cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Teachers' Supervisory Preference: Basis for Rethinking Instructional Supervision Practice (Abstract)
Creators: name: Bada Basilio, Manolito
Publisher: name: unknown
Year: 2024
Subjects: subject: Teaching
subject: School supervision
subject: Mentoring
subject: Research
subject: Perspective--Study and teaching
subject: Supervisors
subject: Teacher development
subject: Classroom management
subject: Teachers
subject: Education

description: This paper aimed to find out the preferences of teachers in terms of instructional supervision types, thus serving as the basis for rethinking instructional supervision practice by all concerned. This descriptive research involved 17 teachers of a national high school in Botolan, Zambales, Philippines. The data were gathered through a survey questionnaire. Teachers' most preferred type of supervision is mentoring, followed by peer coaching or collegial consultation, directed or clinical supervision, and administrative monitoring or walkthroughs. Teachers acknowledge that their supervisory preference helps them improve their classroom instructional practice. Responses disclose that teachers become "better" by learning from the sharing of other teachers' perceptions, experiences, and ideas, as well as by being open to understanding and knowing more about the teaching and learning process. Teachers want to be treated as "professionals," and they need to be appreciated, as this boosts their morale and encourages them to even do better and strive for the attainment of their best potential as classroom managers. In light of the conclusions of the study, recommendations, implications, and suggestions for further research are given.

Keywords: supervisory preference, teachers, descriptive research, mentoring, improved instruction
Additional file 13 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 13: Supplementary Figure S7. IGU inhibits Th1, Th2 and Th17 cell differentiation.
Experimental and numerical investigation of film cooling jet on a flat plate wind tunnel
Creators: name: ROUINA, Samaneh
Publisher: name: Universit� degli studi di Bergamo
Year: 2018

description: An experimental and numerical study was conducted to investigate the unsteady behavior of film cooling jet for two different hole geometries on a flat plate wind tunnel. The numerical part was devoted to the assessment of different turbulence models to get the best prediction of both aerodynamic and thermal performance with a conventional RANS approach. The investigated hole geometries include a row of three cylindrical holes and a row of three fan-shaped holes with an inclination of 30 degrees with respect to the flat plate. Tests have been carried out at low speed and low inlet turbulence intensity level, with blowing ratios varied in the range of 0.5?1.5, and 1-2 for cylindrical and fan-shaped holes, respectively. Aerodynamic investigations have been performed by means of Laser Doppler Velocimetry (LDV), Particle Image Velocimetry (PIV), and Hotwire Anemometry (HW). LDV was used to study the boundary layer behavior just downstream of the holes. A high- resolution PIV system was used for flow visualization and flow field measurement to investigate the unsteady mixing process taking place between the coolant and main flow. Furthermore, HW has been used to measure velocity components in a vertical-lateral plane. For thermal measurements, the binary PSP technique was used to measure adiabatic film cooling effectiveness. Results obtained from aerothermal experiments show that by expanding the exit of the cooling hole, the penetration of the cooling jet is significantly reduced relative to the cylindrical hole, thereby providing a better coverage over the flat plate even at high blowing ratios. Furthermore, the effect of density ratio was investigated using CO2 as a foreign gas. In the same BR, the jet with a greater density ratio provides better film protection over the flat plate surface. Finally, detailed experimental data was compared with three turbulence models, which are RKE, SST KW, and RSM turbulence models, in the state-of-art CFD code STAR-CCM+, result in selecting SST KW and RSM turbulence models for cylindrical and fan-shaped holes, respectively.
The Mother of All Pandemics The State of Black Death Research in the Era of Covid-19 - Bibliography, created 05152020; latest update 03152024
Creators: name: H. Green, Monica
Publisher: name: unknown
Year: 2024
Subjects: subject: Medicine
subject: History
subject: Middle Ages
subject: Genetics
subject: FOS: Biological sciences
subject: Pandemics

description: The present bibliography was originally prepared for a webinar sponsored by the Medieval Academy of America in May 2020. The present version includes all citations added as of 15 March 2024. The Bibliography covers the Black Death as traditionally defined (the plague pandemic that struck western Eurasia and North Africa between 1346 and 1353) but sets it into new narratives of the early phases (13th through 15th centuries) of the Second Plague Pandemic, which touched major parts of Afro-Eurasia. The Bibliography will continue to be updated as a Google Doc, which can be found at this address: https://docs.google.com/document/d/1x0D_dwyAwp9xi9sMCW5UvpGfEVH5J2ZA/edit?usp=sharing&ouid=104263744463668175127&rtpof=true&sd=true.
Solution Space Modeling for Robotic Systems
Creators: name: Arunkumar Ramaswamy
name: Monsuez, Bruno
name: Tapus, Adriana
Publisher: name: Universit� degli studi di Bergamo
Year: 2014

