cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance
Creators: name: Gupton, Stephanie L.
name: Gertler, Frank B.
name: Dent, Erik W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Axon outgrowth and guidance to the proper target requires the coordination of filamentous (F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape change and locomotion. Over the past two decades, our knowledge of the many guidance cues, receptors, and downstream signaling cascades involved in neuronal outgrowth and guidance has increased dramatically. Less is known, however, about how those cascades of information converge and direct appropriate remodeling and interaction of cytoskeletal polymers, the ultimate effectors of movement and guidance. During development, much of the communication that occurs between environmental guidance cues and the cytoskeleton takes place at the growing tip of the axon, the neuronal growth cone. Several articles on this topic focus on the “input” to the growth cone, the myriad of receptor types, and their corresponding cognate ligands. Others investigate the signaling cascades initiated by receptors and propagated by second messenger pathways (i.e., kinases, phosphatases, GTPases). Ultimately, this plethora of information converges on proteins that associate directly with the actin and microtubule cytoskeletons. The role of these cytoskeletal-associated proteins, as well as the cytoskeleton itself in axon outgrowth and guidance, is the subject of this article.
(400853) Robert More
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
CFTR, Mucins, and Mucus Obstruction in Cystic Fibrosis
Creators: name: Davis, C. William
name: Kreda, Silvia M.
name: Rose, Mary Callaghan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Mucus pathology in cystic fibrosis (CF) has been known for as long as the disease has been recognized and is sometimes called mucoviscidosis. The disease is marked by mucus hyperproduction and plugging in many organs, which are usually most fatal in the airways of CF patients, once the problem of meconium ileus at birth is resolved. After the CF gene, CFTR, was cloned and its protein product identified as a cAMP-regulated Cl− channel, causal mechanisms underlying the strong mucus phenotype of the disease became obscure. Here we focus on mucin genes and polymeric mucin glycoproteins, examining their regulation and potential relationships to a dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR). Detailed examination of CFTR expression in organs and different cell types indicates that changes in CFTR expression do not always correlate with the severity of CF disease or mucus accumulation. Thus, the mucus hyperproduction that typifies CF does not appear to be a direct cause of a defective CFTR but, rather, to be a downstream consequence. In organs like the lung, up-regulation of mucin gene expression by inflammation results from chronic infection; however, in other instances and organs, the inflammation may have a non-infectious origin. The mucus plugging phenotype of the β-subunit of the epithelial Na+ channel (βENaC)-overexpressing mouse is proving to be an archetypal example of this kind of inflammation, with a dehydrated airway surface/concentrated mucus gel apparently providing the inflammatory stimulus. Data indicate that the luminal HCO3− deficiency recently described for CF epithelia may also provide such a stimulus, perhaps by causing a mal-maturation of mucins as they are released onto luminal surfaces. In any event, the path between CFTR dysfunction and mucus hyperproduction has proven tortuous, and its unraveling continues to offer its own twists and turns, along with fascinating glimpses into biology.
(400850) Patrick Monoghan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A generalization of Eulerian numbers via rook placements
Creators: name: Banaian, Esther
name: Butler, Steve
name: Cox, Christopher
name: Davis, Jeffrey
name: Landgraf, Jacob
name: Ponce, Scarlitte
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05A15, 05A10

description: We consider a generalization of Eulerian numbers which count the number of placements of $cn$ "rooks" on an $n\times n$ board where there are exactly $c$ rooks in each row and each column, and exactly $k$ rooks below the main diagonal. The standard Eulerian numbers correspond to the case $c=1$. We show that for any $c$ the resulting numbers are symmetric and give generating functions of these numbers for small values of $k$.
description: 15 pages
Extracellular Matrix Proteins in Hemostasis and Thrombosis
Creators: name: Hynes, Richard O.
