cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phase 2 Study of the Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Men Who Have Sex With Men (HPTN 069/ACTG A5305)
Creators: name: McGowan, Ian
name: Frank, Ian
name: Eshleman, Susan H
name: Ho, Ken
name: Salata, Robert A
name: Santana, Jorge
name: Hendrix, Craig W
name: Rivet Amico,
name: Liu, Albert
name: Chen, Ying Q
name: Chege, Wairimu
name: Rinehart, Alex R
name: Richardson, Paul
name: Klingman, Karin L
name: Andrade, Adriana
name: Landovitz, Raphael J
name: Marzinke, Mark A
name: Wilkin, Timothy J
name: Cottle, Leslie M
name: Mayer, Kenneth H
name: Stekler, Joanne D
name: Marcus, Cheryl
name: Young, Alicia M
name: Farley, Jason E
name: Magnus, Manya
name: Gulick, Roy M
name: Andrew, Philip
name: Rooney, James F
name: McCauley, Marybeth
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Maraviroc (MVC) is a candidate for human immunodeficiency virus (HIV) pre-exposure prophylaxis.
Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents
Creators: name: Margolis, David M.
name: Archin, Nancie M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Quiescent proviral genomes that persist during human immunodeficiency virus type 1 (HIV-1) infection despite effective antiretroviral therapy (ART) can fuel rebound viremia after ART interruption and is a central obstacle to the cure of HIV infection. The induction of quiescent provirus is the goal of a new class of potential therapeutics, latency reversing agents (LRAs). The discovery, development, and testing of HIV LRAs is a key part of current efforts to develop latency reversal and viral clearance strategies to eradicate established HIV infection. The development of LRAs is burdened by many uncertainties that make drug discovery difficult. The biology of HIV latency is complex and incompletely understood. Potential targets for LRAs are host factors, and the potential toxicities of host-directed therapies in individuals that are otherwise clinically stable may be unacceptable. Assays to measure latency reversal and assess the effectiveness of potential therapeutics are complex and incompletely validated. Despite these obstacles, novel LRAs are under development and beginning to enter combination testing with viral clearance strategies. It is hoped that the steady advances in the development of LRAs now being paired with emerging immunotherapeutics to clear persistently infected cells will soon allow measurable clinical advances toward an HIV cure.
Superconductive and insulating inclusions for linear and non-linear conductivity equations
Creators: name: Brander, Tommi
name: Ilmavirta, Joonas
name: Kar, Manas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35R30, 35J92 (Primary), 35H99 (Secondary)

description: We detect an inclusion with infinite conductivity from boundary measurements represented by the Dirichlet-to-Neumann map for the conductivity equation. We use both the enclosure method and the probe method. We use the enclosure method to prove partial results when the underlying equation is the quasilinear $p$-Laplace equation. Further, we rigorously treat the forward problem for the partial differential equation $\operatorname{div}(σ\lvert\nabla u\rvert^{p-2}\nabla u)=0$ where the measurable conductivity $σ\colonΩ\to[0,\infty]$ is zero or infinity in large sets and $1
description: 39 pages
Orbital evolution of planetesimals in gaseous disks
Creators: name: Kobayashi, Hiroshi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Planets are formed from collisional growth of small bodies in a protoplanetary disk. Bodies much larger than approximately $1$\,m are mainly controlled by the gravity of the host star and experience weak gas drag; their orbits are mainly expressed by orbital elements: semimajor axes $a$, eccentricities $e$, and inclinations $i$, which are modulated by gas drag. In a previous study, $\dot a$, $\dot e$, and $\dot i$ were analytically derived for $e \ll 1$ and $i \ll H/a$, where $H$ is the scale height of the disk. Their formulae are valid in the early stage of planet formation. However, once massive planets are formed, $e$ and $i$ increase greatly. Indeed, some small bodies in the solar system have very large $e$ and $i$. Therefore, in this paper, I analytically derive formulae for $\dot a$, $\dot e$, and $\dot i$ for $1-e^2 \ll 1$ and $i \ll H/a$ and for $i \gg H/a$. The formulae combined from these limited equations will represent the results of orbital integration unless $e \geq 1$ or $i > π- H/a$. Since the derived formulae are applicable for bodies not only in a protoplanetary disk but also in a circumplanetary disk, I discuss the possibility of the capture of satellites in a circumplanetary disk using the formulae.
description: accepted for publication in Earth, Planets and Space, 11 pages, 4 figures
title: Addition of diffusion-weighted imaging for the clinical MR assessment of acute pyelonephritis (APN): a prospective multicentric study
Creators: name: Albarello, Fabrizio
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Kidney
subject: Emergency
subject: Radioprotection / Radiation dose
subject: MR-Diffusion/Perfusion
subject: Ultrasound-Colour Doppler
subject: Imaging sequences
subject: Comparative studies
subject: Inflammation
subject: Abscess

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Acute Pyelonephritis (APN) is a very common diagnosis in the emergency department, usually clinically assessed and managed. Nevertheless, a color-Doppler ultrasound (CDUS) is often requested to exclude hydronephrosis or renal abscess. Several...
Race/Ethnicity and the Pharmacogenetics of Reported Suicidality With Efavirenz Among Clinical Trials Participants
Creators: name: Hudgens, Michael G.
name: Tierney, Camlin
name: Ventura, Diana
name: Sax, Paul E.
name: Haas, David W.
name: Ma, Qing
name: Haubrich, Richard
name: Robertson, Kevin R.
name: Hellwege, Jacklyn N.
name: Gulick, Roy M.
name: Daar, Eric S.
name: Velez Edwards, Digna R.
name: Campbell, Thomas B.
name: Mollan, Katie R.
name: Eron, Joseph J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Abstract Background: We examined associations between suicidality and genotypes that predict plasma efavirenz exposure among AIDS Clinical Trials Group study participants in the United States. Methods: Four clinical trials randomly assigned treatment-naive participants to efavirenz-containing regimens; suicidality was defined as reported suicidal ideation or attempted or completed suicide. Genotypes that predict plasma efavirenz exposure were defined by CYP2B6 and CYP2A6 polymorphisms. Associations were evaluated with weighted Cox proportional hazards models stratified by race/ethnicity. Additional analyses adjusted for genetic ancestry and selected covariates. Results: Among 1833 participants, suicidality was documented in 41 in exposed analyses, and 34 in on-treatment analyses. In unadjusted analyses based on 12 genotype levels, suicidality increased per level in exposed (hazard ratio, 1.11; 95% confidence interval, .96–1.27) and on-treatment 1.16; 1.01–1.34) analyses. In the on-treatment analysis, the association was strongest among white but nearly null among black participants. Considering 3 metabolizer levels (extensive, intermediate and slow), slow metabolizers were at increased risk. Results were similar after baseline covariate-adjustment for genetic ancestry, sex, age, weight, injection drug use history, and psychiatric history or recent psychoactive medication. Conclusions: Genotypes that predict higher plasma efavirenz exposure were associated with increased risk of suicidality. Strength of association varied by race/ethnicity.
Effects of local and global network connectivity on synergistic epidemics
Creators: name: Broder-Rodgers, David
name: Pérez-Reche, Francisco J.
name: Taraskin, Sergei N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The effects of local and global connectivity on the spread of synergistic susceptible-infected-removed epidemics were studied in lattice models with infinite- and finite-range rewiring (small-world and small-world-like models). Several effects were found numerically and supported analytically within a simple model: (i) rewiring enhanced resilience to epidemics with strong constructive synergy on networks with high local connectivity; (ii) rewiring enhanced spread of epidemics with destructive or weak constructive synergy on networks with arbitrary local connectivity; (iii) rewiring enhanced spread of epidemics, independent of synergy, in networks with low local connectivity.
Bernardia leptostachys Chodat & Hassl., Bull. Herb. Boissier
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Bernardia
Bernardia leptostachys

description: Bernardia leptostachys Chodat & Hassl., Bull. Herb. Boissier, sér. 2(5): 506. 1905.
Subshrub.
 Vouchers: Canindeyú: Hassler 5081, type (G).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study
Creators: name: Vendrov, Kimberly C.
name: Stouffer, George A.
name: Bai, Xue
name: Lee, Craig R.
name: Oni-Orisan, Akinyemi
name: Wells, Michael A.
name: Taylor, Joan M.
name: Christensen, Erin S.
name: Edin, Matthew L.
name: Zeldin, Darryl C.
name: Lih, Fred B.
name: Lee, John Andrew
name: Tomer, Kenneth B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) exhibit potent cardiovascular protective effects in preclinical models, and promoting the effects of EETs has emerged as a potential therapeutic strategy for coronary artery disease (CAD). The relationship between circulating EET levels and CAD extent in humans, however, remains unknown. A panel of free (unesterified) plasma eicosanoid metabolites was quantified in 162 patients referred for coronary angiography, and associations with extent of CAD [no apparent CAD (N = 39), nonobstructive CAD (N = 51), and obstructive CAD (N = 72)] were evaluated. A significant relationship between free EET levels and CAD extent was observed (P = 0.003) such that the presence of obstructive CAD was associated with lower circulating EET levels. This relationship was confirmed in multiple regression analysis where CAD extent was inversely and significantly associated with EET levels (P = 0.013), and with a biomarker of EET biosynthesis (P < 0.001), independent of clinical and demographic factors. Furthermore, quantitative enrichment analysis revealed that these associations were the most pronounced compared with other eicosanoid metabolism pathways. Collectively, these findings suggest that the presence of obstructive CAD is associated with lower EET metabolite levels secondary to suppressed EET biosynthesis. Novel strategies that promote the effects of EETs may have therapeutic promise for patients with obstructive CAD.
Parameterized post-Newtonian limit of Horndeski's gravity theory
Creators: name: Hohmann, Manuel
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a recent result on the parameterized post-Newtonian (PPN) limit of Horndeski's gravity theory and its consistency with solar system observations.
description: 2 pages, no figures; to appear in the conference proceedings of the XIIth International Conference on Gravitation, Astrophysics and Cosmology, World Scientific Publishing Company
A dual method of constructing hereditarily indecomposable Banach spaces
Creators: name: Argyros, Spiros A.
name: Motakis, Pavlos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 46B03, 46B06, 46B25, 46B45, 47A15

description: A new method of defining hereditarily indecomposable Banach spaces is presented. This method provides a unified approach for constructing reflexive HI spaces and also HI spaces with no reflexive subspace. All the spaces presented here satisfy the property that the composition of any two strictly singular operators is a compact one. This yields the first known example of a Banach space with no reflexive subspace such that every operator has a non-trivial closed invariant subspace.
description: 41 pages
Bernardia simplex Chodat & Hassl., Bull. Herb. Boissier
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Bernardia
Bernardia simplex

description: Bernardia simplex Chodat & Hassl., Bull. Herb. Boissier, sér. 2(5): 505. 1905.
Herb or subshrub.
 Vouchers: Amambay: Krapovickas et al. 46057 (K). Canindeyú: Hassler 4569, type of B. simplex (BM, NY).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
On the Analysis of Bell's 1964 Paper by Wiseman, Cavalcanti, and Rieffel
Creators: name: Gillis, Edward J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: In a recent series of papers Wiseman, Cavalcanti, and Rieffel have outlined and contrasted two different views about what we now call Bell's theorem. They also assert that Bell presented these two different versions at different times. This view is clearly at odds with the detailed explanation that Bell himself gave in his later writings. A careful examination of the historic 1964 paper in context shows clearly that Bell's own later interpretation is the correct one.
description: 16 pages. Revised. Published in International Journal of Quantum Foundations
Les projets de sciences participatives à l’École : pour quelle authenticité de l’enseignement-apprentissage en sciences ? Cas du projet Oak bodyguards en France
Creators: name: PERRON (Switzerland), SÉVERINE
name: MARZIN-JANVIER (France), PATRICIA
Publisher: name: Review of Science, Mathematics and ICT Education
Year: 2022
Subjects: Science education, participatory science, authenticity of learning, teaching practices, school-scientist partnerships

description: In the context of this article, we wonder about the possibilities that a teaching sequence, based on citizen science and implemented in class by a teacher and his students, can keep a form of authenticity, even though the students have never met or communicated with the scientists carrying out the project. Our study is based on the constructs of authenticity and teaching practice. Data is collected from video recordings of class sessions. The results show that teachers, because of their didactic and pedagogical choices, can recreate a disciplinary authenticity reinforced by an epistemological authenticity.
description: Review of Science, Mathematics and ICT Education, Forthcoming papers
Quantitative profiling of the endonuclear glycerophospholipidome of murine embryonic fibroblasts
Creators: name: Faenza, Irene
name: Bankaitis, Vytas A.
name: Ivanova, Pavlina T.
name: Cocco, Lucio
name: Alb, James G.
name: Brown, H. Alex
name: Tribble, Emily K.
name: Grabon, Aby
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: A reliable method for purifying envelope-stripped nuclei from immortalized murine embryonic fibroblasts (iMEFs) was established. Quantitative profiling of the glycerophospholipids (GPLs) in envelope-free iMEF nuclei yields several conclusions. First, we find the endonuclear glycerophospholipidome differs from that of bulk membranes, and phosphatidylcholine (PtdCho) and phosphatidylethanolamine species are the most abundant endonuclear GPLs by mass. By contrast, phosphatidylinositol (PtdIns) represents a minor species. We also find only a slight enrichment of saturated versus unsaturated GPL species in iMEF endonuclear fractions. Moreover, much lower values for GPL mass were measured in the iMEF nuclear matrix than those reported for envelope-stripped IMF-32 nuclei. The collective results indicate that the nuclear matrix in these cells is a GPL-poor environment where GPL occupies only approximately 0.1% of the total nuclear matrix volume. This value suggests GPL accommodation in this compartment can be satisfied by binding to resident proteins. Finally, we find no significant role for the PtdIns/PtdCho-transfer protein, PITPα, in shuttling PtdIns into the iMEF nuclear matrix.
Caperonia altissima Eskuche, Candollea
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Caperonia
Caperonia altissima

