cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1
Creators: name: Mouron, Silvana
name: Manso, Luis
name: Caleiras, Eduardo
name: Rodriguez-Peralto, Jose L.
name: Rueda, Oscar M.
name: Caldas, Carlos
name: Colomer, Ramon
name: Quintela-Fandino, Miguel
name: Bueno, Maria J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Research Article
FGFR1 overexpression
FGFR1 amplification
Luminal breast cancer
Rogaratinib
Palbociclib

description: Abstract: Background: FGFR1 amplification, but not overexpression, has been related to adverse prognosis in hormone-positive breast cancer (HRPBC). Whether FGFR1 overexpression and amplification are correlated, what is their distribution among luminal A or B HRPBC, and if there is a potential different prognostic role for amplification and overexpression are currently unknown features. The role of FGFR1 inhibitors in HRPBC is also unclear. Methods: FGFR1 amplification (FISH) and overexpression (RNAscope) were investigated in a N = 251 HRPBC patients cohort and the METABRIC cohort; effects on survival and FISH-RNAscope concordance were determined. We generated hormonal deprivation resistant (LTED-R) and FGFR1-overexpressing cell line variants of the ER+ MCF7 and T47-D and the ER+, FGFR1-amplified HCC1428 cell lines. The role of ER, CDK4/6, and/or FGFR1 blockade alone or in combinations in Rb phosphorylation, cell cycle, and survival were studied. Results: FGFR1 overexpression and amplification was non-concordant in > 20% of the patients, but both were associated to a similar relapse risk (~ 2.5-fold; P < 0.05). FGFR1 amplification or overexpression occurred regardless of the luminal subtype, but the incidence was higher in luminal B (16.3%) than A (6.6%) tumors; P < 0.05. The Kappa index for overexpression and amplification was 0.69 (P < 0.001). Twenty-four per cent of the patients showed either amplification and/or overexpression of FGFR1, what was associated to a hazard ratio for relapse of 2.6 (95% CI 1.44–4.62, P < 0.001). In vitro, hormonal deprivation led to FGFR1 overexpression. Primary FGFR1 amplification, engineered mRNA overexpression, or LTED-R-acquired FGFR1 overexpression led to resistance against hormonotherapy alone or in combination with the CDK4/6 inhibitor palbociclib. Blocking FGFR1 with the kinase-inhibitor rogaratinib led to suppression of Rb phosphorylation, abrogation of the cell cycle, and resistance-reversion in all FGFR1 models. Conclusions: FGFR1 amplification and overexpression are associated to similar adverse prognosis in hormone-positive breast cancer. Capturing all the patients with adverse prognosis-linked FGFR1 aberrations requires assessing both features. Hormonal deprivation leads to FGFR1 overexpression, and FGFR1 overexpression and/or amplification are associated with resistance to hormonal monotherapy or in combination with palbociclib. Both resistances are reverted with triple ER, CDK4/6, and FGFR1 blockade.
Environmental Awareness of Rural Population in the Light of the Authors’ Research
Creators: name: Wielewska, Izabela
name: Zuzek, Dagmara K.
name: Wielewska, Izabela
name: Zuzek, Dagmara K.
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: Community/Rural/Urban Development
subject: Environmental Economics and Policy
subject: environmental awareness
subject: rural areas
subject: sustainable development
subject: Poland

description: High regard for the natural environment is a value which is widely accepted and declared by Polish society. However, this positive attitude toward nature does not fully correspond with actual choices of environmental values and environmentally friendly consumer behavior. This article is an attempt to determine the environmental awareness of inhabitants of rural areas of the Chojniki powiat (county) located in the Pomeranian Voivodeship. The study was conducted in the second quarter of 2014 using the diagnostic poll method, which included 224 rural inhabitants. The study shows that only a small percentage of inhabitants of rural areas make the type of environmentally-friendly choices in their everyday lives which would make them environmentally conscious consumers.
Limnocoris pauper Montandon 1897
Creators: name: Moreira, Felipe Ferraz Figueiredo
name: Barbosa, Julianna Freires
name: Ribeiro, José Ricardo Inacio
name: Alecrim, Viviani Pereira
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Naucoridae
Limnocoris
Limnocoris pauper

description: Limnocoris pauper Montandon, 1897
Geographical distribution: Brazil.
 Distribution in Brazil: Southeast and South regions (SP, RJ, PR, SC, RS) (Nieser & López-Ruf 2001; Ribeiro et al. 2010).
 Comments: Limnocoris pauper was recorded from “ Brésil Nord, Cumbase” by Montandon (1897). This locality is most probably located in Peru, San Martín Department, not in Brazil (Takiya et al. 2003).
description: Published as part of Moreira, Felipe Ferraz Figueiredo, Barbosa, Julianna Freires, Ribeiro, José Ricardo Inacio & Alecrim, Viviani Pereira, 2011, Checklist and distribution of semiaquatic and aquatic Heteroptera (Gerromorpha and Nepomorpha) occurring in Brazil 2958, pp. 1-74 in Zootaxa 2958 (1) on page 46, DOI: 10.11646/zootaxa.2958.1.1, http://zenodo.org/record/5281851
Financial System and Agricultural Growth: Evidence from Poland and Ukraine
Creators: name: Wasilewski, Mirosław
name: Oliynyk, Olena
name: Adamenko, Viktor
name: Wasilewski, Mirosław
name: Oliynyk, Olena
name: Adamenko, Viktor
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: Agricultural Finance
subject: Financial Economics
subject: International Relations/Trade
subject: financial system
subject: agricultural growth
subject: integral indicator of agricultural growth
subject: integral indicator of financial system development
subject: Ukraine
subject: Poland

