cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Impact of efforts to prevent maternal deaths due to obstetric hemorrhage on trends in epidemiology and management of severe postpartum hemorrhage in Japan: a nationwide retrospective study
Creators: name: Ueda, Akihiko
name: Nakakita, Baku
name: Chigusa, Yoshitsugu
name: Mogami, Haruta
name: Ohtera, Shosuke
name: Kato, Genta
name: Mandai, Masaki
name: Kondoh, Eiji
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Supplementary Table 1. The International Classification of Diseases (Tenth Revision) andcorresponding MHLW codes for etiologies of PPH. Supplementary Table 2. Etiologiesof patients with severe postpartum hemorrhage by maternal age. Supplementary Table 3. Etiologiesof severe PPH cases that underwent hemostatic procedures between 2013 and 2018. Supplementary Table 4. Etiologiesof severe PPH cases by the type of treatment facilities. Supplementary Table 5. The frequencyof blood transfusion and hemostatic treatments by the type of treatmentfacilities.
title: Running injuries: an epidemiological study
Creators: name: Listabarth, Stephan
name: Benca, Emir
name: Florian Flock, Florian
name: Pablik, Elonore
name: Walzer, Sonja
name: Dorotka, Ronald
name: Windhager, Reinhard
name: Ziai, Pejman
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: Running
subject: Injuries
subject: Epidemiology
subject: Sports Medicine
subject: 610 Medical sciences; Medicine

description: Objectives: Running is one of the most popular physical activities worldwide. Besides its obvious benefits, it is associated with injuries (running related injuries or RRI). It remains unclear which key factors act predisposing or protective of RRI. It is very likely that the aetiology of RRI is complex[for full text, please go to the a.m. URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2018)
Genomic basis for skin phenotype and cold adaptation in the extinct Steller’s sea cow
Creators: name: Le Duc, Diana
name: Velluva, Akhil
name: Cassatt-Johnstone, Molly
name: Olsen, Remi-Andre
name: Baleka, Sina
name: Lin, Chen-Ching
name: Lemke, Johannes R.
name: Southon, John R.
name: Burdin, Alexander
name: Hildebrandt, Thomas B.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Steller’s sea cow
subject: skin phenotype
subject: cold adaptation
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Steller’s sea cow, an extinct sirenian and one of the largest Quaternary mammals, was described by Georg Steller in 1741 and eradicated by humans within 27 years. Here, we complement Steller’s descriptions with paleogenomic data from 12 individuals. We identified convergent evolution between Steller’s sea cow and cetaceans but not extant sirenians, suggesting a role of several genes in adaptation to cold aquatic (or marine) environments. Among these are inactivations of lipoxygenase genes, which in humans and mouse models cause ichthyosis, a skin disease characterized by a thick, hyperkeratotic epidermis that recapitulates Steller’s sea cows’ reportedly bark-like skin. We also found that Steller’s sea cows’ abundance was continuously declining for tens of thousands of years before their description, implying that environmental changes also contributed to their extinction.
PCSK9 Inhibitors in a German Single-Center Clinical Practice: Real-World Treatment of Patients at High Cardiovascular Risk Over 68 Weeks
Creators: name: Hollstein, Tim
name: Kassner, Ursula
name: Grenkowitz, Thomas
name: Schumann, Friederike
name: Bobbert, Thomas
name: Steinhagen-Thiessen, Elisabeth
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: cardiovascular diseases
subject: PCSK9 inhibitors
subject: lipid-lowering therapies
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Aims: Several the use of proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) for patients at high/very high cardiovascular risk who are inadequately treated with maximally tolerated lipid-lowering therapies (LLTs). Objectives: We assessed the effectiveness and safety of the PCSK9i alirocumab and evolocumab in a single-center clinical practice for up to 68 weeks. Methods: In this prospective, open-label study conducted in Germany, 635 enrolled patients were treated with alirocumab [75 or 150 mg every 2 weeks (Q2W)] or evolocumab (140 mg Q2W) according to European Society of Cardiology/European Atherosclerosis Society guidelines (low-density lipoprotein cholesterol [LDL-C] > 1.81/2.59 mmol/L (70/100 mg/dL), depending on cardiovascular risk]. Investigators were able to adjust LLTs, including PCSK9i, according to their own clinical judgment. The primary effectiveness endpoint was LDL-C reduction from baseline to week 68. Results: At baseline, approximately 50% of patients were statin intolerant, and approximately 90% reported a history of cardiovascular disease. LDL-C reductions remained generally unchanged from weeks 4 to 68 in each treatment group. At week 68, LDL-C mean percentage changes from baseline were - 41.7% (alirocumab 75 mg Q2W), - 53.7% (alirocumab 150 mg Q2W), and - 54.1% (evolocumab 140 mg Q2W). LDL-C reduction was 7.1% greater in patients receiving statins than in those not receiving statins because of statin intolerance (P < 0.0001). PCSK9i consistently improved levels of other lipoproteins throughout. Overall, 47.1% of patients reported adverse events at week 68. Conclusions: Consistent with clinical trial findings, alirocumab and evolocumab improved lipid levels in a real-world setting in patients with high baseline LDL-C levels despite receiving maximally tolerated LLTs. PCSK9i were generally well-tolerated.
Acute lymphoblastic leukemia displays a distinct highly methylated genome
Creators: name: Hetzel, Sara
name: Mattei, Alexandra L.
name: Kretzmer, Helene
name: Qu, Chunxu
name: Chen, Xiang
name: Fan, Yiping
name: Wu, Gang
name: Roberts, Kathryn G.
name: Luger, Selina
name: Meissner, Alexander
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Cancer
subject: Cancer epigenetics
subject: Cancer genomics
subject: Haematological cancer
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: DNA methylation is tightly regulated during development and is stably maintained in healthy cells. In contrast, cancer cells are commonly characterized by a global loss of DNA methylation co-occurring with CpG island hypermethylation. In acute lymphoblastic leukemia (ALL), the commonest childhood cancer, perturbations of CpG methylation have been reported to be associated with genetic disease subtype and outcome, but data from large cohorts at a genome-wide scale are lacking. Here, we performed whole-genome bisulfite sequencing across ALL subtypes, leukemia cell lines and healthy hematopoietic cells, and show that unlike most cancers, ALL samples exhibit CpG island hypermethylation but minimal global loss of methylation. This was most pronounced in T cell ALL and accompanied by an exceptionally broad range of hypermethylation of CpG islands between patients, which is influenced by TET2 and DNMT3B. These findings demonstrate that ALL is characterized by an unusually highly methylated genome and provide further insights into the non-canonical regulation of methylation in cancer.
Herichthys Baird and Girard 1854
Creators: name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
name: Piller, Kyle R.
name: Chakrabarty, Prosanta
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Cichlidae
Herichthys

description: Genus Herichthys Baird and Girard 1854
(Fig. 6)
Inclusive species. H. cyanoguttatus (type species), H. carpintis, H. deppii, H. minckleyi, H. tamasopoensis, H. tepehua, H. teporatus.
Diagnosis. Herichthys is diagnosed by six to seven vertical bars (often at the posterior of the body) with dark blotches below the upper lateral line. Breeding coloration includes a darkened color ventrally on lateral portions of the body with light- or gray-colored markings on the dorsum. The anteriormost teeth in the upper jaw are spatulate, chisel-like, or bicuspid.
Distribution. Rivers of the Atlantic slope of Mexico and the Río Grande drainage of the United States (Texas) and Mexico.
Comments. Our diagnostic characteristics for Herichthys follow De la Maza-Beningnos et al. (2015) based on their recent revision of the group. Herichthys (before it was divided into Herichthys and Nosferatu) was largely diagnosed by the shared color pattern of bars and/or blotches along the lateral sides of the body, and a breeding coloration consisting of a dark ventral portion and a lighter dorsal portion of the body (Oldfield et al. 2015). As recognized here, following De la Maza-Beningnos et al. (2015), the traditional breeding coloration characters delineate these clades, but with slight differences in the extent of coloration between Herichthys and Nosferatu. Our molecular analysis supports the monophyly of Herichthys and its sister relationship with Nosferatu. At the species level within Herichthys, none of the species in the genus are recovered as monophyletic in De la Maza- Benignos et al. (2015). Status and validity of the species within this genus are in need of further study.
Material examined. H. carpintis, UMMZ 234903 [n=10, Mexico: Río Paunuco]; H. cyanoguttata, UMMZ 92313 [n=4, Mexico: Arroyo Marmolejo], FMNH 4435 [n=9, Mexico: Río Camacho]; H. minckleyi, UMMZ 130395 [n=15 (Paratypes), Mexico: Cuatro Cienegas], UMMZ 211734 [n=15, Mexico: Cuatro Cienegas]; H. tamasopoensis, UMMZ 193513 [n=15, Mexico: Río Tamasopo], UMMZ 196699 [n=15, Mexico: Río Panuco].
description: Published as part of Mcmahan, Caleb D., Matamoros, Wilfredo A., Piller, Kyle R. & Chakrabarty, Prosanta, 2015, Taxonomy and systematics of the herichthyins (Cichlidae: Tribe Heroini), with the description of eight new Middle American Genera, pp. 211-234 in Zootaxa 3999 (2) on pages 219-220, DOI: 10.11646/zootaxa.3999.2.3, http://zenodo.org/record/237045
Additional file 1 of Autologous skin-derived neural precursor cell therapy reverses canine Alzheimer dementia-like syndrome in a proof of concept veterinary trial
Creators: name: Valenzuela, Michael
name: Duncan, T.
name: Abey, A.
name: Johnson, A.
name: Boulamatsis, C.
name: Dalton, M. A.
name: Jacobson, E.
name: Brunel, L.
name: Child, G.
name: Simpson, D.
name: Buckland, M.
name: Lowe, A.
name: Siette, J.
name: Westbrook, F.
name: McGreevy, P.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Supplementary Materials.
Nosferatu De
Creators: name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
name: Piller, Kyle R.
name: Chakrabarty, Prosanta
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Cichlidae
Nosferatu

