cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Serotonin-2C and -2a receptor co-expression on cells in the rat medial prefrontal cortex
Creators: name: Sonneborn, A.
name: Roth, B. L.
name: Pehek, E. A.
name: Nocjar, C.
name: Abbas, A. I.
name: Alex, K. D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Neural function within the medial prefrontal cortex (mPFC) regulates normal cognition, attention and impulse control, implicating neuroregulatory abnormalities within this region in mental dysfunction related to schizophrenia, depression and drug abuse. Both serotonin -2A (5-HT2A) and -2C (5-HT2C) receptors are known to be important in neuropsychiatric drug action and are distributed throughout the mPFC. However, their interactive role in serotonergic cortical regulation is poorly understood. While the main signal transduction mechanism for both receptors is stimulation of phosphoinositide production, they can have opposite effects downstream. 5-HT2A versus 5-HT2C receptor activation oppositely regulates behavior and can oppositely affect neurochemical release within the mPFC. These distinct receptor effects could be caused by their differential cellular distribution within the cortex and/or other areas. It is known that both receptors are located on GABAergic and pyramidal cells within the mPFC, but it is not clear whether they are expressed on the same or different cells. The present work employed immunofluorescence with confocal microscopy to examine this in layers V-VI of the prelimbic mPFC. The majority of GABA cells in the deep prelimbic mPFC expressed 5-HT2C receptor immunoreactivity. Furthermore, most cells expressing 5-HT2C receptor immunoreactivity notably co-expressed 5-HT2A receptors. However, 27% of 5-HT2C receptor immunoreactive cells were not GABAergic, indicating that a population of prelimbic pyramidal projection cells could express the 5-HT2C receptor. Indeed, some cells with 5-HT2C and 5-HT2A receptor co-labeling had a pyramidal shape and were expressed in the typical layered fashion of pyramidal cells. This indirectly demonstrates that 5-HT2C and 5-HT2A receptors may be commonly co-expressed on GABAergic cells within the deep layers of the prelimbic mPFC and perhaps co-localized on a small population of local pyramidal projection cells. Thus a complex interplay of cortical 5-HT2A and 5-HT2C receptor mechanisms exists, which if altered, could modulate efferent brain systems implicated in mental illness.
(400142) Jane Smythe Lindsay
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The downward spiral of chronic pain, prescription opioid misuse, and addiction: Cognitive, affective, and neuropsychopharmacologic pathways
Creators: name: Partin, Kaitlyn
name: Howard, Matthew O.
name: Froeliger, Brett
name: Garland, Eric L.
name: Zeidan, Fadel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Prescription opioid misuse and addiction among chronic pain patients are emerging public health concerns of considerable significance. Estimates suggest that more than 10% of chronic pain patients misuse opioid analgesics, and the number of fatalities related to nonmedical or inappropriate use of prescription opioids is climbing. Because the prevalence and adverse consequences of this threat are increasing, there is a pressing need for research that identifies the biobehavioral risk chain linking chronic pain, opioid analgesia, and addictive behaviors. To that end, the current manuscript draws upon current neuropsychopharmacologic research to provide a conceptual framework of the downward spiral leading to prescription opioid misuse and addiction among chronic pain patients receiving opioid analgesic pharmacotherapy. Addictive use of opioids is described as the outcome of a cycle initiated by chronic pain and negative affect and reinforced by opioidergic-dopamingeric interactions, leading to attentional hypervigilance for pain and drug cues, dysfunctional connectivity between self-referential and cognitive control networks in the brain, and allostatic dysregulation of stress and reward circuitry. Implications for clinical practice are discussed; multimodal, mindfulness-oriented treatment is introduced as a potentially effective approach to disrupting the downward spiral and facilitating recovery from chronic pain and opioid addiction.
title: Integrative evaluation of computer assisted learning in geography in schools and university
Creators: name: Al-Fagih, Ahmed H.
Publisher: name: University of Glasgow
Year: 1997
Subjects: subject: Educational technology, geography, computer-assisted instruction.

