title: ÐÐ½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½ÑÐµ Ð¿ÐµÐ¿ÑÐ¸Ð´Ñ ÐºÐ°Ðº Ð¿ÑÐ¾ÑÐ¾ÑÐ¸Ð¿Ñ Ð½Ð¾Ð²ÑÑ Ð°Ð½ÑÐ¸Ð±Ð¸Ð¾ÑÐ¸ÐºÐ¾Ð²
title: ÑÐ±Ð¾ÑÐ½Ð¸Ðº Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð¾Ð² Ð¼Ð¸Ð½Ð¸-ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ð¸ Ñ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¼ ÑÑÐ°ÑÑÐ¸ÐµÐ¼, 18â19 Ð¸ÑÐ»Ñ 2024 Ð³Ð¾Ð´Ð°, Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³
titleType: Subtitle
title: Antimicrobial Peptides as Prototypes of Novel Antibiotics
Creators: name: "ÐÐ½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½ÑÐµ Ð¿ÐµÐ¿ÑÐ¸Ð´Ñ ÐºÐ°Ðº Ð¿ÑÐ¾ÑÐ¾ÑÐ¸Ð¿Ñ Ð½Ð¾Ð²ÑÑ  Ð°Ð½ÑÐ¸Ð±Ð¸Ð¾ÑÐ¸ÐºÐ¾Ð²", Ð¼Ð¸Ð½Ð¸-ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ñ Ñ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¼ ÑÑÐ°ÑÑÐ¸ÐµÐ¼
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2024
Subjects: ÐÐ½ÑÐ¸Ð±Ð¸Ð¾ÑÐ¸ÐºÐ¸

description: Ð§ÐµÑÐ²ÐµÑÑÐ°Ñ Ð¼Ð¸Ð½Ð¸-ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ñ Ñ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¼ ÑÑÐ°ÑÑÐ¸ÐµÐ¼ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑÑ Ð² ÑÐ°Ð¼ÐºÐ°Ñ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¿ÑÐ¾ÐµÐºÑÐ° Â«ÐÐ½ÑÐµÐºÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð±Ð¾Ð»ÐµÐ·Ð½Ð¸ Ð¸ Ð°Ð½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½Ð°Ñ ÑÐµÑÐ°Ð¿Ð¸ÑÂ» Ð² ÐÐ°ÑÑÐ½Ð¾Ð¼ ÑÐµÐ½ÑÑÐµ Ð¼Ð¸ÑÐ¾Ð²Ð¾Ð³Ð¾ ÑÑÐ¾Ð²Ð½Ñ Â«Ð¦ÐµÐ½ÑÑ Ð¿ÐµÑÑÐ¾Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ Ð¼ÐµÐ´Ð¸ÑÐ¸Ð½ÑÂ» (Ð¿ÑÐ¸ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²Ð¾Ð¹ Ð¿Ð¾Ð´Ð´ÐµÑÐ¶ÐºÐµ ÐÐ¸Ð½Ð¸ÑÑÐµÑÑÑÐ²Ð° Ð½Ð°ÑÐºÐ¸ Ð¸ Ð²ÑÑÑÐµÐ³Ð¾ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð Ð¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð¤ÐµÐ´ÐµÑÐ°ÑÐ¸Ð¸, Ð¡Ð¾Ð³Ð»Ð°ÑÐµÐ½Ð¸Ðµ â 075-15-2022-302 Ð¾Ñ 20.04.2022 Ð³.). ÐÐ¸Ð½Ð¸-ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ñ Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ð°Ð¼ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð½Ð¾Ð²ÑÑ Ð°Ð½ÑÐ¸Ð±Ð¸Ð¾ÑÐ¸ÐºÐ¾Ð² Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð°Ð½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½ÑÑ Ð¿ÐµÐ¿ÑÐ¸Ð´Ð¾Ð² (ÐÐÐ) ÐºÐ°Ðº ÑÑÐµÐ´ÑÑÐ² Ð±Ð¾ÑÑÐ±Ñ Ñ Ð±Ð°ÐºÑÐµÑÐ¸ÑÐ¼Ð¸ Ñ Ð¼Ð½Ð¾Ð¶ÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ Ð»ÐµÐºÐ°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÑÑ, Ð²ÑÐ·ÑÐ²Ð°ÑÑÐ¸Ð¼Ð¸ Ð±Ð¾Ð»ÑÐ½Ð¸ÑÐ½ÑÐµ Ð¸Ð½ÑÐµÐºÑÐ¸Ð¸, Ð²ÐºÐ»ÑÑÐ°Ñ Ð²Ð¾Ð·Ð½Ð¸ÐºÐ°ÑÑÐ¸Ðµ Ð² ÑÐµÑÐµÐ½Ð¸Ðµ Ð¸Ð»Ð¸ Ð¿Ð¾ÑÐ»Ðµ COVIDâ19. ÐÑÐ´ÑÑ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ ÑÑÑÑÐºÑÑÑÐ½ÑÐµ ÐºÐ»Ð°ÑÑÑ ÐÐÐ ÐºÐ°Ðº Ð¼Ð°ÑÑÐ¸ÑÑ Ð´Ð»Ñ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð½Ð¾Ð²ÑÑ ÑÑÑÐµÐºÑÐ¸Ð²Ð½ÑÑ Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ¾Ð² (Î±-ÑÐ¿Ð¸ÑÐ°Ð»ÑÐ½ÑÐµ, Î²-ÑÑÑÑÐºÑÑÑÐ½ÑÐµ, Ð¿ÑÐ¾Ð»Ð¸Ð½-Ð±Ð¾Ð³Ð°ÑÑÐµ Ð¿ÐµÐ¿ÑÐ¸Ð´Ñ), Ð¾Ð±ÑÑÐ¶Ð´ÐµÐ½Ñ Â«Ð·Ð°Â» Ð¸ Â«Ð¿ÑÐ¾ÑÐ¸Ð²Â» ÑÑÐ¸Ñ Ð²ÐµÑÐµÑÑÐ². Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ ÐÐÐ Ð² ÐºÐ¾Ð¼Ð±Ð¸Ð½Ð°ÑÐ¸Ð¸ Ñ ÐºÐ¾Ð½Ð²ÐµÐ½ÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÐ¼Ð¸ Ð°Ð½ÑÐ¸Ð±Ð¸Ð¾ÑÐ¸ÐºÐ°Ð¼Ð¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ñ Ð½Ð°Ð½Ð¾ÑÐ°ÑÑÐ¸ÑÐ°Ð¼Ð¸ Ð¼ÐµÑÐ°Ð»Ð»Ð¾Ð². ÐÐ±ÑÑÐ¶Ð´ÐµÐ½Ñ Ð´ÑÑÐ³Ð¸Ðµ ÑÐ¸Ð¿Ñ Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÐÐÐ: Ð¸Ð¼Ð¼ÑÐ½Ð¾Ð¼Ð¾Ð´ÑÐ»Ð¸ÑÑÑÑÐ¸Ðµ, Ð¿ÑÐ¾ÑÐ¸Ð²Ð¾Ð¾Ð¿ÑÑÐ¾Ð»ÐµÐ²ÑÐµ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð°, Ð²Ð·Ð°Ð¸Ð¼Ð¾Ð´ÐµÐ¹ÑÑÐ²Ð¸Ðµ ÐÐÐ Ñ ÑÐ¸ÑÑÐµÐ¼Ð¾Ð¹ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐ¼ÐµÐ½ÑÐ°. ÐÐ»Ð°Ð²Ð½Ð°Ñ Ð·Ð°Ð´Ð°ÑÐ° Ð¼Ð¸Ð½Ð¸-ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ð¸ â Ð¿Ð¾Ð¸ÑÐº Ð½Ð¾Ð²ÑÑ Ð¿ÑÑÐµÐ¹ Ð½Ð°ÑÑÐ½Ð¾Ð³Ð¾ ÑÐ¾ÑÑÑÐ´Ð½Ð¸ÑÐµÑÑÐ²Ð°. ÐÐ¸Ð½Ð¸-ÐºÐ¾Ð½ÑÐµÑÐµÐ½ÑÐ¸Ñ Ð¿ÑÐ¸ÑÑÐ¾ÑÐµÐ½Ð° Ðº 300-Ð»ÐµÑÐ¸Ñ Ð Ð¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð¹ Ð°ÐºÐ°Ð´ÐµÐ¼Ð¸Ð¸ Ð½Ð°ÑÐº.
description: The IV Mini-Ð¡onference with International Participation is holding in the frame of realization of the project âInfectious diseases and antimicrobial therapyâ at the World-Class Research Centre for Personalized Medicine (with the financial support of the Ministry of Science and Higher Education of the Russian Federation, Agreement â 075-15-2022-302). The Mini-Ð¡onference is devoted to the prospects of developing novel antibiotics on the base of antimicrobial peptides (AMPs) as tools for combating multidrug resistant bacteria causing severe hospital infections including those arising during or after COVIDâ19. Varied structural classes of AMPs will be considered as templates for creation of such potent drugs (Î±-helical, Î²-hairpin, proline-rich peptides), the pros and cons of these substances will be discussed. An application of AMPs in combination with conventional antibiotics as well as with metal nanoparticles also will be under consideration. Other types of the biological activity of AMPs will be discussed: immunomodulatory, anti-tumor activities, interaction of AMPs with the complement system. The main aim of the Mini-Conference is finding new ways for scientific collaboration. The Mini-Ð¡onference is dedicated to the 300th anniversary of the Russian Academy of Sciences.