description: Genus Nosferatu De la Maza-Benignos et al. 2015
(Fig. 7)
Inclusive species. N. pame (type species), N. bartoni, N. labridens, N. molango, N. pantostictus, N. pratinus, N. steindachneri.
Diagnosis. Teeth in anteriormost portion of upper jaw conical and unicuspid, relatively elongate body. Lateral markings variable and irregular (stripe or blotches). Breeding coloration dark ventrally (similar to Herichthys), but often not to the extent of members of Herichthys in covering most of the body.
Distribution. Rivers of the Atlantic slope of Mexico.
Comments. De la Maza-Benignos et al. (2015), in a revision of the Herichthys, described the genus Nosferatu. Herein we recover Nosferatu as monophyletic; however, we lack sequence data for the new species N. tepehua described in De la Maza-Benignos et al. (2015). As with Herichthys, many of the species of Nosferatu were not recovered as monophyletic in the phylogenetic analysis of mitochondrial sequences by De la Maza-Benignos et al. (2015). Species limits and diversity, as well as interspecific relationships, within Nosferatu remain unresolved.
Material examined. N. bartoni, UMMZ 172193 [n=15, Mexico: Río Verde], UMMZ 202972 [n=15, Mexico: Río Panuco]; N. labridens, UMMZ 203203 [n=10, Mexico: Río Tamesi], UMMZ 203205 [n=2, Mexico: Río Tamesi]; N. pantostictus, UMMZ 170951 [n=8, Mexico: Río Tamesi], UMMZ 209431 [n=2, Mexico: Río Tamesi]; N. steindachneri, FMNH 62682 [n=43, Mexico: Río Sabinas], UMMZ 193514 [n=22, Mexico: Río Tamasopo].
description: Published as part of Mcmahan, Caleb D., Matamoros, Wilfredo A., Piller, Kyle R. & Chakrabarty, Prosanta, 2015, Taxonomy and systematics of the herichthyins (Cichlidae: Tribe Heroini), with the description of eight new Middle American Genera, pp. 211-234 in Zootaxa 3999 (2) on page 220, DOI: 10.11646/zootaxa.3999.2.3, http://zenodo.org/record/237045
Automated Laser-Transfer Synthesis of High-Density Microarrays for Infectious Disease Screening
Creators: name: Paris, Grigori
name: Heidepriem, Jasmin
name: Tsouka, Alexandra
name: Liu, Yuxin
name: Mattes, Daniela S.
name: Pinzón Martín, Sandra
name: Dallabernardina, Pietro
name: Mende, Marco
name: Lindner, Celina
name: Seeberger, Peter H.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: high-throughput
subject: laser-induced forward transfer
subject: peptides
subject: Schiff base fluorophores
subject: solid phase synthesis
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Laser-induced forward transfer (LIFT) is a rapid laser-patterning technique for high-throughput combinatorial synthesis directly on glass slides. A lack of automation and precision limits LIFT applications to simple proof-of-concept syntheses of fewer than 100 compounds. Here, an automated synthesis instrument is reported that combines laser transfer and robotics for parallel synthesis in a microarray format with up to 10 000 individual reactions cm−2. An optimized pipeline for amide bond formation is the basis for preparing complex peptide microarrays with thousands of different sequences in high yield with high reproducibility. The resulting peptide arrays are of higher quality than commercial peptide arrays. More than 4800 15-residue peptides resembling the entire Ebola virus proteome on a microarray are synthesized to study the antibody response of an Ebola virus infection survivor. Known and unknown epitopes that serve now as a basis for Ebola diagnostic development are identified. The versatility and precision of the synthesizer is demonstrated by in situ synthesis of fluorescent molecules via Schiff base reaction and multi-step patterning of precisely definable amounts of fluorophores. This automated laser transfer synthesis approach opens new avenues for high-throughput chemical synthesis and biological screening.
Wilhelm Fiedler (1832-1912) an die Neue Zürcher Zeitung, Briefkonzept
Creators: name: Fiedler, Wilhelm
Publisher: name: [s.n.]
Year: 1878

description: Briefkonzept.
Entwurf zur Einsendung an die Redaktion der NZZ, später erschienen in Nr. 85, 1878
description: ETH-Bibliothek
A Valveless Pulsatile Pump for Heart Failure with Preserved Ejection Fraction: Hemo- and Fluid Dynamic Feasibility
Creators: name: Escher, Andreas
name: Choi, Young
name: Callaghan, Fraser
name: Thamsen, Bente
name: Kertzscher, Ulrich
name: Schweiger, Martin
name: Hübler, Michael
name: Granegger, Marcus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: 4D-flow MRI
subject: CFD
subject: Ex vivo
subject: Hybrid mock loop
subject: In silico
subject: In vitro
subject: Isolated porcine heart model
subject: Single cannula
subject: Stagnation
subject: Washout
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Treatment of heart failure with preserved ejection fraction (HFpEF) remains a major unmet medical need. An implantable valveless pulsatile pump with a single cannula-the CoPulse pump-may provide beneficial hemodynamic support for select HFpEF patients when connected to the failing ventricle. We aimed to demonstrate hemodynamic efficacy and hemocompatible design feasibility for this novel assist device. The hemodynamic effect of the pump was investigated with an in vitro circulatory mock loop and an ex vivo isolated porcine heart model. The hydraulic design was optimized using computational fluid dynamics (CFD), and validated by 4D-flow magnetic resonance imaging (MRI). The pump reduced left atrial pressure (> 27%) and increased cardiac output (> 14%) in vitro. Ex vivo experiments revealed elevated total stroke volume at increased end-systolic volume during pump support. Asymmetric cannula positioning indicated superior washout, decreased stagnation (8.06 mm2 vs. 31.42 mm2), and marginal blood trauma potential with moderate shear stresses (< 24 Pa) in silico. Good agreement in flow velocities was evident among CFD and 4D-flow MRI data (r > 0.76). The CoPulse pump proved hemodynamically effective. Hemocompatibility metrics were comparable to those of a previously reported, typical pulsatile pump with two cannulae. The encouraging in vitro, ex vivo, and hemocompatibility results substantiate further development of the CoPulse pump.
Additional file 2 of Autologous skin-derived neural precursor cell therapy reverses canine Alzheimer dementia-like syndrome in a proof of concept veterinary trial
Creators: name: Valenzuela, Michael
name: Duncan, T.
name: Abey, A.
name: Johnson, A.
name: Boulamatsis, C.
name: Dalton, M. A.
name: Jacobson, E.
name: Brunel, L.
name: Child, G.
name: Simpson, D.
name: Buckland, M.
name: Lowe, A.
name: Siette, J.
name: Westbrook, F.
name: McGreevy, P.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. Supplementary Protocols.
Theraps Gunther 1862
Creators: name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
name: Piller, Kyle R.
name: Chakrabarty, Prosanta
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Cichlidae
Theraps

