cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ultrafast terahertz spectroscopy study of Kondo insulating thin film SmB$_{6}$: evidence for an emergent surface state
Creators: name: Zhang, Jingdi
name: Yong, Jie
name: Takeuchi, Ichiro
name: Greene, Richard L.
name: Averitt, Richard D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We utilize terahertz time domain spectroscopy to investigate thin films of the heavy fermion compound SmB6, a prototype Kondo insulator. Temperature dependent terahertz (THz) conductivity measurements reveal a rapid decrease in the Drude weight and carrier scattering rate at ~T*=20 K, well below the hybridization gap onset temperature (100 K). Moreover, a low-temperature conductivity plateau (below 20K) indicates the emergence of a surface state with an effective electron mass of 0.1me. Conductivity dynamics following optical excitation are also measured and interpreted using Rothwarf-Taylor (R-T) phenomenology, yielding a hybridization gap energy of 17 meV. However, R-T modeling of the conductivity dynamics reveals a deviation from the expected thermally excited quasiparticle density at temperatures below 20K, indicative of another channel opening up in the low energy electrodynamics. Taken together, these results suggest the onset of a surface state well below the crossover temperature (100K) after long-range coherence of the f-electron Kondo lattice is established.
title: Tensions Rising to Breaking Point: A Multimodality Imaging Review of Bisphosphonate Related Atypical Femoral Fractures
Creators: name: Knipe, Henry
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2015
Subjects: subject: Bones
subject: Musculoskeletal bone
subject: Trauma
subject: Conventional radiography
subject: CT
subject: MR
subject: Complications
subject: Treatment effects
subject: Demineralisation-Bone
subject: Trauma

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To recognise the imaging appearances of atypical femoral fractures associated with bisphosphonate use and to better understand the mechanism of bisphosphonate related atypical...
Using avalanche problems to examine the effect of large-scale atmosphere-ocean oscillations on avalanche hazard in western Canada---Data and Code
Creators: name: Haegeli, Pascal
name: Mair, Patrick
name: Shandro, Bret
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Other Earth Sciences
subject: FOS: Earth and related environmental sciences
subject: Physical Sciences and Mathematics
subject: Oceanography and Atmospheric Sciences and Meteorology
subject: Atmospheric Sciences
subject: Earth Sciences
subject: Climate
subject: Avalanche Hazard

description: Contains the code, data and analysis results for Haegeli, P., Shandro, B., and Mair, P.: Using avalanche problems to examine the effect of large-scale atmosphere-ocean oscillations on avalanche hazard in western Canada, Submitted to The Cryosphere on May 30, 2020.
Thermal equilibrium of a macroscopic quantum system in a pure state
Creators: name: Goldstein, Sheldon
name: Huse, David A.
name: Lebowitz, Joel L.
name: Tumulka, Roderich
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider the notion of thermal equilibrium for an individual closed macroscopic quantum system in a pure state, i.e., described by a wave function. The macroscopic properties in thermal equilibrium of such a system, determined by its wave function, must be the same as those obtained from thermodynamics, e.g., spatial uniformity of temperature and chemical potential. When this is true we say that the system is in macroscopic thermal equilibrium (MATE). Such a system may however not be in microscopic thermal equilibrium (MITE). The latter requires that the reduced density matrices of small subsystems be close to those obtained from the microcanonical, equivalently the canonical, ensemble for the whole system. The distinction between MITE and MATE is particularly relevant for systems with many-body localization (MBL) for which the energy eigenfunctions fail to be in MITE while necessarily most of them, but not all, are in MATE. We note however that for generic macroscopic systems, including those with MBL, most wave functions in an energy shell are in both MATE and MITE. For a classical macroscopic system, MATE holds for most phase points on the energy surface, but MITE fails to hold for any phase point.
Mechanisms linking work and family: Clarifying the relationship between work and family constructs
Creators: name: Rothbard, Nancy P.
name: Edwards, Jeffrey R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Work-family research emphasizes the importance of mechanisms that link work and family. However, these mechanisms typically are described in metaphoric terms poorly suited to rigorous research. In this article we translate work-family linking mechanisms into causal relationships between work and family constructs. For each relationship we explain its sign and causal structure and how it is influenced by personal intent. We show how these respecified linking mechanisms constitute theoretical building blocks for developing comprehensive models of the work-family interface.
title: A Pilot Study of the Utility of Choline PET-CT in Prostate Cancer Patients with Biochemical Relapse Following Radical Prostatectomy
Creators: name: Tan, Hendrick
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2015
Subjects: subject: Neoplasia
subject: Radiation therapy / Oncology
subject: PET-CT
subject: Genital / Reproductive system male
subject: Oncology
subject: Nuclear medicine

