cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Intradialytic Blood Pressure Abnormalities: The Highs, The Lows and All That Lies Between
Creators: name: Flythe, Jennifer E.
name: Assimon, Magdalene M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Frequent blood pressure (BP) measurements are necessary to ensure patient safety during hemodialysis (HD) treatments. Intradialytic BPs are not optimal diagnostic tools for hypertension and cardiovascular risk stratification, but they do have critical clinical and prognostic significance. We present evidence associating intradialytic BP phenomena including fall, rise, and variability with adverse clinical outcomes and review related pathophysiologic mechanisms and potential management strategies.
Torsion induced effects in magnetic nanowires
Creators: name: Sheka, Denis D.
name: Kravchuk, Volodymyr P.
name: Yershov, Kostiantyn V.
name: Gaididei, Yuri
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Magnetic helix wire is one of the most simple magnetic systems which manifest properties of both curvature and torsion. There exist two equilibrium states in the helix wire with easy-tangential anisotropy: a quasi-tangential magnetization distribution in case of relatively small curvatures and torsions, and an onion state in opposite case. In the last case the magnetization is close to tangential one, deviations are caused by the torsion and curvature. Possible equilibrium magnetization states in the helix magnet with different anisotropy directions are studied theoretically. The torsion also essentially influences the spin-wave dynamics, acting as an effective magnetic field. Originated from the curvature induced effective Dzyaloshinskii interaction, this magnetic field leads to the coupling between the helix chirality and the magnetochirality, it breaks mirror symmetry in spin-wave spectrum. All analytical predictions on magnetization statics an dynamics are well confirmed by the direct spin lattice simulations.
description: RevTeX, 14 pages, 7 figures
All-sky reconstruction of the primordial scalar potential from WMAP temperature data
Creators: name: Dorn, Sebastian
name: Greiner, Maksim
name: Enßlin, Torsten A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: An essential quantity required to understand the physics of the early Universe, in particular the inflationary epoch, is the primordial scalar potential $Φ$ and its statistics. We present for the first time an all-sky reconstruction of $Φ$ with corresponding $1σ$-uncertainty from WMAP's cosmic microwave background (CMB) temperature data -- a map of the very early Universe right after the inflationary epoch. This has been achieved by applying a Bayesian inference method that separates the whole inverse problem of the reconstruction into many independent ones, each of them solved by an optimal linear filter (Wiener filter). In this way, the three-dimensional potential $Φ$ gets reconstructed slice by slice resulting in a thick shell of nested spheres around the comoving distance to the last scattering surface. Each slice represents the primordial scalar potential $Φ$ projected onto a sphere with corresponding distance. Furthermore, we present an advanced method for inferring $Φ$ and its power spectrum simultaneously from data, but argue that applying it requires polarization data with high signal-to-noise levels not available yet. Future CMB data should improve results significantly, as polarization data will fill the present $\ell-$blind gaps of the reconstruction.
Die "Theologik" von Hans Urs von Balthasar
Creators: name: Štrukelj, Anton
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 22 Nr. 6 (1993): Internationale katholische Zeitschrift Communio, Band 22, Heft 6
Chromogenic detection of fluoride, dihydrogen phosphate, and arsenite anions based on 2,4-dinitrophenyl hydrazine receptors: spectral and electrochemical study
Creators: name: K, Nagaraj
name: Singh, Archana
name: Shetty, A. Nityananda
name: Trivedi, Darshak R.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Computational Biology

description: The colorimetric recognition of biologically relevant fluoride (F−), acetate (AcO−), and dihydrogen phosphate (H2PO4−) ions, and poisonous arsenite (AsO2−) ions, was devised and new receptors for these anions synthesised via the Schiff base condensation procedure. UV–visible titration, fluorescence titration, 1H-NMR titration, and cyclic voltammetry were used to explore the interactions of receptors R1–R3 with anions and possible detection mechanisms. The synthesised probes could sense inorganic fluoride, acetate, dihydrogen phosphate, and arsenite in the organo–aqueous medium (H2O/ Dimethylsulphoxide, 1: 9, v/v) and displayed a change in colour detectable to the naked eye. Out of the three synthesised receptors, receptor R1 showed better sensing ability of fluoride, acetate, dihydrogen phosphate, and arsenite ions in the organo–aqueous medium with a lower detection limit of 0.1 ppm, 0.171 ppm, 0.194 ppm, and 0.144 ppm, respectively. All three receptors formed complexes with the anions through H-bonding interaction followed by deprotonation of the NH proton.
Trends in Anemia Management in Hemodialysis Patients with Cancer
Creators: name: Wheeler, Stephanie B.
name: Butler, Anne M.
name: Olshan, Andrew F.
name: Nielsen, Matthew E.
name: Brookhart, M. Alan
name: Kshirsagar, Abhijit V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Erythropoiesis-stimulating agents (ESAs), intravenous iron, and blood transfusion are used to treat anemia in both end-stage renal disease (ESRD) and cancer. However, anemia treatment patterns have not been described among ESRD patients undergoing hemodialysis with concurrent cancer, especially in the recent era of ESA-related safety concerns.
