cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Strongest coronal magnetic fields in solar cycles 23-24: probing, statistics, and implications
Creators: name: Fedenev, V. V.
name: Anfinogentov, S. A.
name: Fleishman, G. D.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Strong coronal magnetic field, when present, manifests itself as bright microwave sources at high frequencies produced by gyroresonant (GR) emission mechanism in thermal coronal plasma. The highest frequency at which this emission is observed is proportional to the absolute value of the strongest coronal magnetic field on the line of sight. Although no coronal magnetic field larger than roughly 2,000 G was expected, recently the field at least twice larger has been reported. Here, we report a search for and statistical study of such strong coronal magnetic fields using high-frequency GR emission. A historic record of spatially resolved microwave observations at high frequencies, 17 and 34 GHz, is available from Nobeyama RadioHeliograph for more than 20 years (1995-2018). Here we employ this data set to identify sources of bright GR emission at 34 GHz and perform a statistical analysis of the identified GR cases to quantify the strongest coronal magnetic fields during two solar cycles. We found that although active regions with the strong magnetic field are relatively rare (less than 1% of all active regions), they appear regularly on the Sun. These active regions are associated with prominent manifestations of solar activity.
Landau energy spectrum and quantum oscillator model for twisted N-enlarged Newton-Hooke space-time
Creators: name: Daszkiewicz, Marcin
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We derive the energy levels for oscillator model defined on the twisted N-enlarged Newton-Hooke space-time, i.e., we find time-dependent eigenvalues and corresponding time-dependent eigenstates. We also demonstrate that for a particular choice of deformation parameters of phase space the above spectrum can be identified with the time-dependent Landau one.
description: 10 pages, Latex source. arXiv admin note: substantial text overlap with arXiv:1302.0827
Protocol preregistration for Social Media in Undergraduate Teaching and Learning: A Scoping Review Protocol
Creators: name: Hayman, Richard
name: Smith, Erika E.
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Communication
subject: Educational Methods
subject: Education
subject: Social Media
subject: Scholarship of Teaching and Learning
subject: Higher Education
subject: Social and Behavioral Sciences
subject: Communication Technology and New Media
subject: Educational Assessment, Evaluation, and Research

description: This is a protocol preregistration for a scoping review study examining the use of social media in undergraduate teaching and learning.
Neutron Interferometry constrains dark energy chameleon fields
Creators: name: Lemmel, H.
name: Brax, Ph.
name: Ivanov, A. N.
name: Jenke, T.
name: Pignol, G.
name: Pitschmann, M.
name: Potocar, T.
name: Wellenzohn, M.
name: Zawisky, M.
name: Abele, H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present phase shift measurements for neutron matter waves in vacuum and in low pressure Helium using a method originally developed for neutron scattering length measurements in neutron interferometry. We search for phase shifts associated with a coupling to scalar fields. We set stringent limits for a scalar chameleon field, a prominent quintessence dark energy candidate. We find that the coupling constant $β$ is less than 1.9 $\times10^7$~for $n=1$ at 95\% confidence level, where $n$ is an input parameter of the self--interaction of the chameleon field $φ$ inversely proportional to $φ^n$.
description: 7 pages, 4 figures
New Challenges for Content Privacy in Speech and Audio
Creators: name: Williams, Jennifer
name: Pizzi, Karla
name: Das, Shuvayanti
name: Noe, Paul-Gauthier
Publisher: name: arXiv
Year: 2023
Subjects: subject: Audio and Speech Processing (eess.AS)
subject: Cryptography and Security (cs.CR)
subject: Sound (cs.SD)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Privacy in speech and audio has many facets. A particularly under-developed area of privacy in this domain involves consideration for information related to content and context. Speech content can include words and their meaning or even stylistic markers, pathological speech, intonation patterns, or emotion. More generally, audio captured in-the-wild may contain background speech or reveal contextual information such as markers of location, room characteristics, paralinguistic sounds, or other audible events. Audio recording devices and speech technologies are becoming increasingly commonplace in everyday life. At the same time, commercialised speech and audio technologies do not provide consumers with a range of privacy choices. Even where privacy is regulated or protected by law, technical solutions to privacy assurance and enforcement fall short. This position paper introduces three important and timely research challenges for content privacy in speech and audio. We highlight current gaps and opportunities, and identify focus areas, that could have significant implications for developing ethical and safer speech technologies.
