cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Topic oysters Concept 4 - Grow-out systems and processes
Creators: name: Sühnel, Simone
Publisher: name: Zenodo
Year: 2022
Subjects: mollusc, oyster, low-trophic species, aquaculture, sustainability

description: Module on molluscs within AquaVitae´s MOOC (Massive Open Online Course), one of the training activities of the H202project. Overall objective of AquaVitaeMOOC: Enhance digitalization in teaching and sustainability in food production by developing a massive open online course (MOOC) on low trophic aquaculture, and thereby also provide material for teachers to utilize flipped classrooms in master level courses. Background During the COVID-19 pandemic, online courses, digital learning and flipped classrooms have become more important as physical teaching is no longer possible on a usual scale. As the pandemic has resulted in an increased unemployment, there is a growing need for training options, and the Norwegian government has requested that the universities increase student capacity with a total of 4000 places [1]. Increased need for training in the general public and online training at universities calls for new course content and new digital tools for learning. Online courses open up to students to study at their own pace and provide an alternative to traditional schooling that might not suit everyone. Moreover, online courses offer students the possibility to study a subject/discipline that might not be available for them through traditional schooling due to geographical or financial restrictions . Online learning opens for the possibility of flipped classrooms, a teaching method where instructors make lessons available to students to be accessed whenever and wherever they want. Flipped learning has the potential to transform higher education classrooms into dynamic, interactive learning environments where the teacher guides students as they apply concepts and engage creatively in the subject at hand. This approach provides more opportunities for students to develop communication skills and tackle unfamiliar problems.
AUT768484_Supplementary_material – Supplemental material for The prevalence of autistic traits in a homeless population
Creators: name: Churchard, Alasdair
name: Ryder, Morag
name: Greenhill, Andrew
name: Mandy, William
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: Education
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, AUT768484_Supplementary_material for The prevalence of autistic traits in a homeless population by Alasdair Churchard, Morag Ryder, Andrew Greenhill and William Mandy in Autism
La Corte Costituzionale e la legge regionale lombarda: cronaca di una morte annunciata o di un'opportunità mancata?
Creators: name: Oliosi, Francesca
Publisher: name: Università degli Studi di Milano
Year: 2016
Subjects: Edifici ed edilizia di culto

description: Contributo sottoposto a valutazione.
SOMMARIO: 1. Ora come allora: “Le leggi son, ma chi pon mano ad esse?” - 2. L’oggetto del giudizio: la "legge antimoschea" - 3. Le doglianze del Governo e la difesa della Regione: l'eterno conflitto tra libertà e sicurezza - 3.1. “Confessione è chi la confessione fa”. I destinatari della norma, tra illegittima discriminazione e necessaria distinzione - 3.2. Esiste il principio di leale collaborazione tra gli enti (in Lombardia)? - 3.3. Contro la discrezionalità: del popolo (referendum), della norma (“il paesaggio lombardo”) e dei comuni (facoltà e non obbligo di prevedere attrezzature religiose) - 4. La parola alla Corte - 4.1 I prolegomena della sentenza: le premesse che, purtroppo, ancora occorrono - 4.2 Laratio oltre la littera: sull’incostituzionalità dei requisiti aggiuntivi per il “coacervo degli indistinti”, la richiesta di pareri “riguardanti la pubblica sicurezza” e l'impianto di videosorveglianza - 4.3 Convenzioni, referendum e congruità architettonica lombarda: quella pericolosa (ma costituzionale) attenzione per il particolare (rectius locale) sul generale - 5. Profili critici: tirannia del diritto di libertà religiosa o pericoloso bilanciamento? - 6. Errare è umano, perseverare è … politico.
description: Stato, Chiese e pluralismo confessionale, 2016: 24 ottobre
L’istruzione religiosa in Turchia: gli Aleviti e la Corte Europea dei Diritti Umani
Creators: name: Parrilli, Anna
Publisher: name: Università degli Studi di Milano
Year: 2016
Subjects: Corte europea dei Diritti dell'Uomo

description: Contributo sottoposto a valutazione.  SOMMARIO: 1. Breve premessa sull’insegnamento della religione in Europa - 2. La Corte Europea dei Diritti Umani e l’istruzione religiosa - 3. Scuola e religione in Turchia - 4. Alevismo e istruzione religiosa: il caso “Hasan e Eylem Zengin c. Turchia” - 5. La reazione alle sentenze in Turchia e in Europa - 6. Conclusione.ABSTRACT: Religious education has become a topic of great interest in the last two decades in Turkey as the result of the rulings of national and international courts and the pressure by non-Muslim communities for the recognition of their rights. The Alevi’s struggle for religious education to ensure respect for parental beliefs, in line with the European Convention on Human Rights, has attracted great attention through the applications of some Alevi citizens to the European Court of Human Rights (ECtHR), which contributed to the raising of public debate on the relationship between the State, the education system and religion. This work is aimed at understanding the position taken by the Strasbourg Court on religious education in Turkey in 2007 by analysing the pioneering case Hasan and Eylem Zengin v. Turkey, which set the case law, and reflecting on the impact that the judgment had both in Turkey and in Europe.
description: Stato, Chiese e pluralismo confessionale, 2016: 24 ottobre
Supplementary document for Double spiral resonant MEMS scanning for ultra-high-speed miniaturized optical microscopy - 6541508.pdf
Creators: name: Li, Linyang
name: Liang, Xiao
name: Qin, Wei
name: Guo, Heng
name: Qi, Weizhi
name: Jin, Tian
name: Tang, Jianbo
name: Xi, Lei
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Biomedical Engineering not elsewhere classified

description: Supplement 1
title: An Embarrassingly Simple Method to Mitigate Undesirable Properties of Pretrained Language Model Tokenizers
Creators: name: Muresan (Ed.), Smarandakov
name: Nakov (Ed.), Preslav
name: Villavicencio (Ed.), Aline
Publisher: name: Association for Computational Linguistics
Year: 2022

description: We introduce FLOTA (Few Longest Token Approximation), a simple yet effective method to improve the tokenization of pretrained language models (PLMs). FLOTA uses the vocabulary of a standard tokenizer but tries to preserve the morphological structure of words during tokenization. We evaluate FLOTA on morphological gold segmentations as well as a text classification task, using BERT, GPT-2, and XLNet as example PLMs. FLOTA leads to performance gains, makes inference more efficient, and enhances the robustness of PLMs with respect to whitespace noise.
Design of a potent, selective, and brain-penetrant inhibitor of Wnt-deactivating enzyme Notum by optimization of a crystallographic fragment hit.
Creators: name: Willis, Nicky J
name: Mahy, William
name: Sipthorp, James
name: Zhao, Yuguang
name: Woodward, Hannah L
name: Atkinson, Benjamin N
name: Bayle, Elliott D
name: Svensson, Fredrik
name: Frew, Sarah
name: Jeganathan, Fiona
name: Monaghan, Amy
name: Benvegnù, Stefano
name: Jolly, Sarah
name: Vecchia, Luca
name: Ruza, Reinis R
name: Kjær, Svend
name: Howell, Steven
name: Snijders, Ambrosius P
name: Bictash, Magda
name: Salinas, Patricia C
name: Vincent, Jean-Paul
name: Jones, E Yvonne
name: Whiting, Paul
name: Fish, Paul V
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Model organisms
subject: Biochemistry & Proteomics
subject: Synthetic Biology
subject: Imaging
subject: Signalling & Oncogenes
subject: Genetics & Genomics
subject: Developmental Biology
subject: Structural Biology & Biophysics
subject: Cell Biology
subject: Chemical Biology & High Throughput
subject: Computational & Systems Biology

description: Notum is a carboxylesterase that suppresses Wnt signaling through deacylation of an essential palmitoleate group on Wnt proteins. There is a growing understanding of the role Notum plays in human diseases such as colorectal cancer and Alzheimer's disease, supporting the need to discover improved inhibitors, especially for use in models of neurodegeneration. Here, we have described the discovery and profile of 8l (ARUK3001185) as a potent, selective, and brain-penetrant inhibitor of Notum activity suitable for oral dosing in rodent models of disease. Crystallographic fragment screening of the Diamond-SGC Poised Library for binding to Notum, supported by a biochemical enzyme assay to rank inhibition activity, identified 6a and 6b as a pair of outstanding hits. Fragment development of 6 delivered 8l that restored Wnt signaling in the presence of Notum in a cell-based reporter assay. Assessment in pharmacology screens showed 8l to be selective against serine hydrolases, kinases, and drug targets.
D2.4 - Policy White Paper: Advancing Next-Generation Sequencing and Public Health Genomics in European Healthcare Systems
Creators: name: Denis Horgan
name: Skarpa, Andela
name: De Las Heras Martin, Ane
name: Radovnikovic, Paola
Publisher: name: Zenodo
Year: 2025
Subjects: CAN.HEAL
public health
policy
healthcare policy
genomics
health equity
healthcare innovation
reimbursement
data governance
next-generation sequencing
precision medicine

description: This policy white paper, developed under the EU4Health-funded CAN.HEAL project (101080009), offers a strategic analysis of the integration of Next-Generation Sequencing (NGS) and Public Health Genomics (PHG) in European healthcare systems. Drawing from expert consensus and peer-reviewed research, the document identifies disparities in implementation across Europe, and outlines key policy, infrastructure, and data governance challenges. It provides actionable recommendations for EU and national policymakers, healthcare providers, researchers, and patient advocacy groups. The paper emphasizes the need for harmonized regulatory frameworks, workforce development, equitable access to genomic services, and cross-border data interoperability, positioning genomics as a cornerstone of future precision healthcare in Europe.
Updated_Methodology_Reporting_Kang_and_Lakshmanan – Supplemental material for Narcissism and Self- Versus Recipient-Oriented Imagery in Charitable Giving
Creators: name: Kang, Esther
name: Lakshmanan, Arun
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Updated_Methodology_Reporting_Kang_and_Lakshmanan for Narcissism and Self- Versus Recipient-Oriented Imagery in Charitable Giving by Esther Kang and Arun Lakshmanan in Personality and Social Psychology Bulletin
Table S1 from Vocal babbling in a wild parrot shows life history and endocrine affinities with human infants
Creators: name: Eggleston, Rory
name: Viloria, Nurialby
name: Delgado, Soraya
name: Mata, Astolfo
name: Guerrero, Hilda Y.
name: Kline, Richard J.
name: Beissinger, Steven R.
name: Berg, Karl S.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Developmental Biology
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Models predicting eight spectrographic measurements on vocal babbling. Akaike Information Criteria (AIC) scores are based on Generalized Linear Mixed Models. For each dependent variable there is an AIC analysis that included eight main factors, each in separate models; nest origin was included as a random factor in each. These eight main factors were combined in more complex models (Full Models) and AIC analysis repeated for each dependent variable. Hatch refers to the hatching sequence; Treatment refers to CORT, Oil and Control; Period refers to CORT-treatment period (20-26 days vs. 27-36 days post hatch); Brood refers to number of nestlings in each brood; Age refers to age of nestlings in days post hatch; Year refers to 2017 or 2018; Sex refers to Female or Male; Random refers to a intercept only model.
A possible approach to overcome the systemic toxicity of azathioprine (AZA) through nanoemulgel
Creators: name: Sah, Bikash Kumar
name: Ahmad, Faiz
name: Singh, Sachin Kumar
name: Kumar, Ankit
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2025
Subjects: azathioprine
nanoemulgel

description: EXCLI Journal; 24:Doc450; ISSN 1611-2156
Supplemental Appendix - Postthrombotic Syndrome in Patients Treated With Rivaroxaban or Warfarin for Venous Thromboembolism
Creators: name: Coleman, Craig I.
name: Beyer-Westendorf, Jan
name: Bunz, Thomas J.
name: Mahan, Charles E.
name: Spyropoulos, Alex C.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Cardiology
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental Appendix for Postthrombotic Syndrome in Patients Treated With Rivaroxaban or Warfarin for Venous Thromboembolism by Craig I. Coleman, Jan Beyer-Westendorf, Thomas J. Bunz, Charles E. Mahan, and Alex C. Spyropoulos in Clinical and Applied Thrombosis/Hemostasis
Women in Tech as Change Agents: Synthesizing Equity through Disruption
Creators: name: C. Chesher, William
name: D. Hernandez, Isabella
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 390306
subject: Secondary education
classificationCode: 390201
subject: Education policy
classificationCode: 390203
subject: Sociology of education
classificationCode: 460906
subject: Information systems education
classificationCode: 390407
subject: Inclusive education
classificationCode: 390406
subject: Gender, sexuality and education
classificationCode: 390405
subject: Educational technology and computing
classificationCode: 390403
subject: Educational administration, management and leadership
classificationCode: 390113
subject: Science, technology and engineering curriculum and pedagogy

description: Young women remain underrepresented in high school technology pathways. This study examined whether youth-led, equity-focused interventions could disrupt that pattern in a California career academy. Guided by research questions on participation (RQ1), identity development (RQ2), and sustainable change (RQ3), a diverse team of young women used empathy interviews, thematic analysis, and iterative Plan-Do-Study-Act (PDSA) cycles to investigate barriers and design solutions. As their work evolved, students shifted from isolated interventions to whole-system redesign through an approach we call Improvement Synthesis.Key interventions included a sensory-aware recruitment event, a student-led mentorship program, and the She‑Legacy framework for leadership succession. Female sophomore enrollment increased from 40% to 71%, mentorship became institutionalized through the WIT Ambassadors and Women’s Council, and equity-centered leadership structures were sustained beyond any single cohort. Participants reported increased confidence, agency, and belonging.Findings show that when young women are trusted to lead inquiry and implementation, they build systems that remove barriers faster than top-down efforts. Student-driven Improvement Synthesis offers a replicable model for achieving rapid, lasting gains in gender equity. Schools seeking systemic change in tech education should consider student co-leadership not as a supplement, but as a central strategy.
MAKTABGACHA TA'LIMDA ZAMONAVIY YONDASHUVLARNI AMALGA OSHIRISHNING SHART-SHAROITLARI
Creators: name: Djurayeva, Sharofatxon
Publisher: name: Zenodo
Year: 2025

description: oʻtgan davr mobaynida mamlakatimizda oʻsib borayotgan yosh avlodni sogʻlom va har tomonlama yetuk voyaga yetkazish, taʼlim-tarbiya jarayoniga samarali taʼlim va tarbiya shakllari hamda usullarini joriy etishga qaratilgan maktabgacha taʼlimning samarali tizimini tashkil etish boʻyicha keng koʻlamli ishlar amalga oshirilib kelmoqda. Ushbu maqolada, maktabgacha ta’limda zamonaviy yondashuvlarni amalga oshirishning ahamiyati va shart-sharoitlari xaqida ma’lumotlar beriladi.
Module Molluscs Topic oysters Concept 4 - Grow-out systems and processes
Creators: name: Strand, Åsa
Publisher: name: Zenodo
Year: 2022
Subjects: mollusc, oyster, low-trophic species, aquaculture, sustainability, MOOC

description: Module on molluscs within AquaVitae´s MOOC (Massive Open Online Course), one of the training activities of the H202project. Overall objective of AquaVitaeMOOC: Enhance digitalization in teaching and sustainability in food production by developing a massive open online course (MOOC) on low trophic aquaculture, and thereby also provide material for teachers to utilize flipped classrooms in master level courses. Background During the COVID-19 pandemic, online courses, digital learning and flipped classrooms have become more important as physical teaching is no longer possible on a usual scale. As the pandemic has resulted in an increased unemployment, there is a growing need for training options, and the Norwegian government has requested that the universities increase student capacity with a total of 4000 places [1]. Increased need for training in the general public and online training at universities calls for new course content and new digital tools for learning. Online courses open up to students to study at their own pace and provide an alternative to traditional schooling that might not suit everyone. Moreover, online courses offer students the possibility to study a subject/discipline that might not be available for them through traditional schooling due to geographical or financial restrictions . Online learning opens for the possibility of flipped classrooms, a teaching method where instructors make lessons available to students to be accessed whenever and wherever they want. Flipped learning has the potential to transform higher education classrooms into dynamic, interactive learning environments where the teacher guides students as they apply concepts and engage creatively in the subject at hand. This approach provides more opportunities for students to develop communication skills and tackle unfamiliar problems.
Supplementary document for Silver Nanoparticles-induced Enhancement of Light Extraction in Two-dimensional Light-emitting Diodes - 6541523.pdf
Creators: name: Liu, Tianqi
name: Fu, Qiang
name: Li, Yuanzhe
name: Han, Xu
name: Wang, Shixuan
name: Taniguchi, Takashi
name: Watanabe, Kenji
name: Wan, Dongyang
name: Zhang, Qi
name: Zhao, Yingbo
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: 9 additional figures and 2 tables
Additional file 1 of Effect evaluation of outpatient long-term video EEGs for people with seizure disorders – study protocol of the ALVEEG project: a randomized controlled trial in Germany
Creators: name: Münchenberg, Pauline Sarah
name: Schulz, Ricarda Sophia
name: Wainwright, Kerstin
name: Mayer, Imke
name: Holtkamp, Martin
name: Meisel, Christian
name: Kurth, Tobias
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1.
Additional file 1 of Purification and characterization of soluble recombinant Crimean-Congo hemorrhagic fever virus glycoprotein Gc expressed in mammalian 293F cells
Creators: name: Makoah, Nigel Aminake
name: Litabe, Matefo Millicent
name: Simo, Fredy Brice Nemg
name: Maboho, Katlego Keith
name: Burt, Felicity Jane
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 1
title: Animais, plantas e a crítica do antropocentrismo no Livro do desassossego, de Fernando Pessoa
Creators: name: Mendes, Victor K.
Publisher: name: IELT – Instituto de Estudos de Literatura e Tradição, Faculdade de Ciências Sociais e Humanas, Universidade NOVA de Lisboa
Year: 2015

description: Este artigo, influenciado inicialmente pela leitura de Carrie Rohman, Stalking the Subject: Modernism and the Animal (2009), mostra como a interpretação detalhada de alguns trechos do Livro do desassossego, escrito entre 1913 e 1934 por Fernando Pessoa, produz uma crítica do antropocentrismo ocidental e do humanismo em sentido lato, servida por uma precisa e recorrente redução ao absurdo (reductio ad absurdum é a expressão erudita que Pessoa usa) duma versão muito específica da humanidade ambiental pós-darwniana, identificada principalmente com animais e plantas.
description: Mendes, Victor K. (2015). Animais, plantas e a crítica do antropocentrismo no Livro do desassossego, de Fernando Pessoa. Revista Estranhar Pessoa, 2: 175–205. ISSN 2183-4075.
title: ÐÐ¾Ð²ÑÑÐµÐ½Ð¸Ðµ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¾Ñ ÑÐ°Ð½Ð¾Ð¹ ÑÑÑÐ´Ð° Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸ÐµÐ¼ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð´Ð»Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ ÑÑÑÐ´Ð° (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ ÐÑÐ»Ð¾Ð²ÑÐºÐ¾Ð¹ Ð¾Ð±Ð»Ð°ÑÑÐ¸)
title: ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÑ 2.10.3. ÐÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑ ÑÑÑÐ´Ð°
titleType: Subtitle
Creators: name: Ð¤ÑÐ¾Ð»Ð¾Ð², ÐÐ½ÑÐ¾Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: ÐÑ ÑÐ°Ð½Ð° ÑÑÑÐ´Ð°
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description: ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð¾ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð¾Ð»Ð¾Ð¶ÐµÐ½Ð¸Ð¹ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¾ÑÑÐ°Ð½Ð¾Ð¹ ÑÑÑÐ´Ð° Ð¸ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð´Ð»Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ ÑÑÑÐ´Ð°. Ð Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ°Ñ Ð¼Ð¾Ð´ÐµÐ»Ñ Ð½Ð°ÑÐ¾Ð¶Ð´ÐµÐ½Ð¸Ñ Ð¾Ð¿ÑÐ¸Ð¼Ð°Ð»ÑÐ½Ð¾Ð¹ Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÑÑÐ¾Ð²ÑÑ Ð²Ð¾Ð¿ÑÐ¾ÑÐ¾Ð² Ð² Ð·Ð°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¾Ñ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² ÑÐµÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ ÑÑÑÐ´Ð°, Ð²ÐºÐ»ÑÑÐ°ÑÑÐ°Ñ Ð² ÑÐµÐ±Ñ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¼Ð¾Ð´ÐµÐ»Ð¸ Ð»Ð¸Ð½ÐµÐ¹Ð½Ð¾Ð¹ ÑÐµÐ³ÑÐµÑÑÐ¸Ð¸ ÑÐ¾Ð²Ð¼ÐµÑÑÐ½Ð¾ Ñ Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼ Ð³ÑÐ°Ð´Ð¸ÐµÐ½ÑÐ½Ð¾Ð³Ð¾ ÑÐ¿ÑÑÐºÐ°, Ð¸ÑÐ¿Ð¾Ð»ÑÐ·ÑÐµÐ¼Ð°Ñ Ð² Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ Ð¾Ð±ÑÑÐ°ÑÑÐµÐ¹ ÑÐ¸ÑÑÐµÐ¼Ðµ Ð¡ÐÐ­ÐÐÐ¢. Ð Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð° Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ° Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¿ÑÐ»ÑÑÐ¾ÐºÑÐ¸Ð¼ÐµÑÑÐ°, Ð²ÐºÐ»ÑÑÐ°ÑÑÐ°Ñ Ð² ÑÐµÐ±Ñ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼ ÑÐµÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐºÐ¾ÑÐ¾ÑÑÐ¸ ÑÐµÐ°ÐºÑÐ¸Ð¸ Ð´Ð»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÐ¾Ð¼Ð»ÑÐµÐ¼Ð¾ÑÑÐ¸ Ð¾Ð±ÑÑÐ°ÑÑÐ¸ÑÑÑ Ð¸ Ð¸Ð½ÑÐµÐ³ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð°Ñ Ð² Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð¾Ð±ÑÑÐ°ÑÑÑÑ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¡ÐÐ­ÐÐÐ¢, Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑÐ°Ñ ÐºÐ¾ÑÑÐµÐºÑÐ¸ÑÐ¾Ð²Ð°ÑÑ Ð¿ÑÐ¾ÑÐµÑÑ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ ÑÑÑÐ´Ð° Ð´Ð»Ñ ÑÑÐ¿ÐµÑÐ½Ð¾Ð³Ð¾ ÐµÐ³Ð¾ Ð¿ÑÐ¾ÑÐ¾Ð¶Ð´ÐµÐ½Ð¸Ñ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ð´Ð°Ð½Ð½ÑÑ. Ð ÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ, Ð¿Ð¾Ð´ÑÐ²ÐµÑÐ¶Ð´ÐµÐ½Ð½ÑÐµ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½ÑÐ¼Ð¸ Ð´Ð°Ð½Ð½ÑÐ¼Ð¸, Ð¿Ð¾ÐºÐ°Ð·ÑÐ²Ð°ÑÑ, ÑÑÐ¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð´Ð»Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ ÑÑÑÐ´Ð° Ð¿Ð¾Ð²ÑÑÐ°ÐµÑ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¾ÑÑÐ°Ð½Ð¾Ð¹ ÑÑÑÐ´Ð° Ð¸ Ð¿ÑÐ¸Ð²Ð¾Ð´Ð¸Ñ Ðº ÑÐ½Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ°Ð²Ð¼Ð°ÑÐ¸Ð·Ð¼Ð°.
A single-molecule strategy to capture non-native intramolecular and intermolecular protein disulfide bridges.
Creators: name: Mora, Marc
name: Board, Stephanie
name: Languin-Cattoën, Olivier
name: Masino, Laura
name: Stirnemann, Guillaume
name: Garcia-Manyes, Sergi
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: Biochemistry & Proteomics
Imaging
Structural Biology & Biophysics
Cell Biology
Chemical Biology & High Throughput

description: Non-native disulfide bonds are dynamic covalent bridges that form post-translationally between two cysteines within the same protein (intramolecular) or with a neighboring protein (intermolecular), frequently due to changes in the cellular redox potential. The reversible formation of non-native disulfides is intimately linked to alterations in protein function; while they can provide a mechanism to protect against cysteine overoxidation, they are also involved in the early stages of protein multimerization, a hallmark of several protein aggregation diseases. Yet their identification using current protein chemistry technology remains challenging, mainly because of their fleeting reactivity. Here, we use single-molecule spectroscopy AFM and molecular dynamics simulations to capture both intra- and intermolecular disulfide bonds in γD-crystallin, a cysteine-rich, structural human lens protein involved in age-related eye cataracts. Our approach showcases the power of mechanical force as a conformational probe in dynamically evolving proteins and presents a platform to detect non-native disulfide bridges with single-molecule resolution.
Supplementary document for Deep sound-field denoiser: optically-measured sound-field denoising using deep neural network - 6541703.pdf
Creators: name: Ishikawa, Kenji
name: Takeuchi, Daiki
name: Harada, Noboru
name: Moriya, Takehiro
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Stick or twist? Cost-effectiveness of siponimod compared with continuing existing disease-modifying therapies in the treatment of active secondary progressive multiple sclerosis in the UK
Creators: name: Montgomery, S.
name: Woodhouse, F.
name: Vudumula, U.
name: Gudala, K.
name: Duddy, M.
name: Kroes, M.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Identification of the phenotypic transition from relapsing-remitting multiple sclerosis (RRMS) to secondary progressive multiple sclerosis (SPMS) is often delayed due to disease complexity and an unwillingness to withdraw RRMS disease-modifying therapies (DMTs), driven by limited SPMS treatment options. Despite the paucity of clinical evidence for efficacy in patients with SPMS, DMTs licensed for RRMS are frequently continued into the early stages of SPMS. The cost-effectiveness of oral siponimod, an active SPMS DMT, versus continued oral or infused RRMS DMTs for patients with active SPMS, was evaluated. A cohort Markov model based on disease progression through Expanded Disability Status Scale health states, with annual cycles and lifetime horizon, was employed to determine the cost-effectiveness of siponimod from a UK National Health Service (NHS) perspective for patients with active SPMS. Baseline characteristics, health state utility values, hazard ratios for time to 6-month confirmed disability progression, annualized relapse rate ratios and adverse events for siponimod were obtained from the phase 3 EXPAND clinical trial, supplemented by published literature. Published costs, resource use data and comparator efficacy data were obtained from the literature and, in the absence of data, reasonable assumptions were made. Quality-adjusted life years (QALYs) were greater for siponimod versus all comparators (3.45 versus 2.69–2.83). Incremental cost-effectiveness ratios (ICERs), calculated as cost per QALY, for siponimod versus natalizumab (dominant), ocrelizumab (£4,760), fingolimod (£10,033) and dimethyl fumarate (£15,837) indicated that siponimod was cost-effective at the commonly accepted willingness-to-pay threshold of £30,000/QALY. Recognition of active SPMS and treatment of this phenotype with siponimod offers a cost-effective and clinically beneficial treatment approach compared with the continuation of oral or infused RRMS DMTs.
Stick or twist? Cost-effectiveness of siponimod compared with continuing existing disease-modifying therapies in the treatment of active secondary progressive multiple sclerosis in the UK
Creators: name: Montgomery, S
name: Woodhouse, F
name: Vudumula, U
name: Gudala, K
name: Duddy, M
name: Kroes, M
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Identification of the phenotypic transition from relapsing-remitting multiple sclerosis (RRMS) to secondary progressive multiple sclerosis (SPMS) is often delayed due to disease complexity and an unwillingness to withdraw RRMS disease-modifying therapies (DMTs), driven by limited SPMS treatment options. Despite the paucity of clinical evidence for efficacy in patients with SPMS, DMTs licensed for RRMS are frequently continued into the early stages of SPMS. The cost-effectiveness of oral siponimod, an active SPMS DMT, versus continued oral or infused RRMS DMTs for patients with active SPMS, was evaluated. A cohort Markov model based on disease progression through Expanded Disability Status Scale health states, with annual cycles and lifetime horizon, was employed to determine the cost-effectiveness of siponimod from a UK National Health Service (NHS) perspective for patients with active SPMS. Baseline characteristics, health state utility values, hazard ratios for time to 6-month confirmed disability progression, annualized relapse rate ratios and adverse events for siponimod were obtained from the phase 3 EXPAND clinical trial, supplemented by published literature. Published costs, resource use data and comparator efficacy data were obtained from the literature and, in the absence of data, reasonable assumptions were made. Quality-adjusted life years (QALYs) were greater for siponimod versus all comparators (3.45 versus 2.69–2.83). Incremental cost-effectiveness ratios (ICERs), calculated as cost per QALY, for siponimod versus natalizumab (dominant), ocrelizumab (£4,760), fingolimod (£10,033) and dimethyl fumarate (£15,837) indicated that siponimod was cost-effective at the commonly accepted willingness-to-pay threshold of £30,000/QALY. Recognition of active SPMS, and treatment of this phenotype with siponimod offers a cost-effective and clinically beneficial treatment approach compared with continuation of oral or infused RRMS DMTs.
Evaluating parental perceptions of written handbooks provided during shared decision making with parents anticipating extremely preterm birth
Creators: name: Mardian, Emily
name: Bucking, Shannon
name: Dunn, Sandra
name: Lemyre, Brigitte
name: Daboval, Thierry
name: Moore, Gregory P.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Medicine
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Statistics
subject: FOS: Mathematics
subject: 111714 Mental Health
subject: FOS: Health sciences

description: To explore parental perceptions of written handbooks provided to them during antenatal counseling for anticipated extremely preterm birth. This study involved a prospective convenience sample of parents anticipating delivery between 22 weeks + 0 days and 25 weeks + 6 days gestation. The antenatal counseling involved a shared decision-making process. In-person interviews were conducted using a semi-structured interview guide to gather feedback about new parent handbooks developed to support decision making. The questions during the semi-structured interview targeted seven main themes: overall impression, timing, graphs/tables, formatting, imagery, ease of use and understanding, and content. The interviews followed an antenatal consultation and provision of the appropriate handbook(s) by a neonatologist. Interviews were transcribed verbatim and thematic analysis of the data was completed. Eleven parents were interviewed. All parents described the provision of the handbook(s) following the consultation with a neonatologist as the ideal time. All parents considered a visual representation of the data to be invaluable. Parents considered the handbooks easy to understand and straightforward. Some parents were satisfied with simple information, which helped them feel less overwhelmed; others felt the depth of information was insufficient. Parents preferred a paper copy to electronic. Reactions to the photo of an infant receiving intensive care varied; some parents felt frightened, others felt comforted. Overall, parents positively evaluated the handbooks, supporting their utility for parents anticipating extremely preterm birth. Concrete suggestions for improvement were made; the handbooks will be modified accordingly. Parents at other perinatal centers may benefit from receiving such handbooks.
Elective cesarean delivery and long-term cardiovascular morbidity in the offspring – a population-based cohort analysis
Creators: name: Galin, Shaked
name: Wainstock, Tamar
name: Sheiner, Eyal
name: Landau, Daniella
name: Walfisch, Asnat
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: To evaluate the impact of cesarean delivery (CD) on offspring risk for long-term cardiovascular morbidity. A population-based cohort analysis was performed, including all singleton term deliveries occurring between 1991 and 2014 at a single tertiary medical center. A comparison was performed between children delivered via CD and those delivered vaginally. Fetuses with cardiac or other congenital malformations were excluded, as were cases of urgent CD and pregnancies involving preeclampsia, gestational diabetes, placenta previa, labor induction, fetal growth restriction, preterm PROM, and instrumental deliveries. Hospitalizations of the offspring up to 18 years of age involving cardiovascular morbidity were compared between the two study groups. A Kaplan–Meier survival curve compared cumulative cardiovascular morbidity incidence and a Cox regression model controlled for confounders. Of the 132,054 term deliveries who met the inclusion criteria; 8.9% were CDs (n = 11,746) and 91.1% (n = 120,308) were vaginal deliveries. Cardiovascular hospitalization incidence per 1000 person follow up years was 0.742 in the CD group and 0.054 in the comparison group (HR = 1.3, 95%CI 1.051–1.710, p = .018). The Kaplan–Meier survival curve demonstrated a significantly higher cumulative incidence of cardiovascular morbidity following CD (log rank p = .018). In the Cox proportional hazards model, CD was noted as an independent risk factor for offspring long-term pediatric cardiovascular morbidity (adjusted HR = 1.295, CI 1.005–1.668, p = .04) when controlling for maternal age, obesity, ethnicity, gestational age, newborn gender, low birthweight, maternal preexisting cardiovascular disease, and deliveries occurring after 2008. Singletons delivered by CD at term have an increased risk of long-term cardiovascular morbidity.
The Circulating Library in Melbourne: its place in the book-trade and its influence on readers.
Creators: name: PEREYRA, PETER RUSSELL
Publisher: name: Monash University
Year: 2022
Subjects: classificationCode: 470514
subject: Literary theory

description: Circulating libraries were small businesses that loaned books for a fee. The majority of the public had little access to affordable books, so the circulating libraries—although few in number in the nineteenth century—began to increase considerably from the 1920s when genre fiction became increasingly popular. Their number peaked in 1940 with over four hundred libraires in operation that loaned more than ten million books each year. This thesis examines the locations and operations of the circulating libraries throughout Melbourne, until the mid-1960s, when the rate supported council libraries provided free loans and assisted in the demise of the commercial library.
Vertical transmission of SARS CoV-2: a systematic review
Creators: name: Deniz, Melis
name: Tezer, Hasan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The aim of this study is to review the current evidence on the vertical transmission of SARS CoV-2. Combination of the following keywords; COVID-19, SARS CoV-2, placenta, vertical transmission, intrauterine infection, breast milk were searched in databases. In the 50 studies included, 17 newborns testing positive for SARS CoV-2 by RT-PCR were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated. Eight placental tissues testing positive for the virus were reported. Three positive RT-PCR results of test of breast milk have been reported recently. One amniotic fluid testing positive was reported. Possible vertical transmission of SARS CoV-2 has been observed in some studies currently. More RT-PCR tests on amniotic fluid, placenta, breast milk and cord blood are required.
Additional file 1 of Chromatographic fingerprinting of ipratropium and fenoterol in their novel co-formulated inhaler treating major respiratory disorders; application to delivered dose uniformity testing along with greenness and whiteness assessment
Creators: name: Ali, Salma N.
name: Saad, Samah S.
name: Fayed, Ahmed S.
name: Marzouk, Hoda M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Supplementary Material 1
Supplementary document for Controlling directional excitation of surface plasmon polaritons by tunable non-Hermitian metasurfaces - 6541884.pdf
Creators: name: Guohao, Zhang
name: Liu, Jiaqing
name: Dong, Daxing
name: Chen, Changdong
name: Liu, Youwen
name: Fu, Yangyang
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: detailed calculations and simulations
UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1
Creators: name: Herlihy, Anna E
name: Boeing, Stefan
name: Weems, Juston C
name: Walker, Jane
name: Dirac-Svejstrup, A Barbara
name: Lehner, Michelle Harreman
name: Conaway, Ronald C
name: Conaway, Joan W
name: Svejstrup, Jesper Q
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: Model organisms
Biochemistry & Proteomics
Tumour Biology
Gene Expression
Genetics & Genomics
Genome Integrity & Repair
Chemical Biology & High Throughput
Computational & Systems Biology

description: During transcription, RNA polymerase II (RNAPII) faces numerous obstacles, including DNA damage, which can lead to stalling or arrest. One mechanism to contend with this situation is ubiquitylation and degradation of the largest RNAPII subunit, RPB1 - the ‘last resort’ pathway. This conserved, multi-step pathway was first identified in yeast, and the functional human orthologues of all but one protein, RNAPII Degradation Factor 1 (Def1), have been discovered. Here we show that following UV-irradiation, human Ubiquitin-associated protein 2 (UBAP2) or its paralogue UBAP2-like (UBAP2L) are involved in the ubiquitylation and degradation of RNAPII through the recruitment of Elongin-Cul5 ubiquitin ligase. Together, our data indicate that UBAP2 and UBAP2L are the human orthologues of yeast Def1, and so identify the key missing proteins in the human last resort pathway.
KIBER XAVFSIZLIK: GLOBAL TAHDIDLAR VA MILLIY HIMOYA
Creators: name: Oʻzbekiston xalqaro islom akademiyasi Islom Iqtisodiyoti va xalqaro munosabatlar fakulteti Axborot xavfsizligi taʼlim yoʻnalishi 1-bosqich talabasi Xasanov Jasur Muxammadi oʻgʻli
Publisher: name: Zenodo
Year: 2024

description: Zamonaviy texnologiyalar hayotimizning ajralmas qismiga aylanib, bizning shaxsiy va ish hayotimizga chuqur kirib kelmoqda. Biroq, bu yangi imkoniyatlar bilan birga, kiber jinoiyatchilik kabi yangi xavflar ham paydo bo’lmoqda. Ushbu maqola, raqamli dunyoda xavfsizlikni ta’minlashning muhimligini va kiber jinoiyatchilikka qarshi kurashishda samarali strategiyalarni muhokama qiladi. Maqola, kiber hujumlarning turli shakllari va ularning jamiyatimizga ta’sirini tahlil qilish bilan boshlanadi. Keyin, kiber xavfsizlikning eng yaxshi amaliyotlari va korporativ hamda shaxsiy darajada qo’llanilishi mumkin bo’lgan himoya choralari haqida gapiriladi. Shuningdek, maqola, kiber xavfsizlik sohasidagi eng so’nggi rivojlanishlar va texnologiyalarni, jumladan sun’iy idrok va avtomatlashtirishni qamrab oladi. Nihoyat, “Raqamli Dunyoda Xavfsizlik” maqolasi, o’quvchilarga kiber tahdidlarni anglash va ularning oldini olish uchun zarur bilim va vositalarni taqdim etishga intiladi. Bu bilan, har bir foydalanuvchi o’zining raqamli izini himoya qilish va kiber jinoiyatchilikka qarshi turish uchun zarur choralar ko’rishga tayyor bo’ladi.

Kalit soʻzlar:Kiber xavfsizlik, Raqamli himoya, Kiber jinoiyatchilik, Ma’lumotlarni himoyalash, Shaxsiy maxfiylik, Kiber hujumlar, Zararli dasturlar, Tarmoq xavfsizligi, Sun’iy idrok, Avtomatlashtirish
Additional file 1 of A metabolite-based liquid biopsy for detection of ovarian cancer
Creators: name: Fahrmann, Johannes F.
name: Ghasemi, Seyyed Mahmood
name: Han, Chae Y.
name: Wu, Ranran
name: Dennison, Jennifer B.
name: Vykoukal, Jody
name: Celestino, Joseph
name: Lu, Karen
name: Lu, Zhen
name: Drescher, Charles
name: Do, Kim-Anh
name: Hanash, Samir
name: Bast, Robert C.
name: Irajizad, Ehsan
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Supplementary Material 1.
Supplementary Tables S1-S4 from Evaluating the neuropeptide-social cognition link in ageing: the mediating role of basic cognitive skills
Creators: name: Polk, Rebecca
name: Horta, Marilyn
name: Lin, Tian
name: Porges, Eric
name: Ojeda, Marite
name: Nazarloo, Hans P.
name: Carter, C. Sue
name: Ebner, Natalie C.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: The roles of oxytocin (OT) and arginine-vasopressin (AVP) as crucial modulators of social cognition and related behaviours have been extensively addressed in the literature. The involvement of these neuropeptides in social cognition in ageing, however, and a potential mediating effect of basic cognitive capacities on this link, are not well understood. To fill these research gaps, this study assessed associations of plasma OT and AVP levels with dynamic emotion identification accuracy in generally healthy older men (aged 55–95 years) and probed the underlying roles of crystallized and fluid cognition in these associations. Higher plasma OT levels were associated with lower accuracy in dynamic emotion identification, with this negative relationship fully mediated by cognition. For plasma AVP levels, in contrast, there was no association with dynamic emotion identification accuracy. Integrated within existing theoretical accounts, results from this study advance understanding of the neuropeptide-social cognition link in ageing and support basic cognitive capacities as mediators in this association.This article is part of the theme issue ‘Interplays between oxytocin and other neuromodulators in shaping complex social behaviours’.
Artifact for "POPACheck: A Model Checker for Probabilistic Pushdown Automata"
Creators: name: Pontiggia, Francesco
name: Bartocci, Ezio
name: Chiari, Michele
Publisher: name: Zenodo
Year: 2025

description: Artifact for tool paper "POPACheck: A Model Checker for Probabilistic Pushdown Automata"  (v2).

Conditionally accepted at CAV'25.

This artifact contains the source code of POPACheck used in the experimental evaluation of the paper, as well as a virtual machine equipped with scripts and instructions on how to replicate automatically the experimental evaluation. Please refer to README.md.
Artifact for "POPACheck: A Model Checker for Probabilistic Pushdown Automata"
Creators: name: Pontiggia, Francesco
name: Bartocci, Ezio
name: Chiari, Michele
Publisher: name: Zenodo
Year: 2025

description: Artifact for tool paper "POPACheck: A Model Checker for Probabilistic Pushdown Automata".

Conditionally accepted at CAV'25.

This artifact contains the source code of POPACheck used in the experimental evaluation of the paper, as well as a virtual machine equipped with scripts and instructions on how to replicate automatically the experimental evaluation. Please refer to README.md.
Online adaptation of the search process of meta-heuristic algorithms
Creators: name: Carvalho, João
name: Pinto, Tiago
name: Romero, Ruben
Publisher: name: Zenodo
Year: 2022

description: Abstract for the Workshop on Artificial Intelligence Techniques for the Optimization of Electric Power Distribution Systems
description: Project funding: Fundação para a Ciência e a Tecnologia with grant: FCT/CAPES 2019.00141.CBM
Recent Archaeological Discoveries in Villupuram District, Tamiinadu, India
Creators: name: International Journal of Indian Science and Research
Publisher: name: International Journal of Indian Science and Research
Year: 2024
Subjects: Villupuram District, Iron Age, Archaeology, tradition, Pallava

description: Archaeology and the cultural heritage of our forefathers were unique and outstanding.  As per the Archaeological sources, Villupuram district is considered to be an ancient place.  This recent archaeological discoveries in Villupuram district is very much essential for the reconstruction and restructuring of the history of Villupuram district. This research aptly discusses the great phenomenon of recent archaeological discoveries made by the exploration of new findings by the present research scholar.  The archaeological vestiges in the form of pre-historic tools of Paleolithic, Mesolithic, Neolithic ages besides the occurrence of rock paintings, Iron Age burials and habitation sites exemplify the human activity of the contemporary period.  With this gamut of archaeological finds of the district, one can visualize the social scenario that Villupuram passed through the ages and the same could be the pride of the current as well as the future generation in creating an eco-friendly environ promoting tourism, culture, and tradition.  Villupuram district is not only special on the Archaeological basis.  From this archaeological discoveries research, one fact is quite obvious that the District of Villupuram has always played a significant role in the annals of Tamilnadu from the days immemorial.