cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Molecular Aspects of Hepatitis C Virus Infection and Associated Mitochondrial DNA Damage
Creators: name: Rolfe, Kathryn Jane
Publisher: name: The Open University
Year: 2008

description: Hepatitis C virus (HCV) is the main cause of viral hepatitis in the UK and leads to chronic liver disease in many infected individuals. There is a substantial burden on diagnostic laboratories to provide rapid, cost-effective tests for monitoring HCV infection. Commercial assays are expensive and so the development of validated in-house methods is beneficial. This thesis describes the development and implementation of rapid and inexpensive real-time PCR assays for HCV quantitation and genotyping to support clinical practice. Additionally, the development of methods for defining HCV isolates at the subtype level, important in epidemiological and transmission studies, is described. These assays were utilised in a study on spontaneous HCV clearance, the results of which suggest that HCV type 1 infection and younger age at infection are factors which are associated with spontaneous viral clearance. Chronic HCV infection is linked to oxidative stress with numerous deleterious cellular effects. Mitochondrial DNA (mtDNA) is more susceptible to oxidative damage than nuclear DNA making it an ideal marker to assess the overall level of cellular DNA damage - including deletions and mutations. This thesis illustrates the development of real-time PCR assays to detect and quantify two major mtDNA deletions. The D-loop region of mtDNA is particularly prone to damage - with two well recognised 'hotspots of mutation'. The creation of an RSCA (heteroduplex-based) method using capillary electrophoresis, to detect and quantify damage in this region, is described. To evaluate the clinical utility of these assays, a study of mtDNA damage in patients with liver disease was undertaken. The aim of this study was to identify whether chronic HCV infection results in increased levels of mtDNA damage compared to other liver pathologies. Low levels of mtDNA deletions were detected in the majority of liver biopsy specimens and there was no correlation between liver aetiology and quantity of deletions. The RSCA method identified numerous D-loop mtDNA species within the liver tissue of several individuals. There was no correlation between liver aetiology and the presence of multiple D-loop species.
Simulating the recent star formation history in the halo of NGC 5128
Creators: name: Rejkuba, M.
name: Greggio, L.
name: Zoccali, M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Simulated color-magnitude diagrams (CMDs) are used to investigate the recent star formation history in NGC 5128. The comparison of the simulations with the observed UV CMD for a field in the NE shell, where recent star formation is present, constrains the initial mass function (IMF) and the duration of the star formation episode. The star formation burst is still on-going or at most has stopped some 2 Myr ago. The look-back time on the main sequence is set by the incompleteness of the U-band observations at V~26, and is of the order of 50 Myr. The post main sequence phases have a look-back time up to 100 Myr, setting the maximum observable time for the star formation in this field. The comparison of the observed and simulated luminosity functions and the number of post main sequence vs. total number of stars favours models with active star formation in the last 100 Myr. The data are best fitted by an IMF with Salpeter slope (α=2.35), and are also consistent with slopes in the range of 2
description: 16 pages, 10 figures; A&A in press
New compounds from Japanese oak wilt disease-associated fungus Raffaelea quercivora
Creators: name: Nakamura, Tomoki
name: Unang Supratman
name: Harneti, Desi
name: Maharani, Rani
name: Koseki, Takuya
name: Shiono, Yoshihito
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Two new compounds, a new lactone, quercilactone A (1), and (17R)-hydroxynafuredin (5), as well as five known compounds, scytalone (2), 3S,4R-hydoxy-scytalone (3), nafuredin (4), (+)-(3R,5R)-3-hydroxy-5-decanolide (6) and 3-ethyl-4-hydroxy-6-methyl-2H-pyran-2-one (7), were isolated from Raffaelea quercivora, a fungus that causes Japanese oak wilt disease. The structures of these compounds were determined by 1D and 2D NMR spectroscopic analyses. The absolute configuration at C-17 of 5 was determined to be R by the modified Mosher’s method. Compounds 1, 2, and 7 exhibited weak phytotoxic activity in lettuce seedlings at a concentration of 100 μg mL−1.
Isolate record for VAFB-ISO-853
Creators: name: Holloway, Corinne
Year: 1900
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: Chipped Stone
valueUri: https://core.tdar.org/browse/material-type/2/chipped-stone
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: This document is the isolated find record for VAFB-ISO-853. The artifact is a secondary flake.
title: Exploring Identity Change and Communities of Practice among Long Term Home Educating Parents
Creators: name: Safran, Leslie
Publisher: name: The Open University
Year: 2008

description: Home education, defined in this study as the full-time education of children in and around the home by their committed parents or guardians, is a growing educational option in both the US and the UK. It is a tremendous challenge for parents because it is a constantly lived intellectual and emotionally absorbing experience concerning the future of their children. Most research into home education focuses on children: this project explores it from the perspective of parents. Data was collected through fifty preliminary questionnaires and thirty-four in-depth interviews. Surprisingly, financial concerns, career curtailment and 'time for one's self' did not emerge as significant. However, parents had an enormous task to face, to think about styles and approaches to education. Being in a small minority group, moreover one that challenged established educational practice, also left parents feeling marginalised. The research describes how parents adapt to their new role and how this changes them as individuals. A theoretical framework which deals with changes both with regard to learning and identity is Wenger's (1998) Community of Practice which analyses learning through practice in a social setting and connects these practices to identity formation. The community of practice is defined according to its joint enterprise (common goal), mutual engagement (meeting up with others to pursue the common goal) and shared repertoire (memories, stories and jokes of the community). The theory was modified in order to apply it not only to the paradigmatic neighbourhood home education groups but also to virtual home education networks and even to the exceptional cases where parents relate through the home education constellation alone. It is further proposed that, without realising it, the experience of home educating is interwoven with broader self-development; parents do not only educate their children but themselves as well, including becoming more politically aware. They become different people, not only with regard to a radical change in their educational views but also experiencing a profound change of identity.
title: Alunos com multideficiência no ensino regular: acesso, participação e sucesso!?...
Creators: name: Pego, António
name: Nunes, Clarisse
Publisher: name: Escola Superior de Educação, Instituto Politécnico de Lisboa
Year: 2021

description: Este texto é um recorte do estudo empírico realizado no âmbito da dissertação de mestrado apresentada na Escola Superior de Educação de Lisboa para obtenção do grau de mestre em Educação Especial por parte do primeiro autor. A investigação analisa as práticas de inclusão desenvolvidas por professores no ensino regular, focando-se no acesso e na participação de alunos com Multideficiência (MD) em atividades conjuntas com colegas com Desenvolvimento Típico (DT). Portanto, procura-se compreender o modo como estes alunos estão a ser incluídos no Ensino Regular (ER) e como acedem ao currículo, nomeadamente quais os contextos e as atividades que lhes estão acessíveis.
On the Origin of the Globular Cluster FSR 1758
Creators: name: Yeh, Fu Chi
name: Carraro, Giovanni
name: Korchagin, Vladimir
name: Pianta, Camilla
name: Ortolani, Sergio
Publisher: name: arXiv
Year: 2020
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Globular clusters in the Milky Way are thought to have either an {\it in situ} origin, or to have been deposited in the Galaxy by past accretion events, like the spectacular Sagittarius dwarf galaxy merger. We aim to probe the origin of the recently discovered globular cluster FSR 1758, often associated with some past merger event, and which happens to be projected toward the Galactic bulge, by a detailed study of its Galactic orbit, and to assign it to the most suitable Galactic component. We employ three different analytical time-independent potential models to calculate the orbit of the cluster by using the Gauss Radau spacings integration method. In addition, a time-dependent bar potential model is added to account for the influence of the Galactic bar. We run a large suite of simulations to account for the uncertainties in the initial conditions, in a Montecarlo fashion. We confirm previous indications that the globular cluster FSR 1758 possesses a retrograde orbits with high eccentricity. The comparative analysis of the orbital parameters of star clusters in the Milky Way, in tandem with recent metallicity estimates, allows us to conclude that FSR1758 is indeed a Galactic bulge intruder. The cluster can therefore be considered an old metal poor halo globular cluster formed {\it in situ} and which is passing right now in the bulge region. Its properties, however, can be roughly accounted for also assuming that the cluster is part of some stream of extra-Galactic origin. We conclude that assessing the origin, either Galactic or extra-galactic, of globular clusters is surely a tantalising task. In any case, by using an {\it Occam's razor} argument, we tend to prefer an {\it in situ} origin for FSR 1758.
description: 8 pages, 3 figures, accepted for publication in Astronomy and Astrophysics
Angular Power Spectrum Estimation of Cosmic Ray Anisotropies with Full or Partial Sky Coverage
Creators: name: Deligny, O.
name: Armengaud, E.
name: Beau, T.
name: Da Silva, P.
name: Hamilton, J. -Ch.
name: Lachaud, C.
name: Letessier-Selvon, A.
name: Revenu, B.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We study the angular power spectrum estimate in order to search for large scale anisotropies in the arrival directions distribution of the highest-energy cosmic rays. We show that this estimate can be performed even in the case of partial sky coverage and validated over the full sky under the assumption that the observed fluctuations are statistically spatial stationary. If this hypothesis - which can be tested directly on the data - is not satisfied, it would prove, of course, that the cosmic ray sky is non isotropic but also that the power spectrum is not an appropriate tool to represent its anisotropies, whatever the sky coverage available. We apply the method to simulations of the Pierre Auger Observatory, reconstructing an input power spectrum with the Southern site only and with both Northern and Southern ones. Finally, we show the improvement that a full-sky observatory brings to test an isotropic distribution, and we discuss the sensitivity of the Pierre Auger Observatory to large scale anisotropies.
description: 16 pages, 6 figures, version accepted for publication by JCAP
Deliverable D3.1: Pilot Strategy
Creators: name: Fraunhofer Institute for Systems and Innovation Research
name: Friedewald, Michael
Publisher: name: Zenodo
Year: 2024

