cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Combined Influence of Magnesium and Insulin on Central Metabolic Functions and Expression of Genes Involved in Magnesium Homeostasis of Cultured Bovine Adipocytes
Creators: name: Becker, Sandra K.
name: Sponder, Gerhard
name: Sandhu, Mansur A.
name: Trappe, Susanne
name: Kolisek, Martin
name: Aschenbach, Jörg R.
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: magnesium
subject: insulin
subject: lipomobilization
subject: adipocytes
subject: cattle
subject: adipose tissue
subject: ketosis
subject: fatty liver
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::636 Viehwirtschaft

description: At the onset of lactation, dairy cows suffer from insulin resistance, insulin deficiency or both, similar to human diabetes, resulting in lipolysis, ketosis and fatty liver. This work explored the combined effects of different levels of magnesium (0.1, 0.3, 1 and 3 mM) and insulin (25, 250 and 25,000 pM) on metabolic pathways and the expression of magnesium-responsive genes in a bovine adipocyte model. Magnesium starvation (0.1 mM) and low insulin (25 pM) independently decreased or tended to decrease the accumulation of non-polar lipids and uptake of the glucose analog 6-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-6-deoxyglucose (6-NBDG). Activity of glycerol 3-phosphate dehydrogenase (GPDH) was highest at 25 pM insulin and 3 mM magnesium. Expression of SLC41A1 and SLC41A3 was reduced at 0.1 mM magnesium either across insulin concentrations (SLC41A1) or at 250 pM insulin (SLC41A3). MAGT1 expression was reduced at 3 mM magnesium. NIPA1 expression was reduced at 3 mM and 0.1 mM magnesium at 25 and 250 pM insulin, respectively. Expression of SLC41A2, CNNM2, TRPM6 and TRPM7 was not affected. We conclude that magnesium promotes lipogenesis in adipocytes and inversely regulates the transcription of genes that increase vs. decrease cytosolic magnesium concentration. The induction of GAPDH activity by surplus magnesium at low insulin concentration can counteract excessive lipomobilization.
The TRPA1 Agonist Cinnamaldehyde Induces the Secretion of HCO3− by the Porcine Colon
Creators: name: Manneck, David
name: Manz, Gisela
name: Braun, Hannah-Sophie
name: Rosendahl, Julia
name: Stumpff, Friederike
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: cinnamaldehyde
subject: colon
subject: colonic buffering
subject: epithelial transport
subject: essential oils
subject: intestine
subject: patch clamp
subject: pig
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::636 Viehwirtschaft
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik

description: A therapeutic potential of the TRPA1 channel agonist cinnamaldehyde for use in inflammatory bowel disease is emerging, but the mechanisms are unclear. Semi-quantitative qPCR of various parts of the porcine gastrointestinal tract showed that mRNA for TRPA1 was highest in the colonic mucosa. In Ussing chambers, 1 mmol·L−1 cinnamaldehyde induced increases in short circuit current (ΔIsc) and conductance (ΔGt) across the colon that were higher than those across the jejunum or after 1 mmol·L−1 thymol. Lidocaine, amiloride or bumetanide did not change the response. The application of 1 mmol·L−1 quinidine or the bilateral replacement of 120 Na+, 120 Cl− or 25 HCO3− reduced ΔGt, while the removal of Ca2+ enhanced ΔGt with ΔIsc numerically higher. ΔIsc decreased after 0.5 NPPB, 0.01 indometacin and the bilateral replacement of 120 Na+ or 25 HCO3−. The removal of 120 Cl− had no effect. Cinnamaldehyde also activates TRPV3, but comparative measurements involving patch clamp experiments on overexpressing cells demonstrated that much higher concentrations are required. We suggest that cinnamaldehyde stimulates the secretion of HCO3− via apical CFTR and basolateral Na+-HCO3− cotransport, preventing acidosis and damage to the epithelium and the colonic microbiome. Signaling may involve the opening of TRPA1, depolarization of the epithelium and a rise in PGE2 following a lower uptake of prostaglandins via OATP2A1.
Estimating Electric Fields from Vector Magnetogram Sequences
Creators: name: Fisher, G. H.
name: Welsch, B. T.
name: Abbett, W. P.
name: Bercik, D. J.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Determining the electric field (E-field) distribution on the Sun's photosphere is essential for quantitative studies of how energy flows from the Sun's photosphere, through the corona, and into the heliosphere. This E-field also provides valuable input for data-driven models of the solar atmosphere and the Sun-Earth system. We show how Faraday's Law can be used with observed vector magnetogram time series to estimate the photospheric E-field, an ill-posed inversion problem. Our method uses a "poloidal-toroidal decomposition" (PTD) of the time derivative of the vector magnetic field. The PTD solutions are not unique; the gradient of a scalar potential can be added to the PTD E-field without affecting consistency with Faraday's Law. We present an iterative technique to determine a potential function consistent with ideal MHD evolution; but this E-field is also not a unique solution to Faraday's Law. Finally, we explore a variational approach that minimizes an energy functional to determine a unique E-field, similar to Longcope's "Minimum Energy Fit". The PTD technique, the iterative technique, and the variational technique are used to estimate E-fields from a pair of synthetic vector magnetograms taken from an MHD simulation; and these E-fields are compared with the simulation's known electric fields. These three techniques are then applied to a pair of vector magnetograms of solar active region NOAA AR8210, to demonstrate the methods with real data.
description: 41 pages, 10 figures
title: Ð¤Ð»ÑÐºÑÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐµ ÐºÐ¾Ð»ÐµÐ±Ð°Ð½Ð¸Ñ Ð² ÑÐ°Ð´Ð¸Ð¾ÑÐ¸Ð·Ð¸ÐºÐµ
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ°Ð¹ÑÐµÐ², Ð­ÑÐ½ÑÑ
Publisher: name: ÐÐÐ¢Ð£
Year: 1990
Subjects: Ð Ð°Ð´Ð¸Ð¾ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½Ð°Ñ Ð°Ð¿Ð¿Ð°ÑÐ°ÑÑÑÐ°

