cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Design and evaluation of an Open Web Platform cartography lab curriculum
Creators: name: Sack, Carl M.
name: Roth, Robert E.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Recent shifts in web map technology away from proprietary software and toward development on the Open Web Platform have increased the number and complexity of technical skills needed to do cartography on the Web. Web-based cartography curricula likewise must be adapted to prepare geography, cartography, and GIS students with the skills needed to make use of open source technology. This paper describes the design and evaluation of a novel curriculum for the laboratory component of a web mapping course offered by a university geography department. We drew from constructivist educational theory to create a scaffolded and spiralled lab curriculum that builds on prior understanding and progressively increases student independence and confidence. We evaluated the success of the new curriculum through an instructor log, student feedback on assignments, and an exit survey. The evaluation revealed significant growth in student abilities and confidence in the use of Open Web Platform-based mapping tools as a result of the curriculum scaffolding. This research provides a methodology for designing and evaluating curriculum around highly technical skills that are increasingly in demand in research, education, and industry careers.
Nordic Walking for People with Cardiovascular Disease: A Systematic Review
Creators: name: Cugusi, Lucia
Publisher: name: figshare
Year: 2016
Subjects: subject: 110321 Rehabilitation and Therapy (excl. Physiotherapy)
subject: FOS: Clinical medicine

description: It is well established that exercise is the cornerstone of rehabilitation programs for people with cardiovascular disease (CVD). Although traditional and standardized forms of exercise have significant cardiovascular (CV) benefits, emerging and non-conventional physical activities such as Nordic walking (NW), may offer additional/incremental health benefits.The aim of this systematic review is to appraise research evidence on the effects of NW on the management of people with CVD. Procedures: A comprehensive literature search of clinical databases (Pubmed, Medline, Scopus and Web of Science) will be conduct to identify any relevant English language study published from inception to 2016 and reference lists were hand searched. To be included in the review, the articles needed to involve: (a) People with CVD and (b) Analysis of acute and long-term effects of NW.Results and conclusion will be product at the end of analysis.
Salt and obesity: a systematic review and meta-analysis of observational studies
Creators: name: Seyedeh Parisa Moosavian
name: Fahimeh Haghighatdoost
name: Surkan, Pamela J.
name: Azadbakht, Leila
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Background: Existing research has investigated the association between sodium intake and obesity. We aim to conduct a systematic review and meta-analysis of reported evidence regarding the association between sodium intake and obesity. Methods: Multiple electronic databases (PubMed, Scopus, and Google Scholar) were searched for observational studies published until August 2016. A systematic literature review identified 11 cohort and 21 cross-sectional studies. Result: Among the 32 studies identified in the systematic literature search, only 18 cross-sectional reports had sufficient data to be included in the meta-analysis. Higher sodium consumption was associated with greater BMI (weighed mean difference (WMD) = 1.24 kg/m2, 95%CI: 0.80, 1.67; I2 = 98.4%; p p Conclusion: The present meta-analysis suggests that sodium consumption was associated with greater BMI and WC.
Romance gracioso y entretenido en que se refiere el testamento que hizo el maldito Judas: Digital edition
Creators: name: Miguel, Betti
name: Leblanc Elina
Publisher: name: Zenodo
Year: 2021
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2022), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Ex vivo analyses of formulated bio-elicitors from a phytopathogen in the improvement of innate immunity in host
Creators: name: Nilanjan Chakraborty
name: Krishnendu Acharya
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Three different bio-elicitors viz. BE 1, BE 2 and BE 3 were formulated from Fusarium oxysporum f. sp. lycopersici. All three elicitors were screened for defence regulating capacity in an ex vivo system where Lycopersicum esculentum was used as a model host plant. Application of bio-elicitors on detached leaves showed varied degrees of defence induction and antioxidative enzymes and total phenol accumulation after 24 h incubation. Among all, BE 3 (2%) was found to be the most effective. Furthermore, production of nitric oxide (NO) was measured in treated leaves, and concurrently, the extent of oxidative damage was evaluated by measuring reactive oxygen species (ROS), malondialdehyde (MDA), proline and total chlorophyll content. All bio-elicitors except BE 3, which was effective at concentrations as low as 2%, showed enhanced production of MDA and proline and reduction in total chlorophyll at higher concentrations. These results suggest that among three elicitors tested, BE 3 (2%) can be used as a potential bio-elicitor in organic tomato farming.
Romance gracioso y entretenido en que se refiere el testamento que hizo el maldito Judas: Digital edition
Creators: name: Miguel, Betti
name: Leblanc Elina
Publisher: name: Zenodo
Year: 2022
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2022), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Romance gracioso y entretenido en que se refiere el testamento que hizo el maldito Judas: Digital edition
Creators: name: Betti Miguel
name: Leblanc Elina
Publisher: name: Zenodo
Year: 2024
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Nordic Walking for the Management of People with Parkinson’s Disease: A Systematic Review of Randomized Controlled Trials
Creators: name: Cugusi, Lucia
Publisher: name: figshare
Year: 2016
Subjects: subject: 110321 Rehabilitation and Therapy (excl. Physiotherapy)
subject: FOS: Clinical medicine

description: It is well known that physical exercise is the main therapeutic element of neurorehabilitation programs for people with Parkinson's disease. As traditional and common forms of exercise can guarantee significant health benefits, the emergence of non-conventional physical activities, such as Nordic walking (NW), may add positive global effects. The aim of this systematic review is to appraise and analyze research on the effects of NW in the management of people with Parkinson’s disease. A comprehensive literature search of clinical databases (PubMed, Medline, Scopus and Web of Science) will be conduct to identify any relevant randomized controlled trials (RCTs), published in English from inception to 2016, and the reference lists were hand searched. To be included in the review, articles needed to involve: (i) people with Parkinson’s disease; (ii) an analysis of the main outcomes arising from a NW program. The methodological quality of each study will be assessed by the Physiotherapy Evidence Database scale (PEDro).Results and conclusions will be provided at the end of analysis.
Non-halogenated new sesquiterpenes from Bornean Laurencia snackeyi
Creators: name: Kamada, Takashi
name: Vairappan, Charles Santhanaraju
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: Two new non-halogenated sesquiterpenes, snakeol (1) and snakediol (2) were isolated together with 9 known sesquiterpenes such as (R,Z)-33-dimethyl-5-methylene-4-(3-methylpenta-24-dien-1-yl)cyclohex-1-ene (3), palisol (4), pacifigorgiol (5), palisadin D (6), palisadin A (7), palisadin B (8), 5-acetoxypalisadin B (9), debromolaurinterol (10) and α-bromocuparane (11) from the red algae Laurencia snackeyi. The structures of two new metabolites were determined from their spectroscopic data (IR, 1D and 2D NMR and MS). Compounds 1, 2, 10 and 11 showed strong antibacterial activity against selected human clinical bacterial pathogens.
Table S1 from Long-distance autumn migration across the Sahara by painted lady butterflies: exploiting resource pulses in the tropical savannah
Creators: name: Constantí Stefanescu
name: Soto, David X.
name: Talavera, Gerard
name: Vila, Roger
name: Hobson, Keith A.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: Supplementary material from "Long-distance autumn migration across the Sahara by painted lady butterflies: exploiting resource pulses in the tropical savannah"
The Reverse Effect of Reviewers’ Sentiment Tendency: The Role of Readers’ Empathy and Trust
Creators: name: Li, Pengyu
name: Shao, Jingbo
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Neuroscience
Biotechnology
Science Policy
Mental Health

description: Streamers have become a crucial component of consumers’ live shopping experience. Reviewers will transfer their emotions about the streamer to the product-after review. We innovatively verified the reverse effect of reviewers’ sentiment tendency toward streamer on the product sustained sale in the streamer’s live streaming. Results from a field data set and three lab experiments show that reviewers’ positive sentiment tendency toward the streamer has a negative effect on the readers’ purchase intention when the streamer resale this product in his live streaming. While reviewers’ negative sentiment tendency toward the streamer can enhance readers’ purchase intention to the product resold in the streamer’s live streaming. These effects are separately mediated by readers’ trust in the review and their empathy to the streamer. And the two mediators are moderated by the streamer’s expertise. Our findings expand the literatures about reviews’ emotions and suggest implications for streamers, retailers, and review platforms faced with the task of managing live-shopping reviews.
EEG, EOG, Likert Scale, and Interview Approaches for Assessing Stressful Hazard Perception Scenarios
Creators: name: Rui, Zhepeng
name: Li, Yahong
name: Dong, Zhanxun
name: Hao, Lingyu
name: Chen, Bingliang
name: Chang, Fangyuan
name: Gu, Zhenyu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: This study aimed to detect stressful hazard perception scenarios subjectively and objectively when using intelligent driving systems. We used electrooculography (EOG), electroencephalography (EEG), subjective ratings, and interviews to identify potential stressful hazard perceptions and record improvements in an intelligent navigation-guided pilot (NGP) system. Moreover, we analyzed electrophysiological data. Our study contributes to the use of engagement, concentration, and phase locking value connectivity based on EEG to support previous research methodologies using beta power, pupil size, fixation ratio, fixation duration, and subjective evaluations for investigating hazard perception. Our analyses showed that stressful hazard perception scenarios occurred mainly when encountering broken and solid lines, frequent lane changes, cars approaching suddenly, several cars driving in parallel, and the decision to change lanes but immediately pulling back upon using the NPG system. Our findings shed light on obtaining accurate results based on subjective and objective evaluations for developing intelligent driving systems.
Stayers and Leavers report
Creators: name: Thompson, Elizabeth
name: Williams, Clay
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024
Subjects: Research
Journalism
Local mass media
Labor
Reporters and reporting
Labor unions

description:
The Stayers and Leavers report from the Center for Innovation and Sustainability in Local Media (CISLM) at UNC-Chapel Hill examines the career trajectories of more than 600 current and former local journalists across the United States. Fielded in early 2024, the survey identifies key factors that influence journalists to remain in or exit the profession, including salary levels, work-life balance, burnout, union representation, and future confidence in the industry. Findings reveal that journalists are more likely to stay in local news if they work fewer hours, are part of a unionized newsroom, and perceive journalism as a calling. Conversely, low pay, mental health strain, long hours, and lack of advancement opportunities drive attrition—especially among women, journalists of color, and LGBTQ+ individuals. With nearly 80% of respondents reporting burnout and half experiencing online harassment, the report underscores the urgent need for systemic change to support a sustainable future for local journalism. Recommendations include boosting wages, reducing overwork, and fostering workplace cultures that prioritize retention and well-being.
Evaluation of antioxidant activity, total phenolics, total flavonoids and LC–MS/MS characterisation of phenolic constituents in Stachys lavandulifolia
Creators: name: Soroush Rahimi Khoigani
name: Rajaei, Ahmad
name: Goli, Sayed Amir Hossein
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: The aim of this study was to evaluate phenolics profile and antioxidant activity of Stachys lavandulifolia. Total phenolics (TP), total flavonoids (TF), DPPH• assay (IC50), ferric ion reducing antioxidant power (FRAP) and total antioxidant capacity (TAC) of the methanolic extract were measured. The content of TP, TF, IC50, FRAP and TAC, were obtained as 16.59 gallic acid equiv./g dry matter (DM), 4.48 mg quercetin equiv./g DM, 2.07 (μg/mL), 0.014 (absorbance/mg phenolic) and 14.61 (mg BHT equiv./g DM), respectively. The results showed that S. lavandulifolia, compared to other species of Stachys, had moderate TP content with desirable antioxidant activity. Subsequently, 59 various phenolic compounds were identified and confirmed in the methanolic extract of S. lavandulifolia using high mass accuracy by MS2 experiments. The compounds consisted of 6 hydroxybenzoic acids and hydroxybenzoic aldehydes, 9 hydroxycinnamic acids, 1 coumarin, 32 flavonoids, 3 lignans, 2 stilbenes, 3 tannins and 3 other phenolics.
Stone-Age Scientific & Astronomical Instruments: Newgrange & Portuguese Burial Tombs Compared
Creators: name: Doble, Rick
Publisher: name: figshare
Year: 2016
Subjects: subject: 20102 Astronomical and Space Instrumentation
subject: FOS: Physical sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: Stellar Astronomy
subject: History

description: A recent study proposed that the long passageways of Portuguese burial tombs were essentially the world's first telescopes. The long passageway at the passage tomb at Newgrange Ireland that is aligned with the winter solstice sunrise can also be considered another kind of Neolithic astronomical instrument. This paper compares the two designs and the similarity between them.
Evaluating Digitalized Visualization Interfaces: Integrating Visual Design Elements and Analytic Hierarchy Process
Creators: name: Liu, Zhiping
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Space Science
Medicine
Information Systems not elsewhere classified
Science Policy
Plasma Physics

description: This study addresses a fundamental scientific issue in digital interface design: the quantification of visual elements to enhance interface efficiency and user satisfaction. We propose an innovative framework combining the Analytic Hierarchy Process with visual design principles to quantitatively define and optimize design elements. The core of our research is a quantitative assessment method for interface design, aiming to advance the scientific understanding and development of digital user experience. We anticipate this approach will reveal the interplay between functionality, aesthetics, and emotion, guiding the creation of more appealing and efficient interfaces. Our findings clarify the scientific issue of integrating aesthetics with functionality in digital interface design, offering a systematic solution. This not only aids designers and researchers in understanding and evaluating the impact of interface design but also lays a solid theoretical and methodological foundation for future studies, encouraging a deeper scientific comprehension of the integration of aesthetics and functionality in interface design and exploring its application in crafting more effective and enjoyable user experiences.
9th UK Mesenchymal Stem Cell Meeting.docx
Creators: name: Anderson, Hilary
name: Donnelly, Hannah
Publisher: name: figshare
Year: 2016
Subjects: subject: Biotechnology
subject: 100703 Nanobiotechnology
subject: FOS: Nanotechnology
subject: Stem Cells
subject: 100404 Regenerative Medicine (incl. Stem Cells and Tissue Engineering)
subject: FOS: Medical biotechnology

