cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 8 of Heparin-enriched plasma proteome is significantly altered in Alzheimer’s disease
Creators: name: Guo, Qi
name: Ping, Lingyan
name: Dammer, Eric B.
name: Duong, Duc M.
name: Yin, Luming
name: Xu, Kaiming
name: Shantaraman, Anantharaman
name: Fox, Edward J.
name: Golde, Todd E
name: Johnson, Erik C.B.
name: Roberts, Blaine R.
name: Lah, James J.
name: Levey, Allan I.
name: Seyfried, Nicholas T.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 8: Supplemental Figure 8. Overlap between additional human brain network modules and differentially abundant Hp-enriched plasma proteins in AD. Protein expression trends are examined for the 10 modules that exhibit significant overlap with differentially abundant Hp-enriched plasma proteome but demonstrate moderate to low correlation with AD clinicopathological traits in the brain. Brain module abundance is quantified by eigenprotein values derived from the consensus brain dataset (11) (control = 101, AsymAD = 181, AD = 174), while volcano plots illustrate the differential abundance (log2 AD vs CTL) of module proteins overlapped with the Hp-enriched plasma proteome. The statistical significance of changes in module eigenprotein abundance across the three groups in the consensus brain cohort was assessed using ANOVA with Tukey post-hoc correction. Modules with p < 0.05 were considered significant. Among these modules, M4 ‘Synaptic transmission’, M34 ‘GTP binding’, M14 ‘Protein folding’, M37 ‘Endosome’, M30‘Proteasome’, M43 ‘Ribonucleoprotein binding’ and M38 ‘Heat shock/protein folding’ consist of proteins with decreased abundance in AD plasma, while M40‘Antigen binding’ exclusively contains increased plasma proteins in AD. M27‘ECM’ and M21 ‘MHC/immune’ exhibit a balanced representation of both increased and decreased plasma proteins in AD. CTL, control; AsymAD, asymptomatic AD.
A Topological SQUIPT based on helical edge states in proximity to superconductors
Creators: name: Bours, Lennart
name: Sothmann, Björn
name: Carrega, Matteo
name: Strambini, Elia
name: Hankiewicz, Ewelina M.
name: Molenkamp, Laurens W.
name: Giazotto, Francesco
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We propose a device based on a topological Josephson junction where the helical edge states of a two-dimensional topological insulator are in close proximity to two superconducting leads. The presence of a magnetic flux through the junction leads to a Doppler shift in the spectrum of Andreev bound states, and affects the quantum interference between proximized edge states. We inspect the emergent features, accessing the density of states through a tunnel-coupled metallic probe, thus realizing a Topological Superconducting Quantum Interference Proximity Transistor (TSQUIPT). We calculate the expected performances of this new device, concluding that it can be used as a sensitive, absolute magnetometer due to the voltage drop across the junction decaying to a constant value as a function of the magnetic flux. Contrary to conventional SQUID and SQUIPT designs, no ring structure is needed. The findings pave the way for novel and sensitive devices based on hybrid devices that exploit helical edge states.
description: 8 pages, 7 figures
Reservoir Computing and Photoelectrochemical Sensors: A Marriage of Convenience
Creators: name: Abdi, Gisya
name: Alluhaibi, Lulu
name: Kowalewska, Ewelina
name: Mazur, Tomasz
name: Mech, Krzysztof
name: Podborska, Agnieszka
name: Sławek, Andrzej
name: Tanaka, Hirofumi
name: Szaciłowski, Konrad
Publisher: name: arXiv
Year: 2025
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Emerging Technologies (cs.ET)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Sensing technology is an important aspect of information processing. Current development in artificial intelligence systems (especially those aimed at medical and environmental applications) requires a lot of data on the chemical composition of biological fluids or environmental samples. These complex matrices require advanced sensing devices, and photoelectrochemical ones seem to have potential to overcome at least some of the obstacles. Furthermore, the development of artificial intelligence (AI) technology for autonomous robotics requires technology mimicking human senses, also those operating at the molecular level, such as gustation and olfaction. Again, photoelectrochemical sensing can provide some suitable solutions. In this review, we introduce the idea of integration of photoelectrochemical sensors with some unconventional computing paradigm - reservoir computing. This approach should not only boost the performance of the sensors itself, but also open new pathways through science. Integration of sensing devices with computing systems will also contribute to a better understanding (or at least mimicking) of the human senses and neuromorphic sensory information processing. Although reservoir systems can be considered magic "black boxes" and their operation is at the same time simple and hard to comprehend, this combination is expected to open a new era of effective information harvesting and processing systems.
