cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Central Moment Discrepancy (CMD) for Domain-Invariant Representation Learning
Creators: name: Zellinger, Werner
name: Grubinger, Thomas
name: Lughofer, Edwin
name: Natschläger, Thomas
name: Saminger-Platz, Susanne
Publisher: name: arXiv
Year: 2017
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: 68T05

description: The learning of domain-invariant representations in the context of domain adaptation with neural networks is considered. We propose a new regularization method that minimizes the discrepancy between domain-specific latent feature representations directly in the hidden activation space. Although some standard distribution matching approaches exist that can be interpreted as the matching of weighted sums of moments, e.g. Maximum Mean Discrepancy (MMD), an explicit order-wise matching of higher order moments has not been considered before. We propose to match the higher order central moments of probability distributions by means of order-wise moment differences. Our model does not require computationally expensive distance and kernel matrix computations. We utilize the equivalent representation of probability distributions by moment sequences to define a new distance function, called Central Moment Discrepancy (CMD). We prove that CMD is a metric on the set of probability distributions on a compact interval. We further prove that convergence of probability distributions on compact intervals w.r.t. the new metric implies convergence in distribution of the respective random variables. We test our approach on two different benchmark data sets for object recognition (Office) and sentiment analysis of product reviews (Amazon reviews). CMD achieves a new state-of-the-art performance on most domain adaptation tasks of Office and outperforms networks trained with MMD, Variational Fair Autoencoders and Domain Adversarial Neural Networks on Amazon reviews. In addition, a post-hoc parameter sensitivity analysis shows that the new approach is stable w.r.t. parameter changes in a certain interval. The source code of the experiments is publicly available.
description: Extended journal version published: https://doi.org/10.1016/j.ins.2019.01.025
Using EdTech in Settings of Fragility, Conflict and Violence: A Curated Resource List
Creators: name: Saalim Koomar
name: Coflan, Caitlin Moss
name: Kaye, Tom
Publisher: name: Zenodo
Year: 2020

description: This curated list of resources collates interventions that effectively deploy education technology in settings of fragility, conflict and violence (FCV). The World Bank (2020) states that by 2030 FCV settings will be home to up to two thirds of the world’s extreme poor; these settings have become increasingly complex over the past decade, with the COVID-19 pandemic threatening to exacerbate existing challenges. This list explores effective uses of EdTech in FCV settings. It particularly emphasises interventions and evidence relevant to the Yemeni context and distance learning during the COVID-19 crisis. These resources were selected with the intention to include practical recommendations on technology-enabled interventions which could support a proposed national distance learning system in Yemen.
A direct proof of dimerization in a family of SU(n)-invariant quantum spin chains
Creators: name: Nachtergaele, Bruno
name: Ueltschi, Daniel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences
subject: 82B10, 82B20, 82B26

description: We study the family of spin-S quantum spin chains with a nearest neighbor interaction given by the negative of the singlet projection operator. Using a random loop representation of the partition function in the limit of zero temperature and standard techniques of classical statistical mechanics, we prove dimerization for all sufficiently large values of S.
description: 14 pages, 7 figures, updated to published version and one footnote added
Averages of $b$-hadron, $c$-hadron, and $τ$-lepton properties as of summer 2016
Creators: name: Heavy Flavor Averaging Group
name: Amhis, Y.
name: Banerjee, Sw.
name: Ben-Haim, E.
name: Bernlochner, F.
name: Bozek, A.
name: Bozzi, C.
name: Chrząszcz, M.
name: Dingfelder, J.
name: Duell, S.
name: Gersabeck, M.
name: Gershon, T.
name: Gerstel, D.
name: Goldenzweig, P.
name: Harr, R.
name: Hayasaka, K.
name: Hayashii, H.
name: Kenzie, M.
name: Kuhr, T.
name: Leroy, O.
name: Lusiani, A.
name: Lyu, X. R.
name: Miyabayashi, K.
name: Naik, P.
name: Nanut, T.
name: Campos, A. Oyanguren
name: Patel, M.
name: Pedrini, D.
name: Petrič, M.
name: Rama, M.
name: Roney, M.
name: Rotondo, M.
name: Schneider, O.
name: Schwanda, C.
name: Schwartz, A. J.
name: Serrano, J.
name: Shwartz, B.
name: Tesarek, R.
name: Tonelli, D.
name: Trabelsi, K.
name: Urquijo, P.
name: Van Kooten, R.
name: Yelton, J.
name: Zupanc, A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: This article reports world averages of measurements of $b$-hadron, $c$-hadron, and $τ$-lepton properties obtained by the Heavy Flavor Averaging Group using results available through summer 2016. For the averaging, common input parameters used in the various analyses are adjusted (rescaled) to common values, and known correlations are taken into account. The averages include branching fractions, lifetimes, neutral meson mixing parameters, \CP~violation parameters, parameters of semileptonic decays and CKM matrix elements.
description: 498 pages, 293 figures, many tables. Online updates available at http://www.slac.stanford.edu/xorg/hflav/. v2 updated with important improvements. v3 corresponds to published version
Brief an Joh[ann] Rudolf Stucki
Creators: name: Manz, Konrad
Publisher: name: [s.n.]
Year: 1659

description: von Joh[ann] Conr[ad] Manz
description: Mit rotem Lacksiegel
description: Das zweite Blatt ist das Couvert
description: Lateinisch
description: Verzeichnung=Description=Inventaire April 2012 Vollständige Rekatalogisierung nach Standortverzeichnis Frey-Gryn Mscr I 4-I 24, Briefkatalog und Vorlage
title: 'Them women be best man for missions' : women and missions in nineteenth-century British West Africa
Creators: name: Jolliffe, Clive
Publisher: name: University of Kent
Year: 2022

description: Africa occupies a special place within missionary history. It was seen in the nineteenth century as the dark continent which needed to be saved and missionaries set out to do this. The thesis shows how women were essential to this effort. It was not just the wives, widows and single female missionaries who worked overseas who were vital for missionary work but also essential were those women who worked at home to provide the support necessary for missionary enterprise. The West African women whom the missionaries believed they came to save were also an important aspect of missionary work. The thesis looks at how all these women came together in the missionary effort in British West Africa from the beginning of the 19th century to the end of W.W.I., placing them in the context of contemporary society. The work of five major missionary societies is looked at in the four countries which eventually comprised British West Africa. Missionary work was one of the few areas in the 19th century which women could appropriate. It was not just overseas that they could do this. In Britain they were able to control and run large organisations which provided opportunities for women to show what they could do given the opportunity. The Women’s Auxiliary of the Wesleyan Methodist Missionary Society was one such organisation and is examined in the thesis, as is the training and recruitment of female candidates. In West Africa wives, widows and single female agents all made their own important contributions to the missionary work. They developed a wide range of skills, especially in working with local women and children. This thesis examines the ways in which they did this and also what they were not able to do. The missionary heroine was an important part of the promotion of the missionary cause and her role is looked at and compared with the depiction of missionary women in 19th century fiction. The missionaries came to change society in West Africa and local women were not exempted. Missionaries brought with them ideas about polygyny and domestic slavery which affected women particularly. What this meant for African women and how they responded is a particular feature of the thesis.
Characterizing Cellular Vulnerability in Response to Acute and Repeated Cold Exposure in Young and Older Adults
Creators: name: King, Kelli Elizabeth
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2024
Subjects: autophagy
cold
aging
acclimation
apoptosis
inflammation

description: Introduction: Cold exposure is a challenging environmental stimulus for humans, particularly in vulnerable populations such as older adults. Decrements in cold tolerance observed in older adults may be mediated by an age-related reduction in the stress-induced cytoprotective mechanism of autophagy, which enhances cell survival by eliminating damaged cellular components. However, it is unknown how autophagy and accompanying cytoprotective pathways (i.e., heat shock proteins) respond to cold conditions in humans. Purpose: The purpose of this thesis was to evaluate the impact of aging on autophagic activity during cold exposure and assess strategies to reverse age-related autophagic dysfunction. Methods: We examined the influence of age on autophagy during acute cold exposure utilizing ex vivo, in vitro, and in vivo models in young (19-29 years) and older (54-76 years) adults. Autophagic activity in all investigations was assessed in peripheral blood mononuclear cells (i.e., immune cells) via Western blotting. Simulated hypothermic conditions (equivalent to 4-35°C core temperature) were evaluated using ex vivo whole-blood exposure. In vivo cold stress was achieved using cold-water immersions to elicit a physiologically relevant decrease in core temperature by 0.5 and 1.0°C. Techniques that potentially reversed autophagic impairments during cold exposure were assessed including, 1) an in vitro treatment of a known autophagic stimulator (rapamycin) in immune cells obtained from young and older males, and 2) an in vivo cold acclimation in young males with cold-water immersions (14°C for 60 min) repeated on 7 consecutive days. Results: Simulated hypothermia (4-35°C) induced autophagic dysfunction regardless of age or sex. Moderate cold stress (a 0.5°C reduction in core temperature) stimulated autophagy in young males. However, intense cold exposures (equivalent to ≥ 1.0°C decrease in core temperature) elicited signs of autophagic dysfunction and a shift towards apoptotic cell death. Additionally, older adults displayed evidence of autophagic dysfunction during each cold exposure, although age-related autophagic dysfunction was mitigated with acute rapamycin treatment. Further, cold acclimation robustly improved autophagic responses to cold exposure. Conclusion: Despite an observed age-related impairment in autophagic responses during cold exposure, this thesis provided the first evidence in humans that autophagic dysregulation during cold exposure can be reversed through the administration of autophagic stimulators and through cold acclimation.
Understanding University Students' Perceptions and Attributions in Linguistically Diverse Mathematics Classrooms
Creators: name: Zhao, Yutao
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2024
Subjects: mathematics education
language diversity
higher education

description: In recent years, the number of multilingual international students in Canadian university mathematics classrooms is on the rise, and a substantial body of literature has emerged on the topic of language diversity in mathematics education (e.g., Barwell et al., 2019; Chronaki & Planas, 2018; Suh, 2020; Tai, 2021). Whilst much research has been carried out in linguistically diverse settings, no single study exists which explores students' social perceptions of their peers in linguistically diverse mathematics classrooms. In addition, there is scant research conducted in post-secondary classrooms. The primary objective of the study is to fill the research gap by examining the factors that university students consider significant in their mathematics learning and exploring how students attribute both their own and others' successes and failures during mathematical discussions in linguistically diverse university classrooms. The study recruited nine participants from diverse linguistic backgrounds who have or were currently studying mathematics at the postsecondary level. Data collection was conducted through the utilization of group discussion, focus group interviews, and semi-structured interviews. This research contributes to a deeper understanding of university students' experiences in linguistically diverse mathematics classrooms and promotes university internationalization and positive student experiences.
Super-Ricci flows and improved gradient and transport estimates
Creators: name: Kopfer, Eva
Publisher: name: arXiv
Year: 2017
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We show that the heat flow on super-Ricci flows in the sense of Sturm satisfies transport estimates with respect to every $L^p$-Kantorovich distance, $p\in[1,\infty]$. As an application we construct Brownian motions on time-dependent metric measure spaces and present transport estimates for their trajectories. The proof is inspired by the approach from Savaré and Bakry respectively and takes advantage of the self-improvement of the gradient estimates. For this we prove a refined version of Bochner's inequality under strengthened assumptions on the metric.
description: This is a revised version. To appear in "Probability Theory and Related Fields"
Existence, Uniqueness and Structure of Second Order absolute minimisers
Creators: name: Katzourakis, Nikos
name: Moser, Roger
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: Let $Ω\subseteq \mathbb{R}^n$ be a bounded open $C^{1,1}$ set. In this paper we prove the existence of a unique second order absolute minimiser $u_\infty$ of the functional \[ \mathrm{E}_\infty (u,\mathcal{O})\, :=\, \| \mathrm{F}(\cdot, Δu) \|_{L^\infty( \mathcal{O} )}, \ \ \ \mathcal{O} \subseteq Ω\text{ measurable}, \] with prescribed boundary conditions for $u$ and $\mathrm{D} u$ on $\partial Ω$ and under natural assumptions on $\mathrm{F}$. We also show that $u_\infty$ is partially smooth and there exists a harmonic function $f_\infty \in L^1(Ω)$ such that \[ \mathrm{F}(x, Δu_\infty(x)) \, =\, e_\infty\, \mathrm{sgn}\big(f_\infty(x)\big) \] for all $x \in \{f_\infty \neq 0\}$, where $e_\infty$ is the infimum of the global energy.
description: 17 pages; Journal: Archives for Rational Mechanics and Analysis
On Stochastic Stability of a Class of non-Markovian Processes and Applications in Quantization
Creators: name: Yüksel, Serdar
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: In many applications, the common assumption that a driving noise process affecting a system is independent or Markovian may not be realistic, but the noise process may be assumed to be stationary. To study such problems, this paper investigates stochastic stability properties of a class of non-Markovian processes, where the existence of a stationary measure, asymptotic mean stationarity and ergodicity conditions are studied. Applications in feedback quantization and stochastic control are presented.
description: A clarification in the statement of Theorem 3.9 (on Assumption 2.3 for the applications)
FAST Adaptive Smoothing and Thresholding for Improved Activation Detection in Low-Signal fMRI
Creators: name: Almodóvar-Rivera, Israel
name: Maitra, Ranjan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Methodology (stat.ME)
subject: Statistics Theory (math.ST)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 62P10, 62P30, 62E20, 62H10, 62H35

description: Functional Magnetic Resonance Imaging is a noninvasive tool for studying cerebral function. Many factors challenge activation detection, especially in low-signal scenarios that arise in the performance of high-level cognitive tasks. We provide a fully automated fast adaptive smoothing and thresholding (FAST) algorithm that uses smoothing and extreme value theory on correlated statistical parametric maps for thresholding. Performance on experiments spanning a range of low-signal settings is very encouraging. The methodology also performs well in a study to identify the cerebral regions that perceive only-auditory-reliable or only-visual-reliable speech stimuli.
description: 26 pages, 2 tables, 19 figures. Accepted for publication in IEEE Transactions on Medical Imaging
Extensions of the Benson-Solomon fusion systems
Creators: name: Henke, Ellen
name: Lynd, Justin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20D20, 20D05

description: The Benson-Solomon systems comprise the only known family of simple saturated fusion systems at the prime two that do not arise as the fusion system of any finite group. We determine the automorphism groups and the possible almost simple extensions of these systems and of their centric linking systems.
description: v1: 14 pages; v2: minor changes; v3: typo fixing
Loop quantum cosmology and singularities
Creators: name: Struyve, Ward
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Loop quantum gravity is believed to eliminate singularities such as the big bang and big crunch singularity. This belief is based on studies of so-called loop quantum cosmology which concerns symmetry-reduced models of quantum gravity. In this paper, the problem of singularities is analysed in the context of the Bohmian formulation of loop quantum cosmology. In this formulation there is an actual metric in addition to the wave function, which evolves stochastically (rather than deterministically as the case of the particle evolution in non-relativistic Bohmian mechanics). Thus a singularity occurs whenever this actual metric is singular. It is shown that in the loop quantum cosmology for a homogeneous and isotropic Friedmann-Lemaitre-Robertson-Walker space-time with arbitrary constant spatial curvature and cosmological constant, coupled to a massless homogeneous scalar field, a big bang or big crunch singularity is never obtained. This should be contrasted with the fact that in the Bohmian formulation of the Wheeler-DeWitt theory singularities may exist.
description: 17 pages, no figures, LaTeX; v2 minor improvements
Fumetto e illustrazione
Creators: name: Dal Cortivo, Sara
Publisher: name: Medea
Year: 2023

description: In vista della compilazione della mia tesi di laurea, dedicata al fumettista rivoluzionario Jean Giraud aka Moebius, ho avuto l’opportunità d’intervistare due grandi disegnatori e autori di fumetti, soci fondatori della Scuola Romana dei fumetti e miei maestri: Eugenio Sicomoro e Massimo Rotundo. Il criterio adottato nella formulazione delle domande ha posto l’attenzione innanzitutto sul percorso professionale dei due autori, inserito in entrambi i casi nel panorama del fumetto europeo fin dagli anni ‘80. Sia Sicomoro che Rotundo, infatti, sono riusciti ad avere voce nell’editoria franco-belga fin da giovane età. Seguono le trascrizioni delle interviste integrali e inedite in cui si approfondiscono diversi aspetti: il percorso artistico e personale; i rapporti e le differenze tra fumetto italiano e fumetto francese; i meccanismi dell’editoria degli anni ’80 e ’90; il ruolo delle riviste; il rapporto tra cinema e fumetto; il ruolo degli storyboard artist; uno sguardo attento sul lavoro del grande fumettista e visionario Jean Giraud, che i due maestri hanno avuto la fortuna di conoscere personalmente.
description: Medea, V. 9 N. 1 (2023): Volume 9
Exploring the Categorical Nature of Colour Perception: Insights from Artificial Networks
Creators: name: Akbarinia, Arash
Publisher: name: Zenodo
Year: 2024

description: All research materials, including the source code for training/testing artificial neural networks and analysing the data for the article "Exploring the Categorical Nature of Colour Perception: Insights from Deep Networks".

The "results.zip" contains the raw results for all the examined artificial networks.

The "source_code.zip" contains the code to (1) train a linear classifier on top of features extracted from a frozen pretrained network, and (2) to test the colour categories in an odd-one-out task.
BRIDGING THE GAP: ASSESSING THE RELATIVE EFFICIENCY OF BANK AND MARKET FINANCE IN CAMEROON'S ECONOMIC LANDSCAPE
Creators: name: Abdalaziz, O. Zedou
name: Alizar, M. Zarma
Publisher: name: ZAP journals
Year: 2024
Subjects: Cameroon
Financial System
Economic Growth
National Strategy
DSCE

description: In the pursuit of Cameroon's 2020 objectives outlined in the National Strategy (DSCE), a critical question arises: do banks and market finance in Cameroon complement or compete with each other? This query gains significance amid the challenges that led to the unmet targets of the DSCE. Despite a slight increase in average growth from 3% under the Poverty Reduction Strategy Paper (PRSP), the growth during the period 2010-2020 remains below the anticipated 5.5% growth rate set by the DSCE. The underperformance is often attributed to external factors such as the fall in oil prices and security shocks in several regions of the country. Contrary to these common attributions, this paper contends that the primary cause of Cameroon's suboptimal economic performance lies within the failures of its financial system.

The ambitious objectives set forth in Cameroon's National Strategy (DSCE) for the year 2020 have encountered substantial challenges, prompting a critical examination of the dynamics between banks and market finance in the country. Despite concerted efforts, the average growth, which previously stood at 3% under the Poverty Reduction Strategy Paper (PRSP), marginally increased during the period of 2010-2020, failing to meet the DSCE's targeted growth rate of 5.5%. This discrepancy prompts a reevaluation of the perceived culprits, often ascribed to external factors like the impact of falling oil prices and security shocks affecting specific regions, including the far north, east, north-west, and south-west.

However, this paper posits an alternative perspective by emphasizing the inadequacies within Cameroon's financial system as the principal driver behind its economic underperformance. Rather than attributing the missed targets solely to external shocks, the focus shifts to the internal mechanisms of the financial sector. The exploration delves into the interplay between banks and market finance, aiming to discern whether they operate in tandem, reinforcing each other, or if there exists a competitive dynamic hindering the nation's economic growth.

In the subsequent analysis, we scrutinize instances of financial system failures as key contributors to Cameroon's economic challenges. By addressing these internal deficiencies, this research seeks to provide a nuanced understanding of the factors impeding the realization of national economic goals. Ultimately, the findings aim to inform policy discussions and strategic initiatives, fostering a more robust financial system that can better support and propel Cameroon towards its economic objectives.
Does Quartessence Ease Tensions?
Creators: name: Camera, Stefano
name: Martinelli, Matteo
name: Bertacca, Daniele
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Tensions between cosmic microwave background observations and the growth of the large-scale structure inferred from late-time probes pose a serious challenge to the concordance $Λ$CDM cosmological model. State-of-the-art data from the Planck satellite predicts a higher rate of structure growth than what preferred by low-redshift observables. Such tension has hitherto eluded conclusive explanations in terms of straightforward modifications to $Λ$CDM, e.g. the inclusion of massive neutrinos or a dynamical dark energy component. Here, we investigate models of 'quartessence' -- a single dark component mimicking both dark matter and dark energy -- whose non-vanishing sound speed inhibits structure growth at late times on scales smaller than its corresponding Jeans' length. In principle, this could reconcile high- and low-redshift observations. We put this hypothesis to test against temperature and polarisation spectra from the latest Planck release, SDSS DR12 measurements of baryon acoustic oscillations and redshift-space distortions, and cosmic shear correlation functions from KiDS. This the first time that any specific model of quartessence is applied to actual data. We show that, if we naively apply $Λ$CDM nonlinear prescription to quartessence, the combined data sets allow for tight constraints on the model parameters. Apparently, quartessence alleviates the tension between the total matter fraction and late-time structure clustering, although in fact the tension is transferred from the latter to the quartessence sound speed parameter. However, we found that this strongly depends upon information from nonlinear scales. Indeed, if we relax this assumption, quartessence models appear still viable. For this reason, we argue that the nonlinear behaviour of quartessence deserves further investigation and may lead to a deeper understanding of the physics of the dark Universe.
description: 8 pages, 6 figures, 1 table; matching published version
Geohyperbolic Routing and Addressing Schemes
Creators: name: Voitalov, Ivan
name: Aldecoa, Rodrigo
name: Wang, Lan
name: Krioukov, Dmitri
Publisher: name: arXiv
Year: 2017
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences
subject: C.2.1; C.2.2

description: The key requirement to routing in any telecommunication network, and especially in Internet-of-Things (IoT) networks, is scalability. Routing must route packets between any source and destination in the network without incurring unmanageable routing overhead that grows quickly with increasing network size and dynamics. Here we present an addressing scheme and a coupled network topology design scheme that guarantee essentially optimal routing scalability. The FIB sizes are as small as they can be, equal to the number of adjacencies a node has, while the routing control overhead is minimized as nearly zero routing control messages are exchanged even upon catastrophic failures in the network. The key new ingredient is the addressing scheme, which is purely local, based only on geographic coordinates of nodes and a centrality measure, and does not require any sophisticated non-local computations or global network topology knowledge for network embedding. The price paid for these benefits is that network topology cannot be arbitrary but should follow a specific design, resulting in Internet-like topologies. The proposed schemes can be most easily deployed in overlay networks, and also in other network deployments, where geolocation information is available, and where network topology can grow following the design specifications.
description: 6 pages, 1 figure
LIGAND-BASED DRUG DESIGN STUDIES ON SOME SELECTED CHEMICAL ACTIVATORS OF APOPTOSIS REGULATOR (BCL-2) FOR CANCEROUS CELL INHIBITION
Creators: name: Arthur, David Ebuka
Publisher: name: JSR Unimaid
Year: 2024

description: ABSTRACT

In spite of the substantial increase in the study of cancer treatment over the past decades, the disease is still a serious global health challenge and poses a considerable study. B-cell lymphoma 2 (BCL-2) apoptosis regulators were identified as potential targets in eliminating cancer cells, due to their high affinity for Bcl-2 Associated X-protein (BAX protein) which functions as a tool for bringing death to any cell.  Hence, developing new BCL-2 activators with better therapeutic effect is strongly needed. In an attempt to overcome this challenge, this research is aimed at developing a mathematical model that can be used in designing novel potent chemical moieties with better BCL-2 apoptosis regulator via prediction of their activities using a newly developed Quantitative structure activity relationship (QSAR) model. The material in the study includes the chemical dataset collected from pubmed, while the methods used are the standard QSAR development method as stated in the Setubal records. The main program used in the study is the QSARIN. The QSAR model developed in the study was presented as pEC50 = - 0.0148(ALogP) - 0.0043(nO) + 0.0144(nHBint8) - 0.6533(ETA_dEpsilon_B) + 5.2861. The model was selected for its effective use in predicting novel chemical compounds or test set found within the applicability domain of the model because it has the best statistical parameters such as: coefficient of determination (R2 = 0.7836), cross validation coefficient (Q2loo = 0.7094), and adjusted R2 (R2 adj = 0.7475). The models was able to predict the activity of the compounds used in developing the models, the validation statistical parameter for the test set were not as significant as that for the training set, but the result suggest that the model can be improved upon by applying other nonlinear modeling techniques like that of machine learning algorithm and support vector machine or by replacing the molecules identified as outliers and influential molecules in the data set with other molecules of similar structure.

Keywords: Cancer, QSAR, BCL-2, Density functional theory, QSARIN.
Deconvolution and Restoration of Optical Endomicroscopy Images
Creators: name: Eldaly, Ahmed Karam
name: Altmann, Yoann
name: Perperidis, Antonios
name: Krstajic, Nikola
name: Choudhary, Tushar
name: Dhaliwal, Kevin
name: McLaughlin, Stephen
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Optical endomicroscopy (OEM) is an emerging technology platform with preclinical and clinical imaging applications. Pulmonary OEM via fibre bundles has the potential to provide in vivo, in situ molecular signatures of disease such as infection and inflammation. However, enhancing the quality of data acquired by this technique for better visualization and subsequent analysis remains a challenging problem. Cross coupling between fiber cores and sparse sampling by imaging fiber bundles are the main reasons for image degradation, and poor detection performance (i.e., inflammation, bacteria, etc.). In this work, we address the problem of deconvolution and restoration of OEM data. We propose a hierarchical Bayesian model to solve this problem and compare three estimation algorithms to exploit the resulting joint posterior distribution. The first method is based on Markov chain Monte Carlo (MCMC) methods, however, it exhibits a relatively long computational time. The second and third algorithms deal with this issue and are based on a variational Bayes (VB) approach and an alternating direction method of multipliers (ADMM) algorithm respectively. Results on both synthetic and real datasets illustrate the effectiveness of the proposed methods for restoration of OEM images.
Leading order relativistic hyperon-nucleon interactions in chiral effective field theory
Creators: name: Li, Kai-Wen
name: Ren, Xiu-Lei
name: Geng, Li-Sheng
name: Long, Bing-Wei
Publisher: name: arXiv
Year: 2016
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We apply a recently proposed covariant power counting in nucleon-nucleon interactions to study strangeness $S=-1$ $ΛN-ΣN$ interactions in chiral effective field theory. At leading order, Lorentz invariance introduces 12 low energy constants, in contrast to the heavy baryon approach, where only five appear. The Kadyshevsky equation is adopted to resum the potential in order to account for the non-perturbative nature of hyperon-nucleon interactions. A fit to the $36$ hyperon-nucleon scattering data points yields $χ^2\simeq 16$, which is comparable with the sophisticated phenomenological models and the next-to-leading order heavy baryon approach. However, one cannot achieve a simultaneous description of the nucleon-nucleon phase shifts and strangeness $S=-1$ hyperon-nucleon scattering data at leading order.
description: 14 pages, 8 figures
Optimal follow-up observations of gravitational wave events with small optical telescopes
Creators: name: Narikawa, Tatsuya
name: Kaneyama, Masato
name: Tagoshi, Hideyuki
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We discuss optimal strategy for follow-up observations by 1-3 m class optical/infrared telescopes which target optical/infrared counterparts of gravitational wave events detected with two laser interferometric gravitational wave detectors. The probability maps of transient sources, such as coalescing neutron stars and/or black holes, determined by two laser interferometers generally spread widely. They include the distant region where it is difficult for small aperture telescopes to observe the optical/infrared counterparts. For small telescopes, there is a possibility that it is more advantageous to search for nearby region even if the probability inferred by two gravitational wave detectors is low. We show that in the case of the first three events of advanced LIGO, the posterior probability map, derived by using a distance prior restricted to a nearby region, is different from that derived without such restriction. This suggests that the optimal strategy for small telescopes to perform follow-up observation of LIGO-Virgo's three events are different from what has been searched so far. We also show that, when the binary is nearly edge-on, it is possible that the true direction is not included in the 90% posterior probability region. We discuss the optimal strategy to perform optical/infrared follow-up observation with small aperture telescopes based on these facts.
description: 12 pages, 6 figures, accepted for publication in Phys. Rev. D, added cases of design sensitivities
MPEC 2023-P75 : 2023 PH1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 PH1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
The $L^2$-torsion polytope of amenable groups
Creators: name: Funke, Florian
Publisher: name: arXiv
Year: 2017
Subjects: subject: Group Theory (math.GR)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics

description: We introduce the notion of groups of polytope class and show that torsion-free amenable groups satisfying the Atiyah Conjecture possess this property. A direct consequence is the homotopy invariance of the $L^2$-torsion polytope among $G$-CW-complexes for these groups. As another application we prove that the $L^2$-torsion polytope of an amenable group vanishes provided that it contains a non-abelian elementary amenable normal subgroup.
description: 21 pages
Radial measurements of IMF-sensitive absorption features in two massive ETGs
Creators: name: Vaughan, Sam P.
name: Davies, Roger L.
name: Zieleniewski, Simon
name: Houghton, Ryan C. W.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We make radial measurements of stellar initial mass function (IMF) sensitive absorption features in the two massive early-type galaxies NGC 1277 and IC 843. Using the Oxford Short Wavelength Integral Field SpecTrogaph (SWIFT), we obtain resolved measurements of the NaI0.82 and FeH0.99 indices, among others, finding both galaxies show strong gradients in NaI absorption combined with flat FeH profiles at $\sim0.4$Å. We find these measurements may be explained by radial gradients in the IMF, appropriate abundance gradients in [Na/Fe] and [Fe/H], or a combination of the two, and our data is unable to break this degeneracy. We also use full spectral fitting to infer global properties from an integrated spectrum of each object, deriving a unimodal IMF slope consistent with Salpeter in IC 843 ($x=2.27\pm0.17$) but steeper than Salpeter in NGC 1277 ($x=2.69\pm0.11$), despite their similar FeH equivalent widths. Independently, we fit the strength of the FeH feature and compare to the E-MILES and CvD12 stellar population libraries, finding agreement between the models. The IMF values derived in this way are in close agreement with those from spectral fitting in NGC 1277 ($x_{\mathrm{CvD}}=2.59^{+0.25}_{-0.48}$ , $x_{\mathrm{E-MILES}}=2.77\pm0.31$), but are less consistent in IC 843, with the IMF derived from FeH alone leading to steeper slopes than when fitting the full spectrum ($x_{\mathrm{CvD}}=2.57^{+0.30}_{-0.41}$, $x_{\mathrm{E-MILES}}=2.72\pm0.25$). This work highlights the importance of a large wavelength coverage for breaking the degeneracy between abundance and IMF variations, and may bring into doubt the use of the Wing-Ford band as an IMF index if used without other spectral information.
description: Accepted for publication in MNRAS. 21 pages, 15 figures
Implementing NLO DGLAP evolution in Parton Showers
Creators: name: Höche, Stefan
name: Krauss, Frank
name: Prestel, Stefan
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a parton shower which implements the DGLAP evolution of parton densities and fragmentation functions at next-to-leading order precision up to effects stemming from local four-momentum conservation. The Monte-Carlo simulation is based on including next-to-leading order collinear splitting functions in an existing parton shower and combining their soft enhanced contributions with the corresponding terms at leading order. Soft double counting is avoided by matching to the soft eikonal. Example results from two independent realizations of the algorithm, implemented in the two event generation frameworks Pythia and Sherpa, illustrate the improved precision of the new formalism.
description: 11 pages, 4 figures
On problems equivalent to (min,+)-convolution
Creators: name: Cygan, Marek
name: Mucha, Marcin
name: Węgrzycki, Karol
name: Włodarczyk, Michał
Publisher: name: arXiv
Year: 2017
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Computational Complexity (cs.CC)
subject: FOS: Computer and information sciences
subject: F.1.3; F.2

description: In recent years, significant progress has been made in explaining the apparent hardness of improving upon the naive solutions for many fundamental polynomially solvable problems. This progress has come in the form of conditional lower bounds -- reductions from a problem assumed to be hard. The hard problems include 3SUM, All-Pairs Shortest Path, SAT, Orthogonal Vectors, and others. In the $(\min,+)$-convolution problem, the goal is to compute a sequence $(c[i])^{n-1}_{i=0}$, where $c[k] = $ $\min_{i=0,\ldots,k} $ $\{a[i] $ $+$ $b[k-i]\}$, given sequences $(a[i])^{n-1}_{i=0}$ and $(b[i])_{i=0}^{n-1}$. This can easily be done in $O(n^2)$ time, but no $O(n^{2-\varepsilon})$ algorithm is known for $\varepsilon > 0$. In this paper, we undertake a systematic study of the $(\min,+)$-convolution problem as a hardness assumption. First, we establish the equivalence of this problem to a group of other problems, including variants of the classic knapsack problem and problems related to subadditive sequences. The $(\min,+)$-convolution problem has been used as a building block in algorithms for many problems, notably problems in stringology. It has also appeared as an ad hoc hardness assumption. Second, we investigate some of these connections and provide new reductions and other results. We also explain why replacing this assumption with the SETH might not be possible for some problems.
description: Extended abstract published in the proceedings of ICALP 2017. Full version published in TALG 2019
MPEC 2023-P76 : 2023 PJ1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 PJ1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Le cosaque et le kobzar : la peinture historique ukrainienne et la question du biais narratif
Creators: name: DZIUB, Nikol
Publisher: name: Zenodo
Year: 2024

description: Proposition de communicationColloque« Peinture d’histoire, peinture à histoires ?Procédés narratifs dans la peinture européenne du XIXe s. »(Paris, 13-14 juin 2024)

 

 

Paper proposalConference"Narrative Processes in Nineteenth-Century European Painting".(Paris, 13-14 June 2024)

 

Part of the “Gender and Nation in the Biographical Interpretations of Lesya Ukrainka’s Life and Works: Ukraine-Russian Empire-USSR, 1898-2022” Project (Departement Geschichte, Bereich Osteuropäische Geschichte, University of Basel, SNSF Postdoctoral fellowship)
A framework for total productivity measurement of construction projects.
Creators: Ayele, Selam
Fayek, Aminah Robinson
Publisher: name: University of Alberta Library
Year: 2019

Productivity measurement is a concern for both construction practitioners and researchers. In construction, productivity can be measured at three levels: activity, project, and industry. At the project level, previous studies focused on measuring the productivity of specific activities. In addition, existing project-level productivity metrics do not consider the effect of all resources used in a project. To effectively assess overall project performance, the productivity of all project activities and resources used must be taken into account. This study presents a framework that takes into consideration all resources used in a project and proposes a metric for measuring the total productivity of construction projects. A focus group session with experts, followed by questionnaire surveys, were used to assess the applicability of the framework. This paper makes a contribution by providing researchers and practitioners with a framework and tools for data collection and analysis of total construction project productivity.
Sequential state discrimination with quantum correlation
Creators: name: Zhang, Jin-Hua
name: Zhang, Fu-Lin
name: Liang, Mai-Lin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The sequential unambiguous state discrimination (SSD) of two states prepared in arbitrary prior probabilities is studied, and compared with three strategies that allow classical communication. The deviation from equal probabilities contributes to the success in all the tasks considered. When one considers at least one of the parties succeeds, the protocol with probabilistic cloning is superior to others, which is not observed in the special case with equal prior probabilities. We also investigate the roles of quantum correlations in SSD, and show that the procedure requires discords but rejects entanglement. The left and right discords correspond to the part of information extracted by the first observer and the part left to his successor respectively. Their relative difference is extended by the imbalance of prior probabilities.
description: 16pages, 6figs. We have corrected a mistake in Eq. (7a)
Epidemic Spreading on Activity-Driven Networks with Attractiveness
Creators: name: Pozzana, Iacopo
name: Sun, Kaiyuan
name: Perra, Nicola
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We study SIS epidemic spreading processes unfolding on a recent generalisation of the activity-driven modelling framework. In this model of time-varying networks each node is described by two variables: activity and attractiveness. The first, describes the propensity to form connections. The second, defines the propensity to attract them. We derive analytically the epidemic threshold considering the timescale driving the evolution of contacts and the contagion as comparable. The solutions are general and hold for any joint distribution of activity and attractiveness. The theoretical picture is confirmed via large-scale numerical simulations performed considering heterogeneous distributions and different correlations between the two variables. We find that heterogeneous distributions of attractiveness alter the contagion process. In particular, in case of uncorrelated and positive correlations between the two variables, heterogeneous attractiveness facilitates the spreading. On the contrary, negative correlations between activity and attractiveness hamper the spreading. The results presented contribute to the understanding of the dynamical properties of time-varying networks and their effects on contagion phenomena unfolding on their fabric.
Triple collinear emissions in parton showers
Creators: name: Höche, Stefan
name: Prestel, Stefan
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A framework to include triple collinear splitting functions into parton showers is presented, and the implementation of flavor-changing NLO splitting kernels is discussed as a first application. The correspondence between the Monte-Carlo integration and the analytic computation of NLO DGLAP evolution kernels is made explicit for both timelike and spacelike parton evolution. Numerical simulation results are obtained with two independent implementations of the new algorithm, using the two independent event generation frameworks Pythia and Sherpa.
description: 21 pages, 6 figures