cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Galeocerdo cuvier
Creators: name: White, William T.
name: Ko'Ou, Alfred
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Chondrichthyes
Carcharhiniformes
Carcharhinidae
Galeocerdo
Galeocerdo cuvier

description: Galeocerdo cuvier (Péron & Lesueur in Lesueur, 1822)
Tiger Shark
Squalus cuvier Péron & Lesueur in Lesueur, 1822: 351. No types known. Type locality: northwestern Australia.
Local synonymy: Galeocerdo cuvieri— Munro, 1958: 113 (Dyke Ackland Bay). Galeocerda cuvieri— Munro, 1967: 9, pl. 1, fig. 8 (New Guinea). Galeocerdo cuvier— Filewood, 1973: 4 (PNG); Allen et al., 2003: 112 (Milne Bay); Hamilton et al., 2009: 73 (northern Bismarck Archipelago); White et al., 2018: 182, figs (PNG).
PNG voucher material: (4 spec.) KFRS E.014 (dried jaws), ~ 1830 mm TL, near Idia Island, 15 mile west of Port Moresby, 3 Dec. 1963; KFRS E.055 (dried jaws), Ramu River mouth, 19 Jul. 1965; KFRS E.379 (dried jaws), ~ 2430 mm TL, north end of Yule Island, Central Province, 8 Nov. 1969; KFRS E.775 (dried jaws), no label, new registration number allocated Apr. 2017 (possibly = E.480, Tatana, Port Moresby, 12 Sep. 1975, which cannot be located).
Remarks: First recorded from PNG by Munro (1958) from Dyke Ackland Bay in Oro Province. Caught by longline fisheries and coastal fisheries in PNG. Previously placed in the family Carcharhinidae but differs in a number of key characteristics from other members of that family (including very long upper labial furrows reaching to level of eye, strong keels on caudal peduncle, an obvious spiracle, and embryonic connection not via a placental connection) and also differs at a molecular level (Naylor et al., unpubl. data).
description: Published as part of White, William T. & Ko'Ou, Alfred, 2018, An annotated checklist of the chondrichthyans of Papua New Guinea, pp. 1-82 in Zootaxa 4411 (1) on page 42, DOI: 10.11646/zootaxa.4411.1, http://zenodo.org/record/1221878
Procedural and substantive land management techniques of potential relevance for the New Jersey Pinelands: A report to the Pinelands Commission, Volume 2, organizational, structural, and procedural elements
Creators: name: Ross, Hardies
Publisher: name: No Publisher Supplied
Year: 1980

description: This is the second of a five-volume study prepared for the New Jersey Pinelands Commission by Ross, Hardies, O'Keefe, Babcock & Parsons. The purpose of the report is to describe and provide a preliminary analysis of land planning and management techniques which have been used, or proposed, in this and other countries. This report serves as a basis for later elements of the Ross, Hardies work program in which, following an additional data-gathering stage, Ross, Hardies will work with the Commission and its staff to narrow the range of planning and management techniques which merit the Commission's consideration and will, as its final work product, draft specific legislation and regulations,designed to achieve the goals and purposes of the New Jersey Pinelands Protection Act of 1979.In this volume, Ross, Hardies  present detailed descriptions of a number of state and regional land use programs for the purpose of illustrating the variety of organizational and procedural approaches that can be taken to regional land planning and management.
Procedural and substantive land management techniques of potential relevance for the New Jersey Pinelands: A report to the Pinelands Commission, Volume 1, introduction, summary, and analysis
Creators: name: Ross, Hardies
Publisher: name: No Publisher Supplied
Year: 1980

description: The contract between Ross, Hardies, O'Keefe, Babcock & Parsons and the Pinelands Commission requires Ross, Hardies under Tasks I and V of the Scope of Services, to provide the Commission with an analysis of procedural and substantive land management techniques currently in use in the United States and other countries which may provide models or lessons for the development of a land planning and management program for the New Jersey pine barrens. Volume 1 is an introduction to and a summary, and analysis of the report.
Critical areas study for the Pinelands
Creators: name: Dechert, Sandy
name: Gould, Deborah
Publisher: name: No Publisher Supplied
Year: 1980

description: This study on critical areas is part of a larger effort on the part of Rogers, Golden & Halpern to help coordinate scientific and land planning activities for the Pinelands Commission in developing regulatory standards and the Comprehensive Management Plan. The objective of the critical areas study is to develop and execute a method for establishing a ranked list of critical areas in the New Jersey Pinelands. The areas designated as critical should be acquired or protected.
Pinelands comprehensive management plan
Creators: name: New Jersey. Pinelands Commission.
Publisher: name: No Publisher Supplied
Year: 1980

description: The New Jersey Pinelands, a million-acre forest expanse in the midst of the country's most densely populated region, have finally been recognized as one of the nation's premier environmental treasures. For more than a year, the Pinelands Commission has been developing a strategy to preserve and protect the many qualities of this unique resource. The Comprehensive Management Plan is the result of that process. It is also the culmination of long-term efforts by private groups and individuals, as well as local, state and federal governments.
Drosophila eohydey Wasserman 1962
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Drosophila
Drosophila eohydey

description: eohydey Wasserman, 1962a: 73. Type locality: Colombia, Santander, Bucaramanga. HT M (USNM). NT Distr.: Honduras to Colombia (Magdalena (Santa Marta), Santander (Bucaramanga)). Refs.: Yoon, 1996: 36.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 726, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Eusphyra Gill 1862
Creators: name: White, William T.
name: Ko'Ou, Alfred
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Chondrichthyes
Carcharhiniformes
Sphyrnidae
Eusphyra

description: Genus Eusphyra Gill, 1862
Winghead Shark
Eusphyra Gill, 1862: 403. Type species: Zygaena blochii Cuvier, 1816, by original designation (and by monotypy).
description: Published as part of White, William T. & Ko'Ou, Alfred, 2018, An annotated checklist of the chondrichthyans of Papua New Guinea, pp. 1-82 in Zootaxa 4411 (1) on page 42, DOI: 10.11646/zootaxa.4411.1, http://zenodo.org/record/1221878
Inflammatory State of Macrophages and COPD Exacerbation
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Acute flare up of respiratory symptoms, or exacerbation, is the major cause of morbidity and mortality in Chronic Obstructive Pulmonary Disease (COPD). Infection due to microorganisms are thought to contribute to the development of COPD exacerbations. Immune cells that reside in the lung, including cells called alveolar macrophages (AM), play an important role in the defense against infections. In COPD, these AM are defective in their ability to clear pathogens or the cells that die in the lung in the aftermath of an infection. Interestingly, it remains unclear whether AM’s defective clearing abilities cause more frequent or severe exacerbations.

 In a pilot study, we reproduced the previously-reported defect in pathogen clearance and its association with severity of airflow obstruction in COPD. But we found no difference in AM’s ability to clear pathogens or cell debris between patients with and without exacerbation. In this research, we propose to examine the hypothesis that a different defect in AM, an imbalance in pro- and anti-inflammatory processes, is associated with the susceptibility to exacerbation in COPD patients. We will use state of the art approaches to analyze AM status and functionality and how that relates to the level of exacerbation. Furthermore, we will assess the gene expression changes in defective AM from COPD patients and identify potential biomarkers that could be therapeutically targeted. Therefore, results of this study would delineate the pathogenesis of COPD exacerbation and guide efforts to develop a new class of therapeutics based on AM biology.
Eusphyra blochii
Creators: name: White, William T.
name: Ko'Ou, Alfred
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Chondrichthyes
Carcharhiniformes
Sphyrnidae
Eusphyra
Eusphyra blochii

description: Eusphyra blochii (Cuvier, 1816)
Winghead Shark
Zygaena blochii Cuvier, 1816: 127. Holotype: ZMB 7835 (stuffed). Type locality: unknown; Fowler, 1941 thought type was from India.
Local synonymy: Eusphyra blochii— Filewood, 1973: 2 (PNG); Kailola, 1987: 21 (Ramu River mouth; Broken Water Bay; eastern Papua; Port Moresby; Yule Island; Orokolo Bay); White et al., 2018: 184, figs (PNG).
PNG voucher material: (23 spec.) CSIRO H 7612-01, female 410 mm TL, south of Kerema, Gulf of Papua, 8°1’12” S, 145°42’2.4” E, 13–14 m depth, 21 Jun. 2014; CSIRO H 7614-06, female 420 mm TL, CSIRO H 7614- 0 7, female 420 mm TL, south of Kerema, Gulf of Papua, 8°3’1.2” S, 145°45’7.2” E, 16–17 m depth, 20 Jun. 2014; CSIRO H 7615-02, female 410 mm TL, CSIRO H 7615-03, juvenile male 410 mm TL, south of Kerema, Gulf of Papua, 8°2’55.2” S, 145°43’30” E, 17 m depth, 20 Jun. 2014; CSIRO H 8000-01, female embryo 320 mm TL, CSIRO H 8000-02, female embryo 330 mm TL, CSIRO H 8000-03, female embryo 350 mm TL, south of Kerema, Gulf of Papua, 8°3.65’ S, 145°42.18’ E, 19 m depth, 2 Sep. 2015; CSIRO H 8166-01 (dried jaws and chondrocranium), female 670 mm TL, southwest of Kerema, Gulf of Papua, 8°4’ S, 145°38’ E, 14–15 m depth, 30 Nov. 2014; KFRS E.054A (dried jaws), KFRS E.054B (dried jaws), Ramu River mouth, Madang Province, 19 Jul. 1965; KFRS E.345A, female 293 mm TL, KFRS E.345B, juvenile male 290 mm TL, Kairuku, Yule Island, Nov. 1968; KFRS E.679, female 940 mm TL, Katatai, Daru, Western Province, 9°1’15.13” S, 143°20’30.59” E, 22 Oct. 2014; KFRS E.690, juvenile male 440 mm TL, south of Kerema, Gulf of Papua, 8°2’55.8” S, 145°44’57” E, 14–16 m depth, 19 Jun. 2014; KFRS E.703, juvenile male 400 mm TL, Freshwater Bay, Gulf of Papua, 8°6’39.6” S, 145°53’57” E, 15–19 m depth, 19 Jun. 2014; KFRS E.707, juvenile male 400 mm TL, south of Kerema, Gulf of Papua, 8°3’25.2” S, 145°43’3.6” E, 17–19 m depth, 19 Jun. 2014; KFRS E.709, juvenile male 410 mm TL, Freshwater Bay, Gulf of Papua, 8°5’24.6” S, 145°51’7.2” E, 13 m depth, 22 Jun. 2014; KFRS E.729, juvenile male 370 mm TL, Freshwater Bay, Gulf of Papua, 8°6’45.6” S, 145°50’49.8” E, 21–22 m depth, 13 Jun. 2014; KFRS E.742, male 650 mm TL, east of Fly River mouth, Gulf of Papua, 8°16’ S, 144°20’ E, 20–22 m depth, 6 Dec. 2014; KFRS E.795 (3 spec.), embryos 320–350 mm TL, south of Kerema, Gulf of Papua, 8°3.65’ S, 145°42.18’ E, 19 m depth, 2 Sep. 2015.
Remarks: First recorded from PNG by Filewood (1973) who commented that it was found in inshore muddy waters. Very common bycatch in the Gulf of Papua prawn trawl fishery and in coastal fisheries, particularly in the Western and Gulf Provinces.
description: Published as part of White, William T. & Ko'Ou, Alfred, 2018, An annotated checklist of the chondrichthyans of Papua New Guinea, pp. 1-82 in Zootaxa 4411 (1) on pages 42-43, DOI: 10.11646/zootaxa.4411.1, http://zenodo.org/record/1221878
An assessment of the birdlife of the Pinelands National Reserve/Pinelands area
Creators: name: Brady, Sharon Ann
Publisher: name: No Publisher Supplied
Year: 1980

