cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 6: of Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration
Creators: name: Aguareles, José
name: Paraíso-Luna, Juan
name: Palomares, Belén
name: Bajo-Grañeras, Raquel
name: Navarrete, Carmen
name: Ruiz-Calvo, Andrea
name: García-Rincón, Daniel
name: García-Taboada, Elena
name: Guzmán, Manuel
name: Muñoz, Eduardo
name: Galve-Roperh, Ismael
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: 3-Nitroproprionic acid model of striatal neurodegeneration. 16-week- old C57BL/6 N male mice (Harlan Ibérica, Barcelona, Spain) were subjected to seven intraperitoneal (i.p.) injections of 50 mg/kg 3-NP (one injection each every 12 h prepared in phosphate-buffered saline (PBS)]. 3-NP-treated animals and their respective non-lesioned controls (injected with PBS) were used for pharmacological studies with VCE-003.2. Treatments consisted of oral gavage every 24 h with VCE-003.2 at a dose of 10 mg/kg using sesame oil as vehicle. 12 h after the last injection of 3-NP motor activity, hindlimb clasping and kyphosis were evaluated as previously described [12]. Animals were euthanized at the indicated time after huntingtin-AAV infection or 12 h after the last injection of 3NP and their brains removed. Statistical analysis: One-way ANOVA followed by the Tuckey’s post hoc test was used to determine the statistical significance. All the in vivo data were expressed as mean ± SEM. Kruskal-Wallis test was used to determine the statistical in the case of non-parametric analysis. a) Hindlimb Clasping (F = 8.069; p = 0.0047) post hoc test: p = 0.0036 3NP vs Veh; Locomotor activity (F = 18.62; p = 0.0001) post hoc test p < 0.0001 3NP vs Veh, p = 0.0027 3NP + VCE-003.2 vs 3NP; Kyphosis (F = 28.24 p < 0.0001) post hoc test: p < 0.0001 3NP vs Veh, p < 0.0001 3NP + VCE-003.2 vs 3NP. b) TNF-α (F = 18.17 p = 0.0028) post hoc test: p = 0.0027 3NP vs Veh, p = 0.0138 3NP + VCE-003.2 vs 3NP. IL-6 (Kruskal-Wallis statistic = 6.880 p = 0.0071) post hoc test: p = 0.0265 3NP vs Veh. c) Average number of neurons per field (F = 15.69 p = 0.0012) post hoc test: p = 0.0011 3NP vs Veh, p = 0.0086 3NP + VCE-003.2 vs 3NP; Number of Iba1+ cells (F = 10.82 p = 0.0040) post hoc test: p = 0.0101 3NP vs Veh, p = 0.0059 3NP + VCE-003.2 vs 3NP. (PDF 325 kb)
Reheating Constraints on Inflaton, Dark Matter: Swampland Conjecture
Creators: name: Haque, Md Riajul
name: Maity, Debaprasad
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper, we studied the phenomenological consequences of recently proposed swampland conjecture on the inflationary models though constraints on reheating. If dark matter is assumed to be produced during reheating, the conjecture will provide further constraints on the dark matter parameter space through its current relic abundance. As has been pointed out already and also analyzed in our present paper any successful inflationary scenario is in clear tension with the aforementioned conjecture in its current form. However considering the swampland parameters to be free and constrained by the inflationary observables, we studied in detail its consequence on the reheating and dark matter phenomenology. We point out the connection between swampland conjecture and the scalar spectral index $n_s$ by PLANCK within current $2 σ$ range, and associated constraints imposed on the reheating temperature and the dark matter annihilation cross-section.
description: 18 pages, 4 figures, 1 table
Supergravity Couplings of Noncommutative D-branes
Creators: name: Liu, Hong
name: Michelson, Jeremy
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the supergravity couplings of noncommutative D-branes by considering the disk amplitudes with one closed string insertion. The result confirms a recent proposal for the general form of the noncommutative Yang-Mills operators coupling to the massless closed string modes. The construction involves smearing Yang-Mills field variables along an open Wilson line. For multiple D-branes interacting with background supergravity fields, this prescription reduces, in the B=0 limit, to the ``symmetrized trace'' prescription, and the supergravity fields are seen to be functionals of the nonabelian scalar fields on the branes.
