cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Einsatz von Chatbots in der Kundenkommunikation
Creators: name: Radchenkova, Tatiana
name: Engelen, Monika
Year: 2023
Subjects: subject: 330 Wirtschaft

description: Die Welt der digitalen Kundenkommunikation entwickelt sich schnell. Die Kund:innen erwarten Rund-um-die-Uhr Unterstützung und eine schnelle Bearbeitung der Anfragen. Um dies zu ermöglichen, wer-den oft Chatbots in die Kundenkommunikation integriert. Das Ziel in der vorliegenden Arbeit ist es zu beantworten, welche Auswirkungen der Einsatz von Chat-bots auf die Kundenzufriedenheit und folglich Kundenloyalität und die Kundenwiederkaufrate haben kann. Um die Forschungsfrage zu beantworten, wurde eine Literaturrecherche und Sekundärdatenanalyse aktueller Bücher, wissenschaftlicher Arbeiten, Studien und Forschungen durchgeführt. Die qualitative Analyse der Ergebnisse der Literaturrecherche und Sekundärdatenanalyse zeigte, dass der Einsatz von Chatbots eine positive Auswirkung auf die Loyalität und das Wiederkaufpotenzial von Kund:innen haben kann und das Kundenerlebnis dadurch verbessert werden kann. Das vorliegende Praxis Paper fasst Erkenntnisse zum sinnvollen Einsatz von Chatbots zur Steigerung der Kundenzufriedenheit zusammen und leitet Handlungsempfehlungen ab. Diese Ausarbeitung basiert auf der Bachelorarbeit von Frau Tatiana Radchenkova, welche von März 2023 bis Juli 2023 von Frau Prof. Dr. Monika Engelen betreut wurde.
description: IBAL Schriftenreihe: Contributions to Business Administration and Leadership; 2023, 4
title: Le università per le città e i territori. Proposte per l’integrazione tra politiche universitarie e politiche urbane
Creators: name: Annese, Mariella
name: Mangialardi, Giovanna
name: Martinelli, Nicola
Publisher: name: Dipartimento di Architettura dell’Università di Bologna
Year: 2023

description: Il volume raccoglie i contributi proposti in occasione del Convegno Nazionale “Le Università per le città e i territori. Proposte per l’integrazione tra politiche universitarie e politiche urbane”, tenutosi presso il Dipartimento ArCoD del Politecnico di Bari, nelle date del 1 e 2 Dicembre 2022. Nelle due giornate di studio, il Convegno Nazionale ha avuto come principale obiettivo la riflessione condivisa sul tema del Diritto allo Studio, attraverso la costruzione di progettualità, politiche e interventi partecipati, finalizzati a rinsaldare il rapporto tra l’università e la città. I contributi in chiave multidisciplinare condividono riflessioni teoriche e sperimentazioni innovative sulla possibilità di integrazione tra politiche universitarie e urbane, dando spazio a molteplici attività che negli ultimi anni sono state promosse dalle Università italiane con impatti significativi su città e territori, da un punto di vista economico, sociale e culturale. Le molteplici sfaccettature del tema del Diritto allo studio sono state affrontate declinando le seguenti tematiche: Le attrezzature universitarie e del diritto allo studio come strumento di rigenerazione urbana; Il ruolo delle politiche culturali urbane e delle politiche giovanili; Le Agende di Sostenibilità Universitaria Urbana; Innovazione dell’offerta di servizi per il Diritto allo Studio; Inclusività e accessibilità delle strutture universitarie e degli spazi urbani
Does Education Affect Economic Growth? A Re-Examination of Empirical Data from China
Creators: name: Zhang, Yu
name: Liu, Jianguo
Publisher: name: MDPI
Year: 2022

