cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Timing of Breast Cancer Surgery, Menstrual Cycle & Prognosis
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Surgery is the most common treatment for early breast cancer. There may be a particular time during the menstrual cycle when breast cancer surgery is less successful and results in decreased survival. A multi-disciplinary research team consisting of an epidemiologist, reproductive hormone specialist, basic immunologist, and three breast cancer surgeons will evaluate breast cancer patients’ hormonal status to determine whether breast cancer surgery during a particular time of the menstrual cycle known as the follicular phase (i.e., occurring between menstruation and ovulation) will increase the chance that the tumor will re-occur. This three-year study will follow 400 White, African-American, Hispanic, and Asian or Pacific Islander premenopausal women who will undergo surgery for breast cancer at four different hospitals (University of California San Diego, University of California Los Angeles, Los Angeles County-University of Southern California, and USC/Kenneth Norris) between July 1998 and June 2001. Patients with other cancers, or those with a hysterectomy, will not be included in the study. A pathologist will classify the type of breast cancer and where it has spread. The medical and reproductive histories, as well as other important information will be obtained from a detailed telephone interview, medical records, and laboratory results. The phase of the menstrual cycle (i.e., early or late follicular or luteal) will be determined by measuring specific hormones in the urine (e.g., progesterone, estradiol, follicle stimulating hormone, and leutinizing hormone) on a daily basis, starting on the day of surgery, and continuing until the onset of the next menstrual cycle. Most factors that influence the long-term outcome of breast cancer are beyond the doctor's control. This study will work with the body's predictable biologic rhythms (referred to as chronotherapy), in order to search for a better way to treat breast cancer. If the timing of surgical treatment during a particular phase of the menstrual cycle plays a significant role in survival from premenopausal breast cancer, this could possibly extend and/or save a great number of women's lives. In fact, the greatest benefit for timing of surgery would be to those young women at highest risk of breast cancer recurrence. The ease of modifying the timing of breast cancer surgery in the clinical setting could be very rapid and inexpensive; hence, timing of surgery could serve as a potentially simple, but powerful therapeutic tool.
Electrodeposition of Au/Ni nanotubes with highly improved electrochemical performance for non-enzymatic nitrite detection
Creators: name: Wang, Shuyue
name: Yin, Haoyong
name: Qu, Kaige
name: Wang, Ling
name: Gong, Jianying
name: Zhao, Shumin
name: Wu, Shengji
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology

description: Au/Ni nanotubes were fabricated on carbon papers through depositing Au nanoparticles on Ni nanotubes to construct nitrite sensors. The structure and constituent characterisation of Au/Ni-60s NTs demonstrated the homogeneous distribution of Au nanoparticles on the Ni nanotubes. Due to the synergy between Ni nanotubes and Au nanoparticles, highly improved nitrite sensing performance was achieved on Au/Ni-60s NTs, which presented a very wide linear range for nitrite detection. Two linear segments have been obtained in the range of 0.4–40000 µM and 40–130 mM with the detection limit of 0.13 μM. The sensitivity of 707.14 µA·mM−1·cm−2 in lower region and 339.53 µA·mM−1·cm−2 in higher region was achieved. Furthermore, the obtained Au/Ni-60s NTs displayed good selectivity and high reliability for nitrite detection in real samples such as milk and peach juice. This investigation may provide a useful route and reference to construct tubular structures for efficient nitrite detection.
Spatial and seasonal particulate organic carbon cycling within the Delaware estuary, assessed using biomarker and stable carbon isotopic approaches
Creators: name: Hermes, Anna Lauren
Publisher: name: No Publisher Supplied
Year: 2013

description: The fate of terrestrial-derived organic matter (OM) in estuaries is poorly characterized, obscuring the link between carbon cycles of land and sea. This study characterized sources of OM in the Delaware Estuary using multiple organic geochemical analyses: bulk and compound-specific stable carbon isotopes, and n-alkane and phospholipid fatty acid (PLFA) biomarkers. The spatial and temporal variations in particulate organic matter (POM) character in both surface and bottom waters were evaluated for 5 seasonal cruises in 2010-2011. Axial transects were from a marine to a riverine endmember, and geochemical analyses additionally emphasized the estuarine turbidity maxima (ETM), and chlorophyll maxima.   POM characteristics were consistent with previous studies. POM was generally <10% organic carbon (OC) and the δ13C signature of POM became progressively enriched moving downstream, from -26.5 ± 2.3‰ at the riverine endmember to -22.0 ± 1.9‰ at the marine endmember. Yet, mixing of sources in the ETM and spring phytoplankton bloom signatures in Delaware Bay masked the pathway of terrestrial sources.   In contrast, n-alkane and PLFA biomarkers showed the proportion of algal- and terrestrial-derived OM to be comparable in surface waters throughout the estuary and bottom waters were substantially higher in terrestrial and marsh inputs. Bottom water particulates in the ETM comprise the largest suspended OC pool in the estuary, which has a significant terrestrial component and was previously uncharacterized. Biomarker results from this study suggest that the ETM is an effective trap of terrestrial POM.  The δ13C of long chain n-alkanes (C23-C33) confirmed substantial inputs from C4 marsh plant material in both September 2010 (-29.3 ± 0.9‰), and in March 2011 (-31.0 ± 2.1‰). The presence of marsh-derived OM in the main axis of the estuary and ETM suggests that lateral processes are important for OM cycling in estuaries and that the vascular plant derived OM reaching the ocean may not be sourced from upland drainage basins, but from more local inputs such as fringing wetlands. The role of marsh-derived OM in the marine OC cycle demands further attention to fully constrain its reactivity and fate in the marine environment.
Eupyrgota Coquillett 1898
Creators: name: El-Hawagry, Magdi S.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Pyrgotidae
Eupyrgota

description: Genus EUPYRGOTA Coquillett
Eupyrgota Coquillett, 1898: 337. Type species: Eupyrgota luteola Coquillett, 1898, original designation.
Peltodasia Enderlein, 1942: 120. Type species: Peltodasia vespiformis Enderlein, 1942, original designation.
description: Published as part of El-Hawagry, Magdi S., 2017, Catalogue of Egyptian Tephritoidea (Diptera: Schizophora: Acalyptratae), pp. 151-190 in Zootaxa 4299 (2) on page 159, DOI: 10.11646/zootaxa.4299.2.1, http://zenodo.org/record/843233
Reconceiving the State
Creators: name: Heidt-Forsythe, Erin Allyson
Publisher: name: No Publisher Supplied
Year: 2013

description: Assisted reproductive technologies (ARTs), defined as technologies that bring together human gametes for the purposes of reproduction and regenerative research, have enabled new life for those expanding their families, as well as those looking to treat degenerative diseases. As meanings of life have shifted in an era of evolving reproductive technology, the state has new opportunities to intervene, mediate, and prohibit the use of ARTs in the United States. In light of the moral and instrumental ways to understand ARTs and the social implications of ART practices, what is the role of the state in ART oversight? Moreover, how does issue framing of ARTs impact legislative outcomes? Using egg donation as a particular site of morals and markets, I investigate these question through the legislative activity on egg donation at the state level, as well as the public policy making processes about egg donation. Given the empirical and theoretical gaps in ART scholarship about state-level legislation in the US in the contemporary period, this dissertation aims is to answers these research questions through original data on various kinds of ART legislation between 1990 and 2010, at the state level. Employing hazard analysis of egg donation legislation between 1998 and 2008 in 49 states, this project advances the argument that state-level legislative activities on egg donation are vibrant,  and increased by scientific stakeholders in ARTs, as well as the presence of women in politics and economic life. Looking closer at cases of egg donation legislation in case studies of California, New York, Arizona, and Louisiana, I find that legislators frame egg donation as moral and instrumental social issues—with varying degrees of legislative success. I argue that state-level oversight has problematic implications for the concept of stratified reproduction and suggest applying the equal liberty principle to ART policymaking. Finally, I argue that the absence of political debate—particularly the absence of feminist voices—warrants new political solutions to increase democratic discourse on ART issues.
Ocean Acidification: A Research & Training Consortium
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The goal of this UC MRPI proposal is to form a multidisciplinary collaboration to study ocean acidification (OA) and its impacts on the coastal marine ecosystems of California. As the need to forecast the impacts of ocean acidification on marine ecosystems has become more urgent, it is clear that sound science and contributions to strategies will only be found through multidisciplinary collaborations within the broad marine science community. Thus, we propose a consortium to integrate and strengthen our research programs to work on critical questions about how ocean acidification will impact marine communities. In addition, we propose to focus especially on designing and implementing multidisciplinary training for graduate students and postdoctoral fellows, and a major part of the budget will be used for traineeship support. These efforts will position UC to compete more effectively for upcoming federal funds to study ocean acidification, and train the next generation of scientists who will contribute to knowledge on ocean acidification and impacts on the California coast. The activities of this proposal will fulfill three goals that are central to the UC MRU program. (1) The studies described here will directly address the impacts of climate change on coastal marine ecosystems, a critical issue for California, (2) this proposal strategically prepares a research team within UC that can compete for external research funds for the study of ocean acidification, and (3) support for this group will build a multidisciplinary team that takes advantage of complementary expertise among graduate students and postdoctoral fellows in the UC system. Ultimately, this program will serve as an outstanding recruitment tool to attract high quality graduate students to the UC campuses.
Peramphithoe Conlan & Bousfield 1982
Creators: name: Souza-Filho, Jesser F.
name: Guedes-Silva, Elkênita
name: Senna, André R.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Ampithoidae
Peramphithoe

description: Genus Peramphithoe Conlan & Bousfield, 1982
Peramphithoe Conlan & Bousfield 1982: 60; Poore & Lowry 1997: 927; LeCroy 2002: 255; Kim et al. 2012: 4.
Type species. Ampithoe femorata Krøyer, 1845, original designation.
Diagnosis. See Conlan & Bousfield (1982); Poore & Lowry (1997); Kim et al. (2012), Shin et al. (2015).
Species composition. Peramphithoe africana Milne & Griffiths, 2013; P. annenkovae (Gurjanova, 1938); P. aorangi (J.L. Barnard, 1972); P. baegryeongensis Kim & Kim, 1988; P. bungareei Hughes & Peart, 2013; P. chujaensis Kim, Hong, Conlan & Lee, 2012; P. conlanae sp. nov.; P. e o a (Brüggen, 1907); P. falsa (K.H. Barnard, 1932); P. femorata (Krøyer, 1845); P. guryongensis Shin, Coleman, Hong & Kim, 2015; P. humeralis (Stimpson, 1864); P. lessoniophila Conlan & Bousfield, 1982; P. lindbergi (Gurjanova, 1938); P. mea (Gurjanova, 1938); P. namhaensis Kim & Kim, 1988; P. orientalis (Dana, 1853); P. parmerong Poore & Lowry, 1997; P. p l e a (J.L. Barnard, 1965); P. spuria (Krapp-Schickel, 1978); P. stypotrupetes Conlan & Chess, 1992; and P. t e a (J.L. Barnard, 1965).
description: Published as part of Souza-Filho, Jesser F., Guedes-Silva, Elkênita & Senna, André R., 2016, New record of the genus Peramphithoe Conlan & Bousfield, 1982 (Amphipoda: Ampithoidae) from Brazilian coast, with description of a new species, pp. 188-194 in Zootaxa 4136 (1) on page 189, DOI: 10.11646/zootaxa.4136.1.11, http://zenodo.org/record/268251
title: Chaotic vibrations of the vibro-impact mechanism in a hand-held electro-pneumatic drill
Creators: name: Ferdek, Urszula
Publisher: name: Poznań University of Technology
publisherIdentifier: https://ror.org/00p7p3302
publisherIdentifierScheme: ROR
Year: 2024

description: Vibrations in Physical Systems, 35(3), 2024312-1 - 2024312-13
title: SUPPLEMENTAL MATERIAL for Pax proteins mediate segment-specific functions in proximal tubule survival and response to ischemic injury
Creators: name: Beamish, Jeffrey
Publisher: name: University of Michigan
Year: 2024
Subjects: subject: Internal Medicine
subject: Health Sciences

description: Supplemental Material for associated manuscripte
description: Acute kidney injury (AKI) is a common clinical syndrome with few effective treatments. Though the kidney can regenerate after injury, the molecular mechanisms regulating this process remain poorly understood. Pax2 and Pax8 are DNA-binding transcription factors that are upregulated after kidney injury. However, their function during the response to AKI remains incompletely defined. In this report, we develop a model of ischemic AKI in female mice with mosaic nephrons comprised of both Pax2 and Pax8 mutant and wildtype proximal tubule cells with fixed lineages. Each population therefore experiences identical physiological and injury conditions in the same animal. (R1.m.1) In these female mice, we show that before injury the S1 and S2 segments of the proximal tubule are depleted of Pax-mutant cells while mutant cells are preserved in the S3 segment. Retained S3 Pax-mutant cells develop a preconditioned phenotype that overlaps with gene expression signatures in AKI. In response to ischemic AKI, which most strongly damages the S3 proximal tubule, injury-resistant mutant S3 cells are more likely to proliferate. Pax-mutant cells then preferentially repopulate the S3 segment of the proximal tubule. Our results indicate that Pax2 and Pax8 are not required for regeneration of the S3 proximal tubule after ischemic AKI. Together, our findings indicate that Pax proteins play a critical role determining the segment-specific proximal tubule gene expression patterns that dictate vulnerability to ischemic injury.
UC/ACCORD Renewal Application
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: This is a renewal application for UC/ACCORD. UC/ACCORD is asking for a five-year renewal, at $400,000 per year, to continue to conduct and disseminate research that is directly relevant to increasing the equity along the education pipeline from pre-school to graduate school. UC/ACCORD’s theme, “research to make a difference,” encapsulates its primary mission. To accomplish that mission UC/ACCORD has three goals: 1) to conduct and disseminate research that is directly relevant to increasing the equity along the education pipeline from pre-school to graduate school; 2) to take that body of research and apply it to educational practice and policy across the State of California; 3) to identify, support, and prepare the next generation of University of California scholars engaged in research on issues of educational equity, opportunity, and access. We are asking for funding to continue our work in the following three areas: 1) awarding Dissertation and Postdoctoral Fellowships and Faculty Seed Grants to UC graduate students and faculty, (2) convening the Annual Conference of UC/ACCORD Fellows, and (3) publishing the annual California Educational Opportunity Reports and working with the California educational policy community. Over the last eight years of existence, UC/ACCORD has competitively awarded 58 dissertation fellowships, 11 postdoctoral fellowships, and 26 faculty seed grants, convened seven Annual Conferences of ACCORD Fellows, and produced numerous policy briefs, reports, and monographs related to our research on educational equity, opportunity, and access. In each of these three areas we have demonstrated that they strengthen the capacity of the UC to support graduate students and junior faculty as they make their way to and through careers in the academy. UC/ACCORD projects increase the UC competitiveness with other public and private institutions of higher education because of the quality and applicability of research we produce through our fellowships, grants, and policy initiative programs. In our eight years of existence, UC/ACCORD has also benefitted the UC system in its efforts to support its land grant mission—creating greater educational equity, opportunity, and access for all of California’s students.
Eupyrgota Coquillett 1898
Creators: name: El-Hawagry, Magdi S.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Pyrgotidae
Eupyrgota

description: Subgenus EUPYRGOTA —Nominotypical subgenus
See: Korneyev (2014).
Eupyrgota latipennis (Walker, 1849)
Oxycephala latipennis Walker, 1849: 1087. Holotype. Sierra Leone (BMNH). Adapsilia ypsilon Hendel, 1914a: 89. Holotype. Sierra Leone (BMNH). Distribution. AF: Congo, Egypt [Gebel Elba], Nigeria, Rwanda, Saudi Arabia [Al-Baha], Sierra Leone, Uganda. Egyptian localities. Gebel Elba:?.
Biology. Members of the family Pyrgotidae are, as far as known, parasitoids of adult scarab beetles. Source: Korneyev (2014).
Dates of collection. January.
description: Published as part of El-Hawagry, Magdi S., 2017, Catalogue of Egyptian Tephritoidea (Diptera: Schizophora: Acalyptratae), pp. 151-190 in Zootaxa 4299 (2) on page 159, DOI: 10.11646/zootaxa.4299.2.1, http://zenodo.org/record/843233
Carbon nanotube composite scaffolds for differentiation of human neural stem cells
Creators: name: Heden, Gregory
Publisher: name: No Publisher Supplied
Year: 2013

description: Carbon nanotubes have been utilized in a variety of fields due to their unique and extraordinary properties. Here, a process to incorporate single-walled carbon nanotubes (SWNTs) into electrospun polymer mats is investigated in order to create novel composite scaffolds to enhance the differentiation of human neural stem cells (hNSCs) into fully developed neurons. An electrowetting method is first explored using a potential difference as a driving force. Although successful wetting was achieved, a vacuum impregnation method was used to further improve the uniformity of the SWNT distribution in the scaffold. This process produced homogenously wetted scaffolds that are electrically conductive, mechanically robust, and highly biocompatible with hNSC cultures in vitro. These scaffolds showed an increased expression of two major neuronal markers, Neurofilament M (NFM) and microtubule-associated protein-2 (MAP2) compared to plain electrospun polymer scaffolds. During differentiation tests, an additional electrical stimulation was applied and showed even further enhancement. This is the first demonstration of electrical stimulation enhancing neuronal differentiation of human neural stem cells on CNT-based composite scaffolds.
Nitrate health risk and geochemical characteristics of water in a semi-urban: implications from graphical plots and statistical computing
Creators: name: Egbueri, J. C.
name: Agbasi, J. C.
name: Ikwuka, C. F.
name: Chiaghanam, O. I.
name: Khan, M. I.
name: Khan, M. Y. A.
name: Khan, N.
name: Uwajingba, H. C.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The aim of this study was to assess the nitrate health risks due to water consumption via oral and dermal contact routes and to evaluate the geochemical characteristics of waters in the Umunya area, Nigeria, as implied from ionic ratios, graphical plots, and multivariate statistics. This study is the first to assess the human health risks associated with nitrate contamination in the semi-urban. Standard methods were used to achieve the aim of the study. Water from commercial and household sources were sampled. Measured physicochemical properties showed that the water resources are slightly contaminated. Health hazard quotient (oral) ranged from 0–0.5072 for men, 0–0.5994 for women, and 0–0.6858 for children. On the other hand, the maximum hazard quotient (dermal) for men, women, and children were 0.0013, 0.0016, and 0.0042, respectively. The total hazard index for men, women, and children respectively varied from 0–0.509, 0–0.601 and 0–0.690. Overall, it was indicated that 46.67%, 53.33%, and 53.33% of the water samples expose men, women, and children to low chronic health risk of nitrate. However, the risk for water ingestion was higher than that for dermal absorption. Hydrogeochemical plots revealed that Ca2+-Mg2+-HCO3− and Na+-HCO3− water types, representing recharge and base ion exchange processes, respectively, are predominant. Principal component analysis and R-type hierarchical clustering revealed that the hydrogeochemical characteristics are mostly controlled by geogenic factors than human-related factors. The geology of the area and silicate weathering processes were implicated as the major influencers of the hydrogeochemistry. For sustainable development and improved water monitoring in the area, the insights provided in this paper are considered very beneficial.
Italian Studies Interdisciplinary Multicampus Research Group
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: At the University of California, faculty working in Italian Studies are for the most part widely dispersed across the disciplines of the human sciences. At the present time there are at least seventy (70) distinguished faculty in the UC system who work in Italian Studies, often with numerous graduate students, although they may find themselves based in departments of Geography, Sociology, History, Art History, Religious Studies, Literature, or Film Studies (to name only some). The purpose of the MRPI in Italian Studies is to establish a transversal and interdisciplinary research group whose undertakings will draw on the extraordinary talents and accomplishments of these faculty and students in a way that will have a beneficial impact not only on the University of California but on the field as a whole. Increasingly reconceived as a locus of intersection, hybridization and recirculation, Italy now appears to many scholars of Europe and the Mediterranean basin to offer an invaluable model of fluid cultural and social exchange that cannot be measured by finding the ideas and products that the West took from the East, or vice versa, but rather is defined by the deliberate and creative assimilation of diverse traditions across borders, resulting in periods of powerful cultural and social dynamism (such as the Renaissance or Futurism), as well as in influential political models ranging from the medieval city-state to Fascism. The principal proposed activities of the Italian Studies MRPI, involving 6 UC campuses, fall under the rubric of collaborative “digital humanities” or “digital human sciences.” These include two high-visibility projects that aim to encourage outstanding interdisciplinary research, publication and teaching in the field of Italian Studies while supporting innovative graduate student research and publication. The first of these is the production and publication of the new scholarly peer-review electronic journal CALIFORNIA ITALIAN STUDIES, whose first issue is to appear shortly with the California Digital Library, but whose forthcoming issues are already in preparation; and the second is the ongoing development of a web portal for digital Italian Studies research and pedagogy, which organizes, describes and links (often little-known) electronic resources in the field across a wide range of disciplines. The site is currently found at www.ihc.ucsb.edu/italianstudies. Around these two digital projects the MRPI will build its network of faculty and graduate student researchers, connecting them into a unit seeking to effect new critical mappings and remappings of the field. CIS and its associated activities will encourage faculty and graduate student production and peer-review publication of path-breaking research, made available around the world in conjunction with the name “University of California.”
Branched chain amino acid supplementation modulates the effect of inflammatory mediators on the function of a hepatoma cell line
Creators: name: Hashemi, Sharareh
Publisher: name: No Publisher Supplied
Year: 2013

description: Severe trauma injuries often lead to a prolonged inflammatory response associated with metabolic abnormalities. These abnormalities lead to persistent skeletal muscle proteolysis and rapid loss of lean body mass, which may lead to multiple organ dysfunction and death. The liver plays an important role in this systemic response to injury by modulating the inflammatory processes, immune functions, and metabolic pathways. The acute phase of the response is characterized by the release of inflammatory mediators, including proinflammatory cytokines and reactive oxygen species (ROS), as well as a change in the protein secretion pattern and increased amino acid utilization by the liver. When these changes persist for long periods of time, they likely contribute to the body’s negative nitrogen balance as well as loss of lean body mass (LBM). Among all proteins secreted by the liver, albumin is the most abundant one and its secretion rate significantly decreases in inflammatory states, and results in a lower circulating concentration in patients. Albumin provides the critical colloid osmotic pressure to regulate the passage of water and diffusible solutes through the capillaries. Increased utilization of amino acids in trauma is thought to be important for defense against diseases; however, it reduces body stores of proteins and free amino acids to supply amino acid needs for tissue repair, acute phase protein production, and gluconeogenesis. Nutritional supplementation is currently being used to alleviate endogenous nitrogen depletion and to maximize protein synthesis for optimal wound healing and immune function. Among nutritional supplements, there has been increased interest in using branched chain amino acids (BCAAs), and clinical studies suggest that BCAAs can enhance liver function in inflammatory states. The mechanism whereby BCAAs impact the liver function during inflammation is unclear. The purpose of this research is to investigate the effect of proinflammatory mediators (more specifically the cytokines interleukin-1ß & interleukin-6) and reactive oxygen species H₂O₂, and BCAAs on a cell culture model of liver consisting of HepG2/C3A hepatoma cells. It was found that these mediators reversibly suppressed albumin and urea production in a dose-dependent manner, and also decreased the amount of the intracellular antioxidant reduced glutathione. BCAA supplementation mitigated the effect of these inflammatory mediators; however, this effect was maximized at a relatively low concentration of BCAAs, above which no further benefit was observed. Therefore, BCAAs are potentially beneficial to support liver function during inflammation.
Assessment of As, Cr, Cd, and Pb in urban surface water from a subtropical river: contamination, sources, and human health risk
Creators: name: Kubra, Khadijatul
name: Mondol, Anwar Hossain
name: Ali, Mir Mohammad
name: Islam, Md. Saiful
name: Akhtar, Shahrina
name: Ahmed, A. S. Shafiuddin
name: Bhuyan, Md. Simul
name: Rahman, Md. Mezbaur
name: Abu Bakar Siddique, Md.
name: Islam, Abu Reza Md. Towfiqul
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: This work aimed to determine the level of some toxic elements (As, Cr, Cd, and Pb) in the water of the Rupsha River, Bangladesh, concerning their potential dangers to human exposure. The elemental concentrations (mg/L) were determined using Atomic Absorption Spectrometer and found to decrease in the order of Cr (0.041) > Pb (0.029) > As (0.004) > Cd (0.002). The level of elements in this river water surpasses various international limits, making it unfit for human consumption. Furthermore, the metal pollution index and contamination index indicated that the water was also unsuitable for this purpose. The elements chosen were persuasive to discern the hazard quotient of non-carcinogenic risk. Moreover, total targeted hazard quotient (TTHQ) values were found for adults and children within acceptable limits (TTHQ <1). The value of carcinogenic risk did not surpass the range (10−6 to 10−4) of the threshold limit. Due to their high-water consumption per unit of body-weight and physiological development, children were found to be more sensitive than adults. Multivariate analyses demonstrated that human activities were the primary origin of toxic elements in river water. According to the findings, urban and industrial effluents should be treated before being released into rivers. Development along the river bank must be carefully controlled to safeguard the river environment. In the end, this will improve the quality of the water and lower the chance that people will be exposed to metals.
Stress, socioeconomic status, and obesity
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: This application brings together a strong interdisciplinary team of scientists from health psychology, nutritional sciences, endocrinology, and epidemiology to address the obesity epidemic, with a focus on the role of social disadvantage and stress on obesity, and for the development of effective interventions that are relevant to public policy. The new MCRP will conduct translational studies, provide graduate students research experiences with multiple campus mentors; develop obesity related graduate curriculum; develop experimental assays to identify biological mechanisms that influence metabolism and weight retention; and hold multicampus seminars and an annual symposium. We aim to test novel interventions targeting the biological pathways by which stress and reward/pleasure from palatable food influence eating behaviors and abdominal fat deposition. Our translational approach encompasses the psychology of eating and behavior change, and the neuroscience of stress, appetite and reward, to test whether modulating the neural reward pathways and stress response systems reduces abdominal obesity and weight. We will seek extramural funding to conduct observational and interventional studies, especially among vulnerable populations, and perform policy analyses related to factors influencing stress and eating behaviors. We will build upon the strong foundation in teaching, mentoring and research at the UC San Francisco’s Center for Obesity, Assessment and Treatment Center (stress pathways), UC Berkeley’s Center for Weight and Health (evaluation and policy), and UC Davis Department of Nutrition (nutrition and biological pathways). Funding from this mechanism will further strengthen current collaborations between UCSF, UCB, and UCD researchers, on ongoing projects as well as to join efforts to revive and extend the NHLBI-funded National Health and Growth Study (NGHS) that investigated racial disparities in growth and development of white and black girls from 1988 to 1998. This cohort now provides an opportunity to examine how obesity is transmitted to the next generation, since these girls are now adults. These activities will set the stage for an independently funded cross-campus center. There is currently no west coast obesity research center, and the focus on stress/reward pathways to obesity, a cutting edge new area, is underrepresented at University of California schools. Funding for a new MCRP will expand and synergize the scope of this novel and timely research focus at each campus, increase training activities, and lay the ground-work for an NIH Center grant. Specifically, the new MCRP will be well poised to compete for the NIDDK P30 “Obesity Nutrition Research Center” grants that will reopen in 2012.
University of California Center for Energy and Environmental Economics (UCE3)
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: University of California Energy and Environmental Initiative Severin Borenstein, PI Abstract: It is impossible to address today’s policy challenges in either energy or the environment without a deep understanding of both areas. The proposed University of California Energy and Environmental Initiative (UCEEI) will combine two world-class research centers in energy and environmental economics and policy. Such an initiative would be unique amongst academic institutions and would give the UC system a major competitive advantage in attracting scholars and graduate students interested in these fields. UCEEI will function as a hub of energy and environmental economic research excellence, drawing renowned researchers as visiting scholars from the UC campuses and other top-tier research universities throughout the world. UCEEI will have a physical presence at both the UC Energy Institute inside the Haas School of Business at UC Berkeley and at the Bren School of Environmental Science & Management at UC Santa Barbara. UCEEI will focus on four general research areas: Energy and Climate Policy, Energy Efficiency, Market-Based Environmental Regulations, and Behavioral Economics and the Environment. The initiative will provide resources to bring affiliated faculty and graduate students from sister UC campuses to the two UCEEI locations for both short-term events and longer-term visits. UCEEI will host intensive collaborative research events, such as workshops and conferences and offer a working-paper series for affiliated research. In addition, UCEEI will implement innovative collaborative educational initiatives. First, graduate students at the primary campuses and sister campuses will receive support to spend time at the other locations. Second, UCEEI will develop an innovative cross-disciplinary curriculum to enhance the existing environmental programs at Bren and the energy programs at the Haas School. In both cases, students specializing in one field will gain access to faculty in the other. Because UCEEI will leverage the existing infrastructure of UCEI, the new initiative will be ready to operate as of July 1, 2009. We will request UCOP support for a five-year transitional period. This unique energy and environment research center will be well positioned to receive extramural funds in a time when solving the U.S.’s energy issues is a priority.
Habitar y morir en el cercado grande de los santuarios : detección de áreas de actividad entre la ocupación Herrera-Muisca a partir de una prospección geofísica
Creators: name: González Herrera, Carla Milena
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Arqueología - Colombia
subject: Comunidades indígenas - Aspectos sociales
subject: Monumentos - Cuidado y tratamiento
subject: Cercado grande de los santuarios
subject: Sensores remotos
subject: Áreas de actividad residenciales
subject: Áreas de actividad mortuorias
subject: Entierro residencial

description: El presente estudio se centra en la detección de áreas de actividad residenciales y mortuorias en la reserva arqueológica de El Cercado Grande de los Santuarios, durante la ocupación Herrera-Muisca, ubicada dentro de las instalaciones de la Universidad pedagógica y tecnológica de Tunja -UPTC-. La investigación se llevó a cabo utilizando tecnologías geofísicas, como el Perfilador EMP-400, para realizar una prospección arqueológica no intrusiva. Esto contribuye al conocimiento sin necesidad de excavaciones convencionales, cumpliendo con los lineamientos establecidos en el Plan de Manejo Arqueológico de la zona. El objetivo de este estudio es explorar las dinámicas socioculturales, haciendo uso de la noción de “entierro residencial”. Esta perspectiva permite analizar dos líneas de evidencia, que, en el caso particular del área de estudio, han sido investigadas de manera independiente: los aspectos domésticos y los funerarios. Utilizando el análisis antropológico de hogar, esta dinámica revela la influencia activa de las prácticas mortuorias en la vida diaria de las comunidades, así como las interacciones cotidianas que pudieron haber existido entre los vivos y los muertos en un mismo paisaje.
description: The present study focuses on the detection of residential and mortuary activity areas in the archaeological reserve of El Cercado Grande de los Santuarios, during the Herrera-Muisca occupation, located within the facilities of the Pedagogical and Technological University of Tunja -UPTC- . The investigation was carried out using geophysical technologies, such as the EMP-400 Profiler, to carry out a non-intrusive archaeological survey. This contributes to knowledge without the need for conventional excavations, complying with the guidelines established in the Archaeological Management Plan of the area. The objective of this study is to explore sociocultural dynamics, making use of the notion of “residential burial.” This perspective allows us to analyze two lines of evidence, which, in the particular case of the study area, have been investigated independently: the domestic and funerary aspects. Using anthropological analysis of the home, this dynamic reveals the active influence of mortuary practices on the daily life of communities, as well as the daily interactions that may have existed between the living and the dead in the same landscape.
Ceratitis MacLeay
Creators: name: El-Hawagry, Magdi S.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Tephritidae
Ceratitis

description: Genus CERATITIS MacLeay
Ceratitis MacLeay, 1829: 482. Type species: Ceratitis citriperda Macleay, 1829 (= Tephritis capitata Wiedemann, 1824), monotypy.
Petalophora Macquart, 1835b: 454. Type species: Tephritis capitata Wiedemann, 1824, monotypy.
Pinacochaeta Munro, 1933: 34 (proposed as a subgenus). Type species: Ceratitis pinax Munro, 1933, original designation.
Halterophora Rondani, 1861: 10. Unjustified new (replacement) name for Ceratitis MacLeay (Preoccupied by Endlicher 1836); replaced name misspelled as Ceratites.
Ceratites Agassiz, 1846: 7. Misspelling of Ceratitis MacLeay.
description: Published as part of El-Hawagry, Magdi S., 2017, Catalogue of Egyptian Tephritoidea (Diptera: Schizophora: Acalyptratae), pp. 151-190 in Zootaxa 4299 (2) on page 159, DOI: 10.11646/zootaxa.4299.2.1, http://zenodo.org/record/843233
El yacimiento prehispánico sueños de libertad del Municipio de Arjona : una aproximación al modo de vida a través de la producción lítica
Creators: name: Chanagá Ávila, Miguel Ángel
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Comunidades rurales - Aspectos sociales
subject: Arqueología - Colombia
subject: Desarrollo de la comunidad
subject: Lítica
subject: Formativo
subject: Caribe colombiano
subject: Modos de vida
subject: Producción
subject: Yacimiento arqueológico

description: La materialidad lítica es importante en la arqueología, porque nos permite observar comportamientos en torno a la producción, movilidad, modos de vida y usos aplicados hacia la lítica. Los habitantes de Arjona del periodo del formativo basaron la producción lítica desde una tecnología expedita, permitiéndoles tener acceso a fuentes de materias primas locales de las formaciones geológicas de San Jacinto y San Cayetano. Un conjunto de artefactos líticos recuperados de dos cortes del Yacimiento Sueños de Libertad, permitirán a través de una reconstrucción de una cadena operatoria, observar los modos de vida desarrollados por los habitantes de Arjona, dentro del periodo del Formativo, todo por medio de la clasificación y categorización.
description: Lithic materiality is important in archaeology, because it allows us to observe behaviors around production, mobility, ways of life and uses applied to lithics. The inhabitants of Arjona in the Formative period, based lithic production on an expeditious technology, allowing them to have access to sources of local raw materials from the geological formations of San Jacinto and San Cayetano. A set of lithic artifacts recovered from two sections of the Arjona site, will allow, through a reconstruction of an operational chain, to observe the ways of life developed by the inhabitants of Arjona, within the Formative period, all through classification and categorization.
Sustainable Transport: Technology, Mobility, Infrastructure
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The University of California Institute of Transportation Studies (ITS), a Multicampus Research Unit with primary branches at Berkeley, Davis, and Irvine and affiliated centers at Los Angeles, Riverside, and Santa Barbara, proposes a new initiative to target the environmental and energy sustainability of California’s transport system. Our primary goal is to generate knowledge, methods, and policies to advance the transformation of transportation and energy systems—achieving socially beneficial changes in technologies, institutions, behavior, and policy, introducing new technologies and practices, and supporting the adoption of effective policies. Our program will be driven by specified outcomes, including new methods, policy instruments, and knowledge that feed directly into government and industry initiatives. Designing effective strategies and policies is critical, not just for the benefit of California but also because California is seen as a world model in addressing these challenges. We will assemble cross-campus research teams to pursue integrated solutions for 1) fuels and vehicles, 2) infrastructure investment and system management; and 3) land use and mobility planning. Each of these sub-systems must be transformed to achieve large reductions in oil use and greenhouse gas emissions. Key fuel and vehicle solutions include biofuels, electricity and hydrogen, consumed in a variety of electric-drive vehicle technologies. Infrastructure investment and system management solutions will target innovations such as high speed rail, bus rapid transit, and information technology based services. Land use and mobility solutions will feature reduced sprawl, increased transit ridership and new transport services. We will leverage existing but fragmented capabilities of our member campuses across the physical, environmental, and social sciences. We request $1.55M per year for five years. This new funding will allow ITS to initiate visionary projects and to create new capabilities in anticipation of industry, government, and societal needs. This funding will leverage activities across six campuses, positioning us for large center proposals to companies, governments, and foundations, as well as greatly expanded core funding from the State (via their Public Transportation Account). With MRPI funding, we will launch the premier center of sustainable transportation in the world. This ITS center on sustainable transportation, administered by ITS-Irvine, will be managed by the directors of the three principal ITS campuses, with senior faculty from the other three campuses serving on the executive committee. An advisory board comprising senior leaders and experts from government, industry, and academia has been formed to evaluate projects and provide input to our plans.
Judging failures in moral development
Creators: name: Harcourt, Heather F.
Publisher: name: No Publisher Supplied
Year: 2013

description: This study examines the influence of moral development and course of antisocial behavior on mental disorder judgments of social work clinicians and social work students presented with clinically realistic vignettes meeting criteria for conduct disorder according to the fourth edition, text revision, of the Diagnostic and Statistical Manual of Mental Disorders (DSM–IV–TR; American Psychiatric Association, 2000).  Clinical vignettes were designed to examine whether low moral development and life-course persistent antisocial behavior were interpreted as internal dysfunction, which is required by DSM–IV–TR to make a judgment of mental disorder.  In a 3x3 design, vignettes were manipulated to include information about moral development and course of antisocial behavior as evidence of internal dysfunction, compared to a neutral condition.  Vignette packets were mailed to experienced social workers and distributed to students in first-year MSW classes.  Respondents (N= 241) answered the question “this youth has a mental disorder” for 3different vignettes.   Vignettes were separated into three independent samples for logistic regression analyses, in which neutral vignettes were used as reference categories.  Low moral development did not affect mental disorder judgments. The presence of life-course persistent antisocial behavior significantly increased the odds of a mental disorder judgment across three samples (OR=5.351, p