Additional file 1 of Green synthesis of glyco-CuInS2 QDs with visible/NIR dual emission for 3D multicellular tumor spheroid and in vivo imaging
Creators: name: Guan, Xiaolin
name: Zhang, Liyuan
name: Lai, Shoujun
name: Zhang, Jiaming
name: Wei, Jingyu
name: Wang, Kang
name: Zhang, Wentao
name: Li, Chenghao
name: Tong, Jinhui
name: Lei, Ziqiang
Publisher: name: figshare
Year: 2023
Subjects: Biophysics
Biochemistry
Space Science
Physical Sciences not elsewhere classified
Medicine
Cell Biology
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Additional file 1: Figure S1 1H NMR hydrogen spectra of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs and (d) Glu-CuInS2 QDs (room temperature, D2O). Figure S2. MS spectra of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs and (d) Glu-CuInS2 QDs. Figure S3. Fluorescence emission spectra of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs, and (d) Glu-CuInS2 QDs synthesized at different dose ratios. (Inset: relationship between dose ratio and luminescence intensity of CuInS2 QDs). Figure S4. Fluorescence emission spectra of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs, and (d) Glu-CuInS2 QDs synthesized under different pH conditions. (Inset: relationship between pH and luminescence intensity of CuInS2 QDs). Figure S5. Fluorescence emission spectra of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs, and (d) Glu-CuInS2 QDs synthesized under different temperature conditions. (Inset: Relationship between temperature and luminescence intensity of CuInS2 QDs). Figure S6. The SEM–EDS analysis of Fru-CuInS2, Gal-CuInS2, Man-CuInS2 and Glu-CuInS2 QDs. Figure S7. The EDX elemental mapping of Fru-CuInS2, Gal-CuInS2, Man-CuInS2 and Glu-CuInS2 QDs. Figure S8. The XPS survey spectra of (a)Fru-CuInS2 QDs, (b)Gal-CuInS2 QDs, (c)Man-CuInS2 QDs, and (d)Glu-CuInS2 QDs. Figure S9. Zeta potential values of glyco-CuInS2 QDs. Figure S10. TEM images of Fru-CuInS2, Gal-CuInS2, Man-CuInS2 and Glu-CuInS2 QDs at a scale of 5 nm after fourteen days. Figure S11. DOS and PDOS of Fructose molecules adsorbed on CuInS2(001) before and after (a) DOS of CuInS2(001) system, (b) Fructose molecules adsorbed on DOS of CuInS2(001) system, (c) PDOS of CuInS2(001) system, (d) Fructose molecules adsorbed on DOS of CuInS2(001) system. Figure S12. The UV–Vis absorption spectra of Fru-CuInS2, Gal-CuInS2, Man-CuInS2 and Glu-CuInS2 QDs, respectively. Figure S13. Fluorescence lifetimes of glyco-CuInS2 QDs. Figure S14. Excitation and emission fluorescence spectra of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs, and (d) Glu-CuInS2 QDs. Figure S15. Fluorescence stabilities of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs and (d) Glu-CuInS2 QDs in solution. The black, red and blue lines refer to the fluorescence spectra of glyco-CuInS2 QDs after 0, 7, and 14 days, respectively. Figure S16. Fluorescence spectra of the pH response of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs, and (d) Glu-CuInS2 QDs. (Inset: relationship between pH and luminescence intensity of CuInS2 QDs). Figure S17. MTT assay to detect changes in cellular activity of cancer cells after the addition of 20,40,60,80,100 μg/mL of (a) Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs, and (d) Glu-CuInS2 QDs, respectively. Figure S18. Fluorescence intensities of (a)Fru-CuInS2 QDs, (b) Gal-CuInS2 QDs, (c) Man-CuInS2 QDs, and(d) Glu-CuInS2 QDs imaged under fluorescence microscopy after incubation of zebrafish for 1 h, respectively. Table S1. Exploration of optimal synthesis conditions for glyco-CuInS2 QDs. Table S2. The photophysical properties of glyco-CuInS2 QDs.