cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Genetic analysis for cognitive flexibility in the trail-making test in attention deficit hyperactivity disorder patients from single nucleotide polymorphism, gene to pathway level
Creators: name: Kunlin Zhang
name: Zili Fan
name: Yufeng Wang
name: Faraone, Stephen V.
name: Yang, Li
name: Suhua Chang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Objectives: Investigation of the genetic basis of endophenotype and analysis the pathways with multiple genes of small effects might increase the understanding of the genetic basis of attention deficit hyperactivity disorder (ADHD). Here we aimed to explore the genetic basis of cognitive flexibility in ADHD at the single nucleotide polymorphism (SNP), gene and pathway levels. Methods: The trail-making test was used to test the cognitive flexibility of 788 ADHD patients. A genome-wide association analysis of cognitive flexibility was conducted for 644,166 SNPs. Results: The top SNP rs2049161 (P = 5.08e-7) involved gene DLGAP1 and the top gene CADPS2 in the gene-based analysis resulted in much literature evidence of associations with psychiatric disorders. Gene expression and network analysis showed their contribution to cognition function. The interval-enrichment analysis highlighted a potential contribution of ‘adenylate cyclase activity’ and ADCY2 to cognitive flexibility. Candidate pathway-based analysis for all SNPs found that glutamate system-, neurite outgrowth- and noradrenergic system-related pathways were significantly associated with cognitive flexibility (FDR <0.05), among which the neurite outgrowth pathway was also associated with ADHD symptoms. Conclusions: This study provides evidence for the genes and pathways associated with cognitive flexibility and facilitate the uncovering of the genetic basis of ADHD.
Geology and hydrocarbon potential of the East African continental margin: a review
Creators: name: Davison, Ian
name: Steel, Ian
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Stratigraphic correlation of the onshore Karoo Rifts in Southern Africa highlighting two important and widespread potential source rock horizons in the Artinskian and Capitanian stages of the Permian. Compiled by Matthew Taylor, personal communication.
Kashmiri Shaivism in a nutshell
Creators: name: Timalsina, Staneshwar
Publisher: name: Zenodo
Year: 2021
Subjects: sarvamnaya-oral-tradition-archive
sthaneshwar timalsina
shaivismo
sarvamnaya
timalsina
trika
vimarsha foundation
tantra
vimarsha
shaiva tantra
kashmiri shaivism
vimarsha-foundation

description: In this excerpt from his dialogue with Swami Sarvapriyananda from the Ramakrishna Order, Śaivācārya Sthaneshwar Timalsina offers a concise presentation of some fundamental Trika doctrines.
#kashmirshaivism #tantra #trika

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**** Acharya Dr. Sthaneshwar Timalsina ****
Acharya Dr. Sthaneshwar Timalsina is an esteemed traditionally consecrated teacher of Shaiva-Shakta Hindu Tantra. He is also the Endowed Chair of Indic Studies in New York, U.S.A. at Stony Brook University's College of Arts & Sciences in the Department of Asian & Asian-American Studies. Acharya Sthaneshwar founded Vimarsha Foundation as a modern school (gurukula) for teaching and reflecting on the ancient wisdom of r̥ṣis and siddhas. Through Vimarsha Foundation, a non-profit organization, Acharya Sthaneshwar teaches shastra and sādhanā to students of all backgrounds. The Vimarsha Foundation hosts free semester length courses on classic texts of the Tantric Tradition and offers many more free video and written teachings.

Original YouTube video: https://www.youtube.com/watch?v=wCTBPFh5MX0

This presentation is part of the Sarvāmnāya Oral Tradition Archive.
Vimarsha Foundation. (2025). The Sarvāmnāya Oral Tradition Archive [Data set]. Zenodo. https://doi.org/10.5281/zenodo.15188107
Investigating the feasibility and ethical implications of phenotypic screening using stem cell-derived tissue models to detect and manage disease.
Creators: name: Harris, Alexander R
name: Walker, Mary
name: Gilbert, Frederic
name: McGivern, Patrick
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified

description: Stem-cell-derived tissue models generated from sick people are being used to understand human development and disease, drug development, and drug screening. However, it is possible to detect disease phenotypes before a patient displays symptoms, allowing for their use as a disease screening tool. This raises numerous issues, some of which can be addressed using similar approaches from genetic screenings, while others are unique. One issue is the relationship between disease disposition, biomarker detection, and patient symptoms and how tissue models could be used to define disease. Other issues include decisions of when to screen, what diseases to screen for, and what treatment options should be offered.
Comparative Genomics of Members of the Genus Defluviicoccus With Insights Into Their Ecophysiological Importance
Creators: name: Bessarab, I
name: Maszenan, AM
name: Haryono, MAS
name: Arumugam, K
name: Saw, NMMT
name: Seviour, Robert
name: Williams, RBH
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 310599
subject: Genetics not elsewhere classified
classificationCode: 400410
subject: Wastewater treatment processes
classificationCode: 400411
subject: Water treatment processes

description: Members of the genus Defluviicoccus occur often at high abundances in activated sludge wastewater treatment plants designed to remove phosphorus, where biomass is subjected to alternating anaerobic feed/aerobic famine conditions, believed to favor the proliferation of organisms like Ca. Accumulibacter and other phosphate-accumulating organisms (PAO), and Defluviicoccus. All have a capacity to assimilate readily metabolizable substrates and store them intracellularly during the anaerobic feed stage so that under the subsequent famine aerobic stage, these can be used to synthesize polyphosphate reserves by the PAO and glycogen by Defluviicoccus. Consequently, Defluviicoccus is described as a glycogen-accumulating organism or GAO. Because they share a similar anaerobic phenotype, it has been proposed that at high Defluviicoccus abundance, the PAO are out-competed for assimilable metabolites anaerobically, and hence aerobic P removal capacity is reduced. Several Defluviicoccus whole genome sequences have been published (Ca. Defluviicoccus tetraformis, Defluviicoccus GAO-HK, and Ca. Defluviicoccus seviourii). The available genomic data of these suggest marked metabolic differences between them, some of which have ecophysiological implications. Here, we describe the whole genome sequence of the type strain Defluviicoccus vanusT, the only cultured member of this genus, and a detailed comparative re-examination of all extant Defluviicoccus genomes. Each, with one exception, which appears not to be a member of this genus, contains the genes expected of GAO members, in possessing multiple copies of those for glycogen biosynthesis and catabolism, and anaerobic polyhydroxyalkanoate (PHA) synthesis. Both 16S rRNA and genome sequence data suggest that the current recognition of four clades is insufficient to embrace their phylogenetic biodiversity, but do not support the view that they should be re-classified into families other than their existing location in the Rhodospirillaceae. As expected, considerable variations were seen in the presence and numbers of genes encoding properties associated with key substrate assimilation and metabolic pathways. Two genomes also carried the pit gene for synthesis of the low-affinity phosphate transport protein, pit, considered by many to distinguish all PAO from GAO. The data re-emphasize the risks associated with extrapolating the data generated from a single Defluviicoccus population to embrace all members of that genus.
Novel passive detection approach reveals low breeding season survival and apparent lactation cost in a critically endangered cave bat
Creators: name: van Harten, Emmi
name: Lawrence, R
name: Lumsden, LF
name: Reardon, T
name: Prowse, TAA
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 410499
subject: Environmental management not elsewhere classified
classificationCode: 310399
subject: Ecology not elsewhere classified
classificationCode: 300305
subject: Animal reproduction and breeding
classificationCode: 410401
subject: Conservation and biodiversity

description: Capture-mark-recapture/resight (CMR) methods are used for survival-rate studies, yet are often limited by small sample sizes. Advances in passive integrated transponder (PIT) technology have enabled passive detection or ‘resight’ of marked individuals using large antennas with greater read-ranges than previously possible. We used passively-detected resight data and CMR models to study survival rates of the southern bent-winged bat Miniopterus orianae bassanii, a critically endangered, cave-dwelling bat. Over three years, we used PIT-tagging to monitor 2966 individuals at the species’ largest breeding aggregation, using daily detection data (> 1.6 million detections) to estimate seasonal survival probabilities, structured by age, sex and reproductive status, and parameterise population projection matrices. This has hitherto been impossible using traditional CMR methods due to disturbance risk and low recapture rates. Bats exhibited lowest apparent seasonal survival over summer and autumn, particularly for reproductive females in summer (when lactating) and juveniles in autumn (after weaning), and high survival in winter. Lowest survival rates coincided with severe drought in summer–autumn 2016, suggesting that dry conditions affect population viability. Under all likely demographic assumptions, population projection matrices suggested the population is in deterministic decline, requiring urgent action to reduce extinction risk. Passively-collected resight data can now be used in combination with CMR models to provide extensive, robust information for targeted wildlife population management.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Cart. 193 (11 H 78), f. 0166v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0166v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0166v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: abbaye de Cîteaux
title: ADCO, Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Cart. 168 (11 H 66), f. 0037v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2010
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0037v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0037v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
A Cancer Exercise Toolkit Developed Using Co-Design: Mixed Methods Study.
Creators: name: Dennett, Amy
name: Tang, Youci
name: Chiu, April Sung Wai
name: Osadnik, Christian
name: Granger, Catherine L
name: Taylor, Nicholas
name: Campbell, Kristin L
name: Barton, Christian
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 420699
subject: Public health not elsewhere classified
classificationCode: 420702
subject: Exercise physiology
classificationCode: 321199
subject: Oncology and carcinogenesis not elsewhere classified

description: Background: Access to exercise therapy for cancer survivors is poor. Professional development to support exercise professionals in delivering these interventions is needed. Few online resources exist for exercise professionals to address this issue. Objective: To develop and evaluate a freely available online toolkit to support exercise professionals working with cancer survivors. Methods: A 2-phase, experience-based co-design approach was used to develop and evaluate the online toolkit. The two phases were as follows: 1) needs identification and co-design of resources and platform and 2) pilot evaluation. Four co-design workshops were conducted, transcribed, and thematically analyzed to identify key elements for the toolkit. For the pilot evaluation, a customized survey (the Determinants of Implementation Behavior Questionnaire) was distributed to exercise professionals at baseline and 3 months after launch of the online toolkit to determine its usability, utility, and effectiveness in improving their knowledge, confidence, and behavior. Results were reported as the median and interquartile range and changes were calculated using non-parametric tests. Website analytics described site usage after the initial evaluation. Results: Twenty-five exercise professionals participated in co-designing 8 key elements of the online Cancer Exercise Toolkit: the homepage and pages for getting started, screening and safety, assessment, exercise prescription, education, locations, and resources. For the pilot evaluation, 277/320 respondents (87% of whom were physiotherapists) from 26 countries completed the survey at baseline, with 58 exercise professionals completing follow-up surveys at 3 months. Exercise professionals' knowledge, skills, and confidence in delivering exercise therapy to cancer survivors increased 3 months after baseline (items 1, 6, and 8: median score 5, IQR 3 to 6) to follow-up (items 1 and 6: median score 6, IQR 5 to 6; item 8: median score 5, IQR 5 to 7; P < .001) on a 1 to 7 Likert scale. Most participants (35/44, 80%) agreed or strongly agreed they would recommend the toolkit to colleagues. In the 6 months following the pilot evaluation, the toolkit received an average of 866 views per month. Conclusions: The co-designed online Cancer Exercise Toolkit was a useful resource for exercise professionals that may increase their knowledge, skills, and confidence in providing exercise therapy to cancer survivors.
title: Patchy worm-like micelles: solution structure studied by small-angle neutron scattering
Creators: name: Rosenfeldt, Sabine
name: Lüdel, Frank
name: Schulreich, Christoph
name: Hellweg, Thomas
name: Radulescu, Aurel
name: Schmelz, Joachim
name: Schmalz, Holger
name: Harnau, Ludger
Publisher: name: University of Bayreuth
Year: 2012
Subjects: subject: Single Lamella Nanoparticles
subject: Block-CoPolymers
subject: Janus Particles
subject: Core Micelles
subject: Polymer
subject: Polyethylene
subject: Brushes
subject: Complex
subject: Blends
subject: Corona
subject: 530
subject: 540

description: Triblock terpolymers exhibit a rich self-organization behavior including the formation of fascinating cylindrical core-shell structures with a phase separated corona. After crystallization-induced self-assembly of polystyrene-block-polyethylene-block-poly(methyl methacrylate) triblock terpolymers (abbreviated as SEMs = Styrene-Ethylene-Methacrylates) from solution, worm-like core-shell micelles with a patchy corona of polystyrene and poly(methyl methacrylate) were observed by transmission electron microscopy. However, the solution structure is still a matter of debate. Here, we present a method to distinguish in situ between a Janus-type (two faced) and a patchy (multiple compartments) configuration of the corona. To discriminate between both models the scattering intensity must be determined mainly by one corona compartment. Contrast variation in small-angle neutron scattering enables us to focus on one compartment of the worm-like micelles. The results validate the existence of the patchy structure also in solution.
Allied Health Student Engagement in Telehealth Clinical Placements: A Rapid Review
Creators: name: Bridgman, Kate
name: Erickson, Shane
name: Furlong, Lisa
name: Bird, Adam
Publisher: name: La Trobe
Year: 2022

description: ABSTRACT Purpose: The engagement of allied health students in telehealth consultations whilst on clinical placement has rapidly increased due to the disruption caused by COVID-19. While this is understandable given the circumstances, it has occurred on the largely unfounded assumption that utilising telehealth is pedagogically appropriate to supplement or replace assessed placements. Method: This rapid review used the Cochrane rapid review methodology to synthesise the literature relating to the perspectives of allied health students whilst on clinical placements utilising telehealth. Results: A systematic search and selection process found three studies. In summary, the combined findings of the research suggest that student perspectives were generally positive, and several important benefits were reported, including being able to improve knowledge and skills, and reduce anxiety for some consultations. However, students acknowledged that some consultations were considerably more difficult to undertake without being in the same physical space as clients. Conclusions: The methodological quality of these three papers was inconsistent, and collectively the area clearly needs more evidence to support the transition of face-to-face to telehealth environments. Recommendations: Based on broader telehealth literature, the authors propose several recommendations to meet the immediate challenge of insufficient guiding research evidence. These include deconstructing telehealth placements into discrete clinical placement elements, using education theory to support student clinicians to implement a proactive, integrated approach to adopting telehealth as a standard service modality, and investing in and developing infrastructure, policy, systems, education, and training in an explicit, systematic manner. The use of telehealth within allied health clinical placements is here to stay, but considerable work is needed to prepare students for this environment as well as triaging and progressively scaffolding their experiences. Keywords: telehealth, allied health, clinical placement, work integrated learning
A Mental Health Chatbot with Cognitive Skills for Personalised Behavioural Activation and Remote Health Monitoring
Creators: name: Rathnayaka Mudiyanselage, Prabod Manuranga
name: Mills, Nishan
name: Burnett, Donna
name: De Silva, Daswin
name: Alahakoon, Damminda
name: Gray, Richard
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 340199
subject: Analytical chemistry not elsewhere classified
classificationCode: 460699
subject: Distributed computing and systems software not elsewhere classified
classificationCode: 420313
subject: Mental health services
classificationCode: 460299
subject: Artificial intelligence not elsewhere classified

description: Mental health issues are at the forefront of healthcare challenges facing contemporary human society. These issues are most prevalent among working-age people, impacting negatively on the individual, his/her family, workplace, community, and the economy. Conventional mental healthcare services, although highly effective, cannot be scaled up to address the increasing demand from affected individuals, as evidenced in the first two years of the COVID-19 pandemic. Conversational agents, or chatbots, are a recent technological innovation that has been successfully adapted for mental healthcare as a scalable platform of cross-platform smartphone applications that provides first-level support for such individuals. Despite this disposition, mental health chatbots in the extant literature and practice are limited in terms of the therapy provided and the level of personalisation. For instance, most chatbots extend Cognitive Behavioural Therapy (CBT) into predefined conversational pathways that are generic and ineffective in recurrent use. In this paper, we postulate that Behavioural Activation (BA) therapy and Artificial Intelligence (AI) are more effectively materialised in a chatbot setting to provide recurrent emotional support, personalised assistance, and remote mental health monitoring. We present the design and development of our BA-based AI chatbot, followed by its participatory evaluation in a pilot study setting that confirmed its effectiveness in providing support for individuals with mental health issues.
Seasonal and functional variation in the trophic base of intermittent Alpine streams
Creators: name: Siebers, Andre
name: Paillex, A
name: Robinson, CT
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified
classificationCode: 310304
subject: Freshwater ecology

description: In high-altitude Alpine streams, seasonal cycles of snowmelt, glacial melt, and rainfall drive variation in the availability of algal food resources. Yet, high-altitude streams also exhibit varying degrees of flow intermittency, ranging from solely winter-drying streams to others that dry periodically throughout summer and autumn. These environmental drivers may interact in different ways to determine the functional trophic base of macroinvertebrates inhabiting high-altitude streams. Here, we estimated the proportional contribution of autochthonous resources to the assimilated diets of benthic macroinvertebrates in 26 headwater streams of Val Roseg, a high Alpine glacial catchment, using stable isotope analysis (δ13C and δ15N) of different macroinvertebrate families and their potential food sources. We compared dietary estimates along a gradient of flow intermittency and across three seasons (Alpine spring, summer, and autumn). Assimilation from autochthonous sources was highest for collector-gatherers and filter feeders in spring, and for grazers in summer. Grazers had higher estimated assimilation from autochthonous sources in intermittent streams than in perennial streams, particularly in summer, while collector-gatherers showed little effect of flow intermittency on dietary estimates. However, responses were highly taxon-specific, with different responses to variation in flow intermittency and season across families within functional groups. Our results suggest that frequent summer-drying events represent tradeoffs between greater access to algal food resources and a higher risk of desiccation, but that differing life history and functional feeding traits across macroinvertebrate taxa drive marked variation in the risks or benefits associated with inhabitants of drying streams.
Lettre de Etienne et Edmé Piestre et Cormon à Jean-François Séguier, 1780-11-09
Creators: name: Piestre et Cormon, Etienne et Edmé
name: Cormon, Etienne Et Edmé Piestre Et
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Librairie

description: [transcription] Lyon, le 9e novembre 1780.

Monsieur,

Nous avons l'honneur de vous donner avis que nous venons de céder toutes nos affaires à MM. Piestre et Cormon, Libraires de Lyon. n'ayant point d'enfants mâles à qui transmettre un commerce que notre famille a suivi de père en fils depuis deux siècles & demi, nous nous sommes déterminés à le remettre en entier auxdits Sieurs Piestre et Cormon qui géraient depuis plusieurs années notre établissement de Lyon, & qui ont toujours mérité notre confiance. Nous leur avons remis généralement tous les livres qui composaient nos fonds de Librairie de Genève & de Lyon, ainsi ce sera précisément le même commerce continué sous des noms différents : ils se font aussi chargés de la suite des comptes que nous avions avec nos divers correspondants. Nous vous prions donc, Monsieur, de vous adresser à eux pour toutes les choses pour lesquelles vous nous auriez fait l'honneur de vous adresser à nous.

Nous sommes, Monsieur,

Vos très humbles & très obéissants serviteurs,

Les frères de Tournes

Monsieur Séguier est prié en recevant cette lettre ci-dessus de recevoir en même temps l'assurance des respects des frères de Tournes : en quittant les affaires de librairie, ils conserveront pour lui le zèle et la considération qu'il mérite et s'il a quelque chose à faire à Genève ou dans les environs, il pourra toujours s'y adresser à M. Samuel de Tournes qui se fera un plaisir et un devoir d'exécuter vos ordres.

Nous remarquons que nous vous avons fait tenir environ 31 lt. de trop : nous chargerons Messieurs Piestre et Cormon de vous en tenir compte de la manière que vous souhaitez.

Lesdits.

Nîmes Monsieur Séguier
description: [personnes citées] Samuel et Donat-Louis De Tournes
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 312_1, fol. 120
description: Source: ark:/12148/btv1b10015922t
Key Stakeholder Priorities for the Review and Update of the Australian Guide to Diagnosis of Fetal Alcohol Spectrum Disorder: A Qualitative Descriptive Study
Creators: name: Hayes, Nicole
name: Akison, Lisa K
name: Goldsbury, Sarah
name: Hewlett, Nicole
name: Elliott, Elizabeth J
name: Finlay-Jones, Amy
name: Shanley, Dianne C
name: Bagley, Kerryn
name: Crawford, Andi
name: Till, Haydn
name: Crichton, Alison
name: Friend, Rowena
name: Moritz, Karen M
name: Mutch, Raewyn
name: Harrington, Sophie
name: Webster, Andrew
name: Reid, Natasha
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 420699
subject: Public health not elsewhere classified

description: Since the 2016 release of the Australian Guide to the Diagnosis of Fetal Alcohol Spectrum Disorder (FASD), considerable progress has been made in the identification and diagnosis of the disorder. As part of a larger process to review and update the Guide, the aim of this study was to identify review priorities from a broad range of stakeholders involved in the assessment and diagnosis of FASD. Sixty-two stakeholders, including healthcare practitioners, researchers, other specialists, individuals with cultural expertise, lived experience and consumer representatives com-pleted an online survey asking them to describe up to five priorities for the review of the Australian Guide to the Diagnosis of FASD. A total of 267 priorities were described. Content analysis of responses revealed priority areas relating to diagnostic criteria (n = 82, 30.7%), guideline content (n = 91, 34.1%), guideline dissemination (n = 15, 5.6%) and guideline implementation (n = 63, 23.6%). Other considerations included prevention and screening of FASD (n = 16, 6%). Engaging stakehold-ers in setting priorities will ensure the revised Australian Guide can be as relevant and meaningful as possible for the primary end-users and that it meets the needs of individuals with lived experience who will be most affected by the diagnosis.
Exploring beyond the limit: How comparative stochastic performance affects retesting outcomes in six commercial SARS CoV-2 nucleic acid amplification tests.
Creators: name: Chan, Hiu Tat
name: Keung, Marco HT
name: Nguyen, Ivy
name: Ip, Ellen LO
name: Chew, Su M
name: Siler, Danielle
name: Saville, Marion
name: Hawkes, David
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 490599
subject: Statistics not elsewhere classified
classificationCode: 490502
subject: Biostatistics
classificationCode: 490510
subject: Stochastic analysis and modelling

description: Objectives: To examine the comparative stochasticity profile of six commercial SARS-CoV-2 nucleic acid amplification tests (NAATs) and how this may affect retesting paradigms. Methods: Commercial quality control (QC) material was serially diluted in viral transport media to create a panel covering 10–10,000 copies/ml. The panel was tested across six commercial NAATs. A subset of high cycle threshold results was retested on a rapid PCR assay to simulate retesting protocols commonly used to discriminate false positives. Results: Performance beyond the LOD differed among assays, with three types of stochasticity profiles observed. The ability of the rapid PCR assay to reproduce a true weak positive specimen was restricted to its own stochastic performance at the corresponding viral concentration. Conclusion: Stochastic performance of various NAATs overlap across low viral concentrations and affect retesting outcomes. Relying on retesting alone to discriminate false positives risk missing true positives even when a more sensitive assay is deployed for confirmatory testing.
Supplementary Material from Native freshwater species get out of the way: Prussian carp (Carassius gibelio) impacts both fish and benthic invertebrate communities in North America
Creators: name: Ruppert, Jonathan L. W.
name: Docherty, Cassandra
name: Neufeld, Kenton
name: Hamilton, Kyle
name: MacPherson, Laura
name: Poesch, Mark S.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences

description: Prussian carp (Carassius gibelio) are one of the most noxious non-native species in Eurasia. Recently, Prussian carp, a non-native freshwater fish species, were genetically confirmed in Alberta, Canada and have been rapidly expanding their range in North America since establishment. Given their rapid range expansion, there is an increasing need to determine how Prussian carp may impact native species. We assessed the severity of the Prussian carp invasion by (i) determining their impact on fish communities, (ii) assessing their impact on benthic invertebrate communities, (iii) evaluating if Prussian carp alter abiotic conditions and (iv) identifying where we find higher abundances of Prussian carp. When Prussian carp were established, we found significant changes to the fish community. Correspondingly, the degree of impact to benthic invertebrate communities was related to the stage of invasion (none, early or recent), where changes in fish communities were significantly concordant with changes in benthic invertebrate communities. Finally, we found that higher abundances of Prussian carp were significantly associated with lower abundances of a majority of native fish species. Altogether, using three lines of evidence, we determine that Prussian carp can have wide-ranging impacts on freshwater ecosystems in North America, pressing the need for management intervention.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Cart. 185 (11 H 70), f. 0293r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0293r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0293r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
De novo-designed transmembrane domains tune engineered receptor functions
Creators: name: Elazar, A
name: Chandler, NJ
name: Davey, AS
name: Weinstein, JY
name: Nguyen, JV
name: Trenker, R
name: Cross, RS
name: Jenkins, Misty
name: Call, MJ
name: Call, ME
name: Fleishman, SJ
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified

description: De novo-designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. We developed a de novo design strategy for generating programmed membrane proteins (proMPs): single-pass α-helical TMDs that self-assemble through computationally defined and crystallographically validated interfaces. We used these proMPs to program specific oligomeric interactions into a chimeric antigen receptor (CAR) that we expressed in mouse primary T cells and found that both in vitro CAR T cell cytokine release and in vivo antitumor activity scaled linearly with the oligomeric state encoded by the receptor TMD, from monomers up to tetramers. All programmed CARs stimulated substantially lower T cell cytokine release relative to the commonly used CD28 TMD, which we show elevated cytokine release through lateral recruitment of the endogenous T cell costimulatory receptor CD28. Precise design using orthogonal and modular TMDs thus provides a new way to program receptor structure and predictably tune activity for basic or applied synthetic biology.
КОМПЛЕКСНАЯ ОЦЕНКА РАСПРОСТРАНЕННОСТИ ПАТОЛОГИИ СРЕДИ ЛИЦ ДОПРИЗЫВНОГО И ПРИЗЫВНОГО ВОЗРАСТА
Creators: name: Шведов Евгений Геннадьевич
name: Бабенко Анатолий Иванович
Publisher: name: Современные проблемы здравоохранения и медицинской статистики
Year: 2019
Subjects: заболеваемость
медицинское освидетельствование
интегрированная оценка
лица допризывного и призывного возраста

description: Введение. Разработка стратегии снижению распространенности заболеваний, ограничивающих годность к военной службе, предусматривает использование информационных баз медицинских организаций и военных комиссариатов. Необходимо определить, как этот информационный комплекс применять для стратегического планирования в здравоохранении. Материал и методы. Материалы исследования включали данные о заболеваемости подростков Новосибирской области в возрасте 15–17 лет за период 2012–2017 гг. с интегрированной оценкой показателей общей, первичной и диспансеризуемой заболеваемости на основе расчетов коэффициентов относительной важности. По данным военно-врачебной комиссии военного комиссариата Новосибирской области о результатах медицинского освидетельствования 285,5 тыс. лиц допризывного возраста и 258,0 тыс. лиц призывного возраста проведен анализ заболеваемости, ограничивающей годность к военной службе. Углубленно изучены материалы 1204 протоколов медицинского освидетельствования призывников с установлением распространенности патологии. На основе интегрирования показателей всех информационных баз определена значимость основных классов болезней. Результаты. Установлено, что ведущими заболеваниями, снижающими годность к военной службе, являются болезни костно-мышечной системы и соединительной ткани; эндокринной системы, расстройства питания и нарушения обмена веществ; органов дыхания; системы кровообращения; глаза и его придаточного аппарата; нервной системы; органов пищеварения; психические расстройства и расстройства поведения, составляющие 92,5 % значимости от всего объема патологии. Соответственно этому приоритетными медицинскими службами, определяющими стратегию медицинской помощи при снижении потерь обороноспособного потенциала, являются ортопедическая, эндокринологическая, пульмонологическая, психиатрическая, неврологическая, кардиологическая, офтальмологическая и гастроэнтерологическая. Вывод. Проведенное исследование позволило определить количественную значимость отдельных классов болезней на различных этапах их выявления для комплексной оценки распространенности патологии среди лиц допризывного и призывного возраста.
title: The Natural History of the Naked Goby Gobiosoma bosci (Perciformes: Gobiidae)
Creators: name: Nero, Leonard L.
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1976

description: The purpose of this study was to contribute to the knowledge of re ­ production, growth, age, abundance, habitat preference, feeding habit and behavior of the naked goby, Gobiosoma Bosci.

Monthly collections were made from January through December. 1974 in Deary Cove a apart of the Lynnhaven estuary, Virginia Beach, Virginia. All fish were measured and sexed in the field.

Most were returned to the population, the remainder. were removed for food habit analyses, determination of fecundity, degree of gonadal maturity and aging. Habitat­ preference and abundance were determined in the field.

Gobiosoma Bosci appears to be an annual species. spawning from April to about August in Deary Cove. Fecundity ranged from 688-1418 in fifteen specimens examined. Growth is more rapid in young fish. and males than in older fish and females. Population densities were found to be 8.0 fish/ m2 in an area with 25% suitable cover. The naked goby is a-sedentary facultative object dweller. The most important food item in the popula­tion investigated was polychaetas with the rest of its diet reflecting functional opportunism. The naked goby does not display territoriality except during spawning and nest guarding. A color anomaly is noted dorsal and caudal fins had black margins.
Mathematics Teacher's Job Satisfaction in Middle School in Jeddah, Saudi Arabia
Creators: name: KHALED MOHMMAD A ALZHRANI
Publisher: name: Monash University
Year: 2017
Subjects: Education

description: This research examines Mathematics teachers’ job satisfaction levels in the four dimensions of job satisfaction (administrative support, workplace atmosphere, teaching efficacy and students’ behavior) and its relation to students’ achievements in Middle schools in Jeddah, Saudi Arabia.
title:  Les traductions des romans de Zola et la réception du naturalisme en Chine (1871-1949)
Creators: name: Lombardi, Rosa
Publisher: name: RomaTrE-Press
Year: 2018

description: Lo studio si propone di illustrare le dinamiche che preparano e accompagnano la ricezione delle teorie naturaliste e la traduzione delle principali opere di Zola in Cina nella prima metà del Novecento. L’analisi di scritti teorici, di prefazioni e postfazioni alle edizioni cinesi delle opere di Zola, firmate da noti traduttori e scrittori dell’epoca, sembra indicare che la scelta di introdurre in Cina il Naturalismo fu dettata dalla volontà di creare un nuovo e moderno canone letterario che rispondesse alle esigenze del periodo storico. L’acceso dibattito sulle teorie di Zola che precedette la traduzione delle sue opere, portò a un adattamento e sinizzazione del Naturalismo, attraverso l’esclusione degli aspetti considerati negativi che ne avrebbero condizionato la ricezione in Cina.
description: Traduire Zola du XIXesiècle à nos jours
Factors associated with patient experiences of the burden of using medicines and health-related quality of life: A cross-sectional study.
Creators: name: Chen, Won Sun
name: Islam, MD Rafiqul
name: Ambepitiya, Sajini
name: Sim, William
name: Yiu, Wai
name: Carey, Joseph
name: Ogden, Edward
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 420699
subject: Public health not elsewhere classified

description: Objective Polypharmacy, defined as the concurrent use of multiple medications, is a growing concern globally. This study aimed to identify the significant factors that predict the perceived burden of medication and health-related quality of life. Methods Adults, aged 18 years and above who have used at least two regular medicines, were invited to complete the study questionnaires between June and October 2019. Multiple linear regression analysis was conducted to identify significant predictors for perceived burden of medication and health-related quality of life. Results A total of 119 participants completed this study. The average age of the participants was 63 years (SD±16 years). Factors significantly predicting perceived burden of medication were participants’ current health condition (p = 0.001), overall burden of treatment (p<0.001) and being hypertensive (p = 0.037). Similarly, participants’ current health condition (p<0.001) and overall burden of treatment (p = 0.086) were significant predictors for perceived health-related quality of life. Conclusions This study revealed that hypertensive participants in poor health tended to experience higher perceived burden of medication, which in turn was found to be correlated with lower perceived health-related quality of life.
Belowground mechanism reveals climate change impacts on invasive clonal plant establishment
Creators: name: Bam, Surendra
name: Ott, JP
name: Butler, JL
name: Xu, L
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 410299
subject: Ecological applications not elsewhere classified
classificationCode: 410499
subject: Environmental management not elsewhere classified
classificationCode: 310399
subject: Ecology not elsewhere classified

description: Climate change and disturbance can alter invasion success of clonal plants by differentially affecting the clonal traits influencing their establishment as young plants. Clonal traits related to the vegetative reproduction of native Pascopyrum smithii and non-native Bromus inermis grass seedlings were evaluated under altered precipitation frequencies and a single grazing event. Pascopyrum smithii maintained similar vegetative reproduction under three simulated precipitation frequencies whereas B. inermis vegetative reproduction declined as precipitation became more intermittent. Vegetative reproduction of the non-native B. inermis was greater than the native P. smithii under all simulated precipitation frequencies except the most intermittent scenario. A single grazing event did not affect either species’ response to intra-annual precipitation variability but did slightly reduce their clonal growth and increase their bud dormancy. In young plants, clonal traits of the invasive grass favored its superior expansion and population growth compared to the native grass except under the most severe climate change scenario. Grassland restoration using native P. smithii seeds would be successful in most years due to its resilient clonal growth in a changing climate. Clonal infrastructure development in young plants is critical to clonal plant establishment and persistence in a changing climate and under disturbed conditions.
The influence of hardness at varying pH on zinc toxicity and lability to a freshwater microalga, Chlorella sp.
Creators: name: Price, GAV
name: Stauber, Jenny
name: Holland, Aleicia
name: Koppel, DJ
name: Van Genderen, EJ
name: Ryan, AC
name: Jolley, DF
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 349999
subject: Other chemical sciences not elsewhere classified

description: Zinc is an essential element for aquatic organisms, however, activities such as mining and refining, as well as zinc's ubiquitous role in modern society can contribute to elevated environmental concentrations of zinc. Water hardness is widely accepted as an important toxicity modifying factor for metals in aquatic systems, though other factors such as pH are also important. This study investigated the influence of increasing water hardness, at three different pH values (6.7, 7.6 and 8.3), on the chronic toxicity of zinc to the growth rate of a microalgae, Chlorella sp. Zinc toxicity decreased with increasing hardness from 5 to 93 mg CaCO3 L−1 at all three pH values tested. The 72 h growth rate inhibition EC50 values ranged from 6.2 μg Zn L−1 (at 5 mg CaCO3 L−1, pH 8.3) to 184 μg Zn L−1 (at 92 mg CaCO3 L−1, pH 6.7). Increases in hardness from 93 to 402 mg CaCO3 L−1 generally resulted in no significant (p > 0.05) reduction in zinc toxicity. DGT-labile zinc measurements did not correspond with the observed changes in zinc toxicity as hardness was varied within a pH treatment. This suggests that cationic competition from increased hardness is decreasing zinc toxicity, rather than changes in metal lability. This study highlighted that current hardness algorithms used in water quality guidelines may not be sufficiently protective of sensitive species, such as Chlorella sp., in high hardness waters.