cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Design and development of liquid crystal lenses
Creators: name: Ashraf, Mujahid Al Islam
Publisher: name: Swinburne
Year: 2024

description: The use of optics in the fields of nano-technology, telecommunication and medicine has been growing exponentially in recent years. Application of liquid crystals within optics has been a growing trend from flat screen displays to variable focus lenses in a digital versatile discs. One area of the recent developments within optics has been the development of two-photon fluorescence microscopy and high-density three-dimensional optical data storage. In such applications, where a light beam has to be focused deep within the volume of bulk media, aberrations are introduced. The most dominant aberration is spherical aberration which results from the mismatch in refractive indices of the immersion and recording media. The aim of this thesis is to design a liquid crystal lens for dynamic tube length compensation of the spherical aberration. Liquid crystal phase plates are used in everyday liquid crystal displays (LCDs) such as mobile phones and calculators. The technologies required to manufacture a liquid crystal phase plate are well understood. However, an application like three-dimensional data storage requires different properties in the liquid crystal phase plate, which are investigated in this thesis. To fabricate our liquid crystal phase plate we used ZLI-5049-000 from MERCK as the liquid crystal medium, with poly-vinyl alcohol (PVA) and Indium Tin Oxide (ITO) providing the insulating and conducting layers, respectively. It has been demonstrated that vacuum vapour deposition can be used to coat a glass substrate with ITO. However, in order for the ITO coating to be conductive a method is developed where the substrate is heated to 300oC before, during and after the coating. Similarly, a method has been developed for producing a uniform 10
How to arrange follow-up time-intervals for longitudinal brain MRI studies in neurodegenerative diseases
Creators: name: Müller, Hans-Peter
name: Behler, Anna
name: Landwehrmeyer, G. Bernhard
name: Huppertz, Hans-Jürgen
name: Kassubek, Jan
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Time-interval
subject: Linear fit
subject: DDC 150 / Psychology
subject: Magnetic resonance imaging
subject: Brain mapping
subject: Regression analysis
subject: Longitudinal studies
subject: Kernspintomografie
subject: Gehirn
subject: Regressionsanalyse
subject: Längsschnittuntersuchung

description: BackgroundLongitudinal brain MRI monitoring in neurodegeneration potentially provides substantial insights into the temporal dynamics of the underlying biological process, but is time- and cost-intensive and may be a burden to patients with disabling neurological diseases. Thus, the conceptualization of follow-up time-intervals in longitudinal MRI studies is an essential challenge and substantial for the results. The objective of this work is to discuss the association of time-intervals and the results of longitudinal trends in the frequently used design of one baseline and two follow-up scans. MethodsDifferent analytical approaches for calculating the linear trend of longitudinal parameters were studied in simulations including their performance of dealing with outliers; these simulations were based on the longitudinal striatum atrophy in MRI data of Huntington’s disease patients, detected by atlas-based volumetry (ABV). ResultsFor the design of one baseline and two follow-up visits, the simulations with outliers revealed optimum results for identical time-intervals between baseline and follow-up scans. However, identical time-intervals between the three acquisitions lead to the paradox that, depending on the fit method, the first follow-up scan results do not influence the final results of a linear trend analysis. ConclusionsThis theoretical study analyses how the design of longitudinal imaging studies with one baseline and two follow-up visits influences the results. Suggestions for the analysis of longitudinal trends are provided.
Open Science at NWO
Creators: name: Jonge, Hans de
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: open access
open science
NWO
Research funding

description: doi:10.5281/ZENODO.4710935
description: Presentation held at the University of Groningen Grant Week on April 22 2021 about the various ways the Dutch Research Council NWO fosters open science. The following topics are covered: why NWO is committed to open science and what requirements are in place; what NWO does to change incentives and rewards for researchers who engage in open research practices; how NWO support open infrastructures.
Adverse reactions to sulfamethoxazole in HIV seropositive patients, immune aspects.
Creators: name: Daftarian, Mohammad Pirouz.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Health Sciences, Pharmacology.

description: Adverse reactions to sulfonamides were initially described more than 50 years ago. It is not yet clear whether these side effects are due to immunological reactions or drug toxicity. More than 50% of AIDS patients develop adverse reactions to sulfamethoxazole, a sulfonamide drug commonly used for the treatment of infections in these individuals. In order to study the possible role of the humoral immune response in adverse reactions to SMX in HIV-seropositive patients, I designed an ELISA to determine the classes, subclasses and the quantities of the immunoglobulins directed against SMX. Twenty eight HIV-seropositive individuals with a history of adverse reactions to SMX, 20 HIV-seropositive individuals with no such history, and 39 healthy infants and adults were evaluated for the presence of anti-SMX antibodies. To evaluate the cellular immune response in vitro, lymphocyte proliferation assays were performed in the presence of SMX or structurally related compounds. The lymphocytes from HIV-seropositive patients did not proliferate or produce antibody when incubated with these compounds. Only one immunocompetent individual who had a known hypersensitivity to SMX demonstrated high lymphocyte proliferation to SMX-PLL, but not to structurally related compounds. The mechanism of the development of side effects to SMX is complex, and likely involves both toxic and immunologic events. It may be that high blood levels of SMX may lead to an immune response which produces symptoms only when specific antibody levels have exceeded a certain threshold. The detection of antibodies to SMX may be useful in predicting and managing the adverse reactions to this compound in HIV-seropositive individuals. (Abstract shortened by UMI.)
MPEC 2024-K121 : 2024 KW
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 KW

