cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene
Creators: name: Van Blitterswijk, Marka
name: Mullen, Bianca
name: Wojtas, Aleksandra
name: Heckman, Michael G.
name: Diehl, Nancy N.
name: Baker, Matthew C.
name: DeJesus-Hernandez, Mariely
name: Brown, Patricia H.
name: Murray, Melissa E.
name: Hsiung, Ging-Yuek R.
name: Stewart, Heather
name: Karydas, Anna M.
name: Finger, Elizabeth
name: Kertesz, Andrew
name: Bigio, Eileen H.
name: Weintraub, Sandra
name: Mesulam, Marsel
name: Hatanpaa, Kimmo J.
name: White, Charles L.
name: Neumann, Manuela
name: Strong, Michael J.
name: Beach, Thomas G.
name: Wszolek, Zbigniew K.
name: Lippa, Carol
name: Caselli, Richard
name: Petrucelli, Leonard
name: Josephs, Keith A.
name: Parisi, Joseph E.
name: Knopman, David S.
name: Petersen, Ronald C.
name: Mackenzie, Ian R.
name: Seeley, William W.
name: Grinberg, Lea T.
name: Miller, Bruce L.
name: Boylan, Kevin B.
name: Graff-Radford, Neill R.
name: Boeve, Bradley F.
name: Dickson, Dennis W.
name: Rademakers, Rosa
Publisher: name: BioMed Central
Year: 2015

description: Background. Hexanucleotide repeat expansions in chromosome 9 open reading frame 72 (C9ORF72) are causative for frontotemporal dementia (FTD) and motor neuron disease (MND). Substantial phenotypic heterogeneity has been described in patients with these expansions. We set out to identify genetic modifiers of disease risk, age at onset, and survival after onset that may contribute to this clinical variability. Results We examined a cohort of 330 C9ORF72 expansion carriers and 374 controls. In these individuals, we assessed variants previously implicated in FTD and/or MND; 36 variants were included in our analysis. After adjustment for multiple testing, our analysis revealed three variants significantly associated with age at onset (rs7018487 [UBAP1; p-value = 0.003], rs6052771 [PRNP; p-value = 0.003], and rs7403881 [MT-Ie; p-value = 0.003]), and six variants significantly associated with survival after onset (rs5848 [GRN; p-value = 0.001], rs7403881 [MT-Ie; p-value = 0.001], rs13268953 [ELP3; p-value = 0.003], the epsilon 4 allele [APOE; p-value = 0.004], rs12608932 [UNC13A; p-value = 0.003], and rs1800435 [ALAD; p-value = 0.003]). Conclusions Variants identified through this study were previously reported to be involved in FTD and/or MND, but we are the first to describe their effects as potential disease modifiers in the presence of a clear pathogenic mutation (i.e. C9ORF72 repeat expansion). Although validation of our findings is necessary, these variants highlight the importance of protein degradation, antioxidant defense and RNA-processing pathways, and additionally, they are promising targets for the development of therapeutic strategies and prognostic tests.
Low Gain Avalanche Detectors with Good Time Resolution Developed by IHEP and IME for ATLAS HGTD project
Creators: name: Zhao, Mei
name: Jia, Xuewei
name: Wu, Kewei
name: Yang, Tao
name: Li, Mengzhao
name: Fan, Yunyun
name: Yan, Gangping
name: Wang, Wei
name: Li, Mengran
name: Xu, Gaobo
name: Ding, Mingzheng
name: Yin, Huaxiang
name: Luo, Jun
name: Li, Junfeng
name: Shi, Xin
name: Liang, Zhijun
name: da Costa, João Guimarães
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: This paper shows the simulation and test results of 50um thick Low Gain Avalanche Detectors (LGAD) sensors designed by the Institute of High Energy Physics (IHEP) and fabricated by the Institute of Microelectronics of the Chinese Academy of Sciences (IME). Three wafers have been produced with four different gain layer implant doses each. Different production processes, including variation in the n++ layer implant energy and carbon co-implantation were used. Test results show that the IHEP-IME sensors with the higher dose of gain layer have lower breakdown voltages and higher gain layer voltages from capacitance-voltage properties, which are consistent with the TCAD simulation. Beta test results show that the time resolution of IHEP-IME sensors is better than 35ps when operated at high voltage and the collected charges of IHEP-IME sensors are larger than 15fC before irradiation, which fulfill the required specifications of sensors before irradiations for the ATLAS HGTD project.
