cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Arterial function in response to a 50 km ultramarathon in recreational athletes
Creators: name: Ranadive, Sushant M.
name: Weiner, Cynthia M.
name: Eagan, Lauren E.
name: Addison, Odessa
name: Landers-Ramos, Rian Q.
name: Prior, Steven J.
Publisher: name: Wiley
Year: 2024

description: This study was performed to determine whether prolonged endurance running results in acute endothelial dysfunction and wave-reflection, as endothelial dysfunction and arterial stiffness are cardiovascular risk factors. Vascular function (conduit artery/macrovascular and resistance artery/microvascular) was assessed in 11 experienced runners (8 males, 3 females) before, during and after a 50 km ultramarathon. Blood pressure (BP), heart rate (HR), wave reflection, augmentation index (AIx) and AIx corrected for HR (AIx75) were taken at all time points—Baseline (BL), following 10, 20, 30 and 40 km, 1 h post-completion (1HP) and 24 h post-completion (24HP). Flow-mediated dilatation (FMD) and inflammatory biomarkers were examined at BL, 1HP and 24HP. Reactive hyperaemia area under the curve (AUC) and shear rate AUC to peak dilatation were lower (∼75%) at 1HP compared with BL (P < 0.001 for both) and reactive hyperaemia was higher at 24HP (∼27%) compared with BL (P = 0.018). Compared to BL, both mean central systolic BP and mean central diastolic BP were 7% and 10% higher, respectively, following 10 km and 6% and 9% higher, respectively, following 20 km, and then decreased by 5% and 8%, respectively, at 24HP (P < 0.05 for all). AIx (%) decreased following 20 km and following 40 km compared with BL (P < 0.05 for both) but increased following 40 km when corrected for HR (AIx75) compared with BL (P = 0.02). Forward wave amplitude significantly increased at 10 km (15%) compared with BL (P = 0.049), whereas backward wave reflection and reflected magnitude were similar at all time points. FMD and baseline diameter remained similar. These data indicate preservation of macrovascular (endothelial) function, but not microvascular function resulting from the 50 km ultramarathon.
Additional file 1: of An analysis of global youth tobacco survey for developing a comprehensive national smoking policy in Timor-Leste
Creators: name: Sarmento, Decio Ribeiro
name: Degninou Yehadji
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: STROBE Statementâ  Checklist of items that should be included in reports of cross-sectional studies. (PDF 127 kb)
MOESM4 of Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model
Creators: name: Paktiya Teja-Isavadharm
name: Duangsuda Siriyanonda
name: Maneerat Rasameesoraj
name: Amporn Limsalakpeth
name: Nitima Chanarat
name: Natthasorn Komcharoen
name: Weina, Peter
name: Saunders, David
name: Montip Gettayacamin
name: R. Scott Miller
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 4. Parasite-time profiles and recrudescence (R) day following once daily dose of IV AL 11.8, 5.6, 5.6 mg kg−1 and IV AS 8.0, 4, 4 mg kg−1 for 3 days, showing mean and 95 % confidence in plasma of P. coatneyi infected rhesus monkeys including quinine control for each treatment and percentage (mean and 95 %CI) of parasite reduction after treatment.
Neomedaura arguta Xie & Wen & Chen & Wang & Qian 2023, comb. nov.
Creators: name: Xie, Chong-Xin
name: Wen, Jun
name: Chen, Wang
name: Wang, Zhao-Zi
name: Qian, Yu-Han
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Phasmida
Phasmatidae
Neomedaura
Neomedaura arguta

description: Neomedaura arguta (Chen & He, 2008) comb. nov.
Fig. 4
Pachymorpha arguta Chen & He, 2008: 206, fig. 171 a–c, 417. ♀ HT, China, Yunnan Province, Xishuanganna, Damenglong 650 m, 16.VII.1958, leg. Zhang Yi-Ran (IZCAS).
Remarks: Female (only sex known) medium-sized (body length 74 mm); unarmed, slender and long, only with a few small granules; with distinct needle-shaped preopercular organ on posteromedian area of seventh sternum; anal segment with a small emargination on posterior margin; all legs smooth and without serrations as far as known (forelegs are missing). Based on the adult morphology, Pachymorpha arguta belongs to the genus Neomedaura, rather than in Pachymorpha and the species is here transferred to Neomedaura in a new combination.
Similar species: The species is closely related to N.yokdonensis Ho, 2020, but can be distinguished by the female of with distinct needle-shaped preopercular organ on posteromedian area of seventh sternum. In N. yokdonensis the female has a distinct horn-like preopercular organ on posteromedian area of seventh sternum.
Chinese common name. ṪDḿDz(mffi)
description: Published as part of Xie, Chong-Xin, Wen, Jun, Chen, Wang, Wang, Zhao-Zi & Qian, Yu-Han, 2023, Two new combinations of Medaurini (Phasmatodea: Phasmatidae: Clitumninae) from Yunnan Province, China, pp. 567-576 in Zootaxa 5323 (4) on page 573, DOI: 10.11646/zootaxa.5323.4.7, http://zenodo.org/record/8225227
MOESM3 of Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model
Creators: name: Paktiya Teja-Isavadharm
name: Duangsuda Siriyanonda
name: Maneerat Rasameesoraj
name: Amporn Limsalakpeth
name: Nitima Chanarat
name: Natthasorn Komcharoen
name: Weina, Peter
name: Saunders, David
name: Montip Gettayacamin
name: R. Scott Miller
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 3. The antimalarial effect-time profiles as measured by bioassay following intravenous artelinate (lysine salt) 11.8 mg/kg and artesunate (sodium salt) 8.0 mg/kg in healthy and P. coatneyi infected rhesus monkeys. Values are mean and 95 % confidence interval of antimalarial activity expressed as DHA equi. in μmole L−1.
An ectomycorrhizal symbiosis? a morphological and molecular characterization of Tricholoma magnivelare in Pinus contorta roots from the West Chilcotin Plateau of British Columbia, Canada
Creators: name: Bravi, Rebecca Sue
Publisher: name: University of British Columbia
Year: 2009

