cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes
Creators: name: Zheng, Wang
name: Chen, Qianping
name: Liu, Hongxia
name: Zeng, Liang
name: Zhou, Yuchuan
name: Liu, Xinglong
name: Bai, Yang
name: Zhang, Jianghong
name: Pan, Yan
name: Shao, Chunlin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology

description: Glioblastoma multiforme (GBM) is the most common brain malignancy insensitive to radiotherapy (RT). Although macroautophagy/autophagy was reported to be a fundamental factor prolonging the survival of tumors under radiotherapeutic stress, the autophagic biomarkers coordinated to radioresistance of GBM are still lacking in clinical practice. Here we established radioresistant GBM cells and identified their protein profiles using tandem mass tag (TMT) quantitative proteomic analysis. It was found that SDC1 and TGM2 proteins were overexpressed in radioresistant GBM cells and tissues and they contributed to the poor prognosis of RT. Knocking down SDC1 and TGM2 inhibited the fusion of autophagosomes with lysosomes and thus enhanced the radiosensitivity of GBM cells. After irradiation, TGM2 bound with SDC1 and transported it from the cell membrane to lysosomes, and then bound to LC3 through its two LC3-interacting regions (LIRs), coordinating the encounter between autophagosomes and lysosomes, which should be a prerequisite for lysosomal EPG5 to recognize LC3 and subsequently stabilize the STX17-SNAP29-VAMP8 QabcR SNARE complex assembly. Moreover, when combined with RT, cystamine dihydrochloride (a TGM2 inhibitor) extended the lifespan of GBM-bearing mice. Overall, our findings demonstrated the EPG5 tethering mode with SDC1 and TGM2 during the fusion of autophagosomes with lysosomes, providing new insights into the molecular mechanism and therapeutic target underlying radioresistant GBM.Abbreviations: BafA1: bafilomycin A1; CQ: chloroquine; Cys-D: cystamine dihydrochloride; EPG5: ectopic P-granules 5 autophagy tethering factor; GBM: glioblastoma multiforme; GFP: green fluorescent protein; LAMP2: lysosomal associated membrane protein 2; LIRs: LC3-interacting regions; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; NC: negative control; RFP: red fluorescent protein; RT: radiotherapy; SDC1: syndecan 1; SNAP29: synaptosome associated protein 29; SQSTM1/p62: sequestosome 1; STX17: syntaxin 17; TGM2: transglutaminase 2; TMT: tandem mass tag; VAMP8: vesicle associated membrane protein 8; WT: wild type
On the usefulness of four in vitro methods in assessing the intraluminal performance of poorly soluble, ionisable compounds in the fasted state
Creators: name: O'Dwyer, Patrick J.
name: Box, Karl J.
name: Imanidis, Georgios
name: Vertzoni, Maria
name: Reppas, Christos
Publisher: name: Elsevier
Year: 2022
Subjects: subject: 600 - Technik, Medizin, angewandte Wissenschaften

description: A small-scale two-stage biphasic system, a small-scale two-stage dissolution-permeation system, the Erweka mini-paddle apparatus, and the BioGIT system were evaluated for their usefulness in assessing the intraluminal performance of two low solubility drugs in the fasted state, one with weakly acidic properties (tested in a salt form, diclofenac potassium) and one with weakly alkaline properties [ritonavir, tested as an amorphous solid dispersion (ASD) formulation]. In all in vitro methods, an immediate-release tablet and a powder formulation of diclofenac potassium were both rapidly dissolved in Level II biorelevant media simulating the conditions in the upper small intestine. Physiologically based biopharmaceutics (PBB) modelling for the tablet formulation resulted in a successful simulation of the average plasma profile in adults, whereas for the powder formulation modelling indicated that gastric emptying and transport through the intestinal epithelium limit the absorption rates. Detailed information on the behaviour of the ritonavir ASD formulation under both simulated gastric and upper small intestinal conditions were crucial for understanding the luminal performance. PBB modelling showed that the dissolution and precipitation parameters, estimated from the Erweka mini-paddle apparatus data and the small-scale two-stage biphasic system data, respectively, were necessary to adequately simulate the average plasma profile after administration of the ritonavir ASD formulation. Simulation of the gastrointestinal transfer process from the stomach to the small intestine was necessary to evaluate the effects of hypochlorhydric conditions on the luminal performance of the ritonavir ASD formulation.
title: South Bay Salt Ponds Restoration Project Phase 2
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the South Bay Salt Ponds Restoration Project Phase 2 in San Francisco Bay
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2018

