cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Thermal and structural analyses of the multistage depressed collector of a traveling wave tube
Creators: name: Damacharla, Mallikarjuna Rao
Publisher: name: University of Utah
Year: 2012
Subjects: Amplifiers
TWT

description: The traveling wave tube (TWT) is often used as a power amplifier in various  applications such as broadcasting, radar and space communications. For an efficient  performance of a TWT, it requires an optimal design and thorough analysis of every  element in the TWT. In this work, a steady state thermal and structural analysis of the  collector portion of TWT using a commercial finite element code, ANSYS 7.0, is  performed. The collector portion of TWT is chosen, as two-thirds of the heat dissipation  occurs in this region. Electromagnetic data obtained from MICHELLE®, a collector  modeling tool, are mapped and interfaced with the ANSYS load data. The mesh  generated using ANSYS ICEM CFD 11.0 is used by the preprocessors of MICHELLE®  and ANSYS 7.0. A ceramic insulator is modeled and mated using the contact elements  with the imported mesh model of the collector. Suitable materials for the collector sleeve  are also analyzed. The effect of brazing technique on the model is studied and  demonstrated by varying the thermal contact conductance between the collector  electrodes and the ceramic insulator. The collector model is analyzed for best case and  worst case scenarios of electron distribution.  Analysis results indicate that a maximum temperature of 74.8°C and a maximum  stress of 175.9 MPa occur in the inner region of the collector electrodes for the best case  scenario. The results show that the proposed design is well within the safety limits. A  major portion of this work can be contributed towards the path chosen in mapping the MICHELLE1* output data with the ANSYS load input data. The present study also  focuses on the challenges encountered at various stages starting from the preprocessor  stage of mesh optimization to the postprocessor stage of analyzing the collector results. In  this work, an appropriate fin design for the collector model has been proposed.
Sonnenfleckenzeichnung Nr. 23278.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.02.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
View through a prism : a critical reflection on power relations and deviance in the development of psychiatric mental health nursing
Creators: name: Burrell, Patricia M.
Publisher: name: University of Utah
Year: 2012
Subjects: Social Perception
Stereotyping

description: This is a critical reflection on power relations and deviance in the development of nursing in general, and psychiatric nursing in particular.  Deviance and power in regards to nursing's legitimization are examined.  In light of nursing's interdependence on the social, economic, and political ramifications of the everyday world, a critical reflection of the varying perspectives of deviance and power, specifically utilizing principles from Foucault, as a form of cultural analysis were used to attain a differing perspective.  Power relations and struggles have always existed.  One of Foucault's major premises is that power is all pervasive throughout the social body.  There is a constant tension and interplay between the effects of power and the effects of resistances to that power.  Power is examined from varying perspectives.  There is an in depth focus on Foucault's principles, propositions and precautions in examination of power.  Foucault proves helpful in refocusing our view of history, from that of a single continuous thread to one that is a result of a series and various sets of struggles and resistances to power.  It is this perspective that is utilized in the history of nursing focusing on power relations and spheres of influences.  Nursing's failure to critically examine deviance, in light of its mandate to intervene is also examined.  Varying perspectives of deviance are examined and the ramifications to nursing practice are addressed.  Competing paradigms, in regard to power and the perceived needs of nursing and its clientele are addressed.  Critical reflection on power and deviance is proposed as one method of being in the world and furthering the profession, in light of the exigencies of nursing's world.
New pyran derivative with antioxidant and anticancer properties isolated from the probiotic Lactobacillus plantarum H24 strain
Creators: name: Momo, Chancel Hector Kenfack
name: Mboussaah, Alex Doris Kengni
name: Zambou, Ngoufack François
name: Shaiq, Muhammad Ali
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: This work was aimed to prepare, isolate and identify antioxidant and cytotoxic compound from the culture filtrate of a probiotic lactobacillus strain. New compound, plantarone (1), together with two known compounds, kojic acid (2) and methyl dodecanoate (3), were isolated from the ethyl acetate extract of the culture filtrate of probiotic Lactobacillus plantarum H24. Their structures were elucidated using spectroscopic methods including 2 D NMR, HRMS analyses. Isolated compounds were screened for antioxidant and cytotoxic activities against Caco-2 colon cancer cells. Compounds 1 and 2 showed lowers DPPH radical scavenging activities (p < 0.05) with IC50 values of 66.3 ± 0.34 μM and 50.2 ± 0.28 μM respectively, compared to standard butylated hydroxyanisole (BHA: IC50 = 44.2 ± 0.24 μM). Whereas only compound 1 showed a good cytotoxicity activity with inhibition value of 60.72 ± 3.55%. Accordingly, L. plantarum H24 could be used to prevent oxidative stress and its injuries, improving human health.
Praktische Konzeption "EDV-gestützte Kommunikation in der Familialen Pflege". Modul 4: Organisationsentwicklung und Prozessgestaltung
Creators: name: Waterböhr, Jan-Willem
name: Kühn, Marco
Publisher: name: Universität Bielefeld
Year: 2018
Subjects: subject: 360
subject: Familiale Pflege
subject: Krankenhaus
subject: Organisationsentwicklung
subject: Prozessmanagement
subject: Krankenhausinformationssystem
subject: Beratung
subject: Best Practice
subject: Demenz im Krankenhaus
subject: Organisationsberatung
subject: Strategiebildung
subject: kollegiale Zusammenarbeit
subject: Netzwerke
subject: eAkte
subject: Kommunikation
subject: elektronische Dokumentation
subject: Krankenhausplanung