description: 11 pages,8 figures
Ungappable edge theories with finite dimensional Hilbert spaces
Creators: name: Ganeshan, Sriram
name: Levin, Michael
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct a new class of edge theories for a family of fermionic Abelian topological phases with $K$-matrices of the form $K = \begin{pmatrix} k_1 & 0 \\ 0 & - k_2 \end{pmatrix}$, where $k_1, k_2 > 0$ are odd integers. Our edge theories are notable for two reasons: (i) they have finite dimensional Hilbert spaces (for finite sized systems) and (ii) depending on the values of $k_1, k_2$, some of the edge theories describe boundaries that cannot be gapped by any local interaction. The simplest example of such an ungappable boundary occurs for $(k_1, k_2) = (1, 3)$, which is realized by the $ν= 2/3$ FQH state. We derive our edge theories by starting with the standard chiral boson edge theory, consisting of two counterpropagating chiral boson modes, and then introducing an array of pointlike impurity scatterers. We solve this impurity model exactly in the limit of infinite impurity scattering, and we show that the energy spectrum consists of a gapped phonon spectrum together with a ground state degeneracy that scales exponentially with the number of impurities. This ground state subspace forms the Hilbert space for our edge theory. We believe that similar edge theories can be constructed for any Abelian topological phase with vanishing thermal Hall coefficient, $κ_H = 0$.
description: 22 pages, 8 figures, added Appendix B on electron operators
title: 01_0737
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Boosting the Quantum State of a Cavity with Floquet Driving
Creators: name: Long, David M.
name: Crowley, Philip J. D.
name: Kollár, Alicia J.
name: Chandran, Anushya
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The striking nonlinear effects exhibited by cavity QED systems make them a powerful tool in modern condensed matter and atomic physics. A recently discovered example is the quantized pumping of energy into a cavity by a strongly-coupled, periodically-driven spin. We uncover a remarkable feature of these energy pumps: they coherently translate, or boost, a quantum state of the cavity in the Fock basis. Current optical cavity and circuit QED experiments can realize the required Hamiltonian in a rotating frame. Boosting thus enables the preparation of highly-excited non-classical cavity states in near-term experiments.
description: 6 pages, 4 figures + 6 pages, 6 figures; (v2) Clarifications on experimental considerations, including an additional appendix on the lab frame evolution
Role of anomalous symmetry in 0-$π$ qubits
Creators: name: Egusquiza, I. L.
name: Iñiguez, A.
name: Rico, E.
name: Villarino, A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present an exact full symmetry analysis of the 0-$π$ superconducting circuit. We identify points in control parameter space of enhanced anomalous symmetry, which imposes robust twofold degeneracy of its ground state, that is for all values of the energy parameters of the model. We show, both analytically and numerically, how this anomalous symmetry is maintained in the low-energy sector, thus providing us with a strong candidate for robust qubit engineering.
description: 23 pages, 3 figures. Published version
SMART-Plant_IWARR2019_Advanced composting and bio-drying as an opportunity to recover material and energetic resources from sludges
Creators: name: N., Guerra
name: M., Mora
name: L., Pelaz
name: J., Ovejero
name: L., Llenas
name: B., Puyuelo
name: J., Colón
name: S., Ponsá
Publisher: name: Zenodo
Year: 2020
Subjects: biofertilisers
biomass fuel
resource recovery

description: Abstract:
 The need to change the current paradigm from linear economy to circular economy
 makes the recovery of resources from waste effluents one of the current and future
 technological priorities. In this context, sewage sludge represents a great challenge
 and at the same time a great opportunity for the recovery of resources, both material,
 and energy. Within the framework of the H2020 SMART Plant project, BETA Tech.
 Centre is developing two technologies to maximise resource recovery from different
 types of sludge. Firstly, phosphorus-rich biofertilisers are being produced through
 advanced dynamic composting processes treating sludge from EBPR and SCENA
 processes. Secondly, cellulose-rich sludge is being treated through biodrying
 processes to produce biomass fuel with a calorific value similar to that of pine chips.
Trapping and binding by dephasing
Creators: name: Mukherjee, Kaustav
name: Poddar, Siddhartha
name: Wüster, Sebastian
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The binding and trapping of particles usually rely on conservative forces, described by unitary quantum dynamics. We show that both can also arise solely from spatially dependent dephasing, the simplest type of decoherence. This can be based on continuous weak position measurements in only selected regions of space, for which we propose a practical realisation. For a single particle, we demonstrate a quantum particle-in-the-box based on dephasing. For two particles, we demonstrate their binding despite repulsive interactions, if their molecular states are dephased at large separations only. Both mechanisms are experimentally accessible, as we show for an example with Rydberg atoms in a cold gas background.
description: 9 pages, 8 figures
title: Privacy and availability needs regarding user preferences for Smart Availability Assistant – towards a digitally enabled work life balance
Creators: name: Saternus, Zofia
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: availability management
subject: smart assistant
subject: information privacy
subject: privacy concerns

description: The use of communication technologies (CTs) enables blurring the traditional boundaries between work and private life. Many employers are worried about this situation and addressed those issues with different technological and organizational approaches. The goal of our research is to introduce improved enterprise availability management by developing an employee-friendly technological solution that actually reflects the variety of employees’ availability needs. Due to the overall aim of broadening and bridging research on an availability management, results of a quantitative study (N=821) insights into the management of individuals’ availability and key requirements regarding the development of a Smart Availability Assistant. In general, it became apparent that to appropriately design this kind of smart assistant we must not only recognize the heterogeneity of peoples’ availability preferences but also identify and meet employees’ privacy expectations by use of a Smart Availability Assistant.
