cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Novel small molecules and new strategies for probing inhibition of telomerase
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Our proposed study, which represents a new research direction for us, is intended to provide the first meaningful insight required for developing a telomerase inhibitor scaffold which acts outside the RNA template region. It provides a new modality for systemic anti-cancer therapy. The limiting factor for the development of specific and potent inhibitors has been the complexity that surrounds human telomerase (h-telomerase). The minimally active dimer is composed of two h-TERT catalytic proteins, two h-TR RNA components, and two dyskerin proteins; additionally there are currently twenty known associated proteins which modulate telomerase activity. The presence of two active sites and multiple associations makes the interpretation of meaningful mechanistic data for small molecules very dubious. Some progress has been made by targeting the RNA template involved in the 3’-extension reaction. Complementary synthetic oligonucleotides, such as GRN 163L, hybridize to the h-TR template region competitively preventing substrate binding. Another strategy targets the ssDNA substrate by stabilizing its G4-quadruplex secondary structure thereby sequestering it from the enzyme. Although these inhibitors are rationally designed, they face bioavailability, manufacturing, and licensing complications. Screening efforts have led to fewer than eight structural classes of small molecule telomerase inhibitors; none have been connected to a concrete mechanism of action, and thus all commercial efforts have been halted. We believe researchers armed with small molecule probes can circumvent many of these problems and elucidate the specifics of how these reported inhibitors act against telomerase function in a simpler monomeric tetrahymena telomerase, and the results will transpose to the h-telomerase. We have challenged the non-human system with all of the known small molecule h-telomerase inhibitors, and identified four compounds showing similar potencies towards both enzymes and established their mode of inhibition in the simpler monomer tetrahymena. We propose to synthesize crosslinking analogs of rubromycin, which is the most potent and least promiscuous of inhibitors examined, and then covalently link these by azide photolysis to the tetrahymena enzyme. After establishing crosslinking by LC MS/MS, TAGGED crosslinked conjugates would be further analyzed so as to identify the specific amino-acid of coupling and thus the specific site where the inhibitor binds. This unconventional identification of the exact mechan
The hard clam research initiative: Factors controlling Mercenaria mercenaria populations in the South Shore Bays of Long Island, NY
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2009

description: This report compiles summarize key results of five research projects funded through New York Sea Grant’s Hard Clam Research Initiative (HCRI) between 1999 and 2008. It presents research to improve science-based understanding of the factors controlling hard clam, Mercenaria mercenaria, populations in Long Island, New York’s south shore estuaries, and thereby contribute towards better management and potential enhancement of a once highly productive regional resource. Topics include: impact of fishing; reproduction; trophic interactions between hard clams and the natural phytoplankton; copepod-hard clam grazing interactions; and potential impacts of climate change. Particular emphasis is given in this synthesis to findings that have direct implications for management of these populations.
Regulation of surface titer of the multidrug efflux transporters ABCB1, ABCC1 and ABCG2 during epithelial-mesenchymal transition
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: ATP Binding Cassette (ABC) transporter-mediated multidrug resistance (MDR) is closely linked to poor clinical outcome of breast, lung, myeloma, prostate and pancreatic cancers. ABC MDR is usually acquired after metastasis, a process that requires drastic changes in the structural and functional organization of cancer cells. One of the hallmarks of metastatic change is the epithelial-mesenchymal transition (EMT), which leads to conspicuous changes in cell polarity and organization of cell surfaces. Less understood is how EMT-related cortical changes mediate increased surface expression of the ABC MDR transporters. The overall goal of this proposal is to understand the cellular interplay between EMT-mediated changes in cortical organization and regulation of surface expression of MDR transporters. We will use a well-characterized developmental EMT in sea urchin embryos, involving transition of micromeres to primary mesenchyme cells, as a system to explore how EMT-related changes in endosomal cycling regulate the surface titer of MDR transporters. We have characterized the sea urchin orthologs of the major multidrug efflux pumps ABCB1, ABCC1 and ABCG2, and found that these proteins have similar substrate specificity to their human counterparts. We will use biochemical, live-cell and super-resolution (3D SIM) immunolocalization approaches to identify changes in the association of these ABC MDR transporters with rab GTPases and test whether these pathways alter transporter surface titer; either through increases in membrane insertion and/or decreases in membrane retrieval of the MDR pumps. Our previous research focused on understanding the role of ABC transporters in developmental signaling and embryonic protection (e.g. Campanale and Hamdoun, Development 2012). This support is requested from the CRCC as the launching point for a new avenue of cancer-focused work on the relationship between ABC MDR transporters and EMT. Since drugs that target efflux activity of MDR ABC transporters have thus-far been ineffective in the clinic, this work could identify new targets that perturb surface expression of the transporters in metastatic cancer cells.
Boydaia indica Fain 1969
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Boydaia
Boydaia indica

description: Boydaia indica Fain, 1969
Boydaia indica Fain, 1969: 373, fig. 5. Holotype in RBINS, examined. Boydaia (Boydaia) indica, Fain 1971: 101, 110, fig. 16.
Type host: Acridotheres tristis (Linnaeus) (Passeriformes: Sturnidae) from India.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Setae vi situated posterior to level of setae si. Sensillae SEa- or SEb-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–1–1, trochanters 1–1–0–0, femora 7–4–3–2, genua 4–4–3–3, tibiae 5–3–3–3. All setae on genu and tibia of leg I similar in shape. In larvae, antaxial and paraxial claws of leg I long, subequal, and sharp-ended.
Hosts and distribution. Passeriformes (Sturnidae): LamprOtOrnis chalybaeus Hemprich and Ehrenberg from Sub-Saharan Africa (based on host distribution (Clements et al. 2016); org. died in captivity in Antverp, Belgium (Fain 1971)), L. chlOrOpterus chlOrOpterus Swainson from Democratic Republic of Congo (Fain 1969, 1971), L. superbus Rueppell from East Africa (based on host distribution (Clements et al. 2016); org. died in captivity in Antverp, Belgium (Fain 1971).
Non-African hosts and distribution. Sturnidae: Gracupica cOntra (Linnaeus) (= SturnOpastOr capensis), Sturnia malabarica (Gmelin) and S. pagOdarum (Gmelin) all from India and died in captivity in Belgium (Fain 1969).
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 424, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Traditional Medicine: An adaptation strategy towards ameliorating the impacts of climate change on human health in Pacific Island Countries – A case study of Fiji
Creators: name: Ezedinma, Uchenna
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2020
Subjects: Fiji
climate change
traditional medicine
antimicrobial
diarrheal disease

description: Pacific Island Countries (PICs) are most vulnerable to climate-mediated diseases such as diarrhoea, dengue, and acquired respiratory infection, due to their geographical location, low socioeconomic level and inadequate health infrastructure. In Fiji, climate-mediated diarrheal disease is an increasingly current and future public health risk due to its high prevalence and sensitivity to sea-level rise and increasing temperature. While studies allude to the use of local knowledge of Traditional Medicine (TM) as an effective adaptation strategy towards ameliorating the impacts of climate-mediated diarrheal disease, there is little scientific evidence on the effectiveness of such therapies against common diarrheal causing pathogens. This study assessed the antibacterial effectiveness of frequently used traditional medicinal plants (TMPs) against prevalent diarrheal causing bacterial pathogens in Fiji.
description: The research approach used in this study centres on the Multiple-Evidence Based concept (MEB). Data retrieved from relevant scientific literature and discussions with an expert on Fiji’s traditional medicine identified frequently used TMPs in the treatment of diarrheal disease in Fiji. Subsequently, extracts from the selected TMPs were analysed for their chemical characteristics using High-Performance Liquid Chromatography (HPLC). Assessing the antibacterial action of these extracts against common bacteria causing diarrhea pathogens was conducted using the broth microdilution and antibiofilm formation assays.
description: Results identified Cordia subcordata, Psidium guajava, Solanum melongena and Vigna marina as four of the most frequently used TMPs in the treatment of diarrheal disease in Fiji. Extracts from each TMPs showed antibacterial and/or antibiofilm activity (MIC = 0.1-0.4mg/ml) against Escherichia coli 30-KH, Salmonella typhimurium ATCC 53648, Staphylococcus aureus 29247 TSA, E. coli S6.CH10, E. coli S3.H20, E. coli S7. P18 and E. coli Xen18. While the antibacterial action of the extracts was mostly limited to pathogens from human sources and absent against Multidrug resistant-E. coli NHP2K, this was consistent with the challenges of assessing TMPs using the scientific method. Furthermore, with increased future inundation related to climate change, the government needs to develop policy and lead practice to help prevent bacterial water contamination, especially originating from animal sources.
description: The overall finding from this study supports the view that if scientifically assessed, TMPs can be effective in the design and development of an effective adaptation strategy in addressing the public health threat posed by climate-mediated diarrheal disease in PICs.
Boydaia nectarinia , Fain 1958
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Boydaia
Boydaia nectarinia

description: Boydaia nectarinia Fain, 1958
Boydaia (Boydaia) nectarinia Fain, 1958b: 180, figs. 1–3, 1963d: 59, 67, fig. 25, 1971: 100, 109, fig. 14. Holotype in RMCA, examined.
Type host: Cyanomitra verticalis viridisplendens (Reichenow) (Passeriformes: Nectariniidae) from Rwanda.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Setae vi situated posterior to level of setae si. Sensillae SEc-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–1–0, trochanters 1–1–0–0, femora 5–4–3–2, genua 4–4–3–3, tibiae 5–3–3–3. All setae on tibia and genu of leg I similar in shape. In larvae, antaxial and paraxial claw pair of leg I subequal and sharp-ended.
Host and distribustion. Passeriformes (Nectariniidae): CyanOmitra verticalis viridisplendens (Reichenow) from Rwanda [Southern Prov., Akanyaru] (Fain 1958b).
Remark. Currently, ChalcOmitra senegalensis lamperti (Reichenow) and Cinnyris cupreus cupreus (Shaw) both from Rwanda (Fain 1958) are hosts for BOydaia cinnyris Fain, 1969.
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 424, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Neotyphloceras crassispina subsp. hemisus Jordan 1936
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Hystrichopsyllidae
Neotyphloceras
Neotyphloceras crassispina
Neotyphloceras crassispina hemisus jordan, 1936

description: Neotyphloceras crassispina hemisus Jordan, 1936
NHM. Argentina—Catamarca: Otro Cerro, Capayán. Mammalia—Rodentia—Cricetidae— Andinomys edax. Bolivia; Peru; Chile; Argentina—Catamarca: Antofagasta de la Sierra, Laguna Blanca, Belén, Paclín, Paycuqui. Jujuy: Chilcayoc, Cuesta del Hurón, Curques, La Quiaca, Salar Cauchari, Santa Catalina, Sierra de Zenta, Susques, Tumbaya, Yavi. Mendoza: Santa Rosa. Neuquén: Lago Curruhue Grande, Pampa de Hui Hui, Piedra Pintada. Río Negro: Pilcañeu. Salta: Chicoana, Los Andes, Rosario de la Frontera, Vega Cortadera, Yaco. Mammalia— Rodentia—Cricetidae— Abrothrix andinus, Akodon albiventer, Akodon simulator, Akodon spegazzinii, Eligmodontia bolsonensis, Eligmodontia hirtipes, Eligmodontia puerulus, Graomys griseoflavus, Necromys lactens, Oligoryzomys destructor, Phyllotis cf. osilae, Phyllotis xanthopygus, Reithrodon auritus. Lareschi et al. (2010), López Berrizbeitia et al. (2013; 2015).
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 243, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Boydaia psalidoprocnei Fain 1956
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Boydaia
Boydaia psalidoprocnei

description: Boydaia psalidoprocnei Fain, 1956
Boydaia psalidoprocnei Fain, 1956b: 650, 660, figs. 22–24, 1963c: 57, figs. 16, 17, 1963d: 56, 67, fig. 27. Holotype in RMCA, examined.
Boydaia (Boydaia) psalidoprocnei, Fain 1971: 100, 109, figs. 26, 27; Pence 1973a: 365. Type host: Psalidoprocne albiceps Sclater (Passeriformes: Hirundinidae) from Rwanda.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Setae vi situated posterior to level of setae si. Sensillae SEd-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–2–0, trochanters 1–1–0–0, femora 5–4–3–3, genua 4–4–3–3, tibiae 5–3–3–3. Setae l' on genu I, d and l' on tibia I eggshaped and dissimilar to other setae of respectively podomer. In larvae, antaxial and paraxial claw pair of leg I subequal, antaxial sharp-ended, paraxial blunt-ended.
Host and distribution. Passeriformes (Hirundinidae): PsalidOprOcne albiceps Sclater from Rwanda [Southern Prov., Akanyaru] (Fain 1956b).
Non-African hosts and distribution. Hirundinidae: Riparia riparia (Linnaeus) from Russia (Zabludovskaya 1998) and Ukraine (Zabludovskaya 2012), Tachycineta bicOlOr (Vieillot) from USA (Pence 1973a).
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 425, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Boydaia pycnonoti Fain 1956
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Boydaia
Boydaia pycnonoti

description: Boydaia pycnonoti Fain, 1956
Boydaia pycnonoti Fain, 1956b: 650, 655, figs. 10–12. Holotype in RMCA, examined. Boydaia (Boydaia) pycnonoti, Fain 1958b: 176, 180, fig. 4, 1963d: 57, 67, 1971: 98, 102, 109, figs. 35–37; Fain et al. 1977: 393.
Type host: Pycnonotus barbatus tricolor (Hartlaub) (Passeriformes: Pycnonotidae) from Rwanda.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Setae vi situated posterior to level of setae si. Sensillae SEa-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–1–0, trochanters 1–1–0–0, femora 7–4–3–3, genua 4–4–3–3, tibiae 5–3–3–3. All setae on genu and tibia of leg I similar in shape. In larvae, antaxial and paraxial claw pair of leg I unequal, both very short and sharp-ended.
Hosts and distribution. Passeriformes (Pycnonotidae): PycnOnOtus barbatus (Desfontaines) from Cameroon [Galim] (Fain et al. 1977) and South Africa [Pretoria, Transvaal] (present paper), P. b. tricOlOr (Hartlaub) from Rwanda [Southern Prov., Akanyaru] (Fain 1956b), P. xanthOpygOs (Hemprich and Ehrenberg) from Kenya [Djaro] (present paper), P. JOcOsus (Linnaeus) from Zimbabwe (present paper).
Non-African hosts and distribution. Pycnonotidae: PycnOnOtus leucOtis (Gould) from India and P. gOiavier persOnatus Hume from Malaysia (Fain 1963d).
New material examined. Three females from PycnOnOtus barbatus (Desfontaines) (Passeriformes: Pycnonotidae), SOUTH AFRICA: Pretoria, Transvaal, 30 December 1969, coll. unknown; 1 female from PycnOnOtus xanthOpygOs (Hemprich and Ehrenberg), KENYA: Djaro, no date, coll. Yunker; 2 females and 3 larvae from PycnOnOtus JOcOsus (Linnaeus), ZIMBABWE (based on host distribution; org. Avicentra): 21 December 1965, coll. unknown. All specimens deposited in the RBINS.
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 425, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Neotyphloceras pardinasii Sanchez & Lareschi 2014
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Hystrichopsyllidae
Neotyphloceras
Neotyphloceras pardinasii

description: Neotyphloceras pardinasii Sanchez & Lareschi, 2014
MLP. Argentina—Chubut: Cañadón de la Madera, Sierra de Tepuel. Mammalia—Rodentia—Cricetidae— Abrothrix hirta. Argentina—Chubut: Estancia El Maitén, Estancia Leleque. Mammalia—Rodentia—Cricetidae— Abrothrix olivacea, Chelemys macronyx, Eligmodontia morgani, Euneomys chinchilloides, Loxodontomys micropus, Phyllotis xanthopygus.
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 243, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Additional file 4: of Comparison of the efficacy and safety of FP-1201-lyo (intravenously administered recombinant human interferon beta-1a) and placebo in the treatment of patients with moderate or severe acute respiratory distress syndrome: study protocol for a randomized controlled trial
Creators: name: Bellingan, Geoff
name: Brealey, David
name: Mancebo, Jordi
name: Mercat, Alain
name: NicolĂ˛ Patroniti
name: PettilĂ¤, Ville
name: Quintel, Michael
name: Jean-Louis Vincent
name: Maksimow, Mikael
name: Jalkanen, Markku
name: Piippo, Ilse
name: V. Ranieri
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Sample Consent Form. (PDF 133Â kb)
Boydaia saxicolae Fain 1969
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Boydaia
Boydaia saxicolae

description: Boydaia saxicolae Fain, 1969
Boydaia saxicolae Fain, 1969: 370, fig. 3, 1971: 98, 102, 108, fig. 4. Holotype in RMCA, examined. Type host: Saxicola torquatus axillaris (Shelley) (Passeriformes: Muscicapidae) from Rwanda.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Setae vi situated posterior to level of setae si. Sensillae SEa-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–1–0, trochanters 1–1–0–0, femora 7–4–3–3, genua 4–4–3–3, tibiae 5–3–3–3. All setae on genu and tibia of leg I similar in shape. Claws of legs I–IV without basal angles. In larvae, antaxial and paraxial claw pair of leg I unequal, antaxial sharp-ended, paraxial blunt-ended.
Hosts and distribution. Passeriformes (Muscicapidae): MOnticOla angOlensis de Sousa from Rwanda [Southern Prov., Akanyaru], MyrmecOcichla nigra (Vieillot) from Rwanda [Southern Prov., Butare], and SaxicOla tOrquatus axillaris (Shelley) from Rwanda [Southern Prov., Butare, Akanyaru and Western Prov., Cyangugu] (Fain 1969).
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 425, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Additional file 2: of Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma
Creators: name: Oduor, Cliff
name: Kaymaz, Yasin
name: Kiprotich Chelimo
name: Otieno, Juliana
name: OngâEcha, John
name: Moormann, Ann
name: Bailey, Jeffrey
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Expression of B-cell differentiation markers and eBL diagnostic surface markers. A) Expression of eBL diagnostic surface markers (CD79, CD10, CD20, and CD19). B) Expression of key transcription factors involved in B-cell differentiation (BLIMP1, IRF4, BCL6 and PAX5). (PDF 106 kb)
Identifier für Forschungsinformationssysteme (FIS) am Beispiel des HeOSP-Verbundes
Creators: name: Abedini, Scholeh
name: Bach, Kerstin
name: Cordes, Birte
name: Demuth, Dominik
name: Hahn, Rebecca
name: Maier, Manuela
name: Seidel, Melanie
name: Schieberle, Andreas
Publisher: name: Zenodo
Year: 2024
Subjects: identifier
CRIS
current research information system
FIS
Forschungsinformationssysteme

description: List of identifiers for use in current research information systems compiled by the HeOSP (Hessische Open Science Portale) - project. Identifiers used by the participants of the HeOSP project are marked with "yes". Identifiers used only by single participants are marked with "teilw." and all identifiers not in use are marked with "no". The list is work in progress.
Boydaia zosteropis Fain 1963
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Boydaia
Boydaia zosteropis

description: Boydaia zosteropis Fain, 1963
Boydaia zosteropis Fain, 1963d: 43, 59, fig. 39, 1970: 320; Domrow 1969: 381. Holotype in RMCA, examined. Boydaia (Boydaia) zosteropis, Fain 1971: 100, 110, fig. 10.
Type host: Zosterops senegalensis stuhlmanni Reichenow (Passeriformes: Zosteropidae) from Rwanda.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Setae vi situated posterior to level of setae si. Sensillae SEa-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–1–1, trochanters 1–1–0–0, femora 6–4–3–2, genua 4–4–3–3, tibiae 5–3–3–3. All setae on genu and tibia of leg I similar in shape. In larvae, antaxial and paraxial claws of leg I long, subequal, and sharp-ended.
Host and distribution. Passeriformes (Zosteropidae): ZOsterOps senegalensis stuhlmanni Reichenow (= Z. s. scOtti) from Rwanda [Eastern Prov., Cyangugu, Rugege forest] (Fain 1963d).
Non-African hosts and distribution. Zosteropidae: ZOsterOps lateralis (Latham) from Australia (Domrow 1969).
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on pages 426-427, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Ctenoparia inopinata Rothschild 1909
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Hystrichopsyllidae
Ctenoparia
Ctenoparia inopinata

description: Ctenoparia inopinata Rothschild, 1909
NHM. Chile—Valparaíso. Mammalia—Rodentia—Cricetidae— Abrothrix olivacea. Chile—Chiloé. Unknown host. Chile; Argentina—Buenos Aires. Neuquén: Parque Nacional Los Arrayanes. Tierra del Fuego, Antártida e Islas del Atlántico Sur: Ushuaia. Río Negro. Mammalia—Rodentia—Cricetidae— Abrothrix hirta, Abrothrix olivacea, Geoxus valdivianus, Loxodontomys micropus, Oligoryzomys longicaudatus. Sanchez et al. (2009), Sanchez & Lareschi (2013).
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 243, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Mahnertellina Kontschán 2020, gen. nov.
Creators: name: Kontschán, Jenő
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Eutrachytidae
Mahnertellina

description: Mahnertellina gen. nov.
Type species: Mahnertellina paradoxa sp. nov.
Diagnosis: Idiosoma yellowish brown, shape triangular, with a pair of long posterior processes. Marginal shield of dorsal idiosoma reduced at level of posterior processes. Peritremes long, anterior part of prestigmatid section of peritremes with some bends. Genital shield of female scutiform. Internal malae on gnathosoma pilose, setae h1 smooth, other setae on gnathosoma serrate. Setae v1 on palp trochanter situated on a long ventral and apically curved process. Adanal setae long and robust.
Etymology: The new genus is dedicated to Professor Volker Mahnert (1943-2018), an excellent pseudoscorpion specialist and a former director of the Natural History Museum in Geneva (Schwendinger, 2019). The gender of the new genus name is feminine.
Notes: Up to now only one genus of the family Eutrachytidae is characterized by long posterior processes of the idiosoma: the genus Dicornutophorus Hirschmann, 1979. This genus possesses a pygidial shield and the marginal shield is complete. These two structures are absent in the new genus. The v1 setae on the palp trochanter of previously described eutrachytid mites is situated on the surface of the trochanter, whereas in the new genus this seta is placed on a long and apically curved process. All previously collected specimens of the genus Dicornutophorus are from the Neotropical region (Bolivia and Brazil; Wiśniewski, 1993), whereas specimens of the new genus and species were found in West Africa.
Zoogeographical note: Till today the African eutrachytids are mostly unknown. The discovery of a second species of this family in Africa indicates that additional closely related species live in the soils of the West African rain forests.
description: Published as part of Kontschán, Jenő, 2020, A second species of the family Eutrachytidae (Acari: Uropodina) in Africa: Mahnertellina paradoxa gen. nov., sp. nov. from the Ivory Coast, pp. 75-81 in Revue suisse de Zoologie 127 (1) on pages 75-76, DOI: 10.35929/RSZ.0007, http://zenodo.org/record/5743545
Additional file 2: of Criteria for prioritization of HIV programs in Viet Nam: a discrete choice experiment
Creators: name: Safarnejad, Ali
name: Pavlova, Milena
name: Vo Son
name: Phuong, Huynh
name: Groot, Wim
Publisher: name: Figshare
Year: 2017
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Contains the survey questionnaire in Vietnamese. (DOCX 481Â kb)
Letter from U.S. Bureau of Mines to Edward F. Grimley requesting to revoke his status as a federal explosives licensing agent
Creators: name: Kanter, F. R.
name: Grimley, Edward F.
Publisher: name: No Publisher Supplied
Year: 1944

description: Dated from March 18, 1944, this letter is addressed to Edward F. Grimley, Assistant City Clerk, South Amboy, New Jersey, from F. R. Kanter, representing R. D. Leitch, Chief of the Explosives Control Division, Bureau of Mines, United States Department of the Interior. Citing the “administration of the Federal Explosives Act”, the letter mentions an initiative to reduce the number of federal explosives licensing agents in practice. Kanter requests that Grimley return his licensing agent certificate of appointment, as well as, all records and supplies related to this position. The letter clarifies that Philip P. Costello, City Clerk of Perth Amboy, will handle federal explosives licenses henceforth.
Boydaia zumpti Fain 1956
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Boydaia
Boydaia zumpti

description: Boydaia zumpti Fain, 1956
Boydaia zumpti Fain, 1955b: 695, 1956a: 43, 47, 50, 1956b: 650, 654, figs. 7–9, 1956c: 32, 1958a: 10, fig. 17, 1963d: 57, 67, fig. 21. Holotype in RMCA, examined.
Boydaia (Boydaia) zumpti, Fain 1971: 100, 109, fig. 34.
Type host: Eurillas latirostris latirostris (Reichenow) (Passeriformes: Pycnonotidae) from Rwanda.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Setae vi situated posterior to level of setae si. Sensillae SEa-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–1–0, trochanters 1–1–0–0, femora 7–4–3–3, genua 4–4–3–3, tibiae 5–3–3–3. All setae on genu and tibia of leg I similar in shape. Claws with basal angles. In larvae, antaxial and paraxial claw pair of leg I unequal, antaxial sharp-ended, paraxial blunt-ended.
Hosts and distribution. Passeriformes (Pycnonotidae): Bleda syndactylus wOOsnami Ogilvie-Grant from unknown locality in Central Africa (Fain 1958a; see remark), Eurillas latirOstris latirOstris (Reichenow) (= E. l. eugenius) from Rwanda [Southern Prov., Akanyaru] (Fain 1956b).
Locustellidae: SchOenicOla brevirOstris alexinae (Heuglin) from Rwanda [Southern Prov., Akanyaru] (Fain 1971).
Remark. This mite species was reported from an individual of Bleda syndactylus wOOsnami died in the Antverpen Zoo (Fain 1958a). This host is distributed in the Central Africa (from east Democratic Republic of the Congo to south Sudan, Kenya, Uganda and Zambia (Clements et al. 2016)).
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 427, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Additional file 2: Table S1. of The effect of long-term confinement and the efficacy of exercise countermeasures on muscle strength during a simulated mission to Mars: data from the Mars500 study
Creators: name: Gaffney, Christopher
name: Fomina, Elena
name: Babich, Dennis
name: Kitov, Vladimir
name: Uskov, Konstantin
name: Green, David
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Plant Biology

description: Multifunctional Dynamometer for Application in Space (MDS) exercise protocol (DOCX 11 kb)
Ctenoparia jordani Smit 1955
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Hystrichopsyllidae
Ctenoparia
Ctenoparia jordani

description: Ctenoparia jordani Smit, 1955
NHM. Argentina—Río Negro: San Carlos de Bariloche. Mammalia—Rodentia—Cricetidae— Oligoryzomys longicaudatus. Chile; Argentina—Neuquén. Mammalia—Rodentia—Cricetidae— Abrothrix olivacea, Akodon sp., Geoxus valdivianus.
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 244, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
NJ Transit response to TEEX after action Report
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2013

description: This document contains a matrix that reviews the observations, recommendations and status for different  improvement categories described in the TEEX after action report. The improvement categories include: communications; critical infrastructure protection; damage assessments and restoration of transportation services; emergency public information; Emergency Operations Center (EOC) management; information sharing; logistical support; organization and planning.
Coboydaia Fain. They 1985
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Coboydaia

description: Genus Coboydaia Fain, 1985
Coboydaya Fain, 1971: 98 (as subgenus of Boydaia), 1985a: 146 (genus rank). Type species: Boydaia trochila Fain, 1958 by original designation.
Diagnosis. Hypostome with 2 pairs of setae. Propodonotal region with 5–6 pairs of setae (ve present or absent). Each agenital and pseudanal setal series with 1–2 pairs. Trochanter I and II without setae.
Remarks. The members of this genus are associated mainly with passerines, however two species have been recorded from non-passeriform host orders: Apodiformes and Columbiformes (Fain et al. 1985; Skoracki et al. 2012). The Afrotropical fauna comprises three of the five described species in this genus: CObOydaia amandavae Fain 1962, C. clavata Fain, 1956, and C. nigra Fain, 1955.
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 427, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Hurricane Sandy rebuilding strategy: Stronger communities, a resilient region
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2013

description: Hurricane Sandy Rebuilding Task Force brought a wide range of stakeholders together to foster innovative ideas and ensure a comprehensive regional approach to rebuilding in the wake of the storm. The task force was charged with identifying and working to remove obstacles to resilient rebuilding while taking into account existing and future risks and promoting the long-term sustainability of communities and ecosystems in the Sandy-affected region. This Rebuilding Strategy establishes guidelines for the investment of the Federal funds made available for recovery and sets the region on a path to being built back smarter and stronger. The report discusses: background on the region, the storm and the recovery; long-term planning for rebuilding; as well as implementation of recovery efforts and monitoring progress.
Langkawiana Ík, 2009, gen. n.
Creators: name: Ík, Jan Šev Č
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Keroplatidae
Langkawiana

description: Langkawiana gen. n.
Type species: Langkawiana maculata sp. n.
Gender: feminine.
Etymology. The generic name is derived from Langkawi Island.
Diagnosis. A relatively small, Macrocera -like fungus gnat with elongated abdomen and narrow wings (Fig. 1). Ocelli absent. Eyes relatively narrow. A large cerebral sclerite, separated from the rest of head by distinct membranous area. The membraneous area continues behind compound eyes. Orbital sclerite well developed. Frons distinct, in the form of a shallow triangular sclerite with median furrow. Palpus five segmented. Palpomeres short, approximately as long as wide. Wing with apical and median dark band. Sc ending free. Radio-median fusion distinct, as long as the stem of M-fork. Basal portion of media developed. Vein R4 absent. A1 weak but reaching wing margin. Tibial trichia arranged in regular rows. Apical spurs on mid and hind tibia strongly reduced, shorter than tibial diameter. Tergite 9 short, transverse. Gonostylus
description: Published as part of Ík, Jan Šev Č, 2009, Langkawiana maculata gen. et sp. n. from Malaysia and its systematic position in the tribe Robsonomyiini (Diptera: Keroplatidae), pp. 58-66 in Zootaxa 2221 on page 59, DOI: 10.5281/zenodo.190100
Ctenoparia propinqua Beaucournu & Gallardo 1988
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Hystrichopsyllidae
Ctenoparia
Ctenoparia propinqua

description: Ctenoparia propinqua Beaucournu & Gallardo, 1988
FMR (MNHN). Argentina—Río Negro: Estación Perito Moreno. Mammalia—Rodentia—Cricetidae— Abrothrix hirta.
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 244, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
State of the climate: New Jersey 2013
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2013

description: State of the Climate: New Jersey provides an overview of recent climate events and trends, their impacts, and their implications for the future of New Jersey. The changes experienced in New Jersey will be examined in the context of human-induced climate change, an important driver of recent and future climate trends. the report begins with a discussion of the state of the climate on a global scale. This is followed by an analysis of local climate trends and recent extreme or unusual events and their impacts. Hurricane Sandy is the most noteworthy of these events, with estimated damages of approximately $50 billion in the region. The implications of future climate change for high-impact events such as Sandy will also be discussed. Sidebars in this report discuss selected impacts of climate change on New Jersey’s residents and resources.
Coboydaia amandavae
Creators: name: Skoracki, Maciej
name: Schmidt, Karl-Heinz
name: Marciniak, Natalia
name: Marciniak, Martyna
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Ereynetidae
Coboydaia
Coboydaia amandavae

description: Coboydaia amandavae (Fain, 1962)
Boydaia amandavae Fain, 1962c: 363, figs. 1–5, 10–14, 1963d: 58, 67, 76, fig. 20, 1970: 319, figs. 19–20. Holotype in RMCA, examined.
Coboydaia amandavae, Fain 1971: 101, 107, 112, figs. 41–43.
Type host: Sporaeginthus subflavus (Vieillot) (Passeriformes: Estrildidae) from Central Africa.
Diagnosis. Hypostome with 2 pairs of setae. Setae ve present. Sensillae SEa-type. Agenital and pseudanal series with 2 pairs of setae, each. Number of leg setae: coxae 2–1–1–0, trochanters 0–0–0–0, femora 6–4–3–1, genua 4– 4–3–2, tibiae 5–3–2–2. In larvae, antaxial and paraxial claws of leg I short, subequal, and sharp-ended.
Host and distribution. Passeriformes (Estrildidae): SpOraeginthus subflavus (Vieillot) from Central Africa (Fain 1962c).
Non-African hosts and distribution. Estrildidae: Amandava amandava (Linnaeus) from Indonesia (Fain 1963d), Erythrura prasina (Sparman) from captivity in Belgium (Fain 1970) but originally distributed in the Oriental region (Clements et al. 2016).
description: Published as part of Skoracki, Maciej, Schmidt, Karl-Heinz, Marciniak, Natalia & Marciniak, Martyna, 2018, A review of mites of the subfamily Speleognathinae (Acariformes: Ereynetidae) parasitizing respiratory tracts of birds in the Afrotropical region, pp. 401-440 in Zootaxa 4403 (3) on page 427, DOI: 10.11646/zootaxa.4403.3.1, http://zenodo.org/record/1212849
Delayed effects of reappraisal, reassurance, and distraction on pain and distress in children undergoing treatment for cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: More than 12,000 children are diagnosed with cancer in the United States each year and the majority of these children will experience pain throughout their illness. Children with cancer are required to undergo repeated invasive medical procedures, including bone marrow aspirations (BMA) and lumbar punctures (LP), which have been described by children as the most distressing and painful aspect of their illness. The experience and memory of procedural pain can have a lasting effect and impact distress in future procedures; children learn to anticipate pain and show increased distress and decreased cooperation at subsequent procedures. Moreover, childhood medical distress has also been linked to adults’ reports of pain and fear around medical events and even avoidance of future health care. Early painful procedures have also been associated with behavioral changes to medical events later in life, a finding that is supported by recent physiological evidence indicating that activation of the pain processing system in the brain can change neuropathways, which leads to increased sensitivity to later stimulation of pain systems. Therefore, it is vital to develop strategies to minimize the pain and distress that children undergo through cancer treatment and understanding the impact of children’s memory on pain is a crucial step in this process. To address this important need, this two-phase application will involve identifying the strategies that children use to cope with distress that promote positive memories of medical events and to understanding how these coping strategies change children’s distress over time during future medical procedures. Specifically, we propose that certain coping strategies will change the way that children interpret stressful medical procedures, which will affect the emotional response to future procedures. These objectives will be accomplished by the following specific aims: Aim 1: Identify emotion-regulation (i.e., coping) strategies that promote more positive memories of distressing medical procedures in children with cancer. Aim 2: Assess the impact of emotion-regulation strategies on children’s distress response to painful procedures over time. This project will provide specific means for impacting children’s pain and distress during medical procedures. Specifically, because the emotion regulation strategies described in this protocol are modifiable and teachable, they provide direct implications for clinical practice in pain management by identifying strategies that can
Resilience. Preparing New Jersey for climate change: a Gap analysis from the New Jersey Climate Adaptation Alliance
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2013

description: This report is an essential step toward the goal of developing policy recommendations to enhance climate change preparedness in New Jersey. It provides context regarding New Jersey’s changing climate and vulnerabilities and summarizes key gaps identified to date through a thorough and ongoing stakeholder outreach process.
Ctenoparia topali Smit 1963
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Hystrichopsyllidae
Ctenoparia
Ctenoparia topali

description: Ctenoparia topali Smit, 1963
NHM. Argentina—Río Negro: El Bolsón. Undetermined rodent (nest). Chile; Argentina—Neuquén. Mammalia— Rodentia—Cricetidae— Abrothrix hirta, Abrothrix olivacea, Loxodontomys micropus, Oligoryzomys longicaudatus.
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 244, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230