cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Effect of COVID-19 on antenatal care: experiences of medical professionals in the Netherlands
Creators: name: Gamberini, Carlotta
name: Angeli, Federica
name: Knight, Lucia
name: Zaami, Mariama
name: Al-Nasiry, Salwan
name: Ambrosino, Elena
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Document Analysis Data Collection Tool (.doc). Data collection and interpretation tool that was used to carry out the content and thematic analysis of guidelines.
An Examination of Virtual Fencing as a Tool to Manage Beef Heifers and Cow-calf Pairs in Western Canada
Creators: Harland, Alexandra J.
Publisher: name: University of Alberta Library
Year: 2024

This study encompasses the evaluation of Nofence virtual fencing (VF) technology for managing grazing cattle in western Canada, addressing both technical performance and animal behavior. Two key investigations were conducted: one focusing on the technical efficacy of VF collars during summer and winter conditions in a northern temperate climate, and the other exploring cattle behavior and learning within VF rotational grazing systems. Key metrics of the technical performance study included network connectivity, collar failures, and battery and solar charging performance. The findings indicated robust network connectivity with mean connection intervals well within the expected limits and minimal connectivity issues. Collar failures were infrequent, primarily due to network connection problems and physical loss. Battery performance remained strong, maintaining high charge levels even during winter with limited daylight. These results highlight VF's potential to reduce fencing costs and enhance grazing management in western Canadian environments, provided reliable cellular network access. The second study examined the training and compliance of heifers and first-calf cows with VF technology during rotational grazing. Heifers learned to comply with VF boundaries within 5-7 days, with a mean ratio of electrical stimuli to audio cues (E:A) of 17.9% (±18.4) during training decreasing to 5.2% (±11.2) during rotational grazing. Cows with calves at side, previously experienced with VF, received an E:A ratio of less than 2.5% during re-training and rotational grazing. All animals were successfully contained by VF boundaries more than 99% of the time. No significant associations were present between the number of VF stimuli, and animal characteristics and performance. Grazing pressure and stocking rate influenced the number of VF stimuli received and the duration of audio cues. The study concludes that VF technology effectively manages rotational grazing, with cattle demonstrating learning and compliance to VF boundaries. Further research is needed to explore the effects of higher stocking rates, grazing pressure, and intrinsic animal characteristics. Combined, these studies demonstrate the technical viability of VF technology during summer and winter in western Canada and its effectiveness in managing cattle behavior and grazing patterns. VF technology offers significant benefits for cost reduction, management flexibility, and sustainable use of rangelands in the Canadian beef industry, contingent on adequate network connectivity and thoughtful implementation.
Examining Bio-Inspired Approaches for Continual Reinforcement Learning
Creators: Mastikhina, Olya
Publisher: name: University of Alberta Library
Year: 2024

Despite the brain's inherent ability to continually learn, biological insights are rarely applied to continual reinforcement learning (RL).

This thesis addresses this gap by examining four under-investigated biologically-inspired modifications within the context of continual RL: energy minimization, wire length constraints, sparse distributed memory multilayer perceptrons, and fuzzy tiling activations. We show that some of these modifications help increase plasticity and generalization as well as slightly decrease catastrophic forgetting. We additionally provide an analysis of the learned representations.
Advancing Log Anomaly Detection by Deep Log Modeling
Creators: Lin, Yifei
Publisher: name: University of Alberta Library
Year: 2024

Nowadays systems logs are crucial for ensuring the reliability and security of modern computer systems. Effective log anomaly detection is essential for identifying potential threats and maintaining system integrity. Many existing unsupervised methods depend on additional abnormal data for hyperparameter selection or auxiliary datasets for discriminative model optimization, limiting their practical application. Moreover, current log anomaly detection methods are often static, offline, and struggle with the dynamic and evolving nature of real-world environments. They require extensive preprocessing and frequent retraining, which is resource-intensive and inefficient in handling non-stationary data distributions. This thesis addresses the challenges of log anomaly detection with two novel approaches: FastLogAD and LogREAD, which focus on offline and online anomaly detection, respectively.FastLogAD is designed for offline log sequence anomaly detection, emphasizing both speed and accuracy. By employing a Mask-Guided Anomaly Generator (MGAG) to produce pseudo-anomalies and a Discriminative Abnormality Separation (DAS) network to distinguish these from normal logs, FastLogAD effectively mitigates the dependency on additional training data. Experimental results on HDFS, BGL, and Thunderbird datasets demonstrate that FastLogAD not only achieves superior F1-Scores but also significantly enhances detection speed compared to existing methods.Conversely, LogREAD focuses on online continual log instance anomaly detection, adapting to evolving data distributions without extensive preprocessing. This parsing-free method utilizes an adaptively reduced memory bank and a continuously evolved feature extractor to manage dynamic log patterns. Evaluations reveal that LogREAD performs comparably to, or better than current offline methods and outperforms all online methods, showcasing its robustness in both static and dynamic environments.Together, FastLogAD and LogREAD offer comprehensive solutions for diverse log anomaly detection scenarios. FastLogAD excels in high-throughput offline detection, while LogREAD provides adaptive real-time monitoring. This thesis contributes to advancing the field of log anomaly detection by addressing key challenges such as non-stationarity, data imbalance, and the need for rapid anomaly identification. Future developments in creating a generalized model adapting to a broad range of systems following our work would extend its applicability in real-world scenarios.
Supplemental_material – Supplemental material for Gender (Conformity) Matters: Cross-Dimensional and Cross-Modal Associations in Sexual Orientation Perception
Creators: name: Kachel, Sven
name: Steffens, Melanie C.
name: Preuß, Sabine
name: Simpson, Adrian P.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Supplemental_material for Gender (Conformity) Matters: Cross-Dimensional and Cross-Modal Associations in Sexual Orientation Perception by Sven Kachel, Melanie C. Steffens, Sabine Preuß and Adrian P. Simpson in Journal of Language and Social Psychology
PSYCHOLOGICAL MECHANISMS SHAPING SOCIAL-PSYCHOLOGICAL FACTORS IN BUSINESS LEADERSHIP ACTIVITIES
Creators: name: Sobirova, Anora
Publisher: name: Zenodo
Year: 2024

description: In this article, the adaptation of internal psychological factors that ensure the effectiveness of entrepreneurial activity to specific social and psychological conditions, and their dependence on the individual’s primary motivations, have been studied using scientific methods. Additionally, based on the aforementioned factors, the role of social psychology in studying the real psychological mechanisms of entrepreneurial motivation among today’s youth is discussed.
Supplementary document for A strong electroluminescence from SnO2 nanocrystals and Er3+ co-doped silica thin film via introducing Ca2+ - 6575547.pdf
Creators: name: Zhao, Jingjie
name: Zhang, Yangyi
name: Wang, Lixiang
name: Chen, Jiaming
name: Li, Dongke
name: Qu, Enze
name: Xu, Jun
name: chen, kunji
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Hope and the Lived Experience of Parkinson’s Disease: A Qualitative Meta-synthesis
Creators: Murdoch, Kenneth C
Publisher: name: University of Alberta Library
Year: 2024

This meta-synthesis study aimed to answer the research question: How is hope reflected in the phenomenological literature on the lived experience of PD? Utilizing Sandelowski and Barroso’s (2007) method for meta-synthesis reviews and an analytic strategy informed by thematic synthesis and thematic analysis (Braun & Clarke, 2012; Thomas & Harden, 2008), 31 phenomenological studies were selected and synthesized in answer to the research question. The findings of this review are based on a total sample of 289 individuals with PD (male = 142, female = 146, unknown = 1). The sample sizes of the individual phenomenological studies ranged from one participant to 14 (M=8.5), with ages ranging from 30 - 86. Five categories were constructed based on these 31 studies: (a) Encounters in the Medical Context: Hope and Hopelessness in PD (b) Unfamiliar Being: Hope Wilted, Strengthened, and Transformed; (c) Being Seen: Hope Reflected Through Relationships (d) Enacting Hope (e) (Re)Constructing Hopeful Narratives. These findings were explored for theoretical and clinical implications for medicine and counselling psychology. Lastly, theoretical linkages were made between the findings and avenues of hope and PD research. Findings from this study may be used to offer concrete recommendations for clinicians to enhance their sensitivity and knowledge concerning the lived experience of PD patients.
Additional file 1 of Factors associated with inadequate receipt of components and non-use of antenatal care services in India: a regional analysis
Creators: name: Nagdev, Nilu
name: Ogbo, Felix Akpojene
name: Dhami, Mansi Vijaybhai
name: Diallo, Thierno
name: Lim, David
name: Agho, Kingsley E.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Cardiology

description: Additional file 1: Supplementary Table 1. Definition and categorisation of potential variables used in the study.
Serving the Greater Good With Less: Survey Experiment on How Public Service Motivation Shapes Perception of Staff Shortages
Creators: name: Kim, P
name: Cho, Wonhyuk
name: Kim, D
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2025
Subjects: classificationCode: 35
subject: Commerce, management, tourism and services
classificationCode: 4408
subject: Political science
subject: FOS: Political science
classificationCode: 3505
subject: Human resources and industrial relations
classificationCode: 3507
subject: Strategy, management and organisational behaviour
classificationCode: 4407
subject: Policy and administration
classificationCode: 44
subject: Human society

description: Personnel shortages are presenting significant challenges for many municipalities, as well-qualified civil servants in smaller cities and non-urban areas leave their positions. Given this dynamic, understanding how local government employees perceive staff shortages is key to designing effective strategies for promoting staff well-being and productivity. This article analyzes the influence of public service motivation (PSM) on shaping the perceptions of job demand and resources in local governments, through an experimental design (n = 120) and a survey of local government employees (n = 414), and further interprets the findings through semi-structured interviews. The experiment results show evidence of bi-directional effects—activating PSM heightened the perceived severity of staff burnout, while simultaneously lowering the perceived need for increased manpower. These findings suggest that PSM may raise an individual’s expectations of their job, which is possibly associated with feelings of frustration with current demands in local government. Conversely, the reduced perception of the need for additional manpower may show an increased sense of responsibility toward the job and willingness to overstretch for the local communities they serve. The employee survey results show that perceptions of the causes and solutions of staff shortages vary depending on their managerial rank, years of experience, and marital status.
A systematic revision of the genus Prognathodon (Squamata: Mosasauridae)
Creators: Mohr, Sydney R
Publisher: name: University of Alberta Library
Year: 2024

Mosasaurs are an extinct group of large aquatic lizards that swam the world’s oceans during the late Cretaceous, approximately 94 to 66 million years ago. The genus Prognathodon is a diverse subgroup of medium to large-sized mosasaurs with a unique set of features that have made it difficult for researchers to classify amongst other major mosasaurs groups. Furthermore, multiple analyses attempting to classify Prognathodon typically find highly inconsistent patterns of relationship and often part of a poorly resolved clade comprising of other mosasaur genera. A critical examination of the historical conceptualization of Prognathodon finds a series of recurring issues in the diagnoses and descriptions of both the type species and referred taxa, underpinning the need for a broad systematic reassessment of the group. A detailed re-evaluation of type species, Prognathodon solvayi, recognizes several newly identified osteological characters and provided a precise diagnosis that established a well-defined and informative concept of the taxon. A comparison between the emended diagnosis and the morphological characteristics of six referred species forms hypotheses as to their validity as members within Prognathodon. A single species, Prognathodon giganteus, bears strong enough resemblance to warrant synonymizing it with the type species. All other taxa deviate from the generic diagnosis to a great enough degree that supported their exclusion from the group. A phylogenetic analysis further tests these assumptions by incorporating a set of updated and new data based on the morphological assessment of Prognathodon. The resulting trees both recover Prognathodon solvayi as the sole member of the genus Prognathodon and support the referral of Prognathodon giganteus to the type species. Informed by morphological comparisons, the remaining referred taxa that fell outside Prognathodon were assigned to different genera. Although precisely how Prognathodon fits into the larger context of other major mosasaur groups remains unclear, the integration between a comprehensive morphological review and phylogenetic analysis nevertheless provided a coherent model of the genus and improved understanding of the internal systematic relationships of the group as a whole.
Appendix_A – Supplemental material for Work–game balance: Work interference, social capital, and tactical play in a mobile massively multiplayer online real-time strategy game
Creators: name: Lu, Anya Hommadova
name: Carradini, Stephen
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, Appendix_A for Work–game balance: Work interference, social capital, and tactical play in a mobile massively multiplayer online real-time strategy game by Anya Hommadova Lu and Stephen Carradini in New Media & Society
The "business of human rights"? Exploring the social practice of corporate accountability under the UN guiding principles on business and human rights
Creators: name: McVey, Marisa Cait
Publisher: name: University of St Andrews
Year: 2021
Subjects: subject: HD60.M3
subject: United Nations Human Rights Council
subject: Social responsibility of business
subject: Human rights

description: Attempts to ensure corporate accountability for human rights are numerous and diverse. The UN Guiding Principles for Business and Human Rights (UNGPs) have become the reference point for businesses to demonstrate their understanding of human rights responsibilities and enhance corporate accountability through human rights due diligence (HRDD). The UNGPs, which are ostensibly a soft law initiative, have inspired numerous global and national policies, and are being increasingly ‘hardened’ through national and supranational legislation. Precisely because of their popularity and endorsement, it is imperative that a critical analysis of their application is undertaken. However, at present there is a lack of empirical research that draws attention to how the UNGPs are implemented within the corporate context, or on the role of external human rights experts in this process. In order to provide insights into this aspect of their implementation, this exploratory study draws on two multinational case studies – an oil and gas company and a bank. The research utilises a conceptual framework informed by the social practice of accountability, and is underpinned by a social constructionist qualitative methodological research design. Findings suggest that translating human rights through the UNGPs into the corporate space is both a challenging and iterative exercise, which can lead to instances were human rights are regarded as manageable objects rather than realised. External experts must respond to a range of legitimacy claims to become experts in the business and human rights ecosystem, and while doing so may confer legitimacy onto MNCs’ human rights practices. Their roles are diverse and impactful and the expert industry itself appears to be increasingly competitive, as new actors enter this space. As such, this research provides a much-needed contribution to the expansion of interdisciplinary inquiry into business and human rights issues, evaluating the use of the UNGPs as an accountability mechanism and on the realities and nuances of ‘doing’ corporate accountability for human rights.
APPROVED_Xeomin_Prescribing_information_UKIE_combined_June_2019_v4 – Supplemental material for The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®)
Creators: name: Morgante, Francesca
name: Bavikatte, Ganesh
name: Anwar, Fahim
name: Biju Mohamed
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, APPROVED_Xeomin_Prescribing_information_UKIE_combined_June_2019_v4 for The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®) by Francesca Morgante, Ganesh Bavikatte, Fahim Anwar and Biju Mohamed in Therapeutic Advances in Neurological Disorders
Supplementary document for Design, Optimization and Characterization of Deep Sub-Wavelength Evanescent Orders in Terahertz Metagratings - 6575627.pdf
Creators: name: Rane, Shreeya
name: Punjal, Ajinkya
name: Prabhu, Shriganesh
name: Chowdhury, Dibakar Roy
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized
Photonics, Optoelectronics and Optical Communications

description: Supplementary materials
TCP883261_suppl_mat – Supplemental material for Measuring Whiteness: A Systematic Review of Instruments and Call to Action
Creators: name: R. C. Schooley
name: Debbiesiu L. Lee
name: Spanierman, Lisa B.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, TCP883261_suppl_mat for Measuring Whiteness: A Systematic Review of Instruments and Call to Action by R. C. Schooley, Debbiesiu L. Lee and Lisa B. Spanierman in The Counseling Psychologist
JHS890284 Supplemental Material1 - Supplemental material for Patient’s satisfaction beyond hand function in Dupuytren’s disease: analysis of 1106 patients
Creators: name: Poelstra, Ralph
name: Kooij, Yara E. Van
name: Oest, Mark J. W. Van Der
name: Slijper, Harm P.
name: Hovius, Steven E. R.
name: Selles, Ruud W.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, JHS890284 Supplemental Material1 for Patient’s satisfaction beyond hand function in Dupuytren’s disease: analysis of 1106 patients by Ralph Poelstra, Yara E. van Kooij, Mark J. W. van der Oest, Harm P. Slijper, Steven E. R. Hovius, Ruud W. Selles and the Hand-Wrist Study Group in Journal of Hand Surgery (European Volume)
The_Effect_of_Mental_Health_on_Violent-Behavioral_Outcomes_-_Supplementary_Material_1 – Supplemental material for Do Community Structural Characteristics Moderate the Association Between Mental Health and the Frequency and Severity of Violent-Behavioral Outcomes in Community Respondents?
Creators: name: Shaffer, Catherine S.
name: Douglas, Kevin S.
name: Fuller, Erin K.
name: Blanchard, Adam J. E.
name: Viljoen, Jodi L.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, The_Effect_of_Mental_Health_on_Violent-Behavioral_Outcomes_-_Supplementary_Material_1 for Do Community Structural Characteristics Moderate the Association Between Mental Health and the Frequency and Severity of Violent-Behavioral Outcomes in Community Respondents? by Catherine S. Shaffer, Kevin S. Douglas, Erin K. Fuller, Adam J. E. Blanchard and Jodi L. Viljoen in Journal of Interpersonal Violence
HEB826284_Supplemental_Appendix_A – Supplemental material for Mental Contrasting With Implementation Intentions Reduces Drinking When Drinking Is Hazardous: An Online Self-Regulation Intervention
Creators: name: Wittleder, Sandra
name: Kappes, Andreas
name: Oettingen, Gabriele
name: Gollwitzer, Peter M.
name: Jay, Melanie
name: Morgenstern, Jon
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, HEB826284_Supplemental_Appendix_A for Mental Contrasting With Implementation Intentions Reduces Drinking When Drinking Is Hazardous: An Online Self-Regulation Intervention by Sandra Wittleder, Andreas Kappes, Gabriele Oettingen, Peter M. Gollwitzer, Melanie Jay and Jon Morgenstern in Health Education & Behavior
Data-driven ion-independent relative biological effectiveness modeling using the beam quality Q
Creators: name: Tian, Liheng
name: Lühr, Armin
Publisher: name: TU Dortmund
Year: 2023
Subjects: subject: ion therapy
subject: RBE modeling
subject: beam quality
subject: LET
subject: proton therapy
subject: 530

description: Beam quality Q = Z2/E (Z = ion charge, E = energy), an alternative to the conventionally used linear energy transfer (LET), enables ion-independent modeling of the relative biological effectiveness (RBE) of ions. Therefore, the Q concept, i.e. different ions with similar Q have similar RBE values, could help to transfer clinical RBE knowledge from better-studied ion types (e.g. carbon) to other ions. However, the validity of the Q concept has so far only been demonstrated for low LET values. In this work, the Q concept was explored in a broad LET range, including the so-called overkilling region. The particle irradiation data ensemble (PIDE) was used as experimental in vitro dataset. Data-driven models, i.e. neural network (NN) models with low complexity, were built to predict RBE values for H, He, C and Ne ions at different in vitro endpoints taking different combinations of clinically available candidate inputs: LET, Q and linear-quadratic photon parameter αx/βx. Models were compared in terms of prediction power and ion dependence. The optimal model was compared to published model data using the local effect model (LEM IV). The NN models performed best for the prediction of RBE at reference photon doses between 2 and 4 Gy or RBE near 10% cell survival, using only αx/βx and Q instead of LET as input. The Q model was not significantly ion dependent (p > 0.5) and its prediction power was comparable to that of LEM IV. In conclusion, the validity of the Q concept was demonstrated in a clinically relevant LET range including overkilling. A data-driven Q model was proposed and observed to have an RBE prediction power comparable to a mechanistic model regardless of particle type. The Q concept provides the possibility of reducing RBE uncertainty in treatment planning for protons and ions in the future by transferring clinical RBE knowledge between ions.
description: Physics in medicine and biology;68(10)
Additional file 2 of Factors associated with inadequate receipt of components and non-use of antenatal care services in India: a regional analysis
Creators: name: Nagdev, Nilu
name: Ogbo, Felix Akpojene
name: Dhami, Mansi Vijaybhai
name: Diallo, Thierno
name: Lim, David
name: Agho, Kingsley E.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Cardiology

description: Additional file 2: Table S1. Factors associated with no ANC in North India states. Table S2. Factors associated with no ANC in South India states. Table S3. Factors associated with no ANC in East India states. Table S4. Factors associated with no ANC in West India states. Table S5. Factors associated with no ANC in Central India states. Table S6. Factors associated with no ANC in Northeast India states.
The lysosomotropic agent siramesine induces cell death in prostate cancer cells and synergizes with the tyrosine kinase inhibitor lapatinib
Creators: Bhatti, Ilsa
Publisher: name: University of Alberta Library
Year: 2024

Prostate cancer is the most diagnosed cancer affecting Canadian men. Prostate tumors that progress from localized disease to advanced stages show resistance to standard therapy, a major problem that requires alternative treatments. One new treatment possibility is targeting lysosomal membrane disruption with lysosomotropic agents, leading to lysosome membrane permeabilization (LMP) and triggering pathways that result in cell death. Lysosomotropic agents can also be combined with other targeted agents to increase the efficacy of cell death induction in different types of cancer. Previous research has shown that the most effective lysosomotropic agent for inducing ROS generation, lysosome membrane permeabilization, and cell death in prostate cancer cell lines is siramesine which inhibits acidic sphingomyelinase. My results indicate that combining siramesine with lapatinib, a tyrosine kinase inhibitor for EGFR and HER2, synergistically increased prostate cancer cell death. This combination induced cell death to a greater extent in an aggressive castration-resistant prostate cell line compared to an androgen-sensitive prostate cancer cell line or non-malignant cell line. The synergistic increase in cell death with the combination treatment is mediated by increased ROS levels following lysosome membrane permeabilization but is independent of the actions of Cathepsin D released after LMP and caspase activation. The combination also failed to result in BID cleavage. Combining siramesine and lapatinib resulted in decreased expression of MCL-1, a BCL-2 family member, and increased cellular and mitochondrial ROS. Treating cells with the antioxidant alpha-tocopherol attenuated the cell death resulting from siramesine alone or the combination treatment, suggesting a role for ROS in the caspase-independent cell death. In other cancer cells, siramesine induces autophagy (self-eating). I found that siramesine and lapatinib caused accumulation of the autophagic markers LC3-II and p62 and combining the combination treatment with chloroquine administration did not further increase expression indicating that siramesine and lapatinib fail to increase autophagic flux. This suggests the combination treatment inhibits autophagy and damage to the lysosome through siramesine prevents the progression of the autophagic pathway and subsequent degradation of the autophagic markers. These results indicate that combination treatments between lysosomotropic agents such as siramesine and targeted inhibitors such as the tyrosine kinase inhibitor lapatinib induce ROS driven cell death in prostate cancer cell lines, but that further work is needed to determine approved treatment options to target these pathways and provide an alternative treatment strategy in the management of drug resistant aggressive prostate cancers.
Supplementary_Methods_and_Results – Supplemental material for Gene Expression Profile Is Different between Intact and Enzymatically Digested Equine Articular Cartilage
Creators: name: Lepage, Sarah I. M.
name: Rishi Sharma
name: Dukoff, David
name: Stalker, Leanne
name: LaMarre, Jon
name: Koch, Thomas G.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, Supplementary_Methods_and_Results for Gene Expression Profile Is Different between Intact and Enzymatically Digested Equine Articular Cartilage by Sarah I. M. Lepage, Rishi Sharma, David Dukoff, Leanne Stalker, Jon LaMarre and Thomas G. Koch in CARTILAGE
Supplementary document for Super-Resolution-Chip: An In-Vitro Platform that enables Super-Resolution Microscopy of co-cultures and 3D systems - 6576056.pdf
Creators: name: Bonberg, Ronja
name: Weiss, Yifat
name: Sade, Ofir
name: Beldjilali-Labro, Megane
name: Leichtman-Bardoggo, Yeal
name: Talpir, Itay
name: Gottfried, Irit
name: Ashery, Uri
name: Rauti, Rossana
name: Maoz, Ben
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Biological Engineering
Biotechnology
Biological Techniques

description: SI Data
Automated Bioacoustic Monitoring for South African Bird Species on Unlabeled Data
Creators: name: Doell, Michael
name: Kuehn, Dominik
name: Suessle, Vanessa
name: Burnett, Matthew J.
name: Downs, Colleen T.
name: Weinmann, Andreas
name: Hergenroether, Elke
Publisher: name: arXiv
Year: 2024
Subjects: subject: Sound (cs.SD)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Analyses for biodiversity monitoring based on passive acoustic monitoring (PAM) recordings is time-consuming and challenged by the presence of background noise in recordings. Existing models for sound event detection (SED) worked only on certain avian species and the development of further models required labeled data. The developed framework automatically extracted labeled data from available platforms for selected avian species. The labeled data were embedded into recordings, including environmental sounds and noise, and were used to train convolutional recurrent neural network (CRNN) models. The models were evaluated on unprocessed real world data recorded in urban KwaZulu-Natal habitats. The Adapted SED-CRNN model reached a F1 score of 0.73, demonstrating its efficiency under noisy, real-world conditions. The proposed approach to automatically extract labeled data for chosen avian species enables an easy adaption of PAM to other species and habitats for future conservation projects.
description: preprint
Colloque gestion de crise et numérique : nouvelles menaces et nouvelles solutions
Creators: name: Benaben, Frederick
name: Debar, Hervé
name: Hassen Drira
name: Dusserre, Gilles
name: Jean-Max Dutertre
name: Francillon, Aurélien
name: Marc-Oliver Pahl
name: Pautet, Laurent
Publisher: name: Zenodo
Year: 2022
Subjects: gestion de crise
menaces
cybersécurité
solutions

description: La communauté IMT qui porte le colloque Risques et Cyber est en quelque sorte par nature transverse aux écoles des Mines et aux écoles des Télécom, en rassemblant des profils et des approches scientifiques assez différents. C’est donc une thématique qui illustre bien ce qu’on peut construire par le rassemblement des compétences de ces deux familles d'écoles. A travers l’ensemble des écoles, elle peut amener des compétences en cybersécurité, notamment en matière d’approches cybersécurité des systèmes, mais aussi en gestion de crise, que ce soit en simulation ou en modélisation, avec des approches numériques comme des approches relevant des sciences humaines et sociales. Si l’on ajoute les fortes compétences de nos écoles en ce qui concerne les systèmes industriels ou les systèmes de santé, mais aussi en modélisation et en optimisation, nous sommes capables d’apporter des réponses assez larges sur l’ensemble du spectre qui va de la détection à la résilience et à la remédiation, en passant par la gestion de crise.
title: Approaches towards a community-oriented and enabling disaster management model
Creators: name: Ohder, Claudius
name: Sticher, Birgitta
name: Hochschule Für Wirtschaft Und Recht Berlin
Publisher: name: Hochschule für Wirtschaft und Recht Berlin
Year: 2013

description: Forschungsprojekt „Katastrophenschutz-Leuchttürme als Anlaufstelle für die Bevölkerung in Krisensituationen“ (Kat-Leuchttürme)
Supplementary document for Surface topography detection based on optical differential metasurface - 6576237.pdf
Creators: name: Li, Qiuying
name: Yang, Hua
name: Wang, Yan
name: Shou, yichang
name: Liu, Shuoqing
name: Luo, Hailu
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Detailed theoretical derivation and complementary experiments
Long-term stability of two-stage aerobic granular sludge system for combined organic matter and nitrogen removal from aerobically digested centrate wastewater
Creators: Kong, Lu
Publisher: name: University of Alberta Library
Year: 2024

Nitrogen is an essential element for all living organisms and plays a key role in various biological processes. However, excessive nitrogen levels in the environment can lead to significant ecological issues, including water pollution and eutrophication, resulting in harmful algal blooms, oxygen depletion, and loss of aquatic life. Ammonia is the primary form of nitrogen compound in sewage and requires effective treatment in wastewater treatment plants. High ammonia and high chemical oxygen demand (COD) wastewater pose severe environmental threats, further exacerbating these issues. Effective and energy-efficient nitrogen removal technologies are essential to meet stringent discharge standards.

The overall objective of this thesis is to evaluate a two-stage moving bed biofilm reactor (MBBR) followed by an aerobic granular sludge (AGS) system developed to treat high COD and high ammonia biosolid autothermal thermophilic aerobic digestion (ATAD) centrate. The MBBR efficiently handled high organic loading rates (OLRs) exceeding 20 kg COD/m³/d and reduced the carbon to nitrogen (C/N) ratios from 6 to 3. Treated effluent was then processed in the AGS system, where nitrogen removal was primarily accomplished via the nitritation/denitritation pathway, with removal efficiencies reaching 98.9% for NH₄⁺-N and 91.7% for total inorganic nitrogen (TIN). After 200 days of operation, the AGS system had an optimized hydraulic retention time (HRT) of 10 hours and maintained a sludge volume index (SVI) between 40 to 80 mL/g, achieving a nitrogen treatment capacity of 1.77 kg N/m³/d. Ammonia oxidizing bacteria (AOB) demonstrated substantial nitrogen conversion efficiency, evidenced by nitrogen conversion rates of 0.57 ± 0.02 g N/g VSS/day and denitritation rates of 1.27 ± 0.01 g N/g VSS/day.
supplement – Supplemental material for A Novel Device for the Evacuation of Cerumen
Creators: name: Katzenell, Udi
name: Halperin, Doron
name: Tzofit Dahan
name: Bartov, Noam
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, supplement for A Novel Device for the Evacuation of Cerumen by Udi Katzenell, Doron Halperin, Tzofit Dahan and Noam Bartov in Annals of Otology, Rhinology & Laryngology
Additional file 2 of Patient characteristics associated with the acceptability of teleconsultation: a retrospective study of osteoporotic patients post-COVID-19
Creators: name: Pongiglione, Benedetta
name: Carrone, Flaminia
name: Angelucci, Alessandra
name: Mazziotti, Gherardo
name: Compagni, Amelia
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Additional file 2. Confirmatory factor analysis showing loading factors for questions in the modified SUTAQ.
CNN Based Flank Predictor for Quadruped Animal Species
Creators: name: Suessle, Vanessa
name: Heurich, Marco
name: Downs, Colleen T.
name: Weinmann, Andreas
name: Hergenroether, Elke
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The bilateral asymmetry of flanks of animals with visual body marks that uniquely identify an individual, complicates tasks like population estimations. Automatically generated additional information on the visible side of the animal would improve the accuracy for individual identification. In this study we used transfer learning on popular CNN image classification architectures to train a flank predictor that predicts the visible flank of quadruped mammalian species in images. We automatically derived the data labels from existing datasets originally labeled for animal pose estimation. We trained the models in two phases with different degrees of retraining. The developed models were evaluated in different scenarios of different unknown quadruped species in known and unknown environments. As a real-world scenario, we used a dataset of manually labeled Eurasian lynx (Lynx lynx) from camera traps in the Bavarian Forest National Park to evaluate the model. The best model, trained on an EfficientNetV2 backbone, achieved an accuracy of 88.70 % for the unknown species lynx in a complex habitat.
Additional file 3 of Patient characteristics associated with the acceptability of teleconsultation: a retrospective study of osteoporotic patients post-COVID-19
Creators: name: Pongiglione, Benedetta
name: Carrone, Flaminia
name: Angelucci, Alessandra
name: Mazziotti, Gherardo
name: Compagni, Amelia
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Additional file 3. Modified SUTAQ descriptors.
title: Hortensie :
title: Richtlinien für die Durchführung der Prüfung auf Unterscheidbarkeit, Homogenität und Beständigkeit.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants..,
Publisher: name: International Union for the Protection of New Varieties of Plants
Year: 0
Subjects: Group identity
New Varieties of Plants
Hydrangea

description: Zweck dieser Richtlinien („Prüfungsrichtlinien“) ist es, die in der Allgemeinen Einführung (Dokument TG/1/3) und deren verbundenen TGP-Dokumenten enthaltenen Grundsätze in detaillierte praktische Anleitung für die harmonisierte Prüfung der Unterscheidbarkeit, der Homogenität und der Beständigkeit (DUS) umzusetzen und insbesondere geeignete Merkmale für die DUS-Prüfung und die Erstellung harmonisierter Sortenbeschreibungen auszuweisen.
Supplementary document for Pol2Pol: Self-Supervised Polarimetric Image Denoising - 6577069.pdf
Creators: name: Liu, Hedong
name: Li, Xiaobo
name: Cheng, Zhenzhou
name: Liu, T.
name: Zhai, Jingsheng
name: Hu, Haofeng
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: The independence of noisy polarimetric image pairs
A Polynomial-Time Approximation Scheme for Traveling Salesman Problem with Neighborhoods Over Parallel Line Segments of Similar Length
Creators: Ghaseminia, Benyamin
Publisher: name: University of Alberta Library
Year: 2024

In this thesis, we consider the Traveling Salesman Problem with Neighborhoods (TSPN) on the Euclidean plane, and present a Polynomial-Time Approximation Scheme (PTAS) when the neighborhoods are parallel line segments with lengths between [1, λ] for any constant value λ.In TSPN (which generalizes classic TSP), each client represents a set (or neighborhood) of points in a metric and the goal is to find a minimum cost TSP tour that visits at least one point from each client set. In the Euclidean setting, each neighborhood is a region on the plane.TSPN is significantly more difficult than classic TSP even in the Euclidean setting.A notable case of TSPN is when each neighborhood is a line segment. Although there are PTAS's for when neighborhoods are fat objects (with limited overlap), TSPN over line segments is APX-hard even if all the line segments have unit length. For parallel (unit) line segments, the best approximation factor is 3√2 from 20 years ago.The PTAS we present, settles the approximability of this case of the problem. Our algorithm finds a (1 + ε)-factor approximation for an instance of the problem with n segments with lengths in [1, λ] in time n^O(λ/ε^3).
Accounting for Hyperparameter Tuning in Online Reinforcement Learning
Creators: Hakhverdyan, Anna
Publisher: name: University of Alberta Library
Year: 2024

Most work in online reinforcement learning (RL) tunes hyperparameters in an offline phase without accounting for the said interaction. This empirical methodology is a reasonable approach to assess how well algorithms can perform but is limited when evaluating algorithms for practical deployment in the real world. In many applications, the environment is incompatible with exhaustive hyperparameter searches, and typical evaluations do not characterize how much data one must use for such searches. We investigate how to do online tuning, where the agent must select hyperparameters during interactions. Hyperparameter tuning is part of the agent rather than a separate hidden phase. We layer the Bayesian optimizer over standard RL algorithms and assess behaviour when tuning hyperparameters online. We show the expected result - this strategy's success depends on the environment and the algorithm. We introduce a way of tuning that mitigates wasteful resetting and shows that it can achieve comparable but not better performance levels than the default values, highlighting the need for further development.
Carbon Isotope Exchange in Organic Acids and Related Decarboxylative Transformations
Creators: Doyle, Michael G. J.
Publisher: name: University of Alberta Library
Year: 2024

The synthesis of isotopically labeled organic molecules is vital for drug and agrochemical discovery and development, medical imaging, and the elucidation of biochemical processes. Carbon isotope exchange is emerging as a leading method to generate carbon-labeled targets, which are increasingly sought over the more commonly employed hydrogen-based labels due to their enhanced stability in biological systems. In particular, carboxylate exchange in organic acids with isotopically labeled carbon dioxide has become an attractive strategy for the late-stage (radio)labeling of complex drug targets and pharmaceuticals bearing carboxylic acids. Although tremendous progress has been made in this area over the past half-decade, certain classes of carboxylic acids remain incompatible with traditional carbon isotope exchange conditions.

This dissertation describes new strategies for carbon isotope exchange in α-amino acids and aliphatic organic acids. Radiolabeled racemic α-amino acids can be obtained directly from their native precursors using an aldehyde catalyst in conjunction with isotopically labeled carbon dioxide under thermal conditions (Chapter 2). This process was further adapted for the preparation of enantioenriched radiolabeled α-amino acids using a chiral aldehyde auxiliary (Chapter 3). Furthermore, metallaphotoredox catalysis enables direct carbon isotope exchange in aliphatic organic acids with isotopically labeled carbon dioxide in the presence of a phosphine (Chapter 4). The fundamentals and principles of decarboxylation in organic acids were also leveraged in an enantioselective decarboxylative benzylation process to prepare acyclic targets bearing stereogenic quaternary carbon centers (Chapter 5).
Raising the Bar: Better Psychological Report Models for Graduate Education
Creators: Taylor, Scott J.
Publisher: name: University of Alberta Library
Year: 2024

This study explored the readability and practical utility of psychological report samples from graduate-level textbooks. Psychological reports are vital in educational and healthcare settings, transforming complex assessments into actionable plans for teachers, therapists, clients, and families. Despite their importance, these reports often remain difficult to understand due to their complex language and structure. This study used quantitative readability statistics and qualitative content analysis to evaluate the clarity, client-centeredness, presentation styles, and data integration in the reports. Findings indicate that while there has been some progress towards more readable and user-friendly reports, significant challenges remain. Sample reports continue to often use technical language and a passive voice, making them less accessible to general

readers. Additionally, although some efforts have been made to enhance readability through bullet points and structured formats, the use of visuals and thematic organization is still limited. Many reports fail to integrate data effectively, simply restating test results without providing a cohesive narrative. This study highlights the need for continued efforts to improve the readability and utility of psychological report samples. Recommendations include enhancing training programs for graduate students, promoting the use of readability tools, and developing standardized templates.