description: This deliverable presents an overview of the planning process for the TRANSCEND pilot activities, encompassing considerations on citizen involvement in technical research and development, an analysis of the fields where citizen engagement will be tested, and the initial steps towards implementation.

Chapter 1 defines our understanding of security technologies while emphasizing the importance of public engagement. It discusses the challenges and obstacles that have hindered progress in this field.

Chapter 2 introduces a stage-gate process for involving citizens in technology development. It explores how the principles of "Responsible Research and Innovation" can be translated into practical elements for engaging stakeholders and citizens. We basically address the questions of who should participate, what should be discussed and what methods should be used to do so.

Chapter 3 introduces four key fields of security research: Cybersecurity, Disaster Resilient Societies, Fight against Crime and Terrorism, and Border Management. It provides an overview of each field, examines potential problems and conflicts affecting citizens, and identifies key stakeholders that need to be involved in the engagement process.

Finally, Chapter 4 outlines the current plans for implementing citizen engagement through the pilot activities. It discusses the framework conditions and requirements for the pilots in each field. Additionally, it presents a concept of involving a network of cities to contribute real-life security projects and to mobilise citizens.
Soft modes in the easy plane pyrochlore antiferromagnet
Creators: name: Champion, J D M
name: Holdsworth, P C W
Publisher: name: arXiv
Year: 2003
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: Thermal fluctuations lift the high ground state degeneracy of the classical nearest neighbour pyrochlore antiferromagnet, with easy plane anisotropy, giving a first order phase transition to a long range ordered state. We show, from spin wave analysis and numerical simulation, that even below this transition a continuous manifold of states, of dimension N^{2/3} exist (N is the number of degrees of freedom). As the temperature goes to zero a further `order by disorder' selection is made from this manifold. The pyrochlore antiferromagnet Er_2Ti_2O_7, is believed to have an easy plane anisotropy and is reported to have the same magnetic structure. The latter is perhaps surprising, given that the dipole interaction lifts the degeneracy of the classical model in favour of a different structure. We interpret our results in the light of these facts.
description: 7 pages, 9 figures, to appear in JPCM - HFM2003 conference proceeding
Import price effects on retail prices in the US and abroad : two cases
Creators: name: Feinberg, Robert
Publisher: name: US International Trade Commission
Year: 2023
Subjects: classificationCode: 38
subject: Economics

description: I utilize the highly disaggregate EIU CityData and present some preliminary results looking at how retail prices of two goods almost exclusively imported, bananas and virgin olive oil, are affected by import prices of these goods; from another perspective, I consider how distributor margins respond to changes in import prices. To avoid dealing with the effects of within-destination-country distance on consumer prices, I consider only prices in cities at or near the port of entry. The findings of limited response are consistent with previous work and raise the issue of implications for welfare effects of trade and exchange rate policy. Given the combination of limited passthrough of import prices into final consumer prices and the likely low price elasticity for specific categories of groceries, the trade flow impacts of international shocks may be quite modest.
Zasoby a zrównoważony rozwój rolnictwa w Polsce po integracji z UE
Resources and Sustainable Development of Agriculture in Poland after Integration with the EU
Creators: name: Guth, Marta
name: Smędzik-Ambroży, Katarzyna
name: Guth, Marta
name: Smędzik-Ambroży, Katarzyna
Publisher: name: Unknown
Year: 2017
Subjects: subject: Agribusiness
subject: Environmental Economics and Policy
subject: Farm Management
subject: resources
subject: sustainable development
subject: individual farms
subject: Poland
subject: zasoby
subject: rozwój zrównoważony
subject: indywidualne gospodarstwo rolne