description: 26 pages, AMSLaTeX using JHEP.cls. (REVTeX optional); v2: minor misprints corrected
title: Geschlechterpolitische Perspektiven für einen demokratischen Neubeginn in Syrien
Creators: name: Löw, Christine
Publisher: name: DuEPublico
Year: 2025
Subjects: classificationCode: 5
subject: FOS: Social sciences
subject: Gender Studies
classificationCode: 5.6
subject: FOS: Political science

description: Angesichts der akuten Bedrohungen für die demokratische autonome Selbstverwaltung in Nordostsyrien (DAANES), die sich an Geschlechterbefreiung, Ökologie und Basisdemokratie orientiert, stellt sich aktuell die Frage nach der Bedeutung des Gesellschaftsmodells für politische Entwicklungen Syriens. In transnational feministischen Kontexten gilt das als Rojava bekannte Zusammenleben verschiedener Bevölkerungsgruppen, Konfessionen sowie politischer Ausrichtungen als gelebte Utopie und sich stetig fortentwickelndes gesellschaftliches Befreiungsprojekt gegen Staat, Patriarchat und Kapitalismus (Herausgeber_innenkollektiv 2020; Exo 2019). Seit 2012, als sich das Regime von Baschar Al-Assad nach erbittertem Widerstand aus Nord- und Ostsyrien zurückgezogen hat, ist es Frauen* unter kurdischer Führung gelungen, paritätische politische Entscheidungen, wirtschaftliche Autonomie, Rechtsreformen sowie anti-patriarchalen gesellschaftlichen Wandel zu erkämpfen und institutionell in einzigartiger Weise umzusetzen (Dirik 2022a).
Renormalization on the fuzzy sphere
Creators: name: Hatakeyama, Kohta
name: Tsuchiya, Asato
name: Yamashiro, Kazushi
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study renormalization on the fuzzy sphere, which is a typical example of non-commutative spaces. We numerically simulate a scalar field theory on the fuzzy sphere, which is described by a Hermitian matrix model. We define correlation functions by using the Berezin symbol and show that they are made independent of the matrix size, which plays a role of a UV cutoff, by tuning one parameter of the theory. We also find that the theories on the phase boundary are universal. They behave as a conformal field theory at short distances, while they universally differ from it at long distances due to the UV/IR mixing.
description: 7 pages, 4 figures, Proceedings of The 36th Annual International Symposium on Lattice Field Theory (Lattice 2018), July 22-28, 2018, East Lansing, Michigan, USA
Testing nonlocal gravity with Lunar Laser Ranging
Creators: name: Belgacem, Enis
name: Finke, Andreas
name: Frassino, Antonia
name: Maggiore, Michele
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the impact of the limit on $|\dot{G}|/G$ from Lunar Laser Ranging on "nonlocal gravity", i.e. on models of the quantum effective action of gravity that include nonlocal terms relevant in the infrared, such as the "RR" and "RT" models proposed by our group, and the Deser-Woodard (DW) model. We elaborate on the analysis of Barreira et al. [1] and we confirm their findings that (under plausible assumptions such as the absence of strong backreaction from non-linear structures), the RR model is ruled out. We also show that the mechanism of "perfect screening for free" suggested for the DW model actually does not work and the DW model is also ruled out. In contrast, the RT model passes all phenomenological consistency tests and is still a viable candidate.
description: 46 pages, 4 figures
Quark condensate in a magnetic field
Creators: name: Shushpanov, I. A.
name: Smilga, A. V.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the dependence of quark condensate $Σ$ on an external magnetic field. For weak fields, it rises linearly with the field. Pion mass and residue are also shifted so that the Gell-Mann - Oakes - Renner relation is satisfied. In the strong field region, $Σ(H) \propto (eH)^{3/2}$.
description: 13 pages LaTeX, 5 postscript files for figures
Additional file 4: of Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration
Creators: name: Aguareles, José
name: Paraíso-Luna, Juan
name: Palomares, Belén
name: Bajo-Grañeras, Raquel
name: Navarrete, Carmen
name: Ruiz-Calvo, Andrea
name: García-Rincón, Daniel
name: García-Taboada, Elena
name: Guzmán, Manuel
name: Muñoz, Eduardo
name: Galve-Roperh, Ismael
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: AMES Data Summary. AMES Experimental Procedure. Approximately ten million bacteria are exposed in triplicate to VCE-003-.2 (7.8, 15.6, 31.3, 62.5, 125 and 250 μg/ml), a negative control (vehicle) and a positive control for 90 min in medium containing a low concentration of histidine (sufficient for about 2 doublings). The cultures were then diluted into indicator medium lacking histidine and dispensed into 48 wells of a 384 well plate (micro-plate format, MPF). The plate was incubated for 48 h at 37 °C, and the number of wells showing growth were counted and compared to the vehicle control. An increase in the number of colonies of at least two-fold over baseline (mean + SD of the vehicle control) and a dose response indicates a positive response. An unpaired, one-sided Student’s T-test was used to identify conditions that are significantly different from the vehicle control. Where indicated, S9 fraction from the livers of Aroclor 1254-treated rats was included in the incubation at a final concentration of 4.5%. An NADPH-regenerating system is also included to ensure a steady supply of reducing equivalents. The strains used in this study were S. typhimurium TA98 (hisD3052, rfa, uvrB/pKM10 for detection of frame-shift mutations) and S. typhimurium TA100 (hisG45, rfa, uvrB/pKM101 for detection of base-pair substitutions). VCE-003.2 was assessed for its mutagenic potential in the AMES reverse mutation assay. This test was performed in the absence and presence of S9 metabolic activation. VCE-003.2 was found to be negative for genotoxicity in this AMES study. The positive controls all behaved as expected. (PDF 568 kb)
Amorphous carbons in view of multianalytical consideration: normal, expected, and new
Creators: name: Golubev, Ye. A.
