cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Toward the future community care: a multi-step exploratory study from a service & systems perspective focused on the key role of technology
Creators: name: Perillo, Claudia
Publisher: name: Universita degli studi di Salerno
Year: 2023
Subjects: subject: SECS-P/08 ECONOMIA E GESTIONE DELLE IMPRESE
subject: Community care
subject: Service & Systems
subject: Technology

description: 2021 - 2022
description: In our fast-changing world, management and marketing acquire a strategic relevance. They become an important reference and support when it comes to making healthcare more effective, efficient, and sustainable. A key contribution in achieving these goals is played by a systems governance and management of healthcare (Pollard, 2016); hence, by the adoption of a systems approach (Golinelli, 2000, 2010; Barile 2000, 2009). Due to an ageing population and the growing number of patients with comorbidity, the number of patients with chronical illnesses (for which there may not be a cure) is growing. This situation highlights the need to define governance policies capable of ensuring the sustainable development of the economic and social system through appropriate forms of organization. In this problematic context, a need to understand and interpret the complexity of service systems and social phenomena using general schemes of interpretation, arises. Essentially, the complex goal is to balance the effectiveness, efficiency and sustainability of service in the governance of the healthcare system (Saviano, Bassano, & Calabrese, 2010). Accordingly, this study aims to investigate the evolutionary trend of change that the Italian Healthcare System is facing now in order to make healthcare service more effective, efficient and sustainable using the lens of systems thinking as a valid interpretative support of complex phenomena. On the basis of this premise and considering the widely agreed need of increasing community care, especially experienced during the COVID-19 pandemic, more specifically, this work aims to investigate the conditions of the effectiveness, efficiency, sustainability, and also safety, of healthcare services while shifting from the hospital setting to community and home care. This shift is rich of implications and, although hospital care is in actual fact the highest level of assistance in both structural and organizational terms, it may result much more complex to effectively, efficiently and sustainably organize care at a community and home care, given the need of integrating many diverse systems components. .. [edited by Author]
Supplementary document for Piezoelectric-based optical modulator for miniaturized wireless medical implants - 6115939.pdf
Creators: name: Edmunds, Jordan
name: Sonmezoglu, Soner
name: Maharbiz, Michel
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Supplement 1
Spin fluctuations in quantum dots
Creators: name: Sharafutdinov, A. U.
name: Lyubshin, D. S.
name: Burmistrov, I. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We explore the static longitudinal and dynamic transverse spin susceptibilities in quantum dots and nanoparticles within the framework of the Hamiltonian that extends the universal Hamiltonian to the case of uniaxial anisotropic exchange. For the limiting cases of Ising and Heisenberg exchange interactions we ascertain how fluctuations of single-particle levels affect the Stoner instability in quantum dots. We reduce the problem to the statistics of extrema of a certain Gaussian process. We prove that, in spite possible strong randomness of the single-particle levels, the spin susceptibility and all its moments diverge simultaneously at the point which is determined by the standard criterion of the Stoner instability involving the mean level spacing only.
description: 23 pages, 8 figures
Land Management Plan for Fort Sam Houston, Texas
Creators: name: Williams, Ted D.
Publisher: name: Department of the Army
Year: 1972
Subjects: subject: JBSA-Sam Houston
valueUri: https://core.tdar.org/browse/geographic-keyword/82532/jbsa-sam-houston
subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Environmental
valueUri: https://core.tdar.org/browse/other-keyword/76447/environmental
subject: Land Management
valueUri: https://core.tdar.org/browse/other-keyword/33969/land-management
subject: Assessment
valueUri: https://core.tdar.org/browse/other-keyword/30760/assessment
subject: Environment Research
valueUri: https://core.tdar.org/browse/investigation-type/13/environment-research
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: The purpose of this plan is to provide an overall guide for the management and maintenance of lands for which the installation is responsible. This plan is to facilitate the military mission of the installation through the conservation, improvement, and maintenance of its natural resources in accordance with sound agronomic principles. The maintenance of improved and intensively improved grounds, such as lawns, drill fields, open areas, athletic fields, and landscape plantings will be emphasized. This plan is intended for use in conjunction with the Department of the Army Technical Manual 5-630.
Integrated genomic characterization of endometrial carcinoma
Creators: name: Fulton, Lucinda
name: Gabriel, Stacey B.
name: Mardis, Elaine R.
name: Kalicki-Veizer, Joelle
name: Dooling, David
name: Carlsen, Rebecca
name: Schmidt, Heather
name: Ally, Adrian
name: Chu, Andy
name: Chuah, Eric
name: Chun, Hye-Jung E.
name: Balasundaram, Miruna
name: Dhalla, Noreen
name: Sougnez, Carrie
name: McLellan, Michael D.
name: Kandoth, Cyriac
name: O’Laughlin, Michelle
name: Sivachenko, Andrey
name: Hirst, Carrie
name: Fulton, Robert
name: Birol, Inanc
name: Lander, Eric
name: Cibulskis, Kristian
name: Butterfield, Yaron S. N.
name: Holt, Robert A.
name: Ding, Li
name: Lawrence, Mike
name: Carter, Candace
name: Ye, Kai
name: Wilson, Richard K.
name: Guin, Ranabir
name: Getz, Gad
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: SummaryWe performed an integrated genomic, transcriptomic, and proteomic characterization of 373 endometrial carcinomas using array- and sequencing-based technologies. Uterine serous tumors and ~25% of high-grade endometrioid tumors have extensive copy number alterations, few DNA methylation changes, low ER/PR levels, and frequent TP53 mutations. Most endometrioid tumors have few copy number alterations or TP53 mutations but frequent mutations in PTEN, CTNNB1, PIK3CA, ARID1A, KRAS and novel mutations in the SWI/SNF gene ARID5B. A subset of endometrioid tumors we identified had a dramatically increased transversion mutation frequency, and newly identified hotspot mutations in POLE. Our results classified endometrial cancers into four categories: POLE ultramutated, microsatellite instability hypermutated, copy number low, and copy number high. Uterine serous carcinomas share genomic features with ovarian serous and basal-like breast carcinomas. We demonstrated that the genomic features of endometrial carcinomas permit a reclassification that may impact post-surgical adjuvant treatment for women with aggressive tumors.
Constant mean curvature surfaces with boundary on a sphere
Creators: name: López, Rafael
name: Pyo, Juncheol
Publisher: name: arXiv
Year: 2014
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: In this article we study the shape of a compact surface of constant mean curvature of Euclidean space whose boundary is contained in a round sphere. We consider the case that the boundary is prescribed or that the surface meets the sphere with a constant angle. We study under what geometric conditions the surface must be spherical. Our results apply in many scenarios in physics where in absence of gravity a liquid drop is deposited on a round solid ball and the air-liquid interface is a critical point for area under all variations that preserve the enclosed volume.
The larva of Eusynthemis ursula Theischinger (Odonata: Synthemistidae)
Creators: name: Theischinger, G
name: Hawking, J. H
Publisher: name: La Trobe
Year: 2023

