cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin-binding protein Drebrin
Creators: name: Willmes, Claudia G.
name: Mack, Till G. A.
name: Ledderose, Julia
name: Schmitz, Dietmar
name: Wozny, Christian
name: Eickholt, Britta J.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Alzheimer's disease
subject: Hippocampus
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The dynamic regulation of the actin cytoskeleton plays a key role in controlling the structure and function of synapses. It is vital for activity- dependent modulation of synaptic transmission and long-term changes in synaptic morphology associated with memory consolidation. Several regulators of actin dynamics at the synapse have been identified, of which a salient one is the postsynaptic actin stabilising protein Drebrin (DBN). It has been suggested that DBN modulates neurotransmission and changes in dendritic spine morphology associated with synaptic plasticity. Given that a decrease in DBN levels is correlated with cognitive deficits associated with ageing and dementia, it was hypothesised that DBN protein abundance instructs the integrity and function of synapses. We created a novel DBN deficient mouse line. Analysis of gross brain and neuronal morphology revealed no phenotype in the absence of DBN. Electrophysiological recordings in acute hippocampal slices and primary hippocampal neuronal cultures showed that basal synaptic transmission, and both long-term and homeostatic synaptic plasticity were unchanged, suggesting that loss of DBN is not sufficient in inducing synapse dysfunction. We propose that the overall lack of changes in synaptic function and plasticity in DBN deficient mice may indicate robust compensatory mechanisms that safeguard cytoskeleton dynamics at the synapse.
The cedar project: using indigenous-specific determinants of health to predict substance use among young pregnant-involved aboriginal women
Creators: name: Shahram, Sana Z.
name: Bottorff, J. L. (Joan L.), 1950-
name: Oelke, Nelly
name: Dahlgren, Leanne
name: Thomas, Victoria
name: Spittal, Patricia M.
Publisher: name: BioMed Central
Year: 2017

description: Background: Indigenous women in Canada have been hyper-visible in research, policy and intervention related to substance use during pregnancy; however, little is known about how the social determinants of health and substance use prior to, during, and after pregnancy intersect. The objectives of this study were to describe the social contexts of pregnant-involved young Indigenous women who use substances and to explore if an Indigenous-Specific Determinants of Health Model can predict substance use among this population. Methods: Using descriptive statistics and hierarchical logistic regression guided by mediation analysis, the social contexts of pregnant-involved young Indigenous women who use illicit drugs’ lives were explored and the Integrated Life Course and Social Determinants Model of Aboriginal Health’s ability to predict heavy versus light substance use in this group was tested (N = 291). Results: Important distal determinants of substance use were identified including residential school histories, as well as protective factors, such as sex abuse reporting and empirical evidence for including Indigenous-specific determinants of health as important considerations in understanding young Indigenous women’s experiences with pregnancy and substance use was provided. Conclusions: This analysis provided important insight into the social contexts of women who have experiences with pregnancy as well as drug and/or alcohol use and highlighted the need to include Indigenous-specific determinants of health when examining young Indigenous women’s social, political and historical contexts in relation to their experiences with pregnancy and substance use.
Crowding, Risk and Homelessness: A Study of Socio-Spatial Relations
Creators: name: Stolz, Paul Nicholas
Publisher: name: Swinburne
Year: 2024

description: This thesis examines residential crowding and the possible risk of homelessness it may pose to young people. When the social and the spatial elements within the research on risks that crowding poses for young people, a more complex picture emerges of the impact of crowding and homelessness. The findings provide a basis for questioning whether a statistical definition of overcrowding as homelessness is adequate or accurate. A more nuanced description of the impact of crowding, the risk it may pose to homelessness and the way this risk may be mitigated are unique contributions of this thesis.
Time-frequency heart rate variability spectral analysis: Effects of unilateral stellate blockade.
Creators: name: Rajagopalan, Kesava C.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Engineering, Biomedical.

description: The Cohen's class of time-frequency spectral analysis distributions are receiving significant attention in the signal processing field because of their appropriateness in analyzing time-varying signals. This work has investigated in detail the application of several Cohen class time frequency distributions to Heart Rate Variability Signals. The clinical application of these tools to these physiological signals has been limited. Using simulated nonstationary and stationary HRV signals, it has been shown that the time-frequency spectral estimators such as smoothed pseudo-Wigner and the exponential distribution offer better performance over the Short Time Fourier Transform in terms of resolution and ability to track the nonstationary behavior or instantaneous frequency if the parameters used in the distributions are carefully chosen. These time-frequency spectral analysis tools have been used as a means to quantify the autonomic tone for seven adults under the effects of right unilateral stellate blockade. The mean peak amplitudes under the predefined low frequency (LF) band (0.05-0.15 Hz) and high frequency band (0.15-0.45 Hz) were computed for pre and post blockade conditions in the supine and standing positions. These results have demonstrated the partial stellate blockade decreased the LF areas by 33% when standing and underlines the importance of efferents from the contralateral and higher cervical ganglia in the control of heart rate. In conclusion, these time-frequency spectral analysis tools will provide the cardiologist with valuable diagnostic, cost effective and noninvasive information about the sympathetic and parasympathetic balance in patients to identify if they are at any medical risk.
ГУМАНИТАРНАЯ НАУКА РУССКОГО ЗАРУБЕЖЬЯ: К 140-летию со дня рождения П.М. Бицилли. Международная конференция в ИМЛИ РАН
Creators: name: Анохина Юлия Юрьевна
Publisher: name: Новый филологический вестник
Year: 2020
Subjects: обзор конференции; русское зарубежье; П.М. Бицилли

description: Предлагается обзор Международной научной конференции «Гуманитарная наука русского зарубежья: К 140-летию со дня рождения П.М. Бицилли». Конференция была организована ИМЛИ им. А.М. Горького РАН при содействии «Дома А.Ф. Лосева – научной библиотеки и мемориального музея» и Дома русского зарубежья им. А. Солженицына и проходила с 18 по 19 ноября 2019 г. Это первое в России научное мероприятие, посвященное ученому, его вкладу в становление исторической науки и в целом в развитие гуманитарной мысли Русского Зарубежья. Петр Михайлович Бицилли (1879–1953) – выдающийся гуманитарий-энциклопедист, создавший фундаментальные работы по теории истории, культурологии, русской литературе, лингвистике. Богатейшее наследие ученого, жившего и работавшего в Болгарии c начала 20-х годов XX столетия, лишь немногим более четверти века назад стало постепенно открываться русскому читателю. Тем не менее, как показала прошедшая конференция, интенсивность научной подготовки трудов Бицилли к изданию и осмысления его работ современными исследователями действительно позволяет говорить об особом направлении гуманитарной мысли, о «бициллиеведении». Цель данного обзора состоит в том, чтобы очертить круг вопросов, на которых было сфокусировано внимание участников конференции. Продемонстрировано, что в центре научной рефлексии докладчиков оказалось большинство научных проблем, являвшихся предметом постоянного интереса Бицилии, среди которых проблемы философского, научно-исторического и филологического характера.
Prototyping real-time multitasking systems.
Creators: name: Junaid, Amjad.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, Electronics and Electrical.

description: Real-time multitasking systems represent a class of complex, dedicated computer systems whose designs require careful analysis and involve several tradeoffs. Two of the main phases in the development of such systems are defining the required functional characteristics of the system, and then translating these requirements into a working design. A substantial amount of progress has been made in systematizing the functional specification phase but the more traditional ad-hoc approach is still largely used in the design phase of these systems. The purpose of this thesis is to show the feasibility of applying development tools and imposing a structured methodology to this design phase of the development process. It is assumed that such a systematic approach to the design phase will reduce development time and cost and result in more reliable and efficient systems. To meet these objectives, this thesis describes the main factors that must be considered in the design of multitasking systems. It also introduces a design prototyping tool that has been specifically designed to gather application specific information pertaining to these factors. Finally, a methodology is proposed that uses this tool to assist in formulating a final design.
A study of sensitivity reduction design approach.
Creators: name: Chandra, Murari.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1970
Subjects: subject: Engineering, Electronics and Electrical.

description: This thesis is concerned with the reduction of sensitivity in Linear Optimal Control Systems. The classical concept of Sensitivity and the important results, in context of modern Control Theory have been summarized. The potentials of adding the sensitivity terms in the quadratic performance index for the reduction of the Plant Sensitivity to small parameter perturbations have been investigated. Some design criteria and theoretical results in the role of weighting matrices, that are significant in the Sensitivity Reduction Design approaches have also been presented.
ИТАЛЬЯНИСТИКА В СОВРЕМЕННОМ МИРЕ
Creators: name: Быстрова Татьяна Александровна
name: Смирнова Мария Александровна
Publisher: name: Новый филологический вестник
Year: 2020
Subjects: итальянистика; романская филология; перевод; диалектология; история языка; дидактика; литературоведение; социолингвистика

description: Предлагаемый реферативный обзор посвящен Второй международной научно-практической конференции «Итальянистика в современном мире», которая прошла 27–28 февраля 2020 г. в Институте иностранных языков Московского городского педагогического университета. В конференции, организованной кафедрой романской филологии ИИЯ МГПУ, приняли участие видные ученые-итальянисты, профессора ведущих университетов России и Италии, переводчики художественной прозы и поэзии, аспиранты и молодые преподаватели, а также представители международной общественности в лице посла Итальянской республики в РФ г-на Паскуале Терраччано и директора Итальянского института культуры в Москве г-жи Луиджины Педди. Выступления докладчиков объединяют следующие тематические блоки: история итальянской литературы и перевод, история и культура Италии, преподавание итальянского языка и других предметов итальянистики. Представленные на конференции доклады были посвящены широкому спектру вопросов, от дидактики итальянского языка до культурно-языковой прагматики, аспектов изучения итальянских диалектов и миноритарных языков в оптике лингвистического законодательства и задач, встающих перед современным исследователем итальянской литературы и переводчиком. Участники отметили острую актуальность заявленной проблематики и высокий уровень дискуссии. Также в рамках конференции состоялся конкурс студенческих выступлений, позволивший самым молодым докладчикам сделать первые шаги в филологической науке и получить опыт публичного научного высказывания.
"Women play sports (just not as well)": Canadian newspapers' coverage of men's and women's sports at the 1999 Pan-American Games.
Creators: name: Mason, Frederick Daniel.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Canadian Studies.

description: This study examined English language Canadian newspapers' coverage of the 1999 Pan-American Games that were held in Winnipeg, Manitoba. Using a methodology that borrowed from the Ricoeurian approach to hermeneutics, a comparison between the coverage of men's and women's sports in five newspapers was made. The study focused on emergent themes in the coverage of men's and women's sports, as well as the identification of descriptors used for men and women athletes. A structural analysis of the text was also made, which included a comparison on the percentage of articles, the percentage of headlines, the percentage of photographs, and the estimated size of articles and photographs. Photographs were also considered a part of the text, and were analyzed in terms of both content and context. Structural results are that women received almost equitable coverage, especially when considered in light of participation rates at the Games. Themes and descriptors of both men and women focused on such things as physicality, emotionality, personality issues, and family life. However, there were differences within the categories of themes that created an image of women athletes who were less experienced and successful in sport, and more emotional than men. Male athletes, by comparison, were presented as more violent, more experienced, and able to be successful in other masculine roles. There was evidence of practices such as ambivalence, infantilization and sexualization towards the women athletes. In conclusion, the study indicate that while women are getting more coverage than ever before, many media practices that marginalize women in sport and set sport off as a male preserve still occur, only they have become more subtle.
EMS-witnessed cardiac arrest: Descriptive epidemiology, predictors of survival, and survival comparison with bystander-witnessed cardiac arrest.
Creators: name: De Maio, Valerie Jill.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Health Sciences, Medicine and Surgery.

description: Statement of the problem. Cardiac arrest is the leading cause of death in Canada, yet it remains a problem with extremely poor prognosis. The prehospital response to cardiac arrest is critical since the majority of these events occur in the community, prior to the patient being transported to hospital. Cardiac arrests that occur after the arrival of trained emergency medical services (EMS) personnel (either ambulance or firefighters) may be a particularly homogeneous subgroup in which to assess not only mechanisms of cardiac arrest, but also the effectiveness of prehospital systems, and thereby contribute to our current understanding of the cardiac arrest condition. Objectives. The objectives of this study are threefold: (1) to elucidate the epidemiology of EMS-witnessed cardiac arrest in Ontario in terms of demographics, EMS-system and clinical characteristics, and rates of incidence and survival; (2) to determine predictors of survival to hospital discharge in this group; and (3) to compare outcomes among EMS-witnessed and bystander-witnessed cardiac arrest. (Abstract shortened by UMI.)
Standard Model Precision Measurements with two Z bosons and two jets in ATLAS.
Creators: name: Bhattarai, Prajita
Publisher: name: Brandeis University
Year: 2023

description: This thesis presents the differential cross-section measurements as a function of several kinematic observables, sensitive to vector boson scattering for two Z bosons production in association with two jets ($ZZ^*jj$), where each $Z$ boson is reconstructed in same-flavor opposite-charge two leptons final state. The electroweak $ZZ^*jj$ production includes the rare triple and quartic self-couplings of gauge bosons, whose scattering amplitude at high energies is regularized by the Standard Model $H\rightarrow ZZ^{*}$ processes. The analysis is performed using the proton-proton collision data collected by the ATLAS experiment during LHC Run-2 at $\sqrt{s}=13$ TeV center-of-mass collision energy, corresponding to an integrated luminosity of $139~fb^{-1}$. Several theories Beyond the Standard Model are expected to modify the electroweak $ZZ^*jj$ cross-sections at high energies. Certain phase space of some kinematic observables describing the electroweak $ZZ^*jj$ process is sensitive to these new physics modifications. Therefore, performing differential cross-section measurements as a function of these kinematic observables for the electroweak $ZZ^*jj$ processes is crucial. Given the low statistics in Run-2, the cross-sections corrected for detector effects are measured in an electroweak-enhanced phase space and compared to the state-of-the-art Standard Model predictions. The differential cross-sections are also used to constrain anomalous quartic gauge couplings using a dimension-8 Effective Field Theory formalism.
The Duality of Economic Issues with Medication Non-Adherence in Patients with Inflammatory Arthritis
Creators: name: Campbell, Natasha K. J.
name: Saadeldin, Khalid
name: De Vera, Mary
Publisher: name: The University of British Columbia
Year: 2018

description: Purpose of Review: In this review, we synthesize current data on non-adherence across inflammatory arthritides and explore 1) the effects of economic factors on non-adherence and 2) the impacts of non-adherence on economic outcomes. Recent findings: Recent evidence demonstrates medication non-adherence rates as high as 74% in ankylosing spondylitis (AS), 90% in gout, 50% in psoriatic arthritis (PsA), 75% in systemic lupus erythematosus (SLE), and 82% in rheumatoid arthritis (RA). Summary: The effects of socioeconomic factors have been studied most in RA and SLE but with inconsistent findings. Nonetheless, the evidence points to having prescription coverage and costs of treatment as important factors in RA and education as an important factor in SLE. Limited data in AS and gout, and no studies of the effects of socioeconomic factors in PsA, show knowledge gaps for future research. Finally, there is a dearth of data with respect to the impacts of non-adherence on economic outcomes.
REDUCING MELOIDOGYNE HAPLA (NORTHERN ROOT-KNOT NEMATODE) USING COVER CROPS, FALLOW PERIODS AND VITIS SPP. ROOTSTOCKS
Creators: name: Gagnier, Bernadette Kristine
Publisher: name: Washington State University
Year: 2024
Subjects: grape
Meloidogyne hapla
Nematode
vineyard
Vitis vinifera
Agriculture

description: Non-chemical strategies for plant parasitic nematode management allow for the development of alternative integrated pest management strategies. Cover crops, fallow periods and Vitis spp. rootstocks are such strategies, and were evaluated for their ability to reduce soil-borne Meloidogyne hapla (northern root-knot nematode). This nematode is the primary plant parasitic nematode of concern in Washington’s own-rooted Vitis vinifera vineyards. Cover crops were evaluated both in pre-plant and post-plant vineyard scenarios. In pre-plant scenarios, litchi tomato (Solanum sisymbriifolium) was evaluated as previous studies against other nematode species demonstrated its efficacy. In this study, litchi tomato was able to significantly reduce the population density of M. hapla in the soil relative to a weedy fallow pre-plant ground cover. ‘Dracula’ oilseed radish (Raphanus sativus), ‘Pacific Gold’ mustard (Brassica juncea) and ‘Dutch White’ clover (Trifolium repens) were evaluated as cover crops for post-plant management of M. hapla. While all three crops reduced M. hapla populations relative to weedy fallow ground cover in field studies, ‘Dracula’ oilseed radish reduced M. hapla populations most significantly. A survey of fallow sites across eastern Washington, which were previously planted to V. vinifera, showed that a period of fallow for at least one calendar year was needed to reduce populations densities of M. hapla in the soil. Other management strategies that were applied to these sites during their fallow period, such as the use of cover crops, irrigation, herbicide, or tillage during the fallow period did not significantly reduce M. hapla populations. Finally, Vitis spp. rootstocks were evaluated in greenhouse experiments. Nine different Vitis spp. rootstocks were assessed for their ability to host M. hapla, and own-rooted V. vinifera ‘Cabernet Sauvignon’ and ‘Chardonnay’ served as susceptible controls. While all non-vinifera rootstocks hosted statistically fewer M. hapla than the V. vinifera controls, the non-vinifera rootstocks were not entirely immune from nematode feeding and reproduction. Short-term greenhouse experiments can be useful in evaluating the ability of nematodes to feed and reproduce on a genotype but cannot determine if feeding will result in a change in phenotype (i.e., reduced growth or yield) over the lifespan of a vineyard.
description: Individually, the adoption of a cover crop, the use of a fallow period between vineyard replanting, or the adoption of a rootstock might not provide complete mitigation of M. hapla damage to grapevines. However, when combined, they have the potential to provide effective, long-term, non-chemical management of this plant parasitic nematodes in vineyards.
УСАДЬБА И ДАЧА – ПАНОРАМНЫЙ ОХВАТ И ГЛУБИНА ПОСТИЖЕНИЯ Рецензия на книгу: Богданова О.А. Усадьба и дача в русской литературе XIX–XXI вв.: топика, динамика, мифология: Монография. М.: ИМЛИ РАН, 2019. 288 с. (Сер. «Русская усадьба в мировом контексте». Вып. 1)
Creators: name: Доманский Юрий Викторович
Publisher: name: Новый филологический вестник
Year: 2020
Subjects: русская литература; усадьба; дача; усадебный топос; усадебный миф; дачный топос

description: В рецензии представлена книга, которую с полным правом можно признать этапной в изучении усадебного и дачного топосов в русской литературе за более чем два столетия их, этих топосов, существования. В рецензии показывается, как автору монографии удается уточнить ряд базовых для решаемой проблемы терминов – обрисовываются семантические поля «усадебного текста» и «усадебной культуры», отграничиваются друг от друга понятия «усадебный миф», «усадебный хронотоп», «усадебный локус», «усадебный топос», «поэтосфера усадьбы», «дачный топос» и др., вводятся категории «гетеротопия усадьбы» и «усадебный габитус». Автор рецензируемой монографии на обширном материале убедительно доказывает универсальность и междисциплинарность названных терминов. В рецензии подробно описывается структура монографии, а через это демонстрируется, как на многочисленных примерах из конкретных произведений (в монографии рассматриваются произведения Ф.М. Достоевского, А.Н. Толстого, А.М. Горького, И.С. Тургенева, Н.С. Гумилёва, И.А. Бунина, М.М. Пришвина, М.А. Булгакова, В.О. Пелевина, В.Г. Сорокина, Е.Г. Водолазкина и многих других) автор книги утверждает свою концепцию, согласно которой ключевой категорией для научного осмысления феномена усадьбы в литературе оказывается понятие усадебного топоса. Автор рецензии настаивает на том, что монография О.А. Богдановой может служить энциклопедией усадебного и дачного текстов от позапрошлого века и почти до наших дней, а вбирая в себя всю предшествующую исследовательскую традицию по данной проблеме, еще и формирует дальнейшие пути, указывает грядущим исследователям направление последующего движения, системно и многогранно осмысливая изображение усадьбы и дачи в русской литературе.
ПЛАТОНОВ – НАШ ТОВАРИЩ Рецензия на книгу: Малыгина Н.М. Андрей Платонов и литературная Москва: А.К. Воронский, А.М. Горький, Б.А. Пильняк, Б.Л. Пастернак, Артем Веселый, С.Ф. Буданцев, В.С. Гроссман. М.; СПб.: Нестор-История, 2018. 590 с., ил.
Creators: name: Овчаренко Алексей Юрьевич
Publisher: name: Новый филологический вестник
Year: 2020
Subjects: Платонов; Буданцев; Весёлый; Воронский; Горький; Гроссман; Пильняк; Пастернак; литературные связи; творческие контакты; литературный процесс.

description: В рецензии на монографию ведущего исследователя творчества А.П. Платонова, известного специалиста по русской литературе 1920–1930-х годов Н.М. Малыгиной «Андрей Платонов и литературная Москва: А.К. Воронский, А.М. Горький, Б.А. Пильняк, Б.Л. Пастернак, Артем Веселый, С.Ф. Буданцев, В.С. Гроссман» определены методологические принципы анализа писательской биографии А.П. Платонова, рассмотренной в контексте литературного процесса 1920–1940-х годов. Установлено, что исследование проводилось путем сочетания контекстуального, мотивного, «генетического» методов анализа литературного процесса 1920–1940-х годов и произведений советских писателей 1920–1940-х годов, с творчеством которых сопоставляются тексты А.П. Платонова. Рецензия ставит проблему изучения московского литературного окружения и творческих связей А. Платонова. Раскрывается новизна исследования Н.М. Малыгиной, состоящая в том, что московские связи писателя выявлены задолго до начала московского периода его жизни и творчества. Раскрывается своеобразие рецензируемой монографии, обусловленное сочетанием исследования в хронологическом порядке ключевых событий литературного процесса 1920–1940-х годов, в которых принимал участие А. Платонов, с глубоким анализом поэтики произведений А. Воронского, М. Горького, Б. Пильняка, Б. Пастернака, Артема Веселого, С. Буданцева, В. Гроссмана. Устанавливая характер его участия в событиях литературной жизни столицы, исследователь в каждой главе монографии анализирует поэтику его произведений в контексте советской литературы 1920–1940-х годов. В монографии в процессе анализа событий московской литературной жизни выявляются творческие связи А.П. Платонова с писателями-современниками. В книге Н.М. Малыгиной исследование московского литературного окружения А.П. Платонова не ограничивается выявлением личных контактов и творческих связей писателя с его современниками. В рецензии ставится проблема необходимости систематизации фактов литературной жизни, выявления их причинноследственных связей в осмыслении контекстов и процесса творчества. Показано, что особая ценность исследования состоит в обращении к архивным материалам, представленным впервые. Это документы, дополняющие сведения о биографии и творческом наследии Воронского, материалы из архива А.М. Горького, материалы из архива С.Ф. Буданцева, тексты писем В.С. Гроссмана, сверенные с автографами, хранящимися в РГАЛИ.
3251051.pdf
Creators: name: Hallett, Dominic
name: Foster, Andrew
name: Hurst, David
name: Royall, Ben
name: Kok, Pieter
name: Clarke, Edmund
name: Itskevich, Igor
name: Fox, A. Mark
name: Skolnick, Maurice
name: Wilson, Luke
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary figures and theory.
Valvopatias: da prática clínica ao manejo imediato
Creators: name: Renato Júnior Xavier
Publisher: name: Zenodo
Year: 2024

description: As valvopatias representam um conjunto de doenças que afetam as válvulas cardíacas, resultando em distúrbios funcionais que variam desde estenoses até insuficiências. A abordagem clínica dessas condições exige um diagnóstico rápido e preciso, seguido de um manejo terapêutico imediato para evitar complicações graves, como insuficiência cardíaca e morte súbita. Este artigo revisa as principais valvopatias, abordando a prática clínica, o diagnóstico, e as opções de manejo imediato, com ênfase na importância de uma intervenção precoce. A revisão integrativa é baseada em estudos recentes, enfatizando a necessidade de estratégias personalizadas que considerem a gravidade da doença e as condições clínicas de cada paciente.
L'évaluation des arguments selon S. E. Toulmin.
Creators: name: Beauparlant, Roch.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Philosophy.

description: Toulmin adopte une perspective logique de l'etude des arguments (comparativement a une perspective rhetorique ou dialectique). Mais son approche se saurait en aucun cas etre assimilee a celle de la logique formelle. Aussi, l'une de mes premieres taches sera de presenter sa conception de la logique qui, par son originalite, diverge sensiblement du traitement reserve aux arguments par la logique formelle. Cela dit, l'approche de Toulmin apparai t egalement d'inspiration dialectique (bien que ce mot ne se trouve nulle part dans ses ecrits.) En somme, Toulmin propose une methodologie nouvelle pour la description et l'evaluation des arguments. On en arrive ainsi a une double caracterisation de l'approche toulminienne: Logique. (1) emploi de criteres logiques derives de nos pratiques argumentatives reelles (et non poses a priori, issus du paradigme analytique) ..., Dialectique. (2) ... servant a la critique rationnelle des arguments, selon une methode inspiree de l'echange dialectique (ensemble de questions critiques). Dans cet ouvrage, il sera question: (A) Des deux conceptions de la logique (opposition des points de vue); (B) Des deux modeles methodologiques qui sous-tendent les deux conceptions (opposition des modeles/details du fonctionnement); (C) Du cadre general dans lequel s'inscrit l'approche. (Abstract shortened by UMI.)
Capacity building and training approaches for water safety plans: A comprehensive literature review
Creators: name: Ferrero, Giuliana
name: Rickert, Bettina
name: Setty, Karen
Publisher: name: My University
Year: 2019
Subjects: Kapazitätsaufbau (Fähigkeiten)
Ausbildung
Trinkwasser
Wasserversorgung

description: The World Health Organization has recommended Water Safety Plans (WSPs), a holistic risk assessment and risk management approach, for drinking-water suppliers across low-, middle- and high-income countries, since publishing its 2004 Guidelines for Drinking-Water Quality. While rapid WSP adoption has occurred, capacity is still catching up to implementation needs. Many countries and regions lack case examples, legal requirements, and training resources for WSPs, corresponding to widespread capacity shortfall in the water supply sector. We undertook a comprehensive review of the literature on capacity building and training for WSPs, with the goal of providing recommendations for multiple stakeholder groups at the scales of individual utilities, national governments, and intermediate units of governance. We propose a WSP training taxonomy and discuss it in relation to the stages of learning (introduction, practice, and reinforcement); describe the importance of customizing training to the target group, local language and circumstances; highlight the relevance of auditing for evaluating change over time; and call for robust methods to monitor WSP capacity development. © 2019 World Health Organization. Published by Elsevier
GNOSIS: A novel near-infrared OH suppression unit at the AAT
Creators: name: Trinh, C. Q.
name: Ellis, S. C.
name: Lawrence, J. S.
name: Horton, A. J.
name: Bland-Hawthorn, J.
name: Leon-Saval, S. G.
name: Bryant, J.
name: Case, S.
name: Colless, M.
name: Couch, Warrick
name: Freeman, K.
name: Gers, L.
name: Glazebrook, Karl
name: Haynes, R.
name: Lee, S.
name: Löhmannsröben, H. G.
name: Miziarski, S.
name: O'Byrne, J.
name: Rambold, W.
name: Roth, M. M.
name: Schmidt, B.
name: Shortridge, K.
name: Smedley, S.
name: Tinney, C. G.
name: Xavier, P.
name: Zheng, J.
name: McLean, Ian S.
name: Ramsay, Suzanne K.
name: Takami, Hideki
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: GNOSIS has provided the first on-telescope demonstration of a concept to utilize complex aperioidc fiber Bragg gratings to suppress the 103 brightest atmospheric hydroxyl emission doublets between 1.47-1.7 μm. The unit is designed to be used at the 3.9-meter Anglo-Australian Telescope (AAT) feeding the IRIS2 spectrograph. Unlike previous atmospheric suppression techniques GNOSIS suppresses the lines before dispersion. We present the results of laboratory and on-sky tests from instrument commissioning. These tests reveal excellent suppression performance by the gratings and high inter-notch throughput, which combine to produce high fidelity OH-free spectra.
The effects of a family-based intervention on regimen adherence and metabolic control of adolescents with IDDM: A randomized controlled outcome study.
Creators: name: Coupland, Karen J.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Health Sciences, Medicine and Surgery.

description: Patients with insulin-dependent diabetes mellitus (IDDM) must adhere to a complex treatment regimen. Adherence is often poor during adolescence, when the regimen behaviours may interact negatively with many of the developmental tasks. In a randomized controlled outcome study, 15 adolescents and their families participated in a family-based intervention for improving adherence to the diabetic regimen. Fourteen comparison group adolescents with IDDM spent a comparable amount of time learning stress management techniques. Adolescents in both groups attended a diabetes management review session with the clinic nurse. Inclusion criteria included mean glycosylated hemoglobin (HbAlc) levels $>$9.0% over the previous nine months. At a 6-month follow-up, adolescents in the family intervention group were testing blood glucose levels more regularly (p $$1% (0% vs. 29%, $\chi\sp2$ = 6.32, p =.05). Methodological issues were discussed.
3251051.pdf
Creators: name: Hallett, Dominic
name: Foster, Andrew
name: Hurst, David
name: Royall, Ben
name: Kok, Pieter
name: Clarke, Edmund
name: Itskevich, Igor
name: Fox, A. Mark
name: Skolnick, Maurice
name: Wilson, Luke
Publisher: name: Optica Publishing Group
Year: 2018
Subjects: Uncategorized

description: Supplementary figures and theory.
Fate and behavior of 14C-labelled ionic compounds in a soil simulation test
Creators: name: Ackermann, Juliane
name: Claßen, Daniela
name: Schäffer, Andreas
Publisher: name: My University
Year: 2021

description: The influence of an ionic functional group on the fate and behavior of chemicals in the environment has so far not been systematically investigated. This study, therefore, examines the following three substances with high structural similarity but differing charge: non-charged 4-n-dodecylphenol[phenylring-14C(U)] (14C-DP), negatively charged 4-n-dodecylbenzenesulfonicacid[phenylring-14C(U)] sodium salt (14C-D-) and positively charged 4-n-dodecylbenzyltrimethylammonium chloride[phenylring-14C(U)] (14C-DA+). They were investigated in a soil simulation study according to the OECD 307 test guideline by measuring the distribution of the applied radioactivity (AR) among volatile, mineralized, extractable and non-extractable residues (NER) in one soil after 0, 1, 7, 14, 49, 84 and 124 days of incubation. Extractable portions of 14C were examined by means of radio-TLC and -HPLC analyses. Microbial activity of the soil incubated with and without 14C-DP, 14C-DS- and 14C-DA+ was determined measuring the reduction of dimethylsulfoxide (DMSO) over time. After 124 days of incubation highest mineralization could be observed for 14C-DS- (64.5% AR). Except CO2, no volatile residues were formed over time. Besides the parent compounds, polar (14C-DP, 14C-DS- and 14C-DA+) and nonpolar (14C-DA+) transformation products were detected. Highest amounts of 14C were extracted using methanol and were thus potentially bioavailable for soil microorganisms. Microbial activity was markedly higher in soil incubated with 14C-DP and 14C-DS- compared to 14C-DA+ or soil without any treatment. Half-lives (DT50 k2) at 18 ËÌC were as follows: DA+ (61.8 days) > DS- (18.2 days) > DP (10.0 days). In case of the cationic compound and its transformation products we conclude that a higher sorption affinity to soil particles leads to reduced bioavailability for microorganisms and thus reduced mineralization resulting in a higher persistence compared to anionic and non-charged organic compounds in soil. The impact of our findings on the persistence assessment of chemicals when performing OECD guideline tests in soil, water-sediment and surface water is discussed. © 2021 Published by Elsevier B.V.
Leucemia mieloide aguda: diagnóstico precoce e propedêuticas
Creators: name: Renato Júnior Xavier
Publisher: name: Zenodo
Year: 2024

description: A leucemia mieloide aguda (LMA) é uma neoplasia hematológica agressiva, caracterizada pela proliferação clonal descontrolada de células progenitoras mieloides imaturas na medula óssea. O diagnóstico precoce é crucial para melhorar os resultados clínicos, uma vez que a LMA pode progredir rapidamente, levando à falência medular e morte. Este artigo revisa as características clínicas, métodos diagnósticos e abordagens propedêuticas da LMA, com base em literatura atualizada. Conclui-se que a LMA requer um diagnóstico imediato, seguido de uma avaliação minuciosa dos achados clínicos e laboratoriais para iniciar o tratamento adequado em tempo hábil, visando a melhora do prognóstico e da sobrevida dos pacientes.
3254465.pdf
Creators: name: Wood, Michael
name: Campione, Salvatore
name: Parameswaran, S
name: Luk, Ting S. Willie
name: Wendt, Joel
name: Serkland, Darwin Keith
name: Keeler, Gordon
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental measurement results
Reentrant metal-insulator transitions in silicon-MOSFETs.
Creators: name: Campbell, John William M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Physics, Condensed Matter.

description: This thesis describes a study of reentrant metal-insulator transitions observed in the inversion layer of extremely high mobility Si-MOSFETs. Magneto-transport measurements were carried out in the temperature range 20mK-4.2 K in a $\sp3$He/$\sp4$He dilution refrigerator which was surrounded by a 15 Tesla superconducting magnet. Below a melting temperature $(T\sb{M}\sim500$ mK) and a critical electron density $(n\sb{s}\sim9\times10\sp $ cm$\sp{-2}),$ the Shubnikov-de Haas oscillations in the diagonal resistivity enormous maximum values at the half filled Landau levels while maintaining deep minima corresponding to the quantum Hall effect at filled Landau levels. At even lower electron densities the insulating regions began to spread and eventually a metal-insulator transition could be induced at zero magnetic field. The measurement of extremely large resistances in the milliKelvin temperature range required the use of very low currents (typically in the $10\sp{-12}$ A range) and in certain measurements minimizing the noise was also a consideration. The improvements achieved in these areas through the use of shielding, optical decouplers and battery operated instruments are described. The transport signatures of the insulating state are considered in terms of two basic mechanisms: single particle localization with transport by variable range hopping and the formation of a collective state such as a pinned Wigner crystal or electron solid with transport through the motion of bound dislocation pairs. The experimental data is best described by the latter model. Thus the two dimensional electron system in these high mobility Si-MOSFETs provides the first and only experimental demonstration to date of the formation of an electron solid at zero and low magnetic fields in the quantum limit where the Coulomb interaction energy dominates over the zero point oscillation energy. The role of disorder in favouring either single particle localization or the formation of a Wigner crystal is explored by considering a variety of samples with a wide range of mobilities and by varying the ratio of the carrier density (controlled by the applied gate voltage) to the impurity density (fixed during sample growth). A phase diagram showing the boundaries between the two dimensional electron gas, the Wigner solid, and the single particle localization induced insulator is established in terms of carrier density and sample mobility.
The effect of audiovisual tape self-confrontation on the self-concept of high-anxiety twelfth-grade students within a client-centered counseling situation.
Creators: name: Crowder, Thomas H.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1978
Subjects: subject: Education, Guidance and Counseling.

description: The problem of this study was to determine the effect of varying degrees of intensity of audiovisual tape self-confrontation upon the self-concept of high anxiety twelfth-grade students in a group counseling situation under client-centered conditions. The general hypothesis was that, if audiovisual self-confrontation is used in client-centered group counseling, then significantly higher scores will result on a measure of self-concept than if such confrontation is not used. The study was based upon the premise that audiovisual self-confrontation represents a unique adjunct to the techniques of client-centered therapy in providing to the client an objective view of his own behavior as well as the reactions of others to his behavior. By providing this view, the confrontation is supportive of the self-perception purpose of therapeutic techniques. It tests the client-centered theory assertions that (1) one of the objectives of therapy is to help the client differentiate and discriminate the objects of his feelings and perceptions, including his self, thereby bringing about a more positive self-concept, and (2) if incongruence exists, a sudden or obvious demonstration of the incongruence may result in a deteriorated self-concept. In order to test the effect of audiovisual self-confrontation, high anxiety twelfth-grade students were assigned randomly to two groups of six students in each of five high schools. In each group, students were designated randomly, two for focused self-confrontation (with discussion), two for unfocused self-confrontation (without discussion), and two for no self-confrontation as control. Following a twenty-five-minute client-centered group counseling session (with self-confrontation for designated students) each week over a six-week period, students were tested on the self-concept variable. The results did not support the hypothesis that audiovisual self-confrontation would enhance the self-concept. There was no statistically significant difference between the self-concept scores of the focused, unfocused, and control groups of students. Therefore, both Hypothesis 1 and Hypothesis 2 were rejected. The results of the study did indicate that, for the students involved under the given conditions, audio-visual self-confrontation was not effective as an adjunct in the implementation of client-centered therapy.
Towards Understanding Microbes Involved in Microbiologically Influenced Corrosion in the Marine Environment
Creators: name: Phan, Hoang
Publisher: name: Swinburne
Year: 2024

description: Microbiologically influenced corrosion (MIC), the deterioration of metals as a result of the metabolic activities of microorganisms, involves complex microbial communities. This thesis explored a particular form of MIC called accelerated low water corrosion (ALWC), which affects metallic structures in marine environments, particularly around the low tide water level. This research has led to a better understanding of the spatial variation of microbial communities relevant to ALWC and the microbes that are being enriched in test kits commonly used in the field to help identify MIC/ALWC. Work has also started on the use specific combinations of microbes from the culture collection of 187 isolates obtained, with the aim of producing more realistic laboratory-based corrosion tests.
Beyond NDVI : Developing a Natural Space Index for Population-Level Health Research
Creators: name: Rugel, Emily J.
name: Henderson, Sarah B.
name: Carpiano, Richard M.
name: Brauer, Michael (Of University Of British Columbia)
Publisher: name: Elsevier
Year: 2023

description: Background: Natural spaces can provide psychological benefits to individuals, but population-level epidemiologic studies have produced conflicting results. Refining current exposure-assessment methods is necessary to advance our understanding of population health and to guide the design of health-promoting urban forms. Objectives: The aim of this study was to develop a comprehensive Natural Space Index that robustly models potential exposure based on the presence, form, accessibility, and quality of multiple forms of greenspace (e.g., parks and street trees) and bluespace (e.g., oceans and lakes). Material and methods: The index was developed for greater Vancouver, Canada. Greenness presence was derived from remote sensing (NDVI/EVI); forms were extracted from municipal and private databases; and accessibility was based on restrictions such as private ownership. Quality appraisals were conducted for 200 randomly sampled parks using the Public Open Space Desktop Appraisal Tool (POSDAT). Integrating these measures in GIS, exposure was assessed for 60,242 postal codes using 100- to 1,600-meter buffers based on hypothesized pathways to mental health. A single index was then derived using principal component analysis (PCA). Results: Comparing NDVI with alternate approaches for assessing natural space resulted in widely divergent results, with quintile rankings shifting for 22-88% of postal codes, depending on the measure. Overall park quality was fairly low (mean of 15 on a scale of 0-45), with no significant difference seen by neighborhood-level household income. The final PCA identified three main sets of variables, with the first two components explaining 68% of the total variance. The first component was dominated by the percentages of public and private greenspace and bluespace and public greenspace within 250 meters, while the second component was driven by lack of access to bluespace within 1 kilometer. Conclusions: Many current approaches to modeling natural space may misclassify exposures and have limited specificity. The Natural Space Index represents a novel approach at a regional scale with application to urban planning and policy-making.