cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Caregiver-mediated interventions to support self-regulation among infants and young children (0-5 years): A realist review
Creators: name: Finlay-Jones, Amy
name: Bennett, Elaine
name: Downs, Jenny
name: Kendall, Sally
name: Kottampally, Keerthi
name: Lim, Yi
name: Mancini, Vincent
name: Marriott, Rhonda
name: Milroy, Helen
name: Robinson, Monique
name: Smith, Justin
name: Wakschlag, Lauren
name: Ohan, Jeneva
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: children
subject: infants
subject: mental health
subject: parenting
subject: realist review
subject: self-regulation

description: The aim of this realist review is to develop a programme theory of "what works" for caregiver-mediated interventions to support self-regulation in infants and young children (0-5 years). We will use a realist approach to synthesise data on the relationships between context, proposed mechanisms, and outcomes for experimental studies of caregiver-mediated interventions to support self-regulation in infants and young children. Data extracted from peer-reviewed literature will be integrated with insights from stakeholders, theoretical papers, and grey literature to develop and refine the programme theory.
Boosting the H2 Production Efficiency via Photocatalytic Organic Reforming: The Role of Additional Hole Scavenging System
Creators: name: AlSalka, Yamen
name: Al-Madanat, Osama
name: Hakki, Amer
name: Bahnemann, Detlef W.
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: Dual function photocatalysis
subject: Energy efficiency
subject: H2 production
subject: Oxalic acid
subject: Photocatalytic reforming
subject: TiO2
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The simultaneous photocatalytic H2 evolution with environmental remediation over sem-iconducting metal oxides is a fascinating process for sustainable fuel production. However, most of the previously reported photocatalytic reforming showed nonstoichiometric amounts of the evolved H2 when organic substrates were used. To explain the reasons for this phenomenon, a care-ful analysis of the products and intermediates in gas and aqueous phases upon the photocatalytic hydrogen evolution from oxalic acid using Pt/TiO2 was performed. A quadrupole mass spectrome-ter (QMS) was used for the continuous flow monitoring of the evolved gases, while high performance ion chromatography (HPIC), isotopic labeling, and electron paramagnetic resonance (EPR) were employed to understand the reactions in the solution. The entire consumption of oxalic acid led to a ~30% lower H2 amount than theoretically expected. Due to the contribution of the photo-Kolbe reaction mechanism, a tiny amount of formic acid was produced then disappeared shortly after the complete consumption of oxalic acid. Nevertheless, a much lower concentration of formic acid was generated compared to the nonstoichiometric difference between the formed H2 and the consumed oxalic acid. Isotopic labeling measurements showed that the evolved H2, HD, and/or D2 matched those of the solvent; however, using D2O decreased the reaction rate. Interestingly, the presence of KI as an additional hole scavenger with oxalic acid had a considerable impact on the reaction mechanism, and thus the hydrogen yield, as indicated by the QMS and the EPR measure-ments. The added KI promoted H2 evolution to reach the theoretically predictable amount and in-hibited the formation of intermediates without affecting the oxalic acid degradation rate. The pro-posed mechanism, by which KI boosts the photocatalytic performance, is of great importance in enhancing the overall energy efficiency for hydrogen production via photocatalytic organic reform-ing.
Equilibrium Surface Current and Role of U(1) Symmetry: sum rule and surface perturbations
Creators: name: Tada, Yasuhiro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We discuss effects of surface perturbations on equilibrium surface currents which contribute to orbital magnetization and orbital angular momentum in systems without time reversal symmetry. We show that, in a U(1) particle number conserving system, disorder and other perturbations at a surface do not affect the equilibrium surface current and corresponding orbital magnetization due to a sum rule which is analogous to Luttinger's theorem. On the other hand, for a superfluid, the sum rule is no longer applicable and hence the surface mass current and corresponding orbital angular momentum can depend on details of a surface.
description: 16 pages
What drives the dust activity of comet 67P/Churyumov-Gerasimenko?
Creators: name: Gundlach, B.
name: Blum, J.
name: Keller, H. U.
name: Skorov, Y. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We use the gravitational instability formation scenario of cometesimals to derive the aggregate size that can be released by the gas pressure from the nucleus of comet 67P/Churyumov-Gerasimenko for different heliocentric distances and different volatile ices. To derive the ejected aggregate sizes, we developed a model based on the assumption that the entire heat absorbed by the surface is consumed by the sublimation process of one volatile species. The calculations were performed for the three most prominent volatile materials in comets, namely, H_20 ice, CO_2 ice, and CO ice. We find that the size range of the dust aggregates able to escape from the nucleus into space widens when the comet approaches the Sun and narrows with increasing heliocentric distance, because the tensile strength of the aggregates decreases with increasing aggregate size. The activity of CO ice in comparison to H_20 ice is capable to detach aggregates smaller by approximately one order of magnitude from the surface. As a result of the higher sublimation rate of CO ice, larger aggregates are additionally able to escape from the gravity field of the nucleus. Our model can explain the large grains (ranging from 2 cm to 1 m in radius) in the inner coma of comet 67P/Churyumov-Gerasimenko that have been observed by the OSIRIS camera at heliocentric distances between 3.4 AU and 3.7 AU. Furthermore, the model predicts the release of decimeter-sized aggregates (trail particles) close to the heliocentric distance at which the gas-driven dust activity vanishes. However, the gas-driven dust activity cannot explain the presence of particles smaller than ~1 mm in the coma because the high tensile strength required to detach these particles from the surface cannot be provided by evaporation of volatile ices. These smaller particles can be produced for instance by spin-up and centrifugal mass loss of ejected larger aggregates.
Previous tonsillectomy modifies odds of tonsil and base of tongue cancer
Creators: name: Mazul, Angela L
name: Weissler, Mark C
name: Zevallos, Jose P.
name: Brennan, Paul
name: Anantharaman, Devasena
name: Abedi-Ardekani, Behnoush
name: Olshan, Andrew F
name: Rodriguez, Nidia
name: Neil Hayes,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: BACKGROUND: Tonsillectomy is a commonly performed surgical procedure that involves removal of the palatine tonsils. The purpose of this study is to examine the association between previous tonsillectomy and odds of oropharyngeal squamous cell carcinoma (OPSCC) in a large population-based case-control study. We hypothesise that previous tonsillectomy is associated with a decreased odds of tonsil cancer with no impact on the odds of developing base of tongue (BOT) cancer.

