cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of nuclear substrates of Akt/PKB by functional proteomics: prohibitin 2 is a target of Akt phosphorylation in human promyelocytic leukemia cells
Creators: name: Bavelloni, Alberto
name: Faenza, Irene
name: Piazzi, Manuela
name: Blalock, William
name: D’Angelo, Antonietta
name: Tagliavini, Francesca
name: Pinetti, Diego
name: Matteucci, Sandro
name: Mariani, Giulia Adalgisa
name: Cocco, Lucio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: topography; nucleus; Akt; leukemia; functional protemics

description: The serine/threonine protein kinase Akt is a major signal transducer of the phosphoinositide 3-kinase (PI 3-K) pathway in all cells and tissues and plays a pivotal role in the maintenance of cellular processes including cell growth, proliferation, survival, metabolism and development of many malignancies including acute myeloid leukemia. The frequent aberrant activation of the PI 3-K/Akt pathway in human cancer has made it an attractive therapeutic target. Therefore, the study of effector proteins downstream of Akt could clarify the role of Akt in the development of myeloid leukemia. Although both localization and activity of Akt in the nuclear compartment are well documented, most Akt substrates identified so far are located in the cytoplasm, while nuclear substrates have remained elusive. In this study, we applied a proteomic approach to identify novel Akt substrates by using an antibody that recognized a consensus motif phosphorylated by Akt (K/RXK/RXXS/T) when phosphorylated on S/T (anti-phospho-Akt substrate antibody). NB4 cells were treated with ATRA, and the putative Akt substrate proteins were isolated by immunoprecipitation with the anti-phospho-Akt substrate antibody. The proteins were separated on SDS-PAGE and analyzed by ESI-Q-TOF mass spectrometry. This analysis indicated prohibitin 2, a potential tumor suppressor protein with potent transcriptional functions in the nucleus, as a putative substrate of Akt in the nucleus of NB4 cells. The putative Akt-Prohibitin 2 interaction was validated by reverse in vivo immunoprecipitation from nuclear protein of NB4 cells. In vitro phosphorylation of endogenous prohibitin 2 by recombinant Akt further validated this result. Vandermoere F, El Yazidi-Belkoura I, Demont Y, Slomianny C, Antol J, Lemoine J, Hondermarck H. Proteomics exploration reveals that actin is a signaling target of the kinase Akt. Mol Cell Proteomics. 2007 Jan;6(1):114-24. Kasashima K, Ohta E, Kagawa Y, Endo H. Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2. J Biol Chem. 2006 Nov 24;281(47):36401-10.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
title: ÐÐµÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ ÑÐ°ÑÑÐµÑÐ° ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÑ ÑÑÐµÐ½ÐºÐ¸ ÑÐ²ÑÐ»Ð° Ð¿ÑÐ¸ Ð¾Ð±ÑÐ°ÑÐµÐ½Ð½Ð¾Ð¼ ÐºÐ¾Ð»ÑÑÐµÐ²Ð¾Ð¼ ÑÐµÐ¶Ð¸Ð¼Ðµ ÑÐµÑÐµÐ½Ð¸Ñ Ð¿Ð°ÑÐ¾Ð²Ð¾Ð´ÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾ÑÐ¾ÐºÐ°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸ÑÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð¹Ð½ÑÑÐ´Ð¸Ð½Ð¾Ð², Ð ÑÑÐ»Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð²ÐµÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ
ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÐ° ÑÑÐµÐ½ÐºÐ¸
Ð°Ð²Ð°ÑÐ¸Ð¹Ð½ÑÐµ ÑÐµÐ¶Ð¸Ð¼Ñ
Ð¾Ð±ÑÐ°ÑÐµÐ½Ð½ÑÐ¹ ÐºÐ¾Ð»ÑÑÐµÐ²Ð¾Ð¹ ÑÐµÐ¶Ð¸Ð¼ ÑÐµÑÐµÐ½Ð¸Ñ
ÑÐµÐ¿Ð»Ð¾Ð¾Ð±Ð¼ÐµÐ½
Ð³Ð¸Ð´ÑÐ¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ°
ÐÐÐ Ð¡ÐÐ