description: From the perspective of the spatial differences of China’s educational development, exploring the impact of education on economic development is of great importance for alleviating the main contradiction between China’s inter provincial education and economic development. By collecting the spatial panel data from 31 provinces in China between 2011 and 2020, the study adopted spatial autocorrelation analysis and spatial Dubin model and conducted an empirical exploring the impact between China’s education development and economic growth. The findings of the paper include the following: (1) From the perspective of spatial correlation of the education development level, the improvement of education in China’s provinces affects and promotes each other nationwide; the spatial correlation of the improvement of education level presents a situation of strong combination. In provinces with a higher education level, education resources are relatively concentrated. (2) From the perspective of the role of education in promoting the economy, the improvement of education has a significant impact in promoting China’s economic growth, but it is not significant in the western region of China. Based on the research results, efforts should be made to improve the level of spatial correlation among provinces and cities. This study further suggests that, in the future, vigorously developing industries and vocational education in the western region should be considered as an important measure for China in promoting the coordinated development of the inter provincial economy in the future.
Distortive Effects of Initial-Based Name Disambiguation on Measurements of Large-Scale Coauthorship Networks
Creators: name: Kim, Jinseok
name: Diesner, Jana
Publisher: name: arXiv
Year: 2015
Subjects: subject: Digital Libraries (cs.DL)
subject: Social and Information Networks (cs.SI)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Scholars have often relied on name initials to resolve name ambiguities in large-scale coauthorship network research. This approach bears the risk of incorrectly merging or splitting author identities. The use of initial-based disambiguation has been justified by the assumption that such errors would not affect research findings too much. This paper tests this assumption by analyzing coauthorship networks from five academic fields - biology, computer science, nanoscience, neuroscience, and physics - and an interdisciplinary journal, PNAS. Name instances in datasets of this study were disambiguated based on heuristics gained from previous algorithmic disambiguation solutions. We use disambiguated data as a proxy of ground-truth to test the performance of three types of initial-based disambiguation. Our results show that initial-based disambiguation can misrepresent statistical properties of coauthorship networks: it deflates the number of unique authors, number of component, average shortest paths, clustering coefficient, and assortativity, while it inflates average productivity, density, average coauthor number per author, and largest component size. Also, on average, more than half of top 10 productive or collaborative authors drop off the lists. Asian names were found to account for the majority of misidentification by initial-based disambiguation due to their common surname and given name initials.
description: This is a preprint of an article accepted for publication in Journal of the Association for Information Science and Technology
Additional file 1 of Immune system modulation & virus transmission during parasitism identified by multi-species transcriptomics of a declining insect biocontrol system
Creators: name: Inwood, Sarah N.
name: Harrop, Thomas W. R.
name: Shields, Morgan W.
name: Goldson, Stephen L.
name: Dearden, Peter K.
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 1
Effects of Marine Protected Areas on Overfished Fishing Stocks with Multiple Stable States
Creators: name: Takashina, Nao
name: Mougi, Akihiko
Publisher: name: arXiv
Year: 2015
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: Marine protected areas (MPAs) have attracted much attention as a tool for sustainable fisheries management, restoring depleted fisheries stocks and maintaining ecosystems. However, even with total exclusion of fishing effort, depleted stocks sometimes show little or no recovery over a long time period. Here, using a mathematical model, we show that multiple stable states may hold the key to understanding the tendency for fisheries stocks to recover because of MPAs. We find that MPAs can have either a positive effect or almost no effect on the recovery of depleted fishing stocks, depending on the fish migration patterns and the fishing policies. MPAs also reinforce ecological resilience, particularly for migratory species. In contrast to previous reports, our results show that MPAs have small or sometimes negative effects on the recovery of sedentary species. Unsuitable MPA planning might result in low effectiveness or even deterioration of the existing condition.
description: 18 pages, 8 figures
Historic and future increase in the global land area affected by monthly heat extremes
Creators: name: Coumou, Dim
name: Robinson, Alexander
Publisher: name: Bristol : IOP Publishing
Year: 2013
Subjects: subject: Climate change
subject: climate modeling
subject: extreme event
subject: future prospect
subject: heterogeneity
subject: historical record
subject: seasonality
subject: spatiotemporal analysis
subject: twenty first century
subject: warming
subject: 500

description: Climatic warming of about 0.5 ° C in the global mean since the 1970s has strongly increased the occurrence-probability of heat extremes on monthly to seasonal time scales. For the 21st century, climate models predict more substantial warming. Here we show that the multi-model mean of the CMIP5 (Coupled Model Intercomparison Project) climate models accurately reproduces the evolution over time and spatial patterns of the historically observed increase in monthly heat extremes. For the near-term (i.e., by 2040), the models predict a robust, several-fold increase in the frequency of such heat extremes, irrespective of the emission scenario. However, mitigation can strongly reduce the number of heat extremes by the second half of the 21st century. Unmitigated climate change causes most (>50%) continental regions to move to a new climatic regime with the coldest summer months by the end of the century substantially hotter than the hottest experienced today. We show that the land fraction experiencing extreme heat as a function of global mean temperature follows a simple cumulative distribution function, which depends only on natural variability and the level of spatial heterogeneity in the warming.
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs.
Creators: name: Cunha, Dulce Lima
name: Sarkar, Hajrah
name: Eintracht, Jonathan
name: Harding, Philippa
name: Zhou, Jo Huiqing
name: Moosajee, Mariya
Publisher: name: The Francis Crick Institute
Year: 2023
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Model organisms
subject: Gene Expression
subject: Genetics & Genomics
subject: Developmental Biology
subject: Human Biology & Physiology
subject: Stem Cells

description: Congenital aniridia is a rare, pan-ocular disease causing severe sight loss, with only symptomatic intervention offered to patients. Approximately 40% of aniridia patients present with heterozygous nonsense variants in PAX6, resulting in haploinsufficiency. Translational readthrough-inducing drugs (TRIDs) have the ability to weaken the recognition of in-frame premature termination codons (PTCs), permitting full-length protein to be translated. We established induced pluripotent stem cell (iPSC)-derived 3D optic cups and 2D limbal epithelial stem cell (LESC) models from two aniridia patients with prevalent PAX6 nonsense mutations. Both in vitro models show reduced PAX6 protein levels, mimicking the disease. The repurposed TRIDs amlexanox and 2,6-diaminopurine (DAP) and the positive control compounds ataluren and G418 were tested for their efficiency. Amlexanox was identified as the most promising TRID, increasing full-length PAX6 levels in both models and rescuing the disease phenotype through normalization of VSX2 and cell proliferation in the optic cups and reduction of ABCG2 protein and SOX10 expression in LESCs. This study highlights the significance of patient iPSC-derived cells as a new model system for aniridia and proposes amlexanox as a new putative treatment for nonsense-mediated aniridia.
A super-Eddington wind scenario for the progenitors of type Ia supernovae: binary population synthesis calculations
Creators: name: Wang, Bo
name: Ma, Xin
name: Liu, Dongdong
name: Liu, Zhengwei
name: Wu, Chengyuan
name: Zhang, Jujia
name: Han, Zhanwen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The super-Eddington wind scenario has been proposed as an alternative way for producing type Ia supernovae (SNe Ia). The super-Eddington wind can naturally prevent the carbon--oxygen white dwarfs (CO WDs) with high mass-accretion rates from becoming red-giant-like stars. Furthermore, it works in low-metallicity environments, which may explain SNe Ia observed at high redshifts. In this article, we systematically investigated the most prominent single-degenerate WD+MS channel based on the super-Eddington wind scenario. We combined the Eggleton stellar evolution code with a rapid binary population synthesis (BPS) approach to predict SN Ia birthrates for the WD+MS channel by adopting the super-Eddington wind scenario and detailed mass-accumulation efficiencies of H-shell flashes on the WDs. Our BPS calculations found that the estimated SN Ia birthrates for the WD+MS channel are ~0.009-0.315*10^{-3}{yr}^{-1} if we adopt the Eddington accretion rate as the critical accretion rate, which are much lower than that of the observations (<10% of the observed SN Ia birthrates). This indicates that the WD+MS channel only contributes a small proportion of all SNe Ia. The birthrates in this simulation are lower than previous studies, the main reason of which is that new mass-accumulation efficiencies of H-shell flashes are adopted. We also found that the critical mass-accretion rate has a significant influence on the birthrates of SNe Ia. Meanwhile, the results of our BPS calculations are sensitive to the values of the common-envelope ejection efficiency.
description: 14 pages, 9 figures, 1 table, accepted for publication in Astronomy and Astrophysics
The multifaceted nature of uncertainty in structure-property linkage with crystal plasticity finite element model
Creators: name: Tran, Anh
name: Robbe, Pieterjan
name: Wildey, Tim
name: Zapiain, David Montes de Oca
name: Lim, Hojun
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Applications (stat.AP)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Uncertainty quantification (UQ) plays a critical role in verifying and validating forward integrated computational materials engineering (ICME) models. Among numerous ICME models, the crystal plasticity finite element method (CPFEM) is a powerful tool that enables one to assess microstructure-sensitive behaviors and thus, bridge material structure to performance. Nevertheless, given its nature of constitutive model form and the randomness of microstructures, CPFEM is exposed to both aleatory uncertainty (microstructural variability), as well as epistemic uncertainty (parametric and model-form error). Therefore, the observations are often corrupted by the microstructure-induced uncertainty, as well as the ICME approximation and numerical errors. In this work, we highlight several ongoing research topics in UQ, optimization, and machine learning applications for CPFEM to efficiently solve forward and inverse problems.
Drosophila SUMM4 complex couples insulator function and DNA replication control
Creators: name: Emelyanov, Alexander V
name: Keogh, Michael-C
name: Nevil, Markus
name: Duronio, Robert J
name: Skoultchi, Arthur I
name: Sun, Lu
name: Andreyeva, Evgeniya N
name: Fyodorov, Dmitry V
name: Hill, Christina A
name: Vershilova, Elena
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Asynchronous replication of chromosome domains during S phase is essential for eukaryotic genome function, but the mechanisms establishing which domains replicate early versus late in different cell types remain incompletely understood. Intercalary heterochromatin domains replicate very late in both diploid chromosomes of dividing cells and in endoreplicating polytene chromosomes where they are also underrelicated. Drosophila SNF2-related factor SUUR imparts locus-specific underreplication of polytene chromosomes. SUUR negatively regulates DNA replication fork progression; however, its mechanism of action remains obscure. Here we developed a novel method termed MS-Enabled Rapid protein Complex Identification (MERCI) to isolate a stable stoichiometric native complex SUMM4 that comprises SUUR and a chromatin boundary protein Mod(Mdg4)-67.2. Mod(Mdg4) stimulates SUUR ATPase activity and is required for a normal spatiotemporal distribution of SUUR in vivo. SUUR and Mod(Mdg4)-67.2 together mediate the activities of gypsy insulator that prevent certain enhancer-promoter interactions and establish euchromatin-heterochromatin barriers in the genome. Furthermore, SuUR or mod(mdg4) mutations reverse underreplication of intercalary heterochromatin. Thus, SUMM4 can impart late replication of intercalary heterochromatin by attenuating the progression of replication forks through euchromatin/heterochromatin boundaries. Our findings implicate a SNF2 family ATP-dependent motor protein SUUR in the insulator function, reveal that DNA replication can be delayed by a chromatin barrier and uncover a critical role for architectural proteins in replication control. They suggest a mechanism for the establishment of late replication that does not depend on an asynchronous firing of late replication origins.
Towards a Non-equilibrium Bethe ansatz for the Kondo Model
Creators: name: Bettelheim, Eldad
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We give integral equations for the generating function of the cummulants of the work done in a quench for the Kondo model in the thermodynamic limit. Our approach is based on an extension of the thermodynamic Bethe ansatz to non-equilibrium situations. This extension is made possible by use of a large $N$ expansion of the overlap between Bethe states. In particular, we make use of the Slavnov determinant formula for such overlaps, passing to a function-space representation of the Slavnov matrix . We leave the analysis of the resulting integral equations to future work.
description: Typos corrected. Crucial references added
Biogeochemical potential of biomass pyrolysis systems for limiting global warming to 1.5 °C
Creators: name: Werner, C.
name: Schmidt, H.-P.
name: Gerten, D.
name: Lucht, W.
name: Kammann, C.
Publisher: name: Bristol : IOP Publishing
Year: 2018
Subjects: subject: Negative emission technologies
subject: biochar
subject: bio-oil
subject: mitigation
subject: 1.5 goal
subject: PyCCS
subject: geoengnieering
subject: 500

