cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Search for physics beyond the standard model in dilepton mass spectra in proton-proton collisions at sqrt(s) = 8 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Dimuon and dielectron mass spectra, obtained from data resulting from proton-proton collisions at 8 TeV and recorded by the CMS experiment, are used to search for both narrow resonances and broad deviations from standard model predictions. The data correspond to an integrated luminosity of 20.6 (19.7) inverse femtobarns for the dimuon (dielectron) channel. No evidence for non-standard-model physics is observed and 95% confidence level limits are set on parameters from a number of new physics models. The narrow resonance analyses exclude a Sequential Standard Model Z'[SSM] resonance lighter than 2.90 TeV, a superstring-inspired Z'[psi] lighter than 2.57 TeV, and Randall-Sundrum Kaluza-Klein gravitons with masses below 2.73, 2.35, and 1.27 TeV for couplings of 0.10, 0.05, and 0.01, respectively. A notable feature is that the limits have been calculated in a model-independent way to enable straightforward reinterpretation in any model predicting a resonance structure. The observed events are also interpreted within the framework of two non-resonant analyses: one based on a large extra dimensions model and one based on a quark and lepton compositeness model with a left-left isoscalar contact interaction. Lower limits are established on M[S], the scale characterizing the onset of quantum gravity, which range from 4.9 to 3.3 TeV, where the number of additional spatial dimensions varies from 3 to 7. Similarly, lower limits on Lambda, the energy scale parameter for the contact interaction, are found to be 12.0 (15.2) TeV for destructive (constructive) interference in the dimuon channel and 13.5 (18.3) TeV in the dielectron channel.
description: Replaced with published version. Added journal reference and DOI
Earth Science and Democracy_The Role of Earth Science Information in Public Comments for Environmental Regulations.docx
Creators: name: Paz, Alejandro
Publisher: name: ESIP
Year: 2023
Subjects: classificationCode: 370102
subject: Air pollution processes and air quality measurement
classificationCode: 480408
subject: Law, science and technology

description: This document was the main working platform used by participants during the "Earth Science and Democracy: The Role of Earth Science Information in Public Comments for Environmental Regulations" presentation.
Авторитарные тенденции в Турции и радикализация правящей Партии справедливости и развития
Creators: name: Мирильяс Азад Оглы Агаев
Publisher: name: Антиномии
Year: 2020
Subjects: выборы
демократия
политический режим
популизм
Партия справедливости и развития
Турция
Эрдоган

description: Статья посвящена такому фактору становления авторитарных тенденций в Турции, как радикализация правящей Партии справедливости и развития. Автор, ссылаясь на концепции «демократического отступления» и «третьей волны демократического отката», рассматривает изменения, привнесенные в функционирование правящей партии, в качестве одной из основных причин смены методов государственного управления турецкой элитой. Выделяя два этапа в развитии политического режима Р.Т. Эрдогана: 2002–2011 гг. – демократизация и 2011 г. – н.в. – авторитарный поворот, он делает акцент на объяснении особенностей политического курса данных этапов с точки зрения изменения структуры и трансформации дискурса правящей партии и приходит к выводу о том, что изменение таких свойств политической стратегии, как коалиционность, популистская ориентация, опора на реформы и принципы либеральной демократии, умеренный характер политического стиля, привело к радикализации Партии справедливости и развития. Радикализация проявилась в антизападном внешнеполитическом курсе Турецкой Республики, преобладании негативной политической риторики по отношению к оппонентам и деактивизации принципа сдержек и противовесов в пользу расширения полномочий и роли исполнительной власти в лице Президента Турции Р.Т. Эрдогана. Немаловажным фактором является воздействие «внешних шоков» на политическую систему, к которым следует отнести рост протестных настроений, коррупционные скандалы, связанные с политическим окружением Р.Т. Эрдогана, усиление влияния оппозиционных партий на систему, использующих любую возможность ограничения власти Р.Т. Эрдогана вплоть до организации попытки военного переворота. Ввиду сложившейся политической ситуации для предотвращения падения рейтинга Партии справедливости и развития вносились коррективы в ее деятельность. Автор указывает, что в дальнейшем они способствовали созданию условий для авторитарного поворота, делая особый акцент на популистские стратегии.
Additional file 1 of Association between removable prosthesis-wearing and pneumonia: a systematic review and meta-analysis
Creators: name: Lim, Tong Wah
name: Li, Kar Yan
name: Burrow, Michael Francis
name: McGrath, Colman
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Местное самоуправление в правовых позициях Конституционного Суда РФ и его судей в контексте конституционной реформы-2020
Creators: name: Болдырев Олег Юрьевич
name: Чихладзе Леван Теймуразович
Publisher: name: Антиномии
Year: 2020
Subjects: Конституция РФ
Закон о поправке к Конституции
местное самоуправление
правовые позиции Конституционного Суда
особые мнения судей Конституционного Суда
территориально-поселенческий принцип
формирование органов местного самоуправления

description: Конституция РФ 1993 года заложила новые тенденции развития местного самоуправления. Важную роль в защите конституционного права на осуществление местного самоуправления призван играть Конституционный Суд Российской Федерации. Именно Конституционным Судом РФ сформировано само понятие местного самоуправления, в частности дано определение объема его прав и гарантий, а решения Конституционного Суда сыграли значительную роль в создании и трансформации российской модели местного самоуправления. В статье рассматриваются отдельные правовые позиции Конституционного Суда РФ, которые базировались на нормах Конституции РФ до внесения поправок, предусмотренных Законом о поправке к Конституции Российской Федерации от 14.03.2020 № 1-ФКЗ «О совершенствовании регулирования отдельных вопросов организации и функционирования публичной власти». Показано, что решения по многим делам, которые рассматривались Конституционным Судом и затрагивали различные аспекты проблематики местного самоуправления, вызывали дискуссию среди судей, что отражено в ряде мнений и особых мнений. В Заключении от 16.03.2020 № 1-З Конституционный Суд пришел к выводу о соответствии положениям глав 1, 2 и 9 Конституции РФ не вступивших на тот момент в силу положений Закона о поправке к Конституции, однако в статье показано, что они свидетельствуют о конституционном закреплении продолжающейся на протяжении ряда лет тенденции снижения выборности органов и должностных лиц местного самоуправления, а также о все большей централизации не только государственной, но и всей системы публичной власти в России. И хотя некоторые изменения, вносимые Законом о поправке к Конституции РФ, по сути, повторяют или развивают ранее сформулированные Конституционным Судом позиции, например о том, что «органы местного самоуправления и органы государственной власти входят в единую систему публичной власти в Российской Федерации…», другие изменения выхолащивают ранее сформулированные Конституционным Судом РФ правовые позиции о недопустимости передачи органам государственной власти полномочий, которые должны осуществляться только органами местного самоуправления либо населением муниципального образования непосредственно, или об особой роли поселений, «как таковых предназначенных для решения вопросов местного значения…», и мн. др. Соответственно, в связи с принятием Закона о поправке к Конституции РФ конституционные основы российской модели местного самоуправления подвергнутся значительным изменениям, и пока можно только прогнозировать, как это повлияет на правовые позиции Конституционного Суда РФ.
Midlife body mass index, central adiposity and neuropsychological performance over 10 years in women living with and without HIV
Creators: name: Mack W.J.
name: Fox E.
name: Appleton A.A.
name: Adimora A.A.
name: Plankey M.W.
name: Tien P.C.
name: Vásquez E.
name: Holman S.
name: Gustafson D.R.
name: Sharma A.
name: Rubin L.H.
name: Fischl M.A.
name: Moran C.A.
name: Weber K.M.
name: Kuniholm M.H.
name: Minkoff H.
Publisher: name: Frontiers Media SA
Year: 2023

description: Background and objective: Observations of overweight and obesity in association with neuropsychological performance (NP) vary over the adult life course depending on baseline levels, biological sex, age, race, temporality of measurements, and other factors. Therefore, similar published analyses across cohorts are inconsistent. In our sample of women living with HIV (WLWH) and women without HIV (WWOH), we conducted comparable analyses as those published in men with and without HIV. We examined cross-sectional and longitudinal associations between body mass index (BMI) and waist circumference (WC) and NP. Methods: Four hundred thirty two 432 virologically-suppressed WLWH and 367 WWOH, ≥40 years in the Women’s Interagency HIV Study (WIHS) with anthropometry and NP assessments every two years from 2009-2019 were included in the study. Demographically-adjusted T-scores were calculated for six NP domains: learning, memory, executive function, processing speed, attention and working memory, and motor function. Multivariable linear regression models stratified by HIV status were used to examine cross-sectional associations of BMI and WC by NP domain; repeated measures analyses assessed baseline BMI and WC in association with longitudinal change in NP. Covariates included sociodemographic, behavioral, and HIV-related characteristics. Results: At baseline among all women, the median age was 45 years, 65% were Non-Latinx Black women, and 45% were obese women. Obese WLWH (BMI≥30.0 kg/m2) had poorer executive function (β=-2.27, 95%CI [-4.46, -0.07]) versus WLWH with healthy BMI (18.5–24.9 kg/m2). Longitudinally over ~8 years, obese versus overweight WWOH improved on memory (β=2.19, 95%CI [0.13, 4.26]), however overweight versus healthy WWOH experienced declining memory (β= -2.67, 95%CI [-5.40, -0.07]). Increasing WC was associated with declining executive, processing speed, and motor function (p’s<0.05); an at-risk WC was associated with improved memory (β=1.81, 95%CI [0.19, 3.44]) among WWOH. Among WLWH, increasing BMI was associated with improved learning (β=0.07, 95%CI [0.00, 0.15]. Conclusion: Our cross-sectional and longitudinal analyses evaluating the associations of BMI and WC and NP were mixed compared to previous reports. This illustrates the importance of sociodemographic characteristics, baseline levels of exposures and outcomes, HIV status, temporality of measurements, and other factors when evaluating aging HIV epidemiology study results.
Activity02_Reflection.pdf
Creators: name: Paz, Alejandro
Publisher: name: ESIP
Year: 2023
Subjects: classificationCode: 370102
subject: Air pollution processes and air quality measurement
classificationCode: 480408
subject: Law, science and technology

description: A Google Jamboard from the "Earth Science and Democracy: The Role of Earth Science Information in Public Comments for Environmental Regulations" presentation. This Jamboard was part of a reflection activity.
The general structure of quantum resource theories
Creators: name: Brandão, Fernando G. S. L.
name: Gour, Gilad
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In recent years it was recognized that properties of physical systems such as entanglement, athermality, and asymmetry, can be viewed as resources for important tasks in quantum information, thermodynamics, and other areas of physics. This recognition followed by the development of specific quantum resource theories (QRTs), such as entanglement theory, determining how quantum states that cannot be prepared under certain restrictions may be manipulated and used to circumvent the restrictions. Here we discuss the general structure of QRTs, and show that under a few assumptions (such as convexity of the set of free states), a QRT is asymptotically reversible if its set of allowed operations is maximal; that is, if the allowed operations are the set of all operations that do not generate (asymptotically) a resource. In this case, the asymptotic conversion rate is given in terms of the regularized relative entropy of a resource which is the unique measure/quantifier of the resource in the asymptotic limit of many copies of the state. This measure also equals the smoothed version of the logarithmic robustness of the resource.
description: 5 pages, no figures, few references added, published version
Additional file 1 of Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma
Creators: name: Hsieh, Chih-Hsiung
name: Ho, Pei-Shiuan
name: Wang, Wen-Lun
name: Shih, Fu-Hsuan
name: Hong, Chen-Tai
name: Wang, Pei-Wen
name: Shieh, Dar-Bin
name: Chang, Wei-Lun
name: Wang, Yi-Ching
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary file 1.
Критерии отграничения новой диссертации от прежней работы, право защиты которой соискатель утратил (вариант нормативного закрепления)
Creators: name: Кокотова Дарья Александровна
Publisher: name: Антиномии
Year: 2020
Subjects: новая диссертация
прежняя диссертация
критерии отграничения
запрет повторной защиты диссертации
самоплагиат

description: Статья посвящена восполнению пробела, заключающегося в следующем. Соискатель лишается права повторной защиты диссертации за нарушение п. 14 «Положения о присуждении ученых степеней» и (или) представление недостоверных сведений о публикациях, даже если такая диссертация будет переработана. Однако отсутствуют критерии, руководствуясь которыми можно было бы отличить новую диссертацию от прежней (пускай и переделанной) диссертации, право защиты которой утрачено. Для определения возможного круга таких критериев автором изучены параметры, используемые (предлагаемые к использованию) для определения факта множественного опубликования одних и тех же статей в научных изданиях (в частности, рассматривались требования к публикациям на сайтах научных журналов, практика отзыва научных публикаций, экспертизы, представленные «Диссернет»). По мнению автора, целесообразно использовать следующие критерии: 1) доля совпадений с прежней диссертацией в общем объеме текста; 2) доля самостоятельного (не заимствованного) текста во фрагментах, не совпадающих с прежней диссертацией; 3) структурная часть, в которой содержатся совпадения; здесь речь прежде всего идет о заключении, положениях, выносимых на защиту, о пункте, посвященном новизне; помимо этого они могут иметь место в автореферате диссертации, в работах в рецензируемых научных изданиях, где опубликованы основные научные результаты диссертации; 4) соотношение структуры двух диссертаций; 5) наличие новой эмпирической базы; 6) наличие научной новизны по сравнению с прежней диссертацией. Отмечается, что могут быть использованы и другие критерии отграничения. Предлагается варьировать состав подлежащих применению критериев в зависимости от стадии рассмотрения диссертации и специфики задач, которые обычно ставятся перед участником такого процесса, решающего вопрос о том, может ли быть признан представленный текст новой диссертацией. Также в статье по итогам обсуждения того, каким может быть нормативное закрепления критериев, представлен вариант изменения актов, регулирующих требования к диссертациям и порядок защиты диссертаций.
Amoeba Techniques for Shape and Texture Analysis
Creators: name: Welk, Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences
subject: I.4.3; I.4.6; I.2.10; G.1.8; G.2.2

description: Morphological amoebas are image-adaptive structuring elements for morphological and other local image filters introduced by Lerallut et al. Their construction is based on combining spatial distance with contrast information into an image-dependent metric. Amoeba filters show interesting parallels to image filtering methods based on partial differential equations (PDEs), which can be confirmed by asymptotic equivalence results. In computing amoebas, graph structures are generated that hold information about local image texture. This paper reviews and summarises the work of the author and his coauthors on morphological amoebas, particularly their relations to PDE filters and texture analysis. It presents some extensions and points out directions for future investigation on the subject.
description: 38 pages, 19 figures v2: minor corrections and rephrasing, Section 5 (pre-smoothing) extended
Dialog mit Gott und Menschen
Creators: name: Neundorfer, Hannjürg
name: Prüller-Jagenteufel, Gunter M.
name: Erharter, Helmut
Publisher: name: Diakonia
Year: 1970

description: Diakonia, Bd. 31 Nr. 1 (2000): Diakonia, Band 31, Heft 1
Graph Neural Network for Object Reconstruction in Liquid Argon Time Projection Chambers
Creators: name: Hewes, V
name: Aurisano, Adam
name: Cerati, Giuseppe
name: Kowalkowski, Jim
name: Lee, Claire
name: Liao, Wei-keng
name: Day, Alexandra
name: Agrawal, Ankit
name: Spiropulu, Maria
name: Vlimant, Jean-Roch
name: Gray, Lindsey
name: Klijnsma, Thomas
name: Calafiura, Paolo
name: Conlon, Sean
name: Farrell, Steve
name: Ju, Xiangyang
name: Murnane, Daniel
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: This paper presents a graph neural network (GNN) technique for low-level reconstruction of neutrino interactions in a Liquid Argon Time Projection Chamber (LArTPC). GNNs are still a relatively novel technique, and have shown great promise for similar reconstruction tasks in the LHC. In this paper, a multihead attention message passing network is used to classify the relationship between detector hits by labelling graph edges, determining whether hits were produced by the same underlying particle, and if so, the particle type. The trained model is 84% accurate overall, and performs best on the EM shower and muon track classes. The model's strengths and weaknesses are discussed, and plans for developing this technique further are summarised.
description: 7 pages, 3 figures, submitted to the 25th International Conference on Computing in High-Energy and Nuclear Physics
Additional file 1 of Exploring the perspectives of health care professionals on digital health technologies in pediatric care and rehabilitation
Creators: name: Roy, Isabelle
name: Salles, Julia
name: Neveu, Erika
name: Lariviére-Bastien, Danaë
name: Blondin, Aurélie
name: Levac, Danielle
name: Beauchamp, Miriam H.
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1: Appendix 1: Survey questions
NeuroBridge ontology: computable provenance metadata to give the long tail of neuroimaging data a FAIR chance for secondary use
Creators: name: Ambite, Jose Luis
name: Wang, Yue
name: Appaji, Abhishek
name: Turner, Matthew D.
name: Turner, Jessica A.
name: Sahoo, Satya S.
name: Wang, Lei
name: Lander, Howard M.
name: Rajasekar, Arcot
Publisher: name: Frontiers Media SA
Year: 2023

description: Background Despite the efforts of the neuroscience community, there are many published neuroimaging studies with data that are still not findable or accessible. Users face significant challenges in reusing neuroimaging data due to the lack of provenance metadata, such as experimental protocols, study instruments, and details about the study participants, which is also required for interoperability. To implement the FAIR guidelines for neuroimaging data, we have developed an iterative ontology engineering process and used it to create the NeuroBridge ontology. The NeuroBridge ontology is a computable model of provenance terms to implement FAIR principles and together with an international effort to annotate full text articles with ontology terms, the ontology enables users to locate relevant neuroimaging datasets. Methods Building on our previous work in metadata modeling, and in concert with an initial annotation of a representative corpus, we modeled diagnosis terms (e.g., schizophrenia, alcohol usage disorder), magnetic resonance imaging (MRI) scan types (T1-weighted, task-based, etc.), clinical symptom assessments (PANSS, AUDIT), and a variety of other assessments. We used the feedback of the annotation team to identify missing metadata terms, which were added to the NeuroBridge ontology, and we restructured the ontology to support both the final annotation of the corpus of neuroimaging articles by a second, independent set of annotators, as well as the functionalities of the NeuroBridge search portal for neuroimaging datasets. Results The NeuroBridge ontology consists of 660 classes with 49 properties with 3,200 axioms. The ontology includes mappings to existing ontologies, enabling the NeuroBridge ontology to be interoperable with other domain specific terminological systems. Using the ontology, we annotated 186 neuroimaging full-text articles describing the participant types, scanning, clinical and cognitive assessments. ConclusionThe NeuroBridge ontology is the first computable metadata model that represents the types of data available in recent neuroimaging studies in schizophrenia and substance use disorders research; it can be extended to include more granular terms as needed. This metadata ontology is expected to form the computational foundation to help both investigators to make their data FAIR compliant and support users to conduct reproducible neuroimaging research.
Theory of anharmonic phonons in 2D crystals
Creators: name: Michel, K. H.
name: Costamagna, S.
name: Peeters, F. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Anharmonic effects in an atomic monolayer thin crystal with honeycomb lattice structure are investigated by analytical and numerical lattice dynamical methods. Starting from a semi-empirical model for anharmonic couplings of third and fourth order, we study the in-plane and out-of-plane (flexural) mode components of the generalized wave vector dependent Grüneisen parameters, the thermal tension and the thermal expansion coefficients as function of temperature and crystal size. From the resonances of the displacement-displacement correlation functions we obtain the renormalization and decay rate of in-plane and flexural phonons as function of temperature, wave vector and crystal size in the classical and in the quantum regime. Quantitative results are presented for graphene. There we find that the transition temperature from negative to positive thermal expansion is lowered with smaller system size and by renormalization of the flexural mode frequency. Extensive numerical analysis throughout the Brillouin zone explores various decay and scattering channels. The relative importance of Normal and Umklapp processes is investigated. The work is complementary to crystalline membrane theory and computational studies of anharmonic effects in two-dimensional crystals.
description: 24 pages, 18 figures
Stability of holomorphically-parallelizable manifolds
Creators: name: Angella, Daniele
name: Tomassini, Adriano
Publisher: name: arXiv
Year: 2014
Subjects: subject: Complex Variables (math.CV)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 32M10, 32G05, 53C30

description: We prove a stability theorem for families of holomorphically-parallelizable manifolds in the category of Hermitian manifolds.
Earth Science and Democracy: The Role of Earth Science Information in Public Comments for Environmental Regulations: ESIP Session Workflow
Creators: name: Paz, Alejandro
Publisher: name: ESIP
Year: 2023
Subjects: classificationCode: 480408
subject: Law, science and technology
classificationCode: 370102
subject: Air pollution processes and air quality measurement

description: This document contains an activity from the "Earth Science and Democracy: The Role of Earth Science Information in Public Comments for Environmental Regulations" presentation. Participants followed a workflow for identifying informational resources and data that could inform people writing and submitting public comments to an air quality standards proposed rule.
Magneto-elastic universal logic gate: A non-volatile, error-resilient Boolean logic gate with ultra-low energy-delay product
Creators: name: Biswas, Ayan K.
name: Atulasimha, Jayasimha
name: Bandyopadhyay, Supriyo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A long-standing goal of computer technology is to process and store digital information with the same device in order to implement new architectures. One way to accomplish this is to use nanomagnetic `non-volatile' logic gates that can perform Boolean operations and then store the output data in the magnetization states of nanomagnets, thereby doubling as both logic and memory. Unfortunately, many proposed nanomagnetic gates do not possess the seven essential characteristics of a Boolean logic gate: concatenability, non-linearity, isolation between input and output, gain, universal logic implementation, scalability and error resilience. More importantly, their energy-delay products and error-rates vastly exceed that of conventional transistor-based logic gates, which is a drawback. Here, we propose a non-volatile voltage-controlled nanomagnetic logic gate that possesses all the necessary characteristics of a logic gate and whose energy-delay product is ~2 orders of magnitude less than that of other nano-magnetic (non-volatile) logic gates and ~1 order of magnitude less than that of (volatile) CMOS-based logic gates. The error-resilience is also superior to that of other known nanomagnetic gates.
description: There were some typographical errors in version 2 which have been corrected
Mucolytic treatment of chronic rhinosinusitis in a murine model of primary ciliary dyskinesia
Creators: name: Yin, Weining
name: Golliher, Hannah L.
name: Livraghi-Butrico, Alessandra
name: Ferguson, Amy J.
name: Grubb, Barbara R.
name: Kimple, Adam J.
name: Ostrowski, Lawrence E.
name: Rogers, Troy D.
name: Kimbell, Julia S.
Publisher: name: Frontiers Media SA
Year: 2023

description: Background: Genetic defects in motile cilia cause primary ciliary dyskinesia (PCD), a rare disease with no specific therapeutics. Individuals with PCD often have impaired fertility and laterality defects and universally suffer from upper and lower airway diseases. Chronic rhinosinusitis is a universal feature of PCD, and mucus accumulation and subsequent infections of the sinonasal cavity cause significant morbidity in individuals with PCD. Despite this, there are no approved treatments that specifically target mucus.Objective: The goals of this study were to determine whether computed tomography (CT) imaging could be used to quantify mucus accumulation and whether the use of a mucolytic agent to reduce disulfide cross-links present in mucins would improve the effectiveness of nasal lavage at removing mucus in a murine model of PCD.Methods: Adult mice with a deletion of the axonemal dynein Dnaic1 were imaged using CT scanning to characterize mucus accumulation. The animals were then treated by nasal lavage with saline, with/without the disulfide-reducing agent tris(2-carboxyethyl)phosphine. Post-treatment CT scans were used to quantify improvement in the sinonasal cavity.Results: Mucus accumulation in the nasal cavity was readily quantified by CT. Compared to sham-treated control animals, nasal lavage with/without a mucolytic agent resulted in a significant reduction of accumulated mucus (p < 0.01). Treatment with the mucolytic agent showed a greater reduction of accumulated mucus than treatment with saline alone.Conclusion: The results suggest that inclusion of a mucolytic agent may increase the effectiveness of nasal lavage at reducing mucus burden in PCD.
Performance of a Geometric Deep Learning Pipeline for HL-LHC Particle Tracking
Creators: name: Ju, Xiangyang
name: Murnane, Daniel
name: Calafiura, Paolo
name: Choma, Nicholas
name: Conlon, Sean
name: Farrell, Steve
name: Xu, Yaoyuan
name: Spiropulu, Maria
name: Vlimant, Jean-Roch
name: Aurisano, Adam
name: Hewes, V
name: Cerati, Giuseppe
name: Gray, Lindsey
name: Klijnsma, Thomas
name: Kowalkowski, Jim
name: Atkinson, Markus
name: Neubauer, Mark
name: DeZoort, Gage
name: Thais, Savannah
name: Chauhan, Aditi
name: Schuy, Alex
name: Hsu, Shih-Chieh
name: Ballow, Alex
name: Lazar, and Alina
Publisher: name: arXiv
Year: 2021
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Machine Learning (cs.LG)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The Exa.TrkX project has applied geometric learning concepts such as metric learning and graph neural networks to HEP particle tracking. Exa.TrkX's tracking pipeline groups detector measurements to form track candidates and filters them. The pipeline, originally developed using the TrackML dataset (a simulation of an LHC-inspired tracking detector), has been demonstrated on other detectors, including DUNE Liquid Argon TPC and CMS High-Granularity Calorimeter. This paper documents new developments needed to study the physics and computing performance of the Exa.TrkX pipeline on the full TrackML dataset, a first step towards validating the pipeline using ATLAS and CMS data. The pipeline achieves tracking efficiency and purity similar to production tracking algorithms. Crucially for future HEP applications, the pipeline benefits significantly from GPU acceleration, and its computational requirements scale close to linearly with the number of particles in the event.
Concepts from Experience
Creators: name: F. William Lawvere
Publisher: name: Zenodo
Year: 2013
Subjects: Particular
General
Concept
Experience
Naturality
Algebra
Geometry
Foundations
Functorial Semantics

description: The extraction of abstract generals--by naturality--from particular families bears a profound resemblance to the basic extraction of concepts from experience.
description: What are Foundations of Geometry and Algebra? https://www.math.union.edu/~niefiels/13conference/Web/Abstracts/Lawvere.pdf
Decarbonisation of Primary Steel production by Deep Electrification
Creators: name: , Lavelaine
Publisher: name: Zenodo
Year: 2020
Subjects: Steel, Process, Carbon Neutrality, Climate Change

description: The steel industry generates between 7 and 9% of direct emissions from the global use of fossil fuel. It operates highly efficient processes and is considered difficult to decarbonize. However, the competitive deployment of renewable electricity might provide an opportunity for the decarbonisation of a portion of industry, through the direct use of electricity. Deep electrification of iron production could provide a contribution to the abatement of the overall GHG emissions. To these regards, H2020-ΣIDERWIN project proposes to develop a breakthrough innovation compared to the actual steel production process bringing together steel making with electrochemical process. By assuming that no genuine environmental improvement is possible without significant reduction of the amount of energy exchanged, the electrolytic process is designed and engineered to follow the thermodynamic route of least energy involvement between iron oxide and iron metal. This process has been gradually up scaled from workbench experiments at TechnicalReadinessLevel1 to laboratory pilot at TRL4 during the ULCOS project (2004-2010) and later projects such as RFCS-IERO, ANR-ASCoPE and ADEME-VALORCO. It is based on the electrowinning of iron in alkaline solution at 110°C. Now in the ΣIDERWIN project, a pilot of TRL6 is built to address the development of the key components of the technology and to operate in a relevant environment. The anticipated conditions to access to cheap iron oxide and electricity call to reinforce the ability of the process to treat non-ferrous metallurgy residues and to operate flexibly.
Quantum Transitions Between Classical Histories: Bouncing Cosmologies
Creators: name: Hartle, James
name: Hertog, Thomas
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In a quantum theory of gravity spacetime behaves classically when quantum probabilities are high for histories of geometry and field that are correlated in time by the Einstein equation. Probabilities follow from the quantum state. This quantum perspective on classicality has important implications: (a) Classical histories are generally available only in limited patches of the configuration space on which the state lives. (b) In a given patch states generally predict relative probabilities for an ensemble of possible classical histories. (c) In between patches classical predictability breaks down and is replaced by quantum evolution connecting classical histories in different patches. (d) Classical predictability can break down on scales well below the Planck scale, and with no breakdown in the classical equations of motion. We support and illustrate (a)-(d) by calculating the quantum transition across the de Sitter like throat connecting asymptotically classical, inflating histories in the no-boundary quantum state. This supplies probabilities for how a classical history on one side transitions and branches into a range of classical histories on the opposite side. We also comment on the implications of (a)-(d) for the dynamics of black holes and eternal inflation.
description: 37 pages, 5 figures, minor corrections, results not changed
Inference of a competing risks model with partially observed failure causes under improved adaptive type-II progressive censoring
Creators: name: Dutta, Subhankar
name: Kayal, Suchandan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences
subject: 62N02, 62F10, 62F15

description: In this paper, a competing risks model is analyzed based on improved adaptive type-II progressive censored sample (IAT-II PCS). Two independent competing causes of failures are considered. It is assumed that lifetimes of the competing causes of failure follow exponential distributions with different means. Maximum likelihood estimators (MLEs) for the unknown model parameters are obtained. Using asymptotic normality property of MLE, the asymptotic confidence intervals are constructed. Existence and uniqueness properties of the MLEs are studied. Further, bootstrap confidence intervals are computed. The Bayes estimators are obtained under symmetric and asymmetric loss functions with non-informative and informative priors. For informative priors, independent gamma distributions are considered. Highest posterior density (HPD) credible intervals are obtained. A Monte Carlo simulation study is carried out to compare performance of the established estimates. Furthermore, three different optimality criteria are proposed to obtain the optimal censoring plan. Finally, a real-life data set is considered for illustrative purposes.
Additional file 2 of Activation of circulating TFH17 cells associated with activated naive and double negative 2 B cell expansion, and disease activity in systemic lupus erythematosus patients
Creators: name: Khunsri, Tipanan
name: Thawornpan, Pongsakorn
name: Tianpothong, Pachara
name: Suangtamai, Thanitta
name: Ngamjanyaporn, Pintip
name: Leepiyasakulchai, Chaniya
name: Wangriatisak, Kittikorn
name: Pisitkun, Prapaporn
name: Chootong, Patchanee
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 2
Application of various machine learning models for fault detection in the refrigeration system of a brewing company
Creators: name: Anusak Luekiangkhamla
name: Natee Panagant
name: Sujin Bureerat
name: Nantiwat Pholdee
Publisher: name: Faculty of Engineering, Khon Kaen University
Year: 2023
Subjects: Predictive maintenance
Preventive management
Refrigeration system
Machine learning model
Data analysis
Fault detection

description: Engineering and Applied Science Research, 50, 2, 149-154
The Slepian zero set, and Brownian bridge embedded in Brownian motion by a spacetime shift
Creators: name: Pitman, Jim
name: Tang, Wenpin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60G17, 60J55, 60J65

description: This paper is concerned with various aspects of the Slepian process $(B_{t+1} - B_t, t \ge 0)$ derived from a one-dimensional Brownian motion $(B_t, t \ge 0 )$. In particular, we offer an analysis of the local structure of the Slepian zero set $\{t : B_{t+1} = B_t \}$, including a path decomposition of the Slepian process for $0 \le t \le 1$. We also establish the existence of a random time $T$ such that $T$ falls in the the Slepian zero set almost surely and the process $(B_{T+u} - B_T, 0 \le u \le 1)$ is standard Brownian bridge.
description: 28 pages, 3 figures and 3 tables. This paper is published by http://ejp.ejpecp.org/article/view/3911
Neutralization profiles of HIV-1 viruses from the VRC01 Antibody Mediated Prevention (AMP) trials
Creators: name: Mgodi, Nyaradzo
name: Hural, John
name: Thebus, Ruwayhida
name: Eaton, Amanda
name: Karuna, Shelly
name: Cohen, Myron S.
name: Matten, David
name: Ndabambi, Nonkululeko
name: Mielke, Dieter
name: Seaman, Michael S.
name: Kaldine, Haajira
name: Moore, Penny L.
name: Montefiori, David
name: Giorgi, Elena E.
name: Gwashu-Nyangiwe, Asanda
name: Morris, Lynn
name: Beaume, Nicolas
name: McElrath, M. Juliana
name: Huang, Yunda
name: van Dorsten, Rebecca T.
name: Corey, Lawrence
name: Anthony, Colin
name: Davis, Amanda S. Woodward
name: Edupuganti, Srilatha
name: York, Talita
name: Modise, Tandile
name: Yssel, Anna E. J.
name: Mapengo, Rutendo E.
name: Mkhize, Nonhlanhla N.
name: Westfall, Dylan H.
name: Kgagudi, Prudence
name: Williamson, Carolyn
name: Gilbert, Peter B.
name: Mullins, James I.
name: Domin, Elizabeth
name: Bekker, Valerie
name: Deng, Wenjie
name: Korber, Bette
name: Lambson, Bronwen
name: DeCamp, Allan
Publisher: name: Public Library of Science
Year: 2023

description: The VRC01 Antibody Mediated Prevention (AMP) efficacy trials conducted between 2016 and 2020 showed for the first time that passively administered broadly neutralizing antibodies (bnAbs) could prevent HIV-1 acquisition against bnAb-sensitive viruses. HIV-1 viruses isolated from AMP participants who acquired infection during the study in the sub-Saharan African (HVTN 703/HPTN 081) and the Americas/European (HVTN 704/HPTN 085) trials represent a panel of currently circulating strains of HIV-1 and offer a unique opportunity to investigate the sensitivity of the virus to broadly neutralizing antibodies (bnAbs) being considered for clinical development. Pseudoviruses were constructed using envelope sequences from 218 individuals. The majority of viruses identified were clade B and C; with clades A, D, F and G and recombinants AC and BF detected at lower frequencies. We tested eight bnAbs in clinical development (VRC01, VRC07-523LS, 3BNC117, CAP256.25, PGDM1400, PGT121, 10–1074 and 10E8v4) for neutralization against all AMP placebo viruses (n = 76). Compared to older clade C viruses (1998–2010), the HVTN703/HPTN081 clade C viruses showed increased resistance to VRC07-523LS and CAP256.25. At a concentration of 1μg/ml (IC80), predictive modeling identified the triple combination of V3/V2-glycan/CD4bs-targeting bnAbs (10-1074/PGDM1400/VRC07-523LS) as the best against clade C viruses and a combination of MPER/V3/CD4bs-targeting bnAbs (10E8v4/10-1074/VRC07-523LS) as the best against clade B viruses, due to low coverage of V2-glycan directed bnAbs against clade B viruses. Overall, the AMP placebo viruses represent a valuable resource for defining the sensitivity of contemporaneous circulating viral strains to bnAbs and highlight the need to update reference panels regularly. Our data also suggests that combining bnAbs in passive immunization trials would improve coverage of global viruses.
Vita apostolica als Lebensnorm in der Alten Kirche
Creators: name: Frank, Karl Suso
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 8 Nr. 2 (1979): Internationale katholische Zeitschrift Communio, Band 8, Heft 2
Non-Hormonal Contraception
Creators: name: Howard, Sarah Anne
name: Benhabbour, Soumya Rahima
Publisher: name: MDPI
Year: 2023

description: While hormonal contraceptives are efficacious and available in several forms for women, perception of safety and concern over side effects are a deterrent for many. Existing non-hormonal contraceptives include permanent sterilization, copper intrauterine devices (IUDs), chemical/physical barriers such as spermicides and condoms, as well as traditional family planning methods including withdrawal and the rhythm method. Individuals who wish to retain their fertility in the future can achieve highest adherence and efficacy with long-acting, reversible contraceptives (LARCs), though there is only one, the copper IUD, that is non-hormonal. As rates of unintended pregnancies remain high with existing contraceptive options, it is becoming increasingly attractive to develop novel pregnancy prevention methods for both women and men. Non-hormonal contraceptives can target a variety of critical reproductive processes discussed here. This review focuses on identified non-hormonal contraceptive targets and subsequent drug candidates in development.
Gibt es Laien in der Kirche?
Creators: name: Balthasar, Hans Urs Von
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 8 Nr. 2 (1979): Internationale katholische Zeitschrift Communio, Band 8, Heft 2
Monofunctional intermediates for ligand-dependent target protein degradation
Creators: name: Wang, Shaomeng
name: Li, Yangbing
name: Aguilar, Angelo
name: Zhou, Bing
name: Hu, Jiantao
name: Xu, Fuming
name: Qin, Chong
name: Hu, Yang
name: Xiang, Weiguo
name: Rej, Rohan
name: YANG, Jiuling
name: HAN, Xin
name: BAl, Longchuan
name: YANG, Chao-Yie
Publisher: name: My University
Year: 2022

description: The present disclosure provides monofunctional synthetic intermediates for the preparation of small-molecule drug conjugates. Coupling the monofunctional synthetic intermediates of this disclosure with an inhibitor of a target protein of interest, e.g., an oncogenic protein inhibitor, e.g., a BET bromodomain inhibitor or MDM2 inhibitor, provides a heterobifunctional small-molecule that simultaneously binds the target protein and a ubiquitin ligase, enabling ubiquitination and degradation of the target protein.
Bayesian reconstruction of memories stored in neural networks from their connectivity
Creators: name: Goldt, Sebastian
name: Krzakala, Florent
name: Zdeborová, Lenka
name: Brunel, Nicolas
Publisher: name: arXiv
Year: 2021
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Machine Learning (stat.ML)
subject: FOS: Biological sciences
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The advent of comprehensive synaptic wiring diagrams of large neural circuits has created the field of connectomics and given rise to a number of open research questions. One such question is whether it is possible to reconstruct the information stored in a recurrent network of neurons, given its synaptic connectivity matrix. Here, we address this question by determining when solving such an inference problem is theoretically possible in specific attractor network models and by providing a practical algorithm to do so. The algorithm builds on ideas from statistical physics to perform approximate Bayesian inference and is amenable to exact analysis. We study its performance on three different models, compare the algorithm to standard algorithms such as PCA, and explore the limitations of reconstructing stored patterns from synaptic connectivity.
description: Code available at https://github.com/sgoldt/reconstructing_memories
Technological Vocational Center Pasture Funds: Experience of Conservation of Biocultural Heritage in the Semi-Arid of Bahia, Brazil
Creators: name: Troilo, Gabriel
name: Lopes, Nelson De Jesus
name: Ferreira, Márcio Harrison Dos Santos
name: Nogueira, Mário Ferreira
name: Gama, Erasto
name: Carvalho, Aurélio José Antunes De
Publisher: name: figshare
Year: 2020
Subjects: subject: 70302 Agronomy
subject: FOS: Agriculture, forestry and fisheries

description: Trabalho publicado Cadernos de Agroecologia –ISSN 2236-7934 -Anais do XI Congresso Brasileiro de Agroecologia, São Cristóvão, Sergipe -v. 15, no 2, 2020
Gastarbeiter: Ghetto oder Bürger?
Creators: name: Freudenfeld, Burghard
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 8 Nr. 1 (1979): Internationale katholische Zeitschrift Communio, Band 8, Heft 1
Heisenberg-limited qubit readout with two-mode squeezed light
Creators: name: Didier, Nicolas
name: Kamal, Archana
name: Oliver, William D.
name: Blais, Alexandre
name: Clerk, Aashish A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We show how to use two-mode squeezed light to exponentially enhance cavity-based dispersive qubit measurement. Our scheme enables true Heisenberg-limited scaling of the measurement, and crucially, is not restricted to small dispersive couplings or unrealistically long measurement times. It involves coupling a qubit dispersively to two cavities, and making use of a symmetry in the dynamics of joint cavity quadratures (a so-called quantum-mechanics-free subsystem). We discuss the basic scaling of the scheme and its robustness against imperfections, as well as a realistic implementation in circuit quantum electrodynamics.
description: 5 pages, 4 figures, Supplemental Material