cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Homocysteine-Lowering Treatment and the Risk of Fracture: Secondary Analysis of a Randomized Controlled Trial and an Updated Meta-Analysis
Creators: name: Meyer, H.E.
name: Baron, J.A.
name: Garcia Lopez, M.
name: Søgaard, A.J.
name: Omsland, T.K.
Publisher: name: Blackwell Publishing Ltd
Year: 2018

description: High plasma homocysteine is a risk factor for osteoporotic fractures. Several studies have assessed the possible preventive effect of homocysteine-lowering B-vitamin treatment on the risk of fracture with inconclusive results. In the current study, we include new results from the Aspirin Folate Polyp Prevention Study (AFPPS) together with an updated meta-analysis of randomized controlled trials (RCTs). Our objective was to determine whether there is an association between homocysteine-lowering B-vitamin treatment and the risk of fracture. The AFPPS trial was performed between 1994 and 2004 in nine clinical centers in the United States, and 1021 participants were randomized to a daily folic acid dose of 1 mg (n = 516) or placebo (n = 505). The main outcome was fracture of any type. In addition, we analyzed the risk of hip fracture. In the meta-analysis, studies were identified following a search strategy in electronic database and by hand searching. Risk ratio with 95% confidence interval (CI) was chosen for pooled analyses. In the AFPPS, no statistically significant association was found between folic acid treatment and fractures of any type (risk ratio [RR] = 0.95; 95% CI 0.61–1.48) or hip fracture (RR = 0.98; 95% CI 0.25–3.89). In the meta-analysis, six RCTs were included with a total of 36,527 participants. For interventions including folic acid and/or vitamin B12, the pooled RR for treatment was 0.97 (95% CI 0.87–1.09) for fractures of any type (n = 1199) and 1.00 (95% CI 0.81–1.23) for hip fractures (n = 335). In conclusion, no association was found between homocysteine-lowering treatment with B vitamins (folic acid and vitamin B12) and the risk of fracture.
Nonlinear Power Spectral Densities for the Harmonic Oscillator
Creators: name: Hauer, B. D.
name: Maciejko, J.
name: Davis, J. P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Other Condensed Matter (cond-mat.other)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, we discuss a general procedure by which nonlinear power spectral densities (PSDs) of the harmonic oscillator can be calculated in both the quantum and classical regimes. We begin with an introduction of the damped and undamped classical harmonic oscillator, followed by an overview of the quantum mechanical description of this system. A brief review of both the classical and quantum autocorrelation functions (ACFs) and PSDs follow. We then introduce a general method by which the kth-order PSD for the harmonic oscillator can be calculated, where $k$ is any positive integer. This formulation is verified by first reproducing the known results for the $k = 1$ case of the linear PSD. It is then extended to calculate the second-order PSD, useful in the field of quantum measurement, corresponding to the $k = 2$ case of the generalized method. In this process, damping is included into each of the quantum linear and quadratic PSDs, producing realistic models for the PSDs found in experiment. These quantum PSDs are shown to obey the correspondence principle by matching with what was calculated for their classical counterparts in the high temperature, high-Q limit. Finally, we demonstrate that our results can be reproduced using the fluctuation-dissipation theorem, providing an independent check of our resultant PSDs.
description: 27 pages, 5 figures
Twenty Years of Communication Intervention Research With Individuals Who Have Severe Intellectual and Developmental Disabilities
Creators: name: Sevcik, Rose
name: Snell, Martha E.
name: McLean, Lee
name: Ogletree, Billy T.
name: Brady, Nancy
name: Sylvester, Lorraine
name: Siegel, Ellin
name: Mineo, Beth
name: Paul, Diane
name: Romski, Mary Ann
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: This literature review was conducted to evaluate the current state of evidence supporting communication interventions for individuals with severe disabilities. Authors reviewed 116 articles published between 1987 and 2007 in refereed journals meeting three criteria: (a) described a communication intervention, (b) involved one or more participants with severe disabilities, and (c) addressed one or more areas of communication performance. Many researchers failed to report treatment fidelity or to assess basic aspects of intervention effects including generalization, maintenance, and social validity. The evidence reviewed indicates that 96% of the studies reported positive changes in some aspects of communication. These findings support the provision of communication intervention to persons with severe disabilities. Gaps in the research were reported with recommendations for future research.
Governance models for nature-based solutions: Seventeen cases from Germany
Creators: name: Zingraff-Hamed, Aude
name: Hüesker, Frank
name: Albert, Christian
name: Brillinger, Mario
name: Huang, Joshua
name: Lupp, Gerd
name: Scheuer, Sebastian
name: Schlätel, Mareen
name: Schröter, Barbara
Publisher: name: Humboldt-Universität zu Berlin
Year: 2020
Subjects: subject: Financing instruments
subject: Flood risk mitigation
subject: Institutional structures
subject: Polycentric governance
subject: River Management
subject: Stakeholder participation
subject: 320 Politikwissenschaft (Politik und Regierung)

description: Nature-based solutions (NBS) for mitigating climate change are gaining popularity. The number of NBS is increasing, but research gaps still exist at the governance level. The objectives of this paper are (i) to give an overview of the implemented NBS for flood risk management and mitigation in Germany, (ii) to identify governance models that are applied, and (iii) to explore the differences between these models. The results of a hierarchical clustering procedure and a qualitative analysis show that while no one-size-fits-all governance model exists, polycentricism is an important commonality between the projects. The study concludes by highlighting the need for further research on traditional governance model reconversion and paradigm changes. We expect the findings to identify what has worked in the past, as well as what is important for the implementation of NBS for flood risk management in future projects.
Final report on coordination of training activities
Creators: name: ARIES WP3 Members
Publisher: name: Zenodo
Year: 2020

description: This report describes the extent of ongoing proposed training activities on particle accelerators in
 Europe, as well as their coordination and interaction.
 The data used for the report is collected by carrying out a web-based survey. In total, 90 institutes and companies from 21 countries have participated in the ARIES survey on “Training in Accelerator Science”. Out of 90 responders, 50 responders were universities, 28 responders were national and international laboratories and 12 were companies.
 The report presents the provision of training, trainee numbers, training time, training subjects of the responding institutes, including training needs of companies. Coordination of training activities - accelerator schools, developments of MOOCs and use of facilities – is also outlined.
description: {"references": ["ARIES Del2.3"]}
Heat flux dynamics in dissipative cascaded systems
Creators: name: Lorenzo, Salvatore
name: Farace, Alessandro
name: Ciccarello, Francesco
name: Palma, G. Massimo
name: Giovannetti, Vittorio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the dynamics of heat flux in the thermalization process of a pair of identical quantum system that interact dissipatively with a reservoir in a {\it cascaded} fashion. Despite the open dynamics of the bipartite system S is globally Lindbladian, one of the subsystems "sees" the reservoir in a state modified by the interaction with the other subsystem and hence it undergoes a non-Markovian dynamics. As a consequence, the heat flow exhibits a non-exponential time behaviour which can greatly deviate from the case where each party is independently coupled to the reservoir. We investigate both thermal and correlated initial states of $S$ and show that the presence of correlations at the beginning can considerably affect the heat flux rate. We carry out our study in two paradigmatic cases -- a pair of harmonic oscillators with a reservoir of bosonic modes and two qubits with a reservoir of fermionic modes -- and compare the corresponding behaviours. In the case of qubits and for initial thermal states, we find that the trace distance discord is at any time interpretable as the correlated contribution to the total heat flux.
description: Final accepted version
Ghosts in classes of non-local gravity
Creators: name: De Felice, Antonio
name: Sasaki, Misao
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a class of non-local gravity theories where the Lagrangian is a function of powers of the inverse d'Alembertian operator acting on the Ricci scalar. We take an approach in which the non-local Lagrangian is made local by introducing auxiliary scalar fields, and study the degrees of freedom of the localized Lagrangian. We find that among the auxiliary scalar fields introduced, some of them are always ghost-like. That is, in the Einstein frame they develop a negative kinetic term. Because of this, except for a particular case already known in the literature, in general, it is not clear how to quantize these models and how to interpret this theory in the light of standard field theory.
description: 13 pages
Evidence for Reciprocal Interaction Effects Among Adults with Self-Injury and Their Caregivers
Creators: name: Clary, Jamie
name: Harper, Vickie N.
name: Wolff, Jason J.
name: Bodfish, James W.
name: Symons, Frank J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Patterns of caregiver responses to client adaptive behavior were compared between adults with intellectual disabilities with and without self-injurious behavior. Participants with moderate to profound intellectual disability and self-injury (n = 89) and age/IQ matched control participants (n = 20) were selected from a large sample of adults living in a regional residential center. Approximately 45 minutes of direct observation data were collected for each participant during unstructured leisure time. Data were sequentially analyzed and Yule’s Q scores derived and compared among groups. Results indicated that caregivers were more responsive to prosocial initiations and adaptive engagement among individuals with severe self-injurious behavior than to those with mild or no self-injurious behavior and that these responses were more likely to be in the form of a demand.
MOESM23 of ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia
Creators: name: Swindell, William
name: Kruse, Colin
name: List, Edward
name: Berryman, Darlene
name: Kopchick, John
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 23. 61 gene signature for prediction of ALS patient survival. The table lists the 61 genes incorporated into the final Cox PH regression model developed to predict ALS patient survival. Columns 2 and 3 provide hazard ratio (HR) estimates from unigenic Cox PH models, which were fit with five predictor variables, including expression of the gene listed in column 1 with four covariates (age, sex, site of onset, cohort). The second column gives the HR estimate with 95% confidence limits (HR > 1: increased expression = worse survival; HR
Oscillating statistics of transitive dynamics
Creators: name: Catsigeras, Eleonora
Publisher: name: arXiv
Year: 2015
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37A05, 28DXX, 37A60

description: We prove that topologically generic orbits of C0 transitive and non-uniquely ergodic dynamical systems, exhibit an extremely oscillating asymptotical statistics. Precisely, the minimum weak* compact set of invariant probabilities, that describes the asymptotical statistics of each orbit of a residual set, contains all the ergodic probabilities. If besides f is ergodic with respect to the Lebesgue measure, then also Lebesgue-almost all the orbits exhibit that kind of extremely oscillating statistics.
description: This revised version has some new paragraphs at the introduction according to the suggestion of the referee
Abschied von der Volkskirche?
Creators: name: Raab-Straube, Albrecht
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 22 Nr. 6 (1993): Internationale katholische Zeitschrift Communio, Band 22, Heft 6
Parenting Young Children with and Without Fragile X Syndrome
Creators: name: Sterling, Audra
name: Fleming, Kandace
name: Skinner, Debra
name: Warren, Steven F.
name: Barnum, Leah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The purpose of this study was to examine maternal parenting styles across age-matched siblings using a within-family design, in which one child has Fragile X syndrome. Thirteen families participated; children were aged 16 to 71 months. Mothers completed several videotaped activities with each child separately as well as an interview. Mothers used a consistent, responsive style with both children, using the same degree of positive affect and warmth. Differences included using more behavior management strategies with the child with Fragile X and a conversational style of interaction with the sibling. Differences in approaches suggest the mothers adapted to the developmental differences between the children. The interview data supported these findings; mothers were aware of the changes made to accommodate the developmental differences.
How subgroup analyses can miss the trees for the forest plots: A simulation study
Creators: name: Baron, J.A.
name: Jonsson Funk, M.
name: Webster-Clark, M.
name: Westreich, D.
Publisher: name: Elsevier USA
Year: 2020

description: Objectives: Subgroup analyses of clinical trial data can be an important tool for understanding when treatment effects differ across populations. That said, even effect estimates from prespecified subgroups in well-conducted trials may not apply to corresponding subgroups in the source population. While this divergence may simply reflect statistical imprecision, there has been less discussion of systematic or structural sources of misleading subgroup estimates. Study Design and Setting: We use directed acyclic graphs to show how selection bias caused by associations between effect measure modifiers and trial selection, whether explicit (e.g., eligibility criteria) or implicit (e.g., self-selection based on race), can result in subgroup estimates that do not correspond to subgroup effects in the source population. To demonstrate this point, we provide a hypothetical example illustrating the sorts of erroneous conclusions that can result, as well as their potential consequences. We also provide a tool for readers to explore additional cases. Conclusion: Treating subgroups within a trial essentially as random samples of the corresponding subgroups in the wider population can be misleading, even when analyses are conducted rigorously and all findings are internally valid. Researchers should carefully examine associations between (and consider adjusting for) variables when attempting to identify heterogeneous treatment effects.
Perseveration in the Connected Speech of Boys with Fragile X Syndrome with and Without Autism Spectrum Disorder
Creators: name: Martin, Gary E.
name: Moskowitz, Lauren
name: Roberts, Joanne E.
name: Helm-Estabrooks, Nancy
name: Sideris, John
name: Vanderbilt, Jacqueline
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Verbal perseveration is a frequently reported language characteristic of males with Fragile X syndrome and may be a defining feature or hallmark of the syndrome. We compared the verbal perseveration of boys with Fragile X syndrome with (n = 29) and without (n = 30) autism spectrum disorder, boys with Down syndrome (n = 27), and typically developing boys (n = 25) at similar nonverbal mental ages. During a social interaction, boys with both Fragile X syndrome and autism spectrum disorder produced significantly more topic perseveration than all other groups. In social interaction as compared to narration, boys with Fragile X syndrome (regardless of autism status) produced significantly more topic perseveration. These findings suggest that autism status, as well as language sampling context, affect perseveration in boys with Fragile X syndrome.
Identification of research gaps in organic Pome, Stone Citrus production and and recommendations for further research
Creators: name: Vavra, Radek
name: de Simone, Ambra
name: Verrastro, Vincenzo
name: Kelderer, Markus
name: Mora-Vargas, Alfredo
name: Egerer, Sophie
name: Kienzle, Jutta
Publisher: name: Zenodo
Year: 2023

description: Organic farming is knowledge intensive. Hence, knowledge sharing is pivotal to support farmers in enhancing their organic fruit production systems.
The overall aim of BIOFRUTINET is to collect, evaluate and select locally known strategies and best practices in organic fruit growing and make them easily accessible to farmers across Europe. The specific objective of WP3 is to evaluate the existing ready-for-practise knowledge and the gaps collected in WP2, and to select those solutions that are effective, easy to implement and representative for pome, stone and citrus organic growers.
In WP2, the consortium of BIOFRUITNET sampled precise information from 250 farmers over 18 European countries collecting information on the importance of pests and diseases, on practices used to fight them, their relative efficiency, and the need for further information and knowledge gaps. From the collected information, the consortium initiated a multi-actor evaluation process with fruit growing experts to assess and complete these results to get a complete and accurate picture of the situation.
This document reports on the knowledge gaps in organic fruit growing and propose recommendations for organic pome, stone and citrus further research.
For each of the fruit groups, knowledge gaps and recommendations are given for the 4 most important topics identified in WP3. These topics are the results of the design of 18 matrices (Task 3.1) and go as follows: Pest, diseases, functional biodiversity, and rootstock & varieties.
An Investigation of Narrative Ability in Boys with Autism and Fragile X Syndrome
Creators: name: Hogan-Brown, Abigail L.
name: Losh, Molly
name: Mueffelmann, Deborah J.
name: Martin, Gary E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Whereas pragmatic language difficulties are characteristic of both autism and Fragile X syndrome, it is unclear whether such deficits are qualitatively similar or whether certain skills are differentially affected. This study compared narrative competence in boys with autism, Fragile X syndrome, Down syndrome, and typical development. Results revealed that an interaction between diagnosis and nonverbal mental age predicted narrative microstructure (e.g., complex syntax) but not macrostructure (e.g., thematic maintenance). Correlations with FMR1-related variation were investigated in children with Fragile X syndrome. While CGG repeat length was associated with many language characteristics, nonverbal IQ appeared to mediate these relationships. These findings are an important step toward understanding narrative abilities in boys with and without the FMR1 mutation.
Exkommunikation für Schwangerschaftskonfliktberatung?
Creators: name: Demel, Sabine
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 22 Nr. 6 (1993): Internationale katholische Zeitschrift Communio, Band 22, Heft 6
Fermionic non-Abelian fractional Chern insulators from dipolar interactions
Creators: name: Wang, Dong
name: Liu, Zhao
name: Liu, Wu-Ming
name: Cao, Jun-Peng
name: Fan, Heng
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study fermions on a triangular lattice model that exhibits topological flatbands characterized by nonzero Chern numbers. Our scheme stems from the well-known Hofstadter model but the next-nearest-neighbor hopping is introduced, which is crucial for tuning the lowest band to be nearly flat. Differing from previous proposals with the necessity of multiparticle interactions, we consider the more realistic long-range dipolar interaction combined with two-body short-range attractions between fermions. We show the realization of the non-Abelian $ν=1/2$ Moore-Read fractional Chern insulators, and strong evidence for the existence of the more exotic $ν=3/5$ Read-Rezayi fractional Chern insulators. Our results provide insights for the experimental realization of these exotic states by realistic two-body interactions and thus facilitates the implementation of the universal topological quantum computation.
description: 5+pages, 6 figures, published version
Additional file 1: of Are you ready? A systematic review of pre-departure resources for global health electives
Creators: name: Kalbarczyk, Anna
name: Nagourney, Emily
name: Martin, Nina
name: Chen, Victoria
name: Bhakti Hansoti
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Search Terms by Database. This file contains the search terms used in five different databases for the systematic review. (DOCX 13 kb)
Additional file 1: of Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates
Creators: name: Vonarburg, Cédric
name: Loetscher, Marius
name: Spycher, Martin
name: Kropf, Alain
name: Illi, Marlies
name: Salmon, Sharon
name: Roberts, Sean
name: Steinfuehrer, Karin
name: Campbell, Ian
name: Koernig, Sandra
name: Bain, Joseph
name: Edler, Monika
name: Baumann, Ulrich
name: Miescher, Sylvia
name: Metzger, Dennis
name: Schaub, Alexander
name: Käsermann, Fabian
name: Zuercher, Adrian
Publisher: name: Figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Figure S1. Aerosol characterization upon nebulization of distinct Ig formulations. PBS and proline formulations of diverse Ig preparations were nebulized side by side. Mass median diameter (A), total output rate (B) and respirable fraction (C) were measured using laser diffraction. Figure S2. Chromatograms of IgA and IgAM separated by size exclusion. A.B. Chromatograms of IgA (5%) (A) and IgAM (5%) (B) separated by size exclusion are represented. Blue chromatograms refer to the nebulized (N) formulation. Red chromatograms refer to the non-nebulized, or control (Co), formulation. Figure S3. Nebulized Igs retain their function in an in vitro model of Shigella infection. Polarized Caco-2 cell monolayers were infected overnight with Shigella flexneri alone or in presence of nebulized or non-nebulized Ig formulations. A. Quantitative analysis of infected areas was determined from laser scanning confocal microscopy pictures using ImageJ software. B-D. Basolateral secretion of TNF-α (B), CXCL8 (C), and CCL3 (D) was measured by ELISA. Non-infected Caco-2 cell monolayers served as a control. Figure S4. Lung tissue from IgG, IgA, IgAM- and vehicle-treated animals (NHP) were collected 72 h post-exposure (4th inhalation) and were fixed and embedded in paraffin. Tissue sections were analyzed for IgG (A) and IgA (B) using specific secondary antibody coupled to HRP. For each detection antibody, detection of lung tissue obtained from a vehicle-treated animal is shown. It represents the level of background of the detection antibody. (PDF 717 kb)
Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions
Creators: name: Barry, E.L.
name: Hamilton, S.R.
name: Morris, J.S.
name: Bartley, A.N.
name: Figueiredo, J.C.
name: Passarelli, M.N.
name: McKeown-Eyssen, G.
name: Baron, J.A.
name: Goel, A.
name: Corley, L.
name: Wei, W.
name: Bresalier, R.S.
name: Mesa, G.H.
name: Ahnen, D.J.
name: Mehta, T.
Publisher: name: Public Library of Science
Year: 2021

description: Background Adenomas and serrated lesions represent heterogeneous sets of early precursors in the colorectum with varying malignant potential. They are often distinguished by their histopathologic differences, but little is known about potential differences in regulation of epithelial proliferation and apoptosis. Methods We conducted a protein expression analysis using tissue microarrays of 625 colorectal adenomas and 142 serrated lesions to determine potential differences in regulation of epithelial proliferation and apoptosis. We quantitated proliferation with Ki-67; apoptosis with activated caspase-3 (CASP3); up- and down-regulators of proliferation with cyclin D1, p16INK2, and p21Cip1; and apoptosis regulators with BAX, BCL2, and survivin. Linear mixed effects models and circos diagrams were used to determine relationships among expression and lesion characteristics. Results Adenomas had a significantly higher CASP-3 labeling index (LI) than serrated lesions, resulting in a lower net growth ratio (Ki-67 LI/activated CASP-3 LI, p-value<0.0001). Cyclin D1 LI, p16 LI and p21 LI were lower in adenomas compared to serrated lesions, while expression of both BCL2 and BAX were higher (p <0.001). Among adenomas, cyclin D1 LI and p16 LI levels increased with greater villous component, and the highest BAX expression was detected in adenomas larger than 2 cm (both p<0.0001). Right-sided adenomas had higher CASP3 LI than left colorectal adenomas (p = 0.008). Significant differences in cyclin D1 LI, p21 LI and survivin LI were also observed across histopathologic subtypes of serrated lesions. Conclusions Our findings demonstrate different patterns of regulatory protein expression in adenomas than serrated lesions, especially involving apoptosis.
Discrepancies in Parent and Teacher Ratings of Social-Behavioral Functioning of Children With Chromosome 22q11.2 Deletion Syndrome: Implications for Assessment
Creators: name: Shashi, Vandana
name: Curtiss, Kathleen
name: Schoch, Kelly
name: Wray, Emily
name: Hooper, Stephen R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Children with 22q11.2 deletion syndrome exhibit high rates of social-behavioral problems, creating an area in need of intervention. This study obtained parent and teacher ratings on the CBCL/TRF of 67 children with 22q11DS and 57 controls. Results indicated significant differences in social-behavioral functioning of children with 22q11DS compared to controls, depending on rater type. Parents reported greater internalizing, withdrawal, and social problems in children with 22q11DS while teachers perceived few differences between groups. Correlational analyses indicated weak concordance between parent and teacher reports, with no significant correlations on three summary scales. The findings support the use of multiple informants when evaluating the social-behavioral functioning of children with 22q11DS, and suggest that interpretations based on one informant/setting should be made cautiously.
Zur bisherigen öffentlichen Diskussion um den neuen Weltkatechismus
Creators: name: Eberle, Jürgen
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 22 Nr. 6 (1993): Internationale katholische Zeitschrift Communio, Band 22, Heft 6
Physiological Arousal in Autism and Fragile X Syndrome: Group Comparisons and Links With Pragmatic Language
Creators: name: Klusek, Jessica
name: Martin, Gary E.
name: Losh, Molly
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: This study tested the hypothesis that pragmatic (i.e., social) language impairment is linked to arousal dysregulation in autism spectrum disorder (ASD) and fragile X syndrome (FXS). Forty boys with ASD, 39 with FXS, and 28 with typical development (TD), aged 4–15 years, participated. Boys with FXS were hyperaroused compared to boys with TD but did not differ from boys with ASD. Dampened vagal tone predicted pragmatic impairment in ASD, and associations emerged between cardiac activity and receptive/expressive vocabulary across groups. Findings support autonomic dysfunction as a mechanism underlying pragmatic impairment in ASD and suggest that biophysiological profiles are shared in ASD and FXS, which has implications for understanding the role of fragile X mental retardation-1 (FMR1, the FXS gene) in the pathophysiology of ASD.
Aqueous compatibility of 15 pharmaceutical antimicrobial preservatives with the macrocycles cucurbit[7]uril and para-sulfonatocalix[4]arene
Creators: name: Nastatos, Xenia L.
name: Mansour, Elissar
name: Gu, Alice
name: Wheate, Nial J.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The compatibility of 15 antimicrobial preservatives used in liquid/semi-solid pharmaceutical dosage formulations with the macrocycles cucurbit[7]uril (CB[7]) and para-sulfonatocalix[4]arene (sCX[4]) was examined by 1H NMR. A preservative was deemed to be compatible with one, or both, of the macrocycles if there was no evidence of host-guest complex formation. Eight preservatives (benzoic acid, ethanol, glycerine, methyl paraben, potassium sorbate, propylene glycol, sodium ethylenediaminetetraacetic acid, and sodium metabisulfite) were determined to be compatible with both CB[7] and sCX[4]. Three preservatives (benzalkonium chloride, cetrimide, and chlorhexidine) were determined to be not compatible with either macrocycle, whereas chlorobutanol and chlorocresol were found to be compatible with sCX[4] but not with CB[7]. Phenoxyethanol was incompatible with sCX[4] but possibly incompatible with CB[7] depending on the concentration of the preservative used with the cucurbituril. Finally, sodium propanoate was compatible with sCX[4] but only possibly compatible with CB[7].
Additional file 1: of One size does not fit all: HIV prevalence and correlates of risk for men who have sex with men, transgender women in multiple cities in Papua New Guinea
Creators: name: Hakim, Avi
name: Coy, Kelsey
name: Badman, Steven
name: Barne Willie
name: Narokobi, Rebecca
name: Gabuzzi, Josephine
name: Pekon, Simon
name: Kupul, Martha
name: Hou, Parker
name: Herick Aeno
name: Boli, Ruthy
name: Nembari, Joshua
name: Ase, Sophie
name: Angelyne Amos
name: Dala, Nick
name: Weikum, Damian
name: Callens, Steven
name: Kaldor, John
name: Vallely, Andrew
name: Kelly-Hanku, Angela
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: FSW Questionnaire, FSW Questionnaire, Quantitative interview questionnaire used with FSW participants. (DOCX 100 kb)
Kasus penguasaan Lahan di Kota Pematangsiantar
Creators: name: Beatric Siahaan
Publisher: name: Zenodo
Year: 2024

description: Artikel ini membahas tentang konflik penguasaan lahan di Pematangsiantar, yang melibatkan masyarakat lokal dan pewaris lahan. Masyarakat lokal yang telah lama tinggal di lahan tersebut mengklaim memiliki hak tradisional yang diakui oleh komunitas mereka, meskipun tidak tertulis. Mereka merasa terancam oleh tindakan pengusuran yang dilakukan oleh pewaris lahan, yang memiliki surat kepemilikan yang sah namun diperoleh dengan cara yang meragukan.

Konflik ini mencerminkan perbedaan antara hukum positif yang diatur dalam Undang-Undang Dasar 1945 dan hukum adat yang berlaku di masyarakat lokal. Masyarakat lokal berjuang untuk mempertahankan hak mereka atas tanah yang telah mereka huni selama bertahun-tahun, sementara pewaris lahan berpegang pada bukti kepemilikan yang sah.
Rule-Based Category Learning in Down Syndrome
Creators: name: Phillips, B. Allyson
name: Conners, Frances A.
name: Merrill, Edward
name: Klinger, Mark R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Rule-based category learning was examined in youths with Down syndrome (DS), youths with intellectual disability (ID), and typically developing (TD) youths. Two tasks measured category learning: the Modified Card Sort task (MCST) and the Concept Formation test of the Woodcock-Johnson-III ( Woodock, McGrew, & Mather, 2001 ). In regression-based analyses, DS and ID groups performed below the level expected for their nonverbal ability. In cross-sectional developmental trajectory analyses, results depended on the task. On the MCST, the DS and ID groups were similar to the TD group. On the Concept Formation test, the DS group had slower cross-sectional change than the other 2 groups. Category learning may be an area of difficulty for those with ID, but task-related factors may affect trajectories for youths with DS.
Evaluation of a Deep Neural Network for Automated Classification of Colorectal Polyps on Histopathologic Slides
Creators: name: Wei, J.W.
name: Kim, A.S.
name: Suriawinata, A.A.
name: Snover, D.C.
name: Abdollahi, B.
name: Ren, B.
name: Baron, J.A.
name: Barry, E.L.
name: Tomita, N.
name: Liu, X.
name: Hassanpour, S.
name: Lisovsky, M.
name: Vaickus, L.J.
Publisher: name: American Medical Association
Year: 2020

description: Importance: Histologic classification of colorectal polyps plays a critical role in screening for colorectal cancer and care of affected patients. An accurate and automated algorithm for the classification of colorectal polyps on digitized histopathologic slides could benefit practitioners and patients. Objective: To evaluate the performance and generalizability of a deep neural network for colorectal polyp classification on histopathologic slide images using a multi-institutional data set. Design, Setting, and Participants: This prognostic study used histopathologic slides collected from January 1, 2016, to June 31, 2016, from Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, with 326 slides used for training, 157 slides for an internal data set, and 25 for a validation set. For the external data set, 238 slides for 179 distinct patients were obtained from 24 institutions across 13 US states. Data analysis was performed from April 9 to November 23, 2019. Main Outcomes and Measures: Accuracy, sensitivity, and specificity of the model to classify 4 major colorectal polyp types: tubular adenoma, tubulovillous or villous adenoma, hyperplastic polyp, and sessile serrated adenoma. Performance was compared with that of local pathologists' at the point of care identified from corresponding pathology laboratories. Results: For the internal evaluation on the 157 slides with ground truth labels from 5 pathologists, the deep neural network had a mean accuracy of 93.5% (95% CI, 89.6%-97.4%) compared with local pathologists' accuracy of 91.4% (95% CI, 87.0%-95.8%). On the external test set of 238 slides with ground truth labels from 5 pathologists, the deep neural network achieved an accuracy of 87.0% (95% CI, 82.7%-91.3%), which was comparable with local pathologists' accuracy of 86.6% (95% CI, 82.3%-90.9%). Conclusions and Relevance: The findings suggest that this model may assist pathologists by improving the diagnostic efficiency, reproducibility, and accuracy of colorectal cancer screenings.
A novel thiosemicarbazide based chemosensor for colorimetric detection of Co2+ in commercial B12 vitamin and Co2+, Ni2+ simultaneously in aqueous media
Creators: name: Khereshki, Nasibeh Azizi
name: Mohammadi, Asadollah
name: Mousavi, Hassan Zavvar
name: Alizadeh, Nina
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: Plant Biology

description: In this study, a novel thiosemicarbazide-based Schiff-base chemosensor containing naphthalene moiety (TSNCS) was easily synthesised and used for colorimetric detection of Ni2+, Co2+ ions in real samples. Probe TSNCS displayed an obvious colour change from colourless to dark yellow in the presence of Co2+ and Ni2+ in aqueous acetonitrile solutions. The interaction-binding mode of probe TSNCS with Co2+ (TSNCS-Co2+) and Ni2+ (TSNCS-Ni2+) was found to be 1:1 based on Job’s plot analysis. The results showed that the chemosensor TSNCS could provide a rapid analytical method for naked-eye detection of Co2+ and Ni2+ with detection limits (LOD) of 0.0114 μM and 0.0168 μM, respectively. Furthermore, the TSNCS-based test papers strips were successfully used for the rapid detection of Co2+ and Ni2+ ions in an aqueous solution. In addition, probe TSNCS was applied for the qualitative and quantitative analysis of Co2+ in the commercial vitamin B12 and real water samples.
Caregiver Strain and Sensory Features in Children With Autism Spectrum Disorder and Other Developmental Disabilities
Creators: name: Kirby, Anne V.
name: Baranek, Grace T.
name: White, Tamira J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Caring for children with disabilities contributes to increased levels of parent stress, or caregiver strain. However, the potential relationship of sensory features to strain among caregivers of children with autism spectrum disorder (ASD) and other developmental disabilities (DD) is unknown. Sensory features include over-reactions, under-reactions, and unusual interests in sensations, which may negatively impact family functioning. This descriptive study confirmed three caregiver strain types (i.e., objective, subjective internalized, subjective externalized) and explored differences among ASD (n=71) and DD (n=36) groups, with the ASD group reporting higher levels. Furthermore, this study explored the contribution of sensory features to caregiver strain, finding differential contributions to strain in the ASD group and covariate contributions (i.e., child cognition, mother’s education) in the DD group.
Die bloße Vernunft innerhalb der Grenzen der Religion
Creators: name: Boulnois, Olivier
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 22 Nr. 6 (1993): Internationale katholische Zeitschrift Communio, Band 22, Heft 6
Interaction of Aldosterone and Extracellular Volume in the Pathogenesis of Obesity-Associated Kidney Disease: A Narrative Review
Creators: name: Bomback, Andrew S.
name: Klemmer, Philip J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Obesity and obesity-associated kidney injuries have played an important role in the rising prevalence of chronic kidney disease (CKD). The link between obesity and kidney disease begins with obesity's well-known associations with diabetes and hypertension, the two leading etiologies of CKD. However, a growing body of evidence suggests that elevated aldosterone levels and expanded extracellular volume are key components of obesity-induced renal disease via aldosterone's non-epithelial effects on the kidney. Highlighting these blood pressure- and diabetes-independent mechanisms of kidney injury in obesity allows an exploration of whether mineralocorticoid receptor blockade, coupled with weight loss and salt restriction, is an optimal treatment for overweight CKD patients.
UNLEASHING SUCCESS: A COMPREHENSIVE EVALUATION OF LEADERSHIP COMPETENCIES FOR PROJECT DELIVERY IN UAE SERVICE INDUSTRIES
Creators: name: UPENDRA B
name: HEMANTH KUMAR V
name: SUHASHINI A
name: RENJU K MATHAI
Publisher: name: Zenodo
Year: 2023
Subjects: Emotional Intelligence, Leadership Competencies, Project Management, Service Industry Management, Managerial Abilities.

description: Abstract
The service industry in the UAE is highly competitive, and the success of projects in this sector depends on effective leadership competencies. This study evaluating leadership competencies for the successful delivery of projects in the UAE service industries. While project management and leadership are distinct, project managers can enhance their skills by developing leadership capabilities through creativity and innovation. Team performance is critical in both project management and leadership, and key leadership skills such as motivation, inspiration, listening, influencing, and team building are crucial for project managers. However, many service industry projects in the UAE fail due to inadequate leadership styles, project procedures, and methods. This research emphasizes the importance of identifying top leadership competencies, including emotional intelligence (EA), managerial ability (MA), and intellectual ability (IA), to ensure successful project implementation in the UAE service industries. The evaluation of leadership competencies can contribute to effective project delivery, enhancing the performance and success of projects in the UAE service industries. The findings of this study can assist service industry organizations in the UAE to identify the critical leadership competencies required for project success and provide a framework for enhancing the leadership skills of project managers.
Particle Discrimination in TeO$_{2}$ Bolometers using Light Detectors read out by Transition Edge Sensors
Creators: name: Schäffner, K.
name: Angloher, G.
name: Bellini, F.
name: Casali, N.
name: Ferroni, F.
name: Hauff, D.
name: Nagorny, S. S.
name: Pattavina, L.
name: Petricca, F.
name: Pirro, S.
name: Pröbst, F.
name: Reindl, F.
name: Seidel, W.
name: Strauss, R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: An active discrimination of the dominant $α$-background is the prerequisite for future neutrinoless double-beta decay experiments based on TeO$_{2}$ bolometers. We investigate such $α$-particle rejection in cryogenic TeO$_{2}$ bolometers by the detection of Cherenkov light. For a setup consisting of a massive TeO$_{2}$ crystal (285 g) and a separate cryogenic light detector, both using transition edge sensors as temperature sensors operated at around 10 mK, we obtain an event-by-event identification of e/$γ$- and $α$-events. We find in the energy interval ranging from 2400 keV to 2800 keV and covering the Q-value of the neutrinoless double-beta decay of $^{130}$Te a separation of the means of the two populations of 3.7 times their width.
description: 8 pages, 7 figures
Moroccan EFL Learners' Perceptions of Stative Progressives Evolving Semantics: New Tendencies in Understanding Stative Verbs
Creators: name: Dr. Saber Abou El Fadl
Publisher: name: Zenodo
Year: 2023
Subjects: Duality, Interlanguage, Input, Imperfective, Non-standard meanings, Statives, Emergence.

description: Abstract
The present study investigates the perception of EFL Moroccan learners towards imperfective aspectual meanings. Employing a corpus-data semantic-driven approach, the inquiry assesses the acceptability of stative progressives as a non-standard connotation of statives. For this purpose, a grammaticality judgment test is implemented, surveying sixty Moroccan University English learners (n=60; BA=30, MA=30). The findings indicate sensitivity to stative progressives, yet without significant variance between the study groups. Instruction, along with other cognitive mechanisms, may play a prominent role in these forms' emergence. Further, they can decisively aid material development, offering a reclassification of the dynamic/stative dichotomous meanings and emphasizing the role of input in tandem with other cognitive factors to expedite -ed/-ing emergence within the learners' interlanguage.
Exploring mathematics anxiety and potential associated environmental antecedents amongst a group of adult learners
Creators: name: O Hanlon, Adrian
Publisher: name: University of Limerick
Year: 2023
Subjects: classificationCode: 49
subject: Mathematical sciences

description: The Further Education and Training (FET) sector has often been referred to the ‘Cinderella’ sector of the Irish education system. It is often overlooked and undervalued, mainly due to its fragmented provision, as well as an unclear and diverse identify. Almost €800 million of funding is invested by SOLAS annually in FET, serving around 200,000 unique learners each year. Mathematics Anxiety affects learners at all levels of the education system including FET. Indeed, the concept of mathematics anxiety is prevalent in research in order to understand the fear and anxiety that learners exhibit in dealing with mathematics. The vast majority of research in mathematics anxiety has focused on primary school, post primary school and higher education, where FET has been ignored to a significant extent. The study comprised of a sequential mixed method approach, the quantitative element was a MAS UK (Mathematics Anxiety Scale) questionnaire (n=15) and the qualitative element was a mathematics life story interview (n=8). The findings show that mathematics anxiety existed at varying levels among these mature students, and that there are significant environmental antecedents that contribute to the level of anxiety experienced.