cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A criterion for existence of right-induced model structures
Creators: name: Drummond-Cole, Gabriel C.
name: Hackney, Philip
Publisher: name: arXiv
Year: 2017
Subjects: subject: Category Theory (math.CT)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics

description: Suppose that $F: \mathcal{N} \to \mathcal{M}$ is a functor whose target is a Quillen model category. We give a succinct sufficient condition for the existence of the right-induced model category structure on $\mathcal{N}$ in the case when $F$ admits both adjoints. We give several examples, including change-of-rings, operad-like structures, and anti-involutive structures on infinity categories. For the last of these, we explore anti-involutive structures for several different models of $(\infty, 1)$-categories, and show that known Quillen equivalences between base model categories lift to equivalences.
Current cosmological constraints from a 10 parameter CMB analysis
Creators: name: Tegmark, Max
name: Zaldarriaga, Matias
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We compute the constraints on a ``standard'' 10 parameter cold dark matter (CDM) model from the most recent CMB and data and other observations, exploring 30 million discrete models and two continuous parameters. Our parameters are the densities of CDM, baryons, neutrinos, vacuum energy and curvature, the reionization optical depth, and the normalization and tilt for both scalar and tensor fluctuations. Our strongest constraints are on spatial curvature, -0.24 < Omega_k < 0.38, and CDM density, h^2 Omega_cdm <0.3, both at 95%. Including SN 1a constraints gives a positive cosmological constant at high significance. We explore the robustness of our results to various assumptions. We find that three different data subsets give qualitatively consistent constraints. Some of the technical issues that have the largest impact are the inclusion of calibration errors, closed models, gravity waves, reionization, nucleosynthesis constraints and 10-dimensional likelihood interpolation.
description: Replaced to match published ApJ version. More details added. 13 ApJ pages. CMB movies and color figs at http://www.hep.upenn.edu/~max/10par_frames.html or from max@physics.upenn.edu
Large-Range Tuning and Stabilization of the Optical Transition of Diamond Tin-Vacancy Centers by In-Situ Strain Control
Creators: name: Brevoord, Julia M.
name: Wienhoven, Leonardo G. C.
name: Codreanu, Nina
name: Ishiguro, Tetsuro
name: van Leeuwen, Elvis
name: Iuliano, Mariagrazia
name: De Santis, Lorenzo
name: Waas, Christopher
name: Beukers, Hans K. C.
name: Turan, Tim
name: Errando-Herranz, Carlos
name: Kawaguchi, Kenichi
name: Hanson, Ronald
Publisher: name: arXiv
Year: 2025
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The negatively charged tin-vacancy (SnV-) center in diamond has emerged as a promising platform for quantum computing and quantum networks. To connect SnV- qubits in large networks, in-situ tuning and stabilization of their optical transitions are essential to overcome static and dynamic frequency offsets induced by the local environment. Here we report on the large-range optical frequency tuning of diamond SnV- centers using micro-electro-mechanically mediated strain control in photonic integrated waveguide devices. We realize a tuning range of >40 GHz, covering a major part of the inhomogeneous distribution. In addition, we employ real-time feedback on the strain environment to stabilize the resonant frequency and mitigate spectral wandering. These results provide a path for on-chip scaling of diamond SnV-based quantum networks.
Additional file 1 of Construction of Pd Single Site Anchored on Nitrogen-Doped Porous Carbon and Its Application for Total Antioxidant Level Detection
Creators: name: Zhang, Jingwen
name: Li, Zhi
name: Li, Hui
name: Dai, Ge
name: Luo, Feifei
name: Chu, Zhaohui
name: Geng, Xing
name: Zhang, Fan
name: Wang, Qingjiang
Publisher: name: figshare
Year: 2022
Subjects: Biophysics
Biochemistry
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Additional file 1. Fig.S1. XRD pattern of the SA-Pd/NPC. Fig.S2 TEM-EDS spectrum of SA-Pd/NPC. Fig.S3 FT-IR spectrum of SA-Pd/NPC. Fig.S4 Pore size distribution. Fig.S5 Optimization of experimental conditions. Table S1 EDX element content of the SA-Pd/NPC. Table S2 Comparison of the apparent kinetic parameters of different peroxidase mimics. Table S3 The respective concentrations of physiologically relevant antioxidant components. Table S4 Detection of AA and GSH in the human saliva samples
Unveiling the sensory and interneuronal pathways of the neuroendocrine connectome in Drosophila.
Creators: name: Hückesfeld, Sebastian
name: Schlegel, Philipp
name: Miroschnikow, Anton
name: Schoofs, Andreas
name: Zinke, Ingo
name: Haubrich, André N
name: Schneider-Mizell, Casey M
name: Truman, James W
name: Fetter, Richard D
name: Cardona, Albert
name: Pankratz, Michael J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Carbon dioxide
Neuropeptides
Neuroscience
Interneuron
Neuroendocrine System
Connectome
D. Melanogaster
Sensory Synapses

description: Neuroendocrine systems in animals maintain organismal homeostasis and regulate stress response. Although a great deal of work has been done on the neuropeptides and hormones that are released and act on target organs in the periphery, the synaptic inputs onto these neuroendocrine outputs in the brain are less well understood. Here, we use the transmission electron microscopy reconstruction of a whole central nervous system in the Drosophila larva to elucidate the sensory pathways and the interneurons that provide synaptic input to the neurosecretory cells projecting to the endocrine organs. Predicted by network modeling, we also identify a new carbon dioxide-responsive network that acts on a specific set of neurosecretory cells and that includes those expressing corazonin (Crz) and diuretic hormone 44 (Dh44) neuropeptides. Our analysis reveals a neuronal network architecture for combinatorial action based on sensory and interneuronal pathways that converge onto distinct combinations of neuroendocrine outputs.
Adaptive Sampling for Multi-Robot Wide-Area Exploration
Creators: name: Low, Kian Hsiang
name: Gordon, Geoffrey
name: Dolan, John M.
name: Khosla, Pradeep
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: subject: 80101 Adaptive Agents and Intelligent Robotics
subject: FOS: Computer and information sciences

description: The exploration problem is a central issue in mobile robotics. A complete coverage is not practical if the environment is large with a few small hotspots, and the sampling cost is high. So, it is desirable to build robot teams that can coordinate to maximize sampling at these hotspots while minimizing resource costs, and consequently learn more accurately about properties of such environmental phenomena. An important issue in designing such teams is the exploration strategy. The contribution of this paper is in the evaluation of an adaptive exploration strategy called Adaptive Cluster Sampling (ACS), which is demonstrated to reduce the resource costs (i.e., mission time and energy consumption) of a robot team, and yield more information about the environment by directing robot exploration towards hotspots. Due to the adaptive nature of the strategy, it is not obvious how the sampled data can be used to provide unbiased, low-variance estimates of the properties. This paper therefore discusses how estimators that are Rao-Blackwellized can be used to achieve low error. This paper also presents the first analysis of the characteristics of the environmental phenomena that favor the ACS strategy and estimators. Quantitative experimental results in a mineral prospecting task simulation show that our approach is more efficient in exploration by yielding more minerals and information with fewer resources and providing more precise mineral density estimates than previous methods.
Neutral Heavy Leptons and Electroweak Baryogenesis
Creators: name: Hernandez, P.
name: Rius, N.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the possibility that baryogenesis occurs during the weak phase transition in a minimal extension of the Standard Model which contains extra neutral leptons and conserves total lepton number. The necessary CP-violating phases appear in the leptonic Yukawa couplings. We compute the CP-asymmetries in both the neutral and the charged lepton fluxes reflected on the bubble wall. Using present experimental bounds on the mixing angles and Standard Model estimates for the parameters related to the scalar potential, we conclude that it seems unlikely to produce the observed baryon to entropy ratio within this type of models. We comment on the possibility that the constraints on the mixings might be naturally relaxed due to small finite temperature effects.
description: 21 pages (4 Figures)
A universal macroscopic theory of surface plasma waves and their losses
Creators: name: Deng, Hai-Yao
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Recently, we have revealed an intrinsic instability of metals due to surface plasma waves (SPWs) and raised the prospect of using it to create lossless SPWs. The counter-intuitive nature of this finding prompts one to ask, why had not this instability been disclosed before, given the long history of this subject? If this instability does exist, how far is it from reality? The present work is devoted to answering these questions. To this end, we derive a unified macroscopic theory of SPWs that applies to any type of electron dynamics, be they local or non-local, classical or quantum-mechanical. In light of this theory, we analyze the behaviors of SPWs according to several electron dynamics models, including the widely used local dielectric model (DM), the hydrodynamic model (HDM) and the specular reflection model (SRM), in addition to the less common semi-classical model (SCM). We find that, in order to unveil the instability, one must (i) self-consistently treat surface effects without any of the usually imposed auxiliary conditions and (ii) include translation symmetry breaking effects in electron dynamics. As far as we are concerned, none existing work had fulfilled both (i) and (ii). To assess the possibility of realizing the instability, we analyze two very important factors: the dielectric interfacing the metal and inter-band transitions, which both were ignored in our recent work. Whereas inter-band absorption -- together with Landau damping -- is shown adverse to the instability, a dielectric brings it closer to occurrence. One may even attain it in common plasmonic materials such as silver under not so tough conditions.
description: 16 pages, 6 figures, title changed, rewrite of the Introduction and abstract, restructuring, Fig. 2 deleted, Appendix B added, more references added, material in Sec. VI has some overlap with arXiv:1706.03404 (not to be submitted)
Adaptive Multi-Robot Wide-Area Exploration and Mapping
Creators: name: Low, Kian Hsiang
name: Dolan, John
name: Khosla, Pradeep
Publisher: name: Carnegie Mellon University
Year: 2008
Subjects: subject: 80101 Adaptive Agents and Intelligent Robotics
subject: FOS: Computer and information sciences

description: The exploration problem is a central issue in mobile robotics. A complete terrain coverage is not practical if the environment is large with only a few small hotspots. This paper presents an adaptive multi-robot exploration strategy that is novel in performing both wide-area coverage and hotspot sampling using non-myopic path planning. As a result, the environmental phenomena can be accurately mapped. It is based on a dynamic programming formulation, which we call the Multi-robot Adaptive Sampling Problem (MASP). A key feature of MASP is in covering the entire adaptivity spectrum, thus allowing strategies of varying adaptivity to be formed and theoretically analyzed in their performance; a more adaptive strategy improves mapping accuracy. We apply MASP to sampling the Gaussian and log- Gaussian processes, and analyze if the resulting strategies are adaptive and maximize wide-area coverage and hotspot sampling. Solving MASP is non-trivial as it comprises continuous state components. So, it is reformulated for convex analysis, which allows discrete-state monotone-bounding approximation to be developed. We provide a theoretical guarantee on the policy quality of the approximate MASP (aMASP) for using inMASP. Although aMASP can be solved exactly, its state size grows exponentially with the number of stages. To alleviate this computational difficulty, anytime algorithms are proposed based on aMASP, one of which can guarantee its policy quality for MASP in real time.
Nanooptomechanical Transduction in a Single Crystal with 100% Photoconversion.
Creators: name: Cole, Jacqueline M
name: Gosztola, David J
name: Velazquez-Garcia, Jose De J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021

description: Materials that exhibit nanooptomechanical transduction in their single-crystal form have prospective use in light-driven molecular machinery, nanotechnology, and quantum computing. Linkage photoisomerization is typically the source of such transduction in coordination complexes, although the isomers tend to undergo only partial photoconversion. We present a nanooptomechanical transducer, trans-[Ru(SO2)(NH3)4(3-bromopyridine)]tosylate2, whose S-bound η1-SO2 isomer fully converts into an O-bound η1-OSO photoisomer that is metastable while kept at 100 K. Its 100% photoconversion is confirmed structurally via photocrystallography, while single-crystal optical absorption and Raman spectroscopies reveal its metal-to-ligand charge-transfer and temperature-dependent characteristics. This perfect optical switching affords the material good prospects for nanooptomechanical transduction with single-photon control.
Fragmentation Instability of Molecular Clouds: Numerical Simulations
Creators: name: Indebetouw, R.
name: Zweibel, E. G.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We simulate fragmentation and gravitational collapse of cold, magnetized molecular clouds. We explore the nonlinear development of an instability mediated by ambipolar diffusion, in which the collapse rate is intermediate to fast gravitational collapse and slow quasistatic collapse. Initially uniform stable clouds fragment into elongated clumps with masses largely determined by the cloud temperature, but substantially larger than the thermal Jeans mass. The clumps are asymmetric, with significant rotation and vorticity, and lose magnetic flux as they collapse. The clump shapes, intermediate collapse rates, and infall profiles may help explain observations not easily fit by contemporary slow or rapid collapse models.
description: 25pp, 20 small eps figures, in press ApJ, April 1, 2000
Sulfatase-cleavable linkers for antibody-drug conjugates.
Creators: name: Bargh, Jonathan D
name: Walsh, Stephen J
name: Isidro-Llobet, Albert
name: Omarjee, Soleilmane
name: Carroll, Jason S
name: Spring, David R
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Antibody-drug conjugates (ADCs) are a class of targeted drug delivery agents combining the cell-selectivity of monoclonal antibodies (mAbs) and the cytotoxicity of small molecules. These two components are joined by a covalent linker, whose nature is critical to the efficacy and safety of the ADC. Enzyme-cleavable dipeptidic linkers have emerged as a particularly effective ADC linker type due to their ability to selectively release the payload in the lysosomes of target cells. However, these linkers have a number of drawbacks, including instability in rodent plasma and their inherently high hydrophobicity. Here we show that arylsulfate-containing ADC linkers are cleaved by lysosomal sulfatase enzymes to tracelessly release their payload, while circumventing the instability problems associated with dipeptide-linkers. When incorporated with trastuzumab and the highly potent monomethyl auristatin E (MMAE) payload, the arylsulfate-containing ADC 2 and ADC 3 were more cytotoxic than the non-cleavable ADC 4 against HER2-positive cells, while maintaining selectivity over HER2-negative cells. We propose that the stability, solubility and synthetic tractability of our arylsulfate linkers make them an attractive new motif for cleavable ADC linkers, with clear benefits over the widely used dipeptidic linkers.
title: Table des matières_La Lumière électrique chez soi par la pile Daniell modifiée
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Table des matières
Adaptive Kalman Filtering Methods for Low-Cost GPS/INS Localization for Autonomous Vehicles
Creators: name: Werries, Adam
name: Dolan, John M.
Publisher: name: Carnegie Mellon University
Year: 2016
Subjects: subject: 80101 Adaptive Agents and Intelligent Robotics
subject: FOS: Computer and information sciences

description: For autonomous vehicles, navigation systems must be accurate enough to provide lane-level localization. Highaccuracy sensors are available but not cost-effective for production use. Although prone to significant error in poor circumstances, even low-cost GPS systems are able to correct Inertial Navigation Systems (INS) to limit the effects of dead reckoning error over short periods between sufficiently accurate GPS updates. Kalman filters (KF) are a standard approach for GPS/INS integration, but require careful tuning in order to achieve quality results. This creates a motivation for a KF which is able to adapt to different sensors and circumstances on its own. Typically for adaptive filters, either the process (Q) or measurement (R) noise covariance matrix is adapted, and the other is fixed to values estimated a priori. We show that by adapting Q based on the state-correction sequence and R based on GPS receiver-reported standard deviation, our filter reduces GPS root-mean-squared error by 23% in comparison to raw GPS, with 15% from only adapting R.
Additional file 2 of Enhanced accumulation of oil through co-expression of fatty acid and ABC transporters in Chlamydomonas under standard growth conditions
Creators: name: Chen, Ru
name: Yang, Miao
name: Li, Mengjie
name: Zhang, Hao
name: Lu, Han
name: Dou, Xiaotan
name: Feng, Shiqi
name: Xue, Song
name: Zhu, Chenba
name: Chi, Zhanyou
name: Kong, Fantao
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 2: Table S1. All primer sequences used in this study.
Red Giants in the Halo of the S0 Galaxy NGC 3115: A Distance and a Bimodal Metallicity Distribution
Creators: name: Elson, Rebecca A. W.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Using the Hubble Space Telescope, we resolve the red giant branch in the halo of the S0 galaxy NGC 3115. We measure magnitudes and $(V-I)$ colours for stars down to 1.5 magnitudes below the tip of the red giant branch. From the brightest stars we estimate a distance modulus $(m-M)_0=30.21 \pm 0.30$, corresponding to a distance of $11.0 \pm 1.5$ Mpc. This is in excellent agreement with the value $(m-M)_0=30.17 \pm 0.13$ determined from the planetary nebula luminosity function. Our results rule out the shorter distance modulus $(m-M)_0=29.65$ determined from surface brightness fluctuations. A histogram of $(V-I)$ colours shows a clear bimodality, indicating the presence of two distinct halo populations of roughly equal size. One has [Fe/H]$\sim -0.7$ and one has [Fe/H]$\sim -1.3$. This is the most distant galaxy in which a Population II halo has been resolved, and it is the first time a colour bimodality has been observed among the halo stars of any early-type galaxy.
description: 15 pages, 4 figures. MNRAS, in press
Cosmic no-hair theorems for viscous contracting Universes
Creators: name: Ganguly, Chandrima
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: paper
alternatives to inflation
cosmic singularity
physics of the early universe

description: Abstract: A cosmic no-hair theorem for all initially contracting, spatially homogeneous, orthogonal Bianchi Cosmologies is derived - which shows that all such Universes asymptote to a spatially flat, isotropic Universe with the inclusion of a shear viscous stress. This establishes a new mechanism of isotropisation in a contracting Universe, which does not take recourse to an ekpyrosis-like mechanism using an effective ultra-stiff equation of state fluid, that is, one in which the pressure is much greater than the energy density.
Magnetic instability of quark matter
Creators: name: Tatsumi, Toshitaka
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Spontaneous magnetization of quark liquid is examined. It is pointed out that quark liquid has potential to be ferromagnetic at rather low densities.
description: 7 page, 3 figures
Numerical simulation of accretion discs in close binary systems and discovery of spiral shocks
Creators: name: Matsuda, Takuya
name: Makita, Makoto
name: Fujiwara, Hidekazu
name: Nagae, Takizo
name: Haraguchi, Kei
name: Hayashi, Eiji
name: Boffin, H. M. J.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The history of hydrodynamic numerical simulations for accretion disks in close binary systems is reviewed, in which emphasis is placed, in particular, on the facts that spiral shock waves were numerically found in 1986 by researchers including one of the present authors and that spiral structure was discovered in IP Pegasi in 1997 by Steeghs et al. The results of our two and three-dimensional numerical simulations in recent years are then summarized, with comparison being made with observations.
description: 16 pages, LaTeX with 14 eps figures using kluwer.cls. Submitted to Astrophysics and Space Science
On three dimensional multivariate version of q-Normal distribution and probabilistic interpretations of Askey--Wilson, Al-Salam--Chihara and q-ultraspherical polynomials
Creators: name: Szabłowski, Paweł J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 62H86, 60E99, 05A30, 33D45

description: We study properties of compactly supported, 4 parameter \newline $(ρ_{12},ρ_{23},ρ_{13},q)\in (-1,1)^{\times 4}$ family of continuous type 3 dimensional distributions, that have the property that for $q\rightarrow 1^{-}$ this family tends to some 3 dimensional Normal distribution. For $q=0$ we deal with 3 dimensional generalization of Kesten--McKay distribution. In a very special case when $ρ_{12}ρ_{13}ρ_{23}=q$ all one dimensional marginals are identical, semicircle distributions. We find both all marginal as well as all conditional distributions. Moreover, we find also families of polynomials that are orthogonalized by these one-dimensional margins and one-dimensional conditional distributions. Consequently, we find moments of both conditional and unconditional distributions of dimensions one and two. In particular, we show that all one-dimensional and two-dimensional conditional moments of, say, order $n$ and are polynomials of the same order $n$ in the conditioning random variables. Finding above mentioned orthogonal polynomials leads us to a probabilistic interpretation of these polynomials. Among them are the famous Askey-Wilson, Al-Salam--Chihara polynomials considered in the complex, but conjugate, parameters, as well as q-Hermite and Rogers polynomials. It seems that this paper is one of the first papers that give a probabilistic interpretation of Rogers (continuous q-ultraspherical) polynomials.
description: 15 pages
A map of transcriptional heterogeneity and regulatory variation in human microglia.
Creators: name: Young, Adam M H
name: Kumasaka, Natsuhiko
name: Calvert, Fiona
name: Hammond, Timothy R
name: Knights, Andrew
name: Panousis, Nikolaos
name: Park, Jun Sung
name: Schwartzentruber, Jeremy
name: Liu, Jimmy
name: Kundu, Kousik
name: Segel, Michael
name: Murphy, Natalia A
name: McMurran, Christopher E
name: Bulstrode, Harry
name: Correia, Jason
name: Budohoski, Karol P
name: Joannides, Alexis
name: Guilfoyle, Mathew R
name: Trivedi, Rikin
name: Kirollos, Ramez
name: Morris, Robert
name: Garnett, Matthew R
name: Timofeev, Ivan
name: Jalloh, Ibrahim
name: Holland, Katherine
name: Mannion, Richard
name: Mair, Richard
name: Watts, Colin
name: Price, Stephen J
name: Kirkpatrick, Peter J
name: Santarius, Thomas
name: Mountjoy, Edward
name: Ghoussaini, Maya
name: Soranzo, Nicole
name: Bayraktar, Omer A
name: Stevens, Beth
name: Hutchinson, Peter J
name: Franklin, Robin J M
name: Gaffney, Daniel J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021

description: Microglia, the tissue-resident macrophages of the central nervous system (CNS), play critical roles in immune defense, development and homeostasis. However, isolating microglia from humans in large numbers is challenging. Here, we profiled gene expression variation in primary human microglia isolated from 141 patients undergoing neurosurgery. Using single-cell and bulk RNA sequencing, we identify how age, sex and clinical pathology influence microglia gene expression and which genetic variants have microglia-specific functions using expression quantitative trait loci (eQTL) mapping. We follow up one of our findings using a human induced pluripotent stem cell-based macrophage model to fine-map a candidate causal variant for Alzheimer's disease at the BIN1 locus. Our study provides a population-scale transcriptional map of a critically important cell for human CNS development and disease.
A phenomenological analysis of antiproton interactions at low energies
Creators: name: Bianconi, A.
name: Bonomi, G.
name: Bussa, M. P.
name: Rizzini, E. Lodi
name: Venturelli, L.
name: Zenoni, A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present an optical potential analysis of the antiproton-proton interactions at low energies. Our optical potential is purely phenomenological, and has been parametrized on data recently obtained by the Obelix Collaboration at momenta below 180 MeV/c. It reasonably fits annihilation and elastic data below 600 MeV/c, and allows us for an evaluation of the elastic cross section and rho-parameter down to zero kinetic energy. Moreover we show that the mechanism that depresses antiproton-nucleus annihilation cross sections at low energies is present in antiproton-proton interactions too.
description: 10 pages, 4 figures
Mechanisms Underlying Disorders of Consciousness: Bridging Gaps to Move Toward an Integrated Translational Science
Creators: name: Luppi, Andrea I.
name: Cain, Joshua
name: Spindler, Lennart R. B.
name: Górska, Urszula J.
name: Toker, Daniel
name: Hudson, Andrew E.
name: Brown, Emery N.
name: Diringer, Michael N.
name: Stevens, Robert D.
name: Massimini, Marcello
name: Monti, Martin M.
name: Stamatakis, Emmanuel A.
name: Boly, Melanie
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: The Curing Coma Campaign
Brain injury
Coma
Consciousness
Electroencephalography
Magnetic resonance imaging
Neuroimaging
Mechanism

description: Funder: Tiny Blue Dot Foundation
description: Funder: Templeton World Charity Foundation; doi: http://dx.doi.org/10.13039/501100011730
description: Funder: Cambridge Commonwealth, European and International Trust; doi: http://dx.doi.org/10.13039/501100003343
description: Funder: Gates Cambridge Trust; doi: http://dx.doi.org/10.13039/501100005370
description: Abstract: Aim: In order to successfully detect, classify, prognosticate, and develop targeted therapies for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic understanding of how severe brain injuries result in these disorders. Methods: To address this need, the Curing Coma Campaign convened a Mechanisms Sub-Group of the Coma Science Work Group (CSWG), aiming to identify the most pressing knowledge gaps and the most promising approaches to bridge them. Results: We identified a key conceptual gap in the need to differentiate the neural mechanisms of consciousness per se, from those underpinning connectedness to the environment and behavioral responsiveness. Further, we characterised three fundamental gaps in DOC research: (1) a lack of mechanistic integration between structural brain damage and abnormal brain function in DOC; (2) a lack of translational bridges between micro- and macro-scale neural phenomena; and (3) an incomplete exploration of possible synergies between data-driven and theory-driven approaches. Conclusion: In this white paper, we discuss research priorities that would enable us to begin to close these knowledge gaps. We propose that a fundamental step towards this goal will be to combine translational, multi-scale, and multimodal data, with new biomarkers, theory-driven approaches, and computational models, to produce an integrated account of neural mechanisms in DOC. Importantly, we envision that reciprocal interaction between domains will establish a “virtuous cycle,” leading towards a critical vantage point of integrated knowledge that will enable the advancement of the scientific understanding of DOC and consequently, an improvement of clinical practice.
Adaptive Fuzzy Throttle Control for an All Terrain Vehicle
Creators: name: Ashitey  Trebi-Ollennu
name: Dolan, John M.
Publisher: name: Carnegie Mellon University
Year: 1999
Subjects: subject: 80101 Adaptive Agents and Intelligent Robotics
subject: FOS: Computer and information sciences

description: This paper describes an adaptive fuzzy throttle control for an All Terrain Vehicle (ATV) powered by internal combustion engine. The design objective is to provide smooth throttle movement, zero steady-state speed error, and to maintain a selected vehicle speed over varying road slopes for a 2MPH to 30MPH speed range. Unlike modern production vehicles which have microprocessor based engine management systems, the ATV’s engine is mechanically controlled via a carburetor. A complete mathematical model of the engine is not available making it very difficult to apply convention control techniques. Using experience and data collected from extensive experiments conducted on the ATV throttle mechanism, an adaptive fuzzy throttle control algorithm is designed. A candidate Lyapunov function is employed in the adaptive law synthesis to ensure convergence. Experimental results are presented showing the effectiveness of the control algorithm at speeds below 2.74MPH (1.2m/s).
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0302
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0302, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0302, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: http://www.wikidata.org/entity/Q15945019
description: Provenance: abbaye Saint-Étienne de Dijon
Gauge and Yukawa Unification in Models with Gauge-Mediated Supersymmetry Breaking
Creators: name: Bagger, Jonathan A.
name: Matchev, Konstantin T.
name: Pierce, Damien M.
name: Zhang, Ren-Jie
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We examine gauge and Yukawa coupling unification in models with gauge-mediated supersymmetry breaking. We work consistently to two-loop order, and include all weak, messenger and unification-scale threshold corrections. We find that successful unification requires unification-scale threshold corrections that are in conflict with the minimal SU(5) model, but are consistent with the modified missing doublet SU(5) model for small tan beta, and large tan beta with mu>0.
description: 9 pages, 2 figures, published version
SEISMIC ANALYSIS OF INTZE TYPE ELEVATED SERVICE RESERVOIR USING DIFFERENT METHODS- Analysis backup data
Creators: name: Patil, Ravindra
name: Khatavkar, Pallavi
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 400509
subject: Structural dynamics
classificationCode: 400510
subject: Structural engineering

description: Water is basic need of every creation. Water supply scheme in each village and city needed with elevated service reservoir (ESR) for distribution of water with gravity. Water is importance during disaster like earthquake, tsunami etc. The elevated service reservoirs are essential part of the water supply schemes in the various part of the world. Intze type of water tank has economical design for large capacity of water storage. In this paper, seismic analysis of Intze tank for a given capacity are presented for two ratios of height to diameter, viz. H = 1/3 D and H = 2/3 D.The seismic analysis of tank with staging is presented here briefly. Two cases are studied by doing seismic analysis by three methods. 1. Linear Static Analysis, 2. Response Spectrum Analysis 3. Linear Time History Analysis. Final results are compared and concluded.It is observed that the shallower tank with H=1/3D having more stability among the two cases considered. Base shear in time history analysis is more and in response spectrum method is less as compared to IS 1893-part 2 method.
Simulating Dirac Hamiltonian in Curved Space-time by Split-step Quantum Walk
Creators: name: Mallick, Arindam
name: Mandal, Sanjoy
name: Karan, Anirban
name: Chandrashekar, C. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Dirac particle represents a fundamental constituent of our nature. Simulation of Dirac particle dynamics by a controllable quantum system using quantum walks will allow us to investigate the non-classical nature of dynamics in its discrete form. In this work, starting from a modified version of one-spatial dimensional general inhomogeneous split-step discrete quantum walk we derive an effective Hamiltonian which mimics a single massive Dirac particle dynamics in curved $(1+1)$ space-time dimension coupled to $U(1)$ gauge potential---which is a forward step towards the simulation of the unification of electromagnetic and gravitational forces in lower dimension and at the single particle level. Implementation of this simulation scheme in simple qubit-system has been demonstrated. We show that the same Hamiltonian can represent $(2+1)$ space-time dimensional Dirac particle dynamics when one of the spatial momenta remains fixed. We also discuss how we can include $U(N)$ gauge potential in our scheme, in order to capture other fundamental force effects on the Dirac particle. The emergence of curvature in the two-particle split-step quantum walk has also been investigated while the particles are interacting through their entangled coin operations.
description: Published version, 39 pages, 5 figures
Tracking interfacial single-molecule pH and binding dynamics via vibrational spectroscopy.
Creators: name: Huang, Junyang
name: Grys, David-Benjamin
name: Griffiths, Jack
name: De Nijs, Bart
name: Kamp, Marlous
name: Lin, Qianqi
name: Baumberg, Jeremy J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021

description: Understanding single-molecule chemical dynamics of surface ligands is of critical importance to reveal their individual pathways and, hence, roles in catalysis, which ensemble measurements cannot see. Here, we use a cascaded nano-optics approach that provides sufficient enhancement to enable direct tracking of chemical trajectories of single surface-bound molecules via vibrational spectroscopy. Atomic protrusions are laser-induced within plasmonic nanojunctions to concentrate light to atomic length scales, optically isolating individual molecules. By stabilizing these atomic sites, we unveil single-molecule deprotonation and binding dynamics under ambient conditions. High-speed field-enhanced spectroscopy allows us to monitor chemical switching of a single carboxylic group between three discrete states. Combining this with theoretical calculation identifies reversible proton transfer dynamics (yielding effective single-molecule pH) and switching between molecule-metal coordination states, where the exact chemical pathway depends on the intitial protonation state. These findings open new domains to explore interfacial single-molecule mechanisms and optical manipulation of their reaction pathways.
Water Ice in 2060 Chiron and its Implications for Centaurs and Kuiper Belt Objects
Creators: name: Luu, J. X.
name: Jewitt, D. C.
name: Trujillo, C.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the detection of water ice in the Centaur 2060 Chiron, based on near-infrared spectra (1.0 - 2.5 micron) taken with the 3.8-meter United Kingdom Infrared Telescope (UKIRT) and the 10-meter Keck Telescope. The appearance of this ice is correlated with the recent decline in Chiron's cometary activity: the decrease in the coma cross-section allows previously hidden solid-state surface features to be seen. We predict that water ice is ubiquitous among Centaurs and Kuiper Belt objects, but its surface coverage varies from object to object, and thus determines its detectability and the occurrence of cometary activity.
description: 18 pages, 3 figures, accepted by ApJ Letters
Adaptive Fuzzy Throttle Control for an All Terrain Vehicle
Creators: name: Ashitey  Trebi-Ollennu
name: Dolan, John M.
name: Khosla, Pradeep K.
Publisher: name: Carnegie Mellon University
Year: 1999
Subjects: subject: 80101 Adaptive Agents and Intelligent Robotics
subject: FOS: Computer and information sciences

description: This paper describes an adaptive fuzzy throttle control for an All Terrain Vehicle (ATV) powered by an internal combustion engine. The design objective is to provide smooth throttle movement and zero steadystate speed error, and to maintain a selected vehicle speed over varying road slopes for a 2MPH to 30MPH speed range. Using experience and data collected from extensive experiments conducted on the ATV throttle mechanism, an adaptive fuzzy throttle control algorithm is designed. A candidate Lyapunov function is employed in the adaptive law synthesis to ensure convergence. Experimental results are presented showing the effectiveness of the control algorithm at speeds below 2.74MPH (1.2m/s).
Evidence for an X-ray Emitting Galactic Bulge: Shadows Cast by Distant Molecular Gas
Creators: name: Park, Sangwook
name: Finley, John P.
name: Snowden, Steven L.
name: Dame, Thomas M.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A mosaic of 7 ROSAT PSPC pointed observations in the direction of (l,b ~ 10,0 deg) reveals deep X-ray shadows in the 0.5-2.0 keV band cast by dense molecular gas. The comparison between the observed on-cloud and off-cloud X-ray fluxes indicates that ~43% of the diffuse X-ray background in this direction in both the 3/4 keV and 1.5 keV bands originates behind the molecular gas, which is located at 2-4 kpc from the Sun. Given the short mean free path of X-rays in the 3/4 keV band in the Galactic plane (~1 kpc assuming an average space density of 1 cm^-3), this large percentage of the observed flux which originates beyond the molecular gas most likely indicates a strong enhancement in the distribution of X-ray emitting gas in the Galactic center region, possibly associated with a Galactic X-ray bulge.
description: 16 pages LaTex, 2 figures. Accepted for the publication in Astrophysical Journal, Letters
Ground states of the Wick-Cutkosky model using light-front dynamics
Creators: name: Cooke, Jason R.
name: Miller, Gerald A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We consider the ground state in a model with scalar nucleons and a meson using the formalism of light-front dynamics. Light-front potentials for two-nucleon bound states are calculated using two approaches. First, light-front time-ordered perturbation theory is used to calculate one- and two-meson-exchange potentials. These potentials give results that agree well with the ladder and ladder plus crossed box Bethe-Salpeter spectra. Secondly, approximations that incorporate non-perturbative physics are used to calculate alternative one-meson-exchange potentials. These non-perturbative potentials give better agreement with the spectra of the full non-perturbative ground-state calculation than the perturbative potentials. For lightly-bound states, all of the approaches appear to agree with each other.
description: 36 pages and 6 figures; corrected typos, added references
Investigating natural plant products as potential inhibitors to disrupt NS1 β-roll domain polymerisation in DENV2: a detailed computational chemistry approach
Creators: name: Paul, Tanwi
name: Roy, Alankar
name: Paul, Ishani
name: Banerjee, Prantik
name: Ray, Sujay
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: The aim of this investigation is to design a novel drug, screened through various computational methods, that harnesses the historical evidence of plant products inhibiting viral infections. The beta-roll domain of Flavivirus NS1, crucial for its stability, membrane interaction and viral RNA replication, underscores its significance in disease pathogenesis, being the sole non-structural protein detected in the sera of DENV-infected patients. Our goal is to develop optimised compounds that disrupt NS1 β-roll domain polymerisation, mitigating hydrophobic core formation, to effectively inhibit DENV2 cytopathic infection by leveraging natural interference with viral replication. We created 10 plant-based ligand libraries and applied scaffold hopping and bioisosteric replacement to improve them. Computational methodologies, including virtual screening, molecular dynamics simulation, contact matrix and dynamic cross correlation matrix, were employed for analysing the dynamics of the protein with the association of ligand. ADMET analysis of ligand 126 revealed a favourable ADME profile with no observed toxicity properties. Calculations of pKd, pKi and pIC50 values indicated a heightened affinity of the ligand for the receptor protein, suggesting enhanced inhibitory action and a reduced dissociation rate. These encouraging findings suggest a greater potency of the drug, warranting further in vitro testing for validation.
Stepwise Conformational Stabilization of a HIV-1 Clade C Consensus Envelope Trimer Immunogen Impacts the Profile of Vaccine-Induced Antibody Responses
Creators: name: Hauser, Alexandra
name: Carnell, George
name: Held, Kathrin
name: Sulbaran, Guidenn
name: Tischbierek, Nadine
name: Rogers, Lisa
name: Pollakis, Georgios
name: Tonks, Paul
name: Hoelscher, Michael
name: Ding, Song
name: Sanders, Rogier W.
name: Geldmacher, Christof
name: Sattentau, Quentin
name: Weissenhorn, Winfried
name: Heeney, Jonathan L.
name: Peterhoff, David
name: Wagner, Ralf
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: HIV vaccine
envelope
stabilized trimer
clade C
consensus
centralized sequence
immunization
immunogen design
antibody response
peptide microarray

description: Stabilization of the HIV-1 Envelope glycoprotein trimer (Env) in its native pre-fusion closed conformation is regarded as one of several requirements for the induction of neutralizing antibody (nAb) responses, which, in turn, will most likely be a prerequisite for the development of an efficacious preventive vaccine. Here, we systematically analyzed how the stepwise stabilization of a clade C consensus (ConC) Env immunogen impacts biochemical and biophysical protein traits such as antigenicity, thermal stability, structural integrity, and particle size distribution. The increasing degree of conformational rigidification positively correlates with favorable protein characteristics, leading to optimized homogeneity of the protein preparations, increased thermal stability, and an overall favorable binding profile of structure-dependent broadly neutralizing antibodies (bnAbs) and non-neutralizing antibodies (non-nAbs). We confirmed that increasing the structural integrity and stability of the Env trimers positively correlates with the quality of induced antibody responses by the immunogens. These and other data contribute to the selection of ConCv5 KIKO as novel Env immunogens for use within the European Union’s H2020 Research Consortium EHVA (European HIV Alliance) for further preclinical analysis and phase 1 clinical development.
Anomalous low-temperature enhancement of supercurrent in topological-insulator nanoribbon Josephson junctions: evidence for low-energy Andreev bound states
Creators: name: Kayyalha, Morteza
name: Kargarian, Mehdi
name: Kazakov, Aleksandr
name: Miotkowski, Ireneusz
name: Galitski, Victor M.
name: Yakovenko, Victor M.
name: Rokhinson, Leonid P.
name: Chen, Yong P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report anomalous enhancement of the critical current at low temperatures in gate-tunable Josephson junctions made from topological insulator BiSbTeSe$_2$ nanoribbons with superconducting Nb electrodes. In contrast to conventional junctions, as a function of the decreasing temperature $T$, the increasing critical current $I_c$ exhibits a sharp upturn at a temperature $T_*$ around 20$\%$ of the junction critical temperatures for several different samples and various gate voltages. The $I_c$ vs. $T$ demonstrates a short junction behavior for $T>T_*$, but crosses over to a long junction behavior for $T