[Proceedings of the Supreme Court of British Columbia 1989-05-18]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.
CONALD Report on the Workshop on Learning from Text and the Web
Creators: name: Carbonell, Jaime G.
name: Craven, Mark
name: Fienberg, Steve
name: Mitchell, Tom
name: Yiming  Yang
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: An increasing fraction of the world's information and data is now represented in textual form. For example, the World Wide Web, online news feeds, and other Internet sources contain a tremendous volume of information. However, users seeking information do not have unlimited attention, and therefore methods of summarizing, clustering, categorizing and discovering patterns in the information space are required.
“The Elite vs. The People’s Party of Canada: Maxime Bernier and the Manifestation of Populism in Canada”
Creators: name: Beer-Beauchamp, Emma
Publisher: name: My University
Year: 2020

description: The purpose of this Major Research Paper (MRP) is to determine if measuring populism is possible simply by reading political leaders’ tweets. In this MRP, the manifestation of populism in Canada is measured by analyzing the tweets of the People’s Party of Canada leader Maxime Bernier, Conservative Party leader Andrew Scheer, New Democratic Party leader Jagmeet Singh and Liberal Party leader Justin Trudeau. This MRP seeks to determine whether Maxime Bernier or any other federal party leader is a populist by analyzing their tweets during the 2019 federal election campaign through a detailed coding scheme. Before analyzing the tweets using a mix of quantitative and qualitative research analyses, I provide a literature review and a clear definition of the term populism. I also present a short history of populism in Canada and determine where the applicable party leaders fit into this history today. A main challenge with identifying populism is that it is widespread on the right and on the left. I observed that both Bernier and Singh are populists. This result aligned with the literature on populism that confirms populism can be found anywhere along the political spectrum. Keywords: Populism, Canadian Politics, Electoral Politics, Elections, Twitter, Political Parties
Expectations for dihadron correlation measurements at the LHC
Creators: name: Renk, Thorsten
name: Eskola, Kari J.
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The suppression of high transverse momentum (P_T) inclusive hadron spectra in heavy-ion collisions as compared to the scaled expectation of high P_T hadron production in p-p collisions is the most direct manifestation of the interaction of hard partons with the soft bulk medium produced in heavy-ion collisions which is absent in p-p collisions. Yet the measured nuclear suppression factor R_AA is a very averaged quantity and hence only a limited amount of information about the medium evolution and the nature of the interaction with the medium can be deduced from R_AA. Measurements of hard back-to-back hadron correlations in 200 AGeV Au-Au collisions at RHIC have opened a new window to study the energy loss of partons in a medium in a more differential way and for a different distribution of in-medium pathlengths than in the case of R_AA. In this work, we present an extrapolation of our results for back-to-back yields at RHIC energies to 5.5 TeV Pb-Pb collisions at the CERN LHC. We also discuss differences and similarities between the measurement at RHIC.
description: 9 pages, 7 figures
Additional file 1 of Risk factors associated with short-term adverse events after SARS-CoV-2 vaccination in patients with immune-mediated inflammatory diseases
Creators: name: Wieske, Luuk
name: Kummer, Laura Y. L.
name: van Dam, Koos P. J.
name: Stalman, Eileen W.
name: van der Kooi, Anneke J.
name: Raaphorst, Joost
name: Löwenberg, Mark
name: Takkenberg, R. Bart
name: Volkers, Adriaan G.
name: D’Haens, Geert R. A. M.
name: Tas, Sander W.
name: Spuls, Phyllis I.
name: Bekkenk, Marcel W.
name: Musters, Annelie H.
name: Post, Nicoline F.
name: Bosma, Angela L.
name: Hilhorst, Marc L.
name: Vegting, Yosta
name: Bemelman, Frederike J.
name: Killestein, Joep
name: van Kempen, Zoé L. E.
name: Voskuyl, Alexandre E.
name: Broens, Bo
name: Sanchez, Agner Parra
name: Wolbink, Gertjan
name: Boekel, Laura
name: Rutgers, Abraham
name: de Leeuw, Karina
name: Horváth, Barbara
name: Verschuuren, Jan J. G. M.
name: Ruiter, Annabel M.
name: van Ouwerkerk, Lotte
name: van der Woude, Diane
name: Allaart, Cornelia F.
name: Teng, Y. K. Onno
name: van Paassen, Pieter
name: Busch, Matthias H.
name: Jallah, B. Papay
name: Brusse, Esther
name: van Doorn, Pieter A.
name: Baars, Adája E.
name: Hijnen, Dirkjan
name: Schreurs, Corine R. G.
name: van der Pol, W. Ludo
name: Goedee, H. Stephan
name: Steenhuis, Maurice
name: Rispens, Theo
name: ten Brinke, Anja
name: Verstegen, Niels J. M.
name: Zwinderman, Koos A. H.
name: van Ham, S. Marieke
name: Kuijpers, Taco W.
name: Eftimov, Filip
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1. Adverse events questionnaire.
