cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Predicting carbon dioxide and energy fluxes across global FLUXNET sites with regression algorithms
Creators: name: Tramontana, Gianluca
name: Jung, Martin
name: Camps-Valls, Gustau
name: Ichii, Kazuhito
name: Ráduly, Botond
name: Reichstein, Markus
name: Schwalm, Christopher R.
name: Arain, M. Altaf
name: Cescatti, Alessandro
name: Kiely, Gerard
name: Merbold, Lutz
name: Serrano-Ortiz, Penelope
name: Sickert, Sven
name: Wolf, Sebastian
name: Papale, Dario
Publisher: name: ETH Zurich
Year: 2016
Subjects: Machine learning
Carbon fluxes
Energy fluxes
FLUXNET
Remote sensing
FLUXCOM

description: Spatio-temporal fields of land–atmosphere fluxes derived from data-driven models can complement simulations by process-based land surface models. While a number of strategies for empirical models with eddy-covariance flux data have been applied, a systematic intercomparison of these methods has been missing so far. In this study, we performed a cross-validation experiment for predicting carbon dioxide, latent heat, sensible heat and net radiation fluxes across different ecosystem types with 11 machine learning (ML) methods from four different classes (kernel methods, neural networks, tree methods, and regression splines). We applied two complementary setups: (1) 8-day average fluxes based on remotely sensed data and (2) daily mean fluxes based on meteorological data and a mean seasonal cycle of remotely sensed variables. The patterns of predictions from different ML and experimental setups were highly consistent. There were systematic differences in performance among the fluxes, with the following ascending order: net ecosystem exchange (R2<0.5), ecosystem respiration (R2>0.6), gross primary production (R2>0.7), latent heat (R2>0.7), sensible heat (R2>0.7), and net radiation (R2>0.8). The ML methods predicted the across-site variability and the mean seasonal cycle of the observed fluxes very well (R2>0.7), while the 8-day deviations from the mean seasonal cycle were not well predicted (R2<0.5). Fluxes were better predicted at forested and temperate climate sites than at sites in extreme climates or less represented by training data (e.g., the tropics). The evaluated large ensemble of ML-based models will be the basis of new global flux products
description: Biogeosciences Discussions
description: ISSN:1810-6277
description: ISSN:1810-6285
Spatial and temporal variation of CO2 efflux along a disturbance gradient in a miombo woodland in Western Zambia
Creators: name: Merbold, Lutz
name: Ziegler, Waldemar
name: Mukelabai, Mukufute M.
name: Kutsch, Werner L.
Publisher: name: ETH Zurich
Year: 2010

description: Carbon dioxide efflux from the soil surface was measured over a period of several weeks within a heterogeneous Brachystegia spp. dominated miombo woodland in Western Zambia. The objectives were to examine spatial and temporal variation of soil respiration along a disturbance gradient from a protected forest reserve to a cut, burned, and grazed area outside, and to relate the flux to various abiotic and biotic drivers. The highest daily mean fluxes (around 12 μmol CO2 m−2 s−1) were measured in the protected forest in the wet season and lowest daily mean fluxes (around 1 μmol CO2 m−2 s−1) in the most disturbed area during the dry season. Diurnal variation of soil respiration was closely correlated with soil temperature. The combination of soil water content and soil temperature was found to be the main driving factor at seasonal time scale. There was a 75% decrease in soil CO2 efflux during the dry season and a 20% difference in peak soil respiratory flux measured in 2008 and 2009. Spatial variation of CO2 efflux was positively related to total soil carbon content in the undisturbed area but not at the disturbed site. Coefficients of variation of efflux rates between plots decreased towards the core zone of the protected forest reserve. Normalized soil respiration values did not vary significantly along the disturbance gradient. Spatial variation of respiration did not show a clear distinction between the disturbed and undisturbed sites and could not be explained by variables such as leaf area index. In contrast, within plot variability of soil respiration was explained by soil organic carbon content.

Three different approaches to calculate total ecosystem respiration (Reco) from eddy covariance measurements were compared to two bottom-up estimates of Reco obtained from chambers measurements of soil- and leaf respiration which differed in the consideration of spatial heterogeneity. The consideration of spatial variability resulted only in small changes of Reco when compared to simple averaging. Total ecosystem respiration at the plot scale, obtained by eddy covariance differed by up to 25% in relation to values calculated from the soil- and leaf chamber efflux measurements but without showing a clear trend.
description: Biogeosciences Discussions, 7 (4)
description: ISSN:1810-6277
description: ISSN:1810-6285
title: Optimization of the Innovation Readiness at the Bosch Engineering Center Vienna
Creators: name: Kavaldjian, Sevan
Publisher: name: TU Wien
Year: 2020
Subjects: subject: Innovation Management
subject: Optimization of Innovation Readiness
subject: Innovation Readiness Assessment
subject: Bosch Engineering Center Vienna
subject: Innovation Measurement

