cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Improving Monthly Fed Cattle Forecasts with Information on Market-Ready Inventory
Creators: name: McDaniel, Kendall L.
name: Koontz, Stephen R.
name: McDaniel, Kendall L.
name: Koontz, Stephen R.
Publisher: name: Unknown
Year: 1996
Subjects: Agricultural marketing

description: Market-ready inventories are cattle which have reached an adequate degree of feeding finish but which have not been sold. The level of market-ready inventories appear to have an important impact on fed cattle prices, are discussed in industry and outlook publications, but have not been used in fed cattle price models. This work finds that incorporating measures of market-ready inventories into autoregressive models of monthly fed cattle prices will improve explanatory power but not the forecast performance of these models. Public data are insufficient for forecasting over this time horizon.
Optimization with Equality and Inequality Constraints Using Parameter Continuation
Creators: name: Li, Mingwu
name: Dankowicz, Harry
Publisher: name: arXiv
Year: 2019
Subjects: subject: Optimization and Control (math.OC)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: We generalize the successive continuation paradigm introduced by Kernévez and Doedel [16] for locating locally optimal solutions of constrained optimization problems to the case of simultaneous equality and inequality constraints. The analysis shows that potential optima may be found at the end of a sequence of easily-initialized separate stages of continuation, without the need to seed the first stage of continuation with nonzero values for the corresponding Lagrange multipliers. A key enabler of the proposed generalization is the use of complementarity functions to define relaxed complementary conditions, followed by the use of continuation to arrive at the limit required by the Karush-Kuhn-Tucker theory. As a result, a successful search for optima is found to be possible also from an infeasible initial solution guess. The discussion shows that the proposed paradigm is compatible with the staged construction approach of the COCO software package. This is evidenced by a modified form of the COCO core used to produce the numerical results reported here. These illustrate the efficacy of the continuation approach in locating stationary solutions of an objective function along families of two-point boundary value problems and in optimal control problems.
Options Portfolios in the Presence of Non-Linear Risk
Creators: name: McNew, Kevin
name: McNew, Kevin
Publisher: name: Unknown
Year: 1996
Subjects: Agricultural marketing

description: Options on futures give hedgers a way to construct a risk management portfolio which has similar properties to the risk they face in the cash market. Of particular importance is the benefit that options provide when the cash position value is non-linearly related to the futures price. Such a situation is particularly prevalent for grain producers who face random cash prices and output. This study presents two methods for constructing an options portfolio composed of different strike prices. An empirical application for regional corn production in the U.S. demonstrates that both methods are similar in terms of risk reduction and, in some instances, provided significant improvements from using futures.
MOESM1 of Gut bacteria of weevils developing on plant roots under extreme desert conditions
Creators: name: Fengqun Meng
name: Nitsan Bar-Shmuel
name: Shavit, Reut
name: Behar, Adi
name: Segoli, Michal
Publisher: name: figshare
Year: 2019
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 1. Appendix A Bacterial communities of different sample types and in the guts of C. palumbus weevils at different developmental stages. Appendix B. Assessment of the representativeness of soil bacterial communities in Negev Desert. Appendix C. Suggested functions of different species of Citrobacter from a wide range of insects. Appendix D: Location of sampling sites. Appendix E. Sampling and sequencing details of all analyzed samples
MOESM1 of Associations between vaping and relapse to smoking: preliminary findings from a longitudinal survey in the UK
Creators: name: Brose, Leonie
name: Bowen, Julia
name: McNeill, Ann
name: Timea Partos
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Additional file 1: Table S1. Attrition rates for all wave 4 ex-smokers. Table S2. Ethnicity, n=374. Table S3. Relapse by respondent characteristic showing all responses individually for variables where response options were combined for the main analysis.
New Insights into Interstellar Object 1I/2017 U1 (`Oumuamua) from SOHO/STEREO Nondetections
Creators: name: Hui, Man-To
name: Knight, Matthew M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Object 1I/2017 U1 (`Oumuamua) is the first interstellar small body ever discovered in the solar system. By the time of discovery, it had already passed perihelion. To investigate the behavior of `Oumuamua around perihelion, we searched for it in Solar and Heliospheric Observatory (SOHO) and Solar TErrestrial RElations Observatory (STEREO) images from early 2017 September (preperihelion), but did not detect it. The nondetection of `Oumuamua by STEREO renders more stringent constraints on its physical properties thanks to the extreme forward-scattering observing geometry. Assuming geometric albedo $p_V = 0.1$, the effective scattering cross-section of any dust coma was $\lesssim \left(2.1 \pm 0.2 \right) \times 10^{4}$ m$^{2}$. Assuming it behaved like a typical solar-system comet this would correspond to a total mass of $\lesssim 20 \pm 2$ kg, and a water production rate of $\lesssim \left(6.1 \pm 0.5 \right) \times 10^{25}$ s$^{-1}$ at heliocentric distance $r_{\rm H} = 0.375$ au. If scaled to post-discovery $r_{\rm H}$, the water production rate would be smaller than any of the previously reported upper limits by at least an order of magnitude. To exhibit the reported nongravitational motion with our default assumptions requires a nucleus bulk density $\lesssim$40 kg m$^{-3}$; higher bulk densities are possible for other assumptions. Alternatively, we show that thermal fracturing could have plausibly removed an inert surface layer between these observations and discovery, thus initiating activity after `Oumuamua left the field of view of STEREO.
description: 10 pages, 3 figures; accepted by AJ
Quantum Cloning of Mixed States in Symmetric Subspace
Creators: name: Fan, Heng
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum cloning machine for arbitrary mixed states in symmetric subspace is proposed. This quantum cloning machine can be used to copy part of the output state of another quantum cloning machine and is useful in quantum computation and quantum information. The shrinking factor of this quantum cloning achieves the well-known upper bound. When the input is identical pure states, two different fidelities of this cloning machine are optimal.
description: Revtex, 4 pages
Sources of Economic Variability in Cattle Feeding
Creators: name: Jones, Rodney
name: Mintert, James
name: Langemeier, Michael
name: Schroeder, Ted
name: Jones, Rodney
name: Mintert, James
name: Langemeier, Michael
name: Schroeder, Ted
Publisher: name: Unknown
Year: 1996
Subjects: Agricultural marketing

description: Previous researchers have identified factors that contribute to variability of profits and feeding cost of gain in cattle feeding. Efforts have been made to identify the relative importance of specific factors in order to assist cattle feeders in managing economic risks. The results of this research suggest that these relationships are not stable over time, and are highly unpredictable. This implies that risk management strategies for cattle feeders may be more difficult to identify and implement than previously thought
Nanoscale imaging of equilibrium quantum Hall edge currents and of the magnetic monopole response in graphene
Creators: name: Uri, Aviram
name: Kim, Youngwook
name: Bagani, Kousik
name: Lewandowski, Cyprian K.
name: Grover, Sameer
name: Auerbach, Nadav
name: Lachman, Ella O.
name: Myasoedov, Yuri
name: Taniguchi, Takashi
name: Watanabe, Kenji
name: Smet, Jurgen
name: Zeldov, Eli
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The recently predicted topological magnetoelectric effect and the response to an electric charge that mimics an induced mirror magnetic monopole are fundamental attributes of topological states of matter with broken time reversal symmetry. Using a SQUID-on-tip, acting simultaneously as a tunable scanning electric charge and as ultrasensitive nanoscale magnetometer, we induce and directly image the microscopic currents generating the magnetic monopole response in a graphene quantum Hall electron system. We find a rich and complex nonlinear behavior governed by coexistence of topological and nontopological equilibrium currents that is not captured by the monopole models. Furthermore, by utilizing a tuning fork that induces nanoscale vibrations of the SQUID-on-tip, we directly image the equilibrium currents of individual quantum Hall edge states for the first time. We reveal that the edge states that are commonly assumed to carry only a chiral downstream current, in fact carry a pair of counterpropagating currents, in which the topological downstream current in the incompressible region is always counterbalanced by heretofore unobserved nontopological upstream current flowing in the adjacent compressible region. The intricate patterns of the counterpropagating equilibrium-state orbital currents provide new insights into the microscopic origins of the topological and nontopological charge and energy flow in quantum Hall systems.
MOESM1 of Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study
Creators: name: Glaser, Rebecca L.
name: York, Anne
name: Dimitrakakis, Constantine
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 1. Statistical Methods and Results
Introduction presentation for the UKRI Net Zero Digital Research Infrastructure project open meeting
Creators: name: Juckes, Martin
name: Townsend, Poppy
name: Bulpett, Jennifer
name: Pascoe, Charlotte
Publisher: name: Zenodo
Year: 2022
Subjects: net zero
computing
digital research infrastructure
data
carbon neutral
zero carbon

description: This presentation was given in December 2021 and January 2022 during the Open Meetings for the UKRI Net Zero Digital Research Infrastructure Project. The purpose of the Open Meetings was to engage the UK research community with the new project, gather ideas, and advertise how people can get involved with the project. A recording from the January meeting can be found here. The project is being led by a team at the Centre for Environmental Data Analysis (CEDA). * UKRI = UK Research and Innovation
General fractional calculus and Prabhakar's theory
Creators: name: Giusti, Andrea
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mathematical Physics (math-ph)
subject: Functional Analysis (math.FA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: General fractional calculus offers an elegant and self-consistent path toward the generalization of fractional calculus to an enhanced class of kernels. Prabhakar's theory can be thought of, to some extent, as an explicit realization of this scheme achieved by merging the Prabhakar (or, three-parameter Mittag-Leffler) function with the general wisdom of the standard (Riemann-Liouville and Caputo) formulation of fractional calculus. Here I discuss some implications that emerge when attempting to frame Prabhakar's theory within the program of general fractional calculus.
description: 10 pages, no figures
Short-Run Captive Supply Relationships with Fed Cattle Transaction Prices
Creators: name: Ward, Clement E.
name: Koontz, Stephen R.
name: Ward, Clement E.
name: Koontz, Stephen R.
Publisher: name: Unknown
Year: 1996
Subjects: Agricultural marketing

description: Questions have been raised about the impacts on spot market prices from meatpackers purchasing fed cattle two or more weeks in advance of slaughter. Three base models were estimated to study: (1) the relationship between use of captive supplies and fed cattle transaction prices; (2) the impact on fed cattle transaction prices from buyers having an inventory of fed cattle procured by captive supply methods from which to deliver cattle for slaughter; and (3) price differences between cash transaction prices and prices for fed cattle purchased under different captive supply methods. There was some evidence that impacts from either delivering cattle from an inventory of captive supplies or having an inventory of captive supply cattle were negative to small. Forward contract prices were found to be significantly lower than cash fed cattle prices.
Baxter Algebras, Stirling Numbers and Partitions
Creators: name: Guo, Li
Publisher: name: arXiv
Year: 2004
Subjects: subject: Commutative Algebra (math.AC)
subject: Combinatorics (math.CO)
subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 16W99,11B73,05A18

description: Recent developments of Baxter algebras have lead to applications to combinatorics, number theory and mathematical physics. We relate Baxter algebras to Stirling numbers of the first kind and the second kind, partitions and multinomial coefficients. This allows us to apply congruences from number theory to obtain congruences in Baxter algebras.
description: 10 pages
Short-term response to alemtuzumab in CD52-positive secondary histiocytic sarcoma in a child: Is it time to consider new targets?
Creators: name: Valera, Elvis Terci
name: Brassesco, María Sol
name: Reis, Maristella Bergamo Francisco Dos
name: Maggioni, Gilberto
name: Guerino-Cunha, Renato Luiz
name: Grecco, Carlos Eduardo
name: Elias, Jorge
name: Kato, Mery
name: Luiz Gonzaga Tone
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Short-term response to alemtuzumab in CD52-positive secondary histiocytic sarcoma in a child: Is it time to consider new targets?
A PROFESSIONAL PERSPECTIVE ON ANAESTHESIA CARE
Creators: name: Razakov, Alisher
name: Rasulov, Olimjon
name: Ahmedov, Y.M.
Publisher: name: Zenodo
Year: 2025

description: Anesthesia care is a comprehensive approach to ensuring the painlessness and safety of the patient during medical procedures. The article describes the main tasks of anesthesia care and considers types of anesthesia. The stages of preparation for anesthetic care are described. The cases when this care is required are listed. The safety and risks of anesthetic care are discussed. Recommendations for further information are given.
Continuum limit of discrete Sommerfeld problems on square lattice
Creators: name: Sharma, Basant Lal
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: A low frequency approximation of the discrete Sommerfeld diffraction problems, involving the scattering of a time harmonic lattice wave incident on square lattice by a discrete Dirichlet or a discrete Neumann half-plane, is investigated. It is established that the exact solution of the discrete model converges to the solution of the continuum model, i.e. the continuous Sommerfeld problem, in certain discrete Sobolev space defined by W. Hackbusch. The proof of convergence has been provided for both types of boundary conditions when the imaginary part of incident wavenumber is positive.
MOESM1 of Factors associated with relevant knowledge of intestinal schistosomiasis and intention to participate in treatment campaigns: a cross sectional survey among school children at Ijinga Island on Lake Victoria, North-Western Tanzania
Creators: name: Parisi, Sandra
name: Mazigo, Humphrey
name: Kreibich, Saskia
name: Puchner, Karl
name: Kasang, Christa
name: Mueller, Andreas
Publisher: name: figshare
Year: 2019
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Ijinga Schistosomiasis control project: School aged Children Questionnaire.
Towards exploring $U_{e3}$
Creators: name: Yasuda, Osamu
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It is emphasized that resolution of the $θ_{23}$ ambiguity is important for determination of $θ_{13}$ if $\sin^22θ_{23}<1$, and resolution of the sgn($Δm^2_{31}$) ambiguity is important for determination of the CP phase $δ$. I discuss the prospects of resolution of the $θ_{23}$ ambiguity etc. in the future long baseline experiment after the JPARC experiment measures the oscillation probabilities $P(ν_μ\toν_e)$ and $P(\barν_μ\to\barν_e)$ at $|Δm^2_{31}|L/4E=π/2$.
description: 8 pages, 5 sets figures, uses ws-procs9x6.cls. Invited talk at 5th Workshop on Neutrino Oscillations and their Origin (NOON2004), Odaiba, Tokyo, Japan, 11-15 Feb 2004
An Economic Analysis of U.S. Broiler Industry: A Structural Bayesian VAR Approach
Creators: name: Karnum, Chandrashekar
name: McIntosh, Christopher
name: Karnum, Chandrashekar
name: McIntosh, Christopher
Publisher: name: Unknown
Year: 1996
Subjects: Agricultural marketing

description: The U.S. broiler industry has seen major structural changes due to higher degrees of vertical integration and industry concentration. These structural changes have influenced the adjustment characteristics of key production variables to external disturbances. We examine these adjustment characteristics to external shocks in a dynamic context. A VAR approach was used to simulate the impulse response functions and forecast error variances. The results show that a positive feed cost shock leads to gradual declines in production and lagged increases in wholesale broiler prices. Shocks to wholesale prices yield a tepid production response. However, a sudden increase in production depresses the wholesale price of broilers. These results imply that feed cost increases pay a major role in the growth of the U.S. broiler industry. Improvements in feed conversion ratio, advances in production technology and adoption of better risk management practices at the national and farm level may help minimize the influence of feed cost.
Integrated Climate Data Center (ICDC) at the Cluster of Excellence at the University of Hamburg
Creators: name: Stockhause, Martina
name: Höck, Heinke
Publisher: name: Geographisches Institut der Universität zu Köln - Kölner Geographische Arbeiten
Year: 2010
Subjects: Earth System Science
Climate Research
Data Portal
Metadata
Data Management

description: At the KlimaCampus (http://www.klimacampus.de), Cluster of Excellence at the University of Hamburg, an Integrated Climate Data Center (ICDC: http://www.icdc.zmaw.de) is established, suitable for data during the scientific project phase as well as storing long-term archive data. ICDC aims to make data out of different internal and external archives easily accessible for the daily work of the KlimaCampus scientists. It extends the existing services by the announcement of data during the scientific project phase, a data portal and collaboration services. Therein, ICDC utilizes the available infrastructure at the WDC Climate by using it for metadata storage and as a long-term archive. The concept of ICDC, its functionality, its implementation status, and future perspectives are presented.
description: Proceedings of the Data Management Workshop, 29-30 October 2009, University of Cologne, Germany, Kölner Geographische Arbeiten, 90, pp. 127-135
Hyperspherical partial wave calculation for double photoionization of the helium atom at 20 eV excess energy
Creators: name: Das, J. N.
name: Chakrabarti, K.
name: Paul, S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Hyperspherical partial wave approach has been applied here in the study of double photoionization of the helium atom for equal energy sharing geometry at 20 eV excess energy. Calculations have been done both in length and velocity gauges and are found to agree with each other, with the CCC results and with experiments and exhibit some advantages of the corresponding three particle wave function over other wave functions in use.
description: 11 pages, 1 figure, submitted to J. Phys B: At. Mol. Opt. Phys; v2 - revised considerably, rewritten using ioplatex class
MOESM4 of Significant association between clinical characteristics and changes in peripheral immuno-phenotype in large vessel vasculitis
Creators: name: Matsumoto, Kotaro
name: Suzuki, Katsuya
name: Yoshimoto, Keiko
name: Noriyasu Seki
name: Tsujimoto, Hideto
name: Chiba, Kenji
name: Takeuchi, Tsutomu
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 4 :Table S1. Antibodies used in FACS analysis. Table S2. Immuno-phenotyping strategy using antibody staining.
DEMAND FOR QUANTITY VERSUS QUALITY IN BEEF, CHICKEN AND FISH CONSUMPTION IN NIGERIA
Creators: name: Ogundari, Kolawole
name: Ogundari, Kolawole
Publisher: name: Unknown
Year: 2012
Subjects: subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Beef
subject: Chicken
subject: Fish
subject: Quantity
subject: Quality
subject: Elasticities
subject: Engel curve
subject: Nigeria

description: This study examines income elasticity of demand for quantity and quality beef, chicken, and fish in Nigeria. The analysis is based on randomly selected 134 households in Ondo state. The empirical results show that income elasticity of demand for beef, chicken, and fish are inelastic. This suggests that these food items are considered necessities among households in the sample. The computed income elasticity of demand for quality was found to be positive for all food items. The implication of this is that demand for quality beef, chicken, and fish increased as income of the household rises. Thus, from policy standpoint, this evidence could be explored to facilitate a better design of food policies aim at improving consumer welfare in Nigeria.
Preparation, characterization and antimicrobial activity evaluation of electrospun PCL nanofiber composites of resveratrol nanocrystals
Creators: name: Alptug Karakucuk
name: Tort, Serdar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Hematology

description: The objective of this study was to develop resveratrol nanocrystals to solve low water solubility issues of resveratrol and adsorb them to the polycaprolactone nanofibers. Nanocrystals were prepared by microfluidization. Particle size, polydispersity index and zeta potential values were evaluated as dependent variables. Polycaprolactone (PCL) nanofibers were prepared via electrospinning method and the flow rate, electrical voltage and tip-to-collector distance were set to 3 mL/h, 13 kV and 15 cm, respectively. Optimum resveratrol nanocrystals were lyophilized and re-suspended in water and physically adsorbed to PCL nanofibers with two different concentrations (0.2 and 1 mg/cm2). Bioadhesion, wettability, solubility, drug loading and antimicrobial activity against Propionibacterium acnes studies were carried out. Final nanocrystals showed 800 nm of particle size, 0.4 of polydispersity index, and −8 mV of zeta potential. Nanocrystals successfully adsorbed to PCL nanofibers proven on SEM images with adsorption efficiencies >70%. Adsorption of resveratrol nanocrystals decreased the contact angle of PCL from 128° to 50°. The solubility of resveratrol nanocrystals enhanced ∼5-fold in comparison with coarse powder. Effective antimicrobial activity against P. acnes was observed. It is concluded that nanocrystal loading on nanofibers brings advantage into preparing easy to use dermal patches for acne treatment or skin disorders.
Molecular rectifying diodes from self-assembly on silicon
Creators: name: Lenfant, Stephane
name: Krzeminski, Christophe
name: Delerue, Christophe
name: Allan, Guy
name: Vuillaume, Dominique
Publisher: name: arXiv
Year: 2003
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We demonstrate a molecular rectifying junction made from a sequential self-assembly on silicon. The device structure consists of only one conjugated (p) group and an alkyl spacer chain. We obtain rectification ratios up to 37 and threshold voltages for rectification between -0.3V and -0.9V. We show that rectification occurs from resonance through the highest occupied molecular orbital of the p-group in good agreement with our calculations and internal photoemission spectroscopy. This approach allows us to fabricate molecular rectifying diodes compatible with silicon nanotechnologies for future hybrid circuitries.
A surfactant-stripped cabazitaxel micelle formulation optimized with accelerated storage stability
Creators: name: Boyang Sun
name: Jing, Huang
name: Mabrouk, Moustafa T.
name: Yumiao Zhang
name: Honglin Jin
name: Lovell, Jonathan F.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Pluronic (Poloxomer) micelles can solubilize cabazitaxel (CTX), a second-generation taxane, and then be subjected to low-temperature “surfactant-stripping” to selectively remove loose and free surfactant, thereby increasing the drug-to-surfactant ratio. We previously found that the addition of certain other co-loaded hydrophobic cargo to the micelles can result in stabilized, surfactant-stripped cabazitaxel (sss-CTX) micelles, which resist drug aggregation in aqueous storage, a common challenge for taxanes. Here, we show that elevated temperatures can accelerate the aggregation of sss-CTX micelles, thereby enabling rapid optimization of formulations with respect to the type and ratio of co-loader used for stabilization. A sss-CTX micelle formulation was developed using mifepristone as the co-loader, at a 60% mass ratio to the CTX. Drug release, hemolysis and complement activation were investigated in vitro. Microtubule stabilization and in vitro cytotoxicity were similar for sss-CTX and a conventional Tween-80 micelle formulation. In vivo pharmacokinetics also revealed similar blood circulation of the two formulations. In subcutaneous Lewis lung carcinoma tumors, as well as in an aggressive mouse model of malignant pleural effusion, sss-CTX showed a similar therapeutic effect as the Tween-80 based formulation. Altogether, these data show that sss-CTX can achieve similar efficacy as conventional Tween-80 formulations, albeit with substantially higher drug-to-surfactant ratio and with capability of extended aqueous storage.
Additional file 1 of Sepsis-related hospital admissions and ambient air pollution: a time series analysis in 6 Chinese cities
Creators: name: Wang, Yu
name: Liu, Zhen
name: Yang, Lian
name: Zhou, Jiushun
name: Li, Jia
name: Liao, Hai Lun
name: Tian, Xing Jun
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biotechnology
Computational Biology

description: Additional file1 Table S1. Detailed ICD codes for the identification of sepsis. Table S2. Limit of pollutant concentration and Individual air quality index. Table S3. The city-specific percentage increase (estimates and 95% CI) in daily hospital admissions of sepsis associated with 10-μg/m3 increase in NO2 and O3 concentrations at lag day with the highest estimates of basic models for total populations. Table S4. Percentage increase (estimates and 95% CI) in daily hospital admissions of sepsis associated sepsis of 10-μg/m3 increase in PM2.5, PM10 and SO2 concentrations, and 1 mg/m3 increase in CO, stratified by age and sex.
Prediction of saxagliptin stability using a new approach based on Partial Least Squares and Design of Experiments
Creators: name: Jordan, Nika
name: Zakrajšek, Jure
name: Bohanec, Simona
name: Roškar, Robert
name: Grabnar, Iztok
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: The objective of this study was to assess the possibility of applying Partial Least Squares (PLS) statistics with the use of experimental design approach towards stability evaluation of the Saxagliptin drug product. The influences of temperature, time, dose, packaging, batch, and oxygen protection were analyzed for identification of critical factors responsible for degradation of saxagliptin and prediction of impurity levels at various storage conditions. Predicted levels of the impurity DP-2 were lower for at least 0.2 % when the drug product was protected from oxygen after its manufacture. Additionally, the PLS model revealed that the lower strength is at least twice less stable concerning impurity DP-1. Based on this analysis shelf life for Zone II was proposed at 24 months with high reliability. Comparison of the PLS model estimates with the measured stability data at shelf life revealed good predictive ability of the developed model. Moreover, PLS predictions of DP-1 and Total impurities were more accurate than those obtained with a standard linear least squares regression, while DP-2 predictions were at least as accurate. We can thus propose a more extensive use of this approach for stability evaluation of pharmaceuticals.
Testing Chiral Dynamics in Pionic Atoms
Creators: name: Friedman, E.
name: Gal, A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The energy dependence of chirally expanded pi N isoscalar and isovector amplitudes b_0(E) and b_1(E) respectively, for zero-momentum off shell pions near threshold, is used to impose the minimal substitution requirement E -> E - V_c on the properly constructed pion optical potential within a large-scale fit to 100 pionic-atom data across the periodic table which also include the recently established `deeply bound' pionic atoms of Pb and Sn. This fit cannot be reconciled with the well known free-space values of the pi N threshold amplitudes. In contrast, introducing the empirically known energy dependence for on-shell pions leads to a better fit and to satisfactory values for the pi N threshold amplitudes. The difference between these two approaches is briefly discussed.
description: 10 pages, 3 figures, submitted to PLB. Discussion section rewritten, omitting an erroneous equation. Results and conclusions unchanged Accepted by PLB
BACKGROUND TO THE PRODUCTION AND USE OF BIOETHANOL AS FUEL IN HUNGARY
Creators: name: Reczey, Gabor
name: Bai, Attila
name: Reczey, Gabor
name: Bai, Attila
Publisher: name: Unknown
Year: 2006
Subjects: subject: Crop Production/Industries
subject: Production Economics
subject: Resource /Energy Economics and Policy
subject: biofuels
subject: tax
subject: corn as raw material
subject: ethanol factory

description: In Hungary difficulties in the utilisation of bio-fuels are mainly caused by problems of economy and not by technical problems. Currently, the key factor in development – according to the authors of this article – would be a new version of the relevant legal provisions, which would allow MOL (the Hungarian Gas and Oil Company) and other big consumers (like transport companies BKV, DKV), to mix bio-fuels in a higher proportion than 5% with 0% excise tax. Environmental, technical, and rural development aspects support such a change in the law. Moreover the 0% excise tax on bio-fuels is used in many other countries as well without significant deficit in the national finances. This would have a positive effect on the production and utilisation of bio-fuels, even in the present agricultural situation. Moreover, this would provide a sound economic basis for future developments and a perspective for other bio-fuel producers.
IMAGE OR MIRROR IMAGE? SOME THOUGHTS ON SUSTAINABILITY
Creators: name: Szlavik, Janos
name: Csete, Maria
name: Szlavik, Janos
name: Csete, Maria
Publisher: name: Unknown
Year: 2006
Subjects: subject: Agricultural and Food Policy
subject: Resource /Energy Economics and Policy
subject: sustainable development
subject: traditional macroeconomic indicators
subject: externalities
subject: public good versus public bad
subject: economic growth or development

description: The shortcomings and biases of traditional macroeconomic indicators are even more obvious if we analyse them from the point of view of sustainability. There are different goods and services behind monetary units measuring the economy. Some goods serve life while others can lead to death. Indicators measuring economic growth, e.g. GDP, completely conceal this difference. The growth of GDP is slowly becoming the only goal and in many cases this is not compatible with the idea of sustainability. Mainstream economics still assumes that all goods produced serve welfare. We have to consider the external effects of our activities, realising that negative externalities result in public bad and not public good, and that hidden positive externalities may result in social losses. In the case of negative externalities the growth of positive GDP is misleading, because society has to pay a high price for this positive image (with degradation of the natural and built environment, health problems, loss of biodiversity etc.). The main difference between traditional, growth oriented economic strategies and sustainability is how economic development is seen. Thus, in the case of sustainability, the aim is development instead of simple growth, quality instead of quantity, and the economy serves as a tool. In this context, how coherent and consistent various goals, programmes and strategies are in practice was also investigated. From the point of view of realising sustainable development, we consider the regional level important for several reasons, therefore, in the second part of our study we analyse the relationship of sustainability and convergence.
Exploration Without Global Consistency Using Local Volume Consolidation
Creators: name: Cieslewski, Titus
name: Ziegler, Andreas
name: Scaramuzza, Davide
Publisher: name: arXiv
Year: 2019
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: In exploration, the goal is to build a map of an unknown environment. Most state-of-the-art approaches use map representations that require drift-free state estimates to function properly. Real-world state estimators, however, exhibit drift. In this paper, we present a 2D map representation for exploration that is robust to drift. Rather than a global map, it uses local metric volumes connected by relative pose estimates. This pose-graph does not need to be globally consistent. Overlaps between the volumes are resolved locally, rather than on the faulty estimate of space. We demonstrate our representation with a frontier-based exploration approach, evaluate it under different conditions and compare it with a commonly-used grid-based representation. We show that, at the cost of longer exploration time, using the proposed representation allows full coverage of space even for very large drift in the state estimate, contrary to the grid-based representation. The system is validated in a real world experiment and we discuss its extension to 3D.
description: 16 pages with large margins, accepted for publication at the International Symposium on Robotics Research (ISRR), Hanoi, 2019
MOESM1 of Antiplasmodial profile of selected compounds from Malaria Box: in vitro evaluation, speed of action and drug combination studies
Creators: name: Souza, Guilherme
name: Bueno, Renata
name: Souza, Juliana
name: Zanini, Camila
name: Fábio Cruz
name: Glaucius Oliva
name: Guido, Rafael
name: Aguiar, Anna
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Fig. S1. Fragments of the dendrogram originated from the hierarchical clustering of 400 compounds from the Malaria Box, artesunate and atovaquone. Clusters 2, 16, 20, 23 and 25 are represented with the 2D structures from which they originated. Fig. S2. Fragments of the dendrogram originated from the hierarchical clustering of 400 compounds from Malaria Box, artesunate and atovaquone. Clusters 26, 27, 29, 32, 35 and 36 are represented with the 2D structures from which they originated. Fig. S3. Concentration-response curves of the selected compounds from the Malaria Box against P. falciparum (3D7). Curves in black and red refer to, respectively, the first and second experiment performed for the evaluation of the IC50 values. Fig. S4. Evaluated versus reported pIC50 values
Additional file 2 of Haem relieves hyperoxia-mediated inhibition of HMEC-1 cell proliferation, migration and angiogenesis by inhibiting BACH1 expression
Creators: name: Jian, Lan
name: Mei, Yang
name: Xing, Chen
name: Rongdi, Yuan
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: Additional file 2. The STR test result of HMEC-1 cells.
Perturbations in the Einstein theory of gravity: Conserved currents
Creators: name: Petrov, A. N.
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: General relativity in the form where gravitational perturbations together with other physical fields propagate on an auxiliary background is considered. With using the Katz-Bi{č}ák-Lynden-Bell technique new conserved currents, divergences of antisymmetric tensor densities(superpotentials), in an arbitrary curved spacetime are constructed.
description: LATEX, 8 pages
Myeloid cell leukemia-1 as a candidate prognostic biomarker in cancers: a systematic review and meta-analysis
Creators: name: Wang, Jianrong
name: He, Yu
name: Yang, Chao
name: Luo, Qiurui
name: Wang, Bingchi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology

description: Studies have shown that myeloma cell leukemia-1 (MCL-1) is associated with the prognosis of patients with cancer. To further validate the prognostic value of MCL-1 in cancer, a meta-analysis was conducted. Six databases were searched using Boolean logic search formulas. Data were extracted from the included literature, and pooled odds ratio, hazard ratio, and 95% confidence interval were calculated to determine the relationship between MCL-1 levels and clinicopathological characteristics and prognosis of patients with cancer. When heterogeneity was found to be significant, a random effects model was used, otherwise, a fixed effects model was used. Twelve articles were included in this meta-analysis, totaling 2208 patients with cancer across 14 studies. A high MCL-1 expression level was associated with patients with high T stage, M stage, and TNM stage in some cancers. Additionally, high MCL-1 expression was likely to be observed in patients with poorly differentiated digestive system tumors and patients with lung adenocarcinoma. Notably, a higher expression of MCL-1 was found to be associated with shorter overall survival in patients with hematological tumors, digestive system tumors, and lung cancer. MCL-1 may be a prognostic biomarker in patients with some types of cancer.
THE INTERACTIONS OF THE NATURAL ENVIRONMENT AND SUSTAINABLE AGRICULTURAL PRODUCTION
Creators: name: Fabian, Gyula
name: Marselek, Sandor
name: Abay-Hamar, Eniko
name: Fabian, Gyula
name: Marselek, Sandor
name: Abay-Hamar, Eniko
Publisher: name: Unknown
Year: 2006
Subjects: subject: Agricultural and Food Policy
subject: Resource /Energy Economics and Policy
subject: environmental management
subject: external effects
subject: sustainable development
subject: agricultural production
subject: ecological economics

description: The accelerating consumption of natural resources has caused significant economic growth and improved financial conditions in industrial countries, but destroys the forests, soil, air, water and the biological diversity of the Earth. By ecologically overloading our planet, economic development is becoming self-destructive. Many scientists believe that this tendency can even threaten the existence of mankind. At international levels, the condition of Hungary’s natural environment is considered average, and it is gradually improving. However, the environmental condition of the Earth is continually deteriorating and this process is accelerating. The main factors in environment pollution are industrial production, transportation and energy production, but littering and sewage are also significant. The special pollution of the different sectors of the agricultural economy, particularly industrial output, cannot be neglected either. There are complex interactions between the natural environment and agricultural production. The damaging effects of agricultural industries are mainly due to overusing fertilisers and pesticides. Animal husbandry pollutes the environment with liquid manure and chemicals, while power machines cause air pollution, soil compression, and oil and fuel pollution, also damaging the environment. Ecological and integrated farming is less harmful to the environment, so the new agricultural model can lead us to sustainable agricultural development. Sustainable development is indispensable to preserving the natural environment. It would make it possible to use and, at the same time, preserve natural resources on global, regional (national) and local levels. The aim of subsidies should also be the creation of a ‘liveable countryside’. In Hungary, the National Environmental Protection Programme was introduced in order to encourage sustainable development and reduce environment pollution. One of its sub-programmes, the National Agricultural Environmental Protection Programme helps support environmentally friendly farming.
D7.4 DATA MARKETPLACE: DESIGN AND OPEN SPECIFICATION
Creators: name: Mavrogiorgou, Argyro
name: Kiourtis, Thanos
name: Karagiannis, Fotis
name: Willems, Marieke
Publisher: name: Zenodo
Year: 2021
Subjects: data
data marketplace

description: This deliverable (entitled “Data Marketplace: Design and Open Specification”) describes the initial design and specifications of the PolicyCLOUD Data Marketplace. The Data Marketplace will be a unified web- based platform consisting of two (2) core services, its front-end and back-end, offering its users various ready-to-use solutions. More specifically, it will provide to the wider research and innovation community various assets (i.e. objects/solutions) in different domains. As a Marketplace, the current design provides information on how several users (and contributors) can interact with the Marketplace in order to ingest and retrieve the respective assets, through potential user journeys that are analyzed. Moreover, the deliverable introduces the different types of offered assets, since the Data Marketplace will go beyond policies and tools and will store and offer additional elements, including rich descriptions of the offered assets, algorithms, validation datasets, and in general different outcomes of the project.
 To support the aforementioned functionalities, the PolicyCLOUD Data Marketplace specifications exemplify the respective layers of the Marketplace, the functionalities supported by each layer, the interaction points with different stakeholders as well as the technical details that will drive the implementation of the Marketplace. Finally, it reviews the current state of the art in order to identify the baseline technologies and approaches for the realization of the implemented Marketplace.
Additional file 1 of Haem relieves hyperoxia-mediated inhibition of HMEC-1 cell proliferation, migration and angiogenesis by inhibiting BACH1 expression
Creators: name: Jian, Lan
name: Mei, Yang
name: Xing, Chen
name: Rongdi, Yuan
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: Additional file 1. The certificate of HMEC-1 cells from ATCC.