cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Process Evaluation of the Integrated Childsmile Programme. Report of the first tranche of fieldwork (August 2010 to June 2011)
Creators: name: Eaves, Jennifer
name: Williams, Nicola
name: Deas, Leigh
name: Mattu, Leanne
name: Robertson, Lynn
name: Larsen, Helle Buch
name: Gnich, Wendy
Publisher: name: figshare
Year: 2017
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine

description: This report provides findings from the first tranche of the process evaluation of the integrated Childsmile programme, covering the period August 2010 to June 2011.
Childsmile is the national, early years oral health improvement in Scotland. It comprises interacting components (Core: toothbrushing in all nurseries and targeted primary schools, provision of oral health packs at key stages; Nursery & School: fluoride varnishing provided to children in targeted educational establishments; and Practice: support for families with young children to register with and attend dental practices and to engage in protecting their children's oral health).
The purpose of the process evaluation is to explore implementation of the programme, to aid the interpretation of its outcomes.
title: Supporting patient-centered decision-making through a patient decision aid that incorporates individual patient risks, preferences and quantitative benefit-harm assessment
Creators: name: Menges, Dominik
name: Aschmann, Hélène E.
name: Puhan, Milo A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: Patient-centered decision-making in preventive medicine involves the consideration of an individual's baseline risks for disease, expected treatment effects and outcomes, and personal preferences. Whether a treatment ultimately provides a net benefit strongly [for full text, please go to the a.m. URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Supplementary Material for: Novel de novo AVPR2 Variant in a Patient with Congenital Nephrogenic Diabetes Insipidus
Creators: name: Joshi, S.
name: Brandstrom, P.
name: Gregersen, N.
name: Rittig, S.
name: Christensen, J.H.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Early diagnosis and treatment of congenital nephrogenic diabetes insipidus (CNDI) are essential due to the risk of intellectual disability caused by repeated episodes of dehydration and rapid rehydration. Timely genetic testing for disease-causing variants in the arginine vasopressin receptor 2 (AVPR2) gene is possible in at-risk newborns with a known family history of X-linked CNDI. In this study, a Swedish male with no family history was diagnosed with CNDI at 6 months of age during an episode of gastroenteritis. We analyzed the coding regions of AVPR2 by PCR and direct DNA sequencing and identified an 80-bp duplication in exon 2 (GenBank NM_000054.4; c.800_879dup) in the proband. This variant leads to a frameshift and introduces a stop codon four codons downstream (p.Ala294Profs*4). The variant gene product either succumbs to nonsense-mediated decay or is translated to a truncated nonfunctional vasopressin V2 receptor. This variant was absent in four unaffected family members, including his parents, as well as in 100 alleles from healthy controls, and is thus considered a novel de novo disease-causing variant. Identification of the disease-causing variant facilitated precise diagnosis of CNDI in the proband. Furthermore, it allows future genetic counseling in the family. This case study highlights the importance of genetic testing in sporadic infant cases with CNDI that can occur due to de novo variants in AVPR2 or several generations of female transmission of the disease-causing variant.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Cart. 190 (11 H 75), 316 folios, f. 0154v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0154v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0154v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Supplementary Material for: Lymphopenia and CD4+/CD8+ Cell Reduction under Fumaric Acid Esters
Creators: name: Sondermann, W.
name: Rompoti, N.
name: Leister, L.
name: Huptas, L.
name: Klode, J.
name: Dissemond, J.
