cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
New Data from Shovakh Cave and Its Implications for Reconstructing Middle Paleolithic Settlement Patterns in the Amud Drainage, Israel
Creators: name: Friesem, David E.
name: Malinsky-Buller, Ariel
name: Ekshtain, Ravid
name: Gur-Arieh, Shira
name: Vaks, Anton
name: Mercier, Norbert
name: Richard, Maïlys
name: Guérin, Gilles
name: Valladas, Hélène
name: Auger, François
name: Hovers, Erella
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
Middle Palaeolithic
Site formation processes
Geoarchaeology
Levant
Amud drainage
Caves

description: Abstract: This study presents the geoarchaeological and geochronological aspects of Shovakh Cave and the first comparative context to the nearby Amud Cave (~ 500 m downstream), providing an exceptional opportunity to explore the range of human behaviours within a small geographic area. Sediment samples from two newly excavated areas at the rear and entrance of the cave were analysed using infrared spectroscopy, micromorphology and phytolith analysis and dated through uranium-thorium and luminescence techniques. The rear of the cave shows carnivore activity and low artefact concentrations. It also exhibits a shift in sedimentation from wind-blown deposits to colluviation of terra rossa. Direct dating of the deposits associated with the Middle Palaeolithic (MP) occupation at this area could not be obtained due to the breccia forming at the lower part of the excavation area. However, the later phases of the Middle Palaeolithic occupation at this area gave an age estimate of 45.5 ± 3.7 ka. At the entrance of the cave, there are relatively more residues associated with human use of fire. Post-depositional processes in this area include decalcification of the upper layer, cementation of the lower layer and phosphatisation due to guano decomposition, which indicates that this area was probably roofed. The ages obtained in this area range between 67.5 ± 5.5 to 56.2 ± 5.9 ka, overlapping with the occupation time of Amud cave. The evidence from Shovakh Cave presents lower intensity of occupation compared to Amud, indicating variable modes of site use by humans in the Amud drainage during the Late Middle Palaeolithic.
Additional file 18 of Key factors for differential drought tolerance in two contrasting wild materials of Artemisia wellbyi identified using comparative transcriptomics
Creators: name: Liu, Huan
name: Wang, Qiyu
name: Wang, Jinglong
name: Liu, Yunfei
name: Renzeng, Wangdui
name: Zhao, Guiqin
name: Niu, Kuiju
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 18: Table S18. SRA accession numbers.
The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
Creators: name: Patton, Andrew P.
name: Edwards, Mathew D.
name: Smyllie, Nicola J.
name: Hamnett, Ryan
name: Chesham, Johanna E.
name: Brancaccio, Marco
name: Maywood, Elizabeth S.
name: Hastings, Michael H.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/378
/631/378/1385
/631/378/1385/1330
/14
/14/63
/42
/42/109
/64
/64/110
article

description: Abstract: The hypothalamic suprachiasmatic nuclei (SCN) are the principal mammalian circadian timekeeper, co-ordinating organism-wide daily and seasonal rhythms. To achieve this, cell-autonomous circadian timing by the ~20,000 SCN cells is welded into a tight circuit-wide ensemble oscillation. This creates essential, network-level emergent properties of precise, high-amplitude oscillation with tightly defined ensemble period and phase. Although synchronised, regional cell groups exhibit differentially phased activity, creating stereotypical spatiotemporal circadian waves of cellular activation across the circuit. The cellular circuit pacemaking components that generate these critical emergent properties are unknown. Using intersectional genetics and real-time imaging, we show that SCN cells expressing vasoactive intestinal polypeptide (VIP) or its cognate receptor, VPAC2, are neurochemically and electrophysiologically distinct, but together they control de novo rhythmicity, setting ensemble period and phase with circuit-level spatiotemporal complexity. The VIP/VPAC2 cellular axis is therefore a neurochemically and topologically specific pacemaker hub that determines the emergent properties of the SCN timekeeper.
VI3: a 2D Ising ferromagnet
Creators: name: Yang, Ke
name: Fan, Fengren
name: Wang, Hongbo
name: Khomskii, D. I.
name: Wu, Hua
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Two-dimensional (2D) magnetic materials are of great current interest for their promising applications in spintronics. Here we propose the van der Waals (vdW) material VI3 to be a 2D Ising ferromagnet (FM), using density functional calculations, crystal field level diagrams, superexchange model analyses, and Monte Carlo simulations. The $a_{1g}$$^1$$e'_{-}$$^1$ ground state in the trigonal crystal field gives rise to the 2D Ising FM due to a significant single ion anisotropy (SIA) and enhanced FM superexchange both associated with the $S_z$=1 and $L_z$=--1 state of V3+ ions. We find that a tensile strain on the VI3 monolayer further stabilizes the $a_{1g}$$^1$$e'_{-}$$^1$ ground state, and its Curie temperature ($T_{\rm C}$) would increase from 70 K to 90-110 K under a 2.5-5\% tensile strain. Moreover, we suggest a group of spin-orbital states with a strong SIA which may help to search more 2D Ising magnets.
description: 7 pages, 8 figures, 2 tables, Phys. Rev. B Rapid, in press
Mitochondrial DNA: the overlooked oncogenome?
Creators: name: Gammage, Payam A.
name: Frezza, Christian
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Review
Cancer Metabolism
BMC Biology Reviews
Mitochondria
mtDNA
Cancer
Metabolism