METHODS: This was a population-based, frequency-matched case-control study with multinomial logistic regression, including 1378 controls, 108 BOT cancer cases, and 198 tonsil cancer cases. Demographic and risk factor data were collected using a structured questionnaire during an in-home visit conducted by trained nurse-interviewers. The human papillomavirus (HPV) tumour status was determined through Luminex-based multiplex PCR and p16 status by immunohistochemistry.

RESULTS: Previous tonsillectomy was associated with a nearly two-fold increased odds of BOT cancer (OR=1.95, 95% CI 1.25-3.06, P=0.003) and a large decrease in the odds of tonsil cancer (OR=0.22, 95% CI 0.13-0.36, P<0.001). When HPV status was considered, tonsillectomy was associated with a decreased odds of HPV-positive tonsil cancer (OR=0.17, 95% CI 0.08-0.34, P<0.001) and an increased risk of HPV-positive BOT cancer (OR=2.46, 95% CI 1.22-4.95, P=0.012). When p16 status was considered, tonsillectomy was associated with an increased odds of p16-positive BOT cancer (OR=2.24, 95% CI 1.16-4.35, P=0.017) and a decreased odds of p16-positive tonsil cancer (OR=0.14, 95% CI 0.07-0.31, P<0.001).

CONCLUSIONS: Previous tonsillectomy modifies the odds of both tonsil and BOT cancer, with decreased odds of tonsil cancer and increased odds of BOT cancer. A history of previous tonsillectomy may play a role in OPSCC risk stratification when considered along with other covariates such as sexual history, smoking status, and age.
Improved thermoelectric properties in ceramic composites based on Ca3Co4O9 and Na2Ca2Nb4O13
Creators: name: Hinterding, R.
name: Wolf, M.
name: Jakob, M.
name: Oeckler, O.
name: Feldhoff, A.
Publisher: name: Amsterdam : Elsevier
Year: 2021
Subjects: subject: Calcium cobalt oxide
subject: Ceramic
subject: Composite
subject: Figure-of-merit
subject: Power factor
subject: Reaction sintering
subject: Sodium calcium niobate
subject: Thermoelectrics
subject: Dewey Decimal Classification::600 | Technik

description: The oxide materials Ca3Co4O9 and Na2Ca2Nb4O13 were combined in a new ceramic composite with promising synergistic thermoelectric properties. Both compounds show a plate-like crystal shape and similar aspect ratios but the matrix material Ca3Co4O9 with lateral sizes of less than 500 nm is about two orders of magnitude smaller. Uniaxial pressing of the mixed compound powders was used to produce porous ceramics after conventional sintering. Reactions between both compounds and their compositions were thoroughly investigated. In comparison to pure Ca3Co4O9, mixing with low amounts of Na2Ca2Nb4O13 proved to be beneficial for the overall thermoelectric properties. A maximum figure-of-merit of zT = 0.32 at 1073 K and therefore an improvement of about 19% was achieved by the ceramic composites.
Additive manufacturing of energy materials and devices for visible light harvesting
Creators: name: Zhakeyev, Adilet
Publisher: name: Loughborough University
Year: 2020
Subjects: Chemical engineering not elsewhere classified