description: The utility of the T. magnivelare/P. contorta ectomycorrhizal classification is evaluated using a strictly anatomical definition of the symbiosis proposed by Jones & Smith (2004) in which the presence of structural features Hartig net, mantle and extramatrical hyphae characterize the mycorrhizal state. A combined molecular and morphological approach was adopted to analyse samples of P. contorta roots collected from beneath T. magnivelare sporocarps from pine stands in four ecosystems in the West Chilcotin Plateau of British Columbia, Canada. Roots mass samples were assessed and four root morphotypes were described; matchstick root, blackened root, fleshy root and cottony root. Two primer sets were developed to amplify the ITS region of the ribosomal DNA in T. magnivelare. Primer set one amplifies all commercially significant T. magnivelare, from across North America including some T. caligatum. Primer set two specifically amplifies T. magnivelare from the Pacific Northwest of the United States and Canada. Primers testing against a suite of 33 other Tricholoma species and 12 other genera demonstrated the primers performed well. Primer set one initially showed strong and specific amplification of the target species but later in the test an apparent contamination problem developed, further testing is recommended to verify this. Primer set two demonstrated a high specificity to T. magnivelare from the Pacific Northwest of the US and Canada and was used to confirm the presence of T. magnivelare in 10 samples each of the root morphologies. In all samples T. magnivelare presence was established. Root morphotypes and root masses were assessed for the presence of the defining structural features of ectomycorrhizae. These features were not consistently observed individually or in combination. A variety of mantle-like structures were observed and all features were observed in association with necrotizing root tissue. It is therefore the concluded that the current classification of the T. magnivelare/P. contorta symbiosis as ectomycorrhizal is not concordant with the definition of the symbiosis adopted for this study nor would it encourage a full appreciation of the complexity of this symbiotic relationship.
Additional file 2 of Costing curative outpatient care for the poorest in Burkina Faso: informing universal health coverage and leaving no one behind
Creators: name: Beaugé, Yvonne
name: Ridde, Valéry
name: Souleymane, Sidibé
name: Kiendrébéogo, Joël Arthur
name: Nguyen, Hoa Thi
name: Bonnet, Emmanuel
name: De Allegri, Manuela
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2.
Additional file 1: of Heritable gene expression differences between apomictic clone members in Taraxacum officinale: Insights into early stages of evolutionary divergence in asexual plants
Creators: name: Carvalho, Julie Ferreira De
name: Oplaat, Carla
name: Pappas, Nikolaos
name: Derks, Martijn
name: Ridder, Dick De
name: Verhoeven, Koen
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Presentation of the five accessions, microsatellite data for eight markers and sampling sites. (DOCX 15Â kb)
Scytocera Redtenbacher 1891
Creators: name: Rentz, D. C. F.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Scytocera

description: Scytocera Redtenbacher, 1891
Scytocera prasinus Karny 1921 was described from the Endeavour River, Queensland, Australia in Dicranocercus Redtenbacher 1891, the type species of which is D. niger Redtenbacher 1891 by original monotypy. D. prasinus is misplaced in Scytocera which includes very dissimilar species, none of which occur in or near Australia. There is no described genus which could accommodate D. prasinus and I propose Goodangarkia Rentz gen. nov., derived from an aboriginal word for Cape York, feminine gender. The type species is here designated as Dicranocercus prasinus Redtenbacher 1891. This genus comprises two known species, both from the northern portion of the Cape York Peninsula, Queensland and adjacent islands. Both are richly green with highly distinctive markings. S. prasinus is fully winged with the tegmina and wings slightly surpassing the apex of the abdomen. The second species is brachypterous, with the male tegmina only slightly longer than the length of the pronotum. This species will be described at a later date. Male and female genitalia and titillators are species distinctive. The ovipositor is sickle-shaped and shorter than the length of the hind femur but longer than the length of the pronotum.
description: Published as part of Rentz, D. C. F., 2009, Nomenclatural Changes in Australian Tettigoniidae, pp. 67-68 in Zootaxa 2221 (1) on page 67, DOI: 10.11646/zootaxa.2221.1.5, http://zenodo.org/record/5319414
Additional file 1: of Cynicism and other attitudes towards patients in an emergency department in a middle eastern tertiary care center
Creators: name: Batley, Nicholas
name: Nasreddine, Zeina
name: Chami, Ali
name: Zebian, Dina
name: Bachir, Rana
name: Abbas, Hussein
Publisher: name: Figshare
Year: 2016
Subjects: Medicine
Cancer
Science Policy

description: List of the semi-structurered interview questions. (DOC 32Â kb)
Bildklassifizierung mit Neuronalen Netzen
Creators: name: Ebert, David
Publisher: name: Hochschulbibliothek, Hochschule Merseburg
Year: 2019
Subjects: subject: Neuronale Netze
subject: Visual Studio Code
subject: TensorFlow
subject: Keras
subject: Bildverarbeitung
subject: DDC::000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::004 Datenverarbeitung; Informatik

description: Auf den folgenden Seiten dieser Abschlussarbeit werden grundlegende Einblicke in die Entwicklung eines Neuronalen Netzes vermittelt. Dabei wird auf das besondere Umfeld sowie ausgewählte Eigenheiten eingegangen und ein Überblick über die verwendete Entwicklungsumgebung verschafft. Der Fokus der Arbeit liegt auf den entsprechenden Möglichkeiten unter Verwendung von Visual Studio Code, TensorFlow und Keras. Außerdem wird in dieser Abschlussarbeit untersucht, ob Unterschiede in der Größe der Bilder einen Einfluss auf die Genauigkeit und die Performance des zu entwickelnden Neuronalen Netzes aufweisen. Auch wird untersucht ob verschiedene Aktivierungsfunktionen und Optimizer die Genauigkeiten des Netzwerkes beeinflussen können.
Additional file 3 of Costing curative outpatient care for the poorest in Burkina Faso: informing universal health coverage and leaving no one behind
Creators: name: Beaugé, Yvonne
name: Ridde, Valéry
name: Souleymane, Sidibé
name: Kiendrébéogo, Joël Arthur
name: Nguyen, Hoa Thi
name: Bonnet, Emmanuel
name: De Allegri, Manuela
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 3.
MOESM6 of Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model
Creators: name: Paktiya Teja-Isavadharm
name: Duangsuda Siriyanonda
name: Maneerat Rasameesoraj
name: Amporn Limsalakpeth
name: Nitima Chanarat
name: Natthasorn Komcharoen
name: Weina, Peter
name: Saunders, David
name: Montip Gettayacamin
name: R. Scott Miller
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 6. Pharmacokinetic parameters of parent drug (AS) and metabolite (DHA) and effect kinetic parameters following I.V. AS/Na 8Â mg/kg, in healthy and P. coatneyi infected rhesus monkeys with their means, 95Â % confidence intervals, and coefficient of variation (%CV) values.
Measuring Union Formalization for a New Generation of Family Demography: A Case Study from Urban Kenya
Creators: name: Stoebenau, Kirsten
name: Madhavan, Sangeetha
name: Kim, Seungwan
name: Wainaina, Carol
Publisher: name: Wiley
Year: 2024

description: Despite repeated calls for improved measures of marriage as a process in sub-Saharan Africa, large-scale surveys continue to rely on static marital status. As a result, there is an incomplete understanding of the effects of marriage on outcomes of interest. We use qualitative and survey data from a longitudinal study of 1,203 young mothers residing in informal settlements of Nairobi, Kenya, to (1) describe the development of an innovative measure of union formalization (UF) defined as the steps through which a union attains social legitimacy; (2) compare UF with a conventional current marital status measure; (3) examine the distribution of UF steps across union history; and (4) examine the sequence and timing of pregnancy and childbearing within the UF process. We find UF steps indicative of both increasing individualization of marriage and the ongoing importance of kin involvement hold meaning. We demonstrate extensive heterogeneity in the sequence and extent of UF steps completed and interrogate the classification of premarital childbearing using sequence analysis. We argue that measuring UF is feasible and necessary for the next generation of family demography in Africa; UF measures facilitate understanding the linkages among family dynamics, health, and social stratification within the context of ongoing socioeconomic change.
Reviving anthropology's past: Digital archival access and ethical collaboration with Indigenous communities
Creators: name: Sorensen, Amanda H.
name: Lee, Samantha
name: Marsh, Diana E.
name: Fenlon, Katrina
name: Punzalan, Ricardo L.
Publisher: name: Wiley
Year: 2023

