cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Modeling and control of a bedside cable-driven lower-limb rehabilitation robot for bedridden individuals
Creators: name: Wang, Hongbo
name: Jian, Zhuo
name: Fang, Fanfu
name: Su, Hao
name: Li, Jicai
name: Wang, Daoyu
Publisher: name: Frontiers Media
Year: 2023

description: Individuals with acute neurological or limb-related disorders may be temporarily bedridden and unable to go to the physical therapy departments. The rehabilitation training of these patients in the ward can only be performed manually by therapists because the space in inpatient wards is limited. This paper proposes a bedside cable-driven lower-limb rehabilitation robot based on the sling exercise therapy theory. The robot can actively drive the hip and knee motions at the bedside using flexible cables linking the knee and ankle joints. A human–cable coupling controller was designed to improve the stability of the human–machine coupling system. The controller dynamically adjusts the impedance coefficient of the cable driving force based on the impedance identification of the human lower-limb joints, thus realizing the stable motion of the human body. The experiments with five participants showed that the cable-driven rehabilitation robot effectively improved the maximum flexion of the hip and knee joints, reaching 85° and 90°, respectively. The mean annulus width of the knee joint trajectory was reduced by 63.84%, and the mean oscillation of the ankle joint was decreased by 56.47%, which demonstrated that human joint impedance identification for cable-driven control can effectively stabilize the motion of the human–cable coupling system.
Optimal Scheduling in the Multiserver-job Model under Heavy Traffic
Creators: name: Grosof, Isaac
name: Scully, Ziv
name: Harchol-Balter, Mor
name: Scheller-Wolf, Alan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Performance (cs.PF)
subject: FOS: Computer and information sciences

description: Multiserver-job systems, where jobs require concurrent service at many servers, occur widely in practice. Essentially all of the theoretical work on multiserver-job systems focuses on maximizing utilization, with almost nothing known about mean response time. In simpler settings, such as various known-size single-server-job settings, minimizing mean response time is merely a matter of prioritizing small jobs. However, for the multiserver-job system, prioritizing small jobs is not enough, because we must also ensure servers are not unnecessarily left idle. Thus, minimizing mean response time requires prioritizing small jobs while simultaneously maximizing throughput. Our question is how to achieve these joint objectives. We devise the ServerFilling-SRPT scheduling policy, which is the first policy to minimize mean response time in the multiserver-job model in the heavy traffic limit. In addition to proving this heavy-traffic result, we present empirical evidence that ServerFilling-SRPT outperforms all existing scheduling policies for all loads, with improvements by orders of magnitude at higher loads. Because ServerFilling-SRPT requires knowing job sizes, we also define the ServerFilling-Gittins policy, which is optimal when sizes are unknown or partially known.
description: 32 pages, to appear in ACM SIGMETRICS 2023
The Proper Motion of the Galactic Center Pulsar Relative to Sagittarius A*
Creators: name: Bower, Geoffrey C.
name: Deller, Adam
name: Demorest, Paul
name: Brunthaler, Andreas
name: Falcke, Heino
name: Moscibrodzka, Monika
name: O'Leary, Ryan M.
name: Eatough, Ralph P.
name: Kramer, Michael
name: Lee, K. J.
name: Spitler, Laura
name: Desvignes, Gregory
name: Rushton, Anthony P.
name: Doeleman, Sheperd
name: Reid, Mark J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We measure the proper motion of the pulsar PSR J1745-2900 relative to the Galactic Center massive black hole, Sgr A*, using the Very Long Baseline Array (VLBA). The pulsar has a transverse velocity of 236 +/- 11 km s^-1 at position angle 22 +/- 2 deg East of North at a projected separation of 0.097 pc from Sgr A*. Given the unknown radial velocity, this transverse velocity measurement does not conclusively prove that the pulsar is bound to Sgr A*; however, the probability of chance alignment is very small. We do show that the velocity and position is consistent with a bound orbit originating in the clockwise disk of massive stars orbiting Sgr A* and a natal velocity kick of
description: Arxiv submission has been updated based on published erratum. ICRF positions reported for the magnetar are correct as reported in the original paper but relative positions are adjusted by (+18.36, -32.0) mas. Tables 2 and 4 and Figure 1 have been updated accordingly. Proper motion, acceleration, and core shift values are unaffected. There are no changes in the interpretation of the results
Additional file 2 of Electroencephalographic features in patients undergoing extracorporeal membrane oxygenation
Creators: name: Peluso, Lorenzo
name: Rechichi, Serena
name: Franchi, Federico
name: Pozzebon, Selene
name: Scolletta, Sabino
name: Brasseur, Alexandre
name: Legros, Benjamin
name: Jean-Louis Vincent
name: Creteur, Jacques
name: Gaspard, Nicolas
name: Taccone, Fabio Silvio
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2 Main characteristics of ECMO patients, according to EEG monitoring.
eqxydkyhu "kgjksa dk oxhZdj.k
Creators: name: Vafurk Dqekjh
Publisher: name: Zenodo
Year: 2022