description: Every company needs a certain degree of Innovation Readiness to allow innovations to happen. In the course of this masterthesis measures to optimize the Innovation Readiness at the Bosch Engineering Center Vienna (BECVie) have been derived. At first a literature study was conducted to analyze the related work. An empirical approach was chosen to analyze the current state of the Innovation Readiness at BECVie. Therefore a survey was setup and conducted to measure the degree of approval for ten success factors, which have been assigned to di ̇erent stages of the innovation process. The ten success factors analyzed are: Anticipation of Market Trends, Strategy, Degree of Definition, Risk Management, Knowledge Management, Speed of Implementation, Market Access, Understanding of Interactions between Market and Product, Identification of Opportunities and Employee Participation.The weighted relative frequency analysis was used to analyze the results in detail. The degree of approval and the degree of rejection have been illustrated in a block diagram for the success factor as well as additional individual block diagrams for each success factor. The strongest and weakest success factors have been determined. Also results have been compared between di ̇erent age and function groups.The desired target state has been defined for the success factors, considering that BECVie has the main focus on product development from prototype to series. The aim was to avoid blockers in the innovation process by having a balanced level of approval for all the success factors.Subsequently suggestions for measures are defined to achieve the transition from the current state to the desired target state. Finally the conclusion and future outlook is presented to show how this work can be continued. Through the application of the defined suggested measures an optimization of the Innovation Readiness at BECVie is expected.
title: Stochastic evolutionary modelling of language change and applications to historical data
Creators: name: Guerrero Montero, Juan
Publisher: name: The University of Edinburgh
Year: 2025
Subjects: subject: Stochastic evolutionary models
subject: Language change
subject: Historical data
subject: Wright-Fisher model
subject: Iterated Bayesian Learning model

description: Language is a complex adaptive system whose properties emerge from a network of communicative interactions between speakers, modulated by their cognitive and social biases. In this conceptualisation, language change has a crucial role as the evolutionary process driving the adaptation of the language system. With the increasing availability of massive digital corpora datasets, stochastic evolutionary models of language change have the potential of providing empirical and quantitative explanations to the nature and origin of human language. In this thesis, I build on and develop such models in order to improve their applicability to historical data and their explanatory potential. First, I address limitations in the application to historical language data of the Wright-Fisher model from population genetic. By improving on the Beta-with- Spikes approximation to the Wright-Fisher transition probability, I am able to more accurately discern drift from selection in time series of language use. I apply this method to the detection of a phonological bias in the evolution of the past tense of English verbs. I further introduce a methodology able to detect abrupt changes in social dynamics in time series of language use by modelling them as discontinuities in the selective forces acting on the data. I benchmark this method by applying it to the detection of well-documented historical spelling reforms in Spanish. Secondly, I introduce an Iterated Bayesian Learning model for the evolution of grammatical structure through cultural transmission. Unlike previous evolutionary models of language change, this new model accounts for the coevolution of interrelated linguistic functions. By accounting for nontrivial communicative effects, the model reproduces features of natural languages absent from simpler models of cultural transmission, like communicative effects in the arising stationary distribution of grammars, and broken detailed balance generating directionality in change. I explore directionality by applying entropy production, a concept from non-equilibrium Statistical Mechanics, to a variety of models of language change. Finally, I show that this model of the cultural transmission of grammatical structure is equivalent to a set of co-evolving and interdependent Wright-Fisher processes, facilitating its application to empirical data. Its application to the evolution of relativisers and to the emergence of the periphrastic use of do in English highlights the potential of evolutionary models as tools for the empirical and quantitative testing of hypotheses in historical linguistics.
ESM3 from Identifying cryptic diversity with predictive phylogeography
Creators: name: Anahí Espíndola
name: Ruffley, Megan
name: Smith, Megan L.
name: Carstens, Bryan C.
name: Tank, David C.
name: Sullivan, Jack
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Supplementary Figure S6
Petrology of some prehistoric pottery from Mam Tor.
Creators: name: Guilbert, Graeme
name: Vince, A
Publisher: name: Archaeology Data Service
Year: 2002

description: The Derbyshire Archaeological Journal, 116, 49-59
description: Reports the results of thin-section analysis. A more detailed knowledge of clay-sources in the Peak District would be needed to expand on the origin of the matrix. The results throw some additional light on both the provenance of the pottery and the method of its preparation.
Protocol: Genome-Scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening
Creators: name: Joung, Julia
name: Konermann, Silvana
name: Gootenberg, Jonathan S.
name: Abudayyeh, Omar O.
name: Platt, Randall
name: Brigham, Mark D.
name: Sanjana, Neville E.
name: Zhang, Feng
Publisher: name: ETH Zurich
Year: 2016

description: Forward genetic screens are powerful tools for the unbiased discovery and functional characterization of specific genetic elements associated with a phenotype of interest. Recently, the RNA-guided endonuclease Cas9 from the microbial immune system CRISPR (clustered regularly interspaced short palindromic repeats) has been adapted for genome-scale screening by combining Cas9 with guide RNA libraries. Here we describe a protocol for genome-scale knockout and transcriptional activation screening using the CRISPR-Cas9 system. Custom- or ready-made guide RNA libraries are constructed and packaged into lentivirus for delivery into cells for screening. As each screen is unique, we provide guidelines for determining screening parameters and maintaining sufficient coverage. To validate candidate genes identified from the screen, we further describe strategies for confirming the screening phenotype as well as genetic perturbation through analysis of indel rate and transcriptional activation. Beginning with library design, a genome-scale screen can be completed in 6-10 weeks followed by 3-4 weeks of validation.
description: bioRxiv
Stone mould from the Derwent Valley, Derbyshire.
Creators: name: Parsons, Julien
Publisher: name: Archaeology Data Service
Year: 2002

