cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Multipole matrix elements of Green function of Laplace equation
Creators: name: Makuch, Karol
name: Górka, Przemysław
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Multipole matrix elements of Green function of Laplace equation are calculated. The multipole matrix elements of Green function in electrostatics describe potential on a sphere which is produced by a charge distributed on the surface of a different (possibly overlapping) sphere of the same radius. The matrix elements are defined by double convolution of two spherical harmonics with the Green function of Laplace equation. The method we use relies on the fact that in the Fourier space the double convolution has simple form. Therefore we calculate the multipole matrix from its Fourier transform. An important part of our considerations is simplification of the three dimensional Fourier transformation of general multipole matrix by its rotational symmetry to the one-dimensional Hankel transformation.
Evidence of heterogeneity in statin-associated type 2 diabetes mellitus risk: A meta-analysis of randomized controlled trials and observational studies
Creators: name: Keyserling, T.C.
name: Engeda, J.C.
name: Lhachimi, S.K.
name: Avery, C.L.
name: Rosamond, W.D.
name: White, M.
name: Stackhouse, A.
name: Lund, J.L.
Publisher: name: Elsevier Ireland Ltd
Year: 2019

description: Aims: To conduct a meta-analysis of statin-associated type 2 diabetes mellitus (T2D) risk among randomized controlled trials (RCTs) and observational studies (OBSs), excluding studies conducted among secondary prevention populations. Methods: Studies were identified by searching PubMed (1994-present) and EMBASE (1994-present). Articles had to meet the following criteria: (1) follow-up >one year; (2) >50% of participants free of clinically diagnosed ASCVD; (3) adult participants ≥30 years old; (4) reported statin-associated T2D effect estimates; and (5) quantified precision using 95% confidence interval. Data were pooled using random-effects model. Results: We identified 23 studies (35% RCTs) of n = 4,012,555 participants. OBS participants were on average younger (mean difference = 6.2 years) and had lower mean low-density lipoprotein cholesterol (LDL-C, mean difference = 20.6 mg/dL) and mean fasting plasma glucose (mean difference = 5.2 mg/dL) compared to RCT participants. There was little evidence for publication bias (P > 0.1). However, evidence of heterogeneity was observed overall and among OBSs and RCTs (P Cochran = <0.05). OBS designs, younger baseline mean ages, lower LDL-C concentrations, and high proportions of never or former smokers were significantly associated with increased statin-associated T2D risk. Conclusions: Potentially elevated statin-associated T2D risk in younger populations with lower LDL-C merits further investigation in light of evolving statin guidelines targeting primary prevention populations.
Supplementary Information for improved high-quality reference genome of red drum (Sciaenops ocellatus).
Creators: name: xiao, yongshuang
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 310305
subject: Marine and estuarine ecology (incl. marine ichthyology)

description: Supplementary Information for the title of improved high-quality reference genome of red drum (Sciaenops ocellatus).
The Balance Sheet of the Farming Sector, 1971
Creators: name: Evans, Carson D.
name: Warren, Forest G.
name: Allen, Philp T.
name: Smith, Alan G.
name: Reinsel, Robert D.
name: Evans, Carson D.
name: Warren, Forest G.
name: Allen, Philp T.
name: Smith, Alan G.
name: Reinsel, Robert D.
Publisher: name: Unknown
Year: 1971
Subjects: subject: Financial Economics
subject: Production Economics
subject: Balance sheet
subject: farm assets
subject: debt
subject: credit
subject: credit sources
subject: equity

description: Farm proprietors' assets totaled $318.9 billion on January 1, 1971, while farm debt outstanding totaled $61.1 billion, leaving equities of $257.8 billion. The ratio of farm debt to value of assets was 19.2 percent, up from 18.8 percent a year earlier. Advances in the values of farm real estate made up over half of 1970's $9.3 billion gain in farm asset value; higher value of machinery and motor vehicles largely accounted for remaining growth. Farm non-real estate debt grew $2.7 billion during 1970, compared with $1.1 billion for farm real estate debt. Farmers were reluctant to take long-term real estate loans at the prevailing high interest rates. Realized net farm income dropped to $15.6 billion-down 6.5 percent from 1969.
Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: The cohorts for heart and aging research in genomic epidemiology
Creators: name: Macfarlane, P.W.
name: Ford, I.
name: Soliman, E.Z.
name: North, K.E.
name: Kerr, K.F.
name: Wiggins, K.L.
name: Li-Gao, R.
name: Gudnason, V.
name: Mook-Kanamori, D.O.
name: Sofer, T.
name: Salomaa, V.
name: Reiner, A.P.
name: Stewart, J.D.
name: O'Donnell, C.J.
name: Méndez-Giráldez, R.
name: Laaksonen, M.A.
name: Bis, J.C.
name: Sun, F.
name: Avery, C.L.
name: Stricker, B.H.
name: Rosendaal, F.R.
name: Buckley, B.M.
name: Duan, Q.
name: Psaty, B.M.
name: Kors, J.A.
name: Rotter, J.I.
name: Brody, J.A.
name: Cupples, L.A.
name: Hofman, A.
name: Napier, M.D.
name: Floyd, J.S.
name: Van Duijn, C.
name: Smith, A.V.
name: De Mutsert, R.
name: Noordam, R.
name: Wilhelmsen, K.
name: Evans, D.S.
name: Stürmer, T.
name: Stilp, A.M.
name: Li, X.
name: Li, Y.
name: Uitterlinden, A.G.
name: Lin, H.J.
name: Broer, L.
name: Trompet, S.
name: Launer, L.J.
name: Wilson, J.G.
name: Li, J.
name: Chen, Y.-D.
name: Rice, K.M.
name: Taylor, K.D.
name: Busch, E.L.
name: Sotoodehnia, N.
name: Sitlani, C.M.
name: Seyerle, A.A.
name: Gogarten, S.M.
name: Cummings, S.R.
name: Laurie, C.C.
name: Lange, L.A.
name: Highland, H.M.
name: Kristiansson, K.
name: Liu, Y.
name: Porthan, K.
name: Isaacs, A.
name: Heckbert, S.R.
name: Peloso, G.M.
name: Vasan, R.S.
name: Harris, T.B.
name: Newton-Cheh, C.
name: Roach, J.
name: Whitsel, E.A.
name: Lee, C.R.
name: Jukema, J.W.
name: Kaplan, R.C.
Publisher: name: Nature Publishing Group
Year: 2018

