cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
An Advanced Solvent for the Caustic-Side Solvent Extraction of Cesium from Nuclear Waste: Comparing Lipophilic Guanidines for Improved Hydrolytic Stability
Creators: name: Bessen, Nathan P.
name: Moyer, Bruce A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Plant Biology

description: An advanced solvent has been developed for application in the extraction of cesium from alkaline nuclear waste. Four lipophilic guanidines have been compared to arrive at a more hydrolysis-resistant suppressor component of the solvent. Plans call for deployment of the Next-Generation Caustic Side-Solvent Extraction (NG-CSSX) process at industrial scale for separation of radioactive Cs-137 from the legacy salt waste stored at the US Department of Energy Savannah River Site (SRS). In the solvent used in NG-CSSX, an alkyl guanidine “suppressor” component facilitates efficient stripping of the loaded cesium from the solvent. However, as typical of guanidine compounds, the suppressor previously used in the NG-CSSX solvent, N,N‘,N’’-tri(3,7-dimethyloctyl)guanidine (TiDG), suffers from hydrolytic degradation under process conditions. Recently, the sterically hindered alkyl guanidine N,N’-dicyclohexyl-N’’-(10-nonadecyl)guanidine (DCNDG) has been found to offer 8 to 44 times greater hydrolysis resistance than TiDG. Here, the process performance characteristics of the NG-CSSX solvent incorporating DCNDG are determined in comparison with TiDG and two other guanidine suppressors. The solvent has been adjusted in density to accommodate use in the SRS Salt Waste Processing Facility and tested under aggressive bench-scale conditions intended to increase plant throughput. Experiments include the effect of ageing at normal and off-normal temperatures of the distribution of Cs+ through the NG-CSSX process, the fate and effects of guanidine degradation products, suppressor capacity, coalescence times for aqueous-solvent dispersions, tendency for emulsification, third-phase formation, and degree of protonation of the guanidine in stripping. While the chosen structures of the four compared guanidines mainly effect differences in stability, subtle differences in other system properties such as emulsion formation and suppressor capacity provide insight into the function of this important solvent component. In comparison with TiDG and two other guanidines, DCNDG provides greatly increased stability while not compromising the excellent functional properties of the NG-CSSX solvent.
$\widehat{sl(2)}$ decomposition of denominator formulae of some BKM Lie superalgebras
Creators: name: Govindarajan, Suresh
name: Shabbir, Mohammad
name: Viswanath, Sankaran
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Number Theory (math.NT)
subject: Representation Theory (math.RT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We study a family of Siegel modular forms that are constructed using Jacobi forms that arise in Umbral moonshine. All but one of them arise as the Weyl-Kac-Borcherds denominator formula of some Borcherds-Kac-Moody (BKM) Lie superalgebras. These Lie superalgebras have a $\widehat{sl(2)}$ subalgebra which we use to study the Siegel modular forms. We show that the expansion of the Umbral Jacobi forms in terms of $\widehat{sl(2)}$ characters leads to vector-valued modular forms. We obtain closed formulae for these vector-valued modular forms. In the Lie algebraic context, the Fourier coefficients of these vector-valued modular forms are related to multiplicities of roots appearing on the sum side of the Weyl-Kac-Borcherds denominator formulae.
description: 37 pages
On the Convexity of a Fragment of Pure Set Theory with Applications within a Nelson-Oppen Framework
Creators: name: Cantone, Domenico
name: De Domenico, Andrea
name: Maugeri, Pietro
Publisher: name: arXiv
Year: 2021
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: The Satisfiability Modulo Theories (SMT) issue concerns the satisfiability of formulae from multiple background theories, usually expressed in the language of first-order predicate logic with equality. SMT solvers are often based on variants of the Nelson-Oppen combination method, a solver for the quantifier-free fragment of the combination of theories with disjoint signatures, via cooperation among their decision procedures. When each of the theories to be combined by the Nelson-Oppen method is convex (that is, any conjunction of its literals can imply a disjunction of equalities only when it implies at least one of the equalities) and decidable in polynomial time, the running time of the combination procedure is guaranteed to be polynomial in the size of the input formula. In this paper, we prove the convexity of a fragment of Zermelo-Fraenkel set theory, called Multi-Level Syllogistic, most of whose polynomially decidable fragments we have recently characterized.
description: In Proceedings GandALF 2021, arXiv:2109.07798
Differential item functioning of the tinnitus handicap inventory across gender groups and subjects with or without hearing loss
Creators: name: Gos, Elżbieta
name: Sagan, Adam
name: Raj-Koziak, Danuta
name: Skarzynski, Piotr H.
name: Skarzynski, Henryk
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Tinnitus is a phantom sound sensation without an external sound source. Due to its subjective and multifaceted nature it is measured using multi-item self-reported instruments. Many well-validated tinnitus-related questionnaires are available for clinical practice and scientific research, but so far no attention has been paid to their measurement invariance. The study aimed to examine measurement invariance of the Tinnitus Handicap Inventory with regard to gender and hearing impairment, and to identify the items that show differential item functioning (DIF) across the groups. This is a retrospective study using medical data from patients with tinnitus. They completed the Tinnitus Handicap Inventory (THI) and underwent pure-tone audiometry. 1106 adult patients with tinnitus (554 women and 552 men; 320 with normal hearing and 786 with hearing loss), aged 19–84 years. In the analysis, multi-group confirmatory factor analysis, hybrid ordinal logistic regression, Kernel smoothing in Item Response Theory, and lasso regression were applied. Measurement invariance was demonstrated across gender, but across hearing status the measurement was non-invariant. Five items were found to have DIF. Researchers and clinicians should be aware of the potential risk of response bias when tinnitus severity is evaluated.
On the size of disjunctive formulas in the $μ$-calculus
Creators: name: Kupke, Clemens
name: Marti, Johannes
name: Venema, Yde
Publisher: name: arXiv
Year: 2021
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: F.4.1; F.1.1; I.2.4

