cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Floquet analysis of the modulated two-mode Bose-Hubbard model
Creators: name: Watanabe, Gentaro
name: Mäkelä, Harri
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Nuclear Theory (nucl-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the tunneling dynamics in a time-periodically modulated two-mode Bose-Hubbard model using Floquet theory. We consider situations where the system is in the self-trapping regime and either the tunneling amplitude, the interaction strength, or the energy difference between the modes is modulated. In the former two cases, the tunneling is enhanced in a wide range of modulation frequencies, while in the latter case the resonance is narrow. We explain this difference with the help of Floquet analysis. If the modulation amplitude is weak, the locations of the resonances can be found using the spectrum of the non-modulated Hamiltonian. Furthermore, we use Floquet analysis to explain the coherent destruction of tunneling (CDT) occurring in a large-amplitude modulated system. Finally, we present two ways to create a NOON state (a superposition of $N$ particles in mode 1 with zero particles in mode 2 and vice versa). One is based on a coherent oscillation caused by detuning from a partial CDT. The other makes use of an adiabatic variation of the modulation frequency. This results in a Landau-Zener type of transition between the ground state and a NOON-like state.
description: 16 pages, 11 figures; published in Phys. Rev. A
Status of the Inert Doublet Model and the Role of multileptons at the LHC
Creators: name: Gustafsson, Michael
name: Rydbeck, Sara
name: Lopez-Honorez, Laura
name: Lundstrom, Erik
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A possible feature of the inert doublet model (IDM) is to provide a dark matter candidate together with an alteration of both direct and indirect collider constraints that allow for a heavy Higgs boson. We study the IDM in light of recent results from Higgs searches at the Large Hadron Collider (LHC) in combination with dark matter direct detection limits from the XENON experiment. We ask under what conditions the IDM can still accommodate a heavy Higgs boson. We find that IDM scenarios with a Higgs boson in the mass range 160-600 GeV are ruled out only when all experimental constraints are combined. For models explaining only a fraction of the dark matter the limits are weakened, and IDMs with a heavy Higgs are allowed. We discuss the prospects for future detection of such IDM scenarios in the four-lepton plus missing energy channel at the LHC. This signal can show up in the first year of running at \sqrt{s} = 14 TeV, and we present detector-level studies for a few benchmark models.
description: Matches published version apart from: A note added on 126 GeV SM scalar mass including a table of viable benchmark models, and a typo corrected in Eq. 3. (23 pages, 10 figures and 7 tables)
Unawareness of head tremor in essential tremor : a study of three samples of essential tremor patients
Creators: name: Louis, Elan D.
name: Pellegrino, Kathryn M.
name: Rios, Eileen
Publisher: name: Columbia University
Year: 2008
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Patients with Huntington disease may be unaware of their chorea, and patients with Parkinson disease often do not recognize or endorse their medication-induced dyskinesias.1, 2 Head tremor occurs in essential tremor (ET),3, 4 yet patients in our experience are often unaware of it. While this phenomenon is anecdotally noted, it has not been formally documented or studied systematically.
title: Dom Thierry Ruinart
title: An entry in the LCA Online Dictionary of Leibniz’s Correspondents and Acquaintances
titleType: Subtitle
Creators: name: (:Tba)
Publisher: name: LCA Project
Year: 2018

description: Dom Thierry Ruinart as a personal relation of Leibniz’s: The resource presents biographical information on a correspondent of Leibniz's
title: Culture, combat and killing : a comparative study of the British armed forces at war in the Falklands
Creators: name: Johnston, Peter
Publisher: name: University of Kent
Year: 2021

description: This thesis utilises the direct memories of combat veterans to, explore the importance of issues such as culture and combat arena and role to the experience of combat and killing. By utilising oral history, in conjunction with retrospective memoirs and contemporary documentary sources, I have compiled and collated a variety of experience in order to illustrate how war impacts at the personal level, and the social bonds and processes that become essential in combat. The thesis explores the role of men in combat, how they related to the act of killing, and how that experience differed in various combat arenas, be it land, sea or air. It is a comparative study of the social and cultural forces present in the British armed forces, and how they mediated and dictated the combat and killing, by comparing the experiences of soldiers, sailors and airmen. The variety of experience has allowed one to analyse and identify salient trends in military culture, and the long-term consequences and enduring nature of these aspects of military life on the individual. The conflict analysed in this study is the Falklands War of 1982. While short in duration, as the last war fought by the British outside of an international coalition, it was a truly British conflict, and as such the attitudes and reactions to the experience of war were not clouded by external cultures. It also involved all three branches of the armed forces in direct combat, providing the opportunity to analyse how combat environments and weapons shape experience. Significantly, the war was also fought by professionals, who had joined the military in a time of peace. While considerable work has been done in analysing combat experience, it is predominately dedicated to the First and Second World Wars, instances where the majority of participants were civilians in uniform. Yet the experiences of professional servicemen at war were remarkably different and merit further study. This dissertation seeks to continue the trend of analysis of individual combat experience, but in contrast this research seeks to place the experience of the professional British serviceman in its proper context, alongside his historical predecessor, in order to help chart how the cultural responses to combat have changed over the twentieth century for those who have experienced it in all of the combat arenas.
Higher blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations correlate with lower olfactory scores in essential tremor
Creators: name: Louis, Elan D.
name: Rios, Eileen
name: Pellegrino, Kathryn M.
name: Jiang, Wendy
name: Factor-Litvak, Pam
name: Zheng, Wei
Publisher: name: Columbia University
Year: 2008
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Harmane (1-methyl-9H-pyrido[3,4-b]indole), a neurotoxin, may be an environmental risk factor for essential tremor (ET). Harmane and related chemicals are toxic to the cerebellum. Whether it is through this mechanism (cerebellar toxicity) that harmane leads to ET is unknown. Impaired olfaction may be a feature of cerebellar disease.
"[I]f it makes no sense then you understand it perfectly:” exploring ideas of fundamental freedoms in the theatrical legacy of Sarah Kane
Creators: name: Klupková, Petra
Publisher: name: University of British Columbia
Year: 2013

description: This Thesis uses Sarah Kane’s first and last plays, Blasted and 4.48 Psychosis, as case studies to show Kane’s development in appealing to contemporary history through performance, both as an act of warning against lethargy and as an opportunity to consider the extent to which issues can be represented as unmediated, outside of social structures, outside of the logic given by law or religion, and outside of the lobbying of various interest groups. Both plays are assessed not only as referencing their own period—Blasted as urgently calling attention to the globally long-ignored genocide in Bosnia, and 4.48 Psychosis as a critique of mental institutions in the context of the further formalization of human rights in the UK—but also as having a significant potential for future performances highly relevant in more current political and social contexts, such as, for example, the humanitarian crisis in Darfur (Sudan), only one of 17 United Nations peace operations on four continents, or the case of Tony Nicklinson and his fight to legally end his life. In her exploration of the relationships between oppressor and oppressed, Kane recreates in her theatrical form a similar relationship of abuse between stage and audience. By recreating a sense of community within the space of the theatre and reinforcing awareness of a shared responsibility, Kane enters the public arena of global politics and confronts her audience with the question: ‘Are you/will you remain only an audience member, or do you decide to act?’
title: Andreas Wolfgang von Runckel
title: An entry in the LCA Online Dictionary of Leibniz’s Correspondents and Acquaintances
titleType: Subtitle
Creators: name: (:Tba)
Publisher: name: LCA Project
Year: 2018

description: Andreas Wolfgang von Runckel as a personal relation of Leibniz’s: The resource presents biographical information on a correspondent of Leibniz's
Le insegne ed i protocolli d’ascesa da Teodosio I a Giustino II: funzionalità e significatività dei segni dell’eccellenza del rango
Creators: name: Di Cosmo, Antonio Pio
Publisher: name: HISTORIKA Studi di storia greca e romana
Year: 2023

description: Il presente contributo analizza il ruolo giocato dai segni del potere imperiale ed in particolare delle insegne nei riti di elezione fra IV e VI secc.. Questa ricerca applica le conoscenze in materia archeologica, antropologica e storica. Si racconta il rituale di elezione e si risolvono le questioni circa i problemi di rappresentazione dell’augusto nelle cerimonie d’ascesa. In questo modo si vagliano le strategie di comunicazione che modellano i protocolli di creazione degli augusti.
description: HISTORIKA Studi di storia greca e romana, V. 12 (2022)
STUDIO CLINICO_Registro Italiano sulla Sindrome di Brugada 485.2021
Creators: name: MultiMedica Data Management
Publisher: name: Zenodo
Year: 2025

description: STUDIO CLINICO_Registro Italiano sulla Sindrome di Brugada 485.2021

 TITOLO :   Registro Italiano sulla Sindrome di Brugada

Promotore: Istituto Auxologico Italiano

Studio osservazionale di registro prospettico multicentrico nazionale

Lettera di richiesta del Promotore al CE 20.12.2020  con lettera di integrazione  01.12.2020

Verbale CE 56.2021

IL PROMOTORE autorizza MultiMedica a registrare su Piattaforma ZENODO lo studio Brugada per le finalità di rendicontazione ministeriale. Al momento della chiusura del WorkFlow il codice di registrazione di ClinicalTrials.gov non è rilasciato.
L’oral réflexif repensé au regard d’une gestion de la classe responsabilisante : impacts d’une recherche sur la formation initiale en didactique de l’oral
Creators: name: RICS, Revue
name: Sénéchal, Kathleen
name: Messier, Geneviève
name: Dumouchel, Mélanie
Publisher: name: figshare
Year: 2021
Subjects: Education

description: Notre équipe mène actuellement une étude dont l’objectif est de coconstruire, avec des enseignants du primaire (n=12), des pratiques d’enseignement soutenant le développement des compétences en littératie des élèves par la mise en œuvre de l’oral réflexif. Ce dernier implique une redistribution du temps de parole entre l’enseignant et les élèves, ce qui se fait normalement en adoptant une gestion de la classe responsabilisante. Considérant que les pratiques de gestion de la classe sont depuis longtemps identifiées par les enseignants comme l’un des principaux défis relatifs à leur insertion professionnelle, nous avons jugé indispensable de réfléchir conjointement aux choix didactiques et de gestion de la classe. Cette contribution est donc l’occasion de présenter les impacts de la réalisation des étapes préparatoires de notre recherche sur la formation initiale à l’enseignement de la communication orale, plus particulièrement en ce qui a trait à la planification de séquences d’enseignement tenant compte des différentes dimensions de l’acte d’enseigner.
Common misdiagnosis of a common neurological disorder : how are we misdiagnosing essential tremor?
Creators: name: Jain, Samay
name: Lo, Steven E.
name: Louis, Elan D.
Publisher: name: Columbia University
Year: 2006
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Background: As a common neurological disorder, the diagnosis of essential tremor (ET) is considered routine. Despite this, previous work suggests that misdiagnoses may be common. Among other things, these misdiagnoses can lead to treatment errors. Objectives: To estimate how often other tremor disorders are misdiagnosed as ET and to identify factors that increase the odds of misdiagnosing ET and to precisely quantify the extent to which they do so. Design: Seventy-one consecutive patients underwent an evaluation at the Neurological Institute of New York, New York, between January 1, 2000, and December 31, 2005; these patients had a preevaluation diagnosis of ET. The criteria for ET were adapted from the consensus statement of the Movement Disorder Society. Results: Twenty-six patients (37%) were misdiagnosed as having ET ("false ET"). Their true diagnoses were Parkinson disease (11 patients [15%]), dystonia (6 patients [8%]), Parkinson disease with ET (5 patients [7%]), and other disorders (4 patients [6%]). Factors associated with misdiagnosed ET included unilateral arm tremor (odds ratio, 10.5; 95% confidence interval, 1.2-95.4; P=.02), spooning of the hands and other dystonic postures (odds ratio, 16.3; 95% confidence interval, 4.0-66.4; P
Coexisting order and disorder hidden in a quasi-two-dimensional frustrated magnet
Creators: name: Iida, K.
name: Lee, S. -H.
name: Cheong, S. -W.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Frustrated magnetic interactions in a quasi-two-dimensional [111] slab of pyrochlore lattice were studied. For uniform nearest neighbor (NN) interactions, we show that the complex magnetic problem can be mapped onto a model with two independent degrees of freedom, tri-color and binary sign. This provides a systematic way to construct the complex classical spin ground states with collinear and coplanar bi-pyramid spins. We also identify `partial but extended' zero-energy excitations amongst the ground states. For nonuniform NN interactions, the coplanar ground state can be obtained from the collinear bi-pyramid spin state by collectively rotating two spins of each tetrahedron with an angle, $α$, in an opposite direction. The latter model with $α\sim 30^\circ$ fits the experimental neutron data from SCGO well.
description: 5 pages, 5 figures
Surface ligands in the imprinting and binding of molecularly imprinted cross-linked micelles
Creators: name: Arifuzzaman, MD
name: Zhao, Wei
name: Zhao, Yan
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Molecular recognition in water is challenging but water-soluble molecularly imprinted nanoparticle (MINP) receptors were produced readily by double cross-linking of surfactant micelles in the presence of suitable template molecules. When the micellar surface was decorated with different polyhydroxylated ligands, significant interactions could be introduced between the surface ligands and the template. Flexible surface ligands worked better than rigid ones to interact with the polar moiety of the template, especially for those template molecules whose water-exposed surface is not properly solvated by water. The importance of these hydrophilic interactions was examined in the context of different substrates, density of the surface ligands, and surface-cross-linking density of the MINP. Together with the hydrophobic interactions in the core, the surface hydrophilic interactions can be used to enhance the binding of guest molecules in water.
Factor analysis of motor and nonmotor signs in essential tremor : are these signs all part of the same underlying pathogenic process?
Creators: name: Louis, Elan D.
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Essential tremor (ET) has traditionally been viewed as monosymptomatic. However, there is an emerging appreciation of an expanded number of motor manifestations as well as a new awareness of nonmotor manifestations. The current goal, through factor analyses, was to determine how these diverse signs relate to one another and shed light on their pathogenic bases. One hundred and thirty-eight ET patients had detailed neurological examinations. In these analyses, three separate factors emerged, explaining 58.7% of the variance. Factor I was comprised of the hallmark feature of ET, action tremor. It also included intention tremor, which is generally viewed as a sign of cerebellar dysfunction, and tremor duration. Factor II was comprised of cognitive test scores and age, and factor III, of rest tremor. Cognitive test scores did not fall into the same domain as motor features or tremor duration. These results suggest that: (1) the process that underlies cognitive dysfunction in ET is distinct from that which is responsible for action and intention tremors and their progression over time, and (2) cognitive dysfunction in ET is not likely due to cerebellar degeneration. Age loaded with cognitive test scores, further raising the possibility that age-related processes (e.g. Alzheimer-type changes) could underlie cognitive changes in ET.
Kinetic tremor : differences between smokers and non-smokers
Creators: name: Louis, Elan D.
Publisher: name: Columbia University
Year: 2007
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Tremor is among the acute effects of nicotine exposure. Published studies have focused on smoking-related postural (static) hand tremor rather than kinetic tremor (tremor during hand use), and gender differences in smoking-related tremor have not been examined. In a group of adults who were sampled from a population (mean ± S.D. = 65.7 ± 11.5 years, range = 18–92 years), the investigator assessed whether the severity of postural and kinetic tremors differed in smokers versus non-smokers, and whether this difference was influenced by gender. Twenty-seven (9.9%) of 273 subjects were current smokers. Greater tremor was observed in smokers than non-smokers during a variety of activities (drawing a spiral, using a spoon, finger–nose–finger maneuver, all p < 0.05) and smokers had a higher total tremor score than non-smokers (5.15 ± 3.06 versus 3.41 ± 2.88, p < 0.01), even after adjusting for age, caffeine intake and other potential confounding factors. The difference between smokers and non-smokers in terms of hand tremor was more apparent in women than in men. In women, the number of cigarettes smoked on the day of testing was weakly correlated with the total tremor score (r = 0.17, p = 0.03). In summary, smokers had more kinetic hand tremor than non-smokers. This difference between smokers and non-smokers was more apparent in women than in men. These results suggest that smoking habits should be considered carefully in order to avoid over- or underestimating the effects of occupational and non-occupational exposures to other tremor-producing neurotoxins.
Observation of explosive collisionless reconnection in 3D nonlinear gyrofluid simulations
Creators: name: Biancalani, Alessandro
name: Scott, Bruce D.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The nonlinear dynamics of collisionless reconnecting modes is investigated, in the framework of a three-dimensional gyrofluid model. This is the relevant regime of high-temperature plasmas, where reconnection is made possible by electron inertia and has higher growth rates than resistive reconnection. The presence of a strong guide field is assumed, in a background slab model, with Dirichlet boundary conditions in the direction of nonuniformity. Values of ion sound gyro-radius and electron collisionless skin depth much smaller than the current layer width are considered. Strong acceleration of growth is found at the onset to nonlinearity, while at all times the energy functional is well conserved. Nonlinear growth rates more than one order of magnitude higher than linear growth rates are observed when entering into the small-$Δ'$ regime.
Grassroots Disaster Recovery Planning: New Orleans and Beyond
Creators: name: Neville, Jason
name: Irazabal Zurita, Clara E.
Publisher: name: Columbia University
Year: 2007
Subjects: City planning