description: The study attempts to answer the question of whether there are differences in the economic and environmental sustainability of individual farms from areas which differ in conditions of resources for individual agriculture after Poland's integration with the EU. The research covered the years 2004-2014, individual FADN farms from each region in Poland, with special consideration of the Wielkopolska region. Research methodologies that were used include: the analysis of dynamics and structure; Ward method of agglomeration analysis by. It has been shown that in the clusters of regions which differ in agrarian structure, differences in economic and environmental sustainability for individual farms can also be found. / Synopsis. W opracowaniu podjęto próbę odpowiedzi na pytanie: czy na obszarach różniących się uwarunkowaniami zasobowym dla rozwoju rolnictwa indywidualnego, związanymi z tradycyjnymi czynnikami wytwórczymi, czyli ziemią, kapitałem i pracą, po integracji Polski z UE występowały różnice w zakresie zrównoważenia ekonomicznego i środowiskowego indywidualnych gospodarstw rolnych. Zakres czasowy analiz obejmował lata 2004-2014, podmiotowy dotyczył indywidualnych gospodarstw rolnych, prowadzących rachunkowość rolną FADN, nieprzerwanie w całym okresie badawczym (4224 gospodarstwa), zaś przestrzenny dotyczył poszczególnych województw w Polsce, ze szczególnym uwzględnieniem Wielkopolski. Zastosowano analizę dynamiki i struktury oraz aglomeracyjną analizę skupień metodą Warda z wykorzystaniem odległości euklidesowej. Udowodniono, że w indywidualnych gospodarstwach FADN z obszarów różniących strukturą agrarną rolnictwa indywidualnego, występowały różnice w zakresie zrównoważenia ekonomicznego i środowiskowego gospodarstw rolnych.
description: eISSN 2544-0659
Import price effects on retail prices in the US and abroad : two cases
Creators: name: Feinberg, Robert
Publisher: name: American University
Year: 2023

description: I utilize the highly disaggregate EIU CityData and present some preliminary results looking at how retail prices of two goods almost exclusively imported, bananas and virgin olive oil, are affected by import prices of these goods; from another perspective, I consider how distributor margins respond to changes in import prices. To avoid dealing with the effects of within-destination-country distance on consumer prices, I consider only prices in cities at or near the port of entry. The findings of limited response are consistent with previous work and raise the issue of implications for welfare effects of trade and exchange rate policy. Given the combination of limited passthrough of import prices into final consumer prices and the likely low price elasticity for specific categories of groceries, the trade flow impacts of international shocks may be quite modest.
Metadata aggregation: models and solutions
Creators: name: Leitão, Paulo
Publisher: name: Zenodo
Year: 2023
Subjects: ROSSIO Infrastructure, DARIAH-EU, Arts, Digital Humanities, Digital Research Infrastructures, Metadata aggregation, Models

description: Presentation by Paulo Leitão (FCG) at the International Workshop ROSSIO: "Building a Digital Research Infrastructure: ROSSIO Case Study" (16-17 fev.23), Organized by Amélia Aguiar Andrade, Daniel Alves & Helena Cabeleira (ROSSIO Infrastructure), held at NOVA-FCSH (Campus da Avenida de Berna, Auditório B3 - Torre B). This event was aimed at researchers, teachers, students and other specialists, agents, professionals and communities in the fields of Social Sciences, Humanities and Arts.
Supplementary material from Small burrowing amphipods cause major damage in a large kelp
Creators: name: Gutow, Lars
name: Poore, Alistair G. B.
name: Poblete, Manuel A. Díaz
name: Vieia Villalobos
name: Thiel, Martin
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Large herbivores such as sea urchins and fish consume a high proportion of benthic primary production and frequently control the biomass of marine macrophytes. By contrast, small mesograzers, including gastropods and peracarid crustaceans, are abundant on seaweeds but have low per capita feeding rates and their impacts on marine macrophytes are difficult to predict. To quantify how mesograzers can affect macrophytes, we examined feeding damage by the herbivorous amphipods Sunamphitoe lessoniophila and Bircenna sp., which construct burrows in the stipes of subtidal individuals of the kelp Lessonia berteroana in northern-central Chile, SE Pacific. Infested stipes showed a characteristic sequence of progressive tissue degeneration. The composition of the amphipod assemblages inside the burrows varied between the different stages of infestation of the burrows. Aggregations of grazers within burrows and microhabitat preference of the amphipods results in localized feeding, leading to stipe breakage and loss of substantial algal biomass. The estimated loss of biomass of single stipes varied between 1 and 77%. For the local kelp population, the amphipods caused an estimated loss of biomass of 24–44%. Consequently, small herbivores can cause considerable damage to large kelp species if their feeding activity is concentrated on structurally valuable algal tissue.
Next-Generation Information Technology Systems for Fast Detectors in Electron Microscop
Creators: name: Weber, Dieter
name: Clausen, Alexander
name: Dunin-Borkowski, Rafal E.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Performance (cs.PF)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The Gatan K2 IS direct electron detector (Gatan Inc., 2018), which was introduced in 2014, marked a watershed moment in the development of cameras for transmission electron microscopy (TEM) (Pan & Czarnik, 2016). Its pixel frequency, i.e. the number of data points (pixels) recorded per second, was two orders of magnitude higher than the fastest cameras available only five years before. Starting from 2009, the data rate of TEM cameras has outpaced the development of network, mass storage and memory bandwidth by almost two orders of magnitude. Consequently, solutions based on personal computers (PCs) that were adequate until then are no longer able to handle the resulting data rates. Instead, tailored high-performance setups are necessary. Similar developments have occurred for advanced X-ray sources such as the European XFEL, requiring special information technology (IT) systems for data handling (Sauter, Hattne, Grosse-Kunstleve, & Echols, 2013) (Fangohr, et al., 2018). Information and detector technology are currently under rapid development and involve disruptive technological innovations. This chapter briefly reviews the technological developments of the past 20 years, presents a snapshot of the current situation at the beginning of 2019 with many practical considerations, and looks forward to future developments.
Roadmap for the uptake of the Citizen Observatories' knowledge base
Creators: name: WeObserve Consortium
Publisher: name: Zenodo
Year: 2021
Subjects: Citizen Observatories, citizen science, roadmap

description: WeObserve brought together several Citizen Observatory projects to share and consolidate knowledge and identify best practices. Many of the insights gained have been synthesised into this detailed research and innovation roadmap for future Citizen Observatories, outlining focus areas, dedicated pathways and proposed actions in each of them. The aim of this roadmap is to outline a dynamic landscape and provide actionable pathways to further advance Citizen Observatories’ capabilities and impacts in the future. It is targeted at Citizen Observatory practitioners (research institutions, civil society organisations, public authorities and others) for conceptualising and directing key aspects of future Citizen Observatories; at national funding agencies of EU member states to identify potential scenarios for funding Citizen Observatories nationally; as well as for the European Commission as a consultation document for shaping Horizon Europe programme funding calls.
Isolate record for VAFB-ISO-825
Creators: name: Holloway, Corinne
Year: 1900
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: Chipped Stone
valueUri: https://core.tdar.org/browse/material-type/2/chipped-stone
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: This document is the isolated find record for VAFB-ISO-825. The artifact is a biface scraper.
Electronic Supplementary Material from Damselfishes alleviate the impacts of sediments on host corals
Creators: name: T. J. Chase
name: M. S. Pratchett
name: M. J. McWilliam
name: M. Y. Hein
name: S. B. Tebbett
name: M. O. Hoogenboom
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Figures and tables associated with sediment sampling and aquaria experiment
Diffuse Optical Light in Galaxy Clusters I: Abell 3888
Creators: name: Krick, J. E.
name: Bernstein, R. A.
name: Pimbblet, K. A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We are undertaking a program to measure the characteristics of the intracluster light (total flux, profile, color, and substructure) in a sample of 10 galaxy clusters with a range of cluster mass, morphology, and redshift. We present here the methods and results for the first cluster in that sample, A3888. We have identified an intracluster light (ICL) component in A3888 in V and r that contains 13\pm5% of the total cluster light and extends to 700h_{70}^{-1}kpc (~0.3 r_{200}) from the center of the cluster. The ICL color in our smallest radial bin is V-r = 0.3 \pm 0.1, similar to the central cluster ellipticals. The ICL is redder than the galaxies at 400 < r < 700h_{70}^{-1}kpc although the uncertainty in any one radial bin is high. Based on a comparison of V-r color with simple stellar models, the ICL contains a component which formed more than 7 Gyr ago (at z > 1), coupled with a high metallicity (1.0Z_{\odot} < Z_{ICL} \la 2.5Z_{\odot}), and a more centralized component which contains stars formed within the past 5 Gyr (at z ~ 1). The profile of the ICL can be roughly fit by a shallow exponential in the outer regions and a steeper exponential in the central region. We also find a concentration of diffuse light around a small group of galaxies 1.4h_{70}^{-1}Mpc from the center of the cluster. In addition, we find 3 low surface brightness features near the cluster center which are blue (V-r = 0.0) and contain a total flux of 0.1M*. Based on these observations and X-ray and galaxy morphology, we suggest that this cluster is entering a phase of significant merging of galaxy groups in the core, whereupon we expect the ICL fraction to grow significantly with the formation of a cD galaxy as well as the in-fall of groups.
description: 16 pages, 13 figures, 3 tables, AJ accepted
Identification of filamentary structures in the environment of superclusters of galaxies in the Local Universe
Creators: name: Santiago-Bautista, Iris
name: Caretta, Cesar A.
name: Bravo-Alfaro, Hector
name: Pointecouteau, Etienne
name: Andernach, Heinz
Publisher: name: arXiv
Year: 2020
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The characterization of the internal structure of the superclusters of galaxies (walls, filaments and knots where the clusters are located) is paramount for understanding the formation of the Large Scale Structure and for outlining the environment where galaxies evolved in the last Gyr. (i) To detect the compact regions of high relative density (clusters and rich groups of galaxies); (ii) to map the elongated structures of low relative density (filaments, bridges and tendrils of galaxies); (iii) to characterize the galaxy populations on filaments and study the environmental effects they are subject to. We employed optical galaxies with spectroscopic redshifts from the SDSS-DR13 inside rectangular boxes encompassing the volumes of a sample of 46 superclusters of galaxies, up to z=0.15. Our methodology implements different classical pattern recognition and machine learning techniques pipelined in the Galaxy Systems-Finding algorithm and the Galaxy Filaments-Finding algorithm. We detected in total 2,705 galaxy systems (clusters and groups, of which 159 are new) and 144 galaxy filaments in the 46 superclusters of galaxies. The filaments we detected have a density contrast above 3, with a mean value around 10, a radius of about 2.5 Mpc and lengths between 9 and 130 Mpc. Correlations between the galaxy properties (mass, morphology and activity) and the environment in which they reside (systems, filaments and the dispersed component) suggest that galaxies closer to the skeleton of the filaments are more massive by up to 25% compared to those in the dispersed component; 70 % of the galaxies in the filament region present early type morphologies and the fractions of active galaxies (both AGN and SF) seem to decrease as galaxies approach the filament. These results suggest that preprocessing in large scale filaments could have significant effects on galaxy evolution.
Maintaining new markets (Working Paper) : determinants of antitrust enforcement in Central and Eastern Europe
Creators: name: Feinberg, Robert
name: Meurs, Mieke
name: Reynolds, Kara
Publisher: name: American University (Washington, D.C.). Department of Economics
Year: 2023
Subjects: classificationCode: 38
subject: Economics