description: In recent years, additive manufacturing has become an emerging technology that offers near-complete freedom of design, allowing for complex 3D parts to be readily fabricated. In principle, this enables the implementation of additive manufacturing in a wide-range of applications. However, its application in photochemistry and solar energy harvesting remains, thus far, an uncharted territory. In this work, the versatility in the design and function of 3D printed fluidic devices specifically tailored towards photochemical processes is explored. These reactors have proven to be successful in their implementation in both heterogeneous and homogeneous photosensitisation reactions. The incorporation of a photoactive benzothiadiazole-based photosensitiser into a commercially available 3D printing resin was investigated, and the resulting bespoke resin was successfully used to fabricate photoactive reactionware. The resulting reactionware can act as photosensitisers for the generation of singlet oxygen upon visible light irradiation (420 nm). These 3D printed photosensitising structure were also demonstrated to be highly effective in the degradation of a well-known wastewater contaminant, bisphenol A, under the same visible light irradiation. Due to a great degree of freedom associated with the design of the 3D printed flow devices, it was used for fabrication of monoliths with complex geometries, which showed activity in singlet oxygen generation. Finally, a resin formulation was developed to 3D print photosensitizing structures which are resistant to harsh organic solvents.
title: MRI of sacroiliac joints in patients affected by Seronegative Spondyloarthritis: experimental project with ASAS evaluation guidelines.
Creators: name: Santucci, Gioele
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Oedema
subject: Diagnostic procedure
subject: Technical aspects
subject: MR
subject: Musculoskeletal joint

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The study moves from the recent progresses that modern rheumatology has made in the treatment of patients affected by Seronegative Spondyloarthritis. Sacroiliac joints are involved in the early steps of the pathological process, and sacroiliitis is...
title: Access to a Specialist Endocrine Radiology service reduces the rate of bilateral neck exploration in primary hyperparathyroidism.
Creators: name: Lambon, Ronan
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Ultrasound
subject: Nuclear medicine conventional
subject: Thyroid / Parathyroids
subject: Ear / Nose / Throat
subject: Surgery
subject: Endocrine disorders

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Literature suggests sensitivity of 88% for ultrasonography (USS) and sestimibi scintigraphy for detecting solitary parathyroid adenomas but when combined can be increased up to 95%. 1,2 When these scans are concordant, evidence shows that a...
Crossover between different universality classes: Scaling for thermal transport in one dimension
Creators: name: Xiong, Daxing
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: For thermal transport in one-dimensional (1D) systems, recent studies have suggested that employing different theoretical models and different numerical simulations under different system's parameter regimes might lead to different universality classes of the scaling exponents. In order to well understand the universality class(es), here we perform a direct dynamics simulation for two archetype 1D oscillator systems with quite different phonon dispersions under various system's parameters and find that there is a crossover between the different universality classes. We show that by varying anharmonicity and temperatures, the space-time scaling exponents for the systems with different dispersions can be feasibly tuned in different ways. The underlying picture is suggested to be understood by phonons performing various kinds of continuous-time random walks (in most cases, be the Lévy walks but not always), probably induced by the peculiar phonon dispersions along with nonlinearity. The results and suggested mechanisms may provide insights into controlling the transport of heat in some 1D materials.
description: 6 pages, 6 figures
FE-Simulation Based Design of Wear-Optimized Cutting Edge Roundings
Creators: name: Bergmann, Benjamin
name: Denkena, Berend
name: Beblein, Sascha
name: Picker, Tobias
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: Cutting edge roundings
subject: FE simulation
subject: Wear simulation
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: The performance of cutting tools can be significantly enhanced by matching the cutting edge rounding to the process and material properties. However, the conventional cutting edge rounding design is characterized by a significant number of experimental machining studies, which involve considerable cost, time, and resources. In this study, a novel approach to cutting edge rounding design using FEM-based chip formation simulations is presented. Based on a parameterized simulation model, tool temperatures, stresses and relative velocities can be calculated as a function of tool microgeometry. It can be shown that the external tool loads can be simulated with high agreement. With the help of these loads and the use of wear models, the resulting tool wear and the optimum cutting edge rounding can be determined. The final experimental investigations show a qualitatively high agreement to the simulation, which will enable a reduced effort design of the cutting edge in the future.
Hot Water Treatment for Post-Harvest Disinfestation of Bactrocera dorsalis (Diptera: Tephritidae) and Its Effect on cv. Tommy Atkins Mango
Creators: name: Mwando, Nelson L.
name: Ndlela, Shepard
name: Meyhöfer, Rainer
name: Subramanian, Sevgan
name: Mohamed, Samira A.
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: Mangifera indica
subject: Nonchemical
subject: Oriental fruit fly
subject: Physicochemical parameters
subject: Phytosanitary
subject: Quarantine treatment
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: Mango production and trade in sub-Saharan Africa is hampered by direct damage and the high quarantine status of B. dorsalis and the paucity of effective post-harvest phytosanitary treatments. The current study reports the development of a quarantine treatment protocol using hot water to disinfest B. dorsalis and assess its effect on cv. Tommy Atkins mango quality. We first determined the development of the eggs and all larval stages of B. dorsalis in cv. Tommy Atkins mango and used the information to establish a time–mortality relationship of the immature stages after subjecting infested fruits to a regimen of eight, time instances of hot water at 46.1◦ C. Using probit analysis, we estimated the minimum time required to achieve 99.9968% mortality of each stage. Our results indicate that the egg was the least heat tolerant, followed by the first, second, and third instar. The time required to achieve 99.9968% control of the third instar in cv. Tommy Atkins mango (400–600 g) was determined to be 72.63 min (95% Cl: 70.32–74.95). In the confirmatory trials, the hot water treatment schedule of 46.1◦ C/72.63 min was validated, and none of the 59,120 most heat-tolerant individuals treated survived. Further, there were no significant differences between hot water-treated and untreated mangoes recorded in weight loss, fruit firmness, pH, total soluble solids, moisture content, and titratable acidity eleven days post-treatment. These findings demonstrate an effectively optimum post-harvest disinfestation treatment against B. dorsalis in cv. Tommy Atkins mango that should be adopted commercially to facilitate access to profitable but strict export markets globally.
title: Preoperative embolization of Juvenile angiofibroma with intracranial extension
Creators: name: Amer, Talal
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Ear / Nose / Throat
subject: Interventional vascular
subject: Head and neck
subject: Catheter arteriography
subject: Embolisation
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Juvenile angiofibroma (JAF) is a highly vascular benign tumor of head and neck, found mainly in adolescent males originated from the superior margin of the sphenopalatine foramen, usually spread to the pterygopalatine and infratemporal fossae (1)...
Scaling factors for the in vitro-in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance.
Creators: name: Fallon, John K.
name: Knights, Kathleen M.
name: Smith, Philip C.
name: Spencer, Shane M.
name: Chau, Nuy
name: Miners, John O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: AIM: To determine the scaling factors required for inclusion of renal drug glucuronidation clearance in the prediction of total clearance via glucuronidation (CLUGT ).

