cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Long-term open-label extension study of the safety and efficacy of intrathecal idursulfase-IT in patients with neuronopathic mucopolysaccharidosis II
Creators: name: Harmatz, Paul
name: Alexanderian, David
name: Whiteman, David A.H.
name: Burton, Barbara K.
name: Wu, Yuna
name: Muenzer, Joseph
name: Hale, Michael
name: Jones, Simon A.
name: Gutiérrez-Solana, Luis González
name: Bratkovic, Drago
name: SHP609-302 study group
name: Inbar-Feigenberg, Michal
name: Guffon, Nathalie
name: Yee, Karen S.
name: Ruiz-Garcia, Matilde
Publisher: name: Elsevier
Year: 2022

description:
Enzyme replacement therapy with weekly infused intravenous (IV) idursulfase is effective in treating somatic symptoms of mucopolysaccharidosis II (MPS II; Hunter syndrome). A formulation of idursulfase for intrathecal administration (idursulfase-IT) is under investigation for the treatment of neuronopathic MPS II. Here, we report 36-month data from the open-label extension (NCT02412787) of a phase 2/3, randomized, controlled study (HGT-HIT-094; NCT02055118) that assessed the safety and efficacy of monthly idursulfase-IT 10 mg in addition to weekly IV idursulfase on cognitive function in children older than 3 years with MPS II and mild-to-moderate cognitive impairment. Participants were also enrolled in this extension from a linked non-randomized sub-study of children younger than 3 years at the start of idursulfase-IT therapy. The extension safety population comprised 56 patients who received idursulfase-IT 10 mg once a month (or age-adjusted dose for sub-study patients) plus IV idursulfase (0.5 mg/kg) once a week. Idursulfase-IT was generally well tolerated over the cumulative treatment period of up to 36 months. Overall, 25.0% of patients had at least one adverse event (AE) related to idursulfase-IT; most treatment-emergent AEs were mild in severity. Of serious AEs (reported by 76.8% patients), none were considered related to idursulfase-IT treatment. There were no deaths or discontinuations owing to AEs. Secondary efficacy analyses (in patients younger than 6 years at phase 2/3 study baseline; n = 40) indicated a trend for improved Differential Ability Scale-II (DAS-II) General Conceptual Ability (GCA) scores in the early idursulfase-IT versus delayed idursulfase-IT group (treatment difference over 36 months from phase 2/3 study baseline: least-squares mean, 6.8 [90% confidence interval: -2.1, 15.8; p = 0.2064]). Post hoc analyses of DAS-II GCA scores by genotype revealed a clinically meaningful treatment effect in patients younger than 6 years with missense variants of the iduronate-2-sulfatase gene (IDS) (least-squares mean [standard error] treatment difference over 36 months, 12.3 [7.24]). These long-term data further suggest the benefits of idursulfase-IT in the treatment of neurocognitive dysfunction in some patients with MPS II. After many years of extensive review and regulatory discussions, the data were found to be insufficient to meet the evidentiary standard to support regulatory filings.
Étude exploratoire des effets de la pandémie de COVID-19 sur la santé des personnes ayant des troubles de santé mentale au Canada
Creators: name: Ngendakuriyo, Narcisse
Publisher: name: My University
Year: 2022

description: La pandémie de la COVID-19 a bouleversé la vie de toute la population mondiale en général et celle du Canada en particulier. Tous les domaines de la vie humaine ont été touchés mais tout le monde n’a pas été affecté de la même façon. Dans le cas de ce mémoire de type exploratoire, cette recherche se penche sur les effets de la pandémie de COVID-19 sur la santé des personnes ayant des troubles de santé mentale au Canada. Il est important de se demander si le confinement dû à la pandémie de COVID-19 a eu des effets qui pourraient contribuer à exacerber le risque de décompensation chez les personnes ayant déjà des troubles de santé mentale. Quels sont les facteurs ayant contribué à la détérioration de leur santé mentale pendant la période de confinement ? Les déterminants sociaux de la santé auraient-ils contribué à augmenter ces troubles de santé mentale ? Cette recherche se base sur une revue de littérature qui s’articule autour des mots clé comme pandémie, anxiété, dépression, COVID-19, isolement, confinement, troubles anxieux/de santé mentale et déterminants sociaux de la santé pour mieux développer et répondre à la question de recherche. Les résultats de cette recherche de type exploratoire montrent que les personnes aux prises avec les troubles de santé mentale ont été plus touchées que le reste de la population étant donné leur vulnérabilité psychologique, économique et sociale. La recherche montre aussi que les mesures mises en place pour diminuer la propagation du virus ont exacerbé et augmenté les niveaux d’anxiété et de dépression chez les populations en général, et les personnes ayant des troubles de santé mentale en particulier. Cela implique de nouveaux programmes sanitaires, sociaux et financiers.
OCTAVE-S Implementation Guide, Version 1
Creators: name: Albert, Cecilia
name: Dorofee, Audrey J.
name: Stevens, James F.
name: Woody, Carol C.
Publisher: name: Carnegie Mellon University
Year: 2005
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: The Operationally Critical Threat, Asset, and Vulnerability Evaluation (OCTAVE) approach defines a risk-based strategic assessment and planning technique for security. OCTAVE is a self-directed approach, meaning that people from an organization assume responsibility for setting the organizations security strategy. OCTAVE-S is a variation of the approach tailored to the limited means and unique constraints typically found in small organizations (less than 100 people). OCTAVE-S is led by a small, interdisciplinary team (three to five people) of an organizations personnel who gather and analyze information, producing a protection strategy and mitigation plans based on the organizations unique operational security risks. To conduct OCTAVE-S effectively, the team must have broad knowledge of the organizations business and security processes, so it will be able to conduct all activities by itself.
Laboratoire SCIENCEX - André Guez
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (2 pages).
description: Autre destinataire : Caroline Petit.
Lettre de Antoine Gouan à Jean-François Séguier, 1764-12-09
Creators: name: Gouan, Antoine
name: Gouan, Antoine
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Botanique

description: [fol. 78] Supposé que le paquet vous arrive cette semaine, vous m’obligerez de ne point montrer quelques jours la Flora parce que l’exemplaire que je dois donner à mon mécène n’est pas encore relié et qu’il est naturel et décent qu’il soit servi le premier.

Mon cher M. Séguier, j’ai reçu tous vos paquets et me hâte de vous en faire mes sincères remerciements. Je les ai toute d esuite parcouru et n’ai rien trouvé en plantes sèches que je n’eus déjà depuis longtemps. Vous aviez bien raison de m’en prévenir. J’en ai pourtant gardé plusieurs uniquement pour confronter avec les miennes quand au nom, car vous savez fort bien qu’il y en avait de mal étiquetées. Je viens de séparer pour nos amis ce qui pouvait leur convenir. Je profiterai de la première occasion pour vous le renvoyer et y trouverez dedans un exemplaire de la flore que je viens de recevoir et vous prie instament de ne pas dire que vous la teniez de moi, car le libraire ne m’en a donné que 12 et serai fort embarrassé pour vendre à plusieurs savants les politesses que j’en ai reçue. Il y a longtemps que je vous dois mes petites productions et que vous avez un droit assuré et s’il n’y en eut qu’un il eut été pour vous. Comptez toujours sur mon amitié et vous prie de me conserver la vôtre.
 Je suis très sincèrement tout à vous

 Gouan

A Montpellier le 9 décembre 1764.
description: Source: [établissement de conservation] Nîmes, Bibliothèque Carré d'Art [cote] ms. 144, fol. 78
On the finiteness of the classifying space of diffeomorphisms of reducible three manifolds
Creators: name: Nariman, Sam
Publisher: name: arXiv
Year: 2021
Subjects: subject: Geometric Topology (math.GT)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 57R50, 57R19, 57M60, 57M07, 55R40, 57S05, 58D05

description: Kontsevich conjectured that $\text{BDiff}(M, \text{rel }\partial)$ has the homotopy type of a finite CW complex for all compact $3$-manifolds with non-empty boundary. Hatcher-McCullough proved this conjecture when $M$ is irreducible. We prove a homological version of Kontsevich's conjecture. More precisely, we show that $\text{BDiff}(M, \text{rel }\partial)$ has finitely many nonzero homology groups, each finitely generated, when $M$ is a connected sum of irreducible $3$-manifolds that each have a nontrivial and non-spherical boundary.
description: 22 pages, thoroughly revised. to appear in Forum of Mathematics, Sigma
Dispersive detection of radio-frequency dressed states
Creators: name: Jammi, Sindhu
name: Pyragius, Tadas
name: Bason, Mark G.
name: Florez, Hans Marin
name: Fernholz, Thomas
Publisher: name: arXiv
Year: 2018
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We introduce a method to dispersively detect alkali atoms in radio-frequency dressed states. In particular, we use dressed detection to measure populations and population differences of atoms prepared in their clock states. Linear birefringence of the atomic medium enables atom number detection via polarisation homodyning, a form of common path interferometry. In order to achieve low technical noise levels, we perform optical sideband detection after adiabatic transformation of bare states into dressed states. The balanced homodyne signal then oscillates independently of field fluctuations at twice the dressing frequency, thus allowing for robust, phase-locked detection that circumvents low-frequency noise. Using probe pulses of two optical frequencies, we can detect both clock states simultaneously and obtain population difference as well as the total atom number. The scheme also allows for difference measurements by direct subtraction of the homodyne signals at the balanced detector, which should technically enable quantum noise limited measurements with prospects for the preparation of spin squeezed states. The method extends to other Zeeman sublevels and can be employed in a range of atomic clock schemes, atom interferometers, and other experiments using dressed atoms.
description: 14 pages, 11 figures Revised structure. Some theory placed in annex
Ineficacia inicial de la autorización para el tratamiento de datos personales otorgada en la contratación contemporánea por adhesión
Creators: name: Grande Jiménez, Lukas
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Nulidad - Derecho
subject: Clausulas - Derecho
subject: Derechos humanos
subject: Autorización
subject: Datos personales
subject: Habeas data
subject: Tratamiento de datos personales
subject: Negocio jurídico
subject: Contrato de adhesión

description: La presente investigación busca determinar cuáles son los mecanismos sancionatorios idóneos para garantizar la tutela efectiva del derecho fundamental al habeas data en el marco de la contratación contemporánea, en los casos donde la autorización del titular para el tratamiento de datos personales no fue conferida de manera previa, expresa e informada; partiendo de los aportes de la teoría general del contrato, que ayudan a comprender la naturaleza jurídica y el alcance del contenido de esa declaración, a fin de determinar si las figuras sancionatorias actualmente previstas en el ordenamiento jurídico son suficientes para proteger este bien fundamental.
description: This investigation pretends determine what are those suitable sanctioning mechanisms for warranting the effective protection of the fundamental right to habeas data in the framework of contemporary contracting, in those cases where individual’s consent had not been conferred previously, expressly and informedly, starting on the contributions of general theory of contract, that helps to comprehending the legal nature and content’s scope of that declaration, with the purpose of determining if sanctioning figures actually provided by legal system are enough for protecting this fundamental good.
Intrathecal idursulfase-IT in patients with neuronopathic mucopolysaccharidosis II: Results from a phase 2/3 randomized study
Creators: name: Hale, Michael
name: Yee, Karen S.
name: Bratkovic, Drago
name: Alexanderian, David
name: HGT-HIT-094 Study Group
name: Jones, Simon A.
name: Muenzer, Joseph
name: Whiteman, David A.H.
name: Burton, Barbara K.
name: Wu, Yuna
name: Inbar-Feigenberg, Michal
name: Guffon, Nathalie
name: Gutiérrez-Solana, Luis González
name: Harmatz, Paul
name: Ruiz-Garcia, Matilde
Publisher: name: Elsevier
Year: 2022

description:
Two-thirds of patients with mucopolysaccharidosis II (MPS II; Hunter syndrome) have cognitive impairment. This phase 2/3, randomized, controlled, open-label, multicenter study (NCT02055118) investigated the effects of intrathecally administered idursulfase-IT on cognitive function in patients with MPS II. Children older than 3 years with MPS II and mild-to-moderate cognitive impairment (assessed by Differential Ability Scales-II [DAS-II], General Conceptual Ability [GCA] score) who had tolerated intravenous idursulfase for at least 4 months were randomly assigned (2:1) to monthly idursulfase-IT 10 mg (n = 34) via an intrathecal drug delivery device (IDDD; or by lumbar puncture) or no idursulfase-IT treatment (n = 15) for 52 weeks. All patients continued to receive weekly intravenous idursulfase 0.5 mg/kg as standard of care. Of 49 randomized patients, 47 completed the study (two patients receiving idursulfase-IT discontinued). The primary endpoint (change from baseline in DAS-II GCA score at week 52 in a linear mixed-effects model for repeated measures analysis) was not met: although there was a smaller decrease in DAS-II GCA scores with idursulfase-IT than with no idursulfase-IT at week 52, this was not significant (least-squares mean treatment difference [95% confidence interval], 3.0 [-7.3, 13.3]; p = 0.5669). Changes from baseline in Vineland Adaptive Behavioral Scales-II Adaptive Behavior Composite scores at week 52 (key secondary endpoint) were similar in the idursulfase-IT (n = 31) and no idursulfase-IT (n = 14) groups. There were trends towards a potential positive effect of idursulfase-IT across DAS-II composite, cluster, and subtest scores, notably in patients younger than 6 years at baseline. In a post hoc analysis, there was a significant (p = 0.0174), clinically meaningful difference in change from baseline in DAS-II GCA scores at week 52 with idursulfase-IT (n = 13) versus no idursulfase-IT (n = 6) among those younger than 6 years with missense iduronate-2-sulfatase gene variants. Overall, idursulfase-IT reduced cerebrospinal glycosaminoglycan levels from baseline by 72.0% at week 52. Idursulfase-IT was generally well tolerated. These data suggest potential benefits of idursulfase-IT in the treatment of cognitive impairment in some patients with neuronopathic MPS II. After many years of extensive review and regulatory discussions, the data were found to be insufficient to meet the evidentiary standard to support regulatory filings.
OCTAVE Criteria, Version 2.0
Creators: name: Albert, Cecilia
name: Dorofee, Audrey J.
Publisher: name: Carnegie Mellon University
Year: 2001
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: Today, we rely on access to digital data that are accessible, dependable, and protected from misuse. Unfortunately, this need for accessible data also exposes organizations to a variety of new threats that can affect their information. The Operationally Critical Threat, Asset, and Vulnerability Evaluation (OCTAVE) enables organizations to understand and address their information security risks. OCTAVE is led by a small, interdisciplinary team of an organization's personnel and focuses on an organization's assets and the risks to those assets. It is a comprehensive, systematic, context-driven, and self-directed evaluation approach. The essential elements of the OCTAVE approach are embodied in a set of criteria that define the requirements for OCTAVE. This report describes the OCTAVE criteria. The goal of this report is to define a general approach for evaluating and managing information security risks. Organizations can then develop methods that are consistent with the OCTAVE criteria.
Reconstruction of scalar potentials in two-field cosmological models
Creators: name: Andrianov, Alexander A.
name: Cannata, Francesco
name: Kamenshchik, Alexander Y.
name: Regoli, Daniele
Publisher: name: arXiv
Year: 2007
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the procedure of the reconstruction of phantom-scalar field potentials in two-field cosmological models. It is shown that while in the one-field case the chosen cosmological evolution defines uniquely the form of the scalar potential, in the two-field case one has an infinite number of possibilities. The classification of a large class of possible potentials is presented and the dependence of cosmological dynamics on the choice of initial conditions is investigated qualitatively and numerically for two particular models.
description: final version, to appear in JCAP
Régimen jurídico de la unidad administrativa especial dentro de la organización del Estado y su incidencia en el regulador de las comunicaciones.
Creators: name: López Amarís, Efraín Armando
Publisher: name: Universidad Externado de Colombia. Departamento de Derecho de las Telecomunicaciones.
Year: 2022
Subjects: subject: Telecomunicaciones - Aspectos jurídicos - Colombia
subject: Tecnologías de la información y la comunicación - Aspectos jurídicos - Colombia
subject: Derecho comparado - Colombia
subject: Colombia - Administración pública - Aspectos jurídicos
subject: Regulación
subject: Independencia
subject: Autonomía
subject: Comunicaciones

description: La actividad de regulación ejercida por la Comisión de Regulación de Comunicaciones (CRC) presenta falencias en lo que a autonomía estatutaria e independencia funcional se refiere. Lo anterior, en razón a su encuadramiento como unidad administrativa especial, su pertenencia a la Administración Pública, así como a la composición y elección de sus miembros. Así las cosas, la propuesta final de esta tesis centra sus esfuerzos en proponer soluciones que intenten conjurar las problemáticas antes expuestas, reorganizando la CRC dentro de otra de las figuras de derecho administrativo como lo es la agencia, con un contenido normativo nuevo y reformando la composición, mecanismos de elección y periodos de los comisionados.
description: The regulatory activity carried out by the Communications Regulation Commission (CRC) has weaknesses in terms of statutory autonomy and functional independence. The foregoing, due to its framing as a special administrative unit, its membership in the Public Administration, as well as the composition and election of its members. In this vein, the final proposal of this thesis focuses its efforts on proposing solutions that try to remedy the problems previously exposed, reorganizing the CRC within another of the administrative law figures such as the agency, with a new normative content and amend the composition, election mechanisms and terms of commissioners.
Additional file 6 of Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults
Creators: name: Osuna-Prieto, Francisco J.
name: Martinez-Tellez, Borja
name: Ortiz-Alvarez, Lourdes
name: Di, Xinyu
name: Jurado-Fasoli, Lucas
name: Xu, Huiwen
name: Ceperuelo-Mallafré, Victoria
name: Núñez-Roa, Catalina
name: Kohler, Isabelle
name: Segura-Carretero, Antonio
name: García-Lario, José V.
name: Gil, Angel
name: Aguilera, Concepción M.
name: Llamas-Elvira, Jose M.
name: Rensen, Patrick C. N.
name: Vendrell, Joan
name: Ruiz, Jonatan R.
name: Fernández-Veledo, Sonia
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Additional file 6: Fig S1. Waterfall plot showing plasma succinate levels per individual (n=100). Each bar represents a single individual.
Exploring the Impact of the COVID-19 Pandemic on Youth Sport and Physical Activity Participation Trends
Creators: name: Teare, Georgia
name: Taks, Marijke
Publisher: name: My University
Year: 2021
Subjects: coronavirus
community sport
organized sport
non-organized sport
social ecology theory

description: The COVID-19 pandemic offers youth sport organizations the opportunity to anticipate consumer behaviour trends and proactively improve their program offerings for more satisfying experiences for consumers post-pandemic. This conceptual paper explores potential impacts of the COVID-19 pandemic on changing youth sport and physical activity preferences and trends to inform sport and physical activity providers. Drawing from social ecology theory, assumptions for future trends for youth sport and physical activity are presented. Three trends for youth sport and physical activity as a result of the COVID-19 pandemic are predicted: (1) youths’ preferences from organized to non-organized contexts become amplified; (2) reasons for participating in sport or any physical activity shift for youth as well as parents/guardians; (3) consumers reconceptualize value expectations from youth sport and physical activity organizations. The proposed assumptions need to be tested in future research. It is anticipated that sport organizations can respond to changing trends and preferences by innovating in three areas: (1) programming, (2) marketing, and (3) resource management. View Full-Text
The Weak Gravity Conjecture and Emergence from an Ultraviolet Cutoff
Creators: name: Heidenreich, Ben
name: Reece, Matthew
name: Rudelius, Tom
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study ultraviolet cutoffs associated with the Weak Gravity Conjecture (WGC) and Sublattice Weak Gravity Conjecture (sLWGC). There is a magnetic WGC cutoff at the energy scale $e G_N^{-1/2}$ with an associated sLWGC tower of charged particles. A more fundamental cutoff is the scale at which gravity becomes strong and field theory breaks down entirely. By clarifying the nature of the sLWGC for nonabelian gauge groups we derive a parametric upper bound on this strong gravity scale for arbitrary gauge theories. Intriguingly, we show that in theories approximately saturating the sLWGC, the scales at which loop corrections from the tower of charged particles to the gauge boson and graviton propagators become important are parametrically identical. This suggests a picture in which gauge fields emerge from the quantum gravity scale by integrating out a tower of charged matter fields. We derive a converse statement: if a gauge theory becomes strongly coupled at or below the quantum gravity scale, the WGC follows. We sketch some phenomenological consequences of the UV cutoffs we derive.
description: 50 pages, 5 figures. v2: references added, clarified remarks about Higgsing
Spatial amplitude and phase modulation using commercial twisted nematic LCDs
Creators: name: van Putten, E. G.
name: Vellekoop, I. M.
name: Mosk, A. P.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present a method for full spatial phase and amplitude control of a laser beam using a twisted nematic liquid crystal display combined with a spatial filter. By spatial filtering we combine four neighboring pixels into one superpixel. At each superpixel we are able to independently modulate the phase and the amplitude of light. We demonstrate experimentally the independent phase and amplitude modulation using this novel technique. Our technique does not impose special requirements on the spatial light modulator and allows precise control of fields even with imperfect modulators.
description: 10 pages, 6 figures
OCTAVE Catalog of Practices, Version 2.0
Creators: name: Albert, Cecilia
name: Dorofee, Audrey J.
name: Allen, Julia H.
Publisher: name: Carnegie Mellon University
Year: 2001
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: The Operationally Critical Threat, Asset, and Vulnerability Evaluation (OCTAVE) Method enables organizations to identify the risks to their most important assets and build mitigation plans to address those risks. OCTAVE uses three "catalogs" of information to maintain modularity and keep the method separate from specific technologies. One of these catalogs is the catalog of good security practices. It provides the means to measure an organization's current security practices and to build a strategy for improving its practices to protect its critical assets. The catalog of practices is divided into two types of practice—strategic and operational. The strategic practices focus on organizational issues at the policy level and provide good, general management practices. Operational practices focus on the technology-related issues dealing with how people use, interact with, and protect technology. This technical report describes how the catalog of practices is used in OCTAVE and describes the catalog in detail.
Additional file 8 of Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults
Creators: name: Osuna-Prieto, Francisco J.
name: Martinez-Tellez, Borja
name: Ortiz-Alvarez, Lourdes
name: Di, Xinyu
name: Jurado-Fasoli, Lucas
name: Xu, Huiwen
name: Ceperuelo-Mallafré, Victoria
name: Núñez-Roa, Catalina
name: Kohler, Isabelle
name: Segura-Carretero, Antonio
name: García-Lario, José V.
name: Gil, Angel
name: Aguilera, Concepción M.
name: Llamas-Elvira, Jose M.
name: Rensen, Patrick C. N.
name: Vendrell, Joan
name: Ruiz, Jonatan R.
name: Fernández-Veledo, Sonia
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Additional file 8: Fig. S3. Interaction network pathway analysis of circulating omega-3 and omega-6 oxylipins (n = 98)
Pure spin current transport in a SiGe alloy
Creators: name: Naito, T.
name: Yamada, M.
name: Tsukahara, M.
name: Yamada, S.
name: Sawano, K.
name: Hamaya, K.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Using four-terminal nonlocal magnetoresistance measurements in lateral spin-valve devices with Si$_{\rm 0.1}$Ge$_{\rm 0.9}$, we study pure spin current transport in a degenerate SiGe alloy ($n \sim$ 5.0 $\times$ 10$^{18}$ cm$^{-3}$). Clear nonlocal spin-valve signals and Hanle-effect curves, indicating generation, manipulation, and detection of pure spin currents, are observed. The spin diffusion length and spin lifetime of the Si$_{\rm 0.1}$Ge$_{\rm 0.9}$ layer at low temperatures are reliably estimated to be $\sim$ 0.5 $μ$m and $\sim$ 0.2 ns, respectively. This study demonstrates the possibility of exploring physics and developing spintronic applications using SiGe alloys.
description: 5 pages, 3 figures
Beyond coverage: Rural-urban disparities in the timeliness of childhood vaccinations in Tanzania
Creators: name: Ghosh, Suvomita Happy
name: Baumgartner, Joy Noel
name: Mfinanga, Sayoki Godfrey
name: Hair, Nicole L
name: Yelverton, Valerie
name: Vasudevan, Lavanya
name: Ostermann, Jan
name: Ngadaya, Esther
Publisher: name: Elsevier
Year: 2022

description:
BACKGROUND: Timely vaccination maximizes efficacy for preventing infectious diseases. In the absence of national vaccination registries, representative sample survey data hold vital information on vaccination coverage and timeliness. This study characterizes vaccination coverage and timeliness in Tanzania and provides an analytic template to inform contextually relevant interventions and evaluate immunization programs. METHODS: Cross-sectional data on 6,092 children under age 3 from the 2015-16 Tanzania Demographic and Health Survey were used to examine coverage and timeliness for 14 vaccine doses recommended in the first year of life. The Kaplan-Meier method was used to model time to vaccination. Cox proportional hazard models were used to examine factors associated with timely vaccination. RESULTS: Substantial rural-urban disparities in vaccination coverage and timeliness were observed for all vaccines. Across 14 recommended doses, documented coverage ranged from 52 % to 79 %. Median vaccination delays lasted up to 35 days; gaps were larger among rural than urban children and for later doses in vaccine series. Among rural children, median delays exceeded 35 days for the 3rd doses of the polio, pentavalent, and pneumococcal vaccines. Median delays among urban children were < 21 days for all doses. Among rural and urban children, lower maternal education and delivery at home were associated with increased risk of delayed vaccination. In rural settings, less household wealth and greater distance to a health facility were also associated with increased risk of delayed vaccination. DISCUSSION: This study highlights persistent gaps in uptake and timeliness of childhood vaccinations in Tanzania and substantial rural-urban disparities. While the results provide an informative situation assessment and outline strategies for identifying unvaccinated children, a national electronic registry is critical for comprehensive assessments of the performance of vaccination programs. The timeliness measure employed in this study-the amount of time children are un- or undervaccinated-may serve as a sensitive performance metric for these programs.
Dexamethasone versus prednisone for children receiving asthma treatment in the paediatric inpatient population: protocol for a feasibility randomised controlled trial
Creators: name: Pound, Catherine M
name: McDonald, Jaime
name: Tang, Ken
name: Seidman, Gillian
name: Jetty, Radha
name: Zaidi, Sarah
name: Plint, Amy C
Publisher: name: My University
Year: 2018
Subjects: asthma
dexamethasone
inpatient
paediatrics
prednisone
randomised controlled trial

description: Asthma exacerbations are a leading cause of paediatric hospitalisations. Corticosteroids are key in the treatment of asthma exacerbations. Most current corticosteroids treatment regimens for children admitted with asthma exacerbation consist of a 5-day course of prednisone or prednisolone. However, these medications are associated with poor taste and significant vomiting, resulting in poor compliance with the treatment course. While some centres already use a short course of dexamethasone for treating children hospitalised with asthma, there is no evidence to support this practice in the inpatient population.
N.N.–nomen nescio: identidades negadas en los manicomios
Creators: name: Gorla, Paola Laura
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Salud mental - Aspectos jurídicos
subject: Atención hospitalaria psiquiátrica - Aspectos jurídicos
subject: Servicios de salud mental - Aspectos jurídicos
subject: Declaración de Caracas
subject: Biopolítica
subject: Atención psiquiátrica
subject: Derechos civiles de los enfermos mentales
subject: El infarto del alma
subject: Manicomio
subject: Ley Basaglia
subject: N.N. nomen nescio

description: Objetivo del presente estudio es el de explorar la revolución en materia de derechos y salud mental que supuso la llamada Declaración de Caracas (1990), firmada por la OMS y la OPS. Detectaremos los factores prodrómicos que llevaron a su redacción, así como su impacto en la reforma de la salud mental chilena mediante el análisis de los testimonios recogidos en El infarto del alma de Eltit y Errázuriz, donde se combinan materiales literarios y documentales que, en su conjunto, van a componer el punto de vista del paciente. En particular, nos detendremos en el caso de los pacientes sin nombre (N.N.).
description: The aim of this study is to explore the revolution in the matter of psychiatric treatment protocols represented by the so-called Caracas Declaration of 1990, drafted by the WHO and the PAHO. We will detect the prodromal factors that led to its drafting, as well as its impact on the Chilean mental health reform by analysing the testimonies collected in Eltit and Errázuriz’s book El infarto del alma. It combines both literary and documentary materials that teem with evidence, images, feelings and clues, altogether composing an internal point of view: the patient’s perspective. In particular, we will focus on the case of the unnamed patients (N.N.).
Carnet nº 18, commencé à Canton (p. 23)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 10-1-1931
Object-Oriented Software Measures
Creators: name: Archer, Clark
name: Stinson, Michael
Publisher: name: Carnegie Mellon University
Year: 1995
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: This paper provides an overview of the merging of a paradigm and a process, the object-oriented paradigm and the software product measurement process. A taxonomy of object-oriented software measures is created, and existing object-oriented software measures are enumerated, evaluated, and placed in taxa. This report includes an extensive bibliography of the current object-oriented measures that apply to the design and implementation phases of a software project. Examples of computation of representative measures are included.
title: 19_F_ROUSSET_LaLuneDeMiel_FR_GAD
Creators: name: Rousset, Pierre
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: PuppetPlays
subject: Horizon 2020
subject: Plassard, Didier
subject: Guignol (personnage fictif)
subject: PuppetPlays
subject: Horizon 2020
subject: Plassard, Didider
subject: Guignol (personnage fictif)

description: MAM - Musée des Arts de la Marionnette (Musée Gadagne). B86/R D98. Acquis de Durafour, 69 rue Cuvier, Lyon, le 1er mai 1927.
Tribulations conjugales en 4 tableaux. Cahier manuscrit. Le 5 avril 1894.

Numérisé dans le cadre du projet ERC PuppetPlays, financé par le Programme de recherche et d'innovation Horizon 2020 de l'Union Européenne (Grant Agreement 835193).
description: Digitized by the ERC project PuppetPlays, receiving funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement ERC 835193.
Evidence for high excitation energy resonances in the 7 alpha disassembly of $^{28}$Si
Creators: name: Cao, X. G.
name: Kim, E. J.
name: Schmidt, K.
name: Hagel, K.
name: Barbui, M.
name: Gauthier, J.
name: Wuenschel, S.
name: Giuliani, G.
name: Rodriguez, M. R. D.
name: Kowalski, S.
name: Zheng, H.
name: Huang, M.
name: Bonasera, A.
name: Wada, R.
name: Zhang, G. Q.
name: Wong, C. Y.
name: Staszczak, A.
name: Ren, Z. X.
name: Wang, Y. K.
name: Zhang, S. Q.
name: Meng, J.
name: Natowitz, J. B.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The excitation function for the 7 alpha de-excitation of $^{28}$Si nuclei excited to high excitation energies in the collisions of 35 MeV/nucleon $^{28}$Si with $^{12}$C reveals resonance structures that may indicate the population of high spin toroidal isomers such as those predicted by a number of recent theoretical calculations. This interpretation is supported by extended theoretical analyses.
description: 11 pages, 5 figures
Notes on Applications of the SQL ADA Module Description Language (SAMeDL)
Creators: name: Chastek, Gary J.
name: Graham, Mark H.
name: Zelesnik, Gregory
Publisher: name: Carnegie Mellon University
Year: 1991
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: The SQL ADA Module Description Language (SAMeDL) is a language for describing information services to be provided to ADA application programs by SQL database management systems. This report shows how the SAMeDL can be adapted and extended to provide services to applications needing advanced features (e.g., dynamic SQL, or using non-ANSI standard data types (decimal, date) or having other unusual requirements. It also contains short descriptions of some implementation details.
Examining the relationship between race-related stressors and post-traumatic stress disorder among African American male Vietnam veterans
Creators: name: Williams, David Zamon
Publisher: name: Washington State University
Year: 2007
Subjects: Vietnam War, 1961-1975 -- Veterans -- Mental health -- Racial analysis

description: It is estimated that 1,700,000 Vietnam War veterans have experienced "clinically
description: serious stress reaction symptoms" (National Center for Post Traumatic Stress Disorder,
description: 2005). Of this figure, all ethnic minorities (except for Japanese) reported the greatest life
description: time prevalence of posttraumatic stress disorder (PTSD) compared to Whites (Kulka,
description: Schlenger, Fairbank, Hough, Jordan, Marmar, & Weiss, 1990). The National Vietnam
description: Veterans Readjustment Study (NVVRS) found that African American Vietnam War
description: veterans had greater exposure to war stressors and had more predisposing factors than
description: Whites (Kulka et al., 1990). The Race-Related Stressor Scale (RRSS) is the only
description: instrument that exists to measure race-related stressors that contribute uniquely and
description: substantially to PTSD symptoms and generalized psychiatric distress in an ethnic
description: minority Vietnam Veteran sample. A previous study found that race-related stressors
description: account for a significant proportion of the variance in PTSD symptoms of Asian
description: American Vietnam Veterans (Loo, Fairbank, Scurfield, Ruch, King, Adams, & Chemtob,
description: 2001). Although African American Vietnam War veterans are one of the most frequently
description: studied samples, no instrument exists to measure race-related exposure accounting for
description: their PTSD symptoms.
description: There are two purposes of this study: Primary is to adapt and validate the RRSS
description: using an African American Vietnam Veteran sample, and secondary is to examine the
description: amount of variability the adapted RRSS accounts for in PTSD and generalized
description: psychiatric distress symptoms. This new measure will be called the Vietnam Racial
description: Stressor Scale for African American Vietnam Veterans (VRSS). The construct validity
description: of the adapted RRSS will be examined by investigating the relationship between the
description: VRSS, PTSD, and general psychiatric distress symptoms, controlling for military rank
description: and exposure to combat. The temporal stability of the VRSS will be assessed using
description: Cronbach’s Alpha method. Results of the temporal stability of the VRSS will be
description: compared to Loo et al., (2001) RRSS temporal stability for Asian American Vietnam
description: War veterans. A general discussion of the temporal stability comparisons between the
description: RRSS and its adaptations will suggest the generalizability of the RRSS with other
description: Vietnam War veteran ethnic groups.
title: Bienestar subjetivo como política pública : una apuesta por el desarrollo integral de Cundinamarca
title: Estudio de caso sobre el agendamiento de la política de felicidad y bienestar subjetivo (PPFyBS) en el departamento de Cundinamarca (2015-2019)
titleType: AlternativeTitle
Creators: name: García Loaiza, María Emilia
name: Guayacán Trujillo, Daniela Alejandra
Publisher: name: Universidad Externado de Colombia
Year: 2022
Subjects: subject: Indicadores económicos
subject: Sistema de las Naciones Unidas
subject: Política pública
subject: Bienestar subjetivo
subject: Felicidad
subject: Desarrollo de capacidades
subject: Políticas públicas

description: Esta investigación se realiza con el propósito de conocer cuáles fueron las prioridades políticas e institucionales y el concepto de desarrollo implícito en ellas, que permitió el proceso de agendamiento de la Política Pública de Felicidad y Bienestar Subjetivo en Cundinamarca. Para ello, se presenta en un primer momento una aproximación conceptual al bienestar subjetivo y a las políticas públicas entendiendo estos como un nuevo elemento constitutivo del desarrollo. Posteriormente, se describen los indicadores convencionales de medición de felicidad y bienestar, para luego explorar algunas alternativas a la tradicional visión economicista. Más adelante, se relacionan las teorías y marcos de análisis para comprender el proceso de agendamiento de una política pública; y se exponen las etapas y escenarios de la PPFBS de Cundinamarca. Posteriormente, se expone la metodología de investigación y se da paso al análisis de las fuentes primarias y secundarias. Se realiza una profundización en el proceso de agendamiento de la PPFBS de Cundinamarca y finalmente, se presentan las conclusiones de la investigación, brindando elementos que pueden ser considerados en otros procesos de agendamiento de políticas públicas de felicidad, en pro de mejorar la calidad de vida de las personas y el desarrollo del territorio.
description: This research is developed with the purpose of understanding which was the concept of development, used in the political and institutional agenda that allowed the generation of the "Public policy of happiness and subjective wellbeing in Cundinamarca". First, concepts of subjective wellbeing and public policies are clarified and understood as crucial for society development. Then, indicators for happiness and wellbeing are described; followed by sorne insights regarding the traditional economic view on this matter. Later, theories and data are analyzed to clarify how a public policy is settled and PPFBS stages and scenarios are explained. Next, research methodology is described, and primary and secondary sources are analyzed. Subsequently, we discuss in depth the process of the PPFBS agenda of the department of Cundinamarca and research conclusions are provided, these might be considered in other happiness public policies agendas aimed to improve society's life quality and territorial development.
Visible Minority Wage Gaps for Highly Educated Immigrant and Canadian-born Workers with Canadian Degrees
Creators: name: Yu, Shengyi
Publisher: name: My University
Year: 2018

description: Canada is an important immigration country and more and more residents belong to different visible minority groups. This paper uses the 2011 National Household Survey to investigate the wage gap between visible minority groups and non-visible minority workers, focusing on highly educated immigrants and non-immigrants. All individuals in the sample have at least a Canadian bachelor degree. The visible minority workers are divided into the categories of Black, Chinese, South Asian, and Rest of the World. The paper finds that on average, immigrants earn less than non-immigrants. Comparing the genders, the visible minority wage gaps are smaller for females than for males. Among the visible minority groups, Black males are the group that suffers the most from wage disadvantage, regardless of their immigration status and the number of years since immigration. For the other visible minority groups and for the females, there are greater wage disadvantages among immigrants than among non-immigrants.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0441
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0441, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0441, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Research Software Directory - A content management system tailored to research software
Creators: name: Spaaks, Jurriaan H.
Publisher: name: Zenodo
Year: 2019
Subjects: research software
CRIS
content management system
software citation
software discovery
software metadata

description: This presentation introduces the Research Software Directory, a content management system tailored to research software. The system has been designed to publish metadata about software packages as easily readable, well-structured web pages, such that web page visitors can quickly judge whether the software advertised in the content management system will help them address their problems. Furthermore, the system aims to minimize the burden that is placed on content providers, i.e. the developers of a given software package. This minimization is realized by harvesting whatever data is already available from other systems such as Zotero, GitHub, and Zenodo. Such automated integration helps with keeping the Research Software Directory contents up to date and accurate. The Research Software Directory uses recent advances in machine-readable citation metadata to disseminate software reference manager files in BibTex, EndNote, and RIS formats, while promoting discovery by search engines through the use of schema.org metadata embedded within individual web pages.
Network Survivability Analysis Using Easel
Creators: name: Christie, Alan M.
Publisher: name: Carnegie Mellon University
Year: 2002
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: The survivability of large, complex networks such as the Internet is an increasing concern, but such networks are difficult to analyze because they are topologically complex, highly non-linear in their responses, and inherently unbounded (i.e., no node in the network can have global knowledge). To support survivability research, this report will describe how to develop statistically valid networks for analysis and, as an example of their use, applying them to the simulation of virus propagation. It will illustrate the construction of network topologies with GENeSIS, a program written in the programming language Easel. The report will also summarize ongoing significant work in this area of research and give readers insight into how information or artifacts flow through networks and how networks respond to major disruptions.