cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Healthcare resource utilization and costs among patients with relapsed and/or refractory multiple myeloma treated with proteasome inhibitors in real-world clinical practice in Germany
Creators: name: H. Tilman Steinmetz
name: Moushmi Singh
name: Lebioda, Andrea
name: Fink, Leah
name: Schoehl, Martina
name: Rieth, Achim
name: Gonzalez-McQuire, Sebastian
name: Engelhardt, Monika
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: To assess the real-world healthcare resource utilization (HRU) and costs associated with different proteasome inhibitors (PIs) for the treatment of patients with relapsed and/or refractory multiple myeloma (RRMM) in Germany. We conducted a retrospective medical chart review of treatment patterns, outcomes, and HRU for patients with RRMM treated with bortezomib, carfilzomib, or ixazomib in second- or third-line (2L or 3L) therapy in Germany. Data were collected between 1 January 2017 and 30 June 2017. Costs were calculated based on drug prices and unit costs in Germany. Physicians provided data on 302 patients. Mean monthly total direct costs per patient receiving PI-based therapy were €7,925 and €10,693 for 2L and 3L, respectively, of which approximately 90% was anti-myeloma drug costs. Overall, the highest costs were associated with patients receiving 3L therapy. Regardless of treatment line, costs were higher for patients who had received a stem cell transplant (SCT) in a previous treatment line than for those who had not; the data suggest that this reflects the use of triplet regimens following a SCT. Patients with a complete response (CR) experienced no unplanned hospitalizations during the study period, whereas patients with progressive disease experienced the highest number of unplanned and planned hospitalizations. In 2L therapy, the highest proportion of patients with a CR was observed in those receiving carfilzomib (12% carfilzomib; 4% bortezomib; 0% ixazomib). Patients with missing or incomplete follow-up data were included in the study and were accounted for using monthly cost estimates. Anti-myeloma drugs were the main contributor to total HRU costs associated with RRMM in Germany. Improved treatment response was associated with lower costs and reduced hospitalizations.
MOESM1 of Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study
Creators: name: Denholm, Rachel
name: Werf, Esther
name: Hay, Alastair
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Appendix 1. Acute lower respiratory tract infection medical codes. Appendix 2. Asthma status medical codes. Appendix 3. Asthma status treatment product codes. Appendix 4. Description of conditions and definitions of chronic conditions included in the multimorbidity score. Appendix 5. Episode and measures of practice variance in medication prescribed within three days of ALRTIa diagnosis. Appendix 6. Sensitivity analysis: multivariate final models investigating factors associated with an antibiotic prescription or change in asthma medication within three days of an ALRTIa episode, stratified by asthma statusb and restricted to patients first ALRTI infection in the study period.
ProDyn0: Inferring calponin homology domain stretching behavior using graph neural networks
Creators: name: Madani, Ali
name: Shirazinejad, Cyna
name: Ong, Jia Rui
name: Shams, Hengameh
name: Mofrad, Mohammad
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Machine Learning (cs.LG)
subject: FOS: Biological sciences
subject: FOS: Computer and information sciences

description: Graph neural networks are a quickly emerging field for non-Euclidean data that leverage the inherent graphical structure to predict node, edge, and global-level properties of a system. Protein properties can not easily be understood as a simple sum of their parts (i.e. amino acids), therefore, understanding their dynamical properties in the context of graphs is attractive for revealing how perturbations to their structure can affect their global function. To tackle this problem, we generate a database of 2020 mutated calponin homology (CH) domains undergoing large-scale separation in molecular dynamics. To predict the mechanosensitive force response, we develop neural message passing networks and residual gated graph convnets which predict the protein dependent force separation at 86.63 percent, 81.59 kJ/mol/nm MAE, 76.99 psec MAE for force mode classification, max force magnitude, max force time respectively-- significantly better than non-graph-based deep learning techniques. Towards uniting geometric learning techniques and biophysical observables, we premiere our simulation database as a benchmark dataset for further development/evaluation of graph neural network architectures.
description: 8 pages, 2 figures, 2 tables
title: Alterazione della fosfodiesterasi 1B nei neuroni striatali di ratto dopo denervazione dopaminergica: possibile ruolo nei disturbi del movimento
title: PDE1B alterations in rat striatal neurons following dopaminergic denervation: a possible role in movement disorders
titleType: AlternativeTitle
Creators: name: D'ANGELO, VINCENZA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: 6-OHDA; immunohistochemistry; 6 idrossidopamina; PDE1B; Fosfodiesterasi1B; ChAT; PV; parvalbumina; NOS; ossido nitrico sintetasi; CALB; calbindina; ENK; enkefalina; SP; sostanza P; striato; imunoistochimica; 6- hydroxydopamine; phosphodiesterase1B; choline acetyl transferase; nitric oxide synthetase; enkphalin; substance P
subject: 6-OHDA
subject: immunohistochemistry
subject: 6 idrossidopamina
subject: PDE1B
subject: Fosfodiesterasi1B
subject: ChAT
subject: PV
subject: parvalbumina
subject: NOS
subject: ossido nitrico sintetasi
subject: CALB
subject: calbindina
subject: ENK
subject: enkefalina
subject: SP
subject: sostanza P
subject: striato
subject: imunoistochimica
subject: 6- hydroxydopamine
subject: phosphodiesterase1B
subject: choline acetyl transferase
subject: nitric oxide synthetase
subject: enkphalin
subject: substance P

