cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Disciplines and Styles in Pure Mathematics, 1800-2000
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: This workshop addressed issues of discipline and style in number theory, algebra, geometry, topology, analysis, and mathematical physics. Most speakers presented case studies, but some offered global surveys of how stylistic shifts informed the transition and transformation of special research fields. Older traditions in established research communities were considered alongside newer trends, including changing views regarding the role of proof.
Impact of adverse event reports from marketing authorization holder-sponsored patient support programs on the performance of signal detection in pharmacovigilance
Creators: name: Lee, Inyoung
name: Lee, Todd A.
name: Crawford, Stephanie Y.
name: Kilpatrick, Ryan D.
name: Calip, Gregory S.
name: Jokinen, Jeremy D.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Marketing authorization holder (MAH)-sponsored patient support programs (PSPs) are a major source of adverse event (AE) reports. The impact of reports from PSPs on the ability to detect AE signals is unclear. We compared signal detection performance using data from PSPs vs. non-PSP sources, and between PSPs providing clinical services vs. PSPs not providing clinical services. Data were obtained from an internal safety database for a global pharmaceutical company 2015–2017. We assessed whether signals were detected for the reference drug-AE pairs using data from PSPs vs. non-PSP sources, and among different PSP services. The performance was evaluated by four measures including area under the receiver operating characteristic curve (AUC) and time-to-signal detection. While the majority of reports were from PSPs, non-PSP sources were better and faster at detecting signals (AUC 0.63 vs. 0.41, p = 0.035; HR 3.52, p = 0.014) compared to PSPs. Within PSPs, PSPs providing clinical services were marginally better at detecting signals (AUC 0.60 vs. 0.41, p = 0.053) but not faster compared to PSPs not providing clinical services. Reports of AEs from PSPs had worse signal detection performance compared to non-PSP sources. Pharmacovigilance experts should be mindful when using databases that contain reports from PSPs for signal detection.
C*-Algebren
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: The theory of C*-algebras plays a major role in many areas of modern mathematics, like Non-commutative Geometry, Dynamical Systems, Harmonic Analysis, and Topology, to name a few. The aim of the conference “C*-algebras” is to bring together experts from all those areas to provide a present day picture and to initiate new cooperations in this fast growing mathematical field.
Freezing and collapse of flexible polymers
Creators: name: Vogel, Thomas
name: Bachmann, Michael
name: Janke, Wolfhard
Publisher: name: arXiv
Year: 2009
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We analyze the freezing and collapse transition of a simple model for flexible polymer chains on simple cubic and face-centered cubic lattices by means of sophisticated chain-growth methods. In contrast to bond-fluctuation polymer models in certain parameter ranges, where these two conformational transitions were found to merge in the thermodynamic limit, we conclude from our results that the two transitions remain well-separated in the limit of infinite chain lengths. The reason for this qualitatively distinct behavior is presumably due to the ultrashort attractive interaction range in the lattice models considered here.
Optimal consumption and investment with bounded downside risk measures for logarithmic utility functions
Creators: name: Kluppelberg, Claudia
name: Pergamenchtchikov, Serguei
Publisher: name: arXiv
Year: 2010
Subjects: subject: Portfolio Management (q-fin.PM)
subject: Probability (math.PR)
subject: Risk Management (q-fin.RM)
subject: FOS: Economics and business
subject: FOS: Mathematics
subject: 91B70, 93E20, 49K30

description: We investigate optimal consumption problems for a Black-Scholes market under uniform restrictions on Value-at-Risk and Expected Shortfall for logarithmic utility functions. We find the solutions in terms of a dynamic strategy in explicit form, which can be compared and interpreted. This paper continues our previous work, where we solved similar problems for power utility functions.
Modeling Financial, Project and Staff Management
Creators: name: Netz, Lukas
name: Gerasimov, Arkadii
name: Michael, Judith
name: Rumpe, Bernhard
name: Letmathe, Peter
Publisher: name: Enterprise Modelling and Information Systems Architectures (EMISAJ)
Year: 2024

description: To obtain more financial freedom, universities and especially their chairs and institutes have to establish a well functioning and reliable financial management and accounting system. Currently, chairs have different technical solutions for these systems, each of which must react individually to external changes and require a high effort to adapt their reports. Thus, they rely on either commercial accounting software, which is not tailored to their specific needs, or standard spreadsheet software making use of complex sheets and cross-references which are error-prone and hard to adapt. We have used domain models and code synthesis methods to create an enterprise information system. This paper shows how models reflect user requirements, evolve with changing requirements and how they impact an agile, model-driven engineering process. The resulting system simplifies the planning of financial management and accounting by university chairs.
description: Enterprise Modelling and Information Systems Architectures (EMISAJ), Vol. 19 (2024)
Wound healing adverse events in kidney transplant recipients receiving everolimus with reduced calcineurin inhibitor exposure or current standard-of-care: insights from the 24-month TRANSFORM study
Creators: name: Citterio, Franco
name: Henry, Mitchell
name: Kim, Dean Y
name: Kim, Myoung Soo
name: Han, Duck-Jong
name: Kenmochi, Takashi
name: Mor, Eytan
name: Tisone, Giuseppe
name: Bernhardt, Peter
name: Gutierrez, Maria Pilar Hernandez
name: Watarai, Yoshihiko
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: In TRANSFORM, de novo kidney transplant recipients received either everolimus in combination with reduced-exposure calcineurin inhibitor (EVR+rCNI) at standard EVR pre-dose concentrations of 3–8 ng/mL or mycophenolic acid plus standard-exposure CNI (MPA+sCNI). The authors analyzed the incidence of wound healing adverse events (WHAEs) over the 2-year study period 15. Patients were randomized to either EVR+rCNI or MPA+sCNI, both combined with induction therapy and steroids 19. The safety population consisted of 2,026 patients (EVR+rCNI: 1,014, MPA+sCNI: 1,012). The proportion of patients with at least 1 WHAE was comparable between EVR+rCNI and MPA+sCNI treatment groups [20.6% vs. 17.3%; risk ratio (RR): 1.19; 95% confidence interval (CI): 0.99, 1.43] at month 24. The numerical difference between EVR+rCNI and MPA+sCNI was mainly caused by an increased proportion of EVR patients with lymphocele and wound dehiscence [7.5% vs. 5.1% (RR: 1.46; 95% CI: 1.04, 2.05) and 3.9% vs. 1.8% (RR: 2.22; 95%CI: 1.28, 3.84), respectively] 20. The immediate introduction of EVR+rCNI after kidney transplantation was associated with an overall comparable incidence of WHAEs versus current standard-of-care over the 24-month study period. There was an increased relative risk of experiencing lymphocele and wound dehiscence but the absolute risks were rather low in both groups 21. NCT01950819.
Microstructures in Solids: From Quantum Models to Continua
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: The mathematical theory of solids was studied from the modern perspective of materials with microcstructures. The discussed topics ranged from experimental findings, via numerical simulations and mathematical modeling to the analysis of models with microstructures. A special emphasis was given to theories providing rigorous insight into and justification of the limit passage between different scales.
egfl6 expression in the pharyngeal pouch is dispensable for craniofacial development
Creators: name: Jin, Sil
name: Na, Hyejee
name: Jeon, Haewon
name: Park, Jangwon
name: Choe, Chong Pyo
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Epidermal growth factor-like domain multiple 6 (Egfl6) is a basement membrane protein and plays an important role in hair follicle morphogenesis, angiogenesis, notochord development in vertebrates. Although egfl6 expression in the developing head was observed in zebrafish, its role for craniofacial development and the determination of the pharyngeal region expressing egfl6, have not been reported yet. Here, we report the expression patterns and function of egfl6 in craniofacial development in zebrafish. egfl6 was expressed sequentially in the developing pharyngeal pouches that are key epithelial structures governing the development of the vertebrate head. However, loss-of-function mutations in egfl6 did not cause any craniofacial defects, including the pouches as well as the thymus and facial cartilages whose development is contingent upon appropriate pouch formation. egfl6 was unlikely redundant with egfl7 expressed in a distinct pharyngeal region from that of egfl6 in craniofacial development because reduction of egfl7 with a MO in egfl6 mutants did not affect craniofacial development. In addition, we found that egfl6 carried an endogenous start loss mutation in the wild-type Tübingen strain, implying egfl6 would be a non-functional gene. Taken all together, we suggest that egfl6 expression in the pharyngeal pouches is not required for craniofacial development in zebrafish.
Safety evaluation of immune-based combinations in patients with advanced renal cell carcinoma: a systematic review and meta-analysis
Creators: name: Massari, Francesco
name: Mollica, Veronica
name: Rizzo, Alessandro
name: Cosmai, Laura
name: Rizzo, Mimma
name: Porta, Camillo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Immune-based combinations, including nivolumab plus ipilimumab, pembrolizumab plus axitinib, and (at a lesser extent) avelumab plus axitinib, should be regarded among the new standards of care for first line therapy of metastatic renal cell carcinoma. Toxicity profiles are different among all these above combinations, as well as between them and targeted agents monotherapies, including sunitinib (i.e. the control arm of all the above studies). We performed a systematic review and meta-analysis with the aim to compare adverse events from immune-based combinations versus sunitinib monotherapy across four recent randomized controlled trials (CheckMate-214, Keynote-426, IMmotion-151, and JAVELIN Renal 101) of front-line treatment for metastatic renal cell carcinoma, with particular attention to those from the ipilimumab plus nivolumab combination. Beyond efficacy and activity, the ipilimumab plus nivolumab combination appears feasible, being endowed by an acceptable safety profile, in line with that of the other available options for the treatment of metastatic RCC. The different patterns of toxicities emerging from this systematic review and meta-analysis need to be kept in mind while choosing the appropriate treatment for each individual patient. Furthermore, prevention, prompt identification, and treatment of immune-related adverse events remains an area to be improved.
Additional file 1 of Multisystem ALK-positive histiocytosis: a multi-case study and literature review
Creators: name: Liu, Wei
name: Liu, Hong-jie
name: Wang, Wei-ya
name: Tang, Yuan
name: Zhao, Sha
name: Zhang, Wen-yan
name: Yan, Jia-qi
name: Liu, Wei-ping
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Fig. S1. Clinicopathologic features of ALK-positive histiocytosis. A, Case 1-the fiber bronchoscopy biopsy exhibited large histiocytes with frequent Touton giant cells similar to the mediastinal lesion. B, Case 1-the tumor cells were positive for CD163 (mediastinal lesion). C, Case 3-The lesions involved the entire thickness of the gallbladder wall. D, Case 3-the liver lesions were nodular and poorly demarcated. E, Case 3-the histiocytes were positive for CD163 (skin). F, Case 4-a yellowish papula could be seen on the skin of the chest wall. (Original magnification ×40 [C,D]; ×200 [A,B,E]). Fig. S2. Molecular features of ALK-positive histiocytosis. A, Case 1- EML4-ALK gene fusion with breakpoints at EML4 exon 19 and ALK exon 20. B, Case 2 -KIF5B-ALK gene fusion with breakpoints at KIF5B exon 24 and ALK exon 20. C, Case 3 - VRK2-ALK gene fusion with breakpoints at VRK2 exon 11 and ALK exon 20. D, Case 3 -DCTN1-ALK gene fusion with breakpoints involving DCTN1 exon 26 and ALK exon 20. E, Case 4 -KIF5B-ALK gene fusion with breakpoints at KIF5B exon 24 and ALK exon 20.
Two-Flavor Chiral Perturbation Theory for Hyperons
Creators: name: Tiburzi, B. C.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The three-flavor chiral expansion for octet baryons has well-known problems with convergence. We show that this three-flavor chiral expansion can be reorganized into a two-flavor expansion thereby eliminating large kaon and eta loop contributions. Issues of the underlying formulation are addressed by considering the effect of strangeness changing thresholds on hyperon masses. While the spin-3/2 hyperon resonances are considerably more sensitive to these thresholds compared to the spin-1/2 hyperons, we demonstrate that in both cases the essential physics can be captured in the two-flavor effective theory by terms that are analytic in the pion mass squared, but non-analytic in the strange quark mass. Using the two-flavor theory of hyperons, baryon masses and axial charges are investigated. Loop contributions in the two-flavor theory appear to be perturbatively under control. A natural application for our development is to study the pion mass dependence of lattice QCD data on hyperon properties.
description: 9 pages, 3 figures, talk given at 6th International Workshop on Chiral Dynamics, July 6-10, 2009, Bern Switzerland
Combinatorial Representation Theory
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: The workshop brought together researchers from different fields in representation theory and algebraic combinatorics for a fruitful interaction. New results, methods and developments ranging from classical and modular representation theory, the theory of symmetric functions and Lie theory to cluster algebras and connections to physics and geometry were discussed.
Modern Nonparametric Statistics: Going Beyond Asymptotic Minimax
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: During the years 1975-1990 a major emphasis in nonparametric estimation was put on computing the asymptotic minimax risk for many classes of functions. Modern statistical practice indicates some serious limitations of the asymptotic minimax approach and calls for some new ideas and methods which can cope with the numerous challenges brought to statisticians by modern sets of data.
Genetic diversity and virulence variability in Diplodia mutila isolates from symptomatic grapevines in New Zealand
Creators: name: Baskarathevan, Jeyaseelan
name: Jones, E. Eirian
name: Jaspers, Marlene V.
name: Ridgway, Hayley J.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2023

description: Genetic diversity and virulence variability of Diplodia mutila isolates recovered from grapevines in New Zealand were investigated. The universally primed PCR (UP-PCR) and vegetative compatibility group (VCG) methods were used to investigate the genetic diversity. Pathogenicity tests with ‘Sauvignon Blanc’ detached shoots and potted vines were used to determine the virulence diversity. UP-PCR analysis determined eight genetic groups of D. mutila with 70% of the population within one group. Phylogenetic analysis also determined that New Zealand isolates were more closely related to Australian isolates than Californian isolates. Vegetative compatibility grouping analysis placed the isolates into three VCG groups, with 57% of isolates belonging to all three VCGs. Vegetative compatibility reactions were observed among isolates, but this was not correlated with the genetic clustering. Virulence assays proved that all isolates tested were pathogenic on grapevine stems. Differences in necrotic lesions lengths caused by D. mutila isolates were identified, indicating different virulence levels among isolates, however, no relationship was found between the genetic groups and the virulence. The results of the study indicated movement of D. mutila isolates between nurseries, vineyards, and other sources in New Zealand. This information will inform control strategies to limit the further spread of this pathogen into vineyards in the same region or new regions.
description: VITIS - Journal of Grapevine Research, Vol. 62 No. 2 (2023): Vitis
Arbeitsgemeinschaft: Mathematical Billards
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: The workshop Mathematical Billiards, organised by Serge Tabachnikov (Penn State) and Serge Troubetzkoy (Marseille) was held April 4th–April 10th, 2010. This meeting was well attended by over 40 participants including a number of master and PhD students, with broad geographic representation. This workshop was a nice blend of researchers with various backgrounds who brought in their various point of views to cover the classics as well as recent advances in mathematical billiards and flat surfaces. The report consists in the abstracts for the 18 lectures, followed by the abstracts for the 4 short talks that took place in the evenings. During the workshop, there was also a demo of the mathematical software Sage.
Aharonov-Bohm effect in undoped graphene: Magnetotransport via evanescent waves
Creators: name: Katsnelson, M. I.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Using conformal mapping technique, compact and general analytic expressions for the effects of magnetic fluxes on conductance and Fano factor of undoped graphene nanoflakes in pseudodiffusive regime are derived.
description: 3 pages
Image recognition applied to the hoard of Le Câtillon II
Creators: name: Deligio, Chrisowalandis
name: Tolle, Karsten
name: De Jersey, Philip
Publisher: name: Zenodo
Year: 2023
Subjects: celtic coinage
unsupervised image classification
INC
celtic numismatics

description: The presentation deals with the methods and results applied to the hoard of Le Câtillon II in the project Classifications and Representations for Networks: From types and characteristics to linked open data for Celtic coinages, funded by the German Federal Ministry of Education and Research (BMBF). The dataset was provided by Jersey Heritage.
Prokinetic effects of diatrizoate meglumine (Gastrografin®) in a zebrafish for opioid-induced constipation model
Creators: name: Kim, Dongwoo
name: Koun, Soonil
name: Kim, Seung Young
name: Ha, Young Ran
name: Choe, Jung Wan
name: Jung, Sung Woo
name: Hyun, Jong Jin
name: Jung, Young Kul
name: Koo, Ja Seol
name: Yim, Hyung Joon
name: Lee, Sang Woo
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Constipation is a common disease that reduces life quality. Drugs of various mechanisms are being developed to resolve this affliction. Intestinal motility can be easily monitored in zebrafish, and so we selected this organism to develop a constipation model to measure drug-induced prokinetic effects. In this study, intestinal motility was monitored in zebrafish by tracking intestinal transit using fluorescence, after which an opioid-induced constipation model was established using loperamide. We then evaluated the prokinetic effect of diatrizoate meglumine (Gastrografin®), which has been empirically used to treat post-operative ileus or adhesive small bowel obstructions. Diatrizoate meglumine was effective in promoting bowel movements in an opioid-induced zebrafish constipation model and its prokinetic effect was associated with an increased expression of interstitial cells of Cajal (ICC) markers. Therefore, the loperamide-induced zebrafish constipation model developed herein is a promising tool to evaluate novel constipation therapies.
Assessment of suspected adverse drug reactions in elderly patients with diabetes mellitus based on a Portuguese spontaneous reporting database: analysis of reporting from 2008 to 2018
Creators: name: Monteiro, Cristina
name: Silvestre, Samuel
name: Duarte, Ana Paula
name: Alves, Gilberto
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Age is one of the most important risk factors in the development of diabetes mellitus and certain drug classes indicated for this condition may be associated with clinically important adverse drug reactions (ADRs). The aim of this study was to analyze the suspected ADRs in older patients with diabetes mellitus, reported to the Portuguese Pharmacovigilance System from 2008 to 2018. A retrospective analysis of suspected ADRs reports was performed, involving patients aged ≥65 years. Of a total of 751 reports collected, 439 were considered serious, 199 led to hospitalization and in 19 of them occurred a fatal outcome. Most of them were observed in females (n = 393) and involved patients belonging mainly to the age group 65–74 years (n = 405). Taking into account a total of 2134 suspected ADRs, the most frequent were hypoglycemia (2.67%) and lactic acidosis (2.62%). The drugs specifically indicated for glycemic control were the most frequently involved in ADRs. Most of the ADRs were reported as serious and were mainly associated to drugs in diabetes mellitus. In addition, the majority of them, such as hypoglycemia, are preventable, highlighting the importance to identify possible factors that determine this occurrence, especially in the elderly.
Granger causality for circular variables
Creators: name: Angelini, Leonardo
name: Pellicoro, Mario
name: Stramaglia, Sebastiano
Publisher: name: arXiv
Year: 2009
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: In this letter we discuss use of Granger causality to the analyze systems of coupled circular variables, by modifying a recently proposed method for multivariate analysis of causality. We show the application of the proposed approach on several Kuramoto systems, in particular one living on networks built by preferential attachment and a model for the transition from deeply to lightly anaesthetized states. Granger causalities describe the flow of information among variables.
description: 4 pages, 5 figures
POWERING THROUGH CHALLENGES: THE ENERGY CRISIS AND ITS IMPACT ON MSMES IN KADUNA METROPOLIS, KADUNA STATE NIGERIA (2015–2022)
Creators: name: Auwalu, Musa
name: Nurudeen, Bashar Saleh
name: Mohammed, Sadiq Garba
Publisher: name: top journals
Year: 2025
Subjects: Energy Crisis, MSMEs, Oil Scarcity, Energy security

description: The global energy crisis, driven by natural and manmade factors, has profound implications for socio-economic development. Notable historical instances, such as the 1973 Oil Crisis triggered by the OPEC embargo, and more recent events like the Russia-Ukraine war, highlight the fragility of energy supply systems. These crises have disrupted global oil and gas supplies, causing severe consequences for enterprises, particularly Micro, Small, and Medium Enterprises (MSMEs), which are vital to local economies. This study investigates the impact of the energy crisis on MSMEs in Kaduna, Nigeria, during the pre-subsidy removal era (2015–2022), focusing on how fuel scarcity and rising energy costs hinder their operations and profitability. Anchored in the Resource-Based Theory (RBT), the study explores how energy, as a critical resource, affects MSME performance and sustainability. An interpretivist methodology that employs qualitative approaches, incorporating both primary and secondary data, alongside content analysis. The findings reveal that energy crises, exacerbated by global disruptions and domestic inefficiencies, significantly hinder MSME operations in Kaduna. Key effects include increased costs of goods and services, reduced profitability, and the collapse of several enterprises. The study further highlights how fuel scarcity and high energy costs directly undermine socio-economic development in Kaduna and Nigeria at large. The research concludes that addressing energy crises requires immediate and strategic interventions. Recommendations include establishing a multi-sectoral taskforce to monitor petroleum product distribution, reviving and scaling up refinery operations, issuing modular refinery licenses, and increasing investment in renewable energy. Additionally, tailored support such as toolkits for MSMEs can help mitigate the adverse impacts of energy crises. This study contributes to knowledge by providing a nuanced understanding of the interplay between energy crises and MSME performance, offering practical solutions for policymakers and stakeholders to foster resilience and sustainable development.
Purple corn extract alleviates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like phenotypes in BALB/c mice
Creators: name: No, Huiwon
name: Nam, Sang Hyun
name: Seo, Hee Won
name: Seo, JeongHyeon
name: Park, Soo-Hyun
name: Kim, Set-Byeol
name: Jung, Jun-Sub
name: Park, Jongyeol
name: Choi, Jaekeun
name: Lee, Jae-Yong
name: Suh, Hong-Won
name: Lim, Soon Sung
name: Kim, Jin-Kyung
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Zea mays L. (Poaceae), also known as purple corn, is an annual herbaceous plant that is grown as food for human consumption in a variety of forms, including cooking oils and sweeteners in processed food and beverage products. The purpose of this study was to determine whether a novel purple corn extract, FB801, might have an anti-atopic dermatitis (AD) effect on AD-like skin lesions induced by 2,4-dinitrochlorobenzene (DNCB) in BALB/c mice. Topical sensitization (1%) and challenge (0.3%) by DNCB were performed on the dorsal skin and right ear of BALB/c mice to induce AD. Following FB801 and dexamethasone administered orally, the severity of skin lesions was examined macroscopically and histologically. Serum levels of immunoglobulin E (IgE) and various cytokines were determined by enzyme-linked immunosorbent assay. Oral administration of FB801 significantly reduced typical symptoms of AD (erythema/bleeding, swelling, molting/erosion and scaling/drying), scratching frequencies, and the recruitment of inflammatory and mast cells. In addition, FB801 suppressed serum levels of IgE and T helper (Th)2 type cytokines such as interleukin (IL)-4 and IL-10 in DNCB-treated BALB/c mice. Furthermore, FB801 reduced the degradation of inhibitor of nuclear factor-κB proteins (NF-κB) in tumor necrosis factor (TNF)-α-stimulated human keratinocyte (HaCaT) cells. These results suggest that FB801 inhibited the development of the AD-like skin symptoms by regulating Th1 and Th2 responses in the skin lesions in mice and suppressing TNF-α induced NF-κB activation in HaCaT cells, suggesting that FB801 has potential application as an effective alternative therapy for the prevention and management of AD.
Mathematics and Algorithms in Tomography
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: This is the eighth Oberwolfach conference on the mathematics of tomography. Modalities represented at the workshop included X-ray tomography, sonar, radar, seismic imaging, ultrasound, electron microscopy, impedance imaging, photoacoustic tomography, elastography, vector tomography, and texture analysis.
An Extended Concept of Delegation and its Implementation within a Modelling and Programming Language Architecture
Creators: name: Frank, Ulrich
name: Clark, Tony
name: Gulden, Jens
name: Töpel, Daniel
Publisher: name: Enterprise Modelling and Information Systems Architectures (EMISAJ)
Year: 2024

description: Object-oriented modeling languages provide various concepts to express abstractions, which foster reuse and integrity. Among these concepts, generalization/specialization is of specific relevance. However, in many cases where generalization/specialization seems to be a natural choice, its use is likely to jeopardize a system’s integrity. Delegation has for long been known as an alternative that allows preventing the accidental damage caused by the inproper use of specialization. Nevertheless, delegation is ignored by most tools for object-oriented modeling as well as by many textbooks, which may be caused by the fact that there is no unified conception of delegation, and that delegation is not supported by most object-oriented programming languages. This paper aims at a revival of delegation. To that end, the need for delegation is motivated by the analysis of counter-intuitive effects of specialization. Based on an extensive requirements analysis, a new, extended conception of delegation is presented. It allows for using delegation between classes on any (meta-) level and introduces the "delegation to class" pattern. Delegation in multi-level environments enables an additional reduction of redundancy and, hence, promotes integrity. The paper also presents design guidelines to foster the appropriate use of delegation. With respect to the implementation of delegation with object-oriented programming languages, two alternative flavours of delegation are analyzed. Finally, a prototypical implementation within a language engineering and execution environment does not only demonstrate the use of delegation in a modeling tool, but also its seamless implementation, by featuring a common representation of models and code at runtime.
description: Enterprise Modelling and Information Systems Architectures (EMISAJ), Vol. 19 (2024)
Avaliação nacional digital continuada da efetividade das vacinas anti-COVID no Brasil. VigiVac
Creators: name: Barral-Netto, M
Publisher: name: Zenodo
Year: 2023
Subjects: vaccination
COVID-19
vaccine effectiveness

description: A pesquisa irá analisar dados não-identificados de sistemas de informação em saúde referentes a vacinação e adoecimento por Covid-19, em desenho retrospectivo, visando avaliar a efetividade da vacinação para Covid-19 e ocorrência de efeitos adversos por meio dos desfechos de infecção, internação hospitalar, admissão em UTI e óbito
On the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods
Creators: name: Lee, Anthony
name: Yau, Christopher
name: Giles, Michael B.
name: Doucet, Arnaud
name: Holmes, Christopher C.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Computation (stat.CO)
subject: FOS: Computer and information sciences

description: We present a case-study on the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods. Graphics cards, containing multiple Graphics Processing Units (GPUs), are self-contained parallel computational devices that can be housed in conventional desktop and laptop computers. For certain classes of Monte Carlo algorithms they offer massively parallel simulation, with the added advantage over conventional distributed multi-core processors that they are cheap, easily accessible, easy to maintain, easy to code, dedicated local devices with low power consumption. On a canonical set of stochastic simulation examples including population-based Markov chain Monte Carlo methods and Sequential Monte Carlo methods, we find speedups from 35 to 500 fold over conventional single-threaded computer code. Our findings suggest that GPUs have the potential to facilitate the growth of statistical modelling into complex data rich domains through the availability of cheap and accessible many-core computation. We believe the speedup we observe should motivate wider use of parallelizable simulation methods and greater methodological attention to their design.
description: Expansion of details; a condensed version has been submitted for publication
A study of variability in certain Douglas-fir populations in British Columbia.
Creators: name: Tusko, Frank Ferenc
Publisher: name: University of British Columbia
Year: 2011

description: The present study deals with an extensive morphological survey of variations in Douglas-fir (Pseudotsuga menziesii (Poir.) Franco) in a cross section of its northern distribution from the Pacific Coast eastward to the Rocky Mountains. Objective was to determine whether the morphological variations were significant, and hence applicable to problems of taxonomy and ecology of Douglas-fir. Mass-collections were taken from 854 individual trees from 43 sample areas across British Columbia. The following characteristics were investigated: degree of 'bract spreading'; colour of needles and ovulate strobili; cone length and diameter; cone scale angle; number of cone scales; cone specific gravity; bract and scale length; winged seed dimensions; needle length and thickness, and some of the gross characteristics of trees such as age, height, diameter, site class, crown density, degree of branch spreading, and amount of cone production. Field investigations were supplemented by seed-fall studies and by certain nursery and greenhouse investigations (shade-light treatments, seedling comparisons). Statistical analyses employing several procedures (t-test, F-test, Chi-square test, Duncan's test, correlation and multiple regression analyses) established the basis for discussions of the differences between coastal and interior populations of Douglas-fir, as well as geographical distribution of characters and their variability within the two geographical regions and the localities sampled. Statistical parameters of several morphological characteristics have been determined, as well as their correlations with climatic and site factors. Certain observations and considerations have also been made on the taxonomy and nomenclature of Dougla fir. The following conclusions are reached: Two subspecies of Douglas-fir can be recognized, viz. 1) P. menziesii (Mirb.) Franco ssp. menziesii. Coastal Douglas-fir; and 2) P. menziesii (Mirb.) Franco ssp. glaucescens (Bailly) Schwerin, Interior or Rocky Mountain Douglas-fir. An identification key for the two subspecies and a list of synonyms are also provided.
Algebraic Groups
Creators: name: (:Unkn) Unknown
Publisher: name: Zürich : EMS Publ. House
Year: 2010
Subjects: subject: Konferenzschrift
subject: 510

description: The workshop dealt with a broad range of topics from the structure theory and the representation theory of algebraic groups (in the widest sense). There was emphasis on the following areas: • classical and quantum cohomology of homogeneous varieties, • representation theory and its connections to orbits and flag varieties.
MEASUREMENTS IN THE GRAN SASSO LABORATORY: EVIDENCE FOR NUCLEAR EFFECTS IN ELECTROLYSIS WITH Pd/Ti AND IN DIFFERENT TESTS WITH DEUTERATED HIGH TEMPERATURE SUPERCONDUCTORS
Creators: name: F. CELANI
name: A. SPALLONE
name: L. LIBERATORI
name: B. STELLA
name: F. FERRAROTTO
name: M. CORRADI
name: P. MARINI
name: S. FORTUNATI
name: M. TULUI
Publisher: name: INFN Open Access Repository
Year: 1991

description: Several experiments were performed at the INFN Underground Gran Sasso Laboratory (Italy) in order to detect nuclear signals, if any, coming from deuterated materials in the framework of so called 'Cold Fusion'.  We followed three, quite different, lines of experimental researches. In the first set of experiments we used electrolytic solutions of heavy water and 0.1 M LiOH with some addition of gasseous CO_2, using as cathode a rod of pure Pd or Ti alloys and as anode a Pt net. We detected several intense bursts of gamma rays, lusting up to 15 minutes of duration time, with energy less than 300 KeV. In the second set of experiments we used pellets of sintered High Temperature Superconductors  (HTSC) that underwent deuteration by high pressure (∼ 30 Bar) and temperature (∼ 370K) gas loading procedure. The deuterated samples were several times cycled down to liquid nitrogen temperature and we detected by two indipendent ^3He moderated neutron detectors (1.2% total efficiency), sporadic emission of signals mainly during these thermal cycles. Later on similar tests were performed independently by S.E. Jones and collaborators (provo Univ., Utah) in a deep underground mine and a very intense and short neutron burst was detected by 16 independent ^3He moderated neutron detectors (32% efficiency). In the third set of experiments some additional tests were performed using a low activity Am-Be neutron source, in order to study possible phenomena of enhanced neutron emission by radiation stimulation in these HTSC deuterated compounds. We detected excess counts of 2 statistic standard deviations, pointing to increased D-D cross section due to the effect of ceramic lattice.
Master Thesis Fall 2020.pdf
Creators: name: Gultvedt, Mats
name: Senneset, Kristian
Publisher: name: figshare
Year: 2021
Subjects: Economics

description: In this thesis we seek to examine how modern forecasting approaches can improve estimationsof stock pair correlations, and derived from this, contribute to making portfolios more stable.Volatility of financial markets have experienced increases due to the ongoing global pandemic.This amplifies the issues that investors face when assessing the risk related to theirinvestments. We construct a hybrid model consisting of an ARIMA component to explain thelinear tendencies of correlation, and a Long Short-Term Memory component to explain thenon-linear tendencies. Our approach is populated by data from constituents of Oslo StockExchange ranging a time span from 2006 through the third quarter of 2020. Our results indicatethat modern approaches to forecasting accrue stronger predictive performances than theconventional methods. Across all test periods our proposed hybrid model achieves an RMSEof 0.186 compared to an average benchmark RMSE of 0.237. However, the implications ofthese findings are ambiguous as the increase in predictive performance cannot be said todefinitively outweigh the increase in cost of implementation. Our thesis contributes to theexisting literature by exhibiting the untapped potential of how modern approaches toforecasting can improve accuracy of quantitative inputs for decision making.
Beyond the Screen: The Importance of Human Intelligence (HUMINT) in the Digital Age
Creators: name: Hedgepath, Tyler
Publisher: name: University of Chicago
Year: 2023
Subjects: subject: Intelligence
subject: Espionage
subject: Human Intelligence
subject: HUMINT
subject: Central Intelligence Agency
subject: Mossad
subject: KGB
subject: Signals Intelligence
subject: Artificial Intelligence
subject: SIGINT
subject: AI

description: The proliferation of information technology around the globe has increased the ability of intelligence services to gather information through technical collection methods; this, along with the advent of artificial intelligence being used to supplement these technically inclined methods, calls into question the role that human intelligence (HUMINT) will play in the future. Using case studies of previous intelligence operations, we focus on the flexibility and adaptability of HUMINT, as well as areas where hybrid intelligence methods were utilized for the best results. Finally, we make the case that if we follow artificial intelligence to its inevitable conclusion, we will see HUMINT become more important as AI becomes more powerful and widespread between competing powers and their allies.
OAW 2021 | ORCID - meine persönliche ID in der Wissenschaft
Creators: name: Boxhammer, Tim
Publisher: name: Zenodo
Year: 2021
Subjects: ORCID
open researcher and contributor iD
PID
persistent
Identifikator
Autorenidentifikation
Wissenschaftler:in
Wissenschaft
wissenschaftliches Publizieren

description: Open-Access-Woche 2021 | SUB Hamburg Vortrag mit live Präsentation eines ORCID Profils
 26.10.2021 | 10:00 – 10:30 Uhr Anlässlich der Open-Access-Woche 2021 vermittelt Dr. Tim Boxhammer, Naturwissenschaftler und Mitarbeiter der SUB Hamburg, anhand seines ORCID-Profils, welche Mehrwerte sich als Wissenschaftler:in aus der dauerhaften und eindeutigen Verknüpfung von Forschungsergebnissen mit der persönlichen ORCID iD ergeben. Im Fokus stehen dabei auch die Möglichkeiten der Profilgestaltung und Vernetzung.
CAN ONE TEST QUANTUM MECHANICS AT THE F-FACTORY?
Creators: name: G. GHIRARDI
name: R. GRASSI
name: R. RAGAZZON
Publisher: name: INFN Open Access Repository
Year: 1992

description: The problem of the possibility of testing Bell's type inequalities in Φ -> K-K ̅ is discussed. A comparison with EPR-Bohm type experiments for the singlet state and with Aspect's experiments with optical photons is made. We show that, due to the specific features of the two mesons system, no violation of Bell's type inequalities is implied by quantum mechanics. Finally, the deviations from quantum predictions which are implied by the assumption of 'spontaneous factorization' are analyzed.
Supplementary information for: Effects of environmental translocation and host characteristics on skin microbiomes of sun-basking fish
Creators: name: Berggren, Hanna
name: Nordahl, Oscar
name: Yıldırım, Yeşerin
name: Larsson, Per
name: Tibblin, Petter
name: Forsman, Anders
Publisher: name: The Royal Society
Year: 2023
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified
classificationCode: 310799
subject: Microbiology not elsewhere classified
classificationCode: 310901
subject: Animal behaviour

description: Methods on literature survey, DNA extraction, library preparation for 16S sequencing, and sequence processing. Figures S1-4 and Table S1-2.
Threshold Resummation of the Structure Function F_L
Creators: name: Moch, S.
name: Vogt, A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The behaviour of the quark coefficient function for the longitudinal structure function F_L in deep-inelastic scattering is investigated for large values of the Bjorken variable x. We combine a highly plausible conjecture on the large-x limit of the physical evolution kernel for this quantity with our explicit three-loop results to derive the coefficients of the three leading large-x logarithms, alpha_s^n ln^(2n-1-k) (1-x), k = 1, 2, 3, to all orders in the strong coupling constant alpha_s. Corresponding results are derived for the non-C_F part of the gluon coefficient function suppressed by a factor 1-x, and for the analogous subleading (1-x) ln^k (1-x) contributions in the quark case. Our results appear to indicate an obstacle for an exponentiation with a higher logarithmic accuracy.
description: 9 pages, LaTeX, 1 eps-figure
The DNA replication initiation protein DnaD recognises a specific strand of the Bacillus subtilis chromosome origin
Creators: name: Winterhalter, Charles
name: Pelliciari, Simone
name: Stevens, Daniel
name: Fenyk, Stepan
name: Marchand, Elie
name: Cronin, Nora B
name: Soultanas, Panos
name: Costa, Tiago RD
name: Ilangovan, Aravindan
name: Murray, Heath
Publisher: name: The Francis Crick Institute
Year: 2023
Subjects: Chemical Biology & High Throughput
Structural Biology & Biophysics

description: Genome replication is a fundamental biological activity shared by all organisms. Chromosomal replication proceeds bidirectionally from origins, requiring the loading of two helicases, one for each replisome. However, the molecular mechanisms underpinning helicase loading at bacterial chromosome origins (oriC) are unclear. Here we investigated the essential DNA replication initiation protein DnaD in the model organism Bacillus subtilis. A set of DnaD residues required for ssDNA binding was identified, and photo-crosslinking revealed that this ssDNA binding region interacts preferentially with one strand of oriC. Biochemical and genetic data support the model that DnaD recognizes a new single-stranded DNA (ssDNA) motif located in oriC, the DnaD Recognition Element (DRE). Considered with single particle cryo-electron microscopy (cryo-EM) imaging of DnaD, we propose that the location of the DRE within oriC orchestrates strand-specific recruitment of helicase during DNA replication initiation. These findings significantly advance our mechanistic understanding of bidirectional replication from a bacterial chromosome origin.