name: Bergmeier, Wolfgang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The adhesion and aggregation of platelets during hemostasis and thrombosis represents one of the best-understood examples of cell–matrix adhesion. Platelets are exposed to a wide variety of extracellular matrix (ECM) proteins once blood vessels are damaged and basement membranes and interstitial ECM are exposed. Platelet adhesion to these ECM proteins involves ECM receptors familiar in other contexts, such as integrins. The major platelet-specific integrin, αIIbβ3, is the best-understood ECM receptor and exhibits the most tightly regulated switch between inactive and active states. Once activated, αIIbβ3 binds many different ECM proteins, including fibrinogen, its major ligand. In addition to αIIbβ3, there are other integrins expressed at lower levels on platelets and responsible for adhesion to additional ECM proteins. There are also some important nonintegrin ECM receptors, GPIb-V-IX and GPVI, which are specific to platelets. These receptors play major roles in platelet adhesion and in the activation of the integrins and of other platelet responses, such as cytoskeletal organization and exocytosis of additional ECM ligands and autoactivators of the platelets.
Eye Development and Retinogenesis
Creators: name: Heavner, Whitney
name: Pevny, Larysa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Three embryonic tissue sources—the neural ectoderm, the surface ectoderm, and the periocular mesenchyme—contribute to the formation of the mammalian eye. For this reason, the developing eye has presented an invaluable system for studying the interactions among cells and, more recently, genes, in specifying cell fate. This article describes how the eye primordium is specified in the anterior neural plate by four eye field transcription factors and how the optic vesicle becomes regionalized into three distinct tissue types. Specific attention is given to how cross talk between the optic vesicle and surface ectoderm contributes to lens and optic cup formation. This article also describes how signaling networks and cell movements set up axes in the optic cup and establish the multiple cell fates important for vision. How multipotent retinal progenitor cells give rise to the six neuronal and one glial cell type in the mature retina is also explained. Finally, the history and progress of cellular therapeutics for the treatment of degenerative eye disease is outlined. Throughout this article, special attention is given to how disruption of gene function causes ocular malformation in humans. Indeed, the accessibility of the eye has contributed much to our understanding of the basic processes involved in mammalian development.
title: COVID-19 Pneumonia - Artificial Intelligence soft vs. radiologists' eyes
Creators: name: Stoicescu, Emil-Robert
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Computer applications
subject: Lung
subject: CT
subject: CT-High Resolution
subject: Image manipulation / Reconstruction
subject: Computer Applications-Detection, diagnosis
subject: Computer Applications-Teleradiology
subject: Health policy and practice
subject: Education and training
subject: Image verification
subject: Infection

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Coronavirus disease had been widely spread around the world since the ending of 2019, with over 250 million cases of infection until now (1,2). Meanwhile, numerous techniques have been devised for contributing to earlier and efficient detection of...
(400851) Alexander More
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Imaging of rare forms of otosclerosis
Creators: name: IHSSANE, GHANBOURI
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Ear / Nose / Throat
subject: Head and neck
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Dysplasias

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Otosclerosis is a primary focal osteodystrophy of the otic capsule affecting genetically predisposed individuals and whose etiology remains unknown (1). The histologically normal endochondral bone of the otic capsule is replaced by disorganized foci...
title: Clarifying Causes for Olfactory Bulb Agenesis: Is This Always Kallmann Syndrome ?
Creators: name: Aydemir, Sinem
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Neuroradiology peripheral nerve
subject: MR
subject: Diagnostic procedure
subject: Congenital

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To define conditions that can cause the absence of olfactory bulbs and evaluate their radiological appearance...
Information Hiding as a Challenge for Malware Detection
Creators: name: Mazurczyk, Wojciech
name: Caviglione, Luca
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Information hiding techniques are increasingly utilized by the current malware to hide its existence and communication attempts. In this paper we highlight this new trend by reviewing the most notable examples of malicious software that shows this capability.
description: 9 pages, 1 table
(400845) Margaret [Millar]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Genomic Imprinting and Epigenetic Control of Development
Creators: name: Magnuson, Terry
name: Fedoriw, Andrew
name: Mugford, Joshua
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Epigenetic mechanisms are extensively utilized during mammalian development. Specific patterns of gene expression are established during cell fate decisions, maintained as differentiation progresses, and often augmented as more specialized cell types are required. Much of what is known about these mechanisms comes from the study of two distinct epigenetic phenomena: genomic imprinting and X-chromosome inactivation. In the case of genomic imprinting, alleles are expressed in a parent-of-origin-dependent manner, whereas X-chromosome inactivation in females requires that only one X chromosome is active in each somatic nucleus. As model systems for epigenetic regulation, genomic imprinting and X-chromosome inactivation have identified and elucidated the numerous regulatory mechanisms that function throughout the genome during development.
