cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The first reported outbreak of equine herpesvirus myeloencephalopathy in New Zealand
Creators: name: AMJ McFadden
name: D Hanlon
name: RK McKenzie
name: I Gibson
name: IM Bueno
name: DJ Pulford
name: D Orr
name: M Dunowska
name: WL Stanislawek
name: RP Spence
name: WL McDonald
name: G Munro
name: IG Mayhew
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: CASE HISTORY AND CLINICAL FINDINGS: On 9 January 2014 (Day 0) a mare from a stud farm in the Waikato region presented with urinary incontinence without pyrexia. Over the following 33 days 15 mares were clinically affected with neurological signs. All but one mare had a foal at foot. The most commonly observed clinical signs were hind limb paresis and ataxia. In some cases recumbency occurred very early in the course of disease and seven mares were subject to euthanasia for humane reasons. LABORATORY FINDINGS: Equid herpesvirus (EHV) type 1 was detected using PCR in various tissues collected post mortem from two mares with neurological signs. DNA sequencing data from the DNA polymerase gene of the virus showed a nucleotide transition at position 2254, a mutation encoding amino acid D752 that is highly associated with the neuropathogenic genotype of EHV-1. In total 12/15 mares were confirmed positive for EHV-1 on PCR. Results from a virus neutralisation test and ELISA on paired serum samples, and PCR on whole blood and nasal swabs, indicated that of four paddocks in a high-risk area where a cluster of cases had occurred, 20/21 (95%) horses were likely to have been exposed or were confirmed infected with EHV-1. Subsequent to the outbreak two mares aborted, one at 9 months and one at 10 months of gestation. The cause of abortion was confirmed as EHV-1 with the same genotype as that involved in the outbreak. DIAGNOSIS: Equine herpesvirus myeloencephalopathy. CLINICAL RELEVANCE: The outbreak described shows the considerable impact that can occur in outbreaks of equine herpesvirus myeloencephalopathy in New Zealand. Early biosecurity controls not only reduced the effect on the farm but mitigated the potential for the virus to spread to other horse enterprises.
title: On 3D fixed-angle chains that are locked, equilateral, equiangular, and obtuse
Creators: name: Lummerzheim, Jonas
Publisher: name: Hochschulbibliothek der Technischen Hochschule Köln
Year: 2022
Subjects: subject: 000 Allgemeines, Wissenschaft
subject: 510 Mathematik
subject: 530 Physik
subject: 540 Chemie
subject: 570 Biowissenschaften, Biologie

description: For most classes of chains, it is known if these contain locks, but especially for fixed-angle equilateral equiangular obtuse open polygonal chains in 3D, which can be used to model protein backbones, this is unknown. Fixed-angle equilateral equiangular obtuse closed and open polygonal chains can be used to model polymers. For these, it is clear, that locks based on knots exist, but not which chains are generally locked. We therefore examine both open and closed fixed-angle equilateral equiangular obtuse chains. For this purpose, those chains are divided into various subgroups and, depending on the subgroup, other aspects are investigated to show locks. Techniques from knot theory, graph theory, and specifically robot arm reachability and motion planning are combined. Algorithms are developed to create chains in desired configurations and to study them. It is shown why all fixed-angle equilateral equiangular obtuse closed chains are expected to be locked or in rare cases rigid and non-locked, but never non-locked and non-rigid. For fixed-angle equilateral equiangular obtuse open chains it is shown why it is expected that there are open chains that are locked and that the smallest locked open chain has 𝑛=7.
Comparision of Biological Activities of essential oil of  three Gymnosperms against Salmonella typhimurium
Creators: name: Singh, Ravikant
name: Pathak, Ashutosh
name: Dikshit, Anupam
name: Mishra, Rohit Kumar
Publisher: name: Zenodo
Year: 2018

description: The present investigation were focused on the comparision of biological activities of the essential oil of the three gymnospermous foliages i.e., Pinus roxburghii Sarg., Taxodium distichum L., and Thuja occidentalis L., against Salmonella typhimurium (MTCC- 3231). The oils were extracted from the needles and foliages of aforementioned plant species using hydro-distillation method. The antibacterial activity of the extracted essential oils was evaluated against Salmonella typhimurium (MTCC- 3231) using broth micro-dilution method recommended by Clinical Laboratory Standards Institute (CLSI). The Inhibition Concentration i.e. IC50 and Minimum Inhibition concentrations (MIC) using SpectramaxPlus384, of Molecular Devices Corporation, USA were recorded while Streptomycin as standard was taken. The IC50 value of P. roxburghii, T. distichum and T. occidentalis were showed 0.788, 0.064 and 1.135 mg/ml respectively. The T. distichum was found most effective with their MIC 0.353 mg/ml while T. occidentalis found least effective with their MIC 1.629 mg/ml against S. typhimurium. Hence, essential oil from foliages and needles of gymnosperms exhibit great potential for the development of eco-friendly, non-toxic, cost effective anti-bacterial formulations after undergoing detailed investigation which is in progress.
title: Configuration of energy transition factors in Inner Mongolia: A qualitative fuzzy logic approach
Creators: name: Zhang, Jinghong
Publisher: name: Hochschulbibliothek der Technischen Hochschule Köln
Year: 2022
Subjects: subject: 300 Sozialwissenschaften

description: Transitioning towards a low-carbon society is now increasingly becoming a global concern. The goal of successfully achieving this energy transition has become one of most pressing challenge, both among government decision makers and academia. Energy transition has raised up and become one of the top action priorities in China. Inner Mongolia, as the study area in this research, is significant in China's energy transition as one of leading provinces in terms of energy resources and electricity outward transmission. The main goal of this dissertation is to identify configurations that influence on the energy transition in IMAR. On the basis of a multilevel perspective (MLP) framework, the method of fuzzy-set qualitative comparative analysis (fsQCA) is applied within the thesis, taking 8 Chinese municipalities or leagues as study cases. A qualitative comparative study is carried out of configurations of diversified factors, which affect China’s energy transition. Eight antecedent conditions extracted from landscape level, regime level and niche level respectively. It is shown that different transition trajectories can have a similar energy transition outcome. Energy transition itself is induced by multiple factors collaboratively. Coal resource curse does not always have negative effects on energy transition in Inner Mongolia. Within this work, two main energy transition modes (supply and demand balance reversed mode in western IMAR and energy technological transformation mode in eastern IMAR) are constructed based on regional differences and yearly dynamics, illustrating the trajectories with different municipal characteristics. The transition pattern also shows different geographical characteristics. Different east-west distribution of the electricity market distributes differently in eastern and western Inner Mongolia, however, the difference in distinct forms of electricity market does not show enough impact on the energy transition trajectory in this dissertation. Overall, this study shows that the local response and its effects on the process of energy transition, in the light of the encouragement and advocacy by the central government. Meanwhile, this study offers a deeper understanding in the feasibility of the application with a methodological combination of MLP and fsQCA in provincial level for future research.
Perturbation Towards Easy Samples Improves Targeted Adversarial Transferability
Creators: name: Gao, Junqi
name: Qi, Biqing
name: Li, Yao
name: Guo, Zhichang
name: Li, Dong
name: Xing, Yuming
name: Zhang, Dazhi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: The transferability of adversarial perturbations provides an effective shortcut for black-box attacks. Targeted perturbations have greater practicality but are more difficult to transfer between models. In this paper, we experimentally and theoretically demonstrated that neural networks trained on the same dataset have more consistent performance in High-Sample-Density-Regions (HSDR) of each class instead of low sample density regions. Therefore, in the target setting, adding perturbations towards HSDR of the target class is more effective in improving transferability. However, density estimation is challenging in high-dimensional scenarios. Further theoretical and experimental verification demonstrates that easy samples with low loss are more likely to be located in HSDR. Perturbations towards such easy samples in the target class can avoid density estimation for HSDR location. Based on the above facts, we verified that adding perturbations to easy samples in the target class improves targeted adversarial transferability of existing attack methods. A generative targeted attack strategy named Easy Sample Matching Attack (ESMA) is proposed, which has a higher success rate for targeted attacks and outperforms the SOTA generative method. Moreover, ESMA requires only 5% of the storage space and much less computation time comparing to the current SOTA, as ESMA attacks all classes with only one model instead of seperate models for each class. Our code is available at https://github.com/gjq100/ESMA.
title: Wertschätzen im Teamteaching – Operatoren zur Wirksamkeit
Creators: name: Bauer, Laura
name: Rohr, Dirk
Year: 2022
Subjects: subject: 370 Erziehung, Schul- und Bildungswesen

description: Der Fokus dieses Artikels liegt auf den zwischenmenschlichen Herausforderungen und Dynamiken, die dem Teamteaching, bspw. in Form eines Lehr-Duos in der Praxis immanent sind. Hierbei wiederum liegt der Schwerpunkt der Untersuchung auf einer lösungsorientierten Perspektive. Der Hypothese folgend, dass Wertschätzung ein elementarer Faktor interdisziplinärer Lehre ist, wird diese definitorisch, konzeptionell und theoretisch beleuchtet. Hier ergibt sich die Korrelation der professionellen und der persönlichen Ebene als wichtiges Merkmal der Wertschätzung im Teamteaching.
description: Forschung und Innovation in der Hochschulbildung; 13
Autophagy supports color vision
Creators: name: Zhenqing Zhou
name: Vinberg, Frans
name: Schottler, Frank
name: Doggett, Teresa A
name: Kefalov, Vladimir J
name: Ferguson, Thomas A
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Cones comprise only a small portion of the photoreceptors in mammalian retinas. However, cones are vital for color vision and visual perception, and their loss severely diminishes the quality of life for patients with retinal degenerative diseases. Cones function in bright light and have higher demand for energy than rods; yet, the mechanisms that support the energy requirements of cones are poorly understood. One such pathway that potentially could sustain cones under basal and stress conditions is macroautophagy. We addressed the role of macroautophagy in cones by examining how the genetic block of this pathway affects the structural integrity, survival, and function of these neurons. We found that macroautophagy was not detectable in cones under normal conditions but was readily observed following 24 h of fasting. Consistent with this, starvation induced phosphorylation of AMPK specifically in cones indicating cellular starvation. Inhibiting macroautophagy in cones by deleting the essential macroautophagy gene Atg5 led to reduced cone function following starvation suggesting that cones are sensitive to systemic changes in nutrients and activate macroautophagy to maintain their function. ATG5-deficiency rendered cones susceptible to light-induced damage and caused accumulation of damaged mitochondria in the inner segments, shortening of the outer segments, and degeneration of all cone types, revealing the importance of mitophagy in supporting cone metabolic needs. Our results demonstrate that macroautophagy supports the function and long-term survival of cones providing for their unique metabolic requirements and resistance to stress. Targeting macroautophagy has the potential to preserve cone-mediated vision during retinal degenerative diseases.
Autophagy supports color vision
Creators: name: Zhenqing Zhou
name: Vinberg, Frans
name: Schottler, Frank
name: Doggett, Teresa A
name: Kefalov, Vladimir J
name: Ferguson, Thomas A
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Physiology
subject: Neuroscience
subject: Genetics
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: Cones comprise only a small portion of the photoreceptors in mammalian retinas. However, cones are vital for color vision and visual perception, and their loss severely diminishes the quality of life for patients with retinal degenerative diseases. Cones function in bright light and have higher demand for energy than rods; yet, the mechanisms that support the energy requirements of cones are poorly understood. One such pathway that potentially could sustain cones under basal and stress conditions is macroautophagy. We addressed the role of macroautophagy in cones by examining how the genetic block of this pathway affects the structural integrity, survival, and function of these neurons. We found that macroautophagy was not detectable in cones under normal conditions but was readily observed following 24 h of fasting. Consistent with this, starvation induced phosphorylation of AMPK specifically in cones indicating cellular starvation. Inhibiting macroautophagy in cones by deleting the essential macroautophagy gene Atg5 led to reduced cone function following starvation suggesting that cones are sensitive to systemic changes in nutrients and activate macroautophagy to maintain their function. ATG5-deficiency rendered cones susceptible to light-induced damage and caused accumulation of damaged mitochondria in the inner segments, shortening of the outer segments, and degeneration of all cone types, revealing the importance of mitophagy in supporting cone metabolic needs. Our results demonstrate that macroautophagy supports the function and long-term survival of cones providing for their unique metabolic requirements and resistance to stress. Targeting macroautophagy has the potential to preserve cone-mediated vision during retinal degenerative diseases.
Dehydrative Annulation Strategy for the Construction of Octahydroindolizine Framework: A Diastereoselective Synthesis of (6R, 8aS)-Octahydroindolizin-6-ol
Creators: name: Subbarao Jammula
name: Venkateswara Rao Anna
name: Sandip R. Khobare
name: U. K. Syam Kumar
name: Bagineni Prasad
name: Manojit Pal
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Information and Computing Sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Molecular Biology
subject: Microbiology
subject: Biochemistry

description: A dehydrative annulation strategy involving an intramolecular ring closure under a Mitsunobu type reaction condition has been used for the construction of octahydroindolizine framework successfully. This strategy that was reported to be unsuccessful when applied to a similar other system allowed us to perform a diastereoselective synthesis of (6R, 8aS)-octahydroindolizin-6-ol [a precursor of (-)-8a-epidesacetoxyslaframine] starting from commercially available chiral (S)-epichlorohydrin via a piperidine intermediate i.e., (3R, 6S)-6-(3-hydroxypropyl)piperidin-3-ol. The methodology has potential to afford a library of optically pure small molecules of pharmacological importance based on the related indolizine framework.
title: One Slide About – Leicht verdauliche Häppchen oder doch Happen?
Creators: name: Knaut, Carsten
Year: 2022
Subjects: subject: 370 Erziehung, Schul- und Bildungswesen

description: Ob Tweet, TikTok-Video oder Elevator Pitch – Informationen pointiert zu verdichten entwickelt sich zur Kunst. Das Format One Slide About (nachfolgend OSA) fordert Kursteilnehmer*innen auf, ein Thema oder eine wissenschaftliche Studie auf einem einzelnen Slide einer Präsentation zu verdichten und diesen den Kommiliton*innen in einem max. 180 Sekunden langen Vortrag vorzustellen. Dieses Format wurde in unterschiedlicher Umsetzung erprobt, mit den Teilnehmer*innen diskutiert und anschließend in Form einer quantitativen Befragung unter folgender Forschungsfragestellung evaluiert: Lässt sich mit dem Format One Slide About sowohl Informationskompetenz üben als auch eine Lehrveranstaltung inhaltlich ergänzen?
description: Forschung und Innovation in der Hochschulbildung; 12
Bird fruit consumption results from the interaction between fruit-handling behaviour and fruit crop size
Creators: name: F.X. Palacio
name: M. Valoy
name: F. Bernacki
name: M.S. Sánchez
name: M.G. Núñez-Montellano
name: O. Varela
name: M. Ordano
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology

description: Bird foraging behaviour is a major factor involved in mutualistic interactions of fleshy-fruited plants. Despite much research, we still lack quantified demonstrations of how fruit display traits affect fruit removal behaviour. Although the fruit crop size hypothesis proposes a general mechanism for fruit trait selection, it overlooks the fact that distinctive bird behaviours in a bird assemblage would have different effects on fruit crop size. Here, we show that the relevance of fruit crop size for bird fruit consumption is driven by two basic components of fruit foraging behaviour: fruit handling and residence time. We assessed bird fruit-eating behaviour (fruit consumption, fruit handling and residence time) and its relationship with fruit crop size, taking into account body size and spatial focal context (conspecific neighbour density and distance to the forest edge from individual plants) in a population of Vassobia breviflora (Solanaceae) in Tucumán, Argentina. At the assemblage level, fruit consumption was positively related to fruit crop size and residence time, and the interaction between fruit crop size and residence time depended on fruit-handling behaviour. At the functional group level, both gulpers and pulp consumers showed a positive relationship between fruit consumption and residence time. However, gulpers showed a negative interaction between fruit crop size and residence time, while pulp consumers showed no interaction. At the species level, fruit consumption by Turdus rufiventris (gulper) was positively related to fruit crop size, whereas fruit consumption by Thraupis sayaca and Zonotrichia capensis (pulp consumers) depended positively on residence time. Essentially, gulpers spent short residence times in plants with larger fruit crops, whereas pulp consumers spent long residence times in plants regardless of fruit crop size. The segregation between fruit-eating behaviours and their relationship with fruit crop size suggests that bird functional groups (i.e. gulpers and pulp consumers) would shape fruit display traits with different intensities.
The first reported outbreak of equine herpesvirus myeloencephalopathy in New Zealand
Creators: name: AMJ McFadden
name: D Hanlon
name: RK McKenzie
name: I Gibson
name: IM Bueno
name: DJ Pulford
name: D Orr
name: M Dunowska
name: WL Stanislawek
name: RP Spence
name: WL McDonald
name: G Munro
name: IG Mayhew
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: Cancer
subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Neuroscience
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Medicine

description: CASE HISTORY AND CLINICAL FINDINGS: On 9 January 2014 (Day 0) a mare from a stud farm in the Waikato region presented with urinary incontinence without pyrexia. Over the following 33 days 15 mares were clinically affected with neurological signs. All but one mare had a foal at foot. The most commonly observed clinical signs were hind limb paresis and ataxia. In some cases recumbency occurred very early in the course of disease and seven mares were subject to euthanasia for humane reasons.LABORATORY FINDINGS: Equid herpesvirus (EHV) type 1 was detected using PCR in various tissues collected post mortem from two mares with neurological signs. DNA sequencing data from the DNA polymerase gene of the virus showed a nucleotide transition at position 2254, a mutation encoding amino acid D752 that is highly-associated with the neuropathogenic genotype of EHV-1. In total 12/15 mares were confirmed positive for EHV-1 on PCR. Results from a virus neutralisation test and ELISA on paired serum samples, and PCR on whole blood and nasal swabs, indicated that of four paddocks in a high risk area where a cluster of cases had occurred, 20/21 (95%) horses were likely to have been exposed or were confirmed infected with EHV-1. Subsequent to the outbreak two mares aborted, one at 9 months and one at 10 months of gestation. The cause of abortion was confirmed as EHV-1 with the same genotype as that involved in the outbreak.DIAGNOSIS: Equine herpesvirus myeloencephalopathy.CLINICAL RELEVANCE: The outbreak described shows the considerable impact that can occur in outbreaks of equine herpesvirus myeloencephalopathy in New Zealand. Early biosecurity controls not only reduced the effect on the farm but mitigated the potential for the virus to spread to other horse enterprises.McFadden_Supp_Information.pdf
title: Biophysical and cellular insights into the membrane insertion mechanism of CLIC1
Creators: name: Hendry, Alexandra Christina
Publisher: name: University of Kent
Year: 2022

description: Chloride intracellular channel 1 (CLIC1) is a human protein expressed in the cytosol that has a remarkable feature – it can transition into an active chloride channel in nuclear, endoplasmic reticulum or plasma membranes. This metamorphic nature makes CLIC1 a potential drug target as overexpression of the membrane channel form in cells is implicated in neurodegenerative disease progression and tumour proliferation especially in cancers with poor prognosis such as glioblastomas. The mechanism of CLIC1 activation and membrane insertion, as well as the oligomerisation state and structure of the channel, still remain elusive, therefore my PhD focuses on deciphering more information about how and why CLIC1 forms a chloride channel. Combining biophysical and microscopy techniques we have discovered that, upon binding to divalent cations Ca2+ and Zn2+, CLIC1 relocalises and inserts into the plasma membrane to form an active chloride channel in both in vitro and in vivo experiments. Previous literature heavily implicates the role of cysteine oxidation in CLIC1 channel formation but the use of solution NMR studies confirmed that both the soluble and membrane bound forms of CLIC1 are in the same oxidation state, further supporting the hypothesis divalent cations are the trigger for this translocation from a cytosolic globular protein to integral membrane chloride channel. The identification of the molecular switch that promotes CLIC1 membrane insertion is a significant discovery as it provides a model that can enable mechanistic studies of CLIC1 translocation and structural investigation of the channel form, known to have clinical relevance. Additional research focused on how CLIC1 interacts with divalent cations in a cellular environment aiming to elucidate information about the conformational changes the protein undergoes in vivo.
Effectiveness of Government Policies on Primary  Education in Prayagraj Region
Creators: name: Ruchi Singh
Publisher: name: Zenodo
Year: 2024

description: This study evaluates the effectiveness of government policies on primary education in the Prayagraj region, focusing

on the implementation and impact of the Right to Education (RTE) Act and the Mid-Day Meal Scheme. Data were

collected from 10 government primary schools through surveys, interviews with teachers and administrators, and

official records spanning 2018–2023. The study revealed a 23% increase in enrollment rates following the

implementation of these policies, with significant gains observed among marginalized groups, including Scheduled

Castes and Scheduled Tribes. Retention rates also improved by 18%, attributed to the incentives provided under the

Mid-Day Meal Scheme and infrastructural improvements mandated by RTE.

However, challenges persist. Approximately 15% of schools reported delays in receiving funds, affecting the quality

of meals and infrastructure maintenance. Teacher-pupil ratios remained suboptimal in 40% of the schools,

highlighting the need for better resource allocation. The qualitative data suggest that while these policies have

reduced dropouts, the lack of parental awareness and socio-economic barriers continue to hinder their full impact.

The study concludes that government interventions have positively influenced primary education outcomes in

Prayagraj, but structural and administrative inefficiencies must be addressed for sustained improvements.

Recommendations include timely disbursement of funds, community engagement to raise awareness, and enhanced

monitoring mechanisms. These measures could further improve enrollment and retention rates, ensuring inclusive

and equitable education for all children in the region.
Role of future scenarios in understanding deep uncertainty in long-term air quality management
Creators: name: Gamas, Julia
name: Dodder, Rebecca
name: Loughlin, Dan
name: Gage, Cynthia
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Engineering

description: The environment and its interactions with human systems, whether economic, social, or political, are complex. Relevant drivers may disrupt system dynamics in unforeseen ways, making it difficult to predict future conditions. This kind of “deep uncertainty” presents a challenge to organizations faced with making decisions about the future, including those involved in air quality management. Scenario Planning is a structured process that involves the development of narratives describing alternative future states of the world, designed to differ with respect to the most critical and uncertain drivers. The resulting scenarios are then used to understand the consequences of those futures and to prepare for them with robust management strategies. We demonstrate a novel air quality management application of Scenario Planning. Through a series of workshops, important air quality drivers were identified. The most critical and uncertain drivers were found to be “technological development” and “change in societal paradigms.” These drivers were used as a basis to develop four distinct scenario storylines. The energy and emissions implications of each storyline were then modeled using the MARKAL energy system model. NOx emissions were found to decrease for all scenarios, largely a response to existing air quality regulations, whereas SO2 emissions ranged from 12% greater to 7% lower than 2015 emissions levels. Future-year emissions differed considerably from one scenario to another, however, with key differentiating factors being transition to cleaner fuels and energy demand reductions.Implications: Application of scenarios in air quality management provides a structured means of sifting through and understanding the dynamics of the many complex driving forces affecting future air quality. Further, scenarios provide a means to identify opportunities and challenges for future air quality management, as well as a platform for testing the efficacy and robustness of particular management options across wide-ranging conditions.
FAIRification of Services – Two Examples | 2nd FAIRsFAIR webinar
Creators: name: Behnke, Claudia
name: Koers, Hylke
Publisher: name: Zenodo
Year: 2020

