cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Proteins and protein components for sportspeople: quality control of dietary supplements
Creators: name: Di Stefano, Vita
name: Cicero, Nicola
name: Melilli, Maria Grazia
name: Ganguzza, Enrico
name: Lucarini, Massimo
name: Durazzo, Alessandra
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Quality control of protein supplements intended for a large audience of consumers such as sportspeople is particularly important. A case study on quality control of dietary supplements containing protein and protein components is presented. The objective of the study was to evaluate the conformity of the quantities of amino acids, essential and branched-chain amino acids, declared on the label through measurements with chromatographic analytical tools. 16 sportspeople supplements from different European countries were tested. Analysis of concentrated whey protein highlighted some differences between the label and what was experimentally determined; in these samples some amino acids (6 amino acids out of 19) exceeded the maximum tolerance (>20%) regulated by the European Commission. To a lesser extent, analysis of the other classes revealed amino acid concentrations that exceeded the maximum analytical tolerance percentage. As regards the essential and branched amino acid supplements, it was seen that the declared quantity conforms with that determined experimentally.
sj-docx-3-nnr-10.1177_15459683211017509 – Supplemental material for Effects of Combined and Alone Transcranial Motor Cortex Stimulation and Mirror Therapy in Phantom Limb Pain: A Randomized Factorial Trial
Creators: name: Gunduz, Muhammed Enes
name: Pacheco-Barrios, Kevin
name: Bonin Pinto, Camila
name: Duarte, Dante
name: Vélez, Faddi Ghassan Saleh
name: Gianlorenco, Anna Carolyna Lepesteur
name: Teixeira, Paulo Eduardo Portes
name: Giannoni-Luza, Stefano
name: Crandell, David
name: Battistella, Linamara Rizzo
name: Simis, Marcel
name: Fregni, Felipe
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: Neuroscience

description: Supplemental material, sj-docx-3-nnr-10.1177_15459683211017509 for Effects of Combined and Alone Transcranial Motor Cortex Stimulation and Mirror Therapy in Phantom Limb Pain: A Randomized Factorial Trial by Muhammed Enes Gunduz, Kevin Pacheco-Barrios, Camila Bonin Pinto, Dante Duarte, Faddi Ghassan Saleh Vélez, Anna Carolyna Lepesteur Gianlorenco, Paulo Eduardo Portes Teixeira, Stefano Giannoni-Luza, David Crandell, Linamara Rizzo Battistella, Marcel Simis and Felipe Fregni in Neurorehabilitation and Neural Repair
sj-docx-1-jbx-10.1177_24725552211017500 – Supplemental material for Functional and Pharmacological Comparison of Human and Mouse Na+/Taurocholate Cotransporting Polypeptide (NTCP)
Creators: name: Floerl, Saskia
name: Kuehne, Annett
name: Geyer, Joachim
name: Brockmoeller, Juergen
name: Tzvetkov, Mladen V.
name: Hagos, Yohannes
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-jbx-10.1177_24725552211017500 for Functional and Pharmacological Comparison of Human and Mouse Na+/Taurocholate Cotransporting Polypeptide (NTCP) by Saskia Floerl, Annett Kuehne, Joachim Geyer, Juergen Brockmoeller, Mladen V. Tzvetkov and Yohannes Hagos in SLAS Discovery
Der Ätna und seine Pflanzenwelt
Creators: name: Steinecke, Hilke
name: Schubert, Peter
Publisher: name: Der Palmengarten
Year: 2016

description: Der Ätna auf Sizilien ist der höchste und aktivste Vulkan Europas. Auf kleinem Raum können verschiedene vulkanische Phänomene beobachtet werden. Die Pflanzenwelt am Ätna ist aufgrund der großen Höhenunterschiede sehr abwechslungsreich. Die Vegetationsstufen sowie dort vorkommende Wildpflanzen, darunter auch einige Endemiten des über 3 000 m hohen Vulkans, werden vorgestellt.
description: Der Palmengarten, Bd. 80 Nr. 1 (2016)
Antiproliferative polycyclic polyprenylated acylphloroglucinols from Garcinia paucinervis
Creators: name: Jia, Cui-Cui
name: Xue, Jing-Jing
name: Li, Zhan-Lin
name: Li, Da-Hong
name: Hua, Hui-Ming
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Bioassay-guided isolation of the stems of Garcinia paucinervis led to one new adamantane-type polycyclic polyprenylated acylphloroglucinols (PPAPs), (-)-garpauvinin A (1), and four known analogues (2–5). The structure and absolute configuration of 1 was established via spectroscopic techniques and ECD method. All the isolates displayed moderate antiproliferative activity against HL-60, PC-3 and Caco-2 human cancer cell lines with IC50 values ranging from 0.81 to 19.92 μM, and exhibited low toxicity on WPMY-1 normal human cells, showing selectivity between normal and malignant prostate cells. The biosynthetic pathways of the isolated PPAPs were proposed.