The Effects of Superhigh Magnetic Fields on Equations of States of Neutron Stars
Creators: name: Gao, Z. F.
name: Wang, N.
name: Xu, Y.
name: Shan, H.
name: Li, X. D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: By introducing Dirac ?-function in superhigh magnetic field, we deduce a general formula for pressure of degenerate and relativistic electrons, Pe, which is suitable for superhigh magnetic fields, discuss the quantization of Landau levels of electrons, and consider the quantum electrodynamic(QED) effects on the equations of states (EOSs) for different matter systems. The main conclusions are as follows: the stronger the magnetic field strength, the higher the electron pressure becomes; compared with a common radio pulsar, a magnetar could be a more compact oblate spheroid-like deformed neutron star due to the anisotropic total pressure; and an increase in the maximum mass of a magnetar is expected because of the positive contribution of the magnetic field energy to the EOS of the star. Since this is an original work in which some uncertainties could exist, to further modify and perfect our theory model should be considered in our future studies.
description: arXiv admin note: substantial text overlap with arXiv:1312.1442
title: Role of locoregional treatments in patients with kidney graft neoplasm (< 4 cm ): literature review and results of a Multidisciplinary Consensus Conference.
Creators: name: Tanzilli, Alessandro
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Interventional non-vascular
subject: Interventional vascular
subject: Kidney
subject: Percutaneous
subject: Ablation procedures
subject: Embolisation
subject: Cancer
subject: Neoplasia
subject: Transplantation

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Allograft malignancies occur in 0.2% to 0.34% of renal transplant patients. Since the viability of the graft is as important as the oncological control, the gold standard therapy for these patients is still represented by the Nephron Sparing...
Magnetization Process of the Spin-S Kagome-Lattice Heisenberg Antiferromagnet
Creators: name: Nakano, Hiroki
name: Sakai, Toru
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The magnetization process of the spin-S Heisenberg antiferromagnet on the kagome lattice is studied by the numerical-diagonalization method. Our numerical-diagonalization data for small finite-size clusters with S=1, 3/2, 2, and 5/2 suggest that a magnetization plateau appears at one-third of the height of the saturation in the magnetization process irrespective of S. We discuss the S dependences of the edge fields and the width of the plateau in comparison with recent results obtained by real-space perturbation theory.
description: 5pages, 4figures, to be published in J. Phys. Soc. Jpn
Dialogues about geometry and light
Creators: name: Bermudez, David
name: Drori, Jonathan
name: Leonhardt, Ulf
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Throughout human history, people have used sight to learn about the world, but only in relatively recent times the science of light has been developed. Egyptians and Mesopotamians made the first known lenses out of quartz, giving birth to what was later known as optics. On the other hand, geometry is a branch of mathematics that was born from practical studies concerning lengths, areas and volumes in the early cultures, although it was not put into axiomatic form until the 3rd century BC. In this work, we will discuss the connection between these two timeless topics and show some "new things in old things". There has been several works in this direction, but taking into account the didactic approach of the Enrico Fermi Summer School, we would like to address the subject and our audience in a new light.
description: 23 pages, 9 figures, 27 references
Ultrastructure of Synapses in the Mammalian Brain
Creators: name: Harris, Kristen M.
