cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Factorial analyses of treatment effects under independent right-censoring
Creators: name: Dobler, Dennis
name: Pauly, Markus
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Factorial designs
subject: Kaplan-Meier estimator
subject: quadratic forms
subject: wild bootstrap
subject: MULTIPLE COMPARISON PROCEDURES
subject: RANK-BASED PROCEDURES
subject: NONPARAMETRIC METHODS
subject: TESTS
subject: DESIGNS
subject: DDC 500 / Natural sciences & mathematics
subject: DDC 610 / Medicine & health
subject: Factorial experiment designs
subject: Nonparametric statistics
subject: Forms, Quadratic
subject: Multiple comparisons (Statistics)
subject: Survival
subject: Examinations
subject: Bootstrap (Computer program)
subject: Therapy
subject: Aspirin
subject: Trials
subject: Faktorielle Versuchsplanung
subject: Kaplan-Meier-Schätzung
subject: Nichtparametrische Statistik
subject: Quadratische Form
subject: Überleben
subject: Bootstrap-Statistik
subject: Therapie
subject: Prozess

description: This paper introduces new effect parameters for factorial survival designs with possibly right-censored time-to-event data. In the special case of a two-sample design, it coincides with the concordance or Wilcoxon parameter in survival analysis. More generally, the new parameters describe treatment or interaction effects and we develop estimates and tests to infer their presence. We rigorously study their asymptotic properties and additionally suggest wild bootstrapping for a consistent and distribution-free application of the inference procedures. The small sample performance is discussed based on simulation results. The practical usefulness of the developed methodology is exemplified on a data example about patients with colon cancer by conducting one- and two-factorial analyses.
P4BID: Information Flow Control in P4
Creators: name: Grewal, Karuna
name: D'Antoni, Loris
name: Hsu, Justin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Programming Languages (cs.PL)
subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Modern programmable network switches can implement custom applications using efficient packet processing hardware, and the programming language P4 provides high-level constructs to program such switches. The increase in speed and programmability has inspired research in dataplane programming, where many complex functionalities, e.g., key-value stores and load balancers, can be implemented entirely in network switches. However, dataplane programs may suffer from novel security errors that are not traditionally found in network switches. To address this issue, we present a new information-flow control type system for P4. We formalize our type system in a recently-proposed core version of P4, and we prove a soundness theorem: well-typed programs satisfy non-interference. We also implement our type system in a tool, P4bid, which extends the type checker in the p4c compiler, the reference compiler for the latest version of P4. We present several case studies showing that natural security, integrity, and isolation properties in networks can be captured by non-interference, and our type system can detect violations of these properties while certifying correct programs.
title: Культурные ценности как предмет хищения
title: Учебное пособие
titleType: Subtitle
Creators: name: Герасимова Е.В.
Publisher: name: Вузовское образование
Year: 2018

description: Пособие посвящено исследованию признаков предмета преступления, предусмотренного ст. 164 УК РФ. В пособие на основе анализа уголовного законодательства, постановлений Пленума ВС РФ, а также сложившейся судебной практики и доктринальной литературы по вопросам особенностей ответственности за хищение чужого имущества, рассматриваются основные признаки предмета хищения. Автор представленного пособия обобщил ряд проблем, возникающих не только в ходе толкования, но и в процессе правоприменения ст. 164 УК РФ. В юридической литературе неоднократно отмечались различные неточности законодательного построения диспозиции ст. 164 УК РФ. Предназначено студентам, изучающим курс «Уголовное право РФ. Особенная часть», аспирантам, преподавателям юридических вузов, а также самому широкому кругу читателей, интересующихся вопросами уголовно-правовой проблематики.
description: The manual is devoted to the study of the characteristics of a crime under article 164 of the criminal code. In the manual is based on the analysis of criminal law decisions of the Plenum of the RF armed forces, as well as current judicial practice and doctrinal literature on the characteristics of liability for misappropriation, discusses the main features of the subject of theft. The author presents the benefits have summarized a number of problems arising not only in the interpretation but also in the enforcement process article 164 of the criminal code. In the legal literature it was repeatedly noted various inaccuracies of the legislative construction of the provisions of article 164 of the criminal code. Designed for the students studying the course "Criminal law of the Russian Federation. Special part", graduate students, law professors, and a wide range of readers interested in the issues of criminal-legal issues.
sj-docx-2-dmj-10.1177_1089313X231177174 – Supplemental material for Comparison of Impact Accelerations During Performance of Common Ballet Maneuvers: A Pilot Study
Creators: name: Fallon, Caitlin
name: Yang, Paj
name: Lown, Misty
name: Reilly, Michelle
name: Bednarz, Nicole
name: Gamoke, Kyle
name: Morgan, Alexander
name: Almonroeder, Thomas Gus
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, sj-docx-2-dmj-10.1177_1089313X231177174 for Comparison of Impact Accelerations During Performance of Common Ballet Maneuvers: A Pilot Study by Caitlin Fallon, Paj Yang, Misty Lown, Michelle Reilly, Nicole Bednarz, Kyle Gamoke, Alexander Morgan and Thomas Gus Almonroeder in Journal of Dance Medicine & Science
title: Обстоятельства, исключающие преступность деяния: необходимая оборона, причинение вреда при задержании лица, совершившего преступление, крайняя необходимость
title: Учебно-практическое пособие
titleType: Subtitle
Creators: name: Герасимова Е.В.
Publisher: name: Вузовское образование
Year: 2018

