cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A gyrokinetic model for the plasma periphery of tokamak devices
Creators: name: Frei, B. J.
name: Jorge, R.
name: Ricci, P.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: A gyrokinetic model is presented that can properly describe strong flows, large and small amplitude electromagnetic fluctuations occurring on scale lengths ranging from the electron Larmor radius to the equilibrium perpendicular pressure gradient scale length, and large deviations from thermal equilibrium. The formulation of the gyrokinetic model is based on a second order description of the single charged particle dynamics, derived from Lie perturbation theory, where the fast particle gyromotion is decoupled from the slow drifts, assuming that the ratio of the ion sound Larmor radius to the perpendicular equilibrium pressure scale length is small. The collective behavior of the plasma is obtained by a gyrokinetic Boltzmann equation that describes the evolution of the gyroaveraged distribution function and includes a non-linear gyrokinetic Dougherty collision operator. The gyrokinetic model is then developed into a set of coupled fluid equations referred to as the gyrokinetic moment hierarchy. To obtain this hierarchy, the gyroaveraged distribution function is expanded onto a velocity-space Hermite-Laguerre polynomial basis and the gyrokinetic equation is projected onto the same basis, obtaining the spatial and temporal evolution of the Hermite-Laguerre expansion coefficients. The Hermite-Laguerre projection is performed accurately at arbitrary perpendicular wavenumber values. Finally, the self-consistent evolution of the electromagnetic fields is described by a set of gyrokinetic Maxwell's equations derived from a variational principle, with the velocity integrals of the gyroaveraged distribution function explicitly evaluated.
Fabric along the NEEM ice core, Greenland, and its comparison with GRIP and NGRIP ice cores
Creators: name: Montagnat, M.
name: Azuma, N.
name: Dahl-Jensen, D.
name: Eichler, J.
name: Fujita, S.
name: Gillet-Chaulet, F.
name: Kipfstuhl, S.
name: Samyn, D.
name: Svensson, A.
name: Weikusat, I.
Publisher: name: Freie Universität Berlin
Year: 2014
Subjects: subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie

description: Fabric (distribution of crystallographic orientations) along the full NEEM ice core, Greenland was measured in the field by an automatic ice texture analyzer every 10 m, from 33 m down to 2461 m depth. The fabric evolves from a slightly anisotropic fabric at the top, toward a strong single maximum at about 2300 m, which is typical of a deformation pattern mostly driven by uniaxial compression and simple shearing. A sharp increase in the fabric strengthening rate is observed at the Holocene to Wisconsin (HW) climatic transition. From a simple model we estimate that this depth is located at a transition from a state dominated by vertical compression to a state dominated by vertical shear. Comparisons are made to two others ice cores drilled along the same ridge; the GRIP ice core, drilled at the summit of the ice sheet, and the NGRIP ice core, drilled 325 km to the NNW of the summit along the ridge, and 365 km upstream from NEEM. This comparison tends to demonstrate that the ice viscosity change with the HW climatic transition must be associated with the shear-dominated state to induce the abrupt fabric strengthening observed at NEEM. This comparison therefore reflects the increasing role of shear deformation on the coring site when moving NW along the ridge from GRIP to NGRIP and NEEM. The difference in fabric profiles between NEEM and NGRIP also evidences a stronger lateral extension associated with a sharper ridge at NGRIP. Further along the core, centimeter scale abrupt texture (fabric and microstructure) variations are observed in the bottom part of the core. Their positions are in good agreement with the observed folding layers in Dahl- Jensen et al. (2013).
title: Allegretto Vivace. Omaggio a Bruna Donatelli
Creators: name: Arciero, Angelo
Publisher: name: Roma TrE-Press
Year: 2021

description: La nota fondamentale di questo volume, che un gruppo di amici e colleghi dedicano a Bruna Donatelli, è la questione dell’intermedialità, che i vari saggi in esso raccolti declinano in modi molteplici. Si parla dei tipi più diversi di riadattamento (dalla letteratura al cinema, al fumetto, al graphic novel, o anche dal saggio estetico alla sequenza cinematografica). Si analizza la scrittura etnografica come forma di «rimediazione», si propone l’analisi di fototesti come pure si scruta lo sguardo filmico di scrittori dell’era pre-cinematografica. Si riflette sugli intrecci tra parola e scrittura, oppure sulla critica d’arte come forma di scrittura intermediale. Si discute di censura, di fotografia metaforica e di processi di ricezione. Gli autori dei vari contributi fanno parlare scrittori e artisti i più diversi: si va da Lawrence Sterne a Lars von Trier, da Chateaubriand a Orwell, a Wagner, a Henry James, a Manuel Puig. Ma ci sono anche il fotografo George Tatge e l’antropologo Marcel Griaule, ci sono i registi della Nouvelle Vague, e poi Proust, Yves Bonnefoy, Boris Diop, e non da ultimo Flaubert, un autore molto amato e frequentato da Bruna Donatelli.
description: Allegretto Vivace. Omaggio a Bruna Donatelli
Local smooth solutions of the nonlinear Klein-gordon equation
Creators: name: Cazenave, Thierry
name: Naumkin, Ivan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: Primary 35L70, secondary 35L60, 35A01, 35B65