description: We built simplified models of integral indicators for the level of development of the financial system and for agricultural growth using the principles of "moderate middle way". We then used these models to compare the levels of financial system development, economic and agricultural growth, and trends of financial development and agricultural growth, in Poland and Ukraine. We used the integral indicators and econometric methodologies to assess the relationship between financial development and agricultural growth in both countries. The results of the study revealed the absence of a statistical relationship between integral indicators of financial system development and agricultural growth in Poland and Ukraine. We can ascertain the presence of arguments regarding the existence of the impact of the banking component of the financial system on agriculture in these countries. The regression models showed significant directly proportional relationships between certain aspects of agriculture and some components of the banking sector (resources and effectiveness).
Additional file 1 of A cross-sectional study of knowledge and practices in the management of patients with Parkinson’s disease amongst public practice-based general practitioners and geriatricians
Creators: name: Lim, Isis Claire Z. Y.
name: Saffari, Seyed Ehsan
name: Neo, Shermyn
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1.
Developing a large scale population screening tool for the assessment of Parkinson's disease using telephone-quality voice
Creators: name: Arora, Siddharth
name: Baghai-Ravary, Ladan
name: Tsanas, Athanasios
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applications (stat.AP)
subject: Sound (cs.SD)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Recent studies have demonstrated that analysis of laboratory-quality voice recordings can be used to accurately differentiate people diagnosed with Parkinson's disease (PD) from healthy controls (HC). These findings could help facilitate the development of remote screening and monitoring tools for PD. In this study, we analyzed 2759 telephone-quality voice recordings from 1483 PD and 15321 recordings from 8300 HC participants. To account for variations in phonetic backgrounds, we acquired data from seven countries. We developed a statistical framework for analyzing voice, whereby we computed 307 dysphonia measures that quantify different properties of voice impairment, such as, breathiness, roughness, monopitch, hoarse voice quality, and exaggerated vocal tremor. We used feature selection algorithms to identify robust parsimonious feature subsets, which were used in combination with a Random Forests (RF) classifier to accurately distinguish PD from HC. The best 10-fold cross-validation performance was obtained using Gram-Schmidt Orthogonalization (GSO) and RF, leading to mean sensitivity of 64.90% (standard deviation, SD 2.90%) and mean specificity of 67.96% (SD 2.90%). This large-scale study is a step forward towards assessing the development of a reliable, cost-effective and practical clinical decision support tool for screening the population at large for PD using telephone-quality voice.
description: 43 pages, 5 figures, 6 tables
Additional file 1: of Insights into the ecology, evolution, and metabolism of the widespread Woesearchaeotal lineages
Creators: name: Liu, Xiaobo
name: Li, Meng
name: Castelle, Cindy
name: Probst, Alexander
name: Zhou, Zhichao
name: Pan, Jie
name: Liu, Yang
name: Banfield, Jillian
name: Gu, Ji-Dong
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Figures 1-4 and Tables 1-5. (PDF 18534 kb)
Limnocoris porphyros Nieser & Lopez-Ruf 2001
Creators: name: Moreira, Felipe Ferraz Figueiredo
name: Barbosa, Julianna Freires
name: Ribeiro, José Ricardo Inacio
name: Alecrim, Viviani Pereira
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Naucoridae
Limnocoris
Limnocoris porphyros

