cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Characterization of fractional Sobolev--Poincaré and (localized) Hardy inequalities
Creators: name: Sk, Firoj
Publisher: name: arXiv
Year: 2022
Subjects: subject: Analysis of PDEs (math.AP)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 46E35, 35A23, 42B25, 31B15

description: In this paper, we prove capacitary versions of the fractional Sobolev--Poincaré inequalities. We characterize localized variant of the boundary fractional Sobolev--Poincaré inequalities through uniform fatness condition of the domain in $\mathbb{R}^n$. Existence type results on the fractional Hardy inequality are established in the supercritical case $sp>n$ for $s\in(0,1)$, $p>1$. Characterization of the fractional Hardy inequality through weak supersolution of the associate problem is also addressed.
description: 19 pages, We removed theorem 1.12 from the 1st version of the paper. There were some incorrect results and arguments. We correct them all, especially in the proof of theorem 1.9
Das Landesmodul Schleswig-Holstein im Rahmen des Kinder- und Jugendgesundheitssurveys (KiGGS)
Creators: name: Kamtsiuris, Panagiotis
name: Lange, Michael
name: Rosario, Angelika Schaffrath
name: Kurth, Bärbel-Maria
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2007
Subjects: subject: Humans
subject: Adolescent
subject: Germany
subject: Child
subject: Female
subject: Male
subject: Research Design
subject: Sampling Studies
subject: Patient Selection
subject: Emigration and Immigration/statistics & numerical data
subject: Health Surveys*
subject: 610 Medizin

description: Von August 2004 bis Juni 2005 führte das Robert Koch-Institut im Rahmen des Kinder- und Jugendgesundheitssurveys (KiGGS) die Feldarbeit für das Schleswig-Holstein-Modul durch. Die KiGGS-Studie ist ein bundesweit repräsentativer Survey zum Gesundheitszustand von Kindern und Jugendlichen im Alter von 0–17 Jahren. Die Modul-Studie ermöglicht durch eine Stichprobenaufstockung in Schleswig-Holstein bei den 11- bis 17-Jährigen repräsentative Aussagen für dieses Bundesland. Zu diesem Zweck wurden in der Modul-Studie zusätzlich zu den 5 Schleswig-Holsteiner Untersuchungsorten der Kern-Studie weitere 18 Orte in diesem Bundesland einbezogen und ein im Vergleich zur Kern-Studie leicht reduziertes Untersuchungsprogramm umgesetzt. Insgesamt wurden in Schleswig-Holstein 1931 Probanden untersucht, davon 1730 im Landesmodul und 201 in der Kern-Studie. Die Teilnahmequote lag in der Modul-Studie bei 69,5%. Der Anteil qualitätsneutraler Ausfälle betrug 4,0%. Das Landesmodul wurde durch das Ministerium für Soziales, Gesundheit, Familie, Jugend und Senioren des Landes Schleswig-Holstein finanziert. Die Daten werden für die Gesundheitsberichterstattung auf Landesebene genutzt. Schlüsselwörter Gesundheitssurvey - Kinder - Jugendliche - Schleswig-Holstein - Modul
description: From August 2004 to June 2005, the Robert Koch Institute conducted the fieldwork for the Schleswig-Holstein module of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS). The KiGGS study is a nationwide representative survey of the health of children and adolescents aged 0 to 17 years. By increasing the sample size in the age group 11 to 17 years in Schleswig-Holstein, the module study generated information which is representative for this federal state. For this end, further 18 locations in this federal state were included in the module study in addition to the existing 5 study locations in Schleswig-Holstein and a study programme which was slightly reduced compared to the core survey was realised. A total of 1,931 subjects were examined in Schleswig-Holstein: 1,730 in the federal state module and 201 in the core survey. The participation rate was 69.5% in the module study. The percentage of quality-neutral drop-outs was 4.0%. The federal state module was funded by the Ministry of Social Welfare, Health, Family, Youth and Seniors of the Federal State of Schleswig-Holstein. The data collected were used for health reporting on a federal state level.
Description of the early stage of pandemic (H1N1) 2009 in Germany, 27 April-16 June 2009
Creators: name: Alpers, Katharina
name: Altmann, Doris
name: Heiden, Matthias An Der
name: Bartels, Cornelius
name: Bätzing-Feigenbaum, Jörg
name: Becker, Anne
name: Behnke, Susanne
name: Bergholz, Andreas
name: Bernard, Helen
name: Bielecke, Jessica
name: Biere, Barbara
name: Böhmer, Merle
Publisher: name: Robert Koch-Institut
Year: 2009
Subjects: subject: Humans
subject: Adolescent
subject: Adult
subject: Aged
subject: Middle Aged
subject: Child
subject: Female
subject: Infant
subject: Male
subject: Influenza
subject: Germany/epidemiology
subject: Travel
subject: Age Distribution
subject: Disease Outbreaks
subject: Sex Distribution
subject: Preschool
subject: Influenza A Virus
subject: H1N1 Subtype
subject: isolation & purification Influenza
subject: Human/complications
subject: Human/diagnosis
subject: Human/epidemiology
subject: Population Surveillance
subject: Young Adult
subject: 610 Medizin

description: We report characteristics of the early stage of the pandemic (H1N1) 2009 in Germany. Until 16 June 2009, 198 confirmed cases were notified. Almost half of the cases (47%) were imported, mostly from Mexico and the United States. About two third of indigenous cases were outbreak-related (with two large school-associated outbreaks, n=74). According to our results Germany is still in the early stage of the pandemic with limited domestic transmission.
Humane embryonale Stammzellen im Kontext internationaler Forschungsaktivitäten
Creators: name: Wobus, Anna M.
name: Löser, Peter
Publisher: name: Robert Koch-Institut, Stammzellen
Year: 2008
Subjects: subject: Humane embryonale Stammzellen
subject: hES-Zellen
subject: Charakterisierung
subject: Forschungsnetzwerke
subject: Anwendung
subject: Human embryonic stem cells
subject: hESCs
subject: characterization
subject: research networks
subject: application
subject: 610 Medizin

description: Forschung an pluripotenten humanen embryonalen Stamm (hES)-Zellen ist ein rasch wachsendes Wissenschaftsgebiet. Aufgrund der Herkunft des Zellmaterials aus frühen menschlichen Embryonen wurden alternative Verfahren zur Gewinnung von pluripotenten Zellen entwickelt. Der Beitrag stellt einige dieser Strategien vor und behandelt darüber hinaus die internationalen Bestrebungen, einheitliche Standards für die Kultivierung, Charakterisierung und Lagerung von hES-Zellen zu etablieren. Ferner werden die weltweiten Tendenzen zur Bildung von Netzwerken auf dem Gebiet der Stammzellforschung sowie Bestrebungen zur Harmonisierung ethischer Standards bei der Arbeit mit hES-Zellen aufgezeigt. Schließlich werden Perspektiven der Verwendung von hES-Zellen in der pharmakologisch-toxikologischen Forschung sowie jüngste Ergebnisse tierexperimenteller Studien mit hES-Zellen diskutiert.
description: Research involving pluripotent human embryonic stem cells (hESCs) is a rapidly growing field of science. Since hESCs originate from early human embryos, alternative methods for producing pluripotent cells have been developed. This article introduces some of those strategies and, in addition, covers international efforts to establish consistent international standards for cultivation, characterization and preservation of hESCs. Furthermore, global trends to form networks in the field of stem cell research as well as endeavors to harmonize ethical standards for hESC research are presented. Finally, potential applications of hESCs in the field of pharmacology/toxicology are discussed as well as recent results of animal studies using hESCs.
Discovery of herpesviruses in multi-infected primates using locked nucleic acids (LNA) and a bigenic PCR approach
Creators: name: Prepens, Sandra
name: Kreuzer, Karl-Anton
name: Leendertz, Fabian
name: Nitsche, Andreas
name: Ehlers, Bernhard
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger; Robert Koch-Institut, Biologische Sicherheit
Year: 2007
Subjects: subject: Animals
subject: DNA
subject: Molecular Sequence Data
subject: Phylogeny
subject: Cluster Analysis
subject: Herpesviridae Infections/veterinary
subject: Viral/genetics
subject: Sequence Analysis
subject: Viral Proteins/genetics
subject: Polymerase Chain Reaction/methods
subject: Primate Diseases/virology
subject: DNA Primers/genetics
subject: Glycoproteins/genetics
subject: Virology/methods
subject: Herpesviridae Infections/virology
subject: Viral/chemistry
subject: Herpesviridae/genetics
subject: Herpesviridae/isolation & purification
subject: Herpesviridae/classification
subject: DNA-Directed DNA
subject: Polymerase/genetics
subject: Exodeoxyribonucleases/genetic
subject: Primates
subject: Viral Structural Proteins/genetics
subject: 610 Medizin

description: Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses. However, vertebrate hosts are often infected with more than one herpesvirus in the same tissue, and pan-herpes DPOL PCR often favors the amplification of one viral sequence at the expense of the others. Here we present two different technical approaches that overcome this obstacle: (i) Pan-herpes DPOL PCR is carried out in the presence of an oligonucleotide substituted with locked nucleic acids (LNA).This suppresses the amplification of a specific herpesvirus DPOL sequence by a factor of approximately 1000, thereby enabling the amplification of a second, different DPOL sequence. (ii) The less conserved glycoprotein B (gB) gene is targeted with several sets of degenerate primers that are restricted to gB genes of different herpesvirus subfamilies or genera. These techniques enable the amplification of gB and DPOL sequences of multiple viruses from a single specimen. The partial gB and DPOL sequences can be connected by long-distance PCR, producing final contiguous sequences of approximately 3.5 kbp. Such sequences include parts of two genes and therefore allow for a robust phylogenetic analysis. To illustrate this principle, six novel herpesviruses of the genera Rhadinovirus, Lymphocryptovirus and Cytomegalovirus were discovered in multi-infected samples of non-human primates and phylogenetically characterized.
Minor drug-resistant HIV type-1 variants in breast milk and plasma of HIV type-1-infected Ugandan women after nevirapine single-dose prophylaxis
Creators: name: Pilger, Daniel
name: Hauser, Andrea
name: Kücherer, Claudia
name: Mugenyi, Kizito
name: Kabasinguzi, Rose
name: Somogyi, Sybille
name: Harms, Gundel
name: Kunz, Andrea
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2010
Subjects: subject: Adult
subject: Humans
subject: Female
subject: Pregnancy
subject: Cohort Studies
subject: Genetic Variation
subject: HIV Infections/drug therapy
subject: HIV Infections/transmission
subject: HIV-1/drug effects
subject: HIV-1/genetics
subject: Uganda
subject: Infant Newborn
subject: HIV Infections/prevention & control
subject: Anti-HIV Agents/therapeutic use
subject: Nevirapine/therapeutic use
subject: HIV Infections/virology
subject: Anti-HIV Agents/administration & dosage
subject: Drug Resistance Viral/drug effects
subject: Drug Resistance Viral/genetics
subject: HIV Infections/genetics
subject: Infectious Disease Transmission Vertical/prevention & control
subject: Milk Human/chemistry
subject: Milk Human/drug effects
subject: Milk Human/virology
subject: Mutation/drug effects
subject: Nevirapine/administration & dosage
subject: Post-Exposure Prophylaxis
subject: Pregnancy Complications Infectious/drug therapy
subject: Pregnancy Complications Infectious/prevention & control
subject: Pregnancy Complications Infectious/virology
subject: 610 Medizin

description: Background: Nevirapine single-dose (NVP-SD) reduces mother-to-child transmission of HIV type-1 (HIV-1), but frequently induces resistance mutations in the HIV-1 genome. Little is known about drug-resistant HIV-1 variants in the breast milk of women who have taken NVP-SD. Methods: Blood and breast milk samples of 39 HIV-1-infected Ugandan women were taken 6–12 weeks after NVP-SD intake. Samples were analysed by population sequencing and allele-specific real-time PCR (AS-PCR) with detection limits for NVP-resistant HIV-1 variants (K103N and Y181C) of 1 drug-resistant variant. Resistance in breast milk was higher at week 6 (6/13 samples [46%]) compared with week 12 (1/6 samples [17%]). In total, 10 drug-resistant populations harbouring the K103N and/or Y181C mutation were detected in the 19 breast milk samples; 7 (70%) were caused by resistant minorities (
Detektion von bioterroristisch relevanten Toxinen am Beispiel Rizin
Creators: name: Dorner, Brigitte
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2011
Subjects: subject: GERMAN BIOSAFETY 2005
subject: Toxine
subject: Rizin
subject: 610 Medizin

description: Zu den giftigsten bekannten Pflanzentoxinen gehört Rizin, das in den Samen des Wunderbaums Ricinus communis enthalten ist. Obwohl die Toxizität des Rizins etwa tausendfach geringer ist als die des Botulinumtoxins, zählt Rizin zu den im Zusammenhang mit B-Kampfstoffen am häufigsten genannten Toxinen. Dies liegt zum einen am ubiquitären Vorkommen der Pflanze und deren großtechnischer Nutzung zur Herstellung von Rizinusöl. Zum anderen ist die Präparation des Toxins aus den Pflanzensamen technisch relativ einfach. Außerdem gibt es im Falle einer Intoxikation bislang noch keine wirksamen Gegenmittel. Angriffe auf Einzelpersonen mittels Rizins wurden bereits verübt (Ermordung des bulgarischen Dissidenten Markov, 1978). Vor diesem Hintergrund stellt die Verwendung von Rizin als mögliche bioterroristische Waffe im Rahmen von Anschlägen auf kleinere bis mittlere Personengruppen kein unrealistisches Szenario dar, zumal bereits 2003 Hinweise auf Experimente zur Nutzung von Rizin im Umfeld einer islamistischen Gruppe in London gefunden wurden. Daher besteht der dringende Bedarf, schnelle, verlässliche und hochsensitive Detektionsmethoden zu etablieren, die nicht nur im stationären Laborbereich, sondern auch bei der Vor-Ort-Detektion angewendet werden können. Im vorliegenden Beitrag wird eine Übersicht über klassische immunologische Methoden für den Laborbereich gegeben (ELISA, Western Blot sowie Anreicherungsmethoden) und aktuelle Entwicklungen auf dem Gebiet der Vor-Ort- Detektion (elektrischer Biochip, Hand-Held-Testkits) vorgestellt.
sj-docx-10-hpq-10.1177_13591053211027626 – for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK
Creators: name: Hanson, Kristin
name: O’Dwyer, Emma
name: Chaudhuri, Sharmistha
name: Silva Souza, Luiz Gustavo
name: Vandrevala, Tushna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: sj-docx-10-hpq-10.1177_13591053211027626 for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK by Kristin Hanson, Emma O’Dwyer, Sharmistha Chaudhuri, Luiz Gustavo Silva Souza and Tushna Vandrevala in Journal of Health Psychology
sj-pdf-1-smm-10.1177_09622802211022385 - Supplemental material for Applications of simple and accessible methods for meta-analysis involving rare events: A simulation study
Creators: name: Hodkinson, Alexander
name: Kontopantelis, Evangelos
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-smm-10.1177_09622802211022385 for Applications of simple and accessible methods for meta-analysis involving rare events: A simulation study by Alexander Hodkinson and Evangelos Kontopantelis in Statistical Methods in Medical Research
Supplemental Material, sj-pdf-3-mns-10.1177_20592043211012396 - The Perception of Musical Expression in the Nineteenth Century: The Case of the Glorifying Hymnic*
Creators: name: Hentschel, Frank
name: Kreutz, Gunter
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 190406 Music Composition
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 190407 Music Performance
subject: 190409 Musicology and Ethnomusicology

description: Supplemental Material, sj-pdf-3-mns-10.1177_20592043211012396 for The Perception of Musical Expression in the Nineteenth Century: The Case of the Glorifying Hymnic* by Frank Hentschel and Gunter Kreutz in Music & Science
CMS upgrade and future plans
Creators: name: Hoepfner, Kerstin
name: CMS Collaboration
Publisher: name: RWTH Aachen University
Year: 2015
Subjects: subject: 530

description: 3rd International Conference on New Frontiers in Physics, ICNFP, Kolymbari, Greece, 28 Jul 2014 - 6 Aug 2014; Les Ulis : EDP Sciences, The European physical journal / Web of Conferences, 95, 03016, 10 S. (2015). doi:10.1051/epjconf/20159503016
description: Published by EDP Sciences, Les Ulis
Supplemental Material, sj-pdf-2-jps-10.1177_24755303211026023 - Identifying Novel Psoriatic Disease Drug Targets Using a Genetics-Based Priority Index Pipeline
Creators: name: Bui, Audrey
name: Liu, Jared
name: Hong, Julie
name: Hadeler, Edward
name: Mosca, Megan
name: Brownstone, Nicholas
name: Liao, Wilson
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental Material, sj-pdf-2-jps-10.1177_24755303211026023 for Identifying Novel Psoriatic Disease Drug Targets Using a Genetics-Based Priority Index Pipeline by Audrey Bui, Jared Liu, Julie Hong, Edward Hadeler, Megan Mosca, Nicholas Brownstone and Wilson Liao in Journal of Psoriasis and Psoriatic Arthritis
Recurrent Lorentzian Weyl spaces
Creators: name: Dikarev, Andrei
name: Galaev, Anton S.
name: Schneider, Eivind
Publisher: name: arXiv
Year: 2022
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We find the local form of all non-closed Lorentzian Weyl manifolds $(M,c,\nabla)$ with recurrent curvature tensor.If the dimension of the manifold is greater than 3, then the conformal structure is flat, and the recurrent Weyl structure is locally determined by a single function. Two local structures are equivalent if and only if the corresponding functions are related by a transformation from $\mathrm{SAff}_1(\mathbb{R}) \times \mathrm{PSL}_2(\mathbb{R}) \times \mathbb{Z}_2$. We find generators for the field of rational scalar differential invariants of this Lie group action. The global structure of the manifold $M$ may be described in terms of a foliation with a transversal projective structure. It is shown that all locally homogeneous structures are locally equivalent, and there is only one simply connected homogeneous non-closed recurrent Lorentzian Weyl manifold. Moreover, there are 5 classes of cohomogeneity-one spaces, and all other spaces are of cohomogeneity-two. If $\dim M=3$, the non-closed recurrent Lorentzian Weyl structures are locally determined by one function of two variables or two functions of one variables, depending on whether its holonomy algebra is 1- or 2-dimensional. In this case, two structures with the same holonomy algebra are locally equivalent if and only if they are related, respectively, by a transformation from an infinite-dimensional Lie pseudogroup or a 4-dimensional subgroup of $\mathrm{Aff}(\mathbb R^3)$. Again we provide generators for the field of rational differential invariants. We find a local expression for the locally homogeneous non-closed recurrent Lorentzian Weyl manifolds of dimension 3, and also of those of cohomogeneity one and two. In the end we give a local description of the non-closed recurrent Lorentzian Weyl manifolds that are also Einstein-Weyl. All of them are 3-dimensional and have a 2-dimensional holonomy algebra.
description: 32 pages; the final version
Supplemental Material, sj-pdf-6-jps-10.1177_24755303211026023 - Identifying Novel Psoriatic Disease Drug Targets Using a Genetics-Based Priority Index Pipeline
Creators: name: Bui, Audrey
name: Liu, Jared
name: Hong, Julie
name: Hadeler, Edward
name: Mosca, Megan
name: Brownstone, Nicholas
name: Liao, Wilson
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental Material, sj-pdf-6-jps-10.1177_24755303211026023 for Identifying Novel Psoriatic Disease Drug Targets Using a Genetics-Based Priority Index Pipeline by Audrey Bui, Jared Liu, Julie Hong, Edward Hadeler, Megan Mosca, Nicholas Brownstone and Wilson Liao in Journal of Psoriasis and Psoriatic Arthritis
Supplemental Material, sj-pdf-8-jps-10.1177_24755303211026023 - Identifying Novel Psoriatic Disease Drug Targets Using a Genetics-Based Priority Index Pipeline
Creators: name: Bui, Audrey
name: Liu, Jared
name: Hong, Julie
name: Hadeler, Edward
name: Mosca, Megan
name: Brownstone, Nicholas
name: Liao, Wilson
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental Material, sj-pdf-8-jps-10.1177_24755303211026023 for Identifying Novel Psoriatic Disease Drug Targets Using a Genetics-Based Priority Index Pipeline by Audrey Bui, Jared Liu, Julie Hong, Edward Hadeler, Megan Mosca, Nicholas Brownstone and Wilson Liao in Journal of Psoriasis and Psoriatic Arthritis
A Science Gateway for Molecular Simulations
Creators: name: Gesing, Sandra
name: Kacsuk, Peter
name: Kozlovsky, Miklos
name: Birkenheuer, Georg
name: Blunk, Dirk
name: Breuers, Sebastian
name: Brinkmann, Andre
name: Fels, Gregor
name: Grunzke, Richard
name: Herres-Pawlis, Sonja
name: Krüger, Jens
name: Packschies, Lars
name: Müller-Pfefferkorn, Ralf
name: Schäfer, Patrick
name: Steinke, Thomas
name: Fabri, Anna Szikszay
name: Warzecha, Klaus
name: Wewior, Martin
Publisher: name: RWTH Aachen University
Year: 2011

description: Book of abstracts / EGI User Forum 2011 held in conjunction with the EMI Technical Conference : 11–14 April 2011, Vilnius, Lithuania. Editors: Sara Coelho, Neasan O’Neill EGI User Forum 2011, Vilnius, Lithuania, 11 Apr 2011 - 14 Apr 2011; Amsterdam : EGI.eu, 94-94 (2011). doi:10.18154/RWTH-2015-04977
description: Published by EGI.eu, Amsterdam
Edge modes as dynamical frames: charges from post-selection in generally covariant theories
Creators: name: Carrozza, Sylvain
name: Eccles, Stefan
name: Hoehn, Philipp A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We develop a framework based on the covariant phase space formalism that identifies gravitational edge modes as dynamical reference frames. They enable the identification of the associated spacetime region and the imposition of boundary conditions in a gauge-invariant manner. While recent proposals considered the finite region in isolation and sought the maximal symmetry algebra compatible with that perspective, we regard it as a subregion embedded in a global spacetime and study the symmetries consistent with such an embedding. This clarifies that the frame, although appearing as "new" for the subregion, is built out of the field content of the complement. Given a global variational principle, this also permits us to invoke a systematic post-selection procedure, previously used in gauge theory [arXiv:2109.06184], to produce consistent dynamics for a subregion with timelike boundary. Requiring the subregion presymplectic structure to be conserved by the dynamics leads to an essentially unique prescription and unambiguous Hamiltonian charges. Unlike other proposals, this has the advantage that all spacetime diffeomorphisms acting on the subregion remain gauge and integrable, thus generating a first-class constraint algebra. By contrast, diffeomorphisms acting on the frame-dressed spacetime are physical, and those that are parallel to the boundary are integrable. Further restricting to ones preserving the boundary conditions yields an algebra of conserved charges. These record changes in the relation between the region and its complement as measured by frame reorientations. Finally, we explain how the boundary conditions and presymplectic structure can be encoded into boundary actions. While our formalism applies to any generally covariant theory, we illustrate it on general relativity, and conclude with a detailed comparison of our findings to earlier works. [abridged]
description: 54 + 10 pages, 5 figures, 2 tables. v2 includes minor modifications, predominantly improved exposition and comparison with different proposals in the literature
Empirical Fading Model and Bayesian Calibration for Multipath-Enhanced Device-Free Localization
Creators: name: Schmidhammer, Martin
name: Gentner, Christian
name: Walter, Michael
name: Sand, Stephan
name: Siebler, Benjamin
name: Fiebig, Uwe-Carsten
Publisher: name: arXiv
Year: 2022
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The performance of multipath-enhanced device-free localization severely depends on the information about the propagation paths within the network. While known for the line-of-sight, the propagation paths have yet to be determined for multipath components. This work provides a novel Bayesian calibration approach for determining the propagation paths by estimating reflection points. Therefore, first a statistical fading model is presented, that describes user-induced changes in the received signal of multipath components. The model is derived and validated empirically using an extensive set of wideband and ultra-wideband measurement data. Second, the Bayesian approach is presented, which, based on the derived empirical fading model, relates measured changes in the power of a multipath component to the location of the reflection point. Exploiting the geometric properties of multipath components caused by single-bounce reflections, the solution space of possible locations of reflection points is constrained to the delay ellipse. Thus, a one-dimensional elliptic estimation problem can be formulated, which is solved using a point mass filter. The applicability of the proposed approach is demonstrated and evaluated based on measurement data. Independent of the underlying measurement system, the Bayesian calibration approach is shown to robustly estimate the locations of the reflection points in different environments.
description: 14 pages, 9 figures
Age, puberty, body dissatisfaction, and physical activity decline in adolescents. Results of the German Health Interview and Examination Survey (KiGGS)
Creators: name: Finne, Emily
name: Bucksch, Jens
name: Lampert, Thomas
name: Kolip, Petra
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2011
Subjects: subject: adolescents
subject: physical activity
subject: sexual maturation
subject: pubertal timing
subject: body dissatisfaction
subject: 610 Medizin

description: Background: Physical activity (PA) shows a marked decline during adolescence. Some studies have pointed to pubertal status or timing as possible PA determinants in this age group. Furthermore, it was supposed that the impact of pubertal changes on PA might be mediated by psychological variables like body dissatisfaction (BDS). Methods: The 11- to 17-year-old subsample of the German Health Interview and Examination Survey (KiGGS) was used (n = 6 813; 51.3% male, response rate = 66.6%). Through sex-specific sequential multinomial logistic regressions we analysed the univariate and independent associations of chronological age, absolute pubertal status, relative pubertal timing, and BDS with the frequency of PA. Results: Chronological age showed a significantly negative association with PA in both sexes, independent of puberty. The odds of inactivity in contrast to nearly daily PA increased about 70% in boys and 35% in girls for each year of age, respectively. Adjusted for age and other possible confounders, inactivity was significantly less likely for boys in late pubertal stages (OR = 0.27, 95% CI = 0.09-0.78). The risk of inactivity was more than doubled in boys maturing earlier than peers in terms of relative pubertal timing (OR = 2.20, 95% CI = 1.36-3.56). No clear significant puberty effects were found in girls, but the inactivity was more likely for those with irregular menstruation (OR = 1.71, 95% CI = 1.06-2.75). BDS also contributed to the prediction of PA in both sexes. It partially mediated puberty effects in boys but not in girls. Conclusions: Overall, chronological age was a far more important predictor of PA in German adolescents than absolute pubertal status or relative pubertal timing. Further possible explanatory variables like sociocultural influences, social support or increasing time requirements for education should be analysed in conjunction with chronological age in future studies.
Detection of Norovirus genogroup I and II by multiplex real-time RT- PCR using a 3'-minor groove binder-DNA probe
Creators: name: Hoehne, Marina
name: Schreier, Eckart
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2006
Subjects: subject: Animals
subject: Humans
subject: RNA
subject: Viral/analysis
subject: Sensitivity and Specificity
subject: Caliciviridae Infections/diagnosis
subject: DNA Primers
subject: DNA Probes
subject: Gastroenteritis/diagnosis
subject: Norovirus/classification
subject: Norovirus/genetics
subject: Norovirus/isolation & purification
subject: Reverse Transcriptase Polymerase Chain Reaction/methods
subject: 610 Medizin

description: Background: Due to an increasing number of norovirus infections in the last years rapid, specific, and sensitive diagnostic tools are needed. Reverse transcriptase-polymerase chain reactions (RT-PCR) have become the methods of choice. To minimize the working time and the risk of carryover contamination during the multi-step procedure of PCR the multiplex real-time RT-PCR for the simultaneous detection of genogroup I (GI) and II (GII) offers advantages for the handling of large amounts of clinical specimens. Methods: We have developed and evaluated a multiplex one-tube RT-PCR using a combination of optimized GI and GII specific primers located in the junction between ORF1 and ORF2 of the norovirus genome. For the detection of GI samples, a 3'-minor groove binder-DNA probe (GI-MGB-probe) were designed and used for the multiplex real-time PCR. Results: Comparable results to those of our in-house nested PCR and monoplex real-time-PCR were only obtained using the GI specific MGB-probe. The MGB-probe forms extremely stable duplexes with single-stranded DNA targets, which enabled us to design a shorter probe (length 15 nucleotides) hybridizing to a more conserved part of the GI sequences. 97% of 100 previously norovirus positive specimens (tested by nested PCR and/or monoplex real-time PCR) were detected by the multiplex real-time PCR. A broad dynamic range from 2 x 10(1) to 2 x 10(7) genomic equivalents per assay using plasmid DNA standards for GI and GII were obtained and viral loads between 2.5 x 10(2) and 2 x 10(12) copies per ml stool suspension were detected. Conclusion: The one-tube multiplex RT real-time PCR using a minor groove binder-DNA probe for GI is a fast, specific, sensitive and cost-effective tool for the detection of norovirus infections in both mass outbreaks and sporadic cases and may have also applications in food and environmental testing.
Underreporting of Human Alveolar Echinococcosis in Germany.
Creators: name: Jorgensen, Pernille
name: Heiden, Matthias An Der
name: Kern, Petra
name: Schöneberg, Irene
name: Krause, Gérard
name: Alpers, Katharina
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2008
Subjects: subject: Adolescent
subject: Humans
subject: Female
subject: Germany
subject: Male
subject: Middle Aged
subject: Population Surveillance/methods
subject: Incidence
subject: Sensitivity and Specificity
subject: Adult
subject: Aged
subject: Disease Notification/statistics & numerical data
subject: Echinococcosis
subject: Hepatic/epidemiology
subject: Hepatic/parasitology
subject: Epidemiologic Methods
subject: Aged 80 and over
subject: 610 Medizin

description: We estimated the total number of human alveolar echinococcosis cases in Germany from 2003 through 2005 using the multiple source capture-recapture method. We found a 3-fold higher incidence of the disease than that shown by national surveillance data. We propose a revision of the reporting system to increase case ascertainment.
Leptospirosis in urban wild boars, Berlin, Germany.
Creators: name: Jansen, Andreas
name: Luge, Enno
name: Guerra, Beatriz
name: Wittschen, Petra
name: Gruber, Achim D.
name: Loddenkemper, Christoph
name: Schneider, Thomas
name: Lierz, Michael
name: Ehlert, Derk
name: Appel, Bernd
name: Stark, Klaus
name: Nöckler, Karsten
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2007
Subjects: subject: Animals
subject: Bacterial
subject: Male
subject: Antibodies
subject: Seroepidemiologic Studies
subject: Berlin/epidemiology
subject: Disease Reservoirs/microbiology
subject: Disease Reservoirs/v Humans
subject: Leptospirosis/epidemiology
subject: Leptospirosis/veterinary
subject: Serologic Tests
subject: Sus scrofa/parasitology
subject: Swine Diseases/epidemiology
subject: 610 Medizin

description: We found antibodies to leptospires in 25 (18%) of 141 wild boars from Berlin (95% confidence interval 12-25). Seropositivity was associated with chronic interstitial nephritis (odds ratio 10.5; p=0.01), and leptospires were detected in kidney tissues. Wild boars represent a potential source for human leptospirosis in urban environments.
Rational partition models under iterative proportional scaling
Creators: name: Coons, Jane Ivy
name: Langer, Carlotta
name: Ruddy, Michael
Publisher: name: arXiv
Year: 2022
Subjects: subject: Algebraic Geometry (math.AG)
subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: 05C90, 62A09, 62B10, 62R01

description: In this work we investigate partition models, the subset of log-linear models for which one can perform the iterative proportional scaling (IPS) algorithm to numerically compute the maximum likelihood estimate (MLE). Partition models include families of models such as hierarchical models and balanced, stratified staged trees. We define a sufficient condition, called the Generalized Running Intersection Property (GRIP), on the matrix representation of a partition model under which IPS algorithm produces the exact MLE in one cycle. Additionally we connect the GRIP to the toric fiber product and to previous results for hierarchical models and balanced, stratified staged trees. This leads to a characterization of balanced, stratified staged trees in terms of the GRIP.
description: 41 pages, 8 figures
sj-docx-2-taj-10.1177_20406223211026993 – Supplemental material for Sitagliptin on carotid intima-media thickness in type 2 diabetes and hyperuricemia patients: a subgroup analysis of the PROLOGUE study
Creators: name: Zhao, Yipin
name: Wang, Huawei
name: Ke, Dazhi
name: Deng, Wei
name: Ji, Yingying
name: Yang, Jiaojiao
name: Lin, Zebin
name: Li, Guoxing
name: Xiao, Li
name: Tang, Jianmin
name: Chen, Qingwei
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Respiratory Diseases

description: Supplemental material, sj-docx-2-taj-10.1177_20406223211026993 for Sitagliptin on carotid intima-media thickness in type 2 diabetes and hyperuricemia patients: a subgroup analysis of the PROLOGUE study by Yipin Zhao, Huawei Wang, Dazhi Ke, Wei Deng, Yingying Ji, Jiaojiao Yang, Zebin Lin, Guoxing Li, Li Xiao, Jianmin Tang and Qingwei Chen in Therapeutic Advances in Chronic Disease
Additional file 1 of Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK helicopter emergency medical service– a retrospective observational review of practice
Creators: name: Butterfield, Emma D.
name: Price, James
name: Bonsano, Marco
name: Lachowycz, Kate
name: Starr, Zachary
name: Edmunds, Christopher
name: Barratt, Jon
name: Major, Rob
name: Rees, Paul
name: Barnard, Ed B. G.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Wie groß sind die Differenzen zwischen den europäischen Pandemieplänen, sind sie relevant und woher stammen sie?
Creators: name: Haas, Walter
name: Straetemans, Masja
name: Pfaff, Günter
name: Nicoll, A.
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2009
Subjects: subject: Influenza
subject: Pandemievorbereitung
subject: Grenzüberschreitende Zusammenarbeit
subject: Krisenmanagement
subject: influenza
subject: andemic preparedness
subject: cross-border interoperability
subject: crisis management
subject: 610 Medizin

description: Die Koordination der Influenzapandemieplanung innerhalb Europas ist für Deutschland von besonderer Bedeutung, da 10 von 16 Bundesländern an Nachbarstaaten angrenzen. Hierbei müssen nicht nur sprachliche Barrieren überwunden werden. Die Schaffung eines europäischen Frühwarnsystems durch Vernetzung der Surveillance-Strukturen und eines Kommunikationsnetzwerkes sind erste wichtige Schritte. Verschiedene Abstimmungsinstrumente wurden entwickelt, und das neu geschaffene Europäische Zentrum für die Prävention und die Kontrolle von Krankheiten (ECDC) übernimmt eine wichtige Rolle bei der Koordination und Erfassung der Planungsfortschritte. Die Umsetzungsgeschwindigkeiten der einzelnen Mitgliedstaaten bezüglich der Vorbereitung auf eine Influenzapandemie und die Schwerpunkte ihrer Planungen variieren. Die hier vorliegende Analyse aus dem europäischen, nationalen und lokalen Blickwinkel soll die Chancen und Risiken dieser Diversität für die Bewältigung einer Pandemie aufzeigen. Regionale Initiativen zur grenzüberschreitenden Umsetzung der Planungen und der Maßnahmen im Krisen management spielen eine besondere Rolle bei der Vorbereitung auf eine Influenzapandemie.
description: The coordination of influenza pandemic preparedness planning within Europe is especially important for Germany with 10 out of 16 Länder (regions) bordering neighbouring countries. The language barrier presents only one of the challenges to overcome. Creating a European early warning system by linking national surveillance structures and the development of a communication network are important initial achievements. Several instruments have been designed and the European Centre for Disease Prevention and Control has already played a major role in the coordination of this process. It has also led the assessment of preparedness and planning by Member States. The speed of the European Member States in preparing for and the foci they have chosen when dealing with an influenza outbreak are heterogeneous. The simultaneous analysis presented here from European, national and regional points of view aims to identify both opportunities and risks of this diversity in Europe for coping with a new pandemic. Regional and local initiatives for cross-border measures and crisis management will play a central role in achieving successful influenza pandemic preparedness in Europe.
Additional file 2 of Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK helicopter emergency medical service– a retrospective observational review of practice
Creators: name: Butterfield, Emma D.
name: Price, James
name: Bonsano, Marco
name: Lachowycz, Kate
name: Starr, Zachary
name: Edmunds, Christopher
name: Barratt, Jon
name: Major, Rob
name: Rees, Paul
name: Barnard, Ed B. G.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
Mackey-type identity for invariant functions on Lie algebras of finite unitary groups and an application
Creators: name: Cuenca, Cesar
name: Olshanski, Grigori
Publisher: name: arXiv
Year: 2022
Subjects: subject: Representation Theory (math.RT)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: The Mackey-type identity mentioned in the title relates the operations of parabolic induction and restriction for invariant functions on the Lie algebras of the finite unitary groups $U(N, q^2)$. This result is applied to constructing positive harmonic functions on a new branching graph with a negative Hall-Littlewood parameter, as introduced in the authors' paper [Adv. Math. vol. 395 (2022), 108087; arXiv:2102.01947].This in turn implies the existence of an infinite-parameter family of invariant measures for the coadjoint action of an infinite-dimensional analogue of the groups $U(N, q^2)$.
description: 20 pp; Version 2: minor changes and corrections
Additional file 1 of Evaluation of the Autof ms1000 mass spectrometry for rapid clinical identification of filamentous fungi
Creators: name: Ao, Keping
name: Li, Xiaohan
name: Zhang, Weili
name: Chen, Zhixing
name: Liu, Ya
name: Shu, Ling
name: Xiao, Yuling
name: Wu, Siying
name: Xie, Yi
name: Kang, Mei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Table S1? Autof ms1000 mass spectrometry identification results by Routine pretreatment.
Supplemental Material, sj-docx-1-slg-10.1177_0160323X211025101 - Pennsylvania in 2018: How Redistricting Does and Doesn’t Make a Difference
Creators: name: Hicks, William D.
name: McKee, Seth C.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 160509 Public Administration

description: Supplemental Material, sj-docx-1-slg-10.1177_0160323X211025101 for Pennsylvania in 2018: How Redistricting Does and Doesn’t Make a Difference by William D. Hicks and Seth C. McKee in State and Local Government Review
sj-docx-1-pmj-10.1177_02692163211026518 – Supplemental material for Increased number of deaths within 24 h of admission during a period of social restriction related to the COVID-19 pandemic: A retrospective service evaluation in a metropolitan palliative care unit
Creators: name: Everitt, Rachel
name: Robinson, Neil
name: Marco, David
name: Weil, Jennifer
name: Bryan, Tamsin
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-pmj-10.1177_02692163211026518 for Increased number of deaths within 24 h of admission during a period of social restriction related to the COVID-19 pandemic: A retrospective service evaluation in a metropolitan palliative care unit by Rachel Everitt, Neil Robinson, David Marco, Jennifer Weil and Tamsin Bryan in Palliative Medicine
Additional file 3 of Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK helicopter emergency medical service– a retrospective observational review of practice
Creators: name: Butterfield, Emma D.
name: Price, James
name: Bonsano, Marco
name: Lachowycz, Kate
name: Starr, Zachary
name: Edmunds, Christopher
name: Barratt, Jon
name: Major, Rob
name: Rees, Paul
name: Barnard, Ed B. G.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 3
sj-docx-16-hpq-10.1177_13591053211027626 – for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK
Creators: name: Hanson, Kristin
name: O’Dwyer, Emma
name: Chaudhuri, Sharmistha
name: Silva Souza, Luiz Gustavo
name: Vandrevala, Tushna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: sj-docx-16-hpq-10.1177_13591053211027626 for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK by Kristin Hanson, Emma O’Dwyer, Sharmistha Chaudhuri, Luiz Gustavo Silva Souza and Tushna Vandrevala in Journal of Health Psychology
sj-docx-4-hpq-10.1177_13591053211027626 – for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK
Creators: name: Hanson, Kristin
name: O’Dwyer, Emma
name: Chaudhuri, Sharmistha
name: Silva Souza, Luiz Gustavo
name: Vandrevala, Tushna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: sj-docx-4-hpq-10.1177_13591053211027626 for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK by Kristin Hanson, Emma O’Dwyer, Sharmistha Chaudhuri, Luiz Gustavo Silva Souza and Tushna Vandrevala in Journal of Health Psychology
Intrinsic tension in the supernova sector of the local Hubble constant measurement and its implications
Creators: name: Wojtak, Radosław
name: Hjorth, Jens
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We reanalyse observations of type Ia supernovae (SNe) and Cepheids used in the local determination of the Hubble constant and find strong evidence that SN standardisation in the calibration sample (galaxies with observed Cepheids) require a steeper slope of the colour correction than in the cosmological sample (galaxies in the Hubble flow). The colour correction in the calibration sample is consistent with being entirely due to an extinction correction due to dust with properties similar to that of the Milky Way (R_B~4.6+/-0.4) and there is no evidence for intrinsic scatter in the SN peak magnitudes. An immediate consequence of this finding is that the local measurement of the Hubble constant becomes dependent on the choice of SN reference colour, i.e., the colour of an unreddened SN. Specifically, the Hubble constant inferred from the same observations decreases gradually with the reference colour assumed in the SN standardisation. We recover the Hubble constant measured by SH0ES for the standard choice of reference colour (SALT2 colour parameter c=0) while for a reference colour which coincides with the blue end of the observed SN colour distribution (c~-0.13), the Hubble constant from Planck observations of the CMB (assuming a flat LCDM cosmological model) is recovered. These results are intriguing in that they may provide an avenue for resolving the Hubble tension. However, since there is no obvious physical basis for the differences in colour corrections in the two SN samples, the origin of these require further investigations.
description: 12 pages, 4 figures, 3 tables; accepted for publication in MNRAS