Dense matter equation of state and phase transitions from a Generalized Skyrme model
Creators: name: Adam, Christoph
name: Martin-Caro, Alberto Garcia
name: Huidobro, Miguel
name: Vazquez, Ricardo
name: Wereszczynski, Andrzej
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Skyrmion crystals are the field configurations which minimize the energy per baryon in the infinitely large topological charge sector of the Skyrme model, at least for sufficiently high density. They are, therefore, an important tool to describe the ground state of cold, symmetric nuclear matter at high density regimes. In this work, we analyze different crystalline phases and the existence of phase transitions between them within the generalized Skyrme model, with the ultimate goal of describing symmetric nuclear matter in a wide regime of densities. Furthermore, we propose a new energy-minimizing phase for densities lower than the nuclear saturation point ($n_0$) which also presents a good qualitative behavior in the zero density limit, thereby improving the description of strongly interacting matter in the region $n
description: 16 pages, 10 figures; v2: presentation slightly improved, some references added
Single point mutation in Rabenosyn-5 in a female with intractable seizures and evidence of defective endocytotic trafficking
Creators: name: Stockler, Sylvia
name: Corvera, Silvia
name: Lambright, David
name: Fogarty, Kevin
name: Nosova, Ekaterina
name: Leonard, Deborah
name: Steinfeld, Robert
name: Ackerley, Cameron
name: Shyr, Casper
name: Au, Nicolas
name: Selby, Kathrin
name: Van Allen, Margot
name: Vallance, Hilary
name: Wevers, Ron
name: Watkins, David
name: Rosenblatt, David
name: Ross, Colin J.
name: Conibear, Elizabeth
name: Wasserman, Wyeth W.
name: Van Karnebeek, Clara
Publisher: name: BioMed Central
Year: 2015

description: Background: We report a 6.5 year-old female with a homozygous missense mutation in ZFYVE20, encoding Rabenosyn-5 (Rbsn-5), a highly conserved multi-domain protein implicated in receptor-mediated endocytosis. The clinical presentation includes intractable seizures, developmental delay, microcephaly, dysostosis, osteopenia, craniofacial dysmorphism, macrocytosis and megaloblastoid erythropoiesis. Biochemical findings include transient cobalamin deficiency, severe hypertriglyceridemia upon ketogenic diet, microalbuminuria and partial cathepsin D deficiency. Methods and results Whole exome sequencing followed by Sanger sequencing confirmed a rare (frequency:0.003987) homozygous missense mutation, g.15,116,371 G > A (c.1273G > A), in ZFYVE20 resulting in an amino acid change from Glycine to Arginine at position 425 of the Rbsn protein (p.Gly425Arg), as the only mutation segregating with disease in the family. Studies in fibroblasts revealed expression and localization of Rbsn-5G425R in wild-type manner, but a 50% decrease in transferrin accumulation, which is corrected by wild-type allele transfection. Furthermore, the patient’s fibroblasts displayed an impaired proliferation rate, cytoskeletal and lysosomal abnormalities. Conclusion These results are consistent with a functional defect in the early endocytic pathway resulting from mutation in Rbsn-5, which secondarily disrupts multiple cellular functions dependent on endocytosis, leading to a severe multi-organ disorder.
title: Privacy by Design Architecture Composed of Identity Agents Decentralizing Control over Digital Identity
Creators: name: Toth, Kalman C.
name: Cavoukian, Ann
name: Anderson-Priddy, Alan
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: privacy
subject: privacy by design
subject: digital identity
subject: authentication
subject: verification
subject: security.

description: Proposed is an identity architecture that satisfies the principles of privacy by design, decentralizes control over digital identity from providers to users, mitigates breach and impersonation risks, and reduces dependency on remote access passwords. The architecture is composed of interoperating identity agents that work on behalf of their owners and deploy digital identities that are virtualized to look and behave like identities found in one’s wallet and contacts list. Encapsulating authentication data, identity agents strongly bind owners to their digital identities and private keys enabling them to prove who they are, protect their private data, secure transactions, conduct identity proofing, and reliably delegate consent. Identity agents also off-load application services from identity-related and privacy-related tasks. A gestalt privacy by design process has been used to discover the architecture’s privacy requirements and design elements and systematically reason about how the design elements satisfy the privacy requirements. Identity-related functionality has been intentionally compartmentalized within identity agents to focus development on creating trustworthy software. A reference model for development derived from the described identity architecture is proposed.
