cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Gene therapy in an era of emerging treatment options for hemophilia B
Creators: name: Monahan, P. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Factor IX deficiency (hemophilia B) is less common than factor VIII deficiency (hemophilia A) and innovations in therapy for hemophilia B have generally lagged behind those for hemophilia A. Recently the first sustained correction of the hemophilia bleeding phenotype by clotting factor gene therapy has been described using recombinant adeno-associated virus (AAV) to deliver factor IX. Despite this success, many individuals with hemophilia B, including children, men with active hepatitis, and individuals who have pre-existing natural immunity to AAV are not eligible for the current iteration of hemophilia B gene therapy. In addition, recent advances in recombinant factor IX protein engineering have led some hemophilia treaters to reconsider the urgency of genetic cure. Current clinical and preclinical approaches to advancing AAV-based and alternative approaches to factor IX gene therapy are considered in the context of current demographics and treatment of the hemophilia B population.
AMIR TIMUR AND THE CULTURE OF THE TEMURIAN PERIOD
Creators: name: Makhmudova, Sabohat
Publisher: name: Zenodo
Year: 2023

description: Amir Temur and the period of the Timurids have a special place in the history of Central Asian culture. Cultural achievements of this period were at the level of universal civilization. The formation of Uzbek culture in this classic period in the history of culture is related to the political, socio-economic development of this period. In particular, architecture, science, literature, art, crafts flourished. Many people of science and art, artisans, architects and painters from Movarounnahr and Middle Eastern countries, India gathered for the improvement and cultural development of the country, as well as the big cities of Samarkand, Shahrisabz, Bukhara, Termiz, Tashkent and Herat. With their efforts, a group of architectural monuments in Shahizinda, Bibikhanim mosque, Dor us-siyadat (Kesh), and Ahmed Yassavi mausoleum in Turkestan were built. It is worth noting that Amir Temur and Timurids Shahrukh, Ulug'bek, Boysung'ur Mirza, Abu Said Mirza and others paid great attention to the development of culture, literature, painting, and architecture and patronized them.
(400416) Forbes Marshall Fenwick
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supporting Information from Does 1,8-diiodooctane affect the aggregation state of PC71BM in solution?.
Creators: name: Bernardo, Gabriel
name: Adam. L. Washington
name: Yiwei Zhang
name: Stephen. M. King
name: Daniel. T. W. Toolan
name: Weir, Michael P.
name: Dunbar, Alan D. F.
name: Howse, Jonathan R.
name: Dattani, Rajeev
name: Fairclough, John Patrick A.
name: Parnell, Andrew J.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering
subject: 30699 Physical Chemistry not elsewhere classified
subject: FOS: Chemical sciences
subject: 100799 Nanotechnology not elsewhere classified
subject: FOS: Nanotechnology

description: 1,8-Diiodooctane (DIO) is an additive used in the processing of organic photovoltaics and has previously been reported, on the basis of small-angle X-ray scattering (SAXS) measurements, to deflocculate nano-aggregates of [6,6]-phenyl-C71-butyric acid methyl ester (PC71BM) in chlorobenzene. We have critically re-examined this finding in a series of scattering measurements using both X-rays and neutrons. With SAXS, we find that the form of the background solvent scattering is influenced by the presence of DIO, that there is substantial attenuation of the X-rays by the background solvent and that there appears to be beam-induced aggregation. All three factors call into question the suitability of SAXS for measurements on these samples. By contrast, SANS measurements, performed at concentrations of 15 mg ml−1 up to and including 40 mg ml−1, show no difference in the aggregation state for PC71BM in chlorobenzene with and without 3% DIO; we find PC71BM to be molecularly dissolved in all solvent cases. In situ measurements of spin-coated PC71BM with the DIO additive dry much slower. Optical imaging shows that the fullerene films possess enhanced molecular mobility in the presence of DIO and it is this which, we conclude, improves the nanomorphology and consequently solar cell performance. We propose that any compatible high boiling solvent would be expected to show the same behaviour.
(400411) John Fenwick
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Novel mouse hemostasis model for real-time determination of bleeding time and hemostatic plug composition
Creators: name: Bergmeier, W.
name: Monroe, D.
name: Mackman, N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Hemostasis is a rapid response by the body to stop bleeding at sites of vessel injury. Both platelets and fibrin are important for the formation of a hemostatic plug. Mice have been used to uncover the molecular mechanisms that regulate the activation of platelets and coagulation under physiologic conditions. However, measurements of hemostasis in mice are quite variable, and current methods do not quantify platelet adhesion or fibrin formation at the site of injury.
Prospective study of sickle cell trait and venous thromboembolism incidence
Creators: name: Kshirsagar, A. V.
name: Folsom, A. R.
name: Tang, W.
name: Roetker, N. S.
name: Derebail, V. K.
name: Grove, M. L.
name: Key, N. S.
name: Lutsey, P. L.
name: Basu, S.
name: Cushman, M.
name: Pankow, J. S.
name: Naik, R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Sickle cell trait may increase risk of venous thromboembolism, but this is not fully established.
Generation of platicons and frequency combs in optical microresonators with normal GVD by modulated pump
Creators: name: Lobanov, Valery E.
name: Lihachev, Grigory
name: Gorodetsky, Michael L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We demonstrate that flat-topped dissipative solitonic pulses, platicons, and corresponding frequency combs can be excited in optical microresonators with normal group velocity dispersion using either amplitude modulation of the pump or bichromatic pump. Soft excitation may occur in particular frequency range if modulation depth is large enough and modulation frequency is close to the free spectral range of the microresonator.
description: 10 pages, 4 figures, to appear in EPL
(400412) Margaret Fenwick
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supporting Information from Does 1,8-diodooctane affect the aggregation state of PC71BM in solution?
Creators: name: Bernardo, Gabriel
name: Adam. L. Washington
name: Yiwei Zhang
name: Stephen. M. King
name: Daniel. T. W. Toolan
name: Weir, Michael P.
name: Dunbar, Alan D. F.
name: Howse, Jonathan R.
name: Dattani, Rajeev
name: Fairclough, John Patrick A.
name: Parnell, Andrew J.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering
subject: 30699 Physical Chemistry not elsewhere classified
subject: FOS: Chemical sciences
subject: 100799 Nanotechnology not elsewhere classified
subject: FOS: Nanotechnology

description: 1,8-Diiodooctane (DIO) is an additive used in the processing of organic photovoltaics and has previously been reported, on the basis of small-angle X-ray scattering (SAXS) measurements, to deflocculate nano-aggregates of [6,6]-phenyl-C71-butyric acid methyl ester (PC71BM) in chlorobenzene. We have critically re-examined this finding in a series of scattering measurements using both X-rays and neutrons. With SAXS, we find that the form of the background solvent scattering is influenced by the presence of DIO, that there is substantial attenuation of the X-rays by the background solvent and that there appears to be beam-induced aggregation. All three factors call into question the suitability of SAXS for measurements on these samples. By contrast, SANS measurements, performed at concentrations of 15 mg ml−1 up to and including 40 mg ml−1, show no difference in the aggregation state for PC71BM in chlorobenzene with and without 3% DIO; we find PC71BM to be molecularly dissolved in all solvent cases. In situ measurements of spin-coated PC71BM with the DIO additive dry much slower. Optical imaging shows that the fullerene films possess enhanced molecular mobility in the presence of DIO and it is this which, we conclude, improves the nanomorphology and consequently solar cell performance. We propose that any compatible high boiling solvent would be expected to show the same behaviour.
Pressure tuning domain-wall chirality in noncentrosymmetric magnetic Weyl semimetal CeAlGe
Creators: name: He, Xiaobo
name: Li, Yuke
name: Zeng, Hai
name: Zhu, Zengwei
name: Tan, Shiyong
name: Zhang, Yongjun
name: Cao, Chao
name: Luo, Yongkang
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Topological magnetic Weyl semimetals have been proposed to host controllable chiral domain walls which bear a great prospect in device applications. To exploit them in applications, it is important to have a proper way to tune and manipulate these domain walls. One possible means is through magnetoelastic coupling. The involvement of rare earth in the lately proposed $R$Al$X$ ($R$=rare earth, $X$=Si and Ge) family magnetic Weyl semimetals may provide such a platform. Here we present transport and thermodynamic properties of CeAlGe under hydrostatic pressure. We find that pressure enhances the antiferromagnetic exchange in CeAlGe but essentially retains its magnetic structure. Large topological Hall effect with pronounced loop shape is observed within the magnetically ordered state, and it splits into two regions under pressure. Such an unusual electromagnetic response is inferred to be a consequence of chiral magnetic domain walls. The unprecedented concomitance of its evolution under pressure and the reentrance of antiferromagnetic order strongly suggest the capability of switching on/off this electromagnetic response in noncentrosymmetric magnetic Weyl semimetals via magnetoelastic coupling.
description: 20+3 pages, 5+3 figures, 1 table
Venous thrombosis and cancer: from mouse models to clinical trials
Creators: name: Ay, C.
name: Mackman, N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Cancer patients have a ~4 fold increased risk of venous thromboembolism (VTE) compared with the general population and this is associated with significant morbidity and mortality. This review summarizes our current knowledge of VTE and cancer from mouse models to clinical studies. Notably, risk of VTE varies depending on the type and stage of cancer. For instance, pancreatic and brain cancer patients have a higher risk of VTE than breast and prostate cancer patients. Moreover, patients with metastatic disease have a higher risk than those with localized tumors. Tumor-derived procoagulant factors and growth factors may directly and indirectly enhance VTE. For example, increased levels of circulating tumor-derived, tissue factor-positive microvesicles may trigger VTE. In a mouse model of ovarian cancer, tumor-derived IL-6 and hepatic thrombopoietin has been linked to increased platelet production and thrombosis. In addition, mouse models of mammary and lung cancer showed that tumor-derived granulocyte colony-stimulating factor causes neutrophilia and activation of neutrophils. Activated neutrophils can release neutrophil extracellular traps (NETs) that enhance thrombosis. Cell-free DNA in the blood derived from cancer cells, NETs and treatment with cytotoxic drugs can activate the clotting cascade. These studies suggest that there are multiple mechanisms for VTE in patients with different types of cancer. Preventing and treating VTE in cancer patients is challenging; the current recommendations are to use low molecular weight heparin. Understanding the underlying mechanisms may allow the development of new therapies to safely prevent VTE in cancer patients.
(400413) Robert Fenwick
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Extension theory approach in the stability of the standing waves for the NLS equation with point interactions on a star graph
Creators: name: Pava, Jaime Angulo
name: Goloshchapova, Nataliia
Publisher: name: arXiv
Year: 2015
Subjects: subject: Spectral Theory (math.SP)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q55, 81Q35, 37K40, 37K45, 47E05

