cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Development of a pediatric differentiated thyroid carcinoma registry within the EuRRECa project : rationale and protocol hS. C. Clement, K. Lorenz [und viele weitere]
Creators: name: Clement, S. C.
name: Lorenz, K.
name: [Und Viele Weitere]
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 618

description: Background: Although differentiated thyroid carcinoma (DTC) is the most frequent endocrine pediatric cancer, it is rare in childhood and adolescence. While tumor persistence and recurrence are not uncommon, mortality remains extremely low. Complications of treatment are however reported in up to 48% of the survivors. Due to the rarity of the disease, current treatment guidelines are predominantly based on the results of small observational retrospective studies and extrapolations from results in adult patients. In order to develop more personalized treatment and follow-up strategies (aiming to reduce complication rates), there is an unmet need for uniform international prospective data collection and clinical trials. Methods and analysis: The European pediatric thyroid carcinoma registry aims to collect clinical data for all patients ≤18 years of age with a confirmed diagnosis of DTC who have been diagnosed, assessed, or treated at a participating site. This registry will be a component of the wider European Registries for Rare Endocrine Conditions project which has close links to Endo-ERN, the European Reference Network for Rare Endocrine Conditions. A multidisciplinary expert working group was formed to develop a minimal dataset comprising information regarding demographic data, diagnosis, treatment, and outcome. We constructed an umbrella-type registry, with a detailed basic dataset. In the future, this may provide the opportunity for research teams to integrate clinical research questions.
Microphase separation in nonequilibrium biomembranes
Creators: name: Sens, Pierre
name: Turner, Matthew S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Subcellular Processes (q-bio.SC)
subject: FOS: Biological sciences

description: Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be driven by fluctuating forces. We show that the membrane steady state is not only controlled by the strength of the forces and how they couple to the membrane, but also by their dynamics: In a simple class of models this is captured by a single a correlation time. We conclude that the coupling of membrane composition to normal mechanical forces, such as might be exerted by polymerizing cytoskeleton filaments, could play an important role in controlling the steady state of a cell membrane that exhibits transient microphase separation on lengthscales in the 10-100 nm regime.
title: ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐµÐ¿Ð°ÑÐ°ÑÐ¸Ð¸ Ð·Ð°ÑÑÐ¶ÐµÐ½Ð½ÑÑ ÑÐ°ÑÑÐ¸Ñ Ð¿ÑÐ¸ Ð°ÑÐ¼Ð¾ÑÑÐµÑÐ½Ð¾Ð¼ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Investigation of a particle separation system at atmospheric pressure
Creators: name: ÐÐ¸Ð»ÑÐ´Ð°Ð½Ð¾Ð², ÐÐ°Ð¹ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: Ð¸Ð¾Ð½Ð¸Ð·Ð°ÑÐ¸Ñ
Ð¸Ð¾Ð½-Ð´ÑÐµÐ¹ÑÐ¾Ð²Ð°Ñ ÑÐ¿ÐµÐºÑÑÐ¾Ð¼ÐµÑÑÐ¸Ñ
ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð·Ð°ÑÐ²Ð¾ÑÑ
ÑÐ¿ÐµÐºÑÑÐ¾-Ð¼ÐµÑÑÐ¸Ñ Ð¸Ð¾Ð½Ð½Ð¾Ð¹ Ð¿Ð¾Ð´Ð²Ð¸Ð¶Ð½Ð¾ÑÑÐ¸
ionization
ion-drift spectrometry
electric gates
ion mobility spectrometry