description: Caperonia altissima Eskuche, Candollea 57(2): 288. 2002.
Herb.
 Vouchers: San Pedro: Eskuche & Ahumada 6139, type (G).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits
Creators: name: Allayee, Hooman
name: Lusis, Aldons J.
name: Eskin, Eleazar
name: Norheim, Frode
name: Davis, Richard C.
name: Mehrabian, Margarete
name: Seldin, Marcus M.
name: Vallim, Thomas
name: Pan, Calvin
name: Rau, Christoph D.
name: Civelek, Mete
name: Wang, Yibin
name: Bennett, Brian J.
name: Hui, Simon
name: Parks, Brian
name: Farber, Charles R.
name: Wang, Jessica
name: Smith, Desmond J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The Hybrid Mouse Diversity Panel (HMDP) is a collection of approximately 100 well-characterized inbred strains of mice that can be used to analyze the genetic and environmental factors underlying complex traits. While not nearly as powerful for mapping genetic loci contributing to the traits as human genome-wide association studies, it has some important advantages. First, environmental factors can be controlled. Second, relevant tissues are accessible for global molecular phenotyping. Finally, because inbred strains are renewable, results from separate studies can be integrated. Thus far, the HMDP has been studied for traits relevant to obesity, diabetes, atherosclerosis, osteoporosis, heart failure, immune regulation, fatty liver disease, and host-gut microbiota interactions. High-throughput technologies have been used to examine the genomes, epigenomes, transcriptomes, proteomes, metabolomes, and microbiomes of the mice under various environmental conditions. All of the published data are available and can be readily used to formulate hypotheses about genes, pathways and interactions.
Caperonia capiibarensis Eskuche, Candollea
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Caperonia
Caperonia capiibarensis

description: Caperonia capiibarensis Eskuche, Candollea 57(2): 290. 2002.
Herb.
 Vouchers: Guairá: Schinini 5877 (CTES); Schinini 5892 (CTES). San Pedro: Eskuche & Ahumada 6404, type (G); Krapovickas et al. 14304 (CTES).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Caperonia paraguayensis Pax & K. Hoffm., Pflanzenr., IV
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Caperonia
Caperonia paraguayensis

description: Caperonia paraguayensis Pax & K.Hoffm., Pflanzenr., IV, 147, VI: 35. 1912.
Herb.
 Vouchers: San Pedro: Hassler 8102, type (BM, F, GH, K, P, S); Zardini & Guerrero 46619 (AS, MO).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Fermionic phase transition induced by the effective impurity in holography
Creators: name: Fang, Li-Qing
name: Kuang, Xiao-Mei
name: Wang, Bin
name: Wu, Jian-Pin
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the holographic fermionic phase transition induced by the effective impurity in holography, which is introduced by massless scalar fields in Einstein-Maxwell-massless scalar gravity. We obtain a phase diagram in $(α, T)$ plane separating the Fermi liquid phase and the non-Fermi liquid phase.
description: 17 pages, 9 figures
Kosterlitz-Thouless transitions and phase diagrams of the interacting monomer-dimer model on a checkerboard lattice
Creators: name: Li, Sazi
name: Li, Wei
name: Chen, Ziyu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Using the tensor network approach, we investigate the monomer-dimer models on a checkerboard lattice, in which there are interactions (with strength $ν$) between the parallel dimers on half of the plaquettes. For the fully packed interacting dimer model, we observe a Kosterlitz-Thouless (KT) transition between the lowtemperature symmetry breaking and the high-temperature critical phases; for the doped monomer-dimer casewith finite chemical potential $μ$, we also find an order-disorder phase transition which is of second order instead. We use the boundary matrix product state approach to detect the KT and second-order phase transitions and obtain the phase diagrams $ν-T$ and $μ-T$ . Moreover, for the noninteracting monomer-dimer model (setting $μ= ν= 0$), we get an extraordinarily accurate determination of the free energy per site (negative of the monomer-dimer constant $h_2$) as $f=-0.662\, 798\, 972\, 833\, 746$ with the dimer density $n=0.638\, 123\, 109\, 228\, 547$, both of 15 correct digits.
description: 8 pages, 15 figures
Baryogenesis in a CP invariant theory
Creators: name: Hook, Anson
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider baryogenesis in a model which has a CP invariant Lagrangian, CP invariant initial conditions and does not spontaneously break CP at any of the minima. We utilize the fact that tunneling processes between CP invariant minima can break CP to implement baryogenesis. CP invariance requires the presence of two tunneling processes with opposite CP breaking phases and equal probability of occurring. In order for the entire visible universe to see the same CP violating phase, we consider a model where the field doing the tunneling is the inflaton.
description: 12 pages
Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids
Creators: name: Chen, Shufen
name: Lih, Fred B.
name: Yechoor, Alekhya
name: Coleman, Rosalind A.
name: Klett, Eric L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Because the signaling eicosanoids, epoxyeicosatrienoic acids (EETs) and HETEs, are esterified to membrane phospholipids, we asked which long-chain acyl-CoA synthetase (ACSL) isoforms would activate these molecules and whether the apparent FA substrate preferences of each ACSL isoform might differ depending on whether it was assayed in mammalian cell membranes or as a purified bacterial recombinant protein. We found that all five ACSL isoforms were able to use EETs and HETEs as substrates and showed by LC-MS/MS that ACSLs produce EET-CoAs. We found differences in substrate preference between ACS assays performed in COS7 cell membranes and recombinant purified proteins. Similarly, preferences and Michaelis-Menten kinetics for long-chain FAs were distinctive. Substrate preferences identified for the purified ACSLs did not correspond to those observed in ACSL-deficient mouse models. Taken together, these data support the concept that each ACSL isoform exhibits a distinct substrate preference, but apparent substrate specificities depend upon multiple factors including membrane character, coactivators, inhibitors, protein interactions, and posttranslational modification.
Cnidoscolus pteroneurus Fern. Casas, Fontqueria
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Cnidoscolus
Cnidoscolus pteroneurus

description: Cnidoscolus pteroneurus Fern.Casas, Fontqueria 55: 187. 2004.
Herb or subshrub.
 Vouchers: Alto Paraguay: Caballero Marmori 4114, type (MBM).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases
Creators: name: Lusis, Aldons J.
name: Collins, Francis S.
name: Mohlke, Karen L.
name: Stančáková, Alena
name: Pajukanta, Päivi
name: Laakso, Markku
name: Kuulasmaa, Teemu
name: Kuusisto, Johanna
name: Boehnke, Michael
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The Metabolic Syndrome in Men (METSIM) study is a population-based study including 10,197 Finnish men examined in 2005–2010. The aim of the study is to investigate nongenetic and genetic factors associated with the risk of T2D and CVD, and with cardiovascular risk factors. The protocol includes a detailed phenotyping of the participants, an oral glucose tolerance test, fasting laboratory measurements including proton NMR measurements, mass spectometry metabolomics, adipose tissue biopsies from 1,400 participants, and a stool sample. In our ongoing follow-up study, we have, to date, reexamined 6,496 participants. Extensive genotyping and exome sequencing have been performed for essentially all METSIM participants, and >2,000 METSIM participants have been whole-genome sequenced. We have identified several nongenetic markers associated with the development of diabetes and cardiovascular events, and participated in several genetic association studies to identify gene variants associated with diabetes, hyperglycemia, and cardiovascular risk factors. The generation of a phenotype and genotype resource in the METSIM study allows us to proceed toward a “systems genetics” approach, which includes statistical methods to quantitate and integrate intermediate phenotypes, such as transcript, protein, or metabolite levels, to provide a global view of the molecular architecture of complex traits.
Croton berberifolius Croizat, Darwiniana
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Croton
Croton berberifolius

description: Croton berberifolius Croizat, Darwiniana 6: 459. 1944.
Subshrub.
 Vouchers: Amambay: Hassler 10059 (BM, K); Hassler 11211, type of Croton berberifolius (BM, G, GH, K). Paraguarí: Zardini & Guerrero 31055 (MO, PY).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Unitarity and the three flavour neutrino mixing matrix
Creators: name: Parke, Stephen
name: Ross-Lonergan, Mark
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Unitarity is a fundamental property of any theory required to ensure we work in a theoretically consistent framework. In comparison with the quark sector, experimental tests of unitarity for the 3x3 neutrino mixing matrix are considerably weaker. It must be remembered that the vast majority of our information on the neutrino mixing angles originates from $\overlineν_e$ and $ν_μ$ disappearance experiments, with the assumption of unitarity being invoked to constrain the remaining elements. New physics can invalidate this assumption for the 3x3 subset and thus modify our precision measurements. We perform a reanalysis to see how global knowledge is altered when one refits oscillation results without assuming unitarity, and present $3 σ$ ranges for allowed $U_\text{PMNS}$ elements consistent with all observed phenomena. We calculate the bounds on the closure of the six neutrino unitarity triangles, with the closure of the $ν_e ν_μ$ triangle being constrained to be $\leq$ 0.03, while the remaining triangles are significantly less constrained to be $\leq$ 0.1 - 0.2. Similarly for the row and column normalization, we find their deviation from unity is constrained to be $\leq$ 0.2 - 0.4, for four out of six such normalisations, while for the $ν_μ$ and $ν_e$ row normalisation the deviations are constrained to be $\leq$ 0.07, all at the $3σ$ CL. We emphasise that there is significant room for new low energy physics, especially in the $ν_τ$ sector which very few current experiments constrain directly.
description: 8 pages, 3 figures and 1 table
Supplementary material of the impact of Ibero-American science on global bioethical thinking
Creators: name: Valderrama-Zurián, JC
name: Aleixandre-Benavent, R
name: Aznar, J
Publisher: name: Zenodo
Year: 2020
Subjects: bioethics
bioethics quality
Ibero-American countries
bibliometrics
languages
research