description: Evaluating CAL as part of an overall teaching and learning situation, can help school and university teachers to recognise strengths and weaknesses in their use and delivery of teaching method. This approach is called "integrative evaluation". This research extends the application of integrative evaluation methods to Computer Assisted Learning (CAL) in three ways: (1) to use the integrative approach at the secondary school level for the first time; (2) to investigate deep vs. surface learning in university students using CAL in conjunction with other resources; (3) to apply integrative evaluation to the field of CAL in Geography teaching for the first time. The research comprises four studies, each dealing with a different CAL package. Two of the studies were conducted in two secondary schools in the city of Glasgow, and two were carried out in the Geography Department at the University of Glasgow. The total sample population was 238 (74 school pupils and 164 university students). Various instruments besides classroom observation were used for evaluation purposes, including tests designed to measure learning outcomes, questionnaires designed to gauge pupils'/students' reactions, opinions and confidence levels and interviews. The software studied in this research comprised: (1) A database-like dealing with the geography of Japan. (2) An interactive CAL package related to the subject of the Weather. (3) A university-level CAL package on the subject of Glaciation which related theory to practical labs. (4) Five different application programs (including GIS and Minitab) being taught to university students in an IT course. In the 3 studies that measured learning, the evaluations showed definite gain due to the CAL, although with interesting variations from objective to objective. Among the other findings of the research are: (1) Two distinct patterns of correlation between CAL gains and pupils' geographical ability were detected in each of the school-based studies. It was concluded that low ability pupils gained more from a stimulating, interactive CAL package, but benefited less than more able pupils from a database-type package. (2) Students found the scheduled computer lab the most useful learning resource for learning about the five applications covered in the IT course. This finding clearly demonstrated that each resource had a specific role to play within the course, and that each resource is more suited to the achievement of certain learning objectives and less suitable for others. (3) Only a small shift from surface to deep learning was found by the end of the Glaciation course, even though the CAL package was specifically designed to link theoretical and practical knowledge. However, doubts raised about the design of questions used to determine the shift suggest that the shift may have been underestimated.
Transport Process in Multi-Junctions of Quantum Systems
Creators: name: Kimura, Taro
name: Murata, Masaki
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider the junction of multiple one-dimensional systems and study how conserved currents transport at the junction. To characterize the transport process, we introduce reflection/transmission coefficients by applying boundary conformal field theory. We compute the reflection/transmission coefficients for some examples to derive the closed formulas. The formulas demonstrate spin-flip transport, where the spin polarization is flipped at the junction.
description: 1+19 pages, 4 figures
(400138) Alison Mackenzie
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Executive Leadership in the 21st Century under the Office of Buriram Primary Education Service Area 2
Creators: name: Thongsut, Anan
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Leadership
Management in the 21st Century
Buri Ram Primary Educational Service Area Office 2

description: Interdisciplinary Academic and Research Journal, 3, 3, 415-428
(400139) Charlotte Hannah Young
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Problems and Guidelines of Student Support System Operation of Schools under the Office of Yasothon Primary Education Service Area 2
Creators: name: Anupan Rattanawan
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Student Support System
Yasothon Primary Educational Service Area Office 2
Operational Problems

description: Interdisciplinary Academic and Research Journal, 3, 3, 429-442
Activity-dependent signaling mechanisms regulating adult hippocampal neural stem cells and their progeny
Creators: name: Song, Juan
name: Crowther, Andrew J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Adult neural stem cells (NSCs) reside in a restricted microenvironment, where their development is controlled by subtle and presently underexplored cues. This raises a significant question: what instructions must be provided by this supporting niche to regulate NSC development and functions? Signaling from the niche is proposed to control many aspects of NSC behavior, including balancing the quiescence and proliferation of NSCs, determining the cell division mode (symmetric versus asymmetric), and preventing premature depletion of stem cells to maintain neurogenesis throughout life. Interactions between neurogenic niches and NSCs also govern the homeostatic regulation of adult neurogenesis under diverse physiological, environmental, and pathological conditions. An important implication from revisiting many previously-identified regulatory factors is that most of them (e.g., the antidepressant fluoxetine and exercise) affect gross neurogenesis by acting downstream of NSCs at the level of intermediate progenitors and neuroblasts, while leaving the NSC pool unaffected. Therefore, it is critically important to address how various niche components, signaling pathways, and environmental stimuli differentially regulate distinct stages of adult neurogenesis.
Trace decategorification of the Hecke category
Creators: name: Elias, Ben
name: Lauda, Aaron D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics

description: We compute the trace decategorification of the Hecke category for an arbitrary Coxeter group. More generally, we introduce the notion of a strictly object-adapted cellular category and calculate the trace for such categories.
description: 13 pages
Prefrontal gray matter increases in healthy individuals after lithium treatment: A voxel-based morphometry study
Creators: name: Nicoletti, Mark A.
name: Brambilla, Paolo
name: Matsuo, Koji
name: Soares, Jair C.
name: Caetano, Sheila
name: Sassi, Roberto B.
name: Hatch, John P.
name: Dalwani, Manish
name: Dierschke, Nicole
name: Mallinger, Allan G.
name: Monkul, E. Serap
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The objective of this study was to test the hypothesis that 4 weeks of lithium administration would be associated with changes in brain gray and white matter volumes in healthy individuals. Thirteen right-handed healthy volunteers (6 females, mean age = 25.9 ± 10.0 y) were studied. 3D SPGR MRIs (TR = 25ms, TE = 5ms, slice-thickness = 1.5mm) were acquired using a 1.5 T GE Signa Imaging System, at baseline and after 4 weeks of lithium administration at therapeutically relevant doses. Optimized voxel based morphometry (VBM) analyses were conducted. Left and right dorsolateral prefrontal cortex and left anterior cingulate gray matter volumes increased significantly following lithium administration. Total white matter volume was increased, whereas total brain volume and total gray matter volume were not significantly changed following 4 weeks of lithium. Lithium treatment resulted in prefrontal regional gray matter volume increases in healthy volunteers, as well as increases in total white matter volume. Whether these changes are mediated by neurotrophic/neuroprotective or osmotic effects remains unknown.
The Teachers' Satisfaction Towards Desirable Characteristics of Administrators under the Special Education Administration Office in Lopburi Province
Creators: name: Apichit Ngernkongkaew
Publisher: name: DR.KEN Institute of Academic Development and Promotion
Year: 2023
Subjects: Desirable Characteristics
Executives of the Office of Special Education Administration

description: Interdisciplinary Academic and Research Journal, 3, 3, 443-454
Placental Hypoxia during Placental Malaria
Creators: name: Meshnick, Steven R.
name: Molyneux, Malcolm E.
name: Boeuf, Philippe
name: Romagosa, Cleofe
name: Mwapasa, Victor
name: Tan, Aimee
name: Radford, Jane
name: Hunt, Nicholas H.
name: Rogerson, Stephen J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Placental malaria causes fetal growth retardation (FGR), which has been linked epidemiologically to placental monocyte infiltrates. We investigated whether parasite or monocyte infiltrates were associated with placental hypoxia, as a potential mechanism underlying malarial FGR.
Participation of Resident Forces, District Protection Suit to Drive Amendments Problems of Unrest in the Narathiwat Province Area
Creators: name: Phiranrat Rungsai
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Participation
Local Force
Resolving Unrest in Narathiwat Province

description: Interdisciplinary Academic and Research Journal, 3, 3, 455-468
(400140) Elizabeth Kate Clay
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Lyapunov-Razumikhin techniques for state-dependent delay differential equations
Creators: name: Humphries, A. R.
name: Magpantay, F. M. G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 34K20, 37L45

description: We present Lyapunov stability and asymptotic stability theorems for steady state solutions of general state-dependent delay differential equations (DDEs) using Lyapunov-Razumikhin methods. Our results apply to DDEs with multiple discrete state-dependent delays, which may be nonautonomous for the Lyapunov stability result, but autonomous (or periodically forced) for the asymptotic stability result. Our main technique is to replace the DDE by a nonautonomous ordinary differential equation (ODE) where the delayed terms become source terms in the ODE. The asymptotic stability result and its proof are entirely new, and based on a contradiction argument together with the Arzela-Ascoli theorem. This approach alleviates the need to construct auxiliary functions to ensure the asymptotic contraction, which is a feature of all other Lyapunov-Razumikhin asymptotic stability results of which we are aware. We apply our results to a state-dependent model equation which includes Hayes equation as a special case, to directly establish asymptotic stability in parts of the stability domain along with lower bounds on the size of the basin of attraction.
An effective architectural criticism teaching framework link and enhance design skills
Creators: name: Desouki, Mahmoud
name: Shiba, Ahmed Salah Eldin
name: Elboshy, Bahaa
Publisher: name: figshare
Year: 2023
Subjects: Architectural design

