cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 4: of Maternal variant in the upstream of FOXP3 gene on the X chromosome is associated with recurrent infertility in Japanese Black cattle
Creators: name: Arishima, Taichi
name: Sasaki, Shinji
name: Isobe, Tomohiro
name: Ikebata, Yoshihisa
name: Shimbara, Shinichi
name: Ikeda, Shogo
name: Kawashima, Keisuke
name: Suzuki, Yutaka
name: Watanabe, Manabu
name: Sugano, Sumio
name: Mizoshita, Kazunori
name: Sugimoto, Yoshikazu
Publisher: name: figshare
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Transcriptional binding sites of neighboring g.92,377,635A > G in the upstream region of FOXP3. (a) Transcriptional binding site analysis of neighboring g.92,377,635A > G was analyzed by JASPAR. Position Frequency Matrix (PFM) was converted to Position Specific Scoring Matrices (PSSM). PSSM scoring scales are represented by superscripted letters as follows: a score; sum of values from indicated cells of the matrix, b relative scores; normalization of the scores to the range of 0–1. (b) SeqLogo; a graphical representation of frequency matrix. Y-axis is information content, which reflects the strength of the pattern in each column of the matrix. A magenta arrow indicates g.92,377,635A > G. (PDF 518 kb)
H2CO distribution and formation in the TW Hya disk
Creators: name: Oberg, Karin I.
name: Guzman, Viviana V.
name: Merchantz, Christopher J.
name: Qi, Chunhua
name: Andrews, Sean M.
name: Cleeves, L. Ilsedore
name: Huang, Jane
name: Loomis, Ryan A.
name: Wilner, David J.
name: Brinch, Christian
name: Hogerheijde, Michiel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: H2CO is one of the most readily detected organic molecules in protoplanetary disks. Yet its distribution and dominant formation pathway(s) remain largely unconstrained. To address these issues, we present ALMA observations of two H2CO lines (3_{12}-2_{11} and 5_{15}-4_{14}) at 0".5 (~30 au) spatial resolution toward the disk around the nearby T Tauri star TW Hya. Emission from both lines is spatially resolved, showing a central depression, a peak at 0".4 radius, and a radial decline at larger radii with a bump at ~1", near the millimeter continuum edge. We adopt a physical model for the disk and use toy models to explore the radial and vertical H2CO abundance structure. We find that the observed emission implies the presence of at least two distinct H2CO gas reservoirs: (1) a warm and unresolved inner component (<10 au), and (2) an outer component that extends from ~15 au to beyond the millimeter continuum edge. The outer component is further constrained by the line ratio to arise in a more elevated disk layer at larger radii. The inferred H2CO abundance structure agrees well with disk chemistry models, which predict efficient H2CO gas-phase formation close to the star, and cold H2CO grain surface formation, through H additions to condensed CO, followed by non-thermal desorption in the outer disk. The implied presence of active grain surface chemistry in the TW Hya disk is consistent with the recent detection of CH3OH emission, and suggests that more complex organic molecules are formed in disks, as well.
description: Accepted for publication in ApJ
Additional file 2: of Identifying lower limb specific and generalised joint hypermobility in adults: validation of the Lower Limb Assessment Score
Creators: name: Meyer, Kaitlin
name: Cliffton Chan
name: Hopper, Luke
name: Nicholson, Leslie
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: The Beighton Score. This file contains the standardised criteria of the five tests involved in scoring of the Beighton in this study. (DOCX 19 kb)
The emerging storywriter: a study of linguistic and meta-linguistic phenomena in the writing of Cèmuhi, a Melanesian language of New Caledonia
Creators: name: Lecompte, Maarten
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This PhD thesis is an analysis of the representation of the Kanak voice in the practice and product of writing in Cèmuhi, an Austronesian language of New Caledonia. It investigates how Cèmuhi language and culture have been represented in a variety of works and texts that were produced in Cèmuhi as a result of practices that are ideologically motivated. In order to do so, I adopt both a diachronic and a synchronic approach. I first give a critical historical overview of the various interest groups that were involved in the codification of the Cèmuhi language, which can be traced along three subsequent stages or movements of writing: the first stage begins in the middle of the 19th century, when the Marist priests started to translate religious works into the Cèmuhi language. They were followed by visits of French ethnographers (e.g. Alban Bensa and André Haudricourt) and linguists (e.g. Jean-Claude Rivierre) who developed grammars, dictionaries, and ethnographies, based on the practice of transcribing oral stories. The third stage is that of Cèmuhi texts written by an emerging indigenous writer, Suzanne Poinine, who is one of the few Cèmuhi speakers and, in fact, Kanak in general, who has used the medium of writing in her mother tongue. An analysis of her writing practice and the different text genres and textual artefacts that she has produced over more than 40 years form the centre-piece of this thesis and are subjected to a social and historical analysis of both linguistic and meta-linguistic phenomena.
A Note on One Less Known Class of Generated Residual Implications
Creators: name: Havlena, Vojtěch
name: Hliněná, Dana
Publisher: name: arXiv
Year: 2016
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics

description: This paper builds on our contribution [Havlena and Hlinena, 2016] which studied modelling of the conjunction in human language. We have discussed three different ways of constructing conjunction. We have dealt with generated t-norms, generated means and Choquet integral. In this paper we construct the residual operators based on the above conjunctions. The only operator based on a t-norm is an implication. We show that this implication belongs to the class of generated implications I^g_N which was introduced in [Smutna, 1999] and studied in [Biba and Hlinena, 2012]. We study its properties. More, we investigate this class of generated implications. Some important properties, including relations between some classes of implications, are given.
description: In Proceedings MEMICS 2016, arXiv:1612.04037
title: Are female skins sold for a lower price? Evidence from the Fortnite game
Creators: name: Stadtmann, Georg
name: Tosun, Aynur Dilan
name: Pierdzioch, Christian
Publisher: name: Europa-Universität Viadrina Frankfurt
Year: 2020

description: Much significant research has been done to shed light on discrimination of females in, for example, labor markets. Less is known, in contrast, about the amount of discrimination in the virtual world of online gaming. In an early study, Castronova (2004) finds that female avatars receive about 10\% lower prices in online auctions. In this research note, we re-examine the pricing of avatars sold in the Fortnite game. We cannot reject the null hypothesis that female and male avatars are sold at the same prices. We also account for the impact of a Fortnite sex scandal on the price differential between female and male avatars.
description: Discussion papers of the Faculty of Business Administration and Economics, 420
Characterizing DAG-depth of Directed Graphs
Creators: name: Bezek, Matúš
Publisher: name: arXiv
Year: 2016
Subjects: subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences

description: We study DAG-depth, a structural depth measure of directed graphs, which naturally extends the tree-depth of ordinary graphs. We define a DAG-depth decomposition as a strategy for the cop player in the lift-free version of the cops-and-robber game on directed graphs and prove its correctness. The DAG-depth decomposition is related to DAG-depth in a similar way as an elimination tree is related to the tree-depth. We study the size aspect of DAG-depth decomposition and provide a definition of mergeable and optimally mergeable vertices in order to make the decomposition smaller and acceptable for the cop player as a strategy. We also provide a way to find the closure of a DAG-depth decomposition, which is the largest digraph for which the given decomposition represents a winning strategy for the cop player.
description: In Proceedings MEMICS 2016, arXiv:1612.04037
Data-pattern tomography of entangled states
Creators: name: Reut, Vadim
name: Mikhalychev, Alexander
name: Mogilevtsev, Dmitri
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We discuss the data-pattern tomography for reconstruction of entangled states of light. We show that for a moderate number of probe coherent states it is possible to achieve high accuracy of representation not only for single-mode states but also for two-mode entangled states. We analyze the stability of these representations to the noise and demonstrate the conservation of the purity and entanglement. Simulating the probe and signal measurements, we show that systematic error inherent for representation of realistic signal response with finite sets of responses from probe states still allows one to infer reliably the signal states preserving entanglement.
description: 9 pages, 10 figures
Confinement of Half-quantized Vortices in Coherently Coupled Bose-Einstein Condensates: Simulating Quark Confinement in QCD
Creators: name: Eto, Minoru
name: Nitta, Muneto
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We demonstrate that the confinement of half-quantized vortices (HQVs) in coherently coupled Bose-Einstein condensates (BECs) simulates certain aspects of the confinement in $SU(2)$ quantum chromodynamics (QCD) in 2+1 space-time dimensions. By identifying the circulation of superfluid velocity as the baryon number and the relative phase between two components as a dual gluon, we identify HQVs in a single component as electrically charged particles with a half baryon number. Further, we show that only singlet states of the relative phase of two components can stably exist as bound states of vortices, that is, a pair of vortices in each component (a baryon) and a pair of a vortex and an antivortex in the same component (a meson). We then study the dynamics of a baryon and meson; baryon is static at the equilibrium and rotates once it deviates from the equilibrium, while a meson moves with constant velocity. For both baryon and meson we verify a linear confinement and determine that they are broken, thus creating other baryons or mesons in the middle when two constituent vortices are separated by more than some critical distance, resembling QCD.
description: 9 pages, 9 figures
Exploring teachers’ perceptions and implementation of task-based language teaching in the Australian ELICOS sector
Creators: name: Ly, Truc Thi Thanh
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Task-based language teaching (TBLT), which is an approach evolving from communicative approach, has been considered one of the most popular trends in teaching English as a foreign or second language. This research applies a mixed-methods approach to explore teachers‘ perceptions of task-based language pedagogy and its implementation in the ELICOS (English Language Intensive Courses for Oversea Students) setting. The sources of data were gathered in two phases, comprising an online survey with 58 respondents from various ELICOS colleges across Australia, and semi-structured interviews with eight teachers who have varying teaching experience. Based on the data which were both quantitatively and qualitatively analyzed, the overall findings show that the majority of the teachers have a high level of understanding of TBLT principles and hold positive attitudes towards its execution in their classroom practice. The research also reveals a number of constrains that affect the successful implementation of TBLT, which thus proposes useful implications for facilitating the efficiency of TBLT adoption in the Australian ELICOS sector.
Non-monolithic analysis of Islam and terrorism in Australian press (1990-2015)
Creators: name: Pavlovic, Mirko
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Since 9/11, the mass media space in Western countries, including Australia, is heavily populated with news on terrorism that is linked to the Middle East, Islam, and Muslims. While research on Western media reporting on Islam and terrorism—providing negative representations of Islam—is not uncommon, studies examined in the process are qualitative in nature, relying on interviews and select newspaper content; and inadvertently their findings support Edward Said’s Orientalism theory. Mindful of Orientalism, this study sets out to establish whether there is quantitative evidence supporting the qualitative studies on reporting on Islam and terrorism.This thesis undertakes post-positivist quantitative content analysis of newspaper articles published in Australian newspapers from 1990 to 2015, using the largest national daily (The Australian), the largest daily metropolitan/state broadsheet (The Sydney Morning Herald), and the largest daily tabloid (Herald Sun). In this regard, article frequency containing specified keywords were contrasted between the periods 1990–2000 and 2001–2015; and article frequencies were benchmarked against frequencies of actual recorded terrorist activities (via the Global Terrorist Database), as measured through the number of attacks and the number of killed and wounded in the attacks. The data presented in the thesis indicates that most terrorist groups do not adhere to an Islamist ideology, and most terrorist attacks between 1990 and 2015 were undertaken by non-Islamist terrorist groups. It also indicates that Jihadi-Takfiri Neo-Salafism (often broadly referred to as Salafism/Wahhabism), the minority Islamic ideology that has been espoused by al-Qaeda and ISIS, is linked to the majority of Islamist terrorist organisations and their attacks. The data also suggests significant changes in reporting levels on Islam and terrorism since 2001. The conclusions drawn from the post-positivist quantitative analysis suggest there is resonance between this nomothetic approach and ideographic approaches represented in prior qualitative studies on representation of Islam and terrorism in the Western press. In this regard, findings support Orientalist theory. Due to the nature of circulation of international news in the West, it is likely that similar results would be obtained in other Western countries, however this needs testing -- abstract.
Additional file 10 of On the impact of relatedness on SNP association analysis
Creators: name: Gross, Arnd
name: Tรถnjes, Anke
name: Scholz, Markus
Publisher: name: figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Comparison of methods for modelling the polygenic effect. This file provides additional tables with inflation results for different polygenic models. (PDF 67 kb)
Production of human fucosyltransferases in Trichoderma reesei
Creators: name: Gryshyna, Anna
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Glycosylation is the most complex posttranslational modification specific to eukaryotes and also some bacteria. . One of the bottlenecks limiting progress in the glycobiology research is the non-availability and/or high price of glycan-modifying enzymes, such as fucosyltransferases, due to the imperfections of existing production systems. The aim of this project was to evaluate the potential of a filamentous fungus Trichoderma reesei as an expression host for recombinant human ɑ-1,3/4 fucosyltransferases (FUT3 and FUT4). The principles discovered and approaches used can be applied to other mammalian glycoproteins of biomedical interest. In the current work, cDNAs encoding the C-terminal catalytic domains of the human ɑ-1,3/4 fucosyltransferases were synthesised according to the T. reesei codon usage and assembled into expression vectors under the strong cellobiohydrolase 1 (cbh1) promoter. FUT3 and FUT4 were produced as a fusion to a Strep-tag, mCherry fluorescent protein and the core-linker fragment of the endogenous CBH1 protein to facilitate protein purification and secretion. Due to the better performance of the transformants producing the recombinant FUT3 protein, most of the work was carried out with the transformants producing FUT3, while the FUT4 protein was not studied in detail. Screening of T. reesei transformants demonstrated not only secretion of a fusion protein but also its degradation, most probably by the extracellular proteases of T. reesei. Protease inhibition studies suggested that the main protease damaging the recombinant FUT3 was a serine protease active at acidic pH. The recombinant protein was purified using a Strep-Tactin column, and the estimated yield of FUT3 was about 70 mg/l. N-terminal sequencing of purified proteins revealed that some of them were N-terminally blocked; one protease cleavage site was identified at the N-terminus of the mCherry protein. Cultivation of the T. reesei transformants at a neutral pH and with addition of a serine protease inhibitor PMSF demonstrated that degradation of the recombinant FUT3 in the culture supernatants could be suppressed. The activity of the purified recombinant FUT3 was assayed and preliminary results indicated that recombinant FUT3 has certain enzymatic activity although further studies are necessary to confirm these data. In conclusion, it was established that a recombinant human fucosyltransferase FUT3 could be produced in T. reesei. Further studies into optimisation of the cultivation conditions and strain development to limit the proteolytic degradation are required to achieve higher production levels.
Additional file 1: of Using patient data to optimize an expert-based guideline on convalescence recommendations after gynecological surgery: a prospective cohort study
Creators: name: Bouwsma, Esther
name: Anema, Johannes
name: A. Vonk Noordegraaf
name: Vet, Henrica De
name: Huirne, Judith
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: Overview of activities included in the developed convalescence guideline. (DOCX 16 kb)
Reducing Nondeterministic Tree Automata by Adding Transitions
Creators: name: Almeida, Ricardo Manuel de Oliveira
Publisher: name: arXiv
Year: 2016
Subjects: subject: Formal Languages and Automata Theory (cs.FL)
subject: FOS: Computer and information sciences

description: We introduce saturation of nondeterministic tree automata, a technique that consists of adding new transitions to an automaton while preserving its language. We implemented our algorithm on minotaut - a module of the tree automata library libvata that reduces the size of automata by merging states and removing superfluous transitions - and we show how saturation can make subsequent merge and transition-removal operations more effective. Thus we obtain a Ptime algorithm that reduces the size of tree automata even more than before. Additionally, we explore how minotaut alone can play an important role when performing hard operations like complementation, allowing to both obtain smaller complement automata and lower computation times. We then show how saturation can extend this contribution even further. We tested our algorithms on a large collection of automata from applications of libvata in shape analysis, and on different classes of randomly generated automata.
description: In Proceedings MEMICS 2016, arXiv:1612.04037
The Effect of Protoplanetary Disk Cooling Times on the Formation of Gas Giant Planets by Gravitational Instability
Creators: name: Boss, Alan P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Observational evidence exists for the formation of gas giant planets on wide orbits around young stars by disk gravitational instability, but the roles of disk instability and core accretion for forming gas giants on shorter period orbits are less clear. The controversy extends to population synthesis models of exoplanet demographics and to hydrodynamical models of the fragmentation process. The latter refers largely to the handling of radiative transfer in three dimensional (3D) hydrodynamical models, which controls heating and cooling processes in gravitationally unstable disks, and hence dense clump formation. A suite of models using the $β$ cooling approximation is presented here. The initial disks have masses of 0.091 $M_\odot$ and extend from 4 to 20 AU around a 1 $M_\odot$ protostar. The initial minimum Toomre $Q_i$ values range from 1.3 to 2.7, while $β$ ranges from 1 to 100. We show that the choice of $Q_i$ is equal in importance to the $β$ value assumed: high $Q_i$ disks can be stable for small $β$, when the initial disk temperature is taken as a lower bound, while low $Q_i$ disks can fragment for high $β$. These results imply that the evolution of disks toward low $Q_i$ must be taken into account in assessing disk fragmentation possibilities, at least in the inner disk, i.e., inside about 20 AU. The models suggest that if low $Q_i$ disks can form, there should be an as yet largely undetected population of gas giants orbiting G dwarfs between about 6 AU and 16 AU.
description: 40 pages, 10 figures, 1 table, accepted by ApJ
Multi-State Trajectory Approach to Non-Adiabatic Dynamics: General Formalism and the Active State Trajectory Approximation
Creators: name: Tao, Guohua
Publisher: name: arXiv
Year: 2017
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: A general theoretical framework is derived for the recently developed multi-state trajectory (MST) approach from the time dependent Schrödinger equation, resulting in equations of motion for coupled nuclear-electronic dynamics equivalent to Hamilton dynamics or Heisenberg equation based on a new multistate Meyer-Miller (MM) model. The derived MST formalism incorporates both diabatic and adiabatic representations as limiting cases, and reduces to Ehrenfest or Born-Oppenheimer dynamics in the mean field or the single state limits, respectively. By quantizing nuclear dynamics to a particular active state, the MST algorithm does not suffer from the instability caused by the negative instant electronic population variables unlike the standard MM dynamics. Furthermore the multistate representation for electron coupled nuclear dynamics with each state associated with one individual trajectory presumably captures single state dynamics better than the mean field description. The coupled electronic-nuclear coherence is incorporated consistently in the MST framework with no ad-hoc state switch and the associated momentum adjustment or parameters for artificial decoherence, unlike the original or modified surface hopping treatments. The implementation of the MST approach to benchmark problems shows reasonably good agreement with exact quantum calculations, and the results in both representations are similar in accuracy. The active state trajectory (AST) approximation of the MST approach provides a consistent interpretation to trajectory surface hopping, which predicts the transition probabilities reasonably well for multiple nonadiabatic transitions and conical intersection problems.
description: 41 pages, 7 Figures
Electromagnetic Cascades as Probes of Cosmic Magnetism
Creators: name: Batista, Rafael Alves
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The existence of intergalactic magnetic fields (IGMFs) is an open problem in cosmology and has never been unambiguously confirmed. High-energy gamma rays emitted by blazars are unique probes of cosmic magnetism, as their interactions with pervasive radiation fields generate a short-lived charged component sensitive to intervening magnetic fields. Spatial and temporal properties of the secondary gamma rays generated in the electromagnetic cascade can provide information about the strength, power spectrum, and topology of IGMFs. To probe these fields, detailed simulations of gamma-ray propagation in the intergalactic medium are necessary. In this work the effects of magnetic fields on the spectrum and arrival directions of gamma rays are studied using three-dimensional simulations, emphasising the particular case of helical IGMFs.
description: Proceedings of the 11th Workshop on Science with the New Generation of High Energy Gamma-ray Experiments (SciNeGHE 2016), 18-21 Oct 2016, Pisa, Italy
title: The Well-being of the Workforce during the COVID-19 Crisis: a mixed method study
Creators: name: Blake, Holly
name: Hassard, Juliet
name: Choo, Wei
name: Pickford, Rich
name: Thomson, Louise
name: Karanika-Murray, Maria
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Organization Development
subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: The study will aim to assess the impact of different types of work status (employed, self-employed, furloughed) during COVID-19 pandemic on well-being and organisational outcomes (commitment, turnover intention) and to examine the role of organisational and personal resources in preventing these outcomes (quantitative part). It will also explore the experience of changes to work status during COVID-19 and perceptions of how these have affected individuals (qualitative part)
New graph polynomials in parametric QED Feynman integrals
Creators: name: Golz, Marcel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In recent years enormous progress has been made in perturbative quantum field theory by applying methods of algebraic geometry to parametric Feynman integrals for scalar theories. The transition to gauge theories is complicated not only by the fact that their parametric integrand is much larger and more involved. It is, moreover, only implicitly given as the result of certain differential operators applied to the scalar integrand $\exp(-Φ_Γ/Ψ_Γ)$, where $Ψ_Γ$ and $Φ_Γ$ are the Kirchhoff and Symanzik polynomials of the Feynman graph $Γ$. In the case of quantum electrodynamics we find that the full parametric integrand inherits a rich combinatorial structure from $Ψ_Γ$ and $Φ_Γ$. In the end, it can be expressed explicitly as a sum over products of new types of graph polynomials which have a combinatoric interpretation via simple cycle subgraphs of $Γ$.
description: 24 pages, 3 figures
Cholesterol impairment contributes to neuroserpin aggregation
Creators: name: Giampietro, Costanza
name: Lionetti, Maria Chiara
name: Costantini, Giulio
name: Mutti, Federico
name: Zapperi, Stefano
name: La Porta, Caterina A. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cell Behavior (q-bio.CB)
subject: FOS: Biological sciences

description: Intraneural accumulation of misfolded proteins is a common feature of several neurodegenerative pathologies including Alzheimer's and Parkinson's diseases, and Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB). FENIB is a rare disease due to a point mutation in neuroserpin which accelerates protein aggregation in the endoplasmic reticulum (ER). Here we show that cholesterol depletion induced either by prolonged exposure to statins or by inhibiting the sterol regulatory binding-element protein (SREBP) pathway also enhances aggregation of neuroserpin proteins. These findings can be explained considering a computational model of protein aggregation under non-equilibrium conditions, where a decrease in the rate of protein clearance improves aggregation. Decreasing cholesterol in cell membranes affects their biophysical properties, including their ability to form the vesicles needed for protein clearance, as we illustrate by a simple mathematical model. Taken together, these results suggest that cholesterol reduction induces neuroserpin aggregation, even in absence of specific neuroserpin mutations. The new mechanism we uncover could be relevant also for other neurodegenerative diseases associated with protein aggregation.
description: 7 figures
Global identification in the cloud: a study of cloud passport model
Creators: name: Lam, Yuk-Tung Tonnie
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: In this research, we studied the idea of Cloud Passport, an initiative which uses the latest technologies to replace physical passports. Advantages and challenges of implementing a passport-less system for travel between countries were discussed. Different types of technology adoption models and research method were evaluated. A Cloud Passport adoption model was formulated as the basis for the current research. A convenient sample survey was conducted in February 2017 to Australian adult Facebook users to find out the social attitude on the proposal of Cloud Passport. Survey results showed that there was a 70% acceptance level on Cloud Passport. Social opinions on different technical components of Cloud Passport were also asked in the study. 75% of the interviewees thought that Cloud Passport would be available worldwide in the next 10 to 20 years. A textual analysis of the feedback from the survey discovered some drivers and barriers to the implementation of Cloud Passport. The observations from the surveys formed an overall view of the social opinion of a sample of Australians on the Cloud Passport initiative, which may help to contribute further study for an appropriate change management strategy for a successful roll-out of Cloud Passport in Australia.
Additional file 1: of Identifying lower limb specific and generalised joint hypermobility in adults: validation of the Lower Limb Assessment Score
Creators: name: Meyer, Kaitlin
name: Cliffton Chan
name: Hopper, Luke
name: Nicholson, Leslie
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: The Lower Limb Assessment Score. This file contains the name, patient and therapist instructions and criteria for each of the 12 tests of the Lower Limb Assessment score as described by the original authors that developed this tool. (DOCX 17 kb)
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome III, Cart. 187 (11 H 72), f. 0090v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome III, Archives départementales de la Côte-d'Or, Cart. 187 (11 H 72), f. 0090v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome III, Archives départementales de la Côte-d'Or, Cart. 187 (11 H 72), f. 0090v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Sending Money Like Sending E-mails: Cryptoaddresses, The Universal Decentralised Identities
Creators: name: Zima, Michal
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Sending money in cryptocurrencies is majorly based on public keys or their hashed forms -- "addresses." These long random-looking strings are user unfriendly for transferring by other means than via copy-and-paste or QR codes. Replacing such strings with identifiers chosen by users themselves would significantly improve usability of cryptocurrencies. Such identifiers could be memorable, easier to write on paper or to dictate over phone. Main challenge lies in designing a practically usable decentralised system for providing these identifiers. Former solutions have been built as centralised systems or come with nonnegligible limitations. Our solution is reminiscent of a prevalent e-mail system, which is an already user friendly and desirably decentralised system. It is shown that our approach is directly applicable also to other systems that use long cryptographic identifiers.
description: In Proceedings MEMICS 2016, arXiv:1612.04037
PREISTORIA DEL BUCOLICUM PETRARCHESCO II. UNA VARIANTE REDAZIONALE DI PARTHENIAS NELLA FAMILIARE X 4 AL FRATELLO GHERARDO
Creators: name: Cascio, Giovanni
Publisher: name: Università degli Studi di Messina.
Year: 2020

description: L’articolo si occupa, nel contesto di una più ampia riflessione sulla vicenda compositiva del Bucolicum carmen meum di Francesco Petrarca anteriormente alla trascrizione autografa del 1357 (oggi Città del Vaticano, Bibl. Apostolica Vaticana, Vat. lat. 3358), di un importante fossile redazionale dell’ecloga Parthenias (= Buc. carm. I) conservato nella Fam. X 4, lettera scritta presumibilmente nel dicembre del 1349 per il fratello Gherardo, con la quale l’autore forniva al destinatario un supporto esegetico per comprendere i significati della bucolica nascosti dietro la fitta trama allegorica. The article falls into a wider research on the redactional history of Bucolicum carmen meum by Francis Petrarch before the autograph transcription of the 1357 (today Città del Vaticano, Bibl. Apostolica Vaticana, Vat. lat. 3358). In particular, it deals with an important editorial fossil of the eclogue Parthenias (= Buc. carm. I) preserved by the letter Fam. X 4 addressed to Gherardo Petrarca presumably in December 1349, whereby the author provided his recipient with exegetical assistance to understand the allegorically encrypted meanings of the eclogue.
description: PELORO, Vol 4, N° 2 (2019)
Hydrothermal alteration within the Coalstoun Porphyry Copper Prospect, Gayndah, Queensland
Creators: name: Billington, W. G.
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The Coalstoun porphyry copper prospect lies adjacent to the north-northwest trending Perry Fault system. The intrusives of the prospect comprise porphyritic biotite ± hornblende quartz diorite and tonalites, their porphyritic microcrystalline equivalents and associated dykes. The composite intrusion appears to have attained shallow crustal levels which has produced fracturing and brecciation of the overlying, and surrounding sediments. Pervasive hydrothermal alteration / sulphide mineralization accompanied the final states of crystallization and culminated in the formation of veins and fracture fillings. The zonal pattern of this alteration / mineralization resulted in a deep core low in both copper and total sulphides, a surrounding biotite zone within which all significant copper mineralization occurs, and a fringe of chloritized - pyritized intrusive and surrounding metasediments. These alterations are almost isochemical, with dominant variations in K, Ca, Rb, Sr and Cu. Petrographic observations and microprobe analyses of hydrothermal biotites showed that they are characteristically different in composition and form to those of primary magmatic biotites, including lower Ti, lower total Fe as FeO, lower Fe/ Mg and Si / A1 ratios, and possibly an increase in the Fe3+ / Fe2+ ratio. They are much finer grained and possess a greenish colour to their pleochroism. A model is suggested to explain the high level of the intrusion, its effects upon the surrounding sediments, the association of copper mineralization and biotitization, the characteristics of this biotite, the surrounding chlorite zone and the subsequent veining and later andesitic-dacitic dyke emplacement. The model shows similarities to those proposed by Guilbert and Lowell (1974), and Carson and Jambor (1974).
Additional file 3: of Maternal variant in the upstream of FOXP3 gene on the X chromosome is associated with recurrent infertility in Japanese Black cattle
Creators: name: Arishima, Taichi
name: Sasaki, Shinji
name: Isobe, Tomohiro
name: Ikebata, Yoshihisa
name: Shimbara, Shinichi
name: Ikeda, Shogo
name: Kawashima, Keisuke
name: Suzuki, Yutaka
name: Watanabe, Manabu
name: Sugano, Sumio
name: Mizoshita, Kazunori
name: Sugimoto, Yoshikazu
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Genes in the QTL_3, 4, 5, 6 on the X chromosome in Japanese Black cattle. (a) Plot of regional SNPs of QTL_3 to _6. (b) The Ensembl IDs of genes are labeled at the left side of the plot. The details of Ensembl ID of genes are provided in Additional file 2: Table S2. (PDF 53 kb)
Secular dynamics of a planar model of the Sun-Jupiter-Saturn-Uranus system; effective stability into the light of Kolmogorov and Nekhoroshev theories
Creators: name: Giorgilli, Antonio
name: Locatelli, Ugo
name: Sansottera, Marco
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We investigate the long-time stability of the Sun-Jupiter-Saturn-Uranus system by considering a planar secular model, that can be regarded as a major refinement of the approach first introduced by Lagrange. Indeed, concerning the planetary orbital revolutions, we improve the classical circular approximation by replacing it with a solution that is invariant up to order two in the masses; therefore, we investigate the stability of the secular system for rather small values of the eccentricities. First, we explicitly construct a Kolmogorov normal form, so as to find an invariant KAM torus which approximates very well the secular orbits. Finally, we adapt the approach that is at basis of the analytic part of the Nekhoroshev's theorem, so as to show that there is a neighborhood of that torus for which the estimated stability time is larger than the lifetime of the Solar System. The size of such a neighborhood, compared with the uncertainties of the astronomical observations, is about ten times smaller.
description: 31 pages, 2 figures. arXiv admin note: text overlap with arXiv:1010.2609
Event marketing as an appropriately integrated marketingcommunication for promoting tourism of Ko Lad E-Tan,Nakhon Pathom Province, Thailand
Creators: name: Maslin Buaban
Publisher: name: Nakhon Pathom Rajabhat University
Year: 2019
Subjects: Event marketing, integrated marketing communication, agro tourism, Nakhon Pathom Province

description: Interdisciplinary Research Review, 14, 6, 36
Entretien de Waed Hamd al-Badur auprès de Munira Jibril Abdrabih al-Badur à propos du chemin de fer et du commerce durant la première guerre mondiale dans la région de Ma'an
Creators: name: al-Badur, Munira Jibril Abdrabih
name: Waed Hamd Al-Badur (Enquêtrice)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/FileId-3139
description: Coverage: Ma'an, Jordanie
FACTORS INFLUENCING COMPUTER USAGE AMONG HORTICULTURE FIRMS IN THE UNITED STATES
Creators: name: Posadas, C.
name: Posadas, C.
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Crop Production/Industries
subject: Production Economics
subject: Productivity Analysis
subject: Research and Development/Tech Change/Emerging Technologies
subject: Teaching/Communication/Extension/Profession
subject: Greenhouses
subject: socioeconomic
subject: survey
subject: automation
subject: economic recession

description: Empirical models describing the factors influencing the levels of computerization of the operations of nurseries and greenhouses in the United States were estimated using the data collected from a regional survey in the Southern States and two national surveys in the United States. The models measure the significant effects of the socioeconomic characteristics of managers and operational characteristics of firms to the level of computer use among nurseries and greenhouses. Results show that the socioeconomic characteristics of the participating owners and managers had exercised limited influence in the decisions involving the computerization of horticulture operations. The operational characteristics of the horticulture operations included in the surveys which have significant influences on the level of computerization included the number of workers hired, level of automation, annual gross sales, wholesale sales, years since establishment, and location. The recent Great Recession encouraged the participating firms to increase the use of computers in their operations.
A Light-Weight Approach for Verifying Multi-Threaded Programs with CPAchecker
Creators: name: Beyer, Dirk
name: Friedberger, Karlheinz
Publisher: name: arXiv
Year: 2016
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Programming Languages (cs.PL)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Verifying multi-threaded programs is becoming more and more important, because of the strong trend to increase the number of processing units per CPU socket. We introduce a new configurable program analysis for verifying multi-threaded programs with a bounded number of threads. We present a simple and yet efficient implementation as component of the existing program-verification framework CPAchecker. While CPAchecker is already competitive on a large benchmark set of sequential verification tasks, our extension enhances the overall applicability of the framework. Our implementation of handling multiple threads is orthogonal to the abstract domain of the data-flow analysis, and thus, can be combined with several existing analyses in CPAchecker, like value analysis, interval analysis, and BDD analysis. The new analysis is modular and can be used, for example, to verify reachability properties as well as to detect deadlocks in the program. This paper includes an evaluation of the benefit of some optimization steps (e.g., changing the iteration order of the reachability algorithm or applying partial-order reduction) as well as the comparison with other state-of-the-art tools for verifying multi-threaded programs.
description: In Proceedings MEMICS 2016, arXiv:1612.04037
"Big eye surgery" ;: understanding the ethical implications of medicalising Asian features in cosmetic surgery
Creators: name: Aquino, Yves Saint James
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: In East Asian countries, the ever-growing popularity of facial cosmetic surgery has generated various debates on the ethical implications of the practice. Ethical discussions are zooming in on the medicalisation of race-identifying facial features, such as Asian eyelids, in what has been referred to as Asian cosmetic surgery. In this study, I first posit that medicalisation in Asian cosmetic surgery can be interpreted in two forms: treatment versus enhancement forms. In the treatment form, cosmetic surgery is viewed as a remedy for "pathologised" Asian features. In the enhancement form, cosmetic surgery is seen as a form of improving the normal, albeit unwanted, racial features. Next, I present the findings from an empirical study that investigates medicalisation and its two forms in cosmetic surgery websites hosted in South Korea and Australia, as both countries are experiencing a growing number of aesthetic surgery clinics for Asians. Finally, I offer an ethical analysis of the consequences of medicalising racial features, mainly drawing from the findings of the empirical study. In particular, I describe how the practice influences individual autonomy and how it impacts on the traditional goals of medicine.
Additional file 5: of A systematic review of neonatal treatment intensity scores and their potential application in low-resource setting hospitals for predicting mortality, morbidity and estimating resource use
Creators: name: Jalemba Aluvaala
name: Collins, Gary
name: Michuki Maina
name: Berkley, James
name: English, Mike
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: Computational Biology

description: Summary of results from individual studies. Summary of data extracted from each eligible article. (DOCX 17Â kb)
Electron counting in solids: oxidation states, partial charges and ionicity
Creators: name: Walsh, Aron
name: Sokol, Alexey A.
name: Buckeridge, John
name: Scanlon, David O.
name: Catlow, C. Richard A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In this short viewpoint, we discuss the assignment of ionic charges in solids. We argue that formal oxidation states serve a useful function, and that absolute values of partial charges should be interpreted and applied with caution; the charge assigned can never be definitive and depends on the type of property studied and the type of analysis performed. Careful analysis can be used to avoid unphysical conclusions such as a recent report on the Ti(III) nature of Ti in stoichiometric TiO$_2$.