cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Simplified Assessment Procedure to Determine the Seismic Vulnerability of Reinforced Concrete Bridges in Indiana
Creators: name: Mahmud, Farida Ikpemesi
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Civil engineering not elsewhere classified
Earthquake engineering

description: The possibility of earthquakes in Indiana due to the presence of the New Madrid Seismic Zone is well known. However, the identification of the Wabash Valley Seismic Zone has increased our understanding of the seismic hazard in the state of Indiana. Due to this awareness of the increased potential for earthquakes, specifically in the Vincennes District, the seismicvulnerability of Indiana’s bridge network must be assessed. As such, the objective of this thesis is to develop a simplified assessment procedure that can be used to conduct a state-wide seismic vulnerability assessment of reinforced concrete bridges in Indiana.Across the state, variability in substructure type, seismic hazard level, and soil site class influences the vulnerability of bridges. To fully understand the impact of this variation, a detailed assessment is completed on a representative sample. Twenty-five reinforced concrete bridges are selected across the state, and analyzed using information from the bridge drawings and a finite element analysis procedure. These bridges are analyzed using synthetic ground motions representative of the hazard level in Indiana. The results of the detailed analysis are used to develop a simplified assessment procedure that uses information that is available in BIAS or can be added to BIAS. At this time, BIAS does not contain all the necessary information required for accurate estimates of dynamic properties, thus, certain assumptions are made. Several candidate models are developed by incrementally increasing the level of information proposed to be added into BIAS, which resulted in an increase in the level of accuracy of the results. The simplified assessment is then validated through a comparison with the detailed analysis.Through the development of the simplified assessment procedure, the minimum data item which must be added to BIAS to complete the assessment is the substructure type, and bridges with reinforced concrete columns in the substructure require a detailed assessment. Lastly, by increasing the level of information available in BIAS, the agreement between the results of the simplified assessment and the detailed assessment is improved.
Manipulating Metacognition in Witness for the Prosecution
Creators: name: Zunshine, Lisa
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Feature films
subject: Cognition
subject: Law
subject: FOS: Law
subject: Witness for the prosecution (Motion picture)
subject: Short stories
subject: Television series
subject: Cognitive psychology
subject: Christie, Agatha, 1890-1976
subject: Fiction films

description: This essay exemplifies a cognitive approach to literary and film studies, with particular emphasis on fictional reimagining of legal institutions. It draws on research of cognitive scientists who study metacognition—specifically, the difference between reflective and intuitive beliefs—to suggest that courtroom dramas, such as Billy Wilder’s Witness for the Prosecution (1957), can manipulate their viewers into believing something that they, on some level, know cannot be true. In this case, viewers accept the not guilty verdict by the jury even though “the facts in the case” are “simple” and point to the guilt of the defendant. I show how different versions of Witness for the Prosecution—from Agatha Christie’s original short story (1925) and her subsequent play based on that story (1953), to the Hollywood film (1957), and the BBC mini-series (2016)—trigger our reflective beliefs about the defendant’s innocence, so that we find the verdict satisfying (at least for a short while). I conclude by considering literary payoffs of this manipulation, especially in the context of a culture that subscribes to a view of the mind as, in principle, knowable, and thus readable by skillful others.
A REVIEW ON SIDERITIS PLANT
Creators: name: Shaik. Sofiya*, Dr. V. Jayasankar Reddy, Dr. K. Venu Gopal, 4Dr. C. Bhuvaneswara Roa
Publisher: name: Zenodo
Year: 2024

description: Sideritis, a genus of flowering plants, has been employed for centuries in traditional medicine, folklore, and culinary practices. This review provides a comprehensive overview of Sideritis plants, encompassing their botany, phytochemistry, pharmacological activities, traditional uses, and future research directions. Sideritis plants are characterized by their aromatic leaves, stems, and flowers, containing bioactive compounds such as flavonoids, phenolic acids, terpenes, and essential oils. The genus comprises approximately 100 species, with Sideritis scardica, Sideritis raeseri, and Sideritis clandestina being the most extensively studied. Sideritis plants exhibit antimicrobial, antioxidant, anti-inflammatory, and antifungal properties, positioning them as valuable resources for addressing various health concerns. Their potential in neuroprotection, immunomodulation, and anticancer therapy warrants further exploration. Traditional knowledge and cultural significance of Sideritis plants have been well-documented. Preservation of traditional knowledge and cultural heritage is crucial for sustainable development of Sideritis-based products. Future research should focus on standardization, quality control, and clinical trials to fully elucidate Sideritis's therapeutic potential. This review highlights the multifaceted properties and applications of Sideritis plants, underscoring their potential as natural remedies for various health challenges. Further investigation is necessary to unlock the full therapeutic and commercial potential of Sideritis plants, offering opportunities for pharmaceutical, cosmetic, and food industries.

