cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Antioxidant Therapies for Ulcerative Dermatitis: A Potential Model for Skin Picking Disorder
Creators: name: Garner, Joseph P.
name: Vieira, Giovana
name: Fletcher, Craig A.
name: Whitaker, Julia
name: Bellinger, Dwight A.
name: George, Nneka M.
name: Geronimo, Jerome T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Skin Picking Disorder affects 4% of the general population, with serious quality of life impacts, and potentially life threatening complications. Standard psychoactive medications do not help most patients. Similarly, Mouse Ulcerative Dermatitis (skin lesions caused by excessive abnormal grooming behavior) is very common in widely used inbred strains of mice, and represents a serious animal welfare issue and cause of mortality. Treatment options for Ulcerative Dermatitis are largely palliative and ineffective. We have proposed mouse Ulcerative Dermatitis as a model for human Skin Picking Disorder based on similar epidemiology, behavior, and its comorbidity and mechanistic overlap with hair pulling (trichotillomania). We predicted that mouse Ulcerative Dermatitis would be treated by N-Acetylcysteine, as this compound is highly effective in treating both Skin Picking Disorder and Trichotillomania. Furthermore, we hypothesized that N-Acetylcysteine’s mode of action is as a precursor to the production of the endogenous antioxidant glutathione in the brain, and therefore intranasal glutathione would also treat Ulcerative Dermatitis. Accordingly, we show in a heterogenous prospective trial, the significant reduction in Ulcerative Dermatitis lesion severity in mice receiving either N-acetylcysteine (oral administration) or glutathione (intranasal). The majority of mice treated with N-acetylcysteine improved slowly throughout the course of the study. Roughly half of the mice treated with glutathione showed complete resolution of lesion within 2-4 weeks, while the remainder did not respond. These findings are the first to show that the use of N-acetylcysteine and Glutathione can be curative for mouse Ulcerative Dermatitis. These findings lend additional support for mouse Ulcerative Dermatitis as a model of Skin Picking Disorder and also support oxidative stress and glutathione synthesis as the mechanism of action for these compounds. As N-Acetylcysteine is poorly tolerated by many patients, intranasal glutathione warrants further study as potential therapy in Skin Picking, trichotillomania and other body-focused repetitive behavior disorders.
Spectroscopic Pulsational Frequency and Mode Determination of the $γ$ Doradus Star HD 189631
Creators: name: Davie, Matthew W.
name: Pollard, Karen R.
name: Cottrell, Peter L.
name: Brunsden, Emily
name: Wright, Duncan J.
name: De Cat, Peter
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present improvement and confirmation of identified frequencies and pulsation modes for the $γ$ Doradus star HD 189631. This work improves upon previous studies by incorporating a significant number of additional spectra and precise determination of frequencies. Four frequencies were identified for this star: $1.6774 \pm 0.0002$ d$^{-1}$, $1.4174 \pm 0.0002$ d$^{-1}$, $0.0714 \pm 0.0002$ d$^{-1}$, and $1.8228 \pm 0.0002$ d$^{-1}$ which were identified with the modes ($l$,$m$) = ($1,+1$), ($1,+1$), ($2,-2$), and ($1,+1$) respectively. These findings are in agreement with the most recent literature. The prevalence of ($l$,$m$) = ($1,+1$) modes in $γ$ Doradus stars is starting to become apparent and we discuss this result.
description: Accepted in PASA, 7 Apr 2014
Specializations of partial differential equations for Feynman integrals
Creators: name: Bytev, Vladimir V.
name: Kniehl, Bernd A.
name: Veretin, Oleg
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2022
Subjects: subject: 530
subject: differential equations
subject: Feynman graph
subject: propagator
subject: master integral

description: Starting from the Mellin–Barnes integral representation of a Feynman integral depending on a set of kinematic variables zi, we derive a system of partial differential equations w.r.t. new variables xj, which parameterize the differentiable constraints zi=yi(xj). In our algorithm, the powers of propagators can be considered as arbitrary parameters. Our algorithm can also be used for the reduction of multiple hypergeometric sums to sums of lower dimension, finding special values and reduction equations of hypergeometric functions in a singular locus of continuous variables, or finding systems of partial differential equations for master integrals with arbitrary powers of propagators. As an illustration, we produce a differential equation of fourth order in one variable for the one-loop two-point Feynman diagram with two different masses and arbitrary propagator powers.
Efficient Design of Reversible Sequential Circuit
Creators: name: Mamun, Md. Selim Al
name: Mandal, Indrani
name: Hasanuzzaman, Md.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Emerging Technologies (cs.ET)
subject: FOS: Computer and information sciences

description: Reversible logic has come to the forefront of theoretical and applied research today. Although many researchers are investigating techniques to synthesize reversible combinational logic, there is little work in the area of sequential reversible logic. Latches and flip-flops are the most significant memory elements for the forthcoming sequential memory elements. In this paper, we proposed two new reversible logic gates MG-1 and MG-2. We then proposed new design techniques for latches and flip-flops with the help of the new proposed gates. The proposed designs are better than the existing ones in terms of number of gates, garbage outputs and delay.
description: IOSR Journal of Computer Engineering (IOSR-JCE) 5.6(2012)
Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers
Creators: name: Petit, Anna
name: Lester, Jenny
name: Wang, Xianshu
name: Cajal, Teresa Ramón y
name: Nevanlinna, Heli
name: Cuadras, Daniel
name: Karlan, Beth Y.
name: Walsh, Christine
name: Català, Isabel
name: Berenguer, Antoni
name: Mai, Phuong L.
name: Greene, Mark H.
name: Arun, Banu K.
name: de Garibay, Gorka Ruiz
name: Bonifaci, Núria
name: Tornero, Eva
name: Benítez, Javier
name: Osorio, Ana
name: Rozas, Julio
name: McGuffog, Lesley
name: Feliubadaló, Lidia
name: Kuchenbaecker, Karoline
name: Librado, Pablo
name: Pankratz, Vernon S.
name: Brunet, Joan
name: Mateo, Francesca
name: Sánchez-Gracia, Alejandro
name: Islam, Abul
name: Barrowdale, Daniel
name: Aittomäki, Kristiina
name: Toland, Amanda E.
name: Blanco, Ignacio
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: While interplay between BRCA1 and AURKA-RHAMM-TPX2-TUBG1 regulates mammary epithelial polarization, common genetic variation in HMMR (gene product RHAMM) may be associated with risk of breast cancer in BRCA1 mutation carriers. Following on these observations, we further assessed the link between the AURKA-HMMR-TPX2-TUBG1 functional module and risk of breast cancer in BRCA1 or BRCA2 mutation carriers. Forty-one single nucleotide polymorphisms (SNPs) were genotyped in 15,252 BRCA1 and 8,211 BRCA2 mutation carriers and subsequently analyzed using a retrospective likelihood approach. The association of HMMR rs299290 with breast cancer risk in BRCA1 mutation carriers was confirmed: per-allele hazard ratio (HR) = 1.10, 95% confidence interval (CI) 1.04 – 1.15, p = 1.9 x 10−4 (false discovery rate (FDR)-adjusted p = 0.043). Variation in CSTF1, located next to AURKA, was also found to be associated with breast cancer risk in BRCA2 mutation carriers: rs2426618 per-allele HR = 1.10, 95% CI 1.03 – 1.16, p = 0.005 (FDR-adjusted p = 0.045). Assessment of pairwise interactions provided suggestions (FDR-adjusted pinteraction values > 0.05) for deviations from the multiplicative model for rs299290 and CSTF1 rs6064391, and rs299290 and TUBG1 rs11649877 in both BRCA1 and BRCA2 mutation carriers. Following these suggestions, the expression of HMMR and AURKA or TUBG1 in sporadic breast tumors was found to potentially interact, influencing patients’ survival. Together, the results of this study support the hypothesis of a causative link between altered function of AURKA-HMMR-TPX2-TUBG1 and breast carcinogenesis in BRCA1/2 mutation carriers.
Seasonality in the Brazilian Pantanal influences avian functional diversity
Creators: name: de Deus, Filipe Ferreira
name: Schuchmann, Karl-L.
name: Marques, Marinêz Isaac
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 60506 Virology

description: Seasonality significantly affects environmental changes in the Pantanal, especially during wet and dry periods. Inundation and drought impact the onset of flowering and fruiting and the occurrence of insects. Because such resources may vary across seasons, it is expected that avian functional diversity also changes. We examine how functional diversity changed over time, as measured by functional richness and functional divergence. For functional richness, we observed a functionally overdispersed bird community over the seasons, whereas for functional divergence, two different patterns were found: (1) functionally overdispersed bird communities during the wet and receding seasons and (2) functionally clustered avian communities in the dry and rising seasons. The diversity of functional groups did not significantly vary across the seasons, as expected, but varied between forests and savannas. The environment has restricted resources in certain seasons, benefiting species with specific functional characteristics, however, bird species in the Pantanal are often generalists adapted to using a wide variety of food resources. Although the habitat turnover rate is an important factor that influences bird species composition across seasons, the changes in species composition still allowed the maintenance of certain functional characteristics, contributing to conservation of the existing functional groups in the ecosystem.
PID4NFDI - A Base4NFDI Service to Enhanced Research Data  Management
Creators: name: Genderjahn, Steffi
name: Kahlert, Torsten
Publisher: name: Zenodo
Year: 2024
Subjects: PIDs
NFDI
BASE4NFDI
Metadata
FAIR

description: The PID4NFDI project is an initiative aimed at enhancing the use and management of Persistent Identifiers (PIDs) within the framework of the National Research Data Infrastructure (NFDI) in Germany. The poster provides an overview of the importance of PIDs and how PID4NFDI aims to address the needs of the community.
