Setting research priorities to improve global newborn health and prevent stillbirths by 2025
Creators: name: Paul, Vinod
name: Zuniga, Isabel
name: Bose, Carl
name: English, Mike
name: Williams, Sarah L.A.
name: Mol, Ben Willem J.
name: Poets, Christian
name: Nacul, Luis Carlos
name: Souza, Joao Paulo
name: Molyneux, Elizabeth
name: Zaidi, Anita
name: Islam, 
name: Luhanga, Richard
name: Corbett, Erica
name: Waiswa, Peter
name: Joshua, Martias Alice
name: Kramer, Michael S.
name: Clark, Robert
name: van Bel, Frank
name: McNamara, Patrick J.
name: Smith, Peter G.
name: Colbourn, Tim
name: Conde-Agudelo, Agustin
name: Marsh, David
name: Dilmen, Ugur
name: Esamai, Fabian
name: Soofi, Sajid
name: Deal, Carolyn
name: Khatoon, Soofia
name: Reddy, Uma M.
name: Das, Abhik
name: Lawintono, Laurensia
name: Wall, Stephen
name: Nakakeeto, Margaret
name: Osrin, David
name: Keenan, William
name: Kieler, Helle
name: Asiruddin, 
name: Benn, Christine S.
name: Lackritz, Eve M.
name: Tshefu, Antoinette
name: Black, Robert E.
name: Irgens, Lorentz
name: Lawn, Joy E.
name: Cheung, Po-Yin
name: Higgins, Rosemary D.
name: Bührer, Christoph
name: Sultana, Shahin
name: Ferriero, Donna M.
name: Bhattacharya, Sohinee
name: Homer, Caroline S.E.
name: Gray, Lauren Vestewig
name: Aryal, Dhana Raj
name: Aaby, Peter
name: de Graft-Johnson, Joseph
name: Rudan, Igor
name: Narayanan, Indira
name: Carlo, Wally
name: Zhong, Nanbert
name: Martines, José
name: Adhikari, Ramesh Kant
name: Lavender, Tina
name: Bahl, Rajiv
name: Hoque, 
name: Yoshida, Sachiyo
name: Bhandari, Vineet
name: Arifeen, Shams E.I.
name: Olusanya, Bolajoko
name: Czeizel, Andrew E.
name: Bhatnagar, Shinjini
name: Spong, Catherine Y.
name: Cousens, Simon
name: Cecatti, Jose Guilherme
name: Zhang, Yanfeng
name: Sayed, Rubayet
name: Santosham, Mathuram
name: Ambalavanan, Namasivayam
name: Wang, Wei
name: Schlabritz-Loutsevitch, Natalia E.
name: Wright, Linda
name: Singhal, Nalini
name: Bhutta, Zulfiqar A.
name: Hazir, Tabish
name: Gisore, Peter
name: Fall, Caroline
name: Engmann, Cyril
name: McMillan, Douglas
name: Deorari, Ashok
name: Mutabazi, Miriam
name: Blencowe, Hannah
name: Day, Louise Tina
name: Brown, Justin
name: Mukasa, 
name: Adam, Ishag
name: Smith, Mary Alice
name: Baqui, Abdullah
name: Barros, Aluisio J.D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: BackgroundIn 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013–2025.MethodsWe used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts.ResultsNine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour.ConclusionThese findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed.