cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Grounded by values: An emergent engineering practice
Creators: name: Coddington, Alicen
name: Mann, Llew
name: Chandrasekaran, Sivachandran
name: Cook, Emily
name: Crossin, Enda
name: Daniel, Scott
name: Mazzurco, Andrea
name: Smith, Tim
name: Turner, Jennifer
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 3901
subject: Curriculum and pedagogy
classificationCode: 390303
subject: Higher education
classificationCode: 401003
subject: Engineering practice

description: CONTEXT A transformational change in engineering education culture is required to address ongoing issues such as declining interest and a lack of diversity in the student cohorts and profession. This change must go beyond transforming educational pedagogies; organisational cultural change is necessary to shape perceptions about engineering and engineering in society. The creation of the Engineering Practice Academy at Swinburne University of Technology provides the opportunity to intentionally construct a culture guided by a set of espoused values that can be used to define and guide the emergent culture, and inform decisions made in the development of the Engineering Practice Academy. PURPOSE This paper describes the development process of co-constructing espoused values within the Engineering Practice Academy. APPROACH Espoused values were co-constructed by project stakeholders through a facilitated workshop. The workshops included individual tasks, reflections and sharing, and collective discussion used to facilitate the construction of the values. RESULTS The five espoused values co-constructed by project stakeholders were: collaboration with empathy, honesty through transparency, equity and diversity, sustainability through practice and, excellence – individually and collectively. The espoused values are being used in all aspects of the Academy’s creation such as evaluating and selecting potential initiatives, generating an ethical partnership policy to guide the selection of external partners and creating a culture to attract and support a diverse staff and student cohort. CONCLUSION Values-based decision making has been shown to empower individuals from all levels of an organisation to make decisions as well as being useful in the recruitment and retention of staff and students. Values present a novel resource for informing collaboration between Universities, industries, and community.
A survey of the biodiversity of Tunicata with a focus on Ascidiacea in the waters of Heligoland Island, North Sea
Creators: name: Gordetckaia, Olga
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: tunicates
subject: species distribution
subject: biodiversity survey
subject: Heligoland archipelago
subject: 570 Biologie

description: During a comprehensive study of the biodiversity of marine invertebrates on the island of Heligoland in September 2023, I identified 14 species of tunicates. I observed that some of these species occur only in specific locations on the island during this period and This agrees well with the results of previous studies on the distribution of species in different locations on the island. I suggest, that Molgula manhattensis is a relatively recently introduced species in this region.
Tissue time course and bioavailability of the pyrethroid insecticide bifenthrin in the Long-Evans rat
Creators: name: Hughes, Michael F.
name: Ross, David G.
name: Edwards, Brenda C.
name: DeVito, Michael J.
name: Starr, James M.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: 1. Pyrethroids are neurotoxic and parent pyrethroid appears to be toxic entity. This study evaluated the oral disposition and bioavailability of bifenthrin in the adult male Long-Evans rat. 2. In the disposition study, rats were administered bifenthrin (0.3 or 3 mg/kg) by oral gavage and serially sacrificed (0.25 h to 21 days). Blood, liver, brain and adipose tissue were removed. In the bioavailability study, blood was collected serially from jugular vein cannulated rats (0.25 to 24 h) following oral (0.3 or 3 mg/kg) or intravenous (0.3 mg/kg) administration of bifenthrin. Tissues were extracted and analyzed for bifenthrin by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). 3. Bifenthrin concentration in blood and liver peaked 1–2-h postoral administration and were approximately 90 ng/ml (or g) and 1000 ng/ml (or g) for both tissues at 0.3 and 3 mg/kg, respectively. Bifenthrin was rapidly cleared from both blood and liver. Brain concentrations peaked at 4–6 h and were lower than in blood at both doses (12 and 143 ng/g). Bifenthrin in adipose tissue peaked at the collected time points of 8 (157 ng/g) and 24 (1145 ng/g) h for the 0.3 and 3 mg/kg doses, respectively and was retained 21 days postoral administration. Following intravenous administration, the blood bifenthrin concentration decreased bi-exponentially, with a distribution half-life of 0.2 h and an elimination half-life of 8 h. Bifenthrin bioavailability was approximately 30%. These disposition and kinetic bifenthrin data may decrease uncertainties in the risk assessment for this pyrethroid insecticide.
Tissue time course and bioavailability of the pyrethroid insecticide bifenthrin in the Long-Evans rat
Creators: name: Hughes, Michael F.
name: Ross, David G.
name: Edwards, Brenda C.
name: DeVito, Michael J.
name: Starr, James M.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: 1. Pyrethroids are neurotoxic and parent pyrethroid appears to be toxic entity. This study evaluated the oral disposition and bioavailability of bifenthrin in the adult male Long-Evans rat. 2. In the disposition study, rats were administered bifenthrin (0.3 or 3 mg/kg) by oral gavage and serially sacrificed (0.25 h to 21 days). Blood, liver, brain and adipose tissue were removed. In the bioavailability study, blood was collected serially from jugular vein cannulated rats (0.25 to 24 h) following oral (0.3 or 3 mg/kg) or intravenous (0.3 mg/kg) administration of bifenthrin. Tissues were extracted and analyzed for bifenthrin by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). 3. Bifenthrin concentration in blood and liver peaked 1–2-h postoral administration and were approximately 90 ng/ml (or g) and 1000 ng/ml (or g) for both tissues at 0.3 and 3 mg/kg, respectively. Bifenthrin was rapidly cleared from both blood and liver. Brain concentrations peaked at 4–6 h and were lower than in blood at both doses (12 and 143 ng/g). Bifenthrin in adipose tissue peaked at the collected time points of 8 (157 ng/g) and 24 (1145 ng/g) h for the 0.3 and 3 mg/kg doses, respectively and was retained 21 days postoral administration. Following intravenous administration, the blood bifenthrin concentration decreased bi-exponentially, with a distribution half-life of 0.2 h and an elimination half-life of 8 h. Bifenthrin bioavailability was approximately 30%. These disposition and kinetic bifenthrin data may decrease uncertainties in the risk assessment for this pyrethroid insecticide.
Retinal Histopathology in Eyes from a Patient with Stargardt disease caused by Compound Heterozygous ABCA4 Mutations
Creators: name: Bonilha, Vera L.
name: Rayborn, Mary E.
name: Bell, Brent A.
name: Marino, Meghan J.
name: Fishman, Gerald A.
name: Hollyfield, Joe G.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Developmental Biology
subject: Computational Biology