description: La Trobe University Faculty of Science, Technology and Engineering Murray Darling Freshwater Research Centre

MDFRC item.

The larva of Eusynthemis Ursula THEISCHINGER is described, illustrated, diagnosed and discussed.
Supplementary document for Piezoelectric-based optical modulator for miniaturized wireless medical implants- 6124510.pdf
Creators: name: Edmunds, Jordan
name: Sonmezoglu, Soner
name: Maharbiz, Michel
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Supplement 1
HIRMEOS. Ein EU-Projekt für Open-Access-Monografien in den Geistes- und Sozialwissenschaften
Creators: name: Bargheer, Margo
name: Bertino, Andrea
Publisher: name: Humboldt-Universität zu Berlin
Year: 2018
Subjects: subject: Monografien
subject: Open Access
subject: digitale Plattformen
subject: Geisteswissenschaften
subject: Sozialwissenschaften
subject: Monographs
subject: digital platforms
subject: humanities
subject: social sciences
subject: 020 Bibliotheks- und Informationswissenschaften

description: Die Sonderstellung der Monografie im Spektrum des wissenschaftlichen Publizierens stellt den Aufbau von Open-Access-Publikationsmodellen in den Geistes- und Sozialwissenschaften (im englischen HSS) vor besondere Herausforderungen. Der Artikel stellt dar, wie das EU-Projekt HIRMEOS (High Integration of Research Monographs in the European Open Science infrastructure) diese Herausforderungen anpackt. Vorgestellt werden Ziele, Partner, Arbeitspakete und Arbeitsmethoden des Projekts sowie die wichtigsten technischen Spezifikationen der implementierten Dienste und Werkzeuge für digitale Monografien.
description: The peculiar position of the monograph in the range of scholarly publishing presents specific challenges for the building of Open Access publication structures in the humanities and in the social sciences (HSS). The article shows how the EU project HIRMEOS (High Integration of Research Monographs in the European Open Science infrastructure) meets these challenges. Objectives, partners, work packages and working methods of the project, as well as the most important technical specifications of the implemented services and tools for digital monographs are presented here.
OAHP Inventory, Camp Bullis, Texas
Creators: name: Tompkins, Sally Kress
Publisher: name: Office of Archaeology and Historic Preservation
Year: 1980
Subjects: subject: Fort Sam Houston
valueUri: https://core.tdar.org/browse/geographic-keyword/83681/fort-sam-houston
subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: OAHP
valueUri: https://core.tdar.org/browse/other-keyword/138292/oahp
subject: Camp Bullis
valueUri: https://core.tdar.org/browse/other-keyword/42859/camp-bullis
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: An inventory form by the Office of Archaeology and Historic Preservation for Camp Bullis, Fort Sam Houston, Texas.
Quantum arithmetic and numerical analysis using Repeat-Until-Success circuits
Creators: name: Wiebe, Nathan
name: Roetteler, Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Numerical Analysis (math.NA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We develop a method for approximate synthesis of single--qubit rotations of the form $e^{-i f(ϕ_1,\ldots,ϕ_k)X}$ that is based on the Repeat-Until-Success (RUS) framework for quantum circuit synthesis. We demonstrate how smooth computable functions $f$ can be synthesized from two basic primitives. This synthesis approach constitutes a manifestly quantum form of arithmetic that differs greatly from the approaches commonly used in quantum algorithms. The key advantage of our approach is that it requires far fewer qubits than existing approaches: as a case in point, we show that using as few as $3$ ancilla qubits, one can obtain RUS circuits for approximate multiplication and reciprocals. We also analyze the costs of performing multiplication and inversion on a quantum computer using conventional approaches and find that they can require too many qubits to execute on a small quantum computer, unlike our approach.
Supplementary document for High-Q electro-optic modulator for miniaturized wireless medical implants - 6051976.pdf
Creators: name: Edmunds, Jordan
name: Sonmezoglu, Soner
name: Maharbiz, Michel
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: supplement 1
Disenfranchised Victims of the Opioid Epidemic: Predicting Grief and Growth after an Opioid-Related Loss
Creators: name: Hill, Erin McKendry
Publisher: name: Digital Repository at the University of Maryland
Year: 2022
Subjects: subject: Counseling psychology
subject: Psychology
subject: FOS: Psychology
subject: Bereavement
subject: Coping
subject: Grief
subject: Opioid-related death
subject: Post-traumatic Growth
subject: Prolonged Grief

description: Over 75,000 people died from opioid drug overdoses between April of 2020 to April of 2021, compared to 46,000 deaths in 2018 (CDC, 2021; Wilson et al., 2020). Left behind are family members, significant others and friends struggling with grief as opioid-related losses are highly stigmatized and disenfranchised. Theoretically informed by the model of resilience (Mancini & Bonanno, 2009), as well as the transactional model of stress, appraisal and coping (Lazarus & Folkman, 1984), this study examined the role of disenfranchised grief, social support, and coping in prolonged grief and posttraumatic growth among a sample (n = 159) of people bereaved by the loss of a family member, romantic partner or friend due to an opioid-related death. Together, disenfranchised grief, social support, and coping predicted 43% of the variance in prolonged grief and 36.6% of the variance in posttraumatic growth. Specifically active emotional coping predicted unique variance in both outcomes. Findings from this study have important implications for research and clinical practice to improve grief outcomes for this unique yet extensive population.
Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1
Creators: name: Feng, Suhua
name: Hale, Christopher J.
name: Patel, Dinshaw J.
name: Krajewski, Krzysztof
name: Jacobsen, Steven E.
name: Du, Jiamu
name: Palanca, Ana Marie S.
name: Law, Julie A.
name: Strahl, Brian D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: DNA methylation is an epigenetic modification that plays critical roles in gene silencing, development, and genome integrity. In Arabidopsis, DNA methylation is established by DOMAINS REARRANGED METHYLTRANSFERASE 2 (DRM2) and targeted by 24 nt small interfering RNAs (siRNAs) through a pathway termed RNA-directed DNA methylation (RdDM)1. This pathway requires two plant-specific RNA polymerases: Pol-IV, which functions to initiate siRNA biogenesis and Pol-V, which functions to generate scaffold transcripts that recruit downstream RdDM factors1,2. To understand the mechanisms controlling Pol-IV targeting we investigated the function of SAWADEE HOMEODOMAIN HOMOLOG 1 (SHH1)3,4, a Pol-IV interacting protein3. Here we show that SHH1 acts upstream in the RdDM pathway to enable siRNA production from a large subset of the most active RdDM targets and that SHH1 is required for Pol-IV occupancy at these same loci. We also show that the SHH1 SAWADEE domain is a novel chromatin binding module that adopts a unique tandem Tudor-like fold and functions as a dual lysine reader, probing for both unmethylated K4 and methylated K9 modifications on the histone 3 (H3) tail. Finally, we show that key residues within both lysine binding pockets of SHH1 are required in vivo to maintain siRNA and DNA methylation levels as well as Pol-IV occupancy at RdDM targets, demonstrating a central role for methylated H3K9 binding in SHH1 function and providing the first insights into the mechanism of Pol-IV targeting. Given the parallels between methylation systems in plants and mammals1,5, a further understanding of this early targeting step may aid in our ability to control the expression of endogenous and newly introduced genes, which has broad implications for agriculture and gene therapy.
Additional file 1 of A multicenter, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of camostat mesilate in patients with COVID-19 (CANDLE study)
Creators: name: Kinoshita, Taku
name: Shinoda, Masahiro
name: Nishizaki, Yasuhiro
name: Shiraki, Katsuya
name: Hirai, Yuji
name: Kichikawa, Yoshiko
name: Tsushima, Kenji
name: Sinkai, Masaharu
name: Komura, Naoyuki
name: Yoshida, Kazuo
name: Kido, Yasutoshi
name: Kakeya, Hiroshi
name: Uemura, Naoto
name: Kadota, Junichi
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1: Study protocol.
Aturus Kramer 1875
Creators: name: Smit, Harry
name: Pešić, Vladimir
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Aturidae
Aturus

description: Genus Aturus Kramer, 1875
A widespread genus, known from all continents except Australia and Antarctica.
description: Published as part of Smit, Harry & Pešić, Vladimir, 2014, Water mites from Mount Kinabalu and the Crocker Range, Borneo, Malaysia (Acari: Hydrachnidia), with the description of 34 new species, pp. 1-71 in Zootaxa 3876 (1) on page 64, DOI: 10.11646/zootaxa.3876.1.1, http://zenodo.org/record/287281
The Complexity of Primes in Computable UFDs
Creators: name: Dzhafarov, Damir D.
name: Mileti, Joseph R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Logic (math.LO)
subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics

description: In many simple integral domains, such as $\mathbb{Z}$ or $\mathbb{Z}[i]$, there is a straightforward procedure to determine if an element is prime by simply reducing to a direct check of finitely many potential divisors. Despite the fact that such a naive approach does not immediately translate to integral domains like $\mathbb{Z}[x]$ or the ring of integers in an algebraic number field, there still exist computational procedures that work to determine the prime elements in these cases. In contrast, we will show how to computably extend $\mathbb{Z}$ in such a way that we can control the ordinary integer primes in any $Π_2^0$ way, all while maintaining unique factorization. As a corollary, we establish the existence of a computable UFD such that the set of primes is $Π_2^0$-complete in every computable presentation.
Optimal Nonparametric Testing of Qualitative Hypotheses
Creators: name: Dümbgen, Lutz
name: Spokoiny, Vladimir
Publisher: name: Weierstrass Institute
Year: 1998
Subjects: subject: adaptivity
subject: convexity
subject: Lévy´s modulus of continuity
subject: monotonicity
subject: positivity
subject: 62G10