description: Genus Theraps Günther 1862
(Fig. 8)
Inclusive species. T. irregularis (type species), T. godmanni, T. intermedius, T. microphthalmus, T. nourissati.
Diagnosis. Species of the genus Theraps are all elongate (T. irregularis) to moderately elongate (other species) cichlids occurring in lotic riverine systems. All species possess bodies that are longer than deep, versus deepbodied as in Vieja and Maskaheros. The mouth is small and subterminal, with the upper jaw extending over the lower jaw (more so in T. irregularis than in congeners). Spots are present on the dorsal, anal, and caudal fins. This genus is most similar to Paraneetroplus and Rheoheros gen. nov. Species of Paraneetroplus possess lower jaw teeth oriented anteriorly, versus dorsally in Theraps. Species of Rheoheros gen. nov. possess a freckled appearance across the body, versus the absence of this characteristic in Theraps.
Distribution. Atlantic slope rivers of Mexico, Belize, and Guatemala, to lowland tributaries of the Río Motagua drainage in Honduras (only T. microphthalmus).
Comments. Theraps has always included riverine, elongate to moderately elongate cichlids (Allgayer 1989; Günther 1862). Phylogenetic relationships recovered in the present study, as well as the corroboration of Matamoros et al. (2015), support this traditional habitat association, but with some restrictions on the inclusion of other riverine species in this genus (e.g., species of Rheoheros). Thus, this riverine ecology and elongate body shape have evolved more than once within the herichthyin cichlids. The Honduran endemic ‘ C.’ wesseli was described as a member of Theraps but is not recovered as part of this clade or genus in any phylogenetic study to date. We continue to recognize the species as a member of ‘ Cichlasoma’ (incertae sedis) pending a systematic and taxonomic treatment of this species.
Material examined. T. godmanni, BMNH 1864.1.26.49-50 [n=2 (Syntypes), Guatemala: Río Cahabon], UMMZ 146113 [n=22, Guatemala: Río Cahabon]; T. intermedium, UMMZ 143744 [n=12, Guatemala: Río La Pasion], UMMZ 161764 [n=24, Mexico: Río Usumacinta]; T. microphthalmus, UMMZ 179910 [n=5, Guatemala: Río Motagua], UMMZ 190569 [n=15, Guatemala: Río Motagua], LSUMZ 15614 [n=8, Honduras: Río Motagua]; T. nourissati, MNHN 1989-0583 [n=1 (Holotype), Mexico: Chiapas], MNHN 1989-0583 [n=2 (Paratypes), Mexico: Chiapas].
description: Published as part of Mcmahan, Caleb D., Matamoros, Wilfredo A., Piller, Kyle R. & Chakrabarty, Prosanta, 2015, Taxonomy and systematics of the herichthyins (Cichlidae: Tribe Heroini), with the description of eight new Middle American Genera, pp. 211-234 in Zootaxa 3999 (2) on page 221, DOI: 10.11646/zootaxa.3999.2.3, http://zenodo.org/record/237045
Explorative analysis of a score predicting the therapy response of patients with metastatic, castration resistant prostate cancer undergoing radioligand therapy with 177 Lu-labeled prostate-specific membrane antigen
Creators: name: Huang, Kai
name: Schatka, Imke
name: Rogasch, Julian M. M.
name: Lindquist, Randall L.
name: De Santis, Maria
name: Erber, Barbara
name: Radojewski, Piotr
name: Brenner, Winfried
name: Amthauer, Holger
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Predictive score
subject: Radioligand therapy
subject: Metastatic castration-resistant prostate cancer
subject: Lu-177 PSMA
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objective: Up to 60% of patients with metastatic, castration-resistant prostate cancer (mCRPC) treated with 177Lu prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) achieves a partial biochemical response with a decrease of > 50% in prostate-specific antigen (PSA) levels. The remaining fractions, however, do not respond to RLT. The aim of this explorative analysis was to identify pre-therapeutic factors for the prediction of response. Methods: 46 patients [age = 68 years (50-87)] with mCRPC who consecutively underwent RLT with 177Lu PSMA [median applied activity = 6 GBq (2.9-6.2)] were included and analysed retrospectively. The association of different clinical and laboratory factors and parameters from pre-therapeutic 68Ga PSMA positron emission tomography (PET) with the outcome of RLT was tested (Fisher's test). Outcome was defined as PSA changes 8 weeks after second RLT [partial response (PR), PSA decrease > 50%; progressive disease (PD), PSA increase ≥ 25%; stable disease (SD), others]. Significant predictive factors were combined in a predictive score. Results: 30% showed a post-treatment PR (median 73% PSA decrease), 35% SD (median 17% PSA decrease) and 35% PD (median 42% PSA increase). Significant predictors for PD were alkaline phosphatase (ALP) > 135 U/l (p = 0.002), PSA > 200 ng/ml (p = 0.036), and maximum standardized uptake value (SUVmax) of the "hottest lesion" in pre-therapeutic PET < 45 (p = 0.005). The predictive score including PSA, ALP and SUVmax could separate 2 distinct groups of patients: ≤ 2 predictive factors (19% PD) and 3 predictive factors (90% PD). Conclusion: The presented predictive score allowed a pre-therapeutic estimate of the expected response to 2 cycles of RLT. As our study was retrospective, prospective trials are needed for validation.
Megasorex gigas
Creators: name: Mittermeier, Russell A.
name: Wilson, Don E.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Soricomorpha
Soricidae
Megasorex
Megasorex gigas

description: 152. Mexican Shrew Megasorex gigas French: Musaraigne géante / German: Mexikanische Wistenspitzmaus / Spanish: Musarana gigante de Mexico Other common names: Merriam's Desert Shrew, Mexican Giant Shrew Taxonomy. Notiosorex gigas Merriam, 1897, “ Mts. at Milpillas, near San Sebastian, Jalisco, Mexico.” Restricted by L.. N. Carraway in 2007 to “latitude 22-12°N, longitude 104-11°W.” This species is monotypic. Distribution. N Nayarit S to W Oaxaca (W Mexico). Descriptive notes. Head-body 69-84 mm, tail 32-49 mm, ear 9-15 mm, hindfoot 12-16 mm; weight 9-12 g. The Mexican Shrew is relatively large. Dorsum is light grayish brown, with barely lighter venter. There are reports of some specimens with white spots on back either at shoulder or rear. Feet are stout, with long gripping finger and dark pinkish. Tail is ratlike and relatively bare, being somewhat longer than sympatric species (40-60% of head-body length) and dark blackish brown. Snout is long and dark pinkish, with dark brown median ridge extending to tip. Ears are longer than most sympatric species and similar in color to dorsal pelage; eyes are small. Like its relatives in Notiosorex, there is no pigmentation on the teeth; M,, M,, and P, have straight edges; molars are tightly put together, bulky, and unexcavated posteriorly. There are three unicuspids, with third being one-half the size of second. Dental formulais 13/2, C1/0,P 1/1, M 3/8=28. Habitat. Primarily highland wet scrubland, pine-oak forests, cloud forests, and coffee fields at elevations of 80-1800 m. Mexican Shrews are rarely captured in lowland regions and are often associated with damp areas under logs and rocks with dense vegetation. Food and Feeding. No information. Breeding. A lactating Mexican Shrew was captured in June 1964. Activity patterns. Mexican Shrews have been captured day and night but are most often captured at night. Movements, Home range and Social organization. No information. Status and Conservation. Classified as Least Concern on The IUCN Red List. Although the Mexican Shrew may be resilient and is found in multiple protected areas including Chamela-Cuixmala Biosphere Reserve, it might be threatened by habitat loss from urban and agricultural expansion, especially because 68% of its habitat had been developed and was unsuitable by 2005. It is listed as threatened in Mexico, mostly because of its rarity and few specimens. Bibliography. Armstrong & Jones (1972a), Carraway (2007), Ceballos & Mendoza (2014), Davis (1957).
description: Published as part of Russell A. Mittermeier & Don E. Wilson, 2018, Soricidae, pp. 332-551 in Handbook of the Mammals of the World – Volume 8 Insectivores, Sloths and Colugos, Barcelona :Lynx Edicions on page 449, DOI: 10.5281/zenodo.6870843
Transition of laser-induced terahertz spin currents from torque- to conduction-electron-mediated transport
Creators: name: Jiménez-Cavero, Pilar
name: Gueckstock, Oliver
name: Nádvorník, Lukáš
name: Lucas, Irene
name: Seifert, Tom S.
name: Wolf, Martin
name: Rouzegar, Reza
name: Brouwer, Piet W.
name: Becker, Sven
name: Kampfrath, Tobias
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Magnetism
subject: Spin caloritronics
subject: Spin current
subject: Spintronics
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Spin transport is crucial for future spintronic devices operating at bandwidths up to the terahertz range. In F|N thin-film stacks made of a ferromagnetic/ferrimagnetic layer F and a normal-metal layer N, spin transport is mediated by (1) spin-polarized conduction electrons and/or (2) torque between electron spins. To identify a crossover from (1) to (2), we study laser-driven spin currents in F|Pt stacks where F consists of model materials with different degrees of electrical conductivity. For the magnetic insulators yttrium iron garnet, gadolinium iron garnet (GIG) and γ−Fe2O3, identical dynamics is observed. It arises from the terahertz interfacial spin Seebeck effect (SSE), is fully determined by the relaxation of the electrons in the metal layer, and provides a rough estimate of the spin-mixing conductance of the GIG/Pt and γ−Fe2O3/Pt interfaces. Remarkably, in the half-metallic ferrimagnet Fe3O4 (magnetite), our measurements reveal two spin-current components with opposite direction. The slower, positive component exhibits SSE dynamics and is assigned to torque-type magnon excitation of the A- and B-spin sublattices of Fe3O4. The faster, negative component arises from the pyrospintronic effect and can consistently be assigned to ultrafast demagnetization of minority-spin hopping electrons. This observation supports the magneto-electronic model of Fe3O4. In general, our results provide a route to the contact-free separation of torque- and conduction-electron-mediated spin currents.
Engineered Thin Films By Pulsed Laser Deposition For Thermionic Applications
Creators: name: Bellucci Alessandro
name: Girolami Marco
name: Mastellone Matteo
name: Stefano, Orlando
name: Mezzi Alessio
name: Kaciulis Saulius
name: Trucchi Daniele Maria
Publisher: name: Zenodo
Year: 2017
Subjects: Thermionic emission
TIPV
Pulsed Laser Deposition
Work function
Borides
Nitrides

description: Thin films of borides (LaB6 and CeB6) and nitrides (CNx and AlN) were grown by ns (ArF, 193 nm) pulsed laser deposition (PLD) on refractory substrates selected by considering the thermal matching with the thin films in terms of thermal expansion and thermal and electric conductivities. Thin layers of these materials can act as efficient electron emitters for thermionic cathodes operating at high temperature (up to 2000 °C) due to their low work function, typically  < 3 eV, and the high melting point. The electron emission was found to depend strongly on the film thicknesses. The physical properties of the thin films were optimized by varying the deposition temperature of the substrates, the target-to-substrate, the atmosphere (vacuum  or Ar gas flow). X-ray spectroscopy (XPS) was used to investigate the properties of the deposited thin films. Ultraviolet PhotoSpectroscopy (UPS) and thermionic emission measurements were performed to evaluate the work functions of the emitting layers deposited on the selected substrates.
Quantum computational advantage via high-dimensional Gaussian boson sampling
Creators: name: Deshpande, Abhinav
name: Mehta, Arthur
name: Vincent, Trevor
name: Quesada, Nicolás
name: Hinsche, Marcel
name: Ioannou, Marios
name: Madsen, Lars
name: Lavoie, Jonathan
name: Eisert, Jens
name: Hangleiter, Dominik
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: quantum computational advantage
subject: Gaussian boson sampling
subject: photonics
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Photonics is a promising platform for demonstrating a quantum computational advantage (QCA) by outperforming the most powerful classical supercomputers on a well-defined computational task. Despite this promise, existing proposals and demonstrations face challenges. Experimentally, current implementations of Gaussian boson sampling (GBS) lack programmability or have prohibitive loss rates. Theoretically, there is a comparative lack of rigorous evidence for the classical hardness of GBS. In this work, we make progress in improving both the theoretical evidence and experimental prospects. We provide evidence for the hardness of GBS, comparable to the strongest theoretical proposals for QCA. We also propose a QCA architecture we call high-dimensional GBS, which is programmable and can be implemented with low loss using few optical components. We show that particular algorithms for simulating GBS are outperformed by high-dimensional GBS experiments at modest system sizes. This work thus opens the path to demonstrating QCA with programmable photonic processors.
title: Einfluss des Tragens einer Schulterorthese auf die körperliche Aktivität im Alltag – eine Akzelerometer-basierte Studie
Creators: name: Böttcher, Annika
name: Grabowski, Monika
name: Gosheger, Georg
name: Rickert, Carolin
name: Schorn, Dominik
name: Schneider, Kristian
name: Klingebiel, Sebastian
name: Liem, Dennis
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: Schulterorthese
subject: Alltagsaktivität
subject: Immobilisierung
subject: Rehabilitation
subject: 610 Medical sciences; Medicine

description: Fragestellung: Der negative Einfluss sedentären Verhaltens auf den allgemeinen Gesundheitszustand findet bei orthopädischen/unfallchirurgischen Behandlungen oftmals wenig Beachtung. Bei der orthetischen Versorgung der unteren Extremität ist eine Verminderung der Alltagsaktivität[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2018)
Unbiased post-error slowing in interference tasks: A confound and a simple solution
Creators: name: Derrfuss, Jan
name: Danielmeier, Claudia
name: Klein, Tilmann A.
name: Fischer, Adrian G.
name: Ullsperger, Markus
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Performance monitoring
subject: Action errors
subject: Post-error adaptations
subject: Cognitive control
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: We typically slow down after committing an error, an effect termed post-error slowing (PES). Traditionally, PES has been calculated by subtracting post-correct from post-error RTs. Dutilh et al. (Journal of Mathematical Psychology, 56(3), 208-216, 2012), however, showed PES values calculated in this way are potentially biased. Therefore, they proposed to compute robust PES scores by subtracting pre-error RTs from post-error RTs. Based on data from a large-scale study using the flanker task, we show that both traditional and robust PES estimates can be biased. The source of the bias are differential imbalances in the percentage of congruent vs. incongruent post-correct, pre-error, and post-error trials. Specifically, we found that post-correct, pre-error, and post-error trials were more likely to be congruent than incongruent, with the size of the imbalance depending on the trial type as well as the length of the response-stimulus interval (RSI). In our study, for trials preceded by a 700-ms RSI, the percentages of congruent trials were 62% for post-correct trials, 66% for pre-error trials, and 56% for post-error trials. Relative to unbiased estimates, these imbalances inflated traditional PES estimates by 37% (9 ms) and robust PES estimates by 42% (16 ms) when individual-participant means were calculated. When individual-participant medians were calculated, the biases were even more pronounced (40% and 50% inflation, respectively). To obtain unbiased PES scores for interference tasks, we propose to compute unweighted individual-participant means by initially calculating mean RTs for congruent and incongruent trials separately, before averaging congruent and incongruent mean RTs to calculate means for post-correct, pre-error and post-error trials.
Mobile News Learning — Investigating Political Knowledge Gains in a Social Media Newsfeed with Mobile Eye Tracking
Creators: name: Ohme, Jakob
name: Maslowska, Ewa H.
name: Mothes, Cornelia
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Political knowledge
subject: mobile media
subject: social media
subject: news frames
subject: mobile eye tracking
subject: smartphones
subject: 300 Sozialwissenschaften::320 Politikwissenschaft::320 Politikwissenschaft

description: This study investigates whether knowledge gains from news post exposure are different when scrolling through a social media newsfeed on a smartphone compared to a desktop PC. While prior research has mostly focused on new platforms people receive news on (e.g., social media) for political learning, first indications exist that device modality (i.e. exposure on smartphone vs. desktop PC) itself alters news exposure patterns. With the help of mobile eye-tracking, this study investigates cognitive processes that enable learning from exposure among a student sample (n = 122). We extend prior research on the mediating role of attention for learning by investigating whether different frames of political news posts can attenuate this indirect relationship. The study uses a 2 × 2 mixed-subjects design, with the device being a between-subjects condition and news frames (episodic vs thematic) being a within-subjects condition. We find smaller knowledge gains from smartphone news exposure, which cannot be explained by differences in visual attention.
Additional file 1 of Length of stay and cost of care associated with admissions for atrial fibrillation among patients with cancer
Creators: name: Guha, Avirup
name: Jain, Anubhav
name: Aggarwal, Ankita
name: Dey, Amit K.
name: Dani, Sourbha
name: Ganatra, Sarju
name: Marchlinski, Francis E.
name: Addison, Daniel
name: Fradley, Michael G.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Supplementary methods, figures and tables.
title: Klinische Ergebnisse nach Hybridstabilisierung osteoporotisch-imponierender Frakturen der Brust- und Lendenwirbelsäule unter dem Aspekt des sagittalen Alignements nach einem mittleren Follow-up von 4 Jahren
Creators: name: Spiegl, Ulrich
name: Annemüller, Christine
name: Jarvers, Jan-Sven
name: Glasmacher, Stefan
name: Josten, Christoph
name: Heyde, Christoph E.
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: Osteoporotische Wirbelkörperfrakturen
subject: thorakolumbaler Übergang
subject: Hybridstabilisierung
subject: sagittale Balance
subject: 610 Medical sciences; Medicine

description: Fragestellung: Welche mittelfristigen Ergebnisse erwarten wir nach Hybridstabilisierung osteoporotischer Frakturen am thorakolumbalen Übergang insbesondere mit Analyse des sagittale Alignement? Methodik: Es handelt sich um eine retrospektive Kohortenstudie an einem Level I Traumazentrum.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2018)
title: Letale Trias beim polytraumatisierten Patienten – weiterhin relevant in der modernen Notfallmedizin?
Creators: name: Lang, Clara
name: Diepold, Eva
name: Hilber, Franz
name: Angerpointner, Katharina
name: Kerschbaum, Maximilian
name: Nerlich, Michael
name: Ernstberger, Antonio
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: Polytrauma
subject: Schwerstverletzte
subject: TraumaRegister
subject: Outcome
subject: Lethal Trias
subject: Multiple Trauma
subject: Letale Trias
subject: 610 Medical sciences; Medicine

description: Fragestellung: Die letale Trias (Koagulopathie, Hypothermie, Azidose) hat ein hohes Letalitätsrisiko - so die gängige Lehrmeinung. Wie stellt sich dieser Umstand im Jahr 2018 dar? Konnte im Zuge der allgemeinen Verbesserung der Schwerstverletztenversorgung auch die letale Trias bekämpft[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2018)
Kihnichthys Mcmahan, Matamoros, Piller & Chakrabarty, 2015, gen. nov.
Creators: name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
name: Piller, Kyle R.
name: Chakrabarty, Prosanta
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Cichlidae
Kihnichthys

description: Genus Kihnichthys gen. nov., McMahan and Matamoros 2015
(Fig. 9 and 10)
Inclusive species. K. ufermanni (type by monotypy)
Diagnosis. Kihnichthys is diagnosed by the presence of a dark caudal blotch filling the center, posterior portion of the caudal peduncle, as well as the presence of spatulate or chisel-like teeth in the anterior portions of the upper and lower jaws. Species of this genus possess a deep skull and large head with a small mouth. The lower jaw extends slightly beyond the upper jaw. The combination of these characters differentiates this genus from all other herichthyin genera. Vieja possesses a similar but larger caudal blotch, but also has conical or bicuspid (versus spatulate) teeth. Cincelichthys gen. nov. possesses spatulate teeth but has a small spot on the caudal peduncle (versus a larger spot in Kihnichthys).
Etymology. Gender masculine. The genus is named in honor of Herman A. Kihn, who has spent a lifetime studying the fishes of Guatemala. His work has made invaluable contributions to our understanding of the diversity and distributions of fishes in Guatemala.
Comments. Allgayer (2002) placed this enigmatic cichlid in Vieja in its original description. Few specimens exist in museum collections for this species, and most material comes from the Río La Pasion system, a tributary to the Río Usumacinta in Peten, Guatemala. Little is known about this cichlid and more comparative material and natural history information are certainly needed.
Material examined. MNHN 2002-1090 [n=1 (Holotype), Guatemala: Río Pucté], MNHN 2002-1091 [n=1 (Paratype), Guatemala: Río Pucté], MNHN 2002-1092 [n=1 (Paratype), Guatemala: Río Pucté].
description: Published as part of Mcmahan, Caleb D., Matamoros, Wilfredo A., Piller, Kyle R. & Chakrabarty, Prosanta, 2015, Taxonomy and systematics of the herichthyins (Cichlidae: Tribe Heroini), with the description of eight new Middle American Genera, pp. 211-234 in Zootaxa 3999 (2) on page 222, DOI: 10.11646/zootaxa.3999.2.3, http://zenodo.org/record/237045
„Feuerböcke“ der jüngeren Vorrömischen Eisenzeit im Milieu der Zarubincy-Kultur
Creators: name: Iarmulschi, Vasile
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Zarubincy-Kultur
subject: jüngere Vorrömische Eisenzeit
subject: Siedlungen
subject: Feuerböcke
subject: Migration
subject: Zarubincy culture
subject: Late Pre-Roman Iron Age
subject: settlements
subject: 900 Geschichte und Geografie::930 Geschichte des Altertums (bis ca. 499), Archäologie::930 Geschichte des Altertums bis ca. 499, Archäologie

description: Zu den Objekten aus Ton, die in den Siedlungen der Zarubincy-Kultur von Belii Grud und Litvinovič 3 gefunden wurden, gehören sog. Feuerböcke. Bislang sind lediglich zwei solcher Exemplare bekannt. Die Analogien zu diesen Exemplaren sind im Milieu der Poienești-Lucașeuca-Kultur – Borosești, Lunca Ciurei – sowie in Siedlungen des nördlichen Mitteleuropa, die in die Vorrömische Eisenzeit datiert werden – Bastrup, Hamburg-Volksdorf, Nowa Wieś, Ribe Amt usw. – zu verorten. Da die im nördlichen Mitteleuropa gefundenen Stücke älter sind, liegt der Ursprung der Feuerböcke wahrscheinlich im Norden.
description: Among the objects made of clay found in the settlements of the Zarubincy culture some pieces are probably parts of hearth grids. So far, only two such specimens have been found in the settlements at Belîi Grud and Litvinovič 3. The analogies to these specimens lay in the environment of the Poienești-Lucașeuca culture – Borosești, Lunca Ciurei – as well as in the settlements dated in the Late Pre-Roman Iron Age in Central-Northern Europe – Bastrup, Hamburg Volksdorf, Nowa Wieś, Ribe Amt etc. As the objects found in northern Central Europe are older, Nordic origin of such hearth grids remains highly probable.
[Prospect von der Burg Uster]
Creators: name: Kuhn, Jakob
Publisher: name: [s.n.]
Year: 1770
Subjects: Uster

description: [Jakob Kuhn]
description: Zuschreibung gemäss Vermerk auf dem Passepartout
description: Titel von fremder Hand auf dem Unterlagenblatt
description: Handschriftliche Bezeichnung "Uster" auf dem Unterlagenblatt; Nummer "17" unten links
Cincelichthys Mcmahan, Matamoros, Piller & Chakrabarty, 2015, gen. nov.
Creators: name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
name: Piller, Kyle R.
name: Chakrabarty, Prosanta
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Perciformes
Cichlidae
Cincelichthys

description: Genus Cincelichthys gen. nov., McMahan and Piller 2015
(Fig. 11)
Inclusive species. C. bocourti (type species by designation), C. pearsei
Diagnosis. Cincelichthys possess spatulate, chisel-like teeth, and species are deep-bodied and round or oval in overall body shape. Lateral markings appear along the body as wide, irregular bands dorsally to ventrally. Species possess solid black scales dispersed throughout the lateral sides of the body. White- or faint-colored spots are present on the medial and distal portions of the dorsal, caudal, and anal fins. Species possess a small mouth, with the lower jaw extending slightly beyond the upper jaw. The mouth is slightly upturned. A small black spot is present at the center and base of the caudal peduncle. The chisel-like teeth distinguish this genus from all others within the herichthyins except Kihnichthys, which also possesses chisel-like teeth, but exhibits a larger blotch filling the caudal peduncle, versus the small spot characteristic of Cincelichthys.
Distribution. Atlantic slope of Mexico, Belize, and Guatemala from the Río Grijalva-Usumacinta drainage to Lago Izabal (Río Dulce drainage basin).
Etymology. Gender masculine. “Cincel-“ is the Spanish word for chisel, in reference to the spatulate or chisellike teeth defining the genus. “-ichthys” is Greek for fish.
Comments. Previous molecular phylogenetic studies have recovered and recognized these two species as members of Theraps (McMahan et al. 2010; López-Fernández et al. 2010). The phylogeny presented here corroborates that of Říčan et al. (2013). Sufficient morphological differences (dentition, markings, orientation of the lower jaw) exist to diagnose a new genus for these two species. Cincelichthys bocourti was initially described as a member Neetroplus; however, this genus is a synonym of Hypsophrys, as the type species for Neetroplus is H. nematopus (Chakrabarty and Sparks 2007). Therefore, Neetroplus cannot be used for these species.
Material examined. C. bocourti; MNHN 1894-0241 [n=1 (Holotype), Guatemala: Lago Izabal], LSUMZ 16455 [n=11, Guatemala: Lago Izabal], FMNH 100620 [n=1, Belize: Belize District]; C. pearsei; FMNH 109053 [n=1, Guatemala: Río San Pedro], FMNH 109054 [n=3, Guatemala: Río San Pedro], FMNH 109055 [n=1, Guatemala: Río Usumacinta], UMMZ 144088 [n=10, Guatemala: Río San Pedro], LSUMZ 16227 [n=4, Guatemala: Río La Pasion], UMMZ 144088 [n=10, Guatemala: Río San Pedro].
description: Published as part of Mcmahan, Caleb D., Matamoros, Wilfredo A., Piller, Kyle R. & Chakrabarty, Prosanta, 2015, Taxonomy and systematics of the herichthyins (Cichlidae: Tribe Heroini), with the description of eight new Middle American Genera, pp. 211-234 in Zootaxa 3999 (2) on pages 223-224, DOI: 10.11646/zootaxa.3999.2.3, http://zenodo.org/record/237045
title: Multimodale neoadjuvante Therapie bei Weichteilsarkomen
Creators: name: Traub, Frank
name: Kopp, Hans-Georg
name: Paulsen, Frank
name: Sipos, Bence
name: Zips, Daniel
name: Eckert, Franziska
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: Weichteilsarkome
subject: Extremitäten
subject: Prognose
subject: Tumorortopädie
subject: Ansprechen
subject: 610 Medical sciences; Medicine

description: Fragestellung: Weichteilsarkome werden bei subfaszialem Sitz, mäßiger oder geringer Differenzierung und höherem Tumorstadium multimodal therapiert. Am Standort Tübingen werden diese Sarkome standardisiert mit einer präoperativen Strahlentherapie und einer zusätzlichen [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2018)