description: ESA Section 7 Consultation ; WCRO-2017-01436
title: Plains Products Martinez 2017 Wharf Repairs and Retrofit
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the Plains Martinez 2017 Wharf Repairs and Retrofit Project in Suisun Bay (Corps File No. 2013-00172S)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2018

description: ESA Section 7 Consultation ; WCRO-2017-01435
title: Seaplane Lagoon Ferry Terminal Project
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the Seaplane Lagoon Ferry Terminal Project in San Francisco Bay (Corps File No. 2015-00460S)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2017

description: ESA Section 7 Consultation ; WCRO-2016-00526
title: ADCO, Cartulaire de Saint-Étienne de Dijon (XIVe siècle), Cart. 24 (G 137), 31 folios, f. 0055
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Saint-Étienne de Dijon (XIVe siècle), Archives départementales de la Côte-d'Or, Cart. 24 (G 137), 31 folios, f. 0055, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Saint-Étienne de Dijon (XIVe siècle), Archives départementales de la Côte-d'Or, Cart. 24 (G 137), 31 folios, f. 0055, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Environmental Distribution of Mycobacterium avium paratuberculosis (MAP) on Michigan Dairy Farms
Creators: name: Pillars, R. B.
name: Kaneene, J. B.
name: Grooms, D. L.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Johne's disease (JD) is an important infectious disease of cattle caused by Mycobacterium avium subspecies paratuberculosis (MAP). It is estimated that over 50% of US dairy herds are infected with MAP. Environmental contamination with MAP is considered the major reservoir of infection for susceptible cattle. While MAP does not multiply in the environment, it can persist for months in manure, lagoons, manure packs--areas that are found in abundance on most dairy farms--even in below-freezing temperatures. Very little information is published on distribution of MAP on dairy farms. The objectives of this study were to: 1) perform serial environmental culturing on six Michigan dairy herds, enrolled in a JD control program over several years; 2) characterize the distribution of MAP contamination on dairy farms; and 3) determine if and how that distribution changes as herd fecal culture prevalence changes.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Effect of Maternity Pen Management on Morbidity and Mortality in Dairy Heifer Calves from Birth to 90 Days of Life
Creators: name: Pithua, P.
name: Wells, S. J.
name: Godden, S. M.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Risk factors for calf morbidity and mortality have been well characterized. Type of maternity housing and where calves are born have been shown to influence the likelihood of morbidity and mortality suffered by calves during the preweaning period. Proper management and hygiene of maternity pens may help reduce the frequency of early calfhood diseases in calves. The objective of this study was to determine whether heifer calves born in individual maternity pens will have a lower risk for experiencing calfhood diseases versus heifer calves born in a multiple cow maternity housing area.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
A Preliminary Study on the Effect of Intra-uterine Infusion of Sodium Ceftiofur on Chronic Uterine Infections of Holstein Cows
Creators: name: Havaresht, P.
name: Moradi, A.
name: Kasravi, R.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Cows suffering from postpartum endometritis which may not be treated with conventional treatments, and thus may have long days-in-milk (DIM), are candidates for disposal from the herd. The aim of this study was to treat such animals with only one intra-uterine (IU) infusion of ceftiofur to keep them in the herd.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
A reinterpreted-texture strategy for rendering point symbols based on graphics processing unit
Creators: name: Shu, Yucheng
name: Tang, Zihao
name: Yue, Songshan
name: Wen, Yongning
name: Chen, Min
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The increasing demands of presenting large numbers of points in maps have promoted the progress of rendering point symbols in GPUs. Although the drawing efficiency issue can be handled with texture mapping methods, the rendering quality problem due to the fixed resolution that affects map renders’ visual experiences remains. The method of directly drawing vector paths of a point symbol can be used to satisfy the sharper effect of point symbols. However, it requires high memory cost and affects the drawing efficiency. This paper proposes a point symbol rendering method using the idea of reinterpreted textures. The rendering data used in this method are based on vectors to achieve refined results. Vector properties of symbols are encoded and organized into the texture structure with specific layout schemes. In the rendering phase, an instanced pipeline is launched to accept the texture and decode the required attributes. The proposed method takes advantage of fast access and continuity of textures while retaining geometric transformations. These features allow all symbols to be drawn in one single draw call and rotated or scaled arbitrarily. Experiments on drawing quality and efficiency demonstrate that the proposed method achieves fast and stable performance while maintaining the rendering quality.
title: Plains Products Marine Terminal Seismic Retrofit
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the Plains Products Marine Terminal Seismic Retrofit and Corrosion Mitigation Project (Corps File No. 2013-00172N)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2017

description: ESA Section 7 Consultation ; WCRO-2016-00525
title: Reinitiation Mare Island Shipyard Dry Docks
title: Endangered Act Section 7(a)(2) Biological Opinion for the Mare Island Maintenance Dredging and Dry Dock Operations in San Francisco Bay, Reinitiation of Consultation (Corps File No. 2008-00311)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2017

description: ESA Section 7 Consultation ;  WCRO-2015-00058
A New Device for the Collection of Bovine Semen
Creators: name: Dehn, C. A.
name: Prien, S. D.
name: Johnson, D. L.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: In general, the act of collecting semen for artificial insemination takes semen from its protected storage environment in the male and thrusts it into the unprotected environment of a specimen collection tube. Even with rapid processing, this leads to drastic shifts in temperature and pH, resulting in a quick deterioration of semen parameters and programmed cell death. This laboratory has developed a species-specific modified collection device (MCD), which was designed to optimize semen parameters by controlling temperature, pH and osmotic stress. In previous studies in the equine, canine, ovine and humans, using the new collection container/technique has resulted in improved semen parameters which are maintained over extended periods of time when compared to the traditional collection methods. Further, in a breeding trail in the equine, fertility rates of fresh semen were maintained for extended periods of time over the control. The objective of the current study was to further investigate the usefulness of the modified device in improving semen parameters and fertility rates in the bovine.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Reproductive biology of Melanophryniscus montevidensis (Anura: Bufonidae) from Uruguay: reproductive effort, fecundity, sex ratio and sexual size dimorphism
Creators: name: Pereira, Gisela
name: Maneyro, Raúl
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology

description: We analyzed the reproductive traits of a population of Melanophryniscus montevidensis. The reproductive events were associated to rainfalls. Males called from dawn to late night, were more abundant than females, and adopted alternative tactics to find partners (active search). Females were larger than males, and had mature oocytes and lipid reserves after spawning; they showed no association between size and fecundity. As an explosive breeder, females are prepared all year long for reproduction. Several individuals revealed high site-fidelity for breeding. Knowledge about breeding pattern could help to propose suitable and efficient in situ conservation measures for this endangered species.
title: Bear Gulch Upper Diversion Fish Passage Project
title: Endangered Act Section 7(a)(2) Biological Opinion for the Bear Gulch Upper Diversion Fish Passage Project in the Town of Woodside, San Mateo County, California (Corps File No. 2016-00145S)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2017

description: ESA Section 7 Consultation ; WCRO-2016-00524
SELLF. Unterrichtsentwicklung in der Grundausbildung anlegen nach dem Luuise-Prinzip
Creators: name: Gobat, Franziska
name: Raaflaub, Meike
name: Reber, Brigitte
name: Pirani, Kathrin
Publisher: name: PH Bern
Year: 2019
Subjects: subject: SELLF
subject: Luuise
subject: Fremdsprachen
subject: Fachdidaktische Lernprozesse
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Wie kann fremdsprachendidaktische Unterrichtsentwicklung bereits in der Ausbildung von Lehrpersonen ressourcenschonend angelegt werden? Inwieweit können durch individualisierte Entwicklungsprojekte fachdidaktische Lernprozesse praxisnah gefördert werden? Ausgehend von diesen Fragestellungen entstand ein Zusammenarbeitsprojekt der Pädagogischen Hochschule Bern (PHBern) und der Pädagogischen Hochschule der Fachhochschule Nordwestschweiz (PH FHNW). Das aus der Weiterbildung stammende Unterrichtsentwicklungsverfahren Luuise1 (Lehrpersonen unterrichten und untersuchen integriert, sichtbar und effektiv) wurde für den Einsatz in der fremdsprachendidaktischen Grundausbildung auf Sekundarstufe I der PHBern adaptiert und während des Studienjahres 2019/20 evaluiert. Der Beitrag präsentiert das im Zuge des Kooperationsprojektes entwickelte Verfahren SELLF (Studierende entwickeln lehrend und lernend Fachunterricht), welches Unterrichtsentwicklungsprojekte von Studierenden auch in zeitlich engen Seminarsettings ermöglicht. Die Erfahrungen aus dem Projekt zeigen, dass SELLF durch die Vernetzung von praktischen Fragestellungen mit theoriebasierten Konzepten zur Vertiefung von fremdsprachendidaktischen Kompetenzen beitragen kann. Zusätzlich werden die Studierenden durch das Erleben der Wirksamkeit ihres eigenen professionellen Handelns für Kernaspekte von Unterrichtsentwicklung sensibilisiert. Der Erfolg von SELLF-Projekten ist jedoch an Bedingungen geknüpft, die im Beitrag diskutiert werden.
Outcomes of Synchronization and Timed Insemination Coupled with Retained Ownership in a Commercial Beef Cattle Operation
Creators: name: Whittier, W. Dee
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: GnRH-based estrous synchronization programs have allowed for outstanding success in getting cows pregnant with timed insemination (TAI). This technology allows pregnancy rates approximating those of natural service to a single insemination. The system minimizes the requirement for estrus detection with its attendant error rates and high demand for labor. The overall method allows producers to select semen from superior sires with known progeny performance to meet the outcomes that are most economical for their operations. These outcomes include traits that provide for desirable parturition outcomes, high rates of growth and feed efficiency, and the production of carcasses that are sold for a premium because they receive desirable quality and yield grades. Retained ownership beef cattle production schemes are different from traditional beef cattle management approaches wherein calves change ownership from the cow/calf operation to the growing phase and finally to the finishing or feedlot phase. Retained ownership through the feedlot and then marketing finished cattle through a value-based program allows the cow/calf producer to be compensated for the actual value of the beef produced. Because most calf marketing schemes tend to value cattle based on industry averages, there is the potential to augment income through retained ownership if cattle have characteristics that result in performance and end-product that is superior to industry average.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Five glycosylated phenolic derivatives from the bark of Ilex rotunda Thunb. and their anti-inflammatory activities
Creators: name: Peng, Shou
name: Chen, Tong
name: Wang, Ge
name: Li, Chen-yue
name: Liu, Wen-jing
name: Wang, Wen-qiong
name: Xuan, Li-jiang
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Five new glycosylated phenolic derivatives, rotundosides A-E (1-5), and three known glycosides (6-8) were isolated from the 95% alcohol extract of the bark of Ilex rotunda. Their structures were elucidated by extensive spectroscopic analysis and comparison with the literature data. All new compounds possessed a [5-O-(E)-caffeoyl]-β-D-apiofuranosyl-(1→6)-β-D-glucopyranosyl group. The anti-inflammatory properties of all isolated compounds were evaluated using a modified nitric oxide (NO) production in lipopolysaccharide (LPS)-induced leukemia cells in mouse macrophage (RAW264.7) method. Compound 8, dracunculifoside H, showed significant anti-inflammatory activity in vitro.
Fetal Protection Against Continuous Exposure To Bovine Viral Diarrhea Virus Following Administration of A Vaccine Containing an Inactivated BVDV Fraction
Creators: name: Grooms, Daniel L.
name: Bolin, Steven R.
name: Coe, Paul H.
name: Borges, Rafael
name: Coutu, Christopher E.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Bovine viral diarrhea virus (BVDV) is a major viral pathogen of cattle, leading to substantial economic losses. A major source of loss is attributed to fetal infection with subsequent fetal pathology. The major source of virus transmission is cattle that are immunotolerant and persistently infected with BVDV. The objective of this study was to determine if a commercially available killed BVDV vaccine (CattleMasterR® Gold TM FP™ L5, Pfizer Animal Health) could protect cattle against viremia and fetal infection during continuous exposure to cattle persistently infected with the BVDV. This type of model may more closely represent natural challenge, including continuous exposure to multiple virus strains.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
BYD Type I and Type II SN Titer Response in Weaning Age Beef Calves Following the Administration, in Various Combinations, of Two MLV Vaccines Containing Different BYD Type 1 and Type 2 Strains
Creators: name: Jones, C. A.
name: Goehl, D. R.
name: Loughin, M.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Many preconditioning and feedlot vaccination protocols require two doses of BVD vaccine. Typically the same vaccine and same strains of BVD are used for each dose. Following vaccination, the immune response will be strongest against the strains of BVD virus in the vaccine; however, the immunity developed must also protect against exposure to heterologous strains in the field. Due to antigenic diversity in BVD virus, it is important to stimulate immunity against as wide array of viruses as possible. Theoretically, using combinations of different vaccines containing different strains of BVD will expose the immune system to a wider range of BVD virus. Whether this results in an improved immune response or broader protection against field strains of BVD remains to be proven. The objective of this study was to determine if vaccination with different combinations of two modified live virus vaccines, containing different strains of BVD Type 1 and 2, would improve serum neutralization (SN) titer response and weight gain.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Supplementary document for Scalable photonic integrated circuits for programmable control of atomic systems - 6596137.pdf
Creators: name: Menssen, Adrian
name: Hermans, Artur
name: Christen, Ian
name: Propson, Thomas
name: Li, Chao
name: Leenheer, Andrew
name: Zimmermann, Matthew
name: Dong, Mark
name: Larocque, Hugo
name: Raniwala, Hamza
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Supplement
title: Bank Stabilization at 325 Kings Mountain Road Woodside
title: Endangered Act Section 7(a)(2) Biological Opinion for the 325 Kings Mountain Road Bank Stabilization Project within the Town of Woodside, San Mateo County, California (Corps File No. 2016-00264S)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2017

description: ESA Section 7 Consultation ; WCRO-2017-01433
Scale-Up of the agitator speed based on computational fluid dynamics
Creators: name: Zogg, Andreas
name: Maier, Christian David
Publisher: name: Hochschule für Life Sciences FHNW
Year: 2021
Subjects: computational fluid dynamics
CFD
Agitated Vessel
Rührkessel
Mixing

description: Siegfried in Zofingen is currently working on a hydrogenation reaction. To mimic the production condition for the production, the reaction is carried out on a scale-down reactor laboratory scale (approx. 1 liter). One important process parameter that should be similar during the experiments of the scale-down reactor compared to the later production scale reactor is the mixing behaviour of the agitator. The goal of this work is to find a concept for the appropriate scale-down of the agitator speed based on computational fluid dynamics. This concept shall be compared to conventional scale up methods. To validate this concept different experiment with water and glycerol, as well with and without baffles, were carried out in a 5-litre scale reactor. For the simulation without baffles, the size of the vortex has been compared to the real experiment as well as conventional calculation. In general, the simulation predicted only a vortex 63.6 % of the measured size. In further experiments with suspending of catalyst particles, simulation with baffles were validated with catalyst particle behaviour. The particle behaviour in the experiments could not be measured accurately due to the small size of the particles and the insufficient camera quality. The simulation with particles had a critical error where particles got stuck on the wall which made the results unusable for particle movement prediction. Even with the simulation working correctly, it would not be beneficial for this project, due to the large amount of particles and the simplification done for the simulation. A second method was uses, where the mean velocity of cells in the steady state were compared to each other. Out of 3 different agitator speeds, the agitator speed calculated with keeping P/V constant (571 rpm) was most similar to the agitator speed of the reactor MZA1 (120 rpm). Due to the low sample size this only supports the result but does not confirm it. As a consequence, the results of this thesis give an indication for a possible solution to the stirring behaviour but conventional ways of finding the agitator speed are still necessary. It can be used as steppingstone, but it is still required to refine these simulations. Despite the dissatisfying result with the catalyst particles it could be shown that scale down of agitator speed can still be supported by the mean of computational fluid dynamics
title: Point Hudson Breakwater Replacement REINI 2016-4573
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the Point Hudson Breakwater Replacement.
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2022

description: ESA Section 7 Consultation ; WCRO-2021-00301
The effect of methyl jasmonate and light irradiation treatments on the stilbenoid biosynthetic pathway in Vitis vinifera cell suspension cultures
Creators: name: Andi, Seyed Ali
name: Gholami, Mansour
name: Ford, Christopher M
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Grape stilbenes are a well-known family of plant polyphenolics that have been confirmed to have many biological activities in relation to health benefits. In the present study, we investigated the effect of methyl jasmonate (MeJA) elicitor at four different concentrations (25, 50, 100 and 200 μM) in combination or not with high-level light irradiation (10,000 LUX) on a cell line obtained from the pulp of Vitis vinifera cv. Shahani. Our results showed that the stilbene synthesis pathway is inhibited by high-light conditions. A concentration of 50 μM MeJA was optimum for efficient production and high accumulation of total phenolics and total flavonoids as well as total stilbenoids. Furthermore, we showed that there is a significant negative correlation between the production of these metabolites and cell growth. These data provide valuable information for the future scale-up of cell cultures for the production of these very high value compounds in bioreactor system.
title: Caltrans - Fish Creek Fish Passage Project 2022
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson–Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for Caltrans’ Fish Creek Fish Passage Project on State Route 254 in Humboldt County, California
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2022

