cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Closure of the single fluid magnetohydrodynamic equations in presence of electron cyclotron current drive
Creators: name: Westerhof, Egbert
name: Pratt, Jane
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In the presence of electron cyclotron current drive (ECCD), the Ohm's law of single fluid magnetohydrodynamics (MHD) is modified as ${\bf E} + {\bf v} \times {\bf B} = η( {\bf J} - {\bf J}_{\rm EC} )$. This paper presents a new closure relation for the EC driven current density appearing in this modified Ohm's law. The new relation faithfully represents the nonlocal character of the EC driven current and its main origin in the Fisch-Boozer effect. The closure relation is validated on both an analytical solution of an approximated Fokker-Planck equation as well as on full bounce-averaged, quasi-linear Fokker-Planck code simulations of ECCD inside rotating magnetic islands. The new model contains the model put forward by Giruzzi et al., Nucl. Fusion 39 (1999) 107, in one of its limits.
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder
Creators: name: Akterin, S
name: Bergen, S E
name: Scolnick, E M
name: Handsaker, R E
name: Hultman, C M
name: Moran, J L
name: Sullivan, P F
name: McCarroll, S
name: Landen, M
name: Magnusson, P K E
name: Purcell, S M
name: Ösby, U
name: Chambert, K D
name: Lichtenstein, P
name: Backlund, L
name: Ruderfer, D M
name: Lee, P H
name: Ripke, S
name: O'Dushlaine, C T
name: Sklar, P
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable psychiatric disorders with overlapping susceptibility loci and symptomatology. We conducted a genome-wide association study (GWAS) of these disorders in a large Swedish sample. We report a new and independent case–control analysis of 1507 SCZ cases, 836 BD cases and 2093 controls. No single-nucleotide polymorphisms (SNPs) achieved significance in these new samples; however, combining new and previously reported SCZ samples (2111 SCZ and 2535 controls) revealed a genome-wide significant association in the major histocompatibility complex (MHC) region (rs886424, P = 4.54 × 10−8). Imputation using multiple reference panels and meta-analysis with the Psychiatric Genomics Consortium SCZ results underscored the broad, significant association in the MHC region in the full SCZ sample. We evaluated the role of copy number variants (CNVs) in these subjects. As in prior reports, deletions were enriched in SCZ, but not BD cases compared with controls. Singleton deletions were more frequent in both case groups compared with controls (SCZ: P = 0.003, BD: P = 0.013), whereas the largest CNVs (>500 kb) were significantly enriched only in SCZ cases (P = 0.0035). Two CNVs with previously reported SCZ associations were also overrepresented in this SCZ sample: 16p11.2 duplications (P = 0.0035) and 22q11 deletions (P = 0.03). These results reinforce prior reports of significant MHC and CNV associations in SCZ, but not BD.
Inconsistency in the experimentally derived relationship between epilithon abundance and the micro-distribution of Agapetus monticolus (Trichoptera)
Creators: name: Gawne, Benjamin
Publisher: name: La Trobe
Year: 2023

description: Murray-Darling Freshwater Research Centre

MDFRC item.

Studies of the micro-distribution of herbivorous lotic macroinvertebrates have tended to rely on short-term experiments. While these experiments have provided information on the factors that determine the distributions of herbivorous invertebrates, they ignore the complexity of the epilithon as a food source, any interaction between physical and biological factors and the possibility that the factors that determine an invertebrate species' distribution may vary through time. Five colonization experiments were performed in an Australian upland stream to determine the role of epilithon abundance in the distribution of an abundant invertebrate (Agapetus monticolus: Trichoptera). Artificial cobbles with different types and amounts of epilithon were placed in the Taggerty River at two sites and the response of A. monticolus recorded. The experiments revealed that, although A. monticolus expressed a preference for patches of epilithon with abundant periphyton, the response varied among experiments performed at different times and was always secondary to the flow preferences of A. monticolus. Studies that fail to acknowledge the presence of temporal variation in the response of animals to their environment run the risk that they will over- or underestimate the importance of particular factors because of the timing of their experiment.
Filamentary Star Formation in NGC 1275
Creators: name: Canning, R. E. A
name: Ryon, J. E.
name: Gallagher, J. S.
name: Kotulla, R.
name: O'Connell, R. W.
name: Fabian, A. C.
name: Johnstone, R. M.
name: Conselice, C. J.
name: Hicks, A.
name: Rosario, D.
name: Wyse, R. F. G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We examine the star formation in the outer halo of NGC~1275, the central galaxy in the Perseus cluster (Abell 426), using far ultraviolet and optical images obtained with the Hubble Space Telescope. We have identified a population of very young, compact star clusters with typical ages of a few Myr. The star clusters are organised on multiple-kiloparsec scales. Many of these star clusters are associated with "streaks" of young stars, the combination of which has a cometary appearance. We perform photometry on the star clusters and diffuse stellar streaks, and fit their spectral energy distributions to obtain ages and masses. These young stellar populations appear to be normal in terms of their masses, luminosities and cluster formation efficiency; <10% of the young stellar mass is located in star clusters. Our data suggest star formation is associated with the evolution of some of the giant gas filaments in NGC~1275 that become gravitationally unstable on reaching and possibly stalling in the outer galaxy. The stellar streaks then could represent stars moving on ballistic orbits in the potential well of the galaxy cluster. We propose a model where star-forming filaments, switched on ~50~Myr ago and are currently feeding the growth of the NGC~1275 stellar halo at a rate of ~2-3 solar masses per year. This type of process may also build stellar halos and form isolated star clusters in the outskirts of youthful galaxies.
description: 15 pages, 10 figures, accepted for publication in MNRAS
Spinning (A)dS Black Holes with Slow-Rotation Approximation in Dynamical Chern-Simons Modified Gravity
Creators: name: Nashed, G. G. L.
name: Capozziello, S.
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: One of the most crucial areas of gravity research, after the direct observation of gravitational waves, is the possible modification of General Relativity at ultraviolet and infrared scales. In particular, the possibility of parity violation should be considered in strong field regime. The Chern-Simons gravity takes into account parity violation in strong gravity regime. For all conformally flat spacetimes and spacetimes with a maximally symmetric two-dimensional subspace, Chern-Simons gravity is identical to General Relativity. Specifically, the Anti-de Sitter (A)dS-Kerr/Kerr black hole is not a solution for Chern-Simons gravity. The slow-rotating BH and the quadratic order in spin solutions are some of the known solutions to quadratic order in spin and they are rotating solutions in the frame of dynamical Chern-Simons gravity. In the present study, for the (A)dS slow-rotating situation (correct to the first order in spin), we derive the linear perturbation equations controlling the metric and the dynamical Chern-Simons field equation corrected to the linear order in spin and to the second order in the Chern-Simons coupling parameter. We show that the black hole of the (A)dS-Kerr solution is stronger (i.e. more compact and energetic) than the Kerr black hole solution and the reason for this feature comes form contributions at Planck scales. Moreover, we calculate the thermodynamical quantities related to this black hole. Finally, we calculate the geodesic equation and derive the effective potential of the black hole.
description: 15 pages 3 figures, will appear in Phys. Rev D
Genome-wide association study of major depressive disorder: new results, meta-analysis and lessons learned
Creators: name: Hottenga, J J
name: Pergadia, M L
name: Medland, S E
name: Sullivan, P F
name: Nyholt, D R
name: Hickie, I B
name: Ripke, S
name: MacIntyre, D J
name: Macgregor, S
name: Gordon, S D
name: Heath, A C
name: Martin, N G
name: McGhee, K A
name: Maclean, A W
name: Penninx, B W J H
name: Madden, P A F
name: Smit, J H
name: Middeldorp, C M
name: Boomsma, D I
name: de Geus, E J C
name: Liu, J Z
name: Lewis, C M
name: Blackwood, D H R
name: Willemsen, G
name: Wray, N R
name: Henders, A K
name: McGuffin, P
name: Statham, D J
name: Montgomery, G W
name: van den Oord, E J C G
name: McEvoy, B P
name: Byrne, E M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed single-nucleotide polymorphisms (SNPs)). No SNPs achieved genome-wide significance either in the MDD2000+ study, or in meta-analysis with two other studies totaling 5763 cases and 6901 controls. These results imply that common variants of intermediate or large effect do not have main effects in the genetic architecture of MDD. Suggestive but notable results were (a) gene-based tests suggesting roles for adenylate cyclase 3 (ADCY3, 2p23.3) and galanin (GAL, 11q13.3); published functional evidence relates both of these to MDD and serotonergic signaling; (b) support for the bipolar disorder risk variant SNP rs1006737 in CACNA1C (P=0.020, odds ratio=1.10); and (c) lack of support for rs2251219, a SNP identified in a meta-analysis of affective disorder studies (P=0.51). We estimate that sample sizes 1.8- to 2.4-fold greater are needed for association studies of MDD compared with those for schizophrenia to detect variants that explain the same proportion of total variance in liability. Larger study cohorts characterized for genetic and environmental risk factors accumulated prospectively are likely to be needed to dissect more fully the etiology of MDD.
Meta-analysis of genome-wide association studies for personality
Creators: name: Ciullo, M
name: Amin, N
name: Willemsen, G
name: Sullivan, P
name: Sanna, S
name: de Geus, E J C
name: Terracciano, A
name: Krueger, R F
name: Hottenga, J-J
name: Nutile, T
name: Allik, J
name: Distel, M A
name: Uda, M
name: Lin, P
name: Konte, B
name: Derringer, J
name: Spinhoven, P
name: Pergadia, M L
name: de Moor, M H M
name: Hartman, C A
name: Realo, A
name: Esko, T
name: Giegling, I
name: Grucza, R
name: Heath, A C
name: Rujescu, D
name: Toshiko, T
name: Madden, P A F
name: Penninx, B W J H
name: Widen, E
name: Agrawal, A
name: Costa, P T
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Personality can be thought of as a set of characteristics that influence people’s thoughts, feelings, and behaviour across a variety of settings. Variation in personality is predictive of many outcomes in life, including mental health. Here we report on a meta-analysis of genome-wide association (GWA) data for personality in ten discovery samples (17 375 adults) and five in-silico replication samples (3 294 adults). All participants were of European ancestry. Personality scores for Neuroticism, Extraversion, Openness to Experience, Agreeableness, and Conscientiousness were based on the NEO Five-Factor Inventory. Genotype data were available of ~2.4M Single Nucleotide Polymorphisms (SNPs; directly typed and imputed using HAPMAP data). In the discovery samples, classical association analyses were performed under an additive model followed by meta-analysis using the weighted inverse variance method. Results showed genome-wide significance for Openness to Experience near the RASA1 gene on 5q14.3 (rs1477268 and rs2032794, P = 2.8 × 10−8 and 3.1 × 10−8) and for Conscientiousness in the brain-expressed KATNAL2 gene on 18q21.1 (rs2576037, P = 4.9 × 10−8). We further conducted a gene-based test that confirmed the association of KATNAL2 to Conscientiousness. In-silico replication did not, however, show significant associations of the top SNPs with Openness and Conscientiousness, although the direction of effect of the KATNAL2 SNP on Conscientiousness was consistent in all replication samples. Larger scale GWA studies and alternative approaches are required for confirmation of KATNAL2 as a novel gene affecting Conscientiousness.
Περιβαλλοντική διαχείριση λιμένων - Διερεύνηση πρακτικών και εφαρμογής
Creators: name: Γιαννούλης, Γεώργιος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2022
Subjects: subject: Περιβαλλοντική διαχείριση λιμένων
subject: Διερεύνηση πρακτικών και εφαρμογής
subject: Ρύπανση αέρα
subject: Ρύπανση θάλασσας
subject: Κατηγορίες ρύπων
subject: Διαχειριστικές πρακτικές
subject: Ευκολίες υποδοχής
subject: Παρακολούθηση περιβαλλοντικών παραμέτρων
subject: Monitoring

description: Η παρούσα διπλωματική εργασία εστιάζει στη περιβαλλοντική διαχείριση των λιμένων μέσω του θεσμικού πλαισίου προστασίας του περιβάλλοντος που επιβάλλεται στη λειτουργία τους. Καθώς και στη κατηγοριοποίηση των ρύπων και τους τρόπους παρακολούθησης και διαχείρισης τους. Για την καλύτερη ανάδειξης τους, εξετάζεται ως παράδειγμα ο Οργανισμός λιμένος Πειραιώς.
Accurate Analytic Mass-Scale Relations for Dark Matter Haloes of all Masses and Redshifts
Creators: name: Salvador-Solé, Eduard
name: Manrique, Alberto
name: Canales, David
name: Botella, Ignacio
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: CUSP is a powerful formalism that recovers, from first principles and with no free parameter, all the macroscopic properties of dark matter haloes found in cosmological N-body simulations and unveils the origin of their characteristic features. Since it is not restricted by the limitations of simulations, it covers the whole mass and redshift ranges. In the present Paper we use CUSP to calculate the mass-scale relations holding for halo density profiles fitted to the usual NFW and Einasto functions in the most relevant cosmologies and for the most usual mass definitions. We clarify the origin of these relations and provide accurate analytic expressions holding for all masses and redshifts. The performance of those expressions is compared to that of previous models and to the mass-concentration relation spanning more than 20 orders of magnitude in mass at $z=0$ obtained in recent simulations of a 100 GeV WIMP universe.
description: 16 pages, 14 figures, accepted for publication in MNRAS
Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
Creators: name: Winkler, Rene
name: Mägdefrau, Ann-Sophie
name: Piskor, Eva-Maria
name: Kleemann, Markus
name: Beyer, Mandy
name: Linke, Kevin
name: Hansen, Lisa
name: Schaffer, Anna-Maria
name: Hoffmann, Marina E.
name: Heyd, Florian
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: B-cell lymphoma
subject: Oncogenes
subject: MYC interaction network
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Overexpression of MYC is a genuine cancer driver in lymphomas and related to poor prognosis. However, therapeutic targeting of the transcription factor MYC remains challenging. Here, we show that inhibition of the histone deacetylase 6 (HDAC6) using the HDAC6 inhibitor Marbostat-100 (M-100) reduces oncogenic MYC levels and prevents lymphomagenesis in a mouse model of MYC-induced aggressive B-cell lymphoma. M-100 specifically alters protein-protein interactions by switching the acetylation state of HDAC6 substrates, such as tubulin. Tubulin facilitates nuclear import of MYC, and MYC-dependent B-cell lymphoma cells rely on continuous import of MYC due to its high turn-over. Acetylation of tubulin impairs this mechanism and enables proteasomal degradation of MYC. M-100 targets almost exclusively B-cell lymphoma cells with high levels of MYC whereas non-tumor cells are not affected. M-100 induces massive apoptosis in human and murine MYC-overexpressing B-cell lymphoma cells. We identified the heat-shock protein DNAJA3 as an interactor of tubulin in an acetylation-dependent manner and overexpression of DNAJA3 resulted in a pronounced degradation of MYC. We propose a mechanism by which DNAJA3 associates with hyperacetylated tubulin in the cytoplasm to control MYC turnover. Taken together, our data demonstrate a beneficial role of HDAC6 inhibition in MYC-dependent B-cell lymphoma.
Methane oxidation in sediments of a floodplain wetland in south-eastern Australia
Creators: name: Boon, P. I
name: Lee, K
Publisher: name: La Trobe
Year: 2023

description: La Trobe University Faculty of Science, Technology and Engineering Murray Darling Freshwater Research Centre

MDFRC item.

Potential rates of in vitro methane oxidation in sediments from a floodplain wetland in south-eastern Australia ranged between 0·05 and 0·45 μmol cm−3 h−1. These rates were at least an order of magnitude greater than were potential rates of in vitro methanogenesis, indicating that methanotrophic bacteria could intercept most of the methane produced in the sediments before it was lost to the atmosphere. This finding has implications for environmental management strategies designed to limit methane emissions from natural wetlands, and for fundamental studies of carbon cycling in natural freshwater environments, where methane emissions have been used as an indicator of rates of anaerobic decay of plant detritus. Methane oxidation was an obligately aerobic process, and added sulphate or nitrate could not replace oxygen as a suitable oxidant. Ammonium had little effect on methane oxidation, but allythiourea was strongly inhibitory.
Fermion field as inflaton, dark energy and dark matter
Creators: name: Grams, Guilherme
name: de Souza, Rudinei C.
name: Kremer, Gilberto M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The search for constituents that can explain the periods of accelerating expansion of the Universe is a fundamental topic in cosmology. In this context, we investigate how fermionic fields minimally and non-minimally coupled with the gravitational field may be responsible for accelerated regimes during the evolution of the Universe. The forms of the potential and coupling of the model are determined through the technique of the Noether symmetry for two cases. The first case comprises a Universe filled only with the fermion field. Cosmological solutions are straightforwardly obtained for this case and an exponential inflation mediated by the fermion field is possible with a non-minimal coupling. The second case takes account of the contributions of radiation and baryonic matter in the presence of the fermion field. In this case the fermion field plays the role of dark energy and dark matter, and when a non-minimal coupling is allowed, it mediates a power-law inflation.
description: 17 pages, 3 figures. To appear in Classical and Quantum Gravity
title: Οι συγκρούσεις στο σχολικό πλαίσιο με τη γονεϊκή εμπλοκή και η στάση της διεύθυνσης της σχολικής μονάδας
title: Conflicts in the school community due to parental involvement and the attitude of the school administrator
titleType: AlternativeTitle
Creators: name: Καδιανάκη, Γεωργία
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2023
Subjects: subject: Σύγκρουση
subject: Γονεϊκή εμπλοκή
subject: Στρατηγικές διαχείρισης

description: Αντικείμενο της παρούσας διπλωματικής εργασίας είναι οι συγκρούσεις στο σχολικό πλαίσιο, η γονεϊκη εμπλοκή και η στάση του διευθυντή της σχολικής μονάδας. Η διερεύνηση του θέματος γίνεται μέσα από βιβλιογραφική ανασκόπηση επιστημονικών άρθρων και βιβλίων που έχουν δημοσιευτεί για τα αντικείμενα της μελέτης, καθώς και μέσα από την ανάλυση των αποτελεσμάτων σχετικών ερευνών. Αρχικά, παρουσιάζονται ο ορισμός και τα χαρακτηριστικά της σύγκρουσης και της γονεϊκής εμπλοκής, των δύο βασικών εννοιών πάνω στις οποίες στηρίζεται η εργασία. Στη συνέχεια, περιγράφονται λεπτομερώς οι κατηγορίες αυτών αλλά και η συσχέτισή τους στο σχολικό πλαίσιο. Σημαντικό μέρος της εργασίας καταλαμβάνουν οι στρατηγικές διαχείρισης με τις οποίες ο/η διευθυντής,-ντρια στέκεται απέναντι στις συγκρούσεις και τη γονεϊκή εμπλοκή στο σχολείο. Επιπρόσθετα, αναλύεται και περιγράφεται η σχέση του ελληνικού εκπαιδευτικού συστήματος με την οικογένεια, ενώ, τέλος, οι συγκρούσεις μεταξύ των δύο και η διαχείρισή τους από τον ηγέτη της σχολικής μονάδας. Για την συγγραφή της εργασίας αυτής, απαραίτητη ήταν η δημιουργία ενός ερωτηματολογίου, απευθυνόμενο σε εκπαιδευτικούς πρωτοβάθμιας εκπαίδευσης. Το ερωτηματολόγιο αφορούσε την ποιότητα και την ποσότητα της γονεϊκής εμπλοκής στο σχολείο όπως την αντιλαμβάνονται και την έχουν βιώσει οι εκπαιδευτικοί και το κατά πόσο ο/η διευθυντής,-ντρια της εκάστοτε σχολικής μονάδας ενισχύει ή αποδυναμώνει τις συγκρούσεις που μπορεί να προκύψουν στο εκπαιδευτικό πλαίσιο. Τα αποτελέσματα της έρευνας αναλύθηκαν στο τελευταίο κεφάλαιο της εργασίας.
Comparing PTSD symptom networks in type I vs. type II trauma survivors
Creators: name: Stefanovic, Mina
name: Ehring, Thomas
name: Wittekind, Charlotte E.
name: Kleim, Birgit
name: Rohde, Judith
name: Krüger-Gottschalk, Antje
name: Knaevelsrud, Christine
name: Rau, Heinrich
name: Schäfer, Ingo
name: Schellong, Julia
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: PTSD
subject: trauma type
subject: network analysis
subject: Bayesian graphical Gaussian models
subject: network comparison
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: Background: Network analysis has gained increasing attention as a new framework to study complex associations between symptoms of post-traumatic stress disorder (PTSD). A number of studies have been published to investigate symptom networks on different sets of symptoms in different populations, and the findings have been inconsistent. Objective: We aimed to extend previous research by testing whether differences in PTSD symptom networks can be found in survivors of type I (single event; sudden and unexpected, high levels of acute threat) vs. type II (repeated and/or protracted; anticipated) trauma (with regard to their index trauma). Method: Participants were trauma-exposed individuals with elevated levels of PTSD symptomatology, most of whom (94%) were undergoing assessment in preparation for PTSD treatment in several treatment centres in Germany and Switzerland (n = 286 with type I and n = 187 with type II trauma). We estimated Bayesian Gaussian graphical models for each trauma group and explored group differences in the symptom network. Results: First, for both trauma types, our analyses identified the edges that were repeatedly reported in previous network studies. Second, there was decisive evidence that the two networks were generated from different multivariate normal distributions, i.e. the networks differed on a global level. Third, explorative edge-wise comparisons showed moderate or strong evidence for specific 12 edges. Edges which emerged as especially important in distinguishing the networks were between intrusions and flashbacks, highlighting the stronger positive association in the group of type II trauma survivors compared to type I survivors. Flashbacks showed a similar pattern of results in the associations with detachment and sleep problems (type II > type I). Conclusion: Our findings suggest that trauma type contributes to the heterogeneity in the symptom network. Future research on PTSD symptom networks should include this variable in the analyses to reduce heterogeneity.
Surface viscosity in simple liquids
Creators: name: Malgaretti, Paolo
name: Bafile, Ubaldo
name: Vallauri, Renzo
name: Jedlovszky, Pál
name: Sega, Marcello
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The response of Newtonian liquids to small perturbations is usually considered to be fully described by homogeneous transport coefficients like shear and dilatational viscosity. However, the presence of strong density gradients at the liquid/vapor boundary of fluids hints at the possible existence of an inhomogeneous viscosity. Here, we show that a surface viscosity emerges from the collective dynamics of interfacial layers in molecular simulations of simple liquids. We estimate the surface viscosity to be 8-16 times smaller than that of the bulk fluid at the thermodynamic point considered. This result can have important implications for reactions at liquid surfaces in atmospheric chemistry and catalysis.
Module 8. Data management plans (quiz and activity)
Creators: name: Cepinskas, Linas
Publisher: name: Zenodo
Year: 2021
Subjects: data management plan
DMP
researchers
data stewards
research data
research
data storage

description: This quiz, learning activity and resources are a part of the introductory online course “Bringing synergy to better data management and research in Europe”. The course helps learners get up to speed with innovative services and research data management approaches and do better research. The quiz will take about 10 minutes to complete. The learning activity on data storage will take another 10-15 minutes. The quiz is based on the online video presentation by Holmstrand, K.F., den Boer, S.P.A., Vlachos, E., Martínez-Lavanchy, P.M., Hansen, K.K. (Eds.) (2019). Research Data Management (e-Learning course). doi:10.11581/dtu:00000047 Developed within the EOSC Synergy project, all of the content can be freely shared and reused with the attribution to the EOSC Synergy project and/or other relevant sources. To make full use of the course (e.g. take quizzes), please register as a new user.
Growth Kinetic studies of ion beam sputtered AlN-thin films: Effect of reactive assistance of nitrogen plasma
Creators: name: Sharma, Neha
name: Prabhakar, K.
name: Ilango, S.
name: Dash, S.
name: Tyagi, A. K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences
subject: 00-02

description: Reactive dual ion beam sputter deposition of AlN thin films was carried out for the analysis of surface growth characteristics by Atomic Force Microscopy. The variation of roughness as a function of deposition time was analysed by Dynamic Scaling Theory (DST). Two distinct exponents, static and dynamic were used to unravel the film growth characteristics. As the deposition time increased, static scaling exponent decreased gradually and substrate surface coverage was increased which is indicated by a decrease in critical length Lc. The rms roughness of the film was increased from 1.99 to 3.42 nm as the deposition time was increased from 3 minutes to 15 minutes. Dynamic scaling exponent was found to be 0.36. During the growth, surface diffusion (n = 4) becomes the major roughening phenomenon while Bulk diffusion (n = 3) turns into the dominating smoothening phenomenon.
description: 10 pages, 8 figures
Flexible societies excelled in saving lives in the first phase of the COVID-19 pandemic
Creators: name: Li, Jianghong
name: Akaliyski, Plamen
name: Heisig, Jan Paul
name: Löbl, Simon
name: Minkov, Michael
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: COVID-19
subject: mortality
subject: national cultural traits
subject: flexibility-monumentalism
subject: mask wearing
subject: fear of catching COVID-19
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::301 Soziologie, Anthropologie

description: Background: Previous studies have shown that national cultural traits, such as collectivism–individualism and tightness–looseness, are associated with COVID-19 infection and mortality rates. However, although East Asian countries have outperformed other countries in containing COVID-19 infections and lowering mortality in the first pandemic waves, no studies to date have examined flexibility-monumentalism, a cultural trait that uniquely distinguishes East Asia from the rest of the world. Moreover, none of the previous studies have explored mechanisms underpinning the association between national culture and COVID-19 mortality. Aims: Our study fills in these gaps by examining the association between flexibility-monumentalism and COVID-19 mortality, adjusting for important covariates and by analyzing mask wearing and fear of COVID-19 during the first weeks of the pandemic as plausible mechanisms underpinning this association. Methods: We constructed and analyzed a dataset including 37 countries that have valid information on flexibility-monumentalism, COVID-19 deaths as of 31 October 2020 (before the start of vaccination campaigns), and relevant covariates including two other national cultural traits (individualism–collectivism and tightness–looseness) and other national characteristics (economic, political, demographic and health). Multiple linear regression with heteroscedasticity-consistent standard errors was used to assess the independent effect of flexibility-monumentalism on COVID-19 mortality. Mediation was assessed by examining the indirect effects of flexibility through mask wearing and fear of COVID-19 and determining the statistical significance through bootstrapping. Graphical and delete-one analysis was used to assess the robustness of the results. Results: We found that flexibility was associated with a significant reduction in COVID-19 mortality as of 31 October 2020, independent of level of democracy, per capita GDP, urbanization, population density, supply of hospital beds, and median age of the population. This association with mortality is stronger and more robust than for two other prominent national cultural traits (individualism–collectivism and tightness–looseness). We also found tentative evidence that the effect of flexibility on COVID-19 mortality may be partially mediated through mask wearing in the first weeks of the pandemic.
Objective derivation of macroinvertebrate family sensitivity grade numbers for the SIGNAL biotic index: Application to the Hunter River system, New South Wales
Creators: name: Chessman, Bruce C
name: Growns, Jane E
name: Kotlash, Amanda R
Publisher: name: La Trobe
Year: 2023

description: MDFRC item.

Chessman's SIGNAL-95 biotic index was modified on the basis of data from spring and autumn surveys of macroinvertebrates at 42 sites in the Hunter River and tributaries. An iterative algorithm was used to derive improved grade numbers reflecting the pollution sensitivities of individual families of river macroinvertebrates. The new grades were used to calculate values of the modified index (SIGNAL-HU97). These values were highly correlated with SIGNAL-95 values but were more widely spread, giving better discrimination between the sites of higher environmental quality and the more degraded sites. SIGNAL-HU97 values were also more highly correlated than were SIGNAL-95 values with environmental variables such as the conductivity of the water and a riparian, channel and environmental inventory. There was little difference in values between spring and autumn, but riffles consistently had higher mean values than other habitats.
Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample
Creators: name: Sullivan, P F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Although copy number variants (CNVs) are important in genomic medicine, CNVs have not been systematically assessed for many complex traits. Several large rare CNVs increase risk for schizophrenia (SCZ) and autism and often demonstrate pleiotropic effects; however, their frequencies in the general population and other complex traits are unknown. Genotyping large numbers of samples is essential for progress. Large cohorts from many different diseases are being genotyped using exome-focused arrays designed to detect uncommon or rare protein-altering sequence variation. Although these arrays were not designed for CNV detection, the hybridization intensity data generated in each experiment could, in principle, be used for gene-focused CNV analysis. Our goal was to evaluate the extent to which CNVs can be detected using data from one particular exome array (the Illumina Human Exome Bead Chip). We genotyped 9, 100 Swedish subjects (3, 962 cases with SCZ and 5, 138 controls) using both standard GWAS arrays and exome arrays. In comparison to CNVs detected using GWAS arrays, we observed high sensitivity and specificity for detecting genic CNVs ≥400 kb including known pathogentic CNVs along with replicating the literature finding that cases with SCZ had greater enrichment for genic CNVs. Our data confirm the association of SCZ with 16p11.2 duplications and 22q11.2 deletions and suggest a novel association with deletions at 11q12.2. Our results suggest the utility of exome focused arrays in surveying large genic CNVs in very large samples; and thereby open the door for new opportunities such as conducting well-powered CNV assessment and comparisons between different diseases. The use of a single platform also minimizes potential confounding factors that could impact accurate detection.
A Multiwavelength Classification and Study of Red Supergiant Candidates in NGC 6946
Creators: name: Johnson, Jared R.
name: Koplitz, Brad
name: Williams, Benjamin F.
name: Dalcanton, Julianne J.
name: Dolphin, Andrew
name: Girardi, Leo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We have combined resolved stellar photometry from Hubble Space Telescope (\emph{HST}), \emph{Spitzer}, and \emph{Gaia} to identify red supergiant (RSG) candidates in NGC~6946, based on their colors, proper motions, visual morphologies, and spectral energy distributions. We start with a large sample of 17,865 RSG candidates based solely on \emph{HST} near-infrared photometry. We then chose a small sample of 385 of these candidates with Spitzer matches for more detailed study. Using evolutionary models and isochrones, we isolate a space where RSGs would be found in our photometry catalogs. We then visually inspect each candidate and compare to Gaia catalogs to identify and remove foreground stars. As a result, we classify 95 potential RSGs, with 40 of these being in our highest-quality sample. We fit the photometry of the populations of stars in the regions surrounding the RSGs to infer their ages. Placing our best candidate RSG stars into three age bins between 1 and 30 Myr, we find 27.5\% of the candidates falling between 1-10 Myr, 37.5\% between 10-20 Myr, and 35\% 20-30 Myr. A comparison of our results to the models of massive star evolution shows some agreement between model luminosities and the luminosities of our candidates for each age. Three of our candidates appear significantly more consistent with binary models than single-star evolution models.
description: 32 pages, 18 figures, 4 tables
Identification of tidal features in deep optical galaxy images with Convolutional Neural Networks
Creators: name: Sánchez, H. Domínguez
name: Martin, G.
name: Damjanov, I.
name: Buitrago, F.
name: Huertas-Company, M.
name: Bottrell, C.
name: Bernardi, M.
name: Knapen, J. H.
name: Vega-Ferrero, J.
name: Hausen, R.
name: Kado-Fong, E.
name: Población-Criado, D.
name: Souchereau, H.
name: Leste, O. K.
name: Robertson, B.
name: Sahelices, B.
name: Johnston, K. V.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Interactions between galaxies leave distinguishable imprints in the form of tidal features which hold important clues about their mass assembly. Unfortunately, these structures are difficult to detect because they are low surface brightness features so deep observations are needed. Upcoming surveys promise several orders of magnitude increase in depth and sky coverage, for which automated methods for tidal feature detection will become mandatory. We test the ability of a convolutional neural network to reproduce human visual classifications for tidal detections. We use as training $\sim$6000 simulated images classified by professional astronomers. The mock Hyper Suprime Cam Subaru (HSC) images include variations with redshift, projection angle and surface brightness ($μ_{lim}$ =26-35 mag arcsec$^{-2}$). We obtain satisfactory results with accuracy, precision and recall values of Acc=0.84, P=0.72 and R=0.85, respectively, for the test sample. While the accuracy and precision values are roughly constant for all surface brightness, the recall (completeness) is significantly affected by image depth. The recovery rate shows strong dependence on the type of tidal features: we recover all the images showing shell features and 87% of the tidal streams; these fractions are below 75% for mergers, tidal tails and bridges. When applied to real HSC images, the performance of the model worsens significantly. We speculate that this is due to the lack of realism of the simulations and take it as a warning on applying deep learning models to different data domains without prior testing on the actual data.
description: 13 pages, 10 figures, accepted for publication in MNRAS
Double layers in gravity theories
Creators: name: Senovilla, José M. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Gravitational double layers, unlike their classical electromagnetic counterparts, are thought to be forbidden in gravity theories. It has been recently shown, however, that they are feasible in, for instance, gravity theories with a Lagrangian quadratic in the curvature. This is surprising with many potential consequences and the possibility of new physical behaviours. While a clear interpretation seems elusive, several lines of research are open. I present the field equations for double layers, the new physical quantities arising, and several explicit examples.
description: 11 pages, no figures. Invited talk at the Spanish Relativity Meeting 2014 (ERE-2014), submitted to its Proceedings
A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling
Creators: name: Hebebrand, J
name: Kiezebrink, K
name: Klump, K L
name: Raevuori, A
name: Reichborn-Kjennerud, T
name: Gorwood, P
name: Van Furth, E F
name: Santonastaso, P
name: Dmitrzak-Weglarz, M
name: Boraska, V
name: Slof-Op 't Landt, M C T
name: Knudsen, G P S
name: Schmidt, U
name: Huckins, L M
name: Adan, R A H
name: Franklin, C S
name: Gratacos, M
name: Kas, M J H
name: Lewis, C M
name: Favaro, A
name: Southam, L
name: Thornton, L M
name: Tozzi, F
name: Rayner, N W
name: Treasure, J
name: Kaprio, J
name: Fernández-Aranda, F
name: Hudson, J I
name: Rybakowski, F
name: Keski-Rahkonen, A
name: Floyd, J A B
name: Tachmazidou, I
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome wide association study (GWAS) have yielded significant and replicated results. We performed a GWAS in 2,907 cases with AN from 14 countries (15 sites) and 14,860 ancestrally matched controls as part of the Genetic Consortium for AN (GCAN) and the Wellcome Trust Case Control Consortium 3 (WTCCC3). Individual association analyses were conducted in each stratum and meta-analyzed across all 15 discovery datasets. Seventy-six (72 independent) SNPs were taken forward for in silico (two datasets) or de novo (13 datasets) replication genotyping in 2,677 independent AN cases and 8,629 European ancestry controls along with 458 AN cases and 421 controls from Japan. The final global meta-analysis across discovery and replication datasets comprised 5,551 AN cases and 21,080 controls. AN subtype analyses (1,606 AN restricting; 1,445 AN binge-purge) were performed. No findings reached genome-wide significance. Two intronic variants were suggestively associated: rs9839776 (P=3.01×10-7) in SOX2OT and rs17030795 (P=5.84×10-6) in PPP3CA. Two additional signals were specific to Europeans: rs1523921 (P=5.76×10-6) between CUL3 and FAM124B and rs1886797 (P=8.05×10-6) near SPATA13. Comparing discovery to replication results, 76% of the effects were in the same direction, an observation highly unlikely to be due to chance (P=4×10-6), strongly suggesting that true findings exist but that our sample, the largest yet reported, was underpowered for their detection. The accrual of large genotyped AN case-control samples should be an immediate priority for the field.
Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function and bipolar disorder susceptibility
Creators: name: Gan, L
name: Li, M
name: Gill, M
name: Czamara, D
name: Shi, H
name: Corvin, A
name: Lin, Q
name: Bergen, S E
name: Donohoe, G
name: Müller-Myhsok, B
name: Toga, A W
name: Luo, X-j
name: Ikram, M A
name: Thompson, P M
name: Meyer-Lindenberg, A
name: Shi, L
name: Hargreaves, A
name: Bis, J C
name: Landén, M
name: Lewis, C M
name: Mattheisen, M
name: Jamain, S
name: Rietschel, M
name: Cichon, S
name: Hultman, C
name: Etain, B
name: Leboyer, M
name: Morris, D W
name: Henry, C
name: Nöthen, M M
name: Schulze, T G
name: Sullivan, P F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Bipolar disorder (BD) is a polygenic disorder that shares substantial genetic risk factors with major depressive disorder (MDD). Genetic analyses have reported numerous BD susceptibility genes, while some variants, such as single-nucleotide polymorphisms (SNPs) in CACNA1C have been successfully replicated, many others have not and subsequently their effects on the intermediate phenotypes cannot be verified. Here, we studied the MDD-related gene CREB1 in a set of independent BD sample groups of European ancestry (a total of 64 888 subjects) and identified multiple SNPs significantly associated with BD (the most significant being SNP rs6785[A], P = 6.32 × 10−5, odds ratio (OR) = 1.090). Risk SNPs were then subjected to further analyses in healthy Europeans for intermediate phenotypes of BD, including hippocampal volume, hippocampal function and cognitive performance. Our results showed that the risk SNPs were significantly associated with hippocampal volume and hippocampal function, with the risk alleles showing a decreased hippocampal volume and diminished activation of the left hippocampus, adding further evidence for their involvement in BD susceptibility. We also found the risk SNPs were strongly associated with CREB1 expression in lymphoblastoid cells (P<0.005) and the prefrontal cortex (P<1.0 × 10−6). Remarkably, population genetic analysis indicated that CREB1 displayed striking differences in allele frequencies between continental populations, and the risk alleles were completely absent in East Asian populations. We demonstrated that the regional prevalence of the CREB1 risk alleles in Europeans is likely caused by genetic hitchhiking due to natural selection acting on a nearby gene. Our results suggest that differential population histories due to natural selection on regional populations may lead to genetic heterogeneity of susceptibility to complex diseases, such as BD, and explain inconsistencies in detecting the genetic markers of these diseases among different ethnic populations.
(:unas) unassigned
Creators: name: (:Unkn) Unknown
Publisher: name: Universita' degli Studi di Salerno
Year: 2024

description: Tesori musicali nascosti è un sito internet avviato nel 2023, anche in collaborazione con il Centro di Studi Tassiani, in occasione dell’anno in cui Bergamo e Brescia sono Capitale italiana della Cultura. L’iniziativa ha finalità principalmente didattiche e divulgative: non è un database, ma uno strumento multimediale che si presenta come “Museo virtuale della musica” per offrire ai fruitori una scelta ragionata di beni musicali storicamente e artisticamente rilevanti.
description: Tesori musicali nascosti (Hidden Musical Treasures) is a website launched in 2023, also in collaboration with the Tasso Studies Center, on the occasion of the year when Bergamo and Brescia are the Italian Capitals of Culture. This initiative is primarily educational and informative: it is not a database but a multimedia tool that presents itself as a “Virtual Museum of Music” to provide users with a thoughtful selection of historically and artistically significant musical assets.
Let's discuss about FAIRifying OS policies
Creators: name: Van Wezel, Jos
name: Matthews, Brian
name: Davidson, Joy
name: Růžička, Michal
name: Electra Sifakaki
name: Nadina Fogetti
Publisher: name: Zenodo
Year: 2021
Subjects: Open Science policies
Open Science
IPR
GDPR
International collaborations
Data Management Planning
PIDs
Legal

description: The development and alignment of policies relating to Open Science (OS) are crucial for the successful implementation of the European Open Science Cloud (EOSC). Currently, a multitude of policies exist at various levels (national, funding body, publisher and organisational). Among these, there are observable differences in the expectations on researchers around data management planning, data handling, and data accessibility. The lack of harmonisation across these policies causes confusion among those who need to comply with them, limit cross institutional data use and can hinder rather support uptake of Open Science practices. For example, there are great variations in how data protection and intellectual property are addressed and there could be legal consequences that a researcher in an international collaboration may need to be aware of. To avoid difficulties, the content of the policies themselves needs to be made FAIR to enable clear comparison by both human and machines. Several INFRAEOSC projects have been working to develop recommendations to facilitate policy alignment across the European Research Area with the ultimate aim of realising the EOSC vision. In this workshop, organised by the InfraEOSC-5 Task Force on National Policies and Governance, we will introduce some of the practical recommendations relating to the findability, accessibility, interoperability and reuse of OS policies and work to collectively draft a set of “5 key actions towards common open science policies”. This workshop is targeted toward policymakers and members of transnational collaborations at all levels and aims to foster the emergence of a community of practice that can help put the 5 key actions into practice.