Isometry-invariant geodesics and the fundamental group
Creators: name: Mazzucchelli, Marco
Publisher: name: arXiv
Year: 2014
Subjects: subject: Differential Geometry (math.DG)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 58E10, 53C22

description: We prove that on closed Riemannian manifolds with infinite abelian, but not cyclic, fundamental group, any isometry that is homotopic to the identity possesses infinitely many invariant geodesics. We conjecture that the result remains true if the fundamental group is infinite cyclic. We also formulate a generalization of the isometry-invariant geodesics problem, and a generalization of the celebrated Weinstein conjecture: on a closed contact manifold with a selected contact form, any strict contactomorphism that is contact-isotopic to the identity possesses an invariant Reeb orbit.
description: 14 pages
On Joint Source-Channel Coding for Correlated Sources Over Multiple-Access Relay Channels
Creators: name: Murin, Yonathan
name: Dabora, Ron
name: Gündüz, Deniz
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We study the transmission of correlated sources over discrete memoryless (DM) multiple-access-relay channels (MARCs), in which both the relay and the destination have access to side information arbitrarily correlated with the sources. As the optimal transmission scheme is an open problem, in this work we propose a new joint source-channel coding scheme based on a novel combination of the correlation preserving mapping (CPM) technique with Slepian-Wolf (SW) source coding, and obtain the corresponding sufficient conditions. The proposed coding scheme is based on the decode-and-forward strategy, and utilizes CPM for encoding information simultaneously to the relay and the destination, whereas the cooperation information from the relay is encoded via SW source coding. It is shown that there are cases in which the new scheme strictly outperforms the schemes available in the literature. This is the first instance of a source-channel code that uses CPM for encoding information to two different nodes (relay and destination). In addition to sufficient conditions, we present three different sets of single-letter necessary conditions for reliable transmission of correlated sources over DM MARCs. The newly derived conditions are shown to be at least as tight as the previously known necessary conditions.
description: Accepted to TIT
Association between Plasma 25-Hydroxyvitamin D, Ancestry and Aggressive Prostate Cancer among African Americans and European Americans in PCaP
Creators: name: Woloszynska-Read, Anna
name: Trump, Donald L.
name: Zhang, Hongmei
name: Arab, Lenore
name: Su, Joseph L.
name: Bensen, Jeannette T.
name: Smith, Gary J.
name: Johnson, Candace S.
name: Mohler, James L.
name: Fontham, Elizabeth T. H.
name: Steck, Susan E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: African Americans (AAs) have lower circulating 25-hydroxyvitamin D3 [25(OH)D3] concentrations and higher prostate cancer (CaP) aggressiveness than other racial/ethnic groups. The purpose of the current study was to examine the relationship between plasma 25(OH)D3, African ancestry and CaP aggressiveness among AAs and European Americans (EAs).
Mountains and traits: environmental heterogeneity and mammal assemblages along an elevational gradient in the Northern Andes
Creators: name: Mena, José L.
name: Pacheco, Víctor
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Plant Biology

description: We assessed the variation of both composition and functional diversity of mammals along an elevation gradient (1600–3600 masl) at the Tabaconas Namballe National Sanctuary (TNNS) in northern Peru. Using a camera-trap design (85 stations, 8,825 camera days, ~ 317 km2), we recorded a total of 33 mammalian species during the dry season of 2016. Species-specific effects of environmental covariates based on multi-species occupancy modeling showed that only elevation had a statistically significant effect on occupancy. Also, a principal coordinate analysis and a distance-based redundancy analysis suggested that the variation in species composition is mainly explained by elevation, and moderately by both the normalized difference vegetation index (NDVI) and the distance to roads. The highlands appear to be dominated by a reduced assembly of species consisting of the montane guinea pig, the Andean fox, and the northern pudu. Functional diversity decreased with elevation, providing evidence that lowland and highland communities are functionally dissimilar. Moreover, land-use is changing rapidly in the areas surrounding the TNNS, suggesting that increased connectivity at the two extremes of the elevational gradient (the highlands and the lowlands) will ensure the long-term viability of terrestrial mammalian populations and, thus, the ecological processes in which they are involved.
Scotogenic Inverse Seesaw Model of Neutrino Mass
Creators: name: Fraser, Sean
name: Ma, Ernest
name: Popov, Oleg
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A variation of the original 2006 radiative seesaw model of neutrino mass through dark matter is shown to realize the notion of inverse seesaw naturally. The dark-matter candidate here is the lightest of three real singlet scalars which may also carry flavor.
description: 10 pages, 2 figures, version to appear in PLB
Association of White Blood Cell Count and Differential with the Incidence of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study
Creators: name: Norby, Faye L.
name: Agarwal, Sunil K.
name: Loehr, Laura R.
name: Bekwelem, Wobo
name: Alonso, Alvaro
name: Soliman, Elsayed Z.
name: Misialek, Jeffrey R.
name: Chen, Lin Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Although inflammation is involved in the development of atrial fibrillation (AF), the association of white blood cell (WBC) count and differential with AF has not been thoroughly examined in large cohorts with extended follow-up.
