cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Production of verbascoside and phenolic acids in biomass of Verbena officinalis L. (vervain) cultured under different in vitro conditions
Creators: name: Paweł Kubica
name: Szopa, Agnieszka
name: Ekiert, Halina
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Plant Biology

description: Methanolic extracts from the biomass of Verbena officinalis cultured under continuous artificial light and in darkness on 12 variants of the Murashige and Skoog medium containing different concentrations (0.5–3.0 mg/L) of plant growth regulators: 6-benzyladenine, kinetin, 1-naphthaleneacetic acid and indole-3-butyric acid, were analysed for the amounts of verbascoside and phenolic acids, before and after acid hydrolysis, using the HPLC-DAD method. The amounts of verbascoside were very high (max. 2454.12 mg/100 g DW – light, and 2135.59 mg/100 g DW – darkness). The total amounts of phenolic acids reached a maximum of 46.02 mg/100 g DW (free phenolic acids) and 141.05 mg/100 g DW (bound compounds). The main metabolites were: ferulic, o-coumaric and caffeic acids. The maximum amount of verbascoside was 3.28 times higher than in extracts from the herb of the parent plant. The cultures could be proposed as a potential biotechnological source for selected biologically active compounds.
Additional file 1 of Interaction between photoperiod and variation in circadian rhythms in tomato
Creators: name: Xiang, Yanli
name: Sapir, Thomas
name: Rouillard, Pauline
name: Ferrand, Marina
name: Jiménez-Gómez, José M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Whole genome genotyping of a heterozygous line containing reduced introgressions at the positions of LNK2 and EID1. (A) The red line indicates the frequency of heterozygous SNPs in 1000-SNP windows along the 12 tomato chromosomes. (B) Zoom-in view in the chromosomal regions where the heterozygous line presented introgressions from S. pimpinellifolium. Red lines indicate the frequency of heterozygous SNPs in 100-SNP windows. The location of LNK2 and EID1 is indicated with a vertical line. The location of genes in each region is indicated with black dots along the x axis. Figure S2. Circadian parameters in the near isogenic lines generated. Three independent experiments are shown in columns and Period, Phase, Amplitude and Relative Amplitude Error in rows. The wild species S. pimpinellifolium was not included in the first experiment. Different letters in each boxplot indicate significant differences. Figure S3. Expression oscillation of LNK2 and EID1 in tomato. Data was obtained from RNA-seq data published in Müller et al 2016. Plants were grown in 12:12 light/dark and 20:18 °C temperature cycles and leaf samples collected from 7-day old seedlings every 4 hours. Read counts on each gene are normalized by gene length and sample size. Figure S4. Principal component analysis of expression values from the RNA-seq experiment in the near isogenic lines segregating for wild alleles of EID1 and LNK2. Only transcripts with more than 10 reads across all samples were included in the analysis. Figure S5. Phase and percent of differentially expressed genes among cycling genes in tomato. (a) Phase distribution of the 6017 transcripts whose expression oscillates during the diel cycle in S. lycopersicum and S. pennellii. (b) Percentage of transcripts in (a) whose expression was significantly altered by photoperiod in our experiment. Figure S6. Phylogenetic tree from protein sequence alignments for genes belonging to the LNK family in tomato and Arabidopsis. For LNK2, the sequence from the wild tomato species S. pennellii is used because of the large deletion present in this gene in cultivated tomato. Arabidopsis, cultivated tomato and S. pennellii protein names are highlighted in gray, red and green respectively. Tomato proteins whose transcript oscillates during the diel cycle are marked with an orange dot.
Additional fileÂ 5: of Feces and liver tissue metabonomics studies on the regulatory effect of aspirin eugenol eater in hyperlipidemic rats
Creators: name: Ma, Ning
name: Liu, Xiwang
name: Kong, Xiaojun
name: Li, Shihong
name: Jiao, Zenghua
name: Qin, Zhe
name: Dong, Pengcheng
name: Yang, Yajun
name: Li, Jianyong
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Virology