description: 20. ciclo
description: 1. INTRODUZIONE - 1.1 Cenni sulla traduzione del segnale: i secondi messaggeri - 1.2 Nucleotidi ciclici - 1.3 Le fosfodiesterasi - 1.4 Le PDE 1 - 1.5 La PDE1B. - 2. Scopo della ricerca. - 3. Materiali e metodi - 3.1 Chirurgia - 3.2 Omogenizzazione dei campioni - 3.3 Determinazione delle proteine - 3.4 Elettroforesi - 3.5 Western Blot - 3.6 Saggio di attività Fosfodiesterasica - 3.7 Saggio immunoenzimatico (EIA) - 3.8 Immunoistochimica, Immunofluorescenza e Doppia Marcatura - 3.9 Analisi morfometrica e statistica. - 4. Risultati - 4.1 Deafferentazione Dopaminergica - 4.2 Assay biochimici - 4.3 Immunoistochimica della PDE1B - 4.4 Immunofluorescenza e colocalizzazione PDE1B e CALB, ENK, SP, ChAT, PV, NOS - 4.5 Statistica. - 5. Discussione. - 6. Appendice: I fenotipi cellulari dello striato. - 7. Bibliografia
Influence of stress on incipient karst generation in natural fracture networks
Creators: name: Wang, Xiaoguang
name: Aliouache, Mohammed
name: Lei, Qinghua
name: Jourde, Hervé
Publisher: name: ETH Zurich
Year: 2019

description: Geophysical Research Abstracts, 21
description: ISSN:1029-7006
description: ISSN:1607-7962
VALORAÇÃO CONTINGENTE DA ÁREA DE PROTEÇÃO AMBIENTAL (APA) SÃO JOSÉ – MG: UM ESTUDO DE CASO
Creators: name: Cirino, Jader Fernandes
name: De Lima, Joao Eustaquio
name: Cirino, Jader Fernandes
name: De Lima, Joao Eustaquio
Publisher: name: Unknown
Year: 2006
Subjects: subject: Environmental Economics and Policy
subject: Resource /Energy Economics and Policy
subject: APA São José
subject: valoração contingente
subject: disposição a pagar
subject: gestão ambiental
subject: economia dos recursos naturais

description: A Área de Proteção Ambiental (APA) São José – MG apresenta um rico patrimônio natural e histórico. Apesar de tal fato e de ser uma área de proteção desde 1981, vem sofrendo na atualidade com degradações ambientais. Dentro desse contexto, emergiu a questão de se valorar a APA São José com o objetivo de fornecer subsídios para a elaboração e consecução de políticas públicas e de projetos públicos e privados de conservação ou exploração sustentável do referido ativo. Como método de valoração, utilizou-se a valoração contingente, por meio da abordagem de HANEMANN (1984) e do método do bootstrapping, para obter uma disposição a pagar (DAP) mensal individual por habitante dos cinco municípios que compreendem a APA São José de R$22,88, com um desvio-padrão relativamente baixo de R$3,25. Quanto à confiabilidade da medida estimada, destaca-se a preocupação do presente trabalho em adotar procedimentos visando evitar ou minimizar os vieses que geralmente ocorrem em pesquisas de valoração ambiental.
$Σ_cN$ interaction in chiral perturbation theory
Creators: name: Meng, Lu
name: Wang, Bo
name: Zhu, Shi-Lin
Publisher: name: arXiv
Year: 2019
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We adopt the heavy baryon chiral perturbation theory to calculate the $Σ_cN$ interaction to the next-to-leading order. We consider the contact interactions, one-pion-exchange contributions, two-pion-exchange diagrams, and renormalization effects of the vertices, masses and wave functions. With the pion mass dependent expression, we fit the $Σ_cN$ interaction from HAL QCD calculation with $m_π\approx 410$ MeV and $m_π\approx 570$ MeV, and then extrapolate it to the physical pion mass. The $^3S_1(I=1/2)$ $Σ_{c}N$ interaction is weakly attractive but no bound solution is found. We also propose a quark model to estimate the leading order $Σ_cN$ contact interaction with the $NN$ interaction as input. This approach combining the quark model and the chiral effective field theory predicts a very attractive interaction in $^1S_0(I=3/2)$ $Σ_{c}N$ channel and a two-body bound state.
description: 11 pages, 9 figures
Chlorochroa viridicata
Creators: name: Rider, David A.
name: Swanson, Daniel R.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Chlorochroa
Chlorochroa viridicata

description: Chlorochroa viridicata (Walker, 1867)
 Distribution: Canada: AB. United States: AZ (Wheeler 2018), CA (Wheeler 2018), CO, KS (Wheeler 2018), LA (Wheeler 2018), MT, NE, ND (Rider 2012), NM, OK (Arnold & Drew 1988), SD (Thomas 1983), TX (Wheeler 2018), WY (Lavigne & Pfadt 1965). (Mexico)
 Comments: Wheeler (2018) recently studied the biology and distribution of this species. This species is considered to be a member of the subgenus Rhytidolomia.
description: Published as part of Rider, David A. & Swanson, Daniel R., 2021, A distributional synopsis of the Pentatomidae (Heteroptera) north of Mexico, including new state and provincial records, pp. 1-69 in Zootaxa 5015 (1) on page 36, DOI: 10.11646/zootaxa.5015.1.1, http://zenodo.org/record/5159085
Budget impact of capmatinib for adults with metastatic non-small cell lung cancer harboring a MET exon 14 skipping mutation in the United States
Creators: name: Beilei Cai
name: Zhou, Zheng-Yi
name: Weiguang Xue
name: Hazra, Nisha C.
name: Singh, Mukesh
name: Mishra, Dinesh
name: Brixner, Diana
name: Oderda, Gary
name: Biskupiak, Joseph
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: To estimate the budget impact of adding capmatinib, the first FDA approved MET inhibitor, to a US commercial or Medicare health plan for patients with metastatic non-small cell lung cancer (mNSCLC) whose tumors have a mutation that leads to MET exon 14 (METex14) skipping. Target population size was estimated using published epidemiology data. Clinical data were obtained from the GEOMETRY mono-1 capmatinib trial and published trials. Treatments in the market mix included crizotinib, pembrolizumab, ramucirumab, and chemotherapy. Uptake of capmatinib and testing rates were based on market research. All costs (drug acquisition and administration, pre-progression, progression, terminal care, adverse event, and testing) were estimated based on public sources (2020 USD). The number of patients eligible for capmatinib in the first three years was estimated to be 2–3 in a hypothetical 1 million member commercial plan and 34–44 in a hypothetical 1 million member Medicare plan each year. The estimated total budget impact ranged from $9,695 to $67,725 for a commercial plan and $141,350 to $985,695 for Medicare. With capmatinib included, a marginal per member per month budget impact was estimated (commercial: $0.0008 to $0.0056; Medicare: $0.0118 to $0.0821). Capmatinib inclusion resulted in lower medical costs (commercial: –$0.0003 to –$0.0007; Medicare: –$0.0037 to –$0.0106), partially offsetting increased drug costs ($0.0011 to $0.0064; $0.0154 to $0.0928, respectively), and were primarily driven by reductions in progression and terminal care costs (–$0.0003 to –$0.0009; –$0.0037 to –$0.0125, respectively). The results were most sensitive to capmatinib market share, capmatinib price, and treatment duration. Certain assumptions were applied to the model to account for inputs with limited evidence. The estimated budget impact of including capmatinib for mNSCLC with a METex14 skipping mutation is minimal, and the increased drug costs were partially offset by savings in AEs, and progression-related and terminal care costs.
Adriano Olivetti’s Vision to Merge Design and Economy: Design Consultants vis-à-vis Reproducibility as a ‘Concrete Utopia’
Creators: name: Charitonidou, Marianna
Publisher: name: ETH Zurich
Year: 2019
Subjects: design history

description: The Cost of Design 2019, Annual Conference of the Design History Society, Northumbria University, 7th – 9 th September, Book of Abstracts
Spontaneous Magnetization and Electron Momentum Density in 3D Quantum Dots
Creators: name: Saniz, R.
name: Barbiellini, B.
name: Denison, A. B.
name: Bansil, A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We discuss an exactly solvable model Hamiltonian for describing the interacting electron gas in a quantum dot. Results for a spherical square well confining potential are presented. The ground state is found to exhibit striking oscillations in spin polarization with dot radius at a fixed electron density. These oscillations are shown to induce characteristic signatures in the momentum density of the electron gas, providing a novel route for direct experimental observation of the dot magnetization via spectroscopies sensitive to the electron momentum density.
description: 5 pages (Revtex4), 4 (eps) figures
Universal bounds on the size of a black hole
Creators: name: Yang, Run-Qiu
name: Lu, H.
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: For static black holes in Einstein gravity, if matter fields satisfy a few general conditions, we conjecture that three characteristic parameters about the spatial size of black holes, namely the outermost photon sphere area $A_{\mathrm{ph,out}}$, the corresponding shadow area $A_{\mathrm{sh,out}}$ and the horizon area $A_{\mathcal{H}}$ satisfy a series of universal inequalities $9A_{\mathcal{H}}/4\leq A_{\mathrm{ph,out}}\leq A_{\mathrm{sh,out}}/3\leq 36πM^2$, where $M$ is the ADM mass. We present a complete proof in the spherically symmetric case and some pieces of evidence to support it in general static cases. We also discuss the properties of the photon spheres in general static spacetimes and show that, similar to horizon, photon spheres are also conformal invariant structures of the spacetimes.
description: Match the published version
Additional file 1 of Identification of two novel lipid metabolism-related long non-coding RNAs (SNHG17 and LINC00837) as potential signatures for osteosarcoma prognosis and precise treatment
Creators: name: Tang, Zhifang
name: Feng, Hanzhen
name: Shu, Longjun
name: Guo, Minzheng
name: Qi, Baochuang
name: Pu, Luqiao
name: Shi, Hongxin
name: Ren, Junxiao
name: Li, Chuan
Publisher: name: figshare
Year: 2023
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Pharmacology
Biological Sciences not elsewhere classified
Cancer
Hematology
Virology

description: Supplementary Material 1
BO'LINISH BELGILARI: SONLARNING UMUMIY BO'LUVCHISI VA KARRALISI
Creators: name: Meyliyev, Jasurbek
Publisher: name: Zenodo
Year: 2025

description: Mazkur maqolada bo‘linish belgilari, sonlarning umumiy bo‘luvchisi va umumiy karralisi tushunchalari matematik nuqtayi nazardan yoritilgan. Unda sonlarning umumiy bo‘luvchisi va umumiy karralisini aniqlash usullari, ularning xususiyatlari hamda real hayotdagi amaliy qo‘llanilishi keng tahlil qilingan. Shuningdek, maqolada Evklid algoritmi, asosiy sonlar va ularning o‘zaro bog‘liqligi kabi mavzular ham qamrab olingan. Ushbu ish bo‘linish belgilarining nazariy va amaliy ahamiyatini o‘quvchilarga yetkazish, matematik ko‘nikmalarni rivojlantirishga qaratilgan.
AS EXPORTAÇÕES E A COMPETITIVIDADE DO COMPLEXO CAFEEIRO BRASILEIRO E PARANAENSE
Creators: name: Sereia, Vanderlei Jose
name: Da Camara, Marcia Regina Gabardo
name: Cintra, Marcela Vasques
name: Sereia, Vanderlei Jose
name: Da Camara, Marcia Regina Gabardo
name: Cintra, Marcela Vasques
Publisher: name: Unknown
Year: 2006
Subjects: subject: Crop Production/Industries
subject: International Development
subject: International Relations/Trade
subject: Comércio Internacional
subject: Competitividade
subject: Complexo Cafeeiro
subject: Constant-Market-Share

description: O objetivo deste artigo é analisar os determinantes da competitividade das exportações do complexo cafeeiro paranaense entre 1990 e 2003. O estudo pretende sistematizar: a literatura recente sobre o tema, enfocando a competitividade de um dos principais produtos da pauta de exportações brasileira e do Paraná. Realizou-se a revisão crítica da literatura das teorias do comércio internacional e da competitividade e em seguida, caracterizou-se a dinâmica do complexo cafeeiro do brasileiro e paranaense. O artigo identifica as vantagens competitivas do café paranaense (verde, torrado, solúvel e especial) em relação aos países concorrentes; discute as barreiras às importações impostas ao café brasileiro pelos países importadores; e finaliza com as possíveis políticas públicas e privadas favoráveis à competitividade das exportações de café.
MOESM2 of Genetic diversity of a widespread annual killifish from coastal Tanzania
Creators: name: Bartáková, Veronika
name: Nagy, Béla
name: Polačik, Matej
name: Blažek, Radim
name: Hieromin Lamtane
name: Reichard, Martin
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Additional file 2: Additional figures supplementing results. Figure S1. Bayesian reconstruction of mitochondrial phylogeny of the N. melanospilus species complex based on 83 ingroup and 1 outgroup haplotypes of the 657 bp fragment of mitochondrial gene COI, including identity of individual samples. Bayesian inference posterior probabilities from MrBayes 3.2.6 are shown for each node. Figure S2. Correlation between Ln (distance) and linearized pairwise FSTENA values (FST/(1 − FST)) tested by the Mantel tests (1000 permutations) analysed in GENEPOP. Figure S3. Mismatch distribution for two widespread mtDNA lineages. Dashed lines connect observed values and solid lines show the expected distribution under a demographic expansion model
Additional file 1 of Association of IL-10 (− 1082 A/G) and IL-6 (− 174 G/C) gene polymorphism with type 2 diabetes mellitus in Ethiopia population
Creators: name: Ayelign, Birhanu
name: Negash, Markos
name: Henok Andualem
name: Tadelo Wondemagegn
name: Eyuel Kassa
name: Tewodros Shibabaw
name: Yonas Akalu
name: Meseret Derbew Molla
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Questionnaire (English version).
Nonparametric Inference of Neutron Star Composition, Equation of State, and Maximum Mass with GW170817
Creators: name: Essick, Reed
name: Landry, Philippe
name: Holz, Daniel E.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The detection of GW170817 in gravitational waves provides unprecedented constraints on the equation of state (EOS) of the ultra-dense matter within the cores of neutron stars (NSs). We extend the nonparametric analysis first introduced in Landry & Essick (2019), and confirm that GW170817 favors soft EOSs. We infer macroscopic observables for a canonical 1.4 $M_{\odot}$ NS, including the tidal deformability $Λ_{1.4} = 211^{+312}_{-137}$ ($491^{+216}_{-181}$) and radius $R_{1.4}= 10.86^{+2.04}_{-1.42}$ ($12.51^{+1.00}_{-0.88}$) km, as well as the maximum mass for nonrotating NSs, $M_{max} = 2.064^{+0.260}_{-1.34}$ ($2.017^{0.238}_{-0.087}$) $M_\odot$, with nonparametric priors loosely (tightly) constrained to resemble candidate EOSs from the literature. Furthermore, we find weak evidence that GW170817 involved at least one NS based on gravitational-wave data alone ($B^{NS}_{BBH}= 3.3 \pm 1.4$), consistent with the observation of electromagnetic counterparts. We also investigate GW170817's implications for the maximum spin frequency of millisecond pulsars, and find that the fastest known pulsar is spinning at more than 50% of its breakup frequency at 90% confidence. We additionally find modest evidence in favor of quark matter within NSs, and GW170817 favors the presence of at least one disconnected hybrid star branch in the mass--radius relation over a single stable branch by a factor of 2. Assuming there are multiple stable branches, we find a suggestive posterior preference for a sharp softening around nuclear density followed by stiffening around twice nuclear density, consistent with a strong first-order phase transition. While the statistical evidence in favor of new physics within NS cores remains tenuous with GW170817 alone, these tantalizing hints reemphasize the promise of gravitational waves for constraining the supranuclear EOS.
description: 23 pages, 7 figures, 10 tables
Partially quenched chiral perturbation theory and numerical simulations
Creators: name: Q Collaboration
name: Farchioni, F.
name: Gebert, C.
name: Montvay, I.
name: Scholz, E.
name: Scorzato, L.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The dependence of the pseudoscalar meson mass and decay constant is compared to one-loop Partially Quenched Chiral Perturbation Theory (PQChPT) in a numerical simulation with two light dynamical quarks. The characteristic behaviour with chiral logarithms is observed. The values of the fitted PQChPT-parameters are in a range close to the expectation in continuum in spite of the fact that the lattice spacing is still large, namely a=0.28 fm.
description: 11 pages, 3 figures; discussion of the results in section 3 extended
Association between infliximab concentrations and clinical response in psoriasis: a prospective cohort study
Creators: name: M. Colls-Gonzalez
name: J. Notario-Rosa
name: J. Bas-Minguet
name: A. Padullés-Zamora
name: F. Morandeira-Rego
name: F. Valentí-Medina
name: H. Colom-Codina
name: N. Padullés-Zamora
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Infliximab (IFX) trough concentrations (Cmin) have been linked to treatment efficacy in psoriatic patients. Inter-individual IFX Cmin variability and factors influencing IFX pharmacokinetics could explain differences in treatment response. To evaluate the association between IFX Cmin and clinical outcomes in psoriatic patients. Prospective study of 33 patients with moderate to severe psoriasis receiving IFX at Bellvitge University Hospital, between October 2013 and November 2016. IFX Cmin and antibodies toward infliximab (ATI) were measured. We collected 155 IFX Cmin and ATI values (mean age, 46 (14) years; 11 (33.3%) women). Mean IFX Cmin was 2.5 (2.4) mg/L and ATIs were detected in six patients, resulting in undetectable IFX Cmin. IFX Cmin was significantly associated with ATI and body mass index (BMI) (β −2.51, 95% CI −3.56 to −1.4 and β −0.05, 95% CI −0.09 to −0.01). PASI score and PASI 90/100 response were significantly associated with IFX Cmin (IRR 0.80, 95% CI 0.70 to 0.92; OR 1.79, 95% CI 1.18 to 2.71 and OR 1.79, 95% CI 1.14 to 2.81). IFX Cmin significantly influences PASI 90/100 response rates. IFX Cmin wa significantly associated with ATI and BMI. The observed inter-individual variability in IFX Cmin supports the need for IFX drug monitoring.
An ASKAP survey for HI absorption towards dust-obscured quasars
Creators: name: Glowacki, M.
name: Allison, J. R.
name: Moss, V. A.
name: Mahony, E. K.
name: Sadler, E. M.
name: Callingham, J. R.
name: Ellison, S. L.
name: Whiting, M. T.
name: Bunton, J. D.
name: Chippendale, A. P.
name: Heywood, I.
name: McConnell, D.
name: Raja, W.
name: Voronkov, M. A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Obscuration of quasars by accreted gas and dust, or dusty intervening galaxies, can cause active galactic nuclei (AGN) to be missed in optically-selected surveys. Radio observations can overcome this dust bias. In particular, radio surveys searching for HI absorption inform us on how the AGN can impact on the cold neutral gas medium within the host galaxy, or the population of intervening galaxies through the observed line of sight gas kinematics. We present the results of a HI absorption line survey at $0.4 < z < 1$ towards 34 obscured quasars with the Australian SKA Pathfinder (ASKAP) commissioning array. We detect three HI absorption lines, with one of these systems previously unknown. Through optical follow-up for two sources, we find that in all detections the HI gas is associated with the AGN, and hence that these AGN are obscured by material within their host galaxies. Most of our sample are compact, and in addition, are either gigahertz peaked spectrum (GPS), or steep spectrum (CSS) sources, both thought to represent young or recently re-triggered radio AGN. The radio spectral energy distribution classifications for our sample agree with galaxy evolution models in which the obscured AGN has only recently become active. Our associated HI detection rate for GPS and compact SS sources matches those of other surveys towards such sources. We also find shallow and asymmetric HI absorption features, which agrees with previous findings that the cold neutral medium in compact radio galaxies is typically kinematically disturbed by the AGN.
description: Accepted for publication in MNRAS. 19 pages, 8 figures
Axion Star Nucleation in Dark Minihalos around Primordial Black Holes
Creators: name: Hertzberg, Mark P.
name: Schiappacasse, Enrico D.
name: Yanagida, Tsutomu T.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider a general class of axion models, including the QCD and string axion, in which the PQ symmetry is broken before or during inflation. Assuming the axion is the dominant component of the dark matter, we discuss axion star formation in virialized dark minihalos around primordial black holes through gravitational Bose-Einstein condensation. We determine the conditions for minihalos to kinetically produce axion stars before galaxy formation. Today, we expect up to $\sim 10^{17}$ ($\sim 10^9$) axion stars in a radius of 100 parsecs around the Sun for the case of the QCD (string) axion.
description: 7 pages, 3 figures. v2: updated towards version accepted in Physical Review D. v3: Some typos corrected
Umsetzung von Open Access an der ETH Zürich am Beispiel des Bildarchivs der ETH-Bibliothek
Creators: name: Graf, Nicole
Publisher: name: ETH Zurich
Year: 2009
Subjects: BILDARCHIVE, BILDSAMMLUNGEN
OPEN ACCESS (WISSENSCHAFTLICHES PUBLIZIEREN)
Google Bildersuche

description: Im März 2006 hat die ETH Zürich die Berliner Erklärung über den offenen Zugang zu wissenschaftlichem Wissen unterzeichnet, und im Juli 2008 wurde die Open-Access-Policy verabschiedet, in der alle Wissenschaftler/innen aufgefordert werden, aktiv bei der Umsetzung mitzuwirken. Zentrale Instrumente für die Umsetzung von Open Access sind für die Wissenschaftler die ETH E-Collection (das Institutional Repository der ETH Zürich), in der u.a. Post Prints und Dissertationen gesammelt und veröffentlicht werden. Die ETH-Bibliothek ihrerseits bietet unterdessen weitere Inhalte als Open-Access-Angebote an: SEALS, eine kooperative Plattform für retrodigitalisierte Zeitschriften, Videos von Einführungs- und Abschiedsvorlesungen von ETH-Professor/innen als Podcasts, die Schulratsprotokolle, ausgewählte alte Landkarten und alte Drucke. Im Rahmen von e-rara als neuestem Kooperationsprojekt von Schweizer Hochschulbibliotheken sollen in den nächsten drei Jahren 15’000 ältere Schweizer Drucke digitalisiert und online angeboten werden. Das Bildarchiv der ETH-Bibliothek hat einen Bestand von über 1,3 Mio. Bildern (Schwerpunkt Fotografien aus dem 20. Jahrhundert), davon sind rund 90‘000 Bilder digitalisiert und teilweise über die Datenbank BildarchivOnline recherchierbar. Im Herbst 2008 wurden mit dem Release E-Pics 2.0 neue Features wie erweiterte Personalisierung, Bestellvorgang, Direkt-Download, Powerpoint-Export und PDF-Druckvorlagen eingeführt und gleichzeitig die Vor-aussetzung für die Umsetzung von Open Access für das Bildarchiv geschaffen. Das bisher als Bildagentur organisierte Bildarchiv hat seine kostenpflichtigen Geschäftsgänge teilweise angepasst und überlässt beispielsweise ihre Bildbestände den Wissenschaftler/innen fortan kostenlos. Zudem wurde als Lizenzierungsmodell Creative Commons für die Bildbestände der ETH-Bibliothek eingeführt.
Condominium Housing in Addis Ababa: Urban Commons as a Bridge between the Spatial and the Social
Creators: name: Charitonidou, Marianna
Publisher: name: ETH Zurich
Year: 2020

description: A point of departure of this paper is the hypothesis that the quotidian practices of communities and their socio-economic and cultural characteristics are interconnected with the spatial attributes of co-housing practices. The paper focuses on the examination of the collaboration of the Ethiopian government collaborated with the German Technical Cooperation (GTZ) that intended to address the issues related to the mass housing program in Addis Ababa. Special attention is paid to the so-called “UN-Habitat”, a Human Settlements programme of the United Nations established in 1978 aiming to enhance the urban future. In 2005, the City Administration of Addis Ababa initiated a large-scale housing development project in order to address urban poverty and improve the living conditions of low and middle-income residents. To grasp the specificity of the Ethiopian context, one should bear in mind that in 2014 only 20.7% of Ethiopian residents lived in urban settlements as a report of the United Nations published that same year informs us.
Departing from the fact that from 2006 to 2016 the area of condominium housing has increased to occupy 11% of the area of the city of Addis Ababa (fig. 1), the paper examines the tensions between universal aspirations and local realities in the case of Ethiopia’s most ambitions mass housing scheme, which is ‘Addis Ababa Grand Housing Program’ (AAGHP) and was launched in 2004. This program was integrated in the ‘Integrated Housing Development Program’ (IHDP) in 2006. The particularity of the urban redevelopment of Addis Ababa lies in the fact that, in contrast with the majority of the “new city” approaches, it incorporated and permitted the construction of low-income housing thanks to the IHDP, which contributed significantly to the acceleration of the production of social housing in Ethiopia. My objective is to shed light on the common codes and conventions characterising the production of condominium housing in Addis Ababa, on the one hand, and to render explicit how the fact that space-as-commons functions a set of social relations which potentially challenges the very foundations of ownership becomes evident in the case of urban redevelopment of Addis Ababa, on the other hand.
Cyptocephala elegans
Creators: name: Rider, David A.
name: Swanson, Daniel R.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Cyptocephala
Cyptocephala elegans

description: Cyptocephala elegans (Malloch, 1919)
 Distribution: United States: FL, TX.
description: Published as part of Rider, David A. & Swanson, Daniel R., 2021, A distributional synopsis of the Pentatomidae (Heteroptera) north of Mexico, including new state and provincial records, pp. 1-69 in Zootaxa 5015 (1) on page 37, DOI: 10.11646/zootaxa.5015.1.1, http://zenodo.org/record/5159085
Dose–response association between vitamin D deficiency and atopic dermatitis in children, and effect modification by gender: a case-control study
Creators: name: Mohamed, Amal Ahmed
name: Ahmed, Eman Mohamed Salah
name: Farag, Youssef M. K.
name: Nermeen Ibrahim Bedair
name: Nourelhuda Ahmed Nassar
name: Ayat Ibrahim Mohamed Ghanem
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Vitamin D is a regulatory factor for immunity and skin barrier functions. It is hypothesized to be linked to atopic dermatitis (AD) which is characterized by interaction between epidermal barrier dysfunction and dysregulation of skin immune functions. One hundred AD patients and one hundred and one normal controls were collected from outpatient clinic based on their clinical condition, both had measurement of 25-hydroxyvitamin D [25(OH)D]. We assessed the relationship between 25(OH)D deficiency and AD prevalence using adjusted Poisson regression model. Serum 25(OH)D levels were significantly lower in cases than controls (mean 35.1 versus 22.6 ng/mL, p p-interaction In this case-control study in children, we found a statistically significant dose–response association between vitamin D deficiency and AD. We also observed a statistically significant effect modification of this association by gender. Further research is recommended to study this association longitudinally, and to examine whether treating vitamin D deficiency may potentially improve AD.Key pointsQuestion: Can atopic dermatitis be associated with vitamin D deficiency?Finding: Serum 25(OH)D levels were significantly lower in cases with AD than in controls. Prevalence ratios for comparing male participants with intermediate and deficient vitamin D levels to those with optimal levels were 3.38 (1.21, 9.40) and 5.20 (1.91, 14.13), respectively, whereas in the female participants were 1.32 (0.96, 1.83) and 1.49 (1.04, 2.14), respectively (p-interaction Meaning: vitamin D deficiency is associated with AD in children, effect modification of this association by gender was also observed. Question: Can atopic dermatitis be associated with vitamin D deficiency? Finding: Serum 25(OH)D levels were significantly lower in cases with AD than in controls. Prevalence ratios for comparing male participants with intermediate and deficient vitamin D levels to those with optimal levels were 3.38 (1.21, 9.40) and 5.20 (1.91, 14.13), respectively, whereas in the female participants were 1.32 (0.96, 1.83) and 1.49 (1.04, 2.14), respectively (p-interaction Meaning: vitamin D deficiency is associated with AD in children, effect modification of this association by gender was also observed.
Excitations in confined helium
Creators: name: Apaja, V.
name: Krotscheck, E.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We design models for helium in matrices like aerogel, Vycor or Geltech from a manifestly microscopic point of view. For that purpose, we calculate the dynamic structure function of 4He on Si substrates and between two Si walls as a function of energy, momentum transfer, and the scattering angle. The angle--averaged results are in good agreement with the neutron scattering data; the remaining differences can be attributed to the simplified model used here for the complex pore structure of the materials. A focus of the present work is the detailed identification of coexisting layer modes and bulk--like excitations, and, in the case of thick films, ripplon excitations. Involving essentially two--dimensional motion of atoms, the layer modes are sensitive to the scattering angle.
description: Phys. Rev. B (2003, in press)
Tepa brevis
Creators: name: Rider, David A.
name: Swanson, Daniel R.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Tepa
Tepa brevis

description: Tepa brevis (Van Duzee, 1904)
 Distribution: United States: AZ, CA, CO, ID, ND (Rider 2012), NM, NV, OR, SD (Parshley 1922), TX, UT. (Mexico)
description: Published as part of Rider, David A. & Swanson, Daniel R., 2021, A distributional synopsis of the Pentatomidae (Heteroptera) north of Mexico, including new state and provincial records, pp. 1-69 in Zootaxa 5015 (1) on page 37, DOI: 10.11646/zootaxa.5015.1.1, http://zenodo.org/record/5159085
SIMULAÇÃO DE CENÁRIOS PARA A PECUÁRIA LEITEIRA DE ECONOMIA FAMILIAR EM MINAS GERAIS
Creators: name: Leite, Jose Luiz Bellini
name: Resende, Humberto
name: Leite, Jose Luiz Bellini
name: Resende, Humberto
Publisher: name: Unknown
Year: 2006
Subjects: subject: Livestock Production/Industries
subject: modelagem matemática
subject: produção de leite
subject: sistemas bioeconômicos
subject: agricultura familiar.

description: Apresenta-se a adaptação e os resultados de uma aplicação de modelo de sistema bioeconômico de produção com ênfase na pecuária leiteira de economia familiar em Minas Gerais. O modelo baseado em Leite (2000 e 2005) oferece flexibilidade para simular cenários para sistemas especializados de produção de leite, produção de leite e carne e consorciação lavoura–pecuária. Sua função objetivo é a maximização da renda que é utilizada na verificação de quatro hipóteses (a) diferente tecnologia pode aumentar a renda (eficiência técnica); (b) diferente alocação de recursos pode elevar a renda (eficiência alocativa); (c) integração lavoura–pecuária pode melhorar a renda (diversificação versus especialização) e (d) o conjunto das hipóteses acima pode melhorar a renda. O modelo foi aplicado utilizando informações de 55 fazendas da microrregião de Juiz de Fora na Zona da Mata de Minas Gerais. Os resultados mostraram que, na comparação com os resultados econômicos existentes na região de estudos, todas as hipóteses são verificadas, ou seja, permitem a melhoria da renda dos produtores. Mostrou ainda que considerando à aptidão das terras da região e sua otimização a pecuária leiteira não teria condições de concorrer com a fruticultura.
MOESM1 of Peer-support to increase uptake of screening for diabetic retinopathy: process evaluation of the DURE cluster randomized trial
Creators: name: Nyawira Mwangi
name: Covadonga Bascaran
name: Ramke, Jacqueline
name: Kipturgo, Mathew
name: Kim, Min
name: Ng’ang’a, Mark
name: Gichuhi, Stephen
name: Mutie, Dorothy
name: Moorman, Consuela
name: Muthami, Lawrence
name: Foster, Allen
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Plant Biology
subject: Computational Biology

description: Additional file 1. Methodology for development of training for peer supporters
BRAHMS results in the context of saturation and quantum evolution
Creators: name: Debbe, R.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We report BRAHMS results from RHIC d+Au and p+p collisions at Sqrt(s_NN)=200GeV. A remarkable change in the nuclear modification factor RdAu is seen as the pseudorapidity of the detected charged hadrons changes from zero at mid-rapidity to 3.2 at the most forward angle studied during the 2003 run. For pseudorapidity eta>1 the suppression of the Rcp factor is more pronounced in the sample of central events in contrast to the behavior at mid-rapidity where the central events show higher enhancement compared to the semi-central sample. These results are consistent with a saturated Au wave function strongly affected by quantum evolution at higher values of rapidity.
description: 7 pages, 3 figures to be published in the Proceedings of the 20th Winter Workshop on Nuclear Dynamics, Trelawny Beach, Jamaica
Additional file 1 of Online health information-seeking behaviors and skills of Chinese college students
Creators: name: Dangui Zhang
name: Weixin Zhan
name: Chunwen Zheng
name: Jinsheng Zhang
name: Anqi Huang
name: Hu, Shuan
name: Ba-Thein, William
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Questionnaire: Online Health Information-seeking behaviors.
Additional file 8 of Identification of two novel lipid metabolism-related long non-coding RNAs (SNHG17 and LINC00837) as potential signatures for osteosarcoma prognosis and precise treatment
Creators: name: Tang, Zhifang
name: Feng, Hanzhen
name: Shu, Longjun
name: Guo, Minzheng
name: Qi, Baochuang
name: Pu, Luqiao
name: Shi, Hongxin
name: Ren, Junxiao
name: Li, Chuan
Publisher: name: figshare
Year: 2023
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Pharmacology
Biological Sciences not elsewhere classified
Cancer
Hematology
Virology

description: Supplementary Material 8
ISSUES IN THE ECONOMIC DEVELOPMENT AND UTILIZATION OF EU FUNDS IN A DISADVANTAGED SUB-REGION OF THE SOUTHERN GREAT PLAIN REGION
Creators: name: Horvath, Peter
name: Horvath, Peter
Publisher: name: Unknown
Year: 2013
Subjects: subject: Community/Rural/Urban Development
subject: sub-statistical regions
subject: EU sources
subject: Southern Great Plain
subject: cluster-analysis

description: The development period between 2007 and 2013 had a historical significance for Hungary as the funds that were provided by the European Union and were supplemented by the domestic and public sectors naturally offered great possibilities for the country’s sub-statistical regions and regions to inspire their development and innovation. In order to use these funds efficiently it is essential to incorporate the developments into the area’s capabilities, to harmonize them and to increase the role of the sub-statistical regions and regions. This study ranks the sub-regions of the Southern Great Plain Region in terms of their economic characteristics and identifies the most disadvantageous ones. Using as an example a specific sub-region it determines the local effects of EU payments with the application of different statistical methods.
Tepa vanduzeei Rider 1986
Creators: name: Rider, David A.
name: Swanson, Daniel R.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Tepa
Tepa vanduzeei

description: Tepa vanduzeei Rider, 1986b
 Distribution: United States: AZ, CA, CO, ID (Harris & Shull 1944), KS, MO, NE, NM, NV (Rider 1986b), OK, SD, TX, UT (Van Duzee 1917, Knowlton & Harmston 1940). (Mexico)
 Comments: See comments under Tepa rugulosa.
description: Published as part of Rider, David A. & Swanson, Daniel R., 2021, A distributional synopsis of the Pentatomidae (Heteroptera) north of Mexico, including new state and provincial records, pp. 1-69 in Zootaxa 5015 (1) on page 38, DOI: 10.11646/zootaxa.5015.1.1, http://zenodo.org/record/5159085