cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Baseline characteristics for phase II of the Kinshasa Malaria Cohort Study: cohort profile
Creators: name: Vulu, Fabien
name: Diallo, Alpha Oumar
name: Atibu, Joseph Losoma
name: Kihuma, Georges
name: Mvuama, Nono M
name: Dinglasan, Rhoel
name: Mahilu, Georges Emo
name: Manenga, Faustin
name: White, Samuel J
name: Juliano, Jonathan J
name: Varun, Goel
name: Mwapasa, Victor
name: Banek, Kristin
name: Nkalani, Marthe
name: Nseka, Tommy Mambulu
name: Tshefu, Antoinette Kitoto
name: Bobanga, Thierry
name: Parr, Jonathan B
name: Kashamuka, Melchior Mwandagalirwa
name: Bala, Joseph Alexandre Mavungu
name: Emch, Michael
name: Mampuya, Pitshou Nsongo
Publisher: name: BMJ
Year: 2024

description:
PURPOSE: The Democratic Republic of Congo has one of the highest burdens of malaria in the world, accounting for 12.3% of malaria cases and 11.6% of malaria deaths. The country has been scaling up various malaria control interventions, but how the malaria burden and risk factors have evolved remains unclear. This study aimed to estimate the trend in the burden of malaria in different settings in Kinshasa Province and assess factors contributing to the infection. PARTICIPANTS: From 2018 to 2022, a cohort study was conducted in three health areas in Kinshasa Province known to have varying malaria endemicities: Voix du Peuple (urban), Kimpoko (peri-urban), and Bu (rural) health areas in Kinshasa Province. Participants 6 months of age and older were recruited and followed biannually through household visits and encouraged to visit study health centres whenever they felt ill. The participants' sociodemographic data, illness history and access to malaria interventions were collected along with blood specimens. During the same study period, mosquitoes and larvae were collected to study entomological characteristics that may contribute to malaria transmission. FINDINGS: A total of 1635 participants were recruited from 239 households. The median number of participants per household was 6 (IQR, 5-9). Over half (54.7%) of the participants were female, 14.6% were under-5 children, and 33.3% were 5-14 years old. Household net ownership and reported use the previous night were 77.8% and 79.1%, respectively. Overall, malaria prevalence by rapid diagnostic test at baseline was 33.4%. Of the recruited participants, 1390 (85%) completed the 4 years of follow-up. FUTURE PLANS: Planned analyses include calculating malaria prevalence and incidence trends at follow-up as well as risk factors for infection. Continued analyses will link epidemiological and entomological data to understand malaria transmission evolution and the sustained high prevalence of malaria over time in various settings.
Effect of different training modalities on lipid metabolism in patients with type ii diabetes mellitus: a network meta-analysis
Creators: name: Xing, Shuangtao
name: Xie, Yaming
name: Zhang, Yifan
name: Zhang, Runze
name: Zeng, Dan
name: Yue, Xianfeng
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Science Policy
Hematology

description: This study to evaluate the effects of different training modalities on blood lipids in type II diabetic patients by Network Meta-analysis, and provide a relevant basis for patients to develop exercise prescriptions to regulate blood lipids. Randomized controlled trials (RCTs) were retrieved from Zhiwang, Wanfang, Wipu, PubMed, EBSCO, Cochrane Library, and Web of Science that were published from the establishment to February 2023. Relevant statistical analyses were performed using Stata 17.0 software and Revman 5.4. A total of 35 randomized controlled trials with 2771 patients with type II diabetes were finally included. The results of Network Meta-analysis showed that, compared with the control group, Chinese traditional fitness exercise (CTF), resistance training (RT), and aerobic training (AT) could reduce total cholesterol (TC) levels; CTF, RT, whole body vibration training (WBV), and AT could reduce triacylglycerol (TG) levels; CTF, WBV and AT could increase High-density lipoprotein cholesterol (HDL) levels; CTF, RT and AT could reduce Low-density lipoprotein cholesterol (LDL) levels. SUCRA probability ranking results showed that CTF was the most effective in reducing TC[SMD= −0.57, 95% CI (−0.83, −0.31), p < 0.001], TG[SMD= −0.24, 95% CI (−0.36, −0.12), p < 0.001], LDL[SMD= −0.52, 95% CI (−0.70, −0.35), p < 0.001]; RT was the most effective in increasing HDL[SMD = 0.14, 95% CI (0.03, 0.26), p < 0.05]. CTF is more effective in improving TC, TG and LDL levels, while RT is most effective in improving HDL levels.
Executive Functioning, Family Accommodation, and Treatment Response in Youth with OCD and Comorbid ADHD in a Partial Hospital Program
Creators: name: Walther, Michael
name: O’Connor, Erin
name: Killion, Bryana
name: Cain, Grace H.
name: Benito, Kristen Grabill
name: Freeman, Jennifer B.
name: Marklin, Marika
Publisher: name: Springer Nature
Year: 2024