description: Suppose one observes a process Y on the unit interval, where dY = ƒ + n-1/2dW with an unknown function parameter ƒ, given scale parameter n ≥ 1 ("sample size") and standard Brownian motion W. We propose two classes of tests of qualitative nonparametric hypotheses about ƒ such as monotonicity or convexity. These tests are asymptotically optimal and adaptive with respect to two different criteria. As a by-product we obtain an extension of Lévy´s modulus of continuity of Brownian motion. It is of independent interest because of its potential applications to simultaneous confidence intervals in nonparametric curve estimation.
Response from Stan Graves to Richard Strimel, Clean Out and Stabilization of Building 614 Shell and Building 654 Demolition, Fort Sam Houston, Texas
Creators: name: Graves, Stanley O.
Publisher: name: Texas Historical Commission
Year: 1990
Subjects: subject: JBSA-Sam Houston
valueUri: https://core.tdar.org/browse/geographic-keyword/82532/jbsa-sam-houston
subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Building 654
valueUri: https://core.tdar.org/browse/other-keyword/146440/building-654
subject: Building 614
valueUri: https://core.tdar.org/browse/other-keyword/146409/building-614
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: This letter contains requests by the Texas Historical Commission for the proposed project of the cleaning and stabilizing of Building 614 shell and the demolition of Building 654.
Supplementary document for High-performance one-dimensional MOSFET array photodetectors in 0.8-μm standard CMOS process - 6056371.pdf
Creators: name: Liu, Yaxuan
name: Sun, Jingye
name: tong, ling
name: Li, Yuning
name: Deng, Tao
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: supplementary materials
Structure of the human smoothened receptor bound to an antitumour agent
Creators: name: Liu, Wei
name: Katritch, Vsevolod
name: Roth, Bryan L.
name: Wang, Chong
name: Stevens, Raymond C.
name: Siu, Fai Yiu
name: Huang, Xi-Ping
name: Cherezov, Vadim
name: Han, Gye Won
name: Wu, Huixian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The smoothened (SMO) receptor, a key signal transducer in the Hedgehog (Hh) signaling pathway is both responsible for the maintenance of normal embryonic development and implicated in carcinogenesis. The SMO receptor is classified as a class Frizzled (class F) G protein-coupled receptor (GPCR), although the canonical Hh signaling pathway involves the transcription factor Gli and the sequence similarity with class A GPCRs is less than 10%. Here we report the crystal structure at 2.5 Å resolution of the transmembrane domain of the human SMO receptor bound to the small molecule antagonist LY2940680. Although the SMO receptor shares the seven transmembrane helical (7TM) fold, most conserved motifs for class A GPCRs are absent, and the structure reveals an unusually complex arrangement of long extracellular loops stabilized by four disulfide bonds. The ligand binds at the extracellular end of the 7TM bundle and forms extensive contacts with the loops.
Topoisomerases facilitate transcription of long genes linked to autism
Creators: name: Zylka, Mark J.
name: Yandava, Chandri N.
name: Mabb, Angela M.
name: Philpot, Benjamin D.
name: King, Ian F.
name: Huang, Hsien-Sung
name: Magnuson, Terry
name: Pearson, Brandon L.
name: Calabrese, J. Mauro
name: Parker, Joel S.
name: Starmer, Joshua
name: Hsiao, Jack S.
name: Chamberlain, Stormy J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Topoisomerases are expressed throughout the developing and adult brain and are mutated in some individuals with autism spectrum disorder (ASD). However, how topoisomerases are mechanistically connected to ASD is unknown. Here we found that topotecan, a Topoisomerase 1 (TOP1) inhibitor, dose-dependently reduced the expression of extremely long genes in mouse and human neurons, including nearly all genes >200 kb. Expression of long genes was also reduced following knockdown of Top1 or Top2b in neurons, highlighting that each enzyme was required for full expression of long genes. By mapping RNA polymerase II density genome-wide in neurons, we found that this length-dependent effect on gene expression was due to impaired transcription elongation. Interestingly, many high confidence ASD candidate genes are exceptionally long and were reduced in expression following TOP1 inhibition. Our findings suggest that chemicals and genetic mutations that impair topoisomerases could commonly contribute to ASD and other neurodevelopmental disorders.
A polygenic burden of rare disruptive mutations in schizophrenia
Creators: name: Scolnick, Edward M.
name: Bergen, Sarah E.
name: McCarroll, Steven A.
name: Lander, Eric S.
name: Gabriel, Stacey
name: Genovese, Giulio
name: Solovieff, Nadia
name: Fromer, Menachem
name: Moran, Jennifer L.
name: Sullivan, Patrick F.
name: Collins, Mark O.
name: Magnusson, Patrik K. E.
name: Fernández, Esperanza
name: Sklar, Pamela
name: Haggarty, Stephen J.
name: Chambert, Kimberly
name: Hultman, Christina M.
name: Garimella, Kiran
name: Roussos, Panos
name: Duncan, Laramie
name: Banks, Eric
name: Choudhary, Jyoti S.
name: O’Dushlaine, Colm
name: Komiyama, Noboru H.
name: Fennell, Tim
name: Purcell, Shaun M.
name: DePristo, Mark
name: Ruderfer, Douglas
name: Shakir, Khalid
name: Grant, Seth G. N.
