cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Black holes and Large $N$ complex saddles in 3D-3D correspondence
Creators: name: Choi, Sunjin
name: Gang, Dongmin
name: Kim, Nakwoo
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Geometric Topology (math.GT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We study the large $ N$ sign oscillation of the twisted indices for 3D theories of class $\mathcal{R}$ obtained from M5-branes wrapped on a hyperbolic 3-manifold. Holographically, the oscillatory behavior can be understood from the imaginary part of on-shell actions for the two Euclidean supergravity solutions, Bolt$_{\pm}$ with $p=0$, which are Wick rotation of magnetically charged AdS$_4$ black holes. The two solutions have the same imaginary part with opposite sign. The imaginary part comes from the $F\wedge F$-term in the supergravity and the coefficient is proportional to the Chern-Simons invariant of 3-manifold. Combining the holographic computation with 3D-3D relation for twisted indices, we propose a non-trivial mathematical conjecture regarding the phase factor of a twisted Reidemeister-Ray-Singer torsion on hyperbolic 3-manifold.
description: 13 pages
Cinetochilum margaritaceum Perty 1852
Creators: name: Durán-Ramírez, Carlos Alberto
name: Dias, Roberto Júnio Pedroso
name: Estrada, Rosaura Mayén-
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Chromista
Ciliophora
Oligohymenophorea
Hymenostomatida
Cinetochilidae
Cinetochilum
Cinetochilum margaritaceum

description: Cinetochilum margaritaceum (Ehrenberg, 1830) Perty, 1852
Distribution. BRAZIL: Paraná River between the Nupelia’s Field Station and the district of Porto São José, São Pedro do Paraná (Buosi et al. 2014 b, 2015), (Ad). DOMINICAN REPUBLIC: (Foissner et al. 2003).
description: Published as part of Durán-Ramírez, Carlos Alberto, Dias, Roberto Júnio Pedroso & Estrada, Rosaura Mayén-, 2020, Checklist of ciliates (Alveolata: Ciliophora) that inhabit in bromeliads from the Neotropical Region, pp. 1-36 in Zootaxa 4895 (1) on page 32, DOI: 10.11646/zootaxa.4895.1.1, http://zenodo.org/record/4321437
Anwendung blutbasierter Biomarker bei Herzinsuffizienz mit erhaltener systolischer LV-Funktion
Creators: name: Trippel, Tobias Daniel
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: heart failure
subject: biomarkers
subject: heart failure with preserved ejection fraction
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Die vorliegende Arbeit beschäftigt sich mit der Anwendung blutbasierter Biomarker bei Herzinsuffizienz (HI) mit erhaltener systolischer LV-Funktion (HFpEF). Die historische Entwicklung von der Beschreibung der Biomarker bei der HI hin zur Verankerung ihrer Nutzung in den internationalen medizinischen Leitlinien und zunehmend der biomarkerbasierten Festigung der klinischen Diagnose HI und HFpEF wird dargestellt. Mit dem Verständnis von HFpEF als systemisches Syndrom, rücken neben den verschiedenen Verwendungsmöglichkeiten der Biomarker als Werkzeuge des Screenings, der Diagnose, der Risikostratifizierung und als therapeutisches Surrogat auch unterschiedliche Krankheitsdimensionen oder durch Biomarker repräsentierte pathophysiologische Achsen zunehmend in den Mittelpunkt der Betrachtung. Dies wird durch vorgelegte Originalarbeit am Beispiel des diagnostischen und prognostischen Mehrwertes von Galectin-3, dem auf Basis von Metabolomics und Lipidomis identifizierten und validierten Cardiac Lipid Panel Multi-Biomarker-Scores, dem Nachweis von Auto-Antikörpern gegen den Beta-1-Adrenergen-Rezeptor mittels eines neuen ELISA, einer vergleichenden Biomarker Studie zu natriuretischen Peptiden und Copeptin in der akuten Herzinsuffizienz sowie einer biomarker-basierten Therapiestudie mit den Endpunkt des kardialen Fibrosesurrogates exemplarisch dargestellt und diskutiert. Die klinischen Konsequenzen sind in der adäquaten Auswahl der anzuwendenden Biomarker und der Betrachtung verschiedener Krankheitsdimensionen und Stadien des Syndroms HFpEF zu sehen. Multi-Biomarker Strategien und serielle Bestimmungen sind mit der Verfügbarkeit von high sensitivity multiplex assays im Kontext der HI künftig zu erwarten.
Workshop day 1: Microphone check
Creators: name: Parker, Verdena
name: Ammon, Danny
name: Begay, Kayla
name: Escamilla, Ramón
name: George-Moore, Melodie
name: Newbold, Lindsey
name: Lincoln, Perry
name: Parker, Otis
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2022
Subjects: subject: hup

description: Audio files VP-250311-03 and VP-250311-04: Microphone check, stating the date (given incorrectly in VP-250311-03, corrected in VP-250311-04), with discussion of some of the activities planned for the week. Recorded in a school classroom in Hoopa Valley as part of a language workshop. The participants identified here were present at most sessions during the workshop; additional people were also present, some of whom participate in the conversation.
Tonkinospira suturata Pall-Gergely & Grego 2019, new species
Creators: name: Páll-Gergely, Barna
name: Grego, Jozef
name: Vermeulen, Jaap J.
name: Reischütz, Alexander
name: Hunyadi, András
name: Jochum, Adrienne
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Gastrocoptidae
Tonkinospira
Tonkinospira suturata

description: Tonkinospira suturata Páll-Gergely & Grego, new species (Fig. 11) Type material. Holotype (H: 1.41 mm, D: 1.84 mm, Fig. 11) (HNHM 104405), Laos, Khammouane Province, Tham Nam Dôn Cave, Earthquake Dome, sand sediments at bank of cave river, 160 m a.s.l., 17°33.815′N, 104°52.298′E (locality code: JG2 B), coll. J. Grego., 11 February 2017; 2 damaged paratypes (coll. JG), same data as preceding. Diagnosis. A large Tonkinospira species with a depressed conical shell, rounded body whorl, fine radial growth lines and without spiral striation, a wide umbilicus, and a peristome that is not adnate to penultimate whorl. Description. Shell large for the genus; depressed conical with rounded body whorl; shell wider than tall; 4.25 whorls, regularly increasing, separated by a very deep suture; whorls shouldered; protoconch consists of 1.5 whorls, with extremely fine radial growth lines and without spiral striation (on the first whorl of protoconch some spiral striae visible, but they are not regular, probably due to erosion of the shell surface); teleoconch overall weakly sculptured, with irregular, fine radial growth lines, and relatively dense, regular, obscure spiral striation, ca. 22 in number in the middle shell line from apertural view; aperture almost in alignment with penultimate whorl and very slightly oblique to shell axis in lateral view; aperture rounded-ovate, slightly free from the preceding whorl along the parietal margin; peristome very slightly expanded, not reflected; aperture not adnate to penultimate whorl, protruding into a truncated tuba (best seen from umbilical perspective); two weak, very low suggestions of parietal barriers are discernible; umbilicus wider than narrow. Differential diagnosis. The most similar species in terms of shell size and the weak sculpture is T. tomasini, which has a much more elevated spire, and adnate peristome and a more oblique aperture to the shell axis. Etymology. The specific epithet suturata refers to the deep suture of the new species.
description: Published as part of Páll-Gergely, Barna, Grego, Jozef, Vermeulen, Jaap J., Reischütz, Alexander, Hunyadi, András & Jochum, Adrienne, 2019, New Tonkinospira Jochum, Slapnik & Páll-Gergely, 2014 species from Laos and Vietnam (Gastropoda: Pulmonata: Hypselostomatidae), pp. 517-535 in Raffles Bulletin of Zoology 67 on pages 529-533, DOI: 10.26107/RBZ-2019-0041, http://zenodo.org/record/4576444
TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch
Creators: name: Wilzopolski, Jenny
name: Kietzmann, Manfred
name: Mishra, Santosh K.
name: Stark, Holger
name: Bäumer, Wolfgang
name: Rossbach, Kristine
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: histamine
subject: histamine H1 receptor
subject: histamine H4 receptor
subject: itch
subject: signal transduction
subject: TRPV1
subject: TRPA1
subject: dorsal root ganglion neurons (DRG)
subject: Ca2+-imaging
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik

description: Two histamine receptor subtypes (HR), namely H1R and H4R, are involved in the transmission of histamine-induced itch as key components. Although exact downstream signaling mechanisms are still elusive, transient receptor potential (TRP) ion channels play important roles in the sensation of histaminergic and non-histaminergic itch. The aim of this study was to investigate the involvement of TRPV1 and TRPA1 channels in the transmission of histaminergic itch. The potential of TRPV1 and TRPA1 inhibitors to modulate H1R- and H4R-induced signal transmission was tested in a scratching assay in mice in vivo as well as via Ca2+ imaging of murine sensory dorsal root ganglia (DRG) neurons in vitro. TRPV1 inhibition led to a reduction of H1R- and H4R- induced itch, whereas TRPA1 inhibition reduced H4R- but not H1R-induced itch. TRPV1 and TRPA1 inhibition resulted in a reduced Ca2+ influx into sensory neurons in vitro. In conclusion, these results indicate that both channels, TRPV1 and TRPA1, are involved in the transmission of histamine-induced pruritus.
Physiological Shear Stress Enhances Differentiation, Mucus-Formation and Structural 3D Organization of Intestinal Epithelial Cells In Vitro
Creators: name: Lindner, Marcus
name: Laporte, Anna
name: Block, Stephan
name: Elomaa, Laura
name: Weinhart, Marie
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: 3D-printed insert chamber
subject: bioreactor
subject: cell-based mucus model
subject: cellular self-organization
subject: CFD simulation
subject: goblet cell differentiation
subject: native mucus thickness
subject: physiological fluid flow
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Gastrointestinal (GI) mucus plays a pivotal role in the tissue homoeostasis and functionality of the gut. However, due to the shortage of affordable, realistic in vitro GI models with a physiologically relevant mucus layer, studies with deeper insights into structural and compositional changes upon chemical or physical manipulation of the system are rare. To obtain an improved mucus-containing cell model, we developed easy-to-use, reusable culture chambers that facilitated the application of GI shear stresses (0.002–0.08 dyn∙cm−2) to cells on solid surfaces or membranes of cell culture inserts in bioreactor systems, thus making them readily accessible for subsequent analyses, e.g., by confocal microscopy or transepithelial electrical resistance (TEER) measurement. The human mucus-producing epithelial HT29-MTX cell-line exhibited superior reorganization into 3-dimensional villi-like structures with highly proliferative tips under dynamic culture conditions when compared to static culture (up to 180 vs. 80 µm in height). Additionally, the median mucus layer thickness was significantly increased under flow (50 ± 24 vs. 29 ± 14 µm (static)), with a simultaneous accelerated maturation of the cells into a goblet-like phenotype. We demonstrated the strong impact of culture conditions on the differentiation and reorganization of HT29-MTX cells. The results comprise valuable advances towards the improvement of existing GI and mucus models or the development of novel systems using our newly designed culture chambers.
Large Farm Animals Used for Research Purposes: A Survey on Purchase, Housing and Hygiene Management
Creators: name: Schmidt, Tanja
name: Ferrara, Fabienne
name: Pobloth, Anne-Marie
name: Jeuthe, Sarah
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: farm animals
subject: survey
subject: preclinical research
subject: agricultural research
subject: hygiene monitoring
subject: health
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: Background: Farm animals (FAs) are frequently used in biomedical research. Recommendations for the purchase, housing and health monitoring of these animals (sheep, goats, cattle and pigs) are still missing, and many institutes have developed their own strategies and protocols to face the challenges associated with the use of farm animals. This may influence the comparability of research results and increase data variances, thus increasing animal use that contradicts the obligation to apply the 3Rs principle of reduction, refinement and replacement required in Directive 2010/63 EU and the German animal protection law. Methods: A survey was conducted to define the current state of the art in research institutes working with pigs, and large and small ruminants. Results: The results of the survey clearly show that there are no uniform procedures regarding the purchase, housing and hygiene management of farm animals contrary to small laboratory animals. The facilities make purpose-bound decisions according to their own needs and individual work instructions and implement their own useful protocols to improve and maintain the health of the animals. Conclusion: This survey was the first step to filling the gaps and identifying the status quo and practical applied measures regarding the purchase and hygiene monitoring of FAs in order to improve animal welfare and scientific validity.
Sphingolipids: Effectors and Achilles Heals in Viral Infections?
Creators: name: Schneider-Schaulies, Sibylle
name: Schumacher, Fabian
name: Wigger, Dominik
name: Schöl, Marie
name: Waghmare, Trushnal
name: Schlegel, Jan
name: Seibel, Jürgen
name: Kleuser, Burkhard
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: glycosphingolipids
subject: ceramides
subject: sphingosine 1-phosphate
subject: sphingomyelinase
subject: HIV
subject: SARS-CoV-2
subject: measles
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik

description: As viruses are obligatory intracellular parasites, any step during their life cycle strictly depends on successful interaction with their particular host cells. In particular, their interaction with cellular membranes is of crucial importance for most steps in the viral replication cycle. Such interactions are initiated by uptake of viral particles and subsequent trafficking to intracellular compartments to access their replication compartments which provide a spatially confined environment concentrating viral and cellular components, and subsequently, employ cellular membranes for assembly and exit of viral progeny. The ability of viruses to actively modulate lipid composition such as sphingolipids (SLs) is essential for successful completion of the viral life cycle. In addition to their structural and biophysical properties of cellular membranes, some sphingolipid (SL) species are bioactive and as such, take part in cellular signaling processes involved in regulating viral replication. It is especially due to the progress made in tools to study accumulation and dynamics of SLs, which visualize their compartmentalization and identify interaction partners at a cellular level, as well as the availability of genetic knockout systems, that the role of particular SL species in the viral replication process can be analyzed and, most importantly, be explored as targets for therapeutic intervention.
Constructing Functional Braids for Low-Leakage Topological Quantum Computing
Creators: name: Xu, Haitan
name: Wan, Xin
Publisher: name: arXiv
Year: 2008
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We discuss how to significantly reduce leakage errors in topological quantum computation by introducing an irrelevant error in phase, using the construction of a CNOT gate in the Fibonacci anyon model as a concrete example. To be specific, we construct a functional braid in a six-anyon Hilbert space that exchanges two neighboring anyons while conserving the encoded quantum information. The leakage error is $\sim$$10^{-10}$ for a braid of $\sim$100 interchanges of anyons. Applying the braid greatly reduces the leakage error in the construction of generic controlled-rotation gates.
description: 5 pages, 4 figures, updated, accepeted by Phys. Rev. A
Multi-excitonic complexes in single InGaN quantum dots
Creators: name: Seguin, R.
name: Rodt, S.
name: Strittmatter, A.
name: Reißmann, L.
name: Bartel, T.
name: Hoffmann, A.
name: Bimberg, D.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Cathodoluminescence spectra employing a shadow mask technique of InGaN layers grown by metal organic chemical vapor deposition on Si(111) substrates are reported. Sharp lines originating from InGaN quantum dots are observed. Temperature dependent measurements reveal thermally induced carrier redistribution between the quantum dots. Spectral diffusion is observed and was used as a tool to correlate up to three lines that originate from the same quantum dot. Variation of excitation density leads to identification of exciton and biexciton. Binding and anti-binding complexes are discovered.
description: 3 pages, 4 figures
Dalitz plot analysis of the D^+ -> K^-pi^+pi^+ decay
Creators: name: CLEO Collaboration
name: Bonvicini, G.
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We perform a Dalitz plot analysis of D^+ -> K^-pi^+pi^+ decay with the CLEO-c data set of 572 pb^-1 of e^+e^- collisions accumulated at the psi(3770). This corresponds to 1.6 million D^+D^- pairs from which we select 140793 candidate events with a small background of 1.1%. We compare our results with previous measurements using the isobar model. We modify the isobar model with improved description of some of the contributing resonances, and get better agreement with our data. We also consider a quasi-model-independent approach and measure the magnitude and phase of the contributing K pi S wave in the range of invariant masses from the threshold to the maximum in this decay. This gives an improved descriptions of our data over the isobar model. Finally we allow for an isospin-two pi^+pi^+ S-wave contribution, and find that adding this to both the isobar model and quasi-model-independent approach gives the best description of our data.
description: 33 pages, available through http://www.lns.cornell.edu/public/CLNS/, published in Phys. Rev. D 78, 052001 (2008)
Holophryxus giardi Richardson 1908
Creators: name: Huys, Rony
name: Savchenko, Alexandra S.
name: Kosobokova, Ksenia N.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Isopoda
Dajidae
Holophryxus
Holophryxus giardi

description: HOLOPHRYXUS GIARDI RICHARDSON, 1908
Original description: Richardson (1908): 690–693, figs 1–3 (adult and immature ♀♀).
Host: Boreogennema borealis (Dendrobranchiata, Benthesicymidae).
Distribution: North Pacific Ocean (Table 2).
Differential diagnosis: Holophryxus. Body length 8 mm (immature ♀), 39 mm (adult ♀; N = 1) (Richardson, 1908). Colour uniformly light yellow in ♀; unconfirmed in ♂.
FEMALE: Body spindle shaped, about 2.2 times as long as maximum width. Cephalon demarcated from pereon by lateral constrictions in dorsal aspect and by shallow dorsal fold in lateral aspect; dorsal prominence with emarginate (bilobed) anterior margin; with broad hood-like extension with virtually straight anterior margin and rounded frontolateral corners; ventral cephalic ridge not discernible in dorsal aspect, relatively small and slightly arched, about 0.3 times as long as wide, anterior margin slightly rounded, presence of pit organs unconfirmed; posterolateral corners of cephalic ridge produced into weakly developed pointed processes, representing coxal plates of incorporated first pereonite. Maxilliped and sternal plate not observed. Pereon with five pairs of incubatory plates; shape of oostegite 1 unconfirmed; oostegite 5 unilobate, covering about 60% of ventral side of body, posterior margin with minute spiniform extensions but number unconfirmed. Coxal plates of pereopods 2–5 expressed, represented by spinous processes on lateroventral margins of pereon, separated by transverse folds. Presence/absence of ventrolateral papillae on posterior part of pereon unconfirmed. Pleon demarcated from pereon by lateral and (particularly) ventral constrictions; about 15% of total body length; lobate with posterior margin broadly rounded.
description: Published as part of Huys, Rony, Savchenko, Alexandra S. & Kosobokova, Ksenia N., 2023, Discovery of a new species and host record of Holophryxus Richardson, 1905 (Isopoda: Dajidae) from the central Arctic: a model of enhanced descriptive standards for epicaridean isopods, pp. 592-649 in Zoological Journal of the Linnean Society 198 (2) on page 632, DOI: 10.1093/zoolinnean/zlac105, http://zenodo.org/record/8011009
Conjugation Dynamics of Self-Transmissible and Mobilisable Plasmids into E. coli O157:H7 on Arabidopsis thaliana Rosettes
Creators: name: Remus-Emsermann, Mitja N. P.
name: Aicher, David
name: Pelludat, Cosima
name: Gisler, Pascal
name: Drissner, David
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: antibiotic resistance
subject: conjugation
subject: plasmids
subject: phyllosphere
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::579 Mikroorganismen, Pilze, Algen

description: Many antibiotic resistance genes present in human pathogenic bacteria are believed to originate from environmental bacteria. Conjugation of antibiotic resistance conferring plasmids is considered to be one of the major reasons for the increasing prevalence of antibiotic resistances. A hotspot for plasmid-based horizontal gene transfer is the phyllosphere, i.e., the surfaces of aboveground plant parts. Bacteria in the phyllosphere might serve as intermediate hosts with transfer capability to human pathogenic bacteria. In this study, the exchange of mobilisable and self-transmissible plasmids via conjugation was evaluated. The conjugation from the laboratory strain Escherichia coli S17-1, the model phyllosphere coloniser Pantoea eucalypti 299R, and the model pathogen E. coli O157:H7 to the recipient strain E. coli O157:H7::MRE103 (EcO157:H7red) in the phyllosphere of Arabidopsis thaliana was determined. The results suggest that short-term occurrence of a competent donor is sufficient to fix plasmids in a recipient population of E. coli O157:H7red. The spread of self-transmissible plasmids was limited after initial steep increases of transconjugants that contributed up to 10% of the total recipient population. The here-presented data of plasmid transfer will be important for future modelling approaches to estimate environmental spread of antibiotic resistance in agricultural production environments.
The Effect of Kinesthetic Learning Strategies on the Engagement of Middle School Students
Creators: name: Gonzales, Jonathon
Publisher: name: Maryland Shared Open Access Repository
Year: 2014
Subjects: subject: Education -- Research papers (Graduate)

description: The purpose of this study was to determine if the implementation of kinesthetic learning
strategies influenced the engagement of students in an eighth grade English Language
Arts class. This study used a quasi-experimental pre/post-test design to determine how
kinesthetic learning strategies affect student engagement. The “Middle School Survey of
Student Engagement,” developed by the researcher, was used in this study. This
instrument was based on the “National Survey of Student Engagement.” Although three
areas of student engagement showed significant differences, the other five areas of
student engagement displayed no differences. The threats to validity in this study
demonstrate that improvements could be made in order to better determine the actual
effect of kinesthetic learning strategies on student engagement. Creating more studentcentered
and differentiated learning opportunities is intended to provide students with
more accessibility and ownership in their learning experiences; therefore, future studies
and instructional practices should include the implementation of kinesthetic learning
strategies for the purpose of analyzing and exploring their effects on student engagement.
Frequency-Temperature Crossover in the Conductivity of Disordered Luttinger Liquids
Creators: name: Rosenow, Bernd
name: Glatz, Andreas
name: Nattermann, Thomas
Publisher: name: arXiv
Year: 2006
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The temperature ($T$) and frequency ($ω$) dependent conductivity of weakly disordered Luttinger liquids is calculated in a systematic way both by perturbation theory and from a finite temperature renormalization group (RG) treatment to leading order in the disorder strength. Whereas perturbation theory results in $ω/T$ scaling of the conductivity such scaling is violated in the RG traetment. We also determine the non-linear field dependence of the conductivity, whose power law scaling is different from that of temperature and frequency dependence.
description: 4 pages, 4 figures
Effects of Daily Mathematical Problem Solving Instruction on High School Special Education Students
Creators: name: Damvakaris, Emma Fulton
Publisher: name: Maryland Shared Open Access Repository
Year: 2014
Subjects: subject: Math problem solving
subject: Word problems
subject: Special education
subject: High school
subject: Math disability
subject: Problem solving strategies
subject: Math understanding
subject: Math comprehension
subject: Writing in math
subject: Education -- Research papers (Graduate)

description: The purpose of this study was to determine the impact of two variations of daily
mathematical word problem instruction on high school special education students in selfcontained
algebra classes. One group of students received instruction on word problems
that was designed around student interests, while the other group received instruction
using generic word problems from the curriculum. The measurement tools were parallel
12 item pre- and posttests comprised of items reflecting six major types of algebraic word
problems. The pretest, given prior to treatment, was followed by six weeks of instruction
on mathematical problem solving using the 5-Step Problem Solving Plan. The posttest
was given at the end of treatment. The results of the study indicated that both groups of
students showed gains in mathematical understanding and written expression. However,
there was no significant difference in mean achievement gains of the students who were
instructed using real life personalized problems and those who were instructed using
generic problems. Research should continue to assess ways to develop effective
strategies for improving the mathematical problem-solving skills of special education
students.
Interaction of Linear Polyelectrolytes with Proteins: Role of Specific Charge-Charge Interaction and Ionic Strength
Creators: name: Bukala, Julia
name: Yavvari, Prabhusrinivas
name: Walkowiak, Jacek J.
name: Ballauff, Matthias
name: Weinhart, Marie
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: polycation
subject: ITC
subject: complex formation
subject: counterion release
subject: thermodynamic analysis
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: We present a thermodynamic study of the interaction of synthetic, linear polyelectrolytes with bovine serum albumin (BSA). All polyelectrolytes are based on poly(allyl glycidyl ether) which has been modified by polymer-analogous reaction with anionic (-SO3Na), cationic (-NH3Cl or -NHMe2Cl) or zwitterionic groups (-NMe2(CH2)3SO3). While the anionic polymer shows a very weak interaction, the zwitterionic polymer exhibits no interaction with BSA (pI = 4.7) under the applied pH = 7.4, ionic strength (I = 23–80 mM) and temperature conditions (T = 20–37 °C). A strong binding, however, was observed for the polycations bearing primary amino or tertiary dimethyl amino groups, which could be analysed in detail by isothermal titration calorimetry (ITC). The analysis was done using an expression which describes the free energy of binding, ΔGb, as the function of the two decisive variables, temperature, T, and salt concentration, cs. The underlying model splits ΔGb into a term related to counterion release and a term related to water release. While the number of released counter ions is similar for both systems, the release of bound water is more important for the primary amine compared to the tertiary N,N-dimethyl amine presenting polymer. This finding is further traced back to a closer contact of the polymers’ protonated primary amino groups in the complex with oppositely charged moieties of BSA as compared to the bulkier protonated tertiary amine groups. We thus present an investigation that quantifies both driving forces for electrostatic binding, namely counterion release and change of hydration, which contribute to a deeper understanding with direct impact on future advancements in the biomedical field.
Simplified Design of Optical Elements for Filled-Aperture Coherent Beam Combination
Creators: name: Aleshire, Christopher
name: Steinkopff, Albrecht
name: Jauregui, Cesar
name: Klenke, Arno
name: Tünnermann, Andreas
name: Limpert, Jens
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: A simplification strategy for Segmented Mirror Splitters (SMS) used as beam combiners is presented. These devices are useful for compact beam division and combination of linear and 2-D arrays. However, the standard design requires unique thin-film coating sections for each input beam and thus potential for scaling to high beam-counts is limited due to manufacturing complexity. Taking advantage of the relative insensitivity of the beam combination process to amplitude variations, numerical techniques are used to optimize highly-simplified designs with only one, two or three unique coatings. It is demonstrated that with correctly chosen coating reflectivities, the simplified optics are capable of high combination efficiency for several tens of beams. The performance of these optics as beamsplitters in multicore fiber amplifier systems is analyzed, and inhomogeneous power distribution of the simplified designs is noted as a potential source of combining loss in such systems. These simplified designs may facilitate further scaling of filled-aperture coherently combined systems.
description: 11 pages, 7 figures
Workshop day 1: Discussion of local area and a story about a woman warrior
Creators: name: Parker, Verdena
name: Ammon, Danny
name: Begay, Kayla
name: Escamilla, Ramón
name: George-Moore, Melodie
name: Newbold, Lindsey
name: Lincoln, Perry
name: Parker, Otis
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2022
Subjects: subject: hup

description: Audio files VP-250311-01 and VP-250311-02: Discussion of various topics related to places in Hoopa Valley and local history. This includes an account of strange happenings at a site that was once the women's training place; a story about a woman warrior, told in Hupa and then in English; the involvement of women in battles; Verdena's training when she was young; a prayer for strength, in Hupa; discussion of territories near Hoopa Valley. Recorded in a school classroom in Hoopa Valley as part of a language workshop. The participants identified here were present at most sessions during the workshop; additional people were also present, some of whom participate in the conversation.
Equilibrium (Zipf) and Dynamic (Grasseberg-Procaccia) method based analyses of human texts. A comparison of natural (english) and artificial (esperanto) languages
Creators: name: Ausloos, M.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Computation and Language (cs.CL)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: A comparison of two english texts from Lewis Carroll, one (Alice in wonderland), also translated into esperanto, the other (Through a looking glass) are discussed in order to observe whether natural and artificial languages significantly differ from each other. One dimensional time series like signals are constructed using only word frequencies (FTS) or word lengths (LTS). The data is studied through (i) a Zipf method for sorting out correlations in the FTS and (ii) a Grassberger-Procaccia (GP) technique based method for finding correlations in LTS. Features are compared : different power laws are observed with characteristic exponents for the ranking properties, and the {\it phase space attractor dimensionality}. The Zipf exponent can take values much less than unity ($ca.$ 0.50 or 0.30) depending on how a sentence is defined. This non-universality is conjectured to be a measure of the author $style$. Moreover the attractor dimension $r$ is a simple function of the so called phase space dimension $n$, i.e., $r = n^λ$, with $λ= 0.79$. Such an exponent should also conjecture to be a measure of the author $creativity$. However, even though there are quantitative differences between the original english text and its esperanto translation, the qualitative differences are very minutes, indicating in this case a translation relatively well respecting, along our analysis lines, the content of the author writing.
description: 22 pages, 87 references, 5 tables, 8 figures
Baumert, Norbert: Koinonein und Metechein - synonym?
Creators: name: Niebuhr, Karl-Wilhelm
Publisher: name: Ökumenische Rundschau
Year: 2025

description: Ökumenische Rundschau, Bd. 56 Nr. 3 (2007): Ökumenische Rundschau, Band 56, Heft 3
Tumor Necrosis Factor Alpha Effects on the Porcine Intestinal Epithelial Barrier Include Enhanced Expression of TNF Receptor 1
Creators: name: Droessler, Linda
name: Cornelius, Valeria
name: Markov, Alexander G.
name: Amasheh, Salah
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: claudins
subject: epithelial barrier
subject: IPEC-J2
subject: ML-7
subject: tight junction
subject: TNFα
subject: TNFR-1
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Tumor necrosis factor alpha (TNFα) has been shown to impair the intestinal barrier, inducing and maintaining inflammatory states of the intestine. The aim of the current study was to analyze functional, molecular and regulatory effects of TNFα in a newly established non-transformed jejunal enterocyte model, namely IPEC-J2 monolayers. Incubation with 1000 U/mL TNFα induced a marked decrease in transepithelial electrical resistance (TEER), and an increase in permeability for the paracellular flux marker [3H]-D-mannitol compared to controls. Immunoblots revealed a significant decrease in tight junction (TJ) proteins occludin, claudin-1 and claudin-3. Moreover, a dose-dependent increase in the TNF receptor (TNFR)-1 was detected, explaining the exponential nature of pro-inflammatory effects, while TNFR-2 remained unchanged. Recovery experiments revealed reversible effects after the removal of the cytokine, excluding apoptosis as a reason for the observed changes. Furthermore, TNFα signaling could be inhibited by the specific myosin light chain kinase (MLCK) blocker ML-7. Results of confocal laser scanning immunofluorescence microscopy were in accordance with all quantitative changes. This study explains the self-enhancing effects of TNFα mediated by MLCK, leading to a differential regulation of TJ proteins resulting in barrier impairment in the intestinal epithelium.
The role of charge recombination to spin-triplet excitons in non-fullerene acceptor organic solar cells
Creators: name: Gillett, Alexander J.
name: Privitera, Alberto
name: Dilmurat, Rishat
name: Karki, Akchheta
name: Qian, Deping
name: Pershin, Anton
name: Londi, Giacomo
name: Myers, William K.
name: Lee, Jaewon
name: Yuan, Jun
name: Ko, Seo-Jin
name: Riede, Moritz K.
name: Gao, Feng
name: Bazan, Guillermo C.
name: Rao, Akshay
name: Nguyen, Thuc-Quyen
name: Beljonne, David
name: Friend, Richard H.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Applied Physics (physics.app-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The power conversion efficiencies (PCEs) of organic solar cells (OSCs) using non-fullerene acceptors (NFAs) have now reached 18%. However, this is still lower than inorganic solar cells, for which PCEs >20% are commonplace. A key reason is that OSCs still show low open-circuit voltages (Voc) relative to their optical band gaps, attributed to non-radiative recombination. For OSCs to compete with inorganics in efficiency, all non-radiative loss pathways must be identified and where possible, removed. Here, we show that in most NFA OSCs, the majority of charge recombination at open-circuit proceeds via formation of non-emissive NFA triplet excitons (T1); in the benchmark PM6:Y6 blend, this fraction reaches 90%, contributing 60 mV to the reduction of Voc. We develop a new design to prevent recombination via this non-radiative channel through the engineering of significant hybridisation between the NFA T1 and the spin-triplet charge transfer exciton (3CTE). We model that the rate of the back charge transfer from 3CTE to T1 can be reduced by an order of magnitude, allowing re-dissociation of the 3CTE. We then demonstrate NFA systems where T1 formation is suppressed. This work therefore provides a clear design pathway for improved OSC performance to 20% PCE and beyond.
description: 30 pages, 3 figures, 1 table
title: The Beginning of Wisdom: Imagining fear in French Romanesque portal sculpture, c.1080-1140
Creators: name: Tame, Han
Publisher: name: University of Kent
Year: 2024

description: This thesis examines the role of fear in the design and function of Romanesque portal sculptures c.1090-1140 to understand how representations of the majestas Domini, Last Judgment and Hell were intended to guide their audiences towards an emotional state of terror and wonder that would lead to wisdom. It focuses on a small collection of important sites in Burgundy and the regions of Aveyron and Tarn-et-Garonne in south-western France to examine the development of monumental sculpture as a means of conveying and formulating theological concepts to lay and monastic audiences. Through an analysis of their iconography and composition in relation to exegetical and literary interpretations of divine majesty, judgment and eternal damnation, it offers new perspectives on pre-Scholastic art and thought, and contributes to current scholarship on affective devotion and emotional response in the context of Romanesque and Gothic sculpture. The new imagery created for the medium of portal sculpture is contextualised within the iconographic traditions which developed from Late Antiquity and continued to evolve over the early Middle Ages. 
The role of emotions, particularly fear, in the devotional cultures of the early twelfth century also presents new insights into the nature of visuality and spiritual sight in the Middle Ages. Portal sculptures were designed to prompt their audiences to develop the fearful attitude shared by the prophets, and which would remain even after the Last Judgment. Representations of response and the replication of divinely-created images encouraged those viewing the sculpture to imagine them as if they were real to participate in the visionary experience of the prophets or terror of the resurrected dead at the Last Judgment.
Infrared photometry of Cepheids in the LMC clusters NGC 1866 and NGC 2031
Creators: name: Testa, Vincenzo
name: Marconi, Marcella
name: Musella, Ilaria
name: Ripepi, Vincenzo
name: Dall'Ora, Massimo
name: Ferraro, Francesco R.
name: Mucciarelli, Alessio
name: Mateo, Mario
name: Cote', Patrick
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Near infrared (IR) studies of Cepheid variables in the LMC take advantage of the reduced light curve amplitude and metallicity dependence at these wavelengths. This work presents such photometry for two young clusters known to contain sizeable Cepheid populations: NGC 1866 and NGC 2031. Our goal is to determine light curves and period-luminosity (PL) relations in the near-IR, to assess the similarity between cluster and field pulsators, and to examine the predictive capability of current pulsation models. The light curves are obtained from multiwavelength broadband J,H,Ks photometry of Cepheids in both clusters, with periods previously established from optical photometry. Mean magnitudes for the Cepheids are used to construct PL relations in the near-IR. The properties in the PL planes are compared with the behavior of field Cepheids in the LMC and with the predictions of recent pulsational models, both canonical and overluminous. Cluster and field Cepheids are homogeneous and the inclusion of the cluster Cepheids in the field sample extends nicely the PL relation. The slope of the PL relation is constant over the whole period range and does not show -- at least in the adopted IR bands -- the break in slope at P ~ 10 d reported by some authors. A comparison with the predictions of pulsation models allows an estimate for the distance moduli of NGC 1866 and NGC 2031. The two clusters are found to lie at essentially the same distance. Fitting of theoretical models to the data gives, for the K filter, (m-M)_0 = 18.62+-0.10 if canonical models are used and (m-M)_0 = 18.42+-0.10 if overluminous models are used. On the basis of this result, some considerations on the relationship between the clusters and the internal structure of the LMC are presented.
description: Accepted for publication on Astronomy and Astrophysics. Full resolution figures available on request from the first author. Use bibtex, graphicx
Model error and sequential data assimilation. A deterministic formulation
Creators: name: Carrassi, A.
name: Vannitsem, S.
name: Nicolis, C.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Data assimilation schemes are confronted with the presence of model errors arising from the imperfect description of atmospheric dynamics. These errors are usually modeled on the basis of simple assumptions such as bias, white noise, first order Markov process. In the present work, a formulation of the sequential extended Kalman filter is proposed, based on recent findings on the universal deterministic behavior of model errors in deep contrast with previous approaches (Nicolis, 2004). This new scheme is applied in the context of a spatially distributed system proposed by Lorenz (1996). It is found that (i) for short times, the estimation error is accurately approximated by an evolution law in which the variance of the model error (assumed to be a deterministic process) evolves according to a quadratic law, in agreement with the theory. Moreover, the correlation with the initial condition error appears to play a secondary role in the short time dynamics of the estimation error covariance. (ii) The deterministic description of the model error evolution, incorporated into the classical extended Kalman filter equations, reveals that substantial improvements of the filter accuracy can be gained as compared with the classical white noise assumption. The universal, short time, quadratic law for the evolution of the model error covariance matrix seems very promising for modeling estimation error dynamics in sequential data assimilation.
Sectioning the tower: a mixed-use building exploration in downtown Vancouver
Creators: name: Furman, Andrew Derrick
Publisher: name: University of British Columbia
Year: 2009

description: The contemporary city is driven by private interests, leaving the public spaces as a weakly woven system. In such a system public space making is usually the left-over in the composition. By shaping the publicly accessible spaces through the section of the tower, a series of relationships of public/ private occur. Elevating the public ground throughout the city through remedial and new developments brings the public space to a more direct confrontation with the typology of the tower. The site chosen for this exploration of building and public space making is the municipal address of 900 Burrard St. in downtown Vancouver. The block already contains two existing buildings, which represent excellent regional examples of early Modernism; the former BC Electric Building and the Dal Grauer Substation. A programme of hotel, residences, office space, fitness club, cinema, and branch library generate specific scenarios around which the public space negotiates as transitional space.
Interaction of Thymine DNA Glycosylase with Oxidised 5-Methyl-cytosines in Their Amino- and Imino-Forms
Creators: name: Volkenandt, Senta
name: Beierlein, Frank
name: Imhof, Petra
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: thymine DNA glycosylase
subject: amino imino tautomers
subject: oxidised methyl-cytosine
subject: molecular dynamics simulations
subject: alchemical free energy calculations
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Thymine DNA Glycosylase (TDG) is an enzyme of the base excision repair mechanism and removes damaged or mispaired bases from DNA via hydrolysis of the glycosidic bond. Specificity is of high importance for such a glycosylase, so as to avoid the damage of intact DNA. Among the substrates reported for TDG are mispaired uracil and thymine but also formyl-cytosine and carboxyl-cytosine. Methyl-cytosine and hydroxylmethyl-cytosine are, in contrast, not processed by the TDG enzyme. We have in this work employed molecular dynamics simulations to explore the conformational dynamics of DNA carrying a formyl-cytosine or carboxyl-cytosine and compared those to DNA with the non-cognate bases methyl-cytosine and hydroxylmethyl-cytosine, as amino and imino tautomers. Whereas for the mispairs a wobble conformation is likely decisive for recognition, all amino tautomers of formyl-cytosine and carboxyl-cytosine exhibit the same Watson–Crick conformation, but all imino tautomers indeed form wobble pairs. The conformational dynamics of the amino tautomers in free DNA do not exhibit differences that could be exploited for recognition, and also complexation to the TDG enzyme does not induce any alteration that would indicate preferable binding to one or the other oxidised methyl-cytosine. The imino tautomers, in contrast, undergo a shift in the equilibrium between a closed and a more open, partially flipped state, towards the more open form upon complexation to the TDG enzyme. This stabilisation of the more open conformation is most pronounced for the non-cognate bases methyl-cytosine and hydroxyl-cytosine and is thus not a likely mode for recognition. Moreover, calculated binding affinities for the different forms indicate the imino forms to be less likely in the complexed DNA. These findings, together with the low probability of imino tautomers in free DNA and the indifference of the complexed amino tautomers, suggest that discrimination of the oxidised methyl-cytosines does not take place in the initial complex formation.