cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Enhanced tumor delivery and antitumor response of doxorubicin loaded albumin nanoparticles formulated based on a Schiff base
Creators: name: Xin, Junbo
name: Chen, Fangcheng
name: Ming, Xin
name: Ling, Hua
name: Webster, Thomas J.
name: Sun, Linlin
name: Li, Fang
name: Liu, Jianping
name: Zheng, Chunli
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: A novel method was developed here to prepare albumin-based nanoparticles (NPs) for improving the therapeutic and safety profiles of chemotherapeutic agents. This approach involved crosslinking bovine serum albumin (BSA) using a Schiff base-containing vanillin, into NPs and loading doxorubicin (DOX) into the NPs by incubation. The resultant NPs (DOX-BSA-V-NPs) displayed a particle size of 100.5±1.3 nm with a zeta potential of −23.05±1.45 mV and also showed high drug-loading efficiency and excellent stability with respect to storage and temperature. The encapsulation of DOX into the BSA-V-NPs was confirmed by dynamic scanning calorimetry and Raman spectroscopy. DOX-BSA-V-NPs exhibited a significantly faster DOX release at pH 6.5 than pH 7.4, as well as in a solution with a higher glutathione concentration. In vitro studies showed that the cellular uptake of DOX-BSA-V-NPs was time-dependent, concentration-dependent, and faster than free DOX, while the cytotoxicity of DOX-BSA-V-NPs (IC50 value of 3.693 μg/mL) was superior to free DOX (IC50 value of 4.007 μg/mL). More importantly, DOX-BSA-V-NPs showed a longer mean survival time of 24.83 days, a higher tumor inhibition rate of 56.66%, and a decreased distribution in the heart than other DOX formulations in animal studies using a tumor xenograft model. Thus, the vanillin-based albumin NPs were shown here to be a promising carrier for tumor-targeted delivery of chemotherapeutic agents and, thus, should be further studied.
$D_{s0}^{*}(2317)^+$ in the decay of $B_c$ into $J/ψDK$
Creators: name: Sun, Zhi-Feng
name: Bayar, M.
name: Fernandez-Soler, P.
name: Oset, E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper we study the relationship between the $D_{s0}^{*}(2317)^+$ resonance and the decay of the $B_c$ meson into $J/ψDK$. In this process, the $B_c$ meson decays first into $J/ψ$ and the quark pair $c\bar{s}$, and then the quark pair hadronizes into $DK$ or $D_sη$ components, which undergo final state interaction. This final state interaction, generating the $D_{s0}^{*}(2317)^+$ resonance, is described by the chiral unitary approach. With the parameters which allow us to match the pole position of the $D_{s0}^{*}(2317)^+$, we obtain the $DK$ invariant mass distribution of the decay $B_c\to J/ψDK$, and also the rate for $B_c\to J/ψD_{s0}^{*}(2317)$. The ratio of these two magnitude is then predicted.
description: 10 figures
A tetraethylene glycol coat gives gold nanoparticles long in vivo half-lives with minimal increase in size
Creators: name: Wilder, Jennifer C.
name: Willett, Julian D. S.
name: Lawrence, Marlon G.
name: Smithies, Oliver
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: In this study, we describe the experiments determining whether coating gold nanoparticles with tetraethylene glycol (TEG) provides pharmacologically relevant advantages, such as increased serum half-life and resistance to protein adsorption. Monodisperse TEG-coated, NaBH4-reduced gold nanoparticles with a hydrodynamic size comparable to albumin were synthesized by reducing gold chloride with NaBH4 under alkaline conditions in the presence of TEG-SH. The particles were characterized by gel electrophoresis, column chromatography, and transmission electron microscopy. The nanoparticles were subsequently injected intravenously into mice, and their half-lives and final destinations were determined via photometric analysis, light microscopy (LM), and transmission electron microscopy. The TEG particles had a long half-life (~400 minutes) that was not influenced by splenectomy. After 500 minutes of injection, TEG particles were found in kidney proximal tubule cell vesicles and in spleen red and white pulp. The particles induced apoptosis in the spleen red pulp but not in white pulp or the kidney. Some of the TEG particles appeared to have undergone ligand exchange reactions that increased their charge. The TEG particles were shown to be resistant to nonspecific protein adsorption, as judged by gel electrophoresis and column chromatography. These results demonstrate that naturally monodisperse, small-sized gold nanoparticles coated with TEG have long in vivo plasma half-lives, are minimally toxic, and are resistant to protein adsorption. This suggests that a TEG coating should be considered as an alternative to a polyethylene glycol coating, which is polydisperse and of much larger size.
Maternal diet quality in pregnancy and neonatal adiposity: the Healthy Start Study
Creators: name: Shapiro,
name: Dabelea,
name: Siega-Riz,
name: Glueck,
name: Friedman,
name: Starling,
name: Barbour,
name: Kaar,
name: Ringham,
name: Norris,
name: Crume,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Poor maternal diet in pregnancy can influence fetal growth and development. We tested the hypothesis that poor maternal diet quality during pregnancy would increase neonatal adiposity (percent fat mass, %FM) at birth by increasing the fat mass (FM) component of neonatal body composition.
