cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Long-term outcomes of over 8,000 medial Oxford Phase 3 Unicompartmental Knees—a systematic review
Creators: name: Mohammad, Hasan R
name: Strickland, Louise
name: Hamilton, Thomas W
name: Murray, David W
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Background and purpose — There is debate as to the relative merits of unicompartmental and total knee arthroplasty (UKA, TKA). Although the designer surgeons have achieved good results with the Oxford UKA there is concern over the reproducibility of these outcomes. Therefore, we evaluated published long-term outcomes of the Oxford Phase 3 UKA. Patients and methods — We searched databases to identify studies reporting ≥10 year outcomes of the medial Oxford Phase 3 UKA. Revision, non-revision, and re-operation rates were calculated per 100 component years (% pa). Results — 15 studies with 8,658 knees were included. The annual revision rate was 0.74% pa (95% CI 0.67–0.81, n = 8,406) corresponding to a 10-year survival of 93% and 15-year survival of 89%. The non-revision re-operation rate was 0.19% pa (95% CI 0.13–0.25, n = 3,482). The re-operation rate was 0.89% pa (95% CI 0.77–1.02, n = 3,482). The most common causes of revision were lateral disease progression (1.42%), aseptic loosening (1.25%), bearing dislocation (0.58%), and pain (0.57%) (n = 8,658). Average OKS scores were 40 at 10 years (n = 3,417). The incidence of medical complications was 0.83% (n = 1,443). Interpretation — Very good outcomes were achieved by both designer and non-designer surgeons. The PROMs, medical complication rate, and non-revision re-operation rate were better than those found in meta-analyses and publications for TKA but the revision rate was higher. However, if failure is considered to be all re-operations and not just revisions, then the failure rate of UKA was less than that of TKA.
Isolation, structural identification and biological characterization of two conopeptides from the Conus pennaceus venom
Creators: name: Abdel-Wahab, Mohammed
name: Miyashita, Masahiro
name: Ota, Yoshiyuki
name: Juichi, Hironori
name: Okabe, Ryota
name: Sarhan, Moustafa
name: Fouda, Maged
name: Abdel-Rahman, Mohamed
name: Saber, Samy
name: Nakagawa, Yoshiaki
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: A novel anti-mollusk conopeptide pn4c was isolated from the Conus pennaceus venom by repeated HPLC fractionation based on the activity against freshwater snails. The primary structure of pn4c was determined by the mass spectrometric de novo sequencing analysis. In addition, pn3a was isolated from the same fraction containing pn4c, as a peptide with unknown functions.
title: ADCO, Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Cart. 168 (11 H 66), f. 0200r
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2010
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0200r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0200r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Netzbelastung durch Nullenergiegebäude (Schlussbericht Netzbelastung durch Nullenergiegebäude)
Creators: name: Hall, Monika
name: Geissler, Achim
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2014
Subjects: Eigenverbrauch
Netzbelastung
Wärmespeicherfähigkeit
Thermische Gebäudesimulation
Wärmepumpe

description: Üblicherweise speisen Gebäude mit Photovoltaikanlagen einen Grossteil des Ertrags in das öffentliche Stromnetz ein. Um den Eigenverbrauch zu erhöhen, bietet es sich bei gut gedämmten Gebäuden an, die Laufzeit der Wärmepumpe auf die Tageszeit zu limitieren. Dabei muss der thermische Komfort gewährleistet bleiben. In diesem Zusammenhang wird der Einfluss der Wärmespeicherfähigkeit des Gebäudes auf die operativen Temperaturen in Abhängigkeit von verschiedenen Laufzeiten der Wärmepumpe mit einer thermischen Gebäudesimulation untersucht und mit Messwerten von einem kleinen Mehrfamilienhaus validiert. Es wird gezeigt, dass auch bei einem sehr gut gedämmten Gebäude eine mittlere bis hohe Wärmespeicherfähigkeit vorhanden sein muss, damit die Laufzeit der Wärmepumpe ohne Komforteinbusse auf die Tagesstunden limitiert werden kann. Mit einem Leichtbau ist die gewählte Strategie nicht möglich. Die lange tägliche Sperrzeit bedingt, dass gegenüber dem kontinuierlichen Betrieb die operative Temperatur grösseren Schwankungen unterworfen ist. Das Niveau und die Breite des zulässigen Temperaturbandes müssen mit den normativen Anforderungen für die Behaglichkeit abgestimmt sein. Die Diskussion über normative Behaglichkeitsanforderungen versus energetische Flexibilität des Gebäudes muss lanciert werden.
Industrie 4.0 – Chancen und Risiken
Creators: name: Fischer, Dieter
name: Wäfler, Toni
Publisher: name: MEDISER VSAO-ASMAC
Year: 2016
Subjects: Industrie 4.0
Digitalisierung
IoT
Cyber-Physische Systeme
Dienstleistungsorientierung
Intelligente Automation

description: Aus Angst vor Arbeitslosigkeit zerstörten Handwerker im frühen 19. Jahrhundert die neuen Maschinen und Fabriken. Steht uns Ähnliches bevor? Denn die Technik wird immer intelligenter und produziert ohne menschliches Zutun nicht nur Waren, sondern erbringt zunehmend anspruchsvollere Dienstleistungen. Welche Rolle spielt der Mensch in der Industrie 4.0?
Additional file 3 of The impact of direct challenges to student endorsement of teleological reasoning on understanding and acceptance of natural selection: an exploratory study
Creators: name: Wingert, Jason R.
name: Bassett, Gennie M.
name: Terry, Caitlin E.
name: Lee, Jimin
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3. Between- and within-group differences.
Mit Technologie zur Ideengenerierung
Creators: name: Berga, Janina
Publisher: name: Netzmedien
Year: 2016
Subjects: subject: 330 - Wirtschaft

description: Wie kann man Technologien im Ideenfindungsprozess nutzen, um neue Perspektiven und Potenziale zu identifizieren? Dieser Artikel beschreibt, wie innovative Gadgets wie Virtual-Reality-Brillen und Motion Controller, die der Spiele-Industrie entspringen, helfen, Ideen für die Anwendung in anderen Bereichen zu finden.
Modellbasierte Mengenermittlung – Verschiedene Programme im Vergleich
Creators: name: Herrmann, Florence
name: Herrmann, Yves
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2018
Subjects: BIM
Digitales Bauen
BIM-Modell

description: Die in der Architektur üblichen CAD-Systeme haben ihre Stärken in der Planung eines Bauwerkes bezüglich dessen Konstruktion und seiner graphischen Darstellung. Für die Kostenermittlung benötigt es deshalb weitere Softwaresysteme welche die Mengen nach den in der Schweiz üblichen Ausmassregelungen auswerten und überliefern können.
Long-term outcomes of over 8,000 medial Oxford Phase 3 Unicompartmental Knees—a systematic review
Creators: name: Mohammad, Hasan R
name: Strickland, Louise
name: Hamilton, Thomas W
name: Murray, David W
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Background and purpose — There is debate as to the relative merits of unicompartmental and total knee arthroplasty (UKA, TKA). Although the designer surgeons have achieved good results with the Oxford UKA there is concern over the reproducibility of these outcomes. Therefore, we evaluated published long-term outcomes of the Oxford Phase 3 UKA. Patients and methods — We searched databases to identify studies reporting ≥10 year outcomes of the medial Oxford Phase 3 UKA. Revision, non-revision, and re-operation rates were calculated per 100 component years (% pa). Results — 15 studies with 8,658 knees were included. The annual revision rate was 0.74% pa (95% CI 0.67–0.81, n = 8,406) corresponding to a 10-year survival of 93% and 15-year survival of 89%. The non-revision re-operation rate was 0.19% pa (95% CI 0.13–0.25, n = 3,482). The re-operation rate was 0.89% pa (95% CI 0.77–1.02, n = 3,482). The most common causes of revision were lateral disease progression (1.42%), aseptic loosening (1.25%), bearing dislocation (0.58%), and pain (0.57%) (n = 8,658). Average OKS scores were 40 at 10 years (n = 3,417). The incidence of medical complications was 0.83% (n = 1,443). Interpretation — Very good outcomes were achieved by both designer and non-designer surgeons. The PROMs, medical complication rate, and non-revision re-operation rate were better than those found in meta-analyses and publications for TKA but the revision rate was higher. However, if failure is considered to be all re-operations and not just revisions, then the failure rate of UKA was less than that of TKA.
Additional file 1 of PET/MR fusion texture analysis for the clinical outcome prediction in soft-tissue sarcoma
Creators: name: Zhao, Wenzhe
name: Huang, Xin
name: Wang, Geliang
name: Guo, Jianxin
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1.
Using Insights from Video Games to Support Formal Education – A Conceptual Exploration
Creators: name: Bremm, Nina
name: Brown, Chris
name: Krammer, Georg
name: Tulowitzki, Pierre
Publisher: name: Waxmann
Year: 2019
Subjects: subject: Videospiel
subject: Bildung
subject: Schule
subject: Weiterbildung
subject: Achievements
subject: Schulen in herausfordernder Lage
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Th is article draws upon fi ndings from research on the eff ects of gaming, educational psychology, teacher professionalism as well as school improvement, to develop a framework for linking video game activities to formal education. Th is framework uses video game achievements – virtual trophies received for completing tasks or mastering challenges – as a proxy indicator for the development of competencies relevant to formal education. We suggest that this knowledge can be harnessed to improve teaching and learning, in particular teacher perceptions, teaching skills, and, ultimately, measurable changes in students’ learning. Showing teachers what students can actually do and are already doing (in video games) could help them better understand areas of strength and interest of their students.
Computational analysis of the early stage of cuprous oxide sulphidation: a top-down process
Creators: name: J. H. Stenlid
name: A. J. Johansson
name: C. Leygraf
name: T. Brinck
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The initial steps of Cu2O sulphidation to Cu2S have been studied using plane-wave density functional theory at the PBE-D3+U level of sophistication. Surface adsorption and dissociation of H2S and H2O, as well as the replacement reaction of lattice oxygen with sulphur, have been investigated for the most stable (111) and (100) surface facets under oxygen-lean conditions. We find that the (100) surface is more susceptible to sulphidation than the (111) surface, promoting both H2S adsorption, dissociation and the continued oxygen–sulphur replacement. The results presented in this proceeding bridge previous results from high-vacuum experiments on ideal surface to more realistic corrosion conditions and set the grounds for future mechanistic studies. Potential implications on the long-term final disposal of spent nuclear fuel are discussed. This paper is part of a supplement on the 6th International Workshop on Long-Term Prediction of Corrosion Damage in Nuclear Waste Systems.
Modeling the fiscal costs and benefits of alternative treatment strategies in the United Kingdom for chronic hepatitis C
Creators: name: Connolly, Mark P.
name: Kotsopoulos, Nikos
name: Ustianowski, Andrew
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Background: Hepatitis C (HCV) infection causes substantial direct health costs, but also impacts broader societal and governmental costs, such as tax revenue and social protection benefits. This study investigated the broader fiscal costs and benefits of curative interventions for chronic Hepatitis C (CHC) that allow individuals to avoid long-term HCV attributed health conditions. Methods: A prospective cohort model, assessing the long-term fiscal consequences of policy decisions, was developed for HCV infected individuals, following the generational accounting analytic framework that combines age-specific lifetime gross taxes paid and governmental transfers received (i.e. healthcare and social support costs). The analysis assessed the burden of a theoretical cohort of untreated HCV infected patients with the alternative of treating these patients with a highly efficacious curative intervention (ledipasvir/sofosbuvir [LDV/SOF]). It also compared treating patients at all fibrosis stages (Stages F0–F4) compared to late treatment (Stage F4). Results: Based on projected lifetime work activity and taxes paid, the treated cohort paid an additional £5,900 per patient compared to the untreated cohort. Lifetime government disability costs of £97,555 and £125,359 per patient for treated cohort vs no treatment cohort were estimated, respectively. Lifetime direct healthcare costs in the treated cohort were £32,235, compared to non-treated cohort of £26,424, with an incremental healthcare costs increase of £5,901 per patient. The benefit cost ratio (BCR) of total government benefits and savings relative to government treatment costs (including LDV/SOF) ranged from 1.8–5.6. Treating patients early resulted in 77% less disability costs, 43% lower healthcare costs, and 33% higher tax revenue. Conclusion: The ability to cure Hepatitis C offers considerable fiscal benefits beyond direct medical costs and savings attributed to reduced disability costs, public allowances, and improved tax revenue. Changes in parameters, such as productivity, wage growth, and tax rates, can influence the conclusions described here.
Explaining public perception and acceptance of risks: It’s all about trust
Creators: name: Visschers, Vivianne
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2019
Subjects: subject: risk perception
subject: technological risks
subject: trust
subject: affect
subject: perceived fairness
subject: 334 - Natürliche Ressourcen, Energie und Umwelt
subject: 150 - Psychologie

description: In order to raise public acceptance of a new technology or to stimulate laypeople to mitigate an environmental risk, it is important to understand how laypeople perceive them. The aim of my talk therefore is to discuss how people perceive risks and what determines their acceptance of a hazard in order to provide practical implications for risk management and communication. I will focus on various possible determinants (i.e. perceived benefits, trust, knowledge, affective associations and procedural fairness) and will review findings from studies about several technological and environmental hazards (e.g. nuclear power, carbon capture and storage and climate change). Overall, I will show that public acceptance of technological and environmental risks is mainly related to three factors: trust in stakeholders, affective associations with, and perceived benefits of the hazard. Trust constitutes the most important underlying determinant of the perception and acceptance of technological and environmental hazards. Risk managers are therefore recommended to build and maintain a trustworthy relationship with the public.
Arbeitsbelastungen von Schlüssel-Funktionären in nationalen Schweizer Sportverbänden – Analyse und Ermittlung von Handlungsvorschlägen
Creators: name: Eggli, Caroline
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2019

description: Die vorliegende Bachelorarbeit geht der Frage nach, welche psychischen Belastungen und Beanspruchungen bei den Schlüssel-Funktionären Chef/in Leistungssport und Chef/in Nachwuchs vorliegen und welche Handlungsvorschläge diese negativen Beanspruchungen reduzieren können. Zur Beantwortung dieser Fragen wurden Befunde aus der Literatur, eine Be-fragung (N = 71) und eine Fokusgruppe eingesetzt. Die Ergebnisse zeigen, dass hohe Anforderungen an die Funktionäre gestellt werden, diese jedoch auch ein hohes Arbeitsengage-ment zeigen. Die Auseinandersetzung der Ergebnisse in der Fokusgruppe zeigte, dass die Eigenverantwortung beim Umgang mit Arbeitsbelastungen eine grosse Rolle spielt.
title: ADCO, Ordre cistercien : comptes (1499-1515) (11 H 1162), f. 00306
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1499-1515), Archives départementales de la Côte-d'Or, (11 H 1162), f. 00306, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
Additional file 2 of DEPTH2: an mRNA-based algorithm to evaluate intratumor heterogeneity without reference to normal controls
Creators: name: Song, Dandan
name: Wang, Xiaosheng
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 2: Figure S1. Kaplan–Meier curves showing that higher-DEPTH2-score (> median) tumors have more inferior overall survival and disease-specific survival than lower-DEPTH2-score (
Albert der Große: Über das Gewissen und den praktischen Intellekt. Eine Textauswahl aus De homine, den Quaestiones und De anima. Lateinisch – Deutsch, hg. v. Henryk Anzulewicz / Philipp Andreas C. Anzulewicz
Creators: name: Grotz, Stephan
Publisher: name: Theologische Revue
Year: 2020

description: Theologische Revue, Bd. 116 (2020): Februar
Additional file 3 of DEPTH2: an mRNA-based algorithm to evaluate intratumor heterogeneity without reference to normal controls
Creators: name: Song, Dandan
name: Wang, Xiaosheng
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 3: Figure S2. Associations of tumor purity-adjusted DEPTH2 ITH with genomic instability, antitumor immune signatures, tumor progressive phenotypes, and survival prognosis in cancer. (A) Significant positive correlations between tumor purity-adjusted DEPTH2 scores and genomic instability features (TMB, CNA, and HRD) in diverse cancers. (B) Significant negative correlations between tumor purity-adjusted DEPTH2 scores and antitumor immune signatures (CD8+ T cells, NK cells, immune cytolytic activity, and IFN response) in diverse cancers. (C) Significant positive correlations between tumor purity-adjusted DEPTH2 scores and tumor stemness scores in 11 cancer types. (D) DEPTH2 scores are significantly higher in advanced versus non-advanced [late-stage (stage III–IV) versus early-stage (stage I–II), high-grade (G3–4) versus low-grade (G1–2), and metastatic versus primary] tumors in diverse cancers (one-tailed Mann–Whitney U test, P median) have more inferior overall survival and disease-specific survival than the tumors with lower tumor purity-adjusted DEPTH2 scores (
title: Wellbeing among adolescents and young adults in sub-Saharan Africa: a mixed methods study of their wellbeing construct, its health correlates and association with access to HIV treatment
Creators: name: Govindasamy, D
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2022

description: Improving wellbeing among adolescents and young adults aged 15 to 34 years forms an integral part of universal health coverage and sustainable development in sub- Saharan Africa (SSA). However, data on the wellbeing effects of policies and programmes for this age-group remain scarce, despite this being a key Sustainable Development Goal. The lack of evidence on wellbeing determinants and measures are key barriers to the design and evaluation of wellbeing policies and programmes. This thesis contributes towards informing wellbeing measures for policy evaluations and identifying policies and programmes that may be effective in promoting wellbeing among this population. In this thesis I aim to investigate appropriate measures and health determinants of wellbeing among adolescents and young adults in SSA. Using a mixed-methods research design, I first identify the correlates and experiences of wellbeing among young people living with HIV via a mixed-method review. Thereafter, I apply econometric techniques to investigate the relationship between health (mental and physical) and wellbeing; and subsequently examine whether scale-up of HIV treatment, a key public health policy in this setting, has been associated with any wellbeing gains among young people as they transition into adulthood. Lastly, I qualitatively explore the local understandings and experiences of wellbeing among young people living with and without HIV. In my review, I find that social support and belonging were key correlates of wellbeing, and that acceptance and belonging within networks were key in shaping experiences suggestive of wellbeing. In my econometrics study, I find that poor mental health and physical health are negatively associated with wellbeing, and that HIV treatment access is strongly positively correlated with wellbeing. My qualitative study suggests that social integration and social contribution are key dimensions of young people’s wellbeing in this setting. Overall, my thesis supports the use of multi-dimensional relational wellbeing measures for this population. Evaluation of multi-sectoral HIV policies on wellbeing among adolescents and young adults are warranted.
Interactions between genetic variants and near-work activities in incident myopia in schoolchildren: a 4-year prospective longitudinal study
Creators: name: Lin, Yaoyao
name: Jiang, Dandan
name: Li, Chunchun
name: Huang, Xiaoqiong
name: Xiao, Haishao
name: Liu, Linjie
name: Chen, Yanyan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Knowledge of interactions between genetic variants and near-work activities at the onset of myopia can facilitate health education regarding myopia. To investigate the interactions between genetic variants (PDE10A, AREG and GABRR1) and near-work activities in the onset of myopia in southeastern Chinese school children. A total of 458 non-myopic, grade 1 children aged 6–7 years were included in a 4-year follow-up examination; 409 children were assessed further. Manifest (non-cycloplegic) refraction and axial length (AL) were measured every year, and questionnaires were administered annually to assess information regarding the demographic characteristics of children, near-work activities, outdoor exposure and parental myopia. Oral mucosa was collected in the last year of follow-up, and Sanger sequencing was used to genotype single nucleotide polymorphisms (SNPs) in DNA. The cumulative change in the spherical equivalent refraction (SER) over 4 years was −1.20 ± 1.00 D, and the proportion of children with incident myopia was 42.9%. Multivariate logistic regression analysis showed that an increased amount of time spent doing homework (>2 h/d) was an independent risk factor for incident myopia. The PDE10A rs12206610CT genotype and spending > 5 h/d on near-work activities showed an interaction for incident myopia (OR = 4.29, 95% CI: 1.27-14.53; Pinteraction = 0.02); moreover, the rs12206610CT genotype carriers who used electronic devices for > 1 h/d displayed an increased risk of incident myopia (OR = 3.43, 95% CI: 1.07-11.01; Pinteraction = 0.043). The rs2206610CT genotype carriers with near-work activities of >5 h/d were more likely to show incident myopia, especially those who used electronic devices >1 h/d. However, interactions between the rs12206610 SNP and near-work activities require further verification in animal models and larger sample cohorts.
Additional file 1 of Palliative care training: a national study of internal medicine residency program directors in the United Arab Emirates
Creators: name: Ibrahim, Halah
name: Harhara, Thana
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
Modelling the fiscal Costs and benefits of alternative treatment strategies in the United Kingdom for chronic Hepatitis C
Creators: name: Connolly, Mark P.
name: Kotsopoulos, Nikos
name: Ustianowski, Andrew
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Background: Hepatitis C (HCV) infection causes substantial direct health costs, but also impacts broader societal and governmental costs, such as tax revenue and social protection benefits. We investigated the broader fiscal costs and benefits of curative interventions for chronic Hepatitis C (CHC) that allow individuals to avoid long-term HCV attributed health conditions. Methods: A prospective cohort model, assessing the long-term fiscal consequences of policy decisions, was developed for HCV infected individuals, following the generational accounting analytic framework that combines age-specific lifetime gross taxes paid and governmental transfers received (i.e., healthcare and social support costs). The analysis assessed the burden of a theoretical cohort of untreated HCV infected patients with the alternative of treating these patients with a highly efficacious curative intervention (ledipasvir/sofosbuvir [LDV/SOF]). We also compared treating patients at all fibrosis stages (Stage F0-F4) compared to late treatment (Stage F4). Results: Based on projected lifetime work activity and taxes paid the treated cohort paid an additional £5,900 per patient compared to the untreated cohort. Lifetime government disability costs of £97,555 and £125,359 per patient for treated cohort versus no treatment cohort were estimated, respectively. Lifetime direct healthcare costs in the treated cohort were £32,235 compared to non-treated cohort of £26,424 with incremental healthcare costs increase of £5,901 per patient. The benefit cost ratio (BCR) of total government benefits and savings relative to government treatment costs (including LDV/SOF) ranged from 1.8 to 5.6. Treating patients early resulted in 77% less disability costs, 43% lower healthcare costs, and 33% higher tax revenue. Conclusion: The ability to cure Hepatitis C offers considerable fiscal benefits beyond direct medical costs and savings attributed to reduced disability costs, public allowances, and improved tax revenue. Changes in parameters, such as productivity, wage growth, and tax rates, can influence the conclusions described here.
Gravitational waves from compact binaries to the fourth post-Newtonian order
Creators: name: Blanchet, L.
name: Faye, G.
name: Henry, Q.
name: Larrouturou, Francois
name: Trestini, D.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: binary, compact
interaction, nonlinear
higher-order, 0
gravitational radiation
LISA
regularization
gravitation

description: doi:10.3204/PUBDB-2023-02945
description: The precise knowledge of the gravitational phase evolution of compact binaries is crucial to the data analysis for gravitational waves. Until recently, it was known analytically (for non-spinning systems) up to the 3.5 post-Newtonian (PN) order, i.e. up to the $(v/c)^7$ correction beyond the leading order quadrupole formula. Using a PN-multipolar-post-Minkowskian algorithm, we have pushed the accuracy to the next 4PN level. This derivation involved challenging technical issues, due to the appearance of non-physical divergences, which have to be properly regularized, as well as effects of non-linear multipole interactions.
Additional file 1 of Assessment of the impact of green synthesized copper nanoparticles on freshwater snails (Indoplanorbis exustus) in comparison with field-control and lab-control snails
Creators: name: Mehraj, Ahtisham
name: Pandit, Sangeeta V.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. S.1 Weight of snails in gms (13 snails in groups), no significant difference was observed. S.2 Higher concentration of copper nanoparticles had a negative effect on the snails as they secrete more mucus. The arrows represent the mucous secretion. S.3 The haemocytes showed a decline in viability after trypan blue staining.
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00622
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Petot, Frédéric
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: LaMOP
subject: Chartes de la Bourgogne du Moyen Âge
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00622, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Psychological distress trajectories in chronic physical health conditions
Creators: name: Debnar, Caroline
name: Carrad, Valerie
name: Morselli, Davide
name: Michel, Gisela
name: Bachmann, Nicole
name: Peter, Claudio
Publisher: name: American Psychological Association
Year: 2019
Subjects: subject: physical health
subject: Psychological distress trajectories
subject: 300 - Sozialwissenschaften

description: Objective: The onset of a chronic health condition (CHC) can have a severe impact on an individual's life, affecting mental and physical health. This study's goal was to investigate psychological distress trajectories starting from 1 year before to 4 years after the onset of a physical CHC. The specific aims were to identify the number and shape of longitudinal psychological distress trajectories and to test health-related, psychological, social, and demographic factors predicting these trajectories. Method: Two samples were drawn from the Swiss Household Panel data set: a CHC sample (n = 361) and a 1-to-1 matched comparison sample of healthy individuals. Latent growth mixture modeling was used to identify psychological distress trajectories over 6 years. Factors predicting trajectories were then tested using multinomial logistic regression. Results: Four psychological distress trajectories were identified in the CHC sample: resilience (53.9%), chronic (22.2%), delayed (15.0%), and recovery (8.9%). In the comparison sample, two trajectories were identified: low psychological distress (90%) and elevated psychological distress (10%). Protective factors associated with resilient trajectory membership in the CHC sample were higher emotional stability, higher relationship satisfaction, and male gender. Conclusion: Individuals living with a CHC had an increased risk of vulnerability compared with a sample of healthy individuals. This advocates awareness of mental health issues following the onset of a CHC. In this regard, biopsychosocial factors (gender, emotional stability, and relationship satisfaction) offer prevention and intervention opportunities for more vulnerable individuals. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
Modeling the fiscal costs and benefits of alternative treatment strategies in the United Kingdom for chronic Hepatitis C
Creators: name: Connolly, Mark P.
name: Kotsopoulos, Nikos
name: Ustianowski, Andrew
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Background: Hepatitis C (HCV) infection causes substantial direct health costs, but also impacts broader societal and governmental costs, such as tax revenue and social protection benefits. This study investigated the broader fiscal costs and benefits of curative interventions for chronic Hepatitis C (CHC) that allow individuals to avoid long-term HCV attributed health conditions. Methods: A prospective cohort model, assessing the long-term fiscal consequences of policy decisions, was developed for HCV infected individuals, following the generational accounting analytic framework that combines age-specific lifetime gross taxes paid and governmental transfers received (i.e. healthcare and social support costs). The analysis assessed the burden of a theoretical cohort of untreated HCV infected patients with the alternative of treating these patients with a highly efficacious curative intervention (ledipasvir/sofosbuvir [LDV/SOF]). It also compared treating patients at all fibrosis stages (Stages F0–F4) compared to late treatment (Stage F4). Results: Based on projected lifetime work activity and taxes paid, the treated cohort paid an additional £5,900 per patient compared to the untreated cohort. Lifetime government disability costs of £97,555 and £125,359 per patient for treated cohort vs no treatment cohort were estimated, respectively. Lifetime direct healthcare costs in the treated cohort were £32,235, compared to non-treated cohort of £26,424, with an incremental healthcare costs increase of £5,901 per patient. The benefit cost ratio (BCR) of total government benefits and savings relative to government treatment costs (including LDV/SOF) ranged from 1.8–5.6. Treating patients early resulted in 77% less disability costs, 43% lower healthcare costs, and 33% higher tax revenue. Conclusion: The ability to cure Hepatitis C offers considerable fiscal benefits beyond direct medical costs and savings attributed to reduced disability costs, public allowances, and improved tax revenue. Changes in parameters, such as productivity, wage growth, and tax rates, can influence the conclusions described here.
Qualbrink, Andrea: Frauen in kirchlichen Leitungspositionen. Möglichkeiten, Bedingungen und Folgen der Gestaltungsmacht von Frauen in der katholischen Kirche
Creators: name: Hartmann, Richard
Publisher: name: Theologische Revue
Year: 2020

description: Theologische Revue, Bd. 116 (2020): Februar
"Product Advertisement"
Creators: name: Carver, Louise Emily
name: Allen, Jamie
Publisher: name: Tropic Editions
Year: 2019
Subjects: subject: 700 - Künste und Unterhaltung

description: We know that the mensuration of key geo-constitutive elements, such as compositions of carbon, potassium and nitrate containment, as well as their retention and relation to productivity and quality, are of prime importance. We also know how frustrating the notoriously inaccurate and generalized surveys and estimates done by State Laboratory of Development and Production can be for operativity and productivity metrics. The Earth’s own servicing of human needs can vary greatly from pasture to paddock, from grasslands to pasturelands, from one’s European corral to another’s Canadian meadow.
BOLALAR KIYIMLARIGA QО'YILADIGAN TALABLARNING О'ZIGA XOS XUSUSIYATLARINI TAHLIL QILISH
Creators: name: Rаximоvа, Kаmоlа
name: Baynazarova, Lobar
name: Boltayeva, Marjona
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada o’smir yoshdagi bolalarning o’ziga xos madaniyatining turlari, yoshlar garderobiga qanday kiyimlarni kiritishimiz mumkinligi va ularning qaysi juhatlariga e’tibor berishimiz kerakligini, o’smir yoshdagi bolalarning kiyadigan kiyimlariga qo’yiladigan talablarning o’ziga xos xususiyatlari tahlil qilingan.
Additional file 1 of A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis
Creators: name: Wang, Yi-Wei
name: Chen, Shu-Chuan
name: Gu, De-Leung
name: Yeh, Yi-Chen
name: Tsai, Jhih-Jie
name: Yang, Kuo-Tai
name: Jou, Yuh-Shan
name: Chou, Teh-Ying
name: Tang, Tang K.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Additional Tables S1–S4.
Supplementary Figures from MicroRNA-22 coordinates vascular and motor neuronal pathfinding via sema4 during zebrafish development
Creators: name: Sheng, Jiajing
name: Gong, Jie
name: Shi, Yunwei
name: Wang, Xin
name: Liu, Dong
Publisher: name: The Royal Society
Year: 2022

description: A precise guiding signal is crucial to orchestrate directional migration and patterning of the complex vascular network and neural system. So far, limited studies have reported the discovery and functions of microRNAs (miRNAs) in guiding vascular and neural pathfinding. Currently, we showed that the deficiency of miRNA-22a, an endothelial-enriched miRNA, caused dramatic pathfinding defects both in intersegmental vessels (ISVs) and primary motor neurons (PMNs) in zebrafish embryos. Furthermore, we found the specific inhibition of miR-22a in ECs resulted in the patterning defects of both ISVs and PMNs. Neuronal block of miR-22a mainly led to the axonal defects of PMN. Sema4c was identified as a potential target of miR-22a through transcriptomic analysis and in silico analysis. Furthermore, the luciferase assay and EGFP sensor assay confirmed the binding of miR-22a with 3′-UTR of sema4c. In addition, downregulation of sema4c in the miR-22a morphants significantly neutralized the aberrant patterning of vascular and neural networks. Then we demonstrated that endothelial miR-22a regulates PMNs axonal navigation. Our study revealed that miR-22a acted as a dual regulatory cue coordinating vascular and neuronal patterning and expanded the repertoire of regulatory molecules, which might be of use therapeutically to guide vessels and nerves in the relevant diseases.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Cart. 189 (11 H 74), 316 folios, f. 0171v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0171v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0171v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Challenges of feedback provision in the workplace: A qualitative study of emergency medicine residents and teachers
Creators: name: Chung-Hsien Chaou
name: Monrouxe, Lynn V.
name: Chang, Li-Chun
name: Shiuan-Ruey Yu
name: Chip-Jin Ng
name: Ching-Hsing Lee
name: Yu-Che Chang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: 110309 Infectious Diseases

description: Background: Feedback is an effective pedagogical tool in clinical teaching and learning, but is often perceived as unsatisfactory. Little is known about the effect of a busy clinical environment on feedback-giving and -seeking behaviors. This study aims to determine the perceptions and challenges of feedback provision in a busy clinical setting, exemplified by an emergency department (ED). Methods: A qualitative semi-structured interview study design was employed. Thirty-six participants (18 attending physicians, 18 residents) were purposively sampled from three EDs in northern Taiwan between August 2015 and July 2016. Interviews were recorded, transcribed, and analyzed thematically. Results: Three major themes were identified with illustrative quotes: (1) the balance between patient safety and providing feedback, (2) variability in feedback, and (3) influential factors, barriers and enablers. Conclusions: In real practice, clinical duties competed with the impulse to provide feedback. The variety and complexity of feedback extended beyond style and content. Clinical and contextual factors – some of which may be presented as barriers – influenced how, when and whether a teacher or learner decided to give or seek feedback.
Visualizing the Electrical Structure of Power Systems
Creators: name: Cuffe, Paul
name: Keane, Andrew
Publisher: name: figshare
Year: 2017
Subjects: subject: 120307 Visual Communication Design (incl. Graphic Design)
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Author's copy of a paper in IEEE Systems journal which used electrical distance metrics to draw meaningful diagrams of electric power systems.