cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Groin Complications Following Therapeutic Interventional Neuroradiology Procedures: A Single Center Experience
Creators: name: Gajera, Jay
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Haemorrhage
subject: Outcomes
subject: Haemodynamics / Flow dynamics
subject: Puncture
subject: Arterial access
subject: Catheter arteriography
subject: Interventional vascular
subject: Neuroradiology brain

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The role of interventional neuroradiology (INR) in the treatment of cranial vessel disorders is expanding. The common femoral artery (CFA) is the most common access site for endovascular procedures and groin complications such as localised...
Sonnenfleckenzeichnung Nr. 184.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.08.2008, 06:45, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Aspilia leucanthema Chodat, Bull. Herb. Boissier
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Aspilia
Aspilia leucanthema

description: Aspilia leucanthema Chodat, Bull. Herb. Boissier, sér. 2(2): 391. 1902.
Subshrub.
 Vouchers: Amambay: Basualdo 4875 (FCQ); Brunner et al. 968 (MO, PY); Hassler 9740 (K); Krapovickas et al. 45928 (CTES, K); Krapovickas et al. 46013 (CTES, K); Schinini & Dematteis 33438 (CTES, FCQ, K, MO, SI); Solomon et al. 7064 (MO, PY); Soria 5659 (MO); Soria 5772 (FCQ, K, MO); Soria 6072 (MO); Soria 6295 (FCQ); Soria 7238 (FCQ); Soria 7385 (FCQ, MO); Stevens et al. 26042 (FCQ, K, MO); Zardini & Báez 52220 (AS, MO); Zardini et al. 4163 (FCQ, K, MO). Canindeyú: Hassler 4988, type (K). San Pedro: Zardini & Guerrero 45538 (AS, MO); Zardini & Guerrero 46668 (AS, K, MO); Zardini & Guerrero 46941 (AS, K, MO); Zardini & Guerrero 48169 (AS, MO); Zardini & Guerrero 48369 (AS, MO); Zardini & Vargas 43625 (MO, PY); Zardini & Vargas 43631 (MO, PY); Zardini & Zavala 44195 (AS, MO); Zardini & Zavala 46871 (AS, K, MO).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Sonnenfleckenzeichnung Nr. 240.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.10.2008, 07:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: The Utility of 18-FDG PET to Streamline Dental Extractions Prior to Radiation Therapy Using Volumetric Modulated Arc Therapy (VMAT)
Creators: name: Rai, Divyajeet
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Oncology
subject: PET-CT
subject: Computer Applications-3D
subject: Biological effects

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Introduction: Osteoradionecrosis (ORN) of the mandible is a well-recognised late complication of high dose radiotherapy (RT) for head and neck cancer. The incidence of mandibular ORN following RT varies between 2% and 22% [1] and is often...
$Z_2$-gauge theory description of the Mott transition in infinite dimensions
Creators: name: Zitko, Rok
name: Fabrizio, Michele
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The infinite dimensional half-filled Hubbard model can be mapped exactly with no additional constraint onto a model of free fermions coupled in a $Z_2$ gauge-invariant manner to auxiliary Ising spins in a transverse field. In this slave-spin representation, the zero-temperature insulator-to-metal transition translates into spontaneous breaking of the local $Z_2$ gauge symmetry, which is not forbidden in infinite dimensions, thus endowing the Mott transition of an order parameter that is otherwise elusive in the original fermion representation. We demonstrate this interesting scenario by exactly solving the effective spin-fermion model by dynamical mean-field theory both at zero and at finite temperature.
description: 10 pages, 8 figures
Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca 2+ Signaling
Creators: name: El Bakkouri, Majida
name: Triana, Miryam A. Hortua
name: Moreno, Silvia N. J.
name: Duraisingh, Manoj T.
name: Westwood, Nicholas J.
name: Paul, Aditya S.
name: Sidik, Saima M.
name: Tran, Fanny
name: Hui, Raymond
name: Lourido, Sebastian
name: Hackett, Caroline G.
name: Zuercher, William J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The life cycles of apicomplexan parasites progress in accordance with fluxes in cytosolic Ca2+. Such fluxes are necessary for events like motility and egress from host cells. We used genetically encoded Ca2+ indicators (GCaMPs) to develop a cell-based phenotypic screen for compounds that modulate Ca2+ signaling in the model apicomplexan Toxoplasma gondii. In doing so, we took advantage of the phosphodiesterase inhibitor zaprinast, which we show acts in part through cGMP-dependent protein kinase (protein kinase G; PKG) to raise levels of cytosolic Ca2+. We define the pool of Ca2+ regulated by PKG to be a neutral store distinct from the endoplasmic reticulum. Screening a library of 823 ATP mimetics, we identify both inhibitors and enhancers of Ca2+ signaling. Two such compounds constitute novel PKG inhibitors and prevent zaprinast from increasing cytosolic Ca2+. The enhancers identified are capable of releasing intracellular Ca2+ stores independently of zaprinast or PKG. One of these enhancers blocks parasite egress and invasion and shows strong antiparasitic activity against T. gondii. The same compound inhibits invasion of the most lethal malaria parasite, Plasmodium falciparum. Inhibition of Ca2+-related phenotypes in these two apicomplexan parasites suggests that depletion of intracellular Ca2+ stores by the enhancer may be an effective antiparasitic strategy. These results establish a powerful new strategy for identifying compounds that modulate the essential parasite signaling pathways regulated by Ca2+, underscoring the importance of these pathways and the therapeutic potential of their inhibition.
title: Culture Hacks für eine bessere UX-Kultur
Creators: name: Winter, Dominique
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2022
Subjects: subject: UX-Kompetenzen
subject: Change Management
subject: UX-Reife
subject: Unternehmenskultur

