cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Absence of non-canonical, inhibitory MYD88 splice variants in B cell lymphomas correlates with sustained NF-κB signaling
Creators: name: Cardona Gloria, Yamel
name: Bernhart, Stephan H.
name: Fillinger, Sven
name: Wolz, Olaf-Oliver
name: Dickhöfer, Sabine
name: Admard, Jakob
name: Ossowski, Stephan
name: Nahnsen, Sven
name: Siebert, Reiner
name: Weber, Alexander N. R.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: MYD88
subject: TLR - Toll-like receptor
subject: negative feedback loop
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Myeloid Differentiation Factor 88
subject: Lymphoma, B-cell
subject: Lymphoma, Large B-cell, Diffuse
subject: NF-kappa B
subject: Toll-Like Receptors
subject: Alternative Splicing
subject: B-Zell-Lymphom
subject: Nuklearfaktor Kappa B

description: Gain-of-function mutations of the TLR adaptor and oncoprotein MyD88 drive B cell lymphomagenesis via sustained NF-κB activation. In myeloid cells, both short and sustained TLR activation and NF-κB activation lead to the induction of inhibitory MYD88 splice variants that restrain prolonged NF-κB activation. We therefore sought to investigate whether such a negative feedback loop exists in B cells. Analyzing MYD88 splice variants in normal B cells and different primary B cell malignancies, we observed that MYD88 splice variants in transformed B cells are dominated by the canonical, strongly NF-κB-activating isoform of MYD88 and contain at least three novel, so far uncharacterized signaling-competent splice isoforms. Sustained TLR stimulation in B cells unexpectedly reinforces splicing of NF-κB-promoting, canonical isoforms rather than the ‘MyD88s’, a negative regulatory isoform reported to be typically induced by TLRs in myeloid cells. This suggests that an essential negative feedback loop restricting TLR signaling in myeloid cells at the level of alternative splicing, is missing in B cells when they undergo proliferation, rendering B cells vulnerable to sustained NF-κB activation and eventual lymphomagenesis. Our results uncover MYD88 alternative splicing as an unappreciated promoter of B cell lymphomagenesis and provide a rationale why oncogenic MYD88 mutations are exclusively found in B cells.
MOESM1 of A multivariate analysis with direct additive and inbreeding depression load effects
Creators: name: Varona, Luis
name: Altarriba, Juan
name: Moreno, Carlos
name: Martínez-Castillero, María
name: Casellas, Joaquim
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1: Figure S1. Plot of the Gibbs Sampler chains for the inbreeding load variance in the Pirenaica Breed.
title: Wychowawcza funkcja Policji. Perspektywa polska
Creators: name: Magda, Ernest
Publisher: name: EDUsfera. Ewa Jurczyk-Romanowska
Year: 2020

description: Artykuł stanowi próbę wykazania, że obok klasycznych funkcji Policji takich, jak funkcja prewencyjna i funkcja represyjna dynamicznie rozwija się nowa funkcja – wychowawcza. Zmiany społeczno-polityczne w Polsce po roku 1989 spowodowały odrodzenie się formacji policyjnej, gdzie kluczowe znaczenie miała zmiana wizerunku policjanta w percepcji społecznej i oczekiwania, że Policja na nowo zdefiniuje swoją misję w duchu idei Community Policing na rzecz działań proaktywnych w środowisku lokalnym. W artykule wskazano na podstawy prawne umożliwiające rozwój działalności pedagogicznej policjantów demaskując przy tym przeszkody organizacyjne i mentalne, które tę działalność utrudniają. Rekomendacje do praktyki wprowadzone w końcowej części opracowania mogą stanowić wskazówkę jak skutecznej kształtować kulturę pedagogiczną policjantów.
SafeSpace Chat
Creators: name: Lowrance, Chanda Mandisa
Publisher: name: Zenodo
Year: 2025