description: Ð¡Ð¾Ð´ÐµÑÐ¶Ð°Ð½Ð¸Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð¾ÑÐ²Ð°ÑÑÐ²Ð°ÐµÑ Ð¾Ð´Ð¸Ð½ Ð¸Ð· ÑÐ°Ð·Ð´ÐµÐ»Ð¾Ð² ÐºÑÑÑÐ° "ÐÑÐ½Ð¾Ð²Ñ ÑÐ°Ð´Ð¸Ð¾ÑÐ¸Ð·Ð¸ÐºÐ¸" Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÐ¸ "Ð Ð°Ð´Ð¸Ð¾ÑÐ¸Ð·Ð¸ÐºÐ° Ð¸ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ°". ÐÐ°Ð½Ñ Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼ÑÐµ ÑÐ²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¿Ð¾ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð¼Ñ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ ÑÐ»ÑÐºÑÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÐºÐ¾Ð»ÐµÐ±Ð°Ð½Ð¸Ð¹ Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð·Ñ ÑÑÐ¼Ð¾Ð² Ð² Ð»Ð¸Ð½ÐµÐ¹Ð½ÑÑ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð°Ñ ÑÐ°Ð´Ð¸Ð¾ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ¸. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð° Ð¿ÑÐ¸ÑÐ¾Ð´Ð° ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð³Ð¾ Ð¸ Ð´ÑÐ¾Ð±Ð¾Ð²Ð¾Ð³Ð¾ ÑÑÐ¼Ð°, Ð²ÑÐ²ÐµÐ´ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð·Ð°ÐºÐ¾Ð½Ð¾Ð¼ÐµÑÐ½Ð¾ÑÑÐ¸. ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð²Ð°Ð¶Ð½ÐµÐ¹ÑÐ¸Ðµ ÑÑÐ¼Ð¾Ð²ÑÐµ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ ÑÐµÑÑÑÐµÑÐ¿Ð¾Ð»ÑÑÐ½Ð¸ÐºÐ¾Ð², ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¾ ÐºÑ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ Ðº ÑÐ°ÑÑÐµÑÑ Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ñ ÑÐ¸Ð³Ð½Ð°Ð»/ÑÑÐ¼ Ð² ÑÐ°Ð´Ð¸Ð¾Ð¿ÑÐ¸ÐµÐ¼Ð½ÑÑ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð°Ñ. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ Ð·Ð°Ð´Ð°ÑÐ¸ Ñ ÑÐµÑÐµÐ½Ð¸ÑÐ¼Ð¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð»Ð°Ð±Ð¾ÑÐ°ÑÐ¾ÑÐ½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ "Ð¨ÑÐ¼Ñ Ð² Ð¿Ð°ÑÑÐ¸Ð²Ð½ÑÑ Ð¸ Ð°ÐºÑÐ¸Ð²Ð½ÑÑ ÑÐµÐ¿ÑÑ".
description: ÐÐµÑÐ°ÑÐ°ÐµÑÑÑ Ð¿Ð¾ ÑÐµÑÐµÐ½Ð¸Ñ ÑÐµÐ´Ð°ÐºÑÐ¸Ð¾Ð½Ð½Ð¾-Ð¸Ð·Ð´Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ ÑÐ¾Ð²ÐµÑÐ° ÐÐµÐ½Ð¸Ð½Ð³ÑÐ°Ð´ÑÐºÐ¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ°.
Enhancing the rights of protection-seeking migrants through the Global Compact for Migration: the case of EU asylum policy
Creators: name: Bast, Jürgen
name: de Oliveira, Pauline Endres
name: Wessels, Janna
Publisher: name: Zenodo
Year: 2023
Subjects: Global Compact for Safe, Orderly and Regular Migration
Global Compact on Refugees
EU
PROTECT Consortium

description: In this paper, we argue that the Global Compact for Safe, Orderly and Regular Migration (GCM) is not only a breakthrough for a rights-based approach in international migration governance but also an asset to the international protection system – that is, the legal and political regime concerning refugees and other persons seeking international protection. The parallel emergence of the Global Compact on Refugees (GCR), situated in the pre-existing international protection system with the Refugee Convention of 1951 at its core, may suggest otherwise, namely, that the GCM is not relevant for refugees and other protection-seeking migrants. The authors of this paper challenge this assumption. We claim that the GCM can enhance the rights of persons in need of international protection, both within and outside the scope of the refugee definition provided in the Refugee Convention.
 To make our point, we use the EU as a test case. We shall demonstrate that the GCM has major policy implications in European asylum policy if the commitments laid down in the Migration Compact were taken seriously. By way of example, we shall discuss three key issues of the Common European Asylum System (CEAS): access to protection, reception conditions, and detention. Viewing current EU policies on these matters through the lens of the pertinent GCM Objectives, the relevance of the GCM’s contents can readily be identified. We will demonstrate that States have undertaken, according to the GCM, to broaden the scope of alternative pathways to protection, to secure economic and social rights of all migrants regardless of their protection status, and to work towards ending the use of detention as a means of asylum policy. Against this backdrop, faithfully implementing the GCM would require the EU and its Member States to make significant policy changes. Since their current policies are hardly exotic in the Global North, it seems safe the conclude the GCM more generally has the potential to enhance the rights of protection-seeking migrants and to strengthen the international protection system.
Ethiopia – Land, energy, climate change, and agricultural development: A study in the Sudano-Sahel Initiative for Regional Development, Jobs, and Food Security
Creators: name: Admassie, Assefa
name: Abebaw, Degnet
name: Admassie, Assefa
name: Abebaw, Degnet
Publisher: name: Unknown
Year: 2021
Subjects: subject: Agricultural and Food Policy
subject: Environmental Economics and Policy
subject: Resource /Energy Economics and Policy
subject: Ethiopia
subject: food insecurity
subject: biomass energy
subject: agricultural development
subject: land degradation
subject: climate change
subject: policy responses