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
GSK3β and CREB3 Gene Expression Profiling in Benign and Malignant Salivary Gland Tumors
Creators: name: Ghahhari, Nastaran Mohammadi
name: Ghahhari, Hamed Mohammadi
name: Kadivar, Mehdi
Publisher: name: the Pasteur Institute of Iran
Year: 1996
Subjects: subject: Basic Sciences

description: Iranian Biomedical Journal (IBJ); ISSN 1028-852X
Supplementary document for Enhancement and optical control of ultrafast THz conductivity in MoSe2MoS2 vertical heterostructure. - 4997387.pdf
Creators: name: Kumar, Sunil
name: Singh, Arvind
name: Nivedan, Anand
name: Kumar, Sandeep
name: Tondusson, Marc
name: Degert, Jérôme
name: oberle, jean
name: YUN, SEOK JOON
name: Lee, Young Hee
name: FREYSZ, Eric
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplemantary information
Bettwanzenbefall in der Wohnung - Was tun?
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Bettwanze
subject: Schädlingsbefall
subject: Faltblatt
subject: Flyer
subject: Tipps
subject: Chemikalien
subject: Gesundheit

description: Sie sind etwa 1 bis 8 Millimeter groß, wohnen in Betten, Bilderrahmen oder hinter Lichtschalterabdeckungen und kommen nachts, um Blut zu saugen. Bettwanzen breiten sich in deutschen Wohnungen immer mehr aus. Sie werden vom Hotelurlaub im Reisegepäck mit nachhause genommen oder verstecken sich in gebraucht gekauften Möbelstücken. Die Stiche sind nicht nur lästig: Hat man die Plagegeister erst einmal in die eigene Wohnung eingeschleppt, sind sie nur schwer wieder loszuwerden. Wie Sie einen Befall erkennen und einen professionellen Schädlingsbekämpfer bei seiner Arbeit unterstützen können, erklärt dieses Faltblatt.
A simulation study of tooling effects in automated manufacturing.
Creators: name: Amini Vadeghani, Siros.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Engineering, Industrial.

description: With advent of complex and expensive automated manufacturing systems tool management is becoming an important issue both in design and implementation phases. The use of highly automated technology has resulted in an increasing need to integrate tool management more thoroughly into other planning and operational issues of these systems. In this research effort a discrete events simulation model has been developed to analyze the system performance under different operational strategies. These strategies include three tool configurations; identical, nonidentical and hybrid, and two part loading patterns; batch and random loading. In addition, a new tool refilling concept, tool replenishing, is also examined. The replenishing concept consists of two policies; preventive and failure replenishing. The effects of shared and dedicated tooling policies have also been investigated. With the comparison of performance measures for each set of operational strategies, the mutual advantages and concerns of each of them are highlighted. Within the simulation scope, the shared tooling policy is significantly superior to the dedicated tooling policy. It is also shown that identical tool configuration outperforms the other tool configurations. These have been confirmed by statistical tests performed on the simulation results.
No Better Time to Practice Open Science Than Now
Creators: name: Sefoga, Akligoh Harry
Publisher: name: Forschungzentrum Jülich
Year: 2020
Subjects: Open Science, Open Science Hardware, COVID-19, AfricaOSH

description: doi:10.5281/ZENODO.3878540
description: This is a guest speaker presentation given at the virtual Open Science Fellows Program 2020 in Berlin. The presentation captures the speakers perspectives on Open Science where he related it to the story of William Kamkwamba from Malawi, his journey through Open Science and Projects and Initiatives that are making use of Open Science in overcoming the challenges of COVID-19 today.
International transference of lean production systems: managerial lessons from Toyota transplants in the USA, Australia, and India
Creators: name: James, Reynold Peter
Publisher: name: Swinburne
Year: 2024

description: The purpose of this thesis is to analyse how Toyota went about the process of transplanting its lean production system into three heavily unionized environments in the USA, Australia, and India, namely NUMMI (New United Motor Manufacturing Inc), TMCA (Toyota Motor Corporation of Australia), and TKM (Toyota Kirloskar Motors). Two research questions are embedded within this broad purpose, namely, what resistance did Toyota meet when attempting to transplant its production system into each of these three countries, and what strategies did it employ to manage this resistance? Toyota generally tries to avoid extremely pluralistic-unionised environments when choosing transplantation sites across the world. Its organisational culture is strongly aligned with a unitarist approach in which its operations are conducted within a family-like atmosphere. Therefore, how Toyota conducts its operations in circumstances dissimilar to this is of considerable interest. In this respect, the research conducted in this thesis provides an additional and unique aspect to the literature. The thesis takes a qualitative, emergent approach to addressing this research purpose and research questions, employing the methodology of conceptual ordering within a framework of a comparative case study analysis. The thesis identifies three distinct models of the transplantation process pursued by each of the Toyota transplants: hybrid (NUMMI), slow and piecemeal (TMCA), and authoritarian (TKM). Within the context of these three processes the thesis identifies five comparison features which characterise the transplantation pathways of the Toyota transplants – industrial peace, the extent and pace of TPS introduction, teamworking. cultural consonance, and organisational learning. By identifying these five comparison features the thesis then analyses why each of the transplants has attained different levels of success in achieving each of these features (for instance, industrial peace) within the context of their respective transplantation processes. The thesis has implications for understanding the forms of resistance, and the strategies to be adopted in managing such resistance, when organisations employing lean manufacturing techniques (such as Toyota) attempt to transplant these techniques across national borders into heavily pluralistic and unionised environments.
Validated Recursion Model of Pi from Holon Coherence Dynamics
Creators: name: Borsinger, L.
Publisher: name: Zenodo
Year: 2025

description: This paper validates a non-geometric derivation of \pi through recursive coherence dynamics in the Holon field framework. Using log–log regression, spinor feedback Lagrangians, and curved vacuum simulations, it confirms that \pi emerges as a phase locking boundary and resonance stability constant rather than a geometric artifact. The results demonstrate that coherence structure alone can define universal constants, supporting a broader shift toward structural unification in physics
Reflections on the evaluation of open science
Creators: name: Peters, Isabella
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: open science
research assessment
responsible metrics
evaluation
indicators
metrics

description: doi:10.5281/ZENODO.5599401
description: Talk presented at the first online Open Science Retreat (https://openscienceretreat.zbw.eu/) organized by ZBW leibniz Information Center for Ecnomics. In this talk four provocations on the state of open science evaluation and open science indicators are discussed.
Enhanced position verification for VANETs using subjective logic
Creators: name: Van Der Heijden, Rens W.
name: Kargl, Frank
name: Al-Momani, Ala'a
name: Abu-Sharkh, Osama M. F.
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Misbehavior detection
subject: Subjective logic
subject: Intrusion detection
subject: Security
subject: DDC 000 / Computer science, information & general works
subject: Vehicular ad hoc networks (Computer networks)
subject: Intrusion detection systems (Computer security)
subject: VANET
subject: Computersicherheit
subject: Eindringerkennung

description: The integrity of messages in vehicular ad-hoc networks has been extensively studied by the research community, resulting in the IEEE 1609.2 standard, which provides typical integrity guarantees. However, the correctness of message contents is still one of the main challenges of applying dependable and secure vehicular ad-hoc networks. One important use case is the validity of position information contained in messages: position verification mechanisms have been proposed in the literature to provide this functionality. A more general approach to validate such information is by applying misbehavior detection mechanisms. In this paper, we consider misbehavior detection by enhancing two position verification mechanisms and fusing their results in a generalized framework using subjective logic. We conduct extensive simulations using VEINS to study the impact of traffic density, as well as several types of attackers and fractions of attackers on our mechanisms. The obtained results show the proposed framework can validate position information as effectively as existing approaches in the literature, without tailoring the framework specifically for this use case.
description: Correction: revised the way an opinion is created with eART, and re-did the experiments (uploaded at arxiv as correction in agreement with TPC Chairs).
Extracting Relevant Points of Interest from Open Street Map to Support E-Mobility Infrastructure Models
Creators: name: Valdes, Javier
name: Wuth, Jane
name: Zink, Roland
name: Schröck, Sebastian
name: Schmidbauer, Matthias
Publisher: name: Bavarian Journal of Applied Sciences
Year: 2018

description: Bavarian Journal of Applied Sciences, 4 (2018), 323-341
description: Bavarian Journal of Applied Sciences, 4 (2018), 323-341
title: System zur automatisierten Messung der Kantenverrundung von Blechbauteilen mit Mehrachs-Kinematik und Laserscanner
Creators: name: Charton, Louis
Publisher: name: UNSPECIFIED
Year: 2024