description: The Derbyshire Archaeological Journal, 116, 60-67
description: Discussion of this primitive mould discovered in 1905 finds dating evidence inconclusive. The author finds that the balance of probability -- based on comparative data -- favours a Late Iron Age to Early Roman date.
Some observations on Romano-British brooch typology in the Peak District and adjacent areas.
Creators: name: Dearne, Martin J
Publisher: name: Archaeology Data Service
Year: 2002

description: The Derbyshire Archaeological Journal, 116, 68-76
description: A summary of the principal results of a survey undertaken in 1992 by the author concerning brooch production sites in the Peak District and surrounding areas as far as Derby, Manchester, Templeborough, and Chesterfield. It is thought that their value as datable objects has previously obscured their potential to yield socio-economic information as well as to define the stylistic individualism of craftspeople in specific areas.
Management matters; testing a mitigation strategy for nitrous oxide emissions using legumes on intensively managed grassland
Creators: name: Fuchs, Kathrin
name: Hörtnagl, Lukas
name: Buchmann, Nina
name: Eugster, Werner
name: Snow, Val
name: Merbold, Lutz
Publisher: name: ETH Zurich
Year: 2018

description: Biogeosciences Discussions
description: ISSN:1810-6277
description: ISSN:1810-6285
Domain-specific Language for Data-driven Design Time Analyses and Result Mappings for Logic Programs
Creators: name: Hahner, Sebastian
Publisher: name: Karlsruhe
Year: 2020

description: In der vernetzten Welt von Heute ist der Austausch von Daten für viele Anwendungen unerlässlich. Mit der zunehmenden Vernetzung und dem wachsenden Datenaufkommen wird die Gewährleistung von Sicherheit, Datenschutz und die Einhaltung rechtlicher Vorgaben immer wichtiger. Um diesen Anforderungen frühzeitig gerecht zu werden, können Datenflussanalysen zur Entwurfszeit eingesetzt werden. Durch explizite Modellierung der Daten und ihrer Eigenschaften kann das Architekturmodell automatisch gegen Datenflussbeschränkungen getestet werden. Diese Verifikationsansätze transformieren die modellierte Architektur in ihnen zugrunde liegende Formalismen wie z.B. logische Programme. Um die Aussagekraft der Beschränkungen zu erhöhen, müssen diese oft ebenfalls unter Nutzung des Formalismus ausgedrückt werden. Dies erfordert von den Architekten Kenntnisse über den Formalismus, die transformierte Architektur und die Verifikationsumgebung. Unser Ziel ist es, die Lücke zwischen der architektonischen Domäne und dem zugrundeliegenden Formalismus zu schließen, die bei der Formulierung von Datenflussbeschränkungen auftritt. Wir schlagen eine domänenspezifische Sprache (DSL) vor, die es Architekten ermöglicht, Einschränkungen bereits während der Definition der Architektur festzulegen. Durch die Verwendung der selben Terminologie, die auch zur Modellierung der Architektur eingesetzt wird, können individualisierte Beschränkungen ohne Kenntnisse des Überprüfungsprozesses formuliert werden. Zusätzlich stellen wir eine Abbildung der in unserer DSL formulierten Einschränkungen von der Architekturdomäne in den Formalismus vor. Analyseergebnisse werden in die Architekturdomäne zurück abgebildet, um deren Interpretation zu erleichtern. Die DSL basiert auf der Sammlung und Generalisierung bestehender Einschränkungen aus realen Fallstudien. Wir bewerten die Aussagekraft, Nutzbarkeit und Kompaktheit der DSL für Datenflussbeschränkungen unterschiedlicher Größe. Ungefähr 75% der untersuchten Beschränkungen können mit der ersten Version unserer DSL ausgedrückt werden, wobei bis zu 10-mal weniger Quelltext benötigt wird. Neben den Grundlagen der Datenflussmodellierung und Wissen über die Modellierungsumgebung sind keine weiteren Kenntnisse über den Transformations- oder Verifikationsmechanismus erforderlich. Zusätzlich untersuchen wir die Äquivalenz der Analyseergebnisse von Beschränkungen, die in unserer DSL formuliert wurden mit Beschränkungen, welche direkt unter Nutzung des Formalismus ausgedrückt wurden. In unseren Tests erreichen Beschränkungen, welche mit Hilfe unserer DSL formuliert wurden, eine 100%ige Ausbeute bei einer Präzision von 90%.
A Scoping Review of Children's Conceptualisations of Inclusive Play informed by Children’s Advisory Groups
Creators: name: Keeffe, Christina O
name: McNally, Sinead
Publisher: name: OSF
Year: 2021
Subjects: Children's Rights
Consultation
Developmental Psychology
Early Childhood Education
Education
Inclusion
Participation
Play