description: Ethiopia is the second most populous country in Sub-Saharan Africa with a population of more than 110 million. With over 10 percent growth rate, the Ethiopian economy has been one of the fastest growing economies in the world over the last one and half decades. By any measure agriculture is the dominant economic sector in the country accounting for a sizeable portion of the GDP growth, generating most of the export earnings and employing most of the labour force. The country has diverse agro-ecological conditions which are suitable for growing both temperate and tropical food and industrial crops. This study has tried to review the trends in environment conditions such as energy use, land cover and land use changes as well as the impact of climate change and the policy responses of the Government of Ethiopia. The review clearly shows that Ethiopia is still a poor country with more than one fifth of the population living below the national poverty line. Food insecurity continues to be a big challenge for millions of Ethiopians. Despite being the dominant economic sector, agricultural production is characterized as a low-input-low productivity sector. Land degradation is a very serious problem in Ethiopia due to the fact that many parts of the Ethiopian highlands are mountainous and rugged. Even though Ethiopia has huge potential for generating renewable energy, the majority of the Ethiopian population still relies on biomass energy sources such as wood, animal dung and crop residues. These environmental challenges are also exacerbated due to the effect of climate change. To mitigate the impact of land degradation, deforestation, and climate change, the Government of Ethiopia has formulated and implemented several policies. The Agricultural Growth Program (AGP), the Productive Safety Net Program (PSNP), the Sustainable Land Management Program (SLM) and the Climate Resilient Green Economy (CRGE) strategy are the major programs being implemented to address these environmental challenges. Indeed, these interventions have made noticeable contributions to curb the challenges.
Measuring the beaming angle of GRB 030329 by fitting the rebrightenings in its multiband afterglow
Creators: name: Deng, Wei
name: Huang, Yong-Feng
name: Kong, Si-Wei
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Multiple rebrightenings have been observed in the multiband afterglow of GRB 030329. Especially, a marked and quick rebrightening occurred at about t ~ 1.2 * 10^5 s. Energy injection from late and slow shells seems to be the best interpretation for these rebrightenings. Usually it is assumed that the energy is injected into the whole external shock. However, in the case of GRB 030329, the rebrightenings are so quick that the usual consideration fails to give a satisfactory fit to the observed light curves. Actually, since these late/slow shells coast freely in the wake of the external shock, they should be cold and may not expand laterally. The energy injection then should only occur at the central region of the external shock. Considering this effect, we numerically re-fit the quick rebrightenings observed in GRB 030329. By doing this, we were able to derive the beaming angle of the energy injection process. Our result, with a relative residual of only 5% - 10% during the major rebrightening, is better than any previous modeling. The derived energy injection angle is about 0.035. We assume that these late shells are ejected by the central engine via the same mechanism as those early shells that produce the prompt gamma-ray burst. The main difference is that their velocities are much slower, so that they catch up with the external shock very lately and manifest as the observed quick rebrightenings. If this were true, then the derived energy injection angle can give a good measure of the beaming angle of the prompt gamma-ray emission. Our study may hopefully provide a novel method to measure the beaming angle of gamma-ray bursts.
description: 8 pages, 6 figures, Has been accepted by RAA (Research in Astronomy and Astrophysics)
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐ¸ÑÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ¸Ð»Ñ Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸ ÐÐÐ Â«ÐÑÐ¾Ð¼ ÐÐ¼Ð¿ÑÐ»ÑÑÂ»
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐµÐ»Ð¾Ð·ÐµÑÐ¾Ð²Ð°, ÐÐ»ÐµÐ½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÐ¸ÑÐ¼ÐµÐ½Ð½ÑÐ¹ ÑÑÐ¸Ð»Ñ
ÑÑÐ½Ð¾Ðº ÑÐµÐ¿Ð»Ð¾ÑÐ½Ð°Ð±Ð¶ÐµÐ½Ð¸Ñ
Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½ÑÐµ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð° ÑÑÑÐ½Ð¾ÑÑÑ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð° Ðº ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÑÐ¸ÑÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ¸Ð»Ñ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½Ð¾Ð¹ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐµÐ¹ ÑÑÐ½ÐºÐ°. ÐÐ°Ð½Ñ Ð¾Ð±ÑÐ¸Ðµ Ð¿Ð¾Ð½ÑÑÐ¸Ñ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² ÑÐ¸ÑÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ¸Ð»Ñ Ð¸ ÑÐ¿Ð¾ÑÐ¾Ð±Ð¾Ð² Ð¾ÑÐµÐ½ÐºÐ¸ ÐµÐ³Ð¾ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐÐÐ Â«ÐÑÐ¾Ð¼ ÐÐ¼Ð¿ÑÐ»ÑÑÂ». Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð° ÐµÐ³Ð¾ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð°Ñ ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½ ÐµÐ³Ð¾ ÑÐ¸ÑÐ¼ÐµÐ½Ð½ÑÐ¹ ÑÑÐ¸Ð»Ñ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ ÑÑÐ´ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¹ Ð¿Ð¾ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ ÑÐ¸ÑÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ¸Ð»Ñ Ñ Ð¿ÑÐ¸Ð¼ÐµÑÐ°Ð¼Ð¸, ÑÐ°ÐºÐ¶Ðµ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½ Ð¿Ð»Ð°Ð½ Ð²Ð½ÐµÐ´ÑÐµÐ½Ð¸Ñ Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐ° ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ¸Ð»Ñ Ð´Ð»Ñ ÐÐÐ Â«ÐÑÐ¾Ð¼ ÐÐ¼Ð¿ÑÐ»ÑÑÂ».
Confirming the factor structure of the general and political health scales
Creators: name: Hopp, Frederic R.
name: Schumacher, Gijs
name: Bakker, Bert N.
name: Peterson, Delaney
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences

description: This registration contains a pre-analysis plan titled: Confirming the factor structure of the general and political health scales.
Iterative Solution of the Quasicontinuum Equilibrium Equations with Continuation
Creators: name: Dobson, Matthew
name: Luskin, Mitchell
Publisher: name: arXiv
Year: 2008
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65Z05, 70C20

description: We give an analysis of a continuation algorithm for the numerical solution of the force-based quasicontinuum equations. The approximate solution of the force-based quasicontinuum equations is computed by an iterative method using an energy-based quasicontinuum approximation as the preconditioner. The analysis presented in this paper is used to determine an efficient strategy for the parameter step size and number of iterations at each parameter value to achieve a solution to a required tolerance. We present computational results for the deformation of a Lennard-Jones chain under tension to demonstrate the necessity of carefully applying continuation to ensure that the computed solution remains in the domain of convergence of the iterative method as the parameter is increased. These results exhibit fracture before the actual load limit if the parameter step size is too large.
description: 22 pages, 8 figures
Do Hernias Contribute to Increased Severity of Aneurysmal Disease among Abdominal Aortic Aneurysm Patients?
Creators: name: Hinterseher, Irene
name: Miszczuk, Milena
name: Corvinus, Florian
name: Zimmermann, Carolin
name: Estrelinha, Mariana
name: Smelser, Diane T.
name: Kuivaniemi, Helena
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: abdominal aortic aneurysm
subject: hernia
subject: connective tissue disorder
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Connective tissue disorders could contribute to the pathogenesis of both abdominal aortic aneurysms (AAA) and hernias. We tested the hypothesis that hernias in AAA patients contribute to increased severity of the aneurysmal disease. Methods: A questionnaire was used to collect information from 195 AAA patients divided into four groups: (1) survivors (n = 22) of ruptured AAA, (2) patients (n = 90) after elective open repair, (3) patients (n = 43) after elective endovascular repair (EVAR), and (4) patients (n = 40) under surveillance of AAA. The control group consisted of 100 patients without AAA whose abdominal computed tomography (CT) scans were examined for the presence of hernias. Mann-Whitney U-test, Chi-squared (χ 2) test, or Fisher's exact test (as appropriate) were used for statistical analyses. Multivariate logistic regression was used to control for potential confounding variables such as sex and age. Results: The prevalence of inguinal hernias was significantly higher in the AAA than the control group (25 vs. 9%, p = 0.001) and did not differ between the AAA subgroups (9, 24, 35, and 23% in subgroups 1 through 4, respectively, p = 0.15) based on univariate analysis. The prevalence of inguinal hernias did not differ (p = 0.15) between the two open surgery groups (groups 1 and 2), or when comparing all three operative procedures as a combined group to group 4 (p = 0.73). The prevalences of incisional hernias were 18 and 24% for groups 1 and 2, respectively, with no significant difference (p = 0.39). Inguinal hernia demonstrated a significant association with AAA on multivariate analysis (p = 0.006; odds ratio [OR] = 4.00; 95% confidence interval [CI] = 1.49-10.66). Conclusions: Our study confirms previous observations that patients with AAA have a high prevalence of hernias. Our results suggest that hernias do not contribute to increased severity of the aneurysmal disease.
Galactic C and S Stars as Guidelines for Magellanic Cloud AGB Stars
Creators: name: Guandalini, R.
name: Busso, M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The study of the evolutionary properties of Asymptotic Giant Branch stars still presents unresolved topics. Progress in the theoretical understanding of their evolution is hampered by the difficulty to empirically explain key physical parameters like their luminosity, mass loss rate and chemical abundances. We are performing an analysis of Galactic AGB stars trying to find constraints for these parameters. Our aim is of extending this analysis to the AGB stars of the Magellanic Clouds and of the Dwarf Spheroidal Galaxies using also mid-infrared observations from the Antarctic telescope IRAIT. AGB sources from the Magellanic Clouds will be fundamental in our understanding of the AGB evolution because they are all at a well defined distance (differently from the Galactic AGBs). Moreover, these sources present different values of metallicity: this fact should permit us of examining in a better way their evolutionary properties comparing their behaviour with the one from Galactic sources.
description: 4 pages, 3 figures. Proceeding of the IAU Symposium 256: The Magellanic System: Stars, Gas, and Galaxies. It is available online at http://www.astro.keele.ac.uk/iaus256/proceedings/
title: Ð¡ÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¼Ð¾ÑÑÐ¾ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÑ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹ Ñ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð¸ÑÐµÐ»ÑÐ½Ð¸Ñ ÑÐ»Ð¾Ð¶Ð½Ð¾ÐºÐ¾Ð¾ÑÐ´Ð¸Ð½Ð°ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð²Ð¸Ð´Ð¾Ð² ÑÐ¿Ð¾ÑÑÐ°
title: Comparative analysis of morphofunctional indicators in representatives of complex coordination sports
Creators: name: ÐÐ¾ÐºÐ¾ÑÐ¸Ð½Ð°, ÐÐ»ÐµÐ½Ð°
name: Ð¢ÐºÐ°ÑÑÐº, ÐÐ°ÑÐ¸Ð½Ð°
name: ÐÐµÑÐ¿Ð°Ð»Ð¾Ð²Ð°, ÐÑÐµÐ½Ð¸Ñ
name: "Ð¡Ð¿Ð¾ÑÑ, ÑÐµÐ»Ð¾Ð²ÐµÐº, Ð·Ð´Ð¾ÑÐ¾Ð²ÑÐµ", Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¹ Ð½Ð°ÑÑÐ½ÑÐ¹ ÐºÐ¾Ð½Ð³ÑÐµÑÑ
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2023
Subjects: Ð²ÑÑÐ¾ÐºÐ¾ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐµ ÑÐ¿Ð¾ÑÑÑÐ¼ÐµÐ½ÐºÐ¸
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highly qualified female athletes
figure skating
sports aerobics
anthropometry
model characteristics