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐµÐ¿Ð°ÑÐ°ÑÐ¸Ð¸ Ð¿Ð¾ÑÐ¾ÐºÐ° Ð·Ð°ÑÑÐ¶ÐµÐ½Ð½ÑÑ ÑÐ°ÑÑÐ¸Ñ, Ð² ÑÐ°ÑÑÐ½Ð¾ÑÑÐ¸, Ð¿ÑÐ¸Ð¼ÐµÐ½ÑÐµÐ¼ÑÐµ Ð² ÑÐ¾ÑÑÐ°Ð²Ðµ Ð¸Ð¾Ð½-Ð´ÑÐµÐ¹ÑÐ¾Ð²ÑÑ ÑÐ¿ÐµÐºÑÑÐ¾Ð¼ÐµÑÑÐ¾Ð². ÐÑÐ¸Ð±Ð¾ÑÑ, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ñ Ð½Ð° Ð¼ÐµÑÐ¾Ð´Ðµ ÑÐ¿ÐµÐºÑÑÐ¾Ð¼ÐµÑÑÐ¸Ð¸ Ð¸Ð¾Ð½Ð½Ð¾Ð¹ Ð¿Ð¾Ð´Ð²Ð¸Ð¶Ð½Ð¾ÑÑÐ¸, ÑÑÐ¿ÐµÑÐ½Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÑÑÑÑÑ Ð² ÑÑÐµÑÐµ Ð¼ÐµÐ´Ð¸ÑÐ¸Ð½ÑÐºÐ¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð°, ÑÐ°ÑÐ¼Ð°ÑÐµÐ²ÑÐ¸ÐºÐ¸, ÑÐ¾ÐºÑÐ¸ÐºÐ¾Ð»Ð¾Ð³Ð¸Ð¸, ÑÐ»ÐµÐ´Ð¾Ð²Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð´Ð¾Ð¿Ð¸Ð½Ð³Ð°, Ð½Ð°ÑÐºÐ¾ÑÐ¸ÐºÐ¾Ð².
description: The given work is devoted to study the characteristics of the charged particle flow separation system, in particular, those used in iondrift spectrometers. Devices based on the method of ionic mobility spectrometry are successfully used in the field of medical analysis, pharmaceuticals, toxicology, and trace analysis of doping, drugs.
A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases
Creators: name: Bernhardt, Alexander
name: Tiedt, Steffen
name: Teupser, Daniel
name: Dichgans, Martin
name: Meyer, Bernhard
name: Gempt, Jens
name: Kuhn, Peer-Hendrik
name: Simons, Mikael
name: Palleis, Carla Teresa
name: Weidinger, Endy
name: Nübling, Georg
name: Holdt, Lesca Miriam
name: Hönikl, Lisa
name: Gasperi, Christiane
name: Giesbertz, Pieter
name: Müller, Stephan Andreas
name: Breimann, Stephan
name: Lichtenthaler, Stefan
name: Kuster, Bernhard
name: Mann, Matthias
name: Imhof, Axel
name: Barth, Teresa
name: Hauck, Stefanie M.
name: Zetterberg, Henrik
name: Otto, Markus
name: Weichert, Wilko
name: Hemmer, Bernhard
name: Levin, Johannes Martin
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: A major evolution from purely clinical diagnoses to biomarker supported clinical diagnosing has been occurring over the past years in neurology. High-throughput methods, such as next-generation sequencing and mass spectrometry-based proteomics along with improved neuroimaging methods, are accelerating this development. This calls for a consensus framework that is broadly applicable and provides a spot-on overview of the clinical validity of novel biomarkers. We propose a harmonized terminology and a uniform concept that stratifies biomarkers according to clinical context of use and evidence levels, adapted from existing frameworks in oncology with a strong focus on (epi)genetic markers and treatment context. We demonstrate that this framework allows for a consistent assessment of clinical validity across disease entities and that sufficient evidence for many clinical applications of protein biomarkers is lacking. Our framework may help to identify promising biomarker candidates and classify their applications by clinical context, aiming for routine clinical use of (protein) biomarkers in neurology.
Additional file 5 of Unveiling the long non-coding RNA profile of porcine reproductive and respiratory syndrome virus-infected porcine alveolar macrophages
Creators: name: Gao, Junxin
name: Pan, Yu
name: Xu, Yunfei
name: Zhang, Wenli
name: Zhang, Lin
name: Li, Xi
name: Tian, Zhijun
name: Chen, Hongyan
name: Wang, Yue
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 5.
Visceral to subcutaneous fat ratio predicts short-term mortality in patients with Covid 19 : a multicenter study
Creators: name: Surov, Alexey
name: Thormann, Maximilian
name: Kardas, Hakan
name: Hinnerichs, Mattes
name: Omari, Jazan
name: Cingöz, Eda
name: Dursun, Memduh
name: Kormaz, İnan
name: Orhan, Çağrı
name: Yildiz, Ömer
name: Hocaoğlu, Elif
name: Inci, Ercan
name: Önder, Hakan
name: Erk, Hamdullah
name: Chousein, Ougkour
name: Sasani, Hadi
name: Gönen, Korcan Aysun
name: Pech, Maciej
name: Wienke, Andreas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Objective: To evaluate the association of body composition parameters with outcomes in Covid-19. Methods: 173 patients hospitalized for Covid-19 infection in 6 European centers were included in this retrospective study. Measurements were performed at L3-level and comprised skeletal muscle index (SMI), muscle density (MD), and adipose tissue measurements [visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intramuscular adipose tissue (IMAT), visceral-to-subcutaneous-adipose-tissue-area-ratio (VSR)]. The association with mortality, the need for intubation (MV), and the need for admission to ICU within 30 days were evaluated. Results: Higher SAT density was associated with a greater risk of MV (OR = 1.071, 95%CI=(1.034;1.110), p < 0.001). Higher VAT density was associated with admission to ICU (OR = 1.068, 95%CI=(1.029;1.109), p < 0.001). Higher MD was a protective factor for MV and ICU admission (OR = 0.914, 95%CI=(0.870;0.960), p < 0.001; OR = 0.882, 95%CI=(0.832;0.934), p = 0.028). Higher VSR was associated with mortality (OR = 2.147, 95%CI=(1.022;4.512), p = 0.044). Male sex showed the strongest influence on the risk of ICU admission and MV. SMI was not associated with either parameter. Conclusion: In patients hospitalized for Covid-19 infection, higher VSR seems to be a strong prognostic factor of short-term mortality. Weak associations with clinical course were found for MD and adipose tissue measurements. Male sex was the strongest prognostic factor of adverse clinical course.
Sieve-based confidence intervals and bands for Lévy densities
Creators: name: Figueroa-López, José E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: The estimation of the Lévy density, the infinite-dimensional parameter controlling the jump dynamics of a Lévy process, is considered here under a discrete-sampling scheme. In this setting, the jumps are latent variables, the statistical properties of which can be assessed when the frequency and time horizon of observations increase to infinity at suitable rates. Nonparametric estimators for the Lévy density based on Grenander's method of sieves was proposed in Figueroa-López [IMS Lecture Notes 57 (2009) 117--146]. In this paper, central limit theorems for these sieve estimators, both pointwise and uniform on an interval away from the origin, are obtained, leading to pointwise confidence intervals and bands for the Lévy density. In the pointwise case, our estimators converge to the Lévy density at a rate that is arbitrarily close to the rate of the minimax risk of estimation on smooth Lévy densities. In the case of uniform bands and discrete regular sampling, our results are consistent with the case of density estimation, achieving a rate of order arbitrarily close to $\log^{-1/2}(n)\cdot n^{-1/3}$, where $n$ is the number of observations. The convergence rates are valid, provided that $s$ is smooth enough and that the time horizon $T_n$ and the dimension of the sieve are appropriately chosen in terms of $n$.
description: Published in at http://dx.doi.org/10.3150/10-BEJ286 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm)
Extremal and nonextremal Kerr/CFT correspondences
Creators: name: Carlip, S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: I rederive the Kerr/CFT correspondence without first taking the near-horizon extremal Kerr limit. This method extends easily to nonextremal black holes, for which the temperature and central charge behave poorly at the horizon but the entropy remains finite. A computation yields one-half of the standard Bekenstein-Hawking entropy, with hints that the other half may be related to a conformal field theory at the inner horizon. I then present an alternative approach, based on a stretched Killing horizon, in which the full entropy is obtained and the temperature and central charge remain well-behaved even in the nonextremal case.
description: v3: missing term restored in eqn. (A.10) for central term; does not affect conclusions of this paper, but important in other contexts
The Energy Spectrum of Anomalous X-ray Pulsars and Soft Gamma-ray Repeaters
Creators: name: Trümper, J.
name: Zezas, A.
name: Ertan, Ü.
name: Kylafis, N. D.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Assuming that AXPs and SGRs accrete matter from a fallback disk, we attempt to explain both the soft and the hard X-ray emission as the result of the accretion process. We also attempt to explain their radio emission or the lack of it. We test the hypothesis that the power-law, hard X-ray spectra are produced in the accretion flow mainly by bulk-motion Comptonization of soft photons emitted at the neutron star surface. Fallback disk models invoke surface dipole magnetic fields of $10^{12} - 10^{13}$ G, which is what we assume here. Unlike normal X-ray pulsars, for which the accretion rate is highly super-Eddington, the accretion rate is approximately Eddington in AXPs and SGRs and thus the bulk-motion Comptonization operates efficiently. As an illustrative example we reproduce both the hard and the soft X-ray spectra of AXP 4U 0142+61 well using the XSPEC package compTB. Our model seems to explain both the hard and the soft X-ray spectra of AXPs and SGRs, as well as their radio emission or the lack of it, in a natural way. It might also explain the short bursts observed in these sources. On the other hand, it cannot explain the giant X-ray outbursts observed in SGRs, which may result from the conversion of magnetic energy in local multipole fields.
description: 6 pages, 2 figures, minor corrections, accepted for publication in A&A
Рецензия на книгу «The Oxford History of Anglicanism» (Oxford, 2017)
Creators: name: Паламарчук Анастасия Андреевна
Publisher: name: Религия. Церковь. Общество
Year: 2018
Subjects: АНГЛИКАНСТВО
ЦЕРКОВЬ АНГЛИИ
ПРОТЕСТАНТИЗМ
РЕФОРМАЦИЯ
ТЮДОРЫ
СТЮАРТЫ
ANGLICANISM
CHURCH OF ENGLAND
PROTESTANTISM
REFORMATION
THE TUDORS
THE STUARTS

