cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mus monax Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Muridae
Mus
Mus monax

description: Mus monax [spec. nov.]
M cauda mediocri pilosa, corpore griseo, auriculis subrotundis, palmis tetradactylis, plantis pentadactylis.
Monax s. Marmota americana. Edv. av. 104. t. 104.
Habitat in America septentrionali.
Auriculae subrotundae.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 60, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Modelling the contribution of hormonal and inflammatory pathways to term and preterm labour in the mouse
Creators: name: Migale, Roberta
Publisher: name: Imperial College London
Year: 2016

description: Labour onset results from a complex interplay between hormonal and inflammatory signals. Untimely activation of these pathways can cause preterm labour (PTL) and premature birth (<37 weeks of gestation), the primary cause of infant mortality. Throughout gestation, uterine quiescence is maintained by progesterone and its withdrawal at term induces pro-labour genes and activation of uterine contractions. Infection and inflammation are frequently associated with PTL. Recognition of bacteria by the maternal innate immune system involves activation of nuclear factor kappa-B (NFκB) and activator protein-1 (AP-1), which regulate inflammatory and pro-labour genes. The aim of this thesis was to determine the contribution of inflammatory and hormonal pathways to parturition in murine models by comparing molecular changes in myometrium throughout term gestation, PTL induced by lipopolysaccharide (LPS; inflammation-induced PTL), and RU486-induced PTL by progesterone withdrawal (non-inflammatory PTL). Term gestation was shown to involve sequential activation of NFκB and AP-1. Different LPS serotypes induced heterogeneous maternal and fetal responses in the LPS-induced PTL model. LPS O111:B4 caused the most severe phenotype of PTL within 7h and total fetal demise. This involved JNK/AP-1-mediated activation of uterine inflammation, without NFκB activation. TLR-4 ablation rescued this phenotype and JNK inhibition delayed PTL. RU486 caused PTL without modulation of inflammatory pathways. RNA-Seq was used to characterize dynamic uterine transcriptome changes antecedent to term labour or PTL (RU486 or LPS-induced). Strong similarity was observed within term gestation and RU486-induced PTL transcriptomes, while the LPS model involved distinctive inflammatory gene changes. Positive correlation was found between human and murine transcriptomes. This thesis shows that LPS-induced inflammation can override repressive effects of progesterone on pro-labour genes while abrogation of progesterone signalling prompts PTL without inflammatory gene activation. These data support the paradigm of a common terminal pathway of labour yet provides new evidence that inflammatory gene activation is not necessary for labour.
Additional file 1 of Increased Wnt/β-catenin signaling contributes to autophagy inhibition resulting from a dietary magnesium deficiency in injury-induced osteoarthritis
Creators: name: Bai, Ruijun
name: Miao, Michael Z.
name: Li, Hui
name: Wang, Yiqing
name: Hou, Ruixue
name: He, Ke
name: Wu, Xuan
name: Jin, Hongyu
name: Zeng, Chao
name: Cui, Yang
name: Lei, Guanghua
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Science Policy
subject: Developmental Biology

description: Additional file 1: Supplemental Figure 1. Body weight of mice over time. Body weight of sham and DMM-induced OA mice fed with diets containing different content of magnesium (500 mg/kg, 300 mg/kg, 100 mg/kg) measured weekly. No statistical significance was observed between different groups at the same age.
Mus cricetus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Muridae
Mus
Mus cricetus

description: Mus cricetus [spec. nov.]
M. cauda subabbreviata, auriculis rotundatis, corpore subtus nigro, lateribus rufescentibus.
Mus cauda elongata, corpore cinereo rutilo nigroque longitudinaliter vario. Syst. nat. 10. n. 10.
Cricetus. Raj. quadr. 221. E. N. C. d. 2. a. 5. obs. 186. Gesn. quadr. 738.
Hamster. Meijer. thier. (Norib. 1748. fol.) t. 81. 82.
Habitat in Germania.
Numerus digitorum pedum in hac & antecedente nobis ignotus. Cuniculo minor, cauda pedibus fere brevior. Bucca utrinque saccata.
Cavernas fodit sub terra plurimis concamerationibus, duplici foramine: altero obliquo aditu, altero perpendiculari specula. Colligit Frumentum, Pisa, Fabas, fructus, in distinctis cameris servanda, adportat ea in bucca; parit bis in anno sex pullos, itidem in propria camera servandos, uti etiam sterquilinium in distincta.
Venatur ob carnes, pelles, frumentum collectum; occiditur pulvere Veratri, farina & melle in panes coctis.
Citillus auctorum, si ab hoc diversus, probe observandus.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on pages 60-61, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Additional file 2: of The gut of the finch: uniqueness of the gut microbiome of the GalĂĄpagos vampire finch
Creators: name: Michel, Alice
name: Ward, Lewis
name: Goffredi, Shana
name: Dawson, Katherine
name: Baldassarre, Daniel
name: Brenner, Alec
name: Gotanda, Kiyoko
name: McCormack, John
name: Mullin, Sean
name: OâNeill, Ariel
name: Tender, Gabrielle
name: J. Uy
name: Yu, Kristie
name: Orphan, Victoria
name: Chaves, Jaime
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry

description: Table S2. Microbiome diversity averages for all finch species measured in this study, along with sample sizes and diet category. Data is based on 16S rRNA gene OTU clustering at 97% identity trimmed to at least 1% relative abundance in at least one finch. (DOCX 71 kb)
Dynamic extended finite element method (XFEM) analysis of discontinuous media
Creators: name: Toolabi, Milad
Publisher: name: Imperial College London
Year: 2015

description: The extended finite element method (XFEM) is found promising in approximating solutions to locally non-smooth features such as jumps, kinks, high gradients, inclusions, or cracks in solid mechanics problems. The XFEM uses the properties of the partition of unity finite element method (PUFEM) to represent the discontinuities without the corresponding finite element mesh requirements. In the present thesis numerical simulations of statically and dynamically loaded heterogeneous beams, heterogeneous plates and two-dimensional cracked media of isotropic and orthotropic constitutive behaviour are performed using XFEM. The examples are chosen such that they represent strong and weak discontinuities, static and dynamic loading conditions, anisotropy and isotropy and strain-rate dependent and independent behaviours. At first, the Timoshenko beam element is studied by adopting the Hellinger-Reissner (HR) functional with the out-of-plane displacement and through-thickness shear strain as degrees of freedom. Heterogeneous beams are considered and the mixed formulation has been combined with XFEM thus mixed enrichment functions are used. The results from the proposed mixed formulation of XFEM correlate well with analytical solutions and Finite Element Method (FEM) and show higher rates of convergence. Thus the proposed method is shear-locking free and computationally more efficient compared to its conventional counterparts. The study is then extended to a heterogeneous Mindlin-Reissner plate with out-of-plane shear assumed constant through length of the element and with a quadratic distribution through the thickness. In all cases the zero shear on traction-free surfaces at the top and bottom are satisfied. These cases involve weak discontinuity. Then a two-dimensional orthotropic medium with an edge crack is considered and the static and dynamic J-integrals and stress intensity factors (SIF’s) are calculated. This is achieved by fully (reproducing elements) or partially (blending elements) enriching the elements in the vicinity of the crack tip or body. The enrichment type is restricted to extrinsic mesh-based topological local enrichment in the current work. A constitutive model for strain-rate dependent moduli and Poisson ratios (viscoelasticity) is formulated. The same problem is studied using the viscoelastic constitutive material model implemented in ABAQUS through an implicit user defined material subroutine (UMAT). The results from XFEM correlate well with those of the finite element method (FEM). It is shown that there is an increase in the value of maximum J-integral when the material exhibits strain rate sensitivity.
Experimental evaluation of steady and pulsating flow performance of an asymmetric double entry turbine for an automotive turbocharger
Creators: name: Gurunathan, Balamurugan A
Publisher: name: Imperial College London
Year: 2016

description: Variable Geometry Turbines are widely used in High Pressure Loop Exhaust Gas Recirculation to enhance positive pressure gradient between turbine inlet and compressor outlet. Multiple-entry turbines (twin or double) can achieve an enhanced pulse energy extraction when compared with single entry devices. However, when EGR takes place, an imbalance of mass flow can lead to significant energy loss. This thesis presents the design and experimental assessment of a novel asymmetric double entry turbine that aims to achieve pulse energy recovery even in the face of high EGR. The asymmetric double entry volute was developed with two different scroll lengths: a small scroll that feeds the rotor between azimuth angle of 0° and 160°, beyond which rotor is fed by the large scroll. A pivoting action is designed to enable an optimisation of the optimum angle in each scroll sector. Extensive testing was carried out to characterise the novel turbine under various steady and unsteady flow conditions (full, partial, unequal, in phase and out of phase). The peak recorded efficiency for the full admission nozzleless condition was found to be 78%. When nozzle was present in the small scroll, the efficiency had a similar magnitude (77.6%); while when nozzles were present in both scrolls a lower efficiency was found (74.4%). Considering nozzles only on the small sector: as the vane angle opening changes from most open position (51°) to mid open position (71°) an increase in stage efficiency was observed. Under partial admission, the nozzleless unit showed a very significant the deficit in peak efficiency: 17 points with large scroll flowing and 25 points with small scroll flowing. When nozzle vanes are introduced in the small scroll sector a similar drop was found; but when vanes were present in both scrolls the deficit during partial reduced (13.9% for the best performing configuration). During unequal admission the nozzleless and small nozzle setting displayed a symmetrical efficiency characteristic. During unsteady flow admission at 30k RPM for all frequencies showed that the nozzle configurations recorded higher cycle average efficiency than the base line nozzleless unit. Test results at 20 Hz and 40 Hz have shown higher cycle average efficiency than 60 Hz. Interestingly when nozzles were present on both scrolls the cycle average efficiency increased by almost 13 percentage point higher than nozzleless indicating the value of introducing nozzles.
The role of miRNA deregulation in non-genotoxic chemical induced carcinogenesis
Creators: name: Flores Torres, Mariana
Publisher: name: Imperial College London
Year: 2015

description: MicroRNAs (miRNAs) are short, non-protein coding RNAs. These small-RNAs can regulate gene expression by either inhibiting translation or promoting mRNA degradation, they are also involved in diverse physiological and pathological events. Previous data from our group, showed that phenobarbital (PB, a CAR activator), induces dysregulation of the hepatic miRNAome in rat livers. In this study, we aim to determine if non-genotoxic rodent carcinogens can deregulate miRNA expression. Thus, the liver miRNAome associated with a novel chemical (SYN) and the non-genotoxic rodent carcinogen PB was explored at different doses and time points using high-throughput sequencing of small-RNAs (miRNA seq), a powerful tool for discovery and profiling of miRNA expression, providing a deeper understanding of molecular toxicology. Male Han Wistar rats were treated with PB (50 or 1000 ppm) or SYN (50, 500, and 3000 ppm) in the diet for up to 28 days. Control animals were fed regular diet. Rats were sacrificed after 1, 3, and 28 days. Total RNA was isolated from frozen livers and library constructs were generated with the Illumina platform. The miRanalyzer algorithm and DESeq were used for bioinformatics (for known and novel miRNAs) and statistical analysis. Around 200 known miRNAs were detected per sample. Three key miRNAs related to the epithelial-to-mesenchymal transition (EMT), were detected at the 3rd day –miR-200s, miR 30b, and miR-21. Consequently downregulation of targets related to these RNAs and EMT (ZEB1/2, Snail-1, PTEN, and E-cadherin) was seen. These findings suggest activation of a homeostatic response in EMT control in response to PB/SYN treatment, presumably in order to preserve the epithelial nature of hepatocytes. Analysis of putative novel miRNAs sequences determined three candidates homologous to miR-4488 and a putative isomiRNA of miR-6215. The miRNA-seq approach enables a more detailed exploration of miRNAs and their response to hepatotoxicants, such as PB, helping elucidate underlying pathway perturbations.
The large D Membrane Paradigm For Einstein-Gauss-Bonnet Gravity
Creators: name: Saha, Arunabha
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We find the equations of motion of membranes dual to the black holes in Einstein-Gauss-Bonnet (EGB) gravity to leading order in 1/D in the large D regime. We also find the metric solutions to the EGB equations to first subleading order in 1/D in terms of membrane variables. We propose a world volume stress tensor for the membrane whose conservation equations are equivalent to the leading order membrane equations. We also work out the light quasi-normal mode spectrum of static black holes in EGB gravity from the linearised fluctuations of static, round membranes. Also, the effective equations for stationary black holes and the spectrum of linearised spectrum about black string configurations has been obtained using the membrane equation for EGB gravity.All our results are worked out to linear order in the Gauss-Bonnet parameter.
description: Two new sections on stationary membranes and black branes added. Abstract modified to take care of changes. Some typos corrected
Mus terrestris Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Muridae
Mus
Mus terrestris

description: Mus terrestris [spec. nov.]
M. cauda mediocri subpilosa, palmis subtetradactylis, plantis pentadactylis, auriculis vellere brevioribus.
Mus cauda longissima pilosa, auribus subrotundis vellere brevioribus. Fn. svec. 29. Syst. nat. 10. n. 5.
Mus agrestis, capite grandi, brachiuros. Raj. quadr. 218.
Habitat in Europae terra & aqua.
Corpus fuscum subtus pallidum, at non albicans. Caput crassius, ore gibbo. Cauda magis pilosa, quam in Ratto, sed corpore dimidio brevior, a pedibus fere longior.
Hortos Talpae instar misere effodit palmis licet parvis; natat in fossis & urinatur plantis licet fissis; Radices arborum decorticat, plantarum consumit s. aufert; Pullos anatum in piscinis occidit.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 61, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Production of Milky Way structure by the Magellanic Clouds
Creators: name: Weinberg, Martin D.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Previous attempts at disturbing the galactic disk by the Magellanic Clouds relied on direct tidal forcing. However, by allowing the halo to actively respond rather than remain a rigid contributor to the rotation curve, the Clouds may produce a wake in the halo which then distorts the disk. Recent work reported here suggests that the Magellanic Clouds use this mechanism to produce disk distortions sufficient to account for both the radial location, position angle and sign of the HI warp and observed anomalies in stellar kinematics towards the galactic anticenter and LSR motion.
description: 8 pages, uuencoded compressed PostScript, no figures, html version with figures and mpeg simulations available at http://www-astro.phast.umass.edu/Preprints/martin/martin1/lmc_online.html
Integration of multiple environmental stresses for compound gene regulation in Arabidopsis thaliana
Creators: name: Lee, Sang Yun
Publisher: name: Imperial College London
Year: 2015

description: Plants are known to respond to various types of environmental stresses arising from physicochemical changes and other organisms. As plants often simultaneously experience multiple stress factors due to their immobility, capacity to appropriately regulate gene expression by integrating multiple stress signals is crucial for successful adaptation to hostile environments. Although significant progress has been made in elucidating the molecular mechanisms for regulation of stress response genes under single stress, little is known about the effects of combined stress signals on gene regulation and their associated mechanisms. This thesis aimed to contribute to the understanding of plant stress response by studying the signal integration mechanisms under various perspectives: first, the thesis explored how multiple stress signals affect the choices over discretised regulatory outcomes, such as up-regulation or down-regulation. We propose that processing of multiple signals can be described as logical operations, and subsequently investigate the mechanisms for each signal integration outcome by constructing logical model of intracellular signalling network. The resulting insight was applied to analyse a transcriptomic dataset from the model plant Arabidopsis thaliana, leading to novel hypotheses about potential crosstalk interactions that are missing between multiple stress signalling pathways. In parallel, the thesis also explored the cases where integration of multiple stress signals modulates dynamics of gene expression. An experimental study of the expression profile of Response-to-Dehydration 29A (RD29A), a model stress response gene, was conducted to show that combination of multiple stress inputs introduces a unique qualitative effect on dynamics of gene expression. The origin of this behaviour was investigated via a dynamical model of the RD29A regulatory network, which subsequently revealed potential interactions in the regulatory network that are currently unknown. Taken together, this thesis argues that systematic comparison between gene regulatory outcomes under single and combined stress inputs provides a crucial source of information for discovering functionally significant regulatory interactions in the stress signalling network.
Engineered scaffolds for the preservation of gliding tissue interfaces
Creators: name: Harrison, Rachael
Publisher: name: Imperial College London
Year: 2016

description: The production of modular scaffolds that allow for the facile spatial localisation of a variety of interchangeable functional groups gives a toolbox of options for tissue engineering. Furthermore, the need to re-engineer a system for each specific application or function is eliminated. A modular scaffold system based on the versatility of the electrospinning processing technique, chemical modification of bioresorbable poly-ε-caprolactone (PCL) and a controlled free radical polymerization technique is proposed. An antifouling surface is prepared by grafting a poly(oligoethylene glycol) bottlebrush (pOEGMA) from a surface initiating group on silicon wafers and electrospun PCL scaffolds. The surface initiated polymerization method provides versatility which allows for wide variety of monomer units to be selected for bespoke scaffolds and tailored to particular applications, including fluorescent labelling. The antifouling ability of the pOEGMA functionalization is explored and characterised with protein and cell assays. The chemical and mechanical stability of the pOEGMA functionalized scaffolds is explored in a simulated physiological environment over 10 weeks. Following which the chemical and material properties are re-characterised and found to be maintained. A dual functional bilayer scaffold with an antifouling, non-cell adhesive surface and an opposing cell-adhesive surface is then produced. The pOEGMA coating provides the antifouling surface whilst the cell adhesive side is prepared by end-functionalizing the PCL with the cyclic cell binding Arg-Gly-Asp-Ser (RGDS) peptide. Spatial control of the functionality through the mat is achieved by sequential electrospinning of the functionalized polymers. The opposing properties of the surfaces are demonstrated through cell culture and florescent labelling to illustrate clear spatial segregation. Gliding surfaces such as those found in the musculoskeletal systems, the tendon for example, are vulnerable to tethering from scarring following surgical and traumatic injury. This scaffold could offer protection from these scars through the control of cellular migration and may lead to improved patient outcomes.
Graphene based plasmonic photodetection
Creators: name: Shautsova, Viktoryia
Publisher: name: Imperial College London
Year: 2017

description: Graphene is a promising material for novel photonic devices due to its broadband optical absorption, ultrafast carrier dynamics and electrical tunability. However, the quantum efficiency of graphene devices is intrinsically limited by low absorption of graphene (2.3% of normal incident light). To enhance light-matter interaction, optical focusing elements such as plasmonic metal nanoparticles (NPs) can be utilized. This thesis examines the interaction between graphene and plasmonic NPs with special emphasis on mechanisms of enhanced photocarrier generation, which is further applied to improve photodection efficiency of graphene plasmonic hybrid devices. In order to study graphene based devices, CVD graphene must first be transferred from the Cu growth substrate to a target substrate. To this end, various parameters of a transfer technique were studied focusing on the source of extrinsic doping. Next, a novel transfer process based on an hBN spacer layer between graphene and a polymethyl-methacryalate film was developed to facilitate large scale CVD graphene transfer and encapsulation. The demonstrated devices showed improved electrical and aging properties. Following successful demonstration of the transfer technique, graphene was combined with gold NPs to study structural and optical properties of these complexes. Using ultrafast measurements, carrier dynamics of the hybrid structures were analysed focusing on hot carrier generation under plasmon excitation. Based on the observed results, hot carrier generation in the graphene was attributed to direct photoexcitation through the intense plasmonic electromagnetic fields with a minimal contribution from charge transfer over the graphene/NP interface. Furthermore, highly localised carrier heating in graphene is anticipated to result in strong electronic temperature gradients. Asymmetric plasmon-nanobar electrical contacts were designed with a view to exploit plasmon-induced electronic temperature gradients via the thermoelectric effect. The findings of this work lead to improved knowledge of the internal graphene photodetection mechanisms as well as contributing to the understanding of graphene/plasmonic hybrids and their interactions.
Distribution of Gamma-Ray Bursts in Halo Neutron Star-Comet Models
Creators: name: Higgins, M. G.
name: Henriksen, R. N.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The motions of comets and neutron stars have been integrated over five billion years in the Galactic potential to determine a gamma-ray burst distribution, presuming that bursts are the result of interactions between these two families of objects. The comets originate in two distinct populations - one from ejection by stars in the Galactic disk, and the other from ejection by stars in globular clusters. No choice of the free parameters resulted in agreement with both the isotropy data and the $\log(N>F) - \log(F)$ data.
description: 4 pages LaTex and two style files, tarred, compressed, and uuencoded. One postscript figure. To appear in Astrophysics and Space Science as part of the proceedings of the 29th ESLAB Symposium 'Toward the Source of Gamma-Ray Bursts' held in Noordwijk, 1995. A postscript version can be found at http://astro.queensu.ca/~mark/preprints.html
Electron and hole spin relaxation in InP-based self-assembled quantum dots emitting at telecom wavelengths
Creators: name: Mikhailov, A. V.
name: Belykh, V. V.
name: Yakovlev, D. R.
name: Grigoryev, P. S.
name: Reithmaier, J. P.
name: Benyoucef, M.
name: Bayer, M.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the electron and hole spin relaxation in an ensemble of self-assembled InAs/In$_{0.53}$Al$_{0.24}$Ga$_{0.23}$As/InP quantum dots with emission wavelengths around $1.5$~$μ$m by pump-probe Faraday rotation spectroscopy. Electron spin dephasing due to the randomly oriented nuclear Overhauser fields is observed. At low temperatures we find a sub-microsecond longitudinal electron spin relaxation time $T_1$ which unexpectedly strongly depends on temperature. At high temperatures the electron spin relaxation time is limited by optical phonon scattering through spin-orbit interaction decreasing down to $0.1$~ns at 260~K. We show that the hole spin relaxation is activated much more effectively by a temperature increase compared to the electrons.
description: 7 pages, 3 figures
Additional file 1 of MicroRNA-221-3p is related to survival and promotes tumour progression in pancreatic cancer: a comprehensive study on functions and clinicopathological value
Creators: name: Wu, Xuejiao
name: Huang, Jia
name: Yang, Zilin
name: Zhu, Ying
name: Zhang, Yongping
name: Wang, Jiancheng
name: Yao, Weiyan
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Hematology

description: Additional file 1: Figure S1. Flow chart for present research including bioinformatics data gathering, an integrated meta-analysis, and some cell functional assays. Figure S2. Overexpression of miR-221-3p facilitated the migration ability of PC cells. Figure S3. Overexpression of miR-221-3p promotes cell migrate ability in pancreatic cancer. Figure S4. Overexpression of miR-221-3p promotes invasion ability in PC cells. Table S1 Characteristics of the selected GEO data. Table S2 Relationship between clinical features of pancreatic ductal adenocarcinoma and the miR-221-3p content within TCGA dataset. Table S3 Relationship between clinical features of other types of pancreatic adenocarcinoma and the miR-221-3p content within TCGA dataset. Table S4 Relationship between clinical features of pancreatic ductal adenocarcinoma and the miR-221-3p content within RT-qPCR data. Table S5 Specific targets obtained from former articles. Table S6 Sequences of primers, miRNA mimic and inhibitor.
Additional file 1: of Aging and sex affect soluble alpha klotho levels in bonobos and chimpanzees
Creators: name: V. Behringer
name: J. Stevens
name: T. Deschner
name: R. Sonnweber
name: G. Hohmann
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Additonal assay valdiation steps. (DOCX 128 kb)
Full Optical Fiber Link Characterization with the BSS-Lasso
Creators: name: Saavedra, Raphael
name: Tovar, Pedro
name: Amaral, Gustavo C.
name: Fanzeres, Bruno
Publisher: name: arXiv
Year: 2018
Subjects: subject: Signal Processing (eess.SP)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Physical sciences

description: Manipulation of the detected backscattered Rayleigh signal inside the bandwidth of a frequency-swept optical sub-carrier propagating into an optical fiber permits an efficient localization of faults through a Fourier operator. When the bandwidth is restricted, analysis in the frequency domain can overcome the spatial resolution limitation while also inducing a high-dimensional problem. Introducing the Lasso as a signal processing technique paired with the Baseband Subcarrier Sweep (BSS) framework allows for a methodology to consistently evaluate fiber defects. In this work, a novel technique for optical fiber monitoring within the BSS framework, hereinafter called the BSS-Lasso, is proposed and tested in simulated and real-world environments, taking into account both reflective and non-reflective events. The results show that, for fiber links ranging from 2 to 15 km with up to 3 faults, over 80% of faults are detected within a 50 m range, and indicate that the proposed methodology significantly outperforms current state-of-the-art BSS-based supervision techniques. Finally, the BSS-Lasso allows for precise, low-cost, transmitter-embedded full characterization of optical fiber links.
description: IEEE Transactions on Instrumentation and Measurement, 21 Dec. 2018
Large Language Models for Synthetic Tabular Health Data: A Benchmark Study
Creators: name: Miletic, Marko
name: Sariyar, Murat
Publisher: name: IOS Press
Year: 2024
Subjects: GAN
Synthetic data generation
large language models
tabular data

description: Synthetic tabular health data plays a crucial role in healthcare research, addressing privacy regulations and the scarcity of publicly available datasets. This is essential for diagnostic and treatment advancements. Among the most promising models are transformer-based Large Language Models (LLMs) and Generative Adversarial Networks (GANs). In this paper, we compare LLM models of the Pythia LLM Scaling Suite with varying model sizes ranging from 14M to 1B, against a reference GAN model (CTGAN). The generated synthetic data are used to train random forest estimators for classification tasks to make predictions on the real-world data. Our findings indicate that as the number of parameters increases, LLM models outperform the reference GAN model. Even the smallest 14M parameter models perform comparably to GANs. Moreover, we observe a positive correlation between the size of the training dataset and model performance. We discuss implications, challenges, and considerations for the real-world usage of LLM models for synthetic tabular data generation.
A New Acoustic Emission Sensor Based Gear Fault Detection Approach
Creators: name: Qu, Yongzhi
name: Bechhoefer, Eric
name: He, David
name: Zhu, Junda
Publisher: name: University of Illinois at Chicago
Year: 2021
Subjects: Uncategorized

description: In order to reduce wind energy costs, prognostics and health management (PHM) of wind turbine is needed to reduce operations and maintenance cost of wind turbines. The major cost on wind turbine repairs is due to gearbox failure. Therefore, developing effective gearbox fault detection tools is important in the PHM of wind turbine. PHM system allows less costly maintenance because it can inform operators of needed repairs before a fault causes collateral damage happens to the gearbox. In this paper, a new acoustic emission (AE) sensor based gear fault detection approach is presented. This approach combines a heterodyne based frequency reduction technique with time synchronous average (TSA) and spectral kurtosis (SK) toprocess AE sensor signals and extract features as condition indictors for gear fault detection. Heterodyne techniques commonly used in communication are used to preprocess the AE signals before sampling. By heterodyning, the AE signal frequency is down shifted from MHz to below 50 kHz. This reduced AE signal sampling rate is comparable to that of vibration signals. The presented approach is validated using seeded gear tooth crack fault tests on a notational split torque gearbox. The approach presented in this paper is physics based and the validation results have showed that it could effectively detect the gear faults.
Museumsgeschichte in Kassel
Creators: name: Joachimides, Alexis
name: Knop, Linda
name: Jokiel, Jennifer
name: Maus, Annika
name: Timaeus, Pia
name: Kruggel, Annemarie
name: Urspruch, Melanie
name: Otto, Cathrin
name: Pein, Marcia
name: Allnoch, Julia
name: Köllner, Sabine
name: Günzel, Ann-Charlotte
name: Henning, Angelina
name: Becker, Melanie
name: Vehling, Nadine
name: Dittmar, Lena
name: Graceva, Veronika
name: Busse, Laila-Marie
name: Wurz, Johanna
name: Bonfig, Vanessa
name: Emde, Stefanie
name: Mandryka, Natalia
name: Bischoff, Julia
name: Ertas, Funda
name: Konay, Tugce
name: Schukis, Svetlana
name: Thöne, Nicole
name: Wiczkowska, Katarzyna
name: Büchner, Theresa
name: Meier, Saskia
name: Peter, Johannes
name: Schwarz, Yannick Philipp
name: Becker, Lea
name: Harder, Stephanie
name: Glaser, Marian
name: Hauck, Nura
name: Rödiger, Cora Maria
name: Heraeus, Stefanie
name: Holzschuh, Olga
name: Meyer, Isabel
name: Reglin, Rahel
Publisher: name: Universität Kassel
Year: 2015
Subjects: subject: 720
subject: 900
subject: Kassel
subject: Museum
subject: Geschichte 1700-2011

description: Dies ist eine Sicherung der nicht mehr existierende Website "https://www.museumsgeschichte.uni-kassel.de/" im PDF- und im WARC-Format (11/2023).

Eine archivierte Version ist außerdem unter https://web.archive.org/web/20231113210853/https://www.museumsgeschichte.uni-kassel.de/ zu finden.
Additional file 3: of Residual feed intake phenotype and gender affect the expression of key genes of the lipogenesis pathway in subcutaneous adipose tissue of beef cattle
Creators: name: McKenna, Clare
name: Porter, Richard
name: Keogh, Kate
name: Sinead Waters
name: McGee, Mark
name: Kenny, David
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Correlogram highlighting the correlation between all adipose tissue candidate genes from adipose tissue, Backfat measurements and RFI. Visual representation of the correlation matrix between RFI, Backfat change and all genes measured Blue circles (correlation value 1) indicate a positive correlation while red (correlation value â â 1) indicate a negative correlation. (DOCX 296 kb)
Topological invariants for the Haldane phase of interacting SSH chains -- a functional RG approach
Creators: name: Sbierski, Björn
name: Karrasch, Christoph
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a functional renormalization group approach to interacting topological Green function invariants with a focus on the nature of transitions. The method is applied to chiral symmetric fermion chains in the Mott limit that can be driven into a Haldane phase. We explicitly show that the transition to this phase is accompanied by a zero of the fermion Green function. Our results for the phase boundary are quantitatively benchmarked against DMRG data.
Smart Cities and Digital Twins as Drivers for the Digital Transformation in the Public Sector of Japan: Report
Creators: name: Haller, Stephan
Publisher: name: Berner Fachhochschule, Wirtschaft, Institut Public Sector Transformation (IPST)
Year: 2024
Subjects: Smart City
Digital Twin
Data Space
Digital Transformation
Japan
Society 5.0

description: This report gives an overview of the digital transformation in Japan based on the Society 5.0 vision and the Digital Garden City Nation concept. The focus is on smart cities and urban digital twins, as they can be considered to be two of the main drivers for digital transformation in Japan.
Anisotropic Error Estimates of The Linear Nonconforming Virtual Element Methods
Creators: name: Cao, Shuhao
name: Chen, Long
Publisher: name: arXiv
Year: 2018
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65N12, 65N15, 65N30, 46E35

description: A refined a priori error analysis of the lowest order (linear) nonconforming Virtual Element Method (VEM) for approximating a model Poisson problem is developed in both 2D and 3D. A set of new geometric assumptions is proposed on shape regularity of polytopal meshes. A new error equation for the lowest order (linear) nonconforming VEM is derived for any choice of stabilization, and a new stabilization using a projection on an extended element patch is introduced for the error analysis on anisotropic elements.
Detectability of gravitational wave bursts from a class of neutron star starquake GRB models
Creators: name: Horvath, J. E.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A large class of gamma-ray burst (GRB) models (overwhelming until recently) involve the release of energy in a neutron star quake. Even though the extreme isotropy of the GRB sky established by the BATSE experiment has now shifted the interest to cosmological models, the former starquake scenarios are still attractive and may naturally produce a gravitational wave burst that carries most of the released energy. We discuss the prospects for detection of these high-frequency bursts by the forthcoming interferometers and spheroidal antennas, emphasizing the most recent results on the distribution and nature of GRB sources. We find that, even if the overall picture is correct, the positive detection of GRB-associated gravitational wave bursts is unlikely and therefore these events will not be a prime target for the detectors.
description: 12 pp., PlainTex file, no figures. To appear in Int.Jour.Mod.Phys.D
Redefining electrosensitivity: A new literature-supported model
Creators: name: Redmayne, Mary
name: Reddel, Siobhan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: In critically examining literature on electrohypersensitivity and the reported somatic responses to anthropogenic modulated radiofrequency radiation (RFR) exposure, it becomes apparent that electrohypersensitivity is one part of a range of consequences. Current evidence on the necessity of considering patients’ overall health status leads us to propose a new model in which electrohypersensitivity is but part of the electrosensitive status inherent in being human. We propose the likelihood and type of response to environmental RFR include i) a linear somatic awareness continuum, ii) a non-linear somatic response continuum, and iii) the extent of each individual’s capacity to repair damage (linked to homeostatic response). We anticipate this last, dynamic, aspect is inextricably linked to the others through the autonomic nervous system. The whole is dependent upon the status of the interconnected immune and inflammatory systems. This holistic approach leads us to propose various outcomes. For most, their body maintains homeostasis by routine repair. However, some develop electrohypersensitivity either due to RFR exposure or as an ANS-mediated, unconscious response (aka nocebo effect), or both. We suggest RFR exposure may be one factor in the others developing an auto-immune disease or allergy. A few develop delayed catastrophic disease such as glioma. This model gives the blanket term ElectroMagnetic Illness (EMI) to all RFR-related conditions. Thus, EHS appears to be one part of a range of responses to a novel and rapidly changing evolutionary situation.
Additional file 1: of Capturing foraging and resting behavior using nested multivariate Markov models in an air-breathing marine vertebrate
Creators: name: Weinstein, Ben
name: Ladd Irvine
name: Friedlaender, Ari
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Table S1. Parameter estimates for the humpback foraging, traveling, and resting behavioral states inferred from the nested multivariate movement model. (DOCX 19 kb)
Additional file 5 of Increased Wnt/β-catenin signaling contributes to autophagy inhibition resulting from a dietary magnesium deficiency in injury-induced osteoarthritis
Creators: name: Bai, Ruijun
name: Miao, Michael Z.
name: Li, Hui
name: Wang, Yiqing
name: Hou, Ruixue
name: He, Ke
name: Wu, Xuan
name: Jin, Hongyu
name: Zeng, Chao
name: Cui, Yang
name: Lei, Guanghua
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Science Policy
subject: Developmental Biology

description: Additional file 5: Supplemental Figure 5. Catenin, Wnt3a, Wnt5a, Wnt5b and Wnt16 genes expression. Mouse chondrocytes were cultured under different magnesium conditions (0.7mM, 0,4mM and 0.1mM). mRNA levels of Catenin, Wnt3a, Wnt5a, Wnt5b and Wnt16 were investigated by qRT-PCR (n = 5). Hprt1 was used as housekeeping gene. Data were expressed as the mean ± SD and analyzed by one-way ANOVA test. (*P<0.05, **P<0.01, ***P<0.001, ****P<0.0001).
Beharrlich, strategisch, integriert. Zur Vorhersage akademischer Studienadaptation von Lehramtsstudierenden durch Beharrlichkeit und den Einsatz von Lernstrategien
Creators: name: Malai, Dumitru
name: Vogel, Sebastian
name: Lipowsky, Frank
Publisher: name: Universität Kassel
Year: 2023
Subjects: subject: Akademische Studienadaption
subject: Lernstrategien
subject: Beharrlichkeit
subject: academic college adjustment
subject: learning strategies
subject: tenacity
subject: 370
subject: Lehramtsstudium
subject: Anpassung
subject: Lerntechnik
subject: Beharrlichkeit
subject: Lernmotivation

description: Gefördert im Rahmen des Projekts DEAL
Tunable charge qubit based on barrier-controlled triple quantum dots
Creators: name: Yang, Xu-Chen
name: Chan, Guo Xuan
name: Wang, Xin
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a theoretical proposal of a tunable charge qubit, hosted in triple quantum dots. The manipulation is solely performed by changing the heights of the two potential barriers between the three dots, while the energy of all three dots are fixed. We have found that when the relative height of the two barriers are changed, the direction of the axis of rotation in performing single-qubit gates can be varied. On the other hand, the corresponding rotation speed can be tuned by raising or lowering the two barriers at the same time. Our proposal therefore allows for tunability of both the rotation axis and rotating speed for a charge qubit via all-electrical control, which may facilitate realization of quantum algorithms in these devices.
description: 8+ pages, 9 figures
The Data We Own: A How-To Guide for Environmental Data Sharing
Creators: name: Richards, Cathy
Publisher: name: Zenodo
Year: 2025
Subjects: data sharing
environmental data
data governance
data stewardship
environmental justice

description: The Data We Own: A How-To Guide for Environmental Data Sharing is a digital zine designed to help environmental and climate justice organizations navigate the complexities of sharing data responsibly and equitably. Data sharing is a fundamental part of innovation for environmental justice because it enables collaboration, amplifies community voices, and supports evidence-based decision making to address systemic inequities. This guide prompts considerations and conversations around practices like data protection, transparency, and equitable access to ensure justice remains a key piece of environmental efforts.
Mus amphibius Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Muridae
Mus
Mus amphibius

description: Mus amphibius [spec. nov.]
M. cauda elongata pilosa, plantis palmatis. �
Mus major aquaticus s. Rattus aquaticus. Raj. quadr. 217.
Mus aquaticus. Bell. aquat. 35. t. 36.
Habitat in Europae, Africae fossis, ripis, piscinis, hortis.
Species mihi non rite cognita.
Fodit ad fossas & radices arborum, natat, urinatur, consumit radices, Hortis & satis infestus, capitur Nassis e virgulis confectis sub aqua demersis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 61, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206