Floral visiting bees of Humiria balsamifera var. floribunda (Humiriaceae) and its pollen transport network, in a restinga environment
Creators: name: Pinto, Rafael Sousa
name: Silva, Albeane Guimarães
name: de Albuquerque, Patrícia Maia Correia
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Cell Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: The flowers of Humiria balsamifera var. floribunda were monitored for 1 year in an area of restinga on the Brazilian coast to describe the richness of visiting bees, temporal distribution of visits, and how they transport its pollen in the community. The plant showed continuous flowering and bees were seen foraging nectar throughout the year. A total of 1,231 individuals belonging to 17 bee species were collected. The highest frequencies belonged to social species (Melipona subnitida, Apis mellifera, Melipona fasciculata) and Xylocopa cearensis. In general, bee visits were positively correlated to increased flowering intensity of the plant. The most frequent species increased their visitation frequency throughout the day, which may be related to optimal foraging decisions. Twenty-two pollen types were identified on the bee bodies. Social bees presented the highest loads of monofloral H. balsamifera pollen, which contributed to greater cross pollination success of this plant. The network structure was nested, which demonstrates the plant’s potential to stabilize the pollination system. Thus, as a generalist plant, H. balsamifera helps maintain bees in the restinga, which is currently an environment severely threatened by anthropic actions.
Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis
Creators: name: Gibson, Kevin F.
name: Xue, Jianmin
name: Duncan, Steven R.
name: Chien, Nydia
name: Donahoe, Michael
name: Valentine, Vincent G.
name: Saul, Melissa
name: Raval, Jay S.
name: Zhang, Yingze
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: BackgroundSevere acute exacerbations (AE) of idiopathic pulmonary fibrosis (IPF) are medically untreatable and often fatal within days. Recent evidence suggests autoantibodies may be involved in IPF progression. Autoantibody-mediated lung diseases are typically refractory to glucocorticoids and nonspecific medications, but frequently respond to focused autoantibody reduction treatments. We conducted a pilot trial to test the hypothesis that autoantibody-targeted therapies may also benefit AE-IPF patients.MethodsEleven (11) critically-ill AE-IPF patients with no evidence of conventional autoimmune diseases were treated with therapeutic plasma exchanges (TPE) and rituximab, supplemented in later cases with intravenous immunoglobulin (IVIG). Plasma anti-epithelial (HEp-2) autoantibodies and matrix metalloproteinase-7 (MMP7) were evaluated by indirect immunofluorescence and ELISA, respectively. Outcomes among the trial subjects were compared to those of 20 historical control AE-IPF patients treated with conventional glucocorticoid therapy prior to this experimental trial.ResultsNine (9) trial subjects (82%) had improvements of pulmonary gas exchange after treatment, compared to one (5%) historical control. Two of the three trial subjects who relapsed after only five TPE responded again with additional TPE. The three latest subjects who responded to an augmented regimen of nine TPE plus rituximab plus IVIG have had sustained responses without relapses after 96-to-237 days. Anti-HEp-2 autoantibodies were present in trial subjects prior to therapy, and were reduced by TPE among those who responded to treatment. Conversely, plasma MMP7 levels were not systematically affected by therapy nor correlated with clinical responses. One-year survival of trial subjects was 46+15% vs. 0% among historical controls. No serious adverse events were attributable to the experimental medications.ConclusionThis pilot trial indicates specific treatments that reduce autoantibodies might benefit some severely-ill AE-IPF patients. These findings have potential implications regarding mechanisms of IPF progression, and justify considerations for incremental trials of autoantibody-targeted therapies in AE-IPF patients.Trial RegistrationClinicalTrials.gov NCT01266317
Adsorption of acetic acid on ion exchange resin in aqueous and non-aqueous conditions: batch equilibrium study and thermodynamic analysis
Creators: name: Khedkar, Manisha A.
name: Nimbalkar, Pranhita R.
name: Bankar, Sandip B.
name: Chavan, Prakash V.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology

description: Adsorptive removal of acetic acid from aqueous and non-aqueous solutions was carried out using strong base anion exchange resin at 303, 313, and 323 K. The effect of concentration of acetic acid, nature of solvent, and temperature on adsorption of acetic acid and swelling of the resin were investigated. Adsorption of acetic acid and swelling of the resin were favoured in non-polar solvents for a given temperature. Adsorption of acetic acid was favoured at 303 K and decreased with an increase in temperature. Langmuir isotherm model was fitted to equilibrium adsorption data to determine the Langmuir adsorption constant and saturation capacity of the resin. Further, thermodynamic parameters viz. ΔGO, ΔHO, and ΔSO were estimated. The negative values of ΔGO and ΔHO showed that the adsorption of acetic acid on the resin was spontaneous and exothermic in nature.
Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores
Creators: name: Doyle, Sean P.
name: Abdullah, Lubna H.
name: Lethem, Michael I.
name: Davis, C. William
name: Vasquez, Paula A.
name: Nguyen, Kristine
name: Ribeiro, Carla M. P.
name: Zhu, Yunxiang
name: Forest, M. Gregory
name: Dickey, Burton F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Airway mucin secretion studies have focused on goblet cell responses to exogenous agonists almost to the exclusion of baseline mucin secretion (BLMS). In human bronchial epithelial cell cultures (HBECCs), maximal agonist-stimulated secretion exceeds baseline by ~3-fold as measured over hour-long periods, but mucin stores are discharged completely and require 24 h for full restoration. Hence, over 24 h, total baseline exceeds agonist-induced secretion by several-fold. Studies with HBECCs and mouse tracheas showed that BLMS is highly sensitive to mechanical stresses. Harvesting three consecutive 1 h baseline luminal incubations with HBECCs yielded equal rates of BLMS; however, lengthening the middle period to 72 h decreased the respective rate significantly, suggesting a stimulation of BLMS by the gentle washes of HBECC luminal surfaces. BLMS declined exponentially after washing HBECCs (t1/2 = 2.75 h), to rates approaching zero. HBECCs exposed to low perfusion rates exhibited spike-like increases in BLMS when flow was jumped 5-fold: BLMS increased >4 fold, then decreased within 5 min to a stable plateau at 1.5–2-fold over control. Higher flow jumps induced proportionally higher BLMS increases. Inducing mucous hyperplasia in HBECCs increased mucin production, BLMS and agonist-induced secretion. Mouse tracheal BLMS was ~6-fold higher during perfusion, than when flow was stopped. Munc13-2 null mouse tracheas, with their defect of accumulated cellular mucins, exhibited similar BLMS as WT, contrary to predictions of lower values. Graded mucous metaplasia induced in WT and Munc13-2 null tracheas with IL-13, caused proportional increases in BLMS, suggesting that naïve Munc13-2 mouse BLMS is elevated by increased mucin stores. We conclude that BLMS is, [i] a major component of mucin secretion in the lung, [ii] sustained by the mechanical activity of a dynamic lung, [iii] proportional to levels of mucin stores, and [iv] regulated differentially from agonist-induced mucin secretion.
Exact ground state for the four-electron problem in a 2D finite honeycomb lattice
Creators: name: Trencsenyi, Reka
name: Glukhov, Konstantin
name: Gulacsi, Zsolt
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Working in a subspace with dimensionality much smaller than the dimension of the full Hilbert space, we deduce exact 4-particle ground states in 2D samples containing hexagonal repeat units and described by Hubbard type of models. The procedure identifies first a small subspace ${\cal{S}}$ in which the ground state $|Ψ_g\rangle$ is placed, than deduces $|Ψ_g\rangle$ by exact diagonalization in ${\cal{S}}$. The small subspace is obtained by the repeated application of the Hamiltonian $\hat H$ on a carefully chosen starting wave vector describing the most interacting particle configuration, and the wave vectors resulting from the application of $\hat H$, till the obtained system of equations closes in itself. The procedure which can be applied in principle at fixed but arbitrary system size and number of particles, is interesting by its own since provides exact information for the numerical approximation techniques which use a similar strategy, but apply non-complete basis for ${\cal{S}}$. The diagonalization inside ${\cal{S}}$ provides an incomplete image about the low lying part of the excitation spectrum, but provides the exact $|Ψ_g\rangle$. Once the exact ground state is obtained, its properties can be easily analyzed. The $|Ψ_g\rangle$ is found always as a singlet state whose energy, interestingly, saturates in the $U \to \infty$ limit. The unapproximated results show that the emergence probabilities of different particle configurations in the ground state present "Zittern" (trembling) characteristics which are absent in 2D square Hubbard systems. Consequently, the manifestation of the local Coulomb repulsion in 2D square and honeycomb types of systems presents differences, which can be a real source in the differences in the many-body behavior.
description: 35 pages, 21 figures
Levels of genetic differentiation and gene flow between four populations of the Scaly-naped Pigeon, Patagioenas squamosa: implications for conservation
Creators: name: Cambrone, Christopher
name: Cézilly, Frank
name: Wattier, Rémi
name: Eraud, Cyril
name: Bezault, Etienne
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Island-endemic columbid species are particularly vulnerable to environmental degradation, extreme climatic events, and interactions with exotic species. The situation might be even more critical in the case of exploited species, where legal hunting and poaching can severely affect population dynamics. Here we document for the first time the genetic structure of the Scaly-naped Pigeon, Patagioenas squamosa, a Caribbean-endemic columbid species of cynegetic interest, over a large part of its range. Using both mitochondrial DNA and nuclear markers (microsatellites), we investigated gene flow, genetic diversity, and genetic structure among four islands populations originating from Puerto-Rico, Guadeloupe, Martinique and Barbados. We found evidence for a significant genetic differentiation only between the Barbados and the three other populations, consistent with the fact that the Barbados population originated from a few captive individuals escaped from a rooftop aviary in Bridgetown about 100 years ago. Given the absence of genetic differentiation between Puerto Rico and the French Antilles, our results suggest that, apart from Barbados, the species may mainly consist of a single large, homogeneous population. We discuss the relevance of our findings in relation to management and conservation issues.
