cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
Creators: name: Guen, Yann
name: Rujescu, Dan
name: Zetterberg, Henrik
name: Blennow, Kaj
name: [Und Viele Weitere]
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. Protective HLA-DRB1*04 subtypes strongly bound the aggregation-prone tau PHF6 sequence, however only when acetylated at a lysine (K311), a common posttranslational modification central to tau aggregation. An HLA-DRB1*04-mediated adaptive immune response decreases PD and AD risks, potentially by acting against tau, offering the possibility of therapeutic avenues.
Profound changes in functional structure and dynamics of Serum Albumin in children with nephrotic syndrome : an exploratory research study
Creators: name: Haeri, Haleh H.
name: Eisermann, Jana
name: Schimm, Heike
name: Büscher, Anja K.
name: Hoyer, Peter F.
name: Hinderberger, Dariush
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 540

description: Patients with nephrotic syndrome (NS) suffer from urinary loss of albumin. As a cause, previous studies focused on the glomerular filter rather than analyzing the molecular properties of albumin itself. Later one was initiated by clinical observations indicating unexplained molecular alterations of human serum albumin (HSA) in an NS pediatric patient. Therefore, we examined serum from eight pediatric patients with steroid-sensitive and -resistant NS and compared it with serum from healthy subjects as well as commercial HSA. We used dynamic and electrophoretic light scattering to characterize the protein size and effective surface charge and electron paramagnetic resonance spectroscopy to measure the local environment and binding dynamics of up to seven fatty acids associated with HSA. Our findings suggest that pronounced differences in binding behavior and surface charge of HSA could enhance their filtration through the GBM, leading to direct toxicity of HSA to podocytes.
The puzzling early detection of low velocity 56Ni decay lines in SN 2014J: Hints of a compact remnant
Creators: name: Ouyed, Rachid
name: Leahy, Denis
name: Koning, Nico
name: Staff, Jan E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We show that the low-velocity 56Ni decay lines detected earlier than expected in the type Ia SN 2014J find an explanation in the Quark-Nova Ia model which involves the thermonuclear explosion of a tidally disrupted sub-Chandrasekhar White Dwarf in a tight Neutron-Star-White-Dwarf binary system. The explosion is triggered by impact from the Quark-Nova ejecta on the WD material; the Quark-Nova is the explosive transition of the Neutron star to a Quark star triggered by accretion from a CO torus (the circularized WD material). The presence of a compact remnant (the Quark Star) provides: (i) an additional energy source (spin-down power) which allows us to fit the observed light-curve including the steep early rise; (ii) a central gravitational potential which slows down some of the 56Ni produced to velocities of a few 1000 km/s. In our model, the 56Ni decay lines become optically visible at ~20 days from explosion time in agreement with observations. We list predictions that can provide important tests for our model.
description: 6 pages, 3 figures and 1 Table. Accepted for publication in ApJ. Details on how we compute the Quark-Nova Ia (QNIa) light-curve are provided (see new Appendix). Relevant codes and usage instructions available via a URL link provided in the Appendix. Comments welcome
Thin torus perturbative analysis of elementary excitations in the Gaffnian and Haldane-Rezayi quantum Hall states
Creators: name: Weerasinghe, Amila
name: Seidel, Alexander
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a systematic perturbative approach to study excitations in the thin cylinder/torus limit of the quantum Hall states. The approach is applied to the Haldane-Rezayi and Gaffnian quantum Hall states, which are both expected to have gapless excitations in the usual two-dimensional thermodynamic limit. For the Haldane-Rezayi state, we confirm that gapless excitations are present also in the "one-dimensional" thermodynamic limit of an infinite thin cylinder, in agreement with earlier considerations based on the wave functions alone. In contrast, we identify the lowest excitations of the Gaffnian state in the thin cylinder limit, and conclude that they are gapped, using a combination of perturbative and numerical means. We discuss possible scenarios for the cross-over between the two-dimensional and the one-dimensional thermodynamic limit in this case.
description: 8 pages, 5 figures, published version, improved arguments pertaining higher order perturbation theory
Coating the surface of interconnected Cu2O nanowire arrays with HKUST-1 nanocrystals via electrochemical oxidation
Creators: name: Caddeo, Francesco
name: Himmelstein, Florian
name: Mahmoudi, Behzad
name: Araújo-Cordero, Ana Maria
name: Eberhart, Denis
name: Zhang, Haojie
name: Lindenberg, Titus
name: Hähnel, Angelika
name: Hagendorf, Christian
name: Maijenburg, A. Wouter
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 540

description: Controlling the crystallization of Metal–Organic Frameworks (MOFs) at the nanoscale is currently challenging, and this hinders their utilization for multiple applications including photo(electro)chemistry and sensors. In this work, we show a synthetic protocol that enables the preparation of highly homogeneous Cu2O@MOF nanowires standing on a conductive support with extensive control over the crystallization of the MOF nanoparticles at the surface of the Cu2O nanowires. Cu2O nanowires were first prepared via templated electrodeposition, and then partially converted into the well-known Cu-MOF HKUST-1 by pulsed electrochemical oxidation. We show that the use of PVP as a capping agent during the electrochemical oxidation of Cu2O into HKUST-1 provides control over the growth of the MOF nanocrystals on the surface of the Cu2O nanowires, and that the size of the MOF crystals obtained can be tuned by changing the concentration of PVP dissolved in the electrolyte. In addition, we propose the use of benzoic acid as an alternative to achieve control over the size of the obtained MOF nanocrystals when the use of a capping agent should be avoided.
Representation and Wage Gaps in the Planning Profession
Creators: name: Shin, Eun Jin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Although gender and racial/ethnic equity have been primary concerns in planning, little research has examined whether the planning profession has achieved such equity in its workforce. In this study, I investigated representation and wage gaps by gender and race/ethnicity in the U.S. planning profession. Using Public Use Microdata Sample (PUMS) data, I explored a) whether gender and racial/ethnic gaps exist in representation and wages among planners and b) the extent to which such gaps changed over the 2000–2018 period and how they varied by employment sector. The results showed a substantial increase in the proportion of female planners over the study period. Black and Hispanic planners remained severely underrepresented, especially in the private sector, although the temporal patterns of their representation differed. Despite a significant reduction in the unadjusted gender wage gap among planners over time, the adjusted gap remained constant. Notably, the gender wage gap was significant only among planners with children, likely driven by fatherhood wage premiums. Unlike other related professions, planning did not exhibit significant racial/ethnic wage gaps at the beginning of the study period. However, Black and Hispanic planners in the public sector experienced significant wage penalties later in the study period. Planning employers need to develop strategies to close the gender wage gap, which includes work–life benefits and workplace awareness campaigns to transform the masculine culture in the planning workplace. Results also highlight the need to improve Black and Hispanic planners’ representation, especially in the private sector. Particular focus should be directed toward supporting Black planners, given their decreasing representation in both sectors and their wage penalties in the public sector in recent years. My study further suggests that interventions that hold public sector employers more accountable for their pay decisions are needed to address the racial/ethnic wage gaps recently found among planners.
The D^6 R^4 term from three loop maximal supergravity
Creators: name: Basu, Anirban
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the D^6 R^4 term which is the leading contribution in the low momentum expansion of the three loop, four graviton amplitude in maximal supergravity. We calculate the moduli dependent coefficient of this term in 11 dimensional supergravity compactified on T^2. Only diagrams that involve the Mercedes skeleton contribute resulting in a compact expression involving an integral over 6 Schwinger parameters. We express this integral as an integral over the moduli of an auxiliary T^3. This includes an SL(3,Z) invariant integral over the shape moduli of the T^3. We discuss the renormalization of the ultraviolet divergences of this amplitude that arise from the boundaries of moduli space. The renormalized amplitude is simple which is a consequence of the fact that the D^6 R^4 term is BPS.
description: 62 pages, 23 figures, LaTeX
Buying Access One Trip at a Time
Creators: name: Brown, Anne
name: Klein, Nicholas J.
name: Smart, Michael J.
name: Howell, Amanda
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: New transportation options like ride-hail can expand accessibility without the costs of car ownership. Ride-hail’s potential is particularly salient for lower-income and zero-car households. We used interviews and a national (U.S.) survey to examine how and why lower-income travelers in the United States use ride-hail. Survey and interview responses provided a temporal snapshot and thus reflect, in part, travel challenges specific to COVID-19. Findings suggest that lower-income travelers, particularly those without personal cars, use ride-hail in ways distinct from those typically reported in broader travel surveys. Individuals without cars are more likely to use ride-hail, and use it more often, compared with people with cars, particularly to fill spatial and temporal gaps in public transit service and to access medical care and groceries. Costs and price unpredictability remain significant barriers limiting travelers’ use of ride-hail services. This research demonstrates a latent need for car access among lower-income travelers. Substantial gaps in alternative modes pose challenges for travelers seeking reliable and timely transportation. Planners should invest in transit, biking, and walking to provide robust alternatives to car ownership. Such investments, however, take time. In the meantime, cities and agencies should consider subsidizing ride-hail trips to bridge existing gaps in the transportation network.
Hypothesis-generating analysis of the impact of non-damaging metabolic acidosis on the transcriptome of different cell types : integrated stress response (ISR) modulation as general transcriptomic reaction to non-respiratory acidic stress?
Creators: name: Dubourg, Virginie
name: Schulz, Marie-Christin
name: Terpe, Philipp
name: Ruhs, Stefanie
name: Kopf, Michael
name: Gekle, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Extracellular pH is an important parameter influencing cell function and fate. Microenvironmental acidosis accompanies different pathological situations, including inflammation, hypoxia and ischemia. Research focussed mainly on acidification of the tumour micromilieu and the possible consequences on proliferation, migration and drug resistance. Much less is known regarding the impact of microenvironmental acidosis on the transcriptome of non-tumour cells, which are exposed to local acidosis during inflammation, hypoxia, ischemia or metabolic derailment. In the present hypothesis-generating study, we investigated the transcriptional impact of extracellular acidosis on five non-tumour cell types of human and rat origin, combining RNA-Sequencing and extensive bioinformatics analyses. For this purpose, cell type-dependent acidosis resiliences and acidosis-induced transcriptional changes within these resilience ranges were determined, using 56 biological samples. The RNA-Sequencing results were used for dual differential-expression analysis (DESeq and edgeR) and, after appropriate homology mapping, Gene Ontology enrichment analysis (g:Profiler), Ingenuity Pathway Analysis (IPA®), as well as functional enrichment analysis for predicted upstream regulators, were performed. Extracellular acidosis led to substantial, yet different, quantitative transcriptional alterations in all five cell types. Our results identify the regulator of the transcriptional activity NCOA5 as the only general acidosis-responsive gene. Although we observed a species- and cell type-dominated response regarding gene expression regulation, Gene Ontology enrichment analysis and upstream regulator analysis predicted a general acidosis response pattern. Indeed, they suggested the regulation of four general acidosis-responsive cellular networks, which comprised the integrated stress response (ISR), TGF-β signalling, NFE2L2 and TP53. Future studies will have to extend the results of our bioinformatics analyses to cell biological and cell physiological validation experiments, in order to test the refined working hypothesis here.
ХЎЖАЛИК ШАРТНОМАЛАРИНИ ТУЗИШНИНГ ЭРКИНЛИК ПРИНЦИПИ ВА УНИНГ АҲАМИЯТИ
Creators: name: Самарқанд давлат тиббиёт университети Лутфуллаев Мирзохид Салохитдинович
Publisher: name: Zenodo
Year: 2024

description: Ҳар қандай давлат иқтисодиётининг ривожланишида қонунларнинг қатъий ўрнатилганлиги ҳамда тенг ҳуқуқлиликнинг таъминланганлиги муҳим ўрин эгаллайди. Ўзбекистон Республикасининг Конституциясида ҳар бир шахс мулкдор бўлишга ҳақли эканлиги белгиланиб, иқтисодий фаолият, тадбиркорлик ва меҳнат қилиш эркинлиги, мулкдорларнинг тенглиги кафолатлаб қўйилган.
Heme binding to the SARS-CoV-2 spike glycoprotein
Creators: name: Freeman, Samuel L
name: Oliveira, A Sofia F
name: Gallio, Andrea E
name: Rosa, Annachiara
name: Simitakou, Maria K
name: Arthur, Christopher J
name: Mulholland, Adrian J
name: Cherepanov, Peter
name: Raven, Emma L
Publisher: name: The Francis Crick Institute
Year: 2023
Subjects: Biochemistry & Proteomics
Genome Integrity & Repair
Structural Biology & Biophysics
Cell Cycle & Chromosomes

description: No description supplied
The Type IIb SN 2011dh - Two years of observations and modelling of the lightcurves
Creators: name: Ergon, M.
name: Jerkstrand, A.
name: Sollerman, J.
name: Elias-Rosa, N.
name: Fransson, C.
name: Fraser, M.
name: Pastorello, A.
name: Kotak, R.
name: Taubenberger, S.
name: Tomasella, L.
name: Valenti, S.
name: Benetti, S.
name: Helou, G.
name: Kasliwal, M. M.
name: Maund, J.
name: Smartt, S. J.
name: Spyromilio, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present optical and near-infrared (NIR) photometry and spectroscopy as well as modelling of the lightcurves of the Type IIb supernova (SN) 2011dh. Our extensive dataset spans two years, and complemented with Spitzer mid-infrared (MIR) data, we use it to build an optical-to-MIR bolometric lightcurve between days 3 and 732. To model the bolometric lightcurve before day 400 we use a grid of hydrodynamical SN models and a bolometric correction determined with steady-state NLTE modelling. Using this method we find a helium core mass of 3.1 (+0.7-0.4) solar masses for SN 2011dh, consistent within error bars with previous results. We present bolometric and broad-band lightcurves between days 100 and 500 for the Jerkstrand et al. (2014) steady-state NLTE models, and the preferred 12 solar masses (initial mass) model shows a good overall agreement with the observed lightcurves. We find an excess in the K and the MIR bands developing between days 100 and 250, during which an increase in the optical decline rate is also observed. A local origin of the excess is suggested by the depth of the HeI 2.058 micron absorption. Steady-state NLTE models with a modest dust opacity in the core, turned on during this period, reproduce the observed behaviour, but an additional excess in the Spitzer 4.5 micron band remains. CO first-overtone band emission is detected at day 206, and possibly at day 89, and assuming the additional excess to be dominated by CO fundamental band emission, we find fundamental to first-overtone band ratios considerably higher than observed in SN 1987A. This paper concludes our extensive observational and modelling work on SN 2011dh. The results from hydrodynamical modelling, steady-state NLTE modelling, and stellar evolutionary progenitor analysis are all consistent, and suggest an initial mass of 12 solar masses for the progenitor.
description: Accepted for publication in Astronomy and Astrophysics. Significant cut down of the paper as suggested by the referee. The hydrodynamical modelling of the early (before 100 days) lightcurves of SNe 2011dh, 1993J and 2008ax has been moved to a forthcoming paper
title: „Trianon in der Erinnerungskultur am Beispiel der Anthologie Vérző Magyarország von Dezső Kosztolányi und dem Roman Fejtől s lábtól von Andrea Tompa“
Creators: name: Tako-Opra, Emese
Year: 2021

description: Zum Anlass des 100 jährigen Jubiläums des Vertrages von Trianon wurde im Jahr 2020 in Ungarn sehr viel über diesem tragischen Ereignis geredet. In dieser Arbeit präsentiere ich die Auswirkungen des Vertrages von Trianon auf die ungarische Gesellschaft und das Erscheinungsbild dieses Ereignisses in der Literatur zwischen den beiden Weltkriegen und nach der Wende 1989. Die Motivation zu dieser Arbeit basiert auf die geschichtliche Entwicklung der ungarischen Geschichte seit dem Trauma von Trianon. Diese Aufarbeitung ist literarisch in verschiedenen Romanen und Erzählungen beschrieben.
title: Konzept zur Wissensvermittlung von Visualisierungsmethoden in der Sekundarstufe II
Creators: name: Siebert, Anika
Year: 2021

description: Diese Diplomarbeit beschäftigt sich mit dem Thema Visualization Literacy und wie diese in der Sekundarstufe II vermittelt wird. Die Theorie befasst sich mit Datenvisualisierungen; wie diese im österreichischen Lehrplan verankert sind; Visualization Literacy und digitalen Lernspielen. Im nachfolgenden Praxisteil wird sowohl die Seite der Lernenden als auch die der Lehrenden beleuchtet. Die Stärken und Schwächen der Lernenden wird mittels Visualization Literacy Assessment Test evaluiert. Danach werden Lehrkräfte interviewt, um einen besseren Überblick über den Schulalltag zu bekommen. Die daraus entstandenen Erkenntnisse werden daraufhin in ein Lernspielkonzept verpackt und ein Prototyp vorgestellt.
description: This diploma thesis deals with the topic of Visualization Literacy and how it is taught in secondary education second stage. The theoretical part takes on data visualizations; how they are embedded in the Austrian curriculum; visualization literacy and digital educational games. In the following practical part, both the side of the pupils as well as the side of teachers are examined. The strengths and weaknesses of the learners are evaluated using the Visualization Literacy Assessment Test. Additionally, teachers are interviewed to get a better insight of everyday school life. The resulting knowledge is then combined in an educational game concept and a prototype is presented.
title: The Representation of Jewish Immigrant Life by European Immigrant Author Anzia Yezierska and Ludwig Lewisohn
Creators: name: Andric, Tijana
Year: 2021

description: Mehrere Faktoren begünstigten die Einwanderung europäischer Juden in die Vereinigten Staaten im späten 19. und frühen 20. Jahrhundert, wie die Pogrome in Osteuropa, die das Leben der Juden einschränkten. Die Autoren Anzia Yezierska (1880?-1970) und Ludwig Lewisohn (1882-1955) waren polnische bzw. deutsch-jüdische Emigranten, die vor dem Ersten Weltkrieg mit ihren Familien in die USA zogen. Ihre Werke zeichnen sich durch die Suche nach Akkulturation aus und dienen als Beispiele für Autobiografien von Immigranten. Lewisohn und Yezierska machten ihr jüdische Identität zum Hauptaugenmerk ihrer Autobiografien sowie ihrer Romane, die auch autobiografische Spuren aufweisen. Für beide Autoren bleibt das Streben nach Akkulturation erfolglos und wird durch die Akzeptanz ihres wahren jüdischen Selbst ersetzt. In Up Stream (1922) ist Lewisohn zunächst auf der Suche nach seiner neuen amerikanischen Identität. Mehrere Rückschläge in seinem Leben führten jedoch zu seiner endgültigen Erkenntnis, dass er sein jüdisches Erbe niemals aufgeben und ein voll akzeptierter Amerikaner werden kann. Schließlich wird Lewisohn Zionist. Diese Veränderung der Identität spiegelt sich in The Island Within (1928) da der Roman sich um Arthur Levy dreht, der wahre Selbstverwirklichung findet, sobald er seine jüdische Identität annimmt. Yezierska erweitert als Immigrantenautorin das Genre der Immigranten-Autobiographie, indem sie den Einwanderinnen eine Stimme gibt. Der Kern ihrer Werke basiert auf dem Kampf einer jungen jüdischen Frau, die versucht, ihr Erbe und ihr Elternhaus aufzugeben, um ihren Wandel als Amerikanerin zu vollenden, was in Bread Givers (1925) und in ihrer Autobiografie Red Ribbon on a White Horse (1950) zur Geltung kommt. Yezierskas Heldinnen finden Frieden, sobald sie sich als Frauen in der Gesellschaft etabliert haben.
Giant and pigmy dipole resonances in 4He, 16,22O, and 40Ca from chiral nucleon-nucleon interactions
Creators: name: Bacca, S.
name: Barnea, N.
name: Hagen, G.
name: Miorelli, M.
name: Orlandini, G.
name: Papenbrock, T.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We combine the coupled-cluster method and the Lorentz integral transform for the computation of inelastic reactions into the continuum. We show that the bound-state-like equation characterizing the Lorentz integral transform method can be reformulated based on extensions of the coupled-cluster equation-of-motion method, and we discuss strategies for viable numerical solutions. Starting from a chiral nucleon-nucleon interaction at next-to-next-to-next-to-leading order, we compute the giant dipole resonances of 4He, 16,22O and 40Ca, truncating the coupled-cluster equation-of-motion method at the two-particle-two-hole excitation level. Within this scheme, we find a low-lying E1 strength in the neutron-rich 22O nucleus, which compares fairly well with data from [Leistenschneider et al. Phys. Rev. Lett. 86, 5442 (2001)]. We also compute the electric dipole polariziability in 40Ca. Deficiencies of the employed Hamiltonian lead to overbinding, too small charge radii and a too small electric dipole polarizability in 40Ca.
description: 14 pages, 14 figures, published version
An adaptive multi-level simulation algorithm for stochastic biological systems
Creators: name: Lester, Christopher
name: Yates, Christian A.
name: Giles, Michael B.
name: Baker, Ruth E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: Discrete-state, continuous-time Markov models are widely used in the modeling of biochemical reaction networks. Their complexity often precludes analytic solution, and we rely on stochastic simulation algorithms to estimate system statistics. The Gillespie algorithm is exact, but computationally costly as it simulates every single reaction. As such, approximate stochastic simulation algorithms such as the tau-leap algorithm are often used. Potentially computationally more efficient, the system statistics generated suffer from significant bias unless tau is relatively small, in which case the computational time can be comparable to that of the Gillespie algorithm. The multi-level method (Anderson and Higham, Multiscale Model. Simul. 2012) tackles this problem. A base estimator is computed using many (cheap) sample paths at low accuracy. The bias inherent in this estimator is then reduced using a number of corrections. Each correction term is estimated using a collection of paired sample paths where one path of each pair is generated at a higher accuracy compared to the other (and so more expensive). By sharing random variables between these paired paths the variance of each correction estimator can be reduced. This renders the multi-level method very efficient as only a relatively small number of paired paths are required to calculate each correction term. In the original multi-level method, each sample path is simulated using the tau-leap algorithm with a fixed value of $τ$. This approach can result in poor performance when the reaction activity of a system changes substantially over the timescale of interest. By introducing a novel, adaptive time-stepping approach where $τ$ is chosen according to the stochastic behaviour of each sample path we extend the applicability of the multi-level method to such cases. We demonstrate the efficiency of our method using a number of examples.
description: 23 pages
The plucked string: an example of non-normal dynamics
Creators: name: Politzer, David
Publisher: name: arXiv
Year: 2014
Subjects: subject: Popular Physics (physics.pop-ph)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: Motion of a single Fourier mode of the plucked string is an example of transient, free decay of coupled, damped oscillators. It shares the rarely discussed features of the generic case, e.g., possessing a complete set of non-orthogonal eigenvectors and no normal modes, but it can be analyzed and solved analytically by hand in an approximation that is appropriate to musical instruments' plucked strings.
description: 18 pages, 3 figures; revised to include reference to additional examples of transient growth and non-normal dynamics and expanded to include the most general coupling of vertical to horizontal string modes and not just the simplest example presented earlier
Offene Bildung - Open Educational Resources
Creators: name: Hapke, Thomas
name: Rajski, Beate
name: Bieler, Detlev
Publisher: name: Zenodo
Year: 2019
Subjects: #OAWeek
#OAWeek2019
OER
HOOU
Hamburg Open Online University

description: Poster zu Offene Bildung + Open Educational Resources. Überblick und Materialien.
Demazure Modules, Chari-Venkatesh Modules and Fusion Products
Creators: name: Ravinder, Bhimarthi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 17B67, 17B10

description: Let $\mathfrak{g}$ be a finite-dimensional complex simple Lie algebra with highest root $θ$. Given two non-negative integers $m$, $n$, we prove that the fusion product of $m$ copies of the level one Demazure module $D(1,θ)$ with $n$ copies of the adjoint representation ${\rm ev}_0 V(θ)$ is independent of the parameters and we give explicit defining relations. As a consequence, for $\mathfrak{g}$ simply laced, we show that the fusion product of a special family of Chari-Venkatesh modules is again a Chari-Venkatesh module. We also get a description of the truncated Weyl module associated to a multiple of $θ$.
title: Bildungs- und Schulpolitik in Serbien unter k. u. k. Militärverwaltung (1915-1918)
Creators: name: Milanovic, Milan
Year: 2021

description: Diese Diplomarbeit beschäftigt sich mit der Bildungs- und Schulpolitik, welche die Österreichisch-Ungarische Monarchie im Ersten Weltkrieg in ihrem Verwaltungsgebiet in Serbien verfolgte, nach der erfolgreichen Eroberung und Aufteilung des Landes gemeinsam mit Deutschland und Bulgarien im Jahr 1915. Darüber hinaus werden die historischen Hintergründe für eine solche Politik unterstrichen, u.a. durch eine Schilderung imperialistischer Bestrebungen Deutschlands und Österreich-Ungarns auf dem Balkan und der serbisch-habsburgischen Konfliktpunkte im Vorfeld des Ersten Weltkrieges. Der Kriegsverlauf für Serbien, im Zusammenhang mit der Gründung des ersten jugoslawischen Staates und mit dem endgültigen Zusammenbruch der Habsburgermonarchie, ist ein wesentlicher Faktor dieser Arbeit, insbesondere weil die untersuchte k. u. k. Bildungspolitik um eine gänzlich andere Zukunft der betroffenen Gebiete und der dort lebenden Bevölkerung bemüht war. Die äußerst spärlich vorhandene Literatur zur untersuchten Thematik wurde durch Heranziehung zahlreicher Werke in serbischer Sprache ausgeglichen, wenngleich bildungspolitische Fragen auch in der serbischen Historiographie des Ersten Weltkrieges nur am Rande Beachtung fanden.
title: Der Ölpreis als wichtiger Faktor politischer Entscheidungen?
Creators: name: Bohynik, Sebastian
Year: 2021

description: Die vorliegende Masterarbeit beschreibt den Zusammenhang des Freiheitswertes in Petrostaaten mit dem sich verändernden Ölpreis. Der Untersuchungszeitraum erstreckt sich von 2009 bis 2015. Ausgangspunkt des Ganzen ist eine, als petro-politisches Gesetz, aufgestellte Theorie von Thomas Friedman welche besagt, dass der Freiheitswert, laut Freedom House Index, in Petrostaaten steigt wenn der Ölpreis sinkt. Umgekehrt sinkt, laut der Theorie der Freiheitswert sobald der Ölpreis steigt. Dies konnte Friedman anhand einiger Untersuchungsländer bele-gen. In meiner Arbeit ging es nun darum diese Theorie auf den besagten Zeitraum zu überprüfen. Ich konnte nach einer genauen Auflistung und Darstellung in mehre-ren Tabellen die Theorie für den von mir untersuchten Zeitraum wiederlegen und habe in meiner Masterarbeit anschließend versucht Gründe für die Änderung der Gültigkeit der Theorie von Friedman herauszufinden und diese untersucht.
Surface aligned magnetic moments and hysteresis of an endohedral single-molecule magnet on a metal
Creators: name: Westerström, Rasmus
name: Uldry, Anne-Christine
name: Stania, Roland
name: Dreiser, Jan
name: Piamonteze, Cinthia
name: Matsui, Fumihiko
name: Rusponi, Stefano
name: Brune, Harald
name: Yang, Shangfeng
name: Popov, Alexey
name: Büchner, Bernd
name: Delley, Bernard
name: Greber, Thomas
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The interaction between the endohedral unit in the single-molecule magnet Dy$_2$ScN@C$_{80}$ and a rhodium (111) substrate leads to alignment of the Dy 4$f$ orbitals. The resulting orientation of the Dy$_2$ScN plane parallel to the surface is inferred from comparison of the angular anisotropy of x-ray absorption spectra and multiplet calculations in the corresponding ligand field. The x-ray magnetic circular dichroism (XMCD) is also angle dependent and signals strong magnetocrystalline anisotropy. This directly relates geometric and magnetic structure. Element specific magnetization curves from different coverages exhibit hysteresis at a sample temperature of $\sim4$ K. From the measured hysteresis curves we estimate the zero field remanence life-time during x-ray exposure of a sub-monolayer to be about 30 seconds.
description: 5 pages, 4 figures
An evaluation of several combinations of routing and storage location assignment policies for the order batching problem
Creators: name: Bahçeci, Ufuk
name: Öncan, Temel
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: In this work, we address the Order Batching Problem (OBP) and we devise tailor-made Mixed Integer Linear Programming (MILP) formulations of the OBP considering composite, largest gap and optimum routing policies, for the first time. We also introduce a novel picker routing policy named as mixed policy which combines the properties of both midpoint and return routing policies. Then, we perform extensive computational experiments with MILP formulations of the OBP considering several combinations of routing and storage policies under different operating conditions on randomly generated test instances. Finally, we present several managerial insights based on the computational results.
Exploring the spin-orbital ground state of Ba3CuSb2O9
Creators: name: Smerald, Andrew
name: Mila, Frederic
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Motivated by the absence of both spin freezing and a cooperative Jahn-Teller effect at the lowest measured temperatures, we study the ground state of Ba3CuSb2O9. We solve a general spin-orbital model on both the honeycomb and the decorated honeycomb lattice, revealing rich phase diagrams. The spin-orbital model on the honeycomb lattice contains an SU(4) point, where previous studies have shown the existence of a spin-orbital liquid with algebraically decaying correlations. For realistic parameters on the decorated honeycomb lattice, we find a phase that consists of clusters of nearest-neighbour spin singlets, which can be understood in terms of dimer coverings of an emergent square lattice. While the experimental situation is complicated by structural disorder, we show qualitative agreement between our theory and a range of experiments.
description: 12 pages, 9 figures
A systematic literature review exploring uncertainty management and sustainability outcomes in circular supply chains
Creators: name: de Lima, Felipe Alexandre
name: Seuring, Stefan
name: Sauer, Philipp C.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: The circular economy (CE) has inspired the emergence of circular supply chains (CSCs) to reduce the environmental impacts of linear production systems. However, the transition to CSCs faces numerous challenges and uncertainties, which in turn impact the sustainability performance of CSCs. Following a systematic review process, this paper aims to identify the uncertainties that CSCs entail and the uncertainty management strategies which can be used to mitigate them to enhance their sustainability performance. A conceptual framework is proposed under which the current literature on CSCs, including 106 peer-reviewed English journal articles, is analysed and discussed based on CE practices, uncertainty management, and sustainability performance indicators. This framework offers guidance to CE and CSC scholars and supports practitioners and policymakers in being aware of the uncertainties related to the operationalisation and implementation of the CE in order to offer CE-inspired solutions. This paper also proposes a research agenda to investigate the integration of CE practices with supply chain management; the ways in which organisations manage different uncertainties simultaneously; and the effect of multiple uncertainty management strategies on firms’ sustainability performance.
Mitigation strategies against supply disruption risk: a case study at the Ford Motor Company
Creators: name: Sanci, Ece
name: Daskin, Mark S.
name: Hong, Young-Chae
name: Roesch, Steve
name: Zhang, Don
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Supply chains are exposed to different risks, which can be mitigated by various strategies based on the characteristics and needs of companies. In collaboration with Ford, we develop a decision support framework to choose the best mitigation strategy against supply disruption risk, especially for companies operating with a small supplier base and low inventory levels. Our framework is based on a multistage stochastic programming model which incorporates a variety of plausible strategies, including reserving backup capacity from the primary supplier, reserving capacity from a secondary supplier, and holding backup inventory. We reflect disruption risk into the framework through decision makers’ input on the time to recover and the disruption probability. Our results demonstrate that relying on the strategy which is optimal when there is no disruption risk can increase the expected total cost substantially in the presence of disruption risk. However, this increase can be reduced significantly by investing in the mitigation strategy recommended by our framework. Our results also show that this framework removes the burden of estimating the time to recover and the disruption probability precisely since there is often a small loss associated with using another strategy that is optimal in the neighbourhood of the estimated values.
Are my peers impulsive? Normative perceptions of impulsivity and associations with personal impulsivity and alcohol use outcomes
Creators: name: Stamates, A. L.
name: Todaro, S. M.
name: Rothstein, M. C.
name: Sherman, A. L.
name: Nolan, T. J
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Mental Health

description: The present study examined whether individuals perceived their peers’ impulsivity as different from their own impulsivity and if perceptions of peers’ impulsivity moderated the associations between personal impulsivity and alcohol use and consequences. Participants were 291 college student drinkers. An online survey assessed impulsivity, peer norms of impulsivity, and alcohol use. T-tests and hierarchical regressions examined associations. Peer impulsivity (i.e. negative/positive urgency, lack of premeditation/perseverance) norms were generally higher than personal impulsivity, except for sensation seeking. Individuals with greater personal lack of premeditation tended to consume more alcohol, and having higher peer lack of premeditation norms strengthened this relationship. Only greater peer lack of premeditation norms were associated with greater consequences. Findings suggested that individuals generally perceived peer impulsivity to be higher than their own impulsivity. There was some support that peer impulsivity norms (i.e. lack of premeditation) were related to personal alcohol outcomes.
Complementarity and correlations
Creators: name: Maccone, Lorenzo
name: Bruss, Dagmar
name: Macchiavello, Chiara
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We provide an interpretation of entanglement based on classical correlations between measurement outcomes of complementary properties: states that have correlations beyond a certain threshold are entangled. The reverse is not true, however. We also show that, surprisingly, all separable nonclassical states exhibit smaller correlations for complementary observables than some strictly classical states. We use mutual information as a measure of classical correlations, but we conjecture that the first result holds also for other measures (e.g. the Pearson correlation coefficient or the sum of conditional probabilities).
description: Published version (+1 reference)
title: Telemedizin und die Akzeptanz der Konsument*innen
Creators: name: Steinbauer, Maximilian Stephan
Year: 2021

description: Obwohl das Feld der Telemedizin in Österreich im Zeichen der Covid-19-Pandemie zunehmend an Bedeutung gewinnt, sind Nutzungsindikatoren bislang weitgehend unerforscht. Das Ziel dieser Studie war demnach die Darstellung der Akzeptanz von telemedizinischer Behandlung bei österreichischen Konsument*innen. Der theoretische Hintergrund dieser Arbeit umfasste dabei Modelle wie das Technologie-Akzeptanz-Modell, das Verlustaversionsmodell sowie zwei Vertrauensmodelle. Mit Hilfe eines Fragebogens zu Einstellung und Nutzungsmotivation sowie Vorstellung einer interaktiven Telemedizin App wurden 232 Datensätze erhoben und analysiert. Die Annahme, dass Vertrauen sowie Nutzen und Bedienbarkeit der Technologie als zentrale positive sowie wahrgenommene Verluste als zentrale negative Einflussfaktoren auf die Akzeptanz von Telemedizin wirken, konnte gestützt werden. Mit zunehmendem Alter der Proband*innen konnte eine Verringerung von Vertrauen und Akzeptanz sowie ein Anstieg von wahrgenommenem Verlust im Zuge der Telemedizin festgestellt werden. Die Aussagekraft soziodemografischer Einflüsse ist durch die Unterrepräsentation älterer Teilnehmer*innen limitiert, insgesamt konnten die Ergebnisse internationaler Studien jedoch bestätigt werden. Die Vorstellung der Telemedizin App konnte die wahrgenommene Behandlungsqualität steigern, hatte jedoch keinen Einfluss auf die Akzeptanz von Telemedizin. Ein Ausblick für den erfolgreichen Ausbau der Telemedizin in Österreich sowie die Importanz weiterer Untersuchungen im Bereich der Akzeptanzbildung werden abschließend dargestellt.
openTUHH: Services der Bibliothek
Creators: name: Bieler, Detlev
name: Hapke, Thomas
name: Rajski, Beate
Publisher: name: Zenodo
Year: 2018
Subjects: #OAWeek
#OAWeek2018
TU Hamburg
Bibliothek
Open Science
Open Education
openTUHH

description: Plakat zu den Services der Bibliothek der TU Hamburg, die für openTUHH relevant sind. Das Plakat wurde anläßlich der Open Access Week 2018 und der Verabschiedung der Policy für Offenheit in Forschung und Lehre der TU Hamburg erstellt. Die Inhalte von openTUHH finden sich in der Policy.
IceCube events and decaying dark matter: hints and constraints
Creators: name: Esmaili, Arman
name: Kang, Sin Kyu
name: Serpico, Pasquale Dario
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: In the light of the new IceCube data on the (yet unidentified) astrophysical neutrino flux in the PeV and sub-PeV range, we present an update on the status of decaying dark matter interpretation of the events. In particular, we develop further the angular distribution analysis and discuss the perspectives for diagnostics. By performing various statistical tests (maximum likelihood, Kolmogorov-Smirnov and Anderson-Darling tests) we conclude that currently the data show a mild preference (below the two sigma level) for the angular distribution expected from dark matter decay vs. the isotropic distribution foreseen for a conventional astrophysical flux of extragalactic origin. Also, we briefly develop some general considerations on heavy dark matter model building and on the compatibility of the expected energy spectrum of decay products with the IceCube data, as well as with existing bounds from gamma-rays. Alternatively, assuming that the IceCube data originate from conventional astrophysical sources, we derive bounds on both decaying and annihilating dark matter for various final states. The lower limits on heavy dark matter lifetime improve by up to an order of magnitude with respect to existing constraints, definitively making these events---even if astrophysical in origin---an important tool for astroparticle physics studies.
description: 27 pages, 10 figures; v2: references added, clarifications included, matches the version published in JCAP
title: Diskriminierung – Motivation – Lernerfolg
Creators: name: Geiger, Judith Elisabeth
Year: 2021

description: Die vorliegende Arbeit beschäftigt sich mit dem Zusammenhang von Diskriminierung und Motivation und deren Einfluss auf den Lernerfolg bei geflüchteten Erwachsenen in Österreich, die sich im Deutschlernprozess befinden. Es wird gezeigt, dass Diskriminierung die Lernmotiviation beeinflusst und diese wiederum den Lernerfolg bestimmt. Diese interdisziplinäre Überschau gibt Einblicke in die Forschungsergebnisse zu diesem Themenbereich aus Linguistik, Psychologie und Sozialwissenschaften und führt diese unter einer neuen Perspektive zusammen, um schließlich die Möglichkeit zu weiteren empirischen Untersuchungen in diesem Gebiet zu eröffnen. Zentral ist die Frage, wie Sprachenlernen generell funktioniert und wie es durch evtl. Diskriminierungserfahrungen gestört wird. Dabei ist der Aspekt der Motivation und deren Funktionsmechanismen als Bindeglied zwischen Sprachlernprozessen und deren Ergebnissen zu sehen. Schließlich werden Ansätze vorgestellt, wie sich das Lernumfeld der Zielgruppe (nicht) gestalten sollte, damit es zu einem zufriedenstellenden Lernergebnis kommen kann.
description: The present paper deals with the interconnection of discrimination and motivation, and its influence on the success of adult refugees in Austria when learning German. It will be demonstrated that discrimination has a huge impact on the motivation to learn, and this in turn defines the learning outcomes. This interdisciplinary, global view provides insights into scientific research results on this subject drawn from linguistics, psychology and the social sciences and merges them to create a new perspective on the matter with the aim of opening the way for empirical studies in this intersectional area. The key question is how language learning works in general and hence how it can be hindered by the experience of being discriminated against. The aspect of motivation and its functional mechanism serves as a key link between the process of language learning and its results. Finally, this paper will offer ideas on how the learning environment of the target group should (not) be organized, so that a satisfactory result can be reached.