cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Varianten- und Komplexitätsmanagement in industriellen Produktionsprozessen
Creators: name: Sander, Hendrik
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2008
Subjects: subject: Automobilindustrie
subject: Management
subject: Kostenanalyse
subject: Produktionssystem
subject: Simulation
classificationCode: 600
subject: 600 Technik, Technologie

description: Die vorliegende Diplomarbeit basiert auf dem Praxisbericht, der während der Mitarbeit im Forschungsprojekt ILIPT (Intelligent Logistics for Innovative Product Technologies) an der Leuphana Universität Lüneburg entstand. Eine steigende Anzahl von Kunden hegt bei einem Neuwagenkauf den Wunsch nach einem speziell auf ihre Wünsche zugeschnittenen Fahrzeug. Diesem Trend zur Individualisierung begegnen die Automobilkonzerne mit einem umfangreichen Angebot an Fahrzeugvarianten. Da jedoch gleichzeitig ein anhaltend hoher Druck des Marktes zur Kostenvermeidung besteht, rückt das Management von Varianten und der daraus resultierenden Komplexität, immer stärker in den Fokus des Interesses. Ist die Komplexität zu hoch, steigen die Ausgaben rapide. Eine maximale Reduktion der variantengetriebenen Komplexität ist jedoch in den wenigsten Fällen die Lösung des Problems: Gibt es zu wenig Varianten sinkt die Attraktivität für den Kunden, da eine ausreichende Befriedigung seiner Bedürfnisse nicht mehr gegeben ist. Deshalb gilt es, ein Komplexitätsoptimum zu erreichen. Bei diesem Ziel fällt einer Prognose über die Entwicklung der Komplexitätskosten bei einer Veränderung der Variantenzahl eine besondere Bedeutung zu. In dieser Diplomarbeit geht es um die Möglichkeit, derartige Kosten mit Hilfe von Simulationen abzuschätzen und um eine Analyse des derzeitigen Standes der Technik auf diesem Gebiet. Beginnend mit einer Literaturrecherche werden im Anschluss vorhandene Werkzeuge betrachtet und schließlich die bisherigen Ansätze zur Erstellung eines Komplexitätskostenmodells analysiert.
Day of Archaeology in Macedonia 3
Creators: name: Archaeologica
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Euchromius Guenée 1845
Creators: name: Landry, Bernard
name: Léger, Théo
name: Nuss, Matthias
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Crambidae
Euchromius

description: (b) Euchromius Guenée, 1845 (gender: masculine),
type species by subsequent designation by Desmarest, 1857: Tinea bella Hübner, 1796;
description: Published as part of Landry, Bernard, Léger, Théo & Nuss, Matthias, 2020, Case 3819 - Euchromiini Léger, Landry & amp; Nuss, 2019 (Insecta, Lepidoptera, Crambidae) and Euchromiinae Butler, 1876 (Insecta, Lepidoptera, Erebidae): proposed resolution of homonymy by emending the former to Euchromiusini, pp. 83 in Bulletin of Zoological Nomenclature 77 (1) on page 84, DOI: 10.21805/bzn.v77.a027, http://zenodo.org/record/15085591
It Isn t All Fieldwork!
Creators: name: Johnston, Susan
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
U.S. Military Veterans Contribute to Archaeology
Creators: name: Aeadams83
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
The Business of Archaeology
Creators: name: Touton, Michelle
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Outage Efficient Strategies for Network MIMO with Partial CSIT
Creators: name: Kobayashi, Mari
name: Yang, Sheng
name: Debbah, Merouane
name: Belfiore, Jean-Claude
Publisher: name: arXiv
Year: 2010
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We consider a multi-cell MIMO downlink (network MIMO) where $B$ base-stations (BS) with $M$ antennas connected to a central station (CS) serve $K$ single-antenna user terminals (UT). Although many works have shown the potential benefits of network MIMO, the conclusion critically depends on the underlying assumptions such as channel state information at transmitters (CSIT) and backhaul links. In this paper, by focusing on the impact of partial CSIT, we propose an outage-efficient strategy. Namely, with side information of all UT's messages and local CSIT, each BS applies zero-forcing (ZF) beamforming in a distributed manner. For a small number of UTs ($K\leq M$), the ZF beamforming creates $K$ parallel MISO channels. Based on the statistical knowledge of these parallel channels, the CS performs a robust power allocation that simultaneously minimizes the outage probability of all UTs and achieves a diversity gain of $B(M-K+1)$ per UT. With a large number of UTs ($K \geq M$), we propose a so-called distributed diversity scheduling (DDS) scheme to select a subset of $\Ks$ UTs with limited backhaul communication. It is proved that DDS achieves a diversity gain of $B\frac{K}{\Ks}(M-\Ks+1)$, which scales optimally with the number of cooperative BSs $B$ as well as UTs. Numerical results confirm that even under realistic assumptions such as partial CSIT and limited backhaul communications, network MIMO can offer high data rates with a sufficient reliability to individual UTs.
description: 26 pages, 8 figures, submitted to IEEE Trans. on Signal Processing
Additional file 1 of Stable maternal proteins underlie distinct transcriptome, translatome, and proteome reprogramming during mouse oocyte-to-embryo transition
Creators: name: Zhang, Hongmei
name: Ji, Shuyan
name: Zhang, Ke
name: Chen, Yuling
name: Ming, Jia
name: Kong, Feng
name: Wang, Lijuan
name: Wang, Shun
name: Zou, Zhuoning
name: Xiong, Zhuqing
name: Xu, Kai
name: Lin, Zili
name: Huang, Bo
name: Liu, Ling
name: Fan, Qiang
name: Jin, Suoqin
name: Deng, Haiteng
name: Xie, Wei
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Supplementary figure and figure legends. Figure S1. Validation of LC-MS/MS quantification ability in mouse oocytes. Figure S2. Evaluation of LC-MS/MS data quality in mouse oocytes and early embryos. Figure S3. Dynamic changes of RPF and mRNA in the mouse oocytes and early embryos. Figure S4. Correlation between protein and mRNA across developmental stages. Figure S5. Differentially expressed proteins and genes at each consecutive stage. Figure S6. Correlation between protein and RPF or mRNA for individual genes across developmental stages. Figure S7. Protein features related to the concordance between protein and RPF or mRNA.
Deligne-Beilinson cohomology and abelian link invariants: torsion case
Creators: name: Thuillier, Frank
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: For the abelian Chern-Simons field theory, we consider the quantum functional integration over the Deligne-Beilinson cohomology classes and present an explicit path-integral non-perturbative computation of the Chern-Simons link invariants in $SO(3)\simeq\mathbb{R}P^3$, a toy example of 3-manifold with torsion.
Back to School
Creators: name: May, Sarah
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
The Monetary Value of Cultural Goods: A Contingent Valuation Study of the Municipal Supply of Cultural Goods in Lueneburg
Creators: name: Last, Anne-Kathrin
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2007
Subjects: subject: Cultural Good
subject: Contingent Valuation
subject: Willingness to Pay
subject: Kulturgut
subject: Zahlungsbereitschaft
subject: Kontingenter Bewertungsansatz
classificationCode: 330
subject: 330 Wirtschaft

description: This paper aims to determine if the contingent valuation method (CVM) can provide valid results useful in policy-making. This will be investigated by using a CV study that captures the willingness to pay (WTP) for the municipal cultural supply in Lueneburg, Germany. In contrast to previous CV studies that included a wide range of descriptive statistics, the empirical analysis of the current study focuses on multivariate analysis to explore the factors associated with the WTP. The results reflect current hypotheses in cultural economics. Thus, higher education levels and higher income are positively correlated with higher WTP. While the results indicate a highly significant impact of non-use values on the WTP for cultural goods across the different regression models, the findings for some variables differ considerably in magnitude across different regression models.
In silico generation of peptides by replica exchange monte carlo: Docking-based optimization of maltose-binding-protein ligands
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Algorithms
Amino Acid Sequence
Fluorescence
Immobilized Proteins
Kinetics
Ligands
Maltose-Binding Proteins
Molecular Docking Simulation
Molecular Sequence Data
Monte Carlo Method
Peptides
Protein Binding
Spectrometry, Mass, Electrospray Ionization
Surface Plasmon Resonance
Thermodynamics
Tryptophan

description: © 2015 Russo et al. Short peptides can be designed in silico and synthesized through automated techniques, making them advantageous and versatile protein binders. A number of docking-based algorithms allow for a computational screening of peptides as binders. Here we developed ex-novo peptides targeting the maltose site of the Maltose Binding Protein, the prototypical system for the study of protein ligand recognition.We used a Monte Carlo based protocol, to computationally evolve a set of octapeptides starting from a polialanine sequence. We screened in silico the candidate peptides and characterized their binding abilities by surface plasmon resonance, fluorescence and electrospray ionization mass spectrometry assays. These experiments showed the designed binders to recognize their target with micromolar affinity. We finally discuss the obtained results in the light of further improvement in the exnovo optimization of peptide based binders. Copyright:
Legume-Grass Pastures Enhanced the Growth of Yearling Kiko Does
Creators: name: Tiwari, Anand
name: Karki, Uma
name: Paneru, Bidur
name: Ellis, Nevershi
name: Karki, Lila B.
name: Tiwari, Anand
name: Karki, Uma
name: Paneru, Bidur
name: Ellis, Nevershi
name: Karki, Lila B.
Publisher: name: Unknown
Year: 2021
Subjects: subject: Livestock Production/Industries
subject: Productivity Analysis
subject: Legume
subject: Grass
subject: Pastures
subject: Animal Growth
subject: Yearling Kiko Does

description: Legumes can be beneficial in increasing pasture productivity and goat performance. This study’s objective was to evaluate the impact of legume-grass pastures on goat performance. A 50:50 mixture of hairy vetch (Vicia villosa Roth) and Marshall ryegrass (Lolium L.) or hairy vetch and rye (Secale L.) was sown on 50% of the research area and 50% with Marshall ryegrass or rye. Forage samples were collected and processed for dry matter. Yearling Kiko does (19) were divided into two groups: legume-grass mix (10 does) and grass only (9 does), both rotationally stocked in their respective plots. Animal live weight, FAMACHA score, and body condition score were collected at the beginning, fortnightly, and at the end of the study. The goat group on legume-grass pasture gained more weight (67 ± 0.9 lb.) than the group on the grass pasture (65 ± 0.9 lb.) (p<0.05). Results indicated that legume-grass pastures promote the performance of growing does compared to sole-grass pastures.
Euchromiinae Butler 1876
Creators: name: Landry, Bernard
name: Léger, Théo
name: Nuss, Matthias
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae

description: (a) EUCHROMIINAE Butler, 1876,
type genus: Euchromia Hübner, 1819; and
description: Published as part of Landry, Bernard, Léger, Théo & Nuss, Matthias, 2020, Case 3819 - Euchromiini Léger, Landry & amp; Nuss, 2019 (Insecta, Lepidoptera, Crambidae) and Euchromiinae Butler, 1876 (Insecta, Lepidoptera, Erebidae): proposed resolution of homonymy by emending the former to Euchromiusini, pp. 83 in Bulletin of Zoological Nomenclature 77 (1) on page 84, DOI: 10.21805/bzn.v77.a027, http://zenodo.org/record/15085591
title: Управление персоналом в социально-культурной деятельности
Creators: name: ELS IPR BOOKS
Publisher: name: Вузовское образование
Year: 2021

description: В учебном пособии рассматриваются вопросы стратегического управления персоналом, обучением, мотивацией; оценка результативности персонала, безопасность, условия и дисциплина труда, касающиеся различных аспектов управления персоналом в сфере социально-культурной деятельности (СКД). Разделы сопровождаются вопросами и заданиями для самоконтроля и работы в аудитории. Подготовлено в соответствии с Федеральным государственным образовательным стандартом высшего образования. Учебное пособие предназначено для изучения дисциплины «Управление персоналом в социально-культурной деятельности» студентами, обучающимися по направлению подготовки 51.03.03 «Социально-культурная деятельность» (профиль «Менеджмент социально-культурной деятельности»). Издание может быть также рекомендовано магистрантам, занимающимся проблемами управления и бизнеса в сфере культуры и социально-культурной деятельности.
Mannerist elements in the songs and sonnets of John Donne
Creators: name: Holmes, Richard Arthur
Publisher: name: University of British Columbia
Year: 2011

description: For a long time Mannerism has been a critical term peculiar to the Fine Arts. In the last twenty years it has attracted the attention of literary critics who have sought to clarify its relation to literature in both theory and practice. This thesis draws on the conclusions of such writers and applies them to the Songs and Sonnets of John Donne in an attempt to understand him within the Mannerist context—that is, as a poet expressing characteristics of style, sensibility and culture that are originally typified by a group of sixteenth-century Italian artists. The mode of criticism proceeds on the basis that it is possible to abstract distinctive features from a given style in one art form and apply them, by analogy, to another: thus, discontinuous lines in painting may be seen as analogous to broken sentences in language, or the effect of distorted perspective may be likened to the effect of structural irregularity in a poem. The process may be further supported by reference to cultural, personal or theoretical circumstances that are common to the artist/poets concerned. In this thesis, the views of certain scholars as to the nature of Mannerism have been applied to Donne. Thus his wit, his dramatic techniques, his use of convention and his ambiguity have all been examined in the light of Mannerist principles, and have been further exemplified by reference to the fine and plastic arts. The conclusions reached are that, first, it is possible to approach Donne from a Mannerist viewpoint, that in so doing insights into the nature and organisation of the poetry follow, and that by setting Donne in a European artistic context, something of the insularity and arbitrariness of 'metaphysical' may yield to the broader frame of reference that Mannerism provides.
title: Vorbereitung zur Wiederverwendung: Regelung und Regelungsbedarf - Umsetzungs- und Erfolgsaussichten
title: Preparing for re-use: Regulation and need for regulation - Prospects for implementation and success
titleType: AlternativeTitle
Creators: name: Guerra González, Jorge
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2020
Subjects: subject: Abfall
subject: Kreislaufwirtschaft
subject: Suffizienz
subject: Konsumentenverhalten
subject: Ressourcenschutz
classificationCode: 333.7
subject: 333.7

description: Re-use of recovered materials is to be understood as a strategy concerning resource protection. Thanks to recovery measures that have this goal - preparation for re-use - materials that were once defined as waste can carry out their original function, so that in principle, less resources must be utilized for the development of new products. At least theoretically, it would be possible to combine sustainable development and eco-nomic growth. Owing to this potential, re-use and preparation for re-use are granted a high position in the waste hierarchy. Nevertheless, reality shows that the possibilities for its implementation are rather humble. This paper analyses the reasons for and consequences of this phenomenon
description: Wiederverwendung (WV) von Erzeugnissen ist als Ansatz hinsichtlich der Ressourcenschonung zu verstehen. Durch Verwertungsmaßnahmen mit dieser Zielsetzung - Vorbereitung zur Wiederverwendung (VWV) - kann man bewirken, dass einst als Abfall eingestufte Erzeugnisse ihre ursprüngliche Funktion wieder erfüllen, so dass im Prinzip weniger Ressourcen für die Bereitstellung von neuen Produkten beansprucht werden müs-sen. Zumindest theoretisch wäre es dann möglich, nachhaltige Entwicklung mit Wirtschaftswachstum zu vereinbaren. Aus diesem Potenzial ergibt sich die hohe Stellung sowohl von WV als auch von VWV in der so-genannten Abfallhierarchie. Nichtsdestotrotz zeigt die Realität, dass die Umsetzungsmöglichkeiten von WV bzw. VWV bescheiden sind. Auf die Ursachen und Folgen dieses Phänomens geht dieser Aufsatz ein. Schlüsselwörter: Wiederverwendung, Abfallhierarchie, Effizienz, Suffizienz, Konsum-entenverhalten, Ressourcenschutz, Nachhaltigkeit, Kreislaufwirtschaft
No difference in perceived intensity of linoleic acid in the oral cavity between obese and nonobese individuals
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: bioelectrical impedance
children
fat taste
linoleic acid
psychophysical testing
taste intensity

description: © The Author 2015. Published by Oxford University Press. Findings from studies examining interactions between fat taste and dietary fat intake or body weight are mixed. A convenience sample of 735 visitors to the Denver Museum of Nature & Science ≥8 years old rated the taste intensity of edible taste strips impregnated with varying concentrations (%v/v) of linoleic acid (LA) (blank = 0.0, low = 0.06, medium = 0.15, high = 0.38). Percent body fat (BF%) was measured using bioelectrical impedance. Fat taste intensity was rated as significantly different across all concentrations (P < 0.001) except between the blank and low concentrations (P = 0.1). Ratings increased monotonically across concentrations. Children (<18 years; N = 180) rated all concentrations as more intense than adults (P < 0.001 for all). Women and girls rated the highest concentration as more intense than men and boys (P < 0.02 for all). BF% was not correlated with fat taste intensity ratings. Self-reported dietary intake indicated that obese individuals' intensity ratings for medium and high concentrations of LA were inversely related to recent mono- and poly-unsaturated fat exposure (r = -0.19 to -0.27; P < 0.03 for all). No such associations were observed in the nonobese group. Findings suggest that factors other than simple adiposity status influence fat taste intensity ratings, and that participants in fat taste studies should receive standardized meals prior to testing.
title: Die naturschutzrechtliche Ausgestaltung besonderer Schutzgebiete in Umsetzung der Vogelschutzrichtlinie
title: Implementing special protection areas according to the Birds Directive under national nature protection law
titleType: AlternativeTitle
Creators: name: Niederhausen, Inga
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2020
Subjects: classificationCode: 598
subject: 598 Aves (Vögel)

description: The Birds Directive obliges the EU-member states to designate bird sanctuaries as Special Protection Areas (SPA)under national law. The legal suitability of nature reserves, protected landscape areas and contractual nature conservation replacing regulatory law was analyzed using the case study of the SPA Unterelbe. Often areas designated as “protected” are associated with conflicts between nature conservation and agricultural interests. In addition to a detailed examination of European, national and regional law, therefore also agri-environmental measures were considered in the analysis. For the area studied, the results show that norm replacing contracts are incompatible with EU law whilst nature reserves are legally entirely suitable. If protected landscape areas are in accordance with law to designate bird sanctuaries as SPA always needs to be assessed on a case-by-case basis.
description: Die Vogelschutzrichtlinie verpflichtet die EU-Mitgliedstaaten dazu, Vogelschutzgebiete (VSG) nach nationalem Recht zu besonderen Schutzgebieten zu erklären. Am Beispiel des VSG Unterelbe wurde die Eignung der ordnungsrechtlichen Instrumente des Natur- und andschaftsschutzgebietes (NSG, LSG) sowie normersetzender Verträge zur Sicherung von VSG untersucht. Oft gehen Schutzgebietsausweisungen mit Konflikten zwischen Naturschutz und Landwirtschaft einher. Neben einer detaillierten Betrachtung der europa-, bundes- und landesrechtlichen Vorgaben zur Sicherung von VSG, fanden daher Agrarumweltmaßnahmen Beachtung. Im Ergebnis zeigt sich, dass normersetzende Verträge europarechtswidrig sind, während das Instrument des NSG rechtlich uneingeschränkt geeignet ist. Ob ein LSG zur Sicherung eines VSG rechtskonform ist, muss stets in einer Einzelfallprüfung geklärt werden.
What fraction of duplicates observed in recently sequenced genomes is segregating and destined to fail to fix?
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: gene duplication
fixation
copy number variation
nonfunctionalization

description: © The Author(s) 2015. Most sequenced eukaryotic genomes show a large excess of recent duplicates. As duplicates age, both the population genetic process of failed fixation and the mutation-driven process of nonfunctionalization act to reduce the observed number of duplicates. Understanding the processes generating the age distributions of recent duplicates is important to also understand the role of duplicate genes in the functional divergence of genomes. To date, mechanistic models for duplicate gene retention only account for the mutation-driven nonfunctionalization process. Here, a neutral model for the distribution of synonymous substitutions in duplicated genes which are segregating and expected to never fix in a population is introduced. This model enables differentiation of neutral loss due to failed fixation from loss due to mutation-driven nonfunctionalization. The model has been validated on simulated data and subsequent analysis with the model on genomic data from human and mouse shows that conclusions about the underlying mechanisms for duplicate gene retention can be sensitive to consideration of population genetic processes.
Inflammation mediated metastasis: Immune induced epithelial-to-mesenchymal transition in inflammatory breast cancer cells
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Cell Line, Tumor
Cytokines
Epithelial-Mesenchymal Transition
Female
Humans
Inflammatory Breast Neoplasms
Neoplasm Metastasis
Neoplastic Cells, Circulating
Pilot Projects
T-Lymphocytes
Tumor Microenvironment

