cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Efficacy of an online self-compassion intervention at work: A randomized controlled study
Creators: name: Igic, Ivana
name: Krieger, Tobias
name: Pang, Dandan
name: Hirschi, Andreas
Year: 2021

description: The present study investigated the effectiveness of a brief internet-based intervention to improve self-compassion (SC) among employees and tested if the intervention improves health (i.e., emotional exhaustion), motivation (i.e., work engagement), and productivity (i.e., procrastination). A sample of 100 employees participated in the randomized controlled trial including an intervention group (N = 48) and a waitlist control group with delayed access to the intervention (N = 52). Assessments were taken at baseline, after the intervention (6 weeks from the baseline), and at follow-up (12 weeks from the baseline). Mixed-model repeated-measures analysis of variance showed significant intervention effects for SC and procrastination. The intervention effects were maintained at the 6-weeks follow-up. No effects were found for emotional exhaustion and work engagement. Growth curve analyses revealed that those with unfavorable initial levels of exhaustion, work engagement, and self-efficacy benefited more from the intervention in terms of increased SC. Our findings are discussed in the context of occupational health promotion in general and SC-based interventions specifically.
Vivências de Mulheres Lésbicas no Atendimento em Saúde da Mulher na Atenção Primária de Saúde no Distrito Federal
Creators: name: Bueno, Louise
name: Alves de Oliveira, Luciane
name: Chamoschine, Marcelo
name: Soligo, Thamy
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420210
subject: Social epidemiology

description: O presente trabalho tem como objetivo geral dar visibilidade às experiências de mulheres lésbicas na busca por cuidados em saúde da mulher. Trata-se de um estudo exploratório, de caráter qualitativo, desenvolvido incluindo entrevistas presenciais com mulheres usuárias da Atenção Primária do Distrito Federal. A importância desta problematização está relacionada com a necessidade de reconhecimento das especificidades destas mulheres, e com a escassez de publicações nacionais que elucidem as dificuldades práticas enfrentadas na busca pelo cuidado em questão, embora existam formalmente programas e diretrizes que contemplem os cuidados específicos em saúde da mulher para lésbicas. As informações captadas, através de entrevistas presenciais, devem possibilitar a identificação de subsídios úteis para o aprimoramento da prática, além de facilitar o desenvolvimento de outras pesquisas quantitativas ou focalizadas relacionadas à temática.
Development of certain benzylidene coumarin derivatives as anti-prostate cancer agents targeting EGFR and PI3Kβ kinases
Creators: name: Ghany, Lina M. A. Abdel
name: Ibrahim, Tarek S.
name: Alharbi, Abdulrahman S.
name: Abdel-Aziz, Mohamed S.
name: El-labbad, Eman M.
name: Elagawany, Mohamed
name: Ryad, Noha
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Cell Biology
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Hematology

description: Novel coumarin derivatives were synthesised and tested for their cytotoxicity against human cancer cells (PC-3 and MDA-MB-231). Compounds 5, 4b, and 4a possessed potent cytotoxic activity against PC-3 cells with IC50 3.56, 8.99, and 10.22 µM, respectively. Compound 4c displayed cytotoxicity more than erlotinib in the MDA-MB-231 cells with IC50 8.5 µM. Moreover, compound 5 exhibited potent inhibitory activity on EFGR with IC50 0.1812 µM, as well as PI3Kβ inhibitory activity that was twofold higher than LY294002, suggesting that this compound has a dual EGFR and PI3Kβ inhibiting activity. Docking aligns with the in vitro results and sheds light on the molecular mechanisms underlying dual targeting. Furthermore, compound 5 decreased AKT and m-TOR expression in PC-3 cells, showing that it specifically targets these cells via the EGFR/PI3K/Akt/m-TOR signalling pathway. Simultaneously, compound 5 caused cell cycle arrest at S phase and induced activation of both intrinsic and extrinsic apoptotic pathways.
Spirogammarus major CarauSu 1943
Creators: name: Copilaș-Ciocianu, Denis
name: Palatov, Dmitry
name: Rewicz, Tomasz
name: Sands, Arthur F.
name: Arbačiauskas, Kęstutis
name: Haaren, Ton Van
name: Hebert, Paul D. N.
name: Grabowski, Michał
name: Marin, Ivan
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Gammaridae
Spirogammarus
Spirogammarus major

description: SPIROGAMMARUS MAJOR (CĂRĂUȘU, 1943) COMB. & STAT. NOV.
Chaetogammarus tenellus major CărăuȘu, 1943.
Diagnosis: Same as for genus (see above).
Remarks: Spirogammarus major can be distinguished from C. trichiatus (in parentheses) by: its larger size (16 vs. 12 mm; Fig. 5C), absence of setae on the basal segment of mandibular palp, subequal gnathopod propodi (propodus 2 longer than propodus 1), straight anterolateral head lobes (acutely produced; Fig. 6B), denser setation along the inner side of the gnathopod palm (Fig. 6C), urosomites armed with clusters of two to four spines (solitary spines; Fig. 6A), uropod 3 exopod with dense setation in both sexes (only males have dense setation; Fig. 6D), and uropod 3 endopod in males is armed with spines and long setae (setae absent in both sexes; Fig. 6D). Both taxa are similar with respect to the setosity of antennae (Fig. 7A, B) and pereopod 3 (Fig. 7D).
Distribution: Lagoons, estuaries and lower stretches of rivers that drain along the north-western to western shore of the Black Sea. Our morphomolecular analyses confirm that S. major is a widespread invasive species in European inland waters, being widely distributed along the Danube, lower Rhine, Oder and Dnieper rivers (Fig. 4).
Type locality: Lake Shabla (Shablensko Ezero), Bulgaria.
description: Published as part of Copilaș-Ciocianu, Denis, Palatov, Dmitry, Rewicz, Tomasz, Sands, Arthur F., Arbačiauskas, Kęstutis, Haaren, Ton Van, Hebert, Paul D. N., Grabowski, Michał & Marin, Ivan, 2023, A widespread Ponto-Caspian invader with a mistaken identity: integrative taxonomy elucidates the confusing taxonomy of Trichogammarus trichiatus (= Echinogammarus) (Crustacea: Amphipoda), pp. 821-846 in Zoological Journal of the Linnean Society 198 on page 833, DOI: 10.1093/zoolinnean/zlad010, http://zenodo.org/record/8152446
Chaetogammarus MARTYNOV 1924
Creators: name: Copilaș-Ciocianu, Denis
name: Palatov, Dmitry
name: Rewicz, Tomasz
name: Sands, Arthur F.
name: Arbačiauskas, Kęstutis
name: Haaren, Ton Van
name: Hebert, Paul D. N.
name: Grabowski, Michał
name: Marin, Ivan
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Gammaridae
Chaetogammarus

description: GENUS CHAETOGAMMARUS MARTYNOV, 1924
Type species: Gammarus ischnus Stebbing, 1899.
I n c l u d e d s p e c i e s: C h a e t o g a m m a r u s h y r c a n u s Pjatakova 1962, C. pauxillus (Sars, 1896), C. placidus (Sars, 1896), C. aearpachoaeskyi (Sars, 1894) and C. trichiatus Martynov, 1932.
Non-included species: Echinogammarus karadagiensis Grintsov, 2009 and E. mazestiensis Marin & Palatov, 2020 will be transferred to a new genus (I. Marin, D. Palatov, and D. CopilaȘ- Ciocianu, unpub. obs.).
Amended diagnosis: Small- to large-sized species (≤ 15 mm); females smaller than males. Head with oblique anteroventral lobe, sometimes distally produced. Eyes large, reniform, well pigmented. Body non-carinate. Antenna 1 feebly setose, accessory flagellum two- to eight-segmented; antenna 2 usually shorter that antenna 1, without calceoli, deeply setose in males and less setose in females. Lower lip (labium) with mostly reduced inner lobes. Gnathopod 1 smaller than gnathopod 2, sexually dimorphic, stronger in males, propodus generally teardrop shaped; gnathopod 2 sexually dimorphic, stronger in males, propodus trapezoidal with oblique palmar margin. Basis of pereopods 5–7 without or with weak posteroventral lobes, dominated by spines. Uropod 3 with exopod about four to six times as long as wide, generally dominated by spines. Urosomites 1 and 2 without elevations, armed with clusters of spines; urosomite 3 with a pair of submedian spines. Telson deeply cleft into suboval lobes, bearing clusters of spines distally and submedially.
Synonymized genera: Trichogammarus Hou & Sket, 2016.
Distribution: The native range of the genus is restricted to the Ponto-Caspian basin. Its species occur in the Caspian Sea at up to 500 m depth, and in lagoons, estuaries and lower stretches of rivers that drain into the Black, Azov and Caspian seas.
description: Published as part of Copilaș-Ciocianu, Denis, Palatov, Dmitry, Rewicz, Tomasz, Sands, Arthur F., Arbačiauskas, Kęstutis, Haaren, Ton Van, Hebert, Paul D. N., Grabowski, Michał & Marin, Ivan, 2023, A widespread Ponto-Caspian invader with a mistaken identity: integrative taxonomy elucidates the confusing taxonomy of Trichogammarus trichiatus (= Echinogammarus) (Crustacea: Amphipoda), pp. 821-846 in Zoological Journal of the Linnean Society 198 on pages 833-834, DOI: 10.1093/zoolinnean/zlad010, http://zenodo.org/record/8152446
Development of certain benzylidene coumarin derivatives as anti-prostate cancer agents targeting EGFR and PI3Kβ kinases
Creators: name: Elagawany, Mohamed
name: Ghany, Lina M. A. Abdel
name: Ibrahim, Tarek S.
name: Alharbi, Abdulrhman S.
name: Abdel-Aziz, Mohamed S.
name: El-labbad, Eman M.
name: Ryad, Noha
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Cell Biology
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Hematology

description: Novel coumarin derivatives were synthesised and tested for their cytotoxicity against human cancer cells (PC-3 and MDA-MB-231). Compounds 5, 4b, and 4a possessed potent cytotoxic activity against PC-3 cells with IC50 3.56, 8.99, and 10.22 µM, respectively. Compound 4c displayed cytotoxicity more than erlotinib in the MDA-MB-231 cells with IC50 8.5 µM. Moreover, compound 5 exhibited potent inhibitory activity on EFGR with IC50 0.1812 µM, as well as PI3Kβ inhibitory activity that was twofold higher than LY294002, suggesting that this compound has a dual EGFR and PI3Kβ inhibiting activity. Docking aligns with the in vitro results and sheds light on the molecular mechanisms underlying dual targeting. Furthermore, compound 5 decreased AKT and m-TOR expression in PC-3 cells, showing that it specifically targets these cells via the EGFR/PI3K/Akt/m-TOR signalling pathway. Simultaneously, compound 5 caused cell cycle arrest at S phase and induced activation of both intrinsic and extrinsic apoptotic pathways.
MOESM2 of Obesity inhibits the osteogenic differentiation of human adipose-derived stem cells
Creators: name: Strong, Amy
name: Hunter, Ryan
name: Jones, Robert
name: Bowles, Annie
name: Dutreil, Maria
name: Gaupp, Dina
name: Hayes, Daniel
name: Gimble, Jeffrey
name: Levi, Benjamin
name: McNulty, Margaret
name: Bunnell, Bruce
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Figure S2. Estradiol enhanced osteogenic differentiation of obASCs. lnASCs and obASCs were seeded on PLGA scaffolds and induced with CDS-ODM supplemented with 10 Nm estradiol. Scaffolds stained with Alizarin Red are shown. Scale bar represents 1 mm.
title: Healthy Rural Texas: Community Resource Guide
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: subject: Latino
subject: participant guide
subject: community resource
subject: recipe
subject: rural
subject: evidence-based
subject: family-focused
subject: m-health
subject: obesity
subject: prevention
subject: nutrition
subject: physical activity
subject: weight
subject: community partnership

description: Previously known as Healthy Frio, Healthy Rural Texas is a community partnership examining the delivery of a family-based program designed to counter the prevalence of obesity and obesity-related diseases in rural Latino populations in South Texas.
description: This record features a community resource guide, a comprehensive packet for participants of the Healthy Rural Texas study. The community resource guide aims to enhance participant engagement and lifestyle improvement in the context of the study. It includes exercise suggestions, family activity ideas, meal recommendations, healthy recipe suggestions, and a list of community centers and businesses to visit for healthy living.
Additional file 1: of Fluid resuscitation practice patterns in intensive care units of the USA: a cross-sectional survey of critical care physicians
Creators: name: Miller, Timothy
name: Bunke, Martin
name: Nisbet, Paul
name: Brudney, Charles
Publisher: name: Figshare
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: ICU Fluid Utilization Survey. (DOCX 308 kb)
Coping with Family Break-ups : Converging Consequences for Fathers and Mothers?
Creators: name: Kessler, Dorian
Year: 2016

description: This article examines two sources of heterogeneity in gender differentials in parents' adjustment to family break-up: variations in the domain of well-being and historical changes. With respect to domain-specificity of the consequences of divorce, it examines whether mothers, with reference to their specialization in child care and housework, suffer greater losses than fathers in adjusted household incomes as a result of divorce, as well as whether or not these inequalities are also found in subjective evaluations of financial well-being. On the downside, it analyzes whether fathers, with reference to the disadvantages they face in separation dynamics, in terms of marriage health premiums and access to social resources after divorce, suffer drops in immaterial well-being similar to those experienced by mothers. The results from bivariate regressions on five pooled, cross-sectional datasets of divorcees and entropy-balanced counterfactual samples of continuously married individuals suggest that there is no well-being domain in which divorced fathers fare relatively worse than divorced mothers. Surprisingly, fathers and mothers subjective reports of facing more diffculties than their counterfactuals in making ends meet are quite similar. Yet, unlike fathers, mothers for whom the divorce happened long ago are significantly less happy and worse off in terms of subjective health and permanent health problems than their counterfactuals. Comparisons of parents who separated before the divorce law revision in Switzerland (2000) with those that separated after it, however, suggest that the long-term disadvantages of divorced mothers might be a reflection of the higher divorce effects among older cohorts, or the higher selectivity of divorcees among these cohorts. Mothers who divorced after the turn of the millennium report levels of happiness that are more similar to the levels reported by their counterfactuals than mothers who separated before the turn of the millennium. This decrease in the happiness disadvantage of divorce for mothers cannot be explained by more equal child care arrangements or improvements in relative incomes: immediately following a divorce, mothers are still three times more likely than fathers to have children below 16 years cohabiting and they still show about 30% lower adjusted household incomes than they would if they had remained married. Judges shift towards "clean breaks" are likely to have contributed to this stability.
Challenging the Biginelli scaffold to surpass the first line antitubercular drugs: Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibition activity and molecular modelling studies
Creators: name: El-Shoukrofy, Mai S.
name: Atta, Amal
name: Fahmy, Salwa
name: Sriram, Dharmarajan
name: Shehat, Michael G.
name: Labouta, Ibrahim M.
name: Mahran, Mona A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: New Biginelli adducts were rationalised, via the introduction of selected anti-tubercular (TB) pharmacophores into the dihydropyrimidine (DHPM) ring of deoxythymidine monophosphate (dTMP), the natural substrate of Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt). Repurposing was one of the design rationale strategies for some selected mimics of the designed compounds. The anti-TB activity was screened against the Mtb H37Rv strain where 11a was superior to ethambutol (EMB), and was 9-fold more potent than pyrazinamide (PZA). Additionally, compounds 11b, 4a, 4b, 13a, 13b and 14a elicited higher anti-TB activity than PZA, showing better safety profiles than EMB against RAW 264.7 cells’ growth. The in vitro TMPKmt inhibition assay released compounds 11a, 11b and 13b as the most potent inhibitors. Docking studies presumed the binding modes and molecular dynamics (MD) simulation revealed the dynamic stability of 11a-TMPKmt complex over 100 ns. In silico prediction of the chemo-informatics properties of the most active compounds was conducted.
title: Healthy Rural Texas: Measurement
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: subject: Latino
subject: measurement
subject: metrics
subject: survey
subject: rural
subject: evidence-based
subject: family-focused
subject: m-health
subject: obesity
subject: prevention
subject: nutrition
subject: physical activity
subject: weight
subject: community partnership

description: Previously known as Healthy Frio, Healthy Rural Texas is a community partnership examining the delivery of a family-based program designed to counter the prevalence of obesity and obesity-related diseases in rural Latino populations in South Texas.
description: This record includes the survey distributed to participants in the Healthy Rural Texas study. This survey records demographics, acculturation, vitals and physical health information, food security and environment, quality of life, depression, anxiety, sleep quality, and related variables.
MOESM8 of What evidence exists for the effectiveness of on-farm conservation land management strategies for preserving ecosystem services in developing countries? A systematic map
Creators: name: Thorn, Jessica
name: Friedman, Rachel
name: Benz, David
name: Willis, Kathy
name: Petrokofsky, Gillian
Publisher: name: Figshare
Year: 2016
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 8. Agroforestry tree crops studied in articles included in the review, with scientific name with common name and uses.
Evaluation of hydrazone and N-acylhydrazone derivatives of vitamin B6 and pyridine-4-carbaldehyde as potential drugs against Alzheimer’s disease
Creators: name: Bartolić, Marija
name: Matošević, Ana
name: Maraković, Nikola
name: Bušić, Valentina
name: Roca, Sunčica
name: Vikić-Topić, Dražen
name: Sabljić, Antonio
name: Bosak, Anita
name: Gašo-Sokač, Dajana
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Cell Biology
Neuroscience
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer
Mental Health
Hematology

description: The growing prevalence of Alzheimer’s disease calls for a drug that can simultaneously act towards several targets involved in the pathophysiology of the disease. In our study, we evaluated the potential of hydrazone and N-acylhydrazone derivatives of vitamin B6 and pyridine-4-carbaldehyde to be used as multi-target directed ligands targeting cholinergic system by inhibiting acetyl- and butyrylcholinesterase, lowering the accumulation of β-amyloid plaques by inhibiting both the β-secretase activity and amyloid self-aggregation, and maintaining the biometal balance by chelating certain biometals. Our results showed that all of the tested hydrazones were potent inhibitors of human cholinesterases with inhibition constants (Ki) in micromolar range able to lower the activity of β-secretase, inhibit amyloid aggregation, chelate biometals and act as antioxidants. Also, most of them were estimated to be able to cross the blood–brain barrier by passive transport and to be absorbed in human intestines as well as with moderate metabolic stability in liver microsomes.
Additional file 13: of Elusive ditrysian phylogeny: an account of combining systematized morphology with molecular data (Lepidoptera)
Creators: name: HeikkilĂ¤, Maria
name: Mutanen, Marko
name: Wahlberg, Niklas
name: Sihvonen, Pasi
name: Kaila, Lauri
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Inorganic Chemistry
subject: Hematology
subject: Plant Biology
subject: 60506 Virology

description: Phylogenetic tree from maximum likelihood analysis of combined morphological and molecular data, 422 taxa. The data set includes all the taxa for which DNA data were available. Morphological data were available for 268 of these taxa. (PDF 28 kb)
MOESM1 of Centrosome associated genes pattern for risk sub-stratification in multiple myeloma
Creators: name: Kryukov, Fedor
name: Nemec, Pavel
name: Radova, Lenka
name: Kryukova, Elena
name: Okubote, Samuel
name: Jiri Minarik
name: Stefanikova, Zdena
name: Ludek Pour
name: Hajek, Roman
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology

description: Additional file 1. Centrosome associated gene pattern (CAGP) expression subgroups.
Lutjanus guilcheri Fourmanoir 1959
Creators: name: Swain, Ritanjali
name: Kisku, Subash
name: Nayak, Lakshman
name: Mishra, Subhrendu Sekhar
name: Patro, Shesdev
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Perciformes
Lutjanidae
Lutjanus
Lutjanus guilcheri

description: 1. Lutjanus guilcheri Fourmanoir, 1959: Yellowfin red snapper (Figure 1)
Material examined: EBEC /ZSI/F-13369, 1 ex., 216 mm SL, Gopalpur fish landing center, coll. R. Swain, 24 th November 2021.
Diagnosis: D X, 14; A III, 9; P 17; V 1, 5; LL 56; GR 7+14. Body depth 2.67 and HL 2.74 times in SL; eye diameter 4.8 and suborbital depth 4.03 times in HL; preopercular notch and knob poorly developed; vomerine tooth patch diamond shaped; tongue with a patch of granular teeth; caudal fin slightly emarginated; scales above lateral line rise obliquely. Colour: Body reddish-orange and pectoral fins reddish-orange in life.
Distribution: Indian Ocean: known from Madagascar, Sri Lanka, and the Bay of Bengal (Froece & Pauly, 2021). India – Tamil Nadu (Murugan et al., 2014), Andaman Islands (Talwar, 1990; Rajan, 2001) and Odisha (present report).
Remarks: This species was doubtfully listed from West Bengal (Talwar et al., 1992) without any material evidence (Barman, 2017) and the same was followed by subsequent authors (Das et al., 2007; Sanyal et al., 2012). This species was also not reported from southern neighboring state Andhra Pradesh. The present work confirms its occurrence from northern part of Bay of Bengal and reports as first record from Odisha coast. It may possible that the species was earlier confused with L. malabaricus or L. erythropterus, while both the species are known to occur along Odisha coast (Barman, 2017).
description: Published as part of Swain, Ritanjali, Kisku, Subash, Nayak, Lakshman, Mishra, Subhrendu Sekhar & Patro, Shesdev, 2022, First record of four snapper fishes (Perciformes: Lutjanidae) from Odisha, East coast of India, pp. 43-49 in Records of the Zoological Survey of India 122 (1) on page 44, DOI: 10.26515/rzsi/v122/i1/2022/167436, http://zenodo.org/record/10913879
Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation
Creators: name: Řehulka, Jiří
name: Jurášek, Michal
name: Dráber, Pavel
name: Ivanová, Aleksandra
name: Gurská, Soňa
name: Ječmeňová, Kateřina
name: Mokshyna, Olena
name: Hajdúch, Marián
name: Polishchuk, Pavel
name: Drašar, Pavel B.
name: Džubák, Petr
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Space Science
Medicine
Cell Biology
Pharmacology
Chemical Sciences not elsewhere classified
Cancer

description: Estradiol dimers (EDs) possess significant anticancer activity by targeting tubulin dynamics. In this study, we synthesised 12 EDs variants via copper-catalysed azide-alkyne cycloaddition (CuAAC) reaction, focusing on structural modifications within the aromatic bridge connecting two estradiol moieties. In vitro testing of these EDs revealed a marked improvement in selectivity towards cancerous cells, particularly for ED1–8. The most active compounds, ED3 (IC50 = 0.38 μM in CCRF-CEM) and ED5 (IC50 = 0.71 μM in CCRF-CEM) demonstrated cytotoxic effects superior to 2-methoxyestradiol (IC50 = 1.61 μM in CCRF-CEM) and exhibited anti-angiogenic properties in an endothelial cell tube-formation model. Cell-based experiments and in vitro assays revealed that EDs interfere with mitotic spindle assembly. Additionally, we proposed an in silico model illustrating the probable binding modes of ED3 and ED5, suggesting that dimers with a simple linker and a single substituent on the aromatic central ring possess enhanced characteristics compared to more complex dimers.
Additional file 1: Table S1. of Usefulness of the SF-36 Health Survey in screening for depressive and anxiety disorders in rheumatoid arthritis
Creators: name: Matcham, Faith
name: Norton, Sam
name: Steer, Sophia
name: Hotopf, Matthew
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Title of data â   SF36 Mental Health (MH) and Mental Component Summary (MCS) scores as predictors of pMDD, pGAD or any psycholgical disorder (pMDD or pGAD) according to PHQ9 or GAD7 criteria. Description of data â   summary of all potential thresholds identified for indicating presence of pMDD or pGAD, along with relevant sensitivity and specificity data. (DOCX 17 kb)
Additional file 2: of An exploratory pilot study to assess self-perceived changes among social assistance recipients regarding employment prospects after receiving dental treatment
Creators: name: Singhal, Sonica
name: Mamdani, Muhammad
name: Mitchell, Andrew
name: Tenenbaum, Howard
name: QuiĂąonez, Carlos
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Table. Job-seeking Skills Self-efficacy (JSS) scale. (DOCX 58Â kb)
Additional file 4: Figure S2. of High-quality draft genome sequence and description of Haemophilus massiliensis sp. nov.
Creators: name: Cheikh Lo
name: Senthil Sankar
name: BĂŠcaye Fall
name: Bissoume Sambe-Ba
name: Silman Diawara
name: Gueye, Mamadou
name: Mediannikov, Oleg
name: Blanc-Tailleur, Caroline
name: Boubacar Wade
name: Raoult, Didier
name: Pierre-Edouard Fournier
name: Fenollar, Florence
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Gel view comparing Haemophilus massiliensis strain FF7T to the members of the Haemophilus genus. The gel view displays the raw spectra of all loaded spectrum files arranged in a pseudo-gel like look. The x-axis records the m/z value. The left y-axis displays the running spectrum number originating from subsequent spectra loading. The peak intensity is expressed by a Gray scale scheme code. The color bar and the right y-axis indicate the relation between the color a peak is displayed with and the peak intensity in arbitrary units. Displayed species are indicated on the left. (DOCX 192 kb)
Additional file 1: Table S1. of Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation
Creators: name: Ben-Shian Huang
name: Muh-Hwa Yang
name: Wang, Peng-Hui
name: Hsin-Yang Li
name: Teh-Ying Chou
name: Yi-Jen Chen
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Patient characteristics. Table S2. List of proteins tested by antibodies and characteristics of the corresponding antibodies used. Table S3. IHS of pre-xenografted myoma and implanted parasitic myoma. Table S4. IHC scores of control, OVX and E2 groups. Table S5. IHC scores of control, AI, GnRHa, and SERM. (DOCX 33 kb)
Additional file 1: Table S1. of High-quality draft genome sequence and description of Haemophilus massiliensis sp. nov.
Creators: name: Cheikh Lo
name: Senthil Sankar
name: BĂŠcaye Fall
name: Bissoume Sambe-Ba
name: Silman Diawara
name: Gueye, Mamadou
name: Mediannikov, Oleg
name: Blanc-Tailleur, Caroline
name: Boubacar Wade
name: Raoult, Didier
name: Pierre-Edouard Fournier
name: Fenollar, Florence
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Antimicrobial susceptibility and minimum inhibitory concentrations (MIC) of Haemophilus massiliensis strain FF7T sp nov. (DOC 30 kb)
Additional file 3: of Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation
Creators: name: Ben-Shian Huang
name: Muh-Hwa Yang
name: Wang, Peng-Hui
name: Hsin-Yang Li
name: Teh-Ying Chou
name: Yi-Jen Chen
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Supplemental Material and Methods. Part 1. Laparoscopically-induced parasitic myoma model: Xenograft of human uterine myoma in SCID mice. Part 2. Serum E2 levels of SCID mice. Part 3. Histological and immunohistochemistry (IHC) analysis. (DOC 52 kb)
Additional file 2: Table S2. of High-quality draft genome sequence and description of Haemophilus massiliensis sp. nov.
Creators: name: Cheikh Lo
name: Senthil Sankar
name: BĂŠcaye Fall
name: Bissoume Sambe-Ba
name: Silman Diawara
name: Gueye, Mamadou
name: Mediannikov, Oleg
name: Blanc-Tailleur, Caroline
name: Boubacar Wade
name: Raoult, Didier
name: Pierre-Edouard Fournier
name: Fenollar, Florence
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Differential characteristics of Haemophilus massiliensis strain FF7T (data from this study), H. influenzae strain ATCC 33391T [1, 33], H. sputorum strain CCUG 13788T [38, 39], H. pittmaniae strain HK 85T [40, 41], Haemophilus felis strain TI189T [42, 43] and H. parasuis strain ATCC 19417T [33, 41]. na = data not available. (DOC 57 kb)
MOESM1 of Cytokine gene polymorphisms are not associated with anti-PvDBP, anti-PvAMA-1 or anti-PvMSP-119 IgG antibody levels in a malaria-endemic area of the Brazilian Amazon
Creators: name: Furini, Adriana
name: Capobianco, Marcela
name: Storti-Melo, Luciane
name: Maristela Cunha
name: Cassiano, Gustavo
name: Machado, Ricardo
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. IgG antibody levels to PvAMA-1, PvDBP and PvMSP-119.
Additional file 3: Figure S1. of High-quality draft genome sequence and description of Haemophilus massiliensis sp. nov.
Creators: name: Cheikh Lo
name: Senthil Sankar
name: BĂŠcaye Fall
name: Bissoume Sambe-Ba
name: Silman Diawara
name: Gueye, Mamadou
name: Mediannikov, Oleg
name: Blanc-Tailleur, Caroline
name: Boubacar Wade
name: Raoult, Didier
name: Pierre-Edouard Fournier
name: Fenollar, Florence
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Reference mass spectrum from Haemophilus massiliensis strain FF7T. Spectra from 12 individual colonies were compared and a reference spectrum was generated. (DOCX 25 kb)
Structure-guided discovery of novel dUTPase inhibitors with anti-Nocardia activity by computational design
Creators: name: Wang, Zhi-Zheng
name: Weng, Jun
name: Qi, Jing
name: Fu, Xin-Xin
name: Xing, Ban-Bin
name: Hu, Yang
name: Huang, Chun-Hsiang
name: Chen, Chin-Yu
name: Wei, Zigong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology

description: The zoonosis caused by Nocardia is increasing seriously. But commonly used antibiotic drugs often lead to resistance. N. seriolae dUTPase (NsdUTPase) plays a key role in the proliferation of Nocardia, and was regarded as a potent drug target. However, there was little report about the NsdUTPase inhibitors. In this study, we discovered a series of novel NsdUTPase inhibitors to fight against Nocardia. The first crystal structure of NsdUTPase was released, and a structure-based computational design was performed. Compounds 4b and 12b exhibited promising activities towards NsdUTPase (IC50 = 0.99 μM and 0.7 μM). In addition, they showed satisfied anti-Nocardia activity (MIC value ranges from 0.5 to 2 mg/L) and low cytotoxicity, which were better than approved drugs oxytetracycline and florfenicol. Molecular modelling study indicated that hydrophobic interaction might be the main contribution for ligand binding. Our results suggested that NsdUTPase inhibitors might be a useful way to repress Nocardia.
Additional file 1: of EMBalance - validation of a decision support system in the early diagnostic evaluation and management plan formulation of balance disorders in primary care: study protocol of a feasibility randomised controlled trial
Creators: name: Rammazzo, Laura
name: Kikidis, Dimitris
name: Anwer, Amal
name: Macdonald, Nora
name: Kyrodimos, Efthymios
name: Maurer, Christoph
name: Wuyts, Floris
name: Luxon, Linda
name: Bibas, Athanasios
name: Doris-Eva Bamiou
Publisher: name: Figshare
Year: 2016
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: SPIRIT checklist. (DOC 121 kb)
Additional file 4: of A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease
Creators: name: Hatterer, Eric
name: Limin Shang
name: Simonet, Pierre
name: Herren, Suzanne
name: Daubeuf, Bruno
name: StĂŠphanie Teixeira
name: Reilly, James
name: Elson, Greg
name: Nelson, Robert
name: Gabay, Cem
name: Sokolove, Jeremy
name: McInnes, Iain
name: Kosco-Vilbois, Marie
name: Ferlin, Walter
name: Monnet, Emmanuel
name: Min, Cristina De
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: NI-0101 specifically blocked human TLR4 but not other members of the TLR family. NI-0101 blocked TLR4-induced activation while having no effect on other TLRs. (DOCX 804 kb)
Swiss Mattenklee landraces, a distinct and diverse genetic resource of red clover (Trifolium pratense L.)
Creators: name: Kölliker, Roland
name: Herrmann, Doris
name: Boller, Beat
name: Widmer, Franco
Publisher: name: Springer
Year: 2003
Subjects: Mattenklee
Trifolium pratense L.
Landraces
Genetic variability
AFLP

description: Genetic variability within and among 19 landraces and cultivars of red clover (Trifolium pratense L.) was investigated by means of amplified fragment length polymorphism (AFLP) analysis in order to assess the potential value of Swiss Mattenklee landraces as genetic resources for plant breeding and the preservation of biodiversity. Populations were classified into three groups according to their origin and agronomic features: Mattenklee landraces (8), Mattenklee cultivars (8) and field clover cultivars (3). Analysis of molecular variance based on 276 polymorphic AFLP markers revealed 80% of total variability to be due to variability within populations while 12% were attributed to variability among groups. Stepwise discriminant analysis identified a subset of 126 AFLP markers which best separated individual plants into the three respective groups. Genetic distances between populations were considerably larger among groups than among populations within the same group, providing further evidence for the genetic distinction between Mattenklee landraces, Mattenklee cultivars and field clover cultivars. AFLP markers identified two landrace clusters, containing three and four populations respectively, which, together with one additional landrace, may sufficiently represent the genetic variability of all eight landraces investigated. The results of this study strongly suggest that Swiss Mattenklee landraces form a genetically distinct group of red clover. The data obtained provide criteria on how to efficiently manage, preserve and exploit Mattenklee germplasm.
Isolation, structure modification, and anti-rheumatoid arthritis activity of isopimarane-type diterpenoids from Orthosiphon aristatus
Creators: name: Luo, Yong-Xin
name: Gong, Xu
name: Su, Zhi-Cheng
name: Mo, Jin-Feng
name: Li, Dong-Li
name: Wu, Ri-Hui
name: Jin, Jing-Wei
name: Lang, Ming
name: Wang, Jin-Ping
name: Xu, Xue-Tao
name: Gan, Li-She
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Orthosiphon aristatus is a well-known folkloric medicine and herb for Guangdong soup for the treatment of rheumatism in China. Eight isopimarane-type and migrated pimarane-type diterpenoids (1-8), including a new one with a rarely occurring α,β-unsaturated diketone C-ring, were isolated from O. aristatus. Their structures were determined by spectroscopic methods and quantum chemical calculations. Furthermore, the most abundant compound, orthosiphol K, was structurally modified by modern synthetic techniques to give seven new derivatives (9-15). The anti-rheumatoid arthritis activity of these diterpenoids were evaluated on a TNF-α induced MH7A human rheumatoid fibroblast-like synoviocyte model. Compound 10 showed the most potent activity among these compounds. Based on their inhibitory effects on the release levels of IL-1β, the preliminary structure-activity relationships were concluded. Furthermore, western blot analysis revealed that 10 could increase the expression of IκBα and decrease the expression of NF-κB p65, and the expression levels of COX-2 and NLRP3 proteins were consequently down-regulated.
Additional file 9: of A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease
Creators: name: Hatterer, Eric
name: Limin Shang
name: Simonet, Pierre
name: Herren, Suzanne
name: Daubeuf, Bruno
name: StĂŠphanie Teixeira
name: Reilly, James
name: Elson, Greg
name: Nelson, Robert
name: Gabay, Cem
name: Sokolove, Jeremy
name: McInnes, Iain
name: Kosco-Vilbois, Marie
name: Ferlin, Walter
name: Monnet, Emmanuel
name: Min, Cristina De
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Receiver operating characteristic (ROC) curve analyses of anti-citrullinated peptides levels in RASF in predicting NI-0101 response. Detailed sensitivity and specificity levels with 95Â % confidence interval of the 3 citrullinated peptides. (DOCX 20 kb)
Preliminary investigation of an idiopathic muscle disease in farmed burbot Lota lota
Creators: name: Pietsch, Constanze
name: Tschudi, F.
name: Baumann, S.
name: Schmidt-Posthaus, H.
Publisher: name: Inter-Research
Year: 2020
Subjects: Aquaculture · Rearing conditions · Skin alterations · Sandy flesh disease

description: The rearing of less established fish species in recirculating aquaculture systems (RASs) is increasing, but may require adaptations of the rearing facilities if health impairments occur. We observed several health issues in burbot Lota lota reared for up to 2 yr in a RAS and used microbiological, histological and molecular-biological methods to identify the causative agents. Minor skin trauma led to the development of ulcers. In addition, several fillets of burbot showed pronounced granulomatous inflammation and calcification with signs of muscle fiber degeneration which resembled a condition called ‘sandy flesh disease’ in North American walleye. Several infectious agents were able to be excluded as a cause for the disease. Carnobacterium maltaromaticum was isolated in high numbers in some of the affected muscle tissue. However, the role of this bacterium or other causative agents or husbandry conditions remains to be elucidated.
Lutjanus madras
Creators: name: Swain, Ritanjali
name: Kisku, Subash
name: Nayak, Lakshman
name: Mishra, Subhrendu Sekhar
name: Patro, Shesdev
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Perciformes
Lutjanidae
Lutjanus
Lutjanus madras

description: 2. Lutjanus madras (Valenciennes, 1831): Indian snapper (Figure 2)
Material examined: EBEC /ZSI/F-13367, 1 ex., 165 mm SL, Gopalpur fish landing center, coll. R. Swain, 27 th October 2021
Diagnosis: D X, 13; A III, 8; P 16; V 1, 5; LL 51; GL 9+12. Body depth 2.95 and HL 2.78 times in SL; eye diameter 3.73 times, suborbital depth 6.19 times in HL; suborbital depth less than eye diameter; preopercular notch and knob well developed; vomerine tooth patch crescentic without medial posterior extension; tongue smooth, without teeth; 7 transverse scale rows on cheek; caudal fin emarginated; scale rows above lateral line rising obliquely. Colour: Dorsal surface of body brownish and fins yellow except pelvic fins.
Distribution: Indo-West Pacific: Seychelles and Maldives to New Guinea and the Philippines (Froece & Pauly, 2021). India – Tamil Nadu (Krishnan et al., 2007), Kerala (Day, 1865), Andaman & Nicobar Islands (Talwar, 1990), Lakshadweep Islands (Allen, 1985) and Odisha (present report).
Remarks: This species also occurs in Lakshadweep Islands (Allen, 1985; Froece & Pauly, 2021), but not included in Rajan et al. (2021). As given the distribution map by Allen (1985) this species is available all along the east coast of India, but there was no material evidence of this species from Odisha, West Bengal or Andhra Pradesh (Barman, 2017). The present paper provides material evidence with regard to the occurrence of Lutjanus madras from the Odisha coast for the first time amounting to its first record from the state.
description: Published as part of Swain, Ritanjali, Kisku, Subash, Nayak, Lakshman, Mishra, Subhrendu Sekhar & Patro, Shesdev, 2022, First record of four snapper fishes (Perciformes: Lutjanidae) from Odisha, East coast of India, pp. 43-49 in Records of the Zoological Survey of India 122 (1) on page 44, DOI: 10.26515/rzsi/v122/i1/2022/167436, http://zenodo.org/record/10913879