cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Conceptual PlayWorlds in Family Settings: Creating Conditions for Children’s STEM Concept Formation
Creators: name: Nedovic, Sonya
Publisher: name: Monash University
Year: 2025
Subjects: classificationCode: 390302
subject: Early childhood education

description: Fleer’s Conceptual PlayWorld model was used as an intervention into family practice to examine how parents of toddlers and pre-schoolers can create motivating conditions for STEM learning. This model is based on the notion that imagination is strongly associated with children’s conceptual development and that adults can support STEM learning by entering imaginary play scenarios in meaningful ways. The study found that parents initiated new ‘agentic’ practices including participation in imaginary play and the intentional introduction of conceptual information. This, in turn, supported children’s STEM learning.
sj-docx-4-sgo-10.1177_21582440221145914 – Supplemental material for Students as Co-Creators: Bringing Culturally Responsive Teaching into a Doctoral Course for International Students in China
Creators: name: Androsov, Alexey
name: Zhang, BaoHui
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: 160299 Criminology not elsewhere classified
subject: FOS: Law
subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-4-sgo-10.1177_21582440221145914 for Students as Co-Creators: Bringing Culturally Responsive Teaching into a Doctoral Course for International Students in China by Alexey Androsov and BaoHui Zhang in SAGE Open
Physiological and pathophysiological changes following sleeve gastrectomy
Creators: name: SHAH, YAZMIN BINTI JOHARI HALIM
Publisher: name: Monash University
Year: 2022
Subjects: classificationCode: 320226
subject: Surgery

description: The thesis investigates the clinical aspects, mechanical physiology and pathophysiology processes specific to sleeve gastrectomy. It identified clinical problems potentially linked to physiological and pathophysiological changes, namely sleeve leaks and gastro-oesophageal reflux. Targeted and detailed clinical and physiological investigations were undertaken to define processes and outcomes. Several novel findings of altered oesophagogastric physiology of normally functioning sleeved stomachs were defined, along with pathophysiology and diagnosis of reflux.
title:  MEASUREMENT AND SIMULATION OF AEROACOUSTIC SOURCES GENERATED BY ELEMENTARY MUFFLER COMPONENTS
Creators: name: Donkin, Seth
Publisher: name: University of Kentucky Libraries
Year: 2024
Subjects: classificationCode: 2.3
subject: FOS: Mechanical engineering

description: Mufflers and silencers are commonly used to control noise from sources such as internal combustion engines and heating, ventilating, and air conditioning (HVAC) systems. In these applications, flow interacts with muffler components generating aeroacoustic noise sources. In order to measure these sources in a lab setting, specialized flow rigs are designed to isolate aeroacoustic noise sources. Flow sometimes compromises muffler performance. However, muffler performance is sometimes improved because flow can increase the attenuation of some muffler elements such as perforates. To better understand the complicated impact of flow, the University of Kentucky developed a muffler test rig to measure insertion loss and noise reduction with flow included. Additionally, the rig can be used to isolate and quantify the aeroacoustic sources inside of a muffler or at the termination. In this research, the test rig is first validated by measuring the aeroacoustic sources for a subsonic jet at the outlet of a straight pipe. Data is compared with theory to verify that the measured aeroacoustic sources match what is anticipated from well understood acoustic source power laws. The test rig is then used to measure the whistle tones generated by a perforated concentric tube resonator. The effect of hole diameter and porosity is evaluated. Finally, a subsonic jet is simulated using computational fluid dynamics and acoustic finite element analysis. The measured sound power is compared with the aeroacoustic simulation and correlation is excellent.
description: © 2024 Seth Donkin
INNOVATIVE PRECISION MEDICINE APPROACHES FOR THROMBO-INFLAMMATORY DRIVEN CARDIOVASCULAR DISEASES
Creators: name: Searle, Amy
Publisher: name: Monash University
Year: 2020
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Cardiovascular disease remains the leading cause of death worldwide, mainly driven by higher prevalence of risk factors such as diabetes and obesity. This thesis explores novel strategies to address the underlying thrombotic and inflammatory pathways that drive atherosclerosis, vulnerable plaque and aneurysm. This work encompasses a multitude of methods ranging from biomarker biology, biotechnology of antibody design and production, conjugation chemistry and various imaging modalities. It focuses on the development of a precision medicine approach via targeted theranostic tools providing visualisation of the disease and simultaneous direct and site-specific drug delivery and the ability to monitor therapeutic effects over time.
Additional file 12 of Development and validation of prognostic nomograms for early-onset colon cancer in different tumor locations: a population-based study
Creators: name: Zhu, Sirui
name: Tu, Jiawei
name: Pei, Wei
name: Zheng, Zhaoxu
name: Bi, Jianjun
name: Feng, Qiang
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer

description: Additional file 12: Table S7. Univariate and multivariable Cox analysis for CSS of the right-sided EOCCs.
On the right approach to selecting a quality improvement project in manufacturing industries
Creators: name: MITTAL, Kapil
name: TEWARI, Puran Chandra
name: KHANDUJA, Dinesh
Publisher: name: Wrocław University of Technology, Wrocław University of Economics, Polish Operational and Systems Research Society
Year: 2017
Subjects: Cost of Poor Quality (COPQ), decision tree analysis, Bayes’ theorem, fuzzy TOPSIS, project selection

description: OPERATIONS RESEARCH AND DECISIONS; ISSN 2081-8858
Additional file 5 of Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT)
Creators: name: Genta, Sofia
name: Lajkosz, Katherine
name: Yee, Noelle R.
name: Spiliopoulou, Pavlina
name: Heirali, Alya
name: Hansen, Aaron R.
name: Siu, Lillian L.
name: Saibil, Sam
name: Stayner, Lee-Anne
name: Yanekina, Maryia
name: Sauder, Maxwell B.
name: Keshavarzi, Sareh
name: Salawu, Abdulazeez
name: Vornicova, Olga
name: Butler, Marcus O.
name: Bedard, Philippe L.
name: Razak, Albiruni R. Abdul
name: Rottapel, Robert
name: Chruscinski, Andrzej
name: Coburn, Bryan
name: Spreafico, Anna
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 5: Supplementary Table 5. AutoAbs Distribution by History of Autoimmune Disease Status
An EWMA control chart for the exponential distribution using repetitive sampling
Creators: name: AZAM, Muhammad
name: ASLAM, Muhammad
name: Chi-Hyuck, JUN
Publisher: name: Wrocław University of Technology, Wrocław University of Economics, Polish Operational and Systems Research Society
Year: 2017
Subjects: control chart, EWMA statistic, exponential distribution, normal distribution, average run length

description: OPERATIONS RESEARCH AND DECISIONS; ISSN 2081-8858
Closing the Golden Door: Immigration in America
Creators: name: McDermaid, Amy B.
Publisher: name: Figshare
Year: 2018
Subjects: History

description: A growing number of Americans feel that the "golden door" of opportunity should be closed to people seeking the opulent life in this country because the swelling population of immigrants can no longer be absorbed into either the cultural or economic fabric. Immigrants are seen as threatening, primarily in terms of economic competition.
Supplemental Material – What’s in the laundromat? Mapping and characterising offshore-owned residential property in London
Creators: name: Bourne, Jonathan
name: Ingianni, Andrea
name: McKenzie, Rex
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Geography
subject: 120599 Urban and Regional Planning not elsewhere classified
subject: FOS: Social and economic geography

description: Supplemental Material for What’s in the laundromat? Mapping and characterising offshore-owned residential property in London by Jonathan Bourne, Andrea Ingianni and Rex McKenzie in Environment and Planning B: Urban Analytics and City Science
Prohibition’s Failure in Pittsburgh
Creators: name: McGee, Chris
Publisher: name: Figshare
Year: 2018
Subjects: History

description: In late 1920, one year after the Eighteenth Amendment had become law in the America, Pittsburgh was considered "the wettest spot in the United States" by Washington Prohibition leaders.1 Though not as romanticized as New York or Chicago, Pittsburgh provided more than its fair share of gangsters, open saloons, speakeasies, stills, and corrupted officials to the nation's Prohibition enforcement woes. Pittsburgh's disregard for the temperance amendment is in many ways not surprising. With its large population of recent immigrants, heavy industry, ward politics, and large size, the city faced the same cultural and political problems with enforcement as did the other major northeastern industrial centers, such as New York, Cleveland, Chicago, and Detroit
sj-docx-1-aat-10.1177_24723444221147982 – Supplemental material for Matrix Tailoring for Polyvinyl Alcohol (PVA) Fiber-Reinforced Ductile Cementitious Composites
Creators: name: Arain, Muhammad Fahad
name: Memon, Hafeezullah
name: Wang, Mingxue
name: Ahmed, Arsalan
name: Chen, Jianyong
name: Zhang, Huapeng
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-docx-1-aat-10.1177_24723444221147982 for Matrix Tailoring for Polyvinyl Alcohol (PVA) Fiber-Reinforced Ductile Cementitious Composites by Muhammad Fahad Arain, Hafeezullah Memon, Mingxue Wang, Arsalan Ahmed, Jianyong Chen and Huapeng Zhang in AATCC Journal of Research
Additional file 1 of Expression of miRNAs (146a and 155) in human peri-implant tissue affected by peri-implantitis: a case control study
Creators: name: Hamed, Munir Nasr
name: Abdulbaqi, Hayder Raad
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
sj-docx-1-taw-10.1177_20420986221143272 – Supplemental material for Development of a checklist for the assessment of pharmacovigilance guidelines in Southern Africa: a document review
Creators: name: Makhene, Nokuthula L.
name: Steyn, Hanlie
name: Vorster, Martine
name: Lubbe, Martie S.
name: Burger, Johanita R.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-taw-10.1177_20420986221143272 for Development of a checklist for the assessment of pharmacovigilance guidelines in Southern Africa: a document review by Nokuthula L. Makhene, Hanlie Steyn, Martine Vorster, Martie S. Lubbe and Johanita R. Burger in Therapeutic Advances in Drug Safety
Extension and application of cognitive work analysis to improve pedestrian safety at rail level crossings
Creators: name: Read, Gemma Jennie Megan
Publisher: name: Monash University
Year: 2019
Subjects: Uncategorized

description: Pedestrian safety at rail level crossings (RLXs) is a concern for government, the transport industry and the community. Collisions between trains and pedestrians are traditionally viewed as the result of errors or violations committed by pedestrians. However, as RLXs are complex sociotechnical systems, collisions are better understood as emergent properties of interactions amongst and between human and technical components within the system. Cognitive work analysis (CWA) is a powerful analytical framework that offers a sophisticated understanding of the functioning of RLXs as relevant to pedestrian safety, through identifying the constraints on pedestrian behaviour in this context. It does not, however, provide its users with guidance about how the findings of the analysis can be used to improve sociotechnical system functioning. Accordingly, the aim of this research was the development and evaluation of a CWA-based approach to support the design of complex sociotechnical systems, and the application of this approach to provide recommendations for RLX design to improve pedestrian safety. A secondary aim of the research was to investigate pedestrian behaviour within the RLX system using CWA. Drawing on systems theory, and more specifically, sociotechnical systems theory, the outcome of this research is a CWA design toolkit (the CWA-DT). The development and refinement of the CWA-DT is illustrated through a proof of concept application in the domain of public transport ticketing. Positive evaluation results were obtained and necessary refinements to the toolkit were implemented in the second version. A full evaluation of the toolkit was then undertaken within the complex, safety critical domain of RLXs. This evaluation found that while the CWA-DT could be considered a useful method, its application did not lead to the creation of design concepts that fully aligned with sociotechnical systems theory. The application did, however, lead to designs that were rated by human factors experts as more effective than the existing system design. These findings suggest that the sociotechnical systems theory approach may not provide an appropriate design philosophy in a public safety context. However, merging ideas and concepts from sociotechnical systems theory with existing paradigms such as safety management can lead to innovation and has the potential to improve safety performance.
Awards: Winner of the Mollie Holman Doctoral Medal for Excellence, Monash Injury Research Institute, 2015.
Additional file 7 of Development and validation of prognostic nomograms for early-onset colon cancer in different tumor locations: a population-based study
Creators: name: Zhu, Sirui
name: Tu, Jiawei
name: Pei, Wei
name: Zheng, Zhaoxu
name: Bi, Jianjun
name: Feng, Qiang
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer

description: Additional file 7: Table S2. Baseline characteristics of the left-sided EOCC patients in the training and validation cohorts.
Supplemental Material, sj-pdf-3-her-10.1177_19375867221133135 - Exploring Methodological Approaches of Experimental Studies in the Field of Neuroarchitecture: A Systematic Review
Creators: name: Rad, Parastou Naghibi
name: Behzadi, Farzaneh
name: Yazdanfar, Seyed Abbas
name: Ghamari, Hessam
name: Zabeh, Erfan
name: Lashgari, Reza
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, sj-pdf-3-her-10.1177_19375867221133135 for Exploring Methodological Approaches of Experimental Studies in the Field of Neuroarchitecture: A Systematic Review by Parastou Naghibi Rad, Farzaneh Behzadi, Seyed Abbas Yazdanfar, Hessam Ghamari, Erfan Zabeh and Reza Lashgari in HERD: Health Environments Research & Design Journal
Additional file 2 of Expression of miRNAs (146a and 155) in human peri-implant tissue affected by peri-implantitis: a case control study
Creators: name: Hamed, Munir Nasr
name: Abdulbaqi, Hayder Raad
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
Structure of Ego-alter relationships of Politicians in Twitter
Creators: name: Arnaboldi, Valerio
name: Passarella, Andrea
name: Conti, Marco
name: Dunbar, Robin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: We analyze the ego-alter Twitter networks of 300 Italian MPs and 18 European leaders, and of about 14,000 generic users. We find structural properties typical of social environments, meaning that Twitter activity is controlled by constraints that are similar to those shaping conventional social relationships. However, the evolution of ego-alter ties is very dynamic, which suggests that they are not entirely used for social interaction, but for public signaling and self-promotion. From this standpoint, the behavior of EU leaders is much more evident, while Italian MPs are in between them and generic users. We find that politicians, more than generic users, create relationships as a side effect of tweeting on discussion topics, rather than by contacting specific alters.
sj-docx-1-tam-10.1177_17588359221146137 – Supplemental material for Trifluridine/tipiracil with or without bevacizumab in metastatic colorectal cancer: results of a systematic review and meta-analysis
Creators: name: Yoshino, Takayuki
name: Taieb, Julien
name: Kuboki, Yasutoshi
name: Pfeiffer, Per
name: Kumar, Amit
name: Hochster, Howard S.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Oncology and Carcinogenesis not elsewhere classified
Aged Health Care
Pharmacology and Pharmaceutical Sciences not elsewhere classified
Respiratory Diseases

description: Supplemental material, sj-docx-1-tam-10.1177_17588359221146137 for Trifluridine/tipiracil with or without bevacizumab in metastatic colorectal cancer: results of a systematic review and meta-analysis by Takayuki Yoshino, Julien Taieb, Yasutoshi Kuboki, Per Pfeiffer, Amit Kumar and Howard S. Hochster in Therapeutic Advances in Medical Oncology
title: Ταυτόχρονη ρόφηση οργανικών ιόντων και βαρέων μετάλλων από υδατικά διαλύματα σε ενεργοποιημένα βιοεξανθρακώματα από υπολείμματα ξηρών καρπών
Creators: name: Ασημινας Γεωργιος
Publisher: name: Technical University of Crete
Year: 2024

description: Η παρούσα διπλωματική εργασία διερευνά τις δυνατότητες των αγροτικών αποβλήτων, συγκεκριμένα του βιοεξανθρακώματος από φλοιό αμυγδάλου, ως αποτελεσματικού προσροφητικού υλικού για την απομάκρυνση βαρέων μετάλλων και οργανικών ιόντων από υδατικά διαλύματα. Δεδομένης της περιβαλλοντικής απειλής που προκαλεί η ακατάλληλη διαχείριση των αγροτικών αποβλήτων και η ρύπανση του νερού από βαρέα μέταλλα και ιόντα όπως το αρσενικό (As), το στρόντιο (Sr), το αμμώνιο (NH4+) και τα φωσφορικά (PO43-), είναι κρίσιμη η ανάπτυξη αποδοτικών και οικονομικά βιώσιμων μεθόδων απορρύπανσης.
Η πυρόλυση των φλοιών αμυγδάλου στους 700°C, ακολουθούμενη από ενεργοποίηση με ατμό, αλλά και χημική τροποποίηση με δολομίτη, παρήγαγε βιοεξανθράκωμα με βελτιωμένες προσροφητικές ιδιότητες. Οι πειραματικές διαδικασίες περιελάμβαναν την έκθεση του βιοεξανθρακώματος σε υδατικά διαλύματα που περιείχαν διάφορες συγκεντρώσεις (από 10 mg/L έως 300 mg/L) από αυτούς τους ρύπους, τόσο μεμονωμένα όσο και ταυτόχρονα, και την αξιολόγηση της αποδοτικότητας της προσρόφησης σε διαφορετικές δοσολογίες (2g/L και 4g/L) σε ενεργοποιημένο με ατμό, αλλά και σε τροποποιημένο με δολομίτη βιοεξανθράκωμα.
Η ισορροπία προσρόφησης αναλύθηκε χρησιμοποιώντας τα μοντέλα Langmuir και Freundlich και προέκυψε πως το μοντέλο του Freundlich ήταν το επικρατέστερο στην προσομοίωση των πειραματικών δεδομένων, σε όλες τις περιπτώσεις. Συγκεκριμένα, οι βέλτιστες ικανότητες προσρόφησης επιτεύχθηκαν στο μη τροποποιημένο βιοεξανθράκωμα, με δοσολογία 2g/L. Η μέγιστη ικανότητα προσρόφησης για το Sr ήταν 64.2 mg/g, για το As 63 mg/g,  για το PO43- 121 mg/g και για το NH4+ 45.4 mg/g. Στο τροποποιημένο με δολομίτη δείγμα η ικανότητα προσρόφησης των βαρέων μετάλλων Sr και Αs, καθώς και του NH4+, βελτιώθηκε σε μικρό ποσοστό. Εξαίρεση αποτέλεσε η προσρόφηση του  PO43-,  που για δοσολογία προσροφητή 4g/L αυξήθηκε από 59.2 mg/g σε 74 mg/g και για δοσολογία προσροφητή 2g/L προσομοιώθηκε καλύτερα από το μοντέλο του Langmuir με μέγιστη τιμή 74.3 mg/g. Η φασματοσκοπία υπέρυθρου μετασχηματισμού Fourier (FTIR) χρησιμοποιήθηκε για τον προσδιορισμό των μηχανισμών δέσμευσης.
Additional file 13 of Development and validation of prognostic nomograms for early-onset colon cancer in different tumor locations: a population-based study
Creators: name: Zhu, Sirui
name: Tu, Jiawei
name: Pei, Wei
name: Zheng, Zhaoxu
name: Bi, Jianjun
name: Feng, Qiang
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer

description: Additional file 13: Table S8. Univariate and multivariable Cox analysis for CSS of the left-sided EOCCs.
Additional file 3 of Expression of miRNAs (146a and 155) in human peri-implant tissue affected by peri-implantitis: a case control study
Creators: name: Hamed, Munir Nasr
name: Abdulbaqi, Hayder Raad
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 3
Additional file 1 of TonEBP inhibits ciliogenesis by controlling aurora kinase A and regulating centriolar satellite integrity
Creators: name: Chinbold, Batchingis
name: Kwon, Hyug Moo
name: Park, Raekil
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer

description: Supplementary Material 1
Additional file 1 of RNA-binding protein GIGYF2 orchestrates hepatic insulin resistance through STAU1/PTEN-mediated disruption of the PI3K/AKT signaling cascade
Creators: name: Lv, Ziwei
name: Ren, Yuanyuan
name: Li, Yang
name: Niu, Fanglin
name: Li, Zhuozhuo
name: Li, Man
name: Li, Xiaofang
name: Li, Qinhua
name: Huang, Deqing
name: Yu, Yi
name: Xiong, Yuyan
name: Qian, Lu
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Virology

description: Supplementary Material 1
Additional file 4 of Expression of miRNAs (146a and 155) in human peri-implant tissue affected by peri-implantitis: a case control study
Creators: name: Hamed, Munir Nasr
name: Abdulbaqi, Hayder Raad
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 4
sj-docx-8-car-10.1177_19476035221141417 – Supplemental material for Improved Understanding of the Inflammatory Response in Synovial Fluid and Serum after Traumatic Knee Injury, of Excluding Fractures the Knee: A Systematic Review
Creators: name: Nieboer, Michael F.
name: Reijman, Max
name: Wesdorp, Marinus A.
name: Bastiaansen-Jenniskens, Yvonne M.
name: Meuffels, Duncan E.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, sj-docx-8-car-10.1177_19476035221141417 for Improved Understanding of the Inflammatory Response in Synovial Fluid and Serum after Traumatic Knee Injury, of Excluding Fractures the Knee: A Systematic Review by Michael F. Nieboer, Max Reijman, Marinus A. Wesdorp, Yvonne M. Bastiaansen-Jenniskens and Duncan E. Meuffels in CARTILAGE
Das antiinflammatorische Potential von Ebselen auf das geschlossene Weichteiltrauma
Creators: name: Röther, Julia
Publisher: name: Universität Rostock
Year: 2012
Subjects: subject: 610 Medical sciences Medicine

description: Anhand eines bereits etablierten Traumainduktionsmodells konnte der günstige Einfluss der selenoorganischen Substanz Ebselen auf das geschlossene Weichteiltrauma und dem resultierenden, sekundären Gewebeschaden nachgewiesen werden. Im Mittelpunkt der Untersuchungstechnik stand die intravitalmikroskopischen Analyse. Zusammenfassend zeigen die Ergebnisse dieser Arbeit, dass die Applikation von Ebselen eine effektive Behandlungsstrategie der durch Trauma induzierten Mikrozirkulationsstörungen darstellt, wobei eine nahezu vollständige Wiederherstellung der Zirkulation erreicht werden konnte.
Quantum Chemistry on Quantum Computers
Creators: name: Possel, Clemens
name: Omlor, Andreas
name: Hahn, Walter
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2023

description: Quantum Computing has great potential to boost modern computer science. One of the most promising applications is in the area of quantum chemistry. The aim hereby is to calculate molecular energy eigenstates utilizing a quantum computer, which is a well-controlled quantum system. In recent years, significant progress has been made in quantum hardware and software; however, further steps are still needed to harness quantum effects in practice to eventually achieve quantum advantage.
Kundendichte im Handel
Customer density in retail stores
Creators: name: Uhrich, Sebastian
Publisher: name: Universität Rostock
Year: 2012
Subjects: subject: 330 Economics

description: Die vorliegende Arbeit untersucht, wie die Anzahl anderer, fremder Kunden in einem Handelsgeschäft das Kundenverhalten beeinflusst. Speziell geht es um die Frage, wie negative Effekte durch die Anwesenheit zu weniger anderer Kunden auf die Emotionen und das Verhalten eines Handelskunden erklärt werden können. Die Untersuchung identifiziert zunächst Erklärungsmechanismen anhand qualitativer Studien und prüft ihre Relevanz daraufhin mittels mehrerer experimenteller Studien. Die Ergebnisse tragen dazu bei, das Kundenverhalten besser zu verstehen, und liefern Ansatzpunkte für das Handelsmanagement.
Verlaufsuntersuchungen bei Autoimmunhepatitis
Creators: name: Erdmann, Christian
Publisher: name: Universität Rostock
Year: 2011
Subjects: subject: 610 Medical sciences Medicine

description: Ziel und Inhalt der Dissertation war die Erkennung und Zusammenfassung von Merkmalen, die zur AIH-Diagnosestellung bei Patienten in Mecklenburg-Vorpommern führen. Dabei wurden die Untersuchungsergebnisse teils über mehrere Jahre einer klinischen Beobachtungszeit detailliert ausgewertet. Zusätzlich wurden unterschiedliche Therapiestrategien überprüft und ausgewertet sowie abschließend die Effektivität einer Behandlung hinsichtlich Remission, Teilremission sowie Therapieversagern eingeordnet.
Supplemental Material - The Double-Edged Sword of Foreign Direct Investment on Domestic Terrorism
Creators: name: Biglaiser, Glen
name: Hunter, Lance Y
name: McGauvran, Ronald J
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material for The Double-Edged Sword of Foreign Direct Investment on Domestic Terrorism by Glen Biglaiser, Lance Y. Hunter, and Ronald J. McGauvran in Journal of Conflict Resolution
Additional file 1 of Correction to: London protocol under water-perfused HRM in a healthy population, towards novel 3D manometric parameters in an evaluation of anorectal functional disorders
Creators: name: Anefalos, Alexandre
name: Real Martinez, Carlos Augusto
name: Coy, Claudio Saddy Rodrigues
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 1
PROMOTING START-UP ENTERPRISES THROUGH SUPPORT ACTIVITIES FOR SMALL AND MEDIUM ENTERPRISES IN VIETNAM - CURRENT STATUS AND PERFORMANCE DIRECTIONS
Creators: name: Seybold Report Journal
Publisher: name: Seybold Report Journal
Year: 2024

description: Abstract

The COVID-19 pandemic has seriously affected life as well as production and business. According to data from the Business Registration Administration, the total number of newly established enterprises in 2021 is 116,839, down 13.4% compared to 2020, the number of businesses returning to operation is 43,116. down 2.2% compared to 2020. To promote economic recovery, the Government has issued and implemented many fiscal-monetary policies. In addition, many legal policies to support small and medium-sized enterprises were born. structuring, the article will focus on pointing out the current state of legal regulations related to the support mechanism for small and medium-sized enterprises, naturally a proposal to improve the support mechanism for small and medium-sized enterprises. small and medium in the current period .

Keywords: Support, Enterprise support law, Small and medium enterprises
sj-docx-1-jht-10.1177_10963480231152571 – Supplemental material for A Systematic Analysis of Diaspora Tourism: Geographical Perspectives and Superdiversity
Creators: name: Liu, Adrienne Tingyao
name: Williams, Allan M.
name: Liu, Anyu
name: Kim, Yoo Ri
name: Lin, Pearl M.C.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental material, sj-docx-1-jht-10.1177_10963480231152571 for A Systematic Analysis of Diaspora Tourism: Geographical Perspectives and Superdiversity by Adrienne Tingyao Liu, Allan M. Williams, Anyu Liu, Yoo Ri Kim and Pearl M.C. Lin in Journal of Hospitality & Tourism Research
sj-docx-1-smo-10.1177_20503121221149535 – Supplemental material for Alcohol use and associated factors among pregnant women during the mid-pandemic of COVID-19 at Debre Tabor Comprehensive Specialized Hospital, South Gondar Zone, Ethiopia
Creators: name: Shitie, Anguach
name: Birhanu, Alemu
name: Worku, Amsalu
name: Melese, Ergoye
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-docx-1-smo-10.1177_20503121221149535 for Alcohol use and associated factors among pregnant women during the mid-pandemic of COVID-19 at Debre Tabor Comprehensive Specialized Hospital, South Gondar Zone, Ethiopia by Anguach Shitie, Alemu Birhanu, Amsalu Worku and Ergoye Melese in SAGE Open Medicine
Identifizierung eines hochgradig mikrosatelliteninstabilen (MSI-H) spezifischen zytotoxischen T-Zell Epitopes, welches durch eine (-1)-Leserastermutation im Gen U79260 (Fat Mass and Obesity associated) generiert wird
Creators: name: Wienck, Anne
Publisher: name: Universität Rostock
Year: 2012
Subjects: subject: 610 Medical sciences Medicine

description: Bei steigender Letalität insbesondere in fortgeschrittenen Tumorstadien spielt die Behandlung des CRCs weiterhin eine große Rolle. In dieser Arbeit wurde ein Neopeptid FSP11 (TLSPGWSAV) mit der Fähigkeit zur Induktion von HLA-A0201-restringierten CTLs charakterisiert. Diese waren in der Lage, Tumorzellen mit der zugrundeliegenden Mutation zu lysieren, somit konnte ein Neopeptid spezifisch für MSI-H CRC charakterisiert werden, und es steht dem Immunsystem ein Angriffspunkt zur Tumorabwehr zur Verfügung. Dies eröffnet die Möglichkeit der Entwicklung von spezifischen Immuntherapien bei MSI-H CRC.
sj-docx-1-wso-10.1177_17474930231152132 – Supplemental material for Association of post-stroke fatigue with physical activity and physical fitness: A systematic review and meta-analysis
Creators: name: Larsson, Petra
name: Bidonde, Julia
name: Olsen, Unni
name: Gay, Caryl L
name: Lerdal, Anners
name: Ursin, Marie
name: Mead, Gillian Elizabeth
name: Edvardsen, Elisabeth
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-wso-10.1177_17474930231152132 for Association of post-stroke fatigue with physical activity and physical fitness: A systematic review and meta-analysis by Petra Larsson, Julia Bidonde, Unni Olsen, Caryl L Gay, Anners Lerdal, Marie Ursin, Gillian Elizabeth Mead and Elisabeth Edvardsen in International Journal of Stroke
Sekundäre Pflanzeninhaltsstoffe für die Krebsprävention und - therapie
Creators: name: Oppermann, Christina
Publisher: name: Universität Rostock
Year: 2012
Subjects: subject: 540 Chemistry & allied sciences

description: Krebs ist eine der am häufigsten vorkommenden Krankheiten in der westlichen Welt. Auffällig ist die Wirkung der Phytoöstrogene auf die hormonabhängigen Erkrankungen wie Brust- und Prostatakrebs. Im Rahmen dieser Arbeit wurden ethanolische Mikrowellenextrakte aus einheimischen Pflanzen gewonnen. Anschließend wurden deren zellbiologische Eigenschaften an verschiedenen Brustkrebszelllinien getestet. Die massenspektrometrische Analyse der Inhaltsstoffe gab Aufschluss über die Substanzen bzw. Substanzklassen, die entscheidend für die Proliferationshemmung der Brustkrebszelllinien sind.
sj-pdf-1-pmj-10.1177_02692163231152525 – Supplemental material for Communication in the context of glioblastoma treatment: A qualitative study of what matters most to patients, caregivers and health care professionals
Creators: name: Boele, Florien W
name: Butler, Sean
name: Nicklin, Emma
name: Bulbeck, Helen
name: Pointon, Lucy
name: Short, Susan C
name: Murray, Louise
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-pmj-10.1177_02692163231152525 for Communication in the context of glioblastoma treatment: A qualitative study of what matters most to patients, caregivers and health care professionals by Florien W Boele, Sean Butler, Emma Nicklin, Helen Bulbeck, Lucy Pointon, Susan C Short and Louise Murray in Palliative Medicine
Der Wandel in der Diagnostik und Therapie der Adnexitis im Zeitraum 1998-2007
Creators: name: Krohn, Katharina
Publisher: name: Universität Rostock
Year: 2012
Subjects: subject: 610 Medical sciences Medicine

description: In dieser Arbeit wurden Daten der Universitätsfrauenklinik Rostock von 1998 bis 2007 ausgewertet. Es konnte gezeigt werden, dass jugendliches Alter und Rauchen Risikofaktoren für die akute Adnexitis und die Verwendung eines IUDs Risikofaktor für komplizierte Adnexitis war. Portioschiebeschmerz, sonografischer Adnextumor, erhöhte Leukozyten, CRP und BSG zeigten sich als entscheidende Diagnostika. Der mikrobiologische Nachweis nahm zu. Bei Vorliegen eines Abzesses war die operative Sanierung indiziert. Es vollzog sich ein Wandel weg von der operativen Therapie hin zur antibiotischen Therapie.
Additional file 8 of Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT)
Creators: name: Genta, Sofia
name: Lajkosz, Katherine
name: Yee, Noelle R.
name: Spiliopoulou, Pavlina
name: Heirali, Alya
name: Hansen, Aaron R.
name: Siu, Lillian L.
name: Saibil, Sam
name: Stayner, Lee-Anne
name: Yanekina, Maryia
name: Sauder, Maxwell B.
name: Keshavarzi, Sareh
name: Salawu, Abdulazeez
name: Vornicova, Olga
name: Butler, Marcus O.
name: Bedard, Philippe L.
name: Razak, Albiruni R. Abdul
name: Rottapel, Robert
name: Chruscinski, Andrzej
name: Coburn, Bryan
name: Spreafico, Anna
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 8: Supplementary Fig. 1. Frequencies of different irAEs G≥2.
Design and Synthesis of Pyrimidine C-Nucleosides, 5-Polyfluoroalkyl-5-deazaalloxazines and Spiro[pyrimido[4,5-b]quinoline-3',5-indoline-2'-one]-3,10-dihydro-2,4-diones
Creators: name: Dudkin, Sergii
Publisher: name: Universität Rostock
Year: 2013
Subjects: subject: 540 Chemistry & allied sciences

description: A wide range of novel 2-(β-D-ribofuranosyl)pyrimidines was synthesized by 3+3 cyclocondensation. Reaction of 6-arylamino-1,3-dialkyluracils with perfluorinated carboxylic acid anhydrides or chloroanhydrides and subsequent cyclization gave the corresponding 1,3-dialkyl-5-(polyfluoroalkyl)-5-deazaalloxazines. An unexpected recyclization in the series of spiro[indole-3,5'-pyrimido[4,5-b]quinoline]-2,2',4'-trione derivatives, carried out via a reaction between (thio)barbituric acids, isatins and electron-rich aromatic amines, was observed.
Privacy Management in Smart Environments
Creators: name: Bünnig, Christian
Publisher: name: Universität Rostock
Year: 2012
Subjects: subject: 004 Data processing Computer sciences

description: This thesis addresses the issue of managing privacy in smart environments, while emphasizing problems and solutions in context of interpersonal privacy. It elaborates different concepts of privacy and how smart environments interfere with these concepts. In this context this work develops solutions to understand patterns of interpersonal privacy management, to orchestrate different disclosure control methods to a composite disclosure control system, and to automate disclosure decisions using machine learning techniques.
Morphometrische und histologische Untersuchungen von 10 Unterkiefer bei Foeten im Alter von 16 bis 26 Schwangerschaftswochen
Creators: name: Lenz, Jan-Hendrik
Publisher: name: Universität Rostock
Year: 2008
Subjects: subject: 610 Medical sciences Medicine

description: Es ist eine hohe Korrelation der Unterkieferlänge zur Scheitel-Steiss-Länge als auch der Unterkieferbreite zum SS-Alter messbar, ebenfalls der Parameter Unterkieferlänge und -breite. Asymmetrien sind vorhanden, seiten- und altersunabhängig. Das lineare Längenwachstum ist unabhängig von Remodellation und desmalen/periostalen Wachstumsvorgängen. Die Wachstumsentwicklung von Corpus und Ramus mandibulae verläuft linear parallel. Am Gelenkfortsatz ist periostales Wachstum der primäre Faktor für die Größenzunahme, am horizontalen Ast desmales Wachstum. Typische Knorpelkerne werden nicht beobachtet.
sj-pdf-1-ajs-10.1177_03635465221146294 – Supplemental material for A Multidimensional Assessment of a Novel Adaptive Versus Traditional Passive Ankle Sprain Protection Systems
Creators: name: Willwacher, Steffen
name: Bruder, Anna
name: Robbin, Johanna
name: Kruppa, Jakob
name: Mai, Patrick
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_03635465221146294 for A Multidimensional Assessment of a Novel Adaptive Versus Traditional Passive Ankle Sprain Protection Systems by Steffen Willwacher, Anna Bruder, Johanna Robbin, Jakob Kruppa and Patrick Mai in The American Journal of Sports Medicine
Polyurethane seating structure for aviation applications - environmental improvements
Creators: name: Höhne, Carl-Christoph
name: Hanich-Spahn, Ronny
name: Brantsch, Peter
name: Nioac De Salles, Ana Claudia
name: Ilinzeer, Sergej
name: Emmerich, Rudolf
name: Reichert, Thomas
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2023
Subjects: Clean Sky
Clean Aviation
Eco TA
Aviation
ecoDESIGN
Hybrid Seating Structure
Airframe
Life Cycle Assessment
LCA
Sustainability
Productivity
CRRP
Polyurethanes

description: The main challenge of a sustainable and recyclable product is currently the step between product end-of-life and the new product generation - the recycling step. Fraunhofer ICT is developing a sustainable seating structure for aviation. The majority of parts used in the seating structure, from foam cushions to the composite seat structure, are based on polyurethane (mono-material approach). A holistic product development is used, taking into account all phases of the product‘s life cycle - from raw material extraction to end-of-life. In addition to economic advantages and product properties, the ecological impact is integrated into the product development as a third optimization parameter - so a demonstrably sustainable product is developed.
Pembelajaran Aktif dan Menyenangkan: Upaya Meningkatkan Motivasi Belajar Siswa Sekolah Dasar
Creators: name: Helena Badu
Publisher: name: Zenodo
Year: 2024

description: Tujuan yang ingin dicapai dalam kegiatan pengabdian ini adalah meningkatnya motivasi belajar siswa, serta bertambahnya pembendaharaan kata dalam bahasa inggris. Siswa diajarkan dengan menggunakan berbagai strategi, metode yang aktif dan menyenangkan seperti penerapan games, songs, serta penerapan media yang menarik.  Siswa dari berbagai tingkatan kelas yang berjumlah 7 orang merupakan sasaran dalam kegiatan ini yang berlokasi di Rumah Bermain dan Belajar, Griya Nabilla Permai, Kelurahan Tapa, Kecamatan Sipatana, Kota Gorontalo. Kegiatan ini dilaksanakan dalam empat kali pertemuan, dengan metode dan materi yang berbeda pada setiap pertemuan.  Hasil dari kegiatan pengabdian ini menunjukkan bahwa para siswa merasa senang dan termotivasi dalam belajar bahasa inggris.
Zur Regulation des Neurotrophins Brain-derived neurotrophic factor (BDNF) bei Patienten mit stabiler chronisch obstruktiver Lungenerkrankung (COPD)
Creators: name: Würtemberger, Urs
Publisher: name: Universität Rostock
Year: 2017
Subjects: subject: 610 Medical sciences Medicine

description: Die chronisch obstruktive Lungenkrankheit (COPD) ist eine Volkserkrankung mit zunehmender Bedeutung. Der Thrombozytenmediator Brain-Derived Neurotrophic Factor (BDNF) kann neuronale und muskuläre Funktionen regulieren. Der Thrombozytenmediator Transforming Growth Factor ß1 (TGF-ß1)ist bei der extrazellulären Kollagenablagerung beteiligt. In der vorliegenden Arbeit zeigte sich eine systemische Hochregulierung von BDNF sowie erhöhte Serumkonzentrationen von TGF-ß1. Somit bestehen Hinweise auf eine neuromuskuläre Dysfunktion bei COPD sowie auf eine pathogenetische Rolle dieser Mediatoren.
In situ Umsetzung von verbrückten dimeren Rhodium(I)-Olefinkomplexen mit Bisphosphanliganden
Creators: name: Meißner, Antje
Publisher: name: Universität Rostock
Year: 2017
Subjects: subject: 540 Chemistry & allied sciences

description: Neutrale dimere µ2-X verbrückte Rhodiumkomplexe des Typs [Rh(Bisphosphan)(µ2-X)]2 werden in der homogenen Katalyse als Katalysatorvorstufen eingesetzt und oft in situ durch Ligandenaustausch an Vorstufen wie [Rh(Diolefin)(µ2-X)]2 generiert. Abhängig vom Liganden, dem Lösungsmittel, der Temperatur sowie der Vorstufe bilden sich auch andere Spezies als der erwartete Zweikernkomplex, womit diese Methode zur Synthese nicht allgemeingültig ist. Eine Anwendung dieser in situ generierten Rhodiumkomplexe ist die Addition von Carbonsäuren an terminale Alkine, welche ausführlich untersucht wurde.
Prospective clinical study comparing intraligamentary anesthesia and inferior alveolar nerve block for extraction of mandibular posterior teeth
Klinisch-vergleichende Untersuchungen der intraligamentären Anästhesie mit der Leitungsanästhesie des Nervus alveolaris inferior bei den Extraktionen von Unterkieferseitenzähnen
Creators: name: Adubae, Ahmed
Publisher: name: Universität Rostock
Year: 2017
Subjects: subject: 610 Medical sciences Medicine

description: This study was conducted to test the efficacy of intraligamentary anesthesia using a pistol type syringe with pressure limiting mechanism for extraction of mandibular posterior teeth in comparison to inferior alveolar nerve block. Primary objective was to evaluate the differences in pain during treatment as well as in anesthetic quality. Intraligamentary anesthesia is comparable to the inferior alveolar nerve block in respect to the success rate and the profoundness of anesthesia. In addition, intraligamentary anesthesia offers many advantages for both the practitioner and the patient.
ML-Space
Creators: name: Bittig, Arne T.
Publisher: name: Universität Rostock
Year: 2017
Subjects: subject: 000 Generalities, Science

description: Computer simulations of biological cells as well-stirred systems are well established  but neglect the spatial distribution of key actors. In this thesis, a simulation algorithm "ML-Space" for spatial models with dynamic hierarchies is presented. It combines stochastic spatial algorithms in discretized space with individual particles moving in continuous space that have spatial extensions and can contain other particles. For formal descriptions of the systems to be simulated spatially, ML-Space provides a rule-based specification language.
Wnt3a induces neuronal differentiation and crosstalk between Wnt/Ca2+-pathway and Wnt/β-catenin pathway
Creators: name: Talabattula, Venkata Ajay Narendra
Publisher: name: Universität Rostock
Year: 2017
Subjects: subject: 610 Medical sciences Medicine

description: HumanNPCs (hNPCs) are the suitable cell source in translation medicine for neurodegenerative disease. In the present study, effects of Wnt3a on the differentiation of hNPC were studied. The results showed that Wnt3a induces canonical and non canonical Wnt pathways. Furthermore, Wnt3a increases Ca2+ target genes CaMKII and Pyk2 in the differentiating VM cells. The results demonstrated that Pyk2 decreases GSK3β activity and stabilizes β-catenin, suggesting there is an intercross between Wnt/β-catenin and Wnt/Ca2+-pathway via Pyk2.