cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Spicing up continuum solvation models with SaLSA: the spherically-averaged liquid susceptibility ansatz
Creators: name: Sundararaman, Ravishankar
name: Schwarz, Kathleen A.
name: Letchworth-Weaver, Kendra
name: Arias, T. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Continuum solvation models enable electronic structure calculations of systems in liquid environments, but because of the large number of empirical parameters, they are limited to the class of systems in their fit set (typically organic molecules). Here, we derive a solvation model with no empirical parameters for the dielectric response by taking the linear response limit of a classical density functional for molecular liquids. This model directly incorporates the nonlocal dielectric response of the liquid using an angular momentum expansion, and with a single fit parameter for dispersion contributions it predicts solvation energies of neutral molecules with an RMS error of 1.3 kcal/mol in water and 0.8 kcal/mol in chloroform and carbon tetrachloride. We show that this model is more accurate for strongly polar and charged systems than previous solvation models because of the parameter-free electric response, and demonstrate its suitability for ab initio solvation, including self-consistent solvation in quantum Monte Carlo calculations.
description: 5 pages, 4 figures
Molecular basis of cardiomiopathy
Creators: name: Pecoraro, Michela
Publisher: name: Universita degli studi di Salerno
Year: 2018
Subjects: subject: BIO/14 FARMACOLOGIA
subject: Hypoxia
subject: Connexin 43
subject: Cardiotoxicity

description: 2016 - 2017
description: The normal heart rhythm is guaranteed by an important intercellular junctions system, named Gap Junction (GJs). Each GJs consists of two units called connexons formed by six specific trans-membrane proteins named connexins (Cx). Recent reports suggest the presence of Cx43 in the inner mitochondrial membrane where it plays an important cardioprotection mechanism. Alterations in Cx43 expression and distribution were observed in several myocardium disease; i.e. in hypertrophic cardiomyopathy, heart failure and ischemia. Thus, in this doctoral study, we investigated the role of Cx43, and in particular of mitochondrial Cx43, in different cardiomyopaties models... [edited by Author]
title: Postoperative imaging of the elbow
Creators: name: Cerezal, Luis
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Musculoskeletal joint
subject: Bones
subject: MR
subject: CT
subject: Ultrasound
subject: Surgery
subject: Diagnostic procedure
subject: Trauma

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Review the main surgical techniques in the treatment of elbow injuries. 2. Describe the main complications related to surgical techniques. 3. To review image findings and role of different imaging techniques in the postoperative...
Additional file 1 of CD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice
Creators: name: Aguilera-Braico, Diego Maximo
name: Balogh, Gabriela A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology

description: Additional file 1: Table S1. CD3Ɛ FITC labelled cell population in lymph node and spleen from BALBc mice
title: Renal lithiasis and Fatty Liver Disease, is there any relationship?
Creators: name: ARIAS, CARLOS
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Developmental disease

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Hepatic steatosis or fatty liver disease, defined as fat within the liver. Is a reversible and benign condition, secundary to a metabolic stress of many origins. (1) On the other hand, non alcoholic fatty liver disease (NAFLD) is a given term to...
Evaluation of Enhanced Security Solutions in 802.11-Based Networks
Creators: name: Ajah, Ifeyinwa Angela
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Traditionally, 802.11-based networks that relied on wired equivalent protocol (WEP) were especially vulnerable to packet sniffing. Today, wireless networks are more prolific, and the monitoring devices used to find them are mobile and easy to access. Securing wireless networks can be difficult because these networks consist of radio transmitters and receivers, and anybody can listen, capture data and attempt to compromise it. In recent years, a range of technologies and mechanisms have helped make networking more secure. This paper holistically evaluated various enhanced protocols proposed to solve WEP related authentication, confidentiality and integrity problems. It discovered that strength of each solution depends on how well the encryption, authentication and integrity techniques work. The work suggested using a Defence-in-Depth Strategy and integration of biometric solution in 802.11i. Comprehensive in-depth comparative analysis of each of the security mechanisms is driven by review of related work in WLAN security solutions.
description: The paper holistically surveyed and evaluated the outcome of past researches on security protocols; 802.1X, WPA, WPA2 ,in juxtaposition to VPN SSL, and VPN IPsec. It discovered that strength of each solution depends on how well the encryption, authentication and integrity techniques work. The work suggested using a Defence-in-Depth Strategy and integration of biometric solution in 802.11i
Spinning like a Blue Straggler: the population of fast rotating Blue Straggler stars in Omega Centauri
Creators: name: Mucciarelli, A.
name: Lovisi, L.
name: Ferraro, F. R.
name: Dalessandro, E.
name: Lanzoni, B.
name: Monaco, L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: By using high-resolution spectra acquired with FLAMES-GIRAFFE at the ESO/VLT, we measured radial and rotational velocities for 110 Blue Straggler stars (BSSs) in Omega Centauri, the globular cluster-like stellar system harboring the largest known BSS population. According to their radial velocities, 109 BSSs are members of the system. The rotational velocity distribution is very broad, with the bulk of BSSs spinning at less than ~40 km/s (in agreement with the majority of such stars observed in other globular clusters) and a long tail reaching ~200 km/s. About 40% of the sample has vsini >40 km/s and about 20% has vsini >70 km/s. Such a large fraction is very similar to the percentage of of fast rotating BSSs observed in M4. Thus, Omega Centauri is the second stellar cluster, beyond M4, with a surprisingly high population of fast spinning BSSs. We found a hint of a radial behaviour of the fraction of fast rotating BSSs, with a mild peak within one core radius, and a possibile rise in the external regions (beyond four core radii). This may suggest that recent formation episodes of mass transfer BSSs occurred preferentially in the outskirts of Omega Centauri, or that braking mechanisms able to slow down these stars are least efficient in lowest density environments.
description: Accepted for publication by ApJ. 30 pages, 11 figures, 1 table
title: Pulmonary paracoccidioidomycosis: an imaging dilemma.
Creators: name: Reina, Jhonathan
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Thorax
subject: Lung
subject: CT
subject: Conventional radiography
subject: Education
subject: Biopsy
subject: Infection
subject: Occupational / Environmental hazards

