cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Analysis of DNA Double-Strand Break Repair Genes RAD50 and XRCC2 Using Zebrafish as the Model System
Creators: name: Stark, Alex William
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Oncology
subject: Genetics
subject: FOS: Biological sciences

description: DNA double-strand break (DSB) repair gene products play an important role in development and tumor suppression. Mutations in ATM, BRCA1, BRCA2, MRE11, NBN, PALB2, RAD50, RAD51, and XRCC2 result in embryonic lethality or cause pediatric diseases including ataxia-telangiectasia, Fanconi anemia (FA), Nijmegen breakage syndrome (NBS), and other disorders. A DNA DSB can be repaired using two different pathways: nonhomologous end-joining (NHEJ) and homology-directed DSB repair (HDR). Some DSB repair proteins, including ATM, Mre11, RAD50, and Nibrin, function in both pathways. RAD51 and its paralogs only function in HDR. Mre11-Rad50-Nibrin (MRN) complex is a heterohexamer composed of dimers of each protein. The MRN complex is important for early detection of DNA DSBs and activates downstream effectors, most notably the protein kinase ATM. ATM phosphorylates other DNA repair proteins including H2AX. H2AX, phosphorylated histone H2AX, is an important DNA damage signaling factor that helps recruit BRCA1 to damaged DNA. XRCC2 helps promote RAD51 foci through interaction with other RAD51 paralogs RAD51B, RAD51C, and RAD51D to form the BCDX2 complex. FA and NBS-like disorder result from biallelic mutations in XRCC2 and RAD50, respectively. These genetically distinct disorders share many clinical similarities. Bone marrow failure is a key symptom of FA and has been observed in multiple NBS patients. The hematopoietic malignancy acute myeloid leukemia has been observed in patients suffering from FA and NBS. Hormone abnormalities and fertility issues present in both patient populations as do issues with growth and development. Null mutations in RAD50 and XRCC2 are embryonic lethal in humans and mice, so zebrafish was chosen as the model organism to study mutations in each of these genes. Null mutations in related genes (e.g., BRCA2) that result in embryonic lethality in humans and mice are tolerated in zebrafish. Frameshift mutations were generated in rad50 and xrcc2 using transcription activator-like effector nucleases in zebrafish. We recovered the first viable vertebrate model for biallelic null mutations in RAD50 and XRCC2. Study of these mutants might offer unique insights into human disease that have not been possible previously due to a lack of appropriate model systems.
Entanglement and dynamical phase transition in a spin-orbit-coupled Bose-Einstein condensate
Creators: name: Sun, F. X.
name: Zhang, W.
name: He, Q. Y.
name: Gong, Q. H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Characterizing quantum phase transitions through quantum correlations has been deeply developed for a long time, while the connections between dynamical phase transitions (DPTs) and quantum entanglement is not yet well understood. In this work, we show that the time-averaged two-mode entanglement in the spin space reaches a maximal value when it undergoes a DPT induced by external perturbation in a spin-orbit-coupled Bose-Einstein condensate. We employ the von Neumann entropy and a correlation-based entanglement criterion as entanglement measures and find that both of them can infer the existence of DPT. While the von Neumann entropy works only for a pure state at zero temperature and requires state tomography to reconstruct, the experimentally more feasible correlation-based entanglement criterion acts as an excellent proxy for entropic entanglement and can determine the existence of entanglement for a mixed state at finite temperature, making itself an excellent indicator for DPT. Our work provides a deeper understanding about the connection between DPTs and quantum entanglement, and may allow the detection of DPT via entanglement become accessible as the examined criterion is suitable for measuring entanglement.
description: 9 pages, 6 figures
Entanglement sharing: from qubits to Gaussian states
Creators: name: Adesso, Gerardo
name: Illuminati, Fabrizio
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: Mathematical Physics (math-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: It is a central trait of quantum information theory that there exist limitations to the free sharing of quantum correlations among multiple parties. Such 'monogamy constraints' have been introduced in a landmark paper by Coffman, Kundu and Wootters, who derived a quantitative inequality expressing a trade-off between the couplewise and the genuine tripartite entanglement for states of three qubits. Since then, a lot of efforts have been devoted to the investigation of distributed entanglement in multipartite quantum systems. In these proceedings we report, in a unifying framework, a bird's eye view of the most relevant results that have been established so far on entanglement sharing in quantum systems. We will take off from the domain of N qubits, graze qudits, and finally land in the almost unexplored territory of multimode Gaussian states of continuous variable systems.