Keywords: Pharmacological activities, Neuro-protection, Immunomodulation, Bioactive compounds
Dynamic Coupling in a Model Rocket Combustor
Creators: name: Fuller, Tristan Latimer
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace engineering not elsewhere classified

description: Thermoacoustic instabilities in rocket engines have been studied for decades and models have been attempted, however, the heat release fluctuations and overall responseis still poorly understood. To understand the heat release mechanism in a rocket combustion chamber the effect of hydrodynamics and chemical kinetics on the mode/s of combustion need to be studied. Using prior simulations of the CVRC, an initial design for a new model rocket combustor was proposed. The new design improved on past experiments by having better control of all important boundary conditions; facilitate higher fidelity pressure and optical measurements with emphasis on quantifying the results and using them to validate simulation models of the design; and allow good control over the characteristic parameters of the injection mechanics. A prior simulation was done on the proposed design to allow fine tuning of thedesign elements. Three distinct modes of self-excited instability were observed in the experiment, two of which transitioned between one another with a sweep in oxidizertemperature. A number of configurations and operating conditions were tested, but the primary focus was on three oxidizer rich cases, at different oxidizer temperatures. The two extreme cases were compared to the simulations conducted. At low oxidizer temperatures there was good agreement, where at high oxidizer temperatures therewas a fairly good agreement in the type of mechanics observed, but there were a few discrepancies. The vortex shedding off of the fuel collar was captured using chemiluminescence measurements and compared quite well with the simulations. It was found that the fuel collar vortex shedding did not directly contribute to the generation ofinstabilities.
How Memories Become Literature
Creators: name: Zunshine, Lisa
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Cognitive psychology
subject: Memory
subject: Autobiography
subject: Children
subject: Cognitive science
subject: Archival resources
subject: Wolf, Christa
subject: Narration (Rhetoric)
subject: Manuscripts
subject: Germany

description: Cognitive science can help literary scholars formulate specific questions to be answered by archival research. This essay takes as its starting point embedded mental states (that is, mental states about mental states) and their role in generating literary subjectivity. It then follows the transformation of embedded mental states throughout several manuscripts of Christa Wol1’s autobiographical novel, Patterns of Childhood (Kindheitsmuster, 1976), available at the Berlin Academy of Arts. The author shows that later versions of Patterns of Childhood have more complex embedments in the chapter describing the adolescent protagonist’s relationship with her schoolteacher. This textual development is integral to the process whereby the presumably authentic memories of the past are constructed to fit the present needs of the person who is doing the remembering. Accompanying the three case studies of the manuscript revision is a discussion of theoretical and practical implications of this “cognitive-archival” approach to literature.
ADMINISTRATION OF SEX HORMONES AS DRUGS TO ATTENUATE DRUG-INDUCED LENGTHENING OF VENTRICULAR REPOLARIZATION
Creators: name: Tomaselli, Elena Muensterman
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Clinical pharmacy and pharmacy practice

description: My PhD thesis evolves around the potential protective effects of sex hormones progesterone and testosterone against drug-induced QT interval prolongation in premenopasual women and older men.
Immunogenicity and safety of HepE Hecolin® in chronic hepatitis B patients at clinically stable stage: An open-label study in China
Creators: name: Zhang, Li
name: Zhang, Qiufen
name: Liu, Jiaye
name: Wu, Wenlong
name: Jiang, Zechun
name: Yan, Bingyu
name: Cao, Qingfan
name: Liu, Haidong
name: Pan, Huirong
name: Lv, Jingjing
name: Feng, Yi
name: Xu, Fujie
name: Huang, Shoujie
name: Xu, Aiqiang
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences

description: Acute hepatitis E infection could induce severe outcomes among chronic hepatitis B (CHB) patients. Between 2016 and 2017, an open-label study was conducted to evaluate the immunogenicity and safety of hepatitis E vaccine (HepE) in CHB patients, using healthy adults as parallel controls in China. Eligible participants who were aged ≥30 y were enrolled in the study. The CHB group included participants who had ever developed symptoms of hepatitis because of CHB but was currently at a clinically stable stage, which was defined as ALT ≤ 1.5 times of upper limit of the normal range (ULN) in this study. The control group included healthy adults who had hepatitis B surface antigen (HBsAg) negative. HepE was administered for 0, 1, 6 months for all participants. At 1 month after the third-dose vaccination (month 7), the seroconversion rates of anti-HEV IgG were >97% in both groups. The geometric mean concentration (GMC) of anti-HEV IgG in the CHB group was non-inferior to the healthy adult group (0.69 WU/mL, 95% CI 0.55–0.85). The proportion of the participants with adverse events ≥ grade 3 was similar in both groups (p = .99), and no vaccine-associated severe adverse events were identified. Changes in the liver function indicators were not of clinical significance. The HepE was highly immunogenic and well tolerated among clinically stable CHB patients and healthy adults.
sj-pdf-1-han-10.1177_15589447211028924 – Supplemental material for Dorsoradial Ligament Reconstruction in Trapeziometacarpal Joint Arthritis
Creators: name: Kittithamvongs, Piyabuth
name: Uerpairojkit, Chairoj
name: Wangtanabadeekul, Saksri
name: Anantavorasakul, Navapong
name: Malungpaishrope, Kanchai
name: Leechavengvongs, Somsak
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Medicine
subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-han-10.1177_15589447211028924 for Dorsoradial Ligament Reconstruction in Trapeziometacarpal Joint Arthritis by Piyabuth Kittithamvongs, Chairoj Uerpairojkit, Saksri Wangtanabadeekul, Navapong Anantavorasakul, Kanchai Malungpaishrope and Somsak Leechavengvongs in HAND
"The Grand Event for Which They Are Born": Life, Death, and Eternity in the Poetry of Ann and Jane Taylor
Creators: name: Smulders, Sharon
Publisher: name: Humanities Commons
Year: 2007
Subjects: subject: Children's literature
subject: Children's poetry, English
subject: Children's literature, English
subject: Christian literature for children
subject: Hymns, English
subject: Death
subject: Women in literature
subject: Taylor, Ann, 1782-1866
subject: Taylor, Jane, 1783-1824
subject: Women poets