description: Typical UPLC-Q-TOF/MS total ion chromatograms (TICs) of liver tissue in positive and negative ion modes. (PDF 260 kb)
title: OFROM: interview avec ilcf21a13
Creators: name: Delafontaine, François
name: Keller, Jennifer
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.2466si86.v2#cfab98a9adb9b82bf39888a8b5701d4c4bcc3761
Additional fileÂ 6: of Feces and liver tissue metabonomics studies on the regulatory effect of aspirin eugenol eater in hyperlipidemic rats
Creators: name: Ma, Ning
name: Liu, Xiwang
name: Kong, Xiaojun
name: Li, Shihong
name: Jiao, Zenghua
name: Qin, Zhe
name: Dong, Pengcheng
name: Yang, Yajun
name: Li, Jianyong
Publisher: name: figshare
Year: 2017
Subjects: Medicine
Chemical Sciences not elsewhere classified
Developmental Biology
Marine Biology
Virology

description: Fragments matched in HMDB or Metlin databases in metabolites identification in liver tissue. (PDF 49 kb)
A nor-diterpene from Salvia sahendica leaves
Creators: name: Tabatabaei, Sahar Mofidi
name: Salehi, Peyman
name: Farimani, Mahdi Moridi
name: Neuburger, Markus
name: Mieri, Maria De
name: Hamburger, Matthias
name: Nejad-Ebrahimi, Samad
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Phytochemical investigation of n-hexane extract of Salvia sahendica by normal phase column chromatography resulted in the isolation of six compounds. Structures were established by 1D and 2D NMR spectroscopy, and HRMS, as a new norditerpene 1, and known terpenoids, sclareol (2), oleanolic acid (3), β-sitosterol (4), salvigenin (5) and 3α-hydroxy-11α,12α-epoxyoleanan-28,13β-olide (6). The absolute configuration of 1 was confirmed by a combination of X-ray single crystal analysis and electronic circular dichroism spectroscopy. In vitro cytotoxic activity on breast cancer cell line (MDA-MB-231) and also the antimicrobial activity of the pure compounds were tested against Staphylococcus aureus, Bacilus cereus and Escherichia coli.
Additional fileÂ 7: of Feces and liver tissue metabonomics studies on the regulatory effect of aspirin eugenol eater in hyperlipidemic rats
Creators: name: Ma, Ning
name: Liu, Xiwang
name: Kong, Xiaojun
name: Li, Shihong
name: Jiao, Zenghua
name: Qin, Zhe
name: Dong, Pengcheng
name: Yang, Yajun
name: Li, Jianyong
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Typical UPLC-Q-TOF/MS total ion chromatograms (TICs) of feces in positive and negative ion modes. (PDF 242 kb)
Opacity in agreement
Creators: name: Kalin, Laura
Publisher: name: Zenodo
Year: 2019

description: In this paper, I use a complex pattern of agreement in progressives in the Neo-
 Aramaic language Senaya as a window into the timing of and relationship among
 the different components of φ-agreement. In particular, I argue that we need to
 recognize three distinct, ordered operations underlying what we see on the surface
 as φ-agreement – Match, Value, and Vocabulary Insertion – based on data that
 reveal that opacity can arise both in the relation between Match and Value, as
 well as in the relation between Value and Vocabulary Insertion. This work builds
 on and extends earlier research that recognizes the need for (at least a subset of)
 these distinct components, including (among many others) Halle & Marantz (1993;
 1994), Béjar (2003), Arregi & Nevins (2012), Bhatt & Walkow (2013), Bonet (2013),
 and Marušič et al. (2015).
Additional file 1 of Alcohol consumption and closed borders - how COVID-19 restrictions have impacted alcohol sales and consumption in Europe
Creators: name: Leifman, Håkan
name: Dramstad, Kalle
name: Juslin, Emil
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
The extraction and characterisation of a polysaccharide from Moniliophthora perniciosa CCMB 0257
Creators: name: Gildomar L. Valasques Junior
name: Elisangela F. Boffo
name: Jener David G. Santos
name: Brandão, Hugo Neves
name: Mascarenhas, Artur J. S.
name: Cruz, Fernanda T.
name: Assis, Sandra A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: The alpha-D-glucans are worldwide acknowledged as powerful immune system stimulants found in several sources; however, the fungal-derived sources appear to respond with higher activity. The present study has investigated polysaccharide production in Moniliophthora perniciosa. The dry biomass was subjected to thermal treatment in alkaline solution after fermentation. The biopolymers dissolved in this solution were precipitated after three volumes of absolute ethanol were added to the supernatant. The pure polysaccharide MPS1 was obtained through molecular exclusion chromatography using the Sephacryl S-200 column. The HPLC-RI analysis showed that MPS1 was a glucose homopolysaccharide. Nuclear magnetic resonance (NMR) spectra indicated the α-form as the anomeric carbon configuration in glucose residue. The structure of the polysaccharide was further confirmed as (1→4)-α-D-glucan through the chemical shift of C4. The molecular weight of MPS1 was 31.0 kDa.
Additional file 2 of SETMAR, a case of primate co-opted genes: towards new perspectives
Creators: name: Lié, Oriane
name: Renault, Sylvaine
name: Augé-Gouillou, Corinne
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2: Table S2. Gene ontology of SETMAR and brain co-regulated genes during embryogenesis.
Secondary metabolites from the endophytic fungus Talaromyces pinophilus
Creators: name: F. Vinale
name: R. Nicoletti
name: F. Lacatena
name: R. Marra
name: A. Sacco
name: N. Lombardi
name: G. D’Errico
name: M. C. Digilio
name: M. Lorito
name: S. L. Woo
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Endophytic fungi have a great influence on plant health and growth, and are an important source of bioactive natural compounds. Organic extracts obtained from the culture filtrate of an endophytic strain of Talaromyces pinophilus isolated from strawberry tree (Arbutus unedo) were studied. Metabolomic analysis revealed the presence of three bioactive metabolites, the siderophore ferrirubin, the platelet-aggregation inhibitor herquline B and the antibiotic 3-O-methylfunicone. The latter was the major metabolite produced by this strain and displayed toxic effects against the pea aphid Acyrthosiphon pisum (Homoptera Aphidiidae). This toxicity represents an additional indication that the widespread endophytic occurrence of T. pinophilus may be related to a possible role in defensive mutualism. Moreover, the toxic activity on aphids could promote further study on 3-O-methylfunicone, or its derivatives, as an alternative to synthetic chemicals in agriculture.
Distributed agreement in participial sandwiched configurations
Creators: name: Marušič, Franc Lanko
name: Nevins, Andrew
Publisher: name: Zenodo
Year: 2019