Metabolic shifts toward fatty-acid usage and increased thermogenesis are associated with impaired adipogenesis in mice expressing human APOE4
Creators: name: Perez-Diaz,
name: Johnson,
name: Arbones-Mainar,
name: Garcia,
name: Maeda,
name: Torres-Perez,
name: Raber,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The Apolipoprotein E (APOE) gene encodes for three isoforms in the human population (APOE2, APOE3, and APOE4). While the role of APOE in lipid metabolism is well characterized, the specific metabolic signatures of the APOE isoforms, during metabolic disorders, remain unclear.
Novel measures of inflammation and insulin resistance are related to obesity and fitness in a diverse sample of 11–14 year olds: The HEALTHY Study
Creators: name: Otvos,
name: Drews,
name: Buse,
name: Jago,
name: Willi,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: GlycA is a novel serum marker of systemic inflammation. There is no information on GlycA in pediatric populations, how it differs by gender or its association with body mass index (BMI) or fitness. LP-IR is a serum measure of insulin resistance which is related to changes in BMI group in adolescents, but its relationship with fitness is unknown. The current study examined the independent associations between fitness and BMI with GlycA and LP-IR among US adolescents.
BMI loci and longitudinal BMI from adolescence to young adulthood in an ethnically diverse cohort
Creators: name: Gordon-Larsen,
name: Mohlke,
name: Lange,
name: Highland,
name: North,
name: Richardson,
name: Mazul,
name: Mullan Harris,
name: Graff,
name: Young,
name: Lange,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The association of obesity susceptibility variants with change in body mass index (BMI) across the life course is not well understood.
title: Searches for Axion-Like Particles in Rare Higgs Boson Decays with the ATLAS Detector
Creators: name: Ruby, Adam
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis presents a search for the decay of the Higgs boson to a Z boson and a light, pseudoscalar axion-like particle, where the Z boson decays to a pair of electrons or muons and the a particle decays to a pair of photons. The search is performed using 139 fb⁻¹ proton-proton LHC collision data at √s = 13 TeV collected by the ATLAS detector between 2015 and 2018. The mass of the ALP is assumed to be between 0.1 GeV and 10 GeV and the data are analysed in two selection categories; the merged category and the resolved category. Events are selected to the merged category if both photons from the ALP decay are reconstructed in the ATLAS calorimeter as a single cluster whereas resolved category events are such that they are separately reconstructed. The main background processes in this search are Z boson productions in association with photons or particle jets that are reconstructed as photons. No excess is observed for the ALP mass range chosen in this analysis. The data is in agreement with Standard Model predictions with upper limits on the branching ratio BR(h → Za) × BR(a → γγ) at 95 % confidence level found to vary from 0.1 % to 4 % depending on the mass value of the ALP.
Synthetic dimensions in integrated photonics: From optical isolation to 4D quantum Hall physics
Creators: name: Ozawa, Tomoki
name: Price, Hannah M.
name: Goldman, Nathan
name: Zilberberg, Oded
name: Carusotto, Iacopo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Recent technological advances in integrated photonics have spurred on the study of topological phenomena in engineered bosonic systems. Indeed, the controllability of silicon ring-resonator arrays has opened up new perspectives for building lattices for photons with topologically nontrivial bands and integrating them into photonic devices for practical applications. Here, we push these developments even further by exploiting the different modes of a silicon ring resonator as an extra dimension for photons. Tunneling along this synthetic dimension is implemented via an external time-dependent modulation that allows for the generation of engineered gauge fields. We show how this approach can be used to generate a variety of exciting topological phenomena in integrated photonics, ranging from a topologically-robust optical isolator in a spatially one-dimensional (1D) ring-resonator chain to a driven-dissipative analog of the 4D quantum Hall effect in a spatially 3D resonator lattice. Our proposal paves the way towards the use of topological effects in the design of novel photonic lattices supporting many frequency channels and displaying higher connectivities.
description: 18 pages, 7 figures
Advantages of nonclassical pointer states in postselected weak measurements
Creators: name: Turek, Yusuf
name: Maimaiti, W.
name: Shikano, Yutaka
name: Sun, Chang-Pu
name: Al-Amri, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences
subject: 81P15

description: We investigate, within the weak measurement theory, the advantages of non-classical pointer states over semi-classical ones for coherent, squeezed vacuum, and Schröinger cat states. These states are utilized as pointer state for the system operator $\hat{A}$ with property $\hat{A}^{2}=\hat{I}$, where $\hat{I}$ represents the identity operator. We calculate the ratio between the signal-to-noise ratio (SNR) of non-postselected and postselected weak measurements. The latter is used to find the quantum Fisher information for the above pointer states. The average shifts for those pointer states with arbitrary interaction strength are investigated in detail. One key result is that we find the postselected weak measurement scheme for non-classical pointer states to be superior to semi-classical ones. This can improve the precision of measurement process.
description: 8 pages, 5 figures
Exercise, adipokines and pediatric obesity: a meta-analysis of randomized controlled trials
Creators: name: Poblete-Aro,
name: Ceballos-Ceballos,
name: Hackney,
name: Ramírez-Vélez,
name: García-Hermoso,
name: Mota,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Adipokines are involved in the etiology of diabetes, insulin resistance, and the development of atherosclerosis and other latent-onset complications. The objective of this meta-analysis was to determine the effectiveness of exercise interventions on adipokines in pediatric obesity.
Quantum Secret Sharing and Random Hopping; Using single states instead of entanglement
Creators: name: Karimipour, Vahid
name: Asoudeh, Marzieh
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum protocols for secret sharing usually rely on multi-party entanglement which with present technology is very difficult to achieve. Recently it has been shown that sequential manipulation and communication of a single $d-$ level state can do the same task of secret sharing between $N$ parties, hence alleviating the need for entanglement. However the suggested protocol which is based on using mutually unbiased bases, works only when $d$ is a prime number. We propose a new sequential protocol which is valid for any $d$.
description: 5 pages, 3 figures, introduction revised, references added
Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations
Creators: name: Carlson,
name: Peters,
name: Lewis,
name: Wassel,
name: Hindorff,
name: Chen, Y-Di
name: Guo,
name: Fernandez-Rhodes,
name: Henderson,
name: Houston,
name: Haessler,
name: Irvin,
name: Gong,
name: Jackson,
name: North,
name: Cooper,
name: Schumacher,
name: Nguyen, K-Dh
name: Pankratz,
name: Allison,
name: Gu,
name: Matise,
name: Kooperberg,
name: Buyske,
name: Taylor,
name: Fornage,
name: Kuller,
name: Boerwinkle,
name: Yoneyama,
name: Buzková,
name: Bien,
name: Leppert,
name: Gross,
name: Pooler,
name: Rotter,
name: Ritchie,
name: Lim,
name: Ehret,
name: Chakravarti,
name: Le Marchand,
name: Li,
name: Yao,
name: Haiman,
name: Cochran,
name: Cheng,
name: Boston,
name: Graff,
name: Wilkens,
name: Schreiner,
name: Pankow,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Central adiposity measures such as waist circumference (WC) and waist-to-hip ratio (WHR) are associated with cardiometabolic disorders independently of BMI and are gaining clinically utility. Several studies report genetic variants associated with central adiposity, but most utilize only European ancestry populations. Understanding whether the genetic associations discovered among mainly European descendants are shared with African ancestry populations will help elucidate the biological underpinnings of abdominal fat deposition.
Wormhole geometries in fourth-order conformal Weyl gravity
Creators: name: Varieschi, Gabriele U.
name: Ault, Kellie L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Popular Physics (physics.pop-ph)
subject: FOS: Physical sciences

description: We present an analysis of the classic wormhole geometries based on conformal Weyl gravity, rather than standard general relativity. The main characteristics of the resulting traversable wormholes remain the same as in the seminal study by Morris and Thorne, namely, that effective super-luminal motion is a viable consequence of the metric. Improving on previous work on the subject, we show that for particular choices of the shape and redshift functions the wormhole metric in the context of conformal gravity does not violate the main energy conditions at or near the wormhole throat. Some exotic matter might still be needed at the junction between our solutions and flat spacetime, but we demonstrate that the averaged null energy condition (as evaluated along radial null geodesics) is satisfied for a particular set of wormhole geometries. Therefore, if fourth-order conformal Weyl gravity is a correct extension of general relativity, traversable wormholes might become a realistic solution for interstellar travel.
description: Minor changes and one equation added, 22 pages, including 4 figures, published in Int. J. Mod. Phys. D, Online Ready: 12 April 2016
Fast, label-free tracking of single viruses and weakly scattering nanoparticles in a nano-fluidic optical fiber
Creators: name: Faez, Sanli
name: Lahini, Yoav
name: Weidlich, Stefan
name: Garmann, Rees F.
name: Wondraczek, Katrin
name: Zeisberger, Matthias
name: Schmidt, Markus A.
name: Orrit, Michel
name: Manoharan, Vinothan N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: High-speed tracking of single particles is a gateway to understanding physical, chemical, and biological processes at the nanoscale. It is also a major experimental challenge, particularly for small, nanometer-scale particles. Although methods such as confocal or fluorescence microscopy offer both high spatial resolution and high signal-to-background ratios, the fluorescence emission lifetime limits the measurement speed, while photobleaching and thermal diffusion limit the duration of measurements. Here we present a tracking method based on elastic light scattering that enables long-duration measurements of nanoparticle dynamics at rates of thousands of frames per second. We contain the particles within a single-mode silica fiber containing a sub-wavelength, nano-fluidic channel and illuminate them using the fiber's strongly confined optical mode. The diffusing particles in this cylinderical geometry are continuously illuminated inside the collection focal plane. We show that the method can track unlabeled dielectric particles as small as 20 nm as well as individual cowpea chlorotic mottle virus (CCMV) virions - 4.6 megadaltons in size - at rates of over 2 kHz for durations of tens of seconds. Our setup is easily incorporated into common optical microscopes and extends their detection range to nanometer-scale particles and macromolecules. The ease-of-use and performance of this technique support its potential for widespread applications in medical diagnostics and micro total analysis systems.
description: 12 pages, 4 figures, updated references
Increased risk of influenza among vaccinated adults who are obese
Creators: name: Green,
name: Hudgens,
name: Rebeles,
name: Schultz-Cherry,
name: Beck,
name: Neidich,
name: Karlsson,
name: Noah,
name: Chakladar,
name: Weir,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Influenza infects 5–15% of the global population each year, and obesity has been shown to be an independent risk factor for increased influenza-related complications including hospitalization and death. However, the risk of developing influenza or ILI in a vaccinated obese adult population has not been addressed.