description: सार eqxy dky esa 'kgjh vkcknh ds chp Li"V oxhZdj.k FkkA lcls etcwr fLFkfr 'kkld oxZ dh Fkh ftlesa lezkV vkSj mldk ifjokj] lkear vkSj cM+s vf/kdkjh 'kkfey FksA e/;e oxZ esa fuEu Lrj ds deZpkjh] O;kikjh vkSj dqN vU; O;olk;h oxZ Fks] tcfd lk/kkj.k Lrj ij f'kYidkj] dkjhxj vkSj lsod oxZ ds yksx FksA fofHkUu oxksZa dh fLFkfr esa ifjorZu dh lEHkkouk ges”kk cuh jgrh Fkh vkSj xzkeh.k leqnk; dh rqyuk esa 'kgjh lekt esa vf/kd xfr'khyrk FkhA1 eqxydkyhu Hkkjr eaas pkj vyx&vyx izdkj ds 'kgjh dsUnzksa dh igpku dh x;h gSA bl dky esa 'kgjksa dks muds egRo ds vk/kkj ij fofHkUu Jsf.k;ksa esa oxhZd`r fd;k tk ldrk FkkA oxhZdj.k dsoy ;g crkrk gS fd ml uxj esa og dk;Z izeq[k :i ls lEikfnr gksrk Fkk ijUrq vU; dk;Z Hkh uxj esa xkS.k :i ls gksrs FksA eqxydkyhu uxjksa ds eq[; izdkj fuEufyf[kr FksA
Additional file 1: of Item pre-knowledge true prevalence in clinical anatomy - application of gated item response theory model
Creators: name: Severo, Milton
name: Silva-Pereira, Fernanda
name: Ferreira, Maria
name: Monteiro, Magda
name: Pereira, Isabel
Publisher: name: Figshare
Year: 2019
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: WinBUGS DGM Model Commands. (DOCX 17 kb)
Accelerated nanoscale magnetic resonance imaging through phase multiplexing
Creators: name: Moores, B. A.
name: Eichler, A.
name: Tao, Y.
name: Takahashi, H.
name: Navaretti, P.
name: Degen, C. L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report a method for accelerated nanoscale nuclear magnetic resonance imaging by detecting several signals in parallel. Our technique relies on phase multiplexing, where the signals from different nuclear spin ensembles are encoded in the phase of an ultrasensitive magnetic detector. We demonstrate this technique by simultaneously acquiring statistically polarized spin signals from two different nuclear species (1H, 19F) and from up to six spatial locations in a nanowire test sample using a magnetic resonance force microscope. We obtain one-dimensional imaging resolution better than 5 nm, and subnanometer positional accuracy.
description: 14 pages, 6 figures
Regular subgraphs of uniform hypergraphs
Creators: name: Kim, Jaehoon
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: We prove that for every integer $r\geq 2$, an $n$-vertex $k$-uniform hypergraph $H$ containing no $r$-regular subgraphs has at most $(1+o(1)){{n-1}\choose{k-1}}$ edges if $k\geq r+1$ and $n$ is sufficiently large. Moreover, if $r\in\{3,4\}$, $r\mid k$ and $k,n$ are both sufficiently large, then the maximum number of edges in an $n$-vertex $k$-uniform hypergraph containing no $r$-regular subgraphs is exactly ${{n-1} \choose {k-1}}$, with equality only if all edges contain a specific vertex $v$. We also ask some related questions.
MOESM2 of Transgene stacking in potato using the GAANTRY system
Creators: name: McCue, Kent
name: Gardner, Ethan
name: Chan, Ronald
name: Thilmony, Roger
name: Thomson, James
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Plant Biology
subject: 60506 Virology

description: Additional file 2: Table S1. 10-stack cargo sequences in Donor plasmids.
Two photons on an atomic beam-splitter: nonlinear scattering and induced correlations
Creators: name: Roulet, Alexandre
name: Le, Huy Nguyen
name: Scarani, Valerio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Optical emitters strongly coupled to photons propagating in one-dimensional waveguides are a promising platform for optical quantum information processing. Here, we present a theoretical study of the scattering of two indistinguishable photons on a single two-level atom in a Hong-Ou-Mandel set-up. By computing the dynamics, we can describe the system at any time of the scattering event. This allows us to highlight the one-to-one correspondence between the saturation of the atom and the effective interaction induced between the photons. Furthermore, we discuss the integrability of the atomic beamsplitter and provide an intuitive picture for the correlations observed between the outgoing photons.
description: 13 pages, 11 figures, added a detailed study of the correlations induced by the atomic beam-splitter; accepted to Phys. Rev. A
Neural network models for sequence-based TCR and HLA association prediction
Creators: name: Sun, Wei
name: Liu, Si
name: Bradley, Philip
Publisher: name: Public Library of Science
Year: 2023