description: A key result in the theory of the modal mu-calculus is the disjunctive normal form theorem by Janin & Walukiewicz, stating that every mu-calculus formula is semantically equivalent to a so-called disjunctive formula. These disjunctive formulas have good computational properties and play a pivotal role in the theory of the modal mu-calculus. It is therefore an interesting question what the best normalisation procedure is for rewriting a formula into an equivalent disjunctive formula of minimal size. The best constructions that are known from the literature are automata-theoretic in nature and consist of a guarded transformation, i.e., the constructing of an equivalent guarded alternating automaton from a mu-calculus formula, followed by a Simulation Theorem stating that any such alternating automaton can be transformed into an equivalent non-deterministic one. Both of these transformations are exponential constructions, making the best normalisation procedure doubly exponential. Our key contribution presented here shows that the two parts of the normalisation procedure can be integrated, leading to a procedure that is single-exponential in the closure size of the formula.
description: In Proceedings GandALF 2021, arXiv:2109.07798
Developing a prototype web-based decision aid for adults with hearing loss
Creators: name: Hickson, Louise
name: Nickbakht, Mansoureh
name: Timmer, Barbra H. B.
name: Dawes, Piers
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Science Policy
Hematology

description: To develop a prototype of a decision aid to be used on a website for adults with hearing loss. Design: Development was guided by the International Patient Decision Aid Standards (IPDAS) and included a survey and think-aloud process. A total of 153 participants completed a survey about what to include in the decision aid (111 adults with hearing loss, 21 family members of adults with hearing loss, and 21 professionals). Six adults with hearing loss and six family members participated in a think-aloud process to provide feedback as they used an initial version of the decision aid. In the survey, 26 of the 38 potential items were identified as being highest priority and were included in the initial version of the decision aid. This initial version was then tested in the think-aloud sessions and a prototype of a web-based version was developed based on participant responses related to: 1) information on the decision aid, 2) ease of use, 3) layout and orders of the items, 4) satisfaction, 5) areas for improvement (e.g., need for graphics). The methodologies used in this study are recommended for developing decision aids for adults with acquired hearing loss.
From B[e] to A[e]. On the peculiar variations of the SMC supergiant LHA 115-S 23 (AzV 172)
Creators: name: Kraus, Michaela
name: Fernandes, Marcelo Borges
name: Kubat, Jiri
name: de Araujo, Francisco X.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Optical observations from 1989 of the SMC B[e] supergiant star S23 revealed the presence of photospheric HeI absorption lines. In our high-resolution optical spectra from 2000, however, we could not identify any HeI line. The observed changes in spectral behaviour of S23 lead to different spectral classifications at different observing epochs. The aim of this research is, therefore, to find and discuss possible scenarios that might cause a disappearance of the photospheric HeI absorption lines within a period of only 11 years. From our high-resolution optical spectra, we perform a detailed investigation of the different spectral appearances of S23. We further determine the projected rotational velocities of S23 in the two epochs of observations. Based on its spectral appearance in 2000, we classify S23 as A1Ib star with an effective temperature of about 9000 K. Further, an interstellar extinction value of E(B-V) = 0.03 is derived. This is considerably lower than the previously published value, which means that, if the circumstellar extinction due to the stellar wind is neglected, the interstellar extinction, and hence the luminosity of the star, are overestimated. We derive a rotation velocity of v sin i = 150km/s, which means that S23 is rotating with about 75% of its critical speed. The object S23 is thus the fourth B[e] supergiant with confirmed high projected rotational velocity. The most striking result is the apparent cooling of S23 by more than 1500 K with a simultaneous increase of its rotation speed by about 35% within only 11 years. Since such a behaviour is excluded by stellar evolution theories, we discuss possible scenarios for the observed peculiar variations in S23.
description: 11 pages, 8 figures, accepted for publication in A&A
Proceedings Seventh Workshop on Proof eXchange for Theorem Proving
Creators: name: Keller, Chantal
name: Fleury, Mathias
Publisher: name: arXiv
Year: 2021
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: This volume of EPTCS contains the proceedings of the Seventh Workshop on Proof Exchange for Theorem Proving (PxTP 2021), held on 11 July 2021 as part of the CADE-28 online conference in Pittsburgh, USA. The PxTP workshop series brings together researchers working on various aspects of communication, integration, and cooperation between reasoning systems and formalisms, with a special focus on proofs. The progress in computer-aided reasoning, both automated and interactive, during the past decades, made it possible to build deduction tools that are increasingly more applicable to a wider range of problems and are able to tackle larger problems progressively faster. In recent years, cooperation between such tools in larger systems has demonstrated the potential to reduce the amount of manual intervention. Cooperation between reasoning systems relies on availability of theoretical formalisms and practical tools to exchange problems, proofs, and models. The PxTP workshop series strives to encourage such cooperation by inviting contributions on all aspects of cooperation between reasoning tools, whether automatic or interactive.
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 5 (198)]
Creators: name: Giangaleazzo
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1386
Subjects: subject: Sonstige weltliche Aussteller
subject: Urkunde
subject: 090

