cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Turbulence in thick fluid layers
Creators: name: Byrne, David John
Publisher: name: The Australian National University
Year: 2011
Subjects: subject: TA357.5.T87 B97 2011
subject: Turbulence
subject: Fluid dynamics

description: This thesis presents the experimental study of turbulence in fluid layers of finite depths i.e. away from the ideal quasi-2D approximation. The development and implementation of a two colour Particle Image Velocimetry/Particle Tracking hybrid is presented along with a defocused PIV diagnostic for measuring full 3D components of the velocity field. A parametric study in electromagnetically driven flows in a single and double layer configuration is presented. It is shown that as the layer depth increases there is an onset of 3D motion within the layer. Surprisingly, despite there being a substantial 3D component in the flow, the inverse energy cascade is still present. In low Reynolds number flows, a direct 3D energy cascade cannot be supported and as a result, the transition to a more 3D flow only has the effect of increasing dissipation in the system compared to that associated with quasi two-dimensional flows. The study of the vertical structure of the velocities reveals that, due to the boundary conditions of the free surface and bottom boundary, there are regions of the layer that remain 2D and that 3D motions are most prominent in the mid-layer. This leads to a difference in dissipation throughout the layer and thus the largest scale that the inverse cascade can sustain changes in the different regions of the flow. If the damping is low enough for the condensation of energy to begin, the large structure formed near the surface, may begin to affect the underlying 3D motions.
Additional file 1 of Structure‐based identification of dual ligands at the A2AR and PDE10A with anti‐proliferative effects in lung cancer cell‐lines
Creators: name: Kalash, Leen
name: Winfield, Ian
name: Safitri, Dewi
name: Bermudez, Marcel
name: Carvalho, Sabrina
name: Glen, Robert
name: Ladds, Graham
name: Bender, Andreas
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Plant Biology

description: Additional file 1. Discussion. Additional figures and tables
Questioning the existence of a unique ground state structure for Si clusters
Creators: name: Hellmann, W.
name: Hennig, R.
name: Goedecker, S.
name: Umrigar, C.
name: Delley, B.
name: Lenosky, T.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Density functional and quantum Monte Carlo calculations challenge the existence of a unique ground state structure for certain Si clusters. For Si clusters with more than a dozen atoms the lowest ten isomers are close in energy and for some clusters entropic effects can change the energetic ordering of the configurations. Isotope pure configurations with rotational symmetry and symmetric configurations containing one additional isotope are disfavored by these effects. Comparisons with experiment are thus difficult since a mixture of configurations is to be expected at thermal equilibrium.
The Weak Galerkin Finite Element Method for the Transport-Reaction Equation
Creators: name: Zhang, Tie
name: Zhang, Shangyou
Publisher: name: arXiv
Year: 2020
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We present and analyze a weak Galerkin finite element method for solving the transport-reaction equation in $d$ space dimensions. This method is highly flexible by allowing the use of discontinuous finite element on general meshes consisting of arbitrary polygon/polyhedra. We derive the \textcolor[rgb]{0.00,0.00,1.00}{$L_2$-error estimate} of $O(h^{k+\frac{1}{2}})$-order for the discrete solution when the $k$th-order polynomials are used for $k\geq 0$. Moreover, for a special class of meshes, we also obtain the \textcolor[rgb]{0.00,0.00,1.00}{optimal error} estimate of $O(h^{k+1})$-order in the $L_2$-norm. A derivative recovery formula is presented to approximate the convection \textcolor[rgb]{1.00,0.00,0.00}{directional derivative} and the corresponding superconvergence estimate is given. Numerical examples on compatible and non-compatible meshes are provided to show the effectiveness of this weak Galerkin method.
Risk factors for breast cancer subtypes by race and ethnicity: a scoping review
Creators: name: Gierach, Gretchen L
name: Ahearn, Thomas U
name: Roberts, Sylvia
name: Butera, Gisela
name: Franklin, Jamirra
name: Hurson, Amber N
name: Tamimi, Rulla M
name: Garcia-Closas, Montserrat
name: Harris, Alexandra R
name: Chang-Claude, Jenny
name: Jung, Audrey Y
name: Jenkins, Brittany D
name: Schmidt, Marjanka K
name: Koka, Hela
name: Yang, Xiaohong R
name: Troester, Melissa A
name: Keeman, Renske
name: Middha, Pooja
name: Bandera, Elisa V
name: Abubakar, Mustapha
name: Fan, Sharon
Publisher: name: Oxford University Press (OUP)
Year: 2024

description: BACKGROUND: Breast cancer is comprised of distinct molecular subtypes. Studies have reported differences in risk factor associations with breast cancer subtypes, especially by tumor estrogen receptor (ER) status, but their consistency across racial and ethnic populations has not been comprehensively evaluated.
METHODS: We conducted a qualitative, scoping literature review using the Preferred Reporting Items for Systematic Reviews and Meta-analysis, extension for Scoping Reviews to investigate consistencies in associations between 18 breast cancer risk factors (reproductive, anthropometric, lifestyle, and medical history) and risk of ER-defined subtypes in women who self-identify as Asian, Black or African American, Hispanic or Latina, or White. We reviewed publications between January 1, 1990 and July 1, 2022. Etiologic heterogeneity evidence (convincing, suggestive, none, or inconclusive) was determined by expert consensus.
RESULTS: Publications per risk factor ranged from 14 (benign breast disease history) to 66 (parity). Publications were most abundant for White women, followed by Asian, Black or African American, and Hispanic or Latina women. Etiologic heterogeneity evidence was strongest for parity, followed by age at first birth, post-menopausal BMI, oral contraceptive use, and estrogen-only and combined menopausal hormone therapy. Evidence was limited for other risk factors. Findings were consistent across racial and ethnic groups, although the strength of evidence varied.
CONCLUSION: The literature supports etiologic heterogeneity by ER for some established risk factors that are consistent across race and ethnicity groups. However, in non-White populations evidence is limited. Larger, more comparable data in diverse populations is needed to better characterize breast cancer etiologic heterogeneity.
Les passages initiatiques dans la littérature fantastique pour jeunes adultes
Creators: name: Cloutier, Kelly-Ann
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2024
Subjects: Passages
Initiation
Initiatique
Ethnocritique
Jeunes adultes
Littérature
Fantastique
Personnage liminaire

description: La thématique du passage occupe une place importante non seulement dans la tradition littéraire, mais aussi dans les études philosophiques, historiques et esthétiques. Souvent liée aux rites de passage, cette thématique fut un sujet d’études privilégié par le célèbre ethnologue Arnold Van Gennep. En effet, c’est en 1909 qu’il publie l’un de ses ouvrages majeurs intitulé Les rites de passages, dans lequel il mentionne qu’un passage est avant tout « un état de l’entre-deux  » (Van Gennep, 1909). Qu’arriverait-il si l’on analysait ces passages initiatiques d’un point de vue ethnocritique et qu’on approfondissait la réflexion en se concentrant sur la littérature fantastique pour jeunes adultes, une littérature qui par définition partage elle aussi cet état d’entre-deux ? Cette thèse de maîtrise en recherche-création explore les différentes représentations des passages dans la littérature fantastique pour jeunes adultes. On y retrouve trois parties. Tout d’abord, nous commençons avec des repères conceptuels. Nous définissons la littérature fantastique et observons ses principales caractéristiques. Ensuite, nous portons notre attention sur la littérature pour jeunes adultes en précisant ce que cette étiquette signifie : en quoi est-elle une littérature de l’entre-deux ? Nous poursuivons notre parcours en interrogeant les modalités de mise en texte des passages, des rites initiatiques et des personnages liminaires. Une fois la théorie présentée, nous employons celle-ci à l’analyse de deux romans fantastiques destinés aux jeunes adultes afin d’en mieux saisir le fonctionnement. La deuxième partie est consacrée à la création, qui prend la forme d’une première section d’un roman fantastique pour les jeunes adultes. Dans celle-ci, je tente d’appliquer les notions abordées dans la partie recherche, soit de créer un univers fantastique ainsi qu’une trame narrative adaptée aux thématiques récurrentes des romans pour jeunes adultes qui puisse permettre de bien représenter les passages initiatiques. En effet, mon personnage principal est le sujet d’une quête initiatique : il traverse différents passages et connaît des transformations, qui seront à l’origine d’une transition d’un statut à un autre. Finalement, cette thèse de maîtrise se termine par une troisième partie qui propose un retour sur l’écriture et sur le processus de création, questionnant des décisions prises dans la fiction à l’aune des travaux savants et vérifiant spécifiquement comment les moyens dénotés dans la portion consacrée à l’analyse littéraire de la première partie ont pu s’inscrire ou non dans le volet création.
A Study On Some Geometric and Physical Properties of Hyper-Generalised Quasi-Einstein Spacetime
Creators: name: Chattopadhyay, Kaushik
name: Bhattacharyya, Arindam
name: Debnath, Dipankar
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Differential Geometry (math.DG)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 53C15, 53C25, 53C35

description: In the present paper we discuss about a set of geometric and physical properties of hyper-generalised quasi-Einstein spacetime. At the beginning we discuss about pseudosymmetry over a hyper-generalised quasi-Einstein spacetime. Here we discuss about W2-Ricci pseudosymmetry, Z-Ricci pseudosymmetry, Ricci pseudosymmetry and projective pseudosymmetry over a hyper-generalised quasi-Einstein spacetime. Later on we take over Ricci symmetric hyper-generalised quasi-Einstein spacetime and derive a set of important geometric and physical theorems over it. Moving further we consider some physical applications of the hyper-generalised quasi-Einstein spacetime. Lastly we prove the existence of a hyper-generalised quasi-Einstein spacetime by constructing a non-trivial example.
Additional file 1 of The role of antimicrobial resistance on long-term mortality and quality of life in critically ill patients: a prospective longitudinal 2-year study
Creators: name: Koukoubani, Triantafyllia
name: Demosthenes Makris
name: Daniil, Zoe
name: Theoniki Paraforou
name: Tsolaki, Vasiliki
name: Epaminondas Zakynthinos
name: Papanikolaou, John
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1. Details in methodology used, results obtained.
Daughters with a parent in a care facility: a stress and coping model
Creators: name: Krause, Allison Mary
Publisher: name: University of British Columbia
Year: 2009

