cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Extension of a de novo TIM barrel with a rationally designed secondary structure element
Creators: name: Wiese, Jonas Gregor
name: Shanmugaratnam, Sooruban
name: Höcker, Birte
Publisher: name: University of Bayreuth
Year: 2021
Subjects: subject: (βα)8-barrel
subject: TIM barrel
subject: ab initio folding
subject: computational protein design
subject: enzyme design
subject: sTIM11
subject: 500
subject: 570

description: The ability to construct novel enzymes is a major aim in de novo protein design. A popular enzyme fold for design attempts is the TIM barrel. This fold is a common topology for enzymes and can harbor many diverse reactions. The recent de novo design of a four-fold symmetric TIM barrel provides a well understood minimal scaffold for potential enzyme designs. Here we explore opportunities to extend and diversify this scaffold by adding a short de novo helix on top of the barrel. Due to the size of the protein, we developed a design pipeline based on computational ab initio folding that solves a less complex sub-problem focused around the helix and its vicinity and adapt it to the entire protein. We provide biochemical characterization and a high-resolution X-ray structure for one variant and compare it to our design model. The successful extension of this robust TIM-barrel scaffold opens opportunities to diversify it towards more pocket like arrangements and as such can be considered a building block for future design of binding or catalytic sites.
Adolescents’ Experiences of Using a Smartphone Application Hosting a Closed-loop Algorithm to Manage Type 1 Diabetes in Everyday Life: Qualitative Study
Creators: name: Rankin, David
name: Kimbell, Barbara
name: Allen, Janet M.
name: Besser, Rachel E. J.
name: Boughton, Charlotte K.
name: Campbell, Fiona
name: Elleri, Daniela
name: Fuchs, Julia
name: Ghatak, Atrayee
name: Randell, Tabitha
name: Thankamony, Ajay
name: Trevelyan, Nicola
name: Wilinska, Malgorzata E.
name: Hovorka, Roman
name: Lawton, Julia
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Special Section: Disparities in Diabetes Technology
closed-loop
continuous glucose monitor
disparities
patient experiences
qualitative methods
type 1 diabetes

description: Background:: Closed-loop technology may help address health disparities experienced by adolescents, who are more likely to have suboptimal glycemic control than other age groups and, because of their age, find diabetes self-management particularly challenging. The CamAPS FX closed-loop has sought to address accessibility and usability issues reported by users of previous prototype systems. It comprises small components and a smartphone app used to: announce meal-time boluses, adjust (“boost” or “ease-off”) closed-loop insulin delivery, customize alarms, and review/share data. We explored how using the CamAPS FX platform influences adolescents’ self-management practices and everyday lives. Methods:: Eighteen adolescents were interviewed after having ≥6 months experience using the closed-loop platform. Data were analyzed thematically. Results:: Participants reported feeling less burdened and shackled by diabetes because closed-loop components were easier to carry/wear, finger-pricks were not required, the smartphone app provided a discreet and less stigmatizing way of managing diabetes in public, and they were able to customize alarms. Participants also reported checking and reviewing data more regularly, because they did so when using the smartphone for other reasons. Some reported challenges in school settings where use of personal phones was restricted. Participants highlighted how self-management practices were improved because they could easily review glucose data and adjust closed-loop insulin delivery using the “boost” and “ease-off” functions. Some described how using the system resulted in them forgetting about diabetes and neglecting certain tasks. Conclusions:: A closed-loop system with small components and control algorithm on a smartphone app can enhance usability and acceptability for adolescents and may help address the health-related disparities experienced by this age group. However, challenges can arise from using a medical app on a device which doubles as a smartphone. Trial registration:: Closed Loop From Onset in Type 1 Diabetes (CLOuD); NCT02871089; https://clinicaltrials.gov/ct2/show/NCT02871089
How does choice architecture influence attention and decision making?
Creators: name: Shi, Chaoyi
Publisher: name: University of British Columbia
Year: 2023

description: Choice architecture has a profound influence on human decision making, but the underlying cognitive mechanisms remain unclear. We propose that choice architecture guides visual attention to shape decision making. In a pre-registered experiment (N=646), participants were presented with two credit cards under different choice architecture conditions and were asked to choose the better card for themselves given their financial situation. We used a factorial between-subjects design with eight conditions: default (better card vs. worse card was pre-selected) x instructions (pre-selection was described as intentional vs. random) x presentation order (better card vs. worse card was presented on the left). Pre-registered analyses showed that participants paid more attention to the card when it was pre-selected than when not, and more likely to choose the pre-selected card. Participants also paid more attention to the better card and were more likely to choose it when it was presented on the left than on the right. However, instructions about the pre-selection had a limited impact on attention or choice. Exploratory analyses showed that attention mediated the effect of default and presentation order on choice, and choice also mediated the effect of default and presentation order on attention. These findings suggest that choice architecture guides visual attention to shape decision making. The current study provides new insights on the attentional mechanism of choice architecture, with implications for practitioners and policymakers on designing optimal choice architecture to aid decision making for consumers.
MPEC 2023-J166 : S/2004 S 48
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: S/2004 S 48

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Theory of acoustic-phonon assisted magnetotransport in 2D electron systems at large filling factors
Creators: name: Raichev, O. E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A microscopic theory of the phonon-induced resistance oscillations in weak perpendicular magnetic fields is presented. The calculations are based on the consideration of interaction of two-dimensional electrons with three-dimensional (bulk) acoustic phonons and take into account anisotropy of the phonon spectrum in cubic crystals. The magnetoresistance is calculated for [001]-grown GaAs quantum wells. The results are in agreement with available experimental data. Apart from the numerical results, analytical expressions for the oscillating part of magnetoresistance are obtained. These expressions are valid in the region of high-order magnetophonon resonances and describe the oscillating magnetoresistance determined by several groups of phonons polarized along certain high-symmetry directions.
description: 9 pages, 4 figures
title:   Optimization of Orally Bioavailable Inhibitors of Defective in Cullin Neddylation 1 (DCN-1)
Creators: name: Kovalic, Leah
Publisher: name: University of Kentucky Libraries
Year: 2023
Subjects: classificationCode: 3.5
subject: FOS: Other medical sciences

description: Ubiquitin (UB) and ubiquitin-like protein (UBL) pathways have emerged as important targets for oncology drug discovery based on the success of proteasome inhibitors (bortezomib or carfilzomib), E3 inhibitors, and the NEDD8 E1 inhibitor pevonedistat (MLN42924). Chemical inhibitors have also proven to be useful probes for identifying and dissecting multifactor UB and UBL regulatory networks. Toward this end, we have pursued approaches to target NEDD8 ligation to Cullins, through developing small molecule inhibitors of DCN1 (defective in Cullin Neddylation 1). DCN1 was discovered as a potentiating RBX1-dependent NEDD8-ligation, through recognizing the acetylated N-terminal methionine of the NEDD8 E2s UBE2M and UBE2F. The DCN1 gene was also discovered to undergo frequent chromosomal amplifications and associated with poor prognosis in squamous cell carcinomas and other cancers. To date, we have conducted a high-throughput screening campaign of ~500,000 compounds and have identified three unique chemical series for optimization.
description: © 2023 Leah Kovalic
Characterization of the Resonant Caustic Perturbation
Creators: name: Chung, Sun-Ju
Publisher: name: arXiv
Year: 2009
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Four of nine exoplanets found by microlensing were detected by the resonant caustic, which represents the merging of the planetary and central caustics at the position when the projected separation of a host star and a bounded planet is s~1. One of the resonant caustic lensing events, OGLE-2005-BLG-169, was a caustic-crossing high-magnification event with $A_{max} \sim$ 800 and the source star was much smaller than the caustic, nevertheless the perturbation was not obviously apparent on the light curve of the event. In this paper, we investigate the perturbation pattern of the resonant caustic to understand why the perturbations induced by the caustic do not leave strong traces on the light curves of high-magnification events despite a small source/caustic size ratio. From this study, we find that the regions with small-magnification-excess around the center of the resonant caustic are rather widely formed, and the event passing the small-excess region produces a high-magnification event with a weak perturbation that is small relative to the amplification caused by the star and thus does not noticeably appear on the light curve of the event. We also find that the positive excess of the inside edge of the resonant caustic and the negative excess inside the caustic become stronger and wider as $q$ increases, and thus the resonant caustic-crossing high-magnification events with the weak perturbation occur in the range of $q \leqslant 10^{-4}$. We determine the probability of the occurrence of events with the small excess $|ε| \leqslant 3 %$ in high-magnification events induced by a resonant caustic. As a result, we find that for the Earth-mass planets with a separation of ~ 2.5 AU, the resonant caustic high-magnification events with the weak perturbation can occur with a significant frequency.
description: 11 pages, 3 figures, 1 table, accepted for publication in ApJ
Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment
Creators: name: Pagano, Ester
name: Elias, Joshua E
name: Schneditz, Georg
name: Saveljeva, Svetlana
name: Holland, Lorraine M
name: Borrelli, Francesca
name: Karlsen, Tom H
name: Kaser, Arthur
name: Kaneider, Nicole
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: GI cancer
1506
2312
colorectal cancer
primary sclerosing cholangitis
angiogenesis
ulcerative colitis
receptor characterisation

description: Funder: NIHR Cambridge BRC
description: Objective: Primary sclerosing cholangitis (PSC) is in 70% of cases associated with inflammatory bowel disease. The hypermorphic T108M variant of the orphan G protein-coupled receptor GPR35 increases risk for PSC and ulcerative colitis (UC), conditions strongly predisposing for inflammation-associated liver and colon cancer. Lack of GPR35 reduces tumour numbers in mouse models of spontaneous and colitis associated cancer. The tumour microenvironment substantially determines tumour growth, and tumour-associated macrophages are crucial for neovascularisation. We aim to understand the role of the GPR35 pathway in the tumour microenvironment of spontaneous and colitis-associated colon cancers. Design: Mice lacking GPR35 on their macrophages underwent models of spontaneous colon cancer or colitis-associated cancer. The role of tumour-associated macrophages was then assessed in biochemical and functional assays. Results: Here, we show that GPR35 on macrophages is a potent amplifier of tumour growth by stimulating neoangiogenesis and tumour tissue remodelling. Deletion of Gpr35 in macrophages profoundly reduces tumour growth in inflammation-associated and spontaneous tumour models caused by mutant tumour suppressor adenomatous polyposis coli. Neoangiogenesis and matrix metalloproteinase activity is promoted by GPR35 via Na/K-ATPase-dependent ion pumping and Src activation, and is selectively inhibited by a GPR35-specific pepducin. Supernatants from human inducible-pluripotent-stem-cell derived macrophages carrying the UC and PSC risk variant stimulate tube formation by enhancing the release of angiogenic factors. Conclusions: Activation of the GPR35 pathway promotes tumour growth via two separate routes, by directly augmenting proliferation in epithelial cells that express the receptor, and by coordinating macrophages’ ability to create a tumour-permissive environment.
Additional file 1 of Hospital factor and prognosis of COVID-19 in New York City, the United States of America: insights from a retrospective cohort study
Creators: name: Takahashi, Mai
name: Egorova, Natalia N.
name: Iwagami, Masao
name: Kuno, Toshiki
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1: Supplemental Lists 1. The dependent variables to create propensity score for inverse probability treatment weight analysis to adjust hospital factors. Supplemental Lists 2. The dependent variables to create propensity score between patients hospitalized in community hospitals versus transfer patients. Supplemental Table 1. In hospital mortality, rates of ICU admission and intubation among patients admitted to teaching, community hospitals and transferred from community to teaching hospitals. Supplemental Table 2. In hospital mortality stratified by race. Supplemental Table 3. Age information of patients admitted to teaching, community hospitals and transferred from community to teaching hospital stratified by race. Supplemental Figure 1. Standardized mean difference in each comparison after inverse probability treatment weight adjustments. Supplemental Figure 2. Standardized mean difference after IPTW adjustments, transfer versus community hospitals.
Composite CaWO4 Detectors for the CRESST-II Experiment
Creators: name: Kiefer, M.
name: Angloher, G.
name: Bauer, M.
name: Bavykina, I.
name: Bento, A.
name: Brown, A.
name: Bucci, C.
name: Ciemniak, C.
name: Coppi, C.
name: Deuter, G.
name: von Feilitzsch, F.
name: Hauff, D.
name: Henry, S.
name: Huff, P.
name: Imber, J.
name: Ingleby, S.
name: Isaila, C.
name: Jochum, J.
name: Kimmerle, M.
name: Kraus, H.
name: Lanfranchi, J. -C.
name: Lang, R. F.
name: Malek, M.
name: McGowan, R.
name: Mikhailik, V. B.
name: Pantic, E.
name: Petricca, F.
name: Pfister, S.
name: Potzel, W.
name: Pröbst, F.
name: Roth, S.
name: Rottler, K.
name: Sailer, C.
name: Schäffner, K.
name: Schmaler, J.
name: Scholl, S.
name: Seidel, W.
name: Stodolsky, L.
name: Tolhurst, A. J. B.
name: Usherov, I.
name: Westphal, W.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: CRESST-II, standing for Cryogenic Rare Events Search with Superconducting Thermometers phase II, is an experiment searching for Dark Matter. In the LNGS facility in Gran Sasso, Italy, a cryogenic detector setup is operated in order to detect WIMPs by elastic scattering off nuclei, generating phononic lattice excitations and scintillation light. The thermometers used in the experiment consist of a tungsten thin-film structure evaporated onto the CaWO4 absorber crystal. The process of evaporation causes a decrease in the scintillation light output. This, together with the need of a big-scale detector production for the upcoming EURECA experiment lead to investigations for producing thermometers on smaller crystals which are glued onto the absorber crystal. In our Run 31 we tested composite detectors for the first time in the Gran Sasso setup. They seem to produce higher light yields as hoped and could provide an additional time based discrimination mechanism for low light yield clamp events.
description: Proceedings of the Thirteenth International Workshop on Low Temperature Detectors 4 pages, 9 figures
The n-body problem in General Relativity up to the second post-Newtonian order from perturbative field theory
Creators: name: Chu, Yi-Zen
Publisher: name: arXiv
Year: 2008
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Motivated by experimental probes of general relativity, we adopt methods from perturbative (quantum) field theory to compute, up to certain integrals, the effective lagrangian for its n-body problem. Perturbation theory is performed about a background Minkowski spacetime to O[(v/c)^4] beyond Newtonian gravity, where v is the typical speed of these n particles in their center of energy frame. For the specific case of the 2 body problem, the major efforts underway to measure gravitational waves produced by in-spiraling compact astrophysical binaries require their gravitational interactions to be computed beyond the currently known O[(v/c)^7]. We argue that such higher order post-Newtonian calculations must be automated for these field theoretic methods to be applied successfully to achieve this goal. In view of this, we outline an algorithm that would in principle generate the relevant Feynman diagrams to an arbitrary order in v/c and take steps to develop the necessary software. The Feynman diagrams contributing to the n-body effective action at O[(v/c)^6] beyond Newton are derived.
description: 39 pages. The Mathematica code used in this paper can be found at http://www.stargazing.net/yizen/PN.html Version 2: Slight re-wording of section on removal of accelerations in 2 PN lagrangian; comments added in conclusion; and typographical errors fixed. Article is similar to that published in PRD
Manufacturing Capability of Micro-Transfer Printing
Creators: name: Gomez, David
name: Moore, Tanya
name: Meitl, Matthew A.
name: Bonafede, Salvatore
name: Pearson, Andrew
name: Ghosal, Kanchan
name: Raymond, Brook
name: Radauscher, Erich
name: Kneeburg, David
name: Roe, Julia
name: Fecioru, Alin
name: Kelleher, Steven
name: Trindade, Antonio Jose
name: Bower, Christopher A.
Publisher: name: Zenodo
Year: 2019

description: Micro-Transfer printing is a mass transfer process that provides fast and precise assembly of micro-components onto non-native substrates. The process was originally conceived at the University of Illinois [1, 2], and has been developed at X-Celeprint. The process involves the fabrication of retrievable micro-components, elastomer stamp retrieval and transfer-printing of the micro-components to a non-native substrate and finally the interconnection [3]. With this process a large array of micro-components can be transferred at one time with an accuracy of +/- 1.5um 3 sigma and transfer yields exceeding 99%.
Origin of the X-rays and Possible GeV-TeV Emission from the Western Hot Spot Of Pictor A
Creators: name: Zhang, Jin
name: Bai, J. M.
name: Chen, Liang
name: Yang, Xian
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Pictor A is a nearby Fanaroff-Riley class II (FR II) radio galaxy with a bright hot spot, the western hot spot. Observation of high polarization in the optical emission of the hot spot indicates that the optical emission could be synchrotron radiation of relativistic electrons in the hot spot. These electrons may be able to produce high energy gamma-ray photons through inverse Compton (IC) scattering. We use single-zone and multi-zone synchrotron + synchrotron-self-Compton (SSC) models to fit the observed spectral energy distribution (SED) from the radio to the X-ray band of the hot spot. Our esults show that in the case of a much weaker magnetic field strength than the equipartition magnetic field, both the single-zone and multi-zone models can fit the SED, but the multi-zone model significantly improves the fit. The two models predict the hot spot as a GeV-TeV source, which might be marginally detectable with Fermi/LAT and HESS. The inverse Compton scattering of cosmic microwave background (IC/CMB) is also considered, but its contribution to GeV-TeV emission is negligible. Note that under the equipartition condition, the SED can also be fit with the multi-zone model, but the predicted flux at 10^22 Hz is too weak to be detectable. The detection of TeV gamma-rays from this FR II radio galaxy, if confirmed, would establish a new subclass of extragalactic source in this energy regime since most of the AGNs detected to date at TeV energies are high-energy-peaked BL Lac objects.
description: 15 pages, 3 figures, accepted for publication in ApJ
Additional file 1 of The prevalence of chronic medication therapy problems and pharmacists’ interventions among hospitalized perioperative patients: a retrospective observational study
Creators: name: Cheng, Hai-Ting
name: Zhao, Ming
name: Liu, Hong-Tao
name: Shen, Guo-Liang
name: Zhao, Ting
name: Feng, Zhi-En
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: Additional file 1.
MPEC 2023-J167 : S/2020 S 8
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: S/2020 S 8

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Three-Point Correlations in f(R) Models of Gravity
Creators: name: Borisov, Alex
name: Jain, Bhuvnesh
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Modifications of general relativity provide an alternative explanation to dark energy for the observed acceleration of the universe. We calculate quasilinear effects in the growth of structure in f(R) models of gravity using perturbation theory. We find significant deviations in the bispectrum that depend on cosmic time, length scale and triangle shape. However the deviations in the reduced bispectrum Q for f(R) models are at the percent level, much smaller than the deviations in the bispectrum itself. This implies that three-point correlations can be predicted to a good approximation simply by using the modified linear growth factor in the standard gravity formalism. Our results suggest that gravitational clustering in the weakly nonlinear regime is not fundamentally altered, at least for a class of gravity theories that are well described in the Newtonian regime by the parameters G_eff and Phi/Psi. This approximate universality was also seen in the N-body simulation measurements of the power spectrum by Stabenau and Jain (2006), and in other recent studies based on simulations. Thus predictions for such modified gravity models in the regime relevant to large-scale structure observations may be less daunting than expected on first principles. We discuss the caveats that apply to such predictions.
description: 10 pages, 7 figures, Submitted to PRD
Entropic origin of stress correlations in granular materials
Creators: name: Lois, Gregg
name: Zhang, Jie
name: Majmudar, Trushant S.
name: Henkes, Silke
name: Chakraborty, Bulbul
name: O'Hern, Corey S.
name: Behringer, Robert P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We study the response of granular materials to external stress using experiment, simulation, and theory. We derive an entropic, Ginzburg-Landau functional that enforces mechanical stability and positivity of contact forces. In this framework, the elastic moduli depend only on the applied stress. A combination of this feature and the positivity constraint leads to stress correlations whose shape and magnitude are extremely sensitive to the applied stress. The predictions from the theory describe the stress correlations for both simulations and experiments semiquantitatively.
description: 4 pages, 3 figures
Paludicola albifrons Boul.
Creators: name: Müller, F
Publisher: name: Zenodo
Year: 1885
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Amphibia
Anura
Leptodactylidae
Paludicola

description: * Paludicola albifrons Boul. cat.
Taguara v. F M. [5]
description: Published as part of Müller, F, 1885, Vierter Nachtrag zum Katalogder herpetologischen Sammlung des Basler Museums, pp. 668-717 in Verhandlungen der Naturforschenden Gesellschaft in Basel. 7 (3) on page 673, DOI: 10.5962/bhl.part.2388, http://zenodo.org/record/15183591
Balanced Tripartite Entanglement, the Alternating Group A4 and the Lie Algebra $sl(3,C) \oplus u(1)$
Creators: name: Planat, Michel
name: Levay, Peter
name: Saniga, Metod
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mathematical Physics (math-ph)
subject: Group Theory (math.GR)
subject: Representation Theory (math.RT)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We discuss three important classes of three-qubit entangled states and their encoding into quantum gates, finite groups and Lie algebras. States of the GHZ and W-type correspond to pure tripartite and bipartite entanglement, respectively. We introduce another generic class B of three-qubit states, that have balanced entanglement over two and three parties. We show how to realize the largest cristallographic group $W(E_8)$ in terms of three-qubit gates (with real entries) encoding states of type GHZ or W [M. Planat, {\it Clifford group dipoles and the enactment of Weyl/Coxeter group $W(E_8)$ by entangling gates}, Preprint 0904.3691 (quant-ph)]. Then, we describe a peculiar "condensation" of $W(E_8)$ into the four-letter alternating group $A_4$, obtained from a chain of maximal subgroups. Group $A_4$ is realized from two B-type generators and found to correspond to the Lie algebra $sl(3,\mathbb{C})\oplus u(1)$. Possible applications of our findings to particle physics and the structure of genetic code are also mentioned.
description: 14 pages
title: With mental health and wellbeing in mind
Creators: name: McCollam, Allyson
Publisher: name: Strathprints - University of Strathclyde
Year: 2009

description: This paper is based on work undertaken on behalf of the Scottish Development Centre for Mental Health and it explores key challenges in addressing the mental health needs of children and young people who are looked after away from home. It considers some models of working that show promise in building bridges between activities to promote good mental health for all such children, as well as highlighting activities that focus on assessment, care and treatment for those who require such intervention.
title: Mindful care : the pilot of a new mental health service for young people who are looked after away from home in Moray
Creators: name: Makinson, Jenny
name: Wiles, Christopher
name: Jones, Debbie
name: Erskine, Sheila
Publisher: name: Strathprints - University of Strathclyde
Year: 2009

description: It is well documented that children and young people who are looked after away from home have significantly high rates of mental health problems coupled with poor psychological adjustment and general levels of emotional wellbeing (McCann et al., 1996; Minnis & Devine, 2001; Minnis et al., 2001; Hill & Watkins, 2003; Meltzer et al., 2004; Rodrigues, 2004; Ford et al., 2007). A range of conduct, emotional and hyperkinetic disorders appear most common in this population, and co-morbidity rates are noticeably high (Meltzer et al., 2004). Furthermore, only a small proportion of this at-risk population is likely to be accessing Child and Adolescent Mental Health Services (CAMHS) (Dimigen et al., 1999). Barriers to successful CAMHS input occur at several stages within the process, from identification and referral of mental health problems through to the engagement of the young person and effective interventions for their specific constellation of behaviours and symptoms (Blower et al., 2004; Mount, Lister & Bennun, 2004).
Additional file 7 of Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis
Creators: name: Salazar, Ivan L.
name: Lourenço, Ana S. T.
name: Manadas, Bruno
name: Baldeiras, Inês
name: Ferreira, Cláudia
name: Teixeira, Anabela Claro
name: Mendes, Vera M.
name: Novo, Ana Margarida
name: Machado, Rita
name: Batista, Sónia
name: Macário, Maria do Carmo
name: Grãos, Mário
name: Sousa, Lívia
name: Saraiva, Maria João
name: Pais, Alberto A. C. C.
name: Duarte, Carlos B.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 7. Table S1- Principal component analysis considering the results obtained in the proteomics analysis of samples collected from patients with Relapse-Remitting Multiple Sclerosis (RRMS) and other inflammatory diseases of the CNS (INF). Table S2- Principal component analysis considering the results obtained in the proteomics analysis of samples collected from patients with Relapse-Remitting Multiple Sclerosis (RRMS) and non-inflammatory diseases of the CNS (N-INF). Table S3- Protein spots showing a differential distribution between Relapse-Remitting Multiple Sclerosis (RRMS) and other inflammatory diseases of the CNS (INF). Table S4- Protein spots from CSF samples showing a differential distribution between Relapse-Remitting Multiple Sclerosis (RRMS) and non-inflammatory diseases of CNS (N-INF). Table S5- Protein spots showing a significant change in abundance when comparing CSF samples from relapse-remitting multiple sclerosis vs. other inflammatory and non-inflammatory diseases of the CNS (control) as a single group. Table S6- Protein Identification from selected 2D-PAGE spots (SSP) by LC-MS/MS. Table S7- Eigenvalues for the proteins in the study in the CSF dataset. The most relevant proteins are underlined and correspond to eigenvalues superior to 1. Table S8- Loadings of the PCA for CSF scaled data. Loadings with an absolute value ≥ 0.40 are underlined. Table S9- Means of the clusters present in the HCA dendrogram representing the similarity between the protein content in the CSF of the three groups of patients, as determined by ELISA.
title: The contribution of Music Therapy to the emotional wellbeing of children in residential child care
Creators: name: Vuliamy, Aby
Publisher: name: Strathprints - University of Strathclyde
Year: 2009

description: I was recently surprised to discover that there is only a small handful of music therapists employed within Scottish residential child care. There also appears to be a significant gap in the international literature with regard to music therapy in residential child care. I believe that the use of music therapy in residential child care can enhance wellbeing. This paper will review seven issues that I find particularly pertinent to music therapy for children who are looked after away from home. I will use case study examples from two young people with whom I have worked, reinforced with theoretical references, in order to show how these issues influence music therapy in residential child care.
D2.4 – Dissemination results 2
Creators: name: Fernandez-Manjon, Baltasar
name: Alonso-Fernandez, Cristina
name: Perez-Colado, Ivan Jose
name: Freire, Manuel
name: Martinez-Ortiz, Ivan
name: Stefan, Antoniu
Publisher: name: Zenodo
Year: 2019
Subjects: dissemination
communication
impact

description: This document collects the KPIs on the dissemination activities carried out during the totality of the project, building up from the previous deliverable which stated the results of the first 18 months of the project (D2.3). These results include articles published in high impact scientific journals, papers presented at international conferences, workshops and other dissemination events. The dissemination results are compared against the KPIs established in T2.1.

The current results show that the project has exceeded the expected results from the DoA and that all the main KPIs have been successfully achieved. In particular, the project has derived more than 60 high-level publications (conference papers, journal papers and book sections), being part of more than 65 international and national conferences, with partners giving BEACONING related presentations at more than 45 events.

Additionally, we have identified a set of success cases (described in full detail in Appendix 1) in 7 different countries and contexts (schools, colleges, education fairs and labs, conferences), and covering different stakeholders (teachers, students, business developers, managers, educational authorities) to prove impact of the project in a variety of settings. On these success cases, a total of around 13,500 people were directly reached or involved in BEACONING

activities, including the Cross-European Location-Based event where 450 users participated across 17 cities.
Study of the decay K+ => pi+,nu,nubar in the momentum region 140
Creators: name: E949 Collaboration
name: Artamonov, A. V.
name: Bassalleck, B.
name: Bhuyan, B.
name: Blackmore, E. W.
name: Bryman, D. A.
name: Chen, S.
name: Chiang, I-H.
name: Christidi, I. -A.
name: Cooper, P. S.
name: Diwan, M. V.
name: Frank, J. S.
name: Fujiwara, T.
name: Hu, J.
name: Ives, J.
name: Jaffe, D. E.
name: Kabe, S.
name: Kettell, S. H.
name: Khabibullin, M. M.
name: Khotjantsev, A. N.
name: Kitching, P.
name: Kobayashi, M.
name: Komatsubara, T. K.
name: Konaka, A.
name: Kozhevnikov, A. P.
name: Kudenko, Yu. G.
name: Kushnirenko, A.
name: Landsberg, L. G.
name: Lewis, B.
name: Li, K. K.
name: Littenberg, L. S.
name: Macdonald, J. A.
name: Mildenberger, J.
name: Mineev, O. V.
name: Miyajima, M.
name: Mizouchi, K.
name: Mukhin, V. A.
name: Muramatsu, N.
name: Nakano, T.
name: Nomachi, M.
name: Nomura, T.
name: Numao, T.
name: Obraztsov, V. F.
name: Omata, K.
name: Patalakha, D. I.
name: Petrenko, S. V.
name: Poutissou, R.
name: Ramberg, E. J.
name: Redlinger, G.
name: Sato, T.
name: Sekiguchi, T.
name: Shinkawa, T.
name: Strand, R. C.
name: Sugimoto, S.
name: Tamagawa, Y.
name: Tschirhart, R.
name: Tsunemi, T.
name: Vavilov, D. V.
name: Viren, B.
name: Wang, Zhe
name: Yershov, N. V.
name: Yoshimura, Y.
name: Yoshioka, T.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Experiment E949 at Brookhaven National Laboratory has observed three new events consistent with the decay K+ => pi+,nu,nubar in the pion momentum region 140 < P_pi < 199 MeV/c in an exposure of 1.71e12 stopped kaons with an estimated total background of 0.93+-0.17(stat.)+0.32-0.24(syst.) events. This brings the total number of observed K+ => pi+,nu,nubar events to seven. Combining this observation with previous results, assuming the pion spectrum predicted by the standard model, results in a branching ratio of (1.73+1.15-1.05)e-10. An interpretation of the results for alternative models of the decay K^ => pi+,nothing is also presented.
description: Submitted to Phys.Rev. D
Star Formation at Molecular Cloud Scales: An Observational Perspective
Creators: name: Megeath, Tom
Publisher: name: Zenodo
Year: 2021
Subjects: Molecular Clouds
YSOs
Star Formation

description: An observationally grounded understanding of the formation and evolution of molecular clouds, and the connection between cloud structure and star formation, are necessary for determining how multi-parsec and stellar scale processes regulate the formation of stars in galaxies. Focusing on observations of nearby clouds, I will overview key steps toward unravelling these processes. These include an assessment of the role of filaments, ridges and hubs in star and cluster formation, the implications of recently discovered star-formation laws at cloud scales, and efforts to measure the effect of stellar feedback. I will conclude with a brief discussion of how observations of nearby clouds, combined with surveys of distant clouds in our galaxy and others, can fill in gaps in our understanding.
On the generalized continuity equation
Creators: name: Arbab, Arbab I.
name: Widatallah, Hisham. M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: A generalized continuity equation extending the ordinary continuity equation has been found using quanternions. It is shown to be compatible with Dirac, Schrodinger, Klein-Gordon and diffusion equations. This generalized equation is Lorentz invariant. The transport properties of electrons are found to be governed by Schrodinger-like equation and not by the diffusion equation.
description: 9 Latex pages, no figures
Additional file 1 of Prevalence of autoantibodies in patients with juvenile idiopathic arthritis: results from the German inception cohort ICON-JIA
Creators: name: Schulz, Caroline
name: Fuehner, Sabrina
name: Schlüter, Bernhard
name: Fobker, Manfred
name: Sengler, Claudia
name: Klotsche, Jens
name: Niewerth, Martina
name: Minden, Kirsten
name: Foell, Dirk
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Suppl Table S1. ANA IFT results in patients with positive CTD screen
The glass transition and crystallization kinetic studies on BaNaB9O15 glasses
Creators: name: Vaish, Rahul
name: Varma, K. B. R.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: Transparent glasses of BaNaB9O15 (BNBO) were fabricated via the conventional melt-quenching technique. The amorphous and the glassy nature of the as-quenched samples were respectively, confirmed by X-ray powder diffraction (XRD) and differential scanning calorimetry (DSC). The glass transition and crystallization parameters were evaluated under non-isothermal conditions using DSC. The correlation between the heating rate dependent glass transition and the crystallization temperatures was discussed and deduced the Kauzmann temperature for BNBO glass-plates and powdered samples. The values of the Kauzmann temperature for the plates and powdered samples were 776 K and 768 K, respectively. Approximation-free method was used to evaluate the crystallization kinetic parameters for the BNBO glass samples. The effect of the sample thickness on the crystallization kinetics of BNBO glasses was also investigated.
description: 23 pages, 12 figures
XMM-Newton discovery of 2.6 s pulsations in the soft gamma-ray repeater SGR 1627-41
Creators: name: Esposito, P.
name: Tiengo, A.
name: Mereghetti, S.
name: Israel, G. L.
name: De Luca, A.
name: Götz, D.
name: Rea, N.
name: Turolla, R.
name: Zane, S.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: After nearly a decade of quiescence, the soft gamma-ray repeater SGR 1627-41 reactivated on 2008 May 28 with a bursting episode followed by a slowly decaying enhancement of its persistent emission. To search for the still unknown spin period of this SGR taking advantage of its high flux state, we performed on 2008 September 27-28 a 120 ks long X-ray observation with the XMM-Newton satellite. Pulsations with P = 2.594578(6) s were detected at a higher than 6-sigma confidence level, with a double-peaked pulse profile. The pulsed fraction in the 2-12 keV range is 19% +/- 3% and 24% +/- 3% for the fundamental and the second harmonic, respectively. The observed 2-10 keV flux is 3.4E-13 erg/cm^2/s, still a factor of ~ 5 above the quiescent pre-burst-activation level, and the spectrum is well fitted by an absorbed power law plus blackbody model (photon index Gamma = 0.6, blackbody temperature kT = 0.5 keV, and absorption nH = 1.2E+23 cm^-2). We also detected a shell of diffuse soft X-ray emission which is likely associated with the young supernova remnant G337.0-0.1.
description: Minor changes to match the final version (to appear in The Astrophysical Journal Letters). 5 pages in emulate-apj style, 1 table, 4 figures (1 color)
Exchange-correlation enhancement of the Lande-g* factor in integer quantized Hall plateaus
Creators: name: Bilgec, G.
name: Toffoli, H. Ustunel
name: Siddiki, A.
name: Sokmen, I.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the emergent role of many-body effects on a two dimensional electron gas (2DEG) within the Thomas-Fermi-Poisson approximation, including both the exchange and correlation interactions in the presence of a strong perpendicular magnetic field. It is shown that, the indirect interactions widen the odd-integer incompressible strips spatially, whereas the even-integer filling factors almost remain unaffected.
description: 8 pages,4 figures
Regional cerebral metabolic rate of oxygen and levels of respiratory support in preterm neonates
Creators: name: Zhu, Chen Shuang
Publisher: name: University of British Columbia
Year: 2023

description: Background: Preterm birth is associated with a higher rate of brain injury and neurodevelopmental delays in children. The brain is dependent on oxidative metabolism of glucose to meet its significant energy requirements. Understanding the cerebral metabolic rate of oxygen (CMRO₂) and how it is affected by ventilation in the neonatal population is crucial to the advancement of neonatal medicine. This study aims to assess the feasibility of quantifying CMRO₂ and cerebral blood flow (CBF) using magnetic resonance imaging (MRI) in preterm infants at term equivalent age (TEA) and to determine how various ventilatory support may affect CMRO₂. We hypothesized that increased time on mechanical ventilation would be negatively associated with CMRO2 and CBF levels in preterm neonates at TEA. Methods: Very preterm neonates (n=19) born <32 weeks gestational age were recruited in the NICU and scanned at TEA. The scanning sequence consisted of a 3D T1-weighted, 3D T2-weighted, arterial spin labeling (ASL), and susceptibility weighted imaging (SWI) scan. CBF maps were calculated with ASL, and SWI was used to create quantitative susceptibility maps (QSM) to calculate the cerebral venous oxygen saturation (CSvO₂). Clinical data was acquired from the Canadian Neonatal Network (CNN) database and chart review. Results: Average global CMRO₂ was 28.49±3.29 µmol/100g/min (mean±SD), consistent with values of CMRO₂ reported in the literature falling within the range of 25-45 µmol/100g/min. The average global CBF was 13.96±4.22 mL/100g/min. CMRO₂ and CBF were found to be positively correlated with days on noninvasive ventilation and negatively correlated with days on room air. CBF was also positively correlated with total time on ventilation. Conclusion: We demonstrated the feasibility of noninvasive quantification of CMRO2 and CBF using MRI in very preterm neonates at TEA. The levels of CMRO2 and CBF found in these infants were consistent with values previously reported for neonates of similar sample populations. Higher CMRO2 values with longer durations of noninvasive ventilation may indicate better health outcomes. Previous literature has shown no adverse effects of prolonged noninvasive ventilation, suggesting that invasive ventilation should be replaced by noninvasive ventilation when possible.
Business Ethics and the Sustainability of Businesses in Post Covid-19 in Nigeria.pdf
Creators: name: Obo, Ekpenyong  Bassey
Publisher: name: figshare
Year: 2023
Subjects: Commercial services not elsewhere classified

description: This paper examines the position of business ethics and the crisis impose on businesses by Covid-19 pandemic. It argues that to achieve a sustainable business today, the ethical behaviour of the organizations and their employees must be thoroughly addressed. The paper reviews the challenges of business ethics in business organizations, as well as interventional framework for adopting a responsible business conduct. It further proposes survival approach to business organizations and leaders of business on how to take their business through a sustainable recovery. KEYWORDS: ethics, business ethics, ethical behaviour, business sustainability.
title: Electronic Literature as Digital Humanities: An Introduction
Creators: name: Grigar, Dene
Publisher: name: Electronic Book Review
Year: 2021

description: Electronic Literature as Digital Humanities: Contexts, Forms & Practices is a volume of essays co-edited by Dene Grigar and James O’Sullivan that provides a detailed account of born-digital literature by artists and scholars who have contributed to its birth and evolution. Rather than offering a prescriptive definition of electronic literature, this book takes an ontological approach through descriptive exploration, treating electronic literature from the perspective of the digital humanities (DH)––that is, as an area of scholarship and practice that exists at the juncture between the literary and the algorithmic.
How Is the Wheat Agreement Working?
Creators: name: Office Of Foreign Agricultural Relations
name: Production And Marketing Administration
name: Office Of Foreign Agricultural Relations
name: Production And Marketing Administration
Publisher: name: Unknown
Year: 1952
Subjects: Agricultural and Food Policy
Crop Production/Industries
Demand and Price Analysis
International Relations/Trade

description: Excerpt from the report: The International Wheat Agreement is now in its third year. Since it runs for only 4 years, it will expire in another year unless it is renewed. This brings up the question: How has it been working ? Wheat farmers and many other people have an important interest in the answer. Since World War II, one-third of our United States wheat has gone to foreign countries. This has been the average annual product of 24 million acres. To put it another way, the wheat we have shipped abroad in recent years has been nearly equal to all the wheat grown during those years in Nebraska, Kansas, Oklahoma, and Texas. Without that foreign market, our wheat farmers would have to cut their production drastically. Elevator operators, millers, exporters, transportation companies, and others who handle wheat also are concerned with the future of the United States in the world wheat market.