description: Abstract: Perturbed mitochondrial bioenergetics constitute a core pillar of cancer-associated metabolic dysfunction. While mitochondrial dysfunction in cancer may result from myriad biochemical causes, a historically neglected source is that of the mitochondrial genome. Recent large-scale sequencing efforts and clinical studies have highlighted the prevalence of mutations in mitochondrial DNA (mtDNA) in human tumours and their potential roles in cancer progression. In this review we discuss the biology of the mitochondrial genome, sources of mtDNA mutations, and experimental evidence of a role for mtDNA mutations in cancer. We also propose a ‘metabolic licensing’ model for mtDNA mutation-derived dysfunction in cancer initiation and progression.
Nepanamixis vectoris Thomas 1997
Creators: name: White, Kristine N.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Leucothoidae
Nepanamixis
Nepanamixis vectoris

description: Nepanamixis vectoris Thomas, 1997
 Nepanamixis vectoris Thomas, 1997: 79–81, fig. 22.
 Type locality and specimens. Pinas Bay, Panama. Holotype, anamorph male, 2.69 mm, USNM 131571.
 Material examined. No material available for examination. Diagnosis based on description by Thomas (1997).
 Diagnosis. Gnathopod 1 carpus with large apical spine; propodus with distal process. Gnathopod 2 carpus with elevated serrate lateral ridge.
 Leucomorph (juvenile/sexually dimorphic characters). Unknown.
 Habitat. Among coral; 4–7 m.
 Host. Unknown.
 Distribution. Pacific Ocean: Panama (Thomas 1997).
description: Published as part of White, Kristine N., 2011, A taxonomic review of the Leucothoidae (Crustacea: Amphipoda) 3078, pp. 1-113 in Zootaxa 3078 (1) on page 25, DOI: 10.11646/zootaxa.3078.1.1, http://zenodo.org/record/5243821
Features of an Experimental Station at an International Agricultural Research Center that Enhance Regional Impact
Creators: name: John, Ryan
name: Colin, Norwood
name: Juergen, Diekmann
name: John, Ryan
name: Colin, Norwood
name: Juergen, Diekmann
Publisher: name: Unknown
Year: 2012
Subjects: Agricultural and Food Policy
Agricultural Finance

description: Adequately equipped field stations are essential for any institution involved with applied agricultural research. The field station is particularly crucial to the functioning of the network of global international research centers. The International Center for Agricultural Research in the Dry Areas addresses issues mainly related to dryland cropping system of the West Asia and North Africa region. It extends its effectiveness in northern Syria through a range of sub-stations and on-farm sites across the rainfall transect (150-600 mm). This article describes the environment and management of the Center that backstops its applied and adaptive research. Particular strengths of the station are highlighted. Unique features of the station that further the technology generation and transfer are described. While some aspects of international research station management are generic, there are considerations described that are specific to an evolving dryland research center in a rapidly changing region.
A hybrid algorithm framework for small quantum computers with application to finding Hamiltonian cycles
Creators: name: Ge, Yimin
name: Dunjko, Vedran
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Computational Complexity (cs.CC)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Recent works have shown that quantum computers can polynomially speed up certain SAT-solving algorithms even when the number of available qubits is significantly smaller than the number of variables. Here we generalise this approach. We present a framework for hybrid quantum-classical algorithms which utilise quantum computers significantly smaller than the problem size. Given an arbitrarily small ratio of the quantum computer to the instance size, we achieve polynomial speedups for classical divide-and-conquer algorithms, provided that certain criteria on the time- and space-efficiency are met. We demonstrate how this approach can be used to enhance Eppstein's algorithm for the cubic Hamiltonian cycle problem, and achieve a polynomial speedup for any ratio of the number of qubits to the size of the graph.
description: 20+2 pages
Quantum Corrections to Q-Balls
Creators: name: Graham, N.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We extend calculational techniques for static solitons to the case of field configurations with simple time dependence in order to consider quantum effects on the stability of Q-balls. These nontopological solitons exist classically for any fixed value of an unbroken global charge Q. We show that one-loop quantum effects can destabilize very small Q-balls. We show how the properties of the soliton are reflected in the associated scattering problem, and find that a good approximation to the full one-loop quantum energy of a Q-ball is given by $ω- E_0$, where $ω$ is the frequency of the classical soliton's time dependence, and $E_0$ is the energy of the lowest bound state in the associated scattering problem.
description: 6 pages, 2 figures, uses RevTex4; v2: replaced figures
M-41933 corrections definitives.pdf
Creators: name: EL HASSANE Dit PAUL HASSANA SIDIBE
Publisher: name: figshare
Year: 2019
Subjects: subject: 60104 Cell Metabolism
subject: FOS: Biological sciences