description: Background: The goal of this study was to define the histopathology of the retina in donor eyes from a patient with Stargardt disease (STGD1) due to compound mutations in the ABCA4 gene. Materials and Methods: Eyes were obtained from a 66-year-old female and fixed within 18 hours postmortem. The fundi of the posterior globes were evaluated with macroscopic, SLO and OCT imaging. The perifoveal and peripheral regions were processed for electron microscopy and immunocytochemistry using cell specific antibodies. Two age-similar normal eyes were used as controls. Prior ophthalmic examinations and genetic test results were also reviewed. Results: All imaging modalities showed scattered bone spicules in the peripheral retina. Atrophy of the RPE was present around the optic nerve as evidenced by the absence of SLO autofluorescence. Histology analysis showed a severely degenerated fovea with little evidence of any retinal layering or remaining RPE. The fovea was severely degenerated, with little evidence of any retinal cell layer, including the RPE. In contrast, retinal nuclear layers were present in the periphery. The perifoveal region contained few cones labeled with cone-specific antibodies; some rhodopsin-labeled cells, reactive glia labeled with GFAP; and decreased autofluorescence of the RPE. The fovea was free of cone-specific labeling, contained a few disorganized rhodopsin-labeled cells and showed substantial GFAP labeling and no autofluorescent material in the retina. The periphery displayed stubby cells labeled with cone-specific antibodies, decreased rhodopsin-labeled cells, increased GFAP staining, and autofluorescent granules in the RPE. Conclusions: The histopathology of the retina in this patient with Stargardt disease displayed a highly degenerated fovea. In all retinal locations studied, cones were more severely affected than rods.
Mobility behaviour and driving status of patients with mental disorders – an exploratory study
Creators: name: Brunnauer, Alexander
name: Buschert, Verena
name: Segmiller, Felix
name: Zwick, Sarah
name: Bufler, Johannes
name: Schmauss, Max
name: Messer, Thomas
name: Hans-Jürgen Möller
name: Frommberger, Ulrich
name: Bartl, Helga
name: Steinberg, Reinhard
name: Laux, Gerd
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background Driving is an important activity of daily life and an integral part of mobility. However, impact of mental illness on road mobility is widely unexplored. Method Driving status in 1497 psychiatric inpatients (PPs) and a clinical control group of 313 neurological inpatients (NPs) was investigated using a brief questionnaire. Results 67% of PPs (89% NPs) reported to have a valid driver's licence and 77% of them (92% NPs) reported to regularly use their cars. Within driver's license holders, patients with organic mental disorder (32%), substance dependence (37%) and psychotic disorder (40%) had the lowest proportion of current drivers. Higher educational qualification (odds ratio [OR] from 2.978 to 17.036) and being married/partnered (OR 3.049) or divorced (OR 4.840) significantly advanced the probability of possession of a driving license. Predictive factors for driving cessation were being female, an older age, drawing a pension and having an organic mental disease or schizophrenic disorder. Conclusion Mental disease has a negative impact on driving status and this is especially true for illnesses frequently being accompanied by distinct cognitive impairments. Factors predicting road mobility elucidate the strong relationship with psychosocial status indicating that recovery of driving competence should be an integral goal of treatment strategies.
XR4HUMAN D6.1: Identifying & selection of use cases on good practices in XR
Creators: name: Hokstad, Leif Martin
name: Prasolova-Førland, Ekaterina
name: Louka, Michael N.
name: Salazar, Mikel
name: Kadlubsky, Alina
name: Kumar Renganayagalu, Sathiya
name: Stephane, Lucas
Publisher: name: Zenodo
Year: 2023

