cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of Secondary use of health care data and left-over biosamples within the ‘Medical Informatics Initiative’ (MII): a quasi-randomized controlled evaluation of patient perceptions and preferences regarding the consent process
Creators: name: Roschka, Sybille
name: Leddig, Torsten
name: Bullerjahn, Mandy
name: Richter, Gesine
name: Liedtke, Wenke
name: Langanke, Martin
name: Hoffmann, Wolfgang
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. Questionnaire 2 (Process b: Interview-based questionnaire for participants choosing additional time for consideration before hypothetically deciding for or against the scientific use of the individual routine data and/or left-over samples.).
Sonnenfleckenzeichnung Nr. 22594.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.08.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Hexane fraction from Brazilian Morus nigra leaves improved oral carbohydrate tolerance and inhibits α-amylase and α-glucosidase activities in diabetic mice
Creators: name: da Silva, Dionísio Henrique Amaral
name: de Moura Barbosa, Humberto
name: de Almeida Beltrão, Raphaelle Lima
name: de França Oliveira Silva, Clarissa
name: Moura, Celuane Alves
name: Castro, Rosane Nora
name: da Silva Almeida, Jackson Roberto Guedes
name: Gomes, Dayane Aparecida
name: Lira, Eduardo Carvalho
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Morus nigra, popularly known as mulberry, has been traditionally used as anti-diabetic herbal medication. This study focused on hexane fraction from Brazilian M. nigra leaves (Hex-Mn) effects on digestion and absorption of carbohydrate in diabetic mice. The high-performance liquid chromatography (HPLC) analysis was performed, and showed the presence of flavonoids isoquercetin and kaempferol-3-O-rhamnoside. Hex-Mn did not alter oral glucose tolerance test; however, it prevented hyperglycemia in oral sucrose and starch tolerance test in diabetic mice. Also, Hex-Mn was more efficient to inhibit the α-glucosidase, showing lower inhibitory effect on α-amylase activity in vitro. The results suggest that Hex-Mn may delay the carbohydrate digestion, but not glucose transport through brush border membrane of the intestine, which contribute with reduction in postprandial hyperglycemia in mice. Hex-Mn has antihyperglycemic effect by attenuating the carbohydrate digestion in diabetic mice, which could be explained, at least in part, by the presence of isoquercetin and kaempferol-3-O-rhamnoside.
Chromosome translocation : development and characterization of a novel genetic selection system in yeast
Creators: name: Tennyson, Rachel B.
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Chromosome translocations occur when DNA is transferred from one chromosome to another or is exchanged between chromosomes. The process is known to start with two nonhomologous, intact chromosomes and to end with two nonhomologous derivative chromosomes carrying DNA from the translocation partner. However, what happens in between is very poorly understood. There are a number of reasons for this. One is that chromosome translocations probably occur by a number of different mechanisms. Based on breakpoint sequences and epidemiological studies of diseases characterized by chromosome translocations, many hypotheses have been made as to how translocations actually arise. These include misrepair of double-strand breaks by homologous and nonhomologous recombinational repair pathways and errors of site-directed recombination pathways. The process of translocation is poorly understood also because there is no selection system in a model organism to detect the untargeted types of translocations present in human diseases. It has become apparent over the last 10 years that although various eukaryotes preferentially use different double-strand break repair systems, all eukaryotes are capable of repairing double-strand breaks in essentially the same ways. Therefore the development of a chromosome translocation selection system in a model organism would be of great benefit in investigating this process. This dissertation describes the development and characterization of a novel genetic selection system for chromosome translocations in the yeast, Saccharomyces cerevisiae. The system specifically selects translocations between a translocation YAC and any chromosome in the yeast genome. The translocation products are analyzed by pulsed-field gel electrophoresis, Southern blot hybridization, PCR, and breakpoint sequencing. Such analyses provide insights into how translocations are happening within yeast and provide directions to pursue in future assays. Production of a specific double-strand break in the YAC increases the translocation rate as would be expected if formation of a double-strand break is rate-limiting in translocation. The assay works in yeast strains that have been made deficient in homologous recombination by deletion of RAD52 and limitation of homology between the YAC and the yeast genome. Product analysis and rates also suggest differences between haploid and diploid strains. The current results suggest that it will be possible to use this assay in yeast to study chromosome translocation in ways relevant to the processes in mammalian systems.
Canthon (Glaphyrocanthon) acutiformis Balthasar 1939
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Canthon
Canthon acutiformis

description: Canthon (Glaphyrocanthon) acutiformis Balthasar, 1939
Canthon acutiformis Balthasar 1939e: 231 (French Guiana)
Distribution. French Guiana: Balthasar 1939e: 231; Blackwelder 1944: 198 (as C. acutiforme); Vulcano and Pereira 1964: 603. Brazil (NA): Gardner et al. 2008: table S1 (NA).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 64, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 22651.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.10.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Chemical constituents from Artemisia vulgaris and their antiausterity activities against the PANC-1 human pancreatic cancer cell line
Creators: name: Omar, Ashraf M.
name: Dibwe, Dya Fita
name: Tawila, Ahmed M.
name: Sun, Sijia
name: Kim, Min Jo
name: Awale, Suresh
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: The 70% ethanolic extract of Artemisia vulgaris showed preferential cytotoxicity against PANC-1 human pancreatic cancer cells under a nutrient-deprived condition with PC50 12.5 μg/mL. A phytochemical investigation of this extract yielded a new bicyclic [4:3:0] sesquiterpene named (+)-vulgaric acid (1), together with eight previously reported compounds. The structural elucidation of 1 was achieved by HRFABMS and NMR analysis. The absolute configuration of 1 was deduced by computational calculations of ECD data. All isolated compounds were tested for preferential cytotoxicity against PANC-1 cells, and apigenin (3) showed the strongest activity with PC50 30.7 μM.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.12.1967, erstellt von Dursun Koçer an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
title: Mapping data acquisition and processing report, cruise EX-14-02 Leg 3 : Exploration, Gulf of Mexico rov & mapping, April 10, - May 1, 2014 Galveston, Texas - Tampa, Florida
Creators: name: Lobecker, Elizabeth
name: Elliott, Kelley
name: Rose, Emily
name: James, Jackyln
name: Miller, Jeffrey
Publisher: name: Ocean Exploration Program
Year: 2017

description: Mapping objectives for the cruise included site characterization at ROV dive locations, and extending existing mapping data coverage in the region.The full set of cruise objectives for EX-14-02 Leg 3 were defined in EX-14-02 Leg 3 Project Instructions.
Sonnenfleckenzeichnung Nr. 22681.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.12.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Additional file 3 of Secondary use of health care data and left-over biosamples within the ‘Medical Informatics Initiative’ (MII): a quasi-randomized controlled evaluation of patient perceptions and preferences regarding the consent process
Creators: name: Roschka, Sybille
name: Leddig, Torsten
name: Bullerjahn, Mandy
name: Richter, Gesine
name: Liedtke, Wenke
name: Langanke, Martin
name: Hoffmann, Wolfgang
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3. Questionnaire 3 (Process b2: For participants choosing additional time for consideration and a written response by the participant.).
Sonnenfleckenzeichnung Nr. 22649.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.10.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.12.1967, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
New perspectives on the politics of Chinese environmental nongovernmental organizations: a case study of the Greener Beijing Institute
Creators: name: Shi, Xiao
Publisher: name: University of Utah
Year: 2012
Subjects: Environmentalism
Green movement
China
Non-governmental organizations

description: Environmental activism has emerged in China since the mid-1990s and environmental nongovernmental organizations (ENGOs) are becoming increasingly visible players in China‟s environmental politics, drawing hundreds of thousands of Chinese citizens into environmental activities. Through a close look at the Greener Beijing Institute (GBI), this thesis examines how this grassroots group has developed in a gradual way and the characteristics of it in the context of Chinese political and social conditions. The thesis also discusses the main campaigns GBI has carried out and what difficulties they have met with in the process to exemplify how the environmental movement actually operates in China. In conclusion, the thesis shows that Chinese ENGOs today tend to adopt a conciliatory style to raise public consciousness and expand the space for political participation. Nevertheless, the road ahead for China‟s ENGOs is still hard. They often lack necessary financial support, technical capacity and broad public participation.
Canthon (Glaphyrocanthon) acutus Harold 1868
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Canthon
Canthon acutus

description: Canthon (Glaphyrocanthon) acutus Harold, 1868
Canthon acutus Harold 1868a: 114 (Brazil, Colombia, U.S. Virgin Islands)
Distribution. Guyana: A. Schmidt 1922a: 72; Blackwelder 1944: 198 (as C. acutum). Brazil: Harold 1868a: 114; A. Schmidt 1922a: 72; Blackwelder 1944: 198 (as C. acutum). Venezuela: A. Schmidt 1922a: 72; Blackwelder 1944: 198 (as C. acutum); Martínez et al. 1964a: 10 (as Glaphyrocanthon acutus); Vulcano and Pereira 1964: 660 (as Glaphyrocanthon acutus). Other: Harold 1868a: 114 (Colombia, U.S. Virgin islands); Gillet 1911b: 27 (Colombia); A. Schmidt 1922a: 72 (Colombia, Trinidad and Tobago, U.S. Virgin Islands); Balthasar 1939e: 208 (Colombia); Blackwelder 1944: 198 (Colombia, Trinidad and Tobago, U.S. Virgin Islands - as C. acutum); Martínez et al. 1964a: 9, 10 (Colombia, Trinidad and Tobago - as Glaphyrocanthon acutus); Vulcano and Pereira 1964: 660 (Colombia - as Glaphyrocanthon acutus); Medina et al. 2001: 135 (Colombia).
Note. As far as we know, Canthon acutus has only been recorded for the research area by A. Schmidt (1922a: 72), who mentioned it for Guyana. The presence of this species in the research area needs to be confirmed.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 64, DOI: 10.5281/zenodo.3678492
Cytotoxicity and anti-inflammatory effects of the extract, fractions and alkaloids from Palicourea minutiflora (Rubiaceae)
Creators: name: de Moura, Vagner M.
name: Ames, Franciele Q.
name: Corrêa, José G. S.
name: Peixoto, Matheus A.
name: Amorim, André M. A.
name: Pomini, Armando M.
name: de Carvalho, João E.
name: Ruiz, Ana Lúcia T. G.
name: Bersani-Amado, Ciomar A.
name: Santin, Silvana M. O.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Palicourea species has been used in folk medicine in the treatment of some diseases including cancer and inflammatory disorders. This work aimed to evaluate the in vitro antiproliferative and in vivo topical anti-inflammatory activities of the methanolic extract, fractions and two major alkaloids isolated from Palicourea minutiflora. Methanolic extract, non-alkaloidal and alkaloidal fractions exhibited strong growth inhibition for ovarian cell lines (OVCAR-3, GI50 = 3.8 at 16.3 µg mL−1) and the vincosamide alkaloid revealed selective effect on the growth of glioma cell lines (U251, GI50 = 33.0 µg mL−1) compared with doxorubicin (DOX, GI50 = 0.42 and 0.025 µg mL−1, respectively) anticancer drug. Methanolic extract, fractions and strictosidinic acid showed significant inhibitory effect with 62.7% at 77.5% (p < 0.05) to ear edema induced by croton oil and 81% at 100% (p < 0.05) to myeloperoxidase assay compared with indomethacin (positive control) 68.4% and 91.3% (p < 0.05), respectively.
Additional file 4 of Secondary use of health care data and left-over biosamples within the ‘Medical Informatics Initiative’ (MII): a quasi-randomized controlled evaluation of patient perceptions and preferences regarding the consent process
Creators: name: Roschka, Sybille
name: Leddig, Torsten
name: Bullerjahn, Mandy
name: Richter, Gesine
name: Liedtke, Wenke
name: Langanke, Martin
name: Hoffmann, Wolfgang
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 4. Questionnaire 4 (Process b1: For participants choosing additional time for consideration and a visit of a study staff member at an appointed later point of time on the ward.)
Sonnenfleckenzeichnung Nr. 22652.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.10.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Shoot aqueous extract of Manihot esculenta Crantz (cassava) acts as a protective agent against paracetamol-induced liver injury
Creators: name: Elshamy, Abdelsamed I.
name: Gendy, Abd El-Nasser G. El
name: Farrag, Abdel Razik H.
name: Hussein, Jihan
name: Mohamed, Nadia A.
name: El-Kashak, Walaa A.
name: Nardoni, Simona
name: Mancianti, Francesca
name: De Leo, Marinella
name: Pistelli, Luisa
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Manihot esculenta Crantz (Euphorbiaceae), known as cassava, is a widely cultivated plant, considered one of the main sources of food in the tropical and subtropical regions of Africa and Asia. The aim of the present study was the evaluation of the antioxidant and anti-inflammatory effects of cassava shoot aqueous extract (CSAE) on liver injury induced by paracetamol and investigation of its effect on hyperhomocysteinemia. CSAE was administered to male albino rats classified into seven groups: control, treated, and prophylactic groups. A significant reduction in liver enzymes, malondialdehyde, and homocysteine were observed when compared to the paracetamol group, together with an increase in paraoxonase-1. Histopathological and histochemical results indicated that CSAE effectively ameliorate these parameters. Two main flavonol glycosides, quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside, in addition to a minor myricetin 3-O-rutinoside, were identified in CSAE. CSAE showed a therapeutic potential against paracetamol-induced liver injury probably through antioxidant activity of its flavonol glycosides.
Four new pregnane glycosides from Gymnema latifolium and their α-glucosidase and α-amylase inhibitory activities
Creators: name: Yen, Duong Thi Hai
name: Trang, Do Thi
name: Tai, Bui Huu
name: Van Doan, Vu
name: Yen, Pham Hai
name: Nhiem, Nguyen Xuan
name: Van Minh, Chau
name: Duc, Manh Hoang
name: Park, SeonJu
name: Lee, Jae Hyuk
name: Kim, Sun Yeou
name: Kim, Seung Hyun
name: Van Kiem, Phan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Four new pregnane glycosides, gymlatifosides A - D (1 − 4) and one known pregnane glycoside, verticilloside J (5) were isolated from the leaves of Gymnema latifolium Wall. ex Wight. Their chemical structures were elucidated on the basis of extensive spectroscopic methods, including 1D, 2D NMR, HR-ESI-MS, and in comparison with the reported data. All these compounds were tested for α-glucosidase and α-amylase inhibitory activities. Compound 5 exhibited the most anti α-glucosidase activity with inhibitory percentage of 37.8 ± 1.5% at the concentration of 200 μM. Compounds 1–4 showed moderate anti α-glucosidase activity with inhibitory percentage ranging from 7.0 to 30.1%. In addition, all compounds 1–5 showed moderate/weak anti α-amylase activity in the investigated test.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.12.1967, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.12.1967, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
The Role of Extrastriate Feedback in Contextual Computations iin the Primate Visual Cortex
Creators: name: Shushruth, S.
Publisher: name: University of Utah
Year: 2014

description: The primary visual cortex (V1) receives feedback projections from extrastriate visual cortical areas of a magnitude comparable to the feedforward projections it sends to them. Classically, this input has been thought to subserve "top-down" cognitive functions such as visual attention. Recently, it has been suggested that feedback could play role in more basic computations like surround modulation - the modulation of neuronal response by stimuli outside its receptive field (RF). The neural circuits and mechanisms generating such modulation remain unknown. A guiding hypothesis of this work is that feedback connections play an important role in this contextual computation. Using single unit electrophysiological recordings we have investigated the modulatory effects arising from the surround region of V1 neurons thought to be subserved by feedback connections, a region we term the ‘far' surround. We find that such modulation can be very specifically influence the response of the neuron to a stimulus inside its RF. First, by recording V1 neuron responses to an optimally oriented grating inside the neuron's RF while changing the orientation of a grating in the surround, we find that far-surround modulation is orientation-tuned, suggesting orientation specificity of the feedback connections themselves. Second, using grating stimuli confined to the ‘near' or ‘far' surround region, we find that the far surround is more broadly orientation-tuned than the near surround, perhaps indicating lesser specificity of feedback than horizontal connections. Third, using center and surround iv gratings both changing in orientation, we find that the surround is tuned to the stimulus presented to the V1 cells' receptive field, rather than to the neuron's preferred orientation. Specifically, the response of the neuron becomes maximally suppressed when the stimuli in the center and the surround are of the same orientation, irrespective of the preferred orientation of the neuron, and becomes less suppressed as the orientation difference increases, switching to facilitation in some instances. Thus, V1 neurons adapt their response to represent the orientation difference between the stimuli in the RF and the surround, and this is true across the range of the neuron's orientation tuning curve. Using computational modeling, we find that this mechanism can emerge from the dynamic interaction of orientation-specific horizontal and/or feedback connections with strong local recurrent connections. We suggest that such a mechanism may serve to enhance V1 responses to local orientation contrast, therefore increasing visual target saliency.
Enhancing transportation safety and security: a spatial multilevel approach
Creators: name: Przybyla, Jay J.
Publisher: name: University of Utah
Year: 2014
Subjects: Distracted driving
Nuclear
Planning
Safety
Transportation

description: A safe and secure transportation system is critical to providing protection to those who employ it. Safety is being increasingly demanded within the transportation system and transportation facilities and services will need to adapt to change to provide it. This dissertation provides innovate methodologies to identify current shortcomings and provide theoretic frameworks for enhancing the safety and security of the transportation network. This dissertation is designed to provide multilevel enhanced safety and security within the transportation network by providing methodologies to identify, monitor, and control major hazards associated within the transportation network. The risks specifically addressed are: (1) enhancing nuclear materials sensor networks to better deter and interdict smugglers, (2) use game theory as an interdiction model to design better sensor networks and forensically track smugglers, (3) incorporate safety into regional transportation planning to provide decision-makers a basis for choosing safety design alternatives, and (4) use a simplified car-following model that can incorporate errors to predict situational-dependent safety effects of distracted driving in an ITS infrastructure to deploy live-saving countermeasures.
title: Sechste Änderung der Finanz- und Haushaltsordnung der Studierendenschaft der Universität Paderborn
title: vom 30. September 2020
titleType: Subtitle
Creators: name: Universität Paderborn
Publisher: name: UB-PAD - Paderborn University Library
Year: 2020

description: Amtliche Mitteilungen / Universität Paderborn
Sonnenfleckenzeichnung Nr. 22618.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.09.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Opportunities for near data computing in mapreduce workloads
Creators: name: Pugsley, Seth Hintze
Publisher: name: University of Utah
Year: 2015
Subjects: Big data
Computer architecture
Hardware accelerators
Memory systems

description: In-memory big data applications are growing in popularity, including in-memory versions of the MapReduce framework. The move away from disk-based datasets shifts the performance bottleneck from slow disk accesses to memory bandwidth. MapReduce is a data-parallel application, and is therefore amenable to being executed on as many parallel processors as possible, with each processor requiring high amounts of memory bandwidth. We propose using Near Data Computing (NDC) as a means to develop systems that are optimized for in-memory MapReduce workloads, offering high compute parallelism and even higher memory bandwidth. This dissertation explores three different implementations and styles of NDC to improve MapReduce execution. First, we use 3D-stacked memory+logic devices to process the Map phase on compute elements in close proximity to database splits. Second, we attempt to replicate the performance characteristics of the 3D-stacked NDC using only commodity memory and inexpensive processors to improve performance of both Map and Reduce phases. Finally, we incorporate fixed-function hardware accelerators to improve sorting performance within the Map phase. This dissertation shows that it is possible to improve in-memory MapReduce performance by potentially two orders of magnitude by designing system and memory architectures that are specifically tailored to that end.
Functional investigation and applications of the acetylesterase activity of the Citrus sinensis (L.) Osbeck peel
Creators: name: Fontana, Gianfranco
name: Bruno, Maurizio
name: Maggio, Antonella
name: Rosselli, Sergio
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology

description: The hydrolysis of acetyl moieties on a set of commercially relevant substrates was performed by employing the whole tissue of Citrus sinensis (L.) Osbeck peel as an efficient biocatalyst in mild reaction conditions with high degree of regioselectivity. The reaction is done in aqueous media and the product is easily recovered. Optimal reaction conditions were deduced and two practical applications were investigated: the elaboration of acetylglicerols and the preparation of vitamin K1 precursor. Peel waste (flavedo and albedo) from orange juice manufacturing was successfully employed as a biocatalyst.
Additional file 1 of Absence of genetic isolation across highly fragmented landscape in the ant Temnothorax nigriceps
Creators: name: Cordonnier, Marion
name: Felten, Dominik
name: Trindl, Andreas
name: Heinze, Jürgen
name: Bernadou, Abel
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Ecology

description: Additional file 1. Additional tables and figures.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität nach einer Projektion vom 04.08.1967, erstellt von Max Waldmeier am Astrophysikalischen Observatorium Tschuggen in Arosa
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung am Astrophysikalischen Observatorium Tschuggen in Arosa. Instrument: Visuelles Objektiv an der Coelostatenanlage (15 cm Öffnung und 224 cm Brennweite, projiziertes Sonnenbild D = 25 cm). - Instrumentennachweis gemäss Tätigkeitsber. gedr. 1950 für das vorhergehende Jahr, S. 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt
Investigation of the pathogenesis of murine Lyme arthritis
Creators: name: Seiler, Kathleen Marie Petri
Publisher: name: University of Utah
Year: 2012
Subjects: Pathogenicity
Complications

description: Lyme disease is caused by the spirochete Borrelia burgdorferi and if left untreated, often causes arthritis. The spirochetes possess outer surface lipoproteins (Osps) that are capable of stimulating inflammatory cytokine production from B cells, macrophages, and endothelial cells, and the production of nitric oxide (NO). The role of NO during infection of mice with B. burgdorferi was investigated. Both the severely arthritic (C3H) and mildly arthritic (BALB/c) mice produced high levels of NO approximately 7 days after infection, but C3H animals rapidly downregulated NO production to background levels, whereas BALB/c animals sustained NO production throughout the course of infection. Complete inhibition of NO production by the compound N[G]-monomethyl-L-arginine (LMMA) during infection had no significant effect on either arthritis development or spirochete numbers in tissues. These results indicate that NO is ineffective at controlling spirochete numbers in tissues, and, therefore, B. burgdorferi probably does not require an intracellular localization for survival in the mammalian host. The reproducible downregulation of NO in C3H animals may be induced by anti-inflammatory cytokines which could modulate other aspects of the immune response to B. burgdorferi. In vitro studies showed that OspA could stimulate IL-10 production by naive murine splenocytes and that physiological concentrations of IL-10 could significantly downregulate the responses of OspA-treated macrophages. The inappropriate or uncontrolled production of IL-10 during infection could result in dysregulation of host defenses, thus leading to the development of pathology. The Osps also stimulate adhesion molecule expression on cells. The role of two adhesion molecules, E-selectin and P-selectin, in the development of Lyme arthritis, was investigated by infecting mice lacking both molecules with B. burgdorferi and assessing arthritis development and spirochete number. Mice lacking E- and P-selectin showed resistance to arthritis development and spirochete numbers virtually identical to their wild-type littermates, indicating that these adhesion molecules are not required for resistance to Lyme arthritis. Additionally, a correlation between influx of neutrophils into joints and arthritis severity was noted, indicating that neutrophil infiltration into joints may be required for the development of arthritis. These studies may aid in the determination of pathogenic mechanisms in Lyme arthritis.
The effects of the taped-problems time-delay intervention to teach sight words using an Ipod
Creators: name: Pummel, Mary Beth Lindsay
Publisher: name: University of Utah
Year: 2012
Subjects: Intervention
iPod
Reading
Sight words
Taped-problems
Time-delay

description: The current study is an extension of the research literature using time-delay taped-words intervention to teach sight words. An iPod Touch delivered the time-delay taped-words intervention to second grade students who had been identified as at risk for reading difficulties. This study utilized a response to intervention model in order to identify ad-risk students by screening an entire second grade using curriculum-based measurements. The intervention consisted of baseline, intervention, and maintenance phases. Data were collected to monitor student progress of learning sight words. In addition, generalization data were collected using measures of oral reading fluency. Data were analyzed by calculating percentage of nonoverlapping data points and effect sizes based on accuracy.
Sonnenfleckenzeichnung Nr. 22671.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.11.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen
Otitis media; compliance with the return appintment
Creators: name: Sehy, Yvonne Antoinette Browne
Publisher: name: University of Utah
Year: 2012
Subjects: Health Belief Model
Mothers' Demographic Characteristics

description: Mothers' compliance with recommended health actions for their children has typically been inadequate.  Numerous investigators have identified variables related to health behavior.  A theoretical formulation, the Health Belief Model, has been found predictive of compliance in a number of studies of low income pediatric populations.  Few strategies to improve compliance with health behaviors have been tested.  The sample consisted to 100 predominantly middle-class mothers with a child who was subsequently diagnosed with otitis media attending a private pediatric group practice.  The Health Belief Model was tested as a predictor of compliance, keeping the return appointment for otitis media.  In addition, three strategies for improving compliance were compared with a control group.  They included a reminder letter, an information sheet, and an educational discussion.  Sixty-five percent of the mothers kept the return appointment.  The mothers' perceived susceptibility for the ill child was the only major Health Belief Model component significantly related co compliance.  Several Health Belief Model modifying factors-mother's age and education, child's age, number of children at home and number of appointments made and kept in the past-were all significantly related to keeping the return appointment of otitis media.  The subjects receiving a mailed reminder letter had a significantly higher compliance rate for the return appointment than all other groups.  The findings suggest that the Health Belief Model may not be predictive to compliance in middle-class, private practice populations.  Development of a standardized set of questions made available for use in new investigations of the Health Belief Mode would allow more critical analysis of this theoretical framework. Mothers' demographic characteristics may be important predictor of health behavior and should be utilized in developing interventions for improving compliance.  More testing of both behavioral and educational intervention strategies is needed for various populations groups in different settings.
Sonnenfleckenzeichnung Nr. 22577.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.08.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.08.1967, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622
Phenolic compounds and antioxidant activity of Nepeta fissa - first report from Iran
Creators: name: Nasirkandi, Atefeh Moshari
name: Alirezalu, Abolfazl
name: Bahadori, Shahram
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Inorganic Chemistry
subject: Plant Biology

description: In recent years, scientific interest in natural products has burgeoned. The genus Nepeta is one of the most important medicinal plants belongs to family Lamiaceae. In this study, the total phenolic and flavonoid contents, antioxidant potential and distribution of individual phenolic compounds by HPLC-MS/MS were determined in native Nepeta fissa Benth species. The total phenolic and flavonoid contents and antioxidant capacity (by DPPH and FRAP assays) values were measured in N. fissa as 43.07 mg GAE/g dw, 3.77 mg q/g dw, 197.85 µg/mL (IC50 value) and 1.15 μmol Fe++/g dw, respectively. The most abundant flavonoid, phenolic acid, and anthraquinone in the analyzed N. fissa extracts were rutin, ferulic acid, and chrysophanol, respectively. As a conclusion, results of present study showed that N. fissa was rich in some phenolic compounds and exhibited antioxidant activity. The obtained results can provide new safe resources to the development of new products for the pharmaceutical industries.
Evaluation of different methods used in applying Bayes' rule to medical decision making
Creators: name: Barlow, Gary Keith
Publisher: name: University of Utah
Year: 2012
Subjects: Computer-Assisted
Software
Bayes' Equation

description: The computer is often used as a tool for medical decision-making.  One of the common methods used in computer diagnosis consists of using Bayes' equation to determine the probability of a patient having a disease.  One step in this procedure consists of determining the probability distribution of each laboratory test.  This distribution is usually expressed in the form of a histogram, in order to obtain the probability values need for Bayes' equation.  In order to reduce errors introduced by using histograms, a method has been developed to obtain a continuous curve.  This methods uses a mathematical model to obtain a curve approximating the distribution curve.  An evaluation of this method has been conducted using two separate studies.  The overall results indicate that the model does provide a good representation of the laboratory data.  The results for the continuous curve method are comparable with the other methods, however, and do not show a consistent improvement.  The two studies used in testing the different methods have also been evaluated to determine their usefulness in a clinical setting.  Both studies consist of methods of evaluating laboratory data.  The first study is a method of diagnosing myocardial infarction and produces results that indicate it may be useful in a clinical setting.  The second study determines the reliability of an abnormal creatinine result.  In this case the results may not be reliable enough for clinical use.