cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
One-Year Safety of Olodaterol Once Daily via Respimat® in Patients with GOLD 2–4 Chronic Obstructive Pulmonary Disease: Results of a Pre-Specified Pooled Analysis
Creators: name: Lorcan McGarvey
name: Niewoehner, Dennis
name: Magder, Sheldon
name: Sachs, Paul
name: Tetzlaff, Kay
name: Hamilton, Alan
name: Korducki, Lawrence
name: Bothner, Ulrich
name: Vogelmeier, Claus
name: Koch, Andrea
name: Ferguson, Gary T.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Cancer
subject: Immunology
subject: FOS: Clinical medicine
subject: Pharmacology
subject: Cell Biology
subject: Medicine

description: The novel long-acting β2-agonist olodaterol demonstrated an acceptable safety profile in short-term phase II clinical studies. This analysis of four randomized, double-blind, placebo-controlled, parallel-group, phase III studies (1222.11, NCT00782210; 1222.12, NCT00782509; 1222.13, NCT00793624; 1222.14, NCT00796653) evaluated the long-term safety of olodaterol once daily (QD) in a large cohort of patients with moderate to very severe (Global initiative for chronic Obstructive Lung Disease 2–4) chronic obstructive pulmonary disease (COPD). The studies compared olodaterol (5 or 10 μg) QD via Respimat®, formoterol 12 μg twice daily (BID) via Aerolizer® (1222.13 and 1222.14), and placebo for 48 weeks. Patients continued receiving background maintenance therapy, with ∼60% receiving concomitant cardiovascular therapy and 25% having a history of concomitant cardiac disease. Pre-specified analyses of pooled data assessed the adverse events (AEs) and serious AEs in the whole population, and in subgroups with cardiac disease, along with in-depth electrocardiogram and Holter monitoring. In total, 3104 patients were included in the safety analysis: 876 received olodaterol 5 μg, 883 received olodaterol 10 μg, 885 received placebos, and 460 received formoterol 12 μg BID. Overall incidence of on-treatment AEs (71.2%), serious AEs (16.1%), and deaths (1.7%) were balanced across treatment groups. Respiratory and cardiovascular AEs, including major adverse cardiac events, were reported at similar frequencies in placebo and active treatment groups. The safety profiles of both olodaterol 5 μg (marketed and registered dose) and 10 μg QD delivered via Respimat® are comparable to placebo and formoterol BID in this population, with no safety signals identified.
Congruence subgroups and crystallographic quotients of small Coxeter groups
Creators: name: Kumar, Pravin
name: Naik, Tushar Kanta
name: Singh, Mahender
Publisher: name: arXiv
Year: 2022
Subjects: subject: Group Theory (math.GR)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 20F55, 20H15 (Primary), 20F36 (Secondary)

description: Small Coxeter groups are precisely the ones for which the Tits representation is integral, which makes the study of their congruence subgroups relevant. The symmetric group $S_n$ has three natural extensions, namely, the braid group $B_n$, the twin group $T_n$ and the triplet group $L_n$. The latter two groups are small Coxeter groups, and play the role of braid groups under the Alexander-Markov correspondence for appropriate knot theories, with their pure subgroups admitting suitable hyperplane arrangements as Eilenberg-MacLane spaces. In this paper, we prove that the congruence subgroup property fails for infinite small Coxeter groups which are not virtually abelian. As an application, we deduce that the congruence subgroup property fails for both $T_n$ and $L_n$ when $n \ge 4$. We also determine subquotients of principal congruence subgroups of $T_n$, and identify the pure twin group $PT_n$ and the pure triplet group $PL_n$ with suitable principal congruence subgroups. Further, we investigate crystallographic quotients of these two families of small Coxeter groups, and prove that $T_n /PT_n^{'}$, $T_n/T_n^{''}$ and $L_n /PL_n^{'}$ are crystallographic groups. We also determine crystallographic dimensions of these groups and identify the holonomy representation of $T_n/T_n^{''}$.
description: 25 pages, to appear in Forum Mathematicum
Universal Mechanism for Quantitative Understanding of Global Ozone Depletion
Creators: name: Lu, Qing-Bin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: This paper formulates the cosmic-ray(CR)-driven electron-induced reaction (CRE) mechanism to provide a quantitative understanding of global ozone depletion. Based on a proposed electrostatic bonding mechanism for charged-induced adsorption of molecules on surfaces and on the measured dissociative electron transfer (DET) cross sections of ozone depletion substances (ODSs) adsorbed on ice, an analytical equation is derived to give atmospheric chlorine atom concentration: $$[Cl] = \sum_i k^i θ_{ODS}^i Φ_e^2,$$ where $Φ_e$ is the CR-produced prehydrated electron ($e_{pre}^-$) flux on atmospheric particle surfaces, $θ_{ODS}^i$ is the surface coverage of an ODS, and $k^i$ is the ODS's effective DET coefficient comprising the DET cross section, lifetimes of surface-trapped $e_{pre}^-$ and Cl$^-$, and particle surface area density. With concentrations of ODSs as the sole variable, our calculated results of time-series ozone depletion rates in global regions in the 1960s, 1980s and 2000s show generally good agreement with observations, particularly with ground-based ozonesonde data and satellite-measured data over Antarctica and with satellite data in the tropics in a narrow altitude band at 13-20 km. Good agreements with satellite data in the Arctic and midlatitudes are also found. A new insight into the denitrification effect on ozone loss is given quantitatively. But this equation overestimates tropospheric ozone loss at northern midlatitudes and the Arctic, likely due to increased ozone production by the halogen chemistry in polluted regions. Finally, ozone maps from ozonesonde data clearly reveal the scope of the tropical ozone hole. The results render confidence in applying the CRE equation to achieve a quantitative understanding of global ozone depletion.
description: 30 pages, 5 figures
Alburnoides damghani Jouladeh-Roudbar, Eagderi, Esmaeili, Coad & Bogutskaya 2016
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Alburnoides
Alburnoides damghani

description: 170. Alburnoides damghani Jouladeh-Roudbar, Eagderi, Esmaeili, Coad & Bogutskaya, 2016
Common name. Damghan spirlin-Damghan riffle minnow
Taxonomy. Original description: Alburnoides damghani Jouladeh-Roudbar, Eagderi, Esmaeili, Coad & Bogutskaya, 2016: 165, figs. 3-6 [Cheshmeh Ali, Damghan River tributary, near Damghan City, Dasht-e Kavir basin, Semnan Province, Iran, 36°16'45.6"N, 54°05'01.6"E, elevation 1569 meters; holotype: CMNFI 2015-0091].
Revisions. None.
Illustrations: Jouladeh-Roudbar et al. (2016: 165, fig. 3).
Distribution in Iran. —Distribution in River Basin: Dasht-e Kavir.—Distribution in Ecoregions: 448-Kavir & Lut Deserts.
Status in Iran. [Endemic].—Khayateh-e Damghan.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018); Jouladeh-Roudbar et al. (2020) and Eagderi et al. (2022).—Iran material: ZM-CBSU.
Conservation. —IUCN: NE.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 56, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
Topological 4D gravity and gravitational defects
Creators: name: Boujakhrout, Y.
name: Sammani, R.
name: Saidi, E. H
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Using the Chern-Simons formulation of AdS3 gravity as well as the Costello-Witten-Yamazaki (CWY) theory for quantum integrability, we construct a novel topological 4D gravity given by Eq(5.1) with observables based on gravitational gauge field holonomies. The field action $S^{grav}_{4D}$ of this gravity has a gauge symmetry $SL(2,\mathbb{C})$ and reads also as the difference $S^{CWY_{L}}_{4D}-S^{CWY_{R}}_{4D}$ with 4D Chern-Simons field actions $S^{CWY_{L/R}}_{4D}$ given by left/right CWY theory Eq(3.9). We also use this 4D gravity derivation to build observables describing gravitational topological defects and their interactions. We conclude our study with few comments regarding quantum integrability and the extension of AdS$_{3}$/CFT$_{2}$ correspondence with regard to the obtained topological 4D gravity.
Flow-induced focal adhesion remodeling mediated by local cytoskeletal stresses and reorganization
Creators: name: Verma, Deepika
name: Fanjie Meng
name: Sachs, Frederick
name: Hua, Susan Z.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: Biological Sciences
subject: Biotechnology
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cell Biology
subject: Physics
subject: Biophysics

description: Cells respond to fluid shear stress through dynamic processes involving changes in actomyosin and other cytoskeletal stresses, remodeling of cell adhesions, and cytoskeleton reorganization. In this study we simultaneously measured focal adhesion dynamics and cytoskeletal stress and reorganization in MDCK cells under fluid shear stress. The measurements used co-expression of fluorescently labeled paxillin and force sensitive FRET probes of α-actinin. A shear stress of 0.74 dyn/cm2 for 3 hours caused redistribution of cytoskeletal tension and significant focal adhesion remodeling. The fate of focal adhesions is determined by the stress state and stability of the linked actin stress fibers. In the interior of the cell, the mature focal adhesions disassembled within 35–40 min under flow and stress fibers disintegrated. Near the cell periphery, the focal adhesions anchoring the stress fibers perpendicular to the cell periphery disassembled, while focal adhesions associated with peripheral fibers sustained. The diminishing focal adhesions are coupled with local cytoskeletal stress release and actin stress fiber disassembly whereas sustaining peripheral focal adhesions are coupled with an increase in stress and enhancement of actin bundles. The results show that flow induced formation of peripheral actin bundles provides a favorable environment for focal adhesion remodeling along the cell periphery. Under such condition, new FAs were observed along the cell edge under flow. Our results suggest that the remodeling of FAs in epithelial cells under flow is orchestrated by actin cytoskeletal stress redistribution and structural reorganization.
Typhlodrominae Wainstein
Creators: name: ZahidiK, Abdelaziz
name: Akchour, Abdellah
name: K, Serge Kreiter
name: TixierK, Marie-Stéphane
name: MsandaK, Fouad
name: MousadikK, Abdelhamid El
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Phytoseiidae