description: Рецензия освещает основные дискуссионные направления и содержательные новации издания «Оксфордская история англиканства. Том 1. Реформация и идентичность, 1520-1662» под редакцией А. Мильтона. Предложенная авторским коллективом концепция англиканства как «оспариваемой идентичности» и рассмотрение англиканства как глобального культурно-исторического явления представляют собой новый яркий этап в изучении истории Церкви Англии.The reviewed volume «The Oxford History of Anglicanism. Vol. 1. Reformation and Identity, с. 1520-1662 » (Ed. by A. Milton. Oxford, 2017) definitely is a seminal work on English ecclesiastical history. The concept of the Church of England as a «contested identity» and Anglicanism as a global cultural-historical phenomenon open a new perspective for the historians of the Church of England.
Understanding ‘it depends’ in ecology : a guide to hypothesising, visualising and interpreting statistical interactions
Creators: name: Spake, Rebecca
name: Bowler, Diana E.
name: Callaghan, Corey T.
name: Blowes, Shane A.
name: Doncaster, C. Patrick
name: Antao, Laura H.
name: Nakagawa, Schinichi
name: McElreath, Richard
name: Chase, Jonathan
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 577

description: Ecologists routinely use statistical models to detect and explain interactions among ecological drivers, with a goal to evaluate whether an effect of interest changes in sign or magnitude in different contexts. Two fundamental properties of interactions are often overlooked during the process of hypothesising, visualising and interpreting interactions between drivers: the measurement scale – whether a response is analysed on an additive or multiplicative scale, such as a ratio or logarithmic scale; and the symmetry – whether dependencies are considered in both directions. Overlooking these properties can lead to one or more of three inferential errors: misinterpretation of (i) the detection and magnitude (Type-D error), and (ii) the sign of effect modification (Type-S error); and (iii) misidentification of the underlying processes (Type-A error). We illustrate each of these errors with a broad range of ecological questions applied to empirical and simulated data sets. We demonstrate how meta-analysis, a widely used approach that seeks explicitly to characterise context dependence, is especially prone to all three errors. Based on these insights, we propose guidelines to improve hypothesis generation, testing, visualisation and interpretation of interactions in ecology.
Рецензия на сборник «о Вавилонском пленении Церкви» под ред. И. Фокина (СПб. , 2017)
Creators: name: Савинов Родион Валентинович
Publisher: name: Религия. Церковь. Общество
Year: 2018
Subjects: ЛЮТЕР
РЕФОРМАЦИЯ
ПРОТЕСТАНТИЗМ
ЛЮТЕРАНСТВО
ЮБИЛЕЙ РЕФОРМАЦИИ
РЕЦЕНЗИЯ
LUTHER
REFORMATION
PROTESTANTISM
LUTHERANISM
ANNIVERSARY OF THE REFORMATION
REVIEW

description: Автор рассматривает собрание работ М. Лютера под редакцией И. Фокина, приуроченное к 500-летию начала Реформации. Дается описание содержания сборника, анализ ключевых текстов из каждого раздела. Предлагается оценка данного издания в контексте российской исследовательской литературы, посвященной Реформации и раннему Новому времени.The author considers the collection of Martin Luther’s works, edited by Ivan Fokin, timed to the 500th anniversary of the Reformation. The review included description of the collection, and analysis of key texts from each section. An evaluation of this edition is suggested in the context of Russian research literature devoted to the Reformation and the early Modern.
The 2013 KIT IWSLT Speech-to-Text Systems for German and English
Creators: name: Kilgour, Kevin
name: Mohr, Christian
name: Heck, Michael
name: Nguyen, Quoc Bao
name: Nguyen, Van Huy
name: Shin, Evgeniy
name: Tseyzer, Igor
name: Gehring, Jonas
name: Müller, Markus
name: Sperber, Matthias
name: Stüker, Sebastian
name: Waibel, Alex
Publisher: name: Association for Computational Linguistics (ACL)
Year: 2013

