cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ral small GTPase signaling and oncogenesis: More than just 15minutes of fame
Creators: name: Martin, Timothy
name: Reiner, David
name: Der, Channing
name: Gentry, Leanna
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Since their discovery in 1986, Ral (Ras-like) GTPases have emerged as critical regulators of diverse cellular functions. Ral-selective guanine nucleotide exchange factors (RalGEFs) function as downstream effectors of the Ras oncoprotein, and the RalGEF-Ral signaling network comprises the third best characterized effector of Ras-dependent human oncogenesis. Because of this, Ral GTPases as well as their effectors are being explored as possible therapeutic targets in the treatment of RAS mutant cancer. The two Ral isoforms, RalA and RalB, interact with a variety of downstream effectors and have been found to play key and distinct roles in both normal and neoplastic cell physiology including regulation of vesicular trafficking, migration and invasion, tumor formation, metastasis, and gene expression. In this review we provide an overview of Ral biochemistry and biology, and we highlight recent discoveries.
Population biology of the green porcelain crab Petrolisthes armatus (Crustacea: Porcellanidae) in a tropical estuarine bay of northeastern Brazil
Creators: name: BEZERRA, Luis Ernesto Arruda
name: ROCHA, Sergio Schwarz Da
name: VIEIRA, Alanna
name: OLIVEIRA, Guilherme De
name: ALMEIDA, Alexandre Oliveira
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: The aim of this study was to investigate the population biology of the green porcelain crab Petrolisthes armatus in an estuarine area of northeastern Brazil. Individuals were monthly sampled (February 2011-January 2012) during the spring low tide. Four transects, 10 m apart from each other and perpendicular to the shoreline were delimited in the rocky zone of a beach, comprising an area of approximately 861 m². Crab sampling was carried out using 0.25-m² plots (10 equally spaced plots were sampled from each transect per month). A total of 836 individuals were collected: 401 males (48%), 220 non-ovigerous females (26.3%), and 215 ovigerous females (25.7%). Ovigerous females were significantly larger than males and non-ovigerous females, while males were significantly larger than non-ovigerous females. The overall sex ratio of 1:0.9 did not differ significantly from the expected 1:1. The highest abundance (19.8 ind.m-2) was observed in transect 3, in the mid-intertidal, suggesting zonation and edge effect. Ovigerous females were recorded in all months except in May 2011, suggesting continuous reproduction and the mean fecundity was 145 ± 121 embryos. There was a significant correlation between carapace width and number of embryos. Although the study area showed some signs of disturbance caused by anthropogenic action, the population of P. armatus was stable in its natural environment.
ANALIZA CULTURII ORGANIZAȚIONALE ÎN COMPANIILE MULTINAȚIONALE.pdf
Creators: name: Grigore, Oana
name: Ciotlos, Stefan
Publisher: name: figshare
Year: 2020
Subjects: subject: 200209 Multicultural, Intercultural and Cross-cultural Studies
subject: FOS: Other humanities
subject: 150301 Business Information Management (incl. Records, Knowledge and Information Management, and Intelligence)
subject: FOS: Economics and business

description: Importanța conceptului de cultură organizațională este subliniată de marile companii ce depun eforturi considerabile pentru a construi și menține o cultură organizațională performantă: de la recrutare, felul în care este organizat mediul de lucru, interacțiunea angajaților, până la implicarea acestora în luarea deciziilor. Prezentul studiu se bazează pe chestionarul propus de Hofstede pentru a identifica și analiza elementele de specificitate culturală din cadrul Veo și Xerox din Iași, utilizând un eșantion de 122 de angajați proveniți din cele două companii anterior menționate. Rezultatele cercetării arată că firmele au culturi organizaționale asemănătoare, evidențiindu-se, însă, diferențe în modul în care indivizii se identifică cu organizația sau cu felul muncii și în ceea ce privește intensitatea controlului exercitat de superiori. Cu toate acestea, prezentul studiu evidențiază influența culturii naționale și a valorilor angajaților asupra culturii organizaționale a celor două companii analizate.
Website von: CYBATHLON bewegt Mensch und Technik / CYBATHLON moving people and technology mit der Original-URL http://www.cybathlon.ethz.ch
Creators: name: ETH Zürich, Informatikdienste
Publisher: name: ETH-Bibliothek, Hochschularchiv der ETH Zürich
Year: 2018
Subjects: Spiegelung der Website, geharvestet mit dem Crawler Heritrix. Beim Aufrufen der Website kann eine Fehlermeldung betreffend Silbentrennung (hyphenator.js) erscheinen; der Fehler hat keine Auswirkung auf Inhalt oder Darstellung der Website.

