cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
In vivo efficacy of novel antibacterial and immunomodulatory peptides
Creators: name: Waldbrook, Matthew George
Publisher: name: University of British Columbia
Year: 2008

description: Despite the success of modern medicine in treating infections, infectious diseases remain a major source of morbidity and mortality worldwide. The evolution of antibiotic resistant strains of bacteria means that new innovations in therapeutics must be pursued to combat this emerging threat. A novel approach is to utilize the anti-infective properties of endogenous host defense peptides by creating smaller synthetic peptides with enhanced protective activities. Some of these peptides directly kill bacteria and many display varied immunomodulatory activities, enhancing the host innate immune response to more effectively clear an infection. Here I examined the efficacy of several synthetic peptides in a murine model of invasive bacterial infection, induced by the Gram positive bacterium Staphylococcus aureus. Several peptides were able to significantly reduce peritoneal bacterial load in vivo by up to 4-logs relative to the controls, either through direct antibacterial killing or immunomodulatory activity. The latter class was studied in more detail; in particular, the peptides IDR-1 and 1002 displayed significant immunomodulatory effects in vivo. Both peptides were able to significantly induce the proinflammatory chemokines MCP-1, RANTES and KC, as well as increased recruitment of neutrophils and monocytes to the site of infection. These effects were not dependent on live bacteria, as heat inactivated S. aureus was also able to induce chemokines and cell migration. Mice that had been depleted of macrophages did not respond to peptide treatment, indicating that macrophages are an important effector cells through which immunomodulatory peptides counter infections. These results suggest that synthetic peptides have the potential to become a viable treatment option for bacterial infections.
Exobasidiomycetes
Creators: name: Calabon, Mark S.
name: Jones, E. B. Gareth
name: Pang, Ka-Lai
name: Abdel-Wahab, Mohamed A.
name: Jin, Jing
name: Devadatha, Bandarupalli
name: Sadaba, Resurreccion B.
name: Apurillo, Carlo Chris
name: Hyde, Kevin D.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Exobasidiomycetes

description: 2.2.2 Golubeviales (Exobasidiomycetes, Basidiomycota)
The order was introduced for the genus Golubeva with G. pallescens as the type species (Wang et al. 2015). In a multigene phylogeny and taxonomic revision of yeasts in the Ustilaginomycotina, two species in the genus Tilletiopsis (T. albescens, T. pallescens) grouped separately from the Tilletiopsis clade and these were referred to new genera, Robbauera and Golubeva, respectively. These genera served as new families and orders in the Ustilaginomycotina. Golubeva is the type genus for the Golubeviaceae, Golubeviales (Wang et al. 2015), a new name for the checklist.
description: Published as part of Calabon, Mark S., Jones, E. B. Gareth, Pang, Ka-Lai, Abdel-Wahab, Mohamed A., Jin, Jing, Devadatha, Bandarupalli, Sadaba, Resurreccion B., Apurillo, Carlo Chris & Hyde, Kevin D., 2023, Updates on the classification and numbers of marine fungi, pp. 213-238 in Botanica Marina (Warsaw, Poland) (Warsaw, Poland) 66 (4) on page 214, DOI: 10.1515/bot-2023-0032, http://zenodo.org/record/11000251
Lobulomycetales
Creators: name: Calabon, Mark S.
name: Jones, E. B. Gareth
name: Pang, Ka-Lai
name: Abdel-Wahab, Mohamed A.
name: Jin, Jing
name: Devadatha, Bandarupalli
name: Sadaba, Resurreccion B.
name: Apurillo, Carlo Chris
name: Hyde, Kevin D.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Chytridiomycota
Chytridiomycetes
Lobulomycetales

description: 2.2.3 Lobulomycetales (Lobulomycetes, Chytridiomycota)
Lobulomycetales was introduced by Simmons et al. (2009) based on genetic analyses, morphology, and ultrastructural data, with Lobulomyces (Lobulomycetaceae) and L. angularis as the type genus and species, respectively. Features of the order are a polycentric or monocentric thallus, multiple rhizoidal axes, spherical motile zoospores with or without a flagellar plug, ultrastructural details of the kinestosome, growing on chitin in soil and freshwater/seawater. Two families are assigned to the order Lobulomycetaceae and (Alogomycetaceae). Alogomyces tanneri (Alogomycetaceae) is known from marine habitats; based on environmental DNA samples from the deep ocean (Le Calvez et al. 2009; Yan et al. 2020).
description: Published as part of Calabon, Mark S., Jones, E. B. Gareth, Pang, Ka-Lai, Abdel-Wahab, Mohamed A., Jin, Jing, Devadatha, Bandarupalli, Sadaba, Resurreccion B., Apurillo, Carlo Chris & Hyde, Kevin D., 2023, Updates on the classification and numbers of marine fungi, pp. 213-238 in Botanica Marina (Warsaw, Poland) (Warsaw, Poland) 66 (4) on page 214, DOI: 10.1515/bot-2023-0032, http://zenodo.org/record/11000251
Additional file 2: Figure S1. of Single-cell analysis of long non-coding RNAs in the developing human neocortex
Creators: name: Siyuan Liu
name: Nowakowski, Tomasz
name: Pollen, Alex
name: Lui, Jan
name: Horlbeck, Max
name: Attenello, Frank
name: He, Daniel
name: Weissman, Jonathan
name: Kriegstein, Arnold
name: Diaz, Aaron
name: Lim, Daniel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Computational pipeline of lncRNA identification. A ROC analysis of coverage thresholds required to fully annotate known transcripts in poly(A) and total RNA-seq data. Coverage thresholds were selected for which false positive rates were 0.05, corresponding to the optimal balance of false positive and true positive rates. B Venn diagrams of novel transcripts classified as protein coding by CPC, CPAT, and Pfam search. The union of the transcripts were annotated TUCPs. C Number of novel poly(A) lncRNAs expressed in the Full (red) and Stringent (blue) references compared to Cabili et al. 2011, Ensembl 75/GENCODE 19, Hangauer et al. [7], and Iyer et al. [6] (MiTranscriptome). D Maximum expression levels of transcripts described in the Full (white) and Stringent (gray) references derived total RNA-seq across all samples. TPM, Transcripts per Million. E Numbers of expressed mRNAs, lncRNAs, and TUCPs during neocortex development in bulk tissues, according to total RNA-seq libraries. F Top gene ontology terms for differentially expressed mRNAs (left) and mRNA neighbors of lncRNAs/TUCPs (right). (PDF 165 kb)
Monoblastiales
Creators: name: Calabon, Mark S.
name: Jones, E. B. Gareth
name: Pang, Ka-Lai
name: Abdel-Wahab, Mohamed A.
name: Jin, Jing
name: Devadatha, Bandarupalli
name: Sadaba, Resurreccion B.
name: Apurillo, Carlo Chris
name: Hyde, Kevin D.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Dothideomycetes
Monoblastiales

description: 2.2.4 Monoblastiales (Dothideomycetes, Ascomycota)
The genus Heleiosa was introduced by Kohlmeyer et al. (1996), for the type species H. barbatula, growing on leaves of Juncus roemerianus in salt marshes, and referred to the Dothideomycetes incertae sedis. Subsequently it was attributed to Monoblastiaceae (Monoblastiales) which includes both lichenized and non-lichenized ascomycetes (Wijayawardene et al. 2022). Monoblastiales was introduced by Hyde et al. (2013), and H. barbatula was referred to this order by Hongsanan et al. (2020b).
description: Published as part of Calabon, Mark S., Jones, E. B. Gareth, Pang, Ka-Lai, Abdel-Wahab, Mohamed A., Jin, Jing, Devadatha, Bandarupalli, Sadaba, Resurreccion B., Apurillo, Carlo Chris & Hyde, Kevin D., 2023, Updates on the classification and numbers of marine fungi, pp. 213-238 in Botanica Marina (Warsaw, Poland) (Warsaw, Poland) 66 (4) on page 215, DOI: 10.1515/bot-2023-0032, http://zenodo.org/record/11000251
Mycotretus scalaris Lacordaire 1842
Creators: name: Pecci-Maddalena, Italo Salvatore de Castro
name: Lopes-Andrade, Cristiano
name: Skelley, Paul
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Erotylidae
Mycotretus
Mycotretus scalaris

description: 204. Mycotretus scalaris Lacordaire, 1842
Mycotretus scalaris Lacordaire, 1842: 168. Type locality: “ Colombie ”.
Mycotretus scalaris – Crotch 1876: 440. — Gemminger & Harold 1876: 3695. — Kuhnt 1909: 71; 1911: 53. — Blackwelder 1945: 467. — Alvarenga 1994: 35.
Primary type
Lectotype, here designated (Fig. 36D)
COLOMBIA • “Ex-Musaeo, Mniszech [printed] \ Type [handwritten] \ Scalaris Lac [handwritten] \ Colombie [handwritten] \ LECTOTYPE [printed] Mycotretus scalaris Lacordaire, 1842 [red label, handwritten]”; MNHN.
Distribution
Unknown locality in Colombia.
description: Published as part of Pecci-Maddalena, Italo Salvatore de Castro, Lopes-Andrade, Cristiano & Skelley, Paul, 2023, Catalogue of Mycotretus Lacordaire, 1842 (Coleoptera: Erotylidae: Tritomini): an annotated, illustrated and historical approach, pp. 1-182 in European Journal of Taxonomy 876 (1) on page 156, DOI: 10.5852/ejt.2023.876.2149, http://zenodo.org/record/8095647
Additional file 16: Figure S9. of Single-cell analysis of long non-coding RNAs in the developing human neocortex
Creators: name: Siyuan Liu
name: Nowakowski, Tomasz
name: Pollen, Alex
name: Lui, Jan
name: Horlbeck, Max
name: Attenello, Frank
name: He, Daniel
name: Weissman, Jonathan
name: Kriegstein, Arnold
name: Diaz, Aaron
name: Lim, Daniel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Gene co-expression analysis of cell type-specific lncRNAs in single cells. A Matrix of Pearson correlation coefficients between cell type-specific lncRNAs and the top 10Â % most correlated or anticorrelated mRNAs across single cells. B Gene ontology terms for gene clusters identified in the correlation matrix. Cluster nodes are labeled with red circles. Header bar colors for lncRNAs: red, endothelial; blue, radial glia; green, dividing radial glia; purple, intermediate progenitor cell; orange, newborn neurons; yellow, maturing neurons; brown, interneurons. (PDF 211 kb)
Additional file 2: Figure S2. of RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis
Creators: name: Gan, Wen-Juan
name: Wang, Jing-Ru
name: Zhu, Xiao-Li
name: He, Xiao-Shun
name: Peng-Da Guo
name: Zhang, Shen
name: Li, Xiu-Ming
name: Li, Jian-Ming
name: Wu, Hua
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology

description: Knockdown of RARγ does not affect the expression of Vimentin, N-cadherin and Occludin. qPCR analysis of the vimentin, N-cadherin and occludin expression in RARγ siRNA-transduced MHCC-97H cells. Statistical significance was determined by a two-tailed, unpaired Student's t-test. ns, no significance. (PDF 30 kb)
Additional file 1: Figure S1. of DectICO: an alignment-free supervised metagenomic classification method based on feature extraction and dynamic selection
Creators: name: Ding, Xiao
name: Fudong Cheng
name: Changchang Cao
name: Sun, Xiao
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Comparisons of classification performance between DectICO and the unsupervised alignment-free metagenomic clustering methods. Table S2. The information of the three collections of metagenomes. Table S3. The sizes of the training and testing sets for three collections of metagenomes used in our stability test and generality test. Figure S2. Comparisons of classification performances between DectICO and the non-dynamic feature-selection-based method on the T2D dataset. Figure S3. Comparisons of classification performances between DectICO and RSVM that based on the ICO on the asthma and T2D datasets. Table S4. Comparisons of the stability (from stability test) and generality (from generality test) between DectICO and the RSVM that with the ICO on asthma dataset. Table S5. Comparisons of the stability (from stability test) and generality (from generality test) between DectICO and the RSVM that with the ICO on T2D dataset. Table S6. The runtime of calculation for the feature vectors of ICO based on three kinds of metagenomic samples and 1 Mbp contig. Table S7. The consumed RAM of calculation for the feature vectors of ICO based on three kinds of metagenomic samples. Table S8. The runtime of classification process with varying rounds of feature selection and different numbers of samples in training set on the T2D metagenomes. Table S9. The consumed RAM of classification process with varying rounds of feature selection and different numbers of samples in training set on the T2D metagenomes. Table S10. The ICO vector dimension for different length oligonucleotides. (DOCX 76 kb)
Additional file 15: Figure S8. of Single-cell analysis of long non-coding RNAs in the developing human neocortex
Creators: name: Siyuan Liu
name: Nowakowski, Tomasz
name: Pollen, Alex
name: Lui, Jan
name: Horlbeck, Max
name: Attenello, Frank
name: He, Daniel
name: Weissman, Jonathan
name: Kriegstein, Arnold
name: Diaz, Aaron
name: Lim, Daniel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Abundant expression of cell type-specific lncRNAs in single cells. A Distributions of expression levels of cell type-specific mRNAs and (B) lncRNAs in single neocortex cells, binned by log2(Normalized Countsâ  +â  1). Heatmap colors represent number of cells in each bin. Genes were ranked by their median expression levels across 276 neocortex single cells. Columns adjacent to gene names represent cell type assignments. C Distributions of maximum log odds ratios for cell type-specific gene expression at 75%ile threshold for each lncRNA (blue) and mRNA (red) at different quantiles of expression. D Cumulative distributions of cell type specificity scores for lncRNAs expressed at various levels in bulk tissues. Endo/red, endothelial; RG/blue, radial glia; DRG/green, dividing radial glia; IPC/purple, intermediate progenitor cell; NN/orange, newborn neurons; MN/yellow, maturing neurons; INTER/brown, interneurons. (PDF 120 kb)
Additional file 1: Figure S1. of RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis
Creators: name: Gan, Wen-Juan
name: Wang, Jing-Ru
name: Zhu, Xiao-Li
name: He, Xiao-Shun
name: Peng-Da Guo
name: Zhang, Shen
name: Li, Xiu-Ming
name: Li, Jian-Ming
name: Wu, Hua
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: The efficiency of RARγ depletion in MHCC-97H. Immunoblotting of RARγ in MHCC-97H cells that stably transfected with shRNA/Control or shRNA/RARγ. (PDF 57 kb)
Muyocopronales
Creators: name: Calabon, Mark S.
name: Jones, E. B. Gareth
name: Pang, Ka-Lai
name: Abdel-Wahab, Mohamed A.
name: Jin, Jing
name: Devadatha, Bandarupalli
name: Sadaba, Resurreccion B.
name: Apurillo, Carlo Chris
name: Hyde, Kevin D.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Dothideomycetes
Muyocopronales

description: 2.2.5 Muyocopronales (Dothideomycetes, Ascomycota)
Muyocopronaceae was invalidly introduced by Luttrell (1951) and later reintroduced by Hyde et al. (2013) while the order Muyocopronales was introduced by Mapook et al. (2016). Ellisiodothis inquinans (Muyocopronaceae) was reported from Spartina alterni fl ora in Buenos Aires, Argentina by Gessner and Kohlmeyer (1976), but there is no further documentation.
description: Published as part of Calabon, Mark S., Jones, E. B. Gareth, Pang, Ka-Lai, Abdel-Wahab, Mohamed A., Jin, Jing, Devadatha, Bandarupalli, Sadaba, Resurreccion B., Apurillo, Carlo Chris & Hyde, Kevin D., 2023, Updates on the classification and numbers of marine fungi, pp. 213-238 in Botanica Marina (Warsaw, Poland) (Warsaw, Poland) 66 (4) on page 215, DOI: 10.1515/bot-2023-0032, http://zenodo.org/record/11000251
Optimal resource management in wireless access networks
Creators: name: Mohsenian-Rad, Amir-Hamed
Publisher: name: University of British Columbia
Year: 2008

description: This thesis presents several simple, robust, and optimal resource management schemes for multihop wireless access networks with the main focus on multi-channel wireless mesh networks (MC WMNs). In this regard, various resource management optimization problems are formulated arid efficient algorithms are proposed to solve each problem. First, we consider the channel as signment problem in MC-WMNs and formulate different resource management problems within the general framework of network utility maximization (NUM). Unlike most of the previously proposed channel assignment schemes, our algorithms can not only assign the orthogonal (i.e., non-overlapped) channels, but also partially overlapped channels. This better utilizes the avail able frequency spectrum as a critical resource in MC-WMNs. Second, we propose two distributed random medium access control (MAC) algorithms to solve a non-convex NUM problem at the MAC layer. The first algorithm is fast, optimal, and robust to message loss and delay. It also only requires a limited message passing among the wireless nodes. Using distributed learning techniques, we then propose another NUM-based MAC algorithm which achieves the optimal performance without frequent message exchange. Third, based on our results on random MAC, we develop a distributed multi-interface multi-channel random access algorithm to solve the NUM problem in MC-WMNs. Different from most of the previous channel assignment schemes in the literature, where channel assignment is intuitively modeled in the form of combinatorial and discrete optimization problems, our scheme is based on formulating a novel continuous optimization model. This makes the analysis and implementation significantly easier. Finally, we consider the problem of pricing and monetary exchange in multi-hop wireless access networks, where each intermediate node receives a payment to compensate for its offered packet forwarding service. In this regard, we propose a market-based wireless access network model with two-fold pricing. It uses relay-pricing to encourage collaboration among the access points. It also uses interference pricing to leverage optimal resource management. In general, this thesis widely benefits from several mathematical techniques as both modeling and solution tools to achieve simple, robust, optimal, and practical resource management strategies for future wireless access networks.
Ditaxiporinae Stach 1935
Creators: name: Vieira, Leandro M.
name: Gordon, Dennis P.
name: Correia, Monica D.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Bryozoa
Gymnolaemata
Cheilostomatida
Catenicellidae

description: Subfamily Ditaxiporinae Stach, 1935
Diagnosis. Colony erect, jointed, comprising sterile internodes that are mostly multizooidal and biserial, rarely unizooidal in part or all of the colony; fertile internodes always multizooidal and biserial. Frontal shield varied; multi-costate, or mostly with vestigial suboral costae so that there is an extensive gymnocyst, typically foraminate; or the gymnocyst reduced owing to expansion of pore-chambers frontally so that most of the shield is effectively cryptocystal. Ovicells likewise variable, ectooecium well-developed, smooth, with a suture or foramina, or ectooecium reduced, exposing extensive granular endooecium. Dorsal surface of zooids smooth or with pore-chambers variably developed. Avicularia typically lateral-oral and mostly with complete cross-bar.
Remarks. Stach (1933, 1934, 1935) subdivided the Catenicellidae into several subfamilies, basing them primarily on the position of the ovicell within the segment. He named five subfamilies — Vittaticellinae Stach, 1933, Scuticellinae Stach, 1934, Catenicellinae Stach, 1935, Cornuticellinae Stach, 1935, and Ditaxiporinae Stach, 1935. Additionally, Cheetham (1963) introduced a new family-rank taxon, Ditaxiporinidae. Gordon & Braga (1994) commented on these arrangements, synonymising some. They regarded biseriality (i.e., multizooidal) as having more fundamental significance within the family than the position of the ovicell (or the morphology of the frontal shield), which they interpret as having differentiated within different lineages later. For these reasons they subsumed the Ditaxiporinidae into the Ditaxiporinae.
description: Published as part of Vieira, Leandro M., Gordon, Dennis P. & Correia, Monica D., 2007, First record of a living ditaxiporine catenicellid in the Atlantic, with a description of Vasignyella ovicellata n. sp. (Bryozoa), pp. 49-58 in Zootaxa 1582 (1) on page 51, DOI: 10.11646/zootaxa.1582.1.5, http://zenodo.org/record/5097621
Additional file 1: of Clinical effectiveness of cell therapies in patients with chronic liver disease and acute-on-chronic liver failure: a systematic review protocol
Creators: name: Nwe Than
name: Tomlinson, Claire
name: Haldar, Debashis
name: King, Andrew
name: Moore, David
name: Newsome, Philip
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: PRISMA-P (Preferred Reporting Items for Systematic review and Meta-Analysis Protocols) 2015 checklist: recommended items to address in a systematic review protocol*. (DOC 82Â kb)
Additional file 2: Table S1. of Comparative proteomic analysis provides novel insight into the interaction between resistant vs susceptible tomato cultivars and TYLCV infection
Creators: name: Huang, Ying
name: Ma, Hong-Yu
name: Huang, Wei
name: Wang, Feng
name: Xu, Zhi-Sheng
name: Ai-Sheng Xiong
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: Ecology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology
subject: 60506 Virology

description: Primers of the selected genes used in the text. (DOC 58 kb)
title: ÐÐµÑÐ¾Ð´Ð¸ÐºÐ° ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð²Ð½Ð¾Ð¹ Ð¼ÐµÐ´Ð¸Ð°ÐºÐ¾Ð¼Ð¿ÐµÑÐµÐ½ÑÐ¸Ð¸ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¿ÑÐµÐ´Ð¼ÐµÑÐ½Ð¾-ÑÐ·ÑÐºÐ¾Ð²Ð¾Ð³Ð¾ Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ (ÑÐµÑ Ð½Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð²ÑÐ·)
title: Ð½Ð°ÑÑÐ½ÑÐ¹ Ð´Ð¾ÐºÐ»Ð°Ð´
titleType: Subtitle
title: Methodology of studentsâ communicative media competence formation on the basis of the content and language integrated learning (technical university)
Creators: name: ÐÑÐ·Ð½ÐµÑÐ¾Ð²Ð°, ÐÐ»ÑÐ³Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: ÐÑÑÐ¾Ð½Ð°Ð²Ð¸Ð³Ð°ÑÐ¸Ñ
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stepik
subject-language integrated learning
communicative media competence
dialog
aviation English