description: Supplementary material of the paper "The impact of Ibero-American science on global bioethical thinking". Search equation in Web of Science Core Collection, peer-reviewed journals selected, tables and figures.
Do Sleep Disturbances Predict or Moderate the Response to Psychotherapy in Bipolar Disorder?
Creators: name: Frank, Ellen
name: Peters, Amy T.
name: Salcedo, Stephanie
name: Da Silva Magalhães, Pedro Vieira
name: Otto, Michael W.
name: Sylvia, Louisa G.
name: Deckersbach, Thilo
name: Berk, Michael
name: Nierenberg, Andrew A.
name: Miklowitz, David J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: This study examined whether sleep disturbance predicted or moderated responses to psychotherapy in participants who participated in STEP-BD, a national, multi-site study that examined the effectiveness of different treatment combinations for bipolar disorder. Participants received either a brief psychosocial intervention called collaborative care (CC; n=130), or intensive psychotherapy (IP; n=163), with study-based pharmacotherapy. Participants (N=243) were defined as current (past week) short sleepers (<6 hours/night), normal sleepers (6.5-8.5 hours/night), and long sleepers (≥9 hours/night), according to reported average nightly sleep duration the week before randomization. Sleep disturbances did not predict the likelihood of recovery nor time until recovery from a depressive episode. There was no difference in recovery rates between IP versus CC for normal sleepers, and medium effect sizes were observed for differences in short and long sleepers. In this study, sleep did not play a major role in predicting or moderating response to psychotherapy in bipolar disorder.
Brillouin amplification supports $1\times10^{-20}$ accuracy in optical frequency transfer over 1400~km of underground fibre
Creators: name: Raupach, Sebastian M. F.
name: Koczwara, Andreas
name: Grosche, Gesine
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We investigate optical frequency transfer over a 1400~km loop of underground fibre connecting Braunschweig and Strasbourg. Largely autonomous fibre Brillouin amplifiers (FBA) are the only means of intermediate amplification, allowing phase-continuous measurements over periods up to several days. Over a measurement period of about three weeks we find a weighted mean of the transferred frequency's fractional offset of $(1.1\pm0.4)\times10^{-20}$. In the best case we find an instability of $6.9\times10^{-21}$ and a fractional frequency offset of $4.4\times10^{-21}$ at an averaging time of around 30~000~s. These results represent an upper limit for the achievable uncertainty over 1400 km when using a chain of remote Brillouin amplifiers, and allow us to investigate systematic effects at the $10^{-20}$-level.
Croton integrilobus Croizat, Darwiniana
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Croton
Croton integrilobus

description: Croton integrilobus Croizat, Darwiniana 6: 460. 1944.
Subshrub.
 Vouchers: Alto Paraguay: Rojas 3708 (A, GH).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Supplementary material of the study: "Global Scientific Production on behavioural addictions: An analysis of the literature from 1995 to 2019"
Creators: name: Sixto-Costoya, Andrea
name: Castelló-Cogollos, Lourdes
name: Aleixandre-Benavent, Rafael
name: Valderrama-Zurián, Juan Carlos
Publisher: name: Zenodo
Year: 2021
Subjects: behavioural addiction, gambling, gaming, sex addiction, food addiction, sport addiction, shopping addiction, bibliometric study, geographical differences