description: deutsch und englisch
Website von: Digital Building Technologies DBT mit der Original-URL http://dbt.arch.ethz.ch
Creators: name: ETH Zürich, Informatikdienste
Publisher: name: ETH-Bibliothek, Hochschularchiv der ETH Zürich
Year: 2018
Subjects: Spiegelung der Website, geharvestet mit dem Crawler Heritrix. Beim Aufrufen der Website kann eine Fehlermeldung betreffend Silbentrennung (hyphenator.js) erscheinen; der Fehler hat keine Auswirkung auf Inhalt oder Darstellung der Website. Webarchivierung unvollständig.

description: englisch
Website von: Chair of Mathematical and Physical Geodesy mit der Original-URL http://www.mpg.igp.ethz.ch
Creators: name: ETH Zürich, Informatikdienste
Publisher: name: ETH-Bibliothek, Hochschularchiv der ETH Zürich
Year: 2018
Subjects: Spiegelung der Website, geharvestet mit dem Crawler Heritrix. Beim Aufrufen der Website kann eine Fehlermeldung betreffend Silbentrennung (hyphenator.js) erscheinen; der Fehler hat keine Auswirkung auf Inhalt oder Darstellung der Website. Zweite Sprachversion (DE) auch auf der Original-Website nicht vorhanden.

description: deutsch und englisch
Association Between Autozygosity and Major Depression: Stratification Due to Religious Assortment
Creators: name: Davies, Gareth
name: Hudziak, James
name: Brooks, Andrew
name: Sullivan, Patrick
name: de Geus, Eco
name: Penninx, Brenda
name: Smit, Johannes
name: Bartels, Meike
name: Hottenga, Jouke-Jan
name: Ehli, Erik
name: Boomsma, Dorret
name: Xiao, Xiangjun
name: Abdellaoui, Abdel
name: Willemsen, Gonneke
name: Smit, Dirk
name: Scheet, Paul
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The effects of inbreeding on the health of offspring can be studied by measuring genome-wide autozygosity as the proportion of the genome in runs of homozygosity (Froh) and relate Froh to outcomes such as psychiatric phenotypes. To successfully conduct these studies, the main patterns of variation for genome-wide autozygosity between and within populations should be well understood and accounted for. Within population variation was investigated in the Dutch population by comparing autozygosity between religious and non-religious groups. The Netherlands have a history of societal segregation and assortment based on religious affiliation, which may have increased parental relatedness within religious groups. Religion has been associated with several psychiatric phenotypes, such as major depressive disorder (MDD). We investigated whether there is an association between autozygosity and MDD, and the extent to which this association can be explained by religious affiliation. All Froh analyses included adjustment for ancestry-informative principal components (PCs) and geographic factors.
Website von: Department of Information Technology and Electrical Engineering / Departement Informationstechnologie und Elektrotechnik D-ITET mit der Original-URL https://www.ee.ethz.ch
Creators: name: ETH Zürich, Informatikdienste
Publisher: name: ETH-Bibliothek, Hochschularchiv der ETH Zürich
Year: 2018
Subjects: Spiegelung der Website, geharvestet mit dem Crawler Heritrix. Beim Aufrufen der Website kann eine Fehlermeldung betreffend Silbentrennung (hyphenator.js) erscheinen; der Fehler hat keine Auswirkung auf Inhalt oder Darstellung der Website.

description: englisch und deutsch
Website von: Center for Security Studies mit der Original-URL http://www.css.ethz.ch
Creators: name: ETH Zürich, Informatikdienste
Publisher: name: ETH-Bibliothek, Hochschularchiv der ETH Zürich
Year: 2018
Subjects: Spiegelung der Website, geharvestet mit dem Crawler Heritrix. Beim Aufrufen der Website kann eine Fehlermeldung betreffend Silbentrennung (hyphenator.js) erscheinen; der Fehler hat keine Auswirkung auf Inhalt oder Darstellung der Website.