description: ABSTRACT

This deliverable report presents findings from a survey exploring good practices and use cases for XR technologies. Experts identified several applications such as training, education, entertainment, and healthcare, emphasizing the importance of user experience, technology, and overall goals. However, they noted that current XR systems are largely inaccessible to individuals with vision loss, low stereoacuity, poor digital literacy, and motor or cognitive impairments. The results will inform a Delphi study for consensus on best practices and guide the development of an online platform and demonstrator sites across Europe.
Supporting Information for "Domain-topic models with chained dimensions: charting the evolution of a major oncology conference (1995-2017)"
Creators: name: Hannud Abdo, Alexandre
Publisher: name: Zenodo
Year: 2020
Subjects: science mapping
scientometrics
text mining
stochastic block model
hypergraph
history of oncology
clinical cancer research

description: File "S1 Sashimis" contains the interactive domain-topic maps and usage instructions. File "S2 Data" contains the domain-topic model data and usage instructions. See the README inside each archive for full description. Preprint of the paper: https://arxiv.org/abs/1912.13349
Differences in CO2 and N2O emission rates following crop residue incorporation with or without field burning: A case study of adzuki bean residue and wheat straw
Creators: name: Koga, Nobuhisa
name: Hayashi, Kentaro
name: Shimoda, Seiji
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: In the context of sustainable soil-quality management and mitigating global warming, the impacts of incorporating raw or field-burned adzuki bean (Vigna angularis (Willd.) Ohwi & Ohashi) and wheat (Triticum aestivum L.) straw residues on carbon dioxide (CO2) and nitrous oxide (N2O) emission rates from soil were assessed in an Andosol field in northern Japan. Losses of carbon (C) and nitrogen (N) in residue biomass during field burning were much greater from adzuki bean residue (98.6% of C and 98.1% of N) than from wheat straw (85.3% and 75.3%, respectively). Although we noted considerable inputs of carbon (499 ± 119 kg C ha–1) and nitrogen (5.97 ± 0.76 kg N ha–1) from burned wheat straw into the soil, neither CO2 nor N2O emission rates from soil (over 210 d) increased significantly after the incorporation of field-burned wheat straw. Thus, the field-burned wheat straw contained organic carbon fractions that were more resistant to decomposition in soil in comparison with the unburned wheat straw. Our results and previously reported rates of CO2, methane (CH4) and N2O emission during wheat straw burning showed that CO2-equivalent greenhouse gas emissions under raw residue incorporation were similar to or slightly higher than those under burned residue incorporation when emission rates were assessed during residue burning and after subsequent soil incorporation.
Differences in CO2 and N2O emission rates following crop residue incorporation with or without field burning: A case study of adzuki bean residue and wheat straw
Creators: name: Koga, Nobuhisa
name: Hayashi, Kentaro
name: Shimoda, Seiji
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: In the context of sustainable soil-quality management and mitigating global warming, the impacts of incorporating raw or field-burned adzuki bean (Vigna angularis (Willd.) Ohwi & Ohashi) and wheat (Triticum aestivum L.) straw residues on carbon dioxide (CO2) and nitrous oxide (N2O) emission rates from soil were assessed in an Andosol field in northern Japan. Losses of carbon (C) and nitrogen (N) in residue biomass during field burning were much greater from adzuki bean residue (98.6% of C and 98.1% of N) than from wheat straw (85.3% and 75.3%, respectively). Although we noted considerable inputs of carbon (499 ± 119 kg C ha–1) and nitrogen (5.97 ± 0.76 kg N ha–1) from burned wheat straw into the soil, neither CO2 nor N2O emission rates from soil (over 210 d) increased significantly after the incorporation of field-burned wheat straw. Thus, the field-burned wheat straw contained organic carbon fractions that were more resistant to decomposition in soil in comparison with the unburned wheat straw. Our results and previously reported rates of CO2, methane (CH4) and N2O emission during wheat straw burning showed that CO2-equivalent greenhouse gas emissions under raw residue incorporation were similar to or slightly higher than those under burned residue incorporation when emission rates were assessed during residue burning and after subsequent soil incorporation.
Code and Dataset for Moonshot: Optimizing Block Period and Commit Latency in Chain-Based Rotating Leader BFT
Creators: name: Doidge, Isaac James
Publisher: name: Zenodo
Year: 2024
Subjects: Blockchain
Distributed Systems
Consensus
Jolteon
Moonshot