description: Ð Ð°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¸Ñ Ð½Ð°ÑÑÐ½Ð¾Ð³Ð¾ Ð¸ Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð²Ð½Ð¾Ð¹ Ð¼ÐµÐ´Ð¸Ð°ÐºÐ¾Ð¼Ð¿ÐµÑÐµÐ½ÑÐ¸Ð¸. ÐÐ²ÑÐ¾ÑÐ¾Ð¼ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑÑÑ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ Ð¿ÑÐµÐ´Ð¼ÐµÑÐ½Ð¾-ÑÐ·ÑÐºÐ¾Ð²Ð¾Ð³Ð¾ Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð¸ Ð¼ÐµÐ´Ð¸Ð° ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐ¾Ð·Ð´Ð°ÑÑ ÑÐµÐ°Ð»Ð¸Ð·ÑÑÑÐ¸Ðµ ÑÑÐ»Ð¾Ð²Ð¸Ñ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð½ÑÑ Ð¤ÐÐÐ¡ ÐÐ 3++ ÐºÐ¾Ð¼Ð¿ÐµÑÐµÐ½ÑÐ¸Ð¹. Ð Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¿Ð¾ÐºÐ°Ð·Ð°Ð½Ð° Ð¸Ð´ÐµÑ Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¿Ð¾ ÑÐ¸Ð¿Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¼ÐµÐ´Ð¸Ð°ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹, Ð¸Ñ ÑÐ¸Ð½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ð² Ð¾Ð±ÑÑÐµÐ½Ð¸Ð¸ Ð¿Ð¾ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐµ CLIL Ð² ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ð¸ ÐÐÐ. Ð Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð°Ð²ÑÐ¾ÑÑÐºÐ¸Ð¹ Ð­Ð£Ð Â«AVIATION ENGLISHÂ» Ð½Ð° Ð±Ð°Ð·Ðµ Ð­ÐÐ¡ Â«StepikÂ», Ð°Ð²ÑÐ¾ÑÑÐºÐ¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð¿Ð¾ Ð´Ð°Ð½Ð½Ð¾Ð¼Ñ ÐºÑÑÑÑ.
description: The dissertation under consideration is devoted to the question of the scientific and methodological support in the framework of the communicative media competence formation. The use of the CLIL methodology and multimedia technologies creating conditions for the competencies formation established by the Federal State Educational Standard of Higher Education 3++ is shown. The presented concept implements the idea of integrated multimedia technologies implementation, its synergistic action into subject studying by means of CLIL to form Communicative Media Competence (CMC). The study presents the author's e-learning course Â«AVIATION ENGLISHÂ» based on the e-learning platform Â«StepikÂ», and the author's textbook for this course.
Role of podocalyxin in hematopoiesis and cell migration
Creators: name: Tan, Poh Choo
Publisher: name: University of British Columbia
Year: 2008

description: CD34 and its relatives, Podocalyxin and Endoglycan, comprise of a family of surface sialomucins expressed by hematopoietic stem/progenitor cells, and vascular endothelia. Recent data suggest that they serve as either pro- or anti-adhesion molecules depending on their cellular context and their post-translational modifications. We were interested in identifying Podocalyxin ligands and their cellular distribution and understanding the role of these factors in signaling, adhesion and migration. Using both a lambda phage screen assay and mass spectrometry, we identified the Na⁺/H⁺ exchanger regulatory factor-i (NHERF-l) as a selective ligand for Podocalyxin and Endoglycan but not for the closely related CD34. Furthermore, we showed that NHERF-1 is expressed by all, lineage⁻, Sca-1⁺ and c-kit⁺ (LSK) cells, which are known to express Podocalyxin and have long-term repopulating characteristics of hematopoietic stem cells. In addition, upon IL-3 stimulation of a factor dependent cell line (FDC-P 1) these proteins re-localize and co-localize in an asymmetrical pattern. By using a lentiviral based shRNA system to silence Podocalyxin and NHERF- i proteins, we observed that migration across stromal monolayer towards a CXCL12 and SCF gradient is significantly impeded in cells that lack Podocalyxin but not NHERF-1. Following in vitro stimulation with a combination of CXCL12 and SCF we observed that Podocalyxin co-associates with CXCR4. Furthermore, cells lacking Podocalyxin have decreased phospho-AKT, a key signaling molecule downstream of c-kit and CXCR4 receptors. Taken together, our data supports the conclusion that Podocalyxin co-association with CXCR4 modulates downstream signaling to efficiently regulate HSC homing.
Mycotretus sexoculatus subsp. sexoculatus Lacordaire 1842
Creators: name: Pecci-Maddalena, Italo Salvatore de Castro
name: Lopes-Andrade, Cristiano
name: Skelley, Paul
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Erotylidae
Mycotretus
Mycotretus sexoculatus
Mycotretus sexoculatus sexoculatus lacordaire, 1842

description: 206. Mycotretus sexoculatus sexoculatus Lacordaire, 1842
Mycotretus sexoculatus sexoculatus Lacordaire, 1842: 165. Type locality: “ Colombie ”.
Mycotretus sexoculatus sexoculatus – Crotch 1876: 439. — Gemminger & Harold 1876: 3695. — Kuhnt 1909: 74; 1911: 53. — Blackwelder 1945: 467. — Alvarenga 1994: 35. — Skelley 1998b: 15.
Primary type
Lectotype, here designated (Fig. 36F)
COLOMBIA • “TYPE [blue label, printed] \ TYPE. [printed] 6-oculatus R [handwritten] \ Nova Gr [handwritten] \ LECTOTYPE [printed] Mycotretus sexoculatus Lacordaire, 1842 [red label, handwritten]”; UMCZ.
Other specimens examined
BRAZIL • 1 ♀ (dissected); “Coleção M. Alvarenga [printed] \ Homeotipo [printed] \ CORCOVADO, Guanabara BRASIL [printed] XI. 1967 [handwritten], Alvarenga & Seabra [printed] \ Comparado c/ tipo, Mycotretus sexoculatus Lac. 1842 [handwritten] M. Alvarenga det. 1971 [printed]”; MNRJ • 1 ♀ (dissected); “Coleção M. Alvarenga [printed] \ REPRÊSA RIO GRANDE, Guanabara BRASIL [printed] XII. 1977 [handwritten] F.M. Oliveira [printed] \ Mycotretus sexoculatus sexoculatus Lac. 1842 [handwritten] M. Alvarenga det. [printed] 1984 [handwritten]”; MNRJ • 1 ♂ (dissected); “Coleção M.Alvarenga [printed] \ REPRÊSA RIO GRANDE, Guanabara BRASIL [printed] IV. 1966 [handwritten] F.M. Oliveira [printed] \ MALAISE [handwritten] \ mycotretus 020 [handwritten]”; MNRJ.
Distribution
Colombia, Southeast Brazil.
description: Published as part of Pecci-Maddalena, Italo Salvatore de Castro, Lopes-Andrade, Cristiano & Skelley, Paul, 2023, Catalogue of Mycotretus Lacordaire, 1842 (Coleoptera: Erotylidae: Tritomini): an annotated, illustrated and historical approach, pp. 1-182 in European Journal of Taxonomy 876 (1) on pages 157-159, DOI: 10.5852/ejt.2023.876.2149, http://zenodo.org/record/8095647
Vasignyella Gordon 1989
Creators: name: Vieira, Leandro M.
name: Gordon, Dennis P.
name: Correia, Monica D.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Bryozoa
Gymnolaemata
Cheilostomatida
Catenicellidae
Vasignyella

description: Genus Vasignyella Gordon, 1989
Type species. Catenaria otophora Kirkpatrick, 1890, by original designation.
Diagnosis (Amended). Colony erect, comprising branching uniserial chains of unizooidal internodes or with infrequent biserial multizooidal internodes with some zooids ovicellate. Zooids elongate, claviform in uniserial internodes or if located proximally in a multizooidal internode. Frontal shield a gymnocyst with numerous foramina and vestigial costal elements forming the proximal rim of the orifice. Small mural pore-chambers present. Orifice broadly sinusoid; no oral spines. Paired lateral-oral avicularia. Ovicells prominent, ectooecium perforated.
Remarks. Only two species are known so far—the type species and the new species reported here. They occur frequently in associations with other bryozoans. Vasignyella otophora occurs from the low intertidal to 49 m depth in the Indo-Pacific: Indian Ocean, China Sea, Philippines, New Guinea, Rotuma (Harmer 1957), Red Sea (Dumont 1981), Samoa (Gordon 1989), Heron Island, Great Barrier Reef (Ryland & Hayward 1992), and Erakor Island, Vanuatu (Tilbrook et al. 2001). A Miocene fossil from Indonesia has also been attributed to this species (Lagaaij 1968).
description: Published as part of Vieira, Leandro M., Gordon, Dennis P. & Correia, Monica D., 2007, First record of a living ditaxiporine catenicellid in the Atlantic, with a description of Vasignyella ovicellata n. sp. (Bryozoa), pp. 49-58 in Zootaxa 1582 (1) on page 51, DOI: 10.11646/zootaxa.1582.1.5, http://zenodo.org/record/5097621
Additional file 2: Table S2. of A novel quantification method for the total demethylation potential of aquatic sample extracts from Bohai Bay using the EGFP reporter gene
Creators: name: Qian, Yan
name: Xiaoli Wang
name: Zhanlu Lv
name: Guo, Chen
name: Han, Mei
name: Jiabing Wu
name: Yongjian Yang
name: Yishu Yang
name: Jiang, Yan
name: Yongjie Wei
name: Nie, Jing
name: Liang, Bao
name: Jinliang Zhang
name: Xianliang Wang
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The detection limit of TDQ experiment with repetitive tests of 5-AZA-CdR. (PDF 11Â kb)
Mycotretus silaceus Lacordaire 1842
Creators: name: Pecci-Maddalena, Italo Salvatore de Castro
name: Lopes-Andrade, Cristiano
name: Skelley, Paul
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Erotylidae
Mycotretus
Mycotretus silaceus

description: 207. Mycotretus silaceus Lacordaire, 1842
Mycotretus silaceus Lacordaire, 1842: 187 (Fig. 37A). Type locality: “ Brésil ”.
Mycotretus silaceus Gorham 1888: 60 [junior synonym]. — Alvarenga 1994: 36. — Skelley 1998b: 17.
Primary type
Lectotype, here designated (Fig. 37A)
BRAZIL • “TYPE. [printed] silaceus Ch [handwritten] \ TYPE [printed, blue label] \ LECTOTYPE [printed] Mycotretus silaceus Lacordaire, 1842 [red label, handwritten]”; UMCZ.
Remarks
Junior synonym of M. sobrinus (Guérin-Méneville, 1841) (Fig. 22E, see above).
description: Published as part of Pecci-Maddalena, Italo Salvatore de Castro, Lopes-Andrade, Cristiano & Skelley, Paul, 2023, Catalogue of Mycotretus Lacordaire, 1842 (Coleoptera: Erotylidae: Tritomini): an annotated, illustrated and historical approach, pp. 1-182 in European Journal of Taxonomy 876 (1) on page 159, DOI: 10.5852/ejt.2023.876.2149, http://zenodo.org/record/8095647
Additional file 4: Figure S1. of A novel quantification method for the total demethylation potential of aquatic sample extracts from Bohai Bay using the EGFP reporter gene
Creators: name: Qian, Yan
name: Xiaoli Wang
name: Zhanlu Lv
name: Guo, Chen
name: Han, Mei
name: Jiabing Wu
name: Yongjian Yang
name: Yishu Yang
name: Jiang, Yan
name: Yongjie Wei
name: Nie, Jing
name: Liang, Bao
name: Jinliang Zhang
name: Xianliang Wang
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: Aquatic sampling sites around the Haihe river estuary of Bohai Sea. All five sites are 15 km from the coastal line and 20 km apart. (PDF 755Â kb)
Additional file 11: Figure S5. of Single-cell analysis of long non-coding RNAs in the developing human neocortex
Creators: name: Siyuan Liu
name: Nowakowski, Tomasz
name: Pollen, Alex
name: Lui, Jan
name: Horlbeck, Max
name: Attenello, Frank
name: He, Daniel
name: Weissman, Jonathan
name: Kriegstein, Arnold
name: Diaz, Aaron
name: Lim, Daniel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Expression of lncRNAs and mRNAs in single cells and whole tissues. A Distributions of non-zero lncRNA (blue) and mRNA (red) expression in 276 single cells from neocortex. The median lncRNA expression and the median mRNA expression for each cell was compared as a ratio and summarized in Fig.Â 3b. B Distributions of non-zero lncRNA (blue) and mRNA (red) expression in eight bulk tissue RNA-seq samples using the same set of 1400 lncRNAs and 10929 mRNAs as in (A). C Distributions of non-zero lncRNA (blue) and mRNA (red) expression in in silico merged neocortex single cells. D Proportion of single neocortex cells that expressed each lncRNA (blue) and mRNA (red), binned by their expression levels in bulk tissues. E Distributions of housekeeping gene and lncRNA (F) expression levels in neocortex single cells, binned by log2(Normalized Countsâ  +â  1). Colors represent number of cells in each bin. Abundant lncRNAs were ranked by their median expression levels across 276 neocortex single cells. (PDF 257 kb)
Pennaria disticha Goldfuss 1820
Creators: name: Calder, Dale R.
name: Carlton, James T.
name: Keith, Inti
name: Ashton, Gail V.
name: Larson, Kristen
name: Ruiz, Gregory M.
name: Herrera, Esteban
name: Golfin, Geiner
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Cnidaria
Hydrozoa
Anthoathecata
Pennariidae
Pennaria
Pennaria disticha