Newborn insula gray matter volume is prospectively associated with early life adiposity gain
Creators: name: Wadhwa,
name: Entringer,
name: Cooper,
name: Potkin,
name: Buss,
name: Styner,
name: Kruggel,
name: Rasmussen,
name: Gilmore,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The importance of energy homeostasis brain circuitry in the context of obesity is well established, however, the developmental ontogeny of this circuitry in humans is currently unknown. Here, we investigate the prospective association between newborn gray matter (GM) volume in the insula, a key brain region underlying energy homeostasis, and change in percent body fat accrual over the first six months of postnatal life, an outcome that represents among the most reliable infant predictors of childhood obesity risk.
Isotropic Detectable X-ray Counterparts to Gravitational Waves from Neutron Star Binary Mergers
Creators: name: Kisaka, Shota
name: Ioka, Kunihito
name: Nakamura, Takashi
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Neutron star binary mergers are strong sources of gravitational waves (GWs). Promising electromagnetic counterparts are short gamma-ray bursts (GRBs) but the emission is highly collimated. We propose that the scattering of the long-lasting plateau emission in short GRBs by the merger ejecta produces nearly isotropic emission for $\sim 10^4$ s with flux $10^{-13}-10^{-10}$ erg cm$^{-2}$ s$^{-1}$ at 100 Mpc in X-ray. This is detectable by Swift XRT and wide field X-ray detectors such as ISS-Lobster, Einstein Probe, eROSITA and WF-MAXI, which are desired by the infrared and optical follow-ups to localize and measure the distance to the host galaxy. The scattered X-rays obtain linear polarization, which correlates with the jet direction, X-ray luminosity and GW polarizations. The activity of plateau emission is also a natural energy source of a macronova (or kilonova) detected in short GRB 130603B without the $r$-process radioactivity.
description: 5 pages, 3 figures. Accepted for publication in Astrophysical Journal Letters
Warm Gas in and Around Simulated Galaxy Clusters as Probed by Absorption Lines
Creators: name: Emerick, Andrew
name: Bryan, Greg
name: Putman, Mary E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Understanding gas flows into and out of the most massive dark matter structures in our Universe, galaxy clusters, is fundamental to understanding their evolution. Gas in clusters is well studied in the hot ($>$ 10$^{6}$ K) and cold ($
description: 21 pages; 14 figures; 2 tables. Accepted for publication in MNRAS
Effect of bis(hydroxymethyl) alkanoate curcuminoid derivative MTH-3 on cell cycle arrest, apoptotic and autophagic pathway in triple-negative breast adenocarcinoma MDA-MB-231 cells: An in vitro study
Creators: name: Lu, Chi-Cheng
name: Chiu, Yu-Jen
name: Chang, Ling-Chu
name: Tsao, Je-Wei
name: Yang, Jai-Sing
name: Kuo, Sheng-Chu
name: Lee, Kuo-Hsiung
name: Tsai, Fuu-Jen
name: Hsieh, Min-Tsang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Curcumin has been shown to exert potential antitumor activity in vitro and in vivo involved in multiple signaling pathways. However, the application of curcumin is still limited because of its poor hydrophilicity and low bio-availability. In the present study, we investigated the therapeutic effects of a novel and water soluble bis(hydroxymethyl) alkanoate curcuminoid derivative, MTH-3, on human breast adenocarcinoma MDA-MB-231 cells. This study investigated the effect of MTH-3 on cell viability, cell cycle and induction of autophagy and apoptosis in MDA-MB-231 cells. After 24-h treatment with MTH-3, a concentration-dependent decrease in MDA-MB-231 cell viability was observed, and the IC50 value was 5.37±1.22 μM. MTH-3 significantly triggered G2/M phase arrest and apoptosis in MDA-MB-231 cells. Within a 24-h treatment, MTH-3 decreased the CDK1 activity by decreasing CDK1 and cyclin B1 protein levels. MTH-3-induced apoptosis was further confirmed by morphological assessment and Annexin V/PI staining assay. Induction of apoptosis caused by MTH-3 was accompanied by an apparent increase of DR3, DR5 and FADD and, as well as a marked decrease of Bcl-2 and Bcl-xL protein expression. MTH-3 also decreased the protein levels of Ero1, PDI, PERK and calnexin, as well as increased the expression of IRE1α, CHOP and Bip that consequently led to ER stress and MDA-MB-231 cell apoptosis. In addition, MTH-3-treated cells were involved in the autophagic process and cleavage of LC3B was observed. MTH-3 enhanced the protein levels of LC3B, Atg5, Atg7, Atg12, p62 and Beclin-1 in MDA-MB-231 cells. Finally, DNA microarray was carried out to investigate the level changes of gene expression modulated by MTH-3 in MDA-MB-231 cells. Taken together, our results suggest that MTH-3 might be a novel therapeutic agent for the treatment of triple-negative breast cancer in the near future.