description: This artifact contains the code and dataset for the DSN submission Moonshot: Optimizing Block Period and Commit Latency in Chain-Based Rotating Leader BFT (anonymously submitted to DSN 2024 under the pseudonym AnonProt). This artifact also supplements the pre-print, extended version of the paper, referenced in the Related Works. Please see the readme within for detailed information about the dataset and instructions for replicating the figures presented in the paper.
Transformation in engineering education
Creators: name: Huynh, Van Thanh
name: Chandrasekaran, Sivachandran
name: Long, John M.
name: Guo, Yufei
name: Gibson, Ian
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 3901
subject: Curriculum and pedagogy
classificationCode: 390303
subject: Higher education
classificationCode: 401003
subject: Engineering practice

description: CONTEXT A collaborative teaching program between Deakin University and Wuhan University of Science and Technology (WUST) is a particular realization of a learning and teaching transformation. The collaborative program aims to bring high-quality Australian curriculum standards to mechanical engineering students in Wuhan, China. To maintain collaborative teaching quality, the entire Deakin mechanical engineering program is transformed to the WUST collaborative program. PURPOSE This study focuses on the quality assurance of teaching in the collaborative program when the learning and teaching process happens outside Australia. When a Mechanical engineering program is offered at a different institution at a different time-span, it requires different learning and teaching support as well as educational settings. APPROACH To address the first problem of insufficient equipment, we developed experimental equipment that is portable to WUST. To tackle the problem of teaching approaches, we implemented flipped-classroom teaching where equipping students with selflearning skills is emphasised. Quantitative and qualitative questions were given to the students at the end of the trimester teaching to analyse students’ experiences and expectations on the implementation of new teaching styles. The outcome of this survey is then fed back to the improvement process of such new teaching styles for the future academic years of the collaborative program. RESULTS The analysed survey results give an insight into students’ perception of the new learning and teaching approaches. The initial results show the overwhelmingly positive reception of the project/design based approach. Obvious quantitative improvements that have been measured are as follows: Students’ involvement in classroom/lab activities is improved when compared to that of a previous year cohort with the same activity. The WUST students showed improvement in terms of following along the intensive teaching/learning schedule. CONCLUSIONS From the survey results, more than 90% of students agreed that the group-based practical activities were most helpful towards achieving the learning goals. The project/design-based learning activities have enhanced students learning capability of understanding practical/theoretical prospects in this course.
Molecular progress on the mapping and cloning of functional genes for blast disease in rice (Oryza sativa L.): current status and future considerations
Creators: name: S. Ashkani
name: M. Y. Rafii
name: M. Shabanimofrad
name: A. Ghasemzadeh
name: S. A. Ravanfar
name: M. A. Latif
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Hematology
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Biotechnology
subject: Genetics
subject: Medicine

description: Rice blast disease, which is caused by the fungal pathogen Magnaporthe oryzae, is a recurring problem in all rice-growing regions of the world. The use of resistance (R) genes in rice improvement breeding programmes has been considered to be one of the best options for crop protection and blast management. Alternatively, quantitative resistance conferred by quantitative trait loci (QTLs) is also a valuable resource for the improvement of rice disease resistance. In the past, intensive efforts have been made to identify major R-genes as well as QTLs for blast disease using molecular techniques. A review of bibliographic references shows over 100 blast resistance genes and a larger number of QTLs (∼500) that were mapped to the rice genome. Of the blast resistance genes, identified in different genotypes of rice, ∼22 have been cloned and characterized at the molecular level. In this review, we have summarized the reported rice blast resistance genes and QTLs for utilization in future molecular breeding programmes to introgress high-degree resistance or to pyramid R-genes in commercial cultivars that are susceptible to M. oryzae. The goal of this review is to provide an overview of the significant studies in order to update our understanding of the molecular progress on rice and M. oryzae. This information will assist rice breeders to improve the resistance to rice blast using marker-assisted selection which continues to be a priority for rice-breeding programmes.
Method for increasing the computation speed of an unsupervised learning approach for data clustering
Creators: name: Yuwono, Mitchell
name: Su, Steven W.
name: Moulton, Bruce
name: Nguyen, Hung
Publisher: name: Swinburne
Year: 2024

description: Clustering can be especially effective where the data is irregular, noisy and/or not differentiable. A major obstacle for many clustering techniques is that they are computationally expensive, hence limited to smaller data volume and dimension. We propose a lightweight swarm clustering solution called Rapid Centroid Estimation (RCE). Based on our experiments, RCE has significantly quickened optimization time of its predecessors, Particle Swarm Clustering (PSC) and Modified Particle Swarm Clustering (mPSC). Our experimental results show that on benchmark datasets, RCE produces generally better clusters compared to PSC, mPSC, K-means and Fuzzy C-means. Compared with K-means and Fuzzy C-means which produces clusters with 62% and 55% purities on average respectively, thyroid dataset has successfully clustered on average 71% purity in 14.3 seconds.
Search for human DNA topoisomerase II poisons in the group of 2,5-disubstituted-1,3,4-thiadiazoles
Creators: name: Plech, Tomasz
name: Kaproń, Barbara
name: Paneth, Agata
name: Wujec, Monika
name: Czarnomysy, Robert
name: Bielawska, Anna
name: Bielawski, Krzysztof
name: Trotsko, Nazar
name: Kuśmierz, Edyta
name: Paneth, Piotr
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Hematology
Cancer
Developmental Biology
Chemistry
Biotechnology
Pharmacology
Molecular Biology
Cell Biology
Physics
Biochemistry
Biophysics

description: A series of six 2,5-disubstituted 1,3,4-thiadiazole derivatives was synthesized and examined for cytotoxic activity in MCF-7 and MDA-MB-231 breast cancer cells. MTT assay confirmed that 2-(3-fluorophenylamino)-5-(3-hydroxyphenyl)-1,3,4-thiadiazole (2), 2-(4-bromophenylamino)-5-(2,4-dichlorophenyl)-1,3,4-thiadiazole (3), 2-(4-fluorophenylamino)-5-(2,4-dichlorophenyl)-1,3,4-thiadiazole (4), had ability to inhibit MCF-7 and MDA-MB-231 cells proliferation. The IC50 values for the mentioned compounds ranged between 120 and 160 μM (with respect to MCF-7 cells) and from 70 to 170 μM (with respect to MDA-MB-231 cells). It turned out, moreover, that compound 2 is a human topoisomerase II (topoII) catalytic inhibitor whereas the two other compounds (i.e. 3 and 4) are capable of stabilizing DNA-topoII cleavage complex and thus are topoII poisons.
THE STUDENT EXPERIENCE: SMARTPHONE APPLICATIONS AND VOCABULARY GROWTH
Creators: name: Sobirjonova, Zikriyoxonposhsha
name: Shamsiddinova, Dilafruz
Publisher: name: Zenodo
Year: 2025

description: Nowadays,170 mobile applications are frequently employed in higher education, particularly for learning English as a foreign language, because of their special qualities (such as portability, multimodality, interaction, or ubiquity). The approach to learning using smartphones and mobile apps is, on the one hand, particularly learner-centered in the sense of autonomous and individualized learning, as opposed to traditional classroom learning. This research examines the perceived utility and effectiveness of smartphone applications (apps) for vocabulary acquisition among Uzbek students. Employing a mixed-methods approach, utilizing an online survey and researcher observation, the study investigated the perspectives of English major students at the Uzbekistan State World Languages University (UzSWLU). The findings indicate a generally positive perception of smartphone applications' contribution to vocabulary development, attributed to their capacity to provide substantial vocabulary input. Furthermore, the study identified age and prior experience with app utilization as significant variables influencing students' evaluations of app efficacy in vocabulary learning.
Mobility behaviour and driving status of patients with mental disorders – an exploratory study
Creators: name: Bufler, Johannes
name: Hans-Jürgen Möller
name: Brunnauer, Alexander
name: Buschert, Verena
name: Segmiller, Felix
name: Zwick, Sarah
name: Schmauss, Max
name: Messer, Thomas
name: Frommberger, Ulrich
name: Bartl, Helga
name: Steinberg, Reinhard
name: Laux, Gerd
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Biotechnology

description: Background. Driving is an important activity of daily life and an integral part of mobility. However, impact of mental illness on road mobility is widely unexplored. Method. Driving status in 1497 psychiatric inpatients (PPs) and a clinical control group of 313 neurological inpatients (NPs) was investigated using a brief questionnaire. Results. 67% of PPs (89% NPs) reported to have a valid driver's licence and 77% of them (92% NPs) reported to regularly use their cars. Within driver's license holders, patients with organic mental disorder (32%), substance dependence (37%) and psychotic disorder (40%) had the lowest proportion of current drivers. Higher educational qualification (odds ratio [OR] from 2.978 to 17.036) and being married/partnered (OR 3.049) or divorced (OR 4.840) significantly advanced the probability of possession of a driving license. Predictive factors for driving cessation were being female, an older age, drawing a pension and having an organic mental disease or schizophrenic disorder. Conclusion. Mental disease has a negative impact on driving status and this is especially true for illnesses frequently being accompanied by distinct cognitive impairments. Factors predicting road mobility elucidate the strong relationship with psychosocial status indicating that recovery of driving competence should be an integral goal of treatment strategies.
Позиции Российской Федерации и Соединенных штатов Америки по вопросу реформирования организации Объединенных Наций: краткий сравнительный анализ
Creators: name: Щербаков Юрий Вадимович
name: Щербаков Максим Юрьевич
Publisher: name: Universum: общественные науки
Year: 2016
Subjects: МЕЖДУНАРОДНЫЕ ОТНОШЕНИЯ
ОРГАНИЗАЦИЯ ОБЪЕДИНЕННЫХ НАЦИЙ
ПОСТОЯННЫЕ ЧЛЕНЫ СОВЕТА БЕЗОПАСНОСТИ ООН
ПРИНЦИП ВЕТО
РЕФОРМА ООН
РОССИЯ
СОВЕТ БЕЗОПАСНОСТИ ООН
СТРУКТУРА СБ ООН
США
INTERNATIONAL RELATIONS
THE UNITED NATIONS
THE PERMANENT MEMBERS OF THE UN SECURITY COUNCIL
THE PRINCIPLE OF THE VETO
THE REFORM OF THE UN
RUSSIA
THE UN SECURITY COUNCIL
UN SC
USA

description: Вопросы увеличения числа постоянных членов Совета Безопасности ООН и отмены (корректировки) принципа вето на протяжении нескольких десятилетий вызывают дискуссию среди государственно-политических деятелей и экспертов разных стран. В статье рассматриваются позиции Российской Федерации и США по реформированию Совета. Также дается сравнительный анализ подходов двух постоянных членов Совета Безопасности к преобразованию главного органа ООН.
description: Questions of increasing the number of permanent members of the UN Security Council and the cancellation (amendments) of the veto principle during several decades provoke a discussion among public and political figures and experts from different countries. The article deals with the position of the Russian Federation and the United States concerning the Council restructuring. Also, a comparative analysis of approaches of two permanent Security Council members is presented to the transformation of the main UN body.
Effectiveness of Xenon as a Fire Suppressant Under Microgravity Combustion Environment
Creators: name: Alam, Fahd E
name: Dryer, Frederick L.
name: Farouk, Tanvir I
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Astronomy, Astrophysics, Space Science
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology

description: The ‘FLame EXtinguishment’ (FLEX) program conducted by NASA on board the International Space Station (ISS) has been assisting in developing fire-safety protocols for low gravity applications through microgravity droplet combustion experiments. A wide range of fuels including alcohols and alkanes have been studied in different ambient conditions that also encompass the use of various diluent species and concentrations. A prime focus of the work has been to observe the relative effectiveness of atmospheric composition and pressure changes on fire suppression under ‘reduced’ gravity conditions. Here, detailed numerical simulations are performed to investigate the combustion and extinction characteristics of isolated sphero-symmetric 1.0-2.0 mm diameter methanol droplets burning in xenon (Xe) enriched environments. Comparisons of diluent behaviors under identical conditions using argon (Ar), carbon dioxide (CO2) and helium (He) as the alternative diluent to nitrogen are also reported. The predictions are compared against ISS experiments with good agreement and with less satisfactory agreement with the results published earlier by Shaw et al. (2012). Xenon as diluent rather than nitrogen results in reduced burning rate, larger extinction diameter and counter intuitively, prolonged burning time. The limiting oxygen index (LOI) for xenon is found to decrease significantly from that found with argon, carbon dioxide or helium. The numerical analyses indicate that the lower thermal diffusivity of xenon is the principal factor responsible for the remarkably lower LOI. Water accumulation within the methanol droplet and its relevance to the extinction process is also discussed. It is concluded that the combined observation of elevated peak gas temperature, its slow decay due to minimal diffusive heat loss and the exceptionally lower LOI value associated with xenon as a diluent all detract from its utility for suppressing fire concerns in reduced gravity applications.
A particle swarm optimization-based neural network for detecting nocturnal hypoglycemia using electroencephalography signals
Creators: name: Nguyen, Lien B.
name: Nguyen, Anh V.
name: Ling, Sai Ho
name: Nguyen, Hung
Publisher: name: Swinburne
Year: 2024

description: For patients with Type 1 Diabetes Mellitus (T1DM), hypoglycemia or the state of low blood glucose level is a very common but dangerous complication. Hypoglycemia episodes can lead to a large number of serious symptoms and effects, including unconsciousness, coma and even death. The variety of hypoglycemia symptoms is originated from the inadequate supply of glucose to the brain. By analyzing electroencephalography (EEG) signals from five T1DM patients during an overnight study, we find that under hypoglycemia, both centroid theta frequency and centroid alpha frequency change significantly against non-hypoglycemia conditions. Furthermore, a neural network is developed to detect hypoglycemia using the mentioned two EEG features. A standard particle swarm optimization strategy is applied to optimize the parameters of this neural network. By using the proposed method, we obtain the classification performance of 82% sensitivity and 63% specificity. The results demonstrate that hypoglycemia episodes can be detected non-invasively and effectively from EEG signals.
Fully human anti-BAFF inhibitory monoclonal antibody tabalumab does not adversely affect T-dependent antibody responses in cynomolgus monkey (Macaca fasicularis): A summary of three pre-clinical immunotoxicology evaluations
Creators: name: Komocsar, Wendy J.
name: Blackbourne, Jamie L.
name: Halstead, Carolyn A.
name: Winstead, Colleen J.
name: Wierda, Daniel
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Pharmacology
subject: Physiology
subject: Cell Biology
subject: Engineering

description: The potential immunotoxicity of tabalumab was assessed as a component of standard pre-clinical toxicology studies in cynomolgus monkeys. To evaluate potential tabalumab-associated immunosuppression after antigen challenge, cynomolgus monkeys were administered placebo control or tabalumab in three immunotoxicological safety studies. Study 1, a 4-week pilot study, evaluated biweekly intravenous (IV) control, and 0.3, 1.0, 5.0, and 15.0 mg/kg tabalumab doses. Study 2 evaluated IV control, and 0.1, 1.0, and 30.0 mg/kg tabalumab doses biweekly for 6 weeks. Study 3 evaluated IV control and 0.1, 1.0, 30.0 mg/kg, and subcutaneous (SC) 30.0 mg/kg tabalumab biweekly for 6 months, with recovery (16 weeks) to monitor standard immunotoxicity endpoints. T-cell dependent primary and secondary antibody responses to tetanus toxoid antigen challenge (4-week and 6-week studies) or keyhole limpet hemocyanin (KLH; 6-week and 6-month studies) were evaluated as a measure of immunocompetence, together with quantitation of T- and B-cell subsets. In addition, anti-tabalumab antibody formation (6-week and 6-month studies) was assessed. The results indicated that, despite expected decreases in circulating B-cell populations, no changes in follicle histopathology or organ weights, except decreases in spleen weight (after 6-months of 30 mg/kg IV/SC treatment only), were attributed to tabalumab. Non-adverse microscopic decreases in size or number of germinal centers in spleen, mesenteric, and mandibular lymph nodes occurred, but without an effect on antibody responses to KLH or tetanus. At 16-weeks recovery, microscopic compound-related changes observed after 6 months of treatment were completely reversed (0.1 mg/kg group) and partially reversed (1.0 and 30.0 mg/kg groups), while peripheral blood B cells remained 66–72% reduced from baseline. Despite reduced germinal centres in lymphoid organs, and reductions in circulating B cells, T-cell-dependent humoral immunity was maintained following tabalumab administration in three safety studies in cynomolgus monkeys.
Total leisure noise exposure and its association with hearing loss among adolescents
Creators: name: Steffens, Thomas
name: Bolte, Gabriele
name: Dehnert, Knut
name: Raab, Ulla
name: Perez-Alvarez, Carmelo
name: Fromme, Hermann
name: Twardella, Dorothee
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Neuroscience
subject: Molecular Biology