description: ESA Section 7 Consultation ; WCRO-2022-00165
Parameters of Ear Notch Samples for BVDV Testing
Creators: name: Ridpath, J. F.
name: Hessman, B. E.
name: Neill, J. D.
name: Fulton, R. W.
name: Step, D. L.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Infection with bovine viral diarrhea viruses (BVDV) is a major source of economic loss for the US cattle industry. Houe (2003) estimates that losses in areas where BVD is endemic range between $10 to 40 million per million calvings. Results of serology surveys in the US suggests that our losses are in the upper end of this range (Houe et al, 1995a; Houe et al, 1995b; Paisley et al, 1996). In 2004, 37.6 million calves were born in the US; thus, US losses by this estimate would be between $376 million to 1.5 billion for 2004. The 2005 calf crop was ~37.8 million, making the 2005 estimate very similar to that of 2004. While BVDV infections are well recognized as reproductive pathogens among dairy producers, producers are less aware that BVDV infections are also associated with increased respiratory disease, increased severity of secondary infections and decreased milk production. Persistently infected (PI) animals are the major vectors for spreading BVDV within and among herds. Based on studies of dairies of 100 cows or more, Joly et al (2005) estimated that the presence of one PI animal in a herd resulted in a loss of $1.93/cwt of milk sold. Studies estimate that 10-15% of US herds have at least one PI animal (Houe et al, 1995c; Wittum et al, 2001). In 2004, US dairies produced 170,805 million lb (77,638 kg) of milk. If 10% to 15% of dairy herds have at least one PI animal, then the cost to milk production is between $330 to 494 million per year. Control efforts in the US are geared towards identifying and eliminating Pis. Several tests based on detection of either antigen or viral RNA in blood, serum, bulk milk or skin biopsies are currently in use (Cornish et al, 2005; Fulton et al, 2006). Ear notch samples have become the tissue of choice for screening for PI animals because 1) they are easy to collect; 2) equipment requirements are minimal; 3) they are not affected by presence of passive antibodies; and 4) they can be used as the sample for a wide variety of tests including immunohistochemistry, real-time polymerase chain reaction and antigen-capture ELISA. While ear notches have become one of the samples of choice, there is little information available regarding sample size requirements and stability. Further, while pooling of ear notch samples has been proposed for reducing the cost of surveillance programs (Kennedy et al, 2006), the viral load available for detection from ear notch samples is largely undetermined. The purpose of this study was to establish working parameters for sample size, viral detection limit and sample storage conditions for real-time PCR and antigen-capture ELISA.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Estimations of Milk and Meat Withdrawal Times of Ketamine and Lidocaine in Adult Holstein Cows
Creators: name: Sellers, Glen
name: Lin, Hui-Chu
name: Riddell, M. Gatz
name: Ravis, William
name: Duran, Sue Hudson
name: Lin, Yuh-Jing
name: Given, M. Daniel
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Ketamine is a dissociative anesthetic commonly used for short-term and induction of anesthesia in bovine species. Ketamine has recently become popular for use as a constant-rate infusion for continuous pain relief. Lidocaine, a local anesthetic, is frequently used for local infiltration and epidural nerve blocks. Two of the most common local blocks in adult cattle are the inverted-L local infiltration and caudal epidural nerve blocks. These blocks are utilized for numerous standing surgical procedures such as cesarean sections, obstetric manipulations, correction of a displaced abomasum and perineal surgery. These animals may occasionally be sent for slaughter following a surgical procedure, and the Food and Drug Administration (FDA) has a zero-tolerance policy for drug residues in meat and milk. There is limited information and no published data on meat and milk withdrawal times for ketamine anesthesia or lidocaine administration via these two different techniques. The objectives of this study were to investigate the pharmacokinetics of ketamine following administration of a single intravenous dose and lidocaine administered via inverted-Land caudal epidural nerve blocks, and to establish the withdrawal times for meat and milk of these two anesthetics in mature Holstein cows.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Role of Vaccination in the Control of Johne's Disease in 3 Wisconsin Dairy Herds
Creators: name: Patton, Elisabeth
name: Fish, Richard
name: Engrav, Jeffery
name: Bohn, Jeffery
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: We set out to evaluate differences between vaccinated and non-vaccinated calves reared under the same conditions. Three larger Wisconsin dairy herds (300-800 head/herd) agreed to participate in the study. Every other heifer calf was vaccinated against JD until two cohorts, vaccinated and non-vaccinated, were established for each herd. Infection prevalence, clinical disease rate and longevity in the herd will be evaluated in the study.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
title: NPDES Permit for Net Pen Facilities
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the NPDES General Permit for Tribal Enhancement and Federal Research Marine Net Pen Facilities Within Puget Sound, NPDES Permit No. WAG132000.
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2022