description: Ð£ ÑÐ¿Ð¾ÑÑÑÐ¼ÐµÐ½Ð¾Ðº, Ð·Ð°Ð½Ð¸Ð¼Ð°ÑÑÐ¸ÑÑÑ ÑÐ¸Ð³ÑÑÐ½ÑÐ¼ ÐºÐ°ÑÐ°Ð½Ð¸ÐµÐ¼ Ð¸ ÑÐ¿Ð¾ÑÑÐ¸Ð²Ð½Ð¾Ð¹ Ð°ÑÑÐ¾Ð±Ð¸ÐºÐ¾Ð¹, Ð² Ð²Ð¾Ð·ÑÐ°ÑÑÐµ Ð¾Ñ 17 Ð´Ð¾ 19 Ð»ÐµÑ, Ð¸Ð¼ÐµÑÑÐ¸Ñ ÑÐ¿Ð¾ÑÑÐ¸Ð²Ð½Ð¾Ðµ Ð·Ð²Ð°Ð½Ð¸Ðµ ÐÐ¡, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ Ð°Ð½ÑÑÐ¾Ð¿Ð¾Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¾Ð±ÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ ÐºÐ¾Ð¼Ð¿Ð¾Ð½ÐµÐ½ÑÑ Ð¼Ð°ÑÑÑ ÑÐµÐ»Ð°, Ð¸Ð½Ð´ÐµÐºÑÑ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ, ÑÐ°Ð±Ð¾ÑÐ¾ÑÐ¿Ð¾ÑÐ¾Ð±Ð½Ð¾ÑÑÐ¸ Ð¸ Ð²ÐµÑÑÐ¸Ð±ÑÐ»ÑÑÐ½Ð¾Ð¹ ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÐ¸. Ð¡ÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ð´Ð°Ð½Ð½ÑÑ ÑÐ²Ð¸Ð´ÐµÑÐµÐ»ÑÑÑÐ²ÑÐµÑ, ÑÑÐ¾ Ð¼Ð¾Ð´ÐµÐ»ÑÐ½ÑÐµ Ð¼Ð¾ÑÑÐ¾ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÐµ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ¸ ÑÐ¿Ð¾ÑÑÑÐ¼ÐµÐ½Ð¾Ðº Ð²ÑÑÐ¾ÐºÐ¾Ð³Ð¾ ÐºÐ»Ð°ÑÑÐ°, Ð½ÐµÑÐ¼Ð¾ÑÑÑ Ð½Ð° Ð±Ð»Ð¸Ð·ÐºÐ¾ ÑÐ¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾ÑÑÑ ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¹, Ð´Ð¾ÑÑÐ¾Ð²ÐµÑÐ½Ð¾ Ð¾ÑÐ»Ð¸ÑÐ°ÑÑÑÑ Ð¿Ð¾ Ð±Ð¾Ð»ÑÑÐ¸Ð½ÑÑÐ²Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹.
description: Female athletes involved in figure skating and sports aerobics, aged 17 to 19 years, having the sports title of Master of Sports, have been examined for anthropometric indicators, physical development, performance and vestibular stability. A comparison of the data obtained indicates that the model morphofunctional characteristics of high-class athletes, despite the close relatedness of specializations, differ significantly in most indicators.
A Matter of Caution: Coagulation Parameters in COVID-19 Do Not Differ from Patients with Ruled-Out SARS-CoV-2 Infection in the Emergency Department
Creators: name: Bauer, Wolfgang
name: Galtung, Noa
name: Neuwinger, Nick
name: Kaufner, Lutz
name: Langer, Elisabeth
name: Somasundaram, Rajan
name: Tauber, Rudolf
name: Kappert, Kai
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: D-dimer
subject: COVID-19
subject: emergency department
subject: intensive care unit
subject: risk stratification
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: COVID-19 (coronavirus disease 2019) patients often show excessive activation of coagulation, associated with increased risk of thrombosis. However, the diagnostic value of coagulation at initial clinical evaluation is not clear. We present an in-depth analysis of coagulation in patients presenting to the emergency department (ED) with suspected COVID-19. N = 58 patients with clinically suspected COVID-19 in the ED were enrolled. N = 17 subsequently tested positive using SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) polymerase chain reaction (PCR) swabs, while in n = 41 COVID-19 was ruled-out. We analyzed both standard and extended coagulation parameters, including thromboplastin time (INR), activated partial thromboplastin time (aPTT), antithrombin, plasminogen, plasminogen activator inhibitor-1 (PAI-1), D-dimers, and fibrinogen at admission, as well as α2-antiplasmin, activated protein C -resistance, factor V, lupus anticoagulant, protein C, protein S, and von Willebrand diagnostics. These data, as well as mortality and further laboratory parameters, were compared across groups based on COVID-19 diagnosis and severity of disease. In patients with COVID-19, we detected frequent clotting abnormalities, including D-dimers. The comparison cohort in the ED, however, showed similarly altered coagulation. Furthermore, parameters previously shown to distinguish between severe and moderate COVID-19 courses, such as platelets, plasminogen, fibrinogen, aPTT, INR, and antithrombin, as well as multiple nonroutine coagulation analytes showed no significant differences between patients with and without COVID-19 when presenting to the ED. At admission to the ED the prevalence of coagulopathy in patients with COVID-19 is high, yet comparable to the non-COVID-19 cohort presenting with respiratory symptoms. Nevertheless, coagulopathy might worsen during disease progression with the need of subsequent risk stratification.
Dijital Sergi Konulu İnfografik Çalışması
Creators: name: Layık, Melek
Publisher: name: Zenodo
Year: 2019
Subjects: Dijital Sergi, İnteraktif Sergi