BMPER Promotes Epithelial-Mesenchymal Transition in the Developing Cardiac Cushions
Creators: name: Dyer, Laura
name: Patterson, Cam
name: Lockyer, Pamela
name: Moser, Martin
name: Wu, Yaxu
name: Cyr, Chelsea
name: Saha, Arnab
name: Pi, Xinchun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Formation of the cardiac valves is an essential component of cardiovascular development. Consistent with the role of the bone morphogenetic protein (BMP) signaling pathway in cardiac valve formation, embryos that are deficient for the BMP regulator BMPER (BMP-binding endothelial regulator) display the cardiac valve anomaly mitral valve prolapse. However, how BMPER deficiency leads to this defect is unknown. Based on its expression pattern in the developing cardiac cushions, we hypothesized that BMPER regulates BMP2-mediated signaling, leading to fine-tuned epithelial-mesenchymal transition (EMT) and extracellular matrix deposition. In the BMPER-/- embryo, EMT is dysregulated in the atrioventricular and outflow tract cushions compared with their wild-type counterparts, as indicated by a significant increase of Sox9-positive cells during cushion formation. However, proliferation is not impaired in the developing BMPER-/- valves. In vitro data show that BMPER directly binds BMP2. In cultured endothelial cells, BMPER blocks BMP2-induced Smad activation in a dose-dependent manner. In addition, BMP2 increases the Sox9 protein level, and this increase is inhibited by co-treatment with BMPER. Consistently, in the BMPER-/- embryos, semi-quantitative analysis of Smad activation shows that the canonical BMP pathway is significantly more active in the atrioventricular cushions during EMT. These results indicate that BMPER negatively regulates BMP-induced Smad and Sox9 activity during valve development. Together, these results identify BMPER as a regulator of BMP2-induced cardiac valve development and will contribute to our understanding of valvular defects.
Physical, mechanical, and electrical properties of rice starch-based films plasticised by ionic liquid
Creators: name: Roy, Joydev
name: Bhattacharya, Suvendu
name: Sahu, Partha Pratim
name: Das, Amit Baran
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A biodegradable film was developed using an ionic liquid as a plasticiser, and rice starch having medium amylose content. The physical, mechanical and electrical properties of the developed films were determined and analysed employing the principles of chemometrics. The water vapour transmission and elongation of the films increased with 1-butyl-3-methylimidazolium chloride (BMIMCl) concentration. The highest melting temperature was 133.4°C when the concentration of BMIMCl was 4% (w/w). The crystallinity and extent of modification were characterised by XRD and FTIR. The highest conduction of film was 0.29 S/m while the lowest resistance observed was 3.42 Ωm. The chemometric analysis of parameters of the film was carried out in terms of hierarchical cluster analysis (HCA) and principal component analysis (PCA). This study demonstrated the possibility of using rice starch with BMIMCl as the plasticiser to design an electroconductive film having the desired heating characteristics.
Sign Reversal of anisotropic magnetoresistance in La0.7Ca0.3MnO3/STO ultrathin films
Creators: name: Sharma, Himanshu
name: Tulapurkar, A.
name: Tomy, C. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present the observation of strain induced sign reversal of anisotropic magnetoresistance (AMR) in LCMO (LCMO) ultrathin films (thickness 4 nm) deposited on STO (001) substrate (STO). We have also observed unusually large AMR in LCMO/STO thin films with thickness of 6 nm below but close to its Curie temperature (TC) which decrease as the film thickness increases. The sign reversal of AMR (with a maximum value of - 6) with magnetic field or temperature for the 4 nm thin film may be attributed to the increase in tensile strain in the plane of the thin film which in turn facilitates the rotation of the magnetization easy axis.
Reclamation of tungsten from spent HDS catalyst: a detailed study
Creators: name: Mahalik, Surjeet
name: Sheik, A. R.
name: Dash, Barsha
name: Sarangi, C. K.
name: Sanjay, K.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Science Policy

description: The awareness of the depletion of high grade ore is of paramount importance now-a-days for all the metallurgical industries and researchers. For the conservation of resources, processing of low and lean grade ores is very much essential. Moreover, the recycling and reuse of the secondaries must be the core strength in that context. The spent catalyst obtained from a petroleum refinery was having 20.33% WO3 and 49.14% Al2O3 as major part of the matrix. The spent catalyst was devolatilized at 650°C to remove the oils, organics and other volatile matter. The devolatilized spent catalyst was processed treated with 8% NaOH at 90°C for 3 h to dissolve tungsten as sodium tungstate. The W bearing liquor was treated with H2SO4 to precipitate tungstic acid at pH 1.0. and subsequent production of tungsten trioxide by roasting at 700°C and tungsten metal with 99.91% purity by reduction roasting by H2 gas has also been reported. The alkali leached residue was leached with 10% sulphuric acid at 80°C for 2 h so as to extract nickel and later on precipitated as nickel hydroxide.
Descriptions of new species of hymenopterous insects collected by Mr. A. R. Wallace at Celebes. (Part Formicidae)
Creators: name: Smith, F.
Publisher: name: Zenodo
Year: 1860
Subjects: Biodiversity
Taxonomy

description: 1. Pseudomyrma læviceps, Smith, Proc. Linn. Soc. 1859, iii. p. 145. Hab. Celebes; Aru. The specimens from Makassar are smaller than those from Aru, but I can detect no specific difference.
description: Published as part of Smith, F., 1860, Descriptions of new species of hymenopterous insects collected by Mr. A. R. Wallace at Celebes. (Part Formicidae), pp. 57-93 in Journal of the Proceedings of the Linnean Society of London, Zoology 5 on page 72
M Times Photon Subtraction-Addition Coherent Superposition Operated Odd-Schrődinger-cat State: Nonclassicality and Decoherence
Creators: name: Huang, Li
name: Guo, Qin
name: Jiang, Li-ying
name: Chen, Ge
name: Xu, Xue-xiang
name: Yuan, Wen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We introduce a new non-Gaussian state, generated by m times coherent superposition operation $a\cos θ+a^{\dagger }e^{iφ}\sin θ$ (MCSO) on odd-Schrodinger-cat state (OSCS). Its normalized constant is turned out to be related with the Hermite polynomial. We further investigate the nonclassical properties of the MCSO-OSCS through Mandel's Q-parameter, quadrature squeezing, the photocount distribution and Wigner function (WF). It is shown that the nonclassicality of the MCSO-OSCS is influenced by the number of times (m) of coherent superpositon operation, the angle $θ$ and the amplitude of the coherent state (|$α_{0}$|). Especially the volume of negative region of WF increases with the increment of parameters m, $θ$ and $α_{0}$. We also investigate the decoherence of the MCSO-OSCS in terms of the fadeaway of the negativity of WF in a thermal environment.
description: 14 pages with 10 figures
Can Genetic Analysis of Putative Blood Alzheimer’s Disease Biomarkers Lead to Identification of Susceptibility Loci?
Creators: name: Koenig, Jessica L.
name: Barber, Robert C.
name: Tilson, Jeffrey L.
name: Wilhelmsen, Kirk C.
name: Waring, Stephen C.
name: Chasse, Scott
name: O’Bryant, Sid E.
name: Huebinger, Ryan M.
name: Shewale, Shantanu J.
name: Phillips, Nicole R.
name: Diaz-Arrastia, Ramon
name: Mitchel, Jeffrey S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Although 24 Alzheimer’s disease (AD) risk loci have been reliably identified, a large portion of the predicted heritability for AD remains unexplained. It is expected that additional loci of small effect will be identified with an increased sample size. However, the cost of a significant increase in Case-Control sample size is prohibitive. The current study tests whether exploring the genetic basis of endophenotypes, in this case based on putative blood biomarkers for AD, can accelerate the identification of susceptibility loci using modest sample sizes. Each endophenotype was used as the outcome variable in an independent GWAS. Endophenotypes were based on circulating concentrations of proteins that contributed significantly to a published blood-based predictive algorithm for AD. Endophenotypes included Monocyte Chemoattractant Protein 1 (MCP1), Vascular Cell Adhesion Molecule 1 (VCAM1), Pancreatic Polypeptide (PP), Beta2 Microglobulin (B2M), Factor VII (F7), Adiponectin (ADN) and Tenascin C (TN-C). Across the seven endophenotypes, 47 SNPs were associated with outcome with a p-value ≤1x10-7. Each signal was further characterized with respect to known genetic loci associated with AD. Signals for several endophenotypes were observed in the vicinity of CR1, MS4A6A/MS4A4E, PICALM, CLU, and PTK2B. The strongest signal was observed in association with Factor VII levels and was located within the F7 gene. Additional signals were observed in MAP3K13, ZNF320, ATP9B and TREM1. Conditional regression analyses suggested that the SNPs contributed to variation in protein concentration independent of AD status. The identification of two putatively novel AD loci (in the Factor VII and ATP9B genes), which have not been located in previous studies despite massive sample sizes, highlights the benefits of an endophenotypic approach for resolving the genetic basis for complex diseases. The coincidence of several of the endophenotypic signals with known AD loci may point to novel genetic interactions and should be further investigated.
Beyond the Eye: Multisensory Contributions to the Sensation of Illusory Self-Motion (Vection)
Creators: name: E. Riecke, Bernhard
name: Murovec, Brandy
name: L. Campos, Jennifer
name: Keshavarz, Behrang
Publisher: name: Brill Online
Year: 2023
Subjects: classificationCode: 520406
subject: Sensory processes, perception and performance

description: Vection is typically defined as the embodied illusion of self-motion in the absence of real physical movement through space. Vection can occur in real-life situations (e.g., ‘train illusion’) and in virtual environments and simulators. The vast majority of vection research focuses on vection caused by visual stimulation. Even though visually induced vection is arguably the most compelling type of vection, the role of nonvisual sensory inputs, such as auditory, biomechanical, tactile, and vestibular cues, have recently gained more attention. Non-visual cues can play an important role in inducing vection in two ways. First, nonvisual cues can affect the occurrence and strength of vection when added to corresponding visual information. Second, nonvisual cues can also elicit vection in the absence of visual information, for instance when observers are blindfolded or tested in darkness. The present paper provides a narrative review of the literature on multimodal contributions to vection. We will discuss both the theoretical and applied relevance of multisensory processing as related to the experience of vection and provide design considerations on how to enhance vection in various contexts.
Performance Comparison of Linear Prediction based Vocoders in Linux Platform
Creators: name: Mathew, Lani Rachel
name: Anselam, Ancy S.
name: Pillai, Sakuntala S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Multimedia (cs.MM)
subject: Sound (cs.SD)
subject: FOS: Computer and information sciences

description: Linear predictive coders form an important class of speech coders. This paper describes the software level implementation of linear prediction based vocoders, viz. Code Excited Linear Prediction (CELP), Low-Delay CELP (LD-CELP) and Mixed Excitation Linear Prediction (MELP) at bit rates of 4.8 kb/s, 16 kb/s and 2.4 kb/s respectively. The C programs of the vocoders have been compiled and executed in Linux platform. Subjective testing with the help of Mean Opinion Score test has been performed. Waveform analysis has been done using Praat and Adobe Audition software. The results show that MELP and CELP produce comparable quality while the quality of LD-CELP coder is much higher, at the expense of higher bit rate.
description: 5 pages, 5 figures, Published with International Journal of Engineering Trends and Technology (IJETT)
Recognizing Good Governance in District Procurement
Creators: name: Bukuluki, Paul
name: Brigham Daniels
name: Buntaine, Mark
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Public Affairs, Public Policy and Public Administration
subject: Political Science
subject: FOS: Political science
subject: Social and Behavioral Sciences
subject: corruption
subject: procurement
subject: transparency

description: This project tests whether eligibility for positive recognition improves procurement practices that are vital for good public management. It is a partnership-based randomized experiment, with implementation led by Transparency International Uganda (TIU). The study specifically investigates whether offering district accounting teams positive recognition for meeting established standards about transparency in procurement boosts the level of adherence to those standards. TIU will recruit 50 district accounting teams to be trained and supported to consistently upload procurement actions onto the national procurement portal, something required by law but currently only seldomly completed. While training and support will be offered to all 50 districts in the experimental sample, 25 will be randomly assigned to a positive recognition treatment. Districts in the treatment group will be notified that if they achieve high performance in meeting the transparency standards, they will receive positive, symbolic recognition as part of a national awards ceremony co-hosted by TIU, Makerere University, and the Public Procurement and Disposal of Public Assets Authority (PPDA). Our main hypothesis is that eligibility for recognition will increase the disclosure of public expenditures and procurement-related documentation on the PPDA’s online Government of Uganda Procurement Portal.
A moving boundary problem for the Stokes equations involving osmosis: variational modelling and short-time well-posedness
Creators: name: Lippoth, Friedrich
name: Peletier, Mark A.
name: Prokert, Georg
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35R37, 35K55, 76M30, 80M30

description: Within the framework of variational modelling we derive a one-phase moving boundary problem describing the motion of a semipermeable membrane enclosing a viscous liquid, driven by osmotic pressure and surface tension of the membrane. For this problem we prove the existence of classical solutions for a short time.
Cavitation Enhancing Nanodroplets Mediate Efficient DNA Fragmentation in a Bench Top Ultrasonic Water Bath
Creators: name: Jayakody, Chatura N.
name: Dayton, Paul A.
name: Pattenden, Samantha G.
name: Malc, Ewa P.
name: Mieczkowski, Piotr A.
name: Janzen, William P.
name: Tsuruta, James K.
name: Kasoji, Sandeep K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: A perfluorocarbon nanodroplet formulation is shown to be an effective cavitation enhancement agent, enabling rapid and consistent fragmentation of genomic DNA in a standard ultrasonic water bath. This nanodroplet-enhanced method produces genomic DNA libraries and next-generation sequencing results indistinguishable from DNA samples fragmented in dedicated commercial acoustic sonication equipment, and with higher throughput. This technique thus enables widespread access to fast bench-top genomic DNA fragmentation.