name: Körber, A.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: Fumaric acid esters (FAEs) are a broadly used therapy option for patients suffering from moderate-to-severe plaque psoriasis. Various studies in psoriasis have already shown peripheral blood lymphopenia during oral FAE therapy. Smaller studies also documented a reduction of CD4+ and CD8+ cell counts. Up to now, there are few case reports on opportunistic infections under FAE therapy - all of them associated with lymphopenia. Objective: To examine the influence of FAEs on white blood cells with special regard to leukocytes, lymphocytes, and CD4+ and CD8+ cells during psoriasis therapy. Patients and Methods: A cohort of 105 patients with diagnosed moderate-to-severe chronic plaque psoriasis was enrolled in this single-centre observational trial. For a cohort of 36 patients, T-cell subset analyses were performed. Results: Of the total, 65 patients were male (61.9%) and 40 (38.1%) female; the mean age was 43.3 years (range 16-73 years). The median lymphocyte count was significantly reduced by about 35.8% after the first 6 months of therapy. When assessing the lymphocyte count nadir over the whole period observed, 46.7% of the patients developed lymphopenia. Severe lymphopenia (<500/µL) was documented in 11.4% of the patients. The CD4+ and CD8+ cell counts were significantly reduced by about 30.2 and 45.3%, respectively. Conclusion: To the best of our knowledge this is the largest clinical investigation analysing prospectively CD4+ and CD8+ cell counts in psoriasis patients receiving FAEs. We suggest periodic monitoring of absolute lymphocyte counts as well as the establishment of the determination of T-cell subsets prior to and during therapy.
title: Klinisch-ethische Einzelfallberatung bei erwachsenen Menschen – ein Cochrane Review
Creators: name: Nadolny, Stephan
name: Schildmann, Jan
name: Haltaufderheide, Joschka
name: Gysels, Marjolein
name: Vollmann, Jochen
name: Bausewein, Claudia
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Die Ethikfallberatung ist eine Intervention zur Unterstützung bei ethisch schwierigen Entscheidungssituationen im Gesundheitswesen. Die Wirksamkeit sowie die Auswahl adäquater Outcomes zum Wirksamkeitsnachweis werden kritisch diskutiert. Ziel der systematischen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Clinical Coder Working Group Update
Creators: name: Shepheard, Jennie
name: Robinson, Kerin
name: Muratore, Catherine
name: Ramsden, Lisette
name: Robey, Christopher
name: Torney, Belinda
name: Jordan, Cassandra
name: Williams, Lyn
name: Richardson, Sally
name: Gjorgioski, Stephanie
name: Holroyd, Brooke
name: Njeru, Jodee
name: Turnell, Melissa
name: Hayes, Isabel
name: Wilton, Kathy
name: Nicola, Hunt
name: Francis, Simone
Publisher: name: La Trobe
Year: 2023

description: No description supplied
New fossil leaves and fruits of Lauraceae from the Middle Miocene of Fujian, southeastern China differentiated using a cluster analysis
Creators: name: Zixi Wang
name: Fankai Sun
name: Jidong Wang
name: Defei Yan
name: Junling Dong
name: Mingxuan Sun
name: Bainian Sun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: The fossil record of Lauraceae can be traced back to the Early Cretaceous of eastern Asia based on fossil flowers. Here, we refer a number of new occurrences of leaf and fruit fossils of Lauraceae from the Middle Miocene of Zhangpu, Fujian, China, to seven species. These data provide evidence supporting the fact that a diverse subtropical, or tropical, Lauraceae-dominated evergreen forest surrounded this region 15 million years ago (Mya). The Lauraceae fossils presented in this paper provide evidence for the evolution of this group as well as new materials that enable the study of the Fujian Province Neogene flora. The fossils described in this paper fill in the gaps in studies about Lauraceae pollen in the Middle Miocene from Fotan, Fujian, China. In addition, these fossils also enrich the Middle Miocene fossil records of Lauraceae in eastern Asia, especially improving the study of the macrostructures and reproductive organs of fossil Lauraceae from southern China. The similarity between fossil and modern fruits shows that during the Middle Miocene the fruit morphological of Lauraceae have changed very little. We also identify families where the fossils we report belong to their closest relatives and can be used to reconstruct the paleoenvironment of Fujian in the Middle Miocene.
title: Ja immer, kommt darauf an, oder nie? Früherkennung von Prostatakrebs mittels PSA-Test – Befragung von Hausärzten und Urologen im Nordwesten
Creators: name: Freitag, Michael Hermann
name: Kappen, Sanny
name: Jürgens, Verena
name: Winter, Alexander
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Zum PSA-Test existieren weiterhin unterschiedliche Auffassungen und Einstellungen. Die deutsche S3-Leitlinie Prostatakarzinom beinhaltet ein Sondervotum der DEGAM, welches Hausärzten in Anbetracht der nicht eindeutigen Evidenzlage keine aktive Patientenansprache bzgl. der PSA-Testung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Supplementary Material for: Is There a Relation between Vitamin D and Interleukin-17 in Vitiligo? A Cross-Sectional Study
Creators: name: Aly, D.
name: Mohammed, F.
name: Sayed, K.
name: Gawdat, H.
name: Mashaly, H.
name: Abdel Hay, R.
name: Elias, T.
name: Agaiby, M.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: High interleukin (IL)-17 contributes to vitiligo pathogenesis. Vitamin D has been assessed in vitiligo, with no reports targeting its relation to IL-17. Objective: To evaluate a possible regulatory effect of vitamin D on IL-17 and their relation to disease activity in vitiligo. Methods: This study included 30 vitiligo patients and 40 controls evaluated for IL-17 and vitamin D serum levels by ELISA technique. Results: IL-17 was significantly higher (p = 0.001) whereas vitamin D was found to be lower among the patients (p < 0.001). Multivariable regression was performed to evaluate the relationship between IL-17 and vitamin D levels with the demographic data on the patients, revealing a nonsignificant relationship (p > 0.05). A significant positive correlation was noted between vitamin D levels and disease duration. Conclusion: Vitamin D represents a potential player in the pathogenesis of vitiligo. Its possible regulatory relation to IL-17, together with its weight as a screening tool in vitiligo, needs further evaluation.
title: Nutzen und Schäden nichtinvasiver Pränataltests – Entwicklung einer Harding-Zentrum-Faktenbox zur Unterstützung einer informierten Entscheidung werdender Mütter
Creators: name: Beckhaus, Julia
name: Wilhelm, Christoph
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Die Entscheidung zur Durchführung des nichtinvasiven Pränataltests (NIPT) basiert auf einer individuellen Beurteilung von Nutzen und Schäden, über die informiert werden muss. Einfache Werkzeuge, um eine informierte Entscheidung zu ermöglichen,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: ADCO, Ordre cistercien : comptes (1499-1515) (11 H 1162), f. 00251
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162), f. 00251, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
title: Kinesiotape treatment for postoperative edema after knee surgery – Using a systematic review to inform the design of a randomized controlled pragmatic trial
Creators: name: Hoermann, Julie
name: Vach, Werner
name: Saxer, Franziska
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: Postoperative edema, e.g. after knee surgery, negatively impacts wound healing, mobility and patients’ wellbeing. Decongestive measures consist of manual lymphatic drainage and compression (MLD), though kinesiotaping gains popularity. The technique has been [for full text, please go to the a.m. URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Relevante Veränderungen: Wie bekommen wir die MID, die wir brauchen?
Creators: name: Morche, Johannes
name: Sixtensson, Madlen
name: Conrad, Susann
name: Kaiser, Laura
name: Mejda, Michael
name: Jung, Britta
name: Kulig, Michael
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Die Abteilung Fachberatung Medizin der Geschäftsstelle des Gemeinsamen Bundesausschusses (G-BA) berät die Gremien des G-BA zu methodischen Fragestellungen, u.a. im Bereich der Nutzenbewertung von Arzneimitteln für seltene Leiden (Orphan Drugs) und in der[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Erprobung von Innovationen im Gemeinsamen Bundesausschuss – am Puls der Zeit?
Creators: name: Wolf, Katrin
name: Fröhlich, Matthias
name: Riese, Brigitte
name: Dettloff, Matthias
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Seit einiger Zeit hat der Gemeinsame Bundesausschuss (G-BA) in Deutschland die Möglichkeit Studien zu Untersuchungs- und Behandlungsmethoden (und ggf. jeweils relevanten Medizinprodukten) aufgrund eigener Beratungen oder nach Herstelleranträgen zu initiieren[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Induction of plant disease resistance upon treatment with yeast cell wall extract
Creators: name: Takaomi Yaguchi
name: Kinami, Tomohisa
name: Ishida, Tetsuya
name: Takaomi Yasuhara
name: Takahashi, Kosaku
name: Matsuura, Hideyuki
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: It has been reported that treatment with yeast cell wall extract (YCWE) induces PDF1 and PR-1 gene expression; these transcripts are important markers of plant disease resistance, though the detailed signaling mechanisms that induce these defense responses are still unknown. In this report, we found that YCWE treatment triggered rice cell suspension cultures to accumulate phenylalanine (Phe), cis-12-oxo-phytodienoic acid (OPDA), 12-hydroxyjasmonoyle isoleucine (12OHJA-Ile), and azelaic acid (AzA). YCWE treatment also reduced endogenous triacylglycerol (TG) content. The addition of 13C-uniform-labeled oleic, linoleic and linolenic acids to the rice cell suspension cultures gave rise to 13C-uniform-labeled AzA. It was also found that YCWE treatment for Arabidopsis thaliana resulted in accumulations of OPDA, AzA, Phe, and camalexin together with enhanced resistance against Botrytis cinerea infection. This suggested that YCWE treatment upon plants may activate JA and AzA signaling systems to induce plant disease resistance. Yeast cell wall extract (YCWE) treatment induces plant defense response.
title: ADCO, Second cartulaire de Saint-Étienne de Dijon (XVe siècle), Cart. 22 (G 126), 110 folios, f. 0049
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Second cartulaire de Saint-Étienne de Dijon (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 22 (G 126), 110 folios, f. 0049, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Second cartulaire de Saint-Étienne de Dijon (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 22 (G 126), 110 folios, f. 0049, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
title: Disagreement between non-randomized real-world evidence and randomized trials: a meta-epidemiological study on disagreement and potential causes for disagreement
Creators: name: Mathes, Tim
name: Rombey, Tanja
name: Pieper, Dawid
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: Meta-epidemiological studies comparing effects from randomized controlled trials (RCT) and non-randomized studies (NRS) have shown heterogeneous results. Many publications theoretically discuss possible causes for differences in effect estimates from RCT and NRS performed[for full text, please go to the a.m. URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages
Creators: name: Morrow, Riley
name: Allam, Amr
name: Konecnik, J
name: Baloyan, D
name: Dijkstra, C
name: Eissmann, Moritz
name: Jacob, Simon
name: O'Brien, Megan
name: Poh, Ashleigh
name: Ernst, Matthias
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 320499
subject: Immunology not elsewhere classified
classificationCode: 321199
subject: Oncology and carcinogenesis not elsewhere classified

description: Aberrant expression of the oncoprotein c-Myc (Myc) is frequently observed in solid tumors and is associated with reduced overall survival. In addition to well-recognized cancer cell-intrinsic roles of Myc, studies have also suggested tumor-promoting roles for Myc in cells of the tumor microenvironment, including macrophages and other myeloid cells. Here, we benchmark Myc inactivation in tumor cells against the contribution of its expression in myeloid cells of murine hosts that harbor endogenous or allograft tumors. Surprisingly, we observe that LysMCre-mediated Myc ablation in host macrophages does not attenuate tumor growth regardless of immunogenicity, the cellular origin of the tumor, the site it develops, or the stage along the tumor progression cascade. Likewise, we find no evidence for Myc ablation to revert or antagonize the polarization of alternatively activated immunosuppressive macrophages. Thus, we surmise that systemic targeting of Myc activity may confer therapeutic benefits primarily through limiting Myc activity in tumor cells rather than reinvigorating the anti-tumor activity of macrophages.
title: Anforderungen zur Berücksichtigung der Variable „Geschlecht“ / „Gender“ im Forschungsprozess in Antragsrichtlinien von Förderinstitutionen im Gesundheitswesen
Creators: name: Aldin, Angela
name: Clever, Katharina
name: Skoetz, Nicole
name: Meyer, Gabriele
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Einige Institutionen der Forschungsförderung im Gesundheitswesen erwarten die Berücksichtigung von Geschlechteraspekten in Forschungsanträgen. Ziel der vorliegenden Untersuchung ist es daher zu erfassen, welche spezifischen Anforderungen Förderinstitutionen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Philosophie und Literatur bei Cicero
Creators: name: Vielberg, Meinolf
Publisher: name: Trier University
Year: 2022

description: This paper explores the relationship between philosophy and literature in the dialogues of Cicero. It argues that Cicero was a sceptic Roman philosopher who used the freedom permitted by his epistemological point of view to systematically present the doctrines of all the Hellenistic schools of thought without open polemics in an almost neutral and rather new way. In presenting the doctrines of the different Hellenistic schools of thought, Cicero, on the one hand, devaluates only the philosophy of Epicurus by means of rhetoric. On the other hand, he allows his reader, and even stimulates him, to make a rational choice between different philosophical options such as either the ethics of Stoicism or of the Peripatetic school. To this end, Cicero depicts his fellow citizens and himself in the situation or process of theoretical (and practical) decision-making between different philosophical points of view or even different ways of life.
Desertification, crop yield and economic development: a disaggregated analysis
Creators: name: Malpede, Maurizio
name: Percoco, Marco
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: This study uses a global grid-level dataset, integrating gross domestic product (GDP) per capita with crop yield and climate variables to examine the economic impact of climate-induced desertification. We use the aridity index (AI) to measure desertification and find that annual variations of soil aridity have a more significant economic impact than precipitation and temperature when taken alone, with Africa experiencing the most significant effect. We identify the reduced agricultural yield as a potential channel behind the desertification-economic growth nexus. Finally, projections suggest that by 2040, desertification could reduce GDP per capita in sub-Saharan Africa by up to 10%. These findings underscore the need for policies to mitigate the economic impacts of climate-induced desertification in vulnerable regions, contributing to the broader understanding of how climatic conditions affect economic development.
title: Welche Evidenz beschreibt die benötigte Evidenz – Erfahrungen aus einer Cluster-randomisierten Interventionsstudie zu Patienten-zentrierter Kommunikation
Creators: name: Burggraf, Larissa
name: Stark, Stefanie
name: Kluge, Marie
name: Roos, Marco
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Patienten-zentrierte Kommunikation (PCC) gilt in der Forschung als erstrebenswert. PCC will dabei Ärzte und Patienten in einem gemeinsamen evidenz-orientierten Handeln unterstützen. Schulungsinterventionen sollen Ärzte in die Lage versetzen, patienten-zentriert[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Determination of ewe behaviour around lambing time and prediction of parturition 7 days prior to lambing by tri-axial accelerometer sensors in an extensive farming system
Creators: name: Sohi, Rajneet
name: Almasi, Fazel
name: Nguyen, Hien
name: Carroll, Alexandra
name: Trompf, Jason
name: Weerasinghe, Maneka
name: Bervan, Aidin
name: Godoy, Boris
name: Ahmed, Awais
name: Stear, Michael
name: Desai, Aniruddha
name: Jois, Markandeya
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 300399
subject: Animal production not elsewhere classified
classificationCode: 310999
subject: Zoology not elsewhere classified

description: Context: Lamb loss and dyctocia are two major challenges in extensive farming systems. While visual observation can be impractical due to the large sizes of paddocks, number of animals and high labour cost, wearable sensors can be used to monitor the behaviour of ewes as there might be changes in their activities prior to lambing. This provides sufficient time for the farm manager to nurse those ewes that are at risk of dyctocia. Aim: The objective of this study was to determine whether the behaviour of a pregnant ewe could predict the time of parturition. Methods: Two separate trials were conducted: the first trial (T1), with 32 ewes, included human/video observations, and the second trial (T2), with 165 ewes, conducted with no humans present, to emulate real extensive farming settings. The ewes were fitted with tri-axial accelerometer sensors by means of halters. Three-dimensional movement data were collected for a period of at least 7 and 14 days in T1 and T2 respectively. The sensor units were retrieved, and their data downloaded using ActiGraph software. Ewe behaviour was determined through support vector machine learning (SVM) algorithm, including licking, grazing, rumination, walking, and idling. The behaviours of ewes predicted by analysis of sensor data were compared with behaviours determined using visual observation (video recordings), with time synchronisation to validate the results. Deep learning and neural-network algorithms were used to predict lambing time. Key results: The concordance percentages between visual observation and sensor data were 90 ± 11, 81 ± 15, 95 ± 10, 96 ± 6, and 93 ± 8% ± s.d. for grazing, licking, rumination, idling, and walking respectively. The deep-learning model predicted the time of lambing with 90% confidence via a quantile regression method, which can be interpereted as 90% prediction intervals, and shows that the time of lambing can be predicted with reasonable confidence approximately 240 h before the actual lambing events. Conclusion: It was possible to predict the time of parturition up to 10 days before lambing. Implications: The behaviour of ewes around lambing time has a direct effect on the survival of the lambs and therefore plays an important part in animal management. This knowledge could improve the productivity of sheep and considerably decrease lamb mortality rates.
