cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Translationally invariant multipartite Bell inequalities involving only two-body correlators
Creators: name: Tura, J.
name: Sainz, A. B.
name: Vértesi, T.
name: Acín, A.
name: Lewenstein, M.
name: Augusiak, R.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Bell inequalities are natural tools that allow one to certify the presence of nonlocality in quantum systems. The known constructions of multipartite Bell inequalities contain, however, correlation functions involving all observers, making their experimental implementation difficult. The main purpose of this work is to explore the possibility of witnessing nonlocality in multipartite quantum states from the easiest-to-measure quantities, that is, the two-body correlations. In particular, we determine all three and four-partite Bell inequalities constructed from one and two-body expectation values that obey translational symmetry, and show that they reveal nonlocality in multipartite states. Also, by providing a particular example of a five-partite Bell inequality, we show that nonlocality can be detected from two-body correlators involving only nearest neighbours. Finally, we demonstrate that any translationally invariant Bell inequality can be maximally violated by a translationally invariant state and the same set of observables at all sites. We provide a numerical algorithm allowing one to seek for maximal violation of a translationally invariant Bell inequality.
description: 21 pages, to be published in the special issue of JPA "50 years of Bell's theorem"
Additional file 2 of Duration of palliative care before death in international routine practice: a systematic review and meta-analysis
Creators: name: Jordan, Roberta I.
name: Allsop, Matthew J.
name: ElMokhallalati, Yousuf
name: Jackson, Catriona E.
name: Edwards, Helen L.
name: Chapman, Emma J.
name: Deliens, Luc
name: Bennett, Michael I.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Additional file 2: Table S1. PRISMA checklist. Table S2. Summary of characteristics of studies. Table S3. Individual study quality appraisal using Hawker’s criteria. Table S4. Summary of characteristics of studies (excluding USA data). Table S5. Duration of care with sub-analyses (excluding USA data).
Separation of acoustic waves in isentropic flow perturbations
Creators: name: Henke, Christian
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 35C20, 35L03, 35L65, 76Q05

description: The present contribution investigates the mechanisms of sound generation and propagation in the case of highly-unsteady flows. Based on the linearisation of the isentropic Navier-Stokes equation around a new pathline-averaged base flow, it is demonstrated for the first time that flow perturbations of a non-uniform flow can be split into acoustic and vorticity modes, with the acoustic modes being independent of the vorticity modes. Therefore, we can propose this acoustic perturbation as a general definition of sound. As a consequence of the splitting result, we conclude that the present acoustic perturbation is propagated by the convective wave equation and fulfils Lighthill's acoustic analogy. Moreover, we can define the deviations of the Navier-Stokes equation from the convective wave equation as true sound sources. In contrast to other authors, no assumptions on a slowly varying or irrotational flow are necessary. Using a symmetry argument for the conservation laws, an energy conservation result and a generalisation of the sound intensity are provided.
GIS As Tool For Geosite Awareness
Creators: name: Oliveira, Sónia
name: Moura, Delminda
name: Pereira, Luís
name: Veiga-Pires, Cristina
Publisher: name: Zenodo
Year: 2021
Subjects: Aspiring Geopark Algarvensis, Escarpão Plateau, Storymap, GIS

description: In the last decade there has been a focus on the dissemination of international, national, and municipal data making them available for consultation or for download and future processing by the population in GIS programs. This data is made available through Geoportals, which are portals to Internet-based geospatial resources, allowing users to discover, view and access geospatial information and services provided by a wide range of organisations. From this data there are unlimited options for analysis by users, including students and teachers, such as making maps, 3D models and other applications. One of the examples of practical applications is the development of storymaps, based on web applications that allow to tell a story in a dynamic way combining geographical maps with text and other multimedia contents. These applications are increasingly used in scientific dissemination, as well as educational tool within a wide range of themes. They have thus also great potential to enable the awareness about the geoparks and the geosites values to all the public in an interactive and appealing way. Accordingly, we developed, in the context of the Algarvensis aspiring Geopark, a Story Map regarding the walking path - PR4 Escarpão Plateau, in which the history of this geomorphological entity is told, and suggestions are made on how to explore it in several locations along the 8 km route. This digital educational resource can be used to explore the geosite during the walking route, but also as a virtual field trip in a classroom context.
