cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
"Les gens de cette place": Oblates and the Evolving Concept of Métis at Île-à-Crosse, 1845-1898
Creators: name: Foran, Timothy P.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Oblates of Mary Immaculate
Catholic missions
Western Canada
Northern Saskatchewan
Metis
Categories of indigeneity

description: This dissertation examines the construction and evolution of categories of indigeneity within the context of the Oblate (Roman Catholic) apostolate at Île-à-Crosse in present-day north-western Saskatchewan between 1845 and 1898. While focusing on one central mission station, this study illuminates broad historical processes that informed Oblate perceptions and impelled their evolution over a fifty-three-year period. In particular, this study illuminates processes that shaped Oblate concepts of sauvage and métis. It does this through a qualitative analysis of missionary correspondence, mission records and published reports. In the process, this dissertation challenges the orthodox notion that Oblate commentators simply discovered and described a singular, empirically existing and readily identifiable Métis population. Rather, this dissertation contends that Oblates played an important role in the conceptual production of les métis.
The Impact of Foreign Language Anxiety on Speaking Abilities of Moroccan EFL Universities Students
Creators: name: Atras Journal
Publisher: name: Zenodo
Year: 2022

description: It is prima facie valid that joining English studies at the universities has become very popular among Moroccan students. The reason behind this fact is the vital status that English has for all kinds of personal and professional aspects. However, most students in EFL Moroccan university classes seem to be reluctant to speak and interact orally in English due to the feeling of foreign language anxiety. Therefore, the purpose of this study was to find out the impact of anxiety on speaking abilities of Moroccan university students. It pinpointed the sources of foreign language anxiety and hopefully,it would contribute to the field of English language teaching in Morocco by suggesting strategies that can be used by students and teachers to overcome a widely spread phenomenon such as speaking anxiety. To do this, mixed method was adopted through two instruments. TheForeign Language Classroom Anxiety Scale questionnaire for quantitative data, which was given to 80 participants of EFL university students, and teachers’ interviews for qualitative data that were conducted with 8 experienced EFL teachers. The resultsobtained showed that FLA has a negative impact on speaking abilities of Moroccan university students. Furthermore, teachers admitted that students who suffer from anxiety tend to have low speaking skills. Therefore, it was recommended that students should build a strong personality, confidence and enhance their language skills. Also, teachers should be supportive and creative to help students overcome foreign language anxiety.Keywords: foreign language anxiety, speaking abilities, strategies, sources
From the Temple to the Witch’s Coven: Journeying West with Kali Ma, Fierce Goddess of Transformation. A Study of Contemporary Kali Worship in North America: Syncretism, Sacred Relationships, and the Gendered Divine
Creators: name: Kuchuk, Nika
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Kali (Hindu goddess)
Hinduism
Contemporary religion (North America)
Feminist spirituality
Goddess religion
syncretism
gendered divine
ritual
ethnography
Religion in the West
Shaktism
Neopaganism
Witchcraft

description: This thesis explores the cult and mythos of the goddess Kali both in her Eastern and Western contexts, comparing and contrasting them in order to gain a better understanding of the Western appropriations of Kali within feminist goddess spirituality. Utilizing a variety of methods, including ethnographic research conducted at Kali temples in California, this research is aimed at providing an entry into the lived contemporary tradition of the Western Kali within goddess spirituality circles, focusing on embodied experience, devotion, ritual, and syncretic practices. Kali, a fierce Indian goddess, is often seen in the Hindu context as a central manifestation of the all encompassing Mother Goddess (Mahadevi, Devi, Shakti, etc), and therefore is a particularly engaging example of contemporary Western appropriation of religious and cultural symbols and narratives. This thesis contributes to understanding Kali in her new North American domain, as well as serving as a case study of the shifting religious landscape in the West.
The contribution of qualitative research within the PRECISE study in sub-Saharan Africa
Creators: name: Daniele, Marina A S
name: Martinez-Alvarez, Melisa
name: Etyang, Angela K
name: Vidler, Marianne
name: Salisbury, Tatiana
name: Makanga, Prestige T
name: Musitia, Peris
name: Flint-O’Kane, Meriel
name: Brown, Tanya W
name: Diallo, Brahima A
name: Boene, Helena
name: Stones, William
name: Von Dadelszen, Peter
name: Magee, Laura A
name: Sandall, Jane
Publisher: name: BioMed Central
Year: 2020

description: The PRECISE Network is a cohort study established to investigate hypertension, fetal growth restriction and stillbirth (described as “placental disorders”) in Kenya, Mozambique and The Gambia. Several pregnancy or birth cohorts have been set up in low- and middle-income countries, focussed on maternal and child health. Qualitative research methods are sometimes used alongside quantitative data collection from these cohorts. Researchers affiliated with PRECISE are also planning to use qualitative methods, from the perspective of multiple subject areas. This paper provides an overview of the different ways in which qualitative research methods can contribute to achieving PRECISE’s objectives, and discusses the combination of qualitative methods with quantitative cohort studies more generally. We present planned qualitative work in six subject areas (health systems, health geography, mental health, community engagement, the implementation of the TraCer tool, and respectful maternity care). Based on these plans, with reference to other cohort studies on maternal and child health, and in the context of the methodological literature on mixed methods approaches, we find that qualitative work may have several different functions in relation to cohort studies, including informing the quantitative data collection or interpretation. Researchers may also conduct qualitative work in pursuit of a complementary research agenda. The degree to which integration between qualitative and quantitative methods will be sought and achieved within PRECISE remains to be seen. Overall, we conclude that the synergies resulting from the combination of cohort studies with qualitative research are an asset to the field of maternal and child health.
Additional file 1 of The first research agenda for the chiropractic profession in Europe
Creators: name: Rubinstein, Sidney M
name: Bolton, Jenni
name: Webb, Alexandra L
name: Hartvigsen, Jan
Publisher: name: figshare
Year: 2020
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1: Appendix 1. Open-ended data collection tool. Appendix 2. Questionnaire at phase 2, Round 1. Appendix 3. Questionnaire at phase 2, Round 2. Appendix 4. Comments from the participants at phase 2, Rounds 1 and 2. Appendix 5. Questionnaire at phase 2, Round 3. (PDF 518 KB)
A New Chronology of the Construction and Restoration of the Medici Guardaroba in the Palazzo Vecchio, Florence
Creators: name: Rosen, Mark
Publisher: name: Mitteilungen des Kunsthistorischen Institutes in Florenz
Year: 2018

description: -
description: Mitteilungen des Kunsthistorischen Institutes in Florenz, Bd. 53, Nr. 2./3. (2009): Mitteilungen des Kunsthistorischen Institutes in Florenz
title: Checklist System for Safety Reports
title: Checklist system for Safety Reports
titleType: AlternativeTitle
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: subject: Sicherheitsstudie
subject: Industrie
subject: Anlagenbetrieb
subject: Leitfaden
subject: Seveso
subject: UNECE
subject: safety report
subject: industrial accident
subject: industrial accidents
subject: safety management
subject: checklist
subject: guideline
subject: Chemikalien
subject: Chemicals

description: Based on the UNECE Convention on the Transboundary Effects of Industrial Accidents and EU Directive 96/82/EC (SEVESO II), this unified guideline system provides important definitions, valuation systems and background information for drawing up and reviewing safety reports. Quelle: Bericht
description: Based on the ⁠UNECE⁠ Convention on the Transboundary Effects of Industrial Accidents and EU Directive 96/82/EC (SEVESO II), this unified guideline system provides important definitions, valuation systems and background information for drawing up and reviewing safety reports.
How sea-level and climate change affect island people: Examples from Yadua Island, Fiji
Creators: name: Martin, Pierick C M
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2018
Subjects: climate change
small island developing states
sea-level rise
Fiji
environmental risk
settlement pattern
oral traditions

description: Climate and sea-level change have been impacting coastal communities in the Pacific Basin for millennia. In many tropical Pacific Islands, these changes have been linked to settlement and farmland relocations, both with rising and falling sea level. This thesis focuses on these effects and examines how the inhabitants of Yadua Island (Fiji) have responded to them following the AD 1300 Event and in the last decade. Between AD 1250 and AD 1350, a period of rapid cooling resulted in sea-level fall and a comprehensive decline in food availability that led to conflicts between tribes in most of the Pacific Basin. In order to better protect themselves, most coastal settlements were abandoned in favour of fortifiable locations, typically on hilltops or in caves. These settlements are called hillforts (koronivalu in iTaukei). The study represents the first investigation of fortifications on Yadua Island, and one of a few in western Vanua Levu, or small Fijian islands. Through semi-structured interviews, two hillforts (Koromakawa and Uluinakoro), and two lookout posts (Nacelau and Uluikota) were located, measured and georeferenced. All sites presented stonewalls, but shellfish and potsherds were only scattered throughout the hillfort sites. Two pits were dug at Uluinakoro, and one at Koromakawa; excavated potsherds and shellfish samples were kept for subsequent analyses. Four shellfish samples (Gafrarium pectinatum, and Anadara antiquata) were sent out to Waikoto University for radiocarbon dating. The results showed an approximate age of 300 to 0 YBP (AD 1700 to now) but considering the depth of the pit (170 cm), they are likely from the older end of the scale. The diagnostic pottery pieces were dated from the Vuda Phase, 700 to 500 YBP (AD 1300 to 1500). Ages around AD 1400 would make them coeval with hillforts elsewhere in Fiji and other tropical Pacific Island groups.
Developing Microfluidic Volume Sensors for Cell Sorting and Cell Growth Monitoring
Creators: name: Riordon, Jason A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Microfluidic
Volume sensing
Coulter principle
PDMS
Soft Lithography
Photolithography
Cell sorting
Cell growth
Hydrodynamic
Electric field
Lab-on-chip

description: Microfluidics has seen an explosion in growth in the past few years, providing researchers with new and exciting lab-on-chip platforms with which to perform a wide variety of biological and biochemical experiments. In this work, a volume quantification tool is developed, demonstrating the ability to measure the volume of individual cells at high resolution and while enabling microfluidic sample manipulations. Care is taken to maximise measurement sensitivity, range and accuracy, though novel use of buoyancy and dynamically tunable microchannels. This first demonstration of a microfluidic tunable volume sensor meant volume sensing over a much wider range, enabling the detection of ̴ 1 µm3 E.coli that would otherwise go undetected. Software was written that enables pressure-driven flow control on the scale of individual cells, which is used to great success in (a) sorting cells based on size measurement and (b) monitoring the growth of cells. While there are a number of macroscopic techniques capable of sorting cells, microscopic lab-on-chip equivalents have only recently started to emerge. In this work, a label-free, volume sensor operating at high resolution is used in conjunction with pressure-driven flow control to actively extract particle/cell subpopulations. Next, a microfluidic growth monitoring device is demonstrated, whereby a cell is flowed back and forth through a volume sensor. The integration of sieve valves allows cell media to be quickly exchanged. The combination of dynamic trapping and rapid media exchange is an important technological contribution to the field, one that opens the door to studies focusing on cell volumetric response to drugs and environmental stimuli. This technology was designed and fabricated in-house using soft lithography techniques readily available in most biotechnology labs. The main thesis body contains four scientific articles that detail this work (Chapters 2-5), all published in peer-reviewed scientific journals. These are preceded by an introductory chapter which provides an overview to the theory underlying this work, in particular the non-intuitive physics at the microscale and the Coulter principle.
title: Mitteilungen des Kunsthistorischen Institutes in Florenz, Bd. 53 Nr. 2/3 (2009): Mitteilungen des Kunsthistorischen Institutes in Florenz
title: Mitteilungen des Kunsthistorischen Institutes in Florenz
titleType: AlternativeTitle
Creators: name: Mitteilungen Des Kunsthistorischen Institutes In Florenz
Publisher: name: Mitteilungen des Kunsthistorischen Institutes in Florenz
Year: 2018

description: Band LIII (2009), Heft 2/3
description: Neue Dokumente zur Vespucci-Kapelle in Ognissanti und zur Familie Domenico Ghirlandaios...364-374
Inter Duos Pontes. Das Adler-Schlangen-Kapitell in der Krypta von San Bartolomeo All'Isola in Rom...355-363
A New Chronology of the Construction and Restoration of the Medici Guardaroba in the Palazzo Vecchio, Florence...285-308
Michelangelo begegnet Dürer: Zu Entwürfen für zwei Schächer und einen Hl. Sebastian...251-284
Das Grabmal für Kardinal Adam Easton in Santa Cecilia in Trastevere und seine Bildhauer: Giovanni D'Ambrogio und Lorenzo Di Giovanni aus Florenz...197-216
Molecular detection of tick-borne pathogens in caracals (Caracal caracal) living in human-modified landscapes of South Africa
Creators: name: Viljoen, Storme
name: O’Riain, M. J
name: Penzhorn, Barend L
name: Drouilly, Marine
name: Serieys, Laurel E K
name: Cristescu, Bogdan
name: Teichman, Kristine J
name: Bishop, Jacqueline M
Publisher: name: BioMed Central
Year: 2020

description: Background: Wild carnivores living alongside humans and domestic animals are vulnerable to changes in the infectious disease dynamics in their populations. The aims of this study were to determine the prevalence and diversity of selected tick-borne pathogens (TBPs) of veterinary and/or zoonotic concern in wild populations of caracals (Caracal caracal) occurring in human-modified landscapes in South Africa. Using molecular techniques, we screened 57 caracal blood samples for infection by rickettsial bacteria and piroplasms in three regions of South Africa: rangeland in the Central Karoo (n = 27) and Namaqualand (n = 14) as well as the urban edge of the Cape Peninsula (n = 16) of South Africa. To characterise pathogen identity, we sequenced the 18S rRNA and 16S rRNA genes from positive samples and analysed sequences within a phylogenetic framework. We also examine the diversity of potential tick vectors. Results: All individuals tested were infected with at least one tick-borne pathogen. Pathogens included Hepatozoon felis, Babesia felis, Babesia leo and a potentially novel Babesia species. An Anaplasma species previously described in South African domestic dogs was also found in 88% of urban edge caracals. Higher rates of co-infection characterised urban edge caracals (81% vs 15% and 0% in the two rangeland populations), as well as a greater incidence of mixed infections. Host attached tick species include Haemaphysalis elliptica, an important pathogen vector among carnivore hosts. Conclusions: This study confirms the occurrence of previously undocumented tick-borne pathogens infecting free-ranging caracals in human-modified landscapes. We identify clear differences in the pathogen profiles among our study populations and discuss the likely health costs to caracals living adjacent to urban areas.
Integration of PDMS membranes into thermoplastic microfluidic packages
Creators: name: Miller, Paul
Publisher: name: Swinburne
Year: 2024