[Proceedings of the Supreme Court of British Columbia 1989-05-19]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.
Ecopolitics Podcast, Episode 11: Environmental Political Economy
Creators: name: Katz-Rosene, Ryan
name: Andrée, Peter
Publisher: name: My University
Year: 2020

description: What is the relationship between capitalism and the environment? In this episode Dr. Laurie Adkin, Professor of Political Science at the University of Alberta, provides some answers by guiding us on a journey through the world of 'environmental political economy'. [Produced by Nicole Bedford; Artwork by Adam Gibbard; Transcription by Allison Brown; Additional Resources prepared by Ashley Fearnall].
Computing the volume element of a family of metrics on the multinomial simplex
Creators: name: Lebanon, Guy
Publisher: name: Carnegie Mellon University
Year: 1995
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Abstract: "We compute the differential volume element of a family of metrics on the multinomial simplex. The metric family is composed of pull-backs of the Fisher information metric through a continuous group of transformations. This note complements the paper by Lebanon [3] that describes a metric learning framework and applies the results below to text classification."
Probiotics: A Possible Preventative Measure of Atopic Asthma?
Creators: name: Ogundu, Homa
name: Hachemi, Lina
name: Namulla, Niharika
Publisher: name: My University
Year: 2017

description: Introduction: Asthma is a chronic inflammatory immune disorder characterized by acute episodes of bronchial hyper responsiveness. This is caused by recurrent dysregulation of several immunoregulatory proteins such as interleukins, cytokines, clusters of differentiation, and immunoglobulins . In Canada and the U.S, the risks of developing atopic asthma can range from 1 case in every 10 children (general population), to 1 case in every 5 children (high-risk populations: African American descent). Asthma has an incidence rate of 8.5 million cases each year while the prevalence is 161.3 cases /1000 person years, depending on the population and environment studied. Children with decreased microbial exposure were observed to develop an altered gut microbiota leading to a higher risk for the development of asthma and allergic diseases. Objective: The aim of this review is to examine if probiotics decrease the risk of developing atopic asthma in children with an abnormal gut microbiome. Methodology: Concepts pertaining to the research question were identified and expanded upon through keywords: risk, and asthma or immune function, and probiotics or gut microbiome. Peer reviewed journals published between the years 2007-2017, from Canada and/or U.S.A were examined. Exclusion criteria included terms relating to airway, throat and respiratory microbiota to eliminate articles irrelevant to the focus of this study. The search strategy was developed on PubMed and adapted to Scopus, Journal of Allergy and Clinical Immunology and Journal of Pediatric Allergy and Immunology to yield the most relevant research articles. This resulted in 61 articles, from which 8 relevant articles were deemed eligible for the making of this literature review. Results: The 8 most relevant studies consisted of 2 systematic reviews and meta-analyses (one being meta-analysis only), 2 prospective nested case-control studies, and only 1 cohort and RCT each. The RCT study showed a positive correlation between the administration of probiotics and the reduction of asthma onset, while all three case-controls and cohorts listed an altered gut microbiota as a causative risk factor for developing asthma. Lastly, the 2 systematic reviews and meta-analyses concluded that no clinically-relevant association was present between the administration of probiotics and the prevention of asthma development. Conclusion: Due to the large heterogeneity of results, little compiled evidence supports a relation between the delivery of probiotics and the prevention of asthma development as of yet. Studies more specific to probiotics in relation to asthma development in larger cohorts need to be conducted to better understand any possible associations.
