cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Free vibration analysis of rectangular orthotropic cantilever plates with point supports.
Creators: name: Nguyen, Khang V.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Engineering, Mechanical.

description: The free vibration analysis of rectangular plates has been of interest to many scholars and practitioners over the years due to their wide range of applications. However, most of the studies involve the typical case of isotropy. A study has been done in the analysis of free vibration of orthotropic cantilever plates with internal point supports. The analysis makes use of the Superposition Method which, by superimposing appropriate building blocks, can provide "exact" analytical solution to this problem of orthotropy. In each case of symmetric and antisymmetric vibration modes under study, three different plate problems whose Levy-type solutions can be obtained, are superimposed. The constants in each solution, created during their boundary condition formulations, are adjusted in such a way so their combination would provide boundary conditions the same to those required for the cantilever plate. Upon superimposing, an eigenvalue matrix is created which allows the eigenvalues to be determined. Accuracy of the resultant eigenvalues is verified by recognising that the governing differential equation is satisfied exactly and that the required plate boundary conditions are satisfied to certain desired degree of exactitude. The objective of this thesis is to describe the necessary modifications to adapt the superposition method to orthotropic plate problems, and to show the mathematical procedures employed in the analysis. In addition, the results of some representative frequency and mode shape studies will be presented which include a wide range of plate geometries and various levels of orthotropy.
Grade of service of a telephone exchange.
Creators: name: Lee, Lansun.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1967
Subjects: subject: Engineering, Electronics and Electrical.

description: This project is concerned with the estimation of the grade of service given to the subscribers in a telephone exchange. The analytical models used are (a) the probability linear graph for lost calls and (b) the traffic flow graph for delayed calls. Both of these models are expressed in terms of the congestion functions of the sub-units of the switching system in the exchange. When these models are used, the engineering procedure of determining the quantity of equipment for the switching system in the exchange to satisfy the objective grade of service is simple. The switching system in the exchange may be divided into three major sub-units: the trunk groups, the switching network, and the common control. The congestion functions for these sub-units are discussed. The structure and the mode of operation for these sub-units are usually very complex, so that the congestion functions for these units can only be approximated. Thus, the overall grade of service estimated this way is only an approximation. Finally, the procedure of estimating the overall grade of service of an exchange is demonstrated by considering a simple hypothetical telephone switching system. The main contributions in this thesis are: (1) The traffic flow graph: This graph is used as the model for estimating the grade of service for delayed calls in an exchange. It can also be used for approximating the waiting time distribution for a given waiting system. (2) The equivalent trunk technique: This technique is shown to be reasonably accurate and simple for use in computing the trunk group congestion distribution when the trunk group is arranged in grading. (3) A method of approximating network blocking probability: This method can be used to approximate the blocking probability of any complex switching network. It is simple and inexpensive and produces reasonably accurate results. (4) Single linking stage network loaded with multitype of traffic: When some types of traffic require the service of more than one link at a time, the network for these types of traffic is blocked even if there are some idle links in the network. Extremely poor approximation will result if the usual assumption of independent busy links is used for calculating the blocking probability. In this thesis, such a network is analysed and a better approximation for computing the blocking probability is given. (5) General case approach for determining waiting time distribution for a single server delay system: Such a single server delay system is analysed. This aids one to the understanding of the congestion processes producing delays.
title: Handlungsansätze für die Förderung und Unterstützung innovativer gemeinwohlorientierter Initiativen
title: Handlungsansätze für die Förderung und Unterstützung innovativer gemeinwohlorientierter Initiativen
titleType: AlternativeTitle
Creators: name: Rückert-John, Jana
name: Peuker, Birgit
name: Egermann, Markus
Publisher: name: Umweltbundesamt
Year: 2021
Subjects: subject: Handlungsansätze
subject: Förderung
subject: Unterstützung
subject: gemeinwohlorientierte Initiativen
subject: Nachhaltigkeit | Strategien | Internationales

description: Die Broschüre richtet sich an Akteure aus Zivilgesellschaft, Sozialunternehmen sowie (Umwelt-) Politik und -Verwaltung. Sie liefert Handlungsempfehlungen, wie gemeinwohlorientierte Initiativen (z. B. offene Werkstätten, Gemeinschaftsgärten, Online-Plattformen für Tausch und Verleih oder genossenschaftliche Wohnprojekte) unterstützt und ihr Beitrag für sozial-ökologische Transformationsprozesse gestärkt werden können. Die Handlungsansätze zeigen u.a., wie sich sozial-ökologische Wirkung sowie digitale Teilhabe und digitale Kompetenzen der Initiativen stärken lassen, wie Kooperationen zwischen Kommunen und gemeinwohlorientierten Initiativen gefördert sowie die rechtlichen Rahmenbedingungen verbessert werden können und schließlich, wie sich Fördermaßnahmen stärker auf verschiedene Entwicklungsphasen der Initiativen ausrichten lassen. Die Broschüre ist ein Ergebnis des Forschungsprojekts "Umweltpolitische Unterstützungs- und Förderstrategien zur Stärkung sozial-ökologischer Formen von Zusammenleben und Gemeinwohlorientierung". Quelle: www.umweltbundesamt.de
description: Die Broschüre richtet sich an Akteure aus Zivilgesellschaft, Sozialunternehmen sowie (Umwelt-) Politik und -Verwaltung. Sie liefert Handlungsempfehlungen, wie gemeinwohlorientierte Initiativen (z. B. offene Werkstätten, Gemeinschaftsgärten, Online-Plattformen für Tausch und Verleih oder genossenschaftliche Wohnprojekte) unterstützt und ihr Beitrag für sozial-ökologische Transformationsprozesse gestärkt werden können. Die Handlungsansätze zeigen u.a., wie sich sozial-ökologische Wirkung sowie digitale Teilhabe und digitale Kompetenzen der Initiativen stärken lassen, wie Kooperationen zwischen Kommunen und gemeinwohlorientierten Initiativen gefördert sowie die rechtlichen Rahmenbedingungen verbessert werden können und schließlich, wie sich Fördermaßnahmen stärker auf verschiedene Entwicklungsphasen der Initiativen ausrichten lassen. Die Broschüre ist ein Ergebnis des Forschungsprojekts „Umweltpolitische Unterstützungs- und Förderstrategien zur Stärkung sozial-ökologischer Formen von Zusammenleben und Gemeinwohlorientierung“.
COF-MB4. TEA como sintomatología principal en Síndromes genéticos
Creators: name: Usuna Sosa, Estefanía Paula
name: Liaño Arriola, Cristina
name: Barana, José
name: Rodrigo Pérez, Ana Cristina
name: Ruiz Sanz, Francisco Carlos
name: Emeterio Delgado, Cristina
Publisher: name: Zenodo
Year: 2024

description: Por medio de este póster realizaremos una pequeña revisión de diferentes Sdr Genéticos atendidos en nuestro servicio de Psiquiatría Infanto Juvenil en los que el TEA representa la sintomatología central de los mismos; razón por la cual resulta de interés su conocimiento. Los síndromes valorados serán: Sdr. GEN CDK-13, Sdr. de microdeleción Loci 20Q13.33, Sdr. HECW2
title: El peritoneo, ese gran desconocido: anatomía y patología frecuente e infrecuente
Creators: name: Martínez González, Judith
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: Anatomy
subject: CT

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Recordar las claves anatómicas para el estudio e interpretación de la patología peritoneal. Mostrar mediante Tomografía Computerizada Multidetector (TCMD) un catálogo ilustrado de las diferentes patologías que pueden afectar al peritoneo,
con...
Supplementary document for Dynamically Tuned Arrays of Polariton Parametric Oscillators - 4897160.pdf
Creators: name: Kuznetsov, Alexander
name: Dagvadorj, Galbadrakh
name: Biermann, Klaus
name: Szymańska, Marzena
name: Santos, Paulo
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplement 1
Selection strategies for initial positions and initial velocities in multi-optima particle swarms
Creators: name: Chen, Stephen
name: Montgomery, James
Publisher: name: Swinburne
Year: 2024

description: Standard particle swarm optimization cannot guarantee convergence to the global optimum in multi-modal search spaces, so multiple swarms can be useful. The multiple swarms all need initial positions and initial velocities for their particles. Several simple strategies to select initial positions and initial velocities are presented. A series of experiments isolates the effects of these selected initial positions and velocities compared to random initial positions and velocities. A first set of experiments shows how locust swarms benefit from 'scouting' for initial positions and the use of initial velocities that 'launch away' from the previous optimum. A second set of experiments show that the performance of WoSP (Waves of Swarm Particles) can be improved by using new search strategies to select the initial positions and initial velocities for the particles in its sub-swarms.
Defining the Budding Yeast Chromatin Associated Interactome
Creators: name: Lambert, Jean-Philippe
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: subject: Chemistry, Biochemistry.

description: The identification of protein-protein as emerged as a powerful tool to characterize biological systems. In budding yeast in particular, systematic mapping of protein-protein interactions for most open reading frames drastically improve our understanding of this model organisms. Still, some classes of proteins, such as DNA binding proteins, remain poorly studied due to a lack of proper tools for their study. In this thesis, I describe the development of a novel affinity purification approach for the characterization of DNA binding proteins and of their associated proteins. The modified chromatin immunopurification (mChIP) approach consist of a single affinity purification step whereby chromatin-bound protein networks are isolated from mildly sonicated and gently clarified cellular extracts using magnetic beads coated with antibodies. The mChIP method was characterized in details demonstrating significant gain in sensitivity toward the determination of DNA binding protein interactome. Moreover, I showed that mChIP purification were successful for multiple class of proteins including numerous non-histone DNA binding proteins. Following the successful development of the mChIP method, I embarked on a large-scale characterization of chromatin associated proteins in budding yeast. In this way, 102 different DNA binding proteins were characterized by mChIP to determine their chromatin associated protein networks. This effort resulted in the detection of 3576 high confidence protein associations with 724 distinct preys. Approximately 75% of the baits had significantly improved interaction coverage using mChIP compared to the classical affinity purification methodologies. I also utilized the mChIP approach to perform targeted study of histone chaperones and unravel their interconnection. In summary, the mChIP method that I developed now makes it possible to systematically study chromatin associated proteins in budding yeast, breaking down a technical barrier that existed in the field of chromatin research for too long.
Supplementary document for Fabrication of spectrally sharp Si-based dielectric resonators: Combining etaloning with Mie resonances - 4897384.pdf
Creators: name: Abbarchi, Marco
name: toliopoulos, dimosthenhs
name: khoury, mario
name: bouabdellaoui, mohammed
name: Granchi, Nicoletta
name: claude, jean-benoit
name: benali, abdennacer
name: Berbezier, Isabelle
name: hannani, drisse
name: ronda, antoine
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplementary information
Supplementary document for Fabrication of spectrally sharp Si-based dielectric resonators: Combining etaloning with Mie resonances - 4897384.pdf
Creators: name: Abbarchi, Marco
name: toliopoulos, dimosthenhs
name: khoury, mario
name: bouabdellaoui, mohammed
name: Granchi, Nicoletta
name: claude, jean-benoit
name: benali, abdennacer
name: Berbezier, Isabelle
name: hannani, drisse
name: ronda, antoine
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: supplementary information
Current Advances in Seed Orchard Layouts : Two Case Studies in Conifers
Creators: name: Chaloupková, Kateřina
name: Stejskal, Jan
name: El-Kassaby, Yousry A.
name: Frampton, John
name: Lstibůrek, Milan
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Currently, there has been an increasing demand on seed orchard designs with respect to mitigating inbreeding in advanced generations or facing severe mortality at sites. Optimum Neighborhood Algorithm design (ONA) excels in solving these issues, as shown in two case studies. The first demonstrates the application of the ONA for populating empty positions in an existing orchard. Following this concept, the ONA can be used for upgrading existing orchards, where only high-value parents are retained and new parents are introduced, thus avoiding the genetic penalty associated with the establishment of new-generation seed orchards. The second illustrates benefits of combining the ONA with the Minimum Inbreeding (MI) seed orchard design. Utilizing the MI, distances among clonal rows of selected clones were maximized on the orchard grid while the remaining single-tree positions were populated by ONA.
An update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE)
Creators: name: Althof, Stanley E.
name: Mcmahon, Chris G.
name: Waldinger, Marcel D.
name: Serefoglu, Ege Can
name: Shindel, Alan W.
name: Adaikan, P. Ganesan
name: Becher, Edgardo
name: Dean, John
name: Giuliano, Francois
name: Hellstrom, Wayne J. G.
name: Giraldi, Annamaria
name: Glina, Sidney
name: Incrocci, Luca
name: Jannini, Emmanuele
name: McCabe, Marita
name: Parish, Sharon
name: Rowland, David
name: Segraves, R. Taylor
name: Sharlip, Ira
name: Torres, Luiz Otavio
Publisher: name: Swinburne
Year: 2024

description: Introduction: In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts. Aim: The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts. Method: A comprehensive literature review was performed. Results: This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients. Conclusion: Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years.
Diastatotropis arofaniana Tryzna & Banar 2022
Creators: name: Trýzna, Miloš
name: Kment, Petr
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Anthribidae
Diastatotropis
Diastatotropis arofaniana

description: (1) D. arofaniana Trýzna & Baňař, 2022.
TL: Tamatave prov.: Analamazaotra National Park
description: Published as part of Trýzna, Miloš & Kment, Petr, 2025, Diastatotropis elegans (Coleoptera: Anthribidae) from Madagascar: nomenclatural status, redescription and ecological notes, pp. 360-372 in Zootaxa 5627 (2) on page 369, DOI: 10.11646/zootaxa.5627.2.7, http://zenodo.org/record/15326085
Nutzen von Ressourcenverbrauch: Was uns Indikatoren zu Frieden, Entwicklung und zum ökologischen Fußabdruck verraten
Creators: name: Kalinowski, Martin B.
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 330 / Economics
subject: Sustainable development
subject: Ökologischer Fußabdruck
subject: Online-Publikation
subject: Ringvorlesung

description: Wie nachhaltig gehen wir mit unseren natürlichen Ressourcen um? Wie gerecht ist deren Verbrauch verteilt? In diesem Vortrag nähern wir uns einigen Antworten mithilfe von Daten, die den Ressourcenverbrauch von jedem Land messen bzw. anzeigen, welchen Nutzen die Länder erreicht haben. In Beispielen wird insbesondere auf den Energiesektor eingegangen. Durch die Korrelation von Daten wird vorgeführt, dass mit erhöhtem Ressourcenverbrauch der Entwicklungsstand, der Friedensstatus und die allgemeine Lebenszufriedenheit nicht unbegrenzt gesteigert werden. Gibt es ein Optimum? Kann und soll der Planet Erde zu einem optimalen Kosten-Nutzen-Verhältnis manövriert werden? Ist Nachhaltigkeit erreichbar, bei der für alle Menschen ein Existenzminimum gesichert wird, ohne dass die reichen Länder ihren Wohlstand einbüßen müssen? Diese Fragen können in diesem Vortrag nicht tiefgreifend beantwortet werden. Aber die Faktenlage besser einschätzen zu können, wird helfen, konstruktiv zur Erfindung von Lösungen und Wegen beizutragen.
Inflammatory immune reactivity to cereal proteins in type 1 diabetes
Creators: name: Lefebvre, David E
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Chemistry, Biochemistry.

