cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Pure subrings of regular local rings, endomorphism rings and Frobenius morphisms
Creators: name: Yasuda, Takehiko
Publisher: name: arXiv
Year: 2011
Subjects: subject: Rings and Algebras (math.RA)
subject: Commutative Algebra (math.AC)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 16E10, 16S50, 16S35, 14A22, 14E15, 14G17, 13A35, 13A50

description: The aim of this paper is threefold: first, to prove that the endomorphism ring associated to a pure subring of a regular local ring is a noncommutative crepant resolution if it is maximal Cohen-Macaulay; second, to see that in that situation, a different, but Morita equivalent, noncommutative crepant resolution can be constructed by using Frobenius morphisms; finally, to study the relation between Frobenius morphisms of noncommutative rings and the finiteness of global dimension. As a byproduct, we will obtain a result on wild quotient singularities: If the smooth cover of a wild quotient singularity is unramified in codimension one, then the singularity is not strongly F-regular.
description: 16 pages
Melting Pattern of Diquark Condensates in Quark Matter
Creators: name: Iida, K.
name: Matsuura, T.
name: Tachibana, M.
name: Hatsuda, T.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Thermal color superconducting phase transitions in high density three-flavor quark matter are investigated in the Ginzburg-Landau approach. Effects of nonzero strange quark mass, electric and color charge neutrality, and direct instantons are considered. Weak coupling calculations show that an interplay between the mass and electric neutrality effects near the critical temperature gives rise to three successive second-order phase transitions as the temperature increases: a modified color-flavor locked (mCFL) phase (ud, ds, and us pairings) -> a ``dSC'' phase (ud and ds pairings) -> an isoscalar pairing phase (ud pairing) -> a normal phase (no pairing). The dSC phase is novel in the sense that while all eight gluons are massive as in the mCFL phase, three out of nine quark quasiparticles are gapless.
description: minor changes in the text, fig.2 modified
Leptophilic dark matter in gauged $U(1)_{L_e-L_μ}$ model in light of DAMPE cosmic ray $e^+ + e^-$ excess
Creators: name: Duan, Guang Hua
name: He, Xiao-Gang
name: Wu, Lei
name: Yang, Jin Min
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Motivated by the very recent cosmic-ray electron+positron excess observed by DAMPE collaboration, we investigate a Dirac fermion dark matter (DM) in the gauged $L_e - L_μ$ model. DM interacts with the electron and muon via the $U(1)_{e-μ}$ gauge boson $Z^{'}$. The model can explain the DAMPE data well. Although a non-zero DM-nucleon cross section is only generated at one loop level and there is a partial cancellation between $Z^{'}ee$ and $Z^{'}μμ$ couplings, we find that a large portion of $Z^{'}$ mass is ruled out from direct DM detection limit leaving the allowed $Z^{'}$ mass to be close to two times of the DM mass. Implications for $pp \to Z^{'} \to 2\ell$ and $pp \to 2\ell + Z^{'}$ , and muon $g-2$ anomaly are also studied.
description: Discussions added, version accepted by EPJC
Lifting automorphisms along abelian regular coverings of graphs
Creators: name: Chen, Haimiao
Publisher: name: arXiv
Year: 2011
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C10, 05C25

description: This article proposes an effective criterion for lifting automorphisms along regular coverings of graphs, with the covering transformation group being any finite abelian group.
description: 10 pages
Membrane tethering by the atlastin GTPase depends on GTP hydrolysis but not on forming the crossover configuration.
Creators: name: Simran G  Saini
name: Liu, Chuang
name: Peijun  Zhang
name: Lee, Christina
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The membrane-anchored atlastin GTPase couples nucleotide hydrolysis to the catalysis of homotypic membrane fusion to form a branched ER network. Trans dimerization between atlastins anchored in opposing membranes, accompanied by a crossover conformational change, is thought to draw the membranes together for fusion. Previous studies on the conformational coupling of atlastin to its GTP hydrolysis cycle have been carried out largely on atlastins lacking a membrane anchor. Consequently, whether fusion involves a discrete tethering step, and if so, the potential role of GTP hydrolysis and crossover in tethering remain unknown. Here, we used membrane-anchored atlastins in assays that separate tethering from fusion to dissect the requirements for each. We found that tethering depended on GTP hydrolysis; but, unlike fusion, it did not depend on crossover. Thus, GTP hydrolysis initiates stable head domain contact in trans to tether opposing membranes, whereas crossover formation plays a more pivotal role in powering the lipid rearrangements for fusion.
title: ADCO, Ordre cistercien : comptes (1403-1423) (11 H 1161), f. 00051
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP

description: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161), f. 00051, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
Stability of FD-TD schemes for Maxwell-Debye and Maxwell-Lorentz equations
Creators: name: Bidégaray-Fesquet, Brigitte
Publisher: name: arXiv
Year: 2005
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65M12, 78M20

description: The stability of five finite difference-time domain (FD-TD) schemes coupling Maxwell equations to Debye or Lorentz models have been analyzed in [1] (P.G. Petropoulos, "Stability and phase error analysis of FD-TD in dispersive dielectrics", IEEE Transactions on Antennas and Propagation, vol. 42, no. 1, pp. 62--69, 1994), where numerical evidence for specific media have been used. We use von Neumann analysis to give necessary and sufficient stability conditions for these schemes for any medium, in accordance with the partial results of [1].
Lobelia comosa Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia comosa

description: Lobelia comosa Linnaeus, Species Plantarum 2: 933. 1753.
"Habitat in Aethiopia." RCN: 6746.
Type not designated.
Original material: none traced.
 Current name: Lobelia comosa L. (Campanulaceae).
 Note: Although Adamson (in J. S. African Bot. 8: 274. 1942) stated that this was based on the Hortus Cliffortianus account, there are no Clifford collections now associated with this name.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on pages 637-638, DOI: 10.5281/zenodo.291971
Mechanisms and benefits of granule cell latency coding in the mouse olfactory bulb.
Creators: name: Giridhar, Sonya
name: Urban, Nathan
Publisher: name: Carnegie Mellon University
Year: 2012
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Inhibitory circuits are critical for shaping odor representations in the olfactory bulb. There, individual granule cells can respond to brief stimulation with extremely long (up to 1000 ms), input-specific latencies that are highly reliable. However, the mechanism and function of this long timescale activity remain unknown. We sought to elucidate the mechanism responsible for long-latency activity, and to understand the impact of widely distributed interneuron latencies on olfactory coding. We used a combination of electrophysiological, optical, and pharmacological techniques to show that long-latency inhibition is driven by late onset synaptic excitation to granule cells. This late excitation originates from tufted cells, which have intrinsic properties that favor longer latency spiking than mitral cells. Using computational modeling, we show that widely distributed interneuron latency increases the discriminability of similar stimuli. Thus, long-latency inhibition in the olfactory bulb requires a combination of circuit- and cellular-level mechanisms that function to improve stimulus representations.
Maturation of GABAergic inhibition promotes strengthening of temporally coherent inputs among convergent pathways.
Creators: name: Kuhlman, Sandra
name: Jiangteng  Lu
name: Lazarus, Matthew S.
name: Z. Josh  Huang
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Spike-timing-dependent plasticity (STDP), a form of Hebbian plasticity, is inherently stabilizing. Whether and how GABAergic inhibition influences STDP is not well understood. Using a model neuron driven by converging inputs modifiable by STDP, we determined that a sufficient level of inhibition was critical to ensure that temporal coherence (correlation among presynaptic spike times) of synaptic inputs, rather than initial strength or number of inputs within a pathway, controlled postsynaptic spike timing. Inhibition exerted this effect by preferentially reducing synaptic efficacy, the ability of inputs to evoke postsynaptic action potentials, of the less coherent inputs. In visual cortical slices, inhibition potently reduced synaptic efficacy at ages during but not before the critical period of ocular dominance (OD) plasticity. Whole-cell recordings revealed that the amplitude of unitary IPSCs from parvalbumin positive (Pv+) interneurons to pyramidal neurons increased during the critical period, while the synaptic decay time-constant decreased. In addition, intrinsic properties of Pv+ interneurons matured, resulting in an increase in instantaneous firing rate. Our results suggest that maturation of inhibition in visual cortex ensures that the temporally coherent inputs (e.g. those from the open eye during monocular deprivation) control postsynaptic spike times of binocular neurons, a prerequisite for Hebbian mechanisms to induce OD plasticity.
Mapping stain distribution in pathology slides using whole slide imaging.
Creators: name: Fang-Cheng  Yeh
name: Ye, Qing
name: T. Kevin  Hitchens
name: Yi-Jen L. Wu
name: Parwani, Anil V.
name: Ho, Chien
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: BACKGROUND: Whole slide imaging (WSI) offers a novel approach to digitize and review pathology slides, but the voluminous data generated by this technology demand new computational methods for image analysis. MATERIALS AND METHODS: In this study, we report a method that recognizes stains in WSI data and uses kernel density estimator to calculate the stain density across the digitized pathology slides. The validation study was conducted using a rat model of acute cardiac allograft rejection and another rat model of heart ischemia/reperfusion injury. Immunohistochemistry (IHC) was conducted to label ED1(+) macrophages in the tissue sections and the stained slides were digitized by a whole slide scanner. The whole slide images were tessellated to enable parallel processing. Pixel-wise stain classification was conducted to classify the IHC stains from those of the background and the density distribution of the identified IHC stains was then calculated by the kernel density estimator. RESULTS: The regression analysis showed a correlation coefficient of 0.8961 between the number of IHC stains counted by our stain recognition algorithm and that by the manual counting, suggesting that our stain recognition algorithm was in good agreement with the manual counting. The density distribution of the IHC stains showed a consistent pattern with those of the cellular magnetic resonance (MR) images that detected macrophages labeled by ultrasmall superparamagnetic iron-oxide or micron-sized iron-oxide particles. CONCLUSIONS: Our method provides a new imaging modality to facilitate clinical diagnosis. It also provides a way to validate/correlate cellular MRI data used for tracking immune-cell infiltration in cardiac transplant rejection and cardiac ischemic injury.
title: Identification of correlation between 3D surfaces using data mining techniques: a case study of predicting springback in sheet metal forming
Creators: name: El Salhi, S
Publisher: name: University of Liverpool Repository
Year: 2015

description: This thesis presents data mining research work undertaken in the context of identifying correlations between 3D surfaces. More specifically, this research is directed at predicting distortions (referred to as springback) in sheet metal forming. The main objective was to identify a mechanism that "best" serves to both capture effectively 3D geometrical information while at the same time allowing for the generation of effective predictors (classifiers). To this end, three distinct 3D surface representation techniques are proposed based on three different concepts. The first technique, the Local Geometry Matrices (LGM) representation, is founded on the idea of Local Binary Patterns (LBPs), as used with respect to image texture analysis, whereby surfaces are defined in terms of local neighbourhoods surrounding individual points in a 3D surface. The second technique, the Local Distance Measure (LDM) representation, is influenced by the observation that springback is greater further from edges and corners, consequently surfaces are defined in terms of distance to the nearest edge or corner. The third technique, the Point Series (PS) representation, is founded on the idea of using a spatial "linearisation" with which to represent surfaces in terms of point series curves. The thesis describes and discusses each of these in detail including, in each case, the theoretical underpinning supporting each representation. A full evaluation of each of the representations is also presented. As will become apparent, the PS technique was found to be the most effective. The presented evaluation was directed at predicting springback, in the context of the Asymmetric Incremental Sheet Forming (AISF) manufacturing process, in such a way that an enhanced version of the desired 3D surface can be proposed intended to minimise the effect of springback. For the evaluation two at-topped, square-based, pyramid shapes were used. Each pyramid had been manufactured twice using Steel and twice using Titanium. In addition this thesis presents some idea on how the springback prediction mechanism can be incorporated into an "intelligent process model". The evaluation of this model, by manufacturing corrected shapes, established that a sound prediction framework, incorporating the 3D surface representation techniques espoused in this thesis coupled with a compatible classification technique, had been established.
Manganese-induced trafficking and turnover of the cis-Golgi glycoprotein GPP130.
Creators: name: Somshuvra  Mukhopadhyay
name: Bachert, Collin
name: Smith, Donald R.
name: Linstedt, Adam
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Manganese is an essential element that is also neurotoxic at elevated exposure. However, mechanisms regulating Mn homeostasis in mammalian cells are largely unknown. Because increases in cytosolic Mn induce rapid changes in the localization of proteins involved in regulating intracellular Mn concentrations in yeast, we were intrigued to discover that low concentrations of extracellular Mn induced rapid redistribution of the mammalian cis-Golgi glycoprotein Golgi phosphoprotein of 130 kDa (GPP130) to multivesicular bodies. GPP130 was subsequently degraded in lysosomes. The Mn-induced trafficking of GPP130 occurred from the Golgi via a Rab-7-dependent pathway and did not require its transit through the plasma membrane or early endosomes. Although the cytoplasmic domain of GPP130 was dispensable for its ability to respond to Mn, its lumenal stem domain was required and it had to be targeted to the cis-Golgi for the Mn response to occur. Remarkably, the stem domain was sufficient to confer Mn sensitivity to another cis-Golgi protein. Our results identify the stem domain of GPP130 as a novel Mn sensor in the Golgi lumen of mammalian cells.
Assessing the collision nature of coronal mass ejections in the inner heliosphere
Creators: name: Mishra, Wageesh
name: Wang, Yuming
name: Srivastava, Nandita
name: Shen, Chenglong
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: There have been few attempts in the past to understand the collision of individual cases of interacting Coronal Mass Ejections (CMEs). We selected 8 cases of interacting CMEs and estimated their propagation and expansion speeds, direction of impact and masses exploiting coronagraphic and heliospheric imaging observations. Using these estimates with ignoring the errors therein, we find that the nature of collision is perfectly inelastic for 2 cases (e.g., 2012 March and November), inelastic for 2 cases (e.g., 2012 June and 2011 August), elastic for 1 case (e.g., 2013 October) and super-elastic for 3 cases (e.g., 2011 February, 2010 May and 2012 September). Admitting large uncertainties in the estimated directions, angular widths and pre-collision speeds; the probability of perfectly inelastic collision for 2012 March and November cases diverge from 98%-60% and 100%-40%, respectively, reserving some probability for other nature of collision. Similarly, the probability of inelastic collision diverge from 95%-50% for 2012 June case, 85%-50% for 2011 August case, and 75%-15% for 2013 October case. We note that probability of super-elastic collision for 2011 February, 2010 May and 2012 September CMEs diverge from 90%-75%, 60%-45% and 90%-50%, respectively. Although the sample size is small, we find a good dependence of nature of collision on CMEs parameters. The crucial pre-collision parameters of the CMEs responsible for increasing the probability of super-elastic collision, in descending order of priority, are their lower approaching speed, higher expansion speed of the following CME over the preceding one, and longer duration of collision phase.
description: 38 pages, 13 figures, accepted in ApJ Supplement Series
Centropogon cornutus Druce
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Centropogon
Centropogon cornutus

description: Lobelia cornuta Linnaeus, Species Plantarum 2: 930. 1753.
"Habitat in Cayenna." RCN: 6743.
Type not designated.
Original material: none traced.
 Current name: Centropogon cornutus (L.) Druce (Campanulaceae).
 Note: Although Staples (in Howard, Fl. Lesser Antilles 6: 498. 1989) stated "Type: Cayenne, Royen, n. v.", the statement is derived from the protologue and does not imply the existence of a specific D. van Royen collection.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 638, DOI: 10.5281/zenodo.291971
Satellite Remote Sensing of Chlorophyll-a inSubalpine Italian Lakes in the last 15 Years
Creators: name: Bresciani, Mariano
name: Giardino, Claudia
name: Stroppiana, Daniela
name: Cazzaniga, Ilaria
Publisher: name: Zenodo
Year: 2018

description: Poster at ells-iaglr-2018 Subalpine Lakes constitute an environment for ecosystem (flora and fauna),tourism,bathing, intake of drinking water, and agriculture. Due to the increasing demand for freshwater,the effect of climate change and the anthropogenic pressure on natural resources, their water quality is in danger. Therefore, there is an increasing need for regular long term monitoring of lake waters as well as to support national and international directives and conventions such as the European Water Framework Directive (WFD).Within this study, Earth Observation (EO) data are used for acquiring timely, frequent synoptic information of main Subalpine lakes in norther Italy with a focus on chlorophyll-a(Chl-a).
The Spiral Host Galaxy of the Double Radio Source 0313-192
Creators: name: Keel, William C.
name: White, Raymond E.
name: Owen, Frazer N.
name: Ledlow, Michael J.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present new Hubble, Gemini-S, and Chandra observations of the radio galaxy 0313-192, which hosts a 350-kpc double source and jets, even though previous data have suggested that it is a spiral galaxy. We measure the bulge scale and luminosity, radial and vertical profiles of disk starlight, and consider the distributions of H II regions and absorbing dust. In each case, the HST data confirm its classification as an edge-on spiral galaxy, the only such system known to produce such an extended radio source of this kind. The Gemini near-IR images and Chandra spectral fit reveal a strongly obscured central AGN, seen through the entire ISM path length of the disk and showing X-ray evidence of additional absorption from warm or dense material close to the central object. We consider several possible mechanisms for producing such a rare combination of AGN and host properties, some combination of which may be at work. These include an unusually luminous bulge (suggesting a black hole of mass 0.5-0.9 billion solar masses), orientation of the jets near the pole of the gas-rich disk, and some evidence of a weak gravitational interaction which has warped the disk and could have enhanced fuelling of the central engine. An X-ray counterpart of the kiloparsec-scale radio jet emerges to the south; jet/counterjet limits in both radio and X-ray allow them to be symmetric if seen more than 15 degrees from the plane of the sky, still consistent with the jet axes being within ~30 degrees of the poles of the gas-rich galaxy disk. A linear or disklike emission-line structure is seen around thenucleus, inclined by ~20 degrees to the stellar disk but nearly perpendicular to the jets; this may represent the aftermath of a galaxy encounter, where gas is photoionized by the nuclear continuum.
description: In press, Astron. J. 9 figures; 8 in shrunk JPEG form. Supported by NASA through STScI grant HST-GO-09376.01 and Chandra grant GO4-5118X
Manganese induces oligomerization to promote down-regulation of the intracellular trafficking receptor used by Shiga toxin.
Creators: name: Ritika  Tewari
name: Jarvela, Timothy S.
name: Linstedt, Adam
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Manganese (Mn) protects cells against lethal doses of purified Shiga toxin by causing the degradation of the cycling transmembrane protein GPP130, which the toxin uses as a trafficking receptor. Mn-induced GPP130 down-regulation, in addition to being a potential therapeutic approach against Shiga toxicosis, is a model for the study of metal regulated protein sorting. Significantly, however, the mechanism by which Mn regulates GPP130 trafficking is unknown. Here we show that a transferable trafficking determinant within GPP130 bound Mn and that Mn binding induced GPP130 oligomerization in the Golgi. Alanine substitutions blocking Mn binding abrogated both oligomerization of GPP130 and GPP130 sorting from the Golgi to lysosomes. Further, oligomerization was sufficient because forced aggregation, using a drug-controlled polymerization domain, redirected GPP130 to lysosomes in the absence of Mn. These experiments reveal metal-induced oligomerization as a Golgi sorting mechanism for a clinically relevant receptor for Shiga toxin.
The $p$-cyclic McKay correspondence via motivic integration
Creators: name: Yasuda, Takehiko
Publisher: name: arXiv
Year: 2012
Subjects: subject: Algebraic Geometry (math.AG)
subject: Commutative Algebra (math.AC)
subject: Number Theory (math.NT)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 14E16, 14E18, 13A50, 11S15, 20C20

description: We study the McKay correspondence for representations of the cyclic group of order $p$ in characteristic $p$. The main tool is the motivic integration generalized to quotient stacks associated to representations. Our version of the change of variables formula leads to an explicit computation of the stringy invariant of the quotient variety. A consequence is that a crepant resolution of the quotient variety (if any) has topological Euler characteristic $p$ like in the tame case. Also, we link a crepant resolution with a count of Artin-Schreier extensions of the power series field with respect to weights determined by ramification jumps and the representation.
description: 44 pages, v3: The term "strongly Kawamata log terminal" has been changed to "stringily Kawamata log terminal," as it is more consistent with the definition
Phenomenological implications of two simple modifications to Tri-Bimaximal mixing
Creators: name: Channey, Kanwaljeet S.
name: Kumar, Sanjeev
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the phenomenological implications of breaking the Tri-Bimaximal (TBM) mixing in such a way that either first or second column of TBM mixing matrix remains invariant. We present two such textures and confront them with the experimental data. We give the predictions of these textures for atmospheric mixing angle $θ_{23}$ and Dirac-type CP violating phase $δ$ that will be measured in the future experiments.
description: 10 pages, 5 figures
Manganese blocks intracellular trafficking of Shiga toxin and protects against Shiga toxicosis.
Creators: name: Somshuvra  Mukhopadhyay
name: Linstedt, Adam
Publisher: name: Carnegie Mellon University
Year: 2012
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Infections with Shiga toxin (STx)-producing bacteria cause more than a million deaths each year and have no definitive treatment. To exert its cytotoxic effect, STx invades cells through retrograde membrane trafficking, escaping the lysosomal degradative pathway. We found that the widely available metal manganese (Mn(2+)) blocked endosome-to-Golgi trafficking of STx and caused its degradation in lysosomes. Mn(2+) targeted the cycling Golgi protein GPP130, which STx bound in control cells during sorting into Golgi-directed endosomal tubules that bypass lysosomes. In tissue culture cells, treatment with Mn(2+) yielded a protection factor of 3800 against STx-induced cell death. Furthermore, mice injected with nontoxic doses of Mn(2+) were completely resistant to a lethal STx challenge. Thus, Mn(2+) may represent a low-cost therapeutic agent for the treatment of STx infections.
Functional renormalization with fermions and tetrads
Creators: name: Donà, Pietro
name: Percacci, Roberto
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate some aspects of the renormalization group flow of gravity in the presence of fermions, which have remained somewhat puzzling so far. The first is the sign of the fermionic contribution to the running of Newton's constant, which depends on details of the cutoff. We argue that only one of the previously used schemes correctly implements the cutoff on eigenvalues of the Dirac operator, and it acts in the sense of screening Newton's constant. We also show that Kähler fermions give the same contribution to the running of the cosmological and Newton constant as four Dirac spinors. We then calculate the graviton contributions to the beta functions by imposing the cutoffs on the irreducible spin components of the tetrad. In this way we can probe the gauge dependence of the off-shell flow. The results resemble closely those of the metric formalism, except for an increased scheme-- and (off shell) gauge--dependence.
description: 28 pages, 4 figures
An adaptive variational procedure for the conservative and positivity preserving Allen-Cahn phase-field model
Creators: name: Joshi, Vaibhav
name: Jaiman, Rajeev K.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We present an adaptive variational procedure for unstructured meshes to capture fluid-fluid interfaces in two-phase flows. The two phases are modeled by the phase-field finite element formulation, which involves the conservative Allen-Cahn equation coupled with the incompressible Navier-Stokes equations. The positivity preserving variational formulation is designed to maintain the bounded and stable solution of the Allen-Cahn equation. For the adaptivity procedure, we consider the residual-based error estimates for the underlying differential equations of the two-phase system. In particular, the adaptive refinement/coarsening is carried out by the newest vertex bisection algorithm by evaluating the residual error indicators based on the error estimates of the Allen-Cahn equation. The coarsening algorithm avoids the storage of the tree data structures for the hierarchical mesh, thus providing the ease of numerical implementation. The proposed nonlinear adaptive partitioned procedure aims at reducing the amount of coarsening while maintaining the convergence properties of the underlying nonlinear coupled differential equations. We investigate the adaptive phase-field finite element scheme through the spinodal decomposition in a complex curved geometry and the volume-conserved interface motion driven by the mean curvature flow for two circles in a square domain. We then assess the accuracy and efficiency of the proposed procedure by modeling the free-surface motion in a sloshing tank. The mesh adaptivity remarkably reduces the degrees of freedom and the computational cost by nearly half for similar accuracy and improves the mass conservation. Finally, we apply the adaptive numerical framework to solve the application of a dam-breaking problem with topological changes.
description: 33 pages, 20 figures, 1 table
Malachite green mediates homodimerization of antibody VL domains to form a fluorescent ternary complex with singular symmetric interfaces.
Creators: name: Szent-Gyorgyi, Christopher
name: Stanfield, Robyn L.
name: Andreko, Susan
name: Dempsey, Alison
name: Ahmed, Mushtaq
name: Capek, Sarah
name: Waggoner, Alan
name: Wilson, Ian A.
name: Bruchez, Marcel
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: We report that a symmetric small-molecule ligand mediates the assembly of antibody light chain variable domains (VLs) into a correspondent symmetric ternary complex with novel interfaces. The L5* fluorogen activating protein is a VL domain that binds malachite green (MG) dye to activate intense fluorescence. Crystallography of liganded L5* reveals a 2:1 protein:ligand complex with inclusive C2 symmetry, where MG is almost entirely encapsulated between an antiparallel arrangement of the two VL domains. Unliganded L5* VL domains crystallize as a similar antiparallel VL/VL homodimer. The complementarity-determining regions are spatially oriented to form novel VL/VL and VL/ligand interfaces that tightly constrain a propeller conformer of MG. Binding equilibrium analysis suggests highly cooperative assembly to form a very stable VL/MG/VL complex, such that MG behaves as a strong chemical inducer of dimerization. Fusion of two VL domains into a single protein tightens MG binding over 1000-fold to low picomolar affinity without altering the large binding enthalpy, suggesting that bonding interactions with ligand and restriction of domain movements make independent contributions to binding. Fluorescence activation of a symmetrical fluorogen provides a selection mechanism for the isolation and directed evolution of ternary complexes where unnatural symmetric binding interfaces are favored over canonical antibody interfaces. As exemplified by L5*, these self-reporting complexes may be useful as modulators of protein association or as high-affinity protein tags and capture reagents.
Lobelia coronopifolia Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Campanulaceae
Lobelia
Lobelia coronopifolia

description: Lobelia coronopifolia Linnaeus, Species Plantarum 2: 933. 1753.
"Habitat in Aethiopia." RCN: 6762.
Type not designated.
Original material: [icon] in Burman, Rar. Afric. Pl.: 98, t. 38, f. 1. 1738; [icon] in Breyn, Exot. Pl. Cent.: 174, t. 88. 1678.
 Current name: Lobelia coronopifolia L. (Campanulaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 638, DOI: 10.5281/zenodo.291971
Magnetophoresis of nanoparticles.
Creators: name: Jitkang  Lim
name: Lanni, Caitlin
name: Evarts, Eric R.
name: Lanni, Frederick
name: Tilton, Robert
name: Majetich, Sara A.
Publisher: name: Carnegie Mellon University
Year: 2011
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Iron oxide cores of 35 nm are coated with gold nanoparticles so that individual particle motion can be tracked in real time through the plasmonic response using dark field optical microscopy. Although Brownian and viscous drag forces are pronounced for nanoparticles, we show that magnetic manipulation is possible using large magnetic field gradients. The trajectories are analyzed to separate contributions from the different types of forces. With field gradients up to 3000 T/m, forces as small as 1.5 fN are detected.
Dirac and Chiral Quantum Spin Liquids on the Honeycomb Lattice in a Magnetic Field
Creators: name: Liu, Zheng-Xin
name: Normand, Bruce
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Motivated by recent experimental observations in $α$-RuCl$_3$, we study the $K$-$Γ$ model on the honeycomb lattice in an external magnetic field. By a slave-particle representation and Variational Monte Carlo calculations, we reproduce the phase transition from zigzag magnetic order to a field-induced disordered phase. The nature of this state depends crucially on the field orientation. For particular field directions in the honeycomb plane, we find a gapless Dirac spin liquid, in agreement with recent experiments on $α$-RuCl$_3$. For a range of out-of-plane fields, we predict the existence of a Kalmeyer-Laughlin-type chiral spin liquid, which would show an integer-quantized thermal Hall effect.
description: 5+9 pages, 4+6 figures
BEC for photons and neutral pions
Creators: name: Utyuzh, Oleg. V.
name: Wilk, Grzegorz
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The role of BEC for photons and neutral pions is briefly discussed and illustrated by means of new method of numerical modelling of BEC proposed by us recently.
description: Contribution to Second Warsaw Meeting on Particle Correlations and Resonances in Heavy Ion Collisions, Warsaw, 15-18 October, 2003, Poland
Enumerating typical abelian coverings of Cayley graphs
Creators: name: Chen, Haimiao
Publisher: name: arXiv
Year: 2012
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C10, 05C25

description: In this article we complete the work of enumerating typical abelian coverings of Cayley graphs, by reducing the problem to enumerating certain subgroups of finite abelian groups.
description: 15pages
Lifting graph automorphisms along solvable regular covers
Creators: name: Chen, Haimiao
name: Kwak, Jin Ho
Publisher: name: arXiv
Year: 2012
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 05C10, 05C25, 20B25

description: A {\em solvable} cover of a graph is a regular cover whose covering transformation group is solvable. In this paper, we show that a solvable cover of a graph can be decomposed into layers of abelian covers, and also, a lift of a given automorphism of the base graph of a solvable cover can be decomposed into layers of lifts of the automorphism in the layers of the abelian covers. This procedure is applied to classify metacyclic covers of the tetrahedron branched at face-centers.
description: 23 pages, 1 figures
The Energy Transfer Process in Planetary Flybys
Creators: name: Anderson, John D.
name: Campbell, James K.
name: Nieto, Michael Martin
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We illustrate the energy transfer during planetary flybys as a function of time using a number of flight mission examples. The energy transfer process is rather more complicated than a monotonic increase (or decrease) of energy with time. It exhibits temporary maxima and minima with time which then partially moderate before the asymptotic condition is obtained. The energy transfer to angular momentum is exhibited by an approximate Jacobi constant for the system. We demonstrate this with flybys that have shown unexplained behaviors: i) the possible onset of the "Pioneer anomaly" with the gravity assist of Pioneer 11 by Saturn to hyperbolic orbit (as well as the Pioneer 10 hyperbolic gravity assist by Jupiter) and ii) the Earth flyby anomalies of small increases in energy {\it in the geocentric system} (Galileo-I, NEAR, and Rosetta, in additioon discussing the Cassini and Messenger flybys). Perhaps some small, as yet unrecognized effect in the energy-transfer process can shed light on these anomalies.
description: 29 pages, 43 images combined into 13 figures. Additions to answer comments of referee
title: Don Carlos d'Aragon, prince de Viane : Etude sur l'Espagne du Nord au XVè siècle
Creators: name: Desdevizes du Dézert, Georges
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: XVI + 455 p.. : pl., carte
description: Source: Bibliothèque patrimoniale Villon (Rouen), fonds Leber, m 2455
Strong decays of $D_J(3000)$ and $D_{sJ}(3040)$
Creators: name: Li, Si-Chen
name: Wang, Tianhong
name: Jiang, Yue
name: Tan, Xiao-Ze
name: Li, Qiang
name: Wang, Guo-Li
name: Chang, Chao-Hsi
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper, we systematically calculate two-body strong decays of newly observed $D_J(3000)$ and $D_{sJ}(3040)$ with 2P$(1^+)$ and 2P$(1^{+\prime})$ assignments in an instantaneous approximation of the Bethe-Salpeter equation method. Our results show that both resonances can be explained as the 2P$(1^{+'})$ with broad width via $^3P_1$ and $^1P_1$ mixing in $D$ and $D_s$ families. For $D_J(3000)$, the total width is 229.6 MeV in our calculation, close to the upper limit of experimental data, and the dominant decay channels are $D_2^*π$, $D^*π$, and $D^*(2600)π$. For $D_{sJ}(3040)$, the total width is 157.4 MeV in our calculation, close to the lower limit of experimental data, and the dominant channels are $D^*K$ and $D^*K^*$. These results are consistent with observed channels in experiments. Given the very little information that has been obtained from experiments and the large error bars of the total decay widths, we recommend the detection of dominant channels in our calculation.
description: 22 pages, 2 figures
Magnetic resonance imaging investigation of macrophages in acute cardiac allograft rejection after heart transplantation.
Creators: name: Yi-Jen L. Wu
name: Ye, Qing
name: Eytan, Danielle F.
name: Liu, Li
name: Bedda L. Rosario
name: T. Kevin  Hitchens
name: Fang-Cheng  Yeh
name: Rooijen, Nico Van
name: Ho, Chien
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: BACKGROUND: Current immunosuppressive therapy after heart transplantation either generally suppresses the recipient's entire immune system or is mainly targeting T-lymphocytes. Monocytes/macrophages are recognized as a hallmark of acute allograft rejection, but the roles that they play are not well characterized in vivo, because the tools for accessing in situ macrophage infiltration are lacking. In this study, we used MRI to investigate the role of macrophages in acute heart allograft rejection by cellular and functional MRI with selectively depleted systemic macrophages without affecting other leukocyte population, as well as to explore the possibility that macrophages could be an alternative therapeutic target. METHODS AND RESULTS: A rodent heterotopic working heart-lung transplantation model was used for studying acute allograft rejection. Systemic macrophages were selectively depleted by treating recipient animals with clodronate-liposomes. Macrophage infiltration in the graft hearts was monitored by cellular MRI with in vivo ultrasmall superparamagnetic iron oxide particles labeling. Graft heart function was evaluated by tagging MRI followed by strain analysis. Clodronate-liposome treatment depletes circulating monocytes/macrophages in transplant recipients, and both cellular MRI and pathological examinations indicate a significant reduction in macrophage accumulation in the rejecting allograft hearts. In clodronate-liposome-treated group, allograft hearts exhibited preserved tissue integrity, partially reversed functional deterioration, and prolonged graft survival, compared with untreated controls. CONCLUSIONS: Cardiac cellular and functional MRI is a powerful tool to explore the roles of targeted immune cells in vivo. Our results indicate that macrophages are essential in acute cardiac allograft rejection, and selective depletion of macrophages with clodronate-liposomes protects hearts against allograft rejection, suggesting a potential therapeutic avenue. Our findings show that there is a finite risk of forming an intraventricular mass, presumably from the cellular debris or lipid material. Further optimization of the dosing protocol is necessary before clinical applications.
Risks of natural hazards and their consequence on environment.
Creators: name: Abdifatah, Ibrahim Gulled
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Risks of natural hazards and their consequence on environment
subject: Risks of natural hazards
subject: their consequence on environment
subject: Environment

description: Natural disasters are variations and extreme events which cause damage and destruction to human life safety, economic development, the living environment and resources. A natural hazard is a complex system with interactions between natural hazard-inducing factors (natural mutation factors) and the socio-economic system (the person property-environment-resource composite system) under certain conditions.

Every ten years the death tolls reach 1 million and more millions of people are rendered homeless. Destruction to the global economy caused by natural disasters was to USD40 billion in the 1960s, USD70 billion in the 1970s and up to USD120 billion in the 1980s .

Natural hazards regularly strike major cities in the world leading to numerous fatalities and billions of dollars of property and infrastructure damage each year. Recent examples include hurricane sandy which hit New York City and surrounding area in 2012, hurricane Harvey which caused severe flooding in Houston in 2017, each resulting in more than 100 deaths and Asian tsunami hit the coastal areas of the Indian Ocean bordering with Somalia. Climate scientists suggest that as global greenhouse gas emissions increase so too will the number and severity of natural disasters (IPCC 2012). Furthermore, as more economic activity clusters along ocean coasts, a greater share of population is now at risk of exposure to natural hazards (changnon et.al 2000:Rappaport & Sachs, 2013: pielke et al., 2008).
title: ADCO, Cartulaire de Cîteaux pour le prieuré de Gilly : rachat de la rente due à Saint-Germain-des-Prés (c. 1501), Cart. 194 (11 H 636), 64 folios, f. 0015
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour le prieuré de Gilly : rachat de la rente due à Saint-Germain-des-Prés (c. 1501), Archives départementales de la Côte-d'Or, Cart. 194 (11 H 636), 64 folios, f. 0015, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour le prieuré de Gilly : rachat de la rente due à Saint-Germain-des-Prés (c. 1501), Archives départementales de la Côte-d'Or, Cart. 194 (11 H 636), 64 folios, f. 0015, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Toward motivic integration over wild Deligne-Mumford stacks
Creators: name: Yasuda, Takehiko
Publisher: name: arXiv
Year: 2013
Subjects: subject: Algebraic Geometry (math.AG)
subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 14E18, 14E16, 11S15

description: We discuss how the motivic integration will be generalized to wild Deligne-Mumford stacks, that is, stabilizers may have order divisible by the characteristic of the base or residue field. We pose several conjectures on this topic. We also present some possible applications concerning stringy invariants, resolution of singularities, and weighted counts of extensions of local fields.
description: 24 pages; minor corrections, added footnotes to mention subsequent developments, to appear in the proceedings of the conference "Higher Dimensional Algebraic Geometry - in honour of Professor Yujiro Kawamata's sixtieth birthday" (ASPM)