description: UNIVERSITE DE DAKAR  FACULTE DE MEDECINE ET DE PHARMACIE
 ANNEE 1984 N°31 L’HYPOTHYROIDIE PRIMAIRE AU SENEGAL (à propos de 24 observations chez l’adulte) THESE d’ANTHROPOLOGIE MEDICALE PRESENTEE ET SOUTENUE PUBLIQUEMENT LE 28 MARS 1984 pour obtenir le grade de Docteur Phil. en Médecine (Diplôme D’ETAT) Par EL Hassane SIDIBE Né le 12 mai 1951 A Thilène (Saint-Louis du Senegal) Ancien Interne des Hôpitaux de Dakar en clinique Médicale-Médecine Interne Président de Jury : Professeur Herve de LAUTURE Directeur de Thèse : Professeur Ahmédou Moustapha SOW
title: Lysophosphatidylcholine acyltransferase-2 (LPCAT-2) & protein S-acylation in macrophage innate immunity
Creators: name: Good, Christian Robin
Publisher: name: University of Plymouth
Year: 2024
Subjects: subject: Macrophage
subject: Protein acylation
subject: Lysophosphatidylcholine acyltransferase-2
subject: Innate immunity
subject: PhD

description: Lysophosphatidylcholine acyltransferase (LPCAT)2 is an enzyme involved in remodelling glycerophospholipids within cell membranes and the generation of platelet-activating factor. LPCAT2 also mediates lipopolysaccharide (LPS)-induced cytokine responses in both murine and human macrophages. Investigations into the mechanism behind LPCAT2 involvement into LPS-induced cytokine responses identified that LPCAT2 translocates to membrane lipid raft domains and associates with toll-like receptor (TLR)4 following activation by LPS. The mechanism behind this is not known, however LPCAT2 appears to have a role in regulating innate immune responses via lipid raft signalling complexes and understanding the molecular details of these mechanisms could help in the development of targeted anti-inflammatory therapies. The aim of this thesis is to build on these findings to develop a detailed molecular analysis of the mechanisms by which LPCAT2 can regulate inflammatory responses in macrophages. It has been reported that LPCAT1 can catalyse the acylation of histone proteins. The addition of lipid groups to a protein can impact membrane-protein association, protein structure and protein stability ultimately affecting a proteins function. This gave rise to the main research question explored in this thesis: Does LPCAT2 play a role in the S-acylation of proteins involved in LPS signalling? To identify if LPCAT2 plays a role in protein S-acylation in LPS stimulated macrophages, siRNAs were used to knockdown the protein expression of LPCAT2 in LPS stimulated RAW264.7 cells combined with acyl-biotin exchange chemistry, a method of purifying S-acylated proteins. The purified proteins could then be identified by tandem mass spectrometry and western blotting. Changes in the level of protein S-acylation could then be compared between cells expressing normal levels of LPCAT2 and cells expressing reduced levels of LPCAT2. This thesis identified for the first time a link between LPCAT2 and protein S-acylation in LPS stimulated macrophages. Western blot analysis confirmed the acylation of the scavenger receptors CD36 and Lysosome membrane protein II. Further investigation established that CD36 positively regulates LPS induced cytokine responses in macrophages and that S-acylation of CD36 regulates both lipid raft association and surface expression. This highlights a mechanism in which LPCAT2 mediates the S-acylation of CD36 which is required for surface and lipid raft association where CD36 most likely influences LPS signalling. These findings are not only relevant to inflammatory conditions that are mediated by LPS and TLR4 signalling but could also have implications for various inflammatory diseases such as Atherosclerosis and Alzheimer’s disease in which CD36 plays a major role in their pathology.
Mr-moslo: vm consolidation using multiple regression multi-objective seven-spot ladybird optimization for host overload detection
Creators: name: Alhammadi, Akram Saeed Aqlan
name: Vasanthi, Dr. V.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Virtual Machine (VM)consolidation is a crucial process in improving the utilization of the resource in cloud computing services.As the cloud data centers consume high electrical power,the operational costs and carbon dioxide releases increases.The inefficient usage of the resources is the main reason for these problems and VM consolidation is a viable solution.VM consolidation includes host overload/under-load detection,VM selection and VM placement processes.Most existing host overload/under-load detection approaches of VM consolidation uses CPU utilization only for the determining host load.In this paper,three resources namely CPU utilization,memory utilization and bandwidth utilization are used for host overload detection and an adaptive regression based model called Multiple Regression Multi-Objective Seven-Spot Ladybird Optimization(MR-MOSLO) is proposed.This model is based on combining the benefits of adaptive threshold based and regression based host overload detection algorithms.This approach of combining these features provide more advantages for threshold setting in dynamic environments with accurate prediction of host overloading.For this purpose, initially,Multiple Regression (MR)algorithm is used which relay on CPU utilization,memory utilization and bandwidth utilization for estimation of the host load conditions.Then a Multi-Objective Seven-Spot Ladybird Optimization(MOSLO)algorithm is introduced to select the upper and lower threshold limits for host utilization.Based on these algorithms,the host overload/under-load is detected with high accuracy and less power consumption.The simulations are conducted in CloudSim tool and the empirical results shows that the proposed MR-MOSLO algorithm detects the host overload efficiently with reasonably similar energy and SLA values while comparatively lesser SLATAH,PDM,SLAV and ESV values than most of the existing methods.
J/psi production in relativistic heavy ion collisions from a multi-phase transport model
Creators: name: Zhang, Bin
name: Ko, C. M.
name: Li, Bao-An
name: Lin, Zi-Wei
name: Pal, Subrata
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Using A Multi-Phase Transport (AMPT) model, we study J/psi production from interactions between charm and anti-charm quarks in initial parton phase and between D and Dbar mesons in final hadron phase of relativistic heavy ion collisions at the Relativistic Heavy Ion Collider (RHIC). Including also the inverse reactions of J/psi absorption by gluons and light mesons, we find that the net number of J/psi from the parton and hadron phases is smaller than that expected from the superposition of initial nucleon-nucleon collisions, contrary to the J/psi enhancement predicted by the kinetic formation model. The production of J/psi is further suppressed if one includes the color screening effect in the parton phase. We have also studied the dependence of J/psi production on the charm quark mass and the effective charm meson mass.
description: Figures redone with better statistics
Additional file 2 of Validity and reliability of the Amharic version of supportive care needs survey - short form 34 among cancer patients in Ethiopia
Creators: name: Tsion Afework
name: Abigiya Wondimagegnehu
name: Natnael Alemayehu
name: Kantelhardt, Eva Johanna
name: Adamu Addissie
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2: Table 2. Standardized Regression Weight for SCNS Tool in Hawassa comprehensive specialized Hospital, SNNPR, Ethiopia, 2019. This is output from AMOS; it shows how each of the observed variables loads on each construct. Each load more than 0.5.
Development and characterization of a “store and create” microfluidic device to determine the heterogeneous freezing properties of ice nucleating particles
Creators: name: Brubaker, Thomas
name: Polen, Michael
name: Cheng, Perry
name: Ekambaram, Vinay
name: Somers, Josh
name: Anna, Shelley L.
name: Sullivan, Ryan C.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: Inorganic Chemistry