description: For decades, much contention and debate has dominated the literature as researchers have sought to understand and define play. In recent years, increasing emphasis has been placed on ascertaining children’s perspectives of play (Howard, 2019; Wood & Attfield, 2005), in line with a broader children’s rights-based approach and participatory research recommendations (United Nations Committee on the Rights of the Child, 2009; United Nations Convention on the Rights of the Child 1989; 2013). To investigate this further, this scoping review aims to add to the emerging body of evidence surrounding children’s perspectives of play and provide a comprehensive map of the available research in this area. A key aspect of this review involves consultation with children’s research advisory groups which is very much centred within a children’s rights-based approach (UNCRC, 1989; 2009) to ensure children have direct input into informing this research agenda and decision making. Overall, to the best of the authors’ knowledge, just two studies have attempted to systematically review evidence based on children’s perceptions of play (Goodhall & Atkinson, 2017; Graham et al., 2017) however no review to date has examined children’s conceptualisations of play more broadly as a construct. In this sense, the objectives of this study align with broader aims of scoping reviews, proposed by Arksey & O’Malley (2005), in that we aim to investigate the extent, range and nature of research within the field and consult directly with stakeholders as part of this process.
БАРКАМОЛ, ЖИСМОНИЙ ВА РУҲИЙ СОҒЛОМ ШАХСНИ ТАРБИЯЛАШДА ИХТИСОСЛАШТИРИЛГАН ЎҚУВ-ТАРБИЯ МУАССАСАЛАРИНИНГ ЎРНИ
Creators: name: Нарзиев, Шахзодбек
name: Қодирова, Ирода
Publisher: name: Zenodo
Year: 2024

description: Ушбу мақолада муаллиф ихтисослаштирилган мактаблар ўз фаолиятида тарбияланувчиларда қонунга итоаткорлик рухини шакллантириши, уларни ижтимоий ҳимоя қилиши ва ҳар томонлама ривожлантиришга ёрдам бериши, болаларнинг давлат таълим стандартлари асосида умумий ўрта таълим олиши учун шарт-шароитлар яратиш масалалари тўғрисида илмий қарашлар баён этилган.
Resolving the influence of temperature forcing through heat conduction on rockglacier dynamics: a numerical modelling approach
Creators: name: Cicoira, Alessandro
name: Beutel, Jan
name: Faillettaz, Jérôme
name: Gärtner-Roer, Isabelle
name: Vieli, Andreas
Publisher: name: ETH Zurich
Year: 2018

description: In recent years, observations have highlighted seasonal and inter-annual variability in rockglacier flow. Temperature forcing, through heat conduction, has been proposed as one of the key processes to explain these variations in kinematics. However, this mechanism has not yet been quantitatively assessed against real-world data.

We present a 1-D numerical modelling approach that couples heat conduction to an empirically derived creep model for ice-rich frozen soils. We use this model to investigate the effect of thermal heat conduction on seasonal and inter-annual variability in rockglacier flow. We compare the model results with borehole temperature data and surface velocity measurements from the PERMOS and PermaSense monitoring network in the Swiss Alps. We further conduct a model sensitivity analysis in order to resolve the importance of the different model parameters. Using the prescribed empirically derived rheology and observed near-surface temperatures, we are able to model the right order of magnitude of creep flow. However, both inter-annual and seasonal variability are underestimated by an order of magnitude, implying that heat conduction alone can not explain the observed variations. Therefore, non-conductive processes, likely linked to water availability, dominate the short-term velocity signal.
description: The Cryosphere Discussions
description: ISSN:1994-0432
description: ISSN:1994-0440
SUPPLEMENTARY MATERIAL - APPENDICES from Steady dynein forces induce flutter instability and propagating waves in mathematical models of flagella
Creators: name: P. V. Bayly
name: S. K. Dutcher
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biophysics
subject: Biological Engineering
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: Cilia and flagella are highly conserved organelles that beat rhythmically with propulsive, oscillatory waveforms. The mechanism that produces these autonomous oscillations remains a mystery. It is widely believed that dynein activity must be dynamically regulated (switched on and off, or modulated) on opposite sides of the axoneme to produce oscillations. A variety of regulation mechanisms have been proposed based on feedback from mechanical deformation to dynein force. In this paper, we show that a much simpler interaction between dynein and the passive components of the axoneme can produce coordinated, propulsive oscillations. Steady, distributed axial forces, acting in opposite directions on coupled beams in viscous fluid, lead to dynamic structural instability and oscillatory, wave-like motion. This ‘flutter’ instability is a dynamic analogue to the well-known static instability, buckling. Flutter also occurs in slender beams subjected to tangential axial loads, in aircraft wings exposed to steady air flow and in flexible pipes conveying fluid. By analysis of the flagellar equations of motion and simulation of structural models of flagella, we demonstrate that dynein does not need to switch direction or inactivate to produce autonomous, propulsive oscillations, but must simply pull steadily above a critical threshold force.
Factors controlling coccolithophore biogeography in the Southern Ocean
Creators: name: Nissen, Cara
name: Vogt, Meike
name: Münnich, Matthias
name: Gruber, Nicolas
name: Haumann, Alexander
Publisher: name: ETH Zurich
Year: 2018