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe the most relevant radiologic manifestations of pulmonary paracoccidioidomycosis. To understand the clinical and epidemiologic features of paracoccidioidomycosis. To perform a proper differential diagnosis in order to establish the best...
title: Species Pairwise Associations Over Nine Years of Secondary Succession: Assessing Alternative Explanations and Successional Mechanisms
Creators: name: Rozzell, Lara R.
Publisher: name: Utah State University
Year: 2003

description: The importance and mechanisms of species interactions are undetermined in most successional systems. I used correlations and null modeling to detect pairwise species associations between 33 plant species in the first nine years of secondary succession after logging and burning in a western Oregon Cascade forest. I tested for correlations between each species and soil nutrients, nonvegetative ground cover, and surrounding vegetation. More positive than negative associations were found at all sampling times. The proportion of positive associations decreased and negative associations increased through time. Up to 42% of associations at a sampling time were explicable by shared positive correlations with surrounding vegetation. One domjnant shrub species, Berberis nervosa, may be primarily responsible for the decline of four early seral species. The associations indicated diffuse facilitation is of primary importance in the stressful early successional environment, and microsite availability and interspecific competition become more important later.
title: Computed Tomography (CT) in Gastric Urgencies: What radiologists need to know.
Creators: name: Quispe Mauricio, Angel
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Volvulus
subject: Trauma
subject: Haemorrhage
subject: eLearning
subject: Contrast agent-oral
subject: Contrast agent-intravenous
subject: PACS
subject: CT-Angiography
subject: CT
subject: Gastrointestinal tract
subject: Anatomy
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Review and illustrate the CT findings of urgent gastric pathology. Describe the key points for diagnostic imaging of gastric...
Additional file 2 of CD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice
Creators: name: Aguilera-Braico, Diego Maximo
name: Balogh, Gabriela A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology

description: Additional file 2: Table S2. CD19 PE labelled cell population in lymph node and spleen from BALBc mice
title: Μελέτη του ρόλου της οικογένειας αυξητικών παραγόντων του TGF-β στην εμβρυϊκή και μεταεμβρυϊκή ανάπτυξη και σε παθολογικές καταστάσεις φλεγμονής και ίνωσης
titleType: AlternativeTitle
Creators: name: Σταυρόπουλος, Αθανάσιος Α.
Publisher: name: University of Thessaly
Year: 2013
Subjects: subject: ΦΛΕΓΜΟΝΗ
subject: ΦΛΕΓΜΟΝΗ -- ΑΝΟΣΟΛΟΓΙΚΕΣ ΑΠΟΨΕΙΣ
subject: ΠΑΡΑΓΟΝΤΑΣ TGF-β

description: Σημείωση: διατίθεται συμπληρωματικό υλικό σε ξεχωριστό αρχείο.
title: Acute mesenteric ischemia: Causes, imaging findings and differential diagnosis.
Creators: name: Quispe Mauricio, Angel
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: Anatomy
subject: CT
subject: CT-Angiography
subject: PACS
subject: eLearning
subject: Contrast agent-other
subject: Education and training
subject: Mesentery
subject: Ischaemia / Infarction

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Describe and illustrate the imaging findings of acute mesenteric ischemia. To review the radiological findings of mesenteric ischemia according to the possible etiologies that cause...
Additional file 3 of CD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice
Creators: name: Aguilera-Braico, Diego Maximo
name: Balogh, Gabriela A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology

description: Additional file 3: Table S3. CD105 AF labelled cell population in lymph node and spleen from BALBc mice
Supplementary Material
Creators: name: Chen, Yicun
name: Huang, Ziqi
name: You, YongYong
name: jiang, Tianran
name: Wu, Huiping
name: Zheng, Zhaoqiang
name: Du, Chun
name: Chen, Ke
name: Lai, Tianshu
Publisher: name: AIP Publishing
Year: 2025
Subjects: classificationCode: 51
subject: Physical sciences
subject: FOS: Physical sciences

description: After the Conclusion and before the Acknowledgments of the manuscript, we have inserted a brief description of the Supplemental Material
title: Does hypertension affect the aging of white matter? - insights from DTI.
Creators: name: Sabisz, Agnieszka
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Hypertension
subject: Segmentation
subject: Computer Applications-Detection, diagnosis
subject: MR-Diffusion/Perfusion
subject: Neuroradiology brain

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: In the hypertensive patients’ population WM microstructure differences derived from DTI studies were reported in the corpus callosum. [Gons 2012, Maillard 2012] Additionally the SBP was linearly correlated with decreased regional FA and increased...
Magnetotransport in ferromagnetic Mn5Ge3, Mn5Ge3C0.8, and Mn5Si3C0.8 thin films
Creators: name: Sürgers, Christoph
name: Fischer, Gerda
name: Winkel, Patrick
name: Löhneysen, Hilbert v.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The electrical resistivity, anisotropic magnetoresistance (AMR), and anomalous Hall effect of ferromagnetic Mn5Ge3, Mn5Ge3C0.8, and Mn5Si3C0.8 thin films has been investigated. The data show a behavior characteristic for a ferromagnetic metal, with a linear increase of the anomalous Hall coefficient with Curie temperature. While for ferromagnetic Mn5Si3C0.8 the normal Hall coefficient R0 and the AMR ratio are independent of temperature, these parameters strongly increase with temperature for the germanide films. This difference is attributed to the different hybridization of electronic states in the materials due different lattice parameters and different atomic configurations (Ge vs. Si metalloid). The concomitant sign change of R0 and the AMR ratio with temperature observed for the germanide films is discussed in a two-current model indicating an electron-like minority-spin transport at low temperatures.
description: 7 figures
Additional file 4 of CD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice
Creators: name: Aguilera-Braico, Diego Maximo
name: Balogh, Gabriela A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology

description: Additional file 4: Table S4. L6G FITC labelled cell population in lymph node and spleen from BALBc mice.
Transcriptomic analysis of pathways associated with ITGAV/alpha(v) integrin-dependent autophagy in human B cells
Creators: name: Muir, Virginia
name: Sagadiev, Sara
name: Liu, Shuozhi
name: Holder, Ursula
name: Armendariz, Andrea M.
name: Suchland, Emmaline
name: Meitlis, Iana
name: Camp, Nathan
name: Giltiay, Natalia
name: Tam, Jenny M.
name: Garner, Ethan C.
name: Wivagg, Carl N.
name: Shows, Donna
name: James, Richard G.
name: Lacy-Hulbert, Adam
name: Acharya, Mridu
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Macroautophagy/autophagy proteins have been linked with the development of immune-mediated diseases including lupus, but the mechanisms for this are unclear due to the complex roles of these proteins in multiple immune cell types. We have previously shown that a form of noncanonical autophagy induced by ITGAV/alpha(v) integrins regulates B cell activation by viral and self-antigens, in mice. Here, we investigate the involvement of this pathway in B cells from human tissues. Our data reveal that autophagy is specifically induced in the germinal center and memory B cell subpopulations of human tonsils and spleens. Transcriptomic analysis show that the induction of autophagy is related to unique aspects of activated B cells such as mitochondrial metabolism. To understand the function of ITGAV/alpha(v) integrin-dependent autophagy in human B cells, we used CRISPR-mediated knockdown of autophagy genes. Integrating data from primary B cells and knockout cells, we found that ITGAV/alpha(v)-dependent autophagy limits activation of specific pathways related to B cell responses, while promoting others. These data provide new mechanistic links for autophagy and B-cell-mediated immune dysregulation in diseases such as lupus.
Mid-Infrared Spectroscopy of Uranus from the Spitzer Infrared Spectrometer: 2. Determination of the Mean Composition of the Upper Troposphere and Stratosphere
Creators: name: Orton, Glenn S.
name: Moses, J. I.
name: Fletcher, Leigh N.
name: Mainzer, Amy K.
name: Hines, Dean
name: Hammel, Heidi B.
name: Martin-Torres, Javier
name: Burgdorf, Martin
name: Merlet, Cecile
name: Line, Michael R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Mid-infrared spectral observations Uranus acquired with the Infrared Spectrometer (IRS) on the Spitzer Space Telescope are used to determine the abundances of C2H2, C2H6, CH3C2H, C4H2, CO2, and tentatively CH3 on Uranus at the time of the 2007 equinox. For vertically uniform eddy diffusion coefficients in the range 2200-2600 cm2 s-1, photochemical models that reproduce the observed methane emission also predict C2H6 profiles that compare well with emission in the 11.6-12.5 micron wavelength region, where the nu9 band of C2H6 is prominent. Our nominal model with a uniform eddy diffusion coefficient Kzz = 2430 cm2 sec-1 and a CH4 tropopause mole fraction of 1.6x10-5 provides a good fit to other hydrocarbon emission features, such as those of C2H2 and C4H2, but the model profile for CH3C2H must be scaled by a factor of 0.43, suggesting that improvements are needed in the chemical reaction mechanism for C3Hx species. The nominal model is consistent with a CH3D/CH4 ratio of 3.0+-0.2x10-4. From the best-fit scaling of these photochemical-model profiles, we derive column abundances above the 10-mbar level of 4.5+01.1/-0.8 x 10+19 molecule-cm-2 for CH4, 6.2 +- 1.0 x 10+16 molecule-cm-2 for C2H2 (with a value 24% higher from a different longitudinal sampling), 3.1 +- 0.3 x 10+16 molecule-cm-2 for C2H6, 8.6 +- 2.6 x 10+13 molecule-cm-2 for CH3C2H, 1.8 +- 0.3 x 10+13 molecule-cm-2 for C4H2, and 1.7 +- 0.4 x 10+13 molecule-cm-2 for CO2 on Uranus. Our results have implications with respect to the influx rate of exogenic oxygen species and the production rate of stratospheric hazes on Uranus, as well as the C4H2 vapor pressure over C4H2 ice at low temperatures.
title: Acute Scrotum Syndrome: Anatomy, differential diagnosis and radiological findings.
Creators: name: Quispe Mauricio, Angel
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Anatomy
subject: Pelvis
subject: Genital / Reproductive system male
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Ultrasound-Power Doppler
subject: Biopsy
subject: Complications
subject: eLearning
subject: Abscess
subject: Acute
subject: Trauma