description: Architectural education needs to incorporate the available means to acquire the necessary skills for the practical field and develop them. Architectural criticism is a significant skill that could help the student to learn the architectural design. Most of architectural criticism courses relay on the theoretical teaching in isolation from the practical application and the architectural design process. This study is concerned with integrating the teaching of architectural criticism with the development of architectural design skills an assess the effect of this in improve the students’ design skills. In this regard, the paper develops an effective framework to teach architectural criticism. The presented framework integrates several strategies such as introducing theoretical background, group discussion, teamwork and competition-based project. The proposed framework has been implemented on the third-year students in the architectural department in Nile higher institute of engineering and technology, Mansoura, Egypt. The conducted experiment reveals that the practicing of criticism in the classroom could increase students’ capabilities in architectural design. The evaluation of the experiment based on students’ assessment questionnaire covering different stages of the framework. Based on this evaluation some amendments have been recommended to improve the framework and formulate the final version of the course framework. The evaluation and discussion of the results could improve a cohesive architectural criticism curriculum and teaching framework.
Antibodies to Variant Surface Antigens of Plasmodium falciparum –Infected Erythrocytes Are Associated with Protection from Treatment Failure and the Development of Anemia in Pregnancy
Creators: name: Simpson, Julie A.
name: Meshnick, Steven R.
name: Rogerson, Stephen J.
name: Kalilani, Linda
name: Aitken, Elizabeth
name: Yosaatmadja, Francisca
name: Feng, Gaoqian
name: Jaworowski, Anthony
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: In pregnancy associated malaria (PAM), Plasmodium falciparum infected erythrocytes (IEs) express variant surface antigens (VSA-PAM) that evade existing immunity and mediate placental sequestration. Antibodies to VSA-PAM develop with gravidity and block placental adhesion or opsonise IEs for phagocytic clearance, protecting women from anemia and low birth weight
(400141) George Clement Boase
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The neuroscience of body memory: Recent findings and conceptual advances
Creators: name: Repetto, Claudia
name: Riva, Giuseppe
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2023
Subjects: body representation
body memory
body matrix
advanced technologies
interoception
bodily illusions

description: The body is a very special object, as it corresponds to the physical component of the self and it is the medium through which we interact with the world. Our body awareness includes the mental representation of the body that happens to be our own, and traditionally has been defined in terms of body schema and body image. Starting from the distinction between these two types of representations, the present paper tries to reconcile the literature around body representations under the common framework of body memory. The body memory develops ontogenetically from birth and across all the life span and is directly linked to the development of the self. Therefore, our sense of self and identity is fundamentally based on multisensory knowledge accumulated in body memory, so that the sensations collected by our body, stored as implicit memory, can unfold in the future, under suitable circumstances. Indeed, these sets of bodily information had been proposed as possible key factors underpinning several mental health illnesses. Following this perspective, the Embodied Medicine approach put forward the use of advanced technologies to alter the dysfunctional body memory to enhance people’s well-being. In the last sections, recent experimental pieces of evidence will be illustrated that targeted specifically bodily information for increasing health and wellbeing, by means of two strategies: interoceptive feedback and bodily illusions.
description: EXCLI Journal; 22:Doc191; ISSN 1611-2156
Microwave Quantum Illumination
Creators: name: Barzanjeh, Shabir
name: Guha, Saikat
name: Weedbrook, Christian
name: Vitali, David
name: Shapiro, Jeffrey H.
name: Pirandola, Stefano
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Quantum illumination is a quantum-optical sensing technique in which an entangled source is exploited to improve the detection of a low-reflectivity object that is immersed in a bright thermal background. Here we describe and analyze a system for applying this technique at microwave frequencies, a more appropriate spectral region for target detection than the optical, due to the naturally-occurring bright thermal background in the microwave regime. We use an electro-optomechanical converter to entangle microwave signal and optical idler fields, with the former being sent to probe the target region and the latter being retained at the source. The microwave radiation collected from the target region is then phase conjugated and upconverted into an optical field that is combined with the retained idler in a joint-detection quantum measurement. The error probability of this microwave quantum-illumination system, or quantum radar, is shown to be superior to that of any classical microwave radar of equal transmitted energy.
description: Main Letter. See arXiv:1410.4008 for an extended version including supplemental material
CYP2B6 Variants and Plasma Efavirenz Concentrations during Antiretroviral Therapy in Port‐au‐Prince, Haiti
Creators: name: Haas, David W.
name: Rezk, Naser L.
name: Leger, Paul
name: Beauharnais, Carole Anne
name: Kashuba, Angela D.M.
name: Pape, Jean William
name: Fitzgerald, Daniel W.
name: Dillingham, Rebecca
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Polymorphisms in CYP2B6 are known to predict increased steady-state plasma concentrations of efavirenz. We characterized relationships between genetic polymorphisms and plasma efavirenz concentrations among 45 Haitians who initiated antiretroviral therapy in Port-au-Prince.
Cardinal Interpolation With General Multiquadrics: Convergence Rates
Creators: name: Hamm, Keaton
name: Ledford, Jeff
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 41A05, 41A25, 41A30, 41A63, 42B15