description: Teknolojinin gelişmesiyle ortaya çıkan 'Dijital Sergi' kavramı, sanatçıların ziyaretçilerine etkileşimli bir şekilde ürünlerini sunabilme fırsatını sağlamaktadır. 
An Overview of the Geomorphological Characteristics of the Pergamon Micro-Region (Bakırçay and Madra River Catchments, Aegean Region, West Turkey)
Creators: name: Yang, Xun
name: Becker, Fabian
name: Knitter, Daniel
name: Schütt, Brigitta
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: geomorphological map
subject: geomorphometry
subject: geomorphodynamics
subject: human-environment interaction
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::550 Geowissenschaften

description: Current landforms are the basis for understanding past geomorphodynamics and human activities. Based on multiple materials and methods, including geomorphometric analyses of a digital elevation model and visual interpretations of satellite images, different landscape units of the Bakırçay and Madra River catchments in the environs of ancient Pergamon are described. The area was mainly shaped by tectonics that formed a horst-and-graben structure; small Miocene horsts and NE-trending subgrabens in the Kozak and Yunt Dağı Mountains were separated by the NEE-trending Plio-Pleistocene Bergama Graben. The asymmetry in relief, drainage network, and sediment accumulation between the Kozak Mountains to the north and the Yunt Dağı Mountains to the south of the lower Bakırçay plain characterize the Pergamon Micro-Region. The regional relief characteristics, with wide flat basin and plateau areas, are suitable for agriculture. Complemented by its richness in natural resources, the Pergamon Micro-Region became a preferred settlement area, with evidence of human impact since the Hellenistic–Roman period at the latest. As a consequence of settlement activities, several landscape engineering measures were implemented simultaneously with a parallel change in morphodynamics.
Digitalisierung der Landwirtschaft: technologischer Stand und Perspektiven. TAB-Fokus
Creators: name: Kehl, Christoph
name: Meyer, Rolf
name: Steiger, Saskia
Publisher: name: Büro für Technikfolgen-Abschätzung beim Deutschen Bundestag (TAB)
Year: 2021
Subjects: Digitalisierung
Landwirtschaft
Technikfolgenabschätzung

description: Etliche innovative Agrartechnologien, die wesentlich auf digitaler Datenverarbeitung beruhen, sind bereits praxisreif oder in fortgeschrittener Entwicklung, darunter satellitengesteuerte Landmaschinen, Sensor- und Applikationstechniken mit variabler Dosierung von Dünge- und Pflanzenschutzmitteln oder Roboter für Melk-, Fütterungs- und Entmistungsvorgänge. Digitale Einzelanwendungen dieser Art erfassen große Mengen an Prozessdaten und bilden so die Grundlage für eine weitreichende Digitalisierung der landwirtschaftlichen Produktion. Der weitere Fortschritt bei den digitalen Agrartechnologien könnte zu grundlegenden Veränderungen der landwirtschaftlichen Prozesse führen, wie es beispielsweise im Bereich des Ackerbaus mit bestimmten Robotikkonzepten zu erwarten ist. Mithilfe der Digitalisierung sollen die komplexen, von vielen unwägbaren Faktoren beeinflussten landwirtschaftlichen Betriebsabläufe effizienter und gleichzeitig nachhaltiger ausgerichtet werden und in der Folge Umweltentlastungen bewirken. Zugleich erscheinen die digitalen Agrartechnologien allein nicht ausreichend bzw. teilweise nicht geeignet, um einige wichtige Umwelt- und Tierwohlprobleme der landwirtschaftlichen Produktion zu beheben.
D2.1.12– Final report on the analysis of the use of food composition data through the Use Case Approach (Task 10)
Creators: name: University of Surrey
name: Raats, Dr. Monique
Publisher: name: Zenodo
Year: 2005
Subjects: NoE and NEXUS Projects
The EuroFIR Food Platform
EuroFIR

