cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
AKSZ constructions for topological membranes on $G_2$-manifolds
Creators: name: Kokenyesi, Zoltan
name: Sinkovics, Annamaria
name: Szabo, Richard J.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Quantum Algebra (math.QA)
subject: Symplectic Geometry (math.SG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider AKSZ constructions of BV actions for closed topological membranes, and their dimensional reductions to topological string sigma-models. Two inequivalent AKSZ constructions for topological membranes on $G_2$-manifolds are proposed, in each of which the two existing topological membrane theories appear as different gauge fixed versions. Their dimensional reductions give new AKSZ constructions for the topological A-model, which on further dimensional reduction gives an AKSZ formulation of supersymmetric quantum mechanics. We show that the two AKSZ membrane models originate through worldvolume dimensional reduction of a single AKSZ threebrane theory, which gives the standard 2-Courant bracket as the underlying derived bracket. Double dimensional reduction of the twisted topological threebrane theory on a circle yields the standard Courant sigma-model for string theory with NS-NS flux.
description: 36 pages; Final version to be published in Fortschritte der Physik
Large Scale Structure Effects on the Gravitational Lens Image Positions and Time Delay
Creators: name: Seljak, Uros
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We compute the fluctuations in gravitational lens image positions and time delay caused by large scale structure correlations. We show that these fluctuations can be expressed as a simple integral over the density power spectrum. Using the {\sl COBE} normalization we find that positions of objects at cosmological distances are expected to deviate from their true positions by a few arcminutes. These deflections are not directly observable. The positions of the images relative to one another fluctuate by a few percent of the relative separation, implying that one does not expect multiple images to be produced by large scale structures. Nevertheless, the fluctuations are larger than the observational errors on the positions and affect reconstructions of the lens potential. The time delay fluctuations have a geometrical and a gravitational contribution. Both are much larger than the expected time delay from the primary lens, but partially cancel each other. We find that large scale structure weakly affects the time delay and time delay measurements can be used as a probe of the distance scale in the universe.
description: 20 pages, AAS Latex, ApJ, in press 1994, preprint MIT-CSR-94-05
L’occhio e la pietà. Forme della conoscenza e dell’interpretazione ne «La giornata d’uno scrutatore» di Calvino
Creators: name: Russo, Pietro
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Vista
Distanza
Umano
Confine
Vision
Distance
Humankind
Border

description: Dall’esordio romanzesco de “Il sentiero dei nidi di ragno” ai tentativi parossistici di descrizione visiva di “Palomar”, passando per lo sguardo distante del “Barone rampante” e la pulsione-ossessione fotografica de “L’avventura di un fotografo”, l’opera di Italo Calvino è attraversata da una costante attenzione per le forme e le modalità della visione. Variamente declinato, questa tema implica da una parte un ampliamento delle potenzialità conoscitive della scrittura e, dall’altra, un fruttuoso sconfinamento nei territori delle arti visive (cinema, fotografia e pittura). In questo quadro, “La giornata d’uno scrutatore”, il racconto del 1963 che segna una svolta cruciale nella narrativa dello scrittore ligure, condensa il senso nonché i limiti della poetica calviniana dello sguardo. Qui la metafora ottico-visiva, eletta a vera protagonista della vicenda, si trova a fronteggiare la crisi storica ed esistenziale conseguente alla «sfida al labirinto». Sarà assumendo un altro ‘punto di vista’, quello dei ricoverati del Cottolengo, che Calvino, dietro lo schermo letterario di Amerigo Ormea, riuscirà a trovare, sebbene provvisoriamente, l’uscita da tale labirinto.
description: From the novelistic debut with ‘Il sentiero dei nidi di ragno’ to the paroxysmal attempts at visual description in ‘Palomar’, through the distant gaze of the ‘Barone rampante’ and the photographic drive-obsession of ‘L’avventura di un fotografo’, Italo Calvino’s work is traversed by a constant attention to forms and modalities of vision. Variously declined, this topic implies, on one hand, an amplification of the cognitive potentialities of writing and, on the other hand, a fruitful encroachment within the territory of visual arts (cimena, photography, and painting). In this framework, ‘La giornata d’uno scrutatore’ - a 1963 short story that marks a crucial turn in the writing of the Ligurian writer – condenses the sense if not the limits of Calvino’s poetics of the gaze. Here, the optical-visual metaphor, elected as the true protagonist of the story, addresses the historical and existential crisis consequent to the “chellenge of the labyrinth.” It is only by assuming another “point of view”, the one of those admitted at Cottolengo, that Calvino, behind the literary screen of Amerigo Ormea, succeds at finding, even if provisionally, an exit from this labyrinth.
