cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Nucleotide sequence encoding the carboxyl-terminal half of apolipoprotein B from spontaneously hypercholesterolemic pigs.
Creators: name: Aiello, R J
name: Nevin, D N
name: Purtell, C
name: Sturley, S L
name: Kodoyianni, V
name: Kaiser, M
name: Ebert, D L
name: Grunwald, K
name: Lund-Katz, S
name: Maeda, N
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Previous studies from this laboratory characterized the hypercholesterolemia of pigs with a mutant allele of apolipoprotein B (apoB), designated Lpb5. This apoB allele is associated with low density lipoprotein (LDL) particles deficient in binding to the LDL receptor. To identify potential causative mutations in Lpb5 DNA, 10.6 kb of genomic DNA, encoding the carboxyl-terminal 58% of apoB were sequenced from the Lpb5 allele and from an allele encoding phenotypically normal apoB. Comparison of the two DNA sequences revealed 33 polymorphisms, 13 of which resulted in amino acid polymorphisms. To determine whether any of the amino acids at the polymorphic positions in Lpb5-encoded apoB were unique to that isoform, those positions were sequenced in four other pig apoB alleles encoding phenotypically normal apoB. None of the amino acids were by themselves uniquely encoded by the Lpb5 allele. However, a unique haplotype consisting of Asp3164 in conjunction with Ala3447 distinguished the Lpb5-encoded apoB from all other allelic isoforms sequenced in this region. To gain insight into changes in the tertiary structure of the mutant apoB, 13C-NMR analysis of LDL reductively methylated with [13C]-formaldehyde was performed. LDL has lysine residues that titrate at pH 10.5 and others that titrate at pH 8.9. The latter residues are thought to include those involved in the interaction of LDL with the LDL receptor. LDL from Lpb5 pigs possessed a smaller proportion of lysine residues titrating at pH 8.9 than did LDL from non-Lpb5 pigs, suggesting that the Lpb5-encoded apoB is altered in a manner affecting the microenvironment of particular lysine residues.
Decays of the Lightest Top Squark
Creators: name: Boehm, C.
name: Djouadi, A.
name: Mambrini, Y.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We analyze higher order decay modes of the lightest top squark $\tilde{t}_1$ in the Minimal Supersymmetric extension of the Standard Model (MSSM), where the lightest SUSY particle (LSP) is assumed to be the neutralino $χ_1^0$. For small $\tilde{t}_1$ masses accessible at LEP2 and the Tevatron, we show that the four-body decay mode into the LSP, a bottom quark and two massless fermions, $\tilde{t}_1 \ra b χ_1^0 f\bar{f}'$, can dominate in a wide range of the MSSM parameter space over the loop-induced decay into a charm quark and the LSP, $\tilde{t}_1 \ra c χ_1^0$. This result might affect the experimental searches on this particle, since only the later signal has been considered so far.
description: 21 pages with 4 figures, Latex. Typo corrected and references updated. To appear in Phys. Rev. D
Pheidole jivaro Wilson, 2003, new species
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole jivaro

description: Pheidole jivaro new species
Types Mus. Comp. Zool. Harvard.
Etymology Named after the celebrated indigenous Amerindian tribe.
Diagnosis Similar to other members of the " carapuna complex," listed above.
Major: a low, long convexity emerges from the midclypeus, as illustrated; pilosity long, with a few hairs on mesosomal dorsum over 1.5X Eye Length; mesonotal convexity very low, giving promesonotum in side view a newly smooth semicircular profile, postpetiole from above oval; almost all of posterior third of head smooth and shiny; anterior fringe of pronotum carinulate and most of mesopleuron foveolate.
Minor: occiput narrowed, with nuchal collar; pilosity long, with some hairs on dorsum of head greater than Eye Length. Measurements (mm) Holotype major: HW 1.06, HL 1.20, SL 0.60, EL 0.14, PW 0.54. Paratype minor: HW 0.54, HL 0.70, SL 0.84, EL 0.14, PW 0.38.
Color Major: body and mandibles brownish yellow, other appendages plain dark yellow.
Minor: head and mesosoma dark brown; waist and gaster light to medium brown; mandibles and tarsi yellow; other appendages brownish yellow.
Range Known from the type locality and from Cerro Campana, Panama, 950 m (A. Newton).
Biology The Cerro Campana series was collected from leaf litter on the floor of rainforest. A winged queen was collected with the type colony on 29 June 1976.
figure Upper: holotype, major. Lower: paratype, minor. ECUADOR: Misahualli, Napo (C. Tarrant). Scale bars = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 713
Quasielastic K+ scattering in nuclei
Creators: name: De Pace, A.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The quasielastic scattering kaon-nucleus experiment performed at BNL is analyzed in a finite nucleus continuum random phase approximation framework, treating the reaction mechanism in Glauber theory up to two-step inelastic processes. A good description of the data is achieved, also providing a useful constraint on the strength of the effective particle-hole interaction in the scalar-isoscalar channel at intermediate momentum transfers.
description: 4 pages, 3 figures, needs espcrc1 and epsfig; presented at the International Conference on Hypernuclear and Strange Particle Physics, BNL October 13-18, 1997
IMPLEMENTAÇÃO DE UM SISTEMA DE CONTROLE DE ACESSO UTILIZANDO AWS REKOGNITION
Creators: name: Firmino, Marcelo Alves de Oliveira Firmino Junior
name: Ramos, Guilherme dos Santos Ramos
Publisher: name: Zenodo
Year: 2024
Subjects: AWS Rekognition
Reconhecimento facial
Controle de acesso

description: O aumento das ameaças vulnerabilidades em ambientes restritos, o controle de acesso seguro se tornou uma necessidade crescente. A tecnologia de reconhecimento facial surge como uma solução promissora para atender essa demanda, sendo uma das mais eficazes no controle de acesso. Este estudo visa analisar a precisão e segurança de um sistema de controle de acesso baseado na API AWS Rekognition, avaliando seu desempenho em diferentes ambientes e condições, como variações de iluminação e ângulo de capturas.
Topological mechanics in quasicrystals
Creators: name: Zhou, Di
name: Zhang, Leyou
name: Mao, Xiaoming
Publisher: name: arXiv
Year: 2018
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study topological mechanics in two-dimensional quasicrystalline parallelogram tilings. Topological mechanics has been studied intensively in periodic lattices in the past a few years, leading to the discovery of topologically protected boundary floppy modes in Maxwell lattices. In this paper we extend this concept to quasicrystalline parallelogram tillings and we use the Penrose tiling as our example to demonstrate how these topological boundary floppy modes arise with a small geometric perturbation to the tiling. The same construction can also be applied to disordered parallelogram tilings to generate topological boundary floppy modes. We prove the existence of these topological boundary floppy modes using a duality theorem which relates floppy modes and states of self stress in parallelogram tilings and fiber networks, which are Maxwell reciprocal diagrams to one another. We find that, due to the unusual rotational symmetry of quasicrystals, the resulting topological polarization can exhibit orientations not allowed in periodic lattices. Our result reveals new physics about the interplay between topological states and quasicrystalline order, and leads to novel designs of quasicrystalline topological mechanical metamaterials.
description: 16 pages, 8 figures
stPipe - a comprehensive tool facilitating spatial transcriptomics benchmarking
Creators: name: Xu, Yang
name: Ritchie, Matthew
Publisher: name: Zenodo
Year: 2025
Subjects: Spatial transcriptomics

description: The stPipe package provides a comprehensive pipeline for preprocessing sequencing-based spatial transcriptomics data, including 10X Visium, BGI Stereo-seq, Slide-seq, and Curio-seeker.
Thermal noise in superconducting quantum point-contacts
Creators: name: Martin-Rodero, A.
name: Yeyati, A. Levy
name: Garcia-Vidal, F. J.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We present a theory for the frequency-dependent current fluctuations in superconducting quantum point-contacts (SQPC) within the dc transport regime. This theory is valid for any barrier transparency between the tunnel and ballistic limits, yielding an analytical expression for the fluctuations spectrum in the subgap region. It is shown that the level of noise in a quasi-ballistic SQPC may have a huge increase in comparison with the case of a normal contact carrying the same average current. The effect of this high level of noise on the actual observability of the current-phase relation for a ballistic point-contact is discussed in connection with recent experimental measurements.
description: 11 pages, REVTEX, including 2 Postscript figures
Pheidole laeviventris
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole laeviventris

description: Pheidole laeviventris Mayr
Pheidole laeviventris Mayr 1870a: 401.
Types Naturhist. Mus. Wien.
etymology L laeviventris, smooth belly, referring to gaster.
diagnosis Similar to aper, bambusarum, brevicona, dyctiota, lutzi, risii, rugatula, senilis, sigillata, trachyderma, and traini, distinguished as follows. Major: unknown.
Minor: occiput and sides of head rugoreticulate; vertex, antennal fossae, and frontal lobes carinulate; frontal triangle and midclypeus smooth; anterior and posterior thirds of pronotum foveolate, center smooth; occiput narrow, lacking nuchal collar or with rudiment only; humerus subangulate; propodeal spine equilaterally triangular.
Measurements (mm) Lectotype minor: HW 0.66, HL 0.78, SL 0.82, EL 0.14, PW 0.40.
color Minor: body concolorous medium reddish brown, appendages brownish yellow.
range Known only from the type locality (Colombia, no further data).
Biology Unknown.
