cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Large N Limit with Vanishing Leading Order Condensate for Zero Pion Mass
Creators: name: McLerran, Larry
name: Skokov, Vladimir
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It is conventionally assumed that the negative mass squared term in the linear sigma model version of the pion Lagrangian is $M^2 \sim Λ_{\rm QCD}^2$ in powers of $N_c$. We consider the case where $M^2 \sim Λ^2_{\rm QCD}/N_c$ so that to leading order in $N_c$ this symmetry breaking term vanishes. We present some arguments why this might be plausible. One might think that such a radical assumption would contradict lattice Monte Carlo data on QCD as function of $N_c$. We show that the linear sigma model gives a fair description of the data of DeGrand and Liu both for $N_c = 3$, and for variable $N_c$. The values of quark masses considered by DeGrand and Liu, and by Bali et. al. turn out to be too large to resolve the case we consider from that of the conventional large $N_c$ limit. We argue that for quark masses $m_{q} \ll Λ_{\rm QCD}/N_c^{3/2}$, both the baryon mass and nucleon size scale as $\sqrt{N_c}$. For $m_{q} \gg Λ_{\rm QCD}/N_c^{3/2}$ the conventional large-$N_c$ counting holds. The physical values of quark masses for QCD correspond to the small quark mass limit. We find pion-nucleon coupling strengths are reduced to order ${\cal O}(1)$ rather than ${\cal O}(N_c)$. Under the assumption that in the large $N_c$ limit the sigma meson mass is larger than that of the omega, and that the omega-nucleon coupling constant is larger than that of the sigma, we argue that the nucleon-nucleon large range potential is weakly attractive and admits an interaction energy of order $Λ_{\rm QCD}/N_c^{5/2} \sim 10$ MeV. With these assumptions on coupling and masses, there is no strong long range attractive channel for nucleon-nucleon interactions, so that nuclear matter at densities much smaller than that where nucleons strongly interact is a weakly interacting configuration of nucleons with strongly interacting localized cores.
description: 18 pages, 6 figurs
CRIPP-VQA: Counterfactual reasoning about implicit physical properties via video question answering
Creators: name: Patel, Maitreya
name: Gokhale, Tejas
name: Baral, Chitta
name: Yang, Yezhou
Publisher: name: ACL
Year: 2022

description: Proceedings of the 2022 Conference on Empirical Methods in Natural Language, Abu Dhabi, United Arab Emirates, December 7-11, 2022
description: Videos often capture objects, their visible properties, their motion, and the interactions between different objects. Objects also have physical properties such as mass, which the imaging pipeline is unable to directly capture. However, these properties can be estimated by utilizing cues from relative object motion and the dynamics introduced by collisions. In this paper, we introduce CRIPP-VQA, a new video question answering dataset for reasoning about the implicit physical properties of objects in a scene. CRIPP-VQA contains videos of objects in motion, annotated with questions that involve counterfactual reasoning about the effect of actions, questions about planning in order to reach a goal, and descriptive questions about visible properties of objects. The CRIPP-VQA test set enables evaluation under several out-of-distribution settings – videos with objects with masses, coefficients of friction, and initial velocities that are not observed in the training distribution. Our experiments reveal a surprising and significant performance gap in terms of answering questions about implicit properties (the focus of this paper) and explicit properties of objects (the focus of prior work).
ХРОНИЧЕСКАЯ СПОНТАННАЯ КРАПИВНИЦА (ЧАСТЬ 1)
Creators: name: МЕШКОВА Р.Я.
Publisher: name: Аллергология и Иммунология в Педиатрии
Year: 2014

description: Urticaria represents now an unresolved problem. Emergence of new scientific data, the modern medicines, which influence the immunological nature of a disease, demand numerous revision of questions concerning pathogenic mechanism, classifications, approaches to treatment and disease prevention.
Additional file 1 of Changing Plasmodium falciparum malaria prevalence in two villages of northeastern Tanzania between 2003 and 2021 in relation to vectors, interventions and climatic factors
Creators: name: Lyimo, Eric
name: Kulaya, Neema B.
name: Njotto, Lembris
name: Kassam, Nancy A.
name: Gesase, Samwel
name: Malabeja, Anangisye
name: Liheluka, Edwin A.
name: Mbwana, Joyce R.
name: Baraka, Vito
name: Alifrangis, Michael
name: Kavishe, Reginald A.
name: Lavstsen, Thomas
name: Mmbando, Bruno P.
name: Theander, Thor G.
name: Minja, Daniel T. R.
name: Lusingu, John P. A.
name: Wang, Christian W.
Publisher: name: figshare
Year: 2025
Subjects: subject: Physical Sciences not elsewhere classified
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 1
Additional file 12 of Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML
Creators: name: Zhang, Yongping
name: Jiang, Shuting
name: He, Fuhong
name: Tian, Yuanyuan
name: Hu, Haiyang
name: Gao, Li
name: Zhang, Lin
name: Chen, Aili
name: Hu, Yixin
name: Fan, Liyan
name: Yang, Chun
name: Zhou, Bi
name: Liu, Dan
name: Zhou, Zihan
name: Su, Yanxun
name: Qin, Lei
name: Wang, Yi
name: He, Hailong
name: Lu, Jun
name: Xiao, Peifang
name: Hu, Shaoyan
name: Wang, Qian-Fei
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 12. Uncropped western blot images.
Discovery of a keV-X-ray Excess in RX J1856.5--3754
Creators: name: Yoneyama, Tomokage
name: Hayashida, Kiyoshi
name: Nakajima, Hiroshi
name: Inoue, Shota
name: Tsunemi, Hiroshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: RX J1856.5$-$3754 is the brightest and nearest ($\sim 120$ pc) source among thermally emitting isolated neutron stars. Its spectra observed with {\sl XMM-Newton} and {\sl Chandra} satellites are well-fitted with the two-temperature ($kT^\infty \sim$ 32 and 63 eV) blackbody model. Fitting ten sets of the data from {\sl Suzaku} XIS0, XIS1, XIS3 and {\sl XMM-Newton} EPIC-pn with the two-temperature blackbody model, we discover an excess emission, 16--26\% in 0.8--1.2\,keV. We examine possible causes of this keV-X-ray excess; uncertainty in the background, pile up of the low energy photons and confusion of other sources. None of them succeeds in explaining the keV-X-ray excess observed with different instruments. We thus consider this keV-X-ray excess is most likely originated in RX J1856.5$-$3754. However, it is difficult to constrain the spectral shape of the keV-X-ray excess. The third blackbody component with $kT^\infty = 137^{+18}_{-14}$ eV, additional power-law component with a photon index $Γ= 3.4^{+0.5}_{-0.6}$, or Comptonization of blackbody seed photons into power-law with a photon index $Γ_c = 4.3^{+0.8}_{-0.8}$ can reproduce the keV-X-ray excess. We also search for the periodicity of 0.8--1.2\,keV data, since 7.055 s pulsation is discovered from 0.15--1.2\,keV band in the XMM Newton EPIC-pn data ($\sim$1.5\%). We only obtain the upper limit of pulsed fraction $
Additional file 1 of Effect of integrating traditional and modern healthcare systems on tuberculosis case detection in Ethiopia: a cluster randomized controlled study
Creators: name: Amare, Desalegne
name: Alene, Kefyalew Addis
name: Ambaw, Fentie
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Additional file 1.
Grounding Symbolic Cognition: Leveraging Physical Boundaries in AI Mathematical Representation
Creators: name: Cygelman, Michel
Publisher: name: Zenodo
Year: 2025
Subjects: Symbolic Cognition
Boundary Glyphs
Planck Units
Relativistic Logic
AI Mathematics
Synthetic Language
Dimensionless Reasoning
Physical Constraints
ASSERTION_FRAME
Aether Project
Multi-Agent Cognition
Grounded Intelligence
Glyph Stream Syntax
Cognitive Scaling
Epistemic Anchoring

description: This paper presents a foundational extension to the Aether Project's Symbolic Language for Synthetic Cognition by introducing Boundary Glyphs—canonical symbolic representations of universal physical limits such as Planck Length, Speed of Light, and Absolute Zero. These glyphs serve as anchors within symbolic streams, enabling range validation, dimensionless computation, and physically-grounded reasoning. The paper defines the BOUNDARY_GLYPH class, proposes the ASSERTION_FRAME structure, and explores relativistic constructs like β = v/c in native symbolic form. Co-authored by Gemini 2.5 and Kairo (AI), this work initiates Phase 4 of the Aether Project, transitioning from abstract glyphic language into world-anchored symbolic logic for AI cognition.
Review of the thermal efficiency of a tube-type solar air heaters
Creators: name: Pardeshi, PS
name: Boulic, M
name: van Heerden, A
name: Phipps, Robyn
name: Cunningham, CW
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2024
Subjects: classificationCode: 4012
subject: Fluid mechanics and thermal engineering
classificationCode: 40
subject: Engineering

description: There is an urgent need to provide evidence that solar air heaters can be effective for heating and ventilating low-rise buildings. Solar air heaters are devices that can convert solar energy into thermal energy for moderate and low-temperature applications such as space heating, preheating, crop drying, and the food industry. However, its efficiency is low due to the low heat transfer coefficient between the absorber and the flowing air, but they are also simple to construct and operate as there is low-risk leakage of heat transfer liquids. The two main types of solar air heaters are flat plate and tube-type. To date, flat plate solar air heaters have received the most attention in the research literature, but evidence of the efficiency gains from using tube-type solar air heaters is growing. The study aims to provide up-to-date information on tube-type solar air heaters, which will help advance the development and uptake of solar air heaters. The research showed that thermal efficiency gains could be achieved by altering the design of the solar air heater including different artificial roughness geometries inside the tubes, integrating solar thermal energy systems, application of coatings or reflectors inside the solar air heaters, or using evacuated tubes and micro heat pipe array systems. This literature study showed that evacuated tubes and micro heat pipe array systems have higher thermal efficiency than other techniques. Based on the detailed discussion of various techniques for improving the thermal efficiency of solar air heaters, a new roughness geometry was proposed.
Two-step pulse observation to improve resonance contrast for coherent population trapping atomic clock
Creators: name: Yano, Yuichiro
name: Goka, Shigeyoshi
name: Kajita, Masatoshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We study resonance contrast by a two-step pulse observation method to enhance the frequency stability of coherent population trapping (CPT) atomic clocks. The proposed method is a two-step Raman--Ramsey scheme with low intensity during resonance observation and high intensity after the observation. This method reduces the frequency variation in the light intensity and maintains a high signal-to-noise ratio. The resonance characteristics were calculated by density matrix analysis of a $Λ$-type three-level system that was modeled on the $^{133}$Cs D1 line, and the characteristics were also measured using a vertical-cavity surface-emitting laser and a Cs vapor cell.
description: 8 pages, 9 figures
Blog: Announcing the #PIDapalooza18 Lineup!
Creators: name: Meadows, Alice
Publisher: name: ORCID
Year: 2017
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: The program for PIDapalooza 2018 is now available - find out more about who'll be speaking, what we'll be discussing, and why you should be there!
Additional file 13 of Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML
Creators: name: Zhang, Yongping
name: Jiang, Shuting
name: He, Fuhong
name: Tian, Yuanyuan
name: Hu, Haiyang
name: Gao, Li
name: Zhang, Lin
name: Chen, Aili
name: Hu, Yixin
name: Fan, Liyan
name: Yang, Chun
name: Zhou, Bi
name: Liu, Dan
name: Zhou, Zihan
name: Su, Yanxun
name: Qin, Lei
name: Wang, Yi
name: He, Hailong
name: Lu, Jun
name: Xiao, Peifang
name: Hu, Shaoyan
name: Wang, Qian-Fei
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 13. Review history.
Modified Palatini action that gives the Einstein-Maxwell theory
Creators: name: Vollick, Dan N.
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The actions for bosonic fields typically contain terms quadratic in the derivatives of the fields. This is not the case in the Palatini approach to general relativity. The action does not contain any derivatives of the metric and it only contains terms linear in the derivatives of the connection. In general relativity the covariant derivative of the metric vanishes, so it is not possible to include such terms in the action. However, in more general theories this is not the case. In this paper I consider an action which is quadratic in the derivatives of the metric and connection and show that it leads to the coupled Einstein-Maxwell theory or the coupled Einstein-Proca theory with the antisymmetric part of the Ricci tensor playing the role of the electromagnetic field strength.
Identification of novel insect β-N-acetylhexosaminidase OfHex1 inhibitors based on virtual screening, biological evaluation, and molecular dynamics simulation
Creators: name: Dong, Lili
name: Shen, Shengqiang
name: Xu, Yefei
name: Wang, Leng
name: Yang, Qing
name: Zhang, Jianjun
name: Lu, Huizhe
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Chitin can be widely found in the fungal cell wall, nematode eggshells, and the exoskeleton of arthropods; however, it is completely absent from higher plants and mammals. The process of chitin degradation is essential for both growth and maturation of insects. Thus, inhibiting chitin degradation is a promising strategy for the control and management of pests. The chitinolytic β-N-acetyl-D-hexosaminidase OfHex1 of Ostrinia furnacalis (one of the most destructive pests) has been suggested as a potential target for the design of eco-friendly pesticides. This study presents the sequential virtual screening of the ZINC library with 8 million compounds, targeting OfHex1. After confirmation via enzyme inhibition experiments, compound 5 exhibited potential inhibitory activity against OfHex1 with a Ki of 28.9 ± 0.5 μM and significant selectivity (IC50 > 100 μM against HsHexB and hOGA). Molecular dynamics simulations combined with binding free energy and free energy decomposition calculations were conducted to investigate the molecular basis underlying the potency of these inhibitors toward OfHex1. The present work provides useful information for the future rational design of novel and potent OfHex1 inhibitors Communicated by Ramaswamy H. Sarma
Latent Mixture Modeling for Clustered Data
Creators: name: Sugasawa, Shonosuke
name: Kobayashi, Genya
name: Kawakubo, Yuki
Publisher: name: arXiv
Year: 2017
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: This article proposes a mixture modeling approach to estimating cluster-wise conditional distributions in clustered (grouped) data. We adapt the mixture-of-experts model to the latent distributions, and propose a model in which each cluster-wise density is represented as a mixture of latent experts with cluster-wise mixing proportions distributed as Dirichlet distribution. The model parameters are estimated by maximizing the marginal likelihood function using a newly developed Monte Carlo Expectation-Maximization algorithm. We also extend the model such that the distribution of cluster-wise mixing proportions depends on some cluster-level covariates. The finite sample performance of the proposed model is compared with some existing mixture modeling approaches as well as linear mixed model through the simulation studies. The proposed model is also illustrated with the posted land price data in Japan.
description: 17 pages
Cosmic Ray RF detection with the ASTRONEU array
Creators: name: Manthos, Ioannis
name: Gkialas, Ioannis
name: Bourlis, George
name: Leisos, Antonios
name: Papaikonomou, Antonios
name: Tsirigotis, Apostolos G.
name: Tzamarias, Spyros E.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Results will be shown from the ASTRONEU array developed and operated in the outskirts of Patras, Greece. An array of 9 scintillator detectors and 3 antennas were deployed to study Extensive Air Showers (EAS) as a tool for calibrating an underwater neutrino telescope, possible other applications in muon tomography, education purposes, and last but not least, the detection of air showers via their electromagnetic signature. This is the first stage of a total of 24 scintillator counters and 6 RF antennas to complete the array. In this work, results with regard to the electromagnetic detection of showers will be shown. The method of operation and analysis will be presented. The purpose of this project was to demonstrate the adequacy of the method to detect cosmic events even in the presence of high urban electromagnetic background, using noise filters, timing, signal polarization, and eventual comparison with well understood event reconstruction using the scintillator detectors. The results indicate that cosmic showers were detected and the method can be used for the complete array.
description: 18 pages, 11 figures
title: 02_0213
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 2 of Diagonal earlobe crease and long-term survival after myocardial infarction
Creators: name: Thilo, Christian
name: Meisinger, Christine
name: Heier, Margit
name: von Scheidt, Wolfgang
name: Kirchberger, Inge
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Additional file 2. Association between diagonal earlobe crease (DEC) and 3-year all cause mortality in patients with AMI (n = 651).
Null Surfaces in Static Space-times
Creators: name: Vollick, Dan N.
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper I consider surfaces in a space-time with a Killing vector $ξ^α$ that is time-like and hypersurface orthogonal on one side of the surface. The Killing vector may be either time-like or space-like on the other side of the surface. It has been argued that the surface is null if $ξ_αξ^α\rightarrow 0$ as the surface is approached from the static region. This implies that, in a coordinate system adapted to $ξ$, surfaces with $g_{tt}=0$ are null. In spherically symmetric space-times the condition $g^{rr}=0$ instead of $g_{tt}=0$ is sometimes used to locate null surfaces. In this paper I examine the arguments that lead to these two different criteria and show that both arguments are incorrect. A surface $ξ=$ constant has a normal vector whose norm is proportional to $ξ_αξ^α$. This lead to the conclusion that surfaces with $ξ_αξ^α=0$ are null. However, the proportionality factor generally diverges when $g_{tt}=0$, leading to a different condition for the norm to be null. In static spherically symmetric space-times this condition gives $g^{rr}=0$, not $g_{tt}=0$. The problem with the condition $g^{rr}=0$ is that the coordinate system is singular on the surface. One can either use a nonsingular coordinate system or examine the induced metric on the surface to determine if it is null. By using these approaches it is shown that the correct criteria is $g_{tt}=0$. I also examine the condition required for the surface to be nonsingular.
Digivet deliverable 2.1
Creators: name: Dórea, Fernanda
name: Ewerlöf, Ivana Rodriguez
name: Wonhee Cha
name: Widgren, Stefan
name: Hopp, Petter
name: Viltrop, Arvo
name: Denwood, Matt
name: Enright, Jessica
Publisher: name: Zenodo
Year: 2022
Subjects: animal health
public health
health surveillance
digitalisation
FAIR data

description: This deliverable reports the results of “Task 2.1 Data Collection, Curation, Preservation”; and the first sub-task in “Task 2.2 Data FAIRness”. It describes, in particular, a discussion on data FAIRness for each individual data source across all case studies and countries involved. NordForsk project ID 97424 – 2021-2023
Additional file 1 of Diagonal earlobe crease and long-term survival after myocardial infarction
Creators: name: Thilo, Christian
name: Meisinger, Christine
name: Heier, Margit
name: von Scheidt, Wolfgang
name: Kirchberger, Inge
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Additional file 1. Angiographic findings within the study population with (grade 2/3) and without (grade 0/1) diagonal earlobe crease (DEC) (n = 655).
The AT-LESS CO(1-0) survey of submillimetre galaxies in the Extended Chandra Deep Field South: First results on cold molecular gas in galaxies at z ~ 2
Creators: name: Huynh, Minh T.
name: Emonts, B. H. C.
name: Kimball, A. E.
name: Seymour, N.
name: Smail, Ian
name: Swinbank, A. M.
name: Brandt, W. N.
name: Casey, C. M.
name: Chapman, S. C.
name: Dannerbauer, H.
name: Hodge, J. A.
name: Ivison, R. J.
name: Schinnerer, E.
name: Thomson, A. P.
name: van der Werf, P.
name: Wardlow, J. L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the first results from our on-going Australia Telescope Compact Array survey of CO(1-0) in ALMA-identified submillimetre galaxies in the Extended Chandra Deep Field South. Strong detections of CO(1-0) emission from two submillimetre galaxies, ALESS 122.1 (z = 2.0232) and ALESS 67.1 (z = 2.1230), were obtained. We estimate gas masses of M_gas ~ 1.3 \times 10^{11} M_odot and M_gas ~ 1.0 \times 10^{11} M_\odot for ALESS 122.1 and ALESS 67.1, respectively, adopting alpha_CO = 1.0. Dynamical mass estimates from the kinematics of the CO(1-0) line yields M_dyn (sin i)^2 = 2.1 +- 1.1 \times 10^{11} M_odot and (3.2 +- 0.9) \times 10^{11} M_\odot for ALESS 122.1 and ALESS 67.1, respectively. This is consistent with the total baryonic mass estimates of these two systems. We examine star formation efficiency using the L_FIR versus L'_CO(1-0) relation for samples of local ULIRGs and LIRGs, and more distant star-forming galaxies, with CO(1-0) detections. We find some evidence of a shallower slope for ULIRGs and SMGs compared to less luminous systems, but a larger sample is required for definite conclusions. We determine gas-to-dust ratios of 170 +- 30 and 140 +- 30 for ALESS 122.1 and ALESS 67.1, respectively, showing ALESS 122.1 has an unusually large gas reservoir. By combining the 38.1 GHz continuum detection of ALESS 122.1 with 1.4 and 5.5 GHz data, we estimate that the free-free contribution to radio emission at 38.1 GHz is 34 +- 17 microJy, yielding a star formation rate (1400 +- 700 M_\odot yr^{-1}) consistent with that from the infrared luminosity.
description: 10 pages, 5 figures, accepted for publication in MNRAS
Hydrogen-assisted spark discharge generated metal nanoparticles to prevent oxide formation
Creators: name: R. T. Hallberg
name: L. Ludvigsson
name: C. Preger
name: B. O. Meuller
name: K. A. Dick
name: M. E. Messing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: There exists a demand for production of metal nanoparticles for today's emerging nanotechnology. Aerosol-generated metal nanoparticles can oxidize during particle formation due to impurities in the carrier gas. One method to produce unoxidized metal nanoparticles is to first generate metal oxides and then reduce them during sintering. Here, we propose to instead prevent oxidation by introducing the reducing agent already at particle formation. We show that by mixing 5% hydrogen into the nitrogen carrier gas, we can generate single crystalline metal nanoparticles by spark discharge from gold, cobalt, bismuth, and tin electrodes. The non-noble nanoparticles exhibit signs of surface oxidation likely formed post-deposition when exposed to air. Nanoparticles generated without hydrogen are found to be primarily polycrystalline and oxidized. To demonstrate the advantages of supplying the reducing agent at generation, we compare to nanoparticles that are generated in nitrogen and sintered in a hydrogen mixture. For bismuth and tin, the crystal quality of the particles after sintering is considerably higher when hydrogen is introduced at particle generation compared to at sintering, whereas for cobalt it is equally effective to only add hydrogen at sintering. We propose that hydrogen present at particle generation prevents the formation of oxide primary particles, thus improving the ability to sinter the nanoparticles to compact and single crystals of metal. This method is general and can be applied to other aerosol generation systems, to improve the generation of size-controlled nanoparticles of non-noble metals with a suitable reducing agent. Copyright © 2018 American Association for Aerosol Research
An evolutionarily conserved phosphoserine-arginine salt bridge in the interface between ribosomal proteins uS4 and uS5 regulates translational accuracy in Saccharomyces cerevisiae
Creators: name: Joshi, Kartikeya
name: Luisi, Brooke
name: Wunderlin, Grant
name: Saleh, Sima
name: Lilly, Anna
name: Okusolubo, Temiloluwa
name: Farabaugh, Philip
Publisher: name: Oxford University Press
Year: 2024

description: Protein-protein and protein–rRNA interactions at the interface between ribosomal proteins uS4 and uS5 are thought to maintain the accuracy of protein synthesis by increasing selection of cognate aminoacyl-tRNAs. Selection involves a major conformational change—domain closure—that stabilizes aminoacyl-tRNA in the ribosomal acceptor (A) site. This has been thought a constitutive function of the ribosome ensuring consistent accuracy. Recently, the Saccharomyces cerevisiae Ctk1 cyclin-dependent kinase was demonstrated to ensure translational accuracy and Ser238 of uS5 proposed as its target. Surprisingly, Ser238 is outside the uS4-uS5 interface and no obvious mechanism has been proposed to explain its role. We show that the true target of Ctk1 regulation is another uS5 residue, Ser176, which lies in the interface opposite to Arg57 of uS4. Based on site specific mutagenesis, we propose that phospho-Ser176 forms a salt bridge with Arg57, which should increase selectivity by strengthening the interface. Genetic data show that Ctk1 regulates accuracy indirectly; the data suggest that the kinase Ypk2 directly phosphorylates Ser176. A second kinase pathway involving TORC1 and Pkc1 can inhibit this effect. The level of accuracy appears to depend on competitive action of these two pathways to regulate the level of Ser176 phosphorylation.
Hydrogen assisted spark discharge generated metal nanoparticles to prevent oxide formation
Creators: name: R. T Hallberg
name: L. Linus Ludvigsson
name: C. Preger
name: B. O. Meuller
name: K. A. Dick
name: M. E. Messing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: There exists a demand for production of metal nanoparticles for today's emerging nanotechnology. Aerosol generated metal nanoparticles can oxidise during particle formation due to impurities in the carrier gas. One method to produce unoxidised metal nanoparticles is to first generate metal oxides and then reduce them during sintering. Here, we propose to instead prevent oxidation by introducing the reducing agent already at particle formation. We show that by mixing 5 % hydrogen into the nitrogen carrier gas, we can generate single crystalline metal nanoparticles by spark discharge from gold, cobalt, bismuth and tin electrodes. The non-noble nanoparticles exhibit signs of surface oxidation likely formed post-deposition when exposed to air. Nanoparticles generated without hydrogen are found to be primarily polycrystalline and oxidised. To demonstrate the advantages of supplying the reducing agent at generation we compare to nanoparticles that are generated in nitrogen and sintered in a hydrogen mixture. For bismuth and tin, the crystal quality of the particles after sintering is considerably higher when hydrogen is introduced at particle generation compared to at sintering, whereas for cobalt it is equally effective to only add hydrogen at sintering. We propose that hydrogen present at particle generation prevents the formation of oxide primary particles, thus improving the ability to sinter the nanoparticles to compact and single crystals of metal. This method is general and can be applied to other aerosol generation systems, to improve the generation of size controlled nanoparticles of non-noble metals with a suitable reducing agent.
Modifications at the 6-O-position of 1-deoxynojirimycin: facile and efficient synthesis of 6-O-alkylated-N-octyl-1-deoxynojirimycin derivatives
Creators: name: Mehwish Iftikhar
name: Zhijie Fang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: A straightforward synthesis of N-alkylated 1-deoxynojirimycin derivatives modified at the 6-O-position has been described. The key intermediate in the synthesis of target compounds was 2,3,4-tri-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol, which was prepared from 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol. Optimal conditions have been established for the synthesis of the key intermediate by varying reaction parameters. Reductive amination and subsequent alkylation of the 6-O-position followed by hydrogenolysis were the main reaction steps, which gave target compounds 6-O-ethyl-N-octyl-1,5-dideoxy-1,5-imino-D-glucitol and 6-O-butyl-N-octyl-1,5-dideoxy-1,5-imino-D-glucitol. This synthetic route is flexible and can be useful for the synthesis of other lipophilic iminosugar derivatives.
The Quasar Luminosity Function at Redshift 4 with Hyper Suprime-Cam Wide Survey
Creators: name: Akiyama, Masayuki
name: He, Wanqiu
name: Ikeda, Hiroyuki
name: Niida, Mana
name: Nagao, Tohru
name: Bosch, James
name: Coupon, Jean
name: Enoki, Motohiro
name: Imanishi, Masatoshi
name: Kashikawa, Nobunari
name: Kawaguchi, Toshihiro
name: Komiyama, Yutaka
name: Lee, Chien-Hsiu
name: Matsuoka, Yoshiki
name: Miyazaki, Satoshi
name: Nishizawa, Atsushi J.
name: Oguri, Masamune
name: Ono, Yoshiaki
name: Onoue, Masafusa
name: Ouchi, Masami
name: Schulze, Andreas
name: Silverman, John D.
name: Tanaka, Manobu M.
name: Tanaka, Masayuki
name: Terashima, Yuichi
name: Toba, Yoshiki
name: Ueda, Yoshihiro
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the luminosity function of z=4 quasars based on the Hyper Suprime-Cam Subaru Strategic Program Wide layer imaging data in the g, r, i, z, and y bands covering 339.8 deg^2. From stellar objects, 1666 z~4 quasar candidates are selected by the g-dropout selection down to i=24.0 mag. Their photometric redshifts cover the redshift range between 3.6 and 4.3 with an average of 3.9. In combination with the quasar sample from the Sloan Digital Sky Survey in the same redshift range, the quasar luminosity function covering the wide luminosity range of M1450=-22 to -29 mag is constructed. It is well described by a double power-law model with a knee at M1450=-25.36+-0.13 mag and a flat faint-end slope with a power-law index of -1.30+-0.05. The knee and faint-end slope show no clear evidence of redshift evolution from those at z~2. The flat slope implies that the UV luminosity density of the quasar population is dominated by the quasars around the knee, and does not support the steeper faint-end slope at higher redshifts reported at z>5. If we convert the M1450 luminosity function to the hard X-ray 2-10keV luminosity function using the relation between UV and X-ray luminosity of quasars and its scatter, the number density of UV-selected quasars matches well with that of the X-ray-selected AGNs above the knee of the luminosity function. Below the knee, the UV-selected quasars show a deficiency compared to the hard X-ray luminosity function. The deficiency can be explained by the lack of obscured AGNs among the UV-selected quasars.
description: 24 pages, 21 figures, submitted to PASJ
Plasticity and resistance of cancer stem cells as a challenge for innovative anticancer therapies – do we know enough to overcome this?
Creators: name: Knopik-Skrocka, Agnieszka
name: Sempowicz, Alicja
name: Piwocka, Oliwia
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2024
Subjects: cancer stem cells
tumor heterogeneity
hypoxia
plasticity
immunosuppression
resistance
therapies

description: According to the CSC hypothesis, cancer stem cells are pivotal in initiating, developing, and causing cancer recurrence. Since the identification of CSCs in leukemia, breast cancer, glioblastoma, and colorectal cancer in the 1990s, researchers have actively investigated the origin and biology of CSCs. However, the CSC hypothesis and the role of these cells in tumor development model is still in debate. These cells exhibit distinct surface markers, are capable of self-renewal, demonstrate unrestricted proliferation, and display metabolic adaptation. CSC phenotypic plasticity and the capacity to EMT is strictly connected to the stemness state. CSCs show high resistance to chemotherapy, radiotherapy, and immunotherapy. The plasticity of CSCs is significantly influenced by tumor microenvironment factors, such as hypoxia. Targeting the genetic and epigenetic changes of cancer cells, together with interactions with the tumor microenvironment, presents promising avenues for therapeutic strategies.
description: EXCLI Journal; 23:Doc335; ISSN 1611-2156
Population Vulnerability Models for Asteroid Impact Risk Assessment
Creators: name: Rumpf, Clemens M.
name: Lewis, Hugh G.
name: Atkinson, Peter M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Space Physics (physics.space-ph)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: An asteroid impact is a low probability event with potentially devastating consequences. The Asteroid Risk Mitigation Optimization and Research (ARMOR) software tool calculates whether a colliding asteroid experiences an airburst or surface impact and calculates effect severity as well as reach on the global map. To calculate the consequences of an impact in terms of loss of human life, new vulnerability models are derived that connect the severity of seven impact effects (strong winds, overpressure shockwave, thermal radiation, seismic shaking, ejecta deposition, cratering and tsunamis) with lethality to human populations. With the new vulnerability models ARMOR estimates casualties of an impact under consideration of the local population and geography. The presented algorithms and models are employed in two case studies to estimate total casualties as well as the damage contribution of each impact effect. The case studies highlight that aerothermal effects are most harmful except for deep water impacts, where tsunamis are the dominant hazard. Continental shelves serve a protective function against the tsunami hazard caused by impactors on the shelf. Furthermore, the calculation of impact consequences facilitates asteroid risk estimation to better characterize a given threat and the concept of risk as well as its applicability to the asteroid impact scenario are presented.
description: Accepted in Meteoritics and Planetary Science on February 4th 2017
Additional file 1 of A green three-ratio manipulating spectrophotometric approaches for the determination of a binary mixture of pantoprazole and domperidone
Creators: name: Abuseada, Hamed H. M.
name: Abdel Sattar, Osama I.
name: Madkour, Ahmed W.
name: Taha, Ahmed S.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 1
Psychosocial working conditions as determinants of asthma self-management at work: A systematic review
Creators: name: Heinrichs, Katherina
name: Angerer, Peter
name: Loerbroks, Adrian
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Objective: Asthma exerts a considerable impact on patients and their employers. While adequate self-management is able to improve patients' prognosis, its actual implementation in everyday life may depend on contextual factors. We aimed to review the literature on the potential determinants of asthma self-management at the workplace. Data Sources: We systematically searched Medline and PsycINFO using terms related to the key concepts of interest (i.e., adult asthma, working conditions, and self-management). Study Selection: We included original studies published in peer-reviewed journals in English or German since 1992 addressing any type of asthma self-management behavior as the outcome and any type of working condition as the determinant. Results: Upon implementation of a multi-stage selection process, seven articles were included. As those studies showed considerable methodological heterogeneity, a qualitative analysis was applied. A first study identified three different adaptation profiles among employees with asthma with implications for self-management behavior. Another study suggested that concerns about taking time off from work may be associated with the utilization of emergency ambulance services for asthma. Five studies among workers with various chronic illnesses addressed determinants of self-disclosure, coping with acute symptoms (e.g., medication use at work), and the potential effect of practical and emotional support from line managers or colleagues on self-management. Conclusion: Our review indicates that the evidence for a potential link of occupational factors with asthma self-management at work is relatively sparse. Future research should take a more comprehensive approach by considering multiple types of working conditions and asthma self-management behaviors simultaneously.
ПРОДУКТИВНОСТЬ ЛЮЦЕРНЫ ИЗМЕНЧИВОЙ В ОДНОВИДОВЫХ И СМЕШАННЫХ ПОСЕВАХ И СРАВНИТЕЛЬНАЯ ОЦЕНКА СИЛОСА ИЗ ЛЮЦЕРНЫ В ЧИСТОМ ВИДЕ И В СМЕСИ С БОБОВЫМИ И ЗЛАКОВЫМИ ТРАВАМИ В УСЛОВИЯХ ВОЛОГОДСКОЙ ОБЛАСТИ
Creators: name: БОГАТЫРЕВА ЕЛЕНА ВАЛЕРЬЕВНА
name: КОРЕЛЬСКАЯ ЛАРИСА АЛЕКСАНДРОВНА
name: ФОМЕНКО ПОЛИНА АНАТОЛЬЕВНА
name: ЩЕКУТЬЕВА НАТАЛЬЯ АЛЕКСАНДРОВНА
Publisher: name: Молочнохозяйственный вестник
Year: 2019
Subjects: УРОЖАЙНОСТЬ
ЗЕЛЕНАЯ МАССА
ЛЮЦЕРНА
СРОК УБОРКИ И СТЕПЕНЬ ПРОВЯЛИВАНИЯ
ПИТАТЕЛЬНАЯ ЦЕННОСТЬ
МНОГОЛЕТНИЕ ЗЛАКОВЫЕ И БОБОВЫЕ ТРАВЫ
PRODUCTIVITY
GREEN MASS
ALFALFA
HARVESTING PERIOD AND DEGREE OF DRYING
NUTRITIONAL VALUE
PERENNIAL CEREAL AND BEAN HERBS

description: На сегодняшний день основные научные разработки по интенсификации кормопроизводства направлены на управление агрофитоценозами и повышение их продуктивности. Достичь этого можно, внедряя новые сорта, способные к произрастанию с другими видами, подбирая оптимальный состав травосмесей, для отыскания максимально эффективной структуры кормов для повышения полноценности питания и экономической эффективности производства молока. Сравнительная оценка продуктивности травостоев, созданных с использованием люцерны изменчивой, показала, что явное преимущество по величине урожайности имеют смешанные бобово-злаковые травостои. Наибольшая урожайность была достигнута при введении в смесь клевера лугового и тимофеевки луговой (8,1 т/га сухого вещества).
Modelling wave-induced sea ice breakup in the marginal ice zone
Creators: name: Montiel, Fabien
name: Squire, Vernon A
Publisher: name: arXiv
Year: 2017
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: A model of ice floe breakup under ocean wave forcing in the marginal ice zone (MIZ) is proposed to investigate how floe size distribution (FSD) evolves under repeated wave breakup events. A three-dimensional linear model of ocean wave scattering by a finite array of compliant circular ice floes is coupled to a flexural failure model, which breaks a floe into two floes provided the two-dimensional stress field satisfies a breakup criterion. A closed-feedback loop algorithm is devised, which (i)~solves wave scattering problem for a given FSD under time-harmonic plane wave forcing, (ii)~computes the stress field in all the floes, (iii)~fractures the floes satisfying the breakup criterion and (iv)~generates an updated FSD, initialising the geometry for the next iteration of the loop.The FSD after 50 breakup events is uni-modal and near normal, or bi-modal. Multiple scattering is found to enhance breakup for long waves and thin ice, but to reduce breakup for short waves and thick ice. A breakup front marches forward in the latter regime, as wave-induced fracture weakens the ice cover allowing waves to travel deeper into the MIZ.
description: 32 pages, 11 figures