description: Motivated from the experience of developing a lidar based vehicle tracking system, a model-based approach for specifying the solution space of robotic system is proposed in this paper. Solution space modeling can expand the design space, help finding the best possible solution, identify variation points, and also permit to perform context based run-time adaptation of the system. Models based on the proposed Solution Space Modeling Language (SSML) can help in system level reasoning, making tradeoffs, documenting decisions, and comparing them based on functional and non-functional properties, and can act as an artifact for formally proving and validating the final implementation.
Additional file 2 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 2: Supplementary Table S2. PCR primers used in this study.
The Mother of All Pandemics The State of Black Death Research in the Era of Covid-19 - Bibliography, created 05152020; latest update 03152024
Creators: name: H. Green, Monica
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: History
subject: Middle Ages
subject: Pandemics

description: The present bibliography was originally prepared for a webinar sponsored by the Medieval Academy of America in May 2020. The present version includes all citations added as of 15 March 2024. The Bibliography covers the Black Death as traditionally defined (the plague pandemic that struck western Eurasia and North Africa between 1346 and 1353) but sets it into new narratives of the early phases (13th through 15th centuries) of the Second Plague Pandemic, which touched major parts of Afro-Eurasia. The Bibliography will continue to be updated as a Google Doc, which can be found at this address: https://docs.google.com/document/d/1x0D_dwyAwp9xi9sMCW5UvpGfEVH5J2ZA/edit?usp=sharing&ouid=104263744463668175127&rtpof=true&sd=true.
What Would it Mean to Build a Community of Shalom for Those Living with Eating Disorders?
Creators: name: Naomi Douglas, Joanna
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Psychic trauma
subject: Theology
subject: Pastoral theology
subject: Eating disorders

description: In many ways, the making and sharing of meals is a significant portion of the fellowship and community of the church, a portion of faith-driven life so integral that “food and religious practice are intimately connected in the Judeo-Christian tradition.”  Christianity has at its heart a vision of community where “a commitment to eating together, to sharing, in various symbolic degrees, the body and blood of Jesus Christ”  is one of our most sacred and fundamental sacraments. Christianity has argued that this image of community has also in many ways been exampled to us by Jesus in His life, the last supper and by the early Christians in Acts. Therefore, many Christians attempting to live out this image of community do so by regularly making food and eating together a central aspect of their interpretation of what community means within their life. This interpretation of community is growing increasingly common among Christians, and food has become a central and largely understood to be a positive experience of religious traditions. However, this is something which needs to be explored deeply,  particularly in light of the ever growing number of people living with distorted eating.
Additional file 1 of Effect of workplace violence on health workers injuries and workplace absenteeism in Bangladesh
Creators: name: Shahjalal, Md.
name: Parvez Mosharaf, Md.
name: Mahumud, Rashidul Alam
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Workplace injury and absenteeism due to WPV survey questions used in the current analysis.
Early Portuguese recordings for The Gramophone Company (1900—1908) and the establishment of a phonographic market in Portugal
Creators: name: Silva, Joao
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Sound recordings
subject: Sound recording industry
subject: Popular music
subject: Popular music genres

description: My article strives to study phonography in Portugal between the 1900 recording sessions for The Gramophone Company and the company’s first significant Portuguese catalogue, printed in December 1908. I aim to trace the transformations undertaken in the discs and repertoires along with their segmentation during the first decade of Portuguese phonography, with the establishment of a phonographic market in the country.
Additional file 8 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 8: Supplementary Figure S2. Peripheral T cell subsets in IGU-treated pSS patients.
UN RIVOLUZIONARIO DURANTE L'ANTICO REGIME: JACQUES-VINCENT DELACROIX (1766-1789).
Creators: name: BORRE', MATTEO
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: The research aims to provide a first introductory look to the life and thought of Jacques-Vincent Delacroix (1743-1831), Avocat au Parlement in Paris during the Ancien R�gime, a well-known professor of Public law at the Lyc�e from 1789 to 1793, Judge in Versailles since 1795 and author of a real bestsellers of the Revolutionary Era, the ?Constitutions des principaux �tats de l?Europe et des �tats-Unis?.
Lawyer and man of letters who lived between the reign of Louis XV and the French Revolution of 1830, Delacroix has been both a prolific writer and an eye-witness of the political and cultural changes who finally lead to the creation of the Modern France.
So, the life of Delacroix became a case of study due to the fact that it helps to understand better the many ups-and-downs and the late successes of an entire generation, who asserted itself only at the end of the Ancien R�gime and slowly became the trait d?union between the revolutionaries of 1789 and the men who arose again in defense of freedom in 1830.
This study, who wants also be a first contribution to a future fulfillment of a more specific political biography of Delacroix, takes shape as an interdisciplinary approach to his life ? where the first part is a description of the put on trial of Delacroix in front of the Revolutionary Tribunal in 1795 and a report of both the contemporary and the historical debate that surrounded the event, the second one is a complete and revisited biographic profile, and the third one is a reconstruction of his carrier during the Ancien R�gime ? that finally lead to explain how Delacroix came closer to the revolutionary line-up and what are the origins of his following faithful, but always critical, acceptation of the ideals of 1789.
Additional file 16 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 16: Supplementary Figure S10. IGU suppresses Tfh cell-facilitated B cell differentiation.
sj-pdf-1-cph-10.1177_17151635211018254 – Supplemental material for A survey of Alberta pharmacists’ attitudes, comfort and perceived barriers to a community-based naloxone program
Creators: name: Nowlan, Sarah-Emily
name: MacKinnon, Neil J.
name: Hincapie, Ana
name: Tachuk, Matt
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-cph-10.1177_17151635211018254 for A survey of Alberta pharmacists’ attitudes, comfort and perceived barriers to a community-based naloxone program by Sarah-Emily Nowlan, Neil J. MacKinnon, Ana Hincapie and Matt Tachuk in Canadian Pharmacists Journal / Revue des Pharmaciens du Canada
Kosovo and Albania, a Special Relationship: Retrospectives and Challenges Toward the Future
Creators: name: Krasniqi, Afrim
name: Lika, Liridon
Publisher: name: Routledge
Year: 2023

description: Over 30 years, Albania's relations with Kosovo have reflected a continuous interplay of ever-changing political realities, intrinsically linked to the geopolitical developments in the Balkans and in the world and geared to a still incomplete process of transition of both countries from (merely) patriotic rhetoric towards each-other to a more sensible, down to earth discourse primarily focused on institutional cooperation. Because of its history and symbolic value, Albania played a special role throughout the phases of liberation, state-building, independence and recognition of Kosovo. Nonetheless, more often than not, Kosovo and Albania ran on parallel agendas built on different priorities.
This chapter analyses institutional relations and institutional acts between Albania and Kosovo. It does so based on various sources, by drawing mostly on the official documentation and resources of the Republic of Albania and the Republic of Kosovo, and on the informal documentation and notes made by former senior officials, media, in addition to reports and academic literature. The chapter concludes that the balance of state acts and the records of cooperation between the two countries, despite their mutual achievements, fails to fulfil the expectations of the public of Kosovo and Albania, as both countries remain widely unable to meet the political promises and needs of their states and societies. Milestone achievements to date have come into being mainly because of the coincidence of the interests of Kosovo and Albania with those of their key Western partners. The Kosovo-Albania relations have still a long way to go in terms of establishing a functional interstate relationship to overcome the highly fragmented cooperation patterns built around the personal preferences of their current political elites.

Keywords: Albania, Kosovo, strategic relations, agreements, integration, nationality.
Institucioni i Presidentit të Republikës: Problematika rreth kornizës kushtetuese të formatimit dhe kompetencave të tij
Creators: name: Krasniqi, Afrim
Publisher: name: Humanities Commons
Year: 2018

description: Kuadri kushtetues mbi Presidentin dhe legjislacioni mbështetës i kompetencave rreth tij, kanë qenë dhe mbeten çështje diskutimi politik dhe shpesh, edhe të interpretimit të Gjykatës Kushtetuese. Në gjykimin e saj kanë kaluar çështjet e raporteve President – Kuvend në emërimin e gjyqtarëve të Gjykatave të Larta dhe Kushtetuese, çështje të funksionimit të KLD dhe raportit me ekzekutivin, çështje të kompetencave të Presidentit në fushën e mbrojtjes, të trajtimit të dekreteve presidenciale për emërime të rëndësishme institucionale, etj. Mungesa e një ligji organik të institucionit, si dhe paqartësitë apo interpretimet ligjore që lidhen me ushtrimin e kompetencave, e kanë shndërruar institucionin e Presidentit, në një prej subjekteve kushtetuese më të përfshira në axhendën politike, publike dhe institucionale.  Ky punim merr përsipër të trajtojnë aspekte më të gjera të kompetencave presidenciale, të pozitës së Presidentit në kuadrin kushtetues dhe ligjor dhe çështje, të cilat për shkak të mënyrës së formulimit kushtetues apo mungesave të formulimit, mund të shërbejnë si shkak për debate të reja kushtetues e politike mbi institucionin e Presidentit. Ai evidenton çështje e raste ku sugjerohen propozime konkrete për ndërhyrje kushtetuese dhe ligjore. Studimi bazohet në eksperiencën shqiptare 24 vjeçare të funksionit të Institucionit të Presidentit, në eksperiencat e njëjta rajonale, në vendimet interpretuese të Gjykatës Kushtetuese, si dhe në literaturën ende të pakët ligjore dhe politike mbi këtë institucion.  Fjalë kyçe: Presidenti, Kushtetuta, Kompetencat presidenciale, Parlamenti, ligji organik
THREATS ON REAL, EMULATED AND VIRTUALIZED INTEL X86 MACHINE CODE EXECUTION
Creators: name: FRESI ROGLIA, GIAMPAOLO
Publisher: name: Universit� degli Studi di Milano
Year: 2011

description: Cybercriminals have all the interest in not being detected while perpetrating their intentions. Impeding such threats to spread has become of valuable importance. This goal can be achieved working on the threat vectors cybercriminals use or directly on the threat once identified.
Among threat vectors we can cite application software vulnerabilities which can be abused by malware and malicious users to gain access to systems and confidential data. To be able to impede exploitation of such vulnerabilities, security specialists need to be aware of attack techniques used by malware and malicious users for to be able to design and implement effective protection techniques.
For identifying threats, it is of vital importance to use effective analysis tools which expose no weaknesses to malware authors giving them the chance to evade detection.
This dissertation presents two approaches for testing CPU emulators and system virtual machines which represent a fundamental component of dynamic malware analysis.
These testing methodologies can be used to identify behavioural differences between real and emulated hardware. Differences exploitable by malware authors to detect emulation and hide their malicious behaviour.
This dissertation also presents a new exploitation technique against memory error vulnerabilities able to circumvent widely adopted protection strategies like W^X and ASLR and the related countermeasure to impede exploitation.
Additional file 1 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 1: Supplementary Table S1. Demographic characteristics of pSS cohort.
Die politischen Parteien Albaniens und Europa
Creators: name: Krasniqi, Afrim
Publisher: name: Franz Steiner Verlag
Year: 2018

description: Zwischen dem Begriff der politischen Stabilität und dem Konzept der funktionalen Demokratie (beide Themen sind dominant in der EU-Wahrnehmung albanischer Bürger und in ihren Erwartungen auf die EU-Integration) muss eine effektive Bindung geschaffen werden. Das bedarf Mechanismen transparenter Entscheidungsfindung, Beratung und weitere Maßnahmen, damit es möglich gemacht werden kann, dass die Bürger vom Integrationsprozess profitieren können, anstelle ihrer alten politischen Eliten.

Die neue Generation der albanischen Bürger hat die kommunistische Epoche nicht miterlebt. Sie hat, weder ihre Isolation, noch ihre extreme Armut durchhalten müssen. Ihr wurden auch viele negativen Erscheinungen, die in den frühen 90er Jahre stattfanden, erspart. Die jungen Albaner von heute haben eindeutig höhere Lebenserwartungen und größere Ansprüche auf eine bessere Lebensqualität und dazu können sie pragmatischer in ihren politischen Entscheidungen sein als die sowie idealistisch als auch parteilich gesinnten Jugendlichen der 90er. Für diese Altersgruppe sind nur Integrationsslogans einfach unzulänglich. Ihre Ansprüche sind konkret, und ihre Erwartungen werden durch das Angebot der traditionellen politischen Parteien nicht erfüllt. Wenn diese Erwartungen nicht ernsthaft in Betracht gezogen werden, dann können einige von ihnen nach neuen Wegen suchen, einschließlich der neuen sozialen Bewegungen, der nationalistischen Angebote, und der religiösen oder kulturellen Identitäten. Ihre Probleme bedürfen einer tieferen, komplexeren, und langfristigen Einsicht als zurzeit der Fall ist. Für Albanien, wie für alle Länder der Region, welche dieselbe Problematik teilen, bleibt das eine große Herausforderung.
Impfnebenwirkungen bei Kindern und Jugendlichen. Ergebnisse des Kinder- und Jugendgesundheitssurveys
Creators: name: Poethko-Müller, Christina
name: Atzpodien, Karen
name: Schmitz, Roma
name: Schlaud, Martin
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2011
Subjects: subject: Gesundheitssurvey
subject: Jugendliche
subject: Kinder
subject: KiGGS
subject: Impfungen
subject: Nebenwirkungen
subject: Adolescents
subject: Vaccination
subject: Children
subject: Health surveys
subject: Suspected adverse reactions
subject: 610 Medizin

description: Die Studiendesigns und Instrumente zur Überwachung der Impfstoffsicherheit haben alle Stärken und Schwächen, sodass zu diesem Zweck Daten aus mehreren Quellen genutzt werden sollten. Grundlage für entsprechende Datensammlungen sind unter anderem Selbstangaben von Patienten über mögliche Nebenwirkungen. Bisher ist aber wenig über die Faktoren bekannt, die beeinflussen, ob Personen Impfnebenwirkungen angeben beziehungsweise berichten. Von 2003 bis 2006 wurden im repräsentativen Kinder- und Jugendgesundheitssurvey (KiGGS) von insgesamt 17.641 Probanden im Alter bis zu 17 Jahren Daten zu soziodemografischen Merkmalen, verabreichten Impfstoffen, zum Impfzeitpunkt und zu schlecht vertragenen Impfungen erhoben und Prädiktoren für elternberichtete Impfnebenwirkungen durch uni- und multivariate Analysen ermittelt. Leben in den alten Bundesländern (OR 1,61; 95%-KI 1,08–2,39), ein positiver CSHCN (Cildren with Special Health Care Needs)-Screener (OR 1,49; 95%-KI 1,08–2,04) und eine kritische elterliche Impfeinstellung (OR 3,29; 95%-KI 2,28–4,75) waren unabhängig voneinander mit einer höheren Wahrscheinlichkeit verbunden, dass Eltern Impfnebenwirkungen in der Befragung berichteten. Die Ergebnisse deuten darauf hin, dass die elterliche Wahrnehmung und Bewertung von Impfnebenwirkungen sowie ihre allgemeine Einstellung zu Impfungen die Angaben zu möglichen Nebenwirkungen beeinflussen könnte.
description: Each method to monitor vaccine safety has strengths and limitations. Therefore, vaccine safety monitoring should rely on different types of data sources. Methods commonly rely on patient-reported adverse reactions. Little is, however, known about factors that may affect the probability with which patients report adverse reactions to vaccines. From 2003–2006, the representative National Health Interview and Examination Survey for Children and Adolescents (“Kinder- und Jugendgesundheitssurvey”, KiGGS) retrospectively collected information about vaccines, vaccination dates, and suspected vaccine related adverse reactions from a total of 17,641 participants (
THE ROLE OF EZH2 IN B CELL DEVELOPMENT AND ADAPTIVE IMMUNITY
Creators: name: CAGANOVA, MARIETA
Publisher: name: Universit� degli Studi di Milano
Year: 2012

description: Polycomb group (PcG) proteins are epigenetic modifiers that act as transcriptional repressors modulating chromatin accessibility of target genes. Methylation on lysine-27 of histone H3 (H3K27me3) catalyzed by the PcG protein Ezh2 is a bona fide epigenetic mark linked to lineage specification and identity.
Analyses on PcG mutant mice have revealed an essential role of PcG proteins in haematopoiesis. In the B cell compartment, Ezh2 is expressed in progenitor B cells and is strongly induced upon recruitment of na�ve B cells into the germinal center (GC) reaction, during a T cell dependent immune response. Using a conditional gene targeting approach in vivo, we addressed the effects of Ezh2 inactivation on GC B cell responses, terminal differentiation, memory B cell generation and function.
Conditional inactivation of Ezh2 in GC B cells caused a significant reduction in numbers and frequency of GC B cells. Loss of Ezh2 promoted a significant increase in the fraction of GC B cells undergoing apoptosis.
As a result of the impaired GC reaction, serum titers of antigen-specific, class-switched antibodies were significantly decreased and formation of memory B cells significantly impaired in mutant mice. Instead, mutant GC B cells showed premature onset of terminal differentiation, as assessed by the induction of genes coding for the master regulators of plasma cell differentiation Prdm1, Irf4 and Xbp1.
In this work we provide evidence that sets the ground for a model where Ezh2 together with GC master regulator Bcl6 supports GC B cell identity and function.
sj-pdf-1-nms-10.1177_14614448211021071 – Supplemental material for Public knowledge of alternative media in times of algorithmically personalized news
Creators: name: Klawier, Tilman
name: Prochazka, Fabian
name: Schweiger, Wolfgang
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, sj-pdf-1-nms-10.1177_14614448211021071 for Public knowledge of alternative media in times of algorithmically personalized news by Tilman Klawier, Fabian Prochazka and Wolfgang Schweiger in New Media & Society
Additional file 7 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 7: Supplementary Figure S1. Gating strategy of peripheral T cells and B cells.
Multiscale modeling of delamination fracture in multilayered structures
Creators: name: DARBAN, HOSSEIN
Publisher: name: Universit� degli studi di Genova
Year: 2018

description: In the recent years, there has been increased interest in using multilayered structures in the construction of mechanical devices and vehicles, such as turbines, wind-blades, aircrafts or ships. These structures are often subjected to severe mechanical loads and a wide range of operational temperatures. Under such loading conditions, the stresses in multilayered structures may exceed the elastic limit, and delaminations and debonds may form and propagate as a consequence of the high interfacial tractions caused by the inhomogeneous material structure. To design layered systems and define their load-bearing capacity and life, accurate understanding of their mechanical behavior in the elastic and post-elastic regimes is needed.
Second External Quality Assurance Study for the Serological Diagnosis of Hantaviruses in Europe
Creators: name: Escadafal, Camille
name: Avšič-Županc, Tatjana
name: Vapalahti, Olli
name: Niklasson, Bo
name: Teichmann, Anette
name: Niedrig, Matthias
name: Mantke, Oliver Donoso
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2012
Subjects: subject: Humans
subject: Serologic Tests/standards
subject: Hantavirus Infections/diagnosis
subject: Immunoglobulin M/blood
subject: Europe
subject: International Cooperation
subject: Antibodies Viral/blood
subject: Quality Assurance Health Care/methods
subject: 610 Medizin

description: Hantaviruses are endemic throughout the world and hosted by rodents and insectivores. Two human zoonoses, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS), are caused by hantaviruses and case fatality rates have reached 12% for HFRS and 50% for HPS in some outbreaks. Symptomatic hantavirus infections in Europe are summarised as HFRS mainly due to Puumala, Dobrava-Belgrade and Saaremaa virus. While HFRS has an overall low incidence in Europe, the number of cases varies from 100 per year in all Eastern and Southern Europe up to 1,000 per year only in Finland. To assess the quality of hantavirus diagnostics, the European Network for the Diagnostics of ‘‘Imported’’ Viral Diseases (ENIVD) organised a first external quality assurance (EQA) in 2002. The purpose of this second EQA study is to collect updated information on the efficiency and accurateness of hantavirus serological methods applied by expert laboratories. A serum panel of 14 samples was sent to 28 participants in Europe of which 27 sent results. Performance in hantavirus diagnosis varied not only on the method used but also on the laboratories and the subclass of antibodies tested. Commercial and in-house assays performed almost equally. Enzyme immunoassays were mainly used but did not show the best performances while immunoblot assays were the less employed and showed overall better performances. IgM antibodies were not detected in 61% of the positive IgM samples and IgM detection was not performed by 7% of the laboratories indicating a risk of overlooking acute infections in patients. Uneven performances using the same method is indicating that there is still a need for improving testing conditions and standardizing protocols.
Ay sining ideolohiya? sinaunang panahon sining - simbolismo at lipunan - Indonesian cave painting ng Sulawesi warty pig na itinayo noong 45,500 taon na ang nakalipas, bago ang cave painting sa France-Spain sa pamamagitan ng dekada + at Neanderthal - K Arm
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2024
Subjects: subject: Ideology
subject: Symbolism in art
subject: Prehistoric animals in art
subject: Tools, Prehistoric
subject: Indigenous peoples
subject: Art, Prehistoric
subject: Subconsciousness
subject: Prehistoric peoples
subject: Jungian psychology

description: The Case For God, binuksan ni Karen Armstrong ang kanyang libro sa pagtalakay sa 300 plus caves sa Southern France at Northern Spain na may kamangha-manghang artistikong 'prehistoric' cave paintings ng mga prehistoric na hayop na marami sa kanila ay wala na ngayon, ang ilan ay dating sa 30,000 taon na ang nakalipas. "Sa kabuuan ay may mga anim na raang fresco at labinlimang daang mga ukit sa Lascaux labyrinth. Mayroong malakas na umuungol na itim na lalaki, isang tumatalon na baka, at isang prusisyon ng mga kabayo na gumagalaw sa kabilang direksyon. Sa pasukan sa isa pang mahabang daanan na kilala bilang Nave, isang frieze ng eleganteng usa ang ipininta sa itaas ng Preamble: Ang pilosopo, Susanne K. Langer, sa kanyang artikulo, The Cultural Importance of the Arts. Itinatampok ni Langer ang aspeto ng sining bilang isang banayad at walang malay na impluwensya at puwersa sa lipunan at kultura. "Ang bawat kultura ay bubuo ng ilang uri ng sining na kasingtiyak ng pagbuo ng wika. Ang ilang mga primitive na kultura ay walang tunay na mitolohiya o relihiyon, ngunit lahat ay may ilang sining-sayaw, kanta, disenyo (kung minsan ay sa mga kasangkapan lamang o sa katawan ng tao). Sayaw, higit sa lahat, tila ito ang pinakalumang sining na may paliwanag.....
Ay sining ideolohiya? sinaunang panahon sining - simbolismo at lipunan - Indonesian cave painting ng Sulawesi warty pig na itinayo noong 45,500 taon na ang nakalipas, bago ang cave painting sa France-Spain sa pamamagitan ng dekada + at Neanderthal - K Arm
Creators: name: Peck Jr, Charles
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Indigenous peoples
subject: Prehistoric peoples
subject: Prehistoric animals in art
subject: Art, Prehistoric
subject: Tools, Prehistoric
subject: Ideology
subject: Symbolism in art
subject: Subconsciousness
subject: Jungian psychology

description: The Case For God, binuksan ni Karen Armstrong ang kanyang libro sa pagtalakay sa 300 plus caves sa Southern France at Northern Spain na may kamangha-manghang artistikong 'prehistoric' cave paintings ng mga prehistoric na hayop na marami sa kanila ay wala na ngayon, ang ilan ay dating sa 30,000 taon na ang nakalipas. "Sa kabuuan ay may mga anim na raang fresco at labinlimang daang mga ukit sa Lascaux labyrinth. Mayroong malakas na umuungol na itim na lalaki, isang tumatalon na baka, at isang prusisyon ng mga kabayo na gumagalaw sa kabilang direksyon. Sa pasukan sa isa pang mahabang daanan na kilala bilang Nave, isang frieze ng eleganteng usa ang ipininta sa itaas ng Preamble: Ang pilosopo, Susanne K. Langer, sa kanyang artikulo, The Cultural Importance of the Arts. Itinatampok ni Langer ang aspeto ng sining bilang isang banayad at walang malay na impluwensya at puwersa sa lipunan at kultura. "Ang bawat kultura ay bubuo ng ilang uri ng sining na kasingtiyak ng pagbuo ng wika. Ang ilang mga primitive na kultura ay walang tunay na mitolohiya o relihiyon, ngunit lahat ay may ilang sining-sayaw, kanta, disenyo (kung minsan ay sa mga kasangkapan lamang o sa katawan ng tao). Sayaw, higit sa lahat, tila ito ang pinakalumang sining na may paliwanag.....
Growth arrest specific 6 - Feasible marker for septic patients and potential architect in the improvement of sepsis-induced organ damage in mice
Creators: name: SALMI, Livia
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2021

description: Sepsis is a widespread life-threatening disease, with a high mortality rate due to inflammation-induced multiorgan failure (MOF). Thus, new effective modulators of the immune response are urgently needed to ameliorate the outcome of septic patients. As growth arrest-specific gene 6 (Gas6)/Tyro3, Axl, MerTK (TAM) receptors signaling has shown immunomodulatory activity in sepsis, here we sought to determine whether Gas6 protein injection could mitigate MOF in a cecal slurry mouse model of sepsis. Mice, divided into different groups according to treatment-i.e., septic (B), ampicillin (BA), Gas6 alone (BG), and ampicillin plus Gas6 (BAG)-were assessed for vitality, histopathology and cytokine expression profile as well as inducible nitric oxide synthase (iNOS), ALT and LDH levels. BAG-treated mice displayed milder kidney and lung damage and reduced levels of cytokine expression and iNOS in the lungs compared to BA-treated mice. Notably, BAG-treated mice showed lower LDH levels compared to controls. Lastly, BAG-treated cells of dendritic, endothelial or monocytic origin displayed reduced ROS formation and increased cell viability, with a marked upregulation of mitochondrial activity. Altogether, our findings indicate that combined treatment with Gas6 and antibiotics ameliorates sepsis-induced organ damage and reduces systemic LDH levels in mice, suggesting that Gas6 intravenous injection may be a viable therapeutic option in sepsis.
sj-pdf-1-amd-10.1177_11795441211028751 – Supplemental material for Cardiovascular Disease in Rheumatoid Arthritis: Risk Factors, Autoantibodies, and the Effect of Antirheumatic Therapies
Creators: name: Fazeli, Mir Sohail
name: Khaychuk, Vadim
name: Wittstock, Keith
name: Breznen, Boris
name: Crocket, Grace
name: Pourrahmat, Mir-Masoud
name: Ferri, Leticia
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, sj-pdf-1-amd-10.1177_11795441211028751 for Cardiovascular Disease in Rheumatoid Arthritis: Risk Factors, Autoantibodies, and the Effect of Antirheumatic Therapies by Mir Sohail Fazeli, Vadim Khaychuk, Keith Wittstock, Boris Breznen, Grace Crocket, Mir-Masoud Pourrahmat and Leticia Ferri in Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
Additional file 15 of Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling
Creators: name: Lyu, Taibiao
name: Jiang, Hui
name: Zeng, Liuting
name: Liu, Suying
name: He, Chengmei
name: Luo, Chaowen
name: Qiao, Lin
name: Zhao, Yan
name: Chen, Hua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 15: Supplementary Figure S9. IGU suppresses B cell differentiation.
sj-pdf-1-hsx-10.1177_10887679211018492 – Supplemental material for The Crisis of Social Institutions and Police Homicides: The Adverse Effects of Low Institutional Control
Creators: name: Wetherell, Kamali’ilani T. E.
name: Miethe, Terance D.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, sj-pdf-1-hsx-10.1177_10887679211018492 for The Crisis of Social Institutions and Police Homicides: The Adverse Effects of Low Institutional Control by Kamali’ilani T. E. Wetherell and Terance D. Miethe in Homicide Studies
Investigating Health Decision-Making in Adults Diagnosed with Autism Spectrum Disorder.docx
Creators: name: Porter, Kimberly Ann Paulin
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 420599
subject: Nursing not elsewhere classified

description: This study investigates healthcare decision-making dynamics among adults diagnosed with autism spectrum disorder (ASD) without intellectual disability (ID), focusing on the influence of the egocentric norm concept and comparing it to neurotypical (NT) individuals. Employing a quasi-experimental design and meticulously developed vignettes, the research gathers quantitative and qualitative data from Prolific survey responses, exploring nuances in decision processes. The findings reveal substantial disparities in response patterns between individuals with ASD without ID and NT counterparts, emphasizing the significance of the egocentric norm. Factor analysis and structural equation modeling support the validity of the questions and highlight egocentric norms’ impactful role in health-related decisions.Qualitatively, themes within both groups illuminate unique decision-making processes, including enduring support from significant others, autonomy trends, and reliance on digital resources. The study contributes nuanced insights for healthcare practitioners, policymakers, and educators, emphasizing the need for tailored interventions that resonate with the distinctive decision-making dynamics of individuals with ASD without ID. While acknowledging limitations related to sample characteristics and reliance on self-reported data, the study provides an in-depth understanding of the interplay between the egocentric norm, Reasoned Action Approach (RAA) concepts, and other influential factors in healthcare decision-making.
Development of sensitive methods for detection of porcine endogenous retrovirus-C (PERV-C) in the genome of pigs
Creators: name: Kaulitz, Danny
name: Mihica, Debora
name: Dorna, Jens
name: Costa, Michael Rodrigues
name: Petersen, Björn
name: Niemann, Heiner
name: Tönjes, Ralf R.
name: Denner, Joachim
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2011
Subjects: subject: Xenotransplantation
subject: Porcine endogenous retroviruses (PERV)
subject: Nested PCR
subject: Real-time PCR
subject: 610 Medizin

description: Porcine endogenous retroviruses (PERV) represent a risk for xenotransplantation using pig cells, tissues or organs. PERV-A and PERV-B are present in the genome of all pigs and both infect human cells in vitro. PERV-C infects only pig cells and it is integrated in the genome of most, but not all pigs. Recombinants between PERV-A and PERV-C were described that infect human cells and replicate at high titres. To avoid such recombinations, PERV-C positive animals should not be used for breeding animals suited for xenotransplantation. In order to detect PERV-C positive pigs, different methods were developed such as specific PCRs using different primers, a highly sensitive nested PCR and a real-time PCR allowing measurement of proviral copy numbers. The real-time PCR was found to be useful to discriminate between contamination and actual provirus copies. The PCRs were optimized and their sensitivity was determined. Screening can be started with PCR1, if the result is negative, PCR2 to PCR5 or the nested PCR should be used, if the result is positive, the real-time PCR should be used to exclude contaminations. All methods were used to evaluate the prevalence of PERV-C and to identify PERV-C free animals. Due to the risk of contamination with cells from other animals testing should be performed with blood cells, not with ear biopsies.
Albania's Parliamentary Administration
Creators: name: Krasniqi, Afrim
Publisher: name: Routledge
Year: 2023

description: Albania current parliamentary system has only 30 years of age. Since 1990, Albania is a parliamentary republic, with a unicameral parliament composed of 140 MPs. The Assembly is recognized as Albania's main representative political institution, but the Constitution does not provide any definition of the role and function of the Assembly and of its position in relation to other constitutional bodies, describing it only as the highest body that exercises legislative power. In 2020, Albania marked the 100th anniversary of the first parliament, and the scientific papers of the conference, with research authors and academics, constitute some of the few reference sources on Albanian parliamentarism. Generally, Albanian state institutions, including the Assembly, prefer to resort to the financial compensation of the unjustly fired staffers through funding from the state budget, rather than to proceed with the reinstatement of the dismissed officials for political reasons.
Magnetic fields from small-scale primordial perturbations
Creators: name: Lee, Nanoom
name: Ali-Haimoud, Yacine
Publisher: name: arXiv
Year: 2024
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Weak magnetic fields must have existed in the early Universe, as they were sourced by the cross product of electron density and temperature gradients through the Biermann-battery mechanism. In this paper we calculate the magnetic fields generated at cosmic dawn by a variety of small-scale primordial perturbations, carefully computing the evolution of electron density and temperature fluctuations, and consistently accounting for relative velocities between baryons and dark matter. We first compute the magnetic field resulting from standard, nearly scale-invariant primordial adiabatic perturbations, making significant improvements to previous calculations. This "standard" primordial field has a root mean square (rms) of $\sim10^{-15}$ nG at $20\lesssim z \lesssim 100$, with fluctuations on $\sim$ kpc comoving scales, and could serve as the seed of present-day magnetic fields observed in galaxies and galaxy clusters. In addition, we consider early-Universe magnetic fields as a possible probe of non-standard initial conditions of the Universe on small scales $k \sim 1-10^3$ Mpc$^{-1}$. To this end, we compute the maximally-allowed magnetic fields within current upper limits on small-scale adiabatic and isocurvature perturbations. Under the current Cosmic Microwave Background spectral-distortion constraints magnetic fields could be produced with a rms of $\sim 5\times 10^{-11}$ nG at $z = 20$. Uncorrelated small-scale isocurvature perturbations within current Big-Bang Nucleosynthesis bounds could potentially enhance the magnetic field to $\sim 10^{-14}-10^{-10}$ nG at $z = 20$, depending on the specific isocurvature mode considered. While these very weak fields remain well below current observational capabilities, our work points out that magnetic fields could potentially provide an interesting window into the poorly constrained small-scale initial conditions of the Universe.
description: 12 pages, 6 figures