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Altered choline metabolism has been demonstrated in prostate cancer [1]. Choline analogues have been studied in the last decade and have been shown to be superior to conventional imaging modalities in the detection of loco-regional or distant...
Assessment of Degradation and Performance Improvement of Railway Ballast with Geosynthetics - A Case Study of National Railway Network
Creators: name: Kedir Abdu
Publisher: name: Zenodo
Year: 2015

description: The increasing demands of higher axle loads, speeds and usage means understanding the ballast behavior and its interaction with the infrastructure remains a critical element to the design and successful operation of ballasted railway track, Therefore it is important to study the degradation of ballast to increase and predict ballast life on the track, reduce waste track, keep good track quality and minimize the frequency and cost of ballast replacement.
SPT 2-Channel Kondo Model in the Structure of Normal Metal/Quantum Dot/DIII-class Topological Superconductor
Creators: name: Gao, Zhen
name: Gong, Wei-Jiang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the Kondo effect in a structure which is constructed by embedding one quantum dot between a normal metal and a \emph{DIII}-class topological superconductor supporting Majorana doublets at its ends. It is observed that Kondo correlation occurs between the localized state in the dot and two continuum states simultaneously, i.e., the continuum state in the metal and the continuum Andreev reflection state between the metal and topological superconductor. As a result, the Kondo model Hamiltonian is topologically protected by the $SU(2)_s\rtimes Z_2^T$ symmetry. Besides, the Kondo temperature has an opportunity to present three forms in turn, following the enhancement of the coupling between the dot and Majorana doublet. This phenomenon exactly reflects the special role of Majorana doublet in tuning the Kondo effect.
description: 5 pages, 2 figures
title: Exclusion of Arterial Saccular Aneurysm Utilising Both Penumbra 400â'¢ Coils and Onyxâ'¢
Creators: name: Quek, Lawrence
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2015
Subjects: subject: Interventional vascular
subject: Catheter arteriography
subject: Embolisation
subject: Aneurysms

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: This poster showcases the combined use of neurovascular framing coils and liquid embolics to treat peripheral saccular...
Molecular Classification and Molecular Forecasting of Breast Cancer: Ready for Clinical Application?
Creators: name: Caldas, Carlos
name: Ahmed, Ahmed Ashour
name: Carey, Lisa A
name: Brenton, James
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Profiling breast cancer with expression arrays has become common, and it has been suggested
that the results from early studies will lead to understanding of the molecular differences
between clinical cases and allow individualization of care. We critically review two main
applications of expression profiling; studies unraveling novel breast cancer classifications and
those that aim to identify novel markers for prediction of clinical outcome. Breast cancer may
now be subclassified into luminal, basal, and HER2 subtypes with distinct differences in prognosis
and response to therapy. However, profiling studies to identify predictive markers have
suffered from methodologic problems that prevent general application of their results. Future
work will need to reanalyze existing microarray data sets to identify more representative sets
of candidate genes for use as prognostic signatures and will need to take into account the
new knowledge of molecular subtypes of breast cancer when assessing predictive effects.
Surface Recombination Limited Lifetimes of Photoexcited Carriers in Few-Layer Transition Metal Dichalcogenide MoS2
Creators: name: Wang, Haining
name: Zhang, Changjian
name: Rana, Farhan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present results on photoexcited carrier lifetimes in few-layer transition metal dichalcogenide MoS2 using nondegenerate ultrafast optical pump-probe technique. Our results show a sharp increase of the carrier lifetimes with the number of layers in the sample. Carrier lifetimes increase from few tens of picoseconds in monolayer samples to more than a nanosecond in 10-layer samples. The inverse carrier lifetime was found to scale according to the probability of the carriers being present at the surface layers, as given by the carrier wavefunction in few layer samples, which can be treated as quantum wells. The carrier lifetimes were found to be largely independent of the temperature and the inverse carrier lifetimes scaled linearly with the photoexcited carrier density. These observations are consistent with defect-assisted carrier recombination, in which the capture of electrons and holes by defects occurs via Auger scatterings. Our results suggest that carrier lifetimes in few-layer samples are surface recombination limited due to the much larger defect densities at the surface layers compared to the inner layers.
description: 19 pages, 5 figures, supplementary information at the end
A Generalized Double Chaplygin Model for Anisotropic Matter: The Newtonian Case
Creators: name: Abellán, Gabriel
name: Rincon, Angel
name: Sanchez, Eduard
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this work, we investigate astrophysical systems in a Newtonian regime using anisotropic matter. For this purpose, we considered that both radial and tangential pressures satisfy a generalized Chaplygin-type equation of state. Using this model, we found the Lane--Emden equation for this system and solved it numerically for several sets of parameters. Finally, we explored the mass supported by this physical system and compared it with the Chandrasekhar mass.
description: 14 pages, 3 figures. Matches the published version (invited contribution to the Journal Universe)
Late Jurassic – Early Cretaceous marine deoxygenation in Northeast Greenland
Creators: name: Hovikoski, J.
name: Olivarius, M.
name: Bojesen-Koefoed, J. A.
name: Piasecki, S.
name: Alsen, P.
name: Fyhn, M. B. W.
name: Sharp, I.
name: Bjerager, M.
name: Vosgerau, H.
name: Lindström, S.
name: Bjerrum, C.
name: Ineson, J.
Publisher: name: Geological Society of London
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: S1: Facies table.
title: Integration of domestic ventilation systems with vertical axis wind turbine ventilation technology
Creators: name: Sitthipuk, Jirayut James
Publisher: name: Edinburgh Napier University
publisherIdentifier: https://ror.org/03zjvnn91
publisherIdentifierScheme: ROR
Year: 2024

description: The integration of natural ventilation components has become increasingly desirable in the building sector as a means to enhance ventilation systems. Low carbon technologies, such as windcatchers and turbine ventilators, are commonly employed in commercial, educational, and industrial buildings for cooling and ventilation purpose. This study investigates a novel concept of home ventilation systems integrated with a vertical axis wind turbine, aiming to provide a detailed understanding of the system’s ventilation performance concerning both air extraction and supply using a turbine ventilator.
Performing Computational Fluid Dynamics (CFD) simulations, the 8-blade turbine ventilator achieved a maximum exhaust flow rate of 87.52 l/s at a wind speed of 6 m/s, exceeding the minimum ventilation rate. Additionally, the initial design of the air intake vent (AIV) was tested, resulting in a maximum air supply flow rate of 38.25 l/s at 6 m/s. Subsequent modifications to the AIV were made, yielding two variants: AIV1 and AIV2, which improved ventilation performance by 5% and 20% respectively.
Given that the proposed turbine ventilator is in its initial design phase, the numerical results demonstrate promising potential of the development of a home ventilation system integrated with the turbine ventilator. This study serves as a foundation for further research and optimisation of such systems.
Late Jurassic – Early Cretaceous marine deoxygenation in Northeast Greenland
Creators: name: Hovikoski, J.
name: Olivarius, M.
name: Bojesen-Koefoed, J. A.
name: Piasecki, S.
name: Alsen, P.
name: Fyhn, M. B. W.
name: Sharp, I.
name: Bjerager, M.
name: Vosgerau, H.
name: Lindström, S.
name: Bjerrum, C.
name: Ineson, J.
Publisher: name: Geological Society of London
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: S4: Sedimentological log from Store Koldewey.
AdS (in)stability: an analytic approach
Creators: name: Craps, Ben
name: Evnin, Oleg
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We briefly review the topic of AdS (in)stability, mainly focusing on a recently introduced analytic approach and its interplay with numerical results.
description: 14 pages, based in part on an invited talk at the Leuven workshop on The String Theory Universe, September 7-11, 2015; v2: minor clarifications and references added
Culture and Spatial Frequency Impact Perceptual and Attentional ERP components
Creators: name: Lin, Tong
name: Gutchess, Angela
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: cultures
subject: ERP
subject: P3 component

description: In this study, we used EEG and Gabor patches of different spatial frequencies to investigate how individuals with distinct cultural backgrounds differ in the processing of lower versus higher spatial frequency information. Stimuli were Gabor patches of 4-degree angular size, with spatial frequencies ranging from 0.5 cycle per degree to 4 cpd. Participants fixated centrally, and Gabor patches were presented on either the left or right side of the screen for 100ms. To ensure participants were on task, participants were instructed to use peripheral vision to monitor onset of an intermittent red dot slightly below the fixation cross, and to press a button as soon as it appeared. We will test the effects of spatial frequency (LSF, HSF) and cultural background (Easterners, Westerners) in a 2 x 2 ANOVA. We hypothesize that Americans will prioritize HSF information and East Asians will prioritize LSF information. This may be reflected in ERP components related to perception (P1, N1) and expectation (P3).
Phase II Trial of Lapatinib for Brain Metastases in Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
Creators: name: Bullitt, Elizabeth
name: Come, Steven E.
name: Younger, Jerry
name: Crawford, Ann
name: Carey, Lisa A.
name: Hochberg, Fred
name: Winer, Eric P.
name: Lin, Nancy U.
name: Henson, John W.
name: Liu, Minetta C.
name: Kasparian, Elizabeth
name: Ewend, Matthew
name: Harris, Gordon J.
name: Kirsch, David G.
name: Gelman, Rebecca
name: Li, Xiaochun
name: Burstein, Harold J.
name: Van Den Abbeele, Annick D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Purpose: One third of women with advanced human epidermal growth factor receptor 2 (HER-2)–positive
breast cancer develop brain metastases; a subset progress in the CNS despite standard
approaches. Medical therapies for refractory brain metastases are neither well-studied nor
established. We evaluated the safety and efficacy of lapatinib, an oral inhibitor of epidermal growth
factor receptor (EGFR) and HER-2, in patients with HER-2–positive brain metastases.
Patients and Methods: Patients had HER-2–positive breast cancer, progressive brain metastases, prior trastuzumab
treatment, and at least one measurable metastatic brain lesion. Patients received lapatinib 750 mg
orally twice a day. Tumor response was assessed by magnetic resonance imaging every 8 weeks.
The primary end point was objective response (complete response [CR] plus partial response [PR])
in the CNS by Response Evaluation Criteria in Solid Tumors (RECIST). Secondary end points
included objective response in non-CNS sites, time to progression, overall survival, and toxicity.
Results: Thirty-nine patients were enrolled. All patients had developed brain metastases while receiving
trastuzumab; 37 had progressed after prior radiation. One patient achieved a PR in the brain by
RECIST (objective response rate 2.6%, 95% conditional CI, 0.21% to 26%). Seven patients (18%)
were progression free in both CNS and non-CNS sites at 16 weeks. Exploratory analyses identified
additional patients with some degree of volumetric reduction in brain tumor burden. The most
common adverse events (AEs) were diarrhea (grade 3, 21%) and fatigue (grade 3, 15%).
Conclusion: The study did not meet the predefined criteria for antitumor activity in highly refractory patients
with HER-2–positive brain metastases. Because of the volumetric changes observed in our
exploratory analysis, further studies are underway utilizing volumetric changes as a primary end
point.
Stress mindsets and mental health pre- and post-COVID-19
Creators: name: Yeager, David
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: Analysis will assess whether the stress mindsets are differentially predictive of coping in light of COVID-19. This will help address questions about the generalizability and applicability of past research on stress and coping in the current crisis.
Causation entropy from symbolic representations of dynamical systems
Creators: name: Cafaro, Carlo
name: Lord, Warren M.
name: Sun, Jie
name: Bollt, Erik M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences

description: Identification of causal structures and quantification of direct information flows in complex systems is a challenging yet important task, with practical applications in many fields. Data generated by dynamical processes or large-scale systems are often symbolized, either because of the finite resolution of the measurement apparatus, or because of the need of statistical estimation. By algorithmic application of causation entropy, we investigated the effects of symbolization on important concepts such as Markov order and causal structure of the tent map. We uncovered that these quantities depend nonmontonically and, most of all, sensitively on the choice of symbolization. Indeed, we show that Markov order and causal structure do not necessarily converge to their original analog counterparts as the resolution of the partitioning becomes finer.
description: 22 pages, 8 figures
title: The Utility of CT Metal Artifact Reduction Techniques in the Post Operative Assessment of a Novel Tantalum Intervertebral Spacer Device - An in Vitro Study.
Creators: name: Macdonald, Mark
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2015
Subjects: subject: Musculoskeletal spine
subject: CT
subject: Imaging sequences
subject: Artifacts

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: A concern in the use of metallic spine fusion devices is the ability to assess local bone and soft tissue structures on imaging. Computed tomography (CT) plays an important role in the post operative evaluation of patients suspected of having metal...
Impact of the Addition of Carboplatin and/or Bevacizumab to Neoadjuvant Once-per-Week Paclitaxel Followed by Dose-Dense Doxorubicin and Cyclophosphamide on Pathologic Complete Response Rates in Stage II to III Triple-Negative Breast Cancer: CALGB 40603 (Alliance)
Creators: name: Berry, Donald A.
name: Collyar, Deborah
name: Tolaney, Sara M.
name: Port, Elisa R.
name: Singh, Baljit
name: Carey, Lisa A.
name: Kuzma, Charles, S.
name: Hudis, Clifford A.
name: Somlo, George
name: Cirrincione, Constance T.
name: Golshan, Mehra
name: Sikov, William M.
name: Hahn, Olwen M.
name: Bellon, Jennifer R.
name: Winer, Eric P.
name: Pluard, Timothy J.
name: Perou, Charles M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Purpose: One third of patients with triple-negative breast cancer (TNBC) achieve pathologic complete response (pCR)
with standard neoadjuvant chemotherapy (NACT). CALGB 40603 (Alliance), a 2 x 2 factorial, open-label,
randomized phase II trial, evaluated the impact of adding carboplatin and/or bevacizumab.
Patients and Methods: 
Patients (N = 443) with stage II to III TNBC received paclitaxel 80 mg/m2 once per week (wP) for 12 weeks,
followed by doxorubicin plus cyclophosphamide once every 2 weeks (ddAC) for four cycles, and were
randomly assigned to concurrent carboplatin (area under curve 6) once every 3 weeks for four cycles and/or
bevacizumab 10 mg/kg once every 2 weeks for nine cycles. Effects of adding these agents on pCR breast
(ypT0/is), pCR breast/axilla (ypT0/isN0), treatment delivery, and toxicities were analyzed.
Results:
Patients assigned to either carboplatin or bevacizumab were less likely to complete wP and ddAC without
skipped doses, dose modification, or early discontinuation resulting from toxicity. Grade 3 neutropenia
and thrombocytopenia were more common with carboplatin, as were hypertension, infection, thromboembolic
events, bleeding, and postoperative complications with bevacizumab. Employing one-sided P
values, addition of either carboplatin (60% v 44%; P  .0018) or bevacizumab (59% v 48%; P =.0089)
significantly increased pCR breast, whereas only carboplatin (54% v 41%; P = .0029) significantly raised
pCR breast/axilla. More-than-additive interactions between the two agents could not be demonstrated.
Conclusion: In stage II to III TNBC, addition of either carboplatin or bevacizumab to NACT increased pCR rates,
but whether this will improve relapse-free or overall survival is unknown. Given results from
recently reported adjuvant trials, further investigation of bevacizumab in this setting is unlikely, but
the role of carboplatin could be evaluated in definitive studies, ideally limited to biologically defined
patient subsets most likely to benefit from this agent.
Learning from Negative User Feedback and Measuring Responsiveness for Sequential Recommenders
Creators: name: Wang, Yueqi
name: Halpern, Yoni
name: Chang, Shuo
name: Feng, Jingchen
name: Le, Elaine Ya
name: Li, Longfei
name: Liang, Xujian
name: Huang, Min-Cheng
name: Li, Shane
name: Beutel, Alex
name: Zhang, Yaping
name: Bi, Shuchao
Publisher: name: arXiv
Year: 2023