Semantic structure of Kuwaiti Maritime proverbs: a Natural Semantic Metalanguage analysis
Creators: name: AlBader, Yousuf B.
name: Al-Qenaie, Shamlan D.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Kuwaiti maritime proverbs are often misinterpreted by non-native speakers due to cultural references and metaphors. This study aimed to analyse these proverbs from a semantic, rather than a folkloristic, perspective. It is the first to examine and conceptualise Kuwaiti maritime proverbs using the Natural Semantic Metalanguage (NSM) system of componential semantics, as outlined in the works of Wierzbicka and Goddard. Five maritime proverbs were analysed using simple words to express more complex meanings, with explanations built using the five-part semantic template for English and Malay proverbs proposed by Goddard (2009, 2014). A communicative translation strategy was used to translate the proverbs into English. Data for analysis were collected from three specialised dictionaries on Kuwaiti proverbs and six related to Kuwaiti maritime history and culture. The analysis revealed common themes, such as the importance of cooperation, resilience, and the unpredictability of the sea. For example, the Kuwaiti proverb ‘Two captains sank the ship’ underscores the dangers of having multiple leaders in a single endeavour, which can yield counterproductive outcomes due to a lack of coordination and singular vision. NSM helped clarify such cultural nuances, reducing misunderstanding by explicating meanings. This study contributes to a deeper understanding of Kuwaiti maritime proverbs and their cultural significance, offering a valuable tool for cross-cultural communication. The findings also highlight the challenges in pairing proverbs from different languages, posing issues in both dictionaries and second-language learning environments.
Incremental Network Design with Maximum Flows
Creators: name: Kalinowski, Thomas
name: Matsypura, Dmytro
name: Savelsbergh, Martin W. P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Discrete Mathematics (cs.DM)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: We study an incremental network design problem, where in each time period of the planning horizon an arc can be added to the network and a maximum flow problem is solved, and where the objective is to maximize the cumulative flow over the entire planning horizon. After presenting two mixed integer programming (MIP) formulations for this NP-complete problem, we describe several heuristics and prove performance bounds for some special cases. In a series of computational experiments, we compare the performance of the MIP formulations as well as the heuristics.
description: 26 pages
QFT over the finite line. Heat kernel coefficients, spectral zeta functions and selfadjoint extensions
Creators: name: Munoz-Castaneda, J. M.
name: Kirsten, Klaus
name: Bordag, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Following the seminal works of Asorey-Ibort-Marmo and Muñoz-Castañeda-Asorey about selfadjoint extensions and quantum fields in bounded domains, we compute all the heat kernel coefficients for any strongly consistent selfadjoint extension of the Laplace operator over the finite line $[0,L]$. The derivative of the corresponding spectral zeta function at $s=0$ (partition function of the corresponding quantum field theory) is obtained. In order to compute the correct expression for the $a_{1/2}$ heat kernel coefficient, it is necessary to know in detail which non-negative selfadjoint extensions have zero modes and how many of them they have. The answer to this question leads us to analyse zeta function properties for the Von Neumann-Krein extension, the only extension with two zero modes.
description: Accepted Lett. Math. Phys. Some typos have been corrected, and a reference updated
User Interactions With a Municipality Chatbot—Lessons Learnt From Dialogue Analysis
Creators: name: Følstad, Asbjørn
name: Bjerkreim-Hanssen, Nina
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: Chatbots are increasingly taken up by the public sector, as a means to efficient provision of information and services. However, there is a lack of knowledge on how users interact with such chatbots. To address this knowledge gap, we have conducted an analysis of user interactions with a chatbot for citizens of Norwegian municipalities. We analyzed a total of 2663 user-chatbot dialogues from six municipalities, using the framework of Følstad and Taylor. The analysis showed that most user input was characterized by brief messages and a utility-oriented dialogue style whereas chatbot responses were characterized by substantial response relevance (68% of chatbot responses categorized as relevant) and helpfulness (66% of dialogues categorized as help being offered and likely used). Furthermore, message brevity and a utility-oriented dialogue style was found to be positively associated with users receiving relevant chatbot responses and helpful dialogue outcomes. Variation in chatbot design, specifically how the chatbot was presented to users, was found to impact user message brevity and dialogue style, and, by extension, response relevance and dialogue outcome. On the basis of the findings, we summarize lessons learnt and suggest directions for future research.
Probably Approximately Symmetric: Fast rigid Symmetry Detection with Global Guarantees
Creators: name: Korman, Simon
name: Litman, Roee
name: Avidan, Shai
name: Bronstein, Alex
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computational Geometry (cs.CG)
subject: FOS: Computer and information sciences
subject: I.3.5
subject: 65D18, 68U05

description: We present a fast algorithm for global rigid symmetry detection with approximation guarantees. The algorithm is guaranteed to find the best approximate symmetry of a given shape, to within a user-specified threshold, with very high probability. Our method uses a carefully designed sampling of the transformation space, where each transformation is efficiently evaluated using a sub-linear algorithm. We prove that the density of the sampling depends on the total variation of the shape, allowing us to derive formal bounds on the algorithm's complexity and approximation quality. We further investigate different volumetric shape representations (in the form of truncated distance transforms), and in such a way control the total variation of the shape and hence the sampling density and the runtime of the algorithm. A comprehensive set of experiments assesses the proposed method, including an evaluation on the eight categories of the COSEG data-set. This is the first large-scale evaluation of any symmetry detection technique that we are aware of.
