cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dynamic Hyper-Graph Inference Framework for Computer-Assisted Diagnosis of Neurodegenerative Diseases
Creators: name: Zhu, Xiaofeng
name: Yan, Jin
name: Zhu, Yingying
name: Wu, Guorong
name: Kim, Minjeong
name: Kaufer, Daniel
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2018

description: Hyper-graph techniques have been widely investigated in computer vision and medical imaging applications, showing superior performance for modeling complex subject-wise relationships and sufficient flexibility to deal with missing data from multi-modal neuroimaging data. Existing hyper-graph methods, however, are inadequate for two reasons. First, representations are generated only from the observed imaging data, a process that is completely independent of the subsequent data label inference/ classification step. Thus, hyper-graph results constructed in this way may not be consistent with phenotype data such as clinical labels or scores. More critically, it might generate sub-optimal predictions in relation to clinical labels/scores. Second, current hyper-graph inference methods rely on two sequential steps: 1) building the hyper-graph for each individual modality and then predicted latent labels for new subjects upon each constructed hyper-graph and 2) a voting procedure to incorporate inference results across different hyper-graphs. This approach, however, is limited by failing to consider the complex and complementary relationships of multi-modal imaging data with respect to hyper-graph inference procedure. To address these two issues, we propose a novel dynamic hyper-graph inference method supported by a semi-supervised framework. Our method iteratively estimates and adjusts the hyper-graph structures from multi-modal imaging data until consistency between the learned hyper-graph and the observed clinical labels and scores is achieved. This hyper-graph inference framework also eases the integration process of classification (identifying individuals having neurodegenerative disease) and regression (predicting the clinical scores) within the same framework. The experimental results on identifying mild cognition impairment (MCI) subjects and the fine grained recognition of MCI progression stages show improved performance using our proposed hyper-graph inference method compared with conventional methods.
sj-pdf-14-hpq-10.1177_13591053231184032 – Supplemental material for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses
Creators: name: Shannonhouse, Laura
name: Lopez, Jorge
name: Hall, M Elizabeth Lewis
name: Silverman, Eric
name: Captari, Laura E
name: Park, Crystal L
name: McMartin, Jason
name: Kapic, Kelly
name: Aten, Jamie
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 170199
subject: Psychology not elsewhere classified
classificationCode: 110319
subject: Psychiatry (incl. Psychotherapy)
classificationCode: 111799
subject: Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-pdf-14-hpq-10.1177_13591053231184032 for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses by Laura Shannonhouse, Jorge Lopez, M Elizabeth Lewis Hall, Eric Silverman, Laura E Captari, Crystal L Park, Jason McMartin, Kelly Kapic and Jamie Aten in Journal of Health Psychology
88311: The Funeral
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Part of a Typescript of 'The Patchwork Flag', which included 38 examples of war and children's verses, with Robert Graves' manuscript corrections. Compiled with Nancy Nicholson. Sent also to Edward Marsh. Contains one two-sided leaf of a manuscript comments by Siegfried Sassoon, dated 21st August (1918)" Not published after Graves received criticism both from Sassoon And Robert Ross.
Identifying disease-related subnetwork connectome biomarkers by sparse hypergraph learning
Creators: name: Wu, Guorong
name: Zhang, Daoqiang
name: Gao, Yue
name: Peng, Ziwen
name: Cohen, Jessica R.
name: Kim, Minjeong
name: Zu, Chen
name: Munsell, Brent
Publisher: name: Springer Nature
Year: 2018

description: The functional brain network has gained increased attention in the neuroscience community because of its ability to reveal the underlying architecture of human brain. In general, majority work of functional network connectivity is built based on the correlations between discrete-time-series signals that link only two different brain regions. However, these simple region-to-region connectivity models do not capture complex connectivity patterns between three or more brain regions that form a connectivity subnetwork, or subnetwork for short. To overcome this current limitation, a hypergraph learning-based method is proposed to identify subnetwork differences between two different cohorts. To achieve our goal, a hypergraph is constructed, where each vertex represents a subject and also a hyperedge encodes a subnetwork with similar functional connectivity patterns between different subjects. Unlike previous learning-based methods, our approach is designed to jointly optimize the weights for all hyperedges such that the learned representation is in consensus with the distribution of phenotype data, i.e. clinical labels. In order to suppress the spurious subnetwork biomarkers, we further enforce a sparsity constraint on the hyperedge weights, where a larger hyperedge weight indicates the subnetwork with the capability of identifying the disorder condition. We apply our hypergraph learning-based method to identify subnetwork biomarkers in Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD). A comprehensive quantitative and qualitative analysis is performed, and the results show that our approach can correctly classify ASD and ADHD subjects from normal controls with 87.65 and 65.08% accuracies, respectively.
Recent Results From Mice On Multiple Coulomb Scattering And Energy Loss
Creators: name: YOUNG, Alan
Publisher: name: Zenodo
Year: 2018

