cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Artificial Intelligence for Radiographers – a systematic review
Creators: name: Bol, Karin
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Professional issues
subject: Radiographers
subject: Neural networks
subject: Computer Applications-General
subject: Health policy and practice
subject: Technology assessment
subject: Education and training
subject: Quality assurance
subject: Workforce

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Artificial Intelligence (AI) has developed at high speed the last few years and will substantially change various disciplines (1,2). These changes are also noticeable in the field of radiology, nuclear medicine and radiotherapy. However, the focus...
(401429) John Scott
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Nitric oxide release: Part I. Macromolecular scaffolds
Creators: name: Riccio, Daniel A.
name: Schoenfisch, Mark H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The roles of nitric oxide (NO) in physiology and pathophysiology merit the use of NO as a therapeutic for certain biomedical applications. Unfortunately, limited NO payloads, too rapid NO release, and the lack of targeted NO delivery have hindered the clinical utility of NO gas and low molecular weight NO donor compounds. A wide-variety of NO-releasing macromolecular scaffolds has thus been developed to improve NO’s pharmacological potential. In this tutorial review, we provide an overview of the most promising NO release scaffolds including protein, organic, inorganic, and hybrid organic-inorganic systems. The NO release vehicles selected for discussion were chosen based on their enhanced NO storage, tunable NO release characteristics, and potential as therapeutics.
Nitric oxide release: Part II. Therapeutic applications
Creators: name: Schoenfisch, Mark H.
name: Carpenter, Alexis W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: A wide range of nitric oxide (NO)-releasing materials have emerged as potential therapeutics that exploit NO’s vast biological roles. Macromolecular NO-releasing scaffolds are particularly promising due to their ability to store and deliver larger NO payloads in a more controlled and effective manner compared to low molecular weight NO donors. While a variety of scaffolds (e.g., particles, dendrimers, and polymers/films) have been cleverly designed, the ultimate clinical utility of most NO-releasing macromolecules remains unrealized. Although not wholly predictive of clinical success, in vitro and in vivo investigations have enabled a preliminary evaluation of the therapeutic potential of such materials. Herein, we review the application of macromolecular NO therapies for cardiovascular disease, cancer, bacterial infections, and wound healing.
Interplay between spinal cord and cerebral cortex metabolism in amyotrophic lateral sclerosis
Creators: name: BELLINI, ALESSANDRO
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder, characterized by a degeneration of upper and lower motor neurons leading to a progressive muscular paralysis. Although median survival most often averages 3?4 years, the large variability of its course (Calvo et al., 2017) raises an urgent need to develop biomarkers able to characterize the mechanisms underlying disease progression and to improve the diagnostic yield of clinical and neuro-physiological evaluation. Most studies in this setting focused on cortical response to ALS. Among these approaches, brain PET studies with 18F-?uorodeoxyglucose (FDG) already reported a signi?cant reduction in glucose metabolism (Pagani et al., 2014) in motor and premotor cortex (Kiernan et al., 1994; Abrahams et al., 1996, 2005). By contrast, involvement of the spinal cord has been characterized in relatively lower detail, mostly because of the anatomical features of this structure that limit the standardization of its evaluation. Consequently, a large uncertainty still exists about the mechanisms underlying ALS-induced damage in the spinal cord and its relationship with cortical impairment. We recently reported the potential of the Hough transform in delineating spinal cord structure and metabolic activity in a population of ALS patients subjected to FDG PET/CT (Marini et al., 2016). Speci?cally, this classical pattern recognition approach for the automatic identi?cation of straight lines in the image has been recently extended to the recognition of more complex shapes. This computational 3D approach enabled the extraction of spinal cord metabolic information from whole body images and per- mitted us to document increased glucose consumption, possibly representing a potential and independent prognostic marker (Marini et al., 2016). In the present study, we simultaneously analysed brain and spinal cord FDG uptake in a series of prospectively recruited patients submitted to brain and wholebody PET/CT.
title: XIII. Speech acts: the Integrational account I – Der Sprechaktaspekt der Integrativen Sprachtheorie I
title: Linguistic research in progress (Part XIII, Summer Semester 1999)
titleType: Subtitle
Creators: name: (:Unkn) Unknown
Publisher: name: Freie Universität Berlin
Year: 2017
Subjects: subject: 400 Sprache::410 Linguistik

description: See the Editor's Summary introducing this Part.
title: Roles of Functional Magnetic Resonance Imaging (fMRI) in Pre-operative Low Grade Brain Tumour
Creators: name: Soo, Suet Woon
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Neuroradiology brain
subject: MR-Functional imaging
subject: Education
subject: Localisation
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: -To describe the use of functional MRI (fMRI) in surgery planning for patients with low-grade brain tumour. -Importance of fMRI in the clinical setting based on patient cases imaged in the MRI...
Valutazione e mitigazione dei rischi geo-idrologici derivanti da eventi catastrofici nell'area del Parco Nazionale delle Cinque Terre
Creators: name: RAIMONDI, LUCA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: This research is included in the field of studies for the evaluation and mitigation of geo-hydrological risks deriving from catastrophic rainfall events conducted in the Cinque Terre National Park area (Liguria) by the Department of Earth Sciences of the Environment and Life of University of Genoa (Italy). This activity made it possible to create and test a mathematical simulation model, in a physically based GIS environment, capable of carrying out 3D slope stability analysis (extended to a spatial domain) according to the pluviometric conditions assumed in the calculations. The experimentation first highlighted the limits of application of the "infinte slope" limit equilibrium method (LEM) used for the spatially 3D slope stability analysis in a GIS computerized geographical environment, also indicating improvement solutions for a more correct use. The input parameters of the soils (geotechnical, hydrogeological and geometric) entering the above mathematical expression were then examined. Their spatial distribution and their relationship with the local geo-morphometric-environmental control factors, on a basin and regional scale, were assessed, as well as their influence on the results was tested by comparing them with real phenomena and geomorphological processes observed in the chosen pilot area (i.e. Vernazza catchment affected on 25/10/2011 by a catastrophic rainfall event). All this experimentation led to the formulation of innovative calculation procedures and methods which were then coded in the Python programming language and developed in the open source QGIS application system in the form of executable "scripts". The predictive ability of the new model was tested in the aforementioned basin, comparing the spatial output data derived from the mathematical simulation with the real distribution of the surface landslides obtained from the analysis of aerial photos and site surveys. In summary, the system showed excellent potential for the preventive localization of soil mobilization phenomena on the slopes of a territorial domain where, in a neighborhood of 25 m away from the focal landslide areas, it was able to identify the 84% of the phenomena that actually occurred with a probability of 93% of the total of the aforementioned areas (with only 7% of false alarms).
Nitric oxide release: Part III. Measurement and reporting
Creators: name: Coneski, Peter N.
name: Schoenfisch, Mark H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Nitric oxide’s expansive physiological and regulatory roles have driven the development of therapies for human disease that would benefit from exogenous NO administration. Already a number of therapies utilizing gaseous NO or NO donors capable of storing and delivering NO have been proposed and designed to exploit NO’s influence on the cardiovascular system, cancer biology, the immune response, and wound healing. As described in Nitric Oxide Release Part I: Macromolecular Scaffolds and Part II: Therapeutic Applications, the preparation of new NO-release strategies/formulations and the study of their therapeutic utility are increasing rapidly. However, comparison of such studies remains difficult due to the diversity of scaffolds, NO measurement strategies, and reporting methods employed across disciplines. This tutorial review highlights useful analytical techniques for the detection and measurement of NO. We also stress the importance of reporting NO delivery characteristics to allow appropriate comparison of NO between studies as a function of material and intended application.
Additional file 1 of Seroprevalence of and risk factors for Q fever in dairy and slaughterhouse cattle of Jimma town, South Western Ethiopia
Creators: name: Deressa, Feyissa Begna
name: Kal, David Onafruo
name: Benti Deressa Gelalcha
name: Magalhães, Ricardo J. Soares
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Questionnaire/check list used during animal and risk factors data collection.
title: XIV. Speech acts, integrational II: sentence types and sentences – Der Sprechaktaspekt II: Satzarten und Sätze
title: Linguistic research in progress (Part XIV, Winter Semester 1999/2000)
titleType: Subtitle
Creators: name: (:Unkn) Unknown
Publisher: name: Freie Universität Berlin
Year: 2017
Subjects: subject: 400 Sprache::410 Linguistik

description: See the Editor's Summary introducing this Part.
Silica-based nanoprobes for biomedical imaging and theranostic applications
Creators: name: Vivero-Escoto, Juan L.
name: Huxford-Phillips, Rachel C.
name: Lin, Wenbin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Nanoparticle-based contrast agents are attracting a great deal of attention for various biomedical imaging and theranostic applications. Compared to conventional contrast agents, nanoparticles possess several potential advantages to improve in vivo detection and to enhance targeting efficiency. Silica-based nanoprobes can be engineered to achieve longer blood circulation times, specific clearance pathways, and multivalent binding. In this tutorial review, we summarize the latest progress on designing silica-based nanoprobes for imaging and theranostic applications. The synthesis of both solid silica and mesoporous silica nanoparticles is described, along with different approaches used for surface functionalization. Special emphasis is placed on the application of silica-based nanoprobes in optical, magnetic resonance, and multimodal imaging. The latest breakthroughs in the applications of silica nanoparticles as theranostic agents are also highlighted.
A decentralized framework for cross administrative domain data sharing
Creators: name: CAMERA, GIANCARLO
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Federation of messaging and storage platforms located in remote datacenters is an essential functionality to share data among geographically distributed platforms. When systems are administered by the same owner data replication reduces data access latency bringing data closer to applications and enables fault tolerance to face disaster recovery of an entire location. When storage platforms are administered by different owners data replication across different administrative domains is essential for enterprise application data integration. Contents and services managed by different software platforms need to be integrated to provide richer contents and services. Clients may need to share subsets of data in order to enable collaborative analysis and service integration. Platforms usually include proprietary federation functionalities and specific APIs to let external software and platforms access their internal data. These different techniques may not be applicable to all environments and networks due to security and technological restrictions. Moreover the federation of dispersed nodes under a decentralized administration scheme is still a research issue. This thesis is a contribution along this research direction as it introduces and describes a framework, called ?WideGroups?, directed towards the creation and the management of an automatic federation and integration of widely dispersed platform nodes. It is based on groups to exchange messages among distributed applications located in different remote datacenters. Groups are created and managed using client side programmatic configuration without touching servers. WideGroups enables the extension of the software platform services to nodes belonging to different administrative domains in a wide area network environment. It lets different nodes form ad-hoc overlay networks on-the-fly depending on message destinations located in distinct administrative domains. It supports multiple dynamic overlay networks based on message groups, dynamic discovery of nodes and automatic setup of overlay networks among nodes with no server-side configuration. I designed and implemented platform connectors to integrate the framework as the federation module of Message Oriented Middleware and Key Value Store platforms, which are among the most widespread paradigms supporting data sharing in distributed systems.
(401424) Joseph Benson Andrews
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Bronchial Artery Embolisation: Effective Pre-Procedure Planning Using CT Thoracic Aortogram
Creators: name: Soo, Suet Woon
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Interventional vascular
subject: Thorax
subject: CT-Angiography
subject: Embolisation
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: - A step by step approach to using CT aortogram for bronchial artery embolisation (BAE) planning. - Enable rapid identification of target lesion and target vessel to significantly reduce procedure time. - Identify low-yield lesions and vessels to...
title: Local recurrence of prostate cancer after radical radiotherapy on DCE and DWI MRI.
Creators: name: Rembak-Szynkiewicz, Justyna
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Genital / Reproductive system male
subject: Pelvis
subject: MR
subject: Diagnostic procedure
subject: Cancer
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Radical radiotherapy is one of the main treatment modalities of prostate cancer [1.2]. However, biochemical recurrence is reported in even 50% of patients with radical external radiotherapy (EBRT) [3]. Assessment of the prostate following radiation...
Absence of Perfect Conductance Quantization of Helical-edge Transport in Graphene under a Strong, Tilted Magnetic Field
Creators: name: Huang, Chunli
name: Cazalilla, Miguel. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In a recent experiment, Young et al. [Nature {\bf 505}, 528 (2014)] observed a metal to insulator transition as well as transport through helical edge states in monolayer graphene under a strong, tilted magnetic field. Under such conditions, the bulk is a magnetic insulator which can exhibit metallic conduction through helical edges. It was found that two-terminal conductance of the helical channels deviates from the expected quantized value at low-temperatures ($=e^2/h$ per edge, at zero temperature). Motivated by this observation, we study the effect of disorder on the conduction through the edge channels. We show that, unlike the situation in semiconducting quantum wells, a disorder Rashba spin-orbit coupling does not lead to backscattering, at least to leading order. Instead we find the lack of perfect anti-alignment of the electron spins in the helical channels to be the most likely source for backscattering arising from scalar (i.e. spin-independent) impurities. The intrinsic spin-orbit coupling and other time-reversal symmetry breaking and/or sublattice-parity breaking potentials also lead to (sub-leading) corrections to the channel conductance.
description: 12 pages and 6 pdf figures
title: Venous Blood Oxygen Change Detected by Quantitative Susceptibility Mapping in Parkinson's with Type 2 Diabetes Mellitus
Creators: name: li, wanyao
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Head and neck
subject: MR-Functional imaging
subject: Imaging sequences
subject: Developmental disease

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Purpose Thestudy used Quantitative Susceptibility Mapping (QSM) to quantitatively measurethe blood oxygen level of the cerebral vein in patients with Parkinson’s diseasewithType 2 Diabetes Melitus(PDDM) , and the correlation between each...
(401425) Mary Elizabeth Todd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(401426) Elsie M [Osborne]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Spotted: vulnerable plaque! A brief review of coronary atherosclerotic lesions on CT angiography
Creators: name: Constantin, Irina Lavinia
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Arteries / Aorta
subject: Cardiac
subject: Vascular
subject: CT-Angiography
subject: Contrast agent-intravenous
subject: Diagnostic procedure
subject: Arteriosclerosis
subject: Embolism / Thrombosis

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To recognize and compare different types of atherosclerotic lesions on computed tomography angiography (CTA). To assess the risk for future cardiac events according to each type of lesion. To decide on appropriate follow-up imaging techniques and/or...
Sustainable Building Construction for Quality Project Delivery in Nigeria
Creators: name: Solomon, S.S.
name: Usman, N.D.
name: Goro, S. A.
name: Sunday A.W.
Publisher: name: gjrpublication
Year: 2024

description: Sustainable construction is a rising concept that aims to incorporate the general principles of sustainability current practice of the construction industry but the reasons for the current unsustainable practice are not yet explored in Nigeria. This study “Sustainable Building Construction for quality Project Delivery” assessed level of awareness of benefit of Sustainable Construction practices and identified the current barriers to sustainable construction practices. This study is survey research that made use of structured questionnaires administered to purposively drawn sample from building construction stakeholders (clients, contractors and professionals/consultants). A total of 150 closed ended structured questionnaires were disseminated to the construction stakeholders in the construction industry based in Yola, Nigeria. 80 questionnaires were retrieved and analyzed using statistical package for social science (SPSS). The data generated from the survey were subjected to descriptive and quantitative analyses. It found that there was a significant difference in the awareness level of benefits of sustainable construction practices between building stakeholders. It has recommended that efforts should be made toward improving construction processes through sustainable construction practices awareness.
Perspectives on gravity-induced radiative processes in astrophysics
Creators: name: Papini, Giorgio
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Single-vertex Feynman diagrams represent the dominant contribution to physical processes, but are frequently forbidden kinematically. This is changed when the particles involved propagate in a gravitational background and acquire an effective mass. Procedures are introduced that allow the calculation of lowest order diagrams, their corresponding transition probabilities, emission powers and spectra to all orders in the metric deviation, for particles of any spin propagating in gravitational fields described by any metric. Physical properties of the "space-time medium" are also discussed. It is shown in particular that a small dissipation term in the particle wave equations can trigger a strong back-reaction that introduces resonances in the radiative process and affects the resulting gravitational background.
description: 8 pages, one figure. arXiv admin note: substantial text overlap with arXiv:1007.4834
Large-Area Plasmonics on Self-Organized Wrinkled Nanopatterns
Creators: name: BARELLI, MATTEO
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: The focus of my PhD project consisted in the development of self-organized, large area, industrially scalable physical methods based on wrinkling instabilities to nanopattern and functionalize tunable plasmonic polymeric polydimetilsyloxane (PDMS) and solid-state glass surfaces, both transparent, non-toxic and cheap materials, for applications of significant technological interest in photonics and bio-sensing.