description: Thiazide diuretics, commonly used antihypertensives, may cause QT interval (QT) prolongation, a risk factor for highly fatal and difficult to predict ventricular arrhythmias. We examined whether common single-nucleotide polymorphisms (SNPs) modified the association between thiazide use and QT or its component parts (QRS interval, JT interval) by performing ancestry-specific, trans-ethnic and cross-phenotype genome-wide analyses of European (66%), African American (15%) and Hispanic (19%) populations (N=78 199), leveraging longitudinal data, incorporating corrected standard errors to account for underestimation of interaction estimate variances and evaluating evidence for pathway enrichment. Although no loci achieved genome-wide significance (P<5 × 10 -8 m), we found suggestive evidence (P<5 × 10 -6 ) for SNPs modifying the thiazide-QT association at 22 loci, including ion transport loci (for example, NELL1, KCNQ3). The biologic plausibility of our suggestive results and simulations demonstrating modest power to detect interaction effects at genome-wide significant levels indicate that larger studies and innovative statistical methods are warranted in future efforts evaluating thiazide-SNP interactions.
Importance of two current model in understanding the electronic transport behavior of inverse Heusler alloy: Fe 2 CoSi
Creators: name: Sharma, Sonu
name: Pandey, Sudhir K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Here we explore the applicability of the two current model in understanding the transport behavior of Fe 2 CoSi compound by using the first principles calculations in combination with the Boltzmann transport theory. The spin-unpolarized calculation shows large density of states (DOS) at Fermi level (E F) and is unable to provide the correct temperature dependence of transport coefficients. The spin-polarised calculation shows reduced DOS at the E F in the spin-up channel, whereas spin-dn channel have almost zero DOS at the E F . The absolute value of Seebeck coefficient in the spin-up channel shows linear increment with the temperature and in the spin-dn channel it varies non-linearly. The electrical conductivity also shows non-linear temperature dependence in both the spin channels whereas, the electronic thermal conductivity shows linear temperature dependence. The values of transport coefficients and their temperature dependence obtained by using the two current model are found to be in fairly good agreement with the experimental data. Present work clearly suggests the importance of two current model in understanding the transport properties of the compound.
description: 6 figures
On the Performance of Single- and Multi-carrier Modulation Schemes for Indoor Visible Light Communication Systems
Creators: name: Aminikashani, Mohammadreza
name: Kavehrad, Mohsen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this paper, we investigate and compare the performance of single- and multi-carrier modulation schemes for indoor visible light communication (VLC). Particularly, the performances of single carrier frequency domain equalization (SCFDE), orthogonal frequency division multiplexing (OFDM) and on-off keying (OOK) with minimum mean square error equalization (MMSE) are analyzed in order to mitigate the effect of multipath distortion of the indoor optical channel where nonlinearity distortion of light emitting diode (LED) transfer function is taken into account. Our results indicate that SCFDE system, in contrast to OFDM system, does not suffer from high peak to average power ratio (PAPR) and can outperform OFDM and OOK systems. We further investigate the impact of LED bias point on the performance of OFDM systems and show that biasing LED with the optimum value can significantly enhance the performance of the system. Bit-interleaved coded modulation (BICM) is also considered for OFDM and SCFDE systems to further compensate signal degradation due to inter-symbol interference (ISI) and LED nonlinearity.
description: 6 Pages, IEEE Globecom conference 2014
Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group
Creators: name: Launer, L.J.
name: Busch, E.L.
name: Soliman, E.Z.
name: Napier, M.D.
name: Mook-Kanamori, D.O.
name: Gogarten, S.M.
name: De Mutsert, R.
name: Stott, D.J.
name: Laurie, C.C.
name: Kerr, K.F.
name: Sotoodehnia, N.
name: Jukema, J.W.
name: Floyd, J.S.
name: Kors, J.A.
name: Eicher, J.D.
name: Chen, Y.-D.
name: Kaplan, R.C.
name: Whitsel, E.A.
name: Harris, T.B.
name: Heckbert, S.R.
name: Stewart, J.D.
name: Johnson, A.D.
name: Bis, J.C.
name: Broer, L.
name: Rice, K.M.
name: Roach, J.
name: Li, X.
name: Sitlani, C.M.
name: Duan, Q.
name: Evans, D.S.
name: Stürmer, T.
name: Wiggins, K.L.
name: Wilson, J.G.
name: Smith, A.V.
name: Méndez-Giráldez, R.,
name: Uitterlinden, A.G.
name: Psaty, B.M.
name: Stricker, B.H.
name: Avery, C.L.
name: Seyerle, A.A.
name: Lin, H.J.
name: Gudnason, V.
name: Rosendaal, F.R.
name: Brody, J.A.
name: Li, Y.
name: Cupples, L.A.
name: Wilhelmsen, K.C.
name: Taylor, K.D.
name: Rotter, J.I.
name: Li, J.
name: Slagboom, P.E.
name: Cummings, S.R.
name: Trompet, S.
name: Noordam, R.
name: Sattar, N.
name: Liu, Y.
name: Lange, L.A.
name: Li-Gao, R.
name: Reiner, A.P.
Publisher: name: Nature Publishing Group
Year: 2018

description: Sulfonylureas, a commonly used class of medication used to treat type 2 diabetes, have been associated with an increased risk of cardiovascular disease. Their effects on QT interval duration and related electrocardiographic phenotypes are potential mechanisms for this adverse effect. In 11 ethnically diverse cohorts that included 71 857 European, African-American and Hispanic/Latino ancestry individuals with repeated measures of medication use and electrocardiogram (ECG) measurements, we conducted a pharmacogenomic genome-wide association study of sulfonylurea use and three ECG phenotypes: QT, JT and QRS intervals. In ancestry-specific meta-analyses, eight novel pharmacogenomic loci met the threshold for genome-wide significance (P<5 × 10 ' '8), and a pharmacokinetic variant in CYP2C9 (rs1057910) that has been associated with sulfonylurea-related treatment effects and other adverse drug reactions in previous studies was replicated. Additional research is needed to replicate the novel findings and to understand their biological basis.
Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy
Creators: name: Bartz, T.M.
name: Taylor, K.D.
name: Highland, H.M.
name: Wilhelmsen, K.C.
name: Brody, J.A.
name: Liao, D.
name: Yao, J.
name: Guo, X.
name: Zhang, Z.-M.
name: Avery, C.L.
name: Psaty, B.M.
name: Sitlani, C.M.
name: Roach, J.
name: Méndez-Giráldez, R.
name: Gondalia, R.
name: Tinker, L.F.
name: Lin, H.J.
name: Whitsel, E.A.
name: Franceschini, N.
name: Gogarten, S.M.
name: Seyerle, A.A.
name: Stewart, J.D.
name: Yan, S.
name: Duan, Q.
name: Napier, M.D.
name: Rotter, J.I.
name: Li, Y.
name: Laurie, C.C.
name: Reiner, A.P.
name: Heckbert, S.R.
name: Sotoodehnia, N.
name: North, K.E.
name: Soliman, E.Z.
Publisher: name: Nature Publishing Group
Year: 2018

description: The genetic basis of supraventricular and ventricular ectopy (SVE, VE) remains largely uncharacterized, despite established genetic mechanisms of arrhythmogenesis. To identify novel genetic variants associated with SVE/VE in ancestrally diverse human populations, we conducted a genome-wide association study of electrocardiographically identified SVE and VE in five cohorts including approximately 43,000 participants of African, European and Hispanic/Latino ancestry. In thirteen ancestry-stratified subgroups, we tested multivariable-adjusted associations of SVE and VE with single nucleotide polymorphism (SNP) dosage. We combined subgroup-specific association estimates in inverse variance-weighted, fixed-effects and Bayesian meta-analyses. We also combined fixed-effects meta-analytic t-test statistics for SVE and VE in multi-trait SNP association analyses. No loci reached genome-wide significance in trans-ethnic meta-analyses. However, we found genome-wide significant SNPs intronic to an apoptosis-enhancing gene previously associated with QRS interval duration (FAF1; lead SNP rs7545860; effect allele frequency = 0.02; P = 2.0 × 10-8) in multi-trait analysis among European ancestry participants and near a locus encoding calcium-dependent glycoproteins (DSC3; lead SNP rs8086068; effect allele frequency = 0.17) in meta-analysis of SVE (P = 4.0 × 10-8) and multi-trait analysis (P = 2.9 × 10-9) among African ancestry participants. The novel findings suggest several mechanisms by which genetic variation may predispose to ectopy in humans and highlight the potential value of leveraging pleiotropy in future studies of ectopy-related phenotypes.
Fluctuation driven topological transition of binary condensates in optical lattices
Creators: name: Suthar, K.
name: Roy, Arko
name: Angom, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We show the emergence of a third Goldstone mode in binary condensates at the phase-separation in quasi-1D optical lattices. We develop the coupled discrete nonlinear Schrödinger equations (DNLSEs) using Hartree-Fock-Bogoliubov theory with Popov approximation in the Bose-Hubbard model to investigate the mode evolution at zero temperature. In particular, as the system is driven from miscible to immiscible phase. We demonstrate that the position swapping of the species in $^{87}$Rb-$^{85}$Rb system is accompanied by a discontinuity in the excitation spectrum. Our results show that in quasi-1D optical lattices, the presence of the fluctuations dramatically change the geometry of the ground state density profile of TBEC.
description: 10 pages, 8 figures
Cardiovascular genetic risk testing for targeting statin therapy in the primary prevention of atherosclerotic cardiovascular disease
Creators: name: Weinberger, M.
name: Jarmul, J.
name: Lich, K.H.
name: Wheeler, S.B.
name: Earnshaw, S.
name: Pignone, M.
name: Jonas, D.E.
name: Avery, C.L.
name: Pletcher, M.J.
Publisher: name: Lippincott Williams and Wilkins
Year: 2018

description: Background: It is unclear whether testing for novel risk factors, such as a cardiovascular genetic risk score (cGRS), improves clinical decision making or health outcomes when used for targeting statin initiation in the primary prevention of atherosclerotic cardiovascular disease (ASCVD). Our objective was to estimate the cost-effectiveness of cGRS testing to inform clinical decision making about statin initiation in individuals with low-to-intermediate (2.5%-7.5%) 10-year predicted risk of ASCVD. Methods and Results: We evaluated the cost-effectiveness of testing for a 27-single-nucleotide polymorphism cGRS comparing 4 test/treat strategies: Treat all, treat none, test/treat if cGRS is high, and test/treat if cGRS is intermediate or high. We tested a set of clinical scenarios of men and women, aged 45 to 65 years, with 10-year ASCVD risks between 2.5% and 7.5%. Our primary outcome measure was cost per quality-adjusted life-year gained. Under base case assumptions for statin disutility and cost, the preferred strategy is to treat all patients with ASCVD risk >2.5% without cGRS testing. For certain clinical scenarios, such as a 57-year-old man with a 10-year ASCVD risk of 7.5%, cGRS testing can be cost-effective under a limited set of assumptions; for example, when statins cost $15 per month and statin disutility is 0.013 (ie, willing to trade 3 months of life in perfect health to avoid 20 years of statin therapy), the preferred strategy (using a willingness-to-pay threshold of $50 000 per quality-adjusted life-year gained) is to test and treat if cGRS is intermediate or high. Overall, the results were not sensitive to assumptions about statin efficacy and harms. Conclusions: Testing for a 27-single-nucleotide polymorphism cGRS is generally not a cost-effective approach for targeting statin therapy in the primary prevention of ASCVD for low- to intermediate-risk patients.
A novel formula for plastic hinge length of reinforced concrete columns in seismic regions
Creators: name: Wei, Wang
name: Shao, Changjiang
name: Huang, Hui
name: Zhuang, Weilin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: The plastic hinge region length is the critical parameter to determine the deformation capacity of a reinforced concrete (RC) column. The foregoing researches showed that many factores should be included to accurately access the length of plastic hinge, which could be found in the existing formulas. However, the effect of the tension shift of longitudinal rebar was not paid enough attention in these publications. In order to consider the tension shift effect, a novel model of the plastic hinge length was established based upon the equivalent principle of plastic rotation. The quasi-static tests of seven RC columns were carried out to quantify the undetermined parameters in the proposed formula. To eveluate the rationallity of the suggested model, several existing formulas were applied to calculate the plastic hinge length of the tested columns. The comparison between test and calculation shows that the proposed model can predict more accurately the hinge length of 30 columns in the literature with less discreteness than the existing formulas.
The Balance Sheet of the Farming Sector, 1972
Creators: name: Evans, Carson D.
name: Warren, Forest G.
name: Reinsel, Robert D.
name: Evans, Carson D.
name: Warren, Forest G.
name: Reinsel, Robert D.
Publisher: name: Unknown
Year: 1973
Subjects: subject: Financial Economics
subject: Production Economics
subject: Balance sheet
subject: farm assets
subject: debt
subject: credit sources
subject: equity

description: The value of farm assets (excluding Alaska and Hawaii) amounted to $339.2 billion on January 1, 1972. Debts totaled $66.9 billion, leaving equity of $272.3 billion. The debt-to-asset ratio increased slightly to 19.7 percent. Two-thirds of the $24.3 billion increase in asset value during 1971 was due to a record $15.6-billion increase in the value of farm real estate. Most of the remaining third was due to increases in the value of livestock and machinery and motor vehicles. Farm debt increased a record $5.8 billion. About two-thirds of the increase was in non-real estate debt and the other third was in farm mortgages. Interest charges on farm debt in 1971 totaled $3.9 billion, up $0.2 billion from 1970. Total realized net farm income of farm operators in the 48 contiguous States dropped to $16.0 billion from $16.8 billion in 1970; realized net farm income per farm slipped from $5,740 to $5,560.
An application of unrelated parallel machine scheduling with sequence-dependent setups at Vestel Electronics
Creators: name: Elyasi, Milad
name: Ekici, Ali
name: Örsan Özener, Okan
name: Sarıkaya, Merve Burcu
Publisher: name: figshare
Year: 2022
Subjects: subject: 91005 Manufacturing Management
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In this paper, we analyze a variant of the unrelated parallel machine scheduling problem with the objective of minimizing the total tardiness and earliness in the presence of sequence-dependent setups, unequal release times, machine-job compatibility restrictions and workload balance requirements. This study is motivated by the production scheduling operations at a television manufacturer, Vestel Electronics. Vestel produces LCD/LED TVs and has a significant market share in the consumer electronics sector in Europe. TV manufacturing is planned based on a make-to-order strategy, and Vestel uses 15 assembly lines to produce 110 different product groups and 3817 different models. Once the orders are received, production scheduling is performed at the beginning of each month, and the goal is to satisfy the demand on time as much as possible. The decision maker has to consider several factors including job-assembly line compatibility, the release and due dates of the jobs and a workload balance among different assembly lines when forming the production schedule. To address this problem, we propose a wide range of heuristics including (i) a sequential algorithm, (ii) a tabu search algorithm, (iii) a random set partitioning approach, and (iv) a novel matheuristic approach utilizing the local intensification and global diversification powers of a tabu search algorithm. Through a computational study, we observe that all the proposed approaches not only significantly outperform the current practice but also provide solutions with around 5% less optimality gap compared to a benchmark algorithm in the literature.
Search for the Standard Model Higgs boson produced in association with top quarks and decaying into $b\bar{b}$ in pp collisions at $\sqrt{s}$ = 8 TeV with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for the Standard Model Higgs boson produced in association with a pair of top quarks, $t\bar{t}H$, is presented. The analysis uses 20.3 fb$^{-1}$ of pp collision data at $\sqrt{s}$ = 8 TeV, collected with the ATLAS detector at the Large Hadron Collider during 2012. The search is designed for the H to $b\bar{b}$ decay mode and uses events containing one or two electrons or muons. In order to improve the sensitivity of the search, events are categorised according to their jet and b-tagged jet multiplicities. A neural network is used to discriminate between signal and background events, the latter being dominated by $t\bar{t}$+jets production. In the single-lepton channel, variables calculated using a matrix element method are included as inputs to the neural network to improve discrimination of the irreducible $t\bar{t}$+$b\bar{b}$ background. No significant excess of events above the background expectation is found and an observed (expected) limit of 3.4 (2.2) times the Standard Model cross section is obtained at 95% confidence level. The ratio of the measured $t\bar{t}H$ signal cross section to the Standard Model expectation is found to be $μ$ = 1.5 $\pm$ 1.1 assuming a Higgs boson mass of 125 GeV.
description: 41 pages plus author list plus cover page (52 pages total), 34 figures, 11 tables, submitted to Eur. Phys. J. C, All figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HIGG-2013-27/
On the Dynamics of Ultra Compact X-ray Binaries: 4U 1850-087, 4U 0513-40 and M15 X-2
Creators: name: Prodan, Snezana
name: Murray, Norman
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In this work we extend our dynamical study of Ultra Compact X-ray Binaries (UCXB) 4U 1820-30 from Prodan and Murray 2012 to three more UCXBs in globular clusters: 4U 1850-087, 4U 0513-40 and M15 X-2. These three UCXBs have orbital periods < 20 mins. Two of them, 4U 1850-087 and 4U 0513-40, have suspected luminosity variations of order of ~ 1yr. There is insufficient observational data to make any statements regarding the long periodicity in the light curve of M15 X-2 at this point. The properties of these three systems are quite similar to 4U 1820-30, which prompt us to model their dynamics in the same manner. As in the case of 4U 1820-30, we interpret the suspected long periods as the period of small oscillations around a stable fixed point in the Kozai resonance. We provide a lower limit on the tidal dissipation factor Q which is in agreement with results obtained for the case of 4U 1820-30.
description: ApJ accepted, 11 pages, 13 figures
An application of unrelated parallel machine scheduling with sequence-dependent setups at Vestel Electronics
Creators: name: Ekici, Ali
name: Elyasi, Milad
name: Örsan Özener, Okan
name: Sarıkaya, Merve Burcu
Publisher: name: figshare
Year: 2022
Subjects: subject: 91005 Manufacturing Management
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In this paper, we analyze a variant of the unrelated parallel machine scheduling problem with the objective of minimizing the total tardiness and earliness in the presence of sequence-dependent setups, unequal release times, machine-job compatibility restrictions and workload balance requirements. This study is motivated by the production scheduling operations at a television manufacturer, Vestel Electronics. Vestel produces LCD/LED TVs and has a significant market share in the consumer electronics sector in Europe. TV manufacturing is planned based on a make-to-order strategy, and Vestel uses 15 assembly lines to produce 110 different product groups and 3817 different models. Once the orders are received, production scheduling is performed at the beginning of each month, and the goal is to satisfy the demand on time as much as possible. The decision maker has to consider several factors including job-assembly line compatibility, the release and due dates of the jobs and a workload balance among different assembly lines when forming the production schedule. To address this problem, we propose a wide range of heuristics including (i) a sequential algorithm, (ii) a tabu search algorithm, (iii) a random set partitioning approach, and (iv) a novel matheuristic approach utilizing the local intensification and global diversification powers of a tabu search algorithm. Through a computational study, we observe that all the proposed approaches not only significantly outperform the current practice but also provide solutions with around 5% less optimality gap compared to a benchmark algorithm in the literature.
title: Cones of orthogonal Shimura subvarieties and equidistribution
Creators: name: Zuffetti, Riccardo
Publisher: name: Springer
Year: 2025

description: Let X be an orthogonal Shimura variety, and let Cᵣᵒʳᵗ(X) be the cone generated by the cohomology classes of orthogonal Shimura subvarieties in X of dimension r. We investigate the asymptotic properties of the generating rays of Cᵣᵒʳᵗ(X) for large values of r. They accumulate towards rays generated by wedge products of the Kähler class of X and the fundamental class of an orthogonal Shimura subvariety. We also compare Cᵣᵒʳᵗ(X) with the cone generated by the special cycles of dimension r. The main ingredient to achieve the results above is the equidistribution of orthogonal Shimura subvarieties.
GWAS of QRS duration identifies new loci specific to Hispanic/Latino populations
Creators: name: Thornton, T.A.
name: Kerr, K.F.
name: Cheng, S.
name: Soliman, E.Z.
name: Hanis, C.L.
name: Sotoodehnia, N.
name: Taylor, K.D.
name: Lin, H.J.
name: Below, J.E.
name: Heckbert, S.R.
name: Sofer, T.
name: Laurie, C.C.
name: Swenson, B.R.
name: McKnight, B.
name: Evans, D.S.
name: Avery, C.L.
name: Seyerle, A.A.
name: Méndez-Giráldez, R.
name: Guo, X.
name: Petty, L.E.
name: Kooperberg, C.
name: Rotter, J.I.
name: Darbar, D.
name: Highland, H.
name: Yao, J.
name: Ryckman, K.K.
name: Louie, T.
name: Whitsel, E.A.
name: Nalls, M.A.
name: Bello, N.A.
Publisher: name: Public Library of Science
Year: 2018

description: Background The electrocardiographically quantified QRS duration measures ventricular depolarization and conduction. QRS prolongation has been associated with poor heart failure prognosis and cardiovascular mortality, including sudden death. While previous genome-wide association studies (GWAS) have identified 32 QRS SNPs across 26 loci among European, African, and Asian-descent populations, the genetics of QRS among Hispanics/Latinos has not been previously explored. Methods We performed a GWAS of QRS duration among Hispanic/Latino ancestry populations (n = 15,124) from four studies using 1000 Genomes imputed genotype data (adjusted for age, sex, global ancestry, clinical and study-specific covariates). Study-specific results were combined using fixed-effects, inverse variance-weighted meta-analysis. Results We identified six loci associated with QRS (P<5x10-8), including two novel loci: MYOCD, a nuclear protein expressed in the heart, and SYT1, an integral membrane protein. The top SNP in the MYOCD locus, intronic SNP rs16946539, was found in Hispanics/Latinos with a minor allele frequency (MAF) of 0.04, but is monomorphic in European and African descent populations. The most significant QRS duration association was with intronic SNP rs3922344 (P = 1.19x10-24) in SCN5A/SCN10A. Three other previously identified loci, CDKN1A, VTI1A, and HAND1, also exceeded the GWAS significance threshold among Hispanics/Latinos. A total of 27 of 32 previously identified QRS duration SNPs were shown to generalize in Hispanics/Latinos. Conclusions Our QRS duration GWAS, the first in Hispanic/Latino populations, identified two new loci, underscoring the utility of extending large scale genomic studies to currently under-examined populations.
Genome-wide association study of PR interval in Hispanics/Latinos identifies novel locus at ID2
Creators: name: Sotoodehnia, N.
name: Soliman, E.
name: Guo, X.
name: Yao, J.
name: Méndez Giráldez, R.
name: Rodriguez, C.
name: Kooperberg, C.
name: Rotter, J.I.
name: Kerr, K.F.
name: Lin, H.J.
name: Taylor, K.D.
name: Baldassari, A.
name: Laurie, C.C.
name: Avery, C.L.
name: Graff, M.
name: Whitsel, E.A.
name: Heckbert, S.
name: Seyerle, A.A.
name: Stilp, A.
name: Gogarten, S.M.
Publisher: name: BMJ Publishing Group
Year: 2018

description: Objective: PR interval (PR) is a heritable electrocardiographic measure of atrial and atrioventricular nodal conduction. Changes in PR duration may be associated with atrial fibrillation, heart failure and all-cause mortality. Hispanic/Latino populations have high burdens of cardiovascular morbidity and mortality, are highly admixed and represent exceptional opportunities for novel locus identification. However, they remain chronically understudied. We present the first genome-wide association study (GWAS) of PR in 14 756 participants of Hispanic/Latino ancestry from three studies. Methods: Study-specific summary results of the association between 1000 Genomes Phase 1 imputed single-nucleotide polymorphisms (SNPs) and PR assumed an additive genetic model and were adjusted for global ancestry, study centre/region and clinical covariates. Results: were combined using fixed-effects, inverse variance weighted meta-analysis. Sequential conditional analyses were used to identify independent signals. Replication of novel loci was performed in populations of Asian, African and European descent. ENCODE and RoadMap data were used to annotate results. Results: We identified a novel genome-wide association (P<5×10 -8) with PR at ID2 (rs6730558), which replicated in Asian and European populations (P<0.017). Additionally, we generalised 10 previously identified PR loci to Hispanics/Latinos. Bioinformatics annotation provided evidence for regulatory function in cardiac tissue. Further, for six loci that generalised, the Hispanic/Latino index SNP was genome-wide significant and identical to (or in high linkage disequilibrium with) the previously identified GWAS lead SNP. Conclusions: Our results suggest that genetic determinants of PR are consistent across race/ethnicity, but extending studies to admixed populations can identify novel associations, underscoring the importance of conducting genetic studies in diverse populations.
Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study
Creators: name: Cheng, I.
name: Reiner, A.P.
name: Ballantyne, C.M.
name: Heiss, G.
name: Assimes, T.L.
name: LaCroix, A.Z.
name: Nishimura, K.
name: Barbalic, M.
name: Marchand, L.L.
name: Kooperberg, C.
name: Talavera, G.A.
name: Bůžková, P.
name: Carlson, C.
name: Best, L.G.
name: Bien, S.
name: Carty, C.L.
name: Haiman, C.A.
name: Avery, C.L.
name: Tang, W.
name: Peters, U.
name: Ambite, J.L.
name: Fornage, M.
name: North, K.E.
name: Pankratz, N.
name: Crawford, D.C.
name: Tao, R.
name: Haessler, J.
name: Graff, M.
name: Richard, M.
name: Chirinos-Medina, D.A.
name: Kocarnik, J.M.
name: Hindorff, L.A.
name: Pereira, R.
name: Daviglus, M.L.
name: Chen, D.
Publisher: name: Oxford University Press
Year: 2018

description: C-reactive protein (CRP) is a circulating biomarker indicative of systemic inflammation. We aimed to evaluate genetic associations with CRP levels among non-European-ancestry populations through discovery, fine-mapping and conditional analyses. A total of 30 503 non-European-ancestry participants from 6 studies participating in the Population Architecture using Genomics and Epidemiology study had serum high-sensitivity CRP measurements and ~200 000 single nucleotide polymorphisms (SNPs) genotyped on the Metabochip. We evaluated the association between each SNP and log-transformed CRP levels using multivariate linear regression, with additive genetic models adjusted for age, sex, the first four principal components of genetic ancestry, and study-specific factors. Differential linkage disequilibrium patterns between race/ ethnicity groups were used to fine-map regions associated with CRP levels. Conditional analyses evaluated for multiple independent signals within genetic regions. One hundred and sixty-three unique variants in 12 loci in overall or race/ ethnicity-stratified Metabochip-wide scans reached a Bonferroni-corrected P-value<2.5E-7. Three loci have no (HACL1, OLFML2B) or only limited (PLA2G6) previous associations with CRP levels. Six loci had different top hits in race/ethnicityspecific versus overall analyses. Fine-mapping refined the signal in six loci, particularly in HNF1A. Conditional analyses provided evidence for secondary signals in LEPR, IL1RN and HNF1A, and for multiple independent signals in CRP and APOE. We identified novel variants and loci associated with CRP levels, generalized known CRP associations to a multiethnic study population, refined association signals at several loci and found evidence for multiple independent signals at several well-known loci. This study demonstrates the benefit of conducting inclusive genetic association studies in large multiethnic populations.
Reform der deutschen Hinzurechnungsbesteuerung – Reichweite und Ausgestaltung des Motivtests
Creators: name: Zilch, Léon
Publisher: name: Universität Kassel
Year: 2022
Subjects: subject: Hinzurechnungsbesteuerung
subject: Motivtest
subject: Europäisches Steuerrecht
subject: Europarecht
subject: Internationales Steuerrecht
subject: Niederlassungsfreiheit
subject: Kapitalverkehrsfreiheit
subject: 340
subject: Hinzurechnung
subject: Außensteuerrecht
subject: Europarecht
subject: Internationales Steuerrecht
subject: Niederlassungsfreiheit
subject: Kapitalverkehrsfreiheit

description: Zugleich: Dissertation, Universität Kassel, 2022
The Balance Sheet of the Farming Sector, 1973
Creators: name: Evans, Carson D.
name: Warren, Forest G.
name: Reinsel, Robert D.
name: Simunek, Richard W.
name: Evans, Carson D.
name: Warren, Forest G.
name: Reinsel, Robert D.
name: Simunek, Richard W.
Publisher: name: Unknown
Year: 1973
Subjects: Financial Economics
Production Economics

description: The value of farm assets totaled $385.5 billion January 1,1973, after increasing $42.4 billion during 1972. The 12.5 percent rise since the beginning of 1972 was much sharper than the 7.8 percent increase during 1971 and four times the modest 3.0 percent growth in 1970. Farm debt including CCC loans reached $73.6 billion at the beginning of 1973, a growth of $6.7 billion. The 10.0 percent increase in 1972 was only slightly higher than in 1971 but twice the growth rate of 1970. Equity owned by farm proprietors amounted to $309.9 billion January 1, 1973, posting a $35.7 billion increase over a year earlier. The 13.0 percent hike almost doubled the 1971 rise and was nearly four times the percentage increase during 1970.
On the existence of unimodular elements and cancellation of projective modules over noetherian and non-noetherian rings
Creators: name: Gupta, Anjan
Publisher: name: arXiv
Year: 2014
Subjects: subject: K-Theory and Homology (math.KT)
subject: FOS: Mathematics

description: Let $R$ be a commutative ring of dimension $d$, $S = R[X]$ or $R[X, 1/X]$ and $P$ a finitely generated projective $S$ module of rank $r$. Then $P$ is cancellative if $P$ has a unimodular element and $r \geq d + 1$. Moreover if $r \geq \dim (S)$ then $P$ has a unimodular element and therefore $P$ is cancellative. As an application we have proved that if $R$ is a ring of dimension $d$ of finite type over a Prüfer domain and $P$ is a projective $R[X]$ or $R[X, 1/X]$ module of rank at least $d + 1$, then $P$ has a unimodular element and is cancellative.
description: 21 pages
PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data from 9 Studies of Blacks and Whites
Creators: name: Postmus, I.
name: Muntner, P.
name: Howard, G.
name: Harris, T.B.
name: Li, X.
name: Levitan, E.B.
name: Stewart, J.D.
name: Avery, C.L.
name: Cummings, S.R.
name: Liu, Y.
name: Evans, D.S.
name: Safford, M.M.
name: Sitlani, C.M.
name: Trompet, S.
name: Lange, L.
name: Gudnason, V.
name: Wilson, J.G.
name: Smith, A.V.
name: Correa, A.
name: Judd, S.E.
name: Cushman, M.
name: Post, W.S.
name: Wiggins, K.L.
name: Whitsel, E.A.
name: Woolley, J.M.
name: Kent, S.T.
name: Psaty, B.M.
name: Irvin, M.R.
name: Chen, Y.-D.I.
name: Cupples, L.A.
name: Rotter, J.I.
name: Rosenson, R.S.
name: Sun, F.
name: Vasan, R.S.
name: Jukema, J.W.
Publisher: name: Lippincott Williams and Wilkins
Year: 2017

description: PCSK9 loss-of-function (LOF) variants allow for the examination of the effects of lifetime reduced low-density lipoprotein cholesterol (LDL-C) on cardiovascular events. We examined the association of PCSK9 LOF variants with LDL-C and incident coronary heart disease and stroke through a meta-analysis of data from 8 observational cohorts and 1 randomized trial of statin therapy. Methods and Results - These 9 studies together included 17 459 blacks with 403 (2.3%) having at least 1 Y142X or C679X variant and 31 306 whites with 955 (3.1%) having at least 1 R46L variant. Unadjusted odds ratios for associations between PCSK9 LOF variants and incident coronary heart disease (851 events in blacks and 2662 events in whites) and stroke (523 events in blacks and 1660 events in whites) were calculated using pooled Mantel-Haenszel estimates with continuity correction factors. Pooling results across studies using fixed-effects inverse-variance-weighted models, PCSK9 LOF variants were associated with 35 mg/dL (95% confidence interval [CI], 32-39) lower LDL-C in blacks and 13 mg/dL (95% CI, 11-16) lower LDL-C in whites. PCSK9 LOF variants were associated with a pooled odds ratio for coronary heart disease of 0.51 (95% CI, 0.28-0.92) in blacks and 0.82 (95% CI, 0.63-1.06) in whites. PCSK9 LOF variants were not associated with incident stroke (odds ratio, 0.84; 95% CI, 0.48-1.47 in blacks and odds ratio, 1.06; 95% CI, 0.80-1.41 in whites). Conclusions - PCSK9 LOF variants were associated with lower LDL-C and coronary heart disease incidence. PCSK9 LOF variants were not associated with stroke risk.
Fitting BICEP2 with defects, primordial gravitational waves and dust
Creators: name: Lizarraga, Joanes
name: Urrestilla, Jon
name: Daverio, David
name: Hindmarsh, Mark
name: Kunz, Martin
name: Liddle, Andrew R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this work we discuss the possibility of cosmic defects being responsible for the B-mode signal measured by the BICEP2 collaboration. We also allow for the presence of other cosmological sources of B-modes such as inflationary gravitational waves and polarized dust foregrounds, which might contribute to or dominate the signal. On the one hand, we find that defects alone give a poor fit to the data points. On the other, we find that defects help to improve the fit at higher multipoles when they are considered alongside inflationary gravitational waves or polarized dust. Finally, we derive new defect constraints from models combining defects and dust. This proceeding is based on previous works [1,2].
description: 6 pages and 3 figures. Prepared for the Spanish Relativity Meetings ERE2014
What makes domain knowledge difficult? Word usage frequency from SUBTLEX and dlexDB explains knowledge item difficulty
Creators: name: Ludewig, Ulrich
name: Alscher, Pascal
name: Chen, Xiaobin
name: McElvany, Nele
Publisher: name: TU Dortmund
Year: 2022
Subjects: subject: Political knowledge
subject: Word frequency
subject: Item difficulty
subject: Statistical suppression effect
subject: Educational assessment
subject: 370
subject: Politische Bildung
subject: Worthäufigkeit
subject: Sprache
subject: Testergebnis

description: The quality of tests in psychological and educational assessment is of great scholarly and public interest. Item difficulty models are vital to generating test result interpretations based on evidence. A major determining factor of item difficulty in knowledge tests is the opportunity to learn about the facts and concepts in question. Knowledge is mainly conveyed through language. Exposure to language associated with facts and concepts might be an indicator of the opportunity to learn. Thus, we hypothesize that item difficulty in knowledge tests should be related to the probability of exposure to the item content in everyday life and/or academic settings and therefore also to word frequency. Results from a study with 99 political knowledge test items administered to N = 250 German seventh (age: 11–14 years) and tenth (age: 15–18 years) graders showed that word frequencies in everyday settings (SUBTLEX-DE) explain variance in item difficulty, while word frequencies in academic settings (dlexDB) alone do not. However, both types of word frequency combined explain a considerable amount of the variance in item difficulty. Items with words that are more frequent in both settings and, in particular, relatively frequent in everyday settings are easier. High word frequencies and relatively higher word frequency in everyday settings could be associated with higher probability of exposure, conceptual complexity, and better readability of item content. Examining word frequency from different language settings can help researchers investigate test score interpretations and is a useful tool for predicting item difficulty and refining knowledge test items.
description: Behavior research methods;55(5)
The Balance Sheet of the Farming Sector, 1974
Creators: name: Evans, Carson D.
name: Simunek, Richard W.
name: Allen, Philp T.
name: Reinsel, Robert D.
name: Evans, Carson D.
name: Simunek, Richard W.
name: Allen, Philp T.
name: Reinsel, Robert D.
Publisher: name: Unknown
Year: 1974
Subjects: Financial Economics
Production Economics

description: On January 1, 1974, farm proprietors owned equity totaling $394.7 billion in assets worth $478.8 billion after deducting $84.1 billion in farm debt. Increases in equity ($82.8 billion) and asset value ($92.0 billion) from January 1, 1973, were records, far outstripping any other yearly gains. Over two-thirds ($64.7 billion) of the increase in assets was due to a record 25-percent gain in real estate value, but livestock and crop values also increased rapidly mainly because of higher prices. Farm debt outstanding January 1, 1974, was $9.2 billion above January 1, 1973, with real estate increasing more rapidly than nonreal estate debt. Interest charges of $5.1 billion on farm debt in 1973 were sharply higher—18 percent—than in 1972, reflecting both the increased use of credit and higher interest rates. The 17.6-percent ratio of farm debt to value of assets on January 1, 1974, was down sharply from the 19.4-percent ratio on January 1, 1973, and was the second consecutive decrease since the ratio began a steady climb in 1958. The rapid rises in asset value and more moderate rises in farm debt during 1972 and 1973 caused the ratio to drop. Returns to equity in farm production assets jumped to 10.9 percent for 1973 from 4.7 percent in 1972, reflecting the faster rate of increase in gross farm income than in production expenses. Beginning with 1969, The Balance Sheet of the Farming Sector includes data for Alaska and Hawaii; formerly estimates were available for only the 48 contiguous States.
title: Mitteilungen des Kunsthistorischen Institutes in Florenz, Bd. 43 Nr. 1 (1999): Mitteilungen des Kunsthistorischen Institutes in Florenz
title: Mitteilungen des Kunsthistorischen Institutes in Florenz
titleType: AlternativeTitle
Creators: name: Mitteilungen Des Kunsthistorischen Institutes In Florenz
Publisher: name: Mitteilungen des Kunsthistorischen Institutes in Florenz
Year: 2024

description: Band XLIII, Heft 1 (1999)
description: Bartolomeo Ammannati e le statue degli Apostoli in Santa Maria del Fiore: ipotesi e acquisizioni documentarie...208-224
Die Statuen der berühmten Toskaner im Hof der Uffizien...103-188
L’Incoronazione della Vergine nella controfacciata della cattedrale di Santa Maria del Fiore e altri mosaici monumentali in Toscana...14-48
Ein Lehrender Christus von Nicola Pisano im Zisterzienserinnen­kloster St. Marienstern in Sachsen...1-13
Abkürzungsschlüssel...XXXIX-XLV
Verzeichnisse...VII-XXXVIII
Inhalt | Contenuto
Titelei