description: The purpose of this report to the New Jersey Pineland Commission is to assess the birdlife of the region of New Jersey designated as the Pinelands National Reserve/Pinelends Area (hereafter PNR/PA). In doing so we have compiled all available information on abundance and on distribution by watershed and habitat or each species occurring regularly in the area. Our research has indicated certain habitats and certain specific sites that are of particular importance within the PNR/PA ecosystem. We have determined how various human-related environmental disturbances will influence birdlife and have recommended land-use management techniques to prevent or mitigate undesirable effects.
Air quality assessment of the New Jersey Pinelands
Creators: name: New Jersey. Dept. Of Environmental Protection
Publisher: name: No Publisher Supplied
Year: 1980

description: The development of a Comprehensive Management Plan for the Pinelands must include an assessment of existing air quality in the Pinelands area and an understanding of the possible degradation of the air quality as a result of development and growth in and around the Pinelands. A thoughtful plan will attempt to minimize the air quality impact of development.This report is intended to aid the Pinelands Commission in the preparation of the Comprehensive Management Plan by describing existing air quality in the Pinelands (section 5.0), identifying sources of air pollution already in the Pinelands (section 6.0) and recommending land use plans which will minimize the air quality impact of development (section 7.0). Two major issues are identified and discussed. First, ozone is the only pollutant known to reach unhealthful levels in the Pinelands. The ozone is generated during the warmer months from pollutants emitted from a variety of sources but the most important source in the Pinelands is the automobile. The extent of traffic in, through and around the Pinelands is, therefore, an important issue to be addressed by the Plan. The second major issue is maintenance of the clean air existing in the Pinelands. All air pollutants, other than ozone, which have been measured in the Pinelands are observed to be at low levels relative to the national ambient air quality standards and to the levels observed in the surrounding urban areas. It should be a goal of the Plan to maintain these low air pollution levels in order to protect the plant and animal species indigenous to the Pinelands, and to maintain the good visibility essential to recreational use of the Pinelands.
Sphyrna Rafinesque 1810
Creators: name: White, William T.
name: Ko'Ou, Alfred
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Elasmobranchii
Carcharhiniformes
Carcharhinidae
Sphyrna

description: Genus Sphyrna Rafinesque, 1810a
Hammerhead Sharks
Sphyrna Rafinesque, 1810a: 60. Type species: Squalus zygaena Linnaeus, 1758, by subsequent designation (Bonaparte, 1838).
description: Published as part of White, William T. & Ko'Ou, Alfred, 2018, An annotated checklist of the chondrichthyans of Papua New Guinea, pp. 1-82 in Zootaxa 4411 (1) on page 43, DOI: 10.11646/zootaxa.4411.1, http://zenodo.org/record/1221878
Molecular Pathogenesis & Therapy for Critical Limb Ischemia
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The proposed study aims to seek novel treatment strategies for peripheral artery disease (PAD). PAD occurs when the arteries that supply blood to the arms and legs are blocked by plaque build-up, decreasing blood flow to the extremities. PAD affects more than 10 million Americans over the age of 65. Cigarette smoking increases the risk of developing PAD by 4-fold, and lowers the age of onset by 10 years. About 200,000 PAD patients develop to a more severe condition, critical limb ischemia (CLI), which can result in limb amputation or death. PAD is currently treated through surgical intervention, but complications and failures from these surgeries occur frequently. Further, many PAD patients are poor candidates for these interventions. Therefore, developing better treatment options for PAD is urgent. My lab studies therapeutic arteriogenesis, an innovative, non-invasive strategy to develop novel molecular therapies for PAD. To restore blood flow after artery blockage, small dormant arteries around the blockage must enlarge. Arteriogenesis, the ability to enlarge these dormant arteries, holds promise to rescue affected tissues. We have discovered that a gene encoding a protein on the surface of blood vessel wall cells can allow mice to recover from experimental arterial blockage better than mice without this gene. We will test the efficacy of this gene as a molecular stimulator for therapeutic arteriogenesis, particularly in old mice exposed to cigarette smoke. Using state-of-the-art techniques, we will test if this gene promotes dormant arteries around the blockage to acutely expand following arterial blockage, and then to grow larger to serve as long-term, durable, conduit artery replacements for the blocked artery. Determining the mechanism through which this gene enhances recovery from artery blockage will aid in our drug development effort to treat PAD. Finally, we will also test if the level of this gene is lower in amputated lower limbs from human CLI amputees compared to normal limbs from trauma amputees, paving the way for drug development. PAD and other cardio- and cerebrovascular diseases, such as heart attack and stroke, share the similar underlying cause of arterial narrowing and lack of blood flow. Results from this proposed work may have significant therapeutic implications for many tobacco-related diseases including heart attack and stroke.
SPORTSMANSHIP BEHAVIOUR OF MANAGERS AND ITS EFFECT ON EMPLOYEE COMMITMENT: A CASE STUDY OF PORT HARCOURT'S HOSPITALITY INDUSTRY.
Creators: name: Emmanuel Chinedu, Okoye
name: Amina Ngozi, Eze
Publisher: name: continental
Year: 2025
Subjects: : Managers' Sportsmanship Behaviour, Employee Commitment, Affective Commitment and Normative Commitment.

description: This study examines the relationship between managers’ sportsmanship behaviour and employee commitment in the hospitality sector in Port Harcourt, Nigeria. Employee commitment was assessed in terms of affective commitment and normative commitment. This research utilized a quasi-experimental and cross-sectional survey designs. The target population is 159 sample elements drawn from the four major hotels and restaurants in Port Harcourt, Nigeria. However, the accessible population was 124 respondents. The sample size (S) was determined based on the guidelines of census study technique which allow for the entire population (124) to be adopted as the sample. The study relied on primary source and secondary data sources. Data was analyzed using Sperman’s Rank Order Correlation Coefficient with the aid of SPSS. The findings of the study showed that workers' levels of affective and normative commitment were positively correlated with sportsmanship behaviour shown by their managers. It was recommended that; Managers should exhibit sportsmanship behaviour, which involves behaving ethically and respectfully towards their employees. This will create a positive work environment that fosters affective commitment among employees. Managers should strive to create a positive work environment that fosters teamwork, collaboration, and positivity. A positive work environment can lead to increased normative commitment among employees.
Drosophila fasciola Williston 1896
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Drosophila
Drosophila fasciola

description: fasciola Williston, 1896: 410. Type locality: St. Vincent and the Granadines, St. Vincent, windware side. LT M (BMNH). NT Distr.: West Indies, El Salvador to Guyana. Colombia (Magdalena (70 Km S Santa Marta). Refs.: Vilela, 1983: 10.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 726, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Fire Management Plan
Creators: name: Hughes, Joseph R.
Publisher: name: No Publisher Supplied
Year: 1979

description: This plan was prepared by the New Jersey Bureau of Forest Fire Management for the Pine lands Commission.The accompanying 'paper "Development in the Pine Barrens; A Design for Disaster" serves to expand understanding of fire management and wildfire control in the Pine Barrens Region. The paper outlines the basic issues to be considered, 'existing management techniques, alternatives, and areas requiring further study.The enclosed plan prescribes the methods and procedures whereby the desired fire management objectives wit I be accomplished.The major issues to be addressed are:I. The Protection of life and property In the Pine Barrens Region.2. The protection and perpetuation of the Pine Barrens Ecosystem through fire management techniques.
New Jersey Pinelands Forestry Report
Creators: name: New Jersey Bureau Of Forestry Management
Publisher: name: No Publisher Supplied
Year: 1980

description: Forests are an integral part of our environment and should be viewed as plant communities that provide many beneficial services, products, ru1d amenities to the inhabitants of the State. Foresters believe that the proper application of scientific forest management will conserve and protect the Pinelands for future generations. The traditional uses of Pinelands forests can be enhanced by managing the forest. Succession, past use, and abuse (especially wildfire) have shaped present conditions in the Pinelands. Any strategies developed to retain and enhance Pine lands conditions must coordinate successional trends, forest management principles and disturbances.This report discusses the benefits of forest land, Pinelands wood products, silviculture, forestry in the Pinelands, alternative forest management techniques, and forest-related issues in the Pinelands.
An assessment of the game mammals and birds and small mammals of the Pinelands
Creators: name: Penkala, Joseph M.
name: Hahn, Ernest P.
name: Sweger, Joseph G.
Publisher: name: No Publisher Supplied
Year: 1980

description: The game, furbearing and small mammal species of the Pinelands are a valuable resource to the region as well as the state as a whole. The existence of these species in the Pinelands of New Jersey provide a great deal of recreation and economic benefit to the residents of the state. In addition they are an intregal part of the ecosystem. A planned approach to human utilization of the Pinelands will assure the continued availability of these wildlife related values. As open space is lost in other areas of the state, the full potential of this resource in the Pinelands will become increasingly apparent. The maximization of wildlife oriented benefits can only be accomplished through habitat protection, active wildlife management and progressive management of human use of the resource. The utilization of the wildlife resource will not conflict with other economic, cultural, aesthetic and ecological factors identified as being valuable by the Pinelands legislation.
Sphyrna mokarran
Creators: name: White, William T.
name: Ko'Ou, Alfred
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Elasmobranchii
Carcharhiniformes
Carcharhinidae
Sphyrna
Sphyrna mokarran

description: Sphyrna mokarran (Rüppell, 1837)
Great Hammerhead
Zygaena mokarran Rüppell, 1837: 66, pl. 17 (fig. 3). Lectotype: SMF 3590 (stuffed); lectotype designation by Klausewitz (1960). Type locality: Massawa, Eritrea, Red Sea.
Local synonymy: Sphyrna tudes— Filewood, 1973: 2 (PNG). Sphyrna mokarran— Kailola, 1987: 21 (western Papua; Hall Sound; Port Moresby; Bootless Bay; Salamaua); White et al., 2018: 188, figs (PNG).
PNG voucher material: (2 spec.) KFRS E.176 (dried jaws), Tatana, Fairfax Harbour, Port Moresby, 7 Oct. 1965; KFRS E.259 (dried jaws), Kanudi Bay, Port Moresby, 4 Aug. 1966.
Remarks: First recorded from PNG by Filewood (1973) as S. tudes (= mokarran). Recorded from prawn trawl fishery bycatch and from coastal fisheries catches during recent surveys, but in low numbers.
description: Published as part of White, William T. & Ko'Ou, Alfred, 2018, An annotated checklist of the chondrichthyans of Papua New Guinea, pp. 1-82 in Zootaxa 4411 (1) on page 44, DOI: 10.11646/zootaxa.4411.1, http://zenodo.org/record/1221878
Salt Inducible Kinases (SIKs): Novel Regulators of Cardiomyocyte Plasticity
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tobacco use is a leading cause of cardiac related disease in the United States and a major contributor to the growing epidemic of heart failure. The 5-year survival rate upon diagnosis of heart failure is ~50%, yet despite this massive unmet medical need, current drugs and treatments for heart failure have limited effects in slowing or reversing disease progression. The development of novel and efficacious heart failure therapies is desperately needed but has been particularly challenging because of our incomplete understanding of the molecular mechanisms and underlying biology that drive the pathogenesis of disease. In this proposed study, I have identified a new family of proteins called Salt Inducible Kinases (SIKs) that may represent novel drug targets in heart failure. To date, no one has studied the role of these SIK proteins in the heart and how they may contribute to the development of heart failure. In my preliminary experiments, I have shown that using a drug that targets SIKs as well as genetic engineering to remove SIKs can prevent the harmful growth in heart cells during heart failure. However, harmful cell growth is only one aspect of this disease and as such, we need to better characterize the effects of blocking SIK function in the heart. This proposal serves to accomplish just that by using chemical and genetic approaches to determine what effect SIKs have on changing the DNA and RNA landscape during heart failure. I will also use a new genetic tool called CRISPR to delete SIKs in mice to see whether this intervention can protect mice from heart failure. If my proposed studies are successful, I will gain new fundamental knowledge about how SIKs drive the development and progression of heart failure. This will contribute to our overall understanding of the underlying biology that occurs in the heart during normal and disease states and may lay the groundwork for future development of novel targeted therapies for heart failure.
An inventory and assessment of prehistoric archaeological resources in the New Jersey Pinelands: Phase one of a regional predictive survey
Creators: name: Cavallo, John
name: Mounier, R. Alan
Publisher: name: No Publisher Supplied
Year: 1980

description: This report presents the preliminary findings of an archaeological survey of prehistoric aboriqinal sites in the New Jersey Pinelands. This study is an outgrowth of earlier research which set about to examine the relationships between site occurrence and environmental factors in an effort to identify any repetitive and predictabvle associations between the two (Cavallo 197e). Althouqh this work was originally designed as a piece of academic research in a portion of New Jersey which is virtually unknown archaeologically, it was recognized that the study would also hold promise for establishing procedures and policies for managing cultural resources in a region where these resources have come under stress from a wide range of development pressures. In the interest of promoting both theoretically relevant research and responsible cultural resource management, this study was jointly funded by a matching-grant from the New Jersey Department of Environmental Protection (Office of Historic Preservation) and matching funds from Monmouth College and the New Jersey Pinelands Commission.
Social and economic factors likely to influence Pinelands development
Creators: name: Associates, Alan Mallach
Publisher: name: No Publisher Supplied
Year: 1980

description: This report is devoted to a series of separate discussions of a number of social and economic factors or trends which, separately or together, are capable of influencing, potentially in a significant way, the course of development in and around the Pinelands region. In this report we focus on four such factors, the first two relatively specific and localized, the latter two more generalized, both in their impact and in the nature of the underlying factor: - retirement community development - casino development in Atlantic City- general economic trends affecting the region- trends in the cost and availability of energy
Drosophila franii Hunter 1988
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Drosophila
Drosophila franii

description: franii Hunter, 1988: 307. Type locality: Colombia, Monserrate in Bogotá, in the aqueduct watershed on the mountain. HT M (CAS). NT Distr.: Colombia (Bogota, D.C). Refs.: Hunter, 1992: 197.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 726, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Flavored tobacco initiation among youth and young adults
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tobacco products such as e-cigarettes and hookah are sold in thousands of flavors, which hide the harsh taste of tobacco and associate tobacco products with candy. In California, although the overall prevalence of cigarette smoking has continued to decline, use of e-cigarettes and other often-flavored products has increased. Disparities in tobacco use persist, in part due to high prevalence of menthol cigarette use among racial and ethnic minority smokers. In light of these patterns, the California Medical Association has noted that flavored tobacco may threaten the progress achieved by tobacco control in the state.

 While evidence is strong that young tobacco users use flavors more than older tobacco users and disparities exist in menthol cigarette use, less is known about the profile of young flavored tobacco users across products, and whether and to what extent flavors lead young people to try tobacco and become an established user. Across California, local governments are proposing and adopting “flavor bans” of all flavored tobacco products including menthol cigarettes. The impact of California flavor bans depends on how much flavors encourage tobacco use progression and relieve or worsen disparities. Accordingly, this project has two research goals: (1) identify sociodemographic, environmental, and behavioral characteristics that are associated with flavored tobacco initiation of youth and young adults, and (2) determine whether and to what extent initiation of tobacco use with a flavored product is related to subsequent tobacco use and nicotine exposure.

 This quantitative study will include youth (age: 12-17) and young adults (age: 18-24) from three waves (2013-2016) of the Population Assessment of Tobacco and Health (PATH) Study. The population-based longitudinal PATH study has information on flavored tobacco use for many products, chemically verified biomarkers of nicotine exposure for adults, and a large sample size necessary for subgroup analysis. Relationships will be tested using statistical techniques. Findings will illuminate how flavor bans will impact youth and young adult tobacco use and tobacco use disparities in California and will inform the development of local ordinances regulating menthol cigarettes and other flavored tobacco. Findings will be shared with community organizations, municipalities, and policy makers in the state.
Population trends and demand pressures in the Pinelands
Creators: name: Associates, Alan Mallach
Publisher: name: No Publisher Supplied
Year: 1980

description: The following report is prepared to provide an analytical basis for evaluating future population trends likely to affect demand pressures for development in the Pinelands area. Through the evaluation of population trends, including total numbers as well as salient characteristics, the report attempts to assess the future demand for housing in the Pinelands region. That, in turn, should be important as the most significant element in projecting future demand for land for development purposes in the region.
The effect of tobacco on oral mucosal renewal and regeneration
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The oral cavity is a dynamic environment in which cells must regularly handle bacterial, chemical, and physical insults. To cope with these stresses, the lining of the oral cavity is highly regenerative, with an average turnover of several days. However, the cellular and molecular mechanisms by which this regeneration is achieved are relatively unexplored, and little research has been done to identify stem or progenitor cells in the oral epithelium. An understanding of how stem and progenitor cells regenerate the oral epithelium is of great clinical importance, as there are many oral pathologies, such as mucositis and tobacco-induced cancer that likely involve defects in this process. In this study, we will lay the foundation for understanding how tissue homeostasis of the oral epithelium is maintained by stem and/or progenitor cells under normal and injury conditions.
Growth Shapers
Creators: name: Associates, Alan Mallach
Publisher: name: No Publisher Supplied
Year: 1980

description: This report attempts to inventory certain key physical or developmental features in and around the Pinelands capable of influencing the extent and direction of future growth in the Pinelands region. As such, it is a parallel to the report Social and Economic Factors Capable of Influencing Pinelands Development; in this report, the factors discussed are physical, with explicit locational features. In the other, the factors are demographic or economic, or, in many cases, more generalized and speculative.
Role of DNA damage in Pulmonary Artery Hypertension
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Pulmonary Arterial Hypertension (PAH) is a lethal disease of the pulmonary vasculature characterized by progressive remodeling of distal pulmonary arteries. If untreated, the median survival of patients with PAH is 2.8 years. A recent study found a higher prevalence of smokers among male patients compared to healthy controls, and a higher exposure to environmental tobacco smoke among women patients, suggesting that both active and environmental tobacco smoke exposure are risk factors of PAH. In this application, we will study the link between tobacco smoke and PAH. We hypothesize that PAH is triggered by a combination of two hits: (i) a “genotoxic” (genome-damaging) effect caused by tobacco smoke exposure and (ii) a “genetic” effect due to mutations in a PAH-linked gene, BMPR2, which disrupt DNA repair, leading to accumulation of DNA damage and genome instability. Upon successful execution of this project, we will be able to elucidate how tobacco smoke synergizes with the genetic background of some individuals to trigger PAH. We will also provide novel drug targets for anti-PAH therapy.
Pristis Linck 1790
Creators: name: White, William T.
name: Ko'Ou, Alfred
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Chondrichthyes
Pristiformes
Pristidae
Pristis

description: Genus Pristis Linck, 1790
Sawfishes
Pristis Linck, 1790: 31. Type species: Squalus pristis Linnaeus 1758. Type by monotypy (also by absolute tautonymy).
description: Published as part of White, William T. & Ko'Ou, Alfred, 2018, An annotated checklist of the chondrichthyans of Papua New Guinea, pp. 1-82 in Zootaxa 4411 (1) on page 45, DOI: 10.11646/zootaxa.4411.1, http://zenodo.org/record/1221878
Drosophila freilejoni Hunter 1979
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Drosophila
Drosophila freilejoni

description: freilejoni Hunter, 1979: 373. Type locality: Colombia, near Bogotá. HT M (CAS). NT Distr.: Colombia (Bogota, D.C). Refs.: Hunter, 1992: 197.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 726, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Informing interventions to reduce tobacco use among homeless women
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Poverty is a strong predictor of smoking, with the highest rates observed among the poorest individuals. While people from low-income communities attempt to quit at rates comparable to the general population, they succeed at rates far lower. In addition, while quit rates among women are lower than men, and while stress is associated with continued use in women, few interventions are specifically designed for women, let alone unstably housed women who experience extreme chronic stress. This study will test the influence of factors uniquely common in homeless women on smoking and elucidate the social context of smoking cessation. Our goal is to develop tobacco treatment recommendations specific to homeless and unstably housed women.
Pristis clavata Garman 1906
Creators: name: White, William T.
name: Ko'Ou, Alfred
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Chondrichthyes
Pristiformes
Pristidae
Pristis
Pristis clavata

description: Pristis clavata Garman, 1906
Dwarf Sawfish
Pristis clavata Garman, 1906: 208. Holotype: MCZ 733 -S. Type locality: Queensland, Australia.
Local synonymy: Dulvy et al., 2016: 142 (PNG); White et al., 2017a: 277 (PNG); White et al., 2018: 194, figs (PNG).
PNG voucher material: (1 spec.) KFRS E.428 (dried rostrum), rostrum length 178 mm, Daru, Western Province.
Remarks: An additional 8 specimens (6 registered lots) from the KFRS collection are considered lost or destroyed; all collected in the mid 1960’s. Dried fins observed from coastal fisheries during recent surveys in the Gulf and Western Provinces. White et al. (2017a) lists reports from unpublished survey reports from the 1970s; species identifications not verifiable.
description: Published as part of White, William T. & Ko'Ou, Alfred, 2018, An annotated checklist of the chondrichthyans of Papua New Guinea, pp. 1-82 in Zootaxa 4411 (1) on page 45, DOI: 10.11646/zootaxa.4411.1, http://zenodo.org/record/1221878
Structure of HIV-1 Rev oligomeric complexes on the RRE
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: All cells contain instructions in their genetic material that are required to perform various activities for sustenance and reproduction. These instructions exist in segments of the genetic material called genes. Cellular activities are controlled by a large number of molecules, mostly proteins, whose functions are dictated by their respective genes. In human cells (and most other cells), the genetic material (and consequently the genes) is located in a compartment called the nucleus. Instructions on genes are read by a set of proteins and messages (molecules called mRNA) are prepared in the nucleus. The mRNAs are then processed to a stage when they are ready to be read. Subsequently, they are sent into another compartment called the cytoplasm where they are read and proteins are made according to the instructions in them. If the mRNAs are not made correctly or processed completely, they are retained in the nucleus and are destroyed. When HIV attacks human cells, its genetic material gets integrated with the human genetic material. The virus makes the human proteins read its genetic material and prepare its mRNAs. However, in contrast to the human mRNAs, not all of the HIV mRNAs require processing. In fact, for HIV to survive, reproduce and infect more cells, some of its mRNAs should not be processed but sent out as such to the cytoplasm. Since human cells destroy mRNAs that do not get processed, they will also destroy unprocessed viral mRNAs. In order to send the unprocessed viral messages out to the cytoplasm, the virus has evolved a strategy by producing a protein called Rev. Multiple molecules of Rev load themselves onto a specific region of these unprocessed viral mRNAs called Rev-Response-Element (RRE). This big molecular complex then enables the transport of the unprocessed viral mRNAs into the cytoplasm without getting destroyed or processed. Since the transport of unprocessed viral mRNAs is an important step in viral reproduction in human cells, it is essential for us to know how this step is executed so that we can develop drugs to block it. Typically, in order to understand how a device/machine functions, we need to know how it looks, what its parts are and how they function. Similarly, it is necessary for us to understand what the Rev-RRE molecular complex looks like to come up with hypotheses of how it works to transport the viral mRNAs into the cytoplasm. My proposal aims at developing an understanding of the structure and architecture of the Rev-RRE complex by studying pieces of it at a time and then combining the information gained from each piece (akin to pieces in a jigsaw puzzle) to develop a model of the full complex.
Drosophila fulvimacula Patterson & Mainland 1944
Creators: name: Tidon, Rosana
name: Almeida, Jonathan Mendes De
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Drosophilidae
Drosophila
Drosophila fulvimacula

description: fulvimacula Patterson & Mainland, 1944, 42. Type locality: Mexico, Veracruz, Sedeno Canyon near Jalapa. HT M (USNM). NT Distr.: Mexico (Veracruz) to Brazil. Colombia (Cundinamarca (Fusagasugá), Meta (Villavicencio)). Refs.: Hunter & Navarro, 1969: 1102; Yoon, 1996: 35.
description: Published as part of Tidon, Rosana & Almeida, Jonathan Mendes De, 2016, FAMILY DROSOPHILIDAE, pp. 719-751 in Zootaxa 4122 (1) on page 726, DOI: 10.11646/zootaxa.4122.1.63, http://zenodo.org/record/263272
Development of a 3D Structural Model for the HIV-1 5'UTR RNA
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: A project is proposed to develop a working low-resolution model for the three-dimensional structure of 5-prime-untranslated region (5-prime-UTR) of the HIV-1 genomic RNA. 5-prime-UTR is a part of viral RNA that does not code for proteins, but is critical for many steps of the viral life cycle. This region is very strongly conserved among HIV-1 strains, and it is highly structured. Many structural elements and their functional roles have been characterized in 5-prime-UTR. However, our understanding of a spatial relationship between these elements is essentially one-dimensional or two-dimensional at best; it is based only on the proximity of secondary structure elements in the primary structure (sequence). A truly three-dimensional model of the 5-prime-UTR structure can advance our understanding of complex interactions taking place in this region, help refine existing and define new targets for anti-HIV therapeutic strategies. The project will be mostly computational in its nature; the miniCarlo software will be used to calculate the model. A specific hypothesis will be tested that the existing computational techniques can be used to successfully predict de novo the three-dimensional fold of the multi-domain 5-prime-UTR RNA of HIV-1. The success of the prediction will be judged on agreement with experimental structural information derived from the fluorescence resonant energy transfer (FRET) and small angle x-ray scattering (SAXS) data acquired for the 5-prime-UTR transcript in vitro. FRET experiments register exchange of energy between fluorescent probes attached to specific sites on 5-prime-UTR, which can be used to estimate the distances between these sites; experimental distances can be directly compared to the distances predicted by the model. SAXS data are sensitive to the overall shape of the molecule. The scattering curve can be calculated from the predicted model and compared with the experimental curve. If the hypothesis is proven incorrect, we will fall back on refining the model using FRET data as experimental restraints. A long-term goal is to refine this model based on acquired low-resolution structural data (SAXS and extended FRET measurements) and to extend the modeled system to study the dimerization of the 5-prime-UTR (including the primary and a possible alternative dimerization sites), mechanism of the dimer maturation, possible effects of downstream RNA sequences on the 5-prime-UTR structure, and effects of various proteins known to interact with 5-prime-UTR (starting with nucleocapsid protein, tat, and human cyclin T1).
Case study materials on Pinelands growth factors
Creators: name: Associates, Alan Mallach
Publisher: name: No Publisher Supplied
Year: 1980

description: This study presents the results of interviews and background study into current and anticipated development and. land use trends in five selected Pinelands municipalities:- Galloway Township in Atlantic County- Hammontown Township in Atlantic County- Manchester Township Ocean County- Tabernacle Township  in Burlington County- Waterford Township in Camden County
Land market trends in the Pinelands
Creators: name: Associates, Alan Mallach
Publisher: name: No Publisher Supplied
Year: 1980

description: This report represents a preliminary effort to identify the major features and trends in the land market affecting the Pinelands region. Through an analysis of trends and patterns during recent years, it is anticipated that it will be possible to identify different patterns of land activity in the Pinelands, in terms of time period and geographic subarea, and thereby anticipate potential future development pressures and directions affecting the region.