description: This article pertains to interpolation of Sobolev functions at shrinking lattices $h\mathbb{Z}^d$ from $L_p$ shift-invariant spaces associated with cardinal functions related to general multiquadrics, $ϕ_{α,c}(x):=(|x|^2+c^2)^α$. The relation between the shift-invariant spaces generated by the cardinal functions and those generated by the multiquadrics themselves is considered. Additionally, $L_p$ error estimates in terms of the dilation $h$ are considered for the associated cardinal interpolation scheme. This analysis expands the range of $α$ values which were previously known to give such convergence rates (i.e. $O(h^k)$ for functions with derivatives of order up to $k$ in $L_p$, $1
description: Wholesale changes from previous version; 26 pages, Submitted
(400132) Catherine Mary Boase
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Regimen Simplification to Atazanavir‐Ritonavir Alone as Maintenance Antiretroviral Therapy: Final 48‐Week Clinical and Virologic Outcomes
Creators: name: Mellors, John W.
name: Swindells, Susan
name: Wiegand, Ann
name: Woodward, William
name: Thal, Gary
name: Palmer, Sarah
name: Maldarelli, Frank
name: DiRienzo, A. Gregory
name: Wilkin, Timothy J.
name: Godfrey, Catherine
name: McKinnon, John E.
name: Mollan, Katie
name: Bastow, Barbara
name: Fletcher, Courtney V.
name: Margolis, David M.
name: Coffin, John M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Simplified maintenance therapy with ritonavir-boosted atazanavir (ATV/RTV) alone is attractive because of nucleoside reverse-transcriptase inhibitor (NRTI)–sparing benefits, low pill burden, once-daily dosage, and safety.
(400133) Clement Boase
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Increased Risk of HIV Acquisition among Kenyan Men with Human Papillomavirus Infection
Creators: name: Hudgens, Michael G.
name: Meijer, Chris J.L.M.
name: Maclean, Ian
name: Agot, Kawango
name: Moses, Stephen
name: Bailey, Robert C.
name: Ndinya-Achola, Jeckoniah O.
name: Parker, Corette B.
name: Snijders, Peter J.F.
name: Smith, Jennifer S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Few data are available concerning the effect of human papillomavirus (HPV) infection on HIV acquisition.
Multiple Genetic Backgrounds of the Amplified Plasmodium falciparum Multidrug Resistance ( pfmdr 1) Gene and Selective Sweep of 184F Mutation in Cambodia
Creators: name: Muth, Sinuon
name: Meshnick, Steven R.
name: Udhayakumar, Venkatachalam
name: Wongsrichanalai, Chansuda
name: Rogers, William O.
name: Escalante, Ananias A.
name: Alam, Md Tauqeer
name: Lim, Pharath
name: Vinayak, Sumiti
name: Susanti, Augustina I.
name: Ariey, Frederick
name: Fandeur, Thierry
name: Sem, Rithy
name: Maguire, Jason D.
name: Shah, Naman K.
name: Barnwell, John W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The emergence of artesunate-mefloquine (AS+MQ)–resistant Plasmodium falciparum in the Thailand-Cambodia region is a major concern for malaria control. Studies indicate that copy number increase and key alleles in the pfmdr1 gene are associated with AS+MQ resistance. In the present study, we investigated evidence for a selective sweep around pfmdr1 because of the spread of adaptive mutation and/or multiple copies of this gene in the P. falciparum population in Cambodia.
Nano-modulated electron beams via electron diffraction and emittance exchange for coherent x-ray generation
Creators: name: Nanni, Emilio A.
name: Graves, William S.
name: Moncton, David E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: We present a new method for generation of relativistic electron beams with current modulation on the nanometer scale and below. The current modulation is produced by diffracting relativistic electrons in single crystal Si, accelerating the diffracted beam and imaging the crystal structure, then transferring the image into the temporal dimension via emittance exchange. The modulation period can be tuned by adjusting electron optics after diffraction. This tunable longitudinal modulation can have a period as short as a few angstroms, enabling production of coherent hard x-rays from a source based on inverse Compton scattering with total accelerator length of approximately ten meters. Electron beam simulations from cathode emission through diffraction, acceleration and image formation with variable magnification are presented along with estimates of the coherent x-ray output properties.
Murine Model of Clostridium difficile Infection with Aged Gnotobiotic C57BL/6 Mice and a BI/NAP1 Strain
Creators: name: Kolling, G. L.
name: Guerrant, R. L.
name: Calabrese, G.
name: Liu, B.
name: Alcantara Warren, C.
name: Freire, R.
name: Pawlowski, Sean W.
name: Sartor, R. B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The increased incidence and severity of Clostridium difficile infection (CDI) in older adults (age, ⩾65 years) corresponds with the emergence of the BI/NAP1 strain, making elucidation of the host immune response extremely important. We therefore infected germ-free C57BL/6 mice aged 7–14 months with a BI/NAP1 strain and monitored the mice for response. Infected mice were moribund 48–72 h after infection and developed gross and histological cecitis and colitis and elevated concentrations of keratinocyte chemoattractant, interleukin 1β, monocyte chemotactic protein 1, and granulocyte colony-stimulating factor and decreased levels of interferon γ, interleukin 12 p40, interleukin 12 p70, and interleukin 10 compared with controls. We conclude that aged, germ-free C57BL/6 mice are susceptible to fulminant CDI from a BI/NAP1 strain and represent a novel model to further elucidate the host immune response to acute CDI.
Pre‐existing Minority Drug‐Resistant HIV‐1 Variants, Adherence, and Risk of Antiretroviral Treatment Failure
Creators: name: Meyer III, William A.
name: Gulick, Roy M.
name: Paredes, Roger
name: Lalama, Christina M.
name: Shikuma, Cecilia
name: Kuritzkes, Daniel R.
name: Fiscus, Susan A.
name: Johnson, Victoria A.
name: Ribaudo, Heather J.
name: D'Aquila, Richard T.
name: Schackman, Bruce R.
name: Gigue, Francoise
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The clinical relevance of detecting minority drug-resistant HIV-1 variants is uncertain.
(400136) Alice Boase
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Dalian notes on rational Pontryagin classes
Creators: name: Weiss, Michael S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 57N55, 57R20, 57R40

