cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Accuracy of Pre-Operative MRI Staging and Assessment of Tumour Response following Chemoradiation in Rectal Cancer: a DGH experience
Creators: name: Teoh, Suliana
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Colon
subject: Oncology
subject: MR
subject: Radiation therapy / Oncology
subject: Staging
subject: Chemotherapy
subject: Neoplasia

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: To evaluate the accuracy of magnetic resonance imaging (MRI) staging of rectal cancer compared to histology and assess tumour response following chemoradiation within a district general hospital. I ntroduction Locally advanced rectal cancer is...
(Un)kulturlandschaften der NS-Zeit
Creators: name: Bollacher, Christian
name: Hausmair, Barbara
name: Dészi, Attila
Publisher: name: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege
Year: 2022

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 51 Nr. 2 (2022)
Arlaud & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1820

description: Ort: Konstantinopel (Istanbul)
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Historische Steinbrüche als Relikte der Kulturlandschaft
Creators: name: Werner, Wolfgang
Publisher: name: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege
Year: 2022

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 51 Nr. 2 (2022)
title: Neuroimaging in FXTAS. Can we predict conversion of premutation carriers?
Creators: name: Gómez-Anson, Beatriz
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Neuroradiology brain
subject: MR

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: 1-To investigate if 3T MRI markers can differentiate FXTAS* from non-FXTAS subjects, and thus be potentially useful in predicting conversion of premutation carriers to FXTAS. 2-To evaluate the relationship between MRI markers and...
Dutilh, D. P., père, fils & Co. (Dutilh & Co.)
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1820

description: Ort: Smyrna
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Classication of Itchgrass Using Morphological Traits and AFLP Techniques
Creators: name: Sunyata  Meksawat
name: Tosapon  Pornprom
Publisher: name: Department of Agriculture
Year: 2012
Subjects: หญ้าโขย่ง
ลักษณะทางสัณฐานวิทยา
เทคนิค AFLP

description: Thai Agricultural Research Journal, 30, 1, 39-52
Bonnal, Frères & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1825

description: Ort: Smyrna
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Additional file 6 of Earbox, an open tool for high-throughput measurement of the spatial organization of maize ears and inference of novel traits
Creators: name: Oury, V.
name: Leroux, T.
name: Turc, O.
name: Chapuis, R.
name: Palaffre, C.
name: Tardieu, F.
name: Prado, S. Alvarez
name: Welcker, C.
name: Lacube, S.
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 6 Fig. S6. Output of the estimation of the number of cohorts along the perpendicular ear axis. For each position along the ear diameter (x), the number of cohorts (y) is calculated for each ear shown in Fig. 5 with the methodology presented in Supplementary Fig. S3. Black line, ear with white grains; red line, ear with vine grains; golden line, aborted ear with yellow grains. Dotted lines represent the maximum number of cohorts for each curve. The maximum number of cohorts is used as the output of the routine workflow and its average over the 6 ear sides is used for the correlation in Fig. 6. Each curve represents data from a single image/ear side.
Cloning and Characterization of Cyclophilin Gene from Sorghum bicolor (L.) Moench and Its Transformation into Tobacco Plant
Creators: name: Suphwadee Ngorian
name: Payungsak  Rauyaree
name: Karsedis Distabanjong
name: Chayanit  Distbanjong
name: Hathairat  Urairong
Publisher: name: Department of Agriculture
Year: 2012
Subjects: ยีนไซโคลฟิลิน
ข้าวฟ่าง
การโคลนและวิเคราะห์ยีน
การถ่ายฝากยีน
ยาสูบ

description: Thai Agricultural Research Journal, 30, 1, 2-22
Burnens & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1825

description: Ort: Smyrna
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
title: Diffusion kurtosis may characterize intracranial tumours
Creators: name: Van Westen, Danielle
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Tissue characterisation
subject: MR-Diffusion/Perfusion
subject: Neuroradiology brain

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: To investigate if the diffusion kurtosis, which is the non-Gaussian component of the diffusion and reflects the microstructural complexity of tissue [1], can differentiate between intracranial...
Polycyrtus pallidibalteatus Cameron 1885
Creators: name: Khalaim, Andrey I.
name: Kasparyan, Dmitri R.
name: López-Ortega, Maurilio
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Polycyrtus
Polycyrtus pallidibalteatus

description: 43. Polycyrtus pallidibalteatus Cameron, 1885
References. Kasparyan & Ruíz-Cancino 2008: 296.
Material examined. Veracruz: 1 ♀ (UNAM) Xalapa, N 19°30′, W 96°55′, 1279 m, Malaise trap, 20.VIII– 17.IX.2015, coll. M. López-Ortega.
Distribution. Mexico (Oaxaca, Tabasco, Veracruz), Costa Rica.
description: Published as part of Khalaim, Andrey I., Kasparyan, Dmitri R. & López-Ortega, Maurilio, 2018, New records and descriptions of Ichneumonidae (Hymenoptera) from Mexico, pp. 1-30 in Zootaxa 4486 (1) on page 14, DOI: 10.11646/zootaxa.4486.1.1, http://zenodo.org/record/1437993
title: CT anatomy of the sphenoid bone
Creators: name: Fakhfakh, Khaled
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Head and neck
subject: Anatomy
subject: CT-High Resolution
subject: Computer Applications-Virtual imaging
subject: Computer Applications-3D
subject: Trauma

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: To review detailledCTanatomyofthesphenoidbone To illustrate thisanatomywithCTMPR and 3D...
Glavany, Jacques, Fils & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1825

description: Ort: Konstantinopel (Istanbul)
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Comparative Characteristic and Storage Period Egg of Erisilk (Philosamia ricini Boisduval)
Creators: name: Tanakij Thamee
name: Tanpporn  Sinlapachai
name: Wanthana Thonglem
name: Prayad Teekawong
Publisher: name: Department of Agriculture
Year: 2013
Subjects: ไหมป่าอีรี่
คุณลักษณะพันธุ์
ระยะการเก็บรักษา
Eri sikl
comparative characteristic
storage period

description: Thai Agricultural Research Journal, 31, 3, 307-320
KANOB XOM-ASHYOSINI QABUL QILISH VA QAYTA ISHLASH TEXNOLOGIYASI
Creators: name: Qabulov, Ibrohim
name: Abdiqulova, Lola
Publisher: name: Zenodo
Year: 2024

description: Qishloq xo‘jaligini isloh qilish, Kanop tayyorlash texnalogiyasi haqida ma’lumot berilgan, Tolali o’simliklar to’qishga yaroqli tola beradi, Oziq-ovqat xavfsizligining to‘rt tarkibiy qismlari (oziq-ovqatning mavjud, Kanop poyasida 17-18% to’qishga yaroqli tola hosil qiladi, Kanoppoya bir-biri bilan yondosh turgan alohida hujayralardan iborat bo’lgan murakkab strukturali o’simlik.
Inhalt
Creators: name: Redaktion, Die
Publisher: name: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege
Year: 2022

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 51 Nr. 2 (2022)
title: Cranial nerve injury after skull fracture
Creators: name: Fakhfakh, Khaled
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Trauma
subject: Cerebral palsy
subject: CT-High Resolution
subject: Head and neck

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: Recognize skull fractures associated with cranial nerves...
Comparison of Methods of Dry Rubber Content Determination and Correlation between Dry Rubber Content and Biochemical Compositions and Plant Nutrients in Rubber Latex
Creators: name: Nuttapong Srisombut
name: Jumpen Onthong
name: Apichat  Kuekorboon
Publisher: name: Department of Agriculture
Year: 2013
Subjects: เนื้อยางแห้ง
องค์ประกอบทางชีวเคมี
ธาตุอาหารพืช
น้ำยางพารา
dry rubber content
biochemical composition
plant nutrient
rubber latex

description: Thai Agricultural Research Journal, 31, 2, 123-138
title: Effects of ageing on dermal echogenicity assessed by high-frequency skin ultrasonography
Creators: name: Lupsor-Platon, Monica
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Geriatrics
subject: Ultrasound
subject: Technology assessment
subject: Tissue characterisation

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: During the last years, skin ageing has become an area of increasing research interest. A precise and non-invasive quantification of ageing is essential for in vivo studies in skin gerontology and several techniques have been proposed for this...
Photocryptus pachymenae
Creators: name: Khalaim, Andrey I.
name: Kasparyan, Dmitri R.
name: López-Ortega, Maurilio
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Photocryptus
Photocryptus pachymenae

description: 44. Photocryptus pachymenae (Cresson, 1874)
References. Kasparyan & Ruíz-Cancino 2008: 340. Aguiar & Santos 2009: 52. Material examined. Morelos: 1 ♀ (UAEM), Tepalzingo, N of Estación Biológica El Limón, N 18.547, W 98.935, 1360 m, 1.VIII.2007, coll. J.G. Martinez Hernández. Veracruz: 1 ♂ (EMEC), Cotaxtla, Cotaxtla Exp. Station, 17.VII.1962, coll. D.H. Janzen, UC Berkeley EMEC 735326.
Distribution. Mexico (Chiapas, Jalisco, Morelos, Nayarit, Sinaloa, Tamaulipas, Veracruz, Yucatán), Nicaragua, Costa Rica, Panama, Guyana.
Biology. Recorded as parasitoid of Pachymenes sp. (Vespidae) in Mexico and Sceliphron fistularium (Dahlbom) (Sphecidae) in Panama.
description: Published as part of Khalaim, Andrey I., Kasparyan, Dmitri R. & López-Ortega, Maurilio, 2018, New records and descriptions of Ichneumonidae (Hymenoptera) from Mexico, pp. 1-30 in Zootaxa 4486 (1) on pages 14-15, DOI: 10.11646/zootaxa.4486.1.1, http://zenodo.org/record/1437993
Additional file 7 of Earbox, an open tool for high-throughput measurement of the spatial organization of maize ears and inference of novel traits
Creators: name: Oury, V.
name: Leroux, T.
name: Turc, O.
name: Chapuis, R.
name: Palaffre, C.
name: Tardieu, F.
name: Prado, S. Alvarez
name: Welcker, C.
name: Lacube, S.
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 7 Fig. S7. Illustration of the cohort classification algorithm. Grains are classified in cohorts (each identified by a color) by scanning the ear from bottom to top starting with the lowest grain (bold black dots on the barycenter). The classification is done sequentially, one cohort at a time. For each cohort, grains whose barycenter lie within a specific range of pixels along the main axis of the ear are classified into a common cohort, and removed for the rest of the classification process. Black dots: grain barycenter’s. Colors: grains classified in the same cohort.
Hayes, La Fontaine & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1825

description: Ort: Konstantinopel (Istanbul)
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
title: Incidental findings on abdominal CT scans
Creators: name: Djosev, Marija
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Abdomen
subject: CT
subject: Statistics
subject: FOS: Mathematics
subject: Haemangioma
subject: Aneurysms

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Incidental findings on abdominal CT scans are very common. Many of them have little or no clinical significance, such as hepatic cysts and renal cysts, stones or calcifications. However, many incidental findings are clinically significant. Some of...
Myocyte Enhancer Factor 2A (MEF2A) Defines Oxytocin-Induced Morphological Effects and Regulates Mitochondrial Function in Neurons
Creators: name: Meyer, Magdalena
name: Kuffner, Kerstin
name: Winter, Julia
name: Neumann, Inga D.
name: Wetzel, Christian H.
name: Jurek, Benjamin
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: TRANSCRIPTION; RECEPTOR; CALCINEURIN; EXPRESSION; ACTIVATION; CYTOSKELETAL; VASOPRESSIN; MOLECULES; BEHAVIOR; PROTEIN; oxytocin; morphology; neurite outgrowth; neurite retraction; autism; MEF2A; CRISPR-Cas; hyperconnectivity
subject: 590 Tiere (Zoologie)
subject: 610 Medizin

description: The neuropeptide oxytocin (OT) is a well-described modulator of socio-emotional traits, such as anxiety, stress, social behavior, and pair bonding. However, when dysregulated, it is associated with adverse psychiatric traits, such as various aspects of autism spectrum disorder (ASD). In this study, we identify the transcription factor myocyte enhancer factor 2A (MEF2A) as the common link between OT and cellular changes symptomatic for ASD, encompassing neuronal morphology, connectivity, and mitochondrial function. We provide evidence for MEF2A as the decisive factor defining the cellular response to OT: while OT induces neurite retraction in MEF2A expressing neurons, OT causes neurite outgrowth in absence of MEF2A. A CRISPR-Cas-mediated knockout of MEF2A and retransfection of an active version or permanently inactive mutant, respectively, validated our findings. We also identified the phosphatase calcineurin as the main upstream regulator of OT-induced MEF2A signaling. Further, MEF2A signaling dampens mitochondrial functioning in neurons, as MEF2A knockout cells show increased maximal cellular respiration, spare respiratory capacity, and total cellular ATP. In summary, we reveal a central role for OT-induced MEF2A activity as major regulator of cellular morphology as well as neuronal connectivity and mitochondrial functioning, with broad implications for a potential treatment of disorders based on morphological alterations or mitochondrial dysfunction.
title: Vacuum phenomenon in computed tomography - fluid signal in MRI: a correlative study of degenerative disc disease
Creators: name: D'Anastasi, Melvin
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Neuroradiology spine
subject: MR
subject: CT
subject: Musculoskeletal spine

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Intradiscal vacuum phenomenon is a common finding in computed tomography (CT) of degenerative lumbar disc disease. Intradiscal fluid in MRI is rare in osteochondrosis and always raises the suspicion of spondylodiscitis. Our aim was to correlate: 1)...
Burnens & Co
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1826

description: Ort: Smyrna
description: Verzeichnung=Description=Inventaire 05.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
title: Oxygen-enhanced MRI (oeMRI) in tumour masses in patients with bronchial carcinoma - feasibility and MRI/CT consensus correlation
Creators: name: Maxien, Daniel
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Lung
subject: Respiratory system
subject: Oncology
subject: MR-Functional imaging
subject: MR

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: The success of the therapy in bronchial carcinomas highly depends on the vitality of the tumor mass. Common oeMRI is used to assess the lung parenchyma ( 1-6 ). It is known that tumor masses also show a signal increase during oxygen inhalation in...
Chalcogen bonds formed by protein sulfur atoms in proteins. A survey of high-resolution structures deposited in the protein data bank
Creators: name: Carugo, Oliviero Italo
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: Computational Biology

description: The presence of chalcogen bonds in native proteins was investigated on a non-redundant and high-resolution (≤ 1 Angstrom) set of protein crystal structures deposited in the Protein Data Bank. It was observed that about one half of the sulfur atoms of methionines and disulfide bridges from chalcogen bonds with nucleophiles (oxygen and sulfur atoms, and aromatic rings). This suggests that chalcogen bonds are a non-bonding interaction important for protein stability. Quite numerous chalcogen bonds involve water molecules. Interestingly, in the case of disulfide bridges, chalcogen bonds have a marked tendency to occur along the S-S bond extension rather than along the C-S bond extension. Additionally, it has been observed that closer residues have a higher probability of being connected by a chalcogen bonds, while the secondary structure of the two residues connected by a chalcogen bond do not correlate with its formation. Communicated by Ramaswamy H. Sarma
Amydraulax mexicana Kasparyan & Ruiz-Cancino 2003
Creators: name: Khalaim, Andrey I.
name: Kasparyan, Dmitri R.
name: López-Ortega, Maurilio
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Amydraulax
Amydraulax mexicana

description: 45. Amydraulax mexicana Kasparyan & Ruíz-Cancino, 2003
(Fig. 14)
References. Kasparyan & Ruíz-Cancino 2003: 441.
Material examined. Hidalgo: 1 ♀ (UAT) 8 km N of Pachuca de Soto, National Park El Chico, N 20°11.4′, W 98°44.55′, 2800–2900 m, 18–22.XII.2014, coll. A.I. Khalaim.
Distribution. Mexico (Tamaulipas, Coahuila, * Hidalgo).
description: Published as part of Khalaim, Andrey I., Kasparyan, Dmitri R. & López-Ortega, Maurilio, 2018, New records and descriptions of Ichneumonidae (Hymenoptera) from Mexico, pp. 1-30 in Zootaxa 4486 (1) on page 15, DOI: 10.11646/zootaxa.4486.1.1, http://zenodo.org/record/1437993
title: Cholangiocarcinoma: appearances and mimics
Creators: name: Cardenas Valencia, Cristina
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Neoplasia
subject: Computer Applications-Detection, diagnosis
subject: MR
subject: CT
subject: Biliary Tract / Gallbladder

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: •Review the features of cholangiocarcinoma in terms of epidemiologic and pathologic considerations, risk factors, classification types and prognosis. •Exhibit the spectrum of presentation of cholangiocarcinoma in CT and MR . •Show CT and MR...
Enhancing Student Teachers’ Learning Engagement and Classroom Action Research Skills through Active Learning with Online Classroom
Creators: name: Kanit Sriklaub
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: active learning
online classroom
learning engagement
classroom action research skills

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 1-17
EOSC-Pillar Use case 1 - Defining procedures and services to enforce data provenance for thematic communities and beyond
Creators: name: Cozzini, Stefano
name: Osmenaj, Elda
name: Antonio, Fabrizio
name: Kulüke, Marco
name: Kindermann, Stephan
name: Drago, Federico
name: Savini, Gianluca
Publisher: name: Zenodo
Year: 2022
Subjects: EOSC
Open Science
Climate Science
Nanoscience
Materials Science

description: Due to data exploration complexity, provenance management is a key component in order to guarantee scientific data discovery, reproducibility and results interpretation. Provenance management should be able to define a set of metadata able to capture the derivation history of any stored data, including the original raw data sources, the intermediate data products and the steps that were applied to produce them. To enable a well-defined data provenance in the scientific experiments workflow, from data production to data usage, this task will: elaborate cross-domain, FAIR-oriented procedures and recommendations to enforce data provenance by taking into account needs coming from various communities such as nanoscience/soft matter, material science and climate change in the field of environmental science; implement these procedures and recommendations by developing the proper adaptations/extensions on top of existing scientific data services, made available by the participating partners at national level. Learn more
Bilanz-Buch Schrägband AG Basel
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1928

description: Deutsch
description: Verzeichnung=Description=Inventaire 02.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Additional file 8 of Earbox, an open tool for high-throughput measurement of the spatial organization of maize ears and inference of novel traits
Creators: name: Oury, V.
name: Leroux, T.
name: Turc, O.
name: Chapuis, R.
name: Palaffre, C.
name: Tardieu, F.
name: Prado, S. Alvarez
name: Welcker, C.
name: Lacube, S.
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 8 Fig. S8. Comparison of Earbox (y) and reference (x) data. (A) Number of grains per cohort in the basal third. (B) Number of grains per cohort in the apical third. (C) Length of the basal aborted zone in centimeters. (D) Length of the apical aborted zone in centimeters. Green dots: ears from biological diversity panel; red dots: ears from environmental diversity panel. Empty red dots: scattered ears of the environmental diversity panel (Fig.3B). Grey line: bisector line. Black line: linear regression of data. R²: correlation coefficient between x and y values, RMSE: root mean square error, n: number of observations in each graph.
Personalkontrolle Heimarbeiter
Creators: name: Senn und Co. AG
Publisher: name: [s.n.]
Year: 1906

description: Enthält: Verzeichnis der Heimarbeiter und Fergger, welche Heimarbeitsaufträge annehmen
description: Darin: Einzelne lose Einlage
description: Archivalienart: Druckschrift, Manuskript
description: Deutsch
description: Verzeichnung=Description=Inventaire 02.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Evaluation of potential bacterial protease inhibitor properties of selected hydroxyquinoline derivatives: an in silico docking and molecular dynamics simulation approach
Creators: name: Riaz, Faiza
name: Hossain, Md. Sanower
name: Roney, Miah
name: Ali, Yousaf
name: Qureshi, Saira
name: Muhammad, Riaz
name: Moshawih, Said
name: Hamid, Shafida Abd
name: Seidel, Veronique
name: Rashid, Haroon ur
name: Ming, Long Chiau
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Antimicrobial drug resistance (AMR) is a severe global threat to public health. The increasing emergence of drug-resistant bacteria requires the discovery of novel antibacterial agents. Quinoline derivatives have previously been reported to exhibit antimalarial, antiviral, antitumor, antiulcer, antioxidant and, most interestingly, antibacterial properties. In this study, we evaluated the binding affinity of three newly designed hydroxyquinolines derived from sulfanilamide (1), 4-amino benzoic acid (2) and sulfanilic acid (3) towards five bacterial protein targets (PDB ID: 1JIJ, 3VOB, 1ZI0, 6F86, 4CJN). The three derivatives were designed considering the amino acid residues identified at the active site of each protein involved in the binding of each co-crystallized ligand and drug-likeness properties. The ligands displayed binding energy values with the target proteins ranging from −2.17 to −8.45 kcal/mol. Compounds (1) and (3) showed the best binding scores towards 1ZI0/3VOB and 1JIJ/4CJN, respectively, which may serve as new antibiotic scaffolds. Our in silico results suggest that sulfanilamide (1) or sulfanilic acid (3) hydroxyquinoline derivatives have the potential to be developed as bacterial inhibitors, particularly MRSA inhibitors. But before that, it must go through the proper preclinical and clinical trials for further scientific validation. Further experimental studies are warranted to explore the antibacterial potential of these compounds through preclinical and clinical studies. Communicated by Ramaswamy H. Sarma
Chirotica thyridopteryx
Creators: name: Khalaim, Andrey I.
name: Kasparyan, Dmitri R.
name: López-Ortega, Maurilio
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Chirotica
Chirotica thyridopteryx

description: 46. Chirotica thyridopteryx (Riley, 1869)
(Figs 15, 16)
References. Carlson 1979: 395.
Remarks. The species was only mentioned from Mexico in the catalogue by Carlson (1979) with no details on its distribution in Mexico.
Material examined. Jalisco: 1 ♀ (EMEC) Biological Station Chamela, at lights, 23–31.VII.1990, coll. Chemsak, UC Berkeley EMEC 735335.
Distribution. USA (many localities), Mexico (* Jalisco).
Biology. Reared from species of Lepidoptera genera Astala Davis, Cryptothelea Duncan & Westwood, Oiketicus Guilding and Thyridopteryx Stephens (Psychidae), Grapholita Treitschke (Tortricidae) and Orgyia Ochsenheimer (Erebidae). Also recorded as hyperparasitoid in the ichneumonid genera Iseropus Förster and Itoplectis Förster (Hymenoptera: Ichneumonidae).
description: Published as part of Khalaim, Andrey I., Kasparyan, Dmitri R. & López-Ortega, Maurilio, 2018, New records and descriptions of Ichneumonidae (Hymenoptera) from Mexico, pp. 1-30 in Zootaxa 4486 (1) on page 15, DOI: 10.11646/zootaxa.4486.1.1, http://zenodo.org/record/1437993
title: MDCT imaging of Borderline Resectable Pancreatic cancers: A Pictorial Essay
Creators: name: Arya, Supreeta
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Neoplasia
subject: CT
subject: Pancreas

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: Borderline resectable tumors ( BRT) of the pancreas are a recently described entity that are likely to benefit from neoadjuvant therapy prior to surgery. AIMS-- To make radiologists aware about this new subset of pancreatic tumors called borderline...
The Study of Using Research-based Approach Associated with Lesson Study to Enhance Students’ Thinking Skills
Creators: name: Kanyarat Cojorn
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: analytical thinking
creative thinking
higher order thinking

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 18-32
"Décompte du Compte de Réserve"
Creators: name: Senn und Co. AG
Publisher: name: [s.n.]
Year: 1907

description: Vs. E 5-8??
description: Französisch
description: Verzeichnung=Description=Inventaire 02.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Additional file 9 of Earbox, an open tool for high-throughput measurement of the spatial organization of maize ears and inference of novel traits
Creators: name: Oury, V.
name: Leroux, T.
name: Turc, O.
name: Chapuis, R.
name: Palaffre, C.
name: Tardieu, F.
name: Prado, S. Alvarez
name: Welcker, C.
name: Lacube, S.
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 9 Fig. 9. Examples of grain dimensions as a function of cohort and position along the ear across 9 contrasting ears. Each point represents the average dimension of all grains classified in the same cohort (Fig. 5P, 5Q, 5R) across the 6 sides (images) of the ear. Red dots, average grain height in centimeters. Green dots, average grain width in centimeters. Error bars, standard deviation. Errors for position from ear base are shown but are smaller than the dots.
title: Renal epithelioid angiomyolipoma: A little known lethal variant
Creators: name: Halls, James
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: MR
subject: CT
subject: Kidney

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: Learning Objectives To describe the background of tuberous sclerosis and classic renal angiomyolipomas. To describe the recently described rare entity of renal epithelioid angiomyolipoma and present imaging features through case illustration and...
The Development of Tenth Graders’ Scientific Reasoning Ability through Argument-Driven Inquiry in Biology Course
Creators: name: Ilada Somparn
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: scientific reasoning
argument-driven inquiry
good teaching practice

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 33-49
Senn & Co. AG Seidenpreise
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1900

description: Darin: Seiden-Notizen (Büchlein, undatiert; ursprünglich Bestandteil der unsystematischen Sammlung zur Geschichte von Familie und Firma), einzelne Beilagen
description: Originaltitel «S&Cie Seidenpreise 4»
description: Deutsch, Französisch
Ethelurgus annulicornis Kasparyan & Ruiz-Cancino 2000
Creators: name: Khalaim, Andrey I.
name: Kasparyan, Dmitri R.
name: López-Ortega, Maurilio
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Ethelurgus
Ethelurgus annulicornis

description: 47. Ethelurgus annulicornis Kasparyan & Ruíz-Cancino, 2000
References. Kasparyan & Ruíz-Cancino 2000: 58.
Material examined. Veracruz: 1 ♀ (UNAM) Xalapa, N 19°30′, W 96°55′, 1279 m, Malaise trap, 2–20.X. 2015, coll. M. López-Ortega.
Distribution. Mexico (Tamaulipas, * Veracruz).
description: Published as part of Khalaim, Andrey I., Kasparyan, Dmitri R. & López-Ortega, Maurilio, 2018, New records and descriptions of Ichneumonidae (Hymenoptera) from Mexico, pp. 1-30 in Zootaxa 4486 (1) on page 15, DOI: 10.11646/zootaxa.4486.1.1, http://zenodo.org/record/1437993
Control of Major Insect Pests for Pummelo cv. Tubtim Siam
Creators: name: Wiriya Prajimpan
name: Thapanee Thongboon
name: Arporn Kongisro
name: Phaibun Priapying
Publisher: name: Department of Agriculture
Year: 2014
Subjects: ส้มโอพันธุ์ทับทิมสยาม
หนอนชอนใบส้ม
เพลี้ยไฟพริก
สารฆ่าแมลง

description: Thai Agricultural Research Journal, 32, 3, 308-318
Comprehensive in silico screening of flavonoids against SARS-CoV-2 main protease
Creators: name: Moezzi, Maryam Sadat
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: In the current pandemic caused by the new coronavirus (SARS-CoV-2), computational drug discovery can play an essential role in finding potential therapeutic agents. Thanks to its anti-viral, antibacterial, and anti-inflammatory properties, sage (Salvia officinalis) is used in traditional medicine. In this study, drugs proposed against COVID-19, including Lopinavir, Remdesivir, Favipiravir, and main flavonoids of sage, were docked favorably against novel coronavirus main protease. Molecular docking findings indicate that Rutin, Luteolin-7-glucoside, Apigenin, and Hispidulin make strong interactions with better binding affinity than selected commercial drugs in the study. But Rutin is the only flavonoid that makes strong hydrogen bond interactions with catalytic dyad and crucial Mpro residues and has more binding affinity than protease inhibitor PF-07321332 as an oral antiviral (PAXLOVID™). Further analysis of Molecular Dynamics and MM-PBSA predicted that chosen ligands could form stable complexes with the main protease. Also, ADMET analysis shows that main flavonoids are expected to have appropriate pharmacokinetic and no toxic properties. The results of the in silico study suggest that Salvia officinalis as a rich source of potent anti-coronavirus flavonoids may play a significant role in counteracting the replication of SARS-CoV-2. Communicated by Ramaswamy H. Sarma
Berechnungen
Creators: name: Senn und Co. AG
Publisher: name: [s.n.]
Year: 1900

description: Enthält: Berechnungen Seidenpreise länderspezifisch, webtechnische Berechnungen, Lohnberechnungen
description: Darin: Anmerkungen von 1947/50 über Herkunft und Verwendung des Büchleins
description: Deutsch
description: Verzeichnung=Description=Inventaire 02.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
title: Magnetic resonance urography vs computed tomography urography in urothelial malignancy diagnosis
Creators: name: Martingano, Paola
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Urinary Tract / Bladder
subject: MR
subject: CT
subject: Neoplasia

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: To evaluate by a direct comparison the diagnostic accuracy in urothelial malignancy detection of Magnetic Resonance Urography (MRU) and Computed Tomography Urography...
Effectiveness of Incorporating the Think Pair Share Technique Into Cooperative Activity-Based Learning on English-Major Students’ Teamwork Ability
Creators: name: Chayaporn Kaoropthai
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: activity-based learning
cooperative learning
english-major students
teamwork ability
think pair share technique

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 50-63
Interims Inventarium
Creators: name: Lucas Preiswerk
Publisher: name: [s.n.]
Year: 1819

description: Enthält: Inventar gefärbte Seide, Schulden Arbeiterlöhne, fabrizierte Ware
description: Firma Lucas Preiswerk
description: Deutsch
description: Verzeichnung=Description=Inventaire 02.07.2020 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Digitalisierung=Digitization=Numérisation TIFF 01.11.2020
Additional file 2 of Bridging gaps in oral health education in a medical school in the United States: a pilot study
Creators: name: Morel, Mallory Morse
name: Chuang, Elizabeth
name: Laniado, Nadia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. Study Flow Diagram of Participants. Flow diagram of participants’ path through the studyprotocol, highlighting the division of students requiring protocol modificationdue to the COVID-19 pandemic.
Manual, 1871
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1871

description: [Universitätsbibliothek Basel]
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Juli 2019 HAN-Katalogisierungsregeln Minimalaufnahme nach Autopsie
Result of Learning Management for Self-learning Promotion to Develop Science Learning Innovative Media and Technology, and Communication of Pre-Service Science Teachers
Creators: name: Duangjan Kaewkongpan
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: self-learning
Innovation in learning
Information and communication technology
pre-service science teacher

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 64-82
Additional file 1 of Bridging gaps in oral health education in a medical school in the United States: a pilot study
Creators: name: Morel, Mallory Morse
name: Chuang, Elizabeth
name: Laniado, Nadia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Posttest analysis of student comfort andfamiliarity with topics in oral health pre (n=19) and post COVID-19 (n=18). Tableand analysis of responses to survey questions pre and post COVID-19.
Ethical Behaviors among Nursing Students, School of Nursing, Rangsit University
Creators: name: Naphatsakon Vitoonmetha
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: ethical behaviors
nursing students
private university

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 83-101
Manual, 1872
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1872

description: [Universitätsbibliothek Basel]
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Juli 2019 HAN-Katalogisierungsregeln Minimalaufnahme nach Autopsie
Computer-aided analysis for identification of novel analogues of ketoprofen based on molecular docking, ADMET, drug-likeness and DFT studies for the treatment of inflammation
Creators: name: Bettadj, Fatima Zohra Yasmine
name: Benchouk, Wafaa
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Computer-based drug design is increasingly used in strategies for discovering new molecules for therapeutic purposes. The targeted drug is ketoprofen (KTP), which belongs to the family of non-steroidal anti-inflammatory drugs, which are widely used for the treatment of pain, fever, inflammation and certain types of cancers. In an attempt to rationalize the search for 72 new potential anti-inflammatory compounds on the COX-2 enzyme, we carried out an in silico protocol that successfully combines molecular docking towards COX-2 receptor (5F1A), ADMET pharmacokinetic parameters, drug-likeness rules and molecular electrostatic potential (MEP). It was found that six of the compounds analyzed satisfy with the associated values to physico-chemical properties as key evaluation parameters for the drug-likeness and demonstrate a hydrophobic character which makes their solubility in aqueous media difficult and easy in lipids. All the compounds presented good ADMET profile and they showed an interaction with the amino acids responsible for anti-inflammatory activity of the COX-2 isoenzyme. The calculation of the MEP of the six analogues reveals new preferential sites involving the formation of new bonds. Consequently, this result allowed us to understand the origin of the potential increase in the anti-inflammatory activity of the candidates. Finally, it was obtained that six compounds have a binding mode, binding energy, and stability in the active site of COX-2 like the reference drug ketoprofen, suggesting that these compounds could become a powerful candidate in the inhibition of the COX-2 enzyme. Communicated by Ramaswamy H. Sarma
Manual, 1874
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1874

description: [Universitätsbibliothek Basel]
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Juli 2019 HAN-Katalogisierungsregeln Minimalaufnahme nach Autopsie
Manual, 1876
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1876

description: [Universitätsbibliothek Basel]
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Juli 2019 HAN-Katalogisierungsregeln Minimalaufnahme nach Autopsie
title: Comparison of dissatisfaction level after bowel preparation for CT colonography and colonoscopy
Creators: name: Cabral, Pedro
Publisher: name: European Congress of Radiology
Year: 2011
Subjects: subject: Colonography CT
subject: Gastrointestinal tract