name: Weinberg, Richard J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The morphology and molecular composition of synapses provide the structural basis for synaptic function. This article reviews the electron microscopy of excitatory synapses on dendritic spines, using data from rodent hippocampus, cerebral cortex, and cerebellar cortex. Excitatory synapses have a prominent postsynaptic density, in contrast with inhibitory synapses, which have less dense presynaptic or postsynaptic specializations and are usually found on the cell body or proximal dendritic shaft. Immunogold labeling shows that the presynaptic active zone provides a scaffold for key molecules involved in the release of neurotransmitter, whereas the postsynaptic density contains ligand-gated ionic channels, other receptors, and a complex network of signaling molecules. Delineating the structure and molecular organization of these axospinous synapses represents a crucial step toward understanding the mechanisms that underlie synaptic transmission and the dynamic modulation of neurotransmission associated with short- and long-term synaptic plasticity.
title: The attempt to give an unbiased view of the advantage that the vaccination has against Covid-19 in terms of damage caused to cardiac structures, as seen on TTE. The case-control study.
Creators: name: Sukmarova, Zulfiya
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: Echocardiography (transoesophageal)
subject: Acceptance testing
subject: Inflammation

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: To evaluate in patients who had COVID-19 or were vaccinated, as compared with the test group -TTE local qualities of the pericardium, -local and global measures of the myocardial contractility, -local and global measures of diastolic...
Phenotypic plasticity in an ant with strong caste genotype association - Supplementary Material.
Creators: name: Kuhn, Alexandre
name: Darras, Hugo
name: Aron, Serge
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: The number of workers and queens, and the microsatellite data
(400846) James Brash Miller
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: The Effects of Body Posture on Vigilance Performance
Creators: name: Ammons, Jeremiah Gabriel
Publisher: name: Old Dominion University Libraries
Year: 2022

description: Drivers of vehicles that use a driving automation system were tasked with supervising the vehicle to ensure it was functioning properly. This task required drivers to stay vigilant of the roadway while being ready to intervene in the case of an unexpected hazard that the driving automation system may not have detected. This study investigated whether reclining a drivers’ seatback to more comfortable postures would affect their vigilance performance over time. Vigilance performance was measured by correct detections, false alarms, response sensitivity, response bias, and response time to hazardous events. Forty-five participants were recruited and randomly assigned to a postural condition with a seatback that was upright, slightly reclined, or very reclined. Their performance and comfort were measured over the course of a 40-minute driving task that used SAE Level-2 automation. Participants were tasked with classifying whether the neighboring vehicles were hazardous or safe. Based on our performance measures, we found a vigilance decrement that was potentially caused by cognitive underload stemming from the low task demand. We also found that posture did not affect any of the performance measures and that comfort ratings were similar despite the postural manipulation. This result indicates that drivers of vehicles with a driving automation system are free to adjust their seatback from an upright to very reclined posture without concern for their vigilance performance.
title: Madelung Disease: an overlooked cause for dyspnea and dysphagia
Creators: name: Urbano, Maria Luisa
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Head and neck
subject: CT
subject: MR
subject: Ultrasound
subject: Education
subject: History
subject: Education and training
subject: Inflammation
subject: Metabolic disorders

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: To review the physiopathology of Madelung disease. To illustrate radiological findings of Madelung disease, often overlooked and clinically...
On the Sparing Number of the Edge-Corona of Graphs
Creators: name: Chithra, K. P.
name: Germina, K. A.
name: Sudev, N. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Mathematics (math.GM)
subject: FOS: Mathematics
subject: 05C78

description: Let $\mathbb{N}_0$ be the set of all non-negative integers and $\mathcal{P}(\mathbb{N}_0)$ be its the power set. An integer additive set-indexer (IASI) of a graph $G$ is an injective function $f:V(G)\to \mathcal{P}(\mathbb{N}_0)$ such that the induced function $f^+:E(G) \to \mathcal{P}(\mathbb{N}_0)$ defined by $f^+ (uv) = f(u)+ f(v)$ is also injective, where $f(u)+f(v)$ is the sum set of $f(u)$ and $f(v)$. An integer additive set-indexer $f$ is said to be a weak integer additive set-indexer (weak IASI) if $|f^+(uv)|=\max(|f(u)|,|f(v)|)~\forall ~ uv\in E(G)$. The minimum number of singleton set-labeled edges required for the graph $G$ to admit an IASI is called the sparing number of the graph. In this paper, we discuss the admissibility of weak IASI by a particular type of graph product called the edge corona of two given graphs and determine the sparing number of the edge corona of certain graphs.