description: T cells rely on their T cell receptors (TCRs) to discern foreign antigens presented by human leukocyte antigen (HLA) proteins. The TCRs of an individual contain a record of this individual’s past immune activities, such as immune response to infections or vaccines. Mining the TCR data may recover useful information or biomarkers for immune related diseases or conditions. Some TCRs are observed only in the individuals with certain HLA alleles, and thus characterizing TCRs requires a thorough understanding of TCR-HLA associations. The extensive diversity of HLA alleles and the rareness of some HLA alleles present a formidable challenge for this task. Existing methods either treat HLA as a categorical variable or represent an HLA by its alphanumeric name, and have limited ability to generalize to the HLAs that are not seen in the training process. To address this challenge, we propose a neural network-based method named Deep learning Prediction of TCR-HLA association (DePTH) to predict TCR-HLA associations based on their amino acid sequences. We demonstrate that DePTH is capable of making reasonable predictions for TCR-HLA associations, even when neither the HLA nor the TCR have been included in the training dataset. Furthermore, we establish that DePTH can be used to quantify the functional similarities among HLA alleles, and that these HLA similarities are associated with the survival outcomes of cancer patients who received immune checkpoint blockade treatments.
Wege und Symbole des Heils
Creators: name: Dexinger, Ferdinand
name: Mesquita, Roque
name: Kassel, Maria
name: Scheuermann, Michael
name: Wostry, Franz
name: Schweizer, Rosa
name: Reck, Reinhold
name: Kuld, Lothar
Publisher: name: Diakonia
Year: 1970

description: Diakonia, Bd. 18 Nr. 4 (1987): Diakonia, Band 18, Heft 4
MOESM3 of Transgene stacking in potato using the GAANTRY system
Creators: name: McCue, Kent
name: Gardner, Ethan
name: Chan, Ronald
name: Thilmony, Roger
name: Thomson, James
Publisher: name: Figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Plant Biology

description: Additional file 3: Table S2. Primers and probes used for transgene detection.
Justifying mobility restrictions during the COVID-19 pandemic: a test in multilevel governance
Creators: name: Bélanger, Marie-Eve
name: Lavenex, Sandra
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: In public health crisis governance, effective communication has been shown to move people from awareness to compliance. This article examines the effectiveness of the communication strategy developed by stakeholders in the European multi-level governance during the COVID-19 pandemic. An original dataset of over 40,000 tweets from 65 actors in Switzerland, France, the UK, the EU and the UN is used to measure the timeliness, consistency and connectivity of tweets about mobility restrictions in the first phase of the pandemic. Analysis shows that the discourse surrounding mobility restrictions gradually becomes more politicised after an initial phase of high consistency and connectivity among actors. Additionally, low inter-level connectivity suggests a lack of coordination across governance levels, despite a strong consistency in the message. The study concludes that this pattern of communication could worsen the rising infodemic issue.
Time-Domain Separation of Optical Properties From Structural Transitions in Resonantly Bonded Materials
Creators: name: Waldecker, Lutz
name: Miller, Timothy A.
name: Rude, Miquel
name: Bertoni, Roman
name: Osmond, Johann
name: Pruneri, Valerio
name: Simpson, Robert
name: Ernstorfer, Ralph
name: Wall, Simon
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: The extreme electro-optical contrast between crystalline and amorphous states in phase change materials is routinely exploited in optical data storage and future applications include universal memories, flexible displays, reconfigurable optical circuits, and logic devices. Optical contrast is believed to arise due to a change in crystallinity. Here we show that the connection between optical properties and structure can be broken. Using a unique combination of single-shot femtosecond electron diffraction and optical spectroscopy, we simultaneously follow the lattice dynamics and dielectric function in the phase change material Ge2Sb2Te5 during an irreversible state transformation. The dielectric function changes by 30% within 100 femtoseconds due to a rapid depletion of electrons from resonantly-bonded states. This occurs without perturbing the crystallinity of the lattice, which heats with a 2 ps time constant. The optical changes are an order-of-magnitude larger than those achievable with silicon and present new routes to manipulate light on an ultrafast timescale without structural changes.
Lebertia Neuman 1880
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Lebertiidae
Lebertia

description: Genus Lebertia Neuman, 1880
Records not classified to species level from the study area: Uttaranchal—Kumar & Dobriyal (1992).
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 11, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
Additional file 1 of IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms
Creators: name: Valin, Alvaro
name: Rey, Manuel J. Del
name: Municio, Cristina
name: Usategui, Alicia
name: Romero, Marina
name: Fernández-Felipe, Jesús
name: Cañete, Juan D.
name: Blanco, Francisco J.
name: Ruano, Yolanda
name: Criado, Gabriel
name: Pablos, José L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Primer sequences used for quantitative real-time PCR analysis.
How citizens’ conceptions of democracy relate to positive and negative partisanship towards populist parties
Creators: name: Wegscheider, Carsten
name: Kaltwasser, Cristóbal Rovira
name: Van Hauwaert, Steven M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Although scholars emphasise the contentious relationship of populist forces to (liberal) democracy, less attention has been paid to whether this extends to those who support or oppose populist parties. This article utilises a public opinion dataset from ten Western European countries to analyse how citizens’ conceptions of democracy relate to the behavioural intention to vote for or against populist parties. The empirical analysis shows that positive and negative identification with populist parties is driven by different understandings of democracy: While individuals who are less inclined to liberal democracy but more to direct democracy and authoritarian forms of rule are more likely to sympathise with populist parties, the opposite understanding of democracy predicts opposition to both left-wing and right-wing populists. These findings demonstrate that citizens with positive and negative partisanship towards populist parties are divided in their interpretations about both the conceptual meaning and the normative functioning of democracy.
title: Generation of audiovisual immersive virtual environments to evaluate cognitive performance in classroom type scenarios
Creators: name: Fremerey, Stephan
name: Reimers, Carolin
name: Leist, Larissa
name: Spilski, Jan
name: Klatte, Maria
name: Fels, Janina
name: Raake, Alexander
Publisher: name: Deutsche Gesellschaft für Akustik e.V. (DEGA)
Year: 2021
Subjects: subject: 530

description: In the project ECoClass-VR, which is part of the AUDICTIVE priority programme, we investigate the suitability of audiovisual Immersive Virtual Environments (IVEs) for a “real-world” assessment of cognitive performance of adults and children in classroom-type environments under different visuospatial and acoustic conditions. Existing knowledge in this area comes predominantly from auditory experimental paradigms with typically simple acoustic replications. So far, only limited attention has been paid to visual processing, without considering relevant audiovisual aspects. In the project ECoClass-VR, it is planned to successively increase the realism of three existing psychological test paradigms that are first translated into audiovisual tasks and subsequently increased in terms of their realism with regard to cognitive tasks and IVEs. To do so, we use two different types of scene visualization: immersive 360° video, hence captured 360° video scenes and Computer Generated Imagery (CGI) based scenes generated by a software such as e.g. Unity. Within this paper, we present first results and explain how we captured and generated the corresponding IVEs. We describe the challenges as well as the technical solutions to achieve close-to-photorealism for two virtual representations of a classroom-type scene, and to enable the flexibility required for conducting the targeted cognitive performance tests.
description: Tagungsband - DAGA 2021: 47. Jahrestagung für Akustik : 15.-18. August 2021, Wien und Online : Tagungsband der DAGA 2021, p. 1336
Additional file 2 of IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms
Creators: name: Valin, Alvaro
name: Rey, Manuel J. Del
name: Municio, Cristina
name: Usategui, Alicia
name: Romero, Marina
name: Fernández-Felipe, Jesús
name: Cañete, Juan D.
name: Blanco, Francisco J.
name: Ruano, Yolanda
name: Criado, Gabriel
name: Pablos, José L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Figure S1. Kinetic patterns of gene expression in SF. SF were cultured in time-course experiments in the presence or absence of TNFα (10 ng/ml) (a), or IL6/sIL6R (50 ng/ml each) (b). An extended analysis of genes was measured by RT-qPCR, in addition to genes from Fig. 3 also depicted here. Data are mean ± SEM from three to six independent cultures.
Characterising the big pieces of Lipschitz graphs property using projections
Creators: name: Martikainen, Henri
name: Orponen, Tuomas
Publisher: name: arXiv
Year: 2014
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 28A75