description: The 9th UK mesenchymal stem cell meeting, was held at The University of Manchester, December 2015. Centre for Cell Engineering's Professor Matthew Dalby was one of the keynote talks and discussed materials for MSC growth and differentiation. Other keynote speakers included Professor Richard Oreffo and Professor Paul Sharpe who also spoke on the diverse field of MSC in vitro study.
title: Asymptotic Expansion of a Maier-Saupe Type Potential Near the Nematic-Isotropic Transition Point in liquid Crystals
Creators: name: ONeill, Ryan P.
name: Nguyen, Giangvuthanh
name: Xu, Xiang
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2024

description: In this paper we study a Maier-Saupe type bulk potential (Maier & Saupe, 1959) in the Landau-de Gennes free energy in the Q-tensor theory modeling nematic liquid crystal configurations. This potential was originally introduced in Katriel et al. (1986), which is considered as a natural enforcement of a physical constraint on the eigenvalues of symmetric, traceless Q-tensors. More specifically, we present a rigorous derivation of the asymptotic expansion of this singular potential near the nematic-isotropic transition point up to the 4-th order.
Sea ice generation code for 'Storylines of the 2018 Northern Hemisphere heat wave at pre-industrial and higher global warming levels': Python Code
Creators: name: Wehrli, Kathrin
Publisher: name: ETH Zurich
Year: 2020
Subjects: Sea ice
SST
anomaly mapping

description: This code for python accompanies the publication 'Storylines of the 2018 Northern Hemisphere heat wave at pre-industrial and higher global warming levels' in Earth System Dynamics. It contains the sea ice generation method developed for the publication and described in its section 2.5.
description: python
Supplementary Material for DG.O'25 Submission "Brazilian Federal Institutions as Intermediaries: Driving Digital Transformation Through Open Innovation"
Creators: name: Alves de Lima Júnior, Joel
name: Gama, Kiev
name: da Silva Correia Neto, Jorge
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 350705
subject: Innovation management
classificationCode: 350714
subject: Public sector organisation and management

description: This supplementary material contains the semi-structured interview guide and systematic literature review that were used in our research published in the 26th Annual International Conference on Digital Government Research (dg.o 2025).
title: Mothers and Daughters: A Study of Edith Wharton
Creators: name: Waller, Patricia K.
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1991

description: Whether due to her own mother's coldness, or to the fact that she herself did not have children, or to some other factor or combination of factors, Edith Wharton seemed unable to envision a warm, satisfying mother-daughter relationship. The mothers in her fiction are often detached and/or absent, and the daughters suffer from the faulty or nonexistent relationships with their mothers. The "motherless" daughters--Lily Bart, Mattie Silver, and Charity Royall--never achieve adulthood in any real sense. They lack autonomy and remain dependent on others. Other daughters--Nona Manford and Judith Wheater--must take over the parental role when their mothers fail to nurture them adequately. Only May Welland cares across as a nurturing mother who is genuinely concerned about the welfare of her children and who cares for them consistently. However, Wharton gave us only sketchy details about May as mother. Wharton's pessimistic view of life prevented her from portraying happiness in mother-daughter relationships in her fiction.
Klimawandel: PSC Discovery Workshop
Creators: name: Faller, Patrick
name: Schläpfer-Miller, Juanita
name: Schumacher, Ralph
name: Dahinden, Manuela
name: Buchmann, Nina
Publisher: name: ETH Zurich
Year: 2019

description: Die Lerneinheit «Klimawandel» besteht aus drei Teilen. Der erste und dritte Teil sind theoretische Lektionen, welche den zweiten praktischen Teil sinnvoll einbetten und die Relevanz des Themas verdeutlichen.
description: Lerneinheit, 1
Burrow ornamentation in the fiddler crab (Uca leptodactyla): female mate choice and male–male competition
Creators: name: R. De O. Rodrigues
name: T. M. Costa
name: R. E. Barreto
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Non-biological ornamentation is found in the nests and burrows of different kinds of animals. We evaluated here whether sand hoods constructed by male fiddler crabs (Uca leptodactyla) are one of the signals used by males to attract females during courtship. We observed females when they were walking among the males, and we quantified the proportion of females that visited male burrows with and without ornamentation and the choice to stay in a male’s burrow. Females visited more burrows with hoods than burrows without hoods, and they chose significantly more builder males. Male investment in ornamentation nevertheless decreased when the proportion of females increased in the area. Male investment was not correlated with the proportion of non-builder males nearby, but was positively correlated with overall density. The density sex ratio, however, was more male-biased in high-density than in low-density areas suggesting that even if building attracts females, the function could be related to male competition for mates.
Ausstellung des CreativeLabZ (2020)
Creators: name: Schläpfer-Miller, Juanita
name: Dahinden, Manuela
Publisher: name: ETH Zurich
Year: 2020