description: These archives are related to the study about the global scientific publication on behavioural addictions from 1994 to 2019. The behavioural addictions that we considered in our study were: gambling, gaming, ITC related disorders, sex addiction, food addiction, sport addiction, shopping addiction. Here we define the content of each file: - Supplementary material 1: Search equation designed and used in Web of Science to find our results. - Supplementary material 2: Examples of reasons for the exclusion of records that were initially recovered in WoS with the search equation designed. - Supplementary material 3: List of countries that have at least one article about behavioural addiction, with their population, continent and region. The countries and populations were obtained from the World Data Bank. - Supplementary material 4: Regional and global publications on behavioral addictions in 1995–2019
Fas Regulates Macrophage Polarization and Fibrogenic Phenotype in a Model of Chronic Ethanol-Induced Hepatocellular Injury
Creators: name: Wheeler, Michael D.
name: Hines, Ian N.
name: Moore, Sherri
name: Isayama, Fuyumi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The role of Fas-mediated apoptosis and its effect on proinflammatory cytokine production in early alcoholic liver disease has not been addressed. Wild-type mice (C57Bl/6) or mice with a functional mutation in the Fas ligand (B6.
Asymptotics of correlation functions of the Heisenberg-Ising chain in the easy-axis regime
Creators: name: Dugave, Maxime
name: Göhmann, Frank
name: Kozlowski, Karol K.
name: Suzuki, Junji
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Gases (cond-mat.quant-gas)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We analyze the long-time large-distance asymptotics of the longitudinal correlation functions of the Heisenberg-Ising chain in the easy-axis regime. We show that in this regime the leading asymptotics of the dynamical two-point functions is entirely determined by the two-spinon contribution to their form factor expansion. Its explicit form is obtained from a saddle-point analysis of the corresponding double integral. It describes the propagation of a wave front with velocity $v_{c_1}$ which is found to be the maximal possible group velocity. Like in wave propagation in dispersive media the wave front is preceded by a precursor running ahead with velocity $v_{c_2}$. As a special case we obtain the explicit form of the asymptotics of the auto-correlation function.
description: v2: 13 pages LaTeX, three more figures added, comments added in introduction and discussion
Additional file 1 of Age and product dependent vaccine effectiveness against SARS-CoV-2 infection and hospitalisation among adults in Norway: a national cohort study, July–November 2021
Creators: name: Starrfelt, Jostein
name: Danielsen, Anders Skyrud
name: Buanes, Eirik Alnes
name: Juvet, Lene Kristine
name: Lyngstad, Trude Marie
name: Rø, Gunnar Øyvind Isaksson
name: Veneti, Lamprini
name: Watle, Sara Viksmoen
name: Meijerink, Hinta
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 1. Details on the data sources and variables as well as the epidemiological situation in Norway during the study period. In addition, this additional file contains all numbers underlying the visual representation in this manuscript and additional sensitivity analyses performed, such as unadjusted estimates, and estimated on sub-cohorts. Additional File 1: Tables S1-S9 and Figs. S1-S4. Table S1. Description of data sources and variables used in this study. Table S2. Vaccine effectiveness against SARS-CoV-2 infection for all adults (18+) in Norway. Table S3. Vaccine effectiveness against hospitalisation for all adults (18+) in Norway. Table S4. Vaccine effectiveness against ICU admission for all adults (18+) in Norway. Table S5. Vaccine effectiveness against mortality for all adults (18+) in Norway. Table S6. Adjusted vaccine effectiveness against SARS-CoV-2 infection by age groups (18-44, 45-64 and ≥65 years) in Norway. Table S7. Adjusted vaccine effectiveness against hospitalisation by age groups (18-44, 45-64 and ≥65 years) in Norway. Table S8. Adjusted vaccine effectiveness against SARS-CoV-2 infection and hospitalisation by vaccine product type. Table S9. Adjusted vaccine effectiveness against SARS-CoV-2 infection and hospitalisation after receiving a booster dose by vaccine product type. Fig. S1. Daily reported cases of SARS-CoV-2 infections and number of hospitalisations, and weekly admissions to ICU and deaths in Norway during the study period, 15 July -30 November 2021. Fig. S2. Distribution of vaccine statuses over time in the study population, 15 July–30 November 2021. Fig. S3. Cohort-wide level of protection against infection over time based on vaccine coverage and vaccine effectiveness estimates. Fig. S4. Vaccine effectiveness against infection and hospitalisations for different vaccine products and combinations of booster doses when splitting the cohort by age.
Croton paraguayensis Chodat, Bull. Herb. Boissier
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Euphorbiaceae
Croton
Croton paraguayensis

description: Croton paraguayensis Chodat, Bull. Herb. Boissier, sér. 2(1): 396. 1901.
Shrub.
 Vouchers: Amambay: Hassler 11279 (BM, K). Central: Hassler 4038, type (A, BM, F, K); Teague 15 (BM). Cordillera: Balansa 4670 (BM, K); Bordas 4371 (K); Degen & Pin 4219 (FCQ); Degen et al. 4198 (FCQ); Ginzbarg 433 (MO); Ginzbarg & Dávalos 432 (MO); Hassler 1866, type (G, K, NY, P); Schinini & Bordas 21260 (G); Vogt & Delmás 513 (FCQ); Zardini 4042 (FCQ, MO); Zardini 6718 (FCQ, MO); Zardini & Degen 3624 (FCQ, MO); Zardini & Salinas 26101 (FCQ, MO). Guairá: (Zuloaga et al. 2015). Paraguarí: Balansa 1649 (K); Brunner & Duré 1039 (MO, PY); Spichiger & Loizeau 1600 (G); Teague 227 (BM); Zardini 12654 (MO, PY); Zardini 12657 (MO, PY); Zardini 5041 (MO, PY); Zardini 7218 (MO, PY); Zardini 8668 (MO, PY); Zardini 8861 (MO, PY); Zardini & Garcete 29113 (MO, PY); Zardini & Guerrero 34986 (MO, PY); Zardini & Pérez de Molas 2781 (MO, PY); Zardini & Pérez de Molas 2785 (MO, PY); Zardini & Tillería 35079 (MO, PY); Zardini & Velásquez 10191 (MO, PY); Zardini & Velásquez 12508 (MO, PY); Zardini & Velásquez 12510 (MO, PY); Zardini & Velásquez 15537 (MO, PY); Zardini et al. 10200 (MO, PY); Zardini et al. 11887 (MO, PY); Zardini et al. 9014 (MO, PY). Unknown: Jörgensen 3519 (MO).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Fractional topological phases in three-dimensional coupled-wire systems
Creators: name: Meng, Tobias
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: It is shown that three-dimensional systems of coupled quantum wires support fractional topological phases composed of closed loops and open planes of two-dimensional fractional quantum Hall subsystems. These phases have topologically protected edge states, and are separated by exotic quantum phase transitions corresponding to a rearrangement of fractional quantum Hall edge modes. Some support for the existence of an extended exotic critical phase separating the bulk gapped fractional topological phases is given. Without electron-electron interactions, similar but unfractionalized bulk gapped phases based on coupled integer quantum Hall states exist. They are separated by an extended critical Weyl semimetal phase.
description: 10 pages, 4 figures
Material suplementario del estudio "La Universitat de València y la práctica de compartir material adicional en las publicaciones científicas"
Creators: name: Sixto-Costoya, Andrea
name: Castelló-Cogollos, Lourdes
name: Valderrama-Zurián, Juan Carlos
name: Aleixandre-Benavent, Rafael
name: Agulló-Calatayud, Víctor
Publisher: name: Zenodo
Year: 2021
Subjects: material adicional
datos compartidos
data sharing
material suplementario
personal investigador y docente (PDI)
publicaciones científicas

description: Material suplementario del estudio sobre el material adicional compartido por el personal docente e investigador (PDI) de la Universitat de València en las publicaciones realizadas en el año 2018. El material suplementario aportado contiene una descripción de las modalidades de material adicional que se han considerado para el estudio y la estrategia seguida para su localizarlo en cada artículo.
The Effect of Age, Race, and Sex on Social Cognitive Performance in Individuals With Schizophrenia
Creators: name: Pinkham, Amy E.
name: Kelsven, Skylar
name: Harvey, Philip D.
name: Penn, David L.
name: Kouros, Chrystyna
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Age, race, and sex are linked to social cognitive performance among healthy individuals, but whether similar effects are evident in schizophrenia is unknown. Data from 170 individuals with schizophrenia or schizoaffective disorder and 98 healthy controls were used to examine relations between these demographic factors and performance across multiple domains and measures of social cognition. Sex was not related to performance on any domain, but older age was related to poorer emotion recognition from dynamic stimuli in both patients and controls. In patients, older age was also associated with better abilities to decipher hints. Both Caucasian patients and controls performed better than African American individuals on emotion recognition and mental state attribution tasks that use only Caucasian individuals as visual stimuli. Findings suggest rather limited influences of demographic factors but do demonstrate normative age and race effects among patients. Findings also highlight important methodological considerations for measurement of social cognition.
Infrared-excess Source DSO/G2 Near the Galactic Center: Theory vs. Observations
Creators: name: Zajacek, Michal
name: Eckart, Andreas
name: Peissker, Florian
name: Karssen, Grischa D.
name: Karas, Vladimir
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Based on the monitoring of the Dusty S-cluster Object (DSO/G2) during its closest approach to the Galactic Center supermassive black hole in 2014 and 2015 with ESO VLT/SINFONI, we further explore the model of a young, accreting star to explain observed spectral and morphological features. The stellar scenario is supported by our findings, i.e. ionized-hydrogen emission from the DSO that remains spatially compact before and after the peribothron passage. The detection of DSO/G2 object as a compact single-peak emission-line source is not consistent with the original hypothesis of a core-less cloud that is necessarily tidally stretched, hence producing a double-peak emission line profile around the pericentre passage. This strengthens the evidence that the DSO/G2 source is a dust-enshrouded young star that appears to be in an accretion phase. The infall of material from the circumstellar disc onto the stellar surface can contribute significantly to the emission of Br$γ$ line as well as the observed large line width of the order of 10 angstrom.
description: 6 pages, 5 figures; to be published in the proceedings of the WDS 2015 organized by the Charles University in Prague. Also presented as a talk at EWASS 2015 (June 25, Special Session: Low-Accretion physics in the Universe), La Laguna, Tenerife, Canary Islands; revised after receiving the comments from referees