description: 11 pages. Proceedings of the workshop "Entanglement in physical and information sciences", Centro Ennio de Giorgi, Pisa, December 2004. (v2) References updated, final version published in Int. J. Quant. Inf
Analysis of the Physiological Roles of the Nonsense Mediated mRNA Decay Pathway in Drosophila Melanogaster
Creators: name: Chapin, Alex
Publisher: name: University of Utah
Year: 2019

description: The nonsense mediated mRNA decay (NMD) pathway is a conserved posttranscriptional mRNA decay pathway that functions to destabilize a variety of naturally occurring target mRNAs. The NMD pathway functions in all eukaryotes and regulates a significant portion of the transcriptome. It is thought that this regulation is critical as inhibition of NMD leads to physiological and developmental defects in all organisms and in the case of more complex organisms, lethality. It is predicted that overexpression of NMD pathway target genes leads to these defects in NMD mutants. Despite the critical nature of this pathway, little is know about how NMD functions in a developmental and physiological context, including which target genes are most critically regulated by NMD and how the overexpression of these targets may mediate the NMD mutant phenotype. To address this knowledge gap, we first use two genome-wide techniques to identify and characterize the kinds of transcripts targeted by NMD in the context of an intact metazoan, Drosophila melanogaster. We then examine more closely the function of one of these target genes, Gadd45, and find that overexpression of this target in NMD mutants may explain important aspects of the NMD mutant phenotype.
STAR results on longitudinal spin dynamics
Creators: name: Kiryluk, Joanna
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present preliminary results on the double longitudinal spin asymmetries A_LL in inclusive jet production and the longitudinal spin transfer asymmetries D_LL in inclusive Lambda and anti-Lambda hyperon production. The data amount to about 0.5 pb-1 collected at RHIC in 2003 and 2004 with beam polarizations up to 45 %. The jet A_LL asymmetries, measured over 5 < pT < 17 GeV/c, are consistent with evaluations based on deep-inelastic scattering parametrizations for the gluon polarization in the nucleon, and disfavor large positive values of gluon polarization in the nucleon. The Lambda and anti-Lambda D_LL, measured at midrapidity and at low average transverse momentum of 1.5 GeV/c, are consistent with zero within their dominant statistical uncertainties.
description: 4 pages, 2 figures, presented at XIV International Workshop on Deep Inelastic Scattering (DIS2006), Tsukuba, Japan, 20-24 April 2006
A linearized stability theorem for nonlinear delay fractional differential equations
Creators: name: Tuan, Hoang The
name: Trinh, Hieu
Publisher: name: arXiv
Year: 2017
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: Asymptotic stability, delay differential equations with fractional derivatives, fractional differential equations, growth and boundedness, stability

description: In this paper, we prove a theorem of linearized asymptotic stability for fractional differential equations with a time delay. More precisely, using the method of linearization of a nonlinear equation along an orbit (Lyapunov's first method), we show that an equilibrium of a nonlinear Caputo fractional differential equation with a time delay is asymptotically stable if its linearization at the equilibrium is asymptotically stable. Our approach based on a technique which converts the linear part of the equation into a diagonal one. Then using properties of generalized Mittag-Leffler functions, the construction of an associated Lyapunov--Perron operator and the Banach contraction mapping theorem, we obtain the desired result.
Genomic head to head telomeric sequences detection by one PCR
Creators: name: Pommier, Jean-Patrick
Publisher: name: Zenodo
Year: 2025

description: This article initially posted on https://dip4fish.blogspot.com/search?q=genomic in 2012, describes preliminary results obtained by PCR in order to detect head to head telomeric  sequences in human genome possibly resulting of dicentric chromosomes formation in senescing primary fibroblasts or in SV40 transformed fibroblasts.
Synthesis and evaluation of novel spiro derivatives for pyrrolopyrimidines as anti-hyperglycemia promising compounds
Creators: name: Fatahala, Samar Said
name: Shahenda Mahgub
name: Taha, Heba
name: Hameed, Rania Helmy Abd-El
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Pyrrolopyrimidin-4-ylidene-malononitriles IIa–d were prepared as important intermediates for preparation of a new series of spiro-pyrrolopyrimidines. These intermediates undergo cyclisation via reaction with acetylacetone, guanidine hydrochloride or hydrazine hydrate. Elemental and spectroscopic evidences for the structures of these compounds are presented. The final compounds have been monitored for in vivo anti-hyperglycemic activity, compared with Amaryl as standard drug. Among 12 tested compounds, both spiro (pyrano IIIb and pyrazlo Va) derivatives exhibit promising anti-hyperglycemic activity.
Neutron imaging and tomography with MCPs
Creators: name: Pinto, Serge Duarte
name: Ortega, Raquel
name: Ritzau, Steve
name: Pasquale, David
name: Laprade, Bruce
name: Mrotek, Sharon
name: Gardell, Sean
name: Zhou, Zhou
name: Plomp, Jeroen
name: van Eijck, Lambert
name: Bilheux, Hassina
name: Dhiman, Indu
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: A neutron imaging detector based on neutron-sensitive microchannel plates (MCPs) was constructed and tested at beamlines of thermal and cold neutrons. The MCPs are made of a glass mixture containing B-10 and natural Gd, which makes the bulk of the MCP an efficient neutron converter. Contrary to the neutron sensitive scintillator screens normally used in neutron imaging, spatial resolution is not traded off with detection efficiency. While the best neutron imaging scintillators have a detection efficiency around a percent, a detection efficiency of around 50% for thermal neutrons and 70% for cold neutrons has been demonstrated with these MCPs earlier. Our tests show a performance similar to conventional neutron imaging detectors, apart from the orders of magnitude better sensitivity. We demonstrate a spatial resolution better than 150 um. The sensitivity of this detector allows fast tomography and neutron video recording, and will make smaller reactor sites and even portable sources suitable for neutron imaging.
description: Submitted to the proceedings of the 19th International Workshop on Radiation Imaging Detectors (iWoRiD) 2-6 July 2017, Krakow, Poland
Black Hole Horizon Fluctuations
Creators: name: Casher, A.
name: Englert, F.
name: Itzhaki, N.
name: Massar, S.
name: Parentani, R.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It is generally admitted that gravitational interactions become large at an invariant distance of order $1$ from the black hole horizon. We show that due to the ``atmosphere'' of high angular particles near the horizon strong gravitational interactions already occur at an invariant distance of the order of $\sqrt[3]{M}$. The implications of these results for the origin of black hole radiation, the meaning of black hole entropy and the information puzzle are discussed.
description: Latex, 22 pages (minor corrections and precisions added)
Any Way You Want It: Pushing the Limits of Chemical Protein Synthesis
Creators: name: Jacobsen, Michael Thomas
Publisher: name: University of Utah
Year: 2019

description: Chemical protein synthesis, via solid-phase peptide synthesis and chemoselective ligation of peptides, is a powerful approach for preparing peptides and proteins. These techniques enable complete atomic control over protein composition with both mechanistic and practical applications for biochemistry. The foundation of this dissertation is formed by two ambitious chemical protein synthesis projects: DapA (Chapter 2) and Dpo4 (Chapter 5). DapA is a 312-residue protein whose folding depends on the well-studied chaperone GroEL/ES. The successful synthesis of DapA (in both L- and D- chirality) was used to demonstrate cross-chiral folding by GroEL/ES-a fundamental biological insight and potential tool for future mirror-image synthetic biology research. However, the record-breaking synthesis of DapA was an arduous process requiring tremendous human and technical resources. The lessons from this project were then applied to the synthesis of our next target, Dpo4 (352 residues). Dpo4 is one of the shortest DNA/RNA polymerases, providing an accessible synthetic tool to amplify DNA/RNA for future synthetic biology studies. A new concept termed DOPPEL (Diversity-based Optimization of Peptide Properties to Enhance Ligations) was used to simplify this synthesis. Furthermore, various synthesis strategies and general advice for completing ! ! iv mega-synthesis projects in the future are detailed in this chapter. In both the DapA and Dpo4 projects, one of the most prominent challenges was the handling of poorly soluble peptide segments. These poorly soluble peptides can lead to dramatic yield losses and additional complexities. In the third major synthesis project of this thesis, GroES, we overcame an even greater insolubility challenge. This 97-residue protein could not be synthesized due to extreme solubility challenges with its C-terminal half. In response to this challenge, a new chemical tool was developed to link a solubilizing peptide ("Helping Hand") to the C-terminal half of the protein. Key to this approach is a new synthetic building block, Fmoc-Ddae-OH, which is easy to synthesize, incorporate, and cleanly remove once the solubilizing function is complete. Overall, this dissertation pushes the limits of chemical peptide and protein synthesis, and provides exciting directions for the next wave of biochemists looking to use chemical protein synthesis to study interesting problems and engineering challenges.
A Study of Fermi-LAT GeV gamma-ray Emission towards the Magnetar-harboring Supernova Remnant Kesteven 73 and Its Molecular Environment
Creators: name: Liu, Bing
name: Chen, Yang
name: Zhang, Xiao
name: Liu, Qian-Cheng
name: He, Ting-Lan
name: Zhou, Xin
name: Zhou, Ping
name: Su, Yang
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report our independent GeV gamma-ray study of the young shell-type supernova remnant (SNR) Kes 73 which harbors a central magnetar, and CO-line millimeter observations toward the SNR. Using 7.6 years of Fermi-LAT observation data, we detected an extended gamma-ray source ("source A") with the centroid on the west of the SNR, with a significance of 21.6 sigma in 0.1-300 GeV and an error circle of 5.4 arcminute in angular radius. The gamma-ray spectrum cannot be reproduced by a pure leptonic emission or a pure emission from the magnetar, and thus a hadronic emission component is needed. The CO-line observations reveal a molecular cloud (MC) at V_LSR~90 km/s, which demonstrates morphological correspondence with the western boundary of the SNR brightened in multiwavelength. The 12CO (J=2-1)/12CO (J=1-0) ratio in the left (blue) wing 85-88 km/s is prominently elevated to ~1.1 along the northwestern boundary, providing kinematic evidence of the SNR-MC interaction. This SNR-MC association yields a kinematic distance 9 kpc to Kes 73. The MC is shown to be capable of accounting for the hadronic gamma-ray emission component. The gamma-ray spectrum can be interpreted with a pure hadronic emission or a magnetar+hadronic hybrid emission. In the case of pure hadronic emission, the spectral index of the protons is 2.4, very similar to that of the radio-emitting electrons, essentially consistent with the diffusive shock acceleration theory. In the case of magnetar+hadronic hybrid emission, a magnetic field decay rate >= 10^36 erg/s is needed to power the magnetar's curvature radiation.
description: 7 figures, published in ApJ
Quantum Computation via Sparse Distributed Representation
Creators: name: Rinkus, Gerard J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Quantum superposition says that any physical system simultaneously exists in all of its possible states, the number of which is exponential in the number of entities composing the system. The strength of presence of each possible state in the superposition, i.e., its probability of being observed, is represented by its probability amplitude coefficient. The assumption that these coefficients must be represented physically disjointly from each other, i.e., localistically, is nearly universal in the quantum theory/computing literature. Alternatively, these coefficients can be represented using sparse distributed representations (SDR), wherein each coefficient is represented by small subset of an overall population of units, and the subsets can overlap. Specifically, I consider an SDR model in which the overall population consists of Q WTA clusters, each with K binary units. Each coefficient is represented by a set of Q units, one per cluster. Thus, K^Q coefficients can be represented with KQ units. Thus, the particular world state, X, whose coefficient's representation, R(X), is the set of Q units active at time t has the max probability and the probability of every other state, Y_i, at time t, is measured by R(Y_i)'s intersection with R(X). Thus, R(X) simultaneously represents both the particular state, X, and the probability distribution over all states. Thus, set intersection may be used to classically implement quantum superposition. If algorithms exist for which the time it takes to store (learn) new representations and to find the closest-matching stored representation (probabilistic inference) remains constant as additional representations are stored, this meets the criterion of quantum computing. Such an algorithm has already been described: it achieves this "quantum speed-up" without esoteric hardware, and in fact, on a single-processor, classical (Von Neumann) computer.
description: 5 pages, 2 figs
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0324
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0324, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0324, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: http://www.wikidata.org/entity/Q15945019
description: Provenance: abbaye Saint-Étienne de Dijon
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00416
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00416, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Adventures of the Coupled Yang-Mills Oscillators: I. Semiclassical Expansion
Creators: name: Matinyan, Sergei G.
name: Müller, Berndt
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We study the quantum mechanical motion in the $x^2y^2$ potentials with $n=2,3$, which arise in the spatially homogeneous limit of the Yang-Mills (YM) equations. These systems show strong stochasticity in the classical limit ($\hbar = 0$) and exhibit a quantum mechanical confinement feature. We calculate the partition function $Z(t)$ going beyond the Thomas-Fermi (TF) approximation by means of the semiclassical expansion using the Wigner-Kirkwood (WK) method. We derive a novel compact form of the differential equation for the WK function. After separating the motion in the channels of the equipotential surface from the motion in the central region, we show that the leading higher-order corrections to the TF term vanish up to eighth order in $\hbar$, if we treat the quantum motion in the hyperbolic channels correctly by adiabatic separation of the degrees of freedom. Finally, we obtain an asymptotic expansion of the partition function in terms of the parameter $g^2\hbar^4t^3$.
Auditing the use of LOINC® to support interoperability across three large institutions
Creators: name: Lin, Ming-Chin
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Information Technology
subject: Bioinformatics
subject: FOS: Computer and information sciences

description: Logical Observation Identifiers Names and Codes (LOINC®) was developed in 1994 to provide a universal vocabulary for reporting laboratory and clinical observations. This dissertation was aimed at determining whether LOINC is meeting its goal when it is used in the real world. Three institutions, Associated and Regional University Pathologist (ARUP), Intermountain Healthcare, and Regenstrief Institute, were invited to participate in this research. These institutions represented three of the seven institutions that provided their catalogue of laboratory test names for creating the first version of laboratory LOINC codes. After obtaining IRB approval, each institution provided 5 years (2003-2007) of laboratory data and their associated local codes and LOINC code mappings. Extensional definitions (EDs) were used to characterize the laboratory data reported by a specific LOINC code. EDs included frequency of testing, mean and standard deviation of the result values, coded variables, etc. To reduce privacy concerns, we distributed parsing and processing programs to each institution and the initial processing of the raw results occurred within the local systems, and only the deidentified EDs were sent to the primary investigator for combined analysis. We used the EDs to evaluate the coverage, correctness, consistency and competence of LOINC. For coverage, we analyzed how many laboratory tests being routinely tested in daily operations could be assigned a correct LOINC code. For correctness, we verified the accuracy of LOINC mappings to local codes. For consistency and usefulness, we detected any inconsistencies in LOINC design and measured the degree of semantic interoperability that could be achieved using LOINC. Besides auditing LOINC code use, we also analyzed the result values that were associated with the LOINC results (i.e. characteristics like the type of result (number, coded value), units of measure, answer set (positive/negative) etc.). We also found that consistent use of result values was important in achieving semantic interoperability when exchanging laboratory data. Our analysis produced the following results: 1. Completeness: LOINC can provide 99% coverage rate for the results in two typical health care institutions and 79% coverage for results from a reference laboratory. 2. Correctness: An error rate of 4.5% existed in mappings at the three institutions. 3. Consistency and usefulness: Several complicated or inconsistent designs for LOINC usage were found, which reduced the semantic interoperability of LOINC.
Additional file 4 of Transcriptome-wide 5-methylcytosine modification profiling of long non-coding RNAs in A549 cells infected with H1N1 influenza A virus
Creators: name: Jiang, Shengqiang
name: Hu, Jing
name: Bai, Yang
name: Hao, Ruiwei
name: Liu, Long
name: Chen, Hongying
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 4
Decay of solutions to parabolic-type problem with distributed order Caputo derivative
Creators: name: Kubica, Adam
name: Ryszewska, Katarzyna
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35R13, 35K45, 26A33, 34A08

description: We consider the decay of solution to fractional diffusion equation with the distributed order Caputo derivative. We assume that the elliptic operator is time-dependent and that the weight function contained in the definition of the distributed order Caputo derivative is just integrable. We establish the relation between behavior of weight function near zero and the decay rate of solution.
Matter and cosmogenesis in Kant's Theory of the Heavens
Creators: name: Benoit, Garance
Publisher: name: arXiv
Year: 2024
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: In 1755, Kant published his General Natural History and Theory of the Heavens, in which he presented his hypothesis on the formation of the solar system, known as the primitive nebula hypothesis. This original theory of the heavens was written in dialogue with the conceptions of celestial matter of his time. On the one hand, Kant recognized Descartes' cosmological enterprise as a decisive mechanistic requirement for the intelligence of physics, but his vortices of matter fell into disrepute: Newton invalidated them mathematically. On the other hand, attraction at a distance provides an incomparable explanation of phenomena, but has left a gaping hole in our understanding of the law's material anchorage in bodies, and ultimately sends the question of how the system works back to God. He then set out to overcome the dichotomy established by these two authors, drawing on the Cartesian adage ''give me matter and I'll make a world'', but applying Newton's laws to cosmogenesis. In concrete terms, interplanetary space currently contains no matter capable of explaining the motion of the stars, we need to look further back into the system's past, to find an earlier state of material dispersion whose effects are still being felt. He must assume the existence of a cloud of dust, made up of the simplest elements and moved by the forces of attraction and repulsion alone. From this, Kant can form the hypothesis of the primitive nebula breaking down first into a phase of stellogenesis, and then into the creation of an accretion disk gradually forming the planets and their satellites.
Supplementary Methods and Figures S1 - S4 from Induced expression of a vestigial sexual signal
Creators: name: Gray, David A.
name: Scherezade Hormozi
name: Libby, Fritz R.
name: Cohen, Randy W.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Vestigial morphological traits are common and well known in a variety of taxa. Identification of vestigial genes has illustrated the potential for evolutionary reversals and the re-expression of atavistic traits. Here we induce expression of a behavioural sexual signal, male calling song, in a cricket species, Gryllus ovisopis, which lacks a functional calling song. We successfully used acetylcholine injections in the frontal space of the head of male crickets to activate cerebral command neurons for cricket calling, and we recorded calling songs with a temporal chirp pattern similar to that of G. ovisopis' close evolutionary relatives, G. firmus and G. pennsylvanicus, implying that the neural pattern generators which underlie cricket calling behaviour persist in a vestigial state in G. ovisopis. To our knowledge, this is the first demonstration of the induced expression of a vestigial behaviour in any organism. The retention of latent neural capacity to express sexual behaviours could have important implications for rapid evolution, trait re-emergence and reproductive isolation.
The Association of Physical Activity Knowledge, Nutrition Knowledge, and Physical Activity Enjoyment in Low Socioeconomic Elementary School Children
Creators: name: Mattson, Rose Elise
Publisher: name: University of Utah
Year: 2019
Subjects: Physical education
Nutrition

description: According to the Centers for Disease Control (CDC), 17% of children and adolescents ages 2-19 are obese. The prevalence of childhood obesity is higher in minority and low sociodemographic (SES) populations. Comprehensive nutrition and physical activity interventions have resulted in reductions in childhood obesity. The purpose of this study was to explore the change in physical activity knowledge, nutrition knowledge, and physical activity enjoyment scores in low socioeconomic elementary schools during a Comprehensive Physical Activity Program (CSPAP). Secondly, associations between physical activity enjoyment scores and nutrition knowledge were analyzed. The study populations were 504 and 800 elementary school children, in grades 3-6, from five Title I schools in the Salt Lake City River District. Students completed three assessments: a physical activity knowledge assessment, a nutrition knowledge survey, and the physical activity enjoyment scale (PACES) test that were administered during the school hours. Using data from the 2015-2016 school year, the change in physical activity knowledge, nutrition knowledge, and PACES scores was assessed using three-factor 4 x 2 x 2 mixed-design ANOVA tests. The association between the nutrition knowledge and PACES scores was evaluated using Pearson's correlation coefficients. Physical activity knowledge scores increased from pretest (0.26 ± 0.11) to posttest (0.28± 0.12) significantly ( p=0.05) during the intervention. Additionally, PACES scores increased from pretest (36.84 ± 15. 14) to posttest (39.34 ± 14.79) significantly (p=0.02), during the intervention. Lastly, higher nutrition knowledge scores were significantly correlated with higher PACES scores (r=0.08; p= 0.02). These results emphasize the importance of providing physical activity and nutrition education for ethnic minority low SES elementary school children. Moreover, these findings demonstrate that improvements in physical activity enjoyment can occur during a school-based intervention. Increases in physical activity enjoyment and knowledge may translate to increases in chronic physical activity and improve children's health outcomes.
title: Avant-propos_Nouveau manuel complet de l'accordeur et du réparateur de pianos
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Avant-propos
description: ID_PARA_00892
Kaluza-Klein Dark Matter and Galactic Antiprotons
Creators: name: Barrau, Aurelien
name: Salati, Pierre
name: Servant, Geraldine
name: Donato, Fiorenza
name: Grain, Julien
name: Maurin, David
name: Taillet, Richard
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Extra dimensions offer new ways to address long-standing problems in beyond the standard model particle physics. In some classes of extra-dimensional models, the lightest Kaluza-Klein particle is a viable dark matter candidate. In this work, we study indirect detection of Kaluza-Klein dark matter via its annihilation into antiprotons. We use a sophisticated galactic cosmic ray diffusion model whose parameters are fully constrained by an extensive set of experimental data. We discuss how fluxes of cosmic antiprotons can be used to exclude low Kaluza-Klein masses.
description: 14 pages, 7 figures, 3 tables
On Aspects and Implications of the New Covariant 4D, N = 1 Green-Schwarz Sigma-model Action
Creators: name: Gates, S. J.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Utilizing (2,0) superfields, we write a supersymmetry-squared action and partially relate it to the new formulation of the Green-Schwarz action given by Berkovits and Siegel. Recent results derived from this new formulation are discussed within the context of some prior proposals in the literature. Among these, we note that 4D, N = 1 beta-FFC superspace geometry with a composite connection for R-symmetry has now been confirmed as the only presently known limit of 4D, N = 1 heterotic string theory that is derivable in a completely rigorous manner.
description: 15 pages, LaTeX
Models for Storage in Database Backends
Creators: name: Schiebelbein, Edgard
name: Hatia, Saalik
name: Bieniusa, Annette
name: Petri, Gustavo
name: Ferreira, Carla
name: Shapiro, Marc
Publisher: name: arXiv
Year: 2024
Subjects: subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: This paper describes ongoing work on developing a formal specification of a database backend. We present the formalisation of the expected behaviour of a basic transactional system that calls into a simple store API, and instantiate in two semantic models. The first one is a map-based, classical versioned key-value store; the second one, journal-based, appends individual transaction effects to a journal. We formalise a significant part of the specification in the Coq proof assistant. This work will form the basis for a formalisation of a full-fledged backend store with features such as caching or write-ahead logging, as variations on maps and journals.
description: Workshop on Principles and Practice of Consistency for Distributed Data (PaPoC), EuroSys (ACM), Apr 2024, Ath{\`e}nes, Greece
Replica Field Theory for a Generalized Franz--Parisi Potential of Inhomogeneous Glassy Systems: New Closure and the Associated Self-Consistent Equation
Creators: name: Frusawa, Hiroshi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: On approaching the dynamical transition temperature, supercooled liquids show heterogeneity over space and time. Static replica theory investigates the dynamical crossover in terms of the free energy landscape (FEL). Two kinds of static approaches have provided a self-consistent equation for determining this crossover, similar to the mode coupling theory for glassy dynamics. One uses the Morita-Hiroike formalism of the liquid state theory, whereas the other relies on the density functional theory (DFT). Each of the two approaches has advantages in terms of perturbative field theory. Here, we develop a replica field theory that has the benefits from both formulations. We introduce the generalized Franz-Parisi potential to formulate a correlation functional. Considering fluctuations around an inhomogeneous density determined by the Ramakrishnan--Yussouf DFT, we find a new closure as the stability condition of the correlation functional. The closure leads to the self-consistent equation involving the triplet direct correlation function. The present field theory further helps us study the FEL beyond the mean-field approximation.
description: 27 pages, 2 figures
Angiopoietin-2 level as a tool for cardiovascular risk stratification in hypertensive type 2 diabetic subjects
Creators: name: Siddiqui, Khalid
name: Salini Scaria Joy
name: Shaik Sarfaraz Nawaz
name: Otaibi, Mohammad T. Al
name: Al-Rubeaan, Khalid
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy

description: Objectives: This observational cross-sectional study aimed to investigate the relationship between serum Angiopoietin-2 (Ang-2) levels and cardiovascular (CVD) risk factors in drug controlled hypertensive diabetic subjects without cardiovascular complications. Methods: All subjects were evaluated for fasting blood glucose (FBG), HbA1c, liver enzymes, lipid profile and serum Ang-2. Results: Mean serum Ang-2 level was significantly higher in hypertensive diabetic subjects. In bivariate analysis in diabetic subjects with cardiovascular risk factors, Ang-2 positively correlated with waist circumference, body mass index (BMI), systolic blood pressure (SBP), FBG, HbA1c and triglycerides. In multivariate linear regression analysis, this association remained significant with FBG and triglycerides. Ang-2 levels were independently associated with CVD risk factors in drug controlled Type 2 diabetes (T2D) subjects. Conclusions: Further detailed studies in larger population with more attention is needed to consider Ang-2 level as a tool for CVD risk stratification in hypertensive diabetic subjects.
title: 01_1837
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Three-body Unitarity in the Finite Volume
Creators: name: Mai, M.
name: Döring, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The physical interpretation of lattice QCD simulations, performed in a small volume, requires an extrapolation to the infinite volume. A method is proposed to perform such an extrapolation for three interacting particles at energies above threshold. For this, a recently formulated relativistic $3\to 3$ amplitude based on the isobar formulation is adapted to the finite volume. The guiding principle is two- and three-body unitarity that imposes the imaginary parts of the amplitude in the infinite volume. In turn, these imaginary parts dictate the leading power-law finite-volume effects. It is demonstrated that finite-volume poles arising from the singular interaction, from the external two-body sub-amplitudes, and from the disconnected topology cancel exactly leaving only the genuine three-body eigenvalues. The corresponding quantization condition is derived for the case of three identical scalar-isoscalar particles and its numerical implementation is demonstrated.
description: 9 pages, 3 figures
Measuring the primordial power spectrum: Principal component analysis of the cosmic microwave background
Creators: name: Leach, Samuel
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We implement and investigate a method for measuring departures from scale-invariance, both scale-dependent as well as scale-free, in the primordial power spectrum of density perturbations using cosmic microwave background (CMB) C_l data and a principal component analysis technique. The primordial power spectrum is decomposed into a dominant scale-invariant Gaussian adiabatic component plus a series of orthonormal modes whose detailed form only depends the noise model for a particular CMB experiment. However, in general these modes are localised across wavenumbers with 0.01 < k < 0.2 Mpc^-1, displaying rapid oscillations on scales corresponding the acoustic peaks where the sensitivity to primordial power spectrum is greatest. The performance of this method is assessed using simulated data for the Planck satellite, and the full cosmological plus power spectrum parameter space is integrated out using Markov Chain Monte Carlo. As a proof of concept we apply this data compression technique to the current CMB data from WMAP, ACBAR, CBI and VSA. We find no evidence for the breaking of scale-invariance from measurements of four PCA mode amplitudes, which is translated to a constraint on the scalar spectral index n_S(k_0=0.04 Mpc^-1)=0.94+-0.04 in accordance with WMAP studies.
description: 9 pages with 13 figures. MNRAS accepted version
Hydrodynamic predictions for 5.44 TeV Xe+Xe collisions
Creators: name: Giacalone, Giuliano
name: Noronha-Hostler, Jacquelyn
name: Luzum, Matthew
name: Ollitrault, Jean-Yves
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We argue that relativistic hydrodynamics is able to make robust predictions for soft particle production in Xe+Xe collisions at the CERN Large Hadron Collider (LHC). The change of system size from Pb+Pb to Xe+Xe provides a unique opportunity to test the scaling laws inherent to fluid dynamics. Using event-by-event hydrodynamic simulations, we make quantitative predictions for several observables: mean transverse momentum, anisotropic flow coefficients, and their fluctuations. Results are shown as function of collision centrality.
description: 10 pages, 5 figures; v2: now with deformed Xe nuclei
A Canticle on (4,0) Supergravity-Scalar Multiplet Systems for a ``Cognoscente''
Creators: name: Dhanawittayapol, R.
name: Gates, S. James
name: Rana, Lubna
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Extending prior investigations, we study three of the the four distinct minimal (4,0) scalar multiplets coupled to (4,0) supergravity. It is found that the scalar multiplets manifest their differences at the component level by possessing totally different couplings to the supergravity fields. Only the SM-I multiplet possesses a conformal coupling. For the remaining multiplets, terms linear in the world sheet curvature and/or SU(2) gauge field strengths are required to appear in the action by local supersymmetry.
description: 14, LaTeX file