description: Negative emission (NE) technologies are recognized to play an increasingly relevant role in strategies limiting mean global warming to 1.5 °C as specified in the Paris Agreement. The potentially significant contribution of pyrogenic carbon capture and storage (PyCCS) is, however, highly underrepresented in the discussion. In this study, we conduct the first quantitative assessment of the global potential of PyCCS as a NE technology based on biomass plantations. Using a process-based biosphere model, we calculate the land use change required to reach specific climate mitigation goals while observing biodiversity protection guardrails. We consider NE targets of 100–300 GtC following socioeconomic pathways consistent with a mean global warming of 1.5 °C as well as the option of additional carbon balancing required in case of failure or delay of decarbonization measures. The technological opportunities of PyCCS are represented by three tracks accounting for the sequestration of different pyrolysis products: biochar (as soil amendment), bio-oil (pumped into geological storages) and permanent-pyrogas (capture and storage of CO2 from gas combustion). In addition, we analyse how the gain in land induced by biochar-mediated yield increases on tropical cropland may reduce the pressure on land. Our results show that meeting the 1.5 °C goal through mitigation strategies including large-scale NE with plantation-based PyCCS may require conversion of natural vegetation to biomass plantations in the order of 133–3280 Mha globally, depending on the applied technology and the NE demand. Advancing towards additional bio-oil sequestration reduces land demand considerably by potentially up to 60%, while the benefits from yield increases account for another 3%–38% reduction (equalling 82–362 Mha). However, when mitigation commitments are increased by high balancing claims, even the most advanced PyCCS technologies and biochar-mediated co-benefits cannot compensate for delayed action towards phasing-out fossil fuels.
The Passing of Eugene Peterson and F.F. Bosworth: A Look at Their Transition and 'Ultimate Triumph'
Creators: name: Barnes, Roscoe
Publisher: name: figshare
Year: 2018
Subjects: subject: 210304 Biography
subject: FOS: History and archaeology
subject: 220401 Christian Studies (incl. Biblical Studies and Church History)
subject: FOS: Philosophy, ethics and religion
subject: 220402 Comparative Religious Studies
subject: History
subject: 210399 Historical Studies not elsewhere classified
subject: 220405 Religion and Society
subject: Religious Studies

description: Copyright © 2018 by Roscoe Barnes III #FFBosworth #EugenePeterson In this blog post, the writer discusses the passing of Eugene Peterson and F.F. Bosworth and how they both had conversations with their deceased loved ones as they were dying. The author suggests there are remarkable similarities in their final moments. He also notes the experiences of Peterson and Bosworth are not uncommon in church history. For more information on F.F. Bosworth, follow the Bosworth Matters blog at: http://ffbosworth.strikingly.com. #ChristTheHealer #BosworthMatters #BosworthMention
Coupled nonpolar-polar metal-insulator transition in 1:1 SrCrO$_3$/SrTiO$_3$ superlattices: A first-principles study
Creators: name: Zhou, Yuanjun
name: Rabe, Karin M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Using first principles calculations, we determined the epitaxial-strain dependence of the ground state of the 1:1 SrCrO$_3$/SrTiO$_3$ superlattice. The superlattice layering leads to significant changes in the electronic states near the Fermi level, derived from Cr $t_{2g}$ orbitals. An insulating phase is found when the tensile strain is greater than 2.2\% relative to unstrained cubic SrTiO$_3$. The insulating character is shown to arise from Cr $t_{2g}$ orbital ordering, which is produced by an in-plane polar distortion that couples to the superlattice d-bands and is stabilized by epitaxial strain. This effect can be used to engineer the band structure near the Fermi level in transition metal oxide superlattices.
Ethical implications of economic compensation for voluntary medical male circumcision for HIV prevention and epidemic control
Creators: name: Stuart, Rennie
name: Köhler, Johannes
name: Samuelson, Julia
name: Singh, Jerome Amir
name: Reis, Andreas Alois
Publisher: name: Public Library of Science
Year: 2022

description: Despite tremendous efforts in fighting HIV over the last decades, the estimated annual number of new infections is still a staggering 1.5 million. There is evidence that voluntary medical male circumcision (VMMC) provides protection against men’s heterosexual acquisition of HIV-1 infection. Despite good progress, most countries implementing VMMC for HIV prevention programmes are challenged to reach VMMC coverage rates of 90%. Particularly for men older than 25 years, a low uptake has been reported. Consequently, there is a need to identify, study and implement interventions that could increase the uptake of VMMC. Loss of income and incurred transportation costs have been reported as major barriers to uptake of VMMC. In response, it has been suggested to use economic compensation in order to increase VMMC uptake. In this discussion paper, we present and review relevant arguments and concerns to inform decision-makers about the ethical implications of using economic compensation, and to provide a comprehensive basis for policy and project-related discussions and decisions.
Additional file 1 of Non-ribosomal peptide synthetase (NRPS)-encoding products and their biosynthetic logics in Fusarium
Creators: name: Huang, Ziwei
name: Zhu, Wangjie
name: Bai, Yifan
name: Bai, Xuelian
name: Zhang, Huawei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Additional file 1. Table S1. Detail information for NRPS-type secondary metabolites in Fusarium strains and their research methods.
The properties of isolated chiral skyrmions in thin magnetic films
Creators: name: Leonov, A.O.
name: Monchesky, T.L.
name: Romming, N.
name: Kubetzka, A.
name: Bogdanov, A.N.
name: Wiesendanger, R.
Publisher: name: Milton Park : Taylor & Francis
Year: 2016
Subjects: subject: Chiral skyrmion
subject: collapse field
subject: thin films
subject: 530

description: Axisymmetric solitonic states (chiral skyrmions) were first predicted theoretically more than two decades ago. However, until recently they have been observed in a form of skyrmionic condensates (hexagonal lattices and other mesophases). In this paper we report experimental and theoretical investigations of isolated chiral skyrmions discovered in PdFe/Ir(111) bilayers two years ago by Romming et al (2013 Science 341 636). The results of spin-polarized scanning tunneling microscopy analyzed within the continuum and discrete models provide a consistent description of isolated skyrmions in thin layers. The existence region of chiral skyrmions is restricted by strip-out instabilities at low fields and a collapse at high fields. We demonstrate that the same equations describe axisymmetric localized states in all condensed matter systems with broken mirror symmetry, and thus our findings establish basic properties of isolated skyrmions common for chiral liquid crystals, different classes of noncentrosymmetric magnets, ferroelectrics, and multiferroics.
Thermal Transport in Phononic Cayley Tree Networks
Creators: name: Li, Huanan
name: Kottos, Tsampikos
name: Shapiro, Boris
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We analytically investigate the heat current $I$ and its thermal fluctuations $Δ$ in a branching network without loops (Cayley tree). The network consists of two type of harmonic masses: vertex masses $M$ placed at the branching points where phononic scattering occurs and masses $m$ at the bonds between branching points where phonon propagation take place. The network is coupled to thermal reservoirs consisting of one-dimensional harmonic chains of coupled masses $m$. Due to impedance missmatching phenomena, both ${\cal I}$ and $Δ$, are non-monotonic functions of the mass ratio $μ=M/m$. In particular, there are cases where they are strictly zero below some critical value $μ^*$.
Spectroscopy of CASSOWARY gravitationally-lensed galaxies in SDSS: characterisation of an extremely bright reionization-era analog at $z=1.42$
Creators: name: Mainali, Ramesh
name: Stark, Daniel P.
name: Jones, Tucker
name: Ellis, Richard S.
name: Hezaveh, Yashar D.
name: Rigby, Jane R.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present new observations of sixteen bright ($r=19-21$) gravitationally lensed galaxies at $z\simeq 1-3$ selected from the CASSOWARY survey. Included in our sample is the $z=1.42$ galaxy CSWA-141, one of the brightest known reionization-era analogs at high redshift (g=20.5), with a large sSFR (31.2 Gyr$^{-1}$) and an [OIII]+H$β$ equivalent width (EW$_{\rm{[OIII]+Hβ}}$=730~Å) that is nearly identical to the average value expected at $z\simeq 7-8$. In this paper, we investigate the rest-frame UV nebular line emission in our sample with the goal of understanding the factors that regulate strong CIII] emission. Whereas most of the sources in our sample show weak UV line emission, we find elevated CIII] in the spectrum of CSWA-141 (EW$_{\rm{CIII]}}$=4.6$\pm1.9$~Å) together with detections of other prominent emission lines (OIII], Si III], Fe II$^\star$, Mg II). We compare the rest-optical line properties of high redshift galaxies with strong and weak CIII] emission, and find that systems with the strongest UV line emission tend to have young stellar populations and nebular gas that is moderately metal-poor and highly ionized, consistent with trends seen at low and high redshift. The brightness of CSWA-141 enables detailed investigation of the extreme emission line galaxies which become common at $z>6$. We find that gas traced by the CIII] doublet likely probes higher densities than that traced by [OII] and [SII]. Characterisation of the spectrally resolved Mg II emission line and several low ionization absorption lines suggests neutral gas around the young stars is likely optically thin, potentially facilitating the escape of ionizing radiation.
description: 20 pages, 9 figures, Accepted for publication in MNRAS
Topical Review: Extracting Molecular Frame Photoionization Dynamics from Experimental Data
Creators: name: Hockett, Paul
Publisher: name: figshare
Year: 2022
Subjects: subject: 20201 Atomic and Molecular Physics
subject: FOS: Physical sciences
subject: 20603 Quantum Information, Computation and Communication
subject: Quantum Mechanics

description: Resources to accompany the manuscript Topical Review: Extracting Molecular Frame Photoionization Dynamics from Experimental Data (August 2022).
 HTML version on Authorea (with interactive figures). arXiv PDF: http://arxiv.org/abs/2209.04301. See readme.txt for more details.
The contribution of cis- and trans-regulatory variation associated with life-history shift in Arabidopsis
Creators: name: Calic, Irina
name: He, Fei
name: Maroua Bouzid Elkhessairi
name: Takou, Margarita
name: De Meaux, Juliette
Publisher: name: Zenodo
Year: 2023
Subjects: life-history shift, expression differences, regulatory changes, immunity genes

description: Shifts in life-history can alter the balance between costs and benefits of host defense systems. Shorter life cycle reduces the probability to encounter plant pathogens, while long lived species often display stronger herbivore defenses. Within Arabidopsis thaliana, a low expression of immunity genes has been associated with early flowering. Here, we examine whether fast cycling in A. thaliana is associated with the cis-regulatory rewiring of immunity-related genes. F1 hybrids were generated by crossing between A. thaliana reference ColFri and A. lyrata MN47, to minimize developmental differences between species. We analyzed the significance of gene expression variation across developmental stages and species for parental and hybrid transcriptome. We determined the contribution of cis-acting regulatory changes in life-history shift and used gene enrichment analysis to evaluate whether immunity was a preferential target of polygenic adaptation in the short-lived A. thaliana lineage.
Closed-form stochastic solutions for non-equilibrium dynamics and inheritance of cellular components over many cell divisions
Creators: name: Johnston, Iain G.
name: Jones, Nick S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Applications (stat.AP)
subject: FOS: Biological sciences
subject: FOS: Computer and information sciences

description: Stochastic dynamics govern many important processes in cellular biology, and an underlying theoretical approach describing these dynamics is desirable to address a wealth of questions in biology and medicine. Mathematical tools exist for treating several important examples of these stochastic processes, most notably gene expression, and random partitioning at single cell divisions or after a steady state has been reached. Comparatively little work exists exploring different and specific ways that repeated cell divisions can lead to stochastic inheritance of unequilibrated cellular populations. Here we introduce a mathematical formalism to describe cellular agents that are subject to random creation, replication, and/or degradation, and are inherited according to a range of random dynamics at cell divisions. We obtain closed-form generating functions describing systems at any time after any number of cell divisions for binomial partitioning and divisions provoking a deterministic or random, subtractive or additive change in copy number, and show that these solutions agree exactly with stochastic simulation. We apply this general formalism to several example problems involving the dynamics of mitochondrial DNA (mtDNA) during development and organismal lifetimes.
Farmers Field School on Taro:Bridge The Gap Between Research and Farmers' practices
Creators: name: Zulhairil, Ariffin
name: Nor, Asiah Ismail
name: Anuar, Rasyidi Mohd Nordin
name: Nurshahidah, Mohd Rusli
Publisher: name: ITPGRFA
Year: 2022
Subjects: ITPGRFA-BSF
MYS
Taro
PR-77
Farmers communities
Markets
Farmers practices
Farmers
Sustainable agriculture
Gender
On-farm conservation

description: This brochure is a visual and comprehensive visualization of the different elements of the successful approach of FFS on taro (Colocasia esculenta) model that the farmers conducted at Sabak Bernam, Selangor. Taro, also known as ‘keladi’, is cultivated by smallholders or farmers for its edible corms. This include presenting the methodology used, the baseline survey, development of training manuals and guidelines, implementation of Farmers fieled schools and presents the main findings, including sociological and ecocomic impact.

The brochure was developed  as part of the project Conservation and Sustainable Utilization of the underutilized Taro to Increase Food Security and Livelihood of Marginalized Communities Faced with Climate Change funded in the 4th cycle of the Benefit Sharing Fund (BSF) of the International Treaty on Plant Genetic Treaty on Plant Genetic Resources for Food and Agriculture (ITPGRFA) of the Food and Agriculture Organization (FAO).
On the orbit spaces of irreducible representations of simple compact Lie groups of types B, C, and D
Creators: name: Styrt, O. G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Geometry (math.AG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 22E46, 17B10, 17B20, 17B45

description: It is proved that the orbit space of an irreducible representation of a simple connected compact Lie group of type B, C, or D can be a smooth manifold only in two cases.
Evaluation of a COVID-19 convalescent plasma program at a U.S. academic medical center
Creators: name: Nelson, B.G.
name: Markmann, A.J.
name: Gilleskie, M.
name: van Duin, D.
name: Lu, C.-H.
name: Fischer, W.A.
name: de Silva, A.M.
name: Park, Y.A.
name: Herce, M.E.
name: Barzin, A.H.
name: Johnson, W.
name: Lachiewicz, A.M.
name: Gilmore, A.
name: Evans, M.
name: Weiss, S.
name: Baric, R.
name: Root, H.B.
name: Napravnik, S.
name: Wohl, D.A.
name: Bartelt, L.A.
name: Gurney, B.
name: Margolis, D.M.
name: Kuruc, J.
Publisher: name: Public Library of Science
Year: 2022