description: Das vorliegende Modul rahmt unter der Perspektive der Organisationsentwicklung die Module 1-3, die bisher einzelne Aspekte zur Integration der Familialen Pflege in die Aufnahme- und Entlassungsprozesse sowie in das KIS thematisiert haben. Damit werden im Folgenden die Fragen der Beauftragung, der Dokumentation und der kollegialen Zusammenarbeit in einen größeren, abstrakteren Kontext gestellt, der das Krankenhaus als Organisation und dessen Prozessentwicklung in den Blick nimmt. Die zentrale Frage, wie pflegende Angehörige noch während des Krankenhausaufenthalts identifiziert werden können und die Familiale Pflege als Teil der Entlassungsprozesse implementiert werden kann, wird ergänzend aus der Perspektive der Organisations- und Prozessentwicklung betrachtet.
Phytochemical constituents, antimicrobial and antioxidant activities of Kumaun Himalayan Hoop Pine bark extract
Creators: name: Kumar, Parikshit
name: Sati, S. C.
name: Khulbe, Kapil
name: Pant, Prabha
name: Tripathi, Amrendra Nath
name: Sarvendra, Kunwar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: Hematology
subject: Plant Biology

description: The chemical composition of the methanol extract obtained from Araucaria cunninghamii Sweet. bark was determined by GC-MS analysis with its antioxidant and antibacterial potential, for the first time. A total of 73 compounds were identified and the extract was strongly characterised by Viridiflorene; Androstan-17-one, 3-ethyl-3-hydroxy-, (5α)-; 8-Isopropenyl-1,3,3,7-tetramethyl-bicyclo[5.1.0]oct-5-en-2-one; 3,6,9-Triethyl-3,6,9-trimethyl-tetracyclo[6.1.0.0 ∼ 2,4∼.0 ∼ 5,7∼]-nonane; Longifolenaldehyde; (-)-Caryophyllen-(I1); 2-hydroxymethyl-5-furfural; Methyl commate B; 3-Ethyl-3-hydroxyandrostan-17-one; 3-Hydroxybenzoic acid as the main components (55.39%). A. cunninghamii extract presents IC50, 53.52 µg/mL and 65.29 µg/mL using DPPH and H2O2 scavenging assay, respectively. The antibacterial activity of the extract was evaluated for eight microorganisms showed that the extract had a remarkable inhibitory potential with a mean zone diameter of inhibition ranging from 09 to 21 mm. The methanol extract of A. cunninghamii showed significant antibacterial activity against X. campestris (21 mm, ZOI) with MIC and MBC values 15.6 and 31.25 µg/mL, respectively.
Sonnenfleckenzeichnung Nr. 23307.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.03.1970, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 23267.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.01.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Liposomal formulations of mistletoe produced by centrifugal technologies and cell proliferation analysis of both mistletoe extracts and isolated mistletoe lectin I = Liposomale Formulierung von Mistelextrakten durch Zentrifugationsverfahren und Analyse der Zellproliferation von Gesamtextrakten und isoliertem Mistellektin I
Creators: name: Hildebrandt, Ellen
name: Heyder, Christoph
name: Matos, Maria B. C. De
name: Beztsinna, Nataliia
name: Kok, Robbert Jan
name: Nirschl, Hermann
name: Leneweit, Gero
Publisher: name: Karlsruhe
Year: 2016
Subjects: Liposomes
heparin immune protection
mistletoe extracts
mistletoe lectin
cytotoxicity
growth inhibition
proliferation assay
murine cell lines
Liposomen
Heparin Immunschutz
Mistelextrakte
Mistellektin
Zytotoxizität
Wachstumsinhibition
Proliferationstest
Mauszellinien

