cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex.
Creators: name: Merker, Matthias
name: Kohl, Thomas A
name: Barilar, Ivan
name: Andres, Sönke
name: Fowler, Philip W
name: Chryssanthou, Erja
name: Ängeby, Kristian
name: Jureen, Pontus
name: Moradigaravand, Danesh
name: Parkhill, Julian
name: Peacock, Sharon J
name: Schön, Thomas
name: Maurer, Florian P
name: Walker, Timothy
name: Köser, Claudio
name: Niemann, Stefan
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Mycobacterium tuberculosis
Drug resistance
Intrinsic Resistance
Benign Mutations

description: BACKGROUND:A comprehensive understanding of the pre-existing genetic variation in genes associated with antibiotic resistance in the Mycobacterium tuberculosis complex (MTBC) is needed to accurately interpret whole-genome sequencing data for genotypic drug susceptibility testing (DST). METHODS:We investigated mutations in 92 genes implicated in resistance to 21 anti-tuberculosis drugs using the genomes of 405 phylogenetically diverse MTBC strains. The role of phylogenetically informative mutations was assessed by routine phenotypic DST data for the first-line drugs isoniazid, rifampicin, ethambutol, and pyrazinamide from a separate collection of over 7000 clinical strains. Selected mutations/strains were further investigated by minimum inhibitory concentration (MIC) testing. RESULTS:Out of 547 phylogenetically informative mutations identified, 138 were classified as not correlating with resistance to first-line drugs. MIC testing did not reveal a discernible impact of a Rv1979c deletion shared by M. africanum lineage 5 strains on resistance to clofazimine. Finally, we found molecular evidence that some MTBC subgroups may be hyper-susceptible to bedaquiline and clofazimine by different loss-of-function mutations affecting a drug efflux pump subunit (MmpL5). CONCLUSIONS:Our findings underline that the genetic diversity in MTBC has to be studied more systematically to inform the design of clinical trials and to define sound epidemiologic cut-off values (ECOFFs) for new and repurposed anti-tuberculosis drugs. In that regard, our comprehensive variant catalogue provides a solid basis for the interpretation of mutations in genotypic as well as in phenotypic DST assays.
A qualitative study of design stakeholders' views of developing and implementing a registry-based learning health system.
Creators: name: Dixon-Woods, Mary
name: Campbell, Anne
name: Chang, Trillium
name: Martin, Graham
name: Georgiadis, Alexandros
name: Heney, Veronica
name: Chew, Sarah
name: Van Citters, Aricca
name: Sabadosa, Kathryn A
name: Nelson, Eugene C
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Replication
Quality improvement
Qualitative
Cystic Fibrosis
Registries
Co-production
Learning Health Systems
Program Theory

description: BACKGROUND:New opportunities to record, collate, and analyze routine patient data have prompted optimism about the potential of learning health systems. However, real-life examples of such systems remain rare and few have been exposed to study. We aimed to examine the views of design stakeholders on designing and implementing a US-based registry-enabled care and learning system for cystic fibrosis (RCLS-CF). METHODS:We conducted a two-phase qualitative study with stakeholders involved in designing, implementing, and using the RCLS-CF. First, we conducted semi-structured interviews with 19 program personnels involved in design and delivery of the program. We then undertook 11 follow-up interviews. Analysis of interviews was based on the constant comparative method, supported by NVivo software. RESULTS:The organizing principle for the RCLS-CF was a shift to more partnership-based relationships between patients and clinicians, founded in values of co-production, and facilitated by technology-enabled data sharing. Participants proposed that, for the system to be successful, the data it collects must be both clinically useful and meaningful to patients and clinicians. They suggested that the prerequisites included a technological infrastructure capable of supporting data entry and joint decision-making in an accessible way, and a set of social conditions, including willingness from patients and clinicians alike to work together in new ways that build on the expertise of both parties. Follow-up interviews highlighted some of the obstacles, including technical challenges and practical constraints on refiguring relationships between clinicians and patients. CONCLUSIONS:The values and vision underlying the RCLS-CF were shared and clearly and consistently articulated by design stakeholders. The challenges to realization were often not at the level of principle, but were both practical and social in character. Lessons from this study may be useful to other systems looking to harness the power of "big data" registries, including patient-reported data, for care, research, and quality improvement.
Recent trends and predictors of multimodality treatment for oesophageal, oesophagogastric junction, and gastric cancer: A Dutch cohort-study
Creators: name: Trip, Anouk K.
name: Stiekema, Jurriën
name: Visser, Otto
name: Dikken, Johan L.
name: Cats, Annemieke
name: Boot, Henk
name: Sandick, Johanna W. Van
name: Jansen, Edwin P. M.
name: Verheij, Marcel
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Pharmacology
subject: Medicine

description: Background. In recent years, evidence supporting multimodality treatment for oesophageal, oesophagogastric junction (OGJ), and gastric cancer has accumulated. This population-based cohort-study investigates trends and predictors of utilisation of multimodality treatment for oesophagogastric cancer in the Netherlands.Patients and methods. Data were obtained from the Netherlands Cancer Registry regarding patients with oesophageal (n = 5450), OGJ (n = 2168) and gastric cancer (n = 6683) without distant metastases who had undergone R0 or R1 surgery diagnosed between 2000 and 2012. Follow-up was completed until February 2014. Preoperative/postoperative chemotherapy and/or radiotherapy combined with surgery were considered multimodality treatment. Logistic regression analysis was performed to analyse the association of age, gender, socioeconomic status, clinical T and N classification, hospital type, comprehensive cancer centre network region, and year of diagnosis, with multimodality treatment receipt. Additional analyses were performed to explore differences in trends of utilisation of multimodality treatment between academic and non-academic hospitals.Results. Multimodality treatment utilisation for oesophageal, OGJ and gastric cancer increased significantly to 90%, 85% and 56% in 2012, respectively. In oesophageal and OGJ cancer patients, preoperative chemoradiotherapy was most frequently administered (85% and 47% in 2012, respectively), and in gastric cancer patients preoperative chemotherapy (47% in 2012). Lower age, higher clinical T and N classification, and diagnosis in more recent years were significantly associated with more frequent multimodality treatment receipt. The adoption of most types of multimodality treatment in academic hospitals preceded non-academic hospitals by a year.Conclusion. In the Netherlands, the utilisation of multimodality treatment for oesophagogastric cancer has significantly increased during the past decade, especially in oesophageal and OGJ cancer. Multimodality treatment utilisation was especially dependent on patient and tumour characteristics and year of diagnosis, but multimodality treatment trends seem to be related to the publication of landmark studies, participation in nationally running clinical trials, and hospital type, preceding national guidelines.
Hybridizing Traditional and Next-Generation Reservoir Computing to Accurately and Efficiently Forecast Dynamical Systems
Creators: name: Chepuri, Ravi
name: Amzalag, Dael
name: Antonsen, Thomas
name: Girvan, Michelle
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Reservoir computers (RCs) are powerful machine learning architectures for time series prediction. Recently, next generation reservoir computers (NGRCs) have been introduced, offering distinct advantages over RCs, such as reduced computational expense and lower training data requirements. However, NGRCs have their own practical difficulties, including sensitivity to sampling time and type of nonlinearities in the data. Here, we introduce a hybrid RC-NGRC approach for time series forecasting of dynamical systems. We show that our hybrid approach can produce accurate short term predictions and capture the long term statistics of chaotic dynamical systems in situations where the RC and NGRC components alone are insufficient, e.g., due to constraints from limited computational resources, sub-optimal hyperparameters, sparsely-sampled training data, etc. Under these conditions, we show for multiple model chaotic systems that the hybrid RC-NGRC method with a small reservoir can achieve prediction performance approaching that of a traditional RC with a much larger reservoir, illustrating that the hybrid approach can offer significant gains in computational efficiency over traditional RCs while simultaneously addressing some of the limitations of NGRCs. Our results suggest that hybrid RC-NGRC approach may be particularly beneficial in cases when computational efficiency is a high priority and an NGRC alone is not adequate.
description: 12 pages, 7 figures
Normal liver sparing by proton beam therapy for hepatocellular carcinoma: Comparison with helical intensity modulated radiotherapy and volumetric modulated arc therapy
Creators: name: Lim, Young Kyung
name: Kim, Tae Hyun
name: Park, Jung Hoon
name: Shin, Dong Ho
name: Kim, Sang Soo
name: Joo-Young Kim
name: Kim, Dae Yong
name: Joong-Won Park
name: Kim, Ja Young
name: Cho, Kwang Hyun
name: Choi, Sang Hyoun
name: Hojin Jeong
name: Kim, Dae Woong
name: Lee, Se Byeong
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Social Science
subject: Cell Biology
subject: Medicine
subject: Physics
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: Normal liver sparing by proton beam therapy for hepatocellular carcinoma: Comparison with helical intensity modulated radiotherapy and volumetric modulated arc therapy
Monte-Carlo dosimetry for intraoperative radiotherapy using a low energy x-ray source
Creators: name: Pradier, Olivier
name: Visvikis, Dimitris
name: Dounia Bouzid
name: Bert, Julien
name: Pierre-Francois Dupre
name: Benhalouche, Saadia
name: Boussion, Nicolas
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Mathematics
subject: FOS: Mathematics
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Biotechnology
subject: Cell Biology
subject: Medicine
subject: Physics
subject: Engineering
subject: Biophysics

description: Intraoperative radiotherapy (IORT) is continuously gaining ground in cancer treatment. However, there is currently no planning system associated with these devices, which precludes patient-specific dose delivery optimization. The objective of this study was the development and validation of a Monte Carlo simulation (MCS)-based dosimetry platform using the Intrabeam™ system.Methods. After surgical resection of the tumor this system delivers a single dose fraction at the surface of an applicator irradiating the tumor bed through a 50 kV x-ray beam. The GATE MCS platform was used in this study combining the phase space obtained by modeling the x-ray source and the detailed modeling of the additional parts of the Intrabeam™ system. The model was validated by comparing simulated versus experimental measurements of depth dose curves (DDC) and isotropy. A clinical validation study was also carried out using patient computed tomography images.Results. The mean deviation between measured and simulated DDC was 2.9% ± 4.4% and 5.9% ± 5.7% for the bare needle and the use of applicators, respectively. A good agreement with experimental measurements was also found in terms of dose isotropy with a maximum difference of 2.04% for the 40 mm diameter applicator. A patient study revealed a mean absolute deviation of 0.06 Gy between simulated and thermoluminescent dosimeters (TLD) measured skin doses.Conclusion. This study shows the potential of using the GATE MCS platform to model three-dimensional dose distributions of the Intrabeam™ system for use in IORT.
Validity of Norwegian Rectal Cancer Registry data at a major university hospital 1997–2005
Creators: name: Dahl, Olav
name: Sakkestad, Sunniva T.
name: Olsen, Bjørn C.
name: Karliczek, Anne
name: Pfeffer, Frank
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Hematology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry

description: Background. The Norwegian Rectal Cancer Registry (NRCR) has been used extensively to monitor patient treatment and outcomes since its establishment in 1993. Control of data validity is crucial to ensure reliable information, but an audit of the NRCR data validity has not been performed so far. This study aims to validate NRCR data on patients diagnosed in the period 1997–2005, Department of Surgery, Haukeland University Hospital.Material and methods. The material comprises NRCR data on all 482 patients diagnosed with rectal cancer in the period 1997–2005 at a major Norwegian university hospital. We checked 50 variables for discrepancies by comparing NRCR data with the medical records. All erroneous registrations were recorded.Results. One hundred patients (21%) had one or more data discrepancies in the registry, and 131 errors (0.5%) were noted in total. Sixteen variables (32%) had no erroneous registrations. Pre-operative CT and type of surgical procedure had the highest proportion of erroneous registrations (2.1%). Recorded errors were grouped into five variable categories: Pre-operative evaluation and adjuvant treatment (40 errors), surgical treatment (44 errors), pathological evaluation (20 errors), complications (7 errors) and oncological outcomes (20 errors). The majority of erroneous registrations (45%) were considered minor in severity, 27% were moderate and 28% were major.Conclusion. Assessment of the NRCR data from a nine-year period showed a good data validity in this hospital cohort.
MACHINE LEARNING FOR EARLY DETECTION AND PREVENTION OF CHRONIC DISEASES
Creators: name: Sachi, Savya
name: Afaque Alam
Publisher: name: Zenodo
Year: 2022

description: - In the field of biomedical and healthcare communities, accurate prediction plays a major role tofind out the patient's risk of the disease; the only way to overcome the mortality due to chronic diseases is topredict it earlier so that the disease prevention can be done; such a model is a patient's need in whichmachine learning is highly recommended; however, the precise prediction on the basis of symptomsbecomes too difficult for doctor. Technological development, including machine learning, has a huge impacton health through an effective analysis of various chronic diseases for more accurate diagnosis andsuccessful treatment. The hardest difficulty is accurately predicting sickness. Data mining is crucial inpredicting the sickness in order to solve this issue. Using a chronic illnesses dataset from the UCI machinelearning data warehouse, this work applies machine learning techniques to the analysis of chronic diseases.We employ data mining approaches to construct dependable prediction models for chronic illnesses, such asdiabetes, cancer, heart disease, and kidney disease.
description: - In the field of biomedical and healthcare communities, accurate prediction plays a major role tofind out the patient's risk of the disease; the only way to overcome the mortality due to chronic diseases is topredict it earlier so that the disease prevention can be done; such a model is a patient's need in whichmachine learning is highly recommended; however, the precise prediction on the basis of symptomsbecomes too difficult for doctor. Technological development, including machine learning, has a huge impacton health through an effective analysis of various chronic diseases for more accurate diagnosis andsuccessful treatment. The hardest difficulty is accurately predicting sickness. Data mining is crucial inpredicting the sickness in order to solve this issue. Using a chronic illnesses dataset from the UCI machinelearning data warehouse, this work applies machine learning techniques to the analysis of chronic diseases.We employ data mining approaches to construct dependable prediction models for chronic illnesses, such asdiabetes, cancer, heart disease, and kidney disease.
Predicting radiation-induced valvular heart damage
Creators: name: Cella, Laura
name: Oh, Jung Hun
name: Deasy, Joseph O.
name: Palma, Giuseppe
name: Liuzzi, Raffaele
name: Conson, Manuel
name: Picardi, Marco
name: Salvatore, Marco
name: Pacelli, Roberto
name: D'avino, Vittoria
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Earth and Environmental Sciences
Cell Biology
Medicine

description: Purpose. To develop a predictive multivariate normal tissue complication probability (NTCP) model for radiation-induced heart valvular damage (RVD). The influence of combined heart-lung irradiation on RVD development was included.Material and methods. Multivariate logistic regression modeling with the least absolute shrinkage and selection operator (LASSO) was used to build an NTCP model to predict RVD based on a cohort of 90 Hodgkin lymphoma patients treated with sequential chemo-radiation therapy. In addition to heart irradiation factors, clinical variables, along with left and right lung dose-volume histogram statistics, were included in the analysis. To avoid overfitting, 10-fold cross-validation (CV) was used for LASSO logistic regression modeling, with 50 reshuffled cycles. Model performance was assessed using the area under the receiver operating characteristic (ROC) curve (AUC) and Spearman's correlation coefficient (Rs).Results. At a median follow-up time of 55 months (range 12–92 months) after the end of radiation treatment, 27 of 90 patients (30%) manifested at least one kind of RVD (mild or moderate), with a higher incidence of left-sided valve defects (64%). Fourteen prognostic factors were frequently selected (more than 100/500 model fits) by LASSO, which included mainly heart and left lung dosimetric variables along with their volume variables. The averaged cross-validated performance was AUC-CV = 0.685 and Rs = 0.293. The overall performance of a final NTCP model for RVD obtained applying LASSO logistic regression to the full dataset was satisfactory (AUC = 0.84, Rs = 0.55, p < 0.001).Conclusion. LASSO proved to be an improved and flexible modeling method for variable selection. Applying LASSO, we showed, for the first time, the importance of jointly considering left lung irradiation and left lung volume size in the prediction of subclinical radiation-related heart disease resulting in RVD.
Is there a gender paradox in the association between conduct problems and cannabis use? A cohort-study among Swedish adolescents
Creators: name: Karlsson, P
name: Ekendahl, M
name: Raninen, Jonas
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 520101
subject: Child and adolescent development
classificationCode: 44
subject: Human society
classificationCode: 520502
subject: Gender psychology

description: Introduction: Conduct problems (CP) predict cannabis use prospectively but the research is mixed as to whether this association is stronger among girls. A stronger association among girls would suggest a ‘gender paradox’ as both CP and cannabis use is less common in this group. This study aimed to assess whether the longitudinal association between CP and cannabis use in Swedish adolescents is stronger among girls. Methods: Data from two waves of a nationally representative cohort study of Swedish adolescents born in 2001 were used. Baseline measurements were collected in 9th grade (at age 15–16) and follow-up measures at 11th grade (at age 17–18). Results: CP at baseline were significantly associated with cannabis use at follow-up adjusted for hyperactivity problems, emotional problems, socio-demographics, parental monitoring, school grades and truancy at baseline (odds ratio [OR] 1.14, 95% confidence interval [CI] 1.06–1.24) but not when also adjusting for substance use at baseline. Boys were more likely to have used cannabis during the past year, even when controlling for prior substance use (OR 2.29, 95% CI 1.76–2.98). The association between CP and cannabis use was significantly weaker for boys (OR 0.83, 95% CI 0.72–0.95 in the fully adjusted model). The predicted probability of cannabis use was stable at 0.13 for boys across levels of CP, but ranged from 0.05 to 0.16 for girls. Discussion and Conclusion: The longitudinal association between CP and cannabis use was stronger among girls. The findings are indicative of a ‘gender paradox’ in the association between CP and cannabis use.
Chitosan Composite Membrane with Efficient Hydroxide Ion Transport via Nano‐Confined Hydrogen Bonding Network for Alkaline Zinc‐Based Flow Batteries
Creators: name: Hu, Jing
name: Wang, Pengfei
name: Hu, Jianbo
name: Zheng, Menglian
name: Dong, Mingdong
Publisher: name: Zenodo
Year: 2024
Subjects: Chitosan
Membrane
Hydroxide Ion Transport
Alkaline Zinc-Based Flow Batteries

description: The development of membranes with rapid and selective ionic transport is imperative for diverse electrochemical energy conversion and storage systems, including fuel cells and flow batteries. However, the practical application of membranes is significantly hindered by their limited conductivity and stability under strong alkaline conditions. Herein, a unique composite membrane decorated with functional Cu2+ cross-linked chitosan (Cts-Cu-M) is reported and their high hydroxide ion conductivity and stability in alkaline flow batteries are demonstrated. The underlying hydroxide ions transport of the membrane through Cu2+ coordinated nano-confined channels with abundant hydrogen bonding network via Grotthuss (proton hopping) mechanism is proposed. Consequently, the Cts-Cu-M membrane achieves high hydroxide ion conductivity with an area resistance of 0.17 Ω cm2 and enables an alkaline zinc-based flow battery to operate at 320 mA cm−2, along with an energy efficiency of ≈80%. Furthermore, the membrane enables the battery for 200 cycles of long-cycle stability at a current density of 200 mA cm−2. This study offers an in-depth understanding of ion transport for the design and preparation of high-performance membranes for energy storage devices and beyond.
Experimental demonstration of improved reference-frame-independent quantum key distribution over 175km
Creators: name: Tian, Zhiyu
name: Xie, Ziran
name: Wang, Rong
name: Zhang, Chunmei
name: Sun, Shihai
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Reference-frame-independent (RFI) quantum key distribution (QKD) presents promising advantages, especially for mobile-platform-based implementations, as it eliminates the need for active reference frame calibration. While RFI-QKD has been explored in various studies, limitations in key rate and distance persist due to finite data collection. In this study, we experimentally demonstrate an improved RFI-QKD protocol proposed by Zhu \textit{et al.} [Opt. Lett. 47, 4219 (2022)], featuring a statistical quantity for bounding information leaked to Eve that exhibits more insensitivity to statistical fluctuations and more robustness to variations in the reference frame. Taking into account finite-size considerations and potential general attacks, RFI-QKD is implemented over a distance of 175 \si{\kilo\meter} in this work. We believe that our study extends the communication distance achievable by RFI-QKD, thereby constituting a notable advancement for its practical application.
description: 9 pages, 3 figures
Data and code related to the reverse engineering of WGDs in Angiosperms using an LRT framework based on a birth-death model
Creators: name: Tasdighian, Setareh
Publisher: name: Zenodo
Year: 2022

description: These are files include both the compiled code and the output files, associated with the model described in chapter four of my PhD thesis, to reverse engineer the location of WGDs on a phylogeny of angiosperms using an LRT framework built based on a previously published birth-death model. https://doi.org/10.1105/tpc.17.00313. The output files in this repository extends the results presented in the thesis, and contains new results for more gene families compared to the thesis.
description: These files will not be made publicly available and sharing will be made possible only by the approval of depositor of the original file.
Open Research: A Five-minute Guide
Creators: name: Quigley, Niamh
Publisher: name: Zenodo
Year: 2022
Subjects: open research
open access
open science
short guide

description: See blog post which includes these slides and transcript https://neevq.wordpress.com/2022/04/21/open-research-a-five-minute-guide/ A five-minute guide to open research, presented to participants of the Australian Library and Information Association (ALIA) Mentoring Scheme as part of a 'Research and Publishing' webinar on 21 April 2022. For more information about ALIA's Mentoring Scheme, see https://www.alia.org.au/Web/Careers/Professional-Development/Mentoring/Web/Careers/ALIA-Mentoring-Scheme.aspx
Język współczesnej emigracji Polaków. Kilka pierwszych uwag
Creators: name: Jura, Marcin
name: Zarzeczny, Grzegorz
Publisher: name: Zenodo
Year: 2007
Subjects: Polish language
Scotland
Ireland
econimical emigration

description: The following paper constitutes only a part of the work devoted to the language of modern economical emigration in Scotland and Ireland – the novelty of this phenomenon resulted in its lack in the current researches. The first part presents some terminological assumptions and the social context. The second part constitutes both the juxtaposition of Elżbieta Sękowska’s (year 1994) and the contemporary’s research results. On the ground of discussed material some conclusions were drawn in the last part of the article.
description: {"references": ["Anusiewicz J. (1994), Lingwistyka kulturowa. Zarys problematyki, Wroc\u0142aw.", "Dubisz S. (1997), J\u0119zyk polski poza granicami kraju \u2013 wst\u0119pne informacje i definicje, [w:] Dubisz S. (red.), J\u0119zyk polski poza granicami kraju, Opole.", "Jura M., G. Zarzeczny (2007), S\u0142ownictwo wsp\u00f3\u0142czesnej emigracji ekonomicznej (Szkocja i Irlandia), referat wyg\u0142oszony podczas konferencji J\u0119zyk a socjum. Funkcjonowanie j\u0119zyka w przestrzeni spo\u0142ecznej, Toru\u0144 15-16 III 2007 r.", "Kubiak H. (1976), Om\u00f3wienie dyskusji, [w:] Kubiak H., A. Pilch (red.), Stan i potrzeby bada\u0144 nad zbiorowo\u015bciami polonijnymi, Wroc\u0142aw.", "Lewi\u0144ski P.H. (2000), O osobliwo\u015bciach j\u0119zyka chicagowskiego, [w:] Mazur J. (red.), S\u0142ownictwo wsp\u00f3\u0142czesnej polszczyzny w okresie przemian, Lublin.", "Miodunka W. (1980), Teoria p\u00f3l j\u0119zykowych. Spo\u0142eczne i indywidualne ich uwarunkowania, Warszawa.", "O\u017c\u00f3g K. (2006), S\u0142owo wst\u0119pne, [w:] O\u017c\u00f3g K., E. Oronowicz-Kida (red.), Przemiany j\u0119zyka na tle przemian wsp\u00f3\u0142czesnej kultury, Rzesz\u00f3w.", "Paluch A.K. (1976), Inkluzywne i ekskluzywne rozumienie terminu \"Polonia\", [w:] Kubiak H., A. Pilch (red.), Stan i potrzeby bada\u0144 nad zbiorowo\u015bciami polonijnymi, Wroc\u0142aw.", "Radkiewicz A. (2006), Emigracja zarobkowa Polak\u00f3w do Irlandii. Raport z bada\u0144, Warszawa.", "S\u0119kowska E. (1994), J\u0119zyk zbiorowo\u015bci polonijnych w krajach angloj\u0119zycznych. Zagadnienia leksykalno-s\u0142owotw\u00f3rcze, Warszawa"]}
title: Catalogus Realis. VI. Historische Hilfswissenschaften. VIc : Reisen
Creators: name: Philipps-Universität Marburg
Publisher: name: Philipps-Universität Marburg
Year: 2020
Subjects: Hassiaca
Systematischer Katalog
Library and information sciences
Bibliotheks- und Informationswissenschaft

description: Elektronische Reproduktion von: Catalogus Realis. VI. Historische Hilfswissenschaften. VIc : Reisen. - Stand: Dezember 2019. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: Sonderlesesaal. - Bemerkungen: Der Katalog verzeichnet in systematisch-sachlicher Ordnung den Bestand der Universitätsbibliothek Marburg von den Anfängen bis 1957. Später erworbene ältere Literatur ist hier nicht verzeichnet. Mit Hilfe dieses Katalogs ist die Suche nach Literatur zu bestimmten Inhalten und Themen möglich. – Zur Systematik: Die Signaturen der einzelnen Bücher und Zeitschriften geben die Ordnung des Bestands wieder. Alle Signaturen beginnen mit einer römischen Zahl von I (1) bis XX (20), die das jeweilige Fach (Theologie, Geschichte, Medizin usw.) bezeichnet. Die weitere Untergliederung ergibt sich aus den nachfolgenden Kleinbuchstaben und arabischen Zahlen. Beispiel: XVIa A 117. Die Großbuchstaben A, B und C sind nicht Teil der Systematik, sondern bezeichnen das Format der betreffenden Bände: A = Folio (großformatige Bände), B = Quart (mittelgroße Bände), C = Oktav (kleinformatige Bände). - Digitalisiert 2020
description: I. Allgemeines über Reisen. 80 - 8° (594 – 666.) 80 70 - 4° (145 – 164.) 24 - fol. (80 – 81.) 13 II. Reisen in Deutschland 145 - 8° (667 – 699.) 145 - 4° (165m.) 42 III. Reisen in Europa. 165 - Schweiz, Alpen, Italien, Frankreich, Spanien, Portugal 165 - - 8° (701 – 806.) 165 - - 4° (168o – 175am.) 44 - - fol. (83.) 13 - England, Belgien u. Holland, Nordische Staaten (Dänemark, Norwegen, Island Schweden) 235 - - 8° (810 – 847.) 233 - - 4° (175 – 177.) 46 - Russland, Polen, Türkei, Griechenland 264 - - 8° (851 – 863.) 264 254 - - 4° (178. ) 50 - - fol. (83 – 84.) 13 IV. Aussereuropäische Reisen. 287 - Levante u. Kleinasien, Dalmatien, Orient, Kaukasus, Palaestina, Arabien 284 274 - - 8° (863cg – 882.) 281 - - 4° (178 - 184.) 50 - - fol. (86 – 89.) 14 - Asien (Persien, Kaukasusländer, Sibirien u. Uralaltai, Japan, China, Indien etc.) 315 - - 8° (883 – 904.) 312 - - 4° (184 – 185.) 59 - - fol. (89b – 91.) 18 - Afrika 350 340 - - 8° (906 – 927.) 350 - - 4° (188 – 194t.) 60 - Amerika (auch Arktis u. Antarktis) 390 380 - - 8° (933 – 970.) 390 - - 4° (194g – 195u.) 70 - Australien u. Polynesien. Südpol 458 - - 8° (967 – 970.) 452 447 - - 4° (195tg – 195v.) 74
Modelling inhibition of avian aromatase by azole pesticides
Creators: name: A.K. Saxena
name: J. Devillers
name: S.S. Bhunia
name: E. Bro
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Evolutionary Biology
subject: Genetics
subject: Biochemistry

description: The potential effects of pesticides and their metabolites on the endocrine system are of major concern to wildlife and human health. In this context, the azole pesticides have earned special attention due to their cytochrome P450 aromatase inhibition potential. Cytochrome P450 aromatase (CYP19) catalyses the conversion of androstenedione and testosterone into oestrone and oestradiol, respectively. Thus, aromatase modulates the oestrogenic balance essential not only for females, but also for male physiology, including gonadal function. Its inhibition affects reproductive organs, fertility and sexual behaviour in humans and wildlife species. Several studies have shown that azole pesticides are able to inhibit human and fish aromatases but the information on birds is lacking. Consequently, it appeared to be of interest to estimate the aromatase inhibition of azoles in three different avian species, namely Gallus gallus, Coturnix coturnix japonica and Taeniopygia guttata. In the absence of the crystal structure of the aromatase enzyme in these bird species, homology models for the individual avian species were constructed using the crystal structure of human aromatase (hAr) (pdb: 3EQM) that showed high sequence similarity for G. gallus (82.0%), T. guttata (81.9%) and C. japonica (81.2%). A homology model with Oncorhynchus mykiss (81.9%) was also designed for comparison purpose. The homology-modelled aromatase for each avian and fish species and crystal structure of human aromatase were selected for docking 46 structurally diverse azoles and related compounds. We showed that the docking behaviour of the chemicals on the different aromatases was broadly the same. We also demonstrated that there was an acceptable level of correlation between the binding score values and the available aromatase inhibition data. This means that the homology models derived on bird and fish species can be used to approximate the potential inhibitory effects of azoles on their aromatase.
Biochemical characteristics of Trichoderma atroviride associated with conidium fitness for biological control
Creators: name: Daryaei, Amir
name: E. Eirian Jones
name: Alizadeh, Hossein
name: Glare, Travis R.
name: Falloon, Richard E.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Cell Biology
subject: Microbiology
subject: Biochemistry

description: ABSTRACTEffects of abiotic factors during production (temperature, nutrients, water activity, pH) on conidium fitness (quantity and quality) of Trichoderma atroviride LU132 (a key biocontrol agent) were studied. Conidia from the culturing regimes which resulted in greatest and least bioactivity against Rhizoctonia solani in dual culture assays were selected to assess effects of storage conditions on conidial fitness over time. Further studies assessed interaction effects of temperatures (20°C or 30°C) and sugars (dextrose or sucrose) on conidium germination and bioactivity as fresh conidia, or after 6 months of storage. Biochemical analyses of sugars and fatty acids were carried out to determine relationships between quality variations and cellular characteristics for conidia produced in different culturing conditions. Low trehalose content in conidia (e.g. at 20°C) was associated with the least conidium fitness, although high trehalose content did not necessarily support conidium fitness. High proportions of total fatty acids in conidia were mostly associated with the least conidium fitness. When Trichoderma was grown at high carbon to nitrogen ratio (e.g. at C:N 160:1), the total conidium fatty acids content increased. This study also indicated that the monosaccharide dextrose is metabolically optimal for T. atroviride LU132 at 20°C while the disaccharide sucrose is optimal at 30°C. These studies indicate that physical growth conditions and nutritional requirements attribute in conidium fitness of T. atroviride LU132, and provide important knowledge supporting optimum production of biocontrol agents based on T. atroviride, and possibly other similar biocontrol agents.
News diets, social media use and non-institutional participation in three communication ecologies: comparing Germany, Italy and the UK
Creators: name: Mosca, Lorenzo
name: Quaranta, Mario
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology

description: ABSTRACTIn the course of a three-year research project comparing social media and political participation across the European Union, we collected data on representative samples of internet users from Germany, Italy and the UK. Online users were surveyed just after the May 2014 European elections. The three countries have been selected as they differ not only in terms of institutional features but also in terms of the character of their media systems: ‘liberal’ in the UK, ‘democratic-corporatist’ in Germany and ‘polarized pluralist’ in Italy. Although previous studies have not put into direct relationship media systems with participatory patterns, we hypothesized that different types of media ecologies may generate peculiar incentives for non-institutional participation. Taking such differences into account, our paper sheds light on the linkage between digital media and unconventional participation across the three countries. Our hypothesis is that distinct news diets and different social media platforms may influence non-institutional participation in specific ways that reflect varying contextual characteristics. We assess the role of different news diets on unconventional participation, distinguishing our respondents according to their main sources of information (occasional, traditional univores, digital univores and omnivores). We then consider the association between the use of different social media (i.e. Facebook and Twitter) and non-institutional participation. Finally, we take into account the indirect effect of national contexts by running interaction models. Our findings show that news diets and social media use matter in the three countries, but that substantial differences are hard to find across them.
Tidal Love numbers and approximate universal relations for fermion soliton stars
Creators: name: Berti, Emanuele
name: De Luca, Valerio
name: Del Grosso, Loris
name: Pani, Paolo
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Fermion soliton stars are a consistent model of exotic compact objects which involve a nonlinear interaction between a real scalar field and fermions through a Yukawa term. This interaction results in an effective fermion mass that depends upon the vacuum structure in the scalar potential. In this work we investigate the tidal deformations of fermion soliton stars and compute the corresponding tidal Love numbers for different model parameters. Furthermore, we discuss the existence of approximate universal relations for the electric and magnetic tidal deformabilities of these stars, and compare them with other solutions of general relativity, such as neutron stars or boson stars. These relations for fermion soliton stars are less universal than for neutron stars, but they are sufficiently different from the ordinary neutron star case that a measurement of the electric and magnetic tidal Love numbers (as potentially achievable by next-generation gravitational wave detectors) can be used to disentangle these families of compact objects. Finally, we discuss the conditions for tidal disruption of fermion soliton stars in a binary system and estimate the detectability of the electromagnetic signal associated with such tidal disruption events.
description: 15 pages, 4 figures. v2: new figure added, matches version accepted in PRD
Optimal Allocation of Irrigation Water for Rice Production in Ghana, Case Study: Kpong Irrigation Project (KIP)
Creators: name: Otoo, Joseph
name: Ofori, Johnson K.
name: Cephas Bosrotsi
Publisher: name: figshare
Year: 2015
Subjects: Uncategorized

description: This paper dealt with the formulation of Linear Programming Model for optimal allocation of irrigation water for rice production.
Monotone ODE with Discontinuous Vector Fields in Sequence Spaces
Creators: name: Zubelevich, Oleg
Publisher: name: Zenodo
Year: 2022
Subjects: Infinite-dimensional evolution equations, infinite-order system of ODEs, countable system of ODEs

description: We consider a system of ODE in a Fr\'echet space with unconditional Schauder basis. The right side of the ODE is a discontinuous function. Under certain monotonicity conditions we prove an existence theorem for the corresponding initial value problem.
description: 58D25, 46A04, 46A45, 47H07, 47J35, 34G20
INFLUÊNCIA DA TRAQUEOSTOMIA PRECOCE EM PACIENTES NEUROLÓGICOS EM VENTILAÇÃO MECÂNICA
Creators: name: Dayane Borges MELO
name: Marcelo MAZETTO
name: Patrícia de Assis ANDRADE
name: Fabiana Oliveira FERREIRA
name: Regina HORLANYS
name: Gabriela Meira Nóbrega dos Santos GOMES
name: Aline Brito PIMENTEL
Publisher: name: Zenodo
Year: 2024
Subjects: Traqueostomia
Lesões encefálicas traumáticas
Neurologia

description: RESUMO

Introdução: A traqueostomia é um dos procedimentos cirúrgicos mais antigos e mais comumente realizados em pacientes críticos nas UTIs. É indicado com objetivo de aliviar obstruções de vias aéreas superiores, oferecer suporte ventilatório prolongado, dentre outros benefícios. Objetivo: Abordar e atualizar os conhecimentos com relação às indicações e o tempo de realização de traqueostomia. Metodologia: Trata-se de uma revisão integrativa de literatura relacionada com relação às indicações e o tempo de realização de traqueostomia em pacientes neurológicos. Foram incluídos artigos dentre o período de 2017 a 2022 nos idiomas inglês e português, também foram selecionados artigos que respondessem à pergunta norteadora. Resultados e discussão: Ao comparar a traqueostomia tardia e a traqueostomia precoce foi observado um risco significativamente menor de mortalidade hospitalar no grupo de traqueostomia precoce e menor tempo médio de permanência na UTI e duração média da ventilação mecânica. Contudo, é possível mencionar as complicações associadas as traqueostomias tais como reintubações ou infecções relacionadas à assistência em saúde, são fatores de internação potencialmente modificáveis que têm uma associação mais forte com a traqueostomia do que as características da internação. Conclusão: É possível observar que a traqueostomia precoce é extremamente vantajosa para pacientes neurológicos com traumatismo cranioencefálico, tendo em vista que há diminuição no tempo necessário de ventilação mecânica, diminuição no tempo de UTI, menor taxa de pneumonia, melhor desmame do ventilador, menor tempo no uso de antibióticos, menor tempo de internação, menores taxas de complicações, redução da necessidade de sedação e diminuição da mortalidade.
Evaluation of nutritive values of papua foxtail millet (Setaria italica sp) and its substitutive effect for yellow corn on broiler performances
Creators: name: Iqbal, Zahid
Publisher: name: figshare
Year: 2015
Subjects: subject: Soil Science
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Engineering
subject: Genetics
subject: Education

description: Yellow corn is still an expensive and one of imported feedstuffs used by feed manufacturing in Indonesia.
Research on the use of inconventional feed for broiler is currently elaborated in particular interest on Papua
foxtail millet (Setaria italica sp) of yellow variety. The aims were to analyze proximate, fibre, calcium,
phosphorus, β-carotene, tannin, phytic acid and amino acids contents, and examine the possibility of partly
substitution of yellow corn with Papua Foxtail millet. The results showed that Papua foxtail millet contained
higher protein than yellow corn (12.07 vs 8.7%) and high estimated metabolizable energy 2941 kcal/kg. it also
rich in methionine and lysine with reasonable amount of other essential amino acids. The biological experiment
was designed to evaluate substitutive effect Papua foxtail millet to yellow corn. Two hundred and fifty day old
chicks of Lohmann broiler were used. They were allotted to 5 dietary treatments, namely P0 = basal feed (without
Papua foxtail millet), P1 = basal feed in which 2.5% of yellow corn was substituted by Papua foxtail millet, P2 =
basal feed in which 5.0% of yellow corn was substituted by Papua foxtail millet, P3 = basal feed in which 7.5% of
yellow corn was substituted by Papua foxtail millet, P4 = basal feed in which 10.0% of yellow corn was substituted
by Papua foxtail millet. Feed and water were provided ad libitum. The results showed that beside contain high
phytic acid Papua foxtail millet shows a potential use for poultry feedstuffs and utilization of 10% Papua foxtail
Millet as substitute of corn showed no adverse effect on broiler performances, even increase carcass percentage.
The Ca II K index-Mg II index relation: A Hilbert-Huang Transform approach
Creators: name: Reda, Raffaele
name: Penza, Valentina
Publisher: name: arXiv
Year: 2024
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The solar activity, which is driven by a variable magnetic field, exhibits changes along several time scales, the 11-year being the most known. In addition to the SunSpot Number, the Ca II K index and the Mg II index are indices widely employed among those proposed to quantify the solar activity, also because of their ability to trace the solar UV emission. In this work, we compare the Ca II K 0.1nm emission index to the Mg II index over the time interval 1978-2017, which covers almost four solar cycles. We show that they are strongly correlated across each solar cycle (r$\geq$0.94), providing the corresponding linear regression fit parameters. The Hilbert-Huang Transform is then used to decompose such indices into their intrinsic mode of oscillation. By studying how their components are correlated over the different time scales, it is found that the maximum correlation is observed at the 11-year scale, while the correlation is less strong going to smaller time scales.
A Two-Level Stochastic Model for the Lateral Movement of Vehicles Within Their Lane Under Homogeneous Traffic Conditions
Creators: name: Neis, Nicole
name: Beyerer, Juergen
Publisher: name: arXiv
Year: 2024
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: The lateral position of vehicles within their lane is a decisive factor for the range of vision of vehicle sensors. This, in turn, is crucial for a vehicle's ability to perceive its environment and gain a high situational awareness by processing the collected information. When aiming for increasing levels of vehicle autonomy, this situational awareness becomes more and more important. Thus, when validating an autonomous driving function the representativeness of the submicroscopic behavior such as the lateral offset has to be ensured. With simulations being an essential part of the validation of autonomous driving functions, models describing these phenomena are required. Possible applications are the enhancement of microscopic traffic simulations and the maneuver-based approach for scenario-based testing. This paper presents a two-level stochastic approach to model the lateral movement of vehicles within their lane during road-following maneuvers under homogeneous traffic conditions. A Markov model generates the coarse lateral offset profile. It is superposed with a noise model for the fine movements. Both models are set up using real-world data. The evaluation of the model shows promising qualitative and quantitative results, the potential for enhancements and extreme low computation times (10000 times faster than real time).
description: 8 pages, 12 figures