description:
Few studies have examined differential treatment response, rates of familial accommodation (FA), and executive functioning (EF) in youth with OCD vs. OCD + ADHD, particularly in a partial hospital program (PHP). The current study includes 138 youth diagnosed with OCD only and 102 youth diagnosed with OCD + ADHD in a PHP setting for a total sample of 240 youth (and their families). Families and clinicians completed several measures assessing child and parent variables of interest. Findings of ANCOVA analyses suggest poorer treatment response and EF in children with comorbid OCD + ADHD compared to their counterparts with OCD only. No significant differences emerged between groups in baseline levels of symptom severity, functional impairment, or FA. Given the high rate of comorbidity between OCD + ADHD, clinicians and researchers should be aware of the need to modify treatment approaches for children with comorbid OCD + ADHD and/or weaker EF performance.
Trends in parcel delivery driver injury: Evidence from NEISS-Work
Creators: name: Iacobucci, Evan
name: Naumann, Rebecca
name: Marsh, Suzanne
name: McDonald, Noreen
Publisher: name: Elsevier
Year: 2025

description:
Introduction: The rise of e-commerce has rapidly increased the proportion of goods delivered directly to customers’ homes. These increases have placed notable demands on delivery personnel, with potential health and safety consequences. In this paper, we examined trends in parcel delivery driver injury through analyses of injuries treated in emergency departments (ED) in the United States from 2015 through 2022. Methodology: We explored trends among Couriers and Messengers as well as Postal Service personnel as designated by Bureau of Census (BOC) industry codes. We estimated counts and rates of injuries per 10,000 full time worker equivalents and examined demographics (e.g., age, sex) and other characteristics (e.g., source of injury, injury diagnosis) associated with these injuries. Results: We found that: (1) ED-treated injury rates between 2015 and 2022, among both the Postal Service and Couriers and Messengers, have demonstrated an upward trajectory, contrasting with overall U.S. industry injury rates, which have trended downward; and (2) while ED-treated injury rates for these industries have taken different paths over time, both industries’ ED-treated injury rates have converged toward a position much higher than average. Moreover, we found that female personnel and young personnel disproportionately experienced ED injuries. Conclusions: In addition to calling attention to worrying injury trends among delivery drivers, we conclude that the current data landscape prevents the development of a nuanced picture of injury trends and hazards. These limits inhibit exploration of many specific hazards, and therefore preventive measures that would be designed based on such specific exploration. Practical Applications: Our results serve both as a foundation toward improved safety practices in an industry that continues to experience rapid changes and as a step toward motivating updated data collection and dissemination practices that could help understanding of the modern workplace injury landscape.
The Rise of Nova V1674 Herculis
Creators: name: Corbett, Hank
name: Metzger, Brian D.
name: Shen, Ken J.
name: Quimby, Robert M.
name: Overton, Madeline
name: Shafter, Allen W.
Publisher: name: American Astronomical Society
Year: 2024

description:
Observational constraints on classical novae are heavily biased to phases near optical peak and later because of the simple fact that novae are not typically discovered until they become bright. The earliest phases of brightening, coming before discovery, are typically missed, but this is changing with the proliferation of wide-field optical monitoring systems including the Zwicky Transient Facility, All-Sky Automated Survey for Supernovae, and Evryscope. Here, we report on unprecedented observations of the fast nova V1674 Her beginning >10 mag below its optical peak and including high-cadence (2 minutes) observations that chart a rise of ∼8 mag in just 5 hr. Two clear breaks are identified as the light curve transitions first from rising slowly to rising rapidly, followed by a transition to an even faster, nearly linear rate of increasing flux with time. The depths of the observations allow us to place tight constraints on the size of the photosphere under the assumption of blackbody emission from a white dwarf emitting at its Eddington luminosity. We find that the white dwarf was unlikely to have overflowed its Roche lobe prior to the launch of a fast wind, which poses a challenge for explaining the Fermi γ-ray detections as the interaction of a fast wind with a slow torus of gas stripped from the inflated white dwarf envelope by the companion. High-cadence observations of novae from Evryscope and the planned Argus Array can record the diversity of rising nova light curves and help resolve how the interplay between thermonuclear fusion, binary interaction, and shocks power their earliest light.
A Global MODIS Water Vapor Database for the Operational Atmospheric Correction of Historic and Recent Landsat Imagery
Creators: name: Frantz, David
name: Stellmes, Marion
name: Hostert, Patrick
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: atmospheric correction
subject: analysis ready data
subject: global
subject: Landsat
subject: water vapor
subject: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten

description: This article was supported by the German Research Foundation (DFG) and the Open Access Publication Fund of Humboldt-Universität zu Berlin.
description: Analysis Ready Data (ARD) have undergone the most relevant pre-processing steps to satisfy most user demands. The freely available software FORCE (Framework for Operational Radiometric Correction for Environmental monitoring) is capable of generating Landsat ARD. An essential step of generating ARD is atmospheric correction, which requires water vapor data. FORCE relies on a water vapor database obtained from the Moderate Resolution Imaging Spectroradiometer (MODIS). However, two major drawbacks arise from this strategy: (1) The database has to be compiled for each study area prior to generating ARD; and (2) MODIS and Landsat commissioning dates are not well aligned. We have therefore compiled an application-ready global water vapor database to significantly increase the operational readiness of ARD production. The free dataset comprises daily water vapor data for February 2000 to July 2018 as well as a monthly climatology that is used if no daily value is available. We systematically assessed the impact of using this climatology on surface reflectance outputs. A global random sample of Landsat 5/7/8 imagery was processed twice (i) using daily water vapor (reference) and (ii) using the climatology (estimate), followed by computing accuracy, precision, and uncertainty (APU) metrics. All APU measures were well below specification, thus the fallback usage of the climatology is generally a sound strategy. Still, the tests revealed that some considerations need to be taken into account to help quantify which sensor, band, climate, and season are most or least affected by using a fallback climatology. The highest uncertainty and bias is found for Landsat 5, with progressive improvements towards newer sensors. The bias increases from dry to humid climates, whereas uncertainty increases from dry and tropic to temperate climates. Uncertainty is smallest during seasons with low variability, and is highest when atmospheric conditions progress from a dry to a wet season (and vice versa).
Unexpectedly high variability in determining tumour extent in prostatic biopsies: implications for active surveillance
Creators: name: Bremmer, Felix
name: Kristiansen, Glen
name: Weinhold, Leonie
name: Kreft, Tobias
name: Jufe, Laura
name: Tsuzuki, Toyonori
name: Chan, Emily
name: Schmid, Matthias
name: Iczkowski, Kenneth A
name: Wobker, Sara
name: Oxley, Jon
name: Kweldam, Charlotte
name: Downes, Michelle
name: van Leenders, Geert
name: Reis, Henning
name: Greenland, Nancy
name: Hommerding, Oliver
name: Perry‐Keene, Joanna
name: Collins, Katrina
name: Wiliamson, Sean R
name: Cheng, Liang
name: Bernhardt, Marit
Publisher: name: Wiley
Year: 2024

description:
AIMS: Tumour content in prostatic biopsies is an important indicator of prostate cancer volume and patient prognosis. Consequently, guidelines typically recommend reporting it as a percentage or linear length (mm). This study aimed to determine the current practices for reporting tumour content in prostatic biopsies and evaluated the consistency among pathologists in diagnosing 10 standard biopsy cases of prostate cancer to assess interobserver variability. METHODS AND RESULTS: A web-based survey gathered data on demographics, experience and attitudes regarding the reporting of prostate cancer and its extent in biopsies. Virtual microscopy allowed analysis of 10 biopsy cases, each consisting of a single slide of prostate cancer. Self-reports from 304 participants recruited via the International Society of Urological Pathology and the German Society of Pathology were analysed. Most participants (43.4%) reported tumour extent as percentage of the biopsy core, 37.6% reported percentages and mm and 18.3% reported mm exclusively. The methods used to determine percentages showed an unexpected spread of choices, leading to considerable variability in results. Additionally, 40.8% of participants took part in the practical segment of the survey. The reported measures of tumour extent confirmed a notable interobserver variability, which was significantly higher for reported percentages. CONCLUSION: A high rate of interobserver variability in reporting tumour content in prostatic biopsies was found. This matter is especially critical for patients who are candidates for active surveillance. Reporting absolute measures of tumour content has the advantage of lower variability in comparison to percentages.
Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis
Creators: name: Ishigaki, Kazuyoshi
name: Raychaudhuri, Soumya
name: Huang, Chuan-Chin
name: Wang, Xin
name: Moody, D. Branch
name: Calderon, Roger
name: Zhu, Junhao
name: Murray, Megan B.
name: Li, Xinyi
name: Mayfield, Jacob A.
name: Asgari, Samira
name: Liu, Qingyun
name: Lecca, Leonid
name: Raman, Sahadevan
name: Amariuta, Tiffany
name: Luo, Yang
name: Howard, Nicole C.
name: Fortune, Sarah M.
name: Ramnarine, Alexandrea K.
Publisher: name: Springer Nature
Year: 2024

description:
Infectious disease is the result of interactions between host and pathogen and can depend on genetic variations in both. We conduct a genome-to-genome study of paired human and Mycobacterium tuberculosis genomes from a cohort of 1556 tuberculosis patients in Lima, Peru. We identify an association between a human intronic variant (rs3130660, OR = 10.06, 95%CI: 4.87 − 20.77, P = 7.92 × 10−8) in the FLOT1 gene and a subclavaluee of Mtb Lineage 2. In a human macrophage infection model, we observe hosts with the rs3130660-A allele exhibited stronger interferon gene signatures. The interacting strains have altered redox states due to a thioredoxin reductase mutation. We investigate this association in a 2020 cohort of 699 patients recruited during the COVID-19 pandemic. While the prevalence of the interacting strain almost doubled between 2010 and 2020, its infection is not associated with rs3130660 in this recent cohort. These findings suggest a complex interplay among host, pathogen, and environmental factors in tuberculosis dynamics.
Frailty integration in medical specialties: Current evidence and suggested strategies from the Clin‐STAR frailty interest group
Creators: name: Wysham, Katherine D.
name: Walston, Jeremy D.
name: Faye, Adam S.
name: Kochar, Bharati
name: Shi, Sandra M.
name: Sattui, Sebastian E.
name: Sherman, Andrea N.
name: Singh, Namrata
name: Masters, Mary Clare
name: Loewenthal, Julia V.
name: Lieber, Sarah B.
name: Orkaby, Ariela R.
name: Sheshadri, Anoop
name: Robison, Raele Donetha
name: Iyer, Anand S.
name: Nanna, Michael G.
name: Abidi, Maheen Z.
name: Jain, Nelia
name: Litke, Rachel
name: Grant, Shakira J.
name: DuMontier, Clark
Publisher: name: Wiley
Year: 2024

description:
Frailty is a syndrome that can inform clinical treatments and interventions for older adults. Although implementation of frailty across medical subspecialties has the potential to improve care for the aging population, its uptake has been heterogenous. While frailty assessment is highly integrated into certain medical subspecialties, other subspecialties have only recently begun to consider frailty in the context of patient care. In order to advance the field of frailty-informed care, we aim to detail what is known about frailty within the subspecialties of internal medicine. In doing so, we highlight cross-disciplinary approaches that can enhance our understanding of frailty, focusing on ways to improve the implementation of frailty measures, as well as develop potential interventional strategies to mitigate frailty within these subspecialties. This has important implications for the clinical care of the aging population and can help guide future research.
Temnothorax nylanderi
Creators: name: Gratiashvili, N.
name: Barjadze, S.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Temnothorax
Temnothorax nylanderi

description: 125. T. nylanderi (Foerster, 1850)
Distribution: E.G.: Algeti, Bolnisi, Ertatsminda, Kojori, Khrami gorge, Lagodekhi Reserve, Manglisi, surroundings of Khachini, surroundings of Kianeti, Tetritskaro (Ruzsky, 1905; Jijilashvili, 1967b, 1973, 1974a); S.G.: Abastumani, Akhaldaba, Akhaltsikhe, Baniskhevi, Borjomi Park, Chitakhevhesi, Daba, Dviri, Kariani, Mzetamze, surroundings of Gomareti, surroundings of Patara Dmanisi, surroundings of Sapara, Tsaghveri, Tskhratskaro, Zekari Pass (Ruzsky, 1905; Jijilashvili, 1967a, 1974a).
description: Published as part of Gratiashvili, N. & Barjadze, S., 2008, Checklist of the ants (Formicidae Latreille, 1809) of Georgia., pp. 130-146 in Proceedings of the Institute of Zoology 23 on page 143
Toward target 2035: EUbOPEN - a public–private partnership to enable & unlock biology in the open
Creators: name: Müller, Susanne
name: Sundström, Michael
name: Marsden, Brian D.
name: Willson, Timothy M.
name: Edwards, Aled M.
name: Owen, Dafydd R.
name: Matsui, Hisanori
name: Huber, Kilian V. M.
name: Farin, Henner F.
name: Montel, Florian
name: von Delft, Frank
name: Ackloo, Suzanne
name: Fon, Edward A.
name: Tredup, Claudia
name: Krämer, Oliver
name: Arrowsmith, Cheryl H.
name: Ciulli, Alessio
name: Proschak, Ewgenij
name: Brown, Peter J.
name: Merk, Daniel
name: Kotschy, Andras
name: Isigkeit, Laura
name: Gstaiger, Matthias
name: Stolz, Alexandra
name: Gustavsson, Anna-Lena
name: Mulder, Monique P. C.
name: Knapp, Stefan
name: Leach, Andrew R.
name: Elkins, Jonathan M.
name: Günther, Judith
name: Dikic, Ivan
name: Beck, Hartmut
name: Edfeldt, Kristina
name: Röhm, Sandra
name: Bullock, Alex N.
name: Häberle, Sandra
Publisher: name: Royal Society of Chemistry (RSC)
Year: 2024

description:
EUbOPEN is a public–private partnership focused on four areas: chemogenomic library collection, chemical probe discovery and technology development, compound profiling in patient-derived assays, and data and reagents collection, storage and sharing. Target 2035 is a global initiative that seeks to identify a pharmacological modulator of most human proteins by the year 2035. As part of an ongoing series of annual updates of this initiative, we summarise here the efforts of the EUbOPEN project whose objectives and results are making a strong contribution to the goals of Target 2035. EUbOPEN is a public–private partnership with four pillars of activity: (1) chemogenomic library collections, (2) chemical probe discovery and technology development for hit-to-lead chemistry, (3) profiling of bioactive compounds in patient-derived disease assays, and (4) collection, storage and dissemination of project-wide data and reagents. The substantial outputs of this programme include a chemogenomic compound library covering one third of the druggable proteome, as well as 100 chemical probes, both profiled in patient derived assays, as well as hundreds of data sets deposited in existing public data repositories and a project-specific data resource for exploring EUbOPEN outputs.
Temnothorax parvulus
Creators: name: Gratiashvili, N.
name: Barjadze, S.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Temnothorax
Temnothorax parvulus

description: 126. T. parvulus (Schenck, 1852)
Distribution: E.G.: Kavtiskhevi, Kiketi, Manglisi, Saguramo, Shulaveri, Tbilisi (Mtatsminda park), Tskneti, Tsodoreti, Zedazeni (Jijilashvili, 1964b, 1966, 1968).
description: Published as part of Gratiashvili, N. & Barjadze, S., 2008, Checklist of the ants (Formicidae Latreille, 1809) of Georgia., pp. 130-146 in Proceedings of the Institute of Zoology 23 on page 143
EXPERIMENTAL AND TECHNO-ECONOMIC EVALUATION OF THE HYDROGENATION/DEHYDROGENATION OF DIBENZYL TOULUENE IN A MEMBRANE REACTOR TO FACILATAE THE TRANSPORT OF RENEWABLE HYDROGEN
Creators: name: Almutawa, Abdullah
Publisher: name: Washington State University
Year: 2021

description: Liquid Organic Hydrogen Carriers (LOHC) are gaining interest for the role they can play in facilitating the storage and transport of renewable hydrogen over long distances from areas where renewable energy is inexpensive and abundant to areas with high demand, for example from Australia to Japan. High energy density and ease of handling favor conversion of hydrogen to a hydrogenated organic molecule in liquid form. The hydrogenation/dehydrogenation and transport conditions and processing of LOHC as well as the energy density of the organic carriers must be energetically and economically favorable compared to simply storing/transporting molecular hydrogen (H2), likely under high pressure and/or cryogenic conditions. Dibenzyl toluene as a LOHC can store hydrogen at high capacity with moderate reaction conditions for hydrogenation/dehydrogenation, typically 50 bar and 200 °C for hydrogenation and ambient pressure and 300 °C for dehydrogenation. Despite the moderate temperature and pressure required during this process when performed in conventional reactors, the process is less energy efficient than the existing method adapted currently in industry by compression hydrogen to high pressures. An ambient pressure low temperature hydrogenation process using a membrane reactor is studied here experimentally and, in a techno-economic evaluation based on material- and energy balances. Initial experiments point towards successful hydrogenation of an LOHC in a membrane reactor using metal decorated high performance integral-asymmetric membranes. The techno-economic evaluation showed that by using the membrane reactor energy and cost can be reduced by 47.4% in comparison to the conventional LOHC pressurized reactor, and by 13% in comparison to the compressed hydrogen storage method.
Temnothorax recedens
Creators: name: Gratiashvili, N.
name: Barjadze, S.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Temnothorax
Temnothorax recedens

description: 127. T. recedens (Nylander, 1856)
Syn.: Leptothorax (Temnothorax) rogeri Em.
Distribution: E.G.: surroundings of Mtskheta (Ruzsky, 1905; surroundings of Kutaisi (Ruzsky, 1905, 1907); S.G.: Borjomi (Ruzsky, 1905).
description: Published as part of Gratiashvili, N. & Barjadze, S., 2008, Checklist of the ants (Formicidae Latreille, 1809) of Georgia., pp. 130-146 in Proceedings of the Institute of Zoology 23 on page 143
Temnothorax satunini
Creators: name: Gratiashvili, N.
name: Barjadze, S.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Temnothorax
Temnothorax satunini

description: 128. T. satunini (Ruzsky, 1902)
Distribution: E.G.: Gardabani, Rustavi (Jijilashvili, 1968).
description: Published as part of Gratiashvili, N. & Barjadze, S., 2008, Checklist of the ants (Formicidae Latreille, 1809) of Georgia., pp. 130-146 in Proceedings of the Institute of Zoology 23 on page 143
Implementing analytical quality by design in reversed phase-high performance liquid chromatography for simultaneous estimation of teriflunomide and quercetin: Applicability in dual drug loaded topical microemulsion
Creators: name: Karnam, Sriravali
name: Jindal, Anil B.
name: Paul, Atish T.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The current study reports the development of a novel, robust, and sensitive reversed-phase high-performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of teriflunomide (TFD) and quercetin (QCN) in dual drug-loaded microemulsion. TFD and QCN have been reported to exhibit anti-inflammatory effects by targeting various inflammatory mediators involved in the pathogenesis of rheumatoid arthritis (RA). This analytical method employs a risk-based approach and follows the principles of analytical quality by design (AQbD). The study involved preliminary screening trials and systematic risk analysis to identify critical method attributes, that significantly impact the critical quality attributes (CQAs). For the optimization of method,a face centered central composite design was utilized, and 16 experimental runs were performed using design expert software version 7.0.0. Chromatographic conditions were carefully optimized using AQbD, falling within the design space and consisting of ammonium acetate buffer (pH 3.5) and acetonitrile (60:40, % v/v) with a flow rate of 1.0 mL/min. An analytical Hibar Lichospher 100 RP-18e column (250 × 4.6 mm, 5 µm) was employed, with detection wavelength of 280 nm and 367 nm for TFD and QCN, respectively. The optimized method underwent validation according to ICH guidelines and demonstrating applicability for evaluating topical microemulsion.
Formica tamarae
Creators: name: Gratiashvili, N.
name: Barjadze, S.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Formica
Formica tamarae

description: 129. T. tamarae (Radchenko, 1993)
Distribution: S.G.: Tsaghveri (Radchenko, 1993).
description: Published as part of Gratiashvili, N. & Barjadze, S., 2008, Checklist of the ants (Formicidae Latreille, 1809) of Georgia., pp. 130-146 in Proceedings of the Institute of Zoology 23 on page 143
Integrated UPLC-MS and multivariate data processing approach to explore the chemical components of Uncaria rhynchophylla and its absorbed components in rats following oral adminstration
Creators: name: Yu, Yongzhou
name: Xiong, Hui
name: Chen, Siruan
name: Meng, Jie
name: Xu, Yanmei
name: Li, Na
name: Yang, Jian
name: Liu, Yunxia
name: Wu, Wei
name: Li, Zirou
name: Zhang, Wei
name: Cui, Xiaoyan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese, UR), a common herbal medicine, is chosen for treating cerebral diseases such as convulsions, hypertension, epilepsy, and eclampsia. However, comprehensive research on the chemical components of UR and its absorbed components has not been revealed. To develop an integrative UP LC-Q-TOF-MS and multivariate data processing approach for determining the chemical constituents of UR and its absorbed constituents in rat serum after oral adminstration. A UP LC-Q-TOF-MS equipped with a Waters UP LCT M HSS T3 was applied for sample seperation. P CA and OP LS-DA were applied to extract differential variables. Based on the self-built databases combined with mass spectrometry cleavage patterns and reference standards, the components structural identification were carried out. In total, 40 compounds, including alkaloids, flavonoids, terpenoids were identified in UR. Amongst them, 26 prototype constituents were found in rat serum, which might be the potential active constituents.The identified constituents absorbed in blood could be the effective constituents. This work provided a solid experimental data for further research on the pharmacological substance basis and demonstrated the practicability of the UP LC-Q-TOF-MS for chemical constituents structural elucidation from herbal medicines.
Achnanthidium peruvianum E. Morales & Ector
Creators: name: Costa, Lívia F.
name: Wetzel, Carlos E.
name: Maquardt, Gisele C.
name: Zanon, Jaques E.
name: Ector, Luc
name: Bicudo, Denise C.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Chromista
Bacillariophyta
Bacillariophyceae
Achnanthales
Achnanthidiaceae
Achnanthidium
Achnanthidium peruvianum

description: Achnanthidium peruvianum E.Morales & Ector in Morales et al. (2011: 121) (Figs 166–193)
Synonym: Achnanthes kryophiloides M.H.Hohn in Patrick et al. (1966), p. 468, pl. 1, Figs 5, 6
Morphometric features:— 8.0–20.2 µm long; 2.3–4.3 µm wide; 28–34 striae in 10 µm; striae mainly composed of 4–5 areolae.
Taxonomical remarks:— The species presents similar morphological features to another South American species called Achnanthidium sehuencoensis, which has almost the same valve outline. However, SEM analysis separated the two due to the deflected terminal raphe fissures, the non-expanded central raphe fissures, and lower stria density (20–24/10 µm, Morales et al. 2009) compared to A. peruvianum.
Achnanthidium petersenii (Hustedt) C.E.Wetzel, Ector & Jüttner (in Jüttner et al. 2019: 66) has wider fascia on the raphe valve. However, on the rapheless valves, the axial area is moderately broad, and the central area broadly rhombic-lanceolate (Jüttner et al. 2019). In A. peruvianum, the axial area is narrow and linear, while the central area is undifferentiated with short striae (Morales et al. 2011).
Distribution and ecological information:— Achnanthidium peruvianum was described from the Rondos River in Peru, South America (Hohn in Patrick et al. 1966). In our samples, the species was rare (abundance <3 %), occurring in less than 5 % of the counted samples in planktonic and surface sediment assemblages. In the surface sediment, it showed ecological preferences for neutral (pH optimum of 6.9), electrolyte-poor (optimum of 30.8 μS∙ cm-1), and oligotrophic environmental water conditions (TP optimum of 18.4 μg∙L- 1 and TN optimum of 372.5 μg∙L- 1).
description: Published as part of Costa, Lívia F., Wetzel, Carlos E., Maquardt, Gisele C., Zanon, Jaques E., Ector, Luc & Bicudo, Denise C., 2022, Taxonomy and ecology of Achnanthidium (Bacillariophyta, Achnanthidiaceae) from southeastern Brazil with the description of six new species, pp. 187-223 in Phytotaxa 575 (3) on page 207, DOI: 10.11646/phytotaxa.575.3.1, http://zenodo.org/record/7431242
Temnothorax tuberum
Creators: name: Gratiashvili, N.
name: Barjadze, S.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Temnothorax
Temnothorax tuberum

description: 130. T. tuberum (Fabricius, 1775)
Distribution: E.G.: Kavtiskhevi, surroundings of Bolnisi, Tbilisi (Mtatsminda plateau, Tbilisi Botanical Garden) (Jijilashvili, 1968, 1973, 1974a); W.G.: Akhali Atoni, Batumi (Ruzsky, 1905).
description: Published as part of Gratiashvili, N. & Barjadze, S., 2008, Checklist of the ants (Formicidae Latreille, 1809) of Georgia., pp. 130-146 in Proceedings of the Institute of Zoology 23 on page 143
Distinguishing the intrinsic differences of Cynomorium songaricum from different origins using chemical fingerprinting combined with chemometric methods
Creators: name: Yin, Yu
name: Liu, Mei-qi
name: Zhao, Xiao-ran
name: Qiu, Zi-ying
name: Wei, Xue-rou
name: Sun, Li-li
name: Deng, Yan-ru
name: Liu, Ya-nan
name: Ren, Xiao-liang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Cynomorium songaricum is a commonly used medicinal and culinary plant renowned for its effects in tonifying kidney yang, as well as nourishing essence and blood. Consequently, it has garnered considerable attention within the fields of pharmacology and chemistry. However, given the distinct geographical distribution of C. songaricum resources, establishing an accurate analytical method to differentiate its origin becomes indispensable in ensuring its quality and efficacy. In this study, high-performance liquid chromatography (HPLC) was utilized to obtain comprehensive information on the chemical composition of C. songaricum samples from various regions and establish HPLC fingerprints. Through chemometrics analysis, essential chemical markers for classifying them were successfully identified. Additionally, the Kruskal–Wallis rank sum test was employed to evaluate differences in the content of intrinsic constituents of C. songaricum from different origins. The results demonstrated that C. songaricum samples from Neimenggu, Gansu, and Xinjiang could be accurately classified, highlighting the significance of chemical markers in assessing the quality of C. songaricum. This study provides a scientific basis for systematic quality control of Chinese herbal medicines, thereby contributing to advancements in the Chinese medicine industry.
Exploring volatile organic profiles of red pen inks based on gas-chromatography-flame ionization detection (GC-FID) and chemometric methods for forensic investigation purposes
Creators: name: Amnuai, Cherayna
name: Lee, Siew Wei
name: Zamani, Norwahida
name: Sino, Hukil
name: Lee, Loong Chuen
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Criminal cases involving questioned documents often cause the loss of a huge amount of money in a country. Red ballpoint pen inks found on threatening notes, or any official documents are potentially encountered by a forensic document examiner as questioned documents. Identifying sources of the questioned ink entries is paramount to revealing the authenticity or sources of the document. Despite the multitude of works being devoted to discriminating pen inks by their sources, very little is focused on the volatile fractions. In this study, the volatile compositional profiles of ten types of red ballpoint pen inks as acquired by gas chromatography-flame ionization detection (GC-FID) were studied using various multivariate exploratory tools. Scores plot of principal component analysis reveals that inter-pen brand variation is higher than the inter-pen type variation. Meanwhile, hierarchical clustering analysis showed that 6 of the 10 pen types and all five pen brands could be discriminated. In conclusion, volatile organic compositions of red pen inks are useful in classifying the pen inks by brands. The outcome of the study will provide vital insight into the potential of volatile organic profiles in discriminating red pen inks sold in Malaysia.
Folsomides
Creators: name: Arbea, Javier I.
name: Jordana, Rafael
Publisher: name: Zenodo
Year: 2002
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Isotomidae
Folsomides

description: Key of Folsomides species in the Ibero­balearic fauna
(A summary of the main diagnostic characteristics of the species is given in Table 2)
1. Mucro absent (F. nanus ­group) .................................................................................................. 2
­ Mucro present ............................................................................................................................ 3
2. With 5+5 corneola. Microsensilla: 11/111. Dens with 2 dorsal chaetae and 1 ventro­apical chaeta. Retinacle with 3+3 teeth and 1 chaeta on the corpus ........................................................... ....................................................................................... F. ayllonensis Simón & Luciáñez, 1990
­ With 2+2 corneola. Microsensilla: 10/000. Dens with 2 dorsal chaetae and no ventro­apical chaeta. Retinacle with 2+2 teeth and 1 chaeta on the corpus ....................................................... ................................................................................... F. almanzorensis Luciáñez & Simón, 1991
3. With 1­2+1­2 corneoles. Long and very narrow postantennal organ. Microsensillae: 10/001.
description: Published as part of Arbea, Javier I. & Jordana, Rafael, 2002, The genus Folsomides Stach of the Ibero­balearic fauna, with description of a new species (Collembola, Isotomidae), pp. 1-8 in Zootaxa 55 on page 6, DOI: 10.5281/zenodo.156067
title: Taoist AI: Adaptive and Effortless Cyber Defense
title: Harnessing Adaptive Intelligence for Seamless and Resilient Cybersecurity
titleType: Subtitle
Creators: name: Kallol, Chakrabarti
Publisher: name: Zenodo
Year: 2025

description: Taoist AI represents a revolutionary approach to cybersecurity, characterized by its adaptability, real-time monitoring, and automated response capabilities. Unlike conventional cybersecurity models, Taoist AI emphasizes fluid and effortless defense mechanisms, aligning with the principles of Taoism. This paper explores the core attributes of Taoist AI, its advantages, and its impact on cybersecurity and society. Additionally, a comparative analysis of Stoic AI, Buddhist AI, and Taoist AI is provided to highlight the strengths and weaknesses of each philosophy in cybersecurity. The integration of these philosophical models can lead to a balanced and comprehensive security strategy.
Potential of WebAssembly for Embedded Systems
Creators: name: Wallentowitz, Stefan
name: Kersting, Bastian
name: Dumitriu, Dan Mihai
Publisher: name: arXiv
Year: 2024
Subjects: subject: Operating Systems (cs.OS)
subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: Application virtual machines provide strong isolation properties and are established in the context of software portability. Those opportunities make them interesting for scalable and secure IoT deployments. WebAssembly is an application virtual machine with origins in web browsers, that is getting rapidly adopted in other domains. The strong and steadily growing ecosystem makes WebAssembly an interesting candidate for Embedded Systems. This position paper discusses the usage of WebAssembly in Embedded Systems. After introducing the basic concepts of WebAssembly and existing runtime environments, we give an overview of the challenges for the efficient usage of WebAssembly in Embedded Systems. The paper concludes with a real world case study that demonstrates the viability, before giving an outlook on open issues and upcoming work.
DYNAMIC STABILITY ASSESSMENT AND ENHANCEMENT IN THE NIGERIAN 330 KV, 36-BUS ELECTRICITY GRID NETWORK VIA COMBINED USE OF GOVERNOR AND POWER SYSTEM STABILIZER
Creators: name: Rufus, Akinnusimi Jokojeje
name: Isaiah, Adediji Adejumobi
name: Oluwaseun, Ibrahim Adebisi
name: Idowu Ademola, Osinuga
Publisher: name: ZAP journals
Year: 2024
Subjects: Small signal or dynamic instability Eigenvalues
Governor
Power System Stabilizer
Rotor Angle

description: Small signal or dynamic instability is one of the major challenges experienced in the operation of power systems, which often results in the violation of acceptable voltage and frequency limits. Therefore, this study assessed small signal stability on a power system via an eigenvalues approach. Non-linear differential-algebraic equations describing the dynamic characteristics of the power system were developed. These equations were linearized using Taylor’s series expansion. The computational algorithm with eigenvalues was developed considering the Nigerian 330 kV electricity grid comprising 13 generators and 36 busses as test system. The qualitative stability state of the system was determined by obtaining the eigenvalues of the generator rotor angle ()  parameters with and without control schemes implemented via the governor (G) and the governor with the power system stabilizer (G + PSS). The results showed that   was in stable state for all 13 generators in the network with eigenvalues obtained having negative real parts with and without controllers; although a better system stability level was obtained with G + PSS compared to G because the real part of the obtained eigenvalues was much lower in value. This result clearly revealed that G + PSS exhibited superiority over G in improving the small signal stability of the considered power network. The use of eigenvalues produced a simplified analysis of the small signal stability of a power system network where the combined effect of the governor and power system stabilizer offered better stability enhancement.
U.S. CONSUMER PREFERENCE AND POLICY IN BEV 2018-2020
Creators: name: Rouleau, Nicole Renee
Publisher: name: Washington State University
Year: 2022
Subjects: consumer
electric
policy
preference
subsidy
vehicle

description: Battery electric vehicles have gained market growth in the United States due to government policies and consumer preferences. Government policy can be an incentive to consumers purchasing electric vehicles, but if consumer preference was strong enough would these incentives still be required? In the retail market, consumer preferences have shown to be strong enough to not require incentives in "green" products. The consumer preferences for “green” retail products could imply that the automotive market may work similarly and that incentives may not be necessary for the purchase of electric vehicles. However, the automotive market has higher costs that may dissuade consumers and require incentives for decision making.
Longing
Creators: name: Hunnicutt, Autumn
Publisher: name: Washington State University
Year: 2022
Subjects: Conceptual Portrait
Contemporary Figurative
Fine Art
Oil Painting

description: Longing is an interpretation of a matriarchal genealogy pertaining to women in my immediate family. The goal of this body of work is to create a narrative that deviates from a specific space or time. It is honoring each woman for their own experience in life while simultaneously connecting them through elements that exist in different dimensions: the physical and the ethereal planes of the unknown. Longing places myself alongside the women who came before me, plucked from different timelines, not only to narrate their existence in a familiar place but to elevate the strength and wisdom gained through generational experiences. Stemming three generations, this series assigns each woman their own elements from nature based on my own memories with them, in turn constructing a familial mythology they share while maintaining their own unique individualism. My work explores the beauty of memory, emotion, interconnection, and cyclical patterns influenced by the colors, landscapes, plants, and animals of the southwest.
Classifying Lower Body Extensor Strength Qualities in Field Sport Athletes
Creators: name: Geneau, Mary Claire
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 420701
subject: Biomechanics
classificationCode: 420702
subject: Exercise physiology
classificationCode: 420799
subject: Sports science and exercise not elsewhere classified

description: Submitted in total fulfillment of the requirements for the degree of Doctor of Philosophy to the School of Allied Health, Human Services and Sport, La Trobe University, Victoria, Australia.
Temnothorax unifasciatus
Creators: name: Gratiashvili, N.
name: Barjadze, S.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Temnothorax
Temnothorax unifasciatus

description: 131. T. unifasciatus (Latreille, 1798)
Syn.: Leptothorax tuberum unifasciatus (Latr.) var. anoplogynus Em.
Distribution: E.G.: Kavtiskhevi, Kiketi, Lagodekhi Reserve, Manglisi, Poladauri, surroundings of Bolnisi, surroundings of Mtskheta, surroundings of Ratevani, surroundings of Tetritskaro, Zedazeni (Ruzsky, 1905; Karavaev, 1926; Jijilashvili, 1964b, 1966, 1967b, 1968, 1974a); W.G.: Alakhadze, Anaklia, Asechka, Baghdati, Bichvinta, Bjinevi, Chakvistavi, Gagra, Khobi, Kutaisi, Lidzava, Poti, riv. Tekhura and Rioni, without exact locality, Sakara, Senaki, surroundings of Achishesi, Tsaishi, Zugdidi Botanical Garden (Ruzsky, 1905, 1907; Karavaiev, 1926; Jijilashvili, 1974b); S.G.: Akhaldaba, Borjomi Park, Chitakhevhesi, Chobiskhevi, Daba, Kimotesubani, Tsaghveri, Zekari pass (Ruzsky, 1905; Jijilashvili, 1967a, 1974a).
description: Published as part of Gratiashvili, N. & Barjadze, S., 2008, Checklist of the ants (Formicidae Latreille, 1809) of Georgia., pp. 130-146 in Proceedings of the Institute of Zoology 23 on page 143