Redefining a University Library’s Reference Service in 2018: A Continuum of Service
Creators: name: Fournier, Karine
Publisher: name: My University
Year: 2019
Subjects: reference service
Academic Library
Health Sciences Library
One-service desk
individualized research consultations

description: The University of Ottawa Health Sciences Library (HSL) has completely redefined its services to users over the past three years to better reflect the changing needs of library users, such as preference for digital over print, and increasing needs for teaching and research support. This presentation will provide an overview of HSL initiatives through: 1) The merger of the circulation and reference services This fusion of services meant a redistribution of employees’ tasks, where librarians withdrew from the reference desk and where support staff increased their knowledge of the reference service through several training sessions. This uptraining enabled employees to offer a basic reference services to users and allowed them to better allocate (triage) appropriate user requests. 2) The development of an individualized research consultation service Individualized consultations are tailored appointments for health sciences and medicine students and researchers offered by librarians, in order to provide in-depth assistance for their research projects, large or small. 3) The development of a triage service for consultations This triage service was intended to meet different needs: help a colleague with a temporary request overload, or to take care of requests directly from the service point referred by support staffs. The objective of these different services is to help our users based on a continuum of service, that is, from simple to complex requests, and this, in a completely fluid and transparent manner for library users. Learning objectives: -Participants will gain applied knowledge on how to change their service model, with tips on how to best overcome obstacles. -Participants will learn how to best use certain tools, such as LibCal, to create a seamless service to their users.
KNOWM Memristors in a Bridge Synapse delay-based Reservoir Computing system for detection of epileptic seizures
Creators: name: Przyczyna, Dawid
name: Hess, Grzegorz
name: Szaciłowski, Konrad
Publisher: name: arXiv
Year: 2025
Subjects: subject: Medical Physics (physics.med-ph)
subject: Emerging Technologies (cs.ET)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Nanodevices that show the potential for non-linear transformation of electrical signals and various forms of memory can be successfully used in new computational paradigms, such as neuromorphic or reservoir computing (RC). Dedicated hardware implementations based on functional neuromorphic structures significantly reduce energy consumption and/or increase computational capabilities of a given artificial neural network system. Concepts of RC, which as a flexible computational paradigm can be highly inclusive, are often used as a model to describe computations performed in materia. With mostly fixed internal structure, solid-state devices, especially memristors, are studied as computational substrates in various RC systems. In this work, we present single-node Echo State Machine (SNESM) RC system based on bridge synapse as a computational substrate (consisting of 4 memristors and a differential amplifier) used for epileptic seizure detection. KNOWM memristors were posed as ideal candidates because of their easy prototyping and reliability of operation. In this account, we present an application of commercially available KNOWM memristors in various neuromorphic applications, from simple analysis of switching and internal dynamics (elucidated form noise spectroscopy and total harmonic distortion analysis) to the classification and recognition of complex time series: epilepsy seizure recognition using a wrist-worn triaxial accelerometer.
[Proceedings of the Supreme Court of British Columbia 1989-05-23]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.
Computing the Optimal Strategy to Commit to
Creators: name: Conitzer, Vincent
name: Sandholm, Tuomas W
Publisher: name: Carnegie Mellon University
Year: 2003
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: In multiagent systems, strategic settings are often analyzed under the assumption that the players choose their strategies simultaneously. However, this model is not always realistic. In many settings, one player is able to commit to a strategy before the other player makes a decision. Such models
are synonymously referred to as leadership, commitment, or Stackelberg models, and optimal play in such models is often signicantly different from optimal play in the model where strategies are selected simultaneously. The recent surge in interest in computing game-theoretic solutions has so far ignored leadership models (with the exception of the interest in mechanism design, where the designer is implicitly in a leadership position). In this paper, we study how to compute optimal strategies to commit to under both commitment to pure strategies and commitment to mixed strategies, in both normal-form and Bayesian games. We give both positive results (e±cient algorithms) and negative results (NP-hardness results).
Additional file 7 of Heparin-enriched plasma proteome is significantly altered in Alzheimer’s disease
Creators: name: Guo, Qi
name: Ping, Lingyan
name: Dammer, Eric B.
name: Duong, Duc M.
name: Yin, Luming
name: Xu, Kaiming
name: Shantaraman, Anantharaman
name: Fox, Edward J.
name: Golde, Todd E
name: Johnson, Erik C.B.
name: Roberts, Blaine R.
name: Lah, James J.
name: Levey, Allan I.
name: Seyfried, Nicholas T.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 7: Supplemental Figure 7. Comparing TMT-MS proteomic measurements of human brain generated by FragPipe (FP) and Proteome Discoverer (PD). A) 456 raw files collected from the ROSMAP and Banner cohorts as previously described (11) underwent a database search using FP (see methods), resulting in the identification of 8956 UniprotID-identified proteins, each with measurements available in 50% or more across 456 individual cases (control = 101, AsymAD = 181, AD = 174). These proteins were subsequently assigned to one of the 44 pre-existing consensus network modules (11) by re-calculating the kME (bicor correlation to module eigenprotein) for each protein and assigning it to the module that exhibited the highest correlation (52). B) The number and overlap of unique gene products identified in the FP and the PD outputs, with 7476 overlapping between the two datasets. FP provided an additional 1428 unique gene products compared to PD, resulting in an 18% increase in proteome coverage. C) Scatter plots illustrate the correlation between log2 fold-change for AD vs CTL (left, cor= 0.9, p < 1e-200) and AsymAD vs CTL (right, cor = 0.84, p < 1e-200), using common gene products (N = 7467) found in both FP and PD search results. CTL, control; cor, Pearson correlation of coefficient.
Additional file 2 of Risk factors associated with short-term adverse events after SARS-CoV-2 vaccination in patients with immune-mediated inflammatory diseases
Creators: name: Wieske, Luuk
name: Kummer, Laura Y. L.
name: van Dam, Koos P. J.
name: Stalman, Eileen W.
name: van der Kooi, Anneke J.
name: Raaphorst, Joost
name: Löwenberg, Mark
name: Takkenberg, R. Bart
name: Volkers, Adriaan G.
name: D’Haens, Geert R. A. M.
name: Tas, Sander W.
name: Spuls, Phyllis I.
name: Bekkenk, Marcel W.
name: Musters, Annelie H.
name: Post, Nicoline F.
name: Bosma, Angela L.
name: Hilhorst, Marc L.
name: Vegting, Yosta
name: Bemelman, Frederike J.
name: Killestein, Joep
name: van Kempen, Zoé L. E.
name: Voskuyl, Alexandre E.
name: Broens, Bo
name: Sanchez, Agner Parra
name: Wolbink, Gertjan
name: Boekel, Laura
name: Rutgers, Abraham
name: de Leeuw, Karina
name: Horváth, Barbara
name: Verschuuren, Jan J. G. M.
name: Ruiter, Annabel M.
name: van Ouwerkerk, Lotte
name: van der Woude, Diane
name: Allaart, Cornelia F.
name: Teng, Y. K. Onno
name: van Paassen, Pieter
name: Busch, Matthias H.
name: Jallah, B. Papay
name: Brusse, Esther
name: van Doorn, Pieter A.
name: Baars, Adája E.
name: Hijnen, Dirkjan
name: Schreurs, Corine R. G.
name: van der Pol, W. Ludo
name: Goedee, H. Stephan
name: Steenhuis, Maurice
name: Rispens, Theo
name: ten Brinke, Anja
name: Verstegen, Niels J. M.
name: Zwinderman, Koos A. H.
name: van Ham, S. Marieke
name: Kuijpers, Taco W.
name: Eftimov, Filip
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 2: Table S1. Demographics. Figure S1. Study flowchart. Figure S2. Adverse events in patients with IMIDs after SARS-CoV-2 vaccination. Figure S3. Adverse events after SARS-CoV-2 vaccination per IMID.
A Novel Contact Resistance Model of Anisotropic Conductive Film for FPD Packaging
Creators: name: Wang, Gou-Jen
name: Lin, Yi-Chin
name: Lin, Gwo-Sen
Publisher: name: arXiv
Year: 2007
Subjects: subject: Other Computer Science (cs.OH)
subject: FOS: Computer and information sciences

description: In this research, a novel contact resistance model for the flat panel display (FPD) packaging based on the within layer parallel and between layers series resistance concepts was proposed. The FJ2530 anisotropic conductive films (ACF) by Sony Inc. containing the currently smallest 3micron conductive particles was used to conduct the experiments to verify the accuracy of the proposed model. Calculated resistance of the chip-on-glass (COG) packaging by the proposed model is 0.163Ω. It is found that the gold bump with 0.162Ωresistance play the major role of the overall resistance. Although the predicted resistance by the proposed model is only one third of the experimentally measured value, it has been three-fold improvement compared to the existing models.
description: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions)
The Immunomodulatory and Anti-Inflammatory Role of Polyphenols
Creators: name: Yahfoufi, Nour
name: Alsadi, Nawal
name: Jambi, Majed
name: Matar, Chantal
Publisher: name: My University
Year: 2018
Subjects: T helper 1 (Th1)
Th17
Treg
anti-inflammation
anti-tumorigenic
arachidonic acid
cancer
chronic inflammatory conditions
cyclooxygenase (COX)
cytokines
extra-cellular signal regulated kinases (ERK)
immune system
inflammation
inhibitor of kappa kinase (IKK)
lipoxygenase (LOX)
macrophages
mitogen-activated protein Kinase (MAPK)
molecular mechanisms
nitric oxide synthase (NOS)
nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)
oxidative stress
polyphenols
reactive oxygen species (ROS)
superoxide dismutase (SOD)
Animals
Anti-Inflammatory Agents
Cytokines
Gene Expression Regulation
Humans
Immunologic Factors
Polyphenols

description: This review offers a systematic understanding about how polyphenols target multiple inflammatory components and lead to anti-inflammatory mechanisms. It provides a clear understanding of the molecular mechanisms of action of phenolic compounds. Polyphenols regulate immunity by interfering with immune cell regulation, proinflammatory cytokines' synthesis, and gene expression. They inactivate NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) and modulate mitogen-activated protein Kinase (MAPk) and arachidonic acids pathways. Polyphenolic compounds inhibit phosphatidylinositide 3-kinases/protein kinase B (PI3K/AkT), inhibitor of kappa kinase/c-Jun amino-terminal kinases (IKK/JNK), mammalian target of rapamycin complex 1 (mTORC1) which is a protein complex that controls protein synthesis, and JAK/STAT. They can suppress toll-like receptor (TLR) and pro-inflammatory genes' expression. Their antioxidant activity and ability to inhibit enzymes involved in the production of eicosanoids contribute as well to their anti-inflammation properties. They inhibit certain enzymes involved in reactive oxygen species ROS production like xanthine oxidase and NADPH oxidase (NOX) while they upregulate other endogenous antioxidant enzymes like superoxide dismutase (SOD), catalase, and glutathione (GSH) peroxidase (Px). Furthermore, they inhibit phospholipase A2 (PLA2), cyclooxygenase (COX) and lipoxygenase (LOX) leading to a reduction in the production of prostaglandins (PGs) and leukotrienes (LTs) and inflammation antagonism. The effects of these biologically active compounds on the immune system are associated with extended health benefits for different chronic inflammatory diseases. Studies of plant extracts and compounds show that polyphenols can play a beneficial role in the prevention and the progress of chronic diseases related to inflammation such as diabetes, obesity, neurodegeneration, cancers, and cardiovascular diseases, among other conditions.
Measurement Technique for Elastic and Mechanical Properties of Polycrystalline Silicon-Germanium Films Using Surface Acoustic Waves and Projection Masks
Creators: name: Bennis, A.
name: Leinenbach, C.
name: Raudzis, C.
name: Müller-Fiedler, R.
name: Kronmüller, S.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Other Computer Science (cs.OH)
subject: FOS: Computer and information sciences

description: Using Rayleigh surface acoustic waves (SAW), the Young's modulus, the density and the thickness of polycrystalline Silicon-Germanium (SiGe) films deposited on silicon and SiO2 were measured, in excellent agreement with theory. The dispersion curve of the propagating SAW is calculated with a Boundary Element Method (BEM)-Model based on Green's functions. The propagating SAW is generated with a nanosecond laser in a narrowband scheme projecting stripes from a mask on the surface of the sample. For this purpose a glass mask and a liquid crystal display (LCD) mask are used. The slope of the SAW is then measured using a probe beam setup. From the wavelength of the mask and the frequency of the measured SAW, the dispersion curve is determined point by point. Fitting the BEM-Model to the measured nonlinear dispersion curve provides several physical parameters simultaneously. In the present work this is demonstrated for the Young's modulus, the density and the thickness of SiGe films. The results from the narrowband scheme measurement are in excellent agreement with separated measurements of the thickness (profilometer), the density (balance) and the Young's modulus (nanoindenter).
description: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions)
[Proceedings of the Supreme Court of British Columbia 1989-05-24]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.
title: 01_0021
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Lignans from Schisandra chinensis rattan stems suppresses primary Aβ1-42-induced microglia activation via NF-κB/MAPK signaling pathway
Creators: name: Yang, Bingyou
name: Han, Wei
name: Han, Hua
name: Liu, Yan
name: Guan, Wei
name: Kuang, Haixue
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Microglia cells play important roles in neurodegenerative diseases for clearing amyloid-β and reducing the occurrence of inflammation. In this study, the neuroinflammatory effect and the mechanism of lignans from Schisandra chinensis rattan stems (rsSCH-L) were evaluated by Aβ1-42-induced primary microglia cell model. The results have shown that rsSCH-L could reduce the levels of pro-inflammatory cytokines, including IL-1β, TNF-α and NO. Moreover, rsSCH-L suppressed the phosphorylations of NF-κB and IκBα as well as p38, JNK and ERK proteins in Aβ1-42-induced microglia cells. Taken together, rsSCH-L could attenuate microglia cells from neuroinflammation by activating the NF-κB/MAPK signaling pathway.
[Proceedings of the Supreme Court of British Columbia 1989-05-25]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.
Les familles en trans-formation : Les réalités vécues des parents trans et de leur famille en Ontario et au Québec
Creators: name: Delorme, Isabel Maria
Publisher: name: My University
Year: 2023

description: Malgré nos développements sociopolitiques, les modèles de pensée et de pratiques propres à la culture canadienne sur le genre et la famille, particulièrement fondés sur des valeurs occidentales, restent largement incontestés. Les notions de « mère » et de « père » se trouvent si profondément ancrées dans notre imaginaire culturel qu’un concept de parentalité détaché des notions du genre comme immuable n’est pas facilement concevable. C’est en raison du manque de reconnaissance des parents trans et non conformes de genre dans les conceptions familiales que ce mémoire cherche à documenter de manière cohérente et critique les réalités des parents trans et de leur famille, et surtout de définir les points d’intérêt en fonction desquels de futures stratégies et paradigmes plus critiques pourront être lancés. Cette question est abordée par le biais d’une analyse thématique de la littérature existante sur les principales expériences des parents trans, et ce, à partir d’un cadre théorique transféministe. Cette recension des écrits révèle que très peu d’attention scientifique hors des études trans a été portée sur les enjeux de transparentalité, en partie à cause des discours cisgenristes rendant la transitude symboliquement incompatibles avec nos notions dominantes de la famille et de la parentalité. Malgré cela, de plus en plus de personnes trans et non conformes de genre deviennent parents et vivent en famille. Ces familles diverses se retrouvent souvent vulnérables, délégitimées et discriminées, rendant difficile l’accès à certains services et la navigation de certaines institutions. Toutefois, les parents et les familles trans présentent des forces et des qualités uniques qui nous invitent à imaginer de nouveaux modèles de famille et de filiation plus critiques et plus affirmatifs. Pour traiter de ces enjeux, ce mémoire est divisé en quatre chapitres. Le premier décrit les fondements théoriques et méthodologiques du projet. Le deuxième examine les réalités et parcours des parents et familles pré-transition (où la parentalité ait débuté avant un coming out ou une transition par la personne parent trans). Le troisième chapitre aborde les réalités et parcours des parents et familles post-transition (oû la parentalité ait débuté suite à ou durant un coming out ou une transition par la personne parent trans). Le quatrième et dernier chapitre discute des résultats de cette recherche et propose des recommandations pour favoriser des approches plus affirmatives sur la famille et sur les enjeux trans. Mots-clés : Travail social, trans, transgenre, non binaire, parentalité, transparentalité, familles LGBTQ+, adoption, procréation assistée, famille, filiation, études de la famille, transition, identité de genre, identité parentale, transféminisme, diversité sexuelle et de genre, diversité familiale.
Computing Quantitative Characteristics of Finite-State Real-Time Systems
Creators: name: S  Campos
name: Clarke, Edmund M
name: W.  Marrero
name: M  Minea
name: H  Hiraishi
Publisher: name: Carnegie Mellon University
Year: 1973
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Presents a general method for computing quantitative information about finite-state real-time systems. We have developed algorithms that compute exact bounds on the delay between two specified events and on the number of occurrences of an event in a given interval. This technique allows us to determine performance measures such as schedulability, response time, and system load. Our algorithms produce more detailed information than traditional methods. This information leads to a better understanding of system behavior, in addition to determining its correctness. The algorithms presented in this paper are efficiently implemented using binary decision diagrams and have been incorporated into the SMV symbolic model verifier. Using this method, we have verified a model of an aircraft control system with 1015 states. The results obtained demonstrate that our method can be successfully applied in the verification of real-time system designs
[Proceedings of the Supreme Court of British Columbia 1989-05-26]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.
[Proceedings of the Supreme Court of British Columbia 1989-06-05]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.
High Abundances of Presolar Grains and $^{15}$N-rich Organic Matter in CO3.0 Chondrite Dominion Range 08006
Creators: name: Nittler, Larry R.
name: Alexander, Conel M. O'D.
name: Davidson, Jemma
name: Riebe, My E. I.
name: Stroud, Rhonda M.
name: Wang, Jianhua
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: NanoSIMS C-, N-, and O-isotopic mapping of matrix in CO3.0 chondrite Dominion Range (DOM) 08006 revealed it to have in its matrix the highest abundance of presolar O-rich grains (257 +76 / -96 ppm, 2$σ$) of any meteorite. It also has a matrix abundance of presolar SiC of 35 (+25 / -17, 2$σ$) ppm, similar to that seen across primitive chondrite classes. This provides additional support to bulk isotopic and petrologic evidence that DOM 08006 is the most primitive known CO meteorite. Transmission electron microscopy of five presolar silicate grains revealed one to have a composite mineralogy similar to larger amoeboid olivine aggregates and consistent with equilibrium condensation, two non-stoichiometric amorphous grains and two olivine grains, though one is identified as such solely based on its composition. We also found insoluble organic matter (IOM) to be present primarily as sub-micron inclusions with ranges of C- and N-isotopic anomalies similar to those seen in primitive CR chondrites and interplanetary dust particles. In contrast to other primitive extraterrestrial materials, H isotopic imaging showed normal and homogeneous D/H. Most likely, DOM 08006 and other CO chondrites accreted a similar complement of primitive and isotopically anomalous organic matter to that found in other chondrite classes and IDPs, but the very limited amount of thermal metamorphism experienced by DOM 08006 has caused loss of D-rich organic moieties, while not substantially affecting either the molecular carriers of C and N anomalies or most inorganic phases in the meteorite. One C-rich grain that was highly depleted in $^{13}$C and $^{15}$N was identified; we propose it originated in the Sun's parental molecular cloud.
description: accepted for publication in Geochimica Cosmochimica Acta; 28 pages of text, 17 figures, 4 tables
Additional file 1 of Role of baseline soluble tumor necrosis factor receptor 2 as a biomarker in primary podocytopathy: Implications for renal impairment and disease progression
Creators: name: Nagaram, Srinivas
name: Charles, Priscilla
name: Nisha, Yadav
name: Stephen, Norton
name: Hanumanthappa, Nandeesha
name: Parameswaran, Sreejith
name: Chinnakali, Palanivel
name: Nachiappa Ganesh, Rajesh
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Supplementary Material 1: Table 1. Correlation analysis for TNFR2 expression in renal biopsies with Histopathological chronicity scores
Additional file 1 of Comparison of calculated remnant lipoprotein cholesterol levels with levels directly measured by nuclear magnetic resonance
Creators: name: Chen, Jin
name: Kuang, Jie
name: Tang, Xiaoyu
name: Mao, Ling
name: Guo, Xin
name: Luo, Qin
name: Peng, Daoquan
name: Yu, Bilian
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Additional file 1: Table S1. Experimental Parameters. Table S2. Values of (RCe-RCn)/RCn at fasting, 2 h and 4 h postprandial states according to TGe-low group and TGe-high group. Table S3. Logistic regression analysis for the association of RCe and RCn with CAD in fasting and non-fasting states (n = 98)
Additional file 1 of Ruminant microbiome data are skewed and unFAIR, undermining their usefulness for sustainable production improvement
Creators: name: Ortiz-Chura, Abimael
name: Popova, Milka
name: Morgavi, Diego P.
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1
Computing Equilibria in Multiplayer Stochastic Games of Imperfect Information
Creators: name: Ganzfried, Sam
name: Sandholm, Tuomas W
Publisher: name: Carnegie Mellon University
Year: 2005
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Computing a Nash equilibrium in multiplayer stochastic games is a notoriously difﬁcult problem. Prior algorithms have been proven to converge in extremely limited settings and have only been tested on small problems. In contrast, we recently presented an algorithm for computing approximate jam/fold equilibrium strategies in a three-player nolimit Texas hold’em tournament—a very large realworld stochastic game of imperfect information [5]. In this paper we show that it is possible for that algorithm to converge to a non-equilibrium strategy proﬁle. However, we develop an ex post procedure
that determines exactly how much each player can gain by deviating from his strategy and conﬁrm thatnthe strategies computed in that paper actually do
constitute an equilibrium for a very small (0.5% of the tournament entry fee). Next, we develop several new algorithms for computing a Nash equilibrium in multiplayer stochastic games (with perfect or imperfect information) which can provably never converge to a non-equilibrium. Experiments show
that one of these algorithms outperforms the original algorithm on the same poker tournament. In short, we present the ﬁrst algorithms for provably
computing an equilibrium of a large stochastic game for small. Finally, we present an efﬁcient algorithm that minimizes external regret in both the perfect and imperfect information cases.
[Proceedings of the Supreme Court of British Columbia 1989-06-06]
Creators: name: British Columbia. Supreme Court
Publisher: name: Vancouver : United Reporting Service Ltd.
Year: 2013

description: In the Supreme Court of British Columbia, between: Delgamuukw, also known as Albert Tait, suing on his own behalf and on behalf of all the members of the House of Delgamuukw, and others, plaintiffs, and Her Majesty the Queen in right of the Province of British Columbia and the Attorney General of Canada, defendants: proceedings at trial.