description: SafeSpace Chat is an AI-powered chatbot platform designed specifically for the LGBTQ+ community. The mission of SafeSpace Chat is to provide a safe, inclusive, and supportive digital space where individuals within the LGBTQ+ community can connect, share experiences, and access resources that promote mental health and wellness. By harnessing cutting-edge technology and a deep understanding of the unique needs of this diverse community, SafeSpace Chat fosters meaningful interactions, inspires self-growth, and empowers its users. For more information and updates, please visit https://safespacechat.neocities.org/.
On a Conjecture of Lovász on Circle-Representations of Simple 4-Regular Planar Graphs
Creators: name: Bekos, Michael A.
name: Raftopoulou, Chrysanthi N.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: Lovász conjectured that every connected 4-regular planar graph G admits a realization as a system of circles, i.e., it can be drawn on the plane utilizing a set of circles, such that the vertices of G correspond to the intersection and touching points of the circles and the edges of G are the arc segments among pairs of intersection and touching points of the circles. In this paper, we settle this conjecture. In particular, (a) we first provide tight upper and lower bounds on the number of circles needed in a realization of any simple 4-regular planar graph, (b) we affirmatively answer Lovász's conjecture, if G is 3-connected, and (c) we demonstrate an infinite class of simple connected 4-regular planar graphs which are not 3-connected (i.e., either simply connected or biconnected) and do not admit realizations as a system of circles.
Bounds on localisable information via semidefinite programming
Creators: name: Synak, Barbara
name: Horodecki, Karol
name: Horodecki, Michal
Publisher: name: arXiv
Year: 2004
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate so-called localisable information of bipartite states and a parallel notion of information deficit. Localisable information is defined as the amount of information that can be concentrated by means of classical communication and local operations where only maximally mixed states can be added for free. The information deficit is defined as difference between total information contents of the state and localisable information. We consider a larger class of operations: the so called PPT operations, which in addition preserve maximally mixed state (PPT-PMM operations). We formulate the related optimization problem as sedmidefnite program with suitable constraints. We then provide bound for fidelity of transition of a given state into product pure state on Hilbert space of dimension d. This allows to obtain general upper bound for localisable information (and also for information deficit). We calculated the bounds exactly for Werner states and isotropic states in any dimension. Surprisingly it turns out that related bounds for information deficit are equal to relative entropy of entanglement (in the case of Werner states - regularized one). We compare the upper bounds with lower bounds based on simple protocol of localisation of information.
description: 14 pages, revtex
Evidence for an intermediate mass black hole and a multi-zone warm absorber in NGC 4395
Creators: name: Shih, D. C.
name: Iwasawa, K.
name: Fabian, A. C.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report on the results of an analysis in the X-ray band of a recent long ASCA observation of NGC 4395, the most variable low-luminosity AGN known. A relativistically-broadened iron line at ~6.4 keV is clearly resolved in the time-averaged spectrum, with an equivalent width of 310^{+70}_{-90} eV. Time-resolved spectral analysis of the heavily absorbed soft X-ray band confirms the existence of a variable, multi-zone warm absorber in this source, as proposed in a previous analysis of a shorter ASCA observation. The light curve of the source is wildly variable on timescales of hours or less, and a factor of nearly 10 change in count-rate was recorded in a period of less than 2000 s. The long observation and variability of the source allowed the power density spectrum (PDS) to be constructed to an unprecedented level of detail. There is evidence for a break in the PDS from a slope of α~1 to α~1.8 at a frequency of around 3 \times 10^{-4} Hz. The central black hole mass of NGC 4395 is estimated to be approximately 10^4-10^5 solar masses using the break in the PDS, a result consistent with previous analyses using optical and kinematical techniques.
description: 8 pages, 6 figures, accepted for publication in MNRAS
The Cost of Segregation in Social Networks
Creators: name: Allouch, Nizar
name: Allouch, Nizar
Publisher: name: Unknown
Year: 2013
Subjects: subject: Public Economics
subject: Public Goods
subject: Segregated Society
subject: Private Provision
subject: Networks
subject: Bonacich Transfer Index