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Describe and illustrate the findings by image of acute scrotal...
The Next Generation Virgo Cluster Survey. XV. The photometric redshift estimation for background sources
Creators: name: Raichoor, A.
name: Mei, S.
name: Erben, T.
name: Hildebrandt, H.
name: Huertas-Company, M.
name: Ilbert, O.
name: Licitra, R.
name: Ball, N. M.
name: Boissier, S.
name: Boselli, A.
name: Chen, Y. -T.
name: Côté, P.
name: Cuillandre, J. -C.
name: Duc, P. A.
name: Durrell, P. R.
name: Ferrarese, L.
name: Guhathakurta, P.
name: Gwyn, S. D. J.
name: Kavelaars, J. J.
name: Lançon, A.
name: Liu, C.
name: MacArthur, L. A.
name: Muller, M.
name: Muñoz, R. P.
name: Peng, E. W.
name: Puzia, T. H.
name: Sawicki, M.
name: Toloba, E.
name: Van Waerbeke, L.
name: Woods, D.
name: Zhang, H.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The Next Generation Virgo Cluster Survey is an optical imaging survey covering 104 deg^2 centered on the Virgo cluster. Currently, the complete survey area has been observed in the u*giz-bands and one third in the r-band. We present the photometric redshift estimation for the NGVS background sources. After a dedicated data reduction, we perform accurate photometry, with special attention to precise color measurements through point spread function-homogenization. We then estimate the photometric redshifts with the Le Phare and BPZ codes. We add a new prior which extends to iAB = 12.5 mag. When using the u*griz-bands, our photometric redshifts for 15.5 \le i \lesssim 23 mag or zphot \lesssim 1 galaxies have a bias |Δz| < 0.02, less than 5% outliers, and a scatter σ_{outl.rej.} and an individual error on zphot that increase with magnitude (from 0.02 to 0.05 and from 0.03 to 0.10, respectively). When using the u*giz-bands over the same magnitude and redshift range, the lack of the r-band increases the uncertainties in the 0.3 \lesssim zphot \lesssim 0.8 range (-0.05 < Δz < -0.02, σ_{outl.rej} ~ 0.06, 10-15% outliers, and zphot.err. ~ 0.15). We also present a joint analysis of the photometric redshift accuracy as a function of redshift and magnitude. We assess the quality of our photometric redshifts by comparison to spectroscopic samples and by verifying that the angular auto- and cross-correlation function w(θ) of the entire NGVS photometric redshift sample across redshift bins is in agreement with the expectations.
description: Accepted for publication in ApJS. 24 pages, 21 Figures (some with degraded quality to fit the arxiv size limit), 6 Tables
Ambra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration
Creators: name: Ramírez-Pardo, Ignacio
name: Villarejo-Zori, Beatriz
name: Jiménez-Loygorri, Juan Ignacio
name: Sierra-Filardi, Elena
name: Alonso-Gil, Sandra
name: Mariño, Guillermo
name: de la Villa, Pedro
name: Fitze, Patrick S
name: Fuentes, José Manuel
name: García-Escudero, Ramón
name: Ferrington, Deborah A.
name: Gomez-Sintes, Raquel
name: Boya, Patricia
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Macroautophagy/autophagy is a key process in the maintenance of cellular homeostasis. The age-dependent decline in retinal autophagy has been associated with photoreceptor degeneration. Retinal dysfunction can also result from damage to the retinal pigment epithelium (RPE), as the RPE-retina constitutes an important metabolic ecosystem that must be finely tuned to preserve visual function. While studies of mice lacking essential autophagy genes have revealed a predisposition to retinal degeneration, the consequences of a moderate reduction in autophagy, similar to that which occurs during physiological aging, remain unclear. Here, we described a retinal phenotype consistent with accelerated aging in mice carrying a haploinsufficiency for Ambra1, a pro-autophagic gene. These mice showed protein aggregation in the retina and RPE, metabolic underperformance, and premature vision loss. Moreover, Ambra1+/gt mice were more prone to retinal degeneration after RPE stress. These findings indicate that autophagy provides crucial support to RPE-retinal metabolism and protects the retina against stress and physiological aging. Abbreviations : 4-HNE: 4-hydroxynonenal; AMBRA1: autophagy and beclin 1 regulator 1, AMD: age-related macular degeneration;; GCL: ganglion cell layer; GFAP: glial fibrillary acidic protein; GLUL: glutamine synthetase/glutamate-ammonia ligase; HCL: hierarchical clustering; INL: inner nuclear layer; IPL: inner plexiform layer; LC/GC-MS: liquid chromatography/gas chromatography–mass spectrometry; MA: middle-aged; MTDR: MitoTracker Deep Red; MFI: mean fluorescence intensity; NL: NH4Cl and leupeptin; Nqo: NAD(P)H quinone dehydrogenase; ONL: outer nuclear layer; OPL: outer plexiform layer; OP: oscillatory potentials; OXPHOS: oxidative phosphorylation; PCR: polymerase chain reaction; PRKC/PKCα: protein kinase C; POS: photoreceptor outer segment; RGC: retinal ganglion cells; RPE: retinal pigment epithelium; SI: sodium iodate; TCA: tricarboxylic acid.
Nonlinear transmission spectroscopy with dual frequency combs
Creators: name: Glenn, Rachel
name: Mukamel, Shaul
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We show how two frequency combs $\mathcal{E}_1$, $\mathcal{E}_2$ can be used to measure single-photon, two-photon absorption (TPA), and Raman resonances in a molecule with three electronic bands, by detecting the radio frequency modulation of the nonlinear transmission signal. Some peaks are independent of the carrier frequency of the comb and others shift with that frequency and have a width close to the comb width. TPA and Raman resonances independent of the carrier frequency are selected by measuring the transmission signal $\sim\mathcal{E}_1^2 \mathcal{E}_2^2$ and the single-photon resonances are selected by measuring the transmission signal $\sim\mathcal{E}_1^3\mathcal{E}_2$. Sinusoidal spectral phase shaping strongly affects the TPA, but not the Raman resonances.
description: 13 pages, 11 Figures
title: Diagnostic efficacy of FDG PET CT in the evaluation of patients with pyrexia of unknown origin (PUO) in the Indian population
Creators: name: Logudas, Muralikrishna
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Hybrid Imaging
subject: Molecular imaging
subject: Nuclear medicine
subject: PET-CT
subject: Efficacy studies
subject: Molecular imaging
subject: Cost-effectiveness
subject: Infection
subject: Inflammation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Pyrexia of Unknown Orgin (PUO) is defined as fever of 3 weeks duration with body temperature above 38.5 o C on several occasions and no established diagnosis after one week of hospitalisation or two weeks of outpatient investigation. In a densely...
The last of the simple remainders
Creators: name: Brandhuber, Andreas
name: Penante, Brenda
name: Travaglini, Gabriele
name: Wen, Congkao
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute the n-point two-loop form factors of the half-BPS operators Tr(phi_{AB}^n) in N=4 super Yang-Mills for arbitrary n >2 using generalised unitarity and symbols. These form factors are minimal in the sense that the n^{th} power of the scalar field in the operator requires the presence of at least n on-shell legs. Infrared divergences are shown to exponentiate as for amplitudes, reproducing the known cusp and collinear anomalous dimensions at two loops. We define appropriate infrared-finite remainder functions and compute them analytically for all n. The results obtained by using the known expressions of the integral functions involve complicated combinations of Goncharov multiple polylogarithms, but we show that much simpler expressions can in fact be derived using the symbol of transcendental functions. For n=3 we find a very compact remainder function expressed in terms of classical polylogarithms only. For arbitrary n>3 we are able to write all the remainder functions in terms of a single compact building block, expressed as a sum of classical polylogarithms augmented by two multiple polylogarithms. The decomposition of the symbol into specific components is crucial in order to single out a natural combination of multiple polylogarithms. Finally, we analyse in detail the behaviour of these minimal form factors in collinear and soft limits, which deviates from the usual behaviour of amplitudes and non-minimal form factors.
description: 31 pages, LaTeX
BECN1F121A mutation increases autophagic flux in aged mice and improves aging phenotypes in an organ-dependent manner
Creators: name: Sebti, Salwa
name: Zou, Zhongju
name: Shiloh, Michael U.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Macroautophagy/autophagy is necessary for lifespan extension in multiple model organisms and autophagy dysfunction impacts age-related phenotypes and diseases. Introduction of an F121A mutation into the essential autophagy protein BECN1 constitutively increases basal autophagy in young mice and reduces cardiac and renal age-related changes in longer lived Becn1F121A mutant mice. However, both autophagic and lysosomal activities decline with age. Thus, whether autophagic flux is maintained during aging and whether it is enhanced in Becn1F121A mice is unknown. Here, we demonstrate that old wild-type mice maintained functional autophagic flux in heart, kidney and skeletal muscle but not liver, and old Becn1F121A mice had increased autophagic flux in those same organs compared to wild type. In parallel, Becn1F121A mice were not protected against age-associated hepatic phenotypes but demonstrated reduced skeletal muscle fiber atrophy. These findings identify an organ-specific role for the ability of autophagy to impact organ aging phenotypes.
title: Adrenal hemorrhage - a review of causes and CT characteristics
Creators: name: Sekulic, Danijela
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Haemorrhage
subject: Epidemiology
subject: Acute
subject: Education
subject: Diagnostic procedure
subject: CT
subject: Retroperitoneum

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To illustrate different imaging characteristics of hemorrhage in adrenal glands. To analyze various clinical settings, including both traumatic and non-traumatic conditions, in which adrenal hemorrhage...
Additional file 1 of Metagenomics-resolved genomics provides novel insights into chitin turnover, metabolic specialization, and niche partitioning in the octocoral microbiome
Creators: name: Keller-Costa, Tina
name: Kozma, Lydia
name: Silva, Sandra G.
name: Toscan, Rodolfo
name: Gonçalves, Jorge
name: Lago-Lestón, Asunción
name: Kyrpides, Nikos C.
name: Nunes da Rocha, Ulisses
name: Costa, Rodrigo
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1: Figure S1. Phylogenomic analysis of the Ca. Thioglobaceae family using SpeciesTreeBuilder v.01.0. Figure S2. COG functions (N=76) significantly enriched (q-value < 0.05) in the octocoral-derived Ca. Gorgonimonas (Endozoicomonadaceae) MAGs (N= 11, green), compared with all other MAGs (N=55) of this dataset. Figure S3. KEGG metabolic pathway map of the Ca. Gorgonimonas (Endozoicomonadaceae) MAGs of this study. Figure S4. Phylogeny of 101 full-length, bacterial endo-chitinase (EC 3.2.1.14) encoding genes, including the 11 endo-chitinase (GH18-family) genes from Endozoicomonadaceae MAGs (grey shadings) of this study. Figure S5. COG functions (N=34) significantly enriched (p-value < 0.05) in the Ca. Thioglobaceae MAGs (N= 6, dark green), compared with all other MAGs (N=60) of this dataset. An one-sided Welch’s t-test for unequal variances was performed in STAMP v.2.1.3. Multiple test correction was performed using the Benjamini-Hochberg correction (FDR). To further limit the displayed number of significant entries, an effect size filter was also applied, setting the “ratio of proportions” to 5.00. Figure S6. KEGG metabolic pathway map of the Ca. Thioglobaceae MAGs of this study. The metabolic map features glycolysis, pyruvate, nitrogen, sulfur, and taurine metabolism. EC numbers of enzymes catalyzing the reactions are given in rectangular boxes. EC numbers highlighted in green represent enzymes encoded on Ca. Thioglobaceae MAGs. Beige boxes indicate connections to other metabolic pathways active in these MAGs. Figure S7. KEGG carbon fixation map of Ca. Thiocorallibacter gorgonii MAG EG15H_Bin1 (Ca. Thioglobaceae). EC numbers of enzymes catalyzing the reactions are given in rectangular boxes. EC numbers highlighted in green represent enzymes encoded on this MAG. Beige boxes indicate connections to other metabolic pathways active in these MAGs. Orange dots highlight the substrates (Ribulose-1,5-bisphosphate, CO2, and H2O) and product (2 Glycerate-3-phosphate, 2 H+) of Rubisco (EC 4.1.1.39).
title: Percutaneus endoluminal forceps biopsy in cholangiocelular carcinoma: cost effectiveness analysis
Creators: name: Rohan, Tomas
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Interventional non-vascular
subject: Biliary Tract / Gallbladder
subject: Oncology
subject: Fluoroscopy
subject: Biopsy
subject: Cost-effectiveness

