cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
BACnet/IT – Gebäudeautomation in Zeiten des Internets
Creators: name: Weck, Wolfgang
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2018
Subjects: subject: Internet of things
subject: automated testing
subject: building automation
subject: 600 - Technik
subject: 005 - Computer Programmierung, Programme und Daten

description: Über die letzten Jahrzehnte hat Datenkommunikation in verschiedenen Anwendungsbereichen Einzug gehalten und zu jeweils eigenen Lösungen geführt. So haben die Gebäudeautomations-Ingenieure für ihre Zwecke verschiedene Datennetzwerkstandards entwickelt, die sich in der Industrie und in bestehenden Gebäuden etabliert haben. Zugleich hat sich aus verschiedenen Anwendungen wie der Datenverarbeitung und der Büroinformation die bekannte Internet-Technologie entwickelt. Diese ist mittlerweile so verbreitet, dass eine Sogwirkung einsetzt: Dank hoher Stückzahlen, Marktmacht, Bekanntheit usw. wird es immer interessanter die Internet-Standards anstelle eigener, anwendungsspezifischer zu nutzen. Wie man zwei etablierte Standards – BACnet aus der Gebäudeautomation und die IT-Netze der Gebäude-Nutzer – zusammenbringen kann, ohne dass sich eine der beiden Welten komplett der anderen unterwirft, haben wir in einem KTI-geförderten Projekt zur Konvergenz der Gebäudeautomation und IT-Welt untersucht.
THE IMPACT OF STRENGTH TRAINING ACTIVITIES ON THE ENHANCEMENT OF SPEED IN SWIMMING FREESTYLE EVENTS
Creators: name: Ammar Muhi Khaleel Alghurabi
Publisher: name: Zenodo
Year: 2024

description: The current study aims to determine the impact of strength training on the growth of swimming speed in freestyle. Twenty male swimmers, aged 21 ± 2, from Physical Education and sport sciences department, the Islamic university in Najaf, Iraq, make up the sample for this study. Ten of them are in the experimental group and ten are in the control group. The experimental group received strength training on alternate days, or three sessions per week, including biceps curls, bench presses, front presses, back presses, and so on, while the control group received general training for eight weeks. 50-meter freestyle swimming was done for the pre- and post-tests in order to gauge speed. The dependent t-test was used to examine the impacts of strength training exercises for the development of speed among free style event swimmers. It was discovered that there was a significant difference in the speed of free style event swimmers at the 0.05 level of significance. This study demonstrates that the experimental group's 50-meter freestyle swimming performance has improved as a result of strength training when compared to the controlling group. To achieve at an elite level in swimming, strength training is crucial. In order to maximize the benefits of land-based training, we should choose exercises that are mechanically relevant to swimming, especially those that require the swimmer to push themselves through the water, like the arm pull and leg kick.
Comparison of infection-related hospitalization risk and costs in tumor necrosis factor inhibitor-experienced patients with rheumatoid arthritis (RA) treated with abatacept or other targeted disease-modifying anti-rheumatic drugs (tDMARDs)
Creators: name: Damemarie Paul
name: Dhaval Patil
name: McDonald, Laura
name: Vardhaman Patel
name: Lobo, Francis
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Background: Evidence on the cost and risk of infection-related hospitalizations associated with targeted disease-modifying anti-rheumatic drugs (tDMARDs) in patients with RA previously treated with a tumor necrosis factor inhibitor (TNFi) is limited. This study compared the risk and cost of infection-related hospitalizations in commercially insured TNFi-experienced RA patients receiving abatacept, TNFi, or another non-TNFi. Methods: A retrospective observational study was conducted using 2 large insurance claims databases (1 January 2009–30 June 2017). Adult TNFi-experienced RA patients initiating a subsequent tDMARD (initiation date of tDMARD = index date) with 12 months of continuous enrollment pre-index date, and who had ≥1 inpatient or ≥2 outpatient medical RA claims on 2 different dates were included. Abatacept was compared to TNFis (adalimumab, certolizumab pegol, etanercept, golimumab, and infliximab) and other non-TNFis (tocilizumab, rituximab, and tofacitinib). Cox proportional hazards models estimated the adjusted risk for infection-related hospitalization; costs were calculated on a per-member-per-month (PMPM) and per-patient-per-month (PPPM) basis using generalized linear models. Results: More patients in the abatacept cohort had an infection-related hospitalization at baseline (4.5%) vs TNFis (2.0%, p p = .2619). However, during follow-up abatacept patients had fewer infection-related hospitalizations (abatacept: 2.8%, TNFi: 3.7% and other non-TNFis: 5.2%; p p = .042), and other non-TNFi ($73 vs. $125; p = .039). Conclusions: There were significantly lower infection-related hospitalizations and associated costs in TNF-experienced RA patients treated with abatacept than TNFis and other non-TNFis.
The cost effectiveness of pembrolizumab versus chemotherapy or atezolizumab as second-line therapy for advanced urothelial carcinoma in the United States
Creators: name: Slater, Rachael Louise
name: Yizhen Lai
name: Yichen Zhong
name: Haojie Li
name: Meng, Yang
name: Moreno, Blanca Homet
name: Godwin, James Luke
name: Frenkl, Tara
name: Guru P. Sonpavde
name: Ronac Mamtani
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Aims: Pembrolizumab demonstrated significantly prolonged overall survival (OS) vs. chemotherapy in the Phase III KEYNOTE-045 trial, and is approved in the US for the treatment of patients with locally advanced or metastatic urothelial carcinoma (mUC) who progressed after platinum-based chemotherapy. Using longer follow-up and individual patient-data from KEYNOTE-045, this study evaluates the cost-effectiveness of pembrolizumab vs. chemotherapy or atezolizumab from a US payer perspective. Materials and methods: A partitioned-survival model was developed over a 20-year time horizon. Progression-free survival (PFS) and OS for pembrolizumab and chemotherapy were extrapolated using a piecewise modelling approach, where patient-level data from KEYNOTE-045 were used for the initial period followed by parametric distributions. OS of atezolizumab was estimated by indirect treatment comparisons based on KEYNOTE-045 and IMvigor211. Different scenarios were explored in the absence of indirect comparisons on PFS and time-on-treatment (ToT) between pembrolizumab and atezolizumab. Drug acquisition/administration, disease management, adverse events, and terminal care costs were considered. Results: Compared with chemotherapy, pembrolizumab resulted in a mean gain of 1.33 life-years and 1.14 quality-adjusted life-years (QALYs) and an incremental cost of $106,299, yielding an incremental cost-effectiveness ratio of $93,481/QALY gained. Pembrolizumab dominated atezolizumab in extending patients’ life by 0.89 years and 0.76 QALYs, while reducing costs by $26,458. Key drivers of cost-effectiveness included survival extrapolation, OS hazard ratio of pembrolizumab vs. atezolizumab, and time horizon. Pembrolizumab had a 66% and 100% probability of being cost-effective vs. chemotherapy and atezolizumab, respectively, at a $100,000 willingness-to-pay threshold. Limitations and conclusions: Uncertainties remain with extrapolated PFS and OS for pembrolizumab, OS indirect comparison, and ToT for atezolizumab. Despite these limitations, the model used robust methods to estimate key clinical endpoints with patient-level data from longer follow-up of KEYNOTE-045. Pembrolizumab dominates atezolizumab and is very likely cost-effective vs. chemotherapy in 2 L mUC at a $100,000 willingness-to-pay threshold.
Estimating health state utilities associated with a rare disease: familial chylomicronemia syndrome (FCS)
Creators: name: Matza, Louis S.
name: Phillips, Glenn A.
name: Howell, Timothy A.
name: Ciffone, Nicole
name: Ahmad, Zahid
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Aims: Familial chylomicronemia syndrome (FCS) is a rare genetic disorder with no currently approved therapies. Treatments are in development, and cost-utility analyses will be needed to examine their value. These models will require health state utilities representing FCS. Therefore, the purpose of this study was to estimate utilities for FCS and an associated episode of acute pancreatitis (AP). Methods: Because it is not feasible to gather a large enough sample of patients with this extremely rare condition to complete standardized preference-based measures, vignette-based methods were used to estimate utilities. In time trade-off interviews, general population participants in the UK and Canada valued health state vignettes drafted based on literature review, clinician input, and interviews with patients. Four health states described variations of FCS. A fifth health state, describing AP, was added to one of the other health states to evaluate its impact on utility. Results: A total of 308 participants provided utility data (208 UK; 100 Canada). Mean utilities for FCS health states ranged from 0.46 to 0.83, with higher triglycerides, more severe symptoms, and a history of AP associated with lower utility values. The disutility (i.e. utility decrease) of AP ranged from –0.17 to –0.25, with variations depending on the health state to which it was added. Utility means were similar in the UK and Canada. Conclusions: The vignette-based approach is useful for estimating utilities of a rare disease. The health state utilities derived in this study would be useful in models examining cost-effectiveness of treatments for FCS.
title: ADCO, Premier cartulaire de Saint-Étienne de Dijon (XIIe siècle), Cart. 21 (G 125), 71 folios, f. 00111
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: cartulaire
subject: Chartes de la Bourgogne du Moyen Âge