description: In recent years, several proposals have appeared that try to model the patterns
 of agreement with coordinate noun phrases found in South Slavic Languages. We
 investigate agreement in so-called sandwiched configurations, whereby a coordi-
 nated noun phrase sits between two agreeing participles. In such cases, the two
 participles do not necessarily agree with each other, given a scenario in which the
 first and the second conjunct have different phi-features. This means the two par-
 ticiples choose their target of agreement independently. We argue the results of
 our experimental study favor an approach to agreement that places it partially in
 PF.
Additional fileÂ 8: of Feces and liver tissue metabonomics studies on the regulatory effect of aspirin eugenol eater in hyperlipidemic rats
Creators: name: Ma, Ning
name: Liu, Xiwang
name: Kong, Xiaojun
name: Li, Shihong
name: Jiao, Zenghua
name: Qin, Zhe
name: Dong, Pengcheng
name: Yang, Yajun
name: Li, Jianyong
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy
subject: Virology

description: Fragments matched in HMDB or Metlin databases in metabolites identification in feces. (PDF 52 kb)
Stable isotope mass balances versus concentration differences of dissolved inorganic carbon – implications for tracing carbon turnover in reservoirs
Creators: name: Barth, Johannes A. C.
name: Mader, Michael
name: Nenning, Franziska
name: Geldern, Robert Van
name: Friese, Kurt
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: The aim of this study was to identify sources of carbon turnover using stable isotope mass balances. For this purpose, two pre-reservoirs in the Harz Mountains (Germany) were investigated for their dissolved and particulate carbon contents (dissolved inorganic carbon (DIC), dissolved organic carbon, particulate organic carbon) together with their stable carbon isotope ratios. DIC concentration depth profiles from March 2012 had an average of 0.33 mmol L–1. Increases in DIC concentrations later on in the year often corresponded with decreases in its carbon isotope composition (δ13CDIC) with the most negative value of –18.4 ‰ in September. This led to a carbon isotope mass balance with carbon isotope inputs of −28.5 ‰ from DOC and −23.4, −31.8 and −30.7 ‰ from algae, terrestrial and sedimentary matter, respectively. Best matches between calculated and measured DIC gains were achieved when using the isotope composition of algae. This shows that this type of organic material is most likely responsible for carbon additions to the DIC pool when its concentrations and δ13CDIC values correlate negatively. The presented isotope mass balance is transferable to other surface water and groundwater systems for quantification of organic matter turnover.
Comparative analytical study of the selected wine varieties grown in Montenegro
Creators: name: Đorđević, Neda O.
name: Novaković, Miroslav M.
name: Pejin, Boris
name: Mutić, Jelena J.
name: Vajs, Vlatka E.
name: Snežana B. Pajović
name: Vele V. Tešević
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010–2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R = 0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65 mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products.
title: OFROM: interview avec ilcf21a12
Creators: name: Delafontaine, François
name: Keller, Jennifer
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.3e48rkbn.v2#70067206421999a2d2df4b886cff52df72fbcb43
Cytotoxicity of flavonoids and isoflavonoids from Crotalaria bracteata
Creators: name: Sukanda Sudanich
name: Suppachai Tiyaworanant
name: Chavi Yenjai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Plant Biology

description: A new flavonoid, crotakanda (1), and seven known compounds including a flavonoid, four isoflavonoids, a pterocarpan and a cinnamaldehyde were isolated from the stems and roots of Crotalaria bracteata. Their structures were elucidated by a combination of spectroscopic methods. Compound 2 showed cytotoxicity against MCF-7 with an IC50 value of 79.90 μM whereas 2 and 4 exhibited cytotoxicity against the NCI-H187 cell line with IC50 values of 71.57 and 95.47 μM, respectively.
Additional file 3 of SETMAR, a case of primate co-opted genes: towards new perspectives
Creators: name: Lié, Oriane
name: Renault, Sylvaine
name: Augé-Gouillou, Corinne
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3: Supp Data. Mat & Met for SETMAR and cognition.
Prof. Dr. Dario Cebic ANALYSE Claude Debussy - Ausgewählte Werke für Klavier II ,,Danseus de Delphes"
Creators: name: Prof.Dr. Dario Cebic
Publisher: name: Zenodo
Year: 2020
Subjects: Debussy, Danseus de Delphes

description: At the beginning of the piece we find a counterpoint with 3 different ideas: 1 chromatic/semitone (b - h - c - cis) 2 semitone + whole tone steps (f - g - a) 3 semitone + major third (b - a - f) Takt (bars) 21-24 Debussy combines melody (octave chordal harmonies) and syncopated quintoctave sounds into a series of constant paraphrase major chords. It's about a polytonal mixture.
Additional fileÂ 9: of Feces and liver tissue metabonomics studies on the regulatory effect of aspirin eugenol eater in hyperlipidemic rats
Creators: name: Ma, Ning
name: Liu, Xiwang
name: Kong, Xiaojun
name: Li, Shihong
name: Jiao, Zenghua
name: Qin, Zhe
name: Dong, Pengcheng
name: Yang, Yajun
name: Li, Jianyong
Publisher: name: figshare
Year: 2017
Subjects: Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Pathway analysis result with MetaboAnalyst 3.0. (PDF 43 kb)
Two new lignans from Saururus chinensis
Creators: name: Cuibai Li
name: Ningxin Li
name: Jiarui Yue
name: Qishi Song
name: Qingfei Fan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Plant Biology

