cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Algebraic intersection for translation surfaces in the stratum $\mathcal{H}(2)$
Creators: name: Cheboui, Smaïl
name: Kessi, Arezki
name: Massart, Daniel
Publisher: name: arXiv
Year: 2020
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37D40, 37D50

description: We study the quantity $\mbox{KVol}$ defined as the supremum, over all pairs of closed curves, of their algebraic intersection, divided by the product of their lengths, times the area of the surface. The surfaces we consider live in the stratum $\mathcal{H}(2)$ of translation surfaces of genus $2$, with one conical point. We provide an explicit sequence $L(n,n)$ of surfaces such that $\mbox{KVol}(L(n,n)) \longrightarrow 2$ when $n$ goes to infinity, $2$ being the conjectured infimum for $\mbox{KVol}$ over $\mathcal{H}(2)$.
description: 8 pages, 3 figures. arXiv admin note: text overlap with arXiv:2007.10847
An anomalous Ty1 structure attributed to an error in reverse transcription.
Creators: name: Swanstrom, R
name: Company, M
name: Errede, B
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: We have determined the nucleotide sequence of both delta elements of a Ty1 transposon inserted near the CYC7 gene in the Saccharomyces cerevisiae CYC7-H2 mutant. The upstream delta element in this Ty1 has an unusual inverted repeat structure that may have been formed by an error during reverse transcription.
title: Travailler avec les requérants d’asile
title: paradoxe – complexité, quels enjeux professionnels pour les soignants ?
titleType: Subtitle
Creators: name: Bissig, Yaëlle
name: Mayreder, Sarah
Publisher: name: Unknown
Year: 0
Subjects: subject: droit d'asile
subject: migrant
subject: soignant
subject: pratique professionnelle

description: Ce travail porte sur la pratique quotidienne des soignants s’occupant de requérants d’asile et se propose d’examiner leurs conditions de travail et leurs stratégies d’adaptation dans un contexte politique défavorable aux étrangers. L’objectif de la recherche est de vérifier la présence des concepts de paradoxe, complexité et résistance auprès des professionnels travaillant dans le cadre des soins infirmiers donnés aux requérants d’asile. La méthodologie choisie pour ce type de recherche est une démarche hypothético-déductive, utilisant l’entretien semi-dirigé comme outil de recueil de données. Le jury a particulièrement apprécié le traitement rigoureux dans la méthodologie et le dépouillement des résultats ainsi que l'ouverture à d'autres espaces professionnels de réflexion.
Effects of progressive depletion of TCM1 or CYH2 mRNA on Saccharomyces cerevisiae ribosomal protein accumulation.
Creators: name: Fried, H M
name: Nam, H G
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: When present in excess, the mRNAs for Saccharomyces cerevisiae ribosomal proteins L3 and L29 are translated less efficiently, so that synthesis of these proteins remains commensurate with that of other ribosomal proteins (N.J. Pearson, H.M. Fried, and J.R. Warner, Cell 29:347-355, 1982; J.R. Warner, G. Mitra, W.F. Schwindinger, M. Studeny, and H.M. Fried, Mol. Cell. Biol. 5:1512-1521, 1985). We used a yeast strain with a conditionally transcribed derivative of the L3 gene to deplete cells progressively of L3 mRNA. In this case translation of L3 mRNA did not become more efficient so that L3 was not maintained at a normal level. Even when there was an initial excess of L3 mRNA, interruption of its further transcription produced an immediate drop in L3 synthesis, suggesting that the translational efficiency of preexisting mRNA cannot be altered. Lack of L3 synthesis afforded an opportunity to examine coordinate accumulation of other ribosomal proteins. Without L3, apparent synthesis of several 60S subunit proteins diminished, and 60S subunits did not assemble. A similar phenomenon occurred when, in a second strain, synthesis of ribosomal protein L29 was prevented. Loss of 60S subunit assembly was accompanied by a destabilization of some 60S ribosomal protein mRNAs. These data suggest that synthesis of some S. cerevisiae ribosomal proteins may be regulated posttranscriptionally as a function of the extent to which they are assembled.
Dressing method and quadratic bundles related to symmetric spaces. Vanishing boundary conditions
Creators: name: Valchev, Tihomir
Publisher: name: arXiv
Year: 2014
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We consider quadratic bundles related to Hermitian symmetric spaces of the type SU(m+n)/S(U(m)x U(n)). The simplest representative of the corresponding integrable hierarchy is given by a multi-component Kaup-Newell derivative nonlinear Schroedinger equation which serves as a motivational example for our general considerations. We extensively discuss how one can apply Zakharov-Shabat's dressing procedure to derive reflectionless potentials obeying zero boundary conditions. Those could be used for one to construct fast decaying solutions to any nonlinear equation belonging to the same hierarchy. One can distinguish between generic soliton type solutions and rational solutions.
description: 18 pages
title: Les enfants et leurs représentations de l'alimentation
title: quelles compétences infirmières en promotion de la santé face à l’obésité?
titleType: Subtitle
Creators: name: Salvi, Stéphanie
Publisher: name: Unknown
Year: 0
Subjects: subject: enfant
subject: comportement alimentaire
subject: infirmière scolaire
subject: promotion de la santé
subject: obésité
subject: rôle infirmier