description: Настоящее учебно-практическое пособие посвящено исследованию особенностей отдельных видов обстоятельств, исключающих преступность деяния. В пособии на основе анализа уголовного законодательства, постановлений Пленума Верховного Суда РФ, а также сложившейся судебной практики и доктринальной литературы рассматриваются условия правомерности необходимой обороны, причинения вреда при задержании лица, совершившего преступление, и крайней необходимости. В работе исследуются понятие «эксцесс обороны» и его признаки, рассматриваются критерии установления превышения мер, необходимых для задержания лица, совершившего преступление, а также превышения пределов крайней необходимости. Адресуется студентам, изучающим курс «Уголовное право РФ. Общая часть», аспирантам, преподавателям юридических вузов, а также самому широкому кругу читателей, интересующихся вопросами уголовно-правовой проблематики.
description: The present textbook is devoted to the study of the peculiarities of individual kinds of the circumstances excluding criminality of act. In the manual on the basis of analysis of the criminal law, resolutions of the Plenum of the Supreme Court and the current judicial practice and doctrinal literature deals with the conditions of lawfulness of necessary defense, infliction of harm at detention of the person committed a crime and extreme necessity. This paper investigates the concept of "excess of defense" and of his signs are considered criteria of exceeding measures necessary for detention of person who committed the crime, as well as exceeding the limits of extreme necessity. Addressed to students of the course "Criminal law of the Russian Federation. General part", graduate students, law professors, and a wide range of readers interested in the issues of criminal-legal issues.
Additional file 1 of The first two whole mitochondrial genomes for the genus Dactylis species: assembly and comparative genomics analysis
Creators: name: Feng, Guangyan
name: Jiao, Yongjuan
name: Ma, Huizhen
name: Bian, Haoyang
name: Nie, Gang
name: Huang, Linkai
name: Xie, Zheni
name: Ran, Qifan
name: Fan, Wenwen
name: He, Wei
name: Zhang, Xinquan
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Additional file 1: Fig. S1. The information of sequencing data. a and b, The raw data of the third-generation sequencing read length distribution of Dactylis aschersoniana and Dactylis glomerata, respectively; c and d, The A/T/G/C content distribution statistics of Dactylis glomerata and Dactylis aschersoniana, respectively. Fig. S2. Base error rate and quality distribution. a and b, The error rate distribution of Dactylis aschersoniana and Dactylis glomerata, respectively; c and d are quality distribution of Dactylis aschersoniana and Dactylis glomerata, respectively. Fig. S3. Sequencing depth and coverage map of chloroplast and mitochondrial genomes. a and b represent the sequencing depth of coverage map from the chloroplast genomes of Dactylis aschersoniana and Dactylis glomerata. c and d represent the sequencing depth of coverage map from the mitochondrial genomes of Dactylis aschersoniana and Dactylis glomerata. Fig. S4. The sequence identity maps of two Dactylis mitochondrial genomes. The gray arrow above the alignment indicates the direction of the gene. Blue stripes represent exons, and pink stripes represent non-coding sequences (CNSs). The graph uses a critical value of 50 % identity. The Y axis represents the identity percentage in the range of 50-100 %. Fig. S5. Codon distribution map in the Dactylis mt genome. Red indicates a high relative synonymous codon usage (RSCU) value and green indicates a low RSCU value. Hierarchical clustering (average linkage method) was performed for the codon patterns (x-axis). Fig. S6. The base sequence dot-plot diagram of Dactylis aschersoniana, Dactylis glomerata and other two species.
Proposal to repeat the Abraham force experiment using giant permittivity materials
Creators: name: Brevik, Iver
Publisher: name: arXiv
Year: 2022
Subjects: subject: Classical Physics (physics.class-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: In the more than 100 years-old Abraham-Minkowski problem in macroscopic electrodynamics, the issue of how to observe the so-called Abraham term ${\bf f}^{\rm Aterm} = [(\varepsilonμ-1)/c^2] \partial/\partial t ({\bf E}\times {\bf H})$ has been a main point. Recent years have seen a number of beautiful experiments in radiation optics, but these experiments usually give no information about the Abraham term as this term simply fluctuates out. So one is left with somewhat indirect verifications of this force, as in the radiation pressure of Jones {et al.} in the 1950's, testing the radiation pressure on a mirror immersed in a dielectric liquid. Now, there is a different way to test the existence of ${\bf f}^{ \rm Aterm}$, namely to work with low (quasi-stationary) frequencies enabling one to observe the sinusoidal variation of the force directly. These kind of experiments were actually done by Walker {\it et al.} in 1he 1970's, using BaTiO$_3$ as a high-frequency dielectric (permittivity $\varepsilon \sim 3600$). Now, in recent years there have appeared dielectric materials with giant permittivities, of order $10^5$ or even higher. It is therefore natural to consider the idea of Walker {\it et al.} anew, in order to test if this demanding experiment can be facilitated and give better accuracy. That is the main topic of the present paper. The positive outcome of these kinds of experiments clearly supports the Abraham energy-momentum tensor at low frequencies. The Minkowski tensor is unable to predict a torque at all. The low-frequency and the high-frequency regimes are in this way highly contrasted, as it is obvious that in optical experiments the Minkowski tensor is by far the simplest and most convenient one to use. We end this note by commenting upon the use of the Einstein-Laub tensor (1908) in explaining this experiment, and discuss also the influence from air friction.
description: 7 pages, latex, to appear in Int. J. Mod. Phys. A
Supplemental Material - Granular cell tumor of the lung and tracheobronchial tree: two case-presentation with a review of the literature
Creators: name: Houcine, Yoldez
name: Mlika, Mouna
name: Moussa, Chirine
name: Rouis, Houda
name: Brahem, Emna
name: Ismail, Olfa
name: Maȃlej, Sonia
name: El Mezni, Faouzi
Publisher: name: SAGE Journals
Year: 2023
Subjects: Oncology and Carcinogenesis not elsewhere classified

