cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of a novel point mutation in ENT1 that confers resistance to Ara-C in human T cell leukemia CCRF-CEM cells
Creators: name: Huang, Min
name: Wang, Yanhong
name: Yang, Jing
name: Leisewitz, Andrea V.
name: Graves, Lee M.
name: Zimmerman, Eric I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: The genetic basis for the Ara-C resistance of CCRF-CEM Ara-C/8C leukemia cells was investigated. DNA sequencing revealed that these cells expressed an equilibrative nucleoside transporter 1 (ENT1) with a single missense mutation resulting in glycine to arginine replacement (G24R). To test the importance of this residue, additional G24 mutants were created and examined for [3H]-uridine and [3H]-Ara-C uptake. Both a G24E and G24A mutant showed reduced ENT1-dependent activity. An EGFP-tagged G24R ENT1 displayed plasma membrane localization even though it was unable to bind [3H]-NBMPR, an ENT1-specific inhibitor. These results define G24 as critical amino acid for ENT1 nucleoside uptake and suggest that mutations in TM1 may provide a mechanism for Ara-C resistance in CCRF-CEM Ara-C/8C cells.
Market Analysis Brazil: BUS 18
Creators: name: Market Analysis
Publisher: name: Roper Center for Public Opinion Research
Year: 2023

description: Previous participation/experience with surveys (3); interest in future market research (3); feelings on market research (1); ownership of electronics/appliances (5); ever used a PC (1); accessing the internet (10); activities done online (2); internet usage frequency (1); chance of using the internet in the future (2); most important issue facing Brazil (1); personal safety/experience with crime (20); leisurely activities (1); gender relations (2); grocery shopping (1); environment (4); presidential election (1); political parties (3); President Lula performance rating (2); priorities of government (1); occupation of Iraq (1); influence of the United States (2); participation in social projects/charity (3).
Magic State Distillation and Gate Compilation in Quantum Algorithms for Quantum Chemistry
Creators: name: Trout, Colin J.
name: Brown, Kenneth R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum algorithms for quantum chemistry map the dynamics of electrons in a molecule to the dynamics of a coupled spin system. To reach chemical accuracy for interesting molecules, a large number of quantum gates must be applied which implies the need for quantum error correction and fault-tolerant quantum computation. Arbitrary fault-tolerant operations can be constructed from a small, universal set of fault-tolerant operations by gate compilation. Quantum chemistry algorithms are compiled by decomposing the dynamics of the coupled spin-system using a Trotter formula, synthesizing the decomposed dynamics using Clifford operations and single-qubit rotations, and finally approximating the single-qubit rotations by a sequence of fault-tolerant single-qubit gates. Certain fault-tolerant gates rely on the preparation of specific single-qubit states referred to as magic states. As a result, gate compilation and magic state distillation are critical for solving quantum chemistry problems on a quantum computer. We review recent progress that has improved the efficiency of gate compilation and magic state distillation by orders of magnitude.
description: 17 pages, 3 figures, 1 table in Int. J. Quantum Chem. 2014
Older adults who started exercising after a fall were less likely to experience another fall in the following two years
Creators: name: Choi, Namkee G.
name: Marti, C. Nathan
name: Choi, Bryan Y.
Publisher: name: University of Texas at Austin Population Research Center
Year: 2023
Subjects: recurrent fall risk
U.S. National Health and Aging Trend Study (NHATS)
fall risk

description: More than 25% of adults age 65 and over fall every year in the United States. Among older adults who fall, approximately 40% experience two or more falls in the same year. Falls often result from a combination of physical or functional, medical, psychological, sensory and cognitive risk factors and environmental circumstances. In recurrent falls – that is, two or more falls in a year or over a given timeframe – previous falls are the most significant additional risk factor. This brief, from CAPS Faculty Affiliate Namkee Choi and colleagues, summarizes findings from a recent study that used longitudinal data from a nationally representative sample of adults age 70 and older to examine single and recurrent fall risk and impacts over 3 years. They found that rates of falling were high among older adults; older adults who started exercising after a fall in 2019 were less likely to experience a recurrent fall in the following 2 years; both a single fall and recurrent falls were associated with a higher risk of hospitalization; older adults with recurrent falls had worse physical or functional health and more psychological health problems at baseline compared to older adults who did not fall; and racial and ethnic differences in the risk of single and recurrent falls were identified. To reduce falls among older adults, they advocate for expanding the reach of evidence-based fall prevention programs.
Touch induces ATP release in Arabidopsis roots that is modulated by the heterotrimeric G-protein complex
Creators: name: Garrett, Michele B.
name: Kim, Sung-Yong
name: Swanson, Sarah J.
name: Okada, Seiko F.
name: Weerasinghe, Ravisha R.
name: Gilroy, Simon
name: Jones, Alan M.
name: Boucher, Richard C.
name: Stacey, Gary
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Amongst the many stimuli orienting the growth of plant roots, of critical importance are the touch signals generated as roots explore the mechanically complex soil environment. However, the molecular mechanisms behind these sensory events remain poorly defined. We report an impaired obstacle-avoiding response of roots in Arabidopsis lacking a heterotrimeric G protein. Obstacle avoidance may utilize a touch-induced release of ATP to the extracellular space. While sequential touch stimulation revealed a strong refractory period for ATP release in response to mechanostimulation in wild-type plants, the refractory period in mutants was attenuated, resulting in extracellular ATP accumulation. We propose that ATP acts as an extracellular signal released by mechanostimulation and that the G-protein complex is needed for fine-tuning this response.
Control Design of Inverter-based Resources in Power Systems
Creators: name: RATHNAYAKE, DAYAN BANDARA
Publisher: name: Monash University
Year: 2023
Subjects: Electrical energy generation (incl. renewables, excl. photovoltaics)
Power electronics

description: This thesis investigates the designing and prototyping of renewable energy-based generators to provide capabilities and services that are conventionally provided by fossil-fuel driven power plants. It proposes new control methodologies for the strengthening assets in the power system to keep the lights on. The findings of this thesis may enable secure and reliable operation of the power system while incorporating more renewable energy into the power system.
Urban planning for the temperature extremes: an EO-based journey towards an operational ML model to map human exposure to temperature extremes
Creators: name: Oliveira, Ana
name: Soares, Amilcar
name: Lopes, Antonio
name: Fonteles, Caio
name: Coreria, Ezequiel
name: Buroni, Giovanni
name: Eugénio, Guilherme
name: Galamba, Manuel
name: Loureiro, Nuno
name: Unas, Pedro
name: Cunha, Rita
name: Niza, Samuel
name: Leal, Vasco
Publisher: name: Zenodo
Year: 2022

description: Climate coffee of 15 September 2022, with the support of Blue-Action and the European Climate Research Alliance. Other useful resources to the topic: Resources The operational model: http://coastsense.colabatlantic.com/ https://www.sciencedirect.com/science/article/pii/S0048969721027819 https://www.sciencedirect.com/science/article/pii/S2212094722000391 Ongoing projects also focusing/covering heatwaves like EXHAUSTION, CityCLIM, XAIDA: EXHAUSTION https://cordis.europa.eu/project/id/820655 CityCLIM https://cordis.europa.eu/project/id/101036814 XAIDA https://cordis.europa.eu/project/id/101003469 Data on air quality also from the EEA: They have an app developed recently too European city air quality viewer — European Environment Agency (europa.eu) Urban data for 100 EU cities at 100-m resolution available from https://cds.climate.copernicus.eu/cdsapp#!/dataset/sis-urban-climate-cities?tab=overview (provided by Koen De Ridder, VITO)
Wirkungslos: Frankreich betreibt auf gesetzlichem Wege Sprachreinigung
Creators: name: Nientiedt, Klaus
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 48 Nr. 8 (1994): Herder Korrespondenz, Band 48, Heft 8
Exact solutions of the Gerdjikov-Ivanov equation using Darboux transformations
Creators: name: Yilmaz, Halis
Publisher: name: arXiv
Year: 2015
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences
subject: 35C08, 35Q55, 37K10, 37K35

description: We study the Gerdjikov-Ivanov (GI) equation and present a standard Darboux transformation for it. The solution is given in terms of quasideterminants. Further, the parabolic, soliton and breather solutions of the GI equation are given as explicit examples.
description: 16 pages, 4 figures
First steps of the GOLEM ontology for narrative and fiction
Creators: name: Pianzola, Federico
name: Yang, Xiaoyan
Publisher: name: Zenodo
Year: 2023
Subjects: computational literary studies
digital humanities
formal ontology
data modeling
knowledge graph

description: The first event organised by the GOLEM team at the University of Groningen was a hybrid workshop on Ontologies for Narrative and Fiction (in cooperation with the Center for Language and Cognition, the Center for Digital Humanities, and the Jantina Tammes School of Digital Society, Technology and AI). This workshop brought together an amazing spectrum of expertise and experience with modelling themes, genres, narratives and characters in fiction using an array of approaches from BFO, CIDOC-CRM/FRBRoo/LRMoo, the Wikibase data model, Schema.org, custom bottom-up models and so on, as well as with exploring the potential interoperability of these models. All the presentation slides are now available on the workshop’s page.
Chloride channels of intracellular membranes
Creators: name: Kahl, Christina R.
name: Edwards, John C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a role in intracellular chloride transport for each of these proteins.
Polar meron-antimeron networks in strained and twisted bilayers
Creators: name: Slager, Robert-Jan
Publisher: name: Apollo - University of Cambridge Repository
Year: 2023
Subjects: Article
/639/301/119/2792/4128
/639/301/119/996
/639/301/357/1018
article