description: The biogeography of Southern Ocean phytoplankton controls not only the local biogeochemistry, but also the export of macronutrients to lower latitudes and depth. Of particular relevance is the interaction between coccolithophores and diatoms, with the former being prevalent along the "Great Calcite Belt" (40–60°S), while diatoms tend to dominate the regions south of 60°S. To address the factors controlling coccolithophore distribution and the competition between them and diatoms, we use a regional high-resolution model (ROMS-BEC) for the Southern Ocean (24–78°S) that has been extended to include an explicit representation of coccolithophores. We assess the relative importance of bottom-up (temperature, nutrients, light) and top-down (grazing by zooplankton) factors in controlling Southern Ocean coccolithophore biogeography over the course of the growing season. In our simulations, coccolithophores are an important member of the Southern Ocean phytoplankton community, contributing 15% to annually integrated net primary productivity south of 30°S. Coccolithophore biomass is highest north of 50°S in late austral summer, when light levels are high and diatoms become silicate limited. Furthermore, we find top-down factors to be a major control on the relative abundance of diatoms and coccolithophores in the Southern Ocean. Consequently, when assessing potential future changes in Southern Ocean coccolithophore abundance, both abiotic (temperature, light, nutrients, pH) and biotic factors (interaction with diatoms and zooplankton) need to be considered.
description: Biogeosciences Discussions
description: ISSN:1810-6277
description: ISSN:1810-6285
The Roman fort at Little Chester, Derby: the East Wall and rampart, 1967-8.
Creators: name: Brassington, Maurice
Publisher: name: Archaeology Data Service
Year: 2002

description: The Derbyshire Archaeological Journal, 116, 77-92
description: Reports excavations at the site of a substantial mortared stone foundation, thought -- apparently correctly -- to form part of the east wall. Investigations uncovered three periods of occupation and pottery including coarse wares and samian. Extension of the area eastwards, the rampart, defensive wall and later robber trenches are also described.
A phenomenological study of culture and cultural beliefs on ethnic minority micro-business leaders in London.
Creators: name: Etemah, Jeff Ojotule
Publisher: name: Zenodo
Year: 2025

description: Micro-businesses are critically important for the economy with London seeing thegreatest number of new start-ups in the UK in recent years. Approximately 20% of microbusinessin London are owned by ethnic minorities and despite research exploringsuccess factors for micro-businesses in general, there is little understanding of specificfactors that impact on success of ethnic minority owned microbusinesses. Organisationalculture guides how organisational decisions are made and how employees interact witheach other and in micro-businesses the leader plays an influential role in shaping theorganisational culture. National culture and religion may influence the organisationalculture of ethnic minority-led micro-businesses through it leader, with calls seen in theliterature to develop a greater understanding of those influences. Taking aphenomenological approach, the lived experiences of 15 ethnic minority leaders inLondon from a range of sectors were examined using Interpretive PhenomenologicalAnalysis. Using paternalistic leadership theory as a theorical lens, findings highlighted therole that religion played in guiding decisions around both their lives and their businessesand were centred around morality benevolence and authority. These findings contributeto practice by highlighting the need for business support, especially policies aroundfinancial support, consider the impact of religion on decision making. From a theoricalperspective the study also develops paternalistic leadership theory to emphasise the roleof religion as a cross cutting influence in the dimensions of morality, benevolence, andauthority when applied to ethnic minority leaders.
title: Programme de la journée d'étude du projet CONPOSEE
Creators: name: LabexMed
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018

description: Programme de la journée d'étude "Elites économiques au sud de la Méditerranée : chantiers de recherche" du projet amorce CONPOSEE, des 3 et 4 décembre 2018
description: LEST
Experiences with a Decade of Wireless Sensor Networks in Mountain Cryosphere Research
Creators: name: Da Forno, Reto
name: Deline, Philip
name: Faillettaz, Jérome
name: Geiger, Alain
name: Gsell, Tonio
name: Hierold, Christofer
name: Hohensinn, Roland
name: Jacob, Romain
name: Lim, Roman
name: Limpach, Philippe
name: Müller, Michelle
name: Neyer, Fabian
name: Ravanel, Ludovic
name: Roman, Cosmin
name: Sutton, Felix
name: PermaSense Team
name: Beutel, Jan
Publisher: name: ETH Zurich
Year: 2017

description: Geophysical Research Abstracts
description: ISSN:1029-7006
description: ISSN:1607-7962
Biologically-informed interpretable deep learning techniques for BMI prediction and gene interaction detection
Creators: name: Hequet, Chloe
Publisher: name: The University of St Andrews
Year: 2024
Subjects: subject: Deep learning
subject: Genetics
subject: FOS: Biological sciences
subject: Artificial intelligence
subject: Neural networks
subject: Genotype
subject: Phenotype
subject: Interpretable AI
subject: Prediction
subject: Body mass index
subject: Gene gene interaction
subject: FTO gene