description: Background. Type 1 diabetes (T1D) is an autoimmune disease in which a patient's immune system destroys the insulin-secreting beta-cells in the pancreas. The origin of beta-cell-specific leukocytes and the identity of the stimulatory antigens remain unknown. Disease development in individuals with genetic risk is thought to require environmental triggers. Epidemiological data and evidence from animal models suggests that exposure to dietary wheat can enhance diabetes autoimmunity. Some evidence suggests a crucial role of the gut barrier and gut-associated lymphoid tissues (GALT). Hypothesis . The gut in T1D susceptible rodents and patients is dysfunctional and characterized by a pro-inflammatory immune microenvironment which is associated with a loss of tolerance to cereal proteins. Methods. The inflammatory status of the GALT of diabetes-prone BioBreeding (BBdp) rats was quantified by RT-PCR, ELISA, and immunoblotting for T helper 1/T helper 2 (Th1/Th2) cytokine markers. T cell reactivity to wheat proteins was quantified by flow cytometric proliferation assay with cells from the GALT of BBdp rats and with peripheral blood mononuclear cells (PBMCs) from patients with type 1 diabetes. The effect of microbes and diet on diabetes outcome was characterized by feeding trials in germ-free BBdp rats. Results. T-bet/GATA-3 transcription factor expression ratio reflected Th1/Th2 immune cell status in the BB rat and provided a snapshot of the in vivo inflammatory status of tissues. At an age which pre-dates the development of T 1D, the GALT of BBdp rats, fed a diabetes-promoting cereal-based diet, contained an unusually high proportion of pro-inflammatory Th1 cells. These T cells specifically responded to wheat proteins in vitro. Similarly, T cell reactivity to wheat proteins was also observed in PBMCs in a subset of patients with T1D. PBMCs from a patient with T1D and celiac disease-associated gut damage revealed strong Th1-biased immune reactivity to wheat protein. Diabetes was promoted by a cereal-based diet in both the presence and absence of microbes in BBdp rats, and a diabetes-promoting effect of microbes was revealed in the absence of cereal proteins. Conclusions. At ages which precede diabetes, a pro-inflammatory state in the gut and GALT of BBdp rats is associated with the activation of wheat-specific T cells. An immune response to wheat is also present in PBMCs in a subset of patients with T1D. A low-antigen diet inhibited the development of diabetes in BBdp rats and almost completely prevented diabetes in germ-free BBdp rats. These findings suggest that the gut could play an important role in the development of T1D.
Expand into 2013 by toasting 100 years of modern cosmology
Creators: name: Mackie, Glen
Publisher: name: Swinburne
Year: 2024

description: As 2012 comes to a close and you toast the New Year, be sure to also raise a glass to one Vesto Melvin Slipher. My intent is to describe what Slipher did 100 years ago in Flagstaff, Arizona and why this event can be regarded as the birth of modern cosmology.
D1.3 - Framework for activities criteria
Creators: name: Dongo, Dario
name: Adelmo Della Penna, Andrea
name: Astley, Sian
name: de Novo Barros, Ana
name: Campos, Joana
Publisher: name: Zenodo
Year: 2024

description: The purpose of this deliverable (D), D1.3 - Framework for activities criteria, is to define the criteria for the WASTELESS Public Blockchain, the documents and codification of Food Loss and Waste (FLW) materials. The policy and regulatory aspects related to blockchain, and FLWs, will be used by partners in Work Package (WP) 1(Transversal community of practice and framework for measurement and monitoring of FLW) to provide a mapping of existing aspects at European Union (EU)level (or individual Member States (MSs), where appropriate) and recommendations to foster use of blockchain and other Distributed Ledger Technologies (DLTs) in the measurement, quantification and management of FLWs.
thesis S2 Yuliar
Creators: name: Yuliar Firdaus
Publisher: name: figshare
Year: 2020
Subjects: subject: 20504 Photonics, Optoelectronics and Optical Communications
subject: FOS: Physical sciences

description: In this thesis, the interaction of light with matter inside the metallic rectangular waveguide which cover the spontaneous emission and resonance energy transfer are investigated
using Green’s tensor approach. The preferred approach is to obtain the emission rate and energy transfer rate via Green’s tensor. It has been found that the emission rate
and energy transfer rate depends upon three factors: the cross-section size of waveguide, position of molecule with respect to the interface, and index-contrast.
High conservation of tetanus and botulinum neurotoxins cleavage sites on human SNARE proteins suggests that these pathogens exerted little or no evolutionary pressure on humans
Creators: name: Carle, Stefan
name: Pirazzini, Marco
name: Rossetto, Ornella
name: Barth, Holger
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: ExAC
subject: gnomAD
subject: botulinum neurotoxin
subject: tetanus neurotoxin
subject: SNAP-25
subject: VAMP-1
subject: syntaxin-1A
subject: DDC 610 / Medicine & health
subject: Botulinum toxins
subject: Neurotoxins
subject: SNARE proteins
subject: Syntaxin 1
subject: Botulinustoxin
subject: Nervengift
subject: Syntaxine

description: The Genome Aggregation Database presently contains >120,000 human genomes. We searched in this database for the presence of mutations at the sites of tetanus (TeNT) and botulinum neurotoxins (BoNTs) cleavages of the three SNARE proteins: VAMP, SNAP-25 and Syntaxin. These mutations could account for some of the BoNT/A resistant patients. At the same time, this approach was aimed at testing the possibility that TeNT and BoNT may have acted as selective agents in the development of resistance to tetanus or botulism. We found that mutations of the SNARE proteins are very rare and concentrated outside the SNARE motif required for the formation of the SNARE complex involved in neuroexocytosis. No changes were found at the BoNT cleavage sites of VAMP and syntaxins and only one very rare mutation was found in the essential C-terminus region of SNAP-25, where Arg198 was replaced with a Cys residue. This is the P1’ cleavage site for BoNT/A and the P1 cleavage site for BoNT/C. We found that the Arg198Cys mutation renders SNAP-25 resistant to BoNT/A. Nonetheless, its low frequency (1.8 × 10−5) indicates that mutations of SNAP-25 at the BoNT/A cleavage site are unlikely to account for the existence of BoNT/A resistant patients. More in general, the present findings indicate that tetanus and botulinum neurotoxins have not acted as selective agents during human evolution as it appears to have been the case for tetanus in rats and chicken.
Abhängigkeit der RCG-Simulationen von unterschiedlichen meteorologischen Treibern
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2013
Subjects: subject: Feinstaub
subject: Luftreinhaltemaßnahme
subject: Luftbelastung
subject: Luft
subject: Air

description: Um den Einfluss der Meteorologie auf die Berechnung von Luftschadstoffkonzentrationen quantitativ erfassen zu können, wird in dieser Studie ein Chemisches Transport-Modell (CTM) benutzt, und dieses mit zwei unterschiedlichen Meteorologien laufen gelassen.
Quelle: www.umweltbundesamt.de
description: Um den Einfluss der Meteorologie auf die Berechnung von Luftschadstoffkonzentrationen quantitativ erfassen zu können, wird in dieser Studie ein Chemisches Transport-Modell (CTM) benutzt, und dieses mit zwei unterschiedlichen Meteorologien laufen gelassen.
Diastatotropis blazeji Tryzna 2019
Creators: name: Trýzna, Miloš
name: Kment, Petr
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Anthribidae
Diastatotropis
Diastatotropis blazeji

description: (2) D. blazeji Trýzna, 2019 in Trýzna & Andrianomenjanahary (2019).
TL: Toamasina prov.: Ambohitsitondrona
description: Published as part of Trýzna, Miloš & Kment, Petr, 2025, Diastatotropis elegans (Coleoptera: Anthribidae) from Madagascar: nomenclatural status, redescription and ecological notes, pp. 360-372 in Zootaxa 5627 (2) on page 369, DOI: 10.11646/zootaxa.5627.2.7, http://zenodo.org/record/15326085
Genetic variability and protein-protein interactions of puroindolines in relation to wheat grain texture and antimicrobial properties
Creators: name: Ramalingam, Abirami
Publisher: name: Swinburne
Year: 2024

description: The puroindoline genes, Pina-D1 and Pinb-D1, have been shown to be linked to grain hardness, an important trait in the end-use quality of wheat and hence in international usage and trade of wheat. Variations, in either or both genes, or lack of expression of either gene, result in a hard texture of common wheat, while the durum wheat that lacks both Pin genes is extremely hard. Depending on the type of mutation, a range of hardness observed. There has been a great interest to search for further genetic variations in these genes, firstly, to understand better the way these genes affect grain texture, and secondly, to introduce new variations into breeding programs in order to improve the end-use quality of wheat. Landraces of wheat, particularly from China (the secondary centre of origin of wheat), were analyzed and a new Pina-D1 allele was discovered, in addition to confirmation of several other reported alleles. Scanning electron microscopy analysis of various wheats with differences in their Pin alleles, showed more attachment between starch and protein matrix for those wheats either lacking Pins, or with potential truncation in either PIN, in comparison to the wheat with a single amino acid substitution in the Pin allele. Analysis of the Pinb-2 genes showed that these comprised a multigene family and were greatly diverse. Many new haplotypes were identified in hexaploid, tetraploid and dipoid wheats, including a new group designated Pinb-2v6. Synthetic peptides, designed based on the truncated tryptophan rich domain (TRD) of the putative PINB-2 proteins, comprising of only two Trps, showed antibacterial and antifungal activity, suggesting that the PINB-2 proteins could be of importance in seed defense, as suggested for the PINs. Many studies have suggested that the PIN proteins (PINA and PINB) were interdependent and interact to confer the grain softness trait. Examination of this aspect using the yeast two-hybrid system showed that PINA and PINB did interact physically, thus shedding some light on their possible function and supporting suggestions that they co-operatively bind to lipids. PINA was also able to interact with itself, which may be relevant to more number of Trps present at the TRD in comparison to PINB and GSP-1 which may have some association to its suggested ability to aggregate at the lipid membrane. The observed interactions of GSP-1 with PINA or PINB, suggest that the GSP-1 could be a minor factor influencing grain hardness.
Social Determinants of Rural Health Workforce Retention: A Scoping Review
Creators: name: Cosgrave, Catherine
name: Malatzky, Christina
name: Gillespie, Judy
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Residents of rural and remote Australia have poorer health outcomes than their metropolitan counterparts. A major contributor to these health disparities is chronic and severe health workforce shortages outside of metropolitan areas—a global phenomenon. Despite emerging recognition of the important influence of place-based social processes on retention, much of the political attention and research is directed elsewhere. A structured scoping review was undertaken to describe the range of research addressing the influence of place-based social processes on turnover or retention of rural health professionals, to identify current gaps in the literature, and to formulate a guide for future rural health workforce retention research. A systematic search of the literature was performed. In total, 21 articles were included, and a thematic analysis was undertaken. The themes identified were (1) rural familiarity and/or interest, (2) social connection and place integration, (3) community participation and satisfaction, and (4) fulfillment of life aspirations. Findings suggest place-based social processes affect and influence the retention of rural health workforces. However, these processes are not well understood. Thus, research is urgently needed to build robust understandings of the social determinants of rural workforce retention. It is contended that future research needs to identify which place-based social processes are amenable to change.
The International Society for the Study of Women's Sexual Health process of care for management of hypoactive sexual desire disorder in women
Creators: name: Clayton, Anita H.
name: Goldstein, Irwin
name: Kim, Noel N.
name: Althof, Stanley E.
name: Faubion, Stephanie S.
name: Faught, Brooke M.
name: Parish, Sharon J.
name: Simon, James A.
name: Vignozzi, Linda
name: Christiansen, Kristin
name: Davis, Susan R.
name: Freedman, Murray A.
name: Kingsberg, Sheryl A.
name: Kirana, Paraskevi-Sofia
name: Larkin, Lisa
name: McCabe, Marita
name: Sadovsky, Richard
Publisher: name: Swinburne
Year: 2024

description: The International Society for the Study of Women's Sexual Health process of care (POC) for management of hypoactive sexual desire disorder (HSDD) algorithm was developed to provide evidence-based guidelines for diagnosis and treatment of HSDD in women by health care professionals. Affecting 10% of adult females, HSDD is associated with negative emotional and psychological states and medical conditions including depression. The algorithm was developed using a modified Delphi method to reach consensus among the 17 international panelists representing multiple disciplines. The POC starts with the health care professional asking about sexual concerns, focusing on issues related to low sexual desire/interest. Diagnosis includes distinguishing between generalized acquired HSDD and other forms of low sexual interest. Biopsychosocial assessment of potentially modifiable factors facilitates initiation of treatment with education, modification of potentially modifiable factors, and, if needed, additional therapeutic intervention: sex therapy, central nervous system agents, and hormonal therapy, guided in part by menopausal status. Sex therapy includes behavior therapy, cognitive behavior therapy, and mindfulness. The only central nervous system agent currently approved by the US Food and Drug Administration (FDA) for HSDD is flibanserin in premenopausal women; use of flibanserin in postmenopausal women with HSDD is supported by data but is not FDA approved. Hormonal therapy includes off-label use of testosterone in postmenopausal women with HSDD, which is supported by data but not FDA approved. The POC incorporates monitoring the progress of therapy. In conclusion, the International Society for the Study of Women's Sexual Health POC for the management of women with HSDD provides a rational, evidence-based guideline for health care professionals to manage patients with appropriate assessments and individualized treatments.
D1.2 - Report on improved framework for FLW  measurement & monitoring
Creators: name: Zhuang, Qian
name: Wu, Chen
name: Ezgi, Doğan
name: Carole, Liechti
name: Adelmo Della Penna, Andrea
name: Finglas, Paul
name: de Novo Barros, Ana
name: Campos, Joana
Publisher: name: Zenodo
Year: 2024

description: Specifically, this deliverable aims to provide recommendations on the FLW measurement and monitoring framework harmonization and enriched with barriers and solutions identification. To achieve these objectives, a three-round of literature were conducted to better understand the research status and inform framework development. An expert consultation with online survey was carried out to include expert’s insight in framework key elements, drivers, barriers, and solutions identifications.
Diastatotropis clavigera Frieser 1992
Creators: name: Trýzna, Miloš
name: Kment, Petr
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Anthribidae
Diastatotropis
Diastatotropis clavigera

description: (3) D. clavigera Frieser, 1992.
TL: Madagascar
description: Published as part of Trýzna, Miloš & Kment, Petr, 2025, Diastatotropis elegans (Coleoptera: Anthribidae) from Madagascar: nomenclatural status, redescription and ecological notes, pp. 360-372 in Zootaxa 5627 (2) on page 369, DOI: 10.11646/zootaxa.5627.2.7, http://zenodo.org/record/15326085
title: Key Issues in Rural Development: A University Graduate Course
Creators: name: Meassick, Mark A.
Publisher: name: University of Massachusetts Amherst
Year: 1987
Subjects: subject: Education

description: A graduate course on rural development issues is presented that focuses primarily on the processes involved in development both at a personal and abstract leve. A theoretical foundation for the course is outlined based on David Kolb's theory of experiential learning. This model is transcribed into learning environments necessary to focus participant awareness of issues surrounding their own learning style. The role of the facilitator who demands attention to learning style as well as content in rural development is defined, utilizing Malcolm Knowles' andragogical concepts. Finally the course curriculum is presented, followed by lesson plans and readings supplemental to the text books.
The periodontal pathogen, Porphyromonas gingivalis , and the participatory role of caspase-1 in the progression of atherosclerosis
Creators: name: Gage, Jessica
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Molecular.
subject: Health Sciences, Dentistry.

description: Porphyromonas gingivalis, a key pathogen in periodontal disease, promotes atherosclerosis in apolipoprotein E null (apoe-/-) mice, a well characterized mouse model of the disease. Previous studies have provided indirect evidence that P gingivalis is capable of activating the enzyme caspase-1 in vitro, while preliminary studies conducted by our laboratory have outlined a role for caspase-1 in atherosclerosis in apoe-/- mice. The present study provides direct evidence that P gingivalis is capable of activating caspase-1, and that P gingivalis is capable of gaining access to, and localizing at, sites of lesion development following an oral challenge. Oral infection with P gingivalis exacerbated the development of atherosclerosis in the aortic root of male mice competent for caspase-1 as compared to those deficient in the enzyme. Infected animals also displayed evidence of alveolar bone loss, a hallmark of periodontal disease. Our findings reveal that oral infection with P gingivalis accelerates atherosclerotic lesion development in male apoe-/- mice through the activation of caspase-1.
Profiling 'Threshold 9': Using Big History as a framework for thinking about the contours of the coming global future
Creators: name: Voros, Joseph
Publisher: name: Swinburne
Year: 2024

description: Big History provides a very powerful framework for understanding the broad contours of the past, from the beginning of the Universe at the Big Bang to our present globe-spanning information-based technological civilization. But to what degree can this framework also be used to draw potential insights into the contours of the possible future of humanity, as it emerges from the complex dynamics of the present? In this paper, we make use of the '8-threshold' formulation of Big History due to David Christian and examine some of the conceptual possibilities that arise when we consciously and systematically take a 'Big History perspective' on the future of humanity at the global scale. Specifically, we consider the question of what the next major threshold in Big History---what we might therefore call 'Threshold 9'---may look like in broad outline. We find that, of the four main 'generic' categories of possible futures, the most probable global future currently in prospect---barring a major catastrophic shock, technological energy breakthrough, or similar low-probability 'wildcard' event---is a slowly-unfolding collapse or 'descent' over a time-scale of decades-to-centuries towards a human society characterized by ever-declining access to sources of fossil-fuel-based energy. Such a future trajectory clearly has major implications for the level of human societal complexity possible. This suggests undertaking an anticipatory program of continuing research and exploration into both the underlying nature and the emergent characteristics of the coming transition to 'Threshold 9'.
CNC tool path generation for finish milling convex pockets.
Creators: name: Manuel, Deepak.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Engineering, Mechanical.

description: Production efficiency has increased considerably due to the use of computer-numerical controlled (CNC) machines. To machine a component on a CNC machine, part programs which define the cutting tool path are needed. This tool path is usually planned from computer-aided design (CAD) drawings, and converted to a computer-aided manufacturing (CAM) machine input format. However, several production bottlenecks are encountered in this transformation process, leading to escalated production costs and time. This problem can be attributed to two major causes. The first issue is the mode by which the CAD data is converted into CAM data and the second one is the efficiency or optimality of the physical process itself in producing an error-free machined surface. Considering these drawbacks, an automatic tool path generating system to machine 2 1/2 dimensional arbitrarily shaped convex pockets was developed, in which tool path planning is done without the aid of CAD modellers or data exchange formats. This proposed methodology generates a spiral-like tool path by dynamically computing optimal offsets of the pocket boundary contour based on the type and size of the milling cutter, the geometry of the pocket contour and surface finish tolerance requirements. This part programming system is PC based and simultaneously generates a G-code file, a verification file for simulating the generated tool path on a CAD package and a result file for research purposes.
Diastatotropis crassicornis Waterhouse 1882
Creators: name: Trýzna, Miloš
name: Kment, Petr
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Anthribidae
Diastatotropis
Diastatotropis crassicornis

description: (4) D. crassicornis Waterhouse, 1882.
TL: Madagascar
description: Published as part of Trýzna, Miloš & Kment, Petr, 2025, Diastatotropis elegans (Coleoptera: Anthribidae) from Madagascar: nomenclatural status, redescription and ecological notes, pp. 360-372 in Zootaxa 5627 (2) on page 369, DOI: 10.11646/zootaxa.5627.2.7, http://zenodo.org/record/15326085
A score based on NfL and glial markers may differentiate between relapsing–remitting and progressive MS course
Creators: name: Huss, André
name: Otto, Markus
name: Senel, Makbule
name: Ludolph, Albert C.
name: Abdelhak, Ahmed
name: Tumani, Hayrettin
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: CSF
subject: glial markers
subject: neurofilament light chain
subject: progressive MS
subject: DDC 610 / Medicine & health
subject: Multiple sclerosis
subject: Biomarkers
subject: Cerebrospinal fluid
subject: Serum
subject: Neuroglia
subject: Multiple Sklerose
subject: Biomarker
subject: Neurofilament

description: Background: The diagnostic use of biomarkers in body fluids of multiple sclerosis (MS) patients allows the monitoring of different pathophysiological aspects of the disease. We previously reported elevated cerebrospinal fluid (CSF) and serum levels of glial fibrillary acidic protein (GFAP) but not neurofilament light chain (NfL) in progressive (PMS) compared to relapsing–remitting MS (RRMS) patients. Objectives: We analyzed the glial marker chitinase-3-like protein 1 (CHI3L1) in the CSF and serum of PMS and RRMS patients. To capture the extent of glial processes in relation to axonal damage in each individual patient, we established a score based on CHI3L1, GFAP, and NfL and compared this score between RRMS and PMS patients and its association with the extended disability status scale (EDSS). Methods: For this retrospective study, we included 86 MS patients (47 RRMS and 39 PMS) and 20 patients with other non-inflammatory neurological diseases (OND) as controls. NfL and GFAP levels were determined by the single-molecule array (Simoa). CHI3L1 levels were measured with classical enzyme-linked immunosorbent assay. A score was calculated based on glial to axonal markers (CHI3L1*GFAP/NfL, referred to as “Glia score”). Results: CHI3L1 showed higher CSF levels in PMS vs. RRMS and controls (p < 0.001 and p < 0.0001, respectively), RMS vs. controls (p < 0.01), and higher serum levels for PMS vs. RRMS (p < 0.05). The Glia score was higher in the CSF of PMS compared to RRMS patients (p < 0.0001) and in the serum of PMS patients compared to RRMS (p < 0.01). Furthermore, the Glia score and CHI3L1 in serum but not in CSF correlated with the disability as determined by EDSS in the PMS group but not in the RRMS group (Spearman ρ = 0.46 and 0.45, p = 0.003 and 0.004, respectively). Discussion: Our data indicate the involvement of glial mechanisms during the pathogenesis of PMS. Moreover, a calculated score may help to differentiate between PMS and RMS in the CSF and monitor disease progression in the serum of PMS patients.
Production of phytase and reduction of phytic acid content in canola meal by solid state fermentation.
Creators: name: Ebune, Anne Ebane.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Engineering, Chemical.

description: A static state technique for fermentation was applied using Aspergillus ficuum NRRL 3135 on canola meal for the production of phytase and for the reduction of the phytic acid content in the meal. Aspergillus ficuum was chosen as a result of its high phytase producing capacity. In the study of the effects of physical and nutritional factors on the enzyme production and the phytic acid content reduction, it was found that moisture content was a critical factor and 64% water in the medium was found to be the optimum moisture content for both enzyme production and phytic acid content reduction. Increasing time of homogenization of inoculum up to 240 seconds improved enzyme production and phytic acid reduction. Increase in both inoculum concentration (biomass) and inoculum age up to 7-days old increased enzyme production and rate of phytic acid content reduction. With increase in initial pH of medium of up to 5.7, increased enzyme production and rate of phytic acid reduction were achieved. In the addition of surfactants to medium, sodium oleate was found to significantly increase enzyme production and the rate of phytic acid content reduction while Triton X-100 gave a negative effect. The addition of 1 mg phosphate remarkably increased the enzyme production and phytic acid content reduction; though a negative effect was obtained for systems containing combined portions of oleate and phosphate. Biomass in the solid culture was found to increase during fermentation up to 144 h of incubation and the protein content of culture also increased to about 18% after 96 h of incubation; hence this method of fermentation could be used to improve the nutritional quality of the meal for animal feed.