cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy
Creators: name: Walter, Robert Fred Henry
name: Vollbrecht, Claudia
name: Werner, Robert
name: Mairinger, Thomas
name: Schmeller, Jan
name: Flom, Elena
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: pleural mesothelioma
subject: NanoString nCounter
subject: digital gene expression analysis
subject: DNA-damage repair
subject: platin-based chemotherapy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly aggressive tumour leading to a dismal prognosis. Multimodality therapy consisting of platinum-based chemotherapy is the treatment of choice. The reasons for the rather poor efficacy of platinum compounds remain largely unknown. Material and Methods: For this exploratory mRNA study, 24 FFPE tumour specimens were screened by digital gene expression analysis. Based on data from preliminary experiments and recent literature, a total of 366 mRNAs were investigated using a Custom CodeSet from NanoString. All statistical analyses were calculated with the R i386 statistical programming environment. Results: CDC25A and PARP1 gene expression were correlated with lymph node spread, BRCA1 and TP73 expression levels with higher IMIG stage. NTHL1 and XRCC3 expression was associated with TNM stage. CHECK1 as well as XRCC2 expression levels were correlated with tumour progression in the overall cohort of patients. CDKN2A and MLH1 gene expression influenced overall survival in this collective. In the adjuvant treated cohort only, CDKN2A, CHEK1 as well as ERCC1 were significantly associated with overall survival. Furthermore, TP73 expression was associated with progression in this subgroup. Conclusion: DNA-damage response plays a crucial role in response to platin-based chemotherapeutic regimes. In particular, CHEK1, XRCC2 and TP73 are strongly associated with tumour progression. ERCC1, MLH1, CDKN2A and most promising CHEK1 are prognostic markers for OS in MPM. TP73, CDKN2A, CHEK1 and ERCC1 seem to be also predictive markers in adjuvant treated MPMs. After a prospective validation, these markers may improve clinical and pathological practice, finally leading to a patients' benefit by an enhanced clinical management.
Nitrogen - element with impacts
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2023
Subjects: subject: Stickstoff
subject: nitrogen
subject: reactive nitrogen
subject: national boundary
subject: Air
subject: Health
subject: Water

description: Nitrogen emissions from almost all sectors of society lead to risks for humans and the environment. Sustainable management of nitrogen and its compounds therefore plays a major role in achieving the UN Sustainable Development Goals (SDGs). As a milestone towards sustainable nitrogen management, the German Environment Agency proposes a upper limit of 1,000 kt nitrogen per year for Germany. The limit covers almost all sources and includes not only agriculture but also other nitrogen relevant sectors such as transport and industry. The background paper explains the background on risks, summarises the current pollution situation in Germany and evaluates existing mitigation options against the new cap. Quelle: www.umweltbundesamt.de
description: Nitrogen emissions from almost all sectors of society lead to risks for humans and the environment. Sustainable management of nitrogen and its compounds therefore plays a major role in achieving the ⁠UN⁠ Sustainable Development Goals (SDGs). As a milestone towards sustainable nitrogen management, the German Environment Agency proposes a upper limit of 1,000 kt nitrogen per year for Germany. The limit covers almost all sources and includes not only agriculture but also other nitrogen relevant sectors such as transport and industry. The background paper explains the background on risks, summarises the current pollution situation in Germany and evaluates existing mitigation options against the new cap.
The aging lung: tissue telomere shortening in health and disease
Creators: name: Everaerts, Stephanie
name: Lammertyn, Elise J.
name: Martens, Dries S.
name: De Sadeleer, Laurens J.
name: Maes, Karen
name: Van Batenburg, Aernoud A.
name: Goldschmeding, Roel
name: Van Moorsel, Coline H. M.
name: Dupont, Lieven J.
name: Wuyts, Wim A.
name: Vos, Robin
name: Gayan-Ramirez, Ghislaine
name: Kaminski, Naftali
name: Hogg, James C.
name: Janssens, Wim
name: Verleden, Geert M.
name: Nawrot, Tim S.
name: Verleden, Stijn E.
name: McDonough, John E.
name: Vanaudenaerde, Bart M.
Publisher: name: BioMed Central
Year: 2018

description: Background: Telomere shortening has been associated with several lung diseases. However, telomere length is generally measured in peripheral blood leucocytes rather than in lung tissue, where disease occurs. Consequently, telomere dynamics have not been established for the normal human lung nor for diseased lung tissue. We hypothesized an age- and disease-dependent shortening of lung tissue telomeres. Methods: At time of (re-)transplantation or autopsy, 70 explant lungs were collected: from unused donors (normal, n = 13) and patients with cystic fibrosis (CF, n = 12), chronic obstructive pulmonary disease (COPD, n = 11), chronic hypersensitivity pneumonitis (cHP, n = 9), bronchiolitis obliterans syndrome (BOS) after prior transplantation (n = 11) and restrictive allograft syndrome (RAS) after prior transplantation (n = 14). Lungs were inflated, frozen and then scanned using CT. Four tissue cores from distinct lung regions were sampled for analysis. Disease severity was evaluated using CT and micro CT imaging. DNA was extracted from the samples and average relative telomere length (RTL) was determined using real-time qPCR. Results: The normal lungs showed a decrease in RTL with age (p < 0.0001). Of the diseased lungs, only BOS and RAS showed significant RTL decrease with increasing lung age (p = 0.0220 and p = 0.0272 respectively). Furthermore, we found that RTL showed considerable variability between samples within both normal and diseased lungs. cHP, BOS and RAS lungs had significant shorter RTL in comparison with normal lungs, after adjustment for lung age, sex and BMI (p < 0.0001, p = 0.0051 and p = 0.0301 respectively). When investigating the relation between RTL and regional disease severity in CF, cHP and RAS, no association was found. Conclusion: These results show a progressive decline in telomere length with age in normal, BOS and RAS lungs. cHP, BOS and RAS lungs demonstrated shorter RTL compared to normal lungs. Lung tissue RTL does not associate with regional disease severity within the lung. Therefore, tissue RTL does not seem to fully reflect peripheral blood telomere length.
Prism
Creators: name: Lehr, Ulrike
name: Lutz, Christian
name: Ulrich, Philipp
Publisher: name: My University
Year: 2013
Subjects: Klimaschutz

description: Über die Existenz des Klimawandels und die Notwendigkeit von Klimaschutzmaßnahmen
bestehen in der wissenschaftlichen Literatur zunehmend geringere Zweifel. Die regelmäßigen
Berichte des IPCC stellen immer noch die fundamentale Basis der internationalen
Klimaschutzpolitik und zunehmend auch der Klimafolgenanpassungsforschung dar. Die
Analyse und Durchsetzung der notwendigen Maßnahmen im Detail ist jedoch häufig mit einer
umfassenden Diskussion der Kosten und Nutzen dieser Maßnahmen verbunden.
Sollen Maßnahmen zur Begrenzung der Emission von Treibhausgasemissionen vorgeschlagen
oder Anreizinstrumente zum Ergreifen dieser Maßnahmen konzipiert werden, sollten diese
auch anhand des Kostenkriteriums geplant und priorisiert werden. Hierzu werden auf der
nationalen Ebene, wo diese Politiken stattfinden, Kostenschätzungen durchgeführt. Darüber
hinaus werden kombinierte Maßnahmenpakete bewertet, wie etwa das Integrierte Klima- und
Energiepaket IEKP, die Bestandteil einer umfassenderen Klimaschutzstrategie sind. Auch die EU
hat zu den von ihr vorgeschlagenen Paketen, wie dem 20-20-20 Energie- und Klimapaket oder
der kürzlich vorgeschlagenen Verschärfung des Klimaziels die Kosten und Nutzen in
begleitenden Untersuchungen berechnen lassen.
Die vorliegende Untersuchung systematisiert die Literatur und schließt auf Empfehlungen für
eine gute Praxis, je nachdem, in welchem Stadium des politischen Entscheidungsprozesses die
Analyse der Kosten und Nutzen aus den Perspektiven verschiedener wirtschaftlicher Akteuredurchgeführt werden soll.
Quelle: Forschungsbericht
description: The existence of climate change and the necessity of mitigation measures are hardly doubted
any more in the scientific community. The IPCC reports are the solid base of international
climate change mitigation policies and are increasingly used for climate change adaption
analyses. Implementation of the measures on regional or local levels, however, is often joined
by a comprehensive discussion about costs and benefits.
Thus, measures for the reduction of greenhouse gas emissions (GHG) or incentives for this
reduction should always be prioritized and planned taking cost-benefit analyses into account.
Therefore, on the national level, where policy instruments are decided, cost estimates are
carried out. Measures and instruments often are clustered into packages and the economic
effects of the whole bundle is analysed, for example for the integrated energy and climate
package (IKEP, Germany), for the 20-20-20 package of the EC or for the recently suggested
tightening of the GHG targets in the EC.
This study tries to structure existing estimates and to deduct best practice examples for eachstage of the decision making process.
Quelle: Forschungsbericht
Supporting Concept Assessment in Engineering Design by Applying the Function Integrity Diagnosis and Documentation Method
Creators: name: Wichmann, Robert Lawrence
Publisher: name: Swinburne
Year: 2024

description: This research proposes the Function Integrity Diagnosis and Documentation (FIDD) method to support concept assessment in engineering design. It focuses on conceptual design to assess alternative design concepts for their suitability in design adaptation. The FIDD method employs system modelling with risk assessment to analyse risk to function fulfillment. The resulting Function Integrity indicator supports function reasoning of a prospective concept to compare dissimilar designs. Three empirical case studies showed that applying this method enables designers to leverage their experience in integrating novel systems into existing products and services.
Development of regiocontrolled pentadienyl indium condensations and a carbometallation-intramolecular cycloaddition synthesis of taxoids
Creators: name: Villalva, Nidia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Chemistry, General.
subject: Chemistry, Pharmaceutical.

description: The synthesis of the taxanes derivatives has been the major focus of this research. The efforts made towards the synthesis of these complex and successful drugs for the treatment of cancer have resulted in the development of efficient synthetic strategies. These approaches have arisen mainly from our studies in the carbometallation of propargyl alcohols and the development of stereoselective Lewis acid catalyzed IMDA. The application of these potential synthetic strategies has yielded very significant results. The synthesis of the tricyclic core of the taxanes (2.149) by a novel carbometallation-cycloaddition-RCM sequence was successfully achieved using readily available starting materials and mild reaction conditions. In addition, the versatile carbometallation-cycloaddition sequence allowed the synthesis of AB ring system of taxanes with different functionalities (2.126, 2.111 and 2.128). The construction of a functionalized A ring (2.84) was also accomplished. This intermediate and some of its derivatives were employed to attempt the synthesis of B ring of taxanes by RCM. Additionally, the further functionalization of AB and ABC ring-systems of taxanes was investigated. Unfortunately, the synthesis of a biological active taxane derivative was not possible. In addition, we have studied the in situ carbonyl addition oxy-Cope rearrangement of unsaturated ketones.* *Please refer to dissertation for diagrams.
Das Herkunftsnachweisregister für Strom aus erneuerbaren Energiequellen
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2017
Subjects: subject: Herkunftsnachweis
subject: Herkunftsnachweisregister
subject: Ökostrom
subject: Herkunftsnachweisregister für Strom aus erneuerbaren Energiequellen
subject: HKNR
subject: Erneuerbarer Strom
subject: Klima | Energie

description: Das Umweltbundesamt führt ein elektronisches Register mit Herkunftsnachweisen für Strom aus erneuerbaren Energiequellen. Warum und wie genau das funktioniert, erläutert dieses Faltblatt.
Neuartiger Öffentlichkeitsdialog in Verfahren mit Umweltprüfung am Beispiel bestimmter Vorhabentypen/Vorhabeneigenschaften
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Bürgerbeteiligung
subject: Konfliktbewältigung
subject: Energiewende
subject: Nachhaltigkeit | Strategien | Internationales
subject: Sustainability | Strategies | International matters

description: Das Forschungsprojekt befasst sich mit der Entwicklung einer praxisrelevanten Handreichung für Behörden für den Umgang mit einer zusätzlichen, über die gesetzlichen Vorgaben hinausgehenden Beteiligung der Bürgerinnen und Bürger bei der Planung und Genehmigung von Vorhaben im Kontext der Verwirklichung der Energiewende. Im Ergebnis des Vorhabens ist ein Leitfaden für Behördenvertreterinnen und -vertreter erarbeitet worden. Der Leitfaden wurde für fünf Vorhabentypen (Biomasse, Netze, Pumpspeicherwerke, tiefe Geothermie, Windenergie) konzipiert und enthält, neben grundsätzlichen Empfehlungen für eine effektive und effiziente Öffentlichkeitsbeteiligung, die für alle Vorhaben Relevanz haben, jeweils eine Konkretisierung für vorhabenspezifische Fragestellungen.
Quelle: www.umweltbundesamt.de

description: Das Forschungsprojekt befasst sich mit der Entwicklung einer praxisrelevanten Handreichung für Behörden für den Umgang mit einer zusätzlichen, über die gesetzlichen Vorgaben hinausgehenden Beteiligung der Bürgerinnen und Bürger bei der Planung und Genehmigung von Vorhaben im Kontext der Verwirklichung der Energiewende. Im Ergebnis des Vorhabens ist ein Leitfaden für Behördenvertreterinnen und -vertreter erarbeitet worden. Der Leitfaden wurde für fünf Vorhabentypen (⁠Biomasse⁠, Netze, Pumpspeicherwerke, tiefe Geothermie, Windenergie) konzipiert und enthält, neben grundsätzlichen Empfehlungen für eine effektive und effiziente Öffentlichkeitsbeteiligung, die für alle Vorhaben Relevanz haben, jeweils eine Konkretisierung für vorhabenspezifische Fragestellungen.
The regulation of kit ligand expression in rat granulosa cells by ovarian factors
Creators: name: Shamoon, Rita
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Biology, Molecular.

description: The aim of this research was to clarify the actions and interactions between factors implicated in the regulation of kit ligand (KITL) expression in rat granulosa cells by measuring Kitl1 and Kitl2 mRNA levels through quantitative PCR. Our findings included the observation that induction of the transcripts in primary granulosa cells by follicle-stimulating hormone (FSH), was not mimicked by dibutyryl cAMP and forskolin in spontaneously immortalized granulosa cells (SIGC). Transforming growth factor-beta1 (TGF-beta1) suppressed Kitl1 and Kitl2 mRNA levels in primary granulosa cells and SIGC - an effect mediated via Smad2 and Smad3. Exposure of primary granulosa cells to estrogen in vivo, via diethylstilbestrol (DES)-priming of immature rats and in vitro, by culturing in the presence of 17beta-estradiol, inhibited Kitl1 and Kitl2 mRNA expression, an effect mediated via TGF-beta1. Therefore, three levels of control are involved in regulating Kitl mRNA expression in the ovary: gonadotropins, local ovarian factors and steroid hormones.
Case studies in spatial inferential reasoning (Years 3 to 12) in the Technologies/Engineering curriculum
Creators: name: Cerovac, Milorad
Publisher: name: Swinburne
Year: 2024

description: Milorad’s thesis examined the ability of students to develop and share their solutions to hands-on Technologies problems of varying complexity. Technologies teachers are at the forefront of building students’ capabilities to think and act as creators and innovators. However, little is known of how these capabilities can be effectively developed. By using three hands-on engineering tasks of varying complexity, and purpose-designed assessment tools, he was able to provide a comparative measure of students’ spatial abilities, which highlighted the need for regular exposure to tactile hands-on tasks, the development of students’ technical vocabulary, and explicit teaching of how students work collaboratively.
A reconfigurable processing unit for digital circuit testing using built-in self-test techniques
Creators: name: Elbadri, Mohammed
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Engineering, Electronics and Electrical.

description: Digital circuit testing is presented in this thesis. This thesis introduces an architecture that accelerates benchmarked circuit testing. Traditionally, benchmark circuits are tested on software, because of the complexity in developing a generic hardware architecture capable of testing sequentially or concurrently. The testing is based on Built-in Self-Test (BIST) techniques. The circuit testing is accomplished by two hardware implementations, aimed at increasing execution time with respect to its counterpart, software. The implementation realized and executed in hardware, illustrates the advantages of utilizing hardware platforms for digital circuit testing and it gives a path to developing more complex benchmarked circuits; which would have higher fault coverage. The novel architecture is targeted for digital circuit testing and adaptive embedded system applications. These applications vary in their constraints (i.e. hard and soft real-time constraints) and environmental conditions (i.e. unknown and unpredictable). The novel architecture consists of a fixed hardware unit and a Reconfigurable Processor Unit (RPU). The RPU employs hardware functional blocks. These Hardware Blocks (HB) encompass logic that targets their respective applications. We realize and implement HBs that target digital circuit testing applications, by means of BIST techniques. Experimental results are presented in this thesis. In simple terms, the speedup factors are as high as 1 x 104 for sequential testing.
title: Corporate finance in the digital age
Creators: name: Jiang, Zhonghao
Publisher: name: University of Glasgow
Year: 2024
Subjects: subject: Digital age, cross-border M&As, social connectedness, CEO interview, investor disagreement, climate change exposure, mutual fund ownership.

description: This thesis, structured into three chapters, delves into novel and significant research questions in corporate finance within the digital age, employing advanced quantitative methodologies: 1. Social Connectedness and Cross-Border Mergers and Acquisitions; 2. Remote or Face-to-Face: CEO Interviews and Investor Disagreement; 3. Climate Change Exposure and Mutual Fund Ownership. Chapter 1 investigates the role of social connectedness in cross-border mergers and acquisitions (M&As). Using Facebook’s Social Connectedness Index, the chapter shows that social connectedness induces higher stock returns to acquirers’ M&A announcements. Social connectedness works through an information dissemination channel, which reduces target premiums, increases the completion rate, and facilitates long-run success. Chapter 2 examines the financial implications of CEOs’ information disclosure modalities. Using CEOs’ televised media interviews on CNBC, the chapter finds that, compared to face-to-face interviews, remote interviews are associated with larger investor disagreement around the interview date. The lack of medium richness in remote interviews can lead to increased dispersion in information interpretation among investors, resulting in larger investor disagreement. Chapter 3 documents a negative implication of firms’ climate change exposure on their mutual fund ownership, using Sauter et al. (2023)’s climate change exposure index. This thesis provides insights into the evolving corporate finance in the digital age, by employing diverse and dynamic data sources and analytical tools, such as textual analysis and bridging sociological concepts, CEO behaviors, and environmental concerns with corporate finance.
Effects of Transcranial Alternating Current Stimulation on Cognitive Functions in Healthy Young and Older Adults
Creators: name: Antonenko, Daria
name: Faxel, Miriam
name: Grittner, Ulrike
name: Lavidor, Michal
name: Floeel, Agnes
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Recently, transcranial alternating current stimulation (tACS) has emerged as a tool to enhance human cognitive processes. Here, we provide a brief summary of the rationale behind tACS-induced effects on task-relevant brain oscillations and associated cognitive functions and review previous studies in young subjects that have applied tACS in cognitive paradigms. Additionally, we present pilot data where we administered theta-tACS (6 Hz) over the temporoparietal cortex and a supraorbital reference for 20 min during implicit language learning in healthy young (mean/SD age: 22/2) and older (mean/SD age: 66/4) adults, in a sham-controlled crossover design. Linear mixed models revealed significantly increased retrieval accuracy following tACS-accompanied associative learning, after controlling for session order and learning success. These data provide the first implementation of tACS during cognitive performance in older adults and support recent studies suggesting that tACS in the theta frequency range may serve as a tool to enhance cognition, possibly through direct modulation of task-relevant brain oscillations. So far, studies have been heterogeneous in their designs, leaving a number of issues to be addressed in future research, including the setup of electrodes and optimal stimulation frequencies to be employed, as well as the interaction with age and underlying brain pathologies in specific patient populations.
A STUDY of CENTRAL GALAXY ROTATION with STELLAR MASS and ENVIRONMENT
Creators: name: Oliva Altamirano, Paola
name: Brough, Sarah
name: Tran, Kim-Vy
name: Jimmy
name: Miller, Christopher
name: Bremer, Malcom N.
name: Phillipps, Steven
name: Sharp, Rob
name: Colless, Matthew
name: Lara-López, Maritza A.
name: López-Sánchez, Ángel R.
name: Pimbblet, Kevin
name: Kafle, Prajwal R.
name: Couch, Warrick
Publisher: name: Swinburne
Year: 2024

description: We present a pilot analysis of the influence of galaxy stellar mass and cluster environment on the probability of slow rotation in 22 central galaxies at mean redshift z=0.07. This includes new integral-field observations of 5 central galaxies selected from the Sloan Digital Sky Survey, observed with the SPIRAL integral-field spectrograph on the Anglo-Australian Telescope. The composite sample presented here spans a wide range of stellar masses, 10.9
Buenoa platycnemis
Creators: name: Santos, Suzane Evaristo Dos
name: Barbosa, Julianna Freires
name: Moreira, Felipe Ferraz Figueiredo
name: Couceiro, Sheyla Regina Marques
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Notonectidae
Buenoa
Buenoa platycnemis

description: Buenoa platycnemis (Fieber, 1851)
(Fig. 29A–B)
Anisops platycnemis Fieber, 1851: 61 (original description)
Buenoa platycnemis: Kirkaldy (1904): 123 (combination change)
Distribution. Argentina (Kirkaldy 1904). Bonaire (Nieser 1967). Brazil: Amazonas (Barbosa & Nessimian 2013a), Goiás (Truxal 1957), Maranhão (Truxal 1953; Jordão et al. 2025), Mato Grosso (Nieser 1970b), Pará (Nieser 1970b; Barbosa & Nessimian 2013a; Nobre et al. 2019; present study), Pernambuco (Jordão et al. 2025), Rio de Janeiro (Kirkaldy 1904; Ribeiro et al. 1998; Nessimian & Ribeiro 2000; Barbosa et al. 2010a; Ribeiro et al. 2010), Sergipe (Jordão et al. 2025), Tocantins (Truxal 1957). Cayman Islands. Colombia. Costa Rica (Truxal 1953). Cuba (Uhler 1884). Curaçao. Guadeloupe (Nieser 1967). Haiti. Jamaica. Martinique (Truxal 1953). Mexico (Uhler 1884). Nicaragua (Lopez et al. 1998). Panama. Peru (Truxal 1953). Puerto Rico (Fieber 1851). St. Martin (Nieser 1967). United States (Uhler 1884). U.S. Virgin Islands (Fieber 1851). Trinidad & Tobago (Nieser & Alkins-Koo 1991). Venezuela (Truxal 1953).
Distribution in Pará. Belterra (Nieser 1970b), Canaã dos Carajás (Barbosa & Nessimian 2013a; Nobre et al. 2019), Itaituba (present study), Parauapebas (Barbosa & Nessimian 2013a), Santarém (present study).
Comment. Records from the United States other than from Texas and Florida correspond to other species (Truxal 1953).
Material examined. Brazil, Pará, Município de Itaituba, Poça Campo Belo, 04°16’24” S / 56°02’28” W, 26/ VII/2022, S.E. Santos col. (12 ♂, 21 ♀); Poça Lago Bom Jardim, 04°16’33” S / 56°00’18” W, 27/VII/2022, S.E. Santos col. (1 ♂). Município de Santarém, Lago Maicá, 02°28’01” S / 54°39’51” W, 27/ V /2021, E.C. Oliveira col. (1 ♂); Poça Curuá-Una, 02°48’29” S / 54°17’44” W, 05/ VI /2023, S.E. Santos col. (4 ♂, 6 ♀).
description: Published as part of Santos, Suzane Evaristo Dos, Barbosa, Julianna Freires, Moreira, Felipe Ferraz Figueiredo & Couceiro, Sheyla Regina Marques, 2025, Corixoidea and Notonectidae (Hemiptera: Heteroptera: Nepomorpha) of Pará, Brazil, with new records from the western portion of the state, pp. 275-304 in Zootaxa 5627 (2) on page 289, DOI: 10.11646/zootaxa.5627.2.3, http://zenodo.org/record/15325988
A three-dimensional haptic cataract tele-surgery simulation
Creators: name: Hamam, Abdelwahab
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Engineering, Biomedical.
subject: Engineering, Electronics and Electrical.

description: Medical simulations are becoming more advanced and more reliable in training medical students and new surgeons. Especially in the context of delicate surgeries, such as cataract surgery, the medical community is shifting from traditional medical training to sophisticated virtual reality simulations. In this thesis, we present a simulation built in a three-dimensional environment that aids in training medical residents to perform cataract surgeries. The application utilizes haptic devices as a means of interaction, which enriches the application by providing a sense of touch and force-feedback to users. In addition, we discuss our modeling of the environment and the decisions undertaken in the design. We also compare this 3D application with similar applications in terms of functionality but with different user interfaces, and mention what was the eye surgeon's reaction towards each interface in the training simulation. Finally, we conclude with future modifications of the application and describe a future direction.
La traduction du cliché dans les textes pragmatiques : définition, repérage, équivalences.
Creators: name: Nina, Armand J.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Language, Linguistics.

description: As the millennium draws to a close, post-modernism is witnessing a trend aimed at restoring respect for the sociolinguistic cliche. The translation of cliches, however, has not yet attracted comprehensive research. This thesis is not an in-depth study of the question, due to the limits inherent in an MA thesis; rather, our purport is to cover the general implications of translating cliches in pragmatic texts. Translating cliches can usually imply the same theory and practice generally adopted for translating pragmatic texts with respect to their individual contexts and situation. However, certain parameters can help discern the most appropriate path, namely, elements that are translationally pertinent, encompassing communication-specific discourse, functions, as well as the referential entropy for which cliches are blamed and which may have to be taken into account in the target text. This study ends by underlining the need to develop a new semiotic approach which would consider a cliche as an entity constituting a sign in itself, and the possibility for developing a teaching model for translating cliches suited to the undergraduate program. (Abstract shortened by UMI.)
Hippocampal Pathway Plasticity Is Associated with the Ability to Form Novel Memories in Older Adults
Creators: name: Antonenko, Darla
name: Külzow, Nadine
name: Cesarz, Magda E.
name: Schindler, Kristina
name: Grittner, Ulrike
name: Flöel, Agnes
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: learning
subject: cognitive training
subject: white matter microstructure
subject: diffusion tensor imaging
subject: fornix
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: White matter deterioration in the aging human brain contributes to cognitive decline. The fornix as main efferent hippocampal pathway is one of the tracts most strongly associated with age-related memory impairment. Its deterioration may predict conversion to Alzheimer’s dementia and its precursors. However, the associations between the ability to form novel memories, fornix microstructure and plasticity in response to training have never been tested. In the present study, 25 healthy older adults (15 women; mean age (SD): 69 (6) years) underwent an object-location training on three consecutive days. Behavioral outcome measures comprised recall performance on the training days, and on 1-day and 1-month follow up assessments. MRI at 3 Tesla was assessed before and after training. Fornix microstructure was determined by fractional anisotropy and mean diffusivity (MD) values from diffusion tensor imaging (DTI). In addition, hippocampal volumes were extracted from high-resolution images; individual hippocampal masks were further aligned to DTI images to determine hippocampal microstructure. Using linear mixed model analysis, we found that the change in fornix FA from pre- to post-training assessment was significantly associated with training success. Neither baseline fornix microstructure nor hippocampal microstructure or volume changes were significantly associated with performance. Further, models including control task performance (auditory verbal learning) and control white matter tract microstructure (uncinate fasciculus and parahippocampal cingulum) did not yield significant associations. Our results confirm that hippocampal pathways respond to short-term cognitive training, and extend previous findings by demonstrating that the magnitude of training-induced structural changes is associated with behavioral success in older adults. This suggests that the amount of fornix plasticity may not only be behaviorally relevant, but also a potential sensitive biomarker for the success of training interventions aimed at improving memory formation in older adults, a hypothesis to be evaluated in future studies.
Evaluation of potential rainwater tank outcomes using generalised equations and future performance of rainwater harvesting systems
Creators: name: Khan, Mohammad Saarim
Publisher: name: Swinburne
Year: 2024

description: Optimisation of rainwater tank outcomes has always been a challenge for the users, as the water savings depend on several factors such as annual rainfall, rainfall distribution in a year, roof area, tank size and rainwater demand. To overcome this hurdle, this research presents the development of robust equations for calculating expected annual water savings through rainwater tanks, which consist of variables like annual rainfall, rainwater demand, tank size, and roof area. Moreover, as the development of such equations for every location is a tedious task, the usefulness of using such equations for neighbouring locations warrants attention. This research investigates the spatial sensitivity of four generalised equations developed earlier for Brisbane to be used for any random location in Brisbane.
Also, due to the onslaught of climate change, the rainfall pattern is likely to get altered in future and this may affect the performance of a rainwater harvesting system (RWHS). However, studies related to the effects of climate change on RWHS are limited. This research examined the future performance of rainwater tanks in Brisbane under two different climate change scenarios: RCP4.5 (optimistic scenario) and RCP8.5 (pessimistic scenario).
Supplementary document for Mid-infrared frequency comb from a ring quantum cascade laser - 4338664.pdf
Creators: name: Meng, Bo
name: Singleton, Matthew
name: Shahmohammadi, Mehran
name: Kapsalidis, Filippos
name: wang, ruijun
name: Beck, Mattias
name: Faist, Jérôme
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: The supplemental material contains detailed information on the main manuscript.
title: ESPONDILOLISTESIS DISPLÁSICA EN EL ADULTO: Hallazgos radiológicos y revisión de la literatura
Creators: name: Bermejo Garcés, Rebeca
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Conventional radiography
subject: CT

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
1.
Describir la apariencia radiológica de la espondilolistesis displásica L5/S1 en el adulto,
haciendo énfasis en los criterios diagnósticos en radiología simple y en la TCMD. 2.
Realizar una revisión de la literatura pertinente,
recopilando y...
title: Ecografia en atención primaria
Creators: name: Perez tapia, Laia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Management

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
A partir de la recogida de datos del número de Ecografías Abdominales realizadas en el Servicio de Radiodiagnóstico solicitadas desde Atención Primaria y las realizadas en los Centros de Salud de AP Conocer el impacto de la implantación...
title: Linfomas del SNC: Hallazgos típicos y atípicos en TC y RM.
Creators: name: Villanueva Delgado, Marta
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Lymphoma

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar mediante TC y RM los hallazgos típicos y atípicos del Linfoma del...
title: Impingement Isquiofemoral, ¿Imaginación o Realidad?
Creators: name: Oca Pernas, Roque
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Oedema
subject: MR
subject: Musculoskeletal system

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir los hallazgos en RM del impingement isquiofemoral. Estudiar si existen diferencias estadísticamente significativas del espacio isquiofemoral,
cuadrado femoral y ángulo de inclinación femoral entre los casos patológicos y los casos...
Evidence for the use of complementary and alternative medicines during fertility treatment: a scoping review
Creators: name: Miner, Skye A
name: Robins, Stephanie
name: Zhu, Yu J
name: Keeren, Kathelijne
name: Gu, Vivian
name: Read, Suzanne C
name: Zelkowitz, Phyllis
Publisher: name: BioMed Central
Year: 2018

description: Background: Complementary and alternative medicines (CAM) are sometimes used by individuals who desire to improve the outcomes of their fertility treatment and/or mental health during fertility treatment. However, there is little comprehensive information available that analyzes various CAM methods across treatment outcomes and includes information that is published in languages other than English. Method: This scoping review examines the evidence for 12 different CAM methods used to improve female and male fertility outcomes as well as their association with improving mental health outcomes during fertility treatment. Using predefined key words, online medical databases were searched for articles (n = 270). After exclusion criteria were applied, 148 articles were analyzed in terms of their level of evidence and the potential for methodological and author bias. Results: Surveying the literature on a range of techniques, this scoping review finds a lack of high quality evidence that complementary and alternative medicine (CAM) improves fertility or mental health outcomes for men or women. Acupuncture has the highest level of evidence for its use in improving male and female fertility outcomes although this evidence is inconclusive. Conclusion: Overall, the quality of the evidence across CAM methods was poor not only because of the use of research designs that do not yield conclusive results, but also because results were contradictory. There is a need for more research using strong methods such as randomized controlled trials to determine the effectiveness of CAM in relation to fertility treatment, and to help physicians and patients make evidence-based decisions about CAM use during fertility treatment.
title: Optimización en la adquisición de estudios de Cardio-RM: protocolo gráfico.
Creators: name: Plasencia Martínez, Juana María
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Cardiac
subject: Cardiovascular system
subject: MR
subject: Diagnostic procedure
subject: Imaging sequences
subject: Technical aspects

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisión de los conceptos técnicos esenciales en cardio-RM de cara a entender mejor esta técnica y a llevar a cabo nuestro segundo y principal objetivo. Creación de un manual gráfico para la adquisición de estudios de cardio-RM,
elaborando un...
Transforming student support with AI : a retrieval-based generation framework for personalized support and faculty customization
Creators: name: Wang, Kevin Shukang
Publisher: name: University of British Columbia
Year: 2025

description: The rapid evolution of Natural Language Processing (NLP) has positioned Large Language Models (LLMs) like ChatGPT as transformative tools across various sectors, including education. These models offer significant potential for enhancing learning experiences through personalized assistance, yet their propensity to generate incorrect, biased, or unhelpful responses poses critical challenges for their deployment in educational contexts. The usability of AI as tutors or assistants demands better human-AI design, particularly through personalization and customization to meet diverse educational needs. The first contribution of this thesis focuses on optimizing the AI agent for education, primarily through the design of a Retrieval Augmented Generation (RAG) pipeline as the agent’s core tool. By refining its components, this research aims to ensure that AI-driven educational assistants provide more accurate and contextually relevant responses. In addition to these technical enhancements, this research introduces a system that centralizes help-seeking channels with AI to facilitate the seamless integration of the optimized RAG framework into existing educational platforms. This resulted in the integrated HelpMe system, ensuring that the enhanced RAG system’s benefits are accessible to a broader range of users without requiring extensive technical expertise. Through both quantitative and qualitative data gathered during the deployment both the queuing system and integrated system, we find significant benefits in the integrated HelpMe system as an assistive tool for educators and students. We also identify future directions and challenges in human-AI interactions within educational contexts.
Structural Performance of a steel Braced Battered Micropile Group Footing System
Creators: name: Al-Taie, Rania
Publisher: name: Swinburne
Year: 2024

description: This thesis evaluates the structural performance of a steel braced battered micropile group footing system. The first part examines the durability and service life of the steel footing components in various environments. The second part evaluates the connection interaction between two different configurations of steel plates and micropiles through finite element analysis and laboratory experiments. The last part focuses on the soil micropiles interaction using finite element software and validate with field tests results. The conclusion drawn from this study suggests that current micropiles are suitable for temporary applications and can be considered as an alternative solution in small scale projects.
Developing a Training Course to Reduce the Gap in Information and Digital Knowledge Access of Governmental Service: A Case Study of a Community in Satun Province
Creators: name: Nawapon Kewsuwan
Publisher: name: Department of Information Science, Faculty of Humanities and Social Sciences, Khon Kaen University
Year: 2024
Subjects: Training program
Information and digital knowledge
Digital literacy
Skill
Understanding and use of digital technology

description: Journal of Information Science Research and Practice, 42, 4, 1–23
Supplementary document for Optomechanical time-domain analysis based on coherent forward stimulated Brillouin scattering probing - 4344977.pdf
Creators: name: Dong, Yong Kang
name: Pang, Chao
name: Hua, Zijie
name: Zhou, Dengwang
name: Zhang, Hongying
name: Chen, Liang
name: Bao, Xiaoyi
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
Resilience, trust, and civic engagement in the post-CCSVI era
Creators: name: Benjaminy, Shelly
name: Schepmyer, Andrew
name: Illes, Judy
name: Traboulsee, Anthony
Publisher: name: BioMed Central
Year: 2018

description: Background: Scientific and financial investments in chronic cerebrospinal venous insufficiency (CCSVI) research have been made to address both the hope for and scepticism over this interventional strategy for MS. Despite limited evidence in support of the CCSVI hypothesis, the funding of clinical research was responsive to a demand by the public rarely seen in the history of medicine. We characterize patient perspectives about the CCSVI research trajectory, with particular attention to its impact on other non-pharmaceutical areas of MS research with a focus on stem cell interventions. Methods: Semi-structured interviews with 20 MS patients across Canada who did not have CCSVI interventions. Interviews were analysed for recurring themes and individual variations using the constant comparative approach. Results: Participants had a critical view of the divestment of funds from longstanding research to support CCSVI trials. They retain a sense of optimism, however, about emerging evidence for stem cell interventions for MS, and highlight the need for greater caution and conscientious communication of advances in medicine and science. Conclusions: The unrealized hopes for CCSVI challenged but did not undermine the resilience of patient communities. The narrative that unfolded highlights the importance of drawing a socially-minded space for public participation in science.
Effects of Diode Laser, Gaseous Ozone, and Medical Dressings on Enterococcus faecalis Biofilms in the Root Canal Ex Vivo
Creators: name: Bitter, Kerstin
name: Vlassakidis, Alexander
name: Niepel, Mediha
name: Hoedke, Daniela
name: Schulze, Julia
name: Neumann, Konrad
name: Moter, Annette
name: Noetzel, Joern
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The objective was to compare the antibacterial effects of adjunctive disinfection using diode laser and gaseous ozone compared to the medical dressings calcium hydroxide (Ca(OH)2) and chlorhexidine gel (CHX-Gel) on Enterococcus faecalis biofilms in human root canals ex vivo. Root canals of 180 human extracted teeth were infected by E. faecalis and divided into 3 main groups (G): G1, control; G2, instrumentation and irrigation using 0.9% NaCl; G3, instrumentation and irrigation using 1% NaOCl. In each main group, the following treatments were applied: gaseous ozone, diode laser, and medical dressings of Ca(OH)2 or CHX-Gel for 7 days (). Reduction of colony forming units (CFUs) inside the root canal of planktons and frequencies of adherent bacteria after treatment were calculated. Bacterial reduction was significantly affected by the irrigation protocol () and the disinfection method (), and a significant interaction between both factors could be observed (; ANOVA). In G3 (instrumentation using 1% NaOCl), no significant effect of disinfection methods could be demonstrated on planktonic bacteria (; ANOVA) and frequencies of adherent bacteria (; chi-square test). Instrumentation and irrigation using NaOCl combined with ozone or laser application resulted in comparable bacterial reduction on E. faecalis to the application of medical dressings.
Supplementary document for Optomechanical time-domain analysis based on coherent forward stimulated Brillouin scattering probing - 4344977.pdf
Creators: name: Dong, Yong Kang
name: Pang, Chao
name: Hua, Zijie
name: Zhou, Dengwang
name: Zhang, Hongying
name: Chen, Liang
name: Bao, Xiaoyi
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplemental Document
Going home: A study of unemployed female workers' perspectives on unemployment.
Creators: name: Hughes-Bond, Linda.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Women's Studies.

description: In spite of the recent positive economic growth, millions of Canadians continue to experience the impact of unemployment. Although half of the jobless are female, women remain seriously neglected in the unemployment literature, with the few existing studies tending to be non North-American, to focus on blue-collar workers, to rely on quantitative approaches, and to result in contradictory findings. In this qualitative study, conducted from a constructivist, feminist perspective, semistructured, in-depth individual interviews and a focus-group interview were conducted with 12 unemployed women. In an atmosphere of safety and mutual respect, the women were considered the experts best able to articulate their job loss experiences. Findings largely confirm those of earlier studies of male and female unemployment, in that job loss tends to produce negative affective reactions such as shock, fear, anger and betrayal, often followed by feelings of self-blame, low self-esteem, anxiety, and even depression. Specifically, Jahoda's (1982) deprivation model of unemployment is supported by this study in that the destructive effects of job loss appear to be linked to the loss of essential categories of experience previously provided by the institution of employment. These include: income, routine, social contacts, meaningful activity, a sense of identity, and a sense of purpose. Findings also tend to negate long-held assumptions regarding the primacy of the domestic role in women's self-definitions. Moving beyond the deprivation model, the findings of this study suggest that a relational model of unemployment might better illuminate our understanding of women's job loss experiences, in that it acknowledges the centrality of relationship in female, if not human, psychological development (Gilligan, 1996). Women's unemployment, according to this proposed model, is experienced as varying degrees of disconnection, or loss of relationship, along the dimensions outlined by Jahoda's model. The relational model also informs our understanding of other important and related issues, such as the failure of the alternative role of homemaker to ameliorate the destructive impact of unemployment, and the difficulties which many women, if not all individuals, experience during the re-employment process. Implications of a relational model for unemployment theory, for workplace policies, and for the implementation of support services and re-training programs are discussed.