description: deutsch und englisch
(235) Rebecca Dennistoun Speirs
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The National Longitudinal Study of Adolescent to Adult Health (Add Health) Sibling Pairs Genome-Wide Data
Creators: name: Tabor, Joyce
name: Halpern, Carolyn
name: Killeya-Jones, Ley
name: Harris, Kathleen Mullan
name: Whitsel, Eric
name: Boardman, Jason
name: McQueen, Matthew
name: Domingue, Benjamin
name: Smolen, Andrew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Here we provide a detailed description of the genome-wide information available on the National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pair subsample (Harris et al., 2012). A total of 2020 samples were genotyped (including duplicates) arising from 1946 Add Health individuals from the sibling pairs subsample. After various steps for quality control (QC) and quality assurance (QA), we have high quality genome-wide data available on 1,888 individuals. In this report, we first highlight theQC and QA steps that were taken to prune the data of poorly performing samples and genetic markers. We further estimate the pairwise biological relationships using genome-wide data and compare those estimates to the assumed relationships in Add Health. Additionally, using genome-wide data from knownregional reference populations from Europe, West Africa, North and South America, Japan and China, weestimate the relative genetic ancestry of the respondents. Finally, rather than conducting a traditional cross-sectional genome-wide association study (GWAS) of body mass index (BMI), we opted to utilize the extensivepublicly available genome-wide information to conduct a weighted genome-wide association study (GWAS) of longitudinal BMI while accounting for both family and ethnic variation.
On the presence of Cantherhines macrocerus (Hollard, 1853) in the Principe Island (Gulf of Guinea)
Creators: name: HERRERO-BARRENCUA, Aketza
name: JABER, Jose Raduan
name: ABREU, António Domingos
name: HAROUN, Ricardo
name: CASTRO, José Juan
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: This paper reports the presence of Cantherhines macrocerus (Hollard, 1853) in shallow waters of Principe Island (São Tomé e Príncipe, Gulf of Guinea). This sighting represents the first time that the Whitespotted filefish is collected in the tropical waters of the Gulf of Guinea (Western Equatorial Africa).
The Einstein-Maxwell Equations and Conformally Kaehler Geometry
Creators: name: LeBrun, Claude
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C55 (Primary), 14J26, 53C25, 53C80, 83C15, 83C22 (Secondary)

description: Page's Einstein metric on CP_2 # (-CP_2) is conformally related to an extremal Kaehler metric. Here we construct a family of conformally Kähler solutions of the Einstein-Maxwell equations that deforms the Page metric, while sweeping out the entire Kaehler cone of CP_2 # (-CP_2).The same method also yields analogous solutions on every Hirzebruch surface. This allows us to display infinitely many geometrically distinct families of solutions of the Einstein-Maxwell equations on the smooth 4-manifolds S^2 x S^2 and CP_2 # (-CP_2).
description: 41 pages. LaTeX2e
Morphological Fractions of Galaxies in WINGS Clusters: revisiting the Morphology-Density Paradigm
Creators: name: Fasano, G.
name: Poggianti, B. M.
name: Bettoni, D.
name: Donofrio, M.
name: Dressler, A.
name: Vulcani, B.
name: Moretti, A.
name: Gullieuszik, M.
name: Fritz, J.
name: Omizzolo, A.
name: Cava, A.
name: Couch, W. J.
name: Ramella, M.
name: Biviano, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the Morphology-Density and Morphology-Radius relations (T-Sigma and T-R, respectively) obtained from the WINGS database of galaxies in nearby clusters. Aiming to achieve the best statistics, we exploit the whole sample of galaxies brighter than MV=-19.5 (5,504 objects), stacking up the 76 clusters of the WINGS survey altogether. Using this global cluster sample, we find that the T-Sigma relation holds only in the inner cluster regions (R<1/3xR200), while the T-R relation keeps almost unchanged over the whole range of local density. A couple of tests and two sets of numerical simulations support the robustness of these results against the effects of the limited cluster area coverage of the WINGS imaging. The above mentioned results hold for all cluster masses (X-ray luminosity and velocity dispersion) and all galaxy stellar masses (M). The strength of the T-Sigma relation (where present) increases with increasing M, while this effect is not found for the T-R relation. Noticeably, the absence/presence of subclustering determines the presence/absence of the T-Sigma relation outside the inner cluster regions, leading us to the general conclusion that the link between morphology and local density is preserved just in dynamically evolved regions. We hypothesize that some mechanism of morphological broadening/redistribution operates in the intermediate/outer regions of substructured (non relaxed) clusters, producing a strong weakening of the T-Sigma relation.