Eigenvalue repulsions in the quasinormal spectra of the Kerr-Newman black hole
Creators: name: Dias, Oscar J. C.
name: Godazgar, Mahdi
name: Santos, Jorge E.
name: Carullo, Gregorio
name: Del Pozzo, Walter
name: Laghi, Danny
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study the gravito-electromagnetic perturbations of the Kerr-Newman (KN) black hole metric and identify the two $-$ photon sphere and near-horizon $-$ families of quasinormal modes (QNMs) of the KN black hole, computing the frequency spectra (for all the KN parameter space) of the modes with the slowest decay rate. We uncover a novel phenomenon for QNMs that is unique to the KN system, namely eigenvalue repulsion between QNM families. Such a feature is common in solid state physics where \eg it is responsible for energy bands/gaps in the spectra of electrons moving in certain Schrödinger potentials. Exploiting the enhanced symmetries of the near-horizon limit of the near-extremal KN geometry we also develop a matching asymptotic expansion that allows us to solve the perturbation problem using separation of variables and provides an excellent approximation to the KN QNM spectra near extremality. The KN QNM spectra here derived are required not only to account for the gravitational emission in astrophysical environments, such as the ones probed by LIGO, Virgo and LISA, but also allow to extract observational implications on several new physics scenarios, such as mini-charged dark-matter or certain modified theories of gravity, degenerate with the KN solution at the scales of binary mergers.
description: 9 pages, 2 figures
title: IdToken: a new decentralized approach to digital identi-ty
Creators: name: Talamo, Edoardo
name: Pennacchi, Alma
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: Blockchain non fungible token
subject: blockchain
subject: digital identity
subject: idtoken
subject: security
subject: privacy
subject: idchain
subject: hyperledger indy

description: The ability to store and share digital data offers benefits that the digitization of information has become a growing trend but has raised questions about the security of personal data. There have been countless high-profile hacks and personal information leaks. Furthermore users don’t (and shouldn’t) always trust an external server of a third party to store their personal data. Blockchain tries to offer a compelling solution to the problem of combining accessibility with privacy and security. Records can be held securely, using end-to-end encryption, and yet openly authenticated so that data can still be trusted as reliable. This project goes deeper in this solution thanks to an innovative idea and development of a new kind of blockchain non fungible token specifically created to store and manage digital identities and sensible data. It has the potential to resolve issues blockchain alone was starting to approach and improves security, privacy and accessibility.
title: Data Protection Impact Assessment in Identity Control Management with a Focus on Biometrics
Creators: name: Bisztray, Tamas
name: Gruschka, Nils
name: Mavroeidis, Vasileios
name: Fritsch, Lothar
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: data protection
subject: privacy
subject: impact assessment
subject: GDPR
subject: DPIA
subject: identity management
subject: biometrics

description: Privacy issues concerning biometric identification are becoming increasingly relevant due to their proliferation in various fields, including identity and access control management (IAM). The General Data Protection Regulation (GDPR) requires the implementation of a data protection impact assessment for privacy critical systems. In this paper, we analyse the usefulness of two different privacy impact assessment frameworks in the context of biometric data protection. We use experiences from the SWAN project that processes four different biometric characteristics for authentication purposes. The results of this comparison elucidate how useful these frameworks are in identifying sector-specific privacy risks related to IAM and biometric identification.
Hermitian and non-Hermitian perturbations of chiral Gaussian $β$-ensembles
Creators: name: Alpan, Gökalp
name: Kozhan, Rostyslav
Publisher: name: arXiv
Year: 2021
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We compute the joint eigenvalue distribution for the rank one Hermitian and non-Hermitian perturbations of chiral Gaussian $β$-ensembles ($β>0$) of random matrices.
New directions in engineering education: developing creative and responsible product design engineers
Creators: name: de Vere, Ian
Publisher: name: Swinburne
Year: 2024

description: New product development has been described as an industry that requires the integrated skill sets of both Industrial Design and Mechanical Engineering. However, designers typically lack the technical depth and analytical skills of an engineer, whilst engineers lack the design acumen and user-centred approach of the industrial designer. This lack of cross-discipline synergy may result in inefficiencies and missed opportunities, and be detrimental to the new product development process. Design and engineering faculties now recognise the need to train graduates who are more suited to cross-disciplinary roles in product design. One such approach is the new engineering discipline of Product Design Engineering (PDE), an engineering qualification that results from the integration of industrial design and mechanical engineering curriculum. The pedagogical integration of these disparate professions has potential to lead a new direction in engineering education, by fostering creativity, introducing vital social and environmental agendas, expanding learning opportunities through design project-based learning and developing human-centred design acumen. This research examines the product design industry and identifies key graduate attributes for engineers engaged in new product development. It discovers critical areas of concern in engineering education, establishing the need for new engineering pedagogy. It also explores the integration of design into engineering curricula as a means to enhance the product design capabilities of engineering students. The research then investigates the emergence, impact and relevance of the Product Design Engineering pedagogy, as an appropriate response to both the expectations of new product development industries, and the educational reform mandated by global engineering regulatory organisations. This research, as the first examination of the Product Design Engineering paradigm, represents an original contribution to knowledge in respect to identification, analysis and documentation of an emerging global trend in engineering education. It makes an argument for the inclusion of design and creativity curricula in engineering education and validates Product Design Engineering as an appropriate response to industry and regulatory expectations.