Figure Lectotype, minor. COLOMBIA (no further data). Major: unknown. Scale bar = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 714
Full model details from The role of familiarity in signaller–receiver interactions
Creators: name: Ma, Wei Ji
name: Higham, James P.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: In animal communication, individuals of species exhibiting individual recognition of conspecifics with whom they have repeated interactions, receive signals not only from unfamiliar conspecifics, but also from individuals with whom they have prior experience. Empirical evidence suggests that familiarity with a specific signaller aids receivers in interpreting that signaller's signals, but there has been little theoretical work on this effect. Here, we develop a Bayesian decision-making model and apply it to the well-studied systems of primate ovulation signals. We compare the siring probability of learner males versus non-learner males, based on variation in their assessment of the best time to mate and mate-guard females. We compare males of different dominance ranks, and vary the number of females, and their cycle synchrony. We find strong fitness advantages for learners, which manifest very quickly. Receivers do not have to see the full range of a signaller's signals in order to start gaining familiarity benefits. Reproductive asynchrony and increasing the number of females both enhance learning advantages. We provide theoretical evidence for a strong advantage to specific learning of a signaller's range of signals in signalling systems. Our results have broad implications, not only for understanding communication, but in elucidating additional fitness benefits to group-living, the evolution of individual recognition, and other characteristics of animal behavioural biology.
Effect of apolipoprotein A-I deficiency on lecithin:cholesterol acyltransferase activation in mouse plasma
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: Plasma cholesteryl ester (CE) synthesis by lecithin cholesterol acyltransferase (LCAT) is activated by apolipoprotein (apo)A-I. We studied the effect of plasma apoA-I concentration on LCAT activation, using normal, heterozygous or homozygous apoA-I-deficient mice made by gene targeting. Plasma esterified cholesterol concentrations of mice fed chow diets were ordered (mean +/- SEM): 105 +/- 7 (normal) > 70 +/- 5 (heterozygotes) > 26 +/- 2 (homozygotes) mg/dl. Plasma free cholesterol concentrations were similar among the three genotypes. Endogenous LCAT activity, measured as the decrease in plasma free cholesterol after a 1 h incubation at 37 degrees C, was ordered: 44 +/- 3 (normal) > 21 +/- 2 (heterozygotes) > 5 +/- 1 (homozygotes) nmol CE formed/h per ml plasma. Using a recombinant exogenous substrate consisting of egg yolk phospholipid, [14C]cholesterol, and apoA-I, CE formation of normals and heterozygotes was similar (27.4 +/- 0.6 and 28.8 +/- 1.3 nmol/h per ml plasma, respectively), but was significantly less for homozygotes (19.2 +/- 1.7 nmol/h per ml plasma). However, using a small unilamellar vesicle substrate particle containing phospholipid and [14C]cholesterol, CE formation was ordered: 1.6 +/- 0.1 (normal) = 1.6 +/- 0.1 (heterozygotes) > 0.6 +/- 0.1 (homozygotes) nmol/h per ml plasma; addition of apoA-I to the plasma of homozygous animals restored CE formation to normal levels (1.6 +/- 0.1). CE fatty acid analysis demonstrated that plasma from homozygous mice contained significantly more saturated and monounsaturated and fewer polyunsaturated fatty acids compared to normal and heterozygous mice.( TRUNCATED AT 250 WORDS)
Supplemental data_ Endothelial glycocalyx regulates cytoadherence in Plasmodium falciparum malaria
Creators: name: Introini, Viola
name: Carciati, Antonio
name: Tomaiuolo, Giovanna
name: Cicuta, Pietro
name: Guido, Stefano
Publisher: name: The Royal Society
Year: 2018
Subjects: Biophysics
Biotechnology
Biological Engineering

description: Malaria is associated with significant microcirculation disorders, especially when the infection reaches its severe stage. This can lead to a range of fatal conditions, from cerebral malaria to multiple organ failure, of not fully understood pathogenesis. It has recently been proposed that a breakdown of the glycocalyx, the carbohydrate-rich layer lining the vascular endothelium, plays a key role in severe malaria (SM), but direct evidence supporting this hypothesis is still lacking. Here, the interactions between Plasmodium falciparum infected red blood cells (PfRBCs) and endothelial glycocalyx are investigated by developing an in vitro, physiologically relevant model of human microcirculation based on microfluidics. Impairment of the glycocalyx is obtained by enzymatic removal of sialic acids residues, which, due to their terminal location and net negative charge, are implicated in the initial interactions with contacting cells. We show a more than twofold increase of PfRBCs adhesion to endothelial cells upon enzymatic treatment, relative to untreated endothelial cells. As a control, no effect of enzymatic treatment on healthy red blood cells adhesion is found. The increased adhesion of PfRBCs is also associated with cell flipping and reduced velocity as compared to the untreated endothelium. Altogether, these results provide a compelling evidence of the increased cytoadherence of PfRBCs to glycocalyx-impaired vascular endothelium, thus supporting the advocated role of glycocalyx disruption in the pathogenesis of this disease.
Microwave background anisotropies in quasiopen inflation
Creators: name: Garcia-Bellido, Juan
name: Garriga, Jaume
name: Montes, Xavier
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Quasiopenness seems to be generic to multi-field models of single-bubble open inflation. Instead of producing infinite open universes, these models actually produce an ensemble of very large but finite inflating islands. In this paper we study the possible constraints from CMB anisotropies on existing models of open inflation. The effect of supercurvature anisotropies combined with the quasiopenness of the inflating regions make some models incompatible with observations, and severely reduces the parameter space of others. Supernatural open inflation and the uncoupled two-field model seem to be ruled out due to these constraints for values of $Ω_0\lesssim0.98$. Others, such as the open hybrid inflation model with suitable parameters for the slow roll potential can be made compatible with observations.
description: 19 pages, ReVTeX, 10 figures inserted with epsf
Pheidole laudatana Wilson, 2003, new species
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole laudatana

description: Pheidole laudatana new species
Types Mus. Comp. Zool. Harvard.
Etymology Name based on the type locality.
Diagnosis A member of the tristis group, and in particular the complex of West Indian species that include alayoi, bakeri, macromischoides, and naylae of Cuba, hispaniolae of the Dominican Republic, and godmani of St. Vincent, as well as their close relatives sabina of Mexico and prattorum of Costa Rica. Distinguished in the major and minor workers by a unique combination of traits in shape and sculpturing, especially in the head and mesonotum, size of the propodeal spine, overall pilosity, and other characters as shown.
measurements (mm) Holotype major: HW 1.12, HL 1.18, SL 0.72,. EL 0.12, PW 0.58.
Paratype minor: HW 0.58, HL 0.64, SL 0.64, EL 0.12, PW 0.34.
Color Major: body and mandibles light brown, other appendages yellow.
Minor: body light yellowish brown, mandibles and other appendages medium yellow.
Range Known only from the type locality in montane Dominica.
Biology The type series was collected in elfin forest.
Figure Upper: holotype, major. Lower: paratype, minor. DOMINICA, WEST INDIES: Morne Macaque, elfin forest on road to Fresh Water Lake, 1.5 km east of Laudat, about 800 m (M. E. and P. D. Perkins). Scale bars = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 715
In vivo cholesterol kinetics in apolipoprotein E-deficient and control mice.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: The in vivo total body cholesterol transport of homozygous apoE-deficient (-/-) and control (+/+) mice was evaluated by compartmental analysis of plasma cholesterol decay. Body cholesterol fractional catabolic rates of chow fed mutants were less (-/-, 0.17 +/- 0.02; +/+, 0.51 +/- 0.06 day-1) and body cholesterol contents greater (-/-, 68 +/- 5; +/+, 48 +/- 5 mumol) than controls. The body cholesterol expansion of the chow-fed mutant was extracellular with at least half in plasma. Cholesterol transport, i.e., the mass entering, moving through, and exiting the body each day, was similar (-/-, 6.9 +/- 0.7; +/+, 8.5 +/- 0.9 mumol/day) for homozygotes and controls on chow, and both tripled with cholesterol feeding. Differing from controls, however, mutants had considerable expansions of plasma and body cholesterol (-/-, 166 +/- 21; +/+, 59 +/- 11 mumol) with increments in peripheral tissue cholesterol contents. Cholesterol feeding increased control hepatic cholesterol without a change in plasma, whereas mutants had large increments in plasma cholesterol with no change in liver. Consistent with impaired hepatic uptake of cholesterol, mutants had much slower plasma clearance of lipoprotein cholesterol, as well as slower transfer to catabolic pools than normals. Treatment of homozygotes with lovastatin doubled both plasma cholesterol concentration and body cholesterol transport indicating the importance of apoE-dependent cell cholesterol transfer in synthetic down-regulation with this agent. These data indicate that mice lacking apoE have lower affinity hepatic uptake of plasma remnant cholesterol.(ABSTRACT TRUNCATED AT 250 WORDS)
An Academic's Observations from a Sabbatical at Google
Creators: name: Barker, Adam
Publisher: name: arXiv
Year: 2018
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: How experiences gained in industry can improve academic research and teaching.
description: Preprint which appears in Communications of the ACM, August 2018, Vol. 61 No. 9, Pages 31-33
title: Thermal analysis of combined Organic Rankine-Vapour compression system for heating and cooling applications
Creators: name: Al-Tameemi, Mohammed Ridha Jawad
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Combined heat pump and ORC cycles, heat recovery, dynamic modeling, heat pump water heater, domestic hot water, data center cooling with central heating, diesel engine waste heat recovery for refrigeration.

description: Climate change due to global warming is a matter of major global concern. Greenhouse gases emissions are a key culprit in this process. It is therefore important to reduce energy consumption in order to protect the environment. The decarbonisation of the heating sector would have a significant positive impact on the environment. A wide range of heating technologies have been investigated and developed, such as gas boilers, electric restrictive heaters, heat pumps (HP), and others. In order to reduce fossil fuel consumption and greenhouse gas emissions, researchers have focused on improving the performance of the existing technologies as well as on developing new fuel-efficient systems such as cogeneration and trigeneration cycles. These integrated technologies allow the production of multi-mode energies including heating, cooling, and/or mechanical power from the same primary energy source. The energy source can be a fossil fuel, or renewable energy such as solar, geothermal, biomass or wasted heat. Waste heat utilization (from a data centre, internal combustion engine, chamber exhaust stream, etc.) also has the potential of enhancing the system performance by reducing fuel consumption. In this thesis, an innovative gas fuelled heating system based on a combined heat engine and its reverse heat pump cycle is proposed and investigated. This system consists of a gas burner, an organic Rankine cycle power generator, and an air source heat pump vapour compression cycle. For the theoretical analysis, in-house MATLAB code is developed, and the steady state results are compared with the results acquired from ASPEN PLUS as a benchmark. Both software programs use REFPROP as the database for working fluid thermophysical properties. In order to identify a suitable working fluid for each cycle, a comparative study on various working fluids was initially carried out. The selection of refrigerant was based on performance and environmental safety profile. The proposed cycle is designed for domestic hot water supply and utilizes gas burner flue gases and ambient air to enhance the system overall fuel to heat efficiency while maintaining the heat pump cycle in a frost free state at low ambient temperature. The combined cycle shows promising performance, with a fuel to heat efficiency of 136%. However, the results also show that ambient air temperature fluctuations can have a significant impact on the combined system’s performance. To tackle this, various control strategies are proposed and investigated. Also, a dynamic model has been built using ASPEN PLUS software to simulate and validate the control strategy.
Maize and Pigeon Pea Production, Profitability, and Tied Credit in Southern Shan State
Creators: name: Peixun Fang
name: Belton, Ben
name: Peixun Fang
name: Belton, Ben
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Food Security and Poverty
subject: Agrifood System Transformation
subject: Household Income and Livelihoods
subject: Input Use and Market Development
subject: Myanmar

description: This report presents results from by far the most comprehensive survey of maize cultivators ever conducted in Myanmar. This research was designed to test characterizations of hybrid maize farming in the literature on Myanmar empirically, and identify implications for development policy and programming. A study by the World Bank (2016) suggests that returns from maize farming are very high in comparison to other major crops grown in Myanmar, whereas two studies by Woods (2015a; 2015b) list a host of negative impacts associated with hybrid maize cultivation, including reduced food security, widespread and severe indebtedness among the smallest farmers, and deepening inequality. Our survey represented the population of all maize growing village tracts in the nine major maize growing townships of southern Shan where the security situation at the time of the survey permitted access. A total 884 maize growing and 678 non-maize growing rural households were interviewed. We summarize key survey results and their implications below.
Metabolism of fenbufen by cultured 3T3-L1 adipocytes: synthesis and metabolism of xenobiotic glycerolipids.
Creators: name: Ranasinghe, A
name: Dodds, P F
name: Chou, S C
name: Coleman, R A
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: The storage of xenobiotic compounds as glycerolipids and their subsequent mobilization was studied using fenbufen and differentiated 3T3-L1 cells in culture. Fenbufen was taken up from the incubation medium and incorporated into triacylglycerol, diacylglycerol, and phospholipids. The triacylglycerol was susceptible to digestion by pancreatic lipase. The xenobiotic phospholipid contained three species, one of which behaved as fenbufenoyl phosphatidylcholine as judged by TLC, HPLC, choline analysis, and mass spectroscopy. After incubation with radioactive fenbufen for 18 h, the cells were transferred to a chase medium where radioactivity was lost from the cells and appeared in the medium. The rate was three times higher when 10 microM isoproterenol was present; insulin had no effect. Non-esterified fenbufen and analogues of mono- and di-acylglycerol were secreted. Monofenbufenoylglycerol was characterized by its ability to be used as a substrate by purified monoacylglycerol acyltransferase. When oleic acid was used in place of fenbufen, the majority of the radioactivity released in a chase experiment was the non-esterified acid (over 90%) and neither mono- nor di-acylglycerol was detected. These data indicate that 3T3-L1 adipocytes can synthesize fenbufen-containing lipids and release them into the medium on hormonal stimulation. The secretion of mono- and di-acylglycerols may have unforeseen pharmacological or toxicological implications.
Raman evidence for dimerization and Mott collapse in $α$-RuCl$_3$ under pressures
Creators: name: Li, Gaomin
name: Chen, Xiaobin
name: Gan, Yuan
name: Li, Fenglei
name: Yan, Mingqi
name: Pei, Shenghai
name: Zhang, Yujun
name: Wang, Le
name: Su, Huimin
name: Dai, Junfeng
name: Chen, Yuanzhen
name: Shi, Youguo
name: Wang, XinWei
name: Zhang, Liyuan
name: Wang, Shanmin
name: Yu, Dapeng
name: Ye, Fei
name: Mei, Jia-Wei
name: Huang, Mingyuan
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We perform Raman spectroscopy studies on $α$-RuCl$_3$ at room temperature to explore its phase transitions of magnetism and chemical bonding under pressures. The Raman measurements resolve two critical pressures, about $p_1=1.1$~GPa and $p_2=1.7$~GPa, involving very different intertwining behaviors between the structural and magnetic excitations. With increasing pressures, a stacking order phase transition of $α$-RuCl$_3$ layers develops at $p_1=1.1$~GPa, indicated by the new Raman phonon modes and the modest Raman magnetic susceptibility adjustment. The abnormal softening and splitting of the Ru in-plane Raman mode provide direct evidence of the in-plane dimerization of the Ru-Ru bonds at $p_2=1.7$~GPa. The Raman susceptibility is greatly enhanced with pressure increasing and sharply suppressed after the dimerization. We propose that the system undergoes Mott collapse at $p_2=1.7$~GPa and turns into a dimerized correlated band insulator. Our studies demonstrate competitions between Kitaev physics, magnetism, and chemical bondings in Kitaev compounds.
description: 7 pages, 4 figures
Multiplicity of (Mini-)Jets at Small x
Creators: name: Ewerz, Carlo
name: Webber, Bryan R.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We derive closed expressions for the mean and variance of the (mini-)jet multiplicity distribution in hard scattering processes at low x. Here (mini-)jets are defined as those due to initial-state radiation of gluons with transverse momenta greater than some resolution scale m_R, where Lambda^2 << m_R^2 << Q^2, Lambda being the intrinsic QCD scale and Q the momentum transfer scale of the hard scattering. Our results are valid to leading order in log(1/x) but include all sub-leading logarithms of Q^2/m_R^2. As an illustration, we predict the mini-jet multiplicity in Higgs boson production at the Large Hadron Collider.
description: 14 pages, 5 figures
Modeling Thermal Fluctuations: Phase Mixing and Percolation
Creators: name: Gleiser, Marcelo
name: Heckler, Andrew F.
name: Kolb, Edward W.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Condensed Matter (cond-mat)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the nonequilibrium dynamics of a a real scalar field in a degenerate double-well potential. The system is prepared in the lowest free energy state in one of the wells and the dynamics is driven by the coupling of the field to a thermal bath. Using a simple analytical model, based on the subcritical bubbles method, we compute the fraction of the total volume which fluctuates to the opposite phase as a function of the parameters of the potential. Furthermore, we show how complete phase mixing, {\em i.e.} symmetry restoration, is related to percolation, which is dynamically driven by domain instability. Our method describes quantitatively recent results obtained by numerical simulations, and is applicable to systems in the Ising universality class.
description: Latex, 7 pages, 2 postscript figures, submitted to PRL. Also available at http://fnas08.fnal.gov/
Pheidole lutzi
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole lutzi

description: Pheidole lutzi Forel
Pheidole lutzi Forel 1905e: 168. Syn.: Pheidole lutzi var. heinzi Forel 1913m: 225, n. syn.
Types Mus. Hist. Nat. Geneve.
Etymology Named after the collector, Adolpho Lutz.
diagnosis Similar in various traits to aper, bambusarum, brevicona, dyctiota, laeviventris, risii, rugatula, senilis, sigillata, trachyderma, and traini, differing as follows.
Major: head from the side and in full-face view subrectangular, elongate (Head Length 1.2X Head Width), expanded slightly anterior to eyes so that in full-face view the anterior margin is wider than the occiput; all of dorsal head surface, including frontal lobes rugoreticulate (except for antennal fossae, which are rugulose, and frontal triangle and midclypeus, which are smooth); all of promesothorax rugoreticulate; propodeal spines thin, one-third as long as propodeal basal face; postpetiole from above diamond-shaped.
Minor: most of dorsal head surface and all of promesothorax rugoreticulate; occiput strongly narrowed but with no nuchal collar; in side view propodeum descends to metanotum in vertical face.
Measurements (mm) Lectotype major: HW 1.26, HL 1.54, SL 0.80,. EL 0.20, PW 0.74. Paralectotype minor: HW 0.70, HL 0.84, SL 0.84, EL 0.12, PW 0.48.
Color Major: head, mesosoma, and antennae medium reddish brown; waist, gaster, and legs light reddish brown. Minor: concolorous light reddish brown.
Range Known only from the type locality.
Biology The types were collected from a cavity in a bamboo trunk.
figure Upper: lectotype, major. Lower: paralectotype, minor. BRAZIL: Serra da Cantareira, Sao Paulo (Adolpho Lutz). Scale bars = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 716
Bayesian model-based spatiotemporal survey design for log-Gaussian Cox process
Creators: name: Liu, Jia
name: Vanhatalo, Jarno
Publisher: name: arXiv
Year: 2018
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: In geostatistics, the design for data collection is central for accurate prediction and parameter inference. One important class of geostatistical models is log-Gaussian Cox process (LGCP) which is used extensively, for example, in ecology. However, there are no formal analyses on optimal designs for LGCP models. In this work, we develop a novel model-based experimental design for LGCP modeling of spatiotemporal point process data. We propose a new spatially balanced rejection sampling design which directs sampling to spatiotemporal locations that are a priori expected to provide most information. We compare the rejection sampling design to traditional balanced and uniform random designs using the average predictive variance loss function and the Kullback-Leibler divergence between prior and posterior for the LGCP intensity function. Our results show that the rejection sampling method outperforms the corresponding balanced and uniform random sampling designs for LGCP whereas the latter work better for models with Gaussian models. We perform a case study applying our new sampling design to plan a survey for species distribution modeling on larval areas of two commercially important fish stocks on Finnish coastal areas. The case study results show that rejection sampling designs give considerable benefit compared to traditional designs. Results show also that best performing designs may vary considerably between target species.
Multifaktorielle Echtzeitdiagnose des Nutzerzustands in adaptiver Mensch-Maschine-Interaktion
Creators: name: Schwarz, Jessica Carolin
Publisher: name: Technische Universität Dortmund
Year: 2019
Subjects: subject: Erfassung mentaler Zustände
subject: Adaptive Mensch-Maschine-Systeme
subject: 150
subject: Mensch-Maschine-Interaktion
subject: Mensch-Maschine-System
subject: Mentaler Zustand
subject: Adaptives System

description: Konzepte adaptiver Systemgestaltung zielen darauf ab, den Operateur zustands- und situationsabhängig zu unterstützen, um Leistungsausfällen und -minderungen frühzeitig entgegenzuwirken und die Gesamtleistung des Mensch-Maschine-Systems zu optimieren. Gegenstand dieser Dissertation ist die Entwicklung einer Echtzeitdiagnose des Nutzerzustands, die Problemzustände und mögliche Ursachen während der Aufgabenbearbeitung erkennt und damit eine dynamische zustandsabhängige Auswahl und Anwendung von Adaptierungsstrategien ermöglicht. Auf Grundlage theoriebasierter und empirischer Erkenntnisse wurde mit RASMUS (Real-Time Assessment of Multidimensional User State) ein generisches Diagnosekonzept für eine ganzheitliche Erfassung und Bewertung des Nutzerzustands entwickelt. Im Unterschied zu anderen Forschungsarbeiten wird der Nutzerzustand hierbei multidimensional als Zusammenwirken von sechs mentalen Konstrukten definiert, die nachweislich die menschliche Leistungsfähigkeit beeinflussen können: Mentale Beanspruchung, Müdigkeit, Motivation, Aufmerksamkeit, Situationsbewusstsein sowie der emotionale Zustand. Die Erfassung dieser Zustände erfolgt multifaktoriell durch Kombination von physiologischen und verhaltensbasierten Maßen mit umwelt- und nutzerinternen Einflussfaktoren. Das Diagnosekonzept sieht vor, Adaptierungsbedarf auf Basis von Leistungsmaßen zu bestimmen. Auf diese Weise wird sichergestellt, dass die Adaptierung produktiven Selbstregulierungsstrategien des Nutzers nicht entgegenwirkt, die sich in Veränderungen des Nutzerzustands äußern können. Die multifaktorielle Bewertung des Nutzerzustands ermöglicht es im Weiteren, mögliche Ursachen für Leistungsverschlechterungen zu identifizieren, denen durch Auswahl und Anwendung geeigneter Adaptierungsstrategien entgegengewirkt werden kann. RASMUS wurde exemplarisch für den Anwendungsbereich der Luftraumüberwachung und drei ausgewählte Problemzustände (hohe Beanspruchung, passive aufgabenbezogene Müdigkeit sowie eine falsche Aufmerksamkeitsverteilung) umgesetzt und validiert. Die erfolgreiche Umsetzung des Diagnosekonzepts und die bestätigte Validität der Diagnoseergebnisse von RASMUS ermöglicht es, die Echtzeitdiagnose künftig als Grundlage für die dynamische Auswahl und Konfiguration von Unterstützungsstrategien in adaptiven Systemen heranzuziehen. Darüber hinaus sind auch Einsatzmöglichkeiten im Bereich der Usability-Bewertung sowie in Training und Ausbildung denkbar, z.B. um gewünschte Trainingszustände gezielt hervorzurufen oder den Trainingserfolg zu bewerten.
Quark Coulomb Interactions and the Mass Difference of Mirror Nuclei
Creators: name: Horowitz, C. J.
name: Piekarewicz, J.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the Okamoto-Nolen-Schiffer (ONS) anomaly in the binding energy of mirror nuclei at high density by adding a single neutron or proton to a quark gluon plasma. In this high-density limit we find an anomaly equal to two-thirds of the Coulomb exchange energy of a proton. This effect is dominated by quark electromagnetic interactions---rather than by the up-down quark mass difference. At normal density we calculate the Coulomb energy of neutron matter using a string-flip quark model. We find a nonzero Coulomb energy because of the neutron's charged constituents. This effect could make a significant contribution to the ONS anomaly.
description: 4 pages, 2 figs. sub. to Phys. Rev. Lett
Tissue-specific coordinate regulation of enzymes of cholesterol biosynthesis: Sciatic nerve versus liver
Creators: name: Jurevics, Helga
name: Hostettler, Janell
name: Morell, Pierre
name: Toews, Arrel D
name: Roe, Elaine B
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Exposure of weanling rats to a diet containing the element tellurium results in specific inhibition of squalene epoxidase, an obligate enzyme in cholesterol biosynthesis. Liver responds to the resulting intracellular sterol deficit by up-regulating, in parallel and to the same extent, expression of mRNA for squalene epoxidase and for HMG-CoA reductase, the major rate-limiting enzyme in the pathway. This increased mRNA expression, coupled with additional translational and posttranslational activation of the pathway allows normal levels of cholesterol synthesis in liver despite tellurium-induced inhibition of squalene epoxidase. The response to tellurium challenge in sciatic nerve is very different. In this tissue, cholesterol synthesis is prominent because of the large amount of cholesterol required for synthesis and maintenance of myelin. Although nerve shows an initial (at 1 day) up-regulation of mRNA expression for both enzymes in response to tellurium exposure, this is followed quickly by parallel down-regulation of both enzymes, in concert with down-regulation of mRNA expression for myelin proteins. We suggest that the tellurium-induced deficit in sterols leads to a coordinate down-regulation of synthesis of myelin components. The initial early up-regulation of cholesterol biosynthesis in sciatic nerve due to the cholesterol deficit is countered by down-regulation which is coordinated with overall control of the program of myelin assembly. This tissue-specific control of cholesterol synthesis in sciatic nerve is a point of vulnerability to toxicants, and may be related to the need for coordinate synthesis of all components of myelin.
Sources of cholesterol during development of the rat fetus and fetal organs
Creators: name: Morell, P
name: Jurevics, H A
name: Kidwai, F Z
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1997

description: Female rats at various stages of pregnancy were injected intraperitoneally with [3H]water; 4 h later, they were killed, the uterus was removed, and the fetuses were dissected. Lipids were isolated and fractionated by HPLC and the total amount of cholesterol in each organ, as well as radioactivity incorporated into cholesterol and cholesterol precursors, were determined. From the data for cholesterol content at each age we calculated the rate of accumulation of cholesterol during fetal development. As incorporation of label from [3H]water takes place with a stoichiometry defined by a known biosynthetic pathway, we were also able to determine the fraction of cholesterol accumulating in each organ that had been newly synthesized. For the fetus as a whole, more than 93% of the cholesterol accumulating during development was newly synthesized. As the specific radioactivity of cholesterol in the maternal circulation was negligible (because synthesis of cholesterol by maternal liver was suppressed by inclusion of cholesterol in the diet), we conclude that the fetus synthesizes nearly all of its own cholesterol; neither the maternal circulation nor the placenta/yolk sac contribute significant amounts of cholesterol to the fetus. We were also able to quantitate trafficking of cholesterol between fetal organs. Fetal brain is responsible for the synthesis of all of its own cholesterol. In contrast, fetal liver exports cholesterol into the fetal circulation and supplies about half of the cholesterol for development of heart, lung, and kidney.
Neutral lipid storage disease: a genetic disorder with abnormalities in the regulation of phospholipid metabolism
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1998

description: Neutral lipid storage disease (NLSD) is an autosomal recessive disorder characterized by the presence of numerous lipid droplets in virtually all tissues examined. The increased cellular triacylglycerol content results from defective recycling of triacylglycerol-derived diacylglycerol to phospholipids (Igal, R. A. and R. A. Coleman. 1996.
title: ADCO, Cartulaire de Fontenay, premier fragment (XIIIe siècle), Cart. 201 (15 H 9), 175 folios, f. 069r
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Fontenay, premier fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), 175 folios. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Fontenay, premier fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), 175 folios, f. 069r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: http://www.wikidata.org/entity/Q464918
description: Provenance: abbaye de Fontenay
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb119679755
description: Provenance: https://www.geonames.org/7874015
description: Provenance: http://www.idref.fr/027691802/id
Gamma photons from parametric resonance in neutron stars
Creators: name: Garcia-Bellido, Juan
name: Kusenko, Alexander
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Shock waves in cold nuclear matter, e.g. those induced by a collision of two neutron stars, can generate a large number of gamma photons via parametric resonance. We study the resonant production of gamma rays inside a shocked neutron star and discuss the possible astrophysical consequences of this phenomenon.
description: 5 pages, ReVTeX, 5 figures inserted with epsf; replaced with a final version (minor changes)
Pheidole macracantha Wilson, 2003, new species
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole macracantha

description: Pheidole macracantha new species
Types Mus. Comp. Zool. Harvard.
Etymology Gr macracantha, large thorn, alluding to propodeal spine.
Diagnosis Tentatively placed in the tristis group because of its larger size, macracantha is similar to cataphracta of the punctatissima group, differing in the minor caste as follows: much larger; occiput in full face strongly convex instead of concave; pilosity denser and longer; first gastral tergite mostly shagreened.
measurements (mm) Holotype minor: HW 0.72, HL 0.76, SL 0.78, EL 0.12, PW 0.46.
Color Concolorous yellow.
range Known only from the type locality.
Biology Unknown.
Figure Holotype, minor. PANAMA: Guipe (J. Zetek). Scale bar = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 717