name: Rozhkova, N. N.
name: Kabachkov, E. N.
name: Shulga, Yu. M.
name: Natkaniec-Holderna, K.
name: Natkaniec, I.
name: Antonets, I. V.
name: Makeev, B. A.
name: Popova, N. A.
name: Popova, V. A.
name: Sheka, E. F.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The approach based on selected set of samples and selected set of analytical tools occurred quite efficient when applying to amorphous carbons thus leading to a transformation of the current representation of the issue based on particulars into that one based on a limited set of fixed commonalities. The approach first part implies a set of different origin solid samples. The second part concerns different analytical tools. The combining part means the application of each tool to the whole set of samples. In the current study two natural amorphous carbons shungite carbon and antraxolite, as well as two engineered products carbon blacks CB632 and CB624, all of the four belonging to the elitist highest-carbon-content species, were subjected to analytical study by using modern structural and compositional analytical techniques. The approach has allowed disclosing steady points that are common to the whole class of this carbon allotrope and that may lay the foundation of a consolidate representation of what are amorphous carbons.
description: 27 pages, 15 figures, 9 tables, 95 references
Precision distances to dwarf galaxies and globular clusters from Pan-STARRS1 3$π$ RR Lyrae
Creators: name: Hernitschek, Nina
name: Cohen, Judith G.
name: Rix, Hans-Walter
name: Magnier, Eugene
name: Metcalfe, Nigel
name: Wainscoat, Richard
name: Waters, Christopher
name: Kudritzki, Rolf-Peter
name: Burgett, William
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present new spatial models and distance estimates for globular clusters (GC) and dwarf spheroidals (dSphs) orbiting our Galaxy based on RR Lyrae (RRab) stars in the Pan-STARRS1 (PS1) 3$π$ survey. Using the PS1 sample of RRab stars from Sesar et al. (2017) in 16 globular clusters and 5 dwarf galaxies, we fit structural models in $(l,b,D)$ space; for 13 globular clusters and 6 dwarf galaxies, we give only their mean heliocentric distance $D$. We verify the accuracy of the period-luminosity (PL) relations used in Sesar et al. (2017) to constrain the distance to those stars, and compare them to period-luminosity-metallicity (PLZ) relations using metallicities from Carretta et al. (2009). We compare our Sesar et al. (2017) distances to the parallax-based \textit{Gaia} DR2 distance estimates from Bailer-Jones et al. (2018), and find our distances to be consistent and considerably more precise.
Nutritional strategies for reducing enteric methane emission from ruminants
Creators: name: Akhil Kumar Jha, Patel Dipakkumar Ajitbhai, Prashanthini SR, Bhupender
Publisher: name: The Science world a Monthly e magazine
Year: 2024

description: Methane (CH4), a significant greenhouse gas that is mostly produced by ruminants during the enteric fermentation of feed, has a 21-fold greater potential to cause global warming than carbon dioxide. Though the exact role domesticated ruminants play in worldwide methane emissions is a hotly debated topic, anaerobic enteric fermentation of diets is considered to account for approximately 15% of methane emissions overall. Furthermore, methane emissions cause ruminant animals to waste a significant (8–12% of gross energy) portion of feed energy that could otherwise be transformed into metabolizable energy for beneficial uses. As a result, it becomes a responsibility of ruminant nutritionists to reduce methanogenesis for a number of reasons, including the efficient use of feed and, more recently, the impact of global warming. Thus, it is necessary to develop multifaceted strategies for mitigating and adapting to climate change, including genetic improvement strategies (breeding for increased animal productivity, and specific traits related to reduced methane emissions, selection for better feed and nitrogen utilization efficient animals, biotechnological strategies, and nutritional strategies). The most advanced and practically applicable method for lowering methane emissions from livestock is proper nutritional management. The commonly used effective nutritional strategies for reducing enteric methane emission from ruminants include:
Non-uniform continuous dependence on initial data of solutions to the Euler-Poincaré system
Creators: name: Li, Jinlu
name: Dai, Li
name: Zhu, Weipeng
Publisher: name: arXiv
Year: 2018
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this paper, we investigate the continuous dependence on initial data of solutions to the Euler-Poincaré system. By constructing a sequence approximate solutions and calculating the error terms, we show that the data-to-solution map is not uniformly continuous in Sobolev space $H^s(\mathbb{R}^d)$ for $s>1+\frac d2$.