Multisensory learning in adaptive interactive systems
Creators: name: VOLTA, ERICA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: The main purpose of my work is to investigate multisensory perceptual learning and sensory integration in the design and development of adaptive user interfaces for educational purposes. To this aim, starting from renewed understanding from neuroscience and cognitive science on multisensory perceptual learning and sensory integration, I developed a theoretical computational model for designing multimodal learning technologies that take into account these results. Main theoretical foundations of my research are multisensory perceptual learning theories and the research on sensory processing and integration, embodied cognition theories, computational models of non-verbal and emotion communication in full-body movement, and human-computer interaction models. Finally, a computational model was applied in two case studies, based on two EU ICT-H2020 Projects, "weDRAW" and "TELMI", on which I worked during the PhD.
Quantitative analysis of N-terminal valine peptide adducts specific for 1,2-epoxy-3-butene
Creators: name: Jayaraj, Karupiah
name: Gold, Avram
name: Upton, Patricia B.
name: Georgieva, Nadia I.
name: Boysen, Gunnar
name: Swenberg, James A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Butadiene (BD) metabolism shows gender, species and concentration dependency, making the extrapolation of animal results to humans complex. BD is metabolized mainly by cytochrome P450 2E1 to three epoxides, 1,2-epoxy-3-butene (EB), 1,2;3,4-diepoxybutane (DEB) and 1,2-epoxy-butanediol (EB-diol). For accurate risk assessment it is important to elucidate species differences in the internal formation of the individual epoxides in order to assign the relative risks associated with their different mutagenic potencies. Analysis of N-terminal globin adducts is a common approach for monitoring the internal formation of BD derived epoxides. Our long term strategy is to develop an LC–MS/MS method for simultaneous detection of all three BD hemoglobin adducts. This approach is modeled after the recently reported immunoaffinity LC–MS/MS method for the cyclic N,N-(2,3-dihydroxy-1,4-butadyil)-valine (pyr-Val, derived from DEB). We report herein the analysis of the EB-derived 2-hydroxyl-3-butenyl-valine peptide (HB-Val). The procedure utilizes trypsin hydrolysis of globin and immunoaffinity (IA) purification of alkylated heptapeptides. Quantitation is based on LC–MS/MS monitoring of the transition from the singly charged molecular ion of HB-Val (1–7) to the a1 fragment. Human HB-Val (1–11) was synthesized and used for antibody production. As internal standard, the labeled rat-[13C515N]-Val (1–11) was prepared through direct alkylation of the corresponding peptide with EB. Standards were characterized and quantified by LC–MS/MS and LC–UV. The method was validated with different amounts of human HB-Val standard. The recovery was >75% and coefficient of variation <25%. The LOQ was set to 100 fmol/injection. For a proof of principal experiment, globin samples from male and female rats exposed to 1000 ppm BD for 90 days were analyzed. The amounts of HB-Val present were 268.2 ± 56 and 350 ± 70 pmol/g (mean ± S.D.) for males and females, respectively. No HB-Val was detected in controls. These data are much lower compared to previously reported values measured by GC–MS/MS. The difference may be due higher specificity of the LC–MS/MS method to the N-terminal peptide from the α-chain versus derivatization of both α- and β-chain by Edman degradation, and possible instability of HB-Val adducts during long term storage (about 10 years) between the analyses. These differences will be resolved by examining recently collected samples, using the same internal standard for parallel analysis by GC–MS/MS and LC–MS/MS. Based on our experience with pyr-Val adduct assay we anticipate that this assay will be suitable for evaluation of HB-Val in multiple species.
title: Multi-modal Imaging-guided Pancreatic Cancer Photothermal Immunotherapy with Injectable BV-TP5 Hydrogel
Creators: name: Zhang, Wenjia
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Hybrid Imaging
subject: Oncology
subject: Pancreas
subject: MR
subject: Ablation procedures
subject: Laser
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Pancreatic cancer is one of the most devastating cancers globally and has the lowest 5-year survival rate of 10% [1], which compromises the performance of traditional therapeutic regimens in the clinic because of stromal resistance to systemic drug...
(401427) Cornelia O'Brian
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Human benzene metabolism following occupational and environmental exposures
Creators: name: Waidyanatha, Suramya
name: Lan, Qing
name: Rappaport, Stephen M.
name: Smith, Martyn T.
name: Zhang, Luoping
name: Vermeulen, Roel
name: Yin, Songnian
name: Li, Guilan
name: Kim, Sungkyoon
name: Rothman, Nathaniel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We previously reported evidence that humans metabolize benzene via two enzymes, including a hitherto unrecognized high-affinity enzyme that was responsible for an estimated 73 percent of total urinary metabolites [sum of phenol (PH), hydroquinone (HQ), catechol (CA), E,E-muconic acid (MA), and S-phenylmercapturic acid (SPMA)] in nonsmoking females exposed to benzene at sub-saturating (ppb) air concentrations. Here, we used the same Michaelis-Menten-like kinetic models to individually analyze urinary levels of PH, HQ, CA and MA from 263 nonsmoking Chinese women (179 benzene-exposed workers and 84 control workers) with estimated benzene air concentrations ranging from less than 0.001 ppm to 299 ppm. One model depicted benzene metabolism as a single enzymatic process (1-enzyme model) and the other as two enzymatic processes which competed for access to benzene (2-enzyme model). We evaluated model fits based upon the difference in values of Akaike’s Information Criterion (ΔAIC), and we gauged the weights of evidence favoring the two models based upon the associated Akaike weights and Evidence Ratios. For each metabolite, the 2-enzyme model provided a better fit than the 1-enzyme model with ΔAIC values decreasing in the order 9.511 for MA, 7.379 for PH, 1.417 for CA, and 0.193 for HQ. The corresponding weights of evidence favoring the 2-enzyme model (Evidence Ratios) were: 116.2:1 for MA, 40.0:1 for PH, 2.0:1 for CA and 1.1:1 for HQ. These results indicate that our earlier findings from models of total metabolites were driven largely by MA, representing the ring-opening pathway, and by PH, representing the ring-hydroxylation pathway. The predicted percentage of benzene metabolized by the putative high-affinity enzyme at an air concentration of 0.001 ppm was 88% based upon urinary MA and was 80% based upon urinary PH. As benzene concentrations increased, the respective percentages of benzene metabolized to MA and PH by the high-affinity enzyme decreased successively to 66% and 77% at 0.1 ppm, 20% and 58% at 1 ppm, and 2.7% and 17% at 10 ppm. This indicates that the putative high-affinity enzyme was active primarily below 1 ppm and favored the ring-opening pathway.
Additional file 1 of Systematic design of separation process for bioethanol production from corn stover
Creators: name: Amornraksa, Suksun
name: Ittipat Subsaipin
name: Simasatitkul, Lida
name: Suttichai Assabumrungrat
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Systematic design of separation process for bioethanol production from corn stover.
Predictive Whole-Body Control of Humanoid Robot Locomotion
Creators: name: DAFARRA, STEFANO
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Humanoid robots are machines built with an anthropomorphic shape. Despite decades of research into the subject, it is still challenging to tackle the robot locomotion problem from an algorithmic point of view. For example, these machines cannot achieve a constant forward body movement without exploiting contacts with the environment. The reactive forces resulting from the contacts are subject to strong limitations, complicating the design of control laws. As a consequence, the generation of humanoid motions requires to exploit fully the mathematical model of the robot in contact with the environment or to resort to approximations of it. This thesis investigates predictive and optimal control techniques for tackling humanoid robot motion tasks. They generate control input values from the system model and objectives, often transposed as cost function to minimize. In particular, this thesis tackles several aspects of the humanoid robot locomotion problem in a crescendo of complexity. First, we consider the single step push recovery problem. Namely, we aim at maintaining the upright posture with a single step after a strong external disturbance. Second, we generate and stabilize walking motions. In addition, we adopt predictive techniques to perform more dynamic motions, like large step-ups. The above-mentioned applications make use of different simplifications or assumptions to facilitate the tractability of the corresponding motion tasks. Moreover, they consider first the foot placements and only afterward how to maintain balance. We attempt to remove all these simplifications. We model the robot in contact with the environment explicitly, comparing different methods. In addition, we are able to obtain whole-body walking trajectories automatically by only specifying the desired motion velocity and a moving reference on the ground. We exploit the contacts with the walking surface to achieve these objectives while maintaining the robot balanced. Experiments are performed on real and simulated humanoid robots, like the Atlas and the iCub humanoid robots.
title: CT imaging features of cardiac masses: A pictorial review
Creators: name:  Vitkovskyi , Yurii
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: Cardiovascular system
subject: Oncology
subject: CT
subject: CT-Angiography
subject: Diagnostic procedure
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: The main goals is: 1. to demonstrate the diagnostic value of CT in the evaluation of cardiac masses 2. to show typical imaging features of cardiac tumors 3. to highlight the benefits of CT among other imaging...
Parents' perceptions about the values and benefits of electronic games on young children in Jordan: A case study
Creators: name: AL-Ghwairy, Halah
Publisher: name: University of Southern Queensland
Year: 2024
Subjects: Electronic games
parents' decision-making
religion
culture
parents' perceptions
young children

description: The popularity of electronic games among young children is increasing in both Western and Arab countries. The COVID-19 epidemic escalated the use of electronic games for both fun and educational purposes. For families with young children aged 18 months to 4.5 years, parents are recognised as gatekeepers for children’s use of electronic games; however, with this comes their conflicting perspectives on the values and benefits of electronic games. Much of the existing literature on the use of electronic games has focused on Western contexts, neglecting to explore the influence of culture on parental perceptions and subsequent decisions regarding electronic game use. This study explored this phenomenon within the specific context of Jordanian families, with the intent to better understand their perspectives on this phenomenon. Moreover, the study sought to reveal the extent to which Jordanian culture influenced their perspectives and decision-making towards children’s access to electronic games. The data consisted of semi-structured interviews, photo documentation and naturalistic contextual observations. These approaches were applied to a purposeful sample of parents with small children, with a total of 10 participant families (N = 12). Thematic analysis was employed for the process of analysing the data. Findings highlight a strong correlation between culture, religion, and the decision-making process of parents regarding children’s use of electronic games. However, several extraordinary factors, such as the COVID-19 pandemic and the developmental level and age of children, at times overrode other priority areas. This study contributes to the body of literature and research related to parental values and decision-making in young children’s use of electronic games by broadening key insights into this phenomenon to Jordanian contexts and young families.
Control Infrastructure for a Pulsed Ion Accelerator
Creators: name: Persaud, A.
name: Regis, M. J.
name: Stettler, M. W.
name: Vytla, V. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We report on updates to the accelerator controls for the Neutralized Drift Compression Experiment II, a pulsed induction-type accelerator for heavy ions. The control infrastructure is built around a LabVIEW interface combined with an Apache Cassandra backend for data archiving. Recent upgrades added the storing and retrieving of device settings into the database, as well as ZeroMQ as a message broker that replaces LabVIEW's shared variables. Converting to ZeroMQ also allows easy access via other programming languages, such as Python.
Lightning-induced voltages on power lines: advances in modelling, computational effort optimization and innovative tools for the protection of overhead distribution lines
Creators: name: MESTRINER, DANIELE
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: The continuous growth of MV overhead distribution systems requires a constant improvement in terms of security and power quality. One of the most critical event that can cause the fault of a distribution line is represented by the atmospheric discharges and, among them, the most dangerous one is no-doubt the lightning stroke. In the transmission and distribution systems, lightning transients can be caused by either direct or indirect strikes. Indirect strikes are much more frequent than direct strikes and can cause flashovers, especially when the line insulation level is low. The computation of the lightning induced-voltages (i.e. the one related to the indirect strikes, which represent the most critical issue in distribution systems) is a very complicated task for two main reasons: 1) the number of uncertain parameters is high: it involves a correct representation of the current that flows in the lightning channel as well as a correct representation of the soil conductivity where the power line is located. 2) The computational complexity of the calculations that allow evaluating the final overvoltage is high because in this case we are dealing with the computation of electromagnetic fields and with the effect of such fields on the power line. Concerning the protecting measures the most widely employed are the use of shield wires, surge arrester and the increase of the line insulation level. This thesis aims at improving the problem of the lightning-induced voltages in overhead distribution lines in terms of three main concepts: 1) innovation of the existing models, 2) optimization of the computational effort and 3) introduction of innovative tools for the protecting scheme. In this framework, the thesis proposes a new channel-bae current model (1) , an analytical technique for the electromagnetic fields computation (2) , a new scheme for the lightning-induced voltages computation (2), a new approach for reducing the computational effort of the lightning performance computation (2 and 3) and an innovative approach for the evaluation of the mitigation effect of shield wires on the lightning-induced voltages (3).
