cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: 01 - Zwischen den Stühlen
Creators: name: Bogner, Katrin
name: Wahl, Theresa
Publisher: name: Universitätsklinikum
Year: 2024
Subjects: subject: Stuhl
subject: Stuhlspende
subject: FRESCO
subject: Stuhltransplantation
subject: Medizin
subject: Gesundheit
subject: Universitätsklinikum Jena
subject: Uniklinik Jena
subject: UKJ
subject: Pharmazie
subject: Apotheke
subject: Gastro
subject: Innere Medizin
subject: Colitis Ulcerosa
subject: CED
subject: Kot-Kapsel
subject: Studie
subject: Medikament
subject: Darm
subject: Endoskopie
subject: 610

description: Es geht um Stuhlspende. Stuhl kann man spenden – und transplantieren. Und das kann sogar ähnlich wertvoll sein wie eine Blutspende! Am UKJ haben die Experten eine besondere Form entwickelt, um den gespendeten Stuhl auf Patientinnen und Patienten zu übertragen. Darüber sprechen Professor Andreas Stallmach, Direktor der Klinik für Innere Medizin IV. Und Professor Michael Hartmann, Leiter der Klinikumsapotheke. Weitere Informationen zur FRESCO-Studie: https://www.uniklinikum-jena.de/kim4/Forschung/Forschungsschwerpunkte/FRESCO.html
description: REZEPTFREI – Die UKJ-Erklärsprechstunde
ความสอดคล้องภายใน และความเที่ยงระหว่างผู้ประเมินของเครื่องมือทดสอบการทำงานของแขนและมือข้างอ่อนแรงในผู้พิการอัมพาตครึ่งซีก ฉบับภาษาไทย
Creators: name: เพียงรวี ปิงเมือง, พิศักดิ์ ชินชัย, จนัญญา ปัญญามี ทิพย์พยอม
Publisher: name: ราชวิทยาลัยแพทย์เวชศาสตร์ฟื้นฟู แห่งประเทศไทย
Year: 2559
Subjects: การเคลื่อนไหวของแขนและมือ, โรคหลอดเลือดสมอง, การทำงานของมือ

description: 2, 26, เวชศาสตร์ฟื้นฟูสาร
I Hate the News July 9
Creators: name: Dasgupta, Sunil
Publisher: name: I Hate Politics Podcast
Year: 2024
Subjects: I Hate Politics

description: Listen to this episode from I Hate Politics Podcast on Spotify. The weekly news analysis from I Hate Politics: What do the responses to a new community survey from MCPS tell us? Harford County, MD, withdraws an AP African American studies course. A crowded field of candidates seeks to replace former Prince George’s County Councilmember Mel Franklin; illegal fireworks destroys Aspen Hill home; he really short water boil advisory in DC and Arlington; a glut on pianos on local listservs and Buy Nothing groups. And more. Music from Silver Spring band Airport 77s.
Modelling the Impacts of Sea Level Rise on Suitable Dunlin Habitat in the Fraser River Delta
Creators: name: Chapman, Melanie
name: Cheng, Jingyi
name: Mancer, Jonathan
name: Hernandez, Rennier
Publisher: name: The University of British Columbia
Year: 2020

description: The Fraser River Estuary Important Bird Area is located in the Fraser River Delta region of southwestern British Columbia and encompasses Boundary Bay, Sturgeon Bank and Roberts Bank. This area is a highly productive stopover site for migratory shorebirds, and maintains hundreds of thousands of shorebirds each year, such as Dunlin ( Calidris alpina ), Western Sandpiper ( Calidris mauri ), and Black-bellied Plover ( Pluvialis squatarola ). For this reason, it is currently designated as a Western Hemisphere Shorebird Reserve Network site. The estuary’s ability to support high volumes of shorebirds is being put at increasing risk due to rising sea levels and climate change. Our study explored the effects sea level rise has on suitable Dunlin habitat through a combination of field site visits, an extensive literature review, and through the analysis of existing spatial Geographic Information Systems data. Using this information, we constructed spatial models to evaluate the distribution of suitable coastal and inland Dunlin shorebird habitat under different sea level rise scenarios. The results show that Dunlin inland habitat area decreased up to 20.12% and coastal Dunlin habitat area decreased up to 15.51%. Boundary Bay and Sturgeon Bank appear to suffer the largest amount of habitat loss, which could put the local Dunlin population under increased stress. Furthermore, we analyzed the impacts of current sea level rise adaptation strategies on the Dunlin and provided recommendations for bird-friendly adaptation strategies. The results of this model were linked to existing Pacific Flyway conservation strategies to provide recommendations for future management strategies related to the conservation of the Fraser River Delta’s ecosystem integrity and shorebird ecology.
Understanding the mechanism and cost of bacteriophage resistance in the Enterobacteriaceae
Creators: name: Gannon, Lucy
Publisher: name: University of Leicester
Year: 2022
Subjects: Uncategorized

description: Bacteriophages are viruses able to kill bacteria, forcing bacteria to adapt to survive phage attack and helping drive microbial evolution. Little is known about specificity of the interactions or how phages shape bacterial ecological traits. The aim of this thesis is to investigate how Enterobacteriacae gain resistance to bacteriophage infection, and to evaluate how different bacteriophages predating on a bacterial species can alter adaptation mechanisms utilised by the bacteria. It is known that multiple bacteriophage families can infect the same bacterial species, but how different bacterial species respond to these different phages is poorly understood. The adaptations that occur in different species of bacteria within the Enterobacteriacae when exposed to the same bacteriophage species was compared. A diverse panel of six bacteriophage species was used to create a collection of 123 phage resistant mutants in E. coli and 20 in Salmonella enterica Typhimurium. The costs of resistance in the bacteria were measured, with no fitness cost as well as decreased or increased fitness observed. Putative genes involved in bacteriophage resistance were identified by whole genome sequencing and identification of SNPs and INDELs, with 118 genes found to contain mutations. Using gene knock-out mutants, the contribution of individual genes to phage resistance was evaluated for 18 genes. Only three of these genes (btuB, sdaC, dcrB) could be confirmed to confer a phage resistance phenotype. Furthermore, fhuA which was one of the most commonly mutated genes, did not confer phage resistance when gene knockouts were created. The results demonstrate the complexity in understanding phage resistance mechanisms.
Recurrent Breast Lesion in a Patient with Systemic Lupus Erythematosus â A radiological review and case report
Creators: name: De Sousa Guerreiro, Helena Isabel
Publisher: name: EURORAD
Year: 2016
Subjects: subject: Breast
subject: MR
subject: Mammography
subject: Ultrasound
subject: Education
subject: Inflammation

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: female, 42 years
description: Clinical History: A 42-year old female with SLE presented bilateral painless breast lumps. The patient refused a core needle biopsy and a bilateral surgical excision was thus performed. In the 18 month follow up she presented with a recurrent lump on the right side. A mamm... Final Diagnosis: Lupus mastopathy with fibrosing mastitis, fat necrosis and secondary calcification.
title: 02 - Time is brain
Creators: name: Bogner, Katrin
name: Wahl, Theresa
Publisher: name: Universitätsklinikum
Year: 2024
Subjects: subject: Schlaganfall
subject: Stroke
subject: BE FAST
subject: FAST
subject: Stroke Unit
subject: SATELIT
subject: Telemedizin
subject: Schlaganfallzentrum
subject: Neurologie
subject: Medizin
subject: Gesundheit
subject: Universitätsklinikum Jena
subject: Uniklinik Jena
subject: UKJ
subject: Gehirn
subject: Schlag
subject: Notfall
subject: 610

description: Ein Schlaganfall ist immer ein akuter Notfall und sollte schnellstmöglich behandelt werden – und zwar egal, wo man sich befindet. Etwa 10.000 Menschen erleiden jährlich in Thüringen einen Schlaganfall. Woran man ihn erkennt und wie er behandelt werden kann, darüber sprechen die beiden Schlaganfallexperten der Klinik für Neurologie, Dr. Caroline Klingner und Professor Carsten Klingner.
description: REZEPTFREI – Die UKJ-Erklärsprechstunde
title: How Do They Feel?: Measuring Emotional Brand Image with User-Generated Twitter-Data Containing Emojis
Creators: name: Holthoff, Lisa
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2025
Subjects: subject: Marketing
subject: FOS: Economics and business
subject: Verbraucherverhalten
subject: Social Media
subject: Gefühlsreaktion
subject: Markenimage
subject: Maschinelles Lernen
subject: 004
subject: 150
subject: 330

description: Consumers increasingly generate content on social media platforms like Twitter by expressing and discussing their feelings and attitudes, often by using emojis. Brands can take advantage of this vast amount of free and instantly available data by conducting sentiment analyses to monitor their image and to observe consumers’ immediate emotional reactions to marketing activities or brand-related incidents. Until now, emojis were mostly ignored in these analyses. An online experiment with 1,765 participants indicates that an inclusion of emojis can improve the correct emotional interpretation of brand-related tweets (study 1). A comparison of six different sentiment analysis tools then identifies the tools that are most suitable to analyze the polarity as well as the emotional category of brand-related tweets containing emojis (study 2). Study 3 describes the development of an emoji lexicon for sentiment analyses based on a qualitative study (3a) with 1,157 participants and a quantitative study (3b) with 1,926 participants. Study 4 confirms the hypothesis that an inclusion of emojis translated with the lexicon leads to a significantly higher number of correctly classified tweets with respect to valence as well as emotion category in automated sentiment analyses of brand-related tweets. Then. by combining the tools identified in study 2 and the lexicon developed in study 3, sentiment values for 14 different global brands from four product categories are determined by analyzing 6,053,288 user-generated tweets (study 5). The results show that an inclusion of emojis in the sentiment analysis of brand-related tweets is more important for hedonic than utilitarian product categories. Finally, a management tool to continuously monitor mood towards a brand with social media data is developed. The reliability of the presented method is verified with an exemplary comparison of peaks and troughs in the measured sentiment values to brand-related incidents from the evaluation period.
Soya, soya isoflavones and health effects
Creators: name: Mörixbauer, Angela
Publisher: name: Zenodo
Year: 2022
Subjects: Soy
Legumes

description: Soya foods are very popular not only in Asia but now also in Europe and the USA – not least because of the trend towards vegan and vegetarian diets as well as for sustainability reasons to reduce meat consumption. Soya products are versatile in the kitchen and enrich a plant-based diet due to their high nutrient density and biological value of the protein. In particular, the high phytestrogen content has a number of health-promoting effects [1–3]. At the same time, however, it is precisely this content that makes people feel unsure since the opposite is often claimed on the internet and in social media, as it is shown in the review of over 500 prints, online and social media clippings in the period from October to December 2018 [4]. In particular, feminisation in men, reduced fertility, breast cancer-promoting properties and adverse effects on thyroid function are concerns. However, the current scientific literature does not confirm this but rather points to the positive health effects of soya foods and ingredients.
Supplementary document for Optimization of laser stabilization via self-injection locking to a whispering-gallery-mode microresonator: experimental study - 6184113.pdf
Creators: name: Shitikov, Artem
name: Lykov, Ilya
name: Benderov, Oleg
name: Chermoshentsev, Dmitry
name: Gorelov, Ilya
name: Danilin, Andrey
name: Galiev, Ramzil
name: Kondratyev, Nikita
name: CORDETTE, Steevy
name: Rodin, Alexander
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary materials
Apports des formations agricoles aux agriculteurs au maroc : cas de l'Office Nationale du Conseil Agricole
Creators: name: ABOUELFIDA OUMAIMA
name: ZAHRANE TARIK
Publisher: name: Zenodo
Year: 2024

description: Ce présent article a pour objet de mettre en vedette les apports qu'offrent les structures d'accompagnement mises en place par l'Office Nationale du Conseil Agricole (ONCA) de la Région Marrakech-Safi notamment les formations destinées aux agriculteurs traditionnels marocains.

Le Maroc a connu une montée de l'intérêt octroyé au secteur agricole, qui se concrétise par la mise en place des mesures étatiques pour accompagner les jeunes afin de concrétiser leurs projets entrepreneuriaux, et cela en vue de renforcer harmonieusement les plans agricoles marocains piliers notamment "Plan Maroc vert".

L'accompagnement des entreprises opérant dans le milieu agricole fait l'objet de divers dispositifs mis en place par l'Office Nationale du Conseil Agricole comme étant non seulement un centre d'incubation, de formation, de coaching et de conseil adapté et d'accompagnement des projets entrepreneuriaux locaux focalisés sur les besoins du territoire, mais aussi une structure moderne assurant une meilleure attractivité des jeunes entrepreneurs et des organisations agricoles entrepreneuriales.

Cet article visera non seulement à mettre en exergue ces actions d'accompagnement, mais aussi à montrer l'intérêt qu'elles offrent aux agriculteurs traditionnels désirant opérés sur le marché agricole marocain. Ce travail fera l'objet d'une étude qualitative basée sur des entretiens semi-directifs et aura pour objet l'analyse des apports des structures d'accompagnement et leur capacité d’offrir une acculturation agro-entrepreneuriale aux agriculteurs traditionnels.
New Teachers Union Prez Says Budget Transparency Can Blunt Cuts
Creators: name: Dasgupta, Sunil
name: Stein, David
Publisher: name: I Hate Politics Podcast
Year: 2024
Subjects: I Hate Politics

description: Listen to this episode from I Hate Politics Podcast on Spotify. After a tumultuous few years, Montgomery County Public Schools is going through big leadership changes and the general elections in November may bring more. Among them is the new president of the teachers’ union, MCEA: David Stein, a veteran math and statistics teacher in Montgomery Blair High School’s famed STEM program. Sunil Dasgupta talks with Stein about how he sees the challenges ahead for MCPS and for public education. Music by Alexandria alt-rock band Jackie and the Treehorns.
title: 03 - Das muss Frau nicht aushalten
Creators: name: Bogner, Katrin
name: Wahl, Theresa
Publisher: name: Universitätsklinikum
Year: 2024
Subjects: subject: Endometriose
subject: Gynäkologie
subject: Regelblutung
subject: Frau
subject: Frauengesundheit
subject: Menstruation
subject: Periode
subject: Gebärmutter
subject: Kinderwunsch
subject: Schmerzen
subject: Frauenklinik
subject: Blutung
subject: Universitätsklinikum Jena
subject: Uniklinik Jena
subject: UKJ
subject: Schwangerschaft
subject: 610

description: Etwa jede zehnte Frau im gebärfähigen Alter ist von Endometriose betroffen. Bei der Erkrankung breitet sich Gebärmutter-Schleimhaut außerhalb der Gebärmutterhöhle aus und verursacht derart heftige Schmerzen während der Menstruation, dass Betroffene im Alltag häufig deutlich eingeschränkt sind. Hinzu kommt: Oft dauert es Jahre bis zur Diagnose. Glücklicherweise tritt die Erkrankung immer mehr ins öffentliche Bewusstsein, sodass sich hier viel getan hat. Wie sich die Lebensqualität von betroffenen Frauen verbessern kann und welche Behandlungsmöglichkeiten es gibt, darüber sprechen Dr. Valentina Auletta und Dr. Anke Esber. Die beiden sind Oberärztinnen in der Frauenklinik und verantwortlich für die Endometriosesprechstunde am UKJ.
description: REZEPTFREI – Die UKJ-Erklärsprechstunde
ผลการฟื้นฟูสมรรถภาพของการใช้งานรยางค์บนและล่างในผู้ป่วยโรคหลอดเลือดสมองระยะกึ่งเฉียบพลันและระยะเรื้อรัง ณ รพ.รามาธิบดี
Creators: name: นวรัชต์ อุตรารัขต์กิจ, นัดดา รีชีวะ, พรรณเพชร ศิริรัตน์, พิธากร ธำรงเลาหะพันธุ์, วารี จิรอดิศัย
Publisher: name: ราชวิทยาลัยแพทย์เวชศาสตร์ฟื้นฟู แห่งประเทศไทย
Year: 2559
Subjects: สมรรถภาพการใช้งาน, โรคหลอดเลือดสมองหลังระยะเฉียบพลัน, การฟื้นฟูสภาพแบบผู้ป่วยนอก

description: 2, 26, เวชศาสตร์ฟื้นฟูสาร
Franco-Saxon Manuscript Illumination and Networks of Production in Ninth-Century Francia
Creators: name: Henderson, Emilia T.
Publisher: name: University of Leicester
Year: 2022
Subjects: Uncategorized

description: The so-called Franco-Saxon style is a category of Carolingian manuscript art that flourished particularly in the third quarter of the ninth century and is mainly associated with the monasteries of Saint-Amand, Saint-Vaast, and Saint-Bertin in north-eastern Francia. Although several famous illuminated manuscripts of the later Carolingian period are decorated in the Franco-Saxon style, it has been underserved in Carolingian art history. The most thorough survey, published in 2009, maintained the theoretical paradigm and categorisation of scholars of the first half of the twentieth century. This paradigm conceptualised the style as a uniformly developing, narrowly localised “school”, and restricted the corpus of manuscripts to examples from only three main centres, and only high-grade biblical or liturgical manuscripts comparable to the most famous examples of the style. This thesis contributes to a more holistic conceptualisation of the Franco-Saxon style. It re-assesses the ambiguous and subjective criteria of the established definition of the style by close analysis of what is demonstrably characteristic about the execution of Franco-Saxon features. Moreover, it moves away from the restrictions of the earlier paradigm, instead applying current approaches that more fully account for the surviving evidence. Motivated by the growing recognition of the role of, potentially itinerant, specialist artists and scribes in the Carolingian period, a network-informed approach is used. This allows for the identification of manuscripts that seemingly resulted from complex and interconnected production processes. Several such 'networked productions' of relevance to the Franco-Saxon style are discussed, some of which not previously properly acknowledged as Franco-Saxon. The manuscripts identified in this thesis as deserving of recognition as Franco-Saxon manuscripts help shed new light on the breadth and reach that the Franco-Saxon style attained — sometimes even outside the north-eastern Frankish area.
ความชุกของภาวะหลอดเลือดแดงส่วนปลายตีบตันที่ไม่มีอาการในผู้เป็นเบาหวานที่มารับบริการ ณ โรงพยาบาลศิริราช
Creators: name: สุพักตรา เจษฎาภัทรกุล, นวพร ชัชวาลพาณิชย์
Publisher: name: ราชวิทยาลัยแพทย์เวชศาสตร์ฟื้นฟู แห่งประเทศไทย
Year: 2559
Subjects: ความชุก, เบาหวาน, ภาวะหลอดเลือดแดงส่วนปลายตีบตันที่ไม่มีอาการ, ปัจจัยเสี่ยง

description: 2, 26, เวชศาสตร์ฟื้นฟูสาร
ผลการฝึกออกกำลังกายด้วยเพลงลีลาศจังหวะบีกินต่อสมรรถภาพการทรงตัวและการเดินในผู้สูงอายุไทยที่มีประวัติหกล้ม
Creators: name: ปภาวดี สุนทรธัย, ฐิติพร ภักดีพิบูลย์, นพวรรณ แสนเจริญสุทธิกุล, รุ่งทิพย์ สินิทธานนท
Publisher: name: ราชวิทยาลัยแพทย์เวชศาสตร์ฟื้นฟู แห่งประเทศไทย
Year: 2559
Subjects: ลีลาศจังหวะบีกิน, การฝึกทรงตัว, ผู้สูงอายุ, หกล้ม

description: 2, 26, เวชศาสตร์ฟื้นฟูสาร
การศึกษาความชุกทางเดินปัสสาวะติดเชื้อในผู้ที่ไขสันหลังบาดเจ็บเรื้อรังและใช้หลอดสวนซิลิโคนชนิดใช้ซ้ำด้วยเทคนิคสะอาด
Creators: name: คุณธัญญ์ เหล่าไพโรจน์, อภิชนา โฆวินทะ
Publisher: name: ราชวิทยาลัยแพทย์เวชศาสตร์ฟื้นฟู แห่งประเทศไทย
Year: 2559
Subjects: หลอดสวนซิลิโคนชนิดใช้ซ้ำ, การสวนปัสสาวะด้วยเทคนิคสะอาดด้วยตนเอง, บาดเจ็บไขสันหลัง, ทางเดินปัสสาวะติดเชื้อ, ความชุก

description: 2, 26, เวชศาสตร์ฟื้นฟูสาร
MPEC 2024-P96 : 2024 PC2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 PC2

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: 04 - Selten und bösartig
Creators: name: Bogner, Katrin
name: Wahl, Theresa
name: Weschenfelder, Wolfram
name: Spiegel, Christian
Publisher: name: Universitätsklinikum
Year: 2024
Subjects: subject: Sarkom
subject: Knochenkrebs
subject: Weichteilkrebs
subject: GIST
subject: selten
subject: Krebs
subject: SarkomCentrum
subject: Mitteldeutsches Krebszentrum
subject: Medizin
subject: Gesundheit
subject: Universitätsklinikum Jena
subject: Uniklinik Jena
subject: UKJ
subject: 610

description: Sarkome sind Tumoren des Knochens oder der Weichteile. Sie können nahezu überall im Körper auftreten. Allerdings sind sie sehr selten: Bei Kindern machen sie etwa zehn Prozent aller Krebserkrankungen aus, bei Erwachsenen etwa ein Prozent. Daher ist es auch so wichtig, sich im Fall der Fälle in ein einem spezialisierten Zentrum behandeln zu lassen. Dr. Wolfram Weschenfelder und Dr. Christian Spiegel, Oberärzte in der Klinik für Unfall-, Hand- und Wiederherstellungschirurgie, leiten am UKJ das SarkomCentrum. Sie sprechen über Diagnose- und Behandlungsmöglichkeiten am SarkomCentrum Jena. Weitere Informationen: https://www.uniklinikum-jena.de/tz/Kompetenzzentren/SarkomCentrum+Jena.html
description: REZEPTFREI – Die UKJ-Erklärsprechstunde
Testing particle acceleration in blazar jets with continuous high-cadence optical polarization observations
Creators: name: Liodakis, Ioannis
name: Kiehlmann, Sebastian
name: Marscher, Alan P.
name: Zhang, Haocheng
name: Blinov, Dmitry
name: Et Al
Publisher: name: EDP
Year: 2024

description: Authors- Ioannis Liodakis, Sebastian Kiehlmann, Alan P. Marscher, Haocheng Zhang, Dmitry Blinov, Svetlana G. Jorstad, Iván Agudo, Erika Benítez, Andrei Berdyugin, Giacomo Bonnoli, Carolina Casadio, Chien-Ting Chen, Wen-Ping Chen,Steven R. Ehlert, Juan Escudero, Tatiana S. Grishina, David Hiriart, Angela Hsu,Ryo Imazawa, Helen E. Jermak, Jincen Jose, Philip Kaaret, Evgenia N. Kopatskaya, Bhavana Lalchand,Elena G. Larionova, Elina Lindfors, José M. López, Callum McCall, Daria A. Morozova, Efthymios Palaiologou, Shivangi Pandey, Juri Poutanen, Suvendu Rakshit, Pablo Reig, Mahito Sasada, Sergey S. Savchenko, Elena Shablovinskaya, Sharma Neha, Manisha Shrestha, Iain A. Steele, Ivan S. Troitskiy, Yulia V. Troitskaya, Makoto Uemura, Andrey A. Vasilyev, Zachary Weaver, Klaas Wiersema, Martin C. Weisskopf
description: Variability can be the pathway to understanding the physical processes in astrophysical jets. However, the high-cadence observations required to test particle acceleration models are still missing. Here we report on the first attempt to produce continuous, $>24$ hour polarization light curves of blazars using telescopes distributed across the globe, following the rotation of the Earth, to avoid the rising Sun. Our campaign involved 16 telescopes in Asia, Europe, and North America. We observed BL Lacertae and CGRaBS J0211+1051 for a combined 685 telescope hours. We find large variations in the polarization degree and angle for both sources on sub-hour timescales as well as a $ rotation of the polarization angle in CGRaBS J0211+1051 in less than two days. We compared our high-cadence observations to particle-in-cell magnetic reconnection and turbulent plasma simulations. We find that although the state-of-the-art simulation frameworks can produce a large fraction of the polarization properties, they do not account for the entirety of the observed polarization behavior in blazar jets.
Investigating the role of EML4-ALK fusion proteins in mitotic progression of non-small cell lung cancer, and their sensitivity to anti-mitotic therapies
Creators: name: Lucken, Kellie
Publisher: name: University of Leicester
Year: 2022
Subjects: Uncategorized

description: Approximately 5-8% of non-small cell lung cancers (NSCLCs) are driven by the EML4-ALK oncogenic fusion protein. This results from a gene inversion event on chromosome 2 that creates an in-frame fusion between the N-terminal microtubule binding portion of EML4 and the C-terminal catalytic domain of the tyrosine kinase ALK. Breakpoint variation within the EML4 gene result in fusions proteins of varying lengths that markedly affect patient outcome and treatment response. Several ALK kinase inhibitors are approved for clinical use but patients develop resistance. Moreover, patients with EML4-ALK variant 3 (V3, 30% incidence) respond poorly to ALK inhibitors and have lower survival rates compared to patients with other variants, such as V1 (34% incidence). As wild-type EML4 contributes to spindle microtubule organisation and chromosome congression in mitosis, we investigated EML4-ALK fusion localisation to microtubules in mitotic cells and the impact on mitotic progression, SAC activity and cell survival. Results presented here indicate that EML4-ALK V3 protein localises to and stabilises spindle microtubules, while its expression leads to increases in mitotic defects. These include errors in chromosome congression and segregation which occur in a manner independent of ALK kinase activity. We also investigated the influence of this fusion protein on SAC integrity. We found that expression of EML4-ALK V3 led to weakened SAC activity that could be partly rescued by inhibition of ALK catalytic activity. Finally, we discovered that the NSCLC patient-derived cell line, H2228 expressing EML4-ALK V3 exhibited a synergistic response with reduced cell viability and increased apoptosis upon combination treatment with paclitaxel and ALK inhibitors. In conclusion, mitotic defects and SAC deficiency in cells expressing EML4-ALK V3 may contribute to genomic instability and render tumour cells sensitive to combination treatments of microtubule poisons and ALK inhibitors. This suggests improved personalised treatment options for lung cancer patients with unmet clinical need.
Loss of function of Vasoactive-intestinal peptide alters sex ratio and reduces male reproductive fitness in zebrafish
Creators: name: Yu, Yang
name: Tanaka, Sakura
name: Wong, Ten-Tsao
name: Zohar, Yonathan
name: Zmora, Nilli
Publisher: name: Oxford University Press
Year: 2024

description: Vasoactive-intestinal peptide (Vip) is a pleiotropic peptide with a wide range of distribution and functions. Zebrafish possess two isoforms of Vip (a and b), in which Vipa is most homologous to the mammalian form. In female zebrafish, Vipa can stimulate LH secretion from the pituitary but is not essential for female reproduction, as vipa-/- females display normal reproduction. In contrast, we have found that vipa-/- males are severely sub-fertile and sex ratio of offspring is female-biased. By analyzing all aspects of male reproduction with WT males, we show that the testes of vipa-/- are underdeveloped and contain ?70% less spermatids compared to WT counterparts. The sperm of vipa-/- males displayed reduced potency in terms of fertilization (by ?80%) and motility span and duration (by ?50%). In addition, vipa-/- male attraction to WT females was largely non-existent, indicating decreased sexual motivation. We show that vipa mRNA and protein is present in Leydig cells and in developing germ cells in the testis of WT, raising the possibility that endogenous Vipa contributes to testicular function. Absence of Vipa in vipa-/- males resulted in downregulation of three key genes in the androgen synthesis chain in the testis, 3?-hsd, 17?-hsd1 and cyp11c1 (11?-hydrogenase), associated with a pronounced decrease in 11-ketotestosterone production and, in turn, compromised reproductive fitness. Altogether, this study establishes a crucial role for Vipa in the regulation of male reproduction in zebrafish, like in mammals, with the exception that Vipa is also expressed in zebrafish testis.
title: Research Data Management in terahertz.NRW: How to ensure findability of research data even 10 years after project end
Creators: name: Externbrink, Marlen
name: Marson, Marcel
name: Winter, Nina
name: Rehwald, Stephanie
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2025
Subjects: subject: 620

description: The poster presents an overview of the research data management workflow within the terahertz.NRW network. It outlines the key steps involved in storing and processing research data, spanning from the active project phase to data publication and archiving. Particular emphasis is placed on the “Findable” aspect of the FAIR principles, showcasing measures like the enrichment of datasets with specific “terahertz metadata” to ensure the longer-term findability of research data.
description: Informationsmaterialien der Research Data Services an der Universitätsbibliothek Duisburg-Essen
title: OMERO and Data Champions in CRC 1430
Creators: name: Minges, Alexander
name: Rehwald, Stephanie
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2025
Subjects: subject: 570

description: In collaborative research centers (CRCs), sharing welldocumented data among researchers is crucial for enhancing collaborative research capabilities. The INF project aims to assist researchers in managing their data to create synergistic effects and significantly advance projects within CRC 1430. Given the dataintensive nature of these fields, proficiency in data management and documentation during collection, analysis, publication, long term storage, archiving, and reuse is essential. A key prerequisite for successful data sharing and reuse according to the FAIR principles is the creation of rich metadata, which represent the potential analysis dimensions of datasets. The INF project aids CRC members in effective research data management by providing dedicated software solutions for data handling, such as the imaging platform OMERO, the electronic lab notebook (ELN) software elabFTW, and the data repository software Dataverse.
description: Informationsmaterialien der Research Data Services an der Universitätsbibliothek Duisburg-Essen
title: 05 - Zuckersüße Babys
Creators: name: Bogner, Katrin
name: Wahl, Theresa
Publisher: name: Universitätsklinikum
Year: 2024
Subjects: subject: Baby
subject: Schwangerschaft
subject: Schwangerschaftsdiabetes
subject: Gestationsdiabetes
subject: Zucker
subject: Diabetes
subject: Insulin
subject: Geburt
subject: Geburtsmedizin
subject: Diabetologie
subject: Gesundheit
subject: Universitätsklinikum Jena
subject: Uniklinik Jena
subject: UKJ
subject: 610

description: Es gibt Frauen, die entwickeln während ihrer Schwangerschaft einen sogenannten Gestationsdiabetes. Und es gibt Frauen, die leiden schon vor ihrer Schwangerschaft an Diabetes mellitus. Egal, wie der Fall liegt: Bestens versorgt sind Schwangere dann in unserem Kompetenzzentrum „Diabetes & Schwangerschaft“. Wie genau, darüber sprechen die beiden Expertinnen Prof. Tanja Groten und PD Dr. Friederike Weschenfelder. Sie leiten das Kompetenzzentrum in der Klinik für Geburtsmedizin. Weitere Informationen: https://www.uniklinikum-jena.de/geburtsmedizin/Klinikbereiche/Kompetenzzentrum+Diabetes+_+Schwangerschaft.html
description: REZEPTFREI – Die UKJ-Erklärsprechstunde
Wiki on the Rocks – An investigation of Rock Art, Knowledge, and Authority in Wikipedia
Creators: name: Gimmerstam, Jeanette
Publisher: name: University of Leicester
Year: 2022
Subjects: Uncategorized

description: This thesis is about archaeological knowledge production on Wikipedia. Specifically, it considers who is responsible for the creation and dissemination of knowledge about rock art sites on Wikipedia, and the wider political implications of this. Wikipedia is an acknowledged resource of a general to highly specialist nature. Its role and usage have expanded hugely in recent years, yet academic consideration of its impact on the dissemination of archaeological knowledge is lacking. My focus is on Wikipedia articles about highly visited and well-known rock art World Heritage sites. This thesis will use two methodologies: Content Analysis and Critical Discourse Analysis, in order to gain a broad understanding of the content of twenty-three Wikipedia articles about rock art World Heritage sites; five case-studies will be subject to in-depth investigation. The aim of this thesis is three-fold; first, to highlight what kind of content is disseminated in the Wikipedia articles; second, who is responsible for knowledge production in the selected case studies; third, to consider the impact of how Wikipedia articles convey the nature and significance of these sites as both national and world heritage. The results demonstrate that archaeologists would benefit from being more available and accessible online to a wider audience and that archaeologists should participate in discussions and debates online in order to create qualitative knowledge and prevent fake-science.
Supplementary document for Characterization of on-chip cavity coupled emission of 2D materials at room temperature - 6184135.pdf
Creators: name: Granados-Baez, Marissa
name: MUKHERJEE, ARUNABH
name: Qiu, Liangyu
name: Chakraborty, Chitraleema
name: Vamivakas, Nickolas
name: Cardenas, Jaime
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Curves Ahead: Enhancing the Steering Law for Complex Curved Trajectories
Creators: name: Chen, Jennie J. Y.
name: Fels, Sidney S.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences
subject: H.5.2
subject: 68U35

description: The Steering Law has long been a fundamental model in predicting movement time for tasks involving navigating through constrained paths, such as in selecting sub-menu options, particularly for straight and circular arc trajectories. However, this does not reflect the complexities of real-world tasks where curvatures can vary arbitrarily, limiting its applications. This study aims to address this gap by introducing the total curvature parameter K into the equation to account for the overall curviness characteristic of a path. To validate this extension, we conducted a mouse-steering experiment on fixed-width paths with varying lengths and curviness levels. Our results demonstrate that the introduction of K significantly improves model fitness for movement time prediction over traditional models. These findings advance our understanding of movement in complex environments and support potential applications in fields like speech motor control and virtual navigation.
Analysis of a nonlinear fish-bone model for suspension bridges with rigid hangers in the presence of flow effects
Creators: name: Falocchi, Alessio
name: Webster, Justin
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Mathematics - Analysis of PDEs
Mathematics - Dynamical Systems

description: We consider a dynamic system of nonlinear partial differential equations modeling the motions of a suspension bridge. This fish-bone model captures the flexural displacements of the bridge deck's mid-line, and each chordal filament's rotation angle from the centerline. These two dynamics are strongly coupled through the effect of cable-hanger, appearing through a sublinear function. Additionally, a structural nonlinearity of Woinowsky-Krieger type is included, allowing for large displacements. Well-posedness of weak solutions is shown and long-time dynamics are studied. In particular, to force the dynamics, we invoke a non-conservative potential flow approximation which, although greatly simplified from the full multi-physics fluid-structure interaction, provides a driver for non-trivial end behaviors. We describe the conditions under which the dynamics are uniformly stable, as well as demonstrate the existence of a compact global attractor under all nonlinear and non-conservative effects. To do so, we invoke the theory of quasi-stability, first explicitly constructing an absorbing ball via stability estimates and, subsequently, demonstrating a stabilizability estimate on trajectory differences applied to the aforesaid absorbing ball. Finally, numerical simulations are performed to examine the possible end behaviors of the dynamics.
title: Editorial: Zur Einführung in das Themenheft – Geographische Bildungsprozesse im Zeitalter der Digitalität
Creators: name: Muschaweck, Isabelle
name: Pettig, Fabian
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2025
Subjects: subject: 370

description: OpenSpaces: Zeitschrift für Didaktiken der Geographie, vol. 2025, no. 0101|2025 - Sonderausgabe: Wie(so)? Geographische Bildungsprozesse im Zeitalter der Digitalität, p. 1
Electrification of the Sunshine Coast Transit System : A Feasibility Study
Creators: name: Fu, Carol
name: Lin, Jason
name: Marcus, Michelle
name: Cui, Tom
Publisher: name: The University of British Columbia
Year: 2020

description: Electrifying transportation is a necessary part of reducing greenhouse gas emissions in order to mitigate global climate change. Electric buses are gaining popularity worldwide, in urban and rural communities alike. This research, conducted in partnership with the 2 Degrees Institute, aims to explore pathways towards electrifying the transit system on the Sunshine Coast in British Columbia with the goal of implementing a fully electric fleet earlier than the current deadline of 2040. The project will employ life-cycle cost analysis to determine the most financially feasible charging method and use a numerical algorithm to optimize bus schedules in order to accommodate charging time and minimize demand charges. The report also provides recommendations for potential strategies to increase transit ridership on the Sunshine Coast based on a literature review. The results suggest that: (1) the demand charge for a fully electric fleet will be 625 kW; (2) the charging schedule can be optimized by charging 2 groups of electric buses at 2 different time periods; (3) fast charging has the lowest life-cycle cost due to smaller batteries and reduced number of chargers required; (4) strategies to increase ridership include service expansion, park-and-ride facilities, fare reduction of student and senior monthly passes and the revision of the DayPASS-on-Board program. The report findings may be used by the Sunshine Coast as well as other jurisdictions - especially rural regions - as a model for electric transit implementation.
The healthcare resource utilization and costs of chronic lung allograft dysfunction following lung transplantation in patients with commercial insurance in the United States
Creators: name: Sheshadri, Ajay
name: Sacks, Naomi C.
name: Healey, Bridget
name: Cyr, Phil
name: Boerner, Gerhard
name: Huang, Howard J.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Hematology

description: Chronic lung allograft dysfunction (CLAD), a common complication of lung transplantation, is the leading cause of death for lung transplant recipients. While data on lung transplant costs are available, the impact of CLAD on healthcare resource use (HRU) and cost is not well understood. The primary objective was to quantify the HRU and costs of CLAD in the US using real-world data. A longitudinal retrospective analysis was performed of commercial claims data from the IQVIA PharMetrics Plus database for patients aged 18–64 who underwent lung transplantation between January 1, 2006 and September 30, 2018. Lung transplantation was identified using International Classification of Disease and Common Procedure Terminology procedure codes. Patients studied were observable for at least 12 months before and after transplantation. Patients who developed CLAD were identified using novel, diagnosis codes for incident lung disease at least one year following transplantation. Descriptive analyses were conducted to assess the study’s outcomes prior to and following a CLAD diagnosis. All-cause HRU and costs, the study’s primary outcomes, leading up to and following CLAD diagnosis were calculated. Among 129 transplant patients who developed CLAD, healthcare costs were substantially higher in the year following diagnosis ($198,113), compared to the year leading to diagnosis ($85,276). Inpatient admissions were responsible for most costs in years 1 and 2 following diagnosis ($99,372 and $83,348 respectively). Drug costs were higher in the 12 months post-index, compared to the 12 months pre-index ($3,600 vs $2,527). Claims data do not include clinical data, have limits determining loss of follow-up, and do not provide granularity to determine disease severity. Also, there is no ICD-10-CM code specific to CLAD or BOS. CLAD after lung transplant is associated with substantial HRU and costs. Further work is needed to develop interventions that reduce this impact.
Practical Implications of Implementing Local Differential Privacy for Smart grids
Creators: name: Hafeez, Khadija
name: Rehmani, Mubashir Husain
name: Mishra, Sumita
name: OShea, Donna
Publisher: name: arXiv
Year: 2025
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Recent smart grid advancements enable near-realtime reporting of electricity consumption, raising concerns about consumer privacy. Differential privacy (DP) has emerged as a viable privacy solution, where a calculated amount of noise is added to the data by a trusted third party, or individual users perturb their information locally, and only send the randomized data to an aggregator for analysis safeguarding users and aggregators privacy. However, the practical implementation of a Local DP-based (LDP) privacy model for smart grids has its own challenges. In this paper, we discuss the challenges of implementing an LDP-based model for smart grids. We compare existing LDP mechanisms in smart grids for privacy preservation of numerical data and discuss different methods for selecting privacy parameters in the existing literature, their limitations and the non-existence of an optimal method for selecting the privacy parameters. We also discuss the challenges of translating theoretical models of LDP into a practical setting for smart grids for different utility functions, the impact of the size of data set on privacy and accuracy, and vulnerability of LDP-based smart grids to manipulation attacks. Finally, we discuss future directions in research for better practical applications in LDP based models for smart grids.
description: 7 pages, 5 figures, 1 table
title: 06 - Wann bin ich (k)ein Notfall?
Creators: name: Bogner, Katrin
name: Wahl, Theresa
Publisher: name: Universitätsklinikum
Year: 2024
Subjects: subject: Notfall
subject: Ambulanz
subject: Notaufnahme
subject: ZNA
subject: 112
subject: Rettungsdienst
subject: Rettungswagen
subject: Notfallmedizin
subject: Gesundheit
subject: Universitätsklinikum Jena
subject: Uniklinik Jena
subject: UKJ
subject: 610

description: Überfüllte Wartezimmer, lange Wartezeiten, zu wenig Personal – das ist das Bild, das viele von der Notaufnahme haben. Ob dieser Eindruck stimmt oder was die Gründe dafür sind, darüber sprechen Dr. Jan-Christoph Lewejohann, Leiter der Notaufnahme des UKJ, und Stefanie Hemmer, Oberärztin in der Notaufnahme. Weitere Informationen: https://www.uniklinikum-jena.de/zna/Zentrale+Notaufnahme.html
description: REZEPTFREI – Die UKJ-Erklärsprechstunde
title: Digital Place-making?: Der Transcampus als digitaler Lern- und Interaktionsraum in der universitären Geographielehrer*innenbildung
Creators: name: Falk, Leon
name: Jahnke, Holger
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2025
Subjects: subject: digitalization
subject: online teaching
subject: geography teacher education
subject: Place-making
subject: Digitalisierung
subject: Online-Lehre
subject: Geographielehrer*innenbildung
subject: 370

description: During the coronavirus pandemic, the "Transcampus" was developed as a digital place of learning and interaction. It is based on a padlet map, which is produced and shaped by the student participants, and over the course of the semester gradually became a place of experience on its own. Building on conceptual thoughts on place and place-making, preliminary considerations on the possibilities of digital place-making and the emotional attachment to digitally based teaching-learning platforms are presented.
description: Während der Corona-Pandemie wurde der „Transcampus“ als digitaler Lern- und Interaktionsort entwickelt. Er basiert auf einer Padlet-Map, welche durch die Teilnehmenden selbst gestaltet wird und im Laufe des Semesters sukzessive zu einem eigenen Erfahrungsort wurde. Aufbauend auf konzeptionellen Gedanken zu place und place-making werden grundlegende Überlegungen zu den Möglichkeiten des digital place-making und der emotionalen Bindung an digital basierte Lehr-Lern-Plattformen vorgestellt.
description: OpenSpaces: Zeitschrift für Didaktiken der Geographie, vol. 2025, no. 0101|2025 - Sonderausgabe: Wie(so)? Geographische Bildungsprozesse im Zeitalter der Digitalität, p. 16
title: Jugendpartizipation für eine inklusive digitale Mobilitätswende: Die Perspektive von Lehrkräften und außerschulischen Multiplikator*innen in Hannover und Hamburg
Creators: name: Koch, Jonas
name: Hove, Tomke
name: Meyer, Christiane
Publisher: name: DuEPublico: Duisburg-Essen Publications online, University of Duisburg-Essen, Germany
Year: 2025
Subjects: subject: digital media skills
subject: teacher training education
subject: didactics of geography
subject: Mobilitätsbildung
subject: Bildung für nachhaltige Entwicklung (BNE)
subject: Change Agents
subject: Partizipation
subject: Smart Mobility
subject: 370

description: Smart Mobility zur Umsetzung der digitalen Mobilitätswende ist ein zentraler Ansatzpunkt zur Erreichung der Klimaschutzziele im Verkehrssektor. Um eine inklusive Mobilitätswende im Sinne der Agenda 2030 zu realisieren, sollten insbesondere Jugendliche für die sozialen Implikationen der digitalen Mobilitätswende sensibilisiert werden. Bildung für nachhaltige Entwicklung (BNE), in deren Rahmen Lehrkräfte und außerschulische Multiplikator*innen als Change Agents agieren, spielt dabei eine zentrale Rolle. Ziel des präsentierten Forschungsprojekts ist es, die Perspektiven von Lehrkräften und außerschulischen Multiplikator*innen auf die Partizipation von Jugendlichen bei der Realisierung der digitalen Mobilitätswende zu ermitteln. Dafür wurden 19 Interviews mit Lehrkräften und Multiplikator*innen aus Hannover und Hamburg durchgeführt. Die Ergebnisse zeigen, dass die Partizipation von Schüler*innen bei der Entwicklung von Smart-Mobility-Angeboten als zentral erachtet wird. Schule gilt dabei als wichtiger Ort, um für die sozialen Aspekte von (digitaler) Mobilität zu sensibilisieren und Schüler*innen auf mögliche Partizipationsformate vorzubereiten. Außerschulische und schulische Lernangeboten sollten dafür stärker verknüpft werden.
description: Smart mobility solutions are seen as essential for achieving climate protection goals in the transport sector. In order to achieve an inclusive mobility transition in line with the 2030 Agenda, young people in particular should be made aware of the social implications of the digitalised mobility transition. Education for Sustainable Development (ESD), in which teachers and extracurricular multipliers act as change agents, plays a central role. The aim of the research project is to determine the perspectives of teachers and extracurricular multipliers on the participation of young people in the realisation of a digital mobility transition. As part of the study, 19 interviews were conducted with teachers and multipliers from Hannover and Hamburg. The results show that the participation of students in the development of smart mobility services is seen as a key element. Schools are therefore seen as an important place to sensitise students to the social aspects of (digital) mobility and to prepare them for participatory opportunities. To this end, extracurricular and school-based learning programmes should be more closely linked.