cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(101734) Eliza Curtis Hopkins
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Neisseria gonorrhoeae PilV, a type IV pilus-associated protein essential to human epithelial cell adherence
Creators: name: Koomey, M.
name: Hegge, F.T.
name: Winther-Larsen, H.C.
name: Hayes, S.F.
name: Wolfgang, M.
name: Van Putten, J.P.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Type IV pili (Tfp) of Neisseria gonorrhoeae, the Gram-negative etiologic agent of gonorrhea, facilitate colonization of the human host. Tfp are assumed to play a key role in the initial adherence to human epithelial cells by virtue of the associated adhesin protein PilC. To examine the structural and functional basis for adherence in more detail, we identified potential genes encoding polypeptides sharing structural similarities to PilE (the Tfp subunit) within the N. gonorrhoeae genome sequence database. We show here that a fiber subunit-like protein, termed PilV, is essential to organelle-associated adherence but dispensable for Tfp biogenesis and other pilus-related phenotypes, including autoagglutination, competence for natural transformation, and twitching motility. The adherence defect in pilV mutants cannot be attributed to reduced levels of piliation, defects in fiber anchoring to the bacterial cell surface, or to unstable pilus expression related to organelle retraction. PilV is expressed at low levels relative to PilE and copurifies with Tfp fibers in a PilC-dependent fashion. Purified Tfp from pilV mutants contain PilC adhesin at reduced levels. Taken together, these data support a model in which PilV functions in adherence by promoting the functional display of PilC in the context of the pilus fiber.
Effective Hamiltonian for a Half-filled Asymmetric Ionic Hubbard Chain with Alternating On-site Interaction
Creators: name: Grusha, Inna
name: Menteshashvili, Mikheil
name: Japaridze, George I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We derive an effective spin Hamiltonian for the one-dimensional half-filled asymmetric ionic Hubbard model with alternating on-site interaction in the limit of strong repulsion. It is shown that the effective Hamiltonian is that of a spin $S=1/2$ anisotropic $XXZ$ Heisenberg chain with alternating next-nearest-neighbor and three-spin couplings in the presence of a uniform and a staggered magnetic field.
description: Revtex version, 20 pages; no figures or tables
Racialized Incivility and Voice - US Merit Data Preregistration
Creators: name: Tenney, Elizabeth
name: Stillwell, Amelia
name: Figueroa, Alexandra
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Business
subject: Management Sciences and Quantitative Methods
subject: Industrial and Organizational Psychology
subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Preregistration of secondary data analysis for 2010 US Merit Board Data
Suppression of an absolute defect in Type IV pilus biogenesis by loss-of-function mutations in pilT, a twitching motility gene in Neisseria gonorrhoeae
Creators: name: Hayes, S.F.
name: Park, H.-S.
name: Wolfgang, M.
name: Koomey, M.
name: Van Putten, J.P.M.
Publisher: name: National Academy of Sciences
Year: 1998

description: Type IV pili of Neisseria gonorrhoeae, the Gram-negative etiologic agent of gonorrhea, facilitate colonization of the human host. Gonococcal PilT, a protein belonging to a large family of molecules sharing a highly conserved nucleotide binding domain motif, has been shown to be dispensable for organelle biogenesis but essential for twitching motility and competence for genetic transformation. Here, we show that the defect in pilus biogenesis resulting from mutations in the pilC gene, encoding a putative pilus-associated adhesin for human tissue, can be suppressed by the absence of functional PilT. These data conclusively demonstrate that PilT influences the Type IV pilus biogenesis pathway and strongly suggest that organelle expression is a dynamic process. In addition, these findings imply that PilT antagonizes the process of organelle biogenesis and provide the basis for a model for how the counteractive roles of PilT and PilC might relate mechanistically to the phenomenon of twitching motility.
Aquesta nafra gloriosa és botiga d’especieria: La contemplación de la Pasión en la Vita Christi de Isabel de Villena. SCRIPTA, Revista internacional de literatura i cultura medieval i moderna, núm. 24 / desembre 2024 / pp. 71 - 87ISSN: 2340-4841· doi:10.7203/SCRIPTA.24.30059.
Creators: name: Peirats Navarro, Anna
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 470514
subject: Literary theory
classificationCode: 470520
subject: Literature in Spanish and Portuguese
classificationCode: 470513
subject: Latin and classical Greek literature

description: Este estudio explora la narrativas contemplativa que rodea al cuerpo sin vida de Cristo en los textos medievales, a partir de la influencia del Arbor vitae crucifixae Iesu Christi (AVCJ) de Ubertino de Casale en la Vita Christi de Francesc Eiximenis y en Isabel de Villena. El artículo examina las variaciones en los elementos estilísticos, las metáforas y los matices temáticos a través de un análisis comparativo de capítulos específicos de la Vita Christi de Isabel de Villena (capítulos 144, 219 y 220). Este análisis revela el impacto de Ubertino en la narrativa de Eiximenis y la amplificación del tono de lamentación en Isabel de Villena, que introduce isotopías únicas, retratando el pecho de Cristo como un armario de curación. El estudio resalta la influencia de Ubertino en la espiritualidad europea, especialmente en la Península Ibérica, dando forma a las expresiones contemplativas que se encuentran en las vitae de Eiximenis e Isabel de Villena.
Sechs Lieder von Göthe : [für eine Singstimme] mit Begleitung des Pianoforte oder der Guitarre ... : 21. Werk
Creators: name: Himmel, Friedrich Heinrich
name: Goethe, Johann Wolfgang von
Publisher: name: A. Kühnel
Year: 1806

description: von F. H. Himmel
description: Druckjahr nach RISM. Davon abweichend 1806 laut Goedeke Bd. 4,3, S. 234
Quantum control and the challenge of non-Hermitian model-building
Creators: name: Znojil, Miloslav
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In the context of traditional quantum-control considerations it is conjectured that one of the promising new strategies of the constructive model building could be sought in a non-stationary upgrade of the formalism of PT-symmetric quantum mechanics. This upgrade is briefly reviewed and characterized by the simultaneous participation of a triplet of Hilbert spaces in the representation of a single quantum system.
description: 15 pp., conference "Quantum Control, Exact or Perturbative, Linear or Nonlinear", CINVESTAV, Mexico City, October 2014, see http://www.fis.cinvestav.mx/mielnik50/?p=9
(101735) John Ash Stooke
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Necrotising otitis externa: The contribution of CT and MR imaging in diagnosis and follow up.
Creators: name: Mellou, Vasiliki
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Ear / Nose / Throat
subject: Emergency
subject: Head and neck
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Complications
subject: Infection
subject: Abscess

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To delineate the extra- and intracranial findings of necrotising otitis externa in order to avoid missing the...
The Enderstruder: An accessible open-source syringe extruder compatible with Ender series 3D printers
Creators: name: Crosby, Cody
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Biomaterials
subject: Materials Science and Engineering
subject: Polymer and Organic Materials
subject: Engineering
subject: Biomedical Engineering and Bioengineering

description: A syringe extruder designed specifically for Ender 3D printers that can be printed and built for less than $60. We have rigorously tested on popular biomaterial inks and pastes. Complete details will be published in an open-access article that has undergone one round of review at this point.
title: Staging solid pancreatic neoplasms: what radiologists should report
Creators: name: Quisiyupanqui, Kathy
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neoplasia
subject: Cancer
subject: Structured reporting
subject: CT
subject: Pancreas
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Describe pancreatic vascular and lymphatic anatomy Describe our dedicated MDCT pancreatic protocol Illustrate imaging criteria essential for optimal staging of pancreatic...
Genetic diversity between mouse strains allows identification of the CC027/GeniUnc strain as an orally reactive model of peanut allergy
Creators: name: Miller, D.R.
name: Fotsch, L.
name: Burks, A.W.
name: Smeekens, J.M.
name: Ye, P.
name: Orgel, K.
name: Guo, R.
name: Kulis, M.D.
name: Pardo-Manuel de Villena, F.
name: Ferris, M.T.
Publisher: name: Mosby Inc.
Year: 2019

description: Background: Improved animal models are needed to understand the genetic and environmental factors that contribute to food allergy. Objective: We sought to assess food allergy phenotypes in a genetically diverse collection of mice. Methods: We selected 16 Collaborative Cross (CC) mouse strains, as well as the classic inbred C57BL/6J, C3H/HeJ, and BALB/cJ strains, for screening. Female mice were sensitized to peanut intragastrically with or without cholera toxin and then challenged with peanut by means of oral gavage or intraperitoneal injection and assessed for anaphylaxis. Peanut-specific immunoglobulins, T-cell cytokines, regulatory T cells, mast cells, and basophils were quantified. Results: Eleven of the 16 CC strains had allergic reactions to intraperitoneal peanut challenge, whereas only CC027/GeniUnc mice reproducibly experienced severe symptoms after oral food challenge (OFC). CC027/GeniUnc, C3H/HeJ, and C57BL/6J mice all mounted a T H 2 response against peanut, leading to production of IL-4 and IgE, but only the CC027/GeniUnc mice reacted to OFC. Orally induced anaphylaxis in CC027/GeniUnc mice was correlated with serum levels of Ara h 2 in circulation but not with allergen-specific IgE or mucosal mast cell protease 1 levels, indicating systemic allergen absorption is important for anaphylaxis through the gastrointestinal tract. Furthermore, CC027/GeniUnc, but not C3H/HeJ or BALB/cJ, mice can be sensitized in the absence of cholera toxin and react on OFC to peanut. Conclusions: We have identified and characterized CC027/GeniUnc mice as a strain that is genetically susceptible to peanut allergy and prone to severe reactions after OFC. More broadly, these findings demonstrate the untapped potential of the CC population in developing novel models for allergy research.
title: Subventricular zone involvement characterized by DTI in glioblastoma
Creators: name: van der Hoorn, Anouk
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Cancer
subject: Imaging sequences
subject: MR-Diffusion/Perfusion
subject: MR
subject: Oncology
subject: Neuroradiology brain

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Glioblastomas (GBM) have a poor prognosis, possibly due to a subpopulation of therapy resistant stem cells within the heterogeneous GBM 1,2 . The subventricular zone (SVZ) harbours the largest population of neural stem cells in the brain 3...
Designing Small Silicon Quantum Dots with Low Reorganization Energy
Creators: name: Zang, Xiaoning
name: Lusk, Mark T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: A first principles, excited state analysis is carried out to identify ways of producing silicon quantum dots with low excitonic reorganization energy. These focus on the general strategy of either reducing or constraining exciton-phonon coupling, and four approaches are explored. The results can be implemented in quantum dot solids to mitigate polaronic effects and increase the lifetime of coherent excitonic superpositions. It is demonstrated that such designs can also be used to alter the shape of the spectral density for reorganization so as to reduce the rates of both decoherence and dissipation. The results suggest that it may be possible to design quantum dot solids that support partially coherent exciton transport.
Pot-pourri : Oeuv. 127 : [für Orchester]
Potpourri
Creators: name: Küffner, Joseph
Publisher: name: Schott fils
Year: 1819

description: Stimmen: Viol. I. & II., Viola, Vc. & Cb., 2 Fl., 2 Ob., 2 Clar., 2 Fag., 2 Hörner (in C), 2 Trp., Posaune (ad. lib.), Pk.
description: Auf der Rückseite des Titelblatts: Preistabelle der musikalischen Instrumente aus der eigenen Fabrik von B. Schott Söhne, Grosherzoglich Hessische Hofmusikhandlung in Mainz
description: Die Herkunft der musikalischen Themen ist in den Stimmen kleingedruckt über den Noten angegeben: Othello ; Elisabetha ; Marcia (di Küffner) ; Barbiere di Siviglia.
description: Auf allen Stimmen verschiedene Stempel, darunter der Rundstempel "Concert-Direction in Basel"
Whole genome sequencing and progress toward full inbreeding of the mouse collaborative cross population
Creators: name: Najarian, M.L.
name: Shorter, J.R.
name: Linnertz, C.L.
name: Bell, T.A.
name: Kashfeen, A.
name: Hock, P.
name: Blanchard, M.
name: Kirchoff, K.E.
name: de Villena, F.P.-M.
name: McMillan, L.
name: Sebastian Sigmon, J.
name: Miller, D.R.
name: Ferris, M.T.
Publisher: name: Genetics Society of America
Year: 2019

description: Two key features of recombinant inbred panels are well-characterized genomes and reproducibility. Here we report on the sequenced genomes of six additional Collaborative Cross (CC) strains and on inbreeding progress of 72 CC strains. We have previously reported on the sequences of 69 CC strains that were publicly available, bringing the total of CC strains with whole genome sequence up to 75. The sequencing of these six CC strains updates the efforts toward inbreeding undertaken by the UNC Systems Genetics Core. The timing reflects our competing mandates to release to the public as many CC strains as possible while achieving an acceptable level of inbreeding. The new six strains have a higher than average founder contribution from non-domesticus strains than the previously released CC strains. Five of the six strains also have high residual heterozygosity (.14%), which may be related to non-domesticus founder contributions. Finally, we report on updated estimates on residual heterozygosity across the entire CC population using a novel, simple and cost effective genotyping platform on three mice from each strain. We observe a reduction in residual heterozygosity across all previously released CC strains. We discuss the optimal use of different genetic resources available for the CC population.
Information Cascades in Feed-based Networks of Users with Limited Attention
Creators: name: Sreenivasan, Sameet
name: Chan, Kevin S.
name: Swami, Ananthram
name: Korniss, Gyorgy
name: Szymanski, Boleslaw
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We build a model of information cascades on feed-based networks, taking into account the finite attention span of users, message generation rates and message forwarding rates. Using this model, we study through simulations, the effect of the extent of user attention on the probability that the cascade becomes viral. In analogy with a branching process, we estimate the branching factor associated with the cascade process for different attention spans and different forwarding probabilities, and demonstrate that beyond a certain attention span, critical forwarding probabilities exist that constitute a threshold after which cascades can become viral. The critical forwarding probabilities have an inverse relationship with the attention span. Next, we develop a semi-analytical approach for our model, that allows us determine the branching factor for given values of message generation rates, message forwarding rates and attention spans. The branching factors obtained using this analytical approach show good agreement with those obtained through simulations. Finally, we analyze an event specific dataset obtained from Twitter, and show that estimated branching factors correlate well with the cascade size distributions associated with distinct hashtags.
description: 8 pages, 5 figures, For IEEE Transactions on Network Science and Engineering (submitted)
Ziņojums par kinoteātru auditorijas patērēšanas paradumiem
Creators: name: Vinogradova, Līga
Publisher: name: Zenodo
Year: 2025
Subjects: Kinoteātru auditorija
Filmu auditorija
Digitālais filmu patēriņš
Latvijas filmas

description: Latvijas Kultūras akadēmijas Kultūras un mākslu institūts īstenojis pētījumu “Kinoteātru auditorija Latvijā: klātienes un digitālā filmu patēriņa prakses”. Pētījums īstenots kā daļa no projekta “Latvijas kultūras ekosistēma kā resurss valsts izturētspējai un ilgtspējai” /CERS (VPP projekts CERS), ko finansē Latvijas Republikas Kultūras ministrija valsts pētījumu programmas “Latvijas kultūra – resurss valsts attīstībai”. VPP projekta CERS 3. darba posms ir tematiski veltīts digitālo tehnoloģiju izpausmēm dažādās  kultūras un radošās ekosistēmas ražošanas cikla fāzēs un to ietekmei uz kultūras patēriņa paradumiem. Šī tematiskā virziena viens no mērķiem ir saistīts ar jaunu zināšanu radīšanu par digitālo tehnoloģiju ietekmi uz iedzīvotāju kultūras patēriņa paradumiem, kultūras satura radīšanas, izplatīšanas un saglabāšanas procesiem. Filmu nozare ir viena no tām, kurā tiek padziļināti pētīta digitālo tehnoloģiju diferencētā ietekme.

Pētījuma mērķis bija noskaidrot, kādi ir filmu patērēšanas paradumi Latvijā un kā digitālās tehnoloģijas tos mainījušas, t.sk., kā mainījusies Latvijas filmu skatīšanās pieredze, fokusējoties uz kinoteātru apmeklētāju klātienes pieredzi. Lai to īstenotu, 2023. gada nogalē tika veikta kinoteātru auditorijas aptauja 9 Latvijas kinoteātros un kino izrādīšanas vietās, aptverot gan Rīgu, gan reģionus. Aptaujas īstenošanā iesaistījās 50 Latvijas Kultūras akadēmijas Kultūras socioloģijas un menedžmenta apakšprogrammas studenti. Ziņojuma autore - pētniece Līga Vinogradova.

Projektu “Latvijas kultūras ekosistēma kā resurss valsts izturētspējai un ilgtspējai” /CERS (Nr. VPP-MM-LKRVA-2023/1-0001) finansē Latvijas Republikas Kultūras ministrija valsts pētījumu programmas “Latvijas kultūra – resurss valsts attīstībai" (2023.–2026.) ietvaros. Valsts pētījumu programmu administrē Latvijas Zinātnes padome.
title: Imaging of pancreatic vascular lesions mimicking tumors: a pictorial review
Creators: name: Ispas, Miruna
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neoplasia
subject: Cancer
subject: Aneurysms
subject: Structured reporting
subject: Education
subject: Diagnostic procedure
subject: MR
subject: CT-Angiography
subject: Catheter arteriography
subject: Vascular
subject: Pancreas
subject: Oncology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To present and illustrate the vascular lesions that mimic pancreatic neoplasm. To discuss the CT, MR and angiographic aspects that differentiate arterial lesions from hypervascular or hemorrhagic pancreatic neoplastic conditions, respectively venous...
Value of peripheral nodes in controlling multilayer networks
Creators: name: Zhang, Yan
name: Garas, Antonios
name: Schweitzer, Frank
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We analyze the controllability of a two-layer network, where driver nodes can be chosen randomly only from one layer. Each layer contains a scale-free network with directed links and the node dynamics depends on the incoming links from other nodes. We combine the in-degree and out-degree values to assign an importance value $w$ to each node, and distinguish between peripheral nodes with low $w$ and central nodes with high $w$. Based on numerical simulations, we find that the controllable part of the network is larger when choosing low $w$ nodes to connect the two layers. The control is as efficient when peripheral nodes are driver nodes as it is for the case of more central nodes. However, if we assume a cost to utilize nodes that is proportional to their overall degree, utilizing peripheral nodes to connect the two layers or to act as driver nodes is not only the most cost-efficient solution, it is also the one that performs best in controlling the two-layer network among the different interconnecting strategies we have tested.
description: 14 pages, 7 figures
(101729) William Stevens
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(101730) Sherrard Augustus Stevens
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Functionally overlapping variants control tuberculosis susceptibility in collaborative cross mice
Creators: name: Hock, P.
name: Ferris, M.T.
name: Baker, R.E.
name: Proulx, M.K.
name: Kiritsy, M.C.
name: Behar, S.M.
name: Sassetti, C.M.
name: Villena, F.P.-M.
name: Lai, R.
name: Bell, T.A.
name: Smith, C.M.
Publisher: name: American Society for Microbiology
Year: 2019

description: Host genetics plays an important role in determining the outcome of Mycobacterium tuberculosis infection. We previously found that Collaborative Cross (CC) mouse strains differ in their susceptibility to M. tuberculosis and that the CC042/ GeniUnc (CC042) strain suffered from a rapidly progressive disease and failed to produce the protective cytokine gamma interferon (IFN-γ) in the lung. Here, we used parallel genetic and immunological approaches to investigate the basis of CC042 mouse susceptibility. Using a population derived from a CC001/Unc (CC001) × CC042 intercross, we mapped four quantitative trait loci (QTL) underlying tuberculosis immunophenotypes (Tip1 to Tip4). These included QTL that were associated with bacterial burden, IFN-γ production following infection, and an IFN-γ-independent mechanism of bacterial control. Further immunological characterization revealed that CC042 animals recruited relatively few antigen-specific T cells to the lung and that these T cells failed to express the integrin alpha L (αL; i.e., CD11a), which contributes to T cell activation and migration. These defects could be explained by a CC042 private variant in the Itgal gene, which encodes CD11a and is found within the Tip2 interval. This 15-bp deletion leads to aberrant mRNA splicing and is predicted to result in a truncated protein product. The ItgalCC042 genotype was associated with all measured disease traits, indicating that this variant is a major determinant of susceptibility in CC042 mice. The combined effect of functionally distinct Tip variants likely explains the profound susceptibility of CC042 mice and highlights the multigenic nature of tuberculosis control in the Collaborative Cross. IMPORTANCE The variable outcome of Mycobacterium tuberculosis infection observed in natural populations is difficult to model in genetically homogeneous small-animal models. The newly developed Collaborative Cross (CC) represents a reproducible panel of genetically diverse mice that display a broad range of phenotypic responses to infection. We explored the genetic basis of this variation, focusing on a CC line that is highly susceptible to M. tuberculosis infection. This study identified multiple quantitative trait loci associated with bacterial control and cytokine production, including one that is caused by a novel loss-of-function mutation in the Itgal gene, which is necessary for T cell recruitment to the infected lung. These studies verify the multigenic control of mycobacterial disease in the CC panel, identify genetic loci controlling diverse aspects of pathogenesis, and highlight the utility of the CC resource.
Study of Senegalese Perceptions of Oil and Gas Discoveries
Creators: name: Kubinec, Robert
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Social and Behavioral Sciences

description: This study uses an online panel to look at how young Senegalese view potential gas and oil discoveries in their country. It also tests for the effect of an experimental treatment involving an entrepreneurship training conducted in the country for a subset of the panel and to see whether this exogenous increase in entrepreneurship is associated with an increase or decrease in perceptions of whether oil/gas discoveries will be beneficial for their careers.
Sechs fröhliche Lieder mit Begleitung des Piano-Forte oder der Guitare
VI fröhliche Lieder mit Begleitung des Pianoforte oder der Gitarre
Creators: name: Huber, Ferdinand Fürchtegott
Publisher: name: Wanaz
Year: 1825

description: Abschied vom Liebchen. "Du muss mer's jo nit übel ufnehma", No. 1 Toms. "Herr Toms ein alter Schiffspatron", No. 2 Wahrsagerlied. "Gieb blancke Schösser, gieb uns Wein", No. 3 <> Tirolerbeub singt. "Gott grüess ech, ihr Beube", No. 4 Treue Liebe. "Frau, sie soll hama gehn", No. 5 <> französische Galanteriekrämer. "Gauf wer da gaufen will", No. 6
title: The BROWNS !! Common Accomplice of Pains, Moans and Groans :Brown Tumors of Primary Hyperparathyroidism Demystified
Creators: name: Vadapalli, Ram Mohan
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Bones
subject: Musculoskeletal bone
subject: Thyroid / Parathyroids
subject: MR
subject: CT
subject: PET-CT
subject: Diagnostic procedure
subject: Laboratory tests
subject: Education
subject: Endocrine disorders
subject: Calcifications / Calculi
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To demonstrate the Multi-Modality Imaging features of Brown tumors of Primary Hyperparathyroidism. To highlight spectrum of associated skeletal manifestations in Primary...
Evaluation of Louisiana's Commercial Vehicle Operations (CVO) – Example of Performance Measurement of Transportation Systems
Creators: name: Abedi, Kwabena
name: Thapa, Raju
name: Codjoe, Julius
name: Gopu, Vijaya
Publisher: name: Journal of Modern Mobility Systems
Year: 2023

description: This study evaluated how Louisiana has met its commercial vehicle operations (CVO) safety goal to reduce commercial vehicle crash rates on its significant freight routes between 2016-2020, with data retrieved from the Louisiana Crash Database. Though the annual frequency of crashes remained relatively constant, the ratio of commercial vehicles saw an increasing trend between 2016 and 2020. This assessment helps to identify freight-related transportation improvement needs in Louisiana and ensures targets and measures are based on data and objective information.
description: Journal of Modern Mobility Systems, Vol. 3 (2022)
A High Reliability Asymptotic Approach for Packet Inter-Delivery Time Optimization in Cyber-Physical Systems
Creators: name: Guo, Xueying
name: Singh, Rahul
name: Kumar, P. R.
name: Niu, Zhisheng
Publisher: name: arXiv
Year: 2015
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences
subject: C.2.1

description: In cyber-physical systems such as automobiles, measurement data from sensor nodes should be delivered to other consumer nodes such as actuators in a regular fashion. But, in practical systems over unreliable media such as wireless, it is a significant challenge to guarantee small enough inter-delivery times for different clients with heterogeneous channel conditions and inter-delivery requirements. In this paper, we design scheduling policies aiming at satisfying the inter-delivery requirements of such clients. We formulate the problem as a risk-sensitive Markov Decision Process (MDP). Although the resulting problem involves an infinite state space, we first prove that there is an equivalent MDP involving only a finite number of states. Then we prove the existence of a stationary optimal policy and establish an algorithm to compute it in a finite number of steps. However, the bane of this and many similar problems is the resulting complexity, and, in an attempt to make fundamental progress, we further propose a new high reliability asymptotic approach. In essence, this approach considers the scenario when the channel failure probabilities for different clients are of the same order, and asymptotically approach zero. We thus proceed to determine the asymptotically optimal policy: in a two-client scenario, we show that the asymptotically optimal policy is a "modified least time-to-go" policy, which is intuitively appealing and easily implementable; in the general multi-client scenario, we are led to an SN policy, and we develop an algorithm of low computational complexity to obtain it. Simulation results show that the resulting policies perform well even in the pre-asymptotic regime with moderate failure probabilities.
Host genetic regulation of immune-based and infectious diseases: Introduction to mammalian genome special issue: genetics of infectious disease
Creators: name: Hood, D.W.
name: Ferris, M.T.
Publisher: name: Springer New York LLC
Year: 2018

description: Infectious disease remains a leading cause of mortality worldwide and includes a wide range of ailments caused by a pathogen, typically a virus, bacterium, fungus or parasite, entering and living in the host body. For many decades, but particularly after the molecular biology revolution brought about by the advent of recombinant DNA techniques in the 1970s, the tenet for an infectious disease biologist was to identify genes on the microbe that might play a role in the pathogenic traits of that organism. By first cloning that gene, mutating it in a defined way, analysing the altered phenotype or function of the mutant strain then restoring the gene function to re-establish pathogenicity and satisfy Koch’s postulates, it was assumed this would lead to a complete understanding of disease. Koch’s postulates however imply that virulence traits reside solely in the microbe and are therefore independent of the host. It is now clear that this aspect of the postulate is erroneous and that indeed the susceptibility of the host is paramount and typically as important, if not more important, than the traits of the microbe in determining the outcome of infection and disease.
Data-Driven Decisions in Transportation – An Assessment of Louisiana's Freight Mobility Goals
Creators: name: Abedi, Kwabena
name: Raju, Thapa
name: Codjoe, Julius
name: Gopu, Vijaya
Publisher: name: Journal of Modern Mobility Systems
Year: 2023

description: This study evaluated how Louisiana has met its commercial vehicle operations (CVO) goals to increase freight mobility and facilitate freight and economic growth on significant freight routes in Louisiana. The performance measures used for this assessment were the Truck Travel Time Reliability (TTTR) Index and vehicle user delay cost for periods between 2016-2020, which were sourced from the National Performance Management Research Data Set (NPMRDS). Louisiana's interstate highway remained reliable with TTTR Index scores of less than 1.50, but some Traffic Messaging Channels (TMC) segments experienced maximum TTTR scores greater than 1.50, which were altogether 15.47% of the interstate highway system, as of 2020. The 15.47% of the interstate highway contributed, on average, 72.34 % of the annual user delay cost between 2016 and 2019 and 62.49% in 2020, which are extremely high considering the length of the interstate system. This paper demonstrates how data can be used to set transportation mobility priorities and also demonstrates how data can be used to identify areas with the greatest need for improvement in a transportation system.
description: Journal of Modern Mobility Systems, Vol. 3 (2022)
(101731) John Moore
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Overview of Evaluating ADFs in the Community
Creators: name: Dasgupta, Nabarun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020
Subjects: Opioids
Drugs
Injections, Intravenous
Epidemiology
Drug addiction
Databases
Chronic pain
Drug abuse
Racism

description: Dr. Nabarun Dasgupta presents as the invited Guest Speaker at the US Food and Drug Administration Advisory Committee on the 10 year evaluation of OxyContin reformulation. Epidemiologic considerations on evaluation of abuse deterrent formulations are presented.

Presented June 10, 2020 at the Joint Meeting of the Drug Safety and Risk Management Advisory Committee (DSARM) and the Anesthetic and Analgesic Drug Products Advisory Committee (AADPAC)

https://www.fda.gov/advisory-committees/advisory-committee-calendar/september-10-11-2020-joint-meeting-drug-safety-and-risk-management-advisory-committee-and-anesthetic
Documentation of time-agnostic-library software
Creators: name: Massari, Arcangelo
Publisher: name: Zenodo
Year: 2022
Subjects: provenance information
change-tracking of RDF data
time-traversal queries
SPARQL
OpenCitations

description: This document is a high-level description of time-agnostic-library, helpful to understand its structure and operation. First, the modules are introduced, along with viable configuration parameters. Then, the user-oriented methods are described.
Die  Augen : "Wohl lieb ich sehr die grüne Flur" : Für eine Singst. mit Gitarre- oder Pianofortebegleitung
Creators: name: Just, Johann August
name: Steingötter, P.
Publisher: name: [s.n.]
Year: 1790

description: J. Just ; Gedicht von P. Steingötter
description: Abschrift (vermutlich später entstanden) vorhanden: Staatsbibliothek zu Berlin, Musikabteilung; Signatur: Mus.ms. 11333
Sociodemographic and Clinical Predictors of Prescription Opioid Use in a Longitudinal Community-Based Cohort Study of Middle-Aged and Older Adults
Creators: name: Nelson, Amanda E.
name: Golightly, Yvonne M.
name: Dasgupta, Nabarun
name: Shiue, Kristin Y.
name: Naumann, Rebecca B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Background: Despite declining opioid prescribing rates in the United States, the annual prevalence of prescription opioid use in adults ≥50 years old is estimated to be 40%, higher than that of younger adults (ages 18-29 years, 36%). As the American population ages, understanding factors that contribute to overall opioid use is a necessary first step in the determination and mitigation of inappropriate prescribing and opioid-related harms.

Objective: Assess predictors of prescription opioid use in an adult population with a high prevalence of chronic pain.

Methods: Data were from a community-based cohort of White and African American adults aged 50-90 years residing in predominantly rural Johnston County, North Carolina. Univariable and multivariable logistic regression models were used to evaluate sociodemographic and clinical factors in non-opioid users (n=795) at baseline (2006-2010) as predictors of opioid use at follow-up (2013-2015). Variables included age, sex, race, obesity (BMI≥30kg/m2), polypharmacy (5+ medications), educational attainment (<12, ≥12 years), employment (unemployed, employed/retired), insurance (uninsured, public, private), Census block group household poverty rate (<12%, 12–24%, ≥25%), depressive symptoms (Center for Epidemiologic Studies Depression Scale ≥16 or depression diagnosis), perceived social support (moderate/poor [<19], strong [≥19]; Strong Ties Measure of Social Support, range 0-20), pain sensitivity (sensitive [<4kg], normal [≥4kg] pressure pain threshold), and pain catastrophizing (high [≥15], moderate/low [<15];  Pain Catastrophizing Helplessness Subscale, range 0-25). 

Results: At follow-up, 13% (n=100) of participants were using prescription opioids. In univariable models, younger age, female sex, obesity, polypharmacy, unemployment, public (vs. private) health insurance, higher poverty rate, depressive symptoms, poorer perceived social support, pain catastrophizing, and elevated pain sensitivity were independently associated (p<0.05) with opioid use. In the multivariable model, younger age (60 vs. 70 years; adjusted odds ratio, 95% confidence interval=2.52, 1.08−5.88), polypharmacy (2.16, 1.24−3.77), high pain catastrophizing (2.17, 1.33−3.56), and depressive symptoms (2.00, 1.17−3.43) remained significant independent predictors. 

Conclusion: The simultaneous assessment of a breadth of clinical and sociodemographic factors identified polypharmacy, pain catastrophizing, and depressive symptoms as modifiable predictors of prescription opioid use. These findings support the incorporation of pharmacological review and behavioral approaches into chronic pain management strategies. Further research is warranted to track changes in these factors as prescription opioid use declines nationwide.
Comparison of Fixed Targets Utilized by State Agencies and the Use of Varying Targets in the Calibration of Traffic Simulation Models
Creators: name: Mamun, Md Mahmud Hasan
name: Amine, Kamar Ali
name: Hadi, Mohammed
name: Morshed, Syed Ahnaf
Publisher: name: Journal of Modern Mobility Systems
Year: 2023

description: Several state departments of transportation have developed simulation guidelines with a strong emphasis on model calibration. These guidelines generally specify fixed targets for each performance measure used in the calibration. However, only a few studies exist that explain the rationale behind and the justification for selecting these calibration targets. In 2019, the Federal Highway Administration (FHWA) released an update to its traffic simulation development methodology, with the concept of calibration targets that vary by segment, time period, and simulated operational scenario depending on the day-to-day variations in the calibrated measure values. As transportation agencies consider the possibility of adopting the FHWA calibration methodology, questions are being raised by the simulation community on how different are the values of the varying targets calculated using the FHWA methodology compared to the existing fixed targets that have been used in the industry for a long time. The purpose of this study is to compare the results from the use of varying calibration targets, as proposed in the methodology of the 2019 guidance, with the fixed targets in the state DOT guidance.
description: Journal of Modern Mobility Systems, Vol. 3 (2022)
(101732) Maria Moore
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Schelmenlieder und andere aus der Liedersammlung eines lustigen Malers : für eine Singstimme mit leichter Begleitung des Piano Forte und der Guitarre: 2. Sammlung, 1. Heft
Creators: name: [s.n.]
Publisher: name: Heerbrandt und Thämel
Year: 1843

description: gesammelt und hg. v. J. A. F[uchs]
description: Eine "1te Lese" (einer zuvor erschienenen Sammlung) von Schelmenliedern (diese nur mit Gitarren-Begl.) ist vorhanden unter Signatur kk XVII 7657
title: Male breast disease: beyond gynecomastia
Creators: name: Romero Laguna, Victoria
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neoplasia
subject: Cancer
subject: Diagnostic procedure
subject: Biopsy
subject: Ultrasound
subject: Mammography
subject: Breast

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Review imaging findings of the most common male breast pathology cases reported in our center and review of...
Sechs Schweizer-Lieder : componirt für eine Singstimme mit Begl. des Pianoforte oder der Guitarre ad lib. und ... Ferd. Lauer, Gesang-Lehrer in Basel ... zugeeignet
Creators: name: Huber, Ferdinand Fürchtegott
name: Kuhn, Gottlieb Jakob
Publisher: name: Joseph Aibl
Year: 1820

description: No. 1 An den frühen Winter. "Ein Botz i thue! g'schau het's nit g'schneit?"
description: No. 2 Mein Liebchen. "I han-es Schätzeli"
description: No. 3 <> Gemsjäger. "I de Flüehne ist mys Lebe"
description: No. 4 <> Kuckuck. "Gott wilche Gugger"
description: No. 5 Für die Knaben von Bern. "Buebe, lueget doch!"
description: No. 6 <> arme Aenneli. "Jä! we-n-i numme rycher wär"
description: Ferd. Huber ; von G. J. Kuhn
description: Ein inhaltlich identischer, aber in Grösse, Titel und Verlag (dort: Rod. Haag et Comp.) abweichender Druck ist in 2 Ex. vorhanden unter kr VI 24 und kk VIII 17:4
Pharmacodynamics of Glyburide, Metformin, and Glyburide/Metformin Combination Therapy in the Treatment of Gestational Diabetes Mellitus
Creators: name: Ahmed, M.S.
name: Clark, S.
name: Hebert, M.F.
name: Shen, D.D.
name: Thummel, K.E.
name: Brown, Z.
name: Ma, X.
name: Brown, L.M.
name: Shireman, L.M.
name: Caritis, S.
name: Tita, A.T.
name: Shuster, D.L.
name: Easterling, T.R.
name: Ren, Z.
name: Haneline, L.S.
name: Flood Nichols, S.K.
name: Haas, D.M.
name: Venkataramanan, R.
name: Manuck, T.A.
name: Quinney, S.K.
Publisher: name: Nature Publishing Group
Year: 2020

description: In gestational diabetes mellitus (GDM), women are unable to compensate for the increased insulin resistance during pregnancy. Data are limited regarding the pharmacodynamic effects of metformin and glyburide during pregnancy. This study characterized insulin sensitivity (SI), β-cell responsivity, and disposition index (DI) in women with GDM utilizing a mixed-meal tolerance test (MMTT) before and during treatment with glyburide monotherapy (GLY, n = 38), metformin monotherapy (MET, n = 34), or GLY and MET combination therapy (COMBO; n = 36). GLY significantly decreased dynamic β-cell responsivity (31%). MET and COMBO significantly increased SI (121% and 83%, respectively). Whereas GLY, MET, and COMBO improved DI, metformin (MET and COMBO) demonstrated a larger increase in DI (P = 0.05) and a larger decrease in MMTT peak glucose concentrations (P = 0.03) than subjects taking only GLY. Maximizing SI with MET followed by increasing β-cell responsivity with GLY or supplementing with insulin might be a more optimal strategy for GDM management than monotherapy.