description: 21 pages, 17 figures, 7 tables, accepted for publication in MNRAS, online material at: ftp://ftp.oapd.inaf.it/pub/fasano/maps.pdf
Branching random walks in random environment: A survey
Creators: name: König, Wolfgang
Publisher: name: Weierstrass Institute
Year: 2020
Subjects: subject: Multitype branching random walk
subject: random potential
subject: parabolic Anderson model
subject: Feynman--Kac-type formula
subject: annealed moments
subject: large deviations
subject: 60J80
subject: 60J55
subject: 60F10
subject: 60K37

description: We consider branching particle processes on discrete structures like the hypercube in a random fitness landscape (i.e., random branching/killing rates). The main question is about the location where the main part of the population sits at a late time, if the state space is large. For answering this, we take the expectation with respect to the migration (mutation) and the branching/killing (selection) mechanisms, for fixed rates. This is intimately connected with the parabolic Anderson model, the heat equation with random potential, a model that is of interest in mathematical physics because of the observed prominent effect of intermittency (local concentration of the mass of the solution in small islands). We present several advances in the investigation of this effect, also related to questions inspired from biology.
Length-weight relationships of nine common demersal Elasmobranch species from the Eastern Mediterranean
Creators: name: YEMİŞKEN, Emre
name: ERYILMAZ, Lütfiye
name: MEGALOFONOU, Persefoni
name: YILDIZ, Taner
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: Length-weight relationships were estimated for common demersal elasmobranch species in two different fishing regions - Northeastern Aegean Sea (NEAS) and North Eastern Levantine Sea (NELS) - in the Eastern Mediterranean. All individuals were collected using bottom trawl fishing vessels from September 2014 to April 2016. Nonlinear models were used and the values of parameter b of the length-weight relationship W = aLb ranged from 2.2931 to 3.4455 from NELS and 3.0519 to 3.2089 from NEAS. Notwithstanding that the total length measurements of Scyliorhinus canicula showed differences between NELS and NEAS, there were no significant differences according to the sampling periods and the depths in the study.
Cocaine treatment and prenatal environment interact to disrupt intergenerational maternal behavior in rats.
Creators: name: Walker, Cheryl
name: McMurray, Matthew
name: Middleton, Christopher
name: Johns, Josephine
name: Elliott, Jay
name: Haslup, Amber
name: Elliott, Deborah
name: Jarrett, Thomas
name: Hofler, Vivian
name: Joyner, Paul
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: The link between impaired maternal behavior (MB) and cocaine treatment could result from drug-induced decreases in maternal reactivity to offspring, prenatal drug exposure (PDE) in offspring that could alter their ability to elicit MB, or the interaction of both, which could subsequently impair MB of the 1st-generation dams. Following chronic or intermittent cocaine or saline treatment during gestation, rat dams rearing natural or cross-fostered litters were compared along with untreated dams for MB. Untreated 1st-generation females with differentially treated rearing dams and PDE were tested for MB with their natural litters. The authors report disruptions in MB in dams and their 1st-generation offspring, attributable to main and interaction effects of maternal treatment, litter PDE, and rearing experience.
Social deficits, stereotypy and early emergence of repetitive behavior in the C58/J inbred mouse strain
Creators: name: Moy, Sheryl
name: Young, Nancy
name: Crawley, Jacqueline
name: Ryan, Bryce
name: Bodfish, James
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Mouse lines with behavioral phenotypes relevant to symptoms in neurodevelopmental disorders may provide models to test hypotheses about disease etiology and to evaluate potential treatments. The present studies were designed to confirm and expand earlier work on the intriguing behavioral profile of the C58/J inbred strain, including low social approach and aberrant repetitive movements. Additional tests were selected to reflect aspects of autism, a severe neurodevelopmental disorder characterized by emergence of symptoms early in life, higher prevalence in males, social deficits and abnormal repetitive behavior. Mice from the C57BL/6J inbred strain, which has a similar genetic lineage and physical appearance to C58/J, served as a comparison group. Our results revealed that C58/J mice display elevated activity levels by postnatal day 6, which persist into adulthood. Despite normal olfactory ability, young adult male C58/J mice showed deficits in social approach in the three-chambered choice assay and failed to demonstrate social transmission of food preference. In contrast, female C58/J mice performed similarly to female C57BL/6J mice in both social tests. C58/J mice of both sexes demonstrated abnormal repetitive behaviors, displaying excessive jumping and back flipping in both social and non-social situations. These stereotypies were clearly evident in C58/J pups by postnatal days 20–21, and were also observed in C58/J dams during a test for maternal behavior. Overall, the strain profile for C58/J, including spontaneously developing motor stereotypies emerging early in the developmental trajectory, and social deficits primarily in males, models multiple components of the autism phenotype.