description: The rational Pontryagin classes, evaluated on fiber bundles where the fiber is a 2n-dimensional euclidean space, can be nonzero in cohomology dimensions much greater than 4n. This makes a striking contrast with the Pontryagin classes of vector bundles.
description: v2: corrections in appendix A, references added. v3: new appendix B. v4: bibliography updated, appendix A downsized, typos corrected. v5: abstract added. v6: details added. v7: section 2 simplified, minor mistakes corrected. v8: new fonts, erroneous crossrefs corrected. This will be published under another title, "Rational Pontryagin classes of Euclidean fiber bundles"
Fear induced neuronal alterations in a genetic model of depression: An fMRI study on awake animals
Creators: name: King, Jean A.
name: Huang, Wei
name: Heffernan, Meghan E.
name: Zhang, Nanyin
name: Li, Zhixin
name: Overstreet, David H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Previous human imaging studies used facial stimuli to explore the potential association between depression and fear. This study aimed at investigating brain alterations in a rodent model of depression when innate fear was induced in the form of the predator odor trimethylthiazoline (TMT). Flinders sensitive line rats (FSL), a genetic animal model of depression, and their control counterpart Flinders resistant line (FRL), were used in this functional magnetic resonance imaging (fMRI) assessment. Compared to FRL, FSL rats exhibited greater BOLD activation in the cortical amygdala and hypoactivation in the prefrontal cortex in response to TMT, suggesting cortico-amygdalar dysfunction in the depressed strain. In addition, the hyperactivation in the insular cortex in FSL rats may be the basis for enhanced neuronal responses to fear and aversion in depression. These results are evidence for the value of translational models of depression in expanding understanding of the neural circuitries sub-serving common human co-morbidities like depression and fear.
Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders
Creators: name: Bohnen, Nicolaas I.
name: Koeppe, Robert A.
name: Kotagal, Vikas
name: Kaufer, Daniel I.
name: Müller, Martijn L.T.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: There are two major sources of cholinergic projections in the brain. The nucleus basalis of Meynert provides the principal cholinergic input of the cortical mantle and the pedunculopontine nucleus-laterodorsal tegmental complex (PPN-LDTC; hereafter referred to as PPN) provides the major cholinergic input to the thalamus. Cortical cholinergic denervation has previously been shown to be part of Alzheimer and parkinsonian dementia but there is less information about subcortical thalamic cholinergic denervation. We investigated thalamic cholinergic afferent integrity by measuring PPN-Thalamic (PPN-Thal) acetylcholinesterase (AChE) activity via PET imaging in Alzheimer (AD), Parkinson disease without dementia (PD), Parkinson disease with dementia (PDD) and dementia with Lewy bodies (DLB).
A CAPSTONE PROJECT SUBMITTED TOADDIS ABABA UNVERSITY COLLEGE OF HEALTHSCIENCE SCHOOL OF PUBLIC HEALTH IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTERS IN HOSPITAL AND HEALTH CARE ADMINISTRATION
Creators: name: ABEBE BIZU
Publisher: name: Zenodo
Year: 2011

description: The EHSTG Standards, Key Performance Indicators (KPIs) and Ethiopian hospitals alliance for quality

are valuable documents for defining problems and setting objectives that are consistent with national

priorities. The hospital had PMT which continuously evaluate and report to the regional health bureau

monthly based on the key performance indicators and related activities, therefore in the last six-month

midyear/January-June/ 2010 E.C report IPPS/CASH performance was 50%, which has low performance.

The rationale for the establishment of Shoarobit primary Hospital is to reduce mortality, morbidity,

disability and suffering of the people in the catchment area through of effective, efficient, equity and

quality care by providing health promotion and disease preventive, curative and rehabilitative services
Cerebrospinal Fluid and Neuroimaging Biomarker Abnormalities Suggest Early Neurological Injury in a Subset of Individuals During Primary HIV Infection
Creators: name: Meyerhoff, Dieter J.
name: Walter, Rudy
name: Gisslén, Magnus
name: Robertson, Kevin
name: Peterson, Julia
name: Young, Andrew C.
name: Price, Richard W.
name: Hagberg, Lars
name: Peluso, Michael J.
name: Fuchs, Dietmar
name: Cinque, Paola
name: Spudich, Serena
name: Lee, Evelyn
name: Brew, Bruce J.
name: Zetterberg, Henrik
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Background. Cerebrospinal fluid (CSF) and neuroimaging abnormalities demonstrate neuronal injury during chronic AIDS, but data on these biomarkers during primary human immunodeficiency virus (HIV) infection is limited.
Interview Guide on a study: Entropy in the “Entrepot”: Examining the Challenges of Relief Supply chains during COVID-19 Pandemic Relief Item Distribution Operation-2020 in Uganda
Creators: name: Rukundo, Aloysius
name: Aryatwijuka, Wilbroad
Publisher: name: figshare
Year: 2022
Subjects: subject: 130205 Humanities and Social Sciences Curriculum and Pedagogy (excl. Economics, Business and Management)
subject: FOS: Educational sciences

