cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Closed-Loop Transcranial Alternating Current Stimulation: Towards Personalized Non-invasive Brain Stimulation for the Treatment of Psychiatric Illnesses
Creators: name: Frohlich, Flavio
name: Townsend, Leah
Publisher: name: Springer Nature
Year: 2021

description: Purpose of ReviewThis review introduces closed-loop transcranial alternating current stimulation (tACS), which has the potential to become an effective and safe treatment modality for psychiatric illnesses such as schizophrenia and depression.Recent FindingsThe weak electric fields delivered to the brain by transcranial current stimulation interact in a synergistic manner with endogenous rhythmic brain activity patterns. As a result, the effect of stimulation on neuronal network dynamics is state dependent. Therefore, closed-loop paradigms that measure brain activity and apply targeted stimulation based on these measurements may allow effective modulation by targeted low-amplitude stimulation that is tuned to modulate the measured activity. Few initial studies of such closed-loop tACS have recently documented successful target engagement, mostly for applications that target specific activity patterns during sleep.SummaryGiven the urgent need of novel therapeutic interventions for psychiatric disorders and the recent promising data from initial tACS clinical trials in psychiatry, we propose that closed-loop tACS deserves attention as a promising personalized medicine strategy in psychiatry.
Hydrops triangularis
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Hydrops
Hydrops triangularis

description: Hydrops triangularis (Wagler in Spix, 1824)
Type locality. Lago Tefé, Rio Amazonas, Tefé, state of Amazonas, Brazil.
Distribution. Widespread in the northern portion of South America, in Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Peru, Suriname, Trinidad, and Venezuela, in Amazonian forests (Plt. 292A). In Brazil, recorded widely in Amazonia and marginally in the Cerrado (Plt. 292A) at low elevations (Plt. 292B). Observed in the field in lakes, rivers, and flooded forest and savanna (Scartozzoni, 2010; von May et al., 2019).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 35, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
Establishing targets for advanced HIV disease: A call to action
Creators: name: Kanyama, Cecilia
name: Katureebe, Cordelia
name: Ngwatu, Brian
name: Oladele, Rita
name: Loyse, Angela
name: Mfinanga, Sayoki
name: Amamilo, Ikechukwu
name: Shroufi, Amir
name: Jarvis, Joseph N
name: Meya, David B
name: Tugume, Lillian
name: Phiri, Sam
name: Jibrin, Bilkisu
name: Namuwenge, Proscovia
name: Maokola, Werner
name: Mobolaji-Bello, Mojisola
name: Boulware, David
name: Govender, Nelesh P
name: Rajasingham, Radha
name: Harrison, Thomas S
name: Nabitaka, Vennie
Publisher: name: AOSIS
Year: 2021

description: The World Health Organization (WHO) has published a guideline for the management of individuals with advanced HIV disease (AHD) to reduce HIV-related deaths. The guideline consists of a package of recommendations including interventions to prevent, diagnose and treat common opportunistic infections, including tuberculosis (TB), cryptococcosis and severe bacterial infections, along with rapid initiation of antiretroviral treatment and enhanced adherence support. Currently no clear targets exist for these key interventions. Emerging programmatic data from Uganda, Tanzania and Nigeria suggest that an estimated 80% of eligible people continue to miss the recommended cryptococcal or TB testing, highlighting the remaining challenges to the effective implementation of WHO-recommended AHD packages of care in real-world resource-limited settings. The absence of mortality indicators for the leading causes of HIV-related deaths, because of the lack of mechanisms to ascertain cause of death, has had a negative impact on establishing interventions to reduce mortality. We suggest that setting 95-95-95 targets for CD4 testing, cryptococcal antigen and TB testing, and treatment that are aligned to the WHO AHD package of care would be a step in the right direction to achieving the greater goal of the WHO End TB strategy and the proposed new strategy to end cryptococcal meningitis deaths. However, these targets will only be achieved if there is healthcare worker training, expanded access to bedside point-of-care diagnostics for hospitalised patients and those in outpatient care who meet the criteria for AHD, and health systems strengthening to minimise delays in initiating the WHO-recommended therapies for TB and cryptococcal disease.
Pseudoeryx plicatilis
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Pseudoeryx
Pseudoeryx plicatilis

description: Pseudoeryx plicatilis (Linnaeus, 1758)
Type locality. “ Ternataeis ” (= Ternate island, Indonesia; in error).
Distribution. Known from Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Paraguay, Peru, Suriname, and Venezuela (Plt. 293A). In Brazil, widespread in Amazonia and Pantanal, with marginal records in the Cerrado (Plt. 293A), at low elevations (Plt. 293B). Observed in the field in wetlands and seasonally flooded areas (Strüssmann and Sazima, 1993; Giraudo and Scrocchi, 2002; FranÇa et al., 2006; Scartozzoni et al., 2010).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 35, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
D1.4: SUPER MoRRI final report
Creators: name: Lindner, Ralf
name: Woolley, Richard
name: Berghäuser, Hendrik
name: Brasil, André
name: Bührer-Topçu, Susanne
name: Flipse, Steven
name: Griessler, Erich
name: Kjeldager Ryan, Thomas
name: Llorente Lopez, Carolina
name: Meijer, Ingeborg
name: Revuelta de la Poza, Gema
name: Rommetveit, Kjetil
name: Stack, Shauna
name: Strand, Roger
name: Yaghmaei, Emad
Publisher: name: Zenodo
Year: 2024

description: This final SUPER MoRRI deliverable summarises all the results from the project and gives overall recommendations based on the project's insights.
title: Exploring organic, redox-active materials for electrolytic hydrogen production and electrochemical energy storage
Creators: name: Kirkaldy, Niall
Publisher: name: University of Glasgow
Year: 2018
Subjects: subject: Hydrogen, H2, energy storage, electrochemistry, redox, chemistry, batteries, renewable energy, inorganic chemistry, PEM electrolyser, water splitting.

description: Abstract not currently available.
title: Marriage postponement and fertility decline in Iran: accounting for socio-economic and cultural changes in time and space
Creators: name: Torabi, F
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2011

description: This thesis examines the patterns and determinants of the marriage postponement and fertility decline experienced by Iranian women during the last two decades of the twentieth century. The thesis accounts for temporal changes in the socio-economic context of marriage and childbearing (e.g. improvement in education, urbanisation, economic fluctuations, etc.) and examines the marriage timing and fertility patterns of the cohorts of women who contributed to the recent marriage and fertility changes in order to provide more insight into the demographic behaviour of women with specific life course experiences. A topic of specific interest is the variation between the ethnic groups in Iran.
The findings suggest that the recent marriage postponement was related to improvements in women's education and restrictions in the availability of suitable spouses (marriage market), with the former being the only factor contributing to the marriage delay of consecutive (1971-75 and 1976-80) birth cohorts. The recent decline in the probability of second and third conceptions was related to improvements in women's educational level, reductions in child mortality, and improvements in children's enrolment in education. The contribution of son preference to the probability of conception of a second child and the specific impact of urbanisation and industrialisation on the recent marriage and fertility changes were also notable. Different socio-economic factors were found responsible for the decline in the probability of a second conception across consecutive cohorts. of women (those who became exposed to the risk of childbearing in 1986-90 and 1991-95), whereas cohort differences in the probability of a third conception was not generally related to socio-economic forces, probably reflecting a common preference for stopping at two children. The findings also highlight the role of cultural factors associated with ethnicity in shaping differential patterns of marriage timing and suggest that ethnic differences in fertility are strongly related to ethnic differences in socio-economic attributes.
Reactions of Mesityl Azide with Ferrocene-Based N-Heterocyclic Germylenes, Stannylenes and Plumbylenes, Including PPh₂-Functionalised Congeners
Creators: name: Guthardt, Robin
name: Oetzel, Lisa
name: Lang, Tobias
name: Bruhn, Clemens
name: Siemeling, Ulrich
Publisher: name: Universität Kassel
Year: 2022
Subjects: subject: azides
subject: carbene homologues
subject: metallocenes
subject: subvalent compounds
subject: tetrylenes
subject: 540
subject: Azide
subject: Chemische Synthese
subject: Eisenkomplexe
subject: Chemische Reaktion
subject: Staudinger-Reaktion
subject: Carbene

description: Gefördert im Rahmen des Projekts DEAL
Five years after Treat All implementation: Botswana's HIV response and future directions in the era of COVID-19
Creators: name: Selato, Robert
name: Mmelesi, Mpho
name: Muthoga, Charles
name: Phillips, Heston
name: Nkomo, Bornapate
name: Ratladi, Siphiwe
name: Jefferis, Keith
name: Avalos, Ava
name: Stover, John
name: Ramaabya, Dinah
name: Jarvis, Joseph N.
Publisher: name: AOSIS
Year: 2021

description: BACKGROUND: As the relentless coronavirus disease-2019 (COVID-19) pandemic continues to spread across Africa, Botswana could face challenges maintaining the pathway towards control of its HIV epidemic. OBJECTIVE: Utilising the Spectrum GOALS module (GOALS-2021), the 5-year outcomes from the implementation of the Treat All strategy were analysed and compared with the original 2016 Investment Case (2016-IC) projections. Future impact of adopting the new Joint United Nations Programme on HIV/AIDS (UNAIDS) Global AIDS Strategy (2021-2026) targets and macroeconomic analysis estimating how the financial constraints from the COVID-19 pandemic could impact the available resources for Botswana's National HIV Response through 2030 were also considered. METHOD: Programmatic costs, population demographics, prevention and treatment outputs were determined. Previous 2016-IC data were uploaded for comparison, and inputs for the GOALS, AIM, DemProj, Resource Needs and Family Planning modules were derived from published reports, strategic plans, programmatic data and expert opinion. The economic projections were recalibrated with consideration of the impact of the COVID-19 pandemic. RESULTS: Decreases in HIV infections, incidence and mortality rates were achieved. Increases in laboratory costs were offset by estimated decreases in the population of people living with HIV (PLWH). Moving forward, young women and others at high risk must be targeted in HIV prevention efforts, as Botswana transitions from a generalised to a more concentrated epidemic. CONCLUSION: The Treat All strategy contributed positively to decreases in new HIV infections, mortality and costs. If significant improvements in differentiated service delivery, increases in human resources and HIV prevention can be realised, Botswana could become one of the first countries with a previously high-burdened generalised HIV epidemic to gain epidemic control, despite the demands of the COVID-19 pandemic.
Ditaxodon taeniatus
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Ditaxodon
Ditaxodon taeniatus

description: Ditaxodon taeniatus (Peters in Hensel, 1868)
Type locality. Porto Alegre, Rio Grande do Sul, Brazil. Possibly in error (Bérnils et al., 2008).
Distribution. Endemic to Brazil (Plt. 294A). Known from few and scattered records,mostly in Araucaria Forest, and marginally in the Cerrado and Atlantic Forest (Plt. 294A), mostly at high elevations (Plt. 294B). Observed in the field in montane grassland (Thomas et al., 2006).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 35, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
Philodryas aestiva
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Philodryas
Philodryas aestiva

description: Philodryas aestiva (Duméril et al., 1854)
Type locality. Santa Catarina, Brazil.
Distribution. Known from the southern portion of South America, in Argentina, Brazil, Paraguay, and Uruguay (Plt. 295A). In Brazil, widespread in the southern portion of the Atlantic Forest, Pampas Grasslands, Araucaria Forest, and Cerrado, with marginal isolated records in Pantanal and upland areas in the Caatinga (Plt. 295A). Recorded mostly in low areas in the southern part of the range, and in intermediate to high elevation areas near its northern limits (Plt. 295B). Observed in the field in grassland and savanna (Vaz-Silva et al., 2007; Ghizoni-Jr. et al., 2009; Valdujo et al., 2009; Freitas et al., 2012).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 35, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
Metabolic Phenotype of Wild-Type and As3mt-Knockout C57BL/6J Mice Exposed to Inorganic Arsenic: The Role of Dietary Fat and Folate Intake
Creators: name: Tejan-Sie, Ahmad
name: Huang, Madelyn C
name: Douillet, Christelle
name: Krupenko, Sergey A
name: Styblo, Miroslav
name: Dover, Ellen N
name: Zhang, Chongben
name: Beck, Rowan
Publisher: name: Environmental Health Perspectives
Year: 2018