description: We characterise the big pieces of Lipschitz graphs property in terms of projections. Roughly speaking, we prove that if a large subset of an $n$-Ahlfors-David regular set $E \subset \mathbb{R}^d$ has plenty of projections in $L^{2}$, then a large part of $E$ is contained in a single Lipschitz graph. This is closely related to a question of G. David and S. Semmes.
description: 19 pages, 4 figures. v3: Incorporated referee comments, to appear in JEMS
Partisanship and the Pandemic: How and Why Americans Followed Party Cues on COVID-19
Creators: name: Hetherington, Marc J.
name: Mehlhaff, Isaac D.
name: Tarillo, Matías C.
name: Vanegas, Ayelén
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: The United States underperformed its potential in responding to the COVID-19 pandemic. Using original survey data from April 2020 to March 2022, we show that political partisanship may have contributed to this inconsistent response by distinguishing elites and citizens who took the crisis seriously from those who did not. This division was not inevitable; when the crisis began, Democrats and Republicans differed little in their viewpoints and actions. However, partisans increasingly diverged when their preferred political leaders provided them with opposing cues. We outline developments in party politics over the last half-century that contributed to partisan division on COVID-19, most centrally an anti-expertise bias among Republicans. Accordingly, Republicans' support for mitigation measures, perception of severity of COVID-19, and support for vaccines gradually decreased after the initial outbreak. Partisan differences also showed up at the state level; Trump's vote share in 2016 was negatively associated with mask use and positively associated with COVID-19 infections. Diverging elite cues provided fertile ground for the partisan pandemic, underscoring the importance of political accountability, even in an era of polarization.
Status and performance of the AMoRE-I experiment on neutrinoless double beta decay
Creators: name: Kim, H. B.
name: Ha, D. H.
name: Jeon, E. J.
name: Jeon, J. A.
name: Jo, H. S.
name: Kang, C. S.
name: Kang, W. G.
name: Kim, H. S.
name: Kim, S. C.
name: Kim, S. G.
name: Kim, S. K.
name: Kim, S. R.
name: Kim, W. T.
name: Kim, Y. D.
name: Kim, Y. H.
name: Kwon, D. H.
name: Lee, E. S.
name: Lee, H. J.
name: Lee, H. S.
name: Lee, J. S.
name: Lee, M. H.
name: Lee, S. W.
name: Lee, Y. C.
name: Leonard, D. S.
name: Lim, H. S.
name: Mailyan, B.
name: Nyanda, P. B.
name: Oh, Y. M.
name: Sari, M. B.
name: Seo, J. W.
name: Seo, K. M.
name: Seo, S. H.
name: So, J. H.
name: Woo, K. R.
name: Yoon, Y. S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: AMoRE is an international project to search for the neutrinoless double beta decay of $^{100}$Mo using a detection technology consisting of magnetic microcalorimeters (MMCs) and molybdenum-based scintillating crystals. Data collection has begun for the current AMORE-I phase of the project, an upgrade from the previous pilot phase. AMoRE-I employs thirteen $^\mathrm{48depl.}$Ca$^{100}$MoO$_4$ crystals and five Li$_2$$^{100}$MoO$_4$ crystals for a total crystal mass of 6.2 kg. Each detector module contains a scintillating crystal with two MMC channels for heat and light detection. We report the present status of the experiment and the performance of the detector modules.
description: 8 pages, 4 figures, published in Journal of Low Temperature Physics (2022)
Additional file 4 of IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms
Creators: name: Valin, Alvaro
name: Rey, Manuel J. Del
name: Municio, Cristina
name: Usategui, Alicia
name: Romero, Marina
name: Fernández-Felipe, Jesús
name: Cañete, Juan D.
name: Blanco, Francisco J.
name: Ruano, Yolanda
name: Criado, Gabriel
name: Pablos, José L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4: Figure S3. Scheme of the cooperative role of TNFα and IL6/sIL6R in regulating the inflammatory response in SF. (a) TNFα induces a strong inflammatory response in SF during RA, mediating the infiltration of monocytic and leukocytic cells as well as neutrophils, the expression of matrix degradative metalloproteases, but also potentially activating mechanisms to control the inflammatory program. Part of these effects are mediated through activation of JAK/STAT signaling pathways. (b) In this TNFα- inflammatory context, IL6/sIL6R would be playing a major role in the transition to sustained inflammation, enhancing leukocyte infiltration and joint destruction.
Oleic Acid Exhibits Anti-Proliferative and Anti-Invasive Activities via the PTEN/AKT/mTOR Pathway in Endometrial Cancer
Creators: name: Newton, Meredith A.
name: Shen, Xiaochang
name: John, Catherine
name: Deng, Boer
name: Hao, Tianran
name: Suo, Hongyan
name: Zhou, Chunxiao
name: Zhang, Xin
name: Kong, Weimin
name: Zhao, Ziyi
name: Burkett, Wesley C.
name: Bae-Jump, Victoria L.
name: Fan, Yali
name: Sun, Wenchuan
Publisher: name: MDPI
Year: 2023

description: Reprogramming of fatty acid metabolism promotes cell growth and metastasis through a variety of processes that stimulate signaling molecules, energy storage, and membrane biosynthesis in endometrial cancer. Oleic acid is one of the most important monounsaturated fatty acids in the human body, which appears to have both pro- and anti-tumorigenic activities in various pre-clinical models. In this study, we evaluated the potential anti-tumor effects of oleic acid in endometrial cancer cells and the LKB1fl/flp53fl/fl mouse model of endometrial cancer. Oleic acid increased lipogenesis, inhibited cell proliferation, caused cell cycle G1 arrest, induced cellular stress and apoptosis, and suppressed invasion in endometrial cancer cells. Targeting of diacylglycerol acyltransferases 1 and 2 effectively increased the cytotoxicity of oleic acid. Moreover, oleic acid significantly increased the expression of wild-type PTEN, and knockdown of PTEN by shRNA partially reversed the anti-proliferative and anti-invasive effects of oleic acid. Inhibition of the AKT/mTOR pathway by ipatasertib effectively increased the anti-tumor activity of oleic acid in endometrial cancer cells. Oleic acid treatment (10 mg/kg, daily, oral) for four weeks significantly inhibited tumor growth by 52.1% in the LKB1fl/flp53fl/fl mice. Our findings demonstrated that oleic acid exhibited anti-tumorigenic activities, dependent on the PTEN/AKT/mTOR signaling pathway, in endometrial cancer.
Moduli Spaces of Lumps on Real Projective Space
Creators: name: Krusch, Steffen
name: Muhamed, Abera A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Harmonic maps that minimise the Dirichlet energy in their homotopy classes are known as lumps. Lump solutions on real projective space are explicitly given by rational maps subject to a certain symmetry requirement. This has consequences for the behaviour of lumps and their symmetries. An interesting feature is that the moduli space of charge three lumps is a $7$-dimensional manifold of cohomogeneity one which can be described as a one-parameter family of symmetry orbits of $D_2$ symmetric maps. In this paper, we discuss the charge three moduli spaces of lumps from two perspectives: discrete symmetries of lumps and the Riemann-Hurwitz formula. We then calculate the metric and find explicit formulas for various geometric quantities. We also discuss the implications for lump decay.
description: 25 pages, 3 figures, this version is accepted for publication in JMP
Identification and Molecular Dynamic Simulation of Flavonoids from Mediterranean species of Oregano against the Zika NS2B-NS3 Protease
Creators: name: Ghosh, Anushikha
name: Sanyal, Arka
name: Sharma, Sameer
Publisher: name: arXiv
Year: 2022
Subjects: subject: Biomolecules (q-bio.BM)
subject: FOS: Biological sciences

description: The Zika virus, is an emerging infectious disease causing severe complications such as microcephaly in infants and Guillain Barre syndrome in adults. There is no licensed vaccination or approved medicine to treat ZIKV infection. Therefore, extensive research is being carried out to find compounds that can be used effectively as therapeutic molecules to treat ZIKV infection. Oregano, a commonly found herb in the Mediterranean region, has been used predominantly for culinary purposes. The fact that the members of the Origanum species are a storehouse of various bioactive compounds gives us a solid reason to study compounds extracted from it for therapeutic purposes. In this study, were retrieved 20 Flavonoids found in various Origanum species belonging to the Mediterranean region from the PubChem database and pharmacological analysis using SwissADME and Molecular docking using AutoDock Vina 4.0. were carried out against the NS2B NS3 protease since it serves as an effective drug target owing to its role in viral replication and immune evasion within the host. The best hit compounds were subjected to MD simulation at 100 ns using Desmond Schrodinger to analyze the molecule's stability. We observed Cirsiliol as the best hit compound against the NS2B NS3 complex with a binding affinity of -8.5 kcal per mol. It also showed good stability during MD simulation. We recommend the use of Cirsiliol for in vitro and in vivo studies for further investigation concerning the ZIKA virus.
description: 24 Pages, 12 Figures
Additional file 3 of IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms
Creators: name: Valin, Alvaro
name: Rey, Manuel J. Del
name: Municio, Cristina
name: Usategui, Alicia
name: Romero, Marina
name: Fernández-Felipe, Jesús
name: Cañete, Juan D.
name: Blanco, Francisco J.
name: Ruano, Yolanda
name: Criado, Gabriel
name: Pablos, José L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3: Figure S2. Effect of cycloheximide on TNFα- and IL6/sIL6R-induced genes. TNFα-induced (10 ng/ml) (a) and, IL6/sIL6R-induced (50 ng/ml each) (b) mRNA expression for 24 h in the presence and absence of cycloheximide (CHX) (10 μM). Mean ± SEM from three to six independent SF cultures.
Inclusive candidate selection and corruption: evidence from Spanish regions
Creators: name: Charron, Nicholas
name: Schwenk, Jana
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: High corruption perceptions among voters have been shown to have dire consequences for political participation, trust in institutions and ability to solve collective action problems. Research on corruption focussed on macro- and micro-level explanations to explain persistent corruption in developed countries. This article adds a new meso-level variable to the picture: party primaries. While until recently selection of candidates was the privilege of narrow party elites, many Western European parties have introduced primaries to select candidates for public offices. This study posits that this attempt at increasing intraparty democracy has negative consequences regarding corruption perceptions and suggests three mechanisms through which primaries increase corruption perceptions among supporters of parties that use them. First, primaries can be perceived as a means of ‘window-dressing’, second, primaries can suffer from vote buying, and third, candidates in primaries have incentives to campaign on anti-elitism to distinguish themselves from party elite candidates, increasing corruption salience. The theoretical argument is tested using a novel dataset on primaries in Spanish regions and corruption perceptions in a difference-in-difference design. The results support the hypothesis that primaries increase corruption perceptions among supporters of parties that use them and hint that this result is driven by the process of competitive primaries rather than a restriction of competition.
Current Landscape of Mesenchymal Stem Cell Therapy in COVID Induced Acute Respiratory Distress Syndrome
Creators: name: Chanda, Adrita
name: Aich, Adrija
name: Sanyal, Arka
name: Chandra, Anantika
name: Goswami, Saumyadeep
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cell Behavior (q-bio.CB)
subject: FOS: Biological sciences

description: The severe acute respiratory syndrome coronavirus 2 outbreak in Chinas Hubei area in late 2019 has now created a global pandemic that has spread to over 150 countries. In most people, COVID 19 is a respiratory infection that produces fever, cough, and shortness of breath. Patients with severe COVID 19 may develop ARDS. MSCs can come from a number of places, such as bone marrow, umbilical cord, and adipose tissue. Because of their easy accessibility and low immunogenicity, MSCs were often used in animal and clinical research. In recent studies, MSCs have been shown to decrease inflammation, enhance lung permeability, improve microbial and alveolar fluid clearance, and accelerate lung epithelial and endothelial repair. Furthermore, MSC-based therapy has shown promising outcomes in preclinical studies and phase 1 clinical trials in sepsis and ARDS. In this paper, we posit the therapeutic strategies using MSC and dissect how and why MSC therapy is a potential treatment option for COVID 19 induced ARDS. We cite numerous promising clinical trials, elucidate the potential advantages of MSC therapy for COVID 19 ARDS patients, examine the detriments of this therapeutic strategy and suggest possibilities of subsequent research.
description: 14 Pages, 6 Figures
Full faithfulness for overconvergent F-de Rham-Witt connections
Creators: name: Ertl, Veronika
Publisher: name: arXiv
Year: 2014
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 14F20, 14F30

description: Let X be a smooth variety over a perfect field of characteristic p>0. In this small note we define overconvergent F-de Rham-Witt connections as an analogue for F-crystals over proper schemes. We prove that the forgetful functor from the category of overconvergent F-de Rham-Witt connections to the category of convergent F-de Rham-Witt connections is fully faithful. The argument is an analogue of a discussion by Kedlaya on full faithfulness of overconvergent F-isocrystals.}
description: 6 pages. Key Words: Witt vectors, overconvergent F-crystals, de Rham-Witt connections, Frobenius, slope
The Development of Processed Coconut Products by Bungasire Savings Community Enterprise, Tha Klong Village, Pattani Province
Creators: name: Nipatimah Hayehama
Publisher: name: Faculty of Liberal Arts, Prince of Songkla University
Year: 2023
Subjects: coconut products
packaging development
community enterprise

description: Journal of Liberal Arts, Prince of Songkla University, 15, 2, 265454, pp. 1-15
Perceived vulnerability to infectious disease and perceived harmfulness are as predictive of citizen response to COVID-19 as partisanship
Creators: name: Cassario A.
Publisher: name: Cambridge University Press
Year: 2023

description: Partisans have biased perceptions of objective conditions. At first glance, the COVID-19 pandemic would appear to be an example of this phenomenon. Noting that most citizens have consistently agreed about the pandemic, I argue that we have overlooked pre-political factors that are as influential as partisanship in shaping citizens' responses to the pandemic. I identify one such construct in perceived vulnerability to infectious disease (PVD). In one cross-sectional study and one panel study, I find that the influence of PVD on citizens' perceptions of COVID-19 equals that of partisanship. I also find that PVD can moderate the influence of partisanship on perceptions of harmfulness, nearly erasing the impact of being a Republican on perceiving COVID-19 as a threat. When led by PVD as well as partisanship to accurately perceive harm, citizens, including Republicans, attribute more responsibility to former president Donald Trump for his failed handling of the crisis. © The Author(s), 2023. Published by Cambridge University Press on behalf of the Association for Politics and the Life Sciences.
Additional file 1 of Screening for sickle cell disease in newborns: a systematic review
Creators: name: Runkel, Britta
name: Klüppelholz, Birgit
name: Rummer, Anne
name: Sieben, Wiebke
name: Lampert, Ulrike
name: Bollig, Claudia
name: Markes, Martina
name: Paschen, Ulrike
name: Angelescu, Konstanze
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1. PRISMA checklist.
It’s a hoax! The mediating factors of populist climate policy opposition
Creators: name: Meijers, Maurits J.
name: van Drunen, Yaël
name: Jacobs, Kristof
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mental Health

description: Many citizens are sceptical of policies implemented to mitigate climate change. Existing research shows that citizens’ populist beliefs are significant determinants of climate scepticism. However, little is known about the underlying factors driving populist opposition to climate policies. To address this gap in the literature, this study develops structural equation models with new ideological measures using a high-quality probability sample of Dutch citizens (2019). The findings show that the relationship between populist attitudes and climate policy opposition is mediated through two anti-elite dispositions: the idea that climate science is unreliable and the belief that politicians exploit climate change for political gain. This relationship holds for left- and right-wing individuals alike. Moreover, a replication of a recent study shows that these findings hold alongside mechanisms rooted in institutional trust. These findings provide important evidence that populists’ opposition to climate policy is principally rooted in distrust in political and scientific elites.
Additional file 5: of Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
Creators: name: Castro, Andrea
name: Kivilcim Ozturk
name: Pyke, Rachel
name: Xian, Su
name: Zanetti, Maurizio
name: Carter, Hannah
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Figure S5. Mutation burden in CCLE, related to Fig. 3. Boxplots showing the total number of nonsynonymous mutations for CCLE cell lines who acquired a B2M or HLA versus cell lines that did not acquire any B2M or HLA mutation. Sample sizes for each group are written under their name. (PDF 345 kb)
Additional file 6: of Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
Creators: name: Castro, Andrea
name: Kivilcim Ozturk
name: Pyke, Rachel
name: Xian, Su
name: Zanetti, Maurizio
name: Carter, Hannah
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Figure S6. Total number of binding neoantigens to patient HLA alleles, related to Fig. 4. (A) Distribution of median total counts of binding neoantigens at different PHBR-I score cutoffs for MSS patients. (B) Boxplots comparing the number of neoantigens in MSS patients with no B2M or HLA mutation (teal) versus MSS patients with a B2M mutation (yellow) or an HLA mutation (purple). A PHBR-I score cutoff of 2 was used to designate a binding neoantigen for this comparison. (PDF 419 kb)
Postural Control Measurements to Predict Future Motor Impairment in Preterm Infants: A Systematic Review
Creators: name: McCarty, Dana B.
name: LeBlond, Kristen D.
name: Bosserman, Jennifer
name: Kelkar, Sonia
name: Cassidy, Jessica
Publisher: name: MDPI
Year: 2023

description: Preterm infants are more likely to demonstrate developmental delays than fullterm infants. Postural measurement tools may be effective in measuring the center of pressure (COP) and asymmetry, as well as predicting future motor impairment. The objective of this systematic review was to evaluate existing evidence regarding use of pressure mats or force plates for measuring COP and asymmetry in preterm infants, to determine how measures differ between preterm and fullterm infants and if these tools appropriately predict future motor impairment. The consulted databases included PubMed, Embase, Scopus, and CINAHL. The quality of the literature and the risk of bias were assessed utilizing the ROB2: revised Cochrane risk-of bias tool. Nine manuscripts met the criteria for review. The postural control tools included were FSA UltraThin seat mat, Conformat Pressure-Sensitive mat, Play and Neuro-Developmental Assessment, and standard force plates. Studies demonstrated that all tools were capable of COP assessment in preterm infants and support the association between the observation of reduced postural complexity prior to the observation of midline head control as an indicator of future motor delay. Postural measurement tools provide quick and objective measures of postural control and asymmetry. Based on the degree of impairment, these tools may provide an alternative to standardized assessments that may be taxing to the preterm infant, inaccessible to therapists, or not sensitive enough to capture motor delays.
Strong convergence for split-step methods in stochastic jump kinetics
Creators: name: Engblom, Stefan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65C40, 60H35, 60J28, 92C45

description: Mesoscopic models in the reaction-diffusion framework have gained recognition as a viable approach to describing chemical processes in cell biology. The resulting computational problem is a continuous-time Markov chain on a discrete and typically very large state space. Due to the many temporal and spatial scales involved many different types of computationally more effective multiscale models have been proposed, typically coupling different types of descriptions within the Markov chain framework. In this work we look at the strong convergence properties of the basic first order Strang, or Lie-Trotter, split-step method, which is formed by decoupling the dynamics in finite time-steps. Thanks to its simplicity and flexibility, this approach has been tried in many different combinations. We develop explicit sufficient conditions for path-wise well-posedness and convergence of the method, including error estimates, and we illustrate our findings with numerical examples. In doing so, we also suggest a certain partition of unity representation for the split-step method, which in turn implies a concrete simulation algorithm under which trajectories may be compared in a path-wise sense.