cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Budget impact of ferric carboxymaltose treatment in patients with chronic heart failure and iron deficiency in Spain
Creators: name: Delgado, Juan F.
name: Oliva, Juan
name: González-Franco, Álvaro
name: Cepeda, Jose María
name: García-García, Jose Ángel
name: González-Domínguez, Almudena
name: Garcia-Casanovas, Albert
name: Merino, Silvia Jiménez
name: Comín-Colet, Josep
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: The treatment of iron deficiency (ID) with ferric carboxymaltose (FCM) improves the functional class and quality of life of chronic heart failure (CHF) patients with reduced left ventricular ejection fraction (LVEF), and reduces the rate of hospitalization due to worsening CHF. This study aims to evaluate the budget impact for the Spanish National Health System (SNHS) of treating ID in reduced LVEF CHF with FCM compared to non-iron treatment. We simulated a hypothetical cohort of 1000 CHF patients with ID and reduced LVEF based on the Spanish population characteristics. A decision-analytic model was also built using the data from the largest FCM clinical trial (CONFIRM-HF) that lasted for a year. We considered the use of healthcare resources from a national prospective study. A deterministic sensitivity analysis was carried out varying the corresponding baseline data by ±25%. The cost of treating the simulated population with FCM was €2,570,914, while that of the non‐iron treatment was €3,105,711, which corresponds to a cost saving of €534,797 per 1,000 patients in one year. Cost savings were mainly due to a decrease in the number of hospitalizations. All sensitivity analysis showed cost savings for the SNHS. FCM results in an annual cost saving of €534.80 per patient, and would thus be expected to reduce the economic burden of CHF in Spain.
Ab Initio Bethe-Salpeter Equation Approach to Neutral Excitations in Molecules with Numeric Atom-Centered Orbitals
Creators: name: Liu, Chi
name: Kloppenburg, Jan
name: Ren, Xinguo
name: Appel, Heiko
name: Kanai, Yosuke
name: Blum, Volker
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The Bethe-Salpeter equation (BSE) based on GW quasiparticle levels is a successful approach for calculating the optical gaps and spectra of solids and also for predicting the neutral excitations of small molecules. We here present an all-electron implementation of the GW+BSE formalism for molecules, using numeric atom-centered orbital (NAO) basis sets. We present benchmarks for low-lying excitation energies for a set of small organic molecules, denoted in the literature as "Thiel's set". Literature reference data based on Gaussian-type orbitals are reproduced to about one meV precision for the molecular benchmark set, when using the same GW quasiparticle energies and basis sets as the input to the BSE calculations. For valence correlation consistent NAO basis sets, as well as for standard NAO basis sets for ground state density-functional theory with extended augmentation functions, we demonstrate excellent convergence of the predicted low-lying excitations to the complete basis set limit. A simple and affordable augmented NAO basis set denoted "tier2+aug2" is recommended as a particularly efficient formulation for production calculations. We finally demonstrate that the same convergence properties also apply to linear-response time-dependent density functional theory within the NAO formalism.
MOESM1 of Tailored, psychological intervention for anxiety or depression in people with chronic obstructive pulmonary disease (COPD), TANDEM (Tailored intervention for ANxiety and DEpression Management in COPD): protocol for a randomised controlled trial
Creators: name: Sohanpal, Ratna
name: Pinnock, Hilary
name: Steed, Liz
name: Marshall, Karen Heslop
name: Chan, Claire
name: Kelly, Moira
name: Priebe, Stefan
name: C. Roberts
name: Singh, Sally
name: Smuk, Melanie
name: Saqi-Waseem, Sarah
name: Healey, Andy
name: Underwood, Martin
name: White, Patrick
name: Warburton, Chris
name: Taylor, Stephanie
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 Checklist: recommended items to address in a clinical trial protocol and related documents*.
5-Dimensional Chern-Simons Gauge Theory on an Interval: Massive Spin-2 Theory from Symmetry Breaking via Boundary Conditions
Creators: name: Torabian, Mahdi
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this note, we revisit the 4-dimensional theory of massive gravity through compactification of an extra dimension and geometric symmetry breaking. We dimensionally reduce the 5-dimensional topological Chern-Simons gauge theory of (anti) de Sitter group on an interval. We apply non-trivial boundary conditions at the endpoints to break all of the gauge symmetries. We identify different components of the gauge connection as invertible vierbein and spin-connection to interpret it as a gravitational theory. The effective field theory in four dimensions includes the dRGT potential terms and has a tower of Kaluza-Klein states without massless graviton in the spectrum. The UV cut of the theory is the Planck scale of the 5-dimensional gravity $l^{-1}$. If $ζ$ is the scale of symmetry breaking and $L$ is the length of the interval, then the masses of the lightest graviton $m$ and the level $n$ (for $n
description: 8 pages, published version
MOESM1 of Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs
Creators: name: Vargas-Caraveo, Alejandra
name: Sayd, Aline
name: Robledo-Montaña, Javier
name: Caso, Javier
name: Madrigal, José
name: García-Bueno, Borja
name: Leza, Juan
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1: Supplementary information.
