cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Long-term impact of grain legumes and nutrient management practices on soil microbial activity and biochemical properties
Creators: name: Borase, Dnyaneshwar Namdeo
name: Murugeasn, Senthilkumar
name: Nath, Chaitanya Prasad
name: Hazra, Kali Krishna
name: Singh, Sati Shankar
name: Kumar, Narendra
name: Singh, Ummed
name: Praharaj, Chandra Sekhar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Sustainability of rice-wheat rotation is questioned with soil degradation and depleting natural resources. The study aimed to assess the long-term impact of four crop rotations [rice-wheat, rice-wheat-mungbean, rice-chickpea, rice-wheat-rice-chickpea (2-year rotation)], each consisted of three nutrient treatments [control, integrated nutrient management (INM), and chemical fertilizers (RDF)] on soil carbon pools, soil microbial, and biochemical properties. Mungbean inclusion in rice-wheat rotation increased soil organic carbon (SOC) and microbial biomass carbon (MBC) by 17% and 27%. Rice-wheat-mungbean rotation increased soil enzymes activities over rice-wheat rotation, prominent on arylsulfatase (41%), dehydrogenase (38%), and phosphatases (32%). Rice-chickpea rotation had higher alkaline phosphatase (10%), β-glucosidase (13%), and protease (6%) activities over rice-wheat rotation. Rice-wheat-mungbean rotation increased the MBC/SOC and reduced MBC/MBN ratio over rice-wheat rotation, which indicates increased lability of soil carbon and enhanced nitrogen cycling rate. The INM treatment increased SOC (20%), MBC (53%), soil respiration (9%), and enzymes activities over RDF treatment, which was primarily attributed to higher organic matter input through farmyard manure and residues recycling. The higher SOC and microbial activity in legume-inclusive rotations influenced the base-crop (rice) productivity. Thus, the inclusion of grain legume and INM could improve microbial activity and biochemical functions in tropical rice soils.
Tetrasoolium- (MTT) metoodika võimaldab uurida potentsiaalselt aktiivsete ühendite kemosensitiivsust ja -resistentsust
Creators: name: Sak, Katrin
name: Lust, Helen
name: Everaus, Hele
Publisher: name: OÜ Celsius Healthcare
Year: 2015

description: 3-(4,5-dimetüültiasool-2-üül)-2,5-difenüültetrasooliumbromiidi (MTT) kolorimeetriline analüüs on viimase paari aastakümne jooksul leidnud laialdast rakendust nii sünteetiliste kui ka looduslike ainete ja ekstraktide vähivastaste omaduste skriinimisel, et hinnata uuritavate ühendite võimalikku antiproliferatiivset ja tsütotoksilist toimet. Lühiülevaates on välja toodud metoodika põhiprintsiibid, analüüsitud selle eeliseid ja piiranguid ning kirjeldatud ka potentsiaalseid rakendusvõimalusi.Eesti Arst 2015; 94(8):472–477
description: Eesti Arst, September 2015
Transport properties of gases with rotational states
Creators: name: McCourt, Frederick Richard Wayne
Publisher: name: University of British Columbia
Year: 2011

description: Theoretical expressions for the transport coefficients of a single component gas with a nonzero but small local angular momentum density are obtained from a modified Boltzmann equation which takes into account the presence of degenerate internal states (specifically, rotational states). As is to be expected, a number of Onsager reciprocal relations are found connecting the transport coefficients. A linearization of the Boltzmann equation is carried out by means of a perturbation expansion about a local equilibrium state which is characterized by a local temperature, stream velocity and angular momentum density. This perturbation is expressed as a linear combination of the macroscopic gradients of the system, whose coefficients, being tensors, are expanded in terms of irreducible Cartesian tensors made up of the angular momentum pseudovector operator J and the reduced velocity vector W. The transport coefficients are then given by combinations of certain scalar expansion coefficients. Expressions for these expansion coefficients in terms of square bracket integrals are obtained with the aid of an iterative variational procedure based on a scalar product which allows for the lack of time reversal symmetry of the Boltzmann collision operator. Finally, the square bracket integrals are reduced to relative and center-of-mass coordinates and expressed in terms of generalized collision cross sections. The techniques developed for the rotating gas with a nonzero local angular momentum density are utilized to obtain an expression for the change in the thermal conductivity of a gas when placed in a magnetic field. It is shown that at saturation the ratio of the changes in the thermal conductivity with the magnetic field (a) parallel to, and (b) perpendicular to, the temperature gradient is 2/3. This value agrees with the experimental result for paramagnetic gases.
A flexible architecture for modeling and simulation of diffusional association
Creators: name: Haack, Fiete
name: Leye, Stefan
name: Uhrmacher, Adelinde M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Up to now, it is not possible to obtain analytical solutions for complex molecular association processes (e.g. Molecule recognition in Signaling or catalysis). Instead Brownian Dynamics (BD) simulations are commonly used to estimate the rate of diffusional association, e.g. to be later used in mesoscopic simulations. Meanwhile a portfolio of diffusional association (DA) methods have been developed that exploit BD. However, DA methods do not clearly distinguish between modeling, simulation, and experiment settings. This hampers to classify and compare the existing methods with respect to, for instance model assumptions, simulation approximations or specific optimization strategies for steering the computation of trajectories. To address this deficiency we propose FADA (Flexible Architecture for Diffusional Association) - an architecture that allows the flexible definition of the experiment comprising a formal description of the model in SpacePi, different simulators, as well as validation and analysis methods. Based on the NAM (Northrup-Allison-McCammon) method, which forms the basis of many existing DA methods, we illustrate the structure and functioning of FADA. A discussion of future validation experiments illuminates how the FADA can be exploited in order to estimate reaction rates and how validation techniques may be applied to validate additional features of the model.
Post mortem radioloogilised uuringud
Creators: name: Remmer, Sünne
Publisher: name: OÜ Celsius Healthcare
Year: 2015

description: Post mortem kompuutertomograafi a (PMKT) ja magnetresonantstomograafi a (PMMRT) abil on võimalik surma põhjuste ja vigastuste tuvastamiseks saada infot, mida ainult traditsiooniline lahang ei võimalda. Murdude, õhkemboolia ja vaba gaasi visualiseerimiseks kehaõõntes võib PMKT-uuringust saada uus kuldstandard traditsioonilise lahangu asemel. Mõningaid pehmete kudede vigastusi on võimalik kindlaks teha PMMRT-uuringu abil, kuid väliste vigastuste ja siseelundite patoloogiliste muutuste tuvastamisel on traditsiooniline lahang koos välisvaatlusega siiski täpsem meetod. PMMRT sobib neuropatoloogia hindamiseks ja ägeda südamelihaseinfarkti diagnoosimiseks. PMKT ja PMMRT täiendusena on võimalik kasutada intravaskulaarset kontrastainet ning kopsude ventileerimist. Surmajärgsed radioloogilised uuringud võimaldavad teha kolmemõõtmelisi rekonstruktsioone, mille abil saab vigastusi selgemalt visualiseerida.Eesti Arst 2015; 94(8):478–482
description: Eesti Arst, September 2015
Encouraging authors to use and cite data in public repositories; A publisher perspective
Creators: name: Hunter, Christopher
name: Molcrette, Bastien
name: Fan, Yannan
name: Tuli, Mary Ann
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Biocuration
subject: Data Curation
subject: Publishing

description: The poster to be presented at Biocuration 2025 meeting in Kansas city, USA.

Encouraging authors to use and cite data in public repositories; a publisher perspective.

Chris Hunter1, Bastien Molcrette1, Yannan Fan1, Mary Ann Tuli1

1- GigaDB, GigaScience Press, Hong Kong.

GigaScience Press publishes two journals; GigaScience and GigaByte, both have extremely high standards for transparency and reproducibility. In order to maintain these standards we have a team of data curators (biocurators) whose job is to ensure the manuscripts' are as transparent and reproducible as possible prior to publication.

Whilst we do have GigaDB, our own repository to host data associated with GigaScience Press articles, we try to use that only for data that do not have a natural home in a suitable stable public repository such as the INSDC. GigaDB biocurators act as an interpretation layer between the often-verbose standards of FAIR data, and time-pressured authors, who require succinct and pertinent guidance specific to theirmanuscript. We accomplish this by scanning the manuscript prior to peer-review andinstructing the submitting author(s) how to make their data available either privately whilst under peer-review, or directly open. This ensures reviewers can spend their time reviewing the article rather than hunting the data. Collecting the data at this stage ensures that if the manuscript passes peer-review we can proceed straight away with the publication process.

Here we present a summary of the variety of different repositories that our biocurators recommend to authors, and how we ensure those data are suitably cited and linked from the journal articles and, where appropriate, from GigaDB datasets.
Is the nature of magnetic order in copper-oxides and in iron-pnictides different?
Creators: name: Manousakis, E.
name: Ren, J.
name: Meng, S.
name: Kaxiras, E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We use the results of first-principles electronic structure calculations and a strong coupling perturbation approach, together with general theoretical arguments, to illustrate the differences in super-exchange interactions between the copper-oxides and iron-pnictides. We show that the two magnetic ground states can be understood in a simple manner within the same theoretical foundation. Contrary to the emerging view that magnetic order in the iron-pnictides is of itinerant nature, we argue that the observed magnetic moment is small because of frustration introduced by the electrons of the Fe orbitals as they compete to impose their preferred magnetic ordering.
description: 5 pages, 5 figures
A New Class of N=2 Topological Amplitudes
Creators: name: Antoniadis, I.
name: Hohenegger, S.
name: Narain, K. S.
name: Sokatchev, E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We describe a new class of N=2 topological amplitudes that compute a particular class of BPS terms in the low energy effective supergravity action. Specifically they compute the coupling F^2(λλ)^{g-2}(dϕ)^2 where F, λand ϕare gauge field strengths, gaugino and holomorphic vector multiplet scalars. The novel feature of these terms is that they depend both on the vector and hypermultiplet moduli. The BPS nature of these terms implies that they satisfy a holomorphicity condition with respect to vector moduli and a harmonicity condition as well as a second order differential equation with respect to hypermultiplet moduli. We study these conditions explicitly in heterotic string theory and show that they are indeed satisfied up to anomalous boundary terms in the world-sheet moduli space. We also analyze the boundary terms in the holomorphicity and harmonicity equations at a generic point in the vector and hyper moduli space. In particular we show that the obstruction to the holomorphicity arises from the one loop threshold correction to the gauge couplings and we argue that this is due to the contribution of non-holomorphic couplings to the connected graphs via elimination of the auxiliary fields.
description: 70 pages
Võõrana omade hulgas: Gustav Piers von Bunge ja baltisaksa karskustöö
Creators: name: Kalling, Ken
name: Tammiksaar, Erki
Publisher: name: OÜ Celsius Healthcare
Year: 2015

description: 19. sajandi lõpukümnendil kogus eesti ühiskonnas hoogu karskusliikumine. Sama ei saa öelda kohaliku eliidi – baltisakslaste – kohta. Sakste tõrksus on tähelepanuväärne kas või seetõttu, et nende hulgast võrsus üks eelmise sajandivahetuse juhtivaid meditsiinilise karskustöö propageerijaid Gustav Piers von Bunge, kes suurema osa oma elust veetis Šveitsis Baseli ülikoolis. Bunge püüdis ka oma kodumaal progressiivseid tervishoiuideid propageerida, tuues baltisakslastele eeskujuks eestlasi ja lätlasi. Esialgu võtsid karskusidee omaks baltisaksa naised. Esimese maailmasõja eelõhtul hakkas siiski ka kohalik saksa soost arstkond teemale enam tähelepanu pöörama, jäädes siiski Bungega võrreldes mõõdukamale seisukohale, mille kohaselt on alkoholitarvitamise üle otsustamine iga indiviidi isiklik valik. Baltisakslaste tõrksus karskustöö suhtes lähtus majanduslikust kahjulikkusest nende ringkonnale (riiklik viinamonopol kaotas kõrtsidepidamise õiguse), eriti aga karskusliikumise politiseeritusest. Siin oli oluline roll eesti karskusliikumisel.Eesti Arst 2015; 94(8):484–489
description: Eesti Arst, September 2015
Imprint of galaxy clustering in the cosmic gamma-ray background
Creators: name: Ando, Shin'ichiro
name: Pavlidou, Vasiliki
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Star-forming galaxies are predicted to contribute considerably to the cosmic gamma-ray background (CGB) as they are confirmed gamma-ray emitters and are the most numerous population of gamma-ray sources, although individually faint. Even though the Fermi Gamma-ray Space Telescope will be able to resolve few star-forming galaxies individually, their fractional contribution to the CGB should become far more significant than it was for past measurements of the CGB as many of the brighter, formerly unresolved sources will be resolved out. Thus, the clustering feature of galaxies imprinted on the CGB might be detectable by Fermi. In anticipation of such measurements, we calculate the predicted angular auto-power and cross-power spectra of the CGB from normal galaxies. We find that the amplitude of the auto-power spectrum is smaller than that for other sources such as blazars and dark-matter annihilation; the shape is also characteristic. We also show that the cross-power spectrum with galaxy surveys features larger amplitude. Fermi should be able to detect the correlation signature in both the auto-power and cross-power spectra at angular scales of ~1-10 deg after 5-yr of operation. Such a detection would be valuable in confirming the level of the star-forming galaxy contribution to the CGB, and more importantly, in serving as a tool in the effort to discriminate between possible origins of the CGB.
description: 7 pages, 6 figures; accepted to MNRAS
Effective detection of rare variants in pooled DNA samples using Cross-pool tailcurve analysis
Creators: name: Niranjan, Tejasvi S
name: Adamczyk, Abby
name: Bravo, Héctor Corrada
name: Taub, Margaret A
name: Wheelan, Sarah J
name: Irizarry, Rafael
name: Wang, Tao
Publisher: name: Springer Nature
Year: 2011
Subjects: Rare Variant
Variant Calling
Variant Call
Base Call
False Positive Call

description: Sequencing targeted DNA regions in large samples is necessary to discover the full spectrum of rare variants. We report an effective Illumina sequencing strategy utilizing pooled samples with novel quality (Srfim) and filtering (SERVIC4E) algorithms. We sequenced 24 exons in two cohorts of 480 samples each, identifying 47 coding variants, including 30 present once per cohort. Validation by Sanger sequencing revealed an excellent combination of sensitivity and specificity for variant detection in pooled samples of both cohorts as compared to publicly available algorithms.
BlenX-based compositional modeling of complex reaction mechanisms
Creators: name: Zámborszky, Judit
name: Priami, Corrado
Publisher: name: arXiv
Year: 2010
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Molecular interactions are wired in a fascinating way resulting in complex behavior of biological systems. Theoretical modeling provides a useful framework for understanding the dynamics and the function of such networks. The complexity of the biological networks calls for conceptual tools that manage the combinatorial explosion of the set of possible interactions. A suitable conceptual tool to attack complexity is compositionality, already successfully used in the process algebra field to model computer systems. We rely on the BlenX programming language, originated by the beta-binders process calculus, to specify and simulate high-level descriptions of biological circuits. The Gillespie's stochastic framework of BlenX requires the decomposition of phenomenological functions into basic elementary reactions. Systematic unpacking of complex reaction mechanisms into BlenX templates is shown in this study. The estimation/derivation of missing parameters and the challenges emerging from compositional model building in stochastic process algebras are discussed. A biological example on circadian clock is presented as a case study of BlenX compositionality.
ANTECEDENT-ANAPHOR RELATIONS IN THE OLU DIALECT OF IGBO
Creators: name: MMADIKE, BENJAMIN IFEANYI
Publisher: name: Zenodo
Year: 1998
Subjects: ANTECEDENT
ANAPHOR
IGBO

description: A Ph.D Thesis submitted to the Department of Linguistics and African Languages, University of Ibadan, Ibadan, Nigeria.
X-ray follow-up observations of unidentified VHE gamma-ray sources
Creators: name: Pühlhofer, Gerd
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A large fraction of the recently discovered Galactic Very High Energy (VHE) source population remains unidentified to date. VHE gamma-ray emission traces high energy particles in these sources, but for example in case of hadronic processes also the gas density at the emission site. Moreover, the particles have sufficiently long lifetimes to be able to escape from their acceleration sites. Therefore, the gamma-ray sources or at least the areas of maximum surface brightness are in many cases spatially offset from the actual accelerators. A promising way to identify the objects in which the particles are accelerated seems to be to search for emission signatures of the acceleration process (like emission from shock-heated plasma). Also the particles themselves (through primary or secondary synchrotron emission) can be traced in lower wavebands. Those signatures are best visible in the X-ray band, and current X-ray observatories are well suited to conduct such follow-up observations. Some aspects of the current status of these investigations are reviewed.
description: 4 pages, 1 figure, Proceedings of the 4th Heidelberg International Symposium on High Energy Gamma-Ray Astronomy, July 7-11, 2008, Heidelberg, Germany
Statiinid ja ateroskleroos
Creators: name: Hedman, Anu
name: Ristimäe, Tiina
Publisher: name: OÜ Celsius Healthcare
Year: 2007

description: Et südame-veresoonkonnahaigused (SVH) on juhtiv surmapõhjus USAs ja Euroopas, pööratakse modifitseeritavate riskitegurite (eeskätt arteriaalse hüpertensiooni ja düslipideemia) mõjutamisele palju tähelepanu. Kliiniliselt enim kasutatud ravimirühmaks lipiidide mõjustamisel on vaieldamatult 3-hüdroksü-3-metüülglutarüül-koensüüm A reduktaasi inhibiitorid ehk statiinid, mis võlgnevad oma ainulaadse koha düslipideemiate farmakoteraapias peamiselt jõulisele LDL-kolesterooli sisaldust alandavale toimele. Statiinid vähendavad relatiivset riski SVH tekkes 24–37% ja nende prognoosi parandav toime ei sõltu uuritavate vanusest, soost, südame isheemiatõve või teiste kaasuvate haiguste olemasolust (1). Riigiti on statiinide kasutamine väga erinev. Kuigi Eestis on suremus SVHsse Euroopa suuremaid, kasutatakse meil statiine sekundaarses profülaktikas umbes 10 korda vähem kui Põhjamaades (2, 3) (vt jn 1).


Eesti Arst 2007; 86 (3): 157–160
description: Eesti Arst, Märts 2007
Accurate and fast estimation of taxonomic profiles from metagenomic shotgun sequences
Creators: name: Liu, Bo
name: Gibbons, Theodore
name: Ghodsi, Mohammad
name: Treangen, Todd
name: Pop, Mihai
Publisher: name: Springer Nature
Year: 2011
Subjects: Metagenomic Sequence
Metagenomic Study
Taxonomic Classifier
Good Classification Result
Taxonomic Profile

description: A major goal of metagenomics is to characterize the microbial composition of an environment. The most popular approach relies on 16S rRNA sequencing, however this approach can generate biased estimates due to differences in the copy number of the gene between even closely related organisms, and due to PCR artifacts. The taxonomic composition can also be determined from metagenomic shotgun sequencing data by matching individual reads against a database of reference sequences. One major limitation of prior computational methods used for this purpose is the use of a universal classification threshold for all genes at all taxonomic levels. We propose that better classification results can be obtained by tuning the taxonomic classifier to each matching length, reference gene, and taxonomic level. We present a novel taxonomic classifier MetaPhyler (http://metaphyler.cbcb.umd.edu), which uses phylogenetic marker genes as a taxonomic reference. Results on simulated datasets demonstrate that MetaPhyler outperforms other tools commonly used in this context (CARMA, Megan and PhymmBL). We also present interesting results by analyzing a real metagenomic dataset. We have introduced a novel taxonomic classification method for analyzing the microbial diversity from whole-metagenome shotgun sequences. Compared with previous approaches, MetaPhyler is much more accurate in estimating the phylogenetic composition. In addition, we have shown that MetaPhyler can be used to guide the discovery of novel organisms from metagenomic samples.
Galaxy Satellites and the Weak Equivalence Principle
Creators: name: Keselman, J. A.
name: Nusser, A.
name: Peebles, P. J. E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Numerical simulations of the effect of a long-range scalar interaction (LRSI) acting only on nonbaryonic dark matter, with strength comparable to gravity, show patterns of disruption of satellites that can agree with what is seen in the Milky Way. This includes the symmetric Sagittarius stellar stream. The exception presented here to the Kesden and Kamionkowski demonstration that an LRSI tends to produce distinctly asymmetric streams follows if the LRSI is strong enough to separate the stars from the dark matter before tidal disruption of the stellar component, and if stars dominate the mass in the luminous part of the satellite. It requires that the Sgr galaxy now contains little dark matter, which may be consistent with the Sgr stellar velocity dispersion, for in the simulation the dispersion at pericenter exceeds virial. We present other examples of simulations in which a strong LRSI produces satellites with large mass-to-light ratio, as in Draco, or free streams of stars, which might be compared to "orphan" streams.
description: 14 pages, accepted for publication in PRD
Kathroperla
Creators: name: Stark, Bill P.
name: Kondratieff, Boris C.
name: Verdone, Chris J.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Chloroperlidae
Kathroperla

description: Preliminary Key to Nearctic Kathroperla Species 1 Lateral pronotal margin of adults usually entirely yellow; female subgenital plate usually reaching posterior margin of sternum 9 (Fig. 4 in Stark & Surdick 1987); egg collar absent and chorionic striations absent (Figs. 20-25); dorsal margin of epiproct usually bicolored with a black anterior band adjacent to a dark brown band (Fig. 1 in Stark & Surdick 1987); basal male cercal segments about 3 times long as wide ………………………………………….. K. takhoma 1’ Lateral pronotal margins of adults with black pigment extending at least a third of the margin length, but often completely dark (Fig. 15); egg collar present, chorionic striations present although sometimes indistinct (Figs. 1-6, 9-14); dorsal margin of epiproct narrow and black; basal male cercal segments about 2-2.5 times long as wide ………………………………...…… 2 2 Dorsolateral margin of male epiproct slanted conspicuously caudad (Fig. 16); egg chorion covered with fine bead-like tubercles poorly organized into striations (Figs. 9-14) ………………………….………………. K. siskiyou 2’ Dorsal margin of male epiproct almost straight; egg chorion covered with thick tubercles organized into well-developed longitudinal striations (Figs. 1-6) …………....….…... K. perdita
description: Published as part of Stark, Bill P., Kondratieff, Boris C. & Verdone, Chris J., 2015, Kathroperla Siskiyou, A New Stonefly Species From California And Oregon, U. S. A. (Plecoptera: Chloroperlidae), pp. 92-103 in Illiesia 11 (8) on page 101, DOI: 10.5281/zenodo.4760976
description: {"references": ["Stark, B. P. & R. F. Surdick. 1987. A new Kathroperla species from western North America (Plecoptera: Chloroperlidae). Proceedings of the Entomological Society of Washington, 89: 527 - 531."]}
DNA binding activities of the Herves transposase from the mosquito Anopheles gambiae
Creators: name: Kahlon, Amandeep S
name: Hice, Robert H
name: O'Brochta, David A
name: Atkinson, Peter W
Publisher: name: Springer Nature
Year: 2011
Subjects: Binding Motif
Terminal Inverted Repeat
Specific Competitor
Herves Element
Transposase Binding

description: Determining the mechanisms by which transposable elements move within a genome increases our understanding of how they can shape genome evolution. Class 2 transposable elements transpose via a 'cut-and-paste' mechanism mediated by a transposase that binds to sites at or near the ends of the transposon. Herves is a member of the hAT superfamily of class 2 transposons and was isolated from Anopheles gambiae, a medically important mosquito species that is the major vector of malaria in sub-Saharan Africa. Herves is transpositionally active and intact copies of it are found in field populations of A gambiae. In this study we report the binding activities of the Herves transposase to the sequences at the ends of the Herves transposon and compare these to other sequences recognized by hAT transposases isolated from other organisms. We identified the specific DNA-binding sites of the Herves transposase. Active Herves transposase was purified using an Escherichia coli expression system and bound in a site-specific manner to the subterminal and terminal sequences of the left and right ends of the element, respectively, and also interacted with the right but not the left terminal inverted repeat. We identified a common subterminal DNA-binding motif (CG/AATTCAT) that is critical and sufficient for Herves transposase binding. The Herves transposase binds specifically to a short motif located at both ends of the transposon but shows differential binding with respect to the left and right terminal inverted repeats. Despite similarities in the overall structures of hAT transposases, the regions to which they bind in their respective transposons differ in sequence ensuring the specificity of these enzymes to their respective transposon. The asymmetry with which the Herves terminal inverted repeats are bound by the transposase may indicate that these differ in their interactions with the enzyme.
IC10: the history of the nearest starburst galaxy through its Planetary Nebula and HII region populations
Creators: name: Magrini, Laura
name: Goncalves, Denise R.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report the results of spectroscopic observations, obtained with the Gemini North Multi-Object Spectrograph, of 9 planetary nebulae (PNe) and 15 \hii\ regions located in the 5.5\arcmin $\times$5.5\arcmin inner region of the nearby starburst galaxy IC10. Twelve new candidate PNe have been discovered during our pre-imaging phase. Nine of them have been spectroscopically confirmed. The direct availability of the electron temperature diagnostics in several nebulae allowed an accurate determination of the metallicity map of IC10 at two epochs: the present-time from \hii regions and the old/intermediate-age from PNe. We found a non-homogeneous distribution of metals at both epochs, but similar average abundances were found for the two populations. The derived age-metallicity relation shows a little global enrichment interpreted as the loss of metals by SN winds and to differential gas outflows. Finally, we analyzed the production of oxygen --through the third dredge-up-- in the chemical abundance patterns of the PN populations belonging to several dwarf irregular galaxies. We found that the third dredge-up of oxygen is a metallicity dependent phenomenon occurring mainly for 12+$\log$(O/H)$\leq$7.7 and substantially absent in IC10 PNe.
description: 14 pages, 4 figures, 7 tables, accepted for publication by MNRAS
HIV/AIDSi temaatikaga seotud teadmised ja hoiakud Eestis täiskasvanute hulgas
Creators: name: Lai, Karmen
name: Tarik, Kristi
Publisher: name: OÜ Celsius Healthcare
Year: 2007
Subjects: HIV, AIDS, HIV-positiivne inimene, hoiakud

description: HI-viirusega nakatumise plahvatuslik kasv algas 2000. a narkomaanide seas. Vaatamata HIV-nakkuse ennetamisele on viimastel aastatel diagnoositud aastas keskmiselt 600 uut juhtu, millest suurema osa moodustavad mittenarkomaanide nakatumised. Ennetus  meetmete tõhustamise ning riigi poolt HIV-positiivsete peale kasutatavate üha kasvavate ravi summade kõrval tuleb vaadata ka viiruse/haiguse problemaatika inimlikku poolt. Artiklis on analüüsitud Eestis elavate täiskasvanute teadmisi ja hoiakuid seoses HIV/AIDSiga, et selgitada välja, kas ühiskonna liikmed on valmis toetama ja aitama HIV-positiivset inimest.


Eesti Arst 2007; 86 (2): 88–93
description: Eesti Arst, Veebruar 2007
Constraining reionization using 21 cm observations in combination with CMB and Lyman-alpha forest data
Creators: name: Pritchard, Jonathan R.
name: Loeb, Abraham
name: Wyithe, J. Stuart B.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this paper, we explore the constraints on the reionization history that are provided by current observations of the Lyman-alpha forest and the CMB. Rather than using a particular semi-analytic model, we take the novel approach of parametrizing the ionizing sources with arbitrary functions, and perform likelihood analyses to constrain possible reionization histories. We find model independent conclusions that reionization is likely to be mostly complete by z=8 and that the IGM was 50% ionized at z=9-10. Upcoming low-frequency observations of the redshifted 21 cm line of neutral hydrogen are expected to place significantly better constraints on the hydrogen neutral fraction at 6
description: 15 pages, 16 figures, submitted to MNRAS
Non-universal finite size scaling of rough surfaces
Creators: name: Mandal, Pradipta Kumar
name: Jana, Debnarayan
Publisher: name: arXiv
Year: 2009
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We demonstrate the non-universal behavior of finite size scaling in (1+1) dimension of a nonlinear discrete growth model involving extended particles in generalized point of view. In particular, we show the violation of the universal nature of the scaling function corresponding to the height fluctuation in (1+1) dimension. The 2nd order moment of the height fluctuation shows three distinct crossover regions separated by two crossover time scales namely, tx1 and tx2. Each regime has different scaling property. The overall scaling behavior is postulated with a new scaling relation represented as the linear sum of two scaling functions valid for each scaling regime. Besides, we notice the dependence of the roughness exponents on the finite size of the system. The roughness exponents corresponding to the rough surface is compared with the growth rate or the velocity of the surface.
description: 15 pages, 10 figures
Types for BioAmbients
Creators: name: Capecchi, Sara
name: Troina, Angelo
Publisher: name: arXiv
Year: 2010
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Logic in Computer Science (cs.LO)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences
subject: F.3.3; J.3; F.1.2

description: The BioAmbients calculus is a process algebra suitable for representing compartmentalization, molecular localization and movements between compartments. In this paper we enrich this calculus with a static type system classifying each ambient with group types specifying the kind of compartments in which the ambient can stay. The type system ensures that, in a well-typed process, ambients cannot be nested in a way that violates the type hierarchy. Exploiting the information given by the group types, we also extend the operational semantics of BioAmbients with rules signalling errors that may derive from undesired ambients' moves (i.e. merging incompatible tissues). Thus, the signal of errors can help the modeller to detect and locate unwanted situations that may arise in a biological system, and give practical hints on how to avoid the undesired behaviour.
Alzheimeri tõve ravi memantiiniga Eestis: farmakoökonoomiline hindamine
Creators: name: Vähi, Mare
name: Braschinsky, Mark
name: Kirsimägi, Ülle
Publisher: name: OÜ Celsius Healthcare
Year: 2007
Subjects: memantiin, Alzheimeri tõbi, dementsus, farmakoökonoomika

description: Alzheimeri tõbi (AT) on neurodegeneratiivne haigus, mille süvenedes nõrgenevad progresseeruvalt patsientide kognitiivsed ja funktsionaalsed võimed ning kasvab hooldus  sõltuvus. Eestis on AT raviks registreeritud 4 ravimit: memantiin, donepesiil, galantamiin, rivastigmiin. Töös on analüüsitud nimetatud nelja ravimi tegelikku kasutamist, AT-patsientidega seotud tervishoiukulutusi Eestis 2004. aastal ning prognoositud muutusi Eesti Haigekassa (EHK) tervishoiukulutustes AT-patsientidele juhul, kui memantiin arvatakse 75% soodustusmääraga ravimite nimekirja. Analüüsil kasutati EHK retseptide, raviarvete ja ajutise töövõimetuse hüvitiste andmebaasi. Selgus, et memantiini kasutamine vähendab märkimisväärselt kulusid ja lükkab edasi aega, kui patsient vajab pidevat hooldust ning järelevalvet.


Eesti Arst 2007; 86 (2): 94–99
description: Eesti Arst, Veebruar 2007
Väljavaated Eesti rahvastiku tervise parandamiseks
Creators: name: Kaasik, Ain-Elmar
Publisher: name: OÜ Celsius Healthcare
Year: 2007
Subjects: rahvatervis, tervisepoliitika, arstiabi korraldus

description: Eesti rahva tervisenäitajad on muret tekitavad: Eesti inimeste keskmine eeldatav sünnieluiga on lühem isegi euroliidu uute liikmesmaade keskmisest. Lubamatult suur on erinevus keskmise eluea pikkuses meeste-naiste ja erinevatesse sotsiaalsetesse rühmadesse kuuluvate inimeste vahel. Kui euroliidu maades on suremus enne 65. eluaastat 30% üldsuremusest, siis Eestis on selle osakaal 55%. Eesti tõsisemaks terviseprobleemiks on vigastused, alkoholism ja väär terviskäitumine. Rahva terviseseisundi parandamiseks on vaja rakendada ja piisavalt rahastada rahva terviseprogramme, samuti leida lisaraha arstiabi osutamise süsteemile.


Eesti Arst 2007; 86 (2): 100–109
description: Eesti Arst, Veebruar 2007
Global discourses and experiential speculation: Secondary and tertiary graduate Malawians dissect the HIV/AIDS epidemic
Creators: name: Myroniuk, Tyler W
Publisher: name: Springer Nature
Year: 2011
Subjects: Male Circumcision
Sexual Network
Civic Education
Condom Usage
Experiential Speculation

description: Since the beginning of the HIV/AIDS epidemic, the perspectives of secondary and tertiary school graduates in sub-Saharan Africa regarding the effectiveness of government and international HIV/AIDS policies and programmes have not been thoroughly examined. When extensive monetary aid is directed toward "development" in a country like Malawi, it is the educated elites - secondary and tertiary graduates who are heavily involved and influential in the domestic re-distribution and implementation of millions of dollars worth of aid - on whom international expectations fall to decrease the transmission of HIV. Many Malawian jobs related to public health and HIV/AIDS are created as a direct result of this funding and are occupied by the few secondary and tertiary graduates. Thus, it is a practical venture to understand their perspectives on highly contentious and heavily funded HIV/AIDS issues that affect their nation. Qualitative data was collected in this study in efforts to discover in-depth perspectives on the HIV/AIDS epidemic. Thirty-eight secondary and tertiary graduate Malawians took part in semi-structured interviews. Data was analysed using an early grounded theory approach and subsequent themes of "global discourses" and "experiential knowledge of HIV/AIDS" emerged. This group of Malawians frequently responded to questions regarding healthcare and access to medicine, sexual behaviours and methods of reducing the spread of HIV/AIDS by citing and explaining the widespread, international and "proper" responses. The secondary and tertiary graduate Malawians also discussed these same topics in terms of what they perceive or have experienced. Experiential responses, such as the counter-productivity of circumcision and condoms, the overestimation of HIV/AIDS prevalence, and calls for more authoritarian policing of commercial sex work, were remarkably divergent from the HIV/AIDS discourse. The opinions of this group of secondary and tertiary graduate Malawians do not always coincide with the current literature and policies. They give deeper insight into what is perceived and what may be taking place, and hint at what the future holds for their people. The widespread and divergent perspectives must be seriously considered because these experiences describe the potential positive and negative consequences that occur on the ground throughout Malawi as a result of HIV/AIDS policies.
Viiruslik müokardiit, diagnoosimise ja ravi võimalused praegusajal
Creators: name: Lamp, Kristin
name: Sõgel, Vello
Publisher: name: OÜ Celsius Healthcare
Year: 2007
Subjects: müokardiit, magnetresonantstomograafia, endomüokardiaalne biopsia

description: Viiruslik müokardiit on müokardi põletikuline kahjustus. Haiguse diagnoosimine võib osutuda raskeks, kuna see võib kulgeda asümptomaatiliselt või raskematel juhtudel põhjustada müotsüütide ulatuslikku nekroosi ja südamepuudulikkust. Müokardiidi diagnoosimisel arvestatakse kliinilist leidu ja laboratoorseid analüüse. Diagnoosi kinnitab müokardi biopsia leid.Magnetresonatstomograafia leid on samuti informatiivne kinnitamaks müokardiidi diagnoosi.

Eesti Arst 2007; 86 (2): 133–140
description: Eesti Arst, Veebruar 2007
Hidden MeV-Scale Dark Matter in Neutrino Detectors
Creators: name: Kile, Jennifer
name: Soni, Amarjit
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The possibility of direct detection of light fermionic dark matter in neutrino detectors is explored from a model-independent standpoint. We consider all operators of dimension six or lower which can contribute to the interaction $\bar{f} p \to e^+ n$, where $f$ is a dark Majorana or Dirac fermion. Constraints on these operators are then obtained from the $f$ lifetime and its decays which produce visible $γ$ rays or electrons. We find one operator which would allow $\bar{f} p \to e^+ n$ at interesting rates in neutrino detectors, as long as $m_f \lesssim m_π$. The existing constraints on light dark matter from relic density arguments, supernova cooling rates, and big-bang nucleosynthesis are then reviewed. We calculate the cross-section for $\bar{f} p \to e^+ n$ in neutrino detectors implied by this operator, and find that Super-K can probe the new physics scale $Λ$ for this interaction up to ${\cal O}(100 {TeV})$
description: 17 pages, 2 figures; v2: added reference, fixed typos, small changes in wording
Tsöliaakia – kliiniline kameeleon
Creators: name: Ress, Krista
name: Uibo, Oivi
Publisher: name: OÜ Celsius Healthcare
Year: 2007
Subjects: tsöliaakia, tekkemehhanismid, esinemissagedus, kliiniline väljendus, diagnoosimine

description: Tsöliaakia on mitmeteguriline pärilik krooniline haigus, mille korral nisu-, rukki-, odra- ja võimalik, et ka kaeravalkude poolt vallandatavad ning tsöliaakia autoantigeeni – koe transglutaminaasi – vastu tekkivad autoimmuunreaktsioonid põhjustavad peensoole limaskesta kahjustuse. Seda autoimmuunset haigust esineb kuni 2%-l rahvastikust. Haigusele iseloomulikuks histoloogiliseks leiuks on peensoole limaskesta
hattude atroofia ja krüptide hüperplaasia, millest tulenevalt on tsöliaakia klassikaliseks sümptomiks malabsorptsiooni sündroom.


Eesti Arst 2007; 86 (2): 121–132
description: Eesti Arst, Veebruar 2007
Genomic risk prediction of coronary artery disease in women with breast cancer: a prospective cohort study.
Creators: name: Liou, Lathan
name: Kaptoge, Stephen
name: Dennis, Joe
name: Shah, Mitul
name: Tyrer, Jonathan
name: Inouye, Michael
name: Easton, Douglas F
name: Pharoah, Paul D P
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Breast cancer
Cardiovascular disease
coronary artery disease
Coronary Heart Disease
Search
Polygenic Risk Score

description: Funder: Wellcome Trust
description: BackgroundAdvancements in cancer therapeutics have resulted in increases in cancer-related survival; however, there is a growing clinical dilemma. The current balancing of survival benefits and future cardiotoxic harms of oncotherapies has resulted in an increased burden of cardiovascular disease in breast cancer survivors. Risk stratification may help address this clinical dilemma. This study is the first to assess the association between a coronary artery disease-specific polygenic risk score and incident coronary artery events in female breast cancer survivors.MethodsWe utilized the Studies in Epidemiology and Research in Cancer Heredity prospective cohort involving 12,413 women with breast cancer with genotype information and without a baseline history of cardiovascular disease. Cause-specific hazard ratios for association of the polygenic risk score and incident coronary artery disease (CAD) were obtained using left-truncated Cox regression adjusting for age, genotype array, conventional risk factors such as smoking and body mass index, as well as other sociodemographic, lifestyle, and medical variables.ResultsOver a median follow-up of 10.3 years (IQR: 16.8) years, 750 incident fatal or non-fatal coronary artery events were recorded. A 1 standard deviation higher polygenic risk score was associated with an adjusted hazard ratio of 1.33 (95% CI 1.20, 1.47) for incident CAD.ConclusionsThis study provides evidence that a coronary artery disease-specific polygenic risk score can risk-stratify breast cancer survivors independently of other established cardiovascular risk factors.
Small arms in post-conflict situation - Solomon Islands
Creators: name: Hegarty, David
Publisher: name: Canberra, ACT: State, Society and Governance in Melanesia (SSGM) Program, The Australian National University
Year: 2001
Subjects: International Peace Monitoring Team
Townsville Peace Agreement
disarmament

description: The International Peace Monitoring Team is an unarmed and neutral organisation that was established at the request of the signatories to the Townsville Peace Agreement (TPA) to monitor and assist the peace process in the Solomon Islands with particular reference to the provinces of Guadalcanal and Malaita. This paper discusses the role the IPMT played in this region.
Krüptogeenne organiseeruv pneumoonia ehk peit-tekkene organiseeruv kopsupõletik
Creators: name: Altraja, Alan
name: Püttsepp, Enn
name: Lapidus, Natalia
Publisher: name: OÜ Celsius Healthcare
Year: 2007
Subjects: organiseeruv kopsupõletik, oblitereeruv bronhioliit, interstitsiaalne pneumoonia, kortikosteroidravi

description: Krüptogeenne organiseeruv pneumoonia (KOP) (ingl Cryptogenic Organizing Pneumonia, COP) on teadmata etioloogiaga mittespetsiifiliste üld- ja respiratoorsete haigussümptomitega nagu palaviku, köha,  nõrkuse ja progresseeruva düspnoega kulgev alaäge kopsuhaigus, mis klassifikatsiooni järgi kuulub idiopaatiliste interstitsiaalsete pneumooniate (IIP) hulka. Haigust defineeritakse patohistoloogilise leiu järgi, milleks on müofibrofblastidest koosnevate granulatsioon  koeliste struktuuride vohamine alveoolide, alveolaarjuhade ja respiratoorsete bronhioolide valendikku. KOPi-puhune sidekoe vohamine eristub selgesti IPFile iseloomulikust progresseeruvast pöördumatust fibroosist, kuna omab erakordset võimet reageerida glükokortikoid ravile. Ülevaateartiklis on lähemalt käsitletud KOPi patogeneesi, kliinilist pilti, diagnoosimist, avaldusvorme ja ravi ning toodud kahe haigusjuhu kirjeldused.


Eesti Arst 2007; 86 (2): 110–119
description: Eesti Arst, Veebruar 2007
Ionization and dissociation of molecules by electron impact
Creators: name: Yu, Mina Theresa Tung-Fai
Publisher: name: University of British Columbia
Year: 2011

description: A series of related alkyl and perfluoromethyl sulphides and disulphides has been studied by electron impact. The trend in the ionization potentials shows that when the bonding electrons are drawn further away from the sulphur atom(s), as in the case of the perfluoromethyl compounds, more energy is required to ionize the molecule. From the appearance potentials and subsidiary thermochemical data, the upper limits of all the heats of formation of the non-cyclic compounds were derived. The upper limits of the heats of formation of the principal fragment ions and radicals were also calculated. From the derived heats of formation, estimates of all the C-S and S-S bond strengths were made.
Encyclical letter paenitentiam agere. Pope John XXIII.
Creators: name: Catholic Church. Pope (1958-1963 : John XXIII).
Publisher: name: University of Notre Dame
Year: 2023

description:
 Cover title.
 Translation provided by the NCWC News Service.
 Paenitentiam agere. (1 July 1962) English.