БИОС-3», «Марс-500», Closed Ecological Experimental Facility, «Юэгун-1»), а также по организации территории для проживания и исследований (учебные кампусы) и созданию комфортных условий пребывания человека с целью самосохранения (бомбоубежища). Определена зависимость ключевых параметров, влияющих на ход исследований, – потребностей человека, состава обслуживаемых систем ЭКД-Земля и соответствующих экспериментов, площади и объёма замкнутого пространства.
Free‑floating medial meniscus implant kinematics do not change after simulation of medial open‑wedge high tibial osteotomy and notchplasty
Creators: name: Sukopp, Matthias
name: Shemesh, Maoz
name: Pruech, Elena
name: Linder-Ganz, Eran
name: Hacker, Scott
name: Condello, Vincenzo
name: Schwer, Jonas
name: Ignatius, Anita
name: Dürselen, Lutz
name: Seitz, Andreas Martin
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Implant
subject: DDC 610 / Medicine & health
subject: Arthroplasty, Replacement, Knee
subject: Knee joint
subject: Biomechanical phenomena
subject: Kniegelenkprothese
subject: Biomechanik

description: Purpose The purpose of this in-vitro study was to examine the kinematics of an artificial, free-floating medial meniscus replacement device under dynamic loading situations and different knee joint states. Methods A dynamic knee simulator was used to perform dynamic loading exercises on three neutrally aligned and three 10° valgus aligned (simulating a medial openwedge high tibial osteotomy - MOWHTO) left human cadaveric knee joints. The knee joints were tested in three states (intact, conventional notchplasty, extended notchplasty) while 11 randomised exercises were simulated (jump landing, squatting, tibial rotation and axial ground impacts at 10°, 30° and 60° knee joint flexion) to investigate the knee joint and implant kinematics by means of rigidly attached reflective marker sets and an according motion analysis. Results The maximum implant translation relative to the tibial plateau was < 13 mm and the maximum implant rotation was < 19° for all exercises. Both, the notchplasties and the valgus knee alignment did not affect the device kinematics. Conclusions The results of the present in-vitro study showed that the non-anchored free-floating device remains within the medial knee joint gap under challenging dynamic loading situations without indicating any luxation tendencies. This also provides initial benchtop evidence that the device offers suitable stability and kinematic behaviour to be considered a potential alternative to meniscus allograft transplantation in combination with an MOWHTO, potentially expanding the patient collective in the future.
Bayesian Optimization that Limits Search Region to Lower Dimensions Utilizing Local GPR
Creators: name: Taguchi, Yasunori
name: Gangi, Hiro
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Optimization of product and system characteristics is required in many fields, including design and control. Bayesian optimization (BO) is often used when there are high observing costs, because BO theoretically guarantees an upper bound on regret. However, computational costs increase exponentially with the number of parameters to be optimized, decreasing search efficiency. We propose a BO that limits the search region to lower dimensions and utilizes local Gaussian process regression (LGPR) to scale the BO to higher dimensions. LGPR treats the low-dimensional search region as "local," improving prediction accuracies there. The LGPR model is trained on a local subset of data specific to that region. This improves prediction accuracy and search efficiency and reduces the time complexity of matrix inversion in the Gaussian process regression. In evaluations with 20D Ackley and Rosenbrock functions, search efficiencies are equal to or higher than those of the compared methods, improved by about 69% and 40% from the case without LGPR. We apply our method to an automatic design task for a power semiconductor device. We successfully reduce the specific on-resistance to 25% better than a conventional method and 3.4% better than without LGPR.
description: 8 pages, 13 figures, 22nd International Conference on Machine Learning and Applications (ICMLA2023)
Impact of re-definition of paroxysmal and persistent atrial fibrillation in the 2012 and 2016 European Society of Cardiology atrial fibrillation guidelines on outcomes after pulmonary vein isolation
Creators: name: Weinmann, Karolina
name: Aktolga, Deniz
name: Pott, Alexander
name: Bothner, Carlo
name: Rattka, Manuel
name: Stephan, Tilman
name: Rottbauer, Wolfgang
name: Dahme, Tillman
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Paroxysmal
subject: Persistent
subject: Guidelines
subject: CRYOBALLOON ABLATION
subject: ESC GUIDELINES
subject: FOLLOW-UP
subject: PROGRESSION
subject: DDC 610 / Medicine & health
subject: Atrial fibrillation
subject: Outcome assessment; Health care
subject: Catheter ablation
subject: Vorhofflimmern
subject: Richtlinie
subject: Ablation
subject: Therapieerfolg
subject: Hochfrequenz-Katheterablation
subject: Nachuntersuchung
subject: Management

description: Abstract Purpose In the 2016 European Society of Cardiology (ESC) guidelines for the management of atrial fibrillation (AF), the definition of AF type has been modified compared with the 2010 guidelines and its 2012 focused update. We compared the difference of single procedure outcomes using the definitions before and after 2016 on a cohort of patients with AF undergoing AF ablation. Methods Consecutive AF ablation patients with paroxysmal or persistent AF were retrospectively reclassified applying the 2010, 2012, and 2016 ESC definitions on AF type. Results We included a total of 628 patients. Applying the 2010 ESC AF guidelines definition, 68% of patients were paroxysmal while according to the 2016 ESC AF guidelines, the proportion increased to 87%. Applying the 2010 ESC guidelines definition, recurrence rates of paroxysmal and persistent AF patients differ significantly (log-rank p < 0.001). Applying the 2012 focused update and the 2016 ESC AF guidelines, recurrence rates do not differ significantly. In a cox regression model applying the 2010 guidelines, persistent AF is the only independent predictor of AF recurrence in our cohort. However, when applying the 2016 guidelines, persistent AF is no longer a predictor of AF recurrence. Conclusions The revised definition of AF types in the 2016 ESC AF guidelines leads to a marked shift from persistent to paroxysmal AF. It appears that the old definition provided a better separator to predict rhythm outcome after AF ablation.
title: OFROM: interview avec unine15b04m
Creators: name: Delafontaine, François
name: Rothenbühler, Julie
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.9fdck56q.v2#330255708f181f3a1b9f1abe250c0bb829d70909
Новые формы управления на примере геокосмической платформы Unitsky Space
Creators: name: Юницкий А.Э.
name: Монченко М.С.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: бизнес-модель
платформа
платформа платформ
революция платформ
струнный транспорт
экосистема

description: Раскрываются различия бизнес-моделей и форм управления традиционных линейных и современных платформенных компаний, а также приводится анализ факторов, вызывающих смещение фокуса управления с внутренней активности на внешнюю. Установлено, что геокосмическая платформа Unitsky Space имеет потенциал стать самой масштабной и значимой технологической платформой.
Обоснование экономической и социально-политической эффективности программы SpaceWay для стран-участниц
Creators: name: Юницкий А.Э.
name: Лавриненко В.И.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: динамика
конструкция ОТС
общепланетарное транспортное средство (ОТС)
оптимизация
расчётный случай

description: Рассмотрена оптимальная модель взаимодействия общества и власти в процессе создания общепланетарного транспортного средства (ОТС) на территории стран, расположенных вдоль экватора; представлены возможные результаты этого сотрудничества. Изучены текущая экономическая ситуация и удовлетворённость социально-политических интересов граждан стран-участниц. Установлено, что при реализации инновационного проекта по освоению космоса может быть налажено позитивное взаимодействие власти и общества, выраженное в участии населения в достижении высокого уровня экономического развития и социального прогресса, а также предотвращены глобальные экологические проблемы. Научная новизна исследования состоит в том, что в работе впервые произведена оценка социально-политической эффективности от внедрения программы SpaceWay и показаны экономические выгоды, которые получат участники проекта.
Оптимальная командная матрица для достижения целей конкретного коллектива
Creators: name: Ераховец Н.В.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: замкнутая социальная система
командная матрица
управление персоналом
формирование команды
человеческий капитал

description: Приведён анализ существующих проблем и принципов формирования команд для достижения поставленных целей проекта или компании, оценены современные цифровые технологии в качестве инструментов для усовершенствования механизмов управления персоналом, дано описание методики построения оптимальной командной матрицы для выстраивания конкретного коллектива, в том числе для сложных проектов с замкнутой социальной системой.
RSV vaccination strategies for high-risk patients 2023: a collaborative position paper by leading German medical societies and organizations
Creators: name: Addo, Marylyn
name: Cornely, Oliver
name: Denkinger, Michael
name: Ertl, Georg
name: Herold, Susanne
name: Pletz, Mathias
name: Rohde, Gernot
name: Welte, Tobias
name: Windisch, Wolfram
name: Witzenrath, Martin
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: RSV (respiratory syncytial virus)
subject: Persons aged 60 years or older
subject: Chronic lung disease
subject: Effective vaccines
subject: Severe RSV-associated respiratory infections
subject: Recommendation
subject: DDC 610 / Medicine & health

description: Abstract Respiratory syncytial virus (RSV) inflicts severe illness and courses of infections not only in neonates, infants, and young children, but also causes significant morbidity and mortality in older adults and in people with immunosuppression, hemato-oncologic disease, chronic lung disease, or cardiovascular disease. In June and August 2023, effective vaccines against RSV were approved for the first time by the European Medicines Agency (EMA) for the EU. The respective pivotal studies showed a very high efficacy of the vaccine in preventing severe RSV-associated respiratory infections. At this point, use of the respective vaccines is restricted to persons aged 60 years or older, according to the registration studies. We therefore recommend use of the vaccination in persons aged 60 years or older. In addition, we recommend use of the vaccination in adults of any age with severe pulmonary or cardiovascular pre-existing conditions, as well as in adults with significant immune compromise, after individual consultation with the treating physician. Cost coverage can be applied for individually with the responsible health insurance company. © In Copyright http://rightsstatements.org/vocab/InC/1.0/
Организация внутреннего пространства туристического цилиндрического ЭкоКосмоДома
Creators: name: Юницкий А.Э.
name: Платонова В.А.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: автономная биосфера
космический туризм
пространство
структура
ЭкоКосмоДом (ЭКД)
туристический ЭкоКосмоДом
функциональная зона
экосистема

description: Обозначается актуальность развития космического туризма, рассматриваются существующие предложения и идеи космических туристических баз, разбирается планировочный вариант туристического цилиндрического ЭкоКосмоДома (ЭКД) в рамках программы SpaceWay. В ходе анализа определены основные объёмно-планировочные решения данного объекта, проработаны сценарии расселения, функционирования и обслуживания ЭКД, изучены взаимосвязи объёмов цилиндров и их практическое зонирование.
Организация внутреннего пространства ЭкоКосмоДома на планете Земля
Creators: name: Юницкий А.Э.
name: Ермачёк Е.В.
name: Налётов И.В.
name: Платонова В.А.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: антропогенная среда
изолированная экосистема
объёмно-планировочные решения
проектирование
сельское хозяйство
функциональное зонирование
ЭкоКосмоДом на планете Земля (ЭКД-Земля)
ЭкоКосмоДом (ЭКД)

description: Описаны планировочная схема, объёмное решение, моделирование функциональных связей изолированной замкнутой экосистемы ЭкоКосмоДома на планете Земля (ЭКД-Земля). Основой жизнедеятельности данного комплекса является принцип замкнутого круговорота веществ, энергии и информации. Предлагаемое размещение функциональных зон учитывает важные взаимосвязи устанавливаемых трофических цепей, а также соответствует формируемым абиотическим, климатическим и другим требован иям. Представленный планировочный вариант разработан исходя из ранее определённой конструктивной системы, отвечающей необходимым критериям создания замкнутого пространства ЭКД-Земля. Особенности полученного функционального зонирования – универсальность и трансформируемость к любой форме внутреннего пространства замкнутой экосистемы.
Особая роль пищи как строительного материала для организма человека в условиях замкнутой биосферы ограниченных размеров
Creators: name: Юницкий А.Э.
name: Зыль Н.С.
name: Шахно Е.А.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: биопроизводство
витамины
замкнутая экосистема
макроэлементы
микроэлементы
ультраэлементы
питание
ЭкоКосмоДом (ЭКД)

description: Описаны потребности человека в питательных веществах: ультра-, микро-, макроэлементах, витаминах. Приведены их среднесуточные нормы для мужчин и женщин. Рассмотрены продукты питания как источники восполнения всех жизненно важных веществ в организме человека. Представлены возможные пути их биопроизводства в условиях замкнутой биосферы. Новизна и уникальность исследования состоит в учёте потребности человека в ультра-, микро-, макроэлементах, а также в получении полного набора сельскохозяйственной продукции при использовании минимального объёма замкнутой экосистемы.
Особенности восприятия внутренней архитектурно-пространственной среды ЭкоКосмоДома
Creators: name: Воронович К.П.
name: Кошелев А.Г.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: архитектура
архитектурно-пространственная среда
геопластика
искажённое пространство
ландшафт
рельеф
ЭкоКосмоДом (ЭКД)

description: Изучается восприятие человеком внутренней архитектурно-пространственной среды цилиндрического ЭкоКосмоДома (ЭКД) с учётом своеобразия его формы. Исследуются композиционные особенности пространства для создания условий, удовлетворяющих психологические потребности жителей ЭКД. Дано предложение по решению вопроса искажения восприятия среды, выполнена оценка аналогов и разработаны варианты заполнения территории космического поселения для комфортной жизни человека.
Особенности функционирования маховичного движителя общепланетарного транспортного средства и общие требования к нему
Creators: name: Юницкий А.Э.
name: Бабаян А.В.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: линейный электродвигатель
ленточный маховик
магнитный подвес
общепланетарное транспортное средство (ОТС)
сверхпроводимые магниты
системы охлаждения
энергоэффективность

description: Конструкция привода ленточного маховика общепланетарного транспортного средства (ОТС) во многом схожа с устройством привода электропоезда на магнитной подушке. В обоих случаях используется гибридная система магнитного подвеса и линейного синхронного электродвигателя. Однако в силу целого ряда специфических требований и условий функционирования механизм привода ОТС намного уникальнее. ОТС имеет два независимо движущихся ленточных маховика, поэтому система магнитного подвеса и линейного электродвигателя дублируется. Для космических скоростей движения важно, чтобы ленточные маховики были изолированы в своих вакуумных каналах. Особенно сложным условием является способность корпуса и всех других линейных компонентов конструкции ОТС удлиняться в процессе полёта на 1,57 % каждые 100 км подъёма. Необходим поиск эффективных инженерно-конструкторских решений по бортовым системам энергообеспечения, рекуперации энергии, теплоотвода (охлаждение), а также по достижению электротехническими системами комплексной эффективности на уровне КПД 98–99 %. Кроме того, есть и другие специфические требования к конструкции ОТС, которые тоже разбираются в данной статье.
Müller–Zhang truncation for general linear constraints with first or second order potential
Creators: name: Gallenmüller, Dennis
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Primary 49J45
subject: Secondary 35G05
subject: DDC 510 / Mathematics
subject: Euler, Leonhard, 1707-1783
subject: Eulersche Bewegungsgleichungen

description: Let B be a homogeneous differential operator of order l=1 or l=2. We show that a sequence of functions of the form (Buj)j converging in the L1-sense to a compact, convex set K can be modified into a sequence converging uniformly to this set provided that the derivatives of order l are uniformly bounded. We prove versions of our result on the whole space, an open domain, and for K varying uniformly continuously on an open, bounded domain. This is a conditional generalization of a theorem proved by S. Müller for sequences of gradients. Moreover, a potential of order two for the linearized isentropic Euler system is constructed.
Biosorption of Pb(II) using Gundelia tournefortii: Kinetics, Equilibrium and Thermodynamics
Creators: name: Shojaeimehr, Tahereh
name: Rahimpour, Farshad
name: Sadeghi, Marzieh
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: In this paper, the feasibility of Gundelia tournefortii was studied as a novel, high capacity biosorbent for removing lead ions from synthetic wastewater in batch system. The effect of various parameters such as temperature, initial concentration, initial pH, biosorbent dosage, and contact time were investigated. On the basis of batch results, the optimum operating conditions were found to be pH 5, biosorbent dosage of 25 mg, and temperature of 20 °C in the range of lead initial concentrations from 5 to 100 mg/L. The equilibrium contact time was 60 min. The biosorption mechanism was well described by Langmuir isotherm with a monolayer maximum adsorption capacity of 144.928 (mg/g) at 20 °C and pseudo second order kinetic model. Thermodynamic studies proved that the sorption process was physical, spontaneous, feasible, random, and exothermic. In the second step, the ability of artificial neural network (ANN) for prediction of Gundelia tournefortii adsorption capacity for removal of Pb(II) from aqueous solution was examined. The model was developed using a three-layer feed forward back propagation network with 5, 12 and 1 neurons in the first, second and third layers, respectively. Levenberg–Marquardt back-propagation training algorithm (LMA) was found as the best BP algorithms with a minimum mean squared error of 0.000867 and minimum relative squared error of 0.032771. The comparison between the results of ANN and experimental data showed that ANN has a superior performance (R2= of 0.998) in prediction of Pb(II) removal process.
A medieval seal-matrix from the Cumberland Infirmary, Carlisle.
Creators: name: Cracknell, Philip M
Publisher: name: Archaeology Data Service
Year: 2002

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 99, 278-280
description: Lead `pointed-oval' or almond shaped seal. + S " MATILD " FIL " AL " DE " IRT " or seal of Matilda the daughter of Alan of Irton. Comparable examples (Species I Ringold) date to the early-thirteenth century.
Test DICOM files set for Local control challenge
Creators: name: Fuller, Clifton
name: Mohamed, Abdallah
name: Elhalawani, Hesham
Publisher: name: figshare
Year: 2016
Subjects: subject: 111208 Radiation Therapy
subject: FOS: Clinical medicine

description: This MD Anderson Cancer Center set of anonymized high-quality computed tomography (CT) scans with contrast represent a comparatively homogeneous, uniform cohort of 288 oropharynx cancer patients with detailed clinical history, consistent follow-up of > 2 years, known etiological/biological correlates (specifically, human papilloma virus status). Our major target is to assess/validate the radiomics workflow and predictive capacity of radiomics signatures from challenge participants.We imported the CT scans from the patients’ electronic medical records, that were performed before the initiation of the radiation treatment course. All the patients were treated using the IMRT modality. Some patients were simultaneously prescribed chemotherapy. We intended that the CT films would be as much representative of the original simulation CT scans that were used for treatment planning, in which no contrast was injected according to our institutional policy.Specifically, we posted around one-half of the CT scans from the dataset (138 patients), in DICOM-RT format, on the Kaggle in Class server system, as a “training set”. DICOM-RT files were fully anonymized, with expert physician segmenting primary tumor and lymph node as regions of interest, to eliminate segmentation-related uncertainty for challengers. The primary oropharyngeal tumor was segmented in red. Whereas, the metastatic cervical lymph nodes were segmented individually, rather than on the basis of the nodal level classification system. Both training and test sets include the following data for each DICOM-RT case:agegenderracetumor side and subsiteT-categoryN-categoryAJCC stagePathologic gradesmoking status (in pack-years)Challenge participants will also be able to download a “test" dataset, which includes the remaining randomly selected 150 patients DICOM files and relevant clinical meta-data, with local control status blinded.
The Story of Seathwaite Tarn Reservoir.
Creators: name: Hoyte, Patrick
Publisher: name: Archaeology Data Service
Year: 2002

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 99, 267-276
description: Historical account of the social and economic context in which the damming of Seathwaite Tarn was undertaken during the early-twentieth century. Primarily due to the urban expansion of Barrow-in-Furness, its development through the twentieth century to the present is detailed.
Designing Sousveillance Tools for Gig Workers
Creators: name: Santos, Maya De Los
name: Do, Kimberly
name: Muller, Michael
name: Savage, Saiph
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computers and Society (cs.CY)
subject: Human-Computer Interaction (cs.HC)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: As independently-contracted employees, gig workers disproportionately suffer the consequences of workplace surveillance, which include increased pressures to work, breaches of privacy, and decreased digital autonomy. Despite the negative impacts of workplace surveillance, gig workers lack the tools, strategies, and workplace social support to protect themselves against these harms. Meanwhile, some critical theorists have proposed sousveillance as a potential means of countering such abuses of power, whereby those under surveillance monitor those in positions of authority (e.g., gig workers collect data about requesters/platforms). To understand the benefits of sousveillance systems in the gig economy, we conducted semi-structured interviews and led co-design activities with gig workers. We use "care ethics" as a guiding concept to understand our interview and co-design data, while also focusing on empathic sousveillance technology design recommendations. Through our study, we identify gig workers' attitudes towards and past experiences with sousveillance. We also uncover the type of sousveillance technologies imagined by workers, provide design recommendations, and finish by discussing how to create empowering, empathic spaces on gig platforms.
description: Published as a conference paper at the ACM Conference on Human Factors in Computing Systems, CHI 2024, 3 figures, 30 pages
Intoxication of mammalian cells with binary clostridial enterotoxins is inhibited by the combination of pharmacological chaperone inhibitors
Creators: name: Ernst, Katharina
name: Sailer, Judith
name: Braune, Maria
name: Barth, Holger
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Bacterial protein toxins
subject: Pharmacological inhibitors
subject: Chaperones
subject: Cellular uptake
subject: Clostridioides difficile
subject: CDT toxin
subject: BOTULINUM C2 TOXIN
subject: ADP-RIBOSYLATING TOXINS
subject: PERFRINGENS IOTA-TOXIN
subject: MEMBRANE TRANSLOCATION
subject: DIPHTHERIA-TOXIN
subject: C-2 TOXIN
subject: ACTIN
subject: HSP90
subject: DIFFICILE
subject: DDC 610 / Medicine & health

description: Abstract Binary enterotoxins Clostridioides difficile CDT toxin, Clostridium botulinum C2 toxin, and Clostridium perfringens iota toxin consist of two separate protein components. The B-components facilitate receptor-mediated uptake into mammalian cells and form pores into endosomal membranes through which the enzymatic active A-components translocate into the cytosol. Here, the A-components ADP-ribosylate G-actin which leads to F-actin depolymerization followed by rounding of cells which causes clinical symptoms. The protein folding helper enzymes Hsp90, Hsp70, and peptidyl-prolyl cis/trans isomerases of the cyclophilin (Cyp) and FK506 binding protein (FKBP) families are required for translocation of A-components of CDT, C2, and iota toxins from endosomes to the cytosol. Here, we demonstrated that simultaneous inhibition of these folding helpers by specific pharmacological inhibitors protects mammalian, including human, cells from intoxication with CDT, C2, and iota toxins, and that the inhibitor combination displayed an enhanced effect compared to application of the individual inhibitors. Moreover, combination of inhibitors allowed a concentration reduction of the individual compounds as well as decreasing of the incubation time with inhibitors to achieve a protective effect. These results potentially have implications for possible future therapeutic applications to relieve clinical symptoms caused by bacterial toxins that depend on Hsp90, Hsp70, Cyps, and FKBPs for their membrane translocation into the cytosol of target cells.
Potential sex differences in human milk fatty acids and their association with atopic dermatitis: Results of the Ulm SPATZ health study
Creators: name: Ordnung, Madeleine
name: Mank, Marko
name: Stahl, Bernd
name: Kurz, Deborah
name: Marosvölgyi, Tamas
name: Decsi, Tamas
name: Rothenbacher, Dietrich
name: Genuneit, Jon
name: Siziba, Linda P.
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: atopic dermatitis
subject: human milk
subject: infant sex
subject: polyunsaturated fatty acids
subject: UMBILICAL-CORD
subject: BREAST-MILK
subject: ECZEMA
subject: DDC 610 / Medicine & health

description: Abstract Background Polyunsaturated fatty acids (PUFAs) in human milk are essential in immune system maturation and might play a role in the development of allergic conditions, such as atopic dermatitis (AD) in infants. Immune system responses are modulated by sex, but data on the sex‐specific associations with PUFAs are limited. We therefore explored sex‐specific differences in human milk PUFAs and their association with AD up to 2 years. Methods PUFAs were measured in human milk samples from the Ulm SPATZ Health Study at 6 weeks (n = 512) and 6 months (n = 367). Associations with AD up to 2 years were evaluated using crude and multivariable logistic regression. Interactions between infant sex and PUFAs were explored by including the product term. Results No significant associations were observed with 6‐week data. At 6 months, the median relative proportion of docosahexaenoic acid (DHA) was significantly higher in milk for female than male infants (p = .001). Female infants whose milk was lower in quintile proportions of alpha‐linolenic acid (ALA) at 6 months had lower odds of AD compared to males [first vs. fifth quintile OR (95% confidence interval): 0.13 (0.02, 0.66), p = .02]. This interaction was not significant when correcting for multiple testing (α threshold: p = .004). No other statistically significant associations were observed. Conclusion Individual quintile PUFA proportions in human milk were not associated with AD, overall and in a sex‐specific manner. More comprehensive and statistically powered longitudinal studies are needed to determine whether potential sex differences in human milk, if any, could be of clinical relevance for infants including the investigation of mediating factors.
title: 02_0937
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Очистка озёрной воды с помощью минеральной загрузки
Creators: name: Налётов И.В.
name: Заяц В.С.
name: Боричевский А.Н.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: водообмен
минеральная загрузка
очистка воды
параметры очистки
фильтрация воды
ЭкоКосмоДом (ЭКД)
ЭкоКосмоДом на планете Земля (ЭКД-Земля)
экологичность

description: Водные экосистемы обладают способностью к самоочищению и постепенному приходу к биологическому равновесию, которое в свою очередь достигается действием различных физических, химических и биологических факторов. Очистка воды в рамках изолированной закрытой экосистемы является одной из первостепенных и важных задач. Основу для решения данной проблемы составляет подбор соответствующей минеральной загрузки.
Pyrolysis of commingled waste textile fibers in a batch reactor: Analysis of the pyrolysis gases and solid product
Creators: name: Cigdem Balcik-Canbolat
name: Ozbey, Bahar
name: Dizge, Nadir
name: Bulent Keskinler
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry

description: The main object of this study was the investigation of the thermal recycling of commingled waste textile fibers, with the aim of the production of useful end products. Differential scanning calorimetry/Thermo gravimetric analysis (DSC/TGA) was applied to determine the thermal degradation characteristics of the commingled waste textile fibers and there are two peaks located at the temperature ranges of 299–360°C and 399–500°C. Commingled waste fiber was pyrolyzed in a nitrogen atmosphere in relation to three different temperatures (500, 600, and 700°C), heating rates (25 and 50°C min−1), and retention times (15 and 30 min). The effect of the experimental conditions such as pyrolysis temperature, heating rates, and retention time on the formation of char and gas--liquid products was investigated and the product yields were determined from the rate of the weight loss. The highest conversion rate 82.9 wt.% liquid--gas product and 17.1 wt.% char product was achieved at 700°C. Pyrolysis gases were taken for every 7, 15, and 25 min and were analyzed for major components such as CO, CO2, CH4, and H2 by gas chromatography. The pyrolysis char called as carbon black derived from the pyrolysis of commingled waste textile fibers was analyzed for a range of properties, including the elemental analysis, moisture content, ash content, calorific value, and trace metal analysis.
Redox‐mediated red‐phosphorous semi‐liquid anode enabling metal‐free rechargeable na‐seawater batteries with high energy density
Creators: name: Kim, Yongil
name: Varzi, Alberto
name: Mariani, Alessandro
name: Kim, Guk‐Tae
name: Kim, Youngsik
name: Passerini, Stefano
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: redox mediators
subject: seawater batteries
subject: semi‐liquid anodes
subject: DDC 540 / Chemistry & allied sciences
subject: Phosphorus
subject: Polycyclic aromatic hydrocarbons
subject: Oxidation-reduction reaction
subject: Sodium
subject: Phosphor
subject: Natrium

description: Red‐phosphorus semi‐liquid electrodes are investigated as anodes for metal‐free rechargeable Na‐seawater batteries with high energy density. The red‐phosphors semi‐liquid electrode, made by mixing P/C composite powder with a redox‐mediators‐based electrolyte solution (P/C @ Na‐BP‐PYRs), enables a high areal capacity of 26 mAh using a small coin cell. The two redox mediators act as reducing and oxidizing species for the red‐phosphorus. Sodium‐seawater batteries (Na‐SWB) are considered among the most promising electrochemical devices for large‐scale energy storage and the marine sector. In fact, by employing an open‐structured cathode, they benefit from the unlimited supply of sodium from seawater. This means, that the energy of such systems is intrinsically limited by the capacity of the anode. In order to increase the energy of Na‐SWB, it is therefore necessary to introduce a high‐capacity anode such as, e.g., red phosphorus. However, due to its large volume changes upon charge/discharge processes, obtaining thick electrodes and large areal capacity is extremely challenging. Herein, the areal/absolute capacity of the red phosphorus anode is increased by employing a semi‐liquid electrode, which includes two redox mediators, i.e., sodium‐biphenyl and sodium‐pyrene, as reducing and oxidizing species for the exploitation of the full red phosphorus capacity. As a result, the red phosphorus semi‐liquid anode in Na‐SWB provides a high‐capacity of 15 mAh cm–2 in a static anode, showing great energy storage potential for operation in flow‐mode when storing the semi‐liquid negative electrode in a storage tank.
Expression profiles of the autism-related SHANK proteins in the human brain
Creators: name: Wölfle, Sarah
name: Pedro, Maria T.
name: Wagner, Jan
name: Schön, Michael
name: Böckers, Tobias M.
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: SHANK2
subject: SHANK3
subject: Post mortem human brain
subject: Brain regions
subject: Protein expression
subject: Autism spectrum disorders
subject: DDC 610 / Medicine & health
subject: Protein folding
subject: Autismus

description: Background SHANKs are major scaffolding proteins at postsynaptic densities (PSDs) in the central nervous system. Mutations in all three family members have been associated with neurodevelopmental disorders such as autism spectrum disorders (ASDs). Despite the pathophysiological importance of SHANK2 and SHANK3 mutations in humans, research on the expression of these proteins is mostly based on rodent model organisms. Results In the present study, cellular and neuropil SHANK2 expression was analyzed by immunofluorescence (IF) staining of post mortem human brain tissue from four male individuals (19 brain regions). Mouse brains were analyzed in comparison to evaluate the degree of phylogenetic conservation. Furthermore, SHANK2 and SHANK3 isoform patterns were compared in human and mouse brain lysates. While isoform expression and subcellular distribution were largely conserved, differences in neuropil levels of SHANK2 were found by IF staining: Maximum expression was concordantly measured in the cerebellum; however, higher SHANK2 expression was detected in the human brainstem and thalamus when compared to mice. One of the lowest SHANK2 levels was found in the human amygdala, a moderately expressing region in mouse. Quantification of SHANK3 IF in mouse brains unveiled a distribution comparable to humans. Conclusions In summary, these data show that the overall expression pattern of SHANK is largely conserved in defined brain regions; however, differences do exist, which need to be considered in the translation of rodent studies. The summarized expression patterns of SHANK2 and SHANK3 should serve as a reference for future studies.
Потенциал использования целлюлозолитических микроорганизмов для биодеградации твёрдых бытовых отходов
Creators: name: Юницкий А.Э.
name: Соловьёва Е.А.
name: Парфенчик М.М.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: биоразложение отходов
загрязнение окружающей среды
микроорганизмы-деструкторы

description: Одна из первоочередных задач современного общества – сбор и утилизация отходов, поскольку их объём с каждым годом увеличивается. Небрежное обращение с ними приводит к загрязнению окружающей среды и негативно сказывается на здоровье человека. Традиционные способы обезвреживания твёрдых отходов, такие как захоронение или сжигание, не могут справиться с существующей проблемой, поэтому необходимо искать новые пути её решения. Использование экологически безопасного биологического разложения загрязнителей живыми организмами (бактериями, грибами, водорослями и др.) с возможностью получения ценных промышленных продуктов (биоудобрения, биогаза и др.) является актуальным и перспективным направлением биотехнологии. В рамках эксперимента авторами отобрана ассоциация целлюлозолитических микроорганизмов (№ 3), обладающая широким спектром деструктивной активности и большим потенциалом для биотрансформации твёрдых бытовых отходов в продукты с хозяйственно-ценными свойствами.