Thyanta custator subsp. custator custator (Fabricius 1803
Creators: name: Rider, David A.
name: Swanson, Daniel R.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Thyanta
Thyanta custator
Thyanta custator custator (fabricius, 1803)

description: Thyanta custator custator (Fabricius, 1803)
 Distribution: United States: AL (Rider & Chapin 1992), FL, GA (Scott & Fiske 1902, Van Duzee 1917, Rider & Chapin 1992), LA, MS, NC, NH, NJ, NY, SC, TX, VA. (Bahamas, Hawaii)
 Comments: This form was listed in Froeschner (1988) under the name Thyanta custator. The records listed in Froeschner (1988) from Arkansas, Connecticut Delaware, Massachusetts, New Hampshire, Ohio, and Pennsylvania are based on misidentifications.
description: Published as part of Rider, David A. & Swanson, Daniel R., 2021, A distributional synopsis of the Pentatomidae (Heteroptera) north of Mexico, including new state and provincial records, pp. 1-69 in Zootaxa 5015 (1) on page 39, DOI: 10.11646/zootaxa.5015.1.1, http://zenodo.org/record/5159085
On the origin of the various types of radio emission in GRS 1915+105
Creators: name: Vadawale, S. V.
name: Rao, A. R.
name: Naik, S.
name: Yadav, J. S.
name: Ishwara-Chandra, C. H.
name: Rao, A. Pramesh
name: Pooley, G. G.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigate the association between the radio ``plateau'' states and the large superluminal flares in GRS 1915+105 and propose a qualitative scenario to explain this association. We identify several candidate superluminal flare events from available monitoring data on this source and analyze the contemporaneous RXTE pointed observations. We detect a strong correlation between the average X-ray flux during the ``plateau'' state and the total energy emitted in radio during the subsequent radio flare. We find that the sequence of events is similar for all large radio flares with a fast rise and exponential decay morphology. Based on these results, we propose a qualitative scenario in which the separating ejecta during the superluminal flares are observed due to the interaction of the matter blob ejected during the X-ray soft dips, with the steady jet already established during the ``plateau'' state. This picture can explain all types of radio emission observed from this source in terms of its X-ray emission characteristics.
description: Corrected typo in the author names, contents unchanged, accepted in ApJ
Cost-effectiveness of fingolimod versus interferon-β1a for the treatment of pediatric-onset multiple sclerosis in Canada
Creators: name: Nakhaipour, Hamid Reza
name: Umakanth Vudumula
name: Khurana, Vivek
name: Sébire, Guillaume
name: Mah, Jean K.
name: Pohl, Daniela
name: Schecter, Robyn
name: Adlard, Nicholas
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: To evaluate the cost-effectiveness of fingolimod versus interferon (IFN)-β1a at a dose of 30 μg per week for the treatment of relapsing pediatric-onset multiple sclerosis (POMS) in Canada. A discrete-time Markov model was developed to compare fingolimod with IFN β-1a over a time horizon of two years representing patients followed up to mean age of 18 years from a Canadian health care system perspective. Twenty-one health states based on the Expanded Disability Status Scale (EDSS) were considered: EDSS 0‒9 for relapsing multiple sclerosis (MS), EDSS 0‒9 for secondary progressive MS, and “Death.” Relative treatment efficacy for fingolimod versus IFN-β1a was estimated from the PARADIGMS study. Costs and resource use were obtained from published literature and Canadian sources. Utilities were estimated by mapping the Pediatric Quality of Life inventory data onto the Child Health Utility Index-9 Dimension using a published mapping algorithm. Future costs and benefits were discounted at 1.5% per annum. Compared with IFN β-1a, fingolimod led to an increase in quality-adjusted life-years (QALYs) (0.125) with incremental costs (Canadian dollars [CAD] 2,977) and to an incremental cost-effectiveness ratio (ICER) of CAD 23,886/QALY over a time horizon of two years representing patients followed up to mean age of 18 years. The monetary benefits of fingolimod treatment versus IFN β-1a at a willingness-to-pay (WTP) threshold of CAD 50,000 per QALY gained were higher than the costs. One-way sensitivity analysis and probabilistic sensitivity analysis (PSA) both confirmed the robustness of the results. The main limitations of this analysis primarily stem from the limited data availability in POMS. Fingolimod is cost effective compared with IFN β-1a for the treatment of POMS over a time horizon of two years representing patients followed up to a mean age of 18 years in Canada.
Two flavors of dynamical quarks on anisotropic lattices
Creators: name: PACS Collaboration
name: Umeda, T.
name: Aoki, S.
name: Fukugita, M.
name: Ishikawa, K-I.
name: Ishizuka, N.
name: Iwasaki, Y.
name: Kanaya, K.
name: Kuramashi, Y.
name: Lesk, V. I.
name: Namekawa, Y.
name: Okawa, M.
name: Taniguchi, Y.
name: Ukawa, A.
name: Yoshie, T.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We report on our study of two-flavor full QCD on anisotropic lattices using $O(a)$-improved Wilson quarks coupled with an RG-improved glue. The bare gauge and quark anisotropies corresponding to the renormalized anisotropy $ξ=a_s/a_t = 2$ are determined as functions of $β$ and $κ$, which covers the region of spatial lattice spacings $a_s\approx 0.28$--0.16 fm and $m_{PS}/m_V\approx 0.6$--0.9. The calibrations of the bare anisotropies are performed with the Wilson loop and the meson dispersion relation at 4 lattice cutoffs and 5--6 quark masses. Using the calibration results we calculate the meson mass spectrum and the Sommer scale $r_0$. We confirm that the values of $r_0$ calculated for the calibration using pseudo scalar and vector meson energy momentum dispersion relation coincide in the continuum limit within errors. This work serves to lay ground toward studies of heavy quark systems and thermodynamics of QCD including the extraction of the equation of state in the continuum limit using Wilson-type quark actions.