description: This project proposes a novel process to integrate a polydimethylsiloxane (PDMS) membrane into a polycarbonate (PC) microfluidic device. A novel composite material was manufactured by adhesively laminating UV/ozone pretreated PDMS to polycarbonate using Loctite 3105 UV curable adhesive. Hot embossing of this composite produced a microstructured substrate of PC with an adhesively bonded PDMS layer at the surface. This PDMS surface was then exposed to an oxidative media such as oxygen plasma or UV radiation to produce a highly activated PDMS surface that can adhere to itself upon contact. The use of a novel system of PC bonded to PDMS using a UV curable adhesive resulted in adhesion of sufficient strength and durability to withstand the hot embossing process. Optimizing the UV curing parameters maximized joint strength for PC to PDMS bonds. The surface chemistry of the delaminated PDMS was analyzed and used to determine the dependence of adhesive failure mode on UV/ozone treatment parameters. The research conducted proves that an adhesively laminated composite of PDMS and PC can be embossed in a reproducible way with both semi-circular and rectangular tools. The dimensions of the embossed channels can also be modeled in terms of both the embossing parameters and the UV exposure parameters. In summary, this technique can be used to fabricate microfluidic structures in a controlled fashion, and when combined with oxidative exposure of PDMS surfaces, offers an effective way to integrate PDMS membranes into thermoplastic microfluidic devices.
Supplementary document for Deep-ROCS: From speckle patterns to superior-resolved images by deep learning in Rotating Coherent Scattering Microscopy - 5296636.pdf
Creators: name: Shechtman, Yoav
name: Saguy, Alon
name: Junger, Felix
name: Peleg, Aviv
name: Ferdman, Boris
name: Nehme, Elias
name: Rohrbach, Alexander
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Additional information on simulations, resolution quantification, and experimental parameters
Additional file 2 of The first research agenda for the chiropractic profession in Europe
Creators: name: Rubinstein, Sidney M
name: Bolton, Jenni
name: Webb, Alexandra L
name: Hartvigsen, Jan
Publisher: name: figshare
Year: 2020
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Authors’ original file for figure 1
Supplementary document for Deep-ROCS: From speckle patterns to superior-resolved images by deep learning in Rotating Coherent Scattering Microscopy - 5296636.pdf
Creators: name: Shechtman, Yoav
name: Saguy, Alon
name: Junger, Felix
name: Peleg, Aviv
name: Ferdman, Boris
name: Nehme, Elias
name: Rohrbach, Alexander
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Additional information on simulations, resolution quantification, and experimental parameters
Three-and four-derivative Hermite-Birkhoff-Obrechkoff solvers for stiff ODE
Creators: name: Albishi, Njwd
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: general linear method for stiff ODE's
Hermite-Birkhoff-Obrechkoff method
maximum end error
number of function evaluations
CPU time
comparing stiff ODE solvers.

description: Three- and four-derivative k-step Hermite-Birkhoff-Obrechkoff (HBO) methods are constructed for solving stiff systems of first-order differential equations of the form y'= f(t,y), y(t0) = y0. These methods use higher derivatives of the solution y as in Obrechkoff methods. We compute their regions of absolute stability and show the three- and four-derivative HBO are A( 𝜶)-stable with 𝜶 > 71 ° and 𝜶 > 78 ° respectively. We conduct numerical tests and show that our new methods are more efficient than several existing well-known methods.
Stakeholder influence strategies on environmental reporting: exploring the Malaysian context
Creators: name: Elijido-Ten, Evangeline
name: Kloot, Louise
name: Clarkson, Peter
Publisher: name: Swinburne
Year: 2024

description: This research extends the application of stakeholder theory in the environmental reporting area by using Frooman’s (1999) typology of resource relationships and influence strategies to understand how different stakeholder groups go about seeking what they want from the management. This study is organised into two phases. The first phase explores how Frooman’s model can be used in the Malaysian context. Phase 2 adopts an experimental approach using hypothetical vignettes. The findings indicate that although the model is useful to predict the influence strategies taken by each stakeholder group, its effectiveness is tempered by the level of significance placed on the environmental event. The results presented lead to the conclusion that voluntary environmental disclosures are used by corporate entities to manage their possibly competing stakeholder demands. This is in accordance with the basic premise of stakeholder theory.
« À quoi sert au Canadien-Français de gagner l'univers canadien s'il perd son âme de francophone? » Représentations identitaires et mémorielles dans la presse franco-ontarienne après la “rupture” du Canada français (1969-1986)
Creators: name: Miville, Serge
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Nationalisme
Canada français
Ontario français
Hebdomadaires
ACFO
Nationalism
Nationalitaire
presse franco-ontarienne
“rupture” du Canada français (1969-1986)
communautés francophones
revendications franco-ontariennes
French-Canadian identity
"Rupture" of French Canada ( 1969-1986)
Franco-Ontarian newspapers
Journaux franco-ontariens
Identité franco-ontarienne

description: Cette étude de la presse en Ontario français cherche à revenir sur le débat quant à rupture du Canada français et sur l’immense fragmentation identitaire qui se serait opérée dans les communautés francophones du pays en analysant les prises de position de journaux régionaux. La thèse relève d’importants vestiges du Canada français dans la mise en sens par les journaux des revendications franco-ontariennes, notamment en ce qui a trait à la question scolaire, aux langues officielles et au statut des minorités francophones du pays. Elle effectue aussi une tâche inédite jusqu’à présent : mettre en relation cinq hebdomadaires et un quotidien afin de mieux saisir la complexité idéologique qui caractérise le débat public franco-ontarien. L’étude montre aussi l’existence d’un comportement « nationalitaire » dans la presse qui, nourrie de la mémoire du Canada français, sert de pierre angulaire pour les revendications des Franco-Ontariens.
Two sides of the story: the experiences and perspectives of child domestic workers and their employers in Bandung, Indonesia
Creators: name: Windred, Sarah
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2021
Subjects: child domestic workers
children's geographies
child labour
Indonesia

description: The phenomenon of child domestic workers in Indonesia represents a human rights issue of serious concern, due to the exploitation and abuse faced by many children, and the hidden nature of the work within employers’ home (MuhammedAlly 2005). The lack of legal protections for domestic workers in Indonesia, and pervasive cultural norms that suggest child domestic workers are treated ‘like family’, leave child domestic workers at the mercy of their employer (MuhammedAlly 2005). While there is a significant body of research exploring the experiences of Indonesian female migrant domestic workers employed overseas, in countries other than Indonesia (Barker 2018; HRW 2011; Nurchayati 2011; Parreñas et al. 2019; Silvey 2004; Ueno 2014; Yeoh & Huang 2010), there is a gap in the current body of literature regarding the lives of child domestic workers in Indonesia.
description: This research presents the findings from participatory child-focused research in Bandung, West Java, Indonesia, and seeks to understand the lived experiences and perspectives of child domestic workers (pembantu) and those of the employers of child domestic workers. The research focusses on 17 domestic workers between the ages of 14 and 17, to contribute to a growing body of research that acknowledges Indonesian marginalised children as active agents in the construction of their own lives (Beazley 2017). A variety of participatory research techniques were used in this study, designed to understand the children’s lives from their own perspective. Eight employers of child domestic workers were also interviewed.
SYNCHRONIZATION OF DELAYED INTEGER ORDER AND DELAYED FRACTIONAL ORDER RECURRENT NEURAL NETWORKS SYSTEM WITH ACTIVE SLIDING MODE CONTROL
Creators: name: Fatin Nabila Abd Latiff, Wan Ainun Mior Othman
Publisher: name: TuEngr Group
Year: 2020
Subjects: Chaotic synchronization
Chaotic Neural Networks (CNNs)
Sliding surface
RSA encryption
Double encryption
Cyber security, Cryptography technology.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 12, 11A12D: 1-15
Cholinergic control of sensory synaptic transmission in primary and nonprimary auditory thalamus of rat.
Creators: name: Mooney, David M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Biology, Neuroscience.

description: A large body of literature now indicates that behavior-dependent functional adaptations in the central auditory system are in large part regulated by a cholinergic modulatory input from the midbrain reticular formation. The central hypothesis behind this thesis is that acetylcholine is capable of modulating auditory synaptic transmission in a synaptic pathway-specific manner. The auditory thalamocortical system consists of primary (lemniscal) and nonprimary (nonlemniscal) auditory thalamocortical projections that originate from two segregated cell populations located in the ventral (MGv) and dorsal (MGd) divisions of the medial geniculate body (MGB). The two pathways are known to engage in different aspects of auditory function. A thalamic explant preparation was employed for the study, in which the parallel MGB pathways, together with their sensory afferents, can be maintained and accessed in vitro for comparative electrophysiological studies. The following summarizes the main findings described in this thesis. 1. When the MGB explant is persistently exposed to acetylcholine, the evoked sensory synaptic responses from MGv neurons consist almost exclusively of a single action potential and are able to follow high-frequency stimuli. In contrast, nonprimary or MGd neurons responded to sensory pathway stimulation with a stereotyped burst of action potentials which failed to follow a stimulation frequency higher than 5 Hz. 2. Intracellular recordings revealed that muscarine induces a slow membrane depolarization in ventral neurons, which helps EPSPs trigger single action potentials but prevents them from eliciting low threshold Ca2+ spike (LTS)-burst complexes. An opposite, membrane hyperpolarization response was observed in dorsal cells where muscarinic receptor activation promotes coupling between the EPSP and the LTS-burst. 3. Muscarine blocks a leak and a Ca2+-dependent K+ membrane conductance K(ca) in ventral MGB neurons whereas in dorsal cells it opens leak K+ channels and largely has no effect on K(ca). It is concluded that a differential modulatory mechanism mediated by muscarinic receptor activation helps create and maintain a fast synaptic responding mode in the primary thalamocortical pathway for high-fidelity sensory relay and a slower but robust bursting transmittal mechanism in the nonprimary pathway suitable for detection of sensory events and induction of long term synaptic plasticity in target cells.
"Loose my speche": Anne Locke's sonnets and the matrilineal Protestant poetic.
Creators: name: Morin-Parsons, Kel.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Literature, English.

description: This dissertation seeks to appreciate the English Reformation figure Anne Locke as an important poet, one responsible for producing the first sonnet sequence to be composed in English. Locke's 1560 sequence, A Meditation of a Penitent Sinner, consists of five prefatory and six main-body sonnets keyed to the popular 51st Psalm; it is found at the back of a volume of Jean Calvin's sermons translated by Locke. This dissertation discusses Locke's use of the motifs of voice and community in the Meditation to trace the Calvinist spiritual journey from sin to grace, and also looks at the manipulation of these ideas by two later Early Modern women poets, Mary Sidney, Countess of Pembroke, and Aemilia Lanyer. Locke's strategy for opening a space for women to speak of faith at a time when the power of voice was traditionally denied to them involves the destruction the most obvious earthly marker of gender, the body, and emphasises the vital importance to the Christian of voice. Locke reminds readers that it is, ultimately, the (genderless) voice that will cry out to God for mercy, of which all sinners, men and women, are equally in need. It is voice that will trace the journey of the sinner to the community of the godly, those souls, unburdened by the earthly restrictions of gender, to whom God has granted salvation. Mary Sidney, Countess of Pembroke, also worked with the 51st Psalm in her project to finish and expand the work of her brother, Sir Philip Sidney. Pembroke, writing near the end of the 16th century for a private audience of readers, shows a more comfortable, assured sense of the presence of grace in the life of her narrator; community has already been gained, and voice now expresses the soul's challenge to help others to find it. Finally, Aemilia Lanyer, whose Salve Deus Rex Judaeorum appeared in 1610, displays the most overtly "feminist" agenda of the three writers. She appropriates a self-consciously female narrative voice to gather a community of godly women around her---women who also enjoy a large measure of earthly power---in order to re-examine the story of Christ's Passion from a female perspective. Lanyer, perhaps more concerned with addressing earthly inequalities than with gaining the kingdom, is perhaps the least successful of the three women examined here in her project. Together, the three provide a fascinating triptych of Early Modern women's writing.
The Role of Thromboxane A2 Receptors in Diabetic Kidney Disease
Creators: name: Shaji, Roya
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: podocyte
diabetic kidney disease
thromboxane A2

description: Thromboxane receptor (TPr) activity is elevated in diabetes and contributes to complications of diabetic kidney disease (DKD). TPr blockade appears to have therapeutic potential. Several rodent models of DKD show attenuation of renal damage and proteinuria upon administration of the TPr antagonist, S18886. However, the cellular targets that underlie the injurious effects of TPr activation in DKD remain to be elucidated. A pilot study in our laboratory subjected a conditionally-immortalized mouse podocyte cell line to high glucose (25 mM D-glucose) and equibiaxial mechanical stretch (an in vitro simulator of increased glomerular capillary pressure associated with glomerular hyperfiltration in early diabetes). qRT-PCR revealed that exposure of podocytes to mechanical stretch (10% elongation) and high glucose for 6 hours yielded a 9-fold increase in TPr mRNA levels vs. controls (non-stretch, 5mM D-glucose + 25mM L-glucose) (p<0.05, n=5). We hypothesized that TPr expression and activity are increased in podocytes during the onset of DKD resulting in maladaptive effects on this key glomerular filtration barrier cell type. We showed that enhanced TPr signaling threatens podocytes viablility. Cultured podocytes treated with the TPr agonist, U-46619 (1 μM) for 24 hours are more vulnerable to apoptosis as quantified by Hoescht 33342 (20% cell death p<0.001, n=3) , TUNEL (30-fold increase, ns, n=3) and Annexin-V labeling (3-fold increase, p <0.001, n=3). To further support these in vitro findings, we developed a transgenic mouse with podocyte-specific overexpression of TPr. A construct consisting of a desensitization resistant mutant of the human TPr with both N- and C-terminal HA-epitope tags under the control of an 8.3 kb fragment of the immediate 5’ mouse NPHS1 promoter was cloned, isolated and injected into FVB/n oocytes that were implanted into pseudopregnant CD1 females. Founders were characterized for TPr transgene expression, and TPr transgene mRNA levels were detected by qRT-PCR. Our in vitro results suggest that increased TPr expression in podocytes of diabetic mice may contribute to filtration barrier damage and have important implications in the development and progression of DKD.
The Double-stranded RNA-binding Protein Staufen1 Negatively Regulates Skeletal Muscle Differentiation
Creators: name: Blais-Crépeau, Marie-Laure
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Staufen1
myogenesis
C2C12
differentiation

description: Staufen1 is a double-stranded RNA-binding protein known to be involved in the transport, localization, decay and increased translation of some mRNAs. The goal of the present study is to determine the role of Staufen1 during myogenic differentiation by characterizing the effects of Staufen1 over-expression in C2C12 cells. Immunofluorescence experiments revealed that Staufen1 over-expression causes a decrease in the fusion and differentiation indices and leads to the formation of myotubes with significantly fewer nuclei. We show, by western blot and qRT-PCR, that the protein expression of MyoD, myogenin and MyHC and the mRNA expression of MyoD, myogenin, Mef2A, Mef2C and p35 are significantly decreased during differentiation when Staufen1 is over-expressed. We then found that c-myc protein expression was increased during proliferation but that its mRNA expression remained unchanged. In this study we propose that Staufen1 negatively regulates skeletal muscle differentiation through the posttranscriptional regulation of c-myc, Mef2A, Mef2C and p35 transcripts.
SPEL Stormceptor & SPEL Filter Field Performance Evaluation Report
Creators: name: Pearson, Brian
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2014

description: The filtering capabilities of the SPEL Stormceptor and SPEL Filters in reducing TSS, TP and TN concentrations in stormwater runoff is a key factor in the continued growth of WSUD in Australia. The Nambour site has captured multiple stormwater events in which 12 events were analysed for performance efficiency. Some of these 12 events have produced valid water samples in accordance with the Stormwater BMP Monitoring Manual; however, overall the minimum parameter requirements were not met for this project. From these water samples, reductions in TSS and TP were found using the concentration removal efficiency method and the pollutant mass removal efficiency method. TN results showed negative reduction efficiencies for the SPEL Filters. Due to the site catchment area being predominantly new concrete, the inflow quantities of the substances being focussed on was less than required for most samples collected. More samples will be collected in future which will hopefully produce a higher level of inflow quantities to meet the minimum protocol requirements for results analysis.
Supplementary document for Parametric Comparison between Sparsity-Based and Deep Learning-Based Image Reconstruction of Super-Resolution Fluorescence Microscopy - 5297031.pdf
Creators: name: Chen, Yun
name: Chen, Junjie
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Image Processing

description: Supplemental document includes description to the supplemental code 1 and additional figures
Between Reality and Realism: CGI and Narrative in Hollywood Children's Films
Creators: name: Bernard, Kaitlin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Digital Media
Children's Media
Digital Cinema
CGI
Film
Narrative

description: This paper addresses many concepts and concerns related to the previously underexplored topic of CGI and narrative in Hollywood children’s films. Through an analysis of scenes from Harry Potter and the Philosopher’s Stone, The Chronicles of Narnia, The Golden Compass, The Spiderwick Chronicles, and Inkheart it demonstrates that CGI spectacle does not exist in opposition to narrative progression as some scholars have suggested. Instead, by drawing on theorists like Lefebvre and Furstenau (2002), this investigation asserts that belief in fictional realism is paramount to spectatorship. It is shown that CGI can be used in a way that respects realism in the Bazin tradition and continuity editing in order to allow the spectator to believe in the fictional reality of narrative events. This belief is then connected to the emotional engagement of the spectator by drawing on ideas from Smith’s (1994) structure of sympathy. The ultimate goal of this paper is to present a conceptualization of CGI that creates a stronger distinction between reality and film realism than previous literature has suggested.
Clinical evidence based review and systematic scientific review in the identification of malignant transformation of inverted papilloma
Creators: name: Long, Cai
name: Jabarin, Basel
name: Harvey, Alexandra
name: Ham, Jennifer
name: Javer, Amin
name: Janjua, Arif
name: Thamboo, Andrew
Publisher: name: BioMed Central
Year: 2020

description: Background: Inverted papilloma (IP) is an unusual type of benign tumor that has high recurrence rates and the potential to transform into squamous cell carcinomas (SCC). The mechanism of the transformation process from IP to IP-SCC is uncertain and there is no consensus regarding the best practice for IP-SCC detection. The goal of this study is to identify the best clinical methods to detect for IP-SCC. Methods: An evidence-based review was performed using Medline and Ovid to obtain all articles up to October 10th, 2019 pertaining to identification of IP malignant transformation. All manuscripts discussing clinical methods or biomarkers were included. Results: Based on clinical research studies, convoluted cerebriform pattern and apparent diffusion coefficient values on Magnetic Resonance Imaging (MRI) can help differentiate benign IP from SCC and increased SUVmax on PET/CT is associated with higher probability of malignancy although not as specific. No consensus about the best biomarker for IP-SCC has been reached among researchers and continues to be exploratory. Conclusion: Endoscopy with biopsy is the gold standard practice to identify IP-SCC; however, MRI is the preferred imaging modality to recognize malignant transformation in cases where biopsy is difficult. Multiple biomarkers have shown positive results, but no single indicator with clinical significance for monitoring malignant transformation process has been found.
Photochemical Strategies for the Synthesis of Advanced Materials
Creators: name: Billone, Paul
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: lithography
advanced materials
nanoparticles
photochemistry

description: This thesis describes the study of a variety of nanoscale materials and the development of novel synthetic strategies for their production. While the focus and bulk of this study have been directed specifically at subwavelength lithography, a significant portion of this thesis research involves nanoparticle synthesis, characterization, and functionalization. Put in very simple terms, optical lithography is a process where a beam of light, focused in a specific pattern, is used to generate a physical pattern on a solid substrate. This technology forms the basis for almost all microchip production in the world at the present time. As demand for faster and more powerful chips increases, the need to further miniaturize the patterns while minimizing cost has become very important. Multiple photochemical systems were developed in the search for non-reciprocal photochemistry at 193 nm to increase the resolution of lithographic processes at that wavelength. One approach, based on anthracene sensitization of sulfonium salts for acid generation, used photochemically reversible 4+4 aromatic cycloaddition reactions to introduce the non-linear photochemistry. A second approach took advantage of the photochemistry of N-methylphenothiazine and provided the first true example of a lithographically-relevant multi-photon acid generating process. Since all of the systems we studied used sulfonium salts as the acid generating species, we also looked at the photochemistry of the salts themselves. We evaluated the structural effects of the salts on their direct photochemistry and the implications for sensitized multi-photon photochemistry. We found that the identity of the anion plays a significant role in both processes and propose a new photochemical mechanism for acid generation that involves a charge transfer excitation process. We also describe the synthesis and characterization of novel fluorescent silver nanoparticles, both in solution and polymer films. We show that the fluorescent images can be patterned easily and preliminary results show that photolithography based on nanoparticle formation may be possible. This latter approach could provide a facile route to nanoparticle-embedded functional materials. This work with nanoparticles was inspired partly by earlier work, also presented herein, on semiconductor nanoparticles and their interactions with disulfide ligands.
title: Learning from previous work and finding synergies in the domains of public and environmental health
title: Learning from previous work and finding synergies in the domains of public and environmental health
titleType: AlternativeTitle
Creators: name: David, Madlen
name: Kolossa-Gehring, Marike
name: Reiber, Lena
name: Schwedler, Gerda
Publisher: name: My University
Year: 2020
Subjects: Human-Biomonitoring
Umwelthygiene
Volksgesundheit

description: Background During the last decade, the European Union initiated several projects in the domains of public and environmental health. Within this framework, BRIDGE Health (Bridging Information and Data Generation for Evidence-based Health policy and Research) and HBM4EU (European human biomonitoring initiative) have been implemented. Whereas, the focus of BRIDGE Health was towards a sustainable and integrated health information system (HIS), the aim of HBM4EU is to improve evidence of the internal exposure of European citizens to environmental chemicals by human biomonitoring (HBM) and the impact of internal exposure on health. As both, environmental and public health determinants are important for health promotion, disease prevention and policy, BRIDGE Health and HBM4EU have overlapping aims and outcomes. In order to improve health information regarding public health and environmental health issues, best use and exchange of respective networks and project results is necessary. Methods Both projects have implemented health information (HI) and HBM tasks in order to provide adequate environmental and public health information of the European population. Synergies of the projects were identified in the working progress and because of overlapping networks and experts a focused analysis of both projects was envisaged. This paper elaborates on the aims and outcomes of both projects and the benefit of merging and channelling research results for the use of better health information and policy making that may be of relevance for any other project in these research fields. Results The need for focused exchanges and collaborations between the projects were identified and benefits of exchanges were highlighted for the specific areas of indicator development, linkage of data repositories and the combination of HBM studies and health examination surveys (HES). Further recommendations for a European wide harmonisation among different tasks in the fields of public health and environmental health are being developed. Conclusions Lessons learned from HBM4EU and BRIDGE Health show that continuous efforts must be undertaken, also by succeeding projects, to guarantee the exchange between public health and environmental health issues. Networks covering both are essential to provide better evidence of knowledge. The experiences from BRIDGE Health and HBM4EU give a valuable input for any future activity in these domains. Avoiding overlaps and streamlining further exchange of public health and environmental health contributes to best use of research results and allows to develop new strategies and tools for improvement of health information and thus enhances people's health and well-being. © The Author(s).
An alternative strategy of Strategic Global Entrepreneurship (SGE): an integrated approach of Business-Commercial (BC) and Social-Community (SC) entrepreneurship as a viable strategy within for-profits, not-for-profits and governmental stakeholders
Creators: name: Meewella, John Isaac Graham
Publisher: name: Swinburne
Year: 2024

description: This thesis explores various entrepreneurial strategies available to manage emerging organisations. Business-Commercial Entrepreneurship and Social-Community Entrepreneurship have traditionally existed within organisations in partial or 'piece-meal' approaches. While the concept of Entrepreneurship dates back hundreds of years, however in theoretical concepts there is limited evidence to suggest it being used as a 'driving- integrated and sustainable strategy'. Academic/ empirical research has neglected/ has limited applications of holistic-integrated approaches of entrepreneurship. Till now, Business-Commercial Entrepreneurship has focused mainly on 'commercial' missions; and Social-Community Entrepreneurship has primarily concentrated on 'social' missions. Hence these two approaches in a majority of the cases have been adopted in isolated frameworks. Within this study, the research addresses three questions: i) What are viable entrepreneurial strategies for future organizations? ii) Under what conditions are these entrepreneurial strategies most effective? & iii) What are the frameworks for utilising such strategies in a global settings? As part of this study, the author was personally involved in several groups of companies; and the author and his wife- Lily Meewella co-founded Aspire Solutions Group – a real-life organization pursuing strategic global entrepreneurial directions. Data was collected using: case study methodology, observation, anthropological style research and unstructured questionnaires. Findings indicate that integrated approaches are better advocates in managing emerging organisations, operating within business, not-for-profit and governmental domains. It is argued that the lack of 'integrated' organisational models in literature as well as its application empirically in the contemporary global context is to some degree a result of mis-conceptualization, misunderstanding, and problems with implementation rather than with the actual principle concepts of Business-Commercial Entrepreneurship and/ or Social-Community Entrepreneurship. Strategic Global Entrepreneurship combines the strengths of both commercial and social missions in an integrated holistic framework. SGE is presented as the way forward for stakeholders operating within business, not-for-profit and governmental domains.