description: 10 pages, 1 figure, published. arXiv admin note: text overlap with arXiv:1407.5092
(400847) Elizabeth McGibbon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Distribution function of the Atoms of Spacetime and the Nature of Gravity
Creators: name: Padmanabhan, T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The fact that the equations of motion for matter remain invariant when a constant is added to the Lagrangian suggests postulating that the field equations of gravity should also respect this symmetry. This principle implies that: (1) the metric cannot be varied in any extremum principle to obtain the field equations; and (2) the stress-tensor of matter should appear in the variational principle through the combination $T_{ab}n^an^b$ where $n_a$ is an auxiliary null vector field, which could be varied to get the field equations. This procedure selects naturally the Lanczos-Lovelock models of gravity in $D$-dimensions and Einstein's theory in $D=4$. Identifying $n_a$ with the normals to the null surfaces in the spacetime leads to a thermodynamic interpretation for gravity, in the macroscopic limit. Several geometrical variables and the equation describing the spacetime evolution acquire a thermodynamic interpretation. Extending these ideas one level deeper, we can obtain this variational principle from a distribution function for the ``atoms of spacetime'', which counts the number of microscopic degrees of freedom of the geometry. This is based on the curious fact that the renormalized spacetime endows each event with zero volume, but finite area!
description: Invited review for the special issue on `Entropy in Quantum Gravity and Quantum Cosmology'; 35 pages; no figures
Phenotypic plasticity in an ant with strong caste genotype association - Supplementary Material
Creators: name: Kuhn, Alexandre
name: Darras, Hugo
name: Aron, Serge
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: The number of workers and queens, and the microsatellite data
Molecular dynamics study of Cl− permeation through cystic fibrosis transmembrane conductance regulator (CFTR)
Creators: name: Zeng, Zhi Wei
name: Linsdell, Paul
name: Pomès, Régis
Publisher: name: Zenodo
Year: 2023
Subjects: MOLE2

description: This record contains some files corresponding to some workflows used in our published journal article "Molecular dynamics study of Cl− permeation through cystic fibrosis transmembrane conductance regulator (CFTR)" (DOI: 10.1007/s00018-022-04621-7) Some files that are used to perform analysis that are not part of the standard analysis of MD are provided here. An example is the MOLE2 analysis -- because it is the only program I found that worked on path detection and parametrization in this channel.
description: In this repository there are: mdp files: for equilibration and production runs. One of the production runs have electric field gro files: CFTR protein states to aid orienting and aligning before applying analysis scripts tcl files: mainly pertains to the analysis of ions inside the pore MOLE2 related files: parameters are in "input.xml"; running MOLE2 using shell script "mole2tunnel.sh"; "mole2.py" has functions that help parse outputs of MOLE2 We are experimenting this format of standardized repositories for research work. For inquiries, contact author Zhi Wei Zeng at wilson.zeng@mail.utoronto.ca
HIV Pathogenesis: Dynamics and Genetics of Viral Populations and Infected Cells
Creators: name: Swanstrom, Ronald
name: Coffin, John
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: In the absence of treatment, HIV-1 infection, usually starting with a single virion, leads inexorably to a catastrophic decline in the numbers of CD4+ T cells and to AIDS, characterized by numerous opportunistic infections as well as other symptoms, including dementia and wasting. In the 30 years since the AIDS pandemic came to our attention, we have learned a remarkable amount about HIV-1, the responsible virus—the molecular details about how it functions and interacts with the host cell, its evolution within the host, and the countermeasures it has evolved to overcome host defenses against viral infection. Despite these advances, we remain remarkably ignorant about how HIV-1 infection leads to disease and the death of the human host. In this brief article, we introduce and discuss important lessons that we have learned by examining the dynamics of viral populations and infected cells. These studies have revealed important features of the virus–host interaction that now form the basis of our understanding of the importance and consequence of ongoing viral replication during HIV-1 infection.