description: 16 pages, 23 figures, Version accepted for publication in Physical Review D
Assessment of Generative Adversarial Networks Model for Synthetic Optical Coherence Tomography Images of Retinal Disorders
Creators: name: Zheng, Ce
name: Xie, Xiaolin
name: Zhou, Kang
name: Chen, Bang
name: Chen, Jili
name: Ye, Haiyun
name: Li, Wen
name: Qiao, Tong
name: Gao, Shenghua
name: Yang, Jianlong
name: Liu, Jiang
Publisher: name: arXiv
Year: 2019
Subjects: subject: Medical Physics (physics.med-ph)
subject: Image and Video Processing (eess.IV)
subject: FOS: Physical sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Purpose: To assess whether a generative adversarial network (GAN) could synthesize realistic optical coherence tomography (OCT) images that satisfactorily serve as the educational images for retinal specialists and the training datasets for the classification of various retinal disorders using deep learning (DL). Methods: The GANs architecture was adopted to synthesis high-resolution OCT images training on a publicly available OCT dataset including urgent referrals (choroidal neovascularization and diabetic macular edema) and non-urgent referrals (normal and drusen). 400 real and synthetic OCT images were evaluated by 2 retinal specialists to assess image quality. We further trained 2 DL models on either real or synthetic datasets and compared the performance of urgent vs nonurgent referrals diagnosis tested on a local (1000 images from the public dataset) and clinical validation dataset (278 images from Shanghai Shibei Hospital). Results: The image quality of real vs synthetic OCT images was similar as assessed by 2 retinal specialists. The accuracy of discrimination as real vs synthetic OCT images was 59.50% for retinal specialist 1 and 53.67% for retinal specialist 2. For the local dataset, the DL model trained on real (DL_Model_R) and synthetic OCT images (DL_Model_S) had an area under the curve (AUC) of 0.99, and 0.98 respectively. For the clinical dataset, the AUC was 0.94 for DL_Model_R, 0.90 for DL_Model_S. Conclusions: The GAN-synthetic OCT images can be used by clinicians for educational purposes and developing DL algorithms. Translational Relevance: The medical image synthesis based on GANs is promising in human and machine to fulfill clinical tasks.
description: submitted
A cost-utility analysis of SIR-Spheres Y-90 resin microspheres versus best supportive care in the treatment of unresectable metastatic colorectal cancer refractory to chemotherapy in the UK
Creators: name: V. K. Brennan
name: F. Colaone
name: S. Shergill
name: R. F. Pollock
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Limited treatment options are available in chemotherapy-refractory or -intolerant metastatic colorectal cancer (mCRC). The objective of the present analysis was to evaluate the cost-utility of SIR-Spheres Y-90 resin microspheres relative to best supportive care (BSC) in the treatment of chemotherapy refractory mCRC from the perspective of the UK national healthcare payer. A cost-utility model was developed in Microsoft Excel to simulate transitions from progression-free survival to post-progression survival and death in patients with mCRC. Unit costs were captured in 2019 pounds sterling (GBP) based on the literature, formulary listings, and National Health Service (NHS) England reference costs. Future costs and effects were discounted at 3.5% per annum. A series of one-way sensitivity analyses, and probabilistic sensitivity analysis (PSA) were conducted. The base case analysis showed that SIR-Spheres Y-90 resin microspheres would result in an increase in discounted quality-adjusted life years gained from 0.69 quality-adjusted life years (QALYs) to 1.50 QALYs, with an associated increase in cost from GBP 15,268 to GBP 34,168 yielding an incremental cost-utility ratio of GBP 23,435 per QALY. PSA showed that there would be a 56% likelihood that SIR-Spheres Y-90 resin microspheres would be cost-effective relative to BSC at a willingness-to-pay threshold of GBP 30,000 per QALY gained. This cost-utility analysis showed that, relative to BSC, SIR-Spheres Y-90 resin microspheres would be a cost-effective treatment option for patients with mCRC in the UK setting from the national healthcare payer perspective.
Was Sie schon immer übers Crowdsourcen wissen wollten!
Creators: name: Graf, Nicole
Publisher: name: ETH Zurich
Year: 2019
Subjects: Crowdsourcing
Image Archive
Erschliessung

description: Um langfristig Crowdsourcing in Archiven und Bibliotheken mit Erfolg zu betreiben, gibt es wesentliche Faktoren, die beachtet werden sollten. Das Bildarchiv der ETH-Bibliothek betreibt seit rund 10 Jahren Crowdsourcing. Wir können also aus einem grossen Erfahrungswissen schöpfen: 1) Georeferenzierung & Metadatenmanagement; 2) Community-Aufbau & Community-Management; 3) Ressourcen, Aufwand – Ertrag.
