cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Enhancing Multifunctionalities of Transition Metal Dichalcogenide Monolayers via Intercalation of Molecules and Ions
Creators: name: Yu, Yifei
name: Huang, Lujun
name: Li, Guoqing
name: Barrette, Andrew
name: Cai, Yong-Qing
name: Yu, Yiling
name: Gundogdu, Kenan
name: Zhang, Yong-Wei
name: Cao, Linyou
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Transition metal dichalcogenide (TMDC) monolayers present a remarkable multifunctional material with potential to enable the development of a wide range of novel devices. However, the functionalities observed often fall short of the expectation, which hinders the device development. Here we demonstrate that the optical, catalytic, and thermal functionalities of TMDC monolayers can all be substantially enhanced by up to orders of magnitude with the intercalation of water molecules or small cations (H+ and Li+) between the monolayers and underlying substrates. In contrast, the same molecules or cations adsorbed on top of the monolayers show negligible effects. We also discover two major roles of the intercalated species in the enhancement: doping the monolayers and modifying the interaction of the monolayers with the substrate. The result points out a versatile and convenient strategy of using the intercalation of molecules or ions to enhance the functionalities of TMDC monolayers.
description: This paper has been withdrawn due to the incomplete introduction information and reference
Real-time monitoring of solid-phase peptide synthesis using a variable bed flow reactor
Creators: name: Sletten, Eric T.
name: Nuño, Manuel
name: Guthrie, Duncan
name: Seeberger, Peter H.
Publisher: name: Freie Universität Berlin
Year: 2019
Subjects: subject: solid-phase peptidesynthesis
subject: bed flow reactor
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: On-resin aggregation and incomplete amide bond formation are major challenges for solid-phase peptide synthesis that are difficult to be monitored in real-time. Incorporation of a pressure-based variable bed flow reactor into an automated solid-phase peptide synthesizer permitted real-time monitoring of resin swelling to determine amino acid coupling efficiency and on-resin aggregation.
Strong Clustering of Lyman Break Galaxies around Luminous Quasars at z~4
Creators: name: Garcia-Vergara, Cristina
name: Hennawi, Joseph F.
name: Barrientos, L. Felipe
name: Rix, Hans-Walter
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In the standard picture of structure formation, the first massive galaxies are expected to form at the highest peaks of the density field, which constitute the cores of massive proto-clusters. Luminous quasars (QSOs) at z~4 are the most strongly clustered population known, and should thus reside in massive dark matter halos surrounded by large overdensities of galaxies, implying a strong QSO-galaxy cross-correlation function. We observed six z~4 QSO fields with VLT/FORS exploiting a novel set of narrow band filters custom designed to select Lyman Break Galaxies (LBGs) in a thin redshift slice of Delta_z~0.3, mitigating the projection effects that have limited the sensitivity of previous searches for galaxies around z>~4 QSOs. We find that LBGs are strongly clustered around QSOs, and present the first measurement of the QSO-LBG cross-correlation function at z~4, on scales of 0.110^12 M_sun) dark matter halos at z~4.
description: 25 pages, 22 figures, submitted to the ApJ
MOESM2 of Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes
Creators: name: Strouhal, Michal
name: Oppelt, Jan
name: Mikalová, Lenka
name: Arora, Natasha
name: Nieselt, Kay
name: González-Candelas, Fernando
name: Šmajs, David
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Mapping statistics of input read pairs mapped to the reference genomes. Sequencing reads derived from the Chinese strain SRA data were mapped to the Treponema pallidum subsp. pallidum (TPA) SS14 and Nichols reference genomes [6] and to the rabbit genome (Statistics was calculated from post-processed mappings; repetitive and homologous sequences and PCR duplicated reads were excluded from the statistics).
Prizing the popular: Steven Spielberg and style by stealth
Creators: name: Mairata, James
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: During his career, Steven Spielberg has both created and facilitated the creation of a remarkable quantity and range of popular entertainment. With two of the films he has directed in the top ten all-time box office revenue list and seven in the top one hundred, his popular success as a director of narrative cinema remains unrivalled in Hollywood and possibly in the world. Spielberg is clearly very good at recognising and telling stories that appeal to a wide audience. Critics and scholars have written extensively on the thematic, semantic and symptomatic aspects of his films but little analysis has been devoted to examining how he constructs narrative - how he makes use of style and its role in enhancing the popularity of his films. This thesis argues that Spielberg utilises stylistic strategies that are both unique and innovative when considered within the context of the classical Hollywood system. I identify two distinct systems at work in Spielberg’s application of style. One is the use of deep space compositions and staging, a form that was commonly seen in Hollywood cinema until the rise of the “New Hollywood” in the early 1970s. The other system is based on the ubiquitous shot, reverse shot arrangement most commonly used for dialogue scenes, and which Spielberg has modified into what I label as wide reverses. Through the integration of both systems, Spielberg is able to create a more “complete” visual sense of scenographic space and a more comprehensive world of the narrative, while still remaining within the conventional boundaries of classical style. The wide reverse system also permits him to present a more highly developed version of Hollywood’s conventional practice of rendering style as transparent or unnoticed. This, together with the wide reverse further enables Spielberg to create a narrative that offers the spectator both a more immersive and more affective experience.
title: ADCO, Premier cartulaire de l'abbaye de Molesmes (XIIe siècle), Cart. 142 (7 H 6), 128 pages, f. 0038v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Premier cartulaire de l'abbaye de Molesmes (XIIe siècle), Archives départementales de la Côte-d'Or, Cart. 142 (7 H 6), 128 pages, f. 0038v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Premier cartulaire de l'abbaye de Molesmes (XIIe siècle), Archives départementales de la Côte-d'Or, Cart. 142 (7 H 6), 128 pages, f. 0038v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb137389344
description: Provenance: abbaye de Molesme
description: Provenance: http://www.wikidata.org/entity/Q334044
title: Around-Body Interaction: Leveraging Limb Movements for Interacting in a Digitally Augmented Physical World
Creators: name: Müller, Florian
Publisher: name: UNSPECIFIED
Year: 2020