METHODS: Microsomal protein per gram of kidney (MPPGK) was determined for human 'mixed' kidney (n = 5) microsomes (MKM). The glucuronidation activities of deferiprone (DEF), propofol (PRO) and zidovudine (AZT) by MKM and paired cortical (KCM) and medullary (KMM) microsomes were measured, along with the UGT 1A6, 1A9 and 2B7 protein contents of each enzyme source. Unbound intrinsic clearances (CLint,u,UGT ) for PRO and morphine (MOR; 3- and 6-) glucuronidation by MKM, human liver microsomes (HLM) and recombinant UGT1A9 and 2B7 were additionally determined. Data were scaled using in vitro-in vivo extrapolation (IV-IVE) approaches to assess the influence of renal CLint,u,UGT on the prediction accuracy of the calculated CLUGT values of PRO and MOR.

RESULTS: MPPGK was 9.3 ± 2.0 mg g(-1) (mean ± SD). The respective rates of DEF (UGT1A6), PRO (UGT1A9) and AZT (UGT2B7) glucuronidation by KCM were 1.4-, 5.2- and 10.5-fold higher than those for KMM. UGT 1A6, 1A9 and 2B7 were the only enzymes expressed in kidney. Consistent with the activity data, the abundance of each of these enzymes was greater in KCM than in KMM. The abundance of UGT1A9 in MKM (61.3 pmol mg(-1) ) was 2.7 fold higher than that reported for HLM.

CONCLUSIONS: Scaled renal PRO glucuronidation CLint,u,UGT was double that of liver. Renal CLint,u,UGT should be accounted for in the IV-IVE of UGT1A9 and considered for UGT1A6 and 2B7 substrates.
Talent development environments within talent pathways in sports: A scoping review examining functional and dysfunctional environmental factors
Creators: name: Hauser, Luca-Lars
name: Wachsmuth, Svenja
name: Höner, Oliver
name: O'Connor, Donna
name: Harwood, Chris
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Sports Studies
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: holistic ecological approach
subject: psychosocial factors
subject: talent development
subject: TDEQ

description: The aim of the forthcoming review is two-folded. First, it aims to provide an up-to-date and critical review of studies investigating TDEs from a holistic ecological perspective that places athletes and their development (incl. personal and sport development as well as wellbeing) centre stage. Second, it aims to analyze this literature with regards to identifying facilitative and destructive factors of talent development settings. More detailed information is available in the pre-registered review protocol.
Experimentally Validated Extension of the Operating Range of an Electrically Driven Turbocharger for Fuel Cell Applications
Creators: name: Schoedel, Markus
name: Menze, Marco
name: Seume, Joerg R.
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: Electrical turbocharger
subject: Fuel cell air supply
subject: Operating range extension
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: From an aerodynamic point of view, the electric turbocharger for the air supply of an automotive fuel cell faces difficult requirements: it must not only control the pressure level of the fuel cell, but it also has to operate with very high efficiency over a wide range. This paper explores features for the compressor and the turbine of an existing electric turbocharger, which are intended to meet the specific requirements of a fuel cell in an experimentally validated numerical study. Adjustable diffuser or nozzle vanes in the compressor and turbine achieve wider operating ranges but compromise efficiency, especially because of the necessary gaps between vanes and end walls. For the turbine, there are additional efficiency losses since the pivoting of the nozzle vanes leads to incidence and thus to flow separation at the leading edge of the nozzle vanes and the rotor blades. An increase in the mass flow and a slight efficiency improvement of the turbine with the low solidity nozzle vanes counteracts these losses. For the compressor, a reduction in the diffuser height and its influence over the operating range and power consumption yields an increase in surge margin as well as in maximum efficiency.
Polarized window for left-right symmetry and a right-handed neutrino at the Large Hadron-Electron Collider
Creators: name: Mondal, Subhadeep
name: Rai, Santosh Kumar
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The breaking of parity, a fundamental symmetry between left and right is best understood in the framework of left-right symmetric extension of the standard model. We show that the production of a heavy right-handed neutrino at the proposed Large Hadron-Electron Collider (LHeC) could give us the most simple and direct hint of the scale of this breaking in left-right symmetric theories. This production mode gives a lepton number violating signal with $ΔL=2$ which is very clean and has practically no standard model background. We highlight that the right-handed nature of $W_R$ exchange which defines the left-right symmetric theories can be confirmed by using a polarized electron beam and also enhance the production rates with relatively lower beam energy.
description: Title changed, published in PRD Rapid Communications
title: Possibilities of X-ray densitometry in young children
Creators: name: ARSENIDZE, Tetiana
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Bones
subject: Absorptiometry / Bone densitometry
subject: Diagnostic procedure
subject: Osteoporosis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Osteoporosis can cause by various bones and joints diseases, including hip dysplasia - one of the most common musculoskeletal disease in infants and young children. Bone mineral density is one of the most important factors that determine its...
title: CT Peritoneography: Findings in complications of peritoneal dialysis.
Creators: name: Calvo Blanco, Juan
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: CT
subject: Technical aspects
subject: Hernia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - To know CT Peritoneography indications and technique - To describe the findings in complications of peritoneal...
title: Peritoneal cavity anatomy in CT Peritoneography: a comprehensive description.
Creators: name: Calvo Blanco, Juan
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Anatomy
subject: CT
subject: Education
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To know CT Peritoneography indications and technique. To review the normal peritoneal cavity anatomy by CT...
The mass action equation in pharmacology: Mass action applied to pharmacology
Creators: name: Kenakin, Terry
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The mass action equation is the building block from which all models of drug–receptor interaction are built. In the simplest case, the equation predicts a sigmoidal relationship between the amount of drug–receptor complex and the logarithm of the concentration of drug. The form of this function is also the same as most dose–response relationships in pharmacology (such as enzyme inhibition and the protein binding of drugs) but the potency term in dose–response relationships very often differs in meaning from the similar term in the simple mass action relationship. This is because (i) most pharmacological systems are collections of mass action reactions in series and/or in parallel and (ii) the important assumptions in the mass action reaction are violated in complex pharmacological systems. In some systems, the affinity of the receptor R for some ligand A is modified by interaction of the receptor with the allosteric ligand B and concomitantly the affinity of the receptor for ligand B is modified to the same degree. When this occurs, the observed affinity of the ligand A for the receptor will depend on both the concentration of the co‐binding allosteric ligand and its nature. The relationships between drug potency in pharmacological models and the equilibrium dissociation constants defined in single mass action reactions are discussed. More detailed knowledge of efficacy has led to new models of drug action that depend on the relative probabilities of different states, and these have taken knowledge of drug–receptor interactions beyond Guldberg and Waage.
Oberst Alphons Pfyffer von Altishofen (1834-1890)
Creators: name: (:Unkn) Unknown
Publisher: name: Zentralbibliothek Zürich
Year: 1890
Subjects: subject: 355 Militärwissenschaft
subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Pfyffer von Altishofen, Max
subject: Luzern
subject: Altishofen

description: verschiedene Nekrologe aus Zeitungen und Zeitschriften
How do children feel about hierarchical groups?
Creators: name: Thomas, Ashley
name: Mitchell, VIvian
name: Terrizzi, Brandon
name: Piff, Paul
name: Sumner, Emily
name: Sarnecka, Barbara
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: In the current study we ask whether children spontaneously pick up on the structure of groups based on who makes decisions, whether recognizing differences in structures influences decision preference for groups, and whether children infer that groups that are hierarchical in decision making distribute physical resources less as well.
Reservoir interactions during Bose-Einstein condensation: modified critical scaling in the Kibble-Zurek mechanism of defect formation
Creators: name: McDonald, R. G.
name: Bradley, A. S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: As a test of the Kibble-Zurek mechanism (KZM) of defect formation, we simulate the Bose-Einstein condensation transition in a toroidally confined Bose gas using the stochastic projected Gross-Pitaevskii equation (SPGPE), with and without the energy-damping reservoir interaction. Energy-damping alters the scaling of the winding number distribution with the quench time - a departure from the universal KZM theory that relies on equilibrium critical exponents. Numerical values are obtained for the correlation-length critical exponent $ν$ and the dynamical critical exponent $z$ for each variant of reservoir interaction theory. The energy-damping reservoir interactions cause significant modification of the dynamical critical exponent of the phase transition, whilst preserving the essential KZM critical scaling behavior. Comparison of numerical and analytical two-point correlation functions further illustrates the effect of energy damping on the correlation length during freeze out.
description: 10 pages, 7 figures
title: The top 30 mnemonics for radiology residents, a useful revision tool
Creators: name: Gupta, Amit
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Anatomy
subject: RIS
subject: Diagnostic procedure
subject: Acute

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The aim of this resource is to provide a simple yet effective way of remembering key radiological differential diagnoses. Residents may use this resource to prepare for exam boards. Attendings may use this resource to refresh their memory. Everyone...
title: Final year radiography degree students' coping mechanisms for perceived stressors in the clinical environment.
Creators: name: O'Leary, Desiree
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Education and training
subject: Socio-economic issues
subject: Digital radiography
subject: Professional issues

