cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Intrinsically superparamagnetic Fe-hydroxyapatite nanoparticles positively influence osteoblast-like cell behaviour
Creators: name: Cunha, Carla
name: D’Alessandro, Teresa
name: Sandri, Monica
name: Giavaresi, Gianluca
name: Marcacci, Maurilio
name: Hung, Clark T.
name: Tampieri, Anna
name: Panseri, Silvia
Publisher: name: Columbia University
Year: 2012
Subjects: Hydroxyapatite
Orthopedics
Paramagnetism
Nanobiotechnology
Nanoparticles
Biomedical engineering
Medicine

description: Background: Superparamagnetic nanoparticles (MNPs) have been progressively explored for their potential in biomedical applications and in particular as a contrast agent for diagnostic imaging, for magnetic drug delivery and more recently for tissue engineering applications. Considering the importance of having safe MNPs for such applications, and the essential role of iron in bone remodelling, this study developed and analysed novel biocompatible and bioreabsorbable superparamagnetic nanoparticles, that avoid the use of poorly tolerated magnetite based nanoparticles, for bone tissue engineering applications. Results: MNPs were obtained by doping hydroxyapatite (HA) with Fe ions, by directly substituting Fe2+ and Fe3+ into the HA structure yielding superparamagnetic bioactive phase. In the current study, we have investigated the effects of increasing concentrations (2000 μg/ml; 1000 μg/ml; 500 μg/ml; 200 μg/ml) of FeHA MNPs in vitro using Saos-2 human osteoblast-like cells cultured for 1, 3 and 7 days with and without the exposure to a static magnetic field of 320 mT. Results demonstrated not only a comparable osteoblast viability and morphology, but increased in cell proliferation, when compared to a commercially available Ha nanoparticles, even with the highest dose used. Furthermore, FeHA MNPs exposure to the static magnetic field resulted in a significant increase in cell proliferation throughout the experimental period, and higher osteoblast activity. In vivo preliminary results demonstrated good biocompatibility of FeHA superparamagnetic material four weeks after implantation into a critical size lesion of the rabbit condyle. Conclusions: The results of the current study suggest that these novel FeHA MNPs may be particularly relevant for strategies of bone tissue regeneration and open new perspectives for the application of a static magnetic field in a clinical setting of bone replacement, either for diagnostic imaging or magnetic drug delivery.
ALISHER NAVOIY "LISON UT-TAYR" DOSTONI VA UNGA ISHLANGAN MINIATYURALAR
Creators: name: Arifboyev, Sherzod
Publisher: name: Zenodo
Year: 2025

description: Maqolada, Аlisher Navoiyning “Lison ut-tayr” dostoni, dostonning 960/1553 yilda Buxoroda koʼchirilgan, Parij Milliy kutubxonasida saqlanayotgan (Suppl. Turk 996.) nodir nusxasi va unga ishlangan miniatyuralar, dostondagi - Shayx Sanʼon, shoh va darvesh, xasis, basralik ziqna, Аsmaiy va oshiq haqidagi hikoyatlar syujeti asosida ishlangan miniatyuralar matn bilan qiyosiy tahlil qilingan. Shuningdek, miniatyuralardagi obrazlar - ranglar, tabiat manzaralari v.b. orqali ifodalangan ramziy maʼnolar haqida fikr yuritilgan, baʼzi miniatyuralar haqidagi yanglish fikrlarga aniqlik kiritilgan.
Pulsed Laser Deposition Technique for Controlling Micro-to-Nanoscale Thickness and Deposition Stress in Thin Films for Photonic Waveguide Engineering
Creators: name: Kumi-Barimah, Eric
name: Sarathkumar Loganathan
name: Sharma, Geeta
name: Animesh Jha
Publisher: name: Zenodo
Year: 2022

description: Over the last 25 years has seen an unprecedented increase in the growth of phonic components based on semiconductor lasers, glass and polymer based optical fibres, organic LED, and solid-state lasers. Each of these components suffers from its intrinsic materials related limitations, which then limit the performance in integrated devices. A solution to the materials limitation is to develop device fabrication strategy which then allows multi-materials processing on a substrate, without compromising the structural, thermal, and spectroscopic performances. The challenge then one confronts is that the semiconductors are grown on an MBE machine, whereas the polymeric thin film materials are fabricated by traditional spin coating. By comparison, the glass and crystal based materials are processed via sputtering, or sol-gel techniques. None of these techniques, therefore, are compatible for a single-step device fabrication, due to materials chemical and physical incompatibility. A vast majority of rare-earth ion doped glass- and crystal-based devices are often pumped with semiconductor lasers, which then suggests that the glass-semiconductor devices might perform better when structurally integrated, and that engineering such structures might lead to reduction in pump energy and high photon-to-photon conversion. In this presentation, we explain the nano- and femto-second pulsed laser deposition techniques for controlling the structure of thin-films grown on desired silica-on-Si (SiO2-Si), silica, and silicon substrates. Examples of materials deposition on dissimilar substrates for stress-matched waveguide fabrication are discussed and the light emission properties of rare-earth ion-doped glass, Si, polymer, and 2D-MoS2 films are explained. The thin film stress modelling tool (COMSOL) was used a priori for waveguide engineering for ascertaining the extent to which the structural incompatibility, so that the mismatch strain can be minimized during deposition by controlling thickness. The structure and spectroscopic properties of rare-earth ion doped thin films on silica, polymer, and semiconductor GaAs substrates were examined in detail and are reported. We demonstrate the formation of glass-polymer super lattice structures, ion-implanted waveguide structures, and nano-silicon deposited waveguides for semiconductor integration. The machining properties of such composite structures using femto-second Ti-sapphire lasers is also described, which clearly shows that such complex structures from start-to-finish can be fabricated using different types of pulsed lasers. The amplified spontaneous emission and gain properties of such waveguides are characterized for a range of device applications.
Bassariscus astutus
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Carnivora
Procyonidae
Bassariscus
Bassariscus astutus

description: Bassariscus astutus (Lichtenstein, 1830). Abh. Konigl. Akad. Wiss., Berlin, for 1827, p. 119. TYPE LOCALITY: Mexico, near city of Mexico. DISTRIBUTION: S. W. Oregon, N. Nevada, Utah, S. W. Wyoming and W. Colorado, south through California, Arizona, New Mexico and Texas (U.S.A.), to the Isthmus of Tehuantepec (Mexico); Tiburon Isl. and several other islands in the Gulf of California. COMMENT: Includes albipes, raptor and saxícola; see Hall, 1981:962-965. Records from E. Colorado, Kansas, Ohio, Louisiana, and South Carolina are probably not indicative of the present range (SK). ISIS NUMBER: 5301412003003001001.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Carnivora, pp. 244-289 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 253, DOI: 10.5281/zenodo.7352980
description: {"references": ["Hall, E. R. 1981. The mammals of North America. Second ed. John Wiley and Sons, New York, 1: 1 - 600 + 90, 2: 601 - 1181 + 90."]}
A case-cohort study of human herpesvirus 8 seropositivity and incident prostate cancer in Tobago
Creators: name: Bunker, Clareann
name: Wilson, John
name: Patrick, Alan
name: Weissfeld, Joel
name: McDonald, Alicia
name: Jenkins, Frank
Publisher: name: Columbia University
Year: 2011
Subjects: Prostate-specific antigen
Herpesvirus diseases
Prostate--Cancer
Epidemiology
Oncology
Medical sciences

description: Background: We previously reported a cross-sectional association between the presence of human herpesvirus 8 (HHV-8) serum antibodies and screen-detected prostate cancer in men living in Tobago. In the same study population, we examined the association between HHV-8 seropositivity and incident prostate cancer discovered at later screenings. Methods: In 40-81 year-old men without prostate cancer discovered at initial digital rectal examination (DRE) and prostate-specific antigen (PSA) screening, a case-cohort design measured the association between baseline HHV-8 seropositivity (modified immunofluorescence assay for antibodies against HHV-8 lytic antigens) and incident prostate cancer detected at DRE and PSA screenings three or five years later. Results: Analyses included 486 unique individuals, 96 incident prostate cancer cases, and 415 randomly selected subjects representing an at-risk cohort. By design, the random sub-cohort contained 25 incident prostate cancer cases. In the sub-cohort, the frequency of HHV-8 seropositivity increased across age groupings (40-49 years: 3.5%, 50-59 years: 13.6%, and ≥ 60 years: 22.9%). HHV-8 seropositivity was higher in men with elevated (≥ 4.0 ng/mL) than men with non-elevated PSA at initial screening (30.4% vs. 9.9% seropositive; crude odds ratio (OR) 3.96, 95% confidence interval (CI) 1.53-10.2; age-adjusted OR 2.42, 95% CI 0.91-6.47). HHV-8 seropositivity did not increase incident prostate cancer risk (age-adjusted hazard ratio (HR) 0.88, 95% CI 0.46-1.69). Conclusions: Case-cohort analysis did not identify association between HHV-8 seropositivity and incident prostate cancer. However, analyses uncovered possible association between HHV-8 and PSA (a marker of prostate inflammation). Co-occurrence of HHV-8 seropositivity and PSA elevation may explain cross-sectional association between HHV-8 and PSA screen-detected prostate cancer.
Additional file 6 of Genetic map construction and functional characterization of genes within the segregation distortion regions (SDRs) in the F2:3 populations derived from wild cotton species of the D genome
Creators: name: KIRUNGU, Joy Nyangasi
name: MAGWANGA, Richard Odongo
name: SHIRAKU, Margaret Linyerera
name: LU, Pu
name: Teame Gereziher MEHARI
name: Yuanchao XU
name: Yuqing HOU
name: AGONG, Stephen Gaya
name: ZHOU, Yun
name: Xiaoyan CAI
name: ZHOU, Zhongli
name: Kunbo WANG
name: LIU, Fang
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 6: Table S6. miRNA targets prediction
Interacting Weyl semimetals on a lattice
Creators: name: Mastropietro, Vieri
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Electron-electron interactions in a Weyl semimetal are rigorously investigated in a lattice model by non perturbative methods. The absence of quantum phase transitions is proved for interactions not too large and short ranged. The anisotropic Dirac cones persist with angles (Fermi velocities) renormalized by the interaction, and with generically shifted Fermi points. As in graphene, the optical conductivity shows universality properties: it is equal to the massless Dirac fermions one with renormalized velocities, up to corrections which are subdominant in modulus.
Joint forces of three ELIXIR Core Data Resources
Creators: name: Frentrup, Martinique
name: Reimer, Lorenz C.
name: Jäde, Antje
name: Schober, Isabel
name: Gerken, Jan
Publisher: name: Zenodo
Year: 2024

description: Building the new biodata infrastructure DSMZ Digital Diversity.

Poster presented at the ELIXIR All Hands Meeting 2024.
A new world malaria map: Plasmodium falciparum endemicity in 2010
Creators: name: Gething, Peter
name: Patil, Anand
name: Smith, David
name: Guerra, Carlos
name: Elyazar, Iqbal
name: Johnston, Geoffrey L.
name: Tatem, Andrew
name: Hay, Simon
Publisher: name: Columbia University
Year: 2011
Subjects: Medical mapping
Malaria--Epidemiology
Plasmodium falciparum
Public health
Epidemiology
Pathology

description: Background: Transmission intensity affects almost all aspects of malaria epidemiology and the impact of malaria on human populations. Maps of transmission intensity are necessary to identify populations at different levels of risk and to evaluate objectively options for disease control. To remain relevant operationally, such maps must be updated frequently. Following the first global effort to map Plasmodium falciparum malaria endemicity in 2007, this paper describes the generation of a new world map for the year 2010. This analysis is extended to provide the first global estimates of two other metrics of transmission intensity for P. falciparum that underpin contemporary questions in malaria control: the entomological inoculation rate (PfEIR) and the basic reproductive number (PfR). Methods: Annual parasite incidence data for 13,449 administrative units in 43 endemic countries were sourced to define the spatial limits of P. falciparum transmission in 2010 and 22,212 P. falciparum parasite rate (PfPR) surveys were used in a model-based geostatistical (MBG) prediction to create a continuous contemporary surface of malaria endemicity within these limits. A suite of transmission models were developed that link PfPR to PfEIR and PfR and these were fitted to field data. These models were combined with the PfPR map to create new global predictions of PfEIR and PfR. All output maps included measured uncertainty. Results: An estimated 1.13 and 1.44 billion people worldwide were at risk of unstable and stable P. falciparum malaria, respectively. The majority of the endemic world was predicted with a median PfEIR of less than one and a median PfRc of less than two. Values of either metric exceeding 10 were almost exclusive to Africa. The uncertainty described in both PfEIR and PfR was substantial in regions of intense transmission. Conclusions: The year 2010 has a particular significance as an evaluation milestone for malaria global health policy. The maps presented here contribute to a rational basis for control and elimination decisions and can serve as a baseline assessment as the global health community looks ahead to the next series of milestones targeted at 2015.
Additional file 1 of Genetic map construction and functional characterization of genes within the segregation distortion regions (SDRs) in the F2:3 populations derived from wild cotton species of the D genome
Creators: name: KIRUNGU, Joy Nyangasi
name: MAGWANGA, Richard Odongo
name: SHIRAKU, Margaret Linyerera
name: LU, Pu
name: Teame Gereziher MEHARI
name: Yuanchao XU
name: Yuqing HOU
name: AGONG, Stephen Gaya
name: ZHOU, Yun
name: Xiaoyan CAI
name: ZHOU, Zhongli
name: Kunbo WANG
name: LIU, Fang
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Details of primers used in this research
A follow-up study for left ventricular mass on chromosome 12p11 identifies potential candidate genes
Creators: name: Della-Morte, David
name: Beecham, Ashley
name: Rundek, Tatjana
name: Wang, Liyong
name: McClendon, Mark
name: Slifer, Susan
name: Blanton, Susan
name: Di Tullio, Marco R.
name: Sacco, Ralph
Publisher: name: Columbia University
Year: 2011
Subjects: subject: Cardiovascular system--Diseases--Genetic aspects
subject: Cardiovascular system--Diseases--Risk factors
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences

description: Background: Left ventricular mass (LVM) is an important risk factor for cardiovascular disease. Previously we found evidence for linkage to chromosome 12p11 in Dominican families, with a significant increase in a subset of families with high average waist circumference (WC). In the present study, we use association analysis to further study the genetic effect on LVM. Methods: Association analysis with LVM was done in the one LOD critical region of the linkage peak in an independent sample of 897 Caribbean Hispanics. Genotype data were available on 7085 SNPs from 23 to 53 MB on chromosome 12p11. Adjustment was made for vascular risk factors and population substructure using an additive genetic model. Subset analysis by WC was performed to test for a difference in genetic effects between the high and low WC subsets. Results: In the overall analysis, the most significant association was found to rs10743465, downstream of the SOX5 gene (p = 1.27E-05). Also, 19 additional SNPs had nominal p < 0.001. In the subset analysis, the most significant difference in genetic effect between those with high and low WC occurred with rs1157480 (p = 1.37E-04 for the difference in β coefficients), located upstream of TMTC1. Twelve additional SNPs in or near 6 genes had p < 0.001. Conclusions: The current study supports previously identified evidence by linkage for a genetic effect on LVM on chromosome 12p11 using association analysis in population-based Caribbean Hispanic cohort. SOX5 may play an important role in the regulation of LVM. An interaction of TMTC1 with abdominal obesity may contribute to phenotypic variation of LVM.
Contextuality supplies the magic for quantum computation
Creators: name: Howard, Mark
name: Wallman, Joel J.
name: Veitch, Victor
name: Emerson, Joseph
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum computers promise dramatic advantages over their classical counterparts, but the answer to the most basic question "What is the source of the power in quantum computing?" has remained elusive. Here we prove a remarkable equivalence between the onset of contextuality and the possibility of universal quantum computation via magic state distillation. This is a conceptually satisfying link because contextuality provides one of the fundamental characterizations of uniquely quantum phenomena and, moreover, magic state distillation is the leading model for experimentally realizing fault-tolerant quantum computation. Furthermore, this connection suggests a unifying paradigm for the resources of quantum information: the nonlocality of quantum theory is a particular kind of contextuality and nonlocality is already known to be a critical resource for achieving advantages with quantum communication. In addition to clarifying these fundamental issues, this work advances the resource framework for quantum computation, which has a number of practical applications, such as characterizing the efficiency and trade-offs between distinct theoretical and experimental schemes for achieving robust quantum computation and bounding the overhead cost for the classical simulation of quantum algorithms.
description: 5+4 pages, 2 figures
Pseudo-Dirac neutrinos via mirror-world and depletion of UHE neutrinos
Creators: name: Joshipura, Anjan S.
name: Mohanty, Subhendra
name: Pakvasa, Sandip
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a possible particle physics explanation of the non-observation of muon neutrino events at IceCube coincident with GRB gamma ray at the rates predicted by the standard Bahcall-Waxman model, in terms of neutrino oscillations. Our model is based on assuming that (a) all neutrinos are pseudo-Dirac particles and (b) there exists a mirror world interacting gravitationally with the observed world. This scenario has three sterile neutrinos associated with each flavour of ordinary neutrinos. Very tiny mass splitting between these neutrinos is assumed to arise from lepton number violating dimension five operators suppressed by the Planck scale. We show that if a mass splitting of 10^(-15) eV^2 is induced between the four mass eigenstates of a given species, then its flux will be suppressed at IceCube energies by a factor of 4 which could be the explanation of the IceCube observation that the muon neutrino flux is lower than expected. Hierarchies in mass splitting among different flavours may result in different amount of suppression of each flavour and based on this, we predict a difference in the flavour ratios of the observed neutrinos which is significantly different compared to the standard prediction of nu_e:nu_mu:nu_tau=1:1:1 which could serve as a test for this model.
Electron-spin dynamics induced by photon spins
Creators: name: Ahrens, Sven
name: Bauke, Heiko
name: Keitel, Christoph H.
name: Grobe, Rainer
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Strong rotating magnetic fields may cause a precession of the electron's spin around the rotation axis of the magnetic field. The superposition of two counterpropagating laser beams with circular polarization and opposite helicity features such a rotating magnetic field component but also carries spin. The laser's spin density, that can be expressed in terms of the lase's electromagnetic fields and potentials, couples to the electron's spin via a relativistic correction to the Pauli equation. We show that the quantum mechanical interaction of the electron's spin with the laser's rotating magnetic field and with the laser's spin density counteract each other in such a way that a net spin rotation remains with a precession frequency that is much smaller than the frequency one would expect from the rotating magnetic field alone. In particular, the frequency scales differently with the laser's electric field strength depending on if relativistic corrections are taken into account or not. Thus, the relativistic coupling of the electron's spin to the laser's spin density changes the dynamics not only quantitatively but also qualitatively as compared to the nonrelativistic theory. The electron's spin dynamics is a genuine quantum mechanical relativistic effect.
UCH SHOXLI NERV SHIKASTLANISHIDA DAVOLASH TAMOYILLARINING QIYOSIY BAHOSI
Creators: name: Shomurodov, Qahramon
name: Xamatov, Erkin
Publisher: name: Zenodo
Year: 2023

description: Statistik ma'lumotlarga ko'ra, dunyoda jarohat va baxtsiz hodisalar chastotasi o'limga olib keladigan sabablar orasida yurak-qon tomir va o'sma kasalliklaridan keyingi uchinchi o'rinni egallagan. Aholining nogironligi omillari va ishlash layoqatini vaqtincha yo'qotish tuzilmasida esa ikkinchi pog'onada turadi. Tadqiqot maqsadi yuz suyaklari sinishlarida uch shoxli nerv tolalarini zararlanish darajasi va og'irligiga qarab davolashning turli usullarini qiyosiy baholash. Og'irlik darajalariga ko'ra yuz-suyaklari sinishlari asab-qon tomir tutamlarining jarohatlarida "Neyromedin" dori vositasilari ta'sirini qonda mielin oqsili ko'rsatkichlari xolatiga ko'ra davo samaradorligini taxlil qiladigan bo'lsak, klinik va funksional tadqiqotlar natijalari yuz-jag' sohasining uch shoxli nerv periferik tarmoqlari shikastlanishi bilan kechadigan sinishlarini kompleks davolash asab tolalarining sensor va motor faoliyatini tiklash bo'yicha ijobiy natijalarni shakllantirishda samarali ekani, shuningdek, an'anaviy terapiya bilan taqqoslaganda, suyak bo'laklarining tezroq birikishiga xizmat qilishini namoyish etdi.
Supplementary figures, tables, and references from Landscape features predict the current and forecast the future geographic spread of Lyme disease
Creators: name: Gardner, Allison M.
name: Pawlikowski, Natalie C.
name: Hamer, Sarah A.
name: Hickling, Graham J.
name: Miller, James R.
name: Schotthoefer, Anna M.
name: Tsao, Jean I.
name: Allan, Brian F.
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: Lyme disease, the most prevalent vector-borne disease in North America, is increasing in incidence and geographic distribution as the tick vector, Ixodes scapularis, spreads to new regions. We re-construct the spatial-temporal invasion of the tick and human disease in the midwestern U.S., a major focus of Lyme disease transmission, from 1967 to 2018, to analyse the influence of spatial factors on the geographic spread. A regression model indicates that three spatial factors—proximity to a previously invaded county, forest cover and adjacency to a river—collectively predict tick occurrence. Validation of the predictive capability of this model correctly predicts counties invaded or uninvaded with 90.6% and 98.5% accuracy, respectively. Reported incidence increases in counties after the first report of the tick; based on this modelled relationship, we identify 31 counties where we suspect I. scapularis already occurs yet remains undetected. Finally, we apply the model to forecast tick establishment by 2021 and predict 42 additional counties where I. scapularis will likely be detected based upon historical drivers of geographic spread. Our findings leverage resources dedicated to tick and human disease reporting and provide the opportunity to take proactive steps (e.g. educational efforts) to prevent and limit transmission in areas of future geographic spread.
Προμηθέας Δεσμώτης – Προμηθέας Λυόμενος: Η εξέλιξη της Θεραπευτικής Κοινότητας του ΚΕΘΕΑ ΠΡΟΜΗΘΕΑΣ στο Σωφρονιστικό Κατάστημα Θεσσαλονίκης
Creators: name: Τσιργούλας, Απόστολος Χριστόδουλου
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Εξαρτήσεις
Ποινικό Δίκαιο
Θεραπευτικές Παρεμβάσεις Εξάρτησης εντός του Σωφρονιστικού
Θεραπευτική Κοινότητα σε Φυλακή
Εξάρτηση και Παραβατικότητα
Νόμος περί Ναρκωτικών
Addiction
Criminal Law
Therapeutic Interventions to addictive behavior within the prison
Therapeutic Community in a prison
Addiction and Delinquency
Greek Legislation regarding Drugs and drug use

description: Παράλληλα με την περίοδο προετοιμασίας και ψήφισης του νόμου 4139/2013 ξεκίνησε τις δράσεις του το Πρόγραμμα ΚΕΘΕΑ ΠΡΟΜΗΘΕΑΣ. Ο στόχος ήταν η θεραπευτική διαχείριση του διπλού στιγματισμού: της εξάρτησης και του εγκλεισμού. Οι δράσεις του προγράμματος εντάσσονταν σε ένα ευρύτερο πλαίσιο αντεγκληματικής πολιτικής, το οποίο θα διευκόλυνε την πρόσβαση του κάθε εξαρτημένου στο δικαίωμά του στην θεραπεία ακόμα και εντός του σωφρονιστικού. Η Θεραπευτική Κοινότητα ΚΕΘΕΑ ΠΡΟΜΗΘΕΑΣ στο Σωφρονιστικό Κατάστημα Θεσσαλονίκης εγκαινιάστηκε το 2015. Σχεδόν μια δεκαετία μετά, μας δίνεται η δυνατότητα μιας ασφαλούς αποτίμησης της έως τώρα δράσης, αναζητώντας περιθώρια βελτίωσης και χάραξης νέων στρατηγικών. Τα ευρήματα δείχνουν διαφορά του αριθμού των επωφελούμενων σε σχέση με τις αρχικές προσδοκίες, όπως και χαμηλά ποσοστά στους αριθμούς των επωφελούμενων που ολοκλήρωσαν εν τέλη το Πρόγραμμα. Στην συζήτηση γίνεται μια προσπάθεια ερμηνείας αυτών των αποτελεσμάτων, που κινείται σε τέσσερεις άξονες: • Διοικητική δομή του Προγράμματος και αποτύπωμά στην κοινωνία. • Σχέσεις με την διοίκηση του Καταστήματος Κράτησης. • Διαδικασίες επιλογής επωφελούμενων. • Συνύπαρξη στην Θεραπεία επωφελούμενων με διαφορετικό κίνητρο για θεραπεία.
description: During the period of preparation and passage of the 4139/2013 law regarding the control and regulation of psychoactive substances in Greece, the Therapeutic Program KETHEA PROMITHEAS was founded. The aim of the intervention was to deal therapeutically with the double stigma of drug addiction and imprisonment. It was part of a broader anti-crime policy, pursuing to enable drug addicted offenders to have access to therapy even during detention. The Therapeutic Community ΚΕΤΗΕΑ PRΟΜΙΤΗΕΑΣ of Thessaloniki Detention Center, was inaugurated in 2015. Almost a decade past that time we are able to evaluate the intervention, seeking leads for further development and new strategies. Findings suggest difference in the number of beneficiaries compared to initial expectations, as well as low rates in the numbers of beneficiaries, who eventually completed the Program. The discussion attempts to interpret these results moving along four axes: • Administrative structure of the Program and its impact on public view. • Relations of the Program with the administration of the Detention Facility. • Selection procedures of the beneficiaries • Coexistence in Treatment of beneficiaries with different motivations for treatment.
Relativistic Non-Thermal Bremsstrahlung Radiation
Creators: name: Zeković, Vladimir
name: Arbutina, Bojan
name: Dobardzić, Aleksandra
name: Pavlović, Marko
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: By applying a method of virtual quanta we derive formulae for relativistic non-thermal bremsstrahlung radiation from relativistic electrons as well as from protons and heavier particles with power-law momentum distribution $N(p)dp = k p^{-q} dp.$ We show that emission which originates from an electron scattering on an ion, represents the most significant component of relativistic non-thermal bremsstrahlung. Radiation from an ion scattering on electron, known as inverse bremsstrahlung, is shown to be negligible in overall non-thermal bremsstrahlung emission. These results arise from theory refinement, where we introduce the dependence of relativistic kinetic energy of an incident particle, upon the energy of scattered photon. In part, it is also a consequence of a different mass of particles and relativistic effects.
description: 17 pages, 1 figure, accepted for publication in IJMPA
Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo
Creators: name: Anastassiou, Dimitris
name: Rumjantseva, Viktoria
name: Cheng, Weiyi
name: Huang, Jianzhong
name: Canoll, Peter D.
name: Yamashiro, Darrell
name: Kandel, Jessica J.
Publisher: name: Columbia University
Year: 2011
Subjects: Epithelial cells
Mesenchymal stem cells
Cancer invasiveness
Cancer cells--Motility
Biomechanics
Oncology
Molecular biology

description: Background: The biological mechanisms underlying cancer cell motility and invasiveness remain unclear, although it has been hypothesized that they involve some type of epithelial-mesenchymal transition (EMT). Methods: We used xenograft models of human cancer cells in immunocompromised mice, profiling the harvested tumors separately with species-specific probes and computationally analyzing the results. Results: Here we show that human cancer cells express in vivo a precise multi-cancer invasion-associated gene expression signature that prominently includes many EMT markers, among them the transcription factor Slug, fibronectin, and α-SMA. We found that human, but not mouse, cells express the signature and Slug is the only upregulated EMT-inducing transcription factor. The signature is also present in samples from many publicly available cancer gene expression datasets, suggesting that it is produced by the cancer cells themselves in multiple cancer types, including nonepithelial cancers such as neuroblastoma. Furthermore, we found that the presence of the signature in human xenografted cells was associated with a downregulation of adipocyte markers in the mouse tissue adjacent to the invasive tumor, suggesting that the signature is triggered by contextual microenvironmental interactions when the cancer cells encounter adipocytes, as previously reported. Conclusions: The known, precise and consistent gene composition of this cancer mesenchymal transition signature, particularly when combined with simultaneous analysis of the adjacent microenvironment, provides unique opportunities for shedding light on the underlying mechanisms of cancer invasiveness as well as identifying potential diagnostic markers and targets for metastasis-inhibiting therapeutics.
Expression of HES and HEY genes in infantile hemangiomas
Creators: name: Kitajewski, Jan K.
name: Bischoff, Joyce
name: Boscolo, Elisa
name: Tong, Karen
name: Kitajewski, Alex
name: Wong, Alvin
name: Adepoju, Omotinuwe
name: Wu, June K.
Publisher: name: Columbia University
Year: 2011
Subjects: Notch proteins
Tumors in infants
Hemangiomas
Molecular biology
Obstetrics
Gynecology

description: Background: Infantile hemangiomas (IHs) are the most common benign tumor of infancy, yet their pathogenesis is poorly understood. IHs are believed to originate from a progenitor cell, the hemangioma stem cell (HemSC). Recent studies by our group showed that NOTCH proteins and NOTCH ligands are expressed in hemangiomas, indicating Notch signaling may be active in IHs. We sought to investigate downstream activation of Notch signaling in hemangioma cells by evaluating the expression of the basic HLH family proteins, HES/HEY, in IHs. Materials and Methods: HemSCs and hemangioma endothelial cells (HemECs) are isolated from freshly resected hemangioma specimens. Quantitative RT-PCR was performed to probe for relative gene transcript levels (normalized to beta-actin). Immunofluorescence was performed to evaluate protein expression. Co-localization studies were performed with CD31 (endothelial cells) and NOTCH3 (peri-vascular, non-endothelial cells). HemSCs were treated with the gamma secretase inhibitor (GSI) Compound E, and gene transcript levels were quantified with real-time PCR. Results: HEY1, HEYL, and HES1 are highly expressed in HemSCs, while HEY2 is highly expressed in HemECs. Protein expression evaluation by immunofluorescence confirms that HEY2 is expressed by HemECs (CD31+ cells), while HEY1, HEYL, and HES1 are more widely expressed and mostly expressed by perivascular cells of hemangiomas. Inhibition of Notch signaling by addition of GSI resulted in down-regulation of HES/HEY genes. Conclusions: HES/HEY genes are expressed in IHs in cell type specific patterns; HEY2 is expressed in HemECs and HEY1, HEYL, HES1 are expressed in HemSCs. This pattern suggests that HEY/HES genes act downstream of Notch receptors that function in distinct cell types of IHs. HES/HEY gene transcripts are decreased with the addition of a gamma-secretase inhibitor, Compound E, demonstrating that Notch signaling is active in infantile hemangioma cells.
Equity American Option Valuation Guide
Creators: name: Xiao, David
Publisher: name: Zenodo
Year: 2020
Subjects: equity option, American option, European option, option valuation, pricing model

description: An American option give an investor the right but not the obligation to buy a call or sell a put at a set strike price at any time prior to the contract’s expiry date. Since investors have the freedom to exercise their American options at any point during the life of the contract, they are more valuable than European options, which can only be exercised at maturity.
description: https://ia803409.us.archive.org/30/items/eq-american-1/EqAmerican-archive.pdf
Recurrent refractory Kawasaki disease
Creators: name: Costa Reis, P.
name: Nativ, S.
name: Starr, Amy Joan
name: Imundo, Lisa F.
name: Eichenfield, Andrew Howard
Publisher: name: Columbia University
Year: 2011
Subjects: Pediatric rheumatology
Mucocutaneous lymph node syndrome
Medical sciences
Pathology

description: Background: Kawasaki disease is a common childhood vasculitis. Unrelenting fever after treatment with intravenous immunoglobulin (IVIG) occurs in 10-15% of patients and is associated with a greater risk of developing coronary aneurysms. Aim: Describe a very unique case of recurrent and refractory Kawasaki disease. Case report: A 3 year old boy presented with 3 days of fever, rash, pharyngeal and gingival erythema, and swollen extremities. Laboratory investigations revealed leukocytosis, C–reactive protein 25.8 mg/dl, and erythrocyte sedimentation rate 100 mm/hr. Echocardiography disclosed diffuse dilatation of all proximal coronary arteries. The child received IVIG (2g/kg) and aspirin (100 mg/kg/d) with no response. IVIG was repeated, followed by methylprednisolone 30 mg/kg for 3 days, but the child remained febrile. Infliximab (5 mg/kg) was thereupon employed with prompt defervescence. Low-dose aspirin was continued, as well as clopidogrel. Echocardiographic findings remained stable. Six months after the initial episode, the child again presented with fever, irritability, sore throat and nuchal rigidity. Physical examination revealed cracked, swollen lips, oropharyngeal erythema, posterior cervical lymphadenopathy, and rash. Desquamation of the distal extremities was observed some days later. Aneurysms were detected, involving the left and right main coronary arteries, as well as the left anterior descending coronary. Magnetic resonance angiography of the chest and abdomen revealed no other involved vessels. The child again received IVIG, pulse methylprednisolone, and infliximab, but remained febrile and developed significant arthritis, requiring daily prednisolone. He is now asymptomatic. Conclusions: Currently, recurrent and refractory Kawasaki disease still represents a therapeutic challenge.
Conceptual and methodological challenges to measuring political commitment to respond to HIV
Creators: name: Fox, Ashley
name: Goldberg, Allison B.
name: Gore, Radhika Jayant
name: Bärnighausen, Till
Publisher: name: Columbia University
Year: 2011
Subjects: subject: Commitment (Psychology)
subject: HIV (Viruses)--Government policy
subject: Political science
subject: FOS: Political science
subject: Health services administration
subject: Medical care

description: Background: Researchers have long recognized the importance of a central government’s political “commitment” in order to mount an effective response to HIV. The concept of political commitment remains ill-defined, however, and little guidance has been given on how to measure this construct and its relationship with HIV-related outcomes. Several countries have experienced declines in HIV infection rates, but conceptual difficulties arise in linking these declines to political commitment as opposed to underlying social and behavioural factors. Methods: This paper first presents a critical review of the literature on existing efforts to conceptualize and measure political commitment to respond to HIV and the linkages between political commitment and HIV-related outcomes. Based on the elements identified in this review, the paper then develops and presents a framework to assist researchers in making choices about how to assess a government's level of political commitment to respond to HIV and how to link political commitment to HIV-related outcomes. Results: The review of existing studies identifies three components of commitment (expressed, institutional and budgetary commitment) as different dimensions along which commitment can be measured. The review also identifies normative and ideological aspects of commitment and a set of variables that mediate and moderate political commitment that need to be accounted for in order to draw valid inferences about the relationship between political commitment and HIV-related outcomes. The framework summarizes a set of steps that researchers can follow in order to assess a government's level of commitment to respond to HIV and suggests ways to apply the framework to country cases. Conclusions: Whereas existing studies have adopted a limited and often ambiguous conception of political commitment, we argue that conceiving of political commitment along a greater number of dimensions will allow researchers to draw a more complete picture of political commitment to respond to HIV that avoids making invalid inferences about the relationship between political commitment and HIV outcomes.
B170087EC-Advanced Antenna Systems Report.pdf
Creators: name: Kar, Girija Naandan
Publisher: name: figshare
Year: 2020
Subjects: subject: 100501 Antennas and Propagation
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: An antenna is a specialized transducer that converts radio-frequency(RF) into alternating current(AC) or vice-versa. There are two basic types: the receiving antenna, which intercepts RF energy and delivers AC to electronic equipment and the transmitting antenna, which is fed with AC from electronic equipment. A monopole antenna is one half of a dipole antenna, almost always mounted above some sort of ground plane. In this report we will be simulating a Monopole antenna in HFSS 13.0 with a frequency of 1.0 GHz and will observe the Polar Plot, Rectangular Plot, S Parameters and also look at the advantages and disadvantages of using monopole antennas.
Out of the White Hole: A Holographic Origin for the Big Bang
Creators: name: Pourhasan, Razieh
name: Afshordi, Niayesh
name: Mann, Robert B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: While most of the singularities of General Relativity are expected to be safely hidden behind event horizons by the cosmic censorship conjecture, we happen to live in the causal future of the classical big bang singularity, whose resolution constitutes the active field of early universe cosmology. Could the big bang be also hidden behind a causal horizon, making us immune to the decadent impacts of a naked singularity? We describe a braneworld description of cosmology with both 4d induced and 5d bulk gravity (otherwise known as Dvali-Gabadadze-Porati, or DGP model), which exhibits this feature: The universe emerges as a spherical 3-brane out of the formation of a 5d Schwarzschild black hole. In particular, we show that a pressure singularity of the holographic fluid, discovered earlier, happens inside the white hole horizon, and thus need not be real or imply any pathology. Furthermore, we outline a novel mechanism through which any thermal atmosphere for the brane, with comoving temperature of 20% of the 5D Planck mass can induce scale-invariant primordial curvature perturbations on the brane, circumventing the need for a separate process (such as cosmic inflation) to explain current cosmological observations. Finally, we note that 5D space-time is asymptotically flat, and thus potentially allows an S-matrix or (after minor modifications) AdS/CFT description of the cosmological big bang.
description: 16 pages, 3 figures
B170087EC-Artificial Intelligence Report.pdf
Creators: name: Kar, Girija Naandan
Publisher: name: figshare
Year: 2020
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: There is a lot of uncertainty in the world but agents still need to act. Probability provides a way of summarizing the uncertainty that comes from our laziness and ignorance. In this report we will be studying the use of probability in Artificial Intelligence, various probability rules and Baye's rules. Lastly connecting Baye’s Rule with uncertainty or Wumpus World.
Bassariscus sumichrasti
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Carnivora
Procyonidae
Bassariscus
Bassariscus sumichrasti

description: Bassariscus sumichrasti (Saussure, 1860). Rev. Mag. Zool. Paris, ser. 2, 12:7. TYPE LOCALITY: Mexico, Veracruz, Mirador. DISTRIBUTION: Guerrero and S. Veracruz (Mexico) to W. Panama. COMMENT: Includes montícola and variabilis; see Hall, 1981:965. PROTECTED STATUS: CITES - Appendix III (Costa Rica). ISIS NUMBER: 5301412003003002001.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Carnivora, pp. 244-289 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 253, DOI: 10.5281/zenodo.7352980
description: {"references": ["Hall, E. R. 1981. The mammals of North America. Second ed. John Wiley and Sons, New York, 1: 1 - 600 + 90, 2: 601 - 1181 + 90."]}
Dark Matter or Neutrino recoil? Interpretation of Recent Experimental Results
Creators: name: Pospelov, Maxim
name: Pradler, Josef
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The elastic nuclear recoil signal, being under intense scrutiny by multiple underground experiments, can be interpreted either as coming from the interaction of nuclei with WIMP dark matter or from the scattering of new species of MeV-energy neutrinos. The most promising model for the latter case is a neutrino $ν_b$ that interacts with baryon number, and with a flux sourced by the oscillations of regular solar $^8$B neutrinos. We re-analyze this model in light of the latest experimental results. In contrast to the light-DM interpretation of various tentative positive signals (anomalies) that is now seriously challenged by the negative results of the LUX experiment, the neutrino interpretation remains a viable explanation to most of the anomalies. Considering future prospects, we show that the superCDMS experiment alone, when equipped with Ge and Si detectors, will be able to detect $ν_b$ and discriminate the model from a light DM interpretation. In addition, we also provide the forecast for the new CRESST-II run that now operates with new detectors and diminished backgrounds.
description: 10 pages, 5 figures
Letter from Jonathan Abbatt to Mary Dilworth (later Abbatt), May 11, 1853
Creators: name: Abbatt, Jonathan, 1829-1905
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Quakers
valueUri: http://id.worldcat.org/fast/1084913
subject: Man-woman relationships--Religious aspects
valueUri: http://id.worldcat.org/fast/1007090
subject: Interpersonal relations
valueUri: http://id.worldcat.org/fast/977397
subject: Families
valueUri: http://id.worldcat.org/fast/1728849
subject: Faith
valueUri: http://id.worldcat.org/fast/1198492
subject: Courtship
valueUri: http://id.worldcat.org/fast/881873
subject: Man-woman relationships
valueUri: http://id.worldcat.org/fast/1007080
subject: Marriage
valueUri: http://id.worldcat.org/fast/1010443
subject: Quakers--Family relationships
valueUri: http://id.worldcat.org/fast/1084922

description: This letter is part of a series of courtship correspondence between Jonathan Abbatt and Mary Dilworth (later Abbatt). The Abbatt family was a Quaker family who lived in the towns and villages of Preston, Ribchester, and Garstang in Lancashire, England. The letters chronicle the courtship, discussions of faith, local events, shared sentiments, etc. Mary sometimes addressed as Polly in the letters. Please note that the months on the letters’ dates were added as numerical values rather than the month's name (e.g. 2 Mo = February). Jonathan tells Mary that addressing her as a friend is too distant for what they are now, as there is now love and esteem between them. He mentions that he hasn't heard from his sister yet, but they are planning on visiting at Mary's invitation. Jonathan tells Mary he ran into R. Jackson on the train, and he asked him all sorts of questions about George Glover and Ellen.
Supplementary Tables from Vocal convergence in a multi-level primate society: insights into the evolution of vocal learning
Creators: name: Fischer, Julia
name: Wegdell, Franziska
name: Trede, Franziska
name: Pesco, Federica Dal
name: Hammerschmidt, Kurt
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour

description: Supplementary Tables for Fischer et al. Vocal Convergence in a multi-level society
Localisation and finite-size effects in graphene flakes
Creators: name: González-Santander, C.
name: Domínguez-Adame, F.
name: Hilke, M.
name: Römer, R. A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We show that electron states in disordered graphene, with an onsite potential that induces inter-valley scattering, are localised for all energies at disorder as small as 1/6 of the band width of clean graphene. We clarify that, in order for this Anderson-type localisation to be manifested, graphene flakes of size of approximately 200 x 200 nm^2 or larger are needed. For smaller samples, due to the surprisingly large extent of the electronic wave functions, a regime of apparently extended (or even critical) states is identified. Our results complement earlier studies of macroscopically large samples and can explain the divergence of results for finite-size graphene flakes.