description: Weeks have turned to months and months to years as New Orleanians both those living in the city and those yet to return have waited in vain for leadership and resources from local, state and federal sources. In the face of such neglect, and united with a determination to rebuild their lives and communities, many residents and grassroots organizations have begun planning for their devastated communities on their own. Attendees at this year's Planners Network conference in New Orleans were intimately exposed to these grassroots phenomena through community-based panels and workshops. While most planners that have come to New Orleans have typically spent their time promoting their own ideas for the city's recovery, the conference attendees embarked on a kind of "listening tour" in this increasingly plan-weary town. Whether touring the city's commercial recovery areas by bike, helping gut a new community center outside the St. Bernard housing project or visiting a community-based urban design project hosted by residents, Planners Network members got to see and hear about the community-based recovery efforts led by residents and grassroots leaders.
title: Johann Saal von Heppenheim
title: An entry in the LCA Online Dictionary of Leibniz’s Correspondents and Acquaintances
titleType: Subtitle
Creators: name: (:Tba)
Publisher: name: LCA Project
Year: 2018

description: Johann Saal von Heppenheim as a personal relation of Leibniz’s: The resource presents biographical information on a correspondent of Leibniz's
title: Connections and contradictions : the social psychology of conspiracy theories
Creators: name: Wood, Michael James
Publisher: name: University of Kent
Year: 2021

description: Conspiracy theories are an ever more prominent part of modern social and political discourse. While an increasing amount of psychological research has been devoted to investigating the determinants of conspiracism, there is no overarching theoretical perspective that can unify the field's disparate findings . In the present thesis, we develop and test a novel theoretical framework that we call extended monological belief system theory. The theory, based on well-established models of cognitive consistency and parallel constramt satisfaction, proposes that beliefs in conspiracy theories are best understood as fairly vague outward manifestations of broader underlying beliefs and attitudes which together serve to construct a conspiratorial worldview. In a series often empirical studies we demonstrate that contradictory conspiracy theories are correlated in belief, that these correlations are at least partially explained by higher-order beliefs, and that the correlations are not reliably found for conventional explanations; that conspiracists prefer to make arguments based on refuting official narratives rather than proposing specific alternatives; and that interpersonal suspicion appears to be a natural outcome of reading pro-conspiracist persuasive texts. Moreover, connectionist models built on the architecture of the model accurately predicted behavioural responses to fictitious conspiracy scenarios. The results indicate that the degree to which Someone believes in a conspiracy theory is determined less by the details of the theory and more by the degree to which the theory matches that person's higher-order beliefs. Based on these results and on the current state of the literature on the psychology of conspiracism, we propose that extended monological belief system theory can be used as a framework for understanding the contributions of beliefs, attitudes, individual-difference variables, and various other contributors to beliefs in conspiracy theories.
Ricezione e rielaborazione della figura di Sertorio dalla tarda antichità al Novecento
Creators: name: Bossola, Stefano
Publisher: name: HISTORIKA Studi di storia greca e romana
Year: 2023

description: L’episodio sertoriano godette di alterne fortune nel corso della storia fino alla sua definitiva riscoperta nel corso dell’Ottocento. Ogni epoca e ogni contesto sfruttarono il personaggio di Sertorio in modo diverso per rispondere alle proprie esigenze e ne diedero una lettura influenzata dall’immaginario e dalle idee di ciascun periodo. La sua fu una figura in grado per lungo tempo di colpire la sensibilità di coloro che ad essa si approcciavano, dando luogo ad una grande varietà di spunti. Se il Cinquecento fu il periodo in cui il fenomeno della ricezione della figura di Sertorio raggiunse il proprio apice, l’Ottocento segnò l’inizio del progressivo declino dell’interesse verso tale personaggio, consegnato unicamente agli studi antichistici. Questo articolo intende dunque analizzare i processi di ricezione e rielaborazione che coinvolsero la figura di Sertorio a partire dall’epoca tardo antica fino ai giorni nostri.
description: HISTORIKA Studi di storia greca e romana, V. 12 (2022)
Mild Parkinsonian signs are associated with lower olfactory test scores in the community-dwelling elderly
Creators: name: Louis, Elan D.
name: Marder, Karen
name: Tabert, Matthias H.
name: Devanand, Devangere P.
Publisher: name: Columbia University
Year: 2008
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Mild Parkinsonian signs (MPS, impaired gait, rigidity, bradykinesia, rest tremor) are commonly found during the clinical examination of older people and may be a precursor to Parkinson's disease (PD) or Alzheimer's disease (AD). Marked deficits in olfaction occur in PD and AD. The objective of this study was to determine whether University of Pennsylvania Smell Test (UPSIT) scores were lower in nondemented community-dwelling elderly with versus without MPS. Nondemented persons age ≥65 years without PD in Washington Heights-Inwood, NY were evaluated with an abbreviated motor Unified PD Rating Scale and a 40-item UPSIT. Lower UPSIT and higher transformed UPSIT score (square root [UPSIT - 41]) indicated greater olfactory dysfunction. One-hundred-seventy-seven (16.4%) of 1,078 participants had MPS. Mean UPSIT scores (MPS vs. without MPS) were 24.3 ± 7.1 versus 26.4 ± 6.8, P < 0.001. In a logistic regression analysis adjusting for age and education, transformed UPSIT score was associated with MPS (OR 1.25, 95% CI 1.04–1.52, P = 0.02). In an adjusted logistic regression analysis, participants with higher transformed UPSIT scores (based on a median split) were 1.55 times more likely to have MPS than were those with lower scores (P = 0.01). Within transformed UPSIT score quartiles, the odds of having MPS were 1.0 (reference), 1.35, 2.02, and 2.20 (P < 0.05). The association with transformed UPSIT scores was similar across MPS subtypes (axial dysfunction, rigidity, tremor).MPS were associated with a mild reduction in olfactory function. These observations further support the view of MPS as a marker of emerging degenerative brain pathologies. © 2007 Movement Disorder Society.
Scaling of Traction Forces with Size of Cohesive Cell Colonies
Creators: name: Mertz, Aaron F.
name: Banerjee, Shiladitya
name: Che, Yonglu
name: German, Guy K.
name: Xu, Ye
name: Hyland, Callen
name: Marchetti, M. Cristina
name: Horsley, Valerie
name: Dufresne, Eric. R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Cell Behavior (q-bio.CB)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: To understand how the mechanical properties of tissues emerge from interactions of multiple cells, we measure traction stresses of cohesive colonies of 1-27 cells adherent to soft substrates. We find that traction stresses are generally localized at the periphery of the colony and the total traction force scales with the colony radius. For large colony sizes, the scaling appears to approach linear, suggesting the emergence of an apparent surface tension of order 1E-3 N/m. A simple model of the cell colony as a contractile elastic medium coupled to the substrate captures the spatial distribution of traction forces and the scaling of traction forces with the colony size.
description: 5 pages, 3 figures
title: A. I. Sachse
title: An entry in the LCA Online Dictionary of Leibniz’s Correspondents and Acquaintances
titleType: Subtitle
Creators: name: (:Tba)
Publisher: name: LCA Project
Year: 2018

description: A. I. Sachse as a personal relation of Leibniz’s: The resource presents biographical information on a correspondent of Leibniz's
Additional file 1 of Education and household income and carotid intima-media thickness in Japan: baseline data from the Aidai Cohort Study in Yawatahama, Uchiko, Seiyo, and Ainan
Creators: name: Miyake, Yoshihiro
name: Tanaka, Keiko
name: Senba, Hidenori
name: Hasebe, Yasuko
name: Miyata, Toyohisa
name: Higaki, Takashi
name: Kimura, Eizen
name: Matsuura, Bunzo
name: Kawamoto, Ryuichi
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. Supplementary Table 1. Characteristics of the 2012 study subjects in relation to educational level by age groupa.
Is Parkinson's disease-related mortality declining?
Creators: name: Haberfeld, Elizabeth
name: Louis, Elan D.
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Reports of trends in mortality from neurodegenerative disease have long relied on death
certificates registries and other nationally-administered databanks to determine the state and
direction of public health regarding these conditions. In this article, Mylne et. al. turned to the
Office of National Statistics, England to ascertain the death statistics for patients with
Parkinson's disease (PD) for the most recent time period available. Their findings are both
intriguing and encouraging, and deserve further comment.
Additional file 1 of The cell adhesion molecule TMIGD1 binds to moesin and regulates tubulin acetylation and cell migration
Creators: name: Rahimi, Nader
name: Ho, Rachel X. Y.
name: Chandler, Kevin Brown
name: De La Cena, Kyle Oliver Corcino
name: Amraei, Razie
name: Mitchel, Ashley J.
name: Engblom, Nels
name: Costello, Catherine E.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: Computational Biology

description: Additional file 1: Figure S1. Amino acid sequence homology of human moesin and ezrin. Alignment of human moesin (MSN) and ezrin (EZN) is shown. The FERM domain is shown in a box. Hydrophobic and negatively amino acids are highlighted in light blue and light brown colors, respectively. Figure S2. qPCR analysis of TMIGD1 KO mouse: qPCR analysis of wild-type and TMIGD1 is shown. Figure S3. Ectopic expression of Moesin and TMIGD1 in HEK-293 cell. Whole cell lysates derived from HEK-293 cells expressing TMIGD1 or moesin subjected to western blot analysis. Figure S4. TMIGD1, Moesin and Ezrin mRNA levels in human normal kidney verses kidney cancer types. A–C TMIGD1, Moesin and Ezrin mRNA levels obtained from the TCGA data set via Fire Brows ( http://firebrowse.org/ ). Kidney cancer types; kidney clear cell renal cell carcinoma (KIRC), kidney papillary renal cell carcinoma (KIRP), chromophobe renal cell carcinoma (KICH) and kidney pan cancer analysis (KIPAN). The horizontal small black bars within each box correspond to median expression of given proteins.
title: Caspar Sagittarius
title: An entry in the LCA Online Dictionary of Leibniz’s Correspondents and Acquaintances
titleType: Subtitle
Creators: name: (:Tba)
Publisher: name: LCA Project
Year: 2018

description: Caspar Sagittarius as a personal relation of Leibniz’s: The resource presents biographical information on a correspondent of Leibniz's
Intention tremor in essential tremor : prevalence and association with disease duration
Creators: name: Louis, Elan D.
name: Frucht, Steven
name: Rios, Eileen
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Scholarly attention only recently has been focused on intention tremor (IT) in essential tremor (ET).1, 2 Therefore, little has been written on its prevalence or clinical correlates. The association between IT and disease duration also remains unsettled. This question has pathophysiological implications. Studies have indicated metabolic and structural changes in the ET cerebellum.3, 4 If ET were a disease of progressive cerebellar dysregulation, one would expect more IT in patients with disease of longer duration. We assessed the prevalence and clinical correlates of IT and determined whether there was an association between IT and disease duration.
Synthesis of protein arginine N-methyltransferase 6 inhibitors
Creators: name: Zamiri, Maryam
Publisher: name: University of British Columbia
Year: 2013

description: Protein arginine N-methyltransferases (PRMTs) are pertinent targets for drug discovery as their dysfunction is associated with a number of diseases such as cancers, cardiovascular diseases and viral pathogenesis. The precise role of PRMTs in the initiation, development, or progression of diseases is not known yet. Due to association of PRMT1 and 4 with transcriptional activation, the main focus of inhibitor discovery has been on these two enzymes. On the other hand, the goal of this study is to find a PRMT6 specific inhibitor. PRMT6 methylates DNA polymerase β, histones H3 and H4 and HIV proteins: Rev and Tat. PRMT6 uses S-adenosyl-L-methionine (AdoMet) as the “methyl group” source. AdoMet fits into a distinct conserved binding site in the enzyme, which is located adjacent to the protein substrate/catalytic site such that its S⁺-Me motif is correctly positioned with respect to the substrate arginine nitrogen atom that undergoes methylation. Based on crystallography data for PRMT1, the purine C8 center in AdoMet is in close proximity to the methionine sulfur atom (M166 in PRMT6). As shown by Frankel et al. (Faculty of Pharmaceutical Sciences, UBC), the M166C PRMT6 mutant displays activity. Based upon this observation, we hypothesize that Ado-Met analogues with reactive substituents (e.g., CHO) at C8 position of adenine ring will form a covalent bond with the proximal Cys SH group in M166C PRMT6. This validates our further hypothesize that in appropriately designed analogues, it will be possible to subsequently detach the sugar and amino acid components of Ado-Met to leave the adenine ring component alone bound to the enzyme. This provides a unique opportunity to explore the “fragment based approach in drug discovery” to design PRMT6 specific inhibitors.
Temporal disorder in up-down symmetric systems
Creators: name: Martinez-Garcia, Ricardo
name: Vazquez, Federico
name: Lopez, Cristobal
name: Muñoz, Miguel A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The effect of temporal disorder on systems with up-down Z2 symmetry is studied. In particular, we analyze two well-known families of phase transitions: the Ising and the generalized voter universality classes, and scrutinize the consequences of placing them under fluctuating global conditions. We observe that variability of the control parameter induces in both classes "Temporal Griffiths Phases" (TGP). These recently-uncovered phases are analogous to standard Griffiths Phases appearing in systems with quenched spatial disorder, but where the roles of space and time are exchanged. TGPs are characterized by broad regions in parameter space in which (i) mean first-passage times scale algebraically with system size, and (ii) the system response (e.g. susceptibility) diverges. Our results confirm that TGPs are quite robust and ubiquitous in the presence of temporal disorder. Possible applications of our results to examples in ecology are discussed.
The emerging neuropathology of essential tremor
Creators: name: Louis, Elan D.
name: Vonsattel, Jean Paul
Publisher: name: Columbia University
Year: 2008
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: Essential tremor (ET) is one of the most prevalent neurological disorders. At the same time, it is among the most poorly-understood of these disorders. The underlying anatomical pathology of ET has been elusive until recently. Postmortem studies have begun to display some of the underlying brain changes in patients with this disease. These types of investigations are likely to lead the way to additional insights into the pathophysiology of ET and guide the development of therapies for this common movement disorder.
Peter Marcuse at 80: His Extraordinary Contributions to Progressive Planning
Creators: name: Irazabal Zurita, Clara E.
name: Fainstein, Susan
Publisher: name: Columbia University
Year: 2010
Subjects: City planning
Biography

description: Peter Marcuse is known throughout the world as a leading scholar and
practitioner of progressive planning, but he has also been an outstanding
member of Planners Network since it was founded in 1975. Peter is an attorney, a practicing planner and a teacher of planning. He is truly one of the most multifaceted, committed and productive planners anywhere. As
a devoted planner and educator, he has worked extensively inside and outside academia and government to promote the highest ethical standards for the profession. He has also been a consistent advocate for
social justice. The following review of Peter’s scholarship, teaching excellence and service in the field of planning shows how significant his contributions have been.
Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular Degeneration
Creators: name: Sparrow, Janet R.
name: Duncker, Tobias
Publisher: name: Columbia University
Year: 2014
Subjects: Retina--Diseases
Degeneration (Pathology)
Retinal degeneration--Age factors
Retinal degeneration--Genetic aspects
Lipofuscins
Retinal degeneration
Ophthalmology

description: Genes that increase susceptibility to age-related macular degeneration (AMD) have been identified; however, since many individuals carrying these risk alleles do not develop disease, other contributors are involved. One additional factor, long implicated in the pathogenesis of AMD, is the lipofuscin of retinal pigment epithelium (RPE). The fluorophores that constitute RPE lipofuscin also serve as a source of autofluorescence (AF) that can be imaged by confocal laser ophthalmoscopy. The AF originating from lipofuscin is excited by the delivery of short wavelength (SW) light. A second autofluorescence is emitted from the melanin of RPE (and choroid) upon near-infrared (NIR-AF) excitation. SW-AF imaging is currently used in the clinical management of retinal disorders and the advantages of NIR-AF are increasingly recognized. Here we visit the damaging properties of RPE lipofuscin that could be significant when expressed on a background of genetic susceptibility. To advance interpretations of disease-related patterns of fundus AF in AMD, we also consider the photochemical and spectrophotometric features of the lipofuscin compounds responsible for generating the fluorescence emission.
Scalar products in generalized models with SU(3)-symmetry
Creators: name: Wheeler, M
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a generalized model with SU(3)-invariant R-matrix, and review the nested Bethe Ansatz for constructing eigenvectors of the transfer matrix. A sum formula for the scalar product between generic Bethe vectors, originally obtained by Reshetikhin [11], is discussed. This formula depends on a certain partition function Z(\{λ\},\{μ\}|\{w\},\{v\}), which we evaluate explicitly. In the limit when the variables \{μ\} or \{v\} approach infinity, this object reduces to the domain wall partition function of the six-vertex model Z(\{λ\}|\{w\}). Using this fact, we obtain a new expression for the off-shell scalar product (between a generic Bethe vector and a Bethe eigenvector), in the case when one set of Bethe variables tends to infinity. The expression obtained is a product of determinants, one of which is the Slavnov determinant from SU(2) theory. It extends a result of Caetano [13].
description: 28 pages, 12 figures, greatly lengthened exposition in v3; 2 appendices and extra references added
Action tremor of the legs in essential tremor : prevalence, clinical correlates, and comparison with age-matched controls
Creators: name: Poston, Kathleen L.
name: Rios, Eileen
name: Louis, Elan D.
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine

description: The hallmark feature of essential tremor (ET) is action tremor of the arms. Leg tremor may also occur yet it has not been the central focus of previous studies. Its prevalence has only rarely been reported, its clinical correlates have yet to be explored. Our aims were to report the prevalence and analyze the clinical correlates of leg action tremor in patients with ET and, given the propensity for normal elderly individuals to manifest mild limb tremors, compare the prevalence with that in age-matched controls. Kinetic leg tremor rated ≥1 occurred in 28/63 (44.4%) ET cases and in only 9/63 (14.3%) controls (p < 0.001); moderate leg tremor occurred in 14.3% of cases. Leg tremor severity modestly correlated with disease duration (r = 0.31, p = 0.02). However, the severity and laterality of leg tremor did not correlate with those of arm tremor. The pathophysiological implications of this finding deserve further exploration.
Additional file 1 of Phytopathogenic fungi with potential as biocontrol agents for weeds of importance in crops of Antioquia, Colombia
Creators: name: Mira, Yerly
name: Castañeda, Darío
name: Morales, Juan
name: Patiño, Luis
Publisher: name: figshare
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1. Supplementary information.
title: Ultrasmall Superparamagnetic Iron Oxide Enhanced Peripheral MR Lymphangiography – An Effective Method to Reduce Venous Contrast Contamination through Selective Blood Pool Suppression
Creators: name: Kolokythas, Orpheus
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Oedema
subject: Imaging sequences
subject: Contrast agent-intravenous
subject: MR-Angiography
subject: MR
subject: Lymphography
subject: Veins / Vena cava
subject: Contrast agents
subject: Cardiovascular system

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - To learn about a new modified MR lymphangiography technique of extremities using an intravenous ultrasmall superparamagnetic iron oxide (USPIO) agent in combination with long echo times for blood pool suppression. - To learn about examples and...
Principles of supernova-driven winds
Creators: name: Stringer, M. J.
name: Bower, R. G.
name: Cole, S.
name: Frenk, C. S.
name: Theuns, T.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The formation of galaxies is regulated by a balance between the supply of gas and the rate at which it is ejected. Traditional explanations of gas ejection equate the energy required to escape the galaxy or host halo to an estimate for the energy yield from supernovae. This yield is usually assumed to be a constant fraction of the total available from the supernova, or is derived from the assumption of a consistent momentum yield. By applying these ideas in the context of a cold dark matter cosmogony, we derive a 1st-order analytic connection between these working assumptions and the expected relationship between baryon content and galaxy circular velocity, and find that these quick predictions straddle recent observational estimates. To examine the premises behind these theories in more detail, we then explore their applicability to a set of gasdynamical simulations of idealised galaxies. We show that different premises dominate to differing degrees in the simulated outflow, depending on the mass of the system and the resolution with which it is simulated. Using this study to anticipate the emergent behaviour at arbitrarily high resolution, we motivate more comprehensive analytic model which allows for the range of velocities with which the gas may exit the system, and incorporates both momentum and energy-based constraints on the outflow. Using a trial exit velocity distribution, this is shown to be compatible with the observed baryon fractions in intermediate-mass systems, but implies that current estimates for low-mass systems can not be solely accounted for by supernova winds under commonly-held assumptions.
description: 16 pages, 13 figures. Accepted to MNRAS
Perspectives on Europe :  vol. 40, no. 1 (Spring 2010)
Creators: name: Council For European Studies, Columbia University
Publisher: name: Columbia University
Year: 2010
Subjects: Health
Satisfaction
Progress

description: In this issue of Perspectives we bring you two sets of stimulating contributions. The first set contains essays drawn from the three plenary sessions at the 17th Europeanists conference in April 2010, held in Montreal. The first two essays, by CES Chair Cathie Jo Martin and Axel van den Berg, are based on their commentaries in the plenary, "The Past and Future of Social Solidarity." The next two essays, by Peter Hall and Michèle Lamont, are based on the plenary, "Successful Societies," which was inspired by the eponymous book Successful Societies: How Institutions and Culture Affect Health (Cambridge University Press, 2009). The two essays together present fascinating insights into this project which explored the social conditions for societal success, understood not simply by measures of economic growth but broader indicators of human health and life satisfaction. The second set of contributions in this volume consists of research reports from CES pre-dissertation fellowship recipients. These reports provide intriguing early results on a range of fascinating projects by rising young scholars. Altogether these contributions convey a picture of many key questions about Europe which today occupy scholars across disciplines.