description: Understanding heterogeneous ice nucleation induced by ice nucleating particles (INPs) is hindered by analytical challenges in accurately determining the freezing temperature spectrum, abundance, and physicochemical properties of INPs. Here we evaluate the performance of a microfluidic device that employs a “store and create” approach to measure the ice nucleation properties of approximately 600 uniformly sized nanoliter water droplets. These droplets are immersed in surfactant-free environmentally sustainable squalene oil and do not contact the polymer walls of the microfluidic device. The device interfaced with a cold plate temperature controller has a greatly reduced background freezing temperature spectrum for filtered water droplets compared to conventional microliter droplet-on-substrate freezing methods. Droplets containing particles of interest are readily generated on-chip from a suspension of particles in water. Background freezing for 6 nL water droplets exhibits a median freezing temperature of −33.7 ± 0.4 °C, close to the theoretical freezing temperature of −34.5 °C. The immersion freezing temperature spectra obtained from Snomax bacterial and illite mineral particles compares well with literature data, and the freezing contribution from either type of particle can be separated from a mixed suspension. Our approach generates a highly uniform droplet size distribution, causes no clogging of the microfluidic device, and is capable of reproducible droplet refreezes. The high-resolution freezing spectra obtained from large droplet number arrays enables the use of the derivative INP temperature spectrum analysis to quantitatively distinguish between different classes of INPs. The lower and consistent filtered water background freezing temperature enables measurements of almost the entire immersion freezing temperature regime from −33 to 0 °C, and quantification of weaker but often abundant INPs such as those found in biomass-burning smoke aerosol. Copyright © 2019 American Association for Aerosol Research
“Fear of Physics” by Lawrence M. Krauss
Creators: name: Antão, Manuel
Publisher: name: figshare
Year: 2019
Subjects: General Relativity
Special Relativity

description: “And why does the Higgs exist, if it does? Is there a more fundamental theory that explains its existence, along with that of electrons, quarks, photos, and W and Z particles?”
In “Fear of Physics” by Lawrence M. Krauss

“Electricity and magnetism are the different ‘shadows’ of a single force, electromagnetism, as viewed from different vantage points, which depend upon your relative state of motion.”
In “Fear of Physics” by Lawrence M. Krauss

“We appear, with reasonably high precision, to live in a flat universe.” (*)
In “Fear of Physics” by Lawrence M. Krauss

NB: (*) This book was published in 2006. In 2019, my take on this is quite different.
Socio-economic Impacts on Human Life in Arsenic Affected Area of Basti Rasul Pur, Rahim Yar Khan, Pakistan
Creators: name: Islam Ul Haq, Lt Col
name: Hanif, Waqas
name: Hasnain, Ghalib
name: Durez, Shahid
name: Islam Ul Haq, Lt Col
name: Hanif, Waqas
name: Hasnain, Ghalib
name: Durez, Shahid
Publisher: name: Unknown
Year: 2012
Subjects: Agricultural and Food Policy
Agricultural Finance

description: The availability and scarcity of both surface and ground water alongwith adverse impacts of contaminated water have become major problems in Pakistan. Groundwater arsenic contamination in the southern part of the country has exponentially endangered the human life and complicated the efforts to provide safe drinking water in the arsenic contaminated areas. To gauge the adverse impacts amongst the affected population, household survey in Basti Rasul Pur district Rahim Yar Khan was conducted on core socio-economic indicators such as household conditions, sex ratio, earning sources, literacy, health morbidity, water borne diseases, drinking water contamination, education, employment and unemployment, expenditure on hospitalization for drawing best possible conclusions. Resultantly, sex ratio observed was about 1.01% for adults and 9.8 % for children. A total of 77 % water samples were found with arsenic contamination, due to which 50 % people were found with arsencosis symptoms and 60% of their earnings were being spent on hospitalization. Due to poverty and illiteracy, the entire population was un-aware of the adverse impacts of drinking water arsenic contamination. There is a dire need of installation of sustainable community based arsenic mitigation technologies for provisioning of safe drinking water to affected community.
Paranamixis Schellenberg 1938
Creators: name: White, Kristine N.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Leucothoidae
Paranamixis

description: Paranamixis Schellenberg, 1938
 Paranamixis Schellenberg, 1938a: 29.
 Type-species. Paranamixis bocki Schellenberg, 1938a, monotypy.
 Diagnosis. (Terminal males) Antennae relatively long. Eyes with 10 or more ocelli. Maxilliped inner plates generally fused or vestigial; outer plates lacking inner lobes. Coxa 1 greatly reduced, remainder of gnathopod 1 absent, occasionally a small vestige in transformational males.
 Relationships. Differing from Leucothoe and Paraleucothoe in the reduced mouthparts, reduced coxa 1, and extreme sexual dimorphism. Differing from Anamixis in the often vestigial maxilliped inner plates and the absence of gnathopod 1 in post-transformational molts. Differing from Nepanamixis in the relatively longer antennae, more numerous ocelli, smaller coxa 1, smaller gnathopod 1 carpus, gnathopod 2 with one mediofacial setal row, and shorter telson.
 Species. Paranamixis aberro Hirayama, 1983; Paranamixis bocki Schellenberg, 1938a; Paranamixis clarkae Thomas, 1997; Paranamixis denticulus Kim & Kim, 1991b; Paranamixis excavatus Ledoyer, 1978a; Paranamixis fijiensis Thomas, 1997; Paranamixis indicus Sivaprakasam, 1968; Paranamixis jiigurru White & Thomas, 2009; Paranamixis kanu Thomas, 1997; Paranamixis ledoyeri Ortiz & Lalana, 1997; Paranamixis madagascarensis Ledoyer, 1982; Paranamixis misakiensis Thomas, 1997.
 Other records. Paranamixis sp. (P. madagascarensis) Myers, 1986: 272; Paranamixis sp. A Jansen & Dinesen, 2002: 267, fig. 1a–b; Paranamixis sp. B Jansen & Dinesen, 2002: 267, 268, fig. 1c.
 Habitat and distribution. Marine, Indo–Pacific, Red Sea, East China Sea, South China Sea, Sea of Japan, Andaman Sea, South Pacific, North Pacific, Indian Ocean, 0–30 m, in sponges, ascidians, algae, seagrasses, coral rubble and among live corals, 13 species.
description: Published as part of White, Kristine N., 2011, A taxonomic review of the Leucothoidae (Crustacea: Amphipoda) 3078, pp. 1-113 in Zootaxa 3078 (1) on pages 25-26, DOI: 10.11646/zootaxa.3078.1.1, http://zenodo.org/record/5243821
Factor Analysis of Paddy-Field Consolidation: Case Study of Iran
Creators: name: Sadegh, Ebrahimi Mohammad
name: Khalil, Kalantri
name: Ali, Asadi
name: Sadegh, Ebrahimi Mohammad
name: Khalil, Kalantri
name: Ali, Asadi
Publisher: name: Unknown
Year: 2012
Subjects: Agricultural and Food Policy
Agricultural Finance

description: Land consolidation is a strategy for the development of Iranian rice-growing regions. The most important targets of the program are reducing rice farmers' expenses and increasing their income. The object of this article is to conduct a factor analysis of Iranian paddy-field consolidation. The research was conducted in the form of a survey study. The data was collected from188 farmers participating in a farm-development program in Guilan province, sampled using a stratified random sampling method. The reliability of the questionnaire was calculated using a Cronbach alpha coefficient (alpha >0.78) for different sections after conducting a pilot study. Factor analysis for farmers with rice fields in projects showed that five factors explained 63.92% of total variance. These factors were: 1) social, 2) instructional, 3) environmental, 4) economic and 5) institutional effects. Social effects alone, the factor with the greatest effect, explained 34.84% of total variance.
A user guide for the online exploration and visualization of PCAWG data
Creators: name: Goldman, Mary J.
name: Zhang, Junjun
name: Fonseca, Nuno A.
name: Cortés-Ciriano, Isidro
name: Xiang, Qian
name: Craft, Brian
name: Piñeiro-Yáñez, Elena
name: O’Connor, Brian D.
name: Bazant, Wojciech
name: Barrera, Elisabet
name: Muñoz-Pomer, Alfonso
name: Petryszak, Robert
name: Füllgrabe, Anja
name: Al-Shahrour, Fatima
name: Keays, Maria
name: Haussler, David
name: Weinstein, John N.
name: Huber, Wolfgang
name: Valencia, Alfonso
name: Park, Peter J.
name: Papatheodorou, Irene
name: Zhu, Jingchun
name: Ferretti, Vincent
name: Vazquez, Miguel
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/61/212
/631/67/69
/631/208/69
/139
article

description: Funder: U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI)
description: Funder: Ontario Institute for Cancer Research (Institut Ontarien de Recherche sur le Cancer); doi: https://doi.org/10.13039/100012118
description: Funder: EMBL Member States EU FP7 Programme projects EurocanPlatform (260791) CAGEKID (241669)
description: Funder: European Union’s Framework Programme For Research and Innovation Horizon 2020 under the Marie Sklodowska-Curie grant agreement no. 703543
description: Funder: Michael & Susan Dell Foundation; Mary K. Chapman Foundation; CCSG Grant P30 CA016672 (Bioinformatics Shared Resource); ITCR U24 CA199461; GDAN U24 CA210949; GDAN U24 CA210950
description: Funder: European Commission's H2020 Programme, project SOUND, Grant Agreement no 633974
description: Funder: Spanish Government (SEV 2015-0493) BSC-Lenovo Master Collaboration Agreement (2015)
description: Abstract: The Pan-Cancer Analysis of Whole Genomes (PCAWG) project generated a vast amount of whole-genome cancer sequencing resource data. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we provide a user’s guide to the five publicly available online data exploration and visualization tools introduced in the PCAWG marker paper. These tools are ICGC Data Portal, UCSC Xena, Chromothripsis Explorer, Expression Atlas, and PCAWG-Scout. We detail use cases and analyses for each tool, show how they incorporate outside resources from the larger genomics ecosystem, and demonstrate how the tools can be used together to understand the biology of cancers more deeply. Together, the tools enable researchers to query the complex genomic PCAWG data dynamically and integrate external information, enabling and enhancing interpretation.
ESM-FIG4.pdf from Enhanced heterogenous hydration of SO2 through immobilization of pyridinic-N on carbon materials
Creators: name: Zou, Longhua
name: Yan, Ping
name: Lu, Peng
name: Chen, Dongyao
name: Chu, Wei
name: Cen, Wanglai
Publisher: name: The Royal Society
Year: 2020

description: Carbon materials doped with nitrogen have long been used for SO2 removal from flue gases for the benefits of the environment. The role of water is generally regarded as hydration of SO3 which is formed through the oxidization of SO2. However, the hydration of SO2, especially on the surface of N doped carbon materials, was almost ignored. In this study, the hydration of SO2 was investigated in detail on the pyridinic nitrogen (PyN) doped graphene (GP) surfaces. It is found that, compared to the homogeneous hydration of SO2 assisted with NH3 in gas phase, the heterogeneous hydration is much more thermodynamically and kinetically favourable. Specifically, when a single H2O molecule is involved, the energy barrier for SO2 hydration is as low as 0.15 eV, with 0.59 eV released, indicating the hydration of SO2 can occur at rather low water concentration and temperature. Thermodynamic integration molecular dynamics results show the feasibility of the hydrogenated substrate recovery and the immobilized N acting as a catalytic site for SO2 hydration. Our findings show that the heterogeneous hydration of SO2 should be universal and potentially uncover the puzzling reaction mechanism for SO2 catalytic oxidation at low temperature by N doped carbon materials.
Anisotropic Proton and Oxygen Ion Conductivity in Epitaxial Ba2In2O5 Thin Films
Creators: name: Fluri, Aline
name: Karlsson, Maths
name: Bettinelli, Marco
name: Castelli, Ivano E.
name: Lippert, Thomas
name: Pergolesi, Daniele
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Solid oxide oxygen ion and proton conductors are a highly important class of materials for renewable energy conversion devices like solid oxide fuel cells. Ba2In2O5 (BIO) exhibits both oxygen ion and proton conduction, in dry and humid environment, respectively. In dry environment, the brownmillerite crystal structure of BIO exhibits an ordered oxygen ion sublattice, which has been speculated to result in anisotropic oxygen ion conduction. The hydrated structure of BIO, however, resembles a perovskite and the protons in it were predicted to be ordered in layers. To complement the significant theoretical and experimental efforts recently reported on the potentially anisotropic conductive properties in BIO, we measure here the proton and oxygen ion conductivity along different crystallographic directions. Using epitaxial thin films with different crystallographic orientations the charge transport for both charge carriers is shown to be anisotropic. The anisotropy of the oxygen ion conduction can indeed be explained through the layered structure of the oxygen sublattice in brownmillerite BIO. The anisotropic proton conduction however, further supports the suggested ordering of the protonic defects in the material. The differences in proton conduction along different crystallographic directions attributed to proton ordering in BIO are of a similar extent as those observed along different crystallographic directions in materials where proton ordering is not present but where protons find preferential conduction pathways through chain-like or layered structures.
QSAR-derived affinity fingerprints (part 2): modeling performance for potency prediction
Creators: name: Cortés-Ciriano, Isidro
name: Škuta, Ctibor
name: Bender, Andreas
name: Svozil, Daniel
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research Article
Big Data in Chemistry
QSAR
Affinity fingerprints
ChEMBL
Bioactivity modeling
Cytotoxicity
Drug sensitivity prediction
Drug sensitivity

description: Abstract: Affinity fingerprints report the activity of small molecules across a set of assays, and thus permit to gather information about the bioactivities of structurally dissimilar compounds, where models based on chemical structure alone are often limited, and model complex biological endpoints, such as human toxicity and in vitro cancer cell line sensitivity. Here, we propose to model in vitro compound activity using computationally predicted bioactivity profiles as compound descriptors. To this aim, we apply and validate a framework for the calculation of QSAR-derived affinity fingerprints (QAFFP) using a set of 1360 QSAR models generated using Ki, Kd, IC50 and EC50 data from ChEMBL database. QAFFP thus represent a method to encode and relate compounds on the basis of their similarity in bioactivity space. To benchmark the predictive power of QAFFP we assembled IC50 data from ChEMBL database for 18 diverse cancer cell lines widely used in preclinical drug discovery, and 25 diverse protein target data sets. This study complements part 1 where the performance of QAFFP in similarity searching, scaffold hopping, and bioactivity classification is evaluated. Despite being inherently noisy, we show that using QAFFP as descriptors leads to errors in prediction on the test set in the ~ 0.65–0.95 pIC50 units range, which are comparable to the estimated uncertainty of bioactivity data in ChEMBL (0.76–1.00 pIC50 units). We find that the predictive power of QAFFP is slightly worse than that of Morgan2 fingerprints and 1D and 2D physicochemical descriptors, with an effect size in the 0.02–0.08 pIC50 units range. Including QSAR models with low predictive power in the generation of QAFFP does not lead to improved predictive power. Given that the QSAR models we used to compute the QAFFP were selected on the basis of data availability alone, we anticipate better modeling results for QAFFP generated using more diverse and biologically meaningful targets. Data sets and Python code are publicly available at https://github.com/isidroc/QAFFP_regression.
The onset of thermo-compositional convection in rotating spherical shells
Creators: name: Silva, Luis
name: Mather, James F.
name: Simitev, Radostin D.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: Double-diffusive convection driven by both thermal and compositional buoyancy in a rotating spherical shell can exhibit a rather large number of behaviours often distinct from that of the single diffusive system. In order to understand how the differences in thermal and compositional molecular diffusivities determine the dynamics of thermo-compositional convection we investigate numerically the linear onset of convective instability in a double-diffusive setup. We construct an alternative equivalent formulation of the non-dimensional equations where the linearised double-diffusive problem is described by an effective Rayleigh number, $\text{Ra}$, measuring the amplitude of the combined buoyancy driving, and a second parameter, $α$, measuring the mixing of the thermal and compositional contributions. This formulation is useful in that it allows for the analysis of several limiting cases and reveals dynamical similarities in the parameters space which are not obvious otherwise. We analyse the structure of the critical curves in this $\text{Ra}-α$ space, explaining asymptotic behaviours in $α$, transitions between inertial and diffusive regimes, and transitions between large scale (fast drift) and small scale (slow drift) convection. We perform this analysis for a variety of diffusivities, rotation rates and shell aspect ratios showing where and when new modes of convection take place.
description: Accepted for publication in Geophys. Astrophys. Fluid Dyn. on 2019-06-28 (Fist submitted on 2018-07-11). 24 pages, 10 figures
Additional file 4 of Validity and reliability of the Amharic version of supportive care needs survey - short form 34 among cancer patients in Ethiopia
Creators: name: Tsion Afework
name: Abigiya Wondimagegnehu
name: Natnael Alemayehu
name: Kantelhardt, Eva Johanna
name: Adamu Addissie
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 4: Table 4. Reliability of the scale of SCNS-26 tool in Hawassa comprehensive Specialized Hospital, Hawassa, Ethiopia, 2019. Reliability was checked for only the remaining 26 items, which the result shows, all the construct had good reliability, which yields the same result on repeated measurements.
Additional file 1 of The long pentraxin PTX3: a novel serum marker to improve the prediction of osteoporosis and osteoarthritis bone-related phenotypes
Creators: name: Visconti, Virginia Veronica
name: Greggi, Chiara
name: Fittipaldi, Simona
name: Casamassima, Donato
name: Mariagrazia Tallarico
name: Romano, Francesco
name: Botta, Annalisa
name: Tarantino, Umberto
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Table S1. Comorbidities and Medical treatments for OP, OA and CTR subjects.
Additional file 3 of Validity and reliability of the Amharic version of supportive care needs survey - short form 34 among cancer patients in Ethiopia
Creators: name: Tsion Afework
name: Abigiya Wondimagegnehu
name: Natnael Alemayehu
name: Kantelhardt, Eva Johanna
name: Adamu Addissie
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3: Table 3. Correlation between latent factors in Hawassa comprehensive Specialized Hospital, Hawwasa, Ethiopia, 2019. This shows if whether the five latent factors correlate with each other or not, which shows there is a high similarity in the items if there is a higher correlation.
Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries
Creators: name: Warren, Philippa M.
name: Andrews, Melissa R.
name: Smith, Marc
name: Bartus, Katalin
name: Bradbury, Elizabeth J.
name: Verhaagen, Joost
name: Fawcett, James W.
name: Kwok, Jessica C. F.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/80/84/750
/631/378/87
/631/378/1687/1825
article

description: Abstract: Schwann cell grafts support axonal growth following spinal cord injury, but a boundary forms between the implanted cells and host astrocytes. Axons are reluctant to exit the graft tissue in large part due to the surrounding inhibitory environment containing chondroitin sulphate proteoglycans (CSPGs). We use a lentiviral chondroitinase ABC, capable of being secreted from mammalian cells (mChABC), to examine the repercussions of CSPG digestion upon Schwann cell behaviour in vitro. We show that mChABC transduced Schwann cells robustly secrete substantial quantities of the enzyme causing large-scale CSPG digestion, facilitating the migration and adhesion of Schwann cells on inhibitory aggrecan and astrocytic substrates. Importantly, we show that secretion of the engineered enzyme can aid the intermingling of cells at the Schwann cell-astrocyte boundary, enabling growth of neurites over the putative graft/host interface. These data were echoed in vivo. This study demonstrates the profound effect of the enzyme on cellular motility, growth and migration. This provides a cellular mechanism for mChABC induced functional and behavioural recovery shown in in vivo studies. Importantly, we provide in vitro evidence that mChABC gene therapy is equally or more effective at producing these effects as a one-time application of commercially available ChABC.
Additional file 6 of Artificial intelligence-based refractive error prediction and EVO-implantable collamer lens power calculation for myopia correction
Creators: name: Jiang, Yinjie
name: Shen, Yang
name: Chen, Xun
name: Niu, Lingling
name: Li, Boliang
name: Cheng, Mingrui
name: Lei, Yadi
name: Xu, Yilin
name: Wang, Chongyang
name: Zhou, Xingtao
name: Wang, Xiaoying
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 6. Prediction performance in different ranges of axial length.
Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies
Creators: name: Schumacher, Julia
name: Taylor, John-Paul
name: Hamilton, Calum A.
name: Firbank, Michael
name: Cromarty, Ruth A.
name: Donaghy, Paul C.
name: Roberts, Gemma
name: Allan, Louise
name: Lloyd, Jim
name: Durcan, Rory
name: Barnett, Nicola
name: O’Brien, John T.
name: Thomas, Alan J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research
Dementia with Lewy bodies
Alzheimer’s disease
Quantitative electroencephalography
Biomarker

description: Funder: GE Healthcare; doi: http://dx.doi.org/10.13039/100006775
description: Abstract: Objectives: To investigate using quantitative EEG the (1) differences between patients with mild cognitive impairment with Lewy bodies (MCI-LB) and MCI with Alzheimer’s disease (MCI-AD) and (2) its utility as a potential biomarker for early differential diagnosis. Methods: We analyzed eyes-closed, resting-state, high-density EEG data from highly phenotyped participants (39 MCI-LB, 36 MCI-AD, and 31 healthy controls). EEG measures included spectral power in different frequency bands (delta, theta, pre-alpha, alpha, and beta), theta/alpha ratio, dominant frequency, and dominant frequency variability. Receiver operating characteristic (ROC) analyses were performed to assess diagnostic accuracy. Results: There was a shift in power from beta and alpha frequency bands towards slower frequencies in the pre-alpha and theta range in MCI-LB compared to healthy controls. Additionally, the dominant frequency was slower in MCI-LB compared to controls. We found significantly increased pre-alpha power, decreased beta power, and slower dominant frequency in MCI-LB compared to MCI-AD. EEG abnormalities were more apparent in MCI-LB cases with more diagnostic features. There were no significant differences between MCI-AD and controls. In the ROC analysis to distinguish MCI-LB from MCI-AD, beta power and dominant frequency showed the highest area under the curve values of 0.71 and 0.70, respectively. While specificity was high for some measures (up to 0.97 for alpha power and 0.94 for theta/alpha ratio), sensitivity was generally much lower. Conclusions: Early EEG slowing is a specific feature of MCI-LB compared to MCI-AD. However, there is an overlap between the two MCI groups which makes it difficult to distinguish between them based on EEG alone.
Paranamixis aberro Hirayama 1983
Creators: name: White, Kristine N.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Leucothoidae
Paranamixis
Paranamixis aberro

description: Paranamixis aberro Hirayama, 1983
 Paranamixis aberro Hirayama, 1983: 143–146, figs 36, 37. — Thomas, 1997: 82, 83.
 Type locality and specimens. Shijiki Bay, West Kyushu, Japan. Holotype, anamorph male, 4.0 mm.
 Material examined. No material available for examination. Diagnosis based on description by Hirayama (1983) and Thomas (1997).
 Diagnosis. Anterior head margin with concavity. Gnathopod 2 coxa expanded; basis with triangular process on anteroproximal margin; propodus posteriorly excavate with 3 teeth.
 Leucomorph (juvenile/sexually dimorphic characters). Unknown.
 Habitat. Habitat and depth not recorded.
 Host. Unknown.
 Distribution. East China Sea: Shijiki Bay, West Kyushu, Japan (Hirayama 1983; Thomas 1997).
description: Published as part of White, Kristine N., 2011, A taxonomic review of the Leucothoidae (Crustacea: Amphipoda) 3078, pp. 1-113 in Zootaxa 3078 (1) on page 27, DOI: 10.11646/zootaxa.3078.1.1, http://zenodo.org/record/5243821