Structure and diffusion in amorphous aluminium silicate: A molecular dynamics computer simulation
Creators: name: Winkler, Anke
name: Horbach, Jurgen
name: Kob, Walter
name: Binder, Kurt
Publisher: name: arXiv
Year: 2003
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The amorphous aluminium silicate (Al2O3)2(SiO2) [AS2] is investigated by means of large scale molecular dynamics computer simulations. We consider fully equilibrated melts in the temperature range 6100K >= T >= 2300K as well as glass configurations that were obtained from cooling runs from T=2300K to 300K with a cooling rate of about 10^12K/s. Already at temperatures as high as 4000K, most of the Al and Si atoms are four-fold coordinated by oxygen atoms. Thus, the structure of AS2 is that of a disordered tetrahedral network. The packing of AlO4 tetrahedra is very different from that of SiO4 tetrahedra in that Al is involved with a relatively high probability in small-membered rings and in triclusters in which an O atom is surrounded by four cations. We find as typical configurations two-membered rings with two Al atoms in which the shared O atoms form a tricluster. On larger length scales, the system shows a microphase separation in which the Al-rich network structure percolates through the SiO2 network. The latter structure gives rise to a prepeak in the static structure factor at a wavenumber q=0.5Å^{-1}. The comparison of experimental X-ray data with the results from the simulation shows a good agreement for the structure function. The diffusion dynamics in AS2 is found to be much faster than in SiO2. We show that the self-diffusion constants for O and Al are very similar and that they are by a factor of 2-3 larger than the one for Si.
description: 30 pages of Latex, 13 figures
Εκτίμηση κατακλίσεων για βαρέως πάσχοντες ασθενείς στη μονάδα εντατικής θεραπείας
Creators: name: Τσάμη, Ευανθία Αλέξανδρου
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Κατακλίσεις
Κλίμακα Cubbin/Jackson
Mονάδα Εντατικής Θεραπείας
Pressure ulcers
Cubbin/Jackson scale
Intensive Care Unit

description: Η πρόκληση των ελκών πίεσης (κατακλίσεις) αποτελεί σημαντική πρόκληση για τους επαγγελματίες της υγείας και επηρεάζει την ποιότητα της φροντίδας που παρέχεται. Συγκεκριμένα όσον αφορά τους νοσηλευτές, είναι αναγκαίο να γνωρίζουν τις τεχνικές που πρέπει να εφαρμόζονται ούτως ώστε να προλαμβάνονται οι κατακλίσεις και όταν εμφανιστούν πως να βελτιώσουν την κατάστασή τους. Η παρούσα μελέτη επιδιώκει να διερευνήσει τη σχέση των ενδογενών αιτιολογικών ή επιβαρυντικών παραγόντων με την εμφάνιση ελκών πίεσης σε ασθενείς πολυδύναμης Μονάδας Εντατικής Θεραπείας (ΜΕΘ). Για το σκοπό αυτό, εξετάστηκαν αναδρομικά οι φάκελοι νοσηλείας 20 ασθενών της ΜΕΘ του ΓΝΘ Παπανικολάου. Για την αξιολόγηση του κινδύνου εμφάνισης ελκών πίεσης καταγράφηκαν ενδογενείς παράγοντες που σχετίζονται με την εμφάνιση του φαινομένου και εφαρμόστηκε η σταθμισμένη κλίμακα Cubbin/Jackson. Για τους ασθενείς αυτούς, παρατηρήθηκαν κατακλίσεις τύπου I, τύπου II και τύπου Ⅲ κυρίως, ενώ τα αποτελέσματα έδειξαν ότι η γενική κατάσταση υγείας, ο σακχαρώδης διαβήτης και η καχεξία επιδρούν στην εμφάνιση ελκών πίεσης. Επιπλέον, προέκυψε θετική συσχέτιση μεταξύ του επιπέδου της κατάκλισης και της βαθμολογία στην κλίμακα Cubbin/Jackson, γεγονός το οποίο ενισχύει επιπλέον την αξιοπιστία της. Τα ευρήματα αυτά αναδεικνύουν το γεγονός ότι οι κατακλίσεις αποτελούν ένα φαινόμενο το οποίο χρειάζεται ιδιαίτερη φροντίδα και για το λόγο αυτό κρίνεται αναγκαία η κατάλληλη εκπαίδευση του νοσηλευτικού προσωπικού.
description: The occurrence of pressure ulcers (bedsores) is a significant challenge for healthcare professionals and affects the quality of care provided. Specifically with regard to nurses, it is necessary to know the techniques that must be applied in order to prevent bedsores and when they appear how to improve their situation. The present study seeks to investigate the relationship of endogenous causative or aggravating factors with the occurrence of pressure ulcers in multi-unit Intensive Care Unit (ICU) patients. For this purpose, the hospitalization files of 20 patients of the ICU of the Papanikolaou Hospital were retrospectively examined. To assess the risk of developing pressure ulcers, endogenous factors related to the occurrence of the phenomenon were recorded and the weighted Cubbin/Jackson scale was applied. For these patients, type 1, type 2and type 3 pressure ulcers were observed mostly, while the results showed that general health status, diabetes mellitus and cachexia influence the occurrence of pressure ulcers. In addition, a positive correlation was found between the level of recumbency and the Cubbin/Jackson - scale score, which further strengthens its reliability. These findings highlight the fact that bedsores are a phenomenon that needs special care and for this reason appropriate training of the nursing staff is deemed necessary.