Additional file 3 of Identification of CDK gene family and functional analysis of CqCDK15 under drought and salt stress in quinoa
Creators: name: Wang, Wangtian
name: Liu, Wenyu
name: Wang, Baoqiang
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Supplementary Material 3
Identification of volatile compounds and their bioactivities from unpolar fraction of Alpinia oxyphylla Miq. and mining key genes of nootkatone biosynthesis
Creators: name: Busayo, Fapetu Kemi
name: Yang, Jin-Ling
name: Ding, Xu-Po
name: Wang, Ya-Li
name: Gai, Cui-Juan
name: Wu, Fei
name: Dai, Hao-Fu
name: Mei, Wen-Li
name: Chen, Hui-Qin
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Hematology

description: In this study, analysis of the chemical constituents and bioactivities of the unpolar fractions [petroleum ether (PE) and chloroform (C)] of fruits and leaves of Alpinia oxyphylla Miq. were carried out, as well as the bioactivities of the main compounds nootkatone and valencene. From PE and C fractions of the fruits, and PE fraction of the leaves, 95.80%, 59.30%, and 82.11% of the chemical constituents respectively were identified by GC-MS. Among these identified compounds, nootkatone was the main compound in all of three fractions, while valencene was the second main compound in the PE fractions of the fruits and leaves. The bioactivities results showed that all of the fractions and the major compound nootkatone showed tyrosinase inhibitory, as well as inhibitory effect on NO production in LPS-stimulated RAW264.7 cells. While valencene only presented inhibitory activity on NO production in RAW264.7 cells. The critical genes involved in nootkatone biosynthesis in A. oxyphylla were identified from the public transcriptome datasets, and protein sequences were preliminarily analyzed. Our studies develop the usage of the unpolar fractions of A. oxyphylla, especially its leaves as the waste during its production, and meanwhile provide the gene resources for nootkatone biosynthesis.
sj-pdf-1-prq-10.1177_10659129211017991 – Supplemental material for Institutional Development and Participation on House Roll-Call Votes, 1819–1921
Creators: name: Baughman, John
name: Nokken, Timothy P.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-pdf-1-prq-10.1177_10659129211017991 for Institutional Development and Participation on House Roll-Call Votes, 1819–1921 by John Baughman and Timothy P. Nokken in Political Research Quarterly
Sarre Grave 238
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: A spear-head vertically placed, as in the last grave, in the upper soil; an arrangement evidently designed, but for what object is not apparent. Three beads [KAS 441], a small bronze buckle, iron rivets, and a peculiar object in iron [KAS 643], about six inches and a half long; the remains of keys or spears, much corroded, a foreign shell, the Cyprea Arabica [KAS 475], some broken mussel-shells, and a very small fragment of deep violet glass [KAS 484?].All these small objects appear to have been placed in a box, and exhibited more or less the action of fire. This grave yielded also pieces of iron, like links of a cable-patterned chain, and some bronze rings. Its incongruous contents might indicate a double interment, the beads and shell being the relics of a woman, the spear-head of a man.
sj-pdf-1-jrs-10.1177_01410768211014048 - Supplemental material for Patient-reported outcome measurement: a bridge between health and social care?
Creators: name: Hughes, Sarah
name: Aiyegbusi, Olalekan Lee
name: Lasserson, Daniel
name: Collis, Philip
name: Glasby, Jon
name: Calvert, Melanie
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, sj-pdf-1-jrs-10.1177_01410768211014048 for Patient-reported outcome measurement: a bridge between health and social care? by Sarah Hughes, Olalekan Lee Aiyegbusi, Daniel Lasserson, Philip Collis, Jon Glasby and Melanie Calvert in Journal of the Royal Society of Medicine
Encapsulation of propolis extract in ovalbumin protein particles: characterization and in vitro digestion
Creators: name: Jansen-Alves, Cristina
name: Victoria, Francine N.
name: Borges, Caroline D.
name: Zambiazi, Rui C.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Space Science
Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The encapsulation of propolis has shown promising results for the protection of bioactive compounds, local and gradual release and masking the astringent taste. Ovoalbumin is a protein of animal origin found in large amounts in egg whites, which has good properties as a wall material for particles.The objective of this study was to microencapsulate propolis by spray drying. The best condition for microencapsulation was achieved with 4% ovalbumin at 120 °C, where there was the greatest encapsulation efficiency (88.20%) and spherical shape. However, the increase of ovalbumin concentration resulted lower yields (< 52%). As for the scanning electron microscopy (SEM), the increase of ovalbumin concentration caused an increase of the size with average diameter and formation of spherical microcapsules. The phenolic compounds were already released in the gastric fluid condition (stomach).
sj-pdf-1-pic-10.1177_0954406221998399 - Supplemental material for Synthesis method for planetary gear trains without using rotation graphs
Creators: name: Cui, Rongjiang
name: Ye, Zhizheng
name: Sun, Liang
name: Zheng, Guanghui
name: Wu, Chuanyu
Publisher: name: SAGE Journals
Year: 2021
Subjects: Engineering not elsewhere classified

description: Supplemental material, sj-pdf-1-pic-10.1177_0954406221998399 for Synthesis method for planetary gear trains without using rotation graphs by Rongjiang Cui, Zhizheng Ye, Liang Sun, Guanghui Zheng and Chuanyu Wu in Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science
Additional file 1 of Early warning signals for stock market crashes: empirical and analytical insights utilizing nonlinear methods
Creators: name: Song, Shijia
name: Li, Handong
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Appendix. This refers to a multi-page table. For more information, please see the word file named “appendix”. (DOCX 21 kB)
Wheat Data Interoperability Guidelines, Ontologies and User Cases
Creators: name: Yeumo, Esther Dzalé
name: Fulss, Richard
name: Alaux, Michael
name: Aubin, Sophie
name: Arnaud, Elizabeth
name: Baumann, Ute
name: Cooper, Laurel
name: Davey, Robert
name: Marie-Angélique Laporte
name: Larmande, Pierre
name: Letellier, Thomas
name: Pommier, Cyril
name: Vassilis Protonotarios
name: Shrestha, Rosemary
name: Subirats, Imma
name: Aravind Venkatesan
name: Whan, Alex
Publisher: name: Research Data Alliance
Year: 2016

description: The International Wheat Initiative (http://www.wheatinitiative.org) has identified the easy access and interoperability of all wheat related data as a top priority for the wheat research community. An important goal is to make the best use of existing genetic, genomic, and phenotypic data in fundamental and applied wheat science. Hence, data interoperability has become a priority in this community, given the ever-growing data deluge coming from improvements in technologies and numeric methods for DNA (Deoxyribonucleic acid) and RNA (Ribonucleic acid) sequencing, high throughput genotyping and phenotyping, high throughput imaging and satellite monitoring.

The Wheat Data Interoperability working group (WDI-WG) was created in 2014 as a Research Data Alliance (RDA, http://rd-alliance.org) working group under the umbrella of Wheat Information System (WheatIS, http://wheatis.org/) expert working group, which is endorsed by the International Wheat Initiative to build an international information system for genetic, genomic, and phenomic data. The primary mission of the WDI-WG is to provide a common framework for describing and representing data with respect to existing open standards. The WDI-WG is formed by data and information practitioners and scientists from different organizations and countries. The standpoint of the WDI-WG was to avoid the creation of new standards. Therefore, the WDI-WG started by surveying the practices of the wheat research community, then converged and agreed on specific recommendations. The proposed recommendations have been endorsed by the RDA and the WheatIS expert working group.
Phellinus igniarius polysaccharides induced mitochondrial apoptosis of hepatic carcinoma by enhancing reactive oxygen species-mediated AKT/p53 signalling pathways
Creators: name: Jin, Xin
name: Chen, Ninggang
name: Zhang, Tingsu
name: Fang, Qing
name: Hu, Ying
name: Tao, Jin
name: Lin, Hangjuan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Plant Biology
subject: Virology

description: Phellinus igniarius (PI) has various kinds of biological activities, such as antitumour activities, and polysaccharides are one of its main components. In this study, polysaccharides from PI (PIP) were prepared, purified, analysed for their structure and investigated for their antitumour activity and mechanism in vitro. PIP consists of 12138 kDa of carbohydrates containing 90.5 ± 1.6% neutral carbohydrates. PIP consists of glucose, galactose, mannose, xylose, D-fructose, L-guluronic acid, glucosamine hydrochloride, rhamnose, arabinose and D-mannoturonic acid. PIP can significantly inhibit HepG2 cell proliferation, induce cell apoptosis and also inhibited migration and invasion in a concentration-dependent manner. PIP increased reactive oxygen species (ROS), increased the expression of p53, and induced cytochrome c release into the cytoplasm to activate caspase-3. PIP is a promising potential candidate for the therapeutic treatment of hepatic carcinoma via the ROS-mediated mitochondrial apoptosis pathway.
Sarre Grave 240
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: Burnt or decayed wood in some quantity. By the left shoulder, a spear-head [KAS 920] of unusual shape, and its socket, both vertically placed, as in Nos. CCXXXVII and CCXXXVIII. Also a large knife, and a black earthen vessel at the foot, too fragile to be preserved.
Chemical constituents isolated from Hosta ensata and their anti-inflammatory activities
Creators: name: Chen, Hongping
name: Yang, Li
name: Zhong, Weihong
name: Wang, Kexin
name: Zhong, Guoyue
name: He, Junwei
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Virology

description: A new phenol derivative, hostaphenol A (1), along with 16 known ones (2–17) were isolated from an ethanolic extract of the whole plants of Hosta ensata F. Maek. Their structures were elucidated by HRMS and NMR data as well as comparison with those reported in literature. The report of the first cyclopeptide and compounds 5, 6, 8, 10, 12–15, and 17 in the Asparagaceae family. Compound 2, as well as compounds 3, 4, 7, 9, 11, and 16 were reported for the first time from the Hosta genus and this plant, respectively. All compounds significantly reduced nitric oxide (NO) production at a concentration of 40 μM with no toxicity in RAW 264.7 cells stimulated by lipopolysaccharide. Among them, compounds 2–5 (40 μM) exerted obvious NO inhibitory activities, and their inhibition rate was exceeded 50%.
Alkaloids from the stems of Fissistigma maclurei Merr. inhibit the proliferation of synoviocytes
Creators: name: Liang, Mu-Tao
name: Zhang, Xiao-Zheng
name: Chen, Zi-Hao
name: Fu, Chuan-Shan
name: Li, Duo-Jiang
name: Chen, Guo-Ze
name: Yi, Ji-Ling
name: Zhou, Xue-Ming
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Two new aporphine-derived alkaloids, aporaloids C and D (1 and 2), along with eight known biogenetically related alkaloids (3–10) were isolated from the stems of Fissistigma maclurei Merr. Their structures were elucidated by detailed analysis of NMR, HRESIMS, MS, IR, UV and Optical rotations data. Compounds 1 and 2 represent a rare example of N-methylol aporphine-derived alkaloids from natural sources. The inhibitory effect of all compounds on the proliferation of primary synovial cells was evaluated. Compound 3 showed potent inhibitory effect on the proliferation of synoviocytes with an IC50 value of 4.8 μM. Compounds 1, 2, 6–9 and 10 exhibited moderate inhibitory activity on synoviocytes, with IC50 values of 36.8, 37.1, 31.2 μM, 32.5, 36.3, 36.8 and 18.2 μM, respectively.
Supplemental Material, sj-pdf-1-tct-10.1177_15330338211016373 - Prediction of Radiation Pneumonitis With Machine Learning in Stage III Lung Cancer: A Pilot Study
Creators: name: Yakar, Melek
name: Durmus Etiz
name: Metintas, Muzaffer
name: Guntulu Ak
name: Ozer Celik
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 110320 Radiology and Organ Imaging
subject: Biochemistry

description: Supplemental Material, sj-pdf-1-tct-10.1177_15330338211016373 for Prediction of Radiation Pneumonitis With Machine Learning in Stage III Lung Cancer: A Pilot Study by Melek Yakar, Durmus Etiz, Muzaffer Metintas, Guntulu Ak and Ozer Celik in Technology in Cancer Research & Treatment
Additional file 1 of Synaptic retrograde regulation of the PKA-induced SNAP-25 and Synapsin-1 phosphorylation
Creators: name: Polishchuk, Aleksandra
name: Cilleros-Mañé, Víctor
name: Just-Borràs, Laia
name: Balanyà-Segura, Marta
name: Vandellòs Pont, Genís
name: Silvera Simón, Carolina
name: Tomàs, Marta
name: Garcia, Neus
name: Tomàs, Josep
name: Lanuza, Maria A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology

description: Additional file 1. Original blots. The western blotting pictures were cropped from the original pictures with different conditions but not modified. Each dot in the bars of the graphs is representing the mean result of one animal.
Evaluating the application of an arabinoxylan-rich fraction from brewers’ spent grain as a release modifier of drugs
Creators: name: García-Curiel, Laura
name: Pérez-Flores, Jesús Guadalupe
name: Contreras-López, Elizabeth
name: Pérez-Escalante, Emmanuel
name: Paz-Samaniego, Rita
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Cell Biology
Pharmacology
Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: This study evaluated the possible use of a fraction of brewers’ spent grain rich in arabinoxylans (BSG-AX) as an excipient that modifies the release of class III drugs (Biopharmaceutics Classification System), by determining the release profile of metformin hydrochloride (MH), in a water medium. The cumulative percentage of MH release showed the best linear fit when modeled with the cumulative distribution function (CDF) of the Weibull distribution (R2 = 0.993 ± 0.001). According to the Korsmeyer-Peppas model, the first stage of MH release is regulated by a super case-II transport mechanism controlled by the expansion and relaxation of BSG-AX. Finally, with the Hixson-Crowell model, a release rate (kHC) of 0.350 ± 0.026 h−13 was obtained (R2 = 0.996 ± 0.007). BSG-AX constitutes a suitable material for producing prolonged drug release vehicles; however, additional research is required to provide a better encapsulation of the active ingredients to ensure their optimal applicability and performance.
sj-pdf-1-aan-10.1177_02184923211018589 - Supplemental material for Transcatheter aortic valve implantation in low-risk patients: A case of rational over exuberance. The time is not now
Creators: name: Navaratnarajah, Manoraj
name: Luthra, Suvitesh
name: Ohri, Sunil
Publisher: name: SAGE Journals
Year: 2021
Subjects: Cardiology

description: Supplemental material, sj-pdf-1-aan-10.1177_02184923211018589 for Transcatheter aortic valve implantation in low-risk patients: A case of rational over exuberance. The time is not now by Manoraj Navaratnarajah, Suvitesh Luthra and Sunil Ohri in Asian Cardiovascular & Thoracic Annals
Rank und schlank: Schlangengurke
Creators: name: Markwirth, Jennifer
Publisher: name: Der Palmengarten
Year: 2015

description: Die Schlangenhaargurke (Trichosanthes cucumerina) ist ein rankendes Kürbisgewächs aus Indien. Biologie, Morphologie und Verwendung der Früchte werden vorgestellt. Die Art ist auch im Tropicarium zu sehen. Es werden kurze Hinweise zur Kultur gegeben.
description: Der Palmengarten, Bd. 79 Nr. 2 (2015)
Antifouling activity and biodegradable potential of the bioactive metabolites isolated from mangrove Avicennia officinalis L
Creators: name: Ramasubburayan, Ramasamy
name: Prakash, Santhiyagu
name: Pitchiah, Sivaperumal
name: Dhanraj, Ganapathy
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The present study explores the antifouling potentials of ethanol extract of mangrove Avicennia officinalis. Results of antibacterial activity inferred that extract had strongly inhibited the growth of fouling bacterial strains with significant differences in halos (9-16 mm) and showed minimal bacteriostatic (12.5–100 µg ml−1) and bactericidal (25-200µg ml−1) values. It had also strenuously suppressed fouling microalgae with appreciable MIC (12.5 and 50 µg ml−1). The extract had also effectively deterred settlement of larvae of Balanus amphitrite and byssal thread of mussel Perna indica with lower EC50 (11.67 and 37.43 µg ml−1) and higher LC50 (257.33 and 817 µg ml−1) values. Further 100% recuperation of mussels from toxicity assay and therapeutic ratio of >20 substantiated its non-toxicity. GC-MS profile of bioassay guided fraction showed four (M1-M4) major bioactive metabolites. In silico biodegradability study revealed that metabolites M1 (Pentanoic acid, 5-methoxy-, phenyl ester) and M3 (Benzaldehyde, methyl-) have rapid biodegradation rates and eco-friendly in nature.
Cytotoxicity sesquiterpenoids from the leaves of Datura stramonium L.
Creators: name: Pan, Juan
name: Liu, Yan
name: Wang, Ao-Fei
name: Wu, Jia-Tong
name: Yang, Rui
name: Guan, Wei
name: Algradi, Adnan Mohammed
name: Kuang, Hai-Xue
name: Yang, Bing-You
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Four new sesquiterpenoids, dstramonins A-D (1–4), and one new natural product (5), together with three known compounds (6–8), were isolated from the leaves of Datura stramonium L. The structures of new compounds were elucidated by extensive spectroscopic analysis and comparison with the literature. The cytotoxicity of isolates against LN229 cells was assessed and compounds 2–4, and 7 displayed cytotoxic activity with IC50 values ranging from 8.03 to 13.83 μM.
Additional file 1 of Analysis of the association between urinary glyphosate exposure and fatty liver index: a study for US adults
Creators: name: Han, Kexing
name: Gao, Long
name: Xu, Honghai
name: Li, Jiali
name: Han, Lianxiu
name: Shen, Jiapei
name: Sun, Weijie
name: Gao, Yufeng
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1
Biological and phytochemical potential of Baccharis trimera (Less.) DC leaf extract on swine clinical isolates
Creators: name: Brusamarello, Micheli Negri
name: Brusamarello, Antonio Pedro
name: da Cunha, Mário Antônio Alves
name: Busso, Cleverson
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Virology

description: Phytochemical studies have shown extracts obtained from the aerial parts of Baccharis trimera (Less.) DC has antioxidant and antimicrobial activities and the potential to treat some diseases. This study investigated the phenolic compounds, antioxidant and antimicrobial activity, and phytochemical potential of B. trimera leaf extract obtained by decoction on ATCC standard bacterial strains and 23 swine clinical isolates. Water was used as an extraction solvent based on the principles of green chemistry and at a low cost. The decoction process resulted in an extract rich in phenolic compounds and a high capacity for scavenging DPPH and ABTS radicals. Phytochemical analysis of aqueous extracts was performed using HPLC-DAD, and high concentrations of chlorogenic, ferulic, caffeic, and cinnamic phenolic acids were found. Antimicrobial activity was observed against gram-negative bacteria. B. trimera aqueous extract may be a promising low-cost agent for prophylactic treatment against swine enteropathogens and contribute to reducing production costs.
Additional file 2 of Analysis of the association between urinary glyphosate exposure and fatty liver index: a study for US adults
Creators: name: Han, Kexing
name: Gao, Long
name: Xu, Honghai
name: Li, Jiali
name: Han, Lianxiu
name: Shen, Jiapei
name: Sun, Weijie
name: Gao, Yufeng
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 2
Submerged cultivation of Nigrospora sp. in batch and fed-batch modes for microbial oil production
Creators: name: Tonato, Denise
name: Brun, Thiarles
name: Luft, Luciana
name: dos Santos, Maicon Sérgio Nascimento
name: Drumm, Fernanda Caroline
name: Grassi, Patrícia
name: Georgin, Jordana
name: Kuhn, Raquel C.
name: Zabot, Giovani L.
name: Mazutti, Marcio A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Microbial lipids are a valuable source of potential biofuels and essential polyunsaturated fatty acids. The optimization of the fermentation conditions is a strategy that affects the total lipid concentration. The genus Nigrospora sp. has been the target of investigations based on its potential bioherbicidal action. Therefore, this study developed a strategy to maximize the biomass concentration and lipid accumulation by Nigrospora sp. in submerged fermentation. Different media compositions and process variables were investigated in shaken flasks and bioreactor in batch and fed-batch modes. Maximum biomass concentration and lipid accumulations were 40.17 g/L and 21.32 wt% in the bioreactor, which was 2.1 and 5.4 times higher than the same condition in shaken flasks, respectively. This study presents relevant information to the production of fungal lipids since few investigations are exploring the fed-batch strategy to increase the yield of fungi lipids, as well as few studies investigating Nigrospora sp. to produce lipids.
Synthesised thymoquinone-oxime induces cytotoxicity, genotoxicity and apoptosis in hepatocellular cancer cells: in vitro study
Creators: name: Guler, Eray Metin
name: Bozali, Kubra
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Hepatocellular carcinoma is the most common primary malignant tumor of the liver, and its incidence is increasing worldwide. There is a need to develop new therapeutic strategies to treat the disease. In this study, we synthesised the oxime derivative of thymoquinone and investigated cytotoxicity, genotoxicity, and apoptosis in hepatocellular cancer cells. The synthesised thymoquinone-oxime structure was confirmed by NMR. After incubating the hepatocellular cancer cell line for 24 h, the cytotoxicity ATP by luminometric, intracellular reactive oxygen species, and intracellular calcium by fluorometric. The mitochondrial membrane potential was determined by flow cytometry. DNA damage by alkaline single-cell gel electrophoresis, and apoptosis damage by acridine orange/ethidium bromide double dye method. Concentrations of thymoquinone-oxime statistically increased cytotoxicity, intracellular reactive oxygen species, intracellular calcium, apoptosis, and DNA damage in a concentration-dependent manner. Mitochondrial membrane potential and glutathione levels are also decreased. These findings show that thymoquinone-oxime has an anti-tumor effect on hepatocellular carcinoma cells. Among many herbs, Black seed (Nigella sativa) belonging to the Ranunculaceae family has been recognised worldwide as one of the most valuable nutrient-rich herbsThere is no relevant data on the effect of the newly synthesised oxime derivative of TQ (TQ-ox) in cancer cells HEP-G2A new TQ derivative has a higher anti-tumor effect on hepatocellular carcinoma Among many herbs, Black seed (Nigella sativa) belonging to the Ranunculaceae family has been recognised worldwide as one of the most valuable nutrient-rich herbs There is no relevant data on the effect of the newly synthesised oxime derivative of TQ (TQ-ox) in cancer cells HEP-G2 A new TQ derivative has a higher anti-tumor effect on hepatocellular carcinoma
Cytotoxic and molecular evaluation of spilanthol obtained from Acmella oleracea (L.) R. K. Jansen (jambu) in human gastric cancer cells
Creators: name: da S. Pinheiro, Mayra Suelen
name: Moysés, Daniele A.
name: Galucio, Natasha C. R.
name: Santos, Willian Oliveira
name: Pina, Jeferson R. Souza
name: Oliveira, Luana C.
name: Silva, Simone Yasue S.
name: da Cruz Silva, Sebastião
name: Frazão, Nilton Ferreira
name: Marinho, Patrícia Santana B.
name: Novais, Andrea L. F.
name: Khayat, André S.
name: do Rosário Marinho, Andrey Moacir
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Molecular Biology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Acmella oleracea (L.) is a plant popularly known as jambu in the Brazilian Amazon. This species has several biological properties, such as anaesthetic, antioxidant and anti-inflammatory activities, among others. However, there is limited information on its anticancer activity. In this context, this study aims to evaluate the effects of the hydroethanolic extract of jambu and its active compound (spilanthol) on gastric cancer cells. Hydroethanolic jambu inflorescence extract was obtained, and spilanthol was isolated by HPLC. Biological cytotoxicity assays were determined using MTT tests. In addition, an in silico study using molecular docking evaluated the inhibitory properties of spilanthol against JAK1 and JAK2 proteins. The results showed that the hydroethanolic extract and the isolated compound spilanthol exhibited cytotoxicity against cancer cells. Molecular docking revealed that spilanthol has inhibitory potential for JAK1 and JAK2 proteins. Thus, extract of jambu and spilanthol can be a possible candidate for the treatment of gastric carcinoma.
Additional file 1 of Perceived barriers and facilitators to infection prevention and control in Dutch residential care facilities for people with intellectual and developmental disabilities: a cross-sectional study
Creators: name: Houben, Famke
name: den Heijer, Casper DJ
name: Dukers-Muijrers, Nicole HTM
name: Smeets-Peels, Claudia
name: Hoebe, Christian JPA
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
sj-pdf-1-tou-10.1177_14687976211019906 – Supplemental material for Unsettling the aesthetics of air travel through participatory tourist photography
Creators: name: Barry, Kaya
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 120599 Urban and Regional Planning not elsewhere classified
subject: FOS: Social and economic geography

description: Supplemental material, sj-pdf-1-tou-10.1177_14687976211019906 for Unsettling the aesthetics of air travel through participatory tourist photography by Kaya Barry in Tourist Studies
sj-docx-2-men-10.1177_10608265211018803 – Supplemental material for Is Traditional Masculinity Still Valued? Men’s Perceptions of How Different Reference Groups Value Traditional Masculinity Norms
Creators: name: Iacoviello, Vincenzo
name: Valsecchi, Giulia
name: Berent, Jacques
name: Borinca, Islam
name: Falomir-Pichastor, Juan M.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Gender studies
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-2-men-10.1177_10608265211018803 for Is Traditional Masculinity Still Valued? Men’s Perceptions of How Different Reference Groups Value Traditional Masculinity Norms by Vincenzo Iacoviello, Giulia Valsecchi, Jacques Berent, Islam Borinca and Juan M. Falomir-Pichastor in The Journal of Men's Studies
Sarre Grave 250
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: CCL. A red earthen vessel [KAS 245], lying on its side in a recess at the feet. Three shield-studs and a broken umbo [AS 3]; a sword [KAS 825], in a wooden or leathern sheath, imperfect; two spear-heads, one broken (an old fracture), and a knife.
Aphid Cerosipha forbesi control using Piper macedoi Yunck essential oil in strawberry crop
Creators: name: dos Santos, Ana Terra Bravim
name: Dian, Vanessa Sessa
name: Parreira, Luciana Alves
name: Lourenço, Maicon Pierre
name: Zanuncio, José Salazar
name: de Jesus, Ester Gonçalves
name: Santos, Mario Ferreira Conceição
name: Menini, Luciano
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Strawberry is a food rich in bioactive compounds with great antioxidant potential. However, due to the high incidence of pests that affect crop cultivation, phytosanitary management still lacks control methods for agroecological cultivation. Thus, the present research aimed to evaluate the chemical composition and the potential of the essential oil of the leaves of Piper macedoi in the control of Cerosipha forbesi in laboratory and semi-field conditions. The concentration of essential oil in the leaves of P. macedoi that showed the highest mortality was 2.0 ml/L of oil, with a mortality above 91% under laboratory conditions. A mortality rate of 80% for all concentrations tested was observed after 24 h in all conditions tested. Thus, using essential oil from the leaf of P. macedoi can be a highly viable strategy in managing the aphid C. forbesi since it showed high mortality rates with small doses of oil.
Additional file 1 of Expressions of pandemic fatigue on digital platforms: a thematic analysis of sentiment and narratives for infodemic insights
Creators: name: White, Becky K.
name: Ishizumi, Atsuyoshi
name: Lavery, Lucy
name: Wright, Amy
name: Foley, Tom
name: O’Neill, Rhys
name: Rambaud, Kimberly
name: Sreenath, Ravi Shankar
name: Salvi, Cristiana
name: Takahashi, Ryoko
name: D’Agostino, Marcelo
name: Nguyen, Tim
name: Briand, Sylvie
name: Purnat, Tina D.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1: Appendix 1. Keywords and phrases for search strategy.
Phytochemical profiling and antioxidant activity of Linum trigynum
Creators: name: Mouna, Ryma
name: Kabouche, Zahia
name: Bensouici, Chawki
name: Broisat, Alexis
name: Ahmed, Abdalwahab
name: Ghezzi, Catherine
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: In this study, the total phenolic and flavonoid contents (TPC and TFC), secondary metabolite composition (LC-HRMS/MS analyses) and antioxidant potential (DPPH, ABTS, GOR, CUPRAC, and phenanthroline assays) of Linum trigynum L. (LT) extracts were determined. Our results showed for the first time that the extracts (PE, CHCl3, AcOEt, and n-BuOH) of LT exert antioxidant activity. The AcOEt and n-BuOH extracts were the most antioxidant compared to the standards, and had a higher amount of TPC (323.51 ± 0.62; 229.98 ± 6.80 µg GAE/mL) and TFC (183.75 ± 1.17 and 157.50 ± 1.77 µg QE/mL), resectively. The high antioxidant properties of these extracts may be due to their major compounds (phenolic compounds) detected by LC-HRMS/MS analyses including flavonoids (40 compounds) and phenolic acids and derivatives (18 and 19 compounds, respectively). AcOEt and n-BuOH extracts of LT can be used as an excellent source of antioxidant phytochemicals to prevent or treat various diseases.
Additional file 1 of The link between glycemic control measures and eye microvascular complications in a clinical cohort of type 2 diabetes with microRNA-223-3p signature
Creators: name: Da’as, Sahar I.
name: Ahmed, Ikhlak
name: Hasan, Waseem H.
name: Abdelrahman, Doua A.
name: Aliyev, Elbay
name: Nisar, Sabah
name: Bhat, Ajaz Ahmad
name: Joglekar, Mugdha V.
name: Hardikar, Anandwardhan A.
name: Fakhro, Khalid A.
name: Akil, Ammira S. Al-Shabeeb
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Additional file 1: Figure S1. Conservation of miRNA 223. Figure S2. Zebrafish miR-223 functional model survival rate. Figure S3. Zebrafish miR-223 mimic expression. Table S1. Demographic data and clinical characteristics of study subjects. Table S2. Primers used for gene expression evaluation in zebrafish.
sj-pdf-2-msc-10.1177_09691413211018253 - Supplemental material for Cost-effectiveness analysis of lung cancer screening with low-dose computed tomography in an Iranian high-risk population
Creators: name: Esmaeili, Mansur Haji
name: Seyednejad, Farshad
name: Mahboub-Ahari, Alireza
name: Ameri, Hossein
name: Abdollahzad, Hadi
name: Safaei, Naser
name: Alinezhad, Farbod
name: Yousefi, Mahmood
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111402 Obstetrics and Gynaecology
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-2-msc-10.1177_09691413211018253 for Cost-effectiveness analysis of lung cancer screening with low-dose computed tomography in an Iranian high-risk population by Mansur Haji Esmaeili, Farshad Seyednejad, Alireza Mahboub-Ahari, Hossein Ameri, Hadi Abdollahzad, Naser Safaei, Farbod Alinezhad and Mahmood Yousefi in Journal of Medical Screening
Potential inhibitory effect of geraniol isolated from lemongrass (Cymbopogon commutatus Stapf) on tilmicosin-induced oxidative stress in cardiac tissue
Creators: name: Ammar, Rebai Ben
name: Alamer, Sarah Abdulaziz
name: Mohamed, Maged Elsayed
name: Althumairy, Duaa
name: Al-Ramadan, Saeed Y.
name: Alfwuaires, Manal
name: Younis, Nancy S.
name: Althnaian, Thnaian A.
name: H., Ibrahim R. I.
name: Rajendran, Peramaiyan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: An experimental study has been conducted to investigate the efficacy of geraniol (GNL) isolated from lemomgrass in protecting against cardiac toxicity induced by tilmicosin (TIL) in albino mice. Compared to TIL-treated mice, those supplemented with GNL had a thicker left ventricular wall and a smaller ventricular cavity. Studies of TIL animals treated with GNL showed that their cardiomyocytes had markedly changed in diameter and volume, along with a reduction in numerical density. After TIL induction, animals showed a significant increase in the protein expression of TGF-β1, TNF-α, nuclear factor kappa B (NF-kB), by 81.81, 73.75 and 66.67%, respectively, and hypertrophy marker proteins ANP, BNP, and calcineurin with respective percentages of 40, 33.34 and 42.34%. Interestingly, GNL significantly decreased the TGF-β1, TNF-α, NF-kB, ANP, BNP, and calcineurin levels by 60.94, 65.13, 52.37, 49.73, 44.18 and 36.84%, respectively. As observed from histopathology and Masson’s trichrome staining, supplementation with GNL could rescue TIL-induced cardiac hypertrophy. According to these results, GNL may protect the heart by reducing hypertrophy in mice and modulating biomarkers of fibrosis and apoptosis.
Additional file 2 of Intracranial efficacy and safety of furmonertinib 160 mg with or without anti-angiogenic agent in advanced NSCLC patients with BM/LM as salvage therapy
Creators: name: Xu, Ziyi
name: Hao, Xuezhi
name: Wang, Qi
name: Yang, Ke
name: Li, Junling
name: Xing, Puyuan
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Supplementary Figure 1. Hazard ratio of PFS in the BM cohort with different characteristics who received furmonertinib 160mg with or without anti-angiogenic agent as salvage therapy using univariate analysis. A hazard ratio less than 1 implies a lower risk of disease progression or death in group 1 than in group 2. Supplementary Figure 2. Hazard ratio of PFS in the LM cohort with different characteristics who received furmonertinib 160mg with or without anti-angiogenic agent as salvage therapy using univariate analysis. A hazard ratio less than 1 implies a lower risk of disease progression or death in group 1 than in group 2.