description: Im Februar 2020 fand die erste Ausstellung von CreativeLabZ im Museum für Digitale Kunst in Zürich statt. Von Elektroschockmeldern bis Wasserqualitätsmesser, die Vielzahl an tollen Ideen war überwältigend. Das CreativeLabZ ist ein Angebot für Jugendliche. Es baut auf Lebendigkeit und Begeisterung statt Leistungsdruck und Stress auf. Ein kreatives Lernumfeld unterstützt die Jugendlichen dabei, ihre Lebensfreude, Entdeckerlust und Gestaltungskraft zu erkunden. Gemeinsam mit Wissenschaftlerinnen, Künstlerinnen und Programmiererinnen entwickeln die Kinder und Jugendlichen eigene Roboter, Messgeräte und Kunstobjekte.  Anstatt einfachen Schritt-für-Schritt-Anleitungen zu folgen, werden die Kinder und Jugendlichen angeregt, aktiv zu testen und neue Lösungswege zu suchen. Der Prozess des Tüftelns (Tinkering) steht dabei im Mittelpunkt. Selbstkompetenzen wie kreatives Denken, Gestalten, nachhaltiges Handeln, Teambildung und Projektmanagement werden gestärkt. Fähigkeiten, die in der Zukunft immer wichtiger werden.
Potential influence of overpressurized gas on the induced seismicity in the St. Gallen deep geothermal project (Switzerland)
Creators: name: Zbinden, Dominik
name: Rinaldi, Antonio Pio
name: Diehl, Tobias
name: Wiemer, Stefan
Publisher: name: ETH Zurich
Year: 2019

description: In July 2013, the city of St. Gallen conducted a deep geothermal project that aimed to exploit energy for district heating and generating power. A few days after an injection test and two acid stimulations that caused only minor seismicity, a gas kick forced the operators to inject drilling mud to combat the kick. Subsequently, multiple earthquakes were induced on a fault several hundred meters away from the well, including a ML 3.5 event that was felt throughout the nearby population centers. Given the occurrence of a gas kick and a felt seismic sequence with low total injected fluid volumes (~ 1200 m3), the St. Gallen deep geothermal project represents a particularly interesting case study of induced seismicity. Here, we first present a conceptual model based on seismic, borehole and seismological data suggesting a hydraulic connection between the well and the fault. The overpressurized gas, which is assumed to be initially sealed by the fault, may have been released due to the stimulations before entering the well via the hydraulic connection. We test this hypothesis with a numerical model calibrated against the borehole pressure of the injection test. We successfully reproduce the gas kick and the temporal and spatial characteristics of the main seismicity sequence that followed the well control operation. The results indicate that the gas may have destabilized the fault during and after the injection operations and could have enhanced the resulting seismicity. This study may have important implications for future deep hydrothermal projects conducted in similar geological conditions.
description: Solid Earth Discussions
description: ISSN:1869-9537
title: Avant-propos_Traité d'ajustage et de mécanique
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Avant-propos
description: ID_PARA_00856
Revisiting microbe-metabolite interactions: doing better than random
Creators: name: Morton, James T.
name: McDonald, Daniel
name: Aksenov, Alexander A.
name: Nothias, Louis Felix
name: Foulds, James R.
name: Quinn, Robert A.
name: Badri, Michelle H.
name: Swenson, Tami L.
name: Van Goethem, Marc W.
name: Northen, Trent R.
name: Vázquez-Baeza, Yoshiki
name: Wang, Mingxun
name: Bokulich, Nicholas
name: Watters, Aaron
name: Song, Se Jin
name: Bonneau, Richard
name: Dorrestein, Pieter C.
name: Knight, Rob
Publisher: name: ETH Zurich
Year: 2019

description: Recently, Quinn and Erb et al [1] made the case that when used correctly, correlation and proportionality can outperform MMvec when identifying microbe-metabolite interactions. We revisit this comparison and show that the proposed correlation and proportionality are outperformed by MMvec on real data due to their inability to deal with sparsity commonly observed in microbiome and metabolome datasets.
description: bioRxiv
Defining the Pandemic at the State Level: Sequence-Based Epidemiology of the SARS-CoV-2 virus by the Arizona COVID-19 Genomics Union (ACGU)
Creators: name: Ladner, Jason T.
name: Larsen, Brendan B.
name: Bowers, Jolene R.
name: Hepp, Crystal M.
name: Bolyen, Evan
name: Folkerts, Megan
name: Sheridan, Krystal
name: Pfeiffer, Ashlyn
name: Yaglom, Hayley
name: Lemmer, Darrin
name: Sahl, Jason W.
name: Kaelin, Emily A.
name: Maqsood, Rabia
name: Bokulich, Nicholas
name: Quirk, Grace
name: Watts, Thomas D.
name: Komatsu, Kenneth
name: Waddell, Victor
name: Lim, Efrem S.
name: Caporaso, J. Gregory
name: Engelthaler, David M.
name: Worobey, Michael
name: Keim, Paul
Publisher: name: ETH Zurich
Year: 2020