description: ESA Section 7 Consultation ; WCRO-2021-03087
The Efficacy of Meloxicam as an Adjunct Therapy in the Treatment of Neonatal Calf Diarrhea Complex
Creators: name: Todd, C. G.
name: McKnight, D. R.
name: Millman, S. T.
name: Duffield, T. F.
name: Leslie, K. E.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Neonatal calf diarrhea complex has a significant impact on the dairy industry. The National Animal Health Monitoring System reports that diarrhea accounts for greater than 60% of pre-weaned calf deaths. A recent field study in Europe has identified beneficial effects of Meloxicam therapy in calves with diarrhea. This controlled trial examined the efficacy of Meloxicam administration in combination with oral electrolyte and antibiotic therapy for the treatment of calf diarrhea. Compared to control animals, the Meloxicam-treated calves experienced significant improvements in clinical parameters, such as hydration status, fecal consistency, rectal temperature and signs of visceral pain. Overall, calfrecovery from the episode of diarrhea was improved for calves receiving Meloxicam therapy, compared to placebo-treated calves. The objective of the current study was to examine the effects of Meloxicam administration on calf health, behavior and performance in calves with neonatal calf diarrhea complex in Ontario.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Effect of Johne's Disease Vaccination on Reducing Contamination of the Dairy Farm Environment
Creators: name: Cumpton, A. E.
name: Wells, S. J.
name: Patton, E. A.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: The results in this study can assist veterinarians and herd owners in decision-making regarding use of JD vaccine as an addition to other management practices to reduce transmission and improve control of JD.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
title: Miner Slough Bridge Replacement Project Reinitiation 2021
title: Endangered Species Act Section 7(a)(2) Biological Opinion and Magnuson–Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the Miner Slough Bridge Replacement Project Reinitiation 2021
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2022

description: ESA Section 7 Consultation ; WCRO-2021-02625
Appendix S1 from Phylogenomic analyses of more than 4000 nuclear loci resolve the origin of snakes among lizard families
Creators: name: Streicher, Jeffrey W.
name: Wiens, John J.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60301 Animal Systematics and Taxonomy
subject: FOS: Biological sciences
subject: 60310 Plant Systematics and Taxonomy

description: Detailed methods used for sequencing ultraconserved elements from squamate reptiles.
title: Salmon Whitewater Park and City of Salmon Waterline and Bank Stabilization Actions
title: Endangered Species Act Section 7 Formal Consultation and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Consultation for the Salmon Whitewater Park and City of Salmon Waterline and Bank Stabilization Actions, Middle Salmon-Panther, HUC 17060203, Lemhi County, Idaho (Three Projects)
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2022

description: ESA Section 7 Consultation ; WCRO-2021-03436
Optimierung des Ingenieurbauteams der ALLPLAN Schweiz AG
Creators: name: Fink, Urs
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2018
Subjects: BIM