Behavioral deficits in an Angelman syndrome model: Effects of genetic background and age
Creators: name: Riddick, Natallia
name: Yashiro, Koji
name: Burns, Andrew
name: Baker, Lorinda
name: Riday, Thorfinn
name: Philpot, Benjamin
name: Nonneman, Randal
name: Huang, Hsien-Sung
name: Moy, Sheryl
name: Nikolova, Viktoriya
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Angelman syndrome (AS) is a severe neurodevelopmental disorder associated with disruption of maternally inherited UBE3A (ubiquitin protein ligase E3A) expression. At the present time, there is no effective treatment for AS. Mouse lines with loss of maternal Ube3a (Ube3am–/p+) recapitulate multiple aspects of the clinical AS profile, including impaired motor coordination, learning deficits, and seizures. Thus, these genetic mouse models could serve as behavioral screens for preclinical efficacy testing, a critical component of drug discovery for AS intervention. However, the severity and consistency of abnormal phenotypes reported in Ube3am–/p+ mice can vary, dependent upon age and background strain, which is problematic for the detection of beneficial drug effects. As part of an ongoing AS drug discovery initiative, we characterized Ube3am–/p+ mice on either a 129S7/SvEvBrd-Hprtb-m2 (129) or C57BL/6J (B6) background across a range of functional domains and ages to identify reproducible and sufficiently large phenotypes suitable for screening therapeutic compounds. The results from the study showed that Ube3am–/p+ mice have significant deficits in acquisition and reversal learning in the Morris water maze. The findings also demonstrated that Ube3am–/p+ mice exhibit motor impairment in a rotarod task, hypoactivity, reduced rearing and marble-burying, and deficient fear conditioning. Overall, these profiles of abnormal phenotypes can provide behavioral targets for evaluating effects of novel therapeutic strategies relevant to AS.
Deep Networks Can Resemble Human Feed-forward Vision in Invariant Object Recognition
Creators: name: Kheradpisheh, Saeed Reza
name: Ghodrati, Masoud
name: Ganjtabesh, Mohammad
name: Masquelier, Timothée
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Deep convolutional neural networks (DCNNs) have attracted much attention recently, and have shown to be able to recognize thousands of object categories in natural image databases. Their architecture is somewhat similar to that of the human visual system: both use restricted receptive fields, and a hierarchy of layers which progressively extract more and more abstracted features. Yet it is unknown whether DCNNs match human performance at the task of view-invariant object recognition, whether they make similar errors and use similar representations for this task, and whether the answers depend on the magnitude of the viewpoint variations. To investigate these issues, we benchmarked eight state-of-the-art DCNNs, the HMAX model, and a baseline shallow model and compared their results to those of humans with backward masking. Unlike in all previous DCNN studies, we carefully controlled the magnitude of the viewpoint variations to demonstrate that shallow nets can outperform deep nets and humans when variations are weak. When facing larger variations, however, more layers were needed to match human performance and error distributions, and to have representations that are consistent with human behavior. A very deep net with 18 layers even outperformed humans at the highest variation level, using the most human-like representations.
(230) William Cunningham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
New record of Loricophyra stresemanni (Ciliophora: Suctorea) as epibiont on nematodes from the Indian Ocean and notes on the genus Loricophrya
Creators: name: CHATTERJEE, Tapas
name: NANAJKAR, Mandar
name: DOVGAL, Igor
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: The article is dedicated to the re-discovery of suctorian ciliate Loricophrya stresemanni found on nematodes from Miramar bay (Arabian Sea), Goa, west coast of India. The morphological characterizations of collected ciliate specimens and redescription of the genus Loricophrya are presented. Thecacineta spirinae Allgén, 1934 and Paracineta scanica Allgén 1934 are transferred into Loricophrya as Loricophrya spirinae (Allgén, 1934) comb. nov. and Loricophrya scanica (Allgén, 1934) comb. nov. correspondingly.
(232) James Playfair
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(233) Jane Speirs
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sub $k_B T$ micro-electromechanical irreversible logic gate
Creators: name: Lopez-Suarez, Miquel
name: Neri, Igor
name: Gammaitoni, Luca
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: In modern computers, computation is performed by assembling together sets of logic gates. Popular gates like AND, OR, XOR, processing two logic inputs and yielding one logic output, are often addressed as irreversible logic gates where the sole knowledge of the output logic value, is not sufficient to infer the logic value of the two inputs. Such gates are usually believed to be bounded to dissipate a finite minimum amount of energy determined by the input-output information difference. Here we show that this is not necessarily the case, by presenting an experiment where a OR logic gate, realized with a micro electromechanical cantilever, is operated with energy well below the expected limit, provided the operation is slow enough and frictional phenomena are properly addressed.