description: Death pervades the juvenile poetry of Ann and Jane Taylor. Despite their commitment to the pedagogy of death, however, a singular lack of spiritual content or religious consolation distinguishes their first and, in many ways, their most famous works, Original Poems for Infant Minds (1804-1805) and Rhymes for the Nursery (1806). At the same time, their later volumes, Hymns for Infant Minds (1810) and Original Hymns for Sunday Schools (1812), witness a significant teleological shift in orientation from behaviour to belief, from body to soul, and from the here to the hereafter. By so resituating themselves as female hymnists and popular theologians, the Taylor sisters not only subordinate juvenile poetry to the imperatives of evangelical mission but also give shape to nineteenth-century notions of death, damnation, and divinity.
Additional file 1 of Decreased physical performance despite objective and subjective maximal exhaustion in post-COVID-19 individuals with fatigue
Creators: name: Vollrath, Shirin
name: Matits, Lynn
name: Schellenberg, Jana
name: Kirsten, Johannes
name: Steinacker, Jürgen M.
name: Bizjak, Daniel A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health

description: Additional file 1: Table S1. Influence of confounders on the correlation between both groups for the variables Peak V̇O2/BM (Volume Oxygen/Body Mass), Max Power/BM (Maximal Power/BM), Max. lactate (maximum lactate), Peak HR (Peak Heart Rate).
Modernism and Religion: Between Mysticism and Orthodoxy
Creators: name: Callison, Jamie
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Modernism (Literature)
subject: Religion and literature
subject: Postsecularism
subject: Secularization
subject: Poetics
subject: Mysticism
subject: Spirituality
subject: Eliot, T. S. (Thomas Stearns), 1888-1965
subject: H. D. (Hilda Doolittle), 1886-1961
subject: Jones, David, 1895-1974

description: 'Modernism and Religion' argues that modernism participated in broader processes of religious change in the twentieth century. The new prominence accorded to immanence and immediacy in religious discourse is carried over into the modernist epiphany. Modernism became mystical. The emergence of Catholic theological modernism, human rights, Christian sociology, and philosophical personalism, which are explored here in relation to the work of David Jones, T. S. Eliot, and H.D., represented a strategic attempt on the part of diverse religious authorities to meet the challenge posed by new mysticism. Orthodoxy was itself made new in ways that resisted the secular demand that religion remain a private undertaking. Modernism and Religion presents the mechanical form and clashing registers of long poems by each of the aforementioned writers as an alternative to epiphanic modernism. Their wavering orthodoxy brings matters from which the secular had previously separated religion back once more into its purview.
“I Have a Dream”: Erasing American Ecophobia *
Creators: name: Christman, Sophie
Publisher: name: Humanities Commons
Year: 2019
Subjects: subject: Silent spring (Carson, Rachel)
subject: Ecocriticism in literature
subject: I have a dream (King, Martin Luther, Jr.)
subject: United States. Environmental Protection Agency
subject: Constitution (United States)
subject: Union of Concerned Scientists
subject: Green New Deal
subject: Political ecology

description: Considering the institutionalized forms of ecophobia in the United States, is it necessary to enact a Civil Rights of Nature? I claim that conceptually linking the Constitutional protections enabled by the American civil rights movement to an emerging civil rights of nature would enable the rapid transition away from ecophobic attitudes toward anti-naturism laws that help restore, redress, and revitalize US ecologies. After all, since the US Constitution secures for Americans a “Supreme Law of the Land,” shouldn’t that law of the land protect the environment on which it is anchored?
Additional file 1 of Antibacterial peptide PMAP-37(F34-R), expressed in Pichia pastoris, is effective against pathogenic bacteria and preserves plums
Creators: name: Dong, Chunming
name: Xu, Lijun
name: Lu, Weitao
name: Li, Mengru
name: Zhang, Rui
name: Sun, Yanyan
name: Liu, Jian
name: Chu, Xinlei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1: The plasmid map of pPICZ?A-PMAP-37(F34-R)
* The Rise of Proto-Environmentalism in George Eliot
Creators: name: Christman, Sophie
Publisher: name: Humanities Commons
Year: 2019
Subjects: subject: Eliot, George, 1819-1880
subject: Poetry
subject: Browning, Robert, 1812-1889
subject: Browning, Elizabeth Barrett, 1806-1861
subject: Ecotheology
subject: Thermodynamics
subject: Bible. Minor Prophets
subject: Bible. Malachi

description: The “Ilfracombe” journals, “Ex Oriente Lux,” and “A Minor Prophet” register the ways  in which George Eliot’s nineteenth-century nonfiction prose and poetry evidence  ecotheological concerns that are proto-environmental, concerns that are also  reflected in some of her novels. Employing an ecocritical methodology, this article  traces the development of Eliot’s ecological literacy, beginning with her scientific  field observations that incubated what would become her lifelong literary aesthetic  of moral sympathy put forth in “The Natural History of German Life.” Eliot’s initial  moral sympathy advanced to an ecotheological perspective made visible in both  Eliot’s unpublished lyric poem “Ex Oriente Lux” and her canonic verse “A Minor  Prophet.” Eliot’s early and mature writings countervailed the competing discourses of  theology and science as they relate to the natural environment.
TRANSITION METAL CATALYZED SIMMONS–SMITH TYPE CYCLOPROPANATIONS
Creators: name: Werth, Jacob J
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Catalysis and mechanisms of reactions
Organic chemistry not elsewhere classified
Organometallic chemistry

description: Cyclopropanes are commonly found throughout synthetic and natural biologically active compounds. The Simmons–Smith cyclopropanation reaction is one of the most useful methods for converting an alkene into a cyclopropane. Zinc carbenoids are the active intermediate in the reaction, capable of delivering the methylene unit to a broad variety of substrates. Significant advances have been made in the field to increase overall efficiency of the reaction including the use of diethyl zinc as a precursor and allylic alcohols as directing groups.Despite the many notable contributions in zinc carbenoid chemistry, persistent limitations of the Simmons–Smith reaction still exist. Zinc carbenoids exhibit poor steric discrimination in the presence of a polyolefin with minimal electronic bias. Additionally, due to the electrophilic nature of zinc carbenoid intermediates, the reaction performs inefficiently with electron-deficient olefins. Finally, alkyl-substituted zinc carbenoids are known to be quite unstable, limiting the potential for substituted cyclopropanation reactions.In this work, we demonstrate that cobalt catalysis can be utilized to access novel cyclopropane products through the activation of dihaloalkanes. The content of this thesis will focus on the limitations of Zn carbenoid chemistry and addressing them with cobalt catalyzed, reductive cyclopropanations. In addition to this reactivity, we also demonstrate the dimethylcyclopropanation of activated alkenes to furnish valuable products applicable to natural product synthesis and pharmaceutically relevant compounds. Finally, we will show the unique character of the cobalt catalyzed cyclopropanation reaction through mechanistic experiments and characterization of reaction intermediates. In whole, these studies offer a complementary method to zinc carbenoid chemistry in producing novel and diverse cyclopropane products.
Supplemental Material, sj-pdf-6-vet-10.1177_03009858211013712 - International Guidelines for Veterinary Tumor Pathology: A Call to Action
Creators: name: Meuten, Donald J.
name: Moore, Frances M.
name: Donovan, Taryn A.
name: Bertram, Christof A.
name: Klopfleisch, Robert
name: Foster, Robert A.
name: Smedley, Rebecca C.
name: Dark, Michael J.
name: Milovancev, Milan
name: Stromberg, Paul
name: Williams, Bruce H.
name: Aubreville, Marc
name: Avallone, Giancarlo
name: Bolfa, Pompei
name: Cullen, John
name: Dennis, Michelle M.
name: Goldschmidt, Michael
name: Luong, Richard
name: Miller, Andrew D.
name: Miller, Margaret A.
name: Munday, John S.
name: Roccabianca, Paola
name: Salas, Elisa N.
name: Schulman, F. Yvonne
name: Laufer-Amorim, Renee
name: Asakawa, Midori G.
name: Craig, Linden
name: Dervisis, Nick
name: Esplin, D. Glen
name: George, Jeanne W.
name: Hauck, Marlene
name: Kagawa, Yumiko
name: Kiupel, Matti
name: Linder, Keith
name: Meichner, Kristina
name: Marconato, Laura
name: Oblak, Michelle L.
name: Santos, Renato L.
name: Simpson, R. Mark
name: Tvedten, Harold
name: Whitley, Derick
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental Material, sj-pdf-6-vet-10.1177_03009858211013712 for International Guidelines for Veterinary Tumor Pathology: A Call to Action by Donald J. Meuten, Frances M. Moore, Taryn A. Donovan, Christof A. Bertram, Robert Klopfleisch, Robert A. Foster, Rebecca C. Smedley, Michael J. Dark, Milan Milovancev, Paul Stromberg, Bruce H. Williams, Marc Aubreville, Giancarlo Avallone, Pompei Bolfa, John Cullen, Michelle M. Dennis, Michael Goldschmidt, Richard Luong, Andrew D. Miller, Margaret A. Miller, John S. Munday, Paola Roccabianca, Elisa N. Salas, F. Yvonne Schulman, Renee Laufer-Amorim, Midori G. Asakawa, Linden Craig, Nick Dervisis, D. Glen Esplin, Jeanne W. George, Marlene Hauck, Yumiko Kagawa, Matti Kiupel, Keith Linder, Kristina Meichner, Laura Marconato, Michelle L. Oblak, Renato L. Santos, R. Mark Simpson, Harold Tvedten and Derick Whitley in Veterinary Pathology
sj-pdf-1-pss-10.1177_0956797621996663 – Supplemental material for Mutual Information and Categorical Perception
Creators: name: Feldman, Jacob
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-1-pss-10.1177_0956797621996663 for Mutual Information and Categorical Perception by Jacob Feldman in Psychological Science
Foreword
Creators: name: Christman, Sophie
Publisher: name: Routledge
Year: 2018
Subjects: subject: Freud, Sigmund, 1856-1939
subject: International Union of Geological Sciences. Commission on Stratigraphy. Anthropocene Working Group
subject: Beethoven, Ludwig van, 1770-1827
subject: Phobias
subject: Wilson, Edward O.
subject: Evolution (Biology)

description: A STEAM-informed humanities' essay describing the theoretical concept of "ecophobia"-a notion put forward in Simon Estok's theoretical text The Ecophobia Hypothesis (Routledge 2018) that describes the systemic human fear of nature.
sj-pdf-1-aop-10.1177_10600280211033938 – Supplemental material for Impact of Proton Pump Inhibitor Use on the Effectiveness of Immune Checkpoint Inhibitors in Advanced Cancer Patients
Creators: name: Peng, Kangning
name: Chen, Ken
name: Teply, Benjamin A.
name: Yee, Gary C.
name: Farazi, Paraskevi A.
name: Lyden, Elizabeth R.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-aop-10.1177_10600280211033938 for Impact of Proton Pump Inhibitor Use on the Effectiveness of Immune Checkpoint Inhibitors in Advanced Cancer Patients by Kangning Peng, Ken Chen, Benjamin A. Teply, Gary C. Yee, Paraskevi A. Farazi and Elizabeth R. Lyden in Annals of Pharmacotherapy
Improving the Utility of Egocentric Videos
Creators: name: Ma, Biao
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Image processing
Computer vision

description: For either entertainment or documenting purposes, people are starting to record their life using egocentric cameras, mounted on either a person or a vehicle. Our target is to improve the utility of these egocentric videos.
For egocentric videos with an entertainment purpose, we aim to enhance the viewing experience to improve overall enjoyment. We focus on First-Person Videos (FPVs), which are recorded by wearable cameras. People record FPVs in order to share their First-Person Experience (FPE). However, raw FPVs are usually too shaky to watch, which ruins the experience. We explore the mechanism of human perception and propose a biometric-based measurement called the Viewing Experience (VE) score, which measures both the stability and the First-person Motion Information (FPMI) of a FPV. This enables us to further develop a system to stabilize FPVs while preserving their FPMI. Experimental results show that our system is robust and efficient in measuring and improving the VE of FPVs.
For egocentric videos whose goal is documentation, we aim to build a system that can centrally collect, compress and manage the videos. We focus on Dash Camera Videos (DCVs), which are used by people to document the route they drive each day. We proposed a system that can classify videos according to the route they drove using GPS information and visual information. When new DCVs are recorded, their bit-rate can be reduced by jointly compressing them with videos recorded on the similar route. Experimental results show that our system outperforms other similar solutions and the standard HEVC particularly in varying illumination.
The First-Person Video viewing experience topic and the Dashcam Video compression topic are two representations of applications rely on Visual Odometers (VOs): visual augmentation and robotic perception. Different applications have different requirement for VOs. And the performance of VOs are also influenced by many different factors. To help our system and other users that also work on similar applications, we further propose a system that can investigate the performance of different VOs under various factors. The proposed system is shown to be able to provide suggestion on selecting VOs based on the application.
* Bustin’ Bonaparte: A Post-Apartheid Adaptation of Olive Schreiner’sThe Story of an African Farm
Creators: name: Christman, Sophie
Publisher: name: Humanities Commons
Year: 2016
Subjects: subject: Race
subject: Schreiner, Olive, 1855-1920
subject: South Africa
subject: Post-apartheid era
subject: Children\'s films

description: This article examines how the South African film Bustin’ Bonaparte (2004) presents a  post-apartheid adaptation of Victorian colonialism in Olive Schreiner’s 1883 English novel The Story  of an African Farm. While both narratives utilize the surprising mode of play to unfold competing  racial and gender hierarchies in colonial Africa, Lister’s comedic film radically revises Schreiner’s  tragic novel to witness the hopeful post-apartheid nationalism of Africa’s children.
sj-pdf-1-acr-10.1177_02841851211032441 - Supplemental material for Different cerebral functional segregation in Sjogren’s syndrome with or without systemic lupus erythematosus revealed by amplitude of low-frequency fluctuation
Creators: name: Zhang, Xiao-Dong
name: Ke, Jun
name: Li, Jing-Li
name: Su, Yun-Yan
name: Zhou, Jia-Min
name: Zhao, Lin-Ru
name: Huang, Li-Xiang
name: Cheng, Yue
name: Shen, Wen
Publisher: name: SAGE Journals
Year: 2021
Subjects: Radiology and Organ Imaging

description: Supplemental material, sj-pdf-1-acr-10.1177_02841851211032441 for Different cerebral functional segregation in Sjogren’s syndrome with or without systemic lupus erythematosus revealed by amplitude of low-frequency fluctuation by Xiao-Dong Zhang, Jun Ke, Jing-Li Li, Yun-Yan Su, Jia-Min Zhou, Lin-Ru Zhao, Li-Xiang Huang, Yue Cheng and Wen Shen in Acta Radiologica
Mapping the rapid growth of multi-omics in tumor immunotherapy: Bibliometric evidence of technology convergence and paradigm shifts
Creators: name: Dong, Huijing
name: Wang, Xinmeng
name: Zheng, Yumin
name: Li, Jia
name: Liu, Zhening
name: Wang, Aolin
name: Shen, Yulei
name: Wu, Daixi
name: Cui, Huijuan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Science Policy

description: This study aims to fill the knowledge gap in systematically mapping the evolution of omics-driven tumor immunotherapy research through a bibliometric lens. While omics technologies (genomics, transcriptomics, proteomics, metabolomics)provide multidimensional molecular profiling, their synergistic potential with immunotherapy remains underexplored in large-scale trend analyses. A comprehensive search was conducted using the Web of Science Core Collection for literature related to omics in tumor immunotherapy, up to August 2024. Bibliometric analyses, conducted using R version 4.3.3, VOSviewer 1.6.20, and Citespace 6.2, examined publication trends, country and institutional contributions, journal distributions, keyword co-occurrence, and citation bursts. This analysis of 9,494 publications demonstrates rapid growth in omics-driven tumor immunotherapy research since 2019, with China leading in output (63% of articles) yet exhibiting limited multinational collaboration (7.9% vs. the UK’s 61.8%). Keyword co-occurrence and citation burst analyses reveal evolving frontiers: early emphasis on “PD-1/CTLA-4 blockade” has transitioned toward “machine learning,” “multi-omics,” and “lncRNA,” reflecting a shift to predictive modeling and biomarker discovery. Multi-omics integration has facilitated the development of immune infiltration-based prognostic models, such as TIME subtypes, which have been validated across multiple tumor types, which inform clinical trial design (e.g. NCT06833723). Additionally, proteomic analysis of melanoma patients suggests that metabolic biomarkers, particularly oxidative phosphorylation and lipid metabolism, may stratify responders to PD-1 blockade therapy. Moreover, spatial omics has confirmed ENPP1 as a potential novel therapeutic target in Ewing sarcoma. Citation trends underscore clinical translation, particularly mutation-guided therapies. Omics technologies are transforming tumor immunotherapy by enhancing biomarker discovery and improving therapeutic predictions. Future advancements will necessitate longitudinal omics monitoring, AI-driven multi-omics integration, and international collaboration to accelerate clinical translation. This study presents a systematic framework for exploring emerging research frontiers and offers insights for optimizing precision-driven immunotherapy.
sj-docx-1-onc-10.1177_11795549211032330 – Supplemental material for High expression of cluster of differentiation 276 indicates poor prognosis in glioma
Creators: name: Li, Linchen
name: Zhang, Min
name: Zhu, Dengna
name: Wang, Xinjun
Publisher: name: SAGE Journals
Year: 2021
Subjects: Oncology and Carcinogenesis not elsewhere classified

description: Supplemental material, sj-docx-1-onc-10.1177_11795549211032330 for High expression of cluster of differentiation 276 indicates poor prognosis in glioma by Linchen Li, Min Zhang, Dengna Zhu and Xinjun Wang in Clinical Medicine Insights: Oncology
Alt-Burger: Transforming Populist Food Systems
Creators: name: Christman, Sophie
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Bob's Burgers (Television program)
subject: Climatic changes
subject: Factory farms
subject: Food habits
subject: Food supply
subject: Food industry and trade

description: This article argues that there exists a problematic nexus between the industrial livestock industry, US food system policies, and American propagandist literature. The essay’s specific aim is to transform carnivorous appetites by subverting the integrity of America’s national gastronomic emblem – the hamburger. The article examines how hamburgers are unsustainable food system commodities that exacerbate state-sanctioned climate change, analyzes the underpinnings of ecophobic beef literature—specifically the graphic narrative—that serves as state propaganda, and shows how American comics can alternately promote sustainability nexuses by creating awareness of how food systems impact climate change.
PD-1/PD-L1 inhibitors related adverse events: A bibliometric analysis from 2014 to 2024
Creators: name: Song, Qingya
name: Yu, Zongliang
name: Lu, Wenping
name: Zhuo, Zhili
name: Chang, Lei
name: Mei, Heting
name: Cui, Yongjia
name: Zhang, Dongni
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Programmed cell death-1 (PD-1) inhibitors and programmed cell death ligand 1 (PD-L1) inhibitors are considered effective alternatives for the primary treatment of recurrent metastatic cancers. However, they can induce various adverse events affecting multiple organ systems, potentially diminishing patients’ quality of life, and even leading to treatment interruptions. Adverse events related to PD-1/PD-L1 inhibitors differ from those associated with CTLA-4 inhibitors and are more commonly observed in the treatment of solid tumors. This study aimed to address the knowledge gap regarding adverse events related to PD-1/PD-L1 inhibitors. A visual bibliometric network was constructed using VOSviewer, CiteSpace, R software, and the Web of Science Core Collection (WoSCC) to quantitatively analyze this research field. Future research directions were also explored. The USA ranked first in publication count and total citations. Over time, publication types transitioned from case reports to clinical trials. Research on for nivolumab was the most prevalent. The spectrum of cancers treated by PD-1/PD-L1 inhibitors expanded beyond melanoma and lung cancer to include renal cell carcinoma, esophageal cancer, and others. Common adverse events included pneumonitis, myasthenia gravis, and vitiligo. There was a significant increase in multi-phase clinical trials and studies related to biomarkers. This study offers valuable insights for potential collaborators and institutions, highlighting trends in the study of adverse events related to PD-1/PD-L1 inhibitors. The management of these adverse events has become more refined and standardized. Biomarker research and multi-phase clinical trials are likely to be key areas of focus in future studies.
Abandoning Tragedy in James Ijames Fat Ham
Creators: name: Alfar, Cristina León
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Drama
subject: Queer theory
subject: Hamlet (Shakespeare, William)
subject: Appropriation (Arts)
subject: Feminism and literature
subject: Black people--Race identity

description: The story of William Shakespeare’s Hamlet is adapted and revised by James Ijames in his play Fat Ham, which ran from 12 May to 31 July 2022 at The Public Theater, coproduced by the National Black Theatre. Ijames’s play, which won the 2022 Pulitzer Prize for drama, plays with and departs from the plot of Hamlet to explore Black manhood, the family, and cycles of violence that are broken by love. Rejecting generic constraints demanded by tragedy — male violence and misogyny, and compliant and sacrificial women — the play stages a celebration of love, friendship, forgiveness, compassion, and queer pride.
Additional file 4 of CircRNAs in diagnosis, prognosis, and clinicopathological features of multiple myeloma; a systematic review and meta-analysis
Creators: name: Mirazimi, Yasin
name: Aghayan, Amir Hossein
name: Keshtkar, Abbasali
name: Mottaghizadeh Jazi, Mahsa
name: Davoudian, Atefeh
name: Rafiee, Mohammad
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Additional file 4: Figure S1. Forest plots of DS stage (A), ISS stage (B), B2-MG (C), del(17p) (D) and t(4;14) (E) in the clinicopathological features association analysis with circRNAs in MM patients. Figure S2 Forest plots of other clinicopathological parameters.
Quantitative Models of Calcium-Dependent Protein Signaling in Neuronal Dendritic Spines
Creators: name: Pharris, Matthew C
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Biomedical engineering not elsewhere classified

description: Worldwide, as many as 1 billion people suffer from neurological disorders. Fundamentally, neurological disorders are caused by dysregulation of biochemical signaling within neurons, leading to deficits in learning and memory formation. To identify better preventative and therapeutic strategies for patients of neurological disorders, we require a better understanding of how biochemical signaling is regulated within neurons. Biochemical signaling at the connections between neurons, called synapses, regulates dynamic shifts in a synapse’s size and connective strength. Called synaptic plasticity, these shifts are initiated by calcium ion (Ca2+) flux into message-receiving structures called dendritic spines. Within dendritic spines, Ca2+ binds sensor proteins such as calmodulin (CaM). Importantly, Ca2+/CaM may bind and activate a wide variety of proteins, which subsequently facilitate signaling pathways regulating the dendritic spine’s size and connective strength. In this thesis, I use computational models to characterize molecular mechanisms regulating Ca2+-dependent protein signaling within the dendritic spine. Specifically, I explore how Ca2+/CaM differentially activates binding partners and how these binding partners transduce signals downstream. For this, I present deterministic models of Ca2+, CaM, and CaM-dependent proteins, and in analyzing model output I demonstrate in-part that competition for CaM-binding alone may be sufficient to set the Ca2+ frequency-dependence of protein activation. Subsequently, I adapt my deterministic models into particle-based, spatial-stochastic frameworks to quantify how spatial effects influence model output, showing evidence that spatial gradients of Ca2+/CaM may set spatial gradients of activated proteins downstream. Additionally, I incorporate into my models the most detailed model to-date of Ca2+/CaM-dependent protein kinase II (CaMKII), a multi-subunit protein essential to synaptic plasticity. With this detailed model of CaMKII, my analysis suggests that the many subunits of CaMKII provide avidity effects that significantly increase the protein’s effective affinity for binding partners, particularly Ca2+/CaM. Altogether, this thesis provides a detailed analysis of Ca2+-dependent signaling within dendritic spines, characterizing molecular mechanisms that may be useful for the development of novel therapeutics for patients of neurological disorders.
Lack of an effect of a commercial vaccine adjuvant on the development of postweaning multisystemic wasting syndrome (PMWS) in porcine circovirus type 2 (PCV2) experimentally infected conventional pigs
Creators: name: Resendes, Ana
name: Segalés, Joaquim
name: Balasch, Mònica
name: Calsamiglia, Maria
name: Sibila, Marina
name: Ellerbrok, Heinz
name: Mateu, Enric
name: Plana-Durán, Joan
name: Mankertz, Annette
name: Domingo, Mariano
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2004
Subjects: subject: porcine circovirus type 2 (PCV2)
subject: pigs
subject: vaccine adjuvant
subject: real-time quantitative PCR
subject: in situ hybridisation
subject: 610 Medizin

description: The objective of this study was to evaluate the effect of a commercial vaccine adjuvant on the clinical and pathological outcome of PCV2 experimentally infected 8 to 9-week-old conventional pigs. Forty-four pigs were divided into four groups: non-infected control pigs, pigs that received a vaccine adjuvant, pigs inoculated with PCV2, and pigs inoculated with PCV2 together with the vaccine adjuvant. Infection was monitored until 69 days post-inoculation (PI). Some PCV2 inoculated pigs had hyperthermia, but no other clinical signs were recorded. No characteristic PMWS gross or microscopic lesions were observed in any of the pigs. PCV2 DNA was detected in lymphoid tissues by in situ hybridisation in 6 PCV2 inoculated pigs on day 69 PI. All PCV2 inoculated pigs seroconverted between days 21 and 49 PI, shortly after viremia detection. Moreover, viremia was detected between days 7 and 69 PI using PCR. A peak of the virus load was detected by real-time quantitative PCR between days 14 and 21 PI. There were no significant differences in the proportion of PCV2 positive serum and in the viral load between PCV2 and PCV2 + adjuvant inoculated pigs. Although PMWS was not reproduced in neither PCV2 nor PCV2 + adjuvant inoculated pigs, viremia detection and seroconversion indicated that all PCV2 inoculated pigs developed a chronic long-term asymptomatic infection. An increase of PCV2 replication was not observed in pigs inoculated with the adjuvant. These results indicate that the principle of immunostimulation may not be applicable under the experimental conditions used, suggesting that not all adjuvants used in commercial vaccines are capable of triggering mechanisms for PMWS development.
Lyophilized monkeypox mRNA lipid nanoparticle vaccines with long-term stability and robust immune responses in mice
Creators: name: Wang, Bin
name: Yin, Quanyi
name: Yi, Li
name: Su, Caixia
name: Wen, Yang
name: Qiao, Man
name: Ju, Yingchen
name: Liu, Zhihua
name: Xiong, Yelin
name: Liu, Zhilei
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: The World Health Organization (WHO) has recently declared another global health emergency due to the rapidly spreading monkeypox (Mpox) outbreak in numerous African countries. To address the unmet need to contain the outbreak using the existing vaccines, this study developed a lyophilization process for an effective, scalable and affordable Mpox mRNA-LNP vaccine candidate to address the global health crisis. A comprehensive evaluation and optimization of the vaccine formulation (the type/concentration of cryoprotectants, the type/concentration of buffer system, as well as the mRNA concentration and reconstitution solvent) and the freeze-drying process parameters (freezing method, temperature, cooling rate and primary/secondary drying conditions) were conducted. The freeze-dried product exhibits a uniform appearance and a moisture content of less than 1%. Reconstitution of the lyophilized mRNA-LNP resulted in equivalent particle size/polydispersity index, encapsulation efficiency and mRNA integrity compared to that of freshly prepared mRNA-LNP. Furthermore, the lyophilization process can be scaled up 100-fold to 2000 vials/batch. Notably, the lyophilized mRNA-LNP demonstrated a storage stability of at least 12 months at 4°C, and at ambient temperature for a minimum of 8 h post-reconstitution, exhibiting minimal deterioration in product quality. The in vitro biological activity and in vivo immunogenicity of the lyophilized mRNA-LNP was comparable to that of the freshly prepared mRNA-LNP. These results provide a compelling rationale for the utilization of lyophilization technology in enhancing the accessibility of the Mpox mRNA vaccine in developing countries, a strategy that is crucial for containing the global epidemic of Mpox infection.