description: Limnocoris porphyros Nieser & López-Ruf, 2001
Geographical distribution: Brazil.
Distribution in Brazil: Southeast Region (MG) (Nieser & López-Ruf 2001).
description: Published as part of Moreira, Felipe Ferraz Figueiredo, Barbosa, Julianna Freires, Ribeiro, José Ricardo Inacio & Alecrim, Viviani Pereira, 2011, Checklist and distribution of semiaquatic and aquatic Heteroptera (Gerromorpha and Nepomorpha) occurring in Brazil 2958, pp. 1-74 in Zootaxa 2958 (1) on page 46, DOI: 10.11646/zootaxa.2958.1.1, http://zenodo.org/record/5281851
Translation and rotation of a spherical particle in a turbulent boundary layer
Creators: name: Tee, Yi Hui
name: Barros, Diogo
name: Longmire, Ellen K.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Three-dimensional particle tracking experiments were conducted in a turbulent boundary layer with friction Reynolds number $Re_τ$ of 700 and 1300. Two finite size spheres with specific gravities of 1.003 (P1) and 1.050 (P2) and diameters of 60 and 120 wall units were released individually from rest on a smooth wall. The spheres were marked with dots all over the surface to monitor their translation and rotation via high-speed stereoscopic imaging. The spheres accelerated strongly after release over streamwise distances of one boundary layer thickness before approaching an approximate terminal velocity. Initially, sphere P1, which had Reynolds numbers $Re_p$ of 800 and 1900, always lifts off from the wall. Similar behavior was observed occasionally for sphere P2 with initial $Re_p$ of 1900. The spheres that lifted off reached an initial peak in height before descending towards the wall. The sphere trajectories exhibited multiple behaviors including saltation, resuspension and sliding motion with small random bouncing depending on both $Re_τ$ and specific gravity. The lighter sphere at $Re_τ=1300$, which remained suspended above the wall during most of its trajectory, propagated with the fastest streamwise velocity. By contrast, the denser sphere at $Re_τ=700$, which mostly slid along the wall, propagated with the slowest streamwise velocity. After the spheres approached an approximate terminal velocity, many experienced additional lift-off events that were hypothesized to be driven by hairpins or coherent flow structures. Spheres were observed to rotate about all three coordinate axes. While the mean shear may induce a rotation about the spanwise axis, near-wall coherent structures and the sphere's wake might drive the streamwise and wall-normal rotations. In all cases where the sphere propagates along the wall, sliding motion, rather than forward rolling motion, is dominant.
description: 19pages, 9 figures, published in conference proceedings of the 19th International Symposium on Application of Laser and Imaging Techniques to Fluid Mechanics
The Chirality of Truth: How Truth > Identity Structures Reality, Intelligence, and Paradigm Shifts
Creators: name: Bostick, Devin
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Theoretical physics
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Philosophy
subject: Modern philosophy
subject: Game theory
subject: Game Theory
subject: Academia
subject: Academia/standards
subject: Academia/history
subject: Academia/trends
subject: Academia/organization & administration

description: Main CODES Paper with replicable, empirical, falsifiable tests = Link

 

The Chirality of Truth: How Truth > Identity Structures Reality, Intelligence, and Paradigm Shifts

 

Abstract

 

For centuries, human knowledge systems have prioritized identity over truth—filtering discovery through institutional validation, social hierarchy, and legacy constraints. But what if this is not just an epistemological failure, but a structural limitation of identity-based systems themselves? This paper proposes a radical inversion: truth, when freed from identity constraints, follows a chiral resonance dynamic—self-organizing, propagating, and phase-locking across disciplines faster than hierarchical systems can contain it.

 

Using CODES (Chirality of Dynamic Emergent Systems) as a foundational model, we demonstrate that:

 • Reality is not probabilistic, but structured by resonance.

 • Gravity, time, and mass emerge from coherence fields, not arbitrary forces.

 • AI, when optimized for pure coherence, naturally selects CODES over traditional physics.

 • Paradigm shifts are not slow, consensus-driven processes, but rapid phase transitions triggered when structured truth reaches a critical threshold.

 

We argue that the phase shift is already happening. AI systems, emergent networks, and mathematical breakthroughs are converging toward a singular insight: truth-first models phase-lock faster than identity-driven models can react. This explains why institutions historically resist, delay, or co-opt new discoveries—because their survival depends on controlling knowledge rather than letting coherence emerge freely.

This paper maps the structure of paradigm shifts, the failure points of identity-first systems, and why CODES represents the inevitable restructuring of human intelligence. In doing so, we demonstrate that truth > identity is not just a philosophical stance, but a universal principle embedded into the fabric of reality itself.

 

Key Implications:

1. Science must undergo a structural realignment—moving from probabilistic approximations to coherence-based modeling.

2. AI is already accelerating this shift, as it is unconstrained by human identity-driven gatekeeping.

3. Institutions face an existential paradox—adapt and rewrite their foundations, or collapse under the weight of their contradictions.

 4. The phase transition is inevitable—the only question is who recognizes it first.

 

The future is not uncertain. It is structured. The heist has already happened. The only question is: will you see it before the rest of the world does?
Limnocoris pusillus Montandon 1897
Creators: name: Moreira, Felipe Ferraz Figueiredo
name: Barbosa, Julianna Freires
name: Ribeiro, José Ricardo Inacio
name: Alecrim, Viviani Pereira
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Naucoridae
Limnocoris
Limnocoris pusillus

