cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A complex network approach to stylometry
Creators: name: Amancio, Diego R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Statistical methods have been widely employed to study the fundamental properties of language. In recent years, methods from complex and dynamical systems proved useful to create several language models. Despite the large amount of studies devoted to represent texts with physical models, only a limited number of studies have shown how the properties of the underlying physical systems can be employed to improve the performance of natural language processing tasks. In this paper, I address this problem by devising complex networks methods that are able to improve the performance of current statistical methods. Using a fuzzy classification strategy, I show that the topological properties extracted from texts complement the traditional textual description. In several cases, the performance obtained with hybrid approaches outperformed the results obtained when only traditional or networked methods were used. Because the proposed model is generic, the framework devised here could be straightforwardly used to study similar textual applications where the topology plays a pivotal role in the description of the interacting agents.
description: PLoS ONE, 2015 (to appear)
Shear-strain and shear-stress fluctuations in generalized Gaussian ensemble simulations of isotropic elastic networks
Creators: name: Wittmer, J. P.
name: Kriuchevskyi, I.
name: Baschnagel, J.
name: Xu, H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Shear-strain and shear-stress correlations in isotropic elastic bodies are investigated both theoretically and numerically at either imposed mean shear-stress $τ$ ($λ=0$) or shear-strain $γ$ ($λ=1$) and for more general values of a dimensionless parameter $λ$ characterizing the generalized Gaussian ensemble. It allows to tune the strain fluctuations $μ_{γγ} \equiv βV \la δγ^2 \ra = (1-λ)/G_{eq}$ with $β$ being the inverse temperature, $V$ the volume, $γ$ the instantaneous strain and $G_{eq}$ the equilibrium shear modulus. Focusing on spring networks in two dimensions we show, e.g., for the stress fluctuations $μ_{ττ} \equiv βV \la δτ^2 \ra$ ($τ$ being the instantaneous stress) that $μ_{ττ} = μ_{A} - λG_{eq}$ with $μ_{A} = μ_{ττ}|_{λ=0}$ being the affine shear-elasticity. For the stress autocorrelation function $c_{ττ}(t) \equiv βV \la δτ(t) δτ(0) \ra$ this result is then seen (assuming a sufficiently slow shear-stress barostat) to generalize to $c_{ττ}(t) = G(t) - λ\Geq$ with $G(t)$ being the shear-stress relaxation modulus.
description: 17 pages, 15 figures
Martens-Mumford's Theorems for Brill-Noether Schemes arising from Very Ample Line Bundles
Creators: name: Bajravani, Ali
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: Tangent Spaces of V^r_d(L), Specific subschemes of C_d arising from various line bundles on C, are described. Then we proceed to prove Martense Theorem for these schemes, by which we determine curves C, which for some very ample line bundle L on C and some integers r and d with d\leq h^{0}(L)-2, the subscheme V^r_d(L) might attain its maximum dimension.
description: 10 pages
MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53
Creators: name: Johnsen, Steven A.
name: Wienken, Magdalena
name: Dobbelstein, Matthias
name: Moll, Ute M.
name: Dickmanns, Antje
name: Kassem, Moustapha
name: Zhang, Yanping
name: Najafova, Zeynab
name: Lozano, Guillermina
name: Zhang, Xin
name: Weiss, Miriam
name: Nemajerova, Alice
name: Karpiuk, Oleksandra
name: Kramer, Daniela
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: SummaryThe MDM2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. Here we report that MDM2 is required for the efficient generation of induced pluripotent stem cells (iPSCs) from murine embryonic fibroblasts, in the absence of p53. Similarly, MDM2 depletion in the context of p53 deficiency also promoted the differentiation of human mesenchymal stem cells and diminished clonogenic survival of cancer cells. Most of the MDM2-controlled genes also responded to the inactivation of the Polycomb Repressor Complex 2 (PRC2) and its catalytic component EZH2. MDM2 physically associated with EZH2 on chromatin, enhancing the trimethylation of histone 3 at lysine 27 and the ubiquitination of histone 2A at lysine 119 (H2AK119) at its target genes. Removing MDM2 simultaneously with the H2AK119 E3 ligase Ring1B/RNF2 further induced these genes and synthetically arrested cell proliferation. In conclusion, MDM2 supports the Polycomb-mediated repression of lineage-specific genes, independent of p53.
Asplenium auriculatum Sw., Kongl. Vetensk. Acad. Handl. 1817
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium auriculatum

description: Asplenium auriculatum Sw., Kongl. Vetensk. Acad. Handl. 1817 (1): 68. 1817.
 Range:— Antilles; Mexico to Bolivia (CH, CO, LP, SC) and Brazil.
 Ecology:— Common; mainly epiphytic, rarely on rocks, in humid forests; (200)500–2700(3000) m. Propagates vegetatively through root buds. In a study in La Paz, terrestrial individuals of the species were found mainly on rocky ridges with poorly developed, nutrient-poor soils (Jones et al. 2011).
 Notes:— Usually recognized by its fleshy, yellow-green blades and iridescent, golden brown, long-ciliate rhizome scales. Asplenium salicifolium has similar scales, but that species is larger in all aspects, and often has 2-forked veins. Asplenium auriculatum is very variable, with narrow to broad pinnae with obtuse to long-acuminate apices.
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
Asplenium auritum Sw., J. Bot. (Schrader 1800
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium auritum