description: It is an interview guide used in collecting the data regarding the paper: Entropy in the “Entrepot”: Examining the Challenges of Relief Supply chains during COVID-19 Pandemic Relief Item Distribution Operation-2020 in Uganda.
A generalization of the Zerilli master variable for a dynamical spherical spacetime
Creators: name: Brizuela, David
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The evolution of polar perturbations on a spherical background spacetime is analyzed. The matter content is assumed to be a massless scalar field.This provides a nontrivial dynamics to the background and the linearized equations of motion become much more involved than in the vacuum case. The analysis is performed in a Hamiltonian framework, which makes explicit the dynamical role of each of the variables. After performing a number of canonical transformations, it is possible to completely decouple the different perturbative degrees of freedom into constrained, pure-gauge and gauge-invariant variables. In particular, two master variables are obtained: one corresponding to the polar mode of the gravitational wave, whereas the other encodes the complete physical information about the perturbative matter degree of freedom. The evolution equations for these master variables are obtained and simplified.
description: 14 pages, accepted for publication in Classical and Quantum Gravity
THE EFFECT OF FOOD AND SERVICE QUALITY ON CUSTOMER SATISFACTION AND LOYALTY IN UZBEK ETHNIC RESTAURANTS
Creators: name: Qoxxorova, Madinaxon
Publisher: name: Zenodo
Year: 2023

description: The aim of this thesis was to investigate the relationship between service quality, customer satisfaction and customer loyalty in Uzbekistan ethnic restaurants in South Korea. A questionnaire based survey was distributed randomly to diners in Uzbek restaurants in Seoul and other cities in Korea. Service quality was measured in terms of SERVQUAL attributes. The key dimensions of customer satisfaction and customer loyalty were identified through literature. The data collected (285 valid questionnaires) were analysed using SPSS and Stata. The findings indicates that service quality influence positively to customer satisfaction. Furthermore, customer satisfaction has a positive effect on customer loyalty. The small size of the sample is the main limitation of this study. The practical implications of this study are founded on the fact that Uzbek ethnic restaurants in South Korea should realize the significant role of service quality in satisfying their customers and making them loyal.
Role of Coagulation Factors in Cerebral Venous Sinus and Cerebral Microvascular Thrombosis
Creators: name: Granger, D. Neil
name: Nagai, Mutsumi
name: Yilmaz, Cigdem Erkuran
name: MacKman, Nigel
name: Esmon, Charles T.
name: Kirchhofer, Daniel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Thrombus formation can occur in both macroscopic and microscopic blood vessels. In the brain, cerebral venous sinus thrombosis (CVST) and focal cortical infarctions can result from the formation of thrombi in these different sized vessels. In this study we define the relative contributions of three major pro- and anti-coagulation pathways (heparin-antithrombin, protein C, and tissue factor (TF)) in the thrombogenic responses that occur in large and small vessels of the brain.
(400137) William Lindsay
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Intersections of multiplicative translates of $3$-adic Cantor sets II: two infinite families
Creators: name: Abram, William C.
name: Bolshakov, Artem
name: Lagarias, Jeffrey C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: Dynamical Systems (math.DS)
subject: Metric Geometry (math.MG)
subject: FOS: Mathematics
subject: 11A63, 11K55, 37B10

description: This paper continues the study of the structure of finite intersections of general multiplicative translates $\mathcal{C}(M_1,\ldots,M_n)=\frac{1}{M_1}Σ_{3,\bar{2}}\cap\cdots\cap\frac{1}{M_n}Σ_{3,\bar{2}}$ for integers $1\leq M_1
description: v5.8, 33 pages, 3 figures, 5 tables
An Experimental Feasibility Study on Robotic Endonasal Telesurgery
Creators: name: Russell, Paul T.
name: Wirz, Raul
name: Alterovitz, Ron
name: Weaver, Kyle D.
name: Webster, Robert J.
name: Gilbert, Hunter
name: Swaney, Philip J.
name: Torres, Luis G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Novel robots have recently been developed specifically for endonasal surgery. They can deliver several thin, tentacle-like surgical instruments through a single nostril. Among the many potential advantages of such a robotic system is the prospect of telesurgery over long distances.
The Neural Circuitry of Autism
Creators: name: Yucel, Gunes H.
name: Cleary, Katherine M.
name: Belger, Aysenil
name: Carpenter, Kimberly L.H.
name: Donkers, Franc C.L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Autism is a complex neurodevelopmental disorder, characterized by deficits in social emotional, and language domains, as well as repetitive restrictive behaviors. The vast heterogeneity of the clinical and behavioral symptoms has made it rather difficult to delineate the neural circuitry affiliated with these domains of dysfunction. The current review aims at broadly outlining the latest research into the neurobiology and neural circuitry underlying the core domains of deficits in autism. We further discuss new avenues of research that can further our understanding of the dimensions of this complex disorder.
(400130) Charles William Boase
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.