cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 3: of Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial
Creators: name: Yuanyuan Wang
name: Shimmin, Andrew
name: Ghosh, Peter
name: Marks, Paul
name: Linklater, James
name: Connell, David
name: Hall, Stephen
name: Skerrett, Donna
name: Itescu, Silviu
name: Cicuttini, Flavia
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Computational Biology

description: Table S3. Baseline characteristics of completers and non-completers at 24 months. (DOC 32 kb)
BindingDB Entry 50020364: Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Nuclear receptor subfamily 4 group A member 2, Ludwig Maximilian University of Munich, Affinity

description: Small molecule binding data for protein Nuclear receptor subfamily 4 group A member 2, Uniprot P43354
Additional file 4: of Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial
Creators: name: Yuanyuan Wang
name: Shimmin, Andrew
name: Ghosh, Peter
name: Marks, Paul
name: Linklater, James
name: Connell, David
name: Hall, Stephen
name: Skerrett, Donna
name: Itescu, Silviu
name: Cicuttini, Flavia
Publisher: name: Figshare
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Computational Biology

description: Table S4. Change from baseline in KOOS scores over 24 months. (DOC 46 kb)
BindingDB Entry 50020363: Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Mitogen-activated protein kinase 7, Peking University, Affinity

description: Small molecule binding data for protein Mitogen-activated protein kinase 7, Uniprot Q13164
Additional file 1: of Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial
Creators: name: Yuanyuan Wang
name: Shimmin, Andrew
name: Ghosh, Peter
name: Marks, Paul
name: Linklater, James
name: Connell, David
name: Hall, Stephen
name: Skerrett, Donna
name: Itescu, Silviu
name: Cicuttini, Flavia
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Computational Biology

description: Table S1. Baseline characteristics of completers and non-completers at 6 months. (DOC 32 kb)
Additional file 2: of Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial
Creators: name: Yuanyuan Wang
name: Shimmin, Andrew
name: Ghosh, Peter
name: Marks, Paul
name: Linklater, James
name: Connell, David
name: Hall, Stephen
name: Skerrett, Donna
name: Itescu, Silviu
name: Cicuttini, Flavia
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Computational Biology

description: Table S2. Baseline characteristics of completers and non-completers at 12 months. (DOC 32 kb)
BindingDB Entry 50020361: Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: RAC-alpha serine/threonine-protein kinase, Rho-associated protein kinase 1, and Rho-associated protein kinase 2, Zhejiang University, Affinity

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase, Rho-associated protein kinase 1, and Rho-associated protein kinase 2, Uniprot O75116, P31749, and Q13464
BindingDB Entry 50020360: Design of a structure-activity relationship model of vitamin K epoxide reductase (VKORC1) inhibitors combining chemical synthesis of new compounds, enzymatic assays and molecular modelling.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Vitamin K epoxide reductase complex subunit 1, University of Lyon, Affinity

description: Small molecule binding data for protein Vitamin K epoxide reductase complex subunit 1, Uniprot Q9BQB6
BindingDB Entry 50020359: Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Short transient receptor potential channel 5, Chinese Academy of Sciences, Affinity

description: Small molecule binding data for protein Short transient receptor potential channel 5, Uniprot Q9UL62
BindingDB Entry 50020358: Discovery of the Potent and Selective Inhaled Janus Kinase 1 Inhibitor AZD4604 and Its Preclinical Characterization.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Astrazeneca, Affinity

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, and P52333
BindingDB Entry 50020357: Unlocking DCAFs To Catalyze Degrader Development: An Arena for Innovative Approaches.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: DNA damage-binding protein 1, Baylor College of Medicine, Affinity

description: Small molecule binding data for protein DNA damage-binding protein 1, Uniprot Q16531
BindingDB Entry 50020356: Synthesis and Validation of the First Cell-Impermeable Hsp90α-Selective Inhibitors.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Endoplasmin, Heat shock protein 75 kDa, mitochondrial, Heat shock protein HSP 90-alpha, and Heat shock protein HSP 90-beta, The University of Notre Dame, Affinity

description: Small molecule binding data for protein Endoplasmin, Heat shock protein 75 kDa, mitochondrial, Heat shock protein HSP 90-alpha, and Heat shock protein HSP 90-beta, Uniprot P07900, P08238, P14625, and Q12931
BindingDB Entry 50020355: Molecular Design of Cyclic Peptides with Cell Membrane Permeability and Development of MDMX-p53 Inhibitor.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Protein Mdm4, Fujifilm, Affinity