description: Two new lignans, (Z)-14-bis(3′,4′-dimethoxyphenyl)-2,3-dimethylbut-2-ene-1,4-dione (1), threo-2-methyl-3-oxo-1-(3′,4′,5′-trimethoxyphenyl)butyl-3″,4″-dimethoxybenzoate (2), together with 15 known derivatives (3–17) were isolated from Saururus chinensis. Their structures were determined on the basis of spectral data, including 1D and 2D NMR experiments and HREIMS spectra. The antitumour activity was screened by MTT assay, compounds 1, 2, 3, 5, 9–11 and 13–15 showed no cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7 and SW480 cell lines.
Clinical disposition, metabolism and in vitro drug–drug interaction properties of omadacycline
Creators: name: Flarakos, Jimmy
name: Du, Yancy
name: Gu, Helen
name: Wang, Lai
name: J. Einolf, Heidi
name: Chun, Dung Y.
name: Zhu, Bing
name: Alexander, Natalia
name: Natrillo, Adrienne
name: Hanna, Imad
name: Ting, Lillian
name: Zhou, Wei
name: Dole, Kiran
name: Sun, Haiying
name: Kovacs, Steven J.
name: Stein, Daniel S.
name: Tanaka, S. Ken
name: Villano, Stephen
name: B. Mangold, James
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: 1. Absorption, distribution, metabolism, transport and elimination properties of omadacycline, an aminomethylcycline antibiotic, were investigated in vitro and in a study in healthy male subjects. 2. Omadacycline was metabolically stable in human liver microsomes and hepatocytes and did not inhibit or induce any of the nine cytochrome P450 or five transporters tested. Omadacycline was a substrate of P-glycoprotein, but not of the other transporters. 3. Omadacycline metabolic stability was confirmed in six healthy male subjects who received a single 300 mg oral dose of [14C]-omadacycline (36.6 μCi). Absorption was rapid with peak radioactivity (∼610 ngEq/mL) between 1–4 h in plasma or blood. The AUClast of plasma radioactivity (only quantifiable to 8 h due to low radioactivity) was 3096 ngEq h/mL and apparent terminal half-life was 11.1 h. Unchanged omadacycline reached peak plasma concentrations (∼563 ng/mL) between 1–4 h. Apparent plasma half-life was 17.6 h with biphasic elimination. Plasma exposure (AUCinf) averaged 9418 ng h/mL, with high clearance (CL/F, 32.8 L/h) and volume of distribution (Vz/F 828 L). No plasma metabolites were observed. 4. Radioactivity recovery of the administered dose in excreta was complete (>95%); renal and fecal elimination were 14.4% and 81.1%, respectively. No metabolites were observed in urine or feces, only the omadacycline C4-epimer.
title: OFROM: interview avec ilcf21a11
Creators: name: Delafontaine, François
name: Keller, Jennifer
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.23fakd65.v2#6ff2680440e13b86ab7a677ba63b852bb5cebacb
NMR data of methylated products from In vitro evaluation of the effect of C-4 substitution on methylation of 7,8-dihydroxycoumarin: metabolic profile and catalytic kinetics.
Creators: name: Xia, Yang-Liu
name: Dou, Tong-Yi
name: Liu, Yong
name: Wang, Ping
name: Ge, Guang-Bo
name: Yang, Ling
Publisher: name: The Royal Society
Year: 2018

description: Chemical shift and spectra of 1H NMR and 13C NMR for 7-O- and 8-O-methyl conjugates of daphnetin, 4-MDPN, 4-PDPN and 4-ADPN.
NMR data of methylated products from In vitro evaluation of the effect of C-4 substitution on methylation of 7,8-dihydroxycoumarin: metabolic profile and catalytic kinetics
Creators: name: Xia, Yang-Liu
name: Dou, Tong-Yi
name: Liu, Yong
name: Wang, Ping
name: Ge, Guang-Bo
name: Yang, Ling
Publisher: name: The Royal Society
Year: 2017

description: Chemical shift and spectra of 1H NMR and 13C NMR for 7-O- and 8-O-methyl conjugates of daphnetin, 4-MDPN, 4-PDPN and 4-ADPN.
title: OFROM: interview avec ilcf21a10
Creators: name: Delafontaine, François
name: Keller, Jennifer
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.8a0142k9.v2#77fd60d1f81093422632aa3028f60c0e1bf82315
PROGRAMAS DE GERENCIAMENTO DE ESTRESSE UTILIZADOS PARA TRATAMENTO DE ENFERMEIROS COM BURNOUT: Uma revisão de escopo
Creators: name: Lilian Braga do Nascimento
name: Gabriela Granja Porto Petraki
name: Renata de Albuquerque Cavalcanti Almeida
name: Isabella Maria da Silva Lemos
name: Katyane Tabosa Mendes da Silva
name: Ana Claudia Amorim Gomes Dourado
name: Adriana Conrado de Almeida
name: José Rodrigues Laureano Filho
Publisher: name: Zenodo
Year: 2023

description: RESUMO:

A exaustão é a qualidade central do esgotamento que reflete uma dimensão do estresse. O burnout é uma síndrome que envolve atitudes e condutas negativas com os usuários, clientes, organização e trabalho. As atividades específicas da enfermagem propiciam essa condição que pode causar sofrimento e adoecimento. Objetivo: Realizar um mapeamento da literatura, quanto às evidências disponíveis sobre programas de gerenciamento de estresse utilizados para tratamento de enfermeiros com burnout. Método: Trata-se de uma Revisão de escopo. A pesquisa foi registrada no OSF- open Science Framework (OSF é um projeto de software gratuito e de código aberto que facilita a colaboração em pesquisas científicas). Foram realizadas buscas utilizando descritores controlados e palavras chaves nas seguintes bases de dados: MEDLINE (PubMed), Embase, CINAHL, PsycINFO, LILACS, SCOPUS, Web of Science e Cochrane. Foram selecionados 19 artigos (publicados entre 2010 e 2023), nos quais foram identificados  os principais programas de gerenciamento de estresse utilizados para o tratamento de enfermeiros com burnout. Resultado: Na pesquisa realizada em 30/06/2023, nas bases de dados selecionadas, foram encontrados 10.793 artigos (com duplicatas) e com datas de publicação entre 2010 e 2023. Após remover duplicatas, restaram 3.540 artigos. Desses registros, foram selecionados 55 artigos que atendiam aos critérios de elegibilidade após a leitura dos títulos e resumos. Em seguida, após leitura na íntegra, 36 estudos foram excluídos porque não são relevantes para o objetivo da análise do escopo. Conclusão:As análises feitas nos estudos não apresentou conclusão definitiva para o tratamento do burnout em enfermeiros, porém o mindfulness foi a terapia mais estudada nos traballhos encontrados e parece ser a mais eficiente. Estudos primários futuros precisam utilizar técnicas de redução de burnout comparando enfermeiros que trabalhem no mesmo setor,no mesmo turno de trabalho ecom mesmo nível de estresse.

 

DESCRITORES: Enfermagem. Unidade de saúde. Esgotamento Psicológico. Estresse Ocupacional.
Chemical profiling and biological properties of Neolitsea kedahense Gamble essential oils
Creators: name: Nor Akmalazura Jani
name: Hasnah Mohd Sirat
name: Farediah Ahmad
name: Nor Azah Mohamad Ali
name: Mailina Jamil
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Hydrodistillation of the fresh stem and leaf of Neolitsea kedahense Gamble, collected from Gunung Jerai, Malaysia followed by the GC-FID and GC-MS analysis revealed the detection of a total of 47 constituents of which 28 (86.4%) from the stem and 31 (96.4%) constituents from the leaf. δ-Cadinene (17.4%), 1-epi-cubenol (11.8%), cyperotundone (9.0%), cis-cadin-4-en-7-ol (7.7%), τ-cadinol (7.1%) and α-cadinol (7.1%) were the principle constituents in the stem oil, whereas β-caryophyllene (18.9%), bicyclogermacrene (18.6%) and trans-muurola-4(14),5-diene (9.8%) were the major constituents in the leaf oil. Among the identified constituents, three constituents namely 7-epi-α-selinene, junenol and cis-cadin-4-en-7-ol have not been found previously from Neolitsea oils. The stem and leaf oils were screened for their α-glucosidase inhibitory and antibacterial activities. Both oils displayed potential α-glucosidase inhibitory activity, while the stem oil possessed weak antibacterial activity against Bacillus subtilis.
Long distance agreement and information structure
Creators: name: Mursell, Johannes
Publisher: name: Zenodo
Year: 2019

description: In this paper, I discuss a specific subtype of long distance agreement (LDA), namely
 agreement across a finite (CP) clause boundary. I show that most, if not all, in-
 stances of LDA depend on information-structural properties of the agreement tar-
 get in the embedded clause, be it for cross clausal object agreement or case assign-
 ment. After discussing LDA in unrelated language families, I argue that LDA is pos-
 sible due to a complex probe in the left periphery containing information-structural
 features bundled with φ-features. This probe serves as an intermediate agreement
 step between a verb in the matrix clause and the information-structurally marked
 element in the embedded clause, so that LDA does not violate the phase impene-
 trability condition.
Additional file 1 of Prevalence of porcine parvovirus 1 through 7 (PPV1-PPV7) and co-factor association with PCV2 and PRRSV in Korea
Creators: name: Kim, Seung-Chai
name: Kim, Jae-Hong
name: Kim, Jae-Yeob
name: Park, Gyeong-Seo
name: Jeong, Chang-Gi
name: Kim, Won-Il
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplementary Figure 1. Percentage of porcine parvoviruses 1-7 (PPV1-PPV7) positive samples from piglets, weaners, fatteners and sow or gilts in different diagnostic materials (serum, lungs and feces).
Evaluation of antioxidant and tyrosinase inhibitory activities of the extracts of Sarcopoterium spinosum (L.) Spach fruits
Creators: name: Piras, Alessandra
name: Era, Benedetta
name: Petrillo, Amalia Di
name: Paramás, Ana María González
name: Maxia, Andrea
name: Maccioni, Alfredo
name: Porcedda, Silvia
name: Falconieri, Danilo
name: Rosa, Antonella
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology

description: Sarcopoterium spinosum fruits have been used to get extracts of different nature; two fixed oils were obtained by means of supercritical fluid extraction (SFE) with CO2 at 250 bar and 40°C and using n-hexane in a Soxhlet extraction (SE) apparatus. Aqueous solutions: an aromatic water (AW) and a residual water (RW) were obtained by hydrodistillation (HD). In the RW, following have been identified: quercetin glucuronide, luteolin 7-O-glucuronide, isorhamnetin 3-O-glucuronide, quercetin sulfate and quercetin. Among all tested plant extracts, the RW had the highest content of polyphenol (378 mg GAE/g of weight) and of flavonoids (26 mg QE/g of weight), and the highest antioxidant activity, comparable to that of Trolox. It was also the most active extract of this series (IC50 = 0.292 mg/mL) in the tyrosinase activity assays performed with L-3,4-dihydroxyphenylalanine (L-DOPA) as substrate.
title: 01_1464
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Chemical composition of Ivorian Artabotrys insignis leaf oil. Combined analysis including 13C NMR, to quantify germacrene A and β-elemene
Creators: name: Gooré, Stéphane G.
name: Ouattara, Zana A.
name: Yapi, Thierry A.
name: Yves-Alain Békro
name: Tomi, Pierre
name: Paoli, Mathieu
name: Tomi, Félix
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry

description: The chemical composition of leaf essential oil from Artabotrys insignis Engler & Diels collected from Cote d’Ivoire was determined by GC(FID), GC-MS and 13C NMR. The main compounds were β-elemene (66.8%) and germacrene A (17.1%). The true content of germacrene A/β-elemene was obtained by combining GC(FID) and 13C NMR data.
ESM.pdf from Dynamics and locomotion of flexible foils in a frictional environment.
Creators: name: Wang, Xiaolin
name: Alben, Silas
Publisher: name: The Royal Society
Year: 2018

description: Over the past few decades, oscillating flexible foils have been used to study the physics of organismal propulsion in different fluid environments. Here, we extend this work to a study of flexible foils in a frictional environment. When the foil is oscillated by heaving at one end but is not free to locomote, the dynamics change from periodic to non-periodic and chaotic as the heaving amplitude increases or the bending rigidity decreases. For friction coefficients lying in a certain range, the transition passes through a sequence of N-periodic and asymmetric states before reaching chaotic dynamics. Resonant peaks are damped and shifted by friction and large heaving amplitudes, leading to bistable states. When the foil is free to locomote, the horizontal motion smoothes the resonant behaviours. For moderate frictional coefficients, steady but slow locomotion is obtained. For large transverse friction and small tangential friction corresponding to wheeled snake robots, faster locomotion is obtained. Travelling wave motions arise spontaneously, and move with horizontal speeds that scale as transverse friction coefficient to the coefficient to and input power that scales as the transverse friction coefficient to the power 5/12. These scalings are consistent with a boundary layer form of the solutions near the foil's leading edge.
Additional file 1 of Socioeconomic and geographic differences in ablation of atrial fibrillation in Norway - a national cohort study
Creators: name: Olsen, Frank
name: Uleberg, Bård
name: Jacobsen, Bjarne K.
name: Heuch, Ivar
name: Tande, Pål M.
name: Bugge, Einar
name: Balteskard, Lise
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1 Supplementary tables.
ESM.pdf from Dynamics and locomotion of flexible foils in a frictional environment
Creators: name: Wang, Xiaolin
name: Alben, Silas
Publisher: name: The Royal Society
Year: 2017

description: Over the past few decades, oscillating flexible foils have been used to study the physics of organismal propulsion in different fluid environments. Here, we extend this work to a study of flexible foils in a frictional environment. When the foil is oscillated by heaving at one end but is not free to locomote, the dynamics change from periodic to non-periodic and chaotic as the heaving amplitude increases or the bending rigidity decreases. For friction coefficients lying in a certain range, the transition passes through a sequence of N-periodic and asymmetric states before reaching chaotic dynamics. Resonant peaks are damped and shifted by friction and large heaving amplitudes, leading to bistable states. When the foil is free to locomote, the horizontal motion smoothes the resonant behaviours. For moderate frictional coefficients, steady but slow locomotion is obtained. For large transverse friction and small tangential friction corresponding to wheeled snake robots, faster locomotion is obtained. Travelling wave motions arise spontaneously, and move with horizontal speed that scales as transverse friction to the 1/4 power and input power that scales as transverse friction to the 5/12 power. These scalings are consistent with a boundary layer form of the solutions near the foil's leading edge.
Fragrance components of Platanthera bifolia subsp. osca
Creators: name: D’Auria, Maurizio
name: Lorenz, Richard
name: Racioppi, Rocco
name: Romano, Vito Antonio
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: SPME-GC-MS analysis of the scent of Platanthera bifolia subsp. osca collected during the night showed as main components lilac alcohols B, C and D and lilac aldehydes A, B and C. Other significant chemical components were linalool and caryophyllene. Some differences were found in comparison with previously reported analyses of the scent of P. bifolia and Platanthera chlorantha. The most important difference found was in the composition of the ester fraction.
Supporting files for Jedličková et al, 2024 "Genome editing in almond: A CRISPR-based approach through hairy root transformation"
Creators: name: Robert, Helene
name: Jedličková, Veronika
Publisher: name: Zenodo
Year: 2024

