cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Public-Private Partnerships for Increasing Investment in Preservation
Creators: name: Anderson, DeWayne H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: The purpose of this paper is to describe the motivations of investors, the obstacles to attracting investment to preservation ventures, public development needs addressed by preservation, financing tools available for housing rehabilitation, and the benefits of public-private partnerships for increasing investment in such ventures. A case study provides a successful example of how housing preservation and neighborhood revitalization can be accomplished through the use of a public-private partnership.
Global wellposedness to incompressible inhomogeneous fluid system with bounded density and non-Lipschitz velocity
Creators: name: Huang, Jingchi
name: Paicu, Marius
name: Zhang, Ping
Publisher: name: arXiv
Year: 2012
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this paper, we first prove the global existence of weak solutions to the d-dimensional incompressible inhomogeneous Navier-Stokes equations with initial data in critical Besov spaces, which satisfies a non-linear smallness condition. The regularity of the initial velocity is critical to the scaling of this system and is general enough to generate non-Lipschitz velocity field. Furthermore, with additional regularity assumption on the initial velocity or on the initial density, we can also prove the uniqueness of such solution. We should mention that the classical maximal regularity theorem for the heat kernel plays an essential role in this context.
Field Programmable DSP Arrays - A Novel Reconfigurable Architecture for Efficient Realization of Digital Signal Processing Functions
Creators: name: Sinha, Amitabha
name: Acharyya, Soumojit
name: Chakraborty, Suranjan
name: Sarkar, Mitrava
Publisher: name: arXiv
Year: 2013
Subjects: subject: Other Computer Science (cs.OH)
subject: FOS: Computer and information sciences

description: Digital Signal Processing functions are widely used in real time high speed applications. Those functions are generally implemented either on ASICs with inflexibility, or on FPGAs with bottlenecks of relatively smaller utilization factor or lower speed compared to ASIC. The proposed reconfigurable DSP processor is redolent to FPGA, but with basic fixed Common Modules (CMs) (like adders, subtractors, multipliers, scaling units, shifters) instead of CLBs. This paper introduces the development of a reconfigurable DSP processor that integrates different filter and transform functions. The switching between DSP functions is occurred by reconfiguring the interconnection between CMs. Validation of the proposed reconfigurable architecture has been achieved on Virtex5 FPGA. The architecture provides sufficient amount of flexibility, parallelism and scalability.
description: 18 pages, 17 figures. This paper has been published into Signal & Image Processing : An International Journal (SIPIJ - AIRCC) Vol.4, No.2, April 2013. http://airccse.org/journal/sipij/current2013.html
Juniperus communis L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: P. communis L. Cat. 141. I._ D._Die Wildform:var. Achras (Gärtner) Wallr. bis1525m (ob Fully,nach Garns);die var.Pyraster ¬¬¬ L.und var. sativa DC. kultiviert und verwildert.
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Analytical Light Curve Models of Super-Luminous Supernovae: chi^2-Minimizations of Parameter Fits
Creators: name: Chatzopoulos, E.
name: Wheeler, J. C.
name: Vinko, J.
name: Horvath, Z. L.
name: Nagy, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present fits of generalized semi-analytic supernova (SN) light curve (LC) models for a variety of power inputs including Ni-56 and Co-56 radioactive decay, magnetar spin-down, and forward and reverse shock heating due to supernova ejecta-circumstellar matter (CSM) interaction. We apply our models to the observed LCs of the H-rich Super Luminous Supernovae (SLSN-II) SN 2006gy, SN 2006tf, SN 2008am, SN 2008es, CSS100217, the H-poor SLSN-I SN 2005ap, SCP06F6, SN 2007bi, SN 2010gx and SN 2010kd as well as to the interacting SN 2008iy and PTF09uj. Our goal is to determine the dominant mechanism that powers the LCs of these extraordinary events and the physical conditions involved in each case. We also present a comparison of our semi-analytical results with recent results from numerical radiation hydrodynamics calculations in the particular case of SN 2006gy in order to explore the strengths and weaknesses of our models. We find that CS shock heating produced by ejecta-CSM interaction provides a better fit to the LCs of most of the events we examine. We discuss the possibility that collision of supernova ejecta with hydrogen-deficient CSM accounts for some of the hydrogen-deficient SLSNe (SLSN-I) and may be a plausible explanation for the explosion mechanism of SN 2007bi, the pair-instability supernova (PISN) candidate. We characterize and discuss issues of parameter degeneracy.
description: 52 pages, 9 figures
title: Marion Lichardus-Itten: Die Gräberfelder der Großgartacher Gruppe im Elsaß. Bonn 1980
Creators: name: Mansfeld, Günter
Publisher: name: University Library Heidelberg
Year: 2016

description: Rezension zu: Marion Lichardus-Itten: Die Gräberfelder der Großgartacher Gruppe im Elsaß. Saarbrükker Beiträge zur Altertumskunde Band 25. Rudolf Habelt Verlag, Bonn 1980. 217 Seiten, 1 Karte, 10 Pläne, 33 Tafeln.
Comprehensive molecular characterization of human colon and rectal cancer
Creators: name: Perou, Charles
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale analysis of 276 samples, analysing exome sequence, DNA copy number, promoter methylation and messenger RNA and microRNA expression. A subset of these samples (97) underwent low-depth-of-coverage whole-genome sequencing. In total, 16% of colorectal carcinomas were found to be hypermutated: three-quarters of these had the expected high microsatellite instability, usually with hypermethylation and MLH1 silencing, and one-quarter had somatic mismatch-repair gene and polymerase ε (POLE) mutations. Excluding the hypermutated cancers, colon and rectum cancers were found to have considerably similar patterns of genomic alteration. Twenty-four genes were significantly mutated, and in addition to the expected APC, TP53, SMAD4, PIK3CA and KRAS mutations, we found frequent mutations in ARID1A, SOX9 and FAM123B. Recurrent copy-number alterations include potentially drug-targetable amplifications of ERBB2 and newly discovered amplification of IGF2. Recurrent chromosomal translocations include the fusion of NAV2 and WNT pathway member TCF7L1. Integrative analyses suggest new markers for aggressive colorectal carcinoma and an important role for MYC-directed transcriptional activation and repression.
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus
Creators: name: Loesch, Kim
name: Sun, Jiaren
name: Yang, Yan
name: Lemon, Stanley M.
name: Xiao, Shu-Yuan
name: Beard, Michael R.
name: Lerat, Hervé
name: Okuda, Michiari
name: Honda, Masao
name: Gosert, Rainer
name: Weinman, Steven A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Background and Aims: The aim of this study was to determine whether expression of hepatitis C virus proteins alters hepatic morphology or function in the absence of inflammation. Methods: Transgenic C57BL/6 mice with liver-specific expression of RNA encoding the complete viral polyprotein (FL-N transgene) or viral structural proteins (S-N transgene) were compared with nontransgenic littermates for altered liver morphology and function. Results: FL-N transcripts were detectable only by reverse-transcription polymerase chain reaction, and S-N transcripts were identified in Northern blots. The abundance of viral proteins was sufficient for detection only in S-N transgenic animals. There was no inflammation in transgenic livers, but mice expressing either transgene developed age-related hepatic steatosis that was more severe in males. Apoptotic or proliferating hepatocytes were not significantly increased. Hepatocellular adenoma or carcinoma developed in older male animals expressing either transgene, but their incidence reached statistical significance only in FL-N animals. Neither was ever observed in age-matched nontransgenic mice. Conclusions: Constitutive expression of viral proteins leads to common pathologic features of hepatitis C in the absence of specific anti-viral immune responses. Expression of the structural proteins enhances a low background of steatosis in C57BL/6 mice, while additional low level expression of nonstructural proteins increases the risk of cancer.
Dimensional regularization of local singularities in the 4th post-Newtonian two-point-mass Hamiltonian
Creators: name: Jaranowski, Piotr
name: Schäfer, Gerhard
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The article delivers the only still unknown coefficient in the 4th post-Newtonian energy expression for binary point masses on circular orbits as function of orbital angular frequency. Apart from a single coefficient, which is known solely numerically, all the coefficients are given as exact numbers. The shown Hamiltonian is presented in the center-of-mass frame and out of its 57 coefficients 51 are given fully explicitly. Those coefficients are six coefficients more than previously achieved [Jaranowski/Schäfer, Phys. Rev. D 86, 061503(R) (2012)]. The local divergences in the point-mass model are uniquely controlled by the method of dimensional regularization. As application, the last stable circular orbit is determined as function of the symmetric-mass-ratio parameter.
description: 6 pages, 2 figures
Multipoint Lax operator algebras. Almost-graded structure and central extensions
Creators: name: Schlichenmaier, Martin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Algebra (math.QA)
subject: Mathematical Physics (math-ph)
subject: Algebraic Geometry (math.AG)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 17B65, 17B67, 17B80, 14H55, 14H70, 30F30, 81R10, 81T40

description: Recently, Lax operator algebras appeared as a new class of higher genus current type algebras. Based on I.Krichever's theory of Lax operators on algebraic curves they were introduced by I. Krichever and O. Sheinman. These algebras are almost-graded Lie algebras of currents on Riemann surfaces with marked points (in-points, out-points, and Tyurin points). In a previous joint article of the author with Sheinman the local cocycles and associated almost-graded central extensions are classified in the case of one in-point and one out-point. It was shown that the almost-graded extension is essentially unique. In this article the general case of Lax operator algebras corresponding to several in- and out-points is considered. In a first step it is shown that they are almost-graded. The grading is given by the splitting of the marked points which are non-Tyurin points into in- and out-points. Next, classification results both for local and bounded cocycles are shown. The uniqueness theorem for almost-graded central extensions follows. For this generalization additional techniques are needed which are presented in this article.
description: 42 pages
Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes
Creators: name: Lee Kraus, W.
name: Simper, Melissa S
name: Nagari, Anusha
name: Barton, Michelle C
name: Shen, Jianjun
name: Franco, Hector L
name: Bedford, Mark T
name: Dent, Sharon Y R
name: Li, Wenqian
name: Li, Wei
name: Keyomarsi, Khandan
name: Shi, Jiejun
name: Allton, Kendra L
name: Xi, Yuanxin
name: Tanaka, Kaori
name: Shi, Xiaobing
name: Coletta, Luis D
name: Malladi, Venkat S
name: Li, Jing
name: Richardson, Dana
Publisher: name: BioMed Central
Year: 2018

description: Abstract Background Epigenetic regulators are frequently mutated or aberrantly expressed in a variety of cancers, leading to altered transcription states that result in changes in cell identity, behavior, and response to therapy. Results To define alterations in epigenetic landscapes in breast cancers, we profiled the distributions of 8 key histone modifications by ChIP-Seq, as well as primary (GRO-seq) and steady state (RNA-Seq) transcriptomes, across 13 distinct cell lines that represent 5 molecular subtypes of breast cancer and immortalized human mammary epithelial cells. Discussion Using combinatorial patterns of distinct histone modification signals, we defined subtype-specific chromatin signatures to nominate potential biomarkers. This approach identified AFAP1-AS1 as a triple negative breast cancer-specific gene associated with cell proliferation and epithelial-mesenchymal-transition. In addition, our chromatin mapping data in basal TNBC cell lines are consistent with gene expression patterns in TCGA that indicate decreased activity of the androgen receptor pathway but increased activity of the vitamin D biosynthesis pathway. Conclusions Together, these datasets provide a comprehensive resource for histone modification profiles that define epigenetic landscapes and reveal key chromatin signatures in breast cancer cell line subtypes with potential to identify novel and actionable targets for treatment.
A Planning Career in the Triangle: Interview with Roger Waldon, FAICP
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Roger Waldon is a Principal Consultant with Clarion Associates in Chapel Hill, NC. He was also the planning director for the Town of Chapel Hill for 20 years and a graduate of the Department of City and Regional Planning at University of North Carolina at Chapel Hill. Carolina Planning conducted an interview on April 26, 2006 to talk with Waldon about his career and how planning in North Carolina has changed since he started practicing.
Rondino : pro housle (či hoboj, či klarinet) s průvodem orkestru = für Violine (oder Oboe, oder Clarinette) mit Orchesterbegleitung : klavírní výtah = Klavierauszug
Rondinos G-Dur arrangiert
Creators: name: Novotný, Václav Juda
Publisher: name: Fr. A. Urbánek, Verleger
Year: 1896

description: von / složil V.J. Novotný
Asymmetrische Fragmentsynthesen des Bryostatins (C1-C16 und C19-C27), Pederins (C10-C17), Leucascandrolids (C1-C9), Hennoxazols (C2-C8) und Macrolactins (C11-C17) : neuartige Entschützungsmethoden von SEM-Ethern und Dithianen
Creators: name: Vakalopoulos, Alexandros
Publisher: name: Hannover : Universität Hannover
Year: 2000
Subjects: subject: Bryostatins
subject: synthesis of natural products and analogues
subject: deprotection methods
subject: Asymmetrische Synthese
subject: Bryostatine
subject: Naturstoff
subject: Partialstruktur
subject: Schutzgruppe
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: [no abstract]
Serendipitous Discovery of Three Millisecond Pulsars with the GMRT in Fermi-directed Survey and Follow-up Radio Timing
Creators: name: Bhattacharyya, B.
name: Roy, J.
name: Freire, P.C.C.
name: Ray, P.S.
name: Johnson, T.J.
name: Gupta, Y.
name: Bhattacharya, D.
name: Kaninghat, A.
name: Ferrara, E.C.
name: Michelson, P.F.
Publisher: name: London : Institute of Physics Publ.
Year: 2022
Subjects: subject: Large-Area Telescope
subject: Binary
subject: Evolution
subject: Rotation
subject: Spectra
subject: Dewey Decimal Classification::500 | Naturwissenschaften::520 | Astronomie, Kartographie

description: We report the discovery of three millisecond pulsars (MSPs): PSRs J1120-3618, J1646-2142, and J1828+0625 with the Giant Metrewave Radio Telescope (GMRT) at a frequency of 322 MHz using a 32 MHz observing bandwidth. These sources were discovered serendipitously while conducting the deep observations to search for millisecond radio pulsations in the directions of unidentified Fermi Large Area Telescope (LAT) γ-ray sources. We also present phase coherent timing models for these MSPs using ∼5 yr of observations with the GMRT. PSR J1120-3618 has a 5.5 ms spin period and is in a binary system with an orbital period of 5.6 days and minimum companion mass of 0.18 M, PSR J1646-2142 is an isolated object with a spin period of 5.8 ms, and PSR J1828+0625 has a spin period of 3.6 ms and is in a binary system with an orbital period of 77.9 days and minimum companion mass of 0.27 M. The two binaries have very low orbital eccentricities, in agreement with expectations for MSP-helium white dwarf systems. Using the GMRT 607 MHz receivers having a 32 MHz bandwidth, we have also detected PSR J1646-2142 and PSR J1828+0625, but not PSR J1120-3618. PSR J1646-2142 has a wide profile, with significant evolution between 322 and 607 MHz, whereas PSR J1120-3618 exhibits a single peaked profile at 322 MHz and PSR J1828+0625 exhibits a single peaked profile at both the observing frequencies. These MSPs do not have γ-ray counterparts, indicating that these are not associated with the target Fermi LAT pointing emphasizing the significance of deep blind searches for MSPs. © 2022. The Author(s). Published by the American Astronomical Society.
Sculpting the disk around T Cha: an interferometric view
Creators: name: Olofsson, Johan
name: Benisty, Myriam
name: Bouquin, Jean-Baptiste Le
name: Berger, Jean-Philippe
name: Lacour, Sylvestre
name: Ménard, François
name: Henning, Thomas
name: Crida, Aurélien
name: Burtscher, Leonard
name: Meeus, Gwendolyn
name: Ratzka, Thorsten
name: Pinte, Christophe
name: Augereau, Jean-Charles
name: Malbet, Fabien
name: Lazareff, Bernard
name: Traub, Wesley A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: (Abridged) Circumstellar disks are believed to be the birthplace of planets and are expected to dissipate on a timescale of a few Myr. The processes responsible for the removal of the dust and gas will strongly modify the radial distribution of the dust and consequently the SED. In particular, a young planet will open a gap, resulting in an inner disk dominating the near-IR emission and an outer disk emitting mostly in the far-IR. We analyze a full set of data (including VLTI/Pionier, VLTI/Midi, and VLT/NaCo/Sam) to constrain the structure of the transition disk around TCha. We used the Mcfost radiative transfer code to simultaneously model the SED and the interferometric observations. We find that the dust responsible for the emission in excess in the near-IR must have a narrow temperature distribution with a maximum close to the silicate sublimation temperature. This translates into a narrow inner dusty disk (0.07-0.11 AU). We find that the outer disk starts at about 12 AU and is partially resolved by the Pionier, Sam, and Midi instruments. We show that the Sam closure phases, interpreted as the signature of a candidate companion, may actually trace the asymmetry generated by forward scattering by dust grains in the upper layers of the outer disk. These observations help constrain the inclination and position angle of the outer disk. The presence of matter inside the gap is difficult to assess with present-day observations. Our model suggests the outer disk contaminates the interferometric signature of any potential companion that could be responsible for the gap opening, and such a companion still has to be unambiguously detected. We stress the difficulty to observe point sources in bright massive disks, and the consequent need to account for disk asymmetries (e.g. anisotropic scattering) in model-dependent search for companions.
description: Removed the word "first" in the abstract of the paper: "obtained with the first 4-telescope combiner (VLTI/Pionier)"
Plasticity changes in forebrain activity and functional connectivity during neuropathic pain development in rats with sciatic spared nerve injury
Creators: name: Chao, Tzu-Hao H
name: Chen, Jyh-Horng
name: Yen, Chen-Tung
Publisher: name: BioMed Central
Year: 2018

description: Abstract
              Neuropathic pain is a major worldwide health problem. Although central sensitization has been reported in well-established neuropathic conditions, information on the acute brain activation patterns in response to peripheral nerve injury is lacking. This study first mapped the brain activity in rats immediately following spared nerve injury (SNI) of the sciatic nerve. Using blood-oxygenation-level-dependent functional magnetic resonance imaging (BOLD-fMRI), we observed sustained activation in the bilateral insular cortices (ICs), primary somatosensory cortex (S1), and cingulate cortex. Second, this study sought to link this sustained activation pattern with brain sensitization. Using manganese-enhanced magnetic resonance imaging (MEMRI), we observed enhanced activity in the ipsilateral anterior IC (AIC) in free-moving SNI rats on Days 1 and 8 post-SNI. Furthermore, enhanced functional connectivity between the ipsilateral AIC, bilateral rostral AIC, and S1 was observed on Day 8 post-SNI. Chronic electrophysiological recording experiments were conducted to confirm the tonic neuronal activation in selected brain regions. Our data provide evidence of tonic activation-dependent brain sensitization during neuropathic pain development and offer evidence that the plasticity changes in the IC and S1 may contribute to neuropathic pain development.
Social Network for Smart Devices using Embedded Ethernet
Creators: name: Sheth, Ketul
name: Shah, Shreya
name: Shah, Darshan
name: Odhekar, Anuja
Publisher: name: arXiv
Year: 2013
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: Embedded Ethernet is nothing but a microcontroller which is able to communicate with the network. A design of AVR controller-based embedded Ethernet interface is presented. In the design, an existing SPI serial device can be converted into a network interface peripheral to obtain compatibility with the network. By typing the IP-address of LAN on the web browser, the user gets a web page on screen; this page contains all the information about the status of the devices. The user can also control the devices interfaced to the web server by pressing buttons provided in the web page. This creates a network for easy communication among the devices.
description: 15 pages, 8 figures, Submitted to: 'Computer Science and Engineering: An International Journal', Currently we are working on further enhancing the website to give the appearance of a social networking website
Aria
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. Aria (L.) Crantz Cat. 141. Verbreitet; im Mattertal aufwärts nicht nur bis St. Niklaus (Cat.) bzw. Herbriggen (Beauverd), sondern bis Zermatt (Thellung). Bis 2155 m: Portail de Fully (Garns). Var. carpinifolia Petzold et Kirchner - 2: Ayent (P.). Var. longifolia Pers. (var. edulis [Willd.] Wenzig) - l: Evionnaz (F.). - Angenähert auch bei Gondo (Becherer). Var. salicifolia Myrin - l: Le Chätelard (Wilczek und Coquoz). Die ssp. tomentosa Rouy et Camus, von G. BEAUVERD von Visperterminen und - angenähert - von Visp-Stalden angegeben, ist zu streichen.
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
A survey on energy efficiency for wireless mesh network
Creators: name: Mamechaoui, Sarra
name: Didi, Fedoua
name: Pujolle, Guy
Publisher: name: arXiv
Year: 2013
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Reducing CO2 emissions is an important global environmental issue. Over the recent years, wireless and mobile communications have increasingly become popular with consumers. An increasingly popular type of wireless access is the so-called Wireless Mesh Networks (WMNs) that provide wireless connectivity through much cheaper and more flexible backhaul infrastructure compared with wired solutions. Wireless Mesh Network (WMN) is an emerging new technology which is being adopted as the wireless internetworking solution for the near future. Due to increased energy consumption in the information and communication technology (ICT) industries, and its consequent environmental effects, energy efficiency has become a key factor to evaluate the performance of a communication network. This paper mainly focuses on classification layer of the largest existing approaches dedicated to energy conservation. It is also discussing the most interesting works on energy saving in WMNs networks.
description: International Journal of Computer Networks & Communications (IJCNC) Vol.5, No.2, March 2013
On the potential role of the Collins effect in A_N in pp --> pion X
Creators: name: Anselmino, M.
name: Boglione, M.
name: D'Alesio, U.
name: Leader, E.
name: Melis, S.
name: Murgia, F.
name: Prokudin, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Transverse single spin asymmetries in pp --> pion X processes, while on a quite firm ground experimentally, are still a much debated phenomenological issue. We consider them in a transverse momentum dependent factorization scheme. After revisiting a previous result, we give new estimates of the Collins contribution by adopting the latest information on the Collins and transversity functions, as extracted from SIDIS and e+e- data.
description: 4 pages, 4 figures, uses cimento.cls. Talk delivered by U. D'Alesio at the "3rd Workshop on the QCD Structure of the Nucleon" (QCD-N'12), Oct. 22-26, 2012, Bilbao, Spain. Submitted to "Il Nuovo Cimento C"
Human Services Planning: Familiar Problems, New Solutions
Creators: name: Guffey, David
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: In a recent article in the National Journal , Rochelle L. Stanfield, staff correspondent, wrote: To most thoughtful critics of the New Federalism the President's proposal is neither the perfect solution nor the wrong one, but is a starting place for a comprehensive reconsideration of intergovernmental relationships. Some may be led to believe that human services are facing the current situation only as a result of the most recent budget consolidations and reductions. However, the debate on the roles for federal, state and local governments and the voluntary sector in providing human services is not new. It was an important concern during the formation of the Republic, in the Roosevelt Administration, during the Nixon Administration, and now under President Reagan. Human services at the local level are facing a longer term problem than just the actions of the current administration. It is problem that consists at least of: continued reductions in some programs, no real growth in funds for others, inadequate staffing, and community criticism over the effectiveness of local services. These realities will be with us regardless of the national administration.
Core-shell multi-quantum wells in ZnO / ZnMgO nanowires with high optical efficiency at room temperature
Creators: name: Thierry, Robin
name: Perillat-Merceroz, Guillaume
name: Jouneau, Pierre-Henri
name: Ferret, Pierre
name: Feuillet, Guy
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Nanowire-based light-emitting devices require multi-quantum well heterostructures with high room temperature optical efficiencies. We demonstrate that such efficiencies can be attained through the use of ZnO/Zn(1-x)MgxO core shell quantum well heterostructures grown by metal organic vapour phase epitaxy. Varying the barrier Mg concentration from x=0.15 to x=0.3 leads to the formation of misfit induced dislocations in the multi quantum wells. Correlatively, temperature dependant photoluminescence reveals that the radial well luminescence intensity decreases much less rapidly with increasing temperature for the lower Mg concentration. Indeed, about 54% of the 10K intensity is retained at room temperature with x=0.15, against 2% with x=0.30. Those results open the way to the realization of high optical efficiency nanowire-based light emitting diodes.
Urban Greening in North Carolina: Case Studies from New Bern, Mecklenburg County, and Raleigh
Creators: name: Wilhelm, Will
name: Cragnolin, Karen
name: Gordon, Jimmy
name: Brantley, James
name: Thomas, Susan Moffat
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Carolina Planning regularly solicits articles on recent projects from members of the North Carolina chapter of the American Planning Association (NCAPA). This year’s submissions focused on water resource management – an important element of urban greening efforts. From a riverwalk in New Bern – the host city for the 2010 NCAPA Conference – to a stream restoration project in Mecklenburg County and an educational wetlands park in Raleigh, these projects provide valuable insight into the local planning process.
Formation of Regular Satellites from Ancient Massive Rings in the Solar System
Creators: name: Crida, A.
name: Charnoz, S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: When a planetary tidal disk -like Saturn's rings- spreads beyond the Roche radius (inside which planetary tides prevent aggregation), satellites form and migrate away. Here, we show that most regular satellites in the solar system probably formed in this way. According to our analytical model, when the spreading is slow, a retinue of satellites appear with masses increasing with distance to the Roche radius, in excellent agreement with Saturn's, Uranus', and Neptune's satellite systems. This suggests that Uranus and Neptune used to have massive rings that disappeared to give birth to most of their regular satellites. When the spreading is fast, only one large satellite forms, as was the case for Pluto and Earth. This conceptually bridges the gap between terrestrial and giant planet systems.
description: published in Science on Nov 30, 2012. 16 pages, 5 figures (Main text: 5 pages. Supplementary Material: 10 pages. References: 1 page)
Interroom radiative couplings through windows and large openings in buildings: Proposal of a simplified model
Creators: name: Boyer, H.
name: Bojic, M.
name: Ennamiri, H.
name: Calogine, D.
name: Guichard, S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Computer and information sciences

description: A simplified model of indoor short wave radiation couplings adapted to multi-zone simulations is proposed, thanks to a simplifying hypothesis and to the introduction of an indoor short wave exchange matrix. The specific properties of this matrix appear useful to quantify the thermal radiation exchanges between the zones separated by windows or large openings. Integrated in CODYRUN software, this module is detailed and compared to experimental measurements carried out on a real scale tropical building.
Ignoring regression to the mean leads to unsupported conclusion about obesity
Creators: name: Skinner, Asheley
name: Faith, Myles S
name: Allison, David B
name: Pietrobelli, Angelo
name: Heymsfield, Steven B
Publisher: name: BioMed Central
Year: 2015

description: Abstract Childhood obesity remains a substantial health concern for our population and thoughtful attempts to develop and evaluate the utility of programs to reduce childhood obesity levels are needed. Unfortunately, we believe the conclusion by Burke et al. that the HealthMPowers program produces positive change in body composition is incorrect because the results obtained are likely due to regression to the mean (RTM), a well-known threat to the validity of studies that is often overlooked. Using empirical data, we demonstrate that RTM is likely to be the cause for the changes reported. A more reasonable conclusion than the one of effectiveness the authors offered would be that the results did not support the effectiveness of the intervention. Public health officials, parents, school leaders, community leaders, and regulators need and deserve valid evidence free from spin on which they can base decisions.
Inverse, protean, and ligand-selective agonism: Matters of receptor conformation
Creators: name: Kenakin, Terry
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Concepts regarding the mechanisms by which drugs activate receptors to produce physiological response have progressed beyond considering the receptor as a simple on-off switch. Current evidence suggests that the idea that agonists produce only varying degrees of receptor activation is obsolete and must be reconciled with data to show that agonist efficacy has texture as well as magnitude. Thus, agonists can block system constitutive response (inverse agonists), behave as positive and inverse agonists on the same receptor (protean agonists), and differ in the stimulus pattern they produce in physiological systems (ligand-selective agonists). The molecular mechanism for this seemingly diverse array of activities is the same, namely, the selective microaffinity of ligands for different conformational states of the receptor. This paper reviews evidence for the existence of the various types of agonism and the potential therapeutic utility of different agonist types.
Sorbus mougeotii Soyer et Godron
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. Mougeotii Soyer et Godron (S. scandica Gren. et Godron, non Fries) Cat. 141. l: Les Gietes ob St-Maurice (J.); ob Evionnaz (F.); Umgebung von Salvan (Coquoz); IVIont- Ravoire (F.) - 2: Mayensde Fully (Garns); ob Ayent (P.); Heidnischbielbei Raron (Lüdi). - 3: Les Assets ob Le Borgeau (F.); Liddes (P.); Bourg-St-Pierre (Guyot); Valsorey (idem); Visperterminen (Beauverd). - 4: Binntal (Binz, P.); ob Ernen (nach Wilczek); Fiesch-Fürgangen (desgl.).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Ferromagnetic quantum critical point in UCo1-xFexGe
Creators: name: Huang, K.
name: Hamlin, J. J.
name: Baumbach, R. E.
name: Janoschek, M.
name: Kanchanavatee, N.
name: Zocco, D. A.
name: Ronning, F.
name: Maple, M. B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We have carried out a comprehensive study of the UCo1-xFexGe series across the entire range of compositions 0 <= x <= 1, and report the results of x-ray diffraction, magnetization, specific heat, and electrical resistivity to uncover the T-x phase diagram. Substitution of Fe into UCoGe initially results in an increase in the Curie temperature and a rapid destruction of the superconductivity. Near x = 0.22, the ferromagnetic transition is suppressed to zero temperature at an apparent ferromagnetic itinerant electron quantum critical point, where the temperature dependence of the electrical resistivity and specific heat in this region reveal non-Fermi liquid behavior.
description: 7 pages, 7 figures
Optomechanical resonator-enhanced atom interferometry
Creators: name: Richardson, Logan L.
name: Rajagopalan, Ashwin
name: Albers, Henning
name: Meiners, Christian
name: Nath, Dipankar
name: Schubert, Cchristian
name: Tell, Dorothee
name: Wodey, Étienne
name: Abend, Sven
name: Gersemann, Mathias
name: Ertmer, Wolfgang
name: Rasel, Ernst M.
name: Schlippert, Dennis
name: Mehmet, Moritz
name: Kumanchik, Lee
name: Colmenero, Luis
name: Spannagel, Ruven
name: Braxmaier, Claus
name: Guzmán, Felipe
Publisher: name: Berlin [u.a.] : Nature Research
Year: 2020
Subjects: subject: atoms
subject: interferometry
subject: resonators
subject: atom interferometry
subject: dynamic range
subject: matter waves
subject: noisy environment
subject: optomechanical
subject: quantum engineering
subject: quantum sensors
subject: stable measurements
subject: optomechanics
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: Matter-wave interferometry and spectroscopy of optomechanical resonators offer complementary advantages. Interferometry with cold atoms is employed for accurate and long-term stable measurements, yet it is challenged by its dynamic range and cyclic acquisition. Spectroscopy of optomechanical resonators features continuous signals with large dynamic range, however it is generally subject to drifts. In this work, we combine the advantages of both devices. Measuring the motion of a mirror and matter waves interferometrically with respect to a joint reference allows us to operate an atomic gravimeter in a seismically noisy environment otherwise inhibiting readout of its phase. Our method is applicable to a variety of quantum sensors and shows large potential for improvements of both elements by quantum engineering. © 2020, The Author(s).
Evaluation of polyplexes as gene transfer agents
Creators: name: Gebhart, Catherine L.
name: Kabanov, Alexander V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Non-viral transfection systems based on the complexes of DNA and polycations (‘polyplexes’) were evaluated with respect to their effectiveness, toxicity and cell type dependence in a variety of in vitro models. The panel of polycations examined included branched and linear polyethyleneimines, poly[N-ethyl-4-vinyl pyridinium bromide], polyamidoamine dendrimer (Superfect™), poly(propyleneimine) dendrimer (Astramol™) and a conjugate of Pluronic® P123 and polyethyleneimine (P123-g-PEI(2K)), having a graft-block copolymer architecture. Using a panel of cell lines the linear polyethyleneimine ExGen™ 500, Superfect™, branched polyethyleneimine 25 kDa, and P123-g-PEI(2K) were determined as systems displaying highest transfection activity while exhibiting relatively low cytotoxicity. These systems had activity higher than or comparable to lipid transfection reagents (Lipofectin®, LipofectAMINE™, CeLLFECTIN® and DMRIE-C) but did not reveal serum dependence and were less toxic than the lipids. Overall, this study demonstrates good potential of structurally diverse polyplex systems as transfection reagents with relatively low cytotoxicity.
Modulation of skyrmionic magnetic textures in two-dimensional vdW materials and their heterostructures
Creators: name: Yao, Xiaoyan
name: Hu, Di
name: Dong, Shuai
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The intrinsic magnetism observed in two-dimensional (2D) van der Waals (vdW) materials provides a unique opportunity for exploring the 2D topological magnetic textures, in particular skyrmionic magnetic textures (SMTs) including skyrmion and its topological equivalents. Since the experimental discovery of skyrmions in the 2D vdW materials and their heterostructures, a critical challenge lies in the control of these SMTs to translate their intriguing features into spintronic applications. Here, we review the recent experimental and theoretical progresses on the modulations of SMTs in 2D vdW monolayer materials and their heterostructures. Besides well-established basic modulation factors including temperature, magnetic field and sample thickness, we present the experimental realization of mobility and transition driven by electric current, and the theoretical prediction of diverse magnetoelectric modulations by electric field. Considering the 2D character of vdW layered materials, strain and stacking style are also efficient approaches to tune the magnetic textures.
description: 19 pages, 6 figures; a review
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins
Creators: name: Hollenberg, Paul F.
name: Edwards, David J.
name: He, Kan
name: Fitzsimmons, Michael E.
name: Fisher, Jeannine M.
name: Rahman, Atiqur
name: Thummel, Kenneth E.
name: Lown, Kenneth S.
name: Woster, Patrick M.
name: Schmiedlin-Ren, Phyllissa
name: Watkins, Paul B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1997

description: Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit juice ingestion results in a loss of CYP3A4 from the small bowel epithelium. We now show that the reduction in intestinal CYP3A4 concentration is rapid; a 47% decrease occurred in a healthy volunteer within 4 hr after consuming grapefruit juice. To identify the specific components of the juice responsible for this effect, we used a recently developed Caco-2 cell culture model of human intestinal epithelium that expresses catalytically active CYP3A4. We found that grapefruit oil and two furanocoumarin constituents (6*,7*-dihydroxybergamottin and a closely related dimer) caused a dose-dependent fall in CYP3A4 catalytic activity and immunoreactive CYP3A4 concentration. The effect was selective in that concentrations of CYP1A1 and CYP2D6 did not fall, consistent with previous results obtained in vivo. Assays of various juices confirmed that 6*,7*-dihydroxybergamottin is the major furanocoumarin present and, although its concentration varies significantly among types and brands of grapefruit juice, it is consistently present in concentrations exceeding the IC50 (1 mM) for loss of midazolam 1*-hydroxylase activity determined in the Caco-2 cells. Studies with recombinant CYP3A4 revealed that 6*,7*-dihydroxybergamottin is a mechanism-based inactivator, which supports the idea that loss of CYP3A4 results from accelerated degradation of the enzyme. We conclude that the effect of grapefruit juice on oral availability of CYP3A4 substrates can be largely accounted for by the presence of 6*,7*-dihydroxybergamottin although other furanocoumarins probably also contribute.
Innovative Aufreinigungsstrategien auf Membranadsorberbasis für rekombinante Zytokine
Creators: name: Gieseler, Gesa-Maria
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2019
Subjects: subject: Membranchromatographie
subject: axiale Membranadsorber
subject: tangentiale Membranadsorber
subject: FGF-2 rekombinante Proteinproduktion
subject: rhBMP-2
subject: rhBMP-4
subject: rekombinante Zytokine
subject: Inclusion Bodies
subject: mixed mode Membranchromatographie
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: Downstream processing accounts for substantial cost in the production of cytokines. To overcome the limitations of commonly used packed bed chromatography columns, innovative cation exchange membrane adsorbers as a basis for rapid bioseparation are presented. Here, the transport of solutes to the binding sites takes place predominantly by convection, thereby reducing both process time and eluate volume. Moreover, scale up of membrane chromatography is simple due to its modular format. While membrane chromatography in direct capture mode integrates clarification and protein capture into one single unit operation and thus reduces the number of stages in the downstream process. Additionally, we introduce new weak and strong cation exchange membrane adsorbers combining mixed mode ligand chemistry and an optimized membrane platform for the purification of cytokines. The results show that the ligand chemistry as well as the membrane matrix can have impact on the selectivity, binding and the recovery of the cytokine.The membrane-based bioseparation technology made large scale purification of high-value proteins possible. Implementation of a functional upscaling process was required for economic feasibility. We introduce three model proteins to apply alternative purification strategies using membrane chromatography. Due to their unique structural motive, purification is rather challenging. High protein aggregation and renaturation steps accounts for complexity of the isolation process. Another aspect is the implementation of an animal component free process. Here, membrane adsorber strategies substitute conventional approaches using heparin chromatography. This plays in important role for the certification of the product regarding purity.
Quantum quench dynamics of the Coulomb Luttinger model
Creators: name: Nessi, N.
name: Iucci, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the non-equilibrium dynamics of the Luttinger model after suddenly turning on and off the bare Coulomb interaction between the fermions. We analyze several correlation functions such as the one particle density matrix and vertex correlations, its finite time dynamics and the stationary state limit. Correlations exhibit a non-linear light cone effect: the spreading of the initial signal accelerates as a consequence of the quantum nature of the excitations, whose peculiar dispersion of plasmonic type in 1D gives rise to a logarithmic divergence in the group velocity at $q=0$. In addition we show that both the static and dynamic stationary state correlations can be reproduced with a simple generalised Gibbs ensemble despite the long-range character of the interactions which precludes the application of the Lieb-Robinson bounds. We propose a suitable experimental setup in which these effect can be observed based on ultracold ions loaded on linear traps.
description: 13 pages, 7 figures
The effect of trailing edge geometry on cavity flow oscillation driven by a supersonic shear layer
Creators: name: Rona, Aldo
name: Zhang, Xin
name: Edwards, John Andrew.
Publisher: name: figshare
Year: 2022
Subjects: subject: 90101 Aerodynamics (excl. Hypersonic Aerodynamics)
subject: FOS: Mechanical engineering
subject: Aerospace Engineering
subject: 91501 Computational Fluid Dynamics
subject: FOS: Other engineering and technologies

description: A computational analysis is per rmed of self-sustained oscillatory flow over a cavity driven by a shear layer at Mach 1-5. The unsteady flow is studied through solutions of the Reynolds-averaged Navier-­Stokes equations with turbulence modelled by a two-equation k-omega model. The trailing edge (face) of a baseline rectangular cavity is modified using wedge and ramp shapes to investigate means for the suppression and attenuation of the self-sustained oscillation. Through modification of the shear layer impingement, both wedge and ramp are effective in reducing the level of oscillation. The time­ averaged pressure (form) drag coefficient of the cavity is also reduced significantly. The main cause of the drag reduction is the elimination or reduction of the high pressure area near the down­stream corner of the cavity due to the presence of a vortex. Two types of unsteady flow exist when a curved ramp is employed: 'regular' and 'random'. The use of a h = 0.6D ramp generates a random type pressure fluctuation with lower rms pressure compared with the h = 0.2D and 0.4D ramps.
 AERONAUTICAL JOURNAL 102(1013):129-136 01 Mar 1998