description: Recent technological advances have made head-mounted displays (HMDs) smaller and untethered, fostering the vision of ubiquitous interaction with information in a digitally augmented physical world. For interacting with such devices, three main types of input - besides not very intuitive finger gestures - have emerged so far: 1) Touch input on the frame of the devices or 2) on accessories (controller) as well as 3) voice input. While these techniques have both advantages and disadvantages depending on the current situation of the user, they largely ignore the skills and dexterity that we show when interacting with the real world: Throughout our lives, we have trained extensively to use our limbs to interact with and manipulate the physical world around us. This thesis explores how the skills and dexterity of our upper and lower limbs, acquired and trained in interacting with the real world, can be transferred to the interaction with HMDs. Thus, this thesis develops the vision of around-body interaction, in which we use the space around our body, defined by the reach of our limbs, for fast, accurate, and enjoyable interaction with such devices. This work contributes four interaction techniques, two for the upper limbs and two for the lower limbs: The first contribution shows how the proximity between our head and hand can be used to interact with HMDs. The second contribution extends the interaction with the upper limbs to multiple users and illustrates how the registration of augmented information in the real world can support cooperative use cases. The third contribution shifts the focus to the lower limbs and discusses how foot taps can be leveraged as an input modality for HMDs. The fourth contribution presents how lateral shifts of the walking path can be exploited for mobile and hands-free interaction with HMDs while walking.
Additional file 6: Table S6. of Pangenome analyses of the wheat pathogen Zymoseptoria tritici reveal the structural basis of a highly plastic eukaryotic genome
Creators: name: ClĂŠmence Plissonneau
name: Hartmann, Fanny
name: Croll, Daniel
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Analyses of genes identified in the isolate IPO323 and classified as accessory or singleton genes in the pangenome. (PDF 67Â kb)
THE IMPACT OF SOFT SKILLS DEFICIENCY IN UNIVERSITY EDUCATION  ON UNEMPLOYMENT RATES IN UZBEKISTAN
Creators: name: 1Iroda Akhmadova
name: Azizbek Mamarazzoqov
name: Muhammadfozilxon Valikhonov
name: Sarvar Nuriddinov
Publisher: name: Zenodo
Year: 2024

description: Through our written article, we researched that the lack of soft skills among university students is one of the reasons for its impact on the unemployment rate. Through this, we determined the state of knowledge of soft skills among university students, their importance for getting a job, and thus Together with the employee of the HR department of a real company, we studied the soft skills that students lack when starting a job, and those that are required during work. Through this, we made recommendations on the soft skills that university students should learn at the university with two types of research, and on the soft skills that are important for their development and employment.
title: Some Effects of the Polychaete Nereis Succinea Frey and Leukart 1847 on the Distribution of Copper Cadmium and Zinc in Sediments and Water
Creators: name: August, Gabriela Kitzig
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1982

description: Two laboratory experiments, each lasting 216 hours, were conducted in order to determine the effects of a burrowing polychaete, Nereis succinea Frey and Leukart, 1847, on the distribution of copper, cadmium, and zinc in sediments and water in environmentally controlled microcosms. Dissolved metal concentrations in microcosms containing worms (experimental) decreased more rapidly than in microcosms without worms (controls). From 72 hours to 216 hours, suspended metal concentrations in experimental microcosms increased while concentrations in controls remained relatively constant. Sediment cadmium concentrations in experimental microcosms increased more over time than in controls. Polychaetes accumulated significant amounts of all three metals. These observations indicated that N. succinea initially enhances the removal of metals from the water column to sediments, but later causes some resuspension of metals. Bioaccumulation by N. succinea could result in the incorporation of metals into the food chain.
Additional file 1: of Clinical research ethics review process in Lebanon: efficiency and functions of research ethics committees â results from a descriptive questionnaire-based study
Creators: name: Atallah, David
name: Moubarak, Malak
name: Kassis, Nadine El
name: Abboud, Sara
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Study Questionnaire - RECs in Lebanon. (DOCX 54 kb)
MOESM1 of Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes
Creators: name: Strouhal, Michal
name: Oppelt, Jan
name: Mikalová, Lenka
name: Arora, Natasha
name: Nieselt, Kay
name: González-Candelas, Fernando
name: Šmajs, David
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1. Data analysis and methods used in the reanalysis of Chinese Treponema pallidum samples.
Chemoradiotherapy plus hyperthermia (CRTH) versus chemoradiotherapy (CRT) alone in neoadjuvant treatment of soft tissue sarcoma: tumor response, treatment toxicity and disease control
Creators: name: Willner, Alexander
name: Agaimy, Abbas
name: Fechner, Katja
name: Ott, Oliver
name: Denz, Axel
name: Weissmann, Thomas
name: Meidenbauer, Norbert
name: Höfler, Daniel
name: Gaipl, Udo
name: Frey, Benjamin
name: Schmidt, Manfred
name: Haller, Florian
name: Horch, Raymund
name: Hartmann, Arndt
name: Grützmann, Robert
name: Fietkau, Rainer
name: Semrau, Sabine
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Cancer

description: Neoadjuvant chemotherapy and radiotherapy for the management of soft tissue sarcomas (STS) are still preferably delivered sequentially, with or without concurrent hyperthermia. Concurrent delivery of chemo-, radio- and thermotherapy may produce synergistic effects and reduce chemotherapy-free intervals. The few available studies suggest that concurrent chemoradiation (CRT) has a greater local effect. Data on the efficacy and toxicity of adding hyperthermia to CRT (CRTH) are sparse. A cohort of 101 patients with STS of the extremities and trunk who received CRT (n = 33) or CRTH (n = 68) before resection of macroscopic tumor (CRT: n = 19, CRTH: n = 49) or re-resection following a non-oncological resection, so called ‘whoops procedure’, (CRT: n = 14, CRTH: n = 19) were included in this retrospective study. CRT consisted of two cycles of doxorubicine (50 mg/m2 on d2) plus ifosfamide (1500 mg/m2 on d1-5, q28) plus radiation doses of up to 60 Gy. Hyperthermia was delivered in two sessions per week. All patients received the minimum dose of 50 Gy. Median doses of ifosfamide and doxorubicin were comparable between CRT (75%/95%) and CRTH (78%/97%). The median number of hyperthermia sessions was seven. There were no differences in acute toxicities. Major wound complications occurred in 15% (CRT) vs. 25% (CRTH) (p = 0.19). In patients with macroscopic disease, the addition of hyperthermia resulted in a tendency toward improved remission: regression ≥90% occurred in 21/48 (CRTH) vs. 4/18 (CRT) patients (p = 0.197). With a median postoperative follow-up of 72 months, 6-year local control and overall survival rates for CRTH vs. CRT alone were 85 vs. 78% (p = 0.938) and 79 vs. 71% (p = 0.215). Both CRT and CRTH are well tolerated with an expected rate of wound complications. The results suggest that adding hyperthermia may improve tumor response.
D4.1 Experimentation Tools and VNF Repository
Creators: name: Landi, Giada
name: Brenes, Juan
name: Bernini, Giacomo
name: Giar-Dina, Pietro
name: Femminella, Mauro
name: Giaccone, Paolo
name: Pergolesi, Matteo
name: Reali, Gianluca
name: Jaime Garcia-Reinoso,
name: Cominardi, Luca
name: Guimaraes, Carlos
name: Serrano, Pablo
name: Almodovar, Jonathan
name: Jordan, Cristina Quintana
name: Ramón Pérez,
name: Zabala, Aitor
name: Suraci, Vincenzo
name: Canale, Silvia
name: Chianese, Yuri Maria
name: Gra-Ziano Ciucciarelli,
name: Corsaletti, Gerardo
name: Biscuola, Oriano
name: K. Trichias
name: P. Demestichas
name: K. Tsagkaris
name: G. Loukas
name: V. Stavroulaki,
name: D. Meridou
name: O. Zekai
name: E. Kostara
Publisher: name: Zenodo
Year: 2019

description: This deliverable provides a first release of the 5G EVE portal tools for the design, specification, management and monitoring of experiments that verticals can execute over the 5G EVE platform to validate the behaviour and performance of their services in realistic 5G environments. The deliverable consists of two major compo-nents: (i) this document, which describes the concepts around 5G EVE experiments, providing also details about some of the portal components in support of them, and (ii) a number of software tools that help the 5G EVE experimenters in the different phases of the experiment definition, execution, and validation.
 The document introduces 5G EVE experiments, identifying their phases (from the initial design, up to the exe-cution and validation steps) and roles of the different 5G EVE actors during a 5G EVE experiment typical lifecycle. Focus is on the different actions that can be performed through 5G EVE Portal, which provides a unified access to all 5G EVE services, across the entire multi-site platform. The expected interactions between 5G EVE actors and 5G EVE platform, through the Portal, are presented in detail for each experiment phase. Moreover, the deliverable reports also the design of the internal workflows regulating the communications among the functional components of the portal and the interactions with the other entities of the 5G EVE plat-form.
 The deliverable provides also the description and the documentation for the experimentation tools in the scope of the Task T4.1 and Task T4.4 activities. In particular, this deliverable covers the following components: (i) the tools for experiment monitoring and results collection and storage; (ii) browse and look-up tools and (iii) the intent-based interface in support of experiment definition; (iv) the trouble ticketing tool to help experiment-ers and facilitate their interaction with the dedicated 5G EVE support teams; and (v) the VNF catalogue storing 5G EVE offerings, in terms of blueprints and descriptors of services and experiments. Some of these compo-nents are based on widely used open source software, which have been customized and configured to meet the specific requirements of the 5G EVE platform. Others have been developed in the context of the project reusing and extending, where possible, software prototypes resulting from previous phase 1 and phase 2 projects.
The effects of a single and a series of Finnish sauna sessions on the immune response and HSP-70 levels in trained and untrained men
Creators: name: Pilch, Wanda
name: Szarek, Marta
name: Olga, Czerwińska-Ledwig
name: Anna, Piotrowska
name: Żychowska, Małgorzata
name: Ewa, Sadowska-Krepa
name: Andraščíková, Štefánia
name: Pałka, Tomasz
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The aim of the study was to investigate the effect of a Finnish sauna on the immune status parameters. The hypothesis was that hyperthermia would improve immune system’s functioning by changing the proportion of lymphocyte subpopulations and would activate heat shock proteins. We assumed that the responses of trained and untrained subjects would be different. Healthy men (20–25 years old) were divided into groups: the trained (T; n = 10), and the untrained group (U; n = 10). All participants were subjected to 10 baths (each one consisted of: 3 × 15-minute exposure with cooled down for 2 min. Body composition, anthropometric measurements, VO2 peak were measured before 1st sauna bath. Blood was collected before the 1st and 10th sauna bath, and 10 min after their completion to asses an acute and a chronic effect. Body mass, rectal temperature and heart rate (HR) were assessed in the same time points. The serum levels of cortisol, Il-6, HSP70 were measured with use of ELISA method, IgA, IgG and IgM by turbidimetry. White blood cells (WBC), leukocyte populations counts: neutrophils, lymphocytes, eosinophils, monocytes, and basophils were determined with use of flow cytometry as well as T-cell subpopulations. No differences were found in the increase in rectal temperature, cortisol and immunoglobulins between groups. In response to the 1st sauna bath, a greater increase in HR was observed in the U group. After the last one, the HR value was lower in the T group. The impact of sauna baths on WBC, CD56+, CD3+, CD8+, IgA, IgG and IgM was different in trained and untrained subjects’ responses. A positive correlation between the increase in cortisol concentrations and increase in internal temperatures after the 1st sauna was found in the T (r = 0.72) and U group (r = 0.77), between the increase in IL-6 and cortisol concentrations in the T group after the 1st treatment (r = 0.64), between the increase in IL-10 concentration and internal temperature (r = 0.75) and between the increase in IL-6 and IL-10 (r = 0.69) concentrations, also. Sauna bathing can be a way to improve the immune response, but only when it is undertaken as a series of treatments.
HYPER: pre-clinical device for spatially-confined magnetic particle hyperthermia
Creators: name: Carlton, Hayden
name: Weber, Matthias
name: Peters, Maximilian
name: Arepally, Nageshwar
name: Lad, Yash Sharad
name: Jaswal, Anshul
name: Ivkov, Robert
name: Attaluri, Anilchandra
name: Goodwill, Patrick
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Magnetic particle hyperthermia is an approved cancer treatment that harnesses thermal energy generated by magnetic nanoparticles when they are exposed to an alternating magnetic field (AMF). Thermal stress is either directly cytotoxic or increases the susceptibility of cancer cells to standard therapies, such as radiation. As with other thermal therapies, the challenge with nanoparticle hyperthermia is controlling energy delivery. Here, we describe the design and implementation of a prototype pre-clinical device, called HYPER, that achieves spatially confined nanoparticle heating within a user-selected volume and location. Spatial control of nanoparticle heating was achieved by placing an AMF generating coil (340 kHz, 0–15 mT), between two opposing permanent magnets. The relative positions between the magnets determined the magnetic field gradient (0.7 T/m–2.3 T/m), which in turn governed the volume of the field free region (FFR) between them (0.8–35 cm3). Both the gradient value and position of the FFR within the AMF ([−14, 14]x, [−18, 18]y, [−30, 30]z) mm are values selected by the user via the graphical user interface (GUI). The software then controls linear actuators that move the static magnets to adjust the position of the FFR in 3D space based on user input. Within the FFR, the nanoparticles generate hysteresis heating; however, outside the FFR where the static field is non-negligible, the nanoparticles are unable to generate hysteresis loss power. We verified the performance of the HYPER to design specifications by independently heating two nanoparticle-rich areas of a phantom placed within the volume occupied by the AMF heating coil.
HMGB1 released from dead tumor cells after insufficient radiofrequency ablation promotes progression of HCC residual tumor via ERK1/2 pathway
Creators: name: Zhou, Yingshi
name: Liu, Xiaodi
name: Zhang, Wenyue
name: Xu, Yanni
name: Zhang, Qi
name: Xiong, Shiyu
name: Tang, Haifeng
name: Luo, Baoming
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Radiofrequency ablation (RFA) is a first-line treatment for early-stage hepatocellular carcinoma (HCC). However, the recurrence after RFA remains an urgent challenge. Current studies have shown that residual tumor after RFA is an important cause of recurrence. We hypothesized that the products of dead tumor cells after RFA have direct effects on the development of residual tumors. Further, we investigated the underlying mechanisms. The proliferation and invasion ability of HepG2 and Huh7 cells were assessed using CCK-8, colony formation, EdU, transwell invasion and migration assay. Immunofluorescence and western blotting were used to show HMGB1 released from dead tumor cells. The levels of MMP2, MMP9, CyclinE1 and pERK1/2 were determined using western blotting. Finally, in vivo validation was performed in BALB/c nude mice xenograft tumor models. The products of dead tumor cells after thermal treatment can promote the proliferation and invasion of residual HCC cells. Dead tumor cells could release high-mobility group box 1 (HMGB1) after thermal treatment. Similar to the products of dead tumor cells, the recombinant protein of HMGB1 can promote the proliferation and invasion of residual HCC cells. Moreover, HMGB1 could bind to receptor of advanced glycation end-products. Then, it activated the ERK1/2 pathway and significantly upregulated the expressions of MMP2, MMP9, and CyclinE1. Our study reveals that HMGB1 released by dead tumor cells after thermal treatment can promote the proliferation and invasion of residual HCC cells. Hence, the HMGB1/RAGE/ERK1/2 pathway is a potential target for improving the prognosis of HCC after radiofrequency ablation.
A walk on the wild side: animal figures and the canon of proportion in Middle Kingdom wall scenes at Meir. Volume 1: Text
Creators: name: Leary, Nicolle
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This research will aim to shed new light on how the Egyptian artist represented animal figures at the Middle Kingdom site of Meir by examining and testing a convention known as the canon of proportion, which, thus far, has only been connected in detail with the representation of human figures. The animal figures under investigation are cattle, ducks and oryx, with the corpus numbering fifty eight subjects. The study has two major objectives: to gain an understanding of the canon of proportion in relation to animal figures at Meir through an examination of surviving grids along with the application of a hypothetical grid; and to track the development, purpose and continuity of the work processes used when rendering animal figures from the Old Kingdom to the Middle Kingdom. Based on the examination of existing and hypothetical grids and the identification of consistencies and variations in the horizontal and vertical rendering of animal figures, the study has been able to identify a proportional guide inplace at Meir. 'The study explores the historical and political contexts of the early Middle Kingdom, which appear to have influenced the proportional rendering of animal figures at Meir. These factors include the transmission of artistic models by means of travelling artists, the development of the canon of proportion and local traditions found within Egyptian provinces.
Additional file 5 of MetaGeneBank: a standardized database to study deep sequenced metagenomic data from human fecal specimen
Creators: name: Shao, Li
name: Liao, Jie
name: Qian, Jingyang
name: Chen, Wenbin
name: Fan, Xiaohui
Publisher: name: figshare
Year: 2021
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: Additional file 5 : Table S2. The candidate values for each parameter that can be used in searching.
Additional file 4: Table S2. of Overexpression of the proneural transcription factor ASCL1 in chronic lymphocytic leukemia with a t(12;14)(q23.2;q32.3)
Creators: name: Malli, Theodora
name: Rammer, Melanie
name: Haslinger, Sabrina
name: Burghofer, Jonathan
name: Burgstaller, Sonja
name: Hans-Christian Boesmueller
name: Marschon, Renate
name: Kranewitter, Wolfgang
name: Erdel, Martin
name: Deutschbauer, Sabine
name: Webersinke, Gerald
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: List of deregulated genes (Fold Change ≥2, FDR p ≤ 0.01). (DOCX 474 kb)
PVP with or without microwave ablation for the treatment of painful spinal metastases from NSCLC: a retrospective case-control study
Creators: name: Liu, Yiming
name: Yuan, Haoyue
name: Milan, Sigdel
name: Zhang, Chengzhi
name: Han, Xinwei
name: Jiao, Dechao
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: To compare the clinical efficacy of percutaneous vertebroplasty (PVP) alone and microwave ablation (MWA) combined with PVP for the treatment of painful spinal metastases from non-small cell lung cancer (NSCLC). From October 2014 to October 2021, the data of 58 NSCLC patients with refractory painful spinal metastases (visual analog scale score ≥ 5) were retrospectively collected and analyzed. Patients in Group A (n = 30) and Group B (n = 28) received PVP alone and MWA combined with PVP, respectively. The primary endpoint was pain relief. The secondary endpoints were quality of life (QoL), local tumor progression (LTP), and complications. The technical success rate was 100% in both groups. Patients in both groups showed similar pain relief at 1–12 weeks, but patients in Group B still showed sustained pain relief at 24 weeks compared to those in Group A (p = 0.03). The assessment of QoL showed similar changes. LTP (33.00% vs. 7.14%, p = 0.02) and cement leakage rates (40.00% vs. 7.14%, p = 0.03) were lower in Group B. The multivariate analysis demonstrated spinal metastases with a maximum diameter ≤ 3.0 cm (p = 0.027) and MWA combined with PVP (p = 0.028) were two independent protective factors for LTP. For cement leakage, spinal metastases with vertebral body compression (p = 0.019) was an independent risk factor, while MWA combined with PVP (p = 0.042) was an independent protective factor. MWA combined with PVP for painful spinal metastases from NSCLC performed more sustained pain relief (>6 months) and ultimately improved QoL with lower LTP and cement leakage rates, compared to PVP alone.
An Overview of Beginning Farms and Farmers
Creators: name: Key, Nigel
name: Lyons, Greg
name: Key, Nigel
name: Lyons, Greg
Publisher: name: Unknown
Year: 2019
Subjects: subject: Agricultural and Food Policy
subject: Agricultural Finance
subject: Farm Management
subject: Financial Economics
subject: Land Economics/Use
subject: Beginning farmers
subject: beginning ranchers
subject: Agricultural Resource Management Survey
subject: ARMS
subject: USDA programs
subject: farmland

description: Beginning farms (those on which all operators have no more than 10 years of farming experience) operate at a smaller scale, earn less farm income, and have more debt relative to their assets than more established farms. Beginning farm households work more off-farm and have less wealth than established farm households.
The grammar of mammalian brain capacity
Creators: name: Rodriguez, A
name: Granger, R
Publisher: name: arXiv
Year: 2016
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: Uniquely human abilities may arise from special-purpose brain circuitry, or from concerted general capacity increases due to our outsized brains. We forward a novel hypothesis of the relation between computational capacity and brain size, linking mathematical formalisms of grammars with the allometric increases in cortical-subcortical ratios that arise in large brains. In sum, i) thalamocortical loops compute formal grammars; ii) successive cortical regions describe grammar rewrite rules of increasing size; iii) cortical-subcortical ratios determine the quantity of stacks in single-stack pushdown grammars; iii) quantitative increase of stacks yields grammars with qualitatively increased computational power. We arrive at the specific conjecture that human brain capacity is equivalent to that of indexed grammars, far short of full Turing-computable (recursively enumerable) systems. The work provides a candidate explanatory account of a range of existing human and animal data, addressing longstanding questions of how repeated similar brain algorithms can be successfully applied to apparently dissimilar computational tasks (e.g., perceptual versus cognitive, phonological versus syntactic); and how quantitative increases to brains can confer qualitative changes to their computational repertoire.
description: 18 pages, 2 figures, 2 tables
Thermal ablation versus radiotherapy for inoperable stage III non-small cell lung cancer: a propensity score matching analysis
Creators: name: Yang, Wei-Yu
name: He, Yu
name: Peng, Muyun
name: Zhang, Zhe
name: Xie, Shouzhi
name: Wu, Zeyu
name: Hu, Qikang
name: Yu, Fenglei
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: To compare the survival benefits of thermal ablation (TA) and radiotherapy in inoperable patients with stage III non-small cell lung cancer (NSCLC). A retrospective analysis was conducted using the data from the Surveillance, Epidemiology, and End Results (SEER) program. Propensity score matching (PSM) was conducted to balance potential baseline confounding factors. Survival analyses were conducted using Kaplan–Meier and Cox regression methods. The present study included 33,393 inoperable patients with stage III NSCLC, including 106 patients treated with TA and 33,287 patients treated with radiotherapy. No statistical difference in overall survival (OS) (p = .065) or cancer-specific survival (CSS) (p = .996) was found between the patients treated with TA and those treated with radiotherapy. Using 1:3 matching, a matched cohort of 420 patients (105 patients treated with TA, 315 patients treated with radiotherapy) was identified. The differences in OS (p = .177) and CSS (p = .605) were still not significant between the radiotherapy and TA groups after PSM. According to subgroup analyses, TA showed comparable survival benefits in almost all subgroups compared to radiotherapy. For inoperable stage III NSCLC, the survival benefit of TA was comparable to radiotherapy. TA may be a potential therapeutic modality for inoperable stage III NSCLC.
Additional file 3: Figure S1. of Overexpression of the proneural transcription factor ASCL1 in chronic lymphocytic leukemia with a t(12;14)(q23.2;q32.3)
Creators: name: Malli, Theodora
name: Rammer, Melanie
name: Haslinger, Sabrina
name: Burghofer, Jonathan
name: Burgstaller, Sonja
name: Hans-Christian Boesmueller
name: Marschon, Renate
name: Kranewitter, Wolfgang
name: Erdel, Martin
name: Deutschbauer, Sabine
name: Webersinke, Gerald
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Hierarchical Clustering. (DOCX 115Â kb)
Additional file 6 of MetaGeneBank: a standardized database to study deep sequenced metagenomic data from human fecal specimen
Creators: name: Shao, Li
name: Liao, Jie
name: Qian, Jingyang
name: Chen, Wenbin
name: Fan, Xiaohui
Publisher: name: figshare
Year: 2021
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: Additional file 6 : Table S3. A document associating KO annotations with GO Terms.
Natural products from some filamentous fungi and other sources
Creators: name: Chaudhary, Nirmal Kumar
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Natural products remain a major source for new drugs and drug leads owing to their unparalleled structural and chemical diversity and "drug-likeness" because of their evolutionary optimization to interact with living systems, unlike synthetic libraries. However, a combination of tedious isolation, repetitive isolation of known compounds, poor yields (supply) and structural complexities hindering total synthesis are some major bottlenecks in the process of drug discovery and development from natural products. Microorganisms offer a relatively unexplored source of new natural products by virtue of their vast biodiversity that can address the supply issue through fermentation. Moreover, microorganisms are amenable to selection and genetic manipulation for overproduction of the desired metabolite(s). The primary aim of this thesis is the isolation, characterization and biological screening of the secondary metabolites of some filamentous fungal species. Secondary metabolites of three filamentous fungi - Aspergillus banksianus, Aspergillus luteorubrus and Talaromyces stipitatus were characterized and screened. A total of 15 polyketide derived natural products were isolated from A. banksianus of which 10 were new metabolites. Among these, were the first isochromanone-orsellinic acid conjugates, isochromanone-anthraquininone conjugateand sulphur containing isochromanones including a rare sulfoxide metabolite. Chemical investigation of A. luteorubrus resulted in six metabolites including two new molecules, one was known but is a new natural product. Talaromyces stipitatus led to the isolation of 21molecules among which nine were new molecules. Among the new metabolites of T.stipitatus were 5 natural talauxins, which are condensation products of duclauxin with various L-amino acids. The semi-synthesis of new analogues of talauxins derived from D- and L-amino acids (except proline) and duclauxin is described. In addition, four new molecules from an Australian rainforest tree Galbulimima baccata were isolated and characterized. The structures of the isolated compounds were established by 2D NMR spectroscopy. Absolute stereochemistry of the isolated compounds was determined based on optical rotations, ECD, NMR, molecular modelling and TDDFT calculations. Plausible biogenetic pathway leading to these secondary metabolites are proposed wherever possible which can help in the design of biomimetic synthesis of these compounds.
Custom Hypergraph Categories via Generalized Relations
Creators: name: Marsden, Dan
name: Genovese, Fabrizio
Publisher: name: arXiv
Year: 2017
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Category Theory (math.CT)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Process theories combine a graphical language for compositional reasoning with an underlying categorical semantics. They have been successfully applied to fields such as quantum computation, natural language processing, linear dynamical systems and network theory. When investigating a new application, the question arises of how to identify a suitable process theoretic model. We present a conceptually motivated parameterized framework for the construction of models for process theories. Our framework generalizes the notion of binary relation along four axes of variation, the truth values, a choice of algebraic structure, the ambient mathematical universe and the choice of proof relevance or provability. The resulting categories are preorder-enriched and provide analogues of relational converse and taking graphs of maps. Our constructions are functorial in the parameter choices, establishing mathematical connections between different application domains. We illustrate our techniques by constructing many existing models from the literature, and new models that open up ground for further development.
Lettre de Esprit-Claude-François Calvet à Jean-François Séguier, 1770-05-15
Creators: name: Calvet, Esprit-Claude-François
name: Esprit-Claude-François Calvet
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Antiquités (général)
Bibliographie
Botanique
Epigraphie
Sciences naturelles (général)
Collections

description: [personnes citées] Jacqueline Marie d' Urre, M. Alliès, Sebastiano Donati
description: [transcription] J'ai reçu, Monsieur et cher ami, le livre que vous m'avez renvoyé. J'aidu regret que vous ne l'ayez pas toujours gardé, vous savez bien que vous pouvez disposer de celui-là comme de tous ceux que j'ai.Il fallait du moins vous en servir jusqu'à ce que vous eussiez reçu le vôtre.

Le plâtre de Zénobie est tout prêt, je crois que vous le recevrez par la commodité d'un jeune homme nommé Alliès, qui va achever ses études à Montpellier. Si madame la comtesse d'Urre est à portée de s'en charger plutôt que lui, ce sera cette dame qui vous le portera.

Nous avons ici une grande quantité de jardiniers fleuristes, mais tous se bornent à vendre des fleurs et il n'y en a aucun qui, comme ceux de Bourgogne, vendent des griffes de renoncules ou des pates d'anémones.Il faut par conséquent des hasards pour en acquérir. Ne croyez pas pour cela que la commission que vous me donnez soit manquée, j'agirai ou je feraiagir auprès des personnes qui en ont, et je feraimon possible pour vous en procurer. On ne les tire de terre qu'après la pentecôte, j'attendrai ce temps pour en demander.

J'aiécrit depuis longtemps à M. Donati, et je luy ai fait vos compliments. Je souhaite pour le public et pour moique vous nous fassiezbientôt jouir de votre ouvrage sur les inscriptions antiques, [fol. 133v] mais je voudrais qu'il fut mieux imprimé qu'on n'imprime communément à Lucques, je trouve que les éditions de ce pays-là sont bien peu estimable.

Je vous remercie de ce que vous me marquez sur l'inscription de Néron, c`était là mon sentiment, je suis même surpris qu'elle ait puavoir des partisans.

Permettez que je vous consulte sur un monument dont je fis hier l'acquisition, il est de bronze, fort et pesant. Les lettres, les cercles et les ornements sont inscrustés d'argent, je vais en faire un dessin exact au bas de ma lettre, même grandeur, même épaisseur.

Je suis toujours avec le plus vif attachement

Monsieur

Votre très humble et très obéissant serviteur

Calvet

Il n'y a rien au revers [dessin]

Le bronze présente un air d'antiquité, on le prend d'abord pour un poids. Les lettres ne sont pas d'une belle forme, mais elles sont très éloignées du mauvais goût du bas empire.

[graduation] épaisseur

[fol. 134]

[fol. 134v]

D'Avignon

A Monsieur / Monsieur de Séguier / à Nîmes
description: [note autre main] Annotation de Jean-François Séguier, fol. 134 en face de du dessin de Calvet: «On doit lire C Triens, X Denarii, NI nummus unus, H Sestertius, nempe denarii quartapars.»
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 140, fol. 133-134v
description: Source: ark:/12148/btv1b10015185m
Additional file 1: Table S1. of Costs of potentially inappropriate medication use in residential aged care facilities
Creators: name: S. Harrison
name: L. Kouladjian OâDonnell
name: R. Milte
name: S. Dyer
name: E. Gnanamanickam
name: C. Bradley
name: E. Liu
name: S. Hilmer
name: M. Crotty
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Complete list of medications considered potentially inappropriate, according to the Beers Criteria, and adapted for an Australian setting. (DOCX 31Â kb)
MOESM1 of Gencore: an efficient tool to generate consensus reads for error suppressing and duplicate removing of NGS data
Creators: name: Chen, Shifu
name: Zhou, Yanqing
name: Chen, Yaru
name: Huang, Tanxiao
name: Liao, Wenting
name: Xu, Yun
name: Li, Zhicheng
name: Gu, Jia
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Additional file 1. Experiment Details