Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis
Creators: name: Cain, Jason
name: Ahsan, Sama
name: Van Meir, Erwin G.
name: Guzman, Miguel
name: Rao, Amulya A. Nageswara
name: Tabori, Uri
name: Giannini, Caterina
name: Metellus, Phillipe
name: Soto, Horacio
name: Dirks, Peter
name: Wheeler, Helen
name: Colman, Howard
name: Merchant, Thomas E.
name: Pfister, Stefan M.
name: Kool, Marcel
name: Soffietti, Riccardo
name: Alonso, Marta M.
name: Fouladi, Maryam
name: Giangaspero, Felice
name: Oba-Shinjo, Sueli M.
name: Ramaswamy, Vijay
name: Shalaby, Tarek
name: Faria, Claudia C.
name: Bartels, Ute
name: Hortobágyi, Tibor
name: Tirapelli, Daniela P.C.
name: Yong, William H.
name: Pajtler, Kristian W.
name: Chambless, Lola B.
name: Korshunov, Andrey
name: Wani, Khalida
name: Luu, Betty
name: Lassaletta, Alvaro
name: Massimi, Luca
name: Lin, Tong
name: Vera-Bolanos, Elizabeth
name: Goldman, Stewart
name: Dhall, Girish
name: Ladha, Harshad
name: Massimino, Maura
name: Liau, Linda M.
name: Fan, Xing
name: Ellison, David W.
name: Jones, David T.W.
name: Aldape, Kenneth
name: McLendon, Roger E.
name: Emery, Lyndsey
name: Chan, Jennifer A.
name: Gardner, Corrine
name: Olson, James M.
name: Gururangan, Sridharan
name: Fulton, Dorcas
name: Zagzag, David
name: Hamilton, Ronald L.
name: Robins, H. Ian
name: Grossbach, Andrew
name: Eisenstat, David D.
name: Omuro, Antonio M.
name: Lipp, Eric S.
name: Packer, Roger J.
name: Gilbert, Mark R.
name: Schüller, Ulrich
name: Zitterbart, Karel
name: Jung, Shin
name: Tuñon, Teresa
name: Dunham, Christopher
name: Mack, Stephen C.
name: Cavalli, Florence M.G.
name: Mynarek, Martin
name: Ermoian, Ralph P.
name: Leary, Sarah
name: Hawkins, Cynthia E.
name: Armstrong, Terri S.
name: Osuka, Satoru
name: Carlotti, Carlos G.
name: Klekner, Almos
name: Leonard, Jeffrey R.
name: Hauser, Peter
name: Zollo, Massimo
name: Marie, Suely K.N.
name: Van Veelen, Marie-Lise C.
name: Bouffet, Eric
name: Rutka, James T.
name: Sterba, Jaroslav
name: Mora, Jaume
name: Grotzer, Michael
name: Fisher, Paul G.
name: Cinalli, Giuseppe
name: Nunes, Sofia
name: Lieberman, Frank
name: Hukin, Juliette
name: Everson, Richard
name: Pollack, Ian F.
name: Grajkowska, Wieslawa A.
name: Santi, Mariarita
name: Lee, Ji Yeoun
name: Elbabaa, Samer K.
name: Taylor, Michael D.
name: Remke, Marc
name: Mikkelsen, Tom
name: Van Landeghem, Frank K.H.
name: Karajannis, Matthias A.
name: Hwang, Eugene
name: Rutkowski, Stefan
name: Von Hoff, Katja
name: Eberhart, Charles G.
name: Muraszko, Karin M.
name: Prados, Michael
name: Bognár, László
name: Jabado, Nada
name: Gajjar, Amar
name: Buttarelli, Francesca R.
name: Hielscher, Thomas
name: Wu, Jing
name: Petrecca, Kevin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Posterior fossa ependymoma comprises two distinct molecular variants termed EPN_PFA and EPN_PFB that have a distinct biology and natural history. The therapeutic value of cytoreductive surgery and radiation therapy for posterior fossa ependymoma after accounting for molecular subgroup is not known.