description: Granular cell tumor of the lung and tracheobronchial tree: two case-presentation with a review of the literature by Yoldez Houcine, Mouna Mlika, Chirine Moussa, Houda Rouis, Emna Brahem, Olfa Ismail, Sonia Maȃlej and Faouzi El Mezni in Rare Tumors
Unveiling the Patterns of Reticulated Evolutionary Processes with Phylogenomics: Hybridization and Polyploidy in the genus Rosa
Creators: name: Foucher, Fabrice
name: Kevin, Debray
name: Lepaslier, Marie-Christine
name: Bérard, Aurélie
name: Thouroude, Tatiana
name: Michel, Gilles
name: Marie-Magdeleine, Jordan
name: Bruneau, Anne
name: Malécot, Valéry
Publisher: name: Zenodo
Year: 2021
Subjects: polyploid detection
Interspecific hybridization

description: Reticulation, caused by hybridization and allopolyploidization, is considered an important and frequent phenomenon in the evolution of numerous plant lineages. Although both processes represent important driving forces of evolution, they are mostly ignored in phylogenetic studies involving a large number of species. Indeed only a scattering of methods exists to recover a comprehensive reticulated evolutionary history for a broad taxon sampling. Plastid markers, sometimes combined with a few nuclear sequences, are therefore favored, even though they restrict in-depth studies of hybridization and polyploidization. The genus Rosa encompasses c. 150 species widely distributed throughout the northern hemisphere and represents a challenging taxonomic group in which hybridization and polyploidization are prominent. Our main objective was to develop a general framework that would take patterns of reticulation into account in the study of the phylogenetic relationships among Rosa species. Using amplicon sequencing we targeted allele variation in the nuclear genome as well as haploid sequences in the chloroplast genome. A stepwise diploids-first approach was developed to reconstruct the reticulate evolutionary history of the genus Rosa. We successfully recovered robust plastid and nuclear phylogenies and performed in-depth tests for several scenarios of hybridization. Using this strategy, we were able to resolve most of the evolutionary relationships among Rosa subgenera, sections, and selected species, and we provide new directions for a future revision of the infrageneric classification in Rosa. The stepwise strategy proposed here can be used to reconstruct the phylogenetic relationships of other challenging taxonomic groups with large numbers of hybrid and polyploid taxa.
description: Funding provided by: Conseil Régional des Pays de la Loire
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100013414
Award Number: RFI Objectif VégétalFunding provided by: Ministère de l'Enseignement Supérieur et de la Recherche Scientifique
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100012964
Award Number: Funding provided by: European Regional Development Fund
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100008530
Award Number: Funding provided by: Angers Loire Métropole
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100007745
Award Number:
description: The methods are described in the manuscript associated with the data.
Bad metal and negative compressibility transitions in a two-band Hubbard model
Creators: name: Fresard, Raymond
name: Steffen, Kevin
name: Kopp, Thilo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We analyze the paramagnetic state of a two-band Hubbard model with finite Hund's coupling close to integer filling at $n=2$ in two spacial dimensions. Previously, a Mott metal-insulator transition was established at $n=2$ with a coexistence region of a metallic and a bad metal state in the vicinity of that integer filling. The coexistence region ends at a critical point beyond which a charge instability persists. Here we investigate the transition into negative electronic compressibility states for an extended filling range close to $n=2$ within a slave boson setup. We analyze the separate contributions from the (fermionic) quasiparticles and the (bosonic) multiparticle incoherent background and find that the total compressibility depends on a subtle interplay between the quasiparticle excitations and collective fields. Implementing a Blume-Emery-Griffiths model approach for the slave bosons, which mimics the bosonic fields by Ising-like pseudospins, we suggest a feedback mechanism between these fields and the fermionic degrees of freedom. We argue that the negative compressibility can be sustained for heterostructures of such strongly correlated planes and results in a large capacitance of these structures. The strong density dependence of these capacitances allows to tune them through small electronic density variations. Moreover, by resistive switching from a Mott insulating state to a metallic state through short electric pulses, transitions between fairly different capacitances are within reach.
description: 23 pages, 18 figures
Supplementary Figure 3:
Creators: name: Piyarungsri, Kakanang
name: Chuammitri, Phongsakorn
name: Pringproa, Kidsadagon
name: Pila, Pattiya
name: Srivorakul, Saralee
name: Sornpet, Benjaporn
name: Pusoonthornthum, Rosama
Publisher: name: SAGE Journals
Year: 2023
Subjects: Veterinary Medicine

description: In periodic acid–Schiff-stained sections, interstitial fibrosis scoring included grades 0–4.
Uniparental disomy in somatic mosaicism 45,X/46,XY/46,XX associated with ambiguous genitalia
Creators: name: Serra, Alexandre
name: Denzer, Friederike
name: Hiort, Olaf
name: Barth, Thomas F. E.
name: Henne-Bruns, Doris
name: Barbi, Gotthold
name: Rettenberger, Günther
name: Wabitsch, Martin
name: Just, Walter
name: Leriche, Clothilde
Publisher: name: Universität Ulm
Year: 2015
Subjects: subject: Ambiguous genitalia
subject: Somatic mosaicism 45,X/46,XY/46,XX
subject: true hermaphroditism
subject: 46,xx/46,xy hermaphrodite
subject: prenatal-diagnosis
subject: human chimera
subject: mechanism
subject: DDC 610 / Medicine & health
subject: Disorders of sex development
subject: Uniparental disomy
subject: Ovotesticular disorders of sex development
subject: Fertilization
subject: Karyotype
subject: Intersexualität

description: Disorders of sex development (DSD) affect the development of chromosomal, gonadal and/or anatomical sex. We analyzed a patient with ambiguous genitalia aiming to correlate the genetic findings with the phenotype. Blood and tissue samples from a male patient with penoscrotal hypospadias were analyzed by immunohistochemistry, karyotyping and FISH. DNA was sequenced for the AR, SRY and DHH genes, and further 26 loci in different sex chromosomes were analyzed by MLPA. The gonosomal origin was evaluated by simple tandem repeat (STR) analysis and SNP array. Histopathology revealed a streak gonad, a fallopian tube and a rudimentary uterus, positive for placental alkaline phosphatase, cytokeratin-7 and c-kit, and negative for estrogen, androgen and progesterone receptors, alpha-inhibin, alpha-1-fetoprotein, β-hCG, and oct-4. Karyotyping showed a 45,X/46,XY mosaicism, yet FISH showed both 46,XX/46,XY mosaicism (gonad and urethral plate), 46,XX (uterus and tube) and 46,XY karyotypes (rudimentary testicular tissue). DNA sequencing revealed intact sequences in SOX9, WNT4, NR0B1, NR5A1, CYP21A2, SRY, AR, and DHH. STR analysis showed only one maternal allele for all X chromosome markers (uniparental isodisomy, UPD), with a weaker SRY signal and a 4:1 ratio in the X:Y signal. Our findings suggest that the observed complex DSD phenotype is the result of somatic gonosomal mosaicism and UPD despite a normal blood karyotype. The presence of UPD warrants adequate genetic counseling for the family and frequent, lifelong, preventive follow-up controls in the patient. © In Copyright http://rightsstatements.org/vocab/InC/1.0/
Additional file 2 of Adhesion of Candida Albicans to digital versus conventional acrylic resins: a systematic review and meta-analysis
Creators: name: Alhajj, Mohammed Nasser
name: Halboub, Esam
name: Yacob, Norlela
name: Al-Maweri, Sadeq Ali
name: Ahmad, Siti Fauzza
name: Celebić, Asja
name: Al-Mekhlafi, Hesham M.
name: Salleh, Nosizana Mohd
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2.
title: Production planning process optimization
Creators: name: Szabo, Uwe Pascal
Year: 2009

description: Produktionsautomationssysteme sind komplexe Systeme mit viele Entitäten (Roboter, Transportsysteme usw.) die mannigfaltig aufeinander einwirken und zusammenspielen um das Ziel einer Produktendfertigung zu ermöglichen. Multiagenten-Systeme basierend auf verteilter Kontrolle sind der praktikabelste Ansatz die ansteigende Kompliziertheit solcher Systeme in den Griff zu bekommen und gleichzeitig eine flexible Anpassung des Produktionsautomationssystems an variable Rahmenbedingungen zu gewährleisten (z.B. Änderung von Produktionsstrassen oder die Koordination von Transportelementen). Für solch kritische Produktionsautomationssysteme ist eine Überprüfung aller Schritte im Entwicklungsprozess erforderlich um ein sicher funktionierendes System zu gewährleisten. Qualitätsmessungen zur Sicherstellung der Korrektheit von Systemelemente stellen bei der Zielerreichung daher einen wichtigen Schritt dar. Die Softwaresimulation des Werkstatt-Systems erlaubt sowohl Leistungsmessung einer Systemkonfiguration als auch schnellere und preiswertere Reaktion auf sich ändernde Voraussetzungen. Hinzu kommt, dass die Softwaresimulation von Produktionsautomationssystemen immer mehr einen praktikable Möglichkeit darstellt, um Produktionsvorgänge zu planen und/oder zu optimieren.
description: Production Automation Systems are complex systems. They typically have many entities like robots, transport systems, etc. that interact in complex ways to provide production automation functions like assembly of products. The increasing complexity of these systems makes central control more and more difficult. Therefore systems with distributed control are areas of intense research such as multi-agent systems. Moreover, changing requirements for production automation systems require better system and model flexibility for e.g. easy-to-change workshop layouts or coordination of transportation elements. Meeting all this tasks makes the design of a production automation system a challenge hard to solve for designers and system engineers. For safety-critical systems like production automation systems, verification is required for all steps in the development process. Testing aims at measuring the quality of executable system elements, especially the validity of a configuration and correctness of calculated results. A particular challenge is measurement of non-functional quality requirements such as system performance before the actual hardware system is built. Software simulation of the workshop system would allow both performance measurement of a configuration and faster, cheaper reaction to changing requirements, however the validity of the simulation has to be assured. On top of this, software simulation of production automation systems can get more and more a sufficient part during the production planning and optimization process.
Boosting antitumor drug efficacy with chemically engineered multidomain proteins
Creators: name: Kuan, Seah Ling
name: Fischer, Stephan
name: Hafner, Susanne
name: Wang, Tao
name: Syrovets, Tatiana
name: Liu, Weina
name: Tokura, Yu
name: Ng, David Yuen Wah
name: Riegger, Andreas
name: Förtsch, Christina
name: Jäger, Daniela
name: Barth, Thomas F. E.
name: Simmet, Thomas
name: Barth, Holger
name: Weil, Tanja
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: chemically engineered proteins
subject: combination oncotherapy
subject: supramolecular fusion proteins
subject: targeted delivery
subject: DDC 540 / Chemistry & allied sciences
subject: DDC 620 / Engineering & allied operations
subject: Protein therapeutics (Wiley-VCH)
subject: Targeted drug delivery

description: A facile chemical approach integrating supramolecular chemistry, site-selective protein chemistry, and molecular biology is described to engineer synthetic multidomain protein therapeutics that sensitize cancer cells selectively to significantly enhance antitumor efficacy of existing chemotherapeutics. The desired bioactive entities are assembled via supramolecular interactions at the nanoscale into structurally ordered multiprotein complexes comprising a) multiple copies of the chemically modified cyclic peptide hormone somatostatin for selective targeting and internalization into human A549 lung cancer cells expressing SST-2 receptors and b) a new cysteine mutant of the C3bot1 (C3) enzyme from Clostridium botulinum, a Rho protein inhibitor that affects and influences intracellular Rho-mediated processes like endothelial cell migration and blood vessel formation. The multidomain protein complex, SST3-Avi-C3, retargets C3 enzyme into non-small cell lung A549 cancer cells and exhibits exceptional tumor inhibition at a concentration ≈100-fold lower than the clinically approved antibody bevacizumab (Avastin) in vivo. Notably, SST3-Avi-C3 increases tumor sensitivity to a conventional chemotherapeutic (doxorubicin) in vivo. These findings show that the integrated approach holds vast promise to expand the current repertoire of multidomain protein complexes and can pave the way to important new developments in the area of targeted and combination cancer therapy.
Additional file 1 of Early-life ruminal microbiome-derived indole-3-carboxaldehyde and prostaglandin D2 are effective promoters of rumen development
Creators: name: Sun, Daming
name: Bian, Gaorui
name: Zhang, Kai
name: Liu, Ning
name: Yin, Yuyang
name: Hou, Yuanlong
name: Xie, Fei
name: Zhu, Weiyun
name: Mao, Shengyong
name: Liu, Junhua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Ecology
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health

description: Additional file 1: Supplementary Figures. This additional file contains the supplementary figures (Fig. S1-S9).
title: Методы оптимизации систем
title: Учебное пособие
titleType: Subtitle
Creators: name: Жидкова Н.В.
name:  Мельникова О.Ю.
Publisher: name: Ай Пи Эр Медиа
Year: 2018

description: В настоящем пособии рассматриваются различные экономические задачи математического программирования. В книге излагается теоретическая сторона решения этих задач. Приведены определения, формулы, а также методические указания, необходимые для решения задач; даны решения типовых задач, показаны возможности использования в этих целях MS Excel. Приведены задачи по вариантам для самостоятельного решения и перечень контрольных вопросов. Предназначено для бакалавров, обучающихся по направлению подготовки 38.03.02 «Менеджмент», 38.03.01 «Экономика», 09.03.02 «Информационные системы и технологии», для выполнения практических заданий по курсам «Методы оптимальных решений», «Методы оптимизации» и «Методы оптимизации информационных систем». Соответствует требованиям ФГОС ВО и ОП ВО по данным направлениям подготовки.
description: In this manual discusses the various economic tasks of mathematical programming. The book outlines the theoretical side of these tasks. The definitions, formulas, and guidelines that are necessary for solving problems; the solutions to some typical problems, the possibilities of use of the MS Excel. Given the task of options for independent decisions and checklist. Designed for students studying in the direction of preparation 38.03.02 Management 38.03.01 "Economics" 09.03.02 "Information systems and technologies" for performing practical tasks on the courses "Methods of optimization", "Methods of optimization" and "optimization Methods of information systems". Meets the requirements of the GEF IN the OP and IN the according fields.
title: Уголовно-правовая охрана семьи, прав и свобод несовершеннолетних
title: Учебно-практическое пособие
titleType: Subtitle
Creators: name: Петрова И.А.
Publisher: name: Вузовское образование
Year: 2018

description: В настоящем пособии рассматриваются вопросы, возникающие в связи с совершением преступлений против семьи, посягающих на право и свободы несовершеннолетних. Предметом исследования выступили нормы уголовного законодательства об ответственности за преступления против семьи и несовершеннолетних, а также практика их применения. В издании освещены основные точки зрения, встречающиеся в научной литературе в рамках исследуемых вопросов; дана уголовно-правовая характеристика составов преступлений, предусматривающих уголовную ответственность за преступления, посягающие на нормальные условия жизни семьи, права и свободы несовершеннолетних; выявлены основные проблемы применения нормативно-правовой базы в части исследуемых вопросов на практике; сформулированы предложения по совершенствованию уголовных норм, предусматривающих ответственность за рассматриваемую группу преступлений. Учебно-практическое пособие предназначено для студентов юридических вузов и факультетов, а также аспирантов, специализирующихся по уголовному праву. Пособие будет интересно и полезно практическим работникам, научным работникам, специалистам в сфере правоприменительной деятельности.
description: In this manual addresses issues that arise in connection with the Commission of crimes against the family, would infringe on the rights and freedoms of minors. The subject of study is the norms of criminal legislation on liability for crimes against family and minors, as well as their practical application. The publication highlights the main points of view found in scientific literature within the framework of this study; given criminally-legal characteristic of crimes involving criminal liability for crimes that infringe on the normal conditions of family life, rights and freedoms of minors; the basic problems of application of normative-legal base in the part of the study of issues in practice; suggestions for improving the penal norms providing for liability for the considered group of crimes. Textbook is intended for students of law universities and faculties, and graduate students specializing in criminal law. The guide will be interesting and useful to practitioners, researchers, experts in the field of law enforcement.
title: Nonlinear In-Plane Stability of Heterogeneous Curved Beams under a Concentrated Radial Load at the Crown Point
Creators: name: Kiss, L.
name: G. Szeidl
Publisher: name: Otto von Guericke University Library, Magdeburg, Germany
Year: 2015

description: Technische Mechanik; 35; 1; 1-30; ISSN 2199-9244
description: This paper is devoted to the stability problem of shallow curved beams provided that the beam is made of a heterogeneous material. It is assumed that (a) the radius of curvature is constant and (b) the Young's modulus and Poisson's number depend on the cross-sectional coordinates. We have the following objectives: (1) derivation of a model more accurate than those available in the literature, (2) determination of the critical load assuming that the beam is subjected to a constant radial dead load at the crown point, (3) comparison of the results obtained with solutions valid for homogeneous beams.
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 282 (36. Jg.), Oktober 2006
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: DDC 050 / General serial publications
subject: Universities; Germany; Ulm
subject: Ulm / Universität

description: N/A
PartnerCARE — a psycho-oncological online intervention for partners of patients with cancer: study protocol for a randomised controlled feasibility trial
Creators: name: Bodschwinna, Daniela
name: Lorenz, Inga
name: Bauereiss, Natalie
name: Gündel, Harald
name: Baumeister, Harald
name: Hönig, Klaus
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: caregiver
subject: partner
subject: spouse
subject: distress
subject: caregiver burden
subject: online intervention
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: Cancer
subject: Neoplasms
subject: Caregivers
subject: Spouses
subject: Stress, Psychological
subject: Quality of life
subject: Psycho-Oncology
subject: Telemedicine
subject: Psychosocial support systems
subject: Krebs
subject: Krebskranker
subject: Pflegeperson
subject: Ehegatte
subject: Stress
subject: Lebensqualität
subject: E-Health
subject: Telemedizin
subject: Psychoonkologie

description: Cancer burdens not only the patient but also the partner to a comparable extent. Partners of patients with cancer are highly involved in the caring process and therefore often experience distress and report a low quality of life. Interventions for supporting partners are scarce. Existing ones are rarely used by partners because they are often time-consuming per se and offer only limited flexibility with regard to schedule and location. The online intervention PartnerCARE has been developed on the basis of caregiver needs and consists of six consecutive sessions and four optional sessions, which are all guided by an e-coach. The study aims to evaluate feasibility and acceptance of the online intervention PartnerCARE and the related trial process. In addition, first insights of the putative efficacy of PartnerCARE should be gained.
Evaluation of eosinophilic cationic protein as a marker of alveolar and cystic echinococcosis
Creators: name: Hotz, Julian Frederic
name: Kaczirek, Klaus
name: Stremitzer, Stefan
name: Waneck, Fredrik
name: Auer, Herbert
name: Perkmann, Thomas
name: Kussmann, Manuel
name: Bauer, Philipp Karl
name: Chen, Rui-Yang
name: Kriz, Richard
name: Burgmann, Heinz
name: Ramharter, Michael
name: Lagler, Heimo
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: eosinophilic cationic protein
subject: routine marker
subject: DDC 610 / Medicine & health
subject: Echinococcosis
subject: Biomarkers
subject: Zystische Echinokokkose
subject: Biomarker

description: Echinococcosis is a neglected zoonotic disease and a worldwide public health problem caused by infection with the larval stages of taeniid cestodes of the genus Echinococcus. In vitro studies have demonstrated a protoscolecidal effect of eosinophilic cationic protein (ECP), a granule protein of eosinophilic granulocytes, against E. granulosus. Therefore, the main objective of this study was to evaluate ECP as a biomarker in the treatment of alveolar echinococcosis (AE) and cystic echinococcosis (CE). Data were collected retrospectively from the Vienna Echinococcosis Cohort over 7 years until December 2020. Altogether, 32 patients (16 AE and 16 CE) were included. In the selected patients, serum ECP values were compared before and after the beginning of an operative and/or benzimidazole (BMZ) therapy. Mean ECP serum levels before intervention were significantly (p < 0.05) elevated at 34.0 ± 22.9 μg/L in AE patients and at 38.6 ± 19.9 μg/L in CE patients compared to the control group. After the intervention, mean ECP levels decreased significantly (p < 0.05) to 20.4 ± 14.6 μg/L in AE patients and to 22.4 ± 8.3 μg/L in CE patients. Furthermore, ECP showed a significant (p < 0.05) correlation of k = 0.56 with PET–CTI. Based on the significant decrease after operative and/or BMZ treatment and the correlation with clinical markers such as PET–CTI, it is recommended to investigate ECP more intensively as a marker of AE and CE in prospective studies with larger cohorts.
Assessing CCTV in Preventing and Reducing Property Crime
Creators: name: Lang, Kay
name: Sanford, Justin
name: Murtagh, Christopher
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Closed-circuit television (CCTV) cameras are commonly used to reduce crime in public spaces through detection and deterrence. While most research focuses on large cities, this study examines CCTV’s impact in a small city, providing insights into similar communities. The Anniston Police Department (APD) with a Smart Policing Initiative (SPI) grant sought to lower Part 1 property crime using a quasi-experimental design and Geographical Information Systems (GIS) crime mapping to identify hot spots. We analyzed 18 months of pre- and post-intervention data using weighted displacement quotient and weighted displacement difference. Aggregate counts of burglary, motor vehicle theft (MVT), and theft decreased by 8.5% in the three main hot spots and buffer zones, while control areas experienced a 13.4% increase. However, reductions varied by area and crime type, suggesting that CCTV may be more effective in specific environments. None of the findings reached statistical significance, likely due to low crime volumes; higher crime volumes could produce different results. Two years later, the APD has maintained and expanded its CCTV system, utilizing it as an investigative tool for solving crimes and supporting prosecutions. This indicates that CCTV could be beneficial for small police departments in addressing crime.
sj-pdf-1-smm-10.1177_0962280220909986 - Supplemental material for Quantile regression for incomplete longitudinal data with selection by death
Creators: name: Jacqmin-Gadda, Hélène
name: Rouanet, Anaïs
name: Mba, Robert D
name: Philipps, Viviane
name: Dartigues, Jean-François
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-smm-10.1177_0962280220909986 for Quantile regression for incomplete longitudinal data with selection by death by Hélène Jacqmin-Gadda, Anaïs Rouanet, Robert D Mba, Viviane Philipps and Jean-François Dartigues in Statistical Methods in Medical Research
Datenflussvarianten in Prozessmodellen: Szenarien, Herausforderungen, Ansätze
Creators: name: Kaiser, Stefanie
name: Reichert, Manfred
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Prozessmodellierung
subject: Prozessvarianten
subject: DDC 004 / Data processing & computer science
subject: Data flow computing
subject: Adaptives Prozessmodell
subject: Datenfluss

description: Die geeignete Unterstützung von Geschäftsprozessen gewinnt durch die Abkehr vom funktionalen betrieblichen Aufbau hin zu prozessorientierten Organisationsstrukturen zunehmend an Bedeutung. Dabei wurde erkannt, dass ein bestimmter Prozesstyp oftmals nicht nur durch ein einziges Prozessmodell beschrieben werden kann, sondern dass abhängig vom Anwendungskontext unterschiedliche Prozessvarianten existieren. Die Gründe, mehrere Prozessvarianten gleichzeitig zu unterstützen und nicht auf einer einzigen Definition zu beharren, sind vielfältig. So müssen z.B. bei internationalen Unternehmen die Prozesse an die Rahmenbedingungen des jeweiligen Landes (z.B. gesetzliche Regularien) oder eine prozessorientierte Software für den jeweiligen Anwendungskontext angepasst werden. Der Umgang Prozessvarianten wurde in verschiedenen Forschungsarbeiten thematisiert, wobei diese mehrheitlich auf die Kontrollflussperspektive fokussieren. Die Datenflussperspektive ist im Zusammenhang mit Prozessvarianten noch wenig beachtet. Aus diesem Grund soll im Folgenden untersucht werden, wie das Management von Prozessvarianten unter dem Gesichtspunkt eines modifizierten Datenflusses gestaltet werden sollte. Es wird analysiert, unter welchen Bedingungen der Datenfluss eine Änderung erfährt und welchen Anforderungen ein Prozessvariantenmodellierungsansatz genügen muss.
Additional file 9 of Early-life ruminal microbiome-derived indole-3-carboxaldehyde and prostaglandin D2 are effective promoters of rumen development
Creators: name: Sun, Daming
name: Bian, Gaorui
name: Zhang, Kai
name: Liu, Ning
name: Yin, Yuyang
name: Hou, Yuanlong
name: Xie, Fei
name: Zhu, Weiyun
name: Mao, Shengyong
name: Liu, Junhua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Ecology
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health

description: Additional file 9. Animal welfare.
Drosophila enhancer adult bristle expression assay using UAS sv-RNAi
Creators: name: Luecke, David
Publisher: name: Zenodo
Year: 2021

description: Data from manuscript "Sex-specific evolution of a Drosophila sensory system via interacting cis- and trans-regulatory changes" by D Luecke, G Rice, and A Kopp. This study examines the regulation of expression for the chemosensory bristle specifier gene Pox neuro, which has expanded expression into ancestrally mechanosensory bristles in male D. prolongata. Flourescent assays show qualitativetly expanded expression driven by the D. prolongata allele relative to enhancers from sister species in the developing pupal leg. Adult bristle disruption assays using shavenoid RNAi show quantitative expression expansion by the D. prolongata allele into specific mechanosensory bristles on the dorso-anterior leg of the first tarsi.
description: Bristle identities are based on the included first tarsus diagram, modified from Tokunagu 1962. Missing values represent intact bristles, and are treated as such (1s) by the accompanying R script.
description: Pox neuro enhacer regions were cloned into Gal4 reporter vector pBPGUw and inserted site-specifically into the attP2 docking site. Homozygous reporter-Gal4 flies were crossed to UAS-dcr2; UAS-svRNAi flies. T1 legs from the F1 of this cross were mounted in PVA clearing media and examined under light microscopy. Individual bristles were scored as 0 for missing, 0.5 for truncated, and 1 for intact. Comparisons between number of effected bristle per species enhancer allele were done by pairwise t test, with bonferonni correction for multiple tests.
Supplemental Material - What distinguishes radical right welfare chauvinism? Excluding different migrant groups from the welfare state
Creators: name: Chueri, Juliana
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 160512 Social Policy

description: Supplemental Material for What distinguishes radical right welfare chauvinism? Excluding different migrant groups from the welfare state by Juliana Chueri in Journal of European Social Policy
Geophysical and geochemical evidence for a new mafic magmatic province within the Northwest Shelf of Australia: Supplementary material
Creators: name: Yule, Christopher
name: Spandler, Carl
Publisher: name: Zenodo
Year: 2022

description: Buried magmatic provinces are rarely identified and difficult to classify. The Northwest Shelf of Australia contains large volumes of potentially interconnected mafic igneous material across several sedimentary basins. However, limited study and a lack of surface exposure have prevented detailed description and classification of these rocks. In this study, the distribution and composition of these mafic igneous rocks is described using an integrated geophysical and geochemical approach, which included over 10,000 km of 2D historical seismic data, well log data and chemical analysis of samples from 14 wells across the Browse, Roebuck, Canning and North Carnarvon basins. Using this combined dataset, we demonstrate interconnectivity of buried mafic igneous rocks across the Northwest Shelf and calculate for these mafic rocks a total surface area exceeding 280,000 km2 and a cumulative minimum volume of ~140,000 km3. Petrology and geochemistry of samples indicate they are basaltic and doleritic with alkaline and sub-alkaline compositions and formed in a continental rift setting. Collectively, the igneous rocks meet the criteria for classification as a mafic magmatic province (MMP) and closely match the criteria required for classification as a large igneous province (LIP). The interconnected mafic igneous rocks found across the Northwest Shelf of Australia are here formally defined as an MMP. Emplacement of the Northwest Shelf MMP may represent hotspot magmatism that could have initiated rifting of the Cimmerian Block from NW Australia near the end Permian, and may have broad implications for petroleum prospectivity, CO2 sequestration and new resource opportunities in the Northwest Shelf.