description: Given any $μ_1, μ_2\in {\mathbb C}$ and $α>0$, we prove the local existence of arbitrarily smooth solutions of the nonlinear Klein-Gordon equation $\partial_{ tt } u - Δu + μ_1 u = μ_2 |u|^αu$ on ${\mathbb R}^N$, $N\ge 1$, that do not vanish, i.e. $ |u (t,x) | >0 $ for all $x \in {\mathbb R}^N$ and all sufficiently small $t$. We write the equation in the form of a first-order system associated with a pseudo-differential operator, then use a method adapted from~[Commun. Contemp. Math. {\bf 19} (2017), no. 2, 1650038]. We also apply a similar (but simpler than in the case of the Klein-Gordon equation) argument to prove an analogous result for a class of nonlinear Dirac equations.
Additional file 6: of Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Creators: name: Costa, Elodie Da
name: Armaos, Gregory
name: McInnes, Gabrielle
name: Beaudry, Annie
name: Moquin-Beaudry, Gaël
name: Bertrand-Lehouillier, Virginie
name: Caron, Maxime
name: Richer, Chantal
name: St-Onge, Pascal
name: Johnson, Jeffrey
name: Nevan Krogan
name: Sai, Yuka
name: Downey, Michael
name: Moutih Rafei
name: Boileau, Meaghan
name: Eppert, Kolja
name: Flores-Díaz, Ema
name: Haman, André
name: Hoang, Trang
name: Sinnett, Daniel
name: Beauséjour, Christian
name: McGraw, Serge
name: Raynal, Noël
Publisher: name: figshare
Year: 2019
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Figure S5. H3K27 Acetylation DNA Occupancy Is Lost After Proscillaridin A Treatment In MOLT-4 Cells. Metascape analysis of A downregulated genes and B upregulated genes after proscillaridin A treatment (5 nM; 48h) marked by H3K27ac in their promoter regions (-500 bp / +500 bp). (PDF 657 kb)
AtlantECO Deliverable D4.8 - Report on technology advancement
Creators: name: Robidart, Julie
Publisher: name: Zenodo
Year: 2022

description: Deliverable 4.8 reports on the technological innovations planned as part of Task 4.3.  These are based on two existing prototypes, which use in the marine environment has been previously demonstrated: (1) the Underwater Vision Profiler (UVP6-LP), and (2) the Robotic Cartridge Sampling Instrument (RoCSI, previously MAPS). The objectives of AtlantECO required further developments of these two devices to meet the needs of various science and industry stakeholders, and their deployment on a range of sampling platforms, such as a) aquaculture facilities, b) ships, sampling the underway system of a ship while towing the Continuous Plankton Recorder, c) in the deep sea for sustained operations, d) on free drifting Argo floats, and e) on moored sediment traps.

 

The Technology Readiness Level of four such applications are reported here. Two high-resolution imaging sensors (UVP6-LP) and an Argo float (NKE float) were purchased, and significant progress was made with the design and construction of free-drifting and moored instruments that combine sediment traps and the UVP6-LP. The RoCSI underwent extensive pressure testing and was upgraded for improved performance at depths up to 4500m. The upgrades increased ease of manufacturing and reduced the footprint by 100mm. This system was tested without any failure on RSS James Cook expedition 237 in August 2022 during transit, while towing the CPR.

 

This document is based on the terms and conditions established in the Grant Agreement (GA) and its Annexes, as well as in the Consortium Agreement (CA).
Quantum Z-algebras and representations of quantum affine algebras
Creators: name: Jing, Naihuan
Publisher: name: arXiv
Year: 1998
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 17B

description: Generalizing our earlier work, we introduce the homogeneous quantum $Z$-algebras for all quantum affine algebras $\alg$ of type one. With the new algebras we unite previously scattered realizations of quantum affine algebras in various cases. As a result we find a realization of $U_q(F_4^{(1)})$.
description: 16 pages, AMSTEX
Twistor Bundles, Einstein Equations and Real Structures
Creators: name: Nurowski, P.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We consider sphere bundles P and P' of totally null planes of maximal dimension and opposite self-duality over a 4-dimensional manifold equipped with a Weyl or Riemannian geometry. The fibre product PP' of P and P' is found to be appropriate for the encoding of both the selfdual and the Einstein-Weyl equations for the 4-metric. This encoding is realized in terms of the properties of certain well defined geometrical objects on PP'. The formulation is suitable for both complex- and real-valued metrics. It unifies results for all three possible real signatures. In the purely Riemannian positive definite case it implies the existence of a natural almost hermitian structure on PP' whose integrability conditions correspond to the self-dual Einstein equations of the 4-metric. All Einstein equations for the 4-metric are also encoded in the properties of this almost hermitian structure on PP'.
description: Paper accepted in Classical and Quantum Gravity, Special issue in honour of Professor Andrzej Trautman
Composition sum identities related to the distribution of coordinate values in a discrete simplex
Creators: name: Milson, Robert
Publisher: name: arXiv
Year: 2000
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05A19, 05A20

description: Utilizing spectral residues of parameterized, recursively defined sequences, we develop a general method for generating identities of composition sums. Specific results are obtained by focusing on coefficient sequences of solutions of first and second order, ordinary, linear differential equations. Regarding the first class, the corresponding identities amount to a proof of the exponential formula of labelled counting. The identities in the second class can be used to establish certain geometric properties of the simplex of bounded, ordered, integer tuples. We present three theorems that support the conclusion that the inner dimensions of such an order simplex are, in a certain sense, more ample than the outer dimensions. As well, we give an algebraic proof of a bijection between two families of subsets in the order simplex, and inquire as to the possibility of establishing this bijection by combinatorial, rather than by algebraic methods.
description: AMSLatex, 16 pages
PEPSI++: Fast and Lightweight Network for Image Inpainting
Creators: name: Shin, Yong-Goo
name: Sagong, Min-Cheol
name: Yeo, Yoon-Jae
name: Kim, Seung-Wook
name: Ko, Sung-Jea
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Image and Video Processing (eess.IV)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Among the various generative adversarial network (GAN)-based image inpainting methods, a coarse-to-fine network with a contextual attention module (CAM) has shown remarkable performance. However, owing to two stacked generative networks, the coarse-to-fine network needs numerous computational resources such as convolution operations and network parameters, which result in low speed. To address this problem, we propose a novel network architecture called PEPSI: parallel extended-decoder path for semantic inpainting network, which aims at reducing the hardware costs and improving the inpainting performance. PEPSI consists of a single shared encoding network and parallel decoding networks called coarse and inpainting paths. The coarse path produces a preliminary inpainting result to train the encoding network for the prediction of features for the CAM. Simultaneously, the inpainting path generates higher inpainting quality using the refined features reconstructed via the CAM. In addition, we propose Diet-PEPSI that significantly reduces the network parameters while maintaining the performance. In Diet-PEPSI, to capture the global contextual information with low hardware costs, we propose novel rate-adaptive dilated convolutional layers, which employ the common weights but produce dynamic features depending on the given dilation rates. Extensive experiments comparing the performance with state-of-the-art image inpainting methods demonstrate that both PEPSI and Diet-PEPSI improve the qualitative scores, i.e. the peak signal-to-noise ratio (PSNR) and structural similarity (SSIM), as well as significantly reduce hardware costs such as computational time and the number of network parameters.
description: Accepted to IEEE transactions on Neural Networks and Learning Systems. To be published
Development of a MEMS Sensor for sub-kPa Shear Stress Measurements
Creators: O'Grady, Andrew
Publisher: name: Columbia University
Year: 2011
Subjects: subject: Mechanical engineering
subject: FOS: Mechanical engineering

description: This dissertation discusses the development of MEMS sensors for measuring sub-kPa (<1000Pa) wall shear stresses in high-speed turbulent flows. Wall shear stress is an important flow quantity that is used to characterize flows that can be found in aerospace, automotive, and biomedical applications. Sensors that can measure this quantity could have many uses ranging from pure turbulence research to flow control of vehicles. MEMS fabrication techniques allow for the creation of micro-scale sensors that are small enough to accurately measure fluctuating turbulent shear stress. Utilizing a direct-shear stress measurement with a floating element allows the sensors to be calibrated in a well-known shear flow before being installed in an unknown flow environment. The sensors use a differential capacitance measurement scheme combined with non-intrusive backside sensor connections, allowing measurements in recirculating and separating flows. As part of the sensor design process, 36 different sensor designs were created with varying feature sizes and performance ranges. This was done to mitigate the risks inherent in MEMS fabrication processes and to increase the chances of developing working sensors which could operate in the desired shear stress range (1 - 1000Pa). The sensors were fabricated with the floating element in the top layer of an SOI wafer, with thru-wafer electrical interconnects (vias) created to connect the frontside of the sensor to the backside of the chip. Post-fabrication, the sensors were characterized electrically and mechanically under a microscope probe station. Sensors were then installed in a custom-made package which integrated off-the-shelf capacitance measuring circuitry with the MEMS sensor. Using a subsonic duct flow setup, sensors were calibrated in compressible turbulent air flow up to a mean shear stress of 335Pa and a friction velocity Re value of 200,000. After numerical temperature compensation was implemented (required due to temperature-dependent material properties) the sensor gain was calculated as 0.16mV/Pa. The mean shear stress calibration was then used to analyze the turbulence fluctuations inherent in the sensor signal. Turbulence measurements (including intensity, spectral density, and probability density function) indicated that the sensors were responding to shear stress fluctuations, but not detecting the entire turbulent energy spectrum due to low-pass filtering caused by the electrical circuitry. Experimental measurement of wall shear stress in compressible turbulent flows is an area that has not been fully explored due to previous limitations in available measurement technology. Once a better understanding is gained of the operation and limitations of the MEMS wall shear stress sensors, there lies a great potential to increase our understanding of turbulent flows with unprecedented measurements.
New developments of photodetectors for the Lake Baikal Neutrino Experiment
Creators: name: Lubsandorzhiev, B. K.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: New developments of photodetectors for the lake Baikal neutrino experiment are described. Some test results of photodetectors at the lake Baikal are presented.
description: 6 pages, 3 figures, talk at 7th International Conference on Advanced Technology and Particle Physics, Villa Olmo, Como 15-19 October 2001
Financing Hope: Persons Living with Rare Diseases in Singapore
Creators: name: Ng Qin Xiang,
name: Clarence Ong,
Publisher: name: National University of Singapore
Year: 2024
Subjects: Singapore
healthcare financing
rare diseases
crowdfunding
risk sharing
Australia
United Kingdom
United States
South Korea

