title: ÐÑÐµÐ½ÐºÐ° ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐÐ¤Ð­ÐÐ¢/ÐÐ¢ ÑÐ¸ÑÑÐµÐ¼ Ð´Ð»Ñ Ac-225
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Sensitivity estimation for SPECT/CT systems for 225Ac
Creators: name: ÐÐ°ÑÐ¸Ð»ÑÐµÐ²Ð°, ÐÐ°Ð»ÐµÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½Ð°Ñ ÑÐµÑÐ°Ð¿Ð¸Ñ
ÑÐ°Ð´Ð¸Ð¾ÑÐ°ÑÐ¼Ð°ÑÐµÐ²ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð»ÐµÐºÐ°ÑÑÑÐ²ÐµÐ½Ð½ÑÐ¹ Ð¿ÑÐµÐ¿Ð°ÑÐ°Ñ
ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ ÐºÐ°ÑÐµÑÑÐ²Ð°
Ð¾Ð´Ð½Ð¾ÑÐ¾ÑÐ¾Ð½Ð½Ð°Ñ ÑÐ¼Ð¸ÑÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½Ð°Ñ ÑÐ¾Ð¼Ð¾Ð³ÑÐ°ÑÐ¸Ñ
ÐºÐ¾ÑÑÑÐ¸ÑÐ¸ÐµÐ½Ñ ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸
radionuclide therapy
radiopharmaceutical drugs
quality control
single photon emission computed tomography
sensitivity factor

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐµ ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐÐ¤Ð­ÐÐ¢/ÐÐ¢ ÑÐ¸ÑÑÐµÐ¼ Ð´Ð»Ñ 225Ac Ð¿ÑÐ¸ ÑÐ°Ð·Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼Ð°Ñ Ð´ÐµÑÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ, Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ°Ñ ÑÐ±Ð¾ÑÐ° Ð´Ð°Ð½Ð½ÑÑ Ð¸ Ð´Ð»Ñ ÑÐ°Ð·Ð½ÑÑ ÑÐµÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¹ Ð¸Ð·Ð¾Ð±ÑÐ°Ð¶ÐµÐ½Ð¸Ñ Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ ÑÑÐµÑ ÐÐ¤Ð­ÐÐ¢/ÐÐ¢-Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ¾Ð². Ð Ð°Ð±Ð¾ÑÐ° Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð»Ð°ÑÑ Ð½Ð° Ð±Ð°Ð·Ðµ Ð¤ÐÐÐ£ Â«ÐÐÐÐ¦ Ð¾Ð½ÐºÐ¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¸Ð¼. Ð¿ÑÐ¾Ñ. Ð.Ð. ÐÐµÑÑÐ¾Ð²Ð°Â» Ð¸ Ð¤ÐÐÐ£ ÐÐ¦Ð­Ð Ð Ð¸Ð¼. Ð.Ð.ÐÐ¸ÐºÐ¸ÑÐ¾ÑÐ¾Ð²Ð° ÐÐ§Ð¡ Ð Ð¾ÑÑÐ¸Ð¸, Ð³Ð´Ðµ Ð½Ð° Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ°Ñ GE Discovery NM 630; Siemens Symbia T16 Ñ ÐºÐ¾Ð»Ð»Ð¸Ð¼Ð°ÑÐ¾ÑÐ¾Ð¼ MEGP; Siemens Symbia T16 ÐºÐ¾Ð»Ð»Ð¸Ð¼Ð°ÑÐ¾ÑÐ¾Ð¼ HEGP ÑÐºÐ°Ð½Ð¸ÑÐ¾Ð²Ð°Ð»ÑÑ ÑÐ°Ð½ÑÐ¾Ð¼ Kyoto Kagaku PET/ SPECT Thorax Phantom PH-63, Ð·Ð°Ð¿Ð¾Ð»Ð½ÐµÐ½Ð½ÑÐ¹ ÑÐ°ÑÑÐ²Ð¾ÑÐ¾Ð¼ 225ÐÑ. ÐÐ¾ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÐ¼ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ°Ð¼ Ð±ÑÐ»Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ ÐºÐ¾ÑÑÑÐ¸ÑÐ¸ÐµÐ½ÑÑ ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸. Ð¡ Ð¿Ð¾Ð¼Ð¾ÑÑÑ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ð³Ð¾ Ð¿Ð°ÐºÐµÑÐ° Vidar Dicom Viewer 3.3 Ð±ÑÐ»Ð¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ñ Ð¿ÑÐ¾ÑÐ¾ÐºÐ¾Ð»Ñ ÑÐºÐ°Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ ÑÐµÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ Ð¸Ð·Ð¾Ð±ÑÐ°Ð¶ÐµÐ½Ð¸Ñ, Ð¿Ð¾ ÐºÐ¾ÑÐ¾ÑÑÐ¼ Ð² Ð´Ð°Ð»ÑÐ½ÐµÐ¹ÑÐµÐ¼ Ð¾ÑÐµÐ½Ð¸Ð²Ð°Ð»Ð¾ÑÑ Ð¸Ñ Ð²Ð»Ð¸ÑÐ½Ð¸Ðµ Ð½Ð° ÐºÐ¾ÑÑÑÐ¸ÑÐ¸ÐµÐ½ÑÑ ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸. Ð Ð¸ÑÐ¾Ð³Ðµ Ð±ÑÐ»Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¾Ð¿ÑÐ¸Ð¼Ð°Ð»ÑÐ½ÑÐµ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ ÑÐµÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ Ð¸Ð·Ð¾Ð±ÑÐ°Ð¶ÐµÐ½Ð¸Ñ, Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ ÑÐ¸ÑÑÐµÐ¼Ñ Ð´ÐµÑÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ ÑÐ±Ð¾ÑÐ° Ð´Ð°Ð½Ð½ÑÑ ÐÐ¤Ð­ÐÐ¢ Ð´Ð»Ñ 225ÐÑ.
description: The given work is devoted to sensitivity estimation for SPECT/CT systems for 225Ac with different detection systems, data receiving options and for different image reconstructions using three SPECT/CT scanners. The work has been done on the base of the Federal State Budgetary Institution âNational medical oncology research center named after N.N. Petrovâ and Federal State Budgetary Institution âAll-Russian center of emergency and radiation medicine named after A.M. Nikiforovâ, where anthropomorphic phantom Kyoto Kagaku PET/SPECT Thorax Phantom PH-63, which had been filled with 225Ac solution, has been scanned using GE Discovery NM 630 scanner; Siemens Symbia T16 scanner with MEGP collimator; Siemens Symbia T16 scanner with HEGP collimator. Sensitivity factors has been obtained with received data. Scanning protocols and image reconstruction options have been obtained using software Vidar Dicom Viewer 3.3, which have been later used to estimate their influence on sensitivity factors. As a result, optimal image reconstruction options, detection system options and data receiving options for 225Ac have been defined.