description: Webinar official page: https://www.fairsfair.eu/events/fairification-services-%E2%80%93-two-examples The webinar is offered by FAIRsFAIR Work Package FAIR Practices: Semantics, Interoperability, and Services, and explores two facets of the FAIRification of services: the FAIR assessment framework for data services, and the features of FAIR repositories. The FAIR principles are explicitly targeted at both metadata and data, with data here being regarded as any digital resource, asset or object (e.g. APIs, workflows, ontologies, models, and others). However, digital objects cannot be made FAIR without supporting infrastructure services supporting the FAIR data principles themselves. One approach is a systematic evaluation of the FAIRness of services. In this regard, FAIRsFAIR is developing a FAIR assessment framework for data services alongside a similar framework for research software. The interim “Assessment report on ‘FAIRness of services" is the topic of the first part of the webinar. The webinar will briefly review FAIR assessment frameworks for data and other digital objects and motivate the need for a similar framework for services. In the second part, the focus is on repositories, which not only give access (with needed restrictions) to research data and metadata, but are searchable and offer persistent identifiers which enable search functionality. Deliverable 2.3 Set of FAIR data repositories features presents a list of the features of repositories which allow them not only to host FAIR digital objects but also to support the FAIR principles more fully. After the presentations there will be time for Q&A and discussion; all feedback on the underlying reports will be welcome at the webinar and can also be offered online at the links provided above.
The use and value of citizen science data in New Zealand
Creators: name: MA Peters
name: C Eames
name: D Hamilton
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Ecology
subject: FOS: Biological sciences

description: There has been significant growth worldwide of citizen science projects involving community members collecting environmental data. The following study is based on questionnaire responses from 296 community environmental groups and interviews with 34 project partners (e.g. resource managers and scientists) and examines the use and value of citizen science data in New Zealand. Frequency counts and inductive thematic analysis were used to examine the quantitative and qualitative data, respectively. Groups reported using their data to support funding applications (63%; n = 151), inform restoration management decision-making (60%; n = 151) and for educational purposes (48%; n = 157). Outcomes such as relationship-building with project partners and increasing environmental knowledge highlighted the transformational nature of groups’ citizen science activities. Although groups reported providing data to project partners (60%; n = 151), concerns were expressed over data quality and a lack of institutional systems for using the data. Project partners, however, proposed novel solutions for enhancing collaboration with groups to produce useful data, underscoring the value they attributed to groups’ citizen science efforts.
Pro OAR DE – Professionalisierung der Open-Access-Repositorien-Infrastruktur in Deutschland
Creators: name: Pampel, Heinz
name: Wrzesinski, Marcel
Publisher: name: Zenodo
Year: 2024
Subjects: Open Access
Open Access Repositories
Open Science

description: Presentation at the open-access.network Focus Group on Subject Repositories (open-access.network Fokusgruppe Fachrepositorien), 03/06/2024
Flexible work patterns and experiences of the work–family interface among Australian parents
Creators: name: Hokke, Stacey
name: Mason, Simon
name: Crawford, Sharinne
name: Cooklin, Amanda
name: Giallo, Rebecca
name: Bennetts, Shannon
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 350502
subject: Employment equity and diversity
classificationCode: 3505
subject: Human resources and industrial relations

description: Flexible work is often heralded as a key solution to the work–family ‘juggle’, yet evidence of its effectiveness is mixed, and few studies consider how parents combine flexible work options to balance work and care. This study aimed to examine the interplay between formal (employer-provided) and informal (self-directed) flexible work arrangements and identify usage patterns that support parents’ management of the work–family interface. We examined data from 3669 coupled Australian parents collected in 2016–2017. Using latent class analysis, we identified three distinct patterns of total flexibility use (low, moderate and high). Parents who were low users had the poorest work–family experiences, reporting higher work-to-family conflict, lower work–family enrichment and less balance than moderate or high users. However, high users experienced higher family-to-work conflict, and greater flexibility uptake did not ease perceptions of time pressure. Overall, findings demonstrate that formal and informal flexibility is a beneficial resource for mothers and fathers.
Role of future scenarios in understanding deep uncertainty in long-term air quality management
Creators: name: Gamas, Julia
name: Dodder, Rebecca
name: Loughlin, Dan
name: Gage, Cynthia
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Engineering