description: Acknowledgements: D.B. acknowledges funding from the University of Liége under special funds for research (IPD-STEMA fellowship program) and St. John’s College, University of Cambridge. R.-J.S. and G.C. acknowledge funding from a New Investigator Award, EPSRC grant EP/W00187X/1. R.-J.S. also acknowledges funding from Trinity College, University of Cambridge. E.B. acknowledges the FNRS and the Excellence of Science program (EOS “ShapeME”, No. 40007525) funded by the FWO and F.R.S.-FNRS. Ph.G. acknowledges financial support from F.R.S.-FNRS Belgium (grant PROMOSPAN) and the European Union’s Horizon 2020 research and innovation program under grant agreement number 964931 (TSAR). The authors acknowledge the CECI supercomputer facilities funded by the F.R.S-FNRS (Grant No. 2.5020.1) and the Tier-1 supercomputer of the Fédération Wallonie-Bruxelles funded by the Walloon Region (Grant No. 1117545).
description: Funder: University of Liege, IPD-STEMA fellowship St. John’s College, University of Cambridge
description: Out-of-plane polar domain structures have recently been discovered in strained and twisted bilayers of inver- sion symmetry broken systems such as hexagonal boron nitride. Here we show that this symmetry breaking also gives rise to an in-plane component of polarization, and the form of the total polarization is determined purely from symmetry considerations. The in-plane component of the polarization makes the polar domains in strained and twisted bilayers topologically non-trivial, forming a network of merons and antimerons (half-skyrmions and half-antiskyrmions). For twisted systems, the merons are of Bloch type whereas for strained systems they are of Ne ́el type. We propose that the polar domains in strained or twisted bilayers may serve as a platform for exploring topological physics in layered materials and discuss how control over topological phases and phase transitions may be achieved in such systems.
description: D. B. acknowledges funding from the University of Lie ́ge under special funds for research (IPD-STEMA fellowship programme) and St. John’s College, University of Cambridge. R. J. S and G. C. acknowledge funding from a New Investi- gator Award, EPSRC grant EP/W00187X/1. R. J. S also ac- knowledges funding from Trinity College, University of Cam- bridge. E. B. acknowledges the FNRS and the Excellence of Science program (EOS “ShapeME”, No. 40007525) funded by the FWO and F.R.S.-FNRS. Ph. G. acknowledges financial support from F.R.S.-FNRS Belgium (grant PROMOSPAN) and the European Union’s Horizon 2020 research and innova- tion program under grant agreement number 964931 (TSAR). The authors acknowledge the CECI supercomputer facilities funded by the F.R.S-FNRS (Grant No. 2.5020.1) and the Tier- 1 supercomputer of the Fe ́de ́ration Wallonie-Bruxelles funded by the Walloon Region (Grant No. 1117545).
Multiplexed Electrochemical Sensors Based on Printed Circuit Board
Creators: name: Zhang, Zhehao
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: Electrochemical sensors are widely used in all fields of scientific and industrial analyses. Ion-selective electrodes (ISE) are potentiometric sensors that measure activities of ions and ionic species. These sensors reply on ionophores/ion-exchanging membrane for selectivity and liquid inner reference for ion-to-electron transduction. However, conventional ISEs are primarily used in laboratory settings due to fragility and routine maintenance. In recent years, development of solid-contact ISEs (SCISE) has shown promise to permit sensors to be taken out of the lab for point-of-need or point-of-care applications, including clinical diagnostics, wearable devices, precision agriculture, and in situ environmental monitoring. However, long-term, multi-analyte measurements remain difficult owing to challenges associated with sensor stability, cost of material and automation. In this work, we demonstrated multiplexed, cost-effective SCISEs that are suitable for long-term, standalone measurements. We used mesoporous carbon black (MCB) as a low-cost, readily available solid contact material for ion-to-electron transduction, which substantially improved sensor stability. With MCB, we developed a novel method of fabricating multiplexed SCISEs using printed-circuit board (PCB). PCB technology offers a viable alternative to existing techniques with unparalleled upscaling capability. To enable continuous and automatic analysis, we developed an integrated system that supports sensor readout and, most importantly, the ability to re-calibrate sensor in situ. Finally, we explored applications of the sensor system in complex samples, including plant sap, cell culture media, and artificial saliva. The results here demonstrate that the multiplexed sensing platform can provide a reliable, versatile tool with substantial potential for a variety of point-of-need or point-of-care applications.
Designing innovative local water governance using a living lab: Wadi el Bey Case study - Tunisia
Creators: name: Mellah Thuraya
name: Baccouche Hatem
name: Jellali Salah
name: Karatzas George, P.
name: Roggero Pier Paolo
name: Akrout Hanene
Publisher: name: Zenodo
Year: 2022
Subjects: innovative governance, sustainability, living lab, Wadi el Bey

description: In this work, the living lab is used to co-design innovative institutional arrangements to
 govern and sustainably manage local water resources. The co-creation process is carried out
 according to a decentralized participatory and actor-centered approach and using the social
 learning concept. The stakeholders involved in water management, including local authorities,
 users, citizens and researchers, are brought together to analyse the sustainability issues of
 the social-ecological system at the Wadi El Bey watershed level. The researchers have
 designed the Wadi el Bey living lab as a social arena where the local actors can meet. At the
 first stage of this process, and until the consensus on the new governance is reached, the
 actors are guided via various activities such as participatory mapping, inversing role, and
 expressing motivations and expectations. These interactive activities aimed to build a
 relevant, comprehensive, and common vision on the issues related to the management of
 local groundwater resources.
Tyrosine partners coordinate DNA nicking by the Salmonella typhimurium plasmid pCU1 relaxase enzyme
Creators: name: Niblock, Franklin C.
name: Redinbo, Matthew R.
name: Nash, Rebekah P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Conjugative plasmid transfer results in the spread of antibiotic resistance genes and virulence factors between bacterial cells. Plasmid transfer is dependent upon the DNA nicking activity of a plasmid-encoded relaxase enzyme. Tyrosine residues within the relaxase cleave the DNA plasmid nic site in a highly sequence-specific manner. The conjugative resistance plasmid pCU1 encodes a relaxase with four tyrosine residues surrounding its active site (Y18,19,26,27). We use activity assays to demonstrate that the pCU1 relaxase preferentially uses Y26 or a combination of Y18+19 to nick DNA at wild type levels, and that an adjacent aspartic acid deprotonates these tyrosines to activate them for attack. Our findings illustrate the unique modifications that the pCU1 relaxase has introduced into the traditional relaxase-mediated DNA nicking mechanism.
MPEC 2023-U134 : 2023 UR2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 UR2

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
​SEED:​ ​Towards​ ​a​ ​Shared​ ​Evaluation​ ​Environment​ ​for​ ​Software-Defined-Networking Applications
Creators: name: König, Michael
name: Neumeister, Felix
name: Dittebrandt, Addis
Publisher: name: Karlsruher Institut für Technologie (KIT)
Year: 2017
Subjects: networking
sdn
software-defined-networking
reproducibility

description: Software-Defined-Networking (SDN) is an ongoing topic in the networking-community. Despite this, the evaluation of SDN-applications is still a nontrivial task. Researches need to study the evaluation environment as well as create fitting scenarios. This process is time consuming and error prone. Furthermore, the issue of reproducibility is gaining traction in the community as many publications are not reproducible. We present SEED, a Shared Evaluation Environment for SDN-applications. SEED separates applications, scenarios and simulators from each other. For this, it leverages the OpenFlow interface and introduces a description format for simulation scenarios. These scenarios are parsed by an adapter interface for three supported simulators. SEED aids researchers by enabling easy reuse of scenarios and by addressing simulators with a unified interface. Further, a clear experiment specification aids to simplify reproducibility.
Diffeomorphic density matching by optimal information transport
Creators: name: Bauer, Martin
name: Joshi, Sarang
name: Modin, Klas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 58E50, 49Q10, 58E10

description: We address the following problem: given two smooth densities on a manifold, find an optimal diffeomorphism that transforms one density into the other. Our framework builds on connections between the Fisher-Rao information metric on the space of probability densities and right-invariant metrics on the infinite-dimensional manifold of diffeomorphisms. This optimal information transport, and modifications thereof, allows us to construct numerical algorithms for density matching. The algorithms are inherently more efficient than those based on optimal mass transport or diffeomorphic registration. Our methods have applications in medical image registration, texture mapping, image morphing, non-uniform random sampling, and mesh adaptivity. Some of these applications are illustrated in examples.
description: 35 pages
MPEC 2023-U135 : 2023 US2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 US2

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Scoping review of clinical practice guidelines for consciousness disorders: A scoping review protocol
Creators: name: Alva-Diaz, Carlos
name: Cabanillas-Lazo, Miguel
name: Castillo-Gutierrez, Piero
name: Pascual-Guevara, Milagros
name: Pais-Lescano, Aura
name: Fernandez-Medina, Diego
Publisher: name: figshare
Year: 2022
Subjects: Medicine

description: We aimed to make a scoping review to characterize and evaluate the quality of the clinical practice guidelines (CPGs) for diagnosis and management for patients with any type of consciousness disorders (CD). Also, we aimed to summarize and assessment recommendations among CPGs.
Supplementary Material for CommunityTapestry: A Dynamic Real-Time Dashboard to Signal Diversity and Turnover in Open Source Communities
Creators: name: Anonymized
Publisher: name: Zenodo
Year: 2023

description: This supplementary material contains the study scripts, study questionnaire, pre and post-study surveys, and the dashboard interfaces related to the paper CommunityTapestry: A Dynamic Real-Time Dashboard to Signal
 Diversity and Turnover in Open Source Communities (ICSE 2024.
The genetic code as expressed through relationships between mRNA structure and protein function
Creators: name: Weeks, Kevin M.
name: Mauger, David M.
name: Siegfried, Nathan A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Structured RNA elements within messenger RNA often direct or modulate the cellular production of active proteins. As reviewed here, RNA structures have been discovered that govern nearly every step in protein production: mRNA production and stability; translation initiation, elongation, and termination; protein folding; and cellular localization. Regulatory RNA elements are common within RNAs from every domain of life. This growing body of RNA-mediated mechanisms continues to reveal new ways in which mRNA structure regulates translation. We integrate examples from several different classes of RNA structure-mediated regulation to present a global perspective that suggests that the secondary and tertiary structure of RNA ultimately constitutes an additional level of the genetic code that both guides and regulates protein biosynthesis.
The three giri of Paradiso XXXIII
Creators: name: Saiber, Arielle
name: Mbirika, Aba
Publisher: name: arXiv
Year: 2015
Subjects: subject: History and Overview (math.HO)
subject: FOS: Mathematics
subject: 01A02, 00A02

description: Our paper offers an analysis of how Dante describes the tre giri ("three rings") of the Holy Trinity in Paradiso 33 of the Divine Comedy. We point to the myriad possibilities Dante may have been envisioning when he describes his vision of God at this final stage in his journey. Saiber focuses on the features of shape, motion, size, color, and orientation that Dante details in describing the Trinity. Mbirika uses mathematical tools from topology (specifically, knot theory) and combinatorics to analyze all the possible configurations that have a specific layout of three intertwining circles which we find particularly compelling given Dante's description of the Trinity: the round figures arranged in a triangular format with rotational and reflective symmetry. Of the many possible link patterns, we isolate two particularly suggestive arrangements for the giri: the Brunnian link and the (3,3)-torus link. These two patterns lend themselves readily to a Trinitarian model.
description: This interdisciplinary project merges Medieval Italian literature and mathematics. Though there is no category on arXiv for such joint research, the authors want to make this available to mathematicians. The editors of the journal Dante Studies have given us permission to post our published work here. NOTE: All figures are in the last pages of the article, as per the journal's formatting
Contribution of protein phosphorylation to binding-induced folding of the SLBP-histone mRNA complex probed by phosphorus-31 NMR
Creators: name: Thapar, Roopa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Graphical abstractHighlights•SLBP is an intrinsically disordered protein (IDP) in the absence of RNA.•A phosphothreonine in the SLBP RNA-binding domain stabilizes the SLBP–histone mRNA complex.•This phosphate exhibits torsional strain as revealed by its 31P NMR chemical shift.•Phosphates can play structural roles in stabilizing tertiary structure in IDPs.•31P NMR can be a good spectroscopic probe for folding of phosphorylated IDPs.Phosphorus-31 (31P) NMR can be used to characterize the structure and dynamics of phosphorylated proteins. Here, I use 31P NMR to report on the chemical nature of a phosphothreonine that lies in the RNA binding domain of SLBP (stem-loop binding protein). SLBP is an intrinsically disordered protein and phosphorylation at this threonine promotes the assembly of the SLBP–RNA complex. The data show that the 31P chemical shift can be a good spectroscopic probe for phosphate-coupled folding and binding processes in intrinsically disordered proteins, particularly where the phosphate exhibits torsional strain and is involved in a network of hydrogen-bonding interactions.
PRIVATEER Deliverable D2.2: Use cases, requirements and design report
Creators: name: Pastor, Antonio
name: Ramon, Hugo
name: Lopez, Diego
Publisher: name: Zenodo
Year: 2023

description: This deliverable identifies use cases for privacy-preserving security in 5G/6G, lists the requirements and describes the architecture for the PRIVATEER security framework. The functionality of key components for privacy-first security is described in detail.
Precision calculations of nucleon charges $g_A$, $g_S$, $g_T$
Creators: name: Gupta, Rajan
name: Bhattacharya, Tanmoy
name: Joseph, Anosh
name: Lin, Huey-Wen
name: Yoon, Boram
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We present a detailed analysis of statistical and systematic errors in the calculation of matrix elements of iso-vector scalar, axial and tensor charges between a neutron and a proton state. These analyses are being done on dynamical $N_f=2+1+1$ HISQ configurations generated by the MILC Collaboration using valence clover fermions. Using ensembles at three values of the lattice spacing ($a=0.12,\ 0.09,$ and $0.06$ fm) and three values of the quark mass ($M_π\approx 310,\ 220$ and $130$ MeV) we find that the estimates of the tensor charge are stable and it can be extracted with $5\%$ precision with O(10,000) measurements. We also find that higher statistics are needed to resolve the various uncertainties in the calculation of $g_A$ and improve the signal in $g_S$, which with present data has large errors. A brief status report on the mixing and renormalization of novel operators contributing to nEDM is also given.
description: 7 pages 7 figures, Talk at Lattice 2014
Evaluation of Pelvic Floor Symptoms and Sexual Function in Primiparous Women Who Underwent Operative Vaginal Delivery Versus Cesarean Delivery for Second-Stage Arrest
Creators: name: Geller, Elizabeth J.
name: Ju, Rujin
name: Myers, Erinn
name: Matthews, Catherine A.
name: Crane, Andrea K.
name: Bane, Heather
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: This study aimed to compare the prevalence and severity of pelvic floor symptoms and sexual function at 1 year postpartum in women who underwent either operative vaginal delivery (OVD) or cesarean delivery (CD) for second-stage arrest.
Obstetric Sphincter Injury Interacts With Diarrhea and Urgency to Increase the Risk of Fecal Incontinence in Women With Irritable Bowel Syndrome
Creators: name: Robinson, Barbara L.
name: Lin, Feng-Chang
name: Parnell, Brent
name: Turner, Marsha
name: Crane, Andrea
name: Jannelli, Mary
name: Geller, Elizabeth
name: Matthews, Catherine A.
name: Connolly, AnnaMarie
name: Palsson, Olafur S.
name: Wells, Ellen
name: Whitehead, William E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: To confirm that fecal urgency and diarrhea are independent risk factors for fecal incontinence (FI), to identify obstetrical risk factors associated with FI in women with IBS (irritable bowel syndrome), and to determine whether obstetric anal sphincter injuries interact with diarrhea or urgency to explain the occurrence of FI.
Kriterien: Kirchliche Friedensethik nach dem Urteil vom 12. Juli
Creators: name: Ruh, Ulrich
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 48 Nr. 8 (1994): Herder Korrespondenz, Band 48, Heft 8
Numerical Optimization of a Microfluidic System for Hydrodynamic Trapping of Tumor Cells
Creators: name: Cardona, Sara
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: Liquid biopsy is a highly effective microfluidic technique for isolating circulating tumor cells and cell-free DNA from the blood of cancer patients. Physical trapping is a label-free isolation approach that relies on cell size as a selective phenotype to improve cell isolation in liquid biopsy or to retain target cells on-chip for follow-on analysis and imaging. In silico models have been extensively used to optimize the design of the hydrodynamic trapping microfluidic device and to investigate cancer cell transmigration through narrow constrictions. While most studies focus on computational fluid dynamics (CFD) analysis of flow over particle and (or) pillar, a quantitative analysis of mechanical interaction between particle and trapping unit is missing and the literature which provides similar analysis centers on longitudinally extended geometries (e.g., micro-vessels) usually for the purpose of understanding a biological phenomenon, rather than designing a trapping apparatus. This work defines an experimentally informed description of critical pressure as a function of cell morphology and trapping unit geometry. Our findings show that a hyper-elastic definition accurately captures the stress-related softening behavior observed in cancer cells passing through microconstrictions. These findings were used to develop a model capable of predicting and extrapolating critical pressure values. The validity of the model was assessed with both regression analysis and experimental data. Coupled with CFD analysis, one can use this formulation to design efficient microfluidic devices for cell trapping and potentially perform downstream analysis of trapped cells.
Virulence strategies of the dominant USA300 lineage of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)
Creators: name: Joshi, Gauri S.
name: Thurlow, Lance R.
name: Richardson, Anthony R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Methicillin-Resistant Staphylococcus aureus (MRSA) poses a serious threat to worldwide health. Historically, MRSA clones have strictly been associated with hospital settings and most hospital-associated MRSA (HA-MRSA) disease resulted from a limited number of virulent clones. Recently, MRSA has spread into the community causing disease in otherwise healthy people with no discernible contact with healthcare environments. These community-associated (CA-MRSA) are phylogenetically distinct from traditional HA-MRSA clones and CA-MRSA strains seem to exhibit hyper virulence and more efficient host:host transmission. Consequently, CA-MRSA clones belonging to the USA300 lineage have become dominant sources of MRSA infections in North America. The rise of this successful USA300 lineage represents an important step in the evolution of emerging pathogens and a great deal of effort has been exerted to understand how these clones evolved. Here we review much of the recent literature aimed at illuminating the source of USA300 success and broadly categorize these findings into three main categories: newly acquired virulence genes, altered expression of common virulence determinants and alterations in protein sequence that increase fitness. We argue that none of these evolutionary events alone account for the success of USA300, but rather their combination may be responsible for the rise and spread of CA-MRSA.
Rigidity and stability of spheres in the Helfrich model
Creators: name: Bernard, Yann
name: Wheeler, Glen
name: Wheeler, Valentina-Mira
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: Differential Geometry (math.DG)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 74K15, 51P05, 00A71

description: The Helfrich functional, denoted by H^{c_0}, is a mathematical expression proposed by Helfrich (1973) for the natural free energy carried by an elastic phospholipid bilayer. Helfrich theorises that idealised elastic phospholipid bilayers minimise H^{c_0} among all possible configurations. The functional integrates a spontaneous curvature parameter c_0 together with the mean curvature of the bilayer and constraints on area and volume, either through an inclusion of osmotic pressure difference and tensile stress or otherwise. Using the mathematical concept of embedded orientable surface to represent the configuration of the bilayer, one might expect to be able to adapt methods from differential geometry and the calculus of variations to perform a fine analysis of bilayer configurations in terms of the parameters that it depends upon. In this article we focus upon the case of spherical red blood cells with a view to better understanding spherocytes and spherocytosis. We provide a complete classification of spherical solutions in terms of the parameters in the Helfrich model. We additionally present some further analysis on the rigidity and stability of spherocytes.
description: 32 pages
Polyphenol-rich sorghum brans alter colon microbiota and impact species diversity and species richness after multiple bouts of dextran sodium sulfate-induced colitis
Creators: name: Sturino, Joseph M.
name: Turner, Nancy D.
name: Ritchie, Lauren E.
name: Azcarate-Peril, M. Andrea
name: Rooney, Lloyd W.
name: Carroll, Raymond J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The microbiota affects host health, and dysbiosis is involved in colitis. Sorghum bran influences butyrate concentrations during dextran sodium sulfate (DSS) colitis, suggesting microbiota changes. We aimed to characterize the microbiota during colitis, and ascertain if polyphenol-rich sorghum bran diets mitigate these effects. Rats (n = 80) were fed diets containing 6% fiber from cellulose, or Black (3-deoxyanthocyanins), Sumac (condensed tannins), or Hi Tannin black (both) sorghum bran. Inflammation was induced three times using 3% DSS for 48 h (40 rats, 2 week separation), and the microbiota characterized by pyrosequencing. The Firmicutes/Bacteroidetes ratio was higher in Cellulose DSS rats. Colonic injury negatively correlated with Firmicutes, Actinobacteria, Lactobacillales and Lactobacillus, and positively correlated with Unknown/Unclassified. Post DSS#2, richness was significantly lower in Sumac and Hi Tannin black. Post DSS#3 Bacteroidales, Bacteroides, Clostridiales, Lactobacillales and Lactobacillus were reduced, with no Clostridium identified. Diet significantly affected Bacteroidales, Bacteroides, Clostridiales and Lactobacillus post DSS#2 and #3. Post DSS#3 diet significantly affected all genus, including Bacteroides and Lactobacillus, and diversity and richness increased. Sumac and Hi Tannin black DSS had significantly higher richness compared to controls. Thus, these sorghum brans may protect against alterations observed during colitis including reduced microbial diversity and richness, and dysbiosis of Firmicutes/Bacteroidetes.
A logistic model for the prediction of endometriosis
Creators: name: Sinaii, Ninet
name: Hartmann, Katherine E.
name: Segars, James
name: Stegmann, Barbara J.
name: Nieman, Lynnette K.
name: Stratton, Pamela
name: Funk, Michele Jonsson
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: To develop a model using individual and lesion characteristics to help surgeons choose lesions with a high probability of containing histologically-confirmed endometriosis.
Steady-state photoconductivity and multi-particle interactions in rubrene single crystals
Creators: name: Irkhin, P.
name: Najafov, H.
name: Podzorov, V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We demonstrate that photoconductivity of pristine rubrene crystals exhibits several distinct regimes, in which photocurrent as a function of cw (continuous wave) excitation intensity is described by a power law with exponents sequentially taking values 1, 1/3 and 1/4. We show that this photocurrent is generated almost exclusively at the surface of pristine rubrene crystals, while the bulk photocurrent is dramatically smaller and follows a different set of exponents, 1 and 1/2. A model based on exciton fission, fusion and triplet-charge quenching is developed to describe these non-trivial effects in photoconductivity of highly ordered organic semiconductors.
description: 15 pages, 3 figures, plus supplementary materials
Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort
Creators: name: Rossing, Mary Anne
name: Fridley, Brooke L.
name: Pike, Malcolm C.
name: Berchuck, Andrew
name: Moorman, Patricia G.
name: Templeman, Claire
name: Vierkant, Robert A.
name: Vitonis, Allison F.
name: Chenevix-Trench, Georgia
name: Cunningham, Julie M.
name: Gentry-Maharaj, Aleksandra
name: Terry, Kathryn L.
name: Pearce, Celeste Leigh
name: Schildkraut, Joellen M.
name: Palmieri, Rachel T.
name: Wu, Anna H.
name: Ness, Roberta B.
name: Near, Aimee M.
name: Webb, Penelope M.
name: Kjær, Susanne Krüger
name: Doherty, Jennifer A.
name: Menon, Usha
name: Hogdall, Estrid
name: Cramer, Daniel W.
name: Ramus, Susan J.
name: Goode, Ellen L.
name: Gayther, Simon A.
name: Moysich, Kirsten
name: Van Den Berg, David J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: To investigate the association between self-reported endometriosis and the putative functional promoter +331C/T single nucleotide polymorphism (SNP) and the PROGINS allele.
Tretminen: Wie wichtig sind die zweitwichtigsten Dinge in der Kirche?
Creators: name: Nientiedt, Klaus
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 48 Nr. 8 (1994): Herder Korrespondenz, Band 48, Heft 8
Short-term change in growth of uterine leiomyoma: tumor growth spurts
Creators: name: Garrett, Tiana A.
name: Peddada, Shyamal D.
name: Laughlin, Shannon K.
name: Semelka, Richard C.
name: Davis, Barbara
name: Day Baird, Donna
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: To describe the short-term changes in growth of uterine leiomyomata (fibroids).
Quantum++: A modern C++ quantum computing library
Creators: name: Gheorghiu, Vlad
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Quantum++ is a modern general-purpose multi-threaded quantum computing library written in C++11 and composed solely of header files. The library is not restricted to qubit systems or specific quantum information processing tasks, being capable of simulating arbitrary quantum processes. The main design factors taken in consideration were the ease of use, portability, and performance. The library's simulation capabilities are only restricted by the amount of available physical memory. On a typical machine (Intel i5 8Gb RAM) Quantum++ can successfully simulate the evolution of 25 qubits in a pure state or of 12 qubits in a mixed state reasonably fast. The library also includes support for classical reversible logic, being able to simulate classical reversible operations on billions of bits. This latter feature may be useful in testing quantum circuits composed solely of Toffoli gates, such as certain arithmetic circuits.
description: Replaced with the published version, 21 pages, 2 tables, 2 figures, all comments are welcome
The First Principles Study of Strongly Correlated Electronic Structure in Rare-Earth Nickelates
Creators: name: Liao, Xingyu
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: Rare earth nickelates attract numerous interests of research due to their rich physical properties and phase transitions. Here we report the electronic structures of LaNiO3 with oxygen vacancies using first principles. We find that LaNiO2.5 exhibits a ``site-selective" paramagnetic Mott insulating state at T~=290K as obtained using density functional theory plus dynamical mean field theory (DFT+DMFT). The Ni octahedron site develops a Mott insulating state with strong correlations as the Ni eg orbital is half-filled while the Ni square-planar site with apical oxygen vacancies becomes a band insulator. Moreover, we investigate the effects of the surface termination and the oxygen vacancy position on the electronic properties and vacancy energetics of LaNiO3 ultra-thin films under the compressive strain on the LaAlO3 substrate using DFT+U. The existence and positions of oxygen vacancies are found to be very sensitive to the termination of the film. In rare earth nickelates family, the LaNiO2, PrNiO2 and NdNiO2(ReNiO2) were found to be superconductive under hole doping. Their crystal structures have similarities with CaCuO2, which is also a superconductor under field-effect doping with high critical temperature. We also investigate the electronic structures of LaNiO2 and PrNiO2 with hole doping. We calculated the Hubbard U values of Ni 3d and Pr 4f orbitals using constrained DFT method. We found that the hole ions in LaNiO2 do not change the electronic structures and can be approximated by virtual crystal approximation. Doped holes in ReNiO2 partly distribute in Ni 3d orbitals, mainly in dx2-y2 orbitals. The effect of Pr 4f electrons on Ni 3d electrons is negligible, however it has weak effect on Pr 5d electrons at Fermi level.
MOESM1 of Diabetes care in remote Australia: the antenatal, postpartum and inter-pregnancy period
Creators: name: R. Kirkham
name: N. Trap-Jensen
name: J. Boyle
name: F. Barzi
name: E. L. M. Barr
name: C. Whitbread
name: P. Dokkum
name: M. Kirkwood
name: C. Connors
name: E. Moore
name: P. Zimmet
name: S. Corpus
name: A. Hanley
name: K. Oâ€™Dea
name: J. Oats
name: H. D. McIntyre
name: A. Brown
name: J. Shaw
name: L. Maple-Brown
Publisher: name: figshare
Year: 2019
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Survey, Survey of health care professionals in the NT.
Hot gaseous atmospheres in galaxy groups and clusters are both heated and cooled by X-ray cavities
Creators: name: Brighenti, Fabrizio
name: Mathews, William G.
name: Temi, Pasquale
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Expanding X-ray cavities observed in hot gas atmospheres of many galaxy groups and clusters generate shock waves and turbulence that are primary heating mechanisms required to avoid uninhibited radiatively cooling flows which are not observed. However, we show here that the evolution of buoyant cavities also stimulates radiative cooling of observable masses of low-temperature gas. During their early evolution, radiative cooling occurs in the wakes of buoyant cavities in two locations: in thin radial filaments parallel to the buoyant velocity and more broadly in gas compressed beneath rising cavities. Radiation from these sustained compressions removes entropy from the hot gas. Gas experiencing the largest entropy loss cools first, followed by gas with progressively less entropy loss. Most cooling occurs at late times, $\sim 10^8-10^9$ yrs, long after the X-ray cavities have disrupted and are impossible to detect. During these late times, slightly denser low entropy gas sinks slowly toward the centers of the hot atmospheres where it cools intermittently, forming clouds near the cluster center. Single cavities of energy $10^{57}-10^{58}$ ergs in the atmosphere of the NGC 5044 group create $10^8 - 10^9$ $M_{\odot}$ of cooled gas, exceeding the mass of extended molecular gas currently observed in that group. The cooled gas clouds we compute share many attributes with molecular clouds recently observed in NGC 5044 with ALMA: self-gravitationally unbound, dust-free, quasi-randomly distributed within a few kpc around the group center.
description: 12 pages, 11 figure; accepted for publication by ApJ
Which patients pursue fertility preservation treatments? A multicenter analysis of the predictors of fertility preservation in women with breast cancer
Creators: name: Mersereau, Jennifer E.
name: Oktay, Kutluk
name: Lee, Sanghoon
name: Morse, Christopher
name: Gracia, Clarisa
name: Kim, Jayeon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: To evaluate predictors of undergoing fertility preservation treatment (FPT) in women with breast cancer.