cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Direct evidence for W exchange in charmed meson decay
Creators: name: Albrecht, H.
name: Binder, U.
name: Harder, G.
name: Philipp, A.
name: Schmidt-Parzefall, W.
name: Schröder, H.
name: Schulz, H. D.
name: Wurth, R.
name: Drescher, A.
name: Gräwe, B.
name: Matthiesen, U.
name: Scheck, H.
name: Spengler, J.
name: Wegener, D.
name: Schubert, K. R.
name: Stiewe, J.
name: Waldi, R.
name: Weseler, S.
name: Brown, N. N.
name: Edwards, K. W.
name: Frisken, W. R.
name: Fukunaga, Ch.
name: Gilkinson, D. J.
name: Gingrich, D. M.
name: Goddard, M.
name: Kim, P. C. H.
name: Kutschke, R.
name: Macfarlane, D. B.
name: McKenna, J. A.
name: McLean, K. W.
name: Nilsson, A. W.
name: Orr, R. S.
name: Padley, P.
name: Patel, P. M.
name: Prentice, J. D.
name: Seywerd, H. C. J.
name: Stacey, B. J.
name: Yoon, T.-S.
name: Yun, J. C.
name: Ammar, R.
name: Coppage, D.
name: Davis, R.
name: Kanekal, S.
name: Kwak, N.
name: Kernel, G.
name: Pleško, M.
name: Jönsson, L.
name: Oku, Y.
name: Babaev, A.
name: Danilov, M.
name: Golutvin, A.
name: Lubimov, V.
name: Matveev, V.
name: Nagovitsin, V.
name: Ryltsov, V.
name: Semenov, A.
name: Shevchenko, V.
name: Soloshenko, V.
name: Sopov, V.
name: Tichomirov, I.
name: Zaitsev, Yu.
name: Childers, R.
name: Darden, C. W.
name: Gennow, H.
name: ARGUS Collaboration
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 1985
Subjects: subject: 530
subject: ELECTRON POSITRON: COLLIDING BEAMS
subject: COLLIDING BEAMS: ELECTRON POSITRON
subject: ELECTRON POSITRON: INCLUSIVE REACTION
subject: D0: ELECTROPRODUCTION
subject: ELECTROPRODUCTION: D0
subject: D0: NONLEPTONIC DECAY
subject: NONLEPTONIC DECAY: D0
subject: W: EXCHANGE
subject: EXCHANGE: W
subject: FINAL STATE: (PHI(1020) K0(S))
subject: (PHI(1020) K0(S)): FINAL STATE
subject: D0: BRANCHING RATIO
subject: ARGUS
subject: EXPERIMENTAL RESULTS
subject: DESY DORIS II STOR
subject: D0 --> PHI(1020) K0(S)
subject: 9.4-10.6 GEV-CMS
subject: S032.3
subject: S032.31

description: Using the ARGUS detector at DORIS II, we have observed a signal of 36.7±8.0 events in the decay channel D 0 →K s 0 φ . In the same data sample, we have observed the well established decay D 0 →K s 0 π + π − , and find the ratio, Br(D) 0 → K s 0 φ) Br(D) 0 → K s 0 π + π − ) , to be 0.186±0.052. The substantial value of (0.99±0.32±0.17)% then derived for the branching ratio for D 0 → K 0 φ gives direct evidence that W exchange contributes D 0 decay.
How Bad/Good Are the External Forward Shock Afterglow Models of Gamma-Ray Bursts?
Creators: name: Wang, Xiang-Gao
name: Zhang, Bing
name: Liang, En-Wei
name: Gao, He
name: Li, Liang
name: Deng, Can-Min
name: Qin, Song-Mei
name: Tang, Qing-Wen
name: Kann, D. Alexander
name: Ryde, Felix
name: Kumar, Pawan
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The external forward shock (EFS) models have been the standard paradigm to interpret the broad-band afterglow data of gamma-ray bursts (GRBs). One prediction of the models is that some afterglow temporal breaks at different energy bands should be achromatic. Observations in the Swift era have revealed chromatic afterglow behaviors at least in some GRBs, casting doubts on the EFS origin of GRB afterglows. In this paper, we perform a systematic study to address the question: how bad/good are the external forward shock models? Our sample includes 85 GRBs well-monitored X-ray and optical lightcurves. Based on how well the data abide by the EFS models, we categorize them as: Gold sample: (Grade I and II) include 45/85 GRBs. They show evidence of, or are consistent with having, an achromatic break. The temporal/spectral behaviors in each afterglow segment are consistent with the predictions (closure relations) of the EFS models. Silver sample: (Grade III and IV) include 37/85 GRBs. They are also consistent with having an achromatic break, even though one or more afterglow segments do not comply with the closure relations. Bad sample: (Grade V), 3/85 shows direct evidence of chromatic behaviors, suggesting that the EFS models are inconsistent with the data. These are included in the Bad sample. We further perform statistical analyses of various observational properties ($α$, $β$, $t_b$ and model parameters (energy injection index q, p, $θ_j$, $η_γ$, etc) of the GRBs in the Gold Sample, and derive constraints on the magnetization parameter $ε_B$ in the EFS. Overall, we conclude that the simplest EFS models can account for the multi-wavelength afterglow data of at least half of the GRBs. When more advanced modeling (e.g., long-lasting reverse shock, structured jets) is invoked, up to $>90 \%$ of the afterglows may be interpreted within the framework of the ESF models.
description: 69 pages,134 figures, 7 tables, ApJS, in press
Repressing gene transcription by redirecting cellular machinery with chemical epigenetic modifiers
Creators: name: Hathaway, N.A.
name: Butler, K.V.
name: Wang, T.A.
name: Jin, J.
name: Chiarella, A.M.
Publisher: name: Journal of Visualized Experiments
Year: 2018

description: Regulation of chromatin compaction is an important process that governs gene expression in higher eukaryotes. Although chromatin compaction and gene expression regulation are commonly disrupted in many diseases, a locus-specific, endogenous, and reversible method to study and control these mechanisms of action has been lacking. To address this issue, we have developed and characterized novel gene-regulating bifunctional molecules. One component of the bifunctional molecule binds to a DNA-protein anchor so that it will be recruited to an allele-specific locus. The other component engages endogenous cellular chromatin-modifying machinery, recruiting these proteins to a gene of interest. These small molecules, called chemical epigenetic modifiers (CEMs), are capable of controlling gene expression and the chromatin environment in a dose-dependent and reversible manner. Here, we detail a CEM approach and its application to decrease gene expression and histone tail acetylation at a Green Fluorescent Protein (GFP) reporter located at the Oct4 locus in mouse embryonic stem cells (mESCs). We characterize the lead CEM (CEM23) using fluorescent microscopy, flow cytometry, and chromatin immunoprecipitation (ChIP), followed by a quantitative polymerase chain reaction (qPCR). While the power of this system is demonstrated at the Oct4 locus, conceptually, the CEM technology is modular and can be applied in other cell types and at other genomic loci.
Classical models of confinement with moving charges
Creators: name: Lehmann, Harry
name: Wu, Tai Tsun
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 1986
Subjects: subject: 530
subject: QUARK: CONFINEMENT
subject: CLASSICAL
subject: Maxwell equation
subject: POTENTIAL

description: We investigate a class of abelian models which lead to a linear potential between opposite charges. For uniformly moving charges with opposite velocities, the electromagnetic fields and the confining domains are obtained asymptotically for large separations.
Cavitation Enhancement Increases the Efficiency and Consistency of Chromatin Fragmentation from Fixed Cells for Downstream Quantitative Applications
Creators: name: Hathaway, N.A.
name: Kasoji, S.K.
name: Dayton, P.A.
name: Quimby, A.L.
name: Mehrab-Mohseni, M.
name: Pattenden, S.G.
name: Davis, I.J.
name: Chiarella, A.M.
name: Velasco, B.
Publisher: name: American Chemical Society
Year: 2018

description: One of the most sensitive, time-consuming, and variable steps of chromatin immunoprecipitation (ChIP) is chromatin sonication. Traditionally, this process can take hours to properly sonicate enough chromatin for multiple ChIP assays. Further, the length of sheared DNA is often inconsistent. In order to faithfully measure chemical and structural changes at the chromatin level, sonication needs to be reliable. Thus, chromatin fragmentation by sonication represents a significant bottleneck to downstream quantitative analysis. To improve the consistency and efficiency of chromatin sonication, we developed and tested a cavitation enhancing reagent based on sonically active nanodroplets. Here, we show that nanodroplets increase sonication efficiency by 16-fold and provide more consistent levels of chromatin fragmentation. Using the previously characterized chromatin in vivo assay (CiA) platform, we generated two distinct chromatin states in order to test nanodroplet-assisted sonication sensitivity in measuring post-translational chromatin marks. By comparing euchromatin to chemically induced heterochromatin at the same CiA:Oct4 locus, we quantitatively measure the capability of our new sonication technique to resolve differences in chromatin structure. We confirm that nanodroplet-assisted sonication results are indistinguishable from those of samples processed with traditional sonication in downstream applications. While the processing time for each sample was reduced from 38.4 to 2.3 min, DNA fragment distribution sizes were significantly more consistent with a coefficient of variation 2.7 times lower for samples sonicated in the presence of nanodroplets. In conclusion, sonication utilizing the nanodroplet cavitation enhancement reagent drastically reduces the amount of processing time and provides consistently fragmented chromatin of high quality for downstream applications.
Biblioteconomia no contexto da E-Science: a formação do(a) bibliotecário(a) de dados em instituições de ensino superior brasileiras
Creators: name: Garrido, Fabrício Rodrigues dos Santos
name: Martins, Gracy Kelli
Publisher: name: Zenodo
Year: 2022

description: Apresentação realizada na sessão O meu Póster em 40 segundos da 13ª Conferência Lusófona de Ciência Aberta, formato híbrido, de 10 a 12 de outubro de 2022.
Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes
Creators: name: Crabtree, G.R.
name: Muegge, K.
name: Hathaway, N.A.
name: Ren, J.
Publisher: name: Taylor and Francis Inc.
Year: 2018

description: Lsh is a chromatin remodeling factor that regulates DNA methylation and chromatin function in mammals. The dynamics of these chromatin changes and whether they are directly controlled by Lsh remain unclear. To understand the molecular mechanisms of Lsh chromatin controlled regulation of gene expression, we established a tethering system that recruits a Gal4-Lsh fusion protein to an engineered Oct4 locus through Gal4 binding sites in murine embryonic stem (ES) cells. We examined the molecular epigenetic events induced by Lsh binding including: histone modification, DNA methylation and chromatin accessibility to determine nucleosome occupancy before and after embryonic stem cell differentiation. Our results indicate that Lsh assists gene repression upon binding to the Oct4 promoter region. Furthermore, we detected less chromatin accessibility and reduced active histone modifications at the tethered site in undifferentiated ES, while GFP reporter gene expression and DNA methylation patterns remained unchanged at this stage. Upon differentiation, association of Lsh promotes transcriptional repression of the reporter gene accompanied by the increase of repressive histone marks and a gain of DNA methylation at distal and proximal Oct4 enhancer sites. Taken together, this approach allowed us to examine Lsh mediated epigenetic regulation as a dynamic process and revealed chromatin accessibility changes as the primary consequence of Lsh function.
title: Slip tendency analysis for 60 3D faults in Germany and adjacent areas
Creators: name:  Röckel , Luisa
name:  Ahlers , Steffen
name:  Müller , Birgit
name:  Reiter , Karsten
name:  Heidbach , Oliver
name:  Hergert , Tobias
name:  Henk , Andreas
name:  Schilling , Frank
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Tectonic faults are of great importance for many underground applications such as hydrocarbon extraction, geothermal operations or nuclear waste repositories. In particular, the fault reactivation potential is crucial in regards of safety and efficiency of these applications. Major influences on the reactivation potential are the contemporary tectonic stress field and changes to it due to anthropogenic activities. One measure of the reactivation potential of faults is the ratio of resolved shear stresses to normal stresses on the fault surface, the slip tendency. The components of the stress tensor required for slip tendency analysis have been provided by the 3D geomechanical numerical model of Germany and its adjacent regions of the SpannEnD project. The derived stresses are mapped onto selected faults in order to calculate their slip tendency. As only a finite number of 3D fault geometries could be generated, criteria for the selection of faults relevant to the scope of the SpannEnD project were identified. Their application led to the selection of 60 faults in the model area. For the selected faults simplified geometries were created (fault set 1). For a subset of the selected faults, vertical profiles and seismic sections could be used to generate semi-realistic 3D fault geometries (fault set 2). Slip tendency calculations using the stress tensor from the SpannEnD model were performed for both 3D fault sets and allow for an assessment of the fault reactivation potential which can be compared with the distribution of seismicity.
Targeted Gene Repression Using Novel Bifunctional Molecules to Harness Endogenous Histone Deacetylation Activity
Creators: name: Jin, J.
name: Chiarella, A.M.
name: Hathaway, N.A.
name: Butler, K.V.
Publisher: name: American Chemical Society
Year: 2018

description: Epigenome editing is a powerful method for life science research and could give rise to new therapies for diseases initiated or maintained by epigenetic dysregulation, including several types of cancers and autoimmune disorders. In addition, much is still unknown about the mechanisms by which histone-modifying proteins work in concert to properly regulate gene expression. To investigate and manipulate complex epigenetic interactions in live cells, we have developed a small molecule platform for specifically inducing gene repression and histone deacetylation at a reporter gene. We synthesized bifunctional ligands, or chemical epigenetic modifiers (CEMs), that contain two functional groups: a FK506 derivative capable of binding to a FKBP-Gal4 fusion transcription factor, and a histone deacetylase (HDAC) inhibitor that recruits HDAC-containing corepressor complexes. In our reporter cell line, which contains a GFP reporter allele upstream of a Gal4 DNA binding array in the murine Oct4 locus, our lead CEM repressed GFP expression by 50%. We also show that CEM recruitment of deacetylation activity causes marked deacetylation along our target loci. This system allowed us to detail the direct results of deacetylation to chromatin and measure the resulting gene expression in a chemically dependent and reversible manner. The CEMs system provides new insights into epigenetic gene regulation and has the potential to control disease-relevant gene regulation. The CEMs are derived from FDA-approved epigenetic modulator drugs, and use their pharmacology in a gene-specific way that avoids the toxicities and off-target effects caused by whole-cell application of these drugs.
Report and Application of a Tool Compound Data Set
Creators: name: Butler, K.V.
name: Macdonald, I.A.
name: Hathaway, N.A.
name: Jin, J.
Publisher: name: American Chemical Society
Year: 2017

description: Small molecule tool compounds have enabled profound advances in life science research. These chemicals are potent, cell active, and selective, and, thus, are suitable for interrogating biological processes. For these chemicals to be useful they must be correctly characterized and researchers must be aware of them. We mined the ChEMBL bioactivity database to identify high quality tool compounds in an unbiased way. We identified 407 best-in-class compounds for 278 protein targets, and these are reported in an annotated data set. Additionally, we developed informatics functions and a web application for data visualization and automated pharmacological hypothesis generation. These functions were used to predict inhibitors of the Chromobox Protein Homologue 5 (CBX5) mediated gene repression pathway that currently lacks appropriate inhibitors. The predictions were subsequently validated by a highly specific cell based assay, revealing new chemical modulators of CBX5-mediated heterochromatin formation. This data set and associated functions will help researchers make the best use of these valuable compounds.
Atividade e experiência da comissão de ética numa instituição de ensino superior
Creators: name: Rodrigues, Maria Eduarda Pereira
name: Lourenço, Isabel Maria de Sousa
Publisher: name: Zenodo
Year: 2022

description: Apresentação realizada na sessão O meu Póster em 40 segundos da 13ª Conferência Lusófona de Ciência Aberta, formato híbrido, de 10 a 12 de outubro de 2022.
Quartierspiegel Schwamendingen-Mitte 2020
Creators: name: (:Unkn) Unknown
Publisher: name: Zentralbibliothek Zürich
Year: 2020
Subjects: subject: 314 Allgemeine Statistiken zu Europa
subject: 710 Städtebau, Raumplanung, Landschaftsgestaltung
subject: 949 Geschichte anderer Teile Europas
subject: Zürich-Schwamendingen
subject: Quartier
subject: Amtliche Statistik
subject: Bevölkerungsstatistik

description: Die in dieser Ausgabe publizierten Daten beziehen sich zum grössten Teil auf folgenden Zeitabschnitt : 2019
description: Bis in die 1940er-Jahre war Schwamendingen ein Bauerndorf, wovon noch heute die historischen Bauten am Schwamendingerplatz zeugen, dem Zentrum des Quartiers Schwamendingen-Mitte: Hier findet nicht nur der allwöchentliche «Schwamendinger Märt» statt, sondern auch das Frühlingsfest MOSAIK oder die «Schwamendinger Chilbi».
A heuristic rule for classification of classical fluids: Master curves for Mie, Yukawa and square-well potentials
Creators: name: Orea, Pedro
name: Varga, Szabolcs
name: Odriozola, Gerardo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: A shift of the vapor-liquid coexistence curves by the critical value of the reduced second virial coefficient yields striking data collapses to define master curves. This is observed for the Mie, Yukawa and square-well fluids of different attractive ranges. This modification of the extended corresponding-states law of Noro and Frenkel strongly improves the outcomes from the van der Waals principle. Moreover, this shifted extended principle makes the master curves from Mie and Yukawa potentials to be one on top of the other. The square-well potential forms two well defined master curves, each one corresponding to different effective critical exponents.
description: 10 pages, 2 figures
Influence of Facebook in Academic Performance of Sri Lankan University Students
Creators: name: Thuseethan, S.
name: Kuhanesan, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Facebook is only an electronic communication between human but unfortunately it has become an addiction for all. This paper examines the usage of Facebook among university students and its influence in their academic performance. The impact of Facebook can either be good or bad on university students and in their academic activities. Even though a closer look on the real impact of Facebook reveals that it leads to several problems in university students academic performances. Today Facebook is somehow destroying the future and academic carrier of university students. At the same time also intended to find the significance of use of Facebook by University students in their academic success with the help of a survey conducted to collect the data among more than 250 students of different Universities in Sri Lanka.
Embedding open and participatory research into research training
Creators: name: Hsing, Pen-Yuan
Publisher: name: Zenodo
Year: 2023
Subjects: open science
open research
open educational resources
citizen science
Wikipedia

description: Creativity is built on top of existing knowledge. In other words, "everything is a remix". This talk will use examples from research and teaching to demonstrate the critical role of sharing knowledge, specifically a citizen science project for ecological monitoring and Wikipedia-editing assignments in undergraduate education.
A First Detection of the Acoustic Oscillation Phase Shift Expected from the Cosmic Neutrino Background
Creators: name: Follin, Brent
name: Knox, Lloyd
name: Millea, Marius
name: Pan, Zhen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The unimpeded relativistic propagation of cosmological neutrinos prior to recombination of the baryon-photon plasma alters gravitational potentials and therefore the details of the time-dependent gravitational driving of acoustic oscillations. We report here a first detection of the resulting shifts in the temporal phase of the oscillations, which we infer from their signature in the Cosmic Microwave Background (CMB) temperature power spectrum.
description: 5 pages, 3 figures
title: Hacking the street - regenerative design principles for the existing urban street section and public realm
Creators: name: Haase, Marie H
Publisher: name: University of Southampton
Year: 2022
Subjects: regenerative design, urban microclimate, pedestrian comfort, flood resilience, bioremediation

description: According to the UN, two out of every three people on the planet will live in cities by 2050 (UN-DESA, 2019). For sustainable development, cities must dynamically control and restrict their growth, save biodiversity and ecosystems, and at the same time address housing needs. Cities must simultaneously lessen their influence on the microclimate and increase their resistance to climate change. Brownfield site infill and urban regeneration, which revitalise the neighbourhood and environment, are one solution.
The design project incorporates regenerative techniques and natural components into the existing street section of Wallis Road in London, UK, a former industrial site, based on environmental studies, working with the terrain through measures of soil bioremediation and flood resilience.
The developed prototype is a sustainable addition that adapts to the local environment and enhances the microclimate of the neighbourhood, pedestrian comfort, and ecological regeneration while reducing the effects of climate change on the urban population.
Short Term Effects of Virtual Reality Based Exergaming on Clinical Outcomes and Brain Morphometry in Patients with Parkinson's Disease
Creators: name: Hajebrahimi, Farzin
name: Velioglu, Halil Aziz
name: Helvaci Yilmaz, Nesrin
name: Bayraktaroglu, Zubeyir
name: Lutfu Hanoglu
Publisher: name: Zenodo
Year: 2020
Subjects: Morphometry
Volumetric Analysis
Virtual Reality
Parkinson's Disease
Neuroplasticity

description: This poster will be presented in the FENS virtual forum 2020.
Magnetic activity and its variability in the Sun and solar-like stars
Creators: name: Santos, Ângela R. G.
name: Mathur, Savita
name: García, Rafael A.
name: Broomhall, Anne-Marie
name: Egeland, Ricky
name: Jiménez, Antonio
name: Godoy-Rivera, Diego
name: Breton, Sylvain N.
name: Claytor, Zachary R.
name: Metcalfe, Travis S.
name: Cunha, Margarida S.
name: Amard, Louis
Publisher: name: Zenodo
Year: 2024

description: The light curves of solar-like stars provide information on stellar rotation and magnetic activity thanks to active-region crossings. In this work, we investigate the temporal variation of the photometric magnetic activity of the Sun and Kepler solar-like stars. We find that the most active stars are those exhibiting the most significant variations, independently of the spectral type. This relationship was known for chromospheric activity, but here we show that photometric data have a similar behavior. Because of the bimodal rotation-period distribution, there are two regimes in the activity-rotation relation: slow- and fast-rotating branches. While stars in the fast-rotating branch tend to have higher activity levels (in general) than the slow-rotating branch, their temporal variation is consistent, with both branches following the same relationship. We also compare the Sun with Sun-like stars, a subsample with very similar properties to the Sun selected according to effective temperature, surface gravity, and rotation. While the Sun is among the less active stars (depending on the cycle’s phase), we find that the behavior of the Sun’s magnetic activity is consistent with that of Kepler Sun-like stars. Finally, we also find evidence for the metallicity impact on the rotation evolution. This kind of analysis helps improve our understanding of solar/stellar magnetism and its associated timescales. Future PLATO data will bring a new opportunity in this direction.
A Method to Calculate Conserved Currents and Fermionic Force for the Lanczos Approximation to the Overlap Dirac Operator
Creators: name: Puhr, M.
name: Buividovich, P. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The overlap Dirac operator obeys the Ginsparg-Wilson equation and offers a possibility to introduce chiral symmetry on the lattice. Evaluating the overlap operator is numerically very expensive and one has to rely on approximation methods. At finite chemical potential the overlap operator can be efficiently computed with the two-sided Lanczos algorithm. To calculate conserved currents on the lattice, or to evaluate the fermionic force in HMC calculations, one needs to compute derivatives of the Dirac operator with respect to gauge fields. In this paper we present a method to simultaneously compute the action of the overlap operator and its derivative on a source vector.
description: 7 pages PoS style, 1 figure, to appear in the proceedings of the Lattice 2014 conference (23-28 June 2014, Columbia University, New York, USA)
title: Compressive Sensing Based Grant-Free Communication
Creators: name: Wang, Yuanchen
Publisher: name: University of Liverpool Repository
Year: 2022

description: Grant-free communication, where each user can transmit data without following the strict access grant process, is a promising technique to reduce latency and support massive users. In this thesis, compressive sensing (CS), which exploits signal sparsity to recover data from a small sample, is investigated for user activity detection (UAD), channel estimation, and signal detection in grant-free communication, in order to extract information from the signals received by base station (BS). First, CS aided UAD is investigated by utilizing the property of quasi-time-invariant channel tap delays as the prior information for the burst users in internet of things (IoT). Two UAD algorithms are proposed, which are referred to as gradient based and time-invariant channel tap delays assisted CS (g-TIDCS) and mean value based and TIDCS (m-TIDCS), respectively. In particular, g-TIDCS and m-TIDCS do not require any prior knowledge of the number of active users like the existing approaches and therefore are more practical. Second, periodic communication as one of the salient features of IoT is considered. Two schemes, namely periodic block orthogonal matching pursuit (PBOMP) and periodic block sparse Bayesian learning (PBSBL), are proposed to exploit the non-continuous temporal correlation of the received signal for joint UAD, channel estimation, and signal detection. The theoretical analysis and simulation results show that the PBOMP and PBSBL outperform the existing schemes in terms of the success rate of UAD, bit error rate (BER), and accuracy in period estimation and channel estimation. Third, UAD and channel estimation for grant-free communication in the presence of massive users that are actively connected to the BS is studied. An iteratively UAD and signal detection approach for the burst users is proposed, where the interference of the connected users on the burst users is reduced by applying a preconditioning matrix to the received signals at the BS. The proposed approach is capable of providing significant performance gains over the existing algorithms in terms of the success of UAD and BER. Last but not least, since the physical layer security becomes a critical issue for grant-free communication, the channel reciprocity in time-division duplex systems is utilized to design environment-aware (EA) pilots derived from transmission channels to prevent eavesdroppers from acquiring users’ channel information. The proposed EA-pilots based approach possesses a high level of security by scrambling the eavesdropper’s normalized mean square error performance of channel estimation.
Dynamics and memory of heterochromatin in living cells
Creators: name: Neel, D.S.
name: Hodges, C.
name: Hathaway, N.A.
name: Bell, O.
name: Miller, E.L.
name: Crabtree, G.R.
Publisher: name: Elsevier B.V.
Year: 2012

description: Posttranslational histone modifications are important for gene regulation, yet the mode of propagation and the contribution to heritable gene expression states remains controversial. To address these questions, we developed a chromatin in vivo assay (CiA) system employing chemically induced proximity to initiate and terminate chromatin modifications in living cells. We selectively recruited HP1α to induce H3K9me3-dependent gene silencing and describe the kinetics and extent of chromatin modifications at the Oct4 locus in fibroblasts and pluripotent cells. H3K9me3 propagated symmetrically and continuously at average rates of ∼0.18 nucleosomes/hr to produce domains of up to 10 kb. After removal of the HP1α stimulus, heterochromatic domains were heritably transmitted, undiminished through multiple cell generations. Our data enabled quantitative modeling of reaction kinetics, which revealed that dynamic competition between histone marking and turnover, determines the boundaries and stability of H3K9me3 domains. This framework predicts the steady-state dynamics and spatial features of the majority of euchromatic H3K9me3 domains over the genome.
Interacting holographic dark energy models: A general approach
Creators: name: Som, S.
name: Sil, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Dark energy models inspired by the cosmological holographic principle are studied in homogeneous isotropic spacetime with a general choice for the dark energy density $ρ_d=3(αH^2+β\dot{H})$. Special choices of the parameters enable us to obtain three different holographic models, including the holographic Ricci dark energy(RDE) model. Effect of interaction between dark matter and dark energy on the dynamics of those models are investigated for different popular forms of interaction. It is found that crossing of phantom divide can be avoided in RDE models for $β>0.5$ irrespective of the presence of interaction. A choice of $α=1$ and $β=2/3$ leads to a varying $Λ$-like model introducing an IR cutoff length $Λ^{-1/2}$. It is concluded that among the popular choices an interaction of the form $Q\propto Hρ_m$ suits the best in avoiding the coincidence problem in this model.
description: 20 pages, 5 figures
Atividade legislativa em tempo de pandemia (COVID-19) - benefícios do Acesso Aberto
Creators: name: Rodrigues, Maria Eduarda Pereira
name: Peças, Isabel Assis Fonseca
Publisher: name: Zenodo
Year: 2022

description: Apresentação realizada na sessão O meu Póster em 40 segundos da 13ª Conferência Lusófona de Ciência Aberta, formato híbrido, de 10 a 12 de outubro de 2022.
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
Creators: name: King, R.W.
name: Gygi, S.P.
name: Hathaway, N.A.
name: Kirkpatrick, D.S.
name: Lee, B.-H
name: Dimova, N.V.
name: Finley, D.
name: Berkowitz, M.L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The anaphase-promoting complex or cyclosome (APC/C) initiates mitotic exit by ubiquitylating cell-cycle regulators such as cyclin B1 and securin. Lys 48-linked ubiquitin chains represent the canonical signal targeting proteins for degradation by the proteasome, but they are not required for the degradation of cyclin B1. Lys 11-linked ubiquitin chains have been implicated in degradation of APC/C substrates, but the Lys 11-chain-forming E2 UBE2S is not essential for mitotic exit, raising questions about the nature of the ubiquitin signal that targets APC/C substrates for degradation. Here we demonstrate that multiple monoubiquitylation of cyclin B1, catalysed by UBCH10 or UBC4/5, is sufficient to target cyclin B1 for destruction by the proteasome. When the number of ubiquitylatable lysines in cyclin B1 is restricted, Lys 11-linked ubiquitin polymers elaborated by UBE2S become increasingly important. We therefore explain how a substrate that contains multiple ubiquitin acceptor sites confers flexibility in the requirement for particular E2 enzymes in modulating the rate of ubiquitin-dependent proteolysis.
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
Creators: name: Hathaway, N.
name: Gaur, S.
name: Oh, D.-C.
name: King, R.W.
name: Dimova, N.
name: Choi, S.
name: Zeng, X.
name: Sigoillot, F.
name: Pfaff, K.L.
name: Cuny, G.D.
Publisher: name: Cell Press
Year: 2010

description: Microtubule inhibitors are important cancer drugs that induce mitotic arrest by activating the spindle assembly checkpoint (SAC), which, in turn, inhibits the ubiquitin ligase activity of the anaphase-promoting complex (APC). Here, we report a small molecule, tosyl-L-arginine methyl ester (TAME), which binds to the APC and prevents its activation by Cdc20 and Cdh1. A prodrug of TAME arrests cells in metaphase without perturbing the spindle, but nonetheless the arrest is dependent on the SAC. Metaphase arrest induced by a proteasome inhibitor is also SAC dependent, suggesting that APC-dependent proteolysis is required to inactivate the SAC. We propose that mutual antagonism between the APC and the SAC yields a positive feedback loop that amplifies the ability of TAME to induce mitotic arrest.
Generating realistic data for developing artificial neural network based SOC estimators for electric vehicles
Creators: name: Kalk, Alexis
name: Birkholz, Oleg
name: Zhang, Jiaming
name: Kupper, Christian
name: Hiller, Marc
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2023
Subjects: State of Charge
Artificial Neural Networks
Realistic Driving Cycle
SOC Estimation
Lithium-Ion Battery

description: Tracking the state of a lithium-ion battery in an electric vehicle (EV) is a challenging task. In order to tackle one aspect of this task, we choose a data-driven approach for estimating the State of Charge (SOC), which is one of the most import parameters. In this context, the quality of the provided data is of utmost importance. Usually, standardized driving profiles are used to generate current profiles which are then applied to battery cells during testing. However, these standardized driving profiles exhibit significant deviation from real-world conditions, which can considerably affect the learning and validation performance of data-driven approaches. In this paper, we first propose a test profile generator which generates realistic current profiles for EV battery testing. Second, to demonstrate the effect of the proposed test profiles a multilayer perceptron (MLP) based SOC estimator is presented. Finally, we compare the results to the standardized driving profiles.
Cannibalism, warfare, and drought in the Mesa Verde region during the twelfth century A.D.
Creators: name: Leonard B.L.
name: Lambert P.M.
name: Billman B.R.
Publisher: name: Society for American Archaeology
Year: 2000

description: The existence of cannibalism has emerged as one of the most controversial issues in the archaeology of the American Southwest. In this paper, we examine this issue by presenting the results of our investigation at 5MT10010, a small early Pueblo III habitation site in southwestern Colorado. Battered, broken bones from seven individuals were discovered in two adjacent pithouses at 5MT10010. Mixed and incomplete remains of four adults and an adolescent were recovered from the floor and ventilator shaft of one pithouse; the remains of two subadults were found on the floor and in various subfeatures of the second. Cut marks and percussion scars implicate humans in the disarticulation and reduction of these bodies. Evidence of heat exposure on some bone fragments and laboratory analyses of a human coprolite recovered from one of the pithouses support the interpretation that people prepared and consumed human body parts. The discovery of disarticulated human remains at 5MT10010 is one of a number of similar finds in the northern Southwest. Analysis of cases from the Mesa Verde region indicates a sharp increase in cannibalism around A.D. 1150, a time of drought and the collapse of the Chaco system. The causes, consequences, and nature of this apparent outbreak of cannibalism are examined in light of 5MT10010 and other recent finds.
Theory of spin polarization in mesoscopic spin-orbit coupling systems
Creators: name: Liang, Shi-Dong
name: Huang, Guang-Yao
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We establish a general formalism of the bulk spin polarization (BSP) and the current-based spin polarization (CSP) for mesoscopic ferromagnetic and spin-orbit interaction (SOI) semiconducting systems. Based on this formalism, we reveal the basic properties of BSP and CSP and their relationships. The BSP describes the intrinsic spin polarized properties of devices. The CSP depends on both intrinsic parameters of device and the incident current. For the non-spin-polarized incident current with the inphase spin-phase coherence, CSP equals to BSP. We give analytically the BSP and CSP of several typical nanodevice models, ferromagnetic nanowire, Rashba nanowire and rings. These results provide basic physical behaviors of BSP and CSP and their relationships.
description: 18 pages
Quartierspiegel Saatlen 2020
Creators: name: (:Unkn) Unknown
Publisher: name: Zentralbibliothek Zürich
Year: 2020
Subjects: subject: 314 Allgemeine Statistiken zu Europa
subject: 710 Städtebau, Raumplanung, Landschaftsgestaltung
subject: 949 Geschichte anderer Teile Europas
subject: Zürich-Schwamendingen
subject: Quartier
subject: Amtliche Statistik
subject: Bevölkerungsstatistik

description: Die in dieser Ausgabe publizierten Daten beziehen sich zum grössten Teil auf folgenden Zeitabschnitt : 2019
description: Das Quartier Saatlen steht weniger für Urbanität als für das lauschige Lebensgefühl einer Gartenstadt: Die Vorgärten der in Zeilenstruktur gebauten Einfamilienhäuser verleihen der Gegend ihren grünen Charakter. Nicht ganz so idyllisch nehmen sich dagegen die von der Autobahn verursachten Immissionen aus, doch Entlastung ist in Sicht.
Narration in Academic Language. A Corpus Linguistic Approach Based on Verb Morphology
Creators: name: Andresen, Melanie
Publisher: name: Zenodo
Year: 2022
Subjects: corpus linguistics
narration
academic language
tense

description: Slides of my presentation at DGfS 2022 in the workshop "Narration in context" (see https://sfb1412.hu-berlin.de/narration-in-context/)
Early Results from VLT-SPHERE: Long-Slit Spectroscopy of 2MASS 0122-2439B, a Young Companion Near the Deuterium Burning Limit
Creators: name: Hinkley, Sasha
name: Bowler, Brendan P.
name: Vigan, Arthur
name: Aller, Kimberly M.
name: Liu, Michael C.
name: Mawet, Dimitri
name: Matthews, Elisabeth
name: Wahhaj, Zahed
name: Kraus, Stefan
name: Baraffe, Isabelle
name: Chabrier, Gilles
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present 0.95-1.80 $μ$m spectroscopy of the $\sim$12-27 $M_{\rm Jup}$ companion orbiting the faint ($R$$\sim$13.6), young ($\sim$120 Myr) M-dwarf 2MASS J01225093--2439505 ("2M0122--2439 B") at 1.5 arcsecond separation (50 AU). Our coronagraphic long-slit spectroscopy was obtained with the new high contrast imaging platform VLT-SPHERE during Science Verification. The unique long-slit capability of SPHERE enables spectral resolution an order of magnitude higher than other extreme AO exoplanet imaging instruments. With a low mass, cool temperature, and very red colors, 2M0122-2439 B occupies a particularly important region of the substellar color-magnitude diagram by bridging the warm directly imaged hot planets with late-M/early-L spectral types (e.g. $β$ Pic b and ROXs 42Bb) and the cooler, dusty objects near the L/T transition (e.g. HR 8799bcde and 2MASS 1207b). We fit BT-Settl atmospheric models to our $R$$\approx$350 spectrum and find $T_{\rm eff}$=1600$\pm$100 K and $\log(g)$=4.5$\pm$0.5 dex. Visual analysis of our 2M0122-2439 B spectrum suggests a spectral type L3-L4, and we resolve shallow $J$-band alkali lines, confirming its low gravity and youth. Specifically, we use the Allers & Liu (2013) spectral indices to quantitatively measure the strength of the FeH, VO, KI, spectral features, as well as the overall $H$-band shape. Using these indices, along with the visual spectral type analysis, we classify 2M0122-2439 B as an intermediate gravity (INT-G) object with spectral type L3.7$\pm$1.0.
description: Accepted to ApJ Letters, 8 pages, 4 figures, some minor typographical issues were fixed
Floodwater farming, discontinuous ephemeral streams, and Puebloan abandonment in southwestern Colorado
Creators: name: Huckleberry G.A.
name: Billman B.R.
Publisher: name: Society for American Archaeology
Year: 1998

description: Geoarchaeological study on the southern piedmont of Sleeping Ute Mountain in southwestern Colorado indicates the presence of discontinuous ephemeral streams that were the foci of episodic Puebloan occupation between A.D. 600s and 1280. Characterized by arroyos, discontinuous ephemeral streams contain alternating aggrading and degrading reaches and are well suited for ak chin floodwater agriculture. Episodic Puebloan abandonment of the southern piedmont correlates with periods of drought but does not appear to be linked to stream entrenchment. We question a priori assumptions of droughts correlated to stream entrenchment and urge caution in the use of drought-arroyo models for settlement shifts in alluvial flood plains without supporting stratigraphic or geomorphic evidence.
Effective Use of Human Computer Interaction in Digital Academic Supportive Devices
Creators: name: Thuseethan, S.
name: Kuhanesan, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: In this research, a literature in human-computer interaction is reviewed and the technology aspect of human computer interaction related with digital academic supportive devices is also analyzed. According to all these concerns, recommendations to design good human-computer digital academic supportive devices are analyzed and proposed. Due to improvements in both hardware and software, digital devices have unveiled continuous advances in efficiency and processing capacity. However, many of these systems are also becoming larger and increasingly more complex. Although such complexity usually poses no difficulties for many users, it often creates barriers for academic users while using digital devices. Usually, in designing those digital devices, the human-computer interaction is left behind without consideration. To achieve dependable, usable, and well-engineered interactive digital academic supportive devices requires applied human computer interaction research and awareness of its issues.
ULTRATHIN INDIUM-BASED SEMICONDUCTORS FOR BACK-END-OF-LINE LOGIC AND MEMORY APPLICATIONS
Creators: name: Zheng, Dongqi
Publisher: name: Purdue University Graduate School
Year: 2023
Subjects: Microelectronics
Radio frequency engineering
Compound semiconductors
Nanoelectronics

description: As the semiconductor technology pushed to 3 nm node and beyond, more and more effort has been input on the investigation of advanced device structures and package technologies such as gate-all-around, vertical stack, and monolithic 3D etc., as well as innovation of ultrathin materials including van der Waals 2D materials and atomically thin oxide semiconductors. Among them, Back-end-of-line compatible materials and devices for logic and memory have been attracting more and more attention due to the quantifiable performance and energy efficiency advantages application in Monolithic 3-D Integration. Indium-based compound semiconductors, in the form of either amorphous or crystalline, is an emerging material platform with outstanding electrical and optoelectronic properties. In this dissertation, we will focus on novel Indium-based (In2X3, X= O, Se…) based material system, especially the theoretical investigation and experimental effort from material growth to various device characterizations and applications. Systematic investigation is performed on low-thermal-budget Zn or W-doped In2O3 down to 40 nm channel lengths revealing excellent transistor characteristics including on currents approaching 1.5 A/mm because of unique band alignment, close to the ideal 60 mV/dec subthreshold swing from the high-quality interface, and high on/off ratios of 1012 due to the wide bandgap. Meanwhile, record-high positive-bias-stress stability is achieved by ultrathin Zn-doped In2O3 thin-film transistors with negligible threshold voltage shift (-16 mV) and high-frequency GHz operation enabling perfect alignment with CMOS logic voltages and clock frequencies. Beyond indium oxide, In2Se3 also show excellent semiconductor and ferroelectric features. 3 nm, mm-scale size continuous films can be grown and transferable perfectly to meet the BEOL process temperature requirement and ultrathin van der Waals In2Se3/p+ Si asymmetric ferroelectric semiconductor junctions is fabricated with high current density/distinction ratio targeting next-generation ultra-dense memory applications. A model of the depletion-assisted ferroelectric switch for 2D FE semiconductors is proposed and simulated to explain the presence of ferroelectricity in semiconducting In2Se3. These works lay out the foundation for hyper-scaling electronic devices with enhanced functionality design in the post-Moore’s law era.