description: Das Verrunden von Werkstückkanten ist ein wichtiger Fertigungsschritt zur Einhaltung von Normen
und individuellen Spezifikationen. Scharfe Kanten und Grate entstehen in der Regel durch Trennverfahren. Derzeit werden die Kantenradien bei komplexen Bauteilgeometrien jedoch manuell vermessen, eine Automatisierung ist in der Regel nicht vorhanden.
Im Rahmen dieser Arbeit wird ein Demonstrator-System entwickelt, das die Kantenverrundung von
Blechbauteilen mit einem Linienprofil-Laserscanner misst. Der Scanner ist auf einer Vierachs-Kinematik mit SPS montiert, welche Punkte in einem definierten Messbereich anfahren kann. Diese
Punkte werden zuvor anhand einer CAD-Referenzdatei festgelegt. Die Erfassung des in einem Messbereich frei positionierten Blechbauteils erfolgt durch eine einzelne Kamera. Aus dem Kamerabild
wird die Position des Blechbauteils ermittelt und die Bahnkoordinaten für die Kinematik/SPS berechnet. Zusätzlich wird der Demonstrator konstruiert und so gestaltet, dass er im Anschluss an die Thesis
aufgebaut und genutzt werden kann.
Dazu wird ein Python-Programm entwickelt, welches die Kommunikation mit einem Laserscanner,
einer SPS und einer Kamera über Ethernet implementiert. Der Schwerpunkt der praktischen Entwicklung liegt softwareseitig auf der Bildverarbeitung. In diesem Rahmen wird ein neuer Ansatz
entwickelt, um perspektivisch bedingte Verzerrungen aus den Kamerabildern zu entfernen, um anschließend mittels Machine Vision Koordinaten für Messpunkte zu ermitteln. Als Ausgangspunkt
dient die Open-Source-Bibliothek OpenCV. Die festgelegten Messpunkte werden über das Siemens
S7 Protokoll an eine Siemens SPS exportiert.
Abschließende Tests zeigen, dass die durch das Programm berechneten und von der SPS angefahrenen Messpunktkoordinaten bei ausreichender algorithmischer Kalibrierung der Kamera um weniger
als 0,5 mm von den tatsächlichen Koordinaten abweichen können
Validation of the TRISS model of survival in blunt trauma patients using the Ontario Trauma Registry.
Creators: name: Garber, Bryan G.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Health Sciences, Medicine and Surgery.

description: Objective. To compare outcomes in blunt trauma by using Trauma and Injury Severity Score (TRISS) models derived from the Major Trauma Outcome Study (MTOS) and the Ontario Trauma Registry as well as to evaluate the role of the Revised Trauma Score (RTS) within the TRISS model. Methods. Consecutive blunt trauma cases from 11 Level I trauma centres over a 4-year period were identified from the OTR. Coefficients of the Revised Trauma Score were modified using the Ontario data and this score's ability to predict mortality was compared to the Revised Trauma Score derived from MTOS. Two Ontario-specific TRISS models were developed with revised coefficients. The first used the standard Revised Trauma Score and the second used the Revised Score with regenerated coefficients. An expanded TRISS model was developed using all the component variables of TRISS and the Revised Trauma Score using forward step-wise logistic regression analysis. The accuracy of mortality predictions for all models were assessed using a Hosmer-Lemeshow Goodness of Fit statistic as well as by estimating sensitivity, specificity (using probability of survival cutpoint of 50%) and the area under the receiver operating characteristic (ROC) curve. (Abstract shortened by UMI.)
The conception of the Hegelian dialectic.
Creators: name: Brouwer, James.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Philosophy.

description: In its simplest form, this thesis is an attempt to clarify, interpret and defend the nature of the Hegelian dialectic--especially as it is articulated in the Science of Logic. This thesis does not ally itself with any picture of the dialectic as a constraining, oppressive structure, rather it suggests that the dialectic be read more as a dynamic process; an open-ended movement that has, in a certain sense, already anticipated and accounted for many of the objections brought against it.
Open Science and FAIR research data - Presentation for UiB EPISTAT 23/03/2022
Creators: name: Ostrop, Jenny
Publisher: name: Forschungzentrum Jülich
Year: 2022
Subjects: Open Science
Open Data
FAIR Data
FAIR
FAIR4RS
Research Data Management
Library

description: doi:10.5281/ZENODO.6378865
description: Open Science and FAIR research data - Presentation slides for Wednesday seminar at EPISTAT , University of Bergen, 23.03.2022. Open Science UiB Policy for Open Science Open & FAIR research data Data management during the research data life cycle
Thermal conductivity of Papua New Guinea balsa wood measured using the needle probe procedure
Creators: name: Kotlarewski, Nathan James
name: Ozarska, Barbara
name: Gusamo, Benson K.
Publisher: name: Swinburne
Year: 2024

description: A study was undertaken with the aim to determine thermal properties of balsa wood grown in plantations in Papua New Guinea. Thermal conductivity values were measured using the needle probe procedure according to ASTM D5334 (2008). The mean thermal conductivity results of balsa were in the range of 0.0381 W/mK to 0.0665 W/mK, similar to other materials currently used as insulators in the construction industry. A balsa sample with a density of 113 kg m3 had the lowest thermal conductivity value, 0.0339 W/mK, across the tangential and radial wood grain directions. Balsa is exported from Papua New Guinea mostly as end-grain panels to international markets to optimise its strength properties in the axial direction for applications that are exposed to compressive forces. This study revealed that there is the opportunity for Papua New Guinea balsa processors to consider producing perpendicular-grain panels for insulation markets, as the mean thermal conductivity values in this direction can be as low as 0.0381 W/mK, which is much lower than the thermal conductivity of the current end-grain panels at 0.0665 W/mK. The finding creates a potential design opportunity for balsa processors to consider entering new commercial markets to promote Papua New Guinea-grown balsa.
Opening the Research Process: From Publications to Data, and Back Again
Creators: name: Leonelli, Sabina
Publisher: name: Forschungzentrum Jülich
Year: 2020

description: doi:10.5281/ZENODO.4045738
description: I reflect on the impact of Open Science on all stages of the research process, paying particular attention to the practical obstacles standing in the way of Open Science implementation within and across research domains. My discussion is grounded on (1) qualitative empirical studies on whether and how researchers from different disciplines and regions are practicing Open Science; (2) collaborations with infrastructures, repositories and institutions devoted to Open Science implementation; and (3) consultations with the European Commission and various national governments on how research evaluation should be conducted in order to incentivise responsible and sustainable forms of Open Science.
Reading Beyond the Last Page: Understandings of Teachers' Experiences in Book Clubs and Pedagogical Links
Creators: name: Rottmann, Jennifer
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Literacy education
Book club
Reading pedagogy

description: The study explores teachers’ experiences in book clubs and how these experiences inform their pedagogical practices. Framed by a social constructivist epistemological stance, grounded in the work of narrative inquiry, and conceptualized by transactional reader-response theory, this study explores why teachers join and sustain book club membership, the ways books clubs are used to create meaning, how participating in a book club influences pedagogical practices, and ways in which clubs are used to negotiate aspects of their teaching identities and subjectivities. Through a multifaceted qualitative research design, I worked with thirteen teachers who belong to (or have recently belonged to) a book club as a separate entity from their teaching lives. I conducted interviews with thirteen teachers; attended three meetings of three separate book clubs to contextualize the study; and administered written reading profiles to explore participants’ reading practices. This research argues that teachers join and remain in book clubs for social interaction, intellectual stimulation and motivation to read ‘quality’ literature. Knowledges are created and validated by a community of readers capable of such recognition in a forum that does not otherwise exist. Club meetings are used in different and complex ways to negotiate teaching subjectivities and push back against fixed notions of the teacher identity. Further, this study showcases a myriad of ways that teachers’ experiences in book clubs enter the classroom both explicitly and implicitly.
YFR016c/Aip5 is part of an actin nucleation complex in yeast
Creators: name: Glomb, Oliver
name: Bareis, Lara
name: Johnsson, Nils
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Polar growth
subject: Protein interaction network
subject: Formins
subject: Nucleation-promoting factor
subject: Split-ubiquitin
subject: DDC 570 / Life sciences
subject: Protein-protein interactions
subject: Actin
subject: Yeast

description: The polarisome comprises a network of proteins that organizes polar growth in yeast and filamentous fungi. The yeast formin Bni1 and the actin nucleation-promoting factor Bud6 are subunits of the polarisome that together catalyze the formation of actin cables below the tip of yeast cells. We identified YFR016c (Aip5) as an interaction partner of Bud6 and the polarisome scaffold Spa2. Yeast cells lacking Aip5 display a reduced number of actin cables. Aip5 binds with its N-terminal region to Spa2 and with its C-terminal region to Bud6. Both interactions collaborate to localize Aip5 at bud tip and neck, and are required to stimulate the formation of actin cables. Our experiments characterize Aip5 as a novel subunit of a complex that regulates the number of actin filaments at sites of polar growth.
Effects of Acute and Sustained Administration of Vilazodone (EMD68843) on Monoaminergic Systems: An In Vivo Electrophysiological Study
Creators: name: Crnic, Agnes
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Vilazodone
Electrophysiology

description: Vilazodone is a partial 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor (SSRI). Acute administration caused a dose-dependent decrease in dorsal raphe (DR) serotonin (5-HT) neuron firing rates. Vilazodone significantly decreased DR 5-HT neuronal firing following 2-day administration, which was shown to recover completely after 14-day administration. The 2-day administration of vilazodone significantly decreased firing in ventral tegmental area dopamine neurons; this effect persisted after 14-day treatment. The firing rate of norepinephrine neurons in the locus coeruleus was not significantly altered following 2-day treatment but did decrease following 14-day treatment. In the hippocampus, 14-day treatment with vilazodone significantly enhanced tonic activation, while having no effect on 5-HT reuptake. Vilazodone produced effects similar to conventional SSRIs while also inducing alterations in monoaminergic neurons that may be associated with its 5-HT1A properties and may have a role in the field of treatment resistant depression.
Débouchage canalisation en urgence 24h/7
Creators: name: Mendes
Publisher: name: Zenodo
Year: 2020
Subjects: Debouchage canalistaion 35

description: Distinguée dans son domaine par le professionnalisme des ses plombiers et sa qualité de service irréprochable, notre entreprise ETS Debouchage est considérée comme l’une des meilleures entreprises dans le domaine de débouchage des canalisations. Pour savoir plus vous pouvez consulter débouchage canalisation Ille-Et-Vilaine.
Horizon Europe: Open Science is the 'new' normal
Creators: name: Lazzeri, Emma
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: Open Science
Open Access
Reproducibility
European Commission
Horizon Europe

description: doi:10.5281/ZENODO.4817461
description: Starting from 2021, with the kickoff of the European Commission framework programme Horizon Europe, Open Science is expected to be the modus operandi in science. This presentation, given at the  Åpen forskning: Delta i European Open Science Cloud organised on may 26, 2021 form the Research Council of Norway, is presenting the Open Science strategy of the European Commission.
Living and Breathing Zendesk Tickets: Spam on Open Science Platforms
Creators: name: Cohoon, Johanna
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: open science
scholarly communications
infrastructure
spam

description: doi:10.5281/ZENODO.5765303
description: Lightning talk presented at FORCE2021 with early results from Johanna Cohoon's dissertation study, Negotiating Open Science [now complete, available at https://osf.io/vq8pj/]. Insights presented in the lightning talk were derived through interviews and observation conducted to understand the development, use, and non-use of the Open Science Framework. Participants referenced in this lightning talk are all employed to develop or improve the Open Science Framework. The 'Living and Breathing Zendesk Tickets: Spam on Open Science Platforms' lightning talk argues 1) existing open science platforms are the installed base that will likely be used to share research with the public and 2) spam is an issue on open science platforms that affects scientific budgets, inclusivity, and legitimacy. Because the research community is presently concerned with building public trust  in science, it is important to establish transparent practices for content moderation on open platforms. Rather than leaving this work only to platform developers, the FORCE11 community should be involved in determining best practices for moderating contributions to open science platforms.
Nachhaltigkeitspolitik als Schlüssel zu Stabilität, Sicherheit und Resilienz
Creators: name: Ginzky, Harald
name: Menger, Matthias
Publisher: name: Umweltbundesamt
Year: 2022
Subjects: subject: Nachhaltigkeitspolitik
subject: Nachhaltigkeit
subject: Politik
subject: Resilienz
subject: Sicherheit
subject: Ukraine
subject: Ukraine-Krise
subject: Stabilität
subject: Nachhaltigkeit | Strategien | Internationales

description: Der nachfolgende Text will über die Lösung der konkreten Ukraine-Krise hinausdenken und die Notwendigkeiten einer künftigenNachhaltigkeits-und Klimaschutzpolitik thematisieren. Zunächst wird eine Bestandsaufnahme in Bezug auf den Zusammenhang der Ukraine-Krise und der globalen und nationalen Nachhaltigkeitspolitiken unternommen. In einem zweiten Schritt werden basierend auf dieser Analyse einige Politikempfehlungen unterbreitet, die eine ambitionierte Nachhaltigkeitspolitik als Schlüssel für mehr Sicherheit, Stabilität und Resilienz aller Gesellschaften fordert.Hierbeiwird besonders auf die Verantwortung der industrialisierten Staaten und insbesondere von Deutschland und der EUeingegangen. Quelle: Bericht
description: The following text aims to think beyond the solution of the concrete Ukraine crisis and to address the necessities of a future sustainability and climate protection policy. First, a stocktaking is undertaken with regard to the connection between the Ukraine crisis and global and national sustainability policies. In a second step, based on this analysis, some policy recommendations are made, calling for an ambitious sustainability policy as the key for more security, stability and resilience of all societies. In this context, the responsibility of the industrialized states and in particular of Germany and the EU will be addressed in particular. Quelle: Bericht
description: Der Diskussionsbeitrag will über die Lösung der konkreten Ukraine-Krise hinausdenken und die Notwendigkeiten einer künftigen Nachhaltigkeits- und Klimaschutzpolitik thematisieren. Zunächst wird eine Bestandsaufnahme in Bezug auf den Zusammenhang der Ukraine-Krise und der globalen und nationalen Nachhaltigkeitspolitiken unternommen. In einem zweiten Schritt werden basierend auf dieser Analyse einige Politikempfehlungen unterbreitet, die eine ambitionierte Nachhaltigkeitspolitik als Schlüssel für mehr Sicherheit, Stabilität und ⁠Resilienz⁠ aller Gesellschaften fordert. Hierbei wird besonders auf die Verantwortung der industrialisierten Staaten und insbesondere von Deutschland und der EU eingegangen
An Empirical Investigation of Factors Affecting Perceived Quality and Well-Being of Children Using an Online Child Helpline
Creators: name: Van Dolen, Willemijn
name: Weinberg, Charles B.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Child helplines provide free, accessible, and confidential support for children suffering from issues such as violence and abuse. Helplines lack the barriers often associated with the use of many other health services; and for many children, the helpline is the first point of contact with any kind of child protection and an important venue to go to in times of socio-economic distress. For instance, more children attempt to call the helpline in times of high unemployment, and relatively more of those conversations are about violence. Empirical evidence is scarce regarding how to implement online chat communication to improve quality and the child’s well-being. In this study, we focus on the impact of chat duration, number of words, and the type of support. The results show that for children seeking emotional support, a longer chat negatively influences the immediate well-being and the counsellor needs to listen (i.e., not type), as relatively more child words result in higher evaluations. We conclude that for emotional support, the counsellor should be prepared to listen carefully, but also manage the duration. However, for children chatting for instrumental support, the counsellor needs to type more to create positive perceptions of quality. Since the impact of chat share is different for children seeking emotional support (negative) versus instrumental support (positive), counsellors need to be sensitive to early indicators of the reason for the chat.
Taming Translation Technology for L2 Writing: Documenting the Use of Free Online Translation Tools by ESL Students in a Writing Course
Creators: name: Farzi, Reza
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Free Online Translation Tools
ESL Writing
Machine Translation
Translation Technology

