cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
An efficient Cu-catalyzed microwave-assisted synthesis of diaryl sulfones
Creators: name: Nandi, Ganesh C.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: An efficient and microwave-assisted simple protocol for the synthesis of symmetrical/asymmetrical diaryl sulfones through the Cu(II)-catalyzed reaction of sodium salt of sulfinic acid with aryl boronic acid has been described. Various diaryl sulfones have been synthesized in very short reaction times with moderate to very good yields. Additionally, the method is also useful for the synthesis of aryl vinyl sulfones.
Synthesis of Triazolidines and Triazole Using DMAP
Creators: name: Devidas A. Mali
name: Telvekar, Vikas N.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: An efficient methodology has been developed for the synthesis of 1, 2, 4-triazolidine-3-thione and 3-ethoxy-5-phenyl-4H-1, 2, 4 triazole using N, N-dimethylpyridine-4-amine (DMAP). Aldehydes and thiosemicarbazide reacted in water at ambient temperature in presence of DMAP and provided corresponding products in good to moderate yield.
An efficient Cu-catalyzed microwave-assisted synthesis of diaryl sulfones
Creators: name: Nandi, Ganesh C.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: An efficient and microwave-assisted simple protocol for the synthesis of symmetrical/asymmetrical diaryl sulfones through the Cu(II)-catalyzed reaction of sodium salt of sulfinic acid with aryl boronic acid has been described. Various diaryl sulfones have been synthesized in very short reaction times with moderate to very good yields. Additionally, the method is also useful for the synthesis of aryl vinyl sulfones.
Efficient novel synthesis of pyrano[3,2-a]- and pyrazolo[4,3-a]-acridines
Creators: name: Satheeshkumar, Rajendran
name: Kaminsky, Werner
name: Prasad, Karnam Jayarampillai Rajendra
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: The synthesis of pyrano[3,2-a]acridines is presented, where 7-chloro-9-phenyl-2,3-dihydroacridin-4(1H)-one reacts with arylaldehydes and malononitrile in the presence of piperidine in ethanol, giving with high yield via a multicomponent method. Also a new synthesis of pyrazolo[4,3-a]acridines is reported, where 7-chloro-9-aryl-2,3-dihydroacridin-4(1H)-one on Claisen condensation with ethylformate followed by hydrazine hydrate treatment through the intermediate 7-chloro-4-hydroxy-9-aryl-1,2-dihydroacridin-3-carbaldehyde. The structures of newly synthesized compounds were deduced by spectroscopic techniques, elemental analysis, and single-crystal x-ray diffraction.
Amino acid catalyzed reactions. A facile route to some heteroarylbispyrazoles
Creators: name: Faryal Chaudhry
name: Naureen, Sadia
name: Ijaz, Fatima
name: Munawar, Munawar Ali
name: Misbahul Ain Khan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: This newly designed route assembled a pyrazole ring with an aldehydic functionality over another pyrazole moiety. Further, formyl group was exploited in different routes such as condensation reactions, imidazole and pyrimidone/thione synthesis. The present reactions were performed with glycine, a facile catalyst, and the results were compared well with those of conventional methods.
An Efficient Novel Synthesis of Pyrano[3,2-a]- and Pyrazolo[4,3-a]- Acridines
Creators: name: Satheeshkumar, Rajendran
name: Kaminsky, Werner
name: Prasad, Karnam Jayarampillai Rajendra
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: The synthesis of pyrano[3,2-a]acridines is presented, where 7-chloro-9-phenyl-2,3-dihydroacridin-4(1H)-one reacts with arylaldehydes and malononitrile in the presence of piperidine in ethanol, giving with high yield via Multicomponent method. Also a new synthesis of pyrazolo[4,3-a]acridines is reported, where 7-chloro-9-aryl-2,3-dihydroacridin-4(1H)-one on Claisen condensation with ethylformate followed by hydrazine hydrate treatment through the intermediate 7-chloro-4-hydroxy-9-aryl-1,2-dihydroacridin-3-carbaldehyde. The structures of newly synthesized compounds were deduced by spectroscopic techniques, elemental analysis and single-crystal x-ray diffraction.
A tRNA-derived fragment competes with mRNA for ribosome binding and regulates translation during stress
Creators: name: Gebetsberger, Jennifer
name: Wyss, Leander
name: Mleczko, Anna M.
name: Reuther, Julia
name: Polacek, Norbert
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Posttranscriptional processing of RNA molecules is a common strategy to enlarge the structural and functional repertoire of RNomes observed in all three domains of life. Fragmentation of RNA molecules of basically all functional classes has been reported to yield smaller non-protein coding RNAs (ncRNAs) that typically possess different roles compared to their parental transcripts. Here we show that a valine tRNA-derived fragment (Val-tRF) that is produced under certain stress conditions in the halophilic archaeon Haloferax volcanii is capable of binding to the small ribosomal subunit. As a consequence of Val-tRF binding messenger RNA is displaced from the initiation complex which results in global translation attenuation in vivo and in vitro. The fact that the archaeal Val-tRF also inhibits eukaryal as well as bacterial protein biosynthesis implies a functionally conserved mode of action. While tRFs and tRNA halves have been amply identified in recent RNA-seq project, Val-tRF described herein represents one of the first functionally characterized tRNA processing products to date.
Amino Acid Catalysed Reactions. A Facile Route to Some Heteroarylbispyrazoles
Creators: name: Faryal Chaudhry
name: Naureen, Sadia
name: Ijaz, Fatima
name: Munawar, Munawar Ali
name: Misbahul Ain Khan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: This newly designed route assembled a pyrazole ring with an aldehydic functionality over another pyrazole moiety. Further, formyl group was exploited in different routes such as condensation reactions, imidazole and pyrimidone/thione synthesis. The present reactions were carried out with glycine, a facile catalyst, and the results compared well with those of conventional methods.
LINE-1 methylation status in prostate cancer and non-neoplastic tissue adjacent to tumor in association with mortality
Creators: name: Fiano, Valentina
name: Zugna, Daniela
name: Grasso, Chiara
name: Trevisan, Morena
name: Delsedime, Luisa
name: Molinaro, Luca
name: Gillio-Tos, Anna
name: Merletti, Franco
name: Richiardi, Lorenzo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer

description: Aberrant DNA methylation seems to be associated with prostate cancer behavior. We investigated LINE-1 methylation in prostate cancer and non-neoplastic tissue adjacent to tumor (NTAT) in association with mortality from prostate cancer. We selected 157 prostate cancer patients with available NTAT from 2 cohorts of patients diagnosed between 1982–1988 and 1993–1996, followed up until 2010. An association between LINE-1 hypomethylation and prostate cancer mortality in tumor was suggested [hazard ratio per 5% decrease in LINE-1 methylation levels: 1.40, 95% confidence interval (CI): 0.95–2.01]. After stratification of the patients for Gleason score, the association was present only for those with a Gleason score of at least 8. Among these, low (<75%) vs. high (>80%) LINE-1 methylation was associated with a hazard ratio of 4.68 (95% CI: 1.03–21.34). LINE-1 methylation in the NTAT was not associated with prostate cancer mortality. Our results are consistent with the hypothesis that tumor tissue global hypomethylation may be a late event in prostate cancerogenesis and is associated with tumor progression.
Data Table of Pınarbaşı Bird Remains Primary Descriptions [Structured Data from Open Context]
Creators: name: Nerissa Russell
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Data Table of Pınarbaşı Bird Remains Primary Descriptions Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 150-data-table-of-pinarbasi-bird-remains-primary-descriptio.csv contains the tabular data content for this resource in a CSV format.
JSON: The 150-data-table-of-pinarbasi-bird-remains-primary-descriptio.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
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Data Governance Principles
Zooarchaeology Data Table for Northern Highland Archaeofaunas of Ecuador [Structured Data from Open Context]
Creators: name: Peter W Stahl
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Zooarchaeology Data Table for Northern Highland Archaeofaunas of Ecuador Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 154-zooarchaeology-data-table-for-northern-highland-archaeo.csv contains the tabular data content for this resource in a CSV format.
JSON: The 154-zooarchaeology-data-table-for-northern-highland-archaeo.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
title: Evaluation 2 projet TRAMED 2013
Creators: name: LabexMed
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019

description: Évaluation du projet TRAMED- Les problématiques du travail dans l'espace méditerranéen en crise", réalisée en 2013.
Jean-Paul Claverie (conseiller de mécénat du groupe LVMH)
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (1 page).
Multidrug and toxin extrusion protein 1-mediated interaction of metformin and Scutellariae radix in rats
Creators: name: Sreymom Yim
name: You, Byoung Hoon
name: Hee-Sung Chae
name: Young-Won Chin
name: Hojun Kim
name: Choi, Han Seok
name: Choi, Young Hee
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Inorganic Chemistry
subject: 60506 Virology

description: 1. The metformin and Scutellariae radix extract (SB) combination has been previously reported to enhance anti-diabetic activity. Considering that organic cation transporters (OCTs) and multi-drug and toxin extrusion proteins (MATEs) in the liver and kidney are determinant factors on hepatic distribution and renal clearance of metformin, the effects of SB on OCT or MATE-mediated systemic exposure of metformin as well as on glucose tolerance and hypoglycemia were examined. 2. Although SB inhibited metformin uptake through human transporters OCT1 and MATE1 in vitro, the systemic exposures of metformin in vivo rats were not altered after metformin treatment with and without SB due to unchanged renal excretion of metformin. 3. However, 28-day metformin treatment with SB decreased the mRNA level of hepatic MATE1 in rats, resulting in reduced biliary excretion of metformin and thereby higher concentration of metformin in the liver. In addition, in rats with 28-day metformin treatment with SB, glucose tolerance and plasma lactate level were enhanced, while hypoglycemia was not detected. 4. Thus in rats, intervention of SB on transporter-mediated metformin transportation partially improves glucose tolerance without hypoglycemia and increases hepatic distribution of metformin. Also the further investigations in humans are required to clarify the relevance of these findings to the clinical significance.
Decisional needs and support interventions to promote patient engagement in healthcare decisions in forensic mental health: a scoping review protocol
Creators: name: Canning, Christopher
name: Jull, Janet
name: Allen, Kristy
name: Hiebert, Melissa
name: Junes, Stephanie
name: Hilton, N. Zoe
name: Rondinone, Emily
name: Bullock, Heather
name: Zhao, Junqiang
name: Charlebois, Alex
name: Duquette, Matthew
name: Achal Mishra
name: Zisman-Ilani, Yaara
name: Waddell, Andrea
name: Tomlin, Jack
name: Bolshaw-Walker, Helen
name: Felipe, Kim
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Medicine and Health Sciences

description: This study aims to examine the research progress of patient engagement in healthcare decisions in forensic mental health settings through a scoping review of literature. Specifically, our objectives are to: 1) Identify decisional needs of patients in forensic mental health settings 2) Examine decision support interventions used to address decisional needs in forensic programs 3) Identify reported outcomes for decision support interventions 4) Synthesize health professionals' and other stakeholders’ attitudes, and perceived barriers and facilitators towards patient engagement (if reported).
Zooarchaeology Data Table for Early Holocene Las Vegas, Ecuador [Structured Data from Open Context]
Creators: name: Peter W Stahl
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Zooarchaeology Data Table for Early Holocene Las Vegas, Ecuador Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 151-zooarchaeology-data-table-for-early-holocene-las-vegas.csv contains the tabular data content for this resource in a CSV format.
JSON: The 151-zooarchaeology-data-table-for-early-holocene-las-vegas.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
"Navigating Breastfeeding Challenges: Essential Nursing Support Strategies for Maternal and Infant Well-being"
Creators: name: Reena Mathew, Reena Mathew
Publisher: name: Zenodo
Year: 2024

description: Breastfeeding is widely regarded as the gold standard for infant nutrition due to its unparalleled health benefits for both infants and mothers. Despite its importance, many women encounter substantial physical, psychological, and social challenges that can hinder successful breastfeeding. These challenges contribute to early cessation or suboptimal breastfeeding practices, with negative consequences for both maternal and infant health. Nurses play a pivotal role in identifying and addressing these challenges through individualized education, clinical interventions, and emotional support. This article explores the common challenges faced by breastfeeding mothers and provides evidence-based nursing strategies aimed at improving breastfeeding outcomes and experiences
Data table of animal bones found in Vatnsvik, lake Þingvallavatn, Iceland [Structured Data from Open Context]
Creators: name: Albína H Pálsdóttir
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Data table of animal bones found in Vatnsvik, lake Þingvallavatn, Iceland Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 144-data-table-of-animal-bones-found-in-vatnsvik-lake-thing.csv contains the tabular data content for this resource in a CSV format.
JSON: The 144-data-table-of-animal-bones-found-in-vatnsvik-lake-thing.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
Efflux as a mechanism of antimicrobial drug resistance in clinical relevant microorganisms: the role of efflux inhibitors
Creators: name: Willers, Clarissa
name: Wentzel, Johannes Frederik
name: Lissinda Hester Du Plessis
name: Chrisna Gouws
name: Josias Hendrik Hamman
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Introduction: Microbial resistance against antibiotics is a serious threat to the effective treatment of infectious diseases. Several mechanisms exist through which microorganisms can develop resistance against antimicrobial drugs, of which the overexpression of genes to produce efflux pumps is a major concern. Several efflux transporters have been identified in microorganisms, which infer resistance against specific antibiotics and even multidrug resistance. Areas covered: This paper focuses on microbial resistance against antibiotics by means of the mechanism of efflux and gives a critical overview of studies conducted to overcome this problem by combining efflux pump inhibitors with antibiotics. Information was obtained from a literature search done with MEDLINE, Pubmed, Scopus, ScienceDirect, OneSearch and EBSCO host. Expert opinion: Efflux as a mechanism of multidrug resistance has presented a platform for improved efficacy against resistant microorganisms by co-administration of efflux pump inhibitors with antimicrobial agents. Although proof of concept has been shown for this approach with in vitro experiments, further research is needed to develop more potent inhibitors with low toxicity which is clinically effective.
Efflux as a mechanism of antimicrobial drug resistance in clinical relevant microorganisms: the role of efflux inhibitors
Creators: name: Willers, Clarissa
name: Wentzel, Johannes Frederik
name: Lissinda Hester Du Plessis
name: Chrisna Gouws
name: Josias Hendrik Hamman
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Introduction: Microbial resistance against antibiotics is a serious threat to the effective treatment of infectious diseases. Several mechanisms exist through which microorganisms can develop resistance against antimicrobial drugs, of which the over-expression of genes to produce efflux pumps is a major concern. Several efflux transporters have been identified in microorganisms, which infer resistance against specific antibiotics and even multi-drug resistance. Areas covered: This paper focuses on microbial resistance against antibiotics by means of the mechanism of efflux and gives a critical overview of studies conducted to overcome this problem by combining efflux pump inhibitors with antibiotics. Information was obtained from a literature search done with MEDLINE, Pubmed, Scopus, ScienceDirect, OneSearch and EBSCO host. Expert opinion: Efflux as a mechanism of multi-drug resistance has presented a platform for improved efficacy against resistant microorganisms by co-administration of efflux pump inhibitors with antimicrobial agents. Although proof of concept has been shown for this approach with in vitro experiments, further research is needed to develop more potent inhibitors with low toxicity which is clinically effective.
Data Table of Pınarbaşı Bird Remains Measurements [Structured Data from Open Context]
Creators: name: Nerissa Russell
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Data Table of Pınarbaşı Bird Remains Measurements Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 150-data-table-of-pinarbasi-bird-remains-measurements-1.csv contains the tabular data content for this resource in a CSV format.
JSON: The 150-data-table-of-pinarbasi-bird-remains-measurements-1.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
A new sulfonylated flavonoid and other bioactive compounds isolated from the aerial parts of Cotula anthemoides L.
Creators: name: Tadrent, Wafa
name: Abdulmagid Alabdul Magid
name: Kabouche, Ahmed
name: Harakat, Dominique
name: Voutquenne-Nazabadioko, Laurence
name: Kabouche, Zahia
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: A new sulfonyl flavonol glucoside, 5,7,4′,5′-tetrahydoxyflavonol 2′-[propanoic acid-(2″′-acetoxy-1″′-sulfonyl)]-5′-O-β-d-glucopyranoside (1) was isolated from the aerial parts of Cotula anthemoides L. in addition to 15 known compounds (2–16). The structure elucidation of these compounds was based on analyses of spectroscopic data including 1D-, 2D-NMR and HR-ESI-MS techniques and by comparing their NMR data with those reported in the literature. These compounds were evaluated for their DPPH radical scavenging and tyrosinase inhibitory activity. Compound 6 showed a high DPPH radical scavenging with EC50 value of 9.1 ± 0.4 μM. Compound 11, 9 and 1 exhibited a mild tyrosinase inhibitory activity with IC50 values of 85 ± 0.8, 95 ± 1.5 and 100 ± 0.5 μM, respectively.
[Querida Rosa : Esta semana no va nada mío]
Creators: name: Manuel, Vázquez Portal
name: Vázquez Portal, Manuel
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: Littérature
'Memorias de la Plaza'

description: Destinataire : Berre, Rosa
description: Description : Lettre de Vázquez Portal à son éditrice, Rosa Berre, directrice de Cubanet. L'auteur évoque: son état d'esprit, l'envoi de la troisième partie de son roman 'Memorias de la Plaza' et d'un cahier intitulé 'Performance', l'envoi de tous ses poèmes, la circulation d'un écrit ('Celda número cero'), son travail sur un ouvrage qui s'intitulera 'Segunda inocencia'.
description: Notes : La fin de la lettre est rédigée verticalement dans la marge gauche de la page.
description: Source: Cote : MVP-B-2003-03-18
description: Source: Localisation du document : États-Unis, Miami (Floride)
Mutation of the SP1 gene is responsible for the small-panicle trait in the rice cultivar Tachisuzuka, but not necessarily for high sugar content in the stem
Creators: name: Tatsuro Hirose
name: Kadoya, Sakurako
name: Hashida, Yoichi
name: Okamura, Masaki
name: Ohsugi, Ryu
name: Aoki, Naohiro
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Tachisuzuka, a rice cultivar grown for whole-crop silage, is characterized by the small-panicle trait and high-stem sugar content. To investigate the interrelationship between the two features, we attempted to identify the gene responsible for the small-panicle trait in Tachisuzuka, and also to examine the function of the gene using a knockout mutant line. A functionally disruptive deletion of the nucleotide sequence was found in the gene SP1 (Short-Panicle 1; Os11g0235200) in Tachisuzuka, which has been reported as a candidate gene for the small-panicle trait. A gene knockout mutant of SP1 obtained from the cultivar Nipponbare showed a small-panicle phenotype similar to that observed in Tachisuzuka. However, soluble sugar content in the stem did not increase in the knockout line, whereas starch content increased significantly. Overall, disruption of SP1 is responsible for the small-panicle phenotype of Tachisuzuka, but it is only partially associated with the high-stem sugar content.
Creating the medical school of the future through incremental curricular transformation: the Stanford Healthcare Innovations and Experiential Learning Directive (SHIELD)
Creators: name: Lin, Steven
name: Osborn, Kim
name: Sattler, Amelia
name: Nelligan, Ian
name: Svec, David
name: Aaronson, Alistair
name: Schillinger, Erika
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Creating the medical school of the future through incremental curricular transformation: the Stanford Healthcare Innovations and Experiential Learning Directive (SHIELD)
Dynamic Maintenance Scheduling with Fuzzy Data via Biogeography-based Optimization Algorithm and its Hybridizations
Creators: name: Pasura Aungkulanon
Publisher: name: King Mongkut's Institute of Technology Ladkrabang
Year: 2020
Subjects: dynamic maintenance, fuzzy data, metaheuristic, biogeography-based optimization, variable neighborhood search, particle swarm optimization

description: Current Applied Science and Technology, 20, 2, 226-237
Insight into the adsorption mechanisms of trace organic carbon on biological treatment process
Creators: name: Zolfaghari, Mehdi
name: Drogui, Patrick
name: Brar, Satinder Kaur
name: Buelna, Gerardo
name: Dubé, Rino
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: The presence of recalcitrant dissolved organic matter (DOM) could have a significant effect on the adsorption mechanism and capacity of the sludge for many trace organic carbons (TrOCs). In this study, adsorption of three TrOCs on the sludge and HA was investigated. The results revealed that neutral hydrophilic compounds had an insignificant interaction with both sludge and HA. Positively charged compounds, such as fluoranthene, had more affinity toward HA than sludge with solid/liquid partitioning of 57 and 3.2 L/g, respectively. The adsorption intensity (Kf) of di-2-ethyl hexyl phthalate was 0.5 and 1.13 for the HA and the sludge, respectively. By introducing the sludge to the solution of HA and TrOCs that already reached equilibrium, the sludge adsorption capacity in the presence of HA was investigated. The finding showed that at the lower concentration, adsorption of HA on the sludge was considered as the main removal pathway for the adsorbed emerging contaminants, as 70 mg of HA was adsorbed by a gram of sludge. For the higher concentration, desorption of TrOCs from DOM into the sludge comprised 15–30% of total removal efficiency. Abbreviations: CBZ: carbamazepine; DEHP: di-2-ethyl hexyl phthalate; DOM: dissolved organic matter; FLAN: fluoranthene; foc: fraction of organic carbon; HA: humic acid; Log Kow: octanol–water partition coefficient; PAH: polycyclic aromatic hydrocarbon TS: total solid; TrOCs: trace organic carbons VS: volatile solid
Data Table of Naga ed-Deir, Cemeteries N 2000 and N 2500 Objects [Structured Data from Open Context]
Creators: name: Vanessa Davies
name: Gabriella diBattista
name: Elizabeth Minor
name: Virginia L. Emery
name: Emily Teeter
name: Lisa Maher
name: N/A
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Data Table of Naga ed-Deir, Cemeteries N 2000 and N 2500 Objects Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 149-data-table-of-naga-ed-deir-cemeteries-n-2000-and-n-250.csv contains the tabular data content for this resource in a CSV format.
JSON: The 149-data-table-of-naga-ed-deir-cemeteries-n-2000-and-n-250.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
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title: Fertilization and Mouse Embryo Development in the Presence of Midazolam
Creators: name: Leavitt, Maria
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1991

description: The development of mouse embryos in vitro has provided a unique opportunity for the study of cellular differentiation and the influence of various agents on differentiation. Midazolam is administered for conscious sedation in the recovery of human ova. In the Norfolk IVF Program, midazolam is found in varying concentrations in follicular fluid. Mouse embryo formation and development has been used to test midazolam's effect on fertilization and early development as a model of human in vitro fertilization and development. Midazolam' s effects were studied using varying doses of midazolam on (1) in vivo fertilization and subsequent cell division, and (2) co-culture with 2-cell mouse embryos during development to blastocyst stage. Midazolam has no effect on in vivo fertilization and subsequent cell division nor on in vitro development of 2-cell mouse embryos when present in concentrations calculated to approximate and exceed those to which human ova would be exposed during clinical anesthesia. Results indicate that recommended doses of midazolam given during the harvesting of human ova have no inhibitory effect on in vitro fertilization and consequent embryo development.
title: Flood Control Dike Improvements (NWS-2021-460, WDFW)
titleType: AlternativeTitle
title: "Endangered Species Act Section 7 Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Response for the Wiley Slough Levee and Tidegate Repair, Skagit County, Washington."
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2022

description: ESA Section 7 Consultation ; WCRO-2021-03107
The conformational feasibility for the formation of reaching dimer in ASV and HIV integrase: a molecular dynamics study
Creators: name: Sangeetha Balasubramanian
name: Muthukumaran Rajagopalan
name: Bojja, Ravi Shankar
name: Skalka, Anna Marie
name: Andrake, Mark D.
name: Amutha Ramaswamy
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Retroviral integrases are reported to form alternate dimer assemblies like the core–core dimer and reaching dimer. The core–core dimer is stabilized predominantly by an extensive interface between two catalytic core domains. The reaching dimer is stabilized by N-terminal domains that reach to form intermolecular interfaces with the other subunit’s core and C-terminal domains (CTD), as well as CTD–CTD interactions. In this study, molecular dynamics (MD), Brownian dynamics (BD) simulations, and free energy analyses, were performed to elucidate determinants for the stability of the reaching dimer forms of full-length Avian Sarcoma Virus (ASV) and Human Immunodeficiency Virus (HIV) IN, and to examine the role of the C-tails (the last ~16–18 residues at the C-termini) in their structural dynamics. The dynamics of an HIV reaching dimer derived from small angle X-ray scattering and protein crosslinking data, was compared with the dynamics of a core–core dimer model derived from combining the crystal structures of two-domain fragments. The results showed that the core domains in the ASV reaching dimer express free dynamics, whereas those in the HIV reaching dimer are highly stable. BD simulations suggest a higher rate of association for the HIV core–core dimer than the reaching dimer. The predicted stability of these dimers was therefore ranked in the following order: ASV reaching dimer
Damasus et Laurentius Hispanis assérti et vindicati, dissertatio historica, auctore Francisco Perazio Bayerio...
Creators: name: Perez Bayer, Francesco
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: Bibliothèque patrimoniale Villon (Rouen), fonds Liber, Mt g 399