description: The purpose of this study was to test Lazarus and Folkman's (1984) theoretical framework of stress and coping as it applied to daughters who have parents living in care facilities. Specifically, the effects of personal and environmental influences, cognitive appraisals, and coping on positive affect and depression were examined in two subsamples of daughters: daughters with parents with dementia (n=100) and daughters with parents with other health difficulties (n=89). The data were collected from a volunteer sample of 189 daughters (M age 51.3) in the Greater Vancouver region. Daughters completed three parts of a questionnaire over a six-week period. Specific variables of interest included prior communal behaviors, support satisfaction, care satisfaction, appraisals (perceived control and perceived stress), coping strategies (relationship-focused, problem-focused, emotionfocused), positive affect, and depression. Negative affectivity (NA) was examined as a confounding variable. Path analysis using LISREL VIII (Joreskog & Sorbom, 1993) was undertaken to examine the hypothesized relationships between antecedent, mediating, and outcome variables that are central to Lazarus and Folkman's (1984) theoretical framework. Initial results revealed a poor fitting model for both the dementia and other health groups. However, a revised model, taking into account theoretical and empirical support for a direct relationship between support satisfaction and emotion-focused coping, provided an acceptable fit for both groups. The overall pattern of relationships for the variables in the model offer some support for the hypothesized model and for Lazarus and Folkman's theoretical assumptions. For both groups, greater control over the stressful aspect of facility care was related to more problem-focused coping, which in turn was related to more positive affect. For the other health group, greater appraised stress was related to more emotion-focused coping, which was in turn was related to greater depression. Among daughters with parents with dementia, low levels of care satisfaction and high communal behaviors were associated with greater perceived control. The hypothesized mediational role of appraisals and coping was not supported. The results point to the importance of understanding caregiving in the context of chronic stress and the unique contribution of personality, health type, and positive aspects of caregiving to a daughter's stress process.
Antiproton and proton collisions with the alkali metal atoms Li, Na, and K
Creators: name: Lühr, Armin
name: Saenz, Alejandro
Publisher: name: arXiv
Year: 2008
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Single-electron ionization and excitation cross sections as well as cross sections for excitation into the first excited p state of the alkali metal atoms Li(2s), Na(3s) and K(4s) colliding with antiprotons and protons were calculated using a time-dependent channel-coupling approach. For antiprotons an impact-energy range from 0.25 to 1000 keV and for protons from 2 to 1000 keV was considered. The target atoms are treated as effective one-electron systems using a model potential. The results are compared with theoretical and experimental data from literature and calculated cross sections for antiproton-hydrogen collisions. For proton collisions a good overall agreement is found which confirms the present numerical approach, whereas discrepancies are found between the present antiproton cross sections and those calculated by Stary et al., J.Phys.B 23, 263 (1990).
Additional file 1 of CRISPR/Cas9-mediated activation of NR5A1 steers female human embryonic stem cell-derived bipotential gonadal-like cells towards a steroidogenic cell fate
Creators: name: Danti, Laura
name: Lundin, Karolina
name: Sepponen, Kirsi
name: Yohannes, Dawit A.
name: Kere, Juha
name: Tuuri, Timo
name: Tapanainen, Juha S.
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Supplementary figure 1. Bulk RNA-sequencing analyses showed differences between the control (-DOX-TMP) and induced (+DOX+TMP) conditions. A. Principal component analysis (PCA) comparing samples from different days of differentiation and control (CTRL, -DOX –TMP) and induced (IND, +DOX +TMP) conditions. d; day. B. Flowchart comparing the number of differentially expressed (black), coding (orange), non-coding (blue), upregulated (green) and downregulated (red) genes in induced (+DOX+TMP) and non-induced (-DOX-TMP) conditions at different timepoints in both female and male gonadal differentiation. d; day. Supplementary figure 2. Differentially expressed upregulated genes were mostly associated with (adrenal) steroidogenesis. A. RT-qPCR analysis showed that NR5A1 induction upregulated the markers HPGD, GSTA1, GSTA2, WNT6, B4GALNT2 and GNRHR. Data are reported as mean ± SEM, n=3 biological replicates. Two-way ANOVA; 0.12 (ns), 0.033 (*), 0.002 (**), < 0.001 (***). d; day. B. Bar charts showing the correlated KEGG 2021 human pathways of the female DE genes between control (CTRL, -DOX -TMP) and induced (IND, +DOX +TMP) conditions at days 6, 8 and 10 of gonadal differentiation. The bar charts show the top 10 enriched terms in the chosen library, along with their corresponding p-values. Coloured bars correspond to terms with significant p-values (< 0.05). An asterisk (*) next to a p-value indicates the term also had a significant adjusted p-value (< 0.05). Supplementary figure 3. Adrenal, testicular, and ovarian steroidogenesis markers were upregulated upon NR5A1 induction. Comparison of the expression of RNA-sequenced non-induced (CTRL, -DOX-TMP) and induced (IND, +DOX+TMP) samples. Known adrenal, testicular and ovarian steroidogenic markers were upregulated upon NR5A1 induction. Each square represents the expression of a specific gene within a technical replicate. The intensity of gene expression is indicated by a colour scale based on row z-scores (red, highest expression levels; blue, lowest expression levels). d, day.
Fractional Ornstein-Uhlenbeck process with stochastic forcing and its applications
Creators: name: Ascione, Giacomo
name: Mishura, Yuliya
name: Pirozzi, Enrica
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60G22, 60G15, 68U20

description: We consider a fractional Ornstein-Uhlenbeck process involving a stochastic forcing term in the drift, as a solution of a linear stochastic differential equation driven by a fractional Brownian motion. For such process we specify mean and covariance functions, concentrating on their asymptotic behavior. This gives us a sort of short- or long-range dependence, under specified hypotheses on the covariance of the forcing process. Applications of this process in neuronal modeling are discussed, providing an example of a stochastic forcing term as a linear combination of Heaviside functions with random center. Simulation algorithms for the sample path of this process are finally given.
description: 29 pages, 14 figures
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer
Creators: name: Hibshman, Priya S.
name: Vonderheide, Robert H.
name: Sekulic, Miroslav
name: Manji, Gulam A.
name: Bakir, Basil
name: Muonio, Karl
name: Califano, Andrea
name: Hennessey, Connor
name: Chabot, John A.
name: Orlen, Margo
name: Dilly, Julien
name: Wei, Xing
name: Menard, Marie
name: Yang, Yu C.
name: Jiang, Lingyan
name: Lagana, Stephen M.
name: Socci, Nicholas D.
name: Wasko, Urszula N.
name: Jiang, Jingjing
name: Sastra, Stephen A.
name: Ronan, Melissa M.
name: Barker, Natalie K.
name: Stalnecker, Clint A.
name: Stanger, Ben Z.
name: Tian, Sha
name: Tsai, Kenneth Y.
name: Sor, Rina
name: Wang, Yingyun
name: Smith, Jacqueline A. M.
name: Herring, Laura E.
name: Palermo, Carmine F.
name: Kemp, Samantha B.
name: Curiel-Garcia, Alvaro
name: Roth, Jennifer A.
name: Rees, Matthew G.
name: Courtney, Haley
name: Baslan, Timour
name: Dalton, Tanner C.
name: Drizyte-Miller, Kristina
name: Gindin, Yevgeniy
name: Vostrejs, William P.
name: Clendenin, Cynthia
name: Decker-Farrell, Amanda R.
name: Aguirre, Andrew J.
name: Hasselluhn, Marie C.
name: Singh, Mallika
name: Edwards, A. Cole
name: Helland, Ciara
name: Badgley, Michael A.
name: Wildes, David
name: Wang, Junning
name: Zhao, Ruiping
name: Olive, Kenneth P.
name: Der, Channing J.
name: Quintana, Elsa
name: Wolpin, Brian M.
name: Tomassoni, Lorenzo
name: Holderfield, Matthew
name: Chang, Stephanie
name: Lee, Bianca
name: Brodbeck, Jens
name: Wang, Zhengping
name: Lowe, Scott W.
name: Kluger, Michael D.
name: Cleary, James M.
name: Amparo, Amber M.
Publisher: name: Springer Nature
Year: 2024

description: Broad-spectrum RAS inhibition has the potential to benefit roughly a quarter of human patients with cancer whose tumours are driven by RAS mutations1,2. RMC-7977 is a highly selective inhibitor of the active GTP-bound forms of KRAS, HRAS and NRAS, with affinity for both mutant and wild-type variants3. More than 90% of cases of human pancreatic ductal adenocarcinoma (PDAC) are driven by activating mutations in KRAS4. Here we assessed the therapeutic potential of RMC-7977 in a comprehensive range of PDAC models. We observed broad and pronounced anti-tumour activity across models following direct RAS inhibition at exposures that were well-tolerated in vivo. Pharmacological analyses revealed divergent responses to RMC-7977 in tumour versus normal tissues. Treated tumours exhibited waves of apoptosis along with sustained proliferative arrest, whereas normal tissues underwent only transient decreases in proliferation, with no evidence of apoptosis. In the autochthonous KPC mouse model, RMC-7977 treatment resulted in a profound extension of survival followed by on-treatment relapse. Analysis of relapsed tumours identified Myc copy number gain as a prevalent candidate resistance mechanism, which could be overcome by combinatorial TEAD inhibition in vitro. Together, these data establish a strong preclinical rationale for the use of broad-spectrum RAS-GTP inhibition in the setting of PDAC and identify a promising candidate combination therapeutic regimen to overcome monotherapy resistance.
Ανάπτυξη αγροτικού χώρου στο νομό Πέλλας:
Creators: name: Συμεωνίδου, Μαρία Ιωάννη
Publisher: name: Aristotle University of Thessaloniki
Year: 2009
Subjects: Ανάπτυξη υπαίθρου
Αγροτική ανάπτυξη
Νομός Πέλλας
Ανάλυση SWOT
Rural development
SWOT analysis
Prefecture of Pella

description: Η παρούσα εργασία μελετά μία συγκεκριμένη γεωγραφική ενότητα του Νομού Πέλλας και έχει ως σκοπό να αναδείξει εκείνα τα δυναμικά στοιχεία που διαθέτει έτσι ώστε να τη μετατρέψει σε σύγχρονο κέντρο αγροτικής παραγωγής και έρευνας με περιβάλλον υψηλής ποιότητας, καθώς και σε σημαντικό πόλο ανάπτυξης με πολιτισμικό, ιστορικό και αρχαιολογικό ενδιαφέρον. Το όραμα αυτό επιτυγχάνεται μέσα από τον καθορισμό εστιασμένων θεματικά γενικών και ειδικών στόχων και το σχεδιασμό συγκεκριμένων παρεμβάσεων, στοιχεία τα οποία εμφανίζουν υψηλό βαθμό συσχέτισης τόσο μεταξύ τους όσο και με το ευρύτερο εθνικό και Κοινοτικό αναπτυξιακό πλαίσιο που υιοθετείται για την περιοχή παρέμβασης. Συμπερασματικά, η στρατηγική ανάπτυξης που προτείνεται σε συνδυασμό με την αξιοποίηση των χαρακτηριστικών γνωρισμάτων της περιοχής παρέμβασης, δύναται να τη μετατρέψει σε σημαντικό κέντρο αγροτικής παραγωγής και επεξεργασίας αγροτικών προϊόντων, περιοχή με διαφοροποιημένη εμπορική δραστηριότητα και υψηλής ποιότητας περιβάλλοντος και διαβίωσης, καθώς και σε κύριο συστατικό ενός νέου σημαντικού πόλου ανάπτυξης της ευρύτερης περιοχής στον τομέα του τουρισμού, του πολιτισμού, της ιστορίας και της αναψυχής.
description: The present study on a specific geographic unit of Pella’s Prefecture aims to bring out the most dynamic features of the area, so as to transform it into a modern centre of agricultural production and research with high quality of life, as well as into an important development pole of cultural, historical and archaeological interest. This vision is achieved by the determination of thematically focused general and specific objectives and specific interventions. These elements are characterised by high correlation degree not only among them, but also with the broader National and European development framework, that is adopted in the intervention area. In conclusion, the development strategy that is being proposed, in combination with the exploitation of the study area’s characteristic traits, is able to transform this geographic unit of Pella into a significant centre of agricultural production and process of rural products, with differentiated commercial activities and high quality of environment and life, as well as in a vital component of a new important development pole of the broader area in the sector of tourism, culture, history and recreation.
Correlation between site preference of ternary Mn addition in LaAg and superconductivity
Creators: name: Kumar, S.
name: Kaul, S. N.
name: Fernandez, J. Rodriguez
name: Barquin, L. Fernandez
name: Henry, P. F.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The results of an extensive investigation of structure, surface morphology, composition and the superconducting-normal phase diagram of a new unconventional superconductor LaAg1-cMnc with nominal composition c = 0.0, 0.025, 0.05, 0.1, 0.2 and 0.3, reveal the following. The alloys with c = 0, 0.025 and 0.05 are essentially single phase alloys with the actual Mn concentration, x, same as the nominal one, i.e., c = x, whereas in the alloys with c = 0.1, 0.2 and 0.3, the actual Mn concentration of the majority phase (crystalline grains) is x = 0.050(1), 0.080(1) and 0.100(1), respectively. The ternary Mn addition does not alter the CsCl structure of the parent compound LaAg. Neither a structural phase transition occurs nor a long-range antiferromagnetic order exists at any temperature within the range 1.8K < = T < = 50K in any of the Mn containing alloys. Mn has exclusive La (Ag) site preference in the alloy (alloys) with x = c = 0.025 (x < = 0.05 or c < = 0.1) whereas in the alloy with x = c = 0.05, Mn has essentially no site preference in that all the Mn atoms either occupy the La sites or the Ag sites. In the alloys (alloy) with x < = 0.05 (x = c = 0.025), substitution of Ag (La) by Mn at the Ag (La) sub-lattice sites in LaAg host gives rise to unconventional superconductivity (destroys the conventional phonon-mediated superconductivity prevalent in the parent LaAg compound).
description: The manuscript has 25 pages that include the text, 2 Tables and 12 Figures. The manuscript contains unpublished results which are of paramount interest to the Condensed Matter Physics Community at large and particularly to those engaged in the pursuit of research in Unconventional Superconductivity
$λ$-Core Distance Partitions
Creators: name: Mifsud, Xandru
Publisher: name: arXiv
Year: 2020
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C50, 15A18

description: The $λ$-core vertices of a graph correspond to the non-zero entries of some eigenvector of $λ$ for a universal adjacency matrix $\mathbf{U}$ of the graph. We define a partition of the vertex set $V$ based on the $λ$-core vertex set and its neighbourhoods at a distance $r$, and give a number of results relating the structure of the graph to this partition. For such partitions, we also define an entropic measure for the information content of a graph, related to every distinct eigenvalue $λ$ of $\mathbf{U}$, and discuss its properties and potential applications.
description: 8 pages, 2 figures. Linear Algebra Appl. (2021)
Giant Optical Non-linearity induced by a Single Two-Level System interacting with a Cavity in the Purcell Regime
Creators: name: Auffeves-Garnier, Alexia
name: Simon, Christoph
name: Gerard, Jean-Michel
name: Poizat, Jean-Philippe
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A two-level system that is coupled to a high-finesse cavity in the Purcell regime exhibits a giant optical non-linearity due to the saturation of the two-level system at very low intensities, of the order of one photon per lifetime. We perform a detailed analysis of this effect, taking into account the most important practical imperfections. Our conclusion is that an experimental demonstration of the giant non-linearity should be feasible using semiconductor micropillar cavities containing a single quantum dot in resonance with the cavity mode.
description: 40 pages, 16 figures, accepted in Phys. Rev. A
The local appropriation of warrior ideals in Late Bronze Age Europe: a review of the rock art site of Arroyo Tamujoso 8 and the ‘warrior’ stela of Cancho Roano (Badajoz, Spain) [dataset]
Creators: name: Diaz-Guardamino, Marta
Publisher: name: Durham University
Year: 2022
Subjects: subject: Prehistoric peoples
subject: RTI
subject: Computational photography

description: Paper to be published in: Trabajos de Prehistoria https://tp.revistas.csic.es/index.php/tp/index
description: This study offers new insights into the local appropriation of warrior ideals in Late Bronze Age Europe. Through the new study of the carvings of Cancho Roano and Arroyo Tamujoso 8, located in Southwest Iberia and their landscape settings with state-of-the-art digital technologies, this paper unpicks some of the key idiosyncrasies of Iberian Late Bronze Age warrior iconography, revealing that responses to the warrior ideals circulating across Europe during that period were diverse. In order to understand the contexts of circulation and appropriation of these ideas from a local perspective, we also consider very briefly the multiscale connections in which the communities who created warrior stelae in Iberia were involved. The ultimate goal of this paper is to lay the groundwork for further work developing more detailed comparisons between Iberian warrior stelae and Swedish warrior iconography on rock art, also taking into account other evidence
Proactive corporate social responsibility and financial performance
Creators: name: Waedt, Holger
Publisher: name: The Australian National University
Year: 2010
Subjects: subject: HD60.W34 2010
subject: Social responsibility of business
subject: Corporations Finance.

description: In this study, I examine the dynamic relationship between proactive social responsibility and financial performance. Further, I address the issue of reverse causality and other sources of endogeneity by employing a dynamic panel model with a system generalized methods of moments regression. A sample of 6,528 observations across a total of 18 years of data is the foundation of my analysis. The results suggest that companies experience an immediate negative effect on financial performance from proactive social action, which becomes positive in the subsequent period. These findings hold considerable implications for both theory and practice.
Optical control of energy-level structure of few electrons in AlGaAs/GaAs quantum dots
Creators: name: Kalliakos, Sokratis
name: Pellegrini, Vittorio
name: Garcia, Cesar Pascual
name: Pinczuk, Aron
name: Pfeiffer, Loren N.
name: West, Ken. W.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Optical control of the lateral quantum confinement and number of electrons confined in nanofabricated GaAs/AlGaAs quantum dots is achieved by illumination with a weak laser beam that is absorbed in the AlGaAs barrier. Precise tuning of energy-level structure and electron population is demonstrated by monitoring the low-lying transitions of the electrons from the lowest quantum-dot energy shells by resonant inelastic light scattering. These findings open the way to the manipulation of single electrons in these quantum dots without the need of external metallic gates.
description: To appear in NanoLetters
On the number of zeros of diagonal cubic forms over finite fields
Creators: name: Hong, Shaofang
name: Zhu, Chaoxi
Publisher: name: arXiv
Year: 2020
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: Let ${\mathbb F}_q$ be the finite field with $q=p^k$ elements with $p$ being a prime and $k$ be a positive integer. For any $y, z\in\mathbb{F}_q$, let $N_s(z)$ and $T_s(y)$ denote the numbers of zeros of $x_1^{3}+\cdots+x_s^3=z$ and $x_1^3+\cdots+x_{s-1}^3+yx_s^3=0$, respectively. Gauss proved that if $q=p, p\equiv1\pmod3$ and $y$ is non-cubic, then $T_3(y)=p^2+\frac{1}{2}(p-1)(-c+9d)$, where $c$ and $d$ are uniquely determined by $4p=c^2+27d^2,~c\equiv 1 \pmod 3$ except for the sign of $d$. In 1978, Chowla, Cowles and Cowles determined the sign of $d$ for the case of $2$ being a non-cubic element of ${\mathbb F}_p$. But the sign problem is kept open for the remaining case of $2$ being cubic in ${\mathbb F}_p$. In this paper, we solve this sign problem by determining the sign of $d$ when $2$ is cubic in ${\mathbb F}_p$. Furthermore, we show that the generating functions $\sum_{s=1}^{\infty} N_{s}(z) x^{s}$ and $\sum_{s=1}^{\infty} T_{s}(y)x^{s}$ are rational functions for any $z, y\in\mathbb F_q^*:=\mathbb F_q\setminus \{0\}$ with $y$ being non-cubic over ${\mathbb F}_q$ and also give their explicit expressions. This extends the theorem of Myerson and that of Chowla, Cowles and Cowles.
description: 13 pages
Πελατοκεντρική προσέγγιση CRM (Customer Relationship management) στον τομέα των Υπηρεσιών:
Creators: name: Μπόλλα, Χρυσοπηγή Αστέριου
Publisher: name: Aristotle University of Thessaloniki
Year: 2008
Subjects: Διοίκηση πελατειακών σχέσεων
Διατήρηση πελάτη
Γνώση για πελάτη
Τεχνολογία
Επικερδείς πελάτες
Κέρδος
CRM
Customer retention
Knowledge
Technology
Key customers
Profit

description: Εκτενής παρουσίαση της νέας φιλοσοφίας CRM για τις επιχειρήσεις, εννοιών κλειδιά πχ. αξία πελάτη, ανταγωνιστικό πλεονέκτημα. Βάσει γνώσης και ανάλυση τομέα Υπηρεσιών. Παρουσίαση θεωρητικών μοντέλων CRM και έπειτα πρόταση ενός νέου μοντέλου μέσω εμπειρικής μελέτης σε επιχειρήσεις του ελλαδικού χώρου.
description: Presentation of the philosophie of the new strategie of enterprises, called CRM, Presentation of key words for CRM as CLV (customer lifetime value), knowledge management and services vs products. Lastly presentation of theoretical models of CRM and proposal of new one model by research to Greek enterprises.
The formation of spiral arms and rings in barred galaxies
Creators: name: Romero-Gomez, M.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We propose a theory to explain the formation of both spirals and rings in barred galaxies using a common dynamical framework. It is based on the orbital motion driven by the unstable equilibrium points of the rotating bar potential. Thus, spirals, rings and pseudo-rings are related to the invariant manifolds associated to the periodic orbits around these equilibrium points. We examine the parameter space of three barred galaxy models and discuss the formation of the different morphological structures according to the properties of the bar model. We also study the influence of the shape of the rotation curve in the outer parts, by making families of models with rising, flat or falling rotation curves in the outer parts. The differences between spiral and ringed structures arise from differences in the dynamical parameters of the host galaxies.
description: 6 pages, 3 figures, conference proceedings of "Semaine de l'Astrophysique Francaise", Grenoble 2007, eds. J. Bouvier, A. Chalabaev, C. Charbonnel
Schopenhauer and beckett : theatre of asceticism
Creators: name: Thomas, Martin Lee
Publisher: name: The Australian National University
Year: 2015

description: It is the central argument of this thesis that the plays Waiting for Godot, Endgame, and Happy Days are Schopenhauerian-informed, Beckettian theatre of asceticism. By proposing this understanding of Beckettian tragedy, this work presents a challenge to the life-affirming reading of Beckettian art presented by Adorno, Cavell, Deleuze, Critchley, and Badiou, for whom Beckett's work exemplifies art's capacity to provide genuine resistance to nihilism. In contrast to the life-affirming interpretation of Beckett's work, I believe the spectator to the performance of these three Beckettian tragedies witnesses something unique in the history of theatre: deliberately generated, self-inflicted physical and mental suffering undertaken with the intention of attaining a painless, will-less, state. Beckett is the first tragedian to stage ascetic practice where, in Schopenhauerian terms, the human intellect refuses the agreeable and, instead, looks for disagreeable in its attempts to break the will. To understand Beckett's contribution to asceticism, it is vital that we understand Beckett's work in relation to Schopenhauer, Beckett's most important ascetic predecessor. In the process of developing his own ascetic method - that of representational deprivation - Beckett utilizes and develops the central aspects of Schopenhauer's philosophical system. By so doing, Beckett incorporates both ascetic and non-ascetic elements of Schopenhauerian philosophy into his own ascetic thought. These non-ascetic elements include Schopenhauer's understanding of the dynamically sublime, the experience of boredom, and the conception of the self as that comprised of willing and knowing subjects. Only by understanding the foundation upon which Beckettian asceticism is built can one then also appreciate the significant development of asceticism that one finds in Beckettian tragedy. On the Beckettian stage, one witnesses the practice of a variety of ascetic methods which focus on inhibiting the body, methods such as self-mortification, fasting, poverty, and celibacy. With a long history of implementation, these ascetic methods may be referred to as 'traditional' asceticism. It is this version of asceticism that Schopenhauer discusses at length in the Fourth Book of The World as Will and Representation. In addition to the depiction of traditional asceticism, Beckett employs the artistic medium of tragedy to display the effectiveness of radical ascetic methods of his own devising. These 'Beckettian' ascetic methods, which operate in conjunction with traditional methods, focus on depriving the will - that perpetually striving aspect of the self (WWR 1: 164-5) - of the knowledge that it requires to strive. In its attempts to attain the will-quieted state of 'nothingness', Beckettian asceticism starves the mind as much as it starves the body.
Prognostic value of HER2DX in early-stage HER2-positive breast cancer: a comprehensive analysis of 757 patients in the Sweden Cancerome Analysis Network—Breast dataset (SCAN-B)
Creators: name: Harbeck, N.
name: Ciruelos, E.
name: Tolaney, S.M.
name: Villacampa, G.
name: Pascual, T.
name: Marín-Aguilera, M.
name: Martínez-Sáez, O.
name: Martin, M.
name: Paré, L.
name: Curigliano, G.
name: Brasó-Maristany, F.
name: Perou, C.M.
name: Vivancos, A.
name: Carey, L.A.
name: Cortés, J.
name: Conte, P.
name: Villagrasa, P.
name: Prat, A.
name: Fernandez, A.
name: Parker, J.S.
Publisher: name: Elsevier
Year: 2024