description: This case study focuses on the financial challenges and policy implications of treating rare diseases in Singapore, using the story of Devdan, a 22-month-old living with spinal muscular atrophy (SMA). A promising novel treatment for SMA, Zolgensma®, is approved for use in Singapore but priced at S$2.9 million, which is out of reach for most. With few financing options, families often have to turn to community crowdfunding. Singapore’s Rare Disease Fund (RDF), established in 2019, whilst matching government contributions and public donations, offers limited coverage for patients and families. A comparative analysis with Australia, the United Kingdom, the United States, and South Korea reveals different approaches to funding rare diseases. These include government-supported reimbursements, specialized funds like Australia’s Life Saving Drugs Program (LSDP) and the UK’s Innovative Medicines Fund (IMF), and private insurance models in the US. Leveraging on existing infrastructure and biomedical expertise, Singapore could establish risk-sharing agreements with pharmaceutical companies and contemplate the creation of a rare disease investment fund, which blends private investment and government support. Devdan’s case led to a very successful crowdfunding campaign, highlighting the power of community support. However, it also underscores the need for more sustainable and inclusive solutions for rare diseases locally.
Additional file 1 of Coordination of m6A mRNA methylation and gene transcriptome in rice response to cadmium stress
Creators: name: Cheng, Qin
name: Wang, Peng
name: Wu, Guangliang
name: Wang, Yanning
name: Tan, Jingai
name: Li, Caijing
name: Zhang, Xiangyu
name: Liu, Shilei
name: Huang, Shiying
name: Huang, Tao
name: Yang, Mengmeng
name: He, Haohua
name: Bian, Jianmin
Publisher: name: figshare
Year: 2021
Subjects: subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 1:
The Impact of Thailand-Australia Free Trade Agreement (TAFTA): Akara Mining Dispute between the Thai Government and Kingsgate Consolidated Limited
Creators: name: Pattanun Arunpreechawat,
name: Muzi Li,
name: Jinjuta Masook,
Publisher: name: National University of Singapore
Year: 2024
Subjects: Thailand
Australia
free trade agreements
environment
foreign companies
local communitiesinvestor-state dispute settlement
mining
Kingsgate
human rights

description: This study aims to explore how Free Trade Agreements (FTAs) bring multiple benefits but also generate negative impacts on people and the environment. The mining dispute between an Australia-based mining company, Kingsgate Consolidated Limited, and the Thai government well encapsulates various dimensions of free trade agreements, particularly the imbalanced power dynamic between the foreign companies protected by FTAs and the local communities and the environment. Through Thailand-Australia Free Trade Agreement (TAFTA), Kingsgate received a concession from the Thai government to mine gold in three provinces: Phichit, Phitsanulok, and Phetchabun. Although various stakeholders welcomed the economic boost and job creation, adverse effects on the local communities, ranging from relocations, job losses in agricultural sectors, and violations of the locals’ human rights to the contamination of the environment with poisonous substances, were inevitable. The government then suspended the mining operation, which later faced a lawsuit filed by Kingsgate through Investor-State Dispute Settlement (ISDS), a privilege from TAFTA granting private parties the right to sue a nation. Although the legal proceedings with Kingsgate for the resumption of mining operations in 2023 are progressing, Thailand continues grappling with the persistent challenges of mitigating the negative externalities caused by TAFTA.
Everettia jucunda sensu Pfeiffer 1863
Creators: name: Liew, Thor-Seng
name: Schilthuizen, Menno
name: Vermeulen, Jaap Jan
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Dyakiidae
Everettia
Everettia jucunda

description: 1 Everettia jucunda 0 3 2
2
 3 Everettia subconsul 12 4 2
4
5
6
7
8
9
10
11
 12 Everettia themis 2 4 2
13
14
 15 Everettia 2 1 2 klemmatanica
 16 Everettia corrugata 11 4 1 corrugata
17
18
 19 Everettia corrugata 4 1 1 williamsi
 20 Everettia 4 3 layanglayang
21
22
23
24
 25 Everettia lapidini 2 3 2
description: Published as part of Liew, Thor-Seng, Schilthuizen, Menno & Vermeulen, Jaap Jan, 2009, Systematic revision of the genus Everettia Godwin-Austen, 1891 (Mollusca: Gastropoda: Dyakiidae) in Sabah, northern Borneo, pp. 515-550 in Zoological Journal of the Linnean Society 157 (3) on page 517, DOI: 10.1111/j.1096-3642.2009.00526.x, http://zenodo.org/record/5443023
Cooking or Cooked: The Future of Singapore’s Hawking Culture
Creators: name: Khor Jia Wei,
name: Kenneth Tan Zhe Kai,
Publisher: name: National University of Singapore
Year: 2024
Subjects: Singapore
hawker centres
hawker policies
hawker food prices
hawker culture
mindset change

description: Singapore prides itself on its world-renowned hawker culture. Yet, decades of culinary expertise are at risk of fading. This paper will first examine the two main problems faced by the hawker industry, namely, the diminishing profit margins and low replacement rates of hawkers in the industry. In doing so, the various factors that contribute to the narrow profit margins and low replacement rates will also be explored. Secondly, the case study will analyse the four main policy approaches that the Singapore government has implemented. The case will situate the policy approaches based on its purpose, stakeholder, and time horizon. Lastly, the case will evaluate and critique the efficacy of the policy in addressing the multifaceted nature of the problem. At its core, this paper serves as an example of how even a comprehensive suite of policies will not be able to effectively resolve a problem if the underlying issue of culture and people’s mindset are not changed. Perhaps, there is a limit in terms of public policy and more needs to be done to influence and shift the ingrained mindsets of citizens. Only then will there truly be a sustainable solution to the problem.
Additional file 5: of Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Creators: name: Costa, Elodie Da
name: Armaos, Gregory
name: McInnes, Gabrielle
name: Beaudry, Annie
name: Moquin-Beaudry, Gaël
name: Bertrand-Lehouillier, Virginie
name: Caron, Maxime
name: Richer, Chantal
name: St-Onge, Pascal
name: Johnson, Jeffrey
name: Nevan Krogan
name: Sai, Yuka
name: Downey, Michael
name: Moutih Rafei
name: Boileau, Meaghan
name: Eppert, Kolja
name: Flores-Díaz, Ema
name: Haman, André
name: Hoang, Trang
name: Sinnett, Daniel
name: Beauséjour, Christian
name: McGraw, Serge
name: Raynal, Noël
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Figure S4. Histone Methylation Is Not Significantly Altered After Proscillaridin A Treatment On Histone H3. MOLT-4 (A) and NALM-6 (B) cells were treated with proscillaridin A (5 nM) and histones were acid-extracted after 8, 16, 24, 48, 72 and 96 hours. Histone 3 methylation levels were assessed using antibodies against K4me3, K9me3, and K27me3. H3 was used as loading control. H3 methylation levels were quantified and expressed as a percentage of untreated cells (Two-way ANOVA; n = 3). C Confocal microscopy (60X) of MOLT-4 cells stained with DAPI revealed heterochromatin modulation after proscillaridin A treatment (5 nM; 48h). White arrows indicate loss of heterochromatin regions. (PDF 1592 kb)
Skew Schubert functions and the Pieri formula for flag manifolds
Creators: name: Bergeron, Nantel
name: Sottile, Frank
Publisher: name: arXiv
Year: 1997
Subjects: subject: Algebraic Geometry (math.AG)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05E15 14M15

description: We show the equivalence of the Pieri formula for flag manifolds and certain identities among the structure constants, giving new proofs of both the Pieri formula and of these identities. A key step is the association of a symmetric function to a finite poset with labeled Hasse diagram satisfying a symmetry condition. This gives a unified definition of skew Schur functions, Stanley symmetric function, and skew Schubert functions (defined here). We also use algebraic geometry to show the coefficient of a monomial in a Schubert polynomial counts certain chains in the Bruhat order, obtaining a new combinatorial construction of Schubert polynomials.
description: 24 pages, LaTeX 2e, with epsf.sty
Influence of cap weight on the motion of a Janus particle very near a wall
Creators: name: Rashidi, Aidin
name: Razavi, Sepideh
name: Wirth, Christopher L.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The dynamics of anisotropic nano- to microscale colloidal particles in confined environments, either near neighboring particles or boundaries, is relevant to a wide range of applications. We utilized Brownian dynamics simulations to predict the translational and rotational fluctuations of a Janus sphere with a cap of non-matching density. The presence of the cap significantly impacted the rotational dynamics of the particle as a consequence of gravitational torque at experimentally relevant conditions. Gravitational torque dominated stochastic torque for a particle > 1 micrometer in diameter and with a 20 nm thick gold cap. Janus particles at these conditions sampled mostly cap-down or quenched orientations. Although the results summarized herein showed that particles of smaller diameter (< 1 micrometer) with a thin gold coating (< 5 nm) behave similar to an isotropic particle, small increases in either particle diameter or coating thickness drastically quenched the polar rotation of the particle. Histogram landscapes of the separation distance from the boundary and orientation observations of particles with larger diameters or thicker gold coatings were mostly populated with quenched configurations. Finally, the histogram landscapes were inverted to obtain the potential energy landscapes, providing a path for experimental data to be interpreted.
A computational model for information value
Creators: name: Schaal, Markus
Publisher: name: Freie Universität Berlin
Year: 2000
Subjects: subject: network representation
subject: uncertain quantities
subject: information value
subject: 000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::003 Systeme

