cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Chaotic strings in a near Penrose limit of AdS$_5\times T^{1,1}$
Creators: name: Asano, Yuhma
name: Kawai, Daisuke
name: Kyono, Hideki
name: Yoshida, Kentaroh
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We study chaotic motions of a classical string in a near Penrose limit of AdS$_5\times T^{1,1}$. It is known that chaotic solutions appear on $R\times T^{1,1}$, depending on initial conditions. It may be interesting to ask whether the chaos persists even in Penrose limits or not. In this paper, we show that sub-leading corrections in a Penrose limit provide an unstable separatrix, so that chaotic motions are generated as a consequence of collapsed Kolmogorov-Arnold-Moser (KAM) tori. Our analysis is based on deriving a reduced system composed of two degrees of freedom by supposing a winding string ansatz. Then, we provide support for the existence of chaos by computing Poincare sections. In comparison to the AdS$_5\times T^{1,1}$ case, we argue that no chaos lives in a near Penrose limit of AdS$_5\times$S$^5$, as expected from the classical integrability of the parent system.
description: 19 pages, 9 figures, LaTeX, v2: typos corrected and some clarifications added
(1900) James McGregor
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Identification of a Drosophila Vitamin K-dependent γ-Glutamyl Carboxylase
Creators: name: Stafford, Darrel W.
name: Li, Tao
name: Yang, Chao Tsung
name: Jin, Dayun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Using reduced vitamin K, oxygen, and carbon dioxide, gamma-glutamyl carboxylase post-translationally modifies certain glutamates by adding carbon dioxide to the gamma position of those amino acids. In vertebrates, the modification of glutamate residues of target proteins is facilitated by an interaction between a propeptide present on target proteins and the gamma-glutamyl carboxylase. Previously, the gastropod Conus was the only known invertebrate with a demonstrated vitamin K-dependent carboxylase. We report here the discovery of a gamma-glutamyl carboxylase in Drosophila. This Drosophila enzyme is remarkably similar in amino acid sequence to the known mammalian carboxylases; it has 33% sequence identity and 45% sequence similarity to human gamma-glutamyl carboxylase. The Drosophila carboxylase is vitamin K-dependent, and it has a K(m) toward a model pentapeptide substrate, FLEEL, of about 4 mm. However, unlike the human gamma-glutamyl carboxylase, it is not stimulated by human blood coagulation factor IX propeptides. We found the mRNA for Drosophila gamma-glutamyl carboxylase in virtually every embryonic and adult stage that we investigated, with the highest concentration evident in the adult head.
Digital Learning and the Humanities
Creators: name: Küchler, Uwe
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2020

description: The current research and funding situation with regards to digital teaching and learning will be a starting point to further inquire about the mission, intent and self-styling of the humanities and the field of English. The proliferation of digital opportunities makes knowledge globally available and universally transferable in a technological sense. Yet, what about the changes that digitalization triggers in epistemology or cultural techniques of information management? And, what are the stakes of the humanities and their way of making meaning and creation of knowledge? Can the knowledge of the humanities or the field of English – here particularly language, narrative literature and culture – be communicated, taught or learned with digital means? The humanities make it their designated task to provide orientation and evaluation for the increasingly complex and fast-paced global developments and their diverse cultural, societal and educative contexts. It should be in the interest of the humanities and its disciplines, to find answers to the questions of benefits that can be provided by digitalization of educational fields. Puentedura's SAMR matrix (substitution, amplification, modification, redefinition) will be introduced to allow for an evaluation of digitalization processes and tools.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Vol 2 No 4 (2020): Standards – Margins – New Horizons. Teaching Language and Literature in the 21st Century
Interaction of Mammalian Mitochondrial Ribosomes with the Inner Membrane
Creators: name: Liu, Meiqin
name: Spremulli, Linda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: All of the products of mitochondrial protein biosynthesis in animals are hydrophobic proteins that are localized in the inner membrane. Hence, it is possible that the synthesis of these proteins could occur on ribosomes associated with the inner membrane. To examine this possibility, inner membrane and matrix fractions of bovine mitochondria were examined for the presence of ribosomes using probes for the rRNAs. Between 40 and 50% of the ribosomes were found to fractionate with the inner membrane. About half of the ribosomes associated with the inner membrane could be released by high salt treatment, indicating that they interact with the membrane largely through electrostatic forces. No release of the ribosome was observed upon treatment with puromycin, suggesting that the association observed is not due to insertion of a nascent polypeptide chain into the membrane. A fraction of the ribosomes remained with residual portions of the membranes that cannot be solubilized in the presence of Triton X-100. These ribosomes may be associated with large oligomeric complexes in the membrane.
Supplemental legends and tables from Mad1 influences interphase nucleoplasm organization and chromatin regulation in Drosophila
Creators: name: Raich, Natacha
name: Souhir Mahmoudi
name: Emre, Doruk
name: Karess, Roger E.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences

description: Additional controls and data corresponding to Figs 1-4.
(1902) Squire Hoyle
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supersymmetric gauged Double Field Theory: Systematic derivation by virtue of \textit{Twist}
Creators: name: Cho, Wonyoung
name: Fernández-Melgarejo, J. J.
name: Jeon, Imtak
name: Park, Jeong-Hyuck
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In a completely systematic and geometric way, we derive maximal and half-maximal supersymmetric gauged double field theories in lower than ten dimensions. To this end, we apply a simple twisting ansatz to the $D=10$ ungauged maximal and half-maximal supersymmetric double field theories constructed previously within the so-called semi-covariant formalism. The twisting ansatz may not satisfy the section condition. Nonetheless, all the features of the semi-covariant formalism, including its complete covariantizability, are still valid after the twist under alternative consistency conditions. The twist allows gaugings as supersymmetry preserving deformations of the $D=10$ untwisted theories after Scherk-Schwarz-type dimensional reductions. The maximal supersymmetric twist requires an extra condition to ensure both the Ramond-Ramond gauge symmetry and the $32$ supersymmetries unbroken.
description: 1+58 pages, section 4 enhanced, refs added. To appear in JHEP
Investigating H$α$, UV, and IR star-formation rate diagnostics for a large sample of z ~ 2 galaxies
Creators: name: Shivaei, Irene
name: Reddy, Naveen A.
name: Steidel, Charles C.
name: Shapley, Alice E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We use a sample of 262 spectroscopically confirmed star-forming galaxies at redshifts $2.08\leq z\leq 2.51$ to compare H$α$, UV, and IR star-formation-rate diagnostics and to investigate the dust properties of the galaxies. At these redshifts, the H$α$ line shifts to the $K_{s}$-band. By comparing $K_{s}$-band photometry to underlying stellar population model fits to other UV, optical, and near-infrared data, we infer the H$α$ flux for each galaxy. We obtain the best agreement between H$α$- and UV-based SFRs if we assume that the ionized gas and stellar continuum are reddened by the same value and that the Calzetti attenuation curve is applied to both. Aided with MIPS 24$μ$m data, we find that an attenuation curve steeper than the Calzetti curve is needed to reproduce the observed IR/UV ratios of galaxies younger than 100 Myr. Furthermore, using the bolometric star-formation rate inferred from the UV and mid-IR data (SFR$_{IR}$+SFR$_{UV}$), we calculated the conversion between the H$α$ luminosity and SFR to be $(7.5\pm1.3) \times 10^{-42}$ for a Salpeter IMF, which is consistent with the Kennicutt (1998) conversion. The derived conversion factor is independent of any assumption of the dust correction and is robust to stellar population model uncertainties.
description: Accepted for publication in ApJ, 11 pages, 6 figures, 2 tables
(1895) Mary Ann Pickard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Table S1; Tables S2 - S5; Figures S1 and S2 from Urban rats have less variable, higher protein diets.
Creators: name: E. Guiry
name: M. Buckley
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Over the past 1000 years, rats (Rattus spp.) have become one of the most successful and prolific pests in human society. Despite their cosmopolitan distribution across six continents and ubiquity throughout the world's cities, rat urban ecology remains poorly understood. We investigate the role of human foods in brown rat (Rattus norvegicus) diets in urban and rural areas over a 100 year period (ca AD 1790–1890) in Toronto, Canada using stable carbon (δ13C) and nitrogen (δ15N) isotope analyses of archaeological remains. We found that rat diets from urban sites were of higher quality and were more homogeneous and stable over time. By contrast, in rural areas, they show a wide range of dietary niche specializations that directly overlap, and probably competed, with native omnivorous and herbivorous species. These results demonstrate a link between rodent diets and human population density, providing, to our knowledge, the first long-term dietary perspective on the relative value of different types of human settlements as rodent habitat. This study highlights the potential of using the historical and archaeological record to provide a retrospective on the urban ecology of commensal and synanthropic animals that could be useful for improving animal management and conservation strategies in urban areas.
Digitale Fremdsprachenkompetenzen?
Creators: name: Burger, Claudia
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2020

description: In diesem Beitrag werden infolge der Veröffentlichung des Strategiepapiers „Bildung in der digitalen Welt“ der Kultusministerkonferenz Überlegungen zur fachspezifischen Ausgestaltung des dort vorgeschlagenen Rahmenmodells zu den „Kompetenzen in der digitalen Welt“ in Bezug auf das Fach Englisch angestellt. Hierbei handelt es sich um Vorüberlegungen für das Projekt „Digi_Gap – Digitale Lücken in der Lehrkräftebildung schließen“, welches von 2020 bis 2023 als Teil der Qualitätsoffensive Lehrerbildung vom Bundesministerium für Bildung und Forschung (BMBF) an der Goethe-Universität Frankfurt am Main gefördert wird und in dessen Rahmen eine Modellierung digitaler Fremdsprachenkompetenzen Englisch erfolgen soll. Neben den Empfehlungen der Kultusministerkonferenz werden weitere Kompetenzmodelle sowie Ansätze und Konzepte aus dem Bereich der (Fremd-)Sprachenforschung herangezogen, um vorläufige Rückschlüsse bezüglich der avisierten Modellierung zu ziehen, die mit der Perspektive schulischer Bildung im post-digitalen Zeitalter erarbeitet werden soll.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Vol 2 No 4 (2020): Standards – Margins – New Horizons. Teaching Language and Literature in the 21st Century
Supplemental Figures from Mad1 influences interphase nucleoplasm organization and chromatin regulation in Drosophila
Creators: name: Raich, Natacha
name: Souhir Mahmoudi
name: Emre, Doruk
name: Karess, Roger E.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences

description: Figs 1-4.
Fakt oder Fiktion? Die historischen Merkmale der Hexenverfolgung im Spiegel von Daniel Kehlmanns Tyll
Creators: name: Anders, Sabine
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: Geschichtsdarstellung; Historizität; Hexenbild; Hexenprozess
subject: 830 Deutsche Literatur

description: In Daniel Kehlmanns Roman Tyll wird der Müller Claus, Vater der Titelfigur, der Hexerei verdächtigt, angeklagt, für schuldig befunden und hingerichtet. Im Rahmen dieser Arbeit wird analysiert, inwiefern sich das fiktionale Prozessgeschehen mit der historischen Realität vergleichen lässt und welche frühneuzeitlichen Vorstellungen von Hexerei dem Roman zugrunde liegen. Insbesondere steht, neben dem im Roman realistisch geschilderten Prozessgeschehen, die Ähnlichkeit zwischen dem Müller Claus und Menocchio, einem historisch belegten italienischen Müller, im Fokus, dessen Prozessakten von Carlo Ginzburg analysiert und veröffentlicht wurden. Zudem wird auf die Elemente des frühneuzeitlichen kumulativen Hexenbildes eingegangen, die sich an zahlreichen Stellen im Roman wiederfinden. Die facettenreiche Darstellung der Hexenverfolgung im Allgemeinen, die beispielhafte Darstellung des Hexenprozesses sowie der mentalitätsgeschichtliche Bezug lassen auf eine ausgiebige Recherchetätigkeit Daniel Kehlmanns schließen. Durch die Kombination von sozial-, politik- mentalitäts- und klimageschichtlichen Erkenntnissen mit übernatürlichen Elementen erschafft der Autor eine Welt, in der Fakt und Fiktion verschwimmen.
MEK Inhibition Enhances Paclitaxel-induced Tumor Apoptosis
Creators: name: MacKeigan, Jeffrey P.
name: Collins, Timothy S.
name: Ting, Jenny P.Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: The anti-cancer drug paclitaxel (Taxol) alters microtubule assembly and activates pro-apoptotic signaling pathways. Previously, we and others found that paclitaxel activates endogenous JNK in tumor cells, and the activation of JNK contributes to tumor cell apoptosis. Here we find that paclitaxel activates the prosurvival MEK/ERK pathway, which conversely may compromise the efficacy of paclitaxel. Hence, a combination treatment of paclitaxel and MEK inhibitors was pursued to determine whether this treatment could lead to enhanced apoptosis. The inhibition of MEK/ERK with a pharmacologic inhibitor, U0126, together with paclitaxel resulted in a dramatic enhancement of apoptosis that is four times more than the additive value of the two drugs alone. Enhanced apoptosis was verified by the terminal transferase-mediated dUTP nick end labeling assay, by an enzyme-linked immunosorbent assay for histone-associated DNA fragments, and by flow cytometric analysis for DNA content. Specificity of the pharmacologic inhibitor was confirmed by the use of (a) a second MEK/ERK inhibitor and (b) a transdominant-negative MEK. Enhanced apoptosis was verified in breast, ovarian, and lung tumor cell lines, suggesting this effect is not cell type-specific. This is the first report of enhanced apoptosis detected in the presence of paclitaxel and MEK inhibition and suggests a new anticancer strategy.
Modelling of the auto-ignition of hotspots in hydrogen air mixtures
Creators: name: Ezekwesili, Roseline
name: BELLENOUE, Marc
name: Strozzi, Camille
name: Bohon, Myles
Publisher: name: Zenodo
Year: 2023
Subjects: Hotspot
autoignition

description: In the context of pressure gain combustion, areas of increased reactivity called hotspots may arise in a chamber of premixed fuel and oxidizer. Auto-ignition of these hotspots leads to different combustion propagation modes including detonations. Detonations should be suppressed in constant volume combustors (CVC) and shockless explosion combustors (SEC) but promoted in detonation engines. Controlling the transitions between hotspot regimes is one of the keys to developing pressure gain combustion and wider combustion applications. Hydrogen is an attractive fuel for the future of aviation and therefore it is important that its combustion characteristics are understood and mastered. This paper aims to model the auto-ignition of hydrogen hotspots and the resulting combustion modes using the INSFLA code provided by the Karlsruhe Institute of Technology. The INSFLA code simulates 1-dimensional reacting flows for multi-step chemistry and multi-species transport models, uses full compressible Navier-Stokes equations and performs spatial discretization using the finite difference method. The code will be adapted to model hotspots in the context of autoignition. The model adopted for the hotspot is one where a linear temperature gradient is assumed within the hotspot radius and an auto-ignition wave propagates due to autoignition along this temperature gradient as shown in figure 1. Integral in building this mathematical model is selecting the appropriate reaction mechanism, running 0-dimensional simulations to determine the autoignition wave speed and heat release characteristics. Moreover, planar and spherical configurations will be tested to observe the effects geometry has on detonation development behavior. Experimental work exploring the effects of hydrogen on autoignition behavior will be completed using the experimental set-up shown in figure 2. The results from the numerical model will be compared to the experimental results to assess to what extent the model represents the structure of hotspots, the mechanism of the autoignition wave propagation, the interaction of the autoignition wave with the acoustic wave and the effects that hydrogen has on the detonation development behavior
Molecular Cloning and Characterization of a Human Mitochondrial Ceramidase
Creators: name: Lemasters, John J.
name: Qian, Ting
name: Hannun, Yusuf A.
name: Bielawska, Alicja
name: Roddy, Patrick
name: El Bawab, Samer
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: We have recently purified a rat brain membrane-bound nonlysosomal ceramidase (El Bawab, S., Bielawska, A., and Y. A. Hannun (1999) J. Biol. Chem. 274, 27948-27955). Using peptide sequences obtained from the purified rat brain enzyme, we report here the cloning of the human isoform. The deduced amino acid sequence of the protein did not show any similarity with proteins of known function but was homologous to three putative proteins from Arabidospis thaliana, Mycobacterium tuberculosis, and Dictyostelium discoideum. Several blocks of amino acids were highly conserved in all of these proteins. Analysis of the protein sequence revealed the presence at the N terminus of a signal peptide followed by a putative myristoylation site and a putative mitochondrial targeting sequence. The predicted molecular mass was 84 kDa, and the isoelectric point was 6.69, in agreement with rat brain purified enzyme. Northern blot analysis of multiple human tissues showed the presence of a major band corresponding to a size of 3.5 kilobase. Analysis of this major band on the blot indicated that the enzyme is ubiquitously expressed with higher levels in kidney, skeletal muscle, and heart. The enzyme was then overexpressed in HEK 293 and MCF7 cells using the pcDNA3. 1/His-ceramidase construct, and ceramidase activity (at pH 9.5) increased by 50- and 12-fold, respectively. Next, the enzyme was characterized using lysate of overexpressing cells. The results confirmed that the enzyme catalyzes the hydrolysis of ceramide in the neutral alkaline range and is independent of cations. Finally, a green fluorescent protein-ceramidase fusion protein was constructed to investigate the localization of this enzyme. The results showed that the green fluorescent protein-ceramidase fusion protein presented a mitochondrial localization pattern and colocalized with mitochondrial specific probes. These results demonstrate that this novel ceramidase is a mitochondrial enzyme, and they suggest the existence of a topologically restricted pathways of sphingolipid metabolism.
Wearing_procb_ESM from Evolved reductions in body temperature and the metabolic costs of thermoregulation in deer mice native to high altitude
Creators: name: Wearing, Oliver H.
name: Scott, Graham R.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: Supplementary Methods, Figures and Tables
Permeabilization via the P2X 7 Purinoreceptor Reveals the Presence of a Ca 2+ -activated Cl − Conductance in the Apical Membrane of Murine Tracheal Epithelial Cells
Creators: name: Thomas, Emma J.
name: Martsen, Elena
name: Gabriel, Sherif E.
name: Makhlina, Mariya
name: Boucher, Richard C.
name: Lethem, Mike I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Calcium-activated Cl(-) secretion is an important modulator of regulated ion transport in murine airway epithelium and is mediated by an unidentified Ca(2+)-stimulated Cl(-) channel. We have transfected immortalized murine tracheal epithelial cells with the cDNA encoding the permeabilizing P2X(7) purinoreceptor (P2X(7)-R) to selectively permeabilize the basolateral membrane and thereby isolate the apical membrane Ca(2+)-activated Cl(-) current. In P2X(7)-R-permeabilized cells, we have demonstrated that UTP stimulates a Cl(-) current across the apical membrane of CF and normal murine tracheal epithelial cells. The magnitude of the UTP-stimulated current was significantly greater in CF than in normal cells. Ion substitution studies demonstrated that the current exhibited a permselectivity sequence of Cl(-) > I(-) > Br(-) > gluconate(-). We have also determined a rank order of potency for putative Cl(-) channel blockers: niflumic acid > or = 5-nitro-2-(3-phenylpropylamino)benzoic acid > 4, 4'-diisothiocyanostilbene-2,2'-disulfonate > glybenclamide >> diphenlyamine-2-carboxylate, tamoxifen, and p-tetra-sulfonato-tetra-methoxy-calix[4]arene. Complete characterization of this current and the corresponding single channel properties could lead to the development of a new therapy to correct the defective airway surface liquid in cystic fibrosis patients.
Electronic Supplementary Material from In that vein: inflated wing veins contribute to butterfly hearing.
Creators: name: Penghui Sun
name: Mhatre, Natasha
name: Mason, Andrew
name: Yack, Jayne
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Neuroscience
subject: 110601 Biomechanics
subject: FOS: Health sciences
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Supplementary Methods and Results are provided in this file. This file includes four figures and two tables that are referred to in the main body of the text.
A Perceptual Measure for Evaluating the Resynthesis of Automatic Music Transcriptions
Creators: name: Simonetta, Federico
name: Avanzini, Federico
name: Ntalampiras, Stavros
Publisher: name: arXiv
Year: 2022
Subjects: subject: Sound (cs.SD)
subject: Machine Learning (cs.LG)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This study focuses on the perception of music performances when contextual factors, such as room acoustics and instrument, change. We propose to distinguish the concept of "performance" from the one of "interpretation", which expresses the "artistic intention". Towards assessing this distinction, we carried out an experimental evaluation where 91 subjects were invited to listen to various audio recordings created by resynthesizing MIDI data obtained through Automatic Music Transcription (AMT) systems and a sensorized acoustic piano. During the resynthesis, we simulated different contexts and asked listeners to evaluate how much the interpretation changes when the context changes. Results show that: (1) MIDI format alone is not able to completely grasp the artistic intention of a music performance; (2) usual objective evaluation measures based on MIDI data present low correlations with the average subjective evaluation. To bridge this gap, we propose a novel measure which is meaningfully correlated with the outcome of the tests. In addition, we investigate multimodal machine learning by providing a new score-informed AMT method and propose an approximation algorithm for the $p$-dispersion problem.
description: Accepted by Multimedia Tools and Applications (2022); supplementary materials are in the latex sources
Table S1 from Urban rats have less variable, higher protein diets
Creators: name: E. Guiry
name: M. Buckley
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Over the past 1000 years, rats (Rattus spp.) have become one of the most successful and prolific pests in human society. Despite their cosmopolitan distribution across six continents and ubiquity throughout the world's cities, rat urban ecology remains poorly understood. We investigate the role of human foods in brown rat (Rattus norvegicus) diets in urban and rural areas over a 100 year period (ca AD 1790–1890) in Toronto, Canada using stable carbon (δ13C) and nitrogen (δ15N) isotope analyses of archaeological remains. We found that rat diets from urban sites were of higher quality and were more homogeneous and stable over time. By contrast, in rural areas, they show a wide range of dietary niche specializations that directly overlap, and likely competed, with native omnivorous and herbivorous species. These results demonstrate a link between rodent diets and human population density, providing the first long-term dietary perspective on the relative value of different types of human settlements as rodent habitat. This study highlights the potential of using the historical and archaeological record to provide a retrospective on the urban ecology of commensal and synanthropic animals that could be useful for improving animal management and conservation strategies in urban areas.
That Accursed Island. Treasure Island and Imperial Disappointments
Creators: name: Loos, Theodora T.
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: Postcolonialism; Imperial Romance; Adventure Literature
subject: 420 Englisch
subject: 820 Englische Literatur

description: This essay examines the depictions of colonial spaces and the failure of imperial endeavours in Robert Louis Stevenson’s 1883 novel Treasure Island. By combining several theoretical approaches, the aim is to foreground the ways in which Stevenson subverts the norms of imperial romance and creates an adventure story that calls into question the very premise of its genre.
Sprachwandel und Textvielfalt sichtbar machen
Creators: name: Funke, Dorit
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2020

description: Texte in Lateinbüchern sind künstlich und didaktisiert. Die Sprache dieser Texte ist homogen und sieht immer gleich aus. Die Schüler*innen bekommen so den Eindruck, dass die lateinische Sprache sich nie verändert hat. Auch die Texte in der Übergangslektüre sowie in der Lektürephase sind insofern homogen, als dass sie zum Teil bearbeitet sind, zum Teil aus zeitlich ähnlichen Epochen stammen und für die Elite geschrieben wurden. Im Schriftbild unterscheiden sie sich gar nicht von den Lehrbuchtexten. Im Beitrag werden lateinische Schriftzeugnisse vorgestellt, die aus mehreren Jahrhunderten und von Verfassern aus unterschiedlichen Schichten stammen. Den Schüler*innen soll durch die Auseinandersetzung mit diesen Zeugnissenewusst gemacht werden, dass Latein eine „wirkliche“ Sprache war, die einem stetigen Wandel ausgesetzt war, wie es moderne Sprachen auch heute noch sind. Weiterhin soll gezeigt werden, dass Latein von Menschen aller sozialen Schichten benutzt wurde, was sich natürlich – wie heute – in Ausdruck und Stil niederschlägt. Schließlich soll aufgezeigt werden, dass Latein das verbindende Element nicht nur zwischen Nicht-Muttersprachler*innen und Muttersprachler*innen war, sondern auch zwischen Nicht-Muttersprachler*innen.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Vol 2 No 4 (2020): Standards – Margins – New Horizons. Teaching Language and Literature in the 21st Century
(1897) John Pickard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Global Englishes in the Classroom
Creators: name: Schildhauer, Peter
name: Schulte, Marion
name: Zehne, Carolin
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2020

description: Today’s learners of English will face the challenge of having to communicate with speakers of English from a variety of backgrounds in their future. The smallest fraction of their prospective interlocutors will be native speakers of well-known standard varieties such as British and American English. Researchers of different research paradigms have discussed the pedagogical implications of this diverse sociolinguistic reality, which we refer to by the term Global Englishes. The two strategies that are proposed frequently are a) to allow learners of English to encounter a variety of different Englishes in order to develop (listening) comprehension skills and b) to address pragmatic and interaction strategies that allow to deal with intercultural encounters and – in particular – communication barriers. Starting from this theoretical background, we first investigate one coursebook each for the intermediate and the advanced secondary school level in the German state North Rhine-Westphalia to find out to what extent current coursebooks provide Global Englishes material. We identify a trend to providing a considerable amount of material. However, even most recent ebooks rely on audio files despite the fact that they could include a higher amount of audio-visual material. We argue that in particular audio-visual material is well-suited for making students encounter Global Englishes in the classroom and move on to suggest TED-talks, advertisements and cinematic films as highly suitable sources of material. We illustrate our argument with examples and selected tasks for each category. We end the article by proposing specific activities that can be used to practice interaction strategies.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Vol 2 No 4 (2020): Standards – Margins – New Horizons. Teaching Language and Literature in the 21st Century
Overlaid wireless real-time communication hive : OVERWATCH
Creators: name: Loehrlein, Ryan
name: Spiller, Kendall
name: Snyder, Zackrey
Publisher: name: Unknown
Year: 2019

description: The Overlaid Wireless Real-Time Communication Hive (Overwatch) project is a design project
conducted in collaboration between the Mechanical Engineering and Computer Science departments at
the University of Southern Indiana. This project consisted of designing, building and testing a drone
swarm with the goal of creating a wireless real-time control system optimized for autonomous
platforms. More specifically, the drones were designed to communicate with each other in designated
teams to complete a task. The team completed, tested, programmed, and built three subsystems.
Consisting of the Ground Control Station (GCS) or the central communication hub, the small Unmanned
Aerial Systems (sUAS) or drones, and Swarm Intelligence (SI) or control algorithms. Through this project,
the Overwatch team was able to develop a complete GCS, an operational sUAS platform, and a fully
functioning SI algorithms. Through initial testing, the GCS has shown that it capable of controlling,
monitoring and operating the sUAS during flight operations while running the Swarm Intelligence.
Future testing will be executed to validate all functionality of the Overwatch project. This senior design
project allowed our team to overcome real world obstacles and complex technical issues while
successfully completing our main goal of creating a wireless real-time control system optimized for
autonomous platforms.
Current-Driven Dynamics of Skyrmions Stabilized in MnSi Nanowires Revealed by Topological Hall Effect
Creators: name: Liang, Dong
name: DeGrave, John P.
name: Stolt, Matthew J.
name: Tokura, Yoshinori
name: Jin, Song
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Skyrmions, novel topologically stable spin vortices, hold promise for next-generation magnetic storage due to their nanoscale domains to enable high information storage density and their low threshold for current-driven motion to enable ultralow energy consumption. One-dimensional (1D) nanowires are ideal hosts for skyrmions since they not only serve as a natural platform for magnetic racetrack memory devices but also can potentially stabilize skyrmions. Here we use the topological Hall effect (THE) to study the phase stability and current-driven dynamics of the skyrmions in MnSi nanowires. The THE was observed in an extended magnetic field-temperature window (15 to 30 K), suggesting stabilization of skyrmion phase in nanowires compared with the bulk (27 to 29.5 K). Furthermore, for the first time, we study skyrmion dynamics in this extended skyrmion phase region and found that under the high current-density of $10^{8}-10^{9} Am^{-2}$ enabled by nanowire geometry, the THE decreases with increasing current densities, which demonstrates the current-driven motion of skyrmions generating the emergent electric field. These results open up the exploration of nanowires as an attractive platform for investigating skyrmion physics in 1D systems and exploiting skyrmions in magnetic storage concepts.
Phosphorylation of Serine 43 Is Not Required for Inhibition of c-Raf Kinase by the cAMP-dependent Protein Kinase
Creators: name: He, Yaqin
name: Kozlowski, Piotr
name: Lee, Jung Weon
name: Graves, Lee M.
name: Sidovar, Matthew F.
name: Collins, Matthew A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: The activity of the serine/threonine kinase c-Raf (Raf) is inhibited by increased intracellular cAMP. This is believed to require phosphorylation with the cAMP-dependent protein kinase (PKA), although the mechanism by which PKA inhibits Raf is controversial. We investigated the requirement for PKA phosphorylation using Raf mutants expressed in HEK293 or NIH 3T3 cells. Phosphopeptide mapping of (32)P-labeled Raf (WT) or a mutant lacking a putative PKA phosphorylation site (serine to alanine, S43A) confirmed that serine 43 (Ser(43)) was the major cAMP (forskolin)-stimulated phosphorylation site in vivo. Interestingly, the EGF-stimulated Raf kinase activity of the S43A mutant was inhibited by forskolin equivalently to that of the WT Raf. Forskolin also inhibited the activation of an N-terminal deletion mutant Delta5-50 Raf completely lacking this phosphorylation site. Although WT Raf was phosphorylated by PKA, phosphorylation did not inhibit Raf catalytic activity in vitro, nor did forskolin treatment inhibit the activity of an N-terminally truncated Raf protein (Raf 22W) or a full-length Raf protein (Raf-CAAX) expressed in NIH 3T3 cells. In contrast, forskolin inhibited the EGF-dependent activation of a Raf isoform (B-Raf), lacking an analogous phosphorylation site to Ser(43). Thus, these results demonstrate that PKA exerts its inhibitory effects independently of direct Raf phosphorylation and suggests instead that PKA prevents an event required for the EGF-dependent activation of Raf.
A Dedicated English Portfolio for a Bilingual Primary School
Creators: name: Skorge, Patricia
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2020

description: A bilingual primary school has initiated a project to address the “transition challenge” the children at the school, all of whom have bilingual classes from the start of Year One on, will face in the subject English when they go to secondary school. Working with researchers, a teacher from the school is developing a flexible, easily adaptable self-assessment portfolio that learners are able to present at secondary school so that their new English teachers can build on what the children have learnt and can do. This contribution relates some of the decisions and experiences this project-in-progress entailed in its first implementation with children in Years One and Two. For example, the project team observed informally that working with the portfolio and reflecting on their learning process and progress promotes the children’s agency and autonomy. While the portfolio is a practical instrument initiated at grassroots level, the data gathered are undoubtedly of interest to researchers and provide evidence of the benefits of starting English in Year One, and of an inclusive, across-the-board, immersive bilingual policy.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Vol 2 No 4 (2020): Standards – Margins – New Horizons. Teaching Language and Literature in the 21st Century
Möglichkeiten der Sprachförderung durch Lateinunterricht angesichts einer heterogenen Schülerschaft
Creators: name: Kuhlmann, Peter
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2020

