Additional file 1 of Time spent above optimal cerebral perfusion pressure is not associated with failure to improve in outcome in traumatic brain injury
Creators: name: Stein, Kevin Y.
name: Froese, Logan
name: Gomez, Alwyn
name: Sainbhi, Amanjyot Singh
name: Vakitbilir, Nuray
name: Ibrahim, Younis
name: Islam, Abrar
name: Marquez, Izabella
name: Amenta, Fiorella
name: Bergmann, Tobias
name: Zeiler, Frederick A.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Molecular Biology
Neuroscience
Science Policy

description: Additional file 1: Appendix A. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Alive/Dead and Favorable/Unfavorable at 1 month. Appendix B. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Alive/Dead and Favorable/Unfavorable at 3 months. Appendix C. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Alive/Dead and Favorable/Unfavorable at 6 months. Appendix D. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Improved/Not Improved (3–6 months). Appendix E. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Improved/Not Improved (1–3 months) with Those Who Died (GOSE = 1) Removed. Appendix F. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Improved/Not Improved (3–6 months) with Those Who Died (GOSE = 1) Removed. Appendix G. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Improved/Not Improved (1–6 months) with Those Who Died (GOSE = 1) Removed. Appendix H. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Improved/Not Improved (1–3 months) with Patients Trichotomized by Age. Appendix I. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Improved/Not Improved (3–6 months) with Patients Trichotomized by Age. Appendix J. Mann–Whitney U/Chi-Square Testing of Physiologic and Demographic Data for Improved/Not Improved (1–6 months) with Patients Trichotomized by Age. Appendix K. Histograms Comparing Improved and Not Improved Patients for % time with ΔCPPopt above/below 10 mmHg. Appendix L. Univariate Models of Cerebrovascular Reactivity Measures for Transition in Outcome with Those Who Died (GOSE = 1) Removed. Appendix M. Univariate Models of Cerebrovascular Reactivity Measures for Transition in Outcome with Patients Trichotomized by Age. Appendix N. Multivariable Models of Cerebrovascular Reactivity Measures + IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg for Transition in Outcome from 1 to 3 months. Appendix O. Multivariable Models of Cerebrovascular Reactivity Measures + IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg for Transition in Outcome from 3 to 6 months. Appendix P. Multivariable Models of Cerebrovascular Reactivity Measures + IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg for Transition in Outcome from 1 to 6 months. Appendix Q. Multivariable Models of Cerebrovascular Reactivity Measures + IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg for Transition in Outcome from 1 to 3 months with Those Who Died (GOSE = 1) Removed. Appendix R. Multivariable Models of Cerebrovascular Reactivity Measures + IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg for Transition in Outcome from 3 to 6 months with Those Who Died (GOSE = 1) Removed. Appendix S. Multivariable Models of Cerebrovascular Reactivity Measures + IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg for Transition in Outcome from 1 to 6 months with Those Who Died (GOSE = 1) Removed. Appendix T. Multivariable Models of Cerebrovascular Reactivity Measures for Transition in Outcome from 1 to 3 months with Patients Trichotomized by Age. Appendix U. Multivariable Models of Cerebrovascular Reactivity Measures for Transition in Outcome from 3 to 6 months with Patients Trichotomized by Age. Appendix V. Multivariable Models of Cerebrovascular Reactivity Measures for Transition in Outcome from 1 to 6 months with Patients Trichotomized by Age. Appendix W. Added Variance in Transition in Outcome of Cerebrovascular Reactivity Measures Over IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg with Those Who Died (GOSE = 1) Removed. Appendix X. Added Variance in Transition in Outcome of Cerebrovascular Reactivity Measures Over IMPACT Core ± CT ± ICP &gt; 20 or 22 mmHg with Patients Trichotomized by Age. Appendix Y. Extended Discussion. Appendix Z. Graphical Illustration of the Relationships Between ICP and Cerebrovascular Reactivity