description: Cette recherche a pour but d’explorer les représentations qu’ont les enfants autour de l’alimentation afin de comprendre leur influence sur leurs choix et leur comportement alimentaire, ceci dans une perspective de promotion de la santé face à la problématique actuelle de l’obésité infantile. Ce travail propose des pistes de réflexion, à l’attention des infirmières scolaires notamment, qui prennent en compte les différents résultats de cette recherche. C’est une recherche exploratoire et de type qualitatif. La récolte des données a été faite par le biais d’entretiens semi-structurés, auprès de quatre enfants qui âgés de 8 à 11 ans concernant leurs représentations et leurs besoins face à l’alimentation Les principaux résultats de cette recherche montrent que ces enfants ont passablement de connaissances, qu’ils sont confrontés à différentes influences qui ont des conséquences sur leur comportement alimentaire et qu’ils ont des demandes face à l’alimentation. Le jury a apprécié la bibliographie riche et actualisée.
(:unas) unassigned
Creators: name: (:Unkn) Unknown
Publisher: name: Universita' degli Studi di Salerno
Year: 2024

description: In ambito cristiano, la lettera pastorale, indiriz zata principalmente ai cattolici di un determinato territorio, è vista come un atto linguistico vinco lato da regole. Questo tipo di discorso religioso è stato spesso paragonato ai discorsi ispirati alla retorica antica, e soprattutto all'eloquenza dei grandi padri del cristianesimo: San Paolo e Sant'Agostino. Analizzata secondo i metodi e i concetti delle figure retoriche, questa forma di scrittura è stata analizzata alla luce della tradi zione per chiarirne la natura e comprendere le re gole compositive sottostanti, in vista degli effetti di persuasione e di obbligo che le sono propri. At traverso l'analisi di una lettera pastorale dei ve scovi francesi ai fedeli cattolici di Francia, pubbli cata l'8 novembre 2022, il presente studio si pro pone di mostrare la portata della giustificazione teologica dell'esortazione, tenendo conto degli elementi retorici che la compongono. Questi sono evidenziati alla luce dell'enfasi prevalentemente paolina che influenza il discorso religioso in gene rale e questa lettera in particolare, che affronta i temi della morte, dell'eutanasia e della comunità caratterizzata dalla fratellanza cristiana.
description: In the Christian context, the pastoral letter, pri marily addressed to Catholics in a specific terri tory, is considered a linguistic act bound by rules. This type of religious discourse has often been lik ened to speeches inspired by ancient rhetoric, par ticularly the eloquence of Christianity's great fa thers: St. Paul and St. Augustine. Analysed through the methods and concepts of rhetorical figures, this form of writing has been scrutinized in light of tradition to clarify its nature and grasp the underlying compositional rules, aiming for persuasive and obligatory effects inherent to it. Through the analysis of a pastoral letter from the French bishops to the Catholic faithful of France, published on November 8, 2022, this study en deavoursto demonstrate the theological justifica tion of the exhortation, while considering the rhe torical elements that comprise it. These are high lighted in the context of the predominantly Paul ine emphasis influencing religious discourse in general and this letter in particular, which ad dresses themes of death, euthanasia, and a com munity characterized by Christian brotherhood.
Inheritance of DNA methylation in Coprinus cinereus.
Creators: name: Zolan, M E
name: Pukkila, P J
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: We examined the inheritance of 5-methylcytosine residues at a centromere-linked locus in the basidiomycete Coprinus cinereus. Although methylated and unmethylated tracts were inherited both mitotically and meiotically the lengths of these tracts were variable. This variation was not confined to any one phase of the life cycle of the organism, and it usually involved the simultaneous de novo methylation of at least four HpaII-MspI sites. We also found that the higher levels of methylation at this locus were transmitted through meiosis, regardless of the level of methylation of the homologous chromosome.
Resonance $X(3960)$ as a hidden charm-strange scalar tetraquark
Creators: name: Agaev, S. S.
name: Azizi, K.
name: Sundu, H.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We investigate features of the hidden charm-strange scalar tetraquark $c \overline{c}s\overline{s}$ by calculating its spectral parameters and width, and we compare the obtained results with the mass and width of the resonance $ X(3960)$ discovered recently in the LHCb experiment. We model the tetraquark as a diquark-antidiquark state $X=[cs][\overline{c}\overline{s}]$ with spin-parities $J^{\mathrm{PC}}=0^{++}$. The mass and current coupling of $X$ are calculated using the QCD two-point sum rules by taking into account various vacuum condensates up to dimension $10$. The width of the tetraquark $X$ is estimated via the decay channels $X \to D_{s}^{+}D_{s}^{-}$ and $X \to η_{c} η^{(\prime)}$. The partial widths of these processes are expressed in terms of couplings $G$, $g_1$ and $g_2$ which describe the strong interactions of particles at the vertices $XD_{s}^{+}D_{s}^{-}$, $ Xη_{c}η^{\prime}$ and $Xη_{c}η$, respectively. Numerical values of $G$, $g_1$ and $g_2$ are evaluated by employing the three-point sum rule method. Comparing the results $m=(3976 \pm 85)~\mathrm{MeV}$ and $Γ_{ \mathrm{X}}=(42.2 \pm 12.0)~\mathrm{MeV}$ obtained for parameters of the tetraquark $X$ and experimental data of the LHCb Collaboration, we conclude that the resonance $X(3960)$ can be considered as a candidate to a scalar diquark-antidiquark state.
description: 13 Pages, 5 Figures and 1 Table
On equal-input and monotone Markov matrices
Creators: name: Baake, Michael
name: Sumner, Jeremy
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J10

description: The practically important classes of equal-input and of monotone Markov matrices are revisited, with special focus on embeddability, infinite divisibility, and mutual relations. Several uniqueness results for the classic Markov embedding problem are obtained in the process. To achieve our results, we need to employ various algebraic and geometric tools, including commutativity, permutation invariance and convexity. Of particular relevance in several demarcation results are Markov matrices that are idempotents.
description: 33 pages; final version with various small adjustments
Microscopic description of $α$, $2α$, and cluster decays of $^{216-220}$Rn and $^{220-224}$Ra
Creators: name: Zhao, J.
name: Ebran, J. -P.
name: Heitz, L.
name: Khan, E.
name: Mercier, F.
name: Niksic, T.
name: Vretenar, D.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Alpha and cluster decays are analyzed for heavy nuclei located above $^{208}$Pb on the chart of nuclides: $^{216-220}$Rn and $^{220-224}$Ra, that are also candidates for observing the $2 α$ decay mode. A microscopic theoretical approach based on relativistic Energy Density Functionals (EDF), is used to compute axially-symmetric deformation energy surfaces as functions of quadrupole, octupole and hexadecupole collective coordinates. Dynamical least-action paths for specific decay modes are calculated on the corresponding potential energy surfaces. The effective collective inertia is determined using the perturbative cranking approximation, and zero-point and rotational energy corrections are included in the model. The predicted half-lives for $α$-decay are within one order of magnitude of the experimental values. In the case of single $α$ emission, the nuclei considered in the present study exhibit least-action paths that differ significantly up to the scission point. The differences in alpha-decay lifetimes are not only driven by Q values, but also by variances of the least-action paths prior to scission. In contrast, the $2 α$ decay mode presents very similar paths from equilibrium to scission, and the differences in lifetimes are mainly driven by the corresponding Q values. The predicted $^{14}$C cluster decay half-lives are within three orders of magnitudes of the empirical values, and point to a much more complex pattern compared to the alpha-decay mode.
description: 9 pages, 13 figures
title: Corporate identity and piercing the corporate veil: comparative perspectives from the United States, United Kingdom and Germany
Creators: name: Macharashvili, Nata
Year: 2023

description: Der Schwerpunkt dieser Arbeit liegt auf der Analyse der Gründe und der Rechtspraxis für die Durchbrechung des Unternehmensschleiers in den Vereinigten Staaten, dem Vereinigten Königreich und Deutschland sowie auf der Darstellung der Mängel und Probleme der aktuellen Doktrin in den oben genannten Gerichtsbarkeiten und der Bereitstellung von Lösungen und Empfehlungen zu diesem Thema. Diese Arbeit bietet einen Überblick über die Doktrin der Durchbrechung des Unternehmensschleiers und konzentriert sich dabei auf den rechtlichen und wirtschaftlichen Ansatz zur beschränkten Haftung. Anschließend skizziert diese Arbeit das positive wirtschaftliche und rechtliche Paradoxon der beschränkten Haftung. In dieser Arbeit werden außerdem die Konzepte der Durchbrechung des Unternehmensschleiers in den Vereinigten Staaten, im Vereinigten Königreich und in Deutschland sowie die Arten von Gläubigern, die Grundvoraussetzungen für die Anwendung der Doktrin und die damit verbundene Rechtspraxis erörtert.
description: The focus of this thesis is to analyse the grounds and judicial practises of piercing the corporate veil in the United States, the United Kingdom and Germany, as well as to present the flaws and problems of the current doctrine in the aforementioned jurisdictions, while providing solutions and recommendations on this topic. This thesis provides an overview of the doctrine of piercing the corporate veil, focusing on the legal and economic approach to restricted liability. Following that, this thesis outlines the positive economic and legal paradox of limited liability. This thesis further discusses the concepts of piercing the corporate veil in the United States, the United Kingdom, and Germany, as well as the sorts of creditors, the fundamental preconditions for using the doctrine, and related judicial practise.
Sur quelles ressources une personne non-professionnelle s’appuie-t-elle lorsqu’on lui confie des soins et quelles sont lesconditions à garantir pour que les besoins et la sécurité des personnes dépendantes soient assurés ?
Creators: name: Sermier, Emilie
Publisher: name: Unknown
Year: 0
Subjects: subject: handicap mental
subject: bénévolat
subject: accompagnement
subject: soins
subject: sécurité