description: The analysis of genetic point mutations at the population level can offer insights into the genetic basis of human traits, which in turn could potentially lead to new diagnostic and treatment options for heritable diseases. However, existing genetic data analysis methods tend to rely on simplifying assumptions that ignore nonlinear interactions between variants. The ability to model and describe nonlinear genetic interactions could lead to both improved trait prediction and enhanced understanding of the underlying biology. Deep Learning models offer the possibility of automatically learning complex nonlinear genetic architectures, but it is currently unclear how best to optimise them for genetic data. It is also essential that any models be able to “explain” what they have learned in order for them to be used for genetic discovery or clinical applications, which can be difficult due to the black-box nature of DL predictors. This thesis addresses a number of methodological gaps in applying explainable DL models end-to-end on variant-level genetic data. We propose novel methods for encoding genetic data for deep learning applications and show that feature encodings designed specifically for genetic variants offer the possibility of improved model efficiency and performance. We then benchmark a variety of models for the prediction of Body Mass Index using data from the UK Biobank, yielding insights into DL performance in this domain. We then propose a series of novel DL model interpretation methods with features optimised for biological insights. We first show how these can be used to validate that the network has automatically replicated existing knowledge, and then illustrate their ability to detect complex nonlinear genetic interactions that influence BMI in our cohort. Overall, we show that DL model training and interpretation procedures that have been optimised for genetic data can be used to yield new insights into disease aetiology.
title: Sexual Orientation Body Image and Sexual Functioning
Creators: name: Finch Jr., Charlie Bryan
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1991

description: Comparisons were made between 78 heterosexual men, 113 heterosexual women, 55 gay men, and 54 lesbians (N = 300) on a variety of body-image and sexual-functioning measures. In comparison to heterosexual men, gay men were more cognitively invested in their appearance, less satisfied with their muscularity and physical fitness, and were less invested in their fitness. Gay men also evidenced a relatively stronger sex drive and experienced premature ejaculation less frequently and inhibited orgasm more frequently. In comparison to heterosexual women, lesbians were more satisfied with their body areas, less cognitively and behaviorally invested in their appearance, and less worried about being or becoming overweight. Lesbians also evidenced a relatively stronger sex drive, were more orgasmic, and experienced problems with arousal and dyspareunia less frequently and problems with sexual aversion or avoidance more frequently. Correlations between body-image and sexual-functioning measures suggested unique relationships among groups. A discussion of the findings and suggestions for future research are given.
Transcription of Pitx1 in Ctenophorus pictus (CP) and Pogona vitticeps (PV) embryonic limbs from Expression of a hindlimb-determining factor Pitx1 in the forelimb of the lizard Pogona vitticeps during morphogenesis
Creators: name: Melville, Jane
name: Sumitha Hunjan
name: McLean, Felicity
name: Mantziou, Georgia
name: Boysen, Katja
name: Parry, Laura J.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology

description: With over 9000 species, squamates, which include lizards and snakes, are the largest group of reptiles and second-largest order of vertebrates, spanning a vast array of appendicular skeletal morphology. As such, they provide a promising system for examining developmental and molecular processes underlying limb morphology. Using the Central Bearded Dragon (Pogona vitticeps) as the primary study model, we examined limb morphometry throughout embryonic development and characterized the expression of three known developmental genes (GHR, Pitx1 and Shh) from early embryonic stage through to hatchling stage via reverse transcription quantitative polymerase chain reaction (RT-qPCR) and immunohistochemistry (IHC). In this study, all genes were found to be transcribed in both the forelimb and hindlimbs of P. vitticeps. While the highest level of GHR expression occurred at the hatchling stage, Pitx1 and Shh expression was greatest earlier during embryogenesis, which coincides with the onset of the differentiation between forelimb and hindlimb length. We compared our finding of Pitx1 expression—a hindlimb-determining gene—in the forelimbs of P. vitticeps to that in a closely related Australian agamid lizard, Ctenophorus pictus, where we found Pitx1 expression to be more highly expressed in the hindlimb compared with the forelimb during early and late morphogenesis—a result consistent to that found across other tetrapods. Expression of Pitx1 in forelimbs has only rarely been documented, including via in situ hybridization in a chicken and a frog. Our findings, from both RT-qPCR and IHC, indicate that further research across a wider range of tetrapods is needed to more fully understand evolutionary variation in molecular processes underlying limb morphology.
title: gobelet G14 (Barrier  Luginbühl 2021)
Creators: name: Bibracte
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: gobelet

description: Gobelet trapu  panse ovoïde  col rentrant développé parcouru par une baguette  pied annulaire
The Quigrich or Crosier of St. Fillan, - with a notice of its present existence in Canada. Communicated to Lord Talbot de Malahide by his Excellency Sir Edmund W. Head, Bart., Governor-General of Canada
Creators: name: Way, Albert
name: Stuart, John
Publisher: name: Archaeology Data Service
Year: 2008

description: The Archaeological Journal, 16, 41-52
description: Communicated to Lord Talbot de Malahide by his Excellency Sir Edmund W. Head, Bart., Governor-General of Canada
title: 03 –Entretien avec les azmari Almaz et Ṭašu Gʷäbäzé : chant avec des double-sens
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: chant
semäna warq

description: Chant.
title: gobelet G14 (Barrier  Luginbühl 2021)
Creators: name: Luginbühl, Thierry
name: Barrier, Sylvie
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: gobelet
subject: Artefact
subject: ACQUISITION

description: Modèle 3D
Densifying Sparse VIO: a Mesh-based approach using Structural Regularities
Creators: name: Rosinol, Antoni
Publisher: name: ETH Zurich
Year: 2018
Subjects: Visual Inertial Odometry
Dense Mapping
State Estimation
SLAM
Robotics
info:eu-repo/classification/ddc/004
Data processing, computer science

description: The ideal vision system for an autonomous robot would not only provide the robot’s position and orientation (localization), but also an accurate and complete model of the scene (mapping). While localization information allows for controlling the robot, a map of the scene allows for collision-free navigation; combined, a robot can achieve full autonomy.