description: This paper describes our English Speech-to-Text (STT) systems for the 2013 IWSLT TED ASR track. The systems consist of multiple subsystems that are combinations of different front-ends, e.g. MVDR-MFCC based and lMel based ones, GMM and NN acoustic models and different phone sets. The outputs of the subsystems are combined via confusion network combination. Decoding is done in two stages, where the systems of the second stage are adapted in an unsupervised manner on the combination of the first stage outputs using VTLN, MLLR, and cMLLR.
Clebsch Potentials in the Variational Principle for a Perfect Fluid
Creators: name: Fukagawa, Hiroki
name: Fujitani, Youhei
Publisher: name: arXiv
Year: 2010
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Equations for a perfect fluid can be obtained by means of the variational principle both in the Lagrangian description and in the Eulerian one. It is known that we need additional fields somehow to describe a rotational isentropic flow in the latter description. We give a simple explanation for these fields; they are introduced to fix both ends of a pathline in the variational calculus. This restriction is imposed in the former description, and should be imposed in the latter description. It is also shown that we can derive a canonical Hamiltonian formulation for a perfect fluid by regarding the velocity field as the input in the framework of control theory.
description: 15 pages
No evidence for mate copying in Danio rerio
Creators: name: Nöbel, Sabine
name: Wang, Xiaobo
name: Cristante, Marion
name: Guell, Marine
name: Tariel, Juliette
name: Danchin, Etienne
name: Roussigné, Myriam
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 597

description: The zebrafish Danio rerio is an important model organism, but little is known about its mating preferences and how these are influenced by personality traits like boldness. In this study, we tested two strains of zebrafish and addressed whether females used social information to build a mating preference, a behavior called mate copying, and whether this social learning was affected by boldness. Thus, we provided positive social information for small males to test whether female zebrafish changed their mate preference after observing a pair of a small and a large male with a demonstrator female next to the small one. After that, we tested the observer female in a test maze to evaluate boldness. We found no significant evidence for mate copying as females did not change their preference for the small male after witnessing the large male alone and the small male interacting with another female and chose consistently larger males in a control without opportunity to copy. Whether the female was defined as shy or bold had no effect on mate copying. We conclude that mate copying is probably inexistent or only relatively weak in this species.
Study of friction of Ag and Ni nanoparticles: an atomistic approach
Creators: name: Khomenko, Alexei V.
name: Prodanov, Nikolay V.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Manipulation of metal nanoparticles using atomic force microscope is a promising new technique for probing tribological properties at the nanoscale. In spite of some advancements in experimental investigations, there is no unambiguous theoretical treatment of processes accompanying the movement of metallic nanoislands adsorbed on a flat surface and additional research is required. In this paper, we describe computer experiments based on classical molecular dynamics in which the behavior of silver and nickel nanoparticles interacting with a graphene sheet and sheared with constant force is studied. Frictional force acting on the nanoislands is measured as a function of their size. It is shown that its average value grows approximately linearly with contact area, and slopes of linear fits are close to the experimentally observable ones. The dependence of the friction force value and of the shape of the measured friction curves on the type of metal atom is revealed and its possible reasons originating from atomistic background are discussed.
description: 23 pages, 9 figures
A rolling horizon approach for shunting operations : an emission oriented simulation study
Creators: name: Zien, Max
name: Kirschstein, Thomas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 330

description: Marshalling yards are nodes in rail networks to sort railcars from incoming trains to outgoing trains. To built outgoing trains in the correct sequence, railcars are shunted by shunting locomotives. Thereby, green house gas emissions are emitted as those locomotives are usually diesel powered. As the planning of shunting operations is a very complex problem, heuristics, so-called sorting strategies, are applied in practice. In this paper the effects of practically relevant sorting strategies on green house gas emissions are studied in a rolling horizon model. The rolling horizon model is used in a simulation study to investigate the effects of sorting strategies and input parameters (like the number and composition of ingoing and outgoing trains) on green house gas emissions. The results indicate that for different parameter constellations, different emission-optimal sorting strategies exist. Thus, sorting strategy selection should be done carefully depending on the operational conditions at the shunting yards.
Piano exams : understanding why we do them
Creators: name: Ma, Amy
Publisher: name: University of British Columbia
Year: 2021

description: Some students commit to many years of study in classical piano and achieve high levels of certification but do not show much interest in playing the instrument afterwards. The purpose of this study was to explore social and cultural norms that impact long-term student motivations to attain high-level piano qualifications in cases where students have no subsequent plans to pursue professional musical activities. Semi-structured interviews were conducted with 9 ex-piano students, all of whom were enrolled in or had recently completed graduate programs in fields other than music or music education. Bourdieu’s theories of cultural capital and habitus provided the framework for data analysis. Self-Determination Theory was then applied to the narratives to determine if each student had internalized the belief that the piano credential was a valuable asset. The narratives showed a theme of concerted cultivation by parents. All participants exhibited a habitus of scholarly study that extended to their classical piano studies. Students became self-motivated when they reached a minimal skill threshold by the age of approximately 11 years, and confidence in their own competence fueled the desire to continue with their piano studies. Students felt that ownership of a piano qualification validated their ability to play, although none expressed the belief that these qualifications brought social or economic benefits. Further research to include a more diverse group, including parents, teachers, and non-graduate students, would provide more insight into whether these patterns can be applied more generally to classical piano study and to other extracurricular activities.
The governance of sustainable business model innovation : an ordonomic approach
Creators: name: Pies, Ingo
name: Schultz, Felix Carl
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 330

description: This paper develops an ordonomic approach to the governance of sustainable business model innovation (SBMI). We clarify the distinctive roles of optimization and governance for the management of sustainable value networks and develop a sustainability cube as a new management tool for the governance of SBMI. Our cube helps management to identify and overcome social dilemmas within value networks, i.e. to form and reform relevant business relationships, thus creating and tapping second-order win-win-win potentials. Furthermore, our cube encourages management to interpret negative externality problems as “missing markets”, i.e. as an entrepreneurial challenge and as a business opportunity to serve as yet unmet needs. Finally, our cube offers an avenue to develop and strengthen the specific management competencies that foster a successful governance of SBMI.
Flexible control of the Peierls transition in metallic C$_{60}$ polymers
Creators: name: Ono, Shota
name: Shima, Hiroyuki
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The metal-semiconductor transition of peanut-shaped fullerene (C$_{60}$) polymers is clarified by considering the electron-phonon coupling in the uneven structure of the polymers. We established a theory that accounts for the transition temperature $T_c$ reported in a recent experiment and also suggests that $T_c$ is considerably lowered by electron doping or prolonged irradiation during synthesis. The decrease in $T_c$ is an appealing phenomenon with regard to realizing high-conductivity C$_{60}$-based nanowires even at low temperatures.
description: 3 pages, 3 figures
Cardiac roles of Serotonin (5-HT) and 5-HT-receptors in health and disease
Creators: name: Neumann, Joachim
name: Hofmann, Britt
name: Dhein, Stefan
name: Gergs, Ulrich
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Serotonin acts solely via 5-HT4-receptors to control human cardiac contractile function. The effects of serotonin via 5-HT4-receptors lead to positive inotropic and chronotropic effects, as well as arrhythmias, in the human heart. In addition, 5-HT4-receptors may play a role in sepsis, ischaemia, and reperfusion. These presumptive effects of 5-HT4-receptors are the focus of the present review. We also discuss the formation and inactivation of serotonin in the body, namely, in the heart. We identify cardiovascular diseases where serotonin might play a causative or additional role. We address the mechanisms which 5-HT4-receptors can use for cardiac signal transduction and their possible roles in cardiac diseases. We define areas where further research in this regard should be directed in the future, and identify animal models that might be generated to this end. Finally, we discuss in what regard 5-HT4-receptor agonists or antagonists might be useful drugs that could enter clinical practice. Serotonin has been the target of many studies for decades; thus, we found it timely to summarise our current knowledge here.
ЭТИЛИШИГА ИМКОН БЕРГАН ШАРТ-ШАРОИТЛАРНИ АНИҚЛАШ ВА БАРТАРАФ ЭТИШ ФАОЛИЯТИНИ  ТАКОМИЛЛАШТИРИШ
Creators: name: Мустофақулов, Бобур
name: Дўсмуродов, Мирдамир
Publisher: name: Zenodo
Year: 2025

description: Ушбу мақолада профилактика (катта) инспекторларининг  ҳуқуқбузарликларнинг сабаблари ва содир этилишига имкон берган             шарт-шароитларни аниқлаш ва бартараф этиш фаолияти бўйича, ҳуқуқбузарликларнинг сабаблари ва уларга имкон бераётган                              шарт-шароитларни аниклаш хамда олдини олиш, тақдимнома ва унинг турлари, профилактика инспекторлари томонидан ҳуқуқбузарликларнинг сабаблари ва содир этилишига имкон берган шарт-шароитларни аниқлаш ва уларни бартараф этиш бўйича киритилган тақдимномаларни бажармаслик бўйича жавобгарлик масалалари  ҳақида сўз боради.
In cellulo and in vivo assays for compound testing against Trypanosoma cruzi
Creators: name: Pavao Guerra-Slompo, Eloise
name: Picchi-Constante, Gisele Fernanda Assine
name: Marek, Martin
name: Romier, Christophe
name: Sippl, Wolfgang
name: Zanchin, Nilson Ivo Tonin
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 615

description: Here, we describe a combined in cellulo and in vivo approach to identify compounds with higher potential for efficient inhibition of Trypanosoma cruzi. Phase I of in cellulo assays is designed to exclude inactive or toxic compounds, while phase II is designed for accurate IC50, CC50, and selective index (SI) determination. Compounds showing high SI are tested using in vivo infection models in parallel with benznidazole to assess their efficacy relative to a reference drug used for Chagas disease treatment.
Topological insulators and metal-insulator transition in the pyrochlore iridates
Creators: name: Yang, Bohm-Jung
name: Kim, Yong Baek
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The possible existence of topological insulators in cubic pyrochlore iridates A$_{2}$Ir$_{2}$O$_{7}$ (A = Y or rare-earth elements) is investigated by taking into account the strong spin-orbit coupling and trigonal crystal field effect. It is found that the trigonal crystal field effect, which is always present in real systems, may destabilize the topological insulator proposed for the ideal cubic crystal field, leading to a metallic ground state. Thus the trigonal crystal field is an important control parameter for the metal-insulator changeover. We propose that this could be one of the reasons why distinct low temperature ground states may arise for the pyrochlore iridates with different A-site ions. On the other hand, examining the electron-lattice coupling, we find that softening of the $\textbf{q}$=0 modes corresponding to trigonal or tetragonal distortions of the Ir pyrochlore lattice leads to the resurrection of the strong topological insulator. Thus, in principle, a finite temperature transition to a low-temperature topological insulator can occur via structural changes. We also suggest that the application of the external pressure along [111] or its equivalent directions would be the most efficient way of generating strong topological insulators in pyrochlore iridates.
description: 10 pages, 11 figures, 2 tables
Ergotamine stimulates human 5-HT4-serotonin receptors and human H2-histamine receptors in the heart
Creators: name: Jacob, Hannes
name: Braekow, Pauline
name: Schwarz, Rebecca Lia
name: Höhm, Christian
name: Kirchhefer, Uwe
name: Hofmann, Britt
name: Neumann, Joachim
name: Gergs, Ulrich
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Ergotamine (2′-methyl-5′α-benzyl-12′-hydroxy-3′,6′,18-trioxoergotaman) is a tryptamine-related alkaloid from the fungus Claviceps purpurea. Ergotamine is used to treat migraine. Ergotamine can bind to and activate several types of 5-HT1-serotonin receptors. Based on the structural formula of ergotamine, we hypothesized that ergotamine might stimulate 5-HT4-serotonin receptors or H2-histamine receptors in the human heart. We observed that ergotamine exerted concentration- and time-dependent positive inotropic effects in isolated left atrial preparations in H2-TG (mouse which exhibits cardiac-specific overexpression of the human H2-histamine receptor). Similarly, ergotamine increased force of contraction in left atrial preparations from 5-HT4-TG (mouse which exhibits cardiac-specific overexpression of the human 5-HT4-serotonin receptor). An amount of 10 µM ergotamine increased the left ventricular force of contraction in isolated retrogradely perfused spontaneously beating heart preparations of both 5-HT4-TG and H2-TG. In the presence of the phosphodiesterase inhibitor cilostamide (1 µM), ergotamine 10 µM exerted positive inotropic effects in isolated electrically stimulated human right atrial preparations, obtained during cardiac surgery, that were attenuated by 10 µM of the H2-histamine receptor antagonist cimetidine, but not by 10 µM of the 5-HT4-serotonin receptor antagonist tropisetron. These data suggest that ergotamine is in principle an agonist at human 5-HT4-serotonin receptors as well at human H2-histamine receptors. Ergotamine acts as an agonist on H2-histamine receptors in the human atrium.
Effect of parental exposure to o,p̕ -DDT on the behavior of Atlantic croaker, Micropogonias undulatus, larvae
Creators: name: Faulk, Cynthia Kathleen
Publisher: name: The University of Texas at Austin
Year: 1997
Subjects: subject: Atlantic croaker
subject: Atlantic croaker larvae
subject: Effect of DDT on larvae
subject: Effect of DDT on Atlantic croaker
subject: Atlantic croaker larvae behavior
subject: DDT physiological effect
subject: Larvae behavior
subject: Effect of DDT on fish larvae
subject: Micropogonias undulatus
subject: Atlantic croaker--Larvae--Effect of insecticides on
subject: Atlantic croaker--Larvae--Behavior
subject: DDT (Insecticide)--Physiological effect

description: Three behavioral assays were evaluated as indicators of sublethal toxicity due to parental exposure to o,p'-DDT in Atlantic croaker, Micropogonias undulatus, larvae. Responses to separate visual and vibratory stimuli as well as routine swimming activity were quantified using image and motion analysis equipment. Of the variables examined, proportion of larvae responding to a vibratory stimulus, swimming speed, active duration, and pause duration were the most sensitive indicators of exposure to o,p'-DDT. Average and maximum burst speeds in response to the visual stimulus were higher for control larvae. However, these same measurements were not different among treatments in response to the vibratory stimulus. The proportion of larvae responding to the vibratory stimulus was significantly higher for unexposed (control) larvae only after yolk and oil absorption. Effects of DDT exposure on routine swimming activity were only observed prior to complete oil absorption. During this time, apparent swimming speeds were reduced for exposed larvae due to decreases in the duration of active swimming and increases in the duration of intervening pauses. The implications of these behavioral changes for the survival of parentally exposed larvae are discussed
General relativistic polarized radiative transfer: building a dynamics-observations interface
Creators: name: Shcherbakov, Roman V.
name: Huang, Lei
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The rising amount of polarized observations of relativistic sources requires the correct theory for proper model fitting. The equations for general relativistic (GR) polarized radiative transfer are derived starting from the Boltzmann equation and basic ideas of general relativity. The derivation is aimed at providing a practical guide to reproducing the synchrotron part of radio & sub-mm emission from low luminosity active galactic nuclei (LLAGNs), in particular Sgr A*, and jets. The recipe for fast exact calculation of cyclo-synchrotron emissivities, absorptivities, Faraday rotation and conversion coefficients is given for isotropic particle distributions. The multitude of physical effects influencing simulated spectrum is discussed. The application of the prescribed technique is necessary to determine the black hole (BH) spin in LLAGNs, constraining it with all observations of total flux, linear and circular polarization fractions, and electric vector position angle as functions of the observed frequency.
description: 9 pages, 3 figures, accepted by MNRAS
title: Ð Ð¾ÑÑ ÑÐ¿Ð¸ÑÐ°ÐºÑÐ¸Ð°Ð»ÑÐ½ÑÑ ÑÐ»Ð¾ÐµÐ² Ð¸ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² Ð¾ÐºÑÐ¸Ð´Ð° Ð³Ð°Ð»Ð»Ð¸Ñ ÑÑÐ±Ð»Ð¸Ð¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¼ Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Growth of epitaxial layers and crystals by physical vapor transport
Creators: name: Ð¢Ð°ÑÐ²Ð°Ð½ÐµÐ½, ÐÐ¼Ð¸ÑÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÑÑÐ±Ð»Ð¸Ð¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¹ Ð¼ÐµÑÐ¾Ð´
Ð¼ÐµÑÐ¾Ð´ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ°
ÑÐ¿Ð¸ÑÐ°ÐºÑÐ¸Ð°Ð»ÑÐ½ÑÐµ ÑÐ»Ð¾Ð¸
ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ñ
Ð¾ÐºÑÐ¸Ð´ Ð³Ð°Ð»Ð»Ð¸Ñ
sublimation
physical vapor transport
epitaxial layer
crystals
gallium oxide

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸ ÑÐ¾ÑÑÐ° ÑÐ¿Ð¸ÑÐ°ÐºÑÐ¸Ð°Ð»ÑÐ½ÑÑ ÑÐ»Ð¾ÐµÐ² Ð¸ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² Ð¾ÐºÑÐ¸Ð´Ð° Ð³Ð°Ð»Ð»Ð¸Ñ ÑÑÐ±Ð»Ð¸Ð¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¼ Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼. ÐÐ·ÑÑÐµÐ½Ñ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÑÐµÑÑÐ° ÑÑÐ±Ð»Ð¸Ð¼Ð°ÑÐ¸Ð¸ Ð´Ð»Ñ ÑÐ¾ÑÑÐ° ÑÑÐ¾Ð¶Ð¸Ñ Ð¿Ð¾ ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ð¼ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð°Ð¼ Ñ Ð¾ÐºÑÐ¸-Ð´Ð¾Ð¼ Ð³Ð°Ð»Ð»Ð¸Ñ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð¾Ð². ÐÑÐ»Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ñ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÑ Ð¿Ð¾ ÑÐ¾ÑÑÑ ÑÐ¿Ð¸ÑÐ°ÐºÑÐ¸Ð°Ð»ÑÐ½ÑÑ ÑÐ»Ð¾ÐµÐ² Ð¸ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ð¾Ð² Ð¾ÐºÑÐ¸Ð´Ð° Ð³Ð°Ð»Ð»Ð¸Ñ Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼ ÑÑÐ±Ð»Ð¸Ð¼Ð°ÑÐ¸Ð¸. ÐÐ¾ÑÐ»Ðµ Ð±ÑÐ»Ð¸ Ð¸Ð·ÑÑÐµÐ½Ñ ÑÑÑÑÐºÑÑÑÐ° Ð¸ ÑÐ¾ÑÑÐ°Ð² Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ð¾Ð±ÑÐ°Ð·ÑÐ¾Ð². Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð±ÑÐ»Ð¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ñ ÑÐ¿Ð¸ÑÐ°ÐºÑÐ¸Ð°Ð»ÑÐ½ÑÐµ ÑÐ»Ð¾Ð¸ Ð¸ ÐºÑÐ¸ÑÑÐ°Ð»Ð»Ñ Ð½Ð° Ð¿Ð¾Ð´Ð»Ð¾Ð¶ÐºÐ°Ñ Ð¸Ð· ÑÐ°Ð¿ÑÐ¸ÑÐ° Ð¸ ÐºÐ°ÑÐ±Ð¸Ð´Ð° ÐºÑÐµÐ¼Ð½Ð¸Ñ.
description: In this work, the possibilities of growing epitaxyl layers and crystals of gallium oxide using physical vapor transport are considered. The features of the sublimation process for the growth of materials similar in physical properties to gallium oxide have been studied. Experiments were carried out on the growth of epitaxial layers and gallium oxide crystals by the sublimation method. After that, the structure and composition of the obtained samples were studied. As a result, epitaxial layers and crystals on sapphire and silicon carbide substrates were ob-tained.
Bounded confidence model: addressed information maintain diversity of opinions
Creators: name: Malarz, Krzysztof
name: Kulakowski, Krzysztof
Publisher: name: arXiv
Year: 2011
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: A community of agents is subject to a stream of messages, which are represented as points on a plane of issues. Messages are sent by media and by agents themselves. Messages from media shape the public opinion. They are unbiased, i.e. positive and negative opinions on a given issue appear with equal frequencies. In our previous work, the only criterion to receive a message by an agent is if the distance between this message and the ones received earlier does not exceed the given value of the tolerance parameter. Here we introduce a possibility to address a message to a given neighbour. We show that this option reduces the unanimity effect, what improves the collective performance.
description: 3 pages, 4 figures, RevTeX 4.1, presented at the 5th Polish Symposium on Econo- and Sociophysics, Nov. 25-27, 2010, Warsaw (PL)
Neutrino physics
Creators: name: Hernandez, P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The topics discussed in this lecture include: general properties of neutrinos in the SM, the theory of neutrino masses and mixings (Dirac and Majorana), neutrino oscillations both in vacuum and in matter, an overview of the experimental evidence for neutrino masses and of the prospects in neutrino oscillation physics. We also briefly review the relevance of neutrinos in leptogenesis and in beyond-the-Standard-Model physics.
description: 49 pages, 47 figures, Lectures given at the 5th CERN-Latin-American School of High-Energy Physics, Recinto Quirama, Colombia, 15 - 28 Mar 2009
Additional file 1: of Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression
Creators: name: Wang, Liyan
name: Long, Haiyan
name: Zheng, Qinghua
name: Bo, Xiaotong
name: Xiao, Xuhua
name: Li, Bin
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology

description: Additional informations. (DOCX 1045 kb)
title: Ð Ð¾Ð»Ñ Ð¼ÐµÑÐ¸Ð»ÑÑÐ°Ð½ÑÑÐµÑÐ°Ð·Ñ Set7/9 Ð² ÑÐµÐ³ÑÐ»ÑÑÐ¸Ð¸ Ð°ÑÑÐ¾ÑÐ°Ð³Ð¸Ð¸ Ð² ÑÐ°ÐºÐ¾Ð²ÑÑ ÐºÐ»ÐµÑÐºÐ°Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: The role of Set7/9 methyltransferase in the regulation of autophagy in cancer cells
Creators: name: ÐÐ²Ð°Ð½Ð¾Ð², ÐÐ°ÑÐ²ÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐÐ»ÐµÑÐºÐ° (Ð±Ð¸Ð¾Ð».)
Ð°ÑÑÐ¾ÑÐ°Ð³Ð¸Ñ
Ð¼ÐµÑÐ¸Ð»ÑÑÐ°Ð½ÑÑÐµÑÐ°Ð·Ð° Set7/9
Ð°Ð´ÐµÐ½Ð¾ÐºÐ°ÑÑÐ¸Ð½Ð¾Ð¼Ð° Ð»ÐµÐ³ÐºÐ¾Ð³Ð¾