description: Pour des raisons financières, la part de personnes non-professionnelles dans le milieu des soins est de plus en plus importante (EMS, établissements pour handicapés, etc). Cela pose la question de savoir si ces travailleurs disposent de ressources internes et externes suffisantes pour assurer les besoins et la sécurité des personnes prises en charge. Ce mémoire vise à définir à quelles conditions la mobilisation des ressources internes et externes des non-professionnels est possible ; comment favoriser l’émergence de nouvelles connaissances, voire compétences, afin d’accroître les moyens extérieurs pouvant être mobilisés et de répondre aux besoins et à la sécurité des personnes prises en charge ? Cette recherche se construit sur une démarche de type qualitative utilisant comme source de savoirs les interviews effectués dans divers contextes de soins (handicapés physiques et/ou mentaux, personnes vieillissantes, camps pour handicapés) et des apports théoriques sur les différents thèmes théoriques développés : communication, travail d’équipe, compétence, professionnalisation.
A Computer-Assisted Study of Red Coral Population Dynamics
Creators: name: Kamimoto, Sayomi
name: Kim, Hye Kyung
name: Sander, Evelyn
name: Wanner, Thomas
Publisher: name: arXiv
Year: 2020
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: Primary: 37G15, 37M20, 65G20, 65P30, Secondary: 37B35, 37C70, 65G30, 92D25, 92D40

description: We consider a 13-dimensional age-structured discrete red coral population model varying with respect to a fitness parameter. Our numerical results give a bifurcation diagram of both equilibria and stable invariant curves of orbits. We observe that not only for low levels of fitness, but also for high levels of fitness, populations are extremely vulnerable, in that they spend long time periods near extinction. We then use computer-assisted proofs techniques to rigorously validate the set of regular and bifurcation fixed points that have been found numerically.
description: 31 pages, 12 figures
title: Peter Singer versus Leonardo Boff
Creators: name: Kaymaz, Merve
Year: 2023

description: Die vorliegende Masterarbeit richtet sich an zwei bedeutsame Denker, die sich mit der Thematik der Tierethik befasst haben: Peter Singer und Leonardo Boff. Im Zuge der Arbeit werden die tierethischen Positionen von Peter Singer und Leonardo Boff dargestellt, wobei der Fokus auf dem Vergleich der beiden tierethischen Ansätze liegt. Das Ziel meiner Arbeit besteht darin, die Tierethik im Hinblick auf die utilitaristische Philosophie Singers sowie das theologische Konzept Boffs zu beleuchten und diese beiden Perspektiven miteinander zu vergleichen. Die Forschungsfragen der Masterarbeit lauten: Welche Unterschiede und Gemeinsamkeiten weisen Peter Singers und Leonardo Boffs tierethische Ansätze auf? Welche didaktisch-methodischen Überlegungen ergeben sich aus den tierethischen Ansätzen von Peter Singer und Leonardo Boff für den Ethikunterricht? Des Weiteren sollen die ethischen Auffassungen Singers und Boffs im Rahmen dieser Arbeit aus pädagogischer und ethisch-didaktischer Perspektive analysiert werden. Somit fokussiert sich meine Arbeit auch darauf, wie die Ansätze von Peter Singer und Leonardo Boff in der heutigen Zeit für den Ethikunterricht in Relevanz gebracht werden können.
description: This master thesis is aimed to the most eminent personalities, which made tremendous efforts to study and research animal ethics: Peter Singer and Leonardo Boff. In this regard Peter Singer and Leonardo Boff are presenting aspects of these animal ethics, with the focused attention on differences and deviations of the existing two approaches. My study is aiming to investigate, understand and compare Peter Singers utilitarian theory against Leonardo Boffs theological approach: Following research questions have been used: What kind of difference and affinities do exist between Peter Singers and Leonardo Boffs approaches? Which didactic and methodological considerations could be derived from the animal ethic approaches of Peter Singer and Leonardo Boff for the ethic class or education? Also, the ethical perceptions of Singer and Boff will be analyzed from a pedagogical and ethical-didactic perspective. Finally my research focuses on the question, how the approaches of Peter Singer und Leonardo Boff can be used for ethics education today.
Context Aware Dynamic Traffic Signal Optimization
Creators: name: Khandwala, Kandarp
name: Sharma, Rudra
name: Rao, Snehal
Publisher: name: arXiv
Year: 2014
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Conventional urban traffic control systems have been based on historical traffic data. Later advancements made use of detectors, which enabled the gathering of real time traffic data, in order to reorganize and calibrate traffic signalization programs. Further evolvement provided the ability to forecast traffic conditions, in order to develop traffic signalization programs and strategies precomputed and applied at the most appropriate time frame for the optimal control of the current traffic conditions. We, propose the next generation of traffic control systems based on principles of Artificial Intelligence and Context Awareness. Most of the existing algorithms use average waiting time or length of the queue to assess an algorithms performance. However, a low average waiting time may come at the cost of delaying other vehicles indefinitely. In our algorithm, besides the vehicle queue, we use fairness also as an important performance metric to assess an algorithms performance.
Existe-t-il un lien entre le sponsoring sportif par des entreprises productrices de boissons alcoolisées et la consommation des sportifs en Suisse romande ?
Creators: name: Lachat, Florence
name: Meister, Mathieu
Publisher: name: Unknown
Year: 0
Subjects: subject: sport
subject: publicité
subject: consommation
subject: alcool
subject: prévention
subject: Suisse romande

description: Cette recherche de type hypotetico-déductif et quantitatif a pour but de vérifier l'existence d'un lien entre la consommation d'alcool d'un sportif et le fait d'être sponsorisé par une entreprise productrice de boissons alcoolisées. L'objectif à plus long terme est la prévention des conduites à risques liées à la consommation d'alcool et de promotion de la santé. L'hypothèse avancée soutient que l'environnement a une influence sur la survenue de conduite à risque face à l'alcool. Concrètement : la promotion d'entreprises productrices de boissons alcoolisées amène une hausse de la fréquence et de la quantité de boissons alcoolisées consommées. Le jury a relevé le questionnement très intéressant et novateur pour les soins infirmiers ainsi qu'une démarche méthodologique cohérente.
The Geometry of r-adaptive meshes generated using Optimal Transport Methods
Creators: name: Budd, C. J.
name: Russell, R. D.
name: Walsh, E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: The principles of mesh equidistribution and alignment play a fundamental role in the design of adaptive methods, and a metric tensor M and mesh metric are useful theoretical tools for understanding a methods level of mesh alignment, or anisotropy. We consider a mesh redistribution method based on the Monge-Ampere equation, which combines equidistribution of a given scalar density function with optimal transport. It does not involve explicit use of a metric tensor M, although such a tensor must exist for the method, and an interesting question to ask is whether or not the alignment produced by the metric gives an anisotropic mesh. For model problems with a linear feature and with a radially symmetric feature, we derive the exact form of the metric M, which involves expressions for its eigenvalues and eigenvectors. The eigenvectors are shown to be orthogonal and tangential to the feature, and the ratio of the eigenvalues (corresponding to the level of anisotropy) is shown to depend, both locally and globally, on the value of the density function and the amount of curvature. We thereby demonstrate how the optimal transport method produces an anisotropic mesh along a given feature while equidistributing a suitably chosen scalar density function. Numerical results are given to verify these results and to demonstrate how the analysis is useful for problems involving more complex features, including for a non-trivial time dependant nonlinear PDE which evolves narrow and curved reaction fronts.
description: arXiv admin note: substantial text overlap with arXiv:1402.5453
Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region.
Creators: name: Herskowitz, I
name: Jensen, R
name: Zoller, M J
name: Errede, B
name: Burke, J
name: Russell, D W
name: Smith, M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: The HO gene product of Saccharomyces cerevisiae is a site-specific endonuclease that initiates mating type interconversion. We have determined the nucleotide sequence of a 3,129-base-pair (bp) segment containing HO. The segment contains a single long open reading frame encoding a polypeptide of 586 amino acids, which has unusual (unbiased) codon usage and is preceded by 762 bp of upstream region. The predicted HO protein is basic (16% lysine and arginine) and is calculated to have a secondary structure that is 30% helical. The corresponding transcript is initiated approximately 50 nucleotides prior to the presumed initiation codon. Insertion of an Escherichia coli lacZ gene fragment into the putative HO coding segment inactivated HO and formed a hybrid HO-lacZ gene whose beta-galactosidase activity was regulated by the mating type locus in the same manner as HO (repressed by a 1-alpha 2). Upstream regions of 1,360 and 762 bp conferred strong repression; 436 bp led to partial constitutivity and 301 bp to full constitutivity. Thus, DNA sequences that confer repression of HO by a1-alpha 2 are at least 250 nucleotides upstream of the transcription start point and are within 436 nucleotides of the HO initiation codon. The progressive loss of repression suggests that both the -762 to -436 and the -436 to -301 intervals contain sites for regulation by a1-alpha 2. The HO gene contains two distinct regions that promote autonomous replication of plasmids in S. cerevisiae. These regions contain sequences that are homologous to the two conserved sequences that are associated with ARS activity.
The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposons.
Creators: name: Edgell, M H
name: Hardies, S C
name: Comer, M B
name: Padgett, R W
name: Hutchison, C A
name: Shehee, W R
name: Loeb, D D
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: The complete nucleotide sequence of a 6,851-base pair (bp) member of the L1Md repetitive family from a selected random isolate of the BALB/c mouse genome is reported here. Five kilobases of the element contains two overlapping reading frames of 1,137 and 3,900 bp. The entire 3,900-bp frame and the 3' 600 bp of the 1,137-bp frame, when compared with a composite consensus primate L1 sequence, show a ratio of replacement to silent site differences characteristic of protein coding sequences. This more closely defines the protein coding capacity of this repetitive family, which was previously shown to possess a large open reading frame of undetermined extent. The relative organization of the 1,137- and 3,900-bp reading frames, which overlap by 14 bp, bears resemblance to protein-coding, mobile genetic elements. Homology can be found between the amino acid sequence of the 3,900-bp frame and selected domains of several reverse transcriptases. The 5' ends of the two L1Md elements described in this report have multiple copies, 4 2/3 copies and 1 2/3 copy, of a 208-bp direct tandem repeat. The sequence of this 208-bp element differs from the sequence of a previously defined 5' end for an L1Md element, indicating that there are at least two different 5' end motifs for L1Md.
Transcriptional analysis of Ty1 deletion and inversion derivatives at CYC7.
Creators: name: Company, M
name: Errede, B
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1986

description: One class of Ty insertion mutation in Saccharomyces cerevisiae activates expression of adjacent structural genes. The CYC7-H2 mutation, in which a Ty1 element is inserted 5' to the iso-2-cytochrome c coding region of CYC7, causes a 20-fold increase in CYC7 expression. Deletion analysis of CYC7-H2 has shown that distal regions of the Ty1 element are not essential for the transcriptional activation at CYC7. In this report, we have analyzed Ty1 and CYC7 RNA from two CYC7-H2 deletion derivative genes to determine whether a direct correlation exists between transcription of Ty1 and transcription of the adjacent gene. Assuming that all Ty1 elements in the genome are transcribed equally, amounts of CYC7-H2 deletion derivative Ty1 RNA were found to be at least fivefold lower than the amount estimated for the average Ty1 element. These same Ty1 deletion derivatives caused a 20-fold increase in adjacent CYC7 expression. This finding suggests that the mechanism by which Ty1 activates adjacent gene expression does not require normal levels of Ty1 transcription. Two inversion derivatives of the CYC7-H2 Ty1 have also been analyzed. These derivatives did not produce any iso-2-cytochrome c or any normal CYC7 mRNA. Instead they were found to produce a Tyl-CYC7 fusion RNA. Consistent with our findings on CYC7-H2 Ty1 transcription, the amount of the fusion RNA was very low. In addition, the Ty1 inversion derivatives produced a new RNA that mapped to sequences upstream from the inverted Ty1 segment. Similar to Ty1 insertions that activate transcription, the new RNA was found to be transcribed away from Ty1.
Current-induced forces in nanosystems: A hierarchical equations of motion approach
Creators: name: Rudge, Samuel L.
name: Ke, Yaling
name: Thoss, Michael
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A new approach to calculating current-induced forces in charge transport through nanosystems is introduced. Starting from the fully quantum mechanical hierarchical equations of motion formalism, a timescale separation between electronic and vibrational degrees of freedom is used to derive a classical Langevin equation of motion for the vibrational dynamics as influenced by current-induced forces, such as the electronic friction. The resulting form of the friction is shown to be equivalent to previously derived expressions. The numerical exactness of the hierarchical equations of motion approach, however, allows the investigation of transport scenarios with strong intrasystem and system-environment interactions. As a demonstration, the electronic friction of three example systems is calculated and analyzed: a single electronic level coupled to one classical vibrational mode, two electronic levels coupled to one classical vibrational mode, and a single electronic level coupled to both a classical and quantum vibrational mode.
Surface Flux Patterns on Planets in Circumbinary Systems, and Potential for Photosynthesis
Creators: name: Forgan, Duncan H.
name: Mead, Alexander
name: Cockell, Charles S.
name: Raven, John A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Recently, the Kepler Space Telescope has detected several planets in orbit around a close binary star system. These so-called circumbinary planets will experience non-trivial spatial and temporal distributions of radiative flux on their surfaces, with features not seen in their single-star orbiting counterparts. Earthlike circumbinary planets inhabited by photosynthetic organisms will be forced to adapt to these unusual flux patterns. We map the flux received by putative Earthlike planets (as a function of surface latitude/longitude and time) orbiting the binary star systems Kepler-16 and Kepler-47, two star systems which already boast circumbinary exoplanet detections. The longitudinal and latitudinal distribution of flux is sensitive to the centre of mass motion of the binary, and the relative orbital phases of the binary and planet. Total eclipses of the secondary by the primary, as well as partial eclipses of the primary by the secondary add an extra forcing term to the system. We also find that the patterns of darkness on the surface are equally unique. Beyond the planet's polar circles, the surface spends a significantly longer time in darkness than latitudes around the equator, due to the stars' motions delaying the first sunrise of spring (or hastening the last sunset of autumn). In the case of Kepler-47, we also find a weak longitudinal dependence for darkness, but this effect tends to average out if considered over many orbits. In the light of these flux and darkness patterns, we consider and discuss the prospects and challenges for photosynthetic organisms, using terrestrial analogues as a guide.
description: 26 pages, 43 figures, accepted for publication in the International Journal of Astrobiology
(:unas) unassigned
Creators: name: (:Unkn) Unknown
Publisher: name: Universita' degli Studi di Salerno
Year: 2024

description: Il saggio esplora la complessità dell’utopia pulviscolare e dello spazio urbano nell’opera di Italo Calvino. Concentrandosi sull’analisi dettagliata delle zone di silenzio e sulla complessità di comunicazione nei personaggi, si approfondisce la manifestazione di tali elementi in opere significative. All’interno di questo contesto, città utopiche e città distopiche si alternano, plasmando un paesaggio letterario complesso e in costante evoluzione. Tale frammentazione intrinseca a questa dinamica richiama la natura profondamente labirintica della scrittura calviniana, enfatizzata dal persistente rovesciamento prospettico. La narrazione di calvino, intrisa di immagini poetiche, diviene uno strumento espressivo che, nel suo rapporto con Leopardi, espone la molteplicità di percezione nello spazio.
description: The essay explores the complexity of pulvis colar utopia and urban space in Italo Calvino’s works. Focusing on the detailed analysis of zones of silence and the complexities of communication among characters, such elements get enhanced in Calvino’s significant works. Within this context, utopian and dystopian cities alternate, shaping a complex and ever evolving literary landscape. The intrinsic fragmentation of this dynamic echoes the deeply twisted nature of Calvino’s writing, emphasized by the persistent reversal perspective. Calvino’s narrative epic, infused with poetic imagery, becomes an expressive tool that , in its relationship with Leopardi, reveals the multiplicity of perceptions in space.
Model-Guided Synthesis of Inductive Lemmas for FOL with Least Fixpoints
Creators: name: Murali, Adithya
name: Peña, Lucas
name: Blanchard, Eion
name: Löding, Christof
name: Madhusudan, P.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: Recursively defined linked data structures embedded in a pointer-based heap and their properties are naturally expressed in pure first-order logic with least fixpoint definitions (FO+lfp) with background theories. Such logics, unlike pure first-order logic, do not admit even complete procedures. In this paper, we undertake a novel approach for synthesizing inductive hypotheses to prove validity in this logic. The idea is to utilize several kinds of finite first-order models as counterexamples that capture the non-provability and invalidity of formulas to guide the search for inductive hypotheses. We implement our procedures and evaluate them extensively over theorems involving heap data structures that require inductive proofs and demonstrate the effectiveness of our methodology.
description: Published at OOPSLA 2022
Comment accompagner les parents qui apprennent, à la maternité, que leur enfant est né avec un handicap ?
Creators: name: Genoud, Christelle
Publisher: name: Unknown
Year: 0
Subjects: subject: naissance
subject: handicap
subject: adaptation
subject: relation soignant-famille

description: Cette étude qualitative, de type exploratoire descriptive, a pour but de découvrir les différentes stratégies adaptatives que les parents mettent en place, à la Maternité, lorsqu’ils apprennent que leur enfant est né avec un handicap. On s’aperçoit que la naissance d’un enfant handicapé va plonger ces parents dans un état de choc et déstabiliser leur vie sociale, familiale et professionnelle. Ils devront alors mettre en place des stratégies, que l’on nomme aussi coping, pour faire face à cette nouvelle réalité et retrouver un certain équilibre et bien-être. Ils pourront ainsi s’adapter à leur rôle de parents. La méthode d’investigation utilisée a consisté à conduire des entretiens semi-dirigés auprès de cinq parents d’enfant handicapé. On peut notamment constater que dans ces situations, l’infirmière peut avoir une influence sur les facteurs environnementaux (déroulement de l’annonce du handicap, soutien et aide, information reçue par les parents, afin qu’ils puissent s’adapter positivement à cet événement).
A CRITICAL HEALTH COMMUNICATION PERSPECTIVE ON CURANDERISMO: DECOLONIALITY AND RESISTANCE THROUGH SPIRITUAL HEALING
Creators: name: Tero, Jessica
Publisher: name: Zenodo
Year: 2023
Subjects: curanderismo
spiritual healing
intergenerational trauma
Latinx communication

description: This thesis is a critical qualitative case study that examines the way that curanderismo resists colonial medical practices in the status quo. During this time holistic care is disregarded despite its potential benefits. This can lead to the diminishing of epistemologies, and traditional practices. This study uses a qualitative approach to analyze interviews with four renown practitioners of curanderismo who practice in the Southwestern United States. The analysis focuses on four themes: (1) curanderismo cultural identity (2) curanderismo communication, (3) the three rs of ancestral knowledge, and (4) complementary partnership. The results show how colonial narratives continue to drive people’s perspectives about curanderismo. However, through accounts of practitioners of curanderismo, it opens the door to understand their form of communication and how they hold space for individuals and engage in platica to help people heal. Furthermore, practitioners of curanderismo play an essential role as community members to connect individuals back to their ancestral knowledge allowing for people as a collective engage in healing from historical and intergenerational trauma. Finally, practitioners of curanderismo are open to a complementary partnership with Western medicine in an effort to bring benefits to their communities.
A DNA segment controlling metal-regulated expression of the Drosophila melanogaster metallothionein gene Mtn.
Creators: name: Young, J E
name: Allen, J M
name: Palmiter, R D
name: Maroni, G
name: Otto, E
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Cloned fragments of DNA including the Drosophila melanogaster metallothionein gene Mtn and different amounts of 5' flanking sequences were introduced into flies by P-element-mediated germ line transformation. Comparison of RNA levels in different transformants revealed that metal-regulated and tissue-specific expression of Mtn requires no more than 373 base pairs upstream of the initiation site of transcription. Transformants having an additional, transcribed copy of Mtn could tolerate increased concentrations of cadmium, indicating that Mtn expression is directly related to this phenotype. In separate experiments, these D. melanogaster promoter sequences were fused to the coding sequences of the herpes simplex virus thymidine kinase (TK) gene. After transfection of this fusion into baby hamster kidney cells, increases in TK activity and accumulation of TK RNA were inducible by metals. A series of 5' and 3' deletions showed that D. melanogaster sequences from -130 to -6 were sufficient to confer metal-regulated expression to the TK gene. The function of the D. melanogaster metallothionein promoter in mammalian cells indicates that the mechanism controlling metal regulation is evolutionarily conserved.
Expression and characterization of transforming growth factor alpha precursor protein in transfected mammalian cells.
Creators: name: Lee, D C
name: Twardzik, D R
name: Ranchalis, J E
name: Lim, G J
name: Gentry, L E
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Analysis of a cDNA clone derived from retrovirus-transformed rat fibroblasts has recently suggested that the mature 50-amino-acid form of transforming growth factor alpha (TGF alpha) is derived from a 159-amino-acid transmembrane precursor by proteolytic cleavage. To understand the processing of the TGF alpha precursor molecule in more detail, we have expressed this protein in baby hamster kidney (BHK) fibroblasts under control of the metal-ion-inducible metallothionein promoter and characterized the expressed precursor with site-specific antipeptide antibodies. One of the BHK transfectants, termed 5:2, expressed the TGF alpha mRNA in a cadmium- and zinc-inducible manner. The TGF alpha precursor protein was detected by immunoprecipitation analysis of radiolabeled cell cultures. In the induced 5:2 cells, a polypeptide of Mr 13,000 to 17,000 was readily identified by peptide antisera made to three different regions of the TGF alpha precursor protein. No such protein species were observed in BHK cells treated with cadmium and zinc or in uninduced 5:2 cells. However, two cell lines known to produce TGF alpha naturally, Leydig testicular tumor cells and Snyder-Theilan feline sarcoma virus-transformed Fisher rat embryo fibroblasts, possessed detectable levels of immunologically related Mr 13,000 to 17,000 proteins. Cell fractionation studies indicate that the Mr 13,000 to 17,000 species expressed in induced 5:2 cells is membrane associated, consistent with predictions based on the cDNA sequence of the TGF alpha precursor. Media conditioned by induced 5:2 cells contained epidermal growth factor receptor-competing activity, which, upon size fractionation, was similar in size to the mature processed form of TGF alpha. These data show that these nontransformed BHK cells possess the ability to process the TGF alpha precursor molecule into its native form.
Genetic manipulation of centromere function.
Creators: name: Bloom, K
name: Hill, A
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: A conditional centromere was constructed in Saccharomyces cerevisiae by placing the centromere of chromosome III immediately downstream from the inducible GAL1 promoter from S. cerevisiae. By utilizing growth conditions that favor either transcriptional induction (galactose-carbon source) or repression (glucose-carbon source) from the GAL1 promoter, centromere function can be switched off or on, respectively. With the conditional centromere we were able to radically alter the mitotic transmission pattern of both monocentric and dicentric plasmids. Moreover, it was possible to selectively induce the loss of a single chromosome from a mitotically dividing population of cells. We observed that the induction of chromosome III aneuploidy resulted in a dramatic change in cell morphology. The construction of a conditional centromere represents a novel way to create conditional mutations of cis-acting DNA elements and will be useful for further analysis of this important stabilizing element.
Succinct Permutation Graphs
Creators: name: Tsakalidis, Konstantinos
name: Wild, Sebastian
name: Zamaraev, Viktor
Publisher: name: arXiv
Year: 2020
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences

description: We present a succinct data structure for permutation graphs, and their superclass of circular permutation graphs, i.e., data structures using optimal space up to lower order terms. Unlike concurrent work on circle graphs (Acan et al. 2022), our data structure also supports distance and shortest-path queries, as well as adjacency and neighborhood queries, all in optimal time. We present in particular the first succinct exact distance oracle for (circular) permutation graphs. A second succinct data structure also supports degree queries in time independent of the neighborhood's size at the expense of an $O(\log n/\log \log n)$-factor overhead in all running times. Furthermore, we develop a succinct data structure for the class of bipartite permutation graphs. We demonstrate how to run algorithms directly over our succinct representations for several problems on permutation graphs: Clique, Coloring, Independent Set, Hamiltonian Cycle, All-Pair Shortest Paths, and others. Finally, we initiate the study of semi-distributed graph representations; a concept that smoothly interpolates between distributed (labeling schemes) and centralized (standard data structures). We show how to turn some of our data structures into semi-distributed representations by storing only $O(n)$ bits of additional global information, circumventing the lower bound on distance labeling schemes for permutation graphs.
description: updated to match final Algorithmica version
Ty1 sequence with enhancer and mating-type-dependent regulatory activities.
Creators: name: Errede, B
name: Hutchison, C A
name: Company, M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Some insertion mutations in Saccharomyces cerevisiae activate the expression of adjacent structural genes. The CYC7-H2 mutation is a Ty1 insertion 5' to the iso-2-cytochrome c coding region of CYC7. The Ty1 insertion causes a 20-fold increase in CYC7 expression in a and alpha haploid cell types of S. cerevisiae. This activation is repressed in the a/alpha diploid cell type. Previous computer analysis of the CYC7-H2 Ty1 activator region identified two related sequences with homology both to mammalian enhancers and to a yeast a/alpha control site. A 112-base-pair (bp) DNA fragment encompassing one of these blocks of homology functioned as one component of the Ty1 activator. A 28-bp synthetic oligonucleotide with the wild-type homology block sequence was also functional. A single base pair mutation within the enhancer core of the synthetic 28-bp regulatory element reduced its activation ability to near background amounts. In addition, the 112-bp Ty1 fragment by itself functioned as a target for repression of adjacent gene expression in a/alpha diploid cells.