description: This article outlines the revitalization of the Council for the Preservation of Anthropological Records (CoPAR) to adapt to the changing dynamics of archival data reuse in anthropology. It begins by examining the prevailing discourse on anthropological data, archives and their reuse, then explores interdisciplinary data curation trends. Recent initiatives include collaborations with Wikipedia and Wikidata and innovative design strategies to improve access to anthropological archives. The article also discusses the ethical and logistical challenges faced during this transformation. The overarching vision presented is to position CoPAR as a central hub that connects archivists, anthropologists and Indigenous communities, ensuring streamlined and ethical access to anthropological records in the digital realm.
Additional file 1: Table S1. of Retreatment with anti-EGFR based therapies in metastatic colorectal cancer: impact of intervening time interval and prior anti-EGFR response
Creators: name: X. Liu
name: G. George
name: A. Tsimberidou
name: A. Naing
name: J. Wheler
name: S. Kopetz
name: S. Fu
name: S. Piha-Paul
name: C. Eng
name: G. Falchook
name: F. Janku
name: C. Garrett
name: D. Karp
name: R. Kurzrock
name: R. Zinner
name: K. Raghav
name: V. Subbiah
name: K. Hess
name: F. Meric-Bernstam
name: D. Hong
name: M. Overman
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Combined effect of prior response and long interval upon clinical benefit on anti-EGFR clinical trial retreatment. (DOC 30Â kb)
Additional file 4 of Costing curative outpatient care for the poorest in Burkina Faso: informing universal health coverage and leaving no one behind
Creators: name: Beaugé, Yvonne
name: Ridde, Valéry
name: Souleymane, Sidibé
name: Kiendrébéogo, Joël Arthur
name: Nguyen, Hoa Thi
name: Bonnet, Emmanuel
name: De Allegri, Manuela
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 4.
Electrical Resistivity as an Alternative to the Atterberg Test
Creators: name: Noonan, Matthew
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 40
subject: Engineering
classificationCode: 4005
subject: Civil engineering
subject: FOS: Civil engineering
classificationCode: 400502
subject: Civil geotechnical engineering

description: A thesis submitted in total fulfilment of the requirements for the degree of Master of Engineering to the School of Computing, Engineering and Mathematical Sciences, La Trobe University, Victoria, Australia.
Spintronic Quantum Phase Transition in aGraphene/Pb0.24 Sn 0.76 Te Heterostructure with Giant RashbaSpin-Orbit Coupling
Creators: name: DeMell, Jennifer E.
name: Naumov, Ivan
name: Stephen, Gregory M.
name: Blumenschein, Nicholas A.
name: Leo Sun, Y.-J.
name: Fedorko, Adrian
name: Robinson, Jeremy T.
name: Campbell, Paul M.
name: Taylor, Patrick J.
name: Heiman, Don
name: Dev, Pratibha
name: Hanbicki, Aubrey T.
name: Friedman, Adam L.
Publisher: name: Wiley
Year: 2023

description: Mechanical stacking of two dissimilar materials often has surprising consequences for heterostructure behavior. In particular, a 2D electron gas (2DEG) is formed in the heterostructure of the topological crystalline insulator Pb0.24Sn0.76Te and graphene due to contact of a polar with a nonpolar surface and the resulting changes in electronic structure needed to avoid polar catastrophe. The spintronic properties of this heterostructure with non-local spin valve devices are studied. This study observes spin-momentum locking at lower temperatures that transitions to regular spin channel transport only at ≈40 K. Hanle spin precession measurements show a spin relaxation time as high as 2.18 ns. Density functional theory calculations confirm that the spin-momentum locking is due to a giant Rashba effect in the material and that the phase transition is a Lifshitz transition. The theoretically predicted Lifshitz transition is further evident in the phase transition-like behavior in the Landé g-factor and spin relaxation time.
On the Role of Indian Ocean SST in Influencing the Differences in Atmospheric Variability Between 2020–2021 and 2021–2022 La Niña Boreal Winters
Creators: name: Zhang, Tao
name: Kumar, Arun
Publisher: name: Wiley
Year: 2024

description: The difference in observed atmospheric anomalies over the Northern Hemisphere winter between 2021–22 and 2020–21 La Niña years indicated a tripole pattern consisting of a Japan cyclone, a Bering Sea anticyclone, and a cyclone over the North American continent. This feature, however, was not replicated in the North American Multi-Model Ensemble (NMME) forecasts. A set of model sensitivity experiments was performed to better understand the cause of this discrepancy. The results revealed the possible role of the influence of sea surface temperature (SST) anomalies, particularly over the Indian Ocean, on the observed circulation differences that was further modulated by internal atmospheric variability. The failure in predicting circulation changes in NMME was next attributed to the errors in SST predictions over the Indian Ocean and highlights the need for improvements in SST forecasts over this region.
Nicsara Walker 1869
Creators: name: Rentz, D. C. F.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Nicsara

