cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The FAST Pump, a low-cost, easy to fabricate, SLA-3D-printed peristaltic pump for multi-channel systems in any lab
Creators: name: Jönsson, Alexander
name: Toppi, Arianna
name: Dufva, Martin
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Laboratory and Basic Science Research Life Sciences
subject: Mechanical Engineering
subject: FOS: Mechanical engineering
subject: Biomedical Devices and Instrumentation
subject: Engineering Education
subject: Life Sciences
subject: Other Mechanical Engineering
subject: Engineering
subject: Biomedical Engineering and Bioengineering
subject: Open source hardware, Open hardware, 3D-printing, Stereolithography, SLA, DLP, Off the shelf

description: This project supports the paper: Alexander Jönsson, Arianna Toppi and Martin Dufva. The FAST Pump, a low-cost, easy to fabricate, SLA-3D-printed peristaltic pump for multi-channel systems in any lab
Patients’ barriers and facilitators to manage their core health data in an electronic health record
Creators: name: Damen, Debby
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Health Information Technology
subject: Communication
subject: Medical Humanities
subject: Digital Humanities
subject: Medicine and Health Sciences
subject: Arts and Humanities
subject: Health Communication
subject: Social and Behavioral Sciences
subject: Health and Medical Administration
subject: electronic health record
subject: electronic medical record
subject: medical health record
subject: medical record
subject: patient empowerment
subject: patient generated health data
subject: patient participation
subject: patient portal
subject: personal electronic health record
subject: shared decision making
subject: web portal

description: The aim of this scoping review is to synthesize existing knowledge about the barriers and facilitators patients face when they (decide to) engage with a personal electronic health record (PEHR) to generate and manage their core health data.
Exploring the populations, interventions, settings, outcomes, and evidence for clinical supervision in cognitive behaviour therapy: A systematic review to guide future research on clinical supervision
Creators: name: Feliciano, Ivy
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: cbt
subject: cognitive behaviour therapy
subject: supervision

description: This registration is for a systematic review of clinical supervision in the context of Cognitive Behavioural Therapy.
High 5s Kindergarten Math Clubs Impact Analyses Third Grade Follow-Up
Creators: name: Mattera, Shira
name: Jacob, Robin
name: Morris, Pamela
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Education
subject: Early Childhood Education
subject: Elementary Education

description: The High 5s Program is part of the Robin Hood Early Childhood Research Initiative, a partnership between MDRC and the Robin Hood Foundation. The High 5s Program is an extension of Making PreK Count (MPC) and is intended to provide a continued emphasis on math skills for Kindergarten students who experienced Building Blocks (BB) in Pre-K through MPC. In the High 5s Program, groups of approximately four kindergarten students met three times a week with a trained Facilitator from Bank Street College of Education. Facilitators provided students with targeted instruction as they played fun, engaging math games. Previous research estimated the short term impacts of the High 5s program on students' Kindergarten outcomes. This analysis estimates the impacts on children’s third grade outcomes for the students who received BB-MPC and High 5s, compared with students who received BB-MPC and kindergarten-as-usual (a control group).
Formation of supermassive stars in the first star clusters
Creators: name: Reinoso, Bastián
name: Klessen, Ralf S.
name: Schleicher, Dominik
name: Glover, Simon C. O.
name: Solar, P.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The formation of supermassive stars is believed to be an essential intermediate step for the formation of the massive black hole seeds that become the supermassive black holes powering the quasars observed in the early Universe. Numerical simulations have shown that supermassive stars can form in atomic-cooling halos when protostars reach accretion rates higher than $\sim10^{-2}$ M$_\odot$ yr$^{-1}$ and fragmentation is suppressed on pc scales. It is however still uncertain if a supermassive star still emerges when fragmentation occurs at smaller scales and a cluster of stars is formed instead. In this work we explore the problem of massive object formation due to the interplay of collisions and accretion in star clusters at low metallicity. We model a small embedded cluster of accreting protostars following sub-parsec scale fragmentation during the collapse of a primordial gas cloud and follow its evolution by performing $N$-body plus hydrodynamical simulations. Our results show that supermassive stars with 10$^3$ and 10$^4$ M$_\odot$ are always formed due to the interplay of collisions and accretion, and in some cases these objects are part of a binary system. The resulting supermassive star is surrounded by tens of smaller stars with typical masses in the range $1$-$100$ M$_\odot$.
description: 16 pages, 20 figures, accepted by MNRAS
Do psychotherapists’ personality influence patients’ experience, process, and treatment outcomes?
Creators: name: Fletcher, Ashleigh
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Clinical Psychology
subject: Psychotherapist Personality
subject: Therapy Processes
subject: Treatment Outcomes

description: Scoping literature review exploring whether psychotherapists' personality influences patients' experience of therapy, therapy processes, and treatment outcomes.
Machine Learning Approaches in Agile Manufacturing with Recycled Materials for Sustainability
Creators: name: Varde, Aparna S.
name: Liang, Jianyu
Publisher: name: arXiv
Year: 2023
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: I.2.m; J.2

description: It is important to develop sustainable processes in materials science and manufacturing that are environmentally friendly. AI can play a significant role in decision support here as evident from our earlier research leading to tools developed using our proposed machine learning based approaches. Such tools served the purpose of computational estimation and expert systems. This research addresses environmental sustainability in materials science via decision support in agile manufacturing using recycled and reclaimed materials. It is a safe and responsible way to turn a specific waste stream to value-added products. We propose to use data-driven methods in AI by applying machine learning models for predictive analysis to guide decision support in manufacturing. This includes harnessing artificial neural networks to study parameters affecting heat treatment of materials and impacts on their properties; deep learning via advances such as convolutional neural networks to explore grain size detection; and other classifiers such as Random Forests to analyze phrase fraction detection. Results with all these methods seem promising to embark on further work, e.g. ANN yields accuracy around 90\% for predicting micro-structure development as per quench tempering, a heat treatment process. Future work entails several challenges: investigating various computer vision models (VGG, ResNet etc.) to find optimal accuracy, efficiency and robustness adequate for sustainable processes; creating domain-specific tools using machine learning for decision support in agile manufacturing; and assessing impacts on sustainability with metrics incorporating the appropriate use of recycled materials as well as the effectiveness of developed products. Our work makes impacts on green technology for smart manufacturing, and is motivated by related work in the highly interesting realm of AI for materials science.
title: Clinical and neuroimaging findings in glutaric aciduria type 1: A case study
Creators: name: Urtasun Iriarte, Cesar
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Paediatric radiology
subject: CNS
subject: Neuroradiology brain
subject: Paediatric
subject: MR
subject: Congenital
subject: Genetic defects
subject: Clinical Cases

description: Clinical History: A 7-month-old girl presented to the emergency room with tonic spasms following gastroenteritis. She was born to non-consanguineous parents and had a feeding history based on artificial formulas. Examination showed macrocephaly, hypotonia, and asymmetric dystonic posture. MRI was ordered. Urine analysis showed increased glutaric acid (>10000 mmol/mol; normal range 0.6 - 6.6) and 3- hidroxiglutaric (250 mmol/mol; normal range 0 - 5.69).

description: 7 months, female
Injuries and Circumstances Associated with Electric Scooter Accidents: Scoping Review Protocol
Creators: name: Toofany, Manish
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: accident
subject: collision
subject: electric scooter
subject: epidemiology
subject: e-scooter
subject: fall
subject: incident
subject: injuries
subject: injury
subject: mobility device
subject: review
subject: road safety
subject: scoping review
subject: trauma
subject: wounds and injuries

description: Pre-registration of scoping review protocol.
Radio and mid-infrared properties of the blazar J1419$-$0838
Creators: name: Perger, Krisztina
name: Frey, Sándor
name: Gabányi, Krisztina Éva
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The radio quasar NVSS J141922$-$083830 (J1419$-$0838) was initially classified as an uncategorised blazar-type object, following its detection in the $γ$-ray band with the Fermi space telescope. Later, using multi-waveband observations and modeling, its was found to be a flat-spectrum radio quasar (FSRQ). However, its radio emission has never been discussed in depth in the literature. Here we present a detailed analysis on the radio properties of J1419$-$0838 using archival interferometric imaging data at pc and kpc scales. We conclude that the flux density variations, the flat radio spectrum, the compact nature of the quasar structure at all scales, and the relativistic Doppler enhancement of the radio emission all support the previous classification as an FSRQ. We also investigated the short- and long-term mid-infrared (MIR) light curve of the quasar based on observations by the Wide-field Infrared Survey Explorer satellite, and found that there is significant variability on time-scales of days as well as years. Comparison of the MIR light curve to the times of previously reported $γ$-ray and optical flares shows no clear correlation between the events at different wavebands.
description: 15 pages, 5 figures, 3 tables, accepted for publication in Astrophysics and Space Science
Table S1: from Photoperiod-driven concurrent changes in hypothalamic and brainstem transcription of sleep and immune genes in migratory redheaded bunting
Creators: name: Tiwari, Jyoti
name: Sur, Sayantan
name: Yadav, Anupama
name: Kumar, Raj
name: Rai, Niraj
name: Rani, Sangeeta
name: Malik, Shalie
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Active and sleep behaviors in redheaded buntings
Stress, Psychoneurological Symptoms and Quality of Life During Protective Isolation Related to Hematapoetic Stem Cell Transplantation: Does Blogging Help?
Creators: name: Nance, Jennifer
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Background & Objective: Emerging adults (EA) have a unique set of needs as compared to older adults during protective isolation following a hematopoietic stem cell transplant (HSCT). EA, who are typically beginning to develop independence and establish their own lives, are now thrust by HSCT into a completely dependent situation that can create anxiety, uncertainty, and loneliness. This case study aims to describe the stress and psychological symptoms experienced by an EA during protective isolation following HSCT and to explore how blogging may be a strategy for coping with stress and improving quality of life during this time.
Materials & Methods: This study used an observational longitudinal design and ethnographic methods to analyze data from a publically available illness blog written by an EA and published online by the New York TimesTM.
Results: Stressors during isolation included uncertainty about illness trajectory, negative physical symptoms/treatment side effects, and social isolation. Coping strategies used were distraction, problem solving, and rejoining social media. The most effective coping strategy used, which improved throughout the blogger’s time in isolation, was the act of writing.
Conclusion: Studying illness blogs is a way to observe the course an illness takes and how patients respond to their individual treatment. At the same time, offering blogging, or expressive writing, as a coping strategy to those preparing to undergo HSCT is a potentially beneficial intervention to improve patient’s health related quality of life while in the hospital and after leaving.
Imaging effects due to pixel distortions in CdZnTe (CZT) detectors -- results from the HREXI Calibration Facility (HCF)
Creators: name: Basak, Arkadip
name: Allen, Branden
name: Hong, Jaesub
name: Violette, Daniel P.
name: Grindlay, Jonathan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: ProtoEXIST2 (P2) was a prototype imaging X-ray detector plane developed for wide-field Time Domain Astrophysics (TDA) in the 5 - 200 keV energy band. It was composed of an 8 $\times$ 8 array of 5 mm thick, 2cm $\times$ 2cm pixelated (32 $\times$ 32) CdZnTe (CZT) detectors with a 0.6 mm pitch that utilize the NuSTAR ASIC(NuASIC) for readout. During the initial detector development process leading up to post-flight examination of the entire detector plane, distortions in expected pixel positions and shapes were observed in a significant fraction of the detectors. The HREXI (High Resolution Energetic X-ray Imager) Calibration Facility (HCF) was designed and commissioned to improve upon these early experiments and to rapidly map out and characterize pixel non-uniformities and defects within CZT detector planes at resolutions down to 50 $\rm μ$m. Using this facility, the sub-pixel level detector response of P2 was measured at 100 $\rm μ$m resolution and analyzed to extract and evaluate the area and profile of individual pixels, their morphology across the entire P2 detector plane for comparison with previous measurements and to provide additional characterization. In this article, we evaluate the imaging performance of a coded-aperture telescope using the observed pixel morphology for P2 detectors. This investigation will serve as an initial guide for detector selection in the development of HREXI detector planes, for the future implementation of the 4pi X-Ray Imaging Observatory (4piXIO) mission which aims to provide simultaneous and continuous imaging of the full sky ($\rm 4π$ sr) in the 3-200 keV energy band with $\rm \simeq$ 2 arcmin angular resolution and $\simeq$ 10 arcsec source localization, as well as other, future coded-aperture instruments.
Semantics of templates in a compositional framework for building logics
Creators: name: Dasseville, Ingmar
name: van der Hallen, Matthias
name: Janssens, Gerda
name: Denecker, Marc
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: There is a growing need for abstractions in logic specification languages such as FO(.) and ASP. One technique to achieve these abstractions are templates (sometimes called macros). While the semantics of templates are virtually always described through a syntactical rewriting scheme, we present an alternative view on templates as second order definitions. To extend the existing definition construct of FO(.) to second order, we introduce a powerful compositional framework for defining logics by modular integration of logic constructs specified as pairs of one syntactical and one semantical inductive rule. We use the framework to build a logic of nested second order definitions suitable to express templates. We show that under suitable restrictions, the view of templates as macros is semantically correct and that adding them does not extend the descriptive complexity of the base logic, which is in line with results of existing approaches.
Tweeting with Emotion: News Organizations' Use of Affect on Twitter
Creators: name: Bellovary, Andrea
name: Young, Nathaniel
name: Quinn, Kimberly
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: affect
subject: decision making
subject: news organizations
subject: political orientation
subject: social media

description: This study is an expansion of a previously conducted exploratory pilot study (Bellovary, Young, & Quinn, 2019). We aim to examine how left- and right-leaning news organizations use affective messages on Twitter and how those messages lead to interactions with tweets.
Table S3: from Photoperiod-driven concurrent changes in hypothalamic and brainstem transcription of sleep and immune genes in migratory redheaded bunting
Creators: name: Tiwari, Jyoti
name: Sur, Sayantan
name: Yadav, Anupama
name: Kumar, Raj
name: Rai, Niraj
name: Rani, Sangeeta
name: Malik, Shalie
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Table of Statistics
Efficient Quantum Walk on a Quantum Processor
Creators: name: Qiang, Xiaogang
name: Loke, Thomas
name: Montanaro, Ashley
name: Aungskunsiri, Kanin
name: Zhou, Xiaoqi
name: O'Brien, Jeremy L.
name: Wang, Jingbo
name: Matthews, Jonathan C. F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The random walk formalism is used across a wide range of applications, from modelling share prices to predicting population genetics. Likewise quantum walks have shown much potential as a frame- work for developing new quantum algorithms. In this paper, we present explicit efficient quantum circuits for implementing continuous-time quantum walks on the circulant class of graphs. These circuits allow us to sample from the output probability distributions of quantum walks on circulant graphs efficiently. We also show that solving the same sampling problem for arbitrary circulant quantum circuits is intractable for a classical computer, assuming conjectures from computational complexity theory. This is a new link between continuous-time quantum walks and computational complexity theory and it indicates a family of tasks which could ultimately demonstrate quantum supremacy over classical computers. As a proof of principle we have experimentally implemented the proposed quantum circuit on an example circulant graph using a two-qubit photonics quantum processor.
description: 10 pages, 5 figures
Vitamin D3 Reduces Motor Neuron Death in a Model of ALS
Creators: name: Anderson, Cathy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which
progressive motor neuron degeneration causes paralysis and, ultimately, death. A subset of ALS
cases are caused by mutations in superoxide dismutase (SOD1). These mutations compromise
the structure of the protein, which cause it to misfold and aggregate. Protein aggregates including
SOD1 are found in inclusion bodies in spinal cord sections of both familial and sporadic ALS
patients. The role of these aggregates in disease pathogenesis is not well known, and the
mechanism of motor neuron death in ALS remains a mystery. However, glutamate-induced
excitotoxicity, which occurs when cells lose the ability to buffer intracellular calcium
concentrations and die from over-excitation, has been shown to have a significant role in ALS
motor neuron death. Healthy cells have efficient safety mechanisms to protect against
excitotoxicity. For example, vitamin D3 upregulates the expression of calcium-binding proteins,
which buffer rising intracellular calcium levels. Based on this, we hypothesize that vitamin D3
supplementation can protect from glutamate-induced excitotoxicity in an ALS cell culture model.
We treated motor neuron-like cells expressing an aggressive disease mutant, A4V SOD1, with
vitamin D3 and measured its effect on cell viability. We show that vitamin D3 restores viability in
cells expressing A4V SOD1 to that of cells expressing wild-type SOD1, suggesting that vitamin
D3 can protect from SOD1-mediated motor neuron cell death. This finding may lead to
implementation of vitamin D3 supplements as a complementary treatment method for ALS
patients and encourage further research to improve intracellular calcium-buffering in ALS.
Open Science no CTMM
Creators: name: Collodetti, Mélcar
name: Romano-Silva, Marco
name: Souza e Silva, Nathália
name: Nogueira Souza, Ana
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Ciência Aberta
subject: CTMM
subject: Marco Aurélio Romano-Silva
subject: Neuroscience
subject: Open Science

description: Esse projeto visa estabelecer formas de implementar o movimento de Ciência Aberta ao CTMM-UFMG
Serotonergic Regulation of Adult Neurogenesis in the Dentate Gyrus
Creators: name: Patel, Aashka
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Neurogenesis is the process through which adult neural stem cells (ANSCs) produce new neurons and glial cells. The number of neurons generated from neurogenesis can affect learning, memory, mood, and the onset of several mental illnesses. For example, the neurogenesis hypothesis of depression states that decreased neurogenesis increases an individual’s vulnerability to depression. Other factors, such as stress, precipitate many mental illnesses, as well as trigger a decrease in neurogenesis. Many neurotransmitters, such as serotonin, regulate neurogenesis; however, it is unclear exactly how serotonin inputs may be regulating the developmental stages of neurogenesis. We believe that the 5HT1a receptor (5ht1ar) is integral to serotonergic regulation of neurogenesis and hypothesize that administration of selective serotonin reuptake inhibitors (SSRIs) will increase rates of neurogenesis in a wild type model, but not in a conditional knockout model. Using in situ hybridization and gene trap reporter mice, we first confirmed the presence of 5htr1a in ANSC cells. In our pilot experiment, we administered fluoxetine (a commonly administered SSRI) to a cohort of male and female mice over a period of 2 weeks and observed an increase in stem cell proliferation. We then took a functional genetic approach of conditionally deleting Htr1a (the gene encoding for 5ht1ar) using CreER drivers specifically in ANSCs and immunohistochemistry to determine how stem cells react to loss of Htr1a. This experiment showed a difference in morphology and developmental stage of stem cell progenitors between the wild-type and conditional knockouts mice. The presence of the 5htr1a receptor shows a differential response in ANSCs to varying levels of serotonin. Our data provides evidence for a significant push towards stem cell differentiation and progenitor cell maturation when ANSCs expressed 5ht1ar and were in the presence of fluoxetine. Further knowledge on how serotonin and the 1a receptor modulate adult neurogenesis can help us have a better understanding of diseases, especially depression, that arise from serotonin deficiency.
Hormonal Contraception Use and Adverse Health Outcomes: An Umbrella Review Protocol
Creators: name: VEETTIL, SAJESH
name: Brabaharan, Sharmila
name: Chaiyakunapruk, Nathorn
name: Maharajan, Marikannan
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences

description: This is a protocol for an umbrella review (systematic evaluation of systematic reviews and meta-analyses) that will examine the associations between hormonal contraception (HCP) use and adverse health outcomes in many populations.
An Analysis of the Religious Rights and Freedoms Afforded to Undocumented Immigrants in the United States
Creators: name: Batchelor, Katharine
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The purpose of this study is to explore these views, realities, dichotomies, and
complexities through a geographical and legal lens. Broadly speaking, my research begins at an intersection of religion and immigration. In narrowing the focus, the aim of the research is to determine what, if any, religious rights and freedoms are enjoyed by undocumented immigrants after their arrival in the United States. As an extension, my study explores how the citizenship and identity of an immigrant as undocumented affects his/her expressions of religiosity. The study will focus on more traditional methods of practicing or expressing religion (worship service attendance, reception of counsel from religious leaders, etc.) and how undocumented immigrants are able to utilize those traditional methods in the United States. Tangentially, the ability of undocumented immigrants to banally express religious beliefs or habits may be indicative of the overall perceptions that United States society holds about immigrants. The study
will subsequently explore the relationship between the religious rights and freedoms of American citizens and undocumented immigrants. Lastly, this study also aims to learn about the notions Americans have regarding undocumented immigrants as people with complex identities, particularly notions about immigrants as religious persons.
Enzymatic Synthesis of UDP-Glucuronic Acid from Glucose
Creators: name: Woody, Susan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Heparin is a highly sulfated form of the polysaccharide heparan sulfate and is commonly used as an anticoagulant. As an animal sourced product, heparin is a heterogeneous product, containing polysaccharides that differ in length and sulfation pattems. After contamination of heparin with over-sulfated chondroitin sulfate in 2007, and in the interest of studying other potential pharmacological activities, there have been efforts to synthesize heparin in a cost­-effective manner. Specifically, chemoenzymatic synthesis is a leading method for efficient and inexpensive production of heparin.
One of the limitations in this process is the cost of purchasing the two starting sugar­nucleotides. Previously, our lab has developed methods to produce UDP-GlcNTF A (uridine diphosphate N-trifluoroacetylglucosamine) effectively, but there is still considerable expense in purchasing UDP-GlcA (uridine diphosphate-glucuronic acid).
Using previous reports of sugar-nucleotide chemoenzymatic synthesis on a large scale, the purpose of my research has been to develop and implement a method to enzymatically synthesize UDP-GlcA, an expensive starting reactant, from glucose, a more cost-effective starting material. Note that this is an extensive project and includes additional work for my graduate program. Therefore, this report reflects only a portion of my research, focusing in particular on some problem solving aspects of research that have been overcome during my time in the honors program.
Optimal experimental designs for fMRI via circulant biased weighing designs
Creators: name: Cheng, Ching-Shui
name: Kao, Ming-Hung
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise statistical inference on brain functions, but research on this topic is very lacking. We develop a general theory to guide the selection of fMRI designs for estimating a hemodynamic response function (HRF) that models the effect over time of the mental stimulus, and for studying the comparison of two HRFs. We provide a useful connection between fMRI designs and circulant biased weighing designs, establish the statistical optimality of some well-known fMRI designs and identify several new classes of fMRI designs. Construction methods of high-quality fMRI designs are also given.
description: Published at http://dx.doi.org/10.1214/15-AOS1352 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Regulation of Adult Neurogenesis by the Hippocampal Cholecystokinin Network
Creators: name: Lim, Szu-Aun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Adult neurogenesis is the process of generating functional neurons from neural stem cells (NSCs) in the adult brain. In humans, this unique form of neuroplasticity is restricted to the dentate gyrus (DG) of the hippocampus. Unlike developmental neurogenesis, adult neurogenesis is regulated by local and long distance neuronal circuit activity. However, the identities of specific cell types, neurotransmitters, and receptors that facilitate this regulation remain largely unknown. Studies utilizing animal and cell culture models suggest that the neuropeptide cholecystokinin (CCK) serves as a mitogenic signal for NSCs in the adult brain, but the direct effects of CCK have remained unclear.
GEFCOM 2014 - Probabilistic Electricity Price Forecasting
Creators: name: Barta, Gergo
name: Borbely, Gyula
name: Nagy, Gabor
name: Kazi, Sandor
name: Henk, Tamas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (stat.ML)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Machine Learning (cs.LG)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Energy price forecasting is a relevant yet hard task in the field of multi-step time series forecasting. In this paper we compare a well-known and established method, ARMA with exogenous variables with a relatively new technique Gradient Boosting Regression. The method was tested on data from Global Energy Forecasting Competition 2014 with a year long rolling window forecast. The results from the experiment reveal that a multi-model approach is significantly better performing in terms of error metrics. Gradient Boosting can deal with seasonality and auto-correlation out-of-the box and achieve lower rate of normalized mean absolute error on real-world data.
description: 10 pages, 5 figures, KES-IDT 2015 conference. The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-19857-6_7
Sparse Distributed Memory is a Continual Learner
Creators: name: Bricken, Trenton
name: Davies, Xander
name: Singh, Deepak
name: Krotov, Dmitry
name: Kreiman, Gabriel
Publisher: name: arXiv
Year: 2023
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Continual learning is a problem for artificial neural networks that their biological counterparts are adept at solving. Building on work using Sparse Distributed Memory (SDM) to connect a core neural circuit with the powerful Transformer model, we create a modified Multi-Layered Perceptron (MLP) that is a strong continual learner. We find that every component of our MLP variant translated from biology is necessary for continual learning. Our solution is also free from any memory replay or task information, and introduces novel methods to train sparse networks that may be broadly applicable.
description: 9 Pages. ICLR Acceptance
Using Ecological Momentary Assessment (EMA) to Study the Impact of Colored Glasses on Sleep Quality, Energy Level, and Mood
Creators: name: Freeman, Lindsey K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The connection between sleep disturbance and mood dysregulation is a current point of interest
in the field. The circadian rhythm system, which influences both sleep and mood, is itself
influenced by a variety of internal and external factors, one of which is light. Light manipulation
is a low-cost, non-invasive possibility for improving sleep and mood disturbances; blocking blue
wavelengths of light with amber-tinted glasses has been shown to improve sleep quality, energy
levels and mood. However, methods historically employed in studying sleep and mood are
limited in that assessments are generally given once per day, and may not give a complete
picture as to how well these interventions work. The present study used ecological momentary
assessment (EMA) to assess responsiveness to amber glasses (and blue lensed control glasses)
four times a day. Using a randomized crossover design, 38 participants at the University of North
Carolina at Chapel Hill were assigned to starting condition and wore colored glasses three hours
before bed for 12 of the 18 days of the study. Overall, the results did not support the hypothesis
that the amber glasses condition would improve sleep quality, energy, and mood: on some
outcome measures (sleep quality, energy level, positive affect), amber glasses steadily increased
sleep quality over the course of the condition, but this effect was also seen in the blue glasses
control condition. Future studies should include a washout period between conditions, a larger,
more diverse sample, more objective measures of sleep, and other colors of potential control
lenses.
Client Predictors of the Therapeutic Alliance in Individual Resiliency Training
Creators: name: Bass, Emily
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Individuals with first episode psychosis (FEP) are often reluctant to seek treatment,
resulting in difficulties with engagement and high dropout rates. The therapeutic alliance (TA),
the affective and collaborative bond between therapist and client, is predictive of better treatment
outcomes for clients with FEP; thus, it is valuable to study the predictors of the TA to elucidate
how best to foster a positive alliance with these individuals. The current study examined whether
baseline client characteristics including severity of symptoms, social functioning, duration of
untreated psychosis, and demographic factors (age, race), were associated with the TA. The
sample included clients who received Individual Resiliency Training (IRT) as part of the
NAVIGATE treatment in the NIMH Recovery After An Initial Schizophrenia Episode Early
Treatment Program study. Subjects (n=146) were assigned to a trained IRT therapist, and
sessions were audio recorded. Four undergraduate students were trained in using the Vanderbilt
Therapeutic Alliance Scale to rate the TA between client and therapist for audiotapes of session
3 of IRT. Multilevel modeling was utilized given the nested data structure. Results indicated a
significant positive relationship between positive symptoms and the TA, a significant negative
relationship between negative and excitative symptoms and the TA, and a significant positive
relationship between age and the TA. Results suggest that treatment providers working with FEP
clients should take into consideration the clients’ symptom severity and age when beginning
therapy, and adaptations to treatment should be made to foster a better TA in hopes of achieving
better engagement and treatment outcomes.
Lepton number asymmetry via inflaton decay in a modified radiative seesaw model
Creators: name: Kashiwase, Shoichi
name: Suematsu, Daijiro
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We propose a non-thermal scenario for the generation of baryon number asymmetry in a radiative neutrino mass model which is modified to realize inflation at the early Universe. In this scenario, inflaton plays a crucial role in both generation of neutrino masses and lepton number asymmetry. Lepton number asymmetry is firstly generated in the dark matter sector through direct decay of inflaton. It is transferred to the lepton sector via the dark matter annihilation and then converted to the baryon number asymmetry due to the sphaleron interaction. All of the neutrino masses, the baryon number asymmetry and the dark matter are intimately connected to each other through the inflaton.
description: 26 pages, 3 figures
EUTOPIA Citizen Science Starter Kit - Tool 17: Inclusiveness checklist
Creators: name: Veeckman, Carina
name: Van den Bogaert, Lawrence
name: Keersmaekers, Floor
name: Livémont, Eline
Publisher: name: Zenodo
Year: 2023
Subjects: citizen science
inclusion
inclusiveness

description: This template is part of Module 4 “Getting started with citizen science” (phase 2 – develop) of the EUTOPIA Citizen Science Starter Kit. It helps you to set up inclusive citizen science. The template is a checklist with good practices to reach underrepresented groups, or vulnerable and marginalized communities.
Energy estimates for the supersymmetric nonlinear sigma model and applications
Creators: name: Branding, Volker
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 53C27, 58E20, 35J61

description: We derive gradient and energy estimates for critical points of the full supersymmetric sigma model and discuss several applications.
The Political Economy of Ingenuity: Evaluating SME Entrepreneurship as Africa’s Silver Bullet for Economic Development
Creators: name: Muyanga, Amukelani
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: This research investigates how domestic SMEs’ business models are designed to help the poor navigate the circumstances of economic and social insecurity neoliberalism engenders, while also being proponents of the neoliberal project by capitalizing on the vacuum left by the state. This paper argues that SMEs play a contradictory role within South Africa’s neoliberal economic landscape given that they benefit from neoliberalism but also mitigate some of the economic insecurities it engenders for the poor segments that serve as clients, employees, or service providers.
SN 2011ht: Weak explosion in massive extended envelope
Creators: name: Chugai, N. N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: A possibility is explored to account for the light curve and the low expansion velocity of the supernova SN~2011ht, a member of group of three objects showing signatures of both IIn and IIP supernovae. It is argued that the radiated energy and the expansion velocity are consistent with the low energy explosion ($\approx6\times10^{49}$ erg) and $\leq 2 M_{\odot}$ ejecta interacting with the circumstellar envelope of $6-8 M_{\odot}$ and the radius of $~2\times10^{14}$ cm. The test of this scenario is proposed.
description: 11 pages, 3 figures, accepted by Astronomy Letters
Formulation and Analytic Essay
Creators: name: Ozies, Jaala
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420313
subject: Mental health services
classificationCode: 420318
subject: People with disability
classificationCode: 420311
subject: Health systems
classificationCode: 520299
subject: Biological psychology not elsewhere classified
classificationCode: 520401
subject: Cognition

description: This essay, written in June 2024 during my Master of Social Work Studies at the University of Queensland, presents a comprehensive case study on the formulation and analysis of a client with a mental health condition. It explores the application of theoretical frameworks and evidence-based practices to understand the client's challenges and develop effective intervention strategies.
Results of a search for neutrinoless double-beta decay using the COBRA demonstrator
Creators: name: Ebert, Joachim
name: Fritts, Matthew
name: Gehre, Daniel
name: Goessling, Claus
name: Hagner, Caren
name: Heidrich, Nadine
name: Klingenberg, Reiner
name: Kroeninger, Kevin
name: Nitsch, Christian
name: Oldorf, Christian
name: Quante, Thomas
name: Rajek, Silke
name: Rebber, Henning
name: Rohatsch, Katja
name: Tebruegge, Jan
name: Temminghoff, Robert
name: Theinert, Robert
name: Timm, Jan
name: Wonsak, Bjoern
name: Zatschler, Stefan
name: Zuber, Kai
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Neutrinoless double-$β$ decay ($0νββ$ decay) is a hypothetical process that can occur if the neutrino is its own antiparticle. The COBRA collaboration operates a demonstrator to search for these decays at the Laboratori Nazionali del Gran Sasso in Italy using CdZnTe semiconductor detectors. The exposure of $234.7\,$kg\,d considered in this analysis was collected between September 2011 and February 2015. The analysis focuses on the decay of the nuclides $^{114}$Cd, $^{128}$Te, $^{70}$Zn, $^{130}$Te and $^{116}$Cd. A Bayesian analysis is performed to estimate the signal strength of $0νββ$ decay. No signal is observed for any of these nuclides. Therefore, the following half-life limits at 90% credibility are set: $T_{1/2}^{0ν}>1.6\cdot10^{21}\,$yr ($^{114}$Cd), $T_{1/2}^{0ν}>1.9\cdot10^{21}\,$yr ($^{128}Te$), $T_{1/2}^{0ν}>6.8\cdot10^{18}\,$yr ($^{70}$Zn), $T_{1/2}^{0ν}>6.1\cdot10^{21}\,$yr ($^{130}$Te), and $T_{1/2}^{0ν}>1.1\cdot10^{21}\,$yr ($^{116}$Cd).
description: 7 pages, 8 figures and 3 tables, accepted by Phys. Rev. C
Reinmann theory + mathematical inventions
Creators: name: Yıldırım, Begüm
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 490499
subject: Pure mathematics not elsewhere classified

description: The Riemann Hypothesis (RH), one of the most significant unsolved problems in mathematics, posits that all non-trivial zeros of the Riemann zeta function lie on the critical line (R(s)=1/2). Despite numerous attempts, a universal proof remains elusive. This paper introduces Functional Series Symmetry (FSS) ,Weighted Derivatives and Functional Level Theory (FLT), which together provide a structured approach to understanding the behavior of zeros.The author acknowledges the use of OpenAI’s language model for assistance in drafting certain sections of this workl
3Rs search strategies for PubMed
Creators: name: Biggs, Patricia
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Model organisms
subject: Model organisms
classificationCode: Research Support
subject: Research Support

description: A series of search strategies requested by the Crick's head of BRF licencing and compliance. Strategies have been generated for common animal models used in life sciences and all aspects of 3Rs.

Search strategy has been designed to be modular to allow searchers to tailor searches to their own interests.
Evolution of Generalized Brans-Dicke parameter within a Superbounce scenario
Creators: name: Tripathy, S. K.
name: Pradhan, S. K.
name: Barik, B.
name: Naik, Z.
name: Mishra, B.
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We have studied a superbounce scenario in a set up of Brans-Dicke (BD) theory. The BD parameter is considered to be time dependent and is assumed to evolve with the Brans-Dicke scalar field. In the superbounce scenario, the model bounces at an epoch corresponding to a Big Crunch provided the ekpyrotic phase continues until that time. Within the given superbounce scenario, we investigate the evolution of the BD parameter for different equations of state. We chose an axially symmetric metric that has an axial symmetry along the x-axis. The metric is assumed to incorporate an anisotropic expansion effect. The effect of asymmetric expansion and the anisotropic parameter on the evolving and the non-evolving part of the BD parameter is investigated.
description: 10 pages, 5 figures, accepted version of the journal Symmetry
AFTERTHOUGHT
Creators: name: Kirkman, Katherine
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Contains following poems: For Zitkala-Sa; Peeling calluses; To my mother’s ex-lover; Little hurts; Caesura; Carolina; Known; Goldfish metaphor for relationships; Secrets; Short answer; Episodes; Like Calls to Like; Crystallization; Tell Me; Delineation; Sorry; Slough; Victimhooded; Super-ego; A Moral; Apostrophe for the Angel of Mercy; Consider this:; Reflection (Variation 2); Bed down; Slang; Taken; Consider; A Drink to Nature’s Course; Manifestation; In memorium; Levee-breaking; Prediction; Overture; And you tell me I’m petty; ___________; Remedy; Impermanence; Taking Care; To Sleep; Chasing El Dorado; Strung out; Legacy; Derived; Reflection (Variation 1)
Majoranas in Noisy Kitaev Wires
Creators: name: Hu, Ying
name: Cai, Zi
name: Baranov, Mikhail A.
name: Zoller, Peter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Robustness of edge states and non-Abelian excitations of topological states of matter promises quantum memory and quantum processing, which is naturally immune against microscopic imperfections such as static disorder. However, topological properties will not in general protect quantum system from time-dependent disorder or noise. Here we take the example of a network of Kitaev wires with Majorana edge modes storing qubits to investigate the effects of classical noise in the crossover from the quasi-static to the fast fluctuation regime. We present detailed results for the Majorana edge correlations, and fidelity of braiding operations for both global and local noise sources preserving parity symmetry, such as random chemical potentials and phase fluctuations. While in general noise will induce heating and dephasing, we identify examples of long-lived quantum correlations in presence of fast noise due to motional narrowing, where external noise drives the system rapidly between the topological and non-topological phases.