Dynamics of a passive sliding particle on a randomly fluctuating surface
Creators: name: Gopalakrishnan, Manoj
Publisher: name: arXiv
Year: 2003
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the motion of a particle sliding under the action of an external field on a stochastically fluctuating one-dimensional Edwards-Wilkinson surface. Numerical simulations using the single-step model shows that the mean-square displacement of the sliding particle shows distinct dynamic scaling behavior, depending on whether the surface fluctuates faster or slower than the motion of the particle. When the surface fluctuations occur on a time scale much smaller than the particle motion, we find that the characteristic length scale shows anomalous diffusion with $ξ(t)\sim t^{2ϕ}$, where $ϕ\approx 0.67$ from numerical data. On the other hand, when the particle moves faster than the surface, its dynamics is controlled by the surface fluctuations and $ξ(t)\sim t^{1/2}$. A self-consistent approximation predicts that the anomalous diffusion exponent is $ϕ={2/3}$, in good agreement with simulation results. We also discuss the possibility of a slow cross-over towards asymptotic diffusive behavior. The probability distribution of the displacement has a Gaussian form in both the cases.
description: 6 pages, 4 figures, error in reference corrected and new reference added, submitted to Phys. Rev. E
title: When Images Remain
title: A Visual Polemic in 8 Acts
titleType: Subtitle
Creators: name: van Middelkoop, Catelijne
Publisher: name: The Dynamic Archive
Year: 2024
Subjects: Digital Media
Fine Arts

description: The burgeoning advancements in generative artificial intelligence and machine learning have cast a spotlight on the act of creation itself. Beyond the spoken word, images have emerged as potent catalysts for generating novel perspectives, transcending conventional boundaries of past interpretations, and reaffirming the significance of individual visual components. This component delves into the co-creation process of ‘When Images Remain. A Visual Polemic in 8 Acts’ (2023), an artwork that centers on the notion of ‘the space in between.’ In doing so, it challenges the conventional roles of text and images in the context of historical comprehension and future envisioning.
Thyanta maculata
Creators: name: Rider, David A.
name: Swanson, Daniel R.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Thyanta
Thyanta maculata

description: Thyanta maculata (Fabricius, 1775)
 Distribution: United States: TX. (Mexico, Central America)
 Comments: This species was listed under the name Thyanta casta Stål, a species that Rider & Chapin (1992) placed as a junior synonym of this species. Furthermore, Rider & Chapin (1992) determined that this species, in the United States, occurs only in Texas; records from Arizona, California, and New Mexico should be referred to Thyanta planifrons Ruckes, whereas those records from Florida should be transferred to Thyanta pseudocasta Blatchley. Rider & Chapin (1992) included this species in the subgenus Argosoma.
description: Published as part of Rider, David A. & Swanson, Daniel R., 2021, A distributional synopsis of the Pentatomidae (Heteroptera) north of Mexico, including new state and provincial records, pp. 1-69 in Zootaxa 5015 (1) on page 39, DOI: 10.11646/zootaxa.5015.1.1, http://zenodo.org/record/5159085
Serum microRNAs as a Diagnostic Biomarker for Early Detection of Breast Carcinoma
Creators: name: Saleem, Hadeeqa
name: Sufian, Shiza
name: Khan, Faisal
Publisher: name: Zenodo
Year: 2023

description: In 2020, there were 2.3 million women diagnosed with breast cancer and 685,000 deaths globally. This disparity reflects an unmet need, as breast cancer is often difficult to diagnose at early stages. Early diagnosis is essential for minimizing the mortality rate of breast cancer patients, which can be achieved through liquid biopsy. Liquid biopsy can be defined as a non-invasive method to detect tumor cells that have entered the bloodstream or formed metastatic deposits in blood, urine, feces, saliva, and other biological fluids. Liquid biopsy components include circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), exosomes, and circulating microRNAs.
title: Exploring the interrelationship between young adolescents’ online lives and school lives when transitioning from primary to secondary school in England
Creators: name: Madden, Janet
Publisher: name: The Open University
Year: 2025

description: Young adolescents face significant academic and social challenges during the transition from primary to secondary school, potentially impacting their sense of belonging and well-being. Concurrently, their increasing use of online spaces adds another layer of complexity to their experiences during this time. This study aims to provide further insight into these complexities by exploring the interrelationship of school and online spaces of young adolescents in England during their transition from primary to secondary school.

This research focuses on five young adolescents aged 10-11 years living in England at a time of transition, as it follows them from their final months in primary school into their secondary school. Based on a Communities of Practice framework, the data were collected and analysed using a sociocultural, interpretivist case-study methodology. The experiences and perceptions of the young adolescents were explored through collages, discussions, semi-structured interviews, focus group discussions, field notes and journal entries and analysed through thematic coding.

Findings, underpinned by an adapted Communities of Practice framework, suggest that these young adolescents used online spaces as a place of reassurance during transition. Friendships appeared to be of great importance at this time, and there seemed to be an entanglement of spaces where school and online communities of practice were sometimes accessed simultaneously. Findings also suggest that these young adolescents’ projected identities appeared similar across these spaces, although identity seemed to be a flexible construct in response to ongoing practice.

The study highlights social and cultural challenges that may be encountered during the transition from primary to secondary school in England, particularly those related to friendships and the complexities of managing them within and between school and online spaces. These findings prompt questions about the need to reconsider policies and practices governing the timing and approach to this critical time of transition.
Waiting for Clear Signals of New Physics in B and K Decays
Creators: name: Buras, Andrzej J.
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We classify the extensions of the Standard Model (SM) according to the structure of local operators in the weak effective Hamiltonian and the presence or absence of new flavour and CP-violating interactions beyond those represented by the CKM matrix. In particular we review characteristic properties of models with minimal flavour violation (MFV), models with significant contributions from Higgs penguins and models with enhanced Z^0 penguins carrying a large new CP-violating phase. Within the latter models, the anomalous behaviour of certain B\toπK observables implies large departures from the SM predictions for rare and CP-violating K and B decays. Most spectacular is the enhancement of Br(K_L->pi^0 nu nubar) by one order of magnitude and a strong violation of the MFV relation (\sin2β)_{πν\barν}=(\sin2β)_{ψK_S}. On the other hand our prediction for (\sin2β)_{ϕK_S}\approx 0.9 differs from the Belle result by the sign but is consistent with the BaBar value. We give a personal shopping list for the coming years.
description: Main latex-file, 4 figures, 22 pages
MOESM1 of Availability, accessibility and delivery to patients of the 28 orphan medicines approved by the European Medicine Agency for hereditary metabolic diseases in the MetabERN network
Creators: name: Jean-Michel Heard
name: Vrinten, Charlotte
name: Schlander, Michael
name: Bellettato, Cinzia
name: Lingen, Corine
name: Scarpa, Maurizio
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1: Table S1. Questionnaire addressed to MetabERN centres. Table S2. Responding centres. Table S3. List of the 28 EMA-approved OMPs for HMDs. Table S4. List of MetabERN centres and number of questionnaires completed
Supplementary document for Spatially-variant image deconvolution for photoacoustic tomography - 6448077.pdf
Creators: name: Xie, Dan
name: Wende, Dong
name: Zheng, Jiawei
name: Tian, Chao
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Supplemental Document
Macroscopic Brittleness: A Poorly Understood Initiation Mechanism for Extremely-Rapid, Flowlike Landslides in Fine Grained Colluvium
Creators: name: Aaron, Jordan
name: Loew, Simon
Publisher: name: ETH Zurich
Year: 2019

description: Geophysical Research Abstracts, 21
description: ISSN:1029-7006
description: ISSN:1607-7962
Testing Newton/GR, MoND and quantised inertia on wide binaries
Creators: name: McCulloch, M. E.
name: Lucio, J. H.
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Wide binary stars are within the low-acceleration regime in which galactic rotation curves deviate from Newtonian or general relativistic predictions. It has recently been observed that their rotation rates are similarly anomalous in a way that dark matter cannot explain, since it must be smooth on these small scales to fit galaxy rotation curves. Here, it is shown that Newtonian/GR models cannot predict these wide binaries since dark matter cannot be applied. It is also shown that MoND cannot predict these systems. However, a model which assumes that inertia is due to Unruh radiation made inhomogeneous in space by relativistic horizons (QI, quantised inertia) can predict these wide binaries, and it has the advantage of not needing an adjustable parameter.
description: 9 pages, 1 figure. Accepted by Astrophysics and Space Science on 26/7/2019
Early health economic modelling for a treatment candidate in hidradenitis suppurativa
Creators: name: Willems, Damon
name: Mata Charokopou
name: Evers, Silvia M. A. A.
name: Hiligsmann, Mickaël
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Hidradenitis suppurativa (HS) is a chronic skin condition causing inflammatory lesions, pain, scarring, and impaired mobility. Treatment options are limited and often lack success implying the need for additional/improved treatments. This research aimed to estimate the potential economic value of a treatment candidate, explore drivers of cost-effectiveness, and highlight economic evidence requirements for successful future value assessments. An early cost-effectiveness model was developed to assess the cost-effectiveness (cost per quality-adjusted life year (QALY) gained) of a treatment candidate compared against the only authorized biologic, adalimumab, for moderate to severe HS, from a UK National Health Service and Personal Social Service perspective. A targeted literature review of clinical and economic references and previous health technology assessments (HTA) was performed for development and validation of the early economic model used to present sensitivity analyses accompanying the base case cost-effectiveness results. Base case results revealed the candidate not to be cost-effective compared to adalimumab when considering a formal cost-effectiveness threshold of £30,000 per QALY gained. Scenario- and threshold analyses highlighted that reducing dosing or drug price by half improved the cost-effectiveness of the candidate. Cost-effectiveness was highly sensitive to health states’ utility values, treatment discontinuation, and resource utilization, in line with existing HTA evidence. The paucity of economic studies and uncertainties around the candidate presented methodological constraints that were addressed through sensitivity analyses. Key costs and health effects drivers were highlighted to contextualize under which circumstances a treatment candidate for moderate to severe HS would reach acceptable cost-effectiveness levels. This early economic evaluation suggested promising economic perspectives for treatment candidates in HS. Exploring novel ways to use clinical endpoints to simulate the patient pathway and clinically meaningful treatment achievements in future research will facilitate the value demonstration of candidates in disease areas with high unmet care need.
Efficient Synthesis of Linear Reversible Circuits
Creators: name: Patel, K. N.
name: Markov, I. L.
name: Hayes, J. P.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper we consider circuit synthesis for n-wire linear reversible circuits using the C-NOT gate library. These circuits are an important class of reversible circuits with applications to quantum computation. Previous algorithms, based on Gaussian elimination and LU-decomposition, yield circuits with O(n^2) gates in the worst-case. However, an information theoretic bound suggests that it may be possible to reduce this to as few as O(n^2/log n) gates. We present an algorithm that is optimal up to a multiplicative constant, as well as Theta(log n) times faster than previous methods. While our results are primarily asymptotic, simulation results show that even for relatively small n our algorithm is faster and yields more efficient circuits than the standard method. Generically our algorithm can be interpreted as a matrix decomposition algorithm, yielding an asymptotically efficient decomposition of a binary matrix into a product of elementary matrices.
description: 12 pages, 4 figures
The relation between momentum conservation and Newton's third law revisited
Creators: name: Diaz, Rodolfo A.
name: Herrera, William J.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Classical Physics (physics.class-ph)
subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Under certain conditions usually fulfilled in classical mechanics, the principle of conservation of linear momentum and Newton's third law are equivalent. However, the demonstration of this fact is usually incomplete in textbooks. We shall show here that to demonstrate the equivalence, we require the explicit use of the principle of superposition contained in Newton's second law. On the other hand, under some additional conditions the combined laws of conservation of linear and angular momentum, are equivalent to Newton's third law with central forces. The conditions for such equivalence apply in many scenarios of classical mechanics; once again the principle of superposition contained in Newton's second law is the clue.
description: 3 pages, no figures, format changed, minor typos corrected, abstract in English and Spanish. Version to appear in Revista Mexicana de Fisica
Thyanta perditor
Creators: name: Rider, David A.
name: Swanson, Daniel R.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Thyanta
Thyanta perditor

description: Thyanta perditor (Fabricius, 1794)
 Distribution: United States: AZ, FL, TX (Stål 1872, Rider & Chapin 1992). (Mexico, Central America, West Indies, South America).
 Comments: This species is characterized by having spinose humeral angles. There is also a form of Thyanta custator accerra (named spinosa by Ruckes 1957a) that has the humeral angles more or less spinose. Prior to the work of Ruckes (1957a), many workers referred to specimens with spinose humeral angles from the desert Southwest as this species. In truth, Rider & Chapin (1992) only listed two records of this species from the western United States: one from the very southern tip of Texas, and another in the southeastern corner of Arizona. All other records should be referred to Thyanta custator accerra.
description: Published as part of Rider, David A. & Swanson, Daniel R., 2021, A distributional synopsis of the Pentatomidae (Heteroptera) north of Mexico, including new state and provincial records, pp. 1-69 in Zootaxa 5015 (1) on page 39, DOI: 10.11646/zootaxa.5015.1.1, http://zenodo.org/record/5159085
Αλληλεπίδραση λίπανσης και μυκορριζικών μυκήτων στην πρόσληψη χαλκού και την ανάπτυξη της Tulipa australis
Creators: name: Τσινιπίζογλου, Νικόλαος Αβραάμ
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Tulipa australis
Λίπανση
Μυκορριζικοί μύκητες
Πρόσληψη χαλκού
Fertilization
Mychorizal fungi
Copper uptake

description: Η καλλιέργεια καλλωπιστικών φυτών, όπως οι τουλίπες, συχνά απαιτεί την χρήση λιπασμάτων ή και μυκορριζικών εμβολίων για την διασφάλιση της φυσιολογικής ανάπτυξης και την μεγιστοποίηση της ποιότητας των ανθέων. Στην παρούσα εργασία έγινε η διερεύνηση της αλληλεπίδρασης μυκορριζικού εμβολίου και λίπανσης στην θρέψη και ανάπτυξη του καλλωπιστικού φυτού Tulipa australis και ιδιαίτερα στην πρόσληψη χαλκού, σε πείραμα με φυτοδοχεία. Τα αποτελέσματα του πειράματος έδειξαν ότι τόσο τα μυκορριζικά εμβόλια διαφορετικής σύστασης (Rhzophagus intraradices και μίγμα μυκήτων από αμμοθίνες της Άνδρου), όσο και η μορφή των υγρών λιπασμάτων (μικτή οργανική και ανόργανη λίπανση) επηρέασαν με διαφορετικό τρόπο την ανάπτυξη και θρέψη των τουλιπών. Όσα φυτά εμβολιάστηκαν με τον μύκητα R. intraradices είχαν μεγαλύτερη υπόγεια βιομάζα, ενώ η ανόργανη λίπανση έδωσε τα μικρότερα φυτά. Η μικτή οργανική λίπανση δεν είχε καλυτέρα αποτελέσματα από τον μάρτυρα. Ο συνδυασμός ανόργανης λίπανσης με μυκορριζικά εμβόλια οδήγησε σε καλύτερη απορρόφηση θρεπτικών στοιχείων. Συγκεκριμένα, προσλήφθηκε μεγαλύτερη ποσότητα Na, Zn και Mn με το εμβόλιο R. Intraradices. Ωστόσο, η μεγαλύτερη βιοσσυσώρευση Cu μετρήθηκε στις μεταχειρίσεις χωρίς εμβολιασμό και λίπανση. Σύμφωνα με τα αποτελέσματα, γίνεται κατανοητό ότι ο εμβολιασμός με R. intraradices και η προσθήκη ανόργανου λιπάσματος αποτελούν τον καλύτερο συνδυασμό για την καλλιέργεια της Tulipa australis.