description: Accepted for publication in ISCA SPSC Symposium 2022
Stress and Failure Analysis of Rapidly Rotating Asteroid (29075) 1950 DA
Creators: name: Hirabayashi, Masatoshi
name: Scheeres, Daniel J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Rozitis et al. recently reported that near-Earth asteroid (29075) 1950 DA, whose bulk density ranges from 1.0 g/cm3 to 2.4 g/cm3, is a rubble pile and requires a cohesive strength of at least 44 Pa to 74 Pa to keep from failing due to its fast spin period. Since their technique for giving failure conditions required the averaged stress over the whole volume, it discarded information about the asteroid's failure mode and internal stress condition. This paper develops a finite element model and revisits the stress and failure analysis of 1950 DA. For the modeling, we do not consider material-hardening and softening. Under the assumption of an associated flow rule and uniform material distribution, we identify the deformation process of 1950 DA when its constant cohesion reaches the lowest value that keeps its current shape. The results show that to avoid structural failure the internal core requires a cohesive strength of at least 75 Pa - 85 Pa. It suggests that for the failure mode of this body, the internal core first fails structurally, followed by the surface region. This implies that if cohesion is constant over the whole volume, the equatorial ridge of 1950 DA results from a material flow going outward along the equatorial plane in the internal core, but not from a landslide as has been hypothesized. This has additional implications for the likely density of the interior of the body.
description: Accepted for publication in The Astrophysical Journal Letters. 16 pages and 4 figures. MH appreciates Eleanor Matheson, Keith A. Holsapple, Carlos A. Felippa, Ben Rozitis, and Paul S\'anchez for their discussions
Fatty acid profile driven by maternal diet is associated with the composition of human milk microbiota
Creators: name: Aljumaah, Mashael R.
name: Marsh, Alan J.
name: Neville, Jessica
name: Azcarate-Peril, M. Andrea
name: Wheeler, Michael D.
name: Dean, Lisa L.
name: Perrin, Maryanne T.
name: Pawlak, Roman
name: Hines, Ian N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Little is known regarding the impact of diet on the breast milk microbiome. We hypothesized that vegan, vegetarian, and omnivore diets would impact the human milk microbiota. We also aimed to explore associations between human milk fatty acid concentrations and microbial composition. A cross-sectional microbiome diversity analysis of human milk samples (N = 72) was performed using 16S rRNA amplicon sequencing. Human milk microbial diversity was not associated with diet type. However, analysis of microbiome in relation to fatty acid profiles revealed significant differences in the overall composition of the human milk microbiota between high (> 0.7% of total fat) and low (< 0.7%) trans-fatty acid groups (TF) (p = 0.039, pairwise PERMANOVA p = 0.035), high (> 40%) versus low (< 40%) saturated fatty acids (UniFrac p = 0.083, PERMANOVA p = 0.094), and high (>60%) versus low (<60%) unsaturated fatty acids (UF) (UniFrac p = 0.094, PERMANOVA p = 0.093). 84% of samples from omnivore mothers were in the high TF group compared to only 12% of samples from vegans. Gut-associated species (Faecalibacterium, Blautia, Roseburia and Subdoligranulum) and Lactobacillus were characteristic of both high UF and TF groups, but not the low-fat groups. Functional analysis revealed 2,4-dichlorophenol 6-monooxygenase was differentially abundant in the high UF group. Although microbiome diversity did not differ by diet type, TF breast milk content differed by diet group, highlighting the relationship between maternal diet and the microbial profile of human milk.
Third order Lovelock black branes in the presence of a nonlinear electromagnetic field
Creators: name: Hendi, S. H.
name: Panahiyan, S.
name: Mohammadpour, H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider third order Lovelock gravity coupled to an U(1) gauge field for which its Lagrangian is given by a power of Maxwell invariant. In this paper, we present a class of horizon flat rotating black branes and investigate their geometrical properties and the effect of nonlinearity on the solutions. We use some known formulas and methods to calculate thermodynamic and conserved quantities. Finally, we check the satisfaction of the first law of thermodynamics.
description: 6 pages, 3 figures
Additional file 1 of Long-term longitudinal study on swine VML model
Creators: name: De Paolis, Francesca
name: Testa, Stefano
name: Guarnaccia, Gabriele
name: Reggio, Alessio
name: Fornetti, Ersilia
name: Cicciarelli, Felice
name: Deodati, Rebecca
name: Bernardini, Sergio
name: Peluso, Daniele
name: Baldi, Jacopo
name: Biagini, Roberto
name: Bellisari, Flavia Cobianchi
name: Izzo, Antonio
name: Sgalambro, Ferruccio
name: Arrigoni, Francesco
name: Rizzo, Francesco
name: Cannata, Stefano
name: Sciarra, Tommaso
name: Fuoco, Claudia
name: Gargioli, Cesare
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Supplementary Materials: Supp. Figure 1. Evaluation of macrophage infiltrate using ImageJ software. Supp. Figure 2. Calculation of the Mean Gray Value starting from ultrasound scans using ImageJ software.
คำกล่าวนำ
Creators: name: Sano-Franchini, Jennifer
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2022
Subjects: -

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 22, 1, -
Spin 1 condensates at thermal equilibrium : a $SU(3)$ coherent state approach
Creators: name: Corre, V.
name: Zibold, T.
name: Frapolli, C.
name: Shao, L.
name: Dalibard, J.
name: Gerbier, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We propose a theoretical framework based on $SU(3)$ coherent states as a convenient tool to describe the collective state of a Bose-Einstein condensate of spin 1 atoms at thermal equilibrium. We work within the single-mode approximation, which assumes that all atoms condense in the same spatial mode. In this system, the magnetization $m_z$ is conserved to a very good approximation. This conservation law is included by introducing a prior distribution for $m_z$ and constructing a generalized statistical ensemble that preserves its first moments. In the limit of large particle numbers, we construct the partition function at thermal equilibrium and use it to compute various quantities of experimental interest, such as the probability distribution function and moments of the population in each Zeeman state. When $N$ is large but finite (as in typical experiments, where $N\sim 10^3-10^5$), we find that fluctuations of the collective spin can be important.
THE ROLE OF IMMUNOTHERAPY IN UNEXPLAINED RECURRENT ABORTION.  A CASE REPORT AND REVIEW OF LITERATURE
Creators: name: Ruchi Srivastava
name: Sanjeevini Kaul
name: Mayuri Ahuja
name: Sagupta Taranum
Publisher: name: Zenodo
Year: 2023
Subjects: Recurrent Abortion, Ivimmunoglobulin, Successful Outcome, OGTT: Oral Glucose Tolerance Test.

description: Abstract 
Recurrent abortion refers to failure of pregnancy of three or more pregnancies with the same partner with the incidence of 1 % of the pregnancies. Many modalities of treatment are available for the management but the role of immunotherapy needs more exploration. Due to high cost and less knowledge of such therapy such modality of treatment is still under exploration.  No guidelines have been set for their use in the management of recurrent abortion. With the case report we will bring about a successful outcome of G5 A4 of recurrent abortion managed with immunotherapy at our institute. This article will also include reviewof literature regarding the type, dosage and the effectiveness of immunotherapy in the management of recurrent abortion.
Tuning electronic properties and contact type in van der Waals heterostructures of bilayer SnS and graphene
Creators: name: Ebrahimi, M. R.
name: Vazifehshenas, T.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Using first-principles calculations, we study the structural and electronic properties of the bilayer SnS/graphene, bilayer SnS/bilayer graphene (AA-stacked), bilayer SnS/bilayer graphene (AB-stacked) and monolayer SnS/graphene/monolayer SnS van der Waals (vdW) heterostructures. Electronic properties of all components of the vdW heterostructures are well preserved, which reflects the weakness of the vdW interaction. In the cases of bilayer SnS/graphene and bilayer SnS/bilayer graphene (AA-stacked), an Ohmic contact is formed which can be turned first into p-type and then into n-type Schottky contacts via application of an external electric field. Calculations show that an Ohmic contact is also formed at the interface of bilayer SnS/bilayer graphene (AB-stacked) heterostructure, but interestingly, by applying the perpendicular electric field a transition from semimetal/semiconductor contact to semiconductor/semiconductor one occurs which can enhance its optical properties. Alternatively, in the monolayer SnS/graphene/monolayer SnS vdW heterosructure, a p-type Schottky contact is established that changes into Ohmic contact under an applied electric field. Our results clearly indicate that the electronic properties of the vdW heterostructures can be tuned efficiently by external electric field, which is important in designing of new nanoelectronic devices.
description: 12 pages, 11 figures
Additional file 1 of Phosphorylation: new star of pathogenesis and treatment in steatotic liver disease
Creators: name: Lv, Tiansu
name: Lou, Yan
name: Yan, Qianhua
name: Nie, Lijuan
name: Cheng, Zhe
name: Zhou, Xiqiao
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. 17718536_TiansuLv.docx
Platelet in thrombo-inflammation: Unraveling new therapeutic targets
Creators: name: Tyagi, Tarun
name: Antoniak, Silvio
name: Sharma, Swati
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: In the broad range of human diseases, thrombo-inflammation appears as a clinical manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that is recognized as thrombosis and inflammation of superficial veins. However, it is more hazardous when developed in the microvasculature of injured/inflamed/infected tissues and organs. Several diseases like sepsis and ischemia-reperfusion can cause formation of microvascular thrombosis subsequently leading to thrombo-inflammation. Thrombo-inflammation can also occur in cases of antiphospholipid syndrome, preeclampsia, sickle cell disease, bacterial and viral infection. One of the major contributors to thrombo-inflammation is the loss of normal anti-thrombotic and anti-inflammatory potential of the endothelial cells of vasculature. This manifest itself in the form of dysregulation of the coagulation pathway and complement system, pathologic platelet activation, and increased recruitment of leukocyte within the microvasculature. The role of platelets in hemostasis and formation of thrombi under pathologic and non-pathologic conditions is well established. Platelets are anucleate cells known for their essential role in primary hemostasis and the coagulation pathway. In recent years, studies provide strong evidence for the critical involvement of platelets in inflammatory processes like acute ischemic stroke, and viral infections like Coronavirus disease 2019 (COVID-19). This has encouraged the researchers to investigate the contribution of platelets in the pathology of various thrombo-inflammatory diseases. The inhibition of platelet surface receptors or their intracellular signaling which mediate initial platelet activation and adhesion might prove to be suitable targets in thrombo-inflammatory disorders. Thus, the present review summarizes the concept and mechanism of platelet signaling and briefly discuss their role in sterile and non-sterile thrombo-inflammation, with the emphasis on role of platelets in COVID-19 induced thrombo-inflammation. The aim of this review is to summarize the recent developments in deciphering the role of the platelets in thrombo-inflammation and discuss their potential as pharmaceutical targets.
Molecular hydrogen and its proxies HCO$^+$ and CO in the diffuse interstellar medium
Creators: name: Liszt, Harvey
name: Gerin, Maryvonne
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: There is a robust polyatomic chemistry in diffuse, partially-molecular interstellar gas that is readily accessible in absorption at radio/mm/sub-mm wavelengths. Accurate column densities are derived owing to the weak internal excitation, so relative molecular abundances are well known with respect to each other but not with respect to H2. Here we consider the use of proxies for hydrogen column densities N(H2) and N(H) = N(HI)+2N(H2) based on measurements of HCO+ absorption and CO emission and absorption, and we compare these with results obtained by others when observing HI, H2 and CO toward stars and AGN. We consider the use of HCO+ as a proxy for H2 and show that the assumption of a relative abundance N(H2) = N(HCO+)/3x10^{-9} gives the same view of the atomic-molecular hydrogen transition that is seen in UV absorption toward stars. CO on the other hand shows differences between the radio and optical regimes because emission is always detected when N(\hcop) > 6x10^{11}\pcc or N(H2) > 2x10^20\pcc. Wide variations in the integrated CO {J=1-0} brightness W_CO and N(CO)/N(H2) imply equivalent variations in the CO-H2 conversion factor even while the ensemble mean is near the usual Galactic values. Gas/reddening ratios found in absorption toward stars, N(H)/E(B-V) = 6.2x10^21 H \pcc/mag overall or 6.8x10^21 H \pcc/mag for sightlines at E(B-V) <= 0.08 mag lacking H2 are well below the Galactic mean measured at low reddening and high Galactic latitude, 8.3x10^21 H \pcc/mag.
description: Accepted for The Astrophysical Journal
Heating or Cooling: Study of Advective Heat Transport in the Inflow and the Outflow of Optically Thin Advection-dominated Accretion Flows
Creators: name: Jiao, Cheng-Liang
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Advection is believed to be the dominant cooling mechanism in optically thin advection-dominated accretion flows (ADAF's). When outflow is considered, however, the first impression is that advection should be of opposite sign in the inflow and the outflow, due to the opposite direction of radial motion. Then how is the energy balance achieved simultaneously? We investigate the problem in this paper, analysing the profiles of different components of advection with self-similar solutions of ADAF's in spherical coordinates ($rθϕ$). We find that for $n < 3γ/2-1$, where $n$ is the density index in $ρ\propto r^{-n}$ and $γ$ is the heat capacity ratio, the radial advection is a heating mechanism in the inflow and a cooling mechanism in the outflow. It becomes 0 for $n = 3γ/2-1$, and turns to a cooling mechanism in the inflow and a heating mechanism in the outflow for $n > 3γ/2-1$. The energy conservation is only achieved when the latitudinal ($θ$-direction) advection is considered, which takes an appropriate value to maintain energy balance, so that the overall effect of advection, no matter the parameter choices, is always a cooling mechanism that cancels out the viscous heating everywhere. For the extreme case of $n=3/2$, latitudinal motion stops, viscous heating is balanced solely by radial advection, and no outflow is developed.
description: 9 pages, 4 figures, accepted by ApJ
Development and Validation of a New Self-report Measure of Maladptive Overcontrol: Internal Psychometric Analysis
Creators: name: Winder, Belinda
name: Lambert, Alex
name: Pires, Pedro
name: Norman, Christine
name: Hamilton, Laura
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Clinical Psychology
subject: Personality and Social Contexts
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: This study is being conducted as part of a wider of developing and validating a new self-report measure of maladaptive overcontrol. The aim of the study is internal psychometric analysis of the scale.
Localized light chain amyloidosis: A self-limited plasmacytic B-cell lymphoproliferative disorder
Creators: name: Lichtman, Eben I.
name: Martínez, José C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Immunoglobulin light chain amyloidosis can be either systemic or localized. Although these conditions share a similar name, they are strikingly different. Localized light chain amyloidosis has been challenging to characterize due to its lower incidence and highly heterogeneous clinical presentation. Here, we review the emerging literature, emphasizing recent reports on large cohorts of patients with localized amyloidosis, and provide insights into this condition’s pathology and natural history. We find that patients with localized amyloidosis have an excellent prognosis with overall survival similar to that of the general population. Furthermore, the risk of progression to systemic disease is low and likely represents initial mischaracterization as localized disease. Therefore, we argue for the incorporation of more sensitive techniques to rule out systemic disease at diagnosis. Despite increasing mechanistic understanding of this condition, much remains to be discovered regarding the cellular clonal evolution and the molecular processes that give rise to localized amyloid formation. While localized surgical resection of symptomatic disease is typically the treatment of choice, the presentation of this disease across the spectrum of plasmacytic B-cell lymphoproliferative disorders, and the frequent lack of an identifiable neoplastic clone, can make therapy selection a challenge in the uncommon situation that systemic chemotherapy is required.
Feminism in Photography
Creators: name: Gamo, Francis
Publisher: name: Zenodo
Year: 2023
Subjects: Feminism in Photography

description: Abstract
 Feminism has challenged beliefs where there are prevailing inequalities
 between men and women. In Saudi Arabia, where women are considered secondclass
 citizens, photography is an explorable field when it comes to representation of
 both sexes. This study sought to determine the profile of the Filipino photographers
 professionally practicing photography in Riyadh along gender, age, highest
 educational attainment, and schools/institution where trainings are acquired;
 examine the gap between the percentage of female and male photographerrespondents
 based on gender; analyze the significance of gender in the enthusiasm
 of the respondents; identify the factors that affect the level of engagement in
 photography of the female and male photographers in Riyadh; and propose
 recommendations to enhance the integration of principles of feminism in
 photography. Findings show that 70. 83% of the respondents were female
 photographers. It was also found that 58.33 % of the respondents were 18-34 years
 old, 87.5% attained tertiary education and 33.3% acquired trainings in photography
 in COMSOFIL.
 Findings show that there is a huge gap of 41.67% between the female and
 male photographers. Respondents also agree on the perceived significance of
 gender in the practice of photography with a grand mean of 3.27. It only implies that
 the respondents recognize the roles and relevance of gender in their engagement in
 photography. A grand mean of 3.55 shows that the respondents agreed on the
 factors Feminism in Photography xiii
 that affect the level of engagement in photography. With the foregoing findings, it was
 concluded that the profile of the respondents is varied, more females are involved in
 photography, gender is significant in the practice of photography. The level of engagement
 in photography is affected by several factors and gender representation, fresh
 perspective in their approach to a specific theme, collaboration with peers and
 clients, familiarity of context, marketing and networking themselves to increase
 income, and learning new techniques are ways to enhance their level of
 engagement in photography.
Additional file 1 of The dynamic landscape of chromatin accessibility and active regulatory elements in the mediobasal hypothalamus influences the seasonal activation of the reproductive axis in the male quail under long light exposure
Creators: name: Chang, Jianye
name: Xu, Yanglong
name: Fu, Yuting
name: Liu, Jiaxin
name: Jiang, Danli
name: Pan, Jianqiu
name: Ouyang, Hongjia
name: Liu, Wenjun
name: Xu, Jin
name: Tian, Yunbo
name: Huang, Yunmao
name: Ruan, Jue
name: Shen, Xu
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1. Number of insert length statistics for each ATAC-seq library. Fig. S2. Pearson corrolation analysis for each ATAC-seq library. Fig. S3. The number of peaks called by MACS2 in each ATAC-seq library, the dotted line represents the numerical value of the reproducible peaks under this treatment. Fig. S4. Peak density in Japanese quail's genome. The outer circle is the chromosome, followed by the gene density distribution, and then the peak density distribution of SD28, LD3, LD7, and LD28. Some regions with high gene density and high peak distribution are selected by the lavender rectangle box. Fig. S5. Top 30 transcription factors enriched on the common peak at different time points. (A) SD28. (B) LD3. (C) LD7. (D) LD28. Fig S6. The volcano plot shows the difference analysis of ATAC-seq at SD28, LD3, LD7, and LD28 time points by DESEQ2 package. with blue dots representing the up-regulated region and red dots representing the down-regulated region. Fig. S7. The number and distribution statistics of chromatin regional differences in ATAC-seq at different time points. Fig. S8. GO enrichment analysis for K-means clustering of differential chromatin regions. Fig. S9. Binding characteristics of THRB transcription factors in DAP-seq. DAP-seq analysis of Japanese quail THRB protein. Fig. S10. Gene ontology analysis in biology process (BP) of the target site of THRB. Fig. S11. Gene ontology analysis in cellular component (CC) of the target site of THRB. Fig. S12. Gene ontology analysis in molecular function (MF) of the target site of THRB.
Hamiltonian analysis for Lifshitz type Fields
Creators: name: Gaona, Alejandro
name: Romero, Juan M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Using the Dirac Method, we study the Hamiltonian consistency for three field theories. First we study the electrodynamics a la Hořava and we show that this system is consistent for an arbitrary dynamical exponent $z.$ Second, we study a Lifshitz type electrodynamics, which was proposed in [1]. For this last system we found that the canonical momentum and the electrical field are related through a Proca type Green function, however this system is consistent. In addition, we show that the anisotropic Yang-Mills theory with dynamical exponent $z=2$ is consistent. Finally, we study a generalized anisotropic Yang-Mills theory and we show that this last system is consistent too.
description: Accepted for publication in Mod.Phys.Lett. A
Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis
Creators: name: Doyle, Alfred D.
name: Cruse, Glenn
name: Snider, Douglas B.
name: Chen, Celine
name: Brodsky, David
name: Dellon, Evan S.
name: Blikslager, Anthony
name: Odle, Jack
name: Cortes, Lizette M.
name: Käser, Tobias
name: Laster, Scott M.
name: Dawson, Harry D.
name: Wright, Benjamin L.
name: Pridgen, Tiffany
name: Masuda, Mia Y.
name: Putikova, Arina
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Eosinophilic esophagitis (EoE) is a chronic allergy-mediated condition with an increasing incidence in both children and adults. Despite EoE's strong impact on human health and welfare, there is a large unmet need for treatments with only one recently FDA-approved medication for EoE. The goal of this study was to establish swine as a relevant large animal model for translational biomedical research in EoE with the potential to facilitate development of therapeutics. We recently showed that after intraperitoneal sensitization and oral challenge with the food allergen hen egg white protein (HEWP), swine develop esophageal eosinophilia—a hallmark of human EoE. Herein, we used a similar sensitization and challenge treatment and evaluated immunological and pathological markers associated with human EoE. Our data demonstrate that the incorporated sensitization and challenge treatment induces (i) a systemic T-helper 2 and IgE response, (ii) a local expression of eotaxin-1 and other allergy-related immune markers, (iii) esophageal eosinophilia (>15 eosinophils/0.24 mm2), and (iv) esophageal endoscopic findings including linear furrows and white exudates. Thereby, we demonstrate that our sensitization and oral challenge protocol not only induces the underlying immune markers but also the micro- and macro-pathological hallmarks of human EoE. This swine model for EoE represents a novel relevant large animal model that can drive translational biomedical research to develop urgently needed treatment strategies for EoE.
Study of Dynamic Interaction Between Low Re Aerodynamic Load and Flexible-Biomimetic Wings with Tailorable Stiffness by FSI Modeling
Creators: name: Boughou, Smail
name: Boukharfane, Radouan
name: Inman, Daniel J.
name: Omar, Ashraf A.
name: Elsayed, Omer A.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In the present work, we investigate dynamic interaction and response of flexible bio-inspired morphing wing structure to a low Reynolds aerodynamic load. The aspects of inspiration are as follows. First, the segmentation of the wing into rigid and flexible segments. Considering a leading edge constitution of bone and muscle. In addition to a flexible trailing edge composed of feathers. Second, the material properties provided by experimental biology in literature are adopted such as the bending stiffness and Young's modulus. The development of numerical models allowing non uniform distribution of properties are developed and implemented into an OpenFoam finite volume solver that couples fluid dynamics to a structural solid dynamics solver through the FSI interface. In the course of this work, the validation is performed for a NACA6409 airfoil considering a rigid segment of 40\% and flexible segment 60\% chord length in order to test the aero-structure behavior for an aerodynamic load of air flow at low Reynolds number of $\boldsymbol{5\times 10^5}$ for the fluid and feather inspired material properties. The results suggest that bio-inspired techniques can be reproduced in engineering configurations.
description: This is the author's version of an article that has been published at 2023 AIAA SciTech Forum - 23-27 January 2023. The final version of record is available at: \url{https://arc.aiaa.org/doi/abs/10.2514/6.2023-0826}
Core functions of a financial navigation intervention: An in-depth assessment of the Lessening the Impact of Financial Toxicity (LIFT) intervention to inform adaptation and scale-up in diverse oncology care settings
Creators: name: Biddell, Caitlin B.
name: Rogers, Cindy
name: Birken, Sarah A.
name: Gellin, Mindy
name: Manning, Michelle L.
name: Wheeler, Stephanie B.
name: Rosenstein, Donald L.
name: Wagi, Cheyenne R.
name: Strom, Carla
name: Bell, Ronny Antonio
name: Rodriguez, Julia
name: Padilla, Neda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Background Lessening the Impact of Financial Toxicity (LIFT) is an intervention designed to address financial toxicity (FT) and improve cancer care access and outcomes through financial navigation (FN). FN identifies patients at risk for FT, assesses eligibility for financial support, and develops strategies to cope with those costs. LIFT successfully reduced FT and improved care access in a preliminary study among patients with high levels of FT in a single large academic cancer center. Adapting LIFT requires distinguishing between core functions (components that are key to its implementation and effectiveness) and forms (specific activities that carry out core functions). Our objective was to complete the first stage of adaptation, identifying LIFT core functions. Methods We reviewed LIFT's protocol and internal standard-operating procedures. We then conducted 45–90 min in-depth interviews, using Kirk's method of identifying core functions, with key LIFT staff (N = 8), including the principal investigators. Interviews focused on participant roles and intervention implementation. Recorded interviews were transcribed verbatim. Using ATLAS.ti and a codebook based on the Model for Adaptation Design and Impact, we coded interview transcripts. Through thematic analysis, we then identified themes related to LIFT's intervention and implementation core functions. Two report back sessions with interview participants were incorporated to further refine themes. Results Six intervention core functions (i.e., what makes LIFT effective) and five implementation core functions (i.e., what facilitated LIFT's implementation) were identified to be sufficient to reduce FT. Intervention core functions included systematically cataloging knowledge and tracking patient-specific information related to eligibility criteria for FT relief. Repeat contacts between the financial navigator and participant created an ongoing relationship, removing common barriers to accessing resources. Implementation core functions included having engaged sites with the resources and willingness necessary to implement FN. Developing navigators' capabilities to implement LIFT—through training, an established case management system, and connections to peer navigators—were also identified as implementation core functions. Conclusion This study adds to the growing evidence on FN by characterizing intervention and implementation core functions, a critical step toward promoting LIFT's implementation and effectiveness.
Development and Validation of the Health-Related Proactive Behavior at Work (HR-ProW) Scale
Creators: name: Kensei Ogawa
name: Landskron, Sarah Jasmin
name: Kühnel, Jana
name: Zils, Johanna
name: Mohammed, Amin
name: Ziegler, Jennifer
name: Schleupner, Ricarda
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Industrial and Organizational Psychology
subject: Health Psychology
subject: Quantitative Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: HR-ProW
subject: Health-Related Proactivity at Work
subject: Proactivity
subject: Scale Development

description: The aim of the project was to develop a valid and reliable instrument, namely the HR-ProW scale, for assessing health-related proactive behavior at work. The development of the HR-ProW scale is based on an extensive literature research and a review of existing scales assessing proactive behavior concepts. The structure of the HR-ProW scale is validated by an exploratory and a confirmatory factor analysis. Furthermore its relationship to theoretically related and unrelated constructs was assessed.
Polarisation of cells and soft objects driven by mechanical interactions: Consequences for migration and chemotaxis
Creators: name: Leoni, M.
name: Sens, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Biological Physics (physics.bio-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We study a generic model for the polarisation and motility of self-propelled soft objects, biological cells or biomimetic systems, interacting with a viscous substrate. The active forces generated by the cell on the substrate are modelled by means of oscillating force multipoles at the cell-substrate interface. Symmetry breaking and cell polarisation for a range of cell sizes naturally `emerge' from long range mechanical interactions between oscillating units, mediated both by the intracellular medium and the substrate. However, the harnessing of cell polarisation for motility requires substrate-mediated interactions. Motility can be optimised by adapting the oscillation frequency to the relaxation time of the system or when the substrate and cell viscosities match. Cellular noise can destroy mechanical coordination between force-generating elements within the cell, resulting in sudden changes of polarisation. The persistence of the cell's motion is found to depend on the cell size and the substrate viscosity. Within such a model, chemotactic guidance of cell motion is obtained by directionally modulating the persistence of motion, rather than by modulating the instantaneous cell velocity, in a way that resembles the run and tumble chemotaxis of bacteria.
description: 11 pages, 4 figures, accepted for publication in Phys. Rev. E
Towards Quantification of Assurance for Learning-enabled Components
Creators: name: Asaadi, Erfan
name: Denney, Ewen
name: Pai, Ganesh
Publisher: name: arXiv
Year: 2023
Subjects: subject: Software Engineering (cs.SE)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Perception, localization, planning, and control, high-level functions often organized in a so-called pipeline, are amongst the core building blocks of modern autonomous (ground, air, and underwater) vehicle architectures. These functions are increasingly being implemented using learning-enabled components (LECs), i.e., (software) components leveraging knowledge acquisition and learning processes such as deep learning. Providing quantified component-level assurance as part of a wider (dynamic) assurance case can be useful in supporting both pre-operational approval of LECs (e.g., by regulators), and runtime hazard mitigation, e.g., using assurance-based failover configurations. This paper develops a notion of assurance for LECs based on i) identifying the relevant dependability attributes, and ii) quantifying those attributes and the associated uncertainty, using probabilistic techniques. We give a practical grounding for our work using an example from the aviation domain: an autonomous taxiing capability for an unmanned aircraft system (UAS), focusing on the application of LECs as sensors in the perception function. We identify the applicable quantitative measures of assurance, and characterize the associated uncertainty using a non-parametric Bayesian approach, namely Gaussian process regression. We additionally discuss the relevance and contribution of LEC assurance to system-level assurance, the generalizability of our approach, and the associated challenges.
description: 8 pp, 4 figures, Appears in the proceedings of EDCC 2019
IMMUNOTHERAPY: THE EMERGING ARM OF ONCOLOGIC MANAGEMENT
Creators: name: K. Suresh
name: Ashok Kumar Gupta
name: Ramya Venkataraman
name: Vikram Singh Chauhan
Publisher: name: Zenodo
Year: 2023
Subjects: Immunotherapy, Role in Surgery

description: Abstract 
Oncology, the study of malignant tumors, has been a field of extensive research in all aspects of management including primary prevention which automatically evolved the concept of early diagnosis and better results in many cases. As research boomed, so evolved chemotherapy and the effort to reduce side effects succeeded however etiology and nutritional side effects needed more studies and efforts. The past decade has witnessed monumental progress in the treatment of malignancies with more specific and targeted therapies emerging, many holding a promise for providing a cure for cancer. At the forefront of these therapies is immunotherapy, which is fast changing the landscape of cancer medicine. It has joined ranks with chemotherapy, radiotherapy and surgery as the fourth arm of cancer treatment. Parallelly RNA and DNA analyses has contributed to familial tumours workup and therapeutic interventions. Very rapid strides have been put in place and immunotherapy as a modality of treatment is becoming a primary therapeutic choice for patients. Globally immunotherapy has been accepted and is evolving to make a difference in therapeutic outcomes in very many mitotic lesions. In this review we provide a brief history of the advent of immunotherapy and a detailed description of the different immunotherapeutic strategies that have emerged as key players in cancer treatment.
Leaky dust traps: How fragmentation impacts dust filtering by planets
Creators: name: Stammler, Sebastian Markus
name: Lichtenberg, Tim
name: Drążkowska, Joanna
name: Birnstiel, Tilman
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The nucleosynthetic isotope dichotomy between carbonaceous (CC) and non-carbonaceous (NC) meteorites has been interpreted as evidence for spatial separation and the coexistence of two distinct planet-forming reservoirs for several million years in the solar protoplanetary disk. The rapid formation of Jupiter's core within one million years after the formation of calcium-aluminium-rich inclusions (CAIs) has been suggested as a potential mechanism for spatial and temporal separation. In this scenario, Jupiter's core would open a gap in the disk and trap inward-drifting dust grains in the pressure bump at the outer edge of the gap, separating the inner and outer disk materials from each other. We performed simulations of dust particles in a protoplanetary disk with a gap opened by an early-formed Jupiter core, including dust growth and fragmentation as well as dust transport, using the dust evolution software DustPy. Our numerical experiments indicate that particles trapped in the outer edge of the gap rapidly fragment and are transported through the gap, contaminating the inner disk with outer disk material on a timescale that is inconsistent with the meteoritic record. This suggests that other processes must have initiated or at least contributed to the isotopic separation between the inner and outer Solar System.
description: Accepted for publication in Astronomy & Astrophysics Letters
Advances in the Implementation of the Exactly Energy Conserving Semi-Implicit (ECsim) Particle in Cell Method
Creators: name: Lapenta, Giovanni
Publisher: name: arXiv
Year: 2023
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The Energy Conserving semi-implicit method (ECsim), presented by Lapenta in 2017, is a Particle in Cell (PIC) algorithm for the simulation of plasmas. Energy conservation is achieved within a semi-implicit formulation that does not require any non-linear solver. A mass matrix is introduced to express linearly the particle-field coupling. With the mass matrix the algorithm preserves energy conservation to machine precision. The construction of the mass matrix is the central nature of the method and also the main cost of the computational cycle. We analyze here three methods that modify the construction of the mass matrix. First, we consider how the sub-cycling of the particle motion modifies the mass matrix. Second, we introduce a form of smoothing that reduces the noise while retaining exact energy conservation. Finally, we discuss an approximation of the mass matrix that transform the ECsim scheme to the implicit moment method.
Excitonic Spectra of Wide Parabolic Quantum Wells
Creators: name: Czajkowski, Gerard
name: Zielińska-Raczyńska, Sylwia
name: Ziemkiewicz, David
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The optical properties of wide Quantum Wells are considered, taking into account the screened electron-hole interaction potential and parabolic confinement potentials, different for the electrons and for the holes. The role of the interaction potential which mixes the energy states according to different quantum numbers is stressed. The results obtained by our method are in agreement with the observed spectra and give the possibility to the assessment of the resonances.
description: 13 pages, 7 figures typos corrected