description: Nicsara Walker
Nicsara falcata Redtenbacher 1891 is formally transferred from Nicsara Walker 1869 to Austrosalomona Rentz 1988. This was suggested by Rentz (1988) for it and a number of other species and the combination was used in Rentz (1996) but the formal transfer has never been made or justified until now. The type series of N. falcata, now Austrosalomona falcata (Redtenbacher), is in the Naturhistoriches Museum, Wien. The lectotype (Fig. 1) is here designated with the type locality of the specimen labelled “Northern Australia ”. This is a common species along the coast from Bateman’s Bay, New South Wales north to the vicinity of Cairns, Queensland.
description: Published as part of Rentz, D. C. F., 2009, Nomenclatural Changes in Australian Tettigoniidae, pp. 67-68 in Zootaxa 2221 (1) on page 68, DOI: 10.11646/zootaxa.2221.1.5, http://zenodo.org/record/5319414
Haanina patinifera
Creators: name: Gupta, Sunil Kumar
name: Chandra, Kailash
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Blattodea
Blaberidae
Haanina
Haanina patinifera

description: 52. Haanina patinifera (Bolívar, 1897)
Homalopteryx patinifera Bolívar, 1897: 295.
References. Princis, 1967: 644; Mukherjee & Hazra, 1991: 264.
Distribution. India: Kerala, Lakshadweep Island and Tamil Nadu.
Depository. Not recorded.
description: Published as part of Gupta, Sunil Kumar & Chandra, Kailash, 2019, An annotated checklist of cockroaches (Blattodea) from India, pp. 461-497 in Zootaxa 4614 (3) on page 471, DOI: 10.11646/zootaxa.4614.3.3, http://zenodo.org/record/3243068
Characterisation of sRNAs enriched in outer membrane vesicles of pathogenic Flavobacterium psychrophilum causing Bacterial Cold Water Disease in rainbow trout
Creators: name: Chapagain, Pratima
name: Ali, Ali
name: Kidane, Destaalem T.
name: Farone, Mary
name: Salem, Mohamed
Publisher: name: Wiley
Year: 2024

description: Flavobacterium psychrophilum (Fp) causes Bacterial Cold Water Disease in salmonids. During host-pathogen interactions, gram-negative bacteria, such as Fp, release external membrane vesicles (OMVs) harbouring cargos, such as DNA, RNA and virulence factors. This study aimed to characterise the potential role of the OMVs’ small RNAs (sRNAs) in the Fp-rainbow trout host-pathogen interactions. sRNAs carried within OMVs were isolated from Fp. RNA-Seq datasets from whole-cell Fp and their isolated OMVs indicated substantial enrichment of specific sRNAs in the OMVs compared to the parent cell. Many of the OMV-packaged sRNAs were located in the pathogenicity islands of Fp. Conservation of sRNAs in 65 strains with variable degrees of virulence was reported. Dual RNA-Seq of host and pathogen transcriptomes on day 5 post-infection of Fp -resistant and -susceptible rainbow trout genetic lines revealed correlated expression of OMV-packaged sRNAs and their predicted host's immune gene targets. In vitro, treatment of the rainbow trout epithelial cell line RTgill-W1 with OMVs showed signs of cytotoxicity accompanied by dynamic changes in the expression of host genes when profiled 24 h following treatment. The OMV-treated cells, similar to the Fp -resistant fish, showed downregulated expression of the suppressor of cytokine signalling 1 (SOCS1) gene, suggesting induction of phagosomal maturation. Other signs of modulating the host gene expression following OMV-treatment include favouring elements from the phagocytic, endocytic and antigen presentation pathways in addition to HSP70, HSP90 and cochaperone proteins, which provide evidence for a potential role of OMVs in boosting the host immune response. In conclusion, the study identified novel microbial targets and inherent characteristics of OMVs that could open up new avenues of treatment and prevention of fish infections.
Additional file 1 of Treelink: data integration, clustering and visualization of phylogenetic trees
Creators: name: Allende, Christian
name: Sohn, Erik
name: Little, Cedric
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: Plant Biology

description: Clustering Algorithm. The clustering algorithm, along with the mathematical explanation based on graph theory. Pseudo-Code included. (PDF 169 kb)
Additional file 1: of Treatment with l-citrulline and metformin in Duchenne muscular dystrophy: study protocol for a single-centre, randomised, placebo-controlled trial
Creators: name: Hafner, Patricia
name: Bonati, Ulrike
name: Rubino, Daniela
name: Gocheva, Vanya
name: Zumbrunn, Thomas
name: Gueven, Nuri
name: Fischer, Dirk
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: SPIRIT checklist. (PDF 60.4 kb)
Additional file 1: of Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice
Creators: name: Suzuki, Akari
name: Kochi, Yuta
name: Shoda, Hirofumi
name: Seri, Yu
name: Fujio, Keishi
name: Sawada, Tetsuji
name: Yamada, Ryo
name: Yamamoto, Kazuhiko
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Marine Biology
subject: 60506 Virology
subject: Computational Biology

description: Generation of a Padi4−/− mouse. (a) Genomic structure of A Padi4−/− mouse. A 5837-bp fragment containing exon 1 and intron 1 of Padi4 was inserted to the targeting vector. We constructed the targeting vector to replace exon 1 and intron 1, including the transcription initiation site, using mouse PGK-1 promoter and the neomycin-resistance gene. We confirmed the knockout condition by Southern blotting (b) and RT-PCR (c). (d) Distributions of immune cells in the spleen of wild-type (n = 3) and Padi4−/− (n = 3) mice were analyzed by FACS. (e) Hematoxylin and eosin (HE) staining of Padi4-expressed tissues from the wild-type (WT) mouse, Padi4+/− (Heterozygote) mouse, and Padi4−/− (KO) mouse. (PDF 458 KB)
Additional file 3: of Piloting a generic cancer consumer quality index in six European countries
Creators: name: Wind, Anke
name: Roeling, Mark
name: Heerink, Jana
name: Sixma, Herman
name: Presti, Pietro
name: Lombardo, Claudio
name: Harten, Wim Van
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Problems per ECCQI-question. This file gives an overview of the problems identified per question during the cognitive interviews and through feedback on the questionnaire. (DOCX 20 kb)
Comprehensive design methodology for coal mining under competent sandstone roof
Creators: name: DuBois, Cale
Publisher: name: University of British Columbia
Year: 2009

description: This thesis presents a logical design methodology for coal mine extraction optimization under massive sandstone roof as developed though a case study analysis of the Quinsam Coal 4 South mine, a shallow underground room and pillar mine with a massive sandstone roof. This research is intended to guide Quinsam Coal and other coal mines globally in efforts to develop or optimize coal extraction and address the geomechanical challenges presented by massive sandstone roof. In this thesis, the tools required to facilitate effective site characterization, ground support design, excavation stability, pillar design, environmental risk management and mining method optimization are presented, as part of a comprehensive design methodology. Guidelines for pillar design are presented based on software assisted gravity-wedge analysis, and review of empirical and analytical design methods. Tools for addressing temporal change in pillar size, shape and stress as well as pillar jointing effects are provided. Pillars are designed to accommodate stresses and strains arising from the known range of overburden depths. An optimized non-caving checkerboard partial pillar extraction method is presented to mitigate environmental risk, address the poor and unpredictable caving mechanics of the massive sandstone roof and provide adequate coal extraction. Modeling of in-line pillar mining and checkerboard partial pillar mining methods was completed with ExamineTAB, a pseudo-3D displacement discontinuity program in support of checkerboard partial pillar mining. Instructional training is required with any modification in mining methods or conditions to apprise the underground workforce on the technical details of the mine design and the importance of adhering to the standards thereof. Using this research work and analysis of the 4 South mine as a backdrop, the design of coal mines under massive sandstone roof is facilitated. The application of the design methodology to the 4 South mine illustrated serves as a 'terms of reference' document for other professionals addressing similar geotechnical and environmental challenges to design safe coal pillar extraction under a massive sandstone roof.
Additional file 3: of Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice
Creators: name: Suzuki, Akari
name: Kochi, Yuta
name: Shoda, Hirofumi
name: Seri, Yu
name: Fujio, Keishi
name: Sawada, Tetsuji
name: Yamada, Ryo
name: Yamamoto, Kazuhiko
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Plant Biology

description: Padi2 and Padi4 are expressed in the spleens of wild-type mice. (a–e) Immunofluorescence staining (×40) shows that Padi2 is expressed ubiquitously in the spleen. Spleens were probed with anti-Padi2 (green fluorescent signal) and cell surface markers (red fluorescence signal; a, CD3; b, B220; c, Gr-1; d, CD56; e, F4/80). The nuclei were stained with DAPI (blue fluorescence signal). The arrows indicate the colocalization of Padi2 and each cell surface marker. (f–k) Immunofluorescence staining (×40) shows that Padi4 was expressed in splenocytes. The spleens were probed with anti-Padi4 (green fluorescence signal), and cell surface markers (red fluorescence signal; f, CD3; g, B220; h, Gr-1; i, CD56; j, F4/80). Nuclei were stained with DAPI (blue fluorescence signal). (K) Immunofluorescence staining (left, ×40; right, ×280) shows that Padi4 was localized in both the nuclei and cytoplasm of macrophages, which expressed F4/80. (PDF 286 KB)
Additional file 1: Figure S1. of Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy
Creators: name: Barini, Erica
name: Antico, Odetta
name: Yingjun Zhao
name: Asta, Francesco
name: Tucci, Valter
name: Catelani, Tiziano
name: Marotta, Roberto
name: Huaxi Xu
name: Gasparini, Laura
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Expression levels of key molecules in the insulin pathway in WT and P301S mouse cortex. Figure S2. Expression levels of key molecules in the insulin pathway in the cortex of P301S mouse treated with or without metformin. Figure S3. Expression levels of AMPK, S6, pS6, and tau in primary cortical neurons treated with or without metformin and/or specific blockers. Figure S4. Body weight, glycemia, water and food consumption in P301S mice treated with or without metformin. Table S1. Concentration of metformin in the plasma and brain of WT and P301S mice after treatment for 7 days. Table S2. Neuronal viability after pharmacological treatment for 6 h. Table S3. Primers used for qRT-PCR. (PDF 5110 kb)
LGBTQ+ Youth Therapeutic Engagement and Experiences: Associations with LGBTQ+ Family Environment
Creators: name: Zheng, Azure
Publisher: name: Digital Repository at the University of Maryland
Year: 2024
Subjects: subject: Mental health
subject: Health sciences
subject: FOS: Health sciences
subject: LGBTQ studies
subject: LGBTQ+ Youth
subject: LGBTQ+-Parenting
subject: Therapeutic Experience
subject: Therapy Engagement