description: Asplenium auritum Sw., J. Bot. (Schrader) 1800 (2): 52. 1801.
 Range:— Florida; Antilles; southern Mexico to Bolivia (BE, CO, LP, PA, SC) and Argentina; Africa, Madagascar, Mascarenes.
 Ecology:— Common; epiphytic, terrestrial, and saxicolous, in humid forests; to 2250 m. Young individuals are drought-resistant, whereas older ones are less so (Testo & Watkins 2012).
 Notes:— Closely related to, and sometimes considered conspecific with 2-pinnate A. cuspidatum. The most deeply cut specimens of A. auritum approach that species but differ by having more strongly winged rachises and a thicker blade texture. A detailed biosystematic study of the complex, also involving A. fragrans in Bolivia, is needed. There are also a number of related, extralimital species with 32 globose, unreduced spores per sporangium (e.g., A. monodon Liebm., A. sphaerosporum A.R.Sm.) rather than the usual 64, suggesting an apogamous life cycle (Mickel & Smith 2004, Gabancho et al. 2010). Plants with 32 spores per sporangium in this group have not yet been recorded from Bolivia, but should be looked for.
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
Clustering of Local Group distances: publication bias or correlated measurements? III. The Small Magellanic Cloud
Creators: name: de Grijs, Richard
name: Bono, Giuseppe
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Aiming at providing a firm mean distance estimate to the Small Magellanic Cloud (SMC), and thus to place it within the internally consistent Local Group distance framework we recently established, we compiled the current-largest database of published distance estimates to the galaxy. Based on careful statistical analysis, we derive mean distance estimates to the SMC using eclipsing binary systems, variable stars, stellar population tracers, and star cluster properties. Their weighted mean leads to a final recommendation for the mean SMC distance of $(m-M)_0^{\rm SMC} = 18.96 \pm 0.02$ mag, where the uncertainty represents the formal error. Systematic effects related to lingering uncertainties in extinction corrections, our physical understanding of the stellar tracers used, and the SMC's complex geometry---including its significant line-of-sight depth, its irregular appearance which renders definition of the galaxy's center uncertain, as well as its high inclination and possibly warped disk---may contribute additional uncertainties possibly exceeding 0.15--0.20 mag.
description: 17 pages, 2 figures (emulateapj format); AJ, in press
Visualizing the Path of DNA through Proteins Using DREEM Imaging
Creators: name: Wang, Hong
name: Wu, Dong
name: Li, Zimeng M.
name: Kaur, Parminder
name: Bradford, Kira C.
name: Erie, Dorothy A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Many cellular functions require the assembly of multiprotein-DNA complexes. A growing area of structural biology aims to characterize these dynamic structures by combining atomic-resolution crystal structures with lower-resolution data from techniques that provide distributions of species, such as small-angle X-ray scattering, electron microscopy, and atomic force microscopy (AFM). A significant limitation in these combinatorial methods is localization of the DNA within the multiprotein complex. Here, we combine AFM with an electrostatic force microscopy (EFM) method to develop an exquisitely sensitive dual-resonance-frequency-enhanced EFM (DREEM) capable of resolving DNA within protein-DNA complexes. Imaging of nucleosomes and DNA mismatch repair complexes demonstrates that DREEM can reveal both the path of the DNA wrapping around histones and the path of DNA as it passes through both single proteins and multiprotein complexes. Finally, DREEM imaging requires only minor modifications of many existing commercial AFMs, making the technique readily available.
Asplenium ayopayensis M. Kessler & A. R. Sm., Candollea
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium ayopayensis

description: Asplenium ayopayensis M.Kessler & A.R.Sm., Candollea 61: 306. 2006.
 Range:— Endemic to Bolivia (CO, LP).
 Ecology:— Rare; terrestrial, on rocks, and epiphytic in cloud forests; 2350–3600 m.
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development
Creators: name: Shamim, Muhammad Saad
name: Bassik, Michael C.
name: Phanstiel, Douglas H.
name: Aiden, Erez Lieberman
name: Snyder, Michael P.
name: Machol, Ido
name: Hess, Gaelen T.
name: Love, Michael I.
name: Van Bortle, Kevin
name: Spacek, Damek
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The three-dimensional arrangement of the human genome comprises a complex network of structural and regulatory chromatin loops important for coordinating changes in transcription during human development. To better understand the mechanisms underlying context-specific 3D chromatin structure and transcription during cellular differentiation, we generated comprehensive in situ Hi-C maps of DNA loops during human monocyte-to-macrophage differentiation. We demonstrate that dynamic looping events are regulatory rather than structural in nature and uncover widespread coordination of dynamic enhancer activity at preformed and acquired DNA loops. Enhancer-bound loop formation and enhancer-activation of preformed loops represent two distinct modes of regulation that together form multi-loop activation hubs at key macrophage genes. Activation hubs connect 3.4 enhancers per promoter and exhibit a strong enrichment for Activator Protein 1 (AP-1) binding events, suggesting multi-loop activation hubs driven by cell-type specific transcription factors may represent an important class of regulatory chromatin structures for the spatiotemporal control of transcription.
title: Microstructural Study of MgB₂ in the LiBH₄-MgH₂ Composite by Using TEM
Creators: name: Jin, Ou
name: Shang, Yuanyuan
name: Huang, Xiaohui
name: Mu, Xiaoke
name: Szabó, Dorothée Vinga
name: Le, Thi Thu
name: Wagner, Stefan
name: Kübel, Christian
name: Pistidda, Claudio
name: Pundt, Astrid
Publisher: name: MDPI
Year: 2022