description: While others have examined the implementation and/or the stringency of enforcement of antitrust laws in post-socialist economies, this paper is the first study that attempts to explain the determinants of antitrust enforcement activity across post-socialist countries using economic and political variables. Using a panel of ten European post-socialist countries over periods ranging from 4 to 11 years, we find a number of significant determinants of enforcement in these countries. For example, larger economies engage in more antitrust enforcement, and countries have tended to increase their enforcement efforts over time. Our results also suggest that countries characterized by more unionization and less corruption tend to engage in greater antitrust enforcement of all types. Countries more successful in privatizing have filed fewer cases, while more affluent or developed countries investigate fewer cases of all types, consistent with an income-shifting motivation for antitrust.
Isolate record for VAFB-ISO-829
Creators: name: Holloway, Corinne
Year: 1900
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: Ground Stone
valueUri: https://core.tdar.org/browse/material-type/7/ground-stone
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: This document is the isolated find record for VAFB-ISO-829. The artifact is a bifacial mano.
Maintaining new markets (Working Paper) : determinants of antitrust enforcement in Central and Eastern Europe
Creators: name: Feinberg, Robert
name: Meurs, Mieke
name: Reynolds, Kara
Publisher: name: American University
Year: 2023

description: While others have examined the implementation and/or the stringency of enforcement of antitrust laws in post-socialist economies, this paper is the first study that attempts to explain the determinants of antitrust enforcement activity across post-socialist countries using economic and political variables. Using a panel of ten European post-socialist countries over periods ranging from 4 to 11 years, we find a number of significant determinants of enforcement in these countries. For example, larger economies engage in more antitrust enforcement, and countries have tended to increase their enforcement efforts over time. Our results also suggest that countries characterized by more unionization and less corruption tend to engage in greater antitrust enforcement of all types. Countries more successful in privatizing have filed fewer cases, while more affluent or developed countries investigate fewer cases of all types, consistent with an income-shifting motivation for antitrust.
On the deep minimum state in the Seyfert galaxy MCG-6-30-15
Creators: name: Reynolds, C. S.
name: Wilms, J.
name: Begelman, M. C.
name: Staubert, R.
name: Kendziorra, E.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: (abridged) We present a detailed spectral analysis of the first observation of the Seyfert 1 galaxy MCG-6-30-15 by the European Photon Imaging Camera on board the XMM-Newton observatory, together with contemporaneous data from the Proportional Counter Array on the Rossi X-ray Timing Explorer. Confirming our previously published result, we find that the presence of extremely broadened reflection features from an ionized relativistic accretion disk is required even when one employs the latest X-ray reflection models and includes the effect of complex absorption. The extremely broadened reflection features are also present if the primary continuum is modeled with a thermal Comptonisation spectrum rather than a simple power-law continuum. With this fact established, we examine these data using a relativistic smearing function corresponding to a ``generalized thin accretion disk'' model. We find strong evidence for torquing of the central parts of the accretion disk (presumably through magnetic interactions with the plunging region of the disk and/or the rotating black hole itself). We also perform a study of spectral variability within our observation. We find that the disk reflection features maintain roughly a constant equivalent width with respect to the observed continuum, as predicted by simple reflection models. Taken together with other studies of MCG-6-30-15 that find disk features to possess constant intensity at higher flux states, we suggest that the flux of disk features undergoes a saturation once the source emerges from a Deep Minimum state.
description: 16 pages, accepted for publication in MNRAS
title: Combination treatments in in vitro and in vivo models between molecules reverting epigenetic gene silencing and DNA-interacting anticancer drugs
Creators: name: Sabatino, Maria Antonietta
Publisher: name: The Open University
Year: 2008

description: Epigenetic transcriptional gene silencing plays a fundamental role in cancer development and has been considered as a target for cancer therapy in the last few years, mainly due to its reversibility by small molecules. Among the several methylated genes investigated, glutathione-S-transferase (GST) P1, a protein belonging to cellular detoxification systems, has been shown to be extensively promoter-methylated in prostate cancer. My study therefore describes a new therapeutic approach against prostate cancer, based on the combination of demethylating agents and brostallicin, a DNA minor groove binding drug, which is activated in the cell by binding to glutathione, a reaction catalyzed by GST.

Among the demethylating molecules tested on the prostatic cancer cell line LNCaP in in vitro combinations with brostallicin, zebularine was able to increase brostallicin activity with little toxicity compared to the other tested demethylating drugs.

These in vitro results prompted the in vivo testing of zebularine with brostallicin on LNCaP cells transplanted in mice. Prolonged treatment with zebularine was able to significantly improve brostallicin antitumour activity compared to both drugs administrated as single agents. When GSTP1 expression was investigated in treated samples versus untreated controls, no protein re-expression was found and this was related to the unchanged levels of GSTP1 promoter methylation. In contrast, the demethylating effect of zebularine was clearly evident in the promoter of GSTM1 gene, which is also silenced by methylation in LNCaP cells. GSTM1 codes for a class of GST enzymes that has recently been found to be more active on brostallicin than GSTP1.

This indicates that the activation of brostallicin cytotoxicity in LNCaP cells by zebularine likely depends on enzymatic activation by GSTM1 rather than GSTP1 and strengthens the feasibility of this combination as a treatment for prostate cancer in the clinic, and as model for the therapy of other solid tumours.
Open Access in Portugal: Landscape and future perspectives
Creators: name: Moreira, João Mendes
Publisher: name: Zenodo
Year: 2023
Subjects: ROSSIO Infrastructure, DARIAH-EU, Digital Research Infrastructures, Open Science, Open Access

description: Presentation by João Mendes Moreira (FCT/ FCCN) at the International Workshop ROSSIO: "Building a Digital Research Infrastructure: ROSSIO Case Study" (16-17 fev.23), Organized by Amélia Aguiar Andrade, Daniel Alves & Helena Cabeleira (ROSSIO Infrastructure), held at NOVA-FCSH (Campus da Avenida de Berna, Auditório B3 - Torre B). This event was aimed at researchers, teachers, students and other specialists, agents, professionals and communities in the fields of Social Sciences, Humanities and Arts.
PICRUSt analysis from Honeybee microbiome is stabilized in the presence of propolis
Creators: name: Perot Saelao
name: Borba, Renata S.
name: Ricigliano, Vincent
name: Spivak, Marla
name: Simone-Finstrom, Michael
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 60114 Systems Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Description of PICRUSt analysis methods and discussion of the results
Universal corrections to the Fermi-liquid theory
Creators: name: Chubukov, A. V.
name: Maslov, D. L.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We show that the singularities in the dynamical bosonic response functions of a generic 2D Fermi liquid give rise to universal, non-analytic corrections to the Fermi-liquid theory. These corrections yield a $T^2$ term in the specific heat, $T$ terms in the effective mass and the uniform spin susceptibility $χ_s (Q=0,T)$, and $|Q|$ term in $χ_s (Q,T=0)$. The existence of these terms has been the subject of recent controversy, which is resolved in this paper. We present exact expressions for all non-analytic terms to second order in a generic interaction $U(q)$ and show that only U(0) and $U(2p_F)$ matter.
description: references added, a typo corrected
Tetragonal superstructure of the antiskyrmion hosting Heusler compound Mn1.4PtSn
Creators: name: Vir, Praveen
name: Kumar, Nitesh
name: Borrmann, Horst
name: Jamijansuren, Bayardulam
name: Kreiner, Guido
name: Shekhar, Chandra
name: Felser, Claudia
Publisher: name: arXiv
Year: 2020
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Skyrmions in non-centrosymmetric magnets are vortex-like spin arrangements, viewed as potential candidates for information storage devices. The crystal structure and non-collinear magnetic structure together with magnetic and spin-orbit interactions define the symmetry of the Skyrmion structure. We outline the importance of these parameters in the Heusler compound Mn1.4PtSn which hosts antiskyrmions, a vortex-like spin texture related to skyrmions.1 We overcome the challenge of growing large micro-twin-free single crystals of Mn1.4PtSn which has proved to be the bottleneck for realizing bulk skyrmionic/antiskyrmionic states in a compound. The use of 5d-transition metal, platinum, together with manganese as constituents in the Heusler compound such as Mn1.4PtSn is a precondition for the non-collinear magnetic structure. Due to the tetragonal inverse Heusler structure, Mn1.4PtSn exhibits large magneto-crystalline anisotropy and D2d symmetry, which are necessary for antiskyrmions. The superstructure in Mn1.4PtSn is induced by Mn-vacancies which enables a ferromagnetic exchange interaction to occur. Mn1.4PtSn, the first known tetragonal Heusler superstructure compound, opens up a new research direction for properties related to the superstructure in a family containing thousands of compounds.
description: Includes 4 Figures and Supplementary information
title: Morel-Lavallée lesion - a reminder of a small piece in the trauma puzzle
Creators: name: rotariu, gabriela
Publisher: name: EURORAD
Year: 2021
Subjects: subject: Musculoskeletal system
subject: Musculoskeletal soft tissue
subject: Trauma
subject: CT
subject: MR
subject: Ultrasound
subject: Clinical Cases

description: Clinical History: A 44-year old patient was referred to the radiology department to undergo a thoracic, abdominal, and pelvic CT scan after suffering a fall from height (~ 2 meters). The CT scan revealed a soft-tissue lesion located superficially at the right upper thigh area, which was furthermore investigated by ultrasound and MRI.

description: 44 years, male
An Anisotropic Ballistic Deposition Model with Links to the Ulam Problem and the Tracy-Widom Distribution
Creators: name: Majumdar, Satya N.
name: Nechaev, Sergei
Publisher: name: arXiv
Year: 2003
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We compute exactly the asymptotic distribution of scaled height in a (1+1)--dimensional anisotropic ballistic deposition model by mapping it to the Ulam problem of finding the longest nondecreasing subsequence in a random sequence of integers. Using the known results for the Ulam problem, we show that the scaled height in our model has the Tracy-Widom distribution appearing in the theory of random matrices near the edges of the spectrum. Our result supports the hypothesis that various growth models in $(1+1)$ dimensions that belong to the Kardar-Parisi-Zhang universality class perhaps all share the same universal Tracy-Widom distribution for the suitably scaled height variables.
description: 5 pages Revtex, 3 .eps figures included, new references added
On the peculiar torque reversals and the X-ray luminosity history of the accretion-powered X-ray pulsar 4U 1626--67
Creators: name: Benli, Onur
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We have investigated the rotational and the X-ray luminosity ($L_{\mathrm{x}}$) observations of 4U 1626--67 accumulated during the last four decades. It has been recorded that the source underwent a torque reversal twice. We have tried to understand whether this eccentrical sign-switch of the period derivative ($\dot{P}$) of the source could be accounted for with the existing torque models. We have found that the observed source properties are better estimated with the distances close to the lower limit of the previously predicted distance range ($5-13$ kpc). Furthermore, assuming an inclined rotator, we have considered the partial accretion/ejection from the co-rotation radius that leads different $L_{\mathrm{x}}$-$\dot{P}$ profiles than the aligned rotator cases. We have concluded that the oblique rotator assumption brings at least equally best fitting to the observed X-ray luminosity and the rotational properties of 4U 1626--67. More importantly, the estimated change of the mass accretion rate which causes the change in observed $L_{\mathrm{x}}$ of 4U 1626--67 is much less than that is found in an aligned rotator case. In other words, without the need for a substantial modification of mass accretion rate from the companion star, the range of the observed X-ray luminosity could be explained naturally with an inclined magnetic axis and rotation axis of the neutron star.
description: Submitted to MNRAS. Comments are welcome!
Quantum phase transitions of magnetic rotons
Creators: name: Schmalian, Joerg
name: Turlakov, Misha
name: ;
Publisher: name: arXiv
Year: 2003
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Due to weak spin-orbit coupling, the magnetic excitations of an itinerant ferromagnet become magnetic rotons, excitations with degenerate minima on a hypersphere at finite wavevector. Using self-consistent Hartree and renormalization group calculations, we study weak fluctuation-driven first-order quantum phase transitions, a quantum tricritical point controlled by anisotropy and the non-Fermi liquid behavior associated with the large phase volume of magnetic rotons. We propose that magnetic rotons are essential for the description of the anomalous high-pressure behavior of the itinerant helical ferromagnet MnSi.
description: 5 pages, 2 figures, revised version