description: Um herauszufinden wo Optimierungspotential vorhanden ist, werden die Punkte durch eine IST-Analyse definiert. Es wurden die letzten 3 Jahre, in den Bereichen Hotline, Schulung und Umsatzzahlen auswerten um den Grundstein für die Optimierung zulegen. Den Optimierungsprozess wurden vom VDC- Schema übernommen.
title: ADCO, Premier cartulaire de Saint-Étienne de Dijon (XIIe siècle), Cart. 21 (G 125), 71 folios, f. 00070
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Premier cartulaire de Saint-Étienne de Dijon (XIIe siècle), Archives départementales de la Côte-d'Or, Cart. 21 (G 125), 71 folios, f. 00070, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Premier cartulaire de Saint-Étienne de Dijon (XIIe siècle), Archives départementales de la Côte-d'Or, Cart. 21 (G 125), 71 folios, f. 00070, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: http://www.wikidata.org/entity/Q15945019
description: Provenance: abbaye Saint-Étienne de Dijon
An Evaluation of the Efficacy of On-farm Pasteurization of Waste Milk in Seven Western New York Dairies
Creators: name: Capel, Michael
name: Wentworth, Hillary
name: Crosier, Brooke
name: Welch, Gerald
name: Schukken, Ynte
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Whole milk has nutritional and economic benefits over milk replacer as a feed source for calves. Waste milk-non-saleable milk from treated cattle-represents the most affordable source of whole milk on the dairy. Despite its benefits, whole milk contains many pathogens and poses a disease risk to calves. Pasteurization has emerged as a valuable and cost-effective method for reducing the number of pathogenic bacteria present in waste milk on farms, and studies have shown numerous health and economic benefits through feeding pasteurized waste milk over un-pasteurized waste milk. There remains a need for identifying how effective pasteurizers are when operating under on-farm conditions. The objective of this study was to evaluate bacterial load in waste milk before and after on-farm pasteurization.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Angewandt. - Forschungsprojekte und ihr praktischer Nutzen
Creators: name: Schwander, Markus
Publisher: name: editionqubus
Year: 2018
Subjects: subject: Kunstpädagogik
subject: Kunst
subject: Bildnerisches Gestalten
subject: Raumwahrnehmung
subject: 3D-Druck
subject: Künstlerische Forschung
subject: 700 - Künste, Bildende Kunst allgemein
subject: S - Schulbücher
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Für die Publikation HEFT des Verbandes der Lehrerinnen und Lehrer für Bildnerische Gestaltung Schweiz (LBG) beschreibt Markus Schwander, wie am Institut Lehrerufe Gestaltung und Kunst HGK FHNW aus Forschungsprojekten konkrete Hilfestellungen für Lehrpersonen entstehen. Vorgestellt werden zwei Publikationen, für welche auf unterschiedliche Weise Aufgaben für den Unterricht entwickelt wurden. In Zusammenhang mit dem Forschungsprojekt „Grenzgang“ verfasste Simone Etter im „WALKBOOK“ 13 promenadologische Raumexperimente, in Zusammenhang mit der Strategischen Initiative " der FHNW entstand das Lehrmittel „formen. 3D-Druck lernen und lehren“ von Stefanie Mauroux, Falk Scheidig und Markus Schwander mit 7 Aufgaben zur Förderung des Zuganges zum 3D-Drucker.
Effects of Two-Week Oral IGG Supplementation in Pre-Weaned Calves on Morbidity, Mortality, and Weight Gain
Creators: name: Moore, D. A.
name: Berge, A. C. B.
name: Acre, S.
name: Sischo, W. M.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Because of growing concern over antimicrobial resistance, alternatives to antimicrobial use in animal production are needed. One potential way to reduce treatment is to provide improved caloric and IgG supplementation in the neonatal period. The objectives of this study were to determine the effect of 14 days of an oral dehydrated colostrum supplement added to milk-replacer for pre-weaned calves on calf morbidity and treatments, mortality, feed intake and weight gain.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Use of a Fecal PCR Assay on Environmental Samples for Detection of Dairy Cattle Herds Infected with Johne's Disease
Creators: name: Cernicchiaro, N.
name: Wells, S. J.
name: Muñoz-Zanzi, C.
name: Gaulke, J.
name: Wees, C.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: The goal of this study was to evaluate the application of fecal PCR assay for diagnosis of Mycobacterium avium subspecies paratuberculosis in environmental samples and to determine its sensitivity for detection of dairy cattle herds infected with JD
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
title: Morris Riprap extension
title: Endangered Species Act - Section 7 Consultation Biological Opinion Shoreline Stabilization, Bokeelia, Lee County, Florida
Creators: name: United States. National Marine Fisheries Service. Southeast Region
Publisher: name: United States. National Marine Fisheries Service. Southeast Region
Year: 2022

description: ESA Section 7 Consultation ; SERO-2021-01605
Factors Associated with ELISA S/P Ratio Scores for Paratuberculosis in an Angus-Brahman Multibreed Herd of Beef Cattle
Creators: name: Elzo, M. A.
name: Rae, D. O.
name: Lanhart, S. E.
name: Wasdin, J. G.
name: Dixon, W. P.
name: Jones, J. L.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Dam and calf genetic and environmental factors were evaluated for their association with enzyme-linked immunosorbent assay (ELISA) s/p ratio scores for paratuberculosis in a multibreed beef cattle population.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006