description: The hampered kinetics of reactive hydride composites (RHCs) in hydrogen storage and release, which limits their use for extensive applications in hydrogen storage S1and energy conversion, can be improved using additives. However, the mechanism of the kinetic restriction and the additive effect on promoting the kinetics have remained unclear. These uncertainties are addressed by utilizing versatile transmission electron microscopy (TEM) on the LiBH₄-MgH₂ composite under the influence of the 3TiCl₃·AlCl₃ additives. The formation of the MgB₂ phase, as the rate-limiting step, is emphatically studied. According to the observations, the heterogeneous nucleation of MgB₂ relies on different nucleation centers (Mg or TiB₂ and AlB₂). The varied nucleation and growth of MgB₂ are related to the in-plane strain energy density at the interface, resulting from the atomic misfit between MgB₂ and its nucleation centers. This leads to distinct MgB₂ morphologies (bars and platelets) and different performances in the dehydrogenation kinetics of LiBH₄-MgH₂. It was found that the formation of numerous MgB₂ platelets is regarded as the origin of the kinetic improvement. Therefore, to promote dehydrogenation kinetics in comparable RHC systems for hydrogen storage, it is suggested to select additives delivering a small atomic misfit.
Propagation of correlations in Local Random Quantum Circuits
Creators: name: Santra, Siddhartha
name: Balu, Radhakrishnan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We derive a dynamical bound on the propagation of correlations in local random quantum circuits - lattice spin systems where piecewise quantum operations - in space and time - occur with classical probabilities. Correlations are quantified by the Frobenius norm of the commutator of two positive operators acting on space-like separated local Hilbert spaces. For times $t=O(L)$ correlations spread to distances $\mathcal{D}=t$ growing, at best, diffusively for any distance within that radius with extensively suppressed distance dependent corrections whereas for $t=o(L^2)$ all parts of the system get almost equally correlated with exponentially suppressed distance dependent corrections and approach the maximum amount of correlations that may be established asymptotically.
description: 7 pages, 5 figures. Updated abstract
skelesim : an extensible, general framework for population genetic simulation in R
Creators: name: Strand, Allan E.
name: Archer, Frederick I.
name: Hoban, Sean M.
name: DePrenger-Levin, Michelle E.
name: Liggins, Libby
name: Parobek, Christian M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Simulations are a key tool in molecular ecology for inference and forecasting, as well as for evaluating new methods. Due to growing computational power and a diversity of software with different capabilities, simulations are becoming increasingly powerful and useful. However, the widespread use of simulations by geneticists and ecologists is hindered by difficulties in understanding these softwares’ complex capabilities, composing code and input files, a daunting bioinformatics barrier, and a steep conceptual learning curve. skeleSim (an R package) guides users in choosing appropriate simulations, setting parameters, calculating genetic summary statistics, and organizing data output, in a reproducible pipeline within the R environment. skeleSim is designed to be an extensible framework that can ‘wrap’ around any simulation software (inside or outside the R environment) and be extended to calculate and graph any genetic summary statistics. Currently, skeleSim implements coalescent and forward-time models available in the fastsimcoal2 and rmetasim simulation engines to produce null distributions for multiple population genetic statistics and marker types, under a variety of demographic conditions. skeleSim is intended to make simulations easier while still allowing full model complexity to ensure that simulations play a fundamental role in molecular ecology investigations. skeleSim can also serve as a teaching tool: demonstrating the outcomes of stochastic population genetic processes; teaching general concepts of simulations; and providing an introduction to the R environment with a user-friendly graphical user interface (using shiny).
Asplenium bangii Hieron., Hedwigia
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium bangii

description: Asplenium bangii Hieron., Hedwigia 60: 245. 1918.
 Range:— Peru, Bolivia (BE, CH, LP, SC, TA); southeastern Brazil and adjacent Paraguay and Argentina.
 Ecology:— Common; terrestrial, rarely epiphytic or on rocks, in humid and semihumid forests; (250)450– 2150(2600) m.
 Notes:— Differs from A. harpeodes in having subentire to crenulate pinna margins (vs. deeply serrate), smaller pinnae (1.2–2.2(2.5) vs. 2.5–9 cm long), and shorter (1.5–3 vs. 4–10 mm long) rhizome scales with attenuate (vs. with long, tortuous, unicostate) tips. The occasional occurrence of intermediate specimens suggests hybridization with A. discrepans and perhaps also with A. claussenii.
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
A Model for the Development of Leadership Competencies Through Participation in Extra-Curricular Activities for Undergraduate Music Students in Southern Sichuan, China
Creators: name: Luo, Jian
Publisher: name: DR.KEN Institute of Academic Development and Promotion
Year: 2022
Subjects: Student Leadership
Extra-curricular Activities
Music Students

description: International Journal of Sociologies and Anthropologies Science Reviews, 2, 4, 89-102
Neutrino Masses and Deviation from Tri-bimaximal mixing in Δ(27) model with Inverse Seesaw Mechanism
Creators: name: Abbas, M.
name: Khalil, S.
name: Rashed, A.
name: Sil, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a scheme, based on Δ(27) flavor symmetry and supplemented by other discrete symmetries and inverse seesaw mechanism, where both the light neutrino masses and the deviation from tri-bimaximal mixing matrix can be linked to the source of lepton number violation. The hierarchies of the charged leptons are explained. We find that the quark masses including their hierarchies and the mixing can also be constructed in a similar way.
description: 6 pages, 2 figures
Linkage and related analyses of Barrett's esophagus and its associated adenocarcinomas
Creators: name: Iyer, Prasad G.
name: Guda, Kishore
name: Brock, Wendy
name: Barnholtz-Sloan, Jill S.
name: Shaheen, Nicholas J.
name: Markowitz, Sanford
name: Mittal, Sumeet K.
name: Elston, Robert
name: Wang, Jean S.
name: Falk, Gary W.
name: Chak, Amitabh
name: Sun, Xiangqing
name: Grady, William M.
name: Abrams, Julian A.
name: Willis, Joseph E.
name: Chandar, Apoorva
name: Canto, Marcia I.
name: Faulx, Ashley
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: 4
Hyperscaling at the spin density wave quantum critical point in two dimensional metals
Creators: name: Patel, Aavishkar A.
name: Strack, Philipp
name: Sachdev, Subir
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Gases (cond-mat.quant-gas)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The hyperscaling property implies that spatially isotropic critical quantum states in $d$ spatial dimensions have a specific heat which scales with temperature as $T^{d/z}$, and an optical conductivity which scales with frequency as $ω^{(d-2)/z}$ for $ω\gg T$, where $z$ is the dynamic critical exponent. We examine the spin-density-wave critical fixed point of metals in $d=2$ found by Sur and Lee (Phys. Rev. B 91, 125136 (2015)) in an expansion in $ε= 3-d$. We find that the contributions of the "hot spots" on the Fermi surface to the optical conductivity and specific heat obey hyperscaling (up to logarithms), and agree with the results of the large $N$ analysis of the optical conductivity by Hartnoll et al. (Phys. Rev. B 84, 125115 (2011)). With a small bare velocity of the boson associated with the spin density wave order, there is an intermediate energy regime where hyperscaling is violated with $d \rightarrow d_t$, where $d_t = 1$ is the number of dimensions transverse to the Fermi surface. We also present a Boltzmann equation analysis which indicates that the hot spot contribution to the DC conductivity has the same scaling as the optical conductivity, with $T$ replacing $ω$.
description: 46 pages, 5 figures, To appear in Phys. Rev. B
title: Τρισδιάστατη αριθμητική διερεύνηση επίδρασης συστήματος ασυνεχειών στην αντοχή στύλου σε υπόγεια εκμετάλλευση
Creators: name: Τσιρεκας Αθανασιος
Publisher: name: Technical University of Crete
Year: 2023

description: Σκοπός της παρούσας διπλωματικής εργασίας είναι να μελετηθούν οι παράμετροι που επηρεάζουν την αντοχή των στύλων και κατ’ επέκταση την ασφάλεια των υπογείων έργων. Έτσι, διερευνά τον ρόλο ανάπτυξης των ασυνεχειών που βρίσκονται εντός της δομής του πετρώματος και μπορούν να επηρεάσουν την αντοχή του αναλόγως την γωνία στην οποία αναπτύσσονται.
Κατά την κατασκευή ενός υπογείου έργου, οι ήδη υπάρχουσες τάσεις ανακατανέμονται, ειδικά στα σημεία  που υπάρχουν εκσκαφές. Στην μέθοδο θαλάμων και στύλων αυτή η ανακατανομή των τάσεων έχει ως αποτέλεσμα την επιβάρυνση των στύλων υποστήριξης. Γενικά, οι τάσεις και οι μετατοπίσεις σε αυτές τις περιοχές αποκλίνουν από την Θεωρία της γραμμικής Ελαστικότητας , έτσι ανάλογα με το είδος του γεωϋλικού μπορούν να δημιουργηθούν φαινόμενα όπως η δημιουργία ρωγμών, είτε η δημιουργία πλαστικής ζώνης στα σύνορα της εκσκαφής. Ίσως από τις πιο αποτελεσματικές μεθόδους εύρεσης λύσεων κλειστής μορφής προβλημάτων, η οποία βασίζεται στην έκφραση των τάσεων και των μετατοπίσεων, είναι η χρήση αριθμητικών μεθόδων, όπως των πεπερασμένων στοιχείων.
Στην παρούσα διπλωματική εργασία διερευνάται η επίλυση τέτοιους είδους προβλήματος με κατανομή των τάσεων και των μετατοπίσεων γύρω από υπόγειο άνοιγμα, το οποίο έχει υποβαθμιστεί ήδη από την ύπαρξη ασυνεχειών. Θα εξεταστεί επομένως η επίδραση ασυνεχειών στην ευστάθεια στύλου υποστήριξης υπόγειας εκμετάλλευσης. Τα αποτελέσματα που προέκυψαν αποδεικνύουν πως τόσο οι ασυνέχειες που αναπτύσσονται κατακόρυφα κατά τον άξονα x, όσο και αυτές που δημιουργούν το σύστημα το οποίο αποτελείται από δύο ασυνέχειες τοποθετημένες τυχαία στον χώρο σε αντίθετες όμως κατευθύνσεις οδηγούν σε αστοχία του στύλου. Τέλος η επίλυση οδηγεί στο εξής συμπέρασμα  ότι η γωνία τριβής είναι πολύ σημαντικός γεωτεχνικός παράγοντας. Το γεγονός αυτό είναι φυσιολογικό καθώς, δεν υπάρχουν οι απαιτούμενες γωνίες μεταξύ των κόκκων του πετρώματος ώστε να αντισταθούν στην δύναμη που τους ασκείται και να μην ολισθήσουν μεταξύ τους.
title: Assessing Resource Efficiency of City Neighbourhoods: A Methodological Framework for Structuring and Practical Application of Indicators in Urban Planning
Creators: name: Schebek, Liselotte
name: Lützkendorf, Thomas
Publisher: name: MDPI
Year: 2022