description: 1. IntroductionA key objective of the EuroFIR project is increased internet availability of European national food composition data and specialised collections through a common access system (Møller, Unwin, Becker & Ireland, 2007). Two systems currently being developed within the EuroFIR project to facilitate this access are an E-search system and a database of bioactive compounds (E-BASIS). The development of a technical system typically encompasses gathering requirements, modelling the system’s functions, designing the product, building the system and using the product. Use cases provide a means of modelling and understanding a system’s functional requirements based on users’ ideas of what they want from the system. By focusing on the system’s users the emphasis is on how the system will be used instead of how it will be built or implemented (Cockburn, 2001). For the purposes of EuroFIR, the ‘Use Case’ approach has been adapted and employed to identify users’ needs when interacting with typical software systems to access and use food composition data as well as some of the key EuroFIR systems currently in development. Development of use cases will help to identify the essential functional requirements of these EuroFIR systems and may also help to identify any areas of opportunity for EuroFIR to add value to its systems in situations where the users’ needs are not currently being met, for example by facilitating access to data on branded foods. WP2.1b has identified a number of key ‘processes’ that are important for users of food composition data systems. The aim is to collect and structure the users’ requirements in the form of a documented ‘Use Case write-up’ for each of these specified key processes. This report extends the earlier work reported in M 2.1.7 and M 2.1.9 and fulfils the requirements of deliverable D 2.1.12.
Comment on "Measurement of x-ray absorption spectra of overdoped high-temperature cuprate superconductors: Inapplicability of the single-band Hubbard model"
Creators: name: Phillips, Philip
name: Jarrell, Mark
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In a recent Letter, Peets, et al. measured the x-ray intensity at the oxygen K-edge in overdoped La$_{2-x}$Sr$_x$CuO$_{4\pmδ}$ (LSCO) and Tl$_2$Ba$_2$CuO$_{6+δ}$. They claimed that, unlike the underdoped samples of LSCO and YBa$_2$Cu$_3$O$_x$ in which the integrated intensity increases at least linearly with doping, it saturates abruptly for a hole count exceeding $x\approx 0.23$. They interpreted the saturation as a breakdown of the 1-band Hubbard model in the cuprates. However, we show that their results are in quantitative agreement with the 1-band Hubbard model.
Is only one cognitive technique also effective? Results from a randomized controlled trial of two different versions of an internet-based cognitive behavioural intervention for post-traumatic stress disorder in Arabic-speaking countries
Creators: name: Böttche, Maria
name: Wagner, Birgit
name: Vöhringer, Max
name: Heinrich, Manuel
name: Stein, Jana
name: Selmo, Pirko
name: Stammel, Nadine
name: Knaevelsrud, Christine
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: PTSD
subject: trauma
subject: Arab
subject: Internet
subject: CBT
subject: e-mental health
subject: scalability
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: Background Internet-based cognitive-behavioural interventions seem to be effective for the treatment of posttraumatic stress disorder (PTSD) in Arabic-speaking countries in the MENA region. However, due to high prevalence rates of trauma-related mental disorders in this region, it is important to scale up existing Internet-based interventions in order to increase the number of clients. Objective The aim of the study was to examine whether a brief Internet-based intervention with one cognitive technique (TF-short, 6 assignments) results in the same PTSD symptom change and lower dropouts compared to a longer intervention with two cognitive techniques (TF-reg, 10 assignments). Method A total of 224 Arab participants (67.4% female; M = 25.3 years old) with PTSD were randomly assigned to Internet-based CBT with either a TF-reg protocol (n = 110) or a TF-short protocol (n = 114). Symptoms of PTSD and secondary outcomes (anxiety, depression, somatic complaints, quality of life) were self-assessed online at baseline and post-treatment. Treatment-associated changes were estimated using multigroup latent difference score models. Results The overall PTSD score assessed with the PDS decreased by about 15 points in both conditions. The between-group differences (TF-reg vs. TF-short) at post-assessment were non-significant, Δ = 0.29, p = .896, d = 0.02, 95% CI [-0.30, 0.34]. Like the primary outcome, all within-group changes for the secondary outcomes throughout the intervention were statistically significant and all between-group effects were non-significant. Overall, the dropout rates did not differ between the two conditions, χ2 (1/N = 175) = 0.83, p = .364. Conclusions The findings suggest that the shorter condition results in the same symptom change and dropout rate as the longer condition. This highlights the potential of shorter, more scalable Internet-based interventions in socially restricted and (post-)conflict societies.
title: ÐÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° ÐµÐ²ÑÐ¾Ð¿ÐµÐ¹ÑÐºÐ¾Ð¹ ÐºÑÑ Ð½Ð¸ Ð½Ð° 100 Ð¼ÐµÑÑ Ð² Ð¦ÐµÐ½ÑÑÐ°Ð»ÑÐ½Ð¾Ð¼ ÑÐ°Ð¹Ð¾Ð½Ðµ Ð³. Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³Ð°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¾ÑÐ¸Ð½, Ð Ð¾Ð¼Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÑÐµÑÑÐ¾ÑÐ°Ð½ ÐµÐ²ÑÐ¾Ð¿ÐµÐ¹ÑÐºÐ¾Ð¹ ÐºÑÑ Ð½Ð¸
Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð¼ÐµÐ½Ñ
ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ°ÑÑÐµÑÑ
ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸

description: ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¾ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ðµ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° ÐµÐ²ÑÐ¾Ð¿ÐµÐ¹ÑÐºÐ¾Ð¹ ÐºÑÑÐ½Ð¸, Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ°ÑÑÐµÑÑ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÑÑÑÐºÑÑÑÐ° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÑÐµÐ¼Ð¾Ð³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ, ÐµÐ³Ð¾ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð¾ÑÐ½Ð¾Ðµ ÑÐµÑÐµÐ½Ð¸Ðµ Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸.
High-quality ion beams from a nanometric double-layer target and their application to hadron-therapy
Creators: name: Grech, M.
name: Skupin, S.
name: Nuter, R.
name: Gremillet, L.
name: Lefebvre, E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: The production of ion beams from the interaction of a circularly polarized laser pulse with a nanometric double-layer target is discussed in the regime where all electrons are expelled from the target by laser radiation pressure. Quasi-monochromatic, well-collimated ion beams are observed in two-dimensional particle-in-cell simulations. The ion beam properties are derived from a simple analytical model, and the possibility to control those properties by using a laser-pulse with sharp-rising edge is discussed. Potential application to hadron-therapy is finally considered.
description: 5 pages, 2 figures, submitted as a proceeding of the Coulomb'09 workshop in a Special Issue of Nuclear Instruments and Methods in Physics Research - Section A
Dark Stars: the First Stars in the Universe may be powered by Dark Matter Heating
Creators: name: Freese, Katherine
name: Bodenheimer, Peter
name: Gondolo, Paolo
name: Spolyar, Douglas
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A new line of research on Dark Stars is reviewed, which suggests that the first stars to exist in the universe were powered by dark matter heating rather than by fusion. Weakly Interacting Massive Particles, which may be there own antipartmers, collect inside the first stars and annihilate to produce a heat source that can power the stars. A new stellar phase results, a Dark Star, powered by dark matter annihilation as long as there is dark matter fuel.
description: 6 pages, Eighth UCLA Symposium: Sources and Detection of Dark Matter and Dark Energy in the Universe, proceedings
The Legal Effects of the Global Compact for Safe, Orderly and Regular Migration: EU Development Policy and Irregular Migration Management
Creators: name: Guild, Elspeth
name: Grundler, Maja
Publisher: name: Zenodo
Year: 2022
Subjects: legal research
Global Compact for Safe, Orderly and Regular Migration
EU Development Policy
Irregular Migration Management
legal effects
PROTECT Consortium

