cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Computational investigation on the effects of pharmaceutical polymers on the structure and dynamics of interleukin2 in heat stress
Creators: name: Moradi, Sajad
name: Mirzaei, Saba
name: Khosravi, Rasool
name: Farhadian, Negin
name: koushki, Elnaz Hosseininezhadian
name: Shahlaei, Mohsen
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Application of proteinous drugs can be associated with difficulties during both in storage/transportation and in the body when they are used. However, using pharmaceutical carbohydrates that are widely employed in drug delivery systems, besides the drug can be protected, these systems leading to gradually release the drug over time, or deliver it to the target cell. Using a combination of molecular modeling and simulation techniques, in this study the effects of five carbohydrate polymers of Chitosan, Alginate, Cyclodextrin, Hyaluronic acid and Pectin on structure and dynamics of interleukin2 protein at 298 K and 343 K, are investigated. Data achieved using molecular modeling methods showed that when the temperature rises, the protein stability decreases. Among different polymers, Chitosan and Cyclodextrin have shown to be able to protect protein against the negative effects of high temperatures in comparison with other polymers which suggests that the use of Cyclodextrin biopolymer for the preparation of pharmaceutical formulations of interleukin2 can be the best possible choice among other polymers investigated in this research. Communicated by Ramaswamy H. Sarma
IVOA Recommendation: VODataService: a VOResource Schema Extension for Describing Collections and Services Version 1.1
Creators: name: Plante, Raymond
name: Stébé, Aurélien
name: Benson, Kevin
name: Dowler, Patrick
name: Graham, Matthew
name: Greene, Gretchen
name: Harrison, Paul
name: Lemson, Gerard
name: Linde, Tony
name: Rixon, Guy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: VODataService refers to an XML encoding standard for a specialized extension of the IVOA Resource Metadata that is useful for describing data collections and the services that access them. It is defined as an extension of the core resource metadata encoding standard known as VOResource [Plante et al. 2008] using XML Schema. The specialized resource types defined by the VODataService schema allow one to describe how the data underlying the resource cover the sky as well as cover frequency and time. This coverage description leverages heavily the Space-Time Coordinates (STC) standard schema [Rots 2007]. VODataService also enables detailed descriptions of tables that includes information useful to the discovery of tabular data. It is intended that the VODataService data types will be particularly useful in describing services that support standard IVOA service protocols.
Virtualization Implementation Model for Cost Effective & Efficient Data Centers
Creators: name: Uddin, Mueen
name: Rahman, Azizah Abdul
Publisher: name: arXiv
Year: 2012
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Data centers form a key part of the infrastructure upon which a variety of information technology services are built. They provide the capabilities of centralized repository for storage, management, networking and dissemination of data. With the rapid increase in the capacity and size of data centers, there is a continuous increase in the demand for energy consumption. These data centers not only consume a tremendous amount of energy but are riddled with IT inefficiencies. Data center are plagued with thousands of servers as major components. These servers consume huge energy without performing useful work. In an average server environment, 30% of the servers are "dead" only consuming energy, without being properly utilized. This paper proposes a five step model using an emerging technology called virtualization to achieve energy efficient data centers. The proposed model helps Data Center managers to properly implement virtualization technology in their data centers to make them green and energy efficient so as to ensure that IT infrastructure contributes as little as possible to the emission of greenhouse gases, and helps to regain power and cooling capacity, recapture resilience and dramatically reducing energy costs and total cost of ownership.