Visual Inertial Odometry (VIO) algorithms have shown impressive localization results in recent years. Unfortunately, typical VIO algorithms use a point cloud to represent the scene, which is hardly usable for other tasks such as obstacle avoidance or path planning.

In this work, we explore the possibility of generating a dense and consistent model of the scene by using a 3D mesh, while making use of structural regularities to improve both mesh and pose estimates. Our experimental results show that we can achieve a 26% more accurate pose estimates than state-of-the-art VIO algorithms when enforcing structural constraints, while also building a 3D mesh which provides a denser and more accurate map of the scene than a classical point cloud. We also show that our approach does not rely on assumptions about the scene and is general enough to work when structural regularities are not present. --> The ideal vision system for an autonomous robot would not only provide the robot’s position and orientation (localization), but also an accurate and complete model of the scene (mapping). While localization information allows for controlling the robot, a map of the scene allows for collision-free navigation; combined, a robot can achieve full autonomy.

Visual Inertial Odometry (VIO) algorithms have shown impressive localization results in recent years. Unfortunately, typical VIO algorithms use a point cloud to represent the scene, which is hardly usable for other tasks such as obstacle avoidance or path planning.

In this work, we explore the possibility of generating a dense and consistent model of the scene by using a 3D mesh, while making use of structural regularities to improve both mesh and pose estimates. Our experimental results show that we can achieve a 26\% more accurate pose estimates than state-of-the-art VIO algorithms when enforcing structural constraints, while also building a 3D mesh which provides a denser and more accurate map of the scene than a classical point cloud. We also show that our approach does not rely on assumptions about the scene and is general enough to work when structural regularities are not present.
Supplementary material from Complementary learning systems within the hippocampus: a neural network modelling approach to reconciling episodic memory with statistical learning
Creators: name: Schapiro, Anna C.
name: Turk-Browne, Nicholas B.
name: Botvinick, Matthew M.
name: Norman, Kenneth A.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Neuroscience
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Slots in CA1; Supplementary Figure 1. Timecourse of pair structure learning; Supplementary Figure 2. Undeveloped TSP; Supplementary Figure 3. Inhibition and pair learning; Supplementary Figure 4. Inhibition and community structure; Supplementary Table 1. Parameters for layer sizes and inhibition, as implemented in the Emergent simulation environment; Supplementary Table 2. Parameters for projections between layers.
In den Höhlen der Macht.
Creators: name: Stoppel, Hendrik
Publisher: name: Ethik und Gesellschaft
Year: 2024

description: Jeder weiß, was er meint, wenn er von Wirklichkeit spricht, und im Normalfall gehen Menschen davon aus, dass sie diese Wirklichkeit mit anderen Menschen teilen. Nicht erst seit der COVID-Pandemie stellt sich aber immer wieder die Erfahrung ein, dass einige  Menschen im Glauben an umfassende Verschwörungen von einer ganz anderen Wirklichkeit ausgehen. Um diesen Wirklichkeiten kritisch begegnen zu können, bedarf es einer Theorie, die die faktische Pluralität beschreiben und gleichzeitig Wege zur Kritik jeglichen Wirklichkeitsbegriffs aufzeigt. Eine solche Theorien findet sich in der Philosophie Hans Blumenbergs. Mit seinem Entwurf als Denkrahmen wird die Eigenart verschwörungstheoretischer Wirklichkeitsbegriffe beschrieben und werden schließlich Möglichkeiten zu Kritik aufgezeigt.
description: Ethik und Gesellschaft, Nr. 1 (2024): Ge|teilte Wirklichkeit
title: Correspondance avec Christophe Girard (Mairie de Paris)
Creators: name: Girard, Christophe (1956-....)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/Calames-20193111135799622
description: created: start=1993-10-14;end=2006-06-07
title: 04 –Entretien avec les azmari Almaz et Ṭašu Gʷäbäzé : double-sens
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: semäna warq

description: (quasiment pas traduit)
Survey and excavation at Dirtlow, Bradwell Moor
Creators: name: Dearne, Martin J
Publisher: name: Archaeology Data Service
Year: 2013

description: The Derbyshire Archaeological Journal, 117, 5-16
description: A description of the survey and selective excavation of the Dirtlow site by Martin J. Dearne and students of the former Department of Ancient History and Classical Archaeology, University of Sheffield, in 1987 and 1988. The lithic material found is described.
›Schwarzer Feminismus‹ – zur Notwendigkeit und Herausforderung einer intersektionalen Perspektiverweiterung theologischer Anthropologien
Creators: name: Engelmann, Barbara
Publisher: name: Ethik und Gesellschaft
Year: 2024

description: Sexismus und Rassismus sind nach wie vor ein gegenwärtiges Problem in gesellschaftlichen und kirchlich-theologischen Wirklichkeiten. Dabei erweist sich die theologische Anthropologie als besonders anfällig für die Übernahme und Verfestigung sexistischer und rassistischer Vorstellungen, sei es bewusst oder unbewusst. Trotz wachsender Bemühungen zur Dekonstruktion und einer gesteigerten Sensibilität für patriarchale und koloniale Strukturen in der theologischen Anthropologie wird oft vernachlässigt, dass Ausschlusstendenzen nicht isoliert auftreten, sondern sich gegenseitig verstärken, marginalisieren oder sogar neue Formen der Diskriminierung schaffen können. Die hier besprochene Ausgangsthese betont daher die Notwendigkeit einer intersektionalen Perspektive in theologischen Anthropologien, um die vorhandenen Mechanismen der Ausgrenzung und Diskriminierung kritisch zu hinterfragen und letztendlich zu überwinden. Andernfalls besteht das Risiko, dass Theologien, die Diversität ausschließen, eine Realität postulieren und möglicherweise konstruieren, die von vielen nicht mehr geteilt wird.
description: Ethik und Gesellschaft, Nr. 1 (2024): Ge|teilte Wirklichkeit
title: 02_0846
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Erfahrung (in) geteilter Wirklichkeit.
Creators: name: Rhein, Philipp
Publisher: name: Ethik und Gesellschaft
Year: 2024

description: Mit Erfahrungen ist vorsichtig umzugehen – jedenfalls in politischen und wissenschaftlichen Debatten im Kontext der Krisen der Gegenwartsgesellschaft.  Die politischen und sozialen Krisen der Gegenwart werden schließlich häufig mit »Erfahrungen« von Menschen erklärt und – umgekehrt – mit politisch motivierten Behauptungen über Erfahrungen befeuert. Derlei essentialisierte Erfahrungsbegrifflichkeit und ihre politische Indienstnahme schließen den Raum des Politischen und behindern politische Deliberation. In der politischen Auseinandersetzung besteht die Gefahr, dass diskursiv konstruierte Erfahrungen unversöhnlicher Polarisierungen auf der einen Seite, Erfahrungswelten eines hyperpolitischen Individualismus auf der anderen Seite jede Form des politischen Ausgleichs und Konsenses behindern. Der Beitrag setzt sich auf drei Ebenen kritisch mit dem Erfahrungsbegriff im Kontext dieser Diskurslage auseinander. Durch Rückgriff auf wissenssoziologische Theorie wird ein überindividuell konzipierter und ent-essentialisierter Erfahrungsbegriff vorgeschlagen, der bei der kritischen Analyse der politischen Gegenwartsverhältnisse hilfreich sein soll. Mit ihm lässt sich eine Reflexion anstoßen in Zeiten, in denen Erfahrungen hypostasiert, d. h. essentialisiert werden, darin sozialtheoretisch unkritisch aufgewertet werden und in ihrer Bedeutung für das politische Geschehen der Gegenwart überschätzt werden. Ein wissenssoziologisch-konstruktivistischer Erfahrungsbegriff leistet einen Beitrag dazu, einen politischen Begriff von Erfahrung »wiederzugewinnen«.
description: Ethik und Gesellschaft, Nr. 1 (2024): Ge|teilte Wirklichkeit
A re-survey of the ringbanks on Parwich Moor and excavation of four ringbanks at Parwich.
Creators: name: Makepeace, G A
name: Shimwell, D W
Publisher: name: Archaeology Data Service
Year: 2013

description: The Derbyshire Archaeological Journal, 117, 17-25
description: After a preliminary look at the site at Parwich in 1990 suggested there were considerably more ringbanks than the survey made by John Lomas in 1962, another survey was carried out in the summer of 1991. The increase in number of ringbanks found probably arose because of changes in land use in the area. The site is centred on grid reference SK173575.
Resonanzräume schaffen: Interkulturalität zwischen machtvollen Diskursen und sozialer Praxis
Creators: name: Klinglmayr, Theresa
Publisher: name: Ethik und Gesellschaft
Year: 2024

description: Gegenwärtige Gesellschaften sind angesichts ihres pluralisierten Charakters maßgeblich auf Kommunikation über vielfältige Differenzen hinweg angewiesen. Der vorliegende Beitrag setzt sich mit Herausforderung interkultureller Kommunikation im Kontext aktueller gesellschaftlicher Wandlungsprozesse und Diskursverschiebungen auseinander. Dabei wird dafür argumentiert, den sozial und diskursiv konstruierten Charakter kultureller Zuschreibungen stärker zu berücksichtigen. Anknüpfend an eine kritisch-phänomenologische Perspektive werden Fremdheitserfahrungen in Bezug auf ihre interaktiven und diskursiven Dynamiken beschrieben. Basierend darauf wird ein resonanztheoretischer Ansatz vorgeschlagen, um klassische Modelle gelingender interkultureller Kommunikation zu ergänzen und eine Perspektive auf differenzsensible Kommunikation zu entwickeln.
description: Ethik und Gesellschaft, Nr. 1 (2024): Ge|teilte Wirklichkeit