cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 3 of Identification of key player genes in gene regulatory networks
Creators: name: Nazarieh, Maryam
name: Wiese, Andreas
name: Will, Thorsten
name: Hamed, Mohamed
name: Helms, Volkhard
Publisher: name: Figshare
Year: 2016
Subjects: subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: User guide. This guide contains instructions for users to use the MDS and MCDS programs to find the optimal solution in a directed network. It also includes two GRNs from breast cancer network modules which can be used as input networks for ILP programs. (PDF 45 kb)
Tropidozineus vicinus
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Tropidozineus
Tropidozineus vicinus

description: 144. Tropidozineus vicinus (Melzer, 1931) (Figure 20)
Ozineus vicinus Melzer, 1931a: 68.
Tropidozineus vicinus; Monné, M. A. & Martins, 1976: 72. Distribution. Brazil (Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Bolivia (Pando), Argentina (Misiones).
New record for Minas Gerais State.
Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, male, 27– 31.X.2013, M. L. Monné & J.P. Botero.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on pages 231-232, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Technomyrmex Mayr 1872
Creators: name: Perrichot, Vincent
name: Boudinot, Brendon E.
name: Engel, Michael S.
name: Fls
name: Xu, Chunpeng
name: Bojarski, Błażej
name: Szwedo, Jacek
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Technomyrmex

description: GENUS TECHNOMYRMEX MAYR, 1872
Type species: Technomyrmex strenuus Mayr, 1872: 147.
description: Published as part of Perrichot, Vincent, Boudinot, Brendon E., Engel, Michael S., Fls, Xu, Chunpeng, Bojarski, Błażej & Szwedo, Jacek, 2022, Ants (Hymenoptera: Formicidae) from Miocene Ethiopian amber: filling gaps in the geological record of African terrestrial biota, pp. 775-791 in Zoological Journal of the Linnean Society 196 on page 780, DOI: 10.1093/zoolinnean/zlac053, http://zenodo.org/record/7195057
Additional file 1: of The use of mosquito repellents at three sites in India with declining malaria transmission: surveys in the community and clinic
Creators: name: Eijk, Anna Van
name: Ramanathapuram, Lalitha
name: Sutton, Patrick
name: Peddy, Nandini
name: Choubey, Sandhya
name: Stuti Mohanty
name: Asokan, Aswin
name: Sangamithra Ravishankaran
name: G Priya
name: Johnson, Justin
name: Sangeetha Velayutham
name: Kanagaraj, Deena
name: Ankita Patel
name: Desai, Nisha
name: Nikunj Tandel
name: Sullivan, Steven
name: Wassmer, Samuel
name: Ranveer Singh
name: K Pradhan
name: Carlton, Jane
name: H. Srivasatava
name: Eapen, Alex
name: S. Sharma
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplemental information. Table S1: Use of repellents and nets in India as reported by some studies between 2000 and 2015. Table S2: Comparison of characteristics of census households included and not included in the survey. Table S3: Use of malaria protection in three sites in India, 2012-2015. Table S4A: Factors associated with the report of the use of a repellent at the household level (census) in Chennai. Table S4B: Factors associated with the report of the use of a repellent at the household level (census) in Nadiad. Table S4C: Factors associated with the report of the use of a repellent at the household level (census) in Raurkela. Table S5A: Factors associated with the report of the use of a repellent at the individual level (survey) in Chennai. Table S5B: Factors associated with the report of the use of a repellent at the individual level (survey) in Nadiad. Table S5C: Factors associated with the report of the use of a repellent at the individual level (survey) in Raurkela. Table S6A: Factors associated with the report of the use of a repellent among clinic patients in Chennai. Table S6B: Factors associated with the report of the use of a repellent among clinic patients in Nadiad. Table S6C: Factors associated with the report of the use of a repellent among clinic patients in Raurkela. Table S7: Malaria by use of repellent, study location and type of study. (DOCX 155 kb)
Additional file 5 of Identification of key player genes in gene regulatory networks
Creators: name: Nazarieh, Maryam
name: Wiese, Andreas
name: Will, Thorsten
name: Hamed, Mohamed
name: Helms, Volkhard
Publisher: name: Figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary. This file includes the supplementary figures and tables mentioned in the paper. (PDF 274 kb)
MOESM1 of Facile and rapid detection of respiratory syncytial virus using metallic nanoparticles
Creators: name: Valdez, Jesus
name: Swapnil Bawage
name: Gomez, Idalia
name: Shree Singh
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 60506 Virology

description: Additional file 1. UV-vis spectra for the RSV detection.
Trypanidius dimidiatus Thomson 1860
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Trypanidius
Trypanidius dimidiatus

description: 145. Trypanidius dimidiatus Thomson, 1860
Trypanidius dimidiatus Thomson, 1860: 8.
Distribution. Brazil (Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Argentina (Misiones).
Specimens examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, female, 27– 31.X.2013, M.L. Monné & J.P. Botero; female, 08–12.XII.2014, J.P. Botero, A. Carelli, M. Cupello & D. Souza.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 232, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
MOESM3 of Facile and rapid detection of respiratory syncytial virus using metallic nanoparticles
Creators: name: Valdez, Jesus
name: Swapnil Bawage
name: Gomez, Idalia
name: Shree Singh
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 3. UV-vis spectra for the specificity and cross-reactivity experiments for adenovirus.
Urgleptes amoenulus
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Urgleptes
Urgleptes amoenulus

description: 146. Urgleptes amoenulus (Bates, 1863)
Lepturges amoenula Bates, 1863: 368.
Urgleptes amoenula; Gilmour, 1962: 21.
Distribution. Brazil (Bahia, Minas Gerais, Rio de Janeiro). Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, male. XII.1974, M.A. Monné.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 232, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
MOESM2 of Facile and rapid detection of respiratory syncytial virus using metallic nanoparticles
Creators: name: Valdez, Jesus
name: Swapnil Bawage
name: Gomez, Idalia
name: Shree Singh
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. UV-vis spectra for the specificity and cross-reactivity experiments for P. aeruginosa.
Additional file 1: of Intestinal parasite infections and associated risk factors in communities exposed to wastewater in urban and peri-urban transition zones in Hanoi, Vietnam
Creators: name: Fuhrimann, Samuel
name: Winkler, Mirko
name: Pham-Duc, Phuc
name: Do-Trung, Dung
name: Schindler, Christian
name: Utzinger, Jürg
name: Guéladio Cissé
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Univariate logistic regression models for intestinal parasitic infections and self-reported signs. Table S1. Results of univariate logistic regression analysis for soil-transmitted helminth infections (Ascaris lumbricoides, Trichuris trichiura and hookworm) in a cross-sectional survey in the Than Tri district, Hanoi, between April and June 2014. Table S2. Results of univariate logistic regression analysis for Trichuris trichiura infections in a cross-sectional survey in the Than Tri district, Hanoi, between April and June 2014. Table S3. Results of univariate logistic regression analysis for hookworm infections in a cross-sectional survey in the Than Tri district, Hanoi, between April and June 2014. Table S4. Results of univariate logistic regression analysis for self-reported 14-days diarrhoea in a cross-sectional survey in the Than Tri district, Hanoi, between April and June 2014. Table S5. Results of univariate logistic regression analysis for self-reported skin problems in a cross-sectional survey in the Than Tri district, Hanoi, between April and June 2014. Table S6. Results of univariate logistic regression analysis for self-reported eye problems in a cross-sectional survey in the Than Tri district, Hanoi, between April and June 2014. (DOCX 106 kb)
Ravavy Fisher 2009
Creators: name: Perrichot, Vincent
name: Boudinot, Brendon E.
name: Engel, Michael S.
name: Fls
name: Xu, Chunpeng
name: Bojarski, Błażej
name: Szwedo, Jacek
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Ravavy

description: GENUS RAVAVY FISHER, 2009
Type species: Ravavy miafina Fisher, 2009: 47, figs 6, 7b.
description: Published as part of Perrichot, Vincent, Boudinot, Brendon E., Engel, Michael S., Fls, Xu, Chunpeng, Bojarski, Błażej & Szwedo, Jacek, 2022, Ants (Hymenoptera: Formicidae) from Miocene Ethiopian amber: filling gaps in the geological record of African terrestrial biota, pp. 775-791 in Zoological Journal of the Linnean Society 196 on page 782, DOI: 10.1093/zoolinnean/zlac053, http://zenodo.org/record/7195057
Urgleptes freudei Gilmour 1959
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Urgleptes
Urgleptes freudei

description: 147. Urgleptes freudei Gilmour, 1959
Urgleptes freudei Gilmour, 1959: 8.
Distribution. Brazil (Minas Gerais).
Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, female, 02– 04.XI.1972, F.M. Oliveira.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 232, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 1: Figure S1. of Fluorescence ImmunoPrecipitation (FLIP): a Novel Assay for High-Throughput IP
Creators: name: Mita, Paolo
name: Tenzin Lhakhang
name: Donghui Li
name: Eichinger, Daniel
name: Fenyo, David
name: Boeke, Jef
Publisher: name: Figshare
Year: 2016
Subjects: Biochemistry
Cell Biology
Molecular Biology
Biotechnology

description: Mass spectrometry of tryptic peptides of YFP fusion proteins recovered from upper and lower bands of HES-1 expressed the HuEV-A vector. Figure S2. Mass spectrometry of tryptic peptides of YFP fusion proteins recovered from upper and lower bands of URI as in Figure S1. Figure S3. Standard curve of YFP amounts versus fluorescence reading (excitation 475 nm, emission 527 nm). Figure S4. a) HeLa cells were plated and transfected with Fugene-HD (Promega) in different size wells according with the parameters reported in the table. b) After lysis of the cells in each of the wells, the YFP fluorescence of 10 ml of solution used for IP was 2 measured. Figure S5. Tet-ON HeLa cells were transfected with the HuEV-A construct encoding the target protein with an N-terminal FLAG, YFP (Venus) and V5 tag under a tet-inducible promoter. (PDF 5435 kb)
Metabolic engineering of industrial yeast strains to minimize the production of ethyl carbamate in grape and Sake wine
Creators: name: Dahabieh, Matthew Solomon
Publisher: name: University of British Columbia
Year: 2008

description: During alcoholic fermentation Saccharomyces cerevisiae metabolizes L-arginine to ornithine and urea. S. cerevisiae can metabolize urea through the action of urea amidolyase, encoded by the DUR1,2 gene; however, DUR1,2 is subject to nitrogen catabolite repression (NCR) in the presence of high quality nitrogen sources during fermentation. Being cytotoxic at high concentrations, urea is exported into wine where it spontaneously reacts with ethanol, and forms the carcinogen ethyl carbamate (EC). Urea degrading yeast strains were created by integrating a linear cassette containing the DUR1,2 gene under the control of the S. cerevisiae PGK1 promoter and terminator signals into the URA3 locus of the Sake yeast strains K7 and K9. The ‘self-cloned’ strains K7EC- and K9EC- produced Sake wine with 68% less EC. The Sake strains K7EC- and K9EC- did not efficiently reduce EC in Chardonnay wine due to the evolutionary adaptation of said strains to the unique nutrients of rice mash; therefore, the functionality of engineered yeasts must be tested in their niche environments as to correctly characterize new strains. S. cerevisiae possesses an NCR controlled high affinity urea permease (DUR3). Urea importing yeast strains were created by integrating a linear cassette containing the DUR3 gene under the control of the PGK1 promoter and terminator signals into the TRP1 locus of the yeast strains K7 (Sake) and 522 (wine). In Chardonnay wine, the urea importing strains K7D3 and 522D3 reduced EC by 7% and 81%, respectively; reduction by these strains was equal to reduction by the urea degrading strains K7EC- and 522EC-. In Sake wine, the urea degrading strains K7EC- and 522EC- reduced EC by 87% and 84% respectively, while the urea importing strains K7D3 and 522D3 were significantly less capable of reducing EC (15% and 12% respectively). In Chardonnay and Sake wine, engineered strains that constitutively co-expressed DUR1,2 and DUR3 did not reduce EC more effectively than strains in which either gene was expressed solely. Uptake of 14C-urea under non-inducing conditions was enhanced in urea importing strains; parental strains failed to incorporate any 14C-urea thus confirming the functionality of the urea permease derived from the integrated DUR3 cassette.
Additional file 1: of A novel approach to evaluating the UK childhood immunisation schedule: estimating the effective coverage vector across the entire vaccine programme
Creators: name: Crowe, Sonya
name: Utley, Martin
name: Walker, Guy
name: Panovska-Griffiths, Jasmina
name: Grove, Peter
name: Pagel, Christina
Publisher: name: Figshare
Year: 2015
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: The eight plausible immunisation schedules (GP visits). (DOCX 54.9 kb)
Urgleptes pusillus
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Urgleptes
Urgleptes pusillus

description: 148. Urgleptes pusillus (Melzer, 1932)
Lepturges pusillus Melzer, 1932a: 231.
Urgleptes pusillus; Gilmour, 1962: 21.
Distribution. Brazil (Minas Gerais, Rio de Janeiro, São Paulo, Rio Grande do Sul). Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, male, 02– 04.XII.1972, F.M. Oliveira.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 232, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 1: of Loss of cerebellar neurons in the progression of lentiviral disease: effects of CNS-permeant antiretroviral therapy
Creators: name: WĂ¤Chter, Christian
name: Eiden, Lee
name: Nedye Naumann
name: Depboylu, Candan
name: Weihe, Eberhard
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Figure S1. Colocalization of IBA-1/SIV gp41. Figure S2. Breakdown of BBB. Table S1. Neuroinflammatory activity score. PDF 526 kb)
Additional file 13: Table S11. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Sedative agents, analgesic agents and sedative/analgesic delivery regimens and their reported frequency of use in the national survey by units that did and did not participate in the point prevalence study. (PDF 86 kb)
Urgleptes villiersi Gilmour 1962
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Urgleptes
Urgleptes villiersi

description: 149. Urgleptes villiersi Gilmour, 1962
Urgleptes villiersi Gilmour, 1962: 21.
Type locality. Brazil, Minas Gerais: Caraça. Distribution. Brazil (Minas Gerais, Rio de Janeiro, Paraná). Described from Serra de Caraça (Gilmour, 1962: 21).
Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, male, XII.1974, O. Roppa.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 232, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 2: of â  Itâ  s a complex meshâ  - how large-scale health system reorganisation affected the delivery of the immunisation programme in England: a qualitative study
Creators: name: Chantler, Tracey
name: Saumu Lwembe
name: Saliba, Vanessa
name: Thara Raj
name: Mays, Nicholas
name: Ramsay, Mary
name: Mounier-Jack, Sandra
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Immunisation service managers and partners interview topic guid. This file provides the range of topics and questions that were covered in interviews with people involved in commissioning, managing or assuring the immunisation programme at local level. (PDF 332 kb)
Additional file 8: Table S6. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: National survey: factors determining the choice of sedative/analgesic agents reported by units. (PDF 61 kb)
Additional file 3: of â  Itâ  s a complex meshâ  - how large-scale health system reorganisation affected the delivery of the immunisation programme in England: a qualitative study
Creators: name: Chantler, Tracey
name: Saumu Lwembe
name: Saliba, Vanessa
name: Thara Raj
name: Mays, Nicholas
name: Ramsay, Mary
name: Mounier-Jack, Sandra
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Immunisation service providers interview topic guid. This file provides the range of topics and questions that were covered in interviews with health professionals involved in delivering immunisations in primary care and as part of community care organisations. (PDF 315 kb)
Aegoschema adspersum
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Aegoschema
Aegoschema adspersum

description: 150. Aegoschema adspersum (Thomson, 1860)
Aegomorphus adspersus Thomson, 1860: 337.
Aegoschema adspersum; Lane, 1938: 109.
Distribution. Brazil (Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo). Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, female, XI– XII.2013, Padre Lauro Palú.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 232, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 2: Figure S2. of Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons
Creators: name: Mamada, Naomi
name: Tanokashira, Daisuke
name: Hosaka, Ai
name: Fuyuki Kametani
name: Tamaoka, Akira
name: Araki, Wataru
Publisher: name: Figshare
Year: 2015
Subjects: Biochemistry
Cell Biology
Molecular Biology
Neuroscience

description: Effects of chloroquine on BACE1 levels and immunoreactivities in primary neurons. (A) Primary neurons were treated with or without 25 μM chloroquine (CQ) for 1 day, followed by Western blot analysis with anti-BACE1. Relative levels of BACE1 were quantified and graphed. Data represent means ± SEM of three samples from two separate experiments. *p
Fannie Mae's National Housing Survey Monthly Home Purchase Sentiment Index (HPSI) and Key Indicators - July, 2024 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2024

description: Economy on right or wrong track (3); personal financial situation (1); good or bad time to buy a house (3); good or bad time to sell a house (3); expect to move (1); direction house prices will go (3); direction rental prices will go (3); direction mortgage rates will go (1); difficulty getting a mortgage (1); home ownership (2).
Naturally occurring variations in defensive burying behavior are associated with differences in central neuropeptide expression in the male rat
Creators: name: Linfoot, Ian
Publisher: name: University of British Columbia
Year: 2008

description: The shock prod defensive burying test has proven incredibly reliable and instrumental in determining the underpinnings of normal anxiety in rodents. Largely ignored in tests of defensive burying, however, is the capacity for individual animals to display marked variations in active and passive coping behaviors. To unmask the neurobiological correlates of this behavioral differentiation, rats were exposed to a mousetrap that was remotely triggered upon approach to remove the quality of pain. This design invited striking variations in defensive burying behavior levels, in which some rats either buried robustly or showed little to no levels of defensive burying. Furthermore, differences in burying behavior were associated with marked differences in the central expression of arginine vasopressin (AVP) and oxytocin (OT). Thus, relative to animals showing no significant levels of defensive burying activity, rats showing sustained elevations in defensive burying expressed higher levels of AVP mRNA and increased numbers of androgen receptor positive cells in the medial amygdala and posterior bed nuclei of the stria terminalis, brain regions that integrate emotional appraisal and sensory information. In contrast, animals showing little to no defensive burying responses expressed relatively higher levels of AVP and OT mRNA within the supraoptic nucleus and subregions of the paraventricular nucleus of the hypothalamus responsible for neuroendocrine and autonomic function. CRH mRNA levels did not vary as a function of burying activity in the central nucleus of the amygdala, the anterior division of the bed nuclei of the stria terminalis, nor in the paraventricular nucleus. These findings suggest a role for central AVP and OT in mediating differential defensive behaviors, and demonstrate the utility of using a pain free test of conditioned defensive burying as a framework for exploring individual differences in behavioral coping and neuroendocrine capacity.
Cotycicuiara nivaria Martins & Galileo 2010
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Cotycicuiara
Cotycicuiara nivaria

description: 151. Cotycicuiara nivaria Martins & Galileo, 2010 (Figure 21)
Cotycicuiara nivaria Martins & Galileo, 2010: 4.
Type locality. Brazil, Minas Gerais: Catas Altas (Serra do Caraça). Distribution. Brazil (Bahia, Minas Gerais, Espírito Santo).
Described from Serra de Caraça (Martins & Galileo, 2010: 4).
Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, female, 21– 25.X.2014, M.L. Monné, J.P. Botero, A. Carelli & M. Cupello.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 233, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Exalphus zellibori
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Exalphus
Exalphus zellibori

description: 152. Exalphus zellibori (Lane, 1955) (Figure 22)
Alphus zellibori Lane, 1955: 290.
Exalphus zellibori; Restello, Ianuzzi & Marinoni, 2001: 298. Distribution. Brazil (Espírito Santo, Rio de Janeiro, São Paulo). New record for Minas Gerais State.
Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, female, 03– 06.XII.2013, A. Carelli & J.P. Botero.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 234, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 4: Table S1. of Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state
Creators: name: Navarra, Angelica
name: Musto, Anna
name: Gargiulo, Anna
name: Petrosino, Giuseppe
name: Pierantoni, Giovanna
name: Fusco, Alfredo
name: Russo, Tommaso
name: Parisi, Silvia
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology

description: Sequences of the oligonucleotides used for q-PCR. (PDF 44Â kb)
Additional file 1: of Production, secretion and purification of a correctly folded staphylococcal antigen in Lactococcus lactis
Creators: name: Samazan, Frédéric
name: Bachra Rokbi
name: Seguin, Delphine
name: Telles, Fabienne
name: Gautier, Valérie
name: Richarme, Gilbert
name: Chevret, Didier
name: Varela, Paloma
name: Velours, Christophe
name: Poquet, Isabelle
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Table S1. Primers used in this study
Hedypathes betulinus
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Hedypathes
Hedypathes betulinus

description: 153. Hedypathes betulinus (Klug, 1825)
Lamia (Acanthocinus) betulina Klug, 1825: 462.
Acanthoderes betulina; Laporte, 1840: 461.
Hedypathes betulinus; Heyne & Taschenberg, 1907: 243.
Distribution. Brazil (Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Paraguay, Argentina (Misiones, Corrientes).
Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, female, 13– 18.III.2015, Carvalho & Gouvea.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 234, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 3: Table S1. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: National survey: unit characteristics by response. (PDF 69 kb)
Report on Social and Legal Implications and Challenges Related to OS
Creators: name: Bentzen, Heidi Beate
name: Konach, Teodora
name: Mezinska, Signe
Publisher: name: Zenodo
Year: 2023

description: In WP2, social and legal aspects of Open Science were investigated. Details are provided in D2.1, D2.2, and D2.3. The following is a summary of the main findings and recommendations:
Oreodera quinquetuberculata
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Oreodera
Oreodera quinquetuberculata

description: 154. Oreodera quinquetuberculata (Drapiez, 1820)
Lamia 5–tuberculata Drapiez, 1820: 328.
Oreodera 5–tuberculata; White, 1855: 349.
Oreodera quinquetuberculata; Gemminger in Gemminger & Harold, 1873: 3140. Lamia trinodosa Germar, 1823: 471.
Distribution. Brazil (Alagoas, Ceará, Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Bolivia (Santa Cruz), Paraguay, Argentina. Specimens examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, male, 2 females, 27–31.X.2013, M.L. Monné & J.P. Botero; 2 males, 03–06.XII.2013, A. Carelli & J.P. Botero; 2 males, female, 21–25.X.2014, M.L. Monné, J.P. Botero, A. Carelli & M. Cupello; male, 08–12.XII.2014, J.P. Botero, A. Carelli, M. Cupello & D. Souza.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 234, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 1: Table S1. of Interpreting outcome following foot surgery in people with rheumatoid arthritis
Creators: name: Backhouse, Michael
name: Vinall-Collier, Karen
name: Redmond, Anthony
name: Helliwell, Philip
name: Anne-Maree Keenan
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 60506 Virology

description: Evolution of codes used in thematic analysis. (DOC 80Â kb)
Oreodera vulgata Monne, M. A. & Fragoso 1988
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Oreodera
Oreodera vulgata

description: 155. Oreodera vulgata Monné & Fragoso, 1988
Oreodera vulgata Monné, M. A. & Fragoso, 1988: 827.
Distribution. Brazil (Goiás, Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina), Paraguay.
Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, male, 27– 31.X.2013, M.L. Monné & J.P. Botero.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 234, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Additional file 12: Table S10. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Sedation score/scale in use reported in the national survey by units that did and did not participate in the point prevalence study. (PDF 7 kb)
Aboriginal forest tenure and governance in British Columbia : exploring alternatives from a Stellat'en First Nation community perspective
Creators: name: Weber, Sarah Elizabeth
Publisher: name: University of British Columbia
Year: 2008

description: The purpose of this research is to contribute to the identification of appropriate forest tenure and governance designs that are in congruence with Aboriginal values, interests and rights. The research is highly relevant to current societal deliberations on sustainable forest management as well as to the future of the forest sector in Canada. First Nations culture and ways of life are intimately and inextricably tied to the land. Some eighty percent of Canada’s First Nations communities are situated in productive forest regions (NAFA 2003). Even so, First Nations have been largely excluded from forest development and planning activities. Furthermore, the provincial policy emphasis on industrial timber production may not be consistent with Aboriginal forest values. This community-based research takes a participatory approach to forest policy analysis. The work is conducted in partnership with the Stellat’en First Nation and Carrier Sekani Tribal Council in central British Columbia. Stellat’en criteria for forest tenure and governance are identified in a series of workshops and interviews. These criteria are then applied in the analysis of four alternative models: the Community Ecosystem Trust, the Gitanyow joint land use planning model, BC Community Forest Agreements and Aboriginal reservations in the United States. The results indicated that Stellat’en have three main goals regarding forest tenure and governance: protect the traditional territory for future generations, protect Stellat’en culture and support Stellat’en economic self-determination. Implementation of the Stellat’en vision calls for a greater emphasis on ecological and cultural values in forest management, devolution of decision making authority to First Nations, reallocation of harvesting rights and redistribution of wealth generated by forest activities. The Stellat’en perspective emphasizes co-existence and stewardship. Evaluation of the four alternative models provided useful insights for progressive tenure and governance design. All four models had positive aspects to contribute, as well as shortcomings. The models are not mutually exclusive. Since each model addresses different management and institutional functions, they could be combined into a new system for the future.
Additional file 1 of Genome-wide gene expression and RNA half-life measurements allow predictions of regulation and metabolic behavior in Methanosarcina acetivorans
Creators: name: Peterson, Joseph
name: ShengShee Thor
name: Kohler, Lars
name: Kohler, Petra
name: Metcalf, William
name: Luthey-Schulten, Zaida
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Suppementary Information. Methods, results, discussion, figures and tables supplemental to the main text. (PDF 9707 KB)
Additional file 1: Figure S1. of Two-port approached thoracoscopic carina reconstruction using natural bronchial bifurcation
Creators: name: Qiu, Tong
name: Yandong Zhao
name: Jianfang Song
name: Fu, Bo
name: Yunpeng Xuan
name: Wenjie Jiao
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: The surgical incisions. Figure S2. (A) Follow-up CT scan 6Â months after surgery showed clear airways without recurrence. (B) Follow-up bronchoscopy 1Â months after surgery showed the neocarina (the white arrow indicated the granulomatous hyperplasia). (C) The same bronchoscopy showed the normal distal right upper bronchus. (DOCX 1549 kb)
Additional file 10: Table S8. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Characteristics of patients in Case Mix Programme units at the time of the point prevalence study (1400 on 11 December 2013) by units that did and did not participate in the point prevalence study. (PDF 80 kb)
Additional file 6: Table S4. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: National survey: first-choice analgesic agent reported by units. (PDF 61 kb)
Oreodera zikani Melzer 1930
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Oreodera
Oreodera zikani

description: 156. Oreodera zikani Melzer, 1930 (Figure 23)
Oreodera (?) zikani Melzer, 1930: 196.
Distribution. Brazil (Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo). Specimen examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, male, XII.1962, F.M. Oliveira.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 234, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Spring comes early to Jiaocheng Mountain (交城山春早)
Creators: name: Zhu Tao 祝涛
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Agriculture
valueUri: http://id.worldcat.org/fast/801355
subject: Landscape
subject: Modernization

description: Landscape painting of Jiaocheng Mountain in Shanxi includes images of modernity. Created by 祝涛 Zhu Tao, penname Zhuqiao 竹樵. Price indecipherable.
Additional file 11: Table S9. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Outcome and length of stay for patients in Case Mix Programme units on the day of the point prevalence study (1400 on 11 December 2013) by units that did and did not participate in the point prevalence study. (PDF 71 kb)
Additional file 17: Table S15. of National survey and point prevalence study of sedation practice in UK critical care
Creators: name: Richards-Belle, Alvin
name: Canter, Ruth
name: G. Power
name: Robinson, Emily
name: Reschreiter, Henrik
name: Wunsch, Hannah
name: Harvey, Sheila
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Point prevalence study: characteristics, outcomes and length of stay of sedated and non-sedated patients with validated Case Mix Programme data (n = 50 units). (PDF 86 kb)
Plistonax inopinatus Lane 1960
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Plistonax
Plistonax inopinatus

description: 157. Plistonax inopinatus Lane, 1960
Plistonax inopinatus Lane, 1960: 47.
Distribution. Brazil (Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina). Specimens examined. BRAZIL, Minas Gerais: Mun. Catas Altas, RPPN Serra do Caraça, 1350 m, 4 females, 27– 31.X.2013, M.L. Monné & J.P. Botero; female, 03–06.XII.2013, A. Carelli & J.P. Botero; female, 21–25.X.2014, M.L. Monné, J.P. Botero, A. Carelli & M. Cupello.
description: Published as part of Monné, Miguel A., 2017, New species and new records of Cerambycidae (Insecta, Coleoptera) from RPPN Sanctuary of Caraça, Minas Gerais, Brazil, pp. 201-262 in Zootaxa 4319 (2) on page 234, DOI: 10.11646/zootaxa.4319.2.1, http://zenodo.org/record/889107
Delineating the molecular mechanisms regulating chondrogenesis
Creators: name: Karamboulas, Konstantina
Publisher: name: University of British Columbia
Year: 2008

description: Sox9, (SRY-type HMG box), has been shown to play a critical role throughout chondrogenesis. Haploinsufficiency of Sox9 in humans leads to a skeletal malformation syndrome known as campomelic dysplasia. To understand the regulation of Sox9 during chondrogenesis, the developing mouse limb was used to identify and characterize regulatory regions within the Sox9 promoter. Luciferase-based reporter assays in mouse revealed a proximal promoter spanning – 2 kb from the transcriptional start site, while mobility shift assays demonstrated that a CCAAT motif is involved in the transactivation of Sox9. Moreover, luciferase-based reporter assays revealed a proximal promoter spanning – 4 kb in Fugu rubripes, and potential regulatory regions spanning the remainder of the promoter. Comparison of mammalian Sox9 upstream intergenic sequences to that of Fugu has identified 5 conserved regions that are contained within 18 kb of upstream Fugu sequence. Analysis of the transcriptional activity of these sequences has led to the identification of regulatory elements within the Sox9 promoter. Several studies also provide evidence of a role for wingless (WNT) and bone morphogenetic (BMP) signaling molecules in the regulation of chondrogenesis. TCF/LEF-LacZ reporter mice show activated canonical WNT signaling distributed throughout the embryonic age (E) 9.5 forelimb. At later stages, LacZ expression becomes confined to distal regions of the limb bud. Previous studies have demonstrated that canonical WNTs inhibit chondrogenesis. Our studies demonstrate that treatment of cultures derived from E11.5 proximal limb buds with the canonical WNT, WNT3a, inhibits chondrogenesis. However, treatment of cultures derived from E9.5 and distal E11.5 limb buds with WNT3a stimulates chondrogenesis. Quantitative PCR (qPCR) also demonstrates that WNT3a modulates a number of genes expressed throughout chondrogenesis. To gain insights into BMP function in the early limb, we have characterized BMP action in sub-populations of cells from the E10.5 limb. Surprisingly, BMPs were found to inhibit cartilage formation in immature cells, while promoting cartilage formation in more mature cells. Transcriptional profiling coupled with qPCR and time course analyses revealed that the extent of induction of Gatas by BMPs was associated with its stimulatory versus inhibitory activity. Further, SOX9 activity was inhibited following over-expression of Gatas.