Ultracold Chemistry and its Reaction Kinetics
Creators: name: Richter, Florian
name: Becker, Daniel
name: Bény, Cédric
name: Schulze, Torben A.
name: Ospelkaus, Silke
name: Osborne, Tobias J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We study the reaction kinetics of chemical processes occurring in the ultracold regime and systematically investigate their dynamics. Quantum entanglement is found to play a key role in driving an ultracold reaction towards a dynamical equilibrium. In case of multiple concurrent reactions Hamiltonian chaos dominates the phase space dynamics in the mean field approximation.
description: 15 pages, 5 figures
Bronchoscopic video synchronization for interactive multimodal inspection of bronchial lesions
Creators: name: Chang, Qi
name: Byrnes, Patrick D.
name: Ahmad, Danish
name: Toth, Jennifer
name: Bascom, Rebecca
name: Higgins, William E.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: With lung cancer being the most fatal cancer worldwide, it is important to detect the disease early. A potentially effective way of detecting early cancer lesions developing along the airway walls (epithelium) is bronchoscopy. To this end, developments in bronchoscopy offer three promising noninvasive modalities for imaging bronchial lesions: white-light bronchoscopy (WLB), autofluorescence bronchoscopy (AFB), and narrow-band imaging (NBI). While these modalities give complementary views of the airway epithelium, the physician must manually inspect each video stream produced by a given modality to locate the suspect cancer lesions. Unfortunately, no effort has been made to rectify this situation by providing efficient quantitative and visual tools for analyzing these video streams. This makes the lesion search process extremely time-consuming and error-prone, thereby making it impractical to utilize these rich data sources effectively. We propose a framework for synchronizing multiple bronchoscopic videos to enable an interactive multimodal analysis of bronchial lesions. Our methods first register the video streams to a reference 3D chest computed-tomography (CT) scan to produce multimodal linkages to the airway tree. Our methods then temporally correlate the videos to one another to enable synchronous visualization of the resulting multimodal data set. Pictorial and quantitative results illustrate the potential of the methods.
Ferroelectricity at ferroelectric domain walls
Creators: name: Wojdel, Jacek C.
name: Iniguez, Jorge
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present a first-principles study of model domain walls (DWs) in prototypic ferroelectric PbTiO3. At high temperature the DW structure is somewhat trivial, with atoms occupying high- symmetry positions. However, upon cooling the DW undergoes a symmetry-breaking transition characterized by a giant dielectric anomaly and the onset of a large and switchable polarization. Our results thus corroborate previous arguments for the occurrence of ferroic orders at structural DWs, providing a detailed atomistic picture of a temperature-driven DW-confined transformation. Beyond its relevance to the field of ferroelectrics, our results highlight the interest of these DWs in the broader areas of low-dimensional physics and phase transitions in strongly-fluctuating systems.
description: 10 pages with 6 figures embedded. Includes Suppl. Mats. More information at http://www.icmab.es/leem/jorge
Empathetic Robot Judge, we Trust You
Creators: name: Watamura, Eiichiro
name: Ioku, Tomohiro
name: Mukai, Tomoya
name: Yamamoto, Michio
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Information on the psychological mechanisms behind people’s perceptions of robot judges in the courtroom is limited. We aimed to determine whether perceptions of empathy increase people’s trust in robot judges and whether this trust influences people’s evaluation of judgments by a robot judge and their acceptance of such judges in the courtroom. We conducted a web-based randomized experiment on December 27, 2022 with 738 Japanese participants aged 18 years or older. Participants viewed one of four short clips and completed a questionnaire. Data from 531 individuals were included in the analysis. Results showed that perception of the judge’s empathy increased trust in that judge and impacted the judgment evaluation. Overall, participants perceived the human judge as significantly more empathetic than the robot judge. A perception of empathy from the robot judge was associated with a higher rate of accepting a robot judge in the courtroom via trust in that judge.