title: Design, Analysis and Reporting of Multi-Arm Trials and Strategies to Address Multiple Testing
Creators: name: Gryaznov, Dmitry
name: Odutayo, Ayodele
name: Copsey, Bethan
name: Monk, Paul
name: Speich, Benjamin
name: Roberts, Corran
name: Vadher, Karan
name: Dutton, Peter
name: Hopewell, Sally
name: Briel, Matthias
name: Altman, Douglas  G.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: It is unclear how multiple treatment comparisons are managed in the analysis of multi-arm trials. We investigated strategies for managing multiple testing related to primary outcomes in multi-arm trials. Methods: We investigated clinical trial protocols approved[for full text, please go to the a.m. URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Einstellungen deutscher Pflegekräfte zur Nutzung Evidenzbasierter Medizin bzw. Evidenzbasierter Pflege im Pflegealltag in deutschen Krankenhäusern: Eine qualitative Studie
Creators: name: Steinhausen, Kirsten
name: Wünst, Nina
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Evidence based Medicine (EbM) und insbesondere Evidence based Nursing (EbN) gewinnen auch bei Pflegekräften im Pflegealltag immer mehr an Bedeutung. Während EbN international in vielen Ländern bereits gut etabliert ist, gibt es hier in Deutschland aufgrund[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00113
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00113, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00113, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
title: Selbstberichtete Einstellung, Kenntnisse und Fähigkeiten bezüglich der Anwendung evidenzbasierter Medizin in der alltäglichen Versorgungspraxis: eine nationale Umfrage unter Studierenden der medizinischen und gesundheitswissenschaftlichen Fakultäten in Ungarn
Creators: name: Csertő, Mónika
name: Berényi, Károly
name: Decsi, Tamás
name: Lohner, Szimonetta
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Evidenzbasierte Praxis kann nur dann realisiert werden, wenn medizinisches Fachpersonal evidenzbasierter Medizin (EBM) verbundene Terminologie versteht, allgemein positiv gegenüber EBM eingestellt ist und Fähigkeiten besitzt, die ermöglichen, EBM-Wissen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
“Compound Invisible Objects”: Moralischer Charakter, literarische Figur und die Gyges-Problematik bei Adam Smith und Eliza Haywood
Creators: name: Guttzeit, Gero
Publisher: name: Trier University
Year: 2022

description: A diachronic approach to the relationship between literature and philosophy since antiquity needs to include the field of rhetoric, regardless of whether it appears as a link or a disruption. This article discusses fundamental questions of rhetoric, philosophy, and poetics in the example of invisible characters and their moral qualities in antiquity and the mid-18th century. Plato’s mythical literary version of the Gyges legend in the “Republic” conceives of the invisible character as an illustration of the morally depraved nature of humans. In the following, I shall not trace this “Gyges problem” in the terms of influence studies but rather with an awareness of the ubiquity of ancient knowledge in philosophy and literature of the 18th century. I shall situate Adam Smith’s oft-discussed metaphor of the invisible hand in the context of his lectures on rhetoric, which were instrumental in founding the tradition of the Scottish New Rhetoric. I shall argue that invisibility forms a central element of Smith’s definition of character. The manifold implications of such a conception of invisible characters will then be illustrated using the example of Eliza Haywood’s “The Invisible Spy” (1755) and her conception of authorial ethos. Thus, the metaphor of invisibility proves itself to be of transhistorical relevance for the relationship between philosophy and literature, especially when they both turn to character – understood as fictional person, moral constitution, and the medium of the letter.
