cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Treatment outcomes among adults with HIV/non-communicable disease multimorbidity attending integrated care clubs in Cape Town, South Africa
Creators: name: Gausi, Blessings
name: Berkowitz, Natacha
name: Jacob, Nisha
name: Oni, Tolu
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Research
Treatment outcomes and paving the way for an HIV cure in Low and Middle Income Countries
HIV/AIDS
Hypertension
Diabetes mellitus
Non-communicable diseases
Multimorbidity
Integrated care
Adherence clubs
South Africa

description: Funder: Wellcome Trust; doi: http://dx.doi.org/10.13039/100004440
description: Abstract: Background: The growing burden of the HIV and non-communicable disease (NCD) syndemic in Sub- Saharan Africa has necessitated introduction of integrated models of care in order to leverage existing HIV care infrastructure for NCDs. However, there is paucity of literature on treatment outcomes for multimorbid patients attending integrated care. We describe 12-month treatment outcomes among multimorbid patients attending integrated antiretroviral treatment (ART) and NCD clubs in Cape Town, South Africa. Methods: As part of an integrated clubs (IC) model pilot implemented in 2016 by the local government at two primary health care clinics in Cape Town, we identified all multimorbid patients who were enrolled for IC for at least 12 months by August 2017. Mean adherence percentages (using proxy of medication collection and attendance of club visits) and optimal disease control (defined as the proportion of participants achieving optimal blood pressure, glycosylated haemoglobin control and HIV viral load suppression where appropriate) were calculated at 12 months before, at the point of IC enrolment and 12 months after IC enrolment. Predictors of NCD control 12 months post IC enrolment were investigated using multivariable logistic regression. Results: As of 31 August 2017, 247 HIV-infected patients in total had been enrolled into IC for at least 12 months. Of these, 221 (89.5%) had hypertension, 4 (1.6%) had diabetes mellitus and 22 (8.9%) had both diseases. Adherence was maintained before and after IC enrolment with mean adherence percentages of 92.2% and 94.2% respectively. HIV viral suppression rates were 98.6%, 99.5% and 99.4% at the three time points respectively. Retention in care was high with 6.9% lost to follow up at 12 months post IC enrolment. Across the 3 time-points, optimal blood pressure control was achieved in 43.1%, 58.9% and 49.4% of participants while optimal glycaemic control was achieved in 47.4%, 87.5% and 53.3% of participants with diabetes respectively. Multivariable logistic analyses showed no independent variables significantly associated with NCD control. Conclusion: Multimorbid adults living with HIV achieved high levels of HIV control in integrated HIV and NCD clubs. However, intensified interventions are needed to maintain NCD control in the long term.
D 7.10 Report on 3rd ADMAIORA workshop
Creators: name: Lorenzo Vannozzi
name: Andrea Cafarelli
name: Leonardo Ricotti
Publisher: name: Zenodo
Year: 2022

description: Deliverable describes the key dissemination and communication events organized in the third year of the ADMAIORA project, as devised in the preliminary dissemination, communication and exploitation plan. In particular, the second project-related scientific symposium was virtually held during the 47th European Society of Artificial Organs (ESAO) Congress by the Project Coordinator, which was postponed to 2021 due to the COVID-19 pandemic.
A technical Workshop was held in February 2021 by the Project Coordinator in collaboration with IOR, addressing clinical end-users, namely orthopedists, radiologists and other people interested in imaging and diagnostics. Here, the speakers discussed recent developments and potential future applications of diagnostic and therapeutic ultrasound for osteoarticular applications and beyond, highlighting the challenges yet to be addressed and the possible future impact of this technology, highlighting the links with the ADMAIORA project efforts. This workshop was already described in Deliverable D7.8.
A non-technical Workshop was held in October 2021, in which SSSA and IOR, in coordination with AMRER, an Italian association of rheumatic patients, promoted the project results to healthcare system actors, OA patients, and elderly people. The webinar was seen by approximately 2700 people.
Finally, this Deliverable describes the following additional key communication events:
- A TV interview delivered by Prof. Ricotti to “SuperQuark”, a program transmitted on RAI: Italian State Broadcaster, on ADMAIORA and the new frontiers of regenerative medicine (2.263.000 people reached), available also on YouTube (views: 11.800);
- A Promotional video produced by the Italian Olympic Committee (CONI) and shared during the Olympic games 2021 held in Tokyo, also promoted on the CONI social networks;
- A TEDx talk (Lungarno Mediceo) in September 2021, delivered by Prof. Ricotti, available also on YouTube (views: 1580).
Evaluating the CYP-IAPT transformation of child and adolescent mental health services in Cambridgeshire, UK: a qualitative implementation study
Creators: name: Burn, Anne-Marie
name: Vainre, Maris
name: Humphrey, Ayla
name: Howarth, Emma
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research
Child and adolescent mental health services
CYP-IAPT
Qualitative
Implementation
NPT
CFIR

description: Abstract: Background: The Children and Young People’s Improving Access to Psychological Therapies (CYP-IAPT) programme was introduced to transform Child and Adolescent Mental Health Services (CAMHS) across England. The programme comprised a set of principles that local CAMHS partnerships were expected to operationalise and embed with the aim of increasing access to services and improving the quality of care. This study explored how the implementation of the CYP-IAPT programme was executed and experienced by CAMHS professionals in the county of Cambridgeshire (UK), and the extent to which the CYP-IAPT principles were perceived to be successfully embedded into everyday practice. Methods: We analysed 275 documents relating to the CYP-IAPT programme issued between 2011 and 2015. We also conducted a thematic analysis of 20 qualitative interviews, undertaken at two time points, with professionals from three CAMHS teams in Cambridgeshire. Analysis was informed by implementation science frameworks. Results: Document analysis suggested that the CYP-IAPT programme was initially not clearly defined and lacked guidance on how to operationalise key programme principles and apply them in everyday practice. There was also a degree of programme evolution over time, which made it difficult for local stakeholders to understand the scope and aims of CYP-IAPT. Interviews with staff showed low coherent understanding of the programme, variable levels of investment among stakeholders and difficulties in collaborative working. Barriers and facilitators to programme implementation were identified at individual, service and strategic levels. These in turn impacted the local implementation efforts and sustainability of the programme in Cambridgeshire. Conclusions: We identified factors relating to programme design and national and local implementation planning, as well as features of inner and outer context, which impacted on the delivery and sustainability of the programme. These findings can be drawn upon to inform the development and delivery of other local and national quality improvement (QI) initiatives relating to children and young people’s mental health.
Kinematic constraints on the ages and kick velocities of Galactic neutron star binaries
Creators: name: Disberg, Paul
name: Gaspari, Nicola
name: Levan, Andrew J.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The systems creating binary neutron stars (BNSs) experience systemic kicks when one of the components goes supernova. The combined magnitude of these kicks is still a topic of debate, and has implications for the eventual location of the transient resulting from the merger of the binary. For example, the offsets of short-duration gamma-ray bursts (SGRBs) resulting from BNS mergers depend on the BNS kicks. We investigated Galactic BNSs, and traced their motion through the Galaxy. This enabled us to estimate their kinematic ages and construct a BNS kick distribution, based on their Galactic trajectories. We used the pulsar periods and their derivatives to estimate the characteristic spin-down ages of the binaries. Moreover, we used a Monte Carlo estimation of their present-day velocity vector in order to trace back their trajectory and estimate their kinematic ages. These trajectories, in turn, were used to determine the eccentricity of their Galactic orbit. Based on simulations of kicked objects in the Galactic potential, we investigated the relationship between this eccentricity and kick velocity, in order to constrain the kicks imparted to the binaries at birth. We find that the Galactic BNSs are likely older than $\sim40$ Myr, which means their current (scalar) galactocentric speeds are not representative of their initial kicks. However, we find a close relationship between the eccentricity of a Galactic trajectory and the experienced kick. Using this relation, we constrained the kicks of the Galactic BNSs, depending on the kind of isotropy assumed in estimating their velocity vectors. These kick velocities are well-described by a log-normal distribution peaking around $\sim40-50$ km/s, and coincide with the peculiar velocities of the binaries at their last disc crossing.
description: 22 pages, 15 figures, accepted for publication by A&A
Внутренняя оборона города как часть общей стратегии битвы за Ленинград
Creators: name: Белозеров Борис Петрович
Publisher: name: Наука. Общество. Оборона
Year: 2013
Subjects: ВОГ
КОМЕНДАТУРЫ
COMMANDANT
НКВД
РАБОЧИЕ БАТАЛЬОНЫ
NKVD LABOR BATTALIONS
FOG

description: В Битве за Ленинград исключительное значение имела внутренняя оборона города как система оборонительных и предупредительных мер по отражению воздушных десантов врага, которые во взаимодействии с сухопутными войсками, могли захватить город.
Курсанты - дзержинцы в боях за Ленинград (1941-й год)
Creators: name: Кузинец Исай Моисеевич
Publisher: name: Наука. Общество. Оборона
Year: 2013
Subjects: КУРСАНТЫ
STUDENTS
ОБОРОНА
DEFENSE
ВОЕННО-МОРСКОЕ УЧИЛИЩЕ
NAVAL ACADEMY
ЛЕНИНГРАД
LENINGRAD
БОИ
ФАШИСТЫ
ФРОНТ
РУБЕЖ
БРИГАДА
BRIGADE
БАТАЛЬОН
BATTALION
FIGHTING FASCISTS
FRONT LINE

description: В статье говорится об участии курсантов Высшего военно-морского инженерного училища имени Ф.Э. Дзержинского в боях на подступах к Ленинграду в первые месяцы Великой Отечественной войны 1941-1945 гг.
Hermitian unitary matrices with modular permutation symmetry
Creators: name: Turek, Ondrej
name: Cheon, Taksu
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 15B10, 15B57, 81Q35

description: We study Hermitian unitary matrices $\mathcal{S}\in\mathbb{C}^{n,n}$ with the following property: There exist $r\geq0$ and $t>0$ such that the entries of $\mathcal{S}$ satisfy $|\mathcal{S}_{jj}|=r$ and $|\mathcal{S}_{jk}|=t$ for all $j,k=1,\ldots,n$, $j\neq k$. We derive necessary conditions on the ratio $d:=r/t$ and show that these conditions are very restrictive except for the case when $n$ is even and the sum of the diagonal elements of $§$ is zero. Examples of families of matrices $\mathcal{S}$ are constructed for $d$ belonging to certain intervals. The case of real matrices $\mathcal{S}$ is examined in more detail. It is demonstrated that a real $\mathcal{S}$ can exist only for $d=\frac{n}{2}-1$, or for $n$ even and $\frac{n}{2}+d\equiv1\pmod 2$. We provide a detailed description of the structure of real $\mathcal{S}$ with $d\geq\frac{n}{4}-\frac{3}{2}$, and derive a sufficient and necessary condition of their existence in terms of the existence of certain symmetric $(v,k,λ)$-designs. We prove that there exist no real $\mathcal{S}$ with $d\in\left(\frac{n}{6}-1,\frac{n}{4}-\frac{3}{2}\right)$. A parametrization of Hermitian unitary matrices is also proposed, and its generalization to general unitary matrices is given. At the end of the paper, the role of the studied matrices in quantum mechanics on graphs is briefly explained.
description: revised version, 21 pages
Diurnal oscillations in gut bacterial load and composition eclipse seasonal and lifetime dynamics in wild meerkats
Creators: name: Risely, Alice
name: Wilhelm, Kerstin
name: Clutton-Brock, Tim
name: Manser, Marta B.
name: Sommer, Simone
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/631/158/855
/631/326/2565/855
/631/326/2565/2134
/49
/49/23
article

description: Abstract: Circadian rhythms in gut microbiota composition are crucial for metabolic function, yet the extent to which they govern microbial dynamics compared to seasonal and lifetime processes remains unknown. Here, we investigate gut bacterial dynamics in wild meerkats (Suricata suricatta) over a 20-year period to compare diurnal, seasonal, and lifetime processes in concert, applying ratios of absolute abundance. We found that diurnal oscillations in bacterial load and composition eclipsed seasonal and lifetime dynamics. Diurnal oscillations were characterised by a peak in Clostridium abundance at dawn, were associated with temperature-constrained foraging schedules, and did not decay with age. Some genera exhibited seasonal fluctuations, whilst others developed with age, although we found little support for microbial senescence in very old meerkats. Strong microbial circadian rhythms in this species may reflect the extreme daily temperature fluctuations typical of arid-zone climates. Our findings demonstrate that accounting for circadian rhythms is essential for future gut microbiome research.
MPEC 2023-X209 : 2023 XY7
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 XY7

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Additional file 2 of The α-mating factor secretion signals and endogenous signal peptides for recombinant protein secretion in Komagataella phaffii
Creators: name: Zou, Chenwei
name: Lu, Lingfang
name: Wang, Shengyan
name: Zhang, Chenshan
name: Chen, Xuequn
name: Lin, Yao
name: Huang, Yide
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 2: Fig. S1. The construction schematic of expression vectors with different α-MF secretion signal or endogenous signal peptide. The EGFP gene was cloned into pPIC9K between SnaB I and EcoR I sites. The pPIC9K-EGFP was digested with BamH I and SnaB I to remove the α-MF secretion signal of S. cerevisiae, and then an α-MF secretion signal from yeast specie or endogenous signal peptide was inserted to replace the α-MF signal leader of S. cerevisiae. Fig. S2. The structures of pro-peptides of α-MF secretion signals predicted by alphafold2 model. S.ce: S. cerevisiae; W.cl: W. ciferrii; K.na: K. naganishii; L.fe: L. fermentati; T.bl: T. blattae CBS 6284; T.ph: T. phaffii CBS 4417; K.sa: K. saulgeensis; N.ca2: N. castellii CBS 4309 (alpha 2); C.al: C. albicans P75063; S.bo: S. boulardii; N.ca1: N. castellii CBS 4309 (alpha 1); L.th: L. thermotolerans CBS 6340; N.da1: N. dairenensis CBS 421 (alpha 1); G.ca: G. candidum; N.cr: N. crass; L.me: L. meyersii CBS 8951; E.cy: E. cymbalariae; L.da: L. dasiensis CBS 10888; Y.li: Y. lipolytica CLIB122; M.fa: M. farinosa CBS 7064; L.sp: Lachancea sp. CBS 6924; S.ku1: S. kudriavzevii (alpha 1); L.qu: L. quebecensis; C.pa: C. parapsilosis; A.po: A. porosum; Z.me: Z. mellis; L.mi: L. mirantina; S.pa: S. paradoxus; L.no: L. nothofagi CBS 11611; S.ku2: S. kudriavzevii (alpha 1); Z.ro: Z. rouxii; M.pu: M. aff. pulcherrima; C.or: C. orthopsilosis Co 90-125; K.pa: K. pastoris; N.da2: N. dairenensis CBS 421 (alpha 2); S.st: S. stipitis CBS 6054; D.ha: D. hansenii CBS767; H.op: H. opuntiae.
Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist
Creators: name: Salas-Leiva, Dayana E.
name: Tromer, Eelco C.
name: Curtis, Bruce A.
name: Jerlström-Hultqvist, Jon
name: Kolisko, Martin
name: Yi, Zhenzhen
name: Salas-Leiva, Joan S.
name: Gallot-Lavallée, Lucie
name: Williams, Shelby K.
name: Kops, Geert J. P. L.
name: Archibald, John M.
name: Simpson, Alastair G. B.
name: Roger, Andrew J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/631/181
/631/326
/45/23
/49/91
article

description: Funder: Canadian Institutes of Health Research (Grant: FRN-142349) Natural Sciences and Engineering Research Council of Canada (Grant: RGPIN 05871-2014)
description: Abstract: Cells replicate and segregate their DNA with precision. Previous studies showed that these regulated cell-cycle processes were present in the last eukaryotic common ancestor and that their core molecular parts are conserved across eukaryotes. However, some metamonad parasites have secondarily lost components of the DNA processing and segregation apparatuses. To clarify the evolutionary history of these systems in these unusual eukaryotes, we generated a genome assembly for the free-living metamonad Carpediemonas membranifera and carried out a comparative genomics analysis. Here, we show that parasitic and free-living metamonads harbor an incomplete set of proteins for processing and segregating DNA. Unexpectedly, Carpediemonas species are further streamlined, lacking the origin recognition complex, Cdc6 and most structural kinetochore subunits. Carpediemonas species are thus the first known eukaryotes that appear to lack this suite of conserved complexes, suggesting that they likely rely on yet-to-be-discovered or alternative mechanisms to carry out these fundamental processes.
The Cosmic Linear Anisotropy Solving System (CLASS) IV: Efficient implementation of non-cold relics
Creators: name: Lesgourgues, Julien
name: Tram, Thomas
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a new flexible, fast and accurate way to implement massive neutrinos, warm dark matter and any other non-cold dark matter relics in Boltzmann codes. For whatever analytical or numerical form of the phase-space distribution function, the optimal sampling in momentum space compatible with a given level of accuracy is automatically found by comparing quadrature methods. The perturbation integration is made even faster by switching to an approximate viscous fluid description inside the Hubble radius, which differs from previous approximations discussed in the literature. When adding one massive neutrino to the minimal cosmological model, CLASS becomes just 1.5 times slower, instead of about 5 times in other codes (for fixed accuracy requirements). We illustrate the flexibility of our approach by considering a few examples of standard or non-standard neutrinos, as well as warm dark matter models.
description: 23 pages, 8 figures, 3 tables. Matches published version. Code available at http://class-code.net
Мозг военной организации государства: величие идей и свершений
Creators: name: Уткин Борис Павлович
Publisher: name: Наука. Общество. Оборона
Year: 2013
Subjects: РОССИЯ
RUSSIA
СОВЕТСКИЙ СОЮЗ
SOVIET UNION
ГЕНЕРАЛЬНЫЙ ШТАБ
GENERAL STAFF
ИСТОРИЯ
HISTORY
ВОЙНА
WAR
УПРАВЛЕНИЕ
CONTROL

description: Автором предложена и обоснована периодизация истории Генерального штаба России, особенности его функционирования на различных этапах развития, роль и место в обеспечении военной безопасности государства.
Additional file 1 of Prolonging the time of progesterone supplementation to improve the pregnancy outcomes of single day 6 blastocyst transfer in frozen-thawed cycles: study protocol for a randomized controlled trial
Creators: name: Xu, Manlin
name: Yan, Yuan
name: Shen, Xiaoyue
name: Sun, Haixiang
name: Yan, Guijun
name: Kong, Na
name: Jiang, Yue
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 1.
Towards renewable production of CO and H₂O₂ in flow electrolyzers
Creators: name: Fink, Arthur Guillaume
Publisher: name: University of British Columbia
Year: 2023

description: The manufacturing industry relies on fossil fuels as a source of heat, C, and H atoms. Electrochemical processes powered by renewable energy can reduce this dependence on fossil fuels if integrated properly to the existing industry. Two examples are investigated in this thesis: (i) CO₂ electro-conversion to CO directly from model carbon capture solutions in bicarbonate electrolyzers to bypass energy-intensive CO₂(g) regeneration otherwise required for gas-fed electrolyzers; and (ii) anthraquinone hydrogenation for H₂O₂ production in a membrane reactor that sources H atoms from water electrolysis instead of carbon-intensive steam methane reforming. This thesis first investigates the role of the counter alkali cation in bicarbonate electrolyzers. The selectivity for CO formation increased with the ionic radius of the cation to reach a maximum of ~80% during electrolysis of 3 M CsHCO₃ solutions at 100 mA cm⁻². The identity of the cation has no impact on in-situ generation of electrochemically active CO₂. These results demonstrate the importance of the identity of the cation to maximize activity towards CO₂ electro-reduction in bicarbonate electrolyzers. This thesis then investigates the inclusion of enzymatic carbon capture promoters to the feedstock solution of the bicarbonate electrolyzer. 16% CO selectivity was achieved in presence of the enzyme at 100 mA cm⁻². This result is 3-fold lower than without the enzyme due to enzyme chemisorption on the electrocatalyst. The addition of hydrophobic layers on the cathode prevents the enzyme from poisoning the electrocatalyst. This thesis demonstrates successful integration of enzymatic carbon capture to bicarbonate electrolysis. The last part of this thesis demonstrates the hydrogenation of anthraquinones in a membrane reactor using water and electricity instead of methane-derived H₂(g). Membrane reactors separate the electrochemical reduction of H⁺ into H atoms from the hydrogenation of anthraquinones by a H-permeable Pd membrane. This physical separation enabled a 3-fold increase in hydrogenation rates compared to the previous benchmark in the field of electrochemical-derived anthraquinone hydrogenation. This thesis demonstrates 48 h of stable production of H₂O₂ from anthraquinones hydrogenated in the membrane reactor. These results testify to the power of membrane reactors to decarbonize the manufacturing industry.
Участие офицеров Генерального штаба в военно-энциклопедической деятельности в XVIII - начале XX века
Creators: name: Юров Роман Валерианович
Publisher: name: Наука. Общество. Оборона
Year: 2013
Subjects: ГЕНЕРАЛЬНЫЙ ШТАБ
GENERAL STAFF
РОССИЯ
RUSSIA
ЭНЦИКЛОПЕДИЯ
ENCYCLOPEDIA
СЛОВАРЬ
DICTIONARY
ЛЕКСИКОН
КНИГА
ТЕРМИН
A TERM THE MILITARY
ВОЕННЫЙ
LEKSOKON BOOK

description: В статье показаны роль и место офицеров Генерального штаба в создании военно-энциклопедических трудов в XIX начала XX века.
Пример фронтовика Великой Отечественной войны - талантливого воспитателя воинов и патриотов России. К 90-летию со дня рождения Бориса Павловича Уткина
Creators: name: Тюшкевич Степан Андреевич
name: Кикнадзе Владимир Георгиевич
Publisher: name: Наука. Общество. Оборона
Year: 2013
Subjects: УТКИН
UTKIN
ГЕНЕРАЛ
GENERAL
ДЕЯТЕЛЬНОСТЬ
ACTIVITIES
ВЕЛИКАЯ ОТЕЧЕСТВЕННАЯ ВОЙНА
GREAT PATRIOTIC WAR
ПАТРИОТ
PATRIOT
ТРУД
ПОБЕДА
LABOR VICTORY

description: Статья о жизни и деятельности участника Великой Отечественной войны, боевого генерала, воспитателя, патриота, военного историка и энциклопедиста генерал-полковника Бориса Павловича Уткина, которому 23 февраля 2013 г. исполнилось 90 лет.
MPEC 2023-X210 : 2023 XA8
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 XA8

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
400 лет Уральска в историографии нового и новейшего времени
Creators: name: Соклаков Александр Юрьевич
Publisher: name: Наука. Общество. Оборона
Year: 2013
Subjects: ИСТОРИОГРАФИЯ
HISTORIOGRAPHY
ЖАЙЫК
УРАЛЬСК
URALSK
ЯИЦК
ЗАПАДНЫЙ КАЗАХСТАН
WEST KAZAKHSTAN
ДЕНЬ ГОРОДА
УРАЛЬСКИЕ КАЗАКИ
ЮБИЛЕЙ ГОРОДА
URAL COSSACKS CITY'S ANNIVERSARY OF THE CITY
М.Н. СДЫКОВ
MN SDYKOV
Н.Г. ЧЕСНОКОВ
NG CHESNOKOV
ИСТОРИЯ РОССИИ
RUSSIAN HISTORY
ИСТОРИЯ КАЗАХСТАНА
HISTORY OF KAZAKHSTAN
ИСТОРИЯ КАЗАЧЕСТВА
HISTORY OF THE COSSACKS
400-ЛЕТИЕ УРАЛЬСКА
THE 400TH ANNIVERSARY OF URALSK
ZHAIYK
YAITSKY

description: Рассматривая историографию города Уральска, автор призывает к взвешенности суждений при оценке времени основания города в 1613 году.
A-Priori Validation of Scalar Dissipation Rate Models for Turbulent Non-Premixed Flames
Creators: name: Sitte, M. P.
name: Turquand D’Auzay, C.
name: Giusti, A.
name: Mastorakos, E.
name: Chakraborty, N.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
Scalar dissipation rate
Large-eddy simulation
Conditional moment closure
Non-premixed flames

description: Funder: Engineering and Physical Sciences Research Council; doi: http://dx.doi.org/10.13039/501100000266
description: Funder: University of Cambridge
description: Abstract: The modelling of scalar dissipation rate in conditional methods for large-eddy simulations is investigated based on a priori direct numerical simulation analysis using a dataset representing an igniting non-premixed planar jet flame. The main objective is to provide a comprehensive assessment of models typically used for large-eddy simulations of non-premixed turbulent flames with the Conditional Moment Closure combustion model. The linear relaxation model gives a good estimate of the Favre-filtered scalar dissipation rate throughout the ignition with a value of the related constant close to the one deduced from theoretical arguments. Such value of the constant is one order of magnitude higher than typical values used in Reynolds-averaged approaches. The amplitude mapping closure model provides a satisfactory estimate of the conditionally filtered scalar dissipation rate even in flows characterised by shear driven turbulence and strong density variation.
"в борьбе за историческую Россию. . . ". Издание Русского охранного Корпуса "Наши Вести"
Creators: name: Белков Алексей Николаевич
Publisher: name: Наука. Общество. Оборона
Year: 2013
Subjects: ИСТОРИЯ
HISTORY
КОЛЛАБОРАЦИОНИЗМ
COLLABORATIONISM
А.А. ВЛАСОВ
РУССКИЙ ОХРАННЫЙ КОРПУС
RUSSIAN PROTECTIVE CORPS
"НАШИ ВЕСТИ"
"OUR NEWS"
ПОЛКОВНИК А.И. РОГОЖИН
COLONEL A.I. ROGOZHIN
С.В. ВОЛКОВ
A.A.VLASOV
S.V. VOLKOV

description: В статье показана история журнала Союза бывших чинов Русского охранного копуса «Наши Вести» от зарождения в лагере для военнопленных до прекращения выхода в 2001 году.
The factors that influence protostellar multiplicity I: Gas temperature, density, and mass in Perseus with Nobeyama
Creators: name: Murillo, N. M.
name: Fuchs, C. M.
name: Harsono, D.
name: Sakai, N.
name: Hacar, A.
name: Johnstone, D.
name: Mignon-Risse, R.
name: Zeng, S.
name: Hsieh, T. -H.
name: Yang, Y. -L.
name: Tobin, J. J.
name: Persson, M. V.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Protostellar multiplicity is common at all stages and mass ranges. However, the factors that determine the multiplicity of protostellar systems have not been systematically characterized through their molecular gas. Nobeyama 45m Radio Observatory OTF maps of HCN, HNC, HCO$^+$, and N$_2$H$^+$ (J = 1--0) toward five subregions in Perseus, complemented with single pointing APEX observations of HNC (J = 4--3) are used to derive physical parameters of the dense gas. Both observations have angular resolutions of $\sim$18", equivalent to $\sim$5000 AU scales at the distance of Perseus. Kinetic gas temperature is derived from the $I$(HCN)/$I$(HNC) J = 1--0 ratio, and H$_2$ density is obtained from the HNC J=4--3/J=1--0 ratio. These parameters are used to obtain the N$_2$H$^+$ and HCO$^+$ gas masses. The inferred and derived parameters are compared to source parameters. Inferred mean kinetic gas temperature ($I$(HCN)/$I$(HNC) J=1--0 ratio; ranging between 15 and 26 K), and H$_2$ volumetric density (HNC J=4--3/J=1--0; 10$^5$ -- 10$^6$ cm$^{-3}$) do not show correlations with multiplicity in Perseus. The derived gas and dust masses, 1.3 to 16 $\times~10^{-9}$ M$_{\odot}$ for the N$_2$H$^+$ gas mass, 0.1 to 25 M$_{\odot}$ for envelope dust masses (850 $μ$m), and 0.8 to 10 $\times~10^{-10}$ M$_{\odot}$ for the HCO$^+$ gas mass, are correlated to multiplicity and number of protostellar components. The warm gas masses are a factor of 16 lower than the cold gas masses. This work shows that gas and dust mass is correlated to multiplicity at $\sim$5000 AU scales in Perseus. Higher order multiples tend to have higher gas and dust masses in general, while close binaries (separations $\leq$7") and single protostars have similar gas and dust mass distributions. On the other hand, H$_2$ density and kinetic gas temperature do not show any correlation with multiplicity.
description: 25 pages, 12 figures, 3 appendices. Accepted for publication in A&A. The abstract has been modified to comply with arXiv's character limit
A mutant wfs1 zebrafish model of Wolfram syndrome manifesting visual dysfunction and developmental delay
Creators: name: Cairns, G.
name: Burté, F.
name: Price, R.
name: O’Connor, E.
name: Toms, M.
name: Mishra, R.
name: Moosajee, M.
name: Pyle, A.
name: Sayer, J. A.
name: Yu-Wai-Man, P.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/631/208
/692/699/3161
article

description: Funder: Fight for Sight UK; doi: http://dx.doi.org/10.13039/501100000615
description: Funder: Wellcome Trust; doi: http://dx.doi.org/10.13039/100004440
description: Abstract: Wolfram syndrome (WS) is an ultra-rare progressive neurodegenerative disorder defined by early-onset diabetes mellitus and optic atrophy. The majority of patients harbour recessive mutations in the WFS1 gene, which encodes for Wolframin, a transmembrane endoplasmic reticulum protein. There is limited availability of human ocular and brain tissues, and there are few animal models for WS that replicate the neuropathology and clinical phenotype seen in this disorder. We, therefore, characterised two wfs1 zebrafish knockout models harbouring nonsense wfs1a and wfs1b mutations. Both homozygous mutant wfs1a−/− and wfs1b−/− embryos showed significant morphological abnormalities in early development. The wfs1b−/− zebrafish exhibited a more pronounced neurodegenerative phenotype with delayed neuronal development, progressive loss of retinal ganglion cells and clear evidence of visual dysfunction on functional testing. At 12 months of age, wfs1b−/− zebrafish had a significantly lower RGC density per 100 μm2 (mean ± standard deviation; 19 ± 1.7) compared with wild-type (WT) zebrafish (25 ± 2.3, p < 0.001). The optokinetic response for wfs1b−/− zebrafish was significantly reduced at 8 and 16 rpm testing speeds at both 4 and 12 months of age compared with WT zebrafish. An upregulation of the unfolded protein response was observed in mutant zebrafish indicative of increased endoplasmic reticulum stress. Mutant wfs1b−/− zebrafish exhibit some of the key features seen in patients with WS, providing a versatile and cost-effective in vivo model that can be used to further investigate the underlying pathophysiology of WS and potential therapeutic interventions.
Characterization of a novel family of repressors affecting many processes during Arabidopsis thaliana seed development
Creators: name: Hoy, Ryan
Publisher: name: University of British Columbia
Year: 2024

description: The seed is a vital component of the plant life cycle and an innovative strategy that plants use to reproduce and survive through extended periods of adverse environmental conditions. The processes involved in the development of the seed are highly complex, and one novel clade of genes that was identified to play a role in controlling the genetic network of seed development is the DYNAMIC INFLUENCER OF GENE EXPRESSION (DIG) clade. Using genetic strategies including Yeast 2 Hybrid and a mutagenesis screen, I worked to elucidate the mechanisms behind the DIG clade’s regulation of this genetic network. My proposed model shows that through protein-protein interactions, transcription factors can recruit DIG proteins to target genes, and in turn DIGs interact with VP1/ABI3-LIKE 2 (VAL2) which recruits the Polycomb Repressive Complexes 1 and 2 to regulate the target genes expression through chromatin modifications.
Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity
Creators: name: Panagiotou, Stavros
name: Chaguza, Chrispin
name: Yahya, Reham
name: Audshasai, Teerawit
name: Baltazar, Murielle
name: Ressel, Lorenzo
name: Khandaker, Shadia
name: Alsahag, Mansoor
name: Mitchell, Tim J.
name: Prudhomme, Marc
name: Kadioglu, Aras
name: Yang, Marie
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/692/699
/692/699/255
/692/699/255/1318
article

description: Funder: Joint Programming Initiative on Antimicrobial Resistance; doi: http://dx.doi.org/10.13039/100013281
description: Funder: UK Medical Research Council
description: Abstract: Streptococcus pneumoniae is a devastating global pathogen. Prevalent in sub-Saharan Africa, pneumococcal serotype 1 is atypical in that it is rarely found as a nasopharyngeal coloniser, yet is described as one of the most common causes of invasive pneumococcal disease. Clonal sequence type (ST)-306 and ST615 are representative of the two major serotype 1 lineages A and C, respectively. Here we investigated the virulence properties and haemolytic activities of these 2 clonal types using in vivo mouse models and in vitro assays. A lethal dose of ST615 administered intranasally to mice led to the rapid onset of disease symptoms and resulted in 90% mortality. In contrast, mice exposed to the same infection dose of ST306 or a pneumolysin (Ply)-deficient ST615 failed to develop any disease symptoms. Interestingly, the 2 strains did not differ in their ability to bind the immune complement or to undergo neutrophil-mediated phagocytosis. Upon comparative genomic analysis, we found higher within-ST sequence diversity in ST615 compared with ST306 and determined that ZmpA, ZmpD proteins, and IgA protease, were uniquely found in ST615. Using cell fractionation and cell contact-dependent assay, we made the unexpected finding that ST615 harbours the expression of two haemolytic variants of Ply: a cell-wall restricted fully haemolytic Ply, and a cytosolic pool of Ply void of any detectable haemolytic activity. This is the first time such a phenomenon has been described. We discuss the biological significance of our observation in relation to the aptitude of the pneumococcus for sustaining its human reservoir.
Interpolating the Sherrington-Kirkpatrick replica trick
Creators: name: Barra, Adriano
name: Guerra, Francesco
name: Mingione, Emanuele
Publisher: name: arXiv
Year: 2011
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The interpolation techniques have become, in the past decades, a powerful approach to lighten several properties of spin glasses within a simple mathematical framework. Intrinsically, for their construction, these schemes were naturally implemented into the cavity field technique, or its variants as the stochastic stability or the random overlap structures. However the first and most famous approach to mean field statistical mechanics with quenched disorder is the replica trick. Among the models where these methods have been used (namely, dealing with frustration and complexity), probably the best known is the Sherrington-Kirkpatrick spin glass: In this paper we are pleased to apply the interpolation scheme to the replica trick framework and test it directly to the cited paradigmatic model: interestingly this allows to obtain easily the replica-symmetric control and, synergically with the broken replica bounds, a description of the full RSB scenario, both coupled with several minor theorems. Furthermore, by treating the amount of replicas $n\in(0,1]$ as an interpolating parameter (far from its original interpretation) this can be though of as a quenching temperature close to the one introduce in off-equilibrium approaches and, within this viewpoint, the proof of the attended commutativity of the zero replica and the infinite volume limits can be obtained.
description: This article is dedicated to David Sherrington on the occasion of his seventieth birthday
Effet du climat sur la résistance des enrobés recyclés
Creators: name: Bordjiba, Abdelhak
name: Guenfoud, Hamza
Publisher: name: Academic Journal of Civil Engineering
Year: 2019

description: Tout au long de sa vie, une chaussée est exposée à des conditions climatiques différentes et variées, le plus souvent sans aucune protection. C’est à la température, dans le comportement de la chaussée, que revient le rôle prépondérant, et ce particulièrement pour les chaussées souples. L’enrobé bitumineux est composé de granulats et de bitume. Bien que le pourcentage massique du bitume dans l’enrobé soit de l’ordre de 4 à 7 % seulement, le comportement de l’enrobé à plusieurs niveaux est régi par celui du bitume. Ce dernier, de par son comportement viscoélastique, confère un caractère thermo-susceptible à l’enrobé. La rigidité de l’enrobé diminue donc avec l’augmentation de sa température. Le module de rigidité est aussi impacté par la vitesse de sollicitation et diminue lorsque la vitesse de sollicitation diminue. Cette étude traite l’effet du climat sur la résistance à l’orniérage des enrobés recyclés.
description: Academic Journal of Civil Engineering, Vol 36 No 1 (2018): Special Issue - RUGC 2018 St Etienne
Genetic diversity of Salmonella Paratyphi A isolated from enteric fever patients in Bangladesh from 2008 to 2018
Creators: name: Rahman, Sadia Isfat Ara
name: Nguyen, To Nguyen Thi
name: Khanam, Farhana
name: Thomson, Nicholas R.
name: Dyson, Zoe A.
name: Taylor-Brown, Alyce
name: Chowdhury, Emran Kabir
name: Dougan, Gordon
name: Baker, Stephen
name: Qadri, Firdausi
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: subject: Research Article
subject: Medicine and health sciences
subject: Biology and life sciences
subject: People and places
subject: Computer and information sciences
subject: FOS: Computer and information sciences

description: Funder: International Centre for Diarrhoeal Disease Research
description: Funder: NIHR BRC
description: Background: The proportion of enteric fever cases caused by Salmonella Paratyphi A is increasing and may increase further as we begin to introduce typhoid conjugate vaccines (TCVs). While numerous epidemiological and genomic studies have been conducted for S. Typhi, there are limited data describing the genomic epidemiology of S. Paratyphi A in especially in endemic settings, such as Bangladesh. Principal findings: We conducted whole genome sequencing (WGS) of 67 S. Paratyphi A isolated between 2008 and 2018 from eight enteric disease surveillance sites across Bangladesh. We performed a detailed phylogenetic analysis of these sequence data incorporating sequences from 242 previously sequenced S. Paratyphi A isolates from a global collection and provided evidence of lineage migration from neighboring countries in South Asia. The data revealed that the majority of the Bangladeshi S. Paratyphi A isolates belonged to the dominant global lineage A (67.2%), while the remainder were either lineage C (19.4%) or F (13.4%). The population structure was relatively homogenous across the country as we did not find any significant lineage distributions between study sites inside or outside Dhaka. Our genomic data showed presence of single point mutations in gyrA gene either at codon 83 or 87 associated with decreased fluoroquinolone susceptibility in all Bangladeshi S. Paratyphi A isolates. Notably, we identified the pHCM2- like cryptic plasmid which was highly similar to S. Typhi plasmids circulating in Bangladesh and has not been previously identified in S. Paratyphi A organisms. Significance: This study demonstrates the utility of WGS to monitor the ongoing evolution of this emerging enteric pathogen. Novel insights into the genetic structure of S. Paratyphi A will aid the understanding of both regional and global circulation patterns of this emerging pathogen and provide a framework for future genomic surveillance studies.
Evaluation de champs de résistivité électrique de matériaux hygroscopiques : vers le monitoring et le diagnostic hydrique des structures
Creators: name: Hafsa, W.
name: Pham, M.D.
name: Angellier, N.
name: Takarli, M.
name: Ulmet, L.
name: Pop, O.
name: Nguyen, T.A.
name: Dubois, F.
Publisher: name: Academic Journal of Civil Engineering
Year: 2019

description: Le laboratoire GC2D-Egletons développe un dispositif expérimental s'appuyant sur des mesures résistives pour déterminer la répartition spatiale du taux d’humidité de matériaux hygroscopiques. Les expérimentations menées participent aussi au développement des outils de modélisation de la diffusion dans ces matériaux.
description: Academic Journal of Civil Engineering, Vol 36 No 1 (2018): Special Issue - RUGC 2018 St Etienne
Language, Gender, and Work: Investigating Women’s Employment Outcomes in Ottawa-Gatineau’s Federal Public Service
Creators: name: Bazinet, Renée
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2021
Subjects: women
gender
language
bilingualism
Francophone
Anglophone
Employment income
Occupational outcomes
Ottawa-Gatineau
Canada
Federal public service
labour

description: Women and men experience work differently owing to the gendered nature of work and workplaces, but there is limited insight into whether language and gender intersect to shape employment outcomes. This thesis project examines full-time employment in Ottawa-Gatineau to determine whether being French, English, or bilingual meaningfully influences employment status in the federal public service in terms of occupational attainment and employment income. A series of descriptive and inferential statistical analyses using the 2016 Canadian census are used to examine whether commuting patterns, occupational attainment, and annual employment income are significantly different across industrial sectors and between women and men, as well as between official language communities. The analysis reveals important differences in residential distribution between Anglophones and Francophones working in the federal public service as well as differences in commuting times, especially to suburban office locations. There are also important differences in occupational attainment and income attainment between women and men across official language communities, with women, especially francophone women, being more likely to occupy relatively low-pay administrative jobs in the federal public service compared to men or anglophone and bilingual women. In many ways, bilingualism in the federal public service is made real by the work of francophone women, although they are concentrated in some of the least-well paid occupations and stand to have ever more time consuming commutes as jobs are moved to suburban locations in Ottawa.
On topological properties of families of finite sets
Creators: name: Piña, Claribet
name: Uzcátegui, Carlos
Publisher: name: arXiv
Year: 2011
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: Primary 03E02, Secondary 05D10

description: We present results about the Cantor-Bendixson index of some subspaces of a uniform family F of finite subsets of natural numbers with respect to the lexicographic order topology. As a corollary of our results we get that for any omega-uniform family F the restriction F|M is homeomorphic to F iff M contains intervals of arbitrary length of consecutive integers. We show the connection of these results with a topological partition problem of uniform families.
Exploring Photocatalytic and Electrocatalytic Reduction of CO2 with Re(I) and Zn(II) Complexes and Attempts to Employ a Novel Carbene Ligand to this Endeavor
Creators: name: Berro, Patrick
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2021
Subjects: Photocatalysis
Electrocatalysis
Transition Metal Complex
NHC

description: With the blend of addressing issues of sustainable energy with the environmental worries regarding emission of greenhouse gases, there is a motivation to target the efficient chemical reduction of CO2. Re(I) integrated photosensitizers and catalysts, synthesized from commercially available ligands, are introduced with the selective CO2 reduction of formic acid, making for a unique class of Re(I) catalysts typically selective for CO as a reduction product. Furthermore, synthesized Zn(II) phosphino aminopyridine complexes are structurally and computationally characterized as well as observed to function as unprecedented electrocatalysts for the reduction of CO2 to formic acid and CO. Lastly, with the importance and popularity of N-heterocyclic carbenes (NHCs) as a class of ligands in the field of organometallic catalysis, six-membered perimidine based carbenes are further explored. Synthesis of a chelating pyridyl-perimidine NHC in addition to potential transition metal catalysts are also attempted.
Synchronization of Kuramoto Oscillators on Knots
Creators: name: Sparavigna, Amelia Carolina
Publisher: name: arXiv
Year: 2011
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: A knot is a circle embedded in the space. Projecting a knot on a plane, we obtain a diagram which is known as the knot diagram. The vertices of the diagram, where the curved lines are crossed, can be considered as sites occupied by oscillators. The synchronization of these oscillators can be studied by means of a Kuramoto model. Here we propose to define some order parameters, of the complete knot diagram and of its regions, to study the synchronization of the system with regard to the different parts of it.
description: Knots, Knot diagrams, Kuramoto model, (revised title)