cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: Table S1. of Identification of miRNAs with potential roles in regulation of anther development and male-sterility in 7B-1 male-sterile tomato mutant
Creators: name: Omidvar, Vahid
name: Mohorianu, Irina
name: Dalmay, Tamas
name: Fellner, Martin
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: Science Policy
subject: Hematology
subject: Plant Biology

description: List of the identified known miRNAs in WT and 7B-1 anthers. Table S2. List of the new miRNAs identified from WT anthers. Table S3. List of the new miRNAs identified from 7B-1 anthers. Table S4. List of miRNA-target cleavage sites. Table S5. List of tasiRNAs and their predicated target genes. Table S6. List of the identified TAS3-derived tasiRNAs from WT library. Table S7. List of the identified TAS3-derived tasiRNAs from 7B-1 library. Table S8. List of the primers used for RT-qPCR analysis. Table S9. List of the primers used for 5â ˛-RACE analysis. Table S10. List of the DIG-labeled oligo-probes used for in situ hybridization. (DOCX 676Â kb)
title: Free charges versus excitons: photoluminescence investigation of InGaN/GaN multiple quantum well nanorods and their planar counterparts
Creators: name: Chen, Weijian
name: Wen, Xiaoming
name: Yang, Jianfeng
name: Latzel, Michael
name: Patterson, Robert
name: Huang, Shujuan
name: Shrestha, Santosh
name: Jia, Baohua
name: Moss, David J.
name: Christiansen, Silke H.
Publisher: name: Freie Universität Berlin
Year: 2018
Subjects: subject: multiple quantum well
subject: InGaN/GaN
subject: photoluminescence investigation
classificationCode: 530
subject: Physik

description: InGaN/GaN multiple quantum well (MQW) nanorods have demonstrated significantly improved optical and electronic properties compared to their planar counterparts. However, the exact nature of the processes whereby nanorod structures impact the optical properties of quantum wells is not well understood, even though a variety of mechanisms have been proposed. We performed nanoscale spatially resolved, steady-state, and time-resolved photoluminescence (PL) experiments confirming that photoexcited electrons and holes are strongly bound by Coulomb interactions (i.e., excitons) in planar MQWs due to the large exciton binding energy in InGaN quantum wells. In contrast, free electron–hole recombination becomes the dominant mechanism in nanorods, which is ascribed to efficient exciton dissociation. The nanorod sidewall provides an effective pathway for exciton dissociation that significantly improves the optical performance of InGaN/GaN MQWs. We also confirm that surface treatment of nanorod sidewalls has an impact on exciton dissociation. Our results provide new insights into excitonic and charge carrier dynamics of quantum confined materials as well as the influence of surface states.
Additional file 3: of The HAPPY (Healthy and Active Parenting Programmme for early Years) feasibility randomised control trial: acceptability and feasibility of an intervention to reduce infant obesity
Creators: name: McEachan, Rosemary
name: Santorelli, Gillian
name: Bryant, Maria
name: Pinki Sahota
name: Farrar, Diane
name: Small, Neil
name: Akhtar, Shaheen
name: Sargent, Judith
name: Barber, Sally
name: Taylor, Natalie
name: Richardson, Gerry
name: Farrin, Amanda
name: Bhopal, Raj
name: Bingham, Daniel
name: Ahern, Sara
name: Wright, John
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Additional data tables. (PDF 275Â kb)
Lecteria Osten Sacken 1888
Creators: name: Mederos, Jorge
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Limoniidae
Lecteria

description: KEY TO THE SPECIES OF THE SUBGENUS LECTERIA RECORDED FROM MITARAKA, FRENCH GUIANA (MALES ONLY):
1. Outer gonostylus divided in two small spike-shaped processes apically ........................................................ 2
— Outer gonostylus extending into a single decurved process at apex, with the outer apical angle featuring a rounded pale crest (Figs 1K; 4) ............................................................................................ Lecteria mitarakanea n. sp.
2. Interbase wide, trilobed with acute apices. Aedeagal complex (Fig. 7C) ............................. Lecteria teko n. sp.
— Interbase not trilobed, with a deep cleft in the central posterior margin. Aedeagal complex (Fig. 10B) ........... ..................................................................................................................................... Lecteria wayana n. sp.
description: Published as part of Mederos, Jorge & Pollet, Marc, 2019, Three new species of Lecteria Osten Sacken, 1888 (Diptera: Tipulidae) from a scientific survey in Mitaraka (French Guiana), pp. 497-512 in Zoosystema 41 (25) on page 511, DOI: 10.5252/zoosystema2019v41a25, http://zenodo.org/record/3726004
title: Cultural adaptation of Hap-pas-Hapi, an internet and mobile-based intervention for the treatment of psychological distress among Albanian migrants in Switzerland and Germany
Creators: name: Shala, Mirëlinda
name: Morina, Naser
name: Burchert, Sebastian
name: Cerga Pashoja, Arlinda
name: Knaevelsrud, Christine
name: Maercker, Andreas
name: Heim, Eva
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: Cultural adaptation
subject: E-mental health
subject: Psychological distress
subject: Self-help
subject: Minimally guided intervention
subject: Albanian-speaking migrants
classificationCode: 150
subject: Psychologie