Superfluid and Mott Insulator phases of one-dimensional Bose-Fermi mixtures
Creators: name: Zujev, A.
name: Baldwin, A.
name: Scalettar, R. T.
name: Rousseau, V. G.
name: Denteneer, P. J. H.
name: Rigol, M.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the ground state phases of Bose-Fermi mixtures in one-dimensional optical lattices with quantum Monte Carlo simulations using the Canonical Worm algorithm. Depending on the filling of bosons and fermions, and the on-site intra- and inter-species interaction, different kinds of incompressible and superfluid phases appear. On the compressible side, correlations between bosons and fermions can lead to a distinctive behavior of the bosonic superfluid density and the fermionic stiffness, as well as of the equal-time Green functions, which allow one to identify regions where the two species exhibit anticorrelated flow. We present here complete phase diagrams for these systems at different fillings and as a function of the interaction parameters.
description: 8 pages, 12 figures
Charge-density-wave phase, mottness and ferromagnetism in monolayer $1T$-NbSe$_2$
Creators: name: Pasquier, Diego
name: Yazyev, Oleg V.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The recently investigated $1T$-polymorph of monolayer NbSe$_2$ revealed an insulating behaviour suggesting a star-of-David phase with $\sqrt{13}\,\times\sqrt{13}$ periodicity associated with a Mott insulator, reminiscent of $1T$-TaS$_2$. In this work, we examine this novel two-dimensional material from first principles. We find an instability towards the formation of an incommensurate charge-density-wave (CDW) and establish the star-of-David phase as the most stable commensurate CDW. The mottness in the star-of-David phase is confirmed and studied at various levels of theory: the spin-polarized generalized gradient approximation (GGA) and its extension involving the on-site Coulomb repulsion (GGA+$U$), as well as the dynamical mean-field theory (DMFT). Finally, we estimate Heisenberg exchange couplings in this material and find a weak nearest-neighbour ferromagnetic coupling, at odds with most Mott insulators. We point out the close resemblance between this star-of-David phase and flat-band ferromagnetism models.
«Forse la realtà è fantastica di per sé» Scrittura e finzione nell’opera narrativa di Tabucchi: (“Donna di Porto Pim” e “Notturno indiano”)
Creators: name: Proserpi, Natalia
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Antonio Tabucchi
Donna di Porto Pim
Notturno indiano
Metafinzione postmoderna
Ambiguità realtà finzione
Postmodern metafiction
Reality fiction ambiguity

description: L’opera narrativa di Antonio Tabucchi, in un’epoca in cui il mondo appare sempre più complesso e sfaccettato, si interroga sulla scrittura e sul suo rapporto ambiguo con la realtà. In essa l’autore, attraverso svariati riferimenti alla pratica letteraria – personaggi-scrittori, strutture metanarrative, commenti sulla scrittura e in genere accorgimenti metafinzionali –, riflette sulle effettive capacità della letteratura di arrivare a comprendere e raffigurare il reale, così come più in generale sui limiti e le possibilità della scrittura in epoca postmoderna. In questo contributo, al fine di mettere in luce le varie direzioni assunte da tale riflessione, i diversi riferimenti menzionati sono stati suddivisi in quattro categorie, tutte rientranti nel panorama della metafinzione postmoderna. Prendendo in considerazione due opere degli anni ’80 – “Donna di Porto Pim” e “Notturno indiano” –, questo saggio vuole mostrare come i numerosi riferimenti alla pratica letteraria siano funzionali a esprimere un ragionamento esteso e articolato sulla scrittura, la quale deve trovare nuove possibilità narrative capaci di far fronte a una realtà equivoca e multiforme sempre meno afferrabile.
description: Antonio Tabucchi’s narrative work, at a time when the world is becoming more and more complex and multifaceted, wonders about writing and its ambiguous relationship with reality. Through several allusions to the literary practice – such as writers-figures, metanarratives structures, comments on writing, and in general metafictional expedients –the author investigates the actual abilities of literature to understand portray reality, as well as the limits and the possibilities of writing in the postmodern period. In the present study, to highlight the different directions of author’s investiogation, the various allusions have been grouped into four categories, all of within the panorama of postmodern metafiction. Taking into account twoworks from 80s – ‘Donna in Porto Pim and Indian Nocturne -, this article aims to show how the allusions to the literary practice can express a wide and complex reasoning on writing; a writing that needs to find new narrative possibilities, to be able to face an equivocal and multiform reality that is less and less comprehensible.
Modelling Formation of Online Temporal Communities
Creators: name: Inuwa-Dutse, Isa
Publisher: name: arXiv
Year: 2018
Subjects: subject: Social and Information Networks (cs.SI)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Contemporary social media networks can be viewed as a break to the early two-step flow model in which influential individuals act as intermediaries between the media and the public for information diffusion. Today's social media platforms enable users to both generate and consume online contents. Users continuously engage and disengage in discussions with varying degrees of interaction leading to formation of distinct online communities. Such communities are often formed at high-level either based on metadata, such as hashtags on Twitter, or popular content triggered by few influential users. These online communities often do not reflect true connectivity and lack the cohesiveness of traditional communities. In this study, we investigate real-time formation of temporal communities on Twitter. We aim at defining both high and low levels connections and to reveal the magnitude of clustering cohesion on temporal basis. Inspired by a real-life event center sitting arrangement scenario, the proposed method aims to cluster users into distinct and cohesive online temporal communities. Membership to a community relies on intrinsic tweet properties to define similarity as the basis for interaction networks. The proposed method can be useful for local event monitoring and clique-based marketing among other applications.
description: 5 pages, 7 figures
Stellar population of the superbubble N206 in the LMC II. Parameters of the OB and WR stars, and the total massive star feedback
Creators: name: Ramachandran, Varsha
name: Hamann, W. -R.
name: Hainich, R.
name: Oskinova, L. M.
name: Shenar, T.
name: Sander, A. A. C.
name: Todt, H.
name: Gallagher, J. S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Clusters or associations of early-type stars are often associated with a 'superbubble' of hot gas. The formation of such superbubbles is caused by the feedback from massive stars. The complex N206 in the Large Magellanic Cloud exhibits a superbubble and a rich massive star population. We observed these massive stars using the FLAMES multi-object spectrograph at ESO-VLT. Available UV spectra from HST, IUE, and FUSE are also used. The spectral analysis is performed with Potsdam Wolf-Rayet (PoWR) model atmospheres. We present the stellar and wind parameters of the OB stars and the two WR binaries in the N206 complex. Twelve percent of the sample show Oe/Be type emission lines, although most of them appear to rotate far below critical. We found eight runaway stars based on their radial velocity. The wind-momentum luminosity relation of our OB sample is consistent with the expectations. The HRD of the OB stars reveals a large age spread (1-30 Myr), suggesting different episodes of star formation in the complex. The youngest stars are concentrated in the inner part of the complex, while the older OB stars are scattered over outer regions. We derived the present day mass function for the entire N206 complex as well as for the cluster NGC2018. Three very massive Of stars are found to dominate the feedback among 164 OB stars in the sample. The two WR winds alone release about as much mechanical luminosity as the whole OB star sample. The cumulative mechanical feedback from all massive stellar winds is comparable to the combined mechanical energy of the supernova explosions that likely occurred in the complex. Accounting also for the WR wind and supernovae, the mechanical input over the last five Myr is ~$2.3\times10^{52}$ erg, which exceeds the current energy content of the complex by more than a factor of five. The morphology of the complex suggests a leakage of hot gas from the superbubble.
description: Accepted for publication in A&A
Trespassing the defensive lines cardiovascular infection
Creators: name: McDonnell, Cormac J.
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Sepsis is one of the major causes of mortality in critically ill patients worldwide. The bloodstream is a normally sterile environment but upon infection a dysregulated and deleterious inflammatory response can be induced. The damage from the inflammatory response leads to organ failure and ultimately death. Routinely sepsis is associated with the bacteria Staphylococcus aureus. While the pathophysiology of severe sepsis is not well defined it is accepted that sepsis-associated mortality is related to the host response which involves a multitude of cell types, inflammatory mediators and coagulation factors. The endothelium is a major target of sepsis-induced events as it is among the first cells in the body to come into contact with circulating bacteria. This aim of this thesis was to investigate the role partaken by endothelium in mediating the sepsis phenotype and focus on the potential value of the endothelium as a target for sepsis therapy. Previous studies have identified several mechanisms that S. aureus uses to bind to endothelial cells using a range of different models. Cognisant of ensuring that we are using as close to a physiological model of infection as possible, we developed a model using conditions that closely mimic conditions experienced in the vasculature. Using this model we identified a previously undescribed interaction between S. aureus and human endothelial cells. We identified that S. aureus clumping factor A binds plasma fibrinogen and crosslinks to Human Endothelial cell integrin αVβ3. This interaction results in the generation of an intracellular signal that leads to apoptosis, loss of cell numbers and increased vascular permeability, all clinical signs of the sepsis phenotype in humans. Using a strain deficient in expression of clumping factor A or blocking the endothelial cell integrin αVβ3 using a c(RGDfV) peptide significantly reduced the binding interaction and the associated dysfunctional effects apoptosis, loss of cell recovery and increased vascular permeability. Our results suggest that using the c(RGDfV) (currently developed as EMD121974) may be useful in the early treatment of sepsis.
La costruzione del personaggio Serafino nei «Quaderni» di Pirandello
Creators: name: Giulio, Rosa
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Pirandello
Serafino
Strategia compositiva
Compositional strategy

description: Dei “Quaderni di Serafino Gubbio operatore”, con un procedimento attento alla sola struttura diegetica, si analizza la strategia compositiva nella costruzione del testo e del personaggio, che consente a Pirandello di riproporre, se pure in maniera apparentemente frammentata e casuale, temi e motivi ricorrenti. Finalità dell’indagine è illuminare la vigile consapevolezza cronologica e spaziale dell’autore, attuata con continuità soprattutto nell’abile uso pendolare dei tempi e nella disarticolata collocazione dei luoghi del romanzo, e valorizzare il ricco apparato delle annotazioni, non marginalizzate ma chiamate a ruolo speculare, a continui raffronti con scritture di affini esperienze narrative.
description: This essay analyses ‘Quaderni di Serafino Gubbio operatore’ payng attention to its diegetic structure. More specifically, the study focuses on the constituent strategy of the text and character which allows Pirandello to reuse – though apparently in a frafmentary and random way – cclic themes and motifs. The aim is to demostrate the conscious chronological and spatial awareness of the author; such an awareness is showed by the skilled pendular use of tenses and the disarticulated positioning of places in the novel. Thus, the paper will also anhance the rich apparatus of annotations, unmarginalized and specular, as regards similar narrative experiences.
Additional file 4: of Whole genome sequencing and identification of Bacillus endophyticus and B. anthracis isolated from anthrax outbreaks in South Africa
Creators: name: Kgaugelo Lekota
name: Bezuidt, Oliver
name: Mafofo, Joseph
name: Rees, Jasper
name: Farai Muchadeyi
name: Madoroba, Evelyn
name: Heerden, Henriette Van
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Table S1. Plasmid comparison of the four sequenced Bacillus endophyticus strains (3618_1C, 3631_9D, 3631_10C, 3617_2C) with B. endophyticus Hbe603 strain. (DOC 18 kb)
title: ADCO, Ordre cistercien : comptes (1403-1423) (11 H 1161), f. 00253
Creators: name: de la Côte-d'Or, Archives départementales
name: CBMA/CG21/F.PETOT/2019
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes
subject: LaMOP

description: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161), f. 00253, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
Introduction to moduli, l-adic representations and the Regular Version of the Inverse Galois Problem
Creators: name: Fried, Michael D.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: Sect 1 introduces Nielsen classes attached to (G,C), where C is r conjugacy classes in a finite group G, and a braid action on them. These give reduced Hurwitz spaces, denoted H(G,C)^rd. The section concludes with a braid formula for the genus of these spaces when r = 4. If there is at least one prime l for which G is divisible by l, but has no Z/l quotient, then there is a canonical tower of reduced Hurwitz spaces over H(G,C)^rd, using the Universal Frattini cover, ~G, of G, and ~G_ab, its abelianized version. The towers are nonempty assuming C are l' classes satisfying a cohomological condition from a lift invariant. A M(odular)T(ower) is a projective sequence of components of the canonical tower. Sect 2 introduces the book [Fr18], which takes on generalizing Serre's O(pen)I(mage)T(heorem}, interpreted as the case when G is a dihedral group D_l and C is four repetitions of the involution conjugacy class. Serre's Theorem separated decomposition groups of projective sequences of points in the modular curve towers into two types: CM (complex multiplication) and GL_2. When r = 4, all MT levels are upper half-plane quotients ramified at 0 (of order 3), 1 (of order 2) and \infty (corresponding to the cusps). They are appropriate therefore to compare Serre's OIT with the cusps and decomposition group fibers. [Fr18] emphasizes new phenomena in cusps, and components, while still showing in high tower levels a valid comparison with modular curves. It also aims to show how MTs can expand the applications usual for modular curve towers, recognizing those problems directly interpret from the Inverse Galois Problem. The l-adic representations of the title come from the abelianized version of the Universal Frattini cover.
title: ADCO, Cartulaire de Cîteaux pour les possessions de Tontenant (c. 1504), Cart. 184 (11 H 987), 105 folios, f. 0136
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les possessions de Tontenant (c. 1504), Archives départementales de la Côte-d'Or, Cart. 184 (11 H 987), 105 folios, f. 0136, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Tontenant (c. 1504), Archives départementales de la Côte-d'Or, Cart. 184 (11 H 987), 105 folios, f. 0136, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: abbaye de Cîteaux
Equivalent Quantisations of (2+1)-Dimensional Gravity
Creators: name: Carlip, S.
name: Nelson, J. E.
Publisher: name: arXiv
Year: 1993
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: For spacetimes with the topology $\IR\!\times\!T^2$, the action of (2+1)-dimensional gravity with negative cosmological constant $\La$ is written uniquely in terms of the time-independent traces of holonomies around two intersecting noncontractible paths on $T^2$. The holonomy parameters are related to the moduli on slices of constant mean curvature by a time-dependent canonical transformation which introduces an effective Hamiltonian. The quantisation of the two classically equivalent formulations differs by terms of order $O(\hbar^3)$, negligible for small $|\La|$.
description: 7 pages, Plain Tex, DFTT 67/93, UCD-93-33
Il ritmo hip hop di Sanguineti: da “Rap” alle forme d’arte underground nella «Wunderkammer»
Creators: name: Tavella, Chiara
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Edoardo Sanguineti
Andrea Liberovici
Rap
Arte underground
Underground art

description: Spinto dall’interesse per la contaminazione intermediale, Sanguineti si è spesso avventurato nei territori della musica, approdando di volta in volta ai lidi più diversi: la sua attenzione negli anni ’90 viene attirata dal repertorio giovanile e dall’arte underground. Sulla base dei documenti conservati nella Wunderkammer si possono ora leggere le riflessioni contenute nell’articolo “Rap e poesia” e in numerose interviste, ricostruendo così la genesi di “Rap”, lo spettacolo poetico-musicale ideato nel 1996 in collaborazione con Andrea Liberovici, e provando a chiarire le ragioni linguistiche e militanti alla base dell’attenzione del poeta per l’hip hop.