title: Vincenzo Latina: οι ανακατασκευές του παρελθόντος
title: Vincenzo Latina: reconstructions of the past
Creators: name: Καλατζιδακης Ευστρατιος
Publisher: name: Technical University of Crete
Year: 2020

description: Αφετηρία αυτής της έρευνας αποτελεί το έργο του ιταλού αρχιτέκτονα Vincenzo Latina. Το στοιχείο που ώθησε την αναζήτηση για τον συγκεκριμένο αρχιτέκτονα ήταν η σχεδιαστική του λογική, ο τρόπος σκέψης του και οι επεμβάσεις του στο ιστορικό κέντρο των Συρακουσών όπου ανέπτυξε τη δική του ξεχωριστή προσέγγιση της ιστορικής πόλης - γενέτειράς του. Η  παρούσα ερευνητική εργασία αποτελεί την μελέτη αυτού του διαλόγου που πραγματοποιεί ο Vincenzo Latina με την ιστορική πόλη. Αρχικά παρουσιάζονται οι διαφορετικές πτυχές της ζωής του Vincenzo Latina: οι σπουδές του, το πεδίο εργασίας του καθώς και οι επιρροές στο έργου του. Τα τρία αυτά στοιχεία συντελούν στην ολοκλήρωση του χαρακτήρα του και στην διαμόρφωση της αρχιτεκτονικής του. Τέλος, πραγματοποιείται η μετάβαση στο υλοποιημένο έργο του αρχιτέκτονα, όπου αναλύονται τρία έργα του στο ιστορικό κέντρο των Συρακουσών, στο νησί της Ορτυγίας.
Ethical Statement;Material and methods;Suppl Tables;Suppl Figure from Inverted intergeneric introgression between critically endangered kipunjis and yellow baboons in two disjunct populations.
Creators: name: Zinner, Dietmar
name: Idrissa S. Chuma
name: Knauf, Sascha
name: Roos, Christian
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Additional information on Ethical Statement;Additional information on Material and methods. Sample Collection; Laboratory methods; Phylogenetic analysis; References;Suppl. Table 1 List of samples. ID, clade, geographic provenance and accession numbers; Suppl. Table 2. Estimated divergence ages of mtDNA lineages in million years (Ma); Suppl. Table 3. Results from the Kishino-Hasegawa (KH) and Shimodaira-Hasegawa (SH) tests;Suppl Fig 1 is showing an uncollapsed chronogram showing phylogenetic relationships and divergence times among various baboon and kipunji mtDNA lineages
title: Non-specific findings on pulmonary CTA in patients with acute pulmonary embolism
Creators: name: Oganesyan, Anait
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: CT-Angiography
subject: Treatment effects
subject: Acute

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: - To demonstrate the types and occurrence of nonspecific pulmonary findings on CTA in patients with acute pulmonary embolism (PE). - To understand the sources ofthese findings and approach to...
Improved Utility-based Congestion Control for Delay-Constrained Communication
Creators: name: D'Aronco, Stefano
name: Toni, Laura
name: Mena, Sergio
name: Zhu, Xiaoqing
name: Frossard, Pascal
Publisher: name: arXiv
Year: 2015
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Due to the presence of buffers in the inner network nodes, each congestion event leads to buffer queueing and thus to an increasing end-to-end delay. In the case of delay sensitive applications, a large delay might not be acceptable and a solution to properly manage congestion events while maintaining a low end-to-end delay is required. Delay-based congestion algorithms are a viable solution as they target to limit the experienced end-to-end delay. Unfortunately, they do not perform well when sharing the bandwidth with congestion control algorithms not regulated by delay constraints (e.g., loss-based algorithms). Our target is to fill this gap, proposing a novel congestion control algorithm for delay-constrained communication over best effort packet switched networks. The proposed algorithm is able to maintain a bounded queueing delay when competing with other delay-based flows, and avoid starvation when competing with loss-based flows. We adopt the well-known price-based distributed mechanism as congestion control, but: 1) we introduce a novel non-linear mapping between the experienced delay and the price function and 2) we combine both delay and loss information into a single price term based on packet interarrival measurements. We then provide a stability analysis for our novel algorithm and we show its performance in the simulation results carried out in the NS3 framework. Simulation results demonstrate that the proposed algorithm is able to: achieve good intra-protocol fairness properties, control efficiently the end-to-end delay, and finally, protect the flow from starvation when other flows cause the queuing delay to grow excessively.
(400848) [Elizabeth Miller Cleland] Josephine Miller
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Signaling Pathways that Control Cell Proliferation
Creators: name: Xiong, Yue
name: Duronio, Robert J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Cells decide to proliferate or remain quiescent using signaling pathways that link information about the cellular environment to the G1 phase of the cell cycle. Progression through G1 phase is controlled by pRB proteins, which function to repress the activity of E2F transcription factors in cells exiting mitosis and in quiescent cells. Phosphorylation of pRB proteins by the G1 cyclin-dependent kinases (CDKs) releases E2F factors, promoting the transition to S phase. CDK activity is primarily regulated by the binding of CDK catalytic subunits to cyclin partners and CDK inhibitors. Consequently, both mitogenic and antiproliferative signals exert their effects on cell proliferation through the transcriptional regulation and ubiquitin-dependent degradation of cyclins and CDK inhibitors.
title: CT-perfusion and diffusion-weighted MRI in differential diagnostic of solid renal tumors
Creators: name: Golbitc, Aleksandra
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Kidney
subject: CT
subject: MR-Diffusion/Perfusion
subject: Contrast agent-intravenous
subject: Cancer
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Renal masses vary widely in histology and aggressiveness, and include benign renal tumors and renal cell carcinomas that can be either indolent or aggressive. Most of them are indeterminate at CT and MRI and can present as diagnostic dilemmas for...
A Fourier Restriction Theorem For A Twodimensional Surface Of Finite Type
Creators: name: Buschenhenke, Stefan
name: Müller, Detlef
name: Vargas, Ana
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: The problem of $L^p(R^3)\to L^2(S)$ Fourier restriction estimates for smooth hypersurfaces S of finite type in R^3 is by now very well understood for a large class of hypersurfaces, including all analytic ones. In this article, we take up the study of more general $L^p(R^3)\to L^q(S)$ Fourier restriction estimates, by studying a prototypical class of two-dimensional surfaces with strongly varying curvature conditions. Our approach is based on an adaptation of the so-called bilinear method. We discuss several new features arising in the study of this problem.
Ethical Statement;Material and methods;Suppl Tables;Suppl Figure from Inverted intergeneric introgression between critically endangered kipunjis and yellow baboons in two disjunct populations
Creators: name: Zinner, Dietmar
name: Idrissa S. Chuma
name: Knauf, Sascha
name: Roos, Christian
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: Additional information on Ethical Statement;Additional information on Material and methods. Sample Collection; Laboratory methods; Phylogenetic analysis; References;Suppl. Table 1 List of samples. ID, clade, geographic provenance and accession numbers; Suppl. Table 2. Estimated divergence ages of mtDNA lineages in million years (Ma); Suppl. Table 3. Results from the Kishino-Hasegawa (KH) and Shimodaira-Hasegawa (SH) tests;Suppl Fig 1 is showing an uncollapsed chronogram showing phylogenetic relationships and divergence times among various baboon and kipunji mtDNA lineages
I-Love-Q relations for a gravastar and the approach to the black-hole limit
Creators: name: Pani, Paolo
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The multipole moments and the tidal Love numbers of neutron stars and quark stars satisfy certain relations which are almost insensitive to the star's internal structure. A natural question is whether the same relations hold for different compact objects and how they possibly approach the black-hole limit. Here we consider "gravastars", which are hypothetical compact objects sustained by their internal vacuum energy. Such solutions have been proposed as exotic alternatives to the black-hole paradigm because they can be as compact as black holes and exist in any mass range. By constructing slowly-rotating, thin-shell gravastars to quadratic order in the spin, we compute the moment of inertia $I$, the mass quadrupole moment $Q$, and the tidal Love number $λ$ in exact form. The $I$-$λ$-$Q$ relations of a gravastar are dramatically different from those of an ordinary compact star, but the black-hole limit is continuous, i.e. these quantities approach their Kerr counterparts when the compactness is maximum. Therefore, such relations can be used to discern a gravastar from an ordinary compact star, but not to break the degeneracy with the black-hole case. Based on these results, we conjecture that the full multipolar structure and the tidal deformability of a spinning, ultracompact gravastar are identical to those of a Kerr black hole. The approach to the black-hole limit is nonpolynomial, thus differing from the critical behavior recently found for strongly anisotropic neutron stars.