description: [Gian Galeazzo Visconti,] Herr von Mailand, comes virtutum und imperialis vicarius generalis, bestätigt dem Rhetor Berardus Tronchetus, praeceptor der domus St. Antonii von Cremona und Daniate, die weitere Abgabenfreiheit seiner Institution.
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 5 (216)]
Creators: name: Andreas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1391
Subjects: subject: Sonstige geistliche Aussteller
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Andreas de Verderio, Abt des Klosters St. Thomae in Cremona, und weitere genannte Geistliche dieses Klosters verpachten dem Benedinus de Torexinis, Sohn des verstorbenen Bertolinus, aus der Nachbarschaft von St. Prosperi in Cremona ein Stück bebautes Land, gelegen ebendort.
Mexico: The Main Threats Identified for Tangible and Intangible Assets as of 2017 / Risks and Socio-cultural Impacts in the Sierra Tarahumara, State of Chihuahua
Creators: name: Audefroy, Joel F.
name: Serrano, Francisco Hernández
Publisher: name: Heritage at Risk
Year: 2021

description: Heritage at Risk, H@R 2016-2019
India: Case Study
Creators: name: Kiran Joshi, Ritika Jharia,
name: Desai, Jigna
name: Makhija, Smita Datta
Publisher: name: Heritage at Risk
Year: 2021

description: Case Study 1: Victorian Gothic and Art Deco Ensembles of Mumbai and its Esplanade Mansion / Case Study 2: The Risk of ‘Contemporising’ Historic Urban Landscapes – The Case of the Sacred Town of Varanasi / Case Study 3: Saving Chandni Chowk, the Mughal Ceremonial Avenue of Shahjahanabad
description: Heritage at Risk, H@R 2016-2019
Statistical versus neural network-embedded swarm intelligence optimization of a metallo-neutral-protease production: activity kinetics and food industry applications
Creators: name: Ekpenyong, Maurice George
name: Antai, Sylvester Peter
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: An integrated approach involving response surface methodology (RSM) and artificial neural network-ant-colony hybrid optimization (ANN-ACO) was adopted to develop a bioprocess medium to increase the yield of Bacillus cereus neutral protease under submerged fermentation conditions. The ANN-ACO model was comparatively superior (predicted r2 = 98.5%, mean squared error [MSE] = 0.0353) to RSM model (predicted r2 = 86.4%, MSE = 23.85) in predictive capability arising from its low performance error. The hybrid model recommended a medium containing (gL−1) molasses 45.00, urea 9.81, casein 25.45, Ca2+ 1.23, Zn2+ 0.021, Mn2+ 0.020, and 4.45% (vv−1) inoculum, for a 6.75-fold increase in protease activity from a baseline of 76.63 UmL−1. Yield was further increased in a 5-L bioreactor to a final volumetric productivity of 3.472 mg(Lh)−1. The 10.0-fold purified 46.6-kDa-enzyme had maximum activity at pH 6.5, 45–55 °C, with Km of 6.92 mM, Vmax of 769.23 µmolmL−1 min−1, kcat of 28.49 s−1, and kcat/Km of 4.117 × 103 M−1 s−1, at 45 °C, pH 6.5. The enzyme was stabilized by Ca2+, activated by Zn2+ but inhibited by EDTA suggesting that it was a metallo-protease. The biomolecule significantly clarified orange and pineapple juices indicating its food industry application.
Finite Model Property and Bisimulation for LFD
Creators: name: Koudijs, Raoul
Publisher: name: arXiv
Year: 2021
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences
subject: F.4.1

description: Recently, Baltag and van Benthem introduced a decidable logic of functional dependence (LFD) that extends the logic of Cylindrical Relativized Set Algebras (CRS) with atomic local dependence statements. Its semantics can be given in terms of generalised assignment models or their modal counterparts, hence the logic is both a first-order and a modal logic. We show that LFD has the finite model property (FMP) using Herwig's theorem on extending partial isomorphisms, and prove a bisimulation invariance theorem characterizing LFD as a fragment of first-order logic.
description: In Proceedings GandALF 2021, arXiv:2109.07798. An extended version of this paper appears at arXiv:2107.06042
Spatial structure and population dynamics in an insect epidemic ecosystem
Creators: name: Clark, William C.
Publisher: name: University of British Columbia
Year: 2010