description: © 2015 Cohen et al. Inflammatory breast cancer (IBC) is the most insidious form of locally advanced breast cancer; about a third of patients have distant metastasis at initial staging. Emerging evidence suggests that host factors in the tumor microenvironment may interact with underlying IBC cells to make them aggressive. It is unknown whether immune cells associated to the IBC microenvironment play a role in this scenario to transiently promote epithelial to mesenchymal transition (EMT) in these cells. We hypothesized that soluble factors secreted by activated immune cells can induce an EMT in IBC and thus promote metastasis. In a pilot study of 16 breast cancer patients, TNF-α production by peripheral blood T cells was correlated with the detection of circulating tumor cells expressing EMT markers. In a variety of IBC model cell lines, soluble factors from activated T cells induced expression of EMT-related genes, including FN1, VIM, TGM2, ZEB1. Interestingly, although IBC cells exhibited increased invasion and migration following exposure to immune factors, the expression of E-cadherin (CDH1), a cell adhesionmolecule, increased uniquely in IBC cell lines but not in non-IBC cell lines. A combination of TNF-α, IL-6, and TGF-β was able to recapitulate EMT induction in IBC, and conditioned media preloaded with neutralizing antibodies against these factors exhibited decreased EMT. These data suggest that release of cytokines by activated immune cells may contribute to the aggressiveness of IBC and highlight these factors as potential target mediators of immune-IBC interaction.
Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Amino Acid Sequence
Animals
Bees
Binding Sites
Insecticides
Ion Channel Gating
Molecular Docking Simulation
Molecular Sequence Data
Protein Binding
Protein Conformation
Sodium Channel Blockers
Toxicity Tests
Voltage-Gated Sodium Channels

description: Pollination is important for both agriculture and biodiversity. For a significant number of plants, this process is highly, and sometimes exclusively, dependent on the pollination activity of honeybees. The large numbers of honeybee colony losses reported in recent years have been attributed to colony collapse disorder. Various hypotheses, including pesticide overuse, have been suggested to explain the disorder. Using the Xenopus oocytes expression system and two microelectrode voltage-clamp, we report the functional expression and the molecular, biophysical, and pharmacological characterization of the western honeybee's sodium channel (Apis Mellifera NaV1). The NaV1 channel is the primary target for pyrethroid insecticides in insect pests. We further report that the honeybee's channel is also sensitive to permethrin and fenvalerate, respectively type I and type II pyrethroid insecticides. Molecular docking of these insecticides revealed a binding site that is similar to sites previously identified in other insects. We describe in vitro and in silico tools that can be used to test chemical compounds. Our findings could be used to assess the risks that current and next generation pesticides pose to honeybee populations.
Reasons low-income parents offer snacks to children: How feeding rationale influences snack frequency and adherence to dietary recommendations
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: snacks
parenting
childhood obesity prevention
child feeding

description: © 2015 by the authors; licensee MDPI, Basel, Switzerland. Although American children snack more than ever before, the parental role in promoting snacking is not well understood. In 2012–2013 at baseline in an intervention study to prevent childhood obesity in low-income Massachusetts communities, n = 271 parents of children aged 2–12 years completed surveys regarding nutritive and non-nutritive reasons they offered children snacks, demographics, and dietary factors. An analysis of variance demonstrated that parents reported offering snacks (mean/week; standard deviation (SD)) for nutritive reasons like promoting growth (¯x = 2.5; SD 2.2) or satisfying hunger (¯x = 2.4; SD 2.1) almost twice as often as non-nutritive reasons like keeping a child quiet (¯x = 0.7; SD 1.5) or celebrating events/holidays (¯x = 0.8; SD 1.1). Parents reported giving young children (2–5 years) more snacks to reward behavior (1.9 vs. 1.1, p < 0.001), keep quiet (1.0 vs. 0.5, p < 0.001), and celebrate achievements (1.7 vs. 1.0, p < 0.001) than parents of older children (6–12 years). Multivariable logistic regression models were used to obtain adjusted odds ratios, which indicated reduced child adherence to dietary recommendations when parents offered snacks to reward behavior (Odds Ratio (OR) = 0.83; 95% Confidence Interval (CI) 0.70–0.99), celebrate events/holidays (OR = 0.72; 95% CI 0.52–0.99), or achievements (OR = 0.82; 95% CI 0.68–0.98). Parental intentions around child snacking are likely important targets for obesity prevention efforts.
Ground reaction forces in uphill and downhill trail running: a pilot outdoor study
Creators: name: Wohlgut, Valentin
name: Siebler, Lea
name: Compeyron, Robin
name: Senner, Veit
Publisher: name: Loughborough University
Year: 2024

description: Engineering of Sport 15 - Proceedings from the 15th International Conference on the Engineering of Sport (ISEA 2024)
Trail running is a unique and challenging form of running in natural terrain that requires specific biomechanical and physiological adaptations of the athlete. Changing inclination and surfaces (e.g., mud, gravel, rocks) alter kinetic and kinematic parameters. Laboratory studies on treadmills have already investigated the relationship between slope and running speed. However, especially in trail running, we should consider the influence of natural surfaces. Zrenner et al. (2020) showed the impact of different ground surface conditions on running kinematics with inertial measurement units mounted on the shoes, which cannot be reproduced in this form in the laboratory. For the first time, we present a pilot study focusing on ground reaction forces during uphill and downhill running on soft forest soil measured outdoors with a covered force plate. Understanding the shoe-ground interaction in real-world environments is crucial to optimize future trail running shoes.
It depends whose data are being shared: Considerations for genomic data sharing policies
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: data sharing
genomic
policy
privacy
research
trust

description: © The Author 2015. There is an urgent need for consistent data sharing policies that promote the advancement of science while respecting the values and interests of those providing their genetic data for research. Responding to the article of Jalayne J. Arias, Genevieve Pham-Kanter, and Eric G. Campbell, 'The Growth and Gaps of Genetic Data Sharing Policies in the United States', this commentary further explores the challenges of human subjects' protection in existing data sharing policies. We will elaborate on the need for data sharing policies to accommodate variation in individual and group preferences around data sharing and privacy concerns by comparing our previously published data on patients' and parents' consent to data sharing and attitudes about privacy to data from focus groups with HIV-positive, underserved individuals who were asked about their willingness to participate in genetic research and share their data broadly. These studies support the observation of Arias, Pham-Kanter, and Campbell that researchers, and funding agencies will need to balance the privacy interests of groups as well as individuals in future genomic data sharing policies.
Mutagenesis screen identifies agtpbp1 and eps15L1 as essential for T lymphocyte development in zebrafish
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Animals
Carboxypeptidases
Cell Differentiation
Gene Expression
Gene Knockdown Techniques
Hematopoiesis
Mutagenesis
T-Lymphocytes
Zebrafish
Zebrafish Proteins

description: Genetic screens are a powerful tool to discover genes that are important in immune cell development and function. The evolutionarily conserved development of lymphoid cells paired with the genetic tractability of zebrafish make this a powerful model system for this purpose. We used a Tol2-based gene-breaking transposon to induce mutations in the zebrafish (Danio rerio, AB strain) genome, which served the dual purpose of fluorescently tagging cells and tissues that express the disrupted gene and provided a means of identifying the disrupted gene. We identified 12 lines in which hematopoietic tissues expressed green fluorescent protein (GFP) during embryonic development, as detected by microscopy. Subsequent analysis of young adult fish, using a novel approach in which single cell suspensions of whole fish were analyzed by flow cytometry, revealed that 8 of these lines also exhibited GFP expression in young adult cells. An additional 15 lines that did not have embryonic GFP+ hematopoietic tissue by microscopy, nevertheless exhibited GFP+ cells in young adults. RT-PCR analysis of purified GFP+ populations for expression of T and B cellspecific markers identified 18 lines in which T and/or B cells were fluorescently tagged at 6 weeks of age. As transposon insertion is expected to cause gene disruption, these lines can be used to assess the requirement for the disrupted genes in immune cell development. Focusing on the lines with embryonic GFP+ hematopoietic tissue, we identified three lines in which homozygous mutants exhibited impaired T cell development at 6 days of age. In two of the lines we identified the disrupted genes, agtpbp1 and eps15L1. Morpholino-mediated knockdown of these genes mimicked the T cell defects in the corresponding mutant embryos, demonstrating the previously unrecognized, essential roles of agtpbp1 and eps15L1in T cell development.
Stability of periodic stationary solutions of scalar conservation laws with space-periodic flux
Creators: name: Dalibard, Anne-Laure
Publisher: name: arXiv
Year: 2009
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35B35, 35B40, 35B27

description: This article investigates the long-time behaviour of parabolic scalar conservation laws of the type $\partial_t u + \mathrm{div}_yA(y,u) - Δ_y u=0$, where $y\in\mathbb R^N$ and the flux $A$ is periodic in $y$. More specifically, we consider the case when the initial data is an $L^1$ disturbance of a stationary periodic solution. We show, under polynomial growth assumptions on the flux, that the difference between $u$ and the stationary solution vanishes for large times in $L^1$ norm. The proof uses a self-similar change of variables which is well-suited for the analysis of the long time behaviour of parabolic equations. Then, convergence in self-similar variables follows from arguments from dynamical systems theory. One crucial point is to obtain compactness in $L^1$ on the family of rescaled solutions; this is achieved by deriving uniform bounds in weighted $L^2$ spaces.
description: 37 pages
Euchromiusini Léger, Landry & Nuss 2019
Creators: name: Landry, Bernard
name: Léger, Théo
name: Nuss, Matthias
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Crambidae

description: (b) EUCHROMIUSINI Léger, Landry & Nuss, 2019 (spelling emended in ruling in (1) above),
type genus: Euchromius Guenée, 1845; and
description: Published as part of Landry, Bernard, Léger, Théo & Nuss, Matthias, 2020, Case 3819 - Euchromiini Léger, Landry & amp; Nuss, 2019 (Insecta, Lepidoptera, Crambidae) and Euchromiinae Butler, 1876 (Insecta, Lepidoptera, Erebidae): proposed resolution of homonymy by emending the former to Euchromiusini, pp. 83 in Bulletin of Zoological Nomenclature 77 (1) on page 84, DOI: 10.21805/bzn.v77.a027, http://zenodo.org/record/15085591
Uniform spin chain physics arising from NCN bridges in CuNCN: surprises on the way from copper oxides to their nitride analogs
Creators: name: Tsirlin, Alexander A.
name: Rosner, Helge
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report on the unexpected uniform spin chain physics in CuNCN, the insulating nitride analog of copper oxides. Based on full-potential band structure calculations, we derive the relevant microscopic parameters, estimate individual exchange couplings, and establish a realistic spin model of this compound. The structure of CuNCN contains chains of edge-sharing CuN(4) squares. As a surprise, in contrast to analogous [CuO(2)] chains in "edge-sharing" cuprates, the leading magnetic interactions J ~ 2500 K run perpendicular to the structural [CuN(2)] chains via bridging NCN groups. The resulting spin model of a uniform chain is in agreement with the experimentally observed temperature-independent magnetic susceptibility below 300 K. The nearest-neighbor and next-nearest-neighbor interactions along the structural [CuN(2)] chains are J(1) ~ -500 K and J(2) ~ 100 K, respectively. Despite the frustrating nature of J(1) and J(2), we assign the anomaly at 70 K to long-range magnetic ordering, which is likely collinear with antiparallel and parallel arrangement of spins along the 'c' and 'a' directions, respectively. The pronounced one-dimensionality of the spin system should lead to a reduction in the ordered moment and to a suppression of the transition anomaly in the specific heat, thus impeding the experimental observation of the long-range ordering. Our results suggest CuNCN as a promising material for ballistic heat transport within spin chains, while the sizable bandwidth W ~ 3 eV may lead to a metal-insulator transition and other exotic properties under high pressure.
description: 10 pages, 5 figures. Submitted to Phys. Rev. B
A Day of Archaeology at Mission Escambe
Creators: name: Worth, John
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Archaeology From Indoors - A Day in the Life of a Small Unit
Creators: name: Jones, Matthew
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Edge-terminated molybdenum disulfide with a 9.4-Å interlayer spacing for electrochemical hydrogen production
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015

description: Layered molybdenum disulfide has demonstrated great promise as a low-cost alternative to platinum-based catalysts for electrochemical hydrogen production from water. Research effort on this material has focused mainly on synthesizing highly nanostructured molybdenum disulfide that allows the exposure of a large fraction of active edge sites. Here we report a promising microwave-assisted strategy for the synthesis of narrow molybdenum disulfide nanosheets with edge-terminated structure and a significantly expanded interlayer spacing, which exhibit striking kinetic metrics with onset potential of 103mV, Tafel slope of 49 mV per decade and exchange current density of 9.62 × 10-3 mA cm-2, performing among the best of current molybdenum disulfide catalysts. Besides benefits from the edge-terminated structure, the expanded interlayer distance with modified electronic structure is also responsible for the observed catalytic improvement, which suggests a potential way to design newly advanced molybdenum disulfide catalysts through modulating the interlayer distance.
Thermal Width of the $Υ$ at Large t' Hooft Coupling
Creators: name: Noronha, Jorge
name: Dumitru, Adrian
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We use the AdS/CFT correspondence to show that the heavy quark (static) potential in a strongly-coupled plasma develops an imaginary part at finite temperature. Thus, deeply bound heavy quarkonia states acquire a small nonzero thermal width when the t'Hooft coupling $λ=g^2 N_c \gg 1$ and the number of colors $N_c \to \infty$. In the dual gravity description, this imaginary contribution comes from thermal fluctuations around the bottom of the classical sagging string in the bulk that connects the heavy quarks located at the boundary. We predict a strong suppression of $Υ$'s in heavy-ion collisions and discuss how this may be used to estimate the initial temperature.
description: 9 pages, version to appear in Physical Review Letters