description: BACKGROUND: Inorganic arsenic (iAs) is a diabetogen. Interindividual differences in iAs metabolism have been linked to susceptibility to diabetes in iAs-exposed populations. Dietary folate intake has been shown to influence iAs metabolism, but to our knowledge its role in iAs-associated diabetes has not been studied. OBJECTIVE: The goal of this study was to assess how folate intake, combined with low-fat (LFD) and high-fat diets (HFD), affects the metabolism and diabetogenic effects of iAs in wild-type (WT) mice and in As3mt-knockout (KO) mice that have limited capacity for iAs detoxification. METHODS: Male and female WT and KO mice were exposed to 0 or [Formula: see text] iAs in drinking water. Mice were fed the LFD containing [Formula: see text] or [Formula: see text] folate for 24 weeks, followed by the HFD with the same folate levels for 13 weeks. Metabolic phenotype and iAs metabolism were examined before and after switching to the HFD. RESULTS: iAs exposure had little effect on the phenotype of mice fed LFD regardless of folate intake. High folate intake stimulated iAs metabolism, but only in WT females. KO mice accumulated more fat than WT mice and were insulin resistant, with males more insulin resistant than females despite similar %fat mass. Feeding the HFD increased adiposity and insulin resistance in all mice. However, iAs-exposed male and female WT mice with low folate intake were more insulin resistant than unexposed controls. High folate intake alleviated insulin resistance in both sexes, but stimulated iAs metabolism only in female mice. CONCLUSIONS: Exposure to [Formula: see text] iAs in drinking water resulted in insulin resistance in WT mice only when combined with a HFD and low folate intake. The protective effect of high folate intake may be independent of iAs metabolism, at least in male mice. KO mice were more prone to developing insulin resistance, possibly due to the accumulation of iAs in tissues. https://doi.org/10.1289/EHP3951.
Translator Exposure APIs: Open Access to Data on Airborne Pollutant Exposures, Roadway Exposures, and Socio-Environmental Exposures and Use Case Application
Creators: name: Xu, Hao
name: Garantziotis, Stavros
name: Xue, William
name: Appold, Stephen
name: Stillwell, Lisa
name: Arunachalam, Saravanan
name: Cox, Steven
name: Fecho, Karamarie
name: Ahalt, Stanley C.
name: Valencia, Alejandro
name: Schurman, Shepherd H.
name: Schmitt, Charles P.
Publisher: name: MDPI
Year: 2020

description: Environmental exposures have profound effects on health and disease. While public repositories exist for a variety of exposures data, these are generally difficult to access, navigate, and interpret. We describe the research, development, and application of three open application programming interfaces (APIs) that support access to usable, nationwide, exposures data from three public repositories: airborne pollutant estimates from the US Environmental Protection Agency; roadway data from the US Department of Transportation; and socio-environmental exposures from the US Census Bureau's American Community Survey. Three open APIs were successfully developed, deployed, and tested using random latitude/longitude values and time periods as input parameters. After confirming the accuracy of the data, we used the APIs to extract exposures data on 2550 participants from a cohort within the Environmental Polymorphisms Registry (EPR) at the National Institute of Environmental Health Sciences, and we successfully linked the exposure estimates with participant-level data derived from the EPR. We then conducted an exploratory, proof-of-concept analysis of the integrated data for a subset of participants with self-reported asthma and largely replicated our prior findings on the impact of select exposures and demographic factors on asthma exacerbations. Together, the three open exposures APIs provide a valuable resource, with application across environmental and public health fields.
Philodryas agassizii
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Philodryas
Philodryas agassizii

description: Philodryas agassizii (Jan, 1863)
Type locality. “ Uruguay ” (in error, according to Wallach et al., 2014). Corrected to Paraguay fide original data tag and MCZ Catalogue (Wallach et al., 2014).
Distribution. Known from the southern portion of South America, in Argentina, Brazil, Paraguay, and Uruguay (Plt. 296A). In Brazil, widespread in Pampas Grasslands and the southern portion of the Cerrado, with marginal records in Araucaria Forest, Atlantic Forest, and Caatinga (Plt. 296A). Recorded mostly in low areas in the southern part of the range, and in intermediate to high elevation areas near its northern limits (Plt. 296B). Observed in the field in grassland and savanna (Nogueira, 2001; Marques et al., 2006; Winck et al., 2007).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 35, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
title: Statistical methods for cost-effectiveness analysis that use cluster-randomised trials
Creators: name: Gomes, Manuel
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2012

description: This thesis considers alternative statistical methods for cost-effectiveness analysis (CEA) that use cluster randomised trials (CRTs). The thesis has four objectives: firstly to develop criteria for identifying appropriate methods for CEA that use CRTs; secondly to critically appraise the methods used in applied CEAs that use CRTs; thirdly to assess the performance of alternative methods for CEA that use CRTs in settings where baseline covariates are balanced; fourthly to compare statistical methods that adjust for systematic covariate imbalance in CEA that use CRTs.
The thesis developed a checklist to assess the methodological quality of published CEAs that use CRTs. This checklist was informed by a conceptual review of statistical methods, and applied in a systematic literature review of published CEAs that use CRTs. The review found that most studies adopted statistical methods that ignored clustering or correlation between costs and health outcomes.
A simulation study was conducted to assess the performance of alternative methods for CEA that use CRTs across different circumstances where baseline covariates are balanced. This study considered: seemingly unrelated regression (SUR) and generalised estimating equations (GEEs), both with a robust standard error; multilevel models (MLMs) and a non-parametric 'two-stage' bootstrap (TS8). Performance was reported as, for example, bias and confidence interval (Cl) coverage of the incremental net benefit. The MLMs and the TSB performed well across all settings; SUR and GEEs reported poor Cl coverage in CRTs with few clusters. 
The thesis compared methods for CEA that use CRTs when there are systematic differences in baseline covariates between the treatment groups. In a case study and further simulations, the thesis  considered SUR, MLMs, and TSB combined with SUR to adjust for covariate imbalance. The case-study showed that cost-effectiveness results can differ according to adjustment method. The simulations reported that MLMs performed well across all settings, and unlike the other methods, provided Cl coverage close to nominal levels, even with few clusters and unequal cluster sizes.
The thesis concludes that MLMs are the most appropriate method across the circumstances considered. This thesis presents methods for improving the quality ofCEA that use CRTs, to help future studies provide a sound basis for policy making.
WORKING ON SUBORDINATE WORD RELATIONSHIPS WHEN STUDYING THE TOPIC OF "PREPOSITION"
Creators: name: Holikova, Gulnoza
name: Nosirjonova, Zarinabonu
name: Komiljonova, Mohidilhon
name: Popova, E.I.
Publisher: name: Zenodo
Year: 2024

description: The article examines the heterogeneous nature of syntactic relations in a sentence. Their dependence on syntactic functions, on lexical and grammatical features of a word, on syntactic positions of connecting word forms is substantiated.
Philodryas argentea
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Philodryas
Philodryas argentea

description: Philodryas argentea (Daudin, 1803)
Type locality. Unknown.
Distribution. Known from Brazil, Colombia, French Guiana, Peru, Suriname and Venezuela, in Amazonian forest (Plt. 297A).In Brazil,widespread in Amazonia (Plt. 297A), mostly at low elevations (Plt. 297B). Observed in the field in forest (Martins and Oliveira, 1998; Rodrigues et al., 2010; Ávila and Kawashita-Ribeiro, 2011; Bernarde et al., 2011).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 35, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
Open Application of Statistical and Machine Learning Models to Explore the Impact of Environmental Exposures on Health and Disease: An Asthma Use Case
Creators: name: Haaland, Perry
name: Peden, David B.
name: Lan, Bo
name: Sharma, Priya
name: Xu, Hao
name: Krishnamurthy, Ashok
name: Fecho, Karamarie
name: Schmitt, Patrick L.
name: Sinha, Meghamala
Publisher: name: MDPI
Year: 2021

description: ICEES (Integrated Clinical and Environmental Exposures Service) provides a disease-agnostic, regulatory-compliant approach for openly exposing and analyzing clinical data that have been integrated at the patient level with environmental exposures data. ICEES is equipped with basic features to support exploratory analysis using statistical approaches, such as bivariate chi-square tests. We recently developed a method for using ICEES to generate multivariate tables for subsequent application of machine learning and statistical models. The objective of the present study was to use this approach to identify predictors of asthma exacerbations through the application of three multivariate methods: conditional random forest, conditional tree, and generalized linear model. Among seven potential predictor variables, we found five to be of significant importance using both conditional random forest and conditional tree: prednisone, race, airborne particulate exposure, obesity, and sex. The conditional tree method additionally identified several significant two-way and three-way interactions among the same variables. When we applied a generalized linear model, we identified four significant predictor variables, namely prednisone, race, airborne particulate exposure, and obesity. When ranked in order by effect size, the results were in agreement with the results from the conditional random forest and conditional tree methods as well as the published literature. Our results suggest that the open multivariate analytic capabilities provided by ICEES are valid in the context of an asthma use case and likely will have broad value in advancing open research in environmental and public health.
Philodryas arnaldoi
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Philodryas
Philodryas arnaldoi

description: Philodryas arnaldoi (Amaral, 1933)
Type locality. São Bento do Sul, state of Santa Catarina, Brazil.
Distribution. Endemic to Brazil (Plt. 298A). Recorded in Araucaria Forest and marginally in Atlantic Forest and one isolated record in the Cerrado (Plt. 298A), mostly at intermediate to high elevations (Plt. 298B). Observed in the field in forest (Di-Bernardo et al., 2003; Morato, 1995; Morato et al., 2003; Bérnils et al., 2007).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 36, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
title: What factors influence socioeconomic inequalities in colorectal cancer survival?
Creators: name: Shack, Lg
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2009

description: Colorectal cancer treatment and survival is improving, but deprived patients continue to receive less than optimal treatment and have lower survival than affluent patients. Population-based data on all patients diagnosed with colorectal cancer in the North West (n=29,563) was linked to hospital admissions (n=6 million) to provide complete information on cancer diagnosis, treatment and other comorbid conditions. In order to handle incomplete data, particularly for stage at diagnosis, multiple imputation was used.
Socioeconomic inequalities in survival have been attributed to deprived patients presenting at a more advanced stage or with more comorbid conditions than affluent. In this research there were no socioeconomic variations in stage at diagnosis but deprived patients did have higher levels of comorbidity, which may limit their treatment options. Even after taking clinical and demographic factors into account, deprived patients still received less adjuvant therapy, surgery from high-volume surgeons and treatment in compliance with clinical guidance
Socioeconomic inequalities in survival were substantial at one year after diagnosis and could not be explained by clinical or demographic factors, such as stage and  comorbidity. Even when deprived patients did receive the same treatment regime or surgery from a higher-volume hospital or higher-volume surgeon survival was lower. The factors contributing to these inequalities in treatment are complex including physical, social, lifestyle and clinical domains. Ensuring equal access to services and equal improvement in survival across all social groups will be a continuing challenge for the NHS. Ultimately, a universal health-care system may not be able to achieve equal survival, because of external factors that cannot be controlled, but ensuring equitable access would be expected to greatly reduce the inequalities in colorectal cancer survival.
Philodryas georgeboulengeri Grazziotin 2012
Creators: name: Nogueira, Cristiano C.
name: Argôlo, Antonio J. S.
name: Arzamendia, Vanesa
name: Azevedo, Josué A.
name: Barbo, Fausto E.
name: Bérnils, Renato S.
name: Bolochio, Bruna E.
name: Borges-Martins, Marcio
name: Brasil-Godinho, Marcela
name: Braz, Henrique
name: Buononato, Marcus A.
name: Cisneros-Heredia, Diego F.
name: Colli, Guarino R.
name: Costa, Henrique C.
name: Franco, Francisco L.
name: Giraudo, Alejandro
name: Gonzalez, Rodrigo C.
name: Guedes, Thaís
name: Hoogmoed, Marinus S.
name: Marques, Otavio A. V.
name: Montingelli, Giovanna G.
name: Passos, Paulo
name: Prudente, Ana L. C.
name: Rivas, Gilson A.
name: Sanchez, Paola M.
name: Serrano, Filipe C.
name: Silva Jr., Nelson J.
name: Strüssmann, Christine
name: Vieira-Alencar, João Paulo S.
name: Zaher, Hussam
name: Sawaya, Ricardo J.
name: Martins, Marcio
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Reptilia
Squamata
Colubridae
Philodryas
Philodryas georgeboulengeri

description: Philodryas georgeboulengeri Grazziotin et al., 2012
Type locality. Río Mamoré, Trinidad, Bolivia.
Distribution. Known from Bolivia, Brazil, and Peru (Plt. 299A). In Brazil, recorded in southwestern Amazonia and Beni savannas (Plt. 299A), mostly at low elevations (Plt. 299B). Observed in the field in forest (Bernarde et al., 2011).
description: Published as part of Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J. & Martins, Marcio, 2019, Atlas of Brazilian Snakes: Verified Point-Locality Maps to Mitigate the Wallacean Shortfall in a Megadiverse Snake Fauna, pp. 1-274 in South American Journal of Herpetology 14 (s 1) on page 36, DOI: 10.2994/SAJH-D-19-00120.1, http://zenodo.org/record/10061686
title: Pandemic perpardeness and multi-sectoral zoonosis risk management: a case study of avian and human influenza prevention and control policy development across
Creators: name: Mwacalimba, KM
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2011

description: Emerging zoonoses have unique consequences for the animal health, public health and trade sectors. This study examined the links between policy. zoonoses, and risk in Zambia and assessed the feasibility of a World Organisation for Animal Health (OlE) risk analysis in informing risk management in this context.
The research was a qualitative case study drawing on: in-depth interviews with key informants; informal interviews; documentary review and observation. Snowball sampling was used to select informants directly involved in avian (H5Nl) and human influenza policy development and/or livestock trade policy implementation at national level. A chronology of avian and human influenza policy development in Zambia over the period 2005-2009 was constructed. Policy process and interpretivist policy analysis theories guided analysis.
In this resource-constrained setting, external international agendas were found to have considerable influence on policy. National stakeholders initially framed H5Nl as an imminent threat and largely animal health problem. This prioritized the involvement of health and agricultural actors in the policy process and excluded those from trade and other key sectors. H5Nl was a plausible threat to agriculture, and a potential threat to human health, but perceptions of risk presented real economic repercussions for the poultry industry. Despite challenges in coordinating the policy response, the policy process had tangible benefits for Zambia in terms of pandemic preparedness and for raising the profile of the previously underrecognised poultry industry.
This study suggests the weighing of both local policy and ecological configurations in assessment of risk and the design of zoonotic disease mitigation policies. While feasible, the merits of an OlE risk analysis in informing policy development in this context would be enhanced by a careful consideration and inclusion of policy processes. An objective and discursive approach to analysis of risk, appropriately communicated to stakeholders, would improve collaboration in disease management across sectors.
title: Drug-resistant tuberculosis in children
Creators: name: Seddon, Ja
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2012

description: The number of children globally who develop drug-resistant tuberculosis is unclear, in part due to diagnostic challenges and limited resistance testing, and in part because recording and reporting is not comprehensive. Large numbers of children, however, are exposed to drug resistant bacilli each year and it is clear that the very young and those immune-compromised are vulnerable to developing disease. Few studies have looked at the progression from exposure to infection or from infection to disease in the child contacts of adults with drug-resistant tuberculosis. It is uncertain which factors influence this progression and also whether any interventions can prevent it. Finally, few studies have analysed the presentation, treatment and outcome of children with disease. This thesis starts by reviewing what is published regarding drug-resistant tuberculosis in children. This includes systematic reviews of the management of children exposed to drug resistant tuberculosis as well as the management of those with multi drug-resistant tuberculosis disease. It reviews what is known regarding the second-line tuberculosis drugs in children and then clarifies the definitions that are used throughout the rest of the work. The thesis then systematically examines each of the stages from infection to disease with a series of inter-related studies. The first study attempts to quantify the burden of drug resistance in the context that the work is carried out. The following study investigates the risk factors for infection and prevalent disease in children exposed to a multi drug-resistant tuberculosis source case. This is followed by two studies which explore the transmission of drug-resistant bacilli from adults to children. The identification and referral patterns and obstacles to referral for exposed children are examined through operational studies that include qualitative and quantitative components. A descriptive cohort study assesses the toxicity and efficacy of a standardised preventive treatment regimen given to child contacts. The final part of the thesis includes a series of studies to investigate the treatment of drug resistant tuberculosis disease in children and the adverse effects of the second-line medications.