cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Metales totales y biodisponibles en sedimentos recientes de la laguna Los Patos, estado Sucre, Venezuela
Creators: name: Senior, William
name: Márquez, Aristide
name: Martínez, Gregorio
name: González, Ángel
Publisher: name: figshare
Year: 2016
Subjects: subject: 40502 Chemical Oceanography
subject: FOS: Earth and related environmental sciences

description: The objective of this research was to assess the total metal content and bioavailability of these elements in the sediment of the Duck‘ lagoon (Laguna Los Patos), Sucre state, Venezuela. By using extractions with HNO3: HClO4: HCl in 3:1:1 ratio to total metals and acetic acid to 10%for the bioavailable fraction, was determined by atomic absorption spectrometry with air acetylene flame, that total metals show at their peak concentrations (μg/g), a descending order: Fe (1304.13) > Mn (177.14) > Zn (31.74) > Pb (12.62) > Cu (10.27 )> Cr ( 5.92) > Cd (0.56), associated with the particles of the kind of mud. The lagoons presents a deterioration with focus of lead pollution in the central part and copper, nickel and lead towards the far south, where a sewage treatment plant is located. Iron, manganese, copper, zinc and nickel are in the bioavailablefraction with values between 2.01-99.62%; 12.00-52.82%; 4.53- 18.88%; 26.52-45.91% y 2.93-91.59% respectively, of the total of each present metal in the sediment. The heterogeneity observed in the distribution of residual and bioavailable fractions, reflects a wide variability of the sedimentary matrix. Moreover, the presence of these five metals in the bioavailable fraction shows a progressive risk for biota of the lagoon, due to the ability of these elements to bioaccumulate in organisms, suggesting a magnification of these impacts in the future, under the weak flow of the waters of this ecosystem.
Extending Exploration and Navigation Capabilities of the Atlas of Switzerland
Creators: name: Schmuki, Michael
name: Sieber, René
name: Hurni, Lorenz
Publisher: name: ETH Zurich
Year: 2019
Subjects: Atlas
Exploration
Navigation
Search
Map-Index
Timeline

description: Abstracts of the ICA, 1
description: ISSN:2570-2106
Silver(I) complexes with halo-substituted cyanoanilines: synthesis, characterization and antibacterial activity
Creators: name: Qian, Wei
name: Hao-Kun Yuan
name: Zhang, Ran
name: Fang, Rui-Qin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Four Ag(I) complexes, [Ag(L1)2](NO3) (1), [Ag(L2)(NO3)] (2), [Ag(L3)3](NO3) (3), and [Ag(L4)2](NO3) (4), with ligands derived from halo-containing cyanoanilines (L1 = 4-amino-3fluorobenzonitrile, L2 = 4-amino-3-chlorobenzonitrile, L3 = 4-amino-3-bromobenzonitrile, L4 = 4-amino-2-bromobenzonitrile) were synthesized and characterized by C, H, and N elemental analysis, IR and 1H NMR spectroscopy and single crystal X-ray diffraction. Complexes 1–4 crystallized in the triclinic space group C2/c, P2(1)/n, P-1 and C2/c, respectively. In 1 and 4, Ag+ is four-coordinate with L1 or L4 to form 1-D ∞{[Ag(L1/L4)2]+} polymeric cations. In 2, Ag+ is three-coordinate by two L2 ligands and one NO3− ligand to form a 1-D ∞{[Ag(L2)(NO3)]} zigzag chain. In 3, Ag+ is four-coordinate by L3 to form a dinuclear [Ag(L3)3]+ cation. The NO3− is a 4-connector bridging group in 1 and 3 and a 5-connector bridging group in 2 and 4. The intermolecular hydrogen bonds and Ag⋯O weak interactions play important roles in forming 3-D networks of 1–4. The antibacterial activities for 1–4 were evaluated against Bacillus subtilis, Staphylococcus aureus and Escherichia coli with MTT method. The antibacterial results indicated that 2 showed the best inhibitory activity against the test bacterial strains, and was as potent as chloramphenicol.
Assessing factors that influence graduate student burnout in health professions education and identifying recommendations to support their well-being
Creators: name: Matt, Isabel C
name: Jarstfer, Michael B
name: Anderson, Emili B
name: Harris, Suzanne C
name: Zeeman, Jacqueline M
Publisher: name: Public Library of Science (PLoS)
Year: 2025

description:
BACKGROUND: While well-being has become increasingly important in graduate education, limited information exists regarding factors contributing towards burnout and well-being in Pharmaceutical Sciences Doctor of Philosophy (PhD) students. This exploratory story aimed to identify factors influencing well-being and burnout in these students as well as identify recommendations to support their well-being. METHODS: A two-stage sampling approach was used: (1) purpose sample of Pharmaceutical Sciences PhD students at a public university were invited to participate in a semi-structured focus group or interview to explore factors contributing to PhD student burnout and well-being as well as solicit suggestions for strategies to improve their well-being; (2) Stratified sampling was used to assign participants into focus groups by All-But-Dissertation (ABD) status (i.e., pre-ABD candidates, ABD candidates) to explore experiences that may be unique to these students. Inductive coding and thematic analysis were used. RESULTS: Six PhD candidates participated in three sessions: three Pre-ABD candidates in one focus group, two ABD candidates in one focus group, and one ABD candidate in one interview. Participants identified relationships and aspects of curriculum and research (i.e., program design, completing milestones) as factors influencing their well-being. Factors influencing participants' burnout included curriculum and research stressors (e.g., cumulative exams, competing academic and research responsibilities), working overtime, unrealistic expectations, lack of work life balance, and financial burden. While relationships and curriculum and research were factors in both subgroups, unique aspects within these themes emerged between Pre-ABD and ABD participants. Participant recommendations to foster PhD student well-being included improving financial support and encouraging PhD connections. CONCLUSIONS: This study advances knowledge on factors influencing PhD student well-being and burnout, providing suggestions to improve their well-being. Findings highlight curriculum and research factors as well as relationship dynamics influence graduate student burnout and well-being. Findings contribute to broader conversations aimed to support student wellness and reduce burnout in higher education, informing the academy of focused areas and strategies to improve PhD student well-being.
Silver(I) complexes with halo-substituted cyanoanilines: Synthesis, characterization and antibacterial activity
Creators: name: Qian, Wei
name: Hao-Kun Yuan
name: Zhang, Ran
name: Fang, Rui-Qin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Four Ag(I) complexes, [Ag(L1)2](NO3) (1), [Ag(L2)(NO3)] (2), [Ag(L3)3](NO3) (3) and [Ag(L4)2](NO3) (4), with ligands derived from halo-containing cyanoanilines (L1 = 4-amino-3fluorobenzonitrile, L2 = 4-amino-3-chlorobenzonitrile, L3 = 4-amino-3-bromobenzonitrile, L4 = 4-amino-2-bromobenzonitrile) were synthesized and characterized by C, H and N elemental analysis, IR and 1H-NMR spectroscopy and single crystal X-ray diffraction. Complexes 1-4 crystallized in the triclinic space group C2/c, P2(1)/n, P-1 and C2/c, respectively. In 1 and 4, Ag+ is four-coordinate with L1 or L4 to form 1D ∞{[Ag(L1/L4)2]+} polymeric cations. In 2, Ag+ is three-coordinate by two L2 ligands and one NO3- ligand to form a 1D ∞{[Ag(L2)(NO3)]} zigzag chain. In 3, Ag+ is four-coordinate by L3 to form a dinuclear [Ag(L3)3]+ cation. The NO3- is a 4-connector bridging group in 1 and 3 and a 5-connector bridging group in 2 and 4. The intermolecular hydrogen bonds and Ag⋅⋅⋅O weak interactions play important roles in forming 3D networks of 1-4. The antibacterial activities for 1-4 were evaluated against B. subtilis, S. aureus and E. coli with MTT method. The antibacterial results indicated that 2 showed the best inhibitory activity against the test bacterial strains, and was as potent as chloramphenicol.
Topic Selection and Structure in the National Atlas of Switzerland
Creators: name: Vomsattel, Raphael
name: Sieber, René
name: Hurni, Lorenz
Publisher: name: ETH Zurich
Year: 2019
Subjects: Atlas Concept
Topic Selection
Thematic Navigation
National Atlas

description: Abstracts of the ICA, 1
description: ISSN:2570-2106
Newly discovered round mound beside the Trent at Hull Bank, Hargate Pasture, Egginton
Creators: name: Guilbert, Graeme
name: Garton, Daryl
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 19-32
description: Paper on a round mound identified within a pasture-field named Hull Bank, situated at the edge of a gravel-terrace within the floor of the Trent Valley, close to the Trent/Dove confluence. The paper discusses the implications of the fact that it had not previously been noted as being of archaeological interest.
Are modern metaheuristics successful in calibrating simple conceptual rainfall–runoff models?
Creators: name: Piotrowski, Adam P.
name: Napiorkowski, Maciej J.
name: Jaroslaw J. Napiorkowski
name: Osuch, Marzena
name: Kundzewicz, Zbigniew W.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Statistics
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: In recent years sampling approaches have been used more widely than optimization algorithms to find parameters of conceptual rainfall–runoff models, but the difficulty of calibration of such models remains in dispute. The problem of finding a set of optimal parameters for conceptual rainfall–runoff models is interpreted differently in various studies, ranging from simple to relatively complex and difficult. In many papers, it is claimed that novel calibration approaches, so-called metaheuristics, outperform the older ones when applied to this task, but contradictory opinions are also plentiful. The present study aims at calibration of two simple lumped conceptual hydrological models, HBV and GR4J, by means of a large number of metaheuristic algorithms. The tests are performed on four catchments located in regions with relatively similar climatic conditions, but on different continents. The comparison shows that, although parameters found may somehow differ, the performance criteria achieved with simple lumped models calibrated by various metaheuristics are very similar and differences are insignificant from the hydrological point of view. However, occasionally some algorithms find slightly better solutions than those found by the vast majority of methods. This means that the problem of calibration of simple lumped HBV or GR4J models may be deceptive from the optimization perspective, as the vast majority of algorithms that follow a common evolutionary principle of survival of the fittest lead to sub-optimal solutions.
OESA-EQ
Creators: name: Farrell, Callyn
name: Slaughter, Virginia
name: Mulvihill, Aisling
Publisher: name: figshare
Year: 2021
Subjects: classificationCode: 520302
subject: Clinical psychology
classificationCode: 520102
subject: Educational psychology
classificationCode: 520106
subject: Psychology of ageing

description: The OESA-EQ is a self-report tool, comprised of 147 items and is completed by a parent/caregiver. The OESA-EQ gathers demographic information, information on the breadth and intensity of OESA participation, and explores facilitators and barriers to participation across three levels of engagement (i.e., fully engaged, partially engaged, and considered engagement). Informed by the ICF-CY, the OESA-EQ aims to collect meaningful information regarding parents’ perceptions of the facilitators and barriers to OESA participation. The structure and content of the OESA-EQ is informed by the four components of the ICF-CY framework: (1) The Body (Body Functions and Body Structures), (2) Activities and Participation, (3) Environmental Factors, and (4) Personal Factors. The four ICF-CY components are represented as follows. Within the OESA-EQ The Body is represented by the ability and behaviour domain, Activities and Participation are represented by levels of participation engagement and the program domain, Environmental Factors are represented by both the environmental and social domains, and Personal Factors are represented by demographic information.
Are modern metaheuristics successful in calibrating simple conceptual rainfall–runoff models?
Creators: name: Piotrowski, Adam P.
name: Napiorkowski, Maciej J.
name: Jarosław J. Napiorkowski
name: Osuch, Marzena
name: Kundzewicz, Zbigniew W.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Statistics
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Although in recent years sampling approaches have been more widely used than optimization algorithms to find parameters of conceptual rainfall–runoff models, the difficulty of calibration of such models remains disputed. The problem of finding a set of optimal parameters of conceptual rainfall–runoff models is differently interpreted in various studies, ranging from simple to relatively complex and difficult. In many papers, it is claimed that novel calibration approaches, so-called metaheuristics, outperform the older ones when applied to this task, but contradictory opinions are also plentiful. The present study aims at calibration of two simple lumped conceptual hydrological models, HBV and GR4J, by means of a large number of metaheuristic algorithms. The tests are performed on four catchments located in regions with relatively similar climatic condition, but on different continents. The comparison shows that, although parameters found may somehow differ, the performance criteria achieved with simple lumped models calibrated by various metaheuristics are very similar and differences are insignificant from the hydrological point of view. However, occasionally some algorithms find slightly better solutions than those found by vast majority of methods. This means that the problem of calibration of simple lumped HBV or GR4J models may be called deceptive from the optimization perspective, as the vast majority of algorithms that follow a common evolutionary principle of surviving the fittest lead to sub-optimal solutions.
ГИСТОМОРФОЛОГИЧЕСКАЯ СТРУКТУРА ВНУТРЕННЕЙ ОБОЛОЧКИ СУСТАВНОЙ КАПСУЛЫ КОЛЕННОГО СУСТАВА В НОРМЕ
Creators: name: Исмаилов, Ахроридин
name: Юсупов, Жахонгир
Publisher: name: Zenodo
Year: 2024

description: Одной из частых причин нетрудоспособности людей в молодом и взрослом возрасте явяется патология коленного сустава последнее время часто встречается (Павлова В.Н., Павлов Г.Г., Шостак Н.А.,2011.)
A regional water balance indicator inferred from satellite images of an Andean endorheic basin in central-western Argentina
Creators: name: Bianchi, Lucas O.
name: Rivera, Juan Antonio
name: Rojas, Facundo
name: Navarro, Mauro Britos
name: Villalba, Ricardo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: In the Central Andes of Argentina (30–37°S), snowmelt is the main source of freshwater, an essential natural resource for ~2.2 million people in the adjacent arid lowlands. In this region, Laguna Llancanelo collects the water inputs from the Malargüe endorheic basin. Previous studies concerning the annual and intra-annual variations of this lagoon and its relationship with regional climate are rare. We obtained a monthly record for the Laguna Llancanelo area (LLA, 1984–2013) using the modified normalized difference water index derived from Landsat images. Monthly LLA ranges between 35 km2 and 411 km2 and is significantly related to variations of the Río Malargüe, the main snow-fed tributary to the lagoon. There is no long-term relationship between LLA and local rainfall, but rapid increases in LLA result from heavy rainfall around the lagoon. Conversely, rapid reductions in LLA encompass periods with both reduced discharge from the Río Malargüe and low local rainfall. The LLA integrates moisture of both Pacific (snowfall in the upper Andes) and Atlantic (lowland rainfall) origins; therefore, we propose using LLA as an indicator of regional water balance.
A Romano-British quern-manufacturing site at Blackbrook, Derbyshire
Creators: name: Palfreyman, Alan
name: Ebbins, Susan
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 33-48
description: Description and discussion of a collection of quernstones found in the area around Starbuck House and Holly House in Longwalls Lane near Blackbrook, most having been recovered from or identified within drystone walls. Around thirty quernstones and fragments were examined and ascribed to the Romano-British period, the implication being that they had been made nearby as the immediate area contains evidence of quarrying. Includes
Roman finds in Chellaston, Derby - a cautionary tale
Creators: name: Butler, Mike
name: Tinkler, Pat
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 49-54
description: Note on the investigation of a possible Roman site in the garden of a house in the Chellaston area of Derby, following the discovery of various items by metal detector, including twenty-two coins, a disc brooch and two buckles. The exploratory excavation, combined with evidence from the surrounding area, led to the conclusion that the artefacts had been transported to the site from elsewhere, possibly in top soil or turf used during construction of the garden. Includes
A medieval anthropomorphic sherd from Aldwark, Brassington, Derbyshire
Creators: name: Makepeace, G A
name: Cumberpatch, Chris G
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 55-57
description: Notes on a medieval sherd depicting a bearded face, apparently from the rim of a vessel, found whilst fieldwalking in an area to the northwest of Aldwark.
Cistercian ware kiln at Ticknall: note on 2006 excavation
Creators: name: Spavold, Janet
name: Brown, Susan J
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 102-103
description: Report on the excavation of a waste tip from a previously known kiln site for the production of late medieval Cistercian wares at Church Lane, Ticknall.
Fieldwork in Derbyshire during 2005 by ARCUS (Sheffield University)
Creators: name: Arcus
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 104-113
description: Short, separately authored summaries of archaeological investigations carried out by ARCUS in Derbyshire during 2005, arranged in alphabetical order by town, parish or other location, including
Fieldwork in Derbyshire by Trent and Peak Archaeological Unit in 2004-2006
Creators: name: Tpau
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 114-138
description: Short, separately authored summaries of archaeological investigations carried out by Trent & Peak Archaeological Unit between 2004 and 2006, arranged in alphabetical order by town, parish or other location, including
The Fynderne inheritance.
Creators: name: Foster, Barbara
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 139-154
description: The author investigates the history attached to an inscription in Swarkestone Church on the tomb of Richard Harpur (d. 1577) and his wife Jane (d.1597), sister ``and heyre'' of Thomas Fynderne.
Analytical methods. Zircon and monazite geochronology of deformation in the Pielavesi Shear Zone, Finland: multistage evolution of the Archaean–Proterozoic boundary in the Fennoscandian Shield
Creators: name: Woodard, Jeremy
name: Tuisku, Pekka
name: Kärki, Aulis
name: Lahaye, Yann
name: Jarosław Majka
name: Huhma, Hannu
name: Whitehouse, Martin J.
Publisher: name: Geological Society of London
Year: 2016
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Analytical Methods
The Peak Forest canal, 1846-1926
Creators: name: Hodgkins, David
Publisher: name: Archaeology Data Service
Year: 2007

description: The Derbyshire Archaeological Journal, 127, 155-166
description: The article investigates the history of the Peak Forest Canal and its associated tramway and quarries following their lease in 1846 by the Manchester, Sheffield, and Lincolnshire Railway up until the closure of the tramway in 1926.
Increases in the Association Between the Rates of Synchronous and Metachronous Metastases over Time
Creators: name: Yilmaz, Ugur
name: Marks, Lawrence B.
name: Rowe, Steven P.
Publisher: name: MDPI
Year: 2025

description:
Background: This study investigates the association between synchronous and metachronous metastases across various cancer types, evaluating whether that relationship has evolved over time. Methods: Data from the Surveillance, Epidemiology, and End Results (SEER)-8 dataset from 1975 to 2020 were retrospectively reviewed. For each of the 18 solid tumor types, the crude rates of synchronous and metachronous metastases were estimated from the SEER database. For each of the years assessed (from 1975 to 2015 at 10-year increments), linear regression analyses were conducted to quantify the relationship between the rates of metachronous metastasis and synchronous metastasis across all cancer sites. The degrees of association over time were compared using a Fisher’s z-transformation. Results: At all time points considered, there was a significant association between the rates of metachronous and synchronous metastases (all p values < 0.05 for 5-year follow-up data). The degree of that association tended to increase over time (R = 0.59, 0.60, 0.66, 0.80, and 0.87 for 1975, 1985, 1995, 2005, and 2015, respectively), with the p value of the z-score comparing the many R values over time varying from 0.04 to 0.48. Conclusions: There appears to be an increasing association between the rates of synchronous and metachronous distant metastases over time. The exact cause of this increasing association is unknown. However, it appears to have occurred somewhat contemporaneous with the increasing use of more-accurate imaging studies (e.g., FDG-PET). Newer, targeted radiotracers for PET may provide the landscape for a prospective evaluation of the role of imaging.
Supplementary Material for: Unusual Chromosomal Rearrangement Resulted in Interstitial Monosomy 9p: Case Report
Creators: name: Durmaz, C.D.
name: Yararbaş, K.
name: Kutlay, N.Y.
name: Türedi Ö.
name: Akın İ.
name: Gürbüz, C.
name: Karataş, G.
name: Tükün, A.
Publisher: name: Karger Publishers
Year: 2016
Subjects: Medicine

description:
We report on a 4.5-year-old boy with interstitial monosomy 9p in a unique and complex de novo rearrangement. The patient had been referred for craniofacial dysmorphism, delayed psychomotor development, and various congenital malformations. We combined cytogenetic studies and FISH analyses to delineate the deletion. The result of our cytogenetic studies was 46,XY,der(9)(p22pter). In order to confirm the deletion, we also performed FISH analysis, which showed that the 9p subtelomeric region was inserted into chromosome 13. Molecular karyotyping was performed to describe the exact genomic breakpoints of the rearrangement. In conclusion, this case is a complex insertion/deletion abnormality which has not been reported before.
Plant derived anti-cancerous secondary metabolites as multipronged inhibitor of COX, Topo, and aromatase: molecular modeling and dynamics simulation analyses
Creators: name: Singh, Swati
name: Awasthi, Manika
name: Pandey, Veda P.
name: Upendra N. Dwivedi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: In the present study, 300 plant derived secondary metabolites (100 each of alkaloid, flavonoid, and terpenoid), have been screened for their anti-cancerous activity through inhibition of selected key enzymatic targets, namely cyclooxygenases (COXs), topoisomerases (Topos), and aromatase by molecular docking approach. Furthermore, the stability of the complexes of top hits, from each class of secondary metabolites, with their respective enzymatic targets was analyzed using molecular dynamics (MD) simulation analyses and binding free energy calculations. Analysis of the results of the docking in light of the pharmacokinetically screened 18 alkaloids, 26 flavonoids, and 9 terpenoids, revealed that the flavonoid, curcumin, was the most potent inhibitor for all the selected enzymatic targets. The stability of the complexes of COX-1, COX-2, Topo I, Topo IIβ and aromatase with the most potent inhibitor curcumin and those of the respective drugs, namely ibuprofen, aspirin, topotecan, etoposide, and exemestane were also analyzed through MD simulation analyses which revealed better stability of curcumin complexes than those of respective drugs. Binding energy calculations of the complexes of the curcumin with all the targets, except those of Topos, exhibited lower binding energies for the curcumin complexes than those of respective drugs which corroborated with the results of molecular docking analyses. Thus, the present study affirms the versatile and multipronged nature of curcumin, the traditionally used herbal medicine, as anti-cancer molecule directed against these enzymatic targets.
title: A Global Comparison of Communication Intervention Strategies for Justice-Involved Youth
Creators: name: Martinez, Sophia Janeiro
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2024

description: Purpose: This paper explores the intricate relationship between communication disorders and delinquent youth behavior. It will explore the detrimental impact of zero-tolerance policies and their contribution to the school-to-prison pipeline. It will introduce issues, such as complex Miranda warning diction, and the benefits of including speech-language pathologists (SLPs) to aid in youth comprehension. Additionally, it will propose the integration of SLPs within the juvenile justice system to assist in communication between justice-involved youth (JIY) and justice professionals during conversations, questioning, and trials or hearings. Furthermore, this paper examines the roles of SLPs within juvenile justice systems abroad, including Canada, the UK, New Zealand, and Australia, offering insight into adapting potential models within the US.

Method: Literature from abroad was reviewed, summarized, and condensed to provide the context for communication disorders and their link to the JIY population. This offers potential explanations as to why the prevalence of communication difficulties is high in the JIY population and possible solutions through the involvement of SLPs.

Results: Various frameworks and SLP roles within the juvenile justice system are explained, such as modifying Miranda warnings, proposing new screening and assessments on intake, explaining the role of communication intermediaries abroad, providing communication training to justice system staff led by SLPs, and integrating response-to-intervention (RTI) frameworks that include direct SLP intervention.

Conclusions: SLP involvement and the United States national attention must be given to this population. SLP advocacy was one of the driving forces for change in other countries and needs to be mirrored in the United States through the American Speech-Language-Hearing Association (ASHA) and policy reformation.
Variability in suspended sediment concentration: the effect of spatially distributed rainfall and surface erodibility, and hillslope connectivity in sediment transport
Creators: name: Battista, Giulia
name: Molnar, Peter
name: Burlando, Paolo
Publisher: name: ETH Zurich
Year: 2019

description: Geophysical Research Abstracts, 21
description: ISSN:1029-7006
description: ISSN:1607-7962
Land at Otterhole Farm, St. John;s Road, Buxton: archaeological investigations 2003
Creators: name: Cherrington, Richard
name: Jones, Laurence
Publisher: name: Archaeology Data Service
Year: 2008

description: The Derbyshire Archaeological Journal, 128, 1-18
description: Archaeological investigations of land at Otterhole Farm, St John's Road, Buxton, involving trial-trenching, test-pitting and sieving, open area excavation and metal detector survey were carried out during 2003, prior to a decision on an application for planning permission for a proposed residential development. Evidence for human activity during the prehistoric period was recorded in the form of worked flint and chert recovered during the sieving of spoil from test pits. Most of the worked flint or chert appeared to be consistent with a Late Mesolithic date with the exception of a large scraper, of possible Neolithic date. In one field a relatively high concentration of flint/chert was recorded and the test-pitting was extended to include other parts of the site. Another concentration of flint/chert was identified in the same field as the first concentration. The two concentrations suggested the existence of two potential foci of activity during the Late Mesolithic period. These two areas were hand excavated and sample sieved in order to locate any archaeological features associated with the flint/chert concentrations and to recover a larger assemblage of finds. No archaeological features were identified; however a regionally important assemblage of worked flint and chert was recovered. The tools comprised discoidal scrapers, end scrapers, serrated flakes, bladelets, retouched pieces and microliths. The technology appeared to be geared to bladelet production with crested blades, bladelet core trimming flakes and bladelet cores much in evidence. The content of the lithic assemblage suggests the presence of a Late Mesolithic (6500--3500 BC) base or winter camp used by people following a hunter--gatherer way of life. Separately authored contributions include
Resolution matters: numerical analysis of the effect of subgrid heterogeneities on soil hydrology and slope stability with a physically based hydrological model
Creators: name: Leonarduzzi, Elena
name: Maxwell, Reed M.
name: Molnar, Peter
Publisher: name: ETH Zurich
Year: 2019

description: Geophysical Research Abstracts, 21
description: ISSN:1029-7006
description: ISSN:1607-7962
An archaeological watching brief at the Old Barn, Darley Abbey, Derby
Creators: name: Shakarian, Jessika
Publisher: name: Archaeology Data Service
Year: 2008

description: The Derbyshire Archaeological Journal, 128, 53-63
description: An archaeological watching brief was undertaken during 2006--7 on the site of the Old Barn, Darley Abbey, Derby, in advance of restoration work to the nineteenth-century barn. The site was of historical interest due to the `missing' remains of the Augustinian abbey believed to have been established c. 1146. The abbey was demolished in 1538, leaving only one standing building, the Old Abbey Public House. During the watching brief three walls and a narrow path were uncovered which are believed to have been associated with the abbey. Two of the walls were substantial structural walls; the third appeared to be a smaller, internal wall. Medieval pottery was discovered beneath the foundation layer of one of the walls, confirming a mid-thirteenth- to fourteenth-century date. Whilst excavating service trenches another wall, with an associated flagged floor level, was uncovered. The stone used was comparable to that of the previous walls discovered but the structures were proven to be of a later date. A large arched structure was discovered in close proximity to the Old Abbey Public House which was believed to be a bridge located over a previous mill fleam. As a result of these discoveries it was decided that the new barn building would be moved 3m to the east, enabling all the discoveries to be preserved in situ.
Prehistoric and Roman Derby: excavations at Littleover, Derby, 2003-4
Creators: name: Martin-Bacon, H
name: Woodward, Ann
Publisher: name: Archaeology Data Service
Year: 2008

description: The Derbyshire Archaeological Journal, 128, 19-39
description: A programme of archaeological work was undertaken at Littleover, Derby, on land adjacent to the site of the former Post House Hotel, in advance of development. A desk-based assessment and geophysical survey was followed by an archaeological evaluation. An area was then targeted for excavation, together with a watching brief maintained during development groundworks. The earliest excavated features was the cremation of a juvenile, contained within a Cordoned Urn of later Early Bronze Age date. Further cremations, possibly of this date, were recorded but not excavated. Also recorded was a line of pits, tentatively interpreted as part of a pit alignment. A length of Roman road, Ryknield Street, surfaced with gravel and flanked by drainage ditches, was also recorded. Separately authored contributions include
Effects of Flow Regulation on the Surface Water-Groundwater System in an alpine gravel-bed braided River (Maggia)
Creators: name: Bergami, Gianluca
name: Molnar, Peter
name: Burlando, Paolo
Publisher: name: ETH Zurich
Year: 2019

description: Geophysical Research Abstracts, 21
description: ISSN:1029-7006
description: ISSN:1607-7962
An archaeological evaluation on Alfreton Road, Little Chester, Derby
Creators: name: Tate, John
name: Cooper, Nicholas J
name: Johnson, Elizabeth
Publisher: name: Archaeology Data Service
Year: 2008

description: The Derbyshire Archaeological Journal, 128, 40-52
description: An archaeological evaluation, undertaken in advance of housing development at the former Bristol Street Motors on Alfreton Road, Little Chester, detected evidence for the Roman period extramural settlement relating to the adjacent fort. A mid-first-century ditch, together with second-century features containing charcoal and daub, probably deriving from the destruction of timber structures, were recorded and probably relate specifically to the rear of plots fronting onto the north side of the Old Chester Road. Separately authored contributions include
Fieldwork carried out bv Archaeological Project Services in Derbyshire in 2006
Creators: name: Taylor, Gary
Publisher: name: Archaeology Data Service
Year: 2008

description: The Derbyshire Archaeological Journal, 128, 64-64
description: Brief, separately authored notes on fieldwork carried out at Scallywags Nursery, Castle Lane, Melbourne, and on the course of the River Trent Left Bank Flood Alleviation Scheme, Sawley--Long Eaton.
title: 02_1620
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Electron microprobe analyses. Earliest microbial trace fossils in Archaean pillow lavas under scrutiny: new micro-X-ray absorption near-edge spectroscopy, metamorphic and morphological constraints
Creators: name: Grosch, Eugene G.
name: Muñoz, Manuel
name: Mathon, Olivier
name: McLoughlin, Nicola
Publisher: name: Geological Society of London
Year: 2016
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Representative electron microprobe analyses of retrograde minerals in the BG-173 metabasaltic assemblage and the local rock composition calculated from the electron microprobe map compositions using XMapTools
The impact of deforestation on the hydrological cycle in Amazonia as observed from remote sensing
Creators: name: Vergopolan, Noemi
name: Fisher, Joshua B.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology
subject: Computational Biology

description: Given widespread Amazonian deforestation, numerous studies have focused on how the regional hydrological cycle – in terms of precipitation (P) recycling from evapotranspiration (ET) – is impacted by deforestation. Nevertheless, climate macroscale and mesoscale models have given contradictory results on changes in ET and P with deforestation. To date, these results have not been evaluated with observations, so in this work, we assessed a decade of patterns in ET and P over deforested and forest areas using remote sensing (MODIS and TRMM, 2000–2012). We found a relative increase in ET and P in deforested areas, though there was a positive ET and P correlation over southern/deforested, and negative in northern/forested Amazonia. Although the absolute ET and P values are lower in deforested areas in comparison to border areas, we observed a positive change in ET and P in the last 10 years at the deforested areas. The increase in ET was larger within the deforested areas; meanwhile, P increased more from inside forest areas to the borders, which agrees with the ET and P correlation patterns. Our results help to inform the debate between the macroscale and mesoscale models, as deforestation impacts small-scale circulation patterns, turbulence, and moisture fluxes and convergence, and expand our understanding of the processes involved.
µXANES spectra and corresponding fitted pre-edge peaks. Earliest microbial trace fossils in Archaean pillow lavas under scrutiny: new micro-X-ray absorption near-edge spectroscopy, metamorphic and morphological constraints
Creators: name: Grosch, Eugene G.
name: Muñoz, Manuel
name: Mathon, Olivier
name: McLoughlin, Nicola
Publisher: name: Geological Society of London
Year: 2016
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Representative µXANES spectra and corresponding fitted pre-edge peaks for all spot analyses along line scan 1 (cf. Fig. 3 main paper for map position)
Guest beds and stabling in Derbyshire, 1686-1756
Creators: name: Riden, Philip
Publisher: name: Archaeology Data Service
Year: 2008

description: The Derbyshire Archaeological Journal, 128, 65-98
description: The paper analyses the evidence provided by three lists of `guest beds' (places available for billeting private soldiers) and stalls for horses, indicating the number and distribution of inns and alehouses in Derbyshire in the late-seventeenth and early-eighteenth centuries. Includes
Implementation of digital interventions in psychosis and schizophrenia: A scoping review
Creators: name: Beckwith, Helen
name: Jenner, Lucy
name: Waite, Felicity
name: Freeman, Daniel
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Psychiatry and Psychology
subject: Medicine and Health Sciences

description: The aim of this review is to learn from published successful and unsuccessful implementation strategies of digital interventions relevant to the care and treatment of psychosis and schizophrenia.
We will conduct this review alongside preparation of a 6-month online guided program for persecutory delusions (Treating persecutory delusions successfully: enabling patients with psychosis to receive the most effective psychological therapy - NIHR Funding and Awards).
We intend to summarise what has been done and learnt in order to inform implementation of future digital interventions with this population.
The Midland Counties Railway basin and coke store at Long Eaton
Creators: name: Mitchell, Ian
Publisher: name: Archaeology Data Service
Year: 2008

description: The Derbyshire Archaeological Journal, 128, 99-122
description: Account of the history, site description and discussion of the canal basin, house and coke store on the Erewash Canal consructed in 1840 to service the Midland Counties Railway at the point where it crossed the canal in Long Eaton. Includes
Soil carbon research and global environmental challenges
Creators: name: Hartemink, Alfred E.
name: Lal, Rattan
name: Gerzabek, Martin H.
name: Jama, Bashir
name: McBratney, Alex
name: Six, Johan
name: Tornquist, Carlos G.
Publisher: name: ETH Zurich
Year: 2014
Subjects: Soil carbon
Environment
Research priorities

description: The role of soil organic carbon (SOC) in maintaining soil conditions and its resulting services is well established. Currently, over 1,000 articles per year are being published in peer-reviewed journals, and increasing at about 10% per year. It was not until the 1980s when the relation between soils and climate change was noted, and it was realized that soils play a key role as a sink and source of greenhouse gases (GHGs) ( Bouwman 1990, Scharpenseel, Ayoub and Schomaker 1990, Jenny 1980). A large number of research projects have been initiated globally in which soil C is a key component, and there have been some excellent reviews ( Lal 2004, Stockmann et al. 2013, Melillo et al. 2011). Yet, there is a lack of focus in soil C research in relation to current environmental challenges. Here we recommend research priorities to advance the knowledge base and use of soil C in relation to global human and environmental challenges: food and fiber production, water scarcity and purification, energy production, climate change, biodiversity, recycling waste, and environmental degradation. We have listed the priorities under three themes: (i) Soil C in space and time, (ii) Soil C properties and processes, and (ii) Soil C depletion and management.
description: PeerJ Preprints, 2
description: ISSN:2167-9843
Engineering Integrated Care Expansion and Innovation: Drawing upon Nursing Leadership
Creators: name: Weber, Mary
name: Barton, Amy J.
name: Delaney, Kathleen R.
name: Emerson, Margaret R.
name: Soltis-Jarrett, Victoria
Publisher: name: MDPI
Year: 2025

description:
In the United States (US), a longstanding solution to the unmet need for mental health treatment is integrated behavioral health care (IBH). Within a primary care model, problems are identified and treatment combines care for physical, mental and substance use disorders. Treatments are delivered through the collaboration of primary and behavioral health providers. According to US federal billing guidelines, in one integrated model, the Collaborative Care Model (CoCM), the psychiatric consultant must be a medical professional trained in psychiatry and capable of prescribing medications, i.e., either a psychiatrist, Psychiatric Mental Health Nurse Practitioner (PMHNP) or Physician Assistant. The development of integrated care has been slow for particular vulnerable populations, in part due to the lack of psychiatric consultants. PMHNPs are increasingly taking on the role of psychiatric consultants on CoCM teams and creating nurse-led IBH models for underserved populations. In this paper, eight such models are discussed along with implementation challenges and the strategies used to address them. Nurse leaders have the capacity to enhance and expand integrated care, particularly for underserved populations, through the optimal utilization of care teams, expanding measured outcomes, and developing measures for team-based effectiveness. Future directions are proposed that will accelerate this PMHNP-led expansion of IBH.
Island Visits : Neolithic & Bronze Age activity on the Trent Valley floor. Excavations at Eggington & Willington, Derbyshire. 1998-1999.
Creators: name: Beamish, Matthew G
Publisher: name: Archaeology Data Service
Year: 2013

description: The Derbyshire Archaeological Journal, 129, 17-172
description: Excavations at Willington sand and gravel quarry between 1998 and 1999 have produced evidence of prehistoric activity on the floodplain within the Middle Trent Valley. Areas of low wooded islands surrounded by active streams were a focus of Early to Middle Neolithic activity. Peterborough wares were the predominant pottery. Non-animal foodstuffs were predominantly wild, but there was also evidence of dairying. There is evidence of fire clearance that was repeated over several centuries from the later half of third millennium cal BC. A burnt mound was probably used as a seasonal cooking site over a number of years. The area then appears to have been abandoned, and was used as a burial mound in the later Early Bronze Age: a small ring ditch encircled a grave cut into alluvial silts. In the late second millennium ca BC, there is renewed seasonal burnt mound activity in a partly wooded landscape near a stream. The waterlogged remains are of outstanding quality, including a rectangular roundwood-lined trough.