Efficacy of Budesonide vs Fluticasone for Initial Treatment of Eosinophilic Esophagitis in a Randomized Controlled Trial
Creators: name: Shaheen, N.J.
name: McGee, S.J.
name: Dellon, E.S.
name: Tylicki, A.E.
name: Arrington, A.
name: Shoyoye, S.O.
name: Martin, C.F.
name: Covington, J.
name: Woosley, J.T.
name: Galanko, J.A.
name: Gebhart, J.H.
name: Moist, S.E.
name: Baron, J.A.
Publisher: name: W.B. Saunders
Year: 2019

description: Background and Aims: Topical steroid treatments for eosinophilic esophagitis (EoE) include swallowed fluticasone from a multi-dose inhaler (MDI) or oral viscous budesonide (OVB) slurry, but the 2 have never been compared. We assessed whether OVB was more effective than MDI for initial treatment of patients with EoE. Methods: In a double-blind, double-dummy trial, patients with a new diagnosis of EoE were randomly assigned to groups given 8 weeks of either OVB (1 mg/4 mL) twice daily plus a placebo inhaler (n = 56) or fluticasone MDI (880 μg) twice daily plus a placebo slurry (n = 55). Primary outcomes were post-treatment maximum eosinophil counts per high-power field (eos/hpf) and a validated dysphagia score (dysphagia symptom questionnaire [DSQ]) at week 8. Secondary outcomes included endoscopic severity (validated EoE endoscopic reference score), histologic response (<15 eos/hpf), and safety. Results: In a modified intention-to-treat analysis, the subjects had baseline peak eosinophil counts of 73 and 77 eos/hpf in the OVB and MDI groups, respectively, and DSQ scores of 11 and 8. Post-treatment eosinophil counts were 15 and 21 in the OVB and MDI groups, respectively (P =.31), with 71% and 64% achieving histologic response (P =.38). DSQ scores were 5 and 4 in the OVB and MDI groups (P =.70). Similar trends were noted for post-treatment total EoE endoscopic reference scores (2 vs 3; P =.06). Esophageal candidiasis developed in 12% of patients receiving OVB and 16% receiving MDI; oral thrush was observed in 3% and 2%, respectively. Conclusions: In a randomized clinical trial, initial treatment of EoE with either OVB or fluticasone MDI produced a significant decrease in esophageal eosinophil counts and improved dysphagia and endoscopic features. However, OVB was not superior to MDI, so either is an acceptable treatment for EoE. ClinicalTrials.gov ID NCT02019758.
Non-Perturbative Calculation of the Scalar Yukawa Theory in Four-Body Truncation
Creators: name: Li, Yang
name: Karmanov, V. A.
name: Maris, P.
name: Vary, James P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The quenched scalar Yukawa theory is solved in the light-front Tamm-Dancoff approach including up to four constituents (one scalar nucleon, three scalar pions). The Fock sector dependent renormalization is implemented. By studying the Fock sector norms, we find that the lowest two Fock sectors dominate the state even in the large-coupling region. The one-body sector shows convergence with respect to the Fock sector truncation. However, the four-body norm exceeds the three-body norm at the coupling $α\approx 1.7$.
description: 8 pages, 6 figures, conference proceeding, presented at LightCone 2014, Raleigh, North Carolina. Texts are updated and typos corrected
Malignancy-Associated Vessel Tortuosity: A Computer-Assisted, MRA Study of Choroid Plexus Carcinoma in Genetically Engineered Mice
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The ability to assess tumor malignancy and to monitor treatment response non-invasively would be of value to both clinicians and animal investigators. This report describes the MR imaging characteristics of a genetically engineered mouse model of choroid plexus carcinoma (CPC) during tumor growth and progression to malignancy. We assess the ability of vessel tortuosity measurements, as calculated from high-resolution MRA images, to detect emerging CPC cancers.
Noncommutative field with constant background fields and neutral fermion
Creators: name: Luo, Cui-bai
name: Hou, Feng-yao
name: Cui, Zhu-fang
name: Liu, Xiao-jun
name: Zong, Hong-shi
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Introducing constant background fields into the noncommutative gauge theory, we first obtain a Hermitian fermion Lagrangian which involves a Lorentz violation term, then we generalize it to a new deformed canonical noncommutation relations for fermion field. Massless neutrino oscillation in the deformed canonical noncommutation relations is analyzed. The restriction of the noncommutative coefficients is also discussed. By comparing with the existing experimental data of conventional neutrino oscillations, the order of noncommutative deformed coefficients is given from different ways.
description: 7 pages, 0 figures
Functional Connectivity MR Imaging Reveals Cortical Functional Connectivity in the Developing Brain
Creators: name: Styner, M.
name: Lin, W.
name: Chen, Y.
name: Gerig, G.
name: Smith, J.K.
name: Biswal, B.
name: Toh, C.-H.
name: Zhu, Q.
name: Gao, W.
name: Gilmore, J.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Unlike conventional functional MR imaging where external sensory/cognitive paradigms are needed to specifically activate different regions of the brain, resting functional connectivity MR imaging acquires images in the absence of cognitive demands (a resting condition) and detects brain regions, which are highly temporally correlated. Therefore, resting functional MR imaging is highly suited for the study of brain functional development in pediatric subjects. This study aimed to determine the temporal and spatial patterns of rfc in healthy pediatric subjects between 2 weeks and 2 years of age.
Der göttliche Logos und die menschliche Vernunft beim Philosophen und Märtyrer Justin
Creators: name: Figura, Michael
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 22 Nr. 6 (1993): Internationale katholische Zeitschrift Communio, Band 22, Heft 6
Diffusion Tensor Imaging Detects Abnormalities in the Corticospinal Tracts of Neonates with Infantile Krabbe Disease
Creators: name: Escolar, M.L.
name: Gilmore, J.H.
name: Lin, W.
name: Smith, J.K.
name: Poe, M.D.
name: Kurtzberg, J.
name: Styner, M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: It is not possible to determine if babies diagnosed with Krabbe disease through statewide newborn screening programs will develop disease as infants, juveniles or adults. The only available treatment for this fatal neurodegenerative condition is unrelated umbilical cord transplantation but this treatment is only effective before clinical symptoms appear. Therefore, a marker of disease progression is needed. The purpose of this study was to evaluate the use of Diffusion Tensor Imaging (DTI) with fiber tracking in identifying early changes in major motor tracts of asymptomatic neonates with infantile Krabbe disease.
Heilpädagogisches Reiten im Stundenplan von verhaltensauffälligen Schüler*innen
Creators: name: Vestner, Alessia
Publisher: name: Zenodo
Year: 2023
Subjects: Sonderpädagogik
Masterarbeit
Pferdegestützte Therapie
Verhaltensauffälligkeit
Kind
Schule

description: Die vorliegende Masterarbeit untersucht anhand einer Literaturanalyse die Wirksamkeit pferdegestützter Interventionen bei verhaltensauffälligen Schüler*innen. Ziel ist es, herauszufinden, ob pferdegestützte Interventionen geeignete Methoden sind, um diese Schüler*innen in der Schule zu unterstützen. Hierfür wurden sechs Studien analysiert und mit der Theorie zu Verhaltensauffälligkeiten und pferdegestützten Interventionen verglichen. Die Ergebnisse zeigen, dass pferdegestützte Interventionen einen Mehrwert für verhaltensauffällige Kinder bieten können. Es bleibt jedoch unklar, ob diese Ergebnisse auch auf den Schulalltag übertragbar sind. Weitere Forschung in diesem Bereich ist notwendig, um abschliessend zu klären, ob das heilpädagogische Reiten eine geeignete unterstützende Massnahme wäre und in den Stundenplan von verhaltensauffälligen Schüler*innen integriert werden sollte.
Search for a standard model Higgs boson produced in association with a top-quark pair and decaying to bottom quarks using a matrix element method
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for a standard model Higgs boson produced in association with a top-quark pair and decaying to bottom quarks is presented. Events with hadronic jets and one or two oppositely charged leptons are selected from a data sample corresponding to an integrated luminosity of 19.5 inverse femtobarns collected by the CMS experiment at the LHC in pp collisions at a centre-of-mass energy of 8 TeV. In order to separate the signal from the larger t t-bar + jets background, this analysis uses a matrix element method that assigns a probability density value to each reconstructed event under signal or background hypotheses. The ratio between the two values is used in a maximum likelihood fit to extract the signal yield. The results are presented in terms of the measured signal strength modifier, mu, relative to the standard model prediction for a Higgs boson mass of 125 GeV. The observed (expected) exclusion limit at a 95% confidence level is mu < 4.2 (3.3), corresponding to a best fit value mu-hat = 1.2 +1.6 -1.5.
description: Replaced with published version. Added journal reference and DOI
Temporal and Spatial Development of Axonal Maturation and Myelination of White Matter in the Developing Brain
Creators: name: Gerig, G.
name: Gilmore, J.H.
name: Jewells, V.
name: Lin, W.
name: Chen, Y.
name: Gao, W.
name: Smith, J.K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Diffusion tensor imaging (DTI) has been widely used to investigate the development of white matter (WM). However, information about this development in healthy children younger than 2 years of age is lacking, and most previous studies have only measured fractional anisotropy (FA). This study used FA and radial and axonal diffusivities in children younger than 2 years of age, aiming to determine the temporal and spatial development of axonal maturation and myelination of WM in healthy children.
Systematic classification of two-loop realizations of the Weinberg operator
Creators: name: Sierra, D. Aristizabal
name: Degee, A.
name: Dorame, L.
name: Hirsch, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We systematically analyze the $d=5$ Weinberg operator at 2-loop order. Using a diagrammatic approach, we identify two different interesting categories of neutrino mass models: (i) Genuine 2-loop models for which both, tree-level and 1-loop contributions, are guaranteed to be absent. And (ii) finite 2-loop diagrams, which correspond to the 1-loop generation of some particular vertex appearing in a given 1-loop neutrino mass model, thus being effectively 2-loop. From the large list of all possible 2-loop diagrams, the vast majority are infinite corrections to lower order neutrino mass models and only a moderately small number of diagrams fall into these two interesting classes. Moreover, all diagrams in class (i) are just variations of three basic diagrams, with examples discussed in the literature before. Similarly, we also show that class (ii) diagrams consists of only variations of these three plus two more basic diagrams. Finally, we show how our results can be consistently and readily used in order to construct two-loop neutrino mass models.
description: Few clarifications and references added. Matches published version in JHEP
Roseophilin-inspired derivatives as transmembrane anion carriers
Creators: name: Díaz-Cabrera, Sandra
name: Carreira-Barral, Israel
name: García-Valverde, María
name: Quesada, Roberto
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Roseophilin is an alkaloid structurally related to prodiginines . The intriguing pharmacological properties of these derivatives have prompted us to prepare synthetic compounds 1–3 inspired by their structure and to explore their transmembrane anion transport activity. The methoxyfuran heterocycle impacts the anionophoric activity of the compounds as a result of the reduced hydrogen-bonding ability and electrostatic repulsions between the oxygen in the furan ring and the anions. The position of the furan was also found to be crucial for determining their anion transport activity. Overall, replacement of the characteristic methoxypyrrole moiety of prodiginines and tambjamines by the methoxyfuran found in roseophilin is detrimental to their ability as anion carriers, suggesting that the biological activity of roseophilin is likely not related to their potential activity as anion carriers. Compound 2, bearing a furan ring attached to a dipyrromethene moiety, was found to be the most active anion carrier.
The effect of age on DNA methylation in whole blood among Bangladeshi men and women
Creators: name: Rakibuz-Zaman, M.
name: Pierce, B.L.
name: Islam, T.
name: Ahsan, H.
name: Jansen, R.J.
name: Sarwar, G.
name: Yunus, M.
name: Shahriar, H.
name: Baron, J.A.
name: Islam, M.T.
name: Rahman, M.
name: Tong, L.
name: Argos, M.
name: Kibriya, M.G.
name: Jasmine, F.
Publisher: name: BioMed Central Ltd.
Year: 2019

description: Background: It is well-known that methylation changes occur as humans age, however, understanding how age-related changes in DNA methylation vary by sex is lacking. In this study, we characterize the effect of age on DNA methylation in a sex-specific manner and determine if these effects vary by genomic context. We used the Illumina HumanMethylation 450 K array and DNA derived from whole blood for 400 adult participants (189 males and 211 females) from Bangladesh to identify age-associated CpG sites and regions and characterize the location of these age-associated sites with respect to CpG islands (vs. shore, shelf, or open sea) and gene regions (vs. intergenic). We conducted a genome-wide search for age-associated CpG sites (among 423,604 sites) using a reference-free approach to adjust for cell type composition (the R package RefFreeEWAS) and performed an independent replication analysis of age-associated CpGs. Results: The number of age-associated CpGs (p < 5 x 10-8) were 986 among men and 3479 among women of which 2027(63.8%) and 572 (64.1%) replicated (using Bonferroni adjusted p < 1.2 × 10-5). For both sexes, age-associated CpG sites were more likely to be hyper-methylated with increasing age (compared to hypo-methylated) and were enriched in CpG islands and promoter regions compared with other locations and all CpGs on the array. Although we observed strong correlation between chronological age and previously-developed epigenetic age models (r ≈ 0.8), among our top (based on lowest p-value) age-associated CpG sites only 12 for males and 44 for females are included in these prediction models, and the median chronological age compared to predicted age was 44 vs. 51.7 in males and 45 vs. 52.1 in females. Conclusions: Our results describe genome-wide features of age-related changes in DNA methylation. The observed associations between age and methylation were generally consistent for both sexes, although the associations tended to be stronger among women. Our population may have unique age-related methylation changes that are not captured in the established methylation-based age prediction model we used, which was developed to be non-tissue-specific.
Reduced Mortality and Severe Disability Rates in the SENTIS Trial
Creators: name: Leker, R.R.
name: Jovin, T.
name: Saver, J.L.
name: Liebeskind, D.S.
name: Schellinger, P.D.
name: Huang, D.Y.
name: Hammer, M.D.
name: Shuaib, A.
name: Sen, S.
name: Gupta, R.
name: Köhrmann, M.
name: Solander, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The Safety and Efficacy of NeuroFlo Technology in Ischemic Stroke trial showed a trend for reduced all-cause mortality and positive secondary safety end point outcomes. We present further analyses of the mortality and severe disability data from the Safety and Efficacy of NeuroFlo Technology in Ischemic Stroke trial.
