cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Delayed diagnosis in X-linked agammaglobulinemia and its relationship to the occurrence of mutations in BTK non-kinase domains
Creators: name: Carrillo-Tapia, Eduardo
name: García-García, Elizabeth
name: Herrera-González, Norma Estela
name: Yamazaki-Nakashimada, Marco Antonio
name: Aidee Tamara Staines-Boone
name: Segura-Mendez, Nora Hilda
name: Scheffler-Mendoza, Selma Cecilia
name: O`Farrill-Romanillos, Patricia
name: Gonzalez-Serrano, Maria E
name: Rodriguez-Alba, Juan Carloa
name: Santos-Argumedo, Leopoldo
name: Berron-Ruiz, Laura
name: Sanchez-Flores, Alejandro
name: López-Herrera, Gabriela
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Background: X-linked agammaglobulinemia (XLA) is characterized by the absence of immunoglobulin and B cells. Patients suffer from recurrent bacterial infections from early childhood, and require lifelong immunoglobulin replacement therapy. Mutations in BTK (Bruton’s Tyrosine Kinase) are associated with this phenotype. Some patients that present XLA do not show typical clinical symptoms, resulting in delayed diagnosis due to the lack of a severe phenotype. This study presents a report of five XLA patients from four different families and attempts to determine a relationship between delayed diagnosis and the occurrence of BTK mutations. Methods: Samples from patients with antibody deficiency were analyzed to determine BTK expression, immunophenotyping and mutation analysis. Clinical and laboratory data was analyzed and presented for each patient. Results: Most patients presented here showed atypical clinical and laboratory data for XLA, including normal IgM, IgG, or IgA levels. Most patients expressed detectable BTK protein. Sequencing of BTK showed that these patients harbored missense mutations in the pleckstrin homology and Src-homology-2 domains. When it was compared to public databases, BTK sequencing exhibited a new change, along with three other previously reported changes. Conclusions: Delayed diagnosis and atypical manifestations in XLA might be related to mutation type and BTK expression.
Multiobjective Optimization of Solar Powered Irrigation System with Fuzzy Type-2 Noise Modelling
Creators: name: Ganesan, T.
name: Vasant, P.
name: Elamvazuthi, I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Optimization is becoming a crucial element in industrial applications involving sustainable alternative energy systems. During the design of such systems, the engineer/decision maker would often encounter noise factors (e.g. solar insolation and ambient temperature fluctuations) when their system interacts with the environment. In this chapter, the sizing and design optimization of the solar powered irrigation system was considered. This problem is multivariate, noisy, nonlinear and multiobjective. This design problem was tackled by first using the Fuzzy Type II approach to model the noise factors. Consequently, the Bacterial Foraging Algorithm (BFA) (in the context of a weighted sum framework) was employed to solve this multiobjective fuzzy design problem. This method was then used to construct the approximate Pareto frontier as well as to identify the best solution option in a fuzzy setting. Comprehensive analyses and discussions were performed on the generated numerical results with respect to the implemented solution methods.
description: 27 pages, 12 Figures
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00052
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00052, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
The Innovative Behaviour of Software Engineers: Findings from a Pilot Case Study
Creators: name: Monteiro, Cleviton
name: da Silva, Fabio Queda Bueno
name: Capretz, Luiz Fernando
Publisher: name: arXiv
Year: 2016
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Context: In the workplace, some individuals engage in the voluntary and intentional generation, promotion, and realization of new ideas for the benefit of individual performance, group effectiveness, or the organization. The literature classifies this phenomenon as innovative behaviour. Despite its importance to the development of innovation, innovative behaviour has not been fully investigated in software engineering. Objective: To understand the factors that support or inhibit innovative behaviour in software engineering practice. Method: We conducted a pilot case study in a Canadian software company using interviews and observations as data collection techniques. Using qualitative analysis, we identified relevant factors and relationships not addressed by studies from other areas. Results: Individual innovative behaviour is influenced by individual attitudes and also by situational factors such as relationships in the workplace, organizational characteristics, and project type. We built a model to express the interacting effects of these factors. Conclusions: Innovative behaviour is dependent on individual and contextual factors. Our results contribute to relevant impacts on research and practice, and to topics that deserve further study.
description: 10 pages
A Component-Based Simplex Architecture for High-Assurance Cyber-Physical Systems
Creators: name: Phan, Dung
name: Yang, Junxing
name: Clark, Matthew
name: Grosu, Radu
name: Schierman, John D.
name: Smolka, Scott A.
name: Stoller, Scott D.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: We present Component-Based Simplex Architecture (CBSA), a new framework for assuring the runtime safety of component-based cyber-physical systems (CPSs). CBSA integrates Assume-Guarantee (A-G) reasoning with the core principles of the Simplex control architecture to allow component-based CPSs to run advanced, uncertified controllers while still providing runtime assurance that A-G contracts and global properties are satisfied. In CBSA, multiple Simplex instances, which can be composed in a nested, serial or parallel manner, coordinate to assure system-wide properties. Combining A-G reasoning and the Simplex architecture is a challenging problem that yields significant benefits. By utilizing A-G contracts, we are able to compositionally determine the switching logic for CBSAs, thereby alleviating the state explosion encountered by other approaches. Another benefit is that we can use A-G proof rules to decompose the proof of system-wide safety assurance into sub-proofs corresponding to the component-based structure of the system architecture. We also introduce the notion of coordinated switching between Simplex instances, a key component of our compositional approach to reasoning about CBSA switching logic. We illustrate our framework with a component-based control system for a ground rover. We formally prove that the CBSA for this system guarantees energy safety (the rover never runs out of power), and collision freedom (the rover never collides with a stationary obstacle). We also consider a CBSA for the rover that guarantees mission completion: all target destinations visited within a prescribed amount of time.
description: Extended version of a paper to be presented at ACSD 2017, 12 pages, 3 figures, 1 appendix
P3 Cuisines Southern Comfort Foods
Creators: name: Southern Comfort Foods, P3 Cuisines
Publisher: name: Zenodo
Year: 2024

description: P3 Cuisine is a distinguished restaurant in Baltimore specializing in Cajun and Creole foods. Led by Chef Shonda Washington, who draws inspiration from her New Orleans upbringing and training in Italy, the restaurant offers a unique dining experience that blends simple ingredients with rich flavors. It stands out for its fusion of South Asian and Maryland soul food, featuring signature dishes like seafood, Po-boy sandwiches, and Creole specialties. P3 Cuisine, known for its warm ambiance and soulful essence, caters to a diverse clientele, aiming to deliver a delightful culinary journey with each dish.
Synthesis and antiproliferative activities of aminoalkylated polymethoxyflavonoid derivatives
Creators: name: Li, Xue-Li
name: Zhang, Yan-Hua
name: Wang, Cai-Fang
name: Qiu-An Wang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Hematology

description: A series of novel aminoalkylated polymethoxyflavonoid derivatives 3–11 was synthesised from 5-hydroxy-3,7,3′,4′-tetramethoxyflavonoid (1) through extending alkoxy chain at the 5-position, and introducing amine hydrogen bond receptor at the end of the side chain. Their antiproliferative activities were evaluated in vitro on a panel of three human cancer cell lines (Hela, HCC1954 and SK-OV-3). The results showed that all the target compounds exhibited antiproliferative activities against investigated cancer cells with IC50 values of 9.51–53.33 μM. Compounds 5, 7, 8, 11 on Hela cells and compounds 4–9, 11 on HCC1954 exhibited more potency as compared to positive control cis-Platin.
Gabor Filter Assisted Energy Efficient Fast Learning Convolutional Neural Networks
Creators: name: Sarwar, Syed Shakib
name: Panda, Priyadarshini
name: Roy, Kaushik
Publisher: name: arXiv
Year: 2017
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Convolutional Neural Networks (CNN) are being increasingly used in computer vision for a wide range of classification and recognition problems. However, training these large networks demands high computational time and energy requirements; hence, their energy-efficient implementation is of great interest. In this work, we reduce the training complexity of CNNs by replacing certain weight kernels of a CNN with Gabor filters. The convolutional layers use the Gabor filters as fixed weight kernels, which extracts intrinsic features, with regular trainable weight kernels. This combination creates a balanced system that gives better training performance in terms of energy and time, compared to the standalone CNN (without any Gabor kernels), in exchange for tolerable accuracy degradation. We show that the accuracy degradation can be mitigated by partially training the Gabor kernels, for a small fraction of the total training cycles. We evaluated the proposed approach on 4 benchmark applications. Simple tasks like face detection and character recognition (MNIST and TiCH), were implemented using LeNet architecture. While a more complex task of object recognition (CIFAR10) was implemented on a state of the art deep CNN (Network in Network) architecture. The proposed approach yields 1.31-1.53x improvement in training energy in comparison to conventional CNN implementation. We also obtain improvement up to 1.4x in training time, up to 2.23x in storage requirements, and up to 2.2x in memory access energy. The accuracy degradation suffered by the approximate implementations is within 0-3% of the baseline.
description: Accepted in ISLPED 2017
PROBONO-D9.2-Exploitation,_Replication_and_Sustainability_(I)-28042023-FINAL-PNO
Creators: name: Jiménez, Maria
Publisher: name: Zenodo
Year: 2023
Subjects: Sustainable development
Innovation management
Stakeholder engagement
Urban sustainability
Environmental impact

description: Attached is Deliverable D9.2 Exploitation, Replication, and Sustainability (I), formulating the preliminary findings of PROBONO’s exploitation plan. More specifically it focuses on three key concepts that have been developed within the project and that are mandatory for the sake of alignment and cohesion both within and beyond project activities. These work-in-progress concepts are the Green Building Neighbourhood – establishing the vision for liveable sustainable places,  the GBN Innovation Cluster – establishing the stakeholders and the motivations to set up GBNs in the near future, the International Ecosystem of GBN Innovation Clusters – establishing the network of best practices and alliances for GBNs across Europe and the globe. Moreover, as part of the exploitation planning of PROBONO, by the end of the first year of the project, a first assessment of project exploitable results was executed and listed in this public deliverable. The full exploitation pathways will be iteratively assessed during the project and will allow the identification of opportunities for results usage, boost PROBONO’s impact, and ultimately, maximize environmental sustainability in the built environment.
Form factors in the $\mathrm{B}_\mathrm{s} \rightarrow \mathrm{K} \ell ν$ decays using HQET and the lattice
Creators: name: Banerjee, Debasish
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We report on a recent computation of the form factors in semi-leptonic decays of the $\mathrm{B}_\mathrm{s}$ using Heavy Quark Effective Theory (HQET) formalism applied on the lattice. The connection of the form factors with the 2-point and 3-point correlators on the lattice is explained, and the subsequent non-perturbative renormalization of HQET and it's matching to $N_f=2$ QCD is outlined. The results of the (static) leading-order calculation in the continuum limit is presented.
description: On behalf on the ALPHA collaboration. Proceedings contribution to 34th annual International Symposium on Lattice Field Theory
Additional file 4: of Transcriptomic analysis reveals the regulatory module of apple (Malus Ă domestica) floral transition in response to 6-BA
Creators: name: Li, Youmei
name: Zhang, Dong
name: An, Na
name: Fan, Sheng
name: Zuo, Xiya
name: Zhang, Xin
name: Zhang, Lizhi
name: Gao, Cai
name: Han, Mingyu
name: Xing, Libo
Publisher: name: figshare
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Figure S2 Comparison of expression profiles of representative genes as measured by RNA-seq and qRT-PCR. Columns represent expression determined by qRT-PCR (left y-axis). (A) Relative expression was calculated using the ACTIN housekeeping gene. (B) Relative expression was calculated using the HISTONE housekeeping gene. Values represent the means Âą SE of 3 biological replicates.Lines represent expression by RNA-seq in relative to FPKM values at first sample time point (right y-axis). Circles represent 6-BA treatment group, triangle represent control group. Correlations between qRT-PCR and RNA-seq expressions were calculated and their associated P-values are indicated. (PDF 272 kb)
Particle-in-cell simulations of the relaxation of electron beams in inhomogeneous solar wind plasmas
Creators: name: Thurgood, J. O.
name: Tsiklauri, D.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: Previous theoretical considerations of electron beam relaxation in inhomogeneous plasmas have indicated that the effects of the irregular solar wind may account for the poor agreement of homogeneous modelling with the observations. Quasi-linear theory and Hamiltonian models based on Zakharov's equations have indicated that when a level of density fluctuations is above a given threshold, density irregularities act to de-resonate the beam-plasma interaction, restricting Langmuir wave growth on the expense of beam energy. This work presents the first fully kinetic particle-in-cell (PIC) simulations of beam relaxation under the influence of density irregularities. We aim to independently determine the influence of background inhomogeneity on the beam-plasma system, and to test theoretical predictions and alternative models using a fully kinetic treatment. We carry out 1D PIC simulations of a bump-on-tail unstable electron beam in the presence of increasing levels of background inhomogeneity using the fully electromagnetic, relativistic EPOCH PIC code. We find that in the case of homogeneous background plasma density, Langmuir wave packets are generated at the resonant condition and then quasi-liear relaxation leads to a dynamic increase of wavenumbers generated. No electron acceleration is seen - unlike in the inhomogeneous experiments, all of which produce high-energy electrons. For the inhomogeneous experiments we also observe the generation of backwards propagating Langmuir waves, which is shown directly to be due to the refraction of the packets off the density gradients. Our fully kinetic PIC simulations broadly confirm the findings of quasi-linear theory and the Hamiltonian model based on Zakharov's equations. Strong density fluctuations modify properties of excited Langmuir waves altering their dispersion properties.
description: Animations can be found at https://jonathanthurgood.wordpress.com/myresearch/thurgood-and-tsiklauri-2016-movies/
New coumarin from the roots of Prangos pabularia
Creators: name: Sodik Numonov
name: Khayrulla Bobakulov
name: Mukhabbat Numonova
name: Farukh Sharopov
name: Setzer, William N.
name: Qosimjon Khalilov
name: Nurmirza Begmatov
name: Maidina Habasi
name: Haji Akber Aisa
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 60506 Virology

description: The new coumarin 1, yuganin A (7-methoxy-8-((1S,2S)-1,2,3-trihydroxy-3-methylbutyl)-2H-chromen-2-one) along with nine known coumarins, heraclenol 3′-O-β-D-glucopyranoside (2), oxypeucedanin hydrate 3′-O-β-D-glucopyranoside (3), heraclenol (4), oxypeucedanin hydrate (5), osthole (6), oxypeucedanin (7), heraclenin (8), isoimperatorin (9), imperatorin (10) and the disaccharide sucrose (11), have been isolated from the roots of Prangos pabularia, and the structures of these isolated compounds were elucidated by spectroscopic means, especially, UV, HR-ESIMS, and 1D and 2D NMR spectroscopy. Furthermore, the anti-melanogenic effect of yuganin A and its inhibitory effect on B16 cells were evaluated. Yuganin A may be useful in the treatment of hyperpigmentation and as a skin-whitening agent in the cosmetics industry.
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0682
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0682, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0682, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 6: of Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment
Creators: name: Xu, Wanfu
name: Qian, Jiabi
name: Zeng, Fangyin
name: Li, Songyu
name: Guo, Wenjing
name: Chen, Liping
name: Li, Guihuan
name: Zhang, Zhishuai
name: Wang, Qiming
name: Deng, Fan
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Figure S4. Effect of PKD2 and PKD3 derived prostate cancer cells on endothelial cells tube formation in vitro. (PDF 832 kb)
Coordination of size-control, reproduction and generational memory in freshwater planarians
Creators: name: Yang, Xingbo
name: Kaj, Kelson J.
name: Schwab, David J.
name: Collins, Eva-Maria S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Uncovering the mechanisms that control size, growth, and division rates of systems reproducing through binary division means understanding basic principles of their life cycle. Recent work has focused on how division rates are regulated in bacteria and yeast, but this question has not yet been addressed in more complex, multicellular organisms. We have acquired a unique large-scale data set on the growth and asexual reproduction of two freshwater planarian species, Dugesia japonica and Dugesia tigrina, which reproduce by transverse fission and succeeding regeneration of head and tail pieces into new planarians. We show that generation-dependent memory effects in planarian reproduction need to be taken into account to accurately capture the experimental data. To achieve this, we developed a new additive model that mixes multiple size control strategies based on planarian size, growth, and time between divisions. Our model quantifies the proportions of each strategy in the mixed dynamics, revealing the ability of the two planarian species to utilize different strategies in a coordinated manner for size control. Additionally, we found that head and tail offspring of both species employ different mechanisms to monitor and trigger their reproduction cycles. Thus, we find a diversity of strategies not only between species but also between heads and tails within species. Our additive model provides two advantages over existing 2D models that fit a multivariable splitting rate function to the data for size control: Firstly, it can be fit to relatively small data sets and can thus be applied to systems where available data is limited. Secondly, it enables new biological insights because it explicitly shows the contributions of different size control strategies for each offspring type.
description: 26 pages, 10 figures
Chemical characterisation and hepatoprotective potential of Cosmos sulphureus Cav. and Cosmos bipinnatus Cav.
Creators: name: Saleem, Mohammad
name: Ali, Hafiz Akbar
name: Akhtar, Muhammad Furqan
name: Uzma Saleem
name: Ammara Saleem
name: Iram Irshad
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology
subject: 60506 Virology

description: This study was conducted to validate the hepatoprotective activity of Cosmos sulphureus and Cosmos bipinnatus. Aqua-methanolic extracts of both plants were evaluated for the presence of various phyto-constituents through HPLC. Different doses of both plant extracts were administered to rats for nine days. Standard control was silymarin 100 mg/kg. Paracetamol 1 gm/kg was administered 3 h post treatment on 9th day for induction of hepatotoxicity. Blood was collected for the evaluation of liver biochemical markers and livers were removed for histopathological evaluation 24 h post-paracetamol treatment. HPLC analysis revealed the presence of quercetin, gallic acid, caffeic acid and chlorogenic acid in both plant extracts. The extracts of both plants decreased the level of alanine aminotransaminase and total bilirubin significantly (p < 0.05), dose dependently and protected hepatocytes from paracetamol-induced hepatotoxicity. It can be concluded that both plants may possess hepatoprotective activity possibly due to the presence of quercetin and phenolic compounds.
Inertial migration and axial control of deformable capsules
Creators: name: Schaaf, Christian
name: Stark, Holger
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The mechanical deformability of single cells is an important indicator for various diseases such as cancer, blood diseases and inflammation. Lab-on-a-chip devices allow to separate such cells from healthy cells using hydrodynamic forces. We perform hydrodynamic simulations based on the lattice-Boltzmann method and study the behavior of an elastic capsule in a microfluidic channel flow in the inertial regime. While inertial lift forces drive the capsule away from the channel center, its deformability favors migration in the opposite direction. Balancing both migration mechanisms, a deformable capsule assembles at a specific equilibrium distance depending on its size and deformability. We find that this equilibrium distance is nearly independent of the channel Reynolds number and falls on a single master curve when plotted versus the Laplace number. We identify a similar master curve for varying particle radius. In contrast, the actual deformation of a capsule strongly depends on the Reynolds number. The lift-force profiles behave in a similar manner as those for rigid particles. Using the Saffman effect, the capsule's equilibrium position can be controlled by an external force along the channel axis. While rigid particles move to the center when slowed down, very soft capsules show the opposite behavior. Interestingly, for a specific control force particles are focused on the same equilibrium position independent of their deformability.
Additional file 2 of Genome-wide DNA methylation analysis of extreme phenotypes in the identification of novel epigenetic modifications in diabetic retinopathy
Creators: name: Yang, Shaopeng
name: Guo, Xiao
name: Cheng, Weijing
name: Seth, Ishith
name: Bulloch, Gabriella
name: Chen, Yifan
name: Shang, Xianwen
name: Zhu, Zhuoting
name: Huang, Wenyong
name: Wang, Wei
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Supplementary tables and figures.
Gravitational waves from neutron star excitations in binary inspirals
Creators: name: Parisi, A.
name: Sturani, R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In the context of binary inspiral of mixed neutron star - black hole systems, we investigate the excitation of the neutron star oscillation modes by the orbital motion. We study generic eccentric orbits and show that tidal interaction can excite the f-mode oscillations of the star by computing the amount of energy and angular momentum deposited into the star by the orbital motion tidal forces via closed form analytic expressions. We study the f-mode oscillations of cold neutron stars using recent microscopic nuclear equations of state, and we compute their imprint into the emitted gravitational waves.
description: 13 pages, 14 figures
A high spectral resolution map of the nuclear emitting regions of NGC 7582
Creators: name: Braito, Valentina
name: Reeves, James
name: Bianchi, Stefano
name: Nardini, Emanuele
name: Piconcelli, Enrico
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present the results of the spatial and spectral analysis of the deep (~200 ksec) Chandra HETG observation of the changing look AGN NGC7582. During this observation NGC7582 was in a highly obscured state. Therefore, we considered also a short Suzaku observation, which caught NGC7582 in a Compton thick state. This allows us to determine the underlying continuum and the amount of absorption ($N_H \sim~1.2\times10^{24}$ cm$^{-2}$). A wealth of emission lines are detected in the Chandra data, which allow us to map the structure of the circum-nuclear emitters. The high resolution spectrum reveals that the soft X-ray emission originates in a hybrid gas, which is ionized in part by the starforming activity and in part by the central AGN. The high resolution images confirm that the emitting region is inhomogeneous and extends up to a few hundred pc from the nuclear source. The X-ray images are more extended in the lower energy lines (Ne and Mg) than in the higher energy lines (Si, Fe), where the former are dominated by the collisionally ionised gas and the latter by the photoionized AGN emission. This is supported by the analysis of the He-like triplets. We deduce that a low density photoionized gas is responsible for the strong forbidden components, which is likely to originate from extended AGN Narrow Line Region gas at distances of 200-300 pc from the black hole. We also detected an absorption feature at ~ 6.7 keV consistent with the rest frame energy of the resonance absorption line from FeXXV, which traces the presence of a sub-parsec scale ionized absorber. The emerging picture is in agreement with our view of the circumnuclear gas in AGN, where the medium is clumpy and stratified in both density and ionization. These absorbers and emitters are located on different scales: from the sub-pc Broad Line Region gas out to the kpc scale of the galactic absorber.
description: 15 pages, including 9 figures. Accepted for publication in Astronomy & Astrophysics
ESTEEM DENTAL AND ORTHODONTICS
Creators: name: ESTEEM DENTAL AND ORTHODONTICS
Publisher: name: Zenodo
Year: 2024

description: At Esteem Dental, we can redefine the path to a stunning smile through modern orthodontics. Invisalign is an innovative alternative to traditional braces, offering a discreet and convenient way to align your teeth. It enhances your appearance and promotes better oral health. As you embark on this journey, it’s essential to understand that preparing for Invisalign involves a commitment to maintaining oral hygiene and adhering to the specific care instructions for your aligners. 

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Measuring and improving student engagement in clinical training
Creators: name: Lee, Simin
name: Valtis, Yannis K.
name: Jun, Tomi
name: Wang, David
name: Biqi Zhang
name: Chung, Esther H.
name: Yu, Amy
name: Williams, Rachael
name: Cohen, Marya J.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Purpose: Volunteer service learning activities, including Student Run Clinics (SRCs), are becoming an increasingly popular extracurricular component of medical education. While there are reports that student clinicians generally enjoy their educational experiences at SRCs, it is not understood how to optimize and measure student engagement in them. To identify key drivers of student engagement a tool was created to measure volunteer experience at the Crimson Care Collaborative (CCC), a primary care SRC. Methods: CCC volunteers were asked to complete an online engagement survey. Cross-sectional survey data were collected for 149 CCC volunteers (53% response rate). Results: Multivariate linear regression showed that overall ‘likelihood to recommend CCC to a friend’ was significantly associated with students’ perception of the clarity of their role within the clinic, frequency of interprofessional interactions, and overall quality of medical education. Students who volunteer more frequently and for longer periods of time had higher engagement scores. Conclusions: Measuring engagement is feasible in volunteer settings. Engagement appears to be dependent on both structural and experiential components. Easily modifiable components of job design (role definition, expected frequency of volunteering), are key drivers of volunteer engagement.
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00696
Creators: name: de la Côte-d'Or, Archives départementales
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00696, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Measuring and improving student engagement in clinical training
Creators: name: Lee, Simin
name: Valtis, Yannis K.
name: Jun, Tomi
name: Wang, David
name: Biqi Zhang
name: Chung, Esther H.
name: Yu, Amy
name: Williams, Rachael
name: Cohen, Marya J.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Volunteer service learning activities, including Student Run Clinics (SRCs), are becoming an increasingly popular extracurricular component of medical education. While there are reports that student clinicians generally enjoy their educational experiences at SRCs, it is not understood how to optimize and measure student engagement in them. To identify key drivers of student engagement a tool was created to measure volunteer experience at the Crimson Care Collaborative (CCC), a primary care SRC. CCC volunteers were asked to complete an online engagement survey. Cross-sectional survey data were collected for 149 CCC volunteers (53% response rate). Multivariate linear regression showed that overall ‘likelihood to recommend CCC to a friend’ was significantly associated with students’ perception of the clarity of their role within the clinic, frequency of interprofessional interactions, and overall quality of medical education. Students who volunteer more frequently and for longer periods of time had higher engagement scores. Measuring engagement is feasible in volunteer settings. Engagement appears to be dependent on both structural and experiential components. Easily modifiable components of job design (role definition, expected frequency of volunteering), are key drivers of volunteer engagement.
Towards Effective Bug Triage with Towards Effective Bug Triage with Software Data Reduction Techniques
Creators: name: Xuan, Jifeng
name: Jiang, He
name: Hu, Yan
name: Ren, Zhilei
name: Zou, Weiqin
name: Luo, Zhongxuan
name: Wu, Xindong
Publisher: name: arXiv
Year: 2017
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Software companies spend over 45 percent of cost in dealing with software bugs. An inevitable step of fixing bugs is bug triage, which aims to correctly assign a developer to a new bug. To decrease the time cost in manual work, text classification techniques are applied to conduct automatic bug triage. In this paper, we address the problem of data reduction for bug triage, i.e., how to reduce the scale and improve the quality of bug data. We combine instance selection with feature selection to simultaneously reduce data scale on the bug dimension and the word dimension. To determine the order of applying instance selection and feature selection, we extract attributes from historical bug data sets and build a predictive model for a new bug data set. We empirically investigate the performance of data reduction on totally 600,000 bug reports of two large open source projects, namely Eclipse and Mozilla. The results show that our data reduction can effectively reduce the data scale and improve the accuracy of bug triage. Our work provides an approach to leveraging techniques on data processing to form reduced and high-quality bug data in software development and maintenance.
description: 17 pages, 7 figures
Structure determination and quantification of a new flavone glycoside with anti-acetylcholinesterase activity from the herbs of Elsholtzia ciliata
Creators: name: Agung Nugroho
name: Jong-Hyuk Park
name: Choi, Jae Sue
name: Kyoung-Sik Park
name: Joon-Pyo Hong
name: Hee-Juhn Park
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology

description: Three acacetin triglycosides (compounds 1, 2 and 3) were isolated from the herbs of Elsholtzia ciliata (Labiatae). The structure were identified as 7-O-β-D-glucopyranosyl-(1 → 2)[α-L-rhamnopyranosyl-(1 → 6)]-β-D-glucopyranoside (compound 1), 7-O-(6-O-acetyl)-β-D-glucopyranosyl-(1 → 2)[α-L-rhamnopyranosyl-(1 → 6)]-β-D-glucopyranoside (compound 2) and 7-O-(6-O-acetyl)-β-D-glucopyranosyl-(1 → 2)[(4-O-acetyl)-α-L-rhamnopyranosyl-(1 → 6)]-β-D-glucopyranoside (compound 3) of acacetin. The structures of these compounds were determined on the basis of 2D-NMR spectroscopic data. Compound 3 has not been isolated from a natural source. In addition, the three compounds were quantitatively analysed by HPLC. Acetylcholinesterase (AChE) inhibition activity was assayed to find anti-Alzheimer’s activity, since this enzyme increases the concentration of acetylcholine (ACh), a neurotransmitter, responsible for brain’s memory. Acacetin, the aglycone of the three compounds, exhibited a potent anti-cholinesterase activity (IC50, 50.33 ± 0.87), though its glycosides (1, 2 and 3) were less active. HPLC analysis demonstrated that the three compounds were contained in the MeOH extract in the order of compounds 2 (12.63 mg/g extract) > 3 (3.10 mg/g) > 1 (2.92 mg/g).
