cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Book Review of World Trade Law.pdf
Creators: name: Malkawi, Bashar H.
Publisher: name: figshare
Year: 2018
Subjects: subject: 180105 Commercial and Contract Law
subject: FOS: Law

description: The World Trade Organization (WTO) has attracted considerable interest. Since its creation in 1994, the WTO brought with it legalization of world trade politics after its predecessor, the General Agreement of Tariffs and Trade (GATT), was considered a geopolitical document to contain the spread of non-market ideology to other countries. Not only does the WTO cover traditional subjects such as tariffs and nontariff barriers but also it covers intellectual property, services, and trade-related investment measures.
Additional file 3 of Construction and validation of a prognostic model of RNA binding proteins in clear cell renal carcinoma
Creators: name: Han, Wenkai
name: Fan, Bohao
name: Huang, Yongsheng
name: Wang, Xiongbao
name: Zhang, Zhao
name: Gu, Gangli
name: Liu, Zhao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Additional file 3: Supplement Table 3: Number of nodes in the PPI network.
Anatomy of the Case of Arab Countries and the WTO Bashar H. Malkawi.pdf
Creators: name: Malkawi, Bashar H.
Publisher: name: figshare
Year: 2018
Subjects: subject: 180105 Commercial and Contract Law
subject: FOS: Law
subject: Law

description: Arab countries are attempting to broaden their engagement in the multilateral trading system in a manner that has many implications.
Co-designing Interactive Technologies for Community Aware Physical Training and Rehabilitation in the VR2Care Digital Ecosystem
Creators: name: Qbilat, Malak
name: Van Berlo, Ad
name: Mota, Telma
name: de Carvalho, Fausto
name: de Luca, Vicenzo
name: Cesaroni, Francesca
name: Arendse, Matthieu
name: Mota, Vânia
Publisher: name: Zenodo
Year: 2024

description: This paper discuss the system desing options and the architectural challenges to support the VR2CARE digital ecosystem.
Benchmarking and Regulation of Electricity Transmission and Distribution Utilities: Lessons from International Experience
Creators: name: Jamasb, Tooraj
name: Pollitt, Michael G.
Publisher: name: Faculty of Economics
Year: 2004
Subjects: subject: Classification-JEL: L43, L51, L94
subject: electricity, benchmarking, incentive regulation, data envelopment analysis, stochastic frontier analysis

description: Since the early 1980's, many countries have implemented electricity sector reform, many of which have bundled generation, transmission, distribution and supply activities, and have introduced competition in generation and supply. An increasing number of countries are also adopting incentive regulation to promote efficiency improvement in the natural monopoly activities - transmission and distribution. Incentive regulation almost invariably involves benchmarking or comparison of actual vs. some reference performance. This paper reviews the main approaches to incentive regulation and discusses various benchmarking methods. We also present the finding of a survey of the use of benchmarking methods in the OECD and few other countries. Our survey finds a variety of methods used by the electricity regulators although with a notable preference for the non-parametric methods. We then draw conclusions based on the finding of the survey highlighting the main outstanding issues and lessons for best practice implementation of benchmarking in electricity regulation.
Replica Symmetry Breaking in Renormalization: Application to the Randomly Pinned Planar Flux Array
Creators: name: Kierfeld, Jan
Publisher: name: arXiv
Year: 1995
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: The randomly pinned planar flux line array is supposed to show a phase transition to a vortex glass phase at low temperatures. This transition has been examined by using a mapping onto a 2D XY-model with random an\-iso\-tropy but without vortices and applying a renormalization group treatment to the replicated Hamiltonian based on the mapping to a Coulomb gas of vector charges. This renormalization group approach is extended by deriving renormalization group flow equations which take into account the possibility of a one-step replica symmetry breaking. It is shown that the renormalization group flow is unstable with respect to replica asymmetric perturbations and new fixed points with a broken replica symmetry are obtained. Approaching these fixed points the system can optimize its free energy contributions from fluctuations on large length scales; an optimal block size parameter $m$ can be found. Correlation functions for the case of a broken replica symmetry can be calculated. We obtain both correlations diverging as $\ln{r}$ and $\ln^2{r}$ depending on the choice of $m$.
description: 14 pages, LaTeX, 1 uuencoded PostScript figure (accepted at 15 Nov 94 for publication in March 95 issue of J. Phys. I France)
Leading Particle Production in Light Flavour Jets
Creators: name: The OPAL Collaboration
name: Abbiendi, G.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The energy distribution and type of the particle with the highest momentum in quark jets are determined for each of the five quark flavours making only minimal model assumptions. The analysis is based on a large statistics sample of hadronic Z0 decays collected with the OPAL detector at the LEP e+e- collider. These results provide a basis for future studies of light flavour production at other centre-of-mass energies. We use our results to study the hadronisation mechanism in light flavour jets and compare the data to the QCD models JETSET and HERWIG. Within the JETSET model we also directly determine the suppression of strange quarks to be gamma_s=0.422+-0.049 (stat.)+-0.059 (syst.) by comparing the production of charged and neutral kaons in strange and non-strange light quark events. Finally we study the features of baryon production.
description: 34 pages, 8 figures; submitted to Eur. Phys. Jour. C
Unleashing the binding interaction of chrysin-Cu(II) complex with the biomacromolecular targets: further studies of cell cytotoxicity and radical scavenging properties
Creators: name: Sarmah, Sharat
name: Konthoujam, Ibemhanbi
name: Prakash, Vivek
name: Aguan, Kripamoy
name: Roy, Atanu Singha
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biophysics
Biochemistry
Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Mental Health

description: Flavonoids are significant dietary components and have ability to coordinate with metal ions to produce novel drug discovery leads that are superior to those of the parent flavonoids. Here, in this report, we have synthesized chrysin-Cu(II) complex (as per reported article) and characterized it further with different analytical techniques. The synthesized complex was evaluated for radical scavenging and cell cytotoxicity studies where it exhibited enhanced activity as compared to bare chrysin. The interaction studies of the complex with ct-DNA (Kb ⁓ 105 M−1), human serum albumin (HSA) and ovalbumin (Kb ⁓ 104 M−1) were evaluated using multi-spectroscopic and molecular docking studies. Groove binding mode with ct-DNA was observed as confirmed from competitive displacement studies, viscosity measurement, melting temperature estimation and docking analyses. The complex exhibited comparatively higher affinity towards ct-DNA which indicated it efficient transportation by the carrier proteins and controlled release in the target DNA.
Recommending Insightful Comments for Source Code using Crowdsourced Knowledge
Creators: name: Rahman, Mohammad Masudur
name: Roy, Chanchal K.
name: Keivanloo, Iman
Publisher: name: arXiv
Year: 2018
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Recently, automatic code comment generation is proposed to facilitate program comprehension. Existing code comment generation techniques focus on describing the functionality of the source code. However, there are other aspects such as insights about quality or issues of the code, which are overlooked by earlier approaches. In this paper, we describe a mining approach that recommends insightful comments about the quality, deficiencies or scopes for further improvement of the source code. First, we conduct an exploratory study that motivates crowdsourced knowledge from Stack Overflow discussions as a potential resource for source code comment recommendation. Second, based on the findings from the exploratory study, we propose a heuristic-based technique for mining insightful comments from Stack Overflow Q & A site for source code comment recommendation. Experiments with 292 Stack Overflow code segments and 5,039 discussion comments show that our approach has a promising recall of 85.42%. We also conducted a complementary user study which confirms the accuracy and usefulness of the recommended comments.
description: The 15th IEEE International Working Conference on Source Code Analysis and Manipulation (SCAM 2015), pp. 81--90, Bremen, Germany, September 2015
N=1 supersymmetric SU(4)xSU(2)LxSU(2)R effective theory from the weakly coupled heterotic superstring
Creators: name: Leontaris, G. K.
name: Rizos, J.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the context of the free-fermionic formulation of the heterotic superstring, we construct a three generation N=1 supersymmetric SU(4)xSU(2)LxSU(2)R model supplemented by an SU(8) hidden gauge symmetry and five Abelian factors. The symmetry breaking to the standard model is achieved using vacuum expectation values of a Higgs pair in (4bar,2R)+(4,2R) at a high scale. One linear combination of the Abelian symmetries is anomalous and is broken by vacuum expectation values of singlet fields along the flat directions of the superpotential. All consistent string vacua of the model are completely classified by solving the corresponding system of F- and D-flatness equations including non-renormalizable terms up to sixth order. The requirement of existence of electroweak massless doublets further restricts the phenomenologically viable vacua. The third generation fermions receive masses from the tree-level superpotential. Further, a complete calculation of all non-renormalizable fermion mass terms up to fifth order shows that in certain string vacua the hierarchy of the fermion families is naturally obtained in the model as the second and third generation fermions earn their mass from fourth and fifth order terms. Along certain flat directions it is shown that the ratio of the SU(4) breaking scale and the reduced Planck mass is equal to the up quark ratio m_c/m_t at the string scale. An additional prediction of the model, is the existence of a U(1) symmetry carried by the fields of the hidden sector, ensuring thus the stability of the lightest hidden state. It is proposed that the hidden states may account for the invisible matter of the universe.
description: Latex2e file, 50 pages, uses rotating.sty
Additional file 1 of Construction and validation of a prognostic model of RNA binding proteins in clear cell renal carcinoma
Creators: name: Han, Wenkai
name: Fan, Bohao
name: Huang, Yongshen
name: Wang, Xiongbao
name: Zhang, Zhao
name: Gu, Gangli
name: Liu, Zhao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Additional file 1: Supplement Table 1. The 1542 RBPs genes in human cells.
Chiral baryon in the coherent pair approximation
Creators: name: Aly, T. S. T.
name: McNeil, J. A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We revisit the work of K. Goeke, M. Harvey, F. Grümmer, and J. N. Urbano (Phys. Rev. {\bf D37}, 754 (1988)) who considered a chiral model for the nucleon based on the linear sigma model with scalar-isoscalar scalar-isovector mesons coupled to quarks and solved using the coherent-pair approximation. In this way the quantum pion field can be treated in a non-perturbative fashion. In this work we review this model and the coherent pair approximation correcting several errors in the earlier work. We minimize the expectation value of the chiral hamiltonian in the ansatz coherent-pair ground state configuration and solve the resulting equations for nucleon quantum numbers. We calculate the canonical set of nucleon observables and compare with the Hedgehog model and experiment. Using the corrected equations yield slightly different values for nucleon observables but do not correct the large virial deviation in the $π$-nucleon coupling. Our results therefore do not significantly alter the conclusions of Goeke, et al..
description: RevTeX, 24 pages, 5 figures
Introducing Competition in the French Electricity Supply Industry: The Destabilisation of a Public Hierarchy in an Open Institutional Environment
Creators: name: Finon, Dominique
Publisher: name: Faculty of Economics
Year: 2004
Subjects: subject: Classification-JEL: L14, L22, L51, L94, L98
subject: regulation, electricity

description: The French electricity supply industry is characterized by a vertically integrated monopoly and public ownership and when the government introduced market rules, it was with the aim of preserving the integration of the public incumbent as a national champion. This had two paradoxical effects in favour of competition development and the building of safeguards for entrants:
Lifetimes of Xi_{bc}^{+} and Xi_{bc}^{0} baryons
Creators: name: Kiselev, V. V.
name: Likhoded, A. K.
name: Onishchenko, A. I.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Estimates of lifetimes and partial branching ratios for the baryons $Ξ_{bc}^{+}$ and $Ξ_{bc}^{0}$ are presented using the inverse heavy quark mass expansion technique carried out in the Operator Product Expansion approach. We take into account both the perturbative QCD corrections to the spectator contributions and, depending on the quark contents of hadrons, the Pauli interference and weak scattering effects between the constituents, using a potential model for the evaluation of the non-perturbative parameters.
description: 15 pages, LATEX file, 2 eps-figures
Graphene Composites with Dual Functionality: Electromagnetic Shielding and Thermal Management
Creators: name: Kargar, Fariborz
name: Barani, Zahra
name: Balinskiy, Michael G.
name: Magana, Andres Sanchez
name: Lewis, Jacob S.
name: Balandin, Alexander A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Applied Physics (physics.app-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report on the synthesis and characterization of the epoxy-based composites with the few-layer graphene fillers, which are capable of the duel functional applications. It was found that composites with the certain types of few-layer graphene fillers reveal an efficient total electromagnetic interference shielding, SE~45 dB, in the important X-band frequency range, f=8.2 GHz - 12.4 GHz, while simultaneously providing the high thermal conductivity, K = 8 W/mK, which is a factor of x35 larger than that of the base matrix material. The efficiency of the dual functional application depends on the filler characteristics: thickness, lateral dimensions, aspect ratio and concentration. Graphene loading fractions above the percolation threshold allow for strong enhancement of both the electromagnetic interference shielding and heat conduction properties. Interestingly, graphene composites can block the electromagnetic energy even below the percolation threshold, remaining electrically insulating, which is an important feature for some types of thermal interface materials. The dual functionality of the graphene composites can substantially improve the electromagnetic shielding and thermal management of the airborne systems while simultaneously reducing their weight and cost.
description: 24 pages; 4 figures
MOESM1 of An innovative anti-cancer Chinese herbal formula exhibited multi-targeted efficacies in metastatic breast cancer mouse model
Creators: name: Yue, Grace
name: Lee, Julia
name: Chan, Ben
name: Hin-Fai Kwok
name: Hoi, Sandy
name: Sze, Daniel
name: Kwok-Pui Fung
name: Ping-Chung Leung
name: Lau, Clara
Publisher: name: figshare
Year: 2018
Subjects: subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy

description: Additional file 1. Minimum standards of reporting checklist.
Non-nested Models and the likelihood Ratio Statistic: A Comparison of Simulation and Bootstrap-based Tests
Creators: name: Kapetanios, George
name: Weeks, Melvyn
Publisher: name: Faculty of Economics
Year: 2004
Subjects: subject: Classification-JEL: C15, C52
subject: Non-nested tests, simulation-based inference, bootstrap tests, nonlinear threshold models

description: We consider an alternative use of simulation in the context of using the Likelihood-Ratio statistic to test non-nested models. To date simulation has been used to estimate the Kullback-Leibler measure of closeness between two densities, which in turn �mean adjusts� the Likelihood-Ratio statistic. Given that this adjustment is still based upon asymptotic arguments, an alternative procedure is to utilise bootstrap procedures to construct the empirical density. To our knowledge this study represents the first comparison of the properties of bootstrap and simulation-based tests applied to non-nested tests. More specifically, the design of experiments allows us to comment on the relative performance of these two testing frameworks across models with varying degrees of nonlinearity. In this respect although the primary focus of the paper is upon the relative evaluation of simulation and bootstrap-based nonnested procedures in testing across a class of nonlinear threshold models, the inclusion of a similar analysis of the more standard linear/log-linear models provides a point of comparison.
Molecular docking, molecular dynamics simulation, and MM/PBSA analysis of ginger phytocompounds as a potential inhibitor of AcrB for treating multidrug-resistant Klebsiella pneumoniae infections
Creators: name: Sahoo, Maheswata
name: Behera, Dibyajyoti Uttameswar
name: Gaur, Mahendra
name: Subudhi, Enketeswara
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biophysics
Biochemistry
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The emergence of Multidrug resistance (MDR) in human pathogens has defected the existing antibiotics and compelled us to understand more about the basic science behind alternate anti-infective drug discovery. Soon, proteome analysis identified AcrB efflux pump protein as a promising drug target using plant-driven phytocompounds used in traditional medicine systems with lesser side effects. Thus, the present study aims to explore the novel, less toxic, and natural inhibitors of Klebsiella pneumoniae AcrB pump protein from 69 Zingiber officinale phyto-molecules available in the SpiceRx database through computational-biology approaches. AcrB protein’s homology-modelling was carried out to get a 3D structure. The multistep-docking (HTVS, SP, and XP) were employed to eliminate less-suitable compounds in each step based on the docking score. The chosen hit-compounds underwent induced-fit docking (IFD). Based on the XP GScore, the top three compounds, epicatechin (−10.78), 6-gingerol (−9.71), and quercetin (−9.09) kcal/mol, were selected for further calculation of binding free energy (MM/GBSA). Furthermore, the short-listed compounds were assessed for their drug-like properties based on in silico ADMET properties and Pa, Pi values. In addition, the molecular dynamics simulation (MDS) studies for 250 ns elucidated the binding mechanism of epicatechin, 6-gingerol, and quercetin to AcrB. From the dynamic binding free energy calculations using MM/PBSA, 6-gingerol exhibited a strong binding affinity towards AcrB. Further, the 6-gingerol complex’s energy fluctuation was observed from the free energy landscape. In conclusion, 6-gingerol has a promising inhibiting potential against the AcrB efflux pump and thus necessitates further validation through in vitro and in vivo experiments.
Energy Barriers to Motion of Flux Lines in Random Media
Creators: name: Mikheev, Lev V.
name: Drossel, Barbara
name: Kardar, Mehran
Publisher: name: arXiv
Year: 1995
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We propose algorithms for determining both lower and upper bounds for the energy barriers encountered by a flux line in moving through a two-dimensional random potential. Analytical arguments, supported by numerical simulations, suggest that these bounds scale with the length $t$ of the line as $t^{1/3}$ and $t^{1/3}\sqrt{\ln t}$, respectively. This provides the first confirmation of the hypothesis that barriers have the same scaling as the fluctuation in the free energy. \pacs{PACS numbers: 74.60.Ge, 05.70.Ln, 05.40.+j}
description: 4 pages Revtex, 2 figures, to appear in PRL 75, 1170 (1995)
Using GATT Security Exception for Brexit.pdf
Creators: name: Malkawi, Bashar H.
Publisher: name: figshare
Year: 2018
Subjects: Economics

description: A key part of Brexit negotiations was about the border that separates Northern Ireland and the Republic of Ireland. The UK and Ireland are currently part of the EU single market and customs union so goods do not need to be inspected for customs and standards.
Of course, the backstop agreement must be approved by the UK Commons and is likely to face defeat as it is. Theoretically, the UK could utilize GATT article XXI claiming "essential national security" to permit goods and services passing from the Republic of Ireland tariff-free access and with few restrictions into Northern Ireland. Though it is plausible and can be adopted, this may sound childlike national securityargument.
Additional file 5 of Construction and validation of a prognostic model of RNA binding proteins in clear cell renal carcinoma
Creators: name: Han, Wenkai
name: Fan, Bohao
name: Huang, Yongshen
name: Wang, Xiongbao
name: Zhang, Zhao
name: Gu, Gangli
name: Liu, Zhao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Additional file 5. RNA extraction from tissues.
Formation of hot subdwarf B stars with neutron star components
Creators: name: Wu, You
name: Chen, Xuefei
name: Li, Zhenwei
name: Han, Zhanwen
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Binary population synthesis predicts the existence of subdwarf B stars (sdBs) with neutron star (NS) or black hole (BH) companions. We systematically investigate the formation of sdB+NS binaries from binary evolution and aim to obtain some clues for a search for such systems. We started from a series of MS+NS systems and determined the parameter spaces for producing sdB+NS binaries from the stable Roche-lobe overflow (RLOF) channel and from the common envelope (CE) ejection channel. Various NS accretion efficiencies and NS masses were examined to investigate the effects they have. We show the characteristics of the produced sdB+NS systems, such as the mass of components, orbital period, the semi-amplitude of the radial velocity (K), and the spin of the NS component. In the stable RLOF channel, the orbital period of sdB+NS binaries produced in this way ranges from several days to more than 1000 days and moves toward the short-period (~ hr) side with increasing initial MS mass. the sdB+NS systems that result from CE ejection have very short orbital periods and then high values of K (up to 800km s^-1). Such systems are born in very young populations (younger than 0.3 Gyr) and are potential gravitational wave sources that might be resolved by the Laser Interferometer Space Antenna (LISA) in the future. Gravitational wave radiation may again bring them into contact on a timescale of only ~Myr. As a consequence, they are rare and hard to discover. The pulsar signal is likely a feature of sdB+NS systems caused by stable RLOF, and some NS components in sdB binaries may be millisecond pulsars.
description: 12 pages, 6 figures, 4 tables. Accepted for publication in A&A
Recognition of human telomeric G-quadruplex DNA by 1,5-disubstituted diethyl-amido anthraquinone derivative in different ion environments causing thermal stabilization and apoptosis
Creators: name: Kumari, Anjana
name: Pandav, Kumud
name: Nath, Mala
name: Barthwal, Ritu
name: Peddinti, Rama Krishna
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biophysics
Biochemistry
Space Science
Physical Sciences not elsewhere classified
Cell Biology
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer

description: Ligand binding to G-quadruplex (G4) structures at human telomeric DNA ends promotes thermal stabilization, disrupting the interaction of the telomerase enzyme, which is found active in 80–85% of cancers and serves as a molecular marker. Anthraquinone compounds are well-known G-quadruplex (G4) binders that inhibit telomerase and induce apoptosis in cancer cells. Our current investigation is based on 1,5-bis[3-(diethylamino)propionamido]anthracene-9,10-dione, a derivative of anthraquinone and its binding characterization with two different human telomeric DNA structures, wHTel26 and HTel22, in the effect of K+ and Na+ by using an array of biophysical, calorimetry, molecular docking and cell viability assay techniques. Binding constants (Kb) in the range of ∼105–107 M−1 and stoichiometries of 1:1, 2:1 & 4:1 were obtained from the absorbance, fluorescence, and circular dichroism study. Remarkable hypochromism (55, 97%) and ∼17 nm shift in absorbance, fluorescence quenching (95, 97%), the unaltered value of fluorescence lifetime, restoration of Circular Dichroism bands, absence of ICD band, indicated the external groove binding/binding somewhere at loops. This is also evident in molecular docking results, the ligand binds to groove forming base (G4, G5, G24, T25) and in the vicinity to TTA loop (G14, G15, T17) bases of wHTel26 and HTel22, respectively. Thermal stabilization induced by ligand was found greater in Na+ ion (27.5 °C) than (19.1 °C) in K+ ion. Ligand caused cell toxicity in MCF-7 cancer cell lines with an IC50 value of ∼8.4 µM. The above findings suggest the ligand, 1,5-bis[3-(diethylamino)propionamido]anthracene-9,10-dione could be a potent anticancer drug candidate and has great therapeutic implications. Binding of disubstituted amido anthraquinone derivative, 1,5-bis[3-(diethylamino)propionamido]anthracene-9,10-dione to human telomere HTel22 antiparallel conformation induced thermal stabilization.
QCD Analyses and determinations of alpha-s in e+e- Annihilation at energies between 35 and 189 GeV
Creators: name: Jade, The
name: collaborations, the OPAL
name: Pfeifenschneider, P.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We employ data taken by the JADE and OPAL experiments for an integrated QCD study in hadronic e+e- annihilations at c.m.s. energies ranging from 35 GeV through 189 GeV. The study is based on jet-multiplicity related observables. The observables are obtained to high jet resolution scales with the JADE, Durham, Cambridge and cone jet finders, and compared with the predictions of various QCD and Monte Carlo models. The strong coupling strength, alpha_s, is determined at each energy by fits of O(alpha_s^2) calculations, as well as matched O(alpha_s^2) and NLLA predictions, to the data. Matching schemes are compared, and the dependence of the results on the choice of the renormalization scale is investigated. The combination of the results using matched predictions gives alpha_s(MZ)=0.1187+{0.0034}-{0.0019}. The strong coupling is also obtained, at lower precision, from O(alpha_s^2) fits of the c.m.s. energy evolution of some of the observables. A qualitative comparison is made between the data and a recent MLLA prediction for mean jet multiplicities.
description: 49 pages, 17 figures, submitted to Eur.Phys.J. C
Melittini Schenck 1860
Creators: name: Risch, Stephan
name: Roberts, Stuart P. M.
name: Smit, Jan
name: Wood, Thomas J.
name: Michez, Denis
name: Reverté, Sara
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Melittidae

description: Tribe Melittini Schenck, 1860    Genus Melitta Kirby, 1802
description: Published as part of Risch, Stephan, Roberts, Stuart P. M., Smit, Jan, Wood, Thomas J., Michez, Denis & Reverté, Sara, 2023, The new annotated checklist of the wild bees of Europe (Hymenoptera: Anthophila), pp. 1-147 in Zootaxa 5327 (1) on page 128, DOI: 10.11646/zootaxa.5327.1.1, http://zenodo.org/record/8244373
Definition of a Balancing Point for Electricity Transmission Contracts
Creators: name: Olmos, Luis
name: Neuhoff, Karsten
Publisher: name: Faculty of Economics
Year: 2004
Subjects: subject: Classification-JEL: D43, L94, L50
subject: Keywords: Transmission contract design, Congestion management, Market Power, European electricity network

description: Electricity transmission contracts allocate scarce resources, allow hedging against locational price differences and provide information to guide investment. Liquidity is increased if all transmission contracts are defined relative to one balancing point, then a set of two contracts can replicate any point to point contract. We propose an algorithm and apply it to the European electricity network to identify a well connected balancing point that exhibits minimal relative cross-price responses and hence reduces market power exercised by generation companies. Market level data which is difficult to obtain or model such as price levels in different regions or that is dependent on the time scale of interaction, as demand elasticity, is not required. The only critical input quantities are assumptions on future transmission constraint patterns.
Improved Ramsey-type results for comparability graphs
Creators: name: Korándi, Dániel
name: Tomon, István
Publisher: name: arXiv
Year: 2018
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Several discrete geometry problems are equivalent to estimating the size of the largest homogeneous sets in graphs that happen to be the union of few comparability graphs. An important observation for such results is that if $G$ is an $n$-vertex graph that is the union of $r$ comparability (or more generally, perfect) graphs, then either $G$ or its complement contains a clique of size $n^{1/(r+1)}$. This bound is known to be tight for $r=1$. The question whether it is optimal for $r\ge 2$ was studied by Dumitrescu and Tóth. We prove that it is essentially best possible for $r=2$, as well: we introduce a probabilistic construction of two comparability graphs on $n$ vertices, whose union contains no clique or independent set of size $n^{1/3+o(1)}$. Using similar ideas, we can also construct a graph $G$ that is the union of $r$ comparability graphs, and neither $G$, nor its complement contains a complete bipartite graph with parts of size $\frac{cn}{(\log n)^r}$. With this, we improve a result of Fox and Pach.
description: 11 pages, 1 figure
Additional file 5: of Biological clock function is linked to proactive and reactive personality types
Creators: name: Tudorache, Christian
name: Slabbekoorn, Hans
name: Robbers, Yuri
name: Hin, Eline
name: Meijer, Johanna
name: Spaink, Herman
name: Schaaf, Marcel
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Figure S4. Correlation between the concentration of cortisol and melatonin and emergence rank. The areas under the curve (AUC) and the amplitude were calculated for whole body cortisol and melatonin concentrations over time and plotted against emergence rank 1â 10. The results show significant positive correlations of the AUC (A, B) and negative correlations for the amplitude (C, D) values for both, cortisol (A, B) and melatonin (C, D) (Spearman rank, significance accepted at pâ
The elastic QCD dipole amplitude at one-loop
Creators: name: Navelet, H.
name: Peschanski, R.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We derive the analytic expression of the two one-loop dipole contributions to the elastic 4-gluon amplitude in QCD. The first one corresponds to the double QCD pomeron exchange, the other to an order alpha^2 correction to one-pomeron exchange. Both are expressed in terms of the square of the recently derived triple QCD pomeron vertex and involve a summation over all conformal Eigenvectors of the BFKL kernel.
description: 6 pages, REVTEX file + 2 .eps figures
Advances in the accuracy, stability, and reliability of the PTB primary fountain clocks
Creators: name: Weyers, S.
name: Gerginov, V.
name: Kazda, M.
name: Rahm, J.
name: Lipphardt, B.
name: Dobrev, G.
name: Gibble, K.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Improvements of the systematic uncertainty, frequency instability, and long-term reliability of the two caesium fountain primary frequency standards CSF1 and CSF2 at PTB (Physikalisch-Technische Bundesanstalt) are described. We have further investigated many of the systematic effects and made a number of modifications of the fountains. With an optically stabilized microwave oscillator, the quantum projection noise limited frequency instabilities are improved to $7.2 \times 10^{-14} (τ/1\,\mathrm{s})^{-1/2}$ for CSF1 and $2.5 \times 10^{-14} (τ/1\,\mathrm{s})^{-1/2}$ for CSF2 at high atom density. The systematic uncertainties of CSF1 and CSF2 are reduced to $2.74 \times 10^{-16}$ and $1.71 \times 10^{-16}$, respectively. Both fountain clocks regularly calibrate the scale unit of International Atomic Time (TAI) and the local realization of Coordinated Universal Time, UTC(PTB), and serve as references to measure the frequencies of local and remote optical frequency standards.
description: 33 pages, 7 figures
Physics of hot and dense QCD
Creators: name: Smilga, A. V.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We give a brief review of modern theoretical understanding of the physics of QCD at finite temperature and density. We concentrate in particular on the properties of hadron gas at relatively small temperatures and discuss in details the physics of the phase transition. We argue that the phase transition in temperature is probably absent, but it can appear with a vengeance when finite density effects are taken into account. We notice also that the temperatures one can expect to reach at the heavy ion collider at RHIC are not yet high enough for the perturbation theory in the QCD coupling constant to work well.
description: 19 pages, 6 Postscript figures. Invited talk at the International Nuclear Physics Conference, Paris, 1998, to be published in the proceedings
Features of the rare pathogen Meyerozyma guilliermondii strain SO and comprehensive in silico analyses of its adherence-contributing virulence factor agglutinin-like sequences
Creators: name: Lim, Si Jie
name: Noor, Noor Dina Muhd
name: Sabri, Suriana
name: Ali, Mohd Shukuri Mohamad
name: Salleh, Abu Bakar
name: Oslan, Siti Nurbaya
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Virology

description: Meyerozyma guilliermondii is a rare yeast pathogen contributing to the deadly invasive candidiasis. M. guilliermondii strain SO, as a promising protein expression host, showed 99% proteome similarity with the clinically isolated ATCC 6260 (type strain) in a recent comparative genomic analysis. However, their in vitro virulence features and in vivo pathogenicity were uncharacterized. This study aimed to characterize the in vitro and in vivo pathogenicity of M. guilliermondii strain SO and analyze its Als proteins (MgAls) via comprehensive bioinformatics approaches. M. guilliermondii strain SO showed lower and higher sensitivity towards β-mercaptoethanol and lithium, respectively than the avirulent S. cerevisiae but exhibited the same tolerance towards cell wall-perturbing Congo Red with C. albicans. With 7.5× higher biofilm mass, M. guilliermondii strain SO also demonstrated 75% higher mortality rate in the zebrafish embryos with a thicker biofilm layer on the chorion compared to the avirulent S. cerevisiae. Being one of the most important Candida adhesins, sequence and structural analyses of four statistically identified MgAls showed that MgAls1056 was predicted to exhibit the most conserved amyloid-forming regions, tandem repeat domain and peptide binding cavity (PBC) compared to C. albicans Als3. Favoured from the predicted largest ligand binding site and druggable pockets, it showed the highest affinity towards hepta-threonine. Non-PBC druggable pockets in the most potent virulence contributing MgAls1056 provide new insights into developing antifungal drugs targeting non-albicans Candida spp. Virtual screening of available synthetic or natural bioactive compounds and MgAls1056 deletion from the fungal genome should be further performed and validated experimentally.
Infra-Red Stable Supersymmetry in Chern-Simons Theories with Matter and Quenched Disorder
Creators: name: Hamidian, H.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study Abelian Chern-Simons field theories with matter fields and global SU(N) symmetry in the presence of random weak quenched disorder. In the absence of disorder these theories possess N=2 supersymmetric fixed points and N=1 supersymmetric fixed lines in the infra-red limit. We show that although the presence of disorder forbids any supersymmetry of the bare action, infra-red stable supersymmetric fixed points and fixed lines are realized in the disorder-averaged effective theories.
description: 8 pp., LaTeX. Explanatory remarks and references added. Version to appear in Phys. Rev. Lett
Additional file 5 of Construction and validation of a prognostic model of RNA binding proteins in clear cell renal carcinoma
Creators: name: Han, Wenkai
name: Fan, Bohao
name: Huang, Yongsheng
name: Wang, Xiongbao
name: Zhang, Zhao
name: Gu, Gangli
name: Liu, Zhao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Additional file 5. RNA extraction from tissues.
BCS-Universal Ratios within the Van Hove Scenario
Creators: name: Baquero, R.
name: Quesada, D.
name: Trallero-Giner, C.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: The central result of BCS theory are the Universal Ratios which do not depend on physical parameters of the superconductor under study. Several attempts have been made to introduce the van Hove Scenario within BCS theory but in none of them the Universal Ratios of conventional superconductivity appear to be a number independent of parameters. This fact prevents the precise definition of a deviation from the BCS value for a particular superconductor. This concept is at the basis of several applications of BCS theory in characterizing conventional superconductors. We define a system that constitutes a weak coupling limit that retains the essential features of the high-Tc oxides and which does not differ in any essential way from other models widely used in generalizations of BCS theory to high-Tc superconductors. The difference is that we found a natural way of dealing with the mathematics of the problem so as to get Universal Ratios in the same sense as in conventional superconductivity.
description: 11 PAGES, NO FIGURES, REVTEX 3.0
One-loop effects of MSSM particles in e^-e^+ \to Zh and e^-e^+ \to ν\barνh at the ILC
Creators: name: Kouda, Yusaku
name: Kon, Tadashi
name: Kurihara, Yoshimasa
name: Ishikawa, Tadashi
name: Jimbo, Masato
name: Kato, Kiyoshi
name: Kuroda, Masaaki
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The 1-loop effects of the MSSM at the ILC are investigated through numerical analysis. We studied the higgs production processes $e^-e^+\rightarrow Zh$ and $e^-e^+\rightarrow ν\barνh$ at the ILC. It is found that the magnitude of the MSSM contribution through the 1-loop effects is sizable enough to be detected. In the study, three sets of the MSSM parameters are proposed, which are consistent with the observed higgs mass, the muon $g$-$2$, the dark matter abundance and the decay branching ratios of $B$ mesons. In the $e^-e^+\rightarrow Zh$ process, the 1-loop effects of the MSSM are visible and the distinction of the parameter sets is partially possible. For the study of $e^-e^+\rightarrow ν\barνh$, we used the equivalent $\it W$-boson approximation in the evaluation of the 1-loop cross section. While the 1-loop effect of the MSSM is visible, the distinction of the parameter sets might not be possible in this process under the value of realistic luminosity at the ILC.
In silico and in vitro evaluation of newly synthesized pyrazolo-pyridine fused tetrazolo-pyrimidines derivatives as potential anticancer and antimicrobial agents
Creators: name: Patel, Harsh C.
name: Patel, Manan S.
name: Parekh, Jaydeepkumar N.
name: Chudasama, Dipakkumar D.
name: Dalwadi, Priyanka
name: Kunjadiya, Anju
name: Bhatt, Vaibhav
name: Modi, Krunal M.
name: Patel, Chirag N.
name: Ram, Kesur R.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Diversely functionalized pyrazolo-pyridine fused tetrazolo-pyrimidines 10aa-am and 10ba-bn were successfully synthesized via a catalyst-free synthetic protocol with moderate to very good yields. The compounds were evaluated for cytotoxicity against MCF-7 and HEK-293 cells using MTT assay. Among the tested compounds, 10ab (IC50- 23.83 µM) and 10ah (IC50- 23.30 µM) demonstrated the highest potency against MCF-7 cells, while 10bc (IC50- 14.46 µM) and 10bh (IC50- 2.53 µM) exhibited excellent cytotoxicity against HEK-293 cells. Additionally, antibacterial screening was performed against three Gram-negative bacteria (E. coli, P. aeruginosa, and S. enterica) and three Gram-positive bacteria (S. aureus, B. megaterium, and B. subtilis) using broth dilution method, while antifungal activity was assessed against three fungal strains (A. niger, Penicillium, and S. cerevisiae) using agar well diffusion method. In antimicrobial screening, the majority of the compounds demonstrated significant antibacterial efficacy compared to antifungal activity. We also conducted comprehensive computational studies, including DFT calculations, molecular docking and dynamics, and drug-likeness assessments. In the DFT study, compounds 10ac and 10bc displayed stable conformations, indicating their potential for higher therapeutic activity. Molecular docking analyses revealed compelling interactions, with compound 10ah demonstrating docking score −7.42 kcal/mol against catalytical domain PARP1 (PDB ID: 7KK4) and 10bh exhibiting a best docking score −10.77 kcal/mol against human corticotropin-releasing factor receptor 1 (PDB ID: 4Z9G). A 100 ns molecular dynamics (MD) simulation study of compounds 10ah and 10bh revealed the stable conformation and binding energy in a stimulating environment. In drug-likeness assessments, both the compounds 10ah and 10bh adhere all the established guidelines.
MOESM2 of A machine vision platform for measuring imbibition of maize kernels: quantification of genetic effects and correlations with germination
Creators: name: Miller, Nathan
name: Stelpflug, Scott
name: Kaeppler, Shawn
name: Spalding, Edgar
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: Additional file 2. Genotypes selected to evaluate the relationship between k and germination. Table of genotype, swelling category, swelling coefficient, and germination metrics