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð° Ð²ÐµÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ° ÑÐ°ÑÑÑÑÐ° ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÑ ÑÑÐµÐ½ÐºÐ¸ ÑÐ²ÑÐ»Ð° Ð¿ÑÐ¸ Ð¾Ð±ÑÐ°ÑÐµÐ½Ð½Ð¾Ð¼ ÐºÐ¾Ð»ÑÑÐµÐ²Ð¾Ð¼ ÑÐµÐ¶Ð¸Ð¼Ðµ ÑÐµÑÐµÐ½Ð¸Ñ Ð¿Ð°ÑÐ¾Ð²Ð¾Ð´ÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾ÑÐ¾ÐºÐ°. ÐÐ¾Ð»ÑÑÐµÐ½Ð½ÑÐµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð² Ð Ð ÐÐÐ Ð¡ÐÐ  ÑÐ¾Ð¿Ð¾ÑÑÐ°Ð²Ð»ÐµÐ½Ñ Ñ Ð¾Ð¿ÑÑÐ½ÑÐ¼Ð¸ Ð´Ð°Ð½Ð½ÑÐ¼Ð¸ Ð¸Ð· ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ° Ð. ÐÐ¾ÑÐ°Ð½Ð½ÑÐ¾Ð½Ð° Ð¸ Ð. ÐÐ¾ÑÐ°Ð°Ð´Ð°. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð²ÑÑÐ²Ð»ÐµÐ½Ð° Ð½ÐµÐºÐ¾ÑÑÐµÐºÑÐ½Ð¾ÑÑÑ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ñ Ð¿ÑÐ¸ ÑÐ°ÑÑÑÑÐµ ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÑ ÑÑÐµÐ½ÐºÐ¸ ÐºÐ°Ð½Ð°Ð»Ð°.
A Comprehensive Analysis of WASP-17b's Transmission Spectrum from Space-Based Observations
Creators: name: Alderson, L.
name: Wakeford, H. R.
name: MacDonald, R. J.
name: Lewis, N. K.
name: May, E. M.
name: Grant, D.
name: Sing, D. K.
name: Stevenson, K. B.
name: Fowler, J.
name: Goyal, J.
name: Batalha, N. E.
name: Kataria, T.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Due to its 1770 K equilibrium temperature, WASP-17b, a 1.99 $R_\mathrm{Jup}$, 0.486 $M_\mathrm{Jup}$ exoplanet, sits at the critical juncture between hot and ultra-hot Jupiters. We present its 0.3-5 $μm$ transmission spectrum, with newly obtained with Hubble Space Telescope (HST) Wide Field Camera 3 (WFC3) measurements, and, taking advantage of improved analysis techniques, reanalysed HST Space Telescope Imaging Spectrograph (STIS) and Spitzer Space Telescope Infrared Array Camera (IRAC) observations. We achieve a median precision of 132 ppm, with a mean of 272 ppm across the whole spectrum. We additionally make use of Transiting Exoplanet Survey Satellite (TESS) and ground-based transit observations to refine the orbital period of WASP-17b. To interpret the observed atmosphere, we make use of free and equilibrium chemistry retrievals using the POSEIDON and ATMO retrieval codes respectively. We detect absorption due to H$_2$O at $>7 σ$, and find evidence of absorption due to CO$_2$ at $>3 σ$. We see no evidence of previously detected Na and K absorption. Across an extensive suite of retrieval configurations, we find the data favours a bimodal solution with high or low metallicity modes as a result of poor constraints in the optical, and demonstrate the importance of using multiple statistics for model selection. Future James Webb Space Telescope (JWST) GTO observations, combined with the presented transmission spectrum, will enable precise constraints on WASP-17b's atmosphere.
description: 25 pages, 13 figures, 10 tables. Accepted for publication in MNRAS
On-chip nano-manipulation of magnetic particles via domain walls conduits
Creators: name: Vavassori, P.
name: Gobbi, M.
name: Donolato, M.
name: Metlushko, V.
name: Ilic, B.
name: Cantoni, M.
name: Petti, D.
name: Brivio, S.
name: Bertacco, R.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The manipulation of geometrically constrained magnetic domain walls (DWs) in nanoscale magnetic strips has attracted much interest recently, with proposals for prospective memory and logic devices. Here we propose to use the high controllability of the motion of geometrically constrained DWs for the manipulation of individual nanoparticles on a chip with an active control of position at the nanometer scale. The proposed method exploits the fact that magnetic nanoparticles in solution can be captured by a DW, whose position can be manipulated with nanometric accuracy in a specifically designed magnetic nanowire structure. We show that the high control over DW nucleation, displacement, and annihilation processes in such structures can be used to capture, transport and release magnetic nanoparticles. As magnetic particles with functionalized surfaces are commonly used as molecule labels in several applications - including single molecule manipulation, separation, cells manipulation and biomagnetic sensing, the accurate control over the handling of the single magnetic nanoparticles becomes crucial as it may reflect the handling of the single molecules. The approach described here opens the path to the implementation and design of nano-transport lines, with application to single molecule study and lab-on-chip devices. In perspective, the easy integration on chip with sensors of domain walls and particles will allow for the realization of programmable circuits for molecular manipulation with continuous control of the desired process.
Toll-like receptor-4 expression by hepatic progenitor cells and biliary epithelial cells in HCV-related chronic liver disease
Creators: name: Carotti, Simone
name: Vespasiani-Gentilucci, Umberto
name: Onetti-Muda, Andrea
name: Latasa, Maria Ujue
name: Avila, Matias A.
name: Carpino, Guido
name: Picardi, Antonio
name: Morini, Sergio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: biliary epithelial cells; fibrosis; hepatic progenitor cells; hepatic stellate cells; inflammation; toll-like receptor-4