description: Sprachförderung stellt heute in Deutschland eine besondere Herausforderung für die Schule dar: Zum einen weisen immer mehr Schüler*innen einen Migrationshintergrund auf und sprechen zu Hause eine andere Sprache als Deutsch. Zum anderen sind auch viele junge deutsche Muttersprachler*innen nicht zuletzt aufgrund der Nutzung elektronischer Medien heute sprachlich anders sozialisiert als in früheren Zeiten. Insbesondere die Normen der schriftlichen Standardsprache spielen im Alltag heutiger Schüler*innen eine zunehmend geringere Rolle. Im Lateinunterricht durchlaufen die Lernenden von Anfang an einen systematischen Durchgang durch das lateinische Sprachsystem, das wiederum stets mit der deutschen Zielsprache kontrastiert wird. Auch durch das Verfahren des Übersetzens werden Lernende mit den Normen der Zielsprache konfrontiert und können diese einüben. Die Vermittlung von metasprachlichen Kategorien kann zudem bei der Ausbildung von Sprachbewusstheit und Sprachreflexion helfen. Im Beitrag werden einige zentrale Aspekte einer solchen Sprachförderung aufgezeigt – v.a. am Beispiel besonderer schriftsprachlicher Kategorien im Deutschen (z.B. Genitiv, Konjunktiv, Präteritum).
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Vol 2 No 4 (2020): Standards – Margins – New Horizons. Teaching Language and Literature in the 21st Century
Robotic milling : A five axis milling alternative
Creators: name: Miller, Logan
name: Rice, Zachary
Publisher: name: Unknown
Year: 2019

description: The project was requested to develop a proof of concept system for robotic milling utilizing
available small robots in the Applied Engineering Center. The project included procuring a
milling spindle and variable frequency drive (VFD) appropriately sized for the spindle.
Designing and fabricating of mounting hardware for spindle and work piece will be needed.
Development of a test work piece, cnc code for milling operations of workpiece, and finally use
an offline programming software to develop robotic program for milling.
Electronic Supplementary Material from In that vein: inflated wing veins contribute to butterfly hearing
Creators: name: Penghui Sun
name: Mhatre, Natasha
name: Mason, Andrew
name: Yack, Jayne
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Neuroscience
subject: 110601 Biomechanics
subject: FOS: Health sciences
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Supplementary Methods and Results are provided in this file. This file includes four figures and two tables that are referred to in the main body of the text.
Cardiac Reentry Modeled by Spatiotemporal Chaos in a Coupled Map Lattice
Creators: name: Stenzinger, R. V.
name: Tragtenberg, M. H. R.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: Chaotic Dynamics (nlin.CD)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling is an important tool to fill this gap. Typical studies often employ detailed multidimensional conductance-based models. We describe the cardiac muscle with a three-dimensional map-based membrane potential model in lattices. Although maps retain the biophysical behavior of cells and generate computationally efficient tissue models, few studies have used them to understand cardiac dynamics. Our study captures healthy and pathological behaviors with fewer parameters and simpler equations than conductance models. We successfully generalize results obtained previously with reaction-diffusion systems, showing how chaotic properties result in reentry, a pathological propagation of stimuli that evolves to arrhythmias with complex spatiotemporal features. The bifurcation diagram of the single cell is very similar to that obtained in a detailed conductance-based model. We find torsade de pointes, a clinical manifestation of some types of tachycardia in the electrocardiogram, using a generic sampling of the whole network during spiral waves. We also find a novel type of dynamical pattern, with wavefronts composed of synchronized cardiac plateaus and bursts. Our study provides the first in-depth look at the use of map-based models to simulate complex cardiac dynamics.
description: 15 pages, 9 figures. Eur. Phys. J. Spec. Top. (2022)
Supplemental text from On critical dynamics and thermodynamic efficiency of urban transformations.
Creators: name: Crosato, Emanuele
name: Nigmatullin, Ramil
name: Prokopenko, Mikhail
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 80201 Analysis of Algorithms and Complexity
subject: FOS: Computer and information sciences

description: This document contains additional information about data sources, methods and results.
Sensor and actuator module for the PLC trainer : Final report
Creators: name: Knowles, Paige
name: Walker, Jonathan
Publisher: name: Unknown
Year: 2019

description: SCADA Systems Design is a course that teaches students to control industrial processes
using Programmable Logic Controllers (PLCs). Previously, in the SCADA course at the
University of Southern Indiana, the only visual proof of code success available on the
PLC trainer were relay indicators and LEDs. A module was needed that included
actuators and a variety of feedback sensors to expand the physical inputs and outputs
available on the trainers. This project designs, implements, and tests an add-on module
to give the users of the PLC trainers these experiences. The final module includes three
actuators and five feedback sensors, that give students a variety of test methods towards
understanding control of PLCs.