description: Background: Internet- and mobile-based mental health interventions have the potential to narrow the treatment gap in ethnic groups. Little evidence exists on the cultural adaptation of such interventions. Cultural adaptation of evidence-based interventions distinguishes between surface and deep structure adaptation. Surface refers to matching materials (e.g., illustrations, language) or methods of treatment delivery to the target population, whereas deep structure adaptation considers cultural concepts of distress (CCD). So far, CCD have only been considered to a limited extent in cultural adaptation of psychological interventions, and there is a lack of well documented adaptation procedures. Aims: With a cross-disciplinary and mixed-method approach, following a new conceptual framework for cultural adaptation of scalable psychological interventions, this study aimed to develop both surface and deep structure adaptations of an internet- and mobile-based intervention called Hap-pas-Hapi for the treatment of psychological distress among Albanian migrants in Switzerland and Germany. Methods: A qualitative ethnopsychological study was conducted to examine the target group's CCD. Focus group discussions, an online survey, and individual key informant interviews were utilised to evaluate the original intervention, adaptation drafts and the final adapted intervention. A reporting system was developed to support the decision-making process and to report all adaptations in a transparent and replicable way. Results: The ongoing involvement of target population key informants provided valuable feedback for the development of a more person-centred intervention, which might enhance treatment acceptance, motivation and adherence. Discussion: This study provides empirical and theory-based considerations and suggestions for future implementation that may foster acceptability and effectiveness of culturally adapted evidence-based interventions.
Additional file 4: of New anti-cancer chemicals Ertredin and its derivatives, regulate oxidative phosphorylation and glycolysis and suppress sphere formation in vitro and tumor growth in EGFRvIII-transformed cells
Creators: name: Atsumi, Sonoko
name: Nosaka, Chisato
name: Hayamitsu Adachi
name: Kimura, Tomoyuki
name: Kobayashi, Yoshihiko
name: Takada, Hisashi
name: Watanabe, Takumi
name: Shun-Ichi Ohba
name: Inoue, Hiroyuki
name: Kawada, Manabu
name: Shibasaki, Masakatsu
name: Masabumi Shibuya
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Effect of Ertredin on HIF-1α protein levels under 3D or 2D conditions. Cells were cultured with the indicated substances for 24 h under 3D or 2D conditions. Sixteen micrograms of protein in each cell lysate were applied on SDS-PAGE and the HIF-1α protein level was estimated by western blotting. Dimethyloxaloylglycine (DMOG) is an inhibitor of prolyl hydroxylase (PHD) bringing that transports HIF-1α proteoasome systems. (PDF 235 kb)
Additional file 2: of The HAPPY (Healthy and Active Parenting Programmme for early Years) feasibility randomised control trial: acceptability and feasibility of an intervention to reduce infant obesity
Creators: name: McEachan, Rosemary
name: Santorelli, Gillian
name: Bryant, Maria
name: Pinki Sahota
name: Farrar, Diane
name: Small, Neil
name: Akhtar, Shaheen
name: Sargent, Judith
name: Barber, Sally
name: Taylor, Natalie
name: Richardson, Gerry
name: Farrin, Amanda
name: Bhopal, Raj
name: Bingham, Daniel
name: Ahern, Sara
name: Wright, John
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Measures â   Table of measures assessed at baseline, 6Â months and 12Â months. (PDF 297Â kb)
title: Climate change and cropland management compromise soil integrity and multifunctionality
Creators: name: Sünnemann, Marie
name: Beugnon, Remy
name: Breitkreuz, Claudia
name: Buscot, François
name: Cesarz, Simone
name: Jones, Arwyn
name: Lehmann, Anika
name: Lochner, Alfred
name: Orgiazzi, Alberto
name: Rillig, Matthias C.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Agroecology
subject: Climate-change ecology
subject: cropland management
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Soils provide essential ecosystem functions that are threatened by climate change and intensified land use. We explore how climate and land use impact multiple soil function simultaneously, employing two datasets: (1) observational – 456 samples from the European Land Use/Land Cover Area Frame Survey; and (2) experimental – 80 samples from Germany’s Global Change Experimental Facility. We aim to investigate whether manipulative field experiment results align with observable climate, land use, and soil multifunctionality trends across Europe, measuring seven ecosystem functions to calculate soil multifunctionality. The observational data showed Europe-wide declines in soil multifunctionality under rising temperatures and dry conditions, worsened by cropland management. Our experimental data confirmed these relationships, suggesting that changes in climate will reduce soil multifunctionality across croplands and grasslands. Land use changes from grasslands to croplands threaten the integrity of soil systems, and enhancing soil multifunctionality in arable systems is key to maintain multifunctionality in a changing climate.
Cavonus Sharp 1875
Creators: name: Hutchinson, Paul M.
name: Allsopp, Peter G.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dynastidae
Cavonus

description: Cavonus Sharp, 1875
Cavonus Sharp, 1875: 43. Type species: Cavonus armatus Sharp, 1875, by monotypy.
Coelothorax Ancey, 1880: 212; Blackburn 1888: 287 (synonymy). Type species: Coelothorax oberthuri Ancey, 1880, by monotypy.
Neocavonus Blackburn, 1888: 225; Carne 1957: 127 (synonymy). Type species: Neocavonus niger Blackburn, 1888, designated by Cassis & Weir (1992).
Comments. Blackburn (1888) included two species in Neocavonus, N. niger Blackburn, 1888, and N. occidentalis Blackburn, 1888, the latter albeit only with some hesitation, and did not designate either as the type species. He later (Blackburn 1896) added Neocavonus bidens Blackburn, 1896. Carne (1957) transferred N. occidentalis out of Neocavonus to Orthocavonus Carne, 1957 at the same time as he synonymised Neocavonus with Cavonus, retaining C. niger as the only species originally attributed to Neocavonus. This does not constitute a type fixation (Article 69.4, International Commission on Zoological Nomenclature 1999). However, the designation of N. niger as the type species by Cassis & Weir (1992) does fix it as the type species, although they incorrectly attributed this status to Blackburn (1888).
description: Published as part of Hutchinson, Paul M. & Allsopp, Peter G., 2020, Cavonus Sharp, 1875 (Coleoptera: Scarabaeidae: Dynastinae: Pentodontini Pseudoryctina) in Western Australia with description of a new species and the female of Cavonus sculpturatus Blackburn, 1888, pp. 449-460 in Zootaxa 4852 (4) on page 450, DOI: 10.11646/zootaxa.4852.4.3, http://zenodo.org/record/4410079
title: Understanding the electron-doping mechanism in potassium-intercalated single-walled carbon nanotubes
Creators: name: Kröckel, Claudia
name: Preciado-Rivas, María Rosa
name: Torres-Sánchez, Victor Alexander
name: Mowbray, Duncan J.
name: Reich, Stephanie
name: Hauke, Frank
name: Chacón Torres, Julio C.
name: Hirsch, Andreas
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: Chirality
subject: Potassium
subject: Energy
subject: Carbon nanotubes
subject: Doping
classificationCode: 539
subject: Moderne Physik

description: Single-walled carbon nanotubes (SWCNTs) can be doped with potassium, similar to graphite, leading to intercalation compounds. These binary systems exhibit a clear metallic character. However, the entire picture of how electron doping (e-doping) modifies the SWCNTs’ vibrational spectra as a function of their diameter, chirality, and metallicity is still elusive. Herein, we present a detailed study of the intercalation and solid state reduction of metallic and semiconducting enriched HiPco SWCNTs. We performed a combined experimental and theoretical study of the evolution of their Raman response with potassium exposure, focusing specifically on their radial breathing mode (RBM). We found the charge donated from the potassium atoms occupies antibonding π orbitals of the SWCNTs, weakening their C–C bonds, and reducing the RBM frequency. This RBM downshift with increasing doping level is quasi-linear with a steplike behavior when the Fermi level crosses a van Hove singularity for semiconducting species. Moreover, this weakening of the C–C bonds is greater with decreasing curvature, or increasing diameter. Overall, this suggests the RBM downshift with e-doping is proportional to both the SWCNT’s integrated density of states (DOS) ϱ(ε) and diameter d. We have provided a precise and complete description of the complex electron doping mechanism in SWCNTs up to a charge density of −18 me/C, far beyond that achievable by standard gate voltage studies, not being the highest doping possible, but high enough to track the effects of doping in SWCNTs based on their excitation energy, diameter, band gap energy, chiral angle, and metallicity. This work is highly relevant to tuning the electronic properties of SWCNTs for applications in nanoelectronics, plasmonics, and thermoelectricity.
Sexual behaviour and barriers to STI testing among youth in Northeastern BC
Creators: name: Goldenberg, Shira
Publisher: name: University of British Columbia
Year: 2008

description: Introduction: Oil/gas communities across Northeastern British Columbia are experiencing rapid in-migration of young, primarily male workers in response to an economic ‘boom’ in the oil/gas sectors. Accompanying the ‘boom’ has been a rise in rates of sexually transmitted infections (STIs) among young people, with Chlamydia rates among youth in the Northeast exceeding the provincial average by 22%. Previous research indicates that socio-cultural and structural determinants of youth sexual behaviour and access to STI testing are important for understanding youth sexual health disparities – and represent key targets for STI prevention efforts. No other research has explored STIs in this rapidly developing, under-resourced context. Therefore, objectives of this thesis were to: (1) Examine how socio-cultural and structural features related to the oil/gas ‘boom’ affect the sexual behaviour of young people in Fort St. John (FSJ), BC; (2) Gather the perspectives of youth and their service providers on the socio-cultural and structural barriers to STI testing in FSJ; (3) Develop recommendations to improve the accessibility of STI testing. Results: Participants identified 4 main ways in which the socio-cultural and structural conditions created by the ‘boom’ affect sexual behaviours, fuelling the spread of STIs in FSJ: mobility of oil/gas workers; binge partying; high levels of disposable income; and gendered power dynamics. As well, 5 key barriers to STI testing among youth were identified: limited opportunities for access; geographic inaccessibility; local social norms; limited information; and negative interactions with providers. Discussion: These data indicate that the conditions fostered by the ‘boom’ in FSJ exacerbate sexual health inequalities among young people. They can be more widely contextualized as an example of the unintended – but not unexpected – health and social implications of a resource-extraction ‘boom’, illustrating the fallacy of ‘development’ as representing uniformly positive ‘progress’. Recommended actions include STI prevention and testing service delivery models that incorporate a locally tailored public awareness campaign, outreach to oil/gas workers, condom distribution, expanded clinic hours and drop-in appointments, specialized training for health care providers, and intersectoral partnerships between public health, non-profit organizations, and industry. An ongoing knowledge translation internship has been undertaken to implement some of these recommendations.
Additional file 6: Figure S3 of Health system delay among patients with tuberculosis in Taiwan: 2003â  2010
Creators: name: Chien-Chou Chen
name: Chen-Yuan Chiang
name: Sung-Ching Pan
name: Jann-Yuan Wang
name: Hsien-Ho Lin
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Computational Biology

description: Sensitivity analysis of health system delay (HSD) according to different cut-off intervals between two respiratory-related visits. (PDF 168Â kb)
title: Long-Term Outdoor Testing of Perovskite Mini-Modules: Effects of FACl Additives
Creators: name: Paraskeva, Vasiliki
name: Hadjipanayi, Maria
name: Norton, Matthew
name: Aguirre, Aranzazu
name: Hadipour, Afshin
name: Song, Wenya
name: Fontanot, Tommaso
name: Christiansen, Silke H.
name: Ebner, Rita
name: Georghiou, George E.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: perovskites
subject: performance degradation
subject: halide additives
classificationCode: 530
subject: Physik

description: The outdoor performance monitoring of perovskite modules over 16 weeks is reported. Two different types of active perovskite layers were studied: one type contained formamidinium chloride (FACl) halide additives and the other contained no additives with the main purpose to investigate performance trends during the outdoor exposure of those type of devices. Long-term side-by-side outdoor testing of devices with and without halide additives was not implemented in the past and merits investigation in order to determine the impact of additives on perovskite performance and stability. Although the two types of modules displayed similar initial outdoor performance characteristics, their outdoor performance evolution differed. Different degradation rates between the modules with and without additives were obtained just after field installation. In particular, the modules with additives exhibited higher performance degradation under open-circuit loading conditions between current-voltage (IV) scans. Long-term monitoring of both modules recorded a reduction of the efficiency over the course of the day with subsequent recovery overnight and in many cases during the day. The relative values of performance degradation and overnight recovery were calculated over the timespan of outdoor testing and indicated dominant normalized diurnal performance degradation in one type of modules (without FACl additives) in the range between 15–20% and in the other type of modules (with additives) 5–10%. The dominant normalized performance recovery values found were 25–30% and 5–10%, respectively. Finally, dark lock-in thermography (DLIT) and Raman studies were performed on the exposed devices and revealed differences in hotspot evolution and vibrational modes between the different types of module.
Additional file 4: of The HAPPY (Healthy and Active Parenting Programmme for early Years) feasibility randomised control trial: acceptability and feasibility of an intervention to reduce infant obesity
Creators: name: McEachan, Rosemary
name: Santorelli, Gillian
name: Bryant, Maria
name: Pinki Sahota
name: Farrar, Diane
name: Small, Neil
name: Akhtar, Shaheen
name: Sargent, Judith
name: Barber, Sally
name: Taylor, Natalie
name: Richardson, Gerry
name: Farrin, Amanda
name: Bhopal, Raj
name: Bingham, Daniel
name: Ahern, Sara
name: Wright, John
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Details of accelerometry analysis. (PDF 309Â kb)
title: Surface structuring of β-TCP and transition to α-TCP induced by femtosecond laser processing
Creators: name: Aceti, D. M.
name: Filipov, E.
name: Sotelo, L.
name: Fontanot, T.
name: Christiansen, Silke H.
name: Lasgorceix, M.
name: Leriche, A.
name: Buchvarov, I.
name: Daskalova, A.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: femtosecond laser processing
subject: quantum electronics
subject: tricalcium phosphate
subject: bioresorbable implants
classificationCode: 530
subject: Physik