description: Today, changing framework conditions of living and working in cities drive urban planning processes for refurbishment, notably at the level of neighbourhoods, and provide a window of opportunity to enhance resource efficiency and sustainable urban development. Indicators, as part of sustainability assessment methods, may support the identification of the most beneficial planning alternatives or the selection of measures. However, the fact that a multitude of indicators are proposed in the literature discourages their actual use and hampers a sound application for decision support. To tackle these challenges, a manual has been developed proposing a framework for the use of indicators in urban planning. In this contribution, the theoretical foundations of the proposed framework are analysed. A conceptual outline of the framework is presented, which as its core has a typology of indicators, and its embedding in urban planning processes is discussed. The framework combines a theoretically concise unifying structure with a flexible practical approach for application in diverse areas of resource efficiency. Thus, it shall enhance transparency as well as comparability in the use of indicators, foster communication between stakeholders and in the long run support the application of indicators and use of sustainability assessment methods as regular parts of urban planning.
Cognitive endpoints for therapy development for neuronopathic mucopolysaccharidoses: Results of a consensus procedure
Creators: name: Kearney, Shauna
name: Semrud-Clikeman, Margaret
name: Giugliani, Roberto
name: Muenzer, Joseph
name: Jones, Simon
name: Wijburg, Frits A.
name: Escolar, Maria L.
name: Janzen, Darren
name: Harmatz, Paul
name: Hogan, Melissa
name: van der Lee, Johanna H.
name: Shapiro, Elsa
name: Morton, Jonathan
name: Yu, Zi-fan
name: Rust, Stewart
name: Ebbink, Berendine Johanne
name: Clarke, Lorne
name: Adams, Heather R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: AbstractThe design and conduct of clinical studies to evaluate the effects of novel therapies on central nervous system manifestations in children with neuronopathic mucopolysaccharidoses is challenging. Owing to the rarity of these disorders, multinational studies are often needed to recruit enough patients to provide meaningful data and statistical power. This can make the consistent collection of reliable data across study sites difficult. To address these challenges, an International MPS Consensus Conference for Cognitive Endpoints was convened to discuss approaches for evaluating cognitive and adaptive function in patients with mucopolysaccharidoses. The goal was to develop a consensus on best practice for the design and conduct of clinical studies investigating novel therapies for these conditions, with particular focus on the most appropriate outcome measures for cognitive function and adaptive behavior. The outcomes from the consensus panel discussion are reported here.
Asplenium bolivianum M. Kessler & A. R. Sm., Candollea
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium bolivianum

description: Asplenium bolivianum M.Kessler & A.R.Sm., Candollea 61: 307. 2006.
 Range:— Endemic to Bolivia (CO, LP).
 Ecology:— Rare; terrestrial in evergreen, but fairly dry montane forests of Podocarpus L’Her. ex Pers. and Weinmannia L.; 2500–2900 m.
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
Ex Vivo and In Vivo Noninvasive Imaging of Epidermal Growth Factor Receptor Inhibition on Colon Tumorigenesis Using Activatable Near-Infrared Fluorescent Probes
Creators: name: Blue, Randall E.
name: Lund, Pauline K.
name: Moorefield, Emily
name: Ding, Shengli
name: Yuan, Hong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Near-infrared fluorescence (NIRF) imaging combined with enzyme-activatable NIRF probes has yielded promising results in cancer detection.
Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States
Creators: name: Doolub, Gemina
name: Kobo, Ofer
name: Sharma, Garima
name: Paul, Timir K
name: Diaz-Arocutipa, Carlos
name: Ullah, Waqas
name: Myint, Phyo K
name: Mamas, Mamas
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: A significant proportion of the world’s population lives with physical disability (PD) requiring healthcare services. Risk factors for cardiovascular disease (CVD) such as hypertension and diabetes are more prevalent among patients with PD. Our study compares outcomes following acute myocardial infarction (AMI) between patients with preexisting PD and those without, using the National Inpatient Sample (NIS). We analyzed all adult inpatients having a diagnosis of AMI from 2015 to 2018. The main outcome measured was in-hospital all-cause mortality. Of 2,674,524 patients admitted with AMI, 5% had PD. Patients in the PD group were found to have higher mortality (aOR 1.13, CI 1.1–1.15 p < 0.001), with the musculoskeletal group showing the highest mortality. Patients with PD received lower rates of percutaneous coronary intervention (aOR 0.65, CI 0.64–0.66, <0.001), compared to the non-PD group, with the musculoskeletal group having the lowest rates of intervention. A diagnosis of PD was independently associated with significantly increased mortality following AMI. The prognostic impact of disability correlates with the nature of the disability, with musculoskeletal disability being associated with the worst mortality outcomes. Finally, patients with any type of PD are less likely to be offered invasive cardiac management following their AMI.
The Sloan Digital Sky Survey Reverberation Mapping Project: Ensemble Spectroscopic Variability of Quasar Broad Emission Lines
Creators: name: Sun, Mouyuan
name: Trump, Jonathan R.
name: Shen, Yue
name: Brandt, W. N.
name: Dawson, Kyle
name: Denney, Kelly D.
name: Hall, Patrick B.
name: Ho, Luis C.
name: Horne, Keith
name: Jiang, Linhua
name: Richards, Gordon T.
name: Schneider, Donald P.
name: Bizyaev, Dmitry
name: Kinemuchi, Karen
name: Oravetz, Daniel
name: Pan, Kaike
name: Simmons, Audrey
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We explore the variability of quasars in the MgII and Hbeta broad emission lines and UV/optical continuum emission using the Sloan Digital Sky Survey Reverberation Mapping project (SDSS-RM). This is the largest spectroscopic study of quasar variability to date: our study includes 29 spectroscopic epochs from SDSS-RM over $6$ months, containing 357 quasars with MgII and 41 quasars with Hbeta . On longer timescales, the study is also supplemented with two-epoch data from SDSS-I/II. The SDSS-I/II data include an additional $2854$ quasars with MgII and 572 quasars with Hbeta. The MgII emission line is significantly variable ($Δf/f$ 10% on 100-day timescales), a necessary prerequisite for its use for reverberation mapping studies. The data also confirm that continuum variability increases with timescale and decreases with luminosity, and the continuum light curves are consistent with a damped random-walk model on rest-frame timescales of $\gtrsim 5$ days. We compare the emission-line and continuum variability to investigate the structure of the broad-line region. Broad-line variability shows a shallower increase with timescale compared to the continuum emission, demonstrating that the broad-line transfer function is not a $δ$-function. Hbeta is more variable than MgII (roughly by a factor of $1.5$), suggesting different excitation mechanisms, optical depths and/or geometrical configuration for each emission line. The ensemble spectroscopic variability measurements enabled by the SDSS-RM project have important consequences for future studies of reverberation mapping and black hole mass estimation of $1
description: 20 pages, 25 figures. ApJ accepted: minor revisions following referee report
Vision Helps Touch: Pseudo-Haptic Effects for Conveying Fabrics Properties
Creators: name: Ricci, Marina
name: Wijntjes, Maarten
name: Huisman, Gijs
name: Pont, Sylvia
Publisher: name: Zenodo
Year: 2023

description: This research investigates how elasticity and weight of fabrics can be conveyed through pseudo-haptic effects. Here, pseudo-haptics is delivered through interactive visualizations using ‘shoogles’ that simulate the real-life interaction of the hand with a fabric by altering the fabric movement at the click of the mouse, based on a variable control/display ratio (or gain value).
Asplenium cristatum Lam., Encycl.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium cristatum

description: Asplenium cristatum Lam., Encycl. 2(1): 310. 1786.
 Range:— Florida; Antilles; Mexico to Bolivia (CH, CO, LP, SC) and Brazil.
 Ecology:— Fairly common; terrestrial, rarely epiphytic or on rocks, 250–1800 m (to 2400 m elsewhere).
 Notes:— Asplenium haenkeanum (C.Presl) Hieron., from Peru, may occur in Bolivia. It differs from A. cristatum by 2-pinnate blades, linear blade outline (vs. elliptic to elliptic-ovate), 3–6 pairs of pinnules per pinna (vs. 7–14 pairs), by its saxicolous habit, and by its occurrence above 2900 m. Specimens of A. cristatum with unusually small ultimate segments may be confused with Asplenium divaricatum Kunze from central Peru, which has bicolorous rhizome scales.
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
Networks, Dynamic Factors, and the Volatility Analysis of High-Dimensional Financial Series
Creators: name: Barigozzi, Matteo
name: Hallin, Marc
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Finance (q-fin.ST)
subject: Methodology (stat.ME)
subject: FOS: Economics and business
subject: FOS: Computer and information sciences

description: We consider weighted directed networks for analysing, over the period 2000-2013, the interdependencies between volatilities of a large panel of stocks belonging to the S\&P100 index. In particular, we focus on the so-called {\it Long-Run Variance Decomposition Network} (LVDN), where the nodes are stocks, and the weight associated with edge $(i,j)$ represents the proportion of $h$-step-ahead forecast error variance of variable $i$ accounted for by variable $j$'s innovations. To overcome the curse of dimensionality, we decompose the panel into a component driven by few global, market-wide, factors, and an idiosyncratic one modelled by means of a sparse vector autoregression (VAR) model. Inversion of the VAR together with suitable identification restrictions, produces the estimated network, by means of which we can assess how {\it systemic} each firm is.~Our analysis demonstrates the prominent role of financial firms as sources of contagion, especially during the~2007-2008 crisis.
A novel regulator controls Clostridium difficile sporulation, motility and toxin production
Creators: name: McBride, Shonna M.
name: Tamayo, Rita
name: Edwards, Adrianne N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Clostridium difficile is an anaerobic pathogen that forms spores which promote survival in the environment and transmission to new hosts. The regulatory pathways by which C. difficile initiates spore formation are poorly understood. We identified two factors with limited similarity to the Rap sporulation proteins of other spore-forming bacteria. In this study, we show that disruption of the gene CD3668 reduces sporulation and increases toxin production and motility. This mutant was more virulent and exhibited increased toxin gene expression in the hamster model of infection. Based on these phenotypes, we have renamed this locus rstA, for regulator of sporulation and toxins. Our data demonstrate that RstA is a bifunctional protein that upregulates sporulation through an unidentified pathway and represses motility and toxin production by influencing sigD transcription. Conserved RstA orthologs are present in other pathogenic and industrial Clostridium species and may represent a key regulatory protein controlling clostridial sporulation.
title: Facing the Green Threat: A Water Flea’s Defenses against a Carnivorous Plant
Creators: name: Kruppert, Sebastian
name: Horstmann, Martin
name: Weiss, Linda C.
name: Konopka, Elena
name: Kubitza, Nadja
name: Poppinga, Simon
name: Westermeier, Anna S.
name: Speck, Thomas
name: Tollrian, Ralph
Publisher: name: MDPI
Year: 2022

description: Every ecosystem shows multiple levels of species interactions, which are often difficult to isolate and to classify regarding their specific nature. For most of the observed interactions, it comes down to either competition or consumption. The modes of consumption are various and defined by the nature of the consumed organism, e.g., carnivory, herbivory, as well as the extent of the consumption, e.g., grazing, parasitism. While the majority of consumers are animals, carnivorous plants can also pose a threat to arthropods. Water fleas of the family Daphniidae are keystone species in many lentic ecosystems. As most abundant filter feeders, they link the primary production to higher trophic levels. As a response to the high predatory pressures, water fleas have evolved various inducible defenses against animal predators. Here we show the first example, to our knowledge, in Ceriodaphnia dubia of such inducible defenses of an animal against a coexisting plant predator, i.e., the carnivorous bladderwort (Utricularia x neglecta Lehm, Lentibulariaceae). When the bladderwort is present, C. dubia shows changes in morphology, life history and behavior. While the morphological and behavioral adaptations improve C. dubia’s survival rate in the presence of this predator, the life-history parameters likely reflect trade-offs for the defense.
DIGITAL GAME-BASED LEARNING: An Innovative Approach in Teaching Science in a New Normal Setting
Creators: name: Cezar, Lloyd
Publisher: name: figshare
Year: 2022
Subjects: subject: 130303 Education Assessment and Evaluation
subject: FOS: Educational sciences

description: A quasi-experimental study, investigating the effectiveness of digital game-based learning lessons on the learners’ performance and engagement. Sixty Grade 9 learners of Iligan City National School of Fisheries participated in the study. Digital game-based learning lessons were developed using the RPG Maker MV software. A 30-item researcher-made performance test was utilized and adopted the 2014 NSSE engagement scale. The gathered data were analyzed and interpreted using mean, standard deviation, frequency, percentage, one- way analysis of covariance (ANCOVA), and independent paired t-test. The results revealed that the experimental group achieved higher scores in their academic performance test compared with the control group. The experimental group obtained a “Did Not Meet Expectations'' from pretest to “Very Satisfactory” level in their post-test academic performance; while, the control group obtained “Did Not Meet Expectations” in their pretest to “Fairly Satisfactory” in their post-test results. The findings showed a significant difference in the performance between the experimental group, and the control group in favor of the experimental group. Moreover, the study revealed that the students in the experimental group attained a higher mean score in their engagement compared with the students in the control group. The engagement level of the experimental group was in “High Engagement”; while the control group were in “Average Engagement”. There was a significant difference in the mean score between the experimental group and the control group, in favor of the experimental group.
Asplenium claussenii Hieron., Hedwigia
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium claussenii

description: Asplenium claussenii Hieron., Hedwigia 60: 241. 1918.
 Range:— Venezuela, Colombia; Bolivia (CH, LP, SC, TA) and northeastern Argentina; southeastern Brazil, Paraguay; probably more widespread.
 Ecology:— Fairly common; terrestrial in humid to semideciduous forests; (200) 450–2800 m.
 Notes:— Typically, this species has shorter pinnae than A. bangii and rudimentary proximal pinnae, but intermediate specimens occur. The species group including these two species, as well as A. argentinum, A. discrepans, and A. drepanophyllum, is in need of taxonomic revision.
 Asplenium argentinum Hieron., from northwestern Argentina, has been erroneously reported from Bolivia (Foster 1958) but should be looked for in the south of the country. It differs from A. claussenii by the larger pinnae (1.8–2.3 × 0.6–0.8 cm) that are conspicuously broader and often more trapeziform, the teeth of the serrate margins more conspicuous and deeply incised, and by occasionally forked basal basiscopic veins.
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
Asplenium cuneatum Lam., Encycl.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Aspleniaceae
Asplenium
Asplenium cuneatum

description: Asplenium cuneatum Lam., Encycl. 2(1): 309. 1786.
 Range:— Antilles; Guatemala to the Guianas, Bolivia (LP), and Brazil; Africa; Polynesia. The conspecificity of plants from the Paleotropics with those from the Neotropics needs further study.
 Ecology:— Uncommon; epiphytic, saxicolous, and terrestrial, often on palms, in humid forests; to 450 m (to 1100 m elsewhere).
description: Published as part of Kessler, Michael & Smith, Alan R., 2018, Prodromus of a fern flora for Bolivia. XXIX. Aspleniaceae, pp. 259-280 in Phytotaxa 344 (3) on pages 259-280, DOI: 10.11646/phytotaxa.344.3.6, http://zenodo.org/record/13720625
Novel sesquiterpene lactone analogues as potent anti-breast cancer agents
Creators: name: Saito, Yohei
name: Chen, Jo-Yu
name: Takeya, Munehisa
name: Shyur, Lie-Fen
name: Nakagawa-Goto, Kyoko
name: Cheng, Yu-Ting
name: Lee, Kuo-Hsiung
name: Lee, Wai-Leng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Triple-negative breast cancer (TNBC) is associated with high grade, metastatic phenotype, younger patient age, and poor prognosis. The discovery of an effective anti-TNBC agent has been a challenge in oncology. In this study, fifty-eight ester derivatives (DETDs) with a novel sesquiterpene dilactone skeleton were organically synthesized from a bioactive natural product deoxyelephantopin (DET). Among them, DETD-35 showed potent antiproliferative activities against a panel of breast cancer cell lines including TNBC cell line MDA-MB-231, without inhibiting normal mammary cells M10. DETD-35 exhibited a better effect than parental DET on inhibiting migration, invasion, and motility of MDA-MB-231 cells in a concentration-dependent manner. Comparative study of DETD-35, DET and chemotherapeutic drug paclitaxel (PTX) showed that PTX mainly caused a typical time-dependent G2/M cell-cycle arrest, while DETD-35 or DET treatment induced cell apoptosis. In vivo efficacy of DETD-35 was evaluated using a lung metastatic MDA-MB-231 xenograft mouse model. DETD-35 significantly suppressed metastatic pulmonary foci information along with the expression level of VEGF and COX-2 in SCID mice. DETD-35 also showed a synergistic antitumor effect with PTX and . This study suggests that the novel compound DETD-35 may have a potential to be further developed into a therapeutic or adjuvant agent for chemotherapy against metastatic TNBC.
Reverse-Shock in Tycho's Supernova Remnant
Creators: name: Lu, F. J.
name: Ge, M. Y.
name: Zheng, S. J.
name: Zhang, S. N.
name: Long, X.
name: Aschenbach, B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Thermal X-ray emission from young supernova remnants (SNRs) is usually dominated by the emission lines of the supernova (SN) ejecta, which are widely believed being crossed and thus heated by the inwards propagating reverse shock (RS). Previous works using imaging X-ray data have shown that the ejecta are heated by the RS by locating the peak emission region of the most recently ionized matter, which is found well separated towards the inside from the outermost boundary. Here we report the discovery of a systematic increase of the Sulfur (S) to Silicon (Si) K$α$ line flux ratio with radius in Tycho's SNR. This allows us, for the first time, to present continuous radial profiles of the ionization age and, furthermore, the elapsed ionization time since the onset of the ionization, which tells the propagation history of the ionization front into the SNR ejecta.
description: 22 pages, 8 figures, accepted by ApJ
Shear stress relaxation and ensemble transformation of shear stress autocorrelation functions revisited
Creators: name: Wittmer, J. P.
name: Xu, H.
name: Baschnagel, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We revisit the relation between the shear stress relaxation modulus $G(t)$, computed at finite shear strain $0 < γ\ll 1$, and the shear stress autocorrelation functions $C(t)|_γ$ and $C(t)|_τ$ computed, respectively, at imposed strain $γ$ and mean stress $τ$. Focusing on permanent isotropic spring networks it is shown theoretically and computationally that in general $G(t) = C(t)|_τ = C(t)|_γ + G_{eq}$ for $t > 0$ with $G_{eq}$ being the static equilibrium shear modulus. $G(t)$ and $C(t)|_γ$ thus must become different for solids and it is impossible to obtain $G_{eq}$ alone from $C(t)|_γ$ as often assumed. We comment briefly on self-assembled transient networks where $G_{eq}(f)$ must vanish for a finite scission-recombination frequency $f$. We argue that $G(t) = C(t)|_τ = C(t)|_γ$ should reveal an intermediate plateau set by the shear modulus $G_{eq}(f=0)$ of the quenched network.
description: 8 pages, 4 figures