cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Geotechnical investigation of Ivens Shaft in Lisbon
Creators: name: Pedro, Antonio
Publisher: name: Imperial College London
Year: 2013

description: Construction of underground structures in urban areas requires a detailed assessment of the associated movements imposed on adjacent structures and services and in particular of any damage that may be caused. The most efficient way of investigating these issues is through the application of advanced numerical analysis, using for instance the finite element method. However, for a useful analysis to be performed, a high quality ground investigation must be conducted in order to derive the necessary soil parameters for numerical modelling. This thesis focuses particularly on the case study of the Ivens shaft located near to the Baixa-Chiado station of the Lisbon Metro, Portugal. This is an underground structure of a complex shape and significant depth, situated in the centre of the city and it is therefore important to assess the influence of its construction on the existing adjacent structures and services. In the first part of the thesis the results of the geotechnical survey performed on the relevant Miocene formations located at the Ivens shaft site are presented and discussed. In particular, the “Areolas de Estefânia” formation was characterised in detail since this layer had not sustained significant investigation in the past, mainly due to difficulties in sampling. From the extensive characterisation undertaken, which included both field and advanced laboratory tests, it was possible to derive a suitable framework for the different formations in terms of strength and stiffness. Such information was then used to calibrate appropriate soil constitutive models for use in the numerical analyses. In this respect, the new generation of algorithms, known as Genetic Algorithms, was employed to increase the efficiency and accuracy of the calibration procedure. The second part of the thesis focuses on the 3D numerical modelling of the excavation of the Ivens shaft, which was performed employing the state-of-the-art software ICFEP (Imperial College Finite Element Program). The results obtained permitted the quantification of the shaft and ground movements and their effect on adjacent structures. Particular attention was given to the influence of the excavation on the Baixa-Chiado station and on the adjacent buildings founded near the ground surface. Finally, a parametric study was carried out in order to investigate a number of shaft parameters that may affect the movements and to provide more general guidance for shaft construction.
The phenotype and function of CD25+[superscript]CD127-[superscript] regulatory T cells in rheumatoid arthritis
Creators: name: Cribbs, Adam
Publisher: name: Imperial College London
Year: 2013

description: Regulatory T cells control many aspects of the immune system by enforcing dominant negative responses on other immune cells. Defective regulatory T cell function has been linked to many autoimmune diseases, including rheumatoid arthritis. Cytotoxic T lymphocyte antigen 4 (CTLA-4) plays a critical role in the development and function of regulatory T cells. Moreover, CTLA-4 function has been shown to be defective in rheumatoid arthritis; however the exact mechanism by which reduced expression of CTLA-4 leads to an inability of regulatory T cells to suppress effector T cells is still not clear. In this thesis I show that regulatory T cells isolated from peripheral blood of patients with rheumatoid arthritis are unable to suppress the proliferation and IFN-γ cytokine secretion of effector T cells in vitro. This lack of suppression was associated with reduced expression of total and surface CTLA-4. The mechanism underlying this reduction was found to be through methylation of a key CpG in an NFAT binding site within the CTLA-4 promoter. Methylation of this site resulted in reduced NFAT binding, and hence a reduction in CTLA-4 transcription. The observation that epigenetic changes could be responsible, in part, for defective Treg function raises the possibility for therapeutic intervention using methylation inhibitors. CTLA-4 is a known inducer of the immunoregulatory enzyme, indolamine 2,3- dioxygenase (IDO), and in this study it was shown that regulatory T cells from patients with rheumatoid arthritis were unable to induce the expression and enzymatic activity of IDO-1 in co-cultures with antigen presenting cells. CTLA-4 blockade was found to impair the ability of Tregs in co-culture to induce the expression of IDO-1, thereby mimicking the phenotype of a RA Treg. These findings suggest that one of the consequences of the reduced CTLA-4 expression displayed by regulatory T cells in rheumatoid arthritis is a failure to induce IDO expression in antigen presenting cells. This could explain, at least in part, the reduced suppressive capacity of regulatory T cells in rheumatoid arthritis. In addition to CTLA-4, a number of other molecules associated with regulatory T cell suppression such as CREM, CREB, IL-10 and CXCL10 were also found to be dysregulated in regulatory T cells isolated from patients with rheumatoid arthritis. These results suggest that other molecules associated with regulatory T cell suppression may also be epigenetically controlled and provide an insight into the inability of regulatory T cells to maintain immunological homeostasis in patients with RA.
The variability properties of X-ray steep and X-ray flat quasars
Creators: name: Fiore, Fabrizio
name: Laor, Ari
name: Elvis, Martin
name: Nicastro, Fabrizio
name: Giallongo, Emanuele
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have studied the variability of 6 low redshift, radio quiet `PG' quasars on three timescales (days, weeks, and months) using the ROSAT HRI. The quasars were chosen to lie at the two extreme ends of the ROSAT PSPC spectral index distribution and hence of the H$β$ FWHM distribution. The observation strategy has been carefully designed to provide even sampling on these three basic timescales and to provide a uniform sampling among the quasars We have found clear evidence that the X-ray steep, narrow H_beta, quasars systematically show larger amplitude variations than the X-ray flat broad H_beta quasars on timescales from 2 days to 20 days. On longer timescales we do not find significant differences between steep and flat quasars, although the statistics are poorer. We suggest that the above correlation between variability properties and spectral steepness can be explained in a scenario in which the X-ray steep, narrow line objects are in a higher L/L_Edd state with respect to the X-ray flat, broad line objects. We evaluated the power spectrum of PG1440+356 (the brigthest quasar in our sample) between 2E-7 and 1E-3 Hz, where it goes into the noise. The power spectrum is roughly consistent with a 1/f law between 1E-3 and 2E-6 Hz. Below this frequency it flattens significantly.
description: ApJ in press
Development of a breakthrough cancer pain assessment tool
Creators: name: Webber, Katherine
Publisher: name: Imperial College London
Year: 2012

description: Breakthrough cancer pain (BTCP) is a type of pain characterised by transient pain exacerbations on the background of stable and well-controlled pain. It is a significant problem in cancer patients, however, there are no fully validated diagnostic or measurement instruments to identify and assess this type of pain. The aim of this study was to develop and validate a clinical tool to diagnose and quantify BTCP. This study consisted of two stages. Stage one involved the development of a BTCP diagnostic algorithm, which was tested for diagnostic accuracy in 135 cancer patients. The ‘gold-standard’ BTCP diagnostic test for comparison was a comprehensive clinical assessment with a cancer pain expert. The sensitivity of the diagnostic algorithm to detect ‘true cases’ of BTCP was 0.54 (i.e. 54% of expert diagnosed BTCP cases screened positively), specificity 0.78 (78% of non-BTCP patients screened negatively), positive predictive value 0.84 (84% of cases that screened positively had the condition of BTCP), and negative predictive value 0.60 (60% of those that screened negatively did not have the condition). Stage two involved the development of a BTCP measurement instrument from first principles according to international standards. This instrument was then tested on 100 BTCP patients to assess for measurement properties of validity, reliability, responsiveness and acceptability. Reliability testing confirmed that there was an acceptable degree of measurement error. Validity testing confirmed two underlying BTCP dimensions in the instrument. All items and summary scores correlated appropriately with external measures of BTCP. The instrument demonstrated responsiveness by correlating with the patient impression of change and clinical measures of change. In summary, this is the first measurement instrument with robust validity and reliability data for the clinical diagnosis and quantification of BTCP. The measurement instrument met all required standards to recommend its general use however, the diagnostic tool had a lower than expected ability to detect ‘true’ cases of BTCP. The clinical implications of this study mean that once BTCP has been identified the measurement tool could be used to quantify the severity of BTCP, and monitor BTCP experience over time.
Oral history interview with Sadja Greenwood, 2001
Publisher: name: Columbia University
Year: 2019
Subjects: Physicians
Abortion--United States
Abortion
Abortion--Law and legislation--United States
Abortion--History--20th century.--United States
Physicians--Attitudes.--United States
Reproductive rights--United States

description: Early life and family: born in new York, mother's assistance of women in need of illegal abortions in 1920's and 30's, influence of family on career path; education: Radcliff college, where freshman roommate had illegal abortion in 1947; Pre-medical courses at University of Washington; medical school; internship at San Francisco General Hospital; volunteer work at Planned Parenthood; work as general practioner; residency obstetrics/gynecology; personal experience with an illegal abortion; assistance for women in raising money through underground referral network for abortions performed in Mexico and Japan; opened a teen clinic in San Francisco; political activism for abortion law reform; work for International Planned Parenthood Federation in Singapore from 1963-1965; began abortion clinic immediately following Roe v. Wade; descriptions of typical patients from the Haight Ashbury district during the 1960's of worst case, of procedures and technology
Additional file 5: of A novel R2R3-MYB from grape hyacinth, MaMybA, which is different from MaAN2, confers intense and magenta anthocyanin pigmentation in tobacco
Creators: name: Chen, Kaili
name: Du, Lingjuan
name: Liu, Hongli
name: Liu, Yali
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S5. Mass spectrum and structure patterns of cyanidin-3-rutinoside. (DOCX 153 kb)
LRP-1-dependent and -independent endocytic pathways of TIMP-3
Creators: name: Scilabra, Simone Dario
Publisher: name: Imperial College London
Year: 2012

description: Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an endogeneous inhibitor of metalloproteinases (MMPs), adamalysins (ADAMs) and adamalysins with thrombospondin motifs (ADAMTSs), and consequently TIMP-3 is an important regulator of extracellular matrix (ECM) turnover. It has been shown that TIMP-3 levels in the tissue are regulated post-translationally by endocytosis. This study aimed to characterize the mechanism of TIMP-3 endocytosis in more detail. In this thesis, I demonstrated that TIMP-3 is endocytosed and degraded by a number of cell types including chondrocytes, fibroblasts, and monocytes. I found that the endocytic receptor low-density lipoprotein receptor-related protein-1 (LRP-1) plays a major role in TIMP-3 endocytosis. Nevertheless, I found that TIMP-3 can also be internalized by LRP-1-null cells, indicating that an LRP-1-indepentent endocytic pathway also occurs. CHO-cells lacking heparin sulphate proteoglycans (HSPGs) efficiently endocytosed TIMP-3, indicating that HSPGs are not involved in its endocytosis. Shedding of LRP-1 has been shown to reduce cell surface levels of the receptor, and hence to modulate endocytosis of its ligands. I demonstrated that LRP-1 shedding leads to accumulation of soluble LRP-1 (sLRP-1) in the medium of chondrosarcoma cells. sLRP-1 interacted with TIMP-3 and inhibited its endocytosis, but had no effect on TIMP-3 inhibition of target metalloproteinases, indicating that sLRP-1 negatively regulates TIMP-3 endocytosis. TIMP-3 endocytosis was not affected by addition of GM6001, which inhibits interaction with target metalloproteinases, indicating that TIMP-3 can be internalized independently. Internalization of TIMP-3 in complex with a number of metalloproteinases occurred with the same kinetics as that of TIMP-3 alone. Furthermore, TIMP-3 promoted the endocytosis of MMP-1, suggesting that TIMP-3 can mediate the scavenging of metalloproteinases by cells. The study thus identifies LRP-1 as a central mediator of TIMP-3 endocytosis, and indicates that this process regulates levels of TIMP-3 in the ECM, thus contributing to the maintenance of tissue homeostasis.
Elastic and diffractive scattering at the LHC
Creators: name: Khoze, V. A.
name: Martin, A. D.
name: Ryskin, M. G.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Inspired by the new TOTEM data on elastic $pp$ scattering at 13 TeV, we study the possibility to describe all the diffractive collider data ($σ_{\rm tot}, dσ_{\rm el}/dt$, $ρ\equiv$Re$A$/Im$A$, \sd) in a wide interval of energy (0.0625 to 13 TeV) in the framework of a two-channel eikonal model. We show that a satisfactory description can be achieved without an odd-signature (Odderon) exchange contribution. We consider the possible role of the QCD Odderon which may improve the description of $ρ$ and discuss the importance of the odd-signature term if the amplitude were to exceed the black disc limit.
description: 17 pages, 4 figures, version published in Phys. Lett. B
Acarus scabiei Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Acaridae
Acarus
Acarus scabiei

description: Acarus scabiei [spec. nov.]
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 616, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Dimensional Reduction and Non-perturbative generation of magnetic mass in non-abelian gauge theory at finite temperature
Creators: name: Naik, Satchidananda
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: A non-perturbative mass of $0.2719 g^2 T$ is generated for the magnetic sector of the $SU(2)$ gauge theory at high temperature due to the condensation of Polyakov \cite{Pol} monopole and antimonopole which form a magnetic glue ball. String tension for the spatial wilson loop is calculated which is of the same order of magnitude and has same temperature dependence as obtained from lattice simulation.
description: 9 pages, latex file, no figure
title: ESPACIOS Académicos
title: Boletín informativo
titleType: AlternativeTitle
Creators: name: Facultad de Arquitectura y Ciencias del Hábitat
Publisher: name: Zenodo
Year: 2025

description: La gestión académica 2025 marca un hito en la historia de la Facultad de Arquitectura y Ciencias del Hábitat. No solo porque coincide con la conmemoración del Bicentenario de Bolivia, sino porque nos encuentra impulsando una serie de iniciativas orientadas a fortalecer nuestra identidad, proyectar nuestra visión académica y renovar nuestro compromiso con el país.

Este segundo número de Espacios Académicos reúne los primeros pasos de ese nuevo ciclo. Desde la bienvenida a las nuevas generaciones, pasando por la celebración institucional de la EXPO FAyCH 2025, hasta la presentación del logo conmemorativo del Bicentenario y la incorporación de Facundo, nuestra nueva mascota institucional, cada una de estas acciones responde a una pregunta clave: ¿qué tipo de comunidad académica queremos ser?

Queremos una comunidad que enseñe con compromiso y también con afecto, que innove sin olvidar su memoria, que mire el país con ojos críticos, y que sepa construir futuro desde el trabajo colectivo. Este boletín es parte de esa conversación. Porque comunicar lo que hacemos, lo que somos y lo que soñamos, también es parte del proceso de proyectar(nos).
Oral history interview with Sally Falk Moore, 2001
Publisher: name: Columbia University
Year: 2021
Subjects: Women lawyers

description: Childhood: early life in New York City; Barnard College, B.A. 1943, desire for more liberal curriculum; Columbia Law School, LL.B. 1945; political ambitions; member of moot court; encounters with professors; job market for female lawyer; associate attorney at Spence, Hotchkiss, Parker and Duryea; war dept. for Nuremberg Trials; Columbia University, Anthropology Ph.D. 1957; necessity of networking for job ascension; visiting Haiti; Ansley Prize recipient, Columbia University 1957; professor, University of Southern California; studying Chagga people in Africa; Legal Anthropology; professor, Harvard Law School, 1981-present; Dean, Graduate School of Arts and Sciences, 1985-1989
Induced Field Theory on the Brane World - Gravity, Extrinsic Curvature, and Gauge Fields
Creators: name: Akama, Keiichi
name: Hattori, Takashi
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show how the gravity, extrinsic curvature, and gauge field theories are induced on dynamically localized brane world. They should obey the Gauss-Codazzi-Ricci equation in addition to their own equations of motion. As an example, we derive the solitonic solution for curved domain wall in five dimensions in terms of gravity and extrinsic curvature fields of the brane, and then derive the effective action for their field theory on the brane.
description: 5 pages, no figures
High-resolution spectroscopy of single nuclear spins via sequential weak measurements
Creators: name: Pfender, Matthias
name: Wang, Ping
name: Sumiya, Hitoshi
name: Onoda, Shinobu
name: Yang, Wen
name: Dasari, Durga Bhaktavatsala Rao
name: Neumann, Philipp
name: Pan, Xin-Yu
name: Isoya, Junichi
name: Liu, Ren-Bao
name: Wrachtrup, J.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Quantum sensors have recently achieved to detect the magnetic moment of few or single nuclear spins and measure their magnetic resonance (NMR) signal. However, the spectral resolution, a key feature of NMR, has been limited by relaxation of the sensor to a few kHz at room temperature. The spectral resolution of NMR signals from single nuclear spins can be improved by, e.g., using quantum memories, however at the expense of sensitivity. Classical signals on the other hand can be measured with exceptional spectral resolution by using continuous measurement techniques, without compromising sensitivity. To apply these techniques to single-spin NMR, it is critical to overcome the impact of back action inherent of quantum measurements. Here we report sequential weak measurements on a single $^{13}$C nuclear spin. The back-action of repetitive weak measurements causes the spin to undergo a quantum dynamics phase transition from coherent trapping to coherent oscillation. Single-spin NMR at room-temperature with a spectral resolution of 3.8 Hz is achieved. These results enable the use of measurement-correlation schemes for the detection of very weakly coupled single spins.
description: Article: 16 pages, 4 figures Supplementary: 23 pages, 9 figures
An overview of Arup computational fluid dynamics projects
Creators: name: Keenahan, Jennifer
name: MacReamoinn, Reamonn
name: Paduano, Cristina
Publisher: name: figshare
Year: 2020
Subjects: subject: 120302 Design Innovation
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: In recent years, end users have become more concerned with the human experience and the personal comfort of the individual is becoming more important in the design of the built environment. Computational Fluid Dynamics (CFD) is a tool that permits assessment of personal comfort. CFD is a stream of fluid mechanics that utilises numerical methods to analyse and solve problems involving fluid flows. The fundamental basis for these problems are the Navier-Stokes equations. While research applications of CFD are developing, as it the use of CFD in the aerospace industry, the use of CFD in Civil Engineering applications is currently at the cutting edge. Arup have recently developed a team to work on such projects and some of these will be presented in this paper. The paper will discuss the research question of each project, the methodology adopted in developing the models, the results of the simulations and some lessons learned going forward. Based on the projects done to date, it can be concluded that CFD has been shown to be a powerful tool that adds valuable information to fluid flow problems
Acarus farinae Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Acaridae
Acarus
Acarus farinae

description: Acarus farinae [spec. nov.]
Habitat in Farina Europae, Americae.
Inter Sirones Farinae, Scabiei, Dysenteriae, Hemitritaei non reperi alias differentias, quam a loco petitas. Amoen. acad. 3. p: 333.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on pages 616-617, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Simple and accurate method for central spin problems
Creators: name: Lindoy, Lachlan P.
name: Manolopoulos, David E.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We describe a simple quantum mechanical method that can be used to obtain accurate numerical results over long time scales for the spin correlation tensor of an electron spin that is hyperfine coupled to a large number of nuclear spins. This method does not suffer from the statistical errors that accompany a Monte Carlo sampling of the exact eigenstates of the central spin Hamiltonian obtained from the algebraic Bethe ansatz, or from the growth of the truncation error with time in the time-dependent density matrix renormalization group (t-DMRG) approach. As a result, it can be applied to larger central spin problems than the algebraic Bethe ansatz, and for longer times than the t-DMRG algorithm. It is therefore an ideal method to use to solve central spin problems, and we expect that it will also prove useful for a variety of related problems that arise in a number of different research fields.
description: Article: 5 pages, 5 figures Supplementary material: 15 pages, 6 figures
Endothelial cell signalling of APC and thrombin : the involvement of protein kinase C
Creators: name: Yu, Yao
Publisher: name: Imperial College London
Year: 2012

description: Activated protein C (APC) is a natural anticoagulant. In addition to this well-described function, APC also mediates endothelial cell (EC) cytoprotection, including anti-apoptotic, anti-inflammatory and endothelial barrier integrity stabilising effects. APC confers these effects through proteolytic activation of protease activated receptor 1 (PAR1), but only when it is bound to its receptor, endothelial protein C receptor (EPCR). Interestingly, thrombin exerts opposing cellular responses (including induction of endothelial hyperpermeability) through activation of PAR1. How activation of the same receptor can mediate such different signals remains unclear. I hypothesised that, downstream of PAR1 cleavage, activation of different protein kinase C (PKC) isoforms may account for the divergent signal transduction. The aim of my thesis was to explore the contribution of specific PKC isozyme(s) that are involved in APC and thrombin mediated signalling. To do this, I expressed, purified and characterised a panel of APC variants lacking either anticoagulant activity, EPCR binding, PAR1 binding or proteolytic activity. I demonstrated that both APC and thrombin activate Erk1/2 pathway in the endothelial cells in a dose and time-dependent manner. APC also dose-dependently stabilised endothelial monolayer integrity, whereas thrombin disrupted this. APC’s cytoprotective properties, based on this established cell assay model, were found to be PAR1 and EPCR dependent. Using peptides that inhibit specific PKC isozymes, I found that the atypical PKCζ isozyme, was involved in Erk1/2 phosphorylation triggered by thrombin and both classical PKC isozymes (PKCβ1) and PKCζ were involved in the hyperpermeability induced by thrombin. In contrast, no PKC isozyme was found to play roles in the APC-mediated Erk1/2 activation as well as EC permeability reduction. These findings might indicate that the difference in PKC involvement may contribute to the diverse intracellular signalling pathways of APC and thrombin, and hence their opposite cellular responses.
[Poemas – Sobre 11]
Creators: name: Marcos, Ana
name: Ana, Marcos
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Littérature
Poésie

description: - "Dos estampas del campo – Glebas estelares (Tierras de España)" (1 p. numérotée 5 ; img. 001) : Poème en 2 parties numérotées 1-2. Note à la fin du texte : « Perteneciente a mis "Cantos penínsulares", serie "Los campesinos" » 
 - [¿Puede un árbol de hielo y estertores] (2 p. numérotées 5-6 ; img. 001-002),
- [Que hermoso es el corazón] (1 p. numérotée 6 ; img. 002),
- "Nueva defensa de Madrid" (2 p. numérotée 6-7 ; img. 002-003) : Note concernant les les dix premières lignes réunies avec une accolade à droite du texte : "Estas 8 lineas y las dos siguientes son las últimas en vez de las primeras copiadas por error".
- [Sigue. Un paso más hermano. Estamos] (1 p. numérotée 7 ; img. 003),
- [La palabra es semilla desbordante] (1 p. numérotée 8 ; img. 004),
- [Erase un hombre] (1 p. numérotée 8 ; img. 004),
- [Aquí dejo de un clavo mis palabras pendientes] (1 p. numérotée 8 ; img. 004),
- [Era un hombre] (1 p. numérotée 8 ; img. 004),
- [Aquí me quedo yo] (1 p. numérotée 13 ; img. 005),
- [Despierto cada noche y se repite] (1 p. numérotée 13 ; img. 005),
- [Quisiera ser como el tiempo] (2 p. numérotées 13-14 ; img. 005-006),
- [Mirad por dentro al corazón de un preso] (1 p. numérotée 14 ; img. 006).

Les deux dernières pages (numérotées 15-16 ; img. 007-008) contiennent des vers seuls et des strophes indépendantes, séparés par des sauts de lignes : 
- [Yo he vestido el soneto de batalla] (1 p. numérotée 15 ; img. 007),
- [Enmohecida la cadena] (1 p. numérotée 15 ; img. 007),
- [Yo no siento mi pena cuando miro la tuya] (1 p. numérotée 15 ; img. 007),
- [No se tropieza con su mismo ataúd al entrar el atroz cobertizo] (1 p. numérotée 15 ; img. 007),
- [Si he vivido dos vidas he de morir dos muertes (mio)] ] (1 p. numérotée 15 ; img. 007),
- [La estrella en relámpago feroces de los ojos] (1 p. numérotée 15 ; img. 007),
- [Gemebundo (sic)] (1 p. numérotée 15 ; img. 007),
- [Esta ciudad de hierro y de cemento] (1 p. numérotée 15 ; img. 007),
- ["… cada prisión está construida con los ladrillos de la infamia] (1 p. numérotée 15 ; img. 007),
- [Dejar mi alma enredada a tu caballera como deje mis besos] (1 p. numérotée 15 ; img. 007),
- [Las llamas escarlatas de la aurora] (1 p. numérotée 15 ; img. 007),
- [Hay ojos que confunden mis heridas con rosas] (1 p. numérotée 16 ; img. 008),
- [Llamarte] (1 p. numérotée 16 ; img. 008),
- [Cayó y tu corazón resbalaba sonoro] (1 p. numérotée 16 ; img. 008).
description: Notes : Papier blanc très fin dont on voit par transparence l’écriture au verso. Plume noire. Rares corrections au stylo bleu.
description: Source: Num. Ref. : MA-AA-011
description: Source: Localisation du fonds : Archives Marcos Ana. Madrid (Espagne)
description: created: 1939/1961
Additional file 6: of A novel R2R3-MYB from grape hyacinth, MaMybA, which is different from MaAN2, confers intense and magenta anthocyanin pigmentation in tobacco
Creators: name: Chen, Kaili
name: Du, Lingjuan
name: Liu, Hongli
name: Liu, Yali
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: Figure S6. Histological localization of anthocyanins in leaf tissues of the control, OE-MaAN2, and OE-MaMybA tobaccos. The genotypes are the control (a-d), OE-MaAN2 (e-h), and OE-MaMybA (i-l); abaxial epidermis (a, e, and i), trichomes (b, f, and j), cross-sections through leaves (c, g, and k), and leaf veins (d, h, and l). ep, epidermal; hy, hypodermal; tr, trichome; pa, parenchyma; pp., palisade parenchyma; st, stomata; sp., spongy parenchyma; va, vascular bundle. Bars: 100â Îźm. (DOCX 550 kb)
Rubin (2021) When to Adjust Alpha.pdf
Creators: name: Rubin, Mark
Publisher: name: figshare
Year: 2021
Subjects: Survey Results

description: Scientists often adjust their significance threshold (alpha level) during null hypothesis significance testing in order to take into account multiple testing and multiple comparisons. This alpha adjustment has become particularly relevant in the context of the replication crisis in science. The present article considers the conditions in which this alpha adjustment is appropriate and the conditions in which it is inappropriate. A distinction is drawn between three types of multiple testing: disjunction testing, conjunction testing, and individual testing. It is argued that alpha adjustment is only appropriate in the case of disjunction testing, in which at least one test result must be significant in order to reject the associated joint null hypothesis. Alpha adjustment is inappropriate in the case of conjunction testing, in which all relevant results must be significant in order to reject the joint null hypothesis. Alpha adjustment is also inappropriate in the case of individual testing, in which each individual result must be significant in order to reject each associated individual null hypothesis. The conditions under which each of these three types of multiple testing is warranted are examined. It is concluded that researchers should not automatically (mindlessly) assume that alpha adjustment is necessary during multiple testing. Illustrations are provided in relation to joint studywise hypotheses and joint multiway ANOVAwise hypotheses.
Invariant higher-order variational problems: Reduction, geometry and applications
Creators: name: Meier, David
Publisher: name: Imperial College London
Year: 2013

description: This thesis is centred around higher-order invariant variational problems defined on Lie groups. We are mainly motivated by applications in computational anatomy and quantum control, but the general framework is relevant in many other contexts as well. We first develop a higher-order analog of Euler-Poincare reduction theory for variational problems with symmetry and discuss the important examples of Riemannian cubics and their higher-order generalisations. The theory is then applied to higher-order template matching and the optimal curves on the Lie group of transformations are shown to satisfy higher-order Euler-Poincare equations. Motivated by questions of model selection in interpolation problems of computational anatomy, we then study the relationship between Riemannian cubics on manifolds with a group action (`object manifolds') and Riemannian cubics on the corresponding group itself. It is shown, for example, that in Type I symmetric spaces only those Riemannian cubics can be lifted horizontally that lie in flat, totally geodesic submanifolds. We then return to higher-order template matching and provide an alternative derivation of the Euler-Lagrange equations using Lagrange multipliers, which leads to a geometric interpretation of the equations in terms of higher-order Legendre-Ostrogradsky momenta. Building on this approach, we develop a variational integrator that respects the geometric properties of continuous-time solution curves. We also derive the corresponding adjoint equations. The remainder of the thesis is concerned with an application to quantum control, namely, to the problem of experimentally steering a quantum system through a series of target states at prescribed times. We show that the Euler-Lagrange equations lead to Riemannian cubic splines on the special unitary group, under whose action the system evolves optimally. Finally, we perform numerical experiments for two-level quantum systems and extend the formalism to the control of coherent states in bosonic multi-particle systems.
Scanning DMA data analysis II. Integrated DMA-CPC instrument response and data inversion
Creators: name: Huajun Mai
name: Weimeng Kong
name: Seinfeld, John H.
name: Flagan, Richard C.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Analysis of scanning electrical mobility spectrometer (SEMS) or SMPS data requires coupling the scanning differential mobility analyzer (DMA) transfer function with the response functions for the instrument plumbing and the detector. In the limit of plug flow (uniform velocity) within the DMA, the scanning DMA transfer function has the same form as that for constant voltage. Most SEMS/SMPS data analysis uses this model, though previous studies have shown that boundary layers distort the transfer function during scanning DMA measurements. Part I determined the instantaneous transfer function during scanning of the TSI Model 3081 A long column DMA by modeling the flows, fields, and particle trajectories within the actual DMA geometry. This study (Part II) combines that transfer function with empirical data on the efficiencies and delay time distributions of the plumbing and detector of the SEMS/SMPS to determine the instantaneous rate at which particles are counted, and integrates the count rate over the finite counting time interval to obtain the integrated SEMS/SMPS response function. Simulations using this geometrical model are compared with those obtained using traditional, idealized DMA models for scan rates ranging from slow (240 s) to very fast (10 s), and with measurements of monodisperse calibration aerosols. Data inversion studies show that both increasing and decreasing voltage scans can be used to determine the particle size distribution, even with fast scans. Copyright © 2018 American Association for Aerosol Research
The Development of a Heat Assisted Section Rolling Process for Strip
Creators: name: Sidek, Mohd Zaidi
Publisher: name: Imperial College London
Year: 2012

description: This research aims to examine the feasibility of a new concept in section rolling of thick strip, which either could not be rolled at present due to cracking at bent corners. Whereas, the second moment of area of sections could be increased through sharpened corners and increased gauge thickness. A heat assisted section rolling process is proposed. This process is based on application of high intensity heat on the inner surface of the strip, immediately prior to rolling. To investigate the new section rolling concept, the following work has been carried out. Firstly, the material property of the S450 steel has been determined using the Gleeble simulator, followed by thermal conductivity tests. Since a freon was used to increase temperature gradient, the heat transfer coefficient for the freon-hot surface interaction was determined. Finally, the four point hot bending tests were conducted to validate the simulation model. For this purpose, a hot bending test rig was designed and fabricated, utilizing an halogen heater as the heat source. The results between experiment and simulation were compared and a good correlation was found. Then, finite element analyses of a single pass hot rolling process has been adopted to investigate the neutral axis shift and section thickening effects. It is revealed that localised heating creates bulging on the compressed surface. The bulged surface affects the both neutral axis and thickening of the formed parts. This research has demonstrated that localised heating has a potential to be employed in section rolling operations. It shows that the neutral axis of the bent region shifted closer to the tensile surface would reduce the tendency for surface cracking. In addition, the increase in thickness that arises at a bend would enhance the stiffness of rolled sections. Ultimately a process window for heat assisted section rolling has been established.
Additional file 1 of An assessment of the role of socio-economic, maternal and service utilization factors in increasing self-reported maternal complications in India
Creators: name: Kumar, Pradeep
name: Srivastava, Shobhit
name: Maurya, Chanda
name: Dhillon, Preeti
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: Additional file 1. Percentage distribution of background characteristics for women in India, 2005-06 and 2015-16.
Sequent Calculi with Context Restrictions and Applications to Conditional Logic
Creators: name: Lellmann, Björn
Publisher: name: Imperial College London
Year: 2013

description: In this thesis we consider generic tools and techniques for the proof-theoretic investigation of not necessarily normal modal logics based on minimal, intuitionistic or classical propositional logic. The underlying framework is that of ordinary symmetric or asymmetric two-sided sequent calculi without additional structural connectives, and the point of interest are the logical rules in such a system. We introduce the format of a sequent rule with context restrictions and the slightly weaker format of a shallow rule. The format of a rule with context restrictions is expressive enough to capture most normal modal logics in the S5 cube, standard systems for minimal, intuitionistic and classical propositional logic and a wide variety of non-normal modal logics. For systems given by such rules we provide sufficient criteria for cut elimination and decidability together with generic complexity results. We also explore the expressivity of such systems with the cut rule in terms of axioms in a Hilbert-style system by exhibiting a corresponding syntactically defined class of axioms along with automatic translations between axioms and rules. This enables us to show a number of limitative results concerning amongst others the modal logic S5. As a step towards a generic construction of cut free and tractable sequent calculi we then introduce the notion of cut trees as representations of rules constructed by absorbing cuts. With certain limitations this allows the automatic construction of a cut free and tractable sequent system from a finite number of rules. For cases where such a system is to be constructed by hand we introduce a graphical representation of rules with context restrictions which simplifies this process. Finally, we apply the developed tools and techniques and construct new cut free sequent systems for a number of Lewis’ conditional logics extending the logic V. The systems yield purely syntactic decision procedures of optimal complexity and proofs of the Craig interpolation property for the logics at hand.
On the variability of the solar mean magnetic field: contributions from various magnetic features on the surface of the Sun
Creators: name: Bose, Souvik
name: Nagaraju, K.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The solar mean magnetic field (SMMF) is referred to as the disc-averaged line-of-sight (LOS) magnetic field that also reflects the polarity imbalance of the magnetic field on the Sun. The origin of the SMMF has been debated over the past few decades, with one school of thought suggesting that the contribution to the SMMF is mostly due to the large scale magnetic field structure, also termed as the background magnetic field, whereas other and more recent studies have indicated that active regions have a major contribution to the observed SMMF. In this paper, we re-investigate the issue of the origin of the SMMF by decomposing the solar disk into plages, networks, sunspots and background regions, thereby calculating the variation in the observed SMMF due to each of these features. We have used full disk images from SDO/{\it AIA} recorded at 1600~Å\, for earmarking plages, networks and background regions and 4500~Å\, images for separating the sunspots. The LOS fields corresponding to each of these regions are estimated from the co-temporal SDO/{\it HMI} full disk magnetograms. The temporal variation of the SMMF shows a near one-to-one correspondence with that of the background field regions suggesting that they constitute the major component of the observed SMMF. A linear regression analysis based on the coefficient of determination shows that the background field dominates, and accounts for 89\% of the variation in the SMMF whereas the magnetic field from the other features accounts for the rest 11\%.
description: Published in the Astrophysical Journal
The Expected Rate of Gamma-Ray Burst Afterglows In Supernova Searches
Creators: name: Woods, Eric
name: Loeb, Abraham
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We predict the rate at which Gamma-Ray Burst (GRB) afterglows should be detected in supernova searches as a function of limiting flux. Although GRB afterglows are rarer than supernovae, they are detectable at greater distances because of their higher intrinsic luminosity. Assuming that GRBs trace the cosmic star formation history and that every GRB gives rise to a bright afterglow, we find that the average detection rate of supernovae and afterglows should be comparable at limiting magnitudes brighter than K=18. The actual rate of afterglows is expected to be somewhat lower since only a fraction of all gamma-ray selected GRBs were observed to have associated afterglows. However, the rate could also be higher if the initial gamma-ray emission from GRB sources is more beamed than their late afterglow emission. Hence, current and future supernova searches can place strong constraints on the afterglow appearance fraction and the initial beaming angle of GRB sources.
description: 13 pages, submitted to ApJL
title: Movilidad Social: Aportes Desde la Educación Superior Técnico-Profesional
title: SERIE ANÁLISIS DE POLÍTICA PÚBLICA: EDUCACIÓN SUPERIOR Nº 1
titleType: Subtitle
Creators: name: Venegas-Muggli, Juan I.
name: Flores Vásquez, Felipe
name: Muñoz, Karla
name: Zuñiga, Diego
name: Valenzuela, Pablo
Publisher: name: INACAP
Year: 2023

description: El siguiente documento analizó el aporte del Subsistema Técnico-Profesional (TP) en la promoción de la movilidad social ascendente. Comprendiendo la movilidad social como la variación de la posición de una persona o familia en una estructura social jerárquica, se aplicaron diferentes metodologías de tipo cuantitativo para examinar el aporte de la educación TP tanto en la movilidad de ingresos o socioeconómica como en la movilidad educativa. Específicamente, se aplicaron tres metodologías: a) análisis de movilidad educativa de sistema educativo general con base en análisis de cohorte de generación que en 2012 se encontraba en segundo medio, b) análisis del beneficio económico de estudiar en la Educación Superior y de entrar al mercado laboral luego de egresar de la Educación Media, c) análisis de movilidad socioeconómica de titulados de INACAP. Los resultados muestran que la Educación Superior Técnico Profesional (ESTP) promueve una mayor movilidad educativa que la Educación Universitaria, al formar una gran proporción de estudiantes de primera generación en Educación Superior. Asimismo, se evidencia que la ESTP es una alternativa real que permite transformar, en un corto período, las condiciones materiales de existencia de miles de personas. Por último, se evidencia que una alta proporción de titulados de INACAP mejoran su nivel socioeconómico tras el paso por la institución.
Monte Carlo simulations of 4d simplicial quantum gravity
Creators: name: Bruegmann, B.
name: Marinari, E.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Dynamical triangulations of four-dimensional Euclidean quantum gravity give rise to an interesting, numerically accessible model of quantum gravity. We give a simple introduction to the model and discuss two particularly important issues. One is that contrary to recent claims there is strong analytical and numerical evidence for the existence of an exponential bound that makes the partition function well-defined. The other is that there may be an ambiguity in the choice of the measure of the discrete model which could even lead to the existence of different universality classes.
description: 16 pages, LaTeX, epsf, 4 uuencoded figures; contribution to the JMP special issue on "Quantum Geometry and Diffeomorphism-Invariant Quantum Field Theory"