description: Small molecule binding data for protein Protein Mdm4, Uniprot O15151
BindingDB Entry 50020354: Dose-Response Activity-Based DNA-Encoded Library Screening.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Coagulation factor X and Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, The Scripps Research Institute, Affinity

description: Small molecule binding data for protein Coagulation factor X and Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Uniprot P00742 and Q13822
Myrianida tereseta Hoagland 1920
Creators: name: Nygren, Arne
Publisher: name: Zenodo
Year: 2004
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Polychaeta
Phyllodocida
Syllidae
Myrianida
Myrianida tereseta

description: Myrianida tereseta Hoagland, 1920 (Fig. 54 A–E)
Myrianida tereseta Hoagland, 1920: 603 –604, pl. 46, fig. 1–3.
Material examined. Philippine: holotype USNM 18942 (female stolon), Ticao Island, San Miguel Harbor, Philippine Expedition 1907–1910.
Description. Type incomplete in several parts. Length c. 15 mm for 6+35+70 chaetigers, width 0.4 mm in region a excluding parapodial lobes, width in region b 1 mm including parapodial lobes. Preserved material yellowish, without colour markings (Fig. 54C); body filled with eggs. Ciliation not possible to assess.
Prostomium wider than long, anterior margin concave (Fig. 54A, B). Four eyes, with lenses, situated on ventral and dorsal side of prostomium; ventral pair much larger (Fig. 54A, B). Palps absent. Nuchal epaulettes reaching beginning of chaetiger 1.
Median and lateral antennae, inserted on anterior margin of prostomium (Fig. 54A), equal in length to prostomial width; median antenna slightly longer. Tentacular cirri 2 pairs (Fig. 54B); dorsal pair as long as 1/2 prostomial width, ventral pair 1/3 as long as dorsal. First dorsal cirri, equal in length to antennae, longer than following dorsal cirri; achaetous knobs present (Fig. 54B). Second dorsal cirri situated above first chaetigerous lobes. Cirri in region a reciprocally equal, in length equal to body width; cirri in region b equal in length to cirri in region a, without any alternation in length (Fig. 54C); cirri in region c diminishing regularly towards the end. Cirrophores absent.
Parapodia in region a, and c with rounded conical neuropodial lobes, of small to medium size; parapodia in region b, slightly larger than in region a, with additional notopodial lobes. Single neuropodial acicula in all chaetigers; 2 anterodorsal and 4 thick and 4 thin posteroventral notoaciculae in region b. Neuropodial chaetal fascicle with c. 10 compounds in region a and b, 5–7 in region c. Compound chaetae with small distal tooth (Fig. 54D); serration present. Thin bayonet chaetae (Fig. 54E), subdistally denticulated, present in posterior chaetigers. Notopodial chaetal fascicle with 15–20 swimming chaetae. Posterior part lost.
Distribution. Central Pacific. Philippines. Only known from type specimen.
Remarks. It is not understood on what basis M. tereseta was referred to Myrianida, as all the appendages are cylindrical. In any case, M. tereseta is another stolon like A. obliquatus, and A. rostripalpus, with achaetous knobs, 6 chaetigers in region a, in combination with a thin bayonet chaetae. However, the distal tooth of the compound chaetae in M. tereseta is small, while large in A. obliquatus and A. rostripalpus. For the same reasons as discussed for A. obliquatus, and A. rostripalpus, M. tereseta is considered as Procerini incertae sedis.
description: Published as part of Nygren, Arne, 2004, Revision of Autolytinae (Syllidae: Polychaeta)., pp. 1-314 in Zootaxa 680 on page 114, DOI: 10.5281/zenodo.157809
Reticulolaelaps Costa 1968
Creators: name: Joharchi, O.
name: Babaeian, E.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Laelapidae
Reticulolaelaps

description: Genus Reticulolaelaps Costa
Reticulolaelaps Costa, 1968: 26.
Type species: Reticulolaelaps faini Costa, 1968.
Diagnosis — The genus is characterised by a well sclerotised hypertrichous holodorsal shield, convex dorsal shield and flat venter, and a large genito-ventral shield, strongly expanded posterior to coxae IV, abutting the anal shield, bearing six pairs of setae, with strong reticulated ornamentation. Pre-sternal absent; female sternal shield deeply concave in posterior margin and lateral corners extended to the posterior level of coxa III, with three pairs of simple sternal setae; endopodal shields between coxae II and III fused with sternal shield. Metasternal setae st4 apparently absent; poroids iv3 present on the posterolateral extensions of sternal shield; exopodal plate behind coxa IV large and triangular, more or less contiguous with but separate from peritrematal shields and genitoventral shield; peritrematal shield extending posteriorly well past coxae IV; anal shield large and nearly twice as wide as long, cribrum relatively broad; opisthogastric membrane with five pairs of smooth setae; surface of epistome faintly reticulated, its anterior margin smooth, curved and well extended; chelicera with small and robust digits with few teeth. Hypostomal groove relatively narrow, with four rows of denticles on the anterior half of the groove, each bearing 2-5 small teeth; hypostome with two large membranous flaps near the insertion of corniculi. Corniculi relatively short, and somewhat membranous. All the sclerotised parts of the body are well ornamented throughout, including the legs. Legs significantly shorter than idiosoma, genu III (2 2/1 2/0 1) and IV (2 2/1 3/1 1) with eight and ten setae respectively. Male with sterno-genitiventral shield with ten pairs of setae, with separate anal shield similar to that of the female.
description: Published as part of Joharchi, O. & Babaeian, E., 2015, A new species of Reticulolaelaps Costa (Acari: Laelapidae) associated with Tapinoma sp. (Hymenoptera: Formicidae) from Iran, with a review of the world species, pp. 33-40 in Acarologia 55 (1) on page 34, DOI: 10.1051/acarologia/20152146, http://zenodo.org/record/4640113
BindingDB Entry 50020352: PARP7 Inhibition: A Promising Pathway to Advancements in Cancer Therapy.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Protein mono-ADP-ribosyltransferase TIPARP, Usona Institute, Affinity

description: Small molecule binding data for protein Protein mono-ADP-ribosyltransferase TIPARP, Uniprot Q7Z3E1
MOESM1 of A novel transcription factor specifically regulates GH11 xylanase genes in Trichoderma reesei
Creators: name: Liu, Rui
name: Chen, Ling
name: Yanping Jiang
name: Zou,
name: Zhihua Zhou
Publisher: name: Figshare
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 1. Putative specific xylanase transcription factors in T. reesei.
MOESM1 of A novel transcription factor specifically regulates GH11 xylanase genes in Trichoderma reesei
Creators: name: Liu, Rui
name: Chen, Ling
name: Yanping Jiang
name: Zou,
name: Zhihua Zhou
Publisher: name: Figshare
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 1. Putative specific xylanase transcription factors in T. reesei.
Leptotrombidium (Leptotrombidium) longisetum
Creators: name: Nielsen, David H.
name: Robbins, Richard G.
name: Rueda, Leopoldo M.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Actinedida
Trombiculidae
Leptotrombidium
Leptotrombidium longisetum

description: Leptotrombidium (Leptotrombidium) longisetum (Womersley, 1952):
ORI
Trombicula (Leptotrombidium) longiseta Womersley 1952
Leptotrombidium longiseta, Radford 1954 a
Leptotrombidium (Leptotrombidium) longisetum, Vercammen-Grandjean & Langston 1976; Yu et al. 1982 Leptotrombidium longisetum, Stekolnikov 2013 [longisetum group], 2021
description: Published as part of Nielsen, David H., Robbins, Richard G. & Rueda, Leopoldo M., 2021, Annotated world checklist of the Trombiculidae and Leeuwenhoekiidae (1758 - 2021) (Acari: Trombiculoidea), with notes on nomenclature, taxonomy, and distribution, pp. 1-243 in Zootaxa 4967 (1) on page 133, DOI: 10.11646/zootaxa.4967.1.1, http://zenodo.org/record/4745510
Additional file 8: Fig. S3. of Feed-additive probiotics accelerate yet antibiotics delay intestinal microbiota maturation in broiler chicken
Creators: name: Pengfei Gao
name: Ma, Chen
name: Sun, Zheng
name: Lifeng Wang
name: Huang, Shi
name: Xiaoquan Su
name: Xu, Jian
name: Heping Zhang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: KEGG metabolic pathways that differentiate the antibiotics group (or the probiotics group) from the control group. (PDF 2683Â kb)
BindingDB Entry 50020351: Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2).
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Mitogen-activated protein kinase 1 and Platelet-derived growth factor receptor alpha/beta, Genentech, Affinity

description: Small molecule binding data for protein Mitogen-activated protein kinase 1 and Platelet-derived growth factor receptor alpha/beta, Uniprot P05622, P26618, and P28482
BindingDB Entry 50020348: Novel Compounds as TEAD Inhibitors for Treating Cancer.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Transcriptional enhancer factor TEF-1, Transcriptional enhancer factor TEF-3, Transcriptional enhancer factor TEF-4, and Transcriptional enhancer factor TEF-5, Smith, Gambrell & Russell, Affinity

description: Small molecule binding data for protein Transcriptional enhancer factor TEF-1, Transcriptional enhancer factor TEF-3, Transcriptional enhancer factor TEF-4, and Transcriptional enhancer factor TEF-5, Uniprot P28347, Q15561, Q15562, and Q99594
Autolytini Grube 1850
Creators: name: Nygren, Arne
Publisher: name: Zenodo
Year: 2004
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Polychaeta
Phyllodocida
Syllidae

description: Autolytini Grube, 1850
Linnean named definition. Type genus Autolytus Grube, 1850. PhyloCode definition. No name definition provided. The name Autolytini is reduntant as Myrianida refers to the same clade.
Apomorphies. See Myrianida.
description: Published as part of Nygren, Arne, 2004, Revision of Autolytinae (Syllidae: Polychaeta)., pp. 1-314 in Zootaxa 680 on page 115, DOI: 10.5281/zenodo.157809
Additional file 4: of Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
Creators: name: Wang, Lin
name: Xiaozhong Li
name: Louxin Zhang
name: Gao, Qiang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: 110309 Infectious Diseases

description: Prediction performance comparisons of four methods for the drugs targeting genes in the ERK pathway with respect to two measurements. A) Pearson correlation coefficient between predicted and observed response values of sensitive and resistant cell lines for each drug. B) Root mean squared error between predicted and observed drug responses of sensitive and resistant cell lines for each drug. (PDF 381 kb)
BindingDB Entry 50020347: Discovery of Novel, Thienopyridine-Based Tyrosine Kinase Inhibitors Targeting Tumorigenic RON Splice Variants.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Hepatocyte growth factor receptor and Macrophage-stimulating protein receptor, Wellmarkerbio Co., Affinity

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Macrophage-stimulating protein receptor, Uniprot A0A024R759, P08581, and Q04912
BindingDB Entry 50020346: New Horizons in Cancer Treatment: A Closer Look at Novel PI3Kα Inhibitors.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Usona Institute, Affinity

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Uniprot P42336
Pseudoparasitus lativentris
Creators: name: Joharchi, O.
name: Babaeian, E.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Laelapidae
Pseudoparasitus
Pseudoparasitus lativentris

description: Pseudoparasitus lativentris (Karg)
new combination
(Figure 3)
Reticulolaelaps lativentris Karg, 1978: 26.
Specimens examined — The two paratype specimens of Karg’s collection were examined by the first author: Slide ZMB Kat. Nr. 40559 ♀ and 40560 ♂, labelled Hypoaspis (Reticulolaelaps) lativentris Karg, 1978, paratypus, Chile Umgebung von La Union (Prov. Valdivia). Modrige Erde aus feucht. Wald in tief. Tal. 26.10.1965.
Notes — Here are morphological features of P. lativentris that complement the original description of Karg (1978): The dorsal shield with 39 pairs of setae 21 podonotal, 17 opisthonotal, including three pairs of Zx setae between J and Z setae, and four unpaired median Jx setae; setae increasing in length from anterior to posterior, except Z5, shorter than surrounding setae; most setae long enough to reach well past base of next posterior seta. Dorsal shield wrapping around onto the ventral idiosoma, forming a marginal strip, except for the caudal end of the idiosoma. Genito-ventral shield very wide, bearing four pair of setae (including st5), with truncate posterior margin, and its surface reticulated. Hypostomal groove wide, with six rows of denticles each bearing 6-10 very small teeth, except the first row with four teeth, and a smooth anterior transverse line (Fig. 3B). The palp tarsal claw has two pointed tines of unequal length; palp trochanter setae simple, needle-like. Genu IV with nine setae (2 2/1 3/0 1), anteroventral seta spine-like. Male with sternal, genital, endopodal, ventral and anal shields fused into a holoventral shield, with nine pairs of setae and four pairs of poroids, with strong reticulation throughout. Unpaired post-anal seta shorter than para-anal setae, cribrum small, paranal gland pores not visible (Fig. 3A).
description: Published as part of Joharchi, O. & Babaeian, E., 2015, A new species of Reticulolaelaps Costa (Acari: Laelapidae) associated with Tapinoma sp. (Hymenoptera: Formicidae) from Iran, with a review of the world species, pp. 33-40 in Acarologia 55 (1) on page 37, DOI: 10.1051/acarologia/20152146, http://zenodo.org/record/4640113
Additional file 4: of Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
Creators: name: Wang, Lin
name: Xiaozhong Li
name: Louxin Zhang
name: Gao, Qiang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Prediction performance comparisons of four methods for the drugs targeting genes in the ERK pathway with respect to two measurements. A) Pearson correlation coefficient between predicted and observed response values of sensitive and resistant cell lines for each drug. B) Root mean squared error between predicted and observed drug responses of sensitive and resistant cell lines for each drug. (PDF 381 kb)
BindingDB Entry 50020345: Novel Haloacethydrazides as AEP Inhibitors for Treating Alzheimer's Disease.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Legumain, Smith, Gambrell & Russell, Affinity

description: Small molecule binding data for protein Legumain, Uniprot Q99538
Ampithoidae Boeck 1871
Creators: name: Kodama, Masafumi
name: Kodama, Naoko
name: Mukaida, Yukiko
name: Hosoki, Takuya K.
name: Nakamoto, Kenta
name: Tanita, Iwao
name: Yamada, Hideaki
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Ampithoidae

description: Family Ampithoidae Boeck, 1871
[Japanese name: Higenaga-yokoebi-ka]
description: Published as part of Kodama, Masafumi, Kodama, Naoko, Mukaida, Yukiko, Hosoki, Takuya K., Nakamoto, Kenta, Tanita, Iwao & Yamada, Hideaki, 2024, First record of the genus Cymadusa Savigny, 1816 (Crustacea: Amphipoda: Ampithoidae) from Japan, with redescription and DNA barcoding for C. imbroglio Rabindranath, 1972, pp. 556-568 in Zootaxa 5551 (3) on page 558, DOI: 10.11646/zootaxa.5551.3.6, http://zenodo.org/record/14443217
BindingDB Entry 50020344: Design and Synthesis of 1,3,5-Triazines or Pyrimidines Containing Dithiocarbamate Moiety as PI3Kα Selective Inhibitors.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Shenyang Pharmaceutical University, Affinity

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329, P42336, P42338, and P48736
Additional file 3: of Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
Creators: name: Wang, Lin
name: Xiaozhong Li
name: Louxin Zhang
name: Gao, Qiang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Hematology

description: A set of simulated data used to evaluate the prediction performance of SRMF. Target drug responses, their perturbations with similarities of drugs and cell lines used as inputs for SRMF are simulated. Besides, an example for illustrating the efficiency of SRMF is described in detail. (PDF 185 kb)
BindingDB Entry 50020343: Brain-penetrant cyanoindane and cyanotetralin inhibitors of G2019S-LRRK2 kinase activity.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Leucine-rich repeat serine/threonine-protein kinase 2, Escape Bio, Affinity

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2, Uniprot Q5S007
BindingDB Entry 50020341: Regulation of Eukaryotic Translation Initiation Factor 4E as a Potential Anticancer Strategy.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Serine/threonine-protein kinase mTOR, Qingdao University of Science and Technology, Affinity

description: Small molecule binding data for protein Serine/threonine-protein kinase mTOR, Uniprot P42345
BindingDB Entry 50020340: Discovery of
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Acetyl-CoA acetyltransferase, cytosolic, Acetyl-CoA acetyltransferase, mitochondrial, Acyl-CoA wax alcohol acyltransferase 1, Acyl-CoA wax alcohol acyltransferase 2, Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, Diacylglycerol O-acyltransferase 1, Diacylglycerol O-acyltransferase 2, Diacylglycerol O-acyltransferase 2-like protein 6, and Nuclear receptor subfamily 1 group I member 2, Affinity

description: Small molecule binding data for protein Acetyl-CoA acetyltransferase, cytosolic, Acetyl-CoA acetyltransferase, mitochondrial, Acyl-CoA wax alcohol acyltransferase 1, Acyl-CoA wax alcohol acyltransferase 2, Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, Diacylglycerol O-acyltransferase 1, Diacylglycerol O-acyltransferase 2, Diacylglycerol O-acyltransferase 2-like protein 6, and Nuclear receptor subfamily 1 group I member 2, Uniprot O75469, O75907, P24752, P26572, Q09327, Q10469, Q58HT5, Q6E213, Q6ZPD8, Q921V5, Q96PD7, and Q9BWD1
BindingDB Entry 50020336: Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, University of Florence, Affinity

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
BindingDB Entry 50020335: Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Dipeptidyl peptidase 2, Dipeptidyl peptidase 4, Dipeptidyl peptidase 8, Dipeptidyl peptidase 9, Glomulin, and Prolyl endopeptidase, University of Antwerp, Affinity

description: Small molecule binding data for protein Dipeptidyl peptidase 2, Dipeptidyl peptidase 4, Dipeptidyl peptidase 8, Dipeptidyl peptidase 9, Glomulin, and Prolyl endopeptidase, Uniprot P27487, P48147, Q6V1X1, Q86TI2, Q92990, and Q9UHL4
BindingDB Entry 50020334: Discovery of a non-covalent ligand for Rpn-13, a therapeutic target for hematological cancers.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Proteasomal ubiquitin receptor ADRM1, Purdue University, Affinity

description: Small molecule binding data for protein Proteasomal ubiquitin receptor ADRM1, Uniprot Q16186
Additional file 2: of Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
Creators: name: Wang, Lin
name: Xiaozhong Li
name: Louxin Zhang
name: Gao, Qiang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The hierarchical clustering of drugs in GDSC dataset based on their PubChem fingerprint descriptors. The similarity between pair fingerprint descriptors of drugs was measured by the Jaccard coefficient. The scale to the left of the dendrogram depicts the distance value (1-Jaccard coefficient) represented by the length of the dendrogram branches connecting pairs of node. The distance threshold was specified to 0.29 to group the drugs into clusters. (PDF 9 kb)
Additional file 2: of Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
Creators: name: Wang, Lin
name: Xiaozhong Li
name: Louxin Zhang
name: Gao, Qiang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: The hierarchical clustering of drugs in GDSC dataset based on their PubChem fingerprint descriptors. The similarity between pair fingerprint descriptors of drugs was measured by the Jaccard coefficient. The scale to the left of the dendrogram depicts the distance value (1-Jaccard coefficient) represented by the length of the dendrogram branches connecting pairs of node. The distance threshold was specified to 0.29 to group the drugs into clusters. (PDF 9 kb)
Leptotrombidium (Leptotrombidium) lushanense Wang
Creators: name: Nielsen, David H.
name: Robbins, Richard G.
name: Rueda, Leopoldo M.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Actinedida
Trombiculidae
Leptotrombidium
Leptotrombidium lushanense

description: Leptotrombidium (Leptotrombidium) lushanense Wang and Song, 1991:
PAL
Leptotrombidium (Leptotrombidium) lushanensis, Wang & Song 1991; Li et al. 1997
Leptotrombidium lushanense, Stekolnikov 2013 [9 group]
description: Published as part of Nielsen, David H., Robbins, Richard G. & Rueda, Leopoldo M., 2021, Annotated world checklist of the Trombiculidae and Leeuwenhoekiidae (1758 - 2021) (Acari: Trombiculoidea), with notes on nomenclature, taxonomy, and distribution, pp. 1-243 in Zootaxa 4967 (1) on page 134, DOI: 10.11646/zootaxa.4967.1.1, http://zenodo.org/record/4745510
BindingDB Entry 50020331: Truxillic acid monoamides as fatty acid binding protein 5 inhibitors.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Fatty acid-binding protein 5, Fatty acid-binding protein, brain, and Fatty acid-binding protein, heart, Stony Brook University, Affinity

description: Small molecule binding data for protein Fatty acid-binding protein 5, Fatty acid-binding protein, brain, and Fatty acid-binding protein, heart, Uniprot O15540, P05413, and Q01469
Additional file 1: of Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
Creators: name: Wang, Lin
name: Xiaozhong Li
name: Louxin Zhang
name: Gao, Qiang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Obtaining the updating formulas of U and V by alternating minimization algorithm. The derivation process of the updating formulas is described in detail. (PDF 192 kb)
BindingDB Entry 50020330: Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Elongin-C and von Hippel-Lindau disease tumor suppressor, University of Bonn, Affinity

description: Small molecule binding data for protein Elongin-C and von Hippel-Lindau disease tumor suppressor, Uniprot P40337 and Q15369
Additional file 5: Fig. S2. of Feed-additive probiotics accelerate yet antibiotics delay intestinal microbiota maturation in broiler chicken
Creators: name: Pengfei Gao
name: Ma, Chen
name: Sun, Zheng
name: Lifeng Wang
name: Huang, Shi
name: Xiaoquan Su
name: Xu, Jian
name: Heping Zhang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Relative abundance of the 16 age-discriminating bacterial genera in the intestinal microbiota at each time point in the three broiler groups. (PDF 205Â kb)
Additional file 1: of Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization
Creators: name: Wang, Lin
name: Xiaozhong Li
name: Louxin Zhang
name: Gao, Qiang
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Obtaining the updating formulas of U and V by alternating minimization algorithm. The derivation process of the updating formulas is described in detail. (PDF 192 kb)
Additional file 6: Fig. S6. of Synthetic hematocrit derived from the longitudinal relaxation of blood can lead to clinically significant errors in measurement of extracellular volume fraction in pediatric and young adult patients
Creators: name: Raucci, Frank
name: Parra, David
name: Christensen, Jason
name: Hernandez, Lazaro
name: Markham, Larry
name: Xu, Meng
name: Slaughter, James
name: Soslow, Jonathan
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology

description: Linear regression fit of measured vs synthetic ECVFree Wall for published and local models excluding CMRs without same day Hct. Slightly improved but still excellent regression fits for ECVFree Wall using the published model (A) and local model (C) when CMRs without same day Hct values available. Posiotive bias seen on Bland-Altman analysis of published model similar to that observed for the full cohort (B). Elimination of bias similar to that observed with full cohort seen on Bland-Altman analysis of local model. Dashed line in A and C represents line of identity. For Bland-Altman plots, solid line represents mean difference and dashed lines (B and D) are Âą1.96SD. (PDF 332 kb)
Additional file 5: Fig. S5. of Synthetic hematocrit derived from the longitudinal relaxation of blood can lead to clinically significant errors in measurement of extracellular volume fraction in pediatric and young adult patients
Creators: name: Raucci, Frank
name: Parra, David
name: Christensen, Jason
name: Hernandez, Lazaro
name: Markham, Larry
name: Xu, Meng
name: Slaughter, James
name: Soslow, Jonathan
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology

description: Linear regression fit of measured vs synthetic Hct for published and local models excluding CMRs without same day Hct. Slightly improved but still poor regression fits for Hct using the published model (A) and local model (C) when CMRs without same day Hct values available. Negative bias seen on Bland-Altman analysis of published model similar to that observed for the full cohort (B). Elimination of bias similar to that observed with full cohort seen on Bland-Altman analysis of local model. Dashed line in A and C represents line of identity. For Bland-Altman plots, solid line represents mean difference and dashed lines (B and D) are Âą1.96SD. (PDF 206 kb)
Additional file 3: Table S2. of Optimal esophageal balloon volume for accurate estimation of pleural pressure at end-expiration and end-inspiration: an in vitro bench experiment
Creators: name: Yang, Yan-Lin
name: He, Xuan
name: Sun, Xiu-Mei
name: Chen, Han
name: Shi, Zhong-Hua
name: Xu, Ming
name: Chen, Guang-Qiang
name: Zhou, Jian-Xin
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Minimal and maximal balloon inflating volume estimated by sigmoid fitting and by visual inspection of the intermediate linear section of the balloon pressure-volume curve during end-expiratory and end-inspiratory occlusion. Figure S4. Absolute balloon transmural pressure at minimal and maximal balloon inflating volume. (PDF 329 kb)
Investigation of Auxin and Cytokinin transport with bioluminescent Arabidopsis thaliana sensors growing in near-natural conditions
Creators: name: Karampelias, Mike
Publisher: name: Zenodo
Year: 2024
Subjects: Arabidopsis thaliana
Auxin-reporting autonomous bioluminescence
Cytokinin-reporting autonomous bioluminescence
Auxin transport
Hormone transport

description: In this poster. the auxin-reporting autonomous bioluminescent Arabidopsis plants were used to study auxin and cytokinin transport in rosettes
Additional file 1: Figure S1. of Lymphocyte count or percentage: which can better predict the prognosis of advanced cancer patients following palliative care?
Creators: name: Weiwei Zhao
name: Wang, Peng
name: Huixun Jia
name: Menglei Chen
name: Xiaoli Gu
name: Minghui Liu
name: Zhang, Zhe
name: Wenwu Cheng
name: Zhenyu Wu
Publisher: name: Figshare
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Flow chart of patients excluded from the study. (DOCX 28Â kb)
Additional file 1: Figure S1. of Lymphocyte count or percentage: which can better predict the prognosis of advanced cancer patients following palliative care?
Creators: name: Weiwei Zhao
name: Wang, Peng
name: Huixun Jia
name: Menglei Chen
name: Xiaoli Gu
name: Minghui Liu
name: Zhang, Zhe
name: Wenwu Cheng
name: Zhenyu Wu
Publisher: name: Figshare
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Flow chart of patients excluded from the study. (DOCX 28Â kb)
Additional file 3: of Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis
Creators: name: Xinyu Zhang
name: Donnan, Peter
name: Bell, Samira
name: Guthrie, Bruce
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Detailed reasons for excluding full text. Detailed reasons for 20 excluded papers at full text papers reviewing stage with reference. (DOCX 26Â kb)
Additional file 2: of Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis
Creators: name: Xinyu Zhang
name: Donnan, Peter
name: Bell, Samira
name: Guthrie, Bruce
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: MOOSE Checklist. Essential items to report in meta-analysis of observational studies in epidemiology. (DOCX 26Â kb)
Additional file 1: of Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis
Creators: name: Xinyu Zhang
name: Donnan, Peter
name: Bell, Samira
name: Guthrie, Bruce
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy

description: Complete search strategy. The complete search strategy for the systematic review for both Medline and Embase. (DOCX 22Â kb)
BindingDB Entry 50020328: Structure-Based Drug Design of Novel Triaminotriazine Derivatives as Orally Bioavailable IDH2
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Isocitrate dehydrogenase [NADP], mitochondrial, Nanjing University of Chinese Medicine, Affinity

description: Small molecule binding data for protein Isocitrate dehydrogenase [NADP], mitochondrial, Uniprot P48735
BindingDB Entry 50020327: Rational Design of Sulfonyl-γ-AApeptides as Highly Potent HIV-1 Fusion Inhibitors with Broad-Spectrum Activity.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Envelope glycoprotein gp160, University of South Florida, Affinity

description: Small molecule binding data for protein Envelope glycoprotein gp160, Uniprot Q72502
Additional file 7: Figure S6. of
                     Anopheles gambiae larvae mount stronger immune responses against bacterial infection than adults: evidence of adaptive decoupling in mosquitoes
Creators: name: League, Garrett
name: Estévez-Lao, Tania
name: Yan, Yan
name: Garcia-Lopez, Valeria
name: Hillyer, Julián
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Relative expression of signal modulation, immune effector, ecdysteroid biosynthesis, and ribosomal genes. Graphs show the average mRNA fold change of signal modulation (a), immune effector (b), ecdysteroid biosynthesis (c) and ribosomal (d) genes in naïve, injured, and E. coli-infected larvae, 1-day-old adults, and 5-day-old adults at 24 h post-treatment relative to the naïve group of a given life stage or adult age. Whiskers denote the SEM. Asterisks denote the significant regulation of mRNA levels relative to the naïve group as determined by the Kruskal-Wallis test, followed by Dunn’s post-hoc test (*P
BindingDB Entry 50020326: Design, Synthesis, and Activity Evaluation of Novel Dual-Target Inhibitors with Antifungal and Immunoregulatory Properties.
Creators: name: BindingDB
Publisher: name: BindingDB
Year: 2024
Subjects: Lanosterol 14-alpha demethylase, Platelet-derived growth factor receptor alpha/beta, and Programmed cell death 1 ligand 1, Liaocheng University, Affinity

description: Small molecule binding data for protein Lanosterol 14-alpha demethylase, Platelet-derived growth factor receptor alpha/beta, and Programmed cell death 1 ligand 1, Uniprot P05622, P10613, P26618, and Q9NZQ7