Host-mediated  Leishmania donovani  treatment using AR-12 encapsulated in acetalated dextran microparticles
Creators: name: Bachelder,
name: Collier,
name: Borteh,
name: Varikuti,
name: Ainslie,
name: Sataoskar,
name: Papenfuss,
name: Peine,
name: Gautam,
name: Oghumu,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Leishmaniasis is a disease caused by parasites of Leishmania sp., which effects nearly 12 million people worldwide and is associated with treatment complications due to widespread parasite resistance toward pathogen-directed therapeutics. The current treatments for visceral leishmaniasis (VL), the systemic form of the disease, involve pathogen-mediated drugs and have long treatment regimens, increasing the risk of forming resistant strains. One way to limit emergence of resistant pathogens is through the use of host-mediated therapeutics. The host-mediated therapeutic AR-12, which is FDA IND-approved for cancer treatment, has shown activity against a broad spectrum of intracellular pathogens; however, due to hydrophobicity and toxicity, it is difficult to reach therapeutic doses. We have formulated AR-12 into microparticles (AR-12/MPs) using the novel biodegradable polymer acetalated dextran (Ace-DEX) and used this formulation for the systemic treatment of VL. Treatment with AR-12/MPs significantly reduced liver, spleen, and bone marrow parasite loads in infected mice, while combinatorial therapies with amphotericin B had an even more significant effect. Overall, AR-12/MPs offer a unique, host-mediated therapy that could significantly reduce the emergence of drug resistance in the treatment of VL.
Wörterbuch der Melancholie, Stichwort: Überleben, uns selbst begründen
Creators: name: Thomas, Philipp
Publisher: name: Universität Tübingen
Year: 2018
Subjects: subject: Melancholie , Descartes, René , Nietzsche, Friedrich
subject: 100
subject: Selbstbegründung
subject: Ressentiment
subject: resentment
subject: Performativität
subject: Foucault, Michel
subject: performativity
subject: self-foundation
subject: Barthes, Roland

description: Eine Lebensform, welche Melancholie mit umfassen möchte, muss sich selbst begründen, denn Melancholie gilt üblicherweise als Mangel. Dabei kommen drei klassische Formen der Selbstbegründung nicht in Frage: die Selbstbegründung über die Selbsteinschreibung in ein (ideologisches) big picture, die nach Paul Ricoeur eine 'narzisstische Versöhnung' genannt werden konnte, die Selbstbegründung des neuzeitlichen Subjekts (Descartes) und die Selbstbegründung durch Ressentiment (Nietzsche). Die gesuchte Form der Selbstbegründung einer melancholichschen Lebensform ist performativ, sie orientiert sich u.a. an Autoren wie Roland Barthes (Fragmente einer Sprache der Liebe) und Michel Foucault (Sorge um sich).
description: A life form which comprises melancholy needs a self-foundation since normally melancholy is considered as a defect. Three ways of self-foundation are not expedient: self-foundation by an ideological big picture (narcissistic reconciliation according to Paul Ricoeur), the self-foundation of the subject of modern philosophy (Descartes) and self-foundation by resentment (Nietzsche). The way of self-foundation which is advocated in this text is performative and follows authors like Roland Barthes (A Lover's Discourse: Fragments) and Michel Foucault (Le Souci de soi).
title: Wittenberger Matrikel ; 6
title: Album Academiae Vitebergensis
titleType: AlternativeTitle
title: Wittenberger Matrikel
titleType: AlternativeTitle
Creators: name: Universität Wittenberg
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1645
Subjects: subject: Wittenberg
subject: 090

description: f. 2r: Schmuckblatt für Iohannes Hulsemanus; unten: Ansicht des Hofes des Wittenberger Fridericianums mit Brunnen; f. 5r: Bildnis von Christophorus Wacke; f. 20r: Bildnis von Andreas Sennert, oben: Turmbau zu Babel, unten: Ausgießung des Heiligen Geistes; links der mittigen Schrifttafel: Moseh und Ezra, rechts: Cadmus, Evander; Carol(us) M(agnus); f. 58r: Bildnis von Iohannes Meisnerus Torg(ensis); unten: thronender Kaiser mit den Kurfürsten; f. 72: Bildnis von Augustus Buchnerus; links oben Wappen; f. 87r: Bildnis von Conradus Victor Schneider; f. 134r: Bildnis von Caspar Zieglerus Lipsensis; f. 148: Bildnis von Christian Klengel; f. 176: Portätkupferstich von Iohannes Meisner, 1667, F.C. Höckner et Christian Rombstedt scul. eingefügt. Schmuckleiste auf folio 231. Schmuckbuchstaben auf folio 157; 182; 224; 227; 229; 231.
A constant conversation: tuning into and harmonizing the needs and priorities of the body and mind
Creators: name: Chen, Annie T.
name: Carriere, Rachel
name: Kaplan, Samantha J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Purpose: Individuals rely upon many types of information to manage an illness, including information provided by their own bodies. This study investigated how people tune into and manage the flow of information from their bodies to manage their health. Method: We developed a platform for participants to share and collaboratively reflect on how they engaged in this dialogic process, in which participants contributed to a discussion on topics relating to body listening and body awareness. Though the study was open to anyone interested in or wanting to contribute to knowledge on “body listening,” the social media recruitment focused on chronic conditions requiring self-care and having overlapping symptomatology, with chronic pain as the primary characteristic. A qualitative analysis method based on grounded theory was used to analyse the data. Results: Six main themes emerged: learning the language, recognizing and heeding limits, experiencing emotional fatigue and despair, regulating the channel, moving from conflict to communication, and settling into an uneasy acceptance. Conclusion: The monitoring and filtering of information from one’s body, and the appeasement of conflicting demands and voices, is difficult work. Knowledge of this process can be used in patient education and in the development of tools to support body listening.
Patterns of Local-Regional Management Following Neoadjuvant Chemotherapy in Breast Cancer: Results From ACOSOG Z1071 (Alliance)
Creators: name: McCall, Linda M.
name: Buchholz, Thomas A.
name: Haffty, Bruce G.
name: Jagsi, Reshma
name: McLaughlin, Sarah
name: Ballman, Karla V.
name: Boughey, Judy C.
name: Ollila, David W.
name: Hunt, Kelly K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: AXXXXX ZXXXX was a prospective trial evaluating the false negative rate of sentinel node (SLN) surgery after neoadjuvant chemotherapy (NAC) in breast cancer patients with initial node-positive disease. Radiation therapy (RT) decisions were at the discretion of treating physicians, providing an opportunity to evaluate variability in practice patterns following NAC.
title: Wittenberger Matrikel ; 7
title: Album Academiae Vitebergensis
titleType: AlternativeTitle
title: Wittenberger Matrikel
titleType: AlternativeTitle
Creators: name: Universität Wittenberg
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1675
Subjects: subject: Wittenberg
subject: 090

description: f. 15r: Wappen von Werner Theodor Martini; f. 113r: Bildnis von Michael Sennert; f. 117v: Insignia Schato-Sennertia; f. 118: eingefügter Porträtkupferstich von Andreas Sennert, Michael Fennitzer sculpsit; f. 148v: Wappen von Caspar Heinrich Horn; f. 156v: Wappen von Georgius Francus Naumburgensis.
title: Wittenberger Matrikel ; 4
title: Album Academiae Vitebergensis
titleType: AlternativeTitle
title: Wittenberger Matrikel
titleType: AlternativeTitle
Creators: name: Universität Wittenberg
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1587
Subjects: subject: Wittenberg
subject: 090

description: f. 2r: Wappen von Iohannes Zangerus; f. 23v: Wappen von Franciscus Banfi Losonci; f. 32r: Wappen von Eberhartus a Weyhe; f. 47r: Wappen von Wighardus Liber Baro a Promnitz; f. 62r: Wappen von Ioannes Grunius Noribergensis; f. 75: Wappen von Petrus Heigius Stralsundenis Pomeranus; f. 100r: Wappen von Ludovicus Person Witebergensis; f. 109r: Wappen von Iohannes Haigius Witebergensis ; f. 169r: Wappen von Augustus Dux Saxoniae; f. 209r: Wappen von Augustus Dux Saxoniae im Schmuckrahmen, unten mit einer Ansicht von Wittenberg; f. 212r: Wappen von Melchior Joestelius Dresdensis; f. 222r: Wappen von Bartholomaeus Reusner Vratislaviensis auf einer Schmuckseite; f. 245r: Wappen von Lucas Beekmannus Hamburgensis, unten auf einer Schmuckseite. Schmuckseiten auf folio 67; 73; 81; 94; 99; 116; 121, 126; 131; 140; 150; 156; 162; 170; 222; 245. Schmuckleisten auf folio 3; 10; 16; 24; 28; 37; 42; 46; 53; 59; 62; 88; 106; 110; 136; 172; 176; 181; 186; 190; 193; 197; 201; 205; 210; 217; 223; 228; 246. Schmuckbuchstaben auf folio 106; 199
title: Wittenberger Matrikel ; 3
title: Album Academiae Vitebergensis
titleType: AlternativeTitle
title: Wittenberger Matrikel
titleType: AlternativeTitle
Creators: name: Universität Wittenberg
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1565
Subjects: subject: Wittenberg
subject: 090

description: Vorderspiegel: Forma promissionis; f. 36v: Wappen von Caspar Peucer; f. 52v: Wappen von Bohuslaw Ioachim Baro a Lobcowitz et Hassenstein Dominus in Litzkow; f. 61v: Wappen von Ioachim a Beust; f. 68v: Wappen von Stephanus Gans Baro in Püdlitz; f. 89: Wappen von Micael Slavatas, Dominus a Chlum et Cossenberg; f. 106: Wappen von Iohannis Comes Hardecij, Glocij et Machlandiae, Baro Startenberg, Dominus Crucingensis etc.; f. 114v: Wappen von Henricus Mollerus; f. 146r: Wappen von Ioannes Cyriacus, liberus Baro in Polhaim et Wartenburg; f. 164v: Wappen von Andreas Wolfgangus Baro Austriacus et Polhaim; f. 207v: Wappen von Baro Ladislaus a Schleinitz; f. 249v: Wappen von Ernestus Dux Brunsvicensis et Lunaeburgensis; f. 256r. Wappen von Augustus Dux Brunsvicensis et Lunaeburgensis.Schmuckleisten auf folio 46; 69; 90; 95; 107; 115; 158; 179; 240/242; 245; 249; 255; 262; 269; 274; 282.
Fast Estimators for Redshift-Space Clustering
Creators: name: Scoccimarro, Roman
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Redshift-space distortions in galaxy surveys happen along the radial direction, breaking statistical translation invariance. We construct estimators for radial distortions that, using only Fast Fourier Transforms (FFTs) of the overdensity field multipoles for a given survey geometry, compute the power spectrum monopole, quadrupole and hexadecapole, and generalize such estimators to the bispectrum. Using realistic mock catalogs we compare the signal to noise of two estimators for the power spectrum hexadecapole that require different number of FFTs and measure the bispectrum monopole, quadrupole and hexadecapole. The resulting algorithm is very efficient, e.g. for the BOSS survey requires about three minutes for $\ell=0,2,4$ power spectra for scales up to $k=0.3~h/$Mpc and about fifteen additional minutes for $\ell=0,2,4$ bispectra for all scales and triangle shapes up to $k=0.2~h/$Mpc on a single core. The speed of these estimators is essential as it makes possible to compute covariance matrices from large number of realizations of mock catalogs with realistic survey characteristics, and paves the way for improved constrains of gravity on cosmological scales, inflation and galaxy bias.
description: 9 pages, 3 figures
Set mappings on 4-tuples
Creators: name: Mohsenipour, Shahram
name: Shelah, Saharon
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics

description: In this paper we study set mappings on 4-tuples. We continue a previous work of Komjath and Shelah by getting new finite bounds on the size of free sets in a generic extension. This is obtained by an entirely different forcing construction. Moreover we prove a ZFC result for set mappings on 4-tuples and also as another application of our forcing construction we give a consistency result for set mappings on triples.
description: Accepted to be published in Notre Dame Journal of Formal Logic
Simple Factors Associated With Radiation-Induced Lung Toxicity After Stereotactic Body Radiation Therapy of the Thorax: A Pooled Analysis of 88 Studies
Creators: name: Das, Shiva
name: Yorke, Ellen D.
name: Rimner, Andreas
name: Li, Ling
name: Milano, Michael T.
name: Campbell, Jeffrey
name: Jackson, Andrew
name: Miften, Moyed
name: Grimm, Jimm
name: Kavanagh, Brian D.
name: Zhao, Jing
name: Xue, Jinyu
name: Spring Kong, Feng-Ming
name: Li, X. Allen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: To study the risk factors for radiation-induced lung toxicity (RILT) after stereotactic body radiotherapy (SBRT) of the thorax.
The importance of absence in the present: practices of remembrance and the contestation of absences
Creators: name: Meier, Lars
name: Frers, Lars
name: Sigvardsdotter, Erika
Publisher: name: Technische Universität Berlin
Year: 2013
Subjects: subject: 910 Geografie, Reisen
subject: 390 Bräuche, Etikette, Folklore
subject: absence
subject: remembrance
subject: present

description: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
description: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
description: What is missing, where and for whom? And how does that which is absent relate to the things and people that are present? This special issue of cultural geographies demonstrates the relevance of absence in its social and spatial dimensions. By focusing on that which does not claim physical presence, that which is missing or hiding, this issue demonstrates how an in-depth examination of the phenomenon of absence can provide stimulating vectors of analysis.
Formation of a carcinogenic aromatic amine from an azo dye by human skin bacteria in vitro
Creators: name: Platzek, T.
name: Lang, C.
name: Grohmann, G.
name: Gi, U.-S.
name: Baltes, W.
Publisher: name: Technische Universität Berlin
Year: 1999
Subjects: subject: 610 Medizin und Gesundheit
subject: azo dyes
subject: skin bacteria
subject: metabolism

description: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
description: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
description: Azo dyes represent the major class of dyestuffs. They are metabolised to the corresponding amines by liver enzymes and the intestinal microflora following incorporation by both experimental animals and humans. For safety evaluation of the dermal exposure of consumers to azo dyes from wearing coloured textiles, a possible cleavage of azo dyes by the skin microflora should be considered since, in contrast to many dyes, aromatic amines are easily absorbed by the skin. A method for measuring the ability of human skin flora to reduce azo dyes was established. In a standard experiment, 361011 cells of a culture of Staphylococcus aureus wereincubatedinsyntheticsweat (pH 6.8, final volume 20 mL) at 288C for 24 h with Direct Blue 14 (C.I. 23850, DB 14). The reaction products were extracted and analysed using HPLC. The reduction product o-tolidine (3,3'-dimethylbenzidine, OT) could indeed be detected showing that the strain used was able to metabolise DB 14 to the corresponding aromatic amine. In addition to OT, two further metabolites of DB 14 were detected. Using mass spectrometry they were identified as 3,3'-dimethyl-4-amino-4'-hydroxybiphenyl and 3,3'-di methyl-4-aminobiphenyl. The ability to cleave azo dyes seems to be widely distributed among human skin bacteria, as, under these in vitro conditions, bacteria isolated from healthy human skin and human skin bacteria from strain collections also exhibited azo reductase activity. Further studies are in progress in order to include additional azo dyes and coloured textiles. At the moment, the meaning of the results with regard to consumer health cannot be finally assessed.
Magnetic phase transitions of spin-1 ultracold bosons in a cubic optical lattice
Creators: name: Li, Yongqiang
name: He, Liang
name: Hofstetter, Walter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We investigate strongly correlated spin-1 ultracold bosons with antiferromagnetic interactions in a cubic optical lattice, based on bosonic dynamical mean-field theory. Rich phase diagrams of the system are mapped out at both zero and finite temperature, and in particular the existence of a spin-singlet condensate is established. Interestingly, at finite temperature, we find that the superfluid can be heated into a Mott insulator with even (odd) filling via a first- (second-) order phase transition, analogous to the Pomeranchuk effect in $^{3}$He. Moreover, for typical experimental setups, we estimate the critical temperatures for different ordered phases and our results suggest that direct experimental observation of these phases is promising.
description: 5 pages, 3 figures
The American Society for Radiation Oncology's 2015 Core Physics Curriculum for Radiation Oncology Residents
Creators: name: Xiao, Ying
name: Prisciandaro, Joann
name: Ritter, Tim
name: Smith, Chadd
name: Schreiber, Eric
name: Chetty, Indrin J.
name: Nalichowski, Adrian
name: Howell, Rebecca M.
name: McDermott, Patrick
name: Dominello, Michael M.
name: Doemer, Anthony
name: Shafman, Timothy
name: Sutlief, Steven
name: Dieterich, Sonja
name: Chen, Zhe
name: Burmeister, Jay
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: 1 The American Society for Radiation Oncology’s 2015 Core Physics Curriculum 2 for Radiation Oncology Residents Jay Burmeister, PhD Department of Oncology, Karmanos Cancer Center / Wayne State University, Detroit, Michigan 48201, USA Zhe Chen, PhD Department of Therapeutic Radiology, Yale University, New Haven, Connecticut 06510, USA Indrin J. Chetty, PhD Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48201, USA Sonja Dieterich, PhD Department of Radiation Oncology, University of California – Davis, Sacramento, California 95618, USA Anthony Doemer, MS Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48201, USA Michael M. Dominello, DO Department of Oncology, Karmanos Cancer Center / Wayne State University, Detroit, Michigan 48201, USA Rebecca M. Howell, PhD Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA Geoffrey Ibbott, PhD Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA Patrick McDermott, PhD Department of Radiation Oncology, Beaumont Health, Troy, Michigan 48098, USA Adrian Nalichowski, MS Karmanos Cancer Center, Detroit, Michigan 48201, USA Joann Prisciandaro, PhD Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA Tim Ritter, PhD VA Ann Arbor Healthcare and the University of Michigan, Ann Arbor, Michigan 48105, USA Chadd Smith, PhD Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48201, USA Eric Schreiber, PhD Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina 27599, USA Timothy Shafman, MD 21 st Century Oncology, Fort Myers, Florida 33907, USA Steven Sutlief, PhD Department of Radiation Oncology, University of California – San Diego, La Jolla, California 92093, USA Ying Xiao, PhD Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA Corresponding Author: Jay Burmeister, PhD Wayne State University School of Medicine Karmanos Cancer Center Detroit, MI 48201 Email: burmeist@karmanos.org Running Title: The ASTRO 2015 Resident Physics Curriculum
title: Wittenberger Matrikel ; 5
title: Album Academiae Vitebergensis
titleType: AlternativeTitle
title: Wittenberger Matrikel
titleType: AlternativeTitle
Creators: name: Universität Wittenberg
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1610
Subjects: subject: Wittenberg
subject: 090

description: f. 13r: Wappen von Wolfgangius Hirschbachius; f. 22r: Wappen von Iacobus Martini Halberstadiensis auf Schmuckseite; f. 31: Wappen von Erasmus Unruh Torgensis auf Schmuckseite; f. 48: Schmuckseite für Balthasar Meisnerus Dresdensis; f. 62r: Wappen von Comes Emericus Thurzo de Bettlenffalwa auf Schmuckseite; f. 65r: Wappen von Comes Emericus Thurzo de Bettlenffalwa auf Schmuckseite; f. 87r: Schmuckseite für Daniel Sennertus Vratislaviensis; f. 197r: Schmuckseite für Daniel Sennertus Vratislaviensis; f. 238: Schmuckseite für Daniel Sennertus Vratisl.(aviensis); f. 252: Bildnis von Iohannes Hulsemannus; f. 258: Wappen von Marcus Bantzerus Augustano-Vindelicorum. Schmuckseiten auf folio 18; 22; 31; 48; 62; 65; 87, 145; 197; 238; 252; 258. Schmuckleisten auf folio 14; 17; 94; 265; 279. Schmuckbuchstaben auf folio 72; 91. Vignetten auf folio 96v; 97; 266.
Search for dark matter produced in association with a Higgs boson decaying to two bottom quarks in $pp$ collisions at $\sqrt{s} = 8$ TeV with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: This article reports on a search for dark matter pair production in association with a Higgs boson decaying to a pair of bottom quarks, using data from $20.3 fb^{-1}$ of $pp$ collisions at a center-of-mass energy of 8 TeV collected by the ATLAS detector at the LHC. The decay of the Higgs boson is reconstructed as a high-momentum $b\bar{b}$ system with either a pair of small-radius jets, or a single large-radius jet with substructure. The observed data are found to be consistent with the expected Standard Model backgrounds. Model-independent upper limits are placed on the visible cross-sections for events with a Higgs boson decaying into $b\bar{b}$ and large missing transverse momentum with thresholds ranging from 150 GeV to 400 GeV. Results are interpreted using a simplified model with a $Z^\prime$ gauge boson decaying into different Higgs bosons predicted in a two-Higgs-doublet model, of which the heavy pseudoscalar Higgs decays into a pair of dark matter particles. Exclusion limits are also presented for the mass scales of various effective field theory operators that describe the interaction between dark matter particles and the Higgs boson.
description: 30 pages plus author list (47 pages total), 7 figures, 6 tables, submitted to Phys.Rev.D. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2014-20