description: The aim of this work is to demonstrate the effectiveness of the extension theory of symmetric operators in the investigation of the stability of standing waves for the nonlinear Schrödinger equations with two types of non-linearities (power and logarithmic) and two types of point interactions ($δ$- and $δ'$-) on a star graph. Our approach allows us to overcome the use of variational techniques in the investigation of the Morse index for self-adjoint operators with non-standard boundary conditions which appear in the stability study. We also demonstrate how our method simplifies the proof of the stability results known for the NLS equation with point interactions on the line.
description: 44 pages
title:  Cassazione e legalità penale
Creators: name: Canzio, Giovanni
Publisher: name: Roma TrE-Press
Year: 2016

description: La Magistratura - istituzione della ragione, sottratta alla logica del consenso popolare perché prevalgano solo le esigenze di giustizia e di tutela dei diritti della persona – è chiamata oggi a interrogarsi sulla moderna declinazione del principio costituzionale di esclusiva soggezione del giudice alla legge, cui è ancorato il fondamento dell’indipendenza e dell’autonomia.
description: Scritti dedicati a Maurizio Converso
Intra-city Differences in Cardiac Expression of Inflammatory Genes and Inflammasomes in Young Urbanites: A Pilot Study
Creators: name: Villarreal-Calderon, Rodolfo
name: Calderón-Garcidueñas, Lilian
name: Zhu, Hongtu
name: Medina-Cortina, Humberto
name: Delgado-Chávez, Ricardo
name: Yuan, Ying
name: Solorio-López, Edelmira
name: Gónzalez-Maciel, Angelica
name: Dale, Gary
name: Wang, Jiaping
name: Torres-Jardón, Ricardo
name: Herritt, Lou
name: Reynoso-Robles, Rafael
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Southwest Mexico City (SWMC) air pollution is characterized by high concentrations of ozone and particulate matter < 10 μm (PM10) containing lipopolysaccharides while in the North PM2.5 is high. These intra-city differences are likely accounting for higher CD14 and IL-1β in SWMC v NMC mice myocardial expression. This pilot study was designed to investigate whether similar intra-city differences exist in the levels of myocardial inflammatory genes in young people. Inflammatory mediator genes and inflammasome arrays were measured in right and left autopsy ventricles of 6 southwest/15 north (18.5 ± 2.6 years) MC residents after fatal sudden accidental deaths. There was a significant S v N right ventricle up-regulation of IL-1β (p=0.008), TNF-α (p=0.001), IL-10 (p=0.001), and CD14 (p=0.002), and a left ventricle difference in TNF-α (p=0.007), and IL-10 (p=0.02). SW right ventricles had significant up-regulation of NLRC1, NLRP3 and of 29/84 inflammasome genes, including NOD factors and caspases. There was significant degranulation of mast cells both in myocardium and epicardial nerve fibers. Differential expression of key inflammatory myocardial genes and inflammasomes are influenced by the location of residence. Myocardial inflammation and inflammasome activation in young hearts is a plausible pathway of heart injury in urbanites and adverse effects on the cardiovascular system are expected.
(400408) William Parrott Ingrams
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Procoagulant Microparticles in Dogs with Immune-Mediated Hemolytic Anemia
Creators: name: Nichols, T.
name: Geddings, J.
name: Merricks, E.
name: Concannon, T.
name: Hisada, Y.
name: Kidd, L.
name: Mackman, N.
name: Sueda, M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: BACKGROUND: Studies of some human prothrombotic diseases suggest that phosphatidylserine-positive (PS+) and tissue factor-positive (TF+) microparticles (MPs) might play a role in the pathogenesis of thrombosis or serve as biomarkers of thrombotic risk.

HYPOTHESIS/OBJECTIVES: To determine if circulating levels of PS+MP and procoagulant activity (PCA) associated with PS+MPs and TF+ MPs are increased in dogs with IMHA.

ANIMALS: Fifteen dogs with primary or secondary IMHA and 17 clinically healthy dogs.

METHODS: Prospective case-controlled observational study. Circulating PS+MPs were measured by flow cytometry. PCA associated with PS+MPs and TF+MPs was measured by thrombin and Factor Xa generating assays, respectively.

RESULTS: Circulating numbers of PS+MPs were not significantly higher in dogs with IMHA [control median 251,000/μL (36,992-1,141,250/μL); IMHA median 361,990/μL (21,766-47,650,600/μL) P = .30]. However, PS+MP PCA [control median 2.2 (0.0-16.8) nM PS eq; IMHA median 8.596, (0-49.33 nM PS eq) P = .01] and TF+MP PCA [control median 0.0, (0.0-0.0 pg/mL); IMHA median 0.0; (0-22.34 pg/mL], P = .04) were increased. Intravascular hemolysis, which we showed might increase PS+ and TF+MP PCA, was evident in 3 of 5 dogs with PS+MP PCA and 2 of 4 dogs with TF+MP PCA higher than controls. Underlying disease in addition to IMHA was detected in 1 of 5 dogs with PS+PCA and 3 of 4 dogs with TF+MP PCA higher than controls.

CONCLUSIONS AND CLINICAL IMPORTANCE: TF+ and PS+MP PCA is increased in some dogs with IMHA. Further studies that determine if measuring TF+ and PS+ MP PCA can help identify dogs at risk for thrombosis are warranted.
Facial Expression Cloning with Elastic and Muscle Models
Creators: name: Zhang, Yihao
name: Lin, Weiyao
name: Zhou, Bing
name: Chen, Zhenzhong
name: Sheng, Bin
name: Wu, Jianxin
name: Zhang, Wenjun
Publisher: name: arXiv
Year: 2015
Subjects: subject: Graphics (cs.GR)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: Expression cloning plays an important role in facial expression synthesis. In this paper, a novel algorithm is proposed for facial expression cloning. The proposed algorithm first introduces a new elastic model to balance the global and local warping effects, such that the impacts from facial feature diversity among people can be minimized, and thus more effective geometric warping results can be achieved. Furthermore, a muscle-distribution-based (MD) model is proposed, which utilizes the muscle distribution of the human face and results in more accurate facial illumination details. In addition, we also propose a new distance-based metric to automatically select the optimal parameters such that the global and local warping effects in the elastic model can be suitably balanced. Experimental results show that our proposed algorithm outperforms the existing methods.
description: This manuscript is the accepted version for JVCI (Journal of Visual Communication and Image Representation)
Adherence to PEG/ribavirin treatment for chronic hepatitis C: prevalence, patterns, and predictors of missed doses and nonpersistence
Creators: name: Evon, D. M.
name: Golin, C. E.
name: Rao, T.
name: Esserman, D. A.
name: Fried, M. W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Adherence to treatment for hepatitis C virus (HCV) maximizes treatment efficacy. Missed doses and failing to persist on treatment are two patient-level processes that are rarely defined or analyzed separately from other factors affecting treatment adherence. We evaluated the prevalence and patterns of missed doses and nonpersistence, and identified patient characteristics associated with these outcomes. Missed doses of ribavirin (RBV) and peginterferon (PEG), measured prospectively in Virahep-C using electronic monitoring technology, were analyzed using generalized estimating equations. Cox proportional hazards models analyzed time to nonpersistence from baseline to week 24 (N=401) and from week 24–48 in Responders (N=242). Average proportion of PEG and RBV missed doses increased over time from 5 to 15% and 7 to 27%, respectively. Patients who were younger, African American, unemployed, or unmarried were at greater risk of missing PEG from week 0–24; higher baseline depression predicted missing PEG from weeks 24–48. Patients who were younger or African American were more likely to miss daily RBV from weeks 0–24; and those without private insurance or employment were more likely to miss RBV from weeks 24–48. Fifty-two patients failed to persist on treatment for patient-driven deviations. Predictors of nonpersistence from weeks 0–24 included younger age, lower education, public or no insurance, or worse baseline headaches. In conclusion electronic monitoring and the prospective Virahep-C design afforded a unique opportunity to evaluate missing doses and nonpersistence separately, and identify patients at risk for nonadherence. These processes will be important to investigate as the dosing schedules of antiviral regimens become increasingly complex.
Highlights of the 2012 Research Workshop: Using Nutrigenomics and Metabolomics in Clinical Nutrition Research
Creators: name: Fodor, Anthony
name: Ordovás, José M.
name: Jia, Wei
name: Muoio, Deborah M.
name: Waterland, Robert A.
name: Zeisel, Steven H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: No Abstract.
Disordered aldosterone-volume relationship in end-stage kidney disease
Creators: name: Bomback, Andrew S
name: Kshirsagar, Abhijit V
name: Ferris, Maria E
name: Klemmer, Philip J
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Sodium loading, and subsequent volume expansion, suppresses aldosterone levels in individuals with normal renal function. We hypothesised that loss of renal function impairs this volume-aldosterone relationship.
Supplementary Methods and Figures from Stratigraphic signatures of mass extinctions: ecological and sedimentary determinants.
Creators: name: Rafał Nawrot
name: Scarponi, Daniele
name: Azzarone, Michele
name: Dexter, Troy A.
name: Kusnerik, Kristopher M.
name: Wittmer, Jacalyn M.
name: Amorosi, Alessandro
name: Michał Kowalewski
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Details of the geological setting, resampling models and statistical analyses. Supplementary figures S1–S9.
Phase-control of bipolar thermoelectricity in Josephson tunnel junctions
Creators: name: Germanese, Gaia
name: Paolucci, Federico
name: Marchegiani, Giampiero
name: Braggio, Alessandro
name: Giazotto, Francesco
Publisher: name: arXiv
Year: 2022
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Not so long ago, thermoelectricity in superconductors was believed to be possible only by breaking explicitly the particle-hole symmetry. Recently, it has been theoretically predicted that a superconducting tunnel junction can develop bipolar thermoelectric phenomena in the presence of a large thermal gradient owing to non-equilibrium spontaneous PH symmetry breaking. The experimental realization of the first thermoelectric Josephson engine then followed. Here, we give a more extended discussion and focus on the impact of the Josephson contribution on thermoelectricity modulating the Cooper pairs transport in a double-loop SQUID. When the Cooper pairs current prevails on the quasiparticle one, the Josephson contribution short-circuits the junction thereby screening the thermoelectric effect. We demonstrate that the thermoelectric generation due to the pure quasiparticle transport is phase-independent, once Josephson contribution is appropriately removed from the net current measured. At the same time, we investigate an additional metastable state at V\simeq0 determined by the presence of the Josephson coupling, which peculiarly modifies the hysteretic behavior of our thermoelectric engine realized. At the end, we also discuss how the current-voltage characteristics are affected by the presence of multiple thermoelectric elements, which improve the generated output power.
description: 16 pages, 11 figures
Cardiodynamics and Infarct Size in Regional and Global Ischemic Isolated Heart Model: Comparison of 1 Hour and 2 Hours Reperfusion
Creators: name: Jang, Young Ho
name: Kim, Jun
name: Xu, Zhelong
name: Chun, Kook Jin
name: Park, Yong Hyun
name: Kim, Jeong Su
name: Lee, Mi Young
name: Kim, June Hong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Background and ObjectivesWe investigated whether 1 hour reperfusion is enough to assess cardiodynamics and infarct size in both regional ischemia (RI) and global ischemia (GI) in isolated rat heart models.Materials and MethodsHearts were randomly assigned to one of the following groups (each n=14): 1) Sham hearts for 1 hour; 2) Sham hearts for 2 hours; 3) 30 minutes RI followed by 1 hour reperfusion; 4) 30 minutes of RI followed by 2 hours reperfusion; 5) 30 minutes GI followed by 1 hour reperfusion; and 6) 30 minutes GI followed by 2 hours reperfusion.ResultsThere were no significant differences in infarct size between 1 hour and 2 hours reperfusion in both RI and GI. Left ventricular developed pressure was significantly decreased at both 1 hour and 2 hours reperfusion in groups of RI and GI compared to baseline (p<0.01). Rate-pressure product and +dP/dtmax also significantly decreased compared to baseline level at both 1 hour and 2 hours reperfusion in groups of RI and GI (p<0.05).ConclusionThere was no significant difference in infarct size between 1 hour and 2 hours reperfusion in groups of RI and GI. Cardiodynamic variables measured at 1 hour and 2 hours reperfusion significantly decreased compared to baseline level. Our data suggests that reperfusion of 1 hour is sufficient to assess cardiodynamics in both regional and global ischemic isolated hearts model.
Systematic bias on the inspiral-merger-ringdown consistency test due to neglect of orbital eccentricity
Creators: name: Bhat, Sajad A.
name: Saini, Pankaj
name: Favata, Marc
name: Arun, K. G.
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The inspiral-merger-ringdown (IMR) consistency test checks the consistency of the final mass and final spin of a binary black hole merger remnant, independently inferred via the inspiral and merger-ringdown parts of the waveform. As binaries are expected to be nearly circularized when entering the frequency band of ground-based detectors, tests of general relativity (GR) currently employ quasicircular waveforms. We quantify the effect of residual orbital eccentricity on the IMR consistency test. We find that eccentricity causes a significant systematic bias in the inferred final mass and spin of the remnant black hole at an orbital eccentricity (defined at $10$ Hz) of $e_0 \gtrsim 0.1$ in the LIGO band (for a total binary mass in the range $65$-$200 \,M_{\odot}$). For binary black holes observed by Cosmic Explorer (CE), the systematic bias becomes significant for $e_0 \gtrsim 0.015$ (for $200$-$600 \,M_{\odot}$ systems). This eccentricity-induced bias on the final mass and spin leads to an apparent inconsistency in the IMR consistency test, manifesting as a false violation of GR. Hence, eccentric corrections to waveform models are important for constructing a robust test of GR, especially for third-generation detectors. We also estimate the eccentric corrections to the relationship between the inspiral parameters and the final mass and final spin; they are shown to be quite small.
description: 15 pages, 16 Figures, published in Phys. Rev. D. v2: minor changes to match the published version
(400409) John Fenwick
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Invasive Micropapillary Carcinoma of the Breast: MR Imaging Findings
Creators: name: Kim, Jin Woong
name: Kuzmiak, Cherie M.
name: Park, Min Ho
name: Jeong, Seo In
name: Lee, Ji Shin
name: Choi, You Ri
name: Lim, Hyo Soon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: ObjectiveTo analyze the magnetic resonance (MR) imaging findings of invasive micropapillary carcinoma of the breast.Materials and MethodsMR images were retrospectively evaluated in 14 patients (age range: 37-67, mean age: 49 years) with pathologically confirmed invasive micropapillary carcinoma of the breast. The enhancement type (mass/non-mass), shape, margin, contrast enhancement, and time-intensity curve pattern on the dynamic study were correlated with the histopathologic features. Associated findings, such as edema, nipple change, skin change and enlarged axillary lymph nodes were also studied.ResultsThe most common features of the masses were irregular shape (12 of 14 patients, 85.8%) and irregular or spiculated margin (11 of 14 patients, 78.7%). The contrast enhancement was heterogeneous in 11 patients (78.7%), rim enhancement in 2 cases (14.2%), and homogeneous in one patient (7.1%). The predominant kinetic pattern was rapid increase (14 of 14, 100%) in the initial phase and washout (11 of 14, 78.7%) in the delayed phase. Associated non-mass like enhancement was shown in 4 patients, representing ductal carcinoma in situ. MR imaging helped detect additional sites of cancer other than the index lesion in 3 patients (21.4%). Enlarged axillary lymphadenopathy was identified in 7 of the 14 patients (50%).ConclusionInvasive micropapillary carcinoma appears as a mass with an irregular shape, irregular or spiculated margin and heterogeneous enhancement on MR imaging. Though these findings are not specific and are also observed with other breast malignancies, invasive micropapillary carcinoma frequently showed multiple lesions, accompanying non-mass enhancement and axillary lymph node enlargement.
Improved Image Deblurring based on Salient-region Segmentation
Creators: name: Zhang, Chongyang
name: Lin, Weiyao
name: Li, Wei
name: Zhou, Bing
name: Xie, Jun
name: Li, Jijia
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Image deblurring techniques play important roles in many image processing applications. As the blur varies spatially across the image plane, it calls for robust and effective methods to deal with the spatially-variant blur problem. In this paper, a Saliency-based Deblurring (SD) approach is proposed based on the saliency detection for salient-region segmentation and a corresponding compensate method for image deblurring. We also propose a PDE-based deblurring method which introduces an anisotropic Partial Differential Equation (PDE) model for latent image prediction and employs an adaptive optimization model in the kernel estimation and deconvolution steps. Experimental results demonstrate the effectiveness of the proposed algorithm.
description: This manuscript is the accepted version for Image Comm (Signal Processing: Image Communication)
Supplementary Methods and Figures from Stratigraphic signatures of mass extinctions: ecological and sedimentary determinants
Creators: name: Rafał Nawrot
name: Scarponi, Daniele
name: Azzarone, Michele
name: Dexter, Troy A.
name: Kusnerik, Kristopher M.
name: Wittmer, Jacalyn M.
name: Amorosi, Alessandro
name: Michał Kowalewski
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Details of the geological setting, resampling models and statistical analyses. Supplementary figures S1–S9.
Dilution of dark matter relic density in singlet extension models
Creators: name: Xiao, Yang
name: Yang, Jin Min
name: Zhang, Yang
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We study the dilution of dark matter (DM) relic density caused by the electroweak first-order phase transition (FOPT) in the singlet extension models, including the singlet extension of the standard model (xSM), of the two-Higgs-doublet model (2HDM+S) and the next-to-minimal supersymmetric standard model (NMSSM). We find that in these models the entropy released by the strong electroweak FOPT can dilute the DM density to 1/3 at most. Nevertheless, in the xSM and NMSSM where the singlet field configure is relevant to the phase transition temperature, the strong FOPT always happens before the DM freeze-out, making the dilution effect negligible for the current DM density. On the other hand, in the 2HDM+S where the DM freeze-out temperature is independent of FOPT, the dilution may salvage some parameter space excluded by excessive DM relic density or by DM direct detections.
description: 21 pages, 7 figures;version accepted for publication in JHEP
Supplementary material from Drought-induced Amazonian wildfires instigate a decadal-scale disruption of forest carbon dynamics.
Creators: name: Silva, Camila V. J.
name: Luiz E. O. C. Aragão
name: Barlow, Jos
name: Espirito-Santo, Fernando
name: Young, Paul J.
name: Anderson, Liana O.
name: Berenguer, Erika
name: Izaias Brasil
name: I. Foster Brown
name: Castro, Bruno
name: Farias, Renato
name: Ferreira, Joice
name: França, Filipe
name: Graça, Paulo M. L. A.
name: Kirsten, Letícia
name: Lopes, Aline
name: Cleber Salimon
name: Scaranello, Marcos
name: Seixas, Marina
name: Souza, Fernanda
name: Haron Xaud
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology

description: Method S1: Description of methods applied for MCWD and Burned Area anomaly calculations in figure 1; Tables S1-S4; Figures S1-S3
High process yield rates of thermoplastic nanofluidic devices using a hybrid thermal assembly technique
Creators: name: Weerakoon-Ratnayake, Kumuditha
name: Soper, Steven A.
name: Hu, Bo
name: Uba, Franklin I.
name: Oliver-Calixte, Nyote
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: A low temperature hybrid assembly process for the production of functional thermoplastic nanofluidic devices with process yield rates >90% and an assembly time of 16 min is reported.
Experimental Conditions for Determination of the Neutrino Mass Hierarchy with Reactor Antineutrinos
Creators: name: Pac, M. Y.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: This article reports the optimized experimental requirements to determine neutrino mass hierarchy using electron antineutrinos ($\barν_e$) generated in a nuclear reactor. The features of the neutrino mass hierarchy can be extracted from the $|Δm^{2}_{31}|$ and $|Δm^{2}_{32}|$ oscillations by applying the Fourier sine and cosine transform to the $L/E$ spectrum. To determine the neutrino mass hierarchy above 90\% probability, the requirements on the energy resolution as a function of the baseline are studied at $\sin 2θ_{13}=0.1$. If the energy resolution of the neutrino detector is less than $0.04/ \sqrt{E_ν}$ and the determination probability obtained from Bayes' theorem is above 90\%, the detector needs to be located around 48--53 km from the reactor(s) to measure the energy spectrum of $\barν_e$. These results will be helpful for setting up an experiment to determine the neutrino mass hierarchy, which is an important problem in neutrino physics.
(400410) Margaret Potts [Pottie]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Optimal Solutions to Relaxation in Multiple Control Problems of Sobolev Type with Nonlocal Nonlinear Fractional Differential Equations
Creators: name: Debbouche, Amar
name: Nieto, Juan J.
name: Torres, Delfim F. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 26A33, 34B10, 49J15, 49J45

description: We introduce the optimality question to the relaxation in multiple control problems described by Sobolev type nonlinear fractional differential equations with nonlocal control conditions in Banach spaces. Moreover, we consider the minimization problem of multi-integral functionals, with integrands that are not convex in the controls, of control systems with mixed nonconvex constraints on the controls. We prove, under appropriate conditions, that the relaxation problem admits optimal solutions. Furthermore, we show that those optimal solutions are in fact limits of minimizing sequences of systems with respect to the trajectory, multi-controls, and the functional in suitable topologies.
description: This is a preprint of a paper whose final and definite form will be published in Journal of Optimization Theory and Applications, ISSN 0022-3239 (print), ISSN 1573-2878 (electronic). Submitted: 26-Dec-2014; Revised: 14-Apr-2015; Accepted: 19-Apr-2015
Refined Lattice Path Enumeration and Combinatorial Reciprocity
Creators: name: Mühle, Henri
name: Tzanaki, Eleni
Publisher: name: arXiv
Year: 2022
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05A15, 05A19

description: It is well known that the set of $m$-Dyck paths with a fixed height and a fixed amount of valleys is counted by the Fuß-Narayana numbers. In this article, we consider the set of $m$-Dyck paths that start with at least $t$ north steps. We give exact formulas for the number of such paths with fixed height, fixed number of returns and (i) fixed number of valleys, (ii) fixed number of valleys with $x$-coordinate divisible by $m$ and (iii) fixed number of valleys with $x$-coordinate not divisible by $m$. The enumeration (ii) combinatorially realizes the $H$-triangle appearing in a recent article of Krattenthaler and the first author (Algebr. Comb. 5, 2022) in the context of certain parabolic noncrossing partitions. Through a transformation formula due to Chapoton, we give an explicit formula for the associated $F$-triangle. We realize this polynomial combinatorially by means of generalized Schröder paths as well as flats in certain hyperplane arrangements. Along the way we exhibit two new combinatorial reciprocity results.
description: 44 pages, 9 figures. Comments are very welcome
LAND MANAGEMENT POLICY AND ITS IMPLEMENTATION IN ADDIS ABABA CITY GOVERNMENT:-THE CASE OF ARADA AND YEKA SUB CITIES
Creators: name: Tariku Eticha
Publisher: name: Zenodo
Year: 2017

description: Land markets contribute directly to economic growth through capital

formation. In this regard, land developers have a crucial role to play, in that

they develop sites generating higher values, making it possible for urban land

markets to contribute significantly to capital formation direction. The most

important function of land markets in economic growth is moving land from the

inefficient user to the more efficient one. The past two decades of public

ownership of land and centralization of some of the land related activities have

proved the public sector’s inefficiency, sluggishness and bureaucratic land

allocation that didn’t cope with the fast growing demand of the population, only

contributing to land price escalation and corruption in the city and in the

studied area
Micro-elastometry on whole blood clots using actuated surface-attached posts (ASAPs)
Creators: name: Spero, Richard Chasen
name: Oberhardt, Bruce
name: Fiser, Briana L.
name: Judith, Robert M.
name: Taylor, R. M.
name: Fisher, Jay K.
name: Turner, Adam
name: Falvo, Michael R.
name: Superfine, Richard
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: We used magnetically actuatable micro-post arrays to measure blood clot elasticity for blood clotting diagnostics.
Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients
Creators: name: Taylor, A. M.
name: Gupton, S. L.
name: Menon, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: A user-friendly microfluidic chamber produces a passive, stable gradient of soluble cues for imaging and quantification of axon turning.
Continuity of the quantum Fisher information
Creators: name: Rezakhani, A. T.
name: Hassani, M.
name: Alipour, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In estimating an unknown parameter of a quantum state the quantum Fisher information (QFI) is a pivotal quantity, which depends on the state and its derivate with respect to the unknown parameter. We prove the continuity property for the QFI in the sense that two close states with close first derivatives have close QFIs. This property is completely general and irrespective of dynamics or how states acquire their parameter dependence and also the form of parameter dependence---indeed this continuity is basically a feature of the classical Fisher information that in the case of the QFI naturally carries over from the manifold of probability distributions onto the manifold of density matrices. We demonstrate that in the special case where the dependence of the states on the unknown parameter comes from one dynamical map (quantum channel), the continuity holds in its reduced form with respect to the initial states. In addition, we show that when one initial state evolves through two different quantum channels, the continuity relation applies in its general form. A situation in which such scenario can occur is an open-system metrology where one of the maps represents the ideal dynamics whereas the other map represents the real (noisy) dynamics. In the making of our main result, we also introduce a regularized representation for the symmetric logarithmic derivative which works for general states even with incomplete rank, and its features continuity similarly to the QFI.
description: 16 pages