description: The present study explored the use of translation technology in second language (L2) writing by English as a Second Language (ESL) students at the University level. The appropriate role of translation, and specifically translation technology, in L2 curricula has been the subject of theoretical and practical debate. In order to address knowledge gaps relevant to this debate, the present study sought to document students’ current use of translation technology, specifically free online translation (FOT) tools, and their opinions about these tools. The study’s mixed-methods design included video observations and questionnaires regarding FOT use completed by 19 university students enrolled in a high intermediate-level ESL course. Semi-structured follow-up interviews were conducted with the six participants who were observed using FOT tools extensively on the video recordings. Results showed that high intermediate-level ESL students have a primarily positive attitude toward FOT tools. In addition, the majority of students reported using such tools regularly, even though only about one third of the students were actually observed using the tools significantly in the video recordings. Results are discussed in the context of the ongoing debate over whether and how translation technology should be used in L2 classrooms.
How the play element has changed in Australian football and the consequences of this change on the community
Creators: name: Duncan, Sam
Publisher: name: Swinburne
Year: 2024

description: This thesis is a theoretical analysis of the importance of the play element in developing communities and culture, using the Australian Football League (AFL) as a case study. Using the historical observations of Johan Huizinga and combining them with Pierre Bourdieu's concepts of fields and capital, a theoretical framework was created to illuminate the important role of play in creating communities. By developing this theory and applying it to the AFL, the analysis highlighted how the media and economic fields have transformed 'play' into 'display', which has changed the way AFL supporters relate to the game and subsequently weakened the AFL community.
Under-representation of the WHO African region in clinical trials of interventions against hepatitis B virus infection.
Creators: name: Delphin, Marion
name: Mohammed, Khadija Said
name: Downs, Louise O
name: Lumley, Sheila F
name: Waddilove, Elizabeth
name: Okanda, Dorcas
name: Aliyan, Nadia
name: Van Schalkwyk, Marije
name: Anderson, Motswedi
name: Ocama, Ponsiano
name: Maponga, Tongai
name: Torimiro, Judith
name: Iwuji, Collins
name: Ndung'u, Thumbi
name: Matthews, Philippa C
name: Taljaard, Jantjie
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Infectious Disease
subject: Infectious Disease
classificationCode: Immunology
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: Genetics & Genomics
subject: Genetics & Genomics

description: The WHO African region bears a disproportionate burden of morbidity and mortality related to chronic hepatitis B virus (HBV) infection and accounts for an estimated 70% of new HBV infections worldwide. We investigated the extent to which HBV clinical trials represented populations in this region by searching the WHO International Clinical Trials Registry Platform and ClinicalTrials.gov for interventional clinical trials published in English between database inception and May 29, 2023, using the search term "Hepatitis B". We identified 1804 unique clinical trials, of which 18 (1·0%) recorded involvement of the WHO African region. There is no evidence that the number of HBV clinical trials in this region has improved over time. The diversity of new interventions and industry sponsorship in the WHO African region were low, with trials of HBV comparing poorly with those of other endemic infectious diseases (eg, malaria, HIV, and SARS-CoV-2). HBV research and clinical trial investigations have neglected the WHO African region, leading to profound health inequities. HBV clinical trials are urgently needed to evaluate the efficacy of newly discovered therapeutics and to ensure that interventions can be equitably distributed and deployed as they become available.
Anatomy of Influence: The Decisive Effect of Northrop Frye’s Anatomy of Criticism on James Reaney’s Donnellys Trilogy, as Directed by Keith Turnbull
Creators: name: Loretto, Teri R.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012

description: Best known for his Donnellys Trilogy, Canadian playwright James Reaney completed his PHD under Northrop Frye. Frye’s thought and worldview are at the centre of these plays and although Reaney based his writing on a local legend from his childhood, it is undeniably grounded in Frye’s work, Anatomy of Criticism. Frye’s influence on Reaney becomes clear when Reaney’s trilogy is examined through the lens of Frye’s Anatomy. The plays manifest Frye’s structures concretely in space and time using props, setting, music, the spoken word and movement. An examination of the rehearsal hall methods of director Keith Turnbull reveals that Frye’s influence also extended to the actors’ preparation and the collective creation process that was critical to the resulting performances. Reviews and critiques, interviews with participants and an analysis of the trilogy in the context of Anatomy of Criticism give a greater understanding of the mechanics of the work and the resulting performances. In this study, elements of the plays are presented and discussed within the context of or with reference to Frye’s literary theory, making clear how the understanding of one contributes to the comprehension of the other. The relationship between a literary theory and live performance is here a powerful tool to understanding these theatrical works. This research establishes that it was also significant for the creation of one of Canada’s most pivotal dramatic works.
Introducing Open Science (OILS conference)
Creators: name: Röthlisberger, Melanie
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: Open Science
Open Access
Open Data

description: doi:10.5281/ZENODO.5525769
description: This presentation was given as an introduction to Open Science on the second day of the OILS conference 2021 (https://oils21.b2match.io/).
Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses
Creators: name: Sehring, Ivonne Margarete
name: Falah Mohammadi, Hossein
name: Haffner-Luntzer, Melanie
name: Ignatius, Anita
name: Huber-Lang, Markus
name: Weidinger, Gilbert
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Zebrafish
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Logperch
subject: Zebrabärbling

description: Successful regeneration requires the coordinated execution of multiple cellular responses to injury. In amputated zebrafish fins, mature osteoblasts dedifferentiate, migrate towards the injury, and form proliferative osteogenic blastema cells. We show that osteoblast migration is preceded by cell elongation and alignment along the proximodistal axis, which require actomyosin, but not microtubule (MT) turnover. Surprisingly, osteoblast dedifferentiation and migration can be uncoupled. Using pharmacological and genetic interventions, we found that NF-ĸB and retinoic acid signalling regulate dedifferentiation without affecting migration, while the complement system and actomyosin dynamics affect migration but not dedifferentiation. Furthermore, by removing bone at two locations within a fin ray, we established an injury model containing two injury sites. We found that osteoblasts dedifferentiate at and migrate towards both sites, while accumulation of osteogenic progenitor cells and regenerative bone formation only occur at the distal-facing injury. Together, these data indicate that osteoblast dedifferentiation and migration represent generic injury responses that are differentially regulated and can occur independently of each other and of regenerative growth. We conclude that successful fin bone regeneration appears to involve the coordinated execution of generic and regeneration-specific responses of osteoblasts to injury.
Open Science in a nutshell
Creators: name: Giglia, Elena
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: Horizon Europe, Open Science

description: doi:10.5281/ZENODO.5535778
description: Introduction to Open Science: why and how, the European framework (EOSC and FAIR data), Open Science practices in Horizon2020 and Horizon Europe. Presented on Sept.29, 2021 at the SAPIENS ( Sustainability and Procurement in International, European, and National Systems) network, Turin.
Extended state observer based repetitive control and applications
Creators: name: Sayem, A. H. M.
Publisher: name: Swinburne
Year: 2024

description: Many examples in nature show periodic characteristics ranging from the orbital motion of the universe to the rhythm of the heart. There are various instances where the mathematical model of the plant is not available and most of the controller design is dependent on the plant parameters. The novel algorithm proposed in this thesis, will be able to design the controller without the plant model. Moreover, it will eliminate any type of input and output disturbances from the system. As a result, the system will be efficient and disturbance free.
Austrian Transition To Open Science
Creators: name: Danowski, Patrick
Publisher: name: Forschungzentrum Jülich
Year: 2016
Subjects: Open Access
PASTEUR4OA
Presentation

description: doi:10.5281/zenodo.54721
description: Presentation given at the PASTEUR4OA conference - Green Light for Open Access: Aligning Europe’s OA Policies, Amsterdam, 17th-18th May 2016.