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Endoluminal forceps biopsy is a preferred methodof obtaining specimens for histopathological analysis of suspected malignant biliary obstruction. However, the optimal timing for endoluminal forceps biopsy is not yet clear. It can be performed...
Mid-Infrared Spectroscopy of Uranus from the Spitzer Infrared Spectrometer: 1. Determination of the Mean Temperature Structure of the Upper Troposphere and Stratosphere
Creators: name: Orton, Glenn S.
name: Fletcher, Leigh N.
name: Moses, Julianne I.
name: Mainzer, Amy K.
name: Hines, Dean
name: Hammel, Heidi B.
name: Martin-Torres, F. Javier
name: Burgdorf, Martin
name: Merlet, Cecile
name: Line, Michael R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: On 2007 December 16-17, spectra were acquired of the disk of Uranus by the Spitzer Infrared Spectrometer (IRS) when its equator was close to the sub-earth point. This spectrum provides the highest-resolution broad-band spectrum ever obtained for Uranus from space, allowing a determination of the disk-averaged temperature and molecule composition to a greater degree of accuracy than ever before. The temperature profiles derived from the Voyager radio occultation experiments that match these data best are those that assume a high abundance of methane in the deep atmosphere, but none of these models provides a satisfactory fit over the full spectral range. This be the result of spatial differences between global and low-latitudinal regions, changes in time, missing continuum opacity sources such as stratospheric hazes or unknown tropospheric constituents, or undiagnosed systematic problems with either the radio-occultation or the Spitzer IRS data sets. The spectrum is compatible with the stratospheric temperatures derived from the Voyager ultraviolet occultations measurements. Thermospheric temperatures determined from the analysis of the observed H2 quadrupole emission features are colder than those derived by Herbert et al. at pressures less than ~1 microbar. Extrapolation of the nominal model spectrum to far-infrared through millimeter wavelengths shows that the spectrum arising solely from H2 collision-induced absorption is too warm to reproduce observations between wavelengths of 0.8 and 3.3 mm. Adding an additional absorber such as H2S provides a reasonable match to the spectrum, although a unique identification of the responsible absorber is not yet possible with available data. An immediate practical use for the spectrum resulting from this model is to establish a high-precision continuum flux model for use as an absolute radiometric standard for future astronomical observations.
Twist-controlled resonant tunnelling in graphene-boron nitride-graphene heterostructures
Creators: name: Mishchenko, A.
name: Tu, J. S.
name: Cao, Y.
name: Gorbachev, R. V.
name: Wallbank, J. R.
name: Greenaway, M. T.
name: Morozov, V. E.
name: Morozov, S. V.
name: Zhu, M. J.
name: Wong, S. L.
name: Withers, F.
name: Woods, C. R.
name: Kim, Y. -J.
name: Watanabe, K.
name: Taniguchi, T.
name: Vdovin, E. E.
name: Makarovsky, O.
name: Fromhold, T. M.
name: Falko, V. I.
name: Geim, A. K.
name: Eaves, L.
name: Novoselov, K. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Recent developments in the technology of van der Waals heterostructures made from two-dimensional atomic crystals have already led to the observation of new physical phenomena, such as the metal-insulator transition and Coulomb drag, and to the realisation of functional devices, such as tunnel diodes, tunnel transistors and photovoltaic sensors. An unprecedented degree of control of the electronic properties is available not only by means of the selection of materials in the stack but also through the additional fine-tuning achievable by adjusting the built-in strain and relative orientation of the component layers. Here we demonstrate how careful alignment of the crystallographic orientation of two graphene electrodes, separated by a layer of hexagonal boron nitride (hBN) in a transistor device, can achieve resonant tunnelling with conservation of electron energy, momentum and, potentially, chirality. We show how the resonance peak and negative differential conductance in the device characteristics induces a tuneable radio-frequency oscillatory current which has potential for future high frequency technology.
description: For Supplementary Information see http://www.nature.com/nnano/journal/vaop/ncurrent/extref/nnano.2014.187-s1.pdf
title: Multiparametric breast magnetic resonance imaging (MRI) in the prediction of tumour-infiltrating lymphocytes (TILs) in breast cancer
Creators: name: Venturini, Elena
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Breast
subject: MR
subject: Diagnostic procedure