name: Kähler, Anna
name: Stahl, Eli
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: By analyzing the exome sequences of 2,536 schizophrenia cases and 2,543 controls, we have demonstrated a polygenic burden primarily arising from rare (<1/10,000), disruptive mutations distributed across many genes. Especially enriched genesets included the voltage-gated calcium ion channel and the signaling complex formed by the activity-regulated cytoskeleton-associated (ARC) scaffold protein of the postsynaptic density (PSD), sets previously implicated by genome-wide association studies (GWAS) and copy-number variation (CNV) studies. Similar to reports in autism, targets of the fragile × mental retardation protein (FMRP, product of FMR1) were enriched for case mutations. No individual gene-based test achieved significance after correction for multiple testing and we did not detect any alleles of moderately low frequency (~0.5-1%) and moderately large effect. Taken together, these data suggest that population-based exome sequencing can discover risk alleles and complements established gene mapping paradigms in neuropsychiatric disease.
Supplementary document for High-performance one-dimensional MOSFET array photodetectors in 0.8-μm standard CMOS process - 6111329.pdf
Creators: name: Liu, Yaxuan
name: Sun, Jingye
name: tong, ling
name: Li, Yuning
name: Deng, Tao
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: supplementary materials
An atlas of active enhancers across human cell types and tissues
Creators: name: Boyd, Mette
name: Lilje, Berit
name: Glatz, Dagmar
name: Arner, Erik
name: Bertin, Nicolas
name: Rapin, Nicolas
name: Mungall, Christopher J.
name: Rackham, Owen
name: Andersson, Robin
name: Miguel-Escalada, Irene
name: Bagger, Frederik Otzen
name: Furuhata, Erina
name: Chen, Yun
name: Gebhard, Claudia
name: Li, Kang
name: Raithel, Johanna
name: Ishizu, Yuri
name: Maeda, Shiori
name: Hoof, Ilka
name: Schmidl, Christian
name: Bornholdt, Jette
name: Andersen, Peter Refsing
name: Shimizu, Yuri
name: Schwarzfischer, Lucia
name: Jørgensen, Mette
name: Baillie, J. Kenneth
name: Negishi, Yutaka
name: Zhao, Xiaobei
name: Suzuki, Takahiro
name: Valen, Eivind
name: Ntini, Evgenia
name: Burroughs, A. Maxwell
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Enhancers control the correct temporal and cell type-specific activation of gene expression in higher eukaryotes. Knowing their properties, regulatory activity and targets is crucial to understand the regulation of differentiation and homeostasis. We use the FANTOM5 panel of samples covering the majority of human tissues and cell types to produce an atlas of active, in vivo transcribed enhancers. We show that enhancers share properties with CpG-poor mRNA promoters but produce bidirectional, exosome-sensitive, relatively short unspliced RNAs, the generation of which is strongly related to enhancer activity. The atlas is used to compare regulatory programs between different cells at unprecedented depth, identify disease-associated regulatory single nucleotide polymorphisms, and classify cell type-specific and ubiquitous enhancers. We further explore the utility of enhancer redundancy, which explains gene expression strength rather than expression patterns. The online FANTOM5 enhancer atlas represents a unique resource for studies on cell type-specific enhancers and gene regulation.
Letter from Stan Graves to Donald Peterson, Building 675 Rehabilitation of A Wing, Randolph Air Force Base, Texas
Creators: name: Graves, Stanley O.
Publisher: name: Texas Historical Commission
Year: 1992
Subjects: subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Randolph Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/78971/randolph-air-force-base
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/318/governmental-structure
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Non-Domestic Structures
valueUri: https://core.tdar.org/browse/site-type/309/non-domestic-structures
subject: A Wing
valueUri: https://core.tdar.org/browse/other-keyword/158942/a-wing
subject: Building 675
valueUri: https://core.tdar.org/browse/other-keyword/146456/building-675
subject: Wing A
valueUri: https://core.tdar.org/browse/other-keyword/158939/wing-a
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: The Texas Historical Commission has written this letter to notify Randolph Air Force Base that the proposed removal of casement windows is an Adverse Effect on Building 675. This letter is part of a group of correspondence and documentation regarding the proposed rehabilitation of Building 675 "A" Wing at Randolph Air Force Base, a property eligible for listing on the National Register of Historic Places. Attachments to these letters include location maps, historic data, undertaking description, and photographs.
Additional file 2 of A multicenter, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of camostat mesilate in patients with COVID-19 (CANDLE study)
Creators: name: Kinoshita, Taku
name: Shinoda, Masahiro
name: Nishizaki, Yasuhiro
name: Shiraki, Katsuya
name: Hirai, Yuji
name: Kichikawa, Yoshiko
name: Tsushima, Kenji
name: Sinkai, Masaharu
name: Komura, Naoyuki
name: Yoshida, Kazuo
name: Kido, Yasutoshi
name: Kakeya, Hiroshi
name: Uemura, Naoto
name: Kadota, Junichi
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: Computational Biology

description: Additional file 2: IRB information. Sample size calculation. Table S1. Discontinuation criteria. Table S2. Ordinal scale of severity. Table S3. Events and reasons for censoring patients for the analysis of time to SARS-CoV-2 negativity. Table S4. Events and reasons for censoring patients in the sensitivity analysis of the time to SARS-CoV-2 negativity. Table S5. Changes to the statistical analyses plan from the protocol. Table S6. Patient disposition. Table S7. Results of the sensitivity analysis of the primary endpoint. Table S8. Time to negative SARS-CoV-2 status as measured by the central laboratory. Table S9. Results of the subgroup analyses of time to negative SARS-CoV-2 status.
Hysteresis operators in phase-field models of Penrose-Fife type
Creators: name: Krejčí, Pavel
name: Sprekels, Jürgen
Publisher: name: Weierstrass Institute
Year: 1998
Subjects: subject: Phase-field systems
subject: phase transitions
subject: hysteresis operators
subject: well-posedness of parabolic systems
subject: thermodynamic consistency
subject: Penrose-Fife model
subject: 35K55
subject: 80A22
subject: 47H30

description: Phase-field systems as mathematical models for phase transitions have drawn a considerable interest in recent years. However, while they are capable of capturing many of the experimentally observed phenomena, they are only of restricted value in modelling hysteresis effects occuring during phase transition processes. To overcome this shortcoming of existing phase-field theories, the authors recently proposed a new approach to phase-field models which is based on the mathematical theory of hysteresis operators developed in the past fifteen years. Well-posedness and thermodynamic consistency were proved for a phase-field system with hysteresis which is closely related to the model advanced by Caginalp in a series of papers. In this note the more difficult case of a phase-field system of Penrose-Fife type with hysteresis is investigated. Under slightly more restrictive assumptions than in the Caginalp case it is shown that the system is well-posed and thermodynamically consistent.
Antimatter and antistars in the universe and in the Galaxy
Creators: name: Blinnikov, S. I.
name: Dolgov, A. D.
name: Postnov, K. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider consequences of hypothetical existence of baryo-dense stars created in the very early universe within an extension of Affleck-Dine scenario of baryogenesis. New constraints on the possible number of compact antimatter objects are derived. The contemporary observational data do not exclude significant amount of antimatter in the Galaxy (and in other galaxies) in the form of the baryo-dense low-massive stars.
description: 10 pages
Construction of Mixed-Format Tests in Mathematics Online Testing on Fractions for Grade 6 Students: an Application of One-Parameter Item Response Theory
Creators: name: Kanokporn Jansiharat
Publisher: name: DR.KEN Institute of Academic Development and Promotion
Year: 2023
Subjects: Mixed-format Tests
Online Testing
x Online Testing
Item Response Theory

description: Interdisciplinary Academic and Research Journal, 3, 3, 725-738
Ontology and Quantum Mechanics
Creators: name: Dass, N. D. Hari
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The issue of ontology in quantum mechanics, or equivalently the issue of the reality of the wave function is critically examined within standard quantum theory. It is argued that though no strict ontology is possible within quantum theory, ingenious measurement schemes may still make the notion of a \emph{FAPP Ontology} i.e ontology for all practical purposes (a phrase coined by John Bell), meaningful and useful.
description: 19 pages in LaTeX
Additional file 3 of A multicenter, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of camostat mesilate in patients with COVID-19 (CANDLE study)
Creators: name: Kinoshita, Taku
name: Shinoda, Masahiro
name: Nishizaki, Yasuhiro
name: Shiraki, Katsuya
name: Hirai, Yuji
name: Kichikawa, Yoshiko
name: Tsushima, Kenji
name: Sinkai, Masaharu
name: Komura, Naoyuki
name: Yoshida, Kazuo
name: Kido, Yasutoshi
name: Kakeya, Hiroshi
name: Uemura, Naoto
name: Kadota, Junichi
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: Computational Biology

description: Additional file 3: CONSORT Checklist.
Some analytical properties of the multidimensional continuous Mróz model of plasticity
Creators: name: Brokate, Martin
name: Krejčí, Pavel
name: Rachinskii, Dmitrii
Publisher: name: Weierstrass Institute
Year: 1998
Subjects: subject: Kinematic hardening
subject: Mróz model
subject: constitutive operator
subject: memory
subject: equations with hysteresis
subject: 47H30
subject: 73E05
subject: 47H15

description: We study the geometrical structure of memory induced by the continuous multidimensional Mróz model of plasticity. The results are used for proving the thermodynamic consistency of the model and composition and inversion formulas for input - memory state - output operators. We also show an example of nonuniqueness of solutions to a simple initial value problem involving the Mróz operator.
Fluxograma: Mucormicose (Fungo Negro)
Creators: name: Da Costa Xavier, Ana Beatriz
name: De Moura Lira, Ana Vitória
name: Assis, Caroline Nascimento
name: De Andrade, Delízia Pinheiro
name: Da Rosa Ventura, Desirê
name: Da Silva Gama, Maria Eduarda
name: Da Silva, Millena Albuquerque
Publisher: name: Zenodo
Year: 2023
Subjects: Micologia
Mucormicose
Fungo Negro

description: Fluxograma sobre Mucormicose (Fungo Negro), elaborado como instrumento de avaliação, produzido pelas Graduandas de Enfermagem da Escola De Enfermagem Aurora de Afonso Costa - Universidade Federal Fluminense.
The response of macroinvertebrates to inundation in floodplain wetlands: a possible effect of river regulation?
Creators: name: Quinn, G. P
name: Hillman, T. J
name: Cook, R
Publisher: name: La Trobe
Year: 2023

description: La Trobe University Faculty of Science, Technology and Engineering Murray Darling Freshwater Research Centre

MDFRC item.

A large number of permanent and temporary wetlands are associated with the lowland rivers in south-eastern Australia. Regulation of these rivers for irrigated agriculture has probably increased the temporary nature of some wetlands because the reduced frequency of overbank flows causes them to remain dry for longer. The responses of macroinvertebrate assemblages(species composition and abundance) to inundation in permanent and temporary wetlands on the floodplain of the unregulated Ovens River were examined, and these responses were compared with those from permanent and temporary wetlands in the Barmah-Millewa forest of the regulated River Murray. The compositions of macroinvertebrate assemblages in permanent wetlands could not be distinguished from those of temporary wetlands on the Ovens after inundation, although changes in abundance of some taxa (especially chironomids) meant that the assemblages in permanent wetlands differed significantly before and after flooding. In contrast, after inundation permanent and temporary wetlands in the Barmah-Millewa forest differed significantly and this difference was sustained through time. This different response of macroinvertebrate assemblages on the two floodplains may be an effect of regulation, although other explanations, such as differences between the floodplains in the mechanism of inundation and historical water regimes, or climatic differences between years, may also be important. Further studies should include concurrent sampling on a wider range of regulated floodplains and experiments manipulating water allocations to wetlands, to test specific hypotheses about the effects of water regime on biota.
Autonomous models on a Cayley tree
Creators: name: Khorrami, Mohammad
name: Aghamohammadi, Amir
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The most general single species autonomous reaction-diffusion model on a Cayley tree with nearest-neighbor interactions is introduced. The stationary solutions of such models, as well as their dynamics, are discussed. To study dynamics of the system, directionally-symmetric Green function for evolution equation of average number density is obtained. In some limiting cases the Green function is studied. Some examples are worked out in more detail.
description: 12 pages
Commoners: Cooperation, Fairness, and Resource Management in Changing Tzotzil-Maya Communities, Southern Mexico
Creators: name: Hertzog, Werner
Publisher: name: Zenodo
Year: 2020
Subjects: anthropology
commons
cognition
maya
mexico
economic anthropology
cognitive anthropology
tzotzil
modernization
native americans
behavioral games

