cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Analysis of hydration and subchondral bone density on the viscoelastic properties of bovine articular cartilage
Creators: name: Crolla, Joseph P.
name: Lawless, Bernard M.
name: Cederlund, Anna A.
name: Aspden, Richard M.
name: Espino, Daniel M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Computational Biology

description: Additional file 1. SupplementaryData.
title: Disputed Meanings of Women’s Liberation : Social Tensions and Symbolic Struggles During Angolan Independence
Creators: name: Figueiredo, Fábio Baqueiro
name: Institute Of African Studies
name: Bayreuth Academy Of Advanced African Studies
Publisher: name: University of Bayreuth
Year: 2022
Subjects: subject: Women
subject: women liberation
subject: New Man
subject: moralities
subject: gender relations
subject: nation-building
subject: Angola
subject: 320
subject: 960

description: During the armed struggle, the Popular Movement for the Liberation of Angola (MPLA) supported women's liberation and appointed women to several political, logistical, and military positions. Meanwhile, in colonial society, changes in economic activities, access to formal education, and urban sociability resulted in a more significant female presence in public spaces. After independence, women's liberation rose to prominence in a context of internal conflict and economic disruption. The new government promoted the “New Man” and a host of associated social personae, all of which were defined by a set of moral qualities individuals were expected to comply with if they wanted to qualify as legitimate actors in the making of independent Angola. Women ought to engage in “National Reconstruction” by joining the Organization of Angolan Women (OMA), which focused on literacy and hygienist campaigns aimed at fighting “obscurantism”. However, many urban women had their own agendas, which called for changes in gender roles in both public and domestic realms. This paper seeks to highlight the shifting gender patterns in Luanda and rural guerrilla zones during the late colonial period, and then analyze how, after independence, different groups of women conceived their place in the building of the new nation, and how the State tried to “domesticate” the possibilities of women's activism as such, in symbolic as well as practical ways.
Toxicity of natural radioactivity in water samples from a gold mine in Gauteng Province, South Africa
Creators: name: Kamunda, Caspah
Publisher: name: EQA - International Journal of Environmental Quality
Year: 2020
Subjects: Broad energy germanium detector, natural radioactivity; activity concentration, gold mine, radiological hazard

description: A radiological toxicity assessment of natural radioactivity in water samples from a gold mine in the Gauteng Province of South Africa was evaluated. In this study, 29 water samples were collected from the mine and 5 were collected from a control area. A broad energy germanium detector was used to measure the activity concentrations of Uranium-238, Thorium-232, and Potassium-40. Their activity concentrations were then used to calculate radiological hazard parameters in water for the area. The average value of the Radium Equivalent Activity (Raeq) in water samples from the mining area and from the control area was found to be lower than the allowable limit of 370 Bq.L-1. The Annual Effective Dose Equivalent (AEDE) was found to be equal to 1.29×10-3 mSv.y-1, a value below worldwide average of 2.4 mSv.y-1 for natural radiation. The external hazard (Hex) and internal hazard (Hin) index for water samples from the mining area were less than unity, making water samples safe to the population in the area.
description: EQA - International Journal of Environmental Quality, Vol 41 (2021)
A computerized MRI biomarker quantification scheme for a canine model of Duchenne muscular dystrophy
Creators: name: An, Hongyu
name: Styner, Martin A.
name: Fan, Zheng
name: Shiloh-Malawsky, Yael
name: Wang, Jiahui
name: Walter, Glenn
name: Vandenborne, Krista
name: Kornegay, Joe N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Golden retriever muscular dystrophy (GRMD) is a widely used canine model of Duchenne muscular dystrophy (DMD). Recent studies have shown that magnetic resonance imaging (MRI) can be used to non-invasively detect consistent changes in both DMD and GRMD. In this paper, we propose a semi-automated system to quantify MRI biomarkers of GRMD.
Metabolic Atlas – exploration and visualization of metabolic networks for model organisms
Creators: name: Anton, Mihail
name: Nanjiang Shu
name: Hyltander, Ingrid
name: Klang, Malin
name: Johnsson, Per
name: Huang, Shan
name: L. Thomas Svensson
name: Nielsen, Jens
Publisher: name: F1000 Research Limited
Year: 2022

description: Models in systems biology are used to understand biological processes by facilitating data interpretation, analysis, and prediction. By joining thousands of reactions, metabolites, and genes into large metabolic networks, genome-scale metabolic models (GEMs) have become valuable tools to study metabolism. The incorporation of enzymatic parameters is, for example, one of the ways to further improve the prediction of GEMs, in addition to the integration of omics data.

 Metabolic Atlas, through the web platform freely available at metabolicatlas.org, presents the entire content of open GEMs for easy browsing and analysis. This is achieved through both tabular and map views (2D and 3D). In addition, Metabolic Atlas aims to meet the needs of the community through the development of specific tools and features through iterative releases.

 The history of Metabolic Atlas began with a focus on the human metabolic model (Pornputtapong et al., 2015). The present website has been re-developed from the ground up, following open-source standards, by first integrating Human1, an integration and extensive curation of the most recent human metabolic models (Robinson et al., 2020), and Yeast8, a consensus metabolic model for S. cerevisiae (Lu et al., 2019). Following a database redesign and the addition of a performant 3D viewer, 5 more models have been integrated (Wang et al., 2021). A new major release is under active development, aiming to further facilitate computational applications and metabolic engineering.
Generalized Survival Probability
Creators: name: Zarate-Herrada, David A.
name: Santos, Lea F.
name: Torres-Herrera, E. Jonathan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The survival probability measures the probability that a system taken out of equilibrium has not yet moved out from its initial state. Inspired by the generalized entropies used to analyze nonergodic states, we introduce a generalized version of the survival probability, and discuss how it can assist studies of the structure of the eigenstates and ergodicity.
description: 10 pages, 6 figures. This work is dedicated to Professor Giulio Casati on the occasion of his 80th birthday in 2022, Professor Felix Izrailev on the occasion of his 80th birthday in 2021, and Professor Vladimir Zelevinsky on the occasion of his 85th birthday in 2022
Adaptive sliding mode control for robotic manipulators by hybridisation
Creators: name: Chong, Sze San
Publisher: name: CQUniversity
Year: 2022
Subjects: subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: In this thesis, the trajectory control of robotic manipulators is studied. The thesis consists of two parts.The first part is the comparison studies of trajectory control of a two link robotic manipulator using various control laws. Simulations are presented to show the merits of each control law and discussions are given.The second part is development of new control laws. A new control law is formulated by combining two existing control laws and the performance of the hybrid control law is assessed by simulating the action of the two link robotic manipulator controlled by the new hybrid control law. The effect of Regressor Matrix modification on the performance of the robotic manipulator is then studied by using the control law of Slotine and Li. In order to find out whether regressor matrix modification and composite adaptation can further improve the performance of a control law, these two modifications are then incorporated into the new hybrid control law and the performance of the manipulator is assessed. Simulations are presented to verify the effectiveness of the approach proposed.
ЭНДОКРИНОЛОГИЧЕСКАЯ СЛУЖБА ПРИ ОЖИРЕНИЕ САМАРКАНДСКОЙ ОБЛАСТИ СОВРЕМЕННОЕ СОСТОЯНИЕ И ПЕРСПЕКТИВЫ РАЗВИТИЯ
Creators: name: Тогаева, Гулнора
name: Давранова, Азиза
Publisher: name: Zenodo
Year: 2023

description: В статье представлена ожирение как эндокринными патологиями населения Самаркандской области за период 2017-2021 гг. Приводятся основные нормативные документы, регулирующие оказание медицинской помощи и профилактике.
Marie Curie Alumni Association welcomes rights retention for researchers
Creators: name: Shawrav, Mostafa Moonir
Publisher: name: Zenodo
Year: 2020

description: The Marie Curie Alumni Association is a strong supporter of open science and for the empowerment of researchers, for example as described in our February 2020 statement ‘Researchers call on EU institutions to ensure free circulation of scientific knowledge’, our December 2019 statement ‘Researchers support sharing of peer-reviewed research without embargoes and restrictions’, our September 2018 ‘Joint Statement on Open Access for Researchers via Plan S’ and our May 2019 input to the ‘Stakeholder consultation on the future of scholarly publishing and scholarly communication’. Our previous efforts and positions align well with today’s announcement from cOAlition S on a new ‘Rights Retention Strategy’, which we therefore warmly welcome.  Researchers should never be forced by a publisher to hand over the rights to their work, and we reiterate our previous call upon those publishers that still force barriers on the flow of knowledge, to modernize and join the numerous publishers that already today allow and encourage researchers to share their research findings without embargoes and restrictions. As a contributor to the cOAlition S taskforce on ‘Monitoring the effects of Plan S on Research and Scholarly Communication’, the Marie Curie Alumni Association commits to remain a constructive partner and positive force in the important endeavour of advancing open science while empowering researchers. Signed by Mostafa Moonir Shawrav (Chair of the Marie Curie Alumni Association) on July 15, 2020. Marie Curie Alumni Association, Avenue des Arts 24, B-1000, Brussels, Belgium Web: https://www.mariecuriealumni.eu ; This statement is released under a CC BY license. Please reference this statement using http://doi.org/10.5281/zenodo.3945884 Link to all MCAA statements: https://zenodo.org/communities/mcaa/
Improving Fairness in Adaptive Social Exergames via Shapley Bandits
Creators: name: Gray, Robert C.
name: Villareale, Jennifer
name: Fox, Thomas B.
name: Dallal, Diane H.
name: Ontañón, Santiago
name: Arigo, Danielle
name: Jabbari, Shahin
name: Zhu, Jichen
Publisher: name: arXiv
Year: 2023
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Algorithmic fairness is an essential requirement as AI becomes integrated in society. In the case of social applications where AI distributes resources, algorithms often must make decisions that will benefit a subset of users, sometimes repeatedly or exclusively, while attempting to maximize specific outcomes. How should we design such systems to serve users more fairly? This paper explores this question in the case where a group of users works toward a shared goal in a social exergame called Step Heroes. We identify adverse outcomes in traditional multi-armed bandits (MABs) and formalize the Greedy Bandit Problem. We then propose a solution based on a new type of fairness-aware multi-armed bandit, Shapley Bandits. It uses the Shapley Value for increasing overall player participation and intervention adherence rather than the maximization of total group output, which is traditionally achieved by favoring only high-performing participants. We evaluate our approach via a user study (n=46). Our results indicate that our Shapley Bandits effectively mediates the Greedy Bandit Problem and achieves better user retention and motivation across the participants.
Experimental evaluation of ultrasound-guided 3D needle steering in biological tissue
Creators: name: Vrooijink, Gustaaf J.
name: Abayazid, Momen
name: Alterovitz, Ron
name: Misra, Sarthak
name: Patil, Sachin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: In this paper, we present a system capable of automatically steering bevel-tip flexible needles under ultrasound guidance towards stationary and moving targets in gelatin phantoms and biological tissue while avoiding stationary and moving obstacles. We use three-dimensional (3D) ultrasound to track the needle tip during the procedure.
Deformable M-Reps for 3D Medical Image Segmentation
Creators: name: Joshi, Sarang
name: Chen, James Z.
name: Pizer, Stephen M.
name: Jiroutek, Michael R.
name: Fletcher, P. Thomas
name: Gash, A. Graham
name: Chaney, Edward L.
name: Lu, Conglin
name: Yushkevich, Paul
name: Muller, Keith E.
name: Tracton, Gregg
name: Thall, Andrew
name: Glotzer, John M.
name: Fridman, Yonatan
name: Fritsch, Daniel S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: M-reps (formerly called DSLs) are a multiscale medial means for modeling and rendering 3D solid geometry. They are particularly well suited to model anatomic objects and in particular to capture prior geometric information effectively in deformable models segmentation approaches. The representation is based on figural models, which define objects at coarse scale by a hierarchy of figures – each figure generally a slab representing a solid region and its boundary simultaneously. This paper focuses on the use of single figure models to segment objects of relatively simple structure.
Publications and Resources of the International Institute of Rural Reconstruction in Myanmar
Creators: name: Barbon, Wilson John
Publisher: name: Zenodo
Year: 2022
Subjects: climate smart agriculture; climate change; agriculture; food security

description: List of publications and resources generated by IIRR in Myanmar from its work in the climate smart villages in Myanmar supported by IDRC-Canada and CGIAR-CCAFS implemented between 2017 to 2021.
An Adaptive Plug-and-Play Network for Few-Shot Learning
Creators: name: Li, Hao
name: Li, Li
name: Huang, Yunmeng
name: Li, Ning
name: Zhang, Yongtao
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Few-shot learning (FSL) requires a model to classify new samples after learning from only a few samples. While remarkable results are achieved in existing methods, the performance of embedding and metrics determines the upper limit of classification accuracy in FSL. The bottleneck is that deep networks and complex metrics tend to induce overfitting in FSL, making it difficult to further improve the performance. Towards this, we propose plug-and-play model-adaptive resizer (MAR) and adaptive similarity metric (ASM) without any other losses. MAR retains high-resolution details to alleviate the overfitting problem caused by data scarcity, and ASM decouples the relationship between different metrics and then fuses them into an advanced one. Extensive experiments show that the proposed method could boost existing methods on two standard dataset and a fine-grained datasets, and achieve state-of-the-art results on mini-ImageNet and tiered-ImageNet.
description: 5 pages, 4 figures
Optimizing venerable bioinformatics software: A profile-guided approach
Creators: name: Larralde, Martin
Publisher: name: F1000 Research Limited
Year: 2022

description: With an ever-increasing amount of available data, scalability problems are much more of a concern than they were 20 years ago, and climate change issues urges for greener computing. In bioinformatics, a few methods have become de-facto standards to approach specific issues such as gene-calling, multiple sequence alignment, or protein domain annotation. These tools are now the basis of numerous annotation pipelines that are executed thousands of time daily. Academia however favors scientific novelty over efficiency, and C or C++ code is more than enough to be categorized as high-performance software.

 In this work, we use profiling to identify critical parts of established bioinformatics methods. We then employ several optimization techniques to make these tools more efficient. We show how inlining a few functions halve the runtime of the PRANK aligner; how caching alignment matrices used by trimAl reduce the runtime 10-fold; how SIMD speeds up the gene scoring step of Prodigal; and how parallel hashing in FastANI increases the efficiency on multi-core machines.

 The goal of this software engineering experiment is to introduce some efficient programming habits to the community, and to change the perspective about ubiquitous software we use brainlessly in our pipelines. More practically, we provide several of these patches as Python packages to be used as drop-in replacements for the originals. As a perspective, we present some general figures about the energetic cost of computing, and how much CO2 can be saved with the aforementioned optimizations.
The Clinical Profile of Merkel Cell Carcinoma in Mainland China
Creators: name: Song, Philip I.
name: Liang, Hao
name: Jiang, Yi-Qun
name: Qiao, You-Lin
name: Smith, Jennifer S.
name: Wei, Wen-Qiang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Merkel cell carcinoma (MCC) is an aggressive cutaneous malignancy, but little is known about the presence or characteristics of MCC in mainland China. A retrospective chart review was conducted to describe the clinical profile of Merkel cell carcinoma in China.
Gestational treatment with cocaine and fluoxetine alters oxytocin receptor number and binding affinity in lactating rat dams
Creators: name: Middleton, Christopher
name: Johns, Josephine M.
name: Lubin, Deborah A.
name: Walker, Cheryl H.
name: Joyner, Paul
name: Hofler, Vivian
name: McMurray, Matthew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Cocaine administered chronically throughout gestation has been correlated with deficits in maternal behavior, increased maternal aggressive behavior and decreased oxytocin levels in rats. In addition to its effects on oxytocin levels, cocaine is a potent serotonergic, dopaminergic and noradrenergic reuptake inhibitor. Alterations in the dopaminergic and serotonergic systems have been suggested as possibly having a role in cocaine-induced maternal aggression. This study was in part, an attempt to understand some of the mechanisms by which cocaine increases postpartum aggression, particularly as they relate to changes in the oxytocin system.
Meneropong Dirgantara Dunia Pasca Covid – Kemana Arah Dirgantara Indonesia
Creators: name: Hakim, Chappy
name: IASI, Jerman
Publisher: name: Zenodo
Year: 2020
Subjects: webinar IASI
Dirgantara Indonesia
COVID-19

description: Dunia dirgantara termasuk salah satu sisi yang terkena dampak sangat besar dengan adanya pandemi Covid-19 saat ini. Jumlah penumpang menurun drastis bahkan sampai titik yang paling rendah, dengan adanya berbagai langkah-langkah pencegahan penularan Covid-19, termasuk larangan bepergian dengan menggunakan pesawat terbang.
 Perusahaan pesawat terbang mulai terkena dampaknya dan melakukan banyak tindakan untuk menyelamatkan perekonomian perusahaan dan karyawannya.
 Bagaimana dengan dunia dirgantara Indonesia, kemana akan melanglah setelah pandemi ini?
 Mantan KSAU Republik Indonesia, Bapak Chappy Hakim membagikan pandangannya pada acara Webinar IASI Jerman yang berjudul : "Meneropong Dirgantara Dunia Pasca COVID. Kemana Arah Dirgantara Indonesia"
 Demikian pula Prof. Dr.-Ing. Yulfian Aminanda turut mempresentasikan apa yang dapat dilakukan oleh Indonesia pada saat pandemi ini berakhir.
Emphasizing Unseen Words: New Vocabulary Acquisition for End-to-End Speech Recognition
Creators: name: Qu, Leyuan
name: Weber, Cornelius
name: Wermter, Stefan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computation and Language (cs.CL)
subject: Sound (cs.SD)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Due to the dynamic nature of human language, automatic speech recognition (ASR) systems need to continuously acquire new vocabulary. Out-Of-Vocabulary (OOV) words, such as trending words and new named entities, pose problems to modern ASR systems that require long training times to adapt their large numbers of parameters. Different from most previous research focusing on language model post-processing, we tackle this problem on an earlier processing level and eliminate the bias in acoustic modeling to recognize OOV words acoustically. We propose to generate OOV words using text-to-speech systems and to rescale losses to encourage neural networks to pay more attention to OOV words. Specifically, we enlarge the classification loss used for training neural networks' parameters of utterances containing OOV words (sentence-level), or rescale the gradient used for back-propagation for OOV words (word-level), when fine-tuning a previously trained model on synthetic audio. To overcome catastrophic forgetting, we also explore the combination of loss rescaling and model regularization, i.e. L2 regularization and elastic weight consolidation (EWC). Compared with previous methods that just fine-tune synthetic audio with EWC, the experimental results on the LibriSpeech benchmark reveal that our proposed loss rescaling approach can achieve significant improvement on the recall rate with only a slight decrease on word error rate. Moreover, word-level rescaling is more stable than utterance-level rescaling and leads to higher recall rates and precision on OOV word recognition. Furthermore, our proposed combined loss rescaling and weight consolidation methods can support continual learning of an ASR system.
description: Neural Networks, Volume 161, April 2023, Pages 494-504
A non-transformed oligodendrocyte precursor cell line, OL-1, facilitates studies of insulin-like growth factor-I signaling during oligodendrocyte development
Creators: name: Lagarde, William H.
name: Benjamin, Robert
name: Heerens, Ann T.
name: Ye, Ping
name: D’Ercole, A. Joseph
name: Cohen, Rick I.
name: Moats-Staats, Billie M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The process by which oligodendrocyte progenitors differentiate into mature oligodendrocytes is complex and incompletely understood in part because of the paucity of oligodendrocyte precursors cell lines that can be studied in culture. We have developed a non-immortalized rat oligodendrocyte precursor line, called OL-1, which behaves in a fashion consistent with developing oligodendrocytes in vivo. This OL-1 line provides a model for the study of oligodendrocyte development and offers an alternative to the CG-4 cell line. When OL-1 cells are propagated in conditioned growth media, they have morphology consistent with immature oligodendrocytes and exhibit A2B5 antigen positive and myelin basic protein-negative immunoreactivity. Withdrawal of conditioned growth media and culture in serum-free medium results in OL-1 cell maturation, manifested by a shift to myelin basic protein-positive immunoreactivity, A2B5 antigen-negative immunoreactivity, decreased NG2 mRNA expression, increased expression of proteolipid protein mRNA, and increased expression of CNP protein. In addition, the expression of proteolipid protein and its splicing variant DM-20 exhibit a pattern that is similar to brain proteolipid protein expression during development. When OL-1 cells are exposed to Insulin-like growth factor-I, there are significant increases in proteolipid protein mRNA expression ( p < 0.05), the number of cell processes ( p < 0.05), and cell number ( p < 0.05). Treatment with the caspase inhibitors Z-DEVD-FMK and Z-VAD-FMK (inhibitors of caspases 3, 6, 7, 8, 10 and 1, 3, 4, respectively), Insulin-like growth factor-I, or both, results in a similar increase in cell number. Because Insulin-like growth factor-I does not substantially increase the BrdU labeling of OL-1 cells, these data collectively indicate that Insulin-like growth factor-I increases OL-1 cell number predominately by promoting survival, rather than stimulating proliferation. This non-immortalized oligodendrocyte precursor cell line, therefore, exhibits behavior consistent with the in vivo development of oligodendrocytes and provides an excellent model for the study of developing oligodendrocytes.
Dimensions of couples’ sexual communication, relationship satisfaction, and sexual satisfaction : a meta-analysis
Creators: name: Mallory, Allen Burnell Sears
Publisher: name: The University of Texas at Austin
Year: 2018
Subjects: Couples
Sexual communication
Sexual satisfaction
Relationship satisfaction
Meta-analysis

description: This meta-analysis examined the associations between sexual communication and both relationship and sexual satisfaction. The meta-analysis included 83 studies with 183 unique effect sizes which represented 40,594 unique individuals. The random effects multi-level model evidenced a positive association between sexual communication and both relationship (r = .38) and sexual satisfaction (r = .42). The effect size for sexual satisfaction was significantly larger for compared to the effect size for relationship satisfaction. For sexual satisfaction, the quality of sexual communication (r = 48) was larger compared to both frequency (r =.34) and sexual self-disclosure (r =, .33). Relationship status remained a significant moderator after accounting for age, and relationship length; however, for relationship satisfaction mixed samples differed only from married samples and for sexual satisfaction, and mixed samples differed only from dating samples. In a subset of dyadic studies, accounting for both partners' sexual communication attenuated the effect sizes for the association between sexual communication and both relationship satisfaction and sexual satisfaction. Finally, a countries level of individualism moderated the association between sexual communication and sexual satisfaction. Results suggest that how sexual communication is measured, sample characteristics, and cultural factors have important implications for understanding the association between sexual communication and both relationship and sexual satisfaction
The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis.
Creators: name: Cortés, Alba
name: Martin, John
name: Rosa, Bruce A
name: Stark, Klara A
name: Clare, Simon
name: McCarthy, Catherine
name: Harcourt, Katherine
name: Brandt, Cordelia
name: Tolley, Charlotte
name: Lawley, Trevor D
name: Mitreva, Makedonka
name: Berriman, Matthew
name: Rinaldi, Gabriel
name: Cantacessi, Cinzia
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research Article

description: Acknowledgements: The authors would like to thank Mandy Sanders (Wellcome Sanger Institute) for technical assistance.
description: Funder: Wellcome Trust; funder-id: http://dx.doi.org/10.13039/100010269
description: Funder: Fundación Alfonso Martín Escudero; funder-id: http://dx.doi.org/10.13039/100008052
description: Funder: University of Cambridge
description: Increasing evidence shows that the host gut microbiota might be involved in the immunological cascade that culminates with the formation of tissue granulomas underlying the pathophysiology of hepato-intestinal schistosomiasis. In this study, we investigated the impact of Schistosoma mansoni infection on the gut microbial composition and functional potential of both wild type and microbiome-humanized mice. In spite of substantial differences in microbiome composition at baseline, selected pathways were consistently affected by parasite infection. The gut microbiomes of infected mice of both lines displayed, amongst other features, enhanced capacity for tryptophan and butyrate production, which might be linked to the activation of mechanisms aimed to prevent excessive injuries caused by migrating parasite eggs. Complementing data from previous studies, our findings suggest that the host gut microbiome might play a dual role in the pathophysiology of schistosomiasis, where intestinal bacteria may contribute to egg-associated pathology while, in turn, protect the host from uncontrolled tissue damage.
MPEC 2023-U164 : DAILY ORBIT UPDATE (2023 October 21)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Combination effect of growth enhancers and carbon sources on synthesis of single-walled carbon nanotubes from solid carbon growth seeds
Creators: name: Wang, Mengyue
name: Liu, Yuanjia
name: Maekawa, Manaka
name: Arifuku, Michiharu
name: Kiyoyanagi, Noriko
name: Inoue, Taiki
name: Kobayashi, Yoshihiro
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In the synthesis of highly crystalline single-walled carbon nanotubes (SWCNTs), high growth temperatures are preferred, while the formation of impurity amorphous carbon (a-C) causes the termination of SWCNT growth and degrades its properties. To remove this by-product, H2O and CO2 have been employed in metal-catalyzed SWCNT growth systems because of their oxidizing ability. Recently, nonmetallic nanoparticles have become one of the growth seed candidates because of their high melting points and fewer metal impurities. In this study, by using nanodiamond-derived carbon nanoparticles as the solid growth seeds, we investigated the effect of CO2 and H2O on high-temperature SWCNT growth with two types of carbon-source supplies: C2H2 and C2H4. In this growth system, H2O showed oxidizing ability to etch a-C with either carbon sources. CO2 exhibited a similar a-C formation-preventing role in C2H4-supplied growth and achieved higher-purity SWCNTs with higher concentration of C2H4 than the case of H2O. However, in contrast to the other combinations, CO2 injection in the C2H2-supplied growth significantly enhanced the formation of a-C rather than the removal of it while the yield of SWCNTs was also increased, indicating the occurrence of the dehydration reaction between CO2 and C2H2. The present findings will lead to efficient growth of high-quality SWCNTs from nonmetallic growth seeds with the use of growth enhancers.
description: 41 pages, 14 figures, Accepted manuscript (Submitted 7 October 2022, Accepted 3 November 2022)
Insulin-like growth factor-I (IGF-I) inhibits neuronal apoptosis in the developing cerebral cortex in vivo
Creators: name: O’Kusky, John R.
name: Hodge, Rebecca D.
name: D’Ercole, A. Joseph
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Increased expression of insulin-like growth factor-I (IGF-I) in embryonic neural progenitors in vivo has been shown to accelerate neuron proliferation in the neocortex. In the present study, the in vivo actions of (IGF-I) on naturally occurring neuron death in the cerebral cortex were investigated during embryonic and early postnatal development in a line of transgenic (Tg) mice that overexpress IGF-I in the brain, directed by nestin genomic regulatory elements, beginning at least as early as embryonic day (E) 13. The areal density of apoptotic cells (NA, cells/mm2) at E16 in the telencephalic wall of Tg and littermate control embryos was determined by immunostaining with an antibody specific for activated caspase-3. Stereological analyses were conducted to measure the numerical density (NV, cells/mm3) and total number of immunoreactive apoptotic cells in the cerebral cortex of nestin/IGF-I Tg and control mice at postnatal days (P) 0 and 5. The volume of cerebral cortex and both the NV and total number of all cortical neurons also were determined in both cerebral hemispheres at P0, P5 and P270. Apoptotic cells were rare in the embryonic telencephalic wall at E16. However, the overall NA of apoptotic cells was found to be significantly less by 46% in Tg embryos. The volume of the cerebral cortex was significantly greater in Tg mice at P0 (30%), P5 (13%) and P270 (26%). The total number of cortical neurons in Tg mice was significantly increased at P0 (29%), P5 (29%) and P270 (31%), although the NV of cortical neurons did not differ significantly between Tg and control mice at any age. Transgenic mice at P0 and P5 exhibited significant decreases in the NV of apoptotic cells in the cerebral cortex (31% and 39%, respectively). The vast majority of these apoptotic cells (>90%) were judged to be neurons by their morphological appearance. Increased expression of IGF-I inhibits naturally occurring (i.e. apoptotic) neuron death during early postnatal development of the cerebral cortex to a degree that sustains a persistent increase in total neuron number even in the adult animal.
Retro jamming and Devolver Digital : how independent video games reject nostalgia
Creators: name: O’Brien, Morgan Clark
name: 0000-0001-7115-9463
Publisher: name: The University of Texas at Austin
Year: 2020
Subjects: Video games
Independent games
Retro jamming
Culture jamming
Nostalgia
Devolver Digital
Hotline Miami
Mother Russia Bleeds
Double Dragon
Luftrausers
Downwell

description: Since at least 2008 a noticeable trend has emerged in the world of independently made digital games. Independent game developers have begun to release games with retro-styled, anachronistic graphics and sound instead of attempting to compete with the increasingly more photorealistic visuals and lush musical scores of larger budget, so-called ‘triple-A’ (AAA) games. Increasingly, the field is labelling such games as instances of various types of nostalgia, in a move that precludes any other type of meaningful critical engagement. This dissertation reads the aesthetic techniques of several recent indie games as illustrative of a critical semiotic practice I am labeling “retro jamming”. Retro jamming performs anachronism as a post-conceptual subversive art form that is informed by a keen understanding of gaming culture and the history of the computer as medium of expression. The games examined herein were all created by small development teams from around the globe and published by Devolver Digital, an independent distributor based in Austin, Texas. The Devolver games discussed in this dissertation chart the initial emergence and codification of a formal-aesthetic mode (chapter one: Hotline Miami (Dennaton, 2012)), and the on-going discursive cycling between a baroque phase (chapter two: Mother Russia Bleeds (Le Cartel, 2016) and a minimalist period (chapter three: Luftrausers (Vlambeer, 2014) and Downwell (Moppin, 2015))
BOSHLANG'ICH SINF ONA TILI DARSLARIDA SO'ZLARNING SHAKL MA'NO TURLARI VA O'RGATISH METODIKASI
Creators: name: Abdiraimova, Xusnobod
Publisher: name: Zenodo
Year: 2023

description: Ushbu maqola boshlang'ich sinf ona tili darslarida so'zlarni shakl va ma'no turlari va ularni o'rgatish metodikasi va didaktik o'yinlardan iborat.Bu maqola o'quvchilarni og'zaki va yozma nutq boyligini oshiradi. So'z ma'nolarini bosqichma – bosqich o'quvchilarda oshirib borilsa maqsadga muvofiq bo'lardi.
Authorizing revolutionary constitutional change : constituent power, legitimacy, and the revolutionary constitutional amendment
Creators: name: Cozza, Joseph Francesco
Publisher: name: The University of Texas at Austin
Year: 2022
Subjects: Constitutional amendments
Legitimacy
Constituent power
Constitutional revolutions
Popular sovereignty
Referendums

description: Constitutions are critical links between a foundational past and an aspirational future. This dual role opens the door to significant disharmonies both within the text and between the document and the people. There are times, however, when efforts to reconcile growing disharmonies in a constitutional system are no longer sufficient, requiring a new approach that will transform the identity of the constitutional order. The periodic need for transformative change has led scholars to analyze constitutional revolutions and their role in constitutional systems. This dissertation examines how the amendment power can be used to legitimately produce a constitutional revolution, altering the core identity of a constitutional system. First, I argue that revolutionary amendments can be classified along two dimensions: institutional and socio-normative. While institutional amendments restructure the delegation of sovereignty in the state, socio-normative amendments shift the constitution’s core values and redefine the demos. Drawing on civic republican theory, I then argue that the process of enacting revolutionary amendments must approximate the primary constituent power by fostering citizen representation and deliberation in both the drafting and ratification of the amendment, mirroring mechanisms that would be used to draft a new constitution. In this way, the amendment can make a claim to a new popular sovereignty independent of the existing document. This theory, which I call the Approximation Thesis, can help determine when a revolutionary amendment will be seen as a legitimate constitutional change by the citizens of the state. Chapter 2 lays out the theoretical framework by introducing the concept of the revolutionary amendment and offering a normative assessment of the path to legitimation, connecting the concept to the literature on constituent power and popular sovereignty. The subsequent chapters provide empirical support for this theory. In doing so, I conduct in-depth case studies of revolutionary constitutional change in Ireland (Chapter 3) and the United Kingdom (Chapter 4), focusing specifically on the 2018 repeal of Ireland’s Eighth Amendment and the 2016-2021 Brexit process. In Chapter 5, I conduct experimental analysis in the United States to test the impact of participatory amendment procedures on the legitimacy of constitutional change, both ordinary and revolutionary.
Aerospace Industry - Research Institution and Research Management
Creators: name: Aminanda, Yulfian
name: IASI, Jerman
Publisher: name: Zenodo
Year: 2020
Subjects: Webinar IASI
Dirgantara Indonesia
COVID-19
Strategi

description: Dunia dirgantara termasuk salah satu sisi yang terkena dampak sangat besar dengan adanya pandemi Covid-19 saat ini. Jumlah penumpang menurun drastis bahkan sampai titik yang paling rendah, dengan adanya berbagai langkah-langkah pencegahan penularan Covid-19, termasuk larangan bepergian dengan menggunakan pesawat terbang.
 Perusahaan pesawat terbang mulai terkena dampaknya dan melakukan banyak tindakan untuk menyelamatkan perekonomian perusahaan dan karyawannya.
 Bagaimana dengan dunia dirgantara Indonesia, kemana akan melanglah setelah pandemi ini?
 Mantan KSAU Republik Indonesia, Bapak Chappy Hakim membagikan pandangannya pada acara Webinar IASI Jerman yang berjudul : "Meneropong Dirgantara Dunia Pasca COVID. Kemana Arah Dirgantara Indonesia"
 Demikian pula Prof. Dr.-Ing. Yulfian Aminanda turut mempresentasikan apa yang dapat dilakukan oleh Indonesia pada saat pandemi ini berakhir.
Kommt es zu einer Revision der Taufpraxis? Überlegungen in Frankreich und in der Bundesrepublik
Creators: name: Schmalz, Franz
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 26 Nr. 1 (1972): Herder Korrespondenz, Band 26, Heft 1
High fat diet-induced maternal obesity alters fetal hippocampal development
Creators: name: Lupu, Daniel S.
name: Niculescu, Mihai D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: The importance of maternal nutrition for fetal brain development is increasingly recognized. Previous studies have suggested that maternal obesity or maternal exposure to obesogenic diets may permanently alter brain structure and function in the offspring. To test whether maternal exposure to a high-fat diet, prior and during gestation, alters fetal hippocampal development, we fed 8-week old C57BL/6 females with a high-fat diet (60% calories from fat) for 10 weeks prior to matting and 17 days after. Fetal brains at embryonic day E17 were used to determine developmental changes in the hippocampus. We report that maternal exposure to the high-fat diet induced small for gestational age (SGA) status and fetal resorption. The proliferation of neural progenitors was increased in the neuroepithelium from hippocampus and cortex in fetuses from mothers fed the high-fat diet when compared to controls, but decreased within the dentate gyrus (DG). Apoptosis in the hippocampus was decreased (Ammon’s Horn and fimbria). The differentiation of calretinin-positive neurons within the DG was also decreased.
Шорин С.А. О понятии эффективности бюджетных расходов // Правовое и индивидуальное регулирование общественных отношений: проблемы теории и практики: Материалы IX Всероссийской научно-практической конференции аспирантов, соискателей, магистрантов и молодых ученых. – М.: РГУП, 2021. – 640 с. С. 454-461.
Creators: name: Shorin, Sergey
Publisher: name: figshare
Year: 2022
Subjects: subject: Law
subject: FOS: Law
subject: 150201 Finance
subject: FOS: Economics and business
subject: 160509 Public Administration
subject: FOS: Political science

description: В статье исследуется проблема понимания эффективности бюджетных расходов. Предлагается определение указанного понятия и дается рекомендация по его законодательному закреплению. Задача об эффективном расходовании бюджетных средств ставится во множестве нормативных правовых актов и публичных выступлений высокопоставленных государственных чиновников. Эту задачу решают ученые и специалисты-практики. В Бюджетном кодексе Российской Федерации эффективность использования бюджетных средств установлена в форме нормы-принципа, заложенной в основу бюджетной системы Российской Федерации. Однако понятие эффективности бюджетных расходов ни федеральными законами, ни подзаконными актами не закреплено, что делает актуальным исследование этого понятия.
SUPPLEMENTARY FIGURES & TABLES from Macaca mulatta is a good model for human mandibular fixation research
Creators: name: Haravu, Pranav N.
name: Abraha, Hyab Mehari
name: Shang, Michelle
name: Iriarte-Diaz, Jose
name: Taylor, Andrea B.
name: Reid, Russell R.
name: Ross, Callum F.
name: Panagiotopoulou, Olga
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: 110601 Biomechanics
subject: FOS: Health sciences
subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering
subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: Biomechanical and clinical studies have yet to converge on the optimal fixation technique for angle fractures, one of the most common and controversial fractures in terms of fixation approach. Prior pre-clinical studies have used a variety of animal models and shown abnormal strain environments exacerbated by less-rigid (single-plate) Champy fixation and chewing on the side opposite the fracture (contralateral chewing). However, morphological differences between species warrant further investigation to ensure that these findings are translational. Here we present the first study to use realistically loaded finite-element models to compare the biomechanical behaviour of human and macaque mandibles pre- and post-fracture and fixation. Our results reveal only small differences in deformation and strain regimes between human and macaque mandibles. In the human model, more-rigid biplanar fixation better approximated physiologically healthy global bone strains and moments around the mandible, and also resulted in less interfragmentary strain than less-rigid Champy fixation. Contralateral chewing exacerbated deviations in strain, moments and interfragmentary strain, especially under Champy fixation. Our pre- and post-fracture fixation findings are congruent with those from macaques, confirming that rhesus macaques are excellent animal models for biomedical research into mandibular fixation. Furthermore, these findings strengthen the case for rigid biplanar fixation over less rigid one-plate fixation in the treatment of isolated mandibular angle fractures.
Exploring jet modification via gamma-hadron and pi0-hadron correlations in AuAu collisions at PHENIX
Creators: name: Wong, Cheuk-Ping
Publisher: name: Zenodo
Year: 2022
Subjects: wwnd22
phenix
jet
photon
hadron
correlations
cnm effects
small systems
au+au
d+au
π0
elliptic
flow
p+p
3he+au
transverse momentum
p+al
p+au

description: Talk presented at the Winter Workshop on Nuclear Dynamics 2022 conference
Umbilical cord blood biomarkers of neurologic injury and the risk of cerebral palsy or infant death
Creators: name: Wapner, Ronald J.
name: O'Sullivan, Mary J.
name: Mercer, Brian M.
name: Hirtz, Deborah G.
name: Weiner, Steven J.
name: Thorp, John M.
name: Spong, Catherine Y.
name: Simhan, Hyagriv N.
name: Varner, Michael W.
name: Ramin, Susan M.
name: Sorokin, Yoram
name: Costantine, Maged M.
name: Peaceman, Alan M.
name: Rouse, Dwight J.
name: Iams, Jay D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: To evaluate the association between cerebral palsy (CP) or infant death and putative cord blood biomarkers of neurologic injury, we performed a nested case-control secondary analysis of a multicenter randomized trial of magnesium sulfate (MgSO4) versus placebo to prevent CP or death among offspring of women with anticipated delivery from 24 – 31 weeks' gestation. Cases were infants who died by 1 year (n=25) or developed CP (n=16), and were matched 1:2 to a control group (n=82) that survived without developing CP. Umbilical cord sera concentrations of S100B, neuron-specific enolase (NSE) and the total soluble form of the receptor for advanced glycation end-products (sRAGE) were measured by ELISA in duplicates. Maternal characteristics were similar between the 2 groups. Cases were born at a lower gestational age (GA) and had lower birth weight compared with controls. There were no differences in concentrations of the three biomarkers and the composite outcome of CP or infant death. However, S100B was higher (median 847.3 vs. 495.7 pg/ml; p=0.03) in infants who had CP and total sRAGE was lower (median 1259.3 vs. 1813.1 pg/ml; p=0.02) in those who died compared with the control group. When corrected for delivery GA and treatment group, both differences lost statistical significance. In conclusion, cord blood S100B level may be associated with CP, but this association was not significant after controlling for GA and MgSO4 treatment.