Associations Between Carotid-Femoral and Brachial-Femoral Pulse Wave Velocity with Sleeping Regularity in College Based Young Adults.
Creators: name: Paul Ahern
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: (ABSTRACT UPLOADED ABOVE IN PDF FORMAT FOR BETTER QUALITY)


Associations Between Carotid-Femoral and Brachial-Femoral Pulse Wave Velocity with 
Sleeping Regularity in College Based Young Adults.
Cardiovascular disease (CVD) is the leading cause of mortality globally 1. Sleep is intrinsically 
related to health in humans. Lack of sleep time2
, quality2
, and consistency3 have been linked to 
increasing risk of CVD. Pulse wave velocity is a proxy of arterial stiffness. Arterial stiffness is 
indicative of blood vessel health and aging4
. Sleep irregularity is associated with higher risk of CVD 
in older adults3 and is associated with future predictors of CVD like microvascular dysfunction5
, 
inflammation6
, and adiposity7
in younger adults. The relationship between sleep regularity and 
pulse wave velocity has not been thoroughly investigated. 
In an initial visit We examined cardiometabolic profiles in 105 participants, while also tracking 
various other measures for the following 7 days. We used the Vicorder-oscillometry system to 
measure pulse wave velocity and used the SleepScoreMax device to measure sleep. We performed 
a multiple linear regression analysis using R-studio programming software. Sleep regularity as 
measured via three different calculations served as our exposure and two different measures of 
pulse wave velocity served as our outcome.
Our regression analysis did not yield a significant relationship in any of our models. None of our 
beta coefficients were prominent enough to suggest practical. Use in a clinical setting. 
Further investigation is needed in order to establish a relationship between these two variables. If 
performing this analysis again refinement of protocol is recommended.
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Am Coll Cardiol 75, 991–999 (2020).
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1056 (2022).
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Brain Behav Immun Health 13, (2021).
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in adolescence. Obesity 31, 597–614 (2023)