description: In December of 2019, a novel coronavirus, SARS-CoV-2, emerged in the city of Wuhan, China causing severe morbidity and mortality. Since then, the virus has swept across the globe causing millions of confirmed infections and hundreds of thousands of deaths. To better understand the nature of the pandemic and the introduction and spread of the virus in Arizona, we sequenced viral genomes from clinical samples tested at the TGen North Clinical Laboratory, provided to us by the Arizona Department of Health Services, and at Arizona State University and the University of Arizona, collected as part of community surveillance projects. Phylogenetic analysis of 79 genomes we generated from across Arizona revealed a minimum of 9 distinct introductions throughout February and March. We show that >80% of our sequences descend from clades that were initially circulating widely in Europe but have since dominated the outbreak in the United States. In addition, we show that the first reported case of community transmission in Arizona descended from the Washington state outbreak that was discovered in late February. Notably, none of the observed transmission clusters are epidemiologically linked to the original travel-related cases in the state, suggesting successful early isolation and quarantine. Finally, we use molecular clock analyses to demonstrate a lack of identifiable, widespread cryptic transmission in Arizona prior to the middle of February 2020.
description: medRxiv
Soluble corn fiber reduces ovalbumin-induced sinonasal inflammation via the gut microbiota-airway axis
Creators: name: Jaramillo, Sierra A.
name: Borsom, Emily M.
name: Orsini, Gabrielle M.
name: Kask, Oliver
name: Lee, Keehoon
name: Hirsch, Allyson H.
name: Settles, Erik
name: Shi, Xiaojian
name: Gu, Haiwei
name: Koppisch, Andrew T.
name: Bokulich, Nicholas
name: Caporaso, J. Gregory
name: Cope, Emily K.
Publisher: name: ETH Zurich
Year: 2020

description: Asthma is a chronic airway inflammatory disease that affects approximately 300 million people worldwide, causing a substantial healthcare burden. Although there is a large degree of heterogeneity in the inflammatory response of asthmatics, a subset of patients are characterized by type-2 inflammation, which is in part mediated by TH2 cells in both the upper and lower airways. Asthma prevalence is increased in low-socioeconomic-status populations, where disparities in health behavior exist, including a shift toward a western diet characterized by low dietary fiber. Gut microbes metabolize fiber into short chain fatty acids that can reduce type-2 inflammation in peripheral organs, such as the airways. We hypothesized that soluble fiber can reduce ovalbumin (OVA)-induced upper airway inflammation in the context of the unified airway hypothesis, in mice maintained on ingredient-matched western (WD) and control diets (CD) through production of short chain fatty acids. Our results show that soluble fiber reduces IL-4 and IL-13 gene expression (p<0.05, Mann Whitney) in the sinonasal cavity of CD-fed mice, but this effect was lost in WD-fed mice. This loss of protection in WD-fed mice parallels compositional changes of the cecal and fecal microbiota. Mice fed a soluble fiber supplement while being maintained on a WD had altered microbial communities characterized by lower abundance of fiber fermentering bacteria. This work can be used to develop effective microbiome-based therapeutics as a low-cost method to reduce asthma morbidity.

IMPORTANCE Previous research has supported that western-style diets, typically high-fat and low-fiber, are associated with changes in the gut microbiome and increased inflammation. Western diets are accessible and prominent in low-socioeconomic-status populations, where asthma rates are highest; however, there has yet to be a low-cost asthma therapeutic. For the first time, we investigated whether supplementation with a physiologically relevant quantity of soluble corn fiber can reduce allergic airway inflammation. Our study supports that soluble corn fiber supplementation is associated with compositional shifts of the gut microbiota and reduced airway inflammation, promoting the use of fiber as a low-cost microbiome modifying therapy to reduce asthma-associated inflammation. However, soluble corn fiber in conjunction with a western diet resulted in an alternate gut microbiome composition and loss of protection against allergic airway inflammation. These findings further support the importance of the gut microbiota in host health.
description: bioRxiv
Supplementary Material for DG.O'25 Submission "Brazilian Federal Institutions as Intermediaries: Driving Digital Transformation Through Open Innovation"
Creators: name: User, Unknow
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 350705
subject: Innovation management
classificationCode: 350714
subject: Public sector organisation and management

description: This supplementary material contains the semi-structured interview guide and systematic literature review that were used in our research published in the 26th Annual International Conference on Digital Government Research (dg.o 2025).
Creative Camps: Verknüpfung von Kunst- und Wissenschaftsvermittlung
Creators: name: Schläpfer-Miller, Juanita
name: Dahinden, Manuela
Publisher: name: ETH Zurich
Year: 2020

description: Mit dem Projekt Creative Camps möchte das Zürich-Basel Plant Science Center Kindern im Alter von 8–14 Jahren das Erleben von Kunst und Wissenschaft ermöglichen. Der Einbezug verschiedener Formen der künstlerischen Gestaltung ermöglicht einen neuen, individuellen Zugang zu gesellschaftsrelevanten Themen aus der Pflanzenforschung. Gemeinsam erkunden wir, warum es Artenvielfalt braucht, wie Pflanzen mit Insekten kommunizieren, und welche Technologien uns helfen, die Umwelt zu schützen.
 
Der innovative Aspekt dieses Projekts ist die Art und Weise, wie Wissenschaftskommunikatorinnen mit Kunstpädagoginnen zusammenarbeiten, um wissenschaftliche Themen in einen künstlerischen Kontext zu setzen. Entstanden sind Workshopmodule, die Kunst- und Wissenschaftsvermittlung verknüpfen. Die Aktivitäten können ohne grossen Aufwand in ausserschulischen Lernorten – mit Gruppenleiterinnen in einem Ferienlager oder als schulische Projektwochen in der Natur – durchgeführt werden. Eine kurze Einführung erläutert die wissenschaftlichen Hintergründe und die Lernziele jeder Aktivität. Materiallisten und Schritt für Schritt-Anleitungen ermöglichen eine genaue Planung und die reibungslose Durchführung. Dennoch bleibt genug Raum für die Kinder und Jugendlichen zum Selbstausprobieren, Forschen und Tüfteln. Weiterführende Informationen stellen die Experimente in den Kontext aktueller Forschung.
description: ISBN:978-3-907234-04-4
Species-level microbial sequence classification is improved by source-environment information
Creators: name: Kaehler, Benjamin D.
name: Bokulich, Nicholas
name: McDonald, Daniel
name: Knight, Rob
name: Caporaso, J. Gregory
name: Huttley, Gavin A.
Publisher: name: ETH Zurich
Year: 2019

description: Popular naive Bayes taxonomic classifiers for amplicon sequences assume that all species in the reference database are equally likely to be observed. We demonstrate that classification accuracy degrades linearly with the degree to which that assumption is violated, and in practice it is always violated. By incorporating environment-specific taxonomic abundance information, we demonstrate that species-level resolution is attainable.
description: bioRxiv
Lack of evidence that ursodeoxycholic acids effects on the gut microbiome influence colorectal adenoma risk
Creators: name: Pearson, Talima
name: Caporaso, J. Gregory
name: Yellowhair, Monica
name: Bokulich, Nicholas
name: Roe, Denise J.
name: Wertheim, Betsy C.
name: Linhart, Mark
name: Martinez, Jessica A.
name: Bilagody, Cherae
name: Hornstra, Heidie
name: Alberts, David S.
name: Lance, Peter
name: Thompson, Patricia A.
Publisher: name: ETH Zurich
Year: 2017

description: Objective We previously reported that Ursodeoxycholic acid (UDCA), a therapeutic bile acid, reduces risk for advanced colorectal adenoma in men but not women. Interactions between the gut microbiome and fecal bile acid composition as a factor in colon cancer neoplasia have been postulated but evidence is limited to small cohorts and animal studies.

Design Using banked stool samples collected as part of a phase III randomized clinical trial of UDCA for the prevention of colorectal neoplasia, we compared change in the microbiome composition after 3 years intervention in a subset of participants randomized to 8–10 mg/kg of body weight UDCA (n=198) to placebo (n=203). UDCA effects on the microbiome, sex and adenoma outcome were investigated.

Results Study participants randomized to UDCA experienced compositional changes in their microbiome that were statistically more similar to other individuals in the UDCA arm than to those in the placebo arm. This change reflected an UDCA-associated shift in microbial community distance metrics (P <0.001), independent of sex, with no evidence of UDCA effect on microbial richness (P > 0.05). These UDCA-associated shifts in microbial community distance metrics from baseline to end-of-study were not associated with risk of any or advanced adenoma (all P> 0.05) in men or women.

Conclusion Despite a large sampling of randomized clinical trial participants, daily UDCA use only modestly influenced the relative abundance of microbial species in stool with no evidence for effects of UDCA on stool microbial community composition as a modifier of colorectal adenoma risk.
description: bioRxiv
Supplementary Methods from Mutation rate analysis via parent–progeny sequencing of the perennial peach I. A low rate in woody perennials and a higher mutagenicity in hybrids
Creators: name: Zhengqing Xie
name: Wang, Long
name: Lirong Wang
name: Zhiqiang Wang
name: Zhenhua Lu
name: Dacheng Tian
name: Sihai Yang
name: Hurst, Laurence D.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60408 Genomics

description: Mutation rates vary between species, between strains within species and between regions within a genome. What are the determinants of these forms of variation? Here, via parent–offspring sequencing of the peach we ask whether (i) woody perennials tend to have lower per unit time mutation rates compared to annuals and (ii) hybrid strains have high mutation rates. Between a leaf from a low heterozygosity individual, derived from an intraspecific cross, to a leaf of its selfed progeny, the mutation rate is 7.77 × 10−9 point mutations per bp per generation, similar to Arabidopsis thaliana (7.0–7.4 × 10−9 point mutations per bp per generation). This suggests a low per unit time mutation rate as the generation time is much longer in peach. This is supported by our estimate of 9.48 × 10−9 point mutations per bp per generation from a 200-year-old low heterozygosity peach to its progeny. From a more highly heterozygous individual derived from an interspecific cross to its selfed progeny, the mutation rate is 1.38 × 10−8 mutations per site per generation, consistent with raised rates in hybrids. Our data thus suggest that (i) peach has an approximately order of magnitude lower mutation rate per unit time than Arabidopsis, consistent with reports of low evolutionary rates in woody perennials, and (ii) hybridization may, indeed, be associated with increased mutation rates as considered over a century ago.
Electronic Supplementary material for ‘The influence of weather conditions during gestation on life histories in a wild Arctic ungulate’
Creators: name: Douhard, Mathieu
name: Loe, Leif Egil
name: Stien, Audun
name: Bonenfant, Christophe
name: R. Justin Irvine
name: Vebjørn Veiberg
name: Ropstad, Erik
name: Albon, Steve
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: This file contains 4 figures and 2 tables
Supplementary Figures and Tables from Mutation rate analysis via parent–progeny sequencing of the perennial peach I. A low rate in woody perennials and a higher mutagenicity in hybrids
Creators: name: Zhengqing Xie
name: Wang, Long
name: Lirong Wang
name: Zhiqiang Wang
name: Zhenhua Lu
name: Dacheng Tian
name: Sihai Yang
name: Hurst, Laurence D.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60408 Genomics

description: Mutation rates vary between species, between strains within species and between regions within a genome. What are the determinants of these forms of variation? Here, via parent–offspring sequencing of the peach we ask whether (i) woody perennials tend to have lower per unit time mutation rates compared to annuals and (ii) hybrid strains have high mutation rates. Between a leaf from a low heterozygosity individual, derived from an intraspecific cross, to a leaf of its selfed progeny, the mutation rate is 7.77 × 10−9 point mutations per bp per generation, similar to Arabidopsis thaliana (7.0–7.4 × 10−9 point mutations per bp per generation). This suggests a low per unit time mutation rate as the generation time is much longer in peach. This is supported by our estimate of 9.48 × 10−9 point mutations per bp per generation from a 200-year-old low heterozygosity peach to its progeny. From a more highly heterozygous individual derived from an interspecific cross to its selfed progeny, the mutation rate is 1.38 × 10−8 mutations per site per generation, consistent with raised rates in hybrids. Our data thus suggest that (i) peach has an approximately order of magnitude lower mutation rate per unit time than Arabidopsis, consistent with reports of low evolutionary rates in woody perennials, and (ii) hybridization may, indeed, be associated with increased mutation rates as considered over a century ago.
Additional results (associations between female status and androgens) and tables from Androgens predict parasitism in female meerkats: a new perspective on a classic trade-off
Creators: name: Smyth, Kendra N.
name: Greene, Lydia K.
name: Clutton-Brock, Tim
name: Drea, Christine M.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Additional results about the relationship between social and reproductive status and FAM concentrations; Tables of GLMM and GLM results for factors associated with infection status (Table S1) and abundance (Table S2)
CyberUnits Bricks 1.0 Documentation
Creators: name: Dietrich, Johannes Wolfgang Christian
Publisher: name: figshare
Year: 2016
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Biophysics
subject: Computational Biology
subject: 60304 Ethology and Sociobiology
subject: FOS: Biological sciences
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: 60113 Synthetic Biology
subject: 60114 Systems Biology
subject: 111602 Human Biophysics
subject: FOS: Basic medicine
subject: 111603 Systems Physiology
subject: 80301 Bioinformatics Software
subject: 80102 Artificial Life
subject: 80110 Simulation and Modelling

description: CyberUnits is a library of cross-platform units for medical cybernetics and systems biology.

The Bricks collection is a set of Pascal units that provides a class library for rapid programming of high-performance computer simulations in life sciences. It also delivers a class library that facilitates the generation of visual block diagrams in software.