description: LGBTQ+ youth experience unique stressors that increase the risk for poor mental health. LGBTQ+ youth’s family environment, often measured as parental acceptance and rejection of youth’s LGBTQ+ status, is associated with youth mental health; less often studied is how the family environment may be linked to LGBTQ+ youth’s access to therapy and, more importantly, experiences with LGBTQ+ affirmative and competent providers. Using a contemporary non-probability national sample of LGBTQ+ youth ages 13-17, our study examined the association among LGBTQ+ youth’s reports of caregiver supportive and rejection behaviors related to their LGBTQ+ identity and youth’s engagement and experiences in therapy. Using a step-wise logistic regression method, results tell a clear story. There is a consistent positive association between parent’s LGBTQ+ support behaviors and (1) youth access to therapy and (2) their therapists' LGBTQ+ competency. In the absence of controls, we found that parents’ rejecting behaviors were also positively associated with the youth’s access to therapy, but this relationship was mediated by the youth’s depression and anxiety symptoms. For youth who did not access therapy in the last year, those who reported more parental support were inversely related, and parental rejection positively related to wanting therapy but not receiving it. Youth who reported more rejecting behaviors from parents were less likely to perceive their therapists as LGBTQ+ competent. Findings point to varied pathways and experiences in therapy engagement for LGBTQ+ youth based on parents' support of their LGBTQ+ identity.
Additional file 1: of Piloting a generic cancer consumer quality index in six European countries
Creators: name: Wind, Anke
name: Roeling, Mark
name: Heerink, Jana
name: Sixma, Herman
name: Presti, Pietro
name: Lombardo, Claudio
name: Harten, Wim Van
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Overview of results per question and country. This files gives the answers to each question per country, both in absolute numbers (how many patients gave that specific answer) and percentage. (DOCX 103 kb)
Additional file 1: of Rethinking the assessment of risk of bias due to selective reporting: a cross-sectional study
Creators: name: Page, Matthew
name: Higgins, Julian
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer

description: Supplementary tables. (DOCX 57Â kb)
Additional file 1 of Let this be a safe place: a qualitative study into midwifery care for forcibly displaced women in the Netherlands
Creators: name: Tankink, J. B.
name: Verschuuren, A. E. H.
name: de Graaf, J. P.
name: Feijen-de Jong, E. I.
name: van der Lans, P. J. A.
name: van den Muijsenbergh, M. E. T. C.
name: Franx, A.
name: Goodarzi, B.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Biotechnology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1.
ALTERNATIVE CHOREOGRAPHIES: IMMERSIVE PERFORMANCE AS A DECOLONIAL PEDAGOGICAL AND PERFORMANCE PRACTICE
Creators: name: Padilla Garcia, Javier Ignacio
Publisher: name: Digital Repository at the University of Maryland
Year: 2024
Subjects: subject: Dance
subject: Performing arts

description: The research unfolds through a multidisciplinary lens, weaving together theoretical analysis, artistic creation, pedagogical exploration and performative interventions. Through “el bodegon de la bruja”, an interdisciplinary immersive dance theater performance, this thesis aims to explore alternative ways of understanding, learning, and expressing that are rooted in decolonial principles. The performance engages with diverse mediums and techniques to construct immersive environments that prompt participants to critically reflect on colonial histories and power structures. Through a series of performative acts and pedagogical interventions, the thesis seeks to demonstrate how immersive performance can serve as a conduit for decolonial praxis. The outcomes contribute to an evolving discourse on the potential of artistic and educational practices to actively dismantle colonial legacies. This work not only envisions alternative narratives but actively engages participants in co-creating knowledge, fostering a sense of empowerment, agency, and a deeper understanding of decolonialized perspectives.
Additional file 5: of Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice
Creators: name: Suzuki, Akari
name: Kochi, Yuta
name: Shoda, Hirofumi
name: Seri, Yu
name: Fujio, Keishi
name: Sawada, Tetsuji
name: Yamada, Ryo
name: Yamamoto, Kazuhiko
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Cytokine mRNA expression in CD11b + macrophages in the spleen. CD11b + wild-type (n = 19) and Padi4−/− CIA mice (n = 17) were used for 10 days from the day after booster injection. The cells were analyzed by real-time TaqMan RT-PCR for mRNA levels of (a) tumor necrosis factor alpha (TNF-α), (b) CSF-2, (c) IL-1β, (d) IL-6, and (e) IL-10. *P
PREDICTING THE SEISMIC SIGNATURE OF LAVA TUBES FOR THE EARTH, THE MOON, AND MARS
Creators: name: Wike, Linden
Publisher: name: Digital Repository at the University of Maryland
Year: 2024
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geophysics
subject: Planetology
subject: Lava Tubes
subject: Mesh
subject: Seismology
subject: Simulation
subject: Synthetic
subject: Wavefield

description: Lava tubes are a type of volcanically-generated subsurface void structure found on Earth, the Moon, and Mars and hold the potential to serve as shelters for crew members, preservation sites of pristine geological samples, and locations of in situ resources. A key question for lava tube science is how to locate them through geophysical methods. Here, we create a workflow that locates and characterizes the geometry of subsurface voids. We build a suite of subsurface synthetic seismic wavefield models that contain lava tube structures and investigate which seismic method best images them. Our models show that the more readily detectable lava tube simulations have a geophone spacing of 0.5 m, variable diameter, and shallow ceiling depth; and reverse-time migration and phase-shift-plus-interpolation migration techniques produce more accurate lava tube reconstructions than the Kirchhoff method. The synthetic modeling serves as a benchmark for understanding seismic wave propagation around lava tubes and helps answer how voids on the Moon and Mars would be imaged through seismology.
MOESM1 of Metformin improves the angiogenic potential of human CD34+ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction
Creators: name: Sherin Bakhashab
name: Ahmed, Fahad
name: Hans-Juergen Schulten
name: Ayat Bashir
name: Karim, Sajjad
name: Abdulrahman Al-Malki
name: Mamdooh Gari
name: Abuzenadah, Adel
name: Adeel Chaudhary
name: Alqahtani, Mohammed
name: Lary, Sahira
name: Ahmed, Farid
name: Weaver, Jolanta
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: Computational Biology

description: Additional file 1: Figure S1. Cell viability assay on HUVEC treated with sunitinib. Figure S2. Effect of metformin on euglycemia-hypoxia treated CD34+ cells. Figure S3. Validation of selected pro-angiogenic factors and angiogenic inhibitors in CD34+ cells by qRT-PCR. Figure S4. Heatmap of the pro-angiogenic and angiogenic inhibitors in CD34+ stem cells. Table S1. Effect of 3 h hypoxia on biological functions involved in CD34+ cells. Table S2. Top 30 differentially expressed genes in CD34+ cells induced by hyperglycemia compared to control. Table S3. Top biological functions involved in CD34+ cells cultured in hyperglycemia. Table S4. Top canonical pathways involved in CD34+ cells cultured in hyperglycemia. Table S5. Top 30 differentially expressed genes in CD34+ cells induced by hyperglycemia and treated with metformin compared to hyperglycemia. Table S6. Effect of metformin on canonical pathways involved in CD34+ cells cultured in combined hyperglycemia-hypoxia for 3 h. Table S7. Comparison of microarray and real-time PCR data on CD34+ cells treated with hypoxia, hyperglycemia and hyperglycemia-hypoxia in the presence and absence of metformin.
THE FORMATION AND EVOLUTION OF BOOK CENSORSHIP IN THE QING DYNASTY: A STUDY OF THE PUBLISHING INDUSTRY ON SIBAO
Creators: name: Wang, Liguan
Publisher: name: Digital Repository at the University of Maryland
Year: 2024
Subjects: subject: Asian history

description: This thesis emphasizes the formation and evolution of book censorship in the Qing dynasty and the impact of censorship on the choice of publications made by publishers in different regions. Book censorship in the Qing dynasty emerged in the early 17th century and was institutionalized, reaching its peak in the mid-to-late 18th century. Along with the development of censorship, the publishing centers around the major cities declined, and publishing centers away from the major cities, represented by the Sibao, began to emerge. Legal cases on censorship and distinctions between publications in different regions reveal the close relationship between censorship and the publishing industry. By reconsidering the publishing history of Sibao within the censorship framework, this thesis reveals how Sibao grew and developed under the Qing Dynasty's strict censorship, especially during the Qianlong period. This thesis examines censorship and the publishing industry during the Qing dynasty and contributes insights into the causes of the changing trends that arose at the center of publishing during the Qing dynasty.
Additional file 2 of Let this be a safe place: a qualitative study into midwifery care for forcibly displaced women in the Netherlands
Creators: name: Tankink, J. B.
name: Verschuuren, A. E. H.
name: de Graaf, J. P.
name: Feijen-de Jong, E. I.
name: van der Lans, P. J. A.
name: van den Muijsenbergh, M. E. T. C.
name: Franx, A.
name: Goodarzi, B.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Biotechnology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2.