description: ABSTRACTThe environment and its interactions with human systems, whether economic, social or political, are complex. Relevant drivers may disrupt system dynamics in unforeseen ways, making it difficult to predict future conditions. This kind of “deep uncertainty” presents a challenge to organizations faced with making decisions about the future, including those involved in air quality management. Scenario Planning is a structured process that involves the development of narratives describing alternative future states of the world, designed to differ with respect to the most critical and uncertain drivers. The resulting scenarios are then used to understand the consequences of those futures and to prepare for them with robust management strategies. We demonstrate a novel air quality management application of Scenario Planning. Through a series of workshops, important air quality drivers were identified. The most critical and uncertain drivers were found to be “technological development” and “change in societal paradigms.” These drivers were used as a basis to develop four distinct scenario storylines. The energy and emissions implications of each storyline were then modeled using the MARKAL energy system model. NOX emissions were found to decrease for all scenarios, largely a response to existing air quality regulations whereas SO2 emissions ranged from 12% greater to 7% lower than 2015 emissions levels. Future-year emissions differed considerably from one scenario to another, however, with key differentiating factors being transition to cleaner fuels and energy demand reductions. IMPLICATIONSApplication of scenarios in air quality management provides a structured means of sifting through and understanding the dynamics of the many complex driving forces affecting future air quality. Further, scenarios provide a means to identify opportunities and challenges for future air quality management, as well as a platform for testing the efficacy and robustness of particular management options across wide-ranging conditions.
Dynamics of Transient Shock Waves in Detonation Engines
Creators: name: THETHY, BHAVRAJ SINGH
Publisher: name: Monash University
Year: 2022
Subjects: subject: Aerospace Engineering
subject: FOS: Mechanical engineering
subject: 91504 Fluidisation and Fluid Mechanics
subject: FOS: Other engineering and technologies

description: Replacing the combustion chamber of a gas turbine with a pulse-detonation combustor (PDC) is a means of drastically improving the efficiency of a gas turbine engine. The exhaust of a PDC contains fast-moving shock waves which are likely to damage other engine components and reduce the overall engine efficiency. The first part of the thesis focuses on the design and development of a facility for generating transient shock waves. The second part of the thesis presents three methods of attenuating the pressure fluctuations from the transient shock waves in order to maximise the efficiency of the engine.
Synthesis, ABTS-Radical Scavenging Activity, and Antiproliferative and Molecular Docking Studies of Novel Pyrrolo[1,2-a]quinoline Derivatives
Creators: name: Chandrika Nanjappa
name: Suresha Kumara T. Hanumanthappa
name: Gilish Jose
name: Kulkarni, Rashmi S.
name: Gopalpur Nagendrappa
name: Pasura Subbaiah Sujan Ganapathy
name: Shirur Dakappa Shruthi
name: More, Sunil S.
name: H. B. V. Sowmya
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Ecology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: A new 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS)-radical scavenging and antiproliferative agents of pyrrolo[1,2-a]quinoline derivatives have been synthesized. An efficient method for the synthesis of 14 novel diversified pyrrolo[1,2-a]quinoline derivatives has been described using 4-(1,3-dioxolan-2-yl)quinoline and different phenacyl bromides in acetone and followed by reacting with different acetylenes in dimethylformamide/K2CO3. The structure of the newly synthesized compounds was determined by infrared, 1H NMR, 13C NMR, mass spectrometry, and elemental analysis. The in vitro antioxidant activity revealed that among all the tested compounds 5n exhibited maximum scavenging activity with ABTS. Compound 5b has showed good antiproliferative activity as an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
Postoperative atrial fibrillation in patients undergoing non-cardiac non-thoracic surgery: A practical approach for the hospitalist
Creators: name: Joshi, Kirti K.
name: Tiru, Mihaela
name: Chin, Thomas
name: Marshal T. Fox
name: Stefan, Mihaela S.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Medicine

description: New postoperative atrial fibrillation (POAF) is the most common perioperative arrhythmia and its reported incidence ranges from 0.4 to 26% in patients undergoing non-cardiac non-thoracic surgery. The incidence varies according to patient characteristics such as age, presence of structural heart disease and other co-morbidities, as well as the type of surgery performed. POAF occurs as a consequence of adrenergic stimulation, systemic inflammation, or autonomic activation in the intra or postoperative period (e.g. due to pain, hypotension, infection) in the setting of a susceptible myocardium and other predisposing factors (e.g. electrolyte abnormalities). POAF develops between day 1 and day 4 post-surgery and it is often considered a self-limited entity. Its acute management involves many of the same strategies used in non-surgical patients but the optimal long-term management is challenging because of the limited available evidence. Several studies have shown an association between occurrence of POAF and in-hospital morbidity, mortality, and length of stay. Although, traditionally, POAF was considered to have a generally favorable long-term prognosis, recent data have shown an association with an increased risk of stroke at 1 year after hospitalization. It is unknown, however, whether strategies to prevent POAF or for rate/rhythm control when it does occur, lead to a reduction in morbidity or mortality. This suggests the need for future studies to better understand the risks associated with POAF and to determine optimal strategies to minimize long-term thromboembolic risks. In this article, we summarize the current knowledge on epidemiology, pathophysiology, and short- and long-term management of POAF after non-cardiac non-thoracic surgery with the goal of providing a practical approach to managing these patients for the non-cardiologist clinician.
Is European integration causing Europe to become more nationalist? Evidence from the 2007–9 financial crisis
Creators: name: Polyakova, Alina
name: Fligstein, Neil
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 111714 Mental Health
subject: Science Policy
subject: Cancer
subject: Sociology
subject: FOS: Sociology
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Medicine

description: ABSTRACTThe European Union's (EU) political and economic integration project has grown dramatically since its inception in 1952. While the ultimate goal of the EU is unclear, one of its aspirations has been to attempt to create European citizens. The idea is that over time, citizens would look towards Europe as their main national identity. While the political and economic integration projects are quite far along, the national identity project has lagged far behind. The number of people who have primarily a European identity is quite small and has not increased much in the past 20 years. There is a far larger number of citizens for whom their national identity is paramount, but a European identity also exists. Since 2005, this group has grown smaller and the number of citizens with only a national identity has grown larger. This article argues that the EU integration project has pushed citizens to value their national identities more and to look to their national governments to protect them. We examine the evidence for this in the context of the 2007–9 financial crisis. We show that in countries most seriously hit by the crisis, national identities have increased dramatically and citizens with some European identity have decreased.
Schritt für Schritt in den Open Access. Eine Handreichung für wissenschaftliche Fachgesellschaften
Creators: name: Rücknagel, Jesko
name: Martin, Linda
name: Schultze-Motel, Paul
name: Dellmann, Sarah
name: Neufend, Maike
name: Bruch, Christoph
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Open Access Publishing

description: Diese Handreichung wurde im Rahmen des BMBF-geförderten Projekts open-access.network entwickelt und richtet sich an Vorstände, Geschäftsstellen und Mitglieder wissenschaftlicher Fachgesellschaften. Sie bietet praxisnahe Empfehlungen für die Umsetzung der Open-Access-Transformation. Grundlage sind Auswertungen von Gesprächen und Workshops mit Vertreter*innen verschiedener Fachgesellschaften. Die beschriebenen Handlungsfelder und Strategien zeigen konkrete Ansätze auf und werden durch Beispiele ergänzt, die mögliche Wege zur Einführung und Förderung von Open Access illustrieren.
description: Die Version 1.0 dieser Publikation ist im Rahmen des Verbundprojekts „open-access.network 2“ erstellt und vom Bundesministerium für Bildung und Forschung ge­fördert worden (Förderkennzeichen: 16KUV014, 16KUV012, 16KUV013).
Synthesis, ABTS-Radical Scavenging Activity, and Antiproliferative and Molecular Docking Studies of Novel Pyrrolo[1,2-a]quinoline Derivatives
Creators: name: Chandrika Nanjappa
name: Suresha Kumara T. Hanumanthappa
name: Gilish Jose
name: Kulkarni, Rashmi S.
name: Gopalpur Nagendrappa
name: Pasura Subbaiah Sujan Ganapathy
name: Shirur Dakappa Shruthi
name: More, Sunil S.
name: H. B. V. Sowmya
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Ecology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: A new ABTS-radical scavenging and antiproliferative agents of pyrrolo[1,2-a]quinoline derivatives have been synthesized. An efficient method for the synthesis of fourteen novel diversified pyrrolo[1,2-a]quinoline derivatives has been described using 4-(1,3-dioxolan-2-yl)quinoline and different phenacyl bromides in acetone and followed by reacting with different acetylenes in DMF/K2CO3. The structure of the newly synthesized compounds was determined by IR, 1H NMR, 13C NMR, mass spectrometry and elemental analysis. The in vitro antioxidant activity revealed that, among all the tested compounds 5n has exhibited maximum scavenging activity with ABTS. The compound 5b has showed good antiproliferative activity as good inhibitor of EGFR tyrosine kinase.
Pandian: Neue Geschichte
Creators: name: Pandian, M.S.S.
name: Dhamotharan, Mohan
name: Pabst, Sabine
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 4-5 (1997): 1947-1997: 50 Jahre Unabhängigkeit
Satyagraha- Das Festhalten an der Wahrheit M.K. Gandhis Ethik der Gewaltfreiheit
Creators: name: Jürgenmeyer, Clemens
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 4-5 (1997): 1947-1997: 50 Jahre Unabhängigkeit
Von »Kritik« zu »Engagement durch Experimentalismus«
Creators: name: Lehmann, Damaris
Publisher: name: Universitätsbibliothek Siegen
Year: 2021
Subjects: subject: 100 Philosophie und Psychologie
subject: Experimentalismus
subject: Soziologie der Kritik
subject: Wissenschafts- und Technikforschung
subject: Pragmatistische Philosophie
subject: Soziale Erkenntnistheorie
subject: Empirie
subject: Pragmatismus
subject: Kritik

description: In diesem Beitrag wird die Frage nach dem Verhältnis Soziologie-Kritik und der Ausgestaltung dieses Verhältnisses diskutiert. Es werden diejenigen Prozesse näher betrachtet, die zu einer Transformation soziologischer Kritik geführt haben, und das Potenzial neuer Formen der Kritik herausgearbeitet. Dazu gehören in erster Linie Ansätze der Soziologie der Kritik und Experimentalismen soziologischer Prägung, so wie sie in der Wissenschafts- und Technikforschung einen Niedersatz finden.