description: Multiple Coulomb scattering and energy loss are well known phenomena experienced by charged particles as they traverse a material. However, from recent measurements by the MuScat collaboration, available simulation codes (GEANT4, for example) are known to overestimate the scattering of muons in low Z materials. This is of particular interest to the Muon Ionization Cooling Experiment (MICE) collaboration which has the goal of measuring the reduction of the emittance of a muon beam induced by energy loss in low Z absorbers. MICE took data without magnetic field suitable for multiple scattering measurements in the fall of 2015 with the absorber vessel filled with xenon and in the spring of 2016 using a lithium hydride absorber. In the fall of 2016 MICE took data with magnetic fields on and measured the energy loss of muons in a lithium hydride absorber. These data are all compared with the Bethe-Bloch formula and with the predictions of various models, including the default GEANT4 model.
Сертифікат про спеціалізоване дистанційне навчання 2024-1196-1007201-273232
Creators: name: Алієва, Тарана Джафар кизи
Publisher: name: Zenodo
Year: 2024

description: Сертифікат про навчання за темою "Ведення поширених розладів на первинному рівні медичної допомоги із використанням керівництва mhGAP" в Академії національної служби здоров'я України підтверджує проходження навчання протягом 30 годин (15 балів БПР).

https://doi.org/10.5281/zenodo.11375038
88315: The Patchwork Flag
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Part of a Typescript of 'The Patchwork Flag', which included 38 examples of war and children's verses, with Robert Graves' manuscript corrections. Compiled with Nancy Nicholson. Sent also to Edward Marsh. Contains one two-sided leaf of a manuscript comments by Siegfried Sassoon, dated 21st August (1918)" Not published after Graves received criticism both from Sassoon And Robert Ross.
sj-pdf-17-hpq-10.1177_13591053231184032 – Supplemental material for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses
Creators: name: Shannonhouse, Laura
name: Lopez, Jorge
name: Hall, M Elizabeth Lewis
name: Silverman, Eric
name: Captari, Laura E
name: Park, Crystal L
name: McMartin, Jason
name: Kapic, Kelly
name: Aten, Jamie
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 170199
subject: Psychology not elsewhere classified
classificationCode: 110319
subject: Psychiatry (incl. Psychotherapy)
classificationCode: 111799
subject: Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-pdf-17-hpq-10.1177_13591053231184032 for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses by Laura Shannonhouse, Jorge Lopez, M Elizabeth Lewis Hall, Eric Silverman, Laura E Captari, Crystal L Park, Jason McMartin, Kelly Kapic and Jamie Aten in Journal of Health Psychology
sj-pdf-2-hpq-10.1177_13591053231184032 – Supplemental material for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses
Creators: name: Shannonhouse, Laura
name: Lopez, Jorge
name: Hall, M Elizabeth Lewis
name: Silverman, Eric
name: Captari, Laura E
name: Park, Crystal L
name: McMartin, Jason
name: Kapic, Kelly
name: Aten, Jamie
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 170199
subject: Psychology not elsewhere classified
classificationCode: 110319
subject: Psychiatry (incl. Psychotherapy)
classificationCode: 111799
subject: Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-pdf-2-hpq-10.1177_13591053231184032 for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses by Laura Shannonhouse, Jorge Lopez, M Elizabeth Lewis Hall, Eric Silverman, Laura E Captari, Crystal L Park, Jason McMartin, Kelly Kapic and Jamie Aten in Journal of Health Psychology
sj-docx-1-psp-10.1177_01461672231179431 – Supplemental material for Masculinity Threats Sequentially Arouse Public Discomfort, Anger, and Positive Attitudes Toward Sexual Violence
Creators: name: Vescio, Theresa K.
name: Schermerhorn, Nathaniel E. C.
name: Lewis, Kathrine A.
name: Yamaguchi-Pedroza, Katsumi
name: Loviscky, Abigail J.
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 170199
subject: Psychology not elsewhere classified

description: Supplemental material, sj-docx-1-psp-10.1177_01461672231179431 for Masculinity Threats Sequentially Arouse Public Discomfort, Anger, and Positive Attitudes Toward Sexual Violence by Theresa K. Vescio, Nathaniel E. C. Schermerhorn, Kathrine A. Lewis, Katsumi Yamaguchi-Pedroza and Abigail J. Loviscky in Personality and Social Psychology Bulletin
sj-pdf-9-hpq-10.1177_13591053231184032 – Supplemental material for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses
Creators: name: Shannonhouse, Laura
name: Lopez, Jorge
name: Hall, M Elizabeth Lewis
name: Silverman, Eric
name: Captari, Laura E
name: Park, Crystal L
name: McMartin, Jason
name: Kapic, Kelly
name: Aten, Jamie
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 170199
subject: Psychology not elsewhere classified
classificationCode: 110319
subject: Psychiatry (incl. Psychotherapy)
classificationCode: 111799
subject: Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-pdf-9-hpq-10.1177_13591053231184032 for “God wastes nothing”: A consensual qualitative study of coping among Catholic individuals with cancer diagnoses by Laura Shannonhouse, Jorge Lopez, M Elizabeth Lewis Hall, Eric Silverman, Laura E Captari, Crystal L Park, Jason McMartin, Kelly Kapic and Jamie Aten in Journal of Health Psychology
VERS UNE AMELIORATION DE LA PERFORMANCE DES PME PAR LA REDUCTION DU RISQUE DANS UN CONTEXTE DE L'INTELLIGENCE ARTIFICIELLE
Creators: name: HELMI, Driss
name: KAYA, Kamel
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Risk Management, Artificial Intelligence, MAS, PDCA.

description: La nature risquée de la conduite de projets est largement reconnue. En effet, aussi importants que soient les gains visés par une organisation lorsqu’elle entreprend un projet, les dépassements de budget ou de délais, l’insatisfaction des clients du projet, le manque de qualité des livrables, la perte de qualité du logiciel, la réduction de la fonctionnalité peuvent diminuer et même parfois anéantir les bénéfices escomptés. Cependant force est de constater que tout se passe comme si dans la recherche sur le processus de production de l’accident, on exclut une phase importante, celle justement de l’analyse et de l’évaluation des risques présente normalement à toutes les phases du système, depuis sa conception jusqu’à son démantèlement ou sa mise au rebut. Comme pour le Système de Management de la Qualité défini par l’ISO 9001, le dispositif de gestion du risque opérationnel a vocation à suivre un cycle continu d’amélioration de type PDCA (Plan, Do, Check, Act). Il s’agit des quatre étapes de l’amélioration continue mentionnées dans la norme ISO 9001 et également s’appuie sur le processus de Management des Risques (ISO 31000). La réduction des risques n’est que l’une des composantes de l’amélioration de la performance, qui vise également à réduire (en moyenne et en variabilité) les délais, les coûts et les défauts. L’objectif d’un processus de gestion des risques opérationnels est d’améliorer les processus, renégocier les assurances et sensibiliser l’entreprise aux risques opérationnels (culture risque). Notre travail consiste à systématiser la culture de risque à travers le recours à des outils de l’Intelligence Artificielle s’appuyant sur l’utilisation des Systèmes Multi-Agents(SMA). Cela permettra sans doute à l’entreprise de : ü Baisser le coût lié aux pertes opérationnelles (en moyenne et surtout en variabilité) de manière à générer un accroissement durable de la rentabilité de l’établissement, ü Réduire la probabilité d’occurrence et la sévérité d’événements extrêmes qui pourraient amputer le résultat, voire les fonds propres. Même si chaque entreprise a son approche personnalisée du sujet, le modèle du management du risque que nous proposons reflète l’essentiel d’un tel dispositif.
description: Revue Economie, Gestion et Société, No 6 (2016)
66072: The Volunteer
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Manuscript in pen in Marion Scott's hand. After a manuscript from a letter of 29th August 1917 to Scott. Also found in the blue exercise book 52.5. The quotation in stanza 5 is from the American poet Walt Whitman's 'Passage to India'. Published in 'The Spectator' on 22nd February 1919. Included in 'War's Embers' (1919).
66073: Turmut-Hoeing
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Manuscript in pen in Marion Scott's hand. Exists in numerous drafts without change. Included in 'War's Embers' (1919).
sj-pdf-1-jva-10.1177_11297298231185793 – Supplemental material for Surgical and endovascular assisted maturation procedures improve cannulation after arteriovenous fistula creation, but not after arteriovenous graft placement
Creators: name: Hafeez, Muhammad Saad
name: Chaer, Rabih A
name: Eslami, Mohammad H
name: Abdul-Malak, Othman M
name: Yuo, Theodore H
Publisher: name: SAGE Journals
Year: 2023
Subjects: Cardiology

description: Supplemental material, sj-pdf-1-jva-10.1177_11297298231185793 for Surgical and endovascular assisted maturation procedures improve cannulation after arteriovenous fistula creation, but not after arteriovenous graft placement by Muhammad Saad Hafeez, Rabih A Chaer, Mohammad H Eslami, Othman M Abdul-Malak and Theodore H Yuo in The Journal of Vascular Access
Additional file 1 of A systematic review on the relationship between the built environment and children’s quality of life
Creators: name: Kodali, Hanish P.
name: Hitch, Lisa
name: Dunlap, Ann F
name: Starvaggi, Marc
name: Wyka, Katarzyna E
name: Huang, Terry TK
Publisher: name: figshare
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Appendix A. Tailored full search strings for databases.
A testing based approach to the discovery of differentially correlated variable sets
Creators: name: Bodwin, Kelly
name: Nobel, Andrew
name: Zhang, Kai
Publisher: name: Institute of Mathematical Statistics
Year: 2018

description: Given data obtained under two sampling conditions, it is often of interest to identify variables that behave differently in one condition than in the other. We introduce a method for differential analysis of second-order behavior called Differential Correlation Mining (DCM). The DCM method identifies differentially correlated sets of variables, with the property that the average pairwise correlation between variables in a set is higher under one sample condition than the other. DCM is based on an iterative search procedure that adaptively updates the size and elements of a candidate variable set. Updates are performed via hypothesis testing of individual variables, based on the asymptotic distribution of their average differential correlation. We investigate the performance of DCM by applying it to simulated data as well as to recent experimental datasets in genomics and brain imaging.
Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors
Creators: name: Zheng, Wei
name: He, Shihua
name: Fisher, Ethan G.
name: Shinn, Paul
name: Zhu, Wenjun
name: Garciiaa-Sastre, Adolfo
name: Capuzzi, Stephen J.
name: Qiu, Xiangguo
name: Tawa, Gregory
name: Sun, Wei
name: Martiianez-Romero, Carles
name: Tropsha, Alexander
name: Muratov, Eugene N.
name: Xu, Miao
name: Li, Hao
Publisher: name: American Chemical Society (ACS)
Year: 2018

description: The Ebola virus (EBOV) causes severe human infection that lacks effective treatment. A recent screen identified a series of compounds that block EBOV-like particle entry into human cells. Using data from this screen, quantitative structure-activity relationship models were built and employed for virtual screening of a ~17 million compound library. Experimental testing of 102 hits yielded 14 compounds with IC50 values under 10 μM, including several sub-micromolar inhibitors, and more than 10-fold selectivity against host cytotoxicity. These confirmed hits include FDA-approved drugs and clinical candidates with non-antiviral indications, as well as compounds with novel scaffolds and no previously known bioactivity. Five selected hits inhibited BSL-4 live-EBOV infection in a dose-dependent manner, including vindesine (0.34 μM). Additional studies of these novel anti-EBOV compounds revealed their mechanisms of action, including the inhibition of NPC1 protein, cathepsin B/L, and lysosomal function. Compounds identified in this study are among the most potent and well-characterized anti-EBOV inhibitors reported to date.
Chemistry-Wide Association Studies (CWAS): A Novel Framework for Identifying and Interpreting Structure-Activity Relationships
Creators: name: Andrade, Carolina Horta
name: Low, Yen S.
name: Rusyn, Ivan
name: Muratov, Eugene N.
name: Alves, Vinicius M.
name: Tropsha, Alexander
name: Fourches, Denis
name: Sedykh, Alexander
Publisher: name: American Chemical Society (ACS)
Year: 2018

description: Quantitative structure-activity relationships (QSAR) models are often seen as a "black box" because they are considered difficult to interpret. Meanwhile, qualitative approaches, e.g., structural alerts (SA) or read-across, provide mechanistic insight, which is preferred for regulatory purposes, but predictive accuracy of such approaches is often low. Herein, we introduce the chemistry-wide association study (CWAS) approach, a novel framework that both addresses such deficiencies and combines advantages of statistical QSAR and alert-based approaches. The CWAS framework consists of the following steps: (i) QSAR model building for an end point of interest, (ii) identification of key chemical features, (iii) determination of communities of such features disproportionately co-occurring more frequently in the active than in the inactive class, and (iv) assembling these communities to form larger (and not necessarily chemically connected) novel structural alerts with high specificity. As a proof-of-concept, we have applied CWAS to model Ames mutagenicity and Stevens-Johnson Syndrome (SJS). For the well-studied Ames mutagenicity data set, we identified 76 important individual fragments and assembled co-occurring fragments into SA both replicative of known as well as representing novel mutagenicity alerts. For the SJS data set, we identified 29 important fragments and assembled co-occurring communities into SA including both known and novel alerts. In summary, we demonstrate that CWAS provides a new framework to interpret predictive QSAR models and derive refined structural alerts for more effective design and safety assessment of drugs and drug candidates.
CONCEPTS DE PARTENARIAT PUBLIC PRIVE ET DE GESTION DELEGUEE: ETUDE COMPARATIVE
Creators: name: EL ANEBRI, Hasna
name: ELOUFIR, Chakib
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Contracts, delegated management, public private partnership, concessions, public service.

description: Le présent article porte sur une étude des concepts des contrats de gestion déléguée et de partenariat public privé d’un point de vue comparatif. Il s’agit de la dimension théorique qui caractérise lesdits contrats, tout en mettant l’accent sur les éléments qui les distinguent et sur ceux qui ont tendance à faire émerger un rapprochement entre certains de leurs éléments constitutifs. La notion de concession est également abordée du fait du lien étroit entre ladite notion et les deux contrats objets de l’étude. Le législateur marocain garde, en effet, le contrat de concession dans certains textes régissant des secteurs spécifiques. La méthodologie adoptée dans le cadre de ce travail est une méthodologie comparative qui confronte les différentes caractéristiques conceptuelles desdits contrats tout en les expliquant.
description: Revue Economie, Gestion et Société, No 6 (2016)
sj-docx-1-sed-10.1177_00224669221113805 – Supplemental material for Influence of Rigid/Ritualistic Behavioral Profiles of Students With Autism Spectrum Disorder on Special Education Teachers’ Perceptions of Their Readiness for Supported Employment
Creators: name: Nah, Yong-Hwee
name: Neo, Hui-Min
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Education
classificationCode: 170199
subject: Psychology not elsewhere classified
classificationCode: 130312
subject: Special Education and Disability

description: Supplemental material, sj-docx-1-sed-10.1177_00224669221113805 for Influence of Rigid/Ritualistic Behavioral Profiles of Students With Autism Spectrum Disorder on Special Education Teachers’ Perceptions of Their Readiness for Supported Employment by Yong-Hwee Nah and Hui-Min Neo in The Journal of Special Education
Identifying Amidyl Radicals for Intermolecular C-H Functionalizations
Creators: name: Alexanian, Erik J.
name: Tierney, Matthew M.
name: Ravelli, Davide
name: Crespi, Stefano
Publisher: name: American Chemical Society (ACS)
Year: 2019

description: Recent studies have demonstrated the capabilities of amidyl radicals to facilitate a range of intermolecular functionalizations of unactivated, aliphatic C-H bonds. Relatively little information is known regarding the important structural and electronic features of amidyl and related radicals that impart efficient reactivity. Herein, we evaluate a diverse range of nitrogen-centered radicals in unactivated, aliphatic C-H chlorinations. These studies establish the salient features of nitrogen-centered radicals critical to these reactions in order to expedite the future development of new site-selective, intermolecular C-H functionalizations.
Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates
Creators: name: Reinhardt, R Lee
name: Samsa, Leigh Ann
name: Lo, Yuan-Hung
name: Magness, Scott T
name: Fordham, Matthew J
name: Raab, Jesse R
name: Bao, Katherine
name: Trotier, Danny C
name: Gracz, Adam D
name: Shroyer, Noah F
name: Zwarycz, Bailey
name: Starmer, Joshua
Publisher: name: Elsevier
Year: 2018

description: BACKGROUND & AIMS: The intestinal epithelium is maintained by intestinal stem cells (ISCs), which produce postmitotic absorptive and secretory epithelial cells. Initial fate specification toward enteroendocrine, goblet, and Paneth cell lineages requires the transcription factor Atoh1, which regulates differentiation of the secretory cell lineage. However, less is known about the origin of tuft cells, which participate in type II immune responses to parasite infections and appear to differentiate independently of Atoh1. We investigated the role of Sox4 in ISC differentiation. METHODS: We performed experiments in mice with intestinal epithelial-specific disruption of Sox4 (Sox4fl/fl:vilCre; SOX4 conditional knockout [cKO]) and mice without disruption of Sox4 (control mice). Crypt- and single-cell-derived organoids were used in assays to measure proliferation and ISC potency. Lineage allocation and gene expression changes were studied by immunofluorescence, real-time quantitative polymerase chain reaction, and RNA-seq analyses. Intestinal organoids were incubated with the type 2 cytokine interleukin 13 and gene expression was analyzed. Mice were infected with the helminth Nippostrongylus brasiliensis and intestinal tissues were collected 7 days later for analysis. Intestinal tissues collected from mice that express green fluorescent protein regulated by the Atoh1 promoter (Atoh1GFP mice) and single-cell RNA-seq analysis were used to identify cells that coexpress Sox4 and Atoh1. We generated SOX4-inducible intestinal organoids derived from Atoh1fl/fl:vilCreER (ATOH1 inducible knockout) mice and assessed differentiation. RESULTS: Sox4cKO mice had impaired ISC function and secretory differentiation, resulting in decreased numbers of tuft and enteroendocrine cells. In control mice, numbers of SOX4+ cells increased significantly after helminth infection, coincident with tuft cell hyperplasia. Sox4 was activated by interleukin 13 in control organoids; SOX4cKO mice had impaired tuft cell hyperplasia and parasite clearance after infection with helminths. In single-cell RNA-seq analysis, Sox4+/Atoh1- cells were enriched for ISC, progenitor, and tuft cell genes; 12.5% of Sox4-expressing cells coexpressed Atoh1 and were enriched for enteroendocrine genes. In organoids, overexpression of Sox4 was sufficient to induce differentiation of tuft and enteroendocrine cells-even in the absence of Atoh1. CONCLUSIONS: We found Sox4 promoted tuft and enteroendocrine cell lineage allocation independently of Atoh1. These results challenge the longstanding model in which Atoh1 is the sole regulator of secretory differentiation in the intestine and are relevant for understanding epithelial responses to parasitic infection.
sj-docx-1-dst-10.1177_19322968231185348 – Supplemental material for Real-World Evidence Analysis of a Hybrid Closed-Loop System
Creators: name: Alwan, Heba
name: Wilinska, Malgorzata E.
name: Ruan, Yue
name: Da Silva, Julien
name: Hovorka, Roman
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 111708
subject: Health and Community Services
classificationCode: 110306
subject: Endocrinology
subject: Medicine
classificationCode: 111199
subject: Nutrition and Dietetics not elsewhere classified

description: Supplemental material, sj-docx-1-dst-10.1177_19322968231185348 for Real-World Evidence Analysis of a Hybrid Closed-Loop System by Heba Alwan, Malgorzata E. Wilinska, Yue Ruan, Julien Da Silva and Roman Hovorka in Journal of Diabetes Science and Technology
Additional file 2 of A systematic review on the relationship between the built environment and children’s quality of life
Creators: name: Kodali, Hanish P.
name: Hitch, Lisa
name: Dunlap, Ann F
name: Starvaggi, Marc
name: Wyka, Katarzyna E
name: Huang, Terry TK
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Supplemental Material Table 1 (S1). Reasons for exclusion during title/abstract screening.
65882: Letter: To Siegfried Sassoon
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: State of Company / a game of squash / discusses the ramifications, political and poetic, of Siegfried Sassoon's declaration against the war, which had just been read out in Parliament.
sj-docx-1-soe-10.1177_00380407231182682 – Supplemental material for Test Participation or Test Performance: Why Do Men Benefit from Test-Based Admission to Higher Education?
Creators: name: Finger, Claudia
name: Solga, Heike
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Education
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-soe-10.1177_00380407231182682 for Test Participation or Test Performance: Why Do Men Benefit from Test-Based Admission to Higher Education? by Claudia Finger and Heike Solga in Sociology of Education
sj-docx-3-pcr-10.1177_26323524231182724 – Supplemental material for Inpatient hospice admissions. Who is admitted and why: a mixed-method prospective study
Creators: name: Haraldsdottir, Erna
name: Lloyd, Anna
name: Bijak, Martyn
name: Milton, Libby
name: Finucane, Anne M.
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 111702
subject: Aged Health Care

description: Supplemental material, sj-docx-3-pcr-10.1177_26323524231182724 for Inpatient hospice admissions. Who is admitted and why: a mixed-method prospective study by Erna Haraldsdottir, Anna Lloyd, Martyn Bijak, Libby Milton and Anne M. Finucane in Palliative Care and Social Practice
Genetic identification of a population of noradrenergic neurons implicated in attenuation of stress-related responses
Creators: name: Chen, Yu-Wei
name: Plummer, Nicholas W.
name: Jones, Grace K.
name: Oyarzabal, Esteban A.
name: Jensen, Patricia
name: Das, Manasmita
name: Shih, Yen-Yu Ian
name: Smith, Kathleen G.
name: Yakel, Jerrel L.
name: Cheng, Qing
name: Malawsky, Daniel
Publisher: name: Springer Nature
Year: 2018

description: Noradrenergic signaling plays a well-established role in promoting the stress response. Here we identify a subpopulation of noradrenergic neurons, defined by developmental expression of Hoxb1, that has a unique role in modulating stress-related behavior. Using an intersectional chemogenetic strategy, in combination with behavioral and physiological analyses, we show that activation of Hoxb1-noradrenergic (Hoxb1-NE) neurons decreases anxiety-like behavior and promotes an active coping strategy in response to acute stressors. In addition, we use cerebral blood volume-weighted functional magnetic resonance imaging to show that chemoactivation of Hoxb1-NE neurons results in reduced activity in stress-related brain regions, including the bed nucleus of the stria terminalis, amygdala, and locus coeruleus. Thus, the actions of Hoxb1-NE neurons are distinct from the well-documented functions of the locus coeruleus in promoting the stress response, demonstrating that the noradrenergic system contains multiple functionally distinct subpopulations.
Additional file 3 of A systematic review on the relationship between the built environment and children’s quality of life
Creators: name: Kodali, Hanish P.
name: Hitch, Lisa
name: Dunlap, Ann F
name: Starvaggi, Marc
name: Wyka, Katarzyna E
name: Huang, Terry TK
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3: Supplemental Material Table 2 (S2). Reasons for exclusion during full-text screening.
Additional file 1 of Comparative accuracy of ChatGPT-4, Microsoft Copilot and Google Gemini in the Italian entrance test for healthcare sciences degrees: a cross-sectional study
Creators: name: Rossettini, Giacomo
name: Rodeghiero, Lia
name: Corradi, Federica
name: Cook, Chad
name: Pillastrini, Paolo
name: Turolla, Andrea
name: Castellini, Greta
name: Chiappinotto, Stefania
name: Gianola, Silvia
name: Palese, Alvisa
Publisher: name: figshare
Year: 2024
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1.
sj-docx-2-psx-10.1177_00323217231185706 – Supplemental material for Building Trust in Political Office: Testing the Efficacy of Political Contact and Authentic Communication
Creators: name: Weinberg, James
Publisher: name: SAGE Journals
Year: 2023
Subjects: classificationCode: 160607
subject: International Relations

description: Supplemental material, sj-docx-2-psx-10.1177_00323217231185706 for Building Trust in Political Office: Testing the Efficacy of Political Contact and Authentic Communication by James Weinberg in Political Studies
Modeling Between-Study Heterogeneity for Improved Replicability in Gene Signature Selection and Clinical Prediction
Creators: name: Yeh, Jen Jen
name: Li, Quefeng
name: Rashid, Naim U.
name: Ibrahim, Joseph G.
Publisher: name: Taylor & Francis
Year: 2019

description: In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent studies have shown that gene signatures are often not replicable. This occurrence has practical implications regarding the generalizability and clinical applicability of such signatures. To improve replicability, we introduce a novel approach to select gene signatures from multiple datasets whose effects are consistently non-zero and account for between-study heterogeneity. We build our model upon some rank-based quantities, facilitating integration over different genomic datasets. A high dimensional penalized Generalized Linear Mixed Model (pGLMM) is used to select gene signatures and address data heterogeneity. We compare our method to some commonly used strategies that select gene signatures ignoring between-study heterogeneity. We provide asymptotic results justifying the performance of our method and demonstrate its advantage in the presence of heterogeneity through thorough simulation studies. Lastly, we motivate our method through a case study subtyping pancreatic cancer patients from four gene expression studies.
Additional file 4 of Comparative accuracy of ChatGPT-4, Microsoft Copilot and Google Gemini in the Italian entrance test for healthcare sciences degrees: a cross-sectional study
Creators: name: Rossettini, Giacomo
name: Rodeghiero, Lia
name: Corradi, Federica
name: Cook, Chad
name: Pillastrini, Paolo
name: Turolla, Andrea
name: Castellini, Greta
name: Chiappinotto, Stefania
name: Gianola, Silvia
name: Palese, Alvisa
Publisher: name: figshare
Year: 2024
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 4.
Additional file 4 of A systematic review on the relationship between the built environment and children’s quality of life
Creators: name: Kodali, Hanish P.
name: Hitch, Lisa
name: Dunlap, Ann F
name: Starvaggi, Marc
name: Wyka, Katarzyna E
name: Huang, Terry TK
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4: Supplemental Material Table 3 (S3). Study-level quality of evidence for included studies.
Development and content validity of a hemodialysis symptom patient-reported outcome measure
Creators: name: Narendra, Julia H.
name: DeWalt, Darren A.
name: Wingard, Rebecca L.
name: Flythe, Jennifer E.
name: Dalrymple, Lorien S.
name: Dorough, Adeline
Publisher: name: Springer Nature
Year: 2018

description: PurposeTo describe the process and preliminary qualitative development of a new symptom-based patient-reported outcome measure (PROM) intended to assess hemodialysis treatment-related physical symptoms.MethodsExperienced interviewers conducted concept elicitation and cognitive debriefing interviews with individuals receiving in-center hemodialysis in the United States. Concept elicitation interviews involved eliciting spontaneous reports of symptom experiences and probing to further explore and confirm concepts. We used patient-reported concepts to generate a preliminary symptom PROM. We conducted 3 rounds of cognitive debriefing interviews to evaluate symptom relevance, item interpretability, and draft item structure. We iteratively refined the measure based on cognitive interview findings.ResultsForty-two adults receiving in-center hemodialysis participated in the concept elicitation interviews. A total of 12 symptoms were reported by >10% of interviewees. We developed a 13-item initial draft instrument for testing in 3 rounds of cognitive interviews with an additional 52 hemodialysis patients. Participant responses and feedback during cognitive interviews led to changes in symptom descriptions, division of the single item "nausea/vomiting" into 2 distinct items, removal of daily activity interference items, addition of instructions, and clarification about the recall period, among other changes.ConclusionsSymptom Monitoring on Renal Replacement Therapy-Hemodialysis (SMaRRT-HD™) is a 14-item PROM intended for use in hemodialysis patents. SMaRRT-HD™ uses a single treatment recall period and a 5-point Likert scale to assess symptom severity. Qualitative interview data provide evidence of its content validity. SMaRRT-HD™ is undergoing additional testing to assess measurement properties and inform measure scoring.
Supplemental Material - Thermal comfort evaluation in architectural studio classrooms – A summer study in a warm to moderate Indian climate
Creators: name: Khambadkone, Naveen K.
name: Madhumati, Prabhukumar
name: Ranganath, Mavukere Nanjundappa
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental Material for Thermal comfort evaluation in architectural studio classrooms – A summer study in a warm to moderate Indian climate by Naveen Kishore Khambadkone, Madhumati P and Ranganath MN in Indoor and Built Environment
sj-pdf-1-jva-10.1177_11297298221139640 – Supplemental material for Risk factors for in-stent restenosis in maintenance hemodialysis patients with central venous occlusive disease and biomechanical assessment of stents
Creators: name: Yu, Yang
name: Xiong, Yuqin
name: Li, Tao
name: Zhou, Jingyuan
name: Yan, Weijie
name: Xiong, Yan
name: Chen, Yu
name: Fu, Ping
Publisher: name: SAGE Journals
Year: 2022
Subjects: Cardiology

description: Supplemental material, sj-pdf-1-jva-10.1177_11297298221139640 for Risk factors for in-stent restenosis in maintenance hemodialysis patients with central venous occlusive disease and biomechanical assessment of stents by Yang Yu, Yuqin Xiong, Tao Li, Jingyuan Zhou, Weijie Yan, Yan Xiong, Yu Chen and Ping Fu in The Journal of Vascular Access
title: Editorial
title: Embracing and Accounting for the Political Economy of Construction
titleType: Subtitle
Creators: name: Rabeneck, Andrew
Publisher: name: Classiques Garnier
Year: 2024
Subjects: subject: Construction
subject: Économie politique
subject: Institutions
subject: Mondialisation
subject: Analyse transversale
subject: Construction
subject: Political economy
subject: Institutions
subject: Globalization
subject: Transverse analysis

description: L'histoire de la construction manque de pratiques formelles, mais elle est de plus en plus répandue en tant que domaine d'étude. À l'heure où les pratiques de construction connaissent des changements spectaculaires à l'échelle mondiale, les historiens de la construction feraient bien d'élargir leur perspective pour refléter l'économie politique au sein de laquelle se situent les objets de leur étude. Une analyse plus transversale refléterait mieux les dynamiques de pouvoir et les forces géopolitiques à l'œuvre dans la construction.
description: Construction history lacks formal practices but is increasingly popular as a field of study. At a time of dramatic global change in construction practice, construction historians might do well to broaden their perspective to reflect the political economy within which the objects of their study are located. More transverse analysis would better reflect the power dynamics and geopolitical forces at work within construction.
60758: Letters from three Goodchild brothers to their mother in Suffolk
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: In total about 300 letters from enlistment to death (December 1915) or the end of active service (July 1916, two surviving brothers). The letters are discussed in "The Goodchilds of Grundisburgh: Four Brothers in the First World War" (privately printed 2008, updated version published online at http://www.goodchilds.org ).

Editor's Comment:

Transcript of letters sent by Pte. 15103 Arthur Goodchild, 9th Bn. Suffolk Regt (date of birth 25 November 1896) to his mother from September 1914 (enlisted) to July 1916 (discharged?).

Transcript of letters sent by Pte. 15176 Edmund Leonard (Ned) Goodchild, "C" Coy. 9th Bn. Suffolk Regt (date of birth 8th September 1893) to his mother from September 1914 (enlisted) to December 1915. Pte. Edmund Goodchild was killed in action 19th December 1915, and is buried in White House Cemetery, St. Jean-Les-Ypres.

Transcript of letters sent by Pte. 12279 George Goodchild, Suffolk Regt (date of birth 25 March 1895) to his mother from August 1914 (enlisted) to July 1916 (transferred to home duty?). Pte. Goodchild was wounded near Loos in November 1915, and was hospitalized in England until February 1916. He later joined the Royal Scots (service no. 52998).
A potential mechanistic role for neuroinflammation in reward processing impairments in autism spectrum disorder
Creators: name: Greene, Rachel K
name: Dichter, Gabriel S
name: Mosner, Maya G
name: Walsh, Erin
Publisher: name: Elsevier
Year: 2018

description: Accumulating evidence suggests that autism spectrum disorder (ASD) may be conceptualized within a framework of reward processing impairments. The Social Motivation Theory of Autism posits that reduced motivation to interact with people and decreased pleasure derived from social interactions may derail typical social development and contribute to the emergence of core social communication deficits in ASD. Neuroinflammation may disrupt the development of mesolimbic dopaminergic systems that are critical for optimal functioning of social reward processing systems. This neuroinflammation-induced disturbance of mesolimbic dopaminergic functioning has been substantiated using maternal immune activation rodent models whose offspring show aberrant dopaminergic corticostriatal function, as well as behavioral characteristics of ASD model systems. Preclinical findings are in turn supported by clinical evidence of increased mesolimbic neuroinflammatory responses in individuals with ASD. This review summarizes evidence for reward processing deficits and neuroinflammatory impairments in ASD and examines how immune inflammatory dysregulation may impair the development of dopaminergic mesolimbic circuitry in ASD. Finally, future research directions examining neuroinflammatory effects on reward processing in ASD are proposed.
sj-docx-1-spp-10.1177_19485506221143593 – Supplemental material for Experience Matters: Civic Discussion Increases Self-Efficacy and Reduces Forecasted Discomfort in Future Conversations
Creators: name: Geiger, Nathaniel
name: Swim, Janet K.
name: Mallett, Robyn K.
name: Mulvey, Laurie L.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-spp-10.1177_19485506221143593 for Experience Matters: Civic Discussion Increases Self-Efficacy and Reduces Forecasted Discomfort in Future Conversations by Nathaniel Geiger, Janet K. Swim, Robyn K. Mallett and Laurie L. Mulvey in Social Psychological and Personality Science