cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
CONSERVAZIONE DI RAZZE AVICOLE: CARATTERIZZAZIONE E CAPACITA' DI ADATTAMENTO
Creators: name: COLOMBO, ELENA
Publisher: name: Universit� degli Studi di Milano
Year: 2012

description: The aim of the present thesis was to characterize local turkeys and chicken breeds from a morphological, reproductive and genetic point of view. Two chicken breeds, Mericanel della Brianza and Valdarnese, and four turkey breeds, Nero d?Italia, Brianzolo, Bronzato dei Colli Euganei and Narragansett, were considered.
Furthermore, the adaptation ability of commercial chickens was studied.
The results stress the importance of the different activities of characterization in a breed conservation plan to increase and preserve local biodiversity.
Additional file 1 of Disconnectome of the migraine brain: a “connectopathy” model
Creators: name: Silvestro, Marcello
name: Tessitore, Alessandro
name: Caiazzo, Giuseppina
name: Scotto di Clemente, Fabrizio
name: Trojsi, Francesca
name: Cirillo, Mario
name: Esposito, Fabrizio
name: Tedeschi, Gioacchino
name: Russo, Antonio
Publisher: name: figshare
Year: 2021
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Supplementary table 1. Statistically significant differences in local connectome measures (t-test) in patients with MwoA compared to HC (local efficiency, clustering coefficient and node strength local values are higher in patients with MwoA compared to HC, betweenness centrality values are lower in patients with MwoA compared to HC, eigenvector centrality values are higher in patients with MwoA compared to HC except for marked nodes*).
Changing seasonal temperature offers a window of opportunity for stricter climate policy
Creators: name: Pfeifer, Lena
name: Otto, Ilona M.
Publisher: name: Amsterdam [u.a.] : Elsevier Science
Year: 2022
Subjects: subject: Climate change concern
subject: Germany
subject: Longitudinal data
subject: Mitigation
subject: Observational weather data
subject: Seasonal temperature change
subject: 333.7
subject: 320

description: Environmental catastrophes, including the increased severity and frequency of climate extremes, can act as “windows of opportunities” that challenge citizens’ mental models and motivate them to engage in reflective processes, challenging their pre-conceived ideas. Less well understood is whether experiencing changing weather conditions, common in mid-latitudes, can have a similar effect and increase the citizens’ concerns about climate change and their willingness to accept more stringent climate policies. In this paper, we investigate the effects of changing seasonal temperature on the perceived seriousness of climate change and willingness to mitigate climate change. We use data from four yearly waves of a spatially explicit representative population survey in Germany and weather records from the postal code areas in which they live. To our knowledge, this study is the first analysis to link individual perceptions towards climate change and different mitigation options with seasonal temperature changes at specific locations in Europe. The analyzed perceptions were strongly influenced by socio-demographic characteristics and broader societal changes, as well as individual experiences of seasonal temperatures. The results show that experienced seasonal temperature change influences personal climate change concerns as well as the willingness to mitigate climate change, although with a weaker effect. The results indicate that it is the absolute temperature variation experienced that is important, rather than whether it is getting colder or warmer than usual. Considering the influences identified in this study can offer a window of opportunity for more stringent and targeted climate change policy.
Additional file 1 of Outcome of intracerebral cavernoma treated by Gamma Knife radiosurgery based on a double-blind assessment of treatment indication
Creators: name: Shen, Chiung-Chyi
name: Sun, Ming Hsi
name: Yang, Meng-Yin
name: You, Weir-Chiang
name: Sheu, Meei-Ling
name: Chen, Yen-Ju
name: Chen, Ying Ju
name: Sheehan, Jason
name: Pan, Hung-Chuan
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Figure S1: The treatment protocol was presented as a schematic flowchart. Figure S2: Cavernoma treated with nidus progression followed by second GKRS and craniotomy. A 29 year old female suffered facial numbness treated with GKRS and received a second GKRS due to increased volume of nidus with the recurrent symptom of facial numbness. The patient underwent a craniotomy due to intractable facial numbness and the surgery was associated with postoperative neurological deficits (a) MRI imaging of T2 at the time of GKRS with radiation volume of 2.4 cc with 12 Gy in 50% line (b) MRI imaging of T2 one year after GKRS with nidus volume of 0.5 cc (c) MRI imaging of T2 weighted 2 years after GKRS with nidus volume of 2.0 cc (d) MRI imaging of T2 at the time of second GKRS with radiation volume of 2.1 cc with 12 Gy in 50% line (e) MRI imaging of T2 9 years after a second GKRS and craniotomy with nidus volume of 1.1cc. Figure S3: Cavernoma treated with GKRS and demonstrating nidus progression and hemorrhage. A 41 year old female suffered facial numbness treated with GKRS and suffered the repeated bleedings (a) MRI imaging of T2, Flair and T1 with contrast at the time of gamma knife treatment with radiation volume of 0.1cc with 12 Gy in 50% line (b) MRI imaging of T2, Flair ,and T1 with contrast three year after GKRS with nidus volume of 0.21 cc (c) CT imaging 5 years after GKRS with intracerebral hemorrhage (d) MRI imaging of T2, Flair ,and T1 with contrast 5 years after GKRS with a nidus volume of 0.023 cc (e) MRI imaging of T2, FLAIR, and T1 with contrast 11 years after GKRS with a nidus volume of 0.021cc. Figure S4: Plot of life quality before and after GKRS. (a) Plot of life quality including SF-36 and KPS before and after GKRS. (b) Plot of life quality of SF-36 and KPS stratified by the etiologies of intracerebral hemorrhage and seizure. *: p<0.05; **:p<0.01. Figure S5: Plots of life quality of SF-36 and KPS in the patients either with or without development of new neurological deficits. **: p<0.01. Table S1: The associated factors contributing to the improvement of physical component. Table S2: The associated factors contributing to improvement in mental component. Table S3: The associated factors contributing to the improvement in KPS.
Improved search for muon-neutrino to electron-neutrino oscillations in MINOS
Creators: name: MINOS Collaboration
name: Adamson, P.
name: Auty, D. J.
name: Ayres, D. S.
name: Backhouse, C.
name: Barr, G.
name: Betancourt, M.
name: Bishai, M.
name: Blake, A.
name: Bock, G. J.
name: Boehnlein, D. J.
name: Bogert, D.
name: Cao, S. V.
name: Cavanaugh, S.
name: Cherdack, D.
name: Childress, S.
name: Coelho, J. A. B.
name: Corwin, L.
name: Cronin-Hennessy, D.
name: Danko, I. Z.
name: de Jong, J. K.
name: Devenish, N. E.
name: Diwan, M. V.
name: Dorman, M.
name: Escobar, C. O.
name: Evans, J. J.
name: Falk, E.
name: Feldman, G. J.
name: Frohne, M. V.
name: Gallagher, H. R.
name: Gomes, R. A.
name: Goodman, M. C.
name: Gouffon, P.
name: Graf, N.
name: Gran, R.
name: Grzelak, K.
name: Habig, A.
name: Hartnell, J.
name: Hatcher, R.
name: Himmel, A.
name: Holin, A.
name: Huang, X.
name: Hylen, J.
name: Irwin, G. M.
name: Isvan, Z.
name: Jaffe, D. E.
name: James, C.
name: Jensen, D.
name: Kafka, T.
name: Kasahara, S. M. S.
name: Koizumi, G.
name: Kopp, S.
name: Kordosky, M.
name: Kreymer, A.
name: Lang, K.
name: Lefeuvre, G.
name: Ling, J.
name: Litchfield, P. J.
name: Loiacono, L.
name: Lucas, P.
name: Mann, W. A.
name: Marshak, M. L.
name: Mathis, M.
name: Mayer, N.
name: McGowan, A. M.
name: Mehdiyev, R.
name: Meier, J. R.
name: Messier, M. D.
name: Michael, D. G.
name: Miller, W. H.
name: Mishra, S. R.
name: Mitchell, J.
name: Moore, C. D.
name: Mualem, L.
name: Mufson, S.
name: Musser, J.
name: Naples, D.
name: Nelson, J. K.
name: Newman, H. B.
name: Nichol, R. J.
name: Nowak, J. A.
name: Ochoa-Ricoux, J. P.
name: Oliver, W. P.
name: Orchanian, M.
name: Paley, J.
name: Patterson, R. B.
name: Pawloski, G.
name: Pearce, G. F.
name: Phan-Budd, S.
name: Plunkett, R. K.
name: Qiu, X.
name: Ratchford, J.
name: Rebel, B.
name: Rosenfeld, C.
name: Rubin, H. A.
name: Sanchez, M. C.
name: Schneps, J.
name: Schreckenberger, A.
name: Schreiner, P.
name: Shanahan, P.
name: Sharma, R.
name: Sousa, A.
name: Tagg, N.
name: Talaga, R. L.
name: Thomas, J.
name: Thomson, M. A.
name: Toner, R.
name: Torretta, D.
name: Tzanakos, G.
name: Urheim, J.
name: Vahle, P.
name: Viren, B.
name: Walding, J. J.
name: Weber, A.
name: Webb, R. C.
name: White, C.
name: Whitehead, L.
name: Wojcicki, S. G.
name: Yang, T.
name: Zwaska, R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We report the results of a search for $ν_{e}$ appearance in a $ν_μ$ beam in the MINOS long-baseline neutrino experiment. With an improved analysis and an increased exposure of $8.2\times10^{20}$ protons on the NuMI target at Fermilab, we find that $2\sin^2(θ_{23})\sin^2(2θ_{13})<0.12\ (0.20)$ at 90% confidence level for $δ\mathord{=}0$ and the normal (inverted) neutrino mass hierarchy, with a best fit of $2\sin^2(θ_{23})\sin^2(2θ_{13})\,\mathord{=}\,0.041^{+0.047}_{-0.031}\ (0.079^{+0.071}_{-0.053})$. The $θ_{13}\mathord{=}0$ hypothesis is disfavored by the MINOS data at the 89% confidence level.
description: 5 pages, 3 figures
NEXT-GENERATION SEQUENCING APPROACH FOR IDENTIFICATION OF CANDIDATE GENES IN ARRHYTHMOGENIC DISEASES
Creators: name: PIETRELLI, ALESSANDRO
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: Recent advances in genome sequencing technologies provided unexpected opportunities to characterize individual genomic landscape and identify mutations relevant for diagnosis and therapy in clinics. Specifically, whole-exome sequencing for complex disease (such as tumor/normal matched sample) and target resequencing for Mendelian disease, using next-generation sequencing (NGS) technologies, are gaining popularity in the human genetics community due to the moderate costs and the huge quantity of information provided by each experiment. However, NGS data analysis still remains the crucial bottleneck in this approach because of the great amount of data containing millions of potential disease-causing variants and difficulties involving the integration of different sources.
Here, we describe the application of a bioinformatics analysis pipeline for NGS data in two case studies about rare cardiac diseases. The case 1 is focused on the target sequencing of 158 candidate genes in 91 patients affected by Brugada Syndrome (BrS). To date the clinical phenotype is associated with mutations in the SCN5A gene but explain only the 30% of the BrS cases. Therefore we selected a panel of genes previously associated to cases of arrhythmogenic disorders in literature and we analysed them in a cohort of BrS patients, which were negative for known SCN5A mutations. We found 98 novel genetic variations and 60 clinical rs belonging to 70 genes. In particular we found 13 genes significantly mutated in our cohort compared to healthy controls in 1000 Genomes data that were not previously associated to BrS phenotype.
In case study 2 we performed a whole-exome sequencing experiment of trio family where the child is affected by a severe cardiac disease with unclear diagnosis. We developed a specific bioinformatics pipeline to filter out the germline mutations. We found six genes with novel deleterious mutations that were homozygous in the affected child, and heterozygous in both parents. Among the six mutated genes the TRDN and UNC45A genes were already associated to cardiac dysfunctions in literature. Functional studies will be performed to evaluate the involvement of the mutated genes in the disease onset.
In conclusion, we developed an automatic and versatile pipeline to analyse NGS data coming from whole-exome sequencing and target sequencing strategies. In addition, we integrated in the pipeline several public variation databases to evaluate and interpret the candidate mutations. The mutations found were validated by Sanger sequencing to evaluate the strength of the pipeline filters.
Additional file 1 of The COVID-19 pandemic: the effect on airway Management in non-COVID emergency patients
Creators: name: Ruangsomboon, Onlak
name: Boonmee, Phetsinee
name: Nimmannit, Akarin
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1 Table S1 Propensity score balance by standardized mean difference
Baltistena amplicollis Batelka & Rosová & Prokop 2023, comb. nov.
Creators: name: Batelka, Jan
name: Rosová, Kateřina
name: Prokop, Jakub
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Mordellidae
Baltistena
Baltistena amplicollis

description: Baltistena amplicollis (Ermisch, 1941) comb. nov.
(Figs 2D–G)
 Mordellistena amplicollis Ermisch, 1941a: 182. Holotype: Baltic amber.
 Type material examined. HOLOTYPE (SDEI): ‘ MORDELLISTENA [p] / amplicollis [hw] / det. Ermisch 194 [p] i [hw, sic; white label glued on a bigger white label] // TYPE [p; in black frame, red label glued on the bigger white label] // SDEI Müncheberg / SDEI-Amb-000640 [p; yellowish label]’.
 Comments on identification. As pro- and mesotarsomere IV are distinctly broader and shallowly emarginated, this species cannot be attributed to Mordellistena. To distinguish it from other Eocene Mordellistenini see the Key below. Because of the uncertain generic identity of this species, it is transferred here into Baltistena new collective group.
description: Published as part of Batelka, Jan, Rosová, Kateřina & Prokop, Jakub, 2023, Diversity and morphology of Eocene and Oligocene Mordellidae (Coleoptera), pp. 451-478 in Acta Entomologica Musei Nationalis Pragae 63 (2) on page 458, DOI: 10.37520/aemnp.2023.027, http://zenodo.org/record/10621277
Additional file 2 of Rational engineering of Saccharomyces cerevisiae towards improved tolerance to multiple inhibitors in lignocellulose fermentations
Creators: name: Brandt, Bianca A.
name: García-Aparicio, Maria D. P.
name: Görgens, Johann F.
name: van Zyl, Willem H.
Publisher: name: figshare
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics

description: Additional file 2: Growth and ethanol yields in round 1 and round 2 transformants. The % increment in growth and ethanol yield relative to parental strain for the 1st round transformants (Figure S1) and 2nd round transformants (Figure S2) in fermentations with 2% SC-X supplemented with 65% v/v sugarcane hydrolysate at 120 h.
Stable periodic density waves in dipolar Bose-Einstein condensates trapped in optical lattices
Creators: name: Maluckov, Aleksandra
name: Gligoric, Goran
name: Hadzievski, Ljupco
name: Malomed, Boris A.
name: Pfau, Tilman
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: Density-wave patterns in (quasi-) discrete media with local interactions are known to be unstable. We demonstrate that \emph{stable} double- and triple- period patterns (DPPs and TPPs), with respect to the period of the underlying lattice, exist in media with nonlocal nonlinearity. This is shown in detail for dipolar Bose-Einstein condensates (BECs), loaded into a deep one-dimensional (1D) optical lattice (OL), by means of analytical and numerical methods in the tight-binding limit. The patterns featuring multiple periodicities are generated by the modulational instability of the continuous-wave (CW) state, whose period is identical to that of the OL. The DPP and TPP emerge via phase transitions of the second and first kind, respectively. The emerging patterns may be stable provided that the dipole-dipole (DD) interactions are repulsive and sufficiently strong, in comparison with the local repulsive nonlinearity. Within the set of the considered states, the TPPs realize a minimum of the free energy. Accordingly, a vast stability region for the TPPs is found in the parameter space, while the DPP\ stability region is relatively narrow. The same mechanism may create stable density-wave patterns in other physical media featuring nonlocal interactions, such as arrayed optical waveguides with thermal nonlinearity.
description: 7 pages, 4 figures, Phys. Rev. Lett., in press
AMPLITUDE SPECTRUM AREA AS A PREDICTOR OF SUCCESSFUL DEFIBRILLATION: THRESHOLD VALUES ANALYSIS IN A LARGE DATABASE OF OUT-OF-HOSPITAL CARDIAC ARREST TREATED BY DC-SHOCK
Creators: name: FINZI, ANDREA ALFONSO
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: La scelta del momento di procedure alla defibrillazione (DF) di un paziente in fibrillazione ventricolare (FV) comporta l?interruzione del massaggio cardiaco e, in caso di inefficacia, il rischio di aggiungere un ulteriore danno miocardico. Perci� � assai importante individuare un indicatore affidabile della probabilit� di successo utilizzabile in tempo reale. In questo studio � stata valutata la capacit� della Amplitude Spectrum Area (AMSA) nel predire l?esito della defibrillazione in una vasta popolazione di pazienti con arresto cardiaco extraospedaliero.
Sono stati acquisiti gli elettrocardiogrammi (ECG) dalla memoria dei defibrillatori esterni utilizzati dagli operatori del 118 di 7 province lombarde nel periodo 2008-2009 in 8419 eventi di arresto cardiaco. Di essi sono stati analizzati i 1055 nei quali � stata effettuata una DF. L?AMSA � stato calcolato analizzando una finestra di 2 sec di ECG che terminava 0.5 sec prima della DF utilizzando una trasformata di Fourier per l?ampiezza e la frequenza. Il successo della DF � stato definito come la presenza di un ritmo stabile a frequenza di 40 bpm 60 sec dopo la DF. Sono stati individuati i valori soglia dell?AMSA per discriminare il risultato della DF, sono state calcolate sensibilit�, specificit�, predittivit� positiva e negativa ed � stata misurata l?area sotto la curva ROC.
Sono stati inclusi 2442 eventi di DF, fra cui 1055 prime DF e 1387 successive. Sono risultate efficaci rispettivamente il 26% di tutte le DF, il 27% delle prime e il 25.2% delle successive. L?AMSA � risultato significativamente maggiore prima delle DF efficaci rispetto a quello ottenuto prima delle DF inefficaci (13.8 vs 6.9 mV-Hz, 13.9 vs. 6.8 mV-Hz, e 13.7 vs. 7 mV-Hz rispettivamente per tutte le DF ,le prime e le successive). L?intersezione delle curve di sensibilit�, specifict� e predittivit� ha identificato un valore soglia di AMSA di 9.5 mV-Hz capace di predire il risultato della DF con un valore bilanciato dell?80% per tutte, le prime e le successive DF. Valori di AMSA > 27 mV-Hz hanno correttamente previsto un successo del 100%, mentre un valore di 8,5 mV-Hz ha previsto l?insuccesso con predittivit� negativa > 95% ed un valore di 4 mV-Hz indicava il 100% di probabilit� di insuccesso. L?area sotto la curva ROC � risultata 0.872, 0.869 e 0.875 rispettivamente per tutte le DF, le prime e le successive.
In questa vasta popolazione di pazienti con arresto cardiaco un algoritmo AMSA � stato capace di predire l?esito della DF con notevole accuratezza. Una soglia specifica di AMSA che identifichi le probabilit� di successo o insuccesso � ottenibile anche durante massaggio cardiaco. Pertanto la decisione di attuare la DF basata sull?AMSA pu� essere utile per migliorare l?esito della rianimazione cardiopolmonare.
Additional file 1 of Rational engineering of Saccharomyces cerevisiae towards improved tolerance to multiple inhibitors in lignocellulose fermentations
Creators: name: Brandt, Bianca A.
name: García-Aparicio, Maria D. P.
name: Görgens, Johann F.
name: van Zyl, Willem H.
Publisher: name: figshare
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics

description: Additional file 1: Gene target improvements to transformants in literature and in the current study. The gene products, functions and reported strain improvements attributed to overexpression of various gene targets or the deletion of the FPS1 gene as found in the literature (Table S1), the fermentation parameters and % inhibitor conversion of partial FPS1 deletion transformants in 2% SC-X media supplemented with 65% v/v sugarcane hydrolysate at 168 h (Table S2). The statistical analysis of partial FPS1 transformants using ANOVA and T-test, with p
Additional file 4 of Prehospital assessment and management of postpartum haemorrhage- healthcare personnel’s experiences and perspectives
Creators: name: Leonardsen, Ann-Chatrin Linqvist
name: Helgesen, Ann Karin
name: Ulvøy, Linn
name: Grøndahl, Vigdis Abrahamsen
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 4. Anonymized data.
Additional file 3 of Prehospital assessment and management of postpartum haemorrhage- healthcare personnel’s experiences and perspectives
Creators: name: Leonardsen, Ann-Chatrin Linqvist
name: Helgesen, Ann Karin
name: Ulvøy, Linn
name: Grøndahl, Vigdis Abrahamsen
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 3. The questionnaire developed as part of the study, assessing knowledge and self-assessed competence in PPH handling.
Force-extension relation of cross-linked anisotropic polymer networks
Creators: name: Benetatos, Panayotis
name: Ulrich, Stephan
name: Zippelius, Annette
Publisher: name: arXiv
Year: 2012
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Cross-linked polymer networks with orientational order constitute a wide class of soft materials and are relevant to biological systems (e.g., F-actin bundles). We analytically study the nonlinear force-extension relation of an array of parallel-aligned, strongly stretched semiflexible polymers with random cross-links. In the strong stretching limit, the effect of the cross-links is purely entropic, independent of the bending rigidity of the chains. Cross-links enhance the differential stretching stiffness of the bundle. For hard cross-links, the cross-link contribution to the force-extension relation scales inversely proportional to the force. Its dependence on the cross-link density, close to the gelation transition, is the same as that of the shear modulus. The qualitative behavior is captured by a toy model of two chains with a single cross-link in the middle.
description: 7 pages, 4 figures
Confronting 2D delayed-detonation models with light curves and spectra of Type Ia supernovae
Creators: name: Blondin, S.
name: Kasen, D.
name: Roepke, F. K.
name: Kirshner, R. P.
name: Mandel, K. S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We compare models for Type Ia supernova (SN Ia) light curves and spectra with an extensive set of observations. The models come from a recent survey of 44 two-dimensional delayed-detonation models computed by Kasen, Roepke & Woosley (2009), each viewed from multiple directions. The data include optical light curves of 251 SNe Ia and 2231 low-dispersion spectra from the Center for Astrophysics, plus data from the literature. The analysis uses standard techniques employed by observers, including MLCS2k2, SALT2, and SNooPy for light-curve analysis, and the Supernova Identification (SNID) code of Blondin & Tonry for spectroscopic comparisons to assess how well the models match the data. We show that the models that match observed spectra best lie systematically on the observed width-luminosity relation. Conversely, we reject six models with highly asymmetric ignition conditions and a large amount (>1 M_sun) of synthesized 56Ni that yield poor matches to observed SN Ia spectra. More subtle features of the comparison include the general difficulty of the models to match the U-band flux at early times, caused by a hot ionized ejecta that affect the subsequent redistribution of flux at longer wavelengths. We examine ways in which the asymptotic kinetic energy of the explosion affects both the predicted velocity and velocity gradient in the Si II and Ca II lines. Models with an asymmetric distribution of 56Ni are found to result in a larger variation of photometric and spectroscopic properties with viewing angle, regardless of the initial ignition setup. We discuss more generally whether highly anisotropic ignition conditions are ruled out by observations, and how detailed comparisons between models and observations involving both light curves and spectra can lead to a better understanding of SN Ia explosion mechanisms.
description: 24 pages, 22 figures; accepted for publication in MNRAS
Additional file 2 of Prehospital assessment and management of postpartum haemorrhage- healthcare personnel’s experiences and perspectives
Creators: name: Leonardsen, Ann-Chatrin Linqvist
name: Helgesen, Ann Karin
name: Ulvøy, Linn
name: Grøndahl, Vigdis Abrahamsen
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2. The postpartum haemorrhage self-efficacy (PPHSE) and -collective efficacy (PPHCE) items.
EXPRESSION OF SUBSTANCE P IN BRAINSTEMS OF VICTIMS OF SUDDEN UNEXPLAINED PERINATAL DEATH
Creators: name: MEHBOOB, RIFFAT MEHBOOB
Publisher: name: Universit� degli Studi di Milano
Year: 2011

description: Sudden perinatal death including SIDS is a rare but lethal syndrome and there is no symptom of this disorder until the fatal outcome has occurred. Epidemiological, genetic, molecular and pathological studies conducted so far give us some possible explanations about it but are inadequate to explain it completely. Brainstem etiology is a mostly accepted hypothesis to induce sudden perinatal death. We investigated the immunohistochemical expression of substance P (SP) in the brainstems of 56 subjects aged from 17 gestational weeks to 10 postnatal months, died of unknown (sudden unexplained perinatal deaths and SIDS) and known causes (controls). The goals of this study were to obtain basic information about the expression of the SP during the first phases of human nervous system development; to evaluate whether there are altered manifestations of this neuromodulator in victims of sudden death; to verify the correlation with maternal cigarette smoking and to see the evolutionary aspects of SP gene (TAC1) through computational analysis.
Immunohistochemistry demonstrated SP-immunoreactivity in correspondence of the caudal trigeminal nucleus area, with progressive increase in density of positive fibers of the corresponding tract from fetal life to first postnatal months. So, we first delineated the structure of the human trigeminal nucleus, so far little investigated, and provided essential data on its morphologic and functional development. Nevertheless, a negativity or low SP-positivity of the tract fibres was detectable in a wide subset of SIDS and, conversely, high SP-expression in a wide subset of sudden fetal deaths. Therefore we postulate, on the basis of these results, the functional importance of the SP in the early phases of central nervous system development and in the regulation of autonomic functions.
Besides, the observation of a significant correlation between sudden unexplained death, altered SP staining and maternal smoking, prompted us to suppose a close relation between smoking absorption in utero and decrease of the functional activity of the trigeminal nucleus, leading to sudden death during pregnancy and in the first months of life. Computational analysis suggests that SP encoding gene (TAC1) is a singleton, appeared in vertebrates and is more prone to induce neuropathologies along with its interactors, if mutated or functionally altered, as it is located mostly in brain.
Ein Kastenverschluß der mittleren römischen Zeit von Wetzendorf, Kr. Querfurt
Creators: name: Schulz, Walther
Publisher: name: Jahresschrift für mitteldeutsche Vorgeschichte
Year: 2020

description: Jahresschrift für mitteldeutsche Vorgeschichte, Bd. 15 (1927): Jahresschrift für die Vorgeschichte der sächsisch-thüringischen Länder
Additional file 1 of Prehospital assessment and management of postpartum haemorrhage- healthcare personnel’s experiences and perspectives
Creators: name: Leonardsen, Ann-Chatrin Linqvist
name: Helgesen, Ann Karin
name: Ulvøy, Linn
name: Grøndahl, Vigdis Abrahamsen
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. The STROBE (Strengthening the reporting of observational studies in epidemiology) checklist.
SYNTHESIS AND DEVELOPMENT OF NEW ANTIBACTERIAL AGENTS INHIBITORS OF FTSZ
Creators: name: CHIODINI, GIUSEPPE
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: Elements of the bacterial cytoskeleton represent potential targets for antimicrobial compounds. FtsZ (Filamentous temperature sensitive Z) is a bacterial ancestor of eukaryotic tubulin. It possess markedly different structures than its eukaryotic analogue, making possible to develop specific inhibitors for the bacterial protein. The 3-methoxybenzamide (3-MBA) has a weak antibacterial activity against B. subtilis, it can easily penetrate bacterial cell and bind FtsZ at high ligand efficiency. The fluorinated 3-MBA analogue 2,6-difluoro-3-nonyloxybenzamide (compound 1) showed a significant activity against B. subtilis and S. aureus. Starting from the compound 1 we designed and synthesized a new series of derivatives that replaced the amide function with bioisosteric groups and new compounds differently substituted at the 3 position of the 2,6-difluoro-3-hydroxybenzamide.
Chemical tagging of three distinct populations of red giants in the globular cluster NGC 6752
Creators: name: Carretta, Eugenio
name: Bragaglia, Angela
name: Gratton, Raffaele
name: Lucatello, Sara
name: D'Orazi, Valentina
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present aluminium, magnesium, and silicon abundances in the metal-poor globular cluster NGC 6752 for a sample of more than 130 red giants with homogeneous oxygen and sodium abundances. We find that [Al/Fe] shows a spread of about 1.4 dex among giants in NGC 6752 and is anticorrelated with [Mg/Fe] and [O/Fe] and correlated with [Na/Fe] and [Si/Fe]. These relations are not continuous in nature, but the distribution of stars is clearly clustered around three distinct Al values, low, intermediate, and high. These three groups nicely correspond to the three distinct sequences previously detected using Stromgren photometry along the red giant branch. These two independent findings strongly indicate the existence of three distinct stellar populations in NGC 6752. Comparing the abundances of O and Mg, we find that the population with intermediate chemical abundances cannot originate from material with the same composition of the most O- and Mg-poor population, diluted by material with that of the most O- and Mg-rich one. This calls for different polluters.
description: 8 pages, 2 tables, 3 figures; uses emulateapj; accepted for publication on Astrophysical Journal Letters
Das Schweizerische Kunstarchiv
Creators: name: Schmid, Michael
Publisher: name: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft
Year: 2019

description: Seit der Gründung im Jahr 1951 sammelt SIK-ISEA systematisch Dokumente zur Schweizer Kunst. Im September 2012 eröffnete SIK-ISEA das Schweizerische Kunstarchiv, um seine Bestände für die Zukunft zu sichern und kontinuierlich auszubauen. Zudem wurden neue Vermittlungsgefässe im Web und vor Ort geschaffen.
description: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft, 2013: Jahresbericht 2012 SIK-ISEA
Additional file 2 of Technologies for recovery and reuse of plant nutrients from human excreta and domestic wastewater: a protocol for a systematic map and living evidence platform
Creators: name: Macura, Biljana
name: Thomas, James
name: Metson, Geneviève S.
name: McConville, Jennifer R.
name: Johannesdottir, Solveig L.
name: Seddon, Dan
name: Harder, Robin
Publisher: name: figshare
Year: 2021
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 2: Stakeholder survey with summary of responses.
Dependence of the Spin Transfer Torque Switching Current Density on the Exchange Stiffness Constant
Creators: name: You, Chun-Yeol
Publisher: name: arXiv
Year: 2012
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate the dependence of the switching current density on the exchange stiffness constant in the spin transfer torque magnetic tunneling junction structure with micromagnetic simulations. Since the widely accepted analytic expression of the switching current density is based on the macro-spin model, there is no dependence of the exchange stiffness constant. When the switching is occurred, however, the spin configuration forms C-, S-type, or complicated domain structures. Since the spin configuration is determined by the shape anisotropy and the exchange stiffness constant, the switching current density is very sensitive on their variations. It implies that there are more rooms for the optimization of the switching current density with by controlling the exchange stiffness constant, which is determined by composition and the detail fabrication processes.
ROLE OF LIVER X RECEPTOR ACTIVATION ON DIABETIC PERIPHERAL NEUROPATHY
Creators: name: ABBIATI, FEDERICO
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: Diabetic peripheral neuropathy (DPN) is associate with damages and abnormalities in myelin sheath. Similar changes have been observed in the peripheral nerves of streptozotocin (STZ)-treated rats, a model of type 1 diabetes. It is well known that diabetes blunt levels of neuroprotective molecules such as neuroactive steroids and we observed that the pathology induces a different lipid pattern in myelin due to an altered balance between saturated and unsaturated fatty acids, reduces cholesterol levels in myelin sheath and modifies expression of several important genes involved in lipid metabolism such as sterol regulatory element binding protein 1c (SREBP-1c).
Liver X Receptor (LXR) is a ligand-activated nuclear receptor that controls cholesterol and lipid metabolism directly regulating the expression of several genes involved in these pathways. In fact LXR family regulates adrenal steroidogenesis via their ability to control cholesterol homeostasis. Here we show that also in sciatic nerve of rat both LRX? and ? isoforms are expressed and that these receptors are functional. We observed that activation of LXRs in rat, using a synthetic ligand, is able to increase most of the enzymes involved in steroidogenesis rising neurosteroids levels and triggering protective effect of the sciatic nerve against DPN ameliorating physiological and functional tests.
Beside the effect on steroidogenesis, LXR is able to induce many genes involved in fatty acid biosynthesis. In particular we demonstrated that, in diabetic settings, LXR activation increases SREBP-1c function, restores myelin lipid species, strongly alterated by pathology, and recovers P0 expression levels to normal. Again, these LXR-modulated improvements are associated with restored myelin structure in sciatic nerve and enhanced performance in functional tests such as thermal nociceptive threshold and nerve conduction velocity. Moreover these lesson learned from the protective effects of LXR activation on DPN prompted us to focus our research on the possible cross talk between neurosteroids and lipogenesis.
We investigate if neuroactive steroids, in particular DHP and 3?-diol, may exert their protective effects by modulating the myelin lipid profile. Here, we observed that DHP and 3?-diol act on the lipogenic gene expression profile in the sciatic nerve of diabetic rats, restoring alterations in myelin sheath with an amelioration of the diabetic phenotype.
Ultimately these results suggest that LXR activation may represent a new pharmacological avenue to exert neuroprotective effects on diabetic peripheral neuropathy.
Baltistena antiqua Batelka & Rosová & Prokop 2023, comb. nov.
Creators: name: Batelka, Jan
name: Rosová, Kateřina
name: Prokop, Jakub
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Mordellidae
Baltistena
Baltistena antiqua

description: Baltistena antiqua (Ermisch, 1941) comb. nov.
(Figs 3A–C)
 Mordellistena antiqua Ermisch, 1941a: 181. Holotype: Baltic amber.
 Type material examined. HOLOTYPE (GPIH): ‘ TYPE [p; in black frame, red label] // 36 [p; white label] // D 52 [hw] / Mordellinae [hw] / Mordellistena antiqua [hw] / Determinator: [p] Ermisch [hw] 19 [p] 4i [hw, sic] / coll. A. SCHEELE, Berlin-Lichterfelde [p; white label with black frame and lines, red dot] // MORDELLISTENA [p] / antiqua [hw] / det. Ermisch 194 [p] i [hw, sic; white label] // Mordellistina [sic] antiqua Ermisch 1941 / Baltischer Bernstein / Holotypus,, Typ.Kat.Nr.3890, Scheele Nr. 36 [p; red label] // Mordellistena antiqua / ERMISCH 1941 / Baltischer Bernstein / GPIH- Scheele -0036 / Holotyp TK-Nr.: 3890 A / Familie: Mordellidae / Gattung: Mordellistena / Syninkl.: Lepidoptera (Köcher) [p; white label]’.
 Comments on identification. At least mesotarsomere IV is deeply dilated and bilobed so this species cannot be attributed to Mordellistena. To distinguish it from other Eocene Mordellistenini see the Key below.
 Because of its uncertain generic identity this species is transferred here into Baltistena new collective group.
  Baltistena goeckei (Ermisch, 1941) comb. nov.  Mordellistena goeckei Ermisch, 1941a: 179. Holotype:J, Baltic amber.
 Comments on identification. According to the curator of the GPIH collection only an empty bag with label ‘broken’ was found and the type is considered lost. At the moment we cannot add any comment to this species. To distinguish this species tentatively from other Eocene Mordellistenini see the note after the key below.
 Because the generic identity of this species cannot be investigated and supported, it is transferred here into Baltistena new collective group.
description: Published as part of Batelka, Jan, Rosová, Kateřina & Prokop, Jakub, 2023, Diversity and morphology of Eocene and Oligocene Mordellidae (Coleoptera), pp. 451-478 in Acta Entomologica Musei Nationalis Pragae 63 (2) on pages 458-459, DOI: 10.37520/aemnp.2023.027, http://zenodo.org/record/10621277
The first determination of the viscosity parameter in the circumstellar disk of a Be Star
Creators: name: Carciofi, Alex C.
name: Bjorkman, Jon E.
name: Otero, Sebastián A.
name: Okazaki, Atsuo T.
name: Štefl, Stanislav
name: Rivinius, Thomas
name: Baade, Dietrich
name: Haubois, Xavier
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Be stars possess gaseous circumstellar decretion disks, which are well described using standard $α$-disk theory. The Be star 28 CMa recently underwent a long outburst followed by a long period of quiescence, during which the disk dissipated. Here we present the first time-dependent models of the dissipation of a viscous decretion disk. By modeling the rate of decline of the V-band excess, we determine that the viscosity parameter $α=1.0\pm0.2$, corresponding to a mass injection rate $\dot{M}=(3.5\pm 1.3) \times 10^{-8}\ M_\sun\,\mathrm{yr}^{-1}$. Such a large value of $α$ suggests that the origin of the turbulent viscosity is an instability in the disk whose growth is limited by shock dissipation. The mass injection rate is more than an order of magnitude larger than the wind mass loss rate inferred from UV observations, implying that the mass injection mechanism most likely is not the stellar wind, but some other mechanism.
description: 4 pages, 3 figures, accepted for publication in ApJ Letters
Vorstand, Ehrenmitglieder
Creators: name: Redaktion, Die
Publisher: name: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft
Year: 2019

description: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft, 2014: Jahresbericht 2013 SIK-ISEA
CLINICAL PATHOLOGICAL FEATURES OF CANINE HEMATOPOIETIC NEOPLASMS ASSESSED VIA FLOW CYTOMETRY
Creators: name: MARTINI, VALERIA
Publisher: name: Universit� degli Studi di Milano
Year: 2014

description: Flow cytometry (FC) is an advanced diagnostic technique widely used in human medicine to confirm, classify and stage hematopoietic neoplasms (HNs): it supplies an objective evaluation of the size and internal complexity of the cells and identifies the antigenic pattern expressed by each cell, which is specific for cellular lineage and maturative stage. FC is presently spreading also in veterinary medicine and is mostly used to confirm the diagnosis and determine the immunophenotype of canine HNs.
Aim of this study was to apply FC to the study of specific clinical pathological features of canine HNs. In particular, we focused on three points:
1) staging of diffuse large B-cell lymphoma. We validated a FC technique to assess peripheral blood and bone marrow infiltration by neoplastic cells and proved its prognostic value.
2) antigen aberrancies. We investigated the prognostic role of specific antigen aberrancies in canine lymphomas and found the dogs with CD4+CD8+ T-cell lymphomas had a poorer prognosis compared to other T-cell aberrant lymphomas. In addition, we highlighted an important diagnostic role for antigen aberrancies in canine small clear cell lymphoma.
3) CD44 expression. We proved that CD44, which has a role in the pathogenesis and dissemination of many human and canine neoplasms, is expressed at different degrees on neoplastic cells from different canine HNs, with acute leukemias showing the highest degree of expression.
Overall, our results suggest that FC can be a useful tool not only to confirm the diagnosis and assess the immunophenotype of canine HNs, but also to assess clinical pathological aspects and additional prognostic parameters specific for the neoplastic subtype identified.
First-Order Reorientation of the Flux-Line Lattice in CaAlSi
Creators: name: Biswas, P. K.
name: Lees, M. R.
name: Balakrishnan, G.
name: Liao, D. Q.
name: Keeble, D. S.
name: Gavilano, J. L.
name: Egetenmeyer, N.
name: Dewhurst, C. D.
name: Paul, D. McK.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The flux line lattice in CaAlSi has been studied by small angle neutron scattering. A well defined hexagonal flux line lattice is seen just above Hc1 in an applied field of only 54 Oe. A 30 degree reorientation of this vortex lattice has been observed in a very low field of 200 Oe. This reorientation transition appears to be of first-order and could be explained by non-local effects. The magnetic field dependence of the form factor is well described by a single penetration depth of 1496(1) angstroms and a single coherence length of 307(1) angstroms at 2 K. At 1.5 K the penetration depth anisotropy is 2.7(1) with the field applied perpendicular to the c axis and agrees with the coherence length anisotropy determined from critical field measurements.
description: 5 pages including 6 figures, to appear in Physical Review Letters
Mitgliederverzeichnis
Creators: name: Redaktion, Die
Publisher: name: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft
Year: 2019

description: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft, 2014: Jahresbericht 2013 SIK-ISEA
Coherent cross-talk and parametric driving of matter-wave vortices
Creators: name: Parker, N. G.
name: Allen, A. J.
name: Barenghi, C. F.
name: Proukakis, N. P.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We show that the interaction between vortices and sound waves in atomic Bose-Einstein condensates can be elucidated in a double-well trap: with one vortex in each well, the sound emitted by each precessing vortex can be driven into the opposing vortex (if of the same polarity). This cross-talk leads to a periodic exchange of energy between the vortices which is long-range and highly efficient. The increase in vortex energy (obtained by numerical simulations of the Gross-Pitaevskii equation) is significant and experimentally observable as a migration of the vortex to higher density over just a few precession periods. Similar effects can be controllably engineered by introducing a precessing localised obstacle into one well as an artificial generator of sound, thereby demonstrating the parametric driving of energy into a vortex.
description: 12 pages, 13 figures