cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth
Creators: name: Zhou, Can
name: Vaziri, Cyrus
name: Li, Pingping
name: Li, Juan
name: Liu, Peijun
name: Zhang, Jianmin
name: Wang, Bo
name: Ren, Yu
name: Jiang, Yina
name: Wang, Yaochun
name: Liang, Zheyong
name: Yang, Lu
name: Yang, Jin
name: Luo, Zhijun
name: Liu, Jie
name: He, Fang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Loss or dysfunction of tumor suppressor retinoblastoma (RB) is a common feature in various tumors, and contributes to cancer cell stemness and drug resistance to cancer therapy. However, the strategy to suppress or eliminate Rb-deficient tumor cells remains unclear. In the present study, we accidentally found that reduction of DNA replication licensing factor MCM7 induced more apoptosis in RB-deficient tumor cells than in control tumor cells. Moreover, after a drug screening and further studies, we demonstrated that statin drug Simvastatin and Atorvastatin were able to inhibit MCM7 and RB expressions. Further study showed that Simvastatin and Atorvastatin induced more chromosome breaks and gaps of Rb-deficient tumor cells than control tumor cells. In vivo results showed that Simvastatin and Atorvastatin significantly suppressed Rb-deficient tumor growth than control in xenograft mouse models. The present work demonstrates that ‘old' lipid-lowering drugs statins are novel weapons against RB-deficient tumors due to their effects on suppressing MCM7 protein levels.
title: A novel classification system for thoracic gallstones
Creators: name: Lott, Alexander
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Biliary Tract / Gallbladder
subject: Thorax
subject: CT
subject: CT-High Resolution
subject: Cholangiography
subject: Foreign bodies
subject: Calcifications / Calculi

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Migration of spilled gallstones into the thorax following laparoscopic cholecystectomy (LC) is extremely rare, yet can be associated with prolonged suffering and late diagnosis. Little is known about the condition's presentation, treatment...
Neural network connectivity during a distress tolerance task among individuals with substance use disorder
Creators: name: Reese, Elizabeth
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Clinical Psychology
subject: Life Sciences
subject: Neuroscience and Neurobiology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: The overall aim of the current study is to examine functional connectivity (FC) within and between neural networks among treatment-seeking adults with substance use disorder (SUD) at multiple timepoints across three distinct conditions: rest (Phase1) followed by no-stress (Phase2) and stress (Phase3) phases of a distress tolerance (DT) task. Change in neural network FC and its relationship to DT and substance use outcomes will be examined.
Components of entrepreneurial idea Pitch: AQualitative analysis from an Entrepreneurial classroom
Creators: name: Kunte, Manjiri
Publisher: name: Stamford International University, Thailand
Year: 2018
Subjects: Entrepreneurship, Pitch deck, pitching presentations, passion, knowledge, narratives, visual presentation, Thailand

description: ASEAN Journal of Management & Innovation, 5, 2, p 107-117
title: Serial flow-sensitive 4D MRI in paediatric patients with Marfan syndrome for early risk stratification of progressive aortic disease
Creators: name: Geiger, Julia
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Paediatric
subject: Vascular
subject: Cardiovascular system
subject: MR
subject: MR-Angiography
subject: Diagnostic procedure
subject: Haemodynamics / Flow dynamics

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Marfan syndrome (MFS) is a genetic disorder of the connective tissue caused by mutations of the fibrillin 1 and transforming growth factor genes [1,2]. Diagnosis relies on clinical criteria and genetic findings, which are summarized in the revised...
title: Über Wasserstoffbrücken, VII. Die Struktur von 6-Hydrozy-fulven- oder Cyclopentadien-aldehyden
Creators: name: Hafner, Klaus
name: Kramer, Horst E. A.
name: Musso, Hans
name: Ploss, Gottfried
name: Schulz, Günther
Publisher: name: Wiley
Year: 2023

description: IR-und NMR-Spektren zeigen, daß eine Aldehyd- oder Ketogruppe am Cyclopentadien nicht ausreicht, um die tautomere 6- Hydroxy-fulven-Struktur zu stabilisieren. Bietet jedoch eine zweite Aldehydgruppe in der Nachbarstellung die Möglichkeit zu einer sehr festen intramolekularen Wasserstoffbrücke, so wird ausschließlich die 6-Hydroxy-fulven-aldehyd-(1)-Form ausgebildet. Die Struktur von 6-Amino -fulven-aldehyd-Derivaten wird ebenfalls aus den Spektren abgeleitet.
ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome
Creators: name: Miller,
name: Zak,
name: Scott,
name: Aylsworth,
name: Wieczorek,
name: Slee,
name: Zakaria,
name: Schneider,
name: Innes,
name: Choy,
name: Joss,
name: Vernet,
name: Dubbs,
name: Lacassie,
name: Escobar,
name: Lygate,
name: Chen,
name: Prin,
name: Andrieux,
name: Jun,
name: Lu,
name: Parker,
name: Vives,
name: Kotzot,
name: Tucker,
name: Mohun,
name: Dieux-Coeslier,
name: Haberlandt,
name: Collins,
name: Pretorius,
name: Rosenfeld,
name: Zinner,
name: Szumska,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Chromosomal abnormalities are implicated in a substantial number of human developmental syndromes, but for many such disorders little is known about the causative genes. The recently described 1q41q42 microdeletion syndrome is characterized by characteristic dysmorphic features, intellectual disability and brain morphological abnormalities, but the precise genetic basis for these abnormalities remains unknown. Here, our detailed analysis of the genetic abnormalities of 1q41q42 microdeletion cases identified TP53BP2, which encodes apoptosis-stimulating protein of p53 2 (ASPP2), as a candidate gene for brain abnormalities. Consistent with this, Trp53bp2-deficient mice show dilation of lateral ventricles resembling the phenotype of 1q41q42 microdeletion patients. Trp53bp2 deficiency causes 100% neonatal lethality in the C57BL/6 background associated with a high incidence of neural tube defects and a range of developmental abnormalities such as congenital heart defects, coloboma, microphthalmia, urogenital and craniofacial abnormalities. Interestingly, abnormalities show a high degree of overlap with 1q41q42 microdeletion-associated abnormalities. These findings identify TP53BP2 as a strong candidate causative gene for central nervous system (CNS) defects in 1q41q42 microdeletion syndrome, and open new avenues for investigation of the mechanisms underlying CNS abnormalities.
The Model of Service Qualityat Na Yai Arm Sub-District Administrative Organization, Na Yai Arm District, Chantaburi Province, Thailand.
Creators: name: Pongsatean Luengalongkot
Publisher: name: Burapha University
Year: 2018
Subjects: Good Governance, Service Quality, Sub-District Administrative Organization

description: ASEAN Journal of Management & Innovation, 5, 2, p 218-225
Quark Nugget Dark Matter: No contradictions with neutrino flux constraints
Creators: name: Lawson, Kyle
name: Zhitnitsky, Ariel R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It has recently been claimed that dark matter in form of quark nuggets cannot account for more than 20% of the dark matter density. This claim is based on constraints on the neutrino flux in 20-50 MeV range where the sensitivity of underground neutrino detectors such as Super-Kamiokande have their highest signal-to-noise ratio. We argue that this claim depends crucially on the assumption that the annihilation of visible baryons with an antiquark nugget will generate a neutrino spectrum similar to the conventional baryon-antibaryon annihilation spectrum in vacuum. However, this assumption does not hold for the nuggets in a colour superconducting phase where the lightest pseudo Goldstone mesons (the pions and Kaons) have masses in the 20 MeV range, in contrast with conventional pion mass of roughly 140 MeV. Thus, the decay of these light pseudo Goldstone bosons of the CS phase cannot produce highly energetic neutrinos in the 20-50 MeV energy range.
description: expanded analysis of low energy neutrino constraints and separate treatment of antineutrino results
title: Comparison of noncontrast-enhanced renal MRA contrast-enhanced MRA in subjects with renovascular hypertension diagnosis
Creators: name: Aydın, Elçin
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Arteries / Aorta
subject: Kidney
subject: Vascular
subject: MR-Angiography
subject: MR
subject: Screening
subject: Hypertension

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Renovascular hypertension (RVH) is a potentially curable cause of hypertension. Non-invasive visualization of renal arteries for early diagnosis and urgent endovascular management is effective in most of the patients. However Doppler ultrasound is...
New Minimal SO(10) GUT : A Theory for All Epochs
Creators: name: Aulakh, Charanjit S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Supersymmetric SO(10) theory ("NMSO(10)GUT") based on the\hfil\break ${\bf{210+126 +\oot}}$ Higgs system proposed in 1982 has evolved into a realistic theory capable of fitting the known low energy Particle Physics data besides providing a Dark matter candidate and embedding Inflationary Cosmology. It dynamically resolves longstanding issues such as fast dimension five operator mediated proton decay in Susy GUTs by allowing explicit and complete calculation of crucial threshold effects at $M_{Susy}$ and $M_{GUT}$ in terms of fundamental parameters. This shows that SO(10) Yukawas responsible for observed fermion masses as well as operator dimension 5 mediated proton decay can be highly suppressed on a "Higgs dissolution edge" in the parameter space of GUTs with rich superheavy spectra. This novel and generically relevant result highlights the need for every realistic UV completion model with a large/infinite number of heavy fields coupled to the light Higgs doublets to explicitly account for the large wave function renormalization effects on emergent light Higgs fields in order to be considered a quantitatively well defined candidate UV completion. The NMSGUT predicts large soft Susy breaking trilinear couplings and distinctive sparticle spectra. Measurable or near measurable level of tensor perturbations- and thus large Inflaton mass scale- may be accommodated by Supersymetric Seesaw inflation within the NMSGUT based on an LHN flat direction Inflaton if the Higgs component contains contributions from heavy Higgs components. Successful NMSGUT fits suggest a \emph{renormalizable} Yukawon Ultra minimal gauged theory of flavor based upon the NMSGUT Higgs structure.
description: 20 Pages, 1 Fig., PdfLatex. Proceedings of UNICOS2014. References and historical comments added
When Engaging in Hedonic and Long-Term Goals Pays Off: The Role of Momentary Affect in Explaining the Relationship Between Long-Term Goals, Hedonic Goals, and Well-Being
Creators: name: van Halem, Sjoerd
name: van Roekel, Eeske
name: Trompetter, Hester
name: Denissen, Jaap
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: In this study, we test the specific affective conditions under which long-term and hedonic goal pursuits are related to overall well-being
Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts
Creators: name: Dou, Yali
name: Wang, Zhong
name: Liu, Liu
name: Wang, Li
name: Gnatovskiy, Leonid
name: Lei, Ienglam
name: Li, Yangbing
name: Qian, Li
name: Karatas, Hacer
name: Wang, Shaomeng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Generation of induced cardiomyocytes (iCMs) directly from fibroblasts offers a great opportunity for cardiac disease modeling and cardiac regeneration. A major challenge of iCM generation is the low conversion rate. To address this issue, we attempted to identify small molecules that could potentiate the reprogramming ability towards cardiac fate by removing inhibitory roadblocks. Using mouse embryonic fibroblasts as the starting cell source, we first screened 47 cardiac development related epigenetic and transcription factors, and identified an unexpected role of H3K4 methyltransferase Mll1 and related factor Men1 in inhibiting iCM reprogramming. We then applied small molecules (MM408 and MI503) of Mll1 pathway inhibitors and observed an improved efficiency in converting embryonic fibroblasts and cardiac fibroblasts into functional cardiomyocyte-like cells. We further observed that these inhibitors directly suppressed the expression of Mll1 target gene Ebf1 involved in adipocyte differentiation. Consequently, Mll1 inhibition significantly decreased the formation of adipocytes during iCM induction. Therefore, Mll1 inhibitors likely increased iCM efficiency by suppressing alternative lineage gene expression. Our studies show that targeting Mll1 dependent H3K4 methyltransferase activity provides specificity in the process of cardiac reprogramming. These findings shed new light on the molecular mechanisms underlying cardiac conversion of fibroblasts and provide novel targets and small molecules to improve iCM reprogramming for clinical applications.
Open Materials - Destabilization in Self-Ratings of the Psychotherapeutic Process is associated with Better Treatment Outcome in Patients with Mood Disorders
Creators: name: Olthof, Merlijn
name: Hasselman, Fred
Publisher: name: Open Science Framework
Year: 2022

description: Open Materials for the study Destabilization in Self-Ratings of the Psychotherapeutic Process is Associated with Better Treatment Outcome.
title: Benefits of weight bearing MRI in the functional exam of meniscus instability
Creators: name: Giannini, Silvana
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal joint
subject: MR
subject: Experimental investigations
subject: Education and training

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Normal 0 14 false false false EN-US JA X-NONE The aim of this trial is to demonstrate meniscus instability in patients suffering from chronic gonalgia as well as medial and lateral meniscus through a weight bearing functional...
IMPACT OF PHYSICAL CHEMICAL AND STRUCTURES CHARACTERISTICS OF BIOMATERIALS ON BONE FORMATION AFTER MAXILLARY SINUS LIFTING: systematic literature review
Creators: name: Cornacchia, Gianfilippo
name: Zenóbio, Élton
name: de Araújo, Vânia
name: Mendes, Polianne
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Dental Materials
subject: Medicine and Health Sciences
subject: Dentistry
subject: FOS: Clinical medicine
subject: Bone graft. Biocompatible materials. Biomaterials. Maxillary sinus. Physicochemical propretis.

description: Research project for a systematic review of the literature that seeks to assess the physical-chemical and structural impacts of xenogenous and alloplastic biomaterials in the lifting of the maxillary sinuses.
Chiral Gravitomagnetic Effect in Topological Superconductors and Superfluids
Creators: name: Sekine, Akihiko
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We theoretically search for dynamical cross-correlated responses of three-dimensional topological superconductors and superfluids. It has been suggested that a gravitational topological term, which is analogous to the theta term in topological insulators, can be derived in three-dimensional time-reversal invariant topological superconductors and superfluids, and that the dynamical gravitational axion field can be realized by the fluctuation of the relative phase, i.e., by the Leggett mode between topological $p$-wave pairing and conventional $s$-wave pairing. In the presence of the dynamical gravitational axion field, we propose the emergence of the "chiral gravitomagnetic effect", a thermal current generation by gravitomagnetic fields, i.e., by mechanical rotations. This effect can be regarded as a thermal counterpart of the chiral magnetic effect which has been studied mainly in Weyl semimetals. We also show the occurrence of the anomalous thermal Hall effect in the bulk. We discuss a possible application of our study to the thermal responses of Weyl superconductors.
description: 6 pages, 1 figure, 1 table
UHRF1 is required for basal stem cell proliferation in response to airway injury
Creators: name: Sun, Tao
name: Liu, Si-Qi
name: Wu, Haiyang
name: Li, Qi-Jing
name: Wang, Xiao-Fan
name: Xiang, Handan
name: Alexander, Peter B.
name: Lopez, Omar
name: Wan, Ying
name: Yuan, Lifeng
name: Lau, Calvin
name: Gao, Xia
name: Ding, Yi
name: Chong, Mengyang
name: Chen, Rui
name: Randell, Scott H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Cellular senescence is a cell fate characterized by an irreversible cell cycle arrest, but the molecular mechanism underlying this senescence hallmark remains poorly understood. Through an unbiased search for novel senescence regulators in airway basal cells, we discovered that the epigenetic regulator ubiquitin-like with PHD and ring finger domain-containing protein 1 (UHRF1) is critical for regulating cell cycle progression. Upon injury, basal cells in the mouse airway rapidly induce the expression of UHRF1 in order to stimulate stem cell proliferation and tissue repair. Targeted depletion of Uhrf1 specifically in airway basal cells causes a profound defect in cell cycle progression. Consistently, cultured primary human basal cells lacking UHRF1 do not exhibit cell death or differentiation phenotypes but undergo a spontaneous program of senescence. Mechanistically, UHRF1 loss induces G1 cell cycle arrest by abrogating DNA replication factory formation as evidenced by loss of proliferating cell nuclear antigen (PCNA) puncta and an inability to enter the first cell cycle. This proliferation defect is partially mediated by the p15 pathway. Overall, our study provides the first evidence of an indispensable role of UHRF1 in somatic stem cells proliferation during the process of airway regeneration.
Validity of a Sexual Misconduct Educational Training Programs
Creators: name: Lee, Ryan
name: Frankowski, Scott
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: College Sexual Assault Training
subject: Sexual Assault training
subject: Validity of Sexual Assault trainings

description: This research will looks to determine if sexual misconduct educational training programs are valid in their ability to educate, change attitudes toward sexual misconduct, and if attitude changes stay changed over a period of time.
Factors associated with outdoor winter walking for older adults: A scoping review protocol
Creators: name: Bergen, Kyle
name: Jubenvill, Megan
name: Shaw, Kyle
name: Steen, Erin
name: Loewen, Hal
name: Mbabaali, Sophia
name: Barclay, Ruth
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Physiotherapy
subject: Medicine and Health Sciences
subject: Rehabilitation and Therapy
subject: Physical Therapy

description: This scoping review aims to identify internal and external factors associated with winter walking in older adults.
title: Diffusion imaging of rectal cancer: comparison between four different models
Creators: name: Papanikolaou, Nickolas
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Colon
subject: Gastrointestinal tract
subject: MR-Diffusion/Perfusion
subject: Technical aspects
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of the current poster was to compare four diffusion models including mono-exponential and bi-exponential both Gaussian and non-Gaussian in patients with rectal adenocarcinoma. Gaussian mono-exponential model associated to the Apparent...
A Mouse Model of Zika Virus Pathogenesis
Creators: name: Lazear, Helen M.
name: Smith, Amber M.
name: Fernandez, Estefania
name: Platt, Derek J.
name: Govero, Jennifer
name: Miner, Jonathan J.
name: Diamond, Michael S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: SummaryThe ongoing Zika virus (ZIKV) epidemic and unexpected clinical outcomes, including Guillain-Barré syndrome and birth defects, has brought an urgent need for animal models. We evaluated infection and pathogenesis with contemporary and historical ZIKV strains in immunocompetent mice and mice lacking components of the antiviral response. Four- to six-week-old Irf3−/− Irf5−/− Irf7−/− triple knockout mice, which produce little interferon α/β, and mice lacking the interferon receptor (Ifnar1−/−) developed neurological disease and succumbed to ZIKV infection, whereas single Irf3−/−, Irf5−/−, and Mavs−/− knockout mice exhibited no overt illness. Ifnar1−/− mice sustained high viral loads in the brain and spinal cord, consistent with evidence that ZIKV causes neurodevelopmental defects in human fetuses. The testes of Ifnar1−/− mice had the highest viral loads, which is relevant to sexual transmission of ZIKV. This model of ZIKV pathogenesis will be valuable for evaluating vaccines and therapeutics as well as understanding disease pathogenesis.
title: Haemorrhagic transformation in different ischemic stroke pathogenetic subtypes: MRI investigation
Creators: name: Suslin, Alexander
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: MR
subject: Diagnostic procedure
subject: Haemorrhage
subject: Ischaemia / Infarction

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of our study was to was to evaluate haemorragic transformayion (HT) in different ischemic stroke pathogenetic subtypes and influence of HT on neurological...
Collective neutrino oscillations and spontaneous symmetry breaking
Creators: name: Duan, Huaiyu
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Neutrino oscillations in a hot and dense astrophysical environment such as a core-collapse supernova pose a challenging, seven-dimensional flavor transport problem. To make the problem even more difficult (and interesting), neutrinos can experience collective oscillations through nonlinear refraction in the dense neutrino medium in this environment. Significant progress has been made in the last decade towards the understanding of collective neutrino oscillations in various simplified neutrino gas models with imposed symmetries and reduced dimensions. However, a series of recent studies seem to have "reset" this progress by showing that these models may not be compatible with collective neutrino oscillations because the latter can break the symmetries spontaneously if they are not imposed. We review some of the key concepts of collective neutrino oscillations by using a few simple toy models. We also elucidate the breaking of spatial and directional symmetries in these models because of collective oscillations.
description: 18 pages, 4 figures
title: Dental radiology in childhood: dosimetry and optimisation of dental radiographic digital studies
Creators: name: Testa, Francesco
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Head and neck
subject: Radioprotection / Radiation dose
subject: Conventional radiography
subject: Diagnostic procedure
subject: Quality assurance

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Most frequently dental and orthodontic cares in childhood need X-Ray imaging such as panoramic and cephalometric radiograms. These procedures may administer a significant radiation dose on young people. Aim of this work is to evaluate and to...
title: Can we predict fracture in pathologic altered bone of the proximal femur using only plain radiographs?
Creators: name: Simunovic, Marko
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal bone
subject: Conventional radiography
subject: Outcomes analysis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Simple bone cyst (SBC) is the most common benign lytic bone lesion in childhood, mainly affecting the proximal femur and proximal humerus. SBC located in a biomechanically unfavourable area such as the proximal femur significantly raises risk of...
Optimal designs for the proportional interference model
Creators: name: Li, Kang
name: Zheng, Wei
name: Ai, Mingyao
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: The interference model has been widely used and studied in block experiments where the treatment for a particular plot has effects on its neighbor plots. In this paper, we study optimal circular designs for the proportional interference model, in which the neighbor effects of a treatment are proportional to its direct effect. Kiefer's equivalence theorems for estimating both the direct and total treatment effects are developed with respect to the criteria of A, D, E and T. Parallel studies are carried out for the undirectional model, where the neighbor effects do not depend on whether they are from the left or right. Moreover, the connection between optimal designs for the directional and undiretional models is built. Importantly, one can easily develop a computer program for finding optimal designs based on these theorems.
description: Published at http://dx.doi.org/10.1214/15-AOS1317 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Replication of Berman (2020) Moral Choice When Harming is Unavoidable -BYU-Idaho Winter 2021
Creators: name: Wolff, Abygail
name: Lange, Mary
name: Norconk, Spencer
name: Wiggins, Bradford
name: Riddle, Loren
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: The members of the research team are Abygail Wolff, Mary Lange, Spencer Norconk, and Loren Riddle, under supervision of Brady Wiggins, at BYU-Idaho. The original study, Moral Choice When Harming is Unavoidable, was done by Jonathan Z. Berman and Daniella Kupor in 2020: The specific study that is being replicated is study 1, "Pulling Life support from the terminally ill." This particular study was exploring the idea that most people avoid inflicting harm when there is an option to do no harm, and that individuals may be more willing to do greater harm for a greater benefit when harming is an unavoidable choice. They used the chi square test for their experiment. They found that the results of the study confirmed their hypothesis, and that participants were more likely to do greater harm where greater benefit was also a factor in unavoidable harm situations. We are conducting a replication of this study at Brigham Young University - Idaho, with our participants being students from the General Psychology Class. In our replication of the study we have added in one more hypothesis, We want to see if Gender may affect the individuals moral reasoning, this hypothesis won't affect the method as we are already gathering information on the participants gender. An individuals gender may have an impact on their personality and we want to see if that impact may affect their moral reasoning.
ความเปราะบางทางสังคมและการประเมินความเสี่ยงต่อภัยพิบัติของพื้นที่เมือง กรณีศึกษาเทศบาลนครอุดรธานี
Creators: name: สุธี อนันต์สุขสมศรี
Publisher: name: Thammasat Printing House
Year: 2018
Subjects: ความเสี่ยงต่อภัยพิบัติ
ความเปราะบางทางสังคม
เมืองอุดรธานี

description: Journal of Architectural/Planning Research and Studies, 15, 1, 69-86
แนวทางการพัฒนาความปลอดภัยทางถนนของชุมชนมหาวิทยาลัยและพื้นที่โดยรอบอย่างยั่งยืน กรณีศึกษา มหาวิทยาลัยธรรมศาสตร์ ศูนย์รังสิต
Creators: name: ภาวิณี เอี่ยมตระกูล
Publisher: name: Thammasat Printing House
Year: 2018
Subjects: ชุมชนมหาวิทยาลัย
ความปลอดภัยทางถนน
การพัฒนาอย่างยั่งยืน

description: Journal of Architectural/Planning Research and Studies, 15, 1, 49-68
Repeated Narration of the Transition to College
Creators: name: McLean, Kate
name: Lilgendahl, Jennifer
name: Le, Benjamin
name: Dunlap, David
name: Patterson, Aubrie
name: Peterson, Abigayle
name: Payne, Nathanael
name: Tiemersma, Kody
name: Turner, Kit
name: wolin, Hannah
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: See attached doc for pre-registration of qualitative analyses.
title: Diffusion weighted MR imaging of breast - can it add to the specificity of breast MRI? Report from a tertiary cancer care hospital in South India
Creators: name: Koshy, SUMOD
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: Oncology
subject: MR
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Imaging sequences
subject: Cancer
subject: Multidisciplinary cancer care
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Primary objective: To evaluate the role of diffusion weighted imaging (DWI) in improving the diagnostic accuracy of dynamic contrast enhanced MRI breast. Secondary objective: To calculate a cut off ADC value to differentiate benign and malignant...
Discovering the Right Things to Design with Artificial Intelligence
Creators: name: Yildirim, Nur
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: Advances in artificial intelligence (AI) enable impressive new technical capabilities: computers can diagnose diseases, translate between languages, and drive cars. Interestingly, today nearly 90% of AI initiatives fail; few projects survive until deployment. I argue that a lack of effective ideation leads teams to select suboptimal innovations to pursue. In addition, AI product teams fail to see low-hanging fruit, situations where simple predictive models can generate value for users and stakeholders. Currently, data science teams propose innovations customers do not want, while product teams ask for things AI cannot do. As AI capabilities become more pervasive and commoditized, discovering the right human problems to solve while mitigating potential harm remains a great challenge.
My research addresses this breakdown in early stage ideation and problem formulation. I studied practitioners and observed that teams better at ideating are more effective in developing AI solutions that generate value and minimize risk. Based on the industry best practices, I created new innovation processes and resources for helping cross-functional product teams effectively explore the AI solution space before selecting what to implement. I developed a taxonomy of AI capabilities and examples of these in product forms. These resources sensitize stakeholders to what AI can do and search for opportunities where these might be valuable. I developed a hybrid ideation method that blends technology-centered development and human-centered design. I conducted a preliminary assessmentof these resources and processes through case studies with innovation teams working in critical care,radiology, insurance, and accounting. Overall, this dissertation provides a glimpse into the future of human-centered AI innovation, where human needs and concerns are given equal importance as technical advances in deciding what to build with artificial intelligence.
title: Magnetic resonance imaging of the sacroiliac joints in SpA: with or without intravenous contrast media?
Creators: name: Gentili, Francesco
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal bone
subject: Musculoskeletal joint
subject: Musculoskeletal system
subject: MR
subject: Conventional radiography
subject: Decision analysis
subject: Treatment effects
subject: Diagnostic procedure
subject: Arthritides
subject: Inflammation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Spondyloarthropathies (SpA) are a group of inflammatory arthritis which consist of ankylosing spondylitis, psoriatic arthritis, arthritis/spondylitis associated with inflammatory bowel disease and reactive arthritis [1]. Lower inflammatory back pain...
พฤติกรรมเชิงพื้นที่ในสถานที่ทำงานสร้างสรรค์: การเชื่อมโยงระหว่างพฤติกรรมสร้างสรรค์และการสร้างนวัตกรรมกับลักษณะกายภาพในสำนักงาน
Creators: name: ทิพย์สุดา  จันทร์แจ่มหล้า
Publisher: name: Thammasat Printing House
Year: 2018
Subjects: สำนักงานสร้างสรรค์
พื้นที่ทำงาน
การร่วมมือกันทำงาน
พฤติกรรมการทำงาน
ความสร้างสรรค์
พฤติกรรมการใช้พื้นที่

description: Journal of Architectural/Planning Research and Studies, 15, 1, 97-112
Knowledge Representation of Requirements Documents Using Natural Language Processing
Creators: name: Schlutter, Aaron
name: Vogelsang, Andreas
Publisher: name: Technische Universität Berlin
Year: 2018
Subjects: subject: 004 Datenverarbeitung; Informatik
subject: natural language processing
subject: knowledge representation
subject: automotive software
subject: requirements
subject: industrial systems
subject: Stanford CoreNLP
subject: Semantic Role Labeling
subject: NLP

description: Complex systems such as automotive software systems are usually broken down into subsystems that are specified and developed in isolation and afterwards integrated to provide the functionality of the desired system. This results in a large number of requirements documents for each subsystem written by different people and in different departments. Requirements engineers are challenged by comprehending the concepts mentioned in a requirement because coherent information is spread over several requirements documents. In this paper, we describe a natural language processing pipeline that we developed to transform a set of heterogeneous natural language requirements into a knowledge representation graph. The graph provides an orthogonal view onto the concepts and relations written in the requirements. We provide a first validation of the approach by applying it to two requirements documents including more than 7,000 requirements from industrial systems. We conclude the paper by stating open challenges and potential application of the knowledge representation graph.
title: Which modifications to abstracts presented orally at radiology conferences are associated with high impact factor journal publication?
Creators: name: Wareham, James
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Computer applications
subject: PACS
subject: Statistics
subject: Comparative studies
subject: Education
subject: Education and training

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Studies presented orally at medical conferences are often adapted prior to journal publication, for example bringing additional authors into the study. There is a paucity of studies analyzing which modifications to studies presented at medical...
การทดสอบการถ่ายเทความร้อนของแผ่นวัสดุที่ทำจากวัสดุเหลือใช้ทางการเกษตรโดยมีปูนซีเมนต์เป็นตัวประสาน
Creators: name: พันธ์ศักดิ์ ภักดี
Publisher: name: Thammasat Printing House
Year: 2018
Subjects: วัสดุเหลือใช้ทางการเกษตร
การถ่ายเทความร้อน
สัมประสิทธิ์การนำความร้อน

description: Journal of Architectural/Planning Research and Studies, 15, 1, 135-146
title: Spectrum of percutaneous transhepatic endovascular PV interventions - indications, technique, complications
Creators: name: Mizandari, Malkhaz
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Interventional vascular
subject: Ultrasound
subject: CT
subject: Fluoroscopy
subject: Ablation procedures
subject: Dilation
subject: Stents

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: PV angioplasty by balloon dilatation and stenting is accepted low-invasive technique for recanalization of portal vein strictures, caused by pancreatic and biliary neoplasms (1, 2,7,10), benign stenosis (5,6), postsurgery complications (9). Few...
NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses
Creators: name: Liu, Yong
name: Petrucelli, Alex
name: Tsao, Li-Chung
name: Mo, Jinyao
name: Sempowski, Gregory D.
name: Feng, Hui
name: Guo, Haitao
name: Ting, Jenny P.-Y.
name: Wang, Qi
name: Zhang, Lu
name: Barefoot, Brice
name: Duncan, Joseph A.
name: Zhang, Yanping
name: Zhang, Aiping
name: König, Renate
name: Colberg-Poley, Anamaris M.
name: Chanda, Sumit K.
name: Deng, Meng
name: Wen, Haitao
name: Su, Lishan
name: Riess, Maximilian
name: Yoh, Sunnie M.
name: Zhang, Zhigang
name: Lemon, Stanley M.
name: Samo, Melissa
name: Damania, Blossom
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: SummaryUnderstanding the negative regulators of antiviral immune responses will be critical for advancing immune-modulated antiviral strategies. NLRX1, an NLR protein that negatively regulates innate immunity, was previously identified in an unbiased siRNA screen as required for HIV infection. We find that NLRX1 depletion results in impaired nuclear import of HIV-1 DNA in human monocytic cells. Additionally, NLRX1 was observed to reduce type-I interferon (IFN-I) and cytokines in response to HIV-1 reverse-transcribed DNA. NLRX1 sequesters the DNA-sensing adaptor STING from interaction with TANK-binding kinase 1 (TBK1), which is a requisite for IFN-1 induction in response to DNA. NLRX1-deficient cells generate an amplified STING-dependent host response to cytosolic DNA, c-di-GMP, cGAMP, HIV-1, and DNA viruses. Accordingly, Nlrx1−/− mice infected with DNA viruses exhibit enhanced innate immunity and reduced viral load. Thus, NLRX1 is a negative regulator of the host innate immune response to HIV-1 and DNA viruses.
Outcomes from healthy eating and physical activity recognition programs in early childcare and education: A scoping review
Creators: name: Arlinghaus, Katherine
name: Hunt, Shanda
name: Stang, Jamie
name: Pass, Molly
name: Wagner, Gerit
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences

description: This scoping review seeks to answer the following question: What is the extent and nature of available evidence on outcomes from recognition programs for healthy eating and physical activity in early childcare and education settings? To accomplish this, a systematic search of literature evaluating early childhood and education nutrition-related recognition programs will be conducted. We will use this search to map out the characteristics and range of methodologies and criteria used to evaluate recognition programs, identify gaps in evaluation outcomes, and synthesize existing evidence for the use of recognition programs. The intent of this project is to provide informed recommendations for public health professionals interested in using recognition systems to improve nutrition and physical activity practices used in early childcare and education settings.
Ubaldino Peruzzi a Luigi Calamai (1 aprile 1848)
Creators: name: Peruzzi, Ubaldino
name: Calamai, Luigi
Publisher: name: Zenodo
Year: 2023
Subjects: Accademia dei Georgofili
Peruzzi, Ubaldino
Calamai, Luigi
Lettera
Letter
Carteggio
Correspondence
1848

description: Lettera di Ubaldino Peruzzi a Luigi Calamai del 1 aprile 1848. Segnatura dell'unità documentale: Archivio storico dell’Accademia dei Georgofili, Carteggio, Busta 29, 2190. Natura: Manoscritto. Consistenza: cc. 2.
description: Digitalizzato come parte della Mostra virtuale: Ubaldino Peruzzi : un percorso in rete : in occasione del bicentenario della nascita. https://www.georgofili.it/contenuti/ubaldino-peruzzi-un-percorso-in-rete/17485
Sustainable Attitudes and Behaviors
Creators: name: Hopwood, Christopher
name: Bleidorn, Wiebke
name: Lenhausen, Madeline
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Personality and Social Contexts
subject: Health Psychology
subject: Environmental Studies
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: This study was designed to explore the structure and correlates of sustainable attitudes and behaviors
Formulas for Partition $k$-Tuples with $t$-Cores
Creators: name: Chern, Shane
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 11P84 (Primary), 11F11, 11M36, 05A17 (Secondary)

description: Let $A_{t,k}(n)$ denote the number of partition $k$-tuples of $n$ where each partition is $t$-core. In this paper, we establish formulas of $A_{t,k}(n)$ for some values of $t$ and $k$ by employing the method of modular forms, which extends Wang's result for $t=3$ and $k=2,3$.
description: Final version
Supplementary document for Global search algorithms in automated design of starting points for deep-UV lithography objective - 7132190.pdf
Creators: name: Zoric, Nenad
name: Nie, Yunfeng
name: Thibault, Simon
name: Thomas, Lijo
name: Prodanovic, Radomir
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Supplement 1
A New Way of Representing and Storing Information
Creators: name: Basu, Nirmalya
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Physical Sciences and Mathematics
subject: Applied Mathematics
subject: FOS: Mathematics
subject: Computer Engineering
subject: Computational Engineering
subject: Mathematics
subject: Computer Sciences
subject: Electrical and Computer Engineering
subject: Engineering

description: I have proposed here a new scheme of representing information which is that any physical quantity with a specific identity can be considered to uniquely represent a distinct piece of information (a piece of information different from the one that the physical quantity itself conveys which is that of its identity). Doing so is expected to bring advantage to computing.
Supplementary document for Three-Dimensional Modelling of Near-field Beam Profiles from Grating Couplers using Deep Neural Network - 7161729.pdf
Creators: name: Lim, Yu Dian
name: Tan, Chuan Seng
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Explanatory note for the full Python code
title: The reliability and validity of detecting low dose radiation when using radiation detection applications and devices for smartphones
Creators: name: Erenstein, Hendrik
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Radioprotection / Radiation dose
subject: Radiation physics
subject: Computer applications
subject: Nuclear medicine conventional
subject: Catheter arteriography
subject: Fluoroscopy
subject: Radiation safety
subject: Experimental investigations
subject: Dosimetry

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: According to the World Health Organisation, 1 worldwide, there are 3.6 billion X-ray examinations preformed, 37 million nuclear medicine procedures carried out and 7.5 million radiotherapy treatments given annually. Several of these scenarios...
Origami building blocks: generic and special 4-vertices
Creators: name: Waitukaitis, Scott
name: van Hecke, Martin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Four rigid panels connected by hinges that meet at a point form a 4-vertex, the fundamental building block of origami metamaterials. Here we show how the geometry of 4-vertices, given by the sector angles of each plate, affects their folding behavior. For generic vertices, we distinguish three vertex types and two subtypes. We establish relationships based on the relative sizes of the sector angles to determine which folds can fully close and the possible mountain-valley assignments. Next, we consider what occurs when sector angles or sums thereof are set equal, which results in 16 special vertex types. One of these, flat-foldable vertices, has been studied extensively, but we show that a wide variety of qualitatively different folding motions exist for the other 15 special and 3 generic types. Our work establishes a straightforward set of rules for understanding the folding motion of both generic and special 4-vertices and serves as a roadmap for designing origami metamaterials.
description: 8 pages, 9 figures
title: Fetal body MRI: is it feasible and diagnostic in a 1.0-Tesla open magnet? Practicalities and image quality evaluation
Creators: name: Tagalakis, Panagiotis
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Foetal imaging
subject: MR
subject: Imaging sequences
subject: Technical aspects

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To present our experience in imaging the fetal body on a 1.0-Tesla open-MRI scanner, to highlight the practicalities, which may affect the quality of images and correlate diagnostic results with neonatal or post-mortem final...
วัดไทยในแดนใต้: รูปแบบสถาปัตยกรรมกุฏิสงฆ์ในเขต อ.ตากใบ จ.นราธิวาสกับข้อสังเกตเรื่องการก่อรูปและการใช้งานในบริบทสังคมวัฒนธรรมท้องถิ่น
Creators: name: กุลพัชร์ เสนีวงศ์ ณ อยุธยา
Publisher: name: Thammasat Printing House
Year: 2018
Subjects: พุทธศาสนสถาปัตยกรรม
กุฏิสงฆ์
พัฒนาการทางรูปแบบสถาปัตยกรรม
อำเภอตากใบ
จังหวัดนราธิวาส

description: Journal of Architectural/Planning Research and Studies, 15, 1, 147-166
title: Percutaneous management of biliary strictures after liver transplantation: is there a definitive solution?
Creators: name: Dumitru, Radu
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Interventional non-vascular
subject: Biliary Tract / Gallbladder
subject: Fluoroscopy
subject: Ultrasound
subject: MR
subject: Cholangiography
subject: Drainage
subject: Transplantation
subject: Infection

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Still considered the Achiles heel in hepatic transplantation, biliary complications canremain a major source of morbidity. Biliary strictures (which can be either anastomotic or non anastomotic) can be treated percutaneously or via endoscopy (in...