Subjects: subject: Information Retrieval (cs.IR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Sequential recommenders have been widely used in industry due to their strength in modeling user preferences. While these models excel at learning a user's positive interests, less attention has been paid to learning from negative user feedback. Negative user feedback is an important lever of user control, and comes with an expectation that recommenders should respond quickly and reduce similar recommendations to the user. However, negative feedback signals are often ignored in the training objective of sequential retrieval models, which primarily aim at predicting positive user interactions. In this work, we incorporate explicit and implicit negative user feedback into the training objective of sequential recommenders in the retrieval stage using a "not-to-recommend" loss function that optimizes for the log-likelihood of not recommending items with negative feedback. We demonstrate the effectiveness of this approach using live experiments on a large-scale industrial recommender system. Furthermore, we address a challenge in measuring recommender responsiveness to negative feedback by developing a counterfactual simulation framework to compare recommender responses between different user actions, showing improved responsiveness from the modeling change.
description: RecSys 2023 Industry Track
Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study
Creators: name: Cheang, Maggie C.U.
name: Perou, Charles M.
name: Troester, Melissa
name: Carey, Lisa A.
name: Millikan, Robert C.
name: Livasy, Chad A.
name: Dressler, Lynn
name: Earp, H. Shelton
name: Nielsen, Torsten
name: Deming, Sandra L.
name: Tse, Chiu Kit
name: Karaca, Gamze
name: Moorman, Patricia G.
name: Geradts, Joseph
name: Conway, Kathleen
name: Edmiston, Sharon
name: Cowan, David
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Context: Gene expression analysis has identified several breast cancer subtypes, including
basal-like, human epidermal growth factor receptor-2 positive/estrogen receptor
negative (HER2+/ER–), luminal A, and luminal B.
Objectives: To determine population-based distributions and clinical associations for
breast cancer subtypes.
Design, Setting, and Participants: Immunohistochemical surrogates for each subtype
were applied to 496 incident cases of invasive breast cancer from the Carolina
Breast Cancer Study (ascertained between May 1993 and December 1996), a population based,
case-control study that oversampled premenopausal and African American
women. Subtype definitions were as follows: luminal A (ER+ and/or progesterone receptor
positive [PR+], HER2−), luminal B (ER+ and/or PR+, HER2+), basal-like (ER−,
PR−, HER2−, cytokeratin 5/6 positive, and/or HER1+), HER2+/ER− (ER−, PR−, and
HER2+), and unclassified (negative for all 5 markers).
Main Outcome Measures: We examined the prevalence of breast cancer subtypes
within racial and menopausal subsets and determined their associations with tumor
size, axillary nodal status, mitotic index, nuclear pleomorphism, combined grade,
p53 mutation status, and breast cancer–specific survival.
Results The basal-like breast cancer subtype was more prevalent among premenopausal
African American women (39%) compared with postmenopausal African
American women (14%) and non–African American women (16%) of any age
(P<.001), whereas the luminal A subtype was less prevalent (36% vs 59% and
54%, respectively). The HER2+/ER− subtype did not vary with race or menopausal
status (6%-9%). Compared with luminal A, basal-like tumors had more TP53
mutations (44% vs 15%, P<.001), higher mitotic index (odds ratio [OR], 11.0;
95% confidence interval [CI], 5.6-21.7), more marked nuclear pleomorphism (OR,
9.7; 95% CI, 5.3-18.0), and higher combined grade (OR, 8.3; 95% CI, 4.4-15.6).
Breast cancer–specific survival differed by subtype (P<.001), with shortest survival
among HER2+/ER− and basal-like subtypes.
Conclusions: Basal-like breast tumors occurred at a higher prevalence among premenopausal
African American patients compared with postmenopausal African
American and non–African American patients in this population-based study. A
higher prevalence of basal-like breast tumors and a lower prevalence of luminal A
tumors could contribute to the poor prognosis of young African American women
with breast cancer.
Late Jurassic – Early Cretaceous marine deoxygenation in Northeast Greenland
Creators: name: Hovikoski, J.
name: Olivarius, M.
name: Bojesen-Koefoed, J. A.
name: Piasecki, S.
name: Alsen, P.
name: Fyhn, M. B. W.
name: Sharp, I.
name: Bjerager, M.
name: Vosgerau, H.
name: Lindström, S.
name: Bjerrum, C.
name: Ineson, J.
Publisher: name: Geological Society of London
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: S2: Summary of geochemistry data.
Implementing online blogging in EFL process-genre writing classes: exploring perceptions and attitudes of undergraduate learners of English in Saudi Arabia
Creators: name: Alenezi, Sultan Samah A
Publisher: name: University of Limerick
Year: 2023
Subjects: Language, communication and culture

description: Employing technology in enhancing language learning has been the concern of many researchers in the past twenty years. Specifically related to this thesis, blogs are claimed to act as an effective tool to develop EFL students’ writing skills, because the blog has the potential to provide students with an opportunity to practise writing in a tension-free environment and at their own pace when used outside of the classroom context (Lee, 2010; Sanjaya et al.,2020). However, little is known about its use in Saudi EFL writing classes. The present study, therefore, aimed to explore the effect of using online blogging on Saudi EFL students’ writing skills in one Saudi University. The study adopted a mixed design (quantitative and qualitative) to explore EFL students’ attitudes and perceptions about the effect of the use of such a technology in an EFL writing course. Following a teaching intervention involving the integration of blog writing,questionnaires and interviews were used to gather data from the student participants as part of this study. Both tools were integrated into action research to represent EFL students’ experiences in learning EFL writing using online blogging. A blog that was created for the purpose of the study was integrated through the learning management system Blackboard. The participants in the study were 30 second-year learners majoring in English who were registered in the academic writing course. The students were invited to complete a background profile questionnaire in the first week of their study, do specific writing tasks via blogging over a 12-week period, and finally complete the attitude questionnaires and take part in follow-up interviews after the course was over. The data gathered were analysed quantitatively and qualitatively. The results illustrate that, generally, learners showed positive perceptions and attitudes towards the blogging approach in EFL writing classes because they perceived that it provided them with many valuable opportunities that helped them to improve their writing skills. However, they also faced some challenges while blogging, which fall into two categories: learners’ skills-related challenges and technology-related challenges. These results are hoped to provide more insights into understanding the relationship between language learning through writing skills development and the use of technology through implementing blogging. Finally, the study provides significant recommendations for EFL writing teachers, the institution in which the study was conducted and other Saudi institutions, as well as other stakeholders involved in the development of EFL learners’ writing skills and the use of technology.
Detection of non-self-correcting nature of information cascade
Creators: name: Mori, Shintaro
name: Hino, Masafumi
name: Hisakado, Masato
name: Takahashi, Taiki
Publisher: name: arXiv
Year: 2015
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences

description: We propose a method of detecting non-self-correcting information cascades in experiments in which subjects choose an option sequentially by observing the choices of previous subjects. The method uses the correlation function $C(t)$ between the first and the $t+1$-th subject's choices. $C(t)$ measures the strength of the domino effect, and the limit value $c\equiv \lim_{t\to \infty}C(t)$ determines whether the domino effect lasts forever $(c>0)$ or not $(c=0)$. The condition $c>0$ is an adequate condition for a non-self-correcting system, and the probability that the majority's choice remains wrong in the limit $t\to \infty$ is positive. We apply the method to data from two experiments in which $T$ subjects answered two-choice questions: (i) general knowledge questions ($T_{avg}=60$) and (ii) urn-choice questions ($T=63$). We find $c>0$ for difficult questions in (i) and all cases in (ii), and the systems are not self-correcting.
description: 10 pages, 4 figures
Genetic heterogeneity of diffuse large B-cell lymphoma
Creators: name: Mann, Karen P.
name: Grubor, Vladimir
name: Richards, Kristy L.
name: Johnson, Amy J.
name: Ni, Ting
name: Banerjee, Anjishnu
name: Walsh, Katherine
name: Bernal-Mizrachi, Leon
name: Rizzieri, David A.
name: Mieczkowski, Piotr A.
name: Liu, Qingquan
name: Evens, Andrew
name: Zhang, Jenny
name: Dave, Sandeep
name: Au, Wing Yan
name: Lugar, Patricia L.
name: Flowers, Christopher
name: Fan, Alice
name: Zhu, Jun
name: Luftig, Micah A.
name: Lagoo, Anand S.
name: Jima, Dereje
name: Byrd, John C.
name: Smith, Lisa
name: Dunson, David
name: Levy, Shawn
name: Gordon, Leo I.
name: Dunphy, Cherie
name: Chadburn, Amy
name: Choi, William
name: Gill, Javed I.
name: Love, Cassandra
name: Srivastava, Gopesh
name: Naresh, Kikkeri
name: Czader, Magdalena
name: Hsi, Eric D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Diffuse large B-cell lymphoma (DLBCL) is the most common form
of lymphoma in adults. The disease exhibits a striking heterogeneity
in gene expression profiles and clinical outcomes, but its
genetic causes remain to be fully defined. Through whole genome
and exome sequencing, we characterized the genetic diversity of
DLBCL. In all, we sequenced 73 DLBCL primary tumors (34 with
matched normal DNA). Separately, we sequenced the exomes of
21 DLBCL cell lines. We identified 322 DLBCL cancer genes that
were recurrently mutated in primary DLBCLs. We identified recurrent
mutations implicating a number of known and not previously
identified genes and pathways in DLBCL including those related to
chromatin modification (ARID1A and MEF2B), NF-κB (CARD11 and
TNFAIP3), PI3 kinase (PIK3CD, PIK3R1, and MTOR), B-cell lineage
(IRF8, POU2F2, and GNA13), and WNT signaling (WIF1). We also
experimentally validated a mutation in PIK3CD, a gene not previously
implicated in lymphomas. The patterns of mutation demonstrated
a classic long tail distribution with substantial variation
of mutated genes from patient to patient and also between published
studies. Thus, our study reveals the tremendous genetic
heterogeneity that underlies lymphomas and highlights the need
for personalized medicine approaches to treating these patients.
On Orbit Spaces of Distributive Binary $G$-Spaces
Creators: name: Gevorgyan, Pavel S.
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Topology (math.GN)
subject: FOS: Mathematics
subject: 54H15, 57S99

description: The orbit space of a distributive binary $G$-space is studied. A number of its properties in the case of a compact binarily acting group $G$ are established.
description: 7 pages
title: Outcomes of Asian Patients with Localised Prostate Cancer Treated With Combined Intensity Modulated Radiation Therapy and High Dose Rate Brachytherapy - A Single Institution Experience
Creators: name: Ng, Weishan Ivy
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2015
Subjects: subject: Pelvis
subject: Genital / Reproductive system male
subject: Oncology
subject: CT
subject: Brachytherapy
subject: Radiation therapy / Oncology
subject: Neoplasia
subject: Outcomes
subject: Toxicity

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Prostate cancer is on the rise in South-East Asia. However, available resources and acesss to radiotherapy are limited. This study aims to assess the feasibility and safety of implementing the American Brachytherapy Society (ABS) task group...
Enhancement of Two-photon Absorption in Quantum Wells for Extremely Nondegenerate Photon Pairs
Creators: name: Pattanaik, Himansu S.
name: Reichert, Matthew
name: Khurgin, Jacob B.
name: Hagan, David J.
name: Van Stryland, Eric W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We recently demonstrated orders of magnitude enhancement of two-photon absorption (2PA) in direct gap semiconductors due to intermediate state resonance enhancement for photons of very different energies. It can be expected that further enhancement of nondegenerate 2PA will be observed in quantum wells (QWs) since the intraband matrix elements do not vanish near the band center as they do in the bulk, and the density of states in QWs is larger near the band edge. Here we present a perturbation-theory based theoretical description of nondegenerate 2PA in semiconductor QWs, where both frequency and polarization of two incident waves can vary independently. Analytical expressions for all possible permutations of frequencies and polarizations have been obtained, and the results are compared with degenerate 2PA in quantum wells along with degenerate and nondegenerate 2PA in bulk semiconductors. We show that using QWs in place of bulk semiconductors with both beams in the TM-polarized mode leads to an additional order of magnitude increase in the nondegenerate 2PA. Explicit calculations for GaAs QWs are presented.
description: 24 pages, 13 figures
Weak Measurements, Quantum State Collapse and the Born Rule
Creators: name: Patel, Apoorva
name: Kumar, Parveen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Projective measurement is used as a fundamental axiom in quantum mechanics, even though it is discontinuous and cannot predict which measured operator eigenstate will be observed in which experimental run. The probabilistic Born rule gives it an ensemble interpretation, predicting proportions of various outcomes over many experimental runs. Understanding gradual weak measurements requires replacing this scenario with a dynamical evolution equation for the collapse of the quantum state in individual experimental runs. We revisit the quantum trajectory framework that models quantum measurement as a continuous nonlinear stochastic process. We describe the ensemble of quantum trajectories as noise fluctuations on top of geodesics that attract the quantum state towards the measured operator eigenstates. Investigation of the restrictions needed on the ensemble of quantum trajectories, so as to reproduce projective measurement in the appropriate limit, shows that the Born rule follows when the magnitudes of the noise and the attraction are precisely related, in a manner reminiscent of the fluctuation-dissipation relation. That implies that both the noise and the attraction have a common origin in the measurement interaction between the system and the apparatus. We analyse the quantum trajectory ensemble for the scenarios of quantum diffusion and binary quantum jump, and show that the ensemble distribution is completely determined in terms of a single evolution parameter. This trajectory ensemble distribution can be tested in weak measurement experiments. We also comment on how the required noise may arise in the measuring apparatus.
description: Revtex, 11 pages, 4 figures. Some text overlap with arXiv:1412.1312 (v2) Substantially revised, duly acknowledging similar results obtained by Nicolas Gisin thirty years ago. (v3) Expanded and rewritten to include analysis of shot noise and fluctuation-dissipation relation (v4) Final version
Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 63, Nr. 2 (1985)
Creators: name: Germania : Anzeiger Der Römisch-Germanischen Kommission Des Deutschen Archäologischen Instituts
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2019

description: Titelei
Klaus Schwarz. In memoriam
Inhalt
Die Entwicklung des weiblichen Trachtzubehörs während der Hallstattzeit der Schweiz...401-437
José María Blázquez, Francisco Presedo, Francisco Javier Lomas y Javier Fernández Nieto, Protohistoria. Historia de España Antigua I...572-578
Gerión. Band 1, 1983. Herausgegeben von J. M. Blázquez Martínez...582
Pollentia 3, Estudios de los materiales, 1. Sa Portella. Excavaciones 1957—1963. Par A. Arribas, E. Ettlinger, M. Fernandez-Miranda, J. Llabres, E. Manera, G. Martin et H. B. Mattingly...583-584
Progrès récentes dans l’Étude du Néolithique Ancien. Actes du Colloque International organisé à Gand les 21 et 22 Mai 1982. Publiés par Sigfried J. de Laet...547-549
Weitere hagiographische Texte und amtliches Schriftgut. Übersetzt von Camilla Dirlmeier, durchgesehen und mit Anmerkungen versehen von Klaus Sprigade...604-605
Verfasserverzeichnis der Bibliothekszugänge in Germania 63, 1985...689-721
Thomas Arzt/Roland Dollinger/Maria Hippius.Gräfin Dürckheim (Hg.), Philosophia Naturalis - Beiträge zu einer zeitgemäßen Naturphilosophie
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 51 Nr. 11 (1997): Herder Korrespondenz, Band 51, Heft 11
T. ROOD & M. TAMIOLAKI, Xenophon's Anabasis and its Reception, Trends in Classics, Supplementary Volumes 134. Walter de Gruyter GmbH & Co, Berlin & Boston, 2022, xvi+556 s. ISBN: 9783110793376
Creators: name: Yarlıgaş, Oğuz
Publisher: name: Zenodo
Year: 2023

description: Book Notice.
ARCADIA: State of the art of the technologiesstate, design, implementation and evaluation of the proposed prototype
Creators: name: ITI, Instituto Tecnológico de Informática
Publisher: name: Zenodo
Year: 2023
Subjects: arcadia
2022
gamification
serious games
extended reality
mental health
augmented reality

description: ARCADIA (Extended Reality for Mental Health and Wellbeing based on Gamification and Serious Games) is a project funded by the Instituto Valenciano de Competitividad Empresarial (IVACE) and the European Union through the European Regional Development Fund (ERDF). 

The ARCADIA project aims to design and develop gamified experiences and serious games for Mixed Reality environments, oriented to the improvement of mental health and well-being. These immersive experiences are focused as a complement or accompaniment to therapy, where the use of game-based strategies allows to increase the benefits of these systems.

This paper summarizes the state of the art of the technologies involved, as well as the design, implementation and evaluation of the proposed prototype.
description: ARCADIA. Project funded by the Valencian Institute of Business Competitiveness (IVACE) and European Union through the European Regional Development Fund (ERDF), within the public grant program adressed to Technological Institutes of the Valencian Community for the development of non-economic R&D projects carried out in cooperation with companies during 2022 with 233.493,91 €. File number: IMDEEA/2022/22
MapSplice: Accurate mapping of RNA-seq reads for splice junction discovery
Creators: name: Chiang, Derek Y.
name: Zeng, Zheng
name: Mieczkowski, Piotr
name: Singh, Darshan
name: Liu, Jinze
name: Prins, Jan F.
name: MacLeod, James N.
name: Huang, Yan
name: Wang, Kai
name: Coleman, Stephen J.
name: He, Xiaping
name: Savich, Gleb L.
name: Grimm, Sara A.
name: Perou, Charles A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The accurate mapping of reads that span splice
junctions is a critical component of all analytic techniques
that work with RNA-seq data. We introduce a
second generation splice detection algorithm,
MapSplice, whose focus is high sensitivity and specificity
in the detection of splices as well as CPU and
memory efficiency. MapSplice can be applied to
both short (<75 bp) and long reads (>75 bp).
MapSplice is not dependent on splice site features
or intron length, consequently it can detect novel
canonical as well as non-canonical splices.
MapSplice leverages the quality and diversity of
read alignments of a given splice to increase
accuracy. We demonstrate that MapSplice
achieves higher sensitivity and specificity than
TopHat and SpliceMap on a set of simulated
RNA-seq data. Experimental studies also support
the accuracy of the algorithm. Splice junctions
derived from eight breast cancer RNA-seq
datasets recapitulated the extensiveness of alternative
splicing on a global level as well as the differences
between molecular subtypes of breast
cancer. These combined results indicate that
MapSplice is a highly accurate algorithm for the
alignment of RNA-seq reads to splice junctions.
Software download URL: http://www.netlab.uky
.edu/p/bioinfo/MapSplice.