description: 10 pages. arXiv admin note: text overlap with arXiv:1505.00086 by other authors
title: Implementierung von Videokonsultationen in Justizvollzugsanstalten im Rahmen eines telemedizinischen Modellprojekts in Baden-Württemberg – qualitative Ergebnisse der begleitenden Prozessevaluation
Creators: name: Colombo, Miriam
name: Koch, Roland
name: Joos, Stefanie
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Telemedizin gewinnt in vielen medizinischen Fachbereichen an Bedeutung und bietet besonders für vulnerable Gruppen, wie zum Beispiel Patienten/Patientinnen in Justizvollzugsanstalten (JVA), Chancen auf eine verbesserte medizinische Versorgung. Seit Aufhebung des Fernbehandlungsverbots[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
title: Implementierung existierender Behandlungsprotokolle zur strukturierten Versorgung von Patienten mit chronischen Erkrankungen in der Primärversorgung
Creators: name: Glehr, Reingard
name: Semlitsch, Thomas
name: Burgmann, Sarah
name: Korsatko, Stefan
name: Posch, Nicole
name: Spary-Kainz, Ulrike
name: Siebenhofer, Andrea
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Seit der österreichischen Gesundheitsreform 2014 mit dem Ziel der Stärkung der Primärversorgung befindet sich diese im Wandel. Die Weiterentwicklung multiprofessioneller und interdisziplinärer Zusammenarbeit macht eine Etablierung von integrierten Versorgungspfaden mit[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
The Thomas-Fermi approximation for gauge theories
Creators: name: Dixon, D. D.
name: Kaus, P.
name: Wudka, J.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: An effective field approximation, similar to the atomic Thomas-Fermi approach, is proposed for studying non-Abelian gauge theories which includes finite-volume effects. As applications of the formalism the equation of state for an SU(2) gauge theory with massless fermions is obtained. The extensions to realistic situations are briefly discussed.
description: 43 pages, 8 figures, plain TeX; requires epsf and phyzzx
Non-data-aided SNR Estimation for QPSK Modulation in AWGN Channel
Creators: name: Salman, Tara
name: Badawy, Ahmed
name: Elfouly, Tarek M.
name: Khattab, Tamer
name: Mohamed, Amr
Publisher: name: arXiv
Year: 2018
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Signal-to-noise ratio (SNR) estimation is an important parameter that is required in any receiver or communication systems. It can be computed either by a pilot signal data-aided approach in which the transmitted signal would be known to the receiver, or without any knowledge of the transmitted signal, which is a non-data-aided (NDA) estimation approach. In this paper, a NDA SNR estimation algorithm for QPSK signal is proposed. The proposed algorithm modifies the existing Signal- to-Variation Ratio (SVR) SNR estimation algorithm in the aim to reduce its bias and mean square error in case of negative SNR values at low number of samples of it. We first present the existing SVR algorithm and then show the mathematical derivation of the new NDA algorithm. In addition, we compare our algorithm to two baselines estimation methods, namely the M2M4 and SVR algorithms, using different test cases. Those test cases include low SNR values, extremely high SNR values and low number of samples. Results showed that our algorithm had a better performance compared to second and fourth moment estimation (M2M4) and original SVR algorithms in terms of normalized mean square error (NMSE) and bias estimation while keeping almost the same complexity as the original algorithms
description: 2014 IEEE 10th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob)
Thermal Renormalization Group-Equations and the Phase-Transition of Scalar O(N)-Theories
Creators: name: Bergerhoff, Bastian
name: Reingruber, Juergen
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Condensed Matter (cond-mat)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We discuss the formulation of "thermal renormalization group-equations" and their application to the finite temperature phase-transition of scalar O(N)-theories. Thermal renormalization group-equations allow for a computation of both the universal and the non-universal aspects of the critical behavior directly in terms of the zero-temperature physical couplings. They provide a nonperturbative method for a computation of quantities like real-time correlation functions in a thermal environment, where in many situations straightforward perturbation theory fails due to the bad infrared-behavior of the thermal fluctuations. We present results for the critical temperature, critical exponents and amplitudes as well as the scaling equation of state for self-interacting scalar theories.
description: 32 pages with 10 figures and 4 tables included, latex2e
title: Planung und Umsetzung einer komplexen Intervention im Rahmen des Innovationsfonds: Das DEMAND-Projekt
Creators: name: Herrmann, Tobias
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die steigende Inanspruchnahme von Notaufnahmen in Krankenhäusern hat große öffentliche und gesundheitspolitische Aufmerksamkeit erfahren. Dabei wurde v.a. die Überbeanspruchung der Notfallressourcen von Krankenhäusern durch Patienten mit nicht dringlichem Beratungs-[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Additional file 1 of Transcriptomic analysis of paternal behaviors in prairie voles
Creators: name: Duclot, Florian
name: Liu, Yan
name: Saland, Samantha K.
name: Wang, Zuoxin
name: Kabbaj, Mohamed
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Time spent in each behavior during the parental behavior test. The total duration across the entire test session is depicted for each animal for the autogrooming, carry, huddling, licking & grooming, locomotion, nest building, and sniffing behaviors; each data point thus represents a distinct animal. The horizontal line in the shaded violin represents the 50% quantile of the density estimate.
Vacuum effective actions and mass-dependent renormalization in curved space
Creators: name: Franchino-Viñas, Sebastián A.
name: Netto, Tibério de Paula
name: Zanusso, Omar
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We review past and present results on the non-local form-factors of the effective action of semiclassical gravity in two and four dimensions computed by means of a covariant expansion of the heat kernel up to the second order in the curvatures. We discuss the importance of these form-factors in the construction of mass-dependent beta functions for the Newton's constant and the other gravitational couplings.
description: 26 pages, review prepared for the special issue of Universe collecting the contributions for the workshop "Quantum Fields - from Fundamental Concepts to Phenomenological Questions" (Mainz 26-28 September 2018), covers the results of 1803.06948 and 1812.00460
Additional file 3: of Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration
Creators: name: Aguareles, José
name: Paraíso-Luna, Juan
name: Palomares, Belén
name: Bajo-Grañeras, Raquel
name: Navarrete, Carmen
name: Ruiz-Calvo, Andrea
name: García-Rincón, Daniel
name: García-Taboada, Elena
name: Guzmán, Manuel
name: Muñoz, Eduardo
name: Galve-Roperh, Ismael
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Hematology
subject: 60506 Virology

description: hERG Channel Inhibition (IC50 Determination). The experiments were performed on an IonWorks™ HT instrument (Molecular Devices Corporation), which automatically performs electrophysiology measurements in 48 single cells simultaneously in a specialized 384-well plate (PatchPlate™). The cells used were Chinese hamster ovary (CHO) cells stably transfected with hERG (cell-line obtained from Cytomyx, UK). A single-cell suspension was prepared in extracellular solution (Dulbecco’s phosphate buffered saline with calcium and magnesium pH 7–7.2) and aliquots added to each well of a PatchPlate™. Cells were positioned over a small hole at the bottom of each well by applying a vacuum beneath the plate to form an electrical seal. The resistance of each seal was measured via a common ground-electrode in the intracellular compartment and individual electrodes placed into each of the upper wells. Electrical access to the cell was achieved by circulating a perforating agent, amphotericin, underneath the PatchPlate™ and then measuring the pre-compound hERG current. An electrode is positioned in the extracellular compartment and a holding potential of − 80 mV applied for 15 s. The hERG channels were then activated by applying a depolarizing step to + 40 mV for 5 s and then clamped at − 50 mV for 4 s to elicit the hERG tail current, before returning to − 80 mV for 0.3 s. VCE-003.2 were added to the upper wells of the PatchPlate™. Solutions were prepared by diluting 10 mM DMSO solutions of the test compound into extracellular buffer such that the final concentrations tested are 0.008, 0.04, 0.2, 1, 5 and 25 μM (final DMSO concentration 0.25%). Quinidine, an established hERG inhibitor, was included as a positive control and buffer containing 0.25% DMSO was included as a negative control. Post-compound currents were then expressed as a percentage of pre-compound currents and plotted against concentration for each compound. Where concentration-dependent inhibition is observed, the data are fitted and IC50 values were calculated. (PDF 322 kb)
Additional file 10: of Genome sequencing of rice subspecies and genetic analysis of recombinant lines reveals regional yield- and quality-associated loci
Creators: name: Li, Xiukun
name: Wu, Lian
name: Wang, Jiahong
name: Sun, Jian
name: Xia, Xiuhong
name: Geng, Xin
name: Wang, Xuhong
name: Xu, Zhengjin
name: Xu, Quan
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S5. Candidate gene prediction of grain shape regulate locus on chromosome 12. (PDF 23Â kb)
title: Von der Entwicklung bis zur modellhaften Implementierung eines Konzeptes zum Entlassmanagement – ein Ergebnistransfer am Beispiel der Innovationsfondsprojekte EMSE und USER
Creators: name: Kleine-Budde, Katja
name: Pollmann, Thorsten
name: Blum, Karl
name: Finger, Benjamin
name: Gohmann, Philipp
name: Rogalski, Wolfgang
name: Behrendt, Susanne
name: Broge, Björn
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Projekte EMSE und USER beschäftigen sich mit der Entwicklung und Umsetzung eines neuen Konzepts im Bereich des stationären Entlassmanagements (EM). Ziel ist es, Krankenkassen stärker in den Prozess des EM zu integrieren und die Nutzbarkeit von Routinedaten der Krankenkassen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Superconformal Mechanics and the Super Virasoro Algebra
Creators: name: Marcus, Alon
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider N=1,2 superconformal mechanics in 0+1 dimensions and show that if the Hamiltonian is invertible the superconformal generators can be used to construct half of the super Virasoro algebra. The full algebra can be derived if the special conformal generator is also invertible. The generators are quantized and a general prescription is given for the construction of the N=1 algebra independently of the specific details of the superconformal mechanics provided that in addition its quadratic Casimir operator vanishes.
description: Latex, 12 pages, references added, a minor correction
Minimum variance hedging: Levels versus first differences
Creators: name: Prehn, Sören
name: Prehn, Sören
Publisher: name: Unknown
Year: 2021
Subjects: Agricultural Finance
Research Methods/ Statistical Methods

description: Nowadays it is widely accepted to estimate minimum variance hedge ratio regressions in first differences. There are both statistical and economic reasons for a first difference approach. However, no study has ever analyzed whether the first difference approach is also consistent with the theory of minimum variance hedging. In this paper we show, on the basis of a simulation study, that the first difference model with intercept does not provide hedge ratio estimates that are in line with the theory of minimum variance hedging. Only a linear regression model in levels provides theoretically consistent results.
Additional file 3: of RhoTermPredict: an algorithm for predicting Rho-dependent transcription terminators based on Escherichia coli, Bacillus subtilis and Salmonella enterica databases
Creators: name: Salvo, Marco Di
name: Puccio, Simone
name: Peano, Clelia
name: Lacour, Stephan
name: Alifano, Pietro
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Figure S1. Correlation analysis between RNAseq read value ratios and C/G content of putative RUT site of validated genome-wide predictions. (DOCX 296 kb)
Training Future Engineers to Be Ghostbusters: Hunting for the Spectral Environmental Radioactivity
Creators: name: Albéri, Matteo
name: Baldoncini, Marica
name: Bottardi, Carlo
name: Chiarelli, Enrico
name: Landsberger, Sheldon
name: Raptis, Kassandra Giulia Cristina
name: Serafini, Andrea
name: Strati, Virginia
name: Mantovani, Fabio
Publisher: name: arXiv
Year: 2019
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: Although environmental radioactivity is all around us, the collective public imagination often associates a negative feeling to this natural phenomenon. To increase the familiarity with this phenomenon we have designed, implemented, and tested an interdisciplinary educational activity for pre-collegiate students in which nuclear engineering and computer science are ancillary to the comprehension of basic physics concepts. Teaching and training experiences are performed by using a 4" x 4" NaI(Tl) detector for in-situ and laboratory γ-ray spectroscopy measurements. Students are asked to directly assemble the experimental setup and to manage the data-taking with a dedicated Android app, which exploits a client-server system that is based on the Bluetooth communication protocol. The acquired γ-ray spectra and the experimental results are analyzed using a multiple-platform software environment and they are finally shared on an open access Web-GIS service. These all-round activities combining theoretical background, hands-on setup operations, data analysis, and critical synthesis of the results were demonstrated to be effective in increasing students' awareness in quantitatively investigating environmental radioactivity. Supporting information to the basic physics concepts provided in this article can be found at http://www.fe.infn.it/radioactivity/educational.
title: CHIMPS-NET – Kinder und Jugendliche mit psychisch kranken und suchtkranken Eltern – children of mentally ill parents network
Creators: name: Wiegand-Grefe, Silke
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Kinder psychisch kranker Eltern haben ein mehrfach erhöhtes Erkrankungsrisiko für eine eigene psychische Erkrankung. Einige dieser Kinder können trotz der Belastung symptomatisch unauffällig und oftmals sehr angepasst und in hohem Maße funktionierend sein. Bei ca. 50 Prozent[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Incentivising Biodiversity Net Gain with an Offset Market
Creators: name: Simpson, Katherine
name: Hanley, Nick
name: Armsworth, Paul
name: De Vries, Frans
name: Dallimer, Martin
name: Simpson, Katherine
name: Hanley, Nick
name: Armsworth, Paul
name: De Vries, Frans
name: Dallimer, Martin
Publisher: name: Unknown
Year: 2021
Subjects: Land Economics/Use
Environmental Economics and Policy

description: Most programmes which incentivise the supply of public goods such as biodiversity conservation on private land in Europe are financed through the public purse. However, new ideas for how to fund biodiversity conservation are urgently needed, given recent reviews of the poor state of global biodiversity. In this paper, we investigate the use of private funding for biodiversity conservation through an offset market. The environmental objective is to increase some measure of biodiversity in a region (“net gain”) despite the loss of land for new housing. Farmers create biodiversity credits by changing their land management, then sell these credits to housebuilders who are required to more-than offset the impacts of new house building on a specific indicator of biodiversity. Combining an economic model of market operation with an ecological model linking land management to bird populations, we examine the operation, costs and biodiversity impacts of such a (hypothetical) market as the target level of net gain is increased. A general result is established for the impacts on price and quantity in the offset market as the net gain target is make more ambitious. For a case study site in Scotland, we find that as the net gain target is increased, the number of offsets traded in equilibrium falls, as does the market clearing offset price. Changes in the spatial pattern of gains and losses in our biodiversity index also occur as the net gain target is raised.
Magnetic stress as a driving force of structural distortions: the case of CrN
Creators: name: Filippetti, Alessio
name: Hill, Nicola A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We show that the observed transition from rocksalt to orthorhombic P$_{nma}$ symmetry in CrN can be understood in terms of stress anisotropy. Using local spin density functional theory, we find that the imbalance between stress stored in spin-paired and spin-unpaired Cr nearest neighbors causes the rocksalt structure to be unstable against distortions and justifies the observed antiferromagnetic ordering. This stress has a purely magnetic origin, and may be important in any system where the coupling between spin ordering and structure is strong.
description: 4 pages (two columns) 4 figures
Recurrent Neural Networks for P300-based BCI
Creators: name: Tal, Ori
name: Friedman, Doron
Publisher: name: arXiv
Year: 2019
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: P300-based spellers are one of the main methods for EEG-based brain-computer interface, and the detection of the P300 target event with high accuracy is an important prerequisite. The rapid serial visual presentation (RSVP) protocol is of high interest because it can be used by patients who have lost control over their eyes. In this study we wish to explore the suitability of recurrent neural networks (RNNs) as a machine learning method for identifying the P300 signal in RSVP data. We systematically compare RNN with alternative methods such as linear discriminant analysis (LDA) and convolutional neural network (CNN). Our results indicate that LDA performs as well as the neural network models or better on single subject data, but a network combining CNN and RNN has advantages when transferring learning among subejcts, and is significantly more resilient to temporal noise than other methods.
title: Elterliche Akzeptanz der Pneumokokken-Impfung – Entwicklung und Erprobung eines Fragebogens
Creators: name: Buchholz, Maresa
name: Biedenweg, Bianca
name: Schiffner-Rohe, Julia
name: Laurenz, Maren
name: Kohlmann, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Impfungen stellen auch heute eine der erfolgreichsten Präventionsstrategien dar. Aktuelle Impfraten des Robert-Koch-Instituts zeigen jedoch, dass im Vergleich zu weiteren Impfungen im Kindesalter die Teilnahmebereitschaft an der Pneumokokken-Impfung geringer ausfällt. Bislang [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Begonia vinagrera var. pomecensis Jara-Muñoz & Richardson & Zabala-Rivera 2021, var. nov.
Creators: name: Jara-Muñoz, Orlando Adolfo
name: Richardson, James E.
name: Zabala-Rivera, Juan Carlos
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Cucurbitales
Begoniaceae
Begonia
Begonia vinagrera
Begonia vinagrera var. pomecensis jara & zabala-Rivera

description: Begonia vinagrera var. pomecensis  Jara & Zabala-Rivera, var. nov. Figs. 9 & 10
 Type:— COLOMBIA. Boyacá: Municipio de Moniquirá, vereda Alto Colorado, Km 24, via de Arcabuco-Moniquirá, costado sur-occidental, 5°48′51.07″N, 73°29′52,78″W, 2375 m, J. C. Zabala-Rivera, W. Bravo-P. & Z. López-R. 2696 (holotype ANDES!; isotypes COL!, UPTC!).
 Diagnosis:— Begonia vinagrera var. pomecensis differs from the type variety by its larger stipules (10.2–22.9 × 8.5– 11.7 vs. 6.6–7.3 × 3.6–5.6 mm), its longer peduncle (5.4–8.3 (-14.3) vs. 3.1−4.6 cm long), and deciduous bracts (vs. sub-persistent).
 Description:— Stipules early deciduous, oblong or obovate, 10.2–22.9 × 8.5–11.7 mm, apex cuspidate, reddishgreen or reddish-hyaline, glabrous; lamina of the leaf oblong to oblong-lanceolate, apex acuminate. Inflorescence bisexual; peduncle to 5.4–8.3 (14.3) cm long, bracts early deciduous, 4.4–9.4 × 2.6–6.1 mm, reddish-hyaline or reddish-green, apex cuspidate. staminate flowers: pedicels 1.7–4.2 mm long; tepals, outer 2 white, ovate, inner 2 oblong-lanceolate, apex short acuminate. Pistillate flowers: tepals white to reddish-white, subequal, 12.7–18.9 × 7.9– 11.6 mm, apex rounded to short acuminate.
 Etymology:—The name refers to the locality where this variety grows, the narrow valley of the Pomeca River.
 Distribution and habitat:—Only known from the valley of the Pomeca River, most of collections made from the roadsides along the route that connects the cities of Tunja (Boyacá) and Barbosa (Santander).
 Additional specimens examined:— COLOMBIA. Boyacá: municipio de Arcabuco, 5 Km adelante en la carretera a Moniquirá, 18 May 1968, 2375 m, L . Uribe 6095 (COL); Vereda Colorado Alto, Km 22, via Arcabuco-Moniquira, costado sur occidental, 2375 m, 17 June 2015, J . C. Zabala-Rivera, W. Bravo-P 2697 & Z. López-R. (ANDES); Vereda Colorado Alto, Km 20, via Arcabuco-Moniquira, costado sur occidental, 2375 m, 17 June 2015, J . C. Zabala-Rivera, W. Bravo-P & Z. López-R. 2698 (ANDES).
description: Published as part of Jara-Muñoz, Orlando Adolfo, Richardson, James E. & Zabala-Rivera, Juan Carlos, 2021, Five new species and three new varieties of Begonia section Casparya endemic to Colombia, pp. 258-280 in Phytotaxa 525 (4) on pages 276-278, DOI: 10.11646/phytotaxa.525.4.2, http://zenodo.org/record/5723135
MOESM1 of Understanding the interplay between social and spatial behaviour
Creators: name: Alessandretti, Laura
name: Lehmann, Sune
name: Baronchelli, Andrea
Publisher: name: figshare
Year: 2018
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary information. (PDF 455 kB)
On the price effect of a right-of-first-refusal in farmland auctions
Creators: name: Isenhardt, Lars
name: Seifert, Stefan
name: Huettel, Silke
name: Isenhardt, Lars
name: Seifert, Stefan
name: Huettel, Silke
Publisher: name: Unknown
Year: 2021
Subjects: Land Economics/Use
Farm Management

description: Current European Union legislation offers public authorities to grant a right of first refusal (RFR) in farmland auctions with public tenders in favour of the current tenant. That is, tenants can purchase the auctioned lot by matching the highest bid. Granting this right secures tenants to buy the land they use; however, it may deter other potential buyers’ auction participation and incentivise bidders to adjust their strategies. A RFR for tenants is thus hypothesised to decrease the number of bidders and lower sales prices. Empirical evidence seems lacking thus far; in this paper, we target at closing this gap by analysing a tenants’ RFR effect on the number of bidders and winning bids in first-price privatization auctions in eastern Germany. Using around 4,000 land auction results in one German Federal State over 2007-2018 by two agencies that differ in granting the RFR to tenants, we combine non-parametric nearest neighbour matching based on the Mahalanobis distance with parametric post-matching regressions. Our results indicate that the RFR reduces competition by an average 8.3% bidders per auction and lowers the prices paid in land auctions by 16.7 %.
title: Konstrukttheoretische Auseinandersetzung mit der sozialen Partizipation von Jugendlichen zur Entwicklung eines Partizipationsmessinstruments für die (Re-)Habilitation – internationale Perspektiven
Creators: name: Fink, Astrid
name: Martin, Olaf
name: Hoffmann, Laura
name: Spreer, Markus
name: Gebhard, Britta
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Für Jugendliche ist die Partizipation (Teilhabe) in verschiedensten Lebenssituationen wichtiger Bestandteil ihrer Entwicklung, da sie grundlegend und prägend den sozialen Erfahrungsbereich, die sozial-emotionale Entwicklung und Dimensionen der Kompetenzerfahrung beeinflussen. [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 18. Deutscher Kongress für Versorgungsforschung (DKVF)
Amplitudes at Infinity
Creators: name: Bourjaily, Jacob L.
name: Herrmann, Enrico
name: Trnka, Jaroslav
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the asymptotically large loop-momentum behavior of multi-loop amplitudes in maximally supersymmetric quantum field theories in four dimensions. We check residue-theorem identities among color-dressed leading singularities in $\mathcal{N}=4$ supersymmetric Yang-Mills theory to demonstrate the absence of poles at infinity of all MHV amplitudes through three loops. Considering the same test for $\mathcal{N}=8$ supergravity leads us to discover that this theory does support non-vanishing residues at infinity starting at two loops, and the degree of these poles grow arbitrarily with multiplicity. This causes a tension between simultaneously manifesting ultraviolet finiteness---which would be automatic in a representation obtained by color-kinematic duality---and gauge invariance---which would follow from unitarity-based methods.
description: 4+1+1 pages; 15 figures; details provided in ancillary Mathematica files
Additional file 1: of Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration
Creators: name: Aguareles, José
name: Paraíso-Luna, Juan
name: Palomares, Belén
name: Bajo-Grañeras, Raquel
name: Navarrete, Carmen
name: Ruiz-Calvo, Andrea
name: García-Rincón, Daniel
name: García-Taboada, Elena
name: Guzmán, Manuel
name: Muñoz, Eduardo
name: Galve-Roperh, Ismael
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Inorganic Chemistry

description: Microsomal Metabolic Stability. Pooled human liver microsomes (final protein concentration 0.5 mg/mL), 0.1 M phosphate buffer pH 7.4 and the test compounds (VCE-003.2, CBG, verapamil and dextromethorphan) were pre-incubated at 37 °C prior to the addition of 1 mM NADPH to initiate the reaction. The final incubation volume was 25 μL. Each compound was incubated for 0, 5, 15, 30 and 45 min. The control (minus NADPH) was incubated for 45 min only. The reactions were stopped by the addition of 50 μL methanol containing internal standard at the appropriate time points. The incubation plates were centrifuged at 2500 rpm for 20 min at 4 °C to precipitate the protein. Following protein precipitation, the sample supernatants were analyzed using LC-MS/MS. From a plot of ln peak area ratio (compound peak area/internal standard peak area) against time, the gradient of the line was determined. Subsequently, half-life and intrinsic clearance was calculated using the equations below: Elimination rate constant (k) = (− gradient). Half-life (t1/2) (min) = 0.693 k $$ \frac{0.693}{k} $$ . Intrinsic Clearance (CLint) (μL/min/mg protein) = V × 0.693 t 1 / 2 $$ \frac{V\times 0.693}{t_{1/2}} $$ . where V=Incubation volume mL/mg microsomal protein. (PDF 373 kb)