description: Ð Ð½Ð°ÑÑÐ¾ÑÑÐµÐ¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¾Ð±Ð¾Ð±ÑÐ°ÑÑÑÑ Ð´Ð°Ð½Ð½ÑÐµ Ð¾Ð± ÑÑÐ°ÑÑÐ¸Ð¸ Ð¼ÐµÑÐ¸Ð»ÑÑÐ°Ð½ÑÑÐµÑÐ°Ð·Ñ Set7/9 Ð² ÑÐµÐ³ÑÐ»ÑÑÐ¸Ð¸ Ð°ÑÑÐ¾ÑÐ°Ð³Ð¸Ð¸; Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð²Ð»Ð¸ÑÐ½Ð¸Ñ Ð½Ð¾ÐºÐ´Ð°ÑÐ½Ð° Set7/9 Ð½Ð° ÑÑÐ¾Ð²ÐµÐ½Ñ Ð°ÑÑÐ¾ÑÐ°Ð³Ð¸Ð¸ Ð² ÐºÐ»ÐµÑÐºÐ°Ñ Ð°Ð´ÐµÐ½Ð¾ÐºÐ°ÑÑÐ¸Ð½Ð¾Ð¼Ñ Ð»ÑÐ³ÐºÐ¾Ð³Ð¾ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ° H1299 ÐºÐ°Ðº Ð² Ð½Ð¾ÑÐ¼Ð°Ð»ÑÐ½ÑÑ ÑÑÐ»Ð¾Ð²Ð¸ÑÑ, ÑÐ°Ðº Ð¸ Ð¿Ð¾Ð´ Ð²Ð¾Ð·Ð´ÐµÐ¹ÑÑÐ²Ð¸ÐµÐ¼ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ ÑÐ¸Ð¿Ð¾Ð² ÑÑÑÐµÑÑÐ°. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð±ÑÐ»Ð¾ Ð¿Ð¾ÐºÐ°Ð·Ð°Ð½Ð¾, ÑÑÐ¾ Set7/9 Ð²Ð»Ð¸ÑÐµÑ Ð½Ð° Ð¸Ð½Ð´ÑÐºÑÐ¸Ñ Ð°ÑÑÐ¾ÑÐ°Ð³Ð¸Ð¸ Ð¿ÑÐ¸ Ð³ÐµÐ½Ð¾ÑÐ¾ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¼ ÑÑÑÐµÑÑÐµ, Ð° ÑÐ°ÐºÐ¶Ðµ, ÑÑÐ¾ ÐºÐ»ÐµÑÐºÐ¸ Ñ Ð½Ð¾ÐºÐ´Ð°ÑÐ½Ð¾Ð¼ Set7/9 Ð±Ð¾Ð»ÐµÐµ ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ñ Ðº Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ°Ð¼ Ð´ÐµÐ¹ÑÑÐ²Ð¸Ðµ ÐºÐ¾ÑÐ¾ÑÑÑ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¾ Ð½Ð° Ð¿Ð¾Ð²ÑÐµÐ¶Ð´ÐµÐ½Ð¸Ðµ ÐÐÐ.
description: The thesis summarizes on the involvement of Set7/9 methyltransferase in the regulation of autophagy; a study of the effect of Set7/9 knockdown on the level of autophagy in human lung adenocarcinoma cells H1299 both under normal conditions and under various types of stress. As a result of the study, it was shown that Set7 / 9 affects the induction of autophagy under genotoxic stress, and that cells with a Set7/9 knockdown are more sensitive to drugs whose action is aimed at DNA damage.
Reflections on a Feminist Now in Places of Undying Colonialism
Creators: name: Talve-Goodman, Sarika
Publisher: name: Zenodo
Year: 2017
Subjects: Apartheid
South Africa
Fenimism
Colonializm

description: Reflections on a conference in collaboration between our ERC
 project, APARTHEID-STOPS, The World Literatures: Cosmopolitan
 and Vernacular Dynamics Research Programme at Stockholm
 University and the Wits Institute for Social and Economic Research
 (WiSER) in Johannesburg presented the opportunity for
 participants to enter into dialogue concerning our different
 localized and ongoing political struggles.
Density profile of interacting Fermions in a one-dimensional optical trap
Creators: name: Soeffing, Stefan A.
name: Eggert, Sebastian
name: Bortz, Michael
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The density distribution of the one-dimensional Hubbard model in a harmonic trapping potential is investigated in order to study the effect of the confining trap. Strong superimposed oscillations are always present on top of a uniform density cloud, which show universal scaling behavior as a function of increasing interactions. An analytical formula is proposed on the basis of bosonization, which describes the density oscillations for all interaction strengths. The wavelength of the dominant oscillation changes with interaction, which indicates the crossover to a spin-incoherent regime. Using the Bethe ansatz the shape of the uniform fermion cloud is analyzed in detail, which can be described by a universal scaling form.
description: 5 pages, 4 figures. Published version. See also http://www.physik.uni-kl.de/eggert/papers/index.html
Evaluating the association between dietary patterns and cardiovascular disease risk in Canadian adults : evidence from the Canadian Community Health Survey-Nutrition
Creators: name: Lazarova, Svilena
Publisher: name: University of British Columbia
Year: 2024

description: The study of dietary patterns has become crucial for the formulation of nutritional guidelines and policy applications for reducing the burden of chronic disease. Using the Canadian Community Health Survey (CCHS)-Nutrition (2004 and 2015) linked to health administrative databases, the main objectives of this thesis were to investigate the characteristics of Canadian adults’ dietary patterns and to explore their associations with cardiovascular disease (CVD) risk at the national population level. In Study 1, adherence to three emerging plant-based dietary patterns was examined (using a priori dietary quality indices) and was shown to be low. Closer compliance to these dietary patterns was associated with healthier lifestyle behaviours, higher intake of healthy foods and nutrients, and lower risk of obesity, even though it was not related to CVD risk (incidence and mortality). In Study 2, data reduction techniques (hybrid methods) were compared in derivation of dietary patterns associated with high CVD risk (energy-dense, high-saturated-fat and low-fibre-density). Results revealed highly similar trends and highlighted key food components that could be targeted for CVD prevention among Canadian adults. Overall, findings in this thesis present comprehensive evidence on adherence to different dietary patterns in Canada with the potential for chronic disease risk reduction, and set the scene for formulation of future comprehensive studies on alternative dietary patterns among different population subgroups to further inform nutrition policies and clinical practical guidelines for CVD prevention.