description: 6 pages, 1 Figure, Journal Paper. arXiv admin note: substantial text overlap with arXiv:1010.5037
title: Kommunizieren lernen mit eLearning und audiovisuellen Medien – konkrete Beispiele und Diskussion
Creators: name: Karsten, Gudrun
name: Moeller, Grit
name: Rockenbauch, Katrin
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 3-20    Lernziele: Das Training kommunikativer Kompetenzen kann durch die Einbettung von eLearning bzw. dessen medialen Elementen erfolgreich ergänzt werden [ref:1].      Daher stellen wir im Workshop bereits entwickelte Unterrichtsmedien / eLearning-Module[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Curriculum Mapping zu Fehlern in der Medizin und Patientensicherheit
Creators: name: Kiesewetter, Jan
name: Welbergen, Lena
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 5-20    Lernziele: Der Ausschuss für Patientensicherheit und Fehler in der Medizin arbeitet seit seiner Gründung im Herbst 2013 an der Erstellung eines Lernzielkataloges, welcher an medizinischen Fakultäten im deutschsprachigen Raum in das Curriculum integriert [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Einheitliche Mindeststandards bei Einsätzen von Simulationspatienten – Erarbeitung eines Positionspapiers
Creators: name: Peters, Tim
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 6-20    Lernziele: Der Einsatz von Simulationspatienten (SP) hat sich in der medizinischen Ausbildung in Deutschland inzwischen etabliert und ist aus Lehre und Prüfungen nicht mehr wegzudenken. Dabei spielen SP sowohl im Unterricht von Untersuchungstechniken als auch in der[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Virtual screening and dynamics of potential inhibitors targeting RNA binding domain of nucleocapsid phosphoprotein from SARS-CoV-2
Creators: name: Yadav, Rohitash
name: Imran, Mohammed
name: Dhamija, Puneet
name: Suchal, Kapil
name: Handu, Shailendra
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The emergence of the coronavirus disease-2019 pandemic has led to an outbreak in the world. The SARS-CoV-2 is seventh and latest in coronavirus family with unique exonucleases for repairing any mismatches in newly transcribed genetic material. Therefore, drugs with novel additional mechanisms are required to simultaneously target and eliminate the virus. Thus, a newly deciphered N protein is taken as a target that belongs to SARS-CoV-2. They play a vital role in RNA transcription, viral replication and new virion formation. This study used virtual screening, molecular modeling and docking of the 8987 ligands from Asinex and PubChem databases against this novel target protein. Three hotspot sites having DScore ≥1 (Site 1, Site 2 and Site 3) for ligand binding were selected. Subsequently, high throughput screening, standard precision and extra precision docking process and molecular dynamics concluded three best drugs from two libraries. Two antiviral moieties from Asinex databases (5817 and 6799) have docking scores of −10.29 and −10.156; along with their respective free binding energies (ΔG bind) of −51.96 and −64.36 on Site 3. The third drug, Zidovudine, is from PubChem database with docking scores of −9.75 with its binding free energies (ΔG bind) of −59.43 on Site 3. The RMSD and RMSF were calculated for all the three drugs through molecular dynamics simulation studies for 50 ns. Zidovudine shows a very stable interaction with fluctuation starting at 2.4 Å on 2 ns and remained stable at 3 Å from 13 to 50 ns. Thus, paving the way for further biological validation as a potential treatment. Communicated by Ramaswamy H. Sarma
Azimuthal distributions of radial momentum and velocity in relativistic heavy ion collisions
Creators: name: Li, Lin
name: Li, Na
name: Wu, Yuanfang
Publisher: name: arXiv
Year: 2012
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Azimuthal distributions of radial (transverse) momentum, mean radial momentum, and mean radial velocity of final state particles are suggested for relativistic heavy ion collisions. Using transport model AMPT with string melting, these distributions for Au + Au collisions at 200 GeV are presented and studied. It is demonstrated that the distribution of total radial momentum is more sensitive to the anisotropic expansion, as the anisotropies of final state particles and their associated transverse momentums are both counted in the measure. The mean radial velocity distribution is compared with the radial °ow velocity. The thermal motion contributes an isotropic constant to mean radial velocity.
Biological and molecular modeling studies on some transition metal(II) complexes of a quinoxaline based ONO donor bishydrazone ligand
Creators: name: Johnson, Jijo
name: Dhanaraj, C. Justin
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: In this report, synthesis, characterization, biological and molecular modeling studies of an ONO donor tridentate bishydrazone ligand, 3-[N′-(2-Hydroxy-3-methoxy-benzylidene)-hydrazino]-1H-quinoxalin-2-one (HHQ) and its 1:1 mononuclear Co(II) (HHQ-1), Ni(II) (HHQ-2), Cu(II) (HHQ-3) and Zn(II) (HHQ-4) complexes have been conferred. Octahedral geometry was assigned to HHQ-1, HHQ-2 and HHQ-4 and distorted octahedral geometry for HHQ-3. The lattice parameters, morphology and electrochemical behaviors of the compounds were studied by powder XRD, SEM and cyclic voltammetry analyses respectively. The antimicrobial assays were carried out against the bacterial (Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa) and fungal (Aspergillus flavus, Aspergillus niger and Candida albicans) strains. Furthermore, the DNA binding, cleaving and superoxide dismutase (SOD) activities of HHQ and its metal(II) complexes were discussed. The structures of HHQ and its derivatives were optimized by DFT techniques. Using molecular docking the molecular interaction dynamics amongst the DNA and SOD with HHQ and its metal(II) complexes were recognized. Communicated by Ramaswamy H. Sarma
Bio-Polymer Hairpin Loops Sustained by Polarons
Creators: name: Chakrabarti, B.
name: Piette, B.
name: Zakrzewski, W. J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We show that polarons can sustain loop-like configurations in flexible bio-polymers and that the size of the loops depend on both the flexural rigidity of the polymer and the electron-phonon coupling constant. In particular we show that for single stranded DNA (ssDNA) such loops can have as little as 10 base pairs. For polyacetylene the shortest loop must have at least 12 nodes. We also show that these configurations are very stable under thermal fluctuations and can facilitate the formation of hairpin-loops of ssDNA.
description: 18 pages, 7 figures, and 1 table
title: Interkulturelle Öffnung und Willkommenskultur in Fakultät, Klinik und Verwaltung
Creators: name: Albrecht, Niels-Jens
name: Arnold, Ulrike
name: Grimm, Franziska
name: Naghavi, Baharan
name: Bath, Anja
name: Djadran, Helei
name: Astfalk, Timo
name: Jacobs, Fabian
name: Thömen-Suhr, Doris
name: Cahoj, Paul
name: Spang, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 5-20    Lernziele: In unserem Medizinsystem arbeiten und lehren wir in internat. Teams. Wir versorgen zunehmend mehr internat. Patienten, aber nur in wenigen Fakultäten und Kliniken findet die erforderliche Lehre hierfür und die Ausbildung mit qualitätsgesicherten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Влияние гидрологических условий на продуктивность березовых древостоев в Новгородской области
Creators: name: Балун, Ольга
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2021

description: В статье рассматривается вопрос продуктивности лиственных лесов в природно-климатических условиях Новгородской области на землях различной степени влажности: отчасти влажных, влажных и сырых. Исследуемой породой является береза. Для анализа используются таксационные характеристики: высота древостоя, диаметр главной породы, запас. Гидрологические условия существенно повлияли на средний
диаметр и величину запаса: продуктивность влажного березняка-долгомошника и отчасти влажного березняка осокового более чем в 2,5 раза была ниже продуктивности березняка-черничника свежего. Существенной разницы между запасами березового древостоя в долгомошном и осоковом типе леса не обнаружено. Данная тенденция прослеживается и при анализе запаса березового древостоя. Для повышения продуктивности влажного и отчасти влажного березняка рекомендуется проведение осушительных мероприятий.
Chandra High resolution Observations of CID-42, a candidate recoiling SMBH
Creators: name: Civano, F.
name: Elvis, M.
name: Lanzuisi, G.
name: Aldcroft, T.
name: Trichas, M.
name: Bongiorno, A.
name: Brusa, M.
name: Blecha, L.
name: Comastri, A.
name: Loeb, A.
name: Salvato, M.
name: Fruscione, A.
name: Koekemoer, A.
name: Komossa, S.
name: Gilli, R.
name: Mainieri, V.
name: Piconcelli, E.
name: Vignali, C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present Chandra High Resolution Camera observations of CID-42, a candidate recoiling supermassive black hole (SMBH) at z=0.359 in the COSMOS survey. CID-42 shows two optical compact sources resolved in the HST/ACS image embedded in the same galaxy structure and a velocity offset of ~1300 km/s between the Hβ broad and narrow emission line, as presented by Civano et al. (2010). Two scenarios have been proposed to explain the properties of CID-42: a GW recoiling SMBH and a double Type 1/ Type 2 AGN system, where one of the two is recoiling because of slingshot effect. In both scenario, one of the optical nuclei hosts an unobscured AGN, while the other one, either an obscured AGN or a star forming compact region. The X-ray Chandra data allow to unambiguously resolve the X-ray emission, and unveil the nature, of the two optical sources in CID-42. We find that only one of the optical nuclei is responsible for the whole X-ray unobscured emission observed and a 3sigma upper limit on the flux of the second optical nucleus is measured. The upper limit on the X-ray luminosity plus the analysis of the multiwavelength spectral energy distribution indicate the presence of a starforming region in the second source rather than an obscured SMBH, thus favoring the GW recoil scenario. However the presence of a very obscured SMBH cannot be fully ruled-out. A new X-ray feature, in a SW direction with respect to the main source, is discovered and discussed.
description: Accepted for publication in ApJ on April 10, 2012. 7 pages, 7 figures
Evénements
Creators: name: Redaktion, Die
Publisher: name: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft
Year: 2019

description: Jahresbericht SIK-ISEA / Schweizerisches Institut für Kunstwissenschaft, 2016: Jahresbericht 2015 SIK-ISEA
Synthesis, molecular modelling, FT-IR, Raman and NMR characterization, molecular docking and ADMET study of new nickel(II) complex with an N4-tetradentate thiosemicarbazone
Creators: name: Eğlence-Bakır, Songül
name: Celik, Sefa
name: Şahin, Musa
name: Ozel, Aysen E.
name: Akyuz, Sevim
name: Ülküseven, Bahri
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: A new nickel(II) complex was synthesized by using S-propyl-thiosemicarbazide and 2-amino-3,5-dibromobenzaldehyde. The complex, obtained by the template effect of nickel ions, was structurally analysed by experimental and theoretical vibrational spectroscopy, NMR and density functional theory (DFT) calculations. By using DFT/B3LYP method with 6-311++G(d, p) basis set, the most stable molecular structure of the title molecule was calculated. The fundamental vibrational wavenumbers, IR and Raman intensities for the optimized structure of the molecule under investigation were determined and compared with the experimental vibrational spectra. The vibrational assignment was achieved using the calculated potential energy distributions of the vibrational modes. Moreover, the molecular electrostatic potential (MEP), the highest occupied molecular orbital (HOMO) and the lowest occupied molecular orbital (LUMO) energies were calculated, Molecular docking of the molecule was carried out against DNA in order to identify the potential inhibitory action of the title compound. The findings suggested that the aforementioned compound has a strong binding affinity to interact with DNA residues DT8, DC9, DG12, DG16, DA17, and DA18 through the intermolecular hydrogen bonds. Also the performed in silico ADMET analysis was the prediction of the synthesized molecule’s pharmacokinetic and toxicity profile expressing good oral drug like actions and non-toxic nature. The complex has been shown to have the possibility to become a model molecule for drug development processes. Communicated by Ramaswamy H. Sarma
title: Ist Frau Dr. Huber heute gar nicht da? Ein Sprechstunden-OSCE in der Allgemeinmedizin – von der Konzeption bis zum Feedback für Studierende
Creators: name: Kiessling, Claudia
name: Härtl, Anja
name: Huenges, Bert
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 10-20    Lernziele: Die Teilnehmerinnen und Teilnehmer sind am Ende des Workshops in der Lage,      Kriterien für einen allgemeinmedizinisch ausgerichteten OSCE Blueprint zu definieren  Einen OSCE-Parcour, der in einem Sprechstunden-Setting angesiedelt ist, zu entwickeln [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Aus Trümmern erstanden: Der Neuanfang im Westteil der Stadt (1945-1963)
Creators: name: Nawroth, Manfred
Publisher: name: Acta Praehistorica et Archaeologica
Year: 2020

description: Acta Praehistorica et Archaeologica, Bd. 36/37 2004/2005(2005)
title: Wie kann Lehre durch Evaluation verbessert werden?
Creators: name: Pignotti, Tanja
name: Wibbecke, Gerald
name: Giesler, Marianne
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 5-18    Lernziele: Ein erfolgreiches Qualitätsmanagementsystem der Lehre führt zu Verbesserungen der Lehre. Darüber hinaus soll es von Lehrenden als hilfreich erachtet und von den Studierenden als wirksam erlebt werden. Die bloße Erhebung, Aufbereitung und [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Dragging two-dimensional discrete solitons by moving linear defects
Creators: name: Brazhnyi, V. A.
name: Malomed, B. A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: Other Condensed Matter (cond-mat.other)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We study the mobility of small-amplitude solitons attached to moving defects which drag the solitons across a two-dimensional (2D) discrete nonlinear-Schrödinger (DNLS) lattice. Findings are compared to the situation when a free small-amplitude 2D discrete soliton is kicked in the uniform lattice. In agreement with previously known results, after a period of transient motion the free soliton transforms into a localized mode pinned by the Peierls-Nabarro potential, irrespective of the initial velocity. However, the soliton attached to the moving defect can be dragged over an indefinitely long distance (including routes with abrupt turns and circular trajectories) virtually without losses, provided that the dragging velocity is smaller than a certain critical value. Collisions between solitons dragged by two defects in opposite directions are studied too. If the velocity is small enough, the collision leads to a spontaneous symmetry breaking, featuring fusion of two solitons into a single one, which remains attached to either of the two defects.
title: Interkulturelle Kompetenz und Global Health - Positionspapier
Creators: name: Mews, Claudia
name: Vajda, Christian
name: Fröhlich-Güzelsoy, Leyla
name: Schuster, Sylvie
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 5-20    Lernziele: Mitglieder des GMA-Ausschusses "Interkulturelle Kompetenz und Global Health" aus Deutschland, Österreich und der Schweiz haben im März 2014 damit begonnen, ein Positionspapier zu den wesentlichen Aspekten von Kultureller Kompetenz und Global[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Data Results from Performance Modelling of Local Planners
Creators: name: Vivani
Publisher: name: Zenodo
Year: 2023
Subjects: benchmark

description: Results from the execution of experimental runs of different Local Planners. Data for multiple performance metrics, robot sensor parameters, and environmental characteristics are included in the results. The data set contains the results of many runs performed with various parameter combinations in order to construct a statistical model of Local Planner performance as a function of robot and environment features.
Bidirectional Sorting of Flocking Particles in the Presence of Asymmetric Barriers
Creators: name: Drocco, Jeffrey A.
name: Reichhardt, C. J. Olson
name: Reichhardt, C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We numerically demonstrate bidirectional sorting of flocking particles interacting with an array of asymmetric barriers. Each particle aligns with the average swimming direction of its neighbors according to the Vicsek model and experiences additional steric interactions as well as repulsion from the fixed barriers. We show that particles preferentially localize to one side of the barrier array over time, and that the direction of this rectification can be reversed by adjusting the particle-particle exclusion radius or the noise term in the equations of motion. These results provide a conceptual basis for isolation and sorting of single- and multi-cellular organisms which move collectively according to flocking-type interaction rules.
description: 5 pages, 7 postscript figures
An in silico approach for identification of novel inhibitors as potential therapeutics targeting COVID-19 main protease
Creators: name: Havranek, Brandon
name: Islam, Shahidul M.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Respiratory disease caused by a novel coronavirus, COVID-19, has been labeled a pandemic by the World Health Organization. Very little is known about the infection mechanism for this virus. More importantly, there are no drugs or vaccines that can cure or prevent a person from getting COVID-19. In this study, the binding affinity of 2692 protease inhibitor compounds that are known in the protein data bank, are calculated against the main protease of the novel coronavirus with docking and molecular dynamics (MD). Both the docking and MD methods predict the macrocyclic tissue factor–factor VIIa (PubChem ID: 118098670) inhibitor to bind strongly with the main protease with a binding affinity of −10.6 and −10.0 kcal/mol, respectively. The TF-FVIIa inhibitors are known to prevent the coagulation of blood and have antiviral activity as shown in the case of SARS coronavirus. Two more inhibitors, phenyltriazolinones (PubChem ID: 104161460) and allosteric HCV NS5B polymerase thumb pocket 2 (PubChem ID: 163632044) have shown antiviral activity and also have high affinity towards the main protease of COVID-19. Furthermore, these inhibitors interact with the catalytic dyad in the active site of the COVID-19 main protease that is especially important in viral replication. The calculated theoretical dissociation constants of the proposed COVID-19 inhibitors are found to be very similar to the experimental dissociation constant values of similar protease-inhibitor systems. Communicated by Ramaswamy H. Sarma
Das Museum für Vor- und Frühgeschichte unter der Leitung von Adriaan von Müller - Hinwendung zur Archäologie Berlins
Creators: name: Neumayer, Heino
Publisher: name: Acta Praehistorica et Archaeologica
Year: 2020

description: Acta Praehistorica et Archaeologica, Bd. 36/37 2004/2005(2005)
Effective field investigation of dynamic phase transitions for site diluted Ising ferromagnets driven by a periodically oscillating magnetic field
Creators: name: Akinci, U.
name: Yuksel, Y.
name: Vatansever, E.
name: Polat, H.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Dynamic behavior of a site diluted Ising ferromagnet in the presence of periodically oscillating magnetic field has been analyzed by means of the effective field theory (EFT). Dynamic equation of motion have been solved for a honeycomb lattice ($z=3$) with the help of a Glauber type stochastic process. The global phase diagrams and the variation of the corresponding dynamic order parameter as a function of the Hamiltonian parameters and temperature has been investigated in detail and it has been shown that the system exhibits reentrant phenomena, as well as a dynamic tricritical point which disappears for sufficiently weak dilution.
description: 12 pages, 5 figures
title: Угрозы безопасности лесного комплекса Новгородской области
Creators: name: Виноградова, Ольга
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2021

description: В статье рассмотрены основные опасности, угрожающие лесному комплексу Новгородской области. Выявлены их причины и динамика проявления. Проведен анализ состояния лесов в регионе за последние десять лет. Выделены пожароопасные периоды. Наибольшее количество лесных пожаров зафиксировано в 2010 году, наименьшее – в 2017 году. Приведены данные по распределению количества пожаров по площади обнаружения и их ликвидации. Определен ежегодный ущерб от лесных пожаров и незаконной вырубки. Из результатов исследования видно, что количественный показатель незаконной вырубки лесов в Новгородской области с
каждым годом снижается. Тенденция к улучшению ситуации наметилась ещё в 2018 году. В данной статье также представлены способы идентификации опасностей, создающих угрозу для лесного массива и мероприятия по лесовосстановлению.
Coherent emission from disordered arrays of driven Josephson vortices
Creators: name: Marchesoni, Fabio
name: Savel'ev, Sergey
name: Tachiki, Masashi
name: Nori, Franco
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We propose a mechanism of coherent emission from driven vortices in stacked intrinsic Josephson junctions. In contrast to super-radiance, which occurs only for highly ordered vortex lattices, we predict resonant radiation emission from weakly correlated vortex arrays. Our analytical results for the THz wave intensity, resonance frequencies, and the dependence of THz emission power on dissipation are in good agreement with the ones obtained by recent simulations.
description: 2 figures
title: Videobasierte Selbstkontrolle als innovatives Konzept zur Unterstützung des Erwerbs praktischer Fertigkeiten
Creators: name: Dahmen, Uta
name: Schulze, C.
name: Schindler, C.
name: Dirsch, O.
name: Settmacher, U.
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 5-30    Lernziele: Die Verfügbarkeit von modernen Medien ist in den vergangenen 10 bis 15 Jahren rasant gestiegen. Beinahe jede Studentin und jeder Student verfügt über ein Smartphone und einen Internetzugang. Digitale Videoaufzeichnungsgeräte sind heute aufgrund[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Distance Preserving Graph Simplification
Creators: name: Ruan, Ning
name: Jin, Ruoming
name: Huang, Yan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: Large graphs are difficult to represent, visualize, and understand. In this paper, we introduce "gate graph" - a new approach to perform graph simplification. A gate graph provides a simplified topological view of the original graph. Specifically, we construct a gate graph from a large graph so that for any "non-local" vertex pair (distance higher than some threshold) in the original graph, their shortest-path distance can be recovered by consecutive "local" walks through the gate vertices in the gate graph. We perform a theoretical investigation on the gate-vertex set discovery problem. We characterize its computational complexity and reveal the upper bound of minimum gate-vertex set using VC-dimension theory. We propose an efficient mining algorithm to discover a gate-vertex set with guaranteed logarithmic bound. We further present a fast technique for pruning redundant edges in a gate graph. The detailed experimental results using both real and synthetic graphs demonstrate the effectiveness and efficiency of our approach.
description: A short version of this paper will be published for ICDM'11, December 2011
Die Verbindung des Museums für Vor- und Frühgeschichte mit der Berliner Bodendenkmalpflege seit 1945
Creators: name: Wagner, Karin
Publisher: name: Acta Praehistorica et Archaeologica
Year: 2020

description: Acta Praehistorica et Archaeologica, Bd. 36/37 2004/2005(2005)
Die Sonderausstellungen 1880 bis 2004 und ihre Anlässe
Creators: name: Gringmuth-Dallmer, Eike
Publisher: name: Acta Praehistorica et Archaeologica
Year: 2020

description: Acta Praehistorica et Archaeologica, Bd. 36/37 2004/2005(2005)
Diacetoxy iodobenzene mediated regioselective synthesis and characterization of novel [1,2,4]triazolo[4,3-a]pyrimidines: apoptosis inducer, antiproliferative activities and molecular docking studies
Creators: name: Kamal, Raj
name: Kumar, Ravinder
name: Kumar, Vipan
name: Bhardwaj, Jitender K.
name: Saraf, Priyanka
name: Kumar, Ajay
name: Pandit, Kritika
name: Kaur, Satwinderjeet
name: Chetti, Prabhakar
name: Beura, Satyajit
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Prompt and regioselective synthesis of eleven novel [1,2,4]triazolo[4,3-a]pyrimidines 2a-2k, via intramolecular oxidative-cyclization of 2-(2-arylidenehydrazinyl)-4-methyl-6-phenylpyrimidine derivatives 1a-1k has been demonstrated here using diacetoxy iodobenzene (DIB) as inexpensive and ecofriendly hypervalent iodine(III) reagent in CH2Cl2 at room temperature. Regiochemistry of final product has been established by developing single crystal and studied X-ray crystallographic data for two derivatives 2c and 2h without any ambiguity. These prominent [1,2,4]triazolo[4,3-a]pyrimidines were evaluated for human osteosarcoma bone cancer (MG-63) and breast cancer (MCF-7) cell lines using MTT assay to find potent antiproliferative agent and also on testicular germ cells to find potent apoptotic inducing activities. All compounds show significant cytotoxicity, particularly 3-(2,4-dichlorophenyl)-5-methyl-7-phenyl-[1,2,4]triazolo[4,3-a]pyrimidine (2g) was found significant apoptotic inducing molecule, as well as the most potent cytotoxic agent against bone cancer (MG-63) and breast cancer (MCF-7) cell lines with GI50 value 148.96 µM and 114.3 µM respectively. Molecular docking studies has been carried out to see the molecular interactions of synthesized compounds with the protein thymidylate synthase (PBD ID: 2G8D). Communicated by Ramaswamy H. Sarma
title: Aus Fehlern lernen – Einführung in die Methodik der Reflexion
Creators: name: Krieg, Iris
name: Sachs, Patrick
name: Stenzel, Marit
name: Bach, Annika
name: Rühl, Friederike
name: Berg, Angela
name: Streitlein-Böhme, Irmgard
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 10 - 24    Lernziele: Kurzbeschreibung:      In einem einführenden Vortrag vermitteln wir Ihnen am Beispiel von Behandlungsfehlern in der Medizin die hohe Relevanz der Reflexion praktischer Fertigkeiten in der ärztlichen Ausbildung.    Darauf aufbauend erarbeiten Sie[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Mechanochemical modeling of dynamic microtubule growth involving sheet-to-tube transition
Creators: name: Ji, Xiang-Ying
name: Feng, Xi-Qiao
Publisher: name: arXiv
Year: 2011
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Computational Physics (physics.comp-ph)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Microtubule dynamics is largely influenced by nucleotide hydrolysis and the resultant tubulin configuration changes. The GTP cap model has been proposed to interpret the stabilizing mechanism of microtubule growth from the view of hydrolysis effects. Besides, the microtubule growth involves the closure of a curved sheet at its growing end. The curvature conversion also helps to stabilize the successive growth, and the curved sheet is referred to as the conformational cap. However, there still lacks theoretical investigation on the mechanical-chemical coupling growth process of microtubules. In this paper, we study the growth mechanisms of microtubules by using a coarse-grained molecular method. Firstly, the closure process involving a sheet-to-tube transition is simulated. The results verify the stabilizing effect of the sheet structure, and the minimum conformational cap length that can stabilize the growth is demonstrated to be two dimers. Then, we show that the conformational cap can function independently of the GTP cap, signifying the pivotal role of mechanical factors. Furthermore, based on our theoretical results, we describe a Tetris-like growth style of microtubules: the stochastic tubulin assembly is regulated by energy and harmonized with the seam zipping such that the sheet keeps a practically constant length during growth.
description: 23 pages, 7 figures. 2 supporting movies have not been uploaded due to the file type restrictions
title: Entrustable Professional Activities (EPAs) in der medizinischen Ausbildung
Creators: name: Kadmon, Martina
name: Berberat, Pascal
name: Holzhausen, Ylva
name: Maaz, Asja
name: Peters, Harm
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 15-25    Lernziele: Hintergrund:     Entrustable Professional Activities (EPAs), auf Deutsch auch „Anvertraubare Professionelle Tätigkeiten (APT)“, werden zunehmend weltweit eingesetzt, um das Lehren und Lernen in kompetenzbasierter medizinischer Ausbildung [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Долговременные эксперименты в лесном хозяйстве
Creators: name: Лебедев, Александр
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2021

description: Для лесного хозяйства особое значение имеют долговременные эксперименты. Организация лесных исследовательских станций в странах Европы и в России началась во второй половине XIX века, когда в среде ведущих ученыхлесоводов сформировалось мнение, что достоверные результаты и выводы могут быть
получены только в процессе длительных наблюдений за деревьями и древостоями. Долгосрочные эксперименты в лесном хозяйстве имеют ряд преимуществ над краткосрочными, к которым можно отнести изучение динамики показателей древостоев на протяжении больших промежутков времени, реакции древостоев на хозяйственное воздействие и изменение параметров окружающей среды. Результаты долговременных экспериментов позволили сформулировать большое количество законов роста и продуктивности древостоев, которое нашли широкое применение в мировой лесохозяйственной практике. Сохранение и развитие долговременных
экспериментов является важной задачей современного лесного хозяйства.
High CO depletion in southern infrared-dark clouds
Creators: name: Fontani, F.
name: Giannetti, A.
name: Beltran, M. T.
name: Dodson, R.
name: Rioja, M.
name: Brand, J.
name: Caselli, P.
name: Cesaroni, R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Infrared-dark high-mass clumps are among the most promising objects to study the initial conditions of the formation process of high-mass stars and rich stellar clusters. In this work, we have observed the (3-2) rotational transition of C18O with the APEX telescope, and the (1,1) and (2,2) inversion transitions of NH3 with the Australia Telescope Compact Array in 21 infrared-dark clouds already mapped in the 1.2 mm continuum, with the aim of measuring basic chemical and physical parameters such as the CO depletion factor (fD), the gas kinetic temperature and the gas mass. In particular, the C18O (3-2) line allows us to derive fD in gas at densities higher than that traced by the (1-0) and (2-1) lines, typically used in previous works. We have detected NH3 and C18O in all targets. The clumps possess mass, H2 column and surface densities consistent with being potentially the birthplace of high-mass stars. We have measured fD in between 5 and 78, with a mean value of 32 and a median of 29. These values are, to our knowledge, larger than the typical CO depletion factors measured towards infrared-dark clouds and high-mass dense cores, and are comparable to or larger than the values measured in low-mass pre-stellar cores close to the onset of the gravitational collapse. This result suggests that the earliest phases of the high-mass star and stellar cluster formation process are characterised by fD larger than in low-mass pre-stellar cores. Thirteen out of 21 clumps are undetected in the 24 μm Spitzer images, and have slightly lower kinetic temperatures, masses and H2 column densities with respect to the eight Spitzer-bright sources. This could indicate that the Spitzer-dark clumps are either less evolved or are going to form less massive objects.
description: 15 pages (without appendices), 11 figures, accepted for publication in MNRAS
title: Ethik im klinischen Alltag
Creators: name: Sela, Svea Mareike
name: Arora, Sukhdeep
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 5-14    Lernziele: Jeden Tag werden Ärzte im Klinikalltag mit ethischen Fragestellungen und Konflikten konfrontiert, die oftmals mehr als nur schulmedizinisches Wissen verlangen. Um sich schon im Medizinstudium näher mit ethischen Fragen zu beschäftigen, auf die[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Influence of randomness and retardation on the FMR-linewidth
Creators: name: Bose, Thomas
name: Trimper, Steffen
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The theory predicts that the spin-wave lifetime $τ_L$ and the linewidth of ferromagnetic resonance $ΔB$ can be governed by random fields and spatial memory. To that aim the effective field around which the magnetic moments perform a precession is superimposed by a stochastic time dependent magnetic field with finite correlation time. The magnetization dynamics is altered by inclusion of a spatial memory effect monitoring a non-local interaction of size $ξ$. The underlying Landau-Lifshitz-Gilbert equation (LLG) is modified accordingly. The stochastic LLG is equivalent to a Fokker-Planck equation which enables to calculate the mean values of the magnetization vector. Within the spin-wave approximation we present an analytical solution for the excitation energy and its damping. The lifetime and the linewidth are analyzed depending on the strength of the random field $D$ and its correlation time $τ_c$ as well as the retardation strength $Γ_0$ and the size $ξ$. Whereas $τ_L$ decreases with increasing $D$, retardation strength $Γ_0$ and $τ_c$, the lifetime is enhanced for growing width $ξ$ of the spatial retardation kernel. In the same manner we calculate the experimentally measurable linewidth $ΔB$ is increased strongly when the correlation time $τ_c$ ranges in the nanosecond interval.
description: 20 pages, 4 figures
title: Kann Humor Deinem Problem schaden?
Creators: name: Ullmann, Eva
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 5-20    Lernziele: Erleben Sie in einem unterhaltsamen und wissenschaftlich fundierten Workshop, warum Humor effektiv ist – für das Lernklima und die eigene Leistungsfähigkeit. Jeder Mensch lacht gern. Humor kann einerseits Situationen entspannen, andererseits[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Conditional detection of pure quantum states of light after storage in a waveguide
Creators: name: Saglamyurek, Erhan
name: Sinclair, Neil
name: Jin, Jeongwan
name: Slater, Joshua A.
name: Oblak, Daniel
name: Bussières, Félix
name: George, Mathew
name: Ricken, Raimund
name: Sohler, Wolfgang
name: Tittel, Wolfgang
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Conditional detection is an important tool to extract weak signals from a noisy background and is closely linked to heralding, which is an essential component of protocols for long distance quantum communication and distributed quantum information processing in quantum networks. Here we demonstrate the conditional detection of time-bin qubits after storage in and retrieval from a photon-echo based waveguide quantum memory. Each qubit is encoded into one member of a photon-pair produced via spontaneous parametric down conversion, and the conditioning is achieved by the detection of the other member of the pair. Performing projection measurements with the stored and retrieved photons onto different bases we obtain an average storage fidelity of 0.885 \pm 0.020, which exceeds the relevant classical bounds and shows the suitability of our integrated light-matter interface for future applications of quantum information processing.
description: 4 pages, 4 figures
Larsia Fittkau 1962
Creators: name: Armitage, Brian J.
name: Andersen, Trond
name: Giłka, Wojciech
name: Castillo Sánchez, Kayla N.
name: Ríos González, Tomás A.
name: Aguirre, Yusseff P.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Larsia

description: Genus Larsia Fittkau, 1962
A genus of ~30 named species that occur in all zoogeographical regions except Antarctica. Neubern & Silva (2011) described two new species from the Neotropical region and presented a checklist of the Larsia species of the world. In the Southern Hemisphere the larvae are associated with both lotic and lentic warm waters (Cranston & Epler 2013).
description: Published as part of Armitage, Brian J., Andersen, Trond, Giłka, Wojciech, Castillo Sánchez, Kayla N., Ríos González, Tomás A. & Aguirre, Yusseff P., 2025, The Diptera of Panama. II. A first benchmark for the family Chironomidae, pp. 201-240 in Zootaxa 5613 (2) on page 229, DOI: 10.11646/zootaxa.5613.2.1, http://zenodo.org/record/15224174