description: Supporting files for Jedličková et al, 2024 comprising ab1 files of CRISPR-edited sequences of ERF47 and GAI in Prunus dulcis for:

ERF74, E-CP1 at the locus targeted by gRNA2, in hairy root 1

ERF74, E-CP6 at the locus targeted by gRNA2, in hairy root 1

ERF74, E-CP6 at the locus targeted by gRNA2, in hairy root 2

GAI, G-CP4 at the locus targeted by gRNA2, in hairy root 1

GAI, G-CP5 at the locus targeted by gRNA2, in hairy root 1 from PCR product cloned in pGEM-T, colony 1

GAI, G-CP5 at the locus targeted by gRNA2, in hairy root 1 from PCR product cloned in pGEM-T, colony 2

sequences of the regions containing the guide RNAs in Vairo cultivar

CP, composite plant
Additional file 1 of Muscle histological changes in a large cohort of patients affected with Becker muscular dystrophy
Creators: name: Ripolone, Michela
name: Velardo, Daniele
name: Mondello, Stefania
name: Zanotti, Simona
name: Magri, Francesca
name: Minuti, Elisa
name: Cazzaniga, Sara
name: Fortunato, Francesco
name: Ciscato, Patrizia
name: Tiberio, Francesca
name: Sciacco, Monica
name: Moggio, Maurizio
name: Bettica, Paolo
name: Comi, Giacomo P.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 60506 Virology

description: Additional file 1 Western Blot Analysis
Biogenic guaianolide-type sesquiterpene lactones with antioxidative and anti-inflammatory properties from natural mangrove hybrid Rhizophora annamalayana
Creators: name: Vamshi Krishna Raola
name: Chakraborty, Kajal
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Previously undescribed guaianolide-type sesquiterpene lactones were isolated from the chloroform fraction of the natural hybrid mangrove Rhizophora annamalayana, and were characterised as (Z)-3α,4,5,6-tetrahydro-5α-isobutyl-2β-(methoxymethyl)-7-methyl-3H-cyclohepta[b]carbolactone (1) and (7Z)-isopentyl 3α,4,5,6,7,8-hexahydro-2β-((E)-11-methylbut-10-enyl)-1-oxo-2H-cyclohepta[b]furan-6-carboxylate (2). Compound 2 displayed greater antioxidative activities {1, 1-diphenyl-2-picrylhydrazyl (DPPH) and 2, 2′-azino-bis-3 ethylbenzothiozoline-6-sulphonic acid diammonium salt (ABTS), IC50 0.65 and 0.62 mg/mL, respectively)} compared to 1 (IC50 0.83 and 1.14 mg/mL, respectively) (p 2 recorded no significant difference in DPPH. scavenging activities (IC50 0.65 mg/mL) compared to α-tocopherol (IC50 0.63 mg/mL). Pro-inflammatory 5-lipoxygenase inhibitory activity of 2 was found to be comparable (IC50 0.98 mg/mL) to that displayed by synthetic anti-inflammatory drug ibuprofen (IC50 0.93 mg/mL). Compound 2 showed significantly greater selectivity index (anti-cyclooxygenase-1/anti-cyclooxygenase-2 = 2.15) than non-steroidal anti-inflammatory ibuprofen (<0.5) (p
MOESM1 of MKRMDA: multiple kernel learning-based Kronecker regularized least squares for MiRNAâ disease association prediction
Creators: name: Chen, Xing
name: Niu, Ya-Wei
name: Wang, Guang-Hui
name: Yan, Gui-Ying
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Additional file 1. Additional information about the multiple kernel learning method, two-step optimization process and the case studies comparison with HGIMDA and RKNNMDA.