description: Driven by the interest in intermedial contamination, Sanguineti has often ventured into the territories of music, arriving from time to time in different shores: in the 1990s, he becomes fond of the youth repertoire and the underground art. On the basis of the documents preserved in the ‘Wunderkammer’ it is now possibleto read the reflectionscontained in the article ‘Rap e poesia’ and in many interviews, thus retracing the genesis of ‘Rap’, the poetic-musical spectacle written in 1996 with Andrea Liberovici, and trying to clarify the linguistic and militant reasons behind the poet’s attention to hip hop.
Type 2 diabetes and breast cancer - the role of hyperinsulinaemia in breast cancer development and mortality
Creators: name: Gallagher, Emily Jane
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Obesity, type 2 diabetes and the metabolic syndrome are associated with an increased risk of developing breast cancer. In addition, these conditions are associated with more aggressive forms of breast cancer and greater breast cancer mortality. All three conditions are associated with insulin resistance and endogenous hyperinsulinemia. Breast cancers express the insulin receptor (IR), therefore we hypothesize that endogenous hyperinsulinaemia promotes breast cancer growth and metastases by acting directly on the IR on the tumour cells, and by causing epithelial to mesenchymal transition in the tumour. We found that hyperinsulinaemia led to increased growth and metastasis of both murine and human breast cancers in an animal model of hyperinsulinaemia. We found that the increase in tumour metastasis was associated with increased vimentin expression in the primary tumours. We found that silencing the IR reduced the growth of human breast cancer xenografts in the animals, associated with a decrease in vimentin expression. Silencing vimentin in breast cancer cells reduced their ability to invade in vitro and decreased their metastatic capabilities in the hyperinsulinaemic mice. Examining human breast cancer cell lines, we found that triple negative breast cancer cell lines had higher IR expression than oestrogen receptor positive breast cancer cell lines, and that the main isoform of the IR in both human breast cancer specimens and cell lines was the IR-A isoform. Higher levels of IR-A and lower levels of IR-B correlated with changes in the expression of splicing factors, SRSF3 and MBNL2 in both the breast cancer cell lines and the human breast cancer specimens. We found that none of the insulin analogues in clinical use increased tumour growth, but a mitogenic analogue AspB10 stimulated tumour growth by activating the IR. These data show that endogenous hyperinsulinaemia and IR signaling are important regulators of breast cancer growth and progression.
MOESM2 of Characterizing the effect of expression of an acetyl-CoA synthetase insensitive to acetylation on co-utilization of glucose and acetate in batch and continuous cultures of E. coli W
Creators: name: Novak, Katharina
name: Flöckner, Lukas
name: Erian, Anna
name: Freitag, Philipp
name: Herwig, Christoph
name: Pflügl, Stefan
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 60506 Virology

description: Additional file 2: Table S1. Mean fold change values including standard errors for the four comparisons A, B, C, D (named in the same way as in Figure 1 of the manuscript). Values highlighted in green represent significantly different expression levels (p-value 0.05). Table S2. qPCR program used for gene expression analysis. Lid temperature was set to 95 °C. Table S3. List of primers for gene expression analysis.
Intermittency and Multidimensional Correlations
Creators: name: Sarcevic, I.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We review recent experimental results on intermittency and multidimensional particle correlations in high-energy leptonic, hadronic and nuclear collisions. We discuss different theoretical models, including self-similar cascading and QCD parton showers, models with phase transitions and the three-dimensional statistical field theory for multiparticle density fluctuations.
description: 10 pp, 4 figs (available on request), University of Arizona preprint AZPH-TH/92-34, Invited talk presented at VII International Symposium on Very High Energy Cosmic Ray Interactions, June 22-27, 1992, Ann Arbor
title: Research Collaboration Best Practices
Creators: name: Misra, Joya
Publisher: name: University of Massachusetts Amherst
Year: 2020

description: Time is a critical resource necessary to creating new collaborations. Faculty members need opportunities to interact, informally as well as formally, to develop ideas, and work well together. Developing shared language is especially necessary for interdisciplinary collaborations. Equity can be challenging; collaborations may appear “predatory,” with unequal involvement in the research, or unfair recognition of time and effort in PI/co-PI roles or in authorship. Collabora-tions should fairly credit researchers for the work they do, regardless of rank, gender, race, etc. Inclusion is another key approach. This matters both in collaborators treating each other’s insights with respect, and identifying the contributions diverse collaborators can make. Intellectual and demographic diversity is likely to lead to greater creativity and insight. Good communication and trust characterize the most successful research teams. While funding opportunities sometimes require developing new collaborations speedily, teams that have already developed strategies for working together effectively are more likely to win funding.
Evolution of passive film behavior on mechanically polished NiTi shape memory alloy during forward martensitic transformation
Creators: name: Mohajeri, Mahdi
name: Castaneda, Homero
name: Lagoudas, Dimitris C
Publisher: name: arXiv
Year: 2018
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The corrosion property of Nickel-titanium (NiTi) shape memory alloy is investigated during forward martensitic transformation between 40C and 0C. The Differential Scanning Calorimetry technique is used to find the forward and reverse martensitic transformation temperatures. NiTi shows the present of martensitic phase at near room temperature by cooling from 80C. The change in corrosion behavior is monitored by electrochemical Open Circuit Potential (OCP) during phase transformation. Cyclic potentiodynamic polarization method is used to identify the corrosion compound of NiTi. Corrosion rate at each temperature extracted from polarization data and activation energy for corrosion reaction in martensite and austenite phase are calculated based on an Arrhenius relation between corrosion current density and reciprocal temperature.
description: Accepted and presented in "EUROCORR 2017 & 20th ICC & Process Safety Congress 2017"
Data of SYNCRIP/hnRNP Q in LIN28B/let-7 control
Creators: name: Chang, Jei-Sheng
name: LIN, TI
name: Jhang, Xin-Yue
name: Chan, Shih-Peng
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 329999
subject: Other biomedical and clinical sciences not elsewhere classified

description: The RNA-binding protein LIN28B represses the biogenesis of the tumor suppressor let-7. The LIN28B/let-7 axis regulates cell differentiation and is associated with various cancers. The RNA-binding protein Q (hnRNP Q) or SYNCRIP (Synaptotagmin Binding Cytoplasmic RNA Interacting Protein) has been implicated in mRNA splicing, mRNA transport, translation, and miRNAs biogenesis as well as metabolism in cancer. To determine whether hnRNP Q plays a role in the LIN28B/let-7 axis, we tested for interactions between hnRNP Q and LIN28B. We demonstrated that hnRNP Q interacts with LIN28B in an RNA-dependent manner. Knockdown of hnRNP Q caused reduced expression of a well-known let-7 target TRIM71, an E3 ubiquitin ligase that belongs to the RBCC/TRIM family, and also LIN28B, whose mRNA itself is down-regulated by let-7. In addition, hnRNP Q knockdown increased let-7 family miRNA levels and reduced the activity of luciferase reporters fused with the TRIM71 3'UTR or a synthetic 3'UTR carrying 8X let-7 complementary sites. Finally, depletion of hnRNP Q inhibited the proliferation of a hepatocellular carcinoma cell line, Huh7. This observation is consistent with the survival curve for liver cancer patients from the TCGA database, which indicates that high expression of hnRNP Q is a prognostic marker for a poor outcome in individuals afflicted with hepatocellular carcinoma. Together, our findings suggest that hnRNP Q interacts with LIN28B and modulates the LIN28B/let-7 axis in hepatocellular carcinoma.
«Il nostro più grande romanzo del ’900». Scrittori sulle tracce di Alessandro Manzoni
Creators: name: Palazzolo, Giuseppe
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Alessandro Manzoni
Romanzo
Mario Pomilio
Natalia Ginzburg
Novel

description: Andrea Camilleri definisce “I Promessi Sposi” come “Il nostro più grande romanzo del ’900”. Il presente saggio mira a collegare il romanzo di Natalia Ginzburg, “La famiglia Manzoni” e “Il Natale del 1833” di Mario Pompilio con i testi di Gadda, Bufalino, Sciascia, Primo Levi e altri ancora, allo scopo di identificare Manzoni come un personaggio del romanzo, unitamente alla sua intima e irrequieta meditazione su Dio e sulla presenza del male nella storia.
description: Andrea Camilleri defines ‘I Promessi Sposi’ «Il nostro più grande romanzo del ‘900». The present essay aims link Natalia Ginzburg’s novel, ‘La famiglia Manzoni’, and Mario Pomilio’s ‘Il Natale del 1833’. To texts of Gadda, Bufalino, Sciascia, Primo Levi, and others, in the attempt to identify Manzoni as novel character, his intimate and restless meditation on God and on the presence of evil in history.
Ai margini del testo poetico: Leopardi e la scrittura
Creators: name: Castori, Loredana
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Bellezza
Scultura
Poesia
Immaginazione
Beauty
Sculpture
Poetry
Imagination

description: Il saggio ripercorre alcune opere di Leopardi considerando, a margine del testo poetico, il rapporto con la scultura neoclassica. La passione per la grazia e la bellezza che ha ispirato le opere di Canova, ma anche di Pietro Tenerani, da Leopardi conosciuto per il tramite di Carlotta Lenzoni, diventato ispiratore delle sue “Sepolcrali”.
description: The essay by Loredana Castori traces some of Leopardi’s works considering, in the margin of the poetic text, the relationship with neoclassical sculpture. The passion for grace and beauty that inspired the works of Canova, but also of Pietro Tenerani, from Leopardi known through Carlotta Lenzoni, who became the inspiration for his ‘Sepolcrali’.
Constraining Stellar Coronal Mass Ejections Through Multi-Wavelength Analysis of the Active M Dwarf EQ Peg
Creators: name: Crosley, M. K.
name: Osten, R. A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Stellar coronal mass ejections remain experimentally unconstrained, unlike their stellar flare counterparts which are observed ubiquitously across the electromagnetic spectrum. Low frequency radio bursts in the form of a type II burst offer the best means of identifying and constraining the rate and properties of stellar CMEs. CME properties can be further improved through the use of proposed solar-stellar scaling relations and multi-wavelength observations of CMEs through the use of type II bursts and the associated flare expected to occur occur alongside. We report on 20 hours of observation of the nearby, magnetically active, and well characterized M dwarf star EQ Peg. The observations are simultaneously observed with the Jansky Very Large Array at their P-band (230-470 MHz) and at the Apache Point observatory in the SDSS u' filter ($λ$ = 3557 Å). Dynamic spectra of the P band data, constructed to search for signals in the frequency-time domains, did not reveal evidence for drifting radio bursts that could be ascribed to type II bursts. Given the sensitivity of our observations, we are able to place limits on the brightness temperature and source size of any bursts which may have occurred. Using solar scaling rations on four observed stellar flares, we predict CME parameters. Given the constraints on coronal density and photospheric field strength, our models suggest that the observed flares would have been insufficient to produce detectable type II bursts at our observed frequencies. We consider the implications of these results, and other recent findings, on stellar mass loss.
description: 35 pages, 7 figures
La vita e la scena. Le «Strette di mano» di Peppino de Filippo
Creators: name: Cannavacciuolo, Laura
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Peppino De Filippo
Strette di mano
Teatro
Novecento
Napoli
Theater
Twentieth century
Imagination

description: L’articolo prende in esame il volume di prose di Peppino De Filippo, “Strette di mano” (Marotta, 1974), in cui il drammaturgo napoletano raccoglie alcuni scritti pubblicati tra il 1969 e il 1971 sulle pagine del «Messaggero». In esse presenta un affresco della scena teatrale italiana dell’epoca attraverso il racconto di alcuni degli incontri memorabili che hanno segnato la sua carriera artistica. All’interno del volume si susseguono i ritratti delle più eminenti personalità della vita teatrale e cinematografica italiana (Ettore Petrolini, Ermete Zacconi, Angelo Musco, Il Principe de Curtis, federico Fellini, Luigi Pirandello); non si tralasciano, tuttavia, alcuni professionisti della penna (Indro Montanelli, Angelo Rizzoli, Ugo Ricci, Adolfo Cotronei), e illustri cariche di Stato con le quali il giovane De Filippo ebbe modo di conoscere (Vittorio Emanuele III, il Duca di Gloucester). I personaggi celebrati in queste prose, oltre ad essere pubblicamente omaggiati per le loro capacità artistiche, forniscono l’“occasione” per riflettere sulla difficile situazione del teatro in Italia, sulle insidie ad esso arrecate dal successo del cinematografo e, soprattutto, sulla faciloneria con cui una certa classe intellettuale tende a liquidare la «comicità» e il lavoro degli attori «comici».
description: This article examines Peppino De Filippo’s velume of prose, ‘Strette di Mano’ (Marotta, 1974) where the playwright collects some of his works published from 1969 to 1971 in “Il Messaggero”. Such a collection depicts the Italian theatrical scene at the time through the stories of some of the memorable encounters which marked his artistic career. In the volume, he portraits some of the most eminent protagonists of the Italian theatrical and cinematographic life (Ettore Petrolini, Ermete Zacconi, Angelo Musco, Il Principe de Curtis, Federico Fellini, Luigi Pirandello); moreover, sone famous writers are mentioned (Indro Montanelli, Angelo Rizzoli, Ugo Ricci, Adolfo Coreonei) as well as some distinguished representatives of the State that the young De Filippo could meet (Vittorio Emanuele III, the Duke of Gloucester). On the one hand, the characters celebrated in these prose compositions are recognized for their artistic abilities; on the other hand, they are good occasions to refer to the difficult condition of theatre in Italy, to its pitfalls as caused by cinematographic success and, above all, to the laziness of some intellectuals who use to diminish the role of humor and the comic actors’ work.
Competition between Pressure and Gravity Confinement in Lyman-Alpha Forest Observations
Creators: name: Charlton, Jane C.
name: Salpeter, Edwin E.
name: Linder, Suzanne M.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A break in the distribution function of Ly$α$ clouds (at a typical redshift of $2.5$) has been reported by Petitjean et al. (1993). This feature is what would be expected from a transition between pressure confinement and gravity confinement (as predicted in Charlton, Salpeter, and Hogan (1993)). The column density at which the feature occurs has been used to determine the external confining pressure, $\sim 10 {\rm cm}^{-3} {\rm K}$, which could be due to a hot, intergalactic medium. For models that provide a good fit to the data, the contribution of the gas in clouds to $Ω$ is small. The specific shape of the distribution function at the transition (predicted by models to have a non-monotonic slope) can serve as a diagnostic of the distribution of dark matter around Ly$α$ forest clouds, and the present data already eliminate certain models.
description: 10 pages plain TeX, 2 figures available upon request, submitted to ApJ Letters, PSU-jc-1
Accurate Sine-Wave Amplitude Measurements Using Nonlinearly Quantized Data
Creators: name: Carbone, Paolo
name: Schoukens, Johan
name: Kollár, István
name: Moschitta, Antonio
Publisher: name: arXiv
Year: 2018
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The estimation of the amplitude of a sine wave from the sequence of its quantized samples is a typical problem in instrumentation and measurement. A standard approach for its solution makes use of a least squares estimator (LSE) that, however, does not perform optimally in the presence of quantization errors. In fact, if the quantization error cannot be modeled as an additive noise source, as it often happens in practice, the LSE returns biased estimates. In this paper, we consider the estimation of the amplitude of a noisy sine wave after quantization. The proposed technique is based on a uniform distribution of signal phases and it does not require that the quantizer has equally spaced transition levels. The experimental results show that this technique removes the estimation bias associated with the usage of the LSE and that it is sufficiently robust with respect to small uncertainties in the known values of transition levels.
Gesualdo Bufalino e il sortilegio di Paul-Jean Toulet
Creators: name: Cacciatore, Giulia
Publisher: name: Avellino : Associazione culturale Internazionale Sinestesie
Year: 2019
Subjects: Gesualdo Bufalino
Paul-Jean Toulet
Filologia
Traduzione
Philology
Translation

description: Gesualdo Bufalino, ancora scrittore segreto, si cimentò con la traduzione delle “Contrerimes” di J.-P. Toulet per circa un ventennio. Si trattò di un confronto anzitutto esistenziale, prima che letterario, un lungo percorso di riflessione su quelli che diventeranno, dopo l’esordio, i temi principali della sua scrittura, la malattia e la memoria. Attraverso nuovi documenti d’archivio è possibile sia ipotizzare una datazione della traduzione, sia individuare i nessi letterari tra la poetica bufaliniana e quella di Toulet, a più voci considerato come uno dei maggiori poeti francesi di fine Ottocento.
description: Gesualdo Bufalino, still a secret writer, grappled with the translation of the ‘Contrerimes’ by J.-P. Toulet for about twenty years. It was primarily an existential comparison, before being a literary confrontation, a long journey of reflection on those that will become, after the debut, the main themes of his works: desease and memory. Through the analysis of new archival documents it is possible to speculate a dating of the translation, and to edentify the literary links between Bufalino’s poetics and that of Toulet, considered one of the greatest French poets of late nineteenth century.
Pathways and Protective Factors: Modelling the Effect of Chronic Conditions on Quality of Life in Midlife and Older Irish Adults
Creators: name: Sexton, Eithne
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Background: Quality of life (QoL) outcomes are increasingly important as a target for healthcare intervention and for measuring healthcare effectiveness. However, the effect of physical health on QoL at older ages is poorly understood. The aim of this thesis was to empirically test an explanatory model of the relationship between chronic conditions and QoL in older people in Ireland. Methods: This is a cross-sectional and longitudinal cohort study, using data from the Irish Longitudinal Study of Ageing (TILDA), a general-population sample of community-dwelling adults aged 50+ in the Republic of Ireland (n=8,175). Exploratory and confirmatory factor analysis was used to evaluate and revise the CASP-19 measure of QoL. Structural equation modelling was used to test a model of the pathway between chronic conditions and QoL, via disability and affective wellbeing. Conditional change linear regression was used to evaluate longitudinal effects along this pathway, and to examine how these longitudinal effects were modified by personal characteristics (e.g., personality) and environmental factors (e.g., social support). Results: A 12-item version of CASP-19 was developed, comprising two dimensions: control/autonomy and self-realisation/pleasure. The cross-sectional effect of chronic conditions on both QoL dimensions was mediated by physical impairment and affective wellbeing. Partner support reduced the effect of physical impairment on control/autonomy and religiosity reduced the effect of physical impairment on self-realisation/pleasure. Self-realisation/pleasure was less responsive to variation and change in physical health relative to control/autonomy. Conclusion: The effect of chronic conditions on QoL in later life depends on the level of disability, the availability of environmental supports, and personal characteristics. Models of healthcare which focus on patient-specific goals, circumstances and health needs, rather than specific conditions and disease processes, may be more effective for improving QoL outcomes in chronic disease. Control/autonomy emerged as a useful indicator of QoL which is responsive to variation in physical health.