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Stress and the individual Stress is considered to arise from an interaction between an individual and the environment, where the individual interprets the situation as threatening, challenging and damaging (Spiers, 2007). In the working environment...
Quantum Cosmological Perturbations of Multiple Fluids
Creators: name: Peter, Patrick
name: Pinto-Neto, Nelson
name: Vitenti, Sandro Dias Pinto
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The formalism to treat quantization and evolution of cosmological perturbations of multiple fluids is described. We first construct the Lagrangian for both the gravitational and matter parts, providing the necessary relevant variables and momenta leading to the quadratic Hamiltonian describing linear perturbations. The final Hamiltonian is obtained without assuming any equations of motions for the background variables. This general formalism is applied to the special case of two fluids, having in mind the usual radiation and matter mix which made most of our current Universe history. Quantization is achieved using an adiabatic expansion of the basis functions. This allows for an unambiguous definition of a vacuum state up to the given adiabatic order. Using this basis, we show that particle creation is well defined for a suitable choice of vacuum and canonical variables, so that the time evolution of the corresponding quantum fields is unitary. This provides constraints for setting initial conditions for an arbitrary number of fluids and background time evolution. We also show that the common choice of variables for quantization can lead to an ill-defined vacuum definition. Our formalism is not restricted to the case where the coupling between fields is small, but is only required to vary adiabatically with respect to the ultraviolet modes, thus paving the way to consistent descriptions of general models not restricted to single-field (or fluid).
description: 20 pages, matches PRD published version
A phase II trial of bendamustine in combination with rituximab in older patients with previously untreated diffuse large B-cell lymphoma
Creators: name: Ivanova, Anastasia
name: Park, Steven I.
name: Shea, Thomas C.
name: Wall, James G.
name: Richards, Kristy L.
name: Foster, Matthew C.
name: Sobol, Anna L.
name: Asch, Adam S.
name: Deal, Allison M.
name: Olajide, Oludamilola
name: Grover, Natalie S.
name: Muss, Hyman B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Bendamustine in combination with rituximab (BR) has been associated with high response rates and acceptable toxicity in older patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL). Evaluation of BR is warranted in the front-line setting for DLBCL patients not eligible for anthracyclines or for the elderly. In this phase II study, we enrolled DLBCL patients aged ≥65 years who were poor candidates for R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) to determine the efficacy and safety of BR in previously untreated stage II–IV DLBCL. Twenty-three patients were enrolled with a median age of 80 years. 52% of patients presented with poor functional status (Eastern Cooperative Oncology Group performance score of ≥2). The overall response rate was 78% with 12 complete responses (52%). At a median follow up of 29 months, the median overall survival was 10.2 months and the median progression-free survival was 5.4 months. The most common grade 3/4 adverse events were haematological. Combination therapy with BR demonstrates high response rates as front-line therapy in frail older patients with DLBCL, but survival rates were low. BR should be used with caution in future clinical trials involving older DLBCL patients with poor functional status.
title: Audit of waiting time for imaging investigations ordered from a rheumatology outpatient department
Creators: name: Clifford, Simon
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal joint
subject: Musculoskeletal soft tissue
subject: CT
subject: MR
subject: Absorptiometry / Bone densitometry
subject: Efficacy studies
subject: Cost-effectiveness
subject: Education
subject: Economics
subject: Workforce

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Timely access to a wide variety of imaging modalities is essential for diagnosis and management. It is useful to be able to predict the length of time a patient will be awaiting a particular scan, as some treatments may be delayed until after a...
Spin fluctuations and superconductivity in layered $f$-electron superlattices
Creators: name: Tada, Yasuhiro
name: Peters, Robert
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate magnetic and superconducting properties of layered $f$-electron superlattices within the fluctuation exchange approximation (FLEX). We show that spin fluctuations, which are characterized by the maximum value of the spin susceptibility in the 3-dimensional (3D) Brillouin zone, are strongly suppressed in $f$-electron superlattices. However, effective 2D spin fluctuations can be increased due to the spatial confinement of the $f$-electrons. Therefore, the tendency towards $d_{x^2-y^2}$-wave superconductivity, mediated by these spin fluctuations, can be strongly increased in $f$-electron-superlattices. This is in sharp contrast to superlattices composed of conventional $s$-wave superconductors, where superconductivity is generally suppressed.
description: 8 pages
بررسی میزان تمایل به حفاظت از جنگل های دست کاشت استان تهران در سطوح مختلف معیشتی و عوامل موثر بر آن
Publisher: name: دانشگاه کردستان
Year: 2022

description: افزایش جمعیت، رشد شهرنشینی و تبدیل شهرها به کانون فعالیت های اقتصادی و اجتماعی و همچنین استقرار بنگاه های صنعتی تولیدی و به دنبال آن کاهش زمین های کشاورزی و فضاهای سبز طبیعی، توسعه فضاهای سبز شهری و جنگل های دست کاشت را در استان تهران اجتناب ناپذیر کرده است. داده های مورد نیاز این پژوهش از طریق تکمیل پرسشنامه آنلاین دوگانه دو بعدی با نمونه 404 پاسخگو که با روش کوکران اورکات استخراج و برای بررسی عوامل مؤثر بر میزان تمایل به پرداخت افراد، از الگوی لاجیت و روش حداکثر راستنمایی استفاده شد. نتایج حاصل از این پژوهش با استفاده از نرم ­افزارهای اس.پی.اس.اس (جهت بررسی ویژگی های اقتصادی - اجتماعی)، شزم10 (جهت برآورد تابع لاجیت)،ولفرام آلفا (جهت برآورد انتگرال عددی)، استخراج  گردید. متوسط تمایل به پرداخت سالیانه هر نفر ۱۱۵.۷۴۴ ریال به دست آمد و متغیرهای اخلاق گرایی در پرداخت ها، تحصیلات، سن و جمعیت خانوار از مهم ترین عوامل تاثیر گذار مثبت و معنی دار بر تمایل به پرداخت افراد برای حفاظت از جنگل های دست کاشت هستند. با توجه به نتایج حاصله که میزان تاثیر عوامل پیامدگرایانه را منفی و متقابلا تاثیر عوامل وظیفه گرایانه را مثبت شناسایی می کند، پیشنهاد می شود با سرمایه گذاری در این بخش فرهنگ سازی، آموزش و تبلیغات و شناساندن ارزش های این مناطق را به سمت وظیفه گرایانه مبتنی بر مولفه های اخلاقی سوق داد
title: Contrast-enhanced MDCT in clear cell renal adenocarcinoma: correlation with Fuhrman grade
Creators: name: Gal'china, Julia
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Kidney
subject: CT
subject: CT-Quantitative
subject: Comparative studies
subject: Diagnostic procedure
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The purpose of this study was to evaluate correlation between clear cell renal carcinoma contrast enhancement patterns and Fuhrman grade. Correlation between largest dimension of the renal mass, its margins, native phase density, renal capsule...
title: Acetabular fractures: CT diagnosis and 3D volume rendering contribution
Creators: name: Zaouali, Skander
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Anatomy
subject: Bones
subject: Trauma
subject: CT
subject: Image manipulation / Reconstruction
subject: Computer Applications-3D
subject: Education
subject: Trauma

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Surgical treatment of acetabular fractures is very dependent of an accurate diagnosis and a precise classification of the lesions. Computed Tomography is the key examination for a full review of all acetabular fractures. Because of the complex...
بررسی تأثیر تروریسم بر شاخص بازده بازار سهام در کشورهای خاورمیانه
Publisher: name: دانشگاه کردستان
Year: 2022

description: افزایش بازار سهام نقش مهم و حیاتی در تشکیل سرمایه و تجمیع سرمایه های کوچک\nسرگردان و هدایت آنها به سوی مسیرهای مطلوب در سیستم های اقتصادی یک کشور دارد\nسرمایه گذاران در دنیای پر تلاطم امروزی، ضمن بررسی و آگاهی نسبت به عوامل اقتصادی\nتاثیرگذار بر بازار سهام، از سایر عوامل سیاسی )ثبات سیاسی، حکمرانی خوب، فساد، فعالیت-\nهای تروریستی و حقوق مالکیت( اثرگذار بر بازده بازار سهام نیز باید آگاهی داشته باشند. عوامل\nسیاسی مخصوصا فعالیتهای تروریستی موجب ایجاد عدم اطمینان، کاهش اعتماد، افزایش\nدرک ریسک، کاهش اعتماد سرمایهگذاری و تجارت خارجی، فرار سرمایه میگردد. لذا،\nحملات تروریستی منجر به کاهش سود شرکت و آشفتگی و ابهام در میان سرمایه گذاران،\nخروج سرمایه گذاران از بازار سهام، و افت بازده بازار سهام میشود. بنابراین بررسی ارتباط بین\n فعالیتهای تروریستی و تاثیر آن بر بازده بازار سهام منطقه پر تنش خاورمیانه از اهمیت بالایی برخوردار است. از این رو، هدف تحقیق حاضر بررسی تاثیر تروریسم بر شاخص بازده بازار سهام\nدر منطقه پر مخاطره خاورمیانه طی بازه زمانی 2008-2019 با رویکرد گشتاورهای تعمیم یافته\nاست. نتایج تحقیق حاکی از این واقعیت میباشد که مطابق با انتظارات تئوریکی تحقیق، فعالیت\nهای تروریستی تاثیر منفی و معنیداری بر بازده بازار سهام در کشورهای مذکور دارد. از سایر\nنتایج تحقیق، متغیرهای نرخ ارز واقعی و قیمت نفت تاثیر منفی و معنیدار بر بازده بازار سهام\nدارند، در حالیکه متغیر نرخ رشد اقتصادی تاثیری مثبت و معنیدار بر بازده بازار سهام دارد
Outcomes for paediatric Burkitt lymphoma treated with anthracycline-based therapy in Malawi
Creators: name: Mtete, Idah
name: Montgomery, Nathan D.
name: Gopal, Satish
name: Chasela, Mary
name: Chimzimu, Fred
name: Heimlich, Brett J.
name: Kaimila, Bongani
name: Stanley, Christopher C.
name: Chikasema, Mary
name: Rosenberg, Nora E.
name: Makwakwa, Victor
name: Kasonkanji, Edwards
name: Kampani, Coxcilly
name: Krysiak, Robert
name: Wasswa, Peter
name: Butia, Mercy
name: Itimu, Salama
name: Dhungel, Bal M.
name: Liomba, N. George
name: El-Mallawany, Nader K.
name: Westmoreland, Kate D.
name: Mtunda, Mary
name: Fedoriw, Yuri
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Burkitt lymphoma (BL) is the most common paediatric cancer in sub-Saharan Africa (SSA). Anthracyline-based treatment is standard in resource-rich settings, but has not been described in SSA. Children ≤ 18 years of age with newly diagnosed BL were prospectively enrolled from June 2013 to May 2015 in Malawi. Staging and supportive care were standardized, as was treatment with CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) for six cycles. Among 73 children with BL, median age was 9.2 years (interquartile range 7.7–11.8), 48 (66%) were male and two were positive for human immunodeficiency virus. Twelve (16%) had stage I/II disease, 36 (49%) stage III and 25 (34%) stage IV. Grade 3/4 neutropenia occurred in 17 (25%), and grade 3/4 anaemia in 29 (42%) of 69 evaluable children. Eighteen-month overall survival was 29% (95% confidence interval [CI] 18–41%) overall. Mortality was associated with age >9 years [hazard ratio [HR] 2.13, 95% CI 1.15–3.94], female gender (HR 2.12, 95% CI 1.12–4.03), stage (HR 1.52 per unit, 95% CI 1.07–2.17), lactate dehydrogenase (HR 1.03 per 100 iu/l, 95% CI 1.01–1.05), albumin (HR 0. 96 per g/l, 95% CI 0.93–0.99) and performance status (HR 0.78 per 10-point increase, 95% CI 0.69–0.89). CHOP did not improve outcomes in paediatric BL compared to less intensive regimens in Malawi.
title: Role Of Cyberknife Robotic Radiosurgery in Surgically Unresectable Paediatric Intracranial Mass Lesions causing Epilepsy--- A Cyberknife JPMC Experience
Creators: name: Arooj, Shumaila
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: MR
subject: Radiation therapy / Oncology
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Cyberknife Robotic Radiosurgery System is a non invasive alternative to surgery for the treatment of cancerous or non cancerous tumors anywhere in body.It is a method of delivering radiotherapy, with the intention of targeting treatment more...
Does being feminine give an advantage to female politicians in system-threat situations?
Creators: name: Nakagoshi, Mizuki
name: Inamasu, Kazunori
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Physical Sciences and Mathematics
subject: Social and Behavioral Sciences

description: Pre-analysis plan for the project: Does being “feminine” give an advantage to female politicians in system-threat situations?
title: MRI in the study of the fetal gastrointestinal system.
Creators: name: Gómez Huertas, María
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: MR
subject: Paediatric
subject: Gastrointestinal tract
subject: Education
subject: Technical aspects
subject: Congenital

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe the technique. To assess MR indications and utility. To describe fetal MR features related to embryological development and to the most frequent congenital anomalies of the gastrointestinal tract. To describe our...
title: Dual-energy X-ray absorptiometry, bioimpedance analysis, and anthropometry: Body composition assessment in young congenital lipodistrophic individuals
Creators: name: Velloso, Renata
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Absorptiometry / Bone densitometry
subject: Soft tissues / Skin
subject: Comparative studies
subject: Endocrine disorders

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: A significant amount of body composition research has focused on methodologies like bioimpedance analysis (BIA) and dual energy X-Ray absorptiometry (DXA) for the assessment of per cent body fat and fat-free mass. Here we have conducted a analysis...
بررسی و تحلیل اثرات نامتقارن تکانه های قیمت نفت بر بیکاری بخشی در ایران
Publisher: name: دانشگاه کردستان
Year: 2022

description: باتوجه به اهمیت نفت در کشورهای صادرکننده، نوسانات قیمت نفت علاوه بر تاثیرگذاری\nبر اقتصاد کشورهای واردکننده، بزرگترین منبع اختلال در اقتصاد و به خصوص در\nبیکاری کشورهای وابسته به نفت محسوب میشود. از این رو در مطالعه حاضر به بررسی\nاثرات تکانه های قیمت نفت بر بیکاری بخشی در ایران در بازه زمانی 1998 تا 2019 با\nاستفاده از الگوی تصحیح خطای برداری پرداخت ها است. یافته های تحقیق نشان میدهد\nکه نمودار واکنش توابع بیکاری بخش کشاورزی، صنعت و خدمات نسبت به شوک\nقیمت نفت طی دورههای مختلف متفاوت بوده و در بعضی دورهها بهبود و در بعضی\n دوره ها کاهش یافته است.همچنین با استناد به جدول های تجزیه واریانس میتوان اذعان نمود که تغییرات عمده توابع بیکاری بخش های کشاورزی و صنعت مربوط به تغییرات\nقیمت نفت بوده و تغییرات بیکاری بخش خدمات نیز ناشی از تغییرات نرخ بهره بوده است