description: BACKGROUND: The HER2DX risk-score has undergone rigorous validation in prior investigations involving patients with early-stage human epidermal growth factor receptor 2 (HER2)-positive (HER2+) breast cancer. In this study, we present the outcomes of the HER2DX risk-score within the most recent release of the Sweden Cancerome Analysis Network-Breast (SCAN-B) HER2+ cohort. This updated examination benefits from a larger patient sample, an extended follow-up duration, and detailed treatment information.
MATERIALS AND METHODS: Clinical and RNAseq data from the SCAN-B dataset were retrieved from Gene Expression Omnibus (GSE81538). Among the 6600 patients, 819 had HER2+ breast cancer, with 757 individuals with research-based HER2DX risk-scores and corresponding survival outcomes. The HER2DX risk-score was evaluated (i) as a continuous variable and (ii) using predefined cut-offs. The primary endpoint for this study was overall survival (OS). The Kaplan-Meier method and Cox models were used to estimate OS and a multistate model with four states was fitted to better characterize patients' follow-up.
RESULTS: The median follow-up time was 7.5 years (n = 757). The most common systemic therapy was chemotherapy with trastuzumab (82.0%) and most tumors were classified as T1-T2 (97.1%). The HER2DX risk-score as a continuous variable was significantly associated with OS after adjustment for clinical variables and treatment regimen [hazard ratios (HR) per 10-unit increment = 1.31, 95% confidence interval (CI) 1.13-1.51, P < 0.001] as well as within predefined risk groups (high versus low; HR = 2.57, 95% CI 1.36-4.85, P < 0.001). Patients classified as HER2DX high-risk also had higher risk of (i) breast cancer recurrence and (ii) death without previous recurrence. Within the subgroup of HER2+ T1N0 tumors (n = 297), those classified as high-risk demonstrated inferior OS compared to low-risk tumors (7-year OS 77.8% versus 96.8%, P < 0.001). The HER2DX mRNA ERBB2 score was associated with clinical HER2 status (area under the receiver operating characteristic curve = 0.91).
CONCLUSIONS: In patients with early-stage HER2+ breast cancer, HER2DX risk-score provides prognostic information beyond clinicopathological variables, including treatment regimen with or without trastuzumab.
Additional file 1 of Systematic review: bioethical implications for COVID-19 research in low prevalence countries, a distinctly different set of problems
Creators: name: Skapetis, Tony
name: Law, Constance
name: Rodricks, Rohan
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: PRISMA checklist.
Nanoscale detection of metastable states in porous and granular media
Creators: name: Ilin, Eduard
name: Li, Yaofa
name: Colla, Eugene V.
name: Christensen, Kenneth T.
name: Sahimi, Muhammad
name: Marchevsky, Maxim
name: Frailey, Scott M.
name: Bezryadin, Alexey
Publisher: name: arXiv
Year: 2020
Subjects: subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Microseismicity in subsurface geologic environments, such as sandstone gas reservoirs, is expected in the presence of liquid or gas injection. Although difficult to predict, the potential for microseismic events is important to field-scale projects, such as geologic storage of CO2 whereby the gas is injected into natural sandstone formations. We conjecture that a primary factor causing microseismicity is the existence of metastable states in granular porous medium and provide experimental evidence for its validity. External perturbation trigger abrupt relaxation events, which, with a certain probability, can grow into macroscopic microseismic events. Here the triggering perturbation is produced by cooling to a cryogenic temperature. As the "sensor" for the abrupt relaxation events we use thin Al films deposited on the sandstone surface. We show that as the temperature is varied, the films' resistance exhibits sharp jumps, which we attribute to mechanical restructuring or microfractures in the fabric of the sandstone. We checked the superconducting characteristics of the Al thin films on the sandstone and found microwave-induced Shapiro steps on the voltage-current diagrams. Such quantized steps provide indicates that the film is made of a network of nanobridges, which makes it ever more sensitive to abrupt relaxation events occurring in the substrate, i.e., in the underlying sandstone.
Photometry of a Galactic field at l = 232, b = -6. The old open cluster Auner 1, the Norma-Cygnus spiral arm and the signature of the warped Galactic Thick Disk
Creators: name: Carraro, Giovanni
name: Moitinho, Andre'
name: Zoccali, Manuela
name: Vazquez, Ruben
name: Baume, Gustavo
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We perform a detailed photometric study of the stellar populations in a Galactic Field at l = 232, b = -6 in the Canis Major (CMa) constellation. We present the first U,B,V,I photometry of the old open cluster Auner1 and determine it to be 3.25 Gyr old and to lie at 8.9 kpc from the Sun. In the background of the cluster, at more than 9 kpc, we detect a young population most probably associated to the Norma Cygnus spiral arm. Furthermore, we detect the signature of an older population and identify its Turn Off and Red Giant Branch. This population is found to have a mean age of 7 Gyrs and a mean metallicity of Z = 0.006 . We reconstruct the geometry of the stellar distribution and argue that this older population - often associated to the Canis Major {\it galaxy}- belongs in fact to the warped old thin/thick disk component along this line of sight.
description: 19 pages, 7 eps figures (some degraded), accepted for publication in the Astronomical Journal
Χρήση της σχέσης ειδών επιφάνειας στην πρόβλεψη του ρυθμού απώλειας των ειδών
Creators: name: Κυριακίδου, Πολύμνια Αιμίλιου
Publisher: name: Aristotle University of Thessaloniki
Year: 2008
Subjects: Σχέση ειδών επιφάνειας (SAR)
Μείωση αφθονίας
Ρυθμός εξαφάνισης
Λογαριθμοκανονική κατανομή
Μεταπληθυσμιακή θεωρία
Species-area relationship
Abundance reduction
Extinction rates
Lognormal destribution
Metapopulation theory

description: Η σχέση ειδών επιφάνειας (SAR) έχει χρησιμοποιηθεί ευρέως σε μαθηματικά μοντέλα που χρησιμοποιούνται για την πρόβλεψη του ρυθμού απώλειας των ειδών. Πολλές θεωρίες όπως η ουδέτερη θεωρία του Hubbell και η μεταπληθυσμιακή θεωρία έχουν προσπαθήσει να μοντελοποιήσουν την δυναμική των πληθυσμών ώστε να είναι δυνατή η εκτίμηση μετά από απώλεια ενδιαιτήματος. Στα πλαίσια της εργασίας αυτής αναπτύχθηκε ένα μαθηματικό μοντέλο που ενσωματώνει στοιχεία από διάφορες θεωρίες και δίνει ικανοποιητικά και αληθοφανή αποτελέσματα σε υποθετικά δεδομένα.
description: Species area relationship has been widely used in mathematical models to predict rates of species loss. Many theories like Hubbell's neutral theory and metapopulation theory have tried to modelise the population dynamics so as to be able to predict the reduction after habitat loss. For this thesis, we developed a mathematical dynamic model that incorporates elements from various theories and gives satisfactory results when tested on hypothetical data.
Elementary counsellor education: perspectives from the field
Creators: name: Paterson, David
Publisher: name: University of British Columbia
Year: 2009

description: The purpose of this study was to examine the perceptions of British Columbia elementary school counsellors, in terms of the following primary research questions: (a) What counsellor competencies were included as part of each elementary counsellor's specialized educational or graduate program, (b) how effective was the educational content and experience in these competency areas, (c) how important is the educational content and experience in these competency areas with respect to their current role as elementary school counsellors, (d) what counsellor competencies are perceived as strengths and weaknesses of elementary counsellor education programs, and (e) what areas should be included in elementary graduate training programs to make them more effective? A list of B.C. elementary school counsellors was developed and 219 elementary school counsellors (67%) completed and returned the questionnaire. Respondents indicated that preparation related to the context of the elementary school was of primary importance to them. Theories were highly emphasized and well taught by counsellor education programs, but were viewed as less important than specific counselling skills and interventions. Implications of this study are discussed with respect to (a) contributing to existing literature in elementary counsellor role description, (b) assisting practicing elementary counsellors by outlining their challenges, recommendations and concerns, and (c) contributing to the development and relevance of elementary counsellor education programs.