description: Um Liposomen aus Nanoemulsionen herzustellen, wird ein Zentrifugationsverfahren entwickelt, das eine hohe Einkapselungseffizienz und asymmetrische Membranen ermöglicht. Heparin-Komplexe werden für die Bildung einer stabilen Schutzschicht verwendet. Um die Erprobung der liposomalen Formulierungen in vitro und in vivo zu ermöglichen, wurden Mistelpräparate mit unterschiedlicher Viscotoxin-(VT) und Mistellektin-(ML) Zusammensetzung sowie isoliertes ML°I an Maus-Zelllinien erprobt. Ein Proliferationstest wurde durchgeführt, um die inhibierenden Konzentrationen (IC50) zu ermitteln und sensitive Zelllinien für in vivo Experimente auszuwählen. abnobaVISCUM (AV) Pini Präparate, die den geringsten Gesamtgehalt an ML und eine Dominanz von ML III aufweisen, zeigten bei B16-F10 Melanomzellen eine stärkere Inhibierung der Proliferation im Vergleich zu den ML I reichen Präparaten AV Fraxini und Quercus. Für AV Fraxnini und AV Quercus wurde gezeigt, dass die Zytotoxizität überwiegend auf ML I zurückzuführen ist und ML I daher als potentieller Wirkstoff zur Verkapselung in Liposomen geeignet ist. Auf isoliertes ML I reagiert die getestete Kolonkarzinomzelllinie C26 deutlich empfindlicher als die aggressive B16-F10 Melanomzelllinie. Diese Ergebnisse erlauben den Vergleich eines sensitiven mit einem aggressiven Tumormodell in vivo. Im Vergleich zu C26 ist die Makrophagenzelllinie RAW264.7 relativ unempfindlich gegenüber isoliertem ML I. Die Ergebnisse deuten auf die Möglichkeit einer gezielten Therapie von z.B. Kolontumoren hin, bei der die Immunfunktionen intakt bleiben.
Effects of teaching on the recovery patterns of postpartum women
Creators: name: Bushong, Michelle
Publisher: name: University of Utah
Year: 2012
Subjects: Postnatal care

description: The purpose of this study was to determine whether or not giving women additional teaching and a postpartum restoration prescription in both the antenatal and postnatal periods would affect their postpartum recovery patterns.  The research method use was a quasi-experimental design utilizing four study groups:  three experimental and one control.  Sixty-three women, multipara and primiparas, comprised the study sample.  Each subject was randomly placed into one of the four study groups.  Subjects in the first group received a teaching session at approximately 8 months gestation, an additional teaching session in the hospital within 48 hours of delivery, and a postpartum prescription.  Subjects in group 2 received a teaching session in the hospital within 48 hours of delivery and a postpartum prescription.  Subjects in group 3 received a teaching session within 48 hours postdelivery.  Group 4 served as the control group.  All subjects answered a questionnaire consisting of six scales assessing the subjects perception of their resolution of five major postpartum tasks.  By random assignment, subjects were placed into two groups.  Group 1 responded to the questionnaire every 2 weeks for 6 weeks, and Group 2 every 1 week for 6 weeks.  Data analysis revealed an interruption in resolution of postpartum tasks at 3 weeks.  This appears to be due to a decrease in available help in the home.  Women at this time must devote more energy to resuming household responsibilities and less energy to resolution of their five postpartum tasks.  Data analysis also revealed that those women who had complications in labor, delivery and postpartum or who had a cesarean section needed more energy for physical recovery and therefore displayed less complete resolution of other postpartum tasks than did those women who had not complications and vaginal births.  Data analysis did not lend some support to the usefulness or postpartum teaching and uses of a postpartum restoration prescription in improving postpartum recovery patterns.  Recommendations for further study and for postpartum care are included.
Cambodia's Imminent Graduation from Least Developed Country Status: What Will be the Impact of the TRIPS Agreement on Access to HIV and Hepatitis C Medicines in Cambodia?
Creators: name: Tenni, Brigitte
name: Lexchin, Joel
name: Phin, Sovath
name: Gleeson, Deborah
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 4206
subject: Public health

description: Cambodia has experienced exponential economic growth in recent years and is expected to graduate from least developed country (LDC) status within the next decade. Membership of the World Trade Organization (WTO) will require Cambodia to grant product and process patents for pharmaceuticals upon LDC graduation. This study aims to measure the impact of the WTO Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) on the price of HIV and hepatitis C medicine in Cambodia once it graduates from LDC status and is obliged to make patents available for pharmaceutical products and processes. Using scenarios based on likely outcomes of accession to the TRIPS Agreement, it measures the impact on the price of the HIV treatment program and compares that impact with the hepatitis C treatment program. Graduation from LDC status would be expected to result in a modest increase in the cost of the antiretroviral (ARV) treatment program and very large increases in the cost of the direct acting antivirals (DAA) treatment program. If annual treatment budgets remain constant, patent protection could see 1,515 fewer people living with HIV able to access ARV treatment and 2,577 fewer people able to access DAA treatment (a drop in treatment coverage of 93%).
Leucothyreus stibeutes Ohaus 1924
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Leucothyreus
Leucothyreus stibeutes

description: Leucothyreus stibeutes Ohaus, 1924
Leucothyreus stibeutes Ohaus 1924: 183 (Guyana)
Distribution. Guyana: Ohaus 1924: 183; Blackwelder 1944: 249; Machatschke 1972: 354; Jameson and Hawkins 2005: 48. Suriname: MHCN - NEW COUNTRY RECORD (Suriname, Sipaliwini.).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 125, DOI: 10.5281/zenodo.3678492
Synthesis and in vitro antiproliferative activities of lupanol derivatives towards human esophageal squamous carcinoma cells
Creators: name: Li, Weijie
name: Xiao, Yeyu
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: A series of lupanol derivatives were synthesized and evaluated in vitro for their inhibitory activities against three human esophageal squamous carcinoma cells lines, Eca-109, TE-1 and EC-9706. Among lupanol derivatives, seven were new compounds, and lupanol cinnamate analogues 5 and 6, hydrazone analogues 9 and 10 presented high activities towards all the tested tumour cells, even higher activities than those of doxorubicine.
Effects of a nutrition intervention program during pregnancy:  phase three
Creators: name: Jenniges, Katherine and  Rigney
Publisher: name: University of Utah
Year: 2012
Subjects: Pregnancy - Nutritional aspects

description: This study sought to identify the effects of an individual prescription for protein and kilocalorie requirements during pregnancy on subsequent maternal and infant outcomes using an experimental control group with 28 subjects in phase one, 15 subjects in phase two, and 23 subjects in phase three, for a total of 66 subjects. The method of nutritional counseling was found to have a significnat impact on increasing the amounts of protein (p=.03) and kilocalories (p=.04) consumed by the experimental group in the combined phases; findings indicate that those subjects who ate an adequate amount of both protein and kilocalories showed a trend towards larger birthweight infants than those who had inadequate nutritional intake (p=.06). However, those women who had an adequate early weight gain in addition to adequate prescription ingestion as compared to those with inadequate early weight gain and inadequate prescription ingestion gained significantly more weight (p=.002) and also showed a trend toward higher birthweight infants (p=.07).
Evaluation of ternary blended cements for use in transportation concrete structures
Creators: name: Gilliland, Amanda Louise
Publisher: name: University of Utah
Year: 2012
Subjects: Blended cement
Cement
Concrete
Fly ash
Slag
Ternary
Transportation structures
Concrete structures

description: This thesis investigates the use of ternary blended cement concrete mixtures for transportation structures. The study documents technical properties of three  concrete mixtures used in federally funded transportation projects in Utah, Kansas, and Michigan that used ternary blended cement concrete mixtures. Data were also collected from laboratory trial batches of ternary blended cement concrete mixtures with mixture designs similar to those of the field projects. The study presents the technical, economic, and environmental advantages of ternary blended cement mixtures. Different barriers of implementation for using ternary blended cement concrete mixtures in transportation projects are addressed.  It was concluded that there are no technical, economic, or environmental barriers that exist when using most ternary blended cement concrete mixtures. The  technical performance of the ternary blended concrete mixtures that were studied was always better than ordinary portland cement concrete mixtures. The ternary  blended cements showed increased durability against chloride ion penetration, alkali silica reaction, and reaction to sulfates. These blends also had less linear  shrinkage than ordinary portland cement concrete and met all strength requirements.  The increased durability would likely reduce life cycle costs associated with concrete pavement and concrete bridge decks. The initial cost of ternary mixtures can be higher or lower than ordinary portland cement, depending on the supplementary cementitious materials used.  Ternary blended cement concrete mixtures produce less carbon dioxide emissions than ordinary portland cement mixtures. This reduces the carbon footprint of construction projects.  The barriers associated with implementing ternary blended cement concrete for transportation projects are not significant. Supplying fly ash returns any  investment costs for the ready mix plant, including silos and other associated equipment. State specifications can make designing ternary blended cements more  acceptable by eliminating arbitrary limitations for supplementary cementitious materials (SCMs) use and changing to performance?based standards. Performance-based standards require trial batching of concrete mixture designs, which can be used to optimize ternary combinations of portland cement and SCMs. States should be aware of various SCMs that are appropriate for the project type and its environment.
Neurogenesis and pathogenesis of the dysraphic neural tube.
Creators: name: Keller-Peck, Cynthia Rae
Publisher: name: University of Utah
Year: 2012
Subjects: Birth Defects
Neurology
Cellular Biology

description: Defects in neurulation occur in roughly 4,000 pregnancies in the United States, and approximately 400,000 pregnancies worldwide each year. Infants born with caudal neural tube defects (NTDs) are usually paralyzed, with bowel and bladder incontinence. Numerous genetic loci and environmental agents interact to produce NTDs, making prevention of these defects difficult. Therefore, it is essential to begin to understand the postneurulation pathology that results in clinical disabilities. The purpose of this dissertation is to begin to explore this pathology.  The chapters herein examine the differentiation, organization, and proliferation of cells in the dysraphic neural tube of two mouse neural tube mutants, curly tail and splotch-delayed. The results of these studies suggest that closure of the neural tube is not essential for normal neuronal or glial differentiation between embryonic days 12 and 15 (E12-E15). However, maturation of the spinal cord is halted after E16, when a massive deterioration of the neural tissue begins. Additionally, our results suggest that the temporal pattern of cell proliferation is similar between normal and affected embryos. By contrast, the number of postmitotic cells in affected embryos is significantly increased during several days of gestation. Measurements of the volume of neuronal tissue suggested that more neurons were born in affected embryos than the control. Thus, failure of the neural folds to close may adversely affect the quantity of proliferation.  In addition to the experiments described above, we also examined the percentage of embryos born with spina bifida in the curly tail strain. The results suggest that the incidence of NTDs in this mutant is much lower than reported in the literature. The final study examined the location of mitotic figures in spina bifida embryos to determine whether cells undergo mitosis within the ventricular zone. The outcome of this study revealed that the nuclei of dividing cells are able to translocate to the ventricular zone.
Update Schweiz: Nationale Open Access Strategie und Verhandlungen mit Grossverlagen
Creators: name: Felder, Fabian
name: Lochbühler, Wilfried
Publisher: name: Zenodo
Year: 2020
Subjects: Open-Access-Strategie, Open-Access-Verhandlungen, Konsortien

description: Die nationale Open Access Strategie der Schweiz (2017) mit Aktionsplan (2018) sieht vor, dass alle bis 2024 öffentlich finanzierten wissenschaftlichen Publikationen Open Access zugänglich sein sollen. Die Umsetzung ist inzwischen an den Hochschulen in zentralen Handlungsfeldern angelaufen. Der Beitrag gibt einen aktuellen Überblick über den Stand der Umsetzung. Ein wichtiges Element sind die laufenden Verhandlungen mit den Grossverlagen Elsevier, Wiley und Springer unter der Leitung von swissuniversities. Ein Ausblick fokussiert auf neue Ansätze zu einer nationalen Open Science Strategie in der Schweiz.
Sonnenfleckenzeichnung Nr. 23301.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.03.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
In vitro anti-trypanosomal potential of kaurane and pimarane semi-synthetic derivatives
Creators: name: Rocha, Ana Carolina F. S.
name: Morais, Gustavo O.
name: da Silva, Marcela M.
name: Kovatch, Pedro Y.
name: Ferreira, Daniele S.
name: Esperandim, Viviane R.
name: Pagotti, Mariana C.
name: Magalhães, Lizandra G.
name: Heleno, Vladimir C. G.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: As part of the search for anti-trypanosomal agents, this work presents the production of sixteen derivatives. All of them were obtained from two natural diterpenes, one with kaurane skeleton (ent-kaurenoic acid) and other with a pimarane skeleton (ent-pimaradienoic acid). Then, the eighteen compounds were assayed against epimastigote form of Trypanosoma cruzi, with the derivatives showing increase of activity in relation to their precursors. Moreover, the most active derivative presented an IC50 <12.5 µM (estimated 0.8 µM), lower than Benznidazole (IC50 = 9.8 µM), used as control. The esterification of acid diterpenes showed to be an interesting way in the search for anti-trypanosomal agents.
Leucothyreus vayanus Ohaus 1917
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Leucothyreus
Leucothyreus vayanus

description: Leucothyreus vayanus Ohaus, 1917
Leucothyreus vayanus Ohaus 1917: 9 (French Guiana)
Distribution. French Guiana: Ohaus 1917: 9; Blackwelder 1944: 249; Machatschke 1972: 354; Jameson and Hawkins 2005: 49; Soula 2010a: 59.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 125, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.01.1970, erstellt von Gisèle Evrard-Kesteloot, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Hyaluronan based biomaterial for antiadhesion and thermosensitive hyaluronan lanthanide complexes
Creators: name: Li, Hao
Publisher: name: University of Utah
Year: 2012
Subjects: Biosynthesis
Mitomycin C

description: Hyaluronan (HA) is a naturally-occurring polysaccharide abundant in the extracellular matrix (ECM). The unique physicochemical properties and biological functions of HA make it suitable for applications in drug delivery, anti-adhesion and tissue engineering. Studying new HA properties and developing novel HA based biomaterials will contribute to medical and pharmaceutical applications. HA-lanthanide complexes were discovered to exhibit thermosensitive properties. Addition of trivalent lanthanide salts to solutions of HA resulted in an unexpected reverse-temperature phase transition (RTPT), i.e., the complexes were soluble when cooled but precipitated when warmed. A unique lower critical solution transition temperature (LCST) was observed for each lanthanide in the order (increasing LCST) Eu3+ < Nd3+< Ce3+ < Gd3+ < La3+ < Tb3+ < Dy3+ < Yb3+ < Lu3+ for high molecular weight HA. Moreover, the LCST values increased as the molecular weight of the HA decreased from 1730 kDa to 190 kDa. The precipitation-dissolution behavior was fully reversible in a cyclical fashion; a lag in redissolution was observed as the temperature was lowered, and longer incubation times at each temperature minimized this lag. The RTPT behavior could be ablated by titration with 8 kDa HA to produce complexes soluble at ambient temperature. This is the first description of RTPT behavior in a biologically important glycosaminoglycan (GAG).  A novel HA material was developed with significant anti-adhesion efficacy.  Mitomycin C (MMC) was modified with acryloyl chloride and covalently conjugated to a thiolated HA derivative. The HA-thiopropanoyl hydrazide-MMC derivative (HA-DTPH-MMC) was cross-linked with poly(ethylene glycol)-diacrylate (PEGDA) and evaporated into a film. MMC was released from the film by hydrolysis. The films with different MMC loadings had similar releasing kinetics and released MMC was proportional to the MMC loading. To evaluate the efficacy in reducing postoperative adhesion formation, the film was applied in a rat uterine horn adhesion model. The extent and severity of adhesions was greatly reduced in a dose-dependent way by HA-DTPH-MMC-PEGDA barriers. In vivo biocompatibility studies showed that MMC coupling did not evoke a severe peritoneal fluid leukocyte response through day 3 after film insertion. This film was demonstrated to be an attractive biomaterial for anti-adhesion usage.
Acetylcholinesterase inhibitory activity of Ocotea pomaderroides extracts: HPLC-MS/MS characterization and molecular modeling studies
Creators: name: Reis, Isabella M. A.
name: Cassiano, Dayse S. A.
name: Conceição, Rodrigo S.
name: de Freitas, Humberto F.
name: da R. Pita, Samuel S.
name: David, Jorge M.
name: Branco, Alexsandro
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology

description: The present work describes the acetylcholinesterase inhibitory activity of Ocotea pomaderroides extracts besides the chemical composition of chromatographic fractions. The hexane, dichloromethane and ethyl acetate extract soluble fractions showed high Electrophorus electricus acetylcholinesterase (EelAChE) inhibition (92.18, 71.86 and 74.25%, respectively) while the butanolic and aqueous extracts showed moderate to low activities (44.48 and 20.74%, respectively). The high-performance liquid chromatography coupled with electrospray ionization multiple-stage mass spectrometry (HPLC-ESI-MSn) analysis led to the identification of the alkaloids and flavonol glycoside derivatives present in these extracts. The binding profile of the alkaloids and their atomic effect on 3D structure of Electrophorus electricus AchE (EelAChE) were assessed with molecular modeling.
Nurse practitioner practice management.
Creators: name: Tulloch, Janet Elizabeth
Publisher: name: University of Utah
Year: 2012
Subjects: Health Care
Rural Health

description: Thirty nurse practitioners in clinical practice in rural Idaho and Utah responded to a questionnaire determining the level of decision making regarding managerial tasks, level of perceived managerial adequacy, and level of perceived managerial adequacy, and level of management training obtained by the respondent.  No empirical studies about nurse practitioner practice management have been published. Various component functions of the management process were described in the general literature.   The most relevant to clinical practice management were planning, organizing, directing, controlling, and coordinating.  The conceptual framework for the study was general systems theory.  The focus was the regulatory process manifested by the employee subsystem in the form of managerial task function within the focal practice system.  The instrument was a questionnaire designed by the investigator.  Each participant returned the complete questionnaire to the investigator within a set time period of two months.  Since most of the data were nominal and ordinal, the principal analysis was through frequency distributions, percentages, Chi-square analysis, and Pearson Product-Moment correlations.  Rural nurse practitioners in Utah and Idaho were found to exhibit active participation in protocol production and use, and it setting objectives for clinical practice.  Rural nurse practitioners were found to exhibit no participation in financial or monetary planning and control, or in coordination of the internal practice system.  A small minority of the rural nurse practitioners consistently performed all five functions of clinical practice management process.  The participatory minority exhibited the characteristics of the highest income level ($25,000+ per year), the higher age level (36+ years old), and masters level education preparation.  The rural nurse practitioners exhibited perceived inadequacy to perform financially oriented management tasks for the clinical practice.  The respondents had no formal management training.  Further study is recommended to clarify empirically nurse practitioner clinical practice management behaviors with an instrument presenting interval level data enabling a more sophisticated analysis.
Comparison of discovery and didactic instruction in medical technology
Creators: name: Hengesbaugh, Jean Susan Houger
Publisher: name: University of Utah
Year: 2012
Subjects: Teacher/Student Roles
Study
Didactic Instruction

description: A comparison of the effectiveness of discovery and didactic instruction in medical technology was done using twenty university sophomores and juniors. A pre- and post-test design was used. Two treatment groups received differing instructional strategies during discussions once a week with both groups receiving the same lecture material and laboratory competency requirements during a full quarter's work. The results indicate neither the didactic or discovery learning approach was more effective using group mean gain scores on the pre- and posttests and the final examination. The sophomores and juniors within each group also showed no significant differences on the pre- and posttests. An attitudinal rating scale distributed each week following the discussion period showed the students as having increased verbal participation, slightly increased frustration levels, increased interest, increased motivation for further study, and increased overall enjoyment of the discovery learning sessions compared to the didactic sessions.
Sonnenfleckenzeichnung Nr. 23329.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.04.1970, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Lobogeniates Ohaus 1917
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Lobogeniates

description: LOBOGENIATES Ohaus, 1917
Lobogeniates Ohaus 1917: 28
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 125, DOI: 10.5281/zenodo.3678492
Geology and diatremes of Desert Mountain, Utah
Creators: name: Rees, Delbert Clyde
Publisher: name: University of Utah
Year: 2012
Subjects: Geology -- Utah -- Desert Mountain
Thesis and dissertation georeferencing project