description: A major theme in contemporary ecology is how, and whether, spatial structure considerations such as dispersal and environmental heterogeneity must be invoked for satisfactory explanations of observed population dynamics. This study shows how behavioral and environmental components of spatial structure shape emergent population dynamics in one relatively simple and well studied natural ecosystem: the spruce budworm (Choristoneura fumiferana, Lepidoptera: Tortricidae), and the boreal forests of eastern Canada which it periodically defoliates. The study begins by partitioning spatial structure considerations into components of local structure, dispersal processes, and local uniqueness. Existing data on the budworm-forest ecosystem are then synthesized into an array of mathematical models reflecting possible relationships among those components. Numerical simulation techniques are used to explore these models. Subsequent qualitative analyses simplify the simulations, focussing on equilibrium isoclines for population growth and the associated phase portraits of system dynamics. The principle methodological contribution of the study is its explicit inclusion of dispersal effects in these qualitative analyses. Model predictions are compared with a variety of real world experiments and observations to assess the limits of present understanding. The study concludes that spatial population dynamics in the budworm ecosystem can be explained largely in terms of local structure relationships, modified to account for the local effects of insect immigration and emigration. Detailed knowledge of dispersal distance or direction distributions is unnecessary. Population dynamics are shown to be sensitive to (a) the proportion of moths dispersing, and its modification by habitat conditions or moth density; (b.) the survival of passively dispersing young larvae, and its dependence on forest structure; (c) the relationship between foliage quality/quantity and budworm feeding; and (d) predation by vertebrates on larvae at low insect densities. Priorities for future research are identified, and some retrospective doubts concerning the utility of the population dynamics perspective in ecology are expressed.
Germany: The Temple Synagogue in Hamburg’s Neustadt, i.a.
Creators: name: Schilling, Jörg
name: Bredenbeck, Martin
name: Buttlar, Adrian Von
name: Bartetzko, Daniel
name: Felix Torkar, Gunnar Klack,
name: Lucia Schaub, Anna Galda
name: Peter Schneider, Constanze Röhl,
Publisher: name: Heritage at Risk
Year: 2021

description: The Temple Synagogue in Hamburg’s Neustadt / Bad Neuenahr: Great Frustration in the Bauhaus Year / Illegal Destruction of Berlin’s St. Hedwig’s Cathedral Started in October 2019 / The Roundhouse in Berlin-Pankow / Berlin: Brutalist Icons Threatened by Demolition / Focus Eastern Modernism: The Chemnitz Pylon Roof / F1 (Fertigungshalle 1) and the Material Remains of the Former Heeresversuchsanstalt Peenemünde
description: Heritage at Risk, H@R 2016-2019
Georgia: Batumi Urban Heritage at Risk / David Gareji Monasteries and Hermitage / Khada Cultural Landscape at Risk
Creators: name: Inaishvili, Nino
name: Gudjabidze, Shota
name: Dvalishvili, Mariam
name: Suramelashvili, Manana
Publisher: name: Heritage at Risk
Year: 2021

description: Heritage at Risk, H@R 2016-2019
Resonant and first-order dipolar interactions between ultracold molecules in static and microwave electric fields
Creators: name: Karman, Tijs
name: Yan, Zoe Z.
name: Zwierlein, Martin
Publisher: name: arXiv
Year: 2021
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We theoretically study collisions between ultracold polar molecules that are polarized by microwave or static electric fields. We systematically study the dependence on field strength, microwave polarization, and detuning from rotational transitions. We calculate the loss in two-body collisions that is observable experimentally and compare to the results expected for purely first-order dipolar interactions. For ground state molecules polarized by a static electric field, the dynamics are accurately described by first-order dipolar interactions. For microwave dressing, instead, resonant dipolar collisions dominate the collision process, in which molecules reorient along the intermolecular axis and interact with the full strength of the transition dipole. For red detuning, reorientation can only be suppressed at extreme Rabi frequencies. For blue detuned microwaves, resonant dipolar interactions dominate even for high Rabi frequencies, leading to microwave shielding for circular polarization and structured losses due to resonances for linear polarization. The results are presented numerically for fermionic $^{23}$Na$^{40}$K and bosonic $^{23}$Na$^{39}$K molecules.
Polarization proximity effect in isolator crystal pairs
Creators: name: Linzon, Yoav
name: Ferrera, Marcello
name: Razzari, Luca
name: Pignolet, Alain
name: Morandotti, Roberto
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We experimentally studied the polarization dynamics (orientation and ellipticity) of near infrared light transmitted through magnetooptic Yttrium Iron Garnet crystal pairs using a modified balanced detection scheme. When the pair separation is in the sub-millimeter range, we observed a proximity effect in which the saturation field is reduced by up to 20%. 1D magnetostatic calculations suggest that the proximity effect originates from magnetostatic interactions between the dipole moments of the isolator crystals. This substantial reduction of the saturation field is potentially useful for the realization of low-power integrated magneto-optical devices.
description: submitted to Optics Letters
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 5 (181)]
Creators: name: Egidiolus De Maltrauerssiis
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1381
Subjects: subject: Sonstige geistliche Aussteller
subject: Quittung
subject: Urkunde
subject: 090

description: Egidiolus de Maltrauerssiis, subcollector der camera Apostolica, bestätigt, von Martinus, genannt Pasius, Prior des Klosters St. Thomae in Cremona, stellvertretend für Rafaynus de Pizanuliis, Abt dieses Klosters, eine Abgabe an die Römische Kirche erhalten zu haben.
Reconfigurable Broadcast Networks and Asynchronous Shared-Memory Systems are Equivalent
Creators: name: Balasubramanian, A. R.
name: Weil-Kennedy, Chana
Publisher: name: arXiv
Year: 2021
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences

description: We show the equivalence of two distributed computing models, namely reconfigurable broadcast networks (RBN) and asynchronous shared-memory systems (ASMS), that were introduced independently. Both RBN and ASMS are systems in which a collection of anonymous, finite-state processes run the same protocol. In RBN, the processes communicate by selective broadcast: a process can broadcast a message which is received by all of its neighbors, and the set of neighbors of a process can change arbitrarily over time. In ASMS, the processes communicate by shared memory: a process can either write to or read from a shared register. Our main result is that RBN and ASMS can simulate each other, i.e. they are equivalent with respect to parameterized reachability, where we are given two (possibly infinite) sets of configurations C and C' defined by upper and lower bounds on the number of processes in each state and we would like to decide if some configuration in C can reach some configuration in C'. Using this simulation equivalence, we transfer results of RBN to ASMS and vice versa. Finally, we show that RBN and ASMS can simulate a third distributed model called immediate observation (IO) nets. Moreover, for a slightly stronger notion of simulation (which is satisfied by all the simulations given in this paper), we show that IO nets cannot simulate RBN.
description: In Proceedings GandALF 2021, arXiv:2109.07798. A long version of this paper, containing all proofs, appears at arXiv:2108.07510
Recombinant expression and tryptophan-assisted analysis of human sweet taste receptor T1R3’s extracellular domain in sweetener interaction studies
Creators: name: Jin, Soo-Bin
name: Kim, Hyun-A
name: Shin, Ji-Ae
name: Jung, Na-Hee
name: Park, Seo-Young
name: Hong, Sungguan
name: Kong, Kwang-Hoon
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Virology

description: The human palate can discern multiple tastes; however, it predominantly perceives five fundamental flavors: sweetness, saltiness, sourness, bitterness, and umami. Sweetness is primarily mediated through the sweet taste receptor, a membrane-bound heterodimeric structure comprising T1R2-T1R3. However, unraveling the structural and mechanistic intricacies of the sweet taste receptor has proven challenging. This study aimed to address this knowledge gap by expressing an extracellular N-terminal domain encompassing the cysteine-rich domain of human hT1R3 (hT1R3-TMD) in Escherichia coli. The expressed protein was obtained as inclusion bodies, purified by metal affinity chromatography, and refolded using the dilution-refolding method. Through rigorous analysis, we confirmed the successful refolding of hT1R3-TMD and elucidated its structural characteristics using circular dichroism spectroscopy. Notably, the refolded protein was found to exist as either a monomer or a dimer, depending on its concentration. A tryptophan fluorescence quenching assay revealed that the dissociation constants for sucrose, sucralose, and brazzein were >9500 μM, 2380 μM and 14.3 μM, respectively. Our findings highlight the utility of this E. coli expression system for producing functional hT1R3-TMD for investigations and demonstrate the efficacy of the tryptophan fluorescence quenching assay in revealing complex interactions between sweet taste receptors and various sweeteners.
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 5 (183)]
Creators: name: Petrolus Grassus
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1382
Subjects: subject: Sonstige weltliche Aussteller
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Petrolus Grassus, Sohn des verstorbenen Girardus, wohnhaft in Monza, bestätigt, von Johaninus de Marliano, Sohn des verstorbenen Rugerius, wohnhaft an der porta Orientalis in der parochia St. Michaelis subtus domum in Mailand, im Namen und zum Vorteil der Ymilia de Marliano, Tochter des Johaninus, eine Geldzahlung erhalten zu haben.
Microwave-enhanced hydrolysis of cellulose by acidic ionic liquids
Creators: name: Liu, Meng-meng
name: Zhang, Liang-yan
name: Liu, Zhen
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: In the [Bmim]Cl reaction medium, five different acidic ionic liquids were used as catalysts to study the effects of reaction time, reaction temperature, system water content, catalyst dosage, microwave power, and other factors on cellulose hydrolysis under microwave irradiation. The results showed that in the [Bmim]Cl reaction system, using N-methylpyrrolidone methylsulfonic acid salt as a catalyst, controlling the microwave reaction time at 10 min, reaction temperature at 130 °C, catalyst dosage at 1 g/g (cellulose), water addition at 0.756 μL/g ([Bmim]Cl), and microwave power at 480 W, resulted in the best cellulose hydrolysis effect with a glucose yield of 74.49%. Compared to conventional heating, the glucose yield increased by 24% and the hydrolysis time was reduced by 77%. Microwave irradiation significantly enhances the cellulose hydrolysis process in an ionic liquid medium.
Subcritical dynamo and hysteresis in a Babcock-Leighton type kinematic dynamo model
Creators: name: Vashishth, Vindya
name: Karak, Bidya Binay
name: Kitchatinov, Leonid
Publisher: name: arXiv
Year: 2021
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: In Sun and sun-like stars, it is believed that the cycles of the large-scale magnetic field are produced due to the existence of differential rotation and helicity in the plasma flows in their convection zones (CZs). Hence, it is expected that for each star, there is a critical dynamo number for the operation of a large-scale dynamo. As a star slows down, it is expected that the large-scale dynamo ceases to operate above a critical rotation period. In our study, we explore the possibility of the operation of the dynamo in the subcritical region using the Babcock--Leighton type kinematic dynamo model. In some parameter regimes, we find that the dynamo shows hysteresis behavior, i.e., two dynamo solutions are possible depending on the initial parameters -- decaying solution if started with weak field and strong oscillatory solution (subcritical dynamo) when started with a strong field. However, under large fluctuations in the dynamo parameter, the subcritical dynamo mode is unstable in some parameter regimes. Therefore, our study supports the possible existence of subcritical dynamo in some stars which was previously shown in a mean-field dynamo model with distributed $α$ and MHD turbulent dynamo simulations.
description: 11 pages, including 7 figures
Switching of antiferromagnetic states in LiCoPO$_4$ as investigated via the magnetoelectric effect
Creators: name: Kocsis, Vilmos
name: Tokunaga, Yusuke
name: Tokura, Yoshinori
name: Taguchi, Yasujiro
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The linear magnetoelectric (ME) effect allows for the selection or switching between two antiferromagnetic (AFM) states via the application of large electric ($E$) and magnetic ($H$) fields. Once an AFM state is selected, it is preserved by an energy barrier, even when the fields are removed. Using a simple phenomenological model, we find that this energy barrier, needed to switch the AFM state, is proportional to the product of the $E$ and $H$ coercive fields $(EH)_{\rm C}$. We measured the field and temperature dependence of $(EH)_{\rm C}$ in LiCoPO$_4$ for two different field configurations, and the data show the temperature variation of $(EH)_{\rm C}\sim(T_{\rm N}-T)^{3/2}$ in good agreement with the model. We also investigated the dynamics of the AFM domain switching using pulsed $E$-field measurements. It was found that the coercive field $(EH)_{\rm C}$ follows a power-law frequency dependence and is well described in the framework of Ishibashi-Orihara model, implying 1-dimensional character of domain wall propagation.
description: main + supplementary, 9+5 pages, 7+4 figures
researchdata@unige – 4 ans de pratiques
Creators: name: Claivaz, Jean-Blaise
Publisher: name: Zenodo
Year: 2021
Subjects: données de la recherche
DMP
PGD
plan de gestion des données
data management plan

description: L’équipe Research Data de l’Université de Genève était déjà constituée lorsque le dépôt d’un PGD (ou DMP) a été rendu obligatoire par le Fonds national suisse de la recherche scientifique (FNS) à l’automne 2018. Cela a permis à la bibliothèque de se profiler sur le sujet en proposant des services taillés sur mesure, détaillés dans cette présentation. Ces slides ont été présentés lors d'une visioconférence du mardi 26 janvier 2021 consacrée à la sensibilisation au plan de gestion des données et organisée par le GTSO Données de Couperin : https://visiodata3.sciencesconf.org/
Dati clinici, diritti di esclusiva e accesso ai farmaci
Creators: name: Corkovic, Ivan
Publisher: name: Zenodo
Year: 2024
Subjects: Intellectual Property
Trade Secret
Drugs
Data Exclusivity
Comparative Law

description: This research presents an analysis of data exclusivity and its impact on access to medicines, one of the essential elements for the full realization of the fundamental right to health. Data exclusivity is an exclusive right, defined by some as an intellectual property right, which grants the holder of a marketing authorization for a new medicine a period of exclusivity over the results of preclinical and clinical trials conducted for the purpose of obtaining that authorization. This mechanism prevents competing manufacturers from achieving approval of generic versions of the drug in question through the abbreviated or simplified procedure, which requires only the demonstration of bioequivalence through appropriate bioavailability studies instead of the submission of a full dossier of studies proving the safety and efficacy of the product.

 

For several decades, legislators have identified data exclusivity as a mechanism that can reconcile the diverse needs of the pharmaceutical industry, as it is believed to ensure the original drug developer the ability to recoup the substantial resources invested in the research and development of the product.  The events that have marked the past few years – particularly the Covid-19 pandemic – have raised renewed interest among the public and legislators in issues such as pharmaceutical innovation, clinical trials and the approval of new drug products. At the same time, with the management of this health crisis, some problematic profiles of the current system have emerged, especially with reference to the delicate balance between the interests of the pharmaceutical industry and the protection of the right to health. From this point of view, data exclusivity represents a highly controversial exclusive right, especially in the context of economically less developed countries, which frequently face health emergencies but lack the resources to ensure access to the expensive treatments produced by large American and European pharmaceutical companies.
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 5 (213)]
Creators: name: Girardus
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1389
Subjects: subject: Sonstige geistliche Aussteller
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Girardus de Bulliaci, cellerarius des Klosters St. Antonii Vienensis und praeceptor renversi, bestätigt, von Berardus Troncheti, praeceptor der domus St. Antonii Daniate im Bistum Cremona, eine Abgabenzahlung für das vergangene Jahr erhalten zu haben.
Adapting to the Behavior of Environments with Bounded Memory
Creators: name: Raju, Dhananjay
name: Ehlers, Rüdiger
name: Topcu, Ufuk
Publisher: name: arXiv
Year: 2021
Subjects: subject: Formal Languages and Automata Theory (cs.FL)
subject: Computer Science and Game Theory (cs.GT)
subject: FOS: Computer and information sciences
subject: D.2.3; B.1.2;

description: We study the problem of synthesizing implementations from temporal logic specifications that need to work correctly in all environments that can be represented as transducers with a limited number of states. This problem was originally defined and studied by Kupferman, Lustig, Vardi, and Yannakakis. They provide NP and 2-EXPTIME lower and upper bounds (respectively) for the complexity of this problem, in the size of the transducer. We tighten the gap by providing a PSPACE lower bound, thereby showing that algorithms for solving this problem are unlikely to scale to large environment sizes. This result is somewhat unfortunate as solving this problem enables tackling some high-level control problems in which an agent has to infer the environment behavior from observations. To address this observation, we study a modified synthesis problem in which the synthesized controller must gather information about the environment's behavior safely. We show that the problem of determining whether the behavior of such an environment can be safely learned is only co-NP-complete. Furthermore, in such scenarios, the behavior of the environment can be learned using a Turing machine that requires at most polynomial space in the size of the environment's transducer.
description: In Proceedings GandALF 2021, arXiv:2109.07798
Multi-color Near Infra-red Intra-day and Short Term Variability of the Blazar S5 0716+714
Creators: name: Gupta, Alok C.
name: Cha, Sang-Mok
name: Lee, Sungho
name: Jin, Ho
name: Pak, Soojong
name: Cho, Seoung-hyun
name: Moon, Bongkon
name: Park, Youngsik
name: Yuk, In-Soo
name: Nam, Uk-won
name: Kyeong, Jaemann
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this paper, we report results of our near-infrared (NIR) photometric variability studies of the BL Lacertae object S5 0716+714. NIR photometric observations spread over 7 nights during our observing run April 2-9, 2007 at 1.8 meter telescope equipped with KASINICS (Korea Astronomy and Space Science Institute Near Infrared Camera System) and J, H, and Ks filters at Bohyunsan Optical Astronomy Observatory (BOAO), South Korea. We searched for intra-day variability, short term variability and color variability in the BL Lac object. We have not detected any genuine intra-day variability in any of J, H, and Ks passbands in our observing run. Significant short term variability ~ 32.6%, 20.5% and 18.2% have been detected in J, H, Ks passbands, respectively, and ~ 11.9% in (J-H) color.
description: 24 pages, 3 figures, 4 tables, Accepted for Publication to Astronomical Journal
Mise en place, fonctionnement et évolution du service support aux PGD à INRAE
Creators: name: Cocaud, Sylvie
Publisher: name: Zenodo
Year: 2021
Subjects: données de la recherche
DMP
PGD
plan de gestion des données
data management plan

description: Nous présenterons le service support aux PGD mis en place à INRAE en 2017 et ferons un rapide bilan de l'utilisation des PGD dans l'institut. Nous montrerons comment l'accompagnement aux PGD peut permettre de proposer ou participer à d'autres services liés à la gestion des données de la recherche. Cette présentation a été réalisée lors d'une visioconférence du mardi 26 janvier 2021 consacrée à la sensibilisation au plan de gestion des données et organisée par le GTSO Données de Couperin : https://visiodata3.sciencesconf.org/
Development plan of a personalised comparison expert system of urinary infection treatments in general practice — the first development stage of CESDiT, the C̲ase-based precision medicine E̲xpert S̲ystem(ES) for D̲i̲agnostics and T̲herapy
Creators: name: Borgulya, Gábor
name: Schwager, Andreas
name: Kurotschka, Peter Konstantin
Publisher: name: Zenodo
Year: 2024

description: This poster was displayed, presented and discussed at the DEGAM 2024 congress.

The link to the abstract on the congress website is https://eventclass.it/degam2024/scientific/online-program/session?s=P-3, this website is archived at archive.org (click within the page for details) and archive.ph.
Rédaction de PGD et leur partage au Cirad
Creators: name: Deboin, Marie-Claude
Publisher: name: Zenodo
Year: 2021
Subjects: données de la recherche
DMP
PGD
plan de gestion des données
data management plan

description: Le projet "Appui à la rédaction des PGD et à la publication de données de recherche" figure dans la feuille de route 2019-2023 de la Délégation à l'information scientifique et technique (Dist) du Cirad. Outre l'accompagnement de porteurs de projets de recherche contractuels dans la rédaction de PGD, des modèles de PGD ont été produits pour un usage interne au Cirad ou pour être accessibles à tous via la plate-forme DMP OPIDoR. Une fiche-conseil "Rédiger un Plan de Gestion des Données en pratique" a été publiée sur le site internet CoopIST du Cirad. Des formations collectives au PGD ont été dispensées dans le cadre du plan de formation « Parcours numérique scientifique » du Cirad. Agritrop, l'archive ouverte des publications du Cirad a intégré le PGD comme type de document pouvant être déposé, avec en sortie la liste des PGD du Cirad non confidentiels. Enfin, un sondage a été mené fin 2020 auprès des collectifs de recherche et des personnels d'appui du Cirad pur mieux connaitre leurs pratiques de rédaction, partage et diffusion de PGD. Cette présentation a été réalisée lors d'une visioconférence du mardi 26 janvier 2021 consacrée à la sensibilisation au plan de gestion des données et organisée par le GTSO Données de Couperin : https://visiodata3.sciencesconf.org/
Hydrodynamic limit of gradient exclusion processes with conductances
Creators: name: Franco, Tertuliano
name: Landim, Claudio
Publisher: name: arXiv
Year: 2008
Subjects: subject: Probability (math.PR)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 60K35, 26A24, 35K55, 82C44

description: Fix a strictly increasing right continuous with left limits function $W: \bb R \to \bb R$ and a smooth function $Φ: [l,r] \to \bb R$, defined on some interval $[l,r]$ of $\bb R$, such that $0
SSPNet: Scale Selection Pyramid Network for Tiny Person Detection from UAV Images
Creators: name: Hong, Mingbo
name: Li, Shuiwang
name: Yang, Yuchao
name: Zhu, Feiyu
name: Zhao, Qijun
name: Lu, Li
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: With the increasing demand for search and rescue, it is highly demanded to detect objects of interest in large-scale images captured by Unmanned Aerial Vehicles (UAVs), which is quite challenging due to extremely small scales of objects. Most existing methods employed Feature Pyramid Network (FPN) to enrich shallow layers' features by combing deep layers' contextual features. However, under the limitation of the inconsistency in gradient computation across different layers, the shallow layers in FPN are not fully exploited to detect tiny objects. In this paper, we propose a Scale Selection Pyramid network (SSPNet) for tiny person detection, which consists of three components: Context Attention Module (CAM), Scale Enhancement Module (SEM), and Scale Selection Module (SSM). CAM takes account of context information to produce hierarchical attention heatmaps. SEM highlights features of specific scales at different layers, leading the detector to focus on objects of specific scales instead of vast backgrounds. SSM exploits adjacent layers' relationships to fulfill suitable feature sharing between deep layers and shallow layers, thereby avoiding the inconsistency in gradient computation across different layers. Besides, we propose a Weighted Negative Sampling (WNS) strategy to guide the detector to select more representative samples. Experiments on the TinyPerson benchmark show that our method outperforms other state-of-the-art (SOTA) detectors.
Maximally Localized Wannier Functions within the FLAPW formalism
Creators: name: Freimuth, F.
name: Mokrousov, Y.
name: Wortmann, D.
name: Heinze, S.
name: Blügel, S.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report on the implementation of the Wannier Functions (WFs) formalism within the full-potential linearized augmented plane wave method (FLAPW), suitable for bulk, film and one-dimensional geometries. The details of the implementation, as well as results for the metallic SrVO3, ferroelectric BaTiO3 grown on SrTiO3, covalently bonded graphene and a one-dimensional Pt-chain are given. We discuss the effect of spin-orbit coupling on the Wannier Functions for the cases of SrVO3 and platinum. The dependency of the WFs on the choice of the localized trial orbitals as well as the difference between the maximally localized and "first-guess" WFs are discussed. Our results on SrVO3 and BaTiO3, e.g. the ferroelectric polarization of BaTiO3, are compared to results published elsewhere and found to be in excellent agreement.
description: 13 pages, 9 figures, accepted for publication in Phys. Rev. B
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 5 (176)]
Creators: name: De Barbobus, Bernardus
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1379
Subjects: subject: Sonstige weltliche Aussteller
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Bernardus de Barbobus, Sohn des verstorbenen Marchinus, gelobt feierlich, dem Jacobus Marnis aus Soncino ein von diesem gewährtes Darlehen zurückzuzahlen.
title: Front Matter, Table of Contents, Preface, Conference Organization
Creators: name: Eppstein, David
Publisher: name: Schloss Dagstuhl – Leibniz-Zentrum für Informatik
Year: 2018
Subjects: subject: Front Matter
subject: Table of Contents
subject: Preface
subject: Conference Organization

description: Front Matter, Table of Contents, Preface, Conference Organization
description: LIPIcs, Vol. 101, 16th Scandinavian Symposium and Workshops on Algorithm Theory (SWAT 2018), pages 0:i-0:ix