description: Premier cartulaire de Saint-Étienne de Dijon (XIIe siècle), Archives départementales de la Côte-d'Or, Cart. 21 (G 125), 71 folios, f. 00111, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Premier cartulaire de Saint-Étienne de Dijon (XIIe siècle), Archives départementales de la Côte-d'Or, Cart. 21 (G 125), 71 folios, f. 00111, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Assessing the burden of nocturia in the workplace: The associations between nocturnal voiding, subjective well-being, work engagement and productivity
Creators: name: Hafner, Marco
name: Andersson, Fredrik L.
name: Burtea, Teodor
name: Stolk, Christian Van
name: Whitmore, Michael
name: Yerushalmi, Erez
name: Troxel, Wendy M.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Aims: Nocturia (getting up at night to urinate, where each urination being followed by sleep or intention to sleep) is a bothersome symptom with potentially negative consequences for individual health and daytime functioning. This study assessed the burden of nocturia in the workplace by investigating associations between nocturia and subjective well-being, work engagement and productivity. Methods: Using large-scale international workplace survey data, the associations between nocturia, subjective well-being (SWB), work engagement (Utrecht Work Engagement Scale, UWES-9) and productivity (Work Productivity and Impairment Index, WPAI) were assessed. Bivariate and multivariate regression analysis was used with adjustment for a large set of confounding factors, including sleep duration and sleep quality. Results: Across a study sample of 92,129 observations, aged 18 to 70, an average of 10% of the survey population reported ≥2 nocturnal voids (generally considered clinically significant nocturia), with prevalence of nocturia increasing with age. Individuals with nocturia reported a 35.7% (p Conclusions: A key contribution of this study is the assessment of the association between nocturia and a range of work performance outcomes in a sizeable study using validated instruments to measure work engagement and productivity. The study highlights the importance of taking sleep into account when assessing the relationship between nocturia and associated outcomes.
Roboter Nao Senior Solution - Einsatz sozialer Roboter zur Aktivierung von Seniorinnen und Senioren: Erkenntnisse aus einer Feldstudie in 4 Alters- und Pflegeheimen
Creators: name: Schulze, Hartmut
name: Tanner, Alexandra
name: Urech, Andreas
name: Gostanian, Jean Christophe
name: Bohler, Gabriela
Publisher: name: Hochschule für Angewandte Psychologie FHNW
Year: 2020
Subjects: subject: Soziale Roboter
subject: Mensch-Roboter-Interaktion
subject: Roboter in der Pflege
subject: Aktivierung
subject: 100 - Philosophie und Psychologie
subject: 300 - Sozialwissenschaften
subject: 600 - Technik, Medizin, angewandte Wissenschaften

description: Aktivierungsstunden in der Altenpflege haben sich in den Pflegeinstitutionen etabliert. Ziel dabei ist die Förderung der körperlichen, geistigen, sozialen und emotionalen Fähigkeiten von betagten Personen. Die Schweizer Robotik Firma Avatarion hat eine Software für einen sozialen Roboter mit Aktivierungsübungen in der Altenpflege entwickelt. Im Rahmen einer Feldstudie in vier verschiedenen Pflegezentren wurden fünf Aktivierungsstunden mit 15 – 20 Teilnehmenden pro Stunde begleitet. Dabei wurden teilnehmende Beobachtungen mit Videoaufzeichnung ausgeführt. Ziel der Untersuchung war es zu erheben, ob sich betagte Personen an einer Aktivierungsstunde angeleitet durch einen sozialen Roboter beteiligen und welche Aspekte eine Teilnahme an der Übung initiieren oder hindern. Zusätzlich wurde im Rahmen der Feldstudie erfragt, wie das Aktivierungsfachpersonal und wie Leitungspersonen über einen Robotereinsatz in diesem Gebiet denken und welches Verbesserungspotential die Software aufweist. Die Ergebnisse zeigen auf, dass Seniorinnen und Senioren engagiert an einer Aktivierungsstunde vermittelt durch einen sozialen Roboter mitmachen. Gymnastikübungen erhielten besonderen Anklang, es wurden Lieder mit dem Roboter gesungen und die Teilnehmenden reagierten sichtbar auf Inhalte der Geschichten, die der Roboter erzählte. Einzelne Verhaltensweisen des Roboters förderten eine Teilnahme, wie beispielsweise „direktes Ansprechen“ oder das „Aufstehen und Hinsetzen“. Die Gespräche mit dem Personal aus den Altersheimen zeigten eine positive Einstellung gegenüber der neuen Methode für Aktivierungsstunden auf. Aktivierungsfachpersonen schätzten den Roboter als Unterstützung für eine Aktvierungsstunde ein. Leitungspersonen erkannten Potenziale u.a. für das Ressourcenmanagement. Beispielsweise hätte das Pflegepersonal mehr Zeit, die eilnehmenden zu fördern während der Roboter eine Übung vorzeigt. Auch wurde eine Entlastung infolge eines reduzierten Vorbereitungsaufwands gesehen. Als Hürden wurden der als relativ hoch eingeschätzte Aufwand inkl. Anschaffungskosten zu Beginn, Bedenken bezüglich der Benutzerfreundlichkeit und Supportaufwänden sowie Befürchtungen von Arbeitsplatzverlust beschrieben.
Pandanus and changing site use: A study from Manim Valley, Papua New Guinea
Creators: name: Donoghue, Debra
Publisher: name: Zenodo
Year: 1988
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database

description: The value of an anthropological approach to archaeology is becoming increasingly appreciated. This thesis uses an ethno-archaeological focus to investigate the spatial and temporal variations which appear in the Pandanus nut assemblages from four rockshelter sites in Manim Valley, Papua New Guinea. I develop a "Site Use Model" which predicts the nature of the Pandanus assemblages based on hunter-gatherer subsistence and settlement strategies and previous interpretations of the sites’ functions and field observations of Pandanus use. The Model is tested against the Pandanus nut remains from the sites. The test concludes that the morphologicaldifferences between the Pandanus nuts are not a result of the domestication process but probably represent the habitat preference of the Pandanus species. The functions occurring at the sites do change over time, but cannot be explained alone by the spread of agriculture. It is suggested that the composition of groups using the sites adds to the complexity of the issue.
description: Thesis submitted to the Department of Anthropology and Sociology, University of Queensland for a Master of Arts Degree (122 p)
The archaeology of Rossel Island, Massim, Papua New Guinea: Towards a prehistory of the Louisiade Archipelago
Creators: name: Shaw, Ben
Publisher: name: Zenodo
Year: 2014
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database

description: The research presented in this thesis is focused on the archaeology of Rossel Island, the easternmost island in the Milne Bay Province, otherwise known culturally as the Massim. Rossel Island is one of the larger islands in the Louisiade Archipelago, and situated 400km from the mainland it is also one of the most isolated islands in the region. The people on the island today speak a Non-Austronesian language that is unrelated to the Austronesian languages spoken elsewhere in the Massim. The complexities of their cultural traditions are also regionally unparalleled and the people themselves are genetically distinct. Rossel Island is therefore seen as a unique outlier in the Massim region. ...
description: A thesis submitted for the degree of Doctor of Philosophy of the Australian National University (439)
title: Exacta Totius Hispaniæ Tabula; Annô hôc intercalari MDCCIIII
title: Cum Privilegio. Potentiß. D. D. Ordinum. Hollandiae et West-frisiae : met Previlegie van haar Ed: Groot Mog. de Staaten van Holland en West-vriesland
titleType: Subtitle
Creators: name: Valck, Gerard
name: Berge, Pieter van den
name: Schut, Pieter Hendricksz
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2023

description: Beigefügt "Descriptio Geographica totius Regni Hispaniae" und 14 Stadtansichten (Regiæ Madritensis; Toletum; Malaca; Barcelona; [Sevilla]; [Bellem]; Regis Lusitanorum aula; Caroli Tertii, Hispaniarum regius justi palatium, Olisipone; Conimbrica; Burgos; Barcano; Gades; Velusum Malaccæ; Petri, Lusitanorum regis palatium)
Eating Stone and Dying: Archaeological Survey on Woodlark Island, Milne Bay Province, Papua New Guinea
Creators: name: Bickler, Simon Hillel
Publisher: name: Zenodo
Year: 1998
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database

description: This dissertation describes the results of an archaeological survey carried out between 1995 and 1996 on Woodlark Island (Muyuw), in Milne Bay Province of Papua New Guinea. Woodlark Islanders have played an important role in the famous Kula exchange network which binds many of the islands of Milne Bay Province into a regional system. This dissertation has produced several dramatic new results. The data presented here include the first description of settlement of a large island in the Massim during the last two millennia. It includes the first detailed pottery sequence for Woodlark, and for the northern Massim more generally. ...
description: A Dissertation Presented to the Graduate Faculty of the University of Virginia in Candidacy for the Degree of Doctor of Philosophy Department of Anthropology University of Virginia
Building and Remembering: Constructing Ancestral Place at Popo, Orokolo Bay, Papua New Guinea
Creators: name: Urwin, Christopher David
Publisher: name: Zenodo
Year: 2018
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database

description: Orokolo Bay, located in the Gulf of Papua (Papua New Guinea), is a place well known to anthropology for its elaborate social and ceremonial life. Early colonial observers were struck by the large villages and vast longhouse structures that sustained decade-spanning ceremonies and annual long-distance exchanges (called hiri) in which seafaring traders from today’s Port Moresby region would bring ceramic pots and shell valuables for sago palm (Metroxlyon sagu) starch and hulls for their ships. However, the history of large coastal trading communities in the Gulf of Papua is poorly understood. ...
description: A thesis submitted for the degree of Doctor of Philosophy at Monash University in December 2018 Monash Indigenous Studies Centre (455 p)
Subscriber continuity in health insurance plans: factors associated with re-enrollment and coverage changes
Creators: name: Roberts, Melissa H.
name: Xuanhao He
name: Fuentes, Claudia Díaz
name: Edwardson, Nicholas
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Aims: This study examined the extent to which Marketplace health insurance subscribers re-enroll a second year. Among re-enrollees, we sought to examine movement to more and less generous insurance plans (based on actuarial value), and the extent to which adverse selection, adverse retention, and aging in place are evident from re-enrollment choices made. Methods: Re-enrollment from 2015 to 2016 and 2016 to 2017 and movement to more and less generous insurance plans was examined using enrollment and insurance claims data from two US Federally-facilitated Marketplace insurance carriers operating in the state of New Mexico for 2015–2017. Insurance plans are assigned to metal levels based on estimated plan actuarial value: Bronze (60%), Silver (70%), and Gold (80%). Odds ratios (ORs) and 95% confidence intervals (OR CI) were estimated using logistic regressions for subscribers with base-year healthcare utilization. ORs were estimated for (1) re-enrollment in the year following the base year, and (2) movement to a higher or lower actuarial value plan. Results: Approximately 50% of subscribers re-enrolled with the same carrier for 2016 and 60% for 2017. Being enrolled 12 months was the strongest predictor for second year re-enrollment. Older individuals were more likely to re-enroll. Re-enrollment was lower for the insurance carrier with higher second year premium changes. Chronic condition utilization characteristics were positively associated with re-enrollment. Approximately 12% of Bronze subscribers moved to Silver or Gold, and had higher utilization after re-enrollment. Among Silver subscribers, 6% moved to Gold and 6% to Bronze. Approximately 37% of Gold subscribers moved to Silver or Bronze. Discussion: Re-enrollment was similar to published non-group insurance rates. Adverse selection and aging in place were observed. Evidence was weak for adverse retention. Some coverage change choices were rational, while others suggest subscribers may have difficulty making insurance choice decisions.
Schulentwicklung. Rückblicke und Ausblicke. Editorial
Creators: name: Krainz-Dürr, Marlies
name: Jesacher-Rößler, Livia
name: Tulowitzki, Pierre
Publisher: name: StudienVerlag
Year: 2022
Subjects: subject: Bildungsreform
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Das Editorial leitet ein Jubiläum ein: Vor 25 Jahren wurde das journal für schulentwicklung gegründet. Die Ausgabe ist dabei Rück- und Ausblick gleichermaßen. Die Beiträge behandeln konkrete Themen wie die Genese von Schulautonomie oder den Status Quo der Fort- und Weiterbildung, widmen sich jedoch auch kritischen Anliegen wie Bildungsdisparitäten oder dem Geschlecht im Zusammenhang mit Führung.
title: L'Amerique Divisée En Tous Ses Pays Et Etats; 1760
title: Dressée Sur de Nouveaux Memoires et Sur les dernieres Observations ; Avec approbation et Privilège du Roy 1754
titleType: Subtitle
Creators: name: Longchamp, Sébastian G.
name: Janvier, Jean Denis
name: Chambon, Gobert-Denis
name: Chambon, Gobert-Denis
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2023

description: Osten oben, Titelkartusche unten rechts, eine Nebenkarte "Petite Mappe Monde" unten Mitte, auf dem Kartenrahmen 17 Darstellungen mit Erläuterungen
Hornhautsensibilität Teil 2: Der Einfluss von Kontaktlinsen
Creators: name: Nosch, Daniela
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2014
Subjects: Cornea
Hornhautsensibilität

description: Die Messung der Hornhautsensibilität ermöglicht eine Beurteilung der Funktionstüchtigkeit der schmerzempfindlichen oberflächlichen Hornhautnerven. Daraus ergeben sich wichtige Hinweise auf die Gesundheit der Hornhaut im Verlauf eines Erkrankungsprozesses, während der Heilungsphase nach einer Verletzung oder einem refraktiv-chirurgischen Eingriff, sowie beim Kontaktlinsentragen. Die Nervenenden in der Hornhaut und Bindehaut sind über ein komplexes Feedback-Netzwerk (unter Aktivierung von Hirnstamm Regelkreisen) mit den Tränendrüsen und dem Musculus orbicularis oculi verbunden, um die Gesundheit der Augenvorderfläche und den Tränenfilm jederzeit zu überwachen und zu erhalten. Für die Regulierung des Heilungsprozesses nach Verletzungen lösen sie die Freigabe von trophischen Substanzen (Neuropeptide und Neurotrophine) aus. Dieser Beitrag fasst die publizierte Literatur über den Einfluss des Kontaktlinsentragens zusammen und erläutert, welche Auswirkungen verschiedene Kontaktlinsenmaterialien und Tragemodi haben.
Cost of macrovascular complications in people with diabetes from a public healthcare perspective: A retrospective database study in Brazil
Creators: name: Julian, Guilherme Silva
name: Campos, Daniel
name: Honore, Julie Broe
name: Tobaruella, Flávia Sauer
name: Yoon, Jung Hyun
name: Hallén, Nino
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Aims: To evaluate costs in patients with diabetes who experienced a macrovascular complication from a Brazilian public healthcare system perspective. Materials and methods: A retrospective, observational study that utilized the database of the Brazilian Unified Health System (DATASUS). Data for direct medical costs (hospitalisation and outpatient) were extracted for patients with diabetes and a macrovascular complication (1 January 2012–31 December 2018) and converted to United Stated Dollars (2019 USD). Mixed-effects logistic regression explored associations between demographic and clinical characteristics with the incurrence of high direct medical costs. Results: In total, 1668 (0.2%) patients with diabetes met study inclusion criteria and experienced a macrovascular complication, either alone (N = 1193) or together with a microvascular complication (N = 475). Median [95% CI] annual costs (USD/patient) were 130.5 [90.7; 264.2] at baseline, increasing to 334.0 [182.2; 923.5] in the first year after the complication. The odds of incurring high costs were significantly elevated in the first and second year (vs. baseline), and in patients who experienced a macrovascular and microvascular complication (vs. macrovascular alone) (all p Limitations: The DATASUS database does not cover primary care (it covers secondary and tertiary care), adding a selection bias to the sample. Additionally, our findings may not be representative of the entire Brazilian population given that approximately 75% of the population of Brazil depend exclusively on the SUS, while the remaining 25% have some access to private healthcare. Conclusions: This study has demonstrated higher medical costs from the perspective of the Brazilian public healthcare system in patients with diabetes after experiencing a macrovascular complication, either alone or in conjunction with a microvascular complication, in comparison with costs before the complication(s). In addition to providing up-to-date cost estimates, our findings highlight the need to implement strategies to reduce the cardiovascular risk in Brazilian patients with diabetes and drive cost savings.
The pottery bowls from the Motupore excavation 1979-1983
Creators: name: Cox, Gillian
Publisher: name: Zenodo
Year: 1989
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database

description: As White and O'Connell point out the pottery recoveries from excavations on the Central Papuan Coast have yet to receive the extensive analysis and the required degree of detailed publication necessary to make comparative studies a viable proposition. It seems pointless to debate chronology without a precise knowledge of the ceramic assemblage at each and every site. Mindful of this situation, and whilst attempting the problem of utilizing ceramic bowl recoveries to correlate the complex midden stratigraphy from just one of the unpublished excavations, I have endeavoured to provide sufficiently detailed description and illustration from the Motupore 1979-1983 rescue excavation to take the first step towards the creation of a general information base upon which to build future comparative ceramic studies of the region.
description: 94 pages
SUM OF POWERS OF NATURAL NUMBERS USING  GENERATING FUNCTION
Creators: name: V. R. Kalyan Kumar* & Dr. R. Sivaraman**
Publisher: name: Zenodo
Year: 2024

description: Sum of powers of Natural numbers could be determined using various techniques and these techniques have fascinated mathematicians across the globe since ancient times. In this paper we are going to present one technique of determining sum of powers of natural numbers using a generating function defined explicitly. Some new formulas were established and using them, we have explained how to evaluate the sum of powers of natural numbers.
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00389
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00389, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
The cost effectiveness of pembrolizumab versus chemotherapy or atezolizumab as second-line therapy for advanced urothelial carcinoma in the United States
Creators: name: Slater, Rachael Louise
name: Yizhen Lai
name: Yichen Zhong
name: Haojie Li
name: Meng, Yang
name: Moreno, Blanca Homet
name: Godwin, James Luke
name: Frenkl, Tara
name: Guru P Sonpavde
name: Ronac Mamtani
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: AIMS: Pembrolizumab demonstrated significantly prolonged overall survival (OS) vs. chemotherapy in the Phase III KEYNOTE-045 trial, and is approved in the US for the treatment of patients with locally advanced or metastatic urothelial carcinoma (mUC) who progressed after platinum-based chemotherapy. Using longer follow-up and individual patient-data from KEYNOTE-045, this study evaluates the cost-effectiveness of pembrolizumab vs. chemotherapy or atezolizumab from a US payer perspective. MATERIALS AND METHODS: A partitioned-survival model was developed over a 20-year time horizon. Progression-free survival (PFS) and OS for pembrolizumab and chemotherapy were extrapolated using a piecewise modelling approach, where patient-level data from KEYNOTE-045 were used for the initial period followed by parametric distributions. OS of atezolizumab was estimated by indirect treatment comparisons based on KEYNOTE-045 and IMvigor211. Different scenarios were explored in the absence of indirect comparisons on PFS and time-on-treatment (ToT) between pembrolizumab and atezolizumab. Drug acquisition/administration, disease management, adverse events and terminal care costs were considered. RESULTS: Compared with chemotherapy, pembrolizumab resulted in a mean gain of 1.33 life-years and 1.14 quality-adjusted life-years (QALYs) and an incremental cost of $106,299, yielding an incremental cost-effectiveness ratio of $93,481/QALY gained. Pembrolizumab dominated atezolizumab in extending patients’ life by 0.89 years and 0.76 QALYs, while reducing costs by $26,458. Key drivers of cost-effectiveness included survival extrapolation, OS hazard ratio of pembrolizumab vs. atezolizumab and time horizon. Pembrolizumab had a 66% and 100% probability of being cost-effective vs. chemotherapy and atezolizumab, respectively, at a $100,000 willingness-to-pay threshold. LIMITATIONS AND CONCLUSIONS: Uncertainties remain with extrapolated PFS and OS for pembrolizumab, OS indirect comparison and ToT for atezolizumab. Despite these limitations, the model used robust methods to estimate key clinical endpoints with patient-level data from longer follow-up of KEYNOTE-045. Pembrolizumab dominates atezolizumab and is very likely cost-effective vs. chemotherapy in 2L mUC at a $100,000 willingness-to-pay threshold.
title: ADCO, Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Cart. 143 (7 H 7), 153 fol, f. 0119v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0119v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0119v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Molesme
description: Provenance: http://www.wikidata.org/entity/Q334044
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb137389344
Estimating health state utilities associated with a rare disease: Familial chylomicronemia syndrome (FCS)
Creators: name: Matza, Louis S.
name: Phillips, Glenn A.
name: Howell, Timothy A.
name: Ciffone, Nicole
name: Ahmad, Zahid
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Aims: Familial Chylomicronemia Syndrome (FCS) is a rare genetic disorder with no currently approved therapies. Treatments are in development, and cost-utility analyses will be needed to examine their value. These models will require health state utilities representing FCS. Therefore, the purpose of this study was to estimate utilities for FCS and an associated episode of acute pancreatitis (AP). Methods: Because it is not feasible to gather a large enough sample of patients with this extremely rare condition to complete standardized preference-based measures, vignette-based methods were used to estimate utilities. In time trade-off interviews, general population participants in the UK and Canada valued health state vignettes drafted based on literature review, clinician input, and interviews with patients. Four health states described variations of FCS. A fifth health state, describing AP, was added to one of the other health states to evaluate its impact on utility. Results: A total of 308 participants provided utility data (208 UK; 100 Canada). Mean utilities for FCS health states ranged from 0.46 to 0.83, with higher triglycerides, more severe symptoms, and a history of AP associated with lower utility values. The disutility (i.e., utility decrease) of AP ranged from -0.17 to -0.25, with variations depending on the health state to which it was added. Utility means were similar in the UK and Canada. Conclusions: The vignette-based approach is useful for estimating utilities of a rare disease. The health state utilities derived in this study would be useful in models examining cost-effectiveness of treatments for FCS.
Prehistoric culture change in the Port Moresby region
Creators: name: Bulmer, Susan Evelyn
Publisher: name: Zenodo
Year: 1987
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database

description: The thesis is a study of archaeological evidence from the vicinity of Port Moresby, the results of fieldwork between 1968 and 1972. Survey data from 95 archaeological sites, surface collections of potsherds and stone artefacts from 67 of these, and data from three archaeological excavations are analysed and compared. The evidence shows that the local population was formerly living in different places, that communities therefore were positioned differently in respect to local ecological zones, particularly the inland river plains, and that they formerly used a markedly different style of pottery. The thesis examines questions of the possible cause of changes to settlement patterns, ecology, and pottery styles resulting in the situation known from the late 19th century. Oral histories of the Koita and Motu are considered for the light they cast on past inter-communty variation and change. These traditions suggest that the situation of the late Proto-historic period, of heavy dependence upon imported food based on the specialist manufacture of shell ornaments and pottery, was of relatively recent origin. The archaeological evidence tends to support this iew. Three archaeological excavations directed by the author, at Nebira and Eriama, about 10 km inland near the Laloki River, and at Taurama on the coast, provide some direct evidence of change in pottery style and ecological orientation, while the survey data enables a reconstruction of past settlement patterns through pottery style changes. The pottery style sequence i sput into three general periods of time: an Early period, from about 2,000 to 1,000 years ago, a Middle period from about 1,000 to 1,500 A.D., and a Proto-historic period from about 1500 A.D. to the late 19th century. ...
description: A thesis submitted for the degree of Doctor of Philosophy in the Department of Anthropology and Sociology; University of Papua NewGuinea (495 p)
title: L'Europe Divisée En Tous Ses Etats; 1760
title: Dressée Sur de Nouveaux Memoires et Suivant les dernieres Observations ; Avec approbation et Privilège du Roy 1754
titleType: Subtitle
Creators: name: Longchamp, Sébastian G.
name: Janvier, Jean Denis
name: Chambon, Gobert-Denis
name: Chambon, Gobert-Denis
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2023

description: Titelkartusche oben links, auf dem Kartenrahmen 17 Darstellungen mit Erläuterungen
title: Si isotope thermometry in silicified carbonate
Creators: name:  Tatzel ,  Michael
name:  Oelze ,  Marcus
name:  Liesegang ,  Moritz
name:  Stuff ,  Maria
name:  Wiedenbeck ,  Michael
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Cherts, including silicified carbonates, are one of the most detailed and alteration resistant archives of near-surface environments. Yet, the information disclosed in form of stable isotope ratios of Si and O cannot be confidently translated into conditions prevailing at the Earth surface in deep time. Thermometry based on δ18O is compromised by the lack of knowledge about the fluid’s δ18O value and attempts to determine Si sources or temperatures from δ30Si remain unsatisfying. We investigated carbonate silicification in a Lower Cambrian silicified zebra dolomite that we analyzed for δ30Si by laser ablation MC-ICP-MS and δ18O using SIMS. Successively replaced carbonate layers show systematically decreasing δ18O values from 14.4 to 13.4 ‰ and systematically decreasing δ30Si values from 0.9 ‰ to ca. -2.0 ‰. We show that quantitative Si precipitation in a closed system best explains these data, requiring positive ε30Si values, which has long been proposed for thermodynamic equilibrium using ab-initio models. We exploit the modal abundances of the successively formed silica phases to quantify the fractional Si depletion from the fluid and to infer the Ɛ30Si values. Using a temperature calibration based on an ab-initio model (Dupuis et al., 2015), we determine the temperatures of carbonate replacement to be approx. 60°C and calculate the fluid δ18O to have been approx. -11 ‰, which is consistent with a meteoric water source. This approach opens a new avenue for determining initial fluid δ18O values in deep time and could thus solve long-standing disputes about hot vs. temperate Precambrian oceans.
title: Solid Earth applications of global gravity data: from submarines to satellites
Creators: name:  Root ,  Bart
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Prof. Vening Meinesz opened up the oceans for high precision gravimetric observations. Today, his submarine adventures are an inspiration to my science and education in gravimetric research. We will follow him along his voyage aboard the K18, along which I will discuss several applications using global gravity field models. The theory of isostasy allows us the use the static gravity field to study GIA processes in Fennoscandia and North America. Also, observed crustal structure from active seismic experiments can be used to correct the gravity field and study the upper mantle. With a regional crustal model of the British Isles and surrounding oceans I was able to study the density variations in the lithospheric mantle underneath the crust. This study revealed a highly varying upper mantle density signature, but compared with seismic tomography large differences were seen. We show that this mismatch can be traced back to regularisation techniques used in seismology. This opened up the study of mantle convection and its interaction with lithosphere. Seismic-derived mantle anomalies are still highly uncertain but might be improved with future gravity-rate datasets. Preliminary studies show potential in reducing the uncertainty in viscosity structure of the Earth. Finally, with the GOCE mission, a new boost has been given to the use of gravity gradients, I discuss an approach in inverting the full gravity gradient tensor estimating density structure of a subducting plate. By showing this variety of studies, I hope to inspire you to use satellite-derived global gravity fields.
Subscriber continuity in health insurance plans: factors associated with reenrollment and coverage changes
Creators: name: Roberts, Melissa H.
name: Xuanhao He
name: Fuentes, Claudia Díaz
name: Edwardson, Nicholas
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Aims: In this study we examined the extent to which Marketplace health insurance subscribers reenroll a second year. Among reenrollees, we sought to examine movement to more and less generous insurance plans (based on actuarial value), and the extent to which adverse selection, adverse retention, and aging in place are evident from reenrollment choices made. Methods: Reenrollment from 2015 to 2016 and 2016 to 2017 and movement to more and less generous insurance plans was examined using enrollment and insurance claims data from two U.S. Federally-facilitated Marketplace insurance carriers operating in the state of New Mexico for 2015 through 2017. Insurance plans are assigned to metal levels based on estimated plan actuarial value: Bronze (60%), Silver (70%), and Gold (80%). Odds ratios (ORs) and 95% confidence intervals (OR CI) were estimated using logistic regressions for subscribers with base year healthcare utilization. ORs were estimated for 1) reenrollment in the year following the base year, and 2) movement to a higher or lower actuarial value plan. Results: Approximately 50% of subscribers reenrolled with the same carrier for 2016 and 60% for 2017. Being enrolled 12 months was the strongest predictor for second year reenrollment. Older individuals were more likely to reenroll. Reenrollment was lower for the insurance carrier with higher second year premium changes. Chronic condition utilization characteristics were positively associated with reenrollment. Approximately 12% of Bronze subscribers moved to Silver or Gold, and had higher utilization after reenrollment. Among Silver subscribers, 6% moved to Gold and 6% to Bronze. Approximately 37% of Gold subscribers moved to Silver or Bronze. Discussion: Reenrollment was similar to published non-group insurance rates. Adverse selection and aging in place were observed. Evidence was weak for adverse retention. Some coverage change choices were rational, while others suggest subscribers may have difficulty making insurance choice decisions.
Laboratory Reports on Radiocarbon Age Determination. Peel Island, SE QLD, AUS (2008)
Creators: name: Hogg, Alan
name: Ross, A. C.
Publisher: name: Zenodo
Year: 2008
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database
Lab report
Peel Island

description: Original Radiocarbon Dating Lab reports for samples Wk-8009, Wk-8010, Wk-8011, Wk-8012, Wk-8013, Wk-8014 Sample batch originates from Peel Island, SE QLD, AUS The University of Waikato, Radiocarbon Dating Laboratory