description: Objective: To investigate total leisure noise exposure among adolescents and to assess its association with hearing. Design: Based on self-reported time spent on 19 leisure activities and associated mean sound pressure levels reported in the literature, total leisure noise exposure was evaluated and compared to noise at work limits (> 85 dB(A) = hazardous) in a cross-sectional survey. Tympanometry and pure-tone audiometry was performed in sound isolated rooms. Study sample: The study sample consists of 2143 pupils attending grade nine in any school in a German city 2009–2011 (mean age: 15.4 years; range: 13–19 years). Audiometric data were available for 1837 (85.8%) pupils (53.9% girls). Results: 41.9% of the 2143 adolescents who had provided self-reported data on leisure activities associated with noise exposure were estimated to be hazardously exposed to leisure time noise. The interaction of gender with total leisure time noise exposure was not significant. No association between leisure time noise exposure and audiometric notches could be detected. Conclusion: While hearing loss seems seldom in this age group, a high proportion of adolescents aged 15–16 years are exposed to noise levels during leisure time bearing long-term risks of hearing loss.
Hyperpolarized magnetic resonance spectroscopy for assessing tumor hypoxia
Creators: name: Iversen, Ane B.
name: Ringgaard, Steffen
name: Laustsen, Christoffer
name: Stødkilde-Jørgensen, Hans
name: Bentzen, Lise
name: Busk, Morten
name: Horsman, Michael R.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cell Biology
subject: Medicine
subject: Engineering
subject: Biochemistry

description: ABSTRACTIntroduction. Hypoxic tumor cells are radioresistant, therefore, identification of hypoxia is crucial. Hyperpolarized magnetic resonance spectroscopy (HPMRS) allows real time measurements of the conversion of pyruvate to lactate, the final step of anaerobic energy production, and may thus allow non-invasive identification of hypoxia or treatment-induced changes in oxygenation. The aim of the study was to investigate the usefulness of HPMRS as a means to assess tumor hypoxia and its dynamics during intervention.Material and methods. C3H mammary carcinomas grown in CDF1 mice were used. To manipulate with tumor oxygenation, non-anaesthetized mice were gassed with air, 10% or 100% oxygen prior to administration of hyperpolarized [1-¹³C]pyruvate and HPMRS analysis. A direct assessment of tumor oxygen partial pressure (pO2) distributions were made using the Eppendorf oxygen electrode in a separate, but similarly treated, group of mice.Results. Even though breathing 100% oxygen improved tumor oxygenation as evidenced by pO2 measurements, the mean (with 1 S.E.) [1-¹³C]lactate/[1-¹³C]pyruvate ratio was unaffected by this intervention, being 34 (30–37) in mice breathing air and 37 (33–42) in mice breathing 100% oxygen. In contrast, and in accordance with pO2 measurements, a significant increase in the [1-¹³C]lactate/[1-¹³C]pyruvate ratio was seen in 10% oxygen-breathing mice with a ratio of 46 (42–50).Conclusions. Although, no metabolic change was observed during 100% O2 breathing using HPMRS, the significant increase in the [1-¹³C]lactate/[1-¹³C]pyruvate ratio during 10% oxygen breathing suggests, that HPMRS can detect hypoxia-driven changes in the metabolic fate of pyruvate. To what extent and for what purposes HPMRS may best supplement or complement established techniques like hypoxia PET needs to be unraveled in future research.
title: 01_0800
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: 01_1414
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Experimental observation of surface currents produced by WEC radiation and diffraction
Creators: name: Fleming, Alan
name: Manasseh, Richard
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 4017
subject: Mechanical engineering
subject: FOS: Mechanical engineering

description: The installation of Wave Energy Converters (WECs) in the environment inevitably makes an impact on the environment (whether positive or negative). One area of concern is the development of currents due to the interaction of the wave climate with the WEC and whether this might interfere with the pre-existing processes, such as sediment transport and currents. This paper reports on the observation of surface currents measured in experiments performed on a simple WEC analogue in different experimental conditions and finds that the surface currents are consistent with a pattern of toroidal vortices aligned with the axis along which the body oscillates.