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: Colon studies are gaining more widespread acceptance and are already considered a fundamental part of every patient'sscreening evaluation program. For the patients' despair, the bowel preparation schemes are still an enormous obstacle to overcome....
A Development of the Authentic Assessment Model of GPAS Instructional for Primary School Students
Creators: name: Pattanajit Sukpaiboon
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: authentic assessment model
instructional management
GPAS process
primary education

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 102-118
Strengthen Thinking Skills in Teaching and Learning of Volleyball for Students in the Field of Physical Education and Health Education a 5-Year Academic
Creators: name: Manaspoom Sasanasart
Publisher: name: บริษัท เอเชีย ดิจิตอลการพิมพ์ จำกัด
Year: 2022
Subjects: Needs Assessment
Thinking Skills

description: Journal of Rangsit University: Teaching & Learning, 16, 1, 119-137
Nipponaetes hansoni
Creators: name: Khalaim, Andrey I.
name: Kasparyan, Dmitri R.
name: López-Ortega, Maurilio
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Nipponaetes
Nipponaetes hansoni

description: 48. Nipponaetes hansoni (Gauld, 1997)
(Figs 17, 18)
Remarks. The species was described from Costa Rica in the genus Zurquilla Gauld belonging to the tryphonine tribe Oedemopsini (Gauld et at. 1997: 406), but later Zurquilla was transferred to the cryptine tribe Phygadeuontini as a synonym of Nipponaetes Uchida (Broad et al. 2004). According to its original description and illustration (Fig. 439 in Gauld et at. 1997), Z. hansoni lacks sternaulus, but actually sternaulus in this species is present, it is deep and sharp in anterior half of mesopleuron (Fig. 17).
Shape of the ovipositor in N. hansoni is convergently similar to those in oedemopsini genera and differs from ovipositors in typical members of the Nipponaetes (e.g. see Fig. 66 in Townes 1970). Althought N. hansoni undoubtedly belongs to the Cryptinae, its taxonomic status within this subfamily remains unclear and requires further investigation (Kasparyan pers. obs.).
Material examined. Veracruz: 1 ♀ (UAT) SW of Xalapa, park near Institute de Ecología, N 19°30.768′, W 96°56.349′, 1260 m, 17–18.II.2009, coll. A.I. Khalaim; apex of metasoma destroyed and ovipositor lost. Distribution. * Mexico (Veracruz), Costa Rica. First record of genus from Mexico.
description: Published as part of Khalaim, Andrey I., Kasparyan, Dmitri R. & López-Ortega, Maurilio, 2018, New records and descriptions of Ichneumonidae (Hymenoptera) from Mexico, pp. 1-30 in Zootaxa 4486 (1) on pages 15-17, DOI: 10.11646/zootaxa.4486.1.1, http://zenodo.org/record/1437993
Molecular docking and dynamics studies for the identification of Nipah virus glycoprotein inhibitors from Indian medicinal plants
Creators: name: Abhinand, Chandran S.
name: Ibrahim, Junaida
name: Prasad, Thottethodi Subrahmanya Keshava
name: Raju, Rajesh
name: Oommen, Oommen V.
name: Nair, Achuthsankar S.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The infection by Nipah Virus (NiV), a zoonotic paramyxovirus, is fatal and several outbreaks have been reported in humans in various countries. No effective vaccines or drugs are developed till date to control this infection. The NiV-Glycoprotein (NiV-G) is one of the essential proteins for viral entry by binding to the Ephrin-B receptors. The present study screens the potential phytocompounds that can target NiV-G and thereby inhibit the viral entry to human. Computer-aided virtual screening of 1426 phytocompounds from various medicinal plants was carried out to investigate their efficacy as potential therapeutics. Ribavirin, the currently used drug, was also docked to compare the docking score and intermolecular interactions between ligand and target protein. Further, molecular dynamics simulations and MM-PBSA binding free energy calculations were performed to understand the stability of the docked complexes. Radius of gyrations and Solvent Accessible Surface Area were also performed to evaluate the compactness and solvent behaviour of ligand-receptor complexes during the 100 ns simulation. Our analysis revealed that the alkaloid, Serpentinine, has the highest potency to block NiV-G with favourable binding. Communicated by Ramaswamy H. Sarma