description: This paper investigates the private provision of public goods in segregated societies. While most research agrees that segregation undermines public provision, the findings are mixed for private provision: social interactions, being strong within groups and limited across groups, may either increase or impede voluntary contributions. Moreover, although efficiency concerns generally provide a rationale for government intervention, surprisingly, little light is shed in the literature on the potential effectiveness of such intervention in a segregated society. This paper first develops an index based on social interactions, which, roughly speaking, measures the welfare impact of income redistribution in an arbitrary society. It then shows that the proposed index vanishes when applied to large segregated societies, which suggests an “asymptotic neutrality” of redistributive policies.
Novel approach to the study of quantum effects in the early universe
Creators: name: Geralico, A.
name: Landolfi, G.
name: Ruggeri, G.
name: Soliani, G.
Publisher: name: arXiv
Year: 2003
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We develop a theoretical frame for the study of classical and quantum gravitational waves based on the properties of a nonlinear ordinary differential equation for a function $σ(η)$ of the conformal time $η$, called the auxiliary field equation. At the classical level, $σ(η)$ can be expressed by means of two independent solutions of the ''master equation'' to which the perturbed Einstein equations for the gravitational waves can be reduced. At the quantum level, all the significant physical quantities can be formulated using Bogolubov transformations and the operator quadratic Hamiltonian corresponding to the classical version of a damped parametrically excited oscillator where the varying mass is replaced by the square cosmological scale factor $a^{2}(η)$. A quantum approach to the generation of gravitational waves is proposed on the grounds of the previous $η-$dependent Hamiltonian. An estimate in terms of $σ(η)$ and $a(η)$ of the destruction of quantum coherence due to the gravitational evolution and an exact expression for the phase of a gravitational wave corresponding to any value of $η$ are also obtained. We conclude by discussing a few applications to quasi-de Sitter and standard de Sitter scenarios.
description: 20 pages, to appear on PRD. Already published background material has been either settled up in a more compact form or eliminated
MOESM1 of Towards standardization of absolute SPECT/CT quantification: a multi-center and multi-vendor phantom study
Creators: name: Peters, Steffie
name: Werf, Niels
name: Segbers, Marcel
name: Velden, Floris
name: Wierts, Roel
name: Blokland, Koos
name: Konijnenberg, Mark
name: Lazarenko, Sergiy
name: Visser, Eric
name: Gotthardt, Martin
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Settings of low dose CT protocols used for attenuation correction. Table S2. Cross-calibration protocols for dose calibrators to SPECT/CT system according to vendor recommendations.
Experimental characterization of the energetics of quantum logic gates
Creators: name: Cimini, Valeria
name: Gherardini, Stefano
name: Barbieri, Marco
name: Gianani, Ilaria
name: Sbroscia, Marco
name: Buffoni, Lorenzo
name: Paternostro, Mauro
name: Caruso, Filippo
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We characterize the energetic footprint of a two-qubit quantum gate from the perspective of non-equilibrium quantum thermodynamics. We experimentally reconstruct the statistics of energy and entropy fluctuations following the implementation of a controlled-unitary gate, linking them to the performance of the gate itself and the phenomenology of Landauer principle at the single-quantum level. Our work thus addresses the energetic cost of operating quantum circuits, a problem that is crucial for the grounding of the upcoming quantum technologies.
description: This version matches the published article
Prodilis kristine Gordon and Hanley 2017, new species
Creators: name: Gordon, Robert D.
name: Hanley, Guy A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Coccinellidae
Prodilis
Prodilis kristine

description: 23. Prodilis kristine Gordon and Hanley, new species
 Neaporia indagator: Gorham, 1897: 218.
 Description. Male holotype. Length 2.0 mm, width 1.6 mm; body oval, elytron with side rounded, wider than pronotal base, widest before middle of elytra. Dorsal surface entirely shiny without trace of microsculpture. Color bluish black (Fig. 447); head yellow except vertex black (Fig. 448); pronotum bluish black except anterolateral 1/4 yellow; antenna, mouthparts, legs, prosternum yellow; epipleuron yellowish red; venter dark yellowish brown; abdomen yellowish brown basally and medially, laterally and apically yellow. Head punctures large, separated by a diameter or less; pronotal punctures slightly smaller than on head, separated by a diameter or less; elytral punctures larger than on pronotum, separated by less than a diameter; prosternal, mesosternal punctures large, separated by a diameter or less; metasternum with basal and lateral punctures as large as on mesosternum, median punctures large, widely separated; abdomen with punctures on ventrites 1–3 large, separated by 1 to 3 times a diameter, punctures on remaining ventrites smaller, separated by about a diameter. Head with frons wide, parallel sided, nearly twice width of eye measured at vertex; eye canthus short; apical maxillary palpomere short, widened from base to apex. Pronotum widest at middle, reflexed lateral margin narrow, equal in width from base to apex. Epipleuron descending externally, as wide as pronotal hypomeron. Prosternum as wide as long, longer than mesosternum, base truncate, lateral carina wide, short, extended to apex of coxa. Postcoxal line on ventrite 1 short, rounded, extended to middle of ventrite. Apex of ventrite 5 very slightly emarginate. Genitalia with basal lobe about as long as paramere, slender, sides weakly narrowed from base to deeply emarginate apex; paramere slender, narrowed from base to rounded apex (Fig. 449, 450); sipho short, robust, with complex apex (Fig. 451).
 Female. Unknown.
 Variation. Unknown.
 Type material. Holotype male; PANAMA: Bugaba, Panam, Champion, N. indagator, var?(handwritten), B.C.A., Col., VII. (BMNH).
 Remarks. Gorham (1897) considered this specimen a variety of Neaporia indagator. It is distinguished from other Prodilis species by a combination of pronotum with lateral 1/4 yellow, bluish black elytron, yellow prosternum, and structure of the male genitalia.
description: Published as part of Gordon, Robert D. & Hanley, Guy A., 2017, South American Coccinellidae (Coleoptera), Part XVII: systematic revision of Western Hemisphere Cephaloscymnini (Coccinellinae) with description of a cryptic new genus and species of Coccidulini (Coccinellinae), pp. 1-158 in Insecta Mundi 2017 (601) on pages 73-74, DOI: 10.5281/zenodo.5170031
Additional file 9 of Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex
Creators: name: Aydin, Dorothee
name: Filippov, Mikhail A
name: Jakob-Andreas Tschäpe
name: Gretz, Norbert
name: Prinz, Marco
name: Eils, Roland
name: Brors, Benedikt
name: Müller, Ulrike C
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Authors’ original file for figure 2
(phi -> K K) decay in light cone QCD
Creators: name: Aliev, T. M.
name: Kanik, I.
name: Savci, M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The coupling constant of (phi -> K K) decay is calculated in light cone QCD sum rules. The result obtained for g_{phi KK} = (4.9 pm 0.8) is in a good agreement with the existing experimental result.
description: 9 pages, 2 figures, LaTeX formatted
MOESM3 of Correction to: Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations
Creators: name: Shailima Rampogu
name: Ayoung Baek
name: Zeb, Amir
name: Lee, Keun
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Additional file 9. Active sites comparison. Comparison of the active site residues of 4AG8 and 1URW.
Imaging with quantum states of light
Creators: name: Moreau, Paul-Antoine
name: Toninelli, Ermes
name: Gregory, Thomas
name: Padgett, Miles J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The production of pairs of entangled photons simply by focusing a laser beam onto a crystal with a non-linear optical response was used to test quantum mechanics and to open new approaches in imaging. The development of the latter was enabled by the emergence of single photon sensitive cameras able to characterize spatial correlations and high-dimensional entanglement. Thereby new techniques emerged such as the ghost imaging of objects - where the quantum correlations between photons reveal the image from photons that have never interacted with the object - or the imaging with undetected photons by using nonlinear interferometers. Additionally, quantum approaches in imaging can also lead to an improvement in the performance of conventional imaging systems. These improvements can be obtained by means of image contrast, resolution enhancement that exceed the classical limit and acquisition of sub-shot noise phase or amplitude images. In this review we discuss the application of quantum states of light for advanced imaging techniques.
LITERATURE INTERPRETATION ON THE EFFECT OF XENOBIOTICS ON CERTAIN PHYSIOLOGICAL INDICATORS OF FISH
Creators: name: Karimova, Irodaxon
name: Kuchkarova, Lyubov
name: Toxirova, Shaxnoza
Publisher: name: Zenodo
Year: 2025

description: As a result of the increased concentration of xenobiotics in water, it has a negative effect on the reproductive systems of fish. Since heavy metals accumulate in the body of fish, they can easily enter the human body and cause negative consequences. They cause disturbances in the endocrine system of adult female fish, and metal in the amount of 0.52 mg/l inhibits the growth of fish. In general, it has a negative effect on blood circulation, immune, respiratory and hematological systems. Excess copper accumulates mainly in the liver of fish. When examining the morphological and histological parameters of the fish liver (Cyprinus carpio), we can see that it caused liver discoloration and necrosis. High levels of copper block catalase enzymes in the liver, muscles, and wounds within 24 hours. Lead blocks the conduction of impulses in fish by reducing the activity of monoamine oxidase and acetylcholine esterase. Lead weakens the immune system and increases susceptibility to infections.
Investigation of Growth-Induced Strain in Monolayer MoS2 Grown by Chemical Vapor Deposition
Creators: name: Luo, Siwei
name: Cullen, Conor P.
name: Guo, Gencai
name: Zhong, Jianxin
name: Duesberg, Georg S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applied Physics (physics.app-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Two-dimensional materials such as transitional metal dichalcogenides exhibit unique optical and electrical properties. Here we report on the varying optical properties of CVD grown MoS2 monolayer flakes with different shapes. In particular, it is observed that the perimeter and the central region of the flakes have non-uniform photoluminescence (PL) energy and intensity. We quantified these effects systematically and propose that thermally induced strain during growth is the origin. The strain relaxation after transfer of the MoS2 flakes supports this explanation. Detailed investigations of the spatial distribution of the PL energy reveal that depending on the shape of the MoS2 flakes, the width of the strain field is different. Thus, our results help to elucidate the fundamental mechanisms responsible for the differences in PL and Raman signals between the perimeter region and the center region of monolayer MoS2 and suggest that the induced strain plays an important role in the growth of monolayer materials.
MOESM2 of Correction to: Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations
Creators: name: Shailima Rampogu
name: Ayoung Baek
name: Zeb, Amir
name: Lee, Keun
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Computational Biology

description: Additional file 7. 2D interaction representation of the reference compound and 1URW. Molecular interaction details of the reference compound.
Friction drilling
Creators: name: Bagheri-Bami, Alireza
Publisher: name: figshare
Year: 2021
Subjects: subject: Mechanical Engineering
subject: FOS: Mechanical engineering

description: Joining sheets and plates in the industry is of high importance. In the automotive and aerospace industry, using friction drilling technique is developing. In order to improve this method, different techniques have been used. In this research, applying ultrasonic vibration on the tool will be investigated. In this regard, a special tool was designed. Axial force and surface hardness were measured in friction drilling and ultrasonic assisted friction drilling. Higher rotational speed and lower feed rate induce lower axial force and higher surface hardness. In addition, ultrasonic vibration causes the surface to be harder with lower axial force. The results show that increasing the rotational speed and decreasing the feed rate in lathe machine causes axial force reduction and surface hardness increase in heat affect zone and thermomechanical region. Moreover, finite element method was carried out which indicated lower axial force occurs in ultrasonic assisted friction drilling comparing to conventional condition. Equivalent plastic strain was used to examine hardness value numerically. The obtained numerical and experiment results were in good agreement.
Noisy Toric code and random bond Ising model: The error threshold in a dual picture
Creators: name: Zarei, Mohammad Hossein
name: Ramezanpour, Abolfazl
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: It is known that noisy topological quantum codes are related to random bond Ising models where the order-disorder phase transition in the classical model is mapped to the error threshold of the corresponding topological code. On the other hand, there is a dual mapping between classical spin models and quantum Calderbank-Shor-Stean (CSS) states where the partition function of a classical model defined on a hypergraph $H$ is written as an inner product of a product state and a CSS state on dual hypergraph $\tilde{H}$. It is then interesting to see what is the interpretation of the classical phase transition in the random bond Ising model within the framework of the above duality and whether such an interpretation has any connection to the error threshold of the corresponding topological CSS code. In this paper, we consider the above duality relation specifically for a two-dimensional random bond Ising model. We show that the order parameter of this classical system is mapped to a coherence order parameter in a noisy Toric code model. In particular, a quantum phase transition from a coherent phase to a non-coherent phase occurs when the initial coherent state is affected by two sequences of bit-flip quantum channels where a quenched disorder is induced by measurement of the errors after the first channel. On the other hand, the above transition is directly related to error threshold of the Toric code model. Accordingly, and since the noisy process can be applied to other topological CSS states, we conclude that the dual correspondence can also provide a useful tool for the study of error thresholds in different topological CSS codes.
description: 11 pages, 8 figures, Accepted for publication in Physical Review A
Additional file 8 of Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex
Creators: name: Aydin, Dorothee
name: Filippov, Mikhail A
name: Jakob-Andreas Tschäpe
name: Gretz, Norbert
name: Prinz, Marco
name: Eils, Roland
name: Brors, Benedikt
name: Müller, Ulrike C
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Authors’ original file for figure 1
Geometric modular action and spontaneous symmetry breaking
Creators: name: Buchholz, Detlev
name: Summers, Stephen J.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study spontaneous symmetry breaking for field algebras on Minkowski space in the presence of a condition of geometric modular action (CGMA) proposed earlier as a selection criterion for vacuum states on general space-times. We show that any internal symmetry group must commute with the representation of the Poincare group (whose existence is assured by the CGMA) and each translation-invariant vector is also Poincare invariant. The subspace of these vectors can be centrally decomposed into pure invariant states and the CGMA holds in the resulting sectors. As positivity of the energy is not assumed, similar results may be expected to hold for other space--times.
description: Dedicated to the memory of Siegfried Schlieder. 17 pages, no figures. Revised version: simplified arguments and improved results; as to appear in Annales H. Poincare
title: Lomandra :
title: Richtlinien für die Durchführung der Prüfung auf Unterscheidbarkeit, Homogenität und Beständigkeit.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Plants
New Varieties of Plants
Lomandra

description: Zweck dieser Richtlinien („Prüfungsrichtlinien“) ist es, die in der Allgemeinen Einführung (Dokument TG/1/3) und deren verbundenen TGP-Dokumenten enthaltenen Grundsätze in detaillierte praktische Anleitung für die harmonisierte Prüfung der Unterscheidbarkeit, der Homogenität und der Beständigkeit (DUS) umzusetzen und insbesondere geeignete Merkmale für die DUS-Prüfung und die Erstellung harmonisierter Sortenbeschreibungen auszuweisen.
A Metamodel of the Telemac Errors
Creators: name: Zaoui, Fabrice
name: Goeury, Cédric
name: Audouin, Yoann
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Computer and information sciences

description: A Telemac study is a computationally intensive application for the real cases and in the context of quantifying or optimizing uncertainties, the running times can be too long. This paper is an example of an approximation of the Telemac results by a more abstract but significantly faster model. It shows how a metamodel can be easily built with low computational costs, and how it can help to understand and improve some global results of Telemac. I. INTRODUCTION Many sources of uncertainty lie in the real-world problems. Telemac as any model (i.e. approximation of reality) is error prone since uncertainties appear in the initial or boundary conditions, the system parameters, the modelling simplification or the numerical calculations themselves. Therefore, it is difficult to say with confidence if the design of a Telemac model has met all the requirements to be optimal. Calibration consists of tuning the model parameters so that the results are in better agreement with a set of observations. This phase is crucial before any further study can be conducted by avoiding a meaningless analysis or prediction based on false or too inaccurate results. This paper presents a statistical calibration of a Telemac 2D model (Gironde Estuary in France) with the learning of Telemac errors by a metamodel (i.e. a model of the simulation errors) to make the best use of limited observations data over a short time period. The metamodel here is a simplified version of Telemac behaving the same for all the locations where observation points are available. If the metamodel is correct, it will be able to compute as Telemac would do but with a highly reduced computational cost.
Distributional Soft Actor-Critic: Off-Policy Reinforcement Learning for Addressing Value Estimation Errors
Creators: name: Duan, Jingliang
name: Guan, Yang
name: Li, Shengbo Eben
name: Ren, Yangang
name: Cheng, Bo
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In reinforcement learning (RL), function approximation errors are known to easily lead to the Q-value overestimations, thus greatly reducing policy performance. This paper presents a distributional soft actor-critic (DSAC) algorithm, which is an off-policy RL method for continuous control setting, to improve the policy performance by mitigating Q-value overestimations. We first discover in theory that learning a distribution function of state-action returns can effectively mitigate Q-value overestimations because it is capable of adaptively adjusting the update stepsize of the Q-value function. Then, a distributional soft policy iteration (DSPI) framework is developed by embedding the return distribution function into maximum entropy RL. Finally, we present a deep off-policy actor-critic variant of DSPI, called DSAC, which directly learns a continuous return distribution by keeping the variance of the state-action returns within a reasonable range to address exploding and vanishing gradient problems. We evaluate DSAC on the suite of MuJoCo continuous control tasks, achieving the state-of-the-art performance.
Finite-Volume Partially-Quenched Two-Pion Amplitudes in the I=0 Channel
Creators: name: Lin, C. -J. D.
name: Martinelli, G.
name: Pallante, E.
name: Sachrajda, C. T.
name: Villadoro, G.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a study of the finite-volume two-pion matrix elements and correlation functions of the I=0 scalar operator, in full and partially quenched QCD, at one-loop order in chiral perturbation theory. In partially quenched QCD, when the sea and valence light quark masses are not equal, the lack of unitarity leads to the same inconsistencies as in quenched QCD and the matrix elements cannot be determined. It is possible, however, to overcome this problem by requiring the masses of the valence and sea quarks to be equal for the u and d quarks while keeping the strange quark (s) quenched (or partially quenched), but only in the kinematic region where the two-pion energy is below the two-kaon threshold. Although our results are obtained at NLO in chiral perturbation theory, they are more general and are also valid for non-leptonic kaon decays (we also study the matrix elements of (8,1) operators, such as the QCD penguin operator Q6). We point out that even in full QCD, where any problems caused by the lack of unitarity are clearly absent, there are practical difficulties in general, caused by the fact that finite-volume energy eigenstates are linear combination of two-pion, two-kaon and two-eta states. Our work implies that extracting Delta I=1/2, K-->pipi decay amplitudes from simulations with m_s=m_{d,u} is not possible in partially quenched QCD (and is very difficult in full QCD).
description: 10 pages
Rapid Rural Appraisal (RRA), Participatory Rural•Appraisal (PRA) and Their Application in the Global Environmental Facility (GEF- B) Program in China
Creators: name: Xiang, Zhu
name: Xiang, Zhu
Publisher: name: Unknown
Year: 1995
Subjects: subject: Community/Rural/Urban Development
subject: Environmental Economics and Policy
subject: Rapid Rural Appraisal
subject: Participatory Rural Appraisal
subject: Global Environmental FAcility
subject: (GEF-B)

description: This article, after introducing the concepts, principles and methodology involved, describes the applicability and efficiency of RRA (Rapid Rural Appraisal) and PRA (Participatory Rural Appraisal) in planning, community development as well as community joint-management within protected areas. Steps for the application of PRA and RRA are discussed, the framework and criteria for their application and evaluation are also presented.
Design and Experiment of 1LFQ-325 Pneumatic Reversible Plough
Creators: name: Zheng, Xuan
name: Chen, Xuefeng
name: Qin, Chaomin
name: Jia, Libo
name: Zheng, Xuan
name: Chen, Xuefeng
name: Qin, Chaomin
name: Jia, Libo
Publisher: name: Unknown
Year: 2013
Subjects: subject: Agribusiness
subject: Pneumatic
subject: Reversible plough
subject: Design
subject: Experiment

description: A pneumatic reversible plough is developed, which complements to the tractor of 25.7-36.8 kW. The plough adopts the cylinder as reversing mechanism between the right and left plough bodies, and the cylinder can substitute the mechanical reversing mechanism. The pneumatic turnover allows the plough to be operated easily and turned over flexibly. Field experiment results show that indicators of plough performance meet the requirements of the relevant national standards.
Molecular Gas Chemistry in AGN I. The IRAM Survey of NGC1068
Creators: name: Usero, A.
name: Garcia-Burillo, S.
name: Fuente, A.
name: Martin-Pintado, J.
name: Rodriguez-Fernandez, N. J.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: There is observational evidence that nuclear winds and X-rays can heavily influence the physical conditions and chemical abundances of molecular gas in the circumnuclear disks (CND) of Active Galactic Nuclei (AGN). In this paper we probe the chemical status of molecular gas in the CND of NGC1068, a prototypical Seyfert 2 galaxy. Precedent claims that the chemistry of molecular gas in the nucleus of NGC1068 is abnormal by galactic standards were based on the high HCN/CO luminosity ratio measured in the CND. Results from new observations obtained in this survey have served to derive abundances of molecular species such as SiO, CN, HCO+, HOC+, H13CO+ and HCO. These estimates are complemented by a re-evaluation of molecular abundances for HCN, CS and CO, based on previously published single-dish and interferometer observations of NGC1068. We report on the first detection of SiO emission in the CND of NGC1068. The estimated large abundance of SiO in the CND, X(SiO)~5-10x10^{-9}, cannot be attributed to shocks related to star formation, as there is little evidence of a recent starburst in the nucleus of NGC1068. Alternatively, we propose that silicon chemistry is driven by intense X-ray processing of molecular gas. We also report on the first extragalactic detection of the reactive ion HOC+. Most remarkably, the estimated HCO+/HOC+ abundance ratio in the nucleus of NGC1068, ~30-80, is the smallest ever measured in molecular gas. The abundances derived for all molecules that have been the subject of this survey are compared with the predictions of models invoking either oxygen-depletion or X-ray chemistry in molecular gas. Our conclusions favour an overall scenario where the CND of NGC1068 has become a giant X-ray Dominated Region (XDR).
description: 16 pages (including 9 figures and 6 tables); accepted by A&A
Are Massive Elementary Particles Black Holes?
Creators: name: Ward, B. F. L.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We use exact results in a new approach to quantum gravity to study the effect of quantum loop corrections on the behavior of the metric of space-time near the Schwarzschild radius of a massive point particle in the Standard Model. We show that the classical conclusion that such a system is a black hole is obviated. Phenomenological implications are discussed.
description: 9 pages, 1 figure; improved text
Discussion on Registration Validity Doctrine of Housing Land Use Right
Creators: name: Yu, Wenli
name: Yu, Wenli
Publisher: name: Unknown
Year: 2013
Subjects: subject: Agribusiness
subject: Real estate registration
subject: Housing land use right
subject: Registration validity
subject: Registration confrontation

description: Relationship between the registration and right change of housing land use right is not clearly stipulated in the Property Law. Land registration involves functions of private law and public law. It is partial to only considering private rights dimension when deciding whether registration validity doctrine or registration confrontation doctrine should be implemented in housing land use right. Compilation of land use planning, implementation of land use control and promotion of arrangement project in rural residential area all rely on sound and complete housing land registration data. To clarify housing land right adscription, eliminate hidden troubles causing housing land dispute and promote the establishment of harmonious countryside can never be achieved without housing land registration data. To carry out registration validity doctrine of housing land use right can effectively guide farmers’ registration behavior and thus build a perfect registration information system of housing land use right. After the cross-village and even cross-town arrangement in rural residential areas, rural acquaintance society has transformed into semi-acquaintance society and even stranger society. Therefore, housing land use right commending its existence with registration in public form has been a necessary choice in legislation.
MOESM1 of Correction to: Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations
Creators: name: Shailima Rampogu
name: Ayoung Baek
name: Zeb, Amir
name: Lee, Keun
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Computational Biology

description: Additional file 3. 2D interaction representation of the reference compound and 4AG8. Detailed molecular interactions of the reference compound.
A System of Local/Nonlocal $p$-Laplacians: The Eigenvalue Problem and Its Asymptotic Limit as $p\to\infty$
Creators: name: Buccheri, S.
name: da Silva, J. V.
name: de Miranda, L. H.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this work, given $p\in (1,\infty)$, we prove the existence and simplicity of the first eigenvalue $λ_p$ and its corresponding eigenvector $(u_p,v_p)$, for the following local/nonlocal PDE system \begin{equation}\label{Eq0} \left\{ \begin{array}{rclcl} -Δ_p u + (-Δ)^r_p u & = & \frac{2α}{α+β}λ|u|^{α-2}|v|^βu & \mbox{in} & Ω\\ -Δ_p v + (-Δ)^s_p v& = & \frac{2β}{α+β}λ|u|^α|v|^{β-2}v & \mbox{in} & Ω u& =& 0&\text{ on } & \mathbb{R}^N \setminus Ω v& =& 0&\text{ on } & \mathbb{R}^N \setminus Ω, \end{array} \right. \end{equation} where $Ω$$\subset$ $\mathbb{R}^N$ is a bounded open domain, $0
Analysis on Profit Quality of Small and Medium-sized Agricultural Enterprises: A Case Study of YM Industrial Co., Ltd in Guang’an City of Sichuan Province
Creators: name: Jiang, Ling
name: Luo, Huawei
name: Jiang, Ling
name: Luo, Huawei
Publisher: name: Unknown
Year: 2013
Subjects: subject: Agribusiness
subject: Small and medium-sized agricultural enterprises
subject: Analysis of financial statement
subject: Profit quality

description: For a long time, under the influence of system and environment and other factors, some small and medium-sized agricultural enterprises in China only seek growth of profit in quantity, but neglect the growth of profit in quality, leading to low profit quality. This study reasonably defines the concept of profit quality of small and medium-sized agricultural enterprises, and expounds general characteristics of high quality profit. On the basis of general factors influencing profit quality of enterprises, it builds indicator system for evaluating the profit quality of small and medium-sized agricultural enterprises. Also, it conducts an empirical analysis on profit quality of Chinese small and medium-sized enterprises with YM Industrial Co., Ltd in Guang’an City of Sichuan Province as an example.
MOESM2 of Cognitively normal women with Alzheimerâ€™s disease proteinopathy show relative preservation of memory but not of hippocampal volume
Creators: name: Caldwell, Jessica
name: Cummings, Jeffrey
name: Banks, Sarah
name: Palmqvist, Sebastian
name: Hansson, Oskar
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2: Regression Predicting Hippocampal Volumes with Cognitively Normal, Subjective Cognitive Decline, and Mild Cognitive Impairment Groups. This additional file contains a table summarizing the results of a regression predicting hippocampal volumes separated by diagnostic group.
The standard twist of L-functions revisited
Creators: name: Kaczorowski, J.
name: Perelli, A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11M41

description: The analytic properties of the standard twist $F(s,α)$, where $F(s)$ belongs to a wide class of $L$-functions, are of prime importance in describing the structure of the Selberg class. In this paper we present a deeper study of such properties. In particular, we show that $F(s,α)$ satisfies a functional equation of a new type, somewhat resembling that of the Hurwitz-Lerch zeta function. Moreover, we detect the finer polar structure of $F(s,α)$, characterizing in two different ways the occurrence of finitely or infinitely many poles as well as giving a formula for their residues.
description: 36 pages
Additional file of Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice
Creators: name: Burga, Laura N
name: Hu, Hai
name: Juvekar, Ashish
name: Tung, Nadine M
name: Troyan, Susan L
name: Hofstatter, Erin W
name: Wulf, Gerburg M
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file of Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice
Nuclear spin relaxation probed by a single quantum dot
Creators: name: Huettel, A. K.
name: Weber, J.
name: Holleitner, A. W.
name: Weinmann, D.
name: Eberl, K.
name: Blick, R. H.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present measurements on nuclear spin relaxation probed by a single quantum dot in a high-mobility electron gas. Current passing through the dot leads to a spin transfer from the electronic to the nuclear spin system. Applying electron spin resonance the transfer mechanism can directly be tuned. Additionally, the dependence of nuclear spin relaxation on the dot gate voltage is observed. We find electron-nuclear relaxation times of the order of 10 minutes.
Additional file of Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice
Creators: name: Burga, Laura N
name: Hu, Hai
name: Juvekar, Ashish
name: Tung, Nadine M
name: Troyan, Susan L
name: Hofstatter, Erin W
name: Wulf, Gerburg M
Publisher: name: figshare
Year: 2021
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file of Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice