cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Image-Based Non-Contact Conductivity Prediction for Inkjet Printed Electrodes and Follow-Up Work of Toner Usage Prediction for Laser Electro-Phorographic Printers
Creators: name: Yan, Yang
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Electrical engineering not elsewhere classified

description: This thesis includes two parts. The main part is on the topic of conductivity prediction for Inkjet printed silver electrodes. The second part is about the follow-up work of toner usage prediction of laser electro-photographic printers.
For conductivity prediction of Inkjet printed silver electrodes part, the brief introduction is described below. Recently, electronic devices made with Inkjet printing technique and flexible thin fi lms have attracted great attention due to their potential applications in sensor manufacturing. This imaging system has become a great tool to monitor the quality of Inkjet printed electrodes due to the fact that most thickness or resistance measuring devices can destroy the surface of a printed electrode or even whole electrode. Thus, a non-contact image-based approach to estimate sheet resistance of Inkjet printed electrodes is developed.
The approach has two stages. Firstly, strip-shaped electrodes are systematically printed with various printing parameters. The sheet resistance measurement data aswell as images of the electrodes are acquired. Then, based on the real experimental data, the fi tting model is constructed and further used in predicting the sheetresistance of the Inkjet printed silver electrodes.
For toner usage prediction part, the introduction is described below. With the widespread use of laser electro-photographic printers in both industry and households fields, estimation of toner usage has great signi ficance to ensuring the full utilization of each cartridge. The follow-up work is focused on testing and improving feasibility, reliability, and adaptability of the Black Box Model (BBM) based two-stage strategy in estimating the toner usage. Comparing with previous methods, the training process for the firrst stage requires less time and disk storage, all while maintaining high accuracy. For the second stage, experiments are performed on various models of printers, with cyan(C), magenta(M), yellow(Y), and black(K) color cartridges.
Effectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis
Creators: name: Falkenhorst, Gerhard
name: Remschmidt, Cornelius
name: Harder, Thomas
name: Hummers-Pradier, Eva
name: Wichmann, Ole
name: Bogdan, Christian
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: Background: Routine vaccination of elderly people against pneumococcal diseases is recommended in many countries. National guidelines differ, recommending either the 23-valent polysaccharide vaccine (PPV23), the 13-valent conjugate vaccine (PCV13) or both. Considering the ongoing debate on the effectiveness of PPV23, we performed a systematic literature review and meta-analysis of the vaccine efficacy/effectiveness (VE) of PPV23 against invasive pneumococcal disease (IPD) and pneumococcal pneumonia in adults aged ≥60 years living in industrialized countries. Methods: We searched for pertinent clinical trials and observational studies in databases MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews. We assessed the risk of bias of individual studies using the Cochrane Risk of Bias tool for randomized controlled trials and the Newcastle-Ottawa Scale for observational studies. We rated the overall quality of the evidence by GRADE criteria. We performed meta-analyses of studies grouped by outcome and study design using random-effects models. We applied a sensitivity analysis excluding studies with high risk of bias. Results: We identified 17 eligible studies. Pooled VE against IPD (by any serotype) was 73% (95%CI: 10–92%) in four clinical trials, 45% (95%CI: 15–65%) in three cohort studies, and 59% (95%CI: 35–74%) in three case-control studies. After excluding studies with high risk of bias, pooled VE against pneumococcal pneumonia (by any serotype) was 64% (95%CI: 35–80%) in two clinical trials and 48% (95%CI: 25–63%) in two cohort studies. Higher VE estimates in trials (follow-up ~2.5 years) than in observational studies (follow-up ~5 years) may indicate waning protection. Unlike previous meta-analyses, we excluded two trials with high risk of bias regarding the outcome pneumococcal pneumonia, because diagnosis was based on serologic methods with insufficient specificity. Conclusions: Our meta-analysis revealed significant VE of PPV23 against both IPD and pneumococcal pneumonia by any serotype in the elderly, comparable to the efficacy of PCV13 against vaccine-serotype disease in a recent clinical trial in elderly people. Due to its broader serotype coverage and the decrease of PCV13 serotypes among adults resulting from routine infant immunization with PCV13, PPV23 continues to play an important role for protecting adults against IPD and pneumococcal pneumonia.
Asset Substitution Incentives and Uncertain Tax Choices
Creators: name: Godwin, Roger T
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Financial accounting
Taxation accounting
Finance

description: The equity holders of a firm typically control investment choices but enjoy limited liability, since the value of equity is the firm’s value in excess of the value of debt and other fixed claims. The asset substitution problem allows equity holders to expropriate value from other claimants by shifting downside risk from failed projects. To do so, equity holders substitute riskier investments for those with less risk. In the context of tax choices, firms pursue uncertain tax projects to reduce their current or future tax payments. Given the negative consequences of tax uncertainty documented by prior studies, understanding why firms pursue more uncertain tax projects is important for both internal and external stakeholders. In this study, I construct a model of the firm that highlights how asset substitution incentives influence the adoption of uncertain tax projects. I confirm the inferences from this model empirically to illustrate when firms are more likely to prefer more uncertain tax projects due to the investment distortion created by asset substitution incentives. Specifically, I find that firms in financial distress, firms with high growth potential, and loss firms adopt more uncertain tax projects than other firms. These results provide relevant insight for debt holders, regulators, and enforcement bodies.
Additional file 2 of Integrated transcriptomic and metabolomic analyses reveals anthocyanin biosynthesis in leaf coloration of quinoa (Chenopodium quinoa Willd.)
Creators: name: Zhang, Min
name: Li, Yueyou
name: Wang, Junling
name: Shang, Shaopu
name: Wang, Hongxia
name: Yang, Xinlei
name: Lu, Chuan
name: Wang, Mei
name: Sun, Xinbo
name: Liu, Xiaoqing
name: Wang, Xiaoxia
name: Wei, Boxiang
name: Lv, Wei
name: Mu, Guojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 2
Artificial intelligence in kidney transplantation: a 30-year bibliometric analysis of research trends, innovations, and future directions
Creators: name: He, Ying Jia
name: Liu, Pin Lin
name: Wei, Tao
name: Liu, Tao
name: Li, Yi Fei
name: Yang, Jing
name: Fan, Wen Xing
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Information Systems not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Hematology

description: Kidney transplantation is the definitive treatment for end-stage renal disease (ESRD), yet challenges persist in optimizing donor-recipient matching, postoperative care, and immunosuppressive strategies. This study employs bibliometric analysis to evaluate 890 publications from 1993 to 2023, using tools such as CiteSpace and VOSviewer, to identify global trends, research hotspots, and future opportunities in applying artificial intelligence (AI) to kidney transplantation. Our analysis highlights the United States as the leading contributor to the field, with significant outputs from Mayo Clinic and leading authors like Cheungpasitporn W. Key research themes include AI-driven advancements in donor matching, deep learning for post-transplant monitoring, and machine learning algorithms for personalized immunosuppressive therapies. The findings underscore a rapid expansion in AI applications since 2017, with emerging trends in personalized medicine, multimodal data fusion, and telehealth. This bibliometric review provides a comprehensive resource for researchers and clinicians, offering insights into the evolution of AI in kidney transplantation and guiding future studies toward transformative applications in transplantation science.
Implementation of the WHO multimodal Hand Hygiene Improvement Strategy in a University Hospital in Central Ethiopia
Creators: name: Pfäfflin, Frieder
name: Tufa, Tafese Beyene
name: Getachew, Million
name: Nigussie, Tsehaynesh
name: Schönfeld, Andreas
name: Häussinger, Dieter
name: Feldt, Torsten
name: Schmidt, Nicole
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: World Health Organization
subject: Hand hygiene
subject: Infection control
subject: Ethiopia
subject: Health-care worker
subject: Alcohol-based handrub
subject: 610 Medizin

description: Background: The burden of health-care associated infections in low-income countries is high. Adequate hand hygiene is considered the most effective measure to reduce the transmission of nosocomial pathogens. We aimed to assess compliance with hand hygiene and perception and knowledge about hand hygiene before and after the implementation of a multimodal hand hygiene campaign designed by the World Health Organization. Methods: The study was carried out at Asella Teaching Hospital, a university hospital and referral centre for a population of about 3.5 million in Arsi Zone, Central Ethiopia. Compliance with hand hygiene during routine patient care was measured by direct observation before and starting from six weeks after the intervention, which consisted of a four day workshop accompanied by training sessions and the provision of locally produced alcohol-based handrub and posters emphasizing the importance of hand hygiene. A second follow up was conducted three months after handing over project responsibility to the Ethiopian partners. Health-care workers’ perception and knowledge about hand hygiene were assessed before and after the intervention. Results: At baseline, first, and second follow up we observed a total of 2888, 2865, and 2244 hand hygiene opportunities, respectively. Compliance with hand hygiene was 1.4% at baseline and increased to 11.7% and 13.1% in the first and second follow up, respectively (p
sj-docx-2-sph-10.1177_19417381211029953 – Supplemental material for Diagnostic Accuracy of Clinical Tests Assessing Ligamentous Injury of the Talocrural and Subtalar Joints: A Systematic Review With Meta-Analysis
Creators: name: Netterström-Wedin, Fredh
name: Matthews, Mark
name: Bleakley, Chris
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine

description: Supplemental material, sj-docx-2-sph-10.1177_19417381211029953 for Diagnostic Accuracy of Clinical Tests Assessing Ligamentous Injury of the Talocrural and Subtalar Joints: A Systematic Review With Meta-Analysis by Fredh Netterström-Wedin, Mark Matthews and Chris Bleakley in Sports Health: A Multidisciplinary Approach
Longitudinal assessment of immunogenicity of inactivated COVID-19 booster immunization and breakthrough infection in blood donors: A multicenter study from 2021 to 2023
Creators: name: Yan, Ying
name: Halemubieke, Shana
name: Shan, Baifeng
name: Zhao, Lei
name: Duan, Youbin
name: Wang, Yifang
name: Wu, Mingrui
name: Bu, Xiaoxiao
name: Wang, Quaner
name: Chang, Le
name: Ji, Huimin
name: Sun, Huizhen
name: Liu, Yang
name: Sun, Peng
name: Liu, Ying
name: Wang, Lin
name: Li, Chuanbao
name: Zhang, Libo
name: Deng, Xuelian
name: Wang, Lunan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Assessing immune responses across diverse populations is essential for refining public health strategies. Blood donors offer valuable insights into community-level immunity. This study aims to investigate immune responses associated with inactivated COVID-19 booster immunization and breakthrough infections in blood donors. This study was conducted in a cohort of blood donors from six centers across five of China’s seven major geographical regions, spanning from December 2021 to February 2023. Blood samples were collected before booster vaccination, at 1, 3, and 6 months post-vaccination, as well as 1 month post-infection. SARS-CoV-2-specific antibodies, T cell specific IFNγ levels, and neutralizing antibodies against wild-type and Omicron strains were measured. Platelet count, anti-PF4 antibody, and D-dimer levels were assessed. Demographic characteristics were analyzed to determine their impact on immunogenicity. SARS-CoV-2-specific antibodies and IFNγ levels significantly increased post-booster, peaking one month after immunization. Antibodies continued to decrease at six months, while IFNγ levels remained stable at this point. Pseudovirus neutralization assays revealed elevated neutralizing antibodies following the booster dose, with minimal response to the XBB.1.5 variant. Following Omicron infection, antibody and IFNγ levels surpassed that observed post-booster. Participants aged 36–49 and those over 50 exhibited weaker immune responses post-booster than those ages 18–35, while those with BMI above 28 showed lower IFNγ levels. This study demonstrates the utility of blood donor samples for tracking immunization effectiveness against emerging pathogens, and highlights enhanced immune responses after booster immunization and breakthrough infections, underscoring the need for tailored vaccination strategies for different groups.
sj-docx-1-jop-10.1177_02698811211032445 – Supplemental material for Pharmacological treatment for Tourette syndrome in children and adults: What is the quality of the evidence? A systematic review
Creators: name: Besag, Frank MC
name: Vasey, Michael J
name: Lao, Kim SJ
name: Chowdhury, Uttom
name: Stern, Jeremy S
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)

description: Supplemental material, sj-docx-1-jop-10.1177_02698811211032445 for Pharmacological treatment for Tourette syndrome in children and adults: What is the quality of the evidence? A systematic review by Frank MC Besag, Michael J Vasey, Kim SJ Lao, Uttom Chowdhury and Jeremy S Stern in Journal of Psychopharmacology
Additional file 3 of Integrated transcriptomic and metabolomic analyses reveals anthocyanin biosynthesis in leaf coloration of quinoa (Chenopodium quinoa Willd.)
Creators: name: Zhang, Min
name: Li, Yueyou
name: Wang, Junling
name: Shang, Shaopu
name: Wang, Hongxia
name: Yang, Xinlei
name: Lu, Chuan
name: Wang, Mei
name: Sun, Xinbo
name: Liu, Xiaoqing
name: Wang, Xiaoxia
name: Wei, Boxiang
name: Lv, Wei
name: Mu, Guojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 3
Additional file 4 of Integrated transcriptomic and metabolomic analyses reveals anthocyanin biosynthesis in leaf coloration of quinoa (Chenopodium quinoa Willd.)
Creators: name: Zhang, Min
name: Li, Yueyou
name: Wang, Junling
name: Shang, Shaopu
name: Wang, Hongxia
name: Yang, Xinlei
name: Lu, Chuan
name: Wang, Mei
name: Sun, Xinbo
name: Liu, Xiaoqing
name: Wang, Xiaoxia
name: Wei, Boxiang
name: Lv, Wei
name: Mu, Guojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 4
ShapeUD: A Real-time, Modifiable, Tangible Interactive Tabletop System for Collaborative Urban Design
Creators: name: Tang, Hui
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Interaction and experience design
Urban design
Community planning
Human-computer interaction
Architectural design
Computer graphics
Decision support and group support systems

description: This research was to develop a real-time, modifiable, tangible interactive tabletop system for participatory urban design. The targeting user group was those stakeholders in urban design charrettes. Previous system solutions overlooked the importance of the modifiable tangible medium in the situation of reaching spatial-temporal consensus. These design issues impeded communication between the stakeholders and the professionals. Users of these systems had difficulties expressing ideas to professionals during the collaborative design process. Literature in evolving technology in the smart city context, collaborative urban design, embodied interaction, and depth-sensing was referred to guide the system design. Based on the review, this research identified the pivotal role of a shapeable and tangible medium in the system. The prototype system unified the modifiable, realistic model with its digital equivalent in urban analytics in real-time. By integrating tangible interaction, depth-sensing, and large touch screen tabletop, an intuitive, immersive decision-making interface for non-professional stakeholders could be created. During the system implementation, system elements centering ‘tangible interoperability’ were documented along the system pipeline. A heuristic evaluation, a method of usability inspection, was conducted to assess and to guide the future system design. The result was promising and inspiring. In the end, challenges and directions of system design were discussed. The contribution of this research included: discovering direction, centering tangibility, implementing a prototype, and documenting elements in each stage along the system pipeline of designing a modifiable tangible interactive tabletop system for the urban design charrette.
Metabolic phenotype of clinical and environmental Mycobacterium avium subsp. hominissuis isolates
Creators: name: Sanchini, Andrea
name: Dematheis, Flavia
name: Semmler, Torsten
name: Lewin, Astrid
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: 610 Medizin

description: Background: Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment, since it has been isolated from water, soil or dust. In recent years, knowledge on MAH at the molecular level has increased substantially. In contrast, knowledge of the MAH metabolic phenotypes remains limited. Methods: In this study, for the first time we analyzed the metabolic substrate utilization of ten MAH isolates, five from a clinical source and five from an environmental source. We used BIOLOG Phenotype MicroarrayTM technology for the analysis. This technology permits the rapid and global analysis of metabolic phenotypes. Results: The ten MAH isolates tested showed different metabolic patterns pointing to high intra-species diversity. Our MAH isolates preferred to use fatty acids such as Tween, caproic, butyric and propionic acid as a carbon source, and L-cysteine as a nitrogen source. Environmental MAH isolates resulted in being more metabolically active than clinical isolates, since the former metabolized more strongly butyric acid (p = 0.0209) and propionic acid (p = 0.00307). Discussion: Our study provides new insight into the metabolism of MAH. Understanding how bacteria utilize substrates during infection might help the developing of strategies to fight such infections.
Dihydromyricetin protects against cisplatin-induced renal injury and mitochondria-mediated apoptosis via the EGFR/HSP27/STAT3 signaling pathway
Creators: name: Xu, Zheming
name: Zhang, Minjing
name: Zhang, Xue
name: Han, Huirong
name: Ye, Weifeng
name: Chen, Zhenjie
name: Lv, Zhisu
name: Liu, Yang
name: Liu, Zhengye
name: Gong, Jianguang
name: Zhu, Bin
name: Zhou, Suhan
name: Zhu, Runzhi
name: Tao, Chang
name: Zhang, Gensheng
name: Yan, Xiang
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Cisplatin (CP) has been used as an effective chemotherapy drug for different types of cancers. Despite its therapeutic benefits, the clinical utility of CP is often hindered by adverse effects, notably acute kidney injury (AKI), which restricts its widespread application. Dihydromyricetin (DHM) is a flavonoid acquired from Ampelopsis grossedentata, exhibiting a range of pharmacological activities. The major objective of this research was to examine the possible molecular mechanism involved in CP-induced AKI and the protective function of DHM. In this study, the protective function of DHM against CP-induced AKI was assessed in both mice and HK-2 cells. Kidney dysfunction parameters and renal morphology were evaluated to ascertain the extent of protection. Additionally, proteomics techniques were employed to investigate the protective effect of DHM and elucidate the underlying molecular mechanisms involved in mitigating CP-induced AKI. In addition, protein levels of epidermal growth factor receptor (EGFR), p-EGFR, heat shock protein 27 (HSP27), p-HSP27, STAT3, and p-STAT3 in renal tissues were investigated. Furthermore, an EGFR-blocking agent (gefitinib) or si-RNA of HSP27 was used to study the effects of inhibiting EGFR or HSP27 on CP-induced renal injury. DHM decreased blood urea nitrogen (BUN) and creatinine in serum, alleviated renal morphological injury and downregulated the expression of CP-induced kidney injury molecule-1 and neutrophil gelatinase-related lipocalin. Proteomic data revealed HSP27 as a potential therapeutic target for AKI. DHM treatment resulted in the downregulation of EGFR, HSP27, and STAT3 phosphorylation, ultimately mitigating CP-induced AKI. In addition, the inhibition of EGFR or HSP27 reduced mitochondria-mediated apoptosis and CP-induced cell damage in HK-2 cells. DHM effectively inhibited CP-induced oxidative stress, inflammation, and mitochondria-mediated apoptosis through the EGFR/HSP27/STAT3 pathway.
MPEC 2025-F87 : 2025 FF3
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 FF3

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
The triglyceride-glucose index and acute kidney injury risk in critically ill patients with coronary artery disease
Creators: name: Zhang, Yi
name: Li, Gang
name: Li, Junjie
name: Jian, Bohao
name: Wang, Keke
name: Chen, Jiantao
name: Hou, Jian
name: Liao, Jianbo
name: Zhou, Zhuoming
name: Wu, Zhongkai
name: Liang, Mengya
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: The triglyceride-glucose (TyG) index, proven a reliable and simple surrogate of insulin resistance, has shown potential associations with cardiovascular outcomes and renal diseases. This research delved into the utility of the TyG index in predicting the risk of acute kidney injury (AKI) in patients with coronary artery disease (CAD), an area not extensively covered in existing literature. A cohort of patients with CAD was recruited from the Medical Information Mart for Intensive Care-IV database, and categorized into quartiles based on their TyG index. The primary outcome was AKI incidence, and the secondary outcome was renal replacement therapy (RRT). Scatterplot histograms, cox proportional hazards models, Kaplan-Meier survival curves, and restricted cubic splines were employed to investigate the association between the TyG index and the risk of AKI in patients with CAD. A total of 1,501 patients were enrolled in this study, predominantly male (61.56%), with a median age of 69.80 years. The AKI incidence was 67.22% among all patients, with the AKI stages increased with higher TyG levels (P for trend <0.001). The Kaplan-Meier survival analyses demonstrated statistically significant differences in AKI incidence and RRT application throughout the entire cohort, stratified by the TyG index quartiles (p < 0.001). Additionally, the restricted cubic spline analysis revealed a non-linear association between the TyG index and the risk of AKI (P for non-linear =0.637). Both multivariate Cox proportional hazards analyses (HR 1.62; 95% CI 1.15–2.27; p = 0.005) and multivariate logistic regression analyses (OR 2.16; 95% CI 1.18–3.94; p = 0.012) showed that the elevated TyG index was significantly related to AKI incidence. The association between TyG index and the risk of AKI is more significant in patients without diabetes (HR 1.27; 95% CI 1.14–1.42; p < 0.001), compared to patients with diabetes (P for interaction =0.013). In summary, the TyG index emerged as a reliable predictor for the occurrence of AKI in CAD patients during ICU stay. Furthermore, it is also anticipated to serve as a valuable indicator for non-diabetic patients in predicting the incidence of AKI.
Characteristics of participants in a randomized trial of an Internet intervention for depression (EVIDENT) in comparison to a national sample (DEGS1)
Creators: name: Späth, Christina
name: Hapke, Ulfert
name: Maske, Ulrike
name: Schröder, Johanna
name: Moritz, Steffen
name: Berger, Thomas
name: Meyer, Björn
name: Rose, Matthias
name: Nolte, Sandra
name: Klein, Jan Philipp
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: Depression
subject: Subclinical depression
subject: Randomized trial
subject: Intervention
subject: Population-based survey
subject: 610 Medizin

description: Background: While the efficacy of Internet interventions for depression has been demonstrated in numerous studies, there is concern that the participants in these studies may systematically differ from depressed subjects in the general population. The goal of this study was to compare participants in a large trial of an Internet intervention for depression with a population-based sample that reported depressive symptomatology in the same range of severity. Methodology: The analysis is based on a sample of participants of a randomized controlled trial testing the effectiveness of an Internet intervention for depression in mild to moderate depression (EVIDENT, N = 1013) and a subsample of participants in a representative population-based sample (DEGS1, n = 1978). The DEGS1 subsample was chosen based on the score in the Patient Health Questionnaire-9 (PHQ-9, score 5–14) as this was the main inclusion criterion for the EVIDENT study. Both samples were compared with respect to a range of demographic and clinical variables. Results: Compared with the DEGS1 subsample, participants in the EVIDENT sample were significantly more often female (68.6% vs. 56.3%), slightly older (mean age 42.9 vs. 40.4 years), had more often completed highest secondary education (51.3% vs. 22.4%), were clinically more severely affected (moderate depressive symptoms in 62.6% vs. 18.3%) and reported a lower quality of life. Conclusion: These findings indicate that participants in this Internet trial were not just internet savvy young males without significant impairment. Future studies should aim to recruit participants with lower educational status to increase the reach of Internet interventions.
Serán ceniza, mas tendrán sentido:  orígenes de las humanidades digitales en  España
Creators: name: Marcos Marin, Francisco
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Digital humanities
subject: Spain--Madrid
subject: Archives
subject: Machine translating
subject: Corpora (Linguistics)
subject: Computers
subject: Prosopography
subject: Digital images--Editing
subject: Editing
subject: Language and history

description: Se recogen en este capítulo los movimientos iniciales y proyectos de humani-dades digitales sobre la lengua española entre 1971 y 1993. Se trata, sobre todo, de proyectos españoles desarrollados principalmente en relación con universidades y centros de investigación de Madrid. Se hace referencia también a otros centros y otros proyectos, sobre todo cuando se iniciaron o desarrollaron en colaboración con esos centros madrileños. Lo que se intenta presentar es sobre todo un testi-monio prosopográfico, en línea con otros trabajos del autor (Marcos Marín, 2009, pp. 387-415), con la intención de ofrecer una imagen que pueda ser utilizada des-de el punto de vista histórico, como un retrato de un momento de la historia cultural de España y de la lengua española y del trabajo de grupo que ello supuso.
Akute schlaffe Myelitis bei Kindern im Jahr 2016 – Rückkehr von „Polio“?
Creators: name: Hübner, Johannes
name: Kruse, Bernd
name: Christen, Hans-Jürgen
name: Weidenmann, Jürgen
name: Weiner, Viktoria
name: Schöne-Backe, Jan-Christoph
name: Eichinger, Anna
name: Diedrich, Sabine
name: Müller-Felber, Wolfgang
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: 610 Medizin

description: Hintergrund: Obwohl die Poliomyelitis weltweit praktisch ausgerottet ist, treten in den letzten Jahren immer wieder Fälle einer polioartigen Erkrankung auf, die durch asymmetrische schlaffe Lähmungen unterschiedlichen Schweregrades gekennzeichnet sind. Methode: Erfasst wurden Kinder, die 2016 in klinischen Zentren in Bayern und in Niedersachsen betreut wurden. Deutschlandweite Häufigkeiten wurden über freiwillige Meldungen an das Robert Koch-Institut geschätzt. Für das gesamte Jahr 2016 wurden dort 16 Fälle registriert. Ergebnisse: In den beteiligten Zentren wurden im Sommer und Herbst 2016 insgesamt 7 Kinder mit akut aufgetretenen schlaffen Lähmungen betreut. Zwei exemplarische Fälle werden beschrieben, die einen milden und einen schweren Verlauf zusammenfassen. Zur raschen Diagnosefindung ist die Kombination aus klinisch-neurologischer Diagnostik sowie Neurophysiologie, Kernspintomographie und gezielter mikrobiologischer Diagnostik entscheidend. Charakteristisch sind kernspintomographisch nachweisbare Schädigungen des Vorderhorns im Rückenmark oder elektrophysiologisch nachweisbare Läsionen als Zeichen der Motoneuron-Schädigung. Ein Erreger ist aus dem Liquor praktisch nie nachweisbar, aber epidemiologische Zusammenhänge sowie der Nachweis von Viren aus Stuhl oder Atemwegssekreten weisen auf Enteroviren als Verursacher hin. Schlussfolgerung: Die Prognose der Erkrankung ist zu Beginn nicht einzuschätzen und gezielte therapeutische Maßnahmen stehen nicht zur Verfügung.
CNN-based Symbol Recognition and Detection in Piping Drawings
Creators: name: Zhang, Yuxi
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Civil engineering not elsewhere classified
CAD/CAM systems
Computer vision

description: Piping is an essential component in buildings, and its as-built information is critical to facility management tasks. Manually extracting piping information from legacy drawings that are in paper, PDF, or image format is mentally exerting, time-consuming, and error-prone. Symbol recognition and detection are core problems in the computer-based interpretation of piping drawings, and the main technical challenge is to determine robust features that are invariant to scaling, rotation, and translation. This thesis aims to use convolutional neural networks (CNNs) to automatically extract features from raw images, and consequently, to locate and recognize symbols in piping drawings. In this thesis, the Spatial Transformer Network (STN) is applied to improve the performance of a standard CNN model for recognizing piping symbols, and the Faster Region-based Convolutional Neural Network (Faster RCNN) is adopted to exploit its capacity in symbol detection. For experimentation, the synthetic data are generated as follows. Two datasets are generated for symbol recognition and detection, respectively. For recognition, eight types of symbols are synthesized based on the geometric constraints between the primitives. The drawing samples for detection are manually sketched using AutoCAD MEP software and its piping component library, and seven types of symbols are selected from the piping component library. Both sets of samples are augmented with various scales, rotations, and random noises. The experiment for symbol recognition is conducted and the accuracies of the recognition accuracy of the CNN + STN model and the standard CNN model are compared. It is observed that the spatial transformer layer improves the accuracy in classifying piping symbols from 95.39% to 98.26%. For the symbol detection task, the experiment is conducted using a public implementation of Faster RCNN. The mean Average Precision (mAP) is 82.8% when Intersection over Union (IoU) threshold equals to 0.5. Imbalanced data (i.e., imbalanced samples in each class) led to a decrease in the Average Precision in the minority class. Also, the symbol library, the small dataset, and the complex backbone network limit the generality of the model. Future work will focus on the collection of larger set of drawings and the improvement of the network’s geometric invariance.
EFFECTS OF THE LOCAL MICROMECHANICS AND ELECTROCHEMISTRY ON THE GALVANIC CORROSION OF AA7050-7451
Creators: name: Nicolas, Andrea
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace structures

description: The service life of aircraft structure, primarily composed of aluminum alloys, is markedly lower when galvanic corrosion is present due to early crack initiation at localized pitting, with the likelihood of cracking being higher at pits spanning several microns. To understand the joint effect that the mechanical and chemical behavior of AA7050-T7451 have on the evolution of corrosion prior and until its transition to cracking, the microstructure, constituent particles, mechanical strains, and the corrosion morphology were experimentally characterized using high-resolution methods and the mechanical stresses are computationally modeled at the micrometer level using a FFT-based crystal plasticity framework.
The material was corroded under both mechanically loaded and unloaded conditions under different corrosion intervals to properly capture the evolution of corrosion before, during, and after particle fallout. For the events prior to cracking, statistical cross-correlations between the mechanical state of the material and the corrosion morphology were performed to understand the mechanisms driving corrosion at its various stages. For the cracking event and its subsequent growth, the joint analysis of strains and stresses obtained from 3D crystal plasticity models were used to calculate Fatigue Indicator Parameters (FIPs) that can quantitatively give an insight of the major mechanisms driving crack initiation and growth in pre-corroded materials. The development of micromechanical models that account for both the environmental degradation and the microstructure in the material allowed to accurately predict the location of crack initiation arising from pits, which has been a longstanding problem in the field of corrosion. It is concluded that both corrosion growth and its transition to cracking are multivariable events, where corrosion growth is jointly driven by the local chemistry and the micromechanics, and crack initiation is driven by the coupled interaction between the corrosion geometry and the micromechanics.
sj-docx-5-cnr-10.1177_10547738211030602 – Supplemental material for Acupuncture for Sleep Disturbances in Post-Deployment Military Service Members: A Randomized Controlled Trial
Creators: name: Abanes, Jane J.
name: Ridner, Sheila H.
name: Dietrich, Mary S.
name: Hiers, Cynthia
name: Rhoten, Bethany
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-docx-5-cnr-10.1177_10547738211030602 for Acupuncture for Sleep Disturbances in Post-Deployment Military Service Members: A Randomized Controlled Trial by Jane J. Abanes, Sheila H. Ridner, Mary S. Dietrich, Cynthia Hiers and Bethany Rhoten in Clinical Nursing Research
The Flagellar Regulon of Legionella—A Review
Creators: name: Appelt, Sandra
name: Heuner, Klaus
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: 610 Medizin

description: The Legionella genus comprises more than 60 species. In particular, Legionella pneumophila is known to cause severe illnesses in humans. Legionellaceae are ubiquitous inhabitants of aquatic environments. Some Legionellaceae are motile and their motility is important to move around in habitats. Motility can be considered as a potential virulence factor as already shown for various human pathogens. The genes of the flagellar system, regulator and structural genes, are structured in hierarchical levels described as the flagellar regulon. Their expression is modulated by various environmental factors. For L. pneumophila it was shown that the expression of genes of the flagellar regulon is modulated by the actual growth phase and temperature. Especially, flagellated Legionella are known to express genes during the transmissive phase of growth that are involved in the expression of virulence traits. It has been demonstrated that the alternative sigma-28 factor is part of the link between virulence expression and motility. In the following review, the structure of the flagellar regulon of L. pneumophila is discussed and compared to other flagellar systems of different Legionella species. Recently, it has been described that Legionella micdadei and Legionella fallonii contain a second putative partial flagellar system. Hence, the report will focus on flagellated and non-flagellated Legionella strains, phylogenetic relationships, the role and function of the alternative sigma factor (FliA) and its anti-sigma-28 factor (FlgM).
Combined Proteomics/Genomics Approach Reveals Proteomic Changes of Mature Virions as a Novel Poxvirus Adaptation Mechanism
Creators: name: Grossegesse, Marica
name: Döllinger, Jörg
name: Tyshaieva, Alona
name: Schaade, Lars
name: Nitsche, Andreas
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: cowpox virus
subject: poxvirus
subject: adaptation
subject: proteomics
subject: genomics
subject: cell culture
subject: passaging
subject: 610 Medizin

description: DNA viruses, like poxviruses, possess a highly stable genome, suggesting that adaptation of virus particles to specific cell types is not restricted to genomic changes. Cowpox viruses are zoonotic poxviruses with an extraordinarily broad host range, demonstrating their adaptive potential in vivo. To elucidate adaptation mechanisms of poxviruses, we isolated cowpox virus particles from a rat and passaged them five times in a human and a rat cell line. Subsequently, we analyzed the proteome and genome of the non-passaged virions and each passage. While the overall viral genome sequence was stable during passaging, proteomics revealed multiple changes in the virion composition. Interestingly, an increased viral fitness in human cells was observed in the presence of increased immunomodulatory protein amounts. As the only minor variant with increasing frequency during passaging was located in a viral RNA polymerase subunit and, moreover, most minor variants were found in transcription-associated genes, protein amounts were presumably regulated at transcription level. This study is the first comparative proteome analysis of virus particles before and after cell culture propagation, revealing proteomic changes as a novel poxvirus adaptation mechanism.
Soziale Unterstützung als Ressource für Gesundheit in Deutschland
Creators: name: Borgmann, Lea-Sophie
name: Rattay, Petra
name: Lampert, Thomas
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: DEUTSCHLAND
subject: GESUNDHEITSMONITORING
subject: SOZIALE UNTERSTÜTZUNG
subject: RESSOURCEN
subject: SOZIALE LAGE
subject: 610 Medizin

description: Soziale Unterstützung resultiert aus sozialen Bindungen und Netzwerken. Als psychosoziale Ressource hat soziale Unterstützung einen wesentlichen Einfluss auf die Gesundheit. Sie kann u. a. das psychische Wohlbefinden verbessern, Stress reduzieren und die Auswirkung ungünstiger Lebensbedingungen verringern. Auf Basis der Erhebung GEDA 2014/2015-EHIS des Robert Koch-Instituts (RKI) wird das Ausmaß und die Verteilung wahrgenommener sozialer Unterstützung in der erwachsenen Bevölkerung Deutschlands untersucht (n = 23.617). Die Ergebnisse zeigen, dass sich Frauen und Männer zu einem großen Teil durch nahestehende Personen oder Nachbarn unterstützt fühlen. Soziale Unterstützung ist jedoch nicht in allen Bevölkerungsgruppen gleich verteilt: Ältere Personen, gering gebildete sowie nicht erwerbstätige Frauen und Männer berichten vergleichsweise häufig von geringer sozialer Unterstützung. Damit können insbesondere diejenigen Bevölkerungsgruppen, die häufiger von gesundheitlichen Problemen betroffen sind, seltener auf diese Ressource zurückgreifen.
Factors influencing vaccine hesitancy among United Kingdom adolescents in a senior high school environment and actions to address it
Creators: name: Drobniewski, Francis
name: Ashmi, Marcia
name: Ahmad, Raheelah
name: He, Changchunzi
name: Bogdanova, Marianna
name: Garbacz, Alan
name: Moustafa, Ahmed
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12–13 adolescents in London, UK. As the response rate was low (Cohort 1; n = 112/486, 23.0%), we repeated the survey with incoming students (cohort 2, n = 256/275; 93%). A focus group (n = 31) evaluated international HPV campaign posters. Cohort 1 participants were 82.1% female, 13.4% male, and ethnically diverse (32.1% Asian/Asian British, 29.5% Black/Black British, 25.9% White, 7.1% Mixed); Cohort 2 were 80% female, 18% male, with participants identifying as 38% Black/Black British, 34% Asian/Asian British, 15% White, 12% Mixed/Others. Across both cohorts, participants believed childhood vaccinations were safe (Cohort 1 = 95.8%, Cohort 2 = 91%). COVID-19 vaccination uptake was higher in Cohort 1 than 2 (76.8% vs 67%), with fewer participants believing it was adequately tested (56.3% vs 47%). Support for mandatory COVID-19 vaccination for healthcare workers (HCW) was high (Cohort 1:77.8–79% “all” vs “patient-facing HCWs;” Cohort 2 = 62–64%). Similar patterns were observed for mandatory influenza vaccination (Cohort 1: 62.5–66.7%; Cohort 2: 62–63%). Vaccination decisions in Cohort 2 were primarily influenced by parents (96%), healthcare providers (48%), and school friends (36%) (Cohort 1 = 30.2%, 19.6%, and 12%, respectively). Recommendations by doctors, experts and parents (but not politicians) and school-based vaccine availability boosted vaccine confidence. Social media had minimal impact. Most participants received HPV vaccine (Cohort 1 = 83.1%, Cohort 2 = 77.2%). International HPV posters received strong but mixed support; direct design input from the target group is needed to ensure the success of visual vaccine promotions.
Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance, but high azithromycin resistance
Creators: name: Buder, Susanne
name: Dudareva-Vizule, Sandra
name: Jansen, Klaus
name: Loenenbach, Anna
name: Nikisins, Sergejs
name: Sailer, Andrea
name: Guhl, Eva
name: Kohl, Peter K.
name: Bremer, Viviane
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2018
Subjects: subject: Antimicrobial resistance
subject: Neisseria gonorrhoeae
subject: Gonorrhoea
subject: Resistance surveillance
subject: 610 Medizin

description: Background: The widespread antimicrobial resistance of Neisseria gonorrhoeae is a serious problem for the treatment and control of gonorrhoea. Many of the previously effective therapeutic agents are no longer viable. Because N. gonorrhoeae infections are not reportable in Germany, only limited data on disease epidemiology and antimicrobial susceptibility patterns are available. The Gonococcal Resistance Network (GORENET) is a surveillance project to monitor trends in the antimicrobial susceptibility of N. gonorrhoeae in Germany in order to guide treatment algorithms and target future prevention strategies. Methods: Between April 2014 and December 2015, data on patient-related information were collected from laboratories nationwide, and susceptibility testing was performed on 537 N. gonorrhoeae isolates forwarded from the network laboratories to the Conciliar Laboratory for gonococci. Susceptibility results for cefixime, ceftriaxone, azithromycin, ciprofloxacin and penicillin were defined according to EUCAST 4.0 standards. Percentages, medians and interquartile ranges (IQR) were calculated. Results: Altogether, 90% of isolates were from men. The median age was 32 (IQR 25–44) years for men and 25 (IQR 22–40) years for women (p-value
Additional file 5 of Integrated transcriptomic and metabolomic analyses reveals anthocyanin biosynthesis in leaf coloration of quinoa (Chenopodium quinoa Willd.)
Creators: name: Zhang, Min
name: Li, Yueyou
name: Wang, Junling
name: Shang, Shaopu
name: Wang, Hongxia
name: Yang, Xinlei
name: Lu, Chuan
name: Wang, Mei
name: Sun, Xinbo
name: Liu, Xiaoqing
name: Wang, Xiaoxia
name: Wei, Boxiang
name: Lv, Wei
name: Mu, Guojun
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 5