cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: An investigation into the contribution that women are making to communities through their involvement in small Voluntary and Community Sector Organisations (VCSOs) operating in the South West Region
Creators: name: Crawley, J.E
Publisher: name: Bath Spa University
Year: 2016

description: This research investigated the contribution that women are making to communities through their involvement in small Voluntary and community sector organisations (VCSOs) operating in the South West Region of England. The research explored the roles the women play and what type of involvement they have in the development and delivery of services through small VCSOs. It also considered what motivates the women to become involved and to stay involved in these small groups and how visible and valued that involvement is. The research utilised a feminist approach with mixed methods to provide a space for the voices of the women involved to be heard and over 200 women from small ‘Below the Radar’ (BTR) VCSOs took part including over 180 by completing scoping questionnaires, thirty-two in two focus groups and twelve who took part in semi-structured interviews. The study found the context and circumstances in which small VCSOs operate contained factors, which have either encouraged or discouraged the involvement of women in their communities, including issues related to women’s current position in society. The commitment, passion and desire to carry out work, which would benefit the whole community, were among the key reasons the women undertook the work, rather than financial reward or status. The work of the women involved in the research was also found to contribute to stocks of social capital in those communities. The research analysed the degree to which recent governments have sought to utilise the VCS to assist with the delivery of their own agendas. The research suggests that women’s involvement within the smaller BTR VCSOs could be conceptualised in a framework called the ‘Women Alchemists’ and that the use of the term ‘Women Led Organisations’ could more fully build on the contribution of women and to nurture it in a way which enables it to grow and be sustained without altering its nature.
title: Queen Bea: a novel [and] No me without you: how concepts of self as mutable and multiple shaped the YA novel Queen Bea
Creators: name: Nadin, J
Publisher: name: Bath Spa University
Year: 2016

description: This dissertation comprises a young adult novel and contextualising thesis. The novel Queen Bea explores concepts of multiple self and narcissism as normative states for adolescents. The contextualising thesis is an intensely personal piece. It charts not only the transformation of the novel following research into the concept of mutable and multiple self, but also the author’s own metamorphoses from childhood, through adulthood, into her own acceptance of multiple selves, and the implications for her writing. It comprises an introduction, four chapters and a conclusion. The introduction sets out the scope, methodology and limitations, as well as offering an insight into Nadin’s interest in ‘self’. In the opening chapter she discusses the background to Queen Bea, including the teenage transformations that have characterised her work, contextualising the work within the YA tradition of ‘quest for self’ novels. In Chapter 2 she looks at the influence the concepts of a ‘mutable and multiple’ self and ‘necessary narcissism’ had on her thinking and on the structure and content of the novel, in particular referencing Julian Baggini, Bruce Hood, Erik Erikson and Elizabeth Lunbeck. Chapter 3 attempts to situate her work within the context of other YA literature that has explored mutable or multiple self, including David Levithan’s novel Every Day. Chapter 4 looks in greater detail at some of the ways in which she has tried to weave her thoughts on self and self-obsession into plot, form and characterisation in the final draft of Queen Bea. She concludes by discussing whether or not she believes Queen Bea achieves what she set out to achieve, and what the implications are going forward. This is followed by appendices and a bibliography.
Kinematic Cusps with Two Missing Particles II: Cascade Decay Topology
Creators: name: Han, Tao
name: Kim, Ian-Woo
name: Song, Jeonghyeon
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Three-step cascade decays into two invisible particles and two visible particles via two intermediate on-shell particles develop cusped peak structures in several kinematic distributions. We study the basic properties of the cusps and endpoints in various distributions and demonstrate that the masses of the missing particles and the intermediate particles can be determined by the cusp and endpoint positions. Effects from realistic considerations such as finite decay widths, longitudinal boost of the parent particle, and spin correlations are shown to be under control for the processes illustrated.
description: references added, 31 pages with 21 figures and 3 tables
Bound state nature of the exotic Z_b states
Creators: name: Cleven, Martin
name: Guo, Feng-Kun
name: Hanhart, Christoph
name: Meißner, Ulf-G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The assumption that the newly observed charged bottomonia states Z_b(10610) and Z_b(10650) are of molecular nature is confronted with the measured invariant mass distributions for the transitions of the Upsilon(5S) to the final states h_b pi^+ pi^- and h_b(2P) pi^+ pi^-. It is shown that the assumption that the Z_b(10610) and Z_b(10650) are B\bar B^*+{\rm c.c.} and B^*\bar B^* bound states, respectively, with very small binding energies is consistent with the data. The calculation is based on a power counting for bottom meson loops, which is explicitly given up to two-loop in the framework of a nonrelativistic effective field theory. We also show that if the Z_b states are of molecular nature, then the data should not be analyzed by using a Breit-Wigner parametrization.
description: 8 pages, 5 figures. Typos corrected, version appeared in Eur. Phys. J. A
Binding selectivity-dependent molecular mechanism of inhibitors towards CDK2 and CDK6 investigated by multiple short molecular dynamics and free energy landscapes
Creators: name: Wang, Lifei
name: Lu, Dan
name: Wang, Yan
name: Xu, Xiaoyan
name: Zhong, Peihua
name: Yang, Zhiyong
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Understanding selectivity-dependent molecular mechanism of inhibitors towards CDK2 over CDK6 is prominent for improving drug design towards the CDK family. Multiple short molecular dynamics (MD) simulations combined with MM-GBSA approach are adopted to investigate molecular mechanism on binding selectivity of inhibitors X64, X3A, and 4 AU to CDK2 and CDK6. The RMSF analysis and calculations of molecular surface areas indicate that local structural and global flexibility of CDK6 are stronger than that of CDK2. Based on dynamics cross-correlation maps (DCCMs), motion modes of CDK2 and CDK6 produce difference due to associations of X64, X3A, and 4 AU. The calculated binding free energies (BFEs) demonstrate that the compensation between binding enthalpy and entropy of X64, X34, and 4 AU is a key force driving selectivity of inhibitors towards CDK2 over CDK6. This work provides valuable information for designing highly selective inhibitors towards CDK2 and CDK6 and further promotes identification of efficient anticancer drugs in the future.
Optimal path planning using spatial neighborhood properties
Creators: name: Bhattacharya, Priyadarshi
Publisher: name: University of Calgary
Year: 2007

description: Bibliography: p. 184-195
description: Some pages are in colour.
description: The path planning problem, in its most well-know form, is the determination of a collision­free path for a mobile agent between source and destination. For practical path planning applications, a path should be as short as possible while maintaining a certain amount of clearance from obstacles. The problem is challenging as very few existing algorithms can fully satisfy both conditions. Very recently, improving path quality has received increased attention from researchers in the areas of GIS and robotics. In the first part of the thesis, we present a novel approach of combining path length with clearance from obstacles to generate an optimal path in just O(nlogn) time. In the second part, we provide a novel algorithm to solve the weighted region problem (wrp), concerned with determining an optimal path in a weighted terrain. Our algorithm is asymptotically faster than other existing approaches to solve the wrp and generates high quality optimal paths. We also provide a full description of the developed software system and extensive experimentation performed on GIS data.
The physics potential of proton-nucleus collisions at the TeV scale
Creators: name: Salgado, Carlos A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The LHC brings nuclear collisions to the TeV scale for the first time and the first data show the qualitative differences of this new regime. The corresponding phase-space available encompasses completely uncharted regions of QCD in which high-density or high-temperature domains can be identified. Proton-nucleus runs are essential for a complete interpretation of the data and for the study of new regimes dominated by large occupation numbers in the hadronic wave function. I comment here the physics opportunities for p+Pb runs at the LHC and d+Au runs at RHIC and the corresponding needs in view of the new Pb+Pb data from the LHC.
description: Proceedings of the conference Quark Matter 2011, Annecy (France) May 2011
Aspects of Quantum Gravity in Cosmology
Creators: name: Rinaldi, Massimiliano
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We review some aspects of quantum gravity in the context of cosmology. In particular, we focus on models with a phenomenology accessible to current and near-future observations, as the early Universe might be our only chance to peep through the quantum gravity realm.
description: 15 pages, 1 figure. Invited review for Modern Physics Letter A. Version 2: minor typos corrected, few references added
On the Packing Dimension and Category of Exceptional Sets of Orthogonal Projections
Creators: name: Orponen, Tuomas
Publisher: name: arXiv
Year: 2012
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: We consider several classical results related to the Hausdorff dimension of exceptional sets of orthogonal projections and try to find out whether they have reasonable formulations in terms of packing dimension. We also investigate the existence of category versions for Marstrand and Falconer-Howroyd-type projection results.
description: 42 pages, 5 figures. v3: improved Theorem 1.9
Supplementary document for Image Reconstruction Algorithms and their Selection Criteria for Terahertz Applications - 5830215.pdf
Creators: name: Barket, Ali Raza
name: Hu, Weidong
name: Wang, Bing
name: Shehzad, Waseem
name: Malik, Jabir Shabbir
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Optical Technology

description: Abbreviations used in the paper
Alternative methodologies for the quality control of LiDAR systems
Creators: name: Al-Durgham, Mohannad M.
Publisher: name: University of Calgary
Year: 2007

description: Bibliography: p. 91-94
description: Some pages are in colour.
description: The ever improving capabilities of GNSS/INS direct geo-referencing technology is having a positive impact on the widespread adoption of LiDAR systems for the acquisition of dense and accurate surface models over extended areas. Unlike with photogrammetric techniques, derived footprints from a LiDAR system are not based on redundant measurements, which are manipulated in an adjustment procedure. Consequently, there are no associated measures (e.g., variance component of unit weight and variance-covariance matrices of the derived parameters) that can be used to evaluate the quality of the final product. In this regard, a LiDAR system is usually viewed as a black box that lacks a well defined set of quality control procedures. This research introduces alternative procedures for evaluating the internal quality of LiDAR data. However, these procedures could be used for external quality control as well. The main premise of the proposed methodologies is that overlapping LiDAR strips will represent the same surface if and only if there are no biases in the derived surfaces. Therefore, the quality of coincidence between overlapping strips will be used as the basis for deriving the quality control measures.
Homola coriolisi Guinot & Richer de Forges 1995
Creators: name: Forges, Bertrand Richer De
name: Ng, Peter K. L.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Homolidae
Homola
Homola coriolisi

description: Homola coriolisi Guinot & Richer de Forges, 1995 (Figs. 1B, D, 15A) Homola coriolisi Guinot & Richer de Forges, 1995: 342, figs. 9f, 11e–f, 12D, 13d. – Cleva et al. 2007: 249, fig. 17B. – Richer de Forges & Ng 2007: 32. – Ng et al. 2008: 40. Material examined. Vanuatu: Espiritu Santo I., SANTO 2006, stn. AT 10, 15°41.1’S 167°00.5’E, 509–659 m, 17 September 2006: 1 male (12.8 x 11.2 mm) (MNHN-B31278).— Stn. AT 72, 15°44.1’S 167°03.3’E, 618–722 m, 7 October 2006: 1 female (15.1 x 12.9 mm, photographed) (ZRC 2008.0976). Remarks. Homola coriolisi, originally described from New Caledonia (Guinot & Richer de Forges 1995), is here recorded for the first time from Vanuatu. It is a relatively small-size species close to H. ikedai Sakai, 1979, but differs mainly in having a proportionately wider carapace than H. ikedai and the orientation of the anterolateral spines being less divergent and more gently curved in H. coriolisi. From the available data, H. coriolisi also apparently lives at somewhat greater depths (exceeding 400 m and up to 722 m) than H. ikedai (200–650 m) (see Richer de Forges & Ng 2007). The carapace of live specimens is marbled yellow with red patches, the ambulatory legs are banded red and yellow, and the chelae are white, contrasting with the yellowish-brown of the rest of the body (Fig. 15A).
description: Published as part of Forges, Bertrand Richer De & Ng, Peter K. L., 2008, New western Pacific records of Homolidae De Haan, 1839, with descriptions of new species of Homolochunia Doflein, 1904, and Latreillopsis Henderson, 1888 (Crustacea: Decapoda: Brachyura), pp. 1-35 in Zootaxa 1967 on pages 2-5
description: {"references": ["Guinot, D. & Richer de Forges, B. (1995) Crustacea Decapoda Brachyura: Revision de la famille des Homolidae de Haan, 1839. In: A. Crosnier (ed.), Resultats des campagnes MUSORSTOM, Volume 13. Memoires du Museum national d'Histoire naturelle, 163, 283 - 517.", "Cleva, R., Guinot, D. & Albenga, L. (2007) Annotated catalogue of brachyuran type specimens (Crustacea, Decapoda, Brachyura) deposited in the Museum national d'Histoire naturelle, Paris. Part I. Podotremata. Zoosystema, 29 (2), 229 - 279.", "Richer de Forges, B. & Ng, P. K. L. (2007) New records and new species of Homolidae de Haan, 1839, from the Philippines and French Polynesia (Crustacea: Decapoda: Brachyura). Raffles Bulletin of Zoology, Supplement 16, 29 - 45.", "Ng, P. K. L., Guinot, D. & Davie, P. J. F. (2008) Systema Brachyurorum: Part I. An annotated checklist of extant brachyuran crabs of the world. Raffles Bulletin of Zoology, Supplement 17, 1 - 286.", "Sakai, T. (1979) Description of three new species of crabs of the family Homolidae from Japan. Researches on Crustacea, 9, 1 - 8, 8 - 12, figs. 1 - 3, 1 frontispiece."]}
Band-Limited Coronagraphs using a halftone-dot process: II. Advances and laboratory results for arbitrary telescope apertures
Creators: name: Martinez, P.
name: Dorrer, C.
name: Kasper, M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The band-limited coronagraph is a nearly ideal concept that theoretically enables perfect cancellation of all the light of an on-axis source. Over the past years, several prototypes have been developed and tested in the laboratory, and more emphasis is now on developing optimal technologies that can efficiently deliver the expected high-contrast levels of such a concept. Following the development of an early near-IR demonstrator, we present and discuss the results of a second-generation prototype using halftone-dot technology. We report improvement in the accuracy of the control of the local transmission of the manufactured prototype, which was measured to be less than 1%. This advanced H-band band-limited device demonstrated excellent contrast levels in the laboratory, down to 10-6 at farther angular separations than 3 lambda/D over 24% spectral bandwidth. These performances outperform the ones of our former prototype by more than an order of magnitude and confirm the maturity of the manufacturing process. Current and next generation high-contrast instruments can directly benefit from such capabilities. In this context, we experimentally examine the ability of the band-limited coronagraph to withstand various complex telescope apertures.
description: Accepted in ApJ - under press
Synthesis and coordination chemistry of an N-heterocyclic carbene-containing tridentate ligand
Creators: name: Shaw, Bryan Kenneth
Publisher: name: University of British Columbia
Year: 2012

description: One of the most exciting advances in transition-metal-catalyzed processes has been the move toward use of N-heterocyclic carbenes (NHCs) as ancillary ligands. The variation possible in NHC design is immense with one of the most important design aspects being the incorporation of NHC donors into polydentate arrays to generate tridendate pincer ligands. However, research into this class of compounds was limited until the isolation of the first stable crystalline NHC two decades ago. Therefore, understanding of the organometallic chemistry of this class of compounds remains limited in comparison to the closely related phosphine ligands. Thus, this thesis focuses on the preparation of a di-o-phenylene-bridged tridentate PCP donor set and the reactivity of coordination complexes of late transition metals containing this new ligand system. Incorporation of this tridentate ligand onto the group 10 triad of elements via oxidative addition proceeds smoothly to generate square-planar metal hydride complexes of the form [(PCP)MH][PF6] (where M = Ni(II), Pd(II) and Pt(II). Initiating reactivity studies of this series of complexes exposed a new type of non-innocent ligand ehaviour involving formation of a C-C bond between the carbene atom and an ethyl moiety. Isotopic labeling experiments and DFT calculations are used to provide mechanistic insight into this process that is viewed as a possible source of catalyst deactivation in similar systems. Group 9 metal complexes of rhodium and iridium incorporating tridentate ligand arrays have achieved considerable success in the activation and functionalization of C-H bonds. To examine the reactivity of pincer complexes utilizing a central NHC donor a variety of new rhodium and iridium complexes were synthesized. A rhodium hydride species (PCP)RhH showed catalytic activity in the dehydrogenation of ammonia borane as well as in the ydrosilylation of terminal alkynes. Complexes consisting of both metal centres also exhibited ligand rearrangement processes that challenge the presumed stability of rigid tridentate ligand frameworks.
Re-planning of software product releases
Creators: name: AlBourae, Thamer Ali
Publisher: name: University of Calgary
Year: 2007

description: Bibliography: p. 183-192
description: Most of the time, market-driven software products are characterized by volatile features and instable resources. These changes may jeopardize the software success both functionally and financially. Re-planning software releases by selecting the right subset of features is complex and significant. Through this research, we have a methodology to integrate change requests as they arise through the software development cycle. The main contributions of this research can be listed as follows: 1. A Flexible method for re-planning of software product releases. 2. The change threshold factor is a new contribution to this area of research. 3. We have built a model and described how the re-planning process should be conducted. 4. A genetic algorithm to generate a set of re-planned release alternatives where we can compare between them in terms of value/risk or resources consumption. 5. Initial evaluation of the re-planning method proposed by preforming a hypothetical case study.
Rotational Velocities of Individual Components in Very Low Mass Binaries
Creators: name: Konopacky, Q. M.
name: Ghez, A. M.
name: Fabrycky, D. C.
name: Macintosh, B. A.
name: White, R. J.
name: Barman, T. S.
name: Rice, E. L.
name: Hallinan, G.
name: Duchene, G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present rotational velocities for individual components of eleven very low mass (VLM) binaries with spectral types between M7 and L7.5. These results are based on observations taken with the near-infrared spectrograph, NIRSPEC, and the Keck II laser guide star adaptive optics (LGS AO) system. We find that the observed sources tend to be rapid rotators (vsini > 10 km/s), consistent with previous seeing-limited measurements of VLM objects. The two sources with the largest vsini, LP 349-25B and HD 130948C, are rotating at ~30% of their break up speed, and are among the most rapidly rotating VLM objects known. Furthermore, five binary systems, all with orbital semi-major axes <3.5 AU, have component vsini values that differ by greater than 3sigma. To bring the binary components with discrepant rotational velocities into agreement would require the rotational axes to be inclined with respect to each other, and that at least one component is inclined with respect to the orbital plane. Alternatively, each component could be rotating at a different rate, even though they have similar spectral types. Both differing rotational velocities and inclinations have implications for binary star formation and evolution. We also investigate possible dynamical evolution in the triple system HD 130948A-BC. The close binary brown dwarfs B and C have significantly different vsini values. We demonstrate that components B and C could have been torqued into misalignment by the primary star, A, via orbital precession. Such a scenario can also be applied to another triple system in our sample, GJ 569A-Bab. Interactions such as these may play an important role in the dynamical evolution of very low mass binaries. Finally, we note that two of the binaries with large differences in component vsini, LP 349-25AB and 2MASS 0746+20AB, are also known radio sources.
description: 14 pages, 8 figures. Accepted for publication in ApJ
The Nature of Electronic States in Atomically Thin MoS2 Field-Effect Transistors
Creators: name: Ghatak, Subhamoy
name: Pal, Atindra Nath
name: Ghosh, Arindam
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We present low temperature electrical transport experiments in five field effect transistor devices consisting of monolayer, bilayer and trilayer MoS2 films, mechanically exfoliated onto Si/SiO2 substrate. Our experiments reveal that the electronic states in all films are localized well up to the room temperature over the experimentally accessible range of gate voltage. This manifests in two dimensional (2D) variable range hopping (VRH) at high temperatures, while below \sim 30 K the conductivity displays oscillatory structures in gate voltage arising from resonant tunneling at the localized sites. From the correlation energy (T0) of VRH and gate voltage dependence of conductivity, we suggest that Coulomb potential from trapped charges in the substrate are the dominant source of disorder in MoS2 field effect devices, which leads to carrier localization as well.
description: 10 pages, 5 figures; ACS Nano (2011)
title: The view: gendered views of observation through the creative practice and installation of photographic and moving image
Creators: name: Turner, M.J
Publisher: name: Bath Spa University
Year: 2017

description: This practice-led thesis investigates how a contemporary female practitioner can provoke thought about the impact of observation on the individual, from a gendered viewpoint. Employing purposeful experimentation and visual discovery, questions emerging from practice are raised and examined through exposition and reflective appraisal. Creatively manipulated situations of observation are instigated, through the installation of photography and moving image, to examine the exchange between artwork and audience and to raise awareness of the presence of observation, surveillance and the panoptical gaze. Working from a positive and proactive feminist paradigm, relevant theoretical approaches are used to inform the central concepts drawn from a broad base of texts. The discursive account operates within the context of comparative approaches and methodologies used by contemporary artists, shown in major exhibition venues between 2004 and 2016. The inquiry is investigated through primary research, visual analysis, and direct contact with artists and writers. Selected creative works from both contemporary and historical sources are reviewed, to provide inspiration, methodology and technical detail for particular aspects of content. Through the articulation of practical realisation, a significant contribution of selected and focused work emerges, where the combination of moving and photographic imagery is uniquely fused to create site-specific installation.
Isolation and characterization of recombinant U24, a membrane protein from human herpesvirus type 6
Creators: name: Tait, Andrew Robert
Publisher: name: University of British Columbia
Year: 2011

description: This thesis describes the isolation and characterization of the U24 membrane protein encoded by Human Herpesvirus type-6 (HHV-6), obtained from an E. coli recombinant expression system. HHV-6 infection has been previously associated with the disease multiple sclerosis (MS), and the U24 protein is of interest because it has a seven amino-acid sequence (PRTPPPS) identical to myelin basic protein (MyBP), a candidate auto-antigen in MS. In the first part of this thesis, I describe the methods that were developed to enable milligram quantities of U24 to be isolated and purified from litre cultures of E. coli. Levels of U24 expressed with a maltose binding protein-hexahistidine fusion tag were particularly enhanced by combinations of low temperature, oxidizing conditions, and/or use of minimal media culture. The significance of these results may be considered useful in application to other difficult-to-obtain membrane proteins. Subsequent chapters of this thesis describe testing the recombinant U24 for potential mimicry of MyBP structure and function. Since the polyproline region in MyBP is now being recognized for its potential in cell-signalling roles that relate to myelin sheath development and structural integrity, I hypothesized that U24 may retain some of the same attributes as MyBP on the basis of identical sequence. Results here suggest that U24 can adopt a polyproline type II helix much like MyBP, which is a structural feature important for engaging in protein-protein interactions. Furthermore, the region is also found to represent a PX(T/S)P MAPK phosphorylation motif and PXXP-based Fyn tyrosine kinase SH3 binding domain. These observations are of particular relevance since phosphorylated MyBP is particularly decreased in MS patients, and Fyn is critical to myelin development. Like MyBP, results suggest that U24 can be phosphorylated at the equivalent threonine and is also able to bind to the Fyn-SH3 domain. These results support the possibility that U24 interferes with essential myelin regulation pathways on the basis of its sequence shared with MyBP, thereby contributing to a pathological process. I conclude with a presentation of preliminary NMR structural data for U24, as well as review results from a study of U24 in an animal model system. Future directions are also discussed.
title: From the maternal to the mechanical: the struggle against sentiment in contemporary American motherhood poetry
Creators: name: Militello, J
Publisher: name: Bath Spa University
Year: 2017

description: The purpose of this study is to examine the poems of a small number of contemporary American poets who have worked to undermine poetic traditions of sentimentality that have sometimes figured large in the representation of motherhood. The study focuses on writers who have been formative to my own practice and who have helped me consider a challenge that I have wrestled with in my own writing and personal life. I write about their practices in relation to my own creative project, and to a concern that the more challenging aspects of motherhood not be oppressed. The first two chapters define idealism and sentimentality as factors that have been an important strand of motherhood poetry, explore the ways in which some contemporary American poets have sought to counter these factors in their work, and address the ways in which poets such as Sylvia Plath have examined the loss of maternal identity, which acts as precursor to the depersonalization of the mother in poetry. The thesis then investigates the depersonalization of the maternal figure by addressing the ways in which the mother can be mechanized and objectified in poems, and explores the objectification of the child in the work of several poets, showing how children have been embodied as objects in order to counter the culturally enforced response a child’s presence engenders. These later chapters also explore some of the reasons a poet might objectify the mother and child figure, and address the effects of this approach. As a way of concluding each chapter, the study speaks to the creative manuscript and its contextualization, discussing the ways in which the research has influenced the writing of the poems. The creative portion of the work is a manuscript of poems titled 'The Reproduction Cinema', which also addresses maternal struggle. The study finds that the objectification and depersonalization of mother and child is one important method by which poets wishing to write against more traditional ideas of motherhood might do so. The conclusion suggests that this more inclusive version of a poetics of the maternal experience will help broaden the discourse around the poetry of motherhood.
title: Materials systems and autonomy in electromechanical sound art
Creators: name: Pigott, J
Publisher: name: Bath Spa University
Year: 2017

description: Sound art is a difficult to categorise and broad genre description that draws together modes of creative practice which use sound as a medium or a subject. The field is considered to be critically underrepresented and under-theorised despite an increase of attention and popularity since the 1990s (Licht 2007, 2001, Cox 2009). This is partly as a consequence of an analytical and historical emphasis on textual and conceptual approaches which dominated the arts through the 1970s and 1980s (Cox 2011, 2013). In particular, acknowledgement of the influence of object-based and kinetic sculpture within the field of sound art is found to be inadequate (Chau 2014, Keylin 2015). This thesis presents an original body of sound art practice as a means through which to uncover and explore connections between sound art, experimental composition, kinetic art and sculpture. The term 'electromechanical' is used to identify this work, highlighting its particular concerns with the use of electrically animated or amplified materials. Through the production, exhibition, critical appraisal and contextualisation of the work new observations and distinctions within the field are presented. These include the identification of a 'closed system aesthetic' and the distinction between robotic and process driven approaches to electromechanical sound art. A further contribution to the field consists of a detailed consideration of sound art emerging from an intersection of experimental music and sculptural practices during the 1960s. The original works produced for the project, and their production are documented and described in detail alongside existing canonical and contemporary examples of sound art. Analysis of these works is informed by materialist and object-orientated critical positions, and science and technology studies. The method of art practice as research is described and extended in an original way that encompasses and applies a systems approach to creative practice.
Fe K line complex in the nuclear region of NGC 253
Creators: name: Mitsuishi, Ikuyuki
name: Yamasaki, Noriko Y.
name: Takei, Yoh
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A bright, nearby edge-on starburst galaxy NGC 253 was studied using the Suzaku, XMM and Chandra X-ray observatories. We detected with Suzaku and XMM complex line structure of Fe K, which is resolved into three lines (Fe I at 6.4 keV, Fe XXV at 6.7 keV and Fe XXVI at 7.0 keV) around the center of NGC 253. Especially, the Fe I and Fe XXVI lines are the first clear detections, with a significance of >99.99 % and 99.89 % estimated by a Monte Carlo procedure. Imaging spectroscopy with Chandra revealed that the emission is distributed in ~60 arcsec^2 region around the nucleus, which suggests that the source is not only the buried AGN. The flux of highly ionized Fe lines can be explained by the accumulation of 10-1000 supernova remnants that are the result of high starforming activity, while the Fe I line flux is consistent with the fluorescent line emission expected with the molecular clouds in the region.
description: Accepted for publication in ApJL
title: Foundations of research in creative computing
Creators: name: Zhang, L
Publisher: name: Bath Spa University
Year: 2017

description: Human creativity needs improvement in contemporary society. Because of fast development and pervasive utilisation, computing has been a loyal servant to support human creativity. It is not only utilised to facilitate creativity research, but also leveraged to assist creative activities in everyday life. However, due to increasingly complicated human life and ever-evolving nature of computer, up to now, people have never stopped exploring the great potentials of computing to facilitate human creativity. As a result, various kinds of new concepts in computing are continuously emerging dedicating to make contributions to human creativity. Creative Computing is one of the promising ones. Its most important advantage is inspiring a novel approach to facilitating human creativity. By making computing itself become creative, the services supplied by Creative Computing can be more active and better reconcile the contradiction between subjective creativity and objective computing. Instead of imitating or duplicating human creativity, the core idea of Creative Computing is to leverage the uniting power of knowledge to tackle problems in computing field to facilitate human creativity. My research aims to consolidate Creative Computing as a knowledge discipline to facilitate its development. As Creative Computing is a new field, several important issues are required to be studied. First things first are the fundamental issues. In order to do that, my research devotes to proposing kind of framework of Creative Computing by consolidating it as a knowledge discipline. Various crucial elements of Creative Computing will be studied and described by this thesis. It is hoped that the results of my research can be able to provide valuable suggestions for the following researchers of Creative Computing.
Biomarkers of fatty acids and risk of type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies
Creators: name: Chen, Gengdong
name: Li, Yan
name: Zeng, Fangfang
name: Deng, Guifang
name: Liang, Jingjing
name: Wang, Jue
name: Su, Yixiang
name: Chen, Yuming
name: Mao, Limei
name: Liu, Zhengping
name: Bao, Wei
name: Zhang, Zheqing
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: We aimed to quantify and generate comprehensive evidence on the associations of different fatty acids (FAs) with the risk of type 2 diabetes mellitus (T2DM). PubMed, MEDLINE, and Embase were searched for prospective cohort studies that examined the association between FA biomarkers and the risk of T2DM published before 18 May 2020. Random-effects meta-analyses of the effects of FA concentration on T2DM were performed. Thirty-three studies involving 95,810 adults (19,904 cases) were included. Divergent associations of different types of FAs with type 2 diabetes were observed. The pooled relative risk (RRs) of T2DM comparing the top versus the bottom tertile of saturated FAs (C14:0, C16:0, C18:0, total saturated FAs), monounsaturated FA (C16:1 n-7), polyunsaturated FA (C20:3 n-6, C22:4 n-6), and Δ-6-desaturase activities ranged from 1.19 to 1.80. Interestingly, unlike previous studies, we found a negative correlation between odd-chain saturated FAs (C15:0, C17:0), trans-FAs (trans-C16:1 n-7), total n-6, Δ-5-desaturase activities and risk of T2DM. The pooled RRs of T2DM comparing the top versus the bottom tertile of these FAs ranged from 0.62 to 0.78. No associations with T2DM were observed for the other FAs. Considerable heterogeneity was observed in our study, and no definitive conclusions can be made until further investigation has been carried out.
benchdamic: Benchmarking of Differential abundance methods on Microbiome data
Creators: name: Calgaro, Matteo
name: Vitulo, Nicola
name: Romualdi, Chiara
name: Risso, Davide
name: Waldron, Levi
Publisher: name: F1000 Research Limited
Year: 2020

description: The correct identification of differentially abundant microbial taxa between experimental conditions is a methodological and computational challenge. Recent work has produced methods to deal with the high sparsity and compositionality characteristic of microbiome data, but independent benchmarks comparing these to alternatives developed for RNA-seq data analysis are lacking. The slides present a package which is currently under development. It consists of a framework to help scientists make an informed choice of analysis methods in a dataset-specific way.
title: A semantic web based meta search engine
Creators: name: Li, S
Publisher: name: Bath Spa University
Year: 2017

description: With the rapid development of economy and technology, people who are influenced by the era pay more attention to the Internet. Creative computing is a relatively new research area, for enhancing human creativity through requiring computing itself to be creative. It involves the Internet, web language, art, humanities and other areas. It motivates creative thinking during the process of study. The aim of my research is to develop a targeted and personalised a meta search engine (MSE) based on the semantic web technology and at the same time, to explore whether it will resolve problems and create applied value for a group of people. The semantic web integrates Internet into an integral database by adding meta data which can be acknowledged by computer. By adding meta data, all content will be re-graded into data by document unit. As a result, data will cover meanings in different semantics and can generate certain logical relationship. On account of this concept, after receiving searching needs, Meta Search Engine hunts on multiple search engines and return result to users. It mainly focuses on improving searching speed, intelligently handling of search result and personalising searching function. What is more, recall ratio and precision ratio is high with increasing friendliness on users’ retrieval surface. The author can personally provide targeted search of a restricted field by compiling algorithm of metadata search engine. Compared with the present search engines, the Writer’s Portal that I am building is more personalised. Writer’s Portal can provide the writers with more information on funding opportunities and scholarship support, etc., in order that writer could find a variety of aids on finance. Therefore, this is a very practical and a focused project. It can also fully show the characteristics of accuracy and personalisation of the meta search engines.
Kinematic Cusps With Two Missing Particles I: Antler Decay Topology
Creators: name: Han, Tao
name: Kim, Ian-Woo
name: Song, Jeonghyeon
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The kinematics of a final state system with two invisible particles and two visible particles can develop cusped peak structures. This happens when the system has a fixed invariant mass (such as from a narrow resonant particle decay or with a fixed collision c.m. energy) and undergoes decays of two on-shell intermediate particles. Focusing on the "antler decay topology", we derive general analytic expressions for the invariant mass distribution and the kinematic cusp position. The sharp cusp peaks and the endpoint positions can help to determine the masses of the missing particles and the intermediate particles. We also consider transverse momentum variables and angular variables. In various distributions the kinematic cusp peaks are present and pronounced. We also study the effects on such kinematic cusp structures from realistic considerations including finite decay widths, the longitudinal boost of the system, and spin correlations.
description: references added, 40 pages with 19 figures
title: The neo-monument : monuments of dissent and their emergence in western culture in the late 20th and early 21st century
Creators: name: Clark, D
Publisher: name: Bath Spa University
Year: 2017

description: This research addresses contemporary art practice and the monument in the 21st Century. In doing this, the notion of the monument in this research is considered to be an art object, conceived by artist(s) to memorialise, remind, instruct, or warn the public, as in the original derivation of the word ‘monument’. The late 20th Century started to see, in part, the democratisation of the monument. Here I propose that he traditional monument has always been political and a tool of the ruling elite. However, where previously the ‘Establishment’ influence was absolute, in recent times, some artists have sought creative space to place more controversial work in the public arena. Released from the restraints of authority, new monuments have been created that question the vicissitudes of our existence and it is this field of artistic practice that is the central issue in this research. Unlike monuments of the past, although they might have sprung from an historical event, these new monuments are less about memorial and more about the present. Often they ask demanding questions of our culture, our governments and of us, the people. Significantly, they are ‘monuments of dissent’ and because of their rejection of the status quo, it is proposed here that they should be termed ‘Neo-Monuments’. Whereas traditional monuments were normally to be found on the street, in the square or park, these spaces have now been augmented by an increasing number of publicly accessed galleries. We will see that there is now a more open-minded approach to critical, questioning even provocative monuments, and that we are seeing them both in galleries and in the public milieu. It will be argued that they are however still viable forms of communication. This research is informed by the creation, exploration, experimentation and analysis of my own art practice. Conclusions gained from this practice will be used to inform this research. Additionally, case studies of other artists engaged with the form and development of the neo-monument will be analysed to understand their rationale, and from this to determine what sets their work apart and allows them to be regarded as a neo-monument. This research will reflect on art-monuments created from the last quarter of the 20th Century until the present.