cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: 'Best Interests' Decision-Making and the Role of the Court in Protecting Patients with Prolonged Disorders of Consciousness
Creators: name: Tanner, Adam
Publisher: name: The Open University
Year: 2022

description: The current law and practice surrounding decision-making for adult patients who lack capacity, because they are in a prolonged disorder of consciousness, leaves these vulnerable patients without adequate protections to ensure their voices are heard. The Mental Capacity Act 2005 and subsequent case law have established that the test to be applied in such cases is whether the decision being made is in the "best interests” of the patient. This thesis looks at how the legal test of best interests is understood and how it is used in practice by doctors and lawyers. It argues that there is a critical misunderstanding of what is meant by best interests, and as a result, vulnerable patients are not having their rights protected. The main thrust of this thesis stems from empirical research into how decisions are made in practice by both clinicians and lawyers; this research takes the form of a series of interviews with leading practitioners and a number of observations of Court of Protection hearings to see first-hand whether decision-makers are following the established law. The empirical work highlights the levels of misunderstanding and poor application of the best interests standard. The interviews identified that the proportion of professionals who do not have an adequate understanding of the law relating to decision-making is perhaps even worse than has been stated in some previous pieces of research. The observations of the Court of Protection indicate that there is a wide discrepancy between what professionals say they do and what they actually do. These observations also uncovered several problems in the current system such as the length of delays and the weight given to expert evidence. This thesis concludes that the law is ultimately misunderstood and incorrectly applied on a routine basis by people whose job is to protect vulnerable parties. The recent developments in the law, by the Supreme Court, potentially go against the foundations of why the Mental Capacity Act 2005 was introduced. There is further consideration as to what future reforms are needed to ensure a patient-centred decision-making framework.
Digitalis - Molecule of the Month September 1996 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for September 1996 about digitalis. It is a pdf archive version of the HTML webpage.
title: Virucidal and Synergistic Activity of Polyphenol-Rich Extracts of Seaweeds against Measles Virus
Creators: name: Morán-Santibañez, Karla
name: Peña-Hernández, Mario A.
name: Cruz-Suárez, Lucia Elizabeth
name: Ricque-Marie, Denis
name: Skouta, Rachid
name: Vasquez, Abimael H.
name: Rodríguez-Padilla, Cristina
name: Trejo-Avila, Laura M.
Publisher: name: University of Massachusetts Amherst
Year: 2018
Subjects: subject: virucidal
subject: Polyphenol-rich extracts
subject: Measles

description: Although preventable by vaccination, Measles still causes thousands of deaths among young children worldwide. The discovery of new antivirals is a good approach to control new outbreaks that cause such death. In this study, we tested the antiviral activity against Measles virus (MeV) of Polyphenol-rich extracts (PPs) coming from five seaweeds collected and cultivated in Mexico. An MTT assay was performed to determine cytotoxicity effect, and antiviral activity was measured by syncytia reduction assay and confirmed by qPCR. PPs from Ecklonia arborea (formerly Eisenia arborea, Phaeophyceae) and Solieria filiformis (Rhodophyta) showed the highest Selectivity Index (SI), >3750 and >576.9 respectively. Both PPs extracts were selected to the subsequent experiments owing to their high efficacy and low cytotoxicity compared with ribavirin (SI of 11.57). The combinational effect of PPs with sulphated polysaccharides (SPs) and ribavirin were calculated by using Compusyn software. Synergistic activity was observed by combining both PPs with low concentrations of Solieria filiformis SPs (0.01 µg/mL). The antiviral activity of the best combinations was confirmed by qPCR. Virucidal assay, time of addition, and viral penetration evaluations suggested that PPs act mainly by inactivating the viral particle. To our knowledge, this is the first report of the virucidal effect of Polyphenol-rich extracts of seaweeds.
Diamond - Molecule of the Month July 1996 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for July 1996 about diamond. It is a pdf archive version of the HTML webpage.
Additional file 1 of Differential expression of coagulation pathway-related proteins in diabetic urine exosomes
Creators: name: Liu, Tianci
name: Liu, Na
name: Wang, Yizhao
name: Li, Tao
name: Zhang, Man
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1: Representative NTA results of urine exosomes.
title: ‘Falling heads’ : investigating reflexive responses to head-neck perturbations
Creators: name: Wochner, Isabell
name: Nölle, Lennart V.
name: Martynenko, Oleksandr V.
name: Schmitt, Syn
Publisher: name: Universität Stuttgart
Year: 2022
Subjects: subject: 570

description: Background: Reflexive responses to head-neck perturbations affect the injury risk in many different situations ranging from sports-related impact to car accident scenarios. Although several experiments have been conducted to investigate these head-neck responses to various perturbations, it is still unclear why and how individuals react differently and what the implications of these different responses across subjects on the potential injuries might be. Therefore, we see a need for both experimental data and biophysically valid computational Human Body Models with bio-inspired muscle control strategies to understand individual reflex responses better.
Methods: To address this issue, we conducted perturbation experiments of the head-neck complex and used this data to examine control strategies in a simulation model. In the experiments, which we call ’falling heads’ experiments, volunteers were placed in a supine and a prone position on a table with an additional trapdoor supporting the head. This trapdoor was suddenly released, leading to a free-fall movement of the head until reflexive responses of muscles stopped the downwards movement.
Results: We analysed the kinematic, neuronal and dynamic responses for all individuals and show their differences for separate age and sex groups. We show that these results can be used to validate two simple reflex controllers which are able to predict human biophysical movement and modulate the response necessary to represent a large variability of participants.
Conclusions: We present characteristic parameters such as joint stiffness, peak accelerations and latency times. Based on this data, we show that there is a large difference in the individual reflexive responses between participants. Furthermore, we show that the perturbation direction (supine vs. prone) significantly influences the measured kinematic quantities. Finally, ’falling heads’ experiments data are provided open-source to be used as a benchmark test to compare different muscle control strategies and to validate existing active Human Body Models directly.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2020
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

286 pages (version 12.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).Version 9.0 released 16 March 2019 (new entry).Version 10.0 released 7 April 2019 (new entry; minor update to previous entry).Version 11 released 31 March 2020 (two new entries; minor update to previous entry).Version 12 released 4 April 2020 (new entry; various minor updates to earlier entries, including updated link, corrected date, corrected name, etc.)
Base de conhecimento de professores de matemática: do genérico ao especializado
Creators: name: Jeferson Gomes Moriel Junior
name: Wielewski, Gladys Denise
Publisher: name: figshare
Year: 2017
Subjects: Education

description: p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 9.0px 'Times New Roman'; color: #1a1919} Several researchers are based on the premise that there is a knowledge basis necessary to teaching to validate a corpus of knowledge mobilized in the Teacher’s practice, aiming at their incorporation into Teacher’s preparation courses, giving rise to di erent models to describe such set of knowledge. However, the most widespread models in the literature are generic and do not relate to a particular discipline, such as Physics, Biology, Geography or Mathematics. This article aims to discuss the current state of development of theoretical perspectives on the knowledge necessary for a mathematics Teacherr. To do so, an analytical-interpretative study was performed of three theoretical models, starting from the generic and culminating in the specialized, that are: the typology of Lee Shulman, the Mathematical Knowledge for Teaching and the Mathematics Teacher’s Specialized Knwledge. The results indicate that Mathematics Teacher’s Specialized Knwledge - its two domains, its six subdomains and nuclear beliefs - is the theoretical model that responds in greater depth, clarity and internal consistency the question: what is the set of specialized knowledge that is necessary to develop a mathematics Teacher? This theoretical model reinforces that being a mathematics Teacher requires the construction of a range of knowledge that is highly specialized, which in turn implies an equally specialized training, in the valuation of the profession and in the creation / maintenance of adequate conditions of preparation and work.
Ship-based measurements of ice nuclei concentrations over the Arctic, Atlantic, Pacific and Southern oceans
Creators: name: Welti, André
name: Bigg, Keith E.
name: DeMott, Paul J.
name: Gong, Xianda
name: Hartmann, Markus
name: Harvey, Mike
name: Henning, Silvia
name: Herenz, Paul
name: Hill, Thomas C.J.
name: Hornblow, Blake
name: Leck, Caroline
name: Löffler, Mareike
name: McCluskey, Christina S.
name: Rauker, Anne Marie
name: Schmale, Julia
name: Tatzelt, Christian
name: Van Pinxteren, Manuela
name: Stratmann, Frank
Publisher: name: Katlenburg-Lindau : EGU
Year: 2020
Subjects: subject: comparative study
subject: concentration (composition)
subject: ice crystal
subject: research vessel
subject: sea ice
subject: shipborne measurement
subject: spatial distribution
subject: spatial variation
subject: Antarctica
subject: Arctic Ocean
subject: Southern Ocean
subject: 550

description: Ambient concentrations of ice-forming particles measured during ship expeditions are collected and summarised with the aim of determining the spatial distribution and variability in ice nuclei in oceanic regions. The presented data from literature and previously unpublished data from over 23 months of ship-based measurements stretch from the Arctic to the Southern Ocean and include a circumnavigation of Antarctica. In comparison to continental observations, ship-based measurements of ambient ice nuclei show 1 to 2 orders of magnitude lower mean concentrations. To quantify the geographical variability in oceanic areas, the concentration range of potential ice nuclei in different climate zones is analysed by meridionally dividing the expedition tracks into tropical, temperate and polar climate zones. We find that concentrations of ice nuclei in these meridional zones follow temperature spectra with similar slopes but vary in absolute concentration. Typically, the frequency with which specific concentrations of ice nuclei are observed at a certain temperature follows a log-normal distribution. A consequence of the log-normal distribution is that the mean concentration is higher than the most frequently measured concentration. Finally, the potential contribution of ship exhaust to the measured ice nuclei concentration on board research vessels is analysed as function of temperature. We find a sharp onset of the influence at approximately 36 C but none at warmer temperatures that could bias ship-based measurements. © Author(s) 2020. This work is distributed under the Creative Commons Attribution 4.0 License.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2020
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

289 pages (version 12.1).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).Version 9.0 released 16 March 2019 (new entry).Version 10.0 released 7 April 2019 (new entry; minor update to previous entry).Version 11.0 released 31 March 2020 (two new entries; minor update to previous entry).Version 12.0 released 4 April 2020 (new entry; various minor updates to earlier entries, including updated link, corrected date, corrected name, etc.)Version 12.1 released 5 April 2020 (excerpts from hoaxed paper replaced with full PDF)
Supplementary Material for: Histamine Iontophoresis as in vivo Model to Study Human Skin Inflammation with Minimal Barrier Impairment: Pilot Study Results of Application of the Model to a Sensitive Skin Panel
Creators: name: Falcone, D.
name: Uzunbajakava, N.
name: Richters, R.
name: P.C.M., Van De Kerkhof
name: P.E.J., Van Erp
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background/Aims: Histamine iontophoresis is known to elicit itch and a wheal-and-flare reaction; however, its impact on the skin barrier and underlying compartments has not been thoroughly evaluated yet. The primary objective of this study was to characterize that using immunohistochemistry, biophysical measurements, and image analysis, and secondly, to explore whether skin reactions to this model differ in sensitive skin (SS). Methods: Eighteen healthy subjects, n = 9 with SS and n = 9 with non-sensitive skin (NSS), were included based on a perception-based questionnaire. Histamine iontophoresis was performed on the buttock, and skin reactions were evaluated up to 72 h after stimulation. Results: The wheal-and-flare peaked at 30 min; after 8 h, no clinical signs were visible. No signs of disruption of the stratum corneum, as well as no increase in the number of Ki67-positive cells emerged, whereas fewer tryptase-positive mast cells and increased epidermal thickness were observed at 1 and 72 h, respectively. SS subjects showed higher perception of itch compared to NSS subjects. Conclusion: Histamine iontophoresis is a well-standardized in vivo model to quantitatively study the early stages of cutaneous inflammation with minimal impact on the skin barrier. In line with previous studies, it highlighted increased sensory perceptions in SS.
Semiparametric Inference for the Functional Cox Model
Creators: name: Hao, Meiling
name: Liu, Kin-yat
name: Xu, Wei
name: Zhao, Xingqiu
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: This article studies penalized semiparametric maximum partial likelihood estimation and hypothesis testing for the functional Cox model in analyzing right-censored data with both functional and scalar predictors. Deriving the asymptotic joint distribution of finite-dimensional and infinite-dimensional estimators is a very challenging theoretical problem due to the complexity of semiparametric models. For the problem, we construct the Sobolev space equipped with a special inner product and discover a new joint Bahadur representation of estimators of the unknown slope function and coefficients. Using this key tool, we establish the asymptotic joint normality of the proposed estimators and the weak convergence of the estimated slope function, and then construct local and global confidence intervals for an unknown slope function. Furthermore, we study a penalized partial likelihood ratio test, show that the test statistic enjoys the Wilks phenomenon, and also verify the optimality of the test. The theoretical results are examined through simulation studies, and a right-censored data example from the Improving Care of Acute Lung Injury Patients study is provided for illustration.
Aspirin - Molecule of the Month February 1996 [Archived version]
Creators: name: May, Paul
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for February 1996 about aspirin. It is a pdf archive version of the HTML webpage.
App-study protocol - supplementary material for RCT
Creators: name: Svendsen, Mathias Tiedemann
name: Andersen, Kirsten Hammond
name: Andersen, Flemming
name: Andersen, Klaus Ejner
Publisher: name: figshare
Year: 2017
Subjects: subject: 110304 Dermatology
subject: FOS: Clinical medicine
subject: Health Care
subject: 111711 Health Information Systems (incl. Surveillance)
subject: FOS: Health sciences