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Tumor-infiltrating lymphocytes (TILs) reflect the attempt of the immune system to recognize and eradicate malignancies and own an interesting prognostic value in breast cancer, especially in triple negative (TN) and HER2+ subtypes. Immune...
Feasible Point Pursuit and Successive Approximation of Non-convex QCQPs
Creators: name: Mehanna, Omar
name: Huang, Kejun
name: Gopalakrishnan, Balasubramanian
name: Konar, Aritra
name: Sidiropoulos, Nicholas D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: Quadratically constrained quadratic programs (QCQPs) have a wide range of applications in signal processing and wireless communications. Non-convex QCQPs are NP-hard in general. Existing approaches relax the non-convexity using semi-definite relaxation (SDR) or linearize the non-convex part and solve the resulting convex problem. However, these techniques are seldom successful in even obtaining a feasible solution when the QCQP matrices are indefinite. In this paper, a new feasible point pursuit successive convex approximation (FPP-SCA) algorithm is proposed for non-convex QCQPs. FPP-SCA linearizes the non-convex parts of the problem as conventional SCA does, but adds slack variables to sustain feasibility, and a penalty to ensure slacks are sparingly used. When FPP-SCA is successful in identifying a feasible point of the non-convex QCQP, convergence to a Karush-Kuhn-Tucker (KKT) point is thereafter ensured. Simulations show the effectiveness of our proposed algorithm in obtaining feasible and near-optimal solutions, significantly outperforming existing approaches.
description: Submitted to the IEEE Signal Processing Letters
title: Neoplastic Diseases of the Meninges- A Pictorial Review
Creators: name: Chattopadhyay, Arpita
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Neoplasia
subject: Cancer
subject: Radiation therapy / Oncology
subject: MR
subject: CT
subject: Neuroradiology brain
subject: CNS

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - To provide a comprehensive review of both primary and secondary neoplastic processes that involve the meninges. - To illustrate a wide spectrum of neoplastic lesions and review the role of imaging in their diagnosis and...
Additional file 1 of How to deal with moral challenges around the decision-making competence in transgender adolescent care? Development of an ethics support tool
Creators: name: de Snoo-Trimp, Janine
name: de Vries, Annelou
name: Molewijk, Bert
name: Hein, Irma
Publisher: name: figshare
Year: 2022
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Interview guide and overview of decision-moments.
title: MRI Utiliy in Lupus Myocarditis: Easy pictorial review.
Creators: name: Dautt Medina, Paulette
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cardiac
subject: MR-Functional imaging
subject: MR
subject: Imaging sequences
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - To the radiologist knows the main cardiac affections of SLE with focus on myocarditis. -To know the image method of choice for myocarditis. - To know the basic sequences for diagnosis and...
OMC/INTEGRAL photometric observations of pulsating components in eclipsing binaries and characterization of DY Aqr
Creators: name: Alfonso-Garzon, Julia
name: Montesinos, Benjamin
name: Moya, Andres
name: Mas-Hesse, J. Miguel
name: Martin-Ruiz, Susana
Publisher: name: arXiv
Year: 2014
Subjects: subject: Space Physics (physics.space-ph)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present the search for eclipsing binaries with a pulsating component in the first catalogue of optically variable sources observed by OMC/INTEGRAL, which contains photometric data for more than 1000 eclipsing binaries. Five objects were found and a detailed analysis of one of them, DY Aqr, has been performed. Photometric and spectroscopic observations of DY Aqr were obtained to analyse the binary system and the pulsational characteristics of the primary component. By applying the binary modelling software phoebe to the OMC and ground-based photometric light curves, and to the radial velocity curve obtained using echelle high-resolution spectroscopy, the physical parameters of the system have been determined. Frequency analysis of the residual data has been performed using Fourier techniques to identify pulsational frequencies. We have built a grid of theoretical models to classify spectroscopically the primary component as an A7.5V star (plus or minus one spectral subtype). The best orbital fit was obtained for a semi-detached system configuration. According to the binary modelling, the primary component has Teff = 7625+-125 K and log g = 4.1+-0.1 and the secondary component has Teff = 3800+-200 K and log g = 3.3+-0.1, although it is too faint to isolate its spectral features. From the analysis of the residuals we have found a main pulsation frequency at 23.37 c/d, which is typical of a delta Scuti star. In the O-C diagram no evidence of orbital period changes over the last 8 years has been found.
description: 12 pages, 10 figures. Accepted for publication in MNRAS
Additional file 2 of How to deal with moral challenges around the decision-making competence in transgender adolescent care? Development of an ethics support tool
Creators: name: de Snoo-Trimp, Janine
name: de Vries, Annelou
name: Molewijk, Bert
name: Hein, Irma
Publisher: name: figshare
Year: 2022
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Screenshots of the first pages of the Ethics Support Tool, ‘deWilsbekwaamheidswijzer’.