title: Towards Universal Login
Creators: name: Hühnlein, Detlef
name: Hühnlein, Tina
name: Hornung, Gerrit
name: Strack, Hermann
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: SAML
subject: OpenID Connect
subject: FIDO
subject: eIDAS

description: The present paper provides an overview of existing protocols and infrastructures for Identity Management on the Internet and discusses potential paths towards integrating the different approaches in a user centric manner into a “Universal Login” infrastructure, which allows Users to manage their authentication preferences and Service Providers to integrate with Identity Providers in an easy manner.
Spreading of fake news, competence, and learning: kinetic modeling and numerical approximation
Creators: name: Franceschi, Jonathan
name: Pareschi, Lorenzo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Numerical Analysis (math.NA)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: The rise of social networks as the primary means of communication in almost every country in the world has simultaneously triggered an increase in the amount of fake news circulating online. This fact became particularly evident during the 2016 U.S. political elections and even more so with the advent of the COVID-19 pandemic. Several research studies have shown how the effects of fake news dissemination can be mitigated by promoting greater competence through lifelong learning and discussion communities, and generally rigorous training in the scientific method and broad interdisciplinary education. The urgent need for models that can describe the growing infodemic of fake news has been highlighted by the current pandemic. The resulting slowdown in vaccination campaigns due to misinformation and generally the inability of individuals to discern the reliability of information is posing enormous risks to the governments of many countries. In this research using the tools of kinetic theory we describe the interaction between fake news spreading and competence of individuals through multi-population models in which fake news spreads analogously to an infectious disease with different impact depending on the level of competence of individuals. The level of competence, in particular, is subject to an evolutionary dynamic due to both social interactions between agents and external learning dynamics. The results show how the model is able to correctly describe the dynamics of diffusion of fake news and the important role of competence in their containment.
Between Two Fern Genomes
Creators: name: Sessa, Emily B.
name: Banks, Jo A.
name: Barker, Michael S.
name: Der, Joshua P.
name: Duffy, Aaron M.
name: Graham, Sean W.
name: Hasebe, Mitsuyasu
name: Langdale, Jane
name: Li, Fay-Wei
name: Marchant, D. B.
name: Pryer, Kathleen M.
name: Rothfels, Carl J.
name: Roux, Stanley J.
name: Salmi, Mari L.
name: Sigel, Erin M.
name: Soltis, Douglas E.
name: Soltis, Pamela S.
name: Stevenson, Dennis W.
name: Wolf, Paul G.
Publisher: name: BioMed Central
Year: 2016

description: Ferns are the only major lineage of vascular plants not represented by a sequenced nuclear genome. This lack of genome sequence information significantly impedes our ability to understand and reconstruct genome evolution not only in ferns, but across all land plants. Azolla and Ceratopteris are ideal and complementary candidates to be the first ferns to have their nuclear genomes sequenced. They differ dramatically in genome size, life history, and habit, and thus represent the immense diversity of extant ferns. Together, this pair of genomes will facilitate myriad large-scale comparative analyses across ferns and all land plants. Here we review the unique biological characteristics of ferns and describe a number of outstanding questions in plant biology that will benefit from the addition of ferns to the set of taxa with sequenced nuclear genomes. We explain why the fern clade is pivotal for understanding genome evolution across land plants, and we provide a rationale for how knowledge of fern genomes will enable progress in research beyond the ferns themselves.
Incorporating global dynamics to improve the accuracy of disease models: Example of a COVID-19 SIR model
Creators: name: AlQadi, Hadeel
name: Bani-Yaghoub, Majid
Publisher: name: arXiv
Year: 2021
Subjects: subject: Applications (stat.AP)
subject: Physics and Society (physics.soc-ph)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Mathematical models of infectious diseases exhibit robust dynamics such as stable endemic or a disease-free equilibrium, or convergence of the solutions to periodic epidemic waves. The present work shows that the accuracy of such dynamics can be significantly improved by incorporating both local and global dynamics of the infection in disease models. To demonstrate improved accuracies, we extended a standard Susceptible-Infected-Recovered (SIR) model by incorporating global dynamics of the COVID-19 pandemic. The extended SIR model assumes three possibilities for the susceptible individuals traveling outside of their community: They can return to the community without any exposure to the infection, they can be exposed and develop symptoms after returning to the community, or they can be tested positive during the trip and remain quarantined until fully recovered. To examine the predictive accuracies of the extended SIR model, we studied the prevalence of the COVID-19 infection in Kansas City, Missouri influenced by the COVID-19 global pandemic. Using a two-step model-fitting algorithm, the extended SIR model was parameterized using the Kansas City, Missouri COVID-19 data during March to October 2020. The extended SIR model significantly outperformed the standard SIR model and revealed oscillatory behaviors with an increasing trend of infected individuals. In conclusion, the analytics and predictive accuracies of disease models can be significantly improved by incorporating the global dynamics of the infection in the models.
description: 27 pages, 6 figures
Bimodal Approach for Noise Figures of Merit Evaluation in Quantum-Limited Josephson Traveling Wave Parametric Amplifiers
Creators: name: Fasolo, L.
name: Barone, C.
name: Borghesi, M.
name: Carapella, G.
name: Caricato, A. P.
name: Carusotto, I.
name: Chung, W.
name: Cian, A.
name: Di Gioacchino, D.
name: Enrico, E.
name: Falferi, P.
name: Faverzani, M.
name: Ferri, E.
name: Filatrella, G.
name: Gatti, C.
name: Giachero, A.
name: Giubertoni, D.
name: Greco, A.
name: Kutlu, C.
name: Leo, A.
name: Ligi, C.
name: Livreri, P.
name: Maccarrone, G.
name: Margesin, B.
name: Maruccio, G.
name: Matlashov, A.
name: Mauro, C.
name: Mezzena, R.
name: Monteduro, A. G.
name: Nucciotti, A.
name: Oberto, L.
name: Pagano, S.
name: Pierro, V.
name: Piersanti, L.
name: Rajteri, M.
name: Rettaroli, A.
name: Rizzato, S.
name: Semertzidis, Y. K.
name: Uchaikin, U.
name: Vinante, A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The advent of ultra-low noise microwave amplifiers revolutionized several research fields demanding quantum-limited technologies. Exploiting a theoretical bimodal description of a linear phase-preserving amplifier, in this contribution we analyze some of the intrinsic properties of a model architecture (i.e., an rf-SQUID based Josephson Traveling Wave Parametric Amplifier) in terms of amplification and noise generation for key case study input states (Fock and coherents). Furthermore, we present an analysis of the output signals generated by the parametric amplification mechanism when thermal noise fluctuations feed the device.
description: 5 pages, 6 figures
Radio Power from Direct-Collapse Black Holes
Creators: name: Whalen, Daniel J.
name: Mezcua, Mar
name: Patrick, Samuel J.
name: Meiksin, Avery
name: Latif, Muhammad A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Direct-collapse black holes (DCBHs) forming at $z \sim$ 20 are currently the leading candidates for the seeds of the first quasars, over 200 of which have now been found at $z >$ 6. Recent studies suggest that DCBHs could be detected in the near infrared by the James Webb Space Telescope, Euclid, and the Roman Space Telescope. However, new radio telescopes with unprecedented sensitivities such as the Square Kilometer Array (SKA) and the Next-Generation Very Large Array (ngVLA) may open another window on the properties of DCBHs in the coming decade. Here we estimate the radio flux from DCBHs at birth at $z =$ 8 - 20 with several fundamental planes of black hole accretion. We find that they could be detected at $z \sim$ 8 by the SKA-FIN all-sky survey. Furthermore, SKA and ngVLA could discover 10$^6$ - 10$^7$ $M_{\odot}$ BHs out to $z \sim$ 20, probing the formation pathways of the first quasars in the Universe.
description: 6 pages. 4 figures, accepted by ApJL
Exact solution of a boundary time-crystal phase transition: time-translation symmetry breaking and non-Markovian dynamics of correlations
Creators: name: Carollo, Federico
name: Lesanovsky, Igor
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The breaking of the continuous time-translation symmetry manifests, in Markovian open quantum systems, through the emergence of non-stationary dynamical phases. Systems that display nonequilibrium transitions into these phases are referred to as time-crystals, and they can be realized, for example, in many-body systems governed by collective dissipation and long-ranged interactions. Here, we provide a complete analytical characterization of a boundary time-crystal phase transition. This involves exact expressions for the order parameter and for the dynamics of quantum fluctuations, which, in the time-crystalline phase, remains asymptotically non-Markovian as a consequence of the time-translation symmetry breaking. We demonstrate that boundary time-crystals are intrinsically critical phases, where fluctuations exhibit a power-law divergence with time. Our results show that a dissipative time-crystal phase is far more than merely a classical non-linear and non-stationary (limit cycle) dynamics of a macroscopic order parameter. It is rather a genuine many-body phase where the properties of correlations distinctly differs from that of stationary ones.
description: 13 pages, 2 figures
Big Data Pilot Demo Days: I-BiDaaS Application to the Financial Sector Webinar
Creators: name: Dusan Jakovetic
name: Pozuelo, Ramon Martin De
Publisher: name: Zenodo
Year: 2020
Subjects: Big Data as a Self-Service
Industrial-Driven Big Data Applications
Lessons Learned

description: Hosted by BDV PPP. BigDataStack, I-BiDaaS, Track & Know and Policy Cloud join forces in a series of online demonstrations of innovative Big Data Technologies unlocking the potential of various applications. The kick-off webinar of the Big Data Pilot Demo Days series under BDV PPP, I-BiDaaS Application to the Financial Sector, was held on May 21st. The main goal of this big data pilot webinar was to demonstrate in a step by step fashion the I-BiDaaS self-service solution and its application to the banking sector. Watch the I-BiDaaS Application to the Financial Sector Webinar recordings: Introduction to the series of webinars. - Marieke Willems (Trust-IT, BigDataStack) Introduction to the I-BiDaaS project - Dusan Jakovetic (UNSPMF) CaixaBank’s Pitches: Setting the requirements - Ramon Martin de Pozuelo (CaixaBank) I-BiDaaS architecture: a Scientific & Technical view and how it addresses the requirements set by the CaixaBank pilot study - Dusan Jakovetic (UNSPMF) Step by Step demonstration of the I-BiDaaS solution and its application to the banking sector - Ramon Martin de Pozuelo (CaixaBank)
description: Watch the full webinar in our YouTube channel: https://youtu.be/omhDsRkjI94
A cold electron-impact ion source driven by a photo-cathode -- New opportunities for the delivery of radioactive molecular beams?
Creators: name: Ballof, J.
name: Au, M.
name: Barbero, E.
name: Chrysalidis, K.
name: Düllmann, Ch. E.
name: Fedosseev, V.
name: Granados, E.
name: Heinke, R.
name: Marsh, B.
name: Owen, M.
name: Rothe, S.
name: Stora, T.
name: Yakushev, A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The thick-target ISOL (Isotope mass Separation OnLine) method provides beams of more than 1000 radionuclides of 74 elements. The method is well established for elements with sufficiently high volatility at ca. 2000 °C. To extract non-volatile elements the formation of a volatile molecule is required. While successful in some cases (e.g. carbon or boron), most of these elements are not yet available as ISOL beam. A variety of volatile carrier molecules has been proposed for all elements produced in the target material, but their probability of survival during the extraction and ionization process is often limited by the high temperatures required for isotope diffusion in the thick targets and for ion source operation. While cold target concepts have already been proposed, the normal mode of operation of the typically used Versatile Arc Discharge Ion Source (VADIS) with a hot cathode is not well suited. Here, we report about first measurements with an electron-impact ion source operated at ambient temperature using electrons that were liberated via the photo-electric effect from a copper cathode.
The role of surface spin polarization on ceria-supported Pt nanoparticles
Creators: name: Kang, Byungkyun
name: Vincent, Joshua L.
name: Crozier, Peter A.
name: Zhu, Qiang
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: In this work, we employ first-principles simulations to investigate the spin polarization of CeO$_2$-(111) surface and its impact on interactions between a ceria support and Pt nanoparticles. For the first time, we report that the CeO$_2$-(111) surface exhibits a robust surface spin polarization due to the internal charge transfer between atomic Ce and O layers. In turn, it can lower the surface oxygen vacancy formation energy and enhance the oxide reducibility. We show that the inclusion of spin polarization can therefore significantly reduce the major activation barrier in the proposed reaction pathway of CO oxidation on ceria-supported Pt nanoparticles. For metal-support interactions, surface spin polarization enhances the bonding between Pt nanoparticle and ceria surface oxygen, while CO adsorption on Pt nanoparticles weakens the interfacial interaction regardless of spin polarization.