description: Supplementary material for the study protocol"A Designed Patient-Centered Intervention to Improve Medical Adherence in Topical Treatment of Psoriasis: A single-blind randomized controlled trial"Additional file 1: Filled SPIRIT 2013 checklist.Additional file 2: Danish version of advertisement materialAdditional file 3: Licenses to use the copyright instruments Bluetooth, DLQI, and LS-PGAAdditional file 4: Danish version of the informed consent form and the information statement for participantsAdditional file 5: Danish version of information about the technical solutions, study medication, and diary provided to participants in intervention and non-intervention group
Berlin’s Japanese foodscapes during the COVID-19 crisis
Creators: name: Reiher, Cornelia
Publisher: name: Humboldt-Universität zu Berlin
Year: 2022
Subjects: subject: Japanese food
subject: Berlin
subject: COVID-19
subject: restaurateurs
subject: Japanese restaurants
subject: 300 Sozialwissenschaften
subject: 301 Soziologie und Anthropologie

description: The spring 2020 restaurant shutdown after the outbreak of COVID-19 in Berlin hit Japanese restaurateurs at the height of the popularity of Japanese cuisine in Germany. This paper explores how Japanese restaurateurs in Berlin experienced this shutdown from March to May 2020. Based on fieldwork in Berlin, it asks whether and how they continued selling food during the shutdown, compares their experiences and points out similarities and differences that are based on the type of eateries, the restaurateurs’ personal migration histories and the degree of their local embeddedness in Berlin. I pay particular attention to strategies of selling and marketing food during the restaurant shutdown via takeout and delivery services and discuss the material culture of protecting customers and staff from COVID-19 during and after the lockdown against the backdrop of Japanese restaurateurs’ perceptions of health risks. The paper focusses on ethnic Japanese restaurateurs because most of their restaurants are small, independent establishments, and the majority was closed during the shutdown. Although all research participants belong to the same ethnic community, their experiences during and after the shutdown were quite diverse. I argue that their experiences and strategies were influenced by economic factors related to the type of restaurant they run rather than by their ethnicity.
La courante pour clavecin du temps de Chambonnières
Creators: name: Aubin, Nicolas
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2023

description: Le sujet de ce memoire part d'un constat que le claveciniste ne peut manquer de faire au contact du repertoire de la premiere partie du xvne frarn;:ais. 11 s'agit de la profusion de courantes au sein d'une meme suite de danses. Cette etude tente d'en mettre en lumiere les raisons. D'abord, a travers une contextualisation et un historique de son ecriture pour le clavecin, nous tentons de comprendre comment la courante a gagne en complexite jusqu'a changer de mesure, affectee par le rythme de l'hemiole. Puis, nous etudions le concept de suite pour affirmer l'independance de la courante a son egard, et analysons plusieurs courantes de Chambonnieres pour en decrire les caracteres.
APEX Holography Report III
Creators: name: Sridharan Tirupati Kumara
name: Albert Greve
name: Dave Morris
name: Peter Schilke
name: Andreas Lundgren
name: Vincent Reveret
name: Per Bergman
Publisher: name: Zenodo
Year: 2005
Subjects: radio holography
microwave holography
near-field holography
millimeter wave holography
sub-mm antennas
THz antennas

description: The purpose of this document is to describe the holography measurements performed at APEX in April 2005, and to describe the final state of the primary reflector surface. The surface was set to an rms value of 14-15 μm. Maps taken under stable night-time conditions are repeatable to 5.5 μm rms - implying a measurement error of ~ 4 μm rms -  showing the excellent stability of the near-field measurement system / antenna test range. Day-night performance was investigated, and thermal effects at daytime and during transition periods are found. The effect of the temperature control system in the Cassegrain cabin on maintaining the surface accuracy was studied. The standard maps deliver a 12 cm lateral resolution. The surface error in the annular middle 3-m (in radius) is  ~ 13 μm. Repeatable residual error patterns present point to possibilities for further modest improvements.
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2020
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

306 pages (version 13.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).Version 9.0 released 16 March 2019 (new entry).Version 10.0 released 7 April 2019 (new entry; minor update to previous entry).Version 11.0 released 31 March 2020 (two new entries; minor update to previous entry).Version 12.0 released 4 April 2020 (new entry; various minor updates to earlier entries, including updated link, corrected date, corrected name, etc.)Version 12.1 released 5 April 2020 (excerpts from hoaxed paper replaced with full PDF)Version 13.0 released 1 June 2020 (two new entries)
title: The European Union’s Participation in the Creation of Customary International Law and Its Impact on Member State Sovereignty
Creators: name: Binder, Christina
name: Janig, Philipp
Publisher: name: European Papers (www.europeanpapers.eu)
Year: 2024
Subjects: subject: customary law
subject: international organizations
subject: sovereignty
subject: legislative practice
subject: judicial practice
subject: statements in proceedings

description: European Papers - A Journal on Law and Integration, 2023 8(3), 1645-1661
description: I. Introduction. – II. Law-making capacity as an expression of sovereignty. – III. The participation of international organizations in the formation of customary international law. – III.1. Overview. – III.2. Whose practice? – III.3. Which norms? – III.4. Conclusion. – IV. The practice of the EU and its relevance in the creation of customary international law. – IV.1. Overview. – IV.2. Legislative practice of the Union. – IV.3. Judicial practice of the CJEU. – IV.4. Positions taken by the Commission in (quasi-)judicial proceedings. – V. Conclusions.
description: This Article argues that the ability of the European Union to participate in the creation of customary international law curtails the sovereignty of its Member States. First, it shows that authority to participate in norm-creation constitutes a core aspect of sovereignty under international law. Second, it argues that the conduct of the European Union (as an international organization) may be determinative in ascertaining the existence and content of customary norms. However, that authority lacks an explicit basis in the treaties. Third, it asserts that this encompasses norms that are directly relevant for the Member States, potentially in circumstances outside of the scope of EU law. The Article then specifically discusses three types of acts of the Union and their relevance for the creation of customary international law, while providing examples that touch upon traditional inter-states relations. In particular, this concerns the legislative practice of the Union, the judicial practice of the Court of Justice of the European Union (CJEU) and public statements made by the Commission in (quasi-)judicial proceedings.
Improvising 5-HT7R homology model for design of high affinity ligands: model validation with docking, embrace minimization, MM-GBSA, and molecular dynamic simulations
Creators: name: Jha, Preeti
name: Chaturvedi, Shubhra
name: Swastika
name: Pal, Sunil
name: Jain, Nidhi
name: Mishra, Anil K.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The subtype, 5-HT7R has been implicated in neurological disorders and presents itself as a promising target for antidepressant drugs. Design of targeted selective ligands, require a sound knowledge of 3D-receptor structure. In absence of receptor structure, structure-based design of targeted ligands relies on generation of 5-HT7R homology model. In this study, the impact of template choice, alignment, and model building methods on the homology model of 5-HT7R is addressed. The compactness and model quality due to the presence of cholesterol (lipidic receptor) have also been observed. The results suggest good stereochemical quality of the final model. Ramachandran Plot Analysis indicated more than 97.5% amino acid residues in the favorable region. The overall quality factor was 91.8% using ERRAT. The Z-score for backbone confirmation and packing quality were −1.248 and −1.427, respectively, using WHATCHECK. The RMS Z-score for side chain planarity was .711. Other validation results for the final model include binding site analysis in which Asp162, Val163, Phe343, Phe344, Arg350, Arg367, and Leu370 conserved residues were found in the active site, correlation coefficient of .82 in ligand-based screening and .85 in embrace minimization. Further, the model showed good correlation for agonist and antagonist in docking ( ≈ .76, ≈ .82), embrace minimization ( ≈ .73, ≈ .72), and MM-GBSA ( ≈ .69, ≈ .75) studies. The model was subjected to Molecular Dynamics (MD) simulation of 20 ns both in ligand-free and ligand-bound receptor (agonist and antagonist) system in order to assess its stability.
Pierre-Joseph Roussiers Traité des Accords et de leur Succession selon le système de la Basse-Fondamentale. Zum Akkordbegriff in der Rezeption von Jean-Philippe Rameau
Creators: name: Domine, Iris
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2023

description: Wie entwickelte sich der Akkordbegriff in der direkten Rezeption Jean-Philippe Rameaus? Dies untersucht diese Arbeit am Beispiel des 1764 erschienenen Traité des Accords von Pierre-Joseph Roussier. Das musiktheoretische Werk Pierre-Joseph Roussiers (1716-1792) ist bis heute wenig erforscht und rezipiert, insbesondere im deutschsprachigen Raum ist er ein kaum be-kannter Autor. Dabei handelt es sich um einen Autor, der die Ideen seines berühmten Kollegen Jean-Philippe Rameau in seinem eigenen musiktheoretischen Abhandlungen nicht nur explizit aufgriff, sondern auch weiterentwickelte, und der zugleich in den leb-haften Diskussionen und der Musikforschung seiner Zeit mit den Enzyklopädisten eine wichtige Rolle spielte, wie ein an ihn gerichteter Brief von Jean-Jacques Rousseau be-legt. Sein Hauptwerk, der 1764 mehrfach aufgelegte Traité des Accords et de leur Succession selon le Système de la Basse-Fondamentale, bietet einerseits eine kompakte Übersicht und Zusammenfassung des musiktheoretischen Systems des späten Rameaus, die auch einen Ansatz der didaktischen Vereinfachung zeigt; andererseits weist er mit der Vor-stellung nouveaux accords (neuer Akkorde) im letzten Abschnitt, die auch an die Ak-kordlehre von Georg Andreas Sorge erinnern, einen zukunftsweisenden Blick auf.
La douce descordance. Présentation, analyse et transcription de quatre descorts en langue d’oïl (XIIIe s.)
Creators: name: Dupouët, Emmanuel
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2023

description: Le desccort est un genre musical qui fait partie de la lyrique vernaculaire médiévale. Apparu sans doute au début du XIIIe, il a rencontré un certain succès auprès des trou-vères. Ses mélodies complexes et ses très longs poèmes ont suscité l’intérêt des cher-cheurs, mais les neuf chansons en langue d’oïl n’ont pas été éditées en un volume spéci-fique depuis le XIXe siècle. Cet ouvrage tentera d’abord de brosser un portrait du genre, avant de proposer une édition critique de quatre parmi les neuf pièces en oïl qui nous soient parvenues.
Le démanché et le portamento dans les méthodes pour Violoncelle
Creators: name: Egidi, Martin
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2022

description: Ce travail porte sur le concept de démanché dans les méthodes pour violoncelle. Un panorama des différents doigtés en vigueur, du 18ème à la 1ère moitié du 20ème siècle nous permet de comprendre mieux les enjeux concernant les positions et surtout les changements entre elles. Nous étudions ainsi l’intérêt que portent les auteurs au démanché ainsi que certains compositeurs. Parallèlement au développement du démanché comme enjeu crucial de la technique de main gauche, le portamento apparaît et nous relevons ainsi toutes les mentions de cet outil expressif dans les traités consacrés au violoncelle ainsi que plusieurs exemples tirés du répertoire. Nous terminons le travail par une étude de cas d’une pièce de R. Schumann et comparons différentes éditions avec leurs doigtés et plusieurs enregistrements historiques de la première moitié du 20ème siècle afin d’obtenir quelques considérations plus pratiques sur ces sujets.
App-study protocol - supplementary material for RCT
Creators: name: Svendsen, Mathias Tiedemann
name: Andersen, Kirsten Hammond
name: Andersen, Flemming
name: Andersen, Klaus Ejner
Publisher: name: figshare
Year: 2017
Subjects: subject: 110304 Dermatology
subject: FOS: Clinical medicine
subject: Health Care
subject: 111711 Health Information Systems (incl. Surveillance)
subject: FOS: Health sciences