description: Pennaria disticha Goldfuss, 1820
(Figure 2a)
Pennaria disticha Goldfuss, 1820: 89.
Type locality
Italy: Gulf of Naples (see Calder 2013, p. 7).
Material examined
Chatham Bay, dock 004, 1 colony, 2.8 cm high, without gonophores, coll. G. Ashton, #266339.
Remarks
The hydroid of Pennaria disticha Goldfuss, 1820 has in the past been considered essentially cosmopolitan in tropical to temperate waters. While the species is known to be invasive, barcoding studies reveal the existence of cryptic species within the binomen (Miglietta et al. 2015, 2019). In the analysis of Miglietta et al. (2019), specimens from the Pacific coast of Panama, in the Tropical Eastern Pacific, occurred in both a clade (1A) with other populations from Brazil, Florida, Hawaii, China Sea, and Mayotte in the Western Indian Ocean, and in another clade (2D) with specimens from North Carolina, the Caribbean, Atlantic Panama, Hawaii, Chuuk, Guam, American Samoa, and the Red Sea. Specimens from Italy (the type locality of the species) and elsewhere in the Mediterranean occurred in a separate clade (‘Clade 2C’), along with material from the Azores and the Gulf of Mexico. Taxonomic and nomenclatural issues arising from these results have yet to be resolved, however, and the name P. disticha has been retained for specimens examined here.
In the eastern Pacific, Pennaria disticha has been reported from San Francisco Bay, California, to Santa Elena Bay, Ecuador (Fraser 1937, 1938a, 1938c, 1947, 1948, as Pennaria tiarella). On the Pacific coast of Costa Rica, it has been reported from Port Culebra (Fraser (1938a) and Bahía Huevos at 10.64444°N, 85.69167°W (Kelmo and Vargas 2002). In the Galápagos Islands P. disticha is one of the most common and conspicuous species of hydroids on exposed coasts at depths ranging from the surface to 10 m, except on the westernmost Isla Fernandina (D. Calder, personal observations, 16–22 June 2001).
A species of many habitats, we regard P. disticha as cryptogenic in the Tropical Eastern Pacific (including in Cocos and the Galapagos Islands), pending further resolution of the taxonomy and geography of the multiple genetic clades detected to date.
Reported distribution
Cocos Island: first record.
Elsewhere: reported to be circumglobal in tropical and warm-temperate waters, although cryptic species appear to exist (Calder 2010; Miglietta et al. 2015, 2019).
description: Published as part of Calder, Dale R., Carlton, James T., Keith, Inti, Ashton, Gail V., Larson, Kristen, Ruiz, Gregory M., Herrera, Esteban & Golfin, Geiner, 2022, Biofouling hydroids (Cnidaria: Hydrozoa) from a Tropical Eastern Pacific island, with remarks on their biogeography, pp. 565-606 in Journal of Natural History 56 (9 - 12) on pages 572-573, DOI: 10.1080/00222933.2022.2068387, http://zenodo.org/record/7012486
Regulatory mechanisms of the exchange factor RasGRP1
Creators: name: Tazmini, Ghazaleh
Publisher: name: University of British Columbia
Year: 2008

description: RasGRP1 is an intracellular signaling protein expressed in lymphocytes that is responsible for activating Ras GTPases. Positive regulation of RasGRP 1 requires translocation to cellular membranes where lipid-anchored Ras can be accessed. Plasma membrane localization of RasGRP 1 in response to antigen receptors requires both the Cl domain and the plasma-membrane targeting (PT) domain. The Cl domain binds to diacylglycerol (DAG) at membranes. The PT domain binds its putative ligand at the plasma membrane and is negatively regulated by an adjacent suppressor of PT (SuPT) domain. RasGRP1 also contains a pair of EF-hands, with Ca²⁺-binding capability, but with no known regulatory role. In DT4O cells, RasGRP1 translocates to the plasma membrane and activates the Ras ERK pathway in response to B cell receptor (BCR) signaling. By introducing point mutations in the Ca²⁺-binding loops of each of the EF-hands, I found that a potential Ca²⁺- interaction loop in the first EF-hand is required for RasGRP1 translocation and the consequential activation of the Ras-ERK pathway in response to BCR signaling. However, RasGRP1 translocation is not regulated by BCR-generated Ca²⁺ flux. EF-hands were not required for Cl domain-mediated membrane localization, but were needed for PT-mediated plasma membrane targeting. EF-hands enhanced PT-domain mediated plasma membrane localization by repressing the SuPT domain. The REM and GEF domains, which co ordinately bind to and catalyze guanine nucleotide exchange on Ras GTPases, needed to be present and Ras-bound for this EF-hand mechanism to be effective. When not bound to Ras, the REM-GEF domain complex suppressed both plasma membrane and endomembrane targeting of RasGRP 1 by an EF-hand independent mechanism. Finally, membrane localization and activation of a naturally occurring splice variant of RasGRP 1, found overexpressed in systemic lupus erythematosus (SEE) patients, was examined. This splice variant lacks exon 11, which encodes the segment of RasGRP1 between the GEF domain and the first EF-hand. Removal of exon 11 resulted in a defect in plasma membrane localization that was partially overridden by deletion of SuPT, while membrane localization control via the REM-GEF complex was not affected. Therefore, exon 11 deletion via alternative splicing appears to functionally disable the first EF-hand of RasGRP1.
Myrmecridiales
Creators: name: Calabon, Mark S.
name: Jones, E. B. Gareth
name: Pang, Ka-Lai
name: Abdel-Wahab, Mohamed A.
name: Jin, Jing
name: Devadatha, Bandarupalli
name: Sadaba, Resurreccion B.
name: Apurillo, Carlo Chris
name: Hyde, Kevin D.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Sordariomycetes
Myrmecridiales

description: 2.2.6 Myrmecridiales (Sordariomycetes, Ascomycota)
The order Myrmecridiales (Sordariomycetes) includes one salt marsh fungus Myrmecridium schulzeri, an asexual morph with subhyaline, obovoid or fusiform, 1-celled, conidia that can be distinguished from Ramichloridium by having hyaline mycelium, pale brown to hyaline conidiogenous cells with pimple-like denticles (Arzanlou et al. 2007). Myrmecridium schulzeri is recorded for the first time as saprobic on Distichlis spicata (saltgrass) in Buenos Aires, Argentina (Calabon et al. 2021; ElÍades et al. 2007).
description: Published as part of Calabon, Mark S., Jones, E. B. Gareth, Pang, Ka-Lai, Abdel-Wahab, Mohamed A., Jin, Jing, Devadatha, Bandarupalli, Sadaba, Resurreccion B., Apurillo, Carlo Chris & Hyde, Kevin D., 2023, Updates on the classification and numbers of marine fungi, pp. 213-238 in Botanica Marina (Warsaw, Poland) (Warsaw, Poland) 66 (4) on page 215, DOI: 10.1515/bot-2023-0032, http://zenodo.org/record/11000251
Mycotretus singularis Lacordaire 1842
Creators: name: Pecci-Maddalena, Italo Salvatore de Castro
name: Lopes-Andrade, Cristiano
name: Skelley, Paul
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Erotylidae
Mycotretus
Mycotretus singularis

description: 208. Mycotretus singularis Lacordaire, 1842
Mycotretus singularis Lacordaire, 1842: 148. Type locality: “ Colombie ”.
Mycotretus singularis – Crotch 1876: 451. — Gemminger & Harold 1876: 3695. — Kuhnt 1909: 74; 1911: 53. — Blackwelder 1945: 467. — Alvarenga 1994: 35. — Skelley 1998b: 17.
Primary type
Lectotype, here designated (Fig. 37B)
COLOMBIA • “Nova Gr [handwritten] \ TYPE [blue label, printed] \ TYPE. [printed] Singularis R [handwritten] \ LECTOTYPE [printed] Mycotretus singularis Lacordaire, 1842 [red label, handwritten]”; UMCZ.
Distribution
Unknown locality in Colombia.
description: Published as part of Pecci-Maddalena, Italo Salvatore de Castro, Lopes-Andrade, Cristiano & Skelley, Paul, 2023, Catalogue of Mycotretus Lacordaire, 1842 (Coleoptera: Erotylidae: Tritomini): an annotated, illustrated and historical approach, pp. 1-182 in European Journal of Taxonomy 876 (1) on page 159, DOI: 10.5852/ejt.2023.876.2149, http://zenodo.org/record/8095647
Additional file 1: Table S1. of A novel quantification method for the total demethylation potential of aquatic sample extracts from Bohai Bay using the EGFP reporter gene
Creators: name: Qian, Yan
name: Xiaoli Wang
name: Zhanlu Lv
name: Guo, Chen
name: Han, Mei
name: Jiabing Wu
name: Yongjian Yang
name: Yishu Yang
name: Jiang, Yan
name: Yongjie Wei
name: Nie, Jing
name: Liang, Bao
name: Jinliang Zhang
name: Xianliang Wang
Publisher: name: Figshare
Year: 2015
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Quantitative real-time PCR of the EGFP mRNA for 5-AZA-CdR treated Hep G2 cell lines. (PDF 114Â kb)
Additional file 17: Figure S10. of Single-cell analysis of long non-coding RNAs in the developing human neocortex
Creators: name: Siyuan Liu
name: Nowakowski, Tomasz
name: Pollen, Alex
name: Lui, Jan
name: Horlbeck, Max
name: Attenello, Frank
name: He, Daniel
name: Weissman, Jonathan
name: Kriegstein, Arnold
name: Diaz, Aaron
name: Lim, Daniel
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Immunohistochemistry of maturing neuron marker ADRA2A. Immunohistochemistry of maturing neuron marker protein ADRA2A (left) compared to in situ hybridization against maturing neuron lncRNA LINC00599 (right, reproduced from Fig.Â 5). (PDF 952 kb)