description: The estimation of information value will be a key issue for upcoming intelligent information systems, that not only provide information on request but deal with time-dependently varying information needs. Due to its subjective nature, information value cannot be computed and each individual has a different perception of what exactly is relevant to him. However, we propose a concept of information value and a computational model for its estimation. Our model is based upon the observation that information concerning the future can easily be divided into relevant and irrelevant information as long as the future is deterministic and well known. We use a network representation of uncertain quantities to model the uncertainty of the future. Information value is introduced as the likelihood of reaching a situation in the future where the information is relevant. The approach is demonstrated for the modelling of individual travel planning.
Quantification of Nematic Cell Polarity in Three-dimensional Tissues
Creators: name: Scholich, André
name: Syga, Simon
name: Morales-Navarrete, Hernán
name: Segovia-Miranda, Fabián
name: Nonaka, Hidenori
name: Meyer, Kirstin
name: de Back, Walter
name: Brusch, Lutz
name: Kalaidzidis, Yannis
name: Zerial, Marino
name: Jülicher, Frank
name: Friedrich, Benjamin M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: How epithelial cells coordinate their polarity to form functional tissues is an open question in cell biology. Here, we characterize a unique type of polarity found in liver tissue, nematic cell polarity, which is different from vectorial cell polarity in simple, sheet-like epithelia. We propose a conceptual and algorithmic framework to characterize complex patterns of polarity proteins on the surface of a cell in terms of a multipole expansion. To rigorously quantify previously observed tissue-level patterns of nematic cell polarity (Morales-Navarette et al., eLife 8:e44860, 2019), we introduce the concept of co-orientational order parameters, which generalize the known biaxial order parameters of the theory of liquid crystals. Applying these concepts to three-dimensional reconstructions of single cells from high-resolution imaging data of mouse liver tissue, we show that the axes of nematic cell polarity of hepatocytes exhibit local coordination and are aligned with the biaxially anisotropic sinusoidal network for blood transport. Our study characterizes liver tissue as a biological example of a biaxial liquid crystal. The general methodology developed here could be applied to other tissues or in-vitro organoids.
description: 27 pages, 9 color figures
Discontinuous Galerkin Finite Element Methods for the Landau-de Gennes Minimization Problem of Liquid Crystals
Creators: name: Maity, Ruma Rani
name: Majumdar, Apala
name: Nataraj, Neela
Publisher: name: arXiv
Year: 2019
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65N30, 35J60, 35J15

description: We consider a system of second order non-linear elliptic partial differential equations that models the equilibrium configurations of a two dimensional planar bistable nematic liquid crystal device. Discontinuous Galerkin finite element methods are used to approximate the solutions of this nonlinear problem with non-homogeneous Dirichlet boundary conditions. A discrete inf-sup condition demonstrates the stability of the discontinuous Galerkin discretization of a well-posed linear problem. We then establish the existence and local uniqueness of the discrete solution of the non-linear problem. An a priori error estimate in the energy norm is derived and a best approximation property is demonstrated. Further, we prove the quadratic convergence of Newton's iterates along with complementary numerical experiments.
description: 27 pages, 23 figures
Twisted L^2 invariants of non-simply connected manifolds
Creators: name: Mathai, Varghese
name: Shubin, Mikhail
Publisher: name: arXiv
Year: 1996
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 58 (Primary)

description: We develop the theory of twisted L^2-cohomology and twisted spectral invariants for flat Hilbertian bundles over compact manifolds. They can be viewed as functions on the first de Rham cohomology of M and they generalize the standard notions. A new feature of the twisted L^2-cohomology theory is that in addition to satisfying the standard L^2 Morse inequalities, they also satisfy certain asymptotic L^2 Morse inequalities. These reduce to the standard Morse inequalities in the finite dimensional case, and when the Morse 1-form is exact. We define the extended twisted L^2 de Rham cohomology and prove the asymptotic L^2 Morse-Farber inequalities, which give quantitative lower bounds for the Morse numbers of a Morse 1-form on M.
description: AMS-LaTeX v1.2, 28 pages, to appear in special issue of Russ.Jour.of Math.Physics
Additional file 4: of Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Creators: name: Costa, Elodie Da
name: Armaos, Gregory
name: McInnes, Gabrielle
name: Beaudry, Annie
name: Moquin-Beaudry, Gaël
name: Bertrand-Lehouillier, Virginie
name: Caron, Maxime
name: Richer, Chantal
name: St-Onge, Pascal
name: Johnson, Jeffrey
name: Nevan Krogan
name: Sai, Yuka
name: Downey, Michael
name: Moutih Rafei
name: Boileau, Meaghan
name: Eppert, Kolja
name: Flores-Díaz, Ema
name: Haman, André
name: Hoang, Trang
name: Sinnett, Daniel
name: Beauséjour, Christian
name: McGraw, Serge
name: Raynal, Noël
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Plant Biology

description: Figure S3. Proscillaridin A Induced Histone 3 Acetylation Loss In MOLT-4 And NALM-6 Cells. A MOLT-4 cells were treated with proscillaridin A (5 nM) and histones were acid-extracted after 8, 16, 24, 48, 72 and 96 hours. H3 acetylation levels were quantified and expressed as a percentage of untreated cells (* indicates P<0.05; Two-way ANOVA; n = 3). B Ratio of chromatin immunoprecipitation (ChIP) of H3K27 acetylation in MOLT-4 cells before and after proscillaridin A treatment (5 nM; 48h) (*indicates P<0.001; paired t-test, n=3). C NALM-6 cells were treated with proscillaridin A (5 nM) and histones were acid-extracted after 8, 16, 24, 48, 72 and 96 hours. H3 acetylation levels were quantified and expressed as a percentage of untreated cells (* indicates P<0.05; Two-way ANOVA; n = 3). D MOLT-4 and E NALM-6 cells were treated with proscillaridin A (5 nM) and histones were acid-extracted after 8, 16, 24, 48, 72 and 96 hours. Histone 4 acetylation levels were assessed using antibodies against K5ac, K8ac, K16ac, K20ac, and total histone 4 acetylation. H4 was used as loading control. H4 acetylation levels were quantified and expressed as a percentage of untreated cells (* indicates P<0.05; Two-way ANOVA; n = 3). (PDF 567 kb)
Everettia interior Liew & Schilthuizen & Vermeulen 2009
Creators: name: Liew, Thor-Seng
name: Schilthuizen, Menno
name: Vermeulen, Jaap Jan
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Dyakiidae
Everettia
Everettia interior

