cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Infrared tip-tilt sensing: on-sky experience, lessons learned and unsolved problems
Creators: name: van Dam, Marcos A.
name: Oberti, Sylvain
name: Kolb, Johann
name: Lyke, Jim
name: Cetre, Sylvain
name: Neichel, Benoit
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Infrared tip-tilt sensors (IR TTSs) have been deployed on three different laser guide star adaptive optics (AO) systems on three different telescopes. These IR TTS benefit from the high-order loop PSF sharpening in the near infrared, hence they provide a low tip-tilt residual and a good sky coverage. Nevertheless, these IR TTS are challenging and their use in AO is limited. In this paper, we outline existing IR TTS, provide on-sky performance results and describe our experience using IR TTS and along with plans for the near future. The second part of the paper deals with unresolved challenges for IR TTS. These include algorithms and loop stability in the low Strehl regime, using IR TTSs to measure higher-order modes and guiding on multiple guide stars with different magnitudes.
Big Bang Nucleosynthesis Hunts Chameleon Dark Matter
Creators: name: Chen, Hua
name: Katsuragawa, Taishi
name: Matsuzaki, Shinya
name: Qiu, Taotao
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the chameleon field dark matter, dubbed \textit{scalaron}, in $F(R)$ gravity in the Big Bang Nucleosynthesis (BBN) epoch. With an $R^{2}$-correction term required to solve the singularity problem for $F(R)$ gravity, we first find that the scalaron dynamics is governed by the $R^{2}$ term and the chameleon mechanism in the early universe, which makes the scalaron physics model-independent regarding the low-energy scale modification. In viable $F(R)$ dark energy models including the $R^{2}$ correction, our analysis suggests the scalaron universally evolves in a way with a bouncing oscillation irrespective of the low-energy modification for the late-time cosmic acceleration. Consequently, we find a universal bound on the scalaron mass in the BBN epoch, to be reflected on the constraint for the coupling strength of the $R^2$ term, which turns out to be more stringent than the one coming from the fifth force experiments. It is then shown that the scalaron naturally develops a small enough fluctuation in the BBN epoch, hence can avoid the current BBN constraint placed by the latest Planck 2018 data, and can also have a large enough sensitivity to be hunted by the BBN, with more accurate measurements for light element abundances as well as the baryon number density fraction.
description: 29 pages, 7 figures, Prepared for submission to JHEP
title: Access to Data in Connected Cars and the Recent Reform of the Motor Vehicle Type Approval Regulation
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Kerber, Wolfgang
name: Gill, Daniel
Publisher: name: Philipps-Universität Marburg
Year: 2019
Subjects: Internet of Things
Economics
Wirtschaft
data access
connected cars
digital economy
aftermarkets

description: The need for regulatory solutions for access to in-vehicle data and resources of connected cars is one of the big controversial and unsolved policy issues. Last year the EU revised the Motor Vehicle Type Approval Regulation which already entailed a FRAND-like solution for the access to repair and maintenance information (RMI) to protect competition on the automotive aftermarkets. However, the transition to connected cars changes the technological conditions for this regulatory solution significantly. This paper analyzes the reform of the type approval regulation and shows that the regulatory solutions for access to RMI are so far only very insufficiently capable of dealing with the challenges coming along with increased connectivity, e.g. with regard to the new remote diagnostic, repair and maintenance services. Therefore, an important result of the paper is that the transition to connected cars will require a further reform of the rules for the regulated access to RMI (esp. with regard to data access, interoperability, and safety/security issues). However, our analysis also suggests that the basic approach of the current regulated access regime for RMI in the type approval regulation can also be a model for developing general solutions for the currently unsolved problems of access to in-vehicle data and resources in the ecosystem of connected driving.
title: Drought and property Prices: Empirical Evidence from Iran
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Farzanegan, Mohammad Reza
name: Feizi, Mehdi
name: Fereidouni, Gholipour
Publisher: name: Philipps-Universität Marburg
Year: 2019
Subjects: Property Prices
Iran
Drought
Economics
Wirtschaft
Water Crisis
Housing

description: This study demonstrates an economic consequence of climate change and water crises in Iran. It examines the effect of drought on housing prices, residential land prices, and housing rents in Iran. Using data from provinces of Iran from 1993 to 2015 and applying static and dynamic panel fixed effects estimators, we find evidence that an increase in the balance of water (reducing the severity of drought) within provinces has a positive effect on property prices. Our results have important implications for Iranian policymakers and property investors.