Heparan sulfate deficiency in autistic postmortem brain tissue from the subventricular zone of the lateral ventricles
Creators: name: Vasconcellos, Amy
name: Blanchard, D. Caroline
name: Corley, Michael
name: Blanchard, Robert
name: Pearson, Brandon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Abnormal cellular growth and organization have been characterized in postmortem tissue from brains of autistic individuals, suggestive of pathology in a critical neurogenic niche, the subventricular zone (SVZ) of the brain lateral ventricles (LV). We examined cellular organization, cell proliferation, and constituents of the extracellular matrix such as N-sulfated heparan sulfate (HS) and laminin (LAM) in postmortem brain tissue from the LV-SVZ of young to elderly individuals with autism (n = 4) and age-matched typically developing (TD) individuals (n = 4) using immunofluorescence techniques. Strong and systematic reductions in HS immunofluorescence were observed in the LV-SVZ of the TD individuals with increasing age. For young through mature, but not elderly, autistic pair members, HS was reduced compared to their matched TDs. Cellular proliferation (Ki67+) was higher in the autistic individual of the youngest age-matched pair. These preliminary data suggesting that HS may be reduced in young to mature autistic individuals are in agreement with previous findings from the BTBR T+tf/J mouse, an animal model of autism; from mice with genetic modifications reducing HS; and with genetic variants in HS-related genes in autism. They suggest that aberrant extracellular matrix glycosaminoglycan function localized to the subventricular zone of the lateral ventricles may be a biomarker for autism, and potentially involved in the etiology of the disorder.
Entropic uncertainty bound for open pointer-based simultaneous measurements of conjugate observables
Creators: name: Heese, Raoul
name: Freyberger, Matthias
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We discuss the information entropy for a general open pointer-based simultaneous measurement and show how it is bound from below. This entropic uncertainty bound is a direct consequence of the structure of the entropy and can be obtained from the formal solution of the measurement dynamics. Furthermore, the structural properties of the entropy allow us to give an intuitive interpretation of the noisy influence of the pointers and the environmental heat bath on the measurement results.
description: 26 pages, 1 figure
Occurrence of brephoepipelagic fishes in the stomach contents of large pelagic predators in the southwestern equatorial Atlantic Ocean
Creators: name: VASKE, Teodoro
name: TEIXEIRA LESSA, Rosangela Paula
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: The brephoepipelagic fishes are characterized by having larvae and juveniles that live in the pelagic environment and displace to the bottom in coastal water when adults. In the oceanic region of northeastern Brazil their presence was studied as part of the diet of 1,990 stomachs analyzed from 15 large predators, with the presence of 3,562 individuals of brephoepipelagic fishes. Seven species, with a higher dominance of Dactylopterus volitans (87.7% in number) were found, followed by other genera and species, Balistes sp. (4.35%), Diodon sp. (3.43%), Acanthurus sp. (1.88%), Holocentrus adscensionis (1.54%), Acanthostracion sp.(0.87%), Fistularia sp. (0.34%), and Monacanthus sp. (0.25%). Their main predators were the dolphinfish (Coryphaena hippurus), tunas (Thunnus spp.), and billfishes (Istiophoridae). The presence and abundance in the open ocean may have origin from islands and oceanic banks in the northeast region, also along the coast, where they disperse to open waters due to currents and eddies, becoming available for large predators between at a size between 2 and 14 cm.
(229) [Susan?] [Speirs]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
On the maximal size of large-average and ANOVA-fit submatrices in a Gaussian random matrix
Creators: name: Nobel, Andrew
name: Sun, Xing
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: We investigate the maximal size of distinguished submatrices of a Gaussian random matrix. Of interest are submatrices whose entries have an average greater than or equal to a positive constant, and submatrices whose entries are well fit by a two-way ANOVA model. We identify size thresholds and associated (asymptotic) probability bounds for both large-average and ANOVA-fit submatrices. Probability bounds are obtained when the matrix and submatrices of interest are square and, in rectangular cases, when the matrix and submatrices of interest have fixed aspect ratios. Our principal result is an almost sure interval concentration result for the size of large average submatrices in the square case.