description: Background. Toll-like receptor-4 (TLR4) is a transmembrane pattern recognition receptor that plays a key role in innate immunity by triggering inflammatory responses to Gram negative bacteria lipopolysaccharide (LPS) (1). Since liver is the main clearance organ for LPS, which is excreted in large amounts in the bile (2), it is not surprising that TLR4 has been involved in the pathogenesis of most liver diseases (3). Numerous evidences suggest a role for TLR4 in the pathogenesis of chronic hepatitis C virus (HCV) infection (4) and hepatic fibrosis (5), but the localization and level of TLR4 expression in the liver of patients with hepatitis C have never been investigated. Aim and methods. We aimed to evaluate, by means of immunohistochemistry (IHC) and real-time polymerase chain reaction (rt-PCR), hepatic TLR4 expression in patients with chronic HCV infection. Sixty-one patients with chronic HCV infection, and 12 controls free of liver disease, were included in the study. Each case was analyzed by IHC for TLR4, α–smooth muscle actin (αSMA) and cytokeratin-7 (CK-7), and a subgroup of patients and all controls by rt-PCR for TLR4. A score of activation of portal/septal myofibroblasts and lobular hepatic stellate cells (HSCs) was evaluated by IHC for α-SMA, whereas IHC for CK-7 was analysed in order to count hepatic progenitor cells (HPCs), interlobular bile ducts and intermediate hepatocytes. Results. The parenchimal elements responsible for the highest TLR4 level of expression were HPCs and biliary epithelial cells (BECs) of interlobular bile ducts in the infected group. Double-labeling experiments with anti-TLR4, anti-CK7 and anti-CD133 confirmed this finding. TLR4-positive HPCs and interlobular bile ducts were significantly correlated with the stage of liver disease (p<0.001), the grade of inflammation (p<0.001), and with the activity of portal/septal myofibroblasts (p<0.001). Rt-PCR study confirmed an increased TLR4 expression in the 26 patients analyzed with respect to controls (p<0.001). TLR4 expression positively correlated with fibrosis (p<0.05) and inflammation (p<0.05). Conclusions. The expression of TLR4 in HPCs and BECs in HCV-related liver damage significantly correlates with inflammation, activation of portal/septal myofibroblasts and fibrosis. 1) Beutler. Nature 2004;430:257-63; 2) Van Bossuyt et al. J Hepatol 1988;7:325-37; 3) Seki et al. Hepatology 2008;48:322-35; 4) Machida et al. J Virol 2006;80:866-74. 5) Seki et al. Nat Med 2007;13:1324-32.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Additional file 2 of Incentive delivery timing and follow-up survey completion in a prospective cohort study of injured children: a randomized experiment comparing prepaid and postpaid incentives
Creators: name: Millar, Morgan M.
name: Olson, Lenora M.
name: VanBuren, John M.
name: Richards, Rachel
name: Pollack, Murray M.
name: Holubkov, Richard
name: Berg, Robert A.
name: Carcillo, Joseph A.
name: McQuillen, Patrick S.
name: Meert, Kathleen L.
name: Mourani, Peter M.
name: Burd, Randall S.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 2. Children’s injury information, overall study sample and by experimental arm
title: [Ð Ð¿ÑÐ¸ÑÐ²Ð¾ÐµÐ½Ð¸Ð¸ ÐÐ¾Ð»Ð¸ÑÐµÑ Ð½Ð¸ÑÐµÑÐºÐ¾Ð¼Ñ Ð¸Ð½ÑÑÐ¸ÑÑÑÑ Ð¸Ð¼ÐµÐ½Ð¸ Ð¸Ð¼Ð¿ÐµÑÐ°ÑÐ¾ÑÐ° ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾]
title: ÑÐ½Ð²Ð°ÑÑ 1910 Ð³Ð¾Ð´Ð°, â 52950
titleType: Subtitle
Creators: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½ÑÐ¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑ Ð½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 1910

description: ÐÑÑÐ¾ÑÐ°Ð¹ÑÐµÐµ Ð¿Ð¾Ð²ÐµÐ»ÐµÐ½Ð¸Ðµ, Ð¾Ð±ÑÑÐ²Ð»ÐµÐ½Ð½Ð¾Ðµ Ð¼Ð¸Ð½Ð¸ÑÑÑÐ¾Ð¼ ÑÐ¾ÑÐ³Ð¾Ð²Ð»Ð¸ Ð¸ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¡. Ð. Ð¢Ð¸Ð¼Ð°ÑÐµÐ²ÑÐ¼ Ð¾ Ð¿ÑÐ¸ÑÐ²Ð¾ÐµÐ½Ð¸Ð¸ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð¼Ñ Ð¸Ð½ÑÑÐ¸ÑÑÑÑ Ð¸Ð¼ÐµÐ½Ð¸ Ð¸Ð¼Ð¿ÐµÑÐ°ÑÐ¾ÑÐ° ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾.
Sharp Bounds for Sums Associated to Graphs of Matrices
Creators: name: Mingo, James A.
name: Speicher, Roland
Publisher: name: arXiv
Year: 2009
Subjects: subject: Operator Algebras (math.OA)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C90, 62E20

description: We provide a simple algorithm for finding the optimal upper bound for sums of products of matrix entries of the form S_pi(N) := sum_{j_1, ..., j_2m = 1}^N t^1_{j_1 j_2} t^2_{j_3 j_4} ... t^m_{j_2m-1 j_2m} where some of the summation indices are constrained to be equal. The upper bound is easily obtained from a graph G associated to the constraints in the sum.
description: 20 pages
Manitoba and Winnipeg market analysis : an economic overview and office & industrial market analysis
Creators: name: Karu, Chris
Publisher: name: The University of British Columbia
Year: 2016

description: Great West Life Realty Advisors, as a wholly owned subsidiary of The Great-West Life Assurance Company, provides asset and property management, development and real estate advisory services on behalf of pension funds and institutional and retail investors. In 2014 GWL Realty Advisors managed 288 properties totalling $16.5 billion across Canada, with 246 (85%) of assets in Ontario, Alberta, Quebec and British Columbia valued at over $15.5 billion (93%).1 Real estate acquisition opportunities in secondary Canadian markets are becoming a focus for many institutional investors, as quality assets in core markets are becoming hard to find due to increased demand for real estate and rising asset prices. GWL Realty Advisors views Winnipeg as a potential investment destination and thus initiated this economic and real estate market overview focusing on office and industrial properties. This report is a summation of the Portfolio Analysis and Research Services department’s review of Winnipeg and Manitoba’s key economic indicators and office and industrial markets.
Additional file 3 of Incentive delivery timing and follow-up survey completion in a prospective cohort study of injured children: a randomized experiment comparing prepaid and postpaid incentives
Creators: name: Millar, Morgan M.
name: Olson, Lenora M.
name: VanBuren, John M.
name: Richards, Rachel
name: Pollack, Murray M.
name: Holubkov, Richard
name: Berg, Robert A.
name: Carcillo, Joseph A.
name: McQuillen, Patrick S.
name: Meert, Kathleen L.
name: Mourani, Peter M.
name: Burd, Randall S.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 3. Demographics by follow-up survey completion status and experimental arm
$ϕ^4$ inflation is not excluded
Creators: name: Ramirez, Erandy
name: Schwarz, Dominik J.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present counter examples to the claim that the $λϕ^4$ inflaton potential is excluded by recent cosmological data. Finding counter examples requires that the actually observed primordial fluctuations are generated at the onset of the slow-roll regime of inflation. This set up for the initial conditions is therefore different from the usual scenario of chaotic inflation where inflation starts long before the observed fluctuations are created. The primordial power spectrum of "just enough" chaotic inflation violates scale-invariance in a way consistent with observations.
description: Extended motivation, matches published version in Phys. Rev. D
Analytical description of stationary ideal MHD flows with constant total pressure
Creators: name: Golovin, Sergey V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 76W05