description: Tricalcium phosphate (Ca3(PO4)2, TCP), is one of the most studied and used as material for bioresorbable implants. The β phase has a slower dissolution dynamic and ensures mechanical support for a longer time in biological environment, while a faster release of ions characterize the α phase that trigger a stronger biological response. In this work a femtosecond laser system was used to process β-TCP pellets surface. The femtosecond laser processing results in surface morphology modification, by turning the flat mirror polished surface into a rough and opaque one. The morphological and phisycochemical characteristics of material surface were studied by means of SEM, AFM, Raman, XRD and contact angle measurement. The processed surface showed the formation of micro and nano roughness alongside, furthermore a partial phase transformation from β-TCP to α-TCP was detected. A significant improvement in surface wettability for three different liquids (i.e.water, ethylene glycol and diiodo-methane) is reported. This implies an increase in surface free energy as well. The combination of α and β phase, together with the increased roughness obtained by laser processing, could positively affect the cell adhesion and metabolic activity.
Additional file 1: of New anti-cancer chemicals Ertredin and its derivatives, regulate oxidative phosphorylation and glycolysis and suppress sphere formation in vitro and tumor growth in EGFRvIII-transformed cells
Creators: name: Atsumi, Sonoko
name: Nosaka, Chisato
name: Hayamitsu Adachi
name: Kimura, Tomoyuki
name: Kobayashi, Yoshihiko
name: Takada, Hisashi
name: Watanabe, Takumi
name: Shun-Ichi Ohba
name: Inoue, Hiroyuki
name: Kawada, Manabu
name: Shibasaki, Masakatsu
name: Masabumi Shibuya
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Organic synthesis methods. (DOCX 46 kb)
title: Influence of Initial Surface Roughness on LIPSS Formation and Its Consecutive Impact on Cell/Bacteria Attachment for TiAl6V4 Surfaces
Creators: name: Sotelo, Lamborghini
name: Fontanot, Tommaso
name: Vig, Sanjana
name: Herre, Patrick
name: Yousefi, Peyman
name: Fernandes, Maria Helena
name: Sarau, George
name: Leuchs, Gerd
name: Christiansen, Silke H.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: biocompatibility
subject: laser functionalization
subject: laser-induced periodic surface structures
subject: TiAl6V4
classificationCode: 530
subject: Physik

description: The influence of the initial surface roughness of TiAl6V4 samples on the orientation and periodicity of the resulting laser-induced periodic surface structures (LIPSS), as well as the surface wettability and chemistry is reported here. Before LIPSS fabrication, initial sample surface roughness is adjusted by variations of finial polishing steps with polishing grain sizes of 18.3, 8.4, 5, and 0.5 µm. A 3 × 3 irradiation matrix was defined and lasered on all samples by changing the laser power and distance between consecutive laser scans. The resulting structures were characterized by scanning electron microscopy (SEM), atomic force microscopy, Raman spectroscopy, and contact angle measurements. As a further step, three representative generated structures were chosen to explore their bone implant viability by resazurin assays, alkaline phosphatase activity, and direct SEM imaging of the induced cells (MG63) and bacteria (Escherichia coli and Staphylococcus aureus). Results show that initial surface roughness has big influence on the wettability of the resulting surface, as well as inducing small variations on the orientation of the generated LIPSS. Structures generated with a higher integrated fluence have also shown to enhance cell differentiation while reducing bacterial activity, making them a great candidate for improved bone implant compatibility and durability.
title: Induced degradation of SNAP-fusion proteins
Creators: name: Pol, Savina Abraham
name: Liljenberg, Sara
name: Barr, Jack
name: Simon, Gina
name: Wong-Dilworth, Luis
name: Paterson, Danielle L.
name: Berishvili, Vladimir P.
name: Bottanelli, Francesca
name: Kaschani, Farnusch
name: Kaiser, Markus
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: self-labeling protein tags
subject: targeted protein degradation
subject: gene tagging
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Self-labeling protein tags are an efficient means to visualize, manipulate, and isolate engineered fusion proteins with suitable chemical probes. The SNAP-tag, which covalently conjugates to benzyl–guanine and –chloropyrimidine derivatives is used extensively in fluorescence microscopy, given the availability of suitable SNAP-ligand-based probes. Here, we extend the applicability of the SNAP-tag to targeted protein degradation. We developed a set of SNAP PROteolysis TArgeting Chimeras (SNAP-PROTACs), which recruit the VHL or CRBN-ubiquitin E3 ligases to induce the degradation of SNAP-fusion proteins. Endogenous tagging enabled the visualization and the selective depletion of a SNAP-clathrin light chain fusion protein using SNAP-PROTACs. The addition of PROTACs to the SNAP-tag reagent toolbox facilitates the comprehensive analysis of protein function with a single gene tagging event.
MOESM2 of Performance and time to become negative after treatment of three malaria rapid diagnostic tests in low and high malaria transmission settings
Creators: name: Grandesso, Francesco
name: Nabasumba, Carolyn
name: Nyehangane, Dan
name: Anne-Laure Page
name: Bastard, Mathieu
name: Smet, Martin De
name: Yap Boum
name: Jean-FranĂ§Ois Etard
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Additional analysis of the time to become negative for the three malaria RDTs where patients experiencing recurrent parasitaemia were censored at the day when recurrent parasitaemia occurred.
title: Divergent temporal responses of native macroinvertebrate communities to biological invasions
Creators: name: Soto, Ismael
name: Macêdo, Rafael L.
name: Carneiro, Laís
name: Briski, Elizabeta
name: Kouba, Antonin
name: Cuthbert, Ross N.
name: Haubrock, Phillip J.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: ecosystem functionality
subject: freshwater ecosystems
subject: invasive species
subject: non-native species
subject: management strategies
subject: temporal dynamics
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Biological invasions pose a major threat to biodiversity, ecosystem functioning, and human well-being. Non-native species can have severe ecological impacts that are transformative, affecting ecosystems across both short-term and long-term timescales. However, few studies have determined the temporal dynamics of impact between these scales, impeding future predictions as invasion rates continue to rise. Our study uses a meta-analytical approach to dissect the changing taxonomic and functional impacts of biological invasions on native macroinvertebrate populations and communities in freshwater ecosystems across Europe, using a recently collated European long-term time series spanning several decades. Our findings reveal a complex temporal pattern: while initial stages of invasions (i.e. five years after the first record of non-native species) often exhibited benign impacts on macroinvertebrate abundance, richness, or functional diversity, the long-term (i.e. the period following the early invasion) effects became predominantly negative. This pattern was consistent between taxonomic and functional metrics for impacts at both the population and species level, with taxonomic metrics initially positively affected by invasions and functional metrics being more stable before also declining. These results suggest that even initially benign or positively perceived impacts could be eventually superseded by negative consequences. Therefore, understanding the magnitude of invasion effects increasingly requires long-term studies spanning several years or decades to offer insights into effective conservation strategies prioritising immediate and future biodiversity protection efforts. These findings also highlight the importance of integrating multiple taxonomic, functional and temporal components to inform adaptive management approaches to mitigate the negative effects of current and future biological invasions.
Canadian feminist women directors : using the canon for social change
Creators: name: Ferguson, Sarah Alexandra
Publisher: name: University of British Columbia
Year: 2008

description: This thesis explores how five Canadian women directors who define themselves as feminists have engaged with work from the traditional Western theatre canon. However, that world actually is created by the social expectations, cultural mores, and theatrical conventions of its time. Audiences have been indoctrinated to accept unquestioningly the value of these texts while the plays’ valorized status masks social constructs that are continually reinforced and surreptitiously naturalized through their repetition. At the crux of this thesis is the notion that while repetition is used as a tool for social instruction, it can also be used as a tool for social change. Therefore, I explore how the Canadian feminist women directors whom I have interviewed use the uniqueness of performance in different ways to challenge social structures within canonical texts. In the individual chapters, each director first shares her education, training, experience, and influences; then she articulates her own feminist perspective and discusses its impact on her career and work process; and finally she reflects on how she directed a text from the Western theatre canon and used the liminal space of performance to challenge the text’s embedded gender constructs. At the end of each chapter, I present the critical response I found for each production, including reviews, individual statements, and academic investigations, and assess the extent to which the director’s intent was understood by her audience and reviewers. In the final chapters, I examine each individual director’s interview responses in the context of the others’ and situate them within the spectrum of feminisms. In general, the directors used liminal space to expose gender as a construction and destabilize social expectations based on gender. However, what also emerged from these interviews is that while there is no broad consensus of what constitutes ‘feminist’ work, each director must temper her feminist perspectives if she wants access to the upper echelons of directing in Canada and the benefits that it entails.
MOESM2 of Convergence of soil microbial properties after plant colonization of an experimental plant diversity gradient
Creators: name: Steinauer, Katja
name: Jensen, Britta
name: Strecker, Tanja
name: Luca, Enrica
name: Scheu, Stefan
name: Eisenhauer, Nico
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Additional file 2: Figure S1. Plant colonization effects on plant cover and plant biomass. Mean values with confidence intervals of colonizing plant species after (a) two years and (b) five years. (c) Mean values with confidence intervals of plant cover [%] after two years and (d) plant biomass [gÂ mâ  2] after five years. In c) and d) circles display plant cover and biomass of resident plant species of weeded subplots, respectively, and open circles display plant cover and biomass with resident plant species plus colonizing plant species of non-weeded subplots, respectively.
Water-use efficiency and productivity in native Canadian populations of Populus trichocarpa and Populus balsamifera
Creators: name: Pointeau, Virginie M.
Publisher: name: University of British Columbia
Year: 2008

description: Afforestation and reforestation programs utilizing available fields for biofuel production, carbon sequestration, and other uses linked to climate change are looking to tree physiologists to identify species and genotypes best-suited to their purposes. The ideal poplar genotype for use in Canadian programs would be drought-resistant, cold-climate adapted, and fast-growing, thus requiring an understanding of links between a variety of physiological traits linked to growth and productivity. This study examined the basis for variations in water-use efficiency within four selected populations of Populus trichocarpa and Populus balsamifera (2 provenances each). Each species included both a northern and a southern provenance. Correlations between water-use efficiency, nitrogen-use efficiency, ¹³C/¹²C isotope ratio, stomatal conductance, and overall productivity were evaluated. Gas exchange variables measured included net photosynthesis, transpiration rate, stomatal conductance, and intercellular CO₂ content. Water-use efficiency and ¹³C content across all genotypes were highly correlated. Results suggested that variation in water-use efficiency was primarily related to variation in stomatal conductance across all genotypes. Whereas differences in net photosynthesis in this study were not significant between species, P. balsamifera did reveal a higher average stem volume overall. Although variation in stomatal conductance was the major determinant of differences in water-use efficiency, positive correlations were found between ¹³C isotope abundance and net photosynthesis in both P. balsamifera provenances. In this regard, results for the northern P. balsamifera provenance are the most consistent across all gas-exchange and growth trait correlations, in terms of meeting expectations for sink-driven water-use efficiency. The findings in this study suggest the possibility of identifying poplar genotypes with an absence of trade-off between water-use efficiency and nitrogen-use efficiency, notably among genotypes from the northern P. balsamifera provenance, near Gillam.
title: Expression of Mutated BRAFV595E Kinase in Canine Carcinomas - An Immunohistochemical Study
Creators: name: Bartel, Annika
name: Aupperle-Lellbach, Heike
name: Kehl, Alexandra
name: Weidle, Silvia
name: Aeschlimann, Leonore
name: Klopfleisch, Robert
name: Brot, Simone De
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: dog
subject: molecular profiling
subject: BRAF
subject: genetic
subject: immunohistochemistry
subject: ddPCR
classificationCode: 616
subject: Krankheiten

description: Molecular profiling of cancer is used to examine for specific mutations or proteins and is becoming increasingly important in oncology. An example of such a mutation is the altered BRAF gene and the resulting changed BRAF protein, which is already known to play a role in urinary bladder and prostatic carcinomas in dogs. We assumed that the mutant BRAFV595E protein should be considered in other canine carcinomas and tested 227 samples of 11 different carcinoma origins (anal sac (n = 23), intestine (n = 21), liver (n = 21), lungs (n = 19), mammary gland (n = 20), nasal cavity (n = 21), oral epithelium (n = 18), ovary (n = 20), prostate (n = 21), thyroid gland (n = 21), urinary bladder (n = 22)). We used immunohistochemistry with two different primary antibodies, each binding to the altered BRAF protein, and confirmed our results with droplet digital PCR (ddPCR). Among all the tested canine carcinomas, we found BRAF-mutated tumours in the prostate (16/21), the urinary bladder (17/22), and the oral cavity epithelium (4/18), while other carcinomas tested negative. Our findings showed that both antibodies are dependable tools for detecting the BRAFV595E mutation in canine carcinomas. Detecting BRAF mutations is important for applying future therapeutic approaches, including BRAF inhibitors.
MOESM3 of Convergence of soil microbial properties after plant colonization of an experimental plant diversity gradient
Creators: name: Steinauer, Katja
name: Jensen, Britta
name: Strecker, Tanja
name: Luca, Enrica
name: Scheu, Stefan
name: Eisenhauer, Nico
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology
subject: 60506 Virology

description: Additional file 3: Figure S2. Plant colonization effects on soil microbial properties. Mean values with confidence intervals of basal respiration [µg O2 g−1 soil dry mass h−1] (a) two and (c) five years, and soil microbial biomass [µg C g−1 soil dry mass] (b) two and (d) five years after colonization by plant species. Circles display basal respiration and soil microbial biomass with resident plant species of weeded subplots, respectively, and open circles display basal respiration and soil microbial biomass with resident plant species plus colonizing plant species of non-weeded subplots, respectively.
MOESM1 of A polysaccharide utilization locus from Flavobacterium johnsoniae enables conversion of recalcitrant chitin
Creators: name: Larsbrink, Johan
name: Yongtao Zhu
name: Sampada Kharade
name: Kwiatkowski, Kurt
name: Eijsink, Vincent
name: Koropatkin, Nicole
name: McBride, Mark
name: Pope, Phillip
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 1: Tables S1â  S3. Strains, plasmids and primers used in the study, Table S4. X-ray data and refinement statistics. Figure S1. Chitin utilization of wild type F. johnsoniae and mutants, Figure S2. Western blot immunodetection of ChiA, Figure S3. Growth curves of cells carrying pYT353 (CusCI) on chitin and glucose, Figure S4. Growth curves of wild type cells and predicted cytoplasmic inner membrane sugar transporter mutants, Figure S5. Binding analysis of the CusD proteins to insoluble polysaccharides, Figure S6. Section of a structural alignment of Serratia marcescens chitinases (ChiA, B and C) and the ChiUL chitinases, Figure S7. pH profiles of the ChiUL enzymes.
Monte-Carlo simulations of positron emission tomography based on liquid xenon detectors
Creators: name: Lu, Philip Fei-Tung
Publisher: name: University of British Columbia
Year: 2008

description: The prospects for enhanced Positron Emission Tomography imaging using liquid xenon (LXe) gamma ray detectors had been examined. Monte-Carlo simulations using GEANT4 were performed and the results were used to study the expected performance of a small animal PET scanner in comparison with a simulated conventional small animal scanner (LSO Focus 120). A NEMA-like cylinder phantom and an image contrast phantom were simulated with both scanners to compare performance characteristics. A Compton reconstruction algorithm was developed for the LXe scanner, and its performance and limitations studied.
Penerapan Metode Diskusi dalam Upaya Penanaman Pendidikan Karakter melalui Kesepakatan Kelas VI B UPTD SDN Kamal 2
Creators: name: Wahyu Nur Cahyani, Indah
name: Pratikno, Ahmad Sudi
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390304
subject: Primary education
classificationCode: 460105
subject: Applications in social sciences and education

description: Penelitian ini bertujuan untuk mengetahui bagaimana metode yang diterapkan sesuai dengan upaya penanaman karakter siswa melalui budaya positif di kelas. Penelitian ini menggunakan metode kualitatif dengan deskriptif dan analisis. Metode pengumpulan data yang digunakan meliputi observasi, wawancara dan dokumentasi. Metode diskusi merupakan metode pembelajaran yang di mana siswa berdialog satu sama lain atau dengan guru untuk membahas topik, masalah, atau studi kasus. Upaya penguatan pendidikan karakter di kelas dapat melibatkan siswa secara langsung dengan mendiskusikan kesepakatan kelas. Hal ini dapat menciptakan keinginan untuk bertanggung jawab atas perjanjian yang dibuat. Terlihat dari para siswa Kelas VI B UPTD SDN Kamal 2 antusias dan aktif dalam membuat kesepakatan kelas. Siswa secara penuh bertanggung jawab untuk mentaati perjanjian yang mereka buat dan melahirkan karakter yang baik dari diri siswa antara kejujuran, sopan, tanggung jawab, kedisiplinan dan mendengarkan guru saat menjelaskan pembelajaran sehingga kelas merasa lebih tenang saat belajar.
Additional file 1: of Is upper limb virtual reality training more intensive than conventional training for patients in the subacute phase after stroke? An analysis of treatment intensity and content
Creators: name: Brunner, Iris
name: Skouen, Jan
name: Hofstad, Håkon
name: Aßmuss, Jörg
name: Becker, Frank
name: Pallesen, Hanne
name: Thijs, Liselot
name: Verheyden, Geert
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: The scoring form. (PDF 145 kb)
Cavonus Sharp 1875
Creators: name: Hutchinson, Paul M.
name: Allsopp, Peter G.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dynastidae
Cavonus

description: Key to Cavonus females (modified from Carne 1957)
Females of C. leai and C. fovealacus are unknown.
1. Clypeus with sides sinuate.............................................................................. 2
- Clypeus evenly rounded................................................................................ 4
2. Clypeal apex bisinuate; dorsal elytral striae heavily impressed and continuous over apical calli...... C. acutifrons Lea, 1917
- Clypeal apex truncate; dorsal elytral striae obsolete posterior to apical calli....................................... 3
3. Posteromedian area of pronotum finely micropunctate, surface microreticulate; frons with a transverse groove behind clypeofrontal ridge (Carne 1957, Fig. 337)................................................... C. sharpi Blackburn, 1888
- Posteromedian area of pronotum with coarse punctation, surface shiny; frons lacking, or with only a trace of a transverse groove............................................................................ C. armatus Sharp, 1875
4. Coxal vestiture brownish black; metatibia with smaller spur straight, blunt; scutellum punctate at base but without submarginal sculpturing..................................................................... C. niger (Blackburn, 1888)
- Coxal vestiture dark brown or brownish yellow; metatibia with smaller spur strongly curved, subacute; scutellum with welldefined submarginal groove or punctures.................................................................. 5
5. Coxal vestiture brownish yellow; pronotum lacking anteromedial swelling, surface strongly convex; pygidium contracted either side of apex, disc with impunctate median stripe................................... C. bidens (Blackburn, 1896)
- Coxal vestiture dark brown (Fig. 12); pronotum (Figs. 11, 14) with anteromedial swelling, surface slightly flattened behind swelling; pygidium (Fig. 16) not contracted on either side of apex, disc lacking impunctate median stripe.......................................................................................... C. sculpturatus Blackburn, 1888
description: Published as part of Hutchinson, Paul M. & Allsopp, Peter G., 2020, Cavonus Sharp, 1875 (Coleoptera: Scarabaeidae: Dynastinae: Pentodontini Pseudoryctina) in Western Australia with description of a new species and the female of Cavonus sculpturatus Blackburn, 1888, pp. 449-460 in Zootaxa 4852 (4) on page 459, DOI: 10.11646/zootaxa.4852.4.3, http://zenodo.org/record/4410079