cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Extracellular stimulation of VSIG4/complement receptor Ig suppresses intracellular bacterial infection by inducing autophagy
Creators: name: Kim, Kwang H.
name: Choi, Beom K.
name: Kim, Young H.
name: Chungyong Han
name: Oh, Ho S.
name: Lee, Don G.
name: Kwon, Byoung S.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Pharmacology
subject: Evolutionary Biology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: VSIG4/CRIg (V-set and immunoglobulin domain containing 4) is a transmembrane receptor of the immunoglobulin superfamily that is expressed specifically on macrophages and mature dendritic cells. VSIG4 signaling accelerates phagocytosis of C3-opsonized bacteria, thereby efficiently clearing pathogens within macrophages. We found that VSIG4 signaling triggered by C3-opsonized Listeria (opLM) or by agonistic anti-VSIG4 monoclonal antibody (mAb) induced macrophages to form autophagosomes. VSIG4-induced autophagosomes were selectively colocalized with the intracellular LM while starvation-induced autophagosomes were not. Consistent with these results, the frequency of autophagosomes induced by infection with opLM was lower in VSIG4-deficient bone marrow-derived macrophages (BMDMs) than in WT BMDMs. Furthermore, when VSIG4 molecules were overexpressed in HeLa cells, which are non-macrophage cells, VSIG4 triggering led to efficient uptake of LM, autophagosome formation, and killing of the infected LM. These findings suggest that VSIG4 signaling not only promotes rapid phagocytosis and killing of C3-opsonized intracellular bacteria, as previously reported, but also induces autophagosome formation, eliminating the LM that have escaped from phagosomes. We conclude that VSIG4 signaling provides an anti-immune evasion mechanism that prevents the outgrowth of intracellular bacteria in macrophages.
Translation of Tudor-SN, a novel terminal oligo-pyrimidine (TOP) mRNA, is regulated by the mTORC1 pathway in cardiomyocytes
Creators: name: Gan, Shihu
name: Su, Chao
name: Ma, Jinzheng
name: Liu, Mingxia
name: Cui, Xiaoteng
name: Xin, Lingbiao
name: Ren, Yuanyuan
name: Gao, Xingjie
name: Ge, Lin
name: Wei, Minxin
name: Yang, Jie
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: The mechanisms that regulate cell-cycle arrest of cardiomyocytes during heart development are largely unknown. We have previously identified Tudor staphylococcal nuclease (Tudor-SN) as a cell-cycle regulator and have shown that its expression level was closely related to cell-proliferation capacity. Herein, we found that Tudor-SN was highly expressed in neonatal mouse myocardia, but it was lowly expressed in that of adults. Using Data Base of Transcription Start Sites (DBTSS), we revealed that Tudor-SN was a terminal oligo-pyrimidine (TOP) mRNA. We further confirmed that the translational efficiency of Tudor-SN mRNA was controlled by the mammalian target of rapamycin complex 1 (mTORC1) pathway, as revealed via inhibition of activated mTORC1 in primary neonatal mouse cardiomyocytes and activation of silenced mTORC1 in adult mouse myocardia; additionally, this result was recapitulated in H9c2 cells. We also demonstrated that the downregulation of Tudor-SN in adult myocardia was due to inactivation of the mTORC1 pathway to ensure that heart growth was in proportion to that of the rest of the body. Moreover, we revealed that Tudor-SN participated in the mTORC1-mediated regulation of cardiomyocytic proliferation, which further elucidated the correlation between Tudor-SN and the mTORC1 pathway. Taken together, our findings suggest that the translational efficiency of Tudor-SN is regulated by the mTORC1 pathway in myocardia and that Tudor-SN is involved in mTORC1-mediated regulation of cardiomyocytic proliferation and cardiac development.
title: Multi-Modality Breast MRI Segmentation Using nn-UNet for Preoperative Planning of Robotic Surgery Navigation
Creators: name: Alqaoud, Motaz
name: Plemmons, John
name: Feliberti, Eric
name: Kaipa
name: Dong, Siqin
name: Fichtinger, Gabor
name: Xiao, Yimming
name: Audette, Michel
Publisher: name: Old Dominion University Libraries
Year: 2022

description: Segmentation of the chest region and breast tissues is essential for surgery planning and navigation. This paper proposes the foundation for preoperative segmentation based on two cascaded architectures of deep neural networks (DNN) based on the state-of-the-art nnU-Net. Additionally, this study introduces a polyvinyl alcohol cryogel (PVA-C) breast phantom based on the segmentation of the DNN automated approach, enabling the experiments of navigation system for robotic breast surgery. Multi-modality breast MRI datasets of T2W and STIR images were acquired from 10 patients. Segmentation evaluation utilized the Dice Similarity Coefficient (DSC), segmentation accuracy, sensitivity, and specificity. First, a single class labeling was used to segment the breast region. Then it was employed as an input for three-class labeling to segment fat, fibroglandular (FGT) tissues, and tumorous lesions. The first architecture has a 0.95 DCS, while the second has a 0.95, 0.83, and 0.41 for fat, FGT, and tumor classes, respectively.
title: Senior Subject Gait Analysis Using Self-supervised Method
Creators: name: Yhdego, Haben
name: Audette, Michel
Publisher: name: Old Dominion University Libraries
Year: 2022

description: There are many issues regarding the technology used for fall detection gait analysis in the geriatric center of senior patients. The fall detection system used should examine the privacy of the patients and the flexibility of the system. Several researchers have developed fall detection using wearable sensors due to their flexibility and nature of privacy. Most of those developed methods are supervised deep learning methods. However, data annotation is expensive because we use camera video recording and playback of each participant’s recorded video to label the data. Moreover, labelling using a camera recording limits the flexible and private nature of wearable sensor-based fall detection. This paper presents how to use unlabelled data to pre-train our models and use labelled data to fine-tune those pre-trained weights. We collected unlabelled and labelled data and applied self-supervised learning to detect falls. First, we performed pre-training on the unlabeled data using ResNet model. After that, fine-tune and train ResNet using the labelled dataset. The experiment in this study suggested that the best performance can be achieved by using pre-trained weights of unlabelled data from the accelerometer and gyroscope sensors. Furthermore, oversampling and modified loss functions are used to handle the dataset’s imbalance classes. With the ResNet pre-trained weights and re-training using the labelled data, the experiments achieved an F1-Score of 0.98.
Proteolytic fragments of fibronectin function as matrikines driving the chemotactic affinity of prostate cancer cells to human bone marrow mesenchymal stromal cells via the α5β1 integrin
Creators: name: Raghav Joshi
name: Goihberg, Edi
name: Wenying Ren
name: Pilichowska, Monika
name: Mathew, Paul
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: The haematopoietic niche is contributed to by bone marrow-resident mesenchymal stromal cells (BM-MSCs) and subverted by prostate cancer cells. To study mechanisms by which BM-MSCs and prostate cancer cells may interact, we assessed the migration, invasion, adhesion and proliferation of bone-derived prostate cancer cells (PC-3) in co-culture with pluripotent human BM-MSCs. We observed a strong adhesive, migratory and invasive phenotype of PC-3 cells with BM- MSC-co-culture and set out to isolate and characterize the bioactive principle. Initial studies indicated that chemotaxis was secondary to a protein residing in the >100kDa fraction. Size-exclusion chromatography (SEC) recovered peak activity in a high-molecular weight fraction containing thrombospondin-1 (TSP1). While TSP1 immunodepletion decreased activity, put-back with purified TSP1 did not reproduce bioactivity. Further purification of the TSP1-containing high-molecular weight fraction of the BM-MSC secretome with heparin-affinity chromatography recovered bioactivity with highly restricted bands on polyacrylamide gel electrophoresis, determined by mass spectroscopy to be proteolytic fragments of fibronectin (FN). Put-back experiments with full-length FN permitted adhesion but failed to induce migration. Monospecific antibodies to FN blocked adhesion. Proteolytic cleavage of FN generated FN fragments which now induced migration. Neutralizing monoclonal antibodies to FN receptors α5 and β1 integrins, and α5 knockdown specifically blocked migration and adhesion. Conclusion: Fibronectin fragments (FNFr) function as matrikines driving the chemotactic affinity of prostate cancer cells via the α5β1 integrin. Taken together with the high-frequency of α5β1 expression in disseminated prostate cancer cells in bone marrow aspirates from patients, the FNFr/FN-α5β1 interaction warrants further study as a therapeutic target.
Attentional bias toward alcohol-related stimuli in heavy drinkers: evidence from dynamic eye movement recording
Creators: name: Roy-Charland, Annie
name: Plamondon, Andréanne
name: Homeniuk, Andrew S.
name: Corie Ann Flesch
name: Klein, Raymond M.
name: Stewart, Sherry H.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background: It has been proposed that attentional biases toward alcohol stimuli are contributing factors maintaining problematic drinking behavior. Objective: The main goal of the present set of studies was to provide an examination of dynamic attentional mechanisms associated with alcohol consumption derived from eye movement monitoring. Method: Undergraduate students were recruited for two studies. In Experiment 1, 80 students were exposed to complex scenes (containing alcohol-related cues or not) viewed at a self-determined presentation rate. In Experiment 2, 80 students were exposed to the stimuli for a fixed presentation time and asked to memorize the photographs. In both studies, participants completed the Khavari Alcohol Test (KAT) to measure their drinking behaviors. Results: Experiment 1 revealed that alcohol consumption was unrelated to eye movement measures on alcohol-related objects within pictures. However, results of Experiment 2 indicated that saccades into and out of the alcohol-related zones were more frequent as alcohol consumption increased. The time spent and the speed of the first fixation in the alcohol-related zone did not explain the variance in alcohol consumption. Conclusion: Attentional biases associated with alcohol consumption might be better understood in terms of dynamic attention mechanisms. More precisely, heavy drinker’s attention seems to be constantly drawn back to alcohol-related objects once they are first fixated and when attention is enforced through other cognitive demands. From a clinical viewpoint, dynamic attentional biases might contribute to the development or maintenance of alcohol-related problems and this observation might help guide attention-based interventions.
How widespread use of generative AI for images and video can affect the environment and the science of ecology
Creators: name: Rillig, Matthias C.
name: Mansour, India
name: Hempel, Stefan
name: Bi, Mohan
name: König-Ries, Birgitta
name: Kasirzadeh, Atoosa
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: artificial intelligence
subject: environment
subject: fraud
subject: generative AI
subject: science credibility
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Generative artificial intelligence (AI) models will have broad impacts on society including the scientific enterprise; ecology and environmental science will be no exception. Here, we discuss the potential opportunities and risks of advanced generative AI for visual material (images and video) for the science of ecology and the environment itself. There are clearly opportunities for positive impacts, related to improved communication, for example; we also see possibilities for ecological research to benefit from generative AI (e.g., image gap filling, biodiversity surveys, and improved citizen science). However, there are also risks, threatening to undermine the credibility of our science, mostly related to actions of bad actors, for example in terms of spreading fake information or committing fraud. Risks need to be mitigated at the level of government regulatory measures, but we also highlight what can be done right now, including discussing issues with the next generation of ecologists and transforming towards radically open science workflows.
Characterizing socially supportive environments relating to physical activity participation for young people with physical disabilities
Creators: name: Knibbe, Tara Joy
name: Biddiss, Elaine
name: Gladstone, Brenda
name: McPherson, Amy C.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Purpose: To explore the experiences of young people with physical disabilities relating to social inclusion and physical activity, in order to describe the characteristics of social environments that support participation in physical activity. Method: An iterative, qualitative design employed in-depth, semi-structured interviews with young people with physical disabilities aged 12–18 (n = 11). Data were analyzed using interpretive thematic analysis. Results: Young people described several ways that their social environments help motivate and support them in their physical activity participation. These include providing: fair and equitable participation beyond physical accommodations; belonging through teamwork; and socially supported independence. Conclusions: Supportive social environments characterized by equitable participation, a sense of belonging, and opportunities for interdependence, play a critical role in promoting the health and well-being of young people with physical disabilities. These characteristics are important to consider in the design of both integrated and dedicated physical activity programs.
Additional file 1 of Growth hormone receptor gene influences mitochondrial function and chicken lipid metabolism by AMPK-PGC1α-PPAR signaling pathway
Creators: name: Yang, Minmin
name: Hu, Bowen
name: Sun, Donglei
name: Zhao, Changbin
name: Wei, Haohui
name: Li, Dajian
name: Liao, Zhiying
name: Zhao, Yongxia
name: Liang, Jinping
name: Shi, Meiqing
name: Luo, Qingbin
name: Nie, Qinghua
name: Zhang, Xiquan
name: Zhang, Dexiang
name: Li, Hongmei
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 1: Table S1. Sanger sequencing of pcDNA3.1-GHR by universal primers.
A Hybrid Nodal-Staggered Pseudo-Spectral Electromagnetic Particle-In-Cell Method with Finite-Order Centering
Creators: name: Zoni, Edoardo
Publisher: name: Zenodo
Year: 2022

description: Archive of input files, output files, post-processing Python scripts, and job submission batch scripts, used for the journal article "A Hybrid Nodal-Staggered Pseudo-Spectral Electromagnetic Particle-In-Cell Method with Finite-Order Centering" by E. Zoni et al. (2022). Here's a brief description of the available post-processing Python scripts: Dispersion.py is the Python script that can be used to produce the plots in Figure 1. Stencil.py is the Python script that can be used to produce the plot in Figure 2. Energy.py is the Python script that can be used to produce the bottom plot in Figure 3 (needs output data to be processed). Centering.py is the Python script that can be used to produce the plots in Figure 4. ConvergenceL2.py is the Python script that can be used to produce the plot in Figure 11 (needs output data to be processed). ConvergenceRMS.py is the Python script that can be used to produce the plot in Figure 14 (needs output data to be processed). ZetaNCI.py is the Python script that can be used to produce the plot in Figure C.15. Here's a brief description of the available input files: The input files starting with the prefix inputs_2d_pulse_ are the ones used to produce the data for the plots in Figure 3. The input files starting with the prefix inputs_2d_qed_ are the ones used to produce the data for the plots in Figures 5, 6, 7, 8. The input files starting with the prefix inputs_3d_lwfa_ are the ones used to produce the data for the plots in Figures 10, 11. The input files starting with the prefix inputs_3d_pwfa_ are the ones used to produce the data for the plots in Figures 13, 14. The versions of WarpX, AMReX and PICSAR used to produce the data are written in the available output files, which follow the same naming conventions used for the input files.
title: 02_0661
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Spatial and Temporal Coordination of Traction Froces in One-Dimensional Cell Migration
Creators: name: Sangyoon J. Han
name: Rodriguez, Marita L.
name: Al-Rekabi, Zeinab
name: Sniadecki, Nathan J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Computational Biology

description: Migration of a fibroblast along a collagen fiber can be regarded as cell locomotion in one-dimension (1D). In this process, a cell protrudes forward, forms a new adhesion, produces traction forces, and releases its rear adhesion in order to advance itself along a path. However, how a cell coordinates its adhesion formation, traction forces, and rear release in 1D migration is unclear. Here, we studied fibroblasts migrating along a line of microposts. We found that when the front of a cell protruded onto a new micropost, the traction force produced at its front increased steadily, but did so without a temporal correlation in the force at its rear. Instead, the force at the front coordinated with a decrease in force at the micropost behind the front. A similar correlation in traction forces also occurred at the rear of a cell, where a decrease in force due to adhesion detachment corresponded to an increase in force at the micropost ahead of the rear. Analysis with a bio-chemo-mechanical model for traction forces and adhesion dynamics indicated that the observed relationship between traction forces at the front and back of a cell is possible only when cellular elasticity is lower than the elasticity of the cellular environment.
title: Das Konzept einer reflexiven Wirtschaftsdidaktik – Ideen für einen verstehensorientierten Wirtschaftsunterricht
title: The concept of a reflexive didactics of economics - Ideas for an understanding-oriented economic education
titleType: AlternativeTitle
Creators: name: Keipke, Yvette
Publisher: name: Universitätsbibliothek Siegen
Year: 2019
Subjects: subject: 370 Erziehung, Schul- und Bildungswesen
subject: Einführung Schulfach Wirtschaft-Politik in NRW
subject: Wirtschaftsdidaktik
subject: Introduction to economics and politics in NRW
subject: Economic didactics
subject: Ökonomische Bildung
subject: Wirtschaftspädagogik
subject: Bildungswesen
subject: Wirtschaft
subject: Volkswirtschaft

description: The dissertation is concerned with the elaboration of a holistic approach to economic understanding, in particular with the concept of a reflexive didactics of economics. Building on this, basic ideas for an understanding-oriented economic education will be developed conceptually and exemplarily. The basic idea of a reflexive didactics of economics is the holistic approach to processes of understanding. For this purpose, concepts of education diagnostics and of reflective learning from educational research are combined with teaching economic reasoning, the history of ideas and the approach of an understanding-oriented economic education. The research perspective of this study is directed towards a theoretical reconstruction and mapping of the processes of economic understanding. It will be shown how a structural-genetic process of development in regard to economic understanding and reasoning can be described, and how it can be measured though education diagnostics. For the theoretical reconstruction and mapping of processes of economic understanding, the threshold concept is linked with the concept of transformative learning, the concept of reflection loops and the concept of critical thinking in order to achieve an explanation of the successive levels of understanding and reflection. In addition, a taxonomy of reflection tools will be developed which trigger reflection loops and initiate processes of understanding and reflection. Finally, the concept of a reflexive didactics of economics is exemplified along the lines of an understanding-oriented classroom approach.
title: 01_0944
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
PLoSONE_MRI_CAD_paper
Creators: name: Meriem El Azami
name: Hammers, Alexander
name: Jung, Julien
name: Costes, Nicolas
name: Bouet, Romain
name: Lartizien, Carole
Publisher: name: figshare
Year: 2016
Subjects: subject: Biomarkers
subject: Neuroscience
subject: 110320 Radiology and Organ Imaging
subject: FOS: Clinical medicine

description: Voxelwise one-class SVM predictive models used to estimate the support distribution of brain patterns extracted from MRI images of healthy control subjects.
SPM models and the results of the statistical analysis comparing 11 patients suffering from intractale epilepsy againt the same population of healthy control subjects.
Two pairs of epimers and three undescribed diterpenoids from Pseudocaryopteris paniculata
Creators: name: Zhang, Cheng-Gang
name: Chen, Ting
name: Yang, Jun-Jie
name: Mao, Xu-Dong
name: Chou, Gui-Xin
Publisher: name: Taylor & Francis
Year: 2021
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: A phytochemical investigation on the petroleum ether partition of the whole plant of Pseudocaryopteris paniculata, yield seven new compounds: one phytanes diterpenoid (2Z,6E,10E) 14-keto-2,6,10-trimethyl pentadeca-2,6,10-trien-1-carboxylic acid (1), five clerodane diterpenoids: paniculatins A-E (2, 3a/3b, 4a/4b), one abietane diterpenoid: ent-uncinatone (5), together with 12 known compounds. Their structures were elucidated on the basis of 1D and 2D Nuclear Magnetic Resonance （NMR_, Infrared Radiation (IR), and mass spectroscopic data. Compound 2, 5, and 11 showed weak selective cytotoxic activity of 11 human cancer cell lines.
Better Understanding of the Metamorphosis of Pregnancy (BUMP): protocol for a digital feasibility study in women from preconception to postpartum.
Creators: name: Goodday, SM
name: Karlin, E
name: Brooks, A
name: Chapman, C
name: Karlin, DR
name: Foschini, L
name: Kipping, E
name: Wildman, M
name: Francis, M
name: Greenman, H
name: Li, Li
name: Schadt, E
name: Ghassemi, M
name: Goldenberg, A
name: Cormack, F
name: Taptiklis, N
name: Centen, C
name: Smith, S
name: Friend, S
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Protocol
/692/1807/2782
/631/443/494
protocol

description: Funder: 4YouandMe Sema4
description: The Better Understanding the Metamorphosis of Pregnancy (BUMP) study is a longitudinal feasibility study aimed to gain a deeper understanding of the pre-pregnancy and pregnancy symptom experience using digital tools. The present paper describes the protocol for the BUMP study. Over 1000 participants are being recruited through a patient provider-platform and through other channels in the United States (US). Participants in a preconception cohort (BUMP-C) are followed for 6 months, or until conception, while participants in a pregnancy cohort (BUMP) are followed into their fourth trimester. Participants are provided with a smart ring, a smartwatch (BUMP only), and a smart scale (BUMP only) alongside cohort-specific study apps. Participant centric engagement strategies are used that aim to co-design the digital approach with participants while providing knowledge and support. The BUMP study is intended to lay the foundational work for a larger study to determine whether participant co-designed digital tools can be used to detect, track and return multimodal symptoms during the perinatal window to inform individual level symptom trajectories.
Preliminary evaluation of a measure for reliable assessment of need for constant visual observation in adults with traumatic brain injury
Creators: name: Moessner, Anne
name: Malec, James F.
name: Beveridge, Scott
name: Reddy, Cara Camiolo
name: Huffman, Tracy
name: Marton, Julia
name: Schmerzler, Audrey J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Primary objective: To develop and provide initial validation of a measure for accurately determining the need for Constant Visual Observation (CVO) in patients with traumatic brain injury (TBI) admitted to inpatient rehabilitation. Research design: Rating scale development and evaluation through Rasch analysis and assessment of concurrent validity. Methods and procedures: One hundred and thirty-four individuals with moderate–severe TBI were studied in seven inpatient brain rehabilitation units associated with the National Institute for Disability, Independent Living and Rehabilitation Research (NIDILRR) TBI Model System. Participants were rated on the preliminary version of the CVO Needs Assessment scale (CVONA) and, by independent raters, on the Levels of Risk (LoR) and Supervision Rating Scale (SRS) at four time points during inpatient rehabilitation: admission, Days 2–3, Days 5–6 and Days 8–9. Outcomes and results: After pruning misfitting items, the CVONA showed satisfactory internal consistency (Person Reliability = 0.85–0.88) across time points. With reference to the LoR and SRS, low false negative rates (sensitivity > 90%) were associated with moderate-to-high false positive rates (29–56%). Conclusions: The CVONA may be a useful objective metric to complement clinical judgement regarding the need for CVO; however, further prospective study is desirable to further assess its utility in identifying at-risk patients, reducing adverse events and decreasing CVO costs.
Adoption of processing technologies and innovative food preservation techniques: findings from smallholders in the Lindi Region in Tanzania
Creators: name: Sarr, Malika
name: Majili, Zahra
name: Khalili, Niloofar
name: Matavel, Custodio Efraim
name: Mbwana, Hadijah Ally
name: Kaingo, Jacob
name: Löhr, Katharina
name: Rybak, Constance
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: adoption
subject: smallholder farmers
subject: Tanzania
subject: processing technology
subject: pigeon peas
subject: 630 Landwirtschaft und verwandte Bereiche

description: Adopting processing technologies and innovative food preservation is crucial for improving the food security and nutritional status of rural populations in Tanzania and other countries in the Global South. However, low adoption rates among smallholders highlight the need for a better understanding of farmers’ decision-making processes. The aim of this study is to examine extrinsic and intrinsic factors influencing smallholders’ decision-making processes in the adoption of innovative food processing and preservation techniques (specifically, pigeon pea flour-based products, threshers, dehullers) in Mitumbati and Mibure in the Lindi Region in Tanzania. Primary data on 555 farm households were collected using a standardized survey. Extrinsic influential factors were analyzed using binary logistic regression analysis. The results on internal decision-making are based on an analysis of barriers and motivations identified by farmers in relation to the uptake of the different innovations. Training and awareness emerged as the most significant factors positively associated with the adoption of all innovative processing and preservation techniques. Moreover, the results show that the primary drivers for smallholders in the study region to adopt innovative technologies were the potential health benefits and time savings they offered. The main challenge they faced was a lack of knowledge about the innovations. The results indicate that disseminating knowledge is crucial for the successful adoption of innovative processing technology in the study region. Improving and expanding training programs to be more inclusive can help to create incentives and overcome barriers, leading to increased adoption.
A comprehensive review of hookworm control strategies and future directions: A neglected worm-eye perspective
Creators: name: Kevin E.S.
name: John A.
name: Anieta M. J.
name: Clement P.
Publisher: name: gjrpublication
Year: 2025

description: This review delves into hookworm infections, which remain a significant global public health concern, particularly in low- and middle-income countries where inadequate sanitation and poverty facilitate their transmission. Current resource-limited settings where control strategies focus primarily on mass drug administration (MDA) with benzimidazole anthelmintics, such as albendazole and mebendazole. While MDA has led to a reduction in infection prevalence, its long-term efficacy is challenged by rapid reinfection, limited impact on morbidity, and the potential emergence of drug resistance. Integrated approaches combining MDA with improved water, sanitation, and hygiene (WASH) interventions along with health education and environmental modifications have shown promise but require sustained investment and community engagement. Advances in vaccine development, particularly recombinant and live-attenuated candidates, offer a potential long-term solution, though none are yet widely available. Novel strategies, such as targeted treatment based on diagnostic innovations in the future can make a difference. Additionally, One Health approaches that consider the zoonotic transmission dynamics of some hookworm species could enhance intervention effectiveness. Future research should prioritize sustainable, community-centred programs that integrate diagnostics, treatment, and prevention to achieve long-term elimination. Future control directions must focus on sustainable solutions such as hookworm vaccines, which show promise in preclinical and early clinical trials, and alternative therapies, including microbiome-based interventions and novel anthelmintic compounds. As global health priorities evolve, the need for renewed commitment to hookworm control must be emphasized to prevent the neglect of this parasitic disease. This review critically evaluates existing strategies and explores innovative solutions that could shape the future of hookworm control.
Use of horizontal subsurface flow constructed wetlands to treat reverse osmosis concentrate of rolling wastewater
Creators: name: Jingcheng Xu
name: Zhao, Gang
name: Xiangfeng Huang
name: Haobo Guo
name: Liu, Wei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: According to the characteristics of the reverse osmosis concentrate (ROC) generated from iron and steel company, we used three sets of parallel horizontal subsurface flow (HSF) constructed wetlands (CWs) with different plants and substrate layouts to treat the high-salinity wastewater. The plant growth and removal efficiencies under saline condition were evaluated. The evaluation was based entirely on routinely collected water quality data and the physical and chemical characteristics of the plants (Phragmites australis, Typha latifolia, Iris wilsonii, and Scirpus planiculmis). The principal parameters of concern in the effluent were chemical oxygen demand (COD), total nitrogen (TN), and total phosphorus (TP). The results showed that the CWs were able to remove COD, TN, and TP from ROC. S. planiculmis was not suitable for the treatment of high-saline wastewater. The sequence of metals accumulated in CW plants was K>Ca>Na>Mg>Zn>Cu. More than 70% of metals were accumulated in the aboveground of P. australis. The CW filled with gravel and manganese ore and planted with P. australis and T. latifolia had the best performance of pollutant removal, with average removal of 49.96%, 39.45%, and 72.01% for COD, TN, and TP, respectively. The effluent water quality met the regulation in China. These results suggested that HSF CW planted with P. australis and T. latifolia can be applied for ROC pollutants removal.
Supplementary document for Toroidal dipole resonances enable giant vortical dichroism in folded metamaterials - 7436701.pdf
Creators: name: Peng, Kangzhun
name: luo, shiqi
name: Li, Zhiyuan
name: Liang, Wenyao
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement document
THE COMPARETIVE ANALYSIS OF ADJECTIVES IN ENGLISH AND UZBEK LANGUAGES
Creators: name: Sharipova, Bahora
name: Inotova, Marjona
Publisher: name: Zenodo
Year: 2024

description: This article is devoted to the usage and draws an analogy to adjectives by the levels of morphology in two different languages.  Adjectives are seen in particularly different ways by Eastern and Western linguists, and even within setting to set side by sidein order to show differences and likenesses.  The past is over, but present you can seize, and make it for you in the immediate future. So, there are some similar and different features of adjectives which we have tried to demonstrate in English and Uzbek languages.
title: Risk-and-Resiliency-Intelligent Supply Chain (RRiSC)
Creators: name: Abdelnabi, Ahmad A.
name: Abdelmagid, Ahmed M.
name: Rabadi, Ghaith
name: Sousa-Poza, Andres
name: Pinto, C. Ariel
Publisher: name: Old Dominion University Libraries
Year: 2022

description: This work proposes a risk-and-resiliency-intelligent supply chain (RRiSC) tool which is an SC risk management framework that leverages cutting-edge technologies in Artificial Intelligence (AI), Big Data Analytics (BDA), and Digital Twins (DT) to develop specific capabilities for SC risk management. RRiSC is a convergence of mature tools and techniques embedded in three modules: Modeling, Simulation, and Visualization – all together integrate the optimization, simulation, and data analytics to test the performance of the whole supply network under different scenarios through measuring the vital KPIs, identifying the vulnerabilities, and setting proactive plans to diminish risks consequences.
Use of Horizontal Subsurface Flow Constructed Wetlands to treat Reverse Osmosis Concentrate of Rolling Wastewater
Creators: name: Jingcheng Xu
name: Zhao, Gang
name: Xiangfeng Huang
name: Haobo Guo
name: Liu, Wei
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: According to the characteristics of the reverse osmosis concentrate (ROC) generated from Iron and Steel Company, we used three sets of parallel horizontal subsurface flow (HSF) constructed wetlands with different plants and substrate layouts to treat the high salinty wastewater. The plant growth and removal efficiencies under saline condition were evaluated. The evaluation was based entirely on routinely-collected water quality data, physical and chemical characteristics of the plants (Phragmites australis, Typha latifolia, Iris wilsonii, and Scirpus planiculmis). The principal parameters of concern in the effluent were chemical oxygen demand (COD), total nitrogen (TN) and total phosphorus (TP). The results showed that the constructed wetlands were able to remove COD, TN and TP from ROC. S. planiculmis was not suitable for treatment of high saline wastewater. The amount of metals accumulated in constructed wetland plants was sequencing as K>Ca>Na>Mg>Zn>Cu. More than 70% of metals were accumulated in the aboveground of Phragmites australis. The constructed wetland filled with gravel and manganese ore and planted with Phragmites australis, Typha latifolia had the best performance of pollutant removal, with average removal of 49.96%, 39.45% and 72.01% for COD, TN and TP, respectively. The effluent water quality met the regulation in China. These results suggested HSF constructed wetland planted with Phragmites australis and Typha latifolia can be applied in ROC pollutants removal.
Additional file 2 of Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital
Creators: name: Duan, Zhongliang
name: Qin, Juanxiu
name: Liu, Yao
name: Li, Cui
name: Ying, Chunmei
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2: Table S1. Primers for MLST, biofilm, and virulence genes of S. maltophilia.
title: 02_0210
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Synthesis and characterization of Co (II) and Fe (III) Schiff base complexes grafted onto mesoporous MCM-41: A heterogeneous and recyclable nanocatalysts for the selective oxidation of sulfides and oxidative coupling of thiols
Creators: name: Nourolah Noori
name: Nikoorazm, Mohsen
name: Ghorbani-Choghamarani, Arash
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology

description: Novel organic–inorganic hybrid heterogeneous catalysts containing cobalt(II) and iron(III) Schiff base complexes, grafted on the internal surface of MCM-41 pores were prepared by introducing a metal salt into a mesoporous silica functionalized with a Schiff base ligand. The chemical and physical properties of the catalysts were investigated by BET, TGA, XRD, FT-IR, and TEM techniques. These complexes were found to be efficient, selective catalysts for the oxidation of various sulfides to sulfoxides and oxidative coupling of thiols to their corresponding disulfides with urea hydrogen peroxide in excellent yield at room temperature. The designed catalytic system prevents effectively the overoxidation of sulfides and thiols to sulfoxides and sulfones, respectively. Also the heterogeneous catalysts can be recovered easily and reused many times without significant loss of activity and selectivity.