title: Fehlermanagement per Webinar: mit innovativen Medien zu mehr Patientensicherheit in der ambulanten Versorgung
Creators: name: Müller, Beate Sigrid
name: Gruber, Dania
name: Blazejewski, Tatjana
name: Pommée, Marina
name: Lüttel, Dagmar
name: Müller, Hardy
name: Rubin, Katharina
name: Kintrup, Andreas
name: Thomeczek, Christian
name: Heuzeroth, Reiner
name: Beyer, Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Strukturiertes Fehlermanagement mit Fehlerberichts- und Lernsystemen wird in Arztpraxen bisher nicht flächendeckend angewandt, obwohl der G-BA (Gemeinsamer Bundesausschuss) es fordert. Innerhalb des Innovationsfonds-geförderten Projektes CIRSforte wurden 184 teilnehmenden Arztpraxen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Gesundheitskiosk Billstedt-Horn – Selbstmanagementförderung durch Beratung in der ambulanten Versorgung
Creators: name: Muche-Borowski, Cathleen
name: Zimmermann, Thomas
name: Fischer, Alexander
name: Geibel, Irena
name: Scherer, Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Um die gesundheitliche Situation in den sozioökonomisch deprivierten Hamburger Stadtteilen Billstedt / Horn und Mümmelmannsberg mit ca. 110.000 Einwohner*innen zu verbessern, fördert der Innovationsfonds seit 2017 den Aufbau eines Gesundheitskiosks.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Nach Intervention in einem Krankenhaus verringerte sich der Verbrauch an unangemessenen schlafanstoßenden Arzneimitteln – eine Folge der Intervention?
Creators: name: Heinemann, Stephanie
name: Klemperer, Jonas
name: Himmel, Wolfgang
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Im Krankenhaus erhalten besonders ältere Patient/innen bei Ein- und Durchschlafproblemen schlafanstoßende Arzneimittel, die häufig zu den potentiell inadäquaten Medikamenten laut PRISCUS-Liste gehören. Zwischen April 2014 bis Juni 2017 haben[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Identifizierung von Barrieren der Leitlinienadhärenz am Beispiel einer Umfrage zur AWMF-S3-Leitlinie zu unkomplizierten bakteriellen ambulant erworbenen Harnwegsinfektionen bei erwachsenen Patienten (043 - 044)
Creators: name: Kranz, Jennifer
name: Schlager, Daniel
name: Mühlstädt, Sandra
name: Wagenlehner, Florian M. E.
name: Nagler, Julian
name: Schneidewind, Laila
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Zahlreiche Studien konnten eine mangelnde Leitlinienadhärenz, insbesondere bei der Therapie von Harnwegsinfektionen, zeigen. Die Nutzung von Leitlinien führt jedoch zu einer signifikanten Reduktion des Antibiotikagebrauchs, zur Senkung der Prävalenz multiresistenter[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
About sharing and commitment: the retrieval of biased and balanced irregular polysemes
Creators: name: Brocher, Andreas
name: Koenig, Jean-Pierre
name: Mauner, Gail
name: Stephani Foraker
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: We examined how the degree of semantic similarity between an ambiguous word’s meanings (homonyms vs. irregular polysemes) and meaning frequency (biased vs. balanced meanings) interact during lexical access and disambiguation. In Experiment 1, which was a continuous priming experiment, and with an ITI of 50 ms, we observed exhaustive access of meanings for all ambiguous words. With an ITI of 200 ms, we found a dominance effect for biased homonyms. There was no priming for biased irregular polysemes. For balanced homonyms and polysemes, we observed strong and roughly equivalent priming for target words associated with either meaning. In Experiment 2, using sentence reading, all ambiguous words elicited longer reading times in the absence of biasing context, while only biased and balanced homonyms also led to longer reading times in subsequent subordinate-biased context. Taken together, our data support a shared features model of irregular polyseme representation and retrieval.
title: ADCO, Abbaye de Cîteaux, 'Transcrits des titres de la layette marquée QQ, 1er cartable, liasses 1, 2 et 3' / Cartulaire d'Ouges (XVIIIe siècle, 2e moitié), Cart. 196 (11 H 938), f. 0057
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Abbaye de Cîteaux, 'Transcrits des titres de la layette marquée QQ, 1er cartable, liasses 1, 2 et 3' / Cartulaire d'Ouges (XVIIIe siècle, 2e moitié), Archives départementales de la Côte-d'Or, Cart. 196 (11 H 938), Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Abbaye de Cîteaux, 'Transcrits des titres de la layette marquée QQ, 1er cartable, liasses 1, 2 et 3' / Cartulaire d'Ouges (XVIIIe siècle, 2e moitié), Archives départementales de la Côte-d'Or, Cart. 196 (11 H 938), f. 0057, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
title: Perceived stress mediates the effect of yoga on quality of life and disease activity in ulcerative colitis. Secondary analysis of a randomized controlled trial
Creators: name: Koch, Anna Katharina
name: Schöls, Margarita
name: Langhorst, Jost
name: Dobos, Gustav
name: Cramer, Holger
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: Yoga positively affects health-related quality of life and disease activity in ulcerative colitis. The underlying modes of action remain unclear. Within the present study we hypothesized that patients´ perceived stress mediates the effects of yoga on health-related[for full text, please go to the a.m. URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Bedürfnisse und Wünsche der österreichischen Bevölkerung hinsichtlich einer für sie idealen hausärztlichen Versorgung
Creators: name: Hoffmann, Kathryn
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Allgemeinmedizin ist das hinsichtlich der Versorgungsrelevanz der Bevölkerung wichtigste und anspruchsvollste medizinische Fach. Unter gegebenen Rahmenbedingungen können dort bis zu 70-90 % aller Beratungs- und Behandlungsanlässe abschließend [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Cart. 188 (11 H 73), f. 0251v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0251v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0251v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
title: Synergie-Effekte in der Aphasietherapie: Sprachtherapie & bihemisphärische tDCS
Creators: name: Feil, Sarah
name: Strakeljahn, Frauke
name: Mylius, Veil
name: Eisenhut, Peter
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: In den letzten Jahren wurden die Zusammenhänge zwischen neuronaler Aktivität und den Effekten sprachtherapeutischer Behandlung bei Aphasie vermehrt untersucht. Dabei konnte in verschiedenen Studien ein positiver Einfluss von nicht-invasiver Hirnstimulation auf[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: More systematic reviews were registered in PROSPERO each year, but few records’ status was up-to-date
Creators: name: Rombey, Tanja
name: Doni, Katharina
name: Hoffmann, Falk
name: Pieper, Dawid
name: Allers, Katharina
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: Prospective registration of systematic reviews (SRs), e.g. in PROSPERO, the international prospective register for SRs, increases transparency. It may also increase methodological quality, decrease risk of bias, prevent unintended duplication of SRs and facilitate [for full text, please go to the a.m. URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Update: Umgang mit Interessenkonflikten im Programm für Nationale VersorgungsLeitlinien (NVL)
Creators: name: Schüler, Sabine
name: Nothacker, Monika
name: Härter, Martin
name: Schaefer, Corinna
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Nationale VersorgungsLeitlinien werden unter Anwendung schützender Faktoren (unabhängige Leitungsfunktionen, unabhängige Evidenzaufbereitung, Multidisziplinärität der Leitliniengruppe, strukturierter Konsensprozess unter neutraler Moderation) [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin