cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Four RNA families with functional transient structures
Creators: name: Zhu, Jing Yun A
name: Meyer, Irmtraud M
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Evolutionary Biology
subject: Molecular Biology
subject: Genetics
subject: Medicine
subject: Biochemistry

description: Protein-coding and non-coding RNA transcripts perform a wide variety of cellular functions in diverse organisms. Several of their functional roles are expressed and modulated via RNA structure. A given transcript, however, can have more than a single functional RNA structure throughout its life, a fact which has been previously overlooked. Transient RNA structures, for example, are only present during specific time intervals and cellular conditions. We here introduce four RNA families with transient RNA structures that play distinct and diverse functional roles. Moreover, we show that these transient RNA structures are structurally well-defined and evolutionarily conserved. Since Rfam annotates one structure for each family, there is either no annotation for these transient structures or no such family. Thus, our alignments either significantly update and extend the existing Rfam families or introduce a new RNA family to Rfam. For each of the four RNA families, we compile a multiple-sequence alignment based on experimentally verified transient and dominant (dominant in terms of either the thermodynamic stability and/or attention received so far) RNA secondary structures using a combination of automated search via covariance model and manual curation. The first alignment is the Trp operon leader which regulates the operon transcription in response to tryptophan abundance through alternative structures. The second alignment is the HDV ribozyme which we extend to the 5′ flanking sequence. This flanking sequence is involved in the regulation of the transcript's self-cleavage activity. The third alignment is the 5′ UTR of the maturation protein from Levivirus which contains a transient structure that temporarily postpones the formation of the final inhibitory structure to allow translation of maturation protein. The fourth and last alignment is the SAM riboswitch which regulates the downstream gene expression by assuming alternative structures upon binding of SAM. All transient and dominant structures are mapped to our new alignments introduced here.
Toxicity screening to human peripheral blood mononuclear cells and Wistar rats by Crocodylus siamensisliver extracts
Creators: name: Thanannat Meemark
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Crocodylus siamensis
Liver
Immunomodulatory
Byproducts

description: Archives of Allied Health Sciences, 33, 2, 28-41
title: Eduquer à la citoyenneté au cycle I en améliorant la coopération en classe
title: Eduquer à la citoyenneté au cycle I en améliorant la coopération en classe
titleType: AlternativeTitle
Creators: name: Heuwekemeijer, Lucie
name: Zerika, Sarah
Publisher: name: Unknown
Year: 0
Subjects: subject: coopération
subject: ateliers philo
subject: conseil de classe
subject: jeux coopératifs
subject: éducation à la paix
subject: respect

description: Nous avons choisi de travailler sur la thématique de la coopération. Enseigner la citoyenneté au cycle I nous semblait essentiel pour le vivre-ensemble, et la coopération est un concept que nous recherchons à améliorer dans nos classes. Nous avons trouvé abondamment de théorie sur la philosophie en classe et la pédagogie coopérative, mais pas assez d’outils pratiques à notre goût. Durant notre processus de recherche, nous avons choisi de mettre en oeuvre des ateliers philo et des conseils de classe dans le but d’amener plus de coopération au sein de nos classes, en développant certaines capacités transversales présentes dans le PER. Nous présenterons et analyserons les résultats obtenus et nous finirons sur une ouverture avec quelques pistes pour le futur.
Reduction of need for repeat chest x-rays caused by insufficient inspiration through enhanced patient communication
Creators: name: Woranut Iampa
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Repeat/reject analysis
Chest x-ray examination
Inadequate/insufficient inspiration
Geriatric patients
Patient communication

description: Archives of Allied Health Sciences, 33, 2, 42-47
Factors associated with multidrug-resistant Pseudomonas aeruginosa infection: a hospital-based case-control study
Creators: name: Peechanika Chopjitt
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Multidrug resistance
Pseudomonas aeruginosa
Mechanical ventilator
Endotracheal tube

description: Archives of Allied Health Sciences, 33, 2, 48-55
Instability of Rotationally Tuned Dipolar Bose-Einstein Condensates
Creators: name: Prasad, S. B.
name: Bland, T.
name: Mulkerin, Brendan
name: Parker, N. G.
name: Martin, A. M.
Publisher: name: Swinburne
Year: 2024

description: The possibility of effectively inverting the sign of the dipole-dipole interaction, by fast rotation of the dipole polarization, is examined within a harmonically trapped dipolar Bose-Einstein condensate. Our analysis is based on the stationary states in the Thomas-Fermi limit, in the corotating frame, as well as direct numerical simulations in the Thomas-Fermi regime, explicitly accounting for the rotating polarization. The condensate is found to be inherently unstable due to the dynamical instability of collective modes. This ultimately prevents the realization of robust and long-lived rotationally tuned states. Our findings have major implications for experimentally accessing this regime.
The association of medial scapular muscle pain on distance of mouth opening in participants with scapulocostal syndrome: an exploratory study
Creators: name: Wilawan Kanhachon
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Myogenic-TMD
Upper quarter pain syndrome
Myofascial linkage
Chronic pain
Neck pain