description: Subfamily Typhlodrominae Wainstein  Typhlodromini Wainstein 1962: 26.
description: Published as part of ZahidiK, Abdelaziz, Akchour, Abdellah, K, Serge Kreiter, TixierK, Marie-Stéphane, MsandaK, Fouad & MousadikK, Abdelhamid El, 2023, Phytoseiid mites (Acari: Mesostigmata) from Central West Morocco: new records and key to females of all recorded Moroccan species, pp. 691-724 in Acarologia 63 (3) on page 705, DOI: 10.24349/v5of-5oe1, http://zenodo.org/record/10786247
Role of Mitogen-Activated Protein (MAP) Kinase Pathways in Metabolic Diseases
Creators: name: Ng, Gavin Yong Quan
name: Loh, Zachary Wai-Loon
name: Fann, David Y
name: Mallilankaraman, Karthik
name: Arumugam, Thiruma
name: Hande, M Prakash
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3205
subject: Medical biochemistry and metabolomics

description: Physiological processes that govern the normal functioning of mammalian cells are regulated by a myriad of signalling pathways. Mammalian mitogen-activated protein (MAP) kinases constitute one of the major signalling arms and have been broadly classified into four groups that include extracellular signal-regulated protein kinase (ERK), c-Jun N-terminal kinase (JNK), p38, and ERK5. Each signalling cascade is governed by a wide array of external and cellular stimuli, which play a critical part in mammalian cells in the regulation of various key responses, such as mitogenic growth, differentiation, stress responses, as well as inflammation. This evolutionarily conserved MAP kinase signalling arm is also important for metabolic maintenance, which is tightly coordinated via complicated mechanisms that include the intricate interaction of scaffold proteins, recognition through cognate motifs, action of phosphatases, distinct subcellular localisation, and even post-translational modifications. Aberration in the signalling pathway itself or their regulation has been implicated in the disruption of metabolic homeostasis, which provides a pathophysiological foundation in the development of metabolic syndrome. Metabolic syndrome is an umbrella term that usually includes a group of closely associated metabolic diseases such as hyperglycaemia, hyperlipidaemia, and hypertension. These risk factors exacerbate the development of obesity, diabetes, atherosclerosis, cardiovascular diseases, and hepatic diseases, which have accounted for an increase in the worldwide morbidity and mortality rate. This review aims to summarise recent findings that have implicated MAP kinase signalling in the development of metabolic diseases, highlighting the potential therapeutic targets of this pathway to be investigated further for the attenuation of these diseases.
Investigating the neutron star physics through observations of several young pulsars in the dipole-field re-emergence scenario
Creators: name: Yan, Yu-Long
name: Cheng, Quan
name: Zheng, Xiao-Ping
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The observed timing data, magnetic tilt angle $χ$, and age of young pulsars could be used to probe some important issues about neutron star (NS) physics, e.g., the NS internal magnetic field configuration, and the number of precession cycles $ξ$. \textbf{Both} quantities are critical in studying the continuous gravitational wave emission from pulsars, and the latter generally characterizes the mutual interactions between superfluid neutrons and other particles in the NS interior. The timing behavior of pulsars can be influenced by the dipole field evolution, which instead of decaying, may increase with time. An increase in the dipole field may result from the re-emergence of the initial dipole field $B_{\rm d,i}$ that was buried into the NS interior shortly after the birth of the NS. In this work, the field re-emergence scenario $ξ$ and the internal field configuration of several young pulsars, as well as their $B_{\rm d, i}$ are investigated by assuming typical accreted masses $ΔM$. Moreover, since the Crab pulsar has an exactly known age and its tilt angle change rate can be inferred from observations, we can set stringent constraints on its $ξ$, $B_{\rm d,i}$, and $ΔM$. Although for other young pulsars without exactly known ages and tilt angle change rates, these quantities cannot be accurately determined, we find that their $ξ$ are generally within $\sim10^4-10^6$, and some of them probably have magnetar-strength $B_{\rm d,i}$. Our work could be important for investigating the transient emissions associated with NSs, the origin of strong magnetic fields of NSs, pulsar population, continuous gravitational wave emission from pulsars, and accretion under extreme conditions in principle.
Alburnoides eichwaldii
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Alburnoides
Alburnoides eichwaldii

description: 171. Alburnoides eichwaldii (De Filippi, 1863)
Common name: Kura chub
Taxonomy: Original description: Alburnus eichwaldii DeFilippi 1863: 392 [Kura River near Tiflis [T'bilisi], Georgia, Eurasia; syntypes: MZUT 677 (4), NMW 55516 (2)].
Revisions. None.
Illustrations. Jouladeh-Roudbar et al. (2020: 114, fig. 201).
Distribution in Iran. —Distribution in River Basin: Caspian Sea.—Distribution in Ecoregions: 434-Kura-South Caspian Drainages.
Status in Iran. [Native].—Khayateh-e Aras.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018); Jouladeh-Roudbar et al. (2020) and Eagderi et al. (2022).—Iran material: ZM-CBSU.
Conservation. —IUCN: LC.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 56, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
Design and Scaleup of Micellar-Polymer Flooding in the Presence of Heterogeneity
Creators: name: Shook, George Michael
Publisher: name: The University of Texas at Austin
Year: 1988
Subjects: Polymer flooding
Permeable media

description: A three dimensional, multiphase, multicomponent micellar-polymer simulator has been used to identify the most important scaling groups and design parameters in heterogeneous permeable media. This was done in a series of sensitivity studies where a single process design parameter was varied, holding all others constant. In this way the influence of each variable has been well established. The studies were conducted on two different reservoir types, both of which are of particular interest in chemical flooding. The variables studied include, among others, mobility ratio, gravity, transverse and longitudinal dispersion, capillary trapping forces, and salinity gradient design. A modified cation exchange formulation has also been presented. In addition to correcting an inconsistency in the governing equations, the side benefit of removing an iteration loop from the simulator is described. Finally, several gravity formulations are compared under conditions of segregated flow.
A Study of the Effects of Heterogeneities on Immiscible Displacements and Their Representation in Numerical Simulators
Creators: name: Waggoner, John Raymond
Publisher: name: The University of Texas at Austin
Year: 1985
Subjects: Immiscible displacement
Reservoir characterization

description: Reservoir characterization is the process of discretizing the continuous geologic description of a reservoir into grid blocks for input into a numerical reservoir simulator. The accuracy of this discretization process is of great importance since the simulation results are often used to make important and expensive decisions. This thesis looks at the effects of some common permeability heterogeneities, namely systematically graded permeability and cross bedding, which occur in common geologic depositional units such as channel sands and barrier bar sands. After this qualitative discussion of the effects of flow rate, permeability contrast, viscosity ratio, and cross bedding on water saturation profiles in heterogeneous porous media, this study examines the use of pseudo functions, such as pseudo fractional flow, to represent the heterogeneity in a one dimensional, homogeneous reservoir. Three analytical methods of calculating pseudo fractional flow, Dykstra-Parsons, Hearn, and Vertical Equilibrium, are compared to simulation results to evaluate their effectiveness in representing heterogeneities. This study concludes, in part, that the extent of vertical communication in the reservoir determines which of the pseudo curve calculation methods will best represent the heterogeneity, and that a previously proposed dimensionless number, RL, adequately determines the extent of vertical communication in the reservoir.
Modeling of Permeability Reducing Vertical Conformance Treatments
Creators: name: Tsau, Jyun-Syung
Publisher: name: The University of Texas at Austin
Year: 1985
Subjects: Conformance
Permeability

description: Chemical treatments (usually polymer gels) are commonly used to improve the vertical conformance of oil reservoirs by selectively reducing the permeability in some zones near the well. The resuIts of such treatments have been sporadic and unpredictable. The objective of this study is to define those reservoir characteristics which lead to successful treatments and to provide guidelines for the application of conformance treatments by modeling them with a reservoir simulator-. The computer simulator is the BOAST model, a multiphase, three-. dimensional finite difference model written by Fanchi J. R. et al. and released by the Department of Energy. It was modified in areas such as the restart procedure , the rate allocation scheme, condition of well constraint, interpretation of relative permeability and implicit rate calculation to meet the objectives of this study. Several cases have been run to identify the reservoir properties that strongly influence the outcome of a conformance treatment. These are the vertical permeability, the permeability thickness product contrast between layers, the permeability contrast, and the level of permeability reduction near the injection well. The results presented interpret the test cases and provide a basis for possible implementation of a successful conformance treatment. Finality, a field case is presented in which actual reservoir properties were used to study a conformance treatment.
An Experimental Study of the Effect of Instability on Dynamic Displacement Relative Permeability Measurements
Creators: name: Khataniar, Santanu
Publisher: name: The University of Texas at Austin
Year: 1985
Subjects: Dynamic displacement
Permeability

description: An experimental study was undertaken to investigate the effects of instability on oil and water relative permeabilities measured by the dynamic displacement method. The calculation of relative permeability from dynamic displacement data assumes a stable displacement of oil by water. This assumption is no longer valid when the displacement becomes unstable. Therefore, the computed relative permeabilities are liable to be incorrect in such a situation. Dynamic displacement experiments were carried out using unconsolidated sand packs, refined oils and distilled water. Oil and water relative permeability curves were obtained by a standard calculation technique. The degree of instability of the displacements was varied by varying a dimensionless stability number. The higher the stability number, the higher is the degree of instability. One steady state experiment also was carried out to obtain a set of control data. The results show that instability has a significant effect on both oil and water relative permeability curves, obtained from dynamic displacement data. In general, the oil relative permeabilities decreased and the water relative permeabilities increased with increasing stability number. Therefore, it is necessary to conduct dynamic displacement experiments under stable displacement conditions in order to obtain the true relative permeability curves for the fluid-rock system.
Characterization of Process Air Emissions in Automotive Production Plants
Creators: name: J. B. D’Arcy
name: J. M. Dasch
name: A. B. Gundrum
name: J. L. Rivera
name: J. H. Johnson
name: D. H. Carlson
name: J. W. Sutherland
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Evolutionary Biology
subject: Biophysics

description: ABSTRACTDuring manufacturing, particles produced from industrial processes become airborne. These airborne emissions represent a challenge from an industrial hygiene and environmental standpoint. A study was undertaken to characterize the particles associated with a variety of manufacturing processes found in the auto industry. Air particulates were collected in five automotive plants covering ten manufacturing processes in the areas of casting, machining, heat treatment and assembly. Collection procedures provided information on air concentration, size distribution and chemical composition of the airborne particulate matter for each process and insight into the physical and chemical processes that created those particles.
A Synthesis of Hidden Subgroup Quantum Algorithms and Quantum Chemical Dynamics
Creators: name: Iyengar, Srinivasan S.
name: Kumar, Anup
name: Saha, Debadrita
name: Sabry, Amr
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We describe a general formalism for quantum dynamics and show how this formalism subsumes several quantum algorithms including the Deutsch, Deutsch-Jozsa, Bernstein-Vazirani, Simon, and Shor algorithms as well as the conventional approach to quantum dynamics based on tensor networks. The common framework exposes similarities among quantum algorithms and natural quantum phenomena: we illustrate this connection by showing how the correlated behavior of protons in water wire systems that are common in many biological and materials systems parallels the structure of Shor's algorithm.
Geographic/ethnic variability of chromosomal and molecular abnormalities in leukemia
Creators: name: Braekeleer, Marc De
name: Braekeleer, Etienne De
name: Douet-Guilbert, Nathalie
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Cancer
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Molecular Biology
subject: Genetics

description: In 1963, Jean Bernard, a French hematologist, opened a new chapter in hematology called geographic hematology (‘Hématologie Géographique’). He distinguished two research avenues. One dealt with the differences between the various populations (ethnic hematology), the other with various environmental factors (environmental hematology). In recent years, focus has been put on analyzing the genetic susceptibility in cancer and hematological malignancies, particularly in childhood acute lymphoblastic leukemia, using specific gene or (genome-wide association study) approach. However, almost 30 years ago, it was suggested by a few workers that chromosomal abnormalities observed in leukemia could have a geographic and/or ethnic distribution. In this review, we analyze the literature on chromosomal and molecular abnormalities in several types of leukemia.
Accurate delay distribution for IEEE 802.11 DCF
Creators: name: Vu, Hai
name: Sakurai, Taka
Publisher: name: Swinburne
Year: 2024

description: We derive the access delay generating function of the IEEE 802.11 DCF protocol. Our analysis corrects a model recently presented in [6]. We demonstrate that numerical transform inversion can be used to efficiently obtain values of the distribution. Simulations show that our analytical results are highly accurate.
Cydnoseius Muma 1967
Creators: name: ZahidiK, Abdelaziz
name: Akchour, Abdellah
name: K, Serge Kreiter
name: TixierK, Marie-Stéphane
name: MsandaK, Fouad
name: MousadikK, Abdelhamid El
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Phytoseiidae
Cydnoseius

description: Genus Cydnoseius Muma
 Cydnoseius Muma 1967: 274.
description: Published as part of ZahidiK, Abdelaziz, Akchour, Abdellah, K, Serge Kreiter, TixierK, Marie-Stéphane, MsandaK, Fouad & MousadikK, Abdelhamid El, 2023, Phytoseiid mites (Acari: Mesostigmata) from Central West Morocco: new records and key to females of all recorded Moroccan species, pp. 691-724 in Acarologia 63 (3) on page 706, DOI: 10.24349/v5of-5oe1, http://zenodo.org/record/10786247
Alburnoides holciki Coad & BogutsKaya 2012
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Alburnoides
Alburnoides holciki

description: 172. Alburnoides holciki Coad & BogutsKaya, 2012
Common name. Spirlin
Taxonomy. Original description: Alburnoides holciki Coad & BogutsKaya, 2012: 44, figs. 1-2 [Hari River at Herat, 34°20'N, 62°12'E, Afghanistan; holotype: SNMB 6788].
Revisions. None.
Illustrations. Coad & Bogutskaya (2012: figs. 1-2).
Distribution in Iran. —Distribution in River Basin: Hari River, Caspian Sea.—Distribution in Ecoregions: 450-Turan Plain, 631-Upper Amu Darya.
Status in Iran. [Native].—Khayateh–e Holicik.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018); Jouladeh-Roudbar et al. (2020); Eagderi et al. (2022). Iran material: None.
Conservation. —IUCN: NE.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on pages 56-57, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
Detecting Severity of Diabetic Retinopathy from Fundus Images: A Transformer Network-based Review
Creators: name: Karkera, Tejas
name: Adak, Chandranath
name: Chattopadhyay, Soumi
name: Saqib, Muhammad
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Diabetic Retinopathy (DR) is considered one of the significant concerns worldwide, primarily due to its impact on causing vision loss among most people with diabetes. The severity of DR is typically comprehended manually by ophthalmologists from fundus photography-based retina images. This paper deals with an automated understanding of the severity stages of DR. In the literature, researchers have focused on this automation using traditional machine learning-based algorithms and convolutional architectures. However, the past works hardly focused on essential parts of the retinal image to improve the model performance. In this study, we adopt and fine-tune transformer-based learning models to capture the crucial features of retinal images for a more nuanced understanding of DR severity. Additionally, we explore the effectiveness of image transformers to infer the degree of DR severity from fundus photographs. For experiments, we utilized the publicly available APTOS-2019 blindness detection dataset, where the performances of the transformer-based models were quite encouraging.
Chiral photonic crystals with four-fold symmetry: Band structure and S-parameters of eight-fold intergrown Gyroid nets
Creators: name: Saba, Matthias
name: Turner, Mark D.
name: Gu, Min
name: Mecke, Klaus
name: Schröder-Turk, Gerd E.
name: Friend, James
name: Tan, H. Hoe
Publisher: name: Swinburne
Year: 2024

description: The Single Gyroid, or srs, nanostructure has attracted interest as a circular-polarisation sensitive photonic material. We develop a group theoretical and scattering matrix method, applicable to any photonic crystal with symmetry I432, to demonstrate the remarkable chiral-optical properties of a generalised structure called 8-srs, obtained by intergrowth of eight equal-handed srs nets. Exploiting the presence of four-fold rotations, Bloch modes corresponding to the irreducible representations E- and E+ are identified as the sole and non-interacting transmission channels for right- and left-circularly polarised light, respectively. For plane waves incident on a finite slab of the 8-srs, the reflection rates for both circular polarisations are identical for all frequencies and transmission rates are identical up to a critical frequency below which scattering in the far field is restricted to zero grating order. Simulations show the optical activity of the lossless dielectric 8-srs to be large, comparable to metallic metamaterials, demonstrating its potential as a nanofabricated photonic material.
Pvt Simulators for Microcomputers
Creators: name: Tufts, Thomas Nathan
Publisher: name: The University of Texas at Austin
Year: 1986
Subjects: Pvt simulator
Petroleum fluid

description: Fluid analysis or pressure-volume-temperature (PVT) analysis of petroleum fluids can be obtained by either laboratory analysis, empirical correlations, or through the use of equations of state. Laboratory analysis is notably accurate but is expensive, time-consuming, and requires specialized equipment and personnel. Empirical correlations are readily available and easy to use but can have inherent inaccuracies because conditions vary from those in which the correlations were developed. Fluid analysis by si mu la ti on technique using equations of state requires complex computer calculations, which until recent advances in microcomputer technology, could only be performed on mainframe computers which were capable of handling the tedious calculations and large data storage. PVT simulators have been written on mainframe computers, but few have been adapted to the microcomputer, leaving the engineer with the option of costly laboratory analysis, inconvenient timesharing, or less precise empirical correlation. The purpose of this report was to modify a PVT simulator written for a mainframe computer to run on a microcomputer. PVTBO, PVTVO, and PVTGC are a set of petroleum fluid analysis programs which have been adapted to run on an IBM-PC microcomputer. The programs provide PVT properties of a black oil, a volatile oil, and a gas condensate system, respectively, based on the Peng-Robinson equation of state. The programs can run on an IBM-PC microcomputer with at least 192K memory. Input requirements are pressure, temperature, and over-all fluid composition. The outputs for the black oil and volatile oil system include phase compositions, solution gas-oil ratios, formation volume factors, oil densities, gas gravities, relative volumes, and oil and gas viscosities. In addition, the volatile oil system includes percent liquid and gas produced, and equivalent liquid recovery. The outputs for the gas condensate system include phase compositions, condensate liquid volumes, percent gas produced, relative volumes, gas formation factors, gas viscosities, equivalent liquid recoveries.
Alburnoides idignensis Bogutskaya & Coad 2009
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Alburnoides
Alburnoides idignensis

description: 173. Alburnoides idignensis Bogutskaya & Coad, 2009
Common name. Tigris spirlin
Taxonomy. Original description: Alburnoides idignensis Bogutskaya & Coad, 2009: 166, Fig. 13 [Bid Sorkh River between Sahneh and Kandgavar, Gav Masiab River drainage, ca. 34°23'N, 47°52'E, Kermanshahan, Iran, elevation 1370 m; holotype: CMNFI 2007-0118].
Revisions. None.
Illustrations: Bogutskaya & Coad (2009: 166, fig. 133).
Distribution in Iran. —Distribution in River Basin: Tigris.—Distribution in Ecoregions: 442-Upper Tigris & Euphrates.
Status in Iran. [Endemic].—Mahi-e Khayateh.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018) and Jouladeh-Roudbar et al. (2020).—Iran material: CMNFI.
Conservation. —IUCN: NE.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 57, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
Paraseiulini Wainstein
Creators: name: ZahidiK, Abdelaziz
name: Akchour, Abdellah
name: K, Serge Kreiter
name: TixierK, Marie-Stéphane
name: MsandaK, Fouad
name: MousadikK, Abdelhamid El
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Phytoseiidae

description: Tribe Paraseiulini Wainstein  Paraseiulini Wainstein 1976: 697.
description: Published as part of ZahidiK, Abdelaziz, Akchour, Abdellah, K, Serge Kreiter, TixierK, Marie-Stéphane, MsandaK, Fouad & MousadikK, Abdelhamid El, 2023, Phytoseiid mites (Acari: Mesostigmata) from Central West Morocco: new records and key to females of all recorded Moroccan species, pp. 691-724 in Acarologia 63 (3) on page 706, DOI: 10.24349/v5of-5oe1, http://zenodo.org/record/10786247
Projection predictive variable selection for discrete response families with finite support
Creators: name: Weber, Frank
name: Glass, Änne
name: Vehtari, Aki
Publisher: name: arXiv
Year: 2023
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences
subject: 62F15 (Primary) 62F07, 62J99 (Secondary)

description: The projection predictive variable selection is a decision-theoretically justified Bayesian variable selection approach achieving an outstanding trade-off between predictive performance and sparsity. Its projection problem is not easy to solve in general because it is based on the Kullback-Leibler divergence from a restricted posterior predictive distribution of the so-called reference model to the parameter-conditional predictive distribution of a candidate model. Previous work showed how this projection problem can be solved for response families employed in generalized linear models and how an approximate latent-space approach can be used for many other response families. Here, we present an exact projection method for all response families with discrete and finite support, called the augmented-data projection. A simulation study for an ordinal response family shows that the proposed method performs better than or similarly to the previously proposed approximate latent-space projection. The cost of the slightly better performance of the augmented-data projection is a substantial increase in runtime. Thus, in such cases, we recommend the latent projection in the early phase of a model-building workflow and the augmented-data projection for final results. The ordinal response family from our simulation study is supported by both projection methods, but we also include a real-world cancer subtyping example with a nominal response family, a case that is not supported by the latent projection.
description: This preprint has not undergone peer review (when applicable) or any post-submission improvements or corrections. The Version of Record of this article is published in Computational Statistics, and is available online at https://doi.org/10.1007/s00180-024-01506-0
A Simple Gravity Override Predictive Model of Steamdrive
Creators: name: Leung, Wing-Kai
Publisher: name: The University of Texas at Austin
Year: 1986
Subjects: Steamdrive
Predictive model

description: A predictive model for steamflooding, based on a predominantly steam override scenario, was developed and tested with twenty-three field cases reported in the literature. Acceptable matches were readily obtained with eighteen of them. Petrophysical, geological and operational parameters of the remaining five cases precluded use of the model. The current model proposes that oil is driven essentially downward from both steam and steam condensate zones to the cooler original oil zone below, and produced. Oil production rate is determined by the pre-steamflood oil production rate, the thickness of the oil zone, and thermal reduction of oil viscosity due to conductive heating. This is contrary to the generally accepted production mechanism, i.e. that growth of the steam zone is the principal determining factor of oil production. An "effective" steam condensate zone size was used to match the model to field production data. The developed model was found to be best applied to relatively thick reservoirs of small dip angle, with a medium heavy crude oil. Introduction of a "lag time" to account for steam breakthrough time and an areal sweep efficiency function expanded the the model's use to large pattern areas. Sensitivity studies were also carried out, and the results were compatible with other results in the literature. The model was further tested with a hypothetical case run on thermal simulators. The results agreed reasonably well with those obtained from the simulators.
Development of new methods for high-resolution large volume imaging for molecular biology
Creators: name: DIERICKX, DAVID ASHLEY
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 310902
subject: Animal cell and molecular biology
classificationCode: 321202
subject: Optical technology

description: For imaging in molecular biology, there is an ever increasing priority on observing cells in their native context. This has led to a number of state of the art imaging techniques, however they are often limited by complexity, price and accessibility. Across three modalities, the work in this thesis develops new protocols, software and hardware to enable higher level imaging through the reduction of required expertise, cost and system complexity. This includes novel excitation methods for light sheet generation, a semi-automated cryogenic sample preparation protocol, integration of advanced correlative light-electron microscopes and development of an exploration focused optical simulation suite.
Beta-blocker use in severe sepsis and septic shock: a systematic review
Creators: name: Sanfilippo, Filippo
name: Santonocito, Cristina
name: Morelli, Andrea
name: Foex, Pierre
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biotechnology
subject: Medicine

description: Objective:Recent growing evidence suggests that beta-blocker treatment could improve cardiovascular dynamics and possibly the outcome of patients admitted to intensive care with severe sepsis or septic shock.Design:Systematic review.Data sources:MEDLINE and EMBASE healthcare databases.Review methods:To investigate this topic, we conducted a systematic review of the above databases up to 31 May 2015. Due to the clinical novelty of the subject, we also included non-randomized clinical studies. We focused on the impact of beta-blocker treatment on mortality, also investigating its effects on cardiovascular, immune and metabolic function. Evidence from experimental studies was reviewed as well.Results:From the initial search we selected 10 relevant clinical studies. Five prospective studies (two randomized) assessed the hemodynamic effects of the beta1-blocker esmolol. Heart rate decreased significantly in all, but the impact on other parameters differed. The imbalance between prospective studies’ size (10 to 144 patients) and the differences in their design disfavor a meta-analysis. One retrospective study showed improved hemodynamics combining metoprolol and milrinone in septic patients, and another retrospective study found no association between beta-blocker administration and mortality. We also found three case series. Twenty-one experimental studies evaluated the hemodynamic, immune and/or metabolic effects of selective and/or non-selective beta-blockers in animal models of sepsis (dogs, mice, pigs, rats, sheep), yielding conflicting results.Conclusions:Whilst there is not enough prospective data to conduct a meta-analysis, the available clinical data are promising. We discuss the ability of beta blockade to modulate sepsis-induced alterations at cardiovascular, metabolic, immunologic and coagulation levels.
Paraseiulus Muma 1961
Creators: name: ZahidiK, Abdelaziz
name: Akchour, Abdellah
name: K, Serge Kreiter
name: TixierK, Marie-Stéphane
name: MsandaK, Fouad
name: MousadikK, Abdelhamid El
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Phytoseiidae
Paraseiulus

description: Genus Paraseiulus Muma
 Paraseiulus Muma, 1961: 299.
description: Published as part of ZahidiK, Abdelaziz, Akchour, Abdellah, K, Serge Kreiter, TixierK, Marie-Stéphane, MsandaK, Fouad & MousadikK, Abdelhamid El, 2023, Phytoseiid mites (Acari: Mesostigmata) from Central West Morocco: new records and key to females of all recorded Moroccan species, pp. 691-724 in Acarologia 63 (3) on page 706, DOI: 10.24349/v5of-5oe1, http://zenodo.org/record/10786247
Cluster root allocation of white lupin (Lupinus albus L.) in soil with heterogeneous phosphorus and water distribution
Creators: name: Schulin, Rainer
name: Felderer, Bernd
name: Vontobel, Peter
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Engineering

description: Cluster roots are structures formed by many plants adapted to phosphorus (P)-deficient soils. We investigated the combined influence of spatial heterogeneity in soil water and P distribution on the allocation of cluster root formation in white lupin (Lupinus albus L.). In this study, single plants were grown at a low or a high rate of water supply in containers filled with a P-poor sand to which either no P was added or which was fertilized homogeneously or heterogeneously. Furthermore, heterogeneous soil water distribution was established in half of the containers by using a finer instead of a coarser sand in a lateral third of the containers. Plant growth increased with water supply rate, but P fertilization had no influence on shoot biomass production. Although overall cluster root production decreased with increasing homogeneous P supply, localized P fertilization had no effect on cluster root allocation. However, cluster roots were preferentially allocated in the soil sections with lower water availability when overall water supply rate was low. The results suggest that overall cluster root production was a systemic response to initial plant P status, while cluster root growth was stimulated locally in drier patches when overall water supply was limiting plant growth.
Alburnoides namaki Bogutskaya & Coad 2009
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Alburnoides
Alburnoides namaki

description: 174. Alburnoides namaki Bogutskaya & Coad, 2009
Common name. Namak spirlin-Namak riffle minnow
Taxonomy. Original description: Alburnoides namaki Bogutskaya & Coad, 2009: 159, fig. 11 [Qanat at Taveh, 35°07'N, 49°02'E, Hamadan, Iran, elevation 1640 meters; holotype: CMNFI 1979-0461].
Revisions. None.
Illustrations. Bogutskaya & Coad (2009: 159, fig. 11).
Distribution in Iran. — Distribution in River Basin: Namak Lake.—Distribution in Ecoregions: 447-Namak.
Status in Iran. [Endemic].—Khayateh-e Namak.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018) and Jouladeh-Roudbar et al. (2020).— Iran material: CMNFI.
Conservation. —IUCN: NE.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 57, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097