description: 10 pages, 5 figures
Factors associated with healthcare avoidance among transgender women in Argentina
Creators: name: Socias, M. Eugenia
name: Marshall, Brandon David Lewis
name: Arístegui, Inés
name: Romero, Marcela
name: Cahn, Pedro
name: Kerr, Thomas
name: Sued, Omar
Publisher: name: BioMed Central
Year: 2015

description: Introduction: Transgender (TG) women in many settings continue to contend with barriers to healthcare, including experiences of stigma and discrimination. Argentina has a universal health care system and laws designed to promote healthcare access among TG women. However, little is known about barriers to healthcare access among TG women in this setting. The aim of this study was to explore individual, social-structural and environmental factors associated with healthcare avoidance among TG women in Argentina. Methods Data were derived from a 2013 nation-wide, cross-sectional study involving TG women in Argentina. We assessed the prevalence and factors associated with avoiding healthcare using multivariable logistic regression. Results Among 452 TG women included in the study, 184 (40.7%) reported that they avoided seeking healthcare because of their transgender identity. In multivariable analysis, factors positively associated with avoiding seeking healthcare were: having been exposed to police violence (adjusted odd ratio [aOR] = 2.20; 95% CI: 1.26 – 3.83), internalized stigma (aOR = 1.60, 95% CI: 1.02–2.51), having experienced discrimination by healthcare workers (aOR = 3.36: 95% CI: 1.25 – 5.70) or patients (aOR = 2.57; 95% CI: 1.58 – 4.17), and currently living in the Buenos Aires metropolitan area (aOR = 2.32; 95% CI: 1.44 – 3.76). In contrast, TG women with extended health insurance were less likely to report avoiding healthcare (aOR = 0.49; 95% CI: 0.26 – 0.93). Conclusions A high proportion of TG women in our sample reported avoiding healthcare. Avoiding healthcare was associated with stigma and discrimination in healthcare settings, as well as police violence experiences. Although further research is warranted, these finding suggests that socio-structural interventions tailored TG women needs are needed to improve access to healthcare among this population.
Finiteness of spinfoam vertex amplitude with timelike polyhedra, and the full amplitude
Creators: name: Han, Muxin
name: Kaminski, Wojciech
name: Liu, Hongguang
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: This work focuses on Conrady-Hnybida's 4-dimensional extended spinfoam model with timelike polyhedra, while we restrict all faces to be spacelike. Firstly, we prove the absolute convergence of the vertex amplitude with timelike polyhedra, when SU(1,1) boundary states are coherent states or the canonical basis, or their finite linear combinations. Secondly, based on the finite vertex amplitude and a proper prescription of the SU(1,1) intertwiner space, we construct the extended spinfoam amplitude on arbitrary cellular complex, taking into account the sum over SU(1,1) intertwiners of internal timelike polyhedra. We observe that the sum over SU(1,1) intertwiners is infinite for the internal timelike polyhedron that has at least 2 future-pointing and 2 past-pointing face-normals. In order to regularize the possible divergence from summing over SU(1,1) intertwiners, we develop a quantum cut-off scheme based on the eigenvalue of the ``shadow operator''. The spinfoam amplitude with timelike internal polyhedra (and spacelike faces) is finite, when 2 types of cut-offs are imposed: one is imposed on $j$ the eigenvalue of area operator, the other is imposed on the eigenvalue of shadow operator for every internal timelike polyhedron that has at least 2 future-pointing and 2 past-pointing face-normals.
description: 29 pages
Volumetric Additive Manufacturing of Silica Glass with Microscale Computed Axial Lithography
Creators: name: Toombs, Joseph
name: Luitz, Manuel
name: Cook, Caitlyn
name: Jenne, Sophie
name: Li, Chi Chung
name: Rapp, Bastian
name: Kotz-Helmer, Frederik
name: Taylor, Hayden
Publisher: name: arXiv
Year: 2021
Subjects: subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Glass is increasingly desired as a material for manufacturing complex microscopic geometries, from the micro-optics in compact consumer products to microfluidic systems for chemical synthesis and biological analyses. As the size, geometric, surface roughness, and mechanical strength requirements of glass evolve, conventional processing methods are challenged. We introduce microscale computed axial lithography (micro-CAL) of fused silica components, by tomographically illuminating a photopolymer-silica nanocomposite which is then sintered. We fabricated 3D microfluidics with internal diameters of 150 micrometers, freeform micro-optical elements with surface roughness of 6 nm, and complex high-strength trusses and lattice structures with minimum feature sizes of 50 micrometers. As a high-speed, layer-free digital light manufacturing process, micro-CAL can process extremely viscous nanocomposites with high geometric freedom, enabling new device structures and applications.
Gell-Mann-Low criticality in neural networks
Creators: name: Tiberi, Lorenzo
name: Stapmanns, Jonas
name: Kühn, Tobias
name: Luu, Thomas
name: Dahmen, David
name: Helias, Moritz
Publisher: name: arXiv
Year: 2021
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Criticality is deeply related to optimal computational capacity. The lack of a renormalized theory of critical brain dynamics, however, so far limits insights into this form of biological information processing to mean-field results. These methods neglect a key feature of critical systems: the interaction between degrees of freedom across all length scales, which allows for complex nonlinear computation. We present a renormalized theory of a prototypical neural field theory, the stochastic Wilson-Cowan equation. We compute the flow of couplings, which parameterize interactions on increasing length scales. Despite similarities with the Kardar-Parisi-Zhang model, the theory is of a Gell-Mann-Low type, the archetypal form of a renormalizable quantum field theory. Here, nonlinear couplings vanish, flowing towards the Gaussian fixed point, but logarithmically slowly, thus remaining effective on most scales. We show this critical structure of interactions to implement a desirable trade-off between linearity, optimal for information storage, and nonlinearity, required for computation.