description: 10 pages, 2 figures, v2: various improvements, to appear in PRD, v3: erratum available as an ancillary file and at https://www.dropbox.com/s/0d1gsgy0idqtihi/erratum_1506.06050.pdf?dl=0 correcting the final result for the moment of inertia and for the tidal Love number
(400849) James John Miller
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Bias in linear model power and sample size calculation due to estimating noncentrality
Creators: name: Muller, Keith E.
name: Taylor, Douglas J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Data analysts frequently calculate power and sample size for a planned study using mean and variance estimates from an initial trial. Hence power, or the sample size needed to achieve a fixed power, varies randomly. Such calculations can be very inaccurate in the General Linear Univariate Model (GLUM). Biased noncentrality estimators and censored power calculations create inaccuracy. Censoring occurs if only certain outcomes of an initial trial lead to a power calculation. For example, a confirmatory study may be planned (and a sample size estimated) only following a significant result in the initial trial.
The theory of stochastic cosmological lensing
Creators: name: Fleury, Pierre
name: Larena, Julien
name: Uzan, Jean-Philippe
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: On the scale of the light beams subtended by small sources, e.g. supernovae, matter cannot be accurately described as a fluid, which questions the applicability of standard cosmic lensing to those cases. In this article, we propose a new formalism to deal with small-scale lensing as a diffusion process: the Sachs and Jacobi equations governing the propagation of narrow light beams are treated as Langevin equations. We derive the associated Fokker-Planck-Kolmogorov equations, and use them to deduce general analytical results on the mean and dispersion of the angular distance. This formalism is applied to random Einstein-Straus Swiss-cheese models, allowing us to: (1) show an explicit example of the involved calculations; (2) check the validity of the method against both ray-tracing simulations and direct numerical integrations of the Langevin equation. As a byproduct, we obtain a post-Kantowski-Dyer-Roeder approximation, accounting for the effect of tidal distortions on the angular distance, in excellent agreement with numerical results. Besides, the dispersion of the angular distance is correctly reproduced in some regimes.
description: 37+13 pages, 8 figures. A few typos corrected. Matches published version
title: Eye for Radiologist's Eye: Highlighting Imaging Features of Orbital Apex Pathologies
Creators: name: Sajid, Sadia
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Anatomy
subject: Eyes
subject: Head and neck
subject: CT
subject: MR
subject: PACS
subject: Education
subject: Imaging sequences
subject: Statistics
subject: FOS: Mathematics
subject: Education and training
subject: Epidemiology
subject: Pathology

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: 1. To elucidate the applied anatomy of the orbital apex. 2. To correlate the radiological features with the clinical cues with regards to various orbital apex pathologies. 3. To interpret the radiological features of the orbital apex pathologies and...
title: The importance of cardiac MR in risk assessment of sudden heart death in patients with hypertrophic cardiomyopathy
Creators: name: Nedeljkovic-Arsenovic, Olga
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: MR
subject: Safety
subject: Image verification

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Hypertrophic cardiomyopathy (HCM) is defined by the presence of increased left ventricular (LV) wall thickness for adults >15 mm in one or more LV myocardial segments which is not caused by abnormal loading conditions (eg hypertension) or ≥13 mm...
(400842) Laura MD Mill
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.