description: Ein wichtiger Baustein für Unternehmen, die mit ihren Produkten eine gute User Experience (UX) erzeugen wollen, ist die Unternehmenskultur. Die Kultur greift überall dort, wo Prozesse, Werkzeuge und andere Formalismen nicht mehr wirken. Eine Kultur aber gezielt in eine für die UX relevante Richtung zu verändern ist schwer bis kaum möglich. Große Change-Projekte rund um die Unternehmenskultur erzielen oft nicht die gewünschte Wirkung; die Veränderungen waren zu groß und die Beharrungskräfte der Organisationen waren stärker. Genau hier greift das Konzept des Culture Hackings an, denn dieser Ansatz umfasst die Umsetzung zahlreicher kleiner, positiver Veränderungen in einer Organisation. Diese Veränderungen werden meist aus der Motivation der Mitarbeitenden selbst herausgetrieben und stehen nicht in Konflikt zu den bisherigen Formalismen. In diesem Beitrag werden Erfahrungen aufgezeigt, wie man in einer Organisation Culture Hacks zur Steigerung der organisationalen UX-Kompetenz entwickeln und einführen kann aber auch welche Fallstricke es zu vermeiden gilt.
Sonnenfleckenzeichnung Nr. 87.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.04.2008, 08:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Solid Pulmonary Nodules (SPNs): An Update on the Approach to Investigation
Creators: name: Dissanayake, Shashini
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Lung
subject: Oncology
subject: CT
subject: PET-CT
subject: Biopsy
subject: Cancer

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: Investigation of SPNs should be guided by risk of...
Metamaterials: $\textit{supra}$-classical dynamic homogenization
Creators: name: Caleap, Mihai
name: Drinkwater, Bruce W
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 78A40, 78A45, 78A48, 78M16, 78M40, 74Q15, 74Jxx, 74H05, 74H10

description: Metamaterials are artificial composite structures designed for controlling waves or fields, and exhibit interaction phenomena that are unexpected on the basis of their chemical constituents. These phenomena are encoded in effective material parameters that can be electronic, magnetic, acoustic, or elastic, and must adequately represent the wave interaction behaviour in the composite within desired frequency ranges. In some cases -- for example, the low frequency regime -- there exist various efficient ways by which effective material parameters for wave propagation in metamaterials may be found. However, the general problem of predicting frequency-dependent dynamic effective constants has remained unsolved. Here, we obtain novel mathematical expressions for the effective parameters of two-dimensional metamaterial systems valid at higher frequencies and wavelengths than previously possible. By way of an example, random configurations of cylindrical scatterers are considered, in various physical contexts: sound waves in a compressible fluid, anti-plane elastic waves, and electromagnetic waves. Our results point towards a paradigm shift in our understanding of these effective properties, and metamaterial designs with functionalities beyond the low-frequency regime are now open for innovation.
description: 14 pages (including 4 figures and 1 table) in New Journal of Physics, 2015
title: Assessment of Skeletal Metastases in Prostate Cancer: 68Ga-PSMA PET vs 99mTc-MDP WBBS - A Case Series
Creators: name: Bennett, Olivia
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Genital / Reproductive system male
subject: Oncology
subject: Nuclear medicine
subject: PET-CT
subject: Nuclear medicine conventional
subject: SPECT-CT
subject: Diagnostic procedure
subject: Staging
subject: Cancer
subject: Neoplasia

