cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Elliptic Stable Envelopes for Certain Non-Symplectic Varieties and Dynamical $R$-Matrices for Superspin Chains from the Bethe/Gauge Correspondence
Creators: name: Ishtiaque, Nafiz
name: Moosavian, Seyed Faroogh
name: Zhou, Yehao
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Algebraic Geometry (math.AG)
subject: Quantum Algebra (math.QA)
subject: Representation Theory (math.RT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We generalize Aganagic-Okounkov's theory of elliptic stable envelopes, and its physical realization in Dedushenko-Nekrasov's and Bullimore-Zhang's works, to certain varieties without holomorphic symplectic structure or polarization. These classes of varieties include, in particular, classical Higgs branches of 3d $\mathcal N=2$ quiver gauge theories. The Bethe/gauge correspondence relates such a gauge theory to an anisotropic/elliptic superspin chain, and the stable envelopes compute the $R$-matrix that solves the dynamical Yang-Baxter equation (dYBE) for this spin chain. As an illustrative example, we solve the dYBE for the elliptic $\mathfrak{sl}(1|1)$ spin chain with fundamental representations using the corresponding 3d $\mathcal N=2$ SQCD whose classical Higgs branch is the Lascoux resolution of a determinantal variety. Certain Janus partition functions of this theory on $I \times \mathbb E$ for an interval $I$ and an elliptic curve $\mathbb E$ compute the elliptic stable envelopes, and in turn the geometric elliptic $R$-matrix, of the anisotropic $\mathfrak{sl}(1|1)$ spin chain. Furthermore, we consider the 2d and 1d reductions of elliptic stable envelopes and the $R$-matrix. The reduction to 2d gives the K-theoretic stable envelopes and the trigonometric $R$-matrix, and a further reduction to 1d produces the cohomological stable envelopes and the rational $R$-matrix. The latter recovers Rimányi-Rozansky's results that appeared recently in the mathematical literature.
Incidence, risk factors, and dose-volume relationship of radiation-induced rib fracture after carbon ion radiotherapy for lung cancer
Creators: name: Abe, Takanori
name: Shirai, Katsuyuki
name: Jun-Ichi Saitoh
name: Ebara, Takeshi
name: Shimada, Hirofumi
name: Tashiro, Mutsumi
name: Okano, Naoko
name: Ohno, Tatsuya
name: Nakano, Takashi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology

description: Background: The purpose of this study was to assess the incidence, risk factors, and dose-volume relationship of radiation-induced rib fracture (RIRF) after carbon ion radiotherapy for lung cancer. Material and methods: Fifty-seven ribs of 18 patients with peripheral stage I non-small cell lung cancer treated with carbon ion radiotherapy were analyzed on rib fracture. The patients were treated at a total dose of 52.8 Gy [relative biologic effectiveness (RBE)] or 60.0 Gy (RBE) in 4 fractions and were followed at least six months. Patient characteristics and dosimetric parameters were analyzed for associations with RIRF. Results: Eighteen patients and 57 ribs were included in this study. The median length of follow-up was 36.5 months. RIRF was observed in seven (39%) of the 18 patients, and in 11 (19%) of 57 ribs. Only one patient developed symptomatic fracture. The distance from the ribs to the tumor site was significantly shorter in fractured ribs than in non-fractured ribs (1.4 ± 0.3 cm vs. 2.5 ± 0.3 cm). Receiver operating characteristic curve analysis showed that as a cut-off value for discriminating RIRF had the largest area under the curve (AUC =0.78). Comparison of the two-year cumulative incidence of RIRF among two groups as determined by cut-off values, yielded the following result: 53% vs. 4% [, ≥ 38.2 Gy (RBE) or less]. Results from the two groups were significantly different (p Conclusion: The crude incidence of RIRF after carbon ion radiotherapy was 39% but incidence of symptomatic fracture was low. The as cut-off values may be helpful for discriminating the risk of RIRF.
On the Novikov problem with a large number of quasiperiods and its generalizations
Creators: name: Maltsev, A. Ya.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mathematical Physics (math-ph)
subject: Dynamical Systems (math.DS)
subject: Geometric Topology (math.GT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: The paper considers the Novikov problem of describing the geometry of level lines of quasi-periodic functions on the plane. We consider here the most general case, when the number of quasi-periods of a function is not limited. The main subject of investigation is the arising of open level lines or closed level lines of arbitrarily large sizes, which play an important role in many dynamical systems related to the general Novikov problem. As can be shown also, the results obtained for quasiperiodic functions on the plane can be generalized to the multidimensional case. In this case, we are dealing with a generalized Novikov problem, namely, the problem of describing level surfaces of quasiperiodic functions in a space of arbitrary dimension. Like the Novikov problem on the plane, the generalized Novikov problem plays an important role in many systems containing quasiperiodic modulations.
description: 15 pages, 4 figures, latex
Incidence, risk factors, and dose-volume relationship of radiation-induced rib fracture after carbon ion radiotherapy for lung cancer
Creators: name: Abe, Takanori
name: Shirai, Katsuyuki
name: Jun-Ichi Saitoh
name: Ebara, Takeshi
name: Shimada, Hirofumi
name: Tashiro, Mutsumi
name: Okano, Naoko
name: Ohno, Tatsuya
name: Nakano, Takashi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology

description: Background: The purpose of this study was to assess the incidence, risk factors, and dose-volume relationship of radiation-induced rib fracture (RIRF) after carbon ion radiotherapy for lung cancer. Material and methods: Fifty-seven ribs of 18 patients with peripheral stage I non-small cell lung cancer treated with carbon ion radiotherapy were analyzed on rib fracture. The patients were treated at a total dose of 52.8 Gy [relative biologic effectiveness (RBE)] or 60.0 Gy (RBE) in 4 fractions and were followed at least six months. Patient characteristics and dosimetric parameters were analyzed for associations with RIRF. Results: Eighteen patients and 57 ribs were included in this study. The median length of follow-up was 36.5 months. RIRF was observed in seven (39%) of the 18 patients, and in 11 (19%) of 57 ribs. Only one patient developed symptomatic fracture. The distance from the ribs to the tumor site was significantly shorter in fractured ribs than in non-fractured ribs (1.4 ± 0.3 cm vs. 2.5 ± 0.3 cm). Receiver operating characteristic curve analysis showed that as a cut-off value for discriminating RIRF had the largest area under the curve (AUC =0.78). Comparison of the two-year cumulative incidence of RIRF among two groups as determined by cut-off values, yielded the following result: 53% vs. 4% [, ≥ 38.2 Gy (RBE) or less]. Results from the two groups were significantly different (p Conclusion: The crude incidence of RIRF after carbon ion radiotherapy was 39% but incidence of symptomatic fracture was low. The as cut-off values may be helpful for discriminating the risk of RIRF.
Derecho de la salud y de la seguridad laboral y derecho del trabajo general. Algunas breves consideraciones metodológicas
Creators: name: Pascucci, Paolo
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: Questo breve scritto si sofferma sulla “relazione” tra il diritto del lavoro generale e quella sua parte che può essere denominata diritto speciale della sicurezza sul lavoro. Senza rivendicare una vera e propria autonomia del diritto della sicurezza sul lavoro, lo scritto cerca di evidenziare il contributo che quest’ultimo può offrire al diritto del lavoro generale specialmente in una fase come questa in cui esso è sottoposto a continue sfide e tensioni. This short essay focuses on the “relationship” between general labor law and that part of it which can be called special occupational safety law. Without claiming a real autonomy of the occupational safety law, the paper tries to highlight the contribution that the latter can offer to general labor law especially in a phase like this in which it is subjected to continuous challenges and tensions
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
La dimensión constitucional de la seguridad y salud en el trabajo
Creators: name: Aparicio Tovar, Joaquín
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: Aunque se conviniese que en los arts. 40.2 CE y 43.1 CE no existe un derecho a la protección de la salud, sino un principio que expresa una función necesaria del proceso democrático, tenemos también que convenir que algún sentido ha de tener que el precepto utilice la palabra derecho en el art. 43.1 e imponga a los poderes públicos un deber de velar por la salud e higiene en el trabajo. Conviene insistir en que la elección de esas palabras (derecho y la imposición de un deber) no es algo neutro, pues implica, como primera providencia, que el mandato dirigido al legislador impone la obligación de dar luz a derechos subjetivos. Es decir, no cualquier modo de proteger la salud y seguridad vale, sino que han de protegerse mediante la atribución de derechos subjetivos a favor de aquellos a quienes se quiere proteger. Even if it were agreed that in the arts. 40.2 EC and 43.1 EC there is no right to health protection, but a principle that expresses a necessary role of the democratic process, we must also agree that some sense must have the precept use the word right in Article 43.1 and impose on the public authorities a duty to ensure health and hygiene at work. It should be stressed that the choice of such words (right and the imposition of a duty) is not neutral, since it implies, as a first providence, that the mandate addressed to the legislature imposes an obligation to give light to subjective rights. That is, not every way to protect health and safety is worth it, but they must be protected by the attribution of subjective rights to those who are to be protected.
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Erratum to The SLUGGS Survey: The globular cluster systems of three early-type galaxies using wide-field imaging [Monthly Notices of the Royal Astronomical Society, 437, (2014) 273-292]
Creators: name: Kartha, Sreeja S.
name: Forbes, Duncan
name: Spitler, Lee R.
name: Romanowsky, Aaron J.
name: Arnold, Jacob A.
name: Brodie, Jean
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: The paper 'The SLUGGS survey: the globular cluster systems of three early-type galaxies using wide-field imaging' was published in Monthly Notices of the Royal Astronomical Society, 437, 273-292 (2014). In generating the Table 7 of this publication, we unintentionally wrote incorrect values for the total number of globular clusters (N GC) for NGC 720, NGC 1023, NGC 2768 and NGC 4278. Here, we give the correct values of N GC for NGC 720, NGC 1023 and NGC 2768 as 1489±96, 548±59 and 744±68, respectively. Note here that the values were given correctly in main text (Sections 3.7 and 5). We also update the N GC value for NGC 4278, published in Usher et al. (2013), as 1378±113. Additionally, the ratio of blue to red GCs (N BGC/N RGC) for NGC 720 and NGC 2768 given in Table 7 are also incorrect. The correct values for NGC 720 and NGC 2768 are 1.78 and 1.86, respectively. Similarly, the correct value for the ratio of blue to red GCs in NGC 4278 is 2.03. The new positions of NGC 720, NGC 2768 and NGC 4278 in fig. 21 of Kartha et al. (2014) are shifted slightly, but the results remain the same. The updated values for N BGC/N RGC are given here in Fig. 1. The conclusions of our paper remain unchanged.
L’individuazione del datore di lavoro per la sicurezza e i suoi riflessi sul piano sistematico
Creators: name: Lazzari, Chiara
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: Il saggio intende offrire una riflessione sul contributo che il “microsistema della sicurezza sul lavoro” può fornire al “sistema giuslavoristico” più generale, a partire dall’individuazione della figura del datore di lavoro e delle responsabilità che ad essa competono, anche utilizzando, quale terreno di verifica del possibile ricorso al principio funzionalistico – che con tanta evidenza emerge dalla normativa italiana in materia ai fini dell’attribuzione della qualifica datoriale – quello rappresentato dal lavoro tramite piattaforme digitali. The essay aims to provide with a reflection on the role played by the “occupational health and safety’s microsystem” in the more general “labour law system”, starting from the identification of the employer and his liabilities. To this end, the author addresses the topic represented by the digital labour platforms as a testbed for the possible application of the “functional principle” clearly envisaged by the Italian health and safety regulation to identify the employer
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Resonance Raman and vibrational mode analysis used to predict ligand geometry for docking simulations of a water soluble porphyrin and tubulin
Creators: name: McMicken, Brady
name: Parker, James E.
name: Thomas, Robert J.
name: Brancaleon, Lorenzo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: The ability to modify the conformation of a protein by controlled partial unfolding may have practical applications such as inhibiting its function or providing non-native photosensitive properties. A water-soluble porphyrin, meso-tetrakis (p-sulfonatophenyl) porphyrin (TSPP), non-covalently bound to tubulin can be used as a photosensitizer, which upon irradiation can lead to conformational changes of the protein. To fully understand the mechanism responsible for this partial unfolding and determine the amino acid residues and atoms involved, it is essential to find the most likely binding location and the configuration of the ligand and protein. Techniques typically used to analyze atomic position details, such as nuclear magnetic resonance and X-ray crystallography, require large concentrations, which are incompatible with the dilute conditions required in experiments for photoinduced mechanisms. Instead, we develop an atomistic description of the TSPP–tubulin complex using vibrational mode analysis from density functional theory calculations correlated to resonance Raman spectra of the porphyrin paired with docking simulations. Changes in the Raman peaks of the porphyrin molecule correlate with changes in its structural vibrational modes when bound to tubulin. The data allow us to construct the relative geometry of the porphyrin when bound to protein, which are then used with docking simulations to find the most likely configuration of the TSPP–tubulin complex.
Apuntes para la reconstrucción de un derecho del trabajo insolente y sensible. A propósito del concepto de trabajador subordinado
Creators: name: Trillo Párraga, Francisco
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: La crisis sistémica a la que asistimos desde el año 2008 ha impulsado la necesidad de indagar sobre la configuración de una sociedad que se dice fundamentada en las relaciones de producción capitalista. Esto es, en la consideración de que la sociedad se conforma por individuos que se insertan en grupos en función de la posición que ocupan en el sistema de producción capitalista. Posiciones que, como se sabe, autorizan una desigualdad social desde el momento en que la relación de trabajo por cuenta ajena aparece caracterizada por la subordinación del trabajador al empresario. Esta subordinación jurídica, también económica y social, se configura políticamente como contrapartida necesaria del sistema por el cual el trabajador accede a una serie de derechos individuales y colectivos que le otorgan el status de ciudadano. The systemic crisis we have witnessed since 2008 has driven the need to investigate the configuration of a society that is said to be based on capitalist production relations. That is, in the consideration of the company being composed of individuals who are inserted into groups depending on their position in the capitalist production system. Positions that, as we know, authorise social inequality from the moment when the employment relationship is characterized by the subordination of the worker to the employer. This legal subordination, also economic and social, is politically configured as a necessary counterpart to the system by which the worker accesses a series of individual and collective rights that grant him the status of citizen.
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Search for the exclusive $W$ boson hadronic decays $W^{\pm}\toπ^{\pm}γ$, $W^{\pm}\to K^{\pm}γ$ and $W^{\pm}\toρ^{\pm}γ$ with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for the exclusive hadronic decays $W^{\pm}\to π^{\pm}γ$, $W^{\pm}\to K^{\pm}γ$ and $W^{\pm}\to ρ^{\pm}γ$ is performed using up to $140\, \text{fb}^{-1}$ of proton-proton collisions recorded with the ATLAS detector at a center-of-mass energy of $\sqrt{s}=13\,\text{TeV}$. These rare processes provide a test bench for the quantum chromodynamics factorization formalism used to calculate cross sections at colliders, as well as a probe of $W$ boson coupling to quarks and a new way to measure the $W$ boson mass through fully reconstructed decay products. The search results in the most stringent upper limit to date on the branching fractions $\mathcal{B}(W^{\pm}\to π^{\pm}γ) < 1.9\times10^{-6}$, $\mathcal{B}(W^{\pm}\to K^{\pm}γ) < 1.7\times10^{-6}$, $\mathcal{B}(W^{\pm}\to ρ^{\pm}γ) < 5.2\times10^{-6}$ at 95% confidence level.
description: 36 pages in total, author list starting page 19, 2 figures, 2 tables, published in Phys. Rev. Lett. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2019-20
Diffusion coefficients preserving long-time correlations: Consequences on the Einstein relation and on entanglement in a bosonic Bogoliubov system
Creators: name: Hamdouni, Yamen
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We analytically derive the diffusion coefficients that drive a system of $N$ coupled harmonic oscillators to an equilibrium state exhibiting persistent correlations. It is shown that the main effect of the latter consists in a renormalization of the natural frequencies and the friction coefficients of the oscillators. We find that the Einstein relation may be satisfied at low temperatures with frequency-dependent effective friction coefficients, provided that the physical constraints are fulfilled. We also investigate the entanglement evolution in a bipartite bosonic Bogoliubov system initially prepared in a thermal squeezed state. It is found that, in contrast to what one may expect, strong coupling slows down the entanglement sudden death, and for initially separable states, entanglement generation may occur.
Synthesis, crystal structure, redox behavior and DNA-binding properties of a series of copper(II) complexes with two new carboxamide derivatives
Creators: name: Biplab Mondal
name: Buddhadeb Sen
name: Abhishek Maji
name: Zangrando, Ennio
name: Pabitra Chattopadhyay
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Chemistry
Earth and Environmental Sciences
Physics
Biochemistry
Biophysics

description: Four mononuclear copper(II) complexes of two new carboxamide derivatives formulated as [Cu(L1)2](ClO4)2 (1a), [Cu(L1)2](NO3)2 (1b), [Cu(L2)2(H2O)2](ClO4)2 (2a), and [Cu(L2)2(H2O)](NO3)2 (2b) have been isolated in pure form from the reaction of L1 and L2 [where L1 = N-(furan-2-ylmethyl)-2-pyridinecarboxamide and L2 = N-(thiophen-2-ylmethyl)-2-pyridinecarboxamide] with copper(II) salts of perchlorate and nitrate. All the complexes were characterized by physicochemical and spectroscopic tools along with single-crystal X-ray diffraction studies. The structural analyses showed that 1 is monomeric of square planar geometry with copper(II) chelated by two L1 ligands. Complex 2 differs in coordination geometry, being octahedral and distorted square pyramidal. Two L2 ligands occupy the equatorial positions of the octahedral 2a and the basal sites of the pyramidal 2b, with water molecules that complete the coordination sphere in each case. Electrochemical studies using cyclic voltammetry showed a reversible redox behavior of the copper(II) in 1 and 2. The electronic spectroscopic behavior and the trend of one electron equivalent redox potential corresponding to a CuII/CuI couple have also been confirmed by density functional theory calculations. The spectroscopic and viscosity measurement study in tris–HCl buffer suggested an intercalative interaction of 1a and 2 with calf thymus DNA likely due to the stacking between the non-coordinated furan and thiophene chromophore with the base pairs of DNA.
Un seminario italo-spagnolo su: “Revisando el Derecho del Trabajo desde la óptica de la seguridad y salud laboral” (Rivisitando il Diritto del lavoro con l’ottica della salute e sicurezza sul lavoro). Presentazione: un abbraccio scientifico, e non solo, tra Italia e Spagna
Creators: name: Pascucci, Paolo
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: Presentazione seminario
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Evidence for an intermediate-age, metal-rich population of globular clusters in NGC 4365
Creators: name: Larsen, Søren S.
name: Brodie, Jean
name: Beasley, Michael A.
name: Forbes, Duncan
name: Kissler-Patig, Markus
name: Kuntschner, Harald
name: Puzia, Thomas H.
Publisher: name: Swinburne
Year: 2024

description: Abstract not available.
Infezione da coronavirus e tutela contro gli infortuni e le malattie professionali
Creators: name: La Peccerella, Luigi
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: L’articolo affronta la questione dell’indennizzabilità da parte dell’Inail delle conseguenze dell’infezione da coronavirus sia per quanto attiene all’inquadramento della fattispecie “infortunio-malattia, sia con riferimento all’ambito soggettivo delle categorie protette, anche con alcune osservazioni critiche sull’esclusione di alcuni lavoratori parasubordinati. The article deals with the issue of indemnification by Inail (Italian National Institute for insurance against injuries at work) of the consequences of coronavirus infection both as regards the classification of the “injury-illness” case, and with reference to the protected categories of workers, also with some critical observations on the exclusion of some of them (“parasubordinati”).
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation
Creators: name: Su, Ling-Yan
name: Li, Hao
name: Lv, Li
name: Feng, Yue-Mei
name: Li, Guo-Dong
name: Rongcan Luo
name: He-Jiang Zhou
name: Lei, Xiao-Guang
name: Ma, Liang
name: Li, Jia-Li
name: Xu, Lin
name: Hu, Xin-Tian
name: Yao, Yong-Gang
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Earth and Environmental Sciences
Neuroscience
Cell Biology
Biochemistry

description: Autophagy is involved in the pathogenesis of neurodegenerative diseases including Parkinson disease (PD). However, little is known about the regulation of autophagy in neurodegenerative process. In this study, we characterized aberrant activation of autophagy induced by neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) and demonstrated that melatonin has a protective effect on neurotoxicity. We found an excessive activation of autophagy in monkey brain tissues and C6 cells, induced by MPTP, which is mediated by CDK5 (cyclin-dependent kinase 5). MPTP treatment significantly reduced total dendritic length and dendritic complexity of cultured primary cortical neurons and melatonin could reverse this effect. Decreased TH (tyrosine hydroxylase)-positive cells and dendrites of dopaminergic neurons in the substantia nigra pars compacta (SNc) were observed in MPTP-treated monkeys and mice. Along with decreased TH protein level, we observed an upregulation of CDK5 and enhanced autophagic activity in the striatum of mice with MPTP injection. These changes could be salvaged by melatonin treatment or knockdown of CDK5. Importantly, melatonin or knockdown of CDK5 reduced MPTP-induced SNCA/α-synuclein aggregation in mice, which is widely thought to trigger the pathogenesis of PD. Finally, melatonin or knockdown of CDK5 counteracted the PD phenotype in mice induced by MPTP. Our findings uncover a potent role of CDK5-mediated autophagy in the pathogenesis of PD, and suggest that control of autophagic pathways may provide an important clue for exploring potential target for novel therapeutics of PD.
La definizione di lavoratore in materia di salute e sicurezza: dall’universalità della tutela ai nuovi bisogni di tutela
Creators: name: Delogu, Angelo
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: L’intervento prende in esame la definizione di lavoratore dettata in materia di salute sicurezza sul lavoro, analizzandone i vari risvolti sistematici. Se, da un lato, tale nozione appare in astratto idonea a fornire adeguata copertura a tutti i bisogni protettivi emergenti nell’attuale realtà socioeconomica. Dall’altro lato, essa si confronta con sensibili diversificazioni delle discipline concretamente applicabili ai singoli rapporti lavorativi, che restituiscono un quadro assai frammentato, nel quale permangono ampi spazi di sotto-protezione. The intervention examines the definition of worker dictated in the field of health and safety at work, analyzing the various systematic implications. If, on the one hand, this notion appears abstractly suitable to provide adequate coverage for all the protective needs emerging in the current socio-economic situation. On the other hand, it confronts sensitive diversifications of the disciplines concretely applicable to individual working relationships, which return a very fragmented picture, in which large areas of under-protection remain
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Promoción de la seguridad y salud en los lugares de trabajo. Medidas de participación e intervención colectiva
Creators: name: Merino Segovia, Amparo
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: Los cambios en el entorno económico, institucional y tecnológico de las empresas han dado paso a nuevas fórmulas y métodos de organización del trabajo, con impactos en la salud y seguridad laboral. Urge en este contexto repensar las estructuras de representación colectiva en los lugares de trabajo y fortalecer la negociación colectiva en todos los ámbitos relacionados con la acción preventiva, especialmente en sectores, actividades, colectivos y empresas de mayor riesgo. Racionalizar los tiempos y los ritmos de trabajo, ecologizar las empresas, vinculando la salud laboral con la protección del medio ambiente, garantizar la seguridad y salud de los trabajadores en territorios dominados por la plataformización digital y en espacios locativos donde concurren pluralidad de actividades empresariales, aconseja reforzar los derechos de información, consulta y negociación, y diseñar propuestas que permitan adecuar el modelo representativo vigente a las nuevas formas organizativas, muchas de ellas caracterizadas por la dispersión espacial, atomización por descentralización interna o externa y conectividad virtual. Changes in the economic, institutional and technological environment of companies have given way to new formulas and methods of work organization, with impacts on health and job safety. In this context, it is important to rethink the structures of collective representation in the workplace and strengthen collective bargaining in all areas related to preventive action, especially in sectors, activities, groups and high risk companies. Rationalize working times and pace of work, green companies, linking occupational health with environmental protection, guarantee the safety and health of workers in territories dominated by digital platforms and in locative spaces where a plurality of business activities concur, advises to reinforce the rights of information, consultation and negotiation, and to design proposals that make it possible to adapt the current representative model to new organizational forms, many of them characterized by spatial dispersion, atomization by internal or external decentralization and virtual connectivity
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Todd polynomials and Hirzebruch numbers
Creators: name: Buchstaber, Victor M.
name: Veselov, Alexander P.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 57R20

description: In 1956 Hirzebruch found an explicit formula for the denominators of the Todd polynomials, which was proved later in his joint work with Atiyah. We present a new formula for the Todd polynomials in terms of the ``forgotten symmetric functions", which follows from our previous work on complex cobordisms. In particular, this leads to a simpler proof of the Hirzebruch formula and provides new interpretations for the Hirzebruch numbers.
description: Slightly revised version, published in the Proceedings of the Steklov Institute of Mathematics, 2024, Vol. 325
Rappresentanza e partecipazione nel diritto della salute e sicurezza dei lavoratori in Italia
Creators: name: Angelini, Luciano
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: Il saggio ripercorre le principali tappe dell’evoluzione del modello di tutela collettiva della salute e sicurezza in Italia, concentrandosi in particolare sulla figura dei Rappresentanti dei lavoratori per la sicurezza e sulle criticità che nel tempo ne hanno condizionato l’azione, nonostante il consistente pacchetto di diritti e prerogative attribuito dalla legge e dalla contrattazione collettiva. Dopo il rafforzamento di ruolo e funzioni attuato con il d.lgs. n. 81/2008, che ha valorizzato la rappresentanza territoriale e istituito la nuova figura di rappresentante di sito produttivo, la recente firma da parte delle Confederazioni Sindacali e di Confindustria di tre importanti accordi sulla strategia da seguire per rendere più efficace la tutela collettiva della salute e sicurezza dei lavoratori, induce a sperare che potremo in futuro contare su una rappresentanza più motivata e competente e su una contrattazione aziendale attenta e molto meglio orientata. The essay recaps step by step the evolution of the health and safety protection system in Italy, by focusing in particular on the role of workers’ safety representative and on the critical issues that have been an impact on their action over time, despite the substantial core rights and prerogatives envisaged by the law and the collective agreements. At first, the role and the prerogatives of the workers’ safety representative were implemented by the d.lgs. n. 81/2008, which enhanced the representation at territorial level and established a representation at production site level, later the three important agreements recently signed by the Trade Union Confederations and Confindustria based on a common strategy to make health and safety protection more effective, let us expect a more motivated and skilled representation and better oriented collective agreements at company level.
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Effect of Divalent Metal Cations on Contaminant Removal by Bicarbonate-Form Anion Exchange Resin
Creators: name: Rokicki, Christopher A.
name: Treavor H. Boyer
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: Cell Biology
subject: Biochemistry

description: This work investigated the role of divalent metal cations (Mg2+, Ca2+, and Cd2+) and subsequent precipitation or complexation on decreased contaminant removal by bicarbonate-form anion exchange resin (AER-HCO3) relative to chloride-form AER (AER-Cl). The results showed that the removal of dissolved organic carbon and nitrate was lower for AER-HCO3 than AER-Cl, and contaminant removal by AER-HCO3 was affected by the presence of metal cation. For instance, magnesium and cadmium exhibited the greatest and least interference, respectively, with contaminant removal by AER-HCO3. The results suggested that precipitation was not the cause of decreased contaminant removal by AER-HCO3, and instead implied that complex formation between the contaminant and divalent metal was responsible for differences in removal by AER
Necessary and Sufficient Conditions for Data-driven Model Reference Control
Creators: name: Wang, Jiwei
name: Baldi, Simone
name: van Waarde, Henk J.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: The objective of model reference control is to design a controller that regulates the system's behavior so as to match a specified reference model. This paper investigates necessary and sufficient conditions for model reference control from a data-driven perspective, when only a set of data generated by the system is utilized to directly accomplish the matching. Noiseless and noisy data settings are both considered. Notably, all methods we propose build on the concept of data informativity and do not rely on persistently exciting data.
Ancora su coronavirus e sicurezza sul lavoro: novità e conferme nello ius superveniens del d.P.C.M. 22 marzo 2020 e soprattutto del d.l. n. 19/2020
Creators: name: Pascucci, Paolo
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: Richiamando i precedenti saggi in materia dello stesso autore, il saggio analizza le novità normative nella gestione dell’emergenza coronavirus introdotte dal decreto del Presidente del Consiglio dei Ministri del 22 marzo 2020 e soprattutto dal decreto legge del 25 marzo 2020, n. 19. Il saggio si sofferma in particolare sul nuovo sistema sanzionatorio introdotto dal decreto n. 19/2020 il quale conferma come il sistema di gestione dell’emergenza sia completamente riconducibile ad una logica di tutela della salute pubblica. Inoltre, il saggio si sofferma sulla distinzione tra il sistema di gestione dell’emergenza del coronavirus e il tradizionale sistema di prevenzione aziendale sottolineando come il primo risponda al principio di precauzione, mentre il secondo attenga al principio di prevenzione. Infine si svolgono alcune considerazioni sulle possibili prospettive future ove sia necessario convivere per qualche tempo con la presenza del virus. Referring to the previous essays by the same author, the essay analyzes the regulatory changes in the management of the coronavirus emergency introduced by the Prime Minister's decree of 22 March 2020 and, above all, by the decree law of 25 March 2020, n. 19. The essay focuses in particular on the new sanctioning system introduced by decree no. 19/2020 which confirms that the emergency management system is completely attributable to a logic of protection of public health. In addition, the essay focuses on the distinction between the coronavirus emergency management system and the traditional system of health and safety at work, emphasizing how the former responds to the precautionary principle, while the latter adheres to the prevention principle. Finally, some considerations are made on possible future perspectives if it would be necessary to live with the presence of the virus for some time
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Two-detector flavor sensitivity to ultra-high-energy cosmic neutrinos
Creators: name: Testagrossa, Federico
name: Fiorillo, Damiano F. G.
name: Bustamante, Mauricio
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Ultra-high-energy (UHE) cosmic neutrinos, with energies above 100 PeV, could be finally discovered in the near future. Measuring their flavor composition would reveal information about their production and propagation, but new techniques are needed for UHE neutrino telescopes to have the capabilities to do it. We address this by proposing a new way to measure the UHE neutrino flavor composition that does not rely on individual telescopes having flavor-identification capabilities. We manufacture flavor sensitivity from the joint detection by one telescope sensitive to all flavors -- the radio array of IceCube-Gen2 -- and one mostly sensitive to $ν_τ$ -- GRAND. From this limited flavor sensitivity, predominantly to $ν_τ$, and even under conservative choices of neutrino flux and detector size, we extract important insight. For astrophysics, we forecast meaningful constraints on the neutrino production mechanism; for fundamental physics, vastly improved constraints on Lorentz-invariance violation. These are the first measurement forecasts of the UHE $ν_τ$ content.
description: Version published in PRD
Using Lyman-$α$ transits to constrain models of atmospheric escape
Creators: name: Schreyer, Ethan
name: Owen, James. E.
name: Loyd, R. O. Parke
name: Murray-Clay, Ruth
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Lyman-$α$ transits provide an opportunity to test models of atmospheric escape directly. However, translating observations into constraints on the properties of the escaping atmosphere is challenging. The major reason for this is that the observable parts of the outflow often comes from material outside the planet's Hill sphere, where the interaction between the planetary outflow and circumstellar environment is important. As a result, 3D models are required to match observations. Whilst 3D hydrodynamic simulations are able to match observational features qualitatively, they are too computationally expensive to perform a statistical retrieval of properties of the outflow. Here, we develop a model that determines the trajectory, ionization state and 3D geometry of the outflow as a function of its properties and system parameters. We then couple this model to a ray tracing routine in order to produce synthetic transits. We demonstrate the validity of this approach, reproducing the trajectory of the outflows seen in 3D simulations. We illustrate the use of this model by performing a retrieval on the transit spectrum of GJ 436 b. Our model constrains the sound speed of the outflow $\gtrsim 10 \text{ km s}^{-1}$, indicating that we can rule out core-powered mass loss as the mechanism driving the outflow for this planet. The bound on planetary outflow velocity and mass loss rates are consistent with a photoevaporative wind.
A Geometric Approach to Inelastic Collapse
Creators: name: Zheng, Yufei
name: Karntikoon, Kritkorn
name: Chazelle, Bernard
Publisher: name: Journal of Computational Geometry
Year: 2022

description: We show in this note how to interpret logarithmic spiral tilings as one-dimensional particle systems undergoing inelastic collapse. By deforming the spirals appropriately, we can simulate collisions among particles with distinct or varying coefficients of restitution. Our geometric constructions provide a strikingly simple illustration of a widely studied phenomenon in the physics of dissipative gases: the collapse of inelastic particles.
description: Journal of Computational Geometry, Vol. 13 No. 1 (2022)
Per un (più) moderno diritto della salute e della sicurezza sul lavoro: primi spunti di riflessione a partire dall’emergenza da Covid-19
Creators: name: Lazzari, Chiara
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2020

description: A partire dalla considerazione dell’emergenza da Covid-19, il saggio, avvalendosi come chiave interpretativa del concetto, di origine scientifica, di “salute circolare”, propone una lettura del rapporto fra organizzazione e ambiente inteso in senso lato, che si traduce anche in una riflessione sulla relazione fra art. 2087 c.c. e obbligo di valutazione dei rischi e in alcune proposte emendative del d.lgs. n. 81/2008, in tema, in particolare, di medico competente e rischio biologico. In the light of the emergency from Covid-19, through an interpretative key of the concept, of scientific origin, of the so-called “circular health”, the essay addresses the relationship between the organization and the environment lato sensu. The analysis focuses also on the relationship between the art. 2087 of the Civil Code and the risk assessment obligation and on some amended proposals concerning the Legislative Decree 81/2008, in particular, the occupational physician and the biological risk.
description: Diritto della sicurezza sul lavoro, N. 1 (2020)
Antifungal and phytotoxic activity of essential oil from root of Senecio amplexicaulis Kunth. (Asteraceae) growing wild in high altitude-Himalayan region
Creators: name: Singh, Rajendra
name: Ahluwalia, Vivek
name: Singh, Pratap
name: Kumar, Naresh
name: Sati, Om Prakash
name: Nitin Sati
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Plant Biology

description: This work was aimed to evaluate the essential oil from root of medicinally important plant Senecio amplexicaulis for chemical composition, antifungal and phytotoxic activity. The chemical composition analysed by GC/GC–MS showed the presence of monoterpene hydrocarbons in high percentage with marker compounds as α-phellandrene (48.57%), o-cymene (16.80%) and β-ocimene (7.61%). The essential oil exhibited significant antifungal activity against five phytopathogenic fungi, Sclerotium rolfsii, Macrophomina phaseolina, Rhizoctonia solani, Pythium debaryanum and Fusarium oxysporum. The oil demonstrated remarkable phytotoxic activity in tested concentration and significant reduction in seed germination percentage of Phalaris minor and Triticum aestivum at higher concentrations. The roots essential oil showed high yield for one of its marker compound (α-phellandrene) which makes it important natural source of this compound.
Resonance Raman and Vibrational Mode Analysis Used to Predict Ligand Geometry for Docking Simulations of a Water Soluble Porphyrin and Tubulin
Creators: name: McMicken, Brady
name: Parker, James E.
name: Thomas, Robert J.
name: Brancaleon, Lorenzo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Chemistry
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physics
subject: Biochemistry
subject: Biophysics

description: The ability to modify the conformation of a protein by controlled partial unfolding may have practical applications such as inhibiting its function or provide non-native photosensitive properties. A water soluble porphyrin, meso-tetrakis (p-sulfonatophenyl) porphyrin (TSPP), non-covalently bound to tubulin can be used as a photosensitizer, which upon irradiation can lead to conformational changes of the protein. To fully understand the mechanism responsible for this partial unfolding and determine the amino acid residues and atoms involved, it is essential to find the most likely binding location and the configuration of the ligand and protein. Techniques typically used to analyze atomic position details, such as nuclear magnetic resonance and X-ray crystallography, require large concentrations, which are incompatible with the dilute conditions required in experiments for photoinduced mechanisms. Instead, we develop an atomistic description of the TSPP-tubulin complex using vibrational mode analysis from density functional theory calculations correlated to resonance Raman spectra of the porphyrin paired with docking simulations. Changes in the Raman peaks of the porphyrin molecule correlate with changes in its structural vibrational modes when bound to tubulin. The data allows us to construct the relative geometry of the porphyrin when bound to protein, which are then used with docking simulations to find the most likely configuration of the TSPP-tubulin complex.
Proper holomorphic embeddings with small limit sets
Creators: name: Forstneric, Franc
Publisher: name: arXiv
Year: 2023
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: Primary 32H02, Secondary 32E10, 32Q56

description: Let $X$ be a Stein manifold of dimension $n\ge 1$. Given a continuous positive increasing function $h$ on $\mathbb R_+=[0,\infty)$ with $\lim_{t\to\infty} h(t)=\infty$, we construct a proper holomorphic embedding $f=(z,w):X\hookrightarrow \mathbb C^{n+1}\times \mathbb C^n$ satisfying $|w(x)|
Glyptothorax sardashtensis Jokar, Kamangar, Ghaderi & Freyhof 2023
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Siluriformes
Sisoridae
Glyptothorax
Glyptothorax sardashtensis

description: 215. Glyptothorax sardashtensis Jokar, Kamangar, Ghaderi & Freyhof, 2023
Common name. Sardasht sucking catfish
Taxonomy. Original description: Glyptothorax sardashtensis Jokar, Kamangar, Ghaderi & Freyhof 2023:482, Figs. 5B, D, F, H, 6–12 [Lesser Zab at bridge east of Nalas, Sardasht County, West Azerbaijan Province, Iran, 36.2688, 45.5012; holotype: FCFUK 300].
Revisions. None.
Illustrations. Jokar et al. (2023: 482, figs. 5, 6, 12).
Distribution in Iran. —Distribution in River Basin: Tigris.—Distribution in Ecoregions: 442-Upper Tigris & Euphrates.
Status in Iran. [Endemic].—Gorbemahi-e Sardasht.—Recorded from Iran in the original description by Jokar et al. (2023).—Iran material: FCFUK.
Conservation. —IUCN: NE.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 68, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097