cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD)
Creators: name: Upadhyay, Priya
name: Wu, Ching-Wen
name: Pham, Alexa
name: Zeki, Amir A.
name: Royer, Christopher M.
name: Kodavanti, Urmila P.
name: Takeuchi, Minoru
name: Bayram, Hasan
name: Pinkerton, Kent E.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, and its global health burden is increasing. COPD is characterized by emphysema, mucus hypersecretion, and persistent lung inflammation, and clinically by chronic airflow obstruction and symptoms of dyspnea, cough, and fatigue in patients. A cluster of pathologies including chronic bronchitis, emphysema, asthma, and cardiovascular disease in the form of hypertension and atherosclerosis variably coexist in COPD patients. Underlying causes for COPD include primarily tobacco use but may also be driven by exposure to air pollutants, biomass burning, and workplace related fumes and chemicals. While no single animal model might mimic all features of human COPD, a wide variety of published models have collectively helped to improve our understanding of disease processes involved in the genesis and persistence of COPD. In this review, the pathogenesis and associated risk factors of COPD are examined in different mammalian models of the disease. Each animal model included in this review is exclusively created by tobacco smoke (TS) exposure. As animal models continue to aid in defining the pathobiological mechanisms of and possible novel therapeutic interventions for COPD, the advantages and disadvantages of each animal model are discussed.
Transmission function properties for multi-layered structures: Application to super-resolution
Creators: name: Mattiucci, Nadia
name: D'Aguanno, Giuseppe
name: Scalora, Michael
name: Bloemer, Mark J.
name: Sibilia, Concita
Publisher: name: arXiv
Year: 2009
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We discuss the properties of the transmission function in the k-space for a generic multi-layered structure. In particular we analytically demonstrate that a transmission greater than one in the evanescent spectrum (amplification of the evanescent modes) can be directly linked to the guided modes supported by the structure. Moreover we show that the slope of the phase of the transmission function in the propagating spectrum is inversely proportional to the ability of the structure to compensate the diffraction of the propagating modes. We apply these findings to discuss several examples where super-resolution is achieved thanks to the simultaneous availability of the amplification of the evanescent modes and the diffraction compensation of the propagating modes.
Mode of action of monuron (3- (4-chlorophenyl) -1, 1- dimethylurea.
Creators: name: Baldwin, Richard William Ward
Publisher: name: University of British Columbia
Year: 2011

description: The herbicidal action of monuron, 3-(4-chlorophenyl)-1, 1-dimethylurea, cannot be completely realized until the mode of action is fully understood. It is believed that the primary site of action is in the photosynthetic complex. The present investigations included: The study of the effects of monuron on some enzyme systems, greenhouse studies on the effects of monuron on the morphology of potato plants, field studies on the yield of barley treated with the substituted urea herbicides, the residual effects of the substituted urea herbicides applied to soil, the effects of monuron and the interaction of monuron and vitamin K on the rate of the photolysis of water by isolated chloroplasts. The photolysis of water was followed by observing changes in potential of a potasium ferricyanide solution containing isolated chloroplasts. Monuron inhibited the protease enzyme system and stimulated the lipase enzyme system. This herbicide reduced the total weight of potato tubers per plant, the root to top ratio and the total weight of barley grain per acre. The top growth of potato plants and the bushel weight of barley were increased with monuron applications. 1 X 10¯⁷ moles of monuron reduced the rate of the Hill reaction by more than 50%. The data presented did not confirm vitamin K as a cofactor in the Hill reaction.
Nanobiocatalysts with inbuilt cofactor recycling for oxidoreductase catalysis in organic solvents
Creators: name: Sahlin, Jenny
name: Wu, Congyu
name: Buscemi, Andrea
name: Schärer, Claude
name: Nazemi, Seyed Amirabbas
name: S. K., Rejaul
name: Herrera-Reinoza, Nataly
name: Jung, Thomas A.
name: Shahgaldian, Patrick
Publisher: name: Royal Society of Chemistry
Year: 2023
Subjects: subject: 500 - Naturwissenschaften und Mathematik

description: The major stumbling block in the implementation of oxidoreductase enzymes in continuous processes is their stark dependence on costly cofactors that are insoluble in organic solvents. We describe a chemical strategy that allows producing nanobiocatalysts, based on an oxidoreductase enzyme, that performs biocatalytic reactions in hydrophobic organic solvents without external cofactors. The chemical design relies on the use of a silica-based carrier nanoparticle, of which the porosity can be exploited to create an aqueous reservoir containing the cofactor. The nanoparticle core, possessing radial-centred pore channels, serves as a cofactor reservoir. It is further covered with a layer of reduced porosity. This layer serves as a support for the immobilisation of the selected enzyme yet allowing the diffusion of the cofactor from the nanoparticle core. The immobilised enzyme is, in turn, shielded by an organosilica layer of controlled thickness fully covering the enzyme. Such produced nanobiocatalysts are shown to catalyse the reduction of a series of relevant ketones into the corresponding secondary alcohols, also in a continuous flow fashion. © 2023 RSC.
Settimana dell’astronomia, lunedì si parte
Creators: Gianluigi Filippelli
Publisher: name: Media Inaf
Year: 2018

Dal 16 al 21 aprile 2018 arriva la diciannovesima Settimana nazionale dell’astronomia, organizzata dalla Sait in collaborazione con l’Inaf. Scopriamo insieme il ricco programma di iniziative e proposte – per le scuole e non solo – sparse sul territorio nazionale
How technical innovations may help to prevent drug shortages in switzerland
Creators: name: Gygax, Daniel
name: Eigenmann, Kaspar
name: Suter, Christian
name: Hürzeler Müller, Marianne
name: Mahmoud, Ahmed
name: Mosbacher, Johannes
name: Pöllinger, Norbert
Publisher: name: Schweizerische Chemische Gesellschaft
Year: 2023
Subjects: subject: Automation of chemical synthesis
subject: Micropellet formulation
subject: On-demand production
subject: Personalized healthcare
subject: 500 - Naturwissenschaften und Mathematik

description: In this work, we investigated the technical feasibility of 'on-demand' production of selected drugs to cover their demand for a time window of 90 days. We focused on two sub-processes 'automated chemical synthesis' and 'formulation in micropellets'  to enable personalized dosing. The production of drugs 'on-demand' is challenging, important, but also attractive. Switzerland could thus gain access to an additional instrument for increasing resilience for supply-critical drugs. The biggest challenge in the case study presented here is the scalability of automated chemical synthesis and the application range of micropellet formulations.
Dynamic vertical green walls & shading systems integration to enhance energy efficiency & thermal comfort: A case of educational building skin retrofit in a Mediterranean city
Creators: name: Elzayat, Menna
Publisher: name: Zenodo
Year: 2025
Subjects: climate change; intelligent adaptive building skin; Quality of the indoor climate, Dynamic vertical green walls (DVGS)
green walls
building skin retrofit
thermal comfort

description: Since 1900, global temperatures have increased, with the average annual temperature along the Mediterranean coast rising from 20°C to 24°C. The outdoor climate has a crucial function in defining indoor environmental quality (IEQ) and overall performance of the building, especially in educational buildings. Given the global focus on energy consumption, climate change, and urban environments, dynamic vertical greening systems (DVGS) have gained significant attention in architectural and design research. This paper explores the incorporation of movable green walls into building facades to enhance urban ecosystems. In contrast to conventional passive green walls, active green walls present a dynamic visual appeal and deliver multiple advantages, such as shading, passive cooling, and avenues for personal expression in densely populated urban settings. The primary objective of this paper is to assess the shading and effectiveness of energy of Dynamic Vertical Green Systems (DVGS) in buildings located in hot climates particularly in educational buildings, to refine their design as an outdoor architectural feature. This paper proposes dynamic vertical green systems (DVGS) as convenient solution for elevated temperatures in the mediterranean climate due to climate change.
title: ÐÑÐµÐ½ÐºÐ° ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð±Ð°Ð½ÐºÐ°: ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ Ð¸ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ²Ð°Ð½Ð¾Ð²Ð°, ÐÐ»ÑÐ³Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð±Ð°Ð½Ðº
ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ
ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ Ð¾ÑÐµÐ½ÐºÐ¸
ÐºÐ°ÑÐµÑÑÐ²Ð¾ Ð°ÐºÑÐ¸Ð²Ð¾Ð²
ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÐµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ ÐÐÐ Â«Ð¡Ð±ÐµÑÐ±Ð°Ð½Ðº Ð Ð¾ÑÑÐ¸Ð¸Â».
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Sphere, due dischi per tre stelle
Creators: Rossella Spiga
Publisher: name: Media Inaf
Year: 2018

Un disco circumstellare è stato scoperto attorno a una stella nana rossa, che a sua volta è legata gravitazionalmente a un'altra coppia di stelle, dotata di un anello in gran parte composto da gas. Il merito è del team di ricercatori guidato da Elena Sissa dell'Inaf di Padova e delle immagini prodotte dallo strumento Sphere installato al Vlt dell'Eso
Test-retest reliability and agreement of the Numerical Pain Rating Scale and Visual Analogue Scale in a population with low back pain
Creators: name: Devonshire, Jack
name: Jones, Matthew
name: Cashin, Aidan
name: Williams, Sam A
name: Wewege, Michael
name: McAuley, James
name: Hansford, Harrison
name: Ferraro, Michael C
name: Sharma, Saurab
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Life Sciences

description: Clinimetric research f commonly used pain intensity outcome measurement scales in low back pain.
Constructions of E_{vc} and E_{fbc} for groups acting on CAT(0) spaces
Creators: name: Farley, Daniel
Publisher: name: arXiv
Year: 2009
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55N15, 18F25

description: If G is a group acting properly by semisimple isometries on a proper CAT(0) space X, then we build models for the classifying spaces E_{vc} and E_{fbc} under the additional assumption that the action of G has a well-behaved collection of axes in X. (This hypothesis is described in the paper.) We conjecture that the latter hypothesis is satisfied in a large range of cases. Our classifying spaces resemble those created by Connolly, Fehrman, and Hartglass for crystallographic groups G.
description: 16 pages, no figures
Quelle giovani stelle ammantate di polvere
Creators: Redazione Eso
Publisher: name: Media Inaf
Year: 2018

Nuove immagini ottenute in Cile dall’Eso stanno rivelando con un dettaglio mai raggiunto finora alcuni dischi di polvere che circondano giovani stelle vicine: mostrano una bizzarra varietà di forme, dimensioni e strutture, tra cui il probabile effetto dei pianeti che si stanno ancora formando
Phase-Only Planar Antenna Array Synthesis with Fuzzy Genetic Algorithms
Creators: name: Kadri, Boufeldja
name: Boussahla, Miloud
name: Bendimerad, Fethi Tarik
Publisher: name: arXiv
Year: 2010
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: This paper describes a new method for the synthesis of planar antenna arrays using fuzzy genetic algorithms (FGAs) by optimizing phase excitation coefficients to best meet a desired radiation pattern. We present the application of a rigorous optimization technique based on fuzzy genetic algorithms (FGAs), the optimizing algorithm is obtained by adjusting control parameters of a standard version of genetic algorithm (SGAs) using a fuzzy controller (FLC) depending on the best individual fitness and the population diversity measurements (PDM). The presented optimization algorithms were previously checked on specific mathematical test function and show their superior capabilities with respect to the standard version (SGAs). A planar array with rectangular cells using a probe feed is considered. Included example using FGA demonstrates the good agreement between the desired and calculated radiation patterns than those obtained by a SGA.
description: International Journal of Computer Science Issues, IJCSI, Vol. 7, Issue 1, No. 2, January 2010, http://ijcsi.org/articles/Phase-Only-Planar-Antenna-Array-Synthesis-with-Fuzzy-Genetic-Algorithms.php
QSAR classification model for diverse series of antifungal agents based on binary coyote optimization algorithm
Creators: name: Al-Fakih, A.M.
name: Qasim, M.K.
name: Algamal, Z.Y.
name: Alharthi, A.M.
name: Zainal-Abidin, M.H.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: One of the recently developed metaheuristic algorithms, the coyote optimization algorithm (COA), has shown to perform better in a number of difficult optimization tasks. The binary form, BCOA, is used in this study as a solution to the descriptor selection issue in classifying diverse antifungal series. Z-shape transfer functions (ZTF) are evaluated to verify their efficiency in improving BCOA performance in QSAR classification based on classification accuracy (CA), the geometric mean of sensitivity and specificity (G-mean), and the area under the curve (AUC). The Kruskal-Wallis test is also applied to show the statistical differences between the functions. The efficacy of the best suggested transfer function, ZTF4, is further assessed by comparing it to the most recent binary algorithms. The results prove that ZTF, especially ZTF4, significantly improves the performance of the original BCOA. The ZTF4 function yields the best CA and G-mean of 99.03% and 0.992%, respectively. It shows the fastest convergence behaviour compared to other binary algorithms. It takes the fewest iterations to reach high classification performance and selects the fewest descriptors. In conclusion, the obtained results indicate the ability of the ZTF4-based BCOA to find the smallest subset of descriptors while maintaining the best classification accuracy performance.
Un calamaro alla ricerca della materia oscura
Creators: Alberto Laratro
Publisher: name: Media Inaf
Year: 2018

È un amplificatore Squid, un dispositivo superconduttore a interferenza quantistica. Grande circa un millimetro quadrato e raffreddato a temperature prossime allo zero assoluto, sarà utilizzato nel rivelatore Admx per intercettare i deboli segnali che dovrebbero venire prodotti dagli assioni nel caso in cui si convertano in fotoni a microonde
title: Ð aÐ·paÐ±oÑÐºa peÐºoÐ¼eÐ½Ð´aÑÐ¸Ð¹ Ð¿o Ð¿ocÑpoeÐ½Ð¸Ñ Ð¸ paÐ·Ð²Ð¸ÑÐ¸Ñ ÑÑÑeÐºÑÐ¸Ð²Ð½oÐ¹ cÐ¸cÑeÐ¼Ñ Ð±Ð¸Ð·Ð½ec-ÐºoÐ¼Ð¼ÑÐ½Ð¸ÐºaÑÐ¸Ð¹ Ð² ÐºoÐ¼Ð¿aÐ½Ð¸Ð¸ Â«Au Pont RougeÂ» Ð½a ocÐ½oÐ²e Ð²Ð½eÐ´peÐ½Ð¸Ñ ÑÐ»eÐºÑpoÐ½Ð½oÐ³o Ð´oÐºÑÐ¼eÐ½ÑooÐ±opoÑaÂ»
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð½, ÐÐ°Ð»ÐµÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð±Ð¸Ð·Ð½ec-ÐºoÐ¼Ð¼ÑÐ½Ð¸ÐºaÑÐ¸Ð¸
Ð´oÐºÑÐ¼eÐ½ÑooÐ±opoÑ
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description: OÐ±ÑeÐºÑoÐ¼ Ð¸ccÐ»eÐ´oÐ²aÐ½Ð¸Ñ ÑÐ²Ð»ÑeÑcÑ ÑÐ½Ð¸Ð²epÐ¼aÐ³ Â«Au Pont RougeÂ».
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title: Ð ÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ Ð²ÑÐ±Ð¾ÑÑ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ½ÐµÑÐ³Ð¾ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ (Ð½Ð° ÑÑÐ°Ð¿Ðµ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¶Ð¸Ð»ÑÑ Ð·Ð´Ð°Ð½Ð¸Ð¹)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
Creators: name: Ð¯ÑÐ¸Ð½ÑÐºÐ°Ñ, Ð¯Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÐÐ¸Ð»ÑÐµ Ð·Ð´Ð°Ð½Ð¸Ñ
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description: ÐÐµÑÐ²Ð°Ñ Ð³Ð»Ð°Ð²Ð° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸ Ð¿ÑÐ°Ð²Ð¾Ð²ÑÑ Ð¾ÑÐ½Ð¾Ð² ÑÐ½ÐµÑÐ³Ð¾ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¸ ÑÐ½ÐµÑÐ³Ð¾ÑÐ±ÐµÑÐµÐ¶ÐµÐ½Ð¸Ñ Ð² ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ðµ. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ½ÐµÑÐ³Ð¾ÑÐ±ÐµÑÐµÐ³Ð°ÑÑÐ¸Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ Ð¸ Ð¸Ð½Ð¶ÐµÐ½ÐµÑÐ½ÑÑ ÑÐµÑÐµÐ½Ð¸Ð¹ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð° Ð¶Ð¸Ð»ÑÑ Ð·Ð´Ð°Ð½Ð¸Ð¹. ÐÐ¾ÐºÐ°Ð·Ð°Ð½Ð° Ð·Ð½Ð°ÑÐ¸Ð¼Ð¾ÑÑÑ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ½ÐµÑÐ³Ð¾ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð·Ð´Ð°Ð½Ð¸Ð¹ Ð¿ÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ð¸ Ð¶Ð¸Ð»ÑÑ Ð·Ð´Ð°Ð½Ð¸Ð¹. Ð ÑÑÐµÑÑÐµÐ¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑÑ Ð¾ÑÐµÐ½ÐºÐ° ÐºÐ»Ð°ÑÑÐ° Ð¿ÑÐµÐ´Ð²Ð°ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ ÑÑÐ¾Ð²Ð½Ñ ÑÐ½ÐµÑÐ³Ð¾ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¶Ð¸Ð»Ð¾Ð³Ð¾ Ð·Ð´Ð°Ð½Ð¸Ñ, ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ Ð²ÑÐ±Ð¾ÑÑ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ½ÐµÑÐ³Ð¾ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð½Ð° ÑÑÐ°Ð¿Ðµ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¶Ð¸Ð»ÑÑ Ð·Ð´Ð°Ð½Ð¸Ð¹.
Modelling galaxy stellar mass evolution from z~0.8 to today
Creators: name: Wang, Lan
name: Jing, Y. P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We apply the empirical method built for z=0 in the previous work of Wang et al. to a higher redshift, to link galaxy stellar mass directly with its hosting dark matter halo mass at z~0.8. The relation of the galaxy stellar mass and the host halo mass M_infall is constrained by fitting both the stellar mass function and the correlation functions at different stellar mass intervals of the VVDS observation, where M_infall is the mass of the hosting halo at the time when the galaxy was last the central galaxy. We find that for low mass haloes, their residing central galaxies are less massive at high redshift than those at low redshift. For high mass haloes, central galaxies in these haloes at high redshift are a bit more massive than the galaxies at low redshift. Satellite galaxies are less massive at earlier times, for any given mass of hosting haloes. Fitting both the SDSS and VVDS observations simultaneously, we also propose a unified model of the M_stars-M_infall relation, which describes the evolution of central galaxy mass as a function of time. The stellar mass of a satellite galaxy is determined by the same M_stars-M_infall relation of central galaxies at the time when the galaxy is accreted. With these models, we study the amount of galaxy stellar mass increased from z~0.8 to the present day through galaxy mergers and star formation. Low mass galaxies gain their stellar masses from z~0.8 to z=0 mainly through star formation. For galaxies of higher mass, the increase of stellar mass solely through mergers from z=0.8 can make the massive galaxies a factor ~2 larger than observed at z=0. We can also predict stellar mass functions of redshifts up to z~3, and the results are consistent with the latest observations.
description: 12 pages, 10 figures, accepted for publication in MNRAS
title: ÐÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ Ð´Ð»Ñ ÑÐ¾Ð´Ð¸ÑÐµÐ»ÐµÐ¹ Ð²Ð¾ÑÐ¿Ð¸ÑÐ°Ð½Ð½Ð¸ÐºÐ¾Ð² Ð´ÐµÑÑÐºÐ¾Ð³Ð¾ ÑÐ°Ð´Ð° Ð¿ÑÐ¸ ÑÐºÐ¾Ð»Ðµ â 15 ÐÐ°ÑÐ¸Ð»ÐµÐ¾ÑÑÑÐ¾Ð²ÑÐºÐ¾Ð³Ð¾ Ñ-Ð½Ð° Ð³. Ð¡Ð°Ð½ÐºÑ ÐÐµÑÐµÑÐ±ÑÑÐ³Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÑÐ´Ð°ÑÑ, ÐÐ°ÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: it-ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸
Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ
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description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ñ ÑÐµÐ»ÑÑ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð»Ñ ÑÐ¾Ð´Ð¸ÑÐµÐ»ÐµÐ¹ Ð²Ð¾ÑÐ¿Ð¸ÑÐ°Ð½Ð½Ð¸ÐºÐ¾Ð² Ð´ÐµÑÑÐºÐ¾Ð³Ð¾ ÑÐ°Ð´Ð° Ð¿ÑÐ¸ ÑÐºÐ¾Ð»Ðµ â15 ÐÐ°ÑÐ¸Ð»ÐµÐ¾ÑÑÑÐ¾Ð²ÑÐºÐ¾Ð³Ð¾ ÑÐ°Ð¹Ð¾Ð½Ð°, Ñ ÑÐµÐ»ÑÑ Ð¾Ð±Ð»ÐµÐ³ÑÐµÐ½Ð¸Ñ Ð²Ð·Ð°Ð¸Ð¼Ð¾Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ñ ÑÐ¾ÑÑÑÐ´Ð½Ð¸ÐºÐ°Ð¼Ð¸ Ð¸ Ð°Ð´Ð¼Ð¸Ð½Ð¸ÑÑÑÐ°ÑÐ¸ÐµÐ¹. ÐÑÐ» Ð¿ÑÐ¾Ð²ÐµÐ´ÑÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ñ Ð°Ð½Ð°Ð»Ð¾Ð³Ð¾Ð², Ð² ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²Ð¸Ð¸ Ñ Ð¿Ð¾ÑÑÐ°Ð²Ð»ÐµÐ½Ð½ÑÐ¼Ð¸ Ð·Ð°Ð´Ð°ÑÐ°Ð¼Ð¸ ÑÐµÐ°Ð»Ð¸Ð·Ð¾Ð²Ð°Ð½ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½ÑÐ¹ Ð¿ÑÐ¾Ð´ÑÐºÑ â Ð¿ÑÐ¾ÑÐ¾ÑÐ¸Ð¿ Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ, Ð° ÑÐ°ÐºÐ¶Ðµ Ð½Ð°Ð¹Ð´ÐµÐ½Ñ Ð¿ÑÑÐ¸ ÐµÐ³Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ.
Mappa stellare di Gaia 2.0
Creators: Alberto Laratro
Publisher: name: Media Inaf
Year: 2018

Verrà resa pubblica il 25 aprile prossimo la seconda infornata di dati raccolti da Gaia, la missione spaziale dell’Esa che cerca di creare una mappa tridimensionale della nostra galassia, il più grande catalogo astrometrico mai prodotto
A topological Dirac insulator in a quantum spin Hall phase : Experimental observation of first strong topological insulator
Creators: name: Hsieh, D.
name: Qian, D.
name: Wray, L.
name: Xia, Y.
name: Hor, Y. S.
name: Cava, R. J.
name: Hasan, M. Z.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: When electrons are subject to a large external magnetic field, the conventional charge quantum Hall effect \cite{Klitzing,Tsui} dictates that an electronic excitation gap is generated in the sample bulk, but metallic conduction is permitted at the boundary. Recent theoretical models suggest that certain bulk insulators with large spin-orbit interactions may also naturally support conducting topological boundary states in the extreme quantum limit, which opens up the possibility for studying unusual quantum Hall-like phenomena in zero external magnetic field. Bulk Bi$_{1-x}$Sb$_x$ single crystals are expected to be prime candidates for one such unusual Hall phase of matter known as the topological insulator. The hallmark of a topological insulator is the existence of metallic surface states that are higher dimensional analogues of the edge states that characterize a spin Hall insulator. In addition to its interesting boundary states, the bulk of Bi$_{1-x}$Sb$_x$ is predicted to exhibit three-dimensional Dirac particles, another topic of heightened current interest. Here, using incident-photon-energy-modulated (IPEM-ARPES), we report the first direct observation of massive Dirac particles in the bulk of Bi$_{0.9}$Sb$_{0.1}$, locate the Kramers' points at the sample's boundary and provide a comprehensive mapping of the topological Dirac insulator's gapless surface modes. These findings taken together suggest that the observed surface state on the boundary of the bulk insulator is a realization of the much sought exotic "topological metal". They also suggest that this material has potential application in developing next-generation quantum computing devices.
description: 16 pages, 3 Figures. Submitted to NATURE on 25th November(2007)
Molecular origins of cancer specific alternative splicing events
Creators: name: Ilhan, Serife
Publisher: name: Hochschule für Life Sciences FHNW
Year: 2023
Subjects: subject: 500 - Naturwissenschaften und Mathematik

description: Die molekularen Mechanismen von Transkript-Switching-Events bleiben weitgehend unklar. Das Ziel dieser Arbeit war die molekularen Ursprünge von krebsspezifischen Alternative Splicing Events zu untersuchen. Dafür wurden mehrere Machine Learning Modelle implementiert. Es wurde ein Datenset erstellt, welche Daten über Methylierung, Mutationen, Gen Expression, Copy Number Alteration, Transkript Expression, Alter bei der Diagnose und das Geschlecht beinhalteten. Es wurde beobachtet, dass die Methylierung, Anzahl Spliceosome Mutationen und das Alter bei der Diagnose einen Zusammenhang mit der Zielvariable Transcript-Switching-Event aufweist. Auch wurde eine Korrelation zwischen den beiden Features Spliceosome Mutationen und das Alter bei der Diagnose beobachtet. Die Implementierten Modelle konnten eine Beziehung zeigen, jedoch sind weitere Forschungen nötig.
INTEGRATING LITERARY TEXTS TO ENHANCE VOCABULARY AND READING FLUENCY IN PHILOLOGY STUDENTS
Creators: name: Saidov, Ravshan
Publisher: name: Zenodo
Year: 2025

description: This article explores the integration of literary texts in philology education to enhance vocabulary acquisition and reading fluency. Literary texts serve as a rich linguistic resource, exposing students to diverse vocabulary and authentic language use. The study highlights approaches to using literature in the classroom, practical implementation strategies, and the benefits and challenges of this method. By fostering reading competence, literary texts prepare students for academic and professional success in the field of philology.
title: ÐÐ¾Ð»ÑÑÐµÐ½Ð¸Ðµ Ð¿Ð¾ÑÐ¸ÑÑÐ¾Ð³Ð¾ ÐºÑÐµÐ¼Ð½Ð¸Ñ, Ð»ÐµÐ³Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð½Ð°Ð½Ð¾ÑÐ°ÑÑÐ¸ÑÐ°Ð¼Ð¸ Ð·Ð¾Ð»Ð¾ÑÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð©ÐµÑÐ±Ð°ÐºÐ¾Ð²Ð°, Ð¢Ð°ÑÑÑÐ½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¿Ð¾ÑÐ¸ÑÑÑÐ¹ ÐºÑÐµÐ¼Ð½Ð¸Ð¹
Ð½Ð°Ð½Ð¾ÑÐ°ÑÑÐ¸ÑÑ Ð·Ð¾Ð»Ð¾ÑÐ°
ÑÐ»ÐµÐºÑÑÐ¾Ñ Ð¸Ð¼Ð¸ÑÐµÑÐºÐ¾Ðµ ÑÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ

description: ÐÐ¿Ð¸ÑÐ°Ð½Ñ ÑÐ¿Ð¾ÑÐ¾Ð±Ñ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾ÑÐ¸ÑÑÑÑ ÑÑÑÑÐºÑÑÑ Ð½Ð° Ð¿Ð¾Ð²ÐµÑÑÐ½Ð¾ÑÑÐ¸ ÐºÑÐµÐ¼Ð½Ð¸Ñ. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½ Ð¾Ð±Ð·Ð¾Ñ Ð¿ÑÐ±Ð»Ð¸ÐºÐ°ÑÐ¸Ð¹, Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð½ÑÑ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾ÑÐ¸ÑÑÐ¾Ð³Ð¾ ÐºÑÐµÐ¼Ð½Ð¸Ñ (ÐÐ) ÑÐ»ÐµÐºÑÑÐ¾ÑÐ¸Ð¼Ð¸ÑÐµÑÐºÐ¸Ð¼ Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼ Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÐµÐ³Ð¾ Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸ ÑÑÑÑÐºÑÑÑÐ½ÑÑ ÑÐ²Ð¾Ð¹ÑÑÐ². ÐÐ°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÑ ÑÑÐ¸Ñ ÑÐ²Ð¾Ð¹ÑÑÐ² Ð¾Ñ ÑÐµÐ¶Ð¸Ð¼Ð¾Ð² Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ ÐÐ Ð¸ Ð²Ð½ÐµÐ´ÑÐµÐ½Ð½ÑÑ Ð¼ÐµÑÐ°Ð»Ð»Ð¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð½Ð¾ÑÐ°ÑÑÐ¸Ñ. ÐÑÑÐ²Ð»ÐµÐ½Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ ÐÐ, Ð»ÐµÐ³Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð·Ð¾Ð»Ð¾ÑÑÐ¼Ð¸ Ð½Ð°Ð½Ð¾ÑÐ°ÑÑÐ¸ÑÐ°Ð¼Ð¸.
title: ÐÐ°ÑÐ¶Ð¸Ð½Ð°Ð»Ð¸ÑÑÑÐºÐ°Ñ ÑÐµÐ²Ð¾Ð»ÑÑÐ¸Ñ Ð¸ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð½ÐµÐ¾ÐºÐ»Ð°ÑÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÐµÐ¾ÑÐ¸Ð¸
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð¿Ð¾ ÐºÑÑÑÑ "ÐÑÑÐ¾ÑÐ¸Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐµÐ½Ð¸Ð¹" Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÐµÐ¹
titleType: Subtitle
Creators: name: ÐÐµÐ¼Ð¸Ð´Ð¾Ð²Ð°, ÐÐ°ÑÐ¸Ð½Ð°
Publisher: name: Ð¡ÐÐ±Ð¢Ð­Ð
Year: 2006
Subjects: Ð¼Ð°ÑÐ¶Ð¸Ð½Ð°Ð»Ð¸Ð·Ð¼
ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ°Ñ ÑÐµÐ¾ÑÐ¸Ñ
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: ÐÐ¾ÑÐ¾Ð±Ð¸Ðµ ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÐµÑ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð¼Ñ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð¼Ñ ÑÑÐ°Ð½Ð´Ð°ÑÑÑ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ñ "ÐÑÑÐ¾ÑÐ¸Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐµÐ½Ð¸Ð¹" Ð¸ ÑÐ¾Ð´ÐµÑÐ¶Ð¸Ñ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´Ð²ÑÑ ÑÑÐ°Ð¿Ð¾Ð² Ð¼Ð°ÑÐ¶Ð¸Ð½Ð°Ð»Ð¸ÑÑÑÐºÐ¾Ð¹ ÑÐµÐ²Ð¾Ð»ÑÑÐ¸Ð¸ Ð¸ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ ÐºÐ¾Ð½ÑÐµÐ¿ÑÐ¸Ð¹ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð¸ÑÐµÐ»ÐµÐ¹ Ð¼Ð°ÑÐ¶Ð¸Ð½Ð°Ð»Ð¸Ð·Ð¼Ð°. ÐÐ¾ÑÐ¾Ð±Ð¸Ðµ Ð¼Ð¾Ð¶ÐµÑ Ð±ÑÑÑ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð¾Ð²Ð°Ð½Ð¾ ÑÑÑÐ´ÐµÐ½ÑÐ°Ð¼, Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ð¼ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ñ "ÐÑÑÐ¾ÑÐ¸Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐµÐ½Ð¸Ð¹", Ð° ÑÐ°ÐºÐ¶Ðµ Ð²ÑÐµÐ¼, Ð¸Ð½ÑÐµÑÐµÑÑÑÑÐ¸Ð¼ÑÑ Ð¸ÑÑÐ¾ÑÐ¸ÐµÐ¹ Ð¼Ð¸ÑÐ¾Ð²Ð¾Ð¹ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð¼ÑÑÐ»Ð¸.
Giant magnetoresistance in semiconductor / granular film heterostructures with cobalt nanoparticles
Creators: name: Lutsev, L. V.
name: Stognij, A. I.
name: Novitskii, N. N.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We have studied the electron transport in SiO${}_2$(Co)/GaAs and SiO${}_2$(Co)/Si heterostructures, where the SiO${}_2$(Co) structure is the granular SiO${}_2$ film with Co nanoparticles. In SiO${}_2$(Co)/GaAs heterostructures giant magnetoresistance effect is observed. The effect has positive values, is expressed, when electrons are injected from the granular film into the GaAs semiconductor, and has the temperature-peak type character. The temperature location of the effect depends on the Co concentration and can be shifted by the applied electrical field. For the SiO${}_2$(Co)/GaAs heterostructure with 71 at.% Co the magnetoresistance reaches 1000 ($10^5$ %) at room temperature. On the contrary, for SiO${}_2$(Co)/Si heterostructures magnetoresistance values are very small (4%) and for SiO${}_2$(Co) films the magnetoresistance has an opposite value. High values of the magnetoresistance effect in SiO${}_2$(Co)/GaAs heterostructures have been explained by magnetic-field-controlled process of impact ionization in the vicinity of the spin-dependent potential barrier formed in the semiconductor near the interface. Kinetic energy of electrons, which pass through the barrier and trigger the avalanche process, is reduced by the applied magnetic field. This electron energy suppression postpones the onset of the impact ionization to higher electric fields and results in the giant magnetoresistance. The spin-dependent potential barrier is due to the exchange interaction between electrons in the accumulation electron layer in the semiconductor and $d$-electrons of Co.
description: 25 pages, 16 figures
title: Ð¡Ð¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¼ÐµÑ Ð°Ð½Ð¸Ð·Ð¼Ð¾Ð² ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÐºÐ¾ÑÐ¿Ð¾ÑÐ°ÑÐ¸Ð²Ð½ÑÐ¼Ð¸ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½ÑÐ¼Ð¸ ÑÐ¸ÑÐ¼Ð°Ð¼Ð¸
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: Ð¡Ð¾ÐºÐ¾Ð»Ð¸ÑÑÐ½, ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
name: ÐÐ²Ð°Ð½Ð¾Ð², ÐÐ°ÐºÑÐ¸Ð¼
name: Ð¡Ð¾ÐºÐ¾Ð»Ð¸ÑÑÐ½Ð°, ÐÐ°ÑÐ°Ð»ÑÑ
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2015
Subjects: ÐºÐ¾ÑÐ¿Ð¾ÑÐ°ÑÐ¸Ð²Ð½Ð¾Ðµ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ
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description: Ð ÑÑÐµÐ±Ð½Ð¾Ð¼ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð²Ð°Ð¶Ð½ÐµÐ¹ÑÐ¸Ðµ Ð·Ð°Ð´Ð°ÑÐ¸ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ, ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÐºÐ¾ÑÐ¿Ð¾ÑÐ°ÑÐ¸Ð²Ð½ÑÑ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½ÑÑ ÑÐ¸ÑÐ¼. ÐÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð¾ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ ÑÐµÑÑÑÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾ÑÐ¿Ð¾ÑÐ°ÑÐ¸Ð²Ð½ÑÑ ÑÐ¸ÑÐ¼. ÐÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ¾-Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ ÑÐ¾Ð³Ð»Ð°ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¸Ð½ÑÐµÑÐµÑÐ¾Ð² Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð³Ð¾ÑÐ¸Ð·Ð¾Ð½ÑÐ°Ð»ÑÐ½Ð¾-Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ, Ð´Ð¸Ð²ÐµÑÑÐ¸ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð¸ Ð²ÐµÑÑÐ¸ÐºÐ°Ð»ÑÐ½Ð¾-Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ ÐºÐ¾ÑÐ¿Ð¾ÑÐ°ÑÐ¸Ð²Ð½ÑÑ ÑÐ¸ÑÐ¼. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¾ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÑÑÐ°ÑÐµÐ³Ð¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ð¹ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÐºÐ¾ÑÐ¿Ð¾ÑÐ°ÑÐ¸Ð²Ð½ÑÑ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½ÑÑ ÑÐ¸ÑÐ¼ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ½Ð¾Ð³Ð¾ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð°. ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ°ÑÑÐ½Ð¾Ð³Ð¾ Ð¿Ð°ÑÑÐ½ÐµÑÑÑÐ²Ð°. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¾ ÑÐ¾Ð³Ð»Ð°ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¸Ð½ÑÐµÑÐµÑÐ¾Ð² Ð¿ÑÐ±Ð»Ð¸ÑÐ½Ð¾Ð³Ð¾ Ð¸ ÑÐ°ÑÑÐ½ÑÑ Ð¿Ð°ÑÑÐ½ÐµÑÐ¾Ð² - ÐºÐ¾ÑÐ¿Ð¾ÑÐ°ÑÐ¸Ð²Ð½ÑÑ ÑÐ¸ÑÐ¼ - ÐºÐ°Ðº Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½Ñ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÐÐ§Ð. ÐÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð°ÑÐ¿Ð¸ÑÐ°Ð½ÑÐ¾Ð², Ð¿ÑÐµÐ¿Ð¾Ð´Ð°Ð²Ð°ÑÐµÐ»ÐµÐ¹ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÐµÐ¹ Ð²ÑÐ·Ð¾Ð², ÑÑÐºÐ¾Ð²Ð¾Ð´ÑÑÐ¸Ñ ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ¾Ð² Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¹, ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ¾Ð² Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¸ Ð¼ÑÐ½Ð¸ÑÐ¸Ð¿Ð°Ð»ÑÐ½ÑÑ Ð¾ÑÐ³Ð°Ð½Ð¾Ð² Ð²Ð»Ð°ÑÑÐ¸, ÑÐ¸ÑÐ¾ÐºÐ¾Ð³Ð¾ ÐºÑÑÐ³Ð° ÑÐ¸ÑÐ°ÑÐµÐ»ÐµÐ¹, Ð¸Ð½ÑÐµÑÐµÑÑÑÑÐ¸ÑÑÑ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ð°Ð¼Ð¸ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½ÑÑ ÑÐ¸ÑÐ¼.
Cheops il misura-pianeti va a Madrid
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2018

Superati con successo tutti i collaudi, il telescopio spaziale Cheops dell’Esa per la caratterizzazione dei pianeti extrasolari è ora pronto alla fase di integrazione. Nel 2019 il lancio dalla Guiana francese. Ne parliamo con due scienziati della missione, Isabella Pagano dell’Inaf di Catania e Roberto Ragazzoni dell’Inaf di Padova
Exploration of structural alerts and fingerprints for novel anticancer therapeutics: a robust classification-QSAR dependent structural analysis of drug-like MMP-9 inhibitors
Creators: name: Banerjee, S.
name: Baidya, S.K.
name: Ghosh, B.
name: Jha, T.
name: Adhikari, N.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Among various matrix metalloproteinases (MMPs), overexpression of MMP9 has been established as a key player in a variety of cancers. Therefore, MMP9 has emerged as a promising biomolecule that may be targeted to design potent inhibitors as novel anticancer therapeutics. In this study, a large database containing 1,123 drug-like MMP-9 inhibitors was considered for robust classification-dependent fragment-based QSAR study through SARpy, Bayesian classification, and recursive partitioning analyses and were validated by both internal and external validation techniques. In a nutshell, all these classification-dependent techniques revealed some common structural alerts and sub-structural fingerprints responsible for modulating MMP-9 inhibition. These observations are in agreement with the interactions obtained from the ligand-bound co-crystal structures of MMP-9 justifying the robustness of the current study. Finally, based on these crucial structural fragments, some new lead compounds were designed and further validated by the binding mode of interaction analysis. Therefore, these findings may be beneficial in designing novel and potential MMP-9 inhibitors in the future as a weapon to combat several cancers.
Da Napoli a Marte, un ticket per MicroMed
Creators: Marco Galliani
Publisher: name: Media Inaf
Year: 2018

La Regione Campania ha deliberato il sostegno economico allo strumento tutto made in Italy che studierà le tempeste di polvere sul pianeta Rosso durante la missione Exomars 2020. Media Inaf ha intervistato Francesca Esposito dell'Inaf di Napoli, responsabile scientifica di MicroMed
Contrordine, la materia oscura non interagisce
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2018

Nuove osservazioni condotte con Alma mostrano che l’ipotesi di una materia oscura in grado d’interagire con forze diverse da quella di gravità, avanzata nel 2015 analizzando i dati raccolti con il telescopio spaziale Hubble, non può essere confermata
Development of binary classification models for grouping hydroxylated polychlorinated biphenyls into active and inactive thyroid hormone receptor agonists
Creators: name: Akinola, L.K.
name: Uzairu, A.
name: Shallangwa, G.A.
name: Abechi, S.E.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified

description: Some adverse effects of hydroxylated polychlorinated biphenyls (OH-PCBs) in humans are presumed to be initiated via thyroid hormone receptor (TR) binding. Due to the trial-and-error approach adopted for OH-PCB selection in previous studies, experiments designed to test the TR binding hypothesis mostly utilized inactive OH-PCBs, leading to considerable waste of time, effort and other material resources. In this paper, linear discriminant analysis (LDA) and binary logistic regression (LR) were used to develop classification models to group OH-PCBs into active and inactive TR agonists using radial distribution function (RDF) descriptors as predictor variables. The classifications made by both LDA and LR models on the training set compounds resulted in an accuracy of 84.3%, sensitivity of 72.2% and specificity of 90.9%. The areas under the ROC curves, constructed with the training set data, were found to be 0.872 and 0.880 for LDA and LR models, respectively. External validation of the models revealed that 76.5% of the test set compounds were correctly classified by both LDA and LR models. These findings suggest that the two models reported in this paper are good and reliable for classifying OH-PCB congeners into active and inactive TR agonists.
Nel cerchio di luce, una stella morta
Creators: Redazione Eso
Publisher: name: Media Inaf
Year: 2018

Lo strumento Muse dell’Eso, al Vlt, ha potuto stabilire dove si nasconde questo oggetto elusivo, mentre le osservazioni preesistenti di Chandra ne hanno confermato l'identità di stella di neutroni isolata: la prima per la quale abbiamo conferma che si trovi al di fuori della Via Lattea
Un centesimo di pixel: l’acrobazia di Hubble
Creators: Alberto Laratro
Publisher: name: Media Inaf
Year: 2018

Calcolata la distanza di un antico ammasso globulare nella nostra galassia grazie a un modo nuovo di applicare un metodo risalente all’antica Grecia. Risultato: Ngc 6397 si trova a 7800 anni luce da noi, con un margine d’errore di appena il tre per cento
The radii of M-dwarfs in the young open cluster NGC 2516
Creators: name: Jackson, R. J.
name: Jeffries, R. D.
name: Maxted, P. F. L.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Using a novel technique, which combines previously determined rotation periods with new spectroscopic determinations of projected rotation velocity, we have determined radii for fast rotating, low-mass (0.2-0.7 Msun) M-dwarfs in the young, solar-metallicity open cluster, NGC 2516. The mean radii are larger than model predictions at a given absolute I or K magnitude and also larger than the measured radii of magnetically inactive M-dwarfs; the difference increases from a few per cent, to 50 per cent for the lowest luminosity stars in our sample. We show that a simple two-temperature starspot model is broadly capable of explaining these observations, but requires spot coverage fractions of about 50 per cent in rapidly rotating M-dwarfs.
description: Accepted for MNRAS letters (5 pages)
Parker, in missione là dove il Sole brucia
Creators: Antonio Mancino
Publisher: name: Media Inaf
Year: 2018

Si chiama Parker Solar Probe e si spingerà vicino alla nostra stella più di quanto qualunque altra sonda abbia fatto mai: ad appena 6.2 milioni di km dalla fotosfera. Abbiamo intervistato uno dei responsabili scientifici della missione, l’italiano Marco Velli, scienziato della Nasa
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÑÐ°Ð½Ð´Ð°ÑÑÐ° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ "ÐÐ±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ðµ ÐºÐ°ÑÐµÑÑÐ²Ð° Ð¼Ð¾Ð½ÑÐ°Ð¶Ð½ÑÑ Ð¸ Ð¿ÑÑÐºÐ¾Ð½Ð°Ð»Ð°Ð´Ð¾ÑÐ½ÑÑ ÑÐ°Ð±Ð¾Ñ ÑÐ¸ÑÑÐµÐ¼ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸"
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐ¾ÑÐ¾Ð·, Ð®Ð»Ð¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÐÐ¾Ð¶Ð°ÑÐ½Ð¾Ðµ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ
Ð¼Ð¾Ð½ÑÐ°Ð¶Ð½ÑÐµ ÑÐ°Ð±Ð¾ÑÑ
Ð¿ÑÑÐºÐ¾Ð½Ð°Ð»Ð°Ð´Ð¾ÑÐ½ÑÐµ ÑÐ°Ð±Ð¾ÑÑ
ÑÑÐ°Ð½Ð´Ð°ÑÑ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸
ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸

description: ÐÐ°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¹ Ð¸ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð»ÑÐ³ÑÑ Ð² Ð¾ÑÐ½Ð¾Ð²Ñ ÑÑÐ°Ð½Ð´Ð°ÑÑÐ° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¿Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ ÐºÐ°ÑÐµÑÑÐ²Ð° Ð¼Ð¾Ð½ÑÐ°Ð¶Ð½ÑÑ Ð¸ Ð¿ÑÑÐºÐ¾Ð½Ð°Ð»Ð°Ð´Ð¾ÑÐ½ÑÑ ÑÐ°Ð±Ð¾Ñ ÑÐ¸ÑÑÐµÐ¼ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸. ÐÑÐ½Ð¾Ð²Ð¾Ð¹ Ð´Ð»Ñ ÑÐ°Ð±Ð¾ÑÑ Ð¿Ð¾ÑÐ»ÑÐ¶Ð¸Ð»Ð¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð½Ð°ÑÑÐ½ÑÑ Ð´Ð¾ÑÑÐ¸Ð¶ÐµÐ½Ð¸Ð¹ Ð¸ Ð½Ð¾ÑÐ¼Ð°ÑÐ¸Ð²Ð½Ð¾-ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ°Ñ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ñ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ ÐºÐ°ÑÐµÑÑÐ²Ð°.
Diecimila buchi neri al centro della Via Lattea
Creators: Alberto Laratro
Publisher: name: Media Inaf
Year: 2018

Al centro della Via Lattea è presente un buco nero supermassiccio, Sgr A*. Un nuovo studio pubblicato su Nature conferma l'ipotesi secondo cui sarebbe circondato da parecchie migliaia di buchi neri minori
Adaptation of TURN protocol to SIP protocol
Creators: name: Guezouri, Mustapha
name: Blaha, Ahmed
name: Keche, Mokhtar
Publisher: name: arXiv
Year: 2010
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Today, SIP is a protocol par Excellence in the field of communication over Internet. But, the fact that it belongs to the application layer constitutes a weakness vis-a-vis the NAT traversal. This weakness is due to the way in which the server replies to the requests of clients on the one hand. On the other, it is caused by the dynamic allocation of UDP ports for emission and reception of packets RTP/RTCP. The TURN Protocol may face this weakness. However, its use requires a certain number of exchanges between the clients and a TURN server before establishing the multimedia sessions and this increase the latent time. In this article, we propose to adapt TURN protocol for applications based on SIP protocol such as telephony over Internet, conference video, etc. This adaptation optimises the establishment of multimedia sessions by integrating a manager of TCP connections and multimedia flow controller into SIP Proxy server.
description: International Journal of Computer Science Issues, IJCSI, Vol. 7, Issue 1, No. 2, January 2010, http://ijcsi.org/articles/Adaptation-of-TURN-protocol-to-SIP-protocol.php
Synthesis, antiproliferative and 4D-QSAR studies of thiadiazole derivatives bearing acrylamide moiety as EGFR inhibitors
Creators: name: Cai, B.Y.
name: Zhao, T.S.
name: Qin, D.G.
name: Tu, G.G.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: As a target for clinical anti-cancer treatment, epidermal growth factor receptor (EGFR) exhibits its over-expression on various tumour cells and is associated with the development of a variety of human cancers. Herein, we described the synthesis, antiproliferative activity assay and 4D-QSAR studies of thiadiazole derivatives bearing acrylamide moiety as EGFR inhibitors. Compared with Gefitinib, some of the target compounds have excellent antiproliferative activities against EGFR-expressed A431 cell line. The robust and reliable 4D-QSAR was constructed using comparative distribution detection algorithm, ordered predictors selection and genetic algorithm method, and the following acceptable statistics are shown: r2 = 0.82, Q2LOO = 0.67, Q2LMO = 0.61, r2Pred = 0.78.