Symmetry-plane model of 3D Euler flows and mapping to regular systems to improve blowup assessment using numerical and analytical solutions
Creators: name: Mulungye, Rachel M.
name: Lucas, Dan
name: Bustamante, Miguel D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Motivated by the work on stagnation-point type exact solutions (with infinite energy) of 3D Euler fluid equations by Gibbon et al. (1999) and the subsequent demonstration of finite-time blowup by Constantin (2006) we introduce a one-parameter family of models of the 3D Euler fluid equations on a 2D symmetry plane. Our models are seen as a deformation of the 3D Euler equations which respects the variational structure of the original equations so that explicit solutions can be found for the supremum norms of the basic fields. The value of the model's parameter determines if there is finite-time blowup, and the singularity time can be computed explicitly in terms of the initial conditions and the model's parameter. We use a representative parameter value, for which the solution blows up in finite-time, as a benchmark for the systematic study of errors in numerical solutions. We compare numerical integrations of our "original" model with a "mapped" version of these equations. The mapped version is a globally regular (in time) system of equations, obtained via a bijective nonlinear mapping of time and fields from the original model equations (Bustamante 2011). We show that the mapped system's numerical solution increases accuracy in estimates of supremum norms and singularity time while entailing only a small additional computational cost. We study the Fourier spectrum of the model's numerical solution and find that the analyticity-strip width (a measure of the solution's analyticity) tends to zero as a power law in a finite time. This is in agreement with the finite-time blowup of the supremum norms, in the light of rigorous bounds stemming from the bridge (Bustamante & Brachet 2012) between the analyticity-strip method and the Beale-Kato-Majda type of theorems. We conclude by discussing the implications of this research on the analysis of numerical solutions of the 3D Euler fluid equations.
The Kety-Schmidt Technique for Quantitative Perfusion and Oxygen Metabolism Measurements in the MR Imaging Environment
Creators: name: Powers, W.J.
name: Lee, J.J.
name: Derdeyn, C.P.
name: Faulkner, C.B.
name: Boyle, P.J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The Kety-Schmidt technique provides quantitative measurement of whole brain cerebral blood flow (CBF). CBF is measured as the area between the arterial and venous washout curves of a diffusible tracer. Oxygen extraction and metabolism may be calculated from arterial and venous samples. In this report we present a method for performing these measurements in an MR environment. This technique could be useful for validation of MR methods of hemodynamic and metabolic measurements in humans.
Family history of colorectal cancer in first-degree relatives and metachronous colorectal adenoma
Creators: name: Lieberman, D.A.
name: Jacobs, E.T.
name: Gupta, S.
name: Cross, A.J.
name: Martínez, M.E.
name: Murphy, G.
name: Baron, J.A.
Publisher: name: Nature Publishing Group
Year: 2018

description: Objectives: Little is known about the relationship between having a first-degree relative (FDR) with colorectal cancer (CRC) and risk for metachronous colorectal adenoma (CRA) following polypectomy. Methods: We pooled data from seven prospective studies of 7697 patients with previously resected CRAs to quantify the relationship between having a FDR with CRC and risk for metachronous adenoma. Results: Compared with having no family history of CRC, a positive family history in any FDR was significantly associated with increased odds of developing any metachronous CRA (OR = 1.14; 95% CI = 1.01-1.29). Higher odds of CRA were observed among individuals with an affected mother (OR = 1.27; 95% CI = 1.05-1.53) or sibling (OR = 1.34; 95% CI = 1.11-1.62) as compared with those without, whereas no association was shown for individuals with an affected father. Odds of having a metachronous CRA increased with number of affected FDRs, with ORs (95% CIs) of 1.07 (0.93-1.23) for one relative and 1.39 (1.02-1.91) for two or more. Younger age of diagnosis of a sibling was associated with higher odds of metachronous CRA, with ORs (95% CIs) of 1.66 (1.08-2.56) for diagnosis at <54 years; 1.34 (0.89-2.03) for 55-64 years; and 1.10 (0.70-1.72) for >65 years (p-trend = 0.008). Although limited by sample size, results for advanced metachronous CRA were similar to those for any metachronous CRA. Conclusions: A family history of CRC is related to a modestly increased odds of metachronous CRA. Future research should explore whether having a FDR with CRC, particularly at a young age, should have a role in risk stratification for surveillance colonoscopy.
Correlates of intake of folic acid–containing supplements among pregnant women
Creators: name: Herring, A.
name: Shaw, G.M.
name: Laurent, C.
name: Royle, Marjorie H.
name: Yang, W.
name: Carmichael, S.L.
name: Canfield, M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: This study describes the timing and correlates of folic acid supplement intake among pregnant women.
Preliminary Results of Measurements of Frontal Plane Knee Alignment Using a Standardized, Sonographic-Assisted Digital Photograph—A Reliable and Accurate Alternative to a Full-Leg Radiograph?
Creators: name: Memmel, Clemens
name: Meier, Christoph
name: Huber, Lorenz
name: Szymski, Dominik
name: Achenbach, Leonard
name: Koch, Matthias
name: Alt, Volker
name: Krutsch, Werner
name: Weber, Johannes
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: knee alignment; clinical measurement; hip–knee–ankle angle; full-leg radiograph
subject: 610 Medizin

description: (1) Clinical alternatives to the full-leg radiograph (FLR) for determining frontal plane lower limb alignment have shown mixed results so far concerning reliability and accuracy. In addition, intercondylar respectively intermalleolar distance (ICD/IMD) measurement is limited in the interpretation of its results. The purpose of the study is to present a standardized, sonographic-assisted photographic measurement (SPM) of the leg axis in the frontal plane using a digital photograph and compare it with the gold standard of the anterior–posterior FLR. (2) Adults who had recently received an FLR were included in the study. After determining the center of the hip joint and knee joint gap in a standing position via ultrasound, a standardized digital photograph was taken. Subsequently, the hip–knee–ankle angle (HKA) was measured using an image editing program for SPM and FLRs. Mean deviation (MD), Pearson’s correlation coefficient and the clinical method’s interclass correlation coefficient (ICC) were calculated. (3) Of 18 subjects (8 male and 10 female), respectively, 34 lower extremities have been included in the study. Their mean BMI was 25.5 kg/m2. The correlation between the two measurement methods for subjects with BMI < 30 kg/m2 was reliably high (r = 0.93, p < 0.001). The HKAs derived from SPM and FLRs showed a mean deviation (MD) of 2.4° (range 0.1–6.0°) for subjects with BMI < 30 kg/m2. The average ICC among all examiners conducting the SPM was 0.99 (CI 0.95–0.99, p < 0.001). The MD for subjects ≥ 30 kg/m2 increased significantly (MD = 5.5°; n = 10, p < 0.001). (4) SPM of the leg axis in the frontal plane allows sufficiently accurate results in patients with a BMI lower than 30 kg/m2. The methodology is limited in cases of increased BMI and needs well-trained examiners. Nevertheless, as a screening method in the field of children and adolescents, this method can be recommended in clinical daily routine.
Chancen und Herausforderungen des Nachteilsausgleiches sowie dessen Auswirkungen auf die Motivation von Schülerinnen und Schülern mit einer Lernstörung
Creators: name: Schmid, Fabienne
Publisher: name: Zenodo
Year: 2023
Subjects: Sonderpädagogik
Masterarbeit
Nachteilsausgleich
Berufsschule
Motivation

description: Das Thema Nachteilsausgleich befasst sich mit Unterstützungsmöglichkeiten für benachteiligte oder eingeschränkte Personen, um allen eine faire Chance auf angemessene Bildung zu ermöglichen. Folgende Arbeit untersucht, wie die Umsetzung bei Betroffenen ankommt, ob Verbesserungen im System erforderlich sind und wie die Unterstützung die motivationale Lage der Schüler*innen beeinflusst. Sechs Interviews mit betroffenen Berufsschülern wurden mittels qualitativer Inhaltsanalyse ausgewertet. Es zeigt sich wie wichtig das Verständnis über den Zweck der Massnahmen für eine Steigerung der Motivation ist. Es hat sich aber auch herausgestellt, dass die Schaffung von fairen Bedingungen im Schulalltag nicht nur Chancen mit sich bringt. Lernende, die fachkompetent unterstützt werden, sind dankbar für den Nachteilsausgleich. Eine flächendeckende Ausdehnung des Nachteilsausgleichs auf alle Betroffenen ist wünschenswert, erfordert jedoch die notwendigen Aufklärungsarbeiten und Mittel.
Low-Dose Aspirin Use Does Not Increase Survival in 2 Independent Population-Based Cohorts of Patients With Esophageal or Gastric Cancer
Creators: name: Spence, A.D.
name: Johnston, B.T.
name: Coleman, H.G.
name: Hughes, C.M.
name: Baron, J.A.
name: Busby, J.
name: Cardwell, C.R.
Publisher: name: W.B. Saunders
Year: 2018

description: Background & Aims: Preclinical studies have shown aspirin to have anticancer properties and epidemiologic studies have associated aspirin use with longer survival times of patients with cancer. We studied 2 large cohorts to determine the association between aspirin use and cancer-specific mortality in patients with esophageal or gastric cancer. Methods: We performed a population-based study using cohorts of patients newly diagnosed with esophageal or gastric cancer, identified from cancer registries in England from 1998 through 2012 and the Scottish Cancer Registry from 2009 through 2012. Low-dose aspirin prescriptions were identified from linkages to the United Kingdom Clinical Research Practice Datalink in England and the Prescribing Information System in Scotland. Deaths were identified from linkage to national mortality records, with follow-up until September 2015 in England and January 2015 in Scotland. Time-dependent Cox regression models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for cancer-specific mortality by low-dose aspirin use after adjusting for potential confounders. Meta-analysis was used to pool results across the 2 cohorts. Results: The combined English and Scottish cohorts contained 4654 patients with esophageal cancer and 3833 patients with gastric cancer, including 3240 and 2392 cancer-specific deaths, respectively. The proportions surviving 1 year, based on cancer-specific mortality, were similar in aspirin users vs non-users after diagnosis with esophageal cancer (48% vs 50% in England and 49% vs 46% in Scotland, respectively) or gastric cancer (58% vs 57% in England and 59% vs 55% in Scotland, respectively). There was no association between postdiagnosis use of low-dose aspirin and cancer-specific mortality among patients with esophageal cancer (pooled adjusted HR, 0.98; 95% CI, 0.89–1.09) or gastric cancer (pooled adjusted HR, 0.96; 95% CI, 0.85–1.08). Long-term aspirin use was not associated with cancer-specific mortality after diagnosis of esophageal cancer (pooled adjusted HR, 1.03; 95% CI, 0.85–1.25) or gastric cancer (pooled adjusted HR, 1.06; 95% CI, 0.85–1.32). Conclusions: In analyses of 2 large independent cohorts in the United Kingdom, low-dose aspirin usage was not associated with increased survival of patients diagnosed with esophageal or gastric cancer.
A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus
Creators: name: Sinkala, Moses
name: Kaseba, Christine
name: Stringer, Jeffrey S.A.
name: Levy, Jens
name: Vermund, Sten H.
name: Mwanahamuntu, Mulindi
name: Goldenberg, Robert L.
name: Matongo, Inutu
name: Stringer, Elizabeth M.
name: Chi, Benjamin H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The purpose of this study was to determine whether the intrauterine contraceptive device (IUD) is effective and safe among women who are infected with the human immunodeficiency virus (HIV).
On properties of Velikhov-Chandrasekhar MRI in ideal and non-ideal plasma
Creators: name: Shakura, N. I.
name: Postnov, K. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Conditions of Velikhov-Chandrasekhar magneto-rotational instability in ideal and non-ideal plasmas are examined. Linear WKB analysis of hydromagnetic axially symmetric flows shows that in the Rayleigh-unstable hydrodynamic case where the angular momentum decreases with radius, the MRI branch becomes stable, and the magnetic field suppresses the Rayleigh instability at small wavelengths. We investigate the limiting transition from hydromagnetic flows to hydrodynamic flows. The Rayleigh mode smoothly transits to the hydrodynamic case, while the Velikhov-Chandrasekhar MRI mode completely disappears without the magnetic field. The effects of viscosity and magnetic diffusivity in plasma on the MRI conditions in thin accretion discs are studied. We find the limits on the mean free-path of ions allowing MRI to operate in such discs.
description: 10 pages, 7 figures, MNRAS in press; figures 1-5 corrected, reference added
USING PROTECTED PROTEIN SOURCE SUPPLEMENTATION ON MICROORGANISMS OF RUMEN AND BIOCHEMICAL STATUS LACTATING COWS
Creators: name: Buryakov N.P., Laptev G.Yu.
Publisher: name: TuEngr Group
Year: 2020
Subjects: Animal husbandry
Lactating cows
Protein concentrate (PC)
Cattle feeding
Feed of animal origin
Feed nutrition
Blood biochemistry
Ruminal microbiome
Symbiotic microflora
Non-separable protein (NSP).

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 14, 11A14A: 1-14
Muß die katholische Kirche aus dem staatlichen Beratungssystem aussteigen?
Creators: name: Reis, Hans
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 22 Nr. 5 (1993): Internationale katholische Zeitschrift Communio, Band 22, Heft 5
An integrated electronic health record-based workflow to improve management of colonoscopy-generated pathology results
Creators: name: Galanko, J.A.
name: Chang, A.O.
name: Dorn, S.D.
name: Baron, J.A.
name: Crockett, S.D.
name: Cirri, H.O.
Publisher: name: Dove Medical Press Ltd
Year: 2018

description: Purpose: Managing and communicating colonoscopy-generated pathology results and appropriate follow-up recommendations can be challenging. To improve this process, we developed and implemented a standardized electronic health record-based intervention with built-in decision support. Methods: Fourteen attending endoscopists performed enough colonoscopies to qualify for the study. For each, we randomly sampled and abstracted data from 35 colonoscopies that met prespecified inclusion criteria during both the pre-intervention and also post-intervention periods. Follow-up recommendations were compared to guidelines. We used the Wilcoxon Signed Rank Test to assess the change in the proportion of cases with guideline-concordant results, the proportion with a documented follow-up result letter, and the median time to letter completion. A brief survey assessed endoscopists’ satisfaction with the intervention. Results: In total, 1,947 colonoscopies were extracted, of which 968 met inclusion criteria. The proportion of follow-up recommendations that were guideline concordant increased from a median of 82.9% pre-intervention to 85.7% post-intervention (P=0.72). The proportion of observations with a documented follow-up result letter increased from a median of 88.9% pre-intervention to 97.1% post-intervention (P=0.07). The number of calendar days between the date of the colonoscopy and the date the letter was sent decreased from a median of 7.7 days pre-intervention to 6.8 days post-intervention (P=0.79). Eighty-six percentage of endoscopists were either “very satisfied” or “satisfied” with the overall process. Conclusion: The intervention was not associated with a statistically significant increase in guideline-concordant recommendations or efficiency measures, perhaps due to high baseline performance. The intervention was well received by endoscopists and captured data necessary for important downstream processes.
Gastrointestinal complications following abdominal sacrocolpopexy for advanced pelvic organ prolapse
Creators: name: Brubaker, Linda
name: Gutman, Robert E.
name: Varner, R. Edward
name: Whitehead, William E.
name: Zyczynski, H.
name: Brown, Morton B.
name: Visco, Anthony G.
name: Bradley, Catherine S.
name: Weber, Anne M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The aims of this secondary analysis of the “Colpopexy And Urinary Reduction Efforts” (CARE) study were to estimate the incidence of post-operative gastrointestinal complications and identify risk factors.
Statistical work-energy theorems in deterministic dynamics
Creators: name: Kim, Chang Sub
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We theoretically explore the Bochkov-Kuzovlev-Jarzynski-Crooks work theorems in a finite system subject to external control, which is coupled to a heat reservoir. We first elaborate the mechanical energy-balance between the system and the surrounding reservoir and proceed to formulate the statistical counterpart under the general nonequilibrium conditions. Consequently, a consistency condition is derived, underpinning the nonequilibrium equalities, both in the framework of the system-centric and nonautonomous Hamiltonian pictures and its utility is examined in a few examples. Also, we elucidate that the symmetric fluctuation associated with forward and backward manipulation of the nonequilibrium work is contingent on time-reversal invariance of the underlying mesoscopic dynamics.
description: 16 pages, no figure
The global network: a prospective study of stillbirths in developing countries
Creators: name: Tshefu, Antoinette
name: Jehan, Imtiaz
name: Panigrahi, Pinaki
name: Engmann, Cyril
name: Chomba, Elwyn
name: Garces, Ana
name: McClure, Elizabeth M.
name: Hambidge, Michael
name: Derman, Richard J.
name: Wright, Linda L.
name: Althabe, Fernando
name: Parida, Sailajanandan N.
name: Goudar, Shivaprasad S.
name: Buekens, Pierre
name: Carlo, Waldemar A.
name: Harris, Hillary
name: Goldenberg, Robert L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Our goal was to determine stillbirth rates in a multi-site population-based study in community settings in the developing world.
Three decades of augmented reality in education: A second-order meta-analysis and research synthesis
Creators: name: Malone, Sarah
name: Garzón, Juan
name: Kuhn, Jochen
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Education

description: Existing literature suggest that research on educational augmented reality (AR) began three decades ago. One of the first documented development was an AR system to demonstrate elbow movement. This system was developed at the University of North Carolina at Chapel Hill in 1992 (Bajura et al., 1992) and presented in the first International Conference on Computer Vision, Virtual Reality, and Robotics in Medicine held in Nice, France, in 1995 (Kancherla, et al.1995). While for some years empirical studies on AR in education were only published sporadically, a first significant increase can be observed from the year 2009 onwards. A few years later, the first comprehensive literature reviews on AR in education were published (e.g., Bacca et al., 2014, Radu, 2014, Santos et al., 2014). In tandem with the continuously evolving technology in this field, the number of original studies has been increasing rapidly ever since. Moreover, research on AR in education is becoming increasingly differentiated, with AR being used in a variety of different teaching and learning contexts and domains (Garzón & Acevedo, 2019), and both qualitative and quantitative research methods being used to investigate the impact of AR use on different learning outcome and learning process variables (Buchner et al., 2021; Garzón et al., 2020). In addition, researchers are producing research syntheses at ever shorter intervals. Due to the enormous increase in the number of original studies, recent systematic reviews and meta-analyses are no longer as broad and inclusive as earlier research syntheses. Rather, they focus exclusively on research in selected domains (e.g., STEM education; Ibáñez & Delgado-Kloos, 2018) or for selected groups of learners (e.g., special needs; Quintero et al. 2019). Around 100 research syntheses have been published in total, some of them with a strong overlap of the included primary studies. With our second-order meta-analysis, we hope to provide a broader overview of the research landscape and summarize the results of all quantitative research syntheses on AR in education over the past 30 years.
Additional file 5: of PYK2 promotes HER2-positive breast cancer invasion
Creators: name: Shaymaa IK. Al-Juboori
name: Jayakumar Vadakekolathu
name: Sarra Idri
name: Wagner, Sarah
name: Zafeiris, Dimitrios
name: Pearson, Joshua RD.
name: Rukaia Almshayakhchi
name: Caraglia, Michele
name: Desiderio, Vincenzo
name: Miles, Amanda
name: Boocock, David
name: Ball, Graham
name: Regad, Tarik
Publisher: name: Figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: Plant Biology

description: Data S2. Tables representing top 25 upregulated proteins and top 25 downregulated proteins in SkBr3 untreated control vs. untreated and treated PYK2 knockdown samples with Fc 2 ≥ − 2, and confidence of 70%. (DOCX 26 kb)
Experimental Investigation of the Effect of Surface Roughness on a Plane Wake Using Particle Image Velocimetry
Creators: name: LAWRENCE, SEAN TIMOTHY EDWARD
Publisher: name: Monash University
Year: 2022
Subjects: Experimental methods in fluid flow, heat and mass transfer
Fluid mechanics and thermal engineering not elsewhere classified
Turbulent flows

description: This thesis describes a comprehensive set of experiments to characterise the effect of surface roughness on the wake of submerged objects. It presents a statistical analysis of the results and a novel data reconstruction method to reveal how surface roughness affects the flow over the object and the organised fluid structures in its wake.
The impact of fecal and urinary incontinence on quality of life 6 months after childbirth
Creators: name: Fitzgerald, Mary Pat
name: Borello-France, Diane
name: Zyczynski, Halina M.
name: Burgio, Kathryn L.
name: Janz, Nancy K.
name: Brown, Morton B.
name: Fine, Paul M.
name: Whitehead, William
name: Handa, Victoria L.
name: Weber, Anne M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The objective of the study was to investigate the impact of postpartum fecal incontinence (FI) and urinary incontinence (UI) on quality of life (QOL).