description: The cultivation of ornamental plants, such as tulips, often requires the use of fertilizers and/or mycorrhizal inoculants to ensure normal growth and the maximization of flower quality. In the present pot study, an investigation of the interaction of mycorrhizal inoculant and fertilization on the nutrition and growth of the ornamental plant Tulipa australis, particularly on Cu uptake, was carried out. The results of the experiment showed that both mycorrhizal inoculants of different compositions (Rhzophagus intraradices and an assemblage of fungi from sand dunes of Andros) and the form of liquid fertilizers (mixed organic and inorganic) affected differently the growth and nutrition of tulips. Plants inoculated with the fungus R. intraradices had higher root biomass, while inorganic fertilization yielded the smallest plants. The mixed organic fertilization performed no better than the control. The combination of inorganic fertilization and inoculation resulted in better nutrient uptake. Particularly, higher amounts of Na, Zn and Mn were taken up by the inoculum R. Intraradices. However, the highest Cu bioaccumulation was measured in the treatments without inoculation and fertilization. According to the results, it became evident that inoculation with R. intraradices and the addition of inorganic fertilizer is the best combination for the cultivation of Tulipa australis.
MOESM1 of Biological response and cytotoxicity induced by lipid nanocapsules
Creators: name: Szwed, Marzena
name: Torgersen, Maria
name: Remya Kumari
name: Yadava, Sunil
name: Pust, Sascha
name: Iversen, Tore
name: Skotland, Tore
name: Jyotsnendu Giri
name: Sandvig, Kirsten
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Additional file 1. Additional figures.
AC losses in type-II superconductors induced by nonuniform fluctuations of external magnetic field
Creators: name: Prigozhin, Leonid
name: Sokolovsky, Vladimir
Publisher: name: arXiv
Year: 2003
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Magnetic field fluctuations are inevitable in practical applications of superconductors and it is often necessary to estimate the AC losses these fluctuations induce. If the fluctuation wavelength is greater than the size of a superconductor, known estimates for an alternating uniform external magnetic field can be employed. Here we consider the opposite case and analyze, using a model critical-state problem, penetration of spatially nonuniform fluctuations into type-II superconductors. Numerical simulation is based on a variational formulation of the Bean model. The analytical solutions, found in a weak penetration limit, are used to evaluate AC losses for two types of fluctuations: the running and standing waves. It is shown that for spatially nonuniform fluctuations the losses are better characterized by the fluctuation penetration depth than by the fluctuation amplitude. The results can be used to estimate the AC losses in flywheels, electric motors, magnetic shields, etc.
description: 18 pages, 5 fugures
MOESM1 of Infection prevention practices in the Netherlands: results from a National Survey
Creators: name: Huis, Anita
name: Schouten, Jeroen
name: Lescure, Dominique
name: Krein, Sarah
name: Ratz, David
name: Saint, Sanjay
name: Hulscher, Marlies
name: M. Greene
Publisher: name: figshare
Year: 2020
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 1. TRIP Dutch questionnaire.
Two-dimensional layered materials for memristive and neuromorphic applications
Creators: name: Wang, Chen-Yu
name: Wang, Cong
name: Meng, Fanhao
name: Wang, Pengfei
name: Wang, Shuang
name: Liang, Shi-Jun
name: Miao, Feng
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: With many fantastic properties, memristive devices have been proposed as top candidate for next-generation memory and neuromorphic computing chips. Significant research progresses have been made in improving performance of individual memristive devices and in demonstrating functional applications based on small-scale memristive crossbar arrays. However, practical deployment of large-scale traditional metal oxides based memristive crossbar array has been challenging due to several issues, such as high-power consumption, poor device reliability, low integration density and so on. To solve these issues, new materials that possess superior properties are required. Two-dimensional (2D) layered materials exhibit many unique physical properties and show great promise in solving these challenges, further providing new opportunities to implement practical applications in neuromorphic computing. Here, recent research progress on 2D layered materials based memristive device applications is reviewed. We provide an overview of the progresses and challenges on how 2D layered materials are used to solve the issues of conventional memristive devices and to realize more complex functionalities in neuromorphic computing. Besides, we also provide an outlook on exploitation of unique properties of 2D layered materials and van der Waals heterostructures for developing new types of memristive devices and artificial neural mircrocircuits.
description: 38 pages,10 figures published in Advanced Electronic Materials
Flow characterization in fractured porous media using the temporo-ensemble PIV method
Creators: name: Ahkami, Mehrdad
name: Roesgen, Thomas
name: Saar, Martin O.
name: Kong, Xiangzhao
Publisher: name: ETH Zurich
Year: 2019

description: Geophysical Research Abstracts, 21
description: ISSN:1029-7006
description: ISSN:1607-7962