description: Amidst the therapeutic void at the onset of the COVID-19 pandemic, a critical mass of scientific and clinical interest coalesced around COVID-19 convalescent plasma (CCP). To date, the CCP literature has focused largely on safety and efficacy outcomes, but little on implementation outcomes or experience. Expert opinion suggests that if CCP has a role in COVID-19 treatment, it is early in the disease course, and it must deliver a sufficiently high titer of neutralizing antibodies (nAb). Missing in the literature are comprehensive evaluations of how local CCP programs were implemented as part of pandemic preparedness and response, including considerations of the core components and personnel required to meet demand with adequately qualified CCP in a timely and sustained manner. To address this gap, we conducted an evaluation of a local CCP program at a large U.S. academic medical center, the University of North Carolina Medical Center (UNCMC), and patterned our evaluation around the dimensions of the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to systematically describe key implementation-relevant metrics. We aligned our evaluation with program goals of reaching the target population with severe or critical COVID-19, integrating into the structure of the hospital-wide pandemic response, adapting to shifting landscapes, and sustaining the program over time during a compassionate use expanded access program (EAP) era and a randomized controlled trial (RCT) era. During the EAP era, the UNCMC CCP program was associated with faster CCP infusion after admission compared with contemporaneous affiliate hospitals without a local program: median 29.6 hours (interquartile range, IQR: 21.2–48.1) for the UNCMC CCP program versus 47.6 hours (IQR 32.6–71.6) for affiliate hospitals; (P<0.0001). Sixty-eight of 87 CCP recipients in the EAP (78.2%) received CCP containing the FDA recommended minimum nAb titer of ≥1:160. CCP delivery to hospitalized patients operated with equal efficiency regardless of receiving treatment via a RCT or a compassionate-use mechanism. It was found that in a highly resourced academic medical center, rapid implementation of a local CCP collection, treatment, and clinical trial program could be achieved through redeployment of highly trained laboratory and clinical personnel. These data provide important pragmatic considerations critical for health systems considering the use of CCP as part of an integrated pandemic response.
Protein identity and environmental parameters determine the final physico-chemical properties of protein-coated metal nanoparticles
Creators: name: Dewald, Inna
name: Isakin, Olga
name: Schubert, Jonas
name: Kraus, Tobias
name: Chanana, Munish
Publisher: name: Washington D.C. : American Chemical Society
Year: 2015
Subjects: subject: 570

description: When a nanomaterial enters a biological system, proteins adsorb onto the particle surface and alter the surface properties of nanoparticles, causing drastic changes in physico-chemical properties such as hydrodynamic size, surface charge and aggregation state, thus giving a completely new and undefined physico-chemical identity to the nanoparticles. In the present work, we study the impact of the protein identity (molecular weight and isoelectric point) and the environmental conditions (pH and ionic strength) on the final physico-chemical properties of a model nanoparticle system, i.e. gold nanoparticles. Gold nanoparticles either form stable dispersions or agglomerate spontaneously when mixed with protein solutions, depending on the protein and the experimental conditions. Strikingly, the agglomerates redisperse to individually dispersed and colloidally stable nanoparticles, depending on the purification pH. The final protein coated nanoparticles exhibit specific stabilities and surface charges that depend on protein type and the conditions during its adsorption. By understanding the interactions of nanoparticles with proteins under controlled conditions, we can define the protein corona of the NPs and thus their physico-chemical properties in various media.
Experiences pertaining to child nutrition and care provision among early care and education stakeholders, sponsors, and center directors during the COVID-19 pandemic: A multi-method study
Creators: name: Erinosho, T.
name: Jana, B.
name: Loefstedt, K.
name: Ward, D.
name: Vu, M.
Publisher: name: Frontiers Media S.A.
Year: 2022

description: Purpose: This study used multiple methods (interviews, survey) to assess experiences of stakeholders, sponsors, and center-based early care and education (ECE) program directors pertaining to child nutrition (e.g., provision of nutritious foods, mealtime practices, CACFP administration/use) and the provision of child-care (i.e., day-to-day ECE operations and programming) during the COVID-19 pandemic. Methods: Participants included stakeholders from 22 national and state agencies associated with the Child and Adult Care Food Program (CACFP) who also work to promote nutrition and quality child-care, representatives of 17 CACFP sponsor organizations, and 40 center-based ECE program directors who participated in interviews, as well as 100 ECE directors who completed surveys. Data were collected across four states. Thematic analyses of interviews and descriptive methods were used to analyze data collected. Results: Six main themes emerged from stakeholders, sponsors, and ECE program directors' focusing on: experiences during the temporary closure of several ECE programs; additional responsibilities and unanticipated expenses for ECE programs; difficulty in keeping up with constantly changing COVID-19 guidance; encounters during shifts from in-person to virtual training and monitoring; changes to nutrition practices at ECE; and the need to prioritize ECE funding. Conclusions: Findings highlight challenges and supports to ECE programs and could inform future efforts to enhance child-care quality and child nutrition in the U.S. during pandemic situations.
Kostentransparenz und Informationsbudget: Projekte, Initiativen und Infrastrukturen, die die finanzielle Dimension der OA-Transformation in den Blick nehmen
Creators: name: Schön, Margit
name: Barbers, Irene
name: Ferguson, Lea Maria
name: Meistring, Marcel
name: Schultze-Motel, Paul
Publisher: name: Zenodo
Year: 2023
Subjects: Open-Access-Transformation
Informationsbudget
Kostentransparenz

description: Die Open-Access-Transformation stellt wissenschaftliche Einrichtungen in Deutschland vor die Herausforderung, zentral und dezentral anfallende Kosten für das Publizieren und die Literaturversorgung systematisch zu erfassen und auszuwerten. Dafür werden geeignete Werkzeuge benötigt und Prozesse für ein transparentes Publikations- und Kostenmonitoring müssen angepasst oder entwickelt werden. Die auf dem Poster dargestellten Projekte und Initiativen setzen sich mit der Forderung nach einem transparenten Kosten- und Publikationsmonitoring im Kontext der Open-Access-Transformation auseinander. Sie entwickeln Werkzeuge und Strategien für transparente Prozesse.
Convex mixed integer nonlinear programming problems and an outer approximation algorithm
Creators: name: Wei, Zhou
name: Ali, M. Montaz
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: In this paper, we mainly study one class of convex mixed-integer nonlinear programming problems (MINLPs) with non-differentiable data. By dropping the differentiability assumption, we substitute gradients with subgradients obtained from KKT conditions, and use the outer approximation method to reformulate convex MINLP as one equivalent MILP master program. By solving a finite sequence of subproblems and relaxed MILP problems, we establish an outer approximation algorithm to find the optimal solution of this convex MINLP. The convergence of this algorithm is also presented. The work of this paper generalizes and extends the outer approximation method in the sense of dealing with convex MINLPs from differentiable case to non-differentiable one.
description: 16 pages
Additional file 1 of Improved therapeutic consistency and efficacy of CD317+ MSCs through stabilizing TSG6 by PTX3
Creators: name: Shi, Shaoquan
name: Chen, Si
name: Liang, Bowei
name: Li, Yumeng
name: Ma, Qi
name: Li, Meiqi
name: Zhang, Jingting
name: Yao, Lan
name: Xu, Jianyong
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 1: Table S1. Primers and shRNAs. Table S2. Seq-analysis inflomation. Table S3. Cluster markers top20. Table S4. Immunogenes list. Table S5. DEGs of CD317posi_vs_nega
spirit checklist for A comprehensive rehabilitation protocol in a post-operative case of ASD closure along with PAPVC – A Rare case report.
Creators: name: Vardhan, Vishnu
name: Choubisa, Chitrakshi
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 420106
subject: Physiotherapy

description: Spirit checklist for A comprehensive rehabilitation protocol in a post-operative case of ASD closure along with PAPVC – A Rare case report.
Spatial distribution and optical properties of Saharan dust observed by airborne high spectral resolution lidar during SAMUM 2006
Creators: name: Esselborn, Michael
name: Wirth, Martin
name: Fix, Andreas
name: Weinzierl, Bernadett
name: Rasp, Katharina
name: Tesche, Matthias
name: Petzold, Andreas
Publisher: name: Milton Park : Taylor & Francis
Year: 2017
Subjects: subject: aerosol property
subject: backscatter
subject: dust
subject: extinction coefficient
subject: lidar
subject: measurement method
subject: sea level
subject: spatial distribution
subject: spectral resolution
subject: 550

description: Airborne measurements of pure Saharan dust extinction and backscatter coefficients, the corresponding lidar ratio and the aerosol optical thickness (AOT) have been performed during the Saharan Mineral Dust Experiment 2006, with a high spectral resolution lidar. Dust layers were found to range from ground up to 4–6 km above sea level (asl). Maximum AOT values at 532 nm, encountered within these layers during the DLR Falcon research flights were 0.50–0.55. A significant horizontal variability of the AOT south of the High Atlas mountain range was observed even in cases of a well-mixed dust layer. High vertical variations of the dust lidar ratio of 38–50 sr were observed in cases of stratified dust layers. The variability of the lidar ratio was attributed to dust advection from different source regions. The aerosol depolarization ratio was about 30% at 532 nm during all measurements and showed only marginal vertical variations.
Additional file 1 of Systems for rating bodies of evidence used in systematic reviews of air pollution exposure and reproductive and children’s health: a methodological survey
Creators: name: Michel, Sophie K. F.
name: Atmakuri, Aishwarya
name: von Ehrenstein, Ondine S.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Material S1. Preferred Reporting Items for Overviews of Reviews (PRIOR) checklist. Material S2. Full electronic search strategies. Material S3. Details of ROBIS assessment: Risk of bias assessment results for each systematic review. Material S4. Details of ROBIS assessment: Responses to each question of the ROBIS tool.