description: Archives of Allied Health Sciences, 33, 2, 66-73
Effects of positive expiratory pressure and breath stacking training on pulmonary function in cardiac surgery patients: a randomized controlled trial
Creators: name: Porraporn Sriwannawit
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Positive expiratory pressure
Breath stacking
Chest physical therapy
Cardiac surgery
Pulmonary function

description: Archives of Allied Health Sciences, 33, 3, 16-28
title: Frank Scheffer
Publisher: name: EHESS
Year: 2016

description: Diplômé de l’Académie Hollandaise de Cinéma et de Télévision (1982), Frank Scheffer est un réalisateur et producteur de documentaires qui a consacré une partie importante de ses films aux musiques contemporaines et actuelles. Son œuvre se distingue tant par sa recherche formelle que par son amplitude, offrant un vaste panorama de la musique du 20ème siècle et de ses grandes figures : Karlheinz Stockhausen, John Cage, Elliott Carter, Steve Reich, Philip Glass, Pierre Boulez, mais aussi Frank Zappa et d’autres. Dès son premier film, Zoetrope People (1980), une rencontre avec Francis Ford Coppola, il s’intéresse aux relations entre sons, images et musiques. Il explore ensuite ces croisements selon différentes modalités, réalisant notamment le clip A Day pour le groupe XYMOX (1985). Avec Marina Abramovic, qui le présente à John Cage, il s’att
A combination of urinary neutrophil gelatinase-associated lipocalin and urine albumin creatinine ratio as potential biomarkers for the early diagnosis of CKD in type 2 diabetic patients
Creators: name: Rattana Pirom
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Neutrophil gelatinase-associated lipocalin
Diabetes
Diabetic nephropathy

description: Archives of Allied Health Sciences, 33, 3, 29-41
Predicting the Spatio-Temporal Evolution of Chronic Diseases in Population with Human Mobility Data.
Creators: name: Wang, Yingzi
name: Zhou, Xiao
name: Mascolo, C
name: Noulas, Anastasios
name: Xie, Xing
name: Liu, Qi
Publisher: name: IJCAI
Year: 2018
Subjects: 4605 Data Management and Data Science
46 Information and Computing Sciences
Generic health relevance
Metabolic and endocrine
3 Good Health and Well Being

description: Chronic diseases like cancer and diabetes are major threats to human life. Understanding the distribution and progression of chronic disease of a population is important in assisting the allocation of treatment services and resources as well as the design of policies in preemptive healthcare. Traditional methods to obtain large scale indicators on population health, e.g., surveys and statistical analysis, can be costly and time-consuming and often lead to a coarse spatio-temporal picture. In this paper, we leverage a dataset describing the human mobility patterns of citizens in a large metropolitan area. By viewing local human lifestyles we predict the evolution rate of several chronic diseases at the level of a city neighborhood. We apply the combination of a collaborative topic modeling (CTM) and a Gaussian mixture method (GMM) to tackle the data sparsity challenge and achieve robust predictions on health conditions simultaneously. Our method enables the analysis and prediction of disease rate evolution at fine spatio-temporal scales and demonstrates the potential of incorporating datasets from mobile web sources to improve population health monitoring. Evaluations using real-world check-in and chronic disease morbidity datasets in the city of London show that the proposed CTM+GMM
D4.1: Interoperable and Secure Flow of Information - Cyber-physical Sphere and Interoperability Aspects in the Utilities Regarding the DWC Solutions
Creators: name: Schwarzmüller, Hella
name: Vennesland, Audun
name: Haro, Peter Halland
name: Bour, Guillaume
Publisher: name: Zenodo
Year: 2021

description: D4.1 contains the documentation of the baseline situation in utilities regarding the implementation of sensors, models and systems in the frame of developing the DWC digital solutions. Structured fact sheets summarize a questionnaire sent to the utility partners and the technology providers to evaluate the existing framework, foreseen or used data architectures, and to provide the basis for the strategic and tactical risk analysis to be performed within T4.2 and for developing a semantic middleware within T4.3.
description: Version (v0.2.0) re-submitted to EC on 2021-03-10
Does the arm swing exercise benefit spatio-temporal parameters for female elderly?
Creators: name: Xiao, Zhen
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Shuai Shou Gong Training
Elderly Females
Stance Phase
Swing Phase
Stride Length

description: Archives of Allied Health Sciences, 33, 3, 42-53
Preparation of Thin Films for Elemental Analysis of Nail Polish by Wavelength Dispersive X-Ray Fluorescence Spectroscopy
Creators: name: McWilliams, Andrea C.
name: Martin, Al A.
name: Levine, Michael A.
name: Levine, Keith E.
name: Felder, Lauren
name: Young, Daniel J.
name: Harrington, James M.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cardiology
Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Molecular Biology
Cell Biology
Physics
Biochemistry
Biophysics

description: Determination of the elemental composition of cosmetic products for quality control and impurity analysis has traditionally been performed using plasma spectroscopic techniques that feature time-consuming, hazardous, and completely destructive sample preparation steps. Wavelength dispersive X-ray fluorescence spectroscopy (WDXRF) allows for quantitative and qualitative analysis of the elemental composition of materials for a range of elemental masses with less extensive sample preparation and higher sample throughput. WDXRF analysis requires that samples be of uniform thickness and prepared reproducibly. The analysis of products with a high organic solvent content, such as nail polish, by WDXRF has not previously been successful due to sample preparation reproducibility challenges. The goal of this investigation was to develop a method for reproducible preparation of nail polish using a thin film applicator. Samples were quantitatively analyzed for fluorine, sodium, magnesium, aluminum, silicon, phosphates, sulfates, chloride, potassium, calcium, titanium, vanadium, manganese, and iron to demonstrate the application of this sample preparation technique to a wide range of elemental masses. The developed preparation method was used to produce replicate thin films with a high degree of reproducibility. Further, the quantitative results obtained using WDXRF exhibit strong agreement with those obtained using inductively coupled plasma optical emission spectroscopy (ICP-OES), demonstrating consistency between independent analytical techniques.
Understanding Dyslexia Through Personalized Large-Scale Computational Models
Creators: name: Perry, Conrad
name: Zorzi, Marco
name: Ziegler, Johannes C.
Publisher: name: Swinburne
Year: 2024

description: Learning to read is foundational for literacy development, yet many children in primary school fail to become efficient readers despite normal intelligence and schooling. This condition, referred to as developmental dyslexia, has been hypothesized to occur because of deficits in vision, attention, auditory and temporal processes, and phonology and language. Here, we used a developmentally plausible computational model of reading acquisition to investigate how the core deficits of dyslexia determined individual learning outcomes for 622 children (388 with dyslexia). We found that individual learning trajectories could be simulated on the basis of three component skills related to orthography, phonology, and vocabulary. In contrast, single-deficit models captured the means but not the distribution of reading scores, and a model with noise added to all representations could not even capture the means. These results show that heterogeneity and individual differences in dyslexia profiles can be simulated only with a personalized computational model that allows for multiple deficits.
title: John-Paul Sniadecki
Publisher: name: EHESS
Year: 2016

description: Séance en partenariat avec le cycle « Paroles de créateurs » du Cerlom et avec le soutien de l’Ecole doctorale de l’Inalco  Ma rencontre avec John-Paul Sniadecki a eu lieu dans un village d’artistes situé non loin de Pékin en 2010. Il menait alors des enquêtes de terrain pour sa thèse de doctorat, et sillonnait la Chine en recherche de lieux où poser sa caméra. Ses documentaires rendent compte de son expérience chinoise en prêtant une attention égale aux dimensions animées et inanimées du monde. Ce faisant, sa caméra s’attarde sur les machines et les bâtiments qui habitent l’espace, tandis que les bruits ambiants sont mixés pour composer des morceaux de musique « concrète ». La musicalité du lieu accompagne ainsi la déambulation du cinéaste et renforce les sentiments ressentis dans les différents espaces traversés. Le spectateur est alors
Four RNA families with functional transient structures
Creators: name: Zhu, Jing Yun A
name: Meyer, Irmtraud M
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Evolutionary Biology
subject: Molecular Biology
subject: Genetics
subject: Medicine
subject: Biochemistry

description: Protein-coding and non-coding RNA transcripts perform a wide variety of cellular functions in diverse organisms. Several of their functional roles are expressed and modulated via RNA structure. A given transcript, however, can have more than a single functional RNA structure throughout its life, a fact which has been previously overlooked. Transient RNA structures, for example, are only present during specific time intervals and cellular conditions. We here introduce four RNA families with transient RNA structures that play distinct and diverse functional roles. Moreover, we show that these transient RNA structures are structurally well-defined and evolutionarily conserved. Since Rfam annotates one structure for each family, there is either no annotation for these transient structures or no such family. Thus, our alignments either significantly update and extend the existing Rfam families or introduce a new RNA family to Rfam. For each of the four RNA families, we compile a multiple-sequence alignment based on experimentally verified transient and dominant (dominant in terms of either the thermodynamic stability and/or attention received so far) RNA secondary structures using a combination of automated search via covariance model and manual curation. The first alignment is the Trp operon leader which regulates the operon transcription in response to tryptophan abundance through alternative structures. The second alignment is the HDV ribozyme which we extend to the 5' flanking sequence. This flanking sequence is involved in the regulation of the transcript's self-cleavage activity. The third alignment is the 5' UTR of the maturation protein from Levivirus which contains a transient structure that temporarily postpones the formation of the final inhibitory structure to allow translation of maturation protein. The fourth and last alignment is the SAM riboswitch which regulates the downstream gene expression by assuming alternative structures upon binding of SAM. All transient and dominant structures are mapped to our new alignments introduced here.
The geography of international conservation interest in South American deforestation frontiers
Creators: name: Qin, Siyu
name: Kuemmerle, Tobias
name: Meyfroidt, Patrick
name: Napolitano Ferreira, Mariana
name: Gavier-Pizarro, Gregorio
name: Periago, Maria Eugenia
name: Dos Reis, Tiago N.P.
name: Romero-Muñoz, Alfredo
name: Yanosky, Alberto
Publisher: name: Humboldt-Universität zu Berlin
Year: 2022
Subjects: subject: Amazon
subject: Atlantic forest
subject: biodiversity conservation
subject: Caatinga
subject: Cerrado
subject: foreign aid
subject: funding
subject: Gran Chaco
subject: Pantanal
subject: telecoupling
subject: 570 Biologie

description: International funding is increasingly important in supporting conservation in mega-biodiverse countries. However, it remains unclear which donors invest in which conservation objectives and where, making it difficult to identify gaps and key actors to influence. Here we identified 1947 foreign-aided conservation projects in South America's major deforestation frontiers and summarized their objectives and interventions over time and space. We found that conserving nature for its own sake and for ecosystem services remained key objectives, but the types of interventions varied considerably over time. Geographically, international conservation prioritized moist forests over drier biomes, despite equally high deforestation risk. Different donor groups emphasized specific objectives and interventions that reflected socioecological links (e.g., bird migration, colonial history) between donating and receiving regions, as well as the donors’ values (e.g., iconic/endangered species, human rights). These telecoupled patterns provide both opportunities and barriers for conservation and have implications for conservation prioritization strategies.
Loughborough University and figshare Case Study
Creators: name: Hyndman, Alan
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications
subject: Science Policy

description: Loughborough University are pioneering a research data management platform in partnership with figshare, Symplectic and Arkivum. This case study looks at the selection process of how and why Loughborough chose this solution.
Trace-level determination of pyrethroid, neonicotinoid and carboxamide pesticides in beeswax using dispersive solid-phase extraction followed by ultra-high-performance liquid chromatography-tandem mass spectrometry
Creators: name: Jabot, Claire
name: Maëva Fieu
name: Giroud, Barbara
name: Buleté, Audrey
name: Casabianca, Hervé
name: Vulliet, Emmanuelle
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Biochemistry

description: The aim of the work was to develop an analytical procedure able to quantify traces of 13 neonicotinoids and pyrethroids as well as carboxamide in beeswax at low levels (ng g−1) to evaluate the contamination. For this purpose, an efficient sample preparation procedure was developed based on solid–liquid extraction using dispersive diatomaceous earth and acetonitrile. This step was followed by a selective and sensitive analysis based on ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (ESI-MS/MS). This analytical procedure was validated based on International Conference on Harmonization guidelines. The limits of quantification ranged from 1 ng g−1 (thiamethoxam, clothianidin, imidacloprid, acetamiprid, thiacloprid and boscalid) to 40 ng g−1 (lambda-cyhalothrin). The method was then successfully applied to 60 samples of beeswax collected in several areas of France. The presence of thiacloprid, boscalid, imidacloprid and deltamethrin in beeswax was confirmed. The most frequently quantified pesticide was boscalid.
Recipes for inducing cold denaturation in an otherwise stable protein.
Creators: name: Bitonti, Angela
name: Puglisi, Rita
name: Meli, Massimiliano
name: Martin, Stephen R
name: Colombo, Giorgio
name: Temussi, Piero Andrea
name: Pastore, Annalisa
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: Chemical Biology & High Throughput
Structural Biology & Biophysics

description: Although cold denaturation is a fundamental phenomenon common to all proteins, it can only be observed in a handful of cases where it occurs at temperatures above the freezing point of water. Understanding the mechanisms that determine cold denaturation and the rules that permit its observation is an important challenge. A way to approach them is to be able to induce cold denaturation in an otherwise stable protein by means of mutations. Here, we studied CyaY, a relatively stable bacterial protein with no detectable cold denaturation and a high melting temperature of 54 °C. We have characterized for years the yeast orthologue of CyaY, Yfh1, a protein that undergoes cold and heat denaturation at 5 and 35 °C, respectively. We demonstrate that, by transferring to CyaY the lessons learnt from Yfh1, we can induce cold denaturation by introducing a restricted number of carefully designed mutations aimed at destabilizing the overall fold and inducing electrostatic frustration. We used molecular dynamics simulations to rationalize our findings and demonstrate the individual effects observed experimentally with the various mutants. Our results constitute the first example of rationally designed cold denaturation and demonstrate the importance of electrostatic frustration on the mechanism of cold denaturation.
Applying software performance engineering method to development of interactive software
Creators: name: Yang, Yun
name: Cheng, Jia Xing
Publisher: name: Swinburne
Year: 2024

description: Performance issues are vital to the success of many interactive software systems, including software development tools and Web-based tools. However, the issue of performance engineering is still not emphasized in the process of software development. The key aim of this paper is to illustrate an effective method to achieve satisfactory performance for interactive software after careful design. This paper presents how to apply the software performance engineering (SPE) method by focusing on performance estimation at the design stage, and its effect on determining implementation approaches, in the development of interactive software tools. In addition to the rigid quantitative estimation method originated from SPE, this paper argues that the performance can also be cost-effectively estimated either semi-quantitatively or non-quantitatively. With the experience results described in this paper, it is suggested that it may not be compulsory to achieve direct quantitative performance estimation from environment specifications for every software development as advocated by the SPE method. This paper demonstrates a combination of analytical and experimental approaches to assessing the performance at early stages in development of software tools.
Cytotoxity of two new coumarin derivatives isolated from Launaea mucronata
Creators: name: El-Sharkawy, Eman R.
name: Mahmoud, Khaled
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Cell Biology
subject: Engineering
subject: Biochemistry

description: The chloroform fraction of methanol (MeOH) extract of the aerial parts of Launaea mucronata was in vitro investigated for cytotoxicity against HCT116, HepG2 and MCF-7 cell lines, and resulted with IC50 = 20.0, 18.6 and 14.30 μg/mL, respectively. The chloroform fraction of the MeOH extract was subjected to further fractionation, which led to the isolation of two new coumarin compounds (6-isobutyl coumarin and 6-isobutyl-7-methyl- coumarin). The structures of the new compounds were elucidated by high field 1D and 2D NMR and ESI-MS spectroscopies. Low polar fractions revealed the isolation of other known triterpene compounds which were identified according to its spectral data and comparison with the literature. New coumarin compounds show high cytotoxicity against MCF-7, HCT116 and HepG2 cell lines.
Molecular fingerprint-based spiking neural network QSAR for bioconcentration prediction
Creators: name: Nascimben, Mauro
name: Spriano, Silvia
name: Venturin, Manolo
name: Rimondini, Lia
Publisher: name: Zenodo
Year: 2021

description: "Molecular fingerprint-based spiking neural network QSAR for bioconcentration prediction",
 Mathematical Modelling and Control for Healthcare and Biomedical Systems, MCHBS 2021 Virtual Workshop,
 Italian National Research Council, September 28-30, 2021, Poster Presentation
MPEC 2024-V17 : 2024 UU11
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 UU11

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Density-based clustering for data containing two types of points
Creators: name: Pei, Tao
name: Weiyi Wang
name: Hengcai Zhang
name: Ma, Ting
name: Yunyan Du
name: Chenghu Zhou
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Marine Biology
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: Cell Biology
subject: Microbiology
subject: Medicine
subject: Biophysics

description: When only one type of point is distributed in a region, clustered points can be seen as an anomaly. When two different types of points coexist in a region, they overlap at different places with various densities. In such cases, the meaning of a cluster of one type of point may be altered if points of the other type show different densities within the same cluster. If we consider the origins and destinations (OD) of taxicab trips, the clustering of both in the morning may indicate a transportation hub, whereas clustered origins and sparse destinations (a hot spot where taxis are in short supply) could suggest a densely populated residential area. This cannot be identified by previous clustering methods, so it is worthwhile studying a clustering method for two types of points. The concept of two-component clustering is first defined in this paper as a group containing two types of points, at least one of which exhibits clustering. We then propose a density-based method for identifying two-component clusters. The method is divided into four steps. The first estimates the clustering scale of the point data. The second transforms the point data into the 2D density domain, where the x and y axes represent the local density of each type of point around each point, respectively. The third determines the thresholds for extracting the clusters, and the fourth generates two-component clusters using a density-connectivity mechanism. The method is applied to taxicab trip data in Beijing. Three types of two-component clusters are identified: high-density origins and destinations, high-density origins and low-density destinations, and low-density origins and high-density destinations. The clustering results are verified by the spatial relationship between the cluster locations and their land-use types over different periods of the day.
Actin nanotracks for hybrid nanodevices based on linear protein molecular motors
Creators: name: Watson, G. S.
name: Cahill, C.
name: Blach, J.
name: Myhra, S.
name: Alexeeva, Y.
name: Ivanova, Elena
name: Nicolau, D. V.
Publisher: name: Swinburne
Year: 2024

description: Hybrid nano-devices based on linear protein molecular motors working on micro/nano-engineered surfaces that operate in a 'cargo architecture', i.e. motor functionalized nano-objects running on nano-tracks, offer more opportunities than the inverse 'sliding architecture' because it fully uses the information regarding directionality which is encoded in tracks, i.e. actin filaments or microtubules. However, this architecture requires the development of techniques for nanolithography with actin filaments (or microtubules) based on molecular self-assembly on engineered surfaces. The present contribution reports on the progress we have made regarding the building of actin nanostructures that would preserve the inherent information over extended micro-sized areas.
What data and analytics can and do say about effective learning
Creators: name: Lodge, Jason M.
name: Corrin, Linda
Publisher: name: Swinburne
Year: 2024

description: The collection and analysis of data about learning is a trend that is growing exponentially in all levels of education. Data science is poised to have a substantial influence on the understanding of learning in online and blended learning environments. The mass of data already being collected about student learning provides a source of greater insights into student learning that have not previously been available, and therefore is liable to have a substantial impact on and be impacted by the science of learning in the years ahead.
Generation of single photons and Schrödinger kitten states of light
Creators: name: Neergaard-Nielsen, Jonas
Publisher: name: figshare
Year: 2015
Subjects: Quantum Mechanics

description: PhD thesis, defended at the University of Copenhagen, Faculty of Science in September 2008. The thesis details our experimental efforts on generating highly non-classical states of a beam of light using the processes of down-conversion/quadrature squeezing and photon subtraction, as well as the complete characterization of these using homodyne tomographic measurements.
Commonwealth Blue Economy plans and policies and other institutional arrangements from Institutionalising the Blue Economy: an examination of variations and consistencies among Commonwealth countries
Creators: name: Voyer, Michelle
name: Benzaken, Dominique
name: Rambourg, Constance
Publisher: name: The Royal Society
Year: 2022
Subjects: Environmental Science

description: The Blue Economy is a catch all term that is used to describe a wide variety of development approaches and priorities in the ocean and coastal areas. A number of distinct, and sometimes conflicting discourses have emerged in relation to the Blue Economy, which are distinguished by the degree to which they prioritize different development objectives. This paper explores the range of Blue Economy interpretations, governance strategies and implementation approaches that exist across Commonwealth countries. Key Blue Economy policy statements and governance instruments are analysed in order to ascertain the way the Blue Economy is being institutionalized at a national level, with reference to the Sustainable Development Goals and the Commonwealth Blue Charter. High-level Blue Economy objectives appear to prioritize economic and environmental objectives, with limited engagement with equity objectives including food security and gender equality. Blue Economy objectives are primarily being institutionalized through a diverse array of strategies, plans and policies with limited information on mechanisms for implementation. Finally, there are signs that the Blue Economy may be facilitating a greater degree of integration across sectoral management, with the emergence of range of boundary-crossing arrangements in a number of the countries examined.This article is part of the theme issue ‘Nurturing resilient marine ecosystems’.
Migration pattern analysis of faculty members based on scientific disciplines: the case of the University of Tehran
Creators: name: Tavosi, Maryam
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460105
subject: Applications in social sciences and education

description: Choosing the right field of study is a crucial moment that can determine an academic's professional future. While it is typically recommended for those at the start of their scientific career to carefully select their field of study, studies in the field of field migration have shown that it often involves the transfer of knowledge and ideas between different fields. This research focuses on understanding the migration patterns of faculty members at the University of Tehran during the period from 1980 to 2022, specifically examining interdisciplinary shifts among academics. Data on faculty members’ academic backgrounds was collected, and 309 individuals with dual degrees were identified. VOS viewer and Node XL were used to illustrate their field mobility. With disciplines classified based on the International Standard Classification of Education (ISCED). The classification of disciplines was based on the International Standard Classification of Education (ISCED). The findings revealed that 74% of faculty members migrated to a completely different scientific field, while only 26% engaged in intra-field migrations. This indicates that most individuals crossed rigid boundaries between broad scientific fields rather than opting for neighboring fields within the same discipline. The study concludes that the pattern of field migrations highlights the artificiality of field borders and reflects researchers’ desire to foster communication and collaboration across various disciplines underscoring the importance of increased interdisciplinarity in scientific endeavors.
New salen-type manganese(III) Schiff base complexes derived from meso-1,2-diphenyl-1,2-ethylenediamine: In vitro anticancer activity, mechanism of action, and molecular docking studies
Creators: name: Damercheli, Maryam
name: Davood Dayyani
name: Behzad, Mahdi
name: Mehravi, Bita
name: Ardestani, Mehdi Shafiee
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Chemistry
Earth and Environmental Sciences
Cell Biology
Engineering
Biochemistry
Biophysics

description: Four new manganese(III) Schiff base complexes (1–4) were synthesized and characterized. The complexes have general formula [MnClLx] in which L represents a Schiff base ligand derived from condensation of meso-1,2-diphenyl-1,2-ethylenediamine with salicylaldehyde or its 3-OMe-, 5-Br-, or 5-OMe-derivatives (x = 1–4, respectively). The crystal structure of [MnClL1] (1) was characterized by X-ray crystallography. The in vitro anticancer activity of these complexes was evaluated by MTT and apoptosis assays against human breast (MCF-7) and liver (Hep G2) cancer cells. The complexes exhibited considerable antiproliferative activity against both cell lines (IC50 = 10.8–21.02 μM) comparable to cis-platin, except 4 (MCF-7). The highest activity was found for 1 with IC50 values of 13.62 μM (MCF-7) and 10.8 μM (Hep G2). Flow cytometry experiments showed that 1 induced apoptosis on MCF-7 tumor cell line. Docking simulations using AUTODOCK were also carried out. The results showed that all complexes fitted into the minor groove region of DNA.
title: Quantifying the impacts of the neonicotinoid restriction on oilseed rape pest control and productivity
Creators: name: Coston, Duncan James
Publisher: name: University of Reading
Year: 2023

description: Under current EU legislation the use of neonicotinoid seed treatments is banned in oilseed rape (OSR, Brassica napus L.) this has led to increased pest pressure and reduced cropping area of OSR in the UK. One main factor for increased pest pressure is from the cabbage stem flea beetle (Psylliodes chrysocephala) which also exhibits resistance to the only remaining alternative synthetic chemical control licensed in the UK. This thesis will in part examine the implications of the neonicotinoid restriction in pest control in the autumn from P.chrysocephala one of the primary target species for neonicotinoid seed treatments in OSR. Empirical field trials were performed to compare how alternative pest protection practices interact with pest control and crop yield. These were done alongside Neonicotinoid to gain a measure of the benefits of seed treatments. In control experiments undertaken during this thesis the interaction between P. chrysocephala and OSR are explored. Providing evidence that OSR can withstand higher pest pressure than current economic thresholds for insecticide application suggest. The relative effect of multiple pest protection methods were shown to be equal to crop protection and that neonicotinoid seed dressings did not show any observable benefit to OSR over un-treated seeds.
New salen-type manganese(III) Schiff base complexes derived from meso-1,2-diphenyl-1,2-ethylenediamine: In vitro anticancer activity, mechanism of action and molecular docking studies
Creators: name: Damercheli, Maryam
name: Davood Dayyani
name: Behzad, Mahdi
name: Mehravi, Bita
name: Ardestani, Mehdi Shafiee
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Chemistry
Earth and Environmental Sciences
Cell Biology
Engineering
Biochemistry
Biophysics

description: Four new manganese(III) Schiff base complexes (1-4) were synthesized and characterized. The complexes have general formula [MnClLx] in which L represents a Schiff base ligand derived from condensation of meso-1,2-diphenyl-1,2-ethylenediamine with salicylaldehyde or its 3-OMe-, 5-Br- or 5-OMe-derivatives (x = 1-4, respectively). The crystal structure of [MnClL1] (1) was characterized by X-ray crystallography. The in vitro anticancer activity of these complexes was evaluated by MTT and apoptosis assays against human breast (MCF-7) and liver (Hep G2) cancer cells. The complexes exhibited considerable antiproliferative activity against both cell lines (IC50 = 10.8-21.02 μM) comparable to cis-platin, except 4 (MCF-7). The highest activity was found for 1 with IC50 values of 13.62 μM (MCF-7) and 10.8 μM (Hep G2). Flow cytometry experiments showed that 1 induced apoptosis on MCF-7 tumor cell line. Docking simulations using AUTODOCK were also carried out. The results showed that all complexes fitted into the minor groove region of DNA.
Nutrition and Infant Feeding in the PMTCT Context in Rwanda
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: This is a report from PATH to the Elisabeth Glaser Pediatric AIDS Foundation in Rwanda from 2005. At this time Rwanda, with encouragement from Paul Farmer, was focused on avoidance of breastfeeding as the "correct" approach to avoiding postnatal transmission. This paper was part of a number of efforts made at about that time to promote what some years later became the WHO recommendation, exclusive breastfeeding, followed by continued breastfeeding for those who could not at that time provide safe and nutritious food for the infant.
The role of health services research in the implementation of breastfeeding as a family planning method
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: This paper, on pp 14-20 of this WHO report, was written and presented in 1986 before there was any widespread awareness of or agreement regarding the lactation amenorrhea method of family planning. It points out that for many women, modern methods are either not available, or forbidden by religion, or family members. Training them in the importance of exclusive breastfeeding could help substantially in spacing their babies.
Economic and social implications of breastfeeding
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: This paper, presented to a UNICEF meeting in Zimbabwe in January, 1983, calls for a "renewed commitment to equity in development and a healthy suspicion of "quick fix" approaches towards solving malnutrition problems. (Sadly, the trend today is instead strongly toward product-based approaches like ready to use supplemental foods.) It details possible causes and solutions of the bottle feeding problem, arguing that protection and support of breastfeeding must precede its promotion.
Letter to the editor, Acta Paediatrica
Creators: name: Greiner, Ted
name: Aarts, Clara
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: We point out that the abstract contradicts and fails to summarize a research article by Erlansson-Albertsson & Zetterström. The abstract hypothesizes that non-rule breastfeeding (often called “demand feeding”) favors the development of snacking throughout the day during childhood which in turn increases the risk for obesity. There is no support for this assertion, either in the article or elsewhere.
Determinants of the Breastfeeding Pattern Among Working Women in Sdo Paulo
Creators: name: Greiner, Ted
name: Rea, Marina Ferreira
name: Venancio, Sonia Isoyama
name: Batista, Luis Eduardo
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: In this 1999 study, the duration of exclusive breastfeeding was longer for women who had support for work and shorter for those who had to work weekends or did shift work.
Fortification of processed cereals should be mandatory
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: This commentary in the medical journal Lancet argues that food fortification can be an excellent public health tool for reducing major nutrient deficiencies but only if and when mandated. Otherwise, fortification serves mainly as a public relations approach for the food industry, potentially helping only those willing and able to pay more to get the same food.
The difficulty in coping with policy change for HIV and infant feeding counselors
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: WHO changed its global guidance related to HIV and infant feeding multiple times from 1997-2010. This paper describes the resulting challenges for counselors. Too little effort has been made to undo the harm done by outdated approaches recommended in the past.
AIUCD2019 - Book of Abstracts
Creators: name: Allegrezza, Stefano
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2019
Subjects: PE6_10 Web and information systems, database systems, information retrieval and digital libraries, data fusion
SH5 - Cultures and Cultural Production: Literature and philosophy, visual and performing arts, music, cultural and comparative studies

description: L’ottava edizione del Convegno nazionale dell’Associazione per l’Informatica Umanistica e la Cultura Digitale, collocandosi nel solco delle precedenti edizioni, si pone l’obiettivo di costituire un punto di incontro tra studiosi delle diverse discipline che - a vario titolo - fanno capo alle cosiddette Digital Humanities: umanisti digitali, informatici, linguisti, storici, archeologi, musicologi, filologici e non solo. Il tema principale di questa ottava edizione è la “Didattica e ricerca al tempo delle Digital Humanities”. Si tratta di un ambito vasto che accomuna pratiche e settori di studio interdisciplinari e multidisciplinari e che riguarda i mutamenti della didattica e della ricerca nell'era digitale.
Relationship of parental characteristics and feeding practices to overweight in infants and young children in Beijing, China
Creators: name: Greiner, Ted
name: Jingxiong, Jiang
name: Rosenqvist, Urban
name: Huishan, Wang
name: Koletzko, Bert
name: Guangli, Lian
name: Jing, Huang
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: Overweight parents with low education were more likely to have overweight children (under 3 years old) in Beijing study. Breastfeeding for at least 4 months was protective, especially when formula and solid foods were not given at the same time.
Effectiveness of URiSCAN 2 ACR strip test for albuminuria detection in screening of kidney disease
Creators: name: Laddawan Kateyam
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2020
Subjects: Albumin/creatinine
ratio (ACR)
Urine strip
Screening test

description: Archives of Allied Health Sciences, 32, 2, 1-7
Alteration of natural killer cell subset proportion is associated with risk factors of coronary artery disease in aging
Creators: name: Kanuengnit Srisak
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2020
Subjects: Immunosenescence
NK cell
Coronary artery disease
Chronic low-grade inflammation

description: Archives of Allied Health Sciences, 32, 2, 8-16
Optimization of vitamin C concentration to boost PMN function in healthy individuals
Creators: name: Laongthip Ruknarong
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Vitamin C
PMN function
Neutrophils
Phagocytosis
Oxidative burst

description: Archives of Allied Health Sciences, 33, 1, 1-8
Monitoring heart rate, heart rate variability, and subsequent performance in team-sport athletes receiving hypoxic or normoxic repeated sprint training
Creators: name: Hamlin, Michael J.
Publisher: name: Faculty of Associated Medical Sciences, Khon Kaen University, Thailand
Year: 2021
Subjects: Altitude
Rugby
YoYo-Intermittent recovery
Repeated sprint ability
Autonomic nervous system

description: Archives of Allied Health Sciences, 33, 1, 9-18
Beyond Melamine: More Reasons Not to Use Animal Milk in Infant Feeding
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: The Melamine scandal in China was the tip of an iceberg. It is always in the interests of dairy farmers and middle men to dilute milk. This increases revenues yet, below a liberal threshold, cannot be detected without the use of sophisticated methods. Melamine was added to milk in China as a way to by-pass one of these (measurement of nitrogen in milk). Dilution of animal milk is undoubtedly a routine event in most low-income countries, yet receives very little attention.