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To compare 99m Technetium-hydroxymethylenediphosphonate ( 99m Tc-HDP) whole body bone scan (WBBS) and 68 Gallium ( 68 Ga)-prostate-specific membrane antigen ligand positron emission tomography/computed tomography (PSMA-PET/CT) for the assessment of...
Sonnenfleckenzeichnung Nr. 173.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.07.2008, 07:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Baccharis amambayensis Zardini & Soria, Candollea
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Baccharis
Baccharis amambayensis

description: Baccharis amambayensis Zardini & Soria, Candollea 46: 535. 1991.
Shrub.
 Vouchers: Amambay: Hassler 10285 (G); Hassler 10285a, type (A, BM, F, G, GH, NY, P); Schinini & Dematteis 33760 (G).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation
Creators: name: Garvey, Leslie
name: Yin, Guowei
name: Bagni, Rachel K.
name: Der, Channing J.
name: Huynh, Minh
name: Kistler, Samantha
name: Campbell, Sharon L.
name: Lammers, Michael
name: Kuhlmann, Nora
name: George, Samuel D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The KRAS GTPase plays a critical role in the control of cellular growth. The activity of KRAS is regulated by guanine nucleotide exchange factors (GEFs), GTPase-activating proteins (GAPs), and also post-translational modification. Lysine 104 in KRAS can be modified by ubiquitylation and acetylation, but the role of this residue in intrinsic KRAS function has not been well characterized. We find that lysine 104 is important for GEF recognition, because mutations at this position impaired GEF-mediated nucleotide exchange. Because the KRAS K104Q mutant has recently been employed as an acetylation mimetic, we conducted a series of studies to evaluate its in vitro and cell-based properties. Herein, we found that KRAS K104Q exhibited defects in both GEF-mediated exchange and GAP-mediated GTP hydrolysis, consistent with NMR-detected structural perturbations in localized regions of KRAS important for recognition of these regulatory proteins. Despite the partial defect in both GEF and GAP regulation, KRAS K104Q did not alter steady-state GTP-bound levels or the ability of the oncogenic KRAS G12V mutant to cause morphologic transformation of NIH 3T3 mouse fibroblasts and of WT KRAS to rescue the growth defect of mouse embryonic fibroblasts deficient in all Ras genes. We conclude that the KRAS K104Q mutant retains both WT and mutant KRAS function, probably due to offsetting defects in recognition of factors that up-regulate (GEF) and down-regulate (GAP) RAS activity.
The rate of convergence of Nesterov's accelerated forward-backward method is actually faster than $1/k^{2}$
Creators: name: Attouch, Hedy
name: Peypouquet, Juan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: The {\it forward-backward algorithm} is a powerful tool for solving optimization problems with a {\it additively separable} and {\it smooth} + {\it nonsmooth} structure. In the convex setting, a simple but ingenious acceleration scheme developed by Nesterov has been proved useful to improve the theoretical rate of convergence for the function values from the standard $\mathcal O(k^{-1})$ down to $\mathcal O(k^{-2})$. In this short paper, we prove that the rate of convergence of a slight variant of Nesterov's accelerated forward-backward method, which produces {\it convergent} sequences, is actually $o(k^{-2})$, rather than $\mathcal O(k^{-2})$. Our arguments rely on the connection between this algorithm and a second-order differential inclusion with vanishing damping.
title: Inter-Observer Variation of Polyp Measurement at CT Colonography (CTC)
Creators: name: Dulku, Gurjeet
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Observer performance
subject: Computer Applications-Detection, diagnosis
subject: Colonography CT
subject: CT
subject: CAD
subject: Colon
subject: Abdomen
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The concept of ‘advanced polyps’ is well accepted - polyps ≥10 mm and/or a villous component and/or areas of dysplasia. CTC can only document size. The management of CTC-discovered ‘advanced polyps’ is to recommend excision, whereas...
Sonnenfleckenzeichnung Nr. 47.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.02.2008, 08:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Imaging Techniques in Improving Image Quality of CT Abdomen: What Are the Latest?
Creators: name: Lau, Kenneth
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Abdomen
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Technical aspects
subject: Artifacts
subject: Kv imaging

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: The aim of this exhibit is to review various latest imaging techniques that can improve the image quality and diagnostic utility of CT of abdomen and...
Baccharis illinitoides Malag., Mem. Soc. Ci. Nat. La Salle
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Baccharis
Baccharis illinitoides

description: Baccharis illinitoides Malag., Mem. Soc. Ci. Nat. La Salle 37: 138. 1977.
Shrub.
 Vouchers: Amambay: Hassler & Rojas 10049 (G); Hassler & Rojas 10049a (BM, G); Hassler & Rojas 10049b (G); Hassler & Rojas 10392 (G); Hassler & Rojas 10392a, type (G); Schinini et al. 29271 (CTES, FCQ, G); Soria 7606 (FCQ); Zardini & Cardozo 45205 (AS, MO). Caaguazú: Hassler 9054 (G); Hassler 9054a (G).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Spinocerebellar ataxia type 14: refining clinicogenetic diagnosis in a rare adult‐onset disorder
Creators: name: Schmitz‐Hübsch, Tanja
name: Lux, Silke
name: Bauer, Peter
name: Brandt, Alexander U.
name: Schlapakow, Elena
name: Greschus, Susanne
name: Scheel, Michael
name: Gärtner, Hanna
name: Kirlangic, Mehmet E.
name: Gras, Vincent
name: Timmann, Dagmar
name: Synofzik, Matthis
name: Giorgetti, Alejandro
name: Carloni, Paolo
name: Shah, Jon N.
name: Schöls, Ludger
name: Kopp, Ute
name: Bußenius, Lisa
name: Oberwahrenbrock, Timm
name: Zimmermann, Hanna
name: Pfueller, Caspar
name: Kadas, Ella‐Maria
name: Rönnefarth, Maria
name: Grosch, Anne‐Sophie
name: Endres, Matthias
name: Amunts, Katrin
name: Paul, Friedemann
name: Doss, Sarah
name: Minnerop, Martina
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: Age of Onset
subject: Cross-Sectional Studies
subject: Disease Progression
subject: Protein Kinase C
subject: Spinocerebellar Ataxias
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objectives: Genetic variant classification is a challenge in rare adult-onset disorders as in SCA-PRKCG (prior spinocerebellar ataxia type 14) with mostly private conventional mutations and nonspecific phenotype. We here propose a refined approach for clinicogenetic diagnosis by including protein modeling and provide for confirmed SCA-PRKCG a comprehensive phenotype description from a German multi-center cohort, including standardized 3D MR imaging. Methods: This cross-sectional study prospectively obtained neurological, neuropsychological, and brain imaging data in 33 PRKCG variant carriers. Protein modeling was added as a classification criterion in variants of uncertain significance (VUS). Results: Our sample included 25 cases confirmed as SCA-PRKCG (14 variants, thereof seven novel variants) and eight carriers of variants assigned as VUS (four variants) or benign/likely benign (two variants). Phenotype in SCA-PRKCG included slowly progressive ataxia (onset at 4-50 years), preceded in some by early-onset nonprogressive symptoms. Ataxia was often combined with action myoclonus, dystonia, or mild cognitive-affective disturbance. Inspection of brain MRI revealed nonprogressive cerebellar atrophy. As a novel finding, a previously not described T2 hyperintense dentate nucleus was seen in all SCA-PRKCG cases but in none of the controls. Interpretation: In this largest cohort to date, SCA-PRKCG was characterized as a slowly progressive cerebellar syndrome with some clinical and imaging features suggestive of a developmental disorder. The observed non-ataxia movement disorders and cognitive-affective disturbance may well be attributed to cerebellar pathology. Protein modeling emerged as a valuable diagnostic tool for variant classification and the newly described T2 hyperintense dentate sign could serve as a supportive diagnostic marker of SCA-PRKCG.
Sonnenfleckenzeichnung Nr. 227.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.09.2008, 09:30, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
A property of a partial theta function
Creators: name: Kostov, Vladimir Petrov
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: The series $θ(q,x):=\sum _{j=0}^{\infty}q^{j(j+1)/2}x^j$ converges for $|q|<1$ and defines a {\em partial theta function}. For any fixed $q\in (0,1)$ it has infinitely many negative zeros. It is known that for $q$ taking one of the {\em spectral} values $\tilde{q}_1$, $\tilde{q}_2$, $\ldots$ (where $0.3092493386\ldots =\tilde{q}_1
Source code for getting short time emission results in EPISODE-CityChem
Creators: name: Pan, Kang
Publisher: name: Zenodo
Year: 2022
Subjects: short time output

description: Here are the source codes that can calculate and get the emission results in specified location with short time (every simulation step, can be in minute) , integrated with EPISODE-CityChem v1.3 (should work with later version as well). The code works together with the moving point source model (MPS) developed by the Kang Pan (https://doi.org/10.5281/zenodo.4650482).
The GAMIFICATION TO IMPROVE LEARNERS’ HANDWRITING IN PRIMARY AND MIDDLE SCHOOL STUDENTS OF HYDERABAD INSTITUTE OF EXCELLENCE
Creators: name: Lawrance, Paul Joseph
name: Begum, Naziya
name: MOREIRA, ANTÓNIO
Publisher: name: Internet Latent Corpus Journal
Year: 2023

description: Good handwriting is essential for a student to develop during school days. Writing by hand involves intricate movements which activate more areas of the brain, and strengthen memory power, muscle power, and concentration span. The gamification concept was applied to improve students' handwriting in primary and middle school students. Game elements like points, badges, and prizes were used to motivate students. The research was carried out at Hyderabad Institute of Excellence, Mudgula Chitampally, Vikarabad District, Telangana State, India. A case study was used as a method in this research. Two rounds of handwriting competitions were conducted for both primary and middle school students, and qualitative and quantitative methods were used to collect data. Instant effective feedback was given to students based on their performance in the first round of the handwriting competition. The result shows that out of 240 students, 20 per cent of students got the best handwriting at the Hyderabad Institute of Excellence. Overall, 53 per cent of students showed improvement in their handwriting.
description: Internet Latent Corpus Journal, vol. 13 n.º 2 (2023)
Local density for two-dimensional one-component plasma
Creators: name: Bauerschmidt, Roland
name: Bourgade, Paul
name: Nikula, Miika
name: Yau, Horng-Tzer
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Physics (math-ph)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 82B05, 15B52

description: We study the classical two-dimensional one-component plasma of $N$ positively charged point particles, interacting via the Coulomb potential and confined by an external potential. For the specific inverse temperature $β=1$ (in our normalization), the charges are the eigenvalues of random normal matrices, and the model is exactly solvable as a determinantal point process. For any positive temperature, using a multiscale scheme of iterated mean-field bounds, we prove that the equilibrium measure provides the local particle density down to the optimal scale of $N^{o(1)}$ particles. Using this result and the loop equation, we further prove that the particle configurations are rigid, in the sense that the fluctuations of smooth linear statistics on any scale are $N^{o(1)}$.
Baccharis isabelae Soria & Zardini, Candollea
Creators: name: Chocarro, María Del Carmen Peña
name: Egea, Juana De
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Baccharis
Baccharis isabelae

description: Baccharis isabelae Soria & Zardini, Candollea 46(2): 537.
Shrub.
 Vouchers: Central: Hassler 11831 (BM, G); Hassler 11831a (BM, G); Hassler 361 (G). Cordillera: Hassler 2809 (BM, G); Osten & Rojas 8796 (G); Osten & Rojas 8797 (G); Soria & Ortiz 4247, type (CTES, FCQ, G, LP, MA, MO). Paraguarí: Hassler 305 (G). Unknown: Rojas 1305 (G); Rojas 1305a (G).
description: Published as part of Chocarro, María Del Carmen Peña & Egea, Juana De, 2018, Checklist of the endemic vascular plants of Paraguay, pp. 448-450 in Phytotaxa 384 (1) on pages 448-450, DOI: 10.11646/phytotaxa.384.1.1, http://zenodo.org/record/13725946
Non-Abelian $SU(3)_k$ anyons: inversion identities for higher rank face models
Creators: name: Frahm, Holger
name: Karaiskos, Nikos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The spectral problem for an integrable system of particles satisfying the fusion rules of $SU(3)_k$ is expressed in terms of exact inversion identities satisfied by the commuting transfer matrices of the integrable fused $A_2^{(1)}$ interaction round a face (IRF) model of Jimbo, Miwa and Okado. The identities are proven using local properties of the Boltzmann weights, in particular the Yang-Baxter equation and unitarity. They are closely related to the consistency conditions for the construction of eigenvalues obtained in the Separation of Variables approach to integrable vertex models.
description: 25 pages
title: Painless Visible Haematuria: An Algorithmic Approach to Diagnosis
Creators: name: Dulku, Gurjeet
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Urinary Tract / Bladder
subject: Oncology
subject: Ultrasound
subject: CT
subject: MR
subject: Cystography / Uretrography
subject: Instrumentation
subject: Cancer
subject: Blood

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: Any single episode of visible haematuria (VH) is significant and may be a sign of serious underlying disease, including malignancy. [1] Prompt diagnosis is essential and appropriate imaging strategies, based on risk stratification, are...
InSoLiTo project: The research software graph-based network from OpenEBench
Creators: name: Aguiló-Castillo, Sergi
name: Fernández, Jose M.
name: Gelpí, Josep Ll.
name: Capella-Gutiérrez, Salvador
Publisher: name: F1000 Research Limited
Year: 2022

description: InSoLiTo is a graph-based network of the co-usage of research software from the tools collection hosted by OpenEBench. Co-usage is understood as being cited in the same scientific publications. The initial aim of the project is to identify how bioinformatics tools relate to each other allowing to potentially infer analytical workflows commonly used in the literature. These results can be then used by research communities organizing scientific benchmarks on popular pipelines in their domains. Interestingly, this analysis can also be extended to include widely used databases and other relevant resources as part of those workflows.

 Data is freely accessible from a data portal (add URL) In the webpage, the user can interact with the graph network by filtering any bioinformatics’ tool stored in OpenEBench and see which other tools works with. Also, users can filter per year to see the evolution of the usage of other software in relation to the selected tool, and see which bioinformatics’ community it belongs to. Moreover, the inter- and intra-relationships between different branches of bioinformatics regarding its tools co-usage can be examined.

 This addition of OpenEBench will bring a new perspective of benchmarking and monitoring research software that will complement the existing capabilities of the platform.
A novel histopathological scoring system to distinguish urticarial vasculitis from chronic spontaneous urticaria
Creators: name: Puhl, Viktoria
name: Bonnekoh, Hanna
name: Scheffel, Jörg
name: Hawro, Tomasz
name: Weller, Karsten
name: Driesch, Peter Von Den
name: Röwert‐Huber, Hans‐Joachim
name: Cardoso, José
name: Gonçalo, Margarida
name: Maurer, Marcus
name: Krause, Karoline
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: chronische sponstane urtikaria
subject: endothelzellschwellung
subject: erythrozyten-extravasate
subject: fibrin
subject: histopathologie
subject: leukozytoklasie
subject: urtikariavaskulitis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Urticarial vasculitis (UV) is defined by long-lasting urticarial lesions combined with the histopathologic findings of leukocytoclastic vasculitis. As one of the major unmet needs in UV, diagnostic criteria are rather vague and not standardized. Moreover, there seems to be considerable overlap with chronic spontaneous urticaria (CSU), particularly for the normocomplementemic variant of UV. Therefore, this study aimed to develop a diagnostic scoring system that improves the histopathologic discrimination between UV and CSU. Methods: Lesional skin sections of patients with clinical and histopathologic diagnosis of UV (n = 46) and CSU (n = 51) were analyzed (blinded to the diagnosis) for the following pre-defined criteria: presence of leukocytoclasia, erythrocyte extravasation, fibrin deposits, endothelial cell swelling, ectatic vessels, blurred vessel borders, dermal edema, intravascular neutrophil, and eosinophil numbers and numbers of dermal neutrophils, macrophages and mast cells. Results: The greatest differences between UV and CSU samples were observed for leukocytoclasia (present in 76% of UV vs. 3.9% of CSU samples; p < 0.0001), erythrocyte extravasation (present in 41.3% of UV vs. 2.0% of CSU samples; p < 0.0001), and fibrin deposits (present in 27.9% of UV vessels vs. 9.7% of CSU vessels; p < 0.0001). Based on these findings, we developed a diagnostic score, the urticarial vasculitis score (UVS), which correctly assigned 37 of 46 cases of UV and 49 of 51 cases of CSU to the previously established diagnosis. Conclusion: Our results suggest that the UVS, a combined quantitative assessment of the three criteria leukocytoclasia, fibrin deposits and extravasated erythrocytes, distinguishes UV from CSU in skin histopathology. The UVS, if validated in larger patient samples, may help to improve the diagnostic approach to UV.
title: The Diagnostic Imaging Dilemmas of Suspected Pulmonary Embolism in Pregnancy: What Is the Current Evidence?
Creators: name: Dulku, Gurjeet
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Obstetrics (Pregnancy / birth / postnatal period)
subject: Pulmonary vessels
subject: Conventional radiography
subject: CT-Angiography
subject: Nuclear medicine conventional
subject: Decision analysis
subject: Embolism / Thrombosis
subject: Obstetrics

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To address the diagnostic dilemmas of imaging of pregnant patients with suspected pulmonary...
Preoperative medication use and development of postoperative delirium and cognitive dysfunction
Creators: name: Heinrich, Maria
name: Nottbrock, Anja
name: Borchers, Friedrich
name: Mörgeli, Rudolf
name: Kruppa, Jochen
name: Winterer, Georg
name: Slooter, Arjen J. C.
name: Spies, Claudia
name: BioCog Consortium
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: Emergence Delirium
subject: Mental Status and Dementia Tests
subject: Postoperative Cognitive Complications
subject: Potentially Inappropriate Medication List
subject: Preoperative Period
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Postoperative delirium (POD) and postoperative (neuro-)cognitive disorder (POCD) are frequent and serious complications after operations. We aim to investigate the association between pre-operative polypharmacy and potentially inappropriate medications and the development of POD/POCD in elderly patients. This investigation is part of the European BioCog project (www.biocog.eu), a prospective multicenter observational study with elderly surgical patients. Patients with a Mini-Mental State Examination score less than or equal to 23 points were excluded. POD was assessed up to 7 days after surgery using the Nursing Delirium Screening Scale, Confusion Assessment Method (for the intensive care unit [ICU]), and a patient chart review. POCD was assessed 3 months after surgery with a neuropsychological test battery. Pre-operative long-term medication was evaluated in terms of polypharmacy (≥5 agents) and potentially inappropriate medication (defined by the PRISCUS and European list of potentially inappropriate medications [EU(7)-PIM] lists), and associations with POD and POCD were analyzed using logistic regression analysis. Eight hundred thirty-seven participants were included for analysis of POD and 562 participants for POCD. Of these, 165 patients (19.7%) fulfilled the criteria of POD and 60 (10.7%) for POCD. After adjusting for confounders, pre-operative polypharmacy and intake of potentially inappropriate medications could not be shown to be associated with the development of POD nor POCD. We found no associations between pre-operative polypharmacy and potentially inappropriate medications and development of POD and POCD. Future studies should focus on the evaluation of drug interactions to determine whether patients benefit from a pre-operative adjustment.
A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA
Creators: name: Schaenzer, Adam J.
name: Wlodarchak, Nathan
name: Sauer, John-Demian
name: Drewry, David H.
name: Striker, Rob
name: Zuercher, William J.
name: Rose, Warren E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Bacterial signaling systems such as protein kinases and quorum sensing have become increasingly attractive targets for the development of novel antimicrobial agents in a time of rising antibiotic resistance. The family of bacterial Penicillin-binding-protein And Serine/Threonine kinase-Associated (PASTA) kinases is of particular interest due to the role of these kinases in regulating resistance to β-lactam antibiotics. As such, small-molecule kinase inhibitors that target PASTA kinases may prove beneficial as treatments adjunctive to β-lactam therapy. Despite this interest, only limited progress has been made in identifying functional inhibitors of the PASTA kinases that have both activity against the intact microbe and high kinase specificity. Here, we report the results of a small-molecule screen that identified GSK690693, an imidazopyridine aminofurazan-type kinase inhibitor that increases the sensitivity of the intracellular pathogen Listeria monocytogenes to various β-lactams by inhibiting the PASTA kinase PrkA. GSK690693 potently inhibited PrkA kinase activity biochemically and exhibited significant selectivity for PrkA relative to the Staphylococcus aureus PASTA kinase Stk1. Furthermore, other imidazopyridine aminofurazans could effectively inhibit PrkA and potentiate β-lactam antibiotic activity to varying degrees. The presence of the 2-methyl-3-butyn-2-ol (alkynol) moiety was important for both biochemical and antimicrobial activity. Finally, mutagenesis studies demonstrated residues in the back pocket of the active site are important for GSK690693 selectivity. These data suggest that targeted screens can successfully identify PASTA kinase inhibitors with both biochemical and antimicrobial specificity. Moreover, the imidazopyridine aminofurazans represent a family of PASTA kinase inhibitors that have the potential to be optimized for selective PASTA kinase inhibition.
Sonnenfleckenzeichnung Nr. 221.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.09.2008, 07:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 1.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 65.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.03.2008, 09:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2008

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Global Parton Distributions for the LHC Run II
Creators: name: Ball, Richard D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We review the next generation global PDF sets: NNPDF3.0, MMHT14 and CT14. We describe the global datasets, particularly the new data from LHC Run 1, recent developments in QCD theory and PDF methodology, improvements in combination and delivery, and future prospects for parton determination at Run 2.
description: 15 pages, 11 figures; talk given at La Thuile, 3rd March 2015; updated references
title: Pulmonary Amyloidomas - An Unusual Cause Mimicking Lung Cancer
Creators: name: Rao, Akshay
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2016
Subjects: subject: Respiratory system
subject: CT
subject: PET
subject: Education
subject: Ablation procedures
subject: Cancer
subject: Education and training

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: Presentation, radiological and histological findings of this uncommon...
Short-range correlations and their implications for isospin-dependent modification of nuclear quark distributions
Creators: name: Arrington, John
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The past decade has provided a much clearer picture of the structure of high-momentum components in nucleons, associated with hard, short-distance interactions between pairs of nucleons. Recent Jefferson Lab data on light nuclei suggest a connection between these so-called 'short-range correlations' and the modification of the quark structure of nucleons in the nuclear environment. In light of this discovery that the detailed nuclear structure is important in describing the nuclear quark distributions, we examine the potential impact of the isospin-dependent structure of nuclei to see at what level this might yield flavor-dependent effects in nuclear quark distributions.
description: 10 pages, 2 figures, proceedings from the 21st international conference on few-body physics
Forecast of surface layer meteorological parameters at Cerro Paranal with a mesoscale atmospherical model
Creators: name: Lascaux, Franck
name: Masciadri, Elena
name: Fini, Luca
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: This article aims at proving the feasibility of the forecast of all the most relevant classical atmospherical parameters for astronomical applications (wind speed and direction, temperature) above the ESO ground-base site of Cerro Paranal with a mesoscale atmospherical model called Meso-Nh. In a precedent paper we have preliminarily treated the model performances obtained in reconstructing some key atmospherical parameters in the surface layer 0-30~m studying the bias and the RMSE on a statistical sample of 20 nights. Results were very encouraging and it appeared therefore mandatory to confirm such a good result on a much richer statistical sample. In this paper, the study was extended to a total sample of 129 nights between 2007 and 2011 distributed in different parts of the solar year. This large sample made our analysis more robust and definitive in terms of the model performances and permitted us to confirm the excellent performances of the model. Besides, we present an independent analysis of the model performances using the method of the contingency tables. Such a method permitted us to provide complementary key informations with respect to the bias and the RMSE particularly useful for an operational implementation of a forecast system.
description: 20 pages, 8 figures, 18 tables, published in MNRAS