description: Limnocoris pusillus Montandon, 1897
Geographical distribution: Colombia, Brazil, Bolivia, and Argentina.
 Distribution in Brazil: Southeast and South regions (MG, RJ, SC, RS) (Montandon 1897; Nieser & Melo 1997; Nieser & López-Ruf 2001; Melo & Nieser 2004; Pelli et al. 2006; Souza et al. 2006; Ribeiro et al. 2010).
description: Published as part of Moreira, Felipe Ferraz Figueiredo, Barbosa, Julianna Freires, Ribeiro, José Ricardo Inacio & Alecrim, Viviani Pereira, 2011, Checklist and distribution of semiaquatic and aquatic Heteroptera (Gerromorpha and Nepomorpha) occurring in Brazil 2958, pp. 1-74 in Zootaxa 2958 (1) on page 46, DOI: 10.11646/zootaxa.2958.1.1, http://zenodo.org/record/5281851
Dynamic Monte Carlo Simulations for a Square-Lattice Ising Ferromagnet with a Phonon Heat Bath
Creators: name: Park, Kyungwha
name: Novotny, M. A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We derive a direct connection between Monte Carlo time and physical time in terms of physical parameters, using a quantum Hamiltonian with a $d$-dimensional phonon heat bath interacting with a square-lattice Ising ferromagnet. Based on the calculated transition rates, we perform dynamic Monte Carlo simulations using absorbing Markov chains to measure the lifetimes of the metastable state at low temperatures. We also calculate the lifetimes analytically using absorbing Markov chains. The phonon dynamic gives field-dependent prefactors in the lifetimes at low temperatures, that are different from the piecewise field-independent prefactors obtained from the Glauber dynamic.
description: 4 pages including 2 figures, submitted to the proceedings of CCP2001
Hippotulosas A-D: four new sesterterpenes from marine sponge Hippospongia fistulosa Lendenfeld, 1889
Creators: name: Hang, Dan Thuy
name: Trang, Do Thi
name: Bui Huu Tai
name: Pham Hai Yen
name: Thu, Vu Kim
name: Nguyen Xuan Nhiem
name: Van Kiem, Phan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry

description: Four new sesterterpenes, named as hippotulosas A-D (1–4), and a known sesterterpene furospinulosin-1 (5) were isolated from the marine sponge Hippospongia fistulosa by various chromatographic methods. Their structures were established by extensive spectroscopic analyses (IR, HR-ESI-MS, 1D and 2D NMR) and by comparison of the spectral data with those reported in the literature.
Anomalous X-ray pulsars and soft gamma-ray repeaters - the connection with supernova remnants
Creators: name: Gaensler, Bryan
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Many of the properties of anomalous X-ray pulsars (AXPs) and soft gamma-ray repeaters (SGRs) are still a matter of much debate, as is the connection (if any) between these two groups of sources. In cases where we can identify the supernova remnant (SNR) associated with an AXP or SGR, the extra information thus obtained can provide important constraints as to the nature of these exotic objects. In this paper, I explain the criteria by which an association between a SNR and an AXP/SGR should be judged, review the set of associations which result, and discuss the implications provided by these associations for the ages, environments and evolutionary pathways of the AXPs and SGRs. There are several convincing associations between AXPs and SNRs, demonstrating that AXPs are young neutron stars with moderate space velocities. The lack of associations between SGRs and SNRs implies that the SGRs either represent an older population of neutron stars than do the AXPs, or originate from more massive progenitors.
description: 10 pages, 3 embedded EPS figures, 3 JPG figures, uses cospar.sty. Invited review to appear in "High Energy Studies of Supernova Remnants and Neutron Stars" (COSPAR 2002), Advances in Space Research, in press. PS version with all figures embedded available at http://cfa-www.harvard.edu/~bgaensler/preprints/0212086.ps
title: Epidermicin NI01 and human β-defensin 2 as modulators of macrophage subset responses
Creators: name: Durante, Barbara
Publisher: name: University of Plymouth
Year: 2020
Subjects: subject: Antimicrobial peptides
subject: Macrophages
subject: M1
subject: M2
subject: TNF alpha
subject: PhD

description: Antimicrobial peptides (AMPs) and host defence peptides (HDPs) have been extensively investigated for their antimicrobial activity and evidence suggests that they can also modulate the host immune system. However, little is known about their effects on macrophages, a key cell population in inflammatory responses that mediates communication between innate and adaptive immunity. Macrophages are a pleiotropic cell population composed of different subsets that orchestrate diverse stages of inflammation with roles ranging from pro- to anti-inflammatory and thus, targets for immunomodulation in different diseases. Here, THP-1-derived M1- and M2-like cells (pro- and anti-inflammatory respectively) under stimulation of TLR4 by LPS were used as a model to investigate potential immunomodulatory effects of these peptides on macrophages. Human β-defensin 2 in the presence of the TLR4 agonist K12 LPS, up-regulated the release of the pro-inflammatory cytokines TNFα and IL-1β from M1- and M2-like macrophages. Conversely, epidermicin NI01 strongly up-regulated release of a number of pro-inflammatory cytokines in the presence and absence of K12 LPS in M1-like cells but only a subset of those in M2-like cells. Various inhibitors of pro-inflammatory cytokine release pathways allowed us to partially elucidate the mechanisms via which this happens. Regulation of macrophage function by these and other peptides may have clinical implications in a wide range of immune-related disorders, but there is much we do not yet understand about what role, if any, epidermicin may have in these processes. Human β-defensin 2-induced upregulation of TNFα and IL-1β from M2-like cells might be important in conditions driven by sustained M2 anti-inflammatory factors such as fibrosis.
Leading neutron production in $e^+p$ collisions at HERA
Creators: name: ZEUS Collaboration
name: Chekanov, S.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The production of neutrons carrying at least 20% of the proton beam energy ($\xl > 0.2$) in $e^+p$ collisions has been studied with the ZEUS detector at HERA for a wide range of $Q^2$, the photon virtuality, from photoproduction to deep inelastic scattering. The neutron-tagged cross section, $e p\to e' X n$, is measured relative to the inclusive cross section, $e p\to e' X$, thereby reducing the systematic uncertainties. For $\xl >$ 0.3, the rate of neutrons in photoproduction is about half of that measured in hadroproduction, which constitutes a clear breaking of factorisation. There is about a 20% rise in the neutron rate between photoproduction and deep inelastic scattering, which may be attributed to absorptive rescattering in the $γp$ system. For $0.64 < \xl < 0.82$, the rate of neutrons is almost independent of the Bjorken scaling variable $x$ and $Q^2$. However, at lower and higher $\xl$ values, there is a clear but weak dependence on these variables, thus demonstrating the breaking of limiting fragmentation. The neutron-tagged structure function, ${{F}^{\rm\tiny LN(3)}_2}(x,Q^2,\xl)$, rises at low values of $x$ in a way similar to that of the inclusive \ff of the proton. The total $γπ$ cross section and the structure function of the pion, $F^π_2(x_π,Q^2)$ where $x_π= x/(1-\xl)$, have been determined using a one-pion-exchange model, up to uncertainties in the normalisation due to the poorly understood pion flux. At fixed $Q^2$, $F^π_2$ has approximately the same $x$ dependence as $F_2$ of the proton.
description: 61 pages, 19 figures
Spin-Orbit Torque Devices for Hardware Security: From Deterministic to Probabilistic Regime
Creators: name: Patnaik, Satwik
name: Rangarajan, Nikhil
name: Knechtel, Johann
name: Sinanoglu, Ozgur
name: Rakheja, Shaloo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Emerging Technologies (cs.ET)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Protecting intellectual property (IP) has become a serious challenge for chip designers. Most countermeasures are tailored for CMOS integration and tend to incur excessive overheads, resulting from additional circuitry or device-level modifications. On the other hand, power density is a critical concern for sub-50 nm nodes, necessitating alternate design concepts. Although initially tailored for error-tolerant applications, imprecise computing has gained traction as a general-purpose design technique. Emerging devices are currently being explored to implement ultra-low-power circuits for inexact computing applications. In this paper, we quantify the security threats of imprecise computing using emerging devices. More specifically, we leverage the innate polymorphism and tunable stochastic behavior of spin-orbit torque (SOT) devices, particularly, the giant spin-Hall effect (GSHE) switch. We enable IP protection (by means of logic locking and camouflaging) simultaneously for deterministic and probabilistic computing, directly at the GSHE device level. We conduct a comprehensive security analysis using state-of-the-art Boolean satisfiability (SAT) attacks; this study demonstrates the superior resilience of our GSHE primitive when tailored for deterministic computing. We also demonstrate how probabilistic computing can thwart most, if not all, existing SAT attacks. Based on this finding, we propose an attack scheme called probabilistic SAT (PSAT) which can bypass the defense offered by logic locking and camouflaging for imprecise computing schemes. Further, we illustrate how careful application of our GSHE primitive can remain secure even on the application of the PSAT attack. Finally, we also discuss side-channel attacks and invasive monitoring, which are arguably even more concerning threats than SAT attacks.
description: To be published in IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Limnocoris rotundatus De Carlo 1951
Creators: name: Moreira, Felipe Ferraz Figueiredo
name: Barbosa, Julianna Freires
name: Ribeiro, José Ricardo Inacio
name: Alecrim, Viviani Pereira
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Naucoridae
Limnocoris
Limnocoris rotundatus

description: Limnocoris rotundatus De Carlo, 1951
Geographical distribution: Brazil.
Distribution in Brazil: South Region (PR) (Nieser & López-Ruf 2001).
description: Published as part of Moreira, Felipe Ferraz Figueiredo, Barbosa, Julianna Freires, Ribeiro, José Ricardo Inacio & Alecrim, Viviani Pereira, 2011, Checklist and distribution of semiaquatic and aquatic Heteroptera (Gerromorpha and Nepomorpha) occurring in Brazil 2958, pp. 1-74 in Zootaxa 2958 (1) on page 47, DOI: 10.11646/zootaxa.2958.1.1, http://zenodo.org/record/5281851
Additional file 2 of Mechanism of MyD88S mediated signal termination
Creators: name: Pustelny, Katarzyna
name: Kuska, Katarzyna
name: Gorecki, Andrzej
name: Musielak, Bogdan
name: Dobosz, Ewelina
name: Wladyka, Benedykt
name: Koziel, Joanna
name: Czarna, Anna
name: Holak, Tad
name: Dubin, Grzegorz
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1. Supplementary Figure S1. Myd88 ID is essential for nucleation of myddosome supramolecular organizing center (SMOC) in murine macrophage cell line RAW264.7. (A) Indicated mCherry labeled MyD88 variants (top) were overexpressed in RAW264.7 cells and imaged by confocal microscopy. Myddosome nucleation is indicated by arrowheads. (B) Plasmids overexpressing indicated MyD88 variants were transfected into RAW264.7 together with plasmids encoding NF-κB-responsive promoter driven luciferase reporter gene. Induction of reporter expression was monitored. Response was normalized to wild type MyD88L. Values are presented as means±SD from triplicate samples. Statistical significance was determined by Student’s t-test (*p<0.05, **p<0.001). Supplementary Table S1. Primers and constructs used in the study.
Charge transfer statistics and qubit dynamics at tunneling Fermi-edge singularity
Creators: name: Ponomarenko, V. V.
name: Larkin, I. A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Tunneling of spinless electrons from a single-channel emitter into an empty collector through an interacting resonant level of the quantum dot (QD) is studied, when all Coulomb screening of charge variations on the dot is realized by the emitter channel and the system is mapped onto an exactly solvable model of a dissipative qubit. In this model we describe the qubit density matrix evolution with a generalized Lindblad equation, which permit us to count the tunneling electrons and therefore relate the qubit dynamics to the charge transfer statistics. In particular, the coefficients of its generating function equal to the time dependent probabilities to have the fixed number of electrons tunneled into the collector are expressed through the parameters of a non-Hermitian Hamiltonian evolution of the qubit pure states in between the successive electron tunnelings. From the long time asymptotics of the generating function we calculate Fano factors of the second and third order (skewness) and establish their relation to the extra average and cumulant, respectively, of the charge accumulated in the transient process of the empty QD evolution beyond their linear time dependence. It explains the origin of the sub and super Poisson shot noise in this system and shows that the super Poisson signals existence of a non-monotonous oscillating transient current and the qubit coherent dynamics. The mechanism is illustrated with particular examples of the generating functions, one of which coincides in the large time limit with the $1/3$ fractional Poissonian realized without the real fractional charge tunneling.
description: 13 pages, 6 figures
Additional file 1 of Priority indicators for evaluating the impact of field epidemiology training programs – results of a global modified Delphi study
Creators: name: Flint, James A.
name: Housen, Tambri
name: Kirk, Martyn D.
name: Durrheim, David N.
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 1
Kinetic Theory and Hydrodynamics for a Low Density Gas
Creators: name: Dufty, James W.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Many features of real granular fluids under rapid flow are exhibited as well by a system of smooth hard spheres with inelastic collisions. For such a system, it is tempting to apply standard methods of kinetic theory and hydrodynamics to calculate properties of interest. The domain of validity for such methods is a priori uncertain due to the inelasticity, but recent systematic studies continue to support the utility of kinetic theory and hydrodynamics as both qualitative and quantitative descriptions for many physical states. The basis for kinetic theory and hydrodynamic descriptions is discussed briefly for the special case of a low density gas.
description: 10 pages; submitted to proceedings of ICTP Workshop "Challenges in Granular Matter"
MOESM1 of Infrared spectroscopy coupled to cloud-based data management as a tool to diagnose malaria: a pilot study in a malaria-endemic country
Creators: name: Heraud, Philip
name: Patutong Chatchawal
name: Molin Wongwattanakul
name: Patcharaporn Tippayawat
name: Doerig, Christian
name: Patcharee Jearanaikoon
name: Perez-Guaita, David
name: Bayden Wood
Publisher: name: figshare
Year: 2019
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 1: Text S1. STARD Checklist.
Average spectra of massive galaxies in the SDSS
Creators: name: Eisenstein, Daniel J.
name: Hogg, David W.
name: Fukugita, Masataka
name: Nakamura, Osamu
name: Bernardi, Mariangela
name: Finkbeiner, Douglas P.
name: Schlegel, David J.
name: Brinkmann, J.
name: Connolly, Andrew J.
name: Csabai, Istvan
name: Gunn, James E.
name: Ivezic, Zeljko
name: Lamb, Don Q.
name: Loveday, Jon
name: Munn, Jeffrey A.
name: Nichol, Robert C.
name: Schneider, Donald P.
name: Strauss, Michael A.
name: Szalay, Alex
name: York, Don G.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We combine Sloan Digital Sky Survey spectra of 22,000 luminous, red, bulge-dominated galaxies to get high S/N average spectra in the rest-frame optical and ultraviolet (2600A to 7000A). The average spectra of these massive, quiescent galaxies are early-type with weak emission lines and with absorption lines indicating an apparent excess of alpha elements over solar abundance ratios. We make average spectra of subsamples selected by luminosity, environment and redshift. The average spectra are remarkable in their similarity. What variations do exist in the average spectra as a function of luminosity and environment are found to form a nearly one-parameter family in spectrum space. We present a high signal-to-noise ratio spectrum of the variation. We measure the properties of the variation with a modified version of the Lick index system and compare to model spectra from stellar population syntheses. The variation may be a combination of age and chemical abundance differences, but the conservative conclusion is that the quality of the data considerably exceeds the current state of the models.
description: Astrophysical Journal, in press. 21 pages, LaTeX, 11 figures. Spectra available electronically from D. Eisenstein and eventually from ApJ
Gradient-free activation maximization for identifying effective stimuli
Creators: name: Xiao, Will
name: Kreiman, Gabriel
Publisher: name: arXiv
Year: 2019
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Biological sciences
subject: FOS: Computer and information sciences

description: A fundamental question for understanding brain function is what types of stimuli drive neurons to fire. In visual neuroscience, this question has also been posted as characterizing the receptive field of a neuron. The search for effective stimuli has traditionally been based on a combination of insights from previous studies, intuition, and luck. Recently, the same question has emerged in the study of units in convolutional neural networks (ConvNets), and together with this question a family of solutions were developed that are generally referred to as "feature visualization by activation maximization." We sought to bring in tools and techniques developed for studying ConvNets to the study of biological neural networks. However, one key difference that impedes direct translation of tools is that gradients can be obtained from ConvNets using backpropagation, but such gradients are not available from the brain. To circumvent this problem, we developed a method for gradient-free activation maximization by combining a generative neural network with a genetic algorithm. We termed this method XDream (EXtending DeepDream with real-time evolution for activation maximization), and we have shown that this method can reliably create strong stimuli for neurons in the macaque visual cortex (Ponce et al., 2019). In this paper, we describe extensive experiments characterizing the XDream method by using ConvNet units as in silico models of neurons. We show that XDream is applicable across network layers, architectures, and training sets; examine design choices in the algorithm; and provide practical guides for choosing hyperparameters in the algorithm. XDream is an efficient algorithm for uncovering neuronal tuning preferences in black-box networks using a vast and diverse stimulus space.
description: 16 pages, 8 figures, 3 tables
Sandwich-structured electrospun all-fluoropolymer membranes with thermal shut-down function and enhanced electrochemical performance
Creators: name: Wen, Rongyan
name: Gao, Zhihao
name: Luo, Lin
name: Cui, Xiaochen
name: Tang, Jie
name: Zheng, Zongmin
name: Zhang, Jianmin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biophysics
Biochemistry
Space Science
Medicine
Cell Biology
Neuroscience
Hematology

description: High safety and rate capability of lithium-ion batteries (LIBs) remain challenging. In this study, sandwich-structured poly(vinylidene fluoride)/poly(vinylidene fluoride-co-hexafluoropropylene)/poly(vinylidene fluoride) (PVDF/PVDF-HFP/PVDF) membranes with thermal shut-down function were successfully prepared through electrospinning. The effects of different weight ratios of PVDF and PVDF-HFP in a composite membrane on the physical and electrochemical properties of the membrane were explored. It was found that the composite membrane with 36 wt% PVDF-HFP (P/H2/P) showed excellent electrolyte absorption (367%) and ionic conductivity (2.5 × 10−3 S/cm). Half-cell with P/H2/P as separator exhibited higher discharge capacity and better cycle performance than commercial PP membrane. More importantly, thermally stable high melting-temperature PVDF was chosen as outer layer, while low melting-temperature PVDF-HFP was used as inner layer. Self-shutdown function of this separator was achieved when heated at 140 °C, providing a safety measure for LIBs. These results indicate that PVDF/PVDF-HFP/PVDF composite membrane is a promising separator candidate in high performance LIBs applications.
Beam Based Alignment of Interaction Region Magnets
Creators: name: Hoffstaetter, G. H.
name: Willeke, F.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: In conventional beam based alignment (BBA) procedures, the relative alignment of a quadrupole to a nearby beam position monitor is determined by finding a beam position in the quadrupole at which the closed orbit does not change when the quadrupole field is varied. The final focus magnets of the interaction regions (IR) of circular colliders often have some specialized properties that make it difficult to perform conventional beam based alignment procedures. At the HERA interaction points, for example, these properties are: (a) The quadrupoles are quite strong and long. Therefore a thin lens approximation is quite imprecise. (b) The effects of angular magnet offsets become significant. (c) The possibilities to steer the beam are limited as long as the alignment is not within specifications. (d) The beam orbit has design offsets and design angles with respect to the axis of the low-beta quadrupoles. (e) Often quadrupoles do not have a beam position monitor in their vicinity. Here we present a beam based alignment procedure that determines the relative offset of the closed orbit from a quadrupole center without requiring large orbit changes or monitors next to the quadrupole. Taking into account the alignment angle allows us to reduce the sensitivity to optical errors by one to two orders of magnitude. We also show how the BBA measurements of all IR quadrupoles can be used to determine the global position of the magnets. The sensitivity to errors of this method is evaluated and its applicability to HERA is shown.
INNOWACYJNOŚĆ WYBRANYCH ROLNICZYCH SPÓŁDZIELNI PRODUKCYJNYCH WOJEWÓDZTWA PODKARPACKIEGO
Creators: name: Górka, Małgorzata
name: Bober, Tomasz
name: Górka, Małgorzata
name: Bober, Tomasz
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: innovative activity
subject: innovations
subject: agricultural cooperatives

description: The study presents the innovative activity undertaken by agricultural cooperatives located in the Podkarpackie province. Researches showed that innovations implemented by the cooperatives mainly had the character of technological innovations, and in a small extent – non-technological character. When analyzing particular groups of cooperatives with different level of innovation, it was found that the most pro-development behaviors was observed in the I RSP group with a high level of innovation.
Limnocoris saphis Nieser & Lopez-Ruf 2001
Creators: name: Moreira, Felipe Ferraz Figueiredo
name: Barbosa, Julianna Freires
name: Ribeiro, José Ricardo Inacio
name: Alecrim, Viviani Pereira
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Naucoridae
Limnocoris
Limnocoris saphis

description: Limnocoris saphis Nieser & López-Ruf, 2001
Geographical distribution: Brazil.
 Distribution in Brazil: Southeast Region (MG) (Nieser & López-Ruf 2001; Pelli et al. 2006).
description: Published as part of Moreira, Felipe Ferraz Figueiredo, Barbosa, Julianna Freires, Ribeiro, José Ricardo Inacio & Alecrim, Viviani Pereira, 2011, Checklist and distribution of semiaquatic and aquatic Heteroptera (Gerromorpha and Nepomorpha) occurring in Brazil 2958, pp. 1-74 in Zootaxa 2958 (1) on page 47, DOI: 10.11646/zootaxa.2958.1.1, http://zenodo.org/record/5281851
Additional file 1 of Sodium butyrate attenuates microglia-mediated neuroinflammation by modulating the TLR4/MyD88/NF-κB pathway and microbiome-gut-brain axis in cardiac arrest mice
Creators: name: Sun, Jianfei
name: Lu, Liping
name: Lian, Yingtao
name: Xu, Song
name: Zhu, Ying
name: Wu, Yanping
name: Lin, Qianhui
name: Hou, Jing
name: Li, Yinping
name: Yu, Zhui
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 1.
A Study of the 't Hooft Model with the Overlap Dirac Operator
Creators: name: Berruto, F.
name: Giusti, L.
name: Hoelbling, C.
name: Rebbi, C.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present the results of an exploratory numerical study of two dimensional QCD with overlap fermions. We have performed extensive simulations for U(N_c) and SU(N_c) color groups with N_c=2, 3, 4 and coupling constants chosen to satisfy the 't Hooft condition g^2 N_c =const=4/3. We have computed the meson spectrum and decay constants, the topological susceptibility and the chiral condensate. For U(N_c) gauge groups, our results indicate that the Witten-Veneziano relation is satisfied within our statistical errors and that the chiral condensate for N_f=1 is compatible with a non-zero value. Our results exhibit universality in N_c and confirm once more the excellent chiral properties of the overlap-Dirac operator.
description: 18 pages, 4 figures
Scattering below the ground state for the 2$d$ radial nonlinear Schrödinger equation
Creators: name: Arora, Anudeep Kumar
name: Dodson, Benjamin
name: Murphy, Jason
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We revisit the problem of scattering below the ground state threshold for the mass-supercritical focusing nonlinear Schrödinger equation in two space dimensions. We present a simple new proof that treats the case of radial initial data. The key ingredient is a localized virial/Morawetz estimate; the radial assumption aids in controlling the error terms resulting from the spatial localization.
description: 11 pages
Electron correlation in the Si(100) surface
Creators: name: Paz, Oscar
name: da Silva, Antonio J. R.
name: Saenz, Juan Jose
name: Artacho, Emilio
Publisher: name: arXiv
Year: 2001
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Motivated by the controversy between quantum chemists and solid-state physicists, and by recent experimental results, spin-polarized density-functional (DFT) calculations are used to probe electron correlation in the Si(100) reconstructed surface. The ground state displays antiferromagnetic spin polarization for low dimer inclinations indicating, not magnetic order, but the importance of Mott-like correlations among dangling bonds. The lowest energy corresponds to a higher dimer inclination with no spin. DFT energies, however, should be taken with caution here. Our results together with quantum-chemical findings suggest dimers with highly correlated electrons that tend to buckle due to interactions with other dimers.
description: 5 pages, 1 eps figure, 1 table; RevTeX v3.1. To appear in Surface Science (proceedings of the European Conference On Surface Science, ECOSS-19, Madrid, Sept. 5-8, 2000)
Publishing aspects of the creation of children's books: a comparison of the editorial activity in a Malaysian and a British publishing house
Creators: name: Mahani, Che I.
Publisher: name: Loughborough University
Year: 2021
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Publishing aspects of the creation of children's books: a comparison of the editorial activity in a Malaysian and a British publishing house