cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules
Creators: name: Willett, Julian D.
name: Lawrence, Marlon G.
name: Altenburg, Michael K.
name: Bleasdale, Benjamin
name: Li, Feng
name: Ballou, Byron
name: Smithies, Oliver
name: Sanford, Ryan
name: Berg, Ulla B.
name: Wilder, Jennifer
name: Miner, Jeffrey H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Human kidneys contain ∼2 x 106 glomeruli that produce ∼180 L per day of primary filtrate. Downstream tubules reabsorb most of the water, salt, and desirable low-molecular weight substances, leaving 1 to 2 L per day of urine containing undesirable waste products. Currently, most investigators think that the primary filtrate is low in protein because fluid exiting the glomerulus passes through slits spanned by a diaphragm that acts as a low-porosity molecular sieve. Our experiments challenge this view; they show that size-dependent permeation into the glomerular basement membrane and into a gel-like coat that covers the slits, together with saturable tubular reabsorption, determines which macromolecules reach the urine. The slit diaphragm is essential for capillary structure but may not directly determine glomerular size selectivity.
Sustainability and food and nutrition security: An indicator-based vulnerability and resilience approach for the Mediterranean Region
Creators: name: Prosperi, Paolo
Publisher: name: Italian Review of Agricultural Economics
Year: 2016

description: Recurrent food crises and global change are critical issues that pushed food security and environmental sustainability to the top of the political agenda. Using the lens of a broad sustainability approach and recognizing the systemic dimension of sustainability, the thesis developed a multidimensional framework to identify metrics for assessing the sustainability of food systems and diets. Building on the theories of vulnerability and resilience, the Mediterranean Region presents a set of socioeconomic and biophysical drivers of change affecting the sustainability of the food system in its main functions providing food and nutrition security. Formalizing the food system as a dynamic complex system, several causal models of vulnerability were identified, describing the interactions where drivers of change directly affect food and nutrition security outcomes, disentangling exposure, sensitivity, and resilience. This theoretical approach was operationalized through the identification of a first suite of indicators. A reduced pool of metrics was then obtained through an expert-based Delphi survey, moving beyond subjective evaluation and reaching consensus.
description: Italian Review of Agricultural Economics, Vol 71 No 1 (2016): Vol 71, No 1 (Suppl.) (2016)
title: InfAct – Information for Action: Der Weg zu einem europäischen Gesundheitsinformationssystem
Creators: name: Fehr, Angela
name: Ziese, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Gesundheitssysteme in Europa stehen vor ähnlichen Herausforderungen. Zu diesen zählen der demografische Wandel, eine zunehmende Krankheitslast bei chronischen nichtübertragbaren Erkrankungen sowie gesundheitliche und Versorgungsungleichheiten. Vergleichbare[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Finite element numerical integration for first order approximations on multi-core architectures
Creators: name: Banaś, Krzysztof
name: Krużel, Filip
name: Bielański, Jan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Software (cs.MS)
subject: FOS: Computer and information sciences

description: The paper presents investigations on the implementation and performance of the finite element numerical integration algorithm for first order approximations and three processor architectures, popular in scientific computing, classical CPU, Intel Xeon Phi and NVIDIA Kepler GPU. A unifying programming model and portable OpenCL implementation is considered for all architectures. Variations of the algorithm due to different problems solved and different element types are investigated and several optimizations aimed at proper optimization and mapping of the algorithm to computer architectures are demonstrated. Performance models of execution are developed for different processors and tested in practical experiments. The results show the varying levels of performance for different architectures, but indicate that the algorithm can be effectively ported to all of them. The general conclusion is that the finite element numerical integration can achieve sufficient performance on different multi- and many-core architectures and should not become a performance bottleneck for finite element simulation codes. Specific observations lead to practical advises on how to optimize the kernels and what performance can be expected for the tested architectures.
Physical activity, low-grade inflammation, and psychological responses to the COVID-19 pandemic among older adults in England
Creators: name: Nejedly, Martin
name: Iob, Eleonora
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences

description: This study uses data from the English Longitudinal Study of Ageing (ELSA) to examine if older adults with low-grade inflammation and low physical activity engagement pre-pandemic were more susceptible to depression and anxiety during the pandemic. We will also test if changes in physical activity from before to during the pandemic were associated with mental health responses to the pandemic. Lastly, we will test if physical activity and its changes moderated the association between low-grade inflammation pre-pandemic and depression and anxiety during the pandemic.
Şirket birleşme ve devralmalarının getiri üzerinde etkisi ve İMKB'da bir uygulama / The stock return effects of mergers and acquisitions : Evidence from İstanbul Stock Exchange
Creators: name: Yilmaz, Metin
Publisher: name: Zenodo
Year: 2010
Subjects: Finansal varlık değerleme modeli
Getiri
Hisse senedi getirileri
İMKB
İşyeri devri
Şirket birleşmeleri
Financial asset evaluation model
Return
Stock returns
İstanbul Stock Exchange
Workplace transferring
Mergers

description: 2002-2008 döneminde Türkiye'de gerçekleşen şirket birleşme ve devralmalarının hisse senetleri İMKB'da işlem gören hisse senedi getirileri üzerine etkileri işlemin açıklanmasına dayalı olay penceresinde incelenmiştir. 51 adet örnek olayda açıklamaya dayalı olarak olay penceresinde gerçekleşen getiriler, söz konusu hisselerin Finansal Varlık Fiyatlama Modeline göre aynı dönemde beklenen getirisi ve İMKB-100 endeks getirisi ile karşılaştırılmıştır. = The study aims to analyze announcement effects of mergers and acquisitions in Turkey during the period from 2002 to 2008. The sample is comprised of 51 cases selected from E&Y database. The cumulative abnormal returns are calculated by comparing actual returns with the expected returns for the event window in each case. Target company shares usually provide positive abnormal returns especially prior to the announcement.
title: Verfügbarkeit von qualitativ hochwertigen Gesundheitsinformationen für Kinder und Jugendliche – Recherche im Rahmen des Projektes HeLi-D zur Förderung der Gesundheitskompetenz von Kindern mit hoher Diversität
Creators: name: Rauer, Eva Susanne
name: Semlitsch, Thomas
name: Gasteiger-Klicpera, Barbara
name: Maitz, Katharina
name: Burgmann, Sarah
name: Siebenhofer, Andrea
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Die Ergebnisse der „Österreichischen Gesundheitskompetenz Jugendstudie“, die vom Ludwig Boltzmann Institut durchgeführt wurde und an den „European Health Literacy Survey (HLS-EU) anschließt, zeigen eine Notwendigkeit der Verbesserung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Physicochemical code for quinary protein interactions in Escherichia coli
Creators: name: Lang, Lisa
name: Mowray, David
name: Mu, Xin
name: Choi, Seongil
name: Danielsson, Jens
name: Dokholyan, Nikolay V.
name: Oliveberg, Mikael
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: This study shows that the diffusive motions of proteins in live cells are by no means without control but follow simplistic physical−chemical rules that can be quantified and optimized through surface composition. Most strikingly, human proteins are observed to stick to the “foreign” environment of bacterial cells, whereas the bacterial analogue moves around freely. Even so, the human proteins can predictably be transformed to bacterial behavior with a few structurally benign surface mutations, and, conversely, the bacterial protein can be made to stick. The findings have not only fundamental implications for how protein function is controlled at the physical−chemical level but can also be used to adjust protein motion in Escherichia coli at will.
Rodenticides and Alternatives Focus Group
Creators: name: McAuliffe, William
name: Elmore, Holly
name: Green, Che
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: animal welfare
subject: focus group
subject: rodenticides

description: Rodenticides are a commonly used method of controlling and eliminating rodent populations, but they are known to have negative impacts on rodents, non-target animals, pets, and children. Rethink Priorities is exploring different avenues for advocating against the use of rodenticides, but relatively little is known about how consumers respond to related messages and arguments. This qualitative study will establish a foundation of understanding about how people who have used rodenticides react to different arguments against the use of rodenticides.
The effect of oral refeeding compared with nasogastric refeeding on the quality of care for patients hospitalised with an eating disorder: A systematic review
Creators: name: Bendall, Cassandra
name: Taylor, Nicholas
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 3210
subject: Nutrition and dietetics
classificationCode: 4206
subject: Public health