description: Supplementary material for the study protocol"A Designed Patient-Centered Intervention to Improve Medical Adherence in Topical Treatment of Psoriasis: A single-blind randomized controlled trial"Additional file 1: Filled SPIRIT 2013 checklist.Additional file 2: Danish version of advertisement materialAdditional file 3: Licenses to use the copyright instruments Bluetooth, DLQI, and LS-PGAAdditional file 4: Danish version of the informed consent form and the information statement for participantsAdditional file 5: Danish version of information about the technical solutions, study medication, and diary provided to participants in intervention and non-intervention GroupAdditional file 6: General information. Name and addresses of study site, affiliated laboratory, business partners, and public authorities providing assistance for the studyAdditional file 7: Guidelines for publication
Le Variazioni Goldberg. Un’analisi in chiave pedagogica
Creators: name: Gaudio, Cristiano
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2023

description: Il lavoro esamina le possibilità di un approccio pedagogico alle Variazioni Goldberg. Discusse brevemente le fonti dell’opera e il suo contesto, il Capitolo I indaga il termine Clavier-Übung, considerandone il significato etimologico e il suo impiego ai tempi di Johann Sebastian Bach. Il Capitolo II pone in prospettiva storica la prassi strumentale bachiana e la sua pedagogia. Dopo una riflessione sull’uso che si può fare oggi di opere del passato non concepite con una finalità prettamente didattica, il Capitolo III propone un confronto con le esecuzioni odierne e analizza le Goldberg strutturando un percorso di risoluzione pratica dei problemi tecnico-musicali.
À deux violons. Le due suite d’airs d’opéra de L’abbé le fils in una prospettiva pedagogica
Creators: name: Manfredini, Giulia
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2023

description: Le seguenti pagine sono il frutto di un’analisi in chiave storica e pedagogica delle due suite per due violini presenti nel metodo per violino Principes du Violon de L’abbé le fils (1761). La ricerca si propone di presentare il contesto storico e culturale-estetico della Francia di metà Settecento nel quale visse l’autore del metodo e di offrire un pano-rama della didattica violinistica francese del Settecento. Conclude il lavoro una propo-sta pedagogica su una selezione di brani delle due suite, volta a valorizzare in essi i principi estetici e violinistici caratteristici del milieu culturale dal quale provengono.
L’Insegnamento del Flauto Dritto nella Venezia del Primo Settecento. Tra Amatori, Orfane e Professionisti
Creators: name: Massenzana, Cecilia
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2023

description: In una florida Venezia di inizio Settecento, dove l’intensa attività musicale spaziava dal-la musica sacra nelle numerose chiese ed ospedali, alle nuove opere ascoltate in tutti i teatri, dai balli di Carnevale, fino alle musiche da battello nelle sere d’estati e alle feste private delle accademie e delle famiglie patrizie veneziane, l’offerta didattica era molto ampia. In questo scritto vengono analizzati i contratti di garzonaggio che venivano sti-pulati tra i maestri e i futuri musicisti professionisti e viene messo in risalto il ruolo del flauto dolce all’interno dell’attività educativa di degli ospedali. Infine si analizzano le diverse raccolte manoscritte dedicate alla didattica del flauto dritto, ritrovate nelle bi-blioteche delle famiglie nobili veneziane che usavano praticare per diletto la musica su questo strumento.
App-study protocol - supplementary material for RCT
Creators: name: Svendsen, Mathias Tiedemann
name: Andersen, Kirsten Hammond
name: Andersen, Flemming
name: Andersen, Klaus Ejner
Publisher: name: figshare
Year: 2017
Subjects: subject: 110304 Dermatology
subject: FOS: Clinical medicine
subject: Health Care
subject: 111711 Health Information Systems (incl. Surveillance)
subject: FOS: Health sciences

description: Supplementary material for the study protocol"A Designed Patient-Centered Intervention to Improve Medical Adherence in Topical Treatment of Psoriasis: A single-blind randomized controlled trial"Additional file 1: Filled SPIRIT 2013 checklist.Additional file 2: Danish version of advertisement materialAdditional file 3: Licenses to use the copyright instruments Bluetooth, DLQI, and LS-PGAAdditional file 4: Danish version of the informed consent form and the information statement for participantsAdditional file 5: Danish version of information about the technical solutions, study medication, and diary provided to participants in intervention and non-intervention GroupAdditional file 6: General information. Name and addresses of study site, affiliated laboratory, business partners, and public authorities providing assistance for the studyAdditional file 7: Guidelines for publicationAdditional file 8: Screening and reporting of adverse events (AEs)
title: 01_1149
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Stinging the Predators: A collection of papers that should never have been published
Creators: name: Faulkes, Zen
Publisher: name: figshare
Year: 2020
Subjects: Science Policy

description: This ebook collects academic papers and conference abstracts that were meant to be so terrible that nobody in their right mind would publish them. All were submitted to journals and conferences to expose weak or non-existent peer review and other exploitative practices. Each paper has a brief introduction. Short essays round out the collection.

316 pages (version 14.0).

Version 1.0 released 26 July 2017.
Version 2.0 released 28 July 2017 (two new entries).
Version 3.0 released 31 July 2017 (two new entries).
Version 3.1 released 7 August 2017 (error corrected).
Version 4.0 released 16 February 2018 (one new entry).
Version 4.1 released 16 February 2018 (journal PDF replaced copied text).Version 5.0 released 4 July 2018 (one new entry).Version 6.0 released 26 July 2018 (one new entry).Version 6.1 released 28 July 2018 (journal PDF replaced copied text).Version 7.0 released 29 September 2018 (one new entry).Version 8.0 released 3 October 2018 (one new entry with featuring three new papers).Version 8.1 released 4 October 2018 (one new paper added associated with v 8.0 entry; PDF bookmarks fixed).Version 8.2 released 7 October 2018 (expanded introduction associated with v 8.0 entry).Version 8.3 released 30 October 2018 (expanded introduction associated with v 8.0 entry; minor addition to earlier entries).Version 9.0 released 16 March 2019 (new entry).Version 10.0 released 7 April 2019 (new entry; minor update to previous entry).Version 11.0 released 31 March 2020 (two new entries; minor update to previous entry).Version 12.0 released 4 April 2020 (new entry; various minor updates to earlier entries, including updated link, corrected date, corrected name, etc.)Version 12.1 released 5 April 2020 (excerpts from hoaxed paper replaced with full PDF)Version 13.0 released 1 June 2020 (two new entries)Version 14.0 released 15 August 2020 (one new entries)
Supplementary Material for: Autologous Adipose Tissue Graft to Treat Hypertensive Leg Ulcer: A Pilot Study
Creators: name: Chopinaud, M.
name: Labbé, D.
name: Creveuil, C.
name: Marc, M.
name: Bénateau, H.
name: Mourgeon, B.
name: Chopinaud, E.
name: Veyssière, A.
name: Dompmartin, A.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: Adipose tissue is an abundant source of mesenchymal stem cells, called adipose-derived stem cells, which have anti-inflammatory and trophic effects to enhance overall tissue repair. Objective: To determine the healing effects of autologous adipose tissue graft on hypertensive leg ulcers. Methods: Prospective pilot study in 1 French dermatology department. Ten patients with a hypertensive leg ulcer were enrolled from April 2013 to June 2015. The primary end point was the wound closure rate at each follow-up visit. The secondary end points were wound characteristics, pain assessment and adverse events. Results: One patient, the only smoker, was lost to follow-up at month 5 (M5). For the 9 non-smokers, wound surfaces constantly and significantly decreased: the median wound closure rate was 73.2% at M3 and 93.1% at M6, p < 0.001. The median wound closure rate of the 10 patients was 63.2% at M3, p < 0.001. Percentages of fibrin and necrosis decreased, granulation tissue increased significantly. Pain rapidly and significantly decreased. No recurrence or adverse event was observed. Conclusion: Our data suggest that autologous adipose tissue grafting induces pain relief and promotes wound healing with a good skin quality. Large prospective controlled randomized studies are required to confirm these results.
“Chi semina fiori raccoglie bouquets”. Pedagogia violinistica barocca alla Schola Cantorum Basiliensis negli anni 1991 – 2022
Creators: name: Rosato, Lorenzo
Publisher: name: Hochschule für Musik Basel FHNW, Schola Cantorum Basiliensis
Year: 2023

description: Il presente lavoro, basatosi principalmente sull’analisi di alcune interviste condotte personalmente dall’autore con le Prof.sse Chiara Banchini, Leila Schayegh e Amandine Beyer, si propone di indagare le vicende che hanno contraddistinto la pedagogia violini-stica barocca alla Schola Cantorum Basiliensis negli anni 1991 – 2022. Oltre ad infor-mazioni di carattere biografico-storico-nozionistico, è stato possibile ricostruire, con l’aiuto di ulteriore documentazione, alcuni aspetti fondamentali che caratterizzano la SCB come luogo di apprendimento, le differenze tra gli anni presenti e passati, i metodi d’insegnamento utilizzati dalle tre docenti, nonché i possibili sviluppi pedagogici futuri in quest’ambito.