cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Harm reduction workforce, behavioral health, and service delivery in the USA: a cross-sectional study
Creators: name: Ware, Orrin D.
name: Lombardi, Brooke N.
name: Lombardi, Brianna M.
name: de Saxe Zerden, Lisa
Publisher: name: Springer Nature
Year: 2024

description: Background Despite recent financial and policy support for harm reduction in the USA, information on the types of workers within organizations who design, implement, and actualize harm reduction services remains nascent. Little is known about how variability in the harm reduction workforce impacts referrals and linkages to other community supports. This exploratory mixed-methods study asked: (1) Who constitutes the harm reduction workforce? (2) Who provides behavioral health services within harm reduction organizations? (3) Are referral services offered and by whom? (4) Do referrals differ by type of harm reduction worker? Methods Purposive sampling techniques were used to distribute an electronic survey to U.S.-based harm reduction organizations. Descriptive statistics were conducted. Multivariate binary logistic regression models examined the associations (a) between the odds of the referral processes at harm reduction organizations and (b) between the provision of behavioral health services and distinct types of organizational staff. Qualitative data were analyzed using a hybrid approach of inductive and thematic analysis. Results Data from 41 states and Washington, D.C. were collected (N = 168; 48% response rate). Four primary types of workers were identified: community health/peer specialists (87%); medical/nursing staff (55%); behavioral health (49%); and others (34%). About 43% of organizations had a formal referral process; among these, only 32% had follow-up protocols. Qualitative findings highlighted the broad spectrum of behavioral health services offered and a broad behavioral health workforce heavily reliant on peers. Unadjusted results from multivariate models found that harm reduction organizations were more than 5 times more likely (95% CI [1.91, 13.38]) to have a formal referral process and 6 times more likely (95% CI [1.74, 21.52]) to have follow-up processes when behavioral health services were offered. Organizations were more than two times more likely (95% CI [1.09, 4.46]) to have a formal referral process and 2.36 (95% CI [1.11, 5.0]) times more likely to have follow-up processes for referrals when behavioral health providers were included. Conclusions The composition of the harm reduction workforce is occupationally diverse. Understanding the types of services offered, as well as the workforce who provides those services, offers valuable insights into staffing and service delivery needs of frontline organizations working to reduce morbidity and mortality among those who use substances. Workforce considerations within U.S.-based harm reduction organizations are increasingly important as harm reduction services continue to expand.
Einige Bemerkungen zu Animationsfilm und Performance in Österreich
Creators: name: Zakravsky, Katherina T.
Publisher: name: figshare
Year: 2019
Subjects: subject: 190204 Film and Television
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 190404 Drama, Theatre and Performance Studies
subject: 200204 Cultural Theory
subject: FOS: Other humanities

description: „Einige Bemerkungen zu Animationsfilm und Performance in Österreich“ in Christian Dewald / Sabine Groschup / Mara Mattuschka / Thomas Renoldner (Hg.): Die Kunst des Einzelbilds. Animation in Österreich – 1832 bis heute, Wien: Verlag Filmarchiv Austria, 2010, 281-299.
A (German) in-depth analysis of several works from the 1970ties to the Zero-Years on the various translations and synergies of the composed/moving still image ("animation"), extended cinema and performance in Austria. Focus on works by Export, Mattuschka, Scheirl, Arnold, Aschwanden, some of which the author is personally familiar with and has cooperated with for a long time.
title: A Deterministic Filter for Non-Gaussian Bayesian Estimation
Creators: name: Pajonk, Oliver
name: Rosic, Bojana
name: Litvinenko, Alexander
name: Matthies, Hermann
Publisher: name: Institut für Wissenschaftliches Rechnen
Year: 2011
Subjects: subject: Bayesian estimation
subject: polynomial chaos expansion
subject: Kalman filter
subject: inverse problem
subject: 004

description: We present a fully deterministic method to compute sequential updates for stochastic state estimates of dynamic models from noisy measurements. It does not need any assumptions about the type of distribution for either data or measurement — in particular it does not have to assume any of them as Gaussian. It is based on a polynomial chaos expansion (PCE) of the stochastic variables of the model. We use a minimum variance estimator that combines an a priori state estimate and noisy measurements in a Bayesian way. For computational purposes, the update equation is projected onto a finite-dimensional PCE-subspace. The resulting Kalman-type update formula for the PCE coefficients can be efficiently computed solely within the PCE. As it does not rely on sampling, the method is deterministic, robust, and fast. In this paper we discuss the theory and practical implementation of the method. The original Kalman filter is shown to be a low-order special case. In a first experiment, we perform a bi-modal identification using noisy measurements. Additionally, we provide numerical experiments by applying it to the well known Lorenz-84 model and compare it to a related method, the ensemble Kalman filter.
description: Informatik-Berichte der Technischen Universität Braunschweig, vol. 2011-04
Modelling Conditional Dependence Between Response Time and Accuracy in Cognitive Diagnostic Models
Creators: Bezirhan, Ummugul
Publisher: name: Columbia University
Year: 2021
Subjects: subject: Educational tests and measurements
subject: Statistics
subject: FOS: Mathematics
subject: Education
subject: Cognitive Diagnostic Battery
subject: Item response theory--Mathematical models