description: This study focuses on social change, resource management, cooperation, and fairness among Tzotzil-Maya communities in the highlands of Chiapas, southern Mexico. Maya groups in Chiapas have undergone drastic changes over the past five decades. While modernization has upended some of their traditional dependence on agriculture, Maya political systems have become more decentralized, with communities now managing resources autonomously. Other recent transformations include increasing market integration, greater access to urban centers, the expansion of formal schooling, and the advent of state-sponsored social change. This dissertation investigates the effects of this multifaceted process of change on local resource management by comparing rural and urban Tzotzil communities that differ in degree of access to markets and modern infrastructure. The study uses a mixed-methods approach combining: (1) ethnographic methods to document the processes through which communities and households make resource allocation decisions; and (2) economic and behavioral experiments to index moral preferences in how people solve hypothetical problems of resource allocation. Each chapter delves into a different factor shaping how Tzotzil communities cooperate and manage resources. These topics include ethnicity, fairness and equity norms, kinship and land tenure systems, and labor allocation. I find that modernization causes resource allocation to shift from a prestige-based to a need-based logic. I assert that this change reflects the evolving social structure of Tzotzil groups. As modernization undermines traditional prestige hierarchies, novel notions of fairness and equity emerge in response to new resource conflict configurations. The research shows how cognition, moral values, and social structure can be interlinked and reinforce each other in a context of ongoing social change. These findings can inform environmental and social policy in the developing world by shedding light on how modernization processes taking place rural settings affect local resource management. The study proposes new methods for researching the relationship between culture, cognition, and the environment.
Response from Demetrio Jimenez to Emmitt Smith, Building 526, Randolph Air Force Base, Texas
Creators: name: Jimenez, Demetrio
Publisher: name: Texas Historical Commission
Year: 1993
Subjects: subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Randolph Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/78971/randolph-air-force-base
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/318/governmental-structure
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Building 526
valueUri: https://core.tdar.org/browse/other-keyword/153013/building-526
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: After touring Building 526 and reviewing the summary information on the proposed undertakings at Randolph Air Force Base, the Texas Historical Commission proposes that rather than demolishing the historic structure, it should be used as a storage facility as long as it is usable. This letter is part of a packet of correspondence concerning the proposed demolition of Building 526, Randolph Air Force Base, Texas. Attachments include engineering reports, description, and location map.
Sharp bounds on perfect retrieval in the Hopfield model
Creators: name: Bovier, Anton
Publisher: name: Weierstrass Institute
Year: 1998
Subjects: subject: Hopfield model
subject: storage capacity
subject: gradient dynamic
subject: sequential dynamic
subject: 82B44
subject: 60K35
subject: 82C32

description: We prove a sharp upper bound on the number of patterns that can be stored in the Hopfield model if the stored patterns are required to be fixed points of the gradient dynamic. We also show corresponding bounds on the one-step convergence of the sequential gradient dynamic. The bounds coincide with the known lower bounds and confirm the heuristic expectations. The proof is based on a crucial idea of Loukianova [L] to use the negative association properties of some random variables arising in the analysis.
Magnetic form factor analysis on detwinned single crystal of BaFe$_2$As$_2$
Creators: name: Kodama, K.
name: Ishikado, M.
name: Wakimoto, S.
name: Kohou, K.
name: Lee, C. H.
name: Iyo, A.
name: Eisaki, H.
name: Shamoto, S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We have performed neutron diffraction measurement on a single crystal of parent compound of iron-based superconductor, BaFe$_2$As$_2$ at 12~K. In order to investigate in-plane anisotropy of magnetic form factor in the antiferromagnetic phase, the detwinned single crystal is used in the measurement. The magnetic structure factor and magnetic form factor are well explained by the spin densities consisting of $3d_{yz}$ electrons with a fraction of about 40~\% and the electrons in the other four $3d$ orbitals with each fraction of about 15~\%. Such anisotropic magnetic form factor is qualitatively consistent with the anisotropic magnetic behaviors observed in the antiferromagnetic phase of the parent compound of iron-based superconductor.
description: 5 pages, 4 figures