title: Comparison of EOS Micro-dose protocol with Xray standard dose protocol for chest Radiation dose measurement: preliminary data.
Creators: name: Ragucci, Pasquala Pasquy
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Radiographers
subject: Plain radiographic studies
subject: Dosimetry
subject: Dosimetric comparison

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Patients are frequently exposed to numerous radiographs, during diagnosis and treatment, whether conservative or surgical, and follow-up. Chest imaging is often performed in young patients where radiation dose is of special concern. Frequent...
1,3-Butadiene: Biomarkers and application to risk assessment
Creators: name: Boysen, Gunnar
name: Albertini, Richard J.
name: Walker, Vernon E.
name: Vacek, Pamela M.
name: Carro, Sujey
name: Nakamura, Jun
name: Georgieva, Nadia I.
name: Swenberg, James A.
name: Tretyakova, Natalia
name: Troutman, John M.
name: Goggin, Melissa
name: Bordeerat, Narisa K.
name: Sram, Radim J.
name: Upton, Patricia B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: 1,3-Butadiene (BD) is a known rodent and human carcinogen that is metabolized mainly by P450 2E1 to three epoxides, 1,2-epoxy-3-butene (EB), 1,2:3,4-diepoxybutane (DEB) and 1,2-epoxy-3,4-butanediol (EB-diol). The individual epoxides vary up to 200-fold in their mutagenic potency, with DEB being the most mutagenic metabolite. It is important to understand the internal formation of the individual epoxides to assign the relative risk for each metabolite and to understand the molecular mechanisms responsible for major species differences in carcinogenicity. We have conducted extensive exposure-biomarker studies on mice, rats and humans. Using low exposures that range from current occupational levels to human exposures from tobacco smoke has provided evidence that mice are very different from humans, with mice forming ~200 times more DEB than humans at exposures of 0.1–1.5 ppm BD. While no gender differences have been noted in mice and rats for globin adducts or N-7 guanine adducts, female rats and mice had 2–3-fold higher Hprt mutations and DNA-DNA cross-links, suggesting a gender difference in DNA repair. Numerous molecular epidemiology studies have evaluated globin adducts and Hprt mutations, SCEs and chromosomal abnormalities. None of the blinded studies have shown evidence of human genotoxicity at current occupational exposures and studies of globin adducts have shown similar or lower formation of adducts in females than males. If one calculates the EB dose-equivalents for the three species, mice clearly differ from rats and humans, being ~44 and 174 times greater than rats and humans, respectively. These data provide a scientific basis for improved risk assessment of BD.
Estimation of Output Channel Noise for Continuous Variable Quantum Key Distribution
Creators: name: Thearle, Oliver
name: Assad, Syed M.
name: Symul, Thomas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Estimation of channel parameters is important for extending the range and increasing the key rate of continuous variable quantum key distribution protocols. We propose a new estimator for the channel noise parameter based on the method of moments. The method of moments finds an estimator from the moments of the output distribution of the protocol. This estimator has the advantage of being able to use all of the states shared between Alice and Bob. Other estimators are limited to a smaller publicly revealed subset of the states. The proposed estimator has a lower variance for high loss channel than what has previously been proposed. We show that the method of moments estimator increases the key rate by up to an order of magnitude at the maximum transmission of the protocol.
description: 5 pages, 3 figures