cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Combining the Immunogenic Cancer Mutanome with Oncolytic Virus Therapy
Creators: name: Marguerie, Monique
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: oncolytic virus
mutanome
multi-epitope
prime-boost
maraba
adenovirus

description: Oncolytic viruses (OVs) are effective anti-cancer agents, however their abilities to induce anti-tumor immunity are not yet optimal. Mutanome epitopes are a novel source of tumor antigen formed as a result of mutations within the tumor genome. Within this project we attempted to combine B16F10 mutanome vaccination with OV therapy. We confirmed previous findings that significant immune responses to these epitopes can be generated. Furthermore, we designed and cloned a multi-epitope mutanome construct into MG1 Maraba virus and E1-/E3- deleted type 5 Adenovirus to use for heterologous prime-boost vaccination. While we demonstrated that these viruses induced T-cell responses to one mutanome epitope, we failed to detect responses to the other epitopes. Furthermore there was no effect seen on overall survival. This approach warrants further investigation because coupling mutanome vaccination with OV therapy has the potential to exploit the therapeutic effects of the OV while inducing anti-tumor immunity to tumor-unique antigens.
Plasmonic enhanced light absorption for silicon wafer-based solar cells
Creators: name: Zhang, Yinan
Publisher: name: Swinburne
Year: 2024

description: This research investigated the cutting-edge technology nanophotonics to enhance the light absorption in the silicon wafer solar cells thereby an energy conversion efficiency boost. One achievement of this research is to use low cost and innovative aluminium nanoparticles to enhance the solar cell efficiency and the other is to use plasmonic nanoparticles to maintain the solar cell efficiency while the thickness of the material is reduced. This research provides a low cost solution for the high efficiency solar cells, which would promote the solar cell development as one of the promising renewable and clean technologies.
In Vitro Simulation of Modular Neck Fracture, Wear, Corrosion, and Distraction in Total Hip Replacements
Creators: name: Aljenaei, Fahad
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: hip implant
modular neck
fracture
wear-corrosion

description: Total hip replacements are being used to relieve pain and restore the hip function of unhealthy hip joints. The various sizes and geometries of the modular femoral neck implants allow the surgeon to optimize the range of motion and patient’s leg length. However, some in vivo modular femoral neck retrievals have shown early fatigue and advanced wear-corrosion at the neck-stem taper interface, which can lead to adverse tissue reactions and failure of the implant. The overall objective of this study was to simulate in vivo fatigue fracture, wear, and corrosion of modular necks at the neck-stem taper interface in a laboratory setting (in vitro) to better predict the failure mechanisms and implant limitations. More specifically, after optimizing the laboratory setup and the testing conditions, this study aimed to compare the effects of the modular neck material (Ti6Al4V and CoCrMo) and the implant assembly technique (hand and impact assembly) on fatigue life, wear-corrosion resistance, and distraction force. The PROFEMUR® Modular Neck System with CoCrMo femoral heads and Ti6Al4V stems was used in this study. The in vitro simulation was divided into two types of tests: fatigue tests (high compression load for a short cyclic loading duration) and corrosion tests (low compression load for a long cyclic loading duration). The neck-stem interface was submersed in a phosphate buffered saline solution, which was maintained at a temperature of 80 ºC to accelerate the corrosion reaction. The simulation results showed that the Ti6Al4V necks were more vulnerable to fatigue fracture than CoCrMo necks. In addition, impact assembly of the components resulted in an increased implant fatigue life compared to hand assembly, but also increased the distraction force. The observed wear-corrosion damage was higher in fatigue tests than corrosion tests, suggesting that the level of mechanical load was a major factor influencing implant surface damage and fatigue fracture. On the other hand, corrosion tests showed that longer exposure resulted in more fluid accumulation in the stem pocket. This may lead to the formation of a corrosion cell with strongly acidic conditions in the stem pocket, as well as the potential for larger metal ion release. Overall, the in vitro simulation was successful in reproducing femoral modular neck fracture and wear-corrosion damage similar to retrieved in vivo specimens. Results may play a major role in the future development of total hip replacements and international standards for implant testing.
Numerical Reaction-transport Model of Lake Dynamics and Their Eutrophication Processes
Creators: name: Stojanovic, Severin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: limnology
reaction-transport
modelling
modeling
lake
eutrophication
numerical
turbulence
fluid
hydrodynamic
trophic
self-consistent trophic state index
sctsi
reaction transport

description: A 1D numerical reaction-transport model (RTM) that is a coupled system of partial differential equations is created to simulate prominent physical and biogeochemical processes and interactions in limnological environments. The prognostic variables considered are temperature, horizontal velocity, salinity, and turbulent kinetic energy of the water column, and the concentrations of phytoplankton, zooplankton, detritus, phosphate (H3PO4), nitrate (NO3-), ammonium (NH4+), ferrous iron (Fe2+), iron(III) hydroxide (Fe(OH)3(s)), and oxygen (O2) suspended within the water column. Turbulence is modelled using the k-e closure scheme as implemented by Gaspar et al. (1990) for oceanic environments. The RTM is used to demonstrate how it is possible to investigate limnological trophic states by considering the problem of eutrophication as an example. A phenomenological investigation of processes leading to and sustaining eutrophication is carried out. A new indexing system that identifies different trophic states, the so-called Self-Consistent Trophic State Index (SCTSI), is proposed. This index does not rely on empirical measurements that are then compared to existing tables for classifying limnological environments into particular trophic states, for example, the concentrations of certain species at certain depths to indicate the trophic state, as is commonly done in the literature. Rather, the index is calculated using dynamic properties of only the limnological environment being considered and examines how those properties affect the sustainability of the ecosystem. Specifically, the index is calculated from a ratio of light attenuation by the ecosystem’s primary biomass to that of total light attenuation by all particulate species and molecular scattering throughout the entire water column. The index is used to probe various simulated scenarios that are believed to be relevant to eutrophication: nutrient loading, nutrient limitation, overabundance of phytoplankton, solar-induced turbulence, and wind-induced turbulence.
Marktmacht bündeln
Creators: name: Rubik, Frieder
name: Müller, Ria
name: Hinke, Corinna
Publisher: name: My University
Year: 2015
Subjects: subject: Innovation
subject: Öko-Innovation
subject: Nachfrageeffekt
subject: Industrie-Umweltpolitik
subject: Beschaffung
subject: Nachhaltiger Konsum
subject: Großverbraucher
subject: Umweltinnovation
subject: Massenmarkt
subject: Wirtschaft | Konsum
subject: Economy | Consumption

description: Die Studie liefert einen systematischen Überblick über relevante nicht-öffentliche Großverbraucher in Deutschland in sechs Gütergruppen (Elektromotoren, Innenraumbeleuchtung, Textilien, Reinigungsmittel, Hartbodenbeläge und IT/IKT-Geräte). Sie identifiziert 30 Umweltinnovationen mit hoher ökologischer Relevanz, für die es Großverbraucher gibt. Im Rahmen des Vorhabens wurden drei Workshops mit Großverbrauchern zu folgenden Themen durchgeführt: Pkw-Klimaanlagen mit ⁠CO2⁠ als Kühlmittel, Energieeffiziente Textiltrocknung, Biobaumwolle und Recyclingbaumwollfasern. Der Bericht kommt zum Schluss, dass die Aktivierung von Großverbrauchern vielversprechend ist. Sie könnte den bisherigen Fokus auf die öffentliche Beschaffung und private Endverbraucher sinnvoll ergänzen und erweitern.Denn es gibt in vielen umweltrelevanten Produktkategorien Großverbraucher, die einen signifikanten Anteil der Nachfrage des Gesamtmarktes abdecken. So repräsentierten die fünf Firmenvertreter im Workshop zu Pkw-Klimaanlagen alleine rund 100.000 Pkw in Deutschland und 800.000 Pkw weltweit. Das Vorhaben und die Workshops haben gezeigt, dass nicht nur die öffentliche Hand, Hersteller und Verbraucher, sondern auch nicht-öffentliche Großverbraucher für die Umweltpolitik sehr interessante und effektive Partner bei der Förderung von Umweltinnovationen und umweltfreundlichen Produkten sein können. Dabei stellt der Dialog mit Großverbrauchern ein geringinvestives Instrument zur Förderung umweltfreundlicher Produkte dar. Der Bericht empfiehlt, zum Beispiel im Rahmen von Aufklärungskampagnen zur öffentlichen Beschaffung auch gezielter Angebote in Richtung nicht-öffentliche Beschaffer zu machen. Umso mehr, da die Grenzen zwischen öffentlicher und nicht-öffentlicher Beschaffung vielfach fließend sind.
Investigation of acoustical and mechanical properties of epoxy based natural fibre composites
Creators: name: Bakri, Muhammad Khusairy Bin
Publisher: name: Swinburne
Year: 2024

description: Noise is unwanted sound, which is harmful to our auditory system. Sound absorbing materials are used in reducing, eliminating or insulating the noise. Existing sound absorbing materials are mostly made from asbestos and synthetic materials, which are known to be harmful for the environment and health. Thus, this has motivated the initiative to develop alternative materials. In this research, natural waste product such as banana, luffa and oil palm fibre were blended with epoxy to form natural fibre composites. Mechel, and Delany and Bazley empirical models were used as a preliminary theoretical analysis in order to gain an understanding of the effect of thickness, fibre size, flow resistivity and types of fibre on sound absorption. The modelling showed that banana, luffa, and oil palm have almost similar sound absorption behaviour. Based on the empirical models, it showed that with increasing fibre diameter, the flow resistivity decreased, but the sound absorption still increased as long as the porosity is high. Furthermore, with increasing material thickness, an increase in the sound absorption is expected. Lastly, the modelling results showed that the sound absorption, increased with increasing frequency. In the case of acoustical and mechanical characterisation, it was revealed that the fibre loading and alkaline treatment have a significant effect. It was found that the sound absorption coefficient for the composites tested increased with increasing fibre loading. The result also showed that the treated fibre gives better sound absorption compared to the untreated counterpart. The treatment caused removal of certain wax, oil, and certain structure (i.e. such as hemicellulose, cellulose, and lignin), which improved the tensile and yield strength of the natural fibre composite materials. Chemical treatment caused break, stretch or bend in the H, OH and CH bond structure of the fibres which were validated by using Fourier transform infrared spectral analysis. Furthermore, the changes on the surface roughness and the structure of the fibre can be seen using scanning electron microscope and light/optical microscope. It showed that the treated fibre have a rougher surface and larger lumen structure than the untreated fibre. Based on the result of acoustical and mechanical test, it was concluded that the novel composites developed would find new applications for agricultural waste and reduced oil-derived polymers.
Triterpene Carboxylic Acids as Cortisol Lowering Agents and Synthesis of Hexadeuterated Beta-Ionone
Creators: name: Mogg, Trevor
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Betulinic Acid
Ursolic Acid
Cortisol
Oleanolic Acid
Triterpene Carboxylic Acids
beta-ionone
deuterated
beta ionone
cortisol lowering
synthesis of beta ionone
synthesis of beta-ionone
deuterium labeled
ionone

description: In part one, betulinic acid (1) was isolated from the American Sycamore (Platanus occidentalis) in 1.6% yield, while ursolic acid (3) was isolated from Fuji and McIntosh apple peels in 1.0% and 0.8% crude yields, respectively. Oleanolic (4) and dehydrocanophyllic (6) acids were previously available, along with several analogs. Additional analogs of 1, 3 and 4 were prepared, including 9 new compounds, for a total of 51 compounds. Compounds were initially screened for cortisol lowering properties in vitro using a fish head kidney cell assay. Platanic acid (43) was selected for in vivo study in rats, along with 1 and a blend of Platanus occidentalis and Souroubea sympetela. No significant cortisol lowering was observed in vivo. In part two, β-ionone-d6 (75) was synthesized in 6.5% yield from ethyl 2-oxo-cyclohexane carboxylate (77). Total deuterium incorporation was 99.85%, with 0.03% d0 analog. 75 was converted to retinoic acid-d6 (93) in 2.2% yield.
Characterizing Rho Kinase Activity Using a Novel PET Tracer in Hypertrophied Cardiomyocytes
Creators: name: Moreau, Steven
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: cardiac hypertrophy
rho kinase
positron emission tomography
N-[11C]-methyl-hydroxyfasudil

description: Cardiac hypertrophy is a compensatory response to increased work load or stress on the heart, but over time can lead to heart failure and death. The molecular mechanisms underlying this disease are still not completely understood, however the Rho/Rho kinase pathway has been shown to play a role. N-[11C]-methyl-hydroxyfasudil, a PET radiotracer, binds to active Rho kinase and could be a possible tracer for hypertrophy. Hypertrophy was induced in vitro using the β-adrenergic receptor agonist isoproterenol to evaluate optimal Rho kinase activity. Rho kinase activity data was correlated to N-[11C]-methyl-hydroxyfasudil binding. Cardiac hypertrophy was verified with an increase in nuclear size (1.74 fold) and cell size (~2 fold), activation of hypertrophic signalling pathways, and increased Rho kinase activity (1.64 fold). This correlated to a 10.3% increase in N-[11C]-methyl-hydroxyfasudil binding. This data suggests that N-[11C]-methyl-hydroxyfasudil may be useful as a radiotracer for detecting cardiac hypertrophy and merits further in vivo investigation.
Connecting Metal-Support Interaction and Electrochemical Promotion Phenomena for Nano-structured Catalysts
Creators: name: Dole, Holly
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Electrochemical promotion
Heterogeneous catalysis
Metal-support interaction
Nanoparticles
Oxidation

description: Air pollutants can cause poor air quality; however, the use of heterogeneous catalytic oxidation has been shown to be an efficient and cost-effective removal method. Some examples of commercial application of such catalysts include catalytic convertors in automobiles and industrial process exhausts. Research with regards to improving these technologies has included using less-expensive catalyst materials, increasing catalytic performance, and achieving higher efficiency. The concept of metal-support interaction (MSI) is one method of altering catalytic performance through changing the properties of the metal catalyst due to the interaction with the support material. Similarly, the phenomenon of electrochemical promotion of catalysis (EPOC) has also been shown to enhance the catalytic activity, however, through the application of a small electrical stimulus to a catalyst-working electrode deposited on a solid electrolyte (e.g. yttria-stablized zirconia). The properties of the metal catalyst are altered due to the movement of ions (in this case, O2-) from the electrolyte. Since its discovery, several factors were identified that are preventing EPOC from being commercialized, including the use of thick film catalysts. Implementing nano-catalysts makes this method competitive with typical heterogeneous catalysts; however, it has not been studied by many research groups. Furthermore, many heterogeneous catalytic studies have been performed separately for each of these phenomena; however, a connection between EPOC and MSI has yet to be fully understood. The overall objective of this project is to study the concept of EPOC over highly-dispersed nano-catalysts and determine how MSI relates to the change in catalytic activity. Supported nano-catalysts were synthesized, characterized, and evaluated for catalytic performance using model reactions. A reactor was designed to carry out the electrochemical studies, where the EPOC concept was successfully implemented and a relationship with MSI established. Furthermore, additional studies were conducted to determine the role of the O2- in the catalyst support and its relationship to MSI.
Transformationsforschung
Creators: name: Wittmayer, Julia
name: Hölscher, Katharina
Publisher: name: My University
Year: 2017
Subjects: subject: Transformationsforschung
subject: Nachhaltigkeitstransformation
subject: transformative Forschung
subject: Forschungsmethoden
subject: Nachhaltigkeit | Strategien | Internationales

description: Es gibt immer mehr Forschungen, die sich mit Veränderungsprozessen in Richtung ⁠Nachhaltigkeit⁠ beschäftigen und sich Transformationsforschung nennen. Transformationsforschung gibt es in verschiedenen Forschungsrichtungen, zu verschiedenen Themenfeldern (z.B. Konsum, Mobilität, Energie) und mit verschiedenen Schwerpunkten und Methoden. Dies macht einerseits die Transformationsforschung reichhaltig, andererseits ergibt sich daraus die Notwendigkeit einer deutlicheren Strukturierung und Abgrenzung. In dieser Studie leisten wir einen Beitrag zur Diskussion rund um die Transformationsforschung und adressieren u.a. Fragen über deren Ziele, Inhalte, Forschungsansätze und geben eine Methodenübersicht.
Delays at Canberra: why Australia should have built fast rail decades ago
Creators: name: Newton, Peter
Publisher: name: Swinburne
Year: 2024

description: The front-page headlines generated this week by Prime Minister Malcolm Turnbull's promise to link Australia's major eastern cities by fast rail may be seen by many voters as yet another major infrastructure pledge made hurriedly in the run-up to a federal election that is likely to evaporate just as quickly afterwards. Fast intercity rail certainly has form when it comes to being put on the table only to be whipped away again. Linking Australia's two biggest cities by rail would be in the same nation-building category as the Snowy Mountains Scheme, yet we have been talking about it for decades without actually doing it. How different might things be now if Australia had built the Very Fast Train (VFT), first proposed in 1984 by the then CSIRO chairman, Paul Wild. The plan (on which I worked) attracted the support of leading companies of the day, including BHP and Elders IXL, but was bogged down in taxation issues and eventually scrapped in 1991.
Mythical Islands of Value: Free Ports, Offshore Capitalism, and Art Capital
Creators: name: Post, Erik
name: Calvão, Filipe
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2021

description: The Geneva Free Port in Switzerland has paved the way for a new generation of art and luxury free ports. These are critical spatial pivots for the management of art assets, including storage and transactions of artworks, and serve as proxy to examine mechanisms for the capture and generation of value, integral but also outside the global art market. Drawing from the trajectory of the Geneva Free Port and an interdisciplinary body of scholarship on “offshore” and other special zones of production, and value circulation in human geography, anthropology, history, and sociology, this article frames free ports in a longer genealogy of offshore capitalism. First, we claim that the emergence of the Geneva Free Port prefigures and helps illuminate contemporary transformations in offshore capitalism; second, these spaces are more deeply imbricated with public and state authorities than previously suggested. Finally, a holistic understanding of art capital—works of art for investment and asset management—requires an encompassing view of free ports not as accidental and exceptional features in the world of high art but as spaces deeply implicated in the creation and operation of the art market more generally.
Measuring Food Volume and Nutritional Values from Food Images
Creators: name: Al-Maghrabi, Rana
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Obesity
calories assumption
image processing

description: Obesity and being overweight have become growing concerns due to their association with many diseases, such as type II diabetes, several types of cancer and heart disease. Thus, obesity treatments have been the focus of a large number of recent studies. Because of these studies, researchers have found that the treatment of obesity and being overweight requires constant monitoring of the patient’s diet. Therefore, measuring food intake each day is considered an important step in the success of a healthy diet. Measuring daily food consumption for obese patients is one of the challenges in obesity management studies. Countless recent studies have suggested that using technology like smartphones may enhance the under-reporting issue in dietary intake consumption. In this thesis, we propose a Food Recognition System (FRS) for calories and nutrient values assumption. The user employs the built-in camera of the smartphone to take a picture of any food before and after eating. The system then processes and classifies the images to detect the type of food and portion size, then uses the information to estimate the number of calories in the food. The estimation and calculation of the food volume and amount of calories in the image is an essential step in our system. Via special approaches, the FRS can estimate the food volume and the existing calories with a high level of accuracy. Our experiment shows high reliability and accuracy of this approach, with less than 15% error.
Smart mobility research facility
Creators: name: Dia, Hussein
Publisher: name: Swinburne
Year: 2024

description: This presentation describes the Smart Mobility Research Facility at Swinburne University of Technology. This Facility comprises a virtual transport modelling platform hosted at the Hawthorn Campus where significant research in smart mobility is being conducted. The Facility is used to pre-process and analyse field data from real-life networks in Melbourne for subsequent use in modelling and testing of different mobility solution scenarios. The Facility is intended to enable Swinburne's multi-disciplinary researchers and industry practitioners to demonstrate the readiness of advanced systems and accelerate deployment of multi-modal smart transport technologies through testing of prototypes in a simulation environment. The multi-disciplinary research program supported under this Facility includes projects that will directly benefit both fundamental and applied research in this field. The talk will discuss the main components of the simulation platform and present examples of case studies including simulations of impacts of driverless vehicles and autonomous mobility on demand systems. The establishment of this Facility presents a unique opportunity to enhance support for Australian research and innovation by building on the success of Australian smart mobility technologies and intellectual capital. The facility also represents a major investment in the future of smart mobility research in Australia and will provide a unique training ground for students, staff and industry practitioners.
'But She Doesn't DO Anything!' Framing and Containing Female Celebrity in the Age of Reality Television
Creators: name: Patrick, Stephanie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Reality television
Feminism
News
Discourse analysis
Authenticity
Talent
Containment
Celebrity

description: This thesis offers a feminist analysis of the gendered public discourses surrounding notions of talent, authenticity and containment. Using two of the most polarizing stars in North America – ‘Snooki’ and Kim Kardashian – the author offers an analysis of how both hard and soft news frame our everyday understanding of women’s public work. Textual analyses of news articles demonstrated that displays of sexual power were most undermined by the media while attempts to venture beyond the reality television texts were contained. On the other hand, the news media were more likely to use positive framing when women were seen to be fulfilling more traditional roles such as wife and mother. The empirical research approach provides an original framework which can be applied to other female public figures to examine how such ideological and gendered discourses shape our understanding of women’s work as well as, more generally, women’s roles in our society.
Integration by Popular Culture: Brigitte Bardot as a Transnational Icon and European Integration in the 1950s and 1960s
Creators: name: Sherwood, Dana Whitney
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: popular culture
Brigitte Bardot
European integration
mobility
ideology
postwar film
fashion
consumer culture
travel
tourism
celebrity
Europeanization
youth culture

description: This thesis explores the history of European integration in the 1950s and 1960s from a popular cultural perspective anchored to a central figure from the era, Brigitte Bardot, in order to demonstrate that the peoples of Western Europe were engaged in processes of Europeanization that helped legitimize economic and political unions. Yet, official EU policy’s privileging of one (outdated) mode for understanding culture has handicapped alternative interpretations of a common European cultural heritage, failing to embrace a shared popular culture. Bardot is a suitable icon through which to begin an exploration into the diversity and significance of an integrating postwar European popular culture because she was a microcosm of several broad, transnational trends in postwar Europe including the rise of mass mobility, a major shift in European fashions, new gender constructions, and the explicit politicization of popular culture. Her films, career, lifestyle, and representation(s) provide key axes from which one can pivot into interrelated areas of European culture and societies in this era—pop culture; consumer culture; youth culture; mobility culture; media culture; political culture; and gender relations—demonstrating a widely integrating European popular cultural sphere. Within this context, Bardot was representative of broad postwar societal changes, served as a mass diffusion tool in relating these changes to the people of Europe, and functioned as a driving force in creating new transnational popular cultural forms. In addition, Bardot is a figure useful in understanding the relationship between Europe and the United States, while also demonstrating that economics is not separate from culture and popular culture. The Treaty of Rome, ostensibly about economic integration, further enabled the many circulations apparent in Bardot's career—people, goods, information, and ideas—that were already taking place. Furthermore, popular culture was not irrelevant to, or separate from politics and it helps to explain how the escapism and narcissism of European popular consumer culture could generate a rebellious, but sophisticated political consciousness. Western Europe does indeed have a distinct history of shared popular culture, which should be a factor in discussions of ‘Europeanization’ and the legitimacy of the European Union. It is necessary to explore the roots of this shared popular culture so that it does one day form the basis of a longstanding shared popular culture and can become a recognized element supporting the legitimacy of identities in the European Union in more fluid, dynamic ways.
title: Ermittlung der analytischen Unsicherheit für chemische Bodenuntersuchungen
title: Ermittlung der analytischen Unsicherheit für chemische Bodenuntersuchungen
titleType: AlternativeTitle
Creators: name: Uhlig, Steffen
name: Hettwer, Karina
name: Terytze, Konstantin
name: Simon, Kirsten
Publisher: name: My University
Year: 2020

description: The methodology for determining measurement uncertainty for implementation of the Federal Soil Protection and Contaminated Sites Ordinance (Bundes-Bodenschutz- und Altlastenverordnung (BBodSchV) was further developed and updated based on data of proficiency tests (2005-2019). In comparison to the recommendations of the Advisory board for soil investigations (FBU) from 2008, an improved approach for modelling of the reproducibility standard deviation and related uncertainty was developed. With this newly developed approach, the analytical uncertainty can be calculated as a function of the contamination level. Especially for elements it is now possible to determine the analytical uncertainty specifically. Furthermore, recommendations for new parameters could be derived. Quelle: Ermittlung der analytischen Unsicherheit für chemische Bodenuntersuchungen : Empfehlungen für den Vollzug der BBodSchV / Steffen Uhlig ; Karina Hettwer ; Kirsten Simon ; Konstantin Terytze ; Deutschland. Umweltbundesamt. Fachgebiet II.2.6 - Maßnahmen des Bodenschutzes Affiliation. - 1 Onlineressource (Seiten 141-144) : Illustrationen. - Online-Ausgabe. In: Altlasten-Spektrum : Organ des ITVA. - (2020), Heft 04, Seite 144
Improving the estimation of agency cost associated with increasing axle mass limits
Creators: name: Mohammed, Bayar Najeeb Abdulrazaq
Publisher: name: Swinburne
Year: 2024

description: Due to the increased demand associated with rapid the population and economic growth in Victoria, the freight task is expected to increase at a high rate. Estimating the changes in deterioration rates of road pavements and associated damages due to increased volume of heavy freight vehicles and loading requires using reliable and accurate deterioration models. In this thesis, deterioration models of the Highway Development and Management (HDM-4) have been calibrated and used to estimate agency costs associated with different loading scenarios. These will be very useful for road authorities together with the interim pavement age models that have been developed for different road classes.
Effects of Extracellular Matrix Glycation on Cell and Tissue Function
Creators: name: Nadlacki, Borivoje Bora
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: methylglyoxal
myocardial infarction
endothelial cell
fibroblast

description: Methylglyoxal (MG) is a reactive dicarbonyl derived as a by-product of glycolysis. If MG is not metabolized by glyoxalase-1 (Glo1), it glycates macromolecules producing advanced glycation end products (AGEs); these have been linked to larger infarct sizes and poorer cardiac function after myocardial infarction (MI). Proteins of the extracellular matrix (ECM) are prime targets for glycation by MG, but it is unknown if MG modification of the ECM may be a mechanism that contributes to the poor repair and function of the post-MI heart. This study sought to examine if MG-induced modifications of ECM proteins negatively affect fibroblast and endothelial cell function. Analysis with an MG-derived hydroimidazolone 1 (MG-H1) antibody confirmed MG modification of laminin and collagen type (Col) 1, 3, and 4. MG modifications decreased endothelial cell (EC) adhesion on Col3, Col4, and laminin and angiogenesis on ECMatrix. Furthermore, alpha smooth muscle actin staining indicated increased myofibroblast differentiation of fibroblasts on MG-modified proteins. Following induction of MI, extracted mouse hearts were decellularized and compared to healthy controls. Perhaps a result of technical challenges, both western blot and immunohistochemistry contrasted previous data by displaying a marked decrease in MG-H1 modifications post-MI. Overall, these results indicate that MG modifications of the ECM negatively influence EC and fibroblast function, requiring more research on their impact in cardiovascular disease progression.
Travelling by bicycle in Australia, from nationalism to multi-culturalism... Brand names, marketing and national identity
Creators: name: Jackson, Simon
name: Renda, Gianni
Publisher: name: Swinburne
Year: 2024

description: With the Australian-owned and Taiwanese-manufactured bicycle Malvern Star launching its premier model named Oppy after world champion racer Sir Hubert Opperman, it is harking back to the glory years of Australian bicycling sporting success. This paper explores the history of the bicycle industry in Australia and the role played by product branding. It also documents the change from this nation starting as a largely British 'settler' society, and becoming a modern multi-cultural one.
Differences in adolescent activity and dietary behaviors across home, school, and other locations warrant location-specific intervention approaches
Creators: name: Ortega, Adrian
name: Bejarano, Carolina M
name: Cushing, Christopher C.
name: Staggs, Vincent S
name: Papa, Amy E
name: Steel, Chelsea
name: Shook, Robin P
name: Sullivan, Debra K
name: Couch, Sarah C
name: Conway, Terry L
name: Saelens, Brian E
name: Glanz, Karen
name: Frank, Lawrence D.
name: Cain, Kelli L
name: Kerr, Jacqueline
name: Schipperjin, Jasper
name: Sallis, James F
name: Carlson, Jordan A
Publisher: name: BioMed Central
Year: 2020

description: Background: Investigation of physical activity and dietary behaviors across locations can inform “setting-specific” health behavior interventions and improve understanding of contextual vulnerabilities to poor health. This study examined how physical activity, sedentary time, and dietary behaviors differed across home, school, and other locations in young adolescents. Methods: Participants were adolescents aged 12–16 years from the Baltimore-Washington, DC and the Seattle areas from a larger cross-sectional study. Participants (n = 472) wore an accelerometer and Global Positioning Systems (GPS) tracker (Mean days = 5.12, SD = 1.62) to collect location-based physical activity and sedentary data. Participants (n = 789) completed 24-h dietary recalls to assess dietary behaviors and eating locations. Spatial analyses were performed to classify daily physical activity, sedentary time patterns, and dietary behaviors by location, categorized as home, school, and “other” locations. Results: Adolescents were least physically active at home (2.5 min/hour of wear time) and school (2.9 min/hour of wear time) compared to “other” locations (5.9 min/hour of wear time). Participants spent a slightly greater proportion of wear time in sedentary time when at school (41 min/hour of wear time) than at home (39 min/hour of wear time), and time in bouts lasting ≥30 min (10 min/hour of wear time) and mean sedentary bout duration (5 min) were highest at school. About 61% of daily energy intake occurred at home, 25% at school, and 14% at “other” locations. Proportionately to energy intake, daily added sugar intake (5 g/100 kcal), fruits and vegetables (0.16 servings/100 kcal), high calorie beverages (0.09 beverages/100 kcal), whole grains (0.04 servings/100 kcal), grams of fiber (0.65 g/100 kcal), and calories of fat (33 kcal/100 kcal) and saturated fat (12 kcal/100 kcal) consumed were nutritionally least favorable at “other” locations. Daily sweet and savory snacks consumed was highest at school (0.14 snacks/100 kcal). Conclusions: Adolescents’ health behaviors differed based on the location/environment they were in. Although dietary behaviors were generally more favorable in the home and school locations, physical activity was generally low and sedentary time was higher in these locations. Health behavior interventions that address the multiple locations in which adolescents spend time and use location-specific behavior change strategies should be explored to optimize health behaviors in each location.
title: A Multi-Scalar Socio-Policy Analysis of Resource Reallocation and Water Security in Twenty-First Century Utah, USA
Creators: name: Carney, Clint P.
Publisher: name: Utah State University
Year: 2022

description: As drought and a warming climate continue to impact the western United States, balancing the water needs of cities, agriculture, and natural systems is becoming increasingly more complex. One approach commonly promoted to address water supply issues is the transfer of water between users via markets. However, markets for water face multiple obstacles that can often be costly for participants due to constraints inherent in western U.S. water law. Coinciding with issues of cost, water markets must overcome disinterest among water rights holders in releasing their water rights for uses even if temporarily. Moreover, water transfers bring to light the potential impacts to security in access to water for other needs when water is moved between locations and uses.
This research examined key challenges to the establishment and use of market-based transfer arrangements known as water banks. Existing water banks in other states were first analyzed to assess how they have added flexibility to existing water law in order to address specific or broad impacts of water scarcity. Northern Utah’s Bear River Basin then served as a case setting to examine the complexities of establishing water banks through the perspectives of individual water users and others involved in water management. Data were collected through interviews, focus groups, observations of legislative workgroups, and analysis of existing literature.
This research found that the benefits of transfers through water banks are potentially dependent on the scale of interest that the transaction is assessed at and how the consumption of water is managed. Moreover, this work found that the prevailing behaviors and attitudes regarding water transfers are in part rooted in how existing water laws and organizations have controlled allocation and use of the resource. Understanding these social factors is critical to the policy designs of market-based approaches to sharing water that rely on participation of water rights holders to contribute towards rebalancing water supplies and meeting policy objectives at all scales of interest.
Instrumentation Development for Site-Specific Prediction of Spectral Effects on Concentrated Photovoltaic System Performance
Creators: name: Tatsiankou, Viktar
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: photovoltaics
concentrating photovoltaics
solar spectrum
solar cells
spectral irradiance
solar resource assessment
spectroradiometer
solar spectrum modelling
solar spectrum reconstruction
solar spectral irradiance meter
SSIM

description: The description of a novel device to measure the spectral direct normal irradiance is presented. The solar spectral irradiance meter (SSIM) was designed at the University of Ottawa as a cost-effective alternative to a prohibitively expensive field spectroradiometer (FSR). The latter measures highly-varying and location-dependent solar spectrum, which is essential for accurate characterization of a concentrating photovoltaic system’s performance. The SSIM measures solar spectral irradiance in several narrow wavelength bands with a combination of photodiodes with integrated interference filters. This device performs spectral measurements at a fraction of the cost of a FSR, but additional post-processing is required to deduce the solar spectrum. The model was developed to take the SSIM’s inputs and reconstruct the solar spectrum in 280–4000 nm range. It resolves major atmospheric processes, such as air mass changes, Rayleigh scattering, aerosol extinction, ozone and water vapour absorptions. The SSIM was installed at the University of Ottawa’s CPV testing facility in September, 2013. The device gathered six months of data from October, 2013 to March, 2014. The mean difference between the SSIM and the Eppley pyrheliometer was within ±1.5% for cloudless periods in October, 2013. However, interference filter degradation and condensation negatively affected the performance of the SSIM. Future design changes will improve the longterm reliability of the next generation SSIMs.
Not-so-Secret Authentication: The SyncBleed Attacks and Defenses for Zero-Involvement Authentication Systems
Creators: name: Ahlgren, Isaac
name: Shirsat, Rushikesh
name: Achkar, Omar
name: Thiruvathukal, George K.
name: In Lee, Kyu
name: Klingensmith, Neil
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 460499
subject: Cybersecurity and privacy not elsewhere classified

description: Zero-involvement authentication (ZIA) offers a promising solution for autoprovisioning large IoT device networks by enabling devices to extract identical authentication keys from ambient environmental signals without user intervention.However, we demonstrate that existing ZIA systems leak critical information during key negotiation when they exchange synchronization messages over public wireless channels. Our novel passive attack, SyncBleed, exploits these leaked messages to reconstruct ZIA-generated keys, successfully cracking approximately 50% of keys in under one second in our testbed experiments. To address this vulnerability, we introduce TREVOR (Time shift REsistant VEctor ExtractOR), which generates nearly identical bit sequences from environmental signals without exchanging any synchronization information. TREVOR produces keys in under 4~seconds with 90--95% bit agreement rates between legitimate devices across various environmental sources, while maintaining complete resistance to SyncBleed attacks.
Factors that Influence the Recognition, Reporting, and Resolution of Incidents Related to Medical Devices and an Investigation of the Continuous Quality Improvement Data Automatically Reported by Wireless Smart Infusion Pumps
Creators: name: Polisena, Julie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: medical devices
health technology
post-market surveillance
incidents
medication errors
infusion pumps
continuous quality improvement
patient safety
hospital

description: Medical devices are used to diagnose, treat, or prevent a disease or abnormal physical condition without any chemical action in the body. They can also result in unintended incidents and other errors. This thesis was divided into three chapters: i) a systematic review on the recognition, reporting and resolution of incidents related to medical devices and other health technologies; ii) telephone interviews with physicians and registered nurses (RNs) to solicit information on the resolution, reporting and resolution of medical device-related incidents based on their professional experience; and iii) a case study to review the continuous quality improvement (CQI) data retrieved from the wireless smart infusion pump system at The Ottawa Hospital (TOH) and to propose a CQI data analysis process. The systematic review included 30 studies on factors that influence the recognition, reporting and resolution of incidents in hospitals and interventions to improve patient safety. Central themes that emerged for incident reporting were personal attitudes, awareness and perception of incident reporting systems, organizational culture, and feedback to healthcare professionals. In our telephone interviews, physicians and RNs attributed incident recognition to devices not operating based on the manufacturer’s instructions, and to the hospital staff’s knowledge of and professional experience with the use of the medical device, and clinical manifestations of patients. Suggestions to improve medical device safety surveillance centered on education and training to ensure that the staff is able to use the medical device properly and know what would be considered an error, and how to report these errors. The results of the systematic review and interviews helped to inform the design of a medical device surveillance framework in a hospital setting. Our case study assessed the Dose Error Reduction Software compliance and frequency of soft and hard limit alerts with wireless smart infusion pump systems over a one year period. A CQI data analysis process to monitor the performance of wireless smart infusion pumps is proposed. The findings of this doctoral thesis can contribute to the development of a medical device surveillance system that would help to improve health care delivery and patient safety in a health care institution.
title: MENTAL CONTAMINATION, COPING, AND PTSD SYMPTOM SEVERITY FOLLOWING SEXUAL TRAUMA
Creators: name: Tipsword, Jordyn
Publisher: name: University of Kentucky Libraries
Year: 2020
Subjects: subject: FOS: Psychology

description: Mental contamination (MC) – an internal sense of dirtiness experienced without contact with a contaminant – has been linked to PTSD symptoms among sexual trauma survivors. However, existing work has been limited to cross-sectional or quasi-experimental designs – precluding conclusions concerning the directionality of associations among PTSD symptoms and MC – and little work has examined potential mediators of those associations. The present study utilized a prospective design to evaluate the directionality of associations between MC and PTSD symptoms and the role of avoidance and approach coping in mediating those associations. Participants included 41 women with a history of sexual trauma and current MC. Women completed baseline measures followed by fourteen days of twice-daily assessments via a mobile application. Results indicated that avoidance coping mediated the associations between baseline MC and average daily PTSD symptoms (β = 0.30, SE = 0.14, 95% CI [0.06 , 0.58]) and baseline PTSD symptoms and average daily MC (β = 0.33, SE = 0.16, 95% CI [0.08 , 0.67]). Our findings support a mutual maintenance model of PTSD symptoms and MC mediated by avoidance coping. However, additional research conducted over a more extended period is warranted to better understand how MC and PTSD symptoms mutually influence one another.
description: © 2020 Jordyn M. Tipsword