Random walk questions for linear quantum groups
Creators: name: Banica, Teodor
name: Bichon, Julien
Publisher: name: arXiv
Year: 2014
Subjects: subject: Operator Algebras (math.OA)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics

description: We study the discrete quantum groups $Γ$ whose group algebra has an inner faithful representation of type $π:C^*(Γ)\to M_K(\mathbb C)$. Such a representation can be thought of as coming from an embedding $Γ\subset U_K$. Our main result, concerning a certain class of examples of such quantum groups, is an asymptotic convergence theorem for the random walk on $Γ$. The proof uses various algebraic and probabilistic techniques.
description: 27 pages
Additional file 1 of Blocking of Transient Receptor Potential Vanilloid 1 (TRPV1) promotes terminal mitophagy in multiple myeloma, disturbing calcium homeostasis and targeting ubiquitin pathway and bortezomib-induced unfolded protein response
Creators: name: Beider, Katia
name: Rosenberg, Evgenia
name: Dimenshtein-Voevoda, Valeria
name: Sirovsky, Yaarit
name: Vladimirsky, Julia
name: Magen, Hila
name: Ostrovsky, Olga
name: Shimoni, Avichai
name: Bromberg, Zohar
name: Weiss, Lola
name: Peled, Amnon
name: Nagler, Arnon
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Supplementary Methods and Results.
title: Brief communication
title: Future avenues for permafrost science from the perspective of early career researchers
titleType: Subtitle
Creators: name: Fritz, Michael
name: Deshpande, B. N.
name: Bouchard, F.
name: Högström, E.
name: Malenfant-Lepage, J.
name: Morgenstern, A.
name: Nieuwendam, A.
name: Oliva, M.
name: Paquette, M.
name: Rudy, A. C. A.
name: Siewert, M. B.
name: Sjöberg, Y.
name: Weege, Stefanie
Publisher: name: Universität Potsdam
Year: 2019

description: Accelerating climate change and increased economic and environmental interests in permafrost-affected regions have resulted in an acute need for more directed permafrost research. In June 2014, 88 early career researchers convened to identify future priorities for permafrost research. This multidisciplinary forum concluded that five research topics deserve greatest attention: permafrost landscape dynamics, permafrost thermal modeling, integration of traditional knowledge, spatial distribution of ground ice, and engineering issues. These topics underline the need for integrated research across a spectrum of permafrost-related domains and constitute a contribution to the Third International Conference on Arctic Research Planning (ICARP III).
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 490
Predicting Galaxy Star Formation Rates via the Co-evolution of Galaxies and Halos
Creators: name: Watson, Douglas F.
name: Hearin, Andrew P.
name: Berlind, Andreas A.
name: Becker, Matthew R.
name: Behroozi, Peter S.
name: Skibba, Ramin A.
name: Reyes, Reinabelle
name: Zentner, Andrew R.
name: Bosch, Frank C. van den
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this paper, we test the age matching hypothesis that the star formation rate (SFR) of a galaxy of fixed stellar mass is determined by its dark matter halo formation history, and as such, that more quiescent galaxies reside in older halos. This simple model has been remarkably successful at predicting color-based galaxy statistics at low redshift as measured in the Sloan Digital Sky Survey (SDSS). To further test this method with observations, we present new SDSS measurements of the galaxy two-point correlation function and galaxy-galaxy lensing as a function of stellar mass and SFR, separated into quenched and star-forming galaxy samples. We find that our age matching model is in excellent agreement with these new measurements. We also employ a galaxy group finder and show that our model is able to predict: (1) the relative SFRs of central and satellite galaxies, (2) the SFR-dependence of the radial distribution of satellite galaxy populations within galaxy groups, rich groups, and clusters and their surrounding larger scale environments, and (3) the interesting feature that the satellite quenched fraction as a function of projected radial distance from the central galaxy exhibits an ~ r^-.15 slope, independent of environment. The accurate prediction for the spatial distribution of satellites is intriguing given the fact that we do not explicitly model satellite-specific processes after infall, and that in our model the virial radius does not mark a special transition region in the evolution of a satellite, contrary to most galaxy evolution models. The success of the model suggests that present-day galaxy SFR is strongly correlated with halo mass assembly history.
description: 14 pages, 6 figures, and one Appendix of tabulated data of new SFR-dependent galaxy clustering and galaxy-galaxy lensing measurements from SDSS. Accepted to MNRAS
Amphiphilic Nanogels as Versatile Stabilizers for Pickering Emulsions
Creators: name: Cui, Ruiguang
name: Ickler, Maret
name: Markovina, Ante
name: Kanwal, Sidra
name: Vogel, Nicolas
name: Klinger, Daniel
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: nano/microgels
subject: pickering emulsions
subject: phase inversion
subject: Flory−Huggins parameter
subject: interfacial tension
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Pickering emulsions (PEs) are stabilized by particles at the water/oil interface and exhibit superior long-term stability compared to emulsions with molecular surfactants. Among colloidal stabilizers, nano/microgels facilitate emulsification and can introduce stimuli responsiveness. While increasing their hydrophobicity is connected to phase inversion from oil-in-water (O/W) to water-in-oil (W/O) emulsions, a predictive model to relate this phase inversion to the molecular structure of the nano/microgel network remains missing. Addressing this challenge, we developed a library of amphiphilic nanogels (ANGs) that enable adjusting their hydrophobicity while maintaining similar colloidal structures. This enabled us to systematically investigate the influence of network hydrophobicity on emulsion stabilization. We found that W/O emulsions are preferred with increasing ANG hydrophobicity, oil polarity, and oil/water ratio. For nonpolar oils, increasing emulsification temperature enabled the formation of W/O PEs that are metastable at room temperature. We connected this behavior to interfacial ANG adsorption kinetics and quantified ANG deformation and swelling in both phases via atomic force microscopy. Importantly, we developed a quantitative method to predict phase inversion by the difference in Flory–Huggins parameters between ANGs with water and oil (χwater – χoil). Overall, this study provides crucial structure–property relations to assist the design of nano/microgels for advanced PEs.
Proton and neutron electromagnetic form factors from lattice QCD
Creators: name: Alexandrou, C.
name: Bacchio, S.
name: Constantinou, M.
name: Finkenrath, J.
name: Hadjiyiannakou, K.
name: Jansen, Karl
name: Koutsou, G.
name: Casco, A. Vaquero Aviles
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2018
Subjects: n: form factor
p: form factor: electromagnetic
form factor: electromagnetic
quark: mass dependence
quantum chromodynamics
quark: mass: twist
quark: flavor: 2
quark: flavor: 4
lattice field theory
numerical calculations
charge radius
magnetic moment
ground state
excited state
momentum dependence
isoscalar
isovector
finite size: effect

description: The electromagnetic form factors of the proton and the neutron are computed within lattice QCD using simulations of maximally twisted mass fermions with masses fixed to their physical values. We analyse two new ensembles of $N_f=2$ and $N_f=2+1+1$ and use several values of the sink-source time separation in the range of 1.0 fm to 1.6 fm to ensure ground state identification. The light quark disconnected contributions are evaluated to very high accuracy enabling us to include them in the determination of the proton and neutron form factors, the electric and magnetic radii, and the magnetic moments. We find that disconnected contributions are non-negligible and contribute up to 15% for the case of the neutron electric charge radius.
PILOT: equivariant diffusion for pocket-conditioned de novo ligand generation with multi-objective guidance via importance sampling
Creators: name: Cremer, Julian
name: Le, Tuan
name: Noé, Frank
name: Clevert, Djork-Arné
name: Schütt, Kristof T.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: generation of ligands
subject: protein pocket
subject: equivariant diffusion
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: The generation of ligands that both are tailored to a given protein pocket and exhibit a range of desired chemical properties is a major challenge in structure-based drug design. Here, we propose an in silico approach for the de novo generation of 3D ligand structures using the equivariant diffusion model PILOT, combining pocket conditioning with a large-scale pre-training and property guidance. Its multi-objective trajectory-based importance sampling strategy is designed to direct the model towards molecules that not only exhibit desired characteristics such as increased binding affinity for a given protein pocket but also maintains high synthetic accessibility. This ensures the practicality of sampled molecules, thus maximizing their potential for the drug discovery pipeline. PILOT significantly outperforms existing methods across various metrics on the common benchmark dataset CrossDocked2020. Moreover, we employ PILOT to generate novel ligands for unseen protein pockets from the Kinodata-3D dataset, which encompasses a substantial portion of the human kinome. The generated structures exhibit predicted IC50 values indicative of potent biological activity, which highlights the potential of PILOT as a powerful tool for structure-based drug design.
title: Impact of temperature and precipitation extremes on the flowering dates of four German wildlife shrub species
Creators: name: Siegmund, Jonatan Frederik
name: Wiedermann, Marc
name: Donges, Jonathan F.
name: Donner, Reik Volker
Publisher: name: Universität Potsdam
Year: 2019

description: Ongoing climate change is known to cause an increase in the frequency and amplitude of local temperature and precipitation extremes in many regions of the Earth. While gradual changes in the climatological conditions have already been shown to strongly influence plant flowering dates, the question arises if and how extremes specifically impact the timing of this important phenological phase. Studying this question calls for the application of statistical methods that are tailored to the specific properties of event time series. Here, we employ event coincidence analysis, a novel statistical tool that allows assessing whether or not two types of events exhibit similar sequences of occurrences in order to systematically quantify simultaneities between meteorological extremes and the timing of the flowering of four shrub species across Germany. Our study confirms previous findings of experimental studies by highlighting the impact of early spring temperatures on the flowering of the investigated plants. However, previous studies solely based on correlation analysis do not allow deriving explicit estimates of the strength of such interdependencies without further assumptions, a gap that is closed by our analysis. In addition to direct impacts of extremely warm and cold spring temperatures, our analysis reveals statistically significant indications of an influence of temperature extremes in the autumn preceding the flowering.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 497
In-Process Laser Scanning Technology for Micro Assembly
Creators: name: Rathmann, Sven
name: Raatz, Annika
name: Schöttler, Kerstin
name: Hesselbach, Jürgen
Publisher: name: Bedford : Euspen (European Society for Precision Engineering and Nanotechnology)
Year: 2007
Subjects: subject: Konferenzschrift
subject: Feinwerktechnik
subject: Mikrosystemtechnik
subject: Nanotechnologie
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: To recognize edges of components in an assembly process, in particular of microelectronic or micro system components, nowadays vision systems are preferred. These systems are working fast but the results strongly depend on ambient conditions. In most sensor guided assembly systems laser displacement sensors are implemented additionally to vision systems. These sensors are used for detection of the components height. In this paper a scanning method is presented that detects edges by using a laser displacement sensor. These data can be used by robot assembly system for a sensor guided assembly process. Further by this technique is extended in order to gain 3D-infonnation of micro components and a proposal of the field of application is outlined.
Influences on the Automated Assembly of Hybrid Microsystems with High Accuracy
Creators: name: Hesselbach, Jürgen
name: Raatz, Annika
name: Schöttler, Kerstin
Publisher: name: Berlin [u.a.] : VDE-Verlag
Year: 2007
Subjects: subject: Konferenzschrift
subject: MEMS
subject: Mikrosystemtechnik
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: Nowadays, an ongoing trend of miniaturization of products and components can be observed in nearly all application areas in the world. As for microsystems, a distinction is drawn between monolithic and hybrid microsystems. The latter group requires some kind of assembly process. For the assembly of hybrid microsystems, a high assembly accuracy in the range of a few micrometers is required. In order to reach this accuracy, an assembly system for sensor guided microassembly has been developed at the Collaborative Research Centre 516 “Design and manufacturing of active micro systems”. This paper describes the design of a system for automated assembly of hybrid microsystems. The influences on the accuracy will be analyzed on the basis of an example for an automated assembly process.
Adapting the geological maps to allow a better experience in the Hiking paths in aspiring Geopark Algarvensis Loulé-Silves-Albufeira
Creators: name: Rodrigues, Bruno
name: Veiga-Pires, Cristina
name: Teixeira, Paula
name: Oliveira, Sónia
Publisher: name: Zenodo
Year: 2021
Subjects: Hiking trails, geopark, story map

description: The aspiring Geopark Algarvensis Loulé-Silves-Albufeira to UNESCO World Geopark has a geological heritage of great importance at the national and international levels. In the area that encompasses the municipality of Silves, there are 6 walking routes in a total length of 80km. These were not planned to promote the geology however they allow the visitors to make a journey in the geological and landscape interpretation from the geologic record. The geological cartography available at a scale of 1:100 000 makes a detailed interpretation difficult. In this sense, a geological survey was carried out at a scale of 1:15 000 along each of the pedestrian paths. This geological survey and adaptation were made based on the existing one. This "update" of the geologic map allows the creation of a list of sites or places of geological interest. In the most important sites, a mark on the field with a QR code will be installed. Based on all the elements surveyed along the hiking paths a story map is being created allowing a virtual tour of the geopark territory.
Additional file 1 of Neck subcutaneous nodule as first metastasis from broad ligament leiomyosarcoma: a case report and review of literature
Creators: name: Cazzato, Fiorella
name: D’Ercole, Angela
name: Luca, Graziano De
name: Aiello, Francesca B.
name: Croce, Adelchi
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer

description: Additional file 1: Timeline care.
Additional file 1 of Material characterisation of a painted beehive panel by advanced spectroscopic and chromatographic techniques in combination with hyperspectral imaging
Creators: name: Retko, Klara
name: Maša Kavčič
name: Legan, Lea
name: Ropret, Polonca
name: Škafar, Bojana Rogelj
name: Yingwang Gao
name: Gilchrist, John
name: Strlič, Matija
name: Cigić, Irena Kralj
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 1. Raman and infrared spectroscopy experimental data.
Additional file 1 of Assessing cardiovascular disease risk factor screening inequalities in India using Lot Quality Assurance Sampling
Creators: name: Nambiar, Devaki
name: Soumyadeep Bhaumik
name: Pal, Anita
name: Rajani Ved
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1.
Greifsysteme für das Fügen mit schmelzklebstoff-vorbeschichteten Bauteilen zur Fertigung von MEMS und MOEMS
Creators: name: Rathmann, Sven
name: Raatz, Annika
name: Dietrich, Franz
name: Hemken, Gregor
name: Böhm, Stefan
Publisher: name: Berlin [u.a.] : VDE-Verlag
Year: 2007
Subjects: subject: Konferenzschrift
subject: Mikrosystemtechnik
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: Bei der Fertigung dreidimensionaler (MEMS/MOEMS)-Strukturen durch hybride Integration von Einzelbauelementen zu einem Gesamtsystem werden aus prozesstechnischen und wirtschaftlichen Gründen in der Regel batchfähige Prozesse verwendet. Als wichtige Aufbau- und Verbindungstechnik hat sich dabei das Kleben etabliert. Im Rahmen des Sonderforschungsbereichs 516 wurde eine batchfähige Verbindungstechnik auf Basis von Schmelzklebstoffen entwickelt. Sie ermöglicht, Mikrobauteile vorzubeschichten und in einem anschließenden Fügeprozess diese Bauteile zu montieren. Dabei können auf Grund sehr schneller Abbindezeiten von Schmelzklebstoffen kurze Fügeprozesszeiten erreicht werden. Dieser Beitrag stellt Greifsysteme vor, mit denen mit Schmelzklebstoff vorbeschichtete Bauteile gefügt werden können. Dabei hängt die Wahl des einzusetzenden Greifsystems von der Prozessführung, der Wärmeführung sowie von den thermischen Eigenschaften des zu fügenden Bauteils ab.
The Triassic Vertebrates Of The Aspiring Geopark Algarvensis
Creators: name: Campos, Hugo
Publisher: name: Zenodo
Year: 2021
Subjects: Algarve, Geopark, Triassic, Metoposaurus, placodonts, Portugal

description: The paleontological research conducted during the last decade at the territory of Geopark Algarvensis, in Southern Portugal, has revealed the occurrence of rich fossil vertebrate bearing layers, in the Triassic of the Grés de Silves Formation. One of the most notable discoveries is the bonebed composed of numerous remains of temnospondyl amphibian Metoposaurus algarvensis, a species known exclusively from the Geopark Algarvensis territory. The remaining recovered fauna includes the mandible of the first record of phytosaurs in the Iberian Peninsula and remains of the first placodonts reported in Portugal. While M. algarvensis and phytosaur remains were uncovered solely in one fossiliferous bed in the Penina site (Loulé municipality), the placodont remains are quite abundant occurring at multiple stratigraphic levels and localities spread throughout the Geopark territory. Based on the cranial and osteoderm material, an henodontid placodont has been identified. Due to the rarity of the fossil record of Henodontidae, known only from two other sites worldwide, the Algarve record is of exceptional scientific importance. The mentioned findings were instrumental in propelling the conception of the Geopark Algarvensis project, for their national and international relevance. The Triassic vertebrates have not only been a subject of scientific studies but also became a central topic of museological exhibitions, educational activities, merchandise and pieces of art, fostering a sense of identity within the local communities and serving as ambassadors of paleontology and geology in the aspiring Geopark Algarvensis.
title: Open-source modular solutions for flexural isostasy
title: gFlex v1.0
titleType: Subtitle
Creators: name: Wickert, Andrew D.
Publisher: name: Universität Potsdam
Year: 2019

description: Isostasy is one of the oldest and most widely applied concepts in the geosciences, but the geoscientific community lacks a coherent, easy-to-use tool to simulate flexure of a realistic (i.e., laterally heterogeneous) lithosphere under an arbitrary set of surface loads. Such a model is needed for studies of mountain building, sedimentary basin formation, glaciation, sea-level change, and other tectonic, geodynamic, and surface processes. Here I present gFlex (for GNU flexure), an open-source model that can produce analytical and finite difference solutions for lithospheric flexure in one (profile) and two (map view) dimensions. To simulate the flexural isostatic response to an imposed load, it can be used by itself or within GRASS GIS for better integration with field data. gFlex is also a component with the Community Surface Dynamics Modeling System (CSDMS) and Landlab modeling frameworks for coupling with a wide range of Earth-surface-related models, and can be coupled to additional models within Python scripts. As an example of this in-script coupling, I simulate the effects of spatially variable lithospheric thickness on a modeled Iceland ice cap. Finite difference solutions in gFlex can use any of five types of boundary conditions: 0-displacement, 0-slope (i.e., clamped); 0-slope, 0-shear; 0-moment, 0-shear (i.e., broken plate); mirror symmetry; and periodic. Typical calculations with gFlex require << 1 s to similar to 1 min on a personal laptop computer. These characteristics - multiple ways to run the model, multiple solution methods, multiple boundary conditions, and short compute time - make gFlex an effective tool for flexural isostatic modeling across the geosciences.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 498
Automated Assembly of Hybrid Microsystems
Creators: name: Schöttler, Kerstin
name: Rathmann, Sven
name: Raatz, Annika
name: Hesselbach, Jürgen
Publisher: name: Bedford : Euspen (European Society for Precision Engineering and Nanotechnology)
Year: 2007
Subjects: subject: Konferenzschrift
subject: Feinwerktechnik
subject: Mikrosystemtechnik
subject: Nanotechnologie
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: The paper describes the design of a system for the automated assembly of hybrid microsystems and the accuracies of the components. The influences on the accuracy will be analyzed on the basis of an example for an automated assembly process. While the object sizes reach centimeter range, they have to be assembled with an assembly accuracy of only a few micrometers. A relative positioning accuracy of 0.8 pm is reached in this process.
The nucleation and propagation of solitary Schallamach waves
Creators: name: Viswanathan, Koushik
name: Mahato, Anirban
name: Chandrasekar, Srinivasan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We isolate single Schallamach waves --- detachment fronts that mediate inhomogeneous sliding between an elastomer and a hard surface --- to study their creation and dynamics. Based on measurements of surface displacement using high-speed \emph{in situ} imaging, we establish a Burgers vector for the waves. The crystal dislocation analogues of nucleation stress, defect pinning and configurational force are demonstrated. It is shown that many experimentally observed features can be quantitatively described using a conventional model of a dislocation line in an elastic medium. We also highlight the evolution of nucleation features such as surface wrinkles, with consequences for interface delamination.
description: 24 pages, 9 figures
Investigation on the International State of the Art of Micro Production Technology
Creators: name: Hesselbach, J.
name: Raatz, A.
name: Wrege, J.
name: Herrmann, H.
name: Weule, H.
name: Fleischer, J.
name: Buchholz, C.
name: Tritschler, H.
name: Knoll, M.
name: Elsner, J.
name: Klocke, F.
name: Weck, M.
name: Von Bodenhausen, J.
name: Von Klitzing, A.
Publisher: name: Bedford : Euspen (European Society for Precision Engineering and Nanotechnology)
Year: 2003
Subjects: subject: Konferenzschrift
subject: Feinwerktechnik
subject: Mikrosystemtechnik
subject: Nanotechnologie
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: The study “microPRO” dealing with the international state of the art of micro production technology was conducted by the above named Institutes. The objective of this study was to determine the worldwide state-of-the-art technology and research in micro production technology by means of scientific investigations and technical discussions with the technology leaders and, based on this, to identify the required research and development as well as the future potentials of these technologies in view of the market-overlapping economic utilization of miniaturized products.
El amparo constitucional en Colombia como protección al buen nombre ante publicaciones en Internet
Creators: name: Ibañez Diaz, Sara Maria
Publisher: name: Facultad Derecho
Year: 2019
Subjects: subject: Recurso de amparo - Aspectos constitucionales - Colombia
subject: Internet - Aspectos constitucionales - Colombia
subject: Libertad de palabra - Aspectos sociales - Colombia
subject: Buen nombre
subject: Libertad de expresión
subject: Internet
subject: Libertad constitucional

description: La tesis aborda el conflicto entre el derecho al buen nombre y la libertad de expresión en el contexto digital, centrándose en la protección constitucional en Colombia. A medida que las tecnologías avanzan, las vulneraciones al buen nombre se amplifican en el entorno digital, debido a la rápida difusión y anonimato en Internet. La acción de tutela se ha utilizado como un mecanismo de protección, aunque a veces resulta ineficaz para mitigar los daños ocasionados. La tesis explora cómo la libertad da expresión, espacialmente en los medios de comunicación y redes sociales, está protegida constitucionalmente, pero debe equilibrarse con la protección del buen nombre. También se analiza la dificultad de rectificar el contenido una vez que ha sido publicado en línea, y cómo las opiniones expresadas por influenciadores online pueden vulnerar este derecho. A través de un análisis detallado de la jurisprudencia colombiana, la Investigación resalta la necesidad de adaptar las leyes a la era digital, y considera las limitaciones de los mecanismos legales actuales para la protección del buen nombra frente a In publicaciones en línea.
description: The thesis examines the conftict between the right to e good name and freedom of expression in the digital context, focusing on constitutional protection in Colombia. As technology advances, lnfringements on reputation are amplified in the digital environment due to the rapid disaemination and anonymity on the internet. The tutela action has been employed as a protection mechanism, although it is sometimes ineffective in mitigating the damage caused. The thesis explores how freedom of expression, particularly in the media and social networks, is constitutionally protected, but must be balanced with the protection of one's good name. lt also addresses the difficulty of rectitying content once published online and how opinions expressed by online influencers can infringe upon this right. Through a detalled analysis of Colomblan jurisprudence, the research highilghts the need to adapt lawa to the digital age and considers the limitations of current legal mechanisms in protecting reputation against online publications.