description: With the novel data collection tools and diverse item types, computer-based assessments allow to easily obtain more information about an examinee’s response process such as response time (RT) data. This information has been utilized to increase the measurement precision about the latent ability in the response accuracy models. Van der Linden’s (2007) hierarchical speed-accuracy model has been widely used as a joint modelling framework to harness the information from RT and the response accuracy, simultaneously. The strict assumption of conditional independence between response and RT given latent ability and speed is commonly imposed in the joint modelling framework. Recently multiple studies (e.g., Bolsinova & Maris, 2016; Bolsinova, De Boeck, & Tijmstra, 2017a; Meng, Tao, & Chang, 2015) have found violations of the conditional independence assumption and proposed models to accommodate this violation by modelling conditional dependence of responses and RTs within a framework of Item Response Theory (IRT). Despite the widespread usage of Cognitive Diagnostic Models as formative assessment tools, the conditional joint modelling of responses and RTs has not yet been explored in this framework. Therefore, this research proposes a conditional joint response and RT model in CDM with an extended reparametrized higher-order deterministic input, noisy ‘and’ gate (DINA) model for the response accuracy. The conditional dependence is modelled by incorporating item-specific effects of residual RT (Bolsinova et al., 2017a) on the slope and intercept of the accuracy model. The effects of ignoring the conditional dependence on parameter recovery is explored with a simulation study, and empirical data analysis is conducted to demonstrate the application of the proposed model. Overall, modelling the conditional dependence, when applicable, has increased the correct attribute classification rates and resulted in more accurate item response parameter estimates.
Clusia tigrina
Creators: name: Kazerani, F.
name: Beuk, P.
name: Farashiani, M. E.
name: Kiasari, Sh. Mohammadnezhad
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Clusiaceae
Clusia
Clusia tigrina

description: Clusia tigrina (Fallén, 1820) (figs 2–3)
M a t e r i a l e x a m i n e d: Iran: Golestan province, Shast-Kola forests [36°43'00.7" N 54°23'13.7" E], 1271 m, pan traps, 12.07.2017, 1 ♀; Mazandaran province, Neka [36° 22'42.03" N 53° 33.05'52.7" E], 1210 m, sweeping net, 2 ♀, 1 Ơ (Kazerani & Mohammadnezhad Kiasari).
 D i a g n o s t i c c h a r a c t e r s: Palpi white; antenna scape and pedicel light yellow, postpedicel yellow, black at apex; thorax yellow with 2 brown on dorsocenteral part from transverse suture to near the scutellum; scutellum totally yellow; scutum laterally with a brown band from humeral to base of wing; Wings with a dark cloud around R 1 and base of R 2+3, R 4+5, also with a dark cloud around the R 2+3, R 4+5 and M 1+2 at apex, M 1+2 with a black cloud at middle around dm-cu, legs totally yellow, coxa white; Abdomen tergites yellow, 2nd tergite with 2 brown spots, 3rd–4th tergites with brown band.
D i s t r i b u t i o n: Palearctic: Europe, Russia.
description: Published as part of Kazerani, F., Beuk, P., Farashiani, M. E. & Kiasari, Sh. Mohammadnezhad, 2020, First Records Of The Rare Family Clusiidae (Diptera, Opomyzoidea) From Iran, pp. 31-34 in Zoodiversity 54 (1) on page 32, DOI: 10.15407/zoo2020.01.031, http://zenodo.org/record/6455412
Modification of the X-ray diffraction signal intensity at long-time exposure from Hierarchical architecture of spider attachment setae reconstructed from scanning nanofocus X-ray diffraction data
Creators: name: Schaber, Clemens F.
name: Flenner, Silja
name: Glisovic, Anja
name: Krasnov, Igor
name: Rosenthal, Martin
name: Stieglitz, Hergen
name: Krywka, Christina
name: Burghammer, Manfred
name: Müller, Martin
name: Gorb, Stanislav N.
Publisher: name: The Royal Society
Year: 2019

description: Figure S1. Modification of the X-ray diffraction signal intensity at 400-fold successive exposure by 0.1 s of an attachment hair to the focused X-ray beam at the ESRF. (a) Decrease of the equatorial 110 chitin wide-angle diffraction reflection. The exponential fit yields a half-life of signal intensity of 6.9 s exposure as indicated by the dashed line. The data points are shifted to the zero line of the asymptotic line fit. Negative intensity values are caused by subtraction of the background signal. (b) Increase of the SAXS signal intensity.
Scham. Der Menschheit bestes Teil
Creators: name: Zakravsky, Katherina T.
Publisher: name: figshare
Year: 2019
Subjects: subject: 220318 Psychoanalytic Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Archaeology
subject: 130308 Gender, Sexuality and Education
subject: FOS: Educational sciences

description: German text on the overcoming of Jacques Lacan's binary symbolism of female and male genitalia with reference to the fresco of Roman initiation in the "villa de misteri" in Pompeji.Also an essay on the double meaning of shame and the German word for the female genital, "Scham" and its psycho-cultural implications.
Alley cropping diversifies your farm and improves the environment - Sistemas 'Alley cropping' diversificam a sua exploração e melhoram o ambiente
Creators: name: Rois, Mercedes
name: Herder, Michael Den
name: Mattila, Iiris
Publisher: name: Zenodo
Year: 2018
Subjects: productivity; combinations; diversification; tree rows; crops
produtividade; combinações de espécies; diversificação; filas de árvores; culturas; silvoarável

description: Factsheet número 11 do projeto AFINET
Denser Egyptian Fractions
Creators: name: Martin, Greg
Publisher: name: arXiv
Year: 1998
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11D68

description: An Egyptian fraction is a sum of distinct unit fractions (reciprocals of positive integers). We show that every rational number has Egyptian fraction representations where the number of terms is of the same order of magnitude as the largest denominator, improving a result from an earlier paper to best-possible form. We also settle, in best-possible form, the related problem of how small M_t(r) can be such that there is an Egyptian fraction representation of r with exactly t terms, the denominators of which are all at most M_t(r). We also consider the following problems posed by Erdos and Graham: the set of integers that cannot be the largest denominator of an Egyptian fraction representation of 1 is infinite - what is its order of growth? How about those integers that cannot be the second-largest (third-largest, etc.) denominator of such a representation? In the latter case, we show that only finitely many integers cannot be the second-largest (third-largest, etc.) denominator of such a representation; while in the former case, we show that the set of integers that cannot be the largest denominator of such a representation has density zero, and establish its order of growth. Both results extend to representations of any positive rational number.
description: 26 pages; sequel to "Dense Egyptian Fractions" (math.NT/9804045)
Adding Value by Combining Business and Sensor Data: An Industry 4.0 Use Case
Creators: name: Hesse, Guenter
name: Matthies, Christoph
name: Sinzig, Werner
name: Uflacker, Matthias
Publisher: name: arXiv
Year: 2019
Subjects: subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: Industry 4.0 and the Internet of Things are recent developments that have lead to the creation of new kinds of manufacturing data. Linking this new kind of sensor data to traditional business information is crucial for enterprises to take advantage of the data's full potential. In this paper, we present a demo which allows experiencing this data integration, both vertically between technical and business contexts and horizontally along the value chain. The tool simulates a manufacturing company, continuously producing both business and sensor data, and supports issuing ad-hoc queries that answer specific questions related to the business. In order to adapt to different environments, users can configure sensor characteristics to their needs.
description: Accepted at International Conference on Database Systems for Advanced Applications (DASFAA 2019)
Additional file 4 of Integrated small RNA and mRNA expression profiles reveal miRNAs and their target genes in response to Aspergillus flavus growth in peanut seeds
Creators: name: Zhao, Chuanzhi
name: Li, Tingting
name: Zhao, Yuhan
name: Zhang, Baohong
name: Li, Aiqin
name: Zhao, Shuzhen
name: Hou, Lei
name: Xia, Han
name: Fan, Shoujin
name: Qiu, Jingjing
name: Li, Pengcheng
name: Zhang, Ye
name: Guo, Baozhu
name: Wang, Xingjun
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 4: Table S1. Summary of small RNA reads from the individual libraries.
title: 01_1245
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Killing Initial Data
Creators: name: Beig, R.
name: Chrusciel, Piotr T.
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study space-time Killing vectors in terms of their "lapse and shift" relative to some spacelike slice. We give a necessary and sufficient condition in order for these lapse-shift pairs, which we call Killing initial data (KID'S), to form a Lie algebra under the bracket operation induced by the Lie commutator of vector fields on space-time. This result is applied to obtain a theorem on the periodicity of orbits for a class of Killing vector fields in asymptotically flat space-times.
description: 17 pages
The polymer phase of the TDAE-C$_{60}$ organic ferromagnet
Creators: name: Garaj, Slaven
name: Kambe, Takashi
name: Forró, László
name: Sienkiewicz, Andrzej
name: Fujiwara, Motoyasu
name: Oshima, Kokichi
Publisher: name: arXiv
Year: 2002
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The high-pressure Electron Spin Resonance (ESR) measurements were preformed on TDAE-C$_{60}$ single crystals and stability of the polymeric phase was established in the $P - T$ parameter space. At 7 kbar the system undergoes a ferromagnetic to paramagnetic phase transition due to the pressure-induced polymerization. The polymeric phase remains stable after the pressure release. The depolymerization of the pressure-induced phase was observed at the temperature of 520 K. Below room temperature, the polymeric phase behaves as a simple Curie-type insulator with one unpaired electron spin per chemical formula. The TDAE$^+$ donor-related unpaired electron spins, formerly ESR-silent, become active above the temperature of 320 K and the Curie-Weiss behavior is re-established.
description: Submitted to Phys. Rev. B
Confinement, solitons and the equivalence between the sine-Gordon and massive Thirring models
Creators: name: Blas, Harold
name: Ferreira, L. A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We consider a two-dimensional integrable and conformally invariant field theory possessing two Dirac spinors and three scalar fields. The interaction couples bilinear terms in the spinors to exponentials of the scalars. Its integrability properties are based on the sl(2) affine Kac-Moody algebra, and it is a simple example of the so-called conformal affine Toda theories coupled to matter fields. We show, using bosonization techniques, that the classical equivalence between a U(1) Noether current and the topological current holds true at the quantum level, and then leads to a bag model like mechanism for the confinement of the spinor fields inside the solitons. By bosonizing the spinors we show that the theory decouples into a sine-Gordon model and free scalars. We construct the two-soliton solutions and show that their interactions lead to the same time delays as those for the sine-Gordon solitons. The model provides a good laboratory to test duality ideas in the context of the equivalence between the sine-Gordon and Thirring theories.
description: LaTeX, 26 pages
Modeling the impact of internal state on sensory processing
Creators: Lindsay, Grace Wilhelmina
Publisher: name: Columbia University
Year: 2018
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Biometry
subject: Neural circuitry
subject: Sensory stimulation
subject: Perception

description: Perception is the result of more than just the unbiased processing of sensory stimuli. At each moment in time, sensory inputs enter a circuit already impacted by signals of arousal, attention, and memory. This thesis aims to understand the impact of such internal states on the processing of sensory stimuli. To do so, computational models meant to replicate known biological circuitry and activity were built and analyzed. Part one aims to replicate the neural activity changes observed in auditory cortex when an animal is passively versus actively listening. In part two, the impact of selective visual attention on performance is probed in two models: a large-scale abstract model of the visual system and a smaller, more biologically-realistic one. Finally in part three, a simplified model of Hebbian learning is used to explore how task context comes to impact prefrontal cortical activity. While the models used in this thesis range in scale and represent diverse brain areas, they are all designed to capture the physical processes by which internal brain states come to impact sensory processing.
General-relativistic Model of Magnetically Driven Jet
Creators: name: Rogava, A. D.
name: Khujadze, G. R.
Publisher: name: arXiv
Year: 1996
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The general scheme for the construction of the general-relativistic model of the magnetically driven jet is suggested. The method is based on the usage of the 3+1 MHD formalism. It is shown that the critical points of the flow and the explicit radial behavior of the physical variables may be derived through the jet ``profile function."
description: 12 pages, LaTex, no figures
title: Direct Bayesian Update of Polynomial Chaos Representations
Creators: name: Rosic, Bojana
name: Litvinenko, Alexander
name: Pajonk, Oliver
name: Matthies, Hermann
Publisher: name: Institut für Wissenschaftliches Rechnen
Year: 2011
Subjects: subject: Minimum quadratischen und minimum-Varianz Fehler
subject: lineares Baye's aktualisieren
subject: Kalman-Filter
subject: minimum squared error estimate
subject: minimum variance estimate
subject: polynomial chaos expansion
subject: linear Bayesian update
subject: Kalman filter
subject: 004

description: We present a fully deterministic approach to a probabilistic interpretation of inverse problems in which unknown quantities are represented by random fields or processes, described by a non-Gaussian prior distribution. The description of the introduced random fields is given in a ``white noise'' framework, which enables us to solve the stochastic forward problem through Galerkin projection onto polynomial chaos. With the help of such representation, the probabilistic identification problem is cast in a polynomial chaos expansion setting and the linear Bayesian form of updating. This representation leads to a corresponding new formulation of the minimum squared error estimator, obtained by its additional projection onto the polynomial chaos basis. 
By introducing the Hermite algebra this becomes a direct, purely algebraic way of computing the posterior, which is inexpensive to evaluate. In addition, we show that the well-known Kalman filter method is the low order part of this update. The proposed method has been tested on a stationary diffusion equation with prescribed source terms, characterised by an uncertain conductivity parameter which is then identified from limited and noisy data obtained by a measurement of the diffusing quantity.
description: Informatik-Berichte der Technischen Universität Braunschweig, vol. 2011-02
Data-driven model of the solar corona above an active region
Creators: name: Warnecke, Jörn
name: Peter, Hardi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We aim to reproduce the structure of the corona above a solar active region as seen in the extreme ultraviolet (EUV) using a three-dimensional magnetohydrodynamic (3D MHD) model. The 3D MHD data-driven model solves the induction equation and the mass, momentum, and energy balance. To drive the system, we feed the observed evolution of the magnetic field in the photosphere of the active region AR 12139 into the bottom boundary. This creates a hot corona above the cool photosphere in a self-consistent way. We synthesize the coronal EUV emission from the densities and temperatures in the model and compare this to the actual coronal observations. We are able to reproduce the overall appearance and key features of the corona in this active region on a qualitative level. The model shows long loops, fan loops, compact loops, and diffuse emission forming at the same locations and at similar times as in the observation. Furthermore, the low-intensity contrast of the model loops in EUV matches the observations. In our model the energy input into the corona is similar as in the scenarios of fieldline-braiding or flux-tube tectonics, that is, energy is transported to the corona through the driving of the vertical magnetic field by horizontal photospheric motions. The success of our model shows the central role that this process plays for the structure, dynamics, and heating of the corona.
description: 5 pages, 3 Figures, published in A&A letters
Exploration of good and bad structural fingerprints for inhibition of indoleamine-2,3-dioxygenase enzyme in cancer immunotherapy using Monte Carlo optimization and Bayesian classification QSAR modeling
Creators: name: Sanskar Jain
name: Bhagwati Bhardwaj
name: Sk. Abdul Amin
name: Nilanjan Adhikari
name: Jha, Tarun
name: Shovanlal Gayen
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Indoleamine-2,3-dioxygenase 1 (IDO1) is an extrahepatic, heme-containing and tryptophan-catalyzing enzyme responsible for causing blockade of T-cell proliferation and differentiation by depleting tryptophan level in cancerous cells. Therefore, inhibition of IDO1 may be a useful strategy for immunotherapy against cancer. In this study, 448 structurally diverse IDO1 inhibitors with a wide range of activity has been taken into consideration for classification QSAR analysis through Monte Carlo Optimization by using different splits as well as different combinations of SMILES-based, graph-based and hybrid descriptors. The best model from Monte Carlo optimization was interpreted to find out the good and bad structural fingerprints for IDO1 and further justified by using Bayesian classification QSAR modeling. Among the three splits in Monte Carlo optimization, the statistics of the best model was obtained from Split 3: sensitivity = 0.87, specificity = 0.91, accuracy = 0.89 and MCC = 0.78. In Bayesian classification modeling, the ROC scores for training and test set were found to be 0.91 and 0.86, respectively. The combined modeling analysis revealed that the presence of aryl hydrazyl sulphonyl moiety, furazan ring, halogen substitution, nitro group and hetero atoms in aromatic system can be very useful in designing IDO1 inhibitors. All the good and bad structural fingerprints for IDO1 were identified and are justified by correlating these fragments to the inhibition of IDO1 enzyme. These structural fingerprints will guide the researchers in this field to design better inhibitors against IDO1 enzyme for cancer immunotherapy. Communicated by Ramaswamy H. Sarma
NOEMA maps the CO $J = 2-1$ environment of the red supergiant $μ$ Cep
Creators: name: Montargès, M.
name: Homan, W.
name: Keller, D.
name: Clementel, N.
name: Shetye, S.
name: Decin, L.
name: Harper, G. M.
name: Royer, P.
name: Winters, J. M.
name: Bertre, T. Le
name: Richards, A. M. S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Red supergiant stars are surrounded by a gaseous and dusty circumstellar environment created by their mass loss which spreads heavy elements into the interstellar medium. The structure and the dynamics of this envelope are crucial to understand the processes driving the red supergiant mass loss and the shaping of the pre-supernova ejecta. We have observed the emission from the CO $J = 2-1$ line from the red supergiant star $μ$~Cep with the NOEMA interferometer. In the line the synthesized beam was $0.92 \times 0.72$~arcsec ($590 \times 462$~au at 641~pc). The continuum map shows only the unresolved contribution of the free-free emission of the star chromosphere. The continuum-subtracted channel maps reveal a very inhomogeneous and clumpy circumstellar environment. In particular, we detected a bright CO clump, as bright as the central source in the line, at 1.80~arcsec south-west from the star, in the blue channel maps. After a deprojection of the radial velocity assuming two different constant wind velocities, the observations were modelled using the 3D radiative transfer code \textsc{lime} to derive the characteristics of the different structures. We determine that the gaseous clumps observed around $μ$~Cep are responsible for a mass loss rate of $(4.9 \pm 1.0) \times 10^{-7}~{\rm M}_\odot\,{\rm yr}^{-1}$, in addition to a spatially unresolved wind component with an estimated mass-loss rate of $2.0 \times 10^{-6}~{\rm M}_\odot\,{\rm yr}^{-1}$. Therefore, the clumps have a significant role in $μ$~Cep's mass loss ($\ge 25 \%$). We cannot exclude that the unresolved central outflow may be made of smaller unresolved clumps.
description: 15 pages, 4 tables, 9 figures. 2nd version : one co-author removed and acknowledgement updated (consistent with erratum https://doi.org/10.1093/mnras/stz1006)
Contrasting DNA methylation responses of inbred fish lines to different rearing environments
Creators: name: Waldir M. Berbel-Filho
name: Deiene Rodríguez-Barreto
name: Berry, Nikita
name: Leaniz, Carlos Garcia De
name: Consuegra, Sofia
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Developmental Biology
subject: Marine Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: Epigenetic mechanisms generate plastic phenotypes that can become locally adapted across environments. Disentangling genomic from epigenomic variation is challenging in sexual species due to genetic variation among individuals, but it is easier in self-fertilizing species. We analysed DNA methylation patterns of two highly inbred strains of a naturally self-fertilizing fish reared in two contrasting environments to investigate the obligatory (genotype-dependent), facilitated (partially depend on the genotype) or pure (genotype-independent) nature of the epigenetic variation. We found higher methylation differentiation between genotypes than between environments. Most methylation differences between environments common to both strains followed a pattern where the two genotypes (inbred lines) responded to the same environmental context with contrasting DNA methylation levels (facilitated epialleles). Our findings suggest that, at least in part, DNA methylation could depend on the dynamic interaction between the genotype and the environment, which could explain the plasticity of epigenetically mediated phenotypes.
Non-spherical equilibrium shapes in the liquid drop model
Creators: name: Frank, Rupert L.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We prove the existence of a family of volume-constrained critical points of the liquid drop functional, which are cylindrically but not spherically symmetric. This family bifurcates from the ball and exchanges stability with it.
description: 25 pages; contribution to the proceedings of the ICMP 2018; second version contains more precise energy asymptotics (new Theorem 6)
title: Zeitschrift des Allgemeinen Österreichischen Apothekervereines 23. Jahrgang 1885
title: Österreichische Zeitschrift für Pharmacie 39. Jahrgang
titleType: AlternativeTitle
Creators: name: :None
Publisher: name: Allgemeiner Österreichischer Apothekerverein
Year: 1885
Subjects: subject: 615

description: Zeitschrift des Allgemeinen Österreichischen Apothekervereines: 1. 1863 - 37. 1899, vol. 23. 1885
Equilibrium Chemical Engines
Creators: name: Shibata, Tatsuo
name: Sasa, Shin-ichi
Publisher: name: arXiv
Year: 1997
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Quantitative Biology (q-bio)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: An equilibrium reversible cycle with a certain engine to transduce the energy of any chemical reaction into mechanical energy is proposed. The efficiency for chemical energy transduction is also defined so as to be compared with Carnot efficiency. Relevance to the study of protein motors is discussed. KEYWORDS: Chemical thermodynamics, Engine, Efficiency, Molecular machine.
description: 5 pages, latex
The impact of non-ideal surfaces on the solid-water interaction: a time-resolved adsorption study
Creators: name: May, Matthias M.
name: Stange, Helena
name: Weinrich, Jonas
name: Hannappel, Thomas
name: Supplie, Oliver
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The initial interaction of water with semiconductors determines the electronic structure of the solid-liquid interface. The exact nature of this interaction is, however, often unknown. Here, we study gallium phosphide-based surfaces exposed to H2O by means of in situ reflection anisotropy spectroscopy. We show that the introduction of typical imperfections in the form of surface steps or trace contaminants not only changes the dynamics of the interaction, but also its qualitative nature. This emphasises the challenges for the comparability of experiments with (idealised) electronic structure models for electrochemistry.
description: 14 pages, 9 figures, submission to SciPost
Propagation of maximally localized Wannier functions in real-time TDDFT
Creators: name: Yost, Dillon C.
name: Yao, Yi
name: Kanai, Yosuke
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Real-time, time-dependent density functional theory (RT-TDDFT) has gained popularity as a first-principles approach to study a variety of excited-state phenomena such as optical excitations and electronic stopping. Within RT-TDDFT simulations, the gauge freedom of the time-dependent electronic orbitals can be exploited for numerical and scientific convenience while the unitary transformation does not alter physical properties calculated from the quantum dynamics of electrons. Exploiting this gauge freedom, we demonstrate propagation of maximally localized Wannier functions within RT-TDDFT. We illustrate its great utility through a number of examples including its application to optical excitation in extended systems using the so-called length gauge, interpreting electronic stopping excitation, and simulating electric field-driven quantized charge transport. We implemented the approach within our plane-wave pseudopotential RT-TDDFT module of the QB@LL code, and performance of the implementation is also discussed.
Seven years of research on reclamation using biosolids at Highland Valley Copper
Creators: name: Straker, Justin
name: Hamaguchi, Bob A.
name: Jones, Carol Elizabeth, 1953-
name: Freberg, Mark
Publisher: name: The University of British Columbia
Year: 2009

description: A research program was initiated at the Highland Valley Copper mine near Logan Lake, B.C. in 1996 to test application of de-watered sludge from municipal wastewater treatment plants (biosolids) as a potential reclamation treatment and to assess environmental effects. Control treatments were included in the study design to compare biosolids application with standard reclamation treatments using annual application of chemical fertilizers during the first four to five years of vegetation establishment. The biosolids research program has included monitoring to assess changes to soil, soil water and vegetation chemistry, and effects on vegetation cover and biomass production on the treated sites. This paper presents the results to date, including findings on element mobility following biosolids application, and effects on vegetation chemistry and soil nutrient capital. The potential benefits and limitations of biosolids application in Highland Valley Copper's reclamation programs are summarized.
Is there a "native" band gap in ion conducting glasses?
Creators: name: Dyre, Jeppe C.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: It is suggested that the spectrum of ion site energies in glasses exhibits a band gap, establishing an analogy between ion conducting glasses and intrinsic semiconductors. This implies that ion conduction in glasses takes place via vacancies and interstitial ions (as in crystals).
description: 3 pages
title: Zeitschrift des Allgemeinen Österreichischen Apothekervereines 24. Jahrgang 1886
title: Österreichische Zeitschrift für Pharmacie 40. Jahrgang
titleType: AlternativeTitle
Creators: name: :None
Publisher: name: Allgemeiner Österreichischer Apothekerverein
Year: 1886
Subjects: subject: 615

description: Zeitschrift des Allgemeinen Österreichischen Apothekervereines: 1. 1863 - 37. 1899, vol. 24. 1886
Citations and References for observations of infanticide by females from The evolution of infanticide by females in mammals
Creators: name: Lukas, Dieter
name: Huchard, Elise
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: Two tables with entries for each species included in the analyses and a bibliography
Models for managing surge capacity in the face of an influenza epidemic
Creators: Zenteno, Ana
Publisher: name: Columbia University
Year: 2013
Subjects: Operations research
Public health

description: Influenza pandemics pose an imminent risk to society. Yearly outbreaks already represent heavy social and economic burdens. A pandemic could severely affect infrastructure and commerce through high absenteeism, supply chain disruptions, and other effects over an extended and uncertain period of time. Governmental institutions such as the Center for Disease Prevention and Control (CDC) and the U.S. Department of Health and Human Services (HHS) have issued guidelines on how to prepare for a potential pandemic, however much work still needs to be done in order to meet them. From a planner's perspective, the complexity of outlining plans to manage future resources during an epidemic stems from the uncertainty of how severe the epidemic will be. Uncertainty in parameters such as the contagion rate (how fast the disease spreads) makes the course and severity of the epidemic unforeseeable, exposing any planning strategy to a potentially wasteful allocation of resources. Our approach involves the use of additional resources in response to a robust model of the evolution of the epidemic as to hedge against the uncertainty in its evolution and intensity. Under existing plans, large cities would make use of networks of volunteers, students, and recent retirees, or borrow staff from neighboring communities. Taking into account that such additional resources are likely to be significantly constrained (e.g. in quantity and duration), we seek to produce robust emergency staff commitment levels that work well under different trajectories and degrees of severity of the pandemic. Our methodology combines Robust Optimization techniques with Epidemiology (SEIR models) and system performance modeling. We describe cutting-plane algorithms analogous to generalized Benders' decomposition that prove fast and numerically accurate. Our results yield insights on the structure of optimal robust strategies and on practical rules-of-thumb that can be deployed during the epidemic. To assess the efficacy of our solutions, we study their performance under different scenarios and compare them against other seemingly good strategies through numerical experiments. This work would be particularly valuable for institutions that provide public services, whose operations continuity is critical for a community, especially in view of an event of this caliber. As far as we know, this is the first time this problem is addressed in a rigorous way; particularly we are not aware of any other robust optimization applications in epidemiology.
The Making of Francis Grose's Antiquities: Evidence from Sussex
Creators: name: Farrant, John H
Publisher: name: Archaeology Data Service
Year: 2021

description: Sussex Archaeological Collections, 131, 152-158
description: Francis Grose ( 1731-91) drew numerous ancient monuments throughout Great Britain and Ireland over 40 years. From these and other artists' pictures about 1,000 engravings were published, accompanied by carefully prepared explanatory text. Using material relating to the Sussex sections, this article provides insight into Grose's working methods, and publishesfor the first time a plan of Brighton in 1761 probably intended for inclusion. The plan purports to show the layout of the old town beneath the cliff before it was inundated by the sea, but it cannot be relied upon.
Contrasting DNA methylation responses of inbred fish lines to different rearing environments
Creators: name: Waldir M. Berbel-Filho
name: Deiene Rodríguez-Barreto
name: Berry, Nikita
name: Leaniz, Carlos Garcia De
name: Consuegra, Sofia
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Developmental Biology
subject: Marine Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: Epigenetic mechanisms can generate plastic phenotypes that can become locally adapted across environments. Disentangling genomic from epigenomic variation is challenging in sexual species due to genetic variation among individuals, but it is easier in self-fertilising species. We analysed DNA methylation patterns of two highly inbred strains of a naturally self-fertilising fish reared in two contrasting environments to analyse the obligatory (genotype-dependent), facilitated (partially depend on the genotype) or pure (genotype-independent) nature of the epigenetic variation. We found higher methylation differentiation between genotypes than between environments. Most methylation differences between environments common to both strains followed a pattern where the two genotypes (inbred lines) responded to the same environmental context with contrasting DNA methylation levels (facilitated epialleles). Our findings suggest that, at least in part, DNA methylation could depend on the dynamic interaction between the genotype and the environment, which could explain the plasticity of epigenetically-mediated phenotypes.
Diffusion dynamics of supercooled water modeled with the cage-jump motion and hydrogen-bond rearrangement
Creators: name: Kikutsuji, Takuma
name: Kim, Kang
name: Matubayasi, Nobuyuki
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The slow dynamics of glass-forming liquids is generally ascribed to the cage-jump motion. In the cage-jump picture, a molecule remains in a cage formed by neighboring molecules, and after a sufficiently long time, it jumps to escape from the original position by cage-breaking. The clarification of the cage-jump motion is therefore linked to unraveling the fundamental element of the slow dynamics. Here, we develop a cage-jump model for the dynamics of supercooled water. The caged and jumping states of a water molecule are introduced with respect to the hydrogen-bond (H-bond) rearrangement process, and describe the motion in supercooled states. It is then demonstrated from the molecular dynamics simulation of the TIP4P/2005 model that the characteristic length and time scales of cage-jump motions provide a good description of the self-diffusion constant that is determined in turn from the long-time behavior of the mean square displacement. Our cage-jump model thus enables to connect between H-bond dynamics and molecular diffusivity.
description: 7 pages, 5 figures, J. Chem. Phys. for "Special Topic on Chemical Physics of Supercooled Water"
Perturbation of a lattice spectral band by a nearby resonance
Creators: name: Motovilov, A. K.
name: Sandhas, W.
name: Belyaev, V. B.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mathematical Physics (math-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A soluble model of weakly coupled "molecular" and "nuclear" Hamiltonians is studied in order to exhibit explicitly the mechanism leading to the enhancement of fusion probability in case of a narrow near-threshold nuclear resonance. We, further, consider molecular cells of this type being arranged in lattice structures. It is shown that if the real part of the narrow nuclear resonance lies within the molecular band generated by the intercellular interaction, an enhancement, proportional to the inverse width of the nuclear resonance, is to be expected.
description: RevTeX, 2 figures within the file. In May 2000 the title changed and some minor corrections have been done
Credits for drawings included in Figure 1 from The evolution of infanticide by females in mammals
Creators: name: Lukas, Dieter
name: Huchard, Elise
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: All drawings were downloaded from PhyloPic: http://phylopic.org; this file credits the specific authors
title: Zeitschrift des Allgemeinen Österreichischen Apothekervereines 25. Jahrgang 1887
title: Österreichische Zeitschrift für Pharmacie 41. Jahrgang
titleType: AlternativeTitle
Creators: name: :None
Publisher: name: Allgemeiner Österreichischer Apothekerverein
Year: 1887
Subjects: subject: 615

description: Zeitschrift des Allgemeinen Österreichischen Apothekervereines: 1. 1863 - 37. 1899, vol. 25. 1887