cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Der Stellenwert der PSA-Dichte in Kombination mit PIRADS für die Tumorprädiktion des Prostatakarzinoms in der Prostatastanzbiopsie
Creators: name: Distler, F.A.
name: Radtke, J.P.
name: Bonekamp, D.
name: Kesch, C.
name: Schlemmer, H.-P.
name: Wieczorek, K.
name: Hohenfellner, M.
name: Hadaschik, B.A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die multiparametrische MRT (mpMRT) hat einen zunehmenden Stellenwert in der Prostatakarzinom(PC)-Diagnostik. Sie verbessert die PC-Detektion und kann theoretisch helfen, die Überdiagnose von insignifikanten PC durch weniger entnommene Stanzzylinder zu reduzieren. Unsere Hypothese ist[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie
title: Gesundheitszustand 45-jähriger Männer am Beispiel erfolgter Prostatakarzinom-Vorsorgeuntersuchungen
Creators: name: Frank, J.
name: Laenger, N.
name: Klorek, T.
name: Schulwitz, H.
name: Albers, P.
name: Arsov, C.
name: Kuczyk, M.
name: Imkamp, F.
name: Hadaschik, B.
name: Hohenfellner, M.
name: Gschwend, J.E.
name: Herkommer, K.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung: Laut Empfehlungen der S3-Leitlinie sollen Männer ab dem 45. Lebensjahr über die Prostatakarzinom Früherkennung informiert werden. In vorliegendem Begleitprojekt wurden 45-jährige Männer zu bereits erfolgten Vorsorgeuntersuchungen (PSA/DRU) durch Urologen/andere[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie
title: Assoziation zwischen PSA-Wert und Familienanamnese im 45-jährigen Kollektiv der deutschen Prostatakarzinom Screening Studie (PROBASE)
Creators: name: Baade, N.
name: Länger, N.
name: Klorek, T.
name: Grill, S.
name: Schulwitz, H.
name: Albers, P.
name: Arsov, C.
name: Hadaschik, B.
name: Hohenfellner, M.
name: Imkamp, F.
name: Kuczyk, M.
name: Gschwend, J.
name: Herkommer, K.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung: Studien zeigten, dass der Diagnose-PSA-Wert bei Patienten mit positiver Prostatakarzinom-Familienanamnese (PC-FA) tendenziell niedriger ist. In einem einzigartigen 45-jährigen deutschen Screening-Kollektiv mit mehr als 5.000 Probanden wurde der Zusammenhang zwischen PC-FA und der[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie
Discovery of a very weak magnetic field on the Am star Alhena
Creators: name: Blazère, Aurore
name: Neiner, Coralie
name: Petit, Pascal
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Alhena ($γ$ Gem) was observed in the frame of the BRITE (BRIght Target Explorer) spectropolarimetric survey, which gathers high resolution, high signal-to-noise, high sensitivity, spectropolarimetric observations of all stars brighter than V=4 to combine seismic and spectropolarimetric studies of bright stars. We present here the discovery of a very weak magnetic field \textbf{on} the Am star Alhena, thanks to very high signal-to-noise spectropolarimetric data obtained with Narval at Télescope Bernard Lyot (TBL). All previously studied Am stars show the presence of ultra-weak (sub-Gauss) fields with Zeeman signatures with an unexpected prominent positive lobe. However, Alhena presents a slightly stronger (but still very weak, only a few Gauss) field with normal Zeeman signatures with a positive and negative lobe, as found in stronger field (hundreds or thousands of Gauss) stars. It is the first detection of a normal magnetic signature in an Am star. Alhena is thus a very interesting object, which might provide the clue to understanding the peculiar shapes of the magnetic signatures of the other Am stars.
description: letter accepted by MNRAS
Anomalous gap edge dissipation in disordered superconductors on the brink of localization
Creators: name: Cheng, Bing
name: Wu, Liang
name: Laurita, N. J.
name: Singh, Harkirat
name: Chand, Madhavi
name: Raychaudhuri, Pratap
name: Armitage, N. P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Superconductivity in disordered systems close to an incipient localization transition has been an area of investigation for many years. It has been noted that in such highly disordered superconductors, anomalous spectral weight develops in their conductivity near and below the superconducting gap energy. In this work we investigate the low frequency conductivity in disordered superconducting NbN thin films close to the localization transition with time-domain terahertz spectroscopy. In the normal state, strong deviations from the Drude form due to incipient localization are found. In the superconducting state we find substantial spectral weight at frequencies well below the superconducting gap scale derived from tunneling. We analyze this spectral weight in the context of a model of disorder induced broadening of the quasiparticle density of states and effective pair-breaking. We find that although aspects of the optical and tunneling data can be consistently modeled in terms of this effect of mesoscopic disorder, the optical conductivity returns to the normal state value much faster than any model predicts. This points to the non-trivial interplay of superconductivity and disorder close to localization.
description: 5 pages, 3 figures in main text; 7 pages, 4 figures in SI
Dibaryons with two strange quarks and total spin zero in a constituent quark model
Creators: name: Park, Woosung
name: Park, Aaron
name: Lee, Su Houng
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We investigate the symmetry property and construct the wave function of the dibaryon states containing two strange quarks with S=0 in both the flavor SU(3) symmetric and breaking cases. We discuss how the color $\otimes$ isospin $\otimes$ spin states of dibaryon in the symmetry broking case of flavor SU(3) can be extracted from the fully antisymmetric states in flavor SU(3). The stability of the dibaryon against the strong decay into two baryons are then discussed, by using the variational method within a constituent quark model with a confining and color-spin interactions. To compare our results with that from lattice QCD in flavor SU(3) limit, we search for the stable H-dibaryon in a wide range of $π$ meson mass. We find that with the given potential, there is no compact six quark dibaryon state in the SU(3) flavor symmetry broken case with realistic quark masses as well as in flavor SU(3) symmetric case in a wide range of quark masses.
description: 22pages, 2figures
Investigating the role of matrix and integrase in the nuclear import of the HIV-1 genome
Creators: name: Hearps., Anna C.
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Regularizing properties of Complex Monge-Ampère flows
Creators: name: Tô, Tat Dat
Publisher: name: arXiv
Year: 2016
Subjects: subject: Complex Variables (math.CV)
subject: Analysis of PDEs (math.AP)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We study the regularizing properties of complex Monge-Ampère flows on a Kähler manifold $(X,ω)$ when the initial data are $ω$-psh functions with zero Lelong number at all points. We prove that the general Monge-Ampère flow has a solution which is immediately smooth. We also prove the uniqueness and stability of solution.
description: 30 pages
Surprises in astrophysical gasdynamics
Creators: name: Balbus, Steven A.
name: Potter, WIlliam J.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Much of astrophysics consists of the study of ionised gas under the influence of gravitational and magnetic fields. Thus, it is not possible to understand the astrophysical universe without a detailed knowledge of the dynamics of magnetised fluids. Fluid dynamics is, however, a notoriously tricky subject, in which it is all too easy for one's a priori intuition to go astray. In this review, we seek to guide the reader through a series of illuminating yet deceptive problems, all with an enlightening twist. We cover a broad range of topics including the instabilities acting in accretion discs, the hydrodynamics governing the convective zone of the Sun, the magnetic shielding of a cooling galaxy cluster, and the behaviour of thermal instabilities and evaporating clouds. The aim of this review is to surprise and intrigue even veteran astrophysical theorists with an idiosynchratic choice of problems and counterintuitive results. At the same time, we endeavour to bring forth the fundamental ideas, to set out important assumptions, and to describe carefully whatever novel techniques may be appropriate to the problem at hand. By beginning at the beginning, and analysing a wide variety of astrophysical settings, we seek not only to make this review suitable for fluid dynamic veterans, but to engage novice recruits as well with what we hope will be an unusual and instructive introduction to the subject.
description: 68 pages, 8 figures, to appear in Rep. Prog. Phys
A question mark on the equivalence of Einstein and Jordan frames
Creators: name: Banerjee, Narayan
name: Majumder, Barun
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: With an explicit example, we show that Jordan frame and the conformally transformed Einstein frames clearly lead to different physics for a non-minimally coupled theory of gravity, namely Brans-Dicke theory, at least at the quantum level. The example taken up is the spatially flat Friedmann cosmology in Brans-Dicke theory.
description: 6 pages, 4 figures. Online in Phys Lett B
10 Schritte für mehr Openness in Ihrer Bibliothek
Creators: name: Lohmeier, Felix
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: Openness
subject: Open Access
subject: Checkliste
subject: Empfehlungen
subject: 000

description: Bibliotheken stehen traditionell für den freien Zugang zum Wissen. Dieses Prinzip erlebt in der digitalen Welt mit Open Access, Open Source und Open Data seit Jahren eine Renaissance. Kaum eine Bibliothek, die sich nicht öffentlich dafür einsetzt. Und dennoch mangelt es oft an der nötigen Konsequenz, denn BibliothekarInnen werben beispielsweise am Campus für Open Access, publizieren aber selbst oft genug noch in Zeitschriften, die nicht unter einer freien Lizenz stehen. Im Vortrag werden 10 praktikable Schritte für mehr Openness vorgestellt, die interessierte Bibliotheken als Checkliste für sich nutzen können.
Exploring and sharing Australian Indigenous narratives
Creators: name: Hamilton, Ian Robert
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: Previously, I completed a library project which focused on preserving the knowledge available within the Central Gippsland Indigenous community. This thesis extends this work following input from a range of Indigenous people who offered historical and other culturally related knowledge. Early Australian colonisation condemned much of this knowledge via relevant literature and also from general society. Twelve different Australian Indigenous people from central Gippsland and Queensland provided audio narratives that helped investigate the associated learning potential. Examples include historical events, artistry and various community activities. Community Based Participatory Research was selected as a way of asking for help rather than demanding information. In this way, I acknowledge some of the difficulties experienced by Australian Indigenous people when interacting with mainstream activities. Digital audio recordings have been used to preserve narratives whilst recognising and respecting oral history methods. Unstructured qualitative interviews by participants have provided a broad range of information. The data analysis explores various stages of the data collection process. The conclusion describes research benefits, limits and future work as well as also individually recognising each person as part of the participant community. The major focus of the project is the resultant learning which was assessed as a result of the narrative analysis and also the general research process.
Synthesis, characterization, and application in rechargeable batteries of CuxS-rGO aerogels
Creators: name: Bernechea, María
name: Yanhan Li
name: Xiaodong Shen
name: Aina, Sergio
name: M. Pilar Lobera
name: Vinzintin, Alen
name: Dominko, Robert
Publisher: name: Zenodo
Year: 2022

description: Flash oral presentation from María Bernechea at XXXVIII Bienial Conference of RSEQ 2022. Granada 27 - 30 June 2022
Fast reconnection in relativistic plasmas: the magnetohydrodynamics tearing instability revisited
Creators: name: Del Zanna, L.
name: Papini, E.
name: Landi, S.
name: Bugli, M.
name: Bucciantini, N.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Fast reconnection operating in magnetically dominated plasmas is often invoked in models for magnetar giant flares, for magnetic dissipation in pulsar winds, or to explain the gamma-ray flares observed in the Crab nebula, hence its investigation is of paramount importance in high-energy astrophysics. Here we study, by means of two dimensional numerical simulations, the linear phase and the subsequent nonlinear evolution of the tearing instability within the framework of relativistic resistive magnetohydrodynamics, as appropriate in situations where the Alfven velocity approaches the speed of light. It is found that the linear phase of the instability closely matches the analysis in classical MHD, where the growth rate scales with the Lundquist number S as S^-1/2, with the only exception of an enhanced inertial term due to the thermal and magnetic energy contributions. In addition, when thin current sheets of inverse aspect ratio scaling as S^-1/3 are considered, the so-called "ideal" tearing regime is retrieved, with modes growing independently on S and extremely fast, on only a few light crossing times of the sheet length. The overall growth of fluctuations is seen to solely depend on the value of the background Alfven velocity. In the fully nonlinear stage we observe an inverse cascade towards the fundamental mode, with Petschek-type supersonic jets propagating at the external Alfven speed from the X-point, and a fast reconnection rate at the predicted value R~(ln S)^-1.
description: 14 pages, 9 figures, accepted for publication (MNRAS)
Enriching Ontologies with Encyclopedic Background Knowledge for Document Indexing
Creators: name: Posch, Lisa
Publisher: name: arXiv
Year: 2016
Subjects: subject: Digital Libraries (cs.DL)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: The rapidly increasing number of scientific documents available publicly on the Internet creates the challenge of efficiently organizing and indexing these documents. Due to the time consuming and tedious nature of manual classification and indexing, there is a need for better methods to automate this process. This thesis proposes an approach which leverages encyclopedic background knowledge for enriching domain-specific ontologies with textual and structural information about the semantic vicinity of the ontologies' concepts. The proposed approach aims to exploit this information for improving both ontology-based methods for classifying and indexing documents and methods based on supervised machine learning.
The role of central monoaminergic pathways in cardiovascular control
Creators: name: Head., Geoffrey Albert
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
title: Single-incision laparoscopic liver resection (SILL) – advantages and challanges in left lateral sectionectomy
Creators: name: Schmelzle, Moritz
name: Seehofer, Daniel
name: Pratschke, Johann
name: Zorron, Ricardo
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Multi-incision laparoscopic liver resection (MILL) has become technically feasible and safe. Thus, MILL is favored by most experienced hepatobiliary centers for sectionectomy and hemihepatectomy in patients with lesions and benign tumors. Potential advantages over multi-incision laparoscopy[for full text, please go to the a.m. URL]
description: 133. Kongress der Deutschen Gesellschaft für Chirurgie
Instance Influence Estimation for Hyperspectral Target Signature Characterization using Extended Functions of Multiple Instances
Creators: name: Zou, Sheng
name: Zare, Alina
Publisher: name: arXiv
Year: 2016
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The Extended Functions of Multiple Instances (eFUMI) algorithm is a generalization of Multiple Instance Learning (MIL). In eFUMI, only bag level (i.e. set level) labels are needed to estimate target signatures from mixed data. The training bags in eFUMI are labeled positive if any data point in a bag contains or represents any proportion of the target signature and are labeled as a negative bag if all data points in the bag do not represent any target. From these imprecise labels, eFUMI has been shown to be effective at estimating target signatures in hyperspectral subpixel target detection problems. One motivating scenario for the use of eFUMI is where an analyst circles objects/regions of interest in a hyperspectral scene such that the target signatures of these objects can be estimated and be used to determine whether other instances of the object appear elsewhere in the image collection. The regions highlighted by the analyst serve as the imprecise labels for eFUMI. Often, an analyst may want to iteratively refine their imprecise labels. In this paper, we present an approach for estimating the influence on the estimated target signature if the label for a particular input data point is modified. This "instance influence estimation" guides an analyst to focus on (re-)labeling the data points that provide the largest change in the resulting estimated target signature and, thus, reduce the amount of time an analyst needs to spend refining the labels for a hyperspectral scene. Results are shown on real hyperspectral sub-pixel target detection data sets.
description: Published, Proceedings of the SPIE, 2016
title: Chromogranin A and neuron-specific enolase serum levels as predictors of treatment outcome in metastatic castration-resistant prostate cancer patients under abiraterone therapy
Creators: name: Heck, M.M.
name: Thaler, M.
name: Schmid, S.C.
name: Seitz, A.-K.
name: Tauber, R.
name: Kübler, H.
name: Maurer, T.
name: Thalgott, M.
name: Hatzchristodoulou, G.
name: Höppner, M.
name: Nawroth, R.
name: Luppa, P.
name: Gschwend, J.E.
name: Retz, M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Objective: Neuroendocrine differentiation is a potential mechanism of treatment resistance to novel systemic therapies targeting the androgen-receptor in metastatic castration-resistant prostate cancer (mCRPC). To determine the impact of elevated neuroendocrine serum markers on treatment outcome under[for full text, please go to the a.m. URL]
description: 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie
title: Prognostic value of surgeons experience in patients undergoing radical cystectomy for urothelial carcinoma: results of a single center study
Creators: name: Grimm, T.
name: Buchner, A.
name: Schneevoigt, B.-S.
name: Kretschmer, A.
name: Apfelbeck, M.
name: Grabbert, M.T.
name: Jokisch, F.
name: Schulz, G.
name: Stief, C.G.
name: Karl, A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Introduction and objectives: Performing a radical cystectomy (RC) is a challenging procedure with a long learning curve. There is only limited knowledge about the prognostic relevance of a surgeon's individual level of skill in practicing RC for urothelial carcinoma (UC). In this study we analyzed[for full text, please go to the a.m. URL]
description: 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie
Implementing ‘Mantle of the Expert’ in Indonesian Senior and Vocational High Schools
Creators: name: Sitti Fatimah
Publisher: name: Monash University
Year: 2016
Subjects: subject: 200303 English as a Second Language
subject: FOS: Languages and literature
subject: 130106 Secondary Education
subject: FOS: Educational sciences

description: This study explores the implementation of Mantle of the Expert (MoE) as a drama-based approach to English instruction within three Indonesian senior and vocational high schools. It investigates the experience of the implementation among teachers and students and highlights the potential benefits for the teaching and learning processes.

 The study was constructivist in orientation and adopted a qualitative approach. A multiple case study presents three accounts of implementation in three school settings. I conducted a MoE workshop for teacher participants to introduce the MoE concept. Thereafter, a series of interviews prior to, during and post implementation were conducted with each teacher participant. This was augmented by classroom observations and a questionnaire distributed to student participants in each classroom setting.

 Analysis within and across cases indicate the enactment of MoE elements and signal the the challenges and constraints experienced by the teachers which limited enactment. A number of positive outcomes emerged for both student and teacher participants. Overall, the study demonstrates that the principles of Process Drama, of which MoE is one approach, enhanced student engagement in learning through the construction of an imaginary context. Collaboration proved to be a powerful learning platform and it reduced students’ English speaking anxiety. The MoE approach encouraged student agency and their active and inquiry-based learning. For teachers, it introduced a new framework for their instructional practice and presented possibilities for their integration of language skills through connection to content across the curriculum that was learnt within real-world contexts.

 The study demonstrates the potential significance of MoE as a Process Drama approach for enhancing student engagement in English language teaching and learning. The approach aligns strongly with the principles of Communicative Language Teaching (CLT) and holds potential for the realisation of the goals of English for secondary schools as outlined in the School-Based Curriculum (SBC) in Indonesia.
Nitrogen-rich carbon for redox-active capacitor with a high-frequency response
Creators: name: Elżbieta Frąckowiak
name: Ślesiński, Adam
name: Piwek, Justyna
name: Fic, Krzysztof
name: Aina, Sergio
name: Vizintin, Alen
name: Blaz Tratnik
name: Tchernychova, Elena
name: M. Pilar Lobera
name: Dominko, Robert
name: Bernechea, María
Publisher: name: Zenodo
Year: 2022

description: Keynote presentation from Elżbieta Frąckowiak at Carbon 2022 Conference "Carbon for a Cleaner Future". London 3 - 8 July 2022
Gluon vs. Photon Production of a 750 GeV Diphoton Resonance
Creators: name: Csaki, Csaba
name: Hubisz, Jay
name: Lombardo, Salvator
name: Terning, John
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The production mechanism of a 750 GeV diphoton resonance, either via gluon or photon fusion, can be probed by studying kinematic observables in the diphoton events. We perform a detector study of the two production modes of a hypothetical scalar or tensor diphoton resonance in order to characterize the features of the two scenarios. The nature of the resonance production can be determined from the jet multiplicity, the jet and diphoton rapidities, the rate of central pseudorapidity gaps, or the possible detection of forward protons from elastic photoproduction for events in the signal region. Kinematic distributions for both signals and expected irreducible diphoton background events are provided for comparison along with a study of observables useful for distinguishing the two scenarios at an integrated luminosity of 20 fb$^{-1}$. We find that decay photons from a 750 GeV scalar resonance have a preference for acceptance in the central detector barrel, while background events are more likely to give accepted photons in the detector end caps. This disfavors the interpretation of the large number of excess events found by the the Run-2 CMS diphoton search with one photon detected in the end cap as a wide spin-0 resonance signal. However, one expects more end cap photons in the case of spin-2 resonance.
description: 14 pages, 15 figures
MAPK related phenotypic decisions in yeast
Creators: name: Jarzombek, Johann
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: 570
subject: 540

description: The evolutionarily conserved mitogen-activated protein kinase (MAPK) network is a signalling module, which enables the coordination and processing of various extracellular stimuli. It thereby guarantees a specific biological response to a precise dose of a given stimuli. The haploid yeast Saccharomyces cerevisiae uses this network to select particular mating partners by quantitatively interpreting the pheromone concentration gradient generated by potential mates. Activation of the mating MAPK module occurs only above a certain pheromone concentration threshold and relies on the pheromone-induced recruitment of a protein complex consisting of the scaffold Ste5 and the MAPKs Ste11, Ste7 and Fus3. This module ensures a robust morphological response in form of a mating projection to a defined pheromone concentration and allows cells to gauge the distance to a potential mating partner. Yet it remains unclear which of the module’s features interpret the pheromone concentration to decide when and where to generate a mating projection. To infer the network structure of the mating MAPK module, we developed a reverse engineering approach, which is based on the detection of pheromone response dependent changes in protein complex abundances. Interactions within the MAPK module were measured by fluorescence correlation spectroscopy (FCS), of which all possible protein-species in the MAPK module were resolved by applying a linear regression analysis (LRA). Using this approach, we were able to identify a cytosolic kinase-substrate interaction between Fus3 and the upstream Ste11, which constitutes a hitherto uncharacterized negative feedback. It affects the readout of the pheromone gradient and provides robustness to changes in the components involved in the loop. This negative feedback occurs by phosphorylation of S243 on Ste11 that hinders its binding to the scaffold Ste5 and thereby uncouples Ste11 from Fus3 activity. Controlling this mechanism provides ultrasensitivity at the first step of the MAPK cascade, as part of the hierarchical cascade arrangement, ensures a switch-like mating response and triggers shmoo formation at the right distance to a partner. This cytoplasmic feedback has a spatial component that confines the cytoplasmic Fus3 phosphorylation gradient. It thereby generates and maintains a localized source of active Fus3 at the mating tip, which in turn spatially restricts shmoo formation. This work shows how a network motif in the MAPK module enables the interpretation of the pheromone concentration gradient to sense potential mates, and how this extracellular gradient is translated into an intracellular activity gradient by spatial control of signalling, ultimately deciding both when and where to respond.
First-passage phenomena in hierarchical networks
Creators: name: Tavani, Flavia
name: Agliari, Elena
Publisher: name: arXiv
Year: 2016
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: In this paper we study Markov processes and related first passage problems on a class of weighted, modular graphs which generalize the Dyson hierarchical model. In these networks, the coupling strength between two nodes depends on their distance and is modulated by a parameter $σ$. We find that, in the thermodynamic limit, ergodicity is lost and the "distant" nodes can not be reached. Moreover, for finite-sized systems, there exists a threshold value for $σ$ such that, when $σ$ is relatively large, the inhomogeneity of the coupling pattern prevails and "distant" nodes are hardly reached. The same analysis is carried on also for generic hierarchical graphs, where interactions are meant to involve $p$-plets ($p>2$) of nodes, finding that ergodicity is still broken in the thermodynamic limit, but no threshold value for $σ$ is evidenced, ultimately due to a slow growth of the network diameter with the size.
Galactic cosmic rays on extrasolar Earth-like planets: II. Atmospheric implications
Creators: name: Grießmeier, J. --M.
name: Tabataba-Vakili, F.
name: Stadelmann, A.
name: Grenfell, J. L.
name: Atri, D.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: (abridged abstract) Theoretical arguments indicate that close-in terrestial exoplanets may have weak magnetic fields. As described in the companion article (Paper I), a weak magnetic field results in a high flux of galactic cosmic rays to the top of the planetary atmosphere. We investigate effects that may result from a high flux of galactic cosmic rays both throughout the atmosphere and at the planetary surface. Using an air shower approach, we calculate how the atmospheric chemistry and temperature change under the influence of galactic cosmic rays for Earth-like (N_2-O_2 dominated) atmospheres. We evaluate the production and destruction rate of atmospheric biosignature molecules. We derive planetary emission and transmission spectra to study the influence of galactic cosmic rays on biosignature detectability. We then calculate the resulting surface UV flux, the surface particle flux, and the associated equivalent biological dose rates. We find that up to 20% of stratospheric ozone is destroyed by cosmic-ray protons. The reduction of the planetary ozone layer leads to an increase in the weighted surface UV flux by two orders of magnitude under stellar UV flare conditions. The resulting biological effective dose rate is, however, too low to strongly affect surface life. We also examine the surface particle flux: For a planet with a terrestrial atmosphere, a reduction of the magnetic shielding efficiency can increase the biological radiation dose rate by a factor of two. For a planet with a weaker atmosphere (with a surface pressure of 97.8 hPa), the planetary magnetic field has a much stronger influence on the biological radiation dose, changing it by up to two orders of magnitude.
description: 14 pages, 9 figures, published in A&A
Pharmacological reactivity of the internal mammary artery and saphenous vein : implications for coronary artery bypass graft surgery
Creators: name: He., Guo-Wei
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
title: Erfolgreiche Kooperation im Kinderschutz
Creators: name: Beyerlein, Stefan
name: Maaß-Quast, Antje
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Wir möchten die Kooperation zwischen der Kinderschutzgruppe (KSG) der DRK Kinderklinik Siegen und der Ärztlichen Beratungsstelle gegen Vernachlässigung und Misshandlung von Kindern und Jugendlichen e.V. (ÄB) als erfolgreiches Modell einer fallbezogenen Zusammenarbeit [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 133. Kongress der Deutschen Gesellschaft für Chirurgie
The nature of the UV halo around the spiral galaxy NGC 3628
Creators: name: Baes, Maarten
name: Viaene, Sébastien
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Thanks to deep UV observations with GALEX and Swift, diffuse UV haloes have recently been discovered around galaxies. Based on UV-optical colours, it has been advocated that the UV haloes around spiral galaxies are due to UV radiation emitted from the disc and scattered off dust grains at high latitudes. Detailed UV radiative transfer models that take into account scattering and absorption can explain the morphology of the UV haloes, and they require the presence of an additional thick dust disc next the to traditional thin disc for half of the galaxies in their sample. We test whether such an additional thick dust disc agrees with the observed infrared emission in NGC 3628, an edge-on galaxy with a clear signature of a thick dust disc. We extend the far-ultraviolet radiative transfer models to full-scale panchromatic models. Our model, which contains no fine-tuning, can almost perfectly reproduce the observed spectral energy distribution from UV to mm wavelengths. These results corroborate the interpretation of the extended UV emission in NGC 3628 as scattering off dust grains, and hence of the presence of a substantial amount of diffuse extra-planar dust. A significant caveat, however, is the geometrical simplicity and non-uniqueness of our model: other models with a different geometrical setting could lead to a similar spectral energy distribution. More detailed radiative transfer simulations that compare the model results to images from UV to submm wavelengths are a way to break this degeneracy, as are UV polarisation measurements.
description: 6 pages, 2 figures, accepted for publication in Astronomy & Astrophysics
title: Uniparental Disomy (UPD) in somatic mosaic 45,X/ 46,XY/46,XX associated with disorders of Sex development
Creators: name: Serra, Alexandre
name: Henne-Bruns, Doris
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Disorders of Sex Development affect the development of chromosomal, gonadal and/or anatomic sex. We analyzed a patient with ambiguous genitalia aiming to correlate the genetic findings with the phenotype. Materials and methods: Blood and tissue samples from a male patient with penoscrotal[for full text, please go to the a.m. URL]
description: 133. Kongress der Deutschen Gesellschaft für Chirurgie
Shells, orbit bifurcations and symmetry restorations in Fermi systems
Creators: name: Magner, A. G.
name: Koliesnik, M. V.
name: Arita, K.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The periodic-orbit theory based on the improved stationary-phase method within the phase-space path integral approach is presented for the semiclassical description of the nuclear shell structure, concerning the main topics of the fruitful activity of V. G. Solovjov. We apply this theory to study bifurcations and symmetry breaking phenomena in a radial power-law potential which is close to the realistic Woods-Saxon one up to about the Fermi energy. Using the realistic parametrization of nuclear shapes we explain the origin of the double-humped fission barrier and the asymmetry in the fission isomer shapes by the bifurcations of periodic orbits. The semiclassical origin of the oblate-prolate shape asymmetry and tetrahedral shapes is also suggested within the improved periodic-orbit approach. The enhancement of shell structures at some surface diffuseness and deformation parameters of such shapes are explained by existence of the simple local bifurcations and new non-local bridge-orbit bifurcations in integrable and partially integrable Fermi systems. We obtained good agreement between the semiclassical and quantum shell-structure components of the level density and energy for several surface diffuseness and deformation parameters of the potentials, including their symmetry breaking and bifurcation values.
description: 57 pages, 34 figures
EMI-Immune Differential Wireline Communication Transceiver Front-Ends
Creators: name: Matig-A, Gilbert Andrew
Publisher: name: Monash University
Year: 2017
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Electromagnetic interference (EMI) presents a considerable challenge in wireline transmitter-receiver designs. In this age when electronic systems are continuously being miniaturized and multi-functionalized, conventional electromagnetic interference (EMI) suppression and mitigation solutions become more impractical as they require more space, additional components and an increase in the manufacturing costs and delay the development process. Thus, inherent EMI-self-immune designs become more desirable.
 Despite their differential signaling nature, differential wireline communication front-ends are one of the blocks that are primarily vulnerable to EMI due to the nonlinear properties of active devices used in integrated systems. Wireline communication front-end blocks are directly connected to electrically long transmission lines that act as good receptors of EMI. Consequently, data transmission errors become predominant as injected EMI corrupts transmitted data by causing unintended logic state reversals due to large amplitude excursions brought by the undesired injected signal. Additionally, an injected EMI causes severe DC shift errors, driving the front-end blocks out of their operating regions. Hence, EMI corrupts the integrity of an electronic system when it is not mitigated.
 The aim of this research is to eliminate the need for the costly off-chip EMI suppression and mitigation schemes by designing practical and efficient integrated EMI solutions that enable integrated wireline communication front-ends to have self--immunity to EMI. The study focused on three of the most commonly applied high-speed wireline communication systems – Low voltage differential signaling (LVDS), current mode logic (CML), and voltage mode logic (VML). Thus far, EMI self-immune LVDS, CML and VML transceiver systems have been designed and fabricated using standard UMC 0.18μm CMOS process. The proposed transceivers demonstrated a superior level of EMI robustness as compared to conventional transceiver structures when both are subjected to the full spectrum and worst case amplitude of EMI.
title: Surgical retrieval of a swallowed denture in a schizophrenic patient
Creators: name: Dörner, Johannes
name: Ambe, Peter
name: Spelter, Herbert
name: Zirngibl, Hubert
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Accidental foreign body ingestion is a common phenomenon in children between 6 months to 6 years of age. In adults, foreign body ingestion is commonly observed in the geriatric population and in patients with psychiatric disorders. Besides food bolus, fish and chicken bones, dentures represent[for full text, please go to the a.m. URL]
description: 133. Kongress der Deutschen Gesellschaft für Chirurgie
Nested Defects on the Boundary of Topological Superconductors
Creators: name: de Lisle, James
name: Palumbo, Giandomenico
name: Gangat, Adil. A.
name: Pachos, Jiannis K.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Helical Majorana edge states at the 2D boundaries of 3D topological superconductors can be gapped by a surface Zeeman field. Here we study the effect nested defects imprinted on the Zeeman field can have on the edge states. We demonstrate that depending on the configuration of the field we can induce dimensional reduction of gapless Majorana modes from 2D to 1D or quasi-0D at magnetic domain walls. We determine the nature of the Majorana localisation on these defects as a function of the magnitude and configuration of the Zeeman field. Finally, we observe a generalisation of the index theorem governing the number of gapless modes at the interface between topologically non-trivial systems with partial Chern numbers.
description: 11 pages, 9 figures
Spectral characterization and differential rotation study of active CoRoT stars
Creators: name: Nagel, Evangelos
name: Czesla, Stefan
name: Schmitt, Jürgen H. M. M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The CoRoT space telescope observed nearly 160 000 light curves. Among the most outstanding is that of the young, active planet host star CoRoT-2A. In addition to deep planetary transits, the light curve of CoRoT-2A shows strong rotational variability and a superimposed beating pattern. To study the stars that produce such an intriguing pattern of photometric variability, we identified a sample of eight stars with rotation periods between 0.8 and 11 days and photometric variability amplitudes of up to 7.5 %, showing a similar CoRoT light curve. We also obtained high-resolution follow-up spectroscopy with TNG/SARG and carried out a spectral analysis with SME and MOOG. We find that the color dependence of the light curves is consistent with rotational modulation due to starspots and that latitudinal differential rotation provides a viable explanation for the light curves, although starspot evolution is also expected to play an important role. Our MOOG and SME spectral analyses provide consistent results, showing that the targets are dwarf stars with spectral types between F and mid-K. Detectable Li i absorption in four of the targets confirms a low age of 100-400 Myr also deduced from gyrochronology. Our study indicates that the photometric beating phenomenon is likely attributable to differential rotation in fast-rotating stars with outer convection zones.
description: Accepted for publication by A&A
The influence of modifiable lifestyle factors on survival from colorectal cancer
Creators: name: Haydon., Andrew
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
title: Eine mehrmalige Anwendung der photodynamischen Diagnostik beim gleichen Patienten kann bedenkenlos ohne Auslösung allergischer Reaktionen angewendet werden – Ergebnisse einer großen monozentrischen Studie
Creators: name: Apfelbeck, M.
name: Grimm, T.
name: Buchner, A.
name: Schneevoigt, B.-S.
name: Kretschmer, A.
name: Grabbert, M.
name: Jokisch, F.
name: Schulz, G.
name: Karl, A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Ziel: Das Ziel dieser Studie war die Evaluation möglicher Nebenwirkungen bei mehrmaliger Verwendung von PDD beim gleichen Patienten im Rahmen der Nachsorge von UCC mittels Zystoskopie oder TUR-B. Material und Methoden: Es wurden Daten von Patienten mit Urothelkarzinom im Zeitrahmen von 2008 [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie
Technology for the next gravitational wave detectors
Creators: name: Mitrofanov, Valery P.
name: Chao, Shiuh
name: Pan, Huang-Wei
name: Kuo, Ling-Chi
name: Cole, Garrett
name: Degallaix, Jerome
name: Willke, Benno
Publisher: name: arXiv
Year: 2016
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: This paper reviews some of the key enabling technologies for advanced and future laser interferometer gravitational wave detectors, which must combine test masses with the lowest possible optical and acoustic losses, with high stability lasers and various techniques for suppressing noise. Sect. 1 of this paper presents a review of the acoustic properties of test masses. Sect. 2 reviews the technology of the amorphous dielectric coatings which are currently universally used for the mirrors in advanced laser interferometers, but for which lower acoustic loss would be very advantageous. In sect. 3 a new generation of crystalline optical coatings that offer a substantial reduction in thermal noise is reviewed. The optical properties of test masses are reviewed in sect. 4, with special focus on the properties of silicon, an important candidate material for future detectors. Sect. 5 of this paper presents the very low noise, high stability laser technology that underpins all advanced and next generation laser interferometers.
title: Impact of preoperative thrombocytopenia on haemorrhagic risk and blood transfusion in patients undergoing radical cystectomy due to urothelial carcinoma
Creators: name: Grimm, T.
name: Buchner, A.
name: Schneevoigt, B.-S.
name: Apfelbeck, M.
name: Grabbert, M.T.
name: Jokisch, F.
name: Kretschmer, A.
name: Schulz, G.
name: Stief, C.G.
name: Karl, A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Introduction and objectives: As recently shown perioperative blood transfusion is associated with impaired oncologic outcome in patients undergoing radical cystectomy (RC) for urothelial carcinoma (UC). In this study we analyzed the impact of preoperative thrombocytopenia (TP) on haemorrhagic risk and[for full text, please go to the a.m. URL]
description: 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie
Search models and the judgement of temporal order
Creators: name: Haworth., Narelle
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.