Best Packer And Removal Company In Oman – AUC Logistics
Creators: name: AUC Logistics
Publisher: name: Zenodo
Year: 2024

description: Searching for the best packer and removal company in Oman? Finding a reliable removal and packer company in Oman can make your move smooth and stress-free. With several options available, it's important to research and compare services to find the best fit for your needs.

Read More: https://auclogistics.co/packing-removals-services-in-oman/
Searching for a pair of accreting supermassive black holes in J1425+3231
Creators: name: Gabányi, K. É.
name: Frey, S.
name: Paragi, Z.
name: An, T.
name: Komossa, S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In hierarchical structure formation scenarios, merging galaxies are expected to be seen in different phases of their coalescence. Simulations suggest that simultaneous activity of the supermassive black holes (SMBHs) in the centres of the merging galaxies may be expected at kpc-scale separations. Currently, there are no direct observational methods which allow the selection of a large number of such dual active galactic nuclei (AGN) candidates. SDSS J142507.32+323137.4 was reported as a promising candidate source based on its optical spectrum. Here we report on our sensitive e-MERLIN observations performed at $1.6$ and at $5$ GHz, which show that the optical spectrum of the source can be more straightforwardly explained with jet-cloud interactions instead of the dual AGN scenario.
description: 4 pages, 1 figure. Accepted for publication in the Proceedings of the IAU Symposium No. 324, New Frontiers in Black Hole Astrophysics
title: ADCO, Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Cart. 173 (11 H 939), 226 folios, f. 0111
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0111, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0111, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
A multiplier theorem for sub-Laplacians with drift on Lie groups
Creators: name: Martini, Alessio
name: Ottazzi, Alessandro
name: Vallarino, Maria
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 22E30, 42B15, 42B20, 43A22

description: We prove a general multiplier theorem for symmetric left-invariant sub-Laplacians with drift on non-compact Lie groups. This considerably improves and extends a result by Hebisch, Mauceri, and Meda. Applications include groups of polynomial growth and solvable extensions of stratified groups.
Evaluation of genotoxic and modulatory effects of Nyctanthes arbor-tristis calyx extract and the isolated crocin in Ames’ assay
Creators: name: Pawar, Neha
name: Shital Panchal
name: Dhananjay Kawle
name: Gadgoli, Chhaya
name: Girish Maru
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Flowers of the plant Nyctanthes arbor-tristis (NAT) are widely used in the traditional medicinal systems of several Asian countries. In the present study, potential genotoxicity and modulatory effects of ethanolic extract of NAT flower calyx (NAT FCE) and crocin, a carotenoid principle were evaluated employing standard Salmonella assay. Experiments evaluating the genotoxic potential of NAT FCE and crocin, with and without the S9-activation in TA 98, TA 100 and TA 102 showed a lack of increase in revertant mutants. Evaluation of modulatory effects of NAT FCE and crocin, without the S9, showed significant decrease in the number of 4-nitro-o-phenylenediamine-, sodium azide- and ethyl methanesulfonate-induced revertants. However, with S9, NAT FCE and crocin moderately increased the 2-aminoanthracene-induced revertants in TA 98; they moderately decreased revertants in TA 100 and TA 102. Both NAT FCE and crocin have been shown to be non-genotoxic and to be able to modulate responses of standard mutagens.
Compiled Toolbox Talks Vol. 2
Creators: name: Bascom, Carlene
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 410403
subject: Environmental education and extension
classificationCode: 350505
subject: Occupational and workplace health and safety

description: “Toolbox Talks are a critical part of the HSE training regimen of any Construction Project or Operation.” Carlene R. Bascom