description: The Desert Mountains and the Allison Knolls make up a group of isolated peaks which rise from part of the Bonneville lake plain. The area is in Juab County and is located about 24 miles west of Jericho and about 35 miles north of Delta.  Sedimentary rocks are exposed in the northeast part of the area. They consist of Precambrian Sheeprock Series and Ordovician Fish Haven Dolomite. The older rock has been thrust on top of the dolomite by what is probably the Sheeprock Thrust.  Most of the bed rock exposed in the area is intrusive. Two distinct intrusive rocks are present. The older is a very dark colored granodiorite. The other, is a light colored granite. Aplite, pegmatite and lamprophyre dikes cut the granite.  A diatreme complex is located east of Desert Mountain The complex is characterized by an igneous matrix which ha fragments and large blocks of dolomite, quartzite, slate, jasperoid, and igneous rocks suspended in it. Extrusive rocks occur mainly in the eastern part of  the area. All the volcanics are thought to be equivalents of the Keg Mountain Ignimbrites. Two volcanic units are altered and apparently correlate with the older recks of the Keg Mountain Ignimbrites.  The structure is dominated by three shear directions, sheeting, and thrust fault mentioned above. The three shear directions form a pattern similar to patterns produced by model work from strike-slip stresses. The pattern is also similar to rock fracture patterns under compression. These similarities together with the general east-west alignment of intrusions and volcanic vents, suggests that there is deep-seated structure control with left-lateral  movement. Hydrothermal alteration occurs in many areas but generally is weak. Locally the alteration is moderately strong. Some small copper deposits occur in the western part of the area but they are too small to be of economic Interest.
Studies in Arabic literary papyri
Creators: name: Samji, Karim
Publisher: name: University of Utah
Year: 2012
Subjects: Manuscripts, Arabic (Papyri)

description: The thesis addresses the historiographical and methodological impasse in Arabic manuscript research. The first part of the thesis examines the authenticity debate in historical circles between the descriptivist and revisionist schools, followed by an analysis of the methodological problems faced in the criticism of prophetic logia {hadith). In light of these considerations, the codicological approach is advanced as an alternate conceptual schema. Subsequently, a case study of Ms Or.P443 is provided to demonstrate the efficacy of the proposed method.  The second part of the thesis provides the editions, translations, commentaries, and significance of six Arabic literary papyri from the Aziz S. Atiya Papyri and Paper Collection at the University of Utah. The six Arabic literary papyri comprise materials from both hadith and Islamic moral law ifiqh). The papyri include Ms Or.P173, P205, P365, P443, P518, and P521. These specific papyri address a variety of issues relating to the development of hadith sndfiqh. The publication of these papyri will prove to be a substantial contribution to the understanding of the evolution of these traditions.
New pyran derivative with antioxidant and anticancer properties isolated from the probiotic Lactobacillus plantarum H24 strain
Creators: name: Momo, Chancel Hector Kenfack
name: Mboussaah, Alex Doris Kengni
name: Zambou, Ngoufack François
name: Shaiq, Muhammad Ali
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: This work was aimed to prepare, isolate and identify antioxidant and cytotoxic compound from the culture filtrate of a probiotic lactobacillus strain. New compound, plantarone (1), together with two known compounds, kojic acid (2) and methyl dodecanoate (3), were isolated from the ethyl acetate extract of the culture filtrate of probiotic Lactobacillus plantarum H24. Their structures were elucidated using spectroscopic methods including 2 D NMR, HRMS analyses. Isolated compounds were screened for antioxidant and cytotoxic activities against Caco-2 colon cancer cells. Compounds 1 and 2 showed lowers DPPH radical scavenging activities (p < 0.05) with IC50 values of 66.3 ± 0.34 μM and 50.2 ± 0.28 μM respectively, compared to standard butylated hydroxyanisole (BHA: IC50 = 44.2 ± 0.24 μM). Whereas only compound 1 showed a good cytotoxicity activity with inhibition value of 60.72 ± 3.55%. Accordingly, L. plantarum H24 could be used to prevent oxidative stress and its injuries, improving human health.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.02.1970, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.04.1970, erstellt von Vasile Dinulescu, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung Nr. 23303.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.03.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt