cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
НАЧАЛО СТАНОВЛЕНИЯ ОТЕЧЕСТВЕННОГО АНТИКОВЕДЕНИЯ В КОНТЕКСТЕ ПРОСВЕЩЕНЧЕСКОЙ И ПЕРЕВОДЧЕСКОЙ ДЕЯТЕЛЬНОСТИ: XVIII ВЕК – ОТ ПЕТРА I ДО ЕКАТЕРИНЫ II
Creators: name: Л. В. Александрова
Publisher: name: Вестник музыкальной науки
Year: 2019
Subjects: античность
антиковедение
переводческая и образовательная деятельность
преобразования Петра I
просвещение
Академия наук
историография
филология
Кантемир
Тредиаковский
Ломоносов.

description: Данная статья – третья из цикла «Из истории отечественного антиковедения» – охватывает эпоху раннего Просвещения в России, которая ограничена преобразовательной деятельностью Петра I и правлением Елизаветы Петровны. Целью данной статьи является стремление показать первые шаги антиковедения в контексте переводческой деятельности и осветить вопросы изучения древних языков в образовательном процессе. Петровским преобразованиям («европеизации») подверглись не только все государственные структуры, но и Православная церковь, в которой прежде концентрировались все образовательные процессы. В «Духовном Регламенте» – законодательном акте, определявшем правовой статус церкви в России – были определены все ступени религиозного поведения, обучения и воспитания. В области изучения языков в Академии, семинариях, а также гимназиях, университетах преимущество отдавалось латинскому языку. Важнейшим достижением XVIII в. являлось формирование письменного литературного языка, что напрямую связано с орфографией, в которой отсутствовали единые нормы правописания. Одновременно с развитием грамматики, литературного языка, совершенствованием искусства перевода появился его совершено новый вид – перевод стихотворный А. Кантемира, «зачинателя русского литературного классицизма», в новой манере – силлабике. В.К. Тредиаковский предпринял реформу русского стихосложения, разработал силлабо-тоническое стихосложение. Он первый выполнил перевод французского романа не на общепринятый тогда в литературе церковно-славянский язык, а на русский разговорный. Первые исследовательские работы по классической древности, обозначившие начало становления отечественного антиковедения, принадлежат Тредиаковскому. Продолжал совершенствовать систему стихосложения М.В. Ломоносов. Исходя из особенностей русского языка, он расширил возможности использования классических поэтических размеров, в том числе традиционного античного гекзаметра. Главным сочинением Ломоносова по русскому языку была «Российская грамматика» (1757 г.). Важнейшим достижением эпохи Просвещения был научный подход к изучению истории, филологии, естествознания и других наук, который осуществлялся со времени учреждения в Санкт-Петербурге Академии наук в 1724 г. В ней был образован «центр» профессиональных переводчиков («Российское собрание», 1735–1743 гг., затем «Историческое собрание» с 1748 г.). Работа Тредиаковского и Ломоносова, переводчиков-ученых, возвела перевод в ранг, нацеленный на решение научных, художественных, культурных проблем.
Association of nestin with anti-apoptotic and tumor suppressor factors in human breast cancer
Creators: name: Piras, Franca
name: Lai, Simone
name: Perra, Maria Teresa
name: Ionta, Maria Teresa
name: Minerba, Luigi
name: Atzori, Francesco
name: Mura, Ester
name: Maxia, Cristina
name: Murtas, Daniela
name: Demurtas, Paolo
name: Massidda, Bruno
name: Sirigu, Paola
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: breast cancer; nestin; survivin; p53; Ki-67

description: Human breast carcinoma is a heterogeneous disease embracing different phenotypes with different biological characteristics. Transcriptional profiling has identified five breast cancer subtypes, of which the “basal epithelial” is the most aggressive, with a predilection for younger women, and correlates with poor prognosis. Nestin, an intermediate filament protein, was originally identified as a marker of neuroepithelial stem/progenitor cells in the brain. Recently, it was observed that nestin is expressed in basal/myoepithelial cells of the normal mammary gland and was also later found in cancer stem like cells of many tumors. Some studies showed that nestin is robustly immunohistochemically expressed in basal epithelial and triple negative breast tumors and that its expression correlates with survival patients. The increased expression of survivin, a member of the inhibitor-of-apoptosis (IAP) protein family, has been demonstrated to be associated with resistance to apoptosis. It has been reported that survivin and other IAP proteins cooperate to activate kinase cascades that control cell motility, thus stimulating tumour cell invasion and promoting metastasis. This mechanism seems to play a central role in breast cancer progression and resistance to treatment. The p53 protein represents the final effector of the p14CDKN2AMDM2 pathway; in majority of human cancers, the TP53 gene is functionally inactivated. Lack or reduced expression levels of the p53 protein seem to be associated with a defective apoptotic response to genotoxic damage and, thus, to anticancer agents. In this study, we evaluated the immunohistochemical expression of nestin in association with an anti-apoptotic protein, such as survivin, and a tumor suppressor factor, such as p53, and with Ki-67 proliferation index in bioptic samples of T4 breast tumors. The results will be discussed.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Exploring X-ray variability with unsupervised machine learning I. Self-organizing maps applied to XMM-Newton data
Creators: name: Kovačević, Miloš
name: Pasquato, Mario
name: Marelli, Martino
name: De Luca, Andrea
name: Salvaterra, Ruben
name: Mondoni, Andrea Belfiore
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: XMM-Newton provides unprecedented insight into the X-ray Universe, recording variability information for hundreds of thousands of sources. Manually searching for interesting patterns in light curves is impractical, requiring an automated data-mining approach for the characterization of sources. Straightforward fitting of temporal models to light curves is not a sure way to identify them, especially with noisy data. We used unsupervised machine learning to distill a large data set of light-curve parameters, revealing its clustering structure in preparation for anomaly detection and subsequent searches for specific source behaviors (e.g., flares, eclipses). Self-organizing maps (SOMs) achieve dimensionality reduction and clustering within a single framework. They are a type of artificial neural network trained to approximate the data with a two-dimensional grid of discrete interconnected units, which can later be visualized on the plane. We trained our SOM on temporal-only parameters computed from more than 100,000 detections from the EXTraS catalog. The resulting map reveals that about 2500 most variable sources are clustered based on temporal characteristics. We find distinctive regions of the SOM map associated with flares, eclipses, dips, linear light curves, and others. Each group contains sources that appear similar by eye. We single out a handful of interesting sources for further study. The condensed view of our dataset provided by SOMs allowed us to identify groups of similar sources, speeding up manual characterization by orders of magnitude. Our method also highlights problems with fitting simple temporal models to light curves and can be used to mitigate them to an extent. This will be crucial for fully exploiting the high data volume expected from upcoming X-ray surveys, and may also help with interpreting supervised classification models.
description: Accepted in Astronomy & Astrophysics (A&A). Main part: 12 pages, 12 figures, 1 video (appendix: 5 pages and 4 figures)
Additional file 2 of Identification of a prognostic cuproptosis-related signature in hepatocellular carcinoma
Creators: name: Chen, Yuqiao
name: Tang, Lu
name: Huang, Wentao
name: Abisola, Fakolade Hannah
name: Zhang, Youyu
name: Zhang, Gewen
name: Yao, Lei
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 2: Table S3. The list of primer sequences involved in qPCR.
Dynamical Mean-Field Theory within an Augmented Plane-Wave Framework: Assessing Electronic Correlations in the Iron Pnictide LaFeAsO
Creators: name: Aichhorn, Markus
name: Pourovskii, Leonid
name: Vildosola, Veronica
name: Ferrero, Michel
name: Parcollet, Olivier
name: Miyake, Takashi
name: Georges, Antoine
name: Biermann, Silke
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We present an approach that combines the local density approximation (LDA) and the dynamical mean-field theory (DMFT) in the framework of the full-potential linear augmented plane waves (FLAPW) method. Wannier-like functions for the correlated shell are constructed by projecting local orbitals onto a set of Bloch eigenstates located within a certain energy window. The screened Coulomb interaction and Hund's coupling are calculated from a first-principle constrained RPA scheme. We apply this LDA+DMFT implementation, in conjunction with continuous-time quantum Monte-Carlo, to study the electronic correlations in LaFeAsO. Our findings support the physical picture of a metal with intermediate correlations. The average value of the mass renormalization of the Fe 3d bands is about 1.6, in reasonable agreement with the picture inferred from photoemission experiments. The discrepancies between different LDA+DMFT calculations (all technically correct) which have been reported in the literature are shown to have two causes: i) the specific value of the interaction parameters used in these calculations and ii) the degree of localization of the Wannier orbitals chosen to represent the Fe 3d states, to which many-body terms are applied. The latter is a fundamental issue in the application of many-body calculations, such as DMFT, in a realistic setting. We provide strong evidence that the DMFT approximation is more accurate and more straightforward to implement when well-localized orbitals are constructed from a large energy window encompassing Fe-3d, As-4p and O-2p, and point out several difficulties associated with the use of extended Wannier functions associated with the low-energy iron bands. Some of these issues have important physical consequences, regarding in particular the sensitivity to the Hund's coupling.
description: 16 pages, 9 figures, published version
title: ÐÐ»Ð¸ÑÐ½Ð¸Ðµ ÐºÐ¾ÑÐ¾Ð½Ð°Ð²Ð¸ÑÑÑÐ½Ð¾Ð¹ Ð¿Ð°Ð½Ð´ÐµÐ¼Ð¸Ð¸ Ð½Ð° Ð¾Ð±ÑÑÐµÐ½Ð¸Ðµ Ð¸Ð½Ð¾ÑÑÑÐ°Ð½Ð½Ð¾Ð¼Ñ ÑÐ·ÑÐºÑ Ð² Ð²ÑÐ·Ðµ
title: The impact of coronavirus on the foreign language teaching
Creators: name: ÐÐµÑÑÐ¼ÐµÐ»ÑÑÐµÐ²Ð°, ÐÐ»ÐµÐ½Ð°
name: ÐÑÐ¸Ð´Ð¾ÑÐ¾Ð³Ð¸Ð½Ð°, ÐÐ»ÐµÐ½Ð°
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2020
Subjects: ÐÐ½ÑÐµÑÐ½ÐµÑ
Ð½ÐµÐ¼ÐµÑÐºÐ¸Ð¹ ÑÐ·ÑÐº
Ð¾Ð½Ð»Ð°Ð¹Ð½-Ð¾Ð±ÑÑÐµÐ½Ð¸Ðµ
Ð¿Ð°Ð½Ð´ÐµÐ¼Ð¸Ñ ÐºÐ¾ÑÐ¾Ð½Ð°Ð²Ð¸ÑÑÑÐ°

description: Ð ÑÑÐ°ÑÑÐµ Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÑÑÑÑÑ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ, Ð¿ÑÐ¾Ð¸Ð·Ð¾ÑÐµÐ´ÑÐ¸Ðµ Ð² Ð¿ÑÐ¾ÑÐµÑÑÐµ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð¸Ð½Ð¾ÑÑÑÐ°Ð½Ð½Ð¾Ð¼Ñ ÑÐ·ÑÐºÑ Ð² Ð²ÑÐ·Ðµ Ð² ÑÐ²ÑÐ·Ð¸ Ñ ÐºÐ¾ÑÐ¾Ð½Ð°Ð²Ð¸ÑÑÑÐ½Ð¾Ð¹ Ð¿Ð°Ð½Ð´ÐµÐ¼Ð¸ÐµÐ¹. ÐÐ¾Ð´ÑÐµÑÐºÐ¸Ð²Ð°ÐµÑÑÑ, ÑÑÐ¾, Ð½ÐµÑÐ¼Ð¾ÑÑÑ Ð½Ð° ÑÑÐ´ ÑÐ»Ð¾Ð¶Ð½Ð¾ÑÑÐµÐ¹, Ð²ÑÐ½ÑÐ¶Ð´ÐµÐ½Ð½ÑÐ¹ Ð¿ÐµÑÐµÑÐ¾Ð´ Ð½Ð° Ð¾Ð½Ð»Ð°Ð¹Ð½-ÑÐ¾ÑÐ¼Ð°Ñ, Ð¸Ð¼ÐµÐ» ÑÐ°ÐºÐ¶Ðµ ÑÐ²Ð¾Ð¸ Ð¿Ð»ÑÑÑ, ÐºÐ°Ðº Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², ÑÐ°Ðº Ð¸ Ð´Ð»Ñ Ð¿ÑÐµÐ¿Ð¾Ð´Ð°Ð²Ð°ÑÐµÐ»ÐµÐ¹. ÐÑÐ´ÐµÐ»ÑÑÑÑÑ Ð¸ Ð¾Ð¿Ð¸ÑÑÐ²Ð°ÑÑÑÑ 3 ÑÑÐ¾Ð²Ð½Ñ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ð¹ ÑÑÐµÐ±Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÑÐµÑÑÐ°: Ð»ÐµÐºÑÐ¸ÑÐµÑÐºÐ¸Ð¹, ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð¸ Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¸Ð¹.
description: The article explores the changes in teaching a foreign language (German) at a college level during the COVID-19 pandemic. The forced shift to the online education was difficult, but it had also some positive changes for both teachers and students. The article anlyses 3 aspects of changes in teaching a foreighn language: linguistic, topical and medothical.
Evaluating Touch-Table Technology in Neighbourhood Planning
Creators: name: Lay, Erica
Publisher: name: The University of British Columbia
Year: 2013

description: The International Panel for Climate Change’s Fourth Assessment Report (2007), drawing on the work of scientists and climate change experts worldwide, reports that not only can we observe altered climate scenarios across the globe, but that we can attribute these changes to greenhouse gas (GHG) emission levels that are generated by humans and that are higher than normal. The depth of GHG emission reduction needed to reverse climate change must be driven by national and international agreements and initiatives. However, research shows that individual citizens are more compelled to act on climate change initiatives when climate change communication is made tangible and local (Nicholson-Cole 2005; Moser 2010). One of the ways we can do this is to engage people using local government’s most significant public policy tool to address climate change: land-use planning (Andrews 2008: 847). Planning professionals and teams are increasingly using visual technology in planning processes to attract more participants, to convey information on complex issues, and to directly involve citizens in neighbourhood planning, with the intent of empowering citizens in the decision-making processes. Visual technology tools offer promise for helping to articulate more explicit links between urban form (neighbourhood design) and climate change by making information tangible to local users (Robinson in Campbell 2006; Senbel and Church 2011; Sheppard et al. 2011). Using a case-study in Revelstoke, BC, this paper examines how one of these tools can serve to go beyond engagement to mediate instances of empowerment. A team of University of British Columbia (UBC) researchers is in the research and development stage of creating a computer user-interface that enables users to collaboratively design and visualize future neighbourhoods, in both 2- and 3-D, by means of a touch-sensitive table-like computer screen. Over the course of 24 workshops (two separate weeks) in Revelstoke, 48 participants were engaged using this ‘touch-table’ to plan one of two future neighbourhood centres in their hometown. Examining the video and audio transcripts of these workshops with Senbel and Church’s 6-I's of Design Empowerment, results showed that the touch-table augments participatory processes by supporting procedural and substantive learning, information, ideation, and integration in neighbourhood design. The tool showed potential but not direct evidence of integration, inclusion and independence. Recommendations for future use of the touch-table include considering
title: ÐÑÐ±Ð¾Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ¸Ð¸ Ð¸ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾ Ð½Ð° ÑÐ°Ð±Ð¾ÑÑ
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð¿Ð¾ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð² ÑÑÑÐ½Ð¾Ð¹ Ð¸ Ð¿Ð¸ÑÑÐ¼ÐµÐ½Ð½Ð¾Ð¹ ÑÐµÑÐ¸ Ð½Ð° Ð½ÐµÐ¼ÐµÑÐºÐ¾Ð¼ ÑÐ·ÑÐºÐµ
titleType: Subtitle
Creators: name: ÐÐ¾Ð³Ð´Ð°Ð½Ð¾Ð²Ð°, ÐÐ°Ð´ÐµÐ¶Ð´Ð°
name: ÐÑÑÑÐ¸Ð½Ð°, Ð¡Ð²ÐµÑÐ»Ð°Ð½Ð°
Publisher: name: Ð¡ÐÐ±ÐÐ¢Ð£
Year: 1995
Subjects: Ð½ÐµÐ¼ÐµÑÐºÐ¸Ð¹ ÑÐ·ÑÐº
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: ÐÐºÐ»ÑÑÐµÐ½Ñ ÑÐµÐºÑÑÑ Ð² Ð¾ÑÐ½Ð¾Ð²Ð½Ð¾Ð¼ Ð¸Ð· Ð¾ÑÐ¸Ð³Ð¸Ð½Ð°Ð»ÑÐ½ÑÑ Ð¸ÑÑÐ¾ÑÐ½Ð¸ÐºÐ¾Ð² Ð´Ð»Ñ Ð¸Ð·ÑÑÐ°ÑÑÐµÐ³Ð¾ Ð¸ Ð¾Ð·Ð½Ð°ÐºÐ¾Ð¼Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ ÑÑÐµÐ½Ð¸Ñ Ð¸ ÑÐ¿ÑÐ°Ð¶Ð½ÐµÐ½Ð¸Ñ Ð´Ð»Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð² ÑÑÑÐ½Ð¾Ð¹ Ð¸ Ð¿Ð¸ÑÑÐ¼ÐµÐ½Ð½Ð¾Ð¹ ÑÐµÑÐ¸. ÐÐ°Ð´Ð°Ð½Ð¸Ñ Ð¼Ð¾Ð³ÑÑ Ð±ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ñ Ð² Ð°ÑÐ´Ð¸ÑÐ¾ÑÐ½Ð¾Ð¹ Ð¸ ÑÐ°Ð¼Ð¾ÑÑÐ¾ÑÑÐµÐ»ÑÐ½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ. Ð ÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð¾Ð²Ð°Ð½Ñ ÐºÐ°ÑÐµÐ´ÑÐ¾Ð¹ Ð¸Ð½Ð¾ÑÑÑÐ°Ð½Ð½ÑÑ ÑÐ·ÑÐºÐ¾Ð² Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¾Ð³Ð¾ ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ° Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² 2-Ð³Ð¾ Ð¸ 3-Ð³Ð¾ ÐºÑÑÑÐ¾Ð² ÑÐ°ÐºÑÐ»ÑÑÐµÑÐ° ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ¸ Ð¸ Ð¼ÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½ÑÐ°.
description: ÐÐµÑÐ°ÑÐ°ÐµÑÑÑ Ð¿Ð¾ ÑÐµÑÐµÐ½Ð¸Ñ ÑÐµÐ´Ð°ÐºÑÐ¸Ð¾Ð½Ð½Ð¾-Ð¸Ð·Ð´Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ ÑÐ¾Ð²ÐµÑÐ° Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ°.
Adhesion of Multi-component Vesicle Membranes
Creators: name: Zhao, Yanxiang
name: Das, Sovan
name: Du, Qiang
Publisher: name: arXiv
Year: 2009
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: In this work, we study the adhesion of multi-component vesicle membrane to both flat and curved substrates, based on the conventional Helfrich bending energy for multi-component vesicles and adhesion potentials of different forms. A phase field formulation is used to describe the different components of the vesicle. For the axisymmetric case, a number of representative equilibrium vesicle shapes are computed and some energy diagrams are presented which reveal the dependence of the calculated shapes and solution branches on various parameters including both bending moduli and spontaneous curvatures as well as the adhesion potential constants. Our computation also confirms a recent experimental observation that the adhesion effect may promote phase separation in two-component vesicle membranes.
description: 10 pages, 11 figures
PKCε expression is required during proplatelet formation in murine model
Creators: name: Gobbi, Giuliana
name: Carubbi, Cecilia
name: Galli, Daniela
name: Di Marcantonio, Daniela
name: Bucci, Giovanna
name: Masselli, Elena
name: Queirolo, Valeria
name: Mirandola, Prisco
name: Vaccarezza, Mauro
name: Italiano, Joseph E.
name: Vitale, Marco
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Megakaryocytopoyesis; PKCepsilon; proplatelet formation

description: Megakaryocytes (MK) remodel their cytoplasm into long proplatelet extensions to generate platelets [1]. We have previously demonstrated that PKCepsilon expression is strictly regulated during megakaryocytopoiesis (MKpoiesis), and its forced expression in the late phases of MK differentiation impairs platelet production [2,3]. However, our preliminary data suggest that PKCepsilon positive platelets may be released around the acute event of myocardial infarction, affecting their aggregation potential. Primary fetal liver (FL) cells isolated from CD1 pregnant mice are the preferential model to study the platelet formation mechanism [4]. Therefore, here we focused on the mouse PKCepsilon positive model to elucidate the role of PKCepsilon in MK maturation. Our data show that not only PKCepsilon expression increases during mouse MK differentiation, but also its forced down-regulation strongly reduces pro-platelet formation. Therefore, PKCepsilon is strongly required for murine proplatelet production. On the basis of these results and other known model systems, we show that PKCepsilon has a relevant role in the completion of platelet release.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
Electron spins interaction in the spin-Peierls phase of the organic spin chain (o -DMTTF) 2 X (X = Cl, Br, I)
Creators: name: Soriano, Loic
name: Pilone, Olivier
name: Kuz'Min, Michael D.
name: Vezin, Herve
name: Jeannin, Olivier
name: Fourmigué, Marc
name: Orio, Maylis
name: Bertaina, Sylvain
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the electron spin resonance of the organic spin-Peierls chain (o-DMTTF)2X with X = Cl, Br and I. We describe the temperature dependence of the spin gap during the phase transition and quantify the dimerization parameter $δ$. At the lowest temperatures, the susceptibility is governed by defects in the spin dimerized chain. Such strongly correlated defects are the consequence of breaks in the translational symmetry of the chain. In the vicinity of the defects the spins are polarized antiferomagnetically forming a magnetic soliton: a spin 1 2 quasi-particle of size ruled by $δ$ pinned to the defects. For (o-DMTTF)2Br and (o-DMTTF)2Cl, we show that the one-half of the total number of solitons are in isolation (as singles) whereas the other half form pairs (soliton dimers)with a strong magnetic coupling. The Rabi oscillations of both the single-soliton and the soliton-dimer are observed, which is a prerequisite in the context of quantum information.
Pamela, FGST and Sub-Tev Dark Matter
Creators: name: Hooper, Dan
name: Zurek, Kathryn M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: PAMELA's observation that the cosmic ray positron fraction increases rapidly with energy implies the presence of primary sources of energetic electron-positron pairs. Of particular interest is the possibility that dark matter annihilations in the halo of the Milky Way provide this anomalous flux of antimatter. The recent measurement of the cosmic ray electron spectrum by the Fermi Gamma Ray Space Telescope, however, can be used to constrain the nature of any such dark matter particle. In particular, it has been argued that in order to accommodate the observations of Fermi and provide the PAMELA positron excess, annihilating dark matter particles must be as massive as ~1 TeV or heavier. In this article, we revisit Fermi's electron spectrum measurement within the context of annihilating dark matter, focusing on masses in the range of 100-1000 GeV, and considering effects such as variations in the astrophysical backgrounds from the presence of local cosmic ray accelerators, and the finite energy resolution of the Fermi Gamma Ray Space Telescope. When these factors are taken into account, we find that dark matter particles as light as ~300 GeV can be capable of generating the positron fraction observed by PAMELA.
description: 16 pages, 10 figures
Weight Optimization for Consensus Algorithms with Correlated Switching Topology
Creators: name: Jakovetic, Dusan
name: Xavier, Joao
name: Moura, Jose M. F.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We design the weights in consensus algorithms with spatially correlated random topologies. These arise with: 1) networks with spatially correlated random link failures and 2) networks with randomized averaging protocols. We show that the weight optimization problem is convex for both symmetric and asymmetric random graphs. With symmetric random networks, we choose the consensus mean squared error (MSE) convergence rate as optimization criterion and explicitly express this rate as a function of the link formation probabilities, the link formation spatial correlations, and the consensus weights. We prove that the MSE convergence rate is a convex, nonsmooth function of the weights, enabling global optimization of the weights for arbitrary link formation probabilities and link correlation structures. We extend our results to the case of asymmetric random links. We adopt as optimization criterion the mean squared deviation (MSdev) of the nodes states from the current average state. We prove that MSdev is a convex function of the weights. Simulations show that significant performance gain is achieved with our weight design method when compared with methods available in the literature.
description: 30 pages, 5 figures, submitted to IEEE Transactions On Signal Processing
The Rotation of Magnetic Flux Rope Formed during Solar Eruption
Creators: name: Zhou, Zhenjun
name: Jiang, Chaowei
name: Liu, Rui
name: Wang, Yuming
name: Liu, Lijuan
name: Cui, Jun
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: The eruptions of solar filaments often show rotational motion about their rising direction, but it remains elusive what mechanism governs such rotation and how the rotation is related to the initial morphology of the pre-eruptive filament (and co-spatial sigmoid), filament chirality, and magnetic helicity. The conventional view regarding the rotation as a result of a magnetic flux rope (MFR) under-going the ideal kink instability still has confusion in explaining these relationships. Here we proposed an alternative explanation for the rotation during eruptions, by analyzing a magnetohydrodynamic simulation in which magnetic reconnection initiates an eruption from a sheared arcade configuration and an MFR is formed during eruption through the reconnection. The simulation reproduces a reverse S-shaped MFR with dextral chirality, and the axis of this MFR rotates counterclockwise while rising, which compares favorably with a typical filament eruption observed from dual viewing angles. By calculating the twist and writhe numbers of the modeled MFR during its eruption, we found that accompanied with the rotation, the nonlocal writhe of the MFR's axis decreases while the twist of its surrounding field lines increases, and this is distinct from the kink instability, which converts magnetic twist into writhe of the MFR axis.
From research to sports practice, reliably measuring wheelchair mobility performance in it simpelest form.
Creators: name: Van der Slikke, Rienk
name: van Dilgt, Melle
name: Keijsers, Thomas
name: Berger, Monique
Publisher: name: Loughborough University
Year: 2024

description: Engineering of Sport 15 - Proceedings from the 15th International Conference on the Engineering of Sport (ISEA 2024)
Wheelchair Mobility Performance (WMP) measures are becoming increasingly important in wheelchair court sports practice.  In this study, the improved AHRS algorithm is used for estimating wheelchair frame rotational speed based on a wheel sensor, to compare those data with the directly measured frame rotational speed, during match play at the highest level of wheelchair tennis.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð»Ñ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ñ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸ Ð¸ Ð°Ð²ÑÐ¾ÑÐ¸Ð·Ð°ÑÐ¸Ð¸.
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÑÐ´Ð°ÑÐµÐ², ÐÐ»Ð°Ð´Ð¸ÑÐ»Ð°Ð²
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ
Ð¼ÐµÑÐ¾Ð´Ñ Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸
Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ Ð² Ð²ÐµÐ±-Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸ÑÑ

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ ÑÐ¸ÑÑÐµÐ¼ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð´Ð¾ÑÑÑÐ¿Ð° Ð² Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼Ð°Ñ. Ð¦ÐµÐ»ÑÑ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ, Ð°Ð½Ð°Ð»Ð¸Ð· Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸, ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ, ÑÐµÐ°Ð»Ð¸Ð·ÑÑÑÐµÐ³Ð¾ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð½ÑÐµ Ð¼ÐµÑÐ¾Ð´Ñ Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð²ÑÐ±Ð¾ÑÐ° Ð¼ÐµÑÐ¾Ð´Ð° Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸. ÐÑÑÐ²Ð»ÐµÐ½Ð½ÑÐµ ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑ Ð¾Ð±ÐµÑÐ¿ÐµÑÐ¸ÑÑ Ð²ÑÐ±Ð¾Ñ Ð¼ÐµÑÐ¾Ð´Ð° Ð°ÑÑÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸ Ð´Ð»Ñ Ð´Ð¾Ð»Ð¶Ð½Ð¾Ð³Ð¾ ÑÑÐ¾Ð²Ð½Ñ Ð·Ð°ÑÐ¸ÑÑ Ð´Ð°Ð½Ð½ÑÑ Ð² Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼Ð°Ñ, Ð² ÑÐ°ÑÑÐ½Ð¾ÑÑÐ¸ Ð·Ð°ÑÐ¸ÑÑ Ð´Ð°Ð½Ð½ÑÑ Ð²ÐµÐ±-ÑÐµÑÐ²ÐµÑÐ¾Ð².
The shaping effect of collimated fast outflows in the Egg nebula
Creators: name: Dinh-V-Trung
name: Lim, Jeremy
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present high angular resolution observations of the HC$_3$N J=5--4 line from the Egg nebula, which is the archetype of protoplanetary nebulae. We find that the HC$_{\rm 3}$N emission in the approaching and receding portion of the envelope traces a clumpy hollow shell, similar to that seen in normal carbon rich envelopes. Near the systemic velocity, the hollow shell is fragmented into several large blobs or arcs with missing portions correspond spatially to locations of previously reported high--velocity outlows in the Egg nebula. This provides direct evidence for the disruption of the slowly--expanding envelope ejected during the AGB phase by the collimated fast outflows initiated during the transition to the protoplanetary nebula phase. We also find that the intersection of fast molecular outflows previously suggested as the location of the central post-AGB star is significantly offset from the center of the hollow shell. From modelling the HC$_3$N distribution we could reproduce qualitatively the spatial kinematics of the HC$_3$N J=5--4 emission using a HC$_3$N shell with two pairs of cavities cleared by the collimated high velocity outflows along the polar direction and in the equatorial plane. We infer a relatively high abundance of HC$_3$N/H$_2$ $\sim$3x10$^{-6}$ for an estimated mass--loss rate of 3x10$^{-5}$ M$_\odot$ yr$^{-1}$ in the HC$_3$N shell. The high abundance of HC$_3$N and the presence of some weaker J=5--4 emission in the vicinity of the central post-AGB star suggest an unusually efficient formation of this molecule in the Egg nebula.
description: 22 pages, 6 figures, submitted to the Astrophysical Journal
Experimental investigation of hybrid single-electron turnstiles with high charging energy
Creators: name: Kemppinen, A.
name: Kafanov, S.
name: Pashkin, Yu. A.
name: Tsai, J. S.
name: Averin, D. V.
name: Pekola, J. P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present an experimental study of hybrid turnstiles with high charging energies in comparison to the superconducting gap. The device is modeled with the sequential tunneling approximation. The backtunneling effect is shown to limit the amplitude of the gate drive and thereby the maximum pumped current of the turnstile. We compare results obtained with sine and square wave drive and show how a fast rise time can suppress errors due to leakage current. Quantized current plateaus up to 160 pA are demonstrated.
description: 4 pages, 3 figures
title: ÐÐ½ÑÑÐ¸ÑÑÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð°Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ°. Ð§. 1
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ¸ÑÐ¸Ð³Ð¸Ð½, ÐÐ»ÐµÐ³
name: ÐÐµÐ³ÑÑÑÐµÐ²Ð°, ÐÐ¸ÐºÑÐ¾ÑÐ¸Ñ
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2018
Subjects: Ð¸Ð½ÑÑÐ¸ÑÑÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð°Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ°
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: Ð¡Ð¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÐµÑ Ð¤ÐÐÐ¡ ÐÐ ÑÑÐµÑÑÐµÐ³Ð¾ Ð¿Ð¾ÐºÐ¾Ð»ÐµÐ½Ð¸Ñ Ð¸ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÐ¼ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸ÑÐ¼ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ ÐºÐ°Ð´ÑÐ¾Ð².
Ð ÑÑÐµÐ±Ð½Ð¾Ð¼ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð° ÑÑÑÐ½Ð¾ÑÑÑ Ð¸Ð½ÑÑÐ¸ÑÑÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð¹ ÑÐµÐ¾ÑÐ¸Ð¸, Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ñ Ð±Ð°Ð·Ð¾Ð²ÑÐµ Ð¿Ð¾Ð½ÑÑÐ¸Ñ ÑÐµÐ¾ÑÐ¸Ð¸ ÑÑÐ°Ð½ÑÐ°ÐºÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¸Ð·Ð´ÐµÑÐ¶ÐµÐº, ÑÐµÐ¾ÑÐ¸Ð¸ Ð¿ÑÐ°Ð² ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½Ð¾ÑÑÐ¸, ÑÐµÐ¾ÑÐ¸Ð¸ ÐºÐ¾Ð½ÑÑÐ°ÐºÑÐ½ÑÑ Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ð¹. ÐÐ·Ð»Ð¾Ð¶ÐµÐ½Ñ Ð¸Ð½ÑÑÐ¸ÑÑÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÐµ Ð¾ÑÐ½Ð¾Ð²Ñ ÑÐµÐ¾ÑÐ¸Ð¸ ÑÐ¸ÑÐ¼Ñ Ð¸ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²Ð°. ÐÐ°Ð¶Ð´Ð°Ñ ÑÐµÐ¼Ð° ÑÐ¾Ð´ÐµÑÐ¶Ð¸Ñ ÐºÐ¾Ð½ÑÑÐ¾Ð»ÑÐ½ÑÐµ Ð²Ð¾Ð¿ÑÐ¾ÑÑ Ð´Ð»Ñ ÑÐ°Ð¼Ð¾Ð¿ÑÐ¾Ð²ÐµÑÐºÐ¸.
ÐÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² Ð²ÑÐµÑ ÑÐ¾ÑÐ¼ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÐ¼ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Â«ÐÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½ÑÂ» (Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ¸Ð°Ñ) Ð¸ Â«Ð­ÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ°Â» (Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ¸Ð°Ñ),
Ð° ÑÐ°ÐºÐ¶Ðµ Ð´Ð»Ñ Ð¿ÑÐµÐ¿Ð¾Ð´Ð°Ð²Ð°ÑÐµÐ»ÐµÐ¹ Ð¸ Ð½Ð°ÑÑÐ½ÑÑ ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ¾Ð², Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ñ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÐµÐ¾ÑÐ¸Ð¸ Ð¸ Ð¸Ð½ÑÑÐ¸ÑÑÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð¹ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÐºÐ¸.
Collective Helping and Bystander Effects in Coevolving Helping Networks
Creators: name: Jo, Hang-Hyun
name: Lee, Hyun Keun
name: Park, Hyunggyu
Publisher: name: arXiv
Year: 2010
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study collective helping behavior and bystander effects in a coevolving helping network model. A node and a link of the network represents an agent who renders or receives help and a friendly relation between agents, respectively. A helping trial of an agent depends on relations with other involved agents and its result (success or failure) updates the relation between the helper and the recipient. We study the network link dynamics and its steady states analytically and numerically. The full phase diagram is presented with various kinds of active and inactive phases and the nature of phase transitions are explored. We find various interesting bystander effects, consistent with the field study results, of which the underlying mechanism is proposed.
МОДЕСТ МУСОРГСКИЙ, УКАЗЫВАЮЩИЙ ПУТЬ В XX ВЕК (ПЕРЕВОД, ПОДГОТОВКА К ПЕЧАТИ А. А. МАЛЬЦЕВОЙ)
Creators: name: БЮЗИНГ ОТФРИД
Publisher: name: Вестник музыкальной науки
Year: 2019
Subjects: МОДЕСТ МУСОРГСКИЙ
ЗВУК
«НОЧЬ НА ЛЫСОЙ ГОРЕ»
«БОРИС ГОДУНОВ»
«КАРТИНКИ С ВЫСТАВКИ»
XX И XXI В
MODEST MUSORGSKIJ
SOUND
“A NIGHT ON BARE MOUNTAIN”
“BORIS GODUNOV”
“PICTURES AT AN EXHIBITION”
THE 20TH AND 21ST CENTURIES

description: Как известно, музыка XX и XXI в. характеризуется плюрализмом. Его многочисленные пути развития в значительной степени связаны с ситуациями потрясений и обновлений, которые происходили в период до 1900 г. Среди композиторов, которые дали импульс последующим преобразованиям, -Клод Дебюсси, Эрик Сати, Александр Скрябин, Чарльз Айвс, Арнольд Шенберг и Игорь Стравинский, но самым ранним из них был Модест Мусоргский, чьи новаторские заслуги часто принимаются не более чем как что-то само собой разумеющееся. В своих произведениях Ночь на Лысой горе (1867), Борис Годунов (первая версия 1869) и Картинки с выставки (1874) Мусоргский на довольно раннем этапе истории музыки совершил последовательные новаторства в искусстве композиции, включая две категории, ведущие в будущее: сосредоточение внимания на отдельно взятой категории звук (например, Ночь [на Лысой горе], Борис [Годунов], Картинки [с выставки]) и отклонения от идей, считавшихся абсолютно неприкосновенными с XV в., таких как отход от использования самостоятельных [мелодических] линий (Realstimmigkeit) путем применения параллельных октав и квинт и / или широкое использование парафонии, как, например, в «Прогулке», «Балете невылупившихся птенцов» и «Гноме» из Картинок с выставки. В этих произведениях Мусоргский породил события, которые затем имели долгую последующую историю.
Morphological analysis of the acute effects of cigarette smoke on normal human oral mucosa explants
Creators: name: Gualerzi, Alice
name: Cornaghi, Laura
name: Sciarabba, Michele
name: Donetti, Elena
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Cigarette smoke; epithelial differentiation markers

description: Cigarette smoke is one of the five leading risk factors for mortality in the world and smoking related lung cancer is the main cause of deaths from cancer in both sexes in the United States. This habit is particularly popular in Western low- and middle- income countries, with about one billion males and 250 million females smoking in the world. Human oral mucosa is the combustion chamber of cigarette, but scanty evidence is available about the early smoke effects. The present work aimed at evaluating from a morphological point of view whole smoke early effects on epithelial intercellular adhesion and keratinocyte terminal differentiation in a three-dimensional model of human oral mucosa. Biopsies of keratinized oral mucosa of healthy non smoking women (n = 5) were collected. After culturing in a Transwell system, one fragment of each biopsy was exposed to the smoke of one single cigarette; the remnant represented the internal control. The distribution of epithelial differentiation markers (keratin-10, K10, and keratin-14, K14, for suprabasal and basal cells respectively), desmosomes (desmoglein-1, desmoglein-3), tight junctions (occludin), adherens junctions (E-cadherin, β-catenin), and apoptotic cells (p53, caspase-3) were evaluated by immunofluorescence. Quantitative analysis of K14 immunolabeling revealed an over expression in the suprabasal layers as early as 3 hours after smoke exposure, without impairment of the epithelial junctional apparatus and apoptosis induction. The present study showed that the early response of the normal human oral mucosa to acute exposure to the smoke of one single cigarette induced K14 expression in suprabasal oral keratinocytes, without impairment of the epithelial junctional apparatus and apoptosis induction, suggesting that the first significant response to cigarette smoke arise from the basal and suprabasal layers of the human oral epithelium. The novelty of the present work consists in the combination of human oral explants with a non hermetic smoke exposure system. The main improvement offered by this setting is the ability of reproducing the cyclic condition by which cigarette smoke normally comes in contact with the oral mucosa. Furthermore, it allows administering simultaneously both gaseous phase and particulate matter of cigarette smoke.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
Terahertz control of photoluminescence emission in few-layer InSe
Creators: name: Venanzi, Tommaso
name: Selig, Malte
name: Pashkin, Alexej
name: Winnerl, Stephan
name: Katzer, Manuel
name: Arora, Himani
name: Erbe, Artur
name: Patanè, Amalia
name: Kudrynskyi, Zakhar R.
name: Kovalyuk, Zakhar D.
name: Baldassarre, Leonetta
name: Knorr, Andreas
name: Helm, Manfred
name: Schneider, Harald
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A promising route for the development of opto-elelctronic technology is to use terahertz radiation to modulate the optical properties of semiconductors. Here we demonstrate the dynamical control of photoluminescence (PL) emission in few-layer InSe using picosecond terahertz pulses. We observe a strong PL quenching (up to 50%) after the arrival of the terahertz pulse followed by a reversible recovery of the emission on the time scale of 50ps at T =10K. Microscopic calculations reveal that the origin of the photoluminescence quenching is the terahertz absorption by photo-excited carriers: this leads to a heating of the carriers and a broadening of their distribution, which reduces the probability of bimolecular electron-hole recombination and, therefore, the luminescence. By numerically evaluating the Boltzmann equation, we are able to clarify the individual roles of optical and acoustic phonons in the subsequent cooling process. The same PL quenchingmechanismis expected in other van derWaals semiconductors and the effectwill be particularly strong for materials with low carrier masses and long carrier relaxation time, which is the case for InSe. This work gives a solid background for the development of opto-electronic applications based on InSe, such as THz detectors and optical modulators.
description: The following article has been accepted by Applied Physics Letters. After it is published, it will be found at https://publishing.aip.org/resources/librarians/products/journals/
title: Ð¡Ð¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÐµ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¼ÐµÑ Ð°Ð½Ð¸ÐºÐ¸. ÐÐµÑ Ð°Ð½Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð° ÐºÐ¾Ð²Ð°Ð»ÐµÐ½ÑÐ½ÑÑ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð²
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð² Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð¼Ð°Ð³Ð¸ÑÑÑÐ¾Ð² "ÐÑÐ¸ÐºÐ»Ð°Ð´Ð½Ð°Ñ Ð¼ÐµÑ Ð°Ð½Ð¸ÐºÐ°"
titleType: Subtitle
Creators: name: ÐÐµÑÐ¸Ð½ÑÐºÐ¸Ð¹, ÐÐ³Ð¾ÑÑ
name: ÐÑÐ¸Ð²ÑÐ¾Ð², ÐÐ½ÑÐ¾Ð½
name: ÐÑÐ´Ð°ÑÐ¾Ð²Ð°, ÐÑÐ¸Ñ
name: ÐÑÐ·ÑÐºÐ¸Ð½, ÐÐ¸ÑÐ°Ð»Ð¸Ð¹
name: ÐÐ¾Ð±Ð¾Ð´Ð°, ÐÐ»ÑÐ³Ð°
name: Ð¥Ð°ÐºÐ°Ð»Ð¾, Ð¡ÐµÑÐ³ÐµÐ¹
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2014
Subjects: ÐÐµÑ Ð°Ð½Ð¸ÐºÐ°
ÐÑÐ¸ÑÑÐ°Ð»Ð»Ð¾ÑÐ¸Ð·Ð¸ÐºÐ°
ÐÑÐ°ÑÐµÐ½Ñ
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Differential expression of junctional adhesion molecules in different stages of systemic sclerosis: pathogenetic implications
Creators: name: Manetti, Mirko
name: Rosa, Irene
name: Guiducci, Serena
name: Milia, Anna Franca
name: Romano, Eloisa
name: Matucci-Cerinic, Marco
name: Ibba-Manneschi, Lidia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2013
Subjects: Junctional adhesion molecules; microvascular endothelial cells; skin; systemic sclerosis

description: Systemic sclerosis (SSc, scleroderma) is characterized by early perivascular inflammation, microvascular endothelial cell (MVEC) activation/damage and defective angiogenesis. Junctional adhesion molecules (JAMs) regulate leukocyte recruitment to sites of inflammation and ischemia-reperfusion injury, vascular permeability and angiogenesis. In the present study, we investigated the possible role of JAMs in SSc pathogenesis.The expression of JAM-A and JAM-C in skin biopsies from 25 patients with SSc (14 early-stage SSc, 11 late-stage SSc) and 15 healthy subjects was investigated by immunohistochemistry and western blotting. Subcellular localization of JAMs in cultured dermal healthy MVECs (H-MVECs) and early-stage SSc-MVECs was assessed by confocal laser scanning microscopy. Serum levels of soluble JAM-A (sJAM-A) and JAM-C (sJAM-C) from 64 SSc patients (25 early-stage SSc, 39 late-stage SSc) and 32 healthy subjects were examined by ELISA.In control skin, constitutive JAM-A expression was observed in dermal MVECs and fibroblasts. In early-stage SSc skin, JAM-A expression was strongly increased in MVECs, fibroblasts and perivascular infiltrating inflammatory cells. In late-stage SSc, JAM-A expression was decreased compared with healthy controls. JAM-C was weakly expressed in control and latestage SSc skin, while it was strongly expressed in MVECs, fibroblasts and inflammatory cells from early-stage SSc skin. Cell surface expression of JAM-A was higher in early-stage SSc-MVECs and increased in H-MVECs upon stimulation with early-stage SSc sera. JAM-C was cytoplasmic in resting H-MVECs, while it was rapidly recruited to the cell surface upon challenging with early-stage SSc sera. Early-stage SSc-MVECs exhibited increased expression and constitutive localization of JAM-C on the cell surface. Circulating levels of sJAM-A and sJAM-C were significantly increased in earlystage SSc compared with healthy controls and late-stage SSc. In addition, sJAM-A and sJAM-C levels were significantly raised in SSc patients with ‘early/active’ nailfold capillaroscopic pattern compared with those with ‘late’ capillaroscopic pattern. Collectively, the results of our study suggest that JAMs may participate in dermal MVEC activation, inflammatory processes and impaired angiogenesis in different stages of SSc.
description: Italian Journal of Anatomy and Embryology, Vol 117, No 2 (Supplement) 2012
Annotations in the classroom; the classroom in annotations
Creators: name: Enkhbayar, Asura
Publisher: name: Zenodo
Year: 2019
Subjects: annotations
social reading
education

description: In this talk I want to explore the impact of using Hypothesis in the classroom. What does it mean to read, think, and annotate publicly? How does it change your learning experience as a student? How do you evaluate and assess different annotation styles as a teacher? As a student I can share my own experience of this new mode of teaching and learning. As a data scientist, I want to give a taste of possible new metrics and measurements based on annotation data. Finally, as a critical scholar I am hoping to explore how this new metrification and monitoring of reading might affect education. The talk will rely on data outlined in this essay: https://course-journals.lib.sfu.ca/index.php/pdc2018/article/view/240/213