description: Incompressible stationary flows of ideal plasma are observed. By introduction of curvilinear system of coordinates in which streamlines and magnetic force lines form a family of coordinate surfaces, MHD equations are partially integrated and brought to a certain convenient form. It is demonstrated that the admissible group of Bogoyavlenskij's symmetry transformations performs as a scaling transformation for the curvilinear coordinates. Analytic description of stationary flows with constant total pressure is given. It is shown, that contact magnetic surfaces of such flows are translational surfaces, i.e. are swept out by translating one curve rigidly along another curve. Explicit examples of solutions with constant total pressure possessing a significant functional arbitrariness are given.
Strong cohomological rigidity of a product of projective spaces
Creators: name: Choi, Suyoung
name: Suh, Dong Youp
Publisher: name: arXiv
Year: 2009
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 57S25 (Primary) 22F30 (Secondary)

description: We prove that for a toric manifold $M$, any graded ring isomorphism $H^\ast(M) \to H^\ast(\prod_{i=1}^{m}\CP^{n_i})$ is induced by a diffeomorphism $\prod_{i=1}^m \CP^{n_i} \to M$.
Additional file 1 of Egg consumption reduces the risk of depressive symptoms in the elderly: findings from a 6-year cohort study
Creators: name: Li, Fudong
name: Li, Xiaoli
name: Gu, Xue
name: Zhang, Tao
name: Xu, Le
name: Lin, Junfen
name: Chen, Kun
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Additional file 1: Table S1. Baseline characteristics of 8289 included participants according to egg consumption.
title: ÐÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Ð°Ð²ÑÐ¾ÑÑÐºÐ¾Ð¹ ÐºÑÑ Ð½Ð¸ Ð½Ð° 75 Ð¼ÐµÑÑ Ð² Ð¦ÐµÐ½ÑÑÐ°Ð»ÑÐ½Ð¾Ð¼ ÑÐ°Ð¹Ð¾Ð½Ðµ Ð³. Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¸ÑÐ°Ð³Ð¾ÑÑÐºÐ°Ñ, ÐÐ»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÐµÑÑÐ¾ÑÐ°Ð½
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Ð°Ð²ÑÐ¾ÑÑÐºÐ°Ñ ÐºÑÑ Ð½Ñ

description: ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¾ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ðµ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Ð°Ð²ÑÐ¾ÑÑÐºÐ¾Ð¹ ÐºÑÑÐ½Ð¸, Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ°ÑÑÑÑÑ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÑÑÑÐºÑÑÑÐ° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÑÐµÐ¼Ð¾Ð³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ, ÐµÐ³Ð¾ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð¾ÑÐ½Ð¾Ðµ ÑÐµÑÐµÐ½Ð¸Ðµ Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸.
Young hearts in Chinatown = 青心在唐人街 : Activating Public Space in Vancouver’s Chinatown
Creators: name: Lennon, Kathryn Gwun-Yeen
Publisher: name: The University of British Columbia
Year: 2017

description: Over the summer of 2015, the Youth Collaborative for Chinatown worked to activate public spaces in Vancouver’s Chinatown in an intergenerational, intercultural manner through a series of events: the “Hot and Noisy” (熱鬧) Chinatown Mahjong Socials. On the surface, our goal was simple: to bring back Chinatown’s 熱鬧, or “yeet low” in Cantonese, – literally, “hot and noisy”, or liveliness and energy. Below the surface, we had more complex goals of being able to bring a youth voice to planning processes about the future of Chinatown, and building up political and social capacity of young generations of Chinese Canadians. We decided that our approach to activating public space had several criteria. It needed to be visible. It needed to be collaborative. It needed to demonstrate a cohesive, coordinated effort undertaken by younger generations, with the ability to involve many others. It needed to be intercultural and multilingual. It needed to foster relationships between young and old. It needed to be feasible to implement within a very short time frame. It needed to involve no to low hard costs. And it needed to be possible with the resources and skills we could readily bring to the table, amongst our team of organizers. By temporarily activating a public space, there is an opportunity to both share and transform the stories that we tell ourselves and each other in relation to it, and to create spaces of belonging. Based on participant observation/action as a member of the Youth Collaborative for Chinatown, I describe the “Hot and Noisy” (熱鬧) Chinatown Mahjong Socials as a case study of a youth-driven, grassroots process in public space activation. I discuss lessons learned and the implications for planning, urban design and community organizing.
Periosteal derived cells and bone tissue regenerative medicine
Creators: name: Mattioli-Belmonte, Monica
name: Ferretti, Concetta
name: Gentile, Piergiorgio
name: Orciani, Monia
name: Borsari, Veronica
name: Di Primio, Roberto
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: periosteal precursor; stem cells; bone tissue; biomaterials

description: Mesenchymal stem cells (MSCs), showing a high capacity of self-renewal and differentiation into various lineages, have primarily used for the biological repair of cartilage and bone. Even though MSCs have been identified in different organ tissues, cells from different sources may show phenotypic heterogeneity, different in vivo results and specific functions of graft regions after transplantation. Therefore, a correct selection of MSC source is crucial to obtain a more efficient treatment for regeneration of injured osteochondral tissues. Periosteum Derived Progenitor Cells (PDPCs), which possesses multipotency at single cell level and can form cartilage and bone in vitro and in vivo may represent as an interesting cell resource for bone tissue engineering. Aim of the present study is the isolation and characterization of human PDPCs and the evaluation of their ability to grow on bioresorbable composite scaffolds for bone tissue engineering applications. PDCPs were obtained from periosteal tissue harvested from healthy subjects undergoing surgery for orthopedic trauma. Prior to cells seeding cell were phenotipically characterized. Three composite scaffolds, differing in weight ratios between the components were tested. The scaffolds were coded as CEL2/POL 0/100, 40/60 and 70/30 where CEL2 is a bioglass and POL the organic component based on chitosan and gelatin. Cells were cultured for 14 and 21 days. Our culture conditions favour the selection of a mesenchymal stem cells population. The obtained PDPCs displayed a good ability to interact with the different tested scaffolds. Morphological and biochemical analysis performed showed that cells maintain their metabolic activity and ability to proliferate on the scaffolds. Differentiation over proliferation that occurred to PDCPs at the increase of bioactive glass concentration proves the capacity of these scaffolds to modulate osteogenic properties. This strengthens the hypothesis of periosteum as stem cell source for an osteochondral tissue regenerative medicine based on in situ cell recruitment.  This work was supported by RBAP10MLK7 FIRB project.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Properties of the Be-type stars in 30 Doradus
Creators: name: Dufton, P. L.
name: Lennon, D. J.
name: Villasenor, J. I.
name: Howarth, I. D.
name: Evans, C. J.
name: de Mink, S. E.
name: Sana, H.
name: Taylor, W. D.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The evolutionary status of Be-type stars remains unclear, with both single-star and binary pathways having been proposed. Here, VFTS spectroscopy of 73 Be-type stars, in the spectral-type range, B0--B3, is analysed to estimate projected rotational velocities, radial velocities and stellar parameters. They are found to be rotating faster than the corresponding VFTS B-type sample but simulations imply that their projected rotational velocities are inconsistent with them all rotating at near critical velocities. The de-convolution of the projected rotational velocities estimates leads to a mean rotational velocity estimate of 320-350 km/s, approximately 100 km/s larger than that for the corresponding B-type sample. There is a dearth of targets with rotational velocities less than 0.4 of the critical velocity, with a broad distribution reaching up to critical rotation. Our best estimate for the mean or median of the rotational velocitiy is 0.68 of the critical velocity. Rapidly-rotating B-type stars are more numerous than their Be-type counterparts, whilst the observed frequency of Be-type stars identified as binary systems is significantly lower than that for normal B-type stars, consistent with their respective radial-velocity dispersions. The semi-amplitudes for the Be-type binaries are also smaller. Similar results are found for a SMC Be-type sample centred on NGC346 with no significant differences being found between the two samples. These results are compared with the predictions of single and binary stellar evolutionary models for Be-type stars. Assuming that a single mechanism dominated the production of classical Be-type stars, our comparison would favour a binary evolutionary history.
description: Accepted for publication in MNRAS, Appendicesand Tables 2 and 4 published as supplementary material
title: ÐÐ¾Ð²ÑÑÐµÐ½Ð¸Ðµ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÑÐ°Ð±Ð¾ÑÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð² ÑÐ¸ÑÑÐµÐ¼Ð°Ñ Ð¿ÑÐ¾Ð¼ÐµÐ¶ÑÑÐ¾ÑÐ½Ð¾Ð¹ ÑÐµÐ¿Ð°ÑÐ°ÑÐ¸Ð¸ Ð¸ Ð¿ÐµÑÐµÐ³ÑÐµÐ²Ð° ÑÑÑÐ±Ð¸Ð½ ÐÐ­Ð¡
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: Ð¨Ð¼Ð°ÐºÐ¾Ð²Ð°, ÐÐ½Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÐÐ°ÑÐ¾Ð¿ÐµÑÐµÐ³ÑÐµÐ²Ð°ÑÐµÐ»Ð¸
ÐÐ°ÑÐ¾Ð²ÑÐµ ÐºÐ¾ÑÐ»Ñ
ÐÑÐ¾Ð¼Ð½ÑÐµ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÑÐ°Ð½ÑÐ¸Ð¸

description: Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ Ð¾Ð±Ð·Ð¾Ñ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ñ Ð¾ÑÐµÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ Ð¡ÐÐ, Ð¸Ñ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ Ð¸ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿ ÑÐ°Ð±Ð¾ÑÑ. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ, Ð²Ð¾Ð·Ð½Ð¸ÐºÐ°ÑÑÐ¸Ðµ Ð¿ÑÐ¸ ÑÐ°Ð±Ð¾ÑÐµ Ð¡ÐÐ, ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¿ÑÑÐ¸ Ð¸Ñ ÑÐµÑÐµÐ½Ð¸Ñ Ð¿Ð¾ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐ½ÑÐ¼ Ð¸ÑÑÐ¾ÑÐ½Ð¸ÐºÐ°Ð¼. ÐÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ ÑÐ°ÑÑÐµÑ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ ÑÐµÐ¿Ð»Ð¾Ð²ÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº Ð¡ÐÐ-500-1, ÑÐ¸ÑÐ¾ÐºÐ¾ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·ÑÐµÐ¼ÑÑ Ð¿ÑÐ¸ ÑÐ°Ð±Ð¾ÑÐµ ÐÐ­Ð¡ Ñ ÑÐµÐ°ÐºÑÐ¾ÑÐ¾Ð¼ Ð±Ð¾Ð»ÑÑÐ¾Ð¹ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸ (Ð ÐÐÐ). ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ð¹ ÑÐ°Ð²Ð½Ð¾Ð²ÐµÑÐ½Ð¾Ð¹ ÑÐµÑÐ¼Ð¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð° Ð¼Ð¾Ð´ÐµÐ»Ñ ÑÐ°ÑÑÐµÑÐ° ÑÐ°Ð·Ð¼ÐµÑÐ¾Ð² ÐºÐ°Ð¿ÐµÐ»Ñ, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¿Ð¾Ð»Ð½Ð¾ÑÑÑÑ Ð¸ÑÐ¿Ð°ÑÑÑÑÑ, Ð¿ÑÐ¾Ð¹Ð´Ñ Ð¿ÐµÑÐ²ÑÑ ÑÑÑÐ¿ÐµÐ½Ñ Ð¿Ð°ÑÐ¾Ð¿ÐµÑÐµÐ³ÑÐµÐ²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð¹ ÑÐ°ÑÑÐ¸ Ð¡ÐÐ. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ Ð´Ð¸Ð°Ð¼ÐµÑÑÐ¾Ð² ÐºÐ°Ð¿ÐµÐ»Ñ, Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ð¹ ÑÐ°Ð²Ð½Ð¾Ð²ÐµÑÐ½Ð¾Ð¹ Ð¸ Ð½ÐµÑÐ°Ð²Ð½Ð¾Ð²ÐµÑÐ½Ð¾Ð¹ ÑÐµÑÐ¼Ð¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸. Ð Ð°ÑÑÐµÑ ÑÐ°Ð·Ð¼ÐµÑÐ° ÐºÐ°Ð¿ÐµÐ»Ñ, Ð¸ÑÐ¿Ð°ÑÐ¸Ð²ÑÐ¸ÑÑÑ Ð² Ð¿Ð°ÑÐ¾Ð¿ÐµÑÐµÐ³ÑÐµÐ²Ð°ÑÐµÐ»Ðµ, Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÐµÑ Ð¾ÑÐµÐ½Ð¸ÑÑ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÐ°Ð±Ð¾ÑÑ ÑÐµÐ¿Ð°ÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÑÑÑÐ¾Ð¹ÑÑÐ².
Additional file 3 of The risk of acute and early HIV (AEH) infection among MSM with different behaviour trajectories: an open cohort study in Tianjin, China, 2011–2019
Creators: name: Wang, Xiaomeng
name: Zhang, Tiantian
name: Chang, Qinxue
name: Wang, Chun
name: Wang, Keyun
name: Yu, Zeyang
name: Zhang, Honglu
name: Huang, Huijie
name: Song, Desheng
name: Peixoto, Elissa
name: Yang, Jie
name: Li, Changping
name: Cui, Zhuang
name: Liu, Yuanyuan
name: Ma, Jun
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 3. Flow chart and restricted cubic splines (RCS) chart.
Additional file 1 of Long-term outcome of postpartum psychosis: a prospective clinical cohort study in 106 women
Creators: name: Rommel, Anna-Sophie
name: Molenaar, Nina Maren
name: Gilden, Janneke
name: Kushner, Steven A.
name: Westerbeek, Nicola J.
name: Kamperman, Astrid M.
name: Bergink, Veerle
Publisher: name: figshare
Year: 2021
Subjects: subject: Cell Biology
subject: Biotechnology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1: Table A1. Baseline and clinical characteristics of the women lost to follow-up.
title: ÐÐ½Ð°Ð»Ð¸Ð· Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Ð-Ð¡ÑÑÐ¾Ð¹)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¾Ð½ÑÑÐ°Ð½ÑÐ¸Ð½Ð¾Ð²Ð°, Ð­Ð»ÑÐ¼Ð¸ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð°Ñ ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ
Ð²Ð½ÐµÑÐ½ÑÑ ÑÑÐµÐ´Ð°
Ð²Ð½ÑÑÑÐµÐ½Ð½ÑÑ ÑÑÐµÐ´Ð°
Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²ÑÐ¹ Ð±ÑÐ´Ð¶ÐµÑ
ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ°Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ

description: ÐÐ±ÑÐµÐºÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: ÐÐÐ Â«Ð-Ð¡ÑÑÐ¾Ð¹Â». Ð¦ÐµÐ»ÑÑ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ ÐÐÐ Â«Ð-Ð¡ÑÑÐ¾Ð¹Â» Ð´Ð»Ñ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ Ð²ÑÐ±ÑÐ°Ð½Ð½Ð¾Ð¹ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸. ÐÑÐ»Ð° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¾ÑÐ½Ð¾Ð² Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ ÐµÐµ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð²Ð¸Ð´Ñ Ð¸ Ð²ÑÐ´ÐµÐ»ÐµÐ½Ñ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸ÐµÐ¹ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ.
ÐÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²Ð¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹ ÐÐÐ Â«Ð-Ð¡ÑÑÐ¾Ð¹Â», Ð°Ð½Ð°Ð»Ð¸Ð· Ð²Ð½ÐµÑÐ½ÐµÐ¹ Ð¸ Ð²Ð½ÑÑÑÐµÐ½Ð½ÐµÐ¹ ÑÑÐµÐ´Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¼ÐµÑÐ¾Ð´Ð°Ð¼Ð¸ SWOT-Ð°Ð½Ð°Ð»Ð¸Ð·, SNW-Ð°Ð½Ð°Ð»Ð¸Ð· Ð¸ PEST-Ð°Ð½Ð°Ð»Ð¸Ð·. ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð³Ð»Ð°Ð²Ð½ÑÐµ ÐºÐ¾Ð½ÐºÑÑÐµÐ½ÑÑ Ð¸ Ð¿Ð¾ÑÑÐµÐ±Ð¸ÑÐµÐ»Ð¸ ÐÐÐ Â«Ð-Ð¡ÑÑÐ¾Ð¹Â». ÐÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð° Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð°Ñ ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ ÐÐÐ Â«Ð-Ð¡ÑÑÐ¾Ð¹Â», ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²ÑÐ¹ Ð±ÑÐ´Ð¶ÐµÑ Ð¸ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ°Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÐµÐºÐ»Ð°Ð¼Ñ.
ÐÑÐ»Ð¸ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ Ð¼ÐµÑÑ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸ ÐÐÐ Â«Ð-Ð¡ÑÑÐ¾Ð¹Â».
Additional file 1 of Effects of phantom exercises on pain, mobility, and quality of life among lower limb amputees; a randomized controlled trial
Creators: name: Zaheer, Anna
name: Malik, Arshad Nawaz
name: Masood, Tahir
name: Fatima, Sahar
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Cell Biology
Biotechnology
Developmental Biology
Science Policy

description: Additional file 1.
Clinical significance of immune-system laboratory tests
Creators: name: Ruggiero, Marco
name: Pacini, Stefania
name: Punzi, Tiziana
name: Morucci, Gabriele
name: Gulisano, Massimo
name: Koehnlein, Claus
name: Bauer, Henry H.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: HIV; AIDS; antibody; CD4

description: Anatomists and many other medical specialists rely on clinical laboratories for critical information to assist in diagnosis, prognosis, and the evaluation of treatments. However, the clinical laboratories do not always accompany their numbers with sufficient information about the significance of certain results: how great the quantitative variation of a given parameter might be in healthy subjects, and how likely it might be that a given qualitative (“yes” or “no”) result is a false positive or false negative. This situation has been particularly troublesome in the case of HIV, because there is no “gold standard” HIV test and the typically quantitated measure, CD4, varies widely for a variety of reasons that have nothing to do with HIV infection. For example, a person pronounced HIV-positive after having some vaccinations became HIV-negative again after a time, something that is not regarded as possible if HIV-positive denotes definitely active infection, as is commonly assumed. An important consequence of deficient information about HIV epidemiology is that students of anatomy may fear risking possible infection in dissection laboratories when the actual risk is negligible even in respect to anonymous cadavers in South Africa where the supposed incidence of HIV is particularly high. We have previously pointed to the need to improve HIV epidemiology and related public policy by recognizing and taking into account the weaknesses in HIV testing, which are the probable reason for at least some of the troubling conundrums and mutually contradictory data that seem inexplicable: conflicting estimates of HIV infections and of HIV-disease deaths from equally authoritative sources; apparently drastically different primary modes of transmission in different geographic regions; extreme racial disparities in HIV infection, with Asians and Asian Americans consistently less affected, by about one third, than white Americans, while black Americans are affected by as much as an order of magnitude more than white Americans. Testing uncertainties doubtless also contribute to the confusion as to whether certain conditions (e.g. lipodystrophy or nephropathy) should be described as HIV-associated or as AIDS-associated. In recent work we have found that the immune system, including CD4 counts, can be markedly enhanced by easily modified dietary supplementation that has none of the toxic side-effects of the antiretroviral drugs currently used in the attempt to elevate CD4 counts in HIV-positive people.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Traffic-driven Epidemic Spreading in Finite-size Scale-Free Networks
Creators: name: Meloni, S.
name: Arenas, A.
name: Moreno, Y.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: The study of complex networks sheds light on the relation between the structure and function of complex systems. One remarkable result is the absence of an epidemic threshold in infinite-size scale-free networks, which implies that any infection will perpetually propagate regardless of the spreading rate. The vast majority of current theoretical approaches assumes that infections are transmitted as a reaction process from nodes to all neighbors. Here we adopt a different perspective and show that the epidemic incidence is shaped by traffic flow conditions. Specifically, we consider the scenario in which epidemic pathways are defined and driven by flows. Through extensive numerical simulations and theoretical predictions, it is shown that the value of the epidemic threshold in scale-free networks depends directly on flow conditions, in particular on the first and second moments of the betweenness distribution given a routing protocol. We consider the scenarios in which the delivery capability of the nodes is bounded or unbounded. In both cases, the threshold values depend on the traffic and decrease as flow increases. Bounded delivery provokes the emergence of congestion, slowing down the spreading of the disease and setting a limit for the epidemic incidence. Our results provide a general conceptual framework to understand spreading processes on complex networks.
description: Final version to be published in Proceedings of the National Academy of Sciences USA
title: ÐÐ°ÑÑÑÐ¾Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð°ÑÐ¸Ñ ÐºÐ°Ðº ÑÐ°ÑÑÑ Ð¿ÑÐ±Ð»Ð¸ÑÐ½Ð¾Ð¹ Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð°ÑÐ¸Ð¸ Ð¨Ð²ÐµÑÐ¸Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð ÐµÑÐµÑÐ½Ð¸ÐºÐ¾Ð²Ð° , ÐÐ¾Ð»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¿ÑÐ±Ð»Ð¸ÑÐ½Ð°Ñ Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð°ÑÐ¸Ñ
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Ultrastructural and biochemical analysis of in vitro odontoblast differentiation
Creators: name: Salvatore, Viviana
name: Trirè, Alessandra
name: Gabriella, Teti
name: Pelotti, Susi
name: Falconi, Mirella
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: odontoblast like cells; differentiation; extracellular matrix protein; DMP1; collagen type I

description: The purpose of this study was to develop an in vitro model of odontoblast differentiation and dentin formation which allows to deeply and better study the process of odontoblast differentiation and protein matrix deposition and mineralization. Human dental pulp cells were obtained from extracted molar teeth of donors under informed consent. Cells were induced to odontoblast differentiation for 7, 14, 21 and 28 days by adding in the cell medium dexamethasone, β-glicerophosphate, ascorbic acid and TGF-β1. Alizarin red staining, electron microscopy, western blotting were carried out to demonstrate the odontoblast differentiation process, extracellular matrix deposition and mineralization. Alizarin red staining results showed a gradual calcium deposition during the treatment, reaching the highest signal at 28 days of stimulation. Electron microscopy demonstrated the deposition of fibrillar structures in the extracellular matrix, connected with extracellular matrix proteins. Western blotting analysis showed the expression of collagen type I and dentin matrix protein 1, markers for the odontoblast phenotype. The in vitro odontoblast differentiation model described if an highly repetitive model and it represents a potential and promising tool to explore the extracellular matrix deposition and mineralization process in physiological and pathological conditions.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011
Backgrounder – 2011 Canadian Research Data Summit
Creators: name: Research Data Canada
Publisher: name: Zenodo
Year: 2011
Subjects: Research Data Strategy, Canada

description: The 2011 Canadian Research Data Summit was held at the Ottawa Convention Centre on September 14. About the Summit
 On September 14-15, 2011, The 2011 Canadian Research Data Summit brings together 100-150 senior researchers, high level policy makers, university administrators, and members of the private sector. Together, participants will work on formulating a shared strategy for addressing the challenges and opportunities for maximizing the benefits of our collective investment in research data in Canada. The Summit will act as a catalyst for the development of a made-inCanada approach for maximizing the availability and use of research data.

 About the Research Data Strategy Working Group
 The Research Data Strategy Working Group is a collaborative effort launched in 2008 to address the challenges and issues surrounding the access and preservation of data arising from Canadian research. This multi-disciplinary group of universities, institutes, libraries, operators of research infrastructure, granting agencies, governments, and individual researchers are united through a shared recognition of the pressing need to deal with Canadian data stewardship issues. Together, they are focussing on the necessary actions, next steps and leadership roles that researchers and institutions can take to ensure Canada’s research data are accessible and usable for current and future generations of researchers
Persistent current in a mesoscopic cylinder: effects of radial magnetic field
Creators: name: Maiti, Santanu K.
name: Aeenehvand, F.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In this work, we study persistent current in a mesoscopic cylinder subjected to both longitudinal and transverse magnetic fluxes. A simple tight-binding model is used to describe the system, where all the calculations are performed exactly within the non-interacting electron picture. The current $I$ is investigated numerically concerning its dependence on total number of electrons $N_e$, system size $N$, longitudinal magnetic flux $ϕ_l$ and transverse magnetic flux $ϕ_t$. Quite interestingly we observe that typical current amplitude oscillates as a function of the transverse magnetic flux, associated with the energy-flux characteristics, showing $N ϕ_0$ flux-quantum periodicity, where $N$ and $ϕ_0$ $(=ch/e)$ correspond to the system size and the elementary flux-quantum respectively. This analysis may provide a new aspect of persistent current for multi-channel cylindrical systems in the presence of radial magnetic field $B_r$, associated with the flux $ϕ_t$.
description: 6 pages, 5 figures
Loss of spinal motor neurons and alteration of alpha-synuclein subcellular localization in MPTP induced parkinsonism in mice
Creators: name: Vivacqua, Giorgio
name: Biagioni, Francesca
name: Yu, Shun
name: Casini, Arianna
name: Bucci, Domenico
name: Fornai, Francesco
name: D’Este, Loredana
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2011
Subjects: Parkinson Disease; Amyotrophic Lateral Sclerosis; neurodegeneration; immunohistochemistry; spinal cord

description: 1-methyl, 4-phenyl, 1, 2, 3, 6-tetrahydropiridine (MPTP) is a neurotoxin, widely used to produce experimental models of Parkinson Disease in rodents and primates. Although dopaminergic neurons are the most sensitive to MPTP neurotoxicity, different neuronal subtypes could be affected. In particular, noradrenergic neurons of the Locus Coeruleus may be involved as well as nigral dopaminergic neurons. Moreover, apart from catecholamine-containing nuclei, recent studies indicate that MPTP may produce pathological effects within the spinal cord. This point deserves compelling interest since it suggests, at experimental level, commonalities between Parkinson Disease and Amyotrophic Lateral Sclerosis. For instance, recent reports demonstrate that MPTP activates apoptotic proteins at the level of spinal cord. However, to our knowledge, none of these studies so far analyzed whether motor neuron loss really occurs following MPTP administration. Therefore, in the present study we evaluated the effect of a robust dose of MPTP (20 mg/Kg X3) in the nigro-striatal system and spinal cord. Along with a severe dopaminergic cells loss within the substantia nigra, quantified by stereology and a marked decrease of striatal catecholoamine fibers measured by semi-quantitative densitometry, we found a significant (roughly 30 %) depletion of motor neurons in the lumbar spinal cord of MPTP-treated C57BL/6J mice. At the same level, spared motor neurons often present an altered morphology, being dysmorphic and vacuolated. Furthermore, using four different antibodies (tree monoclonal, one polyclonal), recognizing distinct epitopes in the sequence of alpha-synuclein, we found that alpha-synuclein immunostaining is markedly altered in the spinal cord of MPTP-treated mice. The present data shed new lights on similarities between dopaminergic neurons and spinal motor neurons, while suggesting that MPTP might be a neurotoxin diverse from what originally considered.
description: Italian Journal of Anatomy and Embryology, Vol 116, No 1 (Supplement) 2011