description: 26 Everettia interior 3 3 2
27
 28 Everettia 2 2 paulbasintali
 2 Beaufort, Klias
P. Tiga
2 Mt Tambuyukon eastern slope, 1100 m S114 Crocker Range, Ulu Membakut
Crocker Range, Ulu Membakut
Crocker Range, Kimanis 14–16 km, SP12529 Crocker Range, Kimanis 14–16 km, SP12529 Danum Valley CC
Nalapak Substesen Kinabalu
Nalapak Substesen Kinabalu
Kota Kinabalu, Pulau Gaya
1 Crocker Range TBC tower sp12599
 Mt Kinabalu southern slope, c. 1500 m
 Mt Kinabalu southern slope, c. 1900 m
 2 Mt Kinabalu southern slope, c. 1700 m
1 Mt Kinabalu north-western slope, 3000 m S142 Mt Kinabalu southern slope, 3100 m S14 Mt Kinabalu southern slope, 3400 m S16
1 Mt Kinabalu south-eastern slope, 3100 m S69A
1 Mt Kinabalu north-western slope, S132 Mt Kinabalu south-eastern slope, S58 Mt Kinabalu southern slope, S11 Crocker Range, Gunung Alab (1800 m) Crocker Range, Gunung Alab (1800 m) SP12907
 1 Mt Kinabalu south-western slope, c. 1700 m, Marai Parai SP12924
 2 Sapulut, Batu Tinagas Sapulut, Batu Sanaron
2 Tawau Hills Park (HQ)  FJ160635  FJ160636 FJ160629 FJ160630 FJ160631 FJ160632 FJ160633 FJ160639 FJ160640 FJ160641 FJ160634 FJ160623 FJ160627 FJ160628 FJ160611
description: Published as part of Liew, Thor-Seng, Schilthuizen, Menno & Vermeulen, Jaap Jan, 2009, Systematic revision of the genus Everettia Godwin-Austen, 1891 (Mollusca: Gastropoda: Dyakiidae) in Sabah, northern Borneo, pp. 515-550 in Zoological Journal of the Linnean Society 157 (3) on page 517, DOI: 10.1111/j.1096-3642.2009.00526.x, http://zenodo.org/record/5443023
A “Super-Aged” Society: Defusing Singapore’s Demographic Time Bomb
Creators: name: Hannah Pang Jing Xuan,
Publisher: name: National University of Singapore
Year: 2024
Subjects: Singapore
ageing population
family planning
longevity
fertility
care work
child care
active ageing
ageism
technology

description: Prime Minister Lee Hsien Loong highlighted that nearly one in four Singaporeans will be a senior by 2030, making Singapore a “super-aged” society. Singapore is not just ageing, but doing so rapidly, posing various social and economic challenges for Singapore which need to be addressed by the government, in collaboration with various stakeholders. This case study begins by examining the history of family planning policies in Singapore, including the “Stop at Two” campaign. Thereafter, it highlights how increased longevity and lowered fertility rates have caused this “demographic time bomb”. It proceeds to evaluate existing measures that have been introduced in Singapore, focusing on mitigation strategies that work preemptively, including increasing care workers, expanding the workforce and increasing the population. Lastly, it explores alternative solutions implemented in other countries, and initiated in Singapore. These include increasing the accessibility of child care, improving care work, utilising technology, promoting active ageing and combatting ageism.
Development of a mouse model of a novel thin lissencephaly variant
Creators: Belarde, James Anthony
Publisher: name: Columbia University
Year: 2021
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Developmental biology
subject: Medicine
subject: Neurobiology
subject: Epilepsy--Pathophysiology
subject: Epilepsy--Genetic aspects
subject: Neocortex
subject: Intellectual disability--Etiology
subject: Lissencephaly
subject: Mice

description: The human neocortex is a highly sophisticated and organized brain structure that is thought to mediate some of the most complex cognitive functions in humans including language and abstract thought. As such, environmental and genetic insults to its normal structure or function can result in devastating neurological conditions including severe epilepsy and intellectual disability. Malformations of cortical development are an increasing collection of disorders that cause neocortical abnormalities due to impaired developmental processes. One recently identified disorder in this class is a thin lissencephaly variant (TLIS) associated with several mutations in the C-terminus death domain of the caspase-2 activation adaptor CRADD (also known as RAIDD). Beyond this, little is known about the mechanism underlying TLIS pathophysiology despite an increasing number of identified individuals suffering from it. In order to better understand this disorder, as well as the normal developmental mechanisms that are impaired in its pathogenesis, I have developed and characterized three murine models by introducing one of a number of different genetic perturbations associated with TLIS. These animal models show behavioral and biochemical abnormalities similar to those seen in human TLIS subjects. Focusing future studies on the developmental processes that underlie differences seen in these mouse models could greatly inform understanding of disease mechanism in humans and assist in the development in therapeutic interventions. My work presented in this dissertation thus effectively establishes a translationally relevant animal model of TLIS.
RF Chain Reduction for MIMO Systems: A Hardware Prototype
Creators: name: Gong, Tierui
name: Shlezinger, Nir
name: Ioushua, Shahar Stein
name: Namer, Moshe
name: Yang, Zhijia
name: Eldar, Yonina C.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Signal Processing (eess.SP)
subject: Information Theory (cs.IT)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Radio frequency (RF) chain circuits play a major role in digital receiver architectures, allowing passband communication signals to be processed in baseband. When operating at high frequencies, these circuits tend to be costly. This increased cost imposes a major limitation on future multiple-input multiple-output (MIMO) communication technologies. A common approach to mitigate the increased cost is to utilize hybrid architectures, in which the received signal is combined in analog into a lower dimension, thus reducing the number of RF chains. In this work we study the design and hardware implementation of hybrid architectures via minimizing channel estimation error. We first derive the optimal solution for complex-gain combiners and propose an alternating optimization algorithm for phase-shifter combiners. We then present a hardware prototype implementing analog combining for RF chain reduction. The prototype consists of a specially designed configurable combining board as well as a dedicated experimental setup. Our hardware prototype allows evaluating the effect of analog combining in MIMO systems using actual communication signals. The experimental study, which focuses on channel estimation accuracy in MIMO channels, demonstrates that using the proposed prototype, the achievable channel estimation performance is within a small gap in a statistical sense from that obtained using a costly receiver in which each antenna is connected to a dedicated RF chain.
Figure S1;Figure S2;Figure S3;Figure S4;Figure S5 from Smarter foragers do not forage smarter: a test of the diet hypothesis for brain expansion
Creators: name: Hirsch, Ben T.
name: Kays, Roland
name: Alavi, Shauhin
name: Caillaud, Damien
name: Havmoller, Rasmus
name: Mares, Rafael
name: Crofoot, Margaret
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified
classificationCode: 310901
subject: Animal behaviour
classificationCode: 520499
subject: Cognitive and computational psychology not elsewhere classified

description: Image of drone mapped fruiting Dipteryx trees from both study years on Barro Colorado Island with trail system mapped as brown lines;Number of Dipteryx trees (EMM- Estimated Marginal Means) encountered by simulations of random movement (OUF and BM) for four species compared to the observed number of Dipteryx visited per day. Black dots show average while purple shading shows standard deviation.;Raw path efficiency (A, C, E) and trackback adjusted path efficiency (B, D, E) by species for the period January 3rd - March 12. Full day results= A & B, first four hours of the day= C & D, first two hours of the day= E & F. Primates = green, Procyonids = blue. Average values per individual indicated by grey ○ = female, Δ = males. Mean and standard deviation indicated by black point and lines.;Estimated marginal means of coefficients for Species or Species*Sex, for path efficiency (A, C, E) and trackback adjusted path efficiency (B, D, E) for the period January 3rd - March 12. Full day results= A & B, first four hours of the day= C & D, first two hours of the day= E & F. Because the top model for the two-hour trackback adjusted efficiency included the species*sex interaction, figure S3F includes these marginal means.;Plots of the first derivative for the effect of Dipteryx density on path efficiency (A, C, E) and trackback adjusted path efficiency (B, D, E) for the period January 3rd - March 12. Full day results= A & B, first four hours of the day= C & D, first two hours of the day= E & F. Because zero is included in all posterior intervals, these graphs do not indicate statistically significant effects of Dipteryx density.
title: Targeting Breast Tumour-Initiating Cells with Vitamin E Analogues
Creators: name: Stantic, Marina
Publisher: name: Griffith University
Year: 2012
Subjects: subject: Malignant neoplasias
subject: Cancer
subject: Breast cancer
subject: Lung cancer
subject: Anti-cancer therapies
subject: Mitocans
subject: Vitamin E analogues

description: Cancer is the second biggest cause of death in the economically developed countries with breast cancer in females and lung cancer in males are the most frequently diagnosed tumours. Clinically referred to as malignant neoplasias, cancer is a combination of patho- logical states, all involving unregulated proliferation of cells in speficic locations. Over the last few years a new concept has emerged, suggesting that cancer is a disease driven by breast tumour-initiating cells (BTICs). Most current anti-cancer therapies used in clinical practice have the capability to reduce the tumour size, however they have detrimental side effects and also fail to target BTICs, a phenomenon that often leads to recurrence of tumours and disease relapse. The novel anti-cancer agents, referred to as mitocans are often selective for cancer cells while being non-toxic to normal cells and may have the propensity to induce apoptosis in tumour-initiator cells including BTICs. Our group has focused on two mitocans, -tocopheryl succinate and its mitochondrially targeted derivative MitoVES. While it has been documented that MitoVES is effective in a variety of cancer cells and in vivo mouse models of cancer, it has not been established what effects it has on BTICs and whether it acts by aiming at relevant molecular targets. The Thesis addresses these questions by establishing three aims, which are addressed in individual chapters. We have validated that the breast cancer cell line MCF7-derived mammospheres (MS) is a valid model to study the BTIC biology and resistance to apoptosis, as both phenotypical and genotypical features confirm increased level of stemness.