Diversity and distribution of sea slugs (Mollusca: Gastropoda: Heterobranchia) in two sites of the Caribbean coast of Honduras
Creators: name: CAVIEDES, Verónica
name: CAMACHO-GARCÍA, Yolanda E.
name: CERVERA, Juan Lucas
name: CARRASCO, Juan Carlos
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: Although several studies on the marine heterobranch gastropod fauna have been conduc ted in the Caribbean region, there is still a lack of knowledge on this group in Honduras. This study presents a checklist of "sea slug" species (Mollusca: Gastropoda: Heterobranchia) resulting from a series of samples taken at two very shallow areas in the Caribbean coast of Honduras, the Blanca Jeannette Kawas Fernández National Park and the Chachaguala Lagoon, located in the Cuyamel-Omoa National Park. A total of 194 specimens were collec ted and identified. They belong to 30 species, in 5 orders, 14 of which represent new records for Honduras. The present study increased the number of sea slugs known in the Caribbean coasts of Honduras to 93 species, and increased the degree of knowledge of marine heterobranchs of this region.
Further evidence that muscarinic cholinergic receptors of 1321N1 astrocytoma cells couple to a guanine nucleotide regulatory protein that is not N i
Creators: name: Evans, T
name: Harden, T K
name: Martin, M W
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1985

description: Inhibitory coupling of receptors to adenylate cyclase previously has been shown to be relatively sensitive to inactivation by alkylation with N-ethylmaleimide (NEM). Modification of the inhibitory guanine nucleotide regulatory protein, Ni, has been proposed to be responsible for this effect. The effects of NEM on GTP-sensitive binding of carbachol to muscarinic cholinergic receptors has been compared in a cell line (1321N1 human astrocytoma cells) in which these receptors stimulate phosphoinositide breakdown and in a cell line (NG108-15 neuroblastoma X glioma cells) in which activation of these receptors results in inhibition of adenylate cyclase. Pretreatment of membrane preparations from 1321N1 cells with NEM resulted in a concentration-dependent decrease in the extent of pertussis toxin-catalysed [32P]ADP-ribosylation of a 41 000 Da protein previously proposed to be the alpha subunit of Ni. Under conditions where 32P-labelling of Ni in 1321N1 membranes was reduced by NEM by 90%, no effect was observed on the extent of guanine nucleotide-sensitive high-affinity binding of carbachol to muscarinic cholinergic receptors. In contrast, treatment of NG108-15 membranes with NEM under the same conditions resulted in complete loss of high-affinity guanine nucleotide sensitive binding of carbachol. These results illustrate another difference between the muscarinic receptor population of these two cell lines, and support the previous proposal that muscarinic receptors of 1321N1 cells couple to a guanine nucleotide regulatory protein that is not Ni.
(231) Janet Lang
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Evidence that muscarinic cholinergic receptors selectively interact with either the cyclic AMP or the inositol phosphate second-messenger response systems
Creators: name: Harden, T K
name: Hughes, A R
name: Hepler, J R
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: The relative capacities of muscarinic cholinergic receptor (MR) and bradykinin (BK)-receptor activation to increase phosphoinositide hydrolysis and to increase cytosolic Ca2+ were compared in NG108-15 neuroblastoma x glioma and 1321N1 human astrocytoma cells. In 1321N1 cells, the muscarinic cholinergic agonist carbachol and BK each stimulated a concentration-dependent accumulation of inositol phosphates (K0.5 approximately 10 microM and approximately 10 nM respectively) and a rapid increase in cytosolic Ca2+ as determined by quin2 fluorescence. In NG108-15 cells, BK alone stimulated a pertussis-toxin-insensitive accumulation of inositol phosphates (K0.5 approximately 10 nM) under conditions in which pertussis toxin completely inhibited MR-mediated inhibition of adenylate cyclase. BK also stimulated a rapid increase in cytosolic Ca2+ in NG108-15 cells. In contrast, no MR-mediated increase in phosphoinositide hydrolysis or change in cytosolic Ca2+ concentration was observed in NG108-15 cells. These results support the idea that MR selectively interact with either the cyclic AMP or the inositol phosphate second-messenger systems.
(226) Margaret Cunningham Speirs
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(228) John Speirs (snr)
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Concentrations of trace-metal elements in the superficial sediment and the marine magnophyte, Posidonia oceanica (L) Delile, 1813 from the Gulf of Skikda (Mediterranean coast, East of Algeria)
Creators: name: ZEGHDOUDI, Fadila
name: TANDIR, Larbi M.
name: OUALI, Naouel
name: HADDIDI, Iman
name: RACHEDI, Mounira
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: The level of trace metal elements TME (Cd, Pb, Cr, Cu and Zn) was determined in adult leaves of Posidonia oceanica, the retained superficial sediment in three stations from Skikda Gulf over the period from winter 2010 to summer 2011. The distribution of trace metals in sediment and plant showed a significant spatiotemporal fluctuation. Analyses identified samples of the Mollo station as the most contaminated ones. Indeed, the contamination of P. oceanica tissues reflected the contamination of the site. The contamination index (CI) was calculated and confirmed the presence of a polymetallic pollution in Cd, Pb, Cr and Zn, whose highest levels were recorded during the rainy season and the lowest during the dry period. The levels of the TME in the sediment and plant decreased in the following order (Cr > Pb > Zn > Cu > Cd) and (Pb > Cr > Zn > Cu > Cd), respectively, whatever the season. In seagrass beds, seasonal variation was related to the physiological state of the plant. Indeed, the highest concentrations of Cu and Zn were found in fall, and the lowest ones were recorded in spring, a significant difference was noticed in the level of TME in the two compartments (ANOVA, p < 0.001).
Elements for a future EBSA (Ecologically or Biologically Significant marine Area) process in the Alborán Sea and connected areas. A case study for north-south cooperation
Creators: name: TALAMO, Daniela
name: RIERA, Rodrigo
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: The political shape of the Alborán region is characterized b y a clear division between the north and south coasts, and national interests predominate both north and south in terms of the maritime map, with a resulting mosaic of jurisdictions that facilitates neither bilateral nor multilateral agreements. The delimitation between different jurisdictions in the Alborán Sea rises to what could be termed a "jurisdictional asymmetry", a consequence of the heterogeneous nature of the legal systems of adjacent jurisdictions. The north-south asymmetry can also be seen in the existence of two distinct and greatly differing socio-economic and cultural models. The north has high or very high human development indicators, whereas south has average human development indicators. All these factors are a source of instability and have a significant impact on the way in which political relationships interact in the Alborán Sea. An integrated governance framework as set out in Ecologically or Biologically Significant Marine Areas (EBSAs) process may offer appropriate horizontal tools to help policy makers and economic and environmental actors to join up their policies, interlink their activities and optimize the use of marine and coastal space in an environmentally sustainable manner.
First record of Shagreen ray Leucoraja fullonica (Linnaeus, 1758) in Syrian coastal waters (eastern Mediterranean)
Creators: name: SAAD, Adib
name: ALKUSAIRY, Hasan
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2019

description: On 8 March 2018, one individual of Leucoraja fullonica was caught during a trawl survey conducted in Syrian territorial water at a depth of 340 m. This specimen was an immature female, measured 365 mm -total length, 210 mm - disc width, and weighted 183.2 g. This paper reports the first documented record of the species in Syrian waters and in the Levantine basin.
Calcium-dependent properties of CIB binding to the integrin alphaIIb cytoplasmic domain and translocation to the platelet cytoskeleton.
Creators: name: Brittain, J E
name: Sondek, J
name: Parise, L V
name: Naik, U P
name: Shock, D D
name: Alahari, S K
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: The alphaIIbbeta3 integrin receives signals in agonist-activated platelets, resulting in its conversion to an active conformation that binds fibrinogen, thereby mediating platelet aggregation. Fibrinogen binding to alphaIIbbeta3 subsequently induces a cascade of intracellular signalling events. The molecular mechanisms of this bi-directional alphaIIbbeta3-mediated signalling are unknown but may involve the binding of proteins to the integrin cytoplasmic domains. We reported previously the sequence of a novel 22-kDa, EF-hand-containing, protein termed CIB (calcium- and integrin-binding protein) that interacts specifically with the alphaIIb cytoplasmic domain in the yeast two-hybrid system. Further analysis of numerous tissues and cell lines indicated that CIB mRNA and protein are widely expressed. In addition, isothermal titration calorimetry indicated that CIB binds to an alphaIIb cytoplasmic-domain peptide in a Ca(2+)-dependent manner, with moderate affinity (K(d), 700 nM) and 1:1 stoichiometry. In aggregated platelets, endogenous CIB and alphaIIbbeta3 translocate to the Triton X-100-insoluble cytoskeleton in a parallel manner, demonstrating that the cellular localization of CIB is regulated, potentially by alphaIIbbeta3. Thus CIB may contribute to integrin-related functions by mechanisms involving Ca(2+)-modulated binding to the alphaIIb cytoplasmic domain and changes in intracellular distribution.