cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Lalage leucopyga subsp. albiloris Mayr and Ripley
Creators: name: LeCROY, M. A. R. Y.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Campephagidae
Lalage
Lalage leucopyga
Lalage leucopyga albiloris mayr and ripley

description: Lalage leucopyga albiloris Mayr and Ripley
 Lalage leucopyga albiloris Mayr and Ripley, 1941a: 16 (Efate I., New Hebrides).
 Now Lalage leucopyga albiloris Mayr and Ripley, 1941. See Bregulla, 1992: 220.
HOLOTYPE: AMNH 212817, [adult male], collected on Efate Island, Vanuatu, on 2 July 1926, by Rollo H. Beck on the Whitney South Sea Expedition (no. 21294).
COMMENTS: The AMNH number of the type was cited in the original description. Forty­nine paratypes from 11 islands in Vanuatu are AMNH 212807–212811, 212813–212816, 212818–212831, 213747–213749, 213751–213761, 214214–214217, 216088–216092, 217965, 217966, and 221770.
 On 2 July 1926, the Whitney Expedition schooner France was anchored in Undine Bay, ca. 17°30′S, 168°20′E, Efate Island (Beck, unpublished journal, vol. D, Archives, Dept. of Ornithology, AMNH).
description: Published as part of LeCROY, M. A. R. Y., 2003, TYPE SPECIMENS OF BIRDS IN THE AMERICAN MUSEUM OF NATURAL HISTORY. PART 5. PASSERIFORMES: ALAUDIDAE, HIRUNDINIDAE, MOTACILLIDAE, CAMPEPHAGIDAE, PYCNONOTIDAE, IRENIDAE, LANIIDAE, VANGIDAE, BOMBYCILLIDAE, DULIDAE, CINCLIDAE, TROGLODYTIDAE, AND MIMIDAE, pp. 1-156 in Bulletin of the American Museum of Natural History 278 (278) on page 76, DOI: 10.1206/0003-0090(2003)278<0001:tsobit>2.0.co;2, http://zenodo.org/record/13256611
Supplementary document for Tunable Color Generation in CdTe-doped Silicate Glass Enabled by Ultrashort Laser Pulses: Interior Coloring and Multilevel Encryption - 5911491.pdf
Creators: name: Shen, Danyang
name: Qian, Jing
name: Wang, Guande
name: Jiao, Yu-Jie
name: jiao, Yan
name: Zhao, Quan-Zhong
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Campephaga rothschildi , Neumann 1907
Creators: name: LeCROY, M. A. R. Y.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Campephagidae
Campephaga
Campephaga rothschildi

description: Campephaga rothschildi Neumann
 Campephaga rothschildi Neumann, 1907b: 594 (Gmezo im Borana Land).
 Now Campephaga phoenicea (Latham, 1790). See Peters et al., 1960: 205, and Keith et al., 1992: 264.
HOLOTYPE: AMNH 562996, adult male, collected at Gmezo, Borana tribal area, Ethopia, on 24 May 1905, by Baron Maurice de Rothschild. From the Rothschild Collection.
 COMMENTS: The description was based on this single, formerly mounted specimen. Hartert (1922b: 375) noted that it is a specimen of the yellow­shouldered morph of C. phoenicea.
Borana is shown by Neumann (1902, map) as an area just to the east of Lake Stefanie (ca. 04°40′N, 36°50′E [Seltzer, 1962: 1824]) and south of the Sagan River. Baron Maurice de Rothschild (1922) published the results of his trip and also showed Borana (map on p. 1017).
description: Published as part of LeCROY, M. A. R. Y., 2003, TYPE SPECIMENS OF BIRDS IN THE AMERICAN MUSEUM OF NATURAL HISTORY. PART 5. PASSERIFORMES: ALAUDIDAE, HIRUNDINIDAE, MOTACILLIDAE, CAMPEPHAGIDAE, PYCNONOTIDAE, IRENIDAE, LANIIDAE, VANGIDAE, BOMBYCILLIDAE, DULIDAE, CINCLIDAE, TROGLODYTIDAE, AND MIMIDAE, pp. 1-156 in Bulletin of the American Museum of Natural History 278 (278) on page 76, DOI: 10.1206/0003-0090(2003)278<0001:tsobit>2.0.co;2, http://zenodo.org/record/13256611
Conversione elettroni-positroni
Creators: name: AA. VV.
Publisher: name: INFN Open Access Repository
Year: 1971
Subjects: ADONE
Funzionamento a elettroni
Funzionamento a positroni
ALI

description: Passaggio da funzionamento a elettroni a funzionamento a positroni: Pannello Auxiliary [intlus]; Pannello Reli e controlli.
Pericrocotus sordidus Swinhoe
Creators: name: LeCROY, M. A. R. Y.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Campephagidae
Pericrocotus
Pericrocotus sordidus

description: Pericrocotus sordidus Swinhoe
 Pericrocotus sordidus Swinhoe, 1863: 284 (Amoy).
 Now Pericrocotus cantonensis Swinhoe, 1861. See Sibley and Monroe, 1990: 484, Dickinson and Dekker, 2002a: 16, and Dickinson et al., 2002a: 41, 50.
HOLOTYPE: AMNH 563767, immature male, collected at Xiamen (= Amoy), 24°26′N, 118°04′E (Times Atlas), China, on 29 September 1859, by Robert Swinhoe. From the Swinhoe Collection via the Rothschild Collection.
 COMMENTS: Swinhoe (1863: 284) stated that he had a single male specimen from Amoy, ‘‘not quite mature’’, collected on the above date. In bill size and shape, this holotype matches P. cantonensis. This specimen had not previously been recognized as a type.
 Peters et al. (1960: 207) considered cantonensis to be a subspecies of P. roseus.
description: Published as part of LeCROY, M. A. R. Y., 2003, TYPE SPECIMENS OF BIRDS IN THE AMERICAN MUSEUM OF NATURAL HISTORY. PART 5. PASSERIFORMES: ALAUDIDAE, HIRUNDINIDAE, MOTACILLIDAE, CAMPEPHAGIDAE, PYCNONOTIDAE, IRENIDAE, LANIIDAE, VANGIDAE, BOMBYCILLIDAE, DULIDAE, CINCLIDAE, TROGLODYTIDAE, AND MIMIDAE, pp. 1-156 in Bulletin of the American Museum of Natural History 278 (278) on page 76, DOI: 10.1206/0003-0090(2003)278<0001:tsobit>2.0.co;2, http://zenodo.org/record/13256611
Silicon revised format.docx
Creators: name: Muneer, Sowbiya
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 300103
subject: Agricultural molecular engineering of nucleic acids and proteins

description: Silicon (Si), the second most prevalent element in the earth, is not soluble enough for plants to absorb, despite being one of numerous helpful elements. Supplementing with silicon (Si) is seen to be one of the most promising ways to mitigate abiotic stressors like salt and drought. Legume crops are still underutilised, especially mungbean, an important crop in India, despite several research on the effects of salt and silicon stress on various crops. In order to study the impact of exogenous application of Si concentrations on the growth and physiochemical, photosynthesis, and antioxidative pathways of four mung bean cultivars—K1, CO6, CO7, and CO8 exposed to two levels of salinity] [10mMNacl (S3), 20mM NaCl (S5)]—a Pot experiment and field data were collected over the course of two growth seasons (2022–2023). Growth factors like biomass, plant length, height, and photosynthetic measurements were all lowered by salinity stress; however, these effects were lessened by silicon supplementation at a concentration of 5 mM sodium silicate. Under salt stress, the presence of silicon boosted the production of photosynthetic proteins such Photosystem I, Photosystem II, and light harvesting complexes. In the mung bean, salinity stress also resulted in oxidative damage in the form of superoxide radical (O2−) and hydrogen peroxide (H2O2), which raised MDA (lipid peroxidation) and electrolyte leakage. On the other hand, 5 mM sodium silicate has the ability to scavenge free radicals, which lowers electrolyte loss and lipid peroxidation (MDA). Significant silica deposition in the leaf epidermis was associated with this, and in the end, this served as a mechanical barrier to lessen the harmful effects of salt stress. Our simulated investigations, which employed Si as a supplement, indicated that, of all the types used in this study, K1 and CO7 shown resilience to salt stress, but CO6 and CO8 demonstrated sensitivity. Experiments conducted at the field level on yield and growth provided evidence for the study's findings that Si has a negative impact on salt stress. Si reduced the detrimental effects of salt stress overall and supplied a basis for fertigation fertilizer.
Supplementary document for Slow optical vortices in multicoil fiber resonators - 5911567.pdf
Creators: name: Alexeyev, C.
name: Aliyeva, Selime
name: Barshak, Elena
name: Lapin, Boris
name: Yavorsky, Maxim
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: It is the Supplement 1
Yaş Dostu Mekanlar ve Hizmetler
Creators: name: Arun, Özgür
name: Ersözlü, Mert
Publisher: name: Zenodo
Year: 2024

description: Küresel düzeyde demografik bir dönüşüm yaşanıyor. Gelecek on yıl içinde yaşlıların nüfusunun dünya genelinde 1 milyar olması bekleniyor. Türkiye'de demografik dönüşümü hızlı yaşayan toplumlardan birisi. Türkiye’yi günümüzde “hala genç bir toplum!” ya da “yaşlanan bir toplum!” diye tanımlamak yersiz. Bu alarmist söylemler çeyrek yüz yıl öncesine ait. Türkiye bugün çok yaşlı bir toplum. Bu durumu bir risk ya da sorun olarak tanımlamak da yaş ayrımcılığının göstergesi. Toplumsal yaşlanma risk değil, yaşlananlar ve yaşlılar da kategorik olarak sorunlu insanlar değiller.Türkiye’nin ana sorunu yoksullaşarak hızla yaşlanmış olması (Arun, 2022). Kentte ve kırda yoksulluğun değişen, derinleşen biçimleriyle yaşlanan nüfusun ve yaşlıların toplumsal yapı içinde sorunlarla karşılaştığını gözlemliyoruz. 2017 yılında yayın hayatına başlayan Senex: Yaşlılık Çalışmaları Dergisi 2024 yılının ilk sayısında yaş dostu mekân ve hizmetlere yönelik saha araştırmalarından oluşan bilimsel çalışmalara yer veriyor.
Pericrocotus peregrinus subsp. dharmakumari Koelz
Creators: name: LeCROY, M. A. R. Y.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Campephagidae
Pericrocotus
Pericrocotus peregrinus
Pericrocotus peregrinus dharmakumari koelz

description: Pericrocotus peregrinus dharmakumari Koelz
 Pericrocotus peregrinus dharmakumari Koelz, 1950: 6 (Jamwala, Junagarh (sic), Kathiawar Peninsula, India).
 Now Pericrocotus cinnamomeus cinnamomeus (Linnaeus, 1766). See Dickinson and Dekker, 2002a: 16–18, and Dickinson et al., 2002a: 42.
HOLOTYPE: AMNH 803067, adult male, collected at Jamwala, 20°57′N, 70°44′E (J. Hinshaw, personal commun.), Saurashtra, Kathiawar Peninsula, Gujarat, India, on 9 February 1949, by Walter Koelz.
COMMENTS: Although said to be deposited in AMNH, the types described by Koelz (1950) were, in fact, deposited by Koelz in FMNH. To avoid confusion, they were later returned to AMNH, but this holotype still bears FMNH 246496. The eight paratypes for which Koelz gave measurements are in FMNH.
 For information on the use of P. cinnamomeus (Linnaeus, 1766) rather than P. peregrinus (Linnaeus, 1766), see Peters et al. (1960: 209).
Junagarh is a misprint for Junagadh, a former princely state of India, merged in 1949 with Saurashtra (Seltzer, 1962: 889).
description: Published as part of LeCROY, M. A. R. Y., 2003, TYPE SPECIMENS OF BIRDS IN THE AMERICAN MUSEUM OF NATURAL HISTORY. PART 5. PASSERIFORMES: ALAUDIDAE, HIRUNDINIDAE, MOTACILLIDAE, CAMPEPHAGIDAE, PYCNONOTIDAE, IRENIDAE, LANIIDAE, VANGIDAE, BOMBYCILLIDAE, DULIDAE, CINCLIDAE, TROGLODYTIDAE, AND MIMIDAE, pp. 1-156 in Bulletin of the American Museum of Natural History 278 (278) on page 76, DOI: 10.1206/0003-0090(2003)278<0001:tsobit>2.0.co;2, http://zenodo.org/record/13256611
Natural and engineered endolysins to kill pneumococcus and other streptococci
Creators: name: Garcia, Pedro
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: The emergence and spread of antibiotic-resistant bacteria fosters the need for alternative treatments. In this context, phage therapy is already a reality to successfully fight multiresistant bacteria. Among different phage gene products, peptidoglycan hydrolases belong to the tightly controlled late genes that provoke the lysis of bacterial cells for progeny release. These enzymes, also called endolysins, are weapons that target specific peptidoglycan bonds leading to lysis of susceptible bacteria when added from the outside. We have used the pneumococcal phage-encoded Pal amidase and Cpl-1/Cpl-7 lysozymes to kill susceptible streptococcal strains. In addition, the bactericidal effect of Cpl-7 has been improved by changing the net charge of the protein, and different chimeric enzymes by fusing catalytic and cell wall binding domains from parental proteins have been constructed. Specifically, 5 µg/ml of the chimeric Cpl-711 lysozyme was capable of killing about 7 logs of pneumococcal R6 strain. Cpl-711 also decreased biofilm formation and reduced 4 logs of the bacterial population at 1 µg/ml. Overall, this enzyme is the most powerful endolysin against pneumococci, including multiresistant isolates. All these results were validated in animal models of infection, suggesting that these specialized endolysins offer a promising therapeutic perspective against bacterial infections.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Gingival Bleeding Tendency in Liver Transplant Recipients Administered  Immunosuppressive Drugs
Creators: name: Aly, Lobna
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Objective: The study purpose was to assess the amount of VEGF and PDGF-B gene expression in gingival connective tissues and its correlation to increased gingival bleeding tendency in liver transplant patients receiving CsA or Tacrolimus.

Methodology: Ten Liver transplant recipients were included and medicated with TAC (Group I), and with CsA (Group II). Five subjects served as healthy controls (Group III). Gingival samples were obtained and tissue sections were stained with HE. Another section was examined by immunohistochemical   staining using VEGF and PDGF-B antibodies.

Results: Histopathological examination of gingival sections in gp II showed marked hyperplasia of lining mucosa, elongated gingival papillae, and Lamina propria showed marked mononuclear cellular infiltration. Meanwhile gp I showed mild gingival thickening and no vascular proliferation were observed. VEGF and PDGF-B immunostaining results showed least immunoreactivity in Gp III. Moderate expression was observed in  Gp I. Currently strong expression of both was observed in Gp II.

Conclusion: This study demonstrates a decrease expression of VEGF and PDGF-B in TAC group, which is associated with absence of gingival bleeding tendency when compared to CsA and thus it may have potential as an alternative immunosuppressant for individuals susceptible to spontaneous gingival bleeding tendency with CsA therapy.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Supplementary document for Slow optical vortices in multicoil fiber resonators - 5911567.pdf
Creators: name: Alexeyev, C.
name: Aliyeva, Selime
name: Barshak, Elena
name: Lapin, Boris
name: Yavorsky, Maxim
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: It is the Supplement 1
BACTERIOPHAGE: AN ALTERNATIVE TO ANTIBIOTICS TO FIGHT MASTITS IN CATTLE
Creators: name: Bhatt, Vaibhav D.
name: Joshi, Bhumika R.
name: Kunjadia, Anju P.
name: Joshi, Chaitnya G.
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: In the present study, bacteriophages were used against multi drug resistant bacteria isolated from the milk of cattle suffering from Mastitis, as an alternative treatment to antibiotics. Infected milk samples were collected from indigenous and crossbred cattle and subjected for bacterial isolation. Fourteen different bacterial isolates were identified and DNA was extracted. Genes (Tet-K, Msr-A and Mec-A) providing antibiotic resistance to the bacteria were screened by Polymerase Chain Reaction and results were validated with traditional antibiotic assay. Total 3 bacteriophages were isolated from sewage samples, collected from sewage treatment plant, Rajkot, Gujarat. The efficacy of phages were checked against multi drug resistant bacteria, identified by PCR. In-vivo study was carried out for phage therapy in mammary glands of female Wister rats. Mammary glands were infused with MDR isolates for 3 consecutive days. Recovery was observed in infected rats after intramammary infusion of sterile phage suspension. From day 4th onwards, level of C-reactive protein was significantly increases upto day 12th however, significant reduction was observed between days 12th to 18th post treatment. Bacteriophages have significant potential as antibacterial agents and their ability to replicate exponentially within their hosts and their specificity, make them ideal candidates for more sustainable mastitis control.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
ISOLATION AND CHARACTERIZATION OF WATERBORNE, LYTIC BACTERIOPHAGE WITH POTENTIAL FOR BIOCONTROL OF MULTIDRUG RESISTANT KLEBSIELLA PNEUMONIAE
Creators: name: Ahiwale, Sangeeta Sanjay
name: Kapadnis, Balasaheb Pandurang
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Multidrug resistant strains of Klebsiella pneumonniae are ever emerging and creating a big challenge to healthcare worldwide. Therefore, there is a growing interest for potent lytic bacteriophages against multidrug resistant Klebsiella pneumonniae. This study reports isolation and characterization of a potent, waterborne lytic phage of multidrug resistant Klebsiella pneumonniae that was isolated from the hospital environment. Phage specific to Klebsiella pneumoniae (KPP) was isolated from river water by double agar layer plaque assay technique and characterized based on the criteria that are recommended by Ackermann (2009).Phage was identified as a member of the family Myoviridae, which is morphologically similar to the FC3 phage group.  It is stable within a wide range of pH (5 to 10) and temperatures (4 to 50 oC) (Fig.1a &b). The burst size was 120 phage particles per infected cell after 45 min at 37 oC(Fig.2) The phage DNA size was 54 kb and a proteome of 9 bands in the gradient gel. KPP is found to be stable over a wide range of pH (5 to 9) and temperature (4 to 50 C˚) indicating their wide applications to control Klebsiella. pneumoniae infections.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Collagen sandwich culture affects intracellular polyamine levels of human hepatocytes
Creators: name: Weiss, Thomas S.
name: Jahn, B.
name: Cetto, M.
name: Jauch, K. W.
name: Thasler, W. E.
Publisher: name: Universität Regensburg
Year: 2002
Subjects: subject: 610 Medizin

description: Abstract
Extracellular matrices, like collagen layers, play an important role in preventing dedifferentiation of hepatocytes in long-term culture experiments. It has also been shown that polyamines are crucial for cell growth and liver differentiation – regeneration. Primary cultured hepatocytes with their low mitotic activity might be a valuable tool in studying the role of polyamines in differentiation. Here, our goal was to investigate whether an extracellular cell culture matrix can influence intracellular polyamine levels in human hepatocytes during long-term culture. Primary human hepatocytes were isolated from surgical tissue resections and were maintained either in single collagen (SG) or double collagen gel (DG) layer (sandwich) culture systems. Cell viability and function were examined and intracellular polyamine levels were measured using a highly sensitive high performance liquid chromatography (HPLC) method. Hepatocytes showed high viability in both culture systems used, but albumin secretion was diminished in SG cultured hepatocytes after 14 days. In general, total intracellular polyamine levels of hepatocytes decreased markedly in both SG and DG within the first days of culture, but remained constant until day 21 with a SG/DG ratio of about 1.4. Individual polyamines levels were dependent on the culture time and system, where spermine decreased and putrescine increased in both SG and DG over time (day 14), but spermidine increased only in DG. Our results suggest that polyamine levels, in particular putrescine, might be important regulators of hepatocyte specific function in vitro and therefore serve as a marker of differentiation for cultivated human hepatocytes.
Preclinical trials on phage-based suppositories
Creators: name: ALESHKIN, Vladimir Andrianovich
name: Kiseleva, Irina
name: Bochkareva, Svetlana
name: Borisova, Olga
name: Rubalsky, Evgeny
name: Anurova, Mariya
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: A formulation has been designed and a pilot technology tested for producing suppositories based on a three-phage cocktail with each strain at a titer of at least 108 pfu/suppository. The concentration of phage particles in feces, urine and blood of the rabbits reached its peak (104-106 pfu/ml) 4.5-6 hours after a single rectal administration of suppositories. All of the bacteriophage strains were defined in the rabbits in insignificant quantities 24 hours after the suppositories had been administered. Functional and morphological adequacy of the virulent particles persistent in the animals was confirmed by both the possibility to define the specific activity of bacteriophages isolated from clinical material by the Gratia method and the presence in the serum of IgG-antibodies for bacteriophage capsid on the 23rd day after a single administration of suppositories in the rabbits. Pharmacokinetic curves of phage titers in feces, urine and blood (Figure) were completely identical in shape, which testified, along with the formation of antibodies specific to protein structures of viral particles, for systemic pattern of performance of bacteriophages, infiltrating after the per rectum administration into the bloodstream, liver, gallbladder, kidneys, bladder, small and large intestine of lab animals.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Supplementary document for Plasmonic fiber-optic sensing system for in situ monitoring the capacitance and temperature of supercapacitors - 5911709.pdf
Creators: name: Qian, Siyu
name: Chen, Xinlong
name: Jiang, Shiyu
name: Sun, Qiang
name: Chen, Xuefeng
name: Lu, Jinxin
name: Geng, Yikai
name: Duan, Musen
name: Li, Xiaoyou
name: liu, shengchun
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary test data and pictures
Our Practice Newsletter : By Pharmacists For Pharmacists. Issue 3
Creators: name: Khurana, Rosanne
name: Thorne-Humphrey, Lucas
name: Reardon, Jillian
Publisher: name: The University of British Columbia
Year: 2020

description: In the feature article this issue of Our Practice, we dive into the flow of a typical pharmacist consultation, from establishing patient priorities, gathering information, identifying and prioritizing drug therapy problems (DTPs), scheduling follow-up appointments, and finally, communicating with other healthcare providers such as physicians and nurse practitioners the patient’s circle of care. The case study this issue explores the efficacy and safety profile of SGLT2 inhibitors in the treatment of diabetes.
Bacteriophage therapy for the control of vibriosis in greenlip abalone (Haliotis laevigata)
Creators: name: Wang, Yanhui
name: Barton, Mary
name: Elliott, Lisa
name: Li, Xiaoxu
name: Abraham, Sam
name: O'Dea, Mark
name: Munro, James L
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Bacteriophage therapy has demonstrated promising results towards the control of bacterial infections within the aquaculture industry. This current research describes the efficacy of bacteriophage therapy in controlling vibriosis within abalone (Haliotis laevigata). Bacteriophages were isolated and used in in vitro assays to determine the effect of each specific phage on the growth of specific Vibrio harveyi isolates. To demonstrate efficacy, an in vivo bioassay was performed using abalone (H. laevigata) at a temperature of 24 °C. Characterisation of the phages revealed they were from the family, Siphoviridae. The phages had different antimicrobial abilities towards different Vibrio harveyi isolates in the in vitro assays and the bioassay demonstrated improved survival of abalone treated with phage. The results of the bioassay showed that the negative control and phage control were statistically identical, with 100% survival, but they were different from the positive bacterial control, with a 0% survival. The bacteria + phage treated group showed increased accumulative survival of 70%. This is the first study to demonstrate the efficacy of bacteriophage therapy treatment for abalone and demonstrates that if abalones are treated with bacteriophage shortly after Vibrio harveyi infection, the accumulative survival could be significantly increased.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
BACTERIOPHAGES DERIVED NATURAL RESISTANCE TO BOVINE MASTITIS REVEALED BY PYROSEQUENCING APPROACH
Creators: name: Bhatt, Vaibhav D.
name: Kher, Mukesh N.
name: Kunjadia, Anju P.
name: Joshi, Chaitnya G.
name: Sheth, Navin R.
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Metagenomic analysis of milk samples collected from local cattle breed, kankrej (Bos indicus), Gir (Bos indicus) and Crossbred (Bos indicus X Bos taurus) cattle harbouring subclinical mastitis was carried out by next-generation sequencing 454 GS-FLX technology. Around 56 different species including members of Enterobacteriales, Pseudomonadales, Bacillales and Lactobacillales with varying abundance were detected in infected milk. Interestingly presence of bacteriophages against Staphylococcus aureus, Escherichia coli, Enterobacter and Yersinia species were observed, especially Enterobacteria and E. coli phages (0∙32%) in Kankrej, Enterobacteria and Staphylococcus phages (1∙05%) in Gir and Staphylococcus phages (2∙32%) in crossbred cattle. Metabolic profiling also revealed the presence of genes associated with phages, prophages, transposable elements and plasmids as 1∙80, 2∙49 and 4∙29% in Kankrej, Gir and Crossbred cattle, respectively. This is probably the first report describing the presence of bacteriophages along with their hosts in the infected mammary gland. Our findings suggest that phages may be involved in imparting natural resistance of the cattle against pathogens. The power of 454 pyrosequencing showed detailed pattern of distribution of bacteria and bacteriophages in the mastitic milk.
 Key words: Metagenomic analysis, mastitis, 454 GSFLX technology
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Pericrocotus yvettae Bangs
Creators: name: LeCROY, M. A. R. Y.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Campephagidae
Pericrocotus
Pericrocotus yvettae

description: Pericrocotus yvettae Bangs
 Pericrocotus yvettae Bangs, 1921: 583 (Malipa, Burma border, 3000 feet altitude).
 Now Pericrocotus ethologus yvettae Bangs, 1921. See Dickinson and Dekker, 2002a: 18–20, and Dickinson et al., 2002a: 43.
HOLOTYPE: AMNH 143365, adult male, collected at Ma­li­pa, 3000 ft, 23°42′N, 98°45′E (Times Atlas), Myanmar (on the Yunnan border), on 10 March 1917, by Roy Chapman Andrews and Edmund Heller (no. 561). From the Asiatic Zoological Expedition, 1916–1917.
 COMMENTS: A second specimen, AMNH 143367, the only female collected by the expedition, was doubtfully referred to this taxon by Bangs (1921: 584), but he incorrectly cited the locality as Ma­li­pa; it was, in fact, from Tai­pingpu, Yunnan, China, and has been reidentified as P. brevirostris.
description: Published as part of LeCROY, M. A. R. Y., 2003, TYPE SPECIMENS OF BIRDS IN THE AMERICAN MUSEUM OF NATURAL HISTORY. PART 5. PASSERIFORMES: ALAUDIDAE, HIRUNDINIDAE, MOTACILLIDAE, CAMPEPHAGIDAE, PYCNONOTIDAE, IRENIDAE, LANIIDAE, VANGIDAE, BOMBYCILLIDAE, DULIDAE, CINCLIDAE, TROGLODYTIDAE, AND MIMIDAE, pp. 1-156 in Bulletin of the American Museum of Natural History 278 (278) on page 77, DOI: 10.1206/0003-0090(2003)278<0001:tsobit>2.0.co;2, http://zenodo.org/record/13256611
The challenges of phage therapy in dentistry
Creators: name: Beyth, Nurit
name: Glaser, Shunit
name: Haddad, Yael Houri
name: Wilensky, Asaf
name: Hazan, Ronen
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Despite the significant advances in dentistry dental diseases including periodontitis, caries and root canal infections are still highly prevalent in humans. These diseases cause misery and economic burden worldwide. Since dental diseases are associated with biofilm derived bacterial infections obstinate to antibiotic treatment, they are an attractive target for phage therapy. However, the approach of phage therapy is challenged by the fact that oral microbiome contains ~1000 bacterial species, of which many are uncultivable or difficult to grow anaerobes.To date we have isolated and characterized a number of phages against the root canal pathogen Enterococcus faecalis and have shown that these phages virtually eliminate planktonic and biofilm cultures. We have shown also a proof of concept in ex-vivo model of human teeth and currently we are in the midst of in vivo experiments in a rat model [1,2]. In addition, we are in the process of isolating novel phages against other dental bacteria in order to create a large phage collection of anti-oral bacteria.  We believe that despite the difficulties, by targeting the right key organisms, phage therapy and phage prophylaxis are promising approaches in dentistry that may significantly improve oral health.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Isolation and Characterization of Bacteriophages from Laban Jameed*
Creators: name: Ishnaiwer, Murad Mohammad
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Laban jameed is a dried salty dairy product obtained by fermentation of milk using a complex population of lactic acid bacteria. Two phages were isolated: one from sheep milk jameed (PPUDV) and the other from cow milk jameed (PPURV). The PPUDV phage was identified as a ssDNA virus with 20 kb genome, whereas PPURV phage possessed a dsRNA genome of approximately 20 kb. The phage bacterial strain hosts were identified as Lacto-bacillus helveticus and Bacillus amyloliquefaciens for PPUDV and PPURV, respectively. One step growth curve using a double layer plaque assay test was carried out to monitor the phage life cycle after host infection. PPUDV showed a latent period of about 36 h, burst period of 70 h and a burst size of about 600 Plaque Forming Units (PFU) per infected cell. PPURV phage showed a latent period of about 24 h, burst period of 47 h and a burst size of about 700 PFU per infected cell. SDS-PAGE analysis of total viral proteins showed at least three major bands (27, 40, and 45 kDa) for PPUDV. This study adds new insights into the complexity of dairy contamination and fermentation microbiology
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Effect of the mixture of Dong Quai, Tang Shan, Linchi and citronellol on the infection and ulcer of Helicobacter pylori
Creators: name: Wang, Chin-Kun
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: The reasons for gastrointestinal ulcer were very complex, including non-steroidal anti-inflammation drugs, gastrinoma and infection of Helicobacter pylori. H. pylori is thought to be the major cause. H. pylori was found in 80% of gastrointestinal patients.10%~15% of H. pylori carriers could induce ulcer diseases, 2~5% of them would lead to gastric carcinoma. Therapy for ulcer only but not completely destroying H. pylori could induce the second ulcer in one year. To prevent the infection of H. pylori had become the major treatment of gastrointestinal ulcer. The ethanol extract of the mixture of Dong Quai, Tang Shan, Linchi and citronellol significantly inhibit the infection and ulcer of H. pylori. This effect was not to destroy the bacteria, but greatly suppress the adhesion of H. pylori and reduce Cag A secretion and the series of inflammation. In addition, this mixture could effectively promote the healing of ulcers. The phenolics of the mixture play important roles and citronellol, ferulic acid and quercetin were critically important. This improved that this mixture had great potential in the future.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Isolation of Lytic Bacteriophages against Multidrug-Resistant Enterococcus faecalis ST55 Isolated from Research Macaques
Creators: name: Lieberman, Mia T
name: Citorik, Robert J
name: Lu, Tim K
name: Fox, James G
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Objectives:  Multidrug-resistant Enterococcus faecalis (MDR-Ef) is a major cause of human nosocomial infections1. We have identified MDR-Ef of sequence type (ST) 55 from multiple cephalic recording chambers of macaques used in neuroscience research. Whole genome sequencing identified genes encoding resistance to aminoglycosides, tetracycline, erythromycin, and macrolide antibiotics. Our aim was to isolate lytic bacteriophages with activity against MDR-Ef.

 Methodology: Sterile-filtered sewage samples were combined with double-strength phage broth and inoculated with one of seven ST55 isolates. Following overnight incubation, enriched samples were centrifuged and supernatants spot tested on ST55 isolates using a modified double-agar overlay method2. Individual plaques were purified and serially passaged three times prior to overnight polyethylene glycol precipitation, uranyl actetate staining and transmission electron microscopy (TEM).

 Results: Three isolates showed the strongest lytic activity against all seven ST55 isolates based on plaque size. Initial TEM imaging identified the three phages as likely Siphoviruses of two distinct morphologies, featuring long, flexible, apparently noncontractile tails. Capsid morphologies included icosahedral (~65nm diameter) and two sizes of prolate capsids (~99nm x 36nm and ~109nm x 44nm).
Conclusions: Lytic  phage therapy offers a valuable alternative to traditional antimicrobials  against highly drug-resistant bacteria. Future work includes phage  sequencing and characterization of anti-biofilm activity.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Hemipus picatus subsp. insulae Koelz
Creators: name: LeCROY, M. A. R. Y.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Tephrodornithidae
Hemipus
Hemipus picatus
Hemipus picatus insulae koelz

description: Hemipus picatus insulae Koelz
 Hemipus picatus insulae Koelz, 1939: 69 (Wavenden, Ceylon).
 Now Hemipus picatus leggei Whistler, 1939. See Peters et al., 1960: 218, and Dickinson et al., 2002a: 45.
HOLOTYPE: AMNH 655585, unsexed, collected at Wavendon, 3500 ft, 07°04′N, 80°41′E (Gazetteer 49, USBGN), Sri Lanka, on 8 February 1881, by Henry J. Elwes. From the Rothschild Collection.
COMMENTS: The AMNH number of the type was cited in the original description. The holotype, unsexed on the original label, has been sexed as a male on the Rothschild label. The six paratypes mentioned by Koelz (1939: 69) are AMNH 655581–655584, 655586, and 655612.
 Hemipus p. insulae, published 5 June 1939, is a junior synonym of H. p. leggei, published 15 May 1939 (Peters et al., 1960: 218).
description: Published as part of LeCROY, M. A. R. Y., 2003, TYPE SPECIMENS OF BIRDS IN THE AMERICAN MUSEUM OF NATURAL HISTORY. PART 5. PASSERIFORMES: ALAUDIDAE, HIRUNDINIDAE, MOTACILLIDAE, CAMPEPHAGIDAE, PYCNONOTIDAE, IRENIDAE, LANIIDAE, VANGIDAE, BOMBYCILLIDAE, DULIDAE, CINCLIDAE, TROGLODYTIDAE, AND MIMIDAE, pp. 1-156 in Bulletin of the American Museum of Natural History 278 (278) on page 78, DOI: 10.1206/0003-0090(2003)278<0001:tsobit>2.0.co;2, http://zenodo.org/record/13256611
Phage-fused epitope immunogens from Leishmania infantum confer cross-protection against Leishmania amazonensis infection
Creators: name: Costa, Lourena Emanuele
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Two mimotopes of Leishmania infantum identified by phage display were evaluated as vaccine in BALB/c mice against Leishmania amazonensis. The epitope-based immunogens, B10 and C01; were used without association of a Th1 adjuvant, and  clones were administered isolated or in combination into animals. Both clones showed a specific production of IFN-g, IL-12, and GM-CSF after in vitro spleen cells stimuli and were able to induce protection. Significant reductions of parasite load of infected footpads, liver, spleen, bone marrow, and paws’ draining lymph nodes were observed in the immunized mice, in comparison to the control groups. Protection was associated with an IL-12-dependent production of IFN-g, mediated mainly by CD8+ T cells, against parasite proteins. Protected animals also presented low levels of IL-4 and IL-10, as well as increased levels of parasite-specific IgG2a antibodies. The association of both antigens resulted in an improved protection in relation to their individual use. Besides, the absence of adjuvant did not diminish the cross-protective efficacy against infection.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Microbiota and virome changes after fecal transplantation for Clostridium difficile infection in a “Zurich patient”
Creators: name: Broecker, Felix
name: Klumpp, Jochen
name: Moelling, Karin
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Fecal transplantation (FT) is a promising therapeutic option for antibiotic-refractory Clostridium difficile infection. FT utilizes donor feces with complex bacterial and viral communities to limit C. difficile and revert inflammation. A central rather unexplored role in FT is played by phages that largely influence bacterial communities in response to environmental changes. They are activated during obesity, inflammation, and promote bacterial lysis and reduction of microbiota complexity as disease indicators. Since phages behave differently in the intestine than under laboratory conditions, more research is needed.  Here, we describe the dynamic microbiota changes of a C. difficile patient cured by FT since five years, the longest follow-up period so far. We reported on the microbiota and the virome by deep sequencing and observed that low phage abundance correlated with recovery and absence of inflammation. Surprisingly, we detected Chlorella virus-related sequences, an algae-specific giant virus, for the first time in the human intestine. Similarities of the gut phage-bacterial interplay and the well-understood marine ecosystems are striking. Based on these findings, we discuss possible implications of intestinal viruses on future microbiota therapies.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Phage therapy is effective in a mouse model of bacterial equine keratitis
Creators: name: Furusawa, Takaaki
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: Bacterial keratitis of the horse is mainly caused by staphylococci, streptococci, and pseudomonas. Of these bacteria, Pseudomonas aeruginosa sometimes causes rapid corneal corruption and, in some cases, blindness. Antimicrobial resistance can make treatment very difficult. Therefore we examined the use of phage to treat horse bacterial keratitis. We isolated Myoviridae or Podoviridae phages, which together have a broad host range. They adsorb efficiently to host bacteria; over 80% of ΦR18 phage were adsorbed to host cells after 30 seconds. In our keratitis mouse model, administration of phage within 3 hours also could kill bacteria and suppress keratitis. A phage MOI of 100 times the host bacteria number could kill host bacteria effectively. A cocktail of two phages suppressed bacteria in the keratitis model mouse. These data demonstrated that phages in this study could completely prevent the keratitis caused by P. aeruginosa in a keratitis mouse model. Furthermore, these results suggest phage may be more effective prophylaxis for horse keratitis than is the current preventive use of antibiotics. Such treatment may reduce use of antibiotics and, therefore, antibiotic resistance. Further studies are required to assess phage therapy as a candidate for treatment of horse keratitis.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Bacteriophage-mediated elimination of Escherichia coli and Pseudomonas aeruginosa for cystic fibrosis applications
Creators: name: Trac, Eric
name: Cira, Nate
name: Bollyky, Paul
name: Cornfield, David
name: Quake, Stephen
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: With antibiotic resistance on the rise, phage therapy is a promising alternative to antibiotics as phages offer high specificity to a range of bacterial hosts and the ability to multiply in, evolve with, and kill their hosts. In cystic fibrosis (CF), bacterial infections of the airways are common and pulmonary disease is the primary cause of morbidity and mortality. Despite aggressive antibiotic therapy, virulent bacteria can become resistant and persist, contributing to patient decline. We investigated the in vitro efficacy of diverse bacteriophages against Escherichia coli as a model organism and transfer our approaches to CF-associated clinical isolates of Pseudomonas aeruginosa. Various doses and cocktails of phages were used to understand phage and bacteria dynamics over time. Using a mass-action kinetic approach, bacterial emergence of resistance to phage therapy was modeled to determine conditions that limit the development of phage resistance. Phages were characterized based on sequence analysis, transmission electron microscopy (TEM), and infectivity profiles across a library of bacterial strains. Understanding the efficacy of phage therapy in vitro will encourage and inform future phage-based treatments for CF and other human conditions plagued by antibiotic resistance.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Characterization of a bacteriophage, isolated from chicken farms, that is lytic against mcr-positive Escherichia coli strains
Creators: name: Pang, Maoda
name: He, Tao
name: Sun, Lichang
name: Wang, Ran
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: The occurrence and prevalence of mcr gene in Gram-negative bacteria from animals was firstly reported in 2015, which greatly threat the values of the human last-resort antimicrobial-colistin. Here we have isolated a lytic bacteriophage, designated vB_EcoM_mcr1, from sewage effluent of a chicken farm in Jiangsu, Mid-east of China, which could infect mcr-positive Escherichia coli strains. Electron microscopy showed Phage vB_EcoM_mcr1 does not resemble to any known family of the phage, with an isometric head (110 nm) and a short contractile tail (35 nm). The phage showed a narrow host ranges against E. coli isolates of chicken origin, lysing 3 of 34 (8.8%) mcr-positive strains. Its latent period and burst size were approximately 5 min and 34 PFU/cell, respectively. The genome of phage vB_KpnM_mcr1 was double stranded DNA and estimated to be about 60 kb. The bacteriolytic activity of this phage at a multiplicity infection (MOI) of ≥0.001 indicted its efficiency for reducing bacterial growth. It is the first time to identify the phage, vB_EcoM_mcr1,which could infect mcr-positive E. coli. These findings suggest that phage vB_EcoM_mcr1 could be considered as a potential therapeutic or prophylactic candidate against mcr-positive E. coli infection in chicken.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Characterization of a lytic Podoviridae bacteriophage against NDM-producing Klebsiella pneumoniae isolated from dairy farms in Mid-east of China
Creators: name: He, Tao
Publisher: name: Journal of Targeting Infectiuos Diseases
Year: 2016

description: The occurrence and prevalence of New Delhi metallo-β-lactamase (NDM) in Gram-negative bacteria from animals not only poses a challenge to the clinical therapy, but also represents the threat for public health. Here we have isolated a lytic bacteriophage, designated vB_KpnM_he1, from sewage effluent of a dairy farm in Jiangsu, Mid-east of China, which could infect several NDM-producing Klebsiella pneumoniae strains, isolated from dairy cows. Electron microscopy showed Phage vB_KpnM_he1 resembles to members of the family Podoviridae. The phage showed relatively broad host ranges against K. pneumoniae isolates of cow origin, including NDM-positive and NDM-negative strains. Its latent period and burst size were approximately 5 min and 32 PFU/cell, respectively. Phage vB_KpnM_he1 was able to survive in a pH range between 4 and 10. However, a treatment of 80℃ for 30 min completely inactivated the phage. The genome of phage vB_KpnM_he1 was double stranded DNA and estimated to be about 40 kb. The bacteriolytic activity of phage vB_KpnM_he1 at a multiplicity infection (MOI) of ≥0.0001 indicted its efficiency for reducing bacterial growth. These findings suggest that phage vB_KpnM_he1could be considered as a potential therapeutic or prophylactic candidate against K. pneumoniae infection in dairy cows.
description: Journal of Targeting Infectiuos Diseases, Vol 1, No 1 (2016)
Supplementary document for Ultrafast nonlinear absorption with multiple transformations (SA-RSA-SA) and transient dynamics of gold nanobipyramids - 5915677.pdf
Creators: name: Chen, Shuang
name: Niu, Rui
name: Gao, Yachen
name: Zhou, Wenfa
name: Liu, Kun
name: Wang, Yuxiao
name: Song, Yinglin
name: Zhang, Xueru
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Experiment setup of open aperture Z-scan measurements and femtosecond time-resolved transient absorption measurement
The Role of Dark Matter in Establishing Fundamental Constants
Creators: name: Stewart, Chris
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Dark matter
subject: fundamental constants
subject: gravitational constant
subject: cosmological constant
subject: atomic clocks
subject: scalar fields
subject: cosmology
subject: quantum field theory
subject: Astrophysics
subject: astrophysics
subject: Physics
subject: Mathematical physics
subject: Physics/methods
subject: Physics/standards
subject: Physics/education
subject: Theoretical physics

description: Abstract:

The nature of dark matter remains one of the greatest mysteries in modern physics. While its gravitational effects on galactic rotation curves, cosmic structure formation, and gravitational lensing are well-documented, its potential influence on fundamental constants of nature has received increasing theoretical attention. This paper explores whether dark matter plays a direct role in setting or influencing fundamental physical constants, such as the gravitational constant (G), the fine-structure constant (α), the proton-to-electron mass ratio (μ), and the cosmological constant (Λ).

We analyze possible couplings between dark matter fields and standard model parameters, investigating whether variations in dark matter density, interaction cross-sections, or scalar field components could lead to observable time-dependent or spatial variations in fundamental constants. Using constraints from atomic clock experiments, quasar absorption spectra, big bang nucleosynthesis (BBN), and large-scale cosmological evolution, we evaluate whether dark matter could serve as an underlying regulator of key physical properties.

Key Highlights:

Theoretical models linking dark matter interactions with fundamental constants.

Constraints from observational cosmology, including BBN and quasar spectral analysis.

Possible deviations in atomic clock measurements under varying dark matter density.

Implications for modified gravity and unification theories.

Potential gravitational wave signatures if fundamental constants evolve due to dark matter interactions.

By merging insights from quantum field theory, cosmology, and precision experimental physics, this paper provides a new perspective on the relationship between dark matter and the fundamental constants that govern physical laws.

Keywords: Dark matter, fundamental constants, fine-structure constant, gravitational constant, cosmological constant, atomic clocks, scalar fields, cosmology, quantum field theory, astrophysics.