description: Aim: The aim of this systematic review was to compare the benefits and harms of nasogastric and oral-based refeeding on the quality of care, including effectiveness, safety, and patient experience, for patients hospitalised with an eating disorder. Methods: A systematic search for studies measuring comparative data between nasogastric and oral refeeding methods was conducted in August 2021. Title and abstracts and remaining full texts were screened by both authors. Risk of bias was evaluated using the PEDro scale, and overall quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluation narrative synthesis. Results: Seven studies (one randomised controlled trial, five non-randomised studies of interventions, and one qualitative study) with 917 participants were included. There was low certainty evidence that nasogastric refeeding resulted in no difference or a small increase in weekly weight gain, and moderate certainty of greater total weight gain, and very low certainty of increased length of stay compared to oral refeeding. There was no difference or a small increase in discharge weight and body mass index with nasogastric refeeding compared to oral refeeding. No serious adverse events were reported. Conclusion: Patients selected for nasogastric refeeding have a longer duration of illness and lower admission weight, making it difficult to determine which refeeding approach is superior. However, the lack of clear difference in weekly weight gain and the lack of reported harms suggests that other factors such as the normalisation of eating behaviour may be taken into account when choosing the most appropriate refeeding method.
Additional file 1 of Exploring the molecular mechanism of ginseng against anthracycline-induced cardiotoxicity based on network pharmacology, molecular docking and molecular dynamics simulation
Creators: name: Xie, Lin
name: Liu, Hanze
name: Zhang, Ke
name: Pan, Yijun
name: Chen, Mengyao
name: Xue, Xiangyue
name: Wan, Guoxing
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Supplementary Material 1.
The arc space of the Grassmannian
Creators: name: Docampo, Roi
name: Nigro, Antonio
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14E18, 14M15 (Primary), 14B05 (Secondary)

description: We study the arc space of the Grassmannian from the point of view of the singularities of Schubert varieties. Our main tool is a decomposition of the arc space of the Grassmannian that resembles the Schubert cell decomposition of the Grassmannian itself. Just as the combinatorics of Schubert cells is controlled by partitions, the combinatorics in the arc space is controlled by plane partitions (sometimes also called 3d partitions). A combination of a geometric analysis of the pieces in the decomposition and a combinatorial analysis of plane partitions leads to invariants of the singularities. As an application we reduce the computation of log canonical thresholds of pairs involving Schubert varieties to an easy linear programming problem. We also study the Nash problem for Schubert varieties, showing that the Nash map is always bijective in this case.
description: Minor corrections. Final version, to appear in Advances in Mathematics
Parameterized post-Newtonian limit of Horndeski's gravity theory
Creators: name: Hohmann, Manuel
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the parameterized post-Newtonian (PPN) limit of Horndeski's theory of gravity, also known under the name generalized G-inflation or $\text{G}^2$-inflation, which is the most general scalar-tensor theory of gravity with at most second order field equations in four dimensions. We derive conditions on the action for the validity of the post-Newtonian limit. For the most general class of theories consistent with these conditions we calculate the PPN parameters $γ(r)$ and $β(r)$, which in general depend on the interaction distance $r$ between the gravitating mass and the test mass. For a more restricted class of theories, in which the scalar field is massless, we calculate the full set of PPN parameters. It turns out that in this restricted case all parameters are constants and that the only parameters potentially deviating from observations are $γ$ and $β$. We finally apply our results to a number of example theories, including galileons and different models of Higgs inflation.
description: 33 pages, no figures; journal version
Plasmon-enhanced light-driven water oxidation by a dye-sensitized photoanode
Creators: name: Eberhart, Michael S.
name: Farnum, Byron H.
name: Sherman, Benjamin D.
name: Wang, Degao
name: Sheridan, Matthew V.
name: Dares, Christopher J.
name: Marquard, Seth L.
name: Meyer, Thomas J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Dye-sensitized photoelectrosynthesis cells (DSPECs) provide a basis for artificial photosynthesis and solar fuels production. By combining molecular chromophores and catalysts with high surface area, transparent semiconductor electrodes, a DSPEC provides the basis for light-driven conversion of water to O2 and H2 or for reduction of CO2 to carbon-based fuels. The incorporation of plasmonic cubic silver nanoparticles, with a strongly localized surface plasmon absorbance near 450 nm, to a DSPEC photoanode induces a great increase in the efficiency of water oxidation to O2 at a DSPEC photoanode. The improvement in performance by the molecular components in the photoanode highlights a remarkable advantage for the plasmonic effect in driving the 4e-/4H+ oxidation of water to O2 in the photoanode.
Anonconotus alpinus Yersin 1858
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Anonconotus
Anonconotus alpinus

description: Anonconotus alpinus (Yersin, 1858) Alpenschrecke VU B2a,B2b(iii,iv) Grünlandart
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238
title: Das evidenzbasierte GAP-Portal zur hausärztlichen Konsultation bei Rückenschmerz – nutzerorientierte Entwicklung und Pilotierung
Creators: name: Maun, Andy
name: Wollmann, Katharina
name: Serong, Julia
name: Henke, Jakob
name: van der Keylen, Piet
name: Voigt-Radloff, Sebastian
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Obwohl gute Information für die Arzt-Patienten-Konsultation (GAP) essentiell ist, vermissen sowohl Patienten als auch Ärzte für ihre informierte Entscheidungsfindung im Internet niedrigschwellige und vertrauenswürdige Informationsquellen. Die zusammengefasste[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Kekule versus hidden superconducting order in graphene-like systems: Competition and coexistence
Creators: name: Kunst, Flore K.
name: Delerue, Christophe
name: Smith, Cristiane Morais
name: Juricic, Vladimir
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We theoretically study the competition between two possible exotic superconducting orders that may occur in graphene-like systems, assuming dominant nearest-neighbor attraction: the gapless hidden superconducting order, which renormalizes the Fermi velocity, and the Kekule order, which opens a superconducting gap. We perform an analysis within the mean-field theory for Dirac electrons, at finite-temperature and finite chemical potential, as well as at half filling and zero-temperature, first excluding the possibility of the coexistence of the two orders. In that case, we find the dependence of the critical (more precisely, crossover) temperature and the critical interaction on the chemical potential. As a result of this analysis, we find that the Kekule order is preferred over the hidden order at both finite temperature and finite chemical potential. However, when the coexistence of the two superconducting orders is allowed, using the coupled mean-field gap equations, we find that above a critical value of the attractive interaction a mixed phase sets in, in which these orders coexist. We show that the critical value of the interaction for this transition is greater than the critical coupling for the hidden superconducting state in the absence of the Kekule order, implying that there is a region in the phase diagram where the Kekule order is favored as a result of the competition with the hidden superconducting order. The latter, however, eventually sets in and coexists with the Kekule state. According to our mean-field calculations, the transition from the Kekule to the mixed phase is of the second order, but it may become first order when fluctuations are considered. Finally, we investigate whether these phases could be possible in honeycomb superlattices of self-assembled semiconducting nanocrystals, which have been recently experimentally realized with CdSe and PbSe.
description: 15 pages, 9 figures, published version. Minor changes, new references added
Protein composition of the hepatitis A virus quasi-envelope
Creators: name: Lemon, Stanley M.
name: McKnight, Kevin L.
name: Rivera-Serrano, Efraín E.
name: González-López, Olga
name: Xie, Ling
name: Chen, Xian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The nonlytic cellular egress of picornaviruses in extracellular vesicles is likely to be important in disease pathogenesis, but the mechanism(s) underlying this process and the origins of the membranes surrounding virions exiting the cell are poorly understood. We describe a quantitative proteomics analysis of quasi-enveloped hepatitis A virus (eHAV) virions that shows capsids are selected as cargo for vesicular export via a highly specific process, and that infectious eHAV virions possess a host protein complement similar to that of exosomes with CD9 and DPP4 displayed on their surface. eHAV-associated proteins are highly enriched for endolysosomal components and lack markers of autophagy, suggesting an exosome-like mechanism of endosomal sorting complex required for transport-mediated eHAV biogenesis involving endosomal budding that is distinct from the autophagosome-mediated release proposed previously for enteroviruses.
title: Spelt can also trigger allergies - low level of public knowledge about spelt being a type of wheat: BfR Opinion No 001/2023 issued 13 January 2023 (assessment as of 30 November 2020)
Creators: name: Bundesinstitut Für Risikobewertung
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2023
Subjects: subject: 000

description: BfR-Stellungnahmen, vol. 2023, no. 001
Nobody Lives Here: Willful Ignorance and Property Rights in Dictator Games
Creators: name: Gately, J.
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Behavioral Economics
subject: Social and Behavioral Sciences
subject: Economics
subject: dictator games
subject: motivated reasoning
subject: property rights
subject: social preferences
subject: willful ignorance

description: I investigate whether willful ignorance and property rights have interactive effects on other-regarding behavior in dictator games.
Antaxius difformis Brunner von Wattenwyl 1861
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Antaxius
Antaxius difformis

description: Antaxius difformis (Brunner von Wattenwyl, 1861) Alpine Bergschrecke NT
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238
Non-Hermitian Heisenberg representation
Creators: name: Znojil, Miloslav
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In a way paralleling the recently accepted non-Hermitian version of quantum mechanics in its Schrödinger representation (working often with the innovative and heuristically productive concept of ${\cal PT}-$symmetry), it is demonstrated that it is also possible to construct an analogous non-Hermitian version of quantum mechanics in its Heisenberg representation.
description: 10 pp., prepared for the PHHQP XV conference in Palermo: http://www.math.unipa.it/~phhqp15/
Role for dithiolopyrrolones in disrupting bacterial metal homeostasis
Creators: name: Chan, Andrew N.
name: Razvi, Sayyeda Zeenat A.
name: Li, Bo
name: Traxler, Matthew F.
name: Wever, Walter J.
name: Shiver, Anthony L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Antibiotic resistance is a rising health threat worldwide, against which novel strategies are urgently needed. We have taken a systems approach to examine a potent and underexplored class of broad-spectrum antibiotics, the dithiolopyrrolones (DTPs). Our results indicate that DTPs disrupt cellular processes by high-affinity chelation of essential metal ions and inhibition of a subset of metalloenzymes. This mode of action is unique amongst antibiotics and may be further explored for treatment of multidrug-resistant infections. Our study also highlights chemical genomics as a powerful approach for the identification of antimicrobial mechanisms of action.
Signaling from the plasma-membrane localized plant immune receptor RPM1 requires self-association of the full-length protein
Creators: name: Wan, Li
name: El Kasmi, Farid
name: Dangl, Jeffery L.
name: Chung, Eui-Hwan
name: Eitas, Timothy K.
name: Anderson, Ryan G.
name: Gao, Zhiyong
name: Li, Jinyue
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Pathogen recognition first occurs at the plasma membrane, where receptor-like kinases perceive pathogen-derived molecules and initiate immune responses. To abrogate this immune response, pathogens evolved effector proteins that act as virulence factors, often following delivery to the host cell. Plants evolved intracellular receptors, known as NOD-like receptors (NLRs), to detect effectors, thereby ensuring activation of effector-triggered immunity. However, despite their importance in immunity, the molecular mechanisms underlying effector recognition and subsequent immune activation by membrane-localized NLRs remain to be fully elucidated. Our analyses reveal the importance of and need for self-association and the coordinated interplay of specific domains and conserved residues for NLR activity. This could provide strategies for crop improvement, contributing to effective, environmentally friendly, and sustainable solutions for future agriculture.
Antaxius pedestris Fabricius 1787
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Antaxius
Antaxius pedestris

description: Antaxius pedestris (Fabricius, 1787) Atlantische Bergschrecke NT
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238
Not motivated or too scared? The dissociable roles of trait anxiety and depression in social risk taking
Creators: name: Pei, Rui
name: zaki, jamil
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Developmental Psychology
subject: Sociology
subject: FOS: Sociology
subject: Psychology
subject: FOS: Psychology
subject: Social and Behavioral Sciences
subject: anxiety
subject: depression
subject: reward expectation
subject: risk perception
subject: risk taking
subject: social risk taking
subject: well-being

description: Please see the attached PDF (behavioral_social_risk_registration.pdf) for the preregistration.
Soft Proton Scattering Efficiency Measurements on X-Ray Mirror Shells
Creators: name: Diebold, S.
name: Tenzer, C.
name: Perinati, E.
name: Santangelo, A.
name: Freyberg, M.
name: Friedrich, P.
name: Jochum, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: In-orbit experience has shown that soft protons are funneled more efficiently through focusing Wolter-type optics of X-ray observatories than simulations predicted. These protons can degrade the performance of solid-state X-ray detectors and contribute to the instrumental background. Since laboratory measurements of the scattering process are rare, an experiment for grazing angles has been set up at the accelerator facility of the University of Tübingen. Systematic measurements at incidence angles ranging from 0.3° to 1.2° with proton energies around 250 keV, 500 keV, and 1 MeV have been carried out. Parts of spare mirror shells of the eROSITA (extended ROentgen Survey with an Imaging Telescope Array) instrument have been used as scattering targets. This publication comprises a detailed description of the setup, the calibration and normalization methods, and the scattering efficiency and energy loss results. A comparison of the results with a theoretical scattering description and with simulations is included as well.
description: 23 pages, 19 figures; accepted for publication in Experimental Astronomy
Single-stranded nucleic acid elasticity arises from internal electrostatic tension
Creators: name: McIntosh, Dustin B.
name: Saleh, Omar A.
name: Jacobson, David R.
name: Rubinstein, Michael
name: Stevens, Mark J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Charged, flexible polymers, such as single-stranded nucleic acids (ssNAs), are ubiquitous in biology and technology. Quantitative description of their solution conformation has remained elusive due to the competing effects of polymer configurational freedom and salt-screened electrostatic repulsion between monomers. We investigate this by measuring the elastic response of single ssNA molecules over a range of salt concentrations. The data are well described by a model, inspired by a mean-field approach, in which intrapolymer electrostatic repulsion creates a salt-dependent internal tension whose interplay with the external force determines the elasticity. The internal tension can be related to the polymer’s charge spacing; thus, our results show how mesoscopic polymer conformation emerges from microscopic structure.
Barbitistes obtusus Targioni-Tozzetti 1881
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Phaneropteridae
Barbitistes
Barbitistes obtusus

description: Barbitistes obtusus Targioni-Tozzetti, 1881 Südalpen-Säbelschrecke LC
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238
Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-β signaling
Creators: name: Feng, Xin-Hua
name: Lin, Xia
name: Gu, Shuchen
name: Chen, Fenfang
name: Li, Yi
name: Ding, Chen
name: Xu, Pinglong
name: Wang, Lei
name: Chen, Ye-Guang
name: Li, Wenjian
name: Xia, Zongping
name: Ye, Sheng
name: Xiao, Mu
name: Qin, Jun
name: Xu, Dewei
name: Zhao, Bin
name: Yu, Yi
name: Li, Ye
name: Sun, Chuang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: TGF-β and related growth factors critically regulate cell potency and functions. Smad7 is induced by TGF-βs and inhibits the physiological functions of TGF-β signaling. This study describes an unexpected finding that Smad7 promotes self-renewal of embryonic stem cells (ESCs) in a manner independent of its inhibition on TGF-β signaling. Instead, Smad7 acts to induce activation of transcription factor signal transducers and activators of transcription 3 (STAT3) in ESCs. Smad7 activates STAT3 through its direct binding to the cytokine receptor upstream of STAT3 activation. In agreement with the role of STAT3 in maintaining ESC pluripotency, Smad7 promotes ESC self-renewal and induced pluripotent stem cell reprogramming. This finding illustrates a regulatory mechanism for Smad7 in maintaining pluripotency, and likely in cancer and inflammation.
Nonparametric modeling and forecasting electricity demand: an empirical study
Creators: name: Shang, Han Lin
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: This paper uses half-hourly electricity demand data in South Australia as an empirical study of nonparametric modeling and forecasting methods for prediction from half-hour ahead to one year ahead. A notable feature of the univariate time series of electricity demand is the presence of both intraweek and intraday seasonalities. An intraday seasonal cycle is apparent from the similarity of the demand from one day to the next, and an intraweek seasonal cycle is evident from comparing the demand on the corresponding day of adjacent weeks. There is a strong appeal in using forecasting methods that are able to capture both seasonalities. In this paper, the forecasting methods slice a seasonal univariate time series into a time series of curves. The forecasting methods reduce the dimensionality by applying functional principal component analysis to the observed data, and then utilize an univariate time series forecasting method and functional principal component regression techniques. When data points in the most recent curve are sequentially observed, updating methods can improve the point and interval forecast accuracy. We also revisit a nonparametric approach to construct prediction intervals of updated forecasts, and evaluate the interval forecast accuracy.
Barbitistes serricauda Fabricius 1794
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Phaneropteridae
Barbitistes
Barbitistes serricauda

description: Barbitistes serricauda (Fabricius, 1794) Laubholz-Säbelschrecke LC
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238
title: Sichtweisen von Allgemeinmedizinern zu technischen Assistenzsystemen in Sachsen-Anhalt
Creators: name: Buhtz, Christian
name: Paulicke, Denny
name: Schwarz, Karsten
name: Jahn, Patrick
name: Stoevesandt, Dietrich
name: Frese, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Der Mangel an Ärztinnen und Ärzten sowie Pflegepersonal in Verbindung mit dem zahlenmäßigen Anstieg älterer Menschen stellt eine zunehmende Herausforderung dar. Im Besonderen für das Land Sachsen-Anhalt ist diese aufgrund von ausbleibender[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
title: Evidenzbasiertes labordiagnostisches Vorgehen bei Diabetes Mellitus Typ 2 in der vertragsärztlichen Versorgung
Creators: name: Markwart, Robby
name: Holthenrich, Anke
name: Müller, Kristin
name: Quast, Annika
name: Schiffner, Roman
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Mit einer Prävalenz von 6,7 Mio. Patienten und ca. 167.000 krankheitsassoziierten Todesfällen spielt der Diabetes mellitus Typ 2 (DM2) eine große Rolle bei der medizinischen Versorgung der rund 70 Mio. gesetzlich versicherten Personen in Deutschland. Evidenzbasierte[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Forecasting Compositional Time Series with Exponential Smoothing Methods
Creators: name: Koehler, Anne B.
name: Snyder, Ralph D.
name: Ord, J. Keith
name: Beaumont, Adrian
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: Compositional time series are formed from measurements of proportions that sum to one in each period of time. We might be interested in forecasting the proportion of home loans that have adjustable rates, the proportion of nonagricultural jobs in manufacturing, the proportion of a rock's geochemical composition that is a specific oxide, or the proportion of an election betting market choosing a particular candidate. A problem may involve many related time series of proportions. There could be several categories of nonagricultural jobs or several oxides in the geochemical composition of a rock that are of interest. In this paper we provide a statistical framework for forecasting these special kinds of time series. We build on the innovations state space framework underpinning the widely used methods of exponential smoothing. We couple this with a generalized logistic transformation to convert the measurements from the unit interval to the entire real line. The approach is illustrated with two applications: the proportion of new home loans in the U.S. that have adjustable rates; and four probabilities for specified candidates winning the 2008 democratic presidential nomination.
Conocephalus dorsalis Latreille 1804
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dryophthoridae
Conocephalus
Conocephalus dorsalis

description: Conocephalus dorsalis (Latreille, 1804) Kurzflüglige Schwertschrecke EN B2a, B2b(iii,iv) Sumpfart
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238
Statistical physics of loopy interactions: Independent-loop approximation and beyond
Creators: name: Ramezanpour, A.
name: Moghimi-Araghi, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Discrete Mathematics (cs.DM)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We consider an interacting system of spin variables on a loopy interaction graph, identified by a tree graph and a set of loopy interactions. We start from a high-temperature expansion for loopy interactions represented by a sum of nonnegative contributions from all the possible frustration-free loop configurations. We then compute the loop corrections using different approximations for the nonlocal loop interactions induced by the spin correlations in the tree graph. For distant loopy interactions, we can exploit the exponential decay of correlations in the tree interaction graph to compute loop corrections within an independent-loop approximation. Higher orders of the approximation are obtained by considering the correlations between the nearby loopy interactions involving larger number of spin variables. In particular, the sum over the loop configurations can be computed "exactly" by the belief propagation algorithm in the low orders of the approximation as long as the loopy interactions have a tree structure. These results might be useful in developing more accurate and convergent message-passing algorithms exploiting the structure of loopy interactions.
description: 21 pages, 6 figures, 2 appendices, typos corrected
title: How many physicians are rated on Swiss physician rating websites?
Creators: name: McLennan, Stuart
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: Physician rating websites (PRWs) are another sign of the growing digitalisation of the patient-health professional relationship and raise a number of important ethical and communication issues. International research has indicated that a key shortcoming of PRWs is [for full text, please go to the a.m. URL]
description: EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Bayesian Adaptive Bandwidth Kernel Density Estimation of Irregular Multivariate Distributions
Creators: name: Hu, Shuowen
name: Poskitt, D.S.
name: Zhang, Xibin
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: Kernel density estimation is an important technique for understanding the distributional properties of data. Some investigations have found that the estimation of a global bandwidth can be heavily affected by observations in the tail. We propose to categorize data into low- and high-density regions, to which we assign two different bandwidths called the low-density adaptive bandwidths. We derive the posterior of the bandwidth parameters through the Kullback-Leibler information. A Bayesian sampling algorithm is presented to estimate the bandwidths. Monte Carlo simulations are conducted to examine the performance of the proposed Bayesian sampling algorithm in comparison with the performance of the normal reference rule and a Bayesian sampling algorithm for estimating a global bandwidth. According to Kullback-Leibler information, the kernel density estimator with low-density adaptive bandwidths estimated through the proposed Bayesian sampling algorithm outperforms the density estimators with bandwidth estimated through the two competitors. We apply the low-density adaptive kernel density estimator to the estimation of the bivariate density of daily stock-index returns observed from the U.S. and Australian stock markets. The derived conditional distribution of the Australian stock-index return for a given daily return in the U.S. market enables market analysts to understand how the former market is associated with the latter.
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody
Creators: name: Basu, Shibom
name: Roth, Bryan L.
name: Weierstall, Uwe
name: Patel, Nilkanth
name: Zhang, Ai
name: Kapoor, Mili
name: Wacker, Daniel
name: Messerschmidt, Marc
name: Liu, Wei
name: Ishchenko, Andrii
name: Stevens, Raymond C.
name: Katritch, Vsevolod
name: Cherezov, Vadim
name: Han, Gye Won
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Highly selective monoclonal antibodies recognizing the extracellular 3D epitope of G protein-coupled receptors represent valuable tools for elucidating receptor function and localization in the cell and show promise for a range of therapeutic applications. Here we present the structure of a complex between the human serotonin 2B receptor, captured in an active-like state, and an antibody Fab fragment, bound to the extracellular side of the receptor. The structure uncovers the mechanisms of receptor activation and of extracellular receptor recognition by antibodies.
Conocephalus fuscus Fabricius 1793
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dryophthoridae
Conocephalus
Conocephalus fuscus

description: Conocephalus fuscus (Fabricius, 1793) Langflüglige Schwertschrecke VU B 2b(iii,iv) Sumpfart
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238
Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion
Creators: name: Tse, Longping Victor
name: Agbandje-McKenna, Mavis
name: Madigan, Victoria J.
name: Rivera, Ruth M. Castellanos
name: Smith, J. Kennon
name: Havlik, L. Patrick
name: Wells, Lindsey F.
name: Asokan, Aravind
name: Klinc, Kelli A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Preexisting neutralizing antibodies (NAbs) against adeno-associated viruses (AAVs) pose a major, unresolved challenge that restricts patient enrollment in gene therapy clinical trials using recombinant AAV vectors. To tackle this problem, we developed a structure-guided approach to evolve AAV variants with altered antigenic footprints that cannot be recognized by preexisting antibodies. These proof-of-principle studies demonstrate that synthetic AAV variants can be evolved to evade neutralizing sera from different species—mice, nonhuman primates, and humans—without compromising yield and transduction efficiency or altering tropism. Our approach provides a roadmap for engineering any AAV strain to evade NAbs in prospective patients for human gene therapy.
title: Efficacy and safety of allogeneic mesenchymal stem cells: a systematic review
Creators: name: Wolf, Sarah
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background/research question: Crohn’s disease (CD) is a chronic inflammatory condition characterised by transmural inflammation and skip lesions that can lead to (perianal) fistulas. In contrast to existing refractory therapies, allogeneic mesenchymal stem cells (MSCs) are assumed to prevent[for full text, please go to the a.m. URL]
description: EbM und Digitale Transformation in der Medizin; 20. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin
Localized exciton-polariton modes in dye-doped nanospheres: a quantum approach
Creators: name: Gentile, Martin J.
name: Horsley, Simon A. R.
name: Barnes, William L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We model a dye-doped polymeric nanosphere as an ensemble of quantum emitters and use it to investigate the localized exciton-polaritons supported by such a nanosphere. By determining the time evolution of the density matrix of the collective system, we explore how an incident laser field may cause transient optical field enhancement close to the surface of such nanoparticles. Our results provide further evidence that excitonic materials can be used to good effect in nanophotonics.
description: 16 pages, 4 figures
Decticus verrucivorus Linnaeus 1758
Creators: name: Monnerat, C.
name: Thorens, P.
name: Walter, T.
name: Gonseth, Y.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Decticus
Decticus verrucivorus

description: Decticus verrucivorus (Linnaeus, 1758) Warzenbeisser NT
description: Published as part of Monnerat C., Thorens P., Walter T. & Gonseth Y., 2007, Rote Liste der Heuschrecken der Schweiz, pp. 1-62 in Umwelt-Vollzug 7 (19) on page 34, DOI: 10.5281/zenodo.270238