cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Charges and fields in a current-carrying wire
Creators: name: Redzic, Dragan V.
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Physics (physics.gen-ph)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: Charges and fields in a straight, infinite, cylindrical wire carrying a steady current are determined in the rest frames of ions and electrons, starting from the standard assumption that the net charge per unit length is zero in the lattice frame and taking into account a self-induced pinch effect. The analysis presented illustrates the mutual consistency of classical electromagnetism and Special Relativity. Some consequences of the assumption that the net charge per unit length is zero in the electrons frame are also briefly discussed.
Popular support for the no-concessions policy in terrorist hostage takings
Creators: name: Mertes, Marc
name: Böhm, Robert
name: Hüffmeier, Joachim
Publisher: name: TU Dortmund
Year: 2024
Subjects: subject: terrorist hostage-takings
subject: no-concessions policy
subject: moral dilemma
subject: information processing
subject: 150
subject: Geiselnahme
subject: Terrorismus
subject: Bevölkerung
subject: Politik

description: Governmental responses to the frequently occurring terrorist hostage-takings, in which authorities must weigh the lives of the hostages against the lives of potential future victims, depend on popular support for governmental policy. Yet, little is known about how people form their judgement of governmental policies in this moral dilemma. We argue that people typically have imperfect information and their policy support for concessions can be substantially altered by changing the information they possess about different consequences. Across three studies (overall N = 1,547) employing both qualitative and quantitative methods, we found that (a) support for concessions is negatively linked to age and political conservatism, (b) most people either focus only on one aspect or have an imperfect representation of this moral dilemma when thinking about their support for concessions, (c) providing information on the benefits of concessions increases support for concessions, and (d) support for concessions increases when the benefits outweigh the costs and when a salient moral norm prescribes concessions. The potential implications for policymakers are discussed.
description: Collabra: Psychology; 10(1)
A Checkpoint that Links mRNA Export Competence with Replication Stress and Genomic Integrity
Creators: name: WILLIAMS, TOBIAS DANA
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 321101
subject: Cancer cell biology

description: Cancer has classically been regarded as a disease of gene expression, whereby information from DNA, namely RNA, is used to synthesise a functional gene product such as protein. Recent evidence has highlighted that proteins involved in transport of RNA are systematically altered in a variety of cancers but the picture is far from complete. I have discovered a completely new RNA checkpoint that regulates the transport of damaged RNA. Characterisation of this novel pathway will provide new information on how cells respond to stress and how this contributes to the development and progression of cancer.
Teachers’ prosociality and well-being at work: the mediating role of teacher engagement in family–school partnerships
Creators: name: Yotyodying, Sittipan
name: Dettmers, Swantje
name: Jonkmann, Kathrin
Publisher: name: TU Dortmund
Year: 2023
Subjects: subject: Prosociality
subject: Well-being at work
subject: Family-school partnerships
subject: 370
subject: Lehrer
subject: Lehrerin
subject: Wohlbefinden
subject: Elternarbeit

description: Past research provided strong evidence that positive family–school partnerships were not only beneficial for students’ school success, but they also helped to promote parental involvement in schooling. However, relatively little is known about teachers’ reasons for becoming engaged in family–school partnerships and the benefits of their engagement. In fact, the role of teachers in family–school partnerships requires prosocial actions (e.g., helping, sharing, feeling empathy). As guided by self-determination theory, previous studies suggest that prosocial-oriented persons tend to take prosocial actions and these actions tend to promote a social connection, thereby promoting well-being. To the best of our knowledge, this assumption has not been applied to research on family–school partnerships yet. The aim of this study was to examine whether teachers’ prosociality would be associated with their well-being at work (i.e., job satisfaction, work-related self-esteem) and whether this connection would be mediated by teacher engagement in family–school partnerships. Using the framework of the Vodafone Foundation Germany, we focused on two important aspects of teacher engagement: effective communication and educational cooperation. A total of 190 teachers (72% females; mean age: 44.78 years) participated in an online-survey. In line with SDT, teachers’ prosociality was associated with greater well-being at work even after controlling for teachers’ background (age, gender, experience, school track). As expected, this connection was partially mediated by teacher engagement in family–school partnerships. The results and implications of the present study are discussed.
description: Social psychology of education; 27(4)
Ordered Array of Single Adatoms with Remarkable Thermal Stability: Au/Fe3O4(001)
Creators: name: Novotný, Zbyněk
name: Argentero, Giacomo
name: Wang, Zhiming
name: Schmid, Michael
name: Diebold, Ulrike
name: Parkinson, Gareth S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Gold deposited on the Fe$_3$O$_4$(001) surface at room temperature was studied using Scanning Tunneling Microscopy (STM) and X-ray photoelectron spectroscopy (XPS). This surface forms a ($\sqrt2 \times \sqrt2$)R45$^{\circ}$ reconstruction, where pairs of Fe and neighboring O ions are slightly displaced laterally producing undulating rows with `narrow' and `wide' hollow sites. At low coverages, single Au adatoms adsorb exclusively at the narrow sites, with no significant sintering up to annealing temperatures of 400 $^{\circ}$C. We propose the strong site preference to be related to charge and orbital ordering within the first subsurface layer of Fe$_3$O$_4$(001)-($\sqrt2 \times \sqrt2$)R45$^{\circ}$. Due to its high thermal stability, this could prove an ideal model system for probing the chemical reactivity of single atomic species.
description: 5 pages, 4 figures. arXiv admin note: substantial text overlap with arXiv:1203.5850
Coupled Chemistry-Emission Model for Atomic Oxygen Green and Red-doublet Emissions in Comet C/1996 B2 Hyakutake
Creators: name: Bhardwaj, Anil
name: Raghuram, Susarla
Publisher: name: arXiv
Year: 2012
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: The green (5577 Å) and red-doublet (6300, 6364 Å) lines are prompt emissions of metastable oxygen atoms in the $^1$S and $^1$D states, respectively, that have been observed in several comets. The value of intensity ratio of green to red-doublet (G/R ratio) of 0.1 has been used as a benchmark to identify the parent molecule of oxygen lines as H$_2$O. A coupled chemistry-emission model is developed to study the production and loss mechanisms of O($^1$S) and O($^1$D) atoms and the generation of red and green lines in the coma of C/1996 B2 Hyakutake. The G/R ratio depends not only on photochemistry, but also on the projected area observed for cometary coma, which is a function of the dimension of the slit used and geocentric distance of the comet. Calculations show that the contribution of photodissociation of H$_2$O to the green (red) line emission is 30 to 70% (60 to 90%), while CO$_2$ and CO are the next potential sources contributing 25 to 50% ($
Development and differentiation of hyperstable consensus monobodies based on the type 3 fibronectin domain
Creators: name: CHANDLER, PETER GEOFFREY
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 320402
subject: Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)
classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310112
subject: Structural biology (incl. macromolecular modelling)
classificationCode: 320506
subject: Medical biochemistry - proteins and peptides (incl. medical proteomics)

description: Monobodies based on the type 3 fibronectin (FN3) domain are designed to overcome limitations of the antibody binding scaffold, being more simple and more amenable to the rigours of drug development. This thesis focuses on the development of FN3Con, a hyperstable consensus FN3 monobody. Through grafting of binding loops from monobodies of median stability, this work produced two FN3Con constructs with affinity to clinical targets and a shelf life of over 2 years at room temperature. The thesis then investigates methods to meaningfully differentiate monobodies from the antibody scaffold through buffer excipients, chemical conjugation and integration of native fibronectin characteristics.
On the pros and cons of red photons for greenhouse tomato production: increasing the percentage of red photons improves LED efficacy but plant responses are cultivar-specific
Creators: name: Kusuma, Paul
name: Ouzounis, Theoharis
name: Hawley, David
name: Kerstens, Tijmen
name: Marcelis, Leo F.M.
name: Heuvelink, Ep
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Supplemental lighting is necessary for winter greenhouse tomato production, and optimised spectra must consider both yield and energy use. In a 20-week winter greenhouse experiment, two common commercial tomato cultivars – ‘Merlice’ and ‘Brioso’ – were grown under four LED spectra with 38%, 63%, 81%, and 95% red photons. As the percentage of red photons increased, the blue and green percentages decreased (not at the same ratio). Stem length, specific leaf area, and dry mass partitioning were not significantly affected by spectra in either cultivar, but increasing the red percentage from 38% to 95% decreased harvested fruit fresh mass by 13%, total plant dry mass by 7.1%, and fruit dry mass by 9.5% in ‘Merlice’. There were no significant differences in these parameters for ‘Brioso’. The yield kWh−1 increased with increasing percent red in both cultivars because LED fixtures with higher fractions of photons from 660 nm red LEDs have higher photon efficacies (µmol J−1). The efficacies of the lamps in this study were estimated to range from 2.6 to 3.6 µmol J−1. Growers must consider tradeoffs that can occur between yield and efficacy in some cultivars, and how these factors apply to their situation, when choosing the spectrum for their greenhouse.
Characterization of Novel Oncogenes in Triple Negative Breast Cancer
Creators: name: YANG, XUE
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 321199
subject: Oncology and carcinogenesis not elsewhere classified
classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology

description: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer, which currently has a paucity of targeted treatments. PEAK1 and NRBP1 are pseudokinases implicated in human cancers, their TNBC-related functions and mechanisms were explored during my PhD. I identified that CAMK2, an interactor of PEAK1, is required for PEAK1-promoted TNBC development. Pharmacological inhibition of CAMK2 blocks oncogenic roles of PEAK1. My findings support the notion that PEAK1 in combination with CAMK2 could be used as companion biomarkers to select patients for anti-CAMK2 treatment. My work also established pro-tumorigenic functions of NRBP1 in TNBC, highlighting NRBP1 as a candidate molecular target, and its regulating signalling pathways could be developed into therapeutic options.
The AMBRE Project: Stellar parameterisation of the ESO:FEROS archived spectra
Creators: name: Worley, C. C.
name: de Laverny, P.
name: Recio-Blanco, A.
name: Hill, V.
name: Bijaoui, A.
name: Ordenovic, C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The AMBRE Project is a collaboration between the European Southern Observatory (ESO) and the Observatoire de la Cote d'Azur (OCA) that has been established in order to carry out the determination of stellar atmospheric parameters for the archived spectra of four ESO spectrographs. The analysis of the FEROS archived spectra for their stellar parameters (effective temperatures, surface gravities, global metallicities, alpha element to iron ratios and radial velocities) has been completed in the first phase of the AMBRE Project. From the complete ESO:FEROS archive dataset that was received, a total of 21551 scientific spectra have been identified, covering the period 2005 to 2010. These spectra correspond to ~6285 stars. The determination of the stellar parameters was carried out using the stellar parameterisation algorithm, MATISSE (MATrix Inversion for Spectral SynthEsis), which has been developed at OCA to be used in the analysis of large scale spectroscopic studies in galactic archaeology. An analysis pipeline has been constructed that integrates spectral reduction and radial velocity correction procedures with MATISSE in order to automatically determine the stellar parameters of the FEROS spectra. Stellar atmospheric parameters (Teff, log g, [M/H] and [alpha/Fe]) were determined for 6508 (30.2%) of the FEROS archived spectra (~3087 stars). Radial velocities were determined for 11963 (56%) of the archived spectra. 2370 (11%) spectra could not be analysed within the pipeline. 12673 spectra (58.8%) were analysed in the pipeline but their parameters were discarded based on quality criteria and error analysis determined within the automated process. The majority of these rejected spectra were found to have broad spectral features indicating that they may be hot and/or fast rotating stars, which are not considered within the adopted reference synthetic spectra grid of FGKM stars.
description: 28 pages, 28 figures, 9 tables
D4.4 SHERPA online repository development documentation and user manual
Creators: name: Espejo Garcia, Borja
name: Fountas, Spyros
name: Mouseti, Sofia
name: Panoutsopoulos, Hercules
Publisher: name: Zenodo
Year: 2020

description: The work documented in this deliverable relates to the development and deployment of the initial version of the SHERPA online repository. The purpose of the SHERPA repository is to enable a broad range of potential users to access information and content pointing to: (i) rural topics addressed and investigated in the context of the Multi-Actor Platforms operating in SHERPA (at both the national/regional and EU levels); (ii) the research projects associated with each rural topic and the outputs produced by them; (iii) results obtained from text-mining and natural Language Processing methods applied to text-based project outputs; and (iv) the papers produced in the SHERPA project (e.g. the SHERPA Discussion and Position papers).
Ion acceleration in non-relativistic astrophysical shocks
Creators: name: Gargaté, L.
name: Spitkovsky, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We explore the physics of shock evolution and particle acceleration in non-relativistic collisionless shocks using multidimensional hybrid simulations. We analyze a wide range of physical parameters relevant to the acceleration of cosmic rays (CRs) in astrophysical non-relativistic shock scenarios, such as in supernova remnant (SNR) shocks. We explore the evolution of the shock structure and particle acceleration efficiency as a function of Alfvénic Mach number and magnetic field inclination angle $θ$. We show that there are fundamental differences between high and low Mach number shocks in terms of the electromagnetic turbulence generated in the pre-shock zone and downstream; dominant modes are resonant with the streaming CRs in the low Mach number regime, while both resonant and non-resonant modes are present for high Mach numbers. Energetic power law tails for ions in the downstream plasma can account for up to 15% of the incoming upstream flow energy, distributed over $\sim5%$ of the particles in a power law with slope $-2\pm0.2$ in energy. The energy conversion efficiency (for CRs) peaks at $θ=15^\circ$ to $30^\circ$ and $M_A=6$, and decreases for higher Mach numbers, down to $\sim2%$ for $M_A=31$. Accelerated particles are produced by Diffusive Shock Acceleration (DSA) and by Shock Drift Acceleration (SDA) mechanisms, with the SDA contribution to the overall energy gain increasing with magnetic inclination. We also present a direct comparison between hybrid and fully kinetic particle-in-cell results at early times; the agreement between the two models justifies the use of hybrid simulations for longer-term shock evolution. In SNR shocks, particle acceleration will be significant for low Mach number quasi-parallel flows ($M_A < 30$, $θ< 45$). This finding underscores the need for effective magnetic amplification mechanism in SNR shocks.
Uniform Patterns of Fe Vacancy Ordering in the Kx(Fe,Co)2-ySe2 Superconductors
Creators: name: Kazakov, Sergey M.
name: Abakumov, Artem M.
name: González, Santiago
name: Perez-Mato, Juan Manuel
name: Ovchinnikov, Alexander V.
name: Roslova, Maria V.
name: Boltalin, Alexander I.
name: Morozov, Igor V.
name: Antipov, Evgeny V.
name: Van Tendeloo, Gustaaf
Publisher: name: arXiv
Year: 2011
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The Fe-vacancy ordering patterns in the superconducting KxFe2-ySe2 and non-superconducting Kx(Fe,Co)2-ySe2 samples have been investigated by electron diffraction and high angle annular dark field scanning transmission electron microscopy. The Fe-vacancy ordering occurs in the ab plane of the parent ThCr2Si2-type structure, demonstrating two types of patterns. The superstructure I retains the tetragonal symmetry and can be described with the aI = bI = as{\surd}5 (as is the unit cell parameter of the parent ThCr2Si2-type structure) supercell and I4/m space group. The superstructure II reduces the symmetry to orthorhombic with the aII = as{\surd}2, bII = 2as{\surd}2 supercell and the Ibam space group. This type of superstructure is observed for the first time in KxFe2-ySe2. The Fe-vacancy ordering is inhomogeneous: the disordered areas interleave with the superstructures I and II in the same crystallite. The observed superstructures represent the compositionally-dependent uniform ordering patterns of two species (the Fe atoms and vacancies) on a square lattice. More complex uniform ordered configurations, including compositional stripes, can be predicted for different chemical compositions of the KxFe2-ySe2 (0 < y < 0.5) solid solutions.
description: This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Chemistry of Materials (copyright American Chemical Society) after peer review. To access the final edited and published work see Chem. Mater. 2011, 23, 4311-4316. 17 pages, 8 figures
title: Resisting Modernism
Creators: name: Yang, Simon
Publisher: name: PORTALES: The Undergraduate Journal of the Department of Latin American and Iberian Cultures
Year: 2021

description: Following the lead of modernist architects such as Lúcio Costa and Oscar Niemeyer, postwar Brazil aimed to devote considerable resources to the development of a newly homogenized national identity through central planning. Despite this widespread impulse towards modernization, the continued prominence of the favelas even to this day undermines the ideals of modernist urban renewal. The supposed “backwardness” of the favelas challenges the success narrative of Brazil’s modernist program. The paradoxical growth of the favelas in the midst of state-sponsored modernist renewal illustrates not only the failure of the modernist program, but also the internal contradictions within modernism itself. The failure to eradicate the favelas has instead resulted in the emergence of a heterogeneous national identity, contrary to the national goal of seamless modernizing integration. In recent decades, as the favelas resisted national efforts towards eradication, the culture of the favelas has become only more complex. Indeed, the rise of vernacular culture within the favelas has paradoxically allowed Brazil to promote itself internationally under the sign of heterogeneity and cultural difference. Contrary to the modernist ideal of abandoning all vernacular culture, the heterogeneous national identity derived from Brazil’s favelas boasts an organic amalgam of historical cultures. Ranging across music, religion, and architecture, this “heterogeneity” takes influence from diverse cultural spheres within Brazil. Resisting modernism’s characteristic emphasis on integrated, hierarchical planning, the heterogeneous favela culture instead proceeds through gradual incorporation and reinterpretation, effecting an organic novelty.
description: PORTALES: The Undergraduate Journal of the Department of Latin American and Iberian Cultures, Vol. 5 No. 1 (2021): Portales: The LAIC Undergraduate Journal
NEMIS MASALLARIDAGI PEDAGOGIK QARASHLAR VA DIDAKTIK G'OYALAR
Creators: name: G'aniyev, Fazliddin
Publisher: name: Zenodo
Year: 2023

description: Ushbu maqolada K.Gellertning masalchilik ijodi fransuz Filipp Detush (16801754) va Per de Laxosset (16801754) tomonidan yaratilgan teatr janri "larmoyante komediyasi". "comedie larmoyante", 1692-1754) bilan uzviy bogʻliq. K.Gellertning "Beshiktebratar" ("Gottesanbeterin") va "Kasal xotin" ("Die kranke Frau") masallari  va "Yoqimtoy opa-singillar" ("Die Zärtlichen Schwester") komediyasida K.Gellert masal orqali axloq falsafasi bo'yicha tarbiyalash usullari haqida yozilgan.
Janka, M. (Hrsg., 2017): Latein. Didaktik. Praxishandbuch für die Sekundarstufe I und II
Creators: name: Glücklich, Hans-Joachim
Publisher: name: Forum Classicum
Year: 2020

description: Rezension zu: Janka, M. (Hrsg., 2017): Latein. Didaktik. Praxishandbuch für die Sekundarstufe I und II, Berlin, Cornelsen, 256 S., (ISBN 978-3-589-15531-6)
description: Forum Classicum, Nr. 4 (2019): Forum Classicum
Specific "scientific" data structures, and their processing
Creators: name: Karczmarczuk, Jerzy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Mathematical Software (cs.MS)
subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: Programming physicists use, as all programmers, arrays, lists, tuples, records, etc., and this requires some change in their thought patterns while converting their formulae into some code, since the "data structures" operated upon, while elaborating some theory and its consequences, are rather: power series and Padé approximants, differential forms and other instances of differential algebras, functionals (for the variational calculus), trajectories (solutions of differential equations), Young diagrams and Feynman graphs, etc. Such data is often used in a [semi-]numerical setting, not necessarily "symbolic", appropriate for the computer algebra packages. Modules adapted to such data may be "just libraries", but often they become specific, embedded sub-languages, typically mapped into object-oriented frameworks, with overloaded mathematical operations. Here we present a functional approach to this philosophy. We show how the usage of Haskell datatypes and - fundamental for our tutorial - the application of lazy evaluation makes it possible to operate upon such data (in particular: the "infinite" sequences) in a natural and comfortable manner.
description: In Proceedings DSL 2011, arXiv:1109.0323
Ausstellungskalender
Creators: name: Redaktion, Die
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 25 Nr. 5 (1972): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
The design and development of lyotropic liquid crystalline lipidic nanoparticles in enhancing daptomycin’s antibacterial effect against methicillin-resistant Staphylococcus aureus
Creators: name: LIM, CHIA XIN
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 310799
subject: Microbiology not elsewhere classified
classificationCode: 310908
subject: Animal physiology - biophysics
classificationCode: 320802
subject: Human biophysics
classificationCode: 401699
subject: Materials engineering not elsewhere classified

description: Increasing reports of daptomycin resistance in methicillin-resistant Staphylococcus aureus (MRSA), especially in the form of mprF and cls2 mutations pose a significant threat to human health. Therefore, it is important to improve the antibacterial efficacy of daptomycin and extend its lifespan as the last-line defense against multidrug-resistant (MDR) MRSA infections. In an attempt to resolve the daptomycin resistance crisis, this thesis designed and developed phytantriol-based cubosomes packaged with daptomycin to achieve improved daptomycin antibacterial efficacy. This thesis also attempted to develop phytantriol-based antimicrobial lipidic nanoparticles as a novel antibacterial agent that could be used alone or in combination with daptomycin The data from this thesis are valuable for the future treatment of Staphylococcus aureus infections.
Investigating the role of the atypical kinase/ATPase RIOK-1 in C. elegans
Creators: name: NOVAKOVIC, STEVAN
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310404
subject: Evolution of developmental systems
classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology
classificationCode: 320407
subject: Innate immunity

description: Ribosomes are complex molecular machines that synthesise the cell's proteins. Assembling ribosomes is complex and requires input from over 200 different proteins. Many of these proteins also have additional roles within the cell, however, these additional roles are not well understood. This thesis used a microscopic worm organism, C. elegans, to examine the function of a ribosome assembly protein called RIOK-1. Important roles for RIOK-1 in regulating development, metabolism and immunity were identified. Mutations in RIOK-1 commonly associated with various cancers, and therefore these results may help us better understand the role of RIOK-1 in human health and disease.
Effect of a fermion on quantum phase transitions in bosonic systems
Creators: name: Iachello, F.
name: Leviatan, A.
name: Petrellis, D.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The effect of a fermion with angular momentum j on quantum phase transitions of a (s,d) bosonic system is investigated. It is shown that the presence of a fermion strongly modifies the critical value at which the transition occurs, and its nature, even for small and moderate values of the coupling constant. The analogy with a bosonic system in an external field is mentioned. Experimental evidence for precursors of quantum phase transitions in bosonic systems plus a fermion (odd-even nuclei) is presented.
description: 4 pages, 3 figures
Pseudospin dynamics in multimode polaritonic Josephson junctions
Creators: name: Pavlovic, G.
name: Malpuech, G.
name: Shelykh, I. A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We analyzed multimode Josephson junctions with exciton-polaritons (polaritonic Josephson junctions) when several coupling mechanisms of fundamental and excited states are present. The applied method is based on Keldysh-Green function formalism and takes into account polariton pseudospin. We found that mean value of circular polarization degree in intrinsic Josephson oscillations and microscopic quantum self-trapping follow an oscillator behavior whose renormalizes due to intermode interactions. The effect of an additional transfer of particles over junction barrier occurring in multimode approximation in combination with common Josephson tunneling is discussed in regime of dynamical separation of two polarizations.
description: 12 pages, 4 figures
Elucidating the composition and functions of Remodel the Structure of Chromatin (RSC) complex in Candida albicans
Creators: name: K B, Vinutha
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology
classificationCode: 310599
subject: Genetics not elsewhere classified

description: The human fungal pathogen Candida albicans utilizes several traits to thrive in its host. As many of such responses are governed by gene expression programs, proteins that remodel the chromatin structure are believed to affect the fitness of C. albicans. This thesis shows that the only essential chromatin remodeler RSC is compositionally distinct in C. albicans and impacts the survival, adaptation and virulence of this pathogen in vivo and a range of in vitro conditions. These findings highlight the cross-species divergence of RSC functions in fungi and set the groundwork to target chromatin remodelers for antifungal interventions.
The Role of Fibroblast Growth Factor Receptors in Cancer
Creators: name: CHEW, NICOLE JING SIAN
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 321199
subject: Oncology and carcinogenesis not elsewhere classified
classificationCode: 310111
subject: Signal transduction
classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology

description: Breast cancer accounts for a quarter of all cancers and ranks as the second most common cancer in the world. In particular, triple negative breast cancer is aggressive and lacks targeted therapeutic options. Hence, new therapeutic targets need to be identified for personalised treatment strategies to improve patient outcomes. My PhD work describes abnormal fibroblast growth factor receptors (FGFRs) as therapeutic targets in breast cancer. It investigates two FGFR fusions, including the identification of a novel FGFR fusion, and the identification of novel targeted combinations involving FGFR. The findings in my PhD support targeting FGFRs as a precision medicine approach for specific cancers.
Ausstellungskalender
Creators: name: Redaktion, Die
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 27 Nr. 10 (1974): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Structural and functional characterisation of MACPF proteins in immunity
Creators: name: Bayly-Jones, Charles
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 310908
subject: Animal physiology - biophysics
classificationCode: 320802
subject: Human biophysics
classificationCode: 340202
subject: Crystallography
classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310299
subject: Bioinformatics and computational biology not elsewhere classified
classificationCode: 340403
subject: Characterisation of biological macromolecules
classificationCode: 320499
subject: Immunology not elsewhere classified
classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology
classificationCode: 310112
subject: Structural biology (incl. macromolecular modelling)

description: The human immune system consists of hundreds of thousands of nanoscopic molecular machines, referred to as proteins. This thesis explores a group called pore forming proteins, which self-assemble into ring structures in order to insert into and puncture cell barriers. These agents maintain human health by targeting and destroying rogue cells or invading pathogens. If left unchecked, however, the immune system can damage the body. This thesis visualised nanoscopic details of the architecture and organisation of these potent effectors. These findings provide an understanding of the function of these immune weapons and the underlying molecular mechanisms of certain immune diseases.
The Fractional Quantum Hall Effect of Tachyons in a Topological Insulator Junction
Creators: name: Apalkov, Vadim M.
name: Chakraborty, Tapash
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We have studied the tachyonic excitations in the junction of two topological insulators in the presence of an external magnetic field. The Landau levels, evaluated from an effective two-dimensional model for tachyons, and from the junction states of two topological insulators, show some unique properties not seen in conventional electrons systems or in graphene. The $ν=1/3$ fractional quantum Hall effect has also a strong presence in the tachyon system.
description: 5 pages, 3 figures
A new AF gravitational instanton
Creators: name: Chen, Yu
name: Teo, Edward
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It has long been conjectured that the Euclidean Schwarzschild and Euclidean Kerr instantons are the only non-trivial asymptotically flat (AF) gravitational instantons. In this letter, we show that this conjecture is false by explicitly constructing a new two-parameter AF gravitational instanton with a U(1)xU(1) isometry group, using the inverse-scattering method. It has Euler number χ=3 and Hirzebruch signature τ=1, and its global topology is CP^2 with a circle S^1 removed appropriately. Various other properties of this gravitational instanton are also discussed.
description: 10 pages, 2 figures, LaTeX
Investigating the role of the SAGA complex in transcription of protein-coding genes
Creators: name: ADAMUS, KLAUDIA
Publisher: name: Monash University
Year: 2021
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310112
subject: Structural biology (incl. macromolecular modelling)
classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology

description: Transcription is an essential cellular process that controls the flow of genetic information in biological systems. Spt-Ada-Gcn5-Acetyltransferase (SAGA) complex plays several key regulatory roles during protein-coding gene transcription and is conserved across eukaryotes. However, how SAGA synchronises its distinct functions to maintain optimal regulation of gene transcription is poorly understood. This study uncovers the interplay between SAGA and the general transcription machinery components critical for the optimal regulation of transcription and reveals high structural and functional homology between SAGA and its isoform SLIK. Knowledge gained from this project adds to the understanding of the conserved transcriptional regulatory mechanisms.
Transformation of quantum photonic circuit models by term rewriting
Creators: name: Sarma, Gopal
name: Hamerly, Ryan
name: Tezak, Nikolas
name: Pavlichin, Dmitri S.
name: Mabuchi, Hideo
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The development of practical methods for synthesis and verification of complex photonic circuits presents a grand challenge for the nascent field of quantum engineering. Of course, classical electrical engineering provides essential foundations and serves to illustrate the degree of sophistication that can be achieved in automated circuit design. In this paper we explore the utility of term rewriting approaches to the transformation of quantum circuit models, specifically applying rewrite rules for both reduction/verification and robustness analysis of photonic circuits for autonomous quantum error correction. We outline a workflow for quantum photonic circuit analysis that leverages the Modelica framework for multi-domain physical modeling, which parallels a previously described approach based on VHSIC Hardware Description Language (VHDL).
description: 13 pages, 7 figures. Supplementary Data included
Implementing Explicit and Finding Implicit Sharing in Embedded DSLs
Creators: name: Kiselyov, Oleg
Publisher: name: arXiv
Year: 2011
Subjects: subject: Programming Languages (cs.PL)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: Aliasing, or sharing, is prominent in many domains, denoting that two differently-named objects are in fact identical: a change in one object (memory cell, circuit terminal, disk block) is instantly reflected in the other. Languages for modelling such domains should let the programmer explicitly define the sharing among objects or expressions. A DSL compiler may find other identical expressions and share them, implicitly. Such common subexpression elimination is crucial to the efficient implementation of DSLs. Sharing is tricky in embedded DSL, since host aliasing may correspond to copying of the underlying objects rather than their sharing. This tutorial summarizes discussions of implementing sharing in Haskell DSLs for automotive embedded systems and hardware description languages. The technique has since been used in a Haskell SAT solver and the DSL for music synthesis. We demonstrate the embedding in pure Haskell of a simple DSL with a language form for explicit sharing. The DSL also has implicit sharing, implemented via hash-consing. Explicit sharing greatly speeds up hash-consing. The seemingly imperative nature of hash-consing is hidden beneath a simple combinator language. The overall implementation remains pure functional and easy to reason about.
description: In Proceedings DSL 2011, arXiv:1109.0323
Nucleosomes in gene regulation: theoretical approaches
Creators: name: Teif, V. B.
name: Shkrabkou, A. V.
name: Egorova, V. P.
name: Krot, V. I.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Genomics (q-bio.GN)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: This work reviews current theoretical approaches of biophysics and bioinformatics for the description of nucleosome arrangements in chromatin and transcription factor binding to nucleosomal organized DNA. The role of nucleosomes in gene regulation is discussed from molecular-mechanistic and biological point of view. In addition to classical problems of this field, actual questions of epigenetic regulation are discussed. The authors selected for discussion what seem to be the most interesting concepts and hypotheses. Mathematical approaches are described in a simplified language to attract attention to the most important directions of this field.
Gedanken experiments with Casimir forces, vacuum energy, and gravity
Creators: name: Maclay, G. Jordan
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Gedanken experiments are used to explore properties of quantum vacuum energy that are currently challenging to explore experimentally. A constant lateral Casimir force is predicted to exist between two overlapping finite parallel plates at 0 K, otherwise it would be possible to extract an arbitrary amount of energy from the quantum vacuum. A rigid unpowered object cannot be accelerated by the quantum vacuum because of the translational symmetry of space. By considering systems in which vacuum energy and other forms of energy are exchanged, we demonstrate that a change ΔE in vacuum energy, whether positive or negative with respect to the free field, corresponds to an equivalent inertial mass and equivalent gravitational mass ΔM=ΔE/c^2. We consider the possibility of a gravitational shield, and show that, if it exists, the energy to operate it would have to cancel the net energy extracted from the gravitational field, otherwise we could extract an arbitrary amount of energy from the field.
description: 24 pages, 3 figures
REMEDIS Evaluation Toolkit
Creators: name: REMEDIS
Publisher: name: Zenodo
Year: 2025

description: The REMEDIS Toolkit is designed to empower educators, policymakers, and civil society organisations with practical resources to enhance media literacy and digital skills across diverse communities. Developed within the REMEDIS project, this toolkit provides research-based strategies, intervention models, and evaluation frameworks to foster critical engagement with digital media, combat misinformation, and promote responsible online participation.
Structural characterization and computer-aided redesign of the substrate binding pockets of the selection domains from mega-enzymes involved in glycopeptide antibiotic biosynthesis
Creators: name: HANSEN, MATHIAS HENNING
Publisher: name: Monash University
Year: 2020
Subjects: classificationCode: 340202
subject: Crystallography
classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310299
subject: Bioinformatics and computational biology not elsewhere classified
classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology
classificationCode: 310410
subject: Phylogeny and comparative analysis
classificationCode: 310510
subject: Molecular evolution
classificationCode: 310112
subject: Structural biology (incl. macromolecular modelling)

description: Teicoplanin is a glycopeptide antibiotic (GPAs)used to treat infections by Gram-positive bacterial pathogens. GPAs are natural products and due to their complex structure we rely on bacterial fermentation for their production. Consequently, we need to understand GPA biosynthesis to develop new compounds for clinical use. Herein, we structurally characterise an amino acid selection domain integral to the synthesis of the GPA, explore the evolution of these domains to reveal how ancestral forms of these proteins evolved to accept new amino acid building blocks, and learn how to modify these domains by understanding natural evolution in biosynthesis.
Mathematical Modeling of Transport and Degradation of Feedstuffs in the Small Intestine
Creators: name: Taghipoor, Masoomeh
name: Lescoat, Philippe
name: Georgelin, Christine
name: Licois, Jean-René
name: Barles, Guy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Dynamical Systems (math.DS)
subject: Biological Physics (physics.bio-ph)
subject: Tissues and Organs (q-bio.TO)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We describe a mathematical modeling of the digestion in the small intestine. The main interest of our work is to consider, at the same time, different aspects of the digestion i.e. the transport of the bolus all along the intestine, feedstuffs degradation according to the enzymes and local physical conditions, and nutrients absorption. A system of coupled ordinary differential equations is used to model these phenomena. The major unknowns of this system are the position of the bolus and its composition. This system of equations is solved numerically. We present different numerical computations for the degradation, absorption and transport of the bolus with acceptable accuracy with experimental data. The main feature and interest of this model are its generality. Even if we are at an early stage of development, our approach can be adapted to treat any kind of feedstuffs in any non-ruminant animal to predict the composition and velocity of bolus in the small intestine.
Neue Käthe Kollwitz-Literatur
Creators: name: Thiem, Gunther
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Rezension zu: Mina C. Klein und H. Arthur Klein: Käthe Kollwitz, Life in Art — illustrated, Holt, Rinhart and Winston, New York - Chicago - San Francisco 1972. $ 11.95.— Otto Nagel und Werner Timm: Käthe Kollwitz. Die Handzeichnungen (Oeuvrekatalog). Unter Mitarbeit von Sibylle Schallenberg-Nagel. 464 Seiten, 150 Tafeln und 1318 Abbildungen. Berlin. Henschelverlag 1972. 180.— DM Hella Robels: Käthe Kollwitz, Zeichnungen im Wallraf-Richartz-Museum Köln. Ausstellungskatalog, 30 Seiten, 40 Tafeln, 1973. DM 8.— Katalog der Ausstellung „Käthe Kollwitz", Frankfurter Kunstverein und Württembergischer Kunstverein Stuttgart 1973. Herausgegeben vom Frankfurter Kunstverein und einer Arbeitsgruppe des Kunstgeschichtlichen Instituts der Universität Frankfurt. Redaktion: Georg Bussmann. 44 S. mit 83 Abb. 2 S. Taf. DM 10.—.
description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 27 Nr. 8 (1974): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
The detection of human papilloma virus 16 L1 capsid protein and p16 in cervical lesions
Creators: name: Uranbolor, Jugder
name: Erdenetsogt, Dongobat
name: Galtsog, Lodon
name: Sarantuya, Jav
Publisher: name: Diagnostic Pathology
Year: 2015
Subjects: Immunohistochemistry; Human papillomavirus; Cervical cancer; p16

description: Background

Cervical cancer is the second most common type of cancer in women worldwide and also the second most common female malignancy in Mongolia. The association of p16 and hr-HPV in Asia and in more particular in Mongolia are still relatively unexplored. So we aimed to detect the immunohistochemistry expression of p16 and L1 protein of HPV16 and to investigate the combined expression of these markers in cervical lesions.

Methods

A total of 96 cases were selected from the records of Pathology services, National Cancer center of Mongolia. There were 50 cases diagnosed as LSIL and 46 cases diagnosed as HSIL. The immunohistochemical staining with p16 and HPV 16 L1 were done on all cases.

Results

The positive rate of HPV 16 L1 capsid protein was identified 74% in LSIL cases and 52% in HSIL cases.There were a significant difference for HPV16 in HSIL and LSIL groups.Immunohistochemistry of p16 staining shows 76% in  LSIL cases and 72% in HSIL cases. There was not a statistically significant difference for p16 in HSIL and LSIL groups. A chi square test was used to analyze the result and the obtained p value was <0.05.

Conclusion

The combination between hr-HPV and p16 is considered to be more useful, having a higher accuracy than hr-HPV or p16 alone. There is still critical need, to find other molecular surrogate markers, which can provide accurate information about which precursor lesions would progress toward cancer.
description: Diagnostic Pathology, 2015