description: The Global Compact for Safe, Orderly and Regular Migration (GCM) explicitly states that it ‘presents a non-legally binding, cooperative framework’. As a result, the GCM’s non-binding nature is not normally questioned. However, it has been pointed out that, even if legally non-binding, the GCM consolidates existing human rights obligations, which are legally binding upon states, contains a commitment to non-regression with regard to these standards, and, moreover, is politically binding. This means that rather than setting new standards, the GCM consolidates existing law, while spelling out how states should act in order to comply with this existing law.
 Framing the GCM, as well as its counterpart, the Global Compact on Refugees (GCR), as non-binding is likely to have contributed to governments endorsing both instruments. States may be more willing to endorse an instrument which is not considered to introduce any new obligations. Yet, a leaked 2019 document produced by the European Commission’s legal service, titled ‘The legal effects of the adoption of the Global Compact for Safe, Orderly and Regular Migration by the UN General Assembly’ suggests that, contrary to the predominant view that the GCM is non-binding, it has ‘legal effects’, specifically on EU development policy. While interpreting EU asylum law in line with GCM provisions and standards can serve to improve the rights of refugees, asylum-seekers and other migrants, the general view that the Compact is non-binding makes this an optional (though desirable) exercise. Suggesting that the Compact has legal effects on EU development policy, however, may lead to the conclusion that designing and interpreting legislation in this area in line with GCM standards ought to be mandatory. Thus, the GCM may have a much greater impact on states’ existing and future laws and policies than they thought it would.
 In this policy brief, we consider the Commission legal service’s arguments regarding the legal effects of the GCM. We argue that the legal service opinion has the potential to address the effects of the long-standing intrusion of policy on irregular migration into the realm of development policy and its damaging effects on the rights of (irregular) migrants. This, in turn, has implications for future policy in this area.
title: Fuoriuscite. Memorie al femminile dell'esilio antifascista
Creators: name: Fedele, Santi
Publisher: name: Humanities
Year: 2020

description: Esiste una specificità di genere nelle memorie dell’antifascismo in esilio? Certamente, e, per come si evince da questo breve saggio (anticipazione di un più vasto studio cui attende l’Autore), tale specificità va individuata in almeno tre ordini di fattori: la maggiore attenzione dedicata dalle donne, superando la dimensione prevalentemente politica delle memorie maschili, alla “quotidianità” dell’esperienza fuoruscita; la loro particolare considerazione di aspetti tutt’altro che marginali nella vicenda del fuoruscitismo quali i rapporti di coppia e, in taluni casi, con i figli; la loro speciale sensibilità verso i risvolti psicologici della condizione dell’esule. Le memorie che prendiamo in esame attengono a cinque antifasciste di diverso colore politico: Vera Funaro, moglie di uno dei più noti e prestigiosi esponenti dell’ala riformista del Partito socialista quale Giuseppe Emanuele Modigliani; Teresa Noce, figura di spicco del Partito comunista nell’esilio e nella clandestinità, coniugata al leader comunista Luigi Longo; Luce Fabbri, figlia del militante e pensatore anarchico Luigi; Joyce Salvadori, compagna di vita e di lotte di uno dei maggiori esponenti di Giustizia e Libertà quale Emilio Lussu; Lidia Campolonghi, figlia di Luigi, cofondatore con Alceste De Ambris della Lega italiana dei diritti dell’Uomo (Lidu).
description: Humanities, V. 9, N. 1 (2020)
El Nino Southern Oscillation as Sporadic Oscillations between Metastable States
Creators: name: Ma, Tian
name: Wang, Shouhong
Publisher: name: arXiv
Year: 2008
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The main objective of this article is to establish a new mechanism of the El Nino Southern Oscillation (ENSO), as a self-organizing and self-excitation system, with two highly coupled processes. The first is the oscillation between the two metastable warm (El Nino phase) and cold events (La Nina phase), and the second is the spatiotemporal oscillation of the sea surface temperature (SST) field. The interplay between these two processes gives rises the climate variability associated with the ENSO, leads to both the random and deterministic features of the ENSO, and defines a new natural feedback mechanism, which drives the sporadic oscillation of the ENSO. The new mechanism is rigorously derived using a dynamic transition theory developed recently by the authors, which has also been successfully applied to a wide range of problems in nonlinear sciences.
Profilin Isoforms in Health and Disease – All the Same but Different
Creators: name: Murk, Kai
name: Ornaghi, Marta
name: Schiweck, Juliane
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: profilin
subject: actin
subject: cytoskeleton
subject: central nervous system
subject: amyotrophic lateral sclerosis
subject: Fragile X syndrome
subject: Huntington's disease
subject: spinal muscular atrophy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Profilins are small actin binding proteins, which are structurally conserved throughout evolution. They are probably best known to promote and direct actin polymerization. However, they also participate in numerous cell biological processes beyond the roles typically ascribed to the actin cytoskeleton. Moreover, most complex organisms express several profilin isoforms. Their cellular functions are far from being understood, whereas a growing number of publications indicate that profilin isoforms are involved in the pathogenesis of various diseases. In this review, we will provide an overview of the profilin family and "typical" profilin properties including the control of actin dynamics. We will then discuss the profilin isoforms of higher animals in detail. In terms of cellular functions, we will focus on the role of Profilin 1 (PFN1) and Profilin 2a (PFN2a), which are co-expressed in the central nervous system. Finally, we will discuss recent findings that link PFN1 and PFN2a to neurological diseases, such as amyotrophic lateral sclerosis (ALS), Fragile X syndrome (FXS), Huntington's disease and spinal muscular atrophy (SMA).