Reflection Amplitudes of Boundary Toda Theories and Thermodynamic Bethe Ansatz
Creators: name: Ahn, Changrim
name: Kim, Chanju
name: Rim, Chaiho
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the ultraviolet asymptotics in $A_n$ affine Toda theories with integrable boundary actions. The reflection amplitudes of non-affine Toda theories in the presence of conformal boundary actions have been obtained from the quantum mechanical reflections of the wave functional in the Weyl chamber and used for the quantization conditions and ground-state energies. We compare these results with the thermodynamic Bethe ansatz derived from both the bulk and (conjectured) boundary scattering amplitudes. The two independent approaches match very well and provide the non-perturbative checks of the boundary scattering amplitudes for Neumann and $(+)$ boundary conditions. Our results also confirm the conjectured boundary vacuum energies and the duality conjecture between the two boundary conditions.
description: 20 pages, 3 figures, LaTeX2e
An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study
Creators: name: Sourav Das
name: Sharat Sarmah
name: Lyndem, Sona
name: Atanu Singha Roy
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: A new strain of a novel infectious disease affecting millions of people, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently been declared as a pandemic by the World Health Organization (WHO). Currently, several clinical trials are underway to identify specific drugs for the treatment of this novel virus. The inhibition of the SARS-CoV-2 main protease is necessary for the blockage of the viral replication. Here, in this study, we have utilized a blind molecular docking approach to identify the possible inhibitors of the SARS-CoV-2 main protease, by screening a total of 33 molecules which includes natural products, anti-virals, anti-fungals, anti-nematodes and anti-protozoals. All the studied molecules could bind to the active site of the SARS-CoV-2 protease (PDB: 6Y84), out of which rutin (a natural compound) has the highest inhibitor efficiency among the 33 molecules studied, followed by ritonavir (control drug), emetine (anti-protozoal), hesperidin (a natural compound), lopinavir (control drug) and indinavir (anti-viral drug). All the molecules, studied out here could bind near the crucial catalytic residues, HIS41 and CYS145 of the main protease, and the molecules were surrounded by other active site residues like MET49, GLY143, HIS163, HIS164, GLU166, PRO168, and GLN189. As this study is based on molecular docking, hence being particular about the results obtained, requires extensive wet-lab experimentation and clinical trials under in vitro as well as in vivo conditions. Communicated by Ramaswamy H. Sarma
Chandra observations of the bursting X-ray transient SAX J1747.0-2853 during low-level accretion activity
Creators: name: Wijnands, Rudy
name: Miller, J. M.
name: Wang, Q. Daniel
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present Chandra/ACIS observations of the bursting X-ray transient SAX J1747.0-2853 performed on 18 July 2001. We detected a bright source at the position of R.A = 17^h 47^m 02.60^s and Dec. = -28 52' 58.9'' (J2000.0; with a 1 sigma error of ~0.7 arcseconds), consistent with the BeppoSAX and ASCA positions of SAX J1747.0-2853 and with the Ariel V position of the transient GX +0.2,-0.2, which was active during the 1970's. The 0.5-10 keV luminosity of the source during our observations was ~3 x 10^{35} erg/s (assuming a distance of 9 kpc) demonstrating that the source was in a low-level accretion state. We also report on the long-term light curve of the source as observed with the all sky monitor aboard the Rossi X-ray Timing Explorer. After the initial 1998 outburst, two more outbursts (in 2000 and 2001) were detected with peak luminosities about two orders of magnitude larger than our Chandra luminosity. Our Chandra observation falls in-between those two outbursts, making the outburst history for SAX J1747.0-2853 complex. Those bright 2000 and 2001 outbursts combined with the likely extended period of low level activity in-between those outbursts strongly suggest that the classification of SAX J1747.0-2853 as a faint X-ray transient was premature. It might be possible that the other faint X-ray transients also can exhibit bright, extended outbursts which would eliminate the need for a separate sub-class of X-ray transients. We discuss our results also in the context of the behavior of X-ray binaries accreting at low levels with luminosities around 10^{35} erg/s, a poorly studied accretion rate regime.
description: Accepte for publication in ApJ, 11 July 2002
Analysis of the interaction behavior between Nano-Curcumin and two human serum proteins: combining spectroscopy and molecular stimulation to understand protein-protein interaction
Creators: name: Mokaberi, Parisa
name: Babayan-Mashhadi, Fatemeh
name: Zadeh, Zeinab Amiri Tehrani
name: Saberi, Mohammad Reza
name: Jamshidkhan Chamani
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: In this study, we have investigated the effects of Nano-curcumin (Nano-CUR) binding on HSA-HTF interactions as binary and ternary systems, which had been done through multiple spectroscopic and MD simulation. It has been indicated by fluorescence spectroscopy that Nano-CUR is capable of quenching both proteins with a static mechanism. Thermodynamic parameters have been calculated by considering the fluorescence data at different temperatures. The binding constants of HSA-Nano-CUR, HTF-Nano-CUR and (HSA-HTF) Nano-CUR complexes formation were (2.03 ± 0.32)×107 M−1, (2.46 ± 0.32)×106 and (4.54 ± 0.32)×106 M−1 respectively. According to the negative values of ΔH0 and ΔS0, the roles of van-der-Waals forces and hydrogen bond are quite essential throughout this particular binding. Besides, the negative ΔH0 and ΔS0 values of HTF (Nano-CUR) have been larger than those of the HSA (Nano-CUR) and HSA-HTF (Nano-CUR), which demonstrates the higher significance of interaction bonding. As it had been detected through the synchronized fluorescence spectroscopy at Δλ = 60 nm, the position of Nano-CUR with mixed protein in ternary system has been closer to Tyr residues. Relatively, the binding distances between Trp residues of HSA and HTF in HSA (Nano-CUR), HTF (Nano-CUR), and (HSA-HTF Nano-CUR) complexes, which had been procured in accordance with the fluorescence resonance energy transfer (FRET), have been found to be 1.82 nm, 1.87 nm, and 1.92 nm, respectively. We have evaluated the induced conformational changes of two proteins throughout the binding of Nano-CUR to HSA and HTF as binary and ternary systems by employing the CD technique, while the formation of self-assemblies has been studied through MD simulation.
Manifold Embedded Knowledge Transfer for Brain-Computer Interfaces
Creators: name: Zhang, Wen
name: Wu, Dongrui
Publisher: name: arXiv
Year: 2019
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Transfer learning makes use of data or knowledge in one problem to help solve a different, yet related, problem. It is particularly useful in brain-computer interfaces (BCIs), for coping with variations among different subjects and/or tasks. This paper considers offline unsupervised cross-subject electroencephalogram (EEG) classification, i.e., we have labeled EEG trials from one or more source subjects, but only unlabeled EEG trials from the target subject. We propose a novel manifold embedded knowledge transfer (MEKT) approach, which first aligns the covariance matrices of the EEG trials in the Riemannian manifold, extracts features in the tangent space, and then performs domain adaptation by minimizing the joint probability distribution shift between the source and the target domains, while preserving their geometric structures. MEKT can cope with one or multiple source domains, and can be computed efficiently. We also propose a domain transferability estimation (DTE) approach to identify the most beneficial source domains, in case there are a large number of source domains. Experiments on four EEG datasets from two different BCI paradigms demonstrated that MEKT outperformed several state-of-the-art transfer learning approaches, and DTE can reduce more than half of the computational cost when the number of source subjects is large, with little sacrifice of classification accuracy.
title: Who Is Successful in Foreign Exchange Margin Trading? New Survey Evidence from Japan
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Hayo, Bernd
name: Iwatsubo
Publisher: name: Philipps-Universität Marburg
Year: 2019
Subjects: investor survey
foreign exchange trading profits
Economics
Wirtschaft
Foreign exchange margin trading
Japan
financial literacy

description: We use a 2018 survey of FX margin traders in Japan to investigate which key factors influence their performance: socio-demographic and economic situation, investment strategy and trading behaviour, and/or financial literacy. First, the data show that variables from all three groups are significant predictors of traders’ performance. Second, we find that older traders and those without a specific trading strategy demonstrate lower performance. Performance is higher for those who trade greater amounts, rely more on fundamental analysis, and report having profitable FX trade skills. Third, respondents’ subjectively stated claim of having FX trade skills is based on a more advanced understanding of FX trading and a reliance on professional advice. Neither objective financial knowledge nor over/underconfidence play a noteworthy role in the performance of margin traders.
Many-body dipole-induced dipole model for electrorheological fluids
Creators: name: Huang, J. P.
name: Yu, K. W.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Theoretical investigations on electrorheological (ER) fluids usually rely on computer simulations. An initial approach for these studies would be the point-dipole (PD) approximation, which is known to err considerably when the particles approach and finally touch due to many-body and multipolar interactions. Thus various work attempted to go beyond the PD model. Being beyond the PD model, previous attempts have been restricted to either local-field effects only or multipolar effects only, but not both. For instance, we recently proposed a dipole-induced-dipole (DID) model which is shown to be both more accurate than the PD model and easy to use. This work is necessary because the many-body (local-field) effect is included to put forth the many-body DID model. The results show that the multipolar interactions can indeed be dominant over the dipole interaction, while the local-field effect may yield an important correction.
description: RevTeX, 3 eps figures
An in-silico evaluation of different Saikosaponins for their potency against SARS-CoV-2 using NSP15 and fusion spike glycoprotein as targets
Creators: name: Saurabh K. Sinha
name: Anshul Shakya
name: Satyendra K. Prasad
name: Shashikant Singh
name: Nilambari S. Gurav
name: Rupali S. Prasad
name: Gurav, Shailendra S.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: The Public Health Emergency of International Concern declared the widespread outbreak of SARS-CoV-2 as a global pandemic emergency, which has resulted in 1,773,086 confirmed cases including 111,652 human deaths, as on 13 April 2020, as reported to World Health Organization. As of now, there are no vaccines or antiviral drugs declared to be officially useful against the infection. Saikosaponin is a group of oleanane derivatives reported in Chinese medicinal plants and are described for their anti-viral, anti-tumor, anti-inflammatory, anticonvulsant, antinephritis and hepatoprotective activities. They have also been known to have anti-coronaviral property by interfering the early stage of viral replication including absorption and penetration of the virus. Thus, the present study was undertaken to screen and evaluate the potency of different Saikosaponins against different sets of SARS-CoV-2 binding protein via computational molecular docking simulations. Docking was carried out on a Glide module of Schrodinger Maestro 2018-1 MM Share Version on NSP15 (PDB ID: 6W01) and Prefusion 2019-nCoV spike glycoprotein (PDB ID: 6VSB) from SARS-CoV-2. From the binding energy and interaction studies, the Saikosaponins U and V showed the best affinity towards both the proteins suggesting them to be future research molecule as they mark the desire interaction with NSP15, which is responsible for replication of RNA and also with 2019-nCoV spike glycoprotein which manage the connection with ACE2.
MOESM3 of Systematic review of the use of process evaluations in knowledge translation research
Creators: name: Scott, Shannon
name: Rotter, Thomas
name: Flynn, Rachel
name: Brooks, Hannah
name: Plesuk, Tabatha
name: Bannar-Martin, Katherine
name: Chambers, Thane
name: Hartling, Lisa
Publisher: name: figshare
Year: 2019
Subjects: Cancer
Science Policy

description: Additional file 3. Citation List of Included Studies. Citation list for studies included in this review.
Shot noise in multi-tracer constraints on $f_\text{NL}$ and relativistic projections: Power Spectrum
Creators: name: Ginzburg, Dimitry
name: Desjacques, Vincent
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Multiple tracers of the same surveyed volume can enhance the signal-to-noise on a measurement of local primordial non-Gaussianity and the relativistic projections. Increasing the number of tracers comparably increases the number of shot noise terms required to describe the stochasticity of the data. Although the shot noise is white on large scales, it is desirable to investigate the extent to which it can degrade constraints on the parameters of interest. In a multi-tracer analysis of the power spectrum, a marginalization over shot noise does not degrade the constraints on $f_\text{NL}$ by more than $\sim 30$% so long as halos of mass $M\lesssim 10^{12}M_\odot$ are resolved. However, ignoring cross shot noise terms induces large systematics on a measurement of $f_\text{NL}$ at redshift $z<1$ when small mass halos are resolved. These effects are less severe for the relativistic projections, especially for the dipole term. In the case of a low and high mass tracer, the optimal sample division maximizes the signal-to-noise on $f_\text{NL}$ and the projection effects simultaneously, reducing the errors to the level of $\sim 10$ consecutive mass bins of equal number density. We also emphasize that the non-Poissonian noise corrections that arise from small-scale clustering effects cannot be measured with random dilutions of the data. Therefore, they must either be properly modeled or marginalized over.
description: 12 pages, 7 figures. Accepted for publication by MNRAS
Asymmetric Hash Code Learning for Remote Sensing Image Retrieval
Creators: name: Song, Weiwei
name: Gao, Zhi
name: Dian, Renwei
name: Ghamisi, Pedram
name: Zhang, Yongjun
name: Benediktsson, Jón Atli
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Remote sensing image retrieval (RSIR), aiming at searching for a set of similar items to a given query image, is a very important task in remote sensing applications. Deep hashing learning as the current mainstream method has achieved satisfactory retrieval performance. On one hand, various deep neural networks are used to extract semantic features of remote sensing images. On the other hand, the hashing techniques are subsequently adopted to map the high-dimensional deep features to the low-dimensional binary codes. This kind of methods attempts to learn one hash function for both the query and database samples in a symmetric way. However, with the number of database samples increasing, it is typically time-consuming to generate the hash codes of large-scale database images. In this paper, we propose a novel deep hashing method, named asymmetric hash code learning (AHCL), for RSIR. The proposed AHCL generates the hash codes of query and database images in an asymmetric way. In more detail, the hash codes of query images are obtained by binarizing the output of the network, while the hash codes of database images are directly learned by solving the designed objective function. In addition, we combine the semantic information of each image and the similarity information of pairs of images as supervised information to train a deep hashing network, which improves the representation ability of deep features and hash codes. The experimental results on three public datasets demonstrate that the proposed method outperforms symmetric methods in terms of retrieval accuracy and efficiency. The source code is available at https://github.com/weiweisong415/Demo AHCL for TGRS2022.
description: 14 pages, 12 figures, and 2 tables
The role of culture in children’s sex-typed preferences for colours, toys, and affordances: A systems theory approach
Creators: name: Davis, Jacqueline Topsy Mengersen
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Culture
Gender
Developmental Psychology
Systems Theory
Behavioural Science
Dynamic Systems
Machine Learning
Complex Systems

description: Children’s sex-typed preferences for colours and toys are well-established, and often function as markers of sex-typicality in research on the development of sex-typed behaviour. However, children’s sex-typed colour and toy preferences have not been tested cross-culturally, or in remote unindustrialised cultural settings. The present thesis tested children’s preferences for sex-typed toys in four cultural settings: Shipibo villages in the Lake Imiria region of the Peruvian Amazon; kastom villages in the mountains of Tanna Island in Vanuatu in the South Pacific; children attending school in Lenakel town on Tanna Island; and in a large industrialised city in Australia. It also tested children’s colour preferences in three of these cultures. It was hypothesised that colour and toy preferences would show some similarities across cultures, and further, that similarities in toy preferences across cultures would be explained by the different types of play afforded by the toys. Results suggested that colour preferences, specifically, a sex difference in preference for pink, are specific to industrialised cultures. Results further suggested that some sex differences in toy preferences replicate in different cultures, and that the relationship between toy preferences and children’s preferences for play affordances is a potentially important area for further research. The present thesis also provided two demonstrations of how new statistical methods, adapted from complex and dynamic systems theory, could be applied to the cross-cultural dataset. A machine learning method suggested that sex, more than culture, affects children’s sex-typed toy preferences. A multistate dynamic method further suggested that sex, more than culture, affects the dynamics of children’s toy choices.
description: PhD funded by Gates Cambridge
Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach
Creators: name: Sukanth Kumar Enmozhi
name: Raja, Kavitha
name: Irudhayasamy Sebastine
name: Jerrine Joseph
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: SARS-CoV-2 virus which caused the global pandemic the Coronavirus Disease- 2019 (COVID-2019) has infected about 1,203,959 patients and brought forth death rate about 64,788 among 206 countries as mentioned by WHO in the month of April 2020. The clinical trials are underway for Remdesivir, an investigational anti-viral drug from Gilead Sciences. Antimalarial drugs such as Chloroquine and Hydroxychloroquine derivatives are being used in emergency cases; however, they are not suitable for patients with conditions like diabetes, hypertension and cardiac issues. The lack of availability of approved treatment for this disease calls forth the scientific community to find novel compounds with the ability to treat it. This paper evaluates the compound Andrographolide from Andrographis paniculata as a potential inhibitor of the main protease of SARS-COV-2 (Mpro) through in silico studies such as molecular docking, target analysis, toxicity prediction and ADME prediction. Andrographolide was docked successfully in the binding site of SARS-CoV-2 Mpro. Computational approaches also predicts this molecule to have good solubility, pharmacodynamics property and target accuracy. This molecule also obeys Lipinski’s rule, which makes it a promising compound to pursue further biochemical and cell based assays to explore its potential for use against COVID-19. Communicated by Ramaswamy H. Sarma
Decoherence in a Cooper pair shuttle
Creators: name: Romito, Alessandro
name: Plastina, Francesco
name: Fazio, Rosario
Publisher: name: arXiv
Year: 2002
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We examine decoherence effects in the Josephson current of a Cooper pair shuttle. Dephasing due to gate voltage fluctuations can either suppress or enhance the critical current and also change its sign. The current noise spectrum displays a peak at the Josephson coupling energy and shows a phase dependence.
description: 11 pages, 5 figures; v3 (published version): major changes, added refernces
Quantum hydrodynamics of a single particle
Creators: name: Suárez-Forero, D. G.
name: Ardizzone, V.
name: da Silva, S. F. Covre
name: Reindl, M.
name: Fieramosca, A.
name: Polimeno, L.
name: de Giorgi, M.
name: Dominici, L.
name: Pfeiffer, L. N.
name: Gigli, G.
name: Ballarini, D.
name: Laussy, F.
name: Rastelli, A.
name: Sanvitto, D.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Applied Physics (physics.app-ph)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Semiconductor devices are strong competitors in the race for the development of quantum com-putational systems. In this work, we interface two semiconductor building blocks of different di-mensionality and with complementary properties: (1) a quantum dot hosting a single exciton andacting as a nearly ideal single-photon emitter and (2) a quantum well in a 2D microcavity sustain-ing polaritons, which are known for their strong interactions and unique hydrodynamics propertiesincluding ultrafast real-time monitoring of their propagation and phase-mapping. In the presentexperiment we can thus observe how the injected single particles propagate and evolve inside themicrocavity, giving rise to hydrodynamics features typical of macroscopic systems despite their in-trinsic genuine quantum nature. In the presence of a structural defect, we observe the celebratedquantum interference of a single particle that produces fringes reminiscent of a wave propagation.While this behaviour could be theoretically expected, our imaging of such an interference pattern,together with a measurement of antibunching, constitutes the first demonstration of spatial mappingof the self-interference of a single quantum particle hitting an obstacle.
description: 9 pages, 4 figures, supplementary 4 pages, 6 figures
Reformulation of Smoothed Particle Hydrodynamics with Riemann Solver
Creators: name: Inutsuka, Shu-ichiro
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Smoothed Particle Hydrodynamics is reformulated in terms of the convolution of the original hydrodynamics equations, and the new evolution equations for the particles are derived. The same evolution equation of motion is also derived using a new action principle. The force acting on each particle is determined by solving the Riemann problem. The use of the Riemann Solver strengthens the method, making it accurate for the study of phenomena with strong shocks. The prescription for the variable smoothing length is shown. These techniques are implemented in strict conservation form. The results of a few test problems are also shown.
description: 30 pages, 13 figures
title: Revenue decoupling and energy consumption: Empirical evidence from the U.S. electric utilities sector
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: von Loessl, Victor
name: Wetzel, Heike
Publisher: name: Philipps-Universität Marburg
Year: 2019
Subjects: demand frontier function
energy efficiency
transient and persistent efficiency
Revenue decoupling
Economics
Wirtschaft
stochastic frontier analysis

description: Energy efficiency provides a substantial opportunity to tackle increasing greenhouse gas emissions. However, in traditionally regulated energy markets, energy providers maximize their profits by selling electricity or heat as long as their marginal revenue exceeds their marginal costs of production. This so called ’throughput incentive’ fundamentally restricts the motivation of utilities to invest in energy efficiency. This paper therefore investigates the relation between the regulatory policy revenue decoupling, that separates utilities’ revenue from sales fluctuations, and electricity customers’ energy demand and efficiency in the U.S. To address the research question at hand, we follow recent developments in energy demand function modeling and Stochastic Frontier Analysis (SFA) estimation techniques that allow to account for persistent as well as transient efficiency. The estimation results show a signif- icant negative correlation between revenue decoupling and electricity consumption patterns. Furthermore, we find electricity customers have small transient inefficiency. However, results indicate an underlying persistent inefficiency across the entire electric sector.
Determinants of Crop Choices by Bangladeshi Farmers: A Bivariate Probit Analysis
Creators: name: Rahman, Sanzidur
name: Rahman, Sanzidur
Publisher: name: Unknown
Year: 2008
Subjects: Agricultural and Food Policy

description: Using a bivariate probit model, the study jointly determines the factors underlying the probability of Bangladeshi farmers adopting a diversified cropping system and/or modern rice technology. Results reveal that the availability of irrigation is the single most important determinant of the decision to adopt modern rice technology, and adoption is higher among the tenant farmers. The exact opposite is true for the likelihood of adopting a diversified cropping system, which is significantly higher in areas with no irrigation as well as among the owner- operators. Furthermore, the diversified cropping system has a significantly higher rate of adoption in regions with developed infrastructure. Farmers’ education, farming experience, farm asset ownership, and non-agricultural income all positively influence crop diversification. Also, small farmers are more likely to adopt a diversified cropping system. Significant regional variation exists in the level of crop diversification as well. The decision to adopt a diversified cropping system and/or modern rice technology is significantly correlated, implying that a univariate analysis of such decision is biased. Crop diversification can be promoted by investing in farmers’ education as well as rural infrastructure development. Also, land reform policies focusing on delegating land ownership to landless and marginal farmers, and tenurial reforms are noteworthy.
MOESM2 of Systematic review of the use of process evaluations in knowledge translation research
Creators: name: Scott, Shannon
name: Rotter, Thomas
name: Flynn, Rachel
name: Brooks, Hannah
name: Plesuk, Tabatha
name: Bannar-Martin, Katherine
name: Chambers, Thane
name: Hartling, Lisa
Publisher: name: figshare
Year: 2019
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Additional file 2. PRISMA Checklist. Completed PRISMA checklist.
Cerapus volucola Lowry and Berents 2005
Creators: name: Just, Jean
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Ischyroceridae
Cerapus
Cerapus volucola

description: Cerapus volucola Lowry and Berents, 2005
(Fig. 7)
 Cerapus volucola Lowry & Berents, 2005: 160, figs 7–9.
 Type locality. False Orford Ness, north-east of Cape York, Australia.
 Habitat. Algal or seagrass dwellers. Littoral; 3–38 m.
 Tube. A cylindrical wrap of seagrass and algae.
 Remarks. Lowry & Berents (2005) reported Cerapus volucola from near Lizard Island. The species was not found during the present survey. Cerapus volucola differs from C. nudus sp. nov. in many characters, including coxae 1–4 fused to pereonites (coxa 1 in female not fused); coxae 3 and 4 with acute anteroventral lobe; a sharply acute rostrum (dorsal view); shorter antennae with more flagellar articles; dactylus of gnathopod 2 with posterior row of long setae; all pereopods with more and longer setae; telson lobes with 14– 15 dorsal hooks in 2 rows; tube constructed of plant material.
 Distribution. Australia. Entire Great Barrier Reef south to North Stradbroke Island (Lowry & Berents 2005). Papua New Guinea. Madang Lagoon (Lowry & Berents 2005).
description: Published as part of Just, Jean, 2009, Ischyroceridae *, pp. 463-486 in Zootaxa 2260 (1) on pages 473-475, DOI: 10.11646/zootaxa.2260.1.27, http://zenodo.org/record/10093465
MOESM2 of Contacting out-of-hours primary care or emergency medical services for time-critical conditions - impact on patient outcomes
Creators: name: Søvsø, Morten
name: Christensen, Morten
name: Bech, Bodil
name: Christensen, Helle
name: Christensen, Erika
name: Huibers, Linda
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 2. Adjusted analysis of the association between OOH service, ICU stay and mortality (N = 6826). Analysis of the association between OOH service, 1- and 1–30-day mortality and ICU stay. Adjusted for age, gender, ethnicity, employment status, education level, income level & comorbidity. * NR = not reported due to too few observations.
Eikan shiryaku, 6
瀛環志略 六
Creators: name: Inoue, Shunyō.
Publisher: name: Tokushima : Konishi Kichibei and Miyajimaya Izaemon
Year: 2021

description: Roads, towns and provinces indicated. Chinese title: Ying huan zhi lue, by Xu Ji Yu (Chinese) published in 1849; 43 maps, based on western cartography.
title: Complexicity of ECB Communication and Financial Market Trading
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Hayo, Bernd
name: Henseler, Kai
name: Rapp, Marc Steffen
name: Zahner, Johannes
Publisher: name: Philipps-Universität Marburg
Year: 2019
Subjects: ECB
linguistic complexity
textual analysis
European stock markets
Economics
Wirtschaft
readability
financial markets
central bank communication

description: We empirically examine how complexity of ECB communications affects financial market trading based on high-frequency data from European stock index futures trading. Our sample covers ECB press conferences between January 2009 and December 2017, during which un-conventional monetary policy measures (UMPM) substantially increased communication com-plexity. Analysing the linguistic complexity of the introductory statements and differentiating between press conferences with and without UMPM-announcements, we find more complex communication, i.e. high linguistic complexity and UMPM-announcement, is associated with a lower level of contemporaneous trading activity. Moreover, complex communication leads to a temporal shift in trading activity towards the subsequent Q&A session, which suggests that Q&A sessions facilitate market participants’ information processing. Finally, we document a relatively lower similarity of unconventional monetary policy statements and argue that this might explain our findings.
Topological-darkness-assisted phase regulation for atomically thin meta-optics
Creators: name: Wang, Yingwei
name: Deng, Zi-Lan
name: Hu, Dejiao
name: Yuan, Jian
name: Ou, Qingdong
name: Qin, Fei
name: Zhang, Yinan
name: Ouyang, Xu
name: Peng, Bo
name: Cao, Yaoyu
name: Guan, Bai-ou
name: Zhang, Yupeng
name: He, Jun
name: Qiu, Chengwei
name: Bao, Qiaoliang
name: Li, Xiangping
Publisher: name: arXiv
Year: 2019
Subjects: subject: Optics (physics.optics)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Two-dimensional (2D) noble-metal dichalcogenides have emerged as a new platform for the realization of versatile flat optics with a considerable degree of miniaturization. However, light field manipulation at the atomic scale is widely considered unattainable since the vanishing thickness and intrinsic losses of 2D materials completely suppress both resonances and phase accumulation effects. Empowered by conventionally perceived adverse effects of intrinsic losses, we show that the structured PtSe2 films integrated with a uniform substrate can regulate nontrivial singular phase and realize atomic-thick meta-optics in the presence of topological darkness. We experimentally demonstrate a series of atomic-thick binary meta-optics that allows angle-robust and high unit-thickness diffraction efficiency of 0.96%/nm in visible frequencies, given its thickness of merely 4.3 nm. Our results unlock the potential of a new class of 2D flat optics for light field manipulation at an atomic thickness.
The Kepler Peas in a Pod Pattern is Astrophysical
Creators: name: Weiss, Lauren M.
name: Petigura, Erik A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: \Kepler\ planets around a given star have similar sizes to each other and regular orbital spacing, like "peas in a pod." Several studies have tested whether detection bias could produce this apparent pattern by resampling planet radii at random and applying a sensitivity function analogous to that of the Kepler spacecraft. However, \citet{Zhu2019} argues that this pattern is not astrophysical but an artifact of Kepler's discovery efficiency at the detection threshold. To support this claim, their new analysis samples the transit signal-to-noise ratio (SNR) to derive a synthetic population of bootstrapped planet radii. Here, we examine the procedure of sampling transit SNR and demonstrate it is not applicable. Sampling transit SNR does not set up random, independent planet radii, and so it is unsuitable for corroborating (or falsifying) detection bias as the origin of apparent patterns in planet radius. By sampling the planet radii directly and using a simple model for Kepler's sensitivity, we rule out detection bias as the source of the peas-in-a-pod pattern with $>10$-$σ$ confidence.
description: Accepted for publication in ApJ Letters; 11 pages, 4 figures
A conservative diffuse-interface method for compressible two-phase flows
Creators: name: Jain, Suhas S.
name: Mani, Ali
name: Moin, Parviz
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In this article, we propose a novel conservative diffuse-interface method for the simulation of immiscible compressible two-phase flows. The proposed method discretely conserves the mass of each phase, momentum and total energy of the system. We use the baseline five-equation model and propose interface-regularization (diffusion--sharpening) terms in such a way that the resulting model maintains the conservative property of the underlying baseline model; and lets us use a central-difference scheme for the discretization of all the operators in the model, which leads to a non-dissipative implementation that is crucial for the simulation of turbulent flows and acoustics. Furthermore, the provable strengths of the proposed model are: (a) the model maintains the boundedness property of the volume fraction field, which is a physical realizability requirement for the simulation of two-phase flows, (b) the proposed model is such that the transport of volume fraction field inherently satisfies the total-variation-diminishing property without having to add any flux limiters that destroy the non-dissipative nature of the scheme, (c) the proposed interface-regularization terms in the model do not spuriously contribute to the kinetic energy of the system and therefore do not affect the non-linear stability of the numerical simulation, and (d) the model is consistent with the second law of thermodynamics. Finally, we present numerical simulations using the model and assess (a) the accuracy of evolution of the interface shape, (b) implementation of surface tension effects, (c) propagation of acoustics and their interaction with material interfaces, (d) the accuracy and robustness of the numerical scheme for simulation of complex high-Reynolds-number flows, and (e) performance and scalability of the method.
description: 50 pages, 24 figures
title: Trump Pressuring the Fed
title: MAGKS - Joint Discussion Paper Series in Economics
Creators: name: Tillmann, Peter
Publisher: name: Philipps-Universität Marburg
Year: 2019
Subjects: Federal Reserve
Economics
Wirtschaft
yield curve
monetary policy
political economy
central bank independence

description: After appointing Federal Reserve Chairman Powell, President Trump steadily
put pressure on the Fed to cut interest rates. We show that, on average, a
statement from Trump led to lower long-term interest rates, consistent with
expectations of lower expected future short rates. However, the impact of
Trump's statements declined over time.
Analysis of the interaction behavior between Nano-Curcumin and two human serum proteins: Combining spectroscopy and molecular stimulation to understand protein-protein interaction
Creators: name: Mokaberi, Parisa
name: Babayan-Mashhadi, Fatemeh
name: Zadeh, Zeinab Amiri Tehrani
name: Saberi, Mohammad Reza
name: Jamshidkhan Chamani
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: In this study, we have investigated the effects of Nano-curcumin (Nano-CUR) binding on HSA-HTF interactions as binary and ternary systems, which had been done through multiple spectroscopic and MD simulation. It has been indicated by fluorescence spectroscopy that Nano-CUR is capable of quenching both proteins with a static mechanism. Thermodynamic parameters have been calculated by considering the fluorescence data at different temperatures. The binding constants of HSA-Nano-CUR, HTF-Nano-CUR and (HSA-HTF) Nano-CUR complexes formation were (2.03 ± 0.32)×107 M−1, (2.46 ± 0.32)×106 and (4.54 ± 0.32)×106 M−1 respectively. According to the negative values of ΔH0 and ΔS0, the roles of van-der-Waals forces and hydrogen bond are quite essential throughout this particular binding. Besides, the negative ΔH0 and ΔS0 values of HTF (Nano-CUR) have been larger than those of the HSA (Nano-CUR) and HSA-HTF (Nano-CUR), which demonstrates the higher significance of interaction bonding. As it had been detected through the synchronized fluorescence spectroscopy at Δλ = 60nm, the position of Nano-CUR with mixed protein in ternary system has been closer to Tyr residues. Relatively, the binding distances between Trp residues of HSA and HTF in HSA (Nano-CUR), HTF (Nano-CUR), and (HSA-HTF Nano-CUR) complexes, which had been procured in accordance with the fluorescence resonance energy transfer (FRET), have been found to be 1.82nm, 1.87nm, and 1.92nm, respectively. We have evaluated the induced conformational changes of two proteins throughout the binding of Nano-CUR to HSA and HTF as binary and ternary systems by employing the CD technique, while the formation of self-assemblies has been studied through MD simulation.