cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Wirkungskontrolle Revitalisierung an der Bünz, oberhalb HRB Wohlen : Indikator-Set 1 - Habitatvielfalt
Creators: name: Rutz, Cornel
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2024
Subjects: Wirkungskontrolle Revitalisierung
Indikator-Set 1
Habitatvielfalt
Bünz
HRB Wohlen
Sohlenstruktur
Uferstruktur
Wassertiefe
Fliessgeschwindigkeit
Unterstandsangebot
Substrat
Geschiebe
333: Bodenwirtschaft und Ressourcen

description: Zertifikatarbeit CAS Gewässerrenaturierung (GER)
description: Mit Revitalisierungen sollen Fliessgewässer, welche sich hinsichtlich ihrer natürlichen Funktionen in beeinträchtigtem Zustand befinden, wieder in einen naturnahen Zustand überführt werden. Dies führt zur Steigerung des Hochwasserschutzes und der Wasserqualität, der Schaffung von diversen Lebensräumen und attraktiven Erholungsgebieten. Das im oberen Bünztal vorhandene Defizit hinsichtlich Hochwasserschutz führte im Jahr 2017 zum Bau eines Hochwasserrückhaltebeckens (HRB) in Wohlen und der damit verbundenen Revitalisierung der Bünz ab dem HRB bis an die Siedlungsgrenze von Waltenschwil. Im Rahmen dieser Zertifikatsarbeit wurde exemplarisch mittels Indikator-Set 1 Habitatvielfalt der Praxisdokumentation Wirkungskontrolle untersucht, inwieweit sich die Vielfalt an Habitaten durch die Revitalisierung gegenüber dem Vorher-Zustand verändert hat. Da keine Vorher- Aufnahmen in diesem Abschnitt existieren, erfolgte der Vergleich anhand eines reinen Nachher-Vergleichs mittels angrenzender, kanalisierten Kontrollstrecke. Darüber hinaus wurden die Werte einem natürlich klassifizierten Abschnitt der Bünz - der Bünzaue - gegenübergestellt. Die Revitalisierungsmassnahmen führten im Revitalisierungsabschnitt resp. im Unterabschnitt Revitalisierung im Vergleich zum kanalisierten Kontrollabschnitt resp. dem Unterabschnitt Kontrolle zu einer mehrheitlich signifikanten Steigerung der Werte der sechs Indikatoren. Mit dem Vergleich der Werte kann festgehalten werden, dass die Revitalisierung im Vergleich zum Kontrollabschnitt eine deutlich höhere Habitatvielfalt aufweist. Hingegen ist die natürliche Referenzstrecke gegenüber der Revitalisierungsabschnitte bei beinahe allen Indikatoren klar besser bewertet. Ein Ausblick gibt Anhaltspunkte wie kanalisierte Fliessgewässer aufgewertet und mit welchen Massnahmen zukünftige Revitalisierungen hinsichtlich deren Wirkung optimiert werden können.
Additional file 5 of Protective role of extracellular vesicles against oxidative DNA damage
Creators: name: Ribas-Maynou, Jordi
name: Parra, Ana
name: Martínez-Díaz, Pablo
name: Rubio, Camila Peres
name: Lucas, Xiomara
name: Yeste, Marc
name: Roca, Jordi
name: Barranco, Isabel
Publisher: name: figshare
Year: 2025
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 5: Table S1. Enzymaticandnon-enzymaticantioxidant capacity measured in non-permeabilized and permeabilized seminal extracellular vesicles.
Lasset die Spiele beginnen!
Creators: name: van Meel, Dorit
Publisher: name: Hochschule für Agrar- und Umweltpädagogik
Year: 2023
Subjects: Interreg
Zukunftsgrün
Spiel ohne Grenzen
Klimaschutz
Biodiversität
333.7: Landflächen, Naturerholungsgebiete

description: 2023 startete das Interreg-Projekt “Zukunftsgrün“. Bis 2026 stossen die Projektpartner innerhalb des Programmgebietes Alpenrhein-Bodensee-Hochrhein Vernetzungs- und Entwicklungsprozesse an. Eine der Initiativen ist das “Spiel ohne Grenzen! Zukunftsgrün“.
Sozialraumorientierte Offene Jugendarbeit und die Verschränkung virtueller und physischer Räume
Creators: name: Brandenberg, Elias
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2024
Subjects: Jugendararbeit
Virtueller Raum
Sozialraumorientierung
Offene Kinder- und Jugendarbeit
Verschränkung virtueller und physischer Räume
305: Personengruppen (Alter, Herkunft, Geschlecht, Einkommen)
307: Gemeinschaften
362.7: Jugendhilfe

description: Jugendliche sind in ihrer Freizeitgestaltung auf leicht zugängliche Erfahrungs-, Rückzugs- und Freiräume angewiesen. Heute müssen virtuelle Räume als feste Bestandteile jugendlicher Sozialräume verstanden werden (Schwerthelm, 2021). Mobile Geräte dienen als Schnittstelle zwischen virtuellen und physischen Räumen, wobei eine ständige Gleichzeitigkeit der Nutzung und Platzierung stattfindet. Die Offene Jugendarbeit bewegt sich oft nur am Rande in dieser Verflechtung (Mayrhofer & Neuburg, 2019). Virtuelle Räume werden häufig negativ als Parallelwelt oder Gefahrenraum diffamiert und die entsprechenden Erfahrungen nicht als Teil jugendlicher Realitäten anerkannt. Daher ist eine Erweiterung des Sozialraumverständnis, das sich an den Lebensrealitäten heutiger Jugendlicher orientiert, auch in diesem Handlungsfeld unumgänglich.
Das durch den NFP 80 finanzierte Forschungsprojekt «Jugend und Raum» untersucht die Nutzung virtueller und physischer Räume durch Jugendliche. Im Rahmen meiner Dissertation verfolge ich ergänzend das Ziel, Hinweise für eine bedarfsgerechte sozialraumorientierte Offenen Jugendarbeit zu erarbeiten. Zum Zeitpunkt des Kongresses wird die erste Runde der qualitativen Erhebung mit Jugendlichen (u.a. Gruppenworkshops, Sozialraumbegehungen) sowie der Expert:inneninterviews mit Fachpersonen der Offenen Jugendarbeit abgeschlossen sein und erste Ergebnisse können präsentiert werden.
The Charles W. Morgan, the World's Oldest Whaling Vessel, 1913
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 1913
Subjects: Shipwrecks
Boat & ship industry
Ships
Whaling
Whales

description: This photograph shows the Charles W. Morgan in 1913, the World's Oldest Whaling Vessel and second oldest commercial vessel to the USS Constitution. This whaling vessel was built in 1841 and currently on exhibit at the Mystic Seaport Museum in Connecticut.
GEMS : a generalizable GNN framework for protein-ligand binding affinity prediction through robust data filtering and language model integration
Creators: name: Graber, David
name: Stockinger, Peter
name: Meyer, Fabian
name: Mishra, Siddhartha
name: Horn, Claus
name: Buller, Rebecca
Publisher: name: bioRxiv
Year: 2024
Subjects: Binding affinity prediction
Protein-ligand scoring
Scoring function
Data leakage
Structure-based drug design
Graph neural network
Transfer learning
Computational drug discovery
Protein language model
Large language model
005: Computerprogrammierung, Programme und Daten
615: Pharmakologie und Therapeutik
660.6: Biotechnologie

description: The field of computational drug design requires accurate scoring functions to predict binding affinities for protein-ligand interactions. However, train-test data leakage between the PDBbind database and the CASF benchmark datasets has significantly inflated the performance metrics of currently available deep-learning-based binding affinity prediction models, leading to overestimation of their generalization capabilities. We address this issue by proposing PDBbind CleanSplit, a training dataset curated by a novel structure-based filtering algorithm that eliminates train-test data leakage as well as redundancies within the training set. Retraining the current best-performing model on CleanSplit caused its benchmark performance to drop to uncompetitive levels, indicating that the performance of existing models is largely driven by data leakage. In contrast, our graph neural network model for efficient molecular scoring (GEMS) maintains high benchmark performance when trained on CleanSplit. Leveraging a sparse graph modeling of protein-ligand interactions and transfer learning from language models, GEMS is able to generalize to strictly independent test datasets.
Der Zusammenhang zwischen der Unternehmensperformance und der Mitarbeiterfluktuation : eine empirische Analyse der Aktienperformance
Creators: name: Geia, Hassan
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2024
Subjects: 332: Finanzwirtschaft

description: Die Mitarbeiterfluktuation ist ein nicht-finanzieller Leistungsindikator, dessen Bedeutung für die Unternehmensleistung in der Literatur ein wichtiges Thema ist.
Anhand von Daten US-amerikanischer und europäischer börsennotierter Unternehmen wurde der Zusammenhang zwischen Mitarbeiterfluktuation (Absolut und ESG Fluktuation Score), künftiger finanzieller Leistung (ROA; ROE) und Aktienperformance untersucht.
In der Masterarbeit wurde ein negativer Zusammenhang zwischen der Mitarbeiterfluktuation und der Aktienperformance im selben Jahr festgestellt nimmt im folgenden Jahr eine ausgeprägtere Form an. Über einen Zeitraum von zwei Jahren ist die Beziehung zur Aktienkursentwicklung immer noch vorhanden, aber schwach. Andererseits wurde in der Arbeit ein positiver Zusammenhang mit dem ESG Fluktuation Score im selben Jahr festgestellt, der im darauffolgenden Jahr stärker wird und im zweiten Jahr bestehen bleibt, sich aber abschwächt. Zudem waren ESG Fluktuation Score in dieser Beziehung von grösserer Bedeutung, was darauf hindeutet, dass die Anleger diese Kennzahl in ihre Prognosen einbeziehen sollten.
Die Korrelation zwischen dieser Kennzahl und der ROA war im selben Jahr eindeutig, schwächte sich jedoch im darauffolgenden Jahr ab und wurde im zweiten Jahr wieder stärker. Während im ersten Jahr keine Beziehung zur ROE festgestellt werden kann, wird sie im nächsten Jahr deutlicher und im zweiten Jahr stärker.
Die durchgeführte Untersuchung kommt zu dem Schluss, dass ein Zusammenhang zwischen der Mitarbeiterfluktuation und der künftigen finanziellen Performance sowie der Aktienperformance besteht.
Green open access policy template : a do it yourself policy guideline
Creators: name: Andres, Valérie
name: Brunner, Cornelia
name: Corredera Nilsson, Enrique
name: Flieg, Julia
name: Moritz, Andrea Marlen
name: Reymermier, Hélène
name: Trautwein, Clemens
Publisher: name: Zenodo
Year: 2024
Subjects: Green open access
Publisher
Publication
Creative commons license
License
Self-archiving
020: Bibliotheks- und Informationswissenschaft
070: Nachrichtenmedien, Journalismus und Verlagswesen

description: This document has versions in other languages
German: 10.5281/zenodo.13844165 (DOI)
French: 10.5281/zenodo.13844145 (DOI)
description: This template helps journal editors or librarians who want to propose a Green Open Access Policy to a journal to design one. By letting you select between options, you can tailor the policy to the needs of the journal.
Once the journal has published the policy, please send us the information for inclusion in the GOAL database: https://goal.zhaw.ch
Recent progress in our understanding of the degradation of carbon-based electrodes in vanadium redox flow batteries : current status and next steps
Creators: name: Remmler, Nico
name: Bron, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 540

description: This mini-review summarises and discusses recent findings form the literature on the degradation of carbon-based electrodes for vanadium redox flow batteries (VRFBs). It becomes evident that the focus of current investigations is on carbon paper, carbon felt and graphite felt electrodes, which is understandable from a practical point of view. However, the structural complexity of these materials often prohibits doubtless attribution of observed performance reduction (or increase) to changes in the electrode materials. Among the discussed major causes for degradation are formation or change of surface functional groups, changes in the carbon sp2/sp3 ratio, intercalation of ions as well as formation of inhibiting adsorbates. In order to gain deeper insight into the changes of carbon electrodes in VRFBs under relevant operation conditions, the authors suggest reducing complexity of the investigated materials and applying in situ-studies under well-defined and controllable conditions on model electrodes. These studies then should be extended towards more practical systems and may finally help to reduce degradation phenomena including enhanced overvoltages and thus could improve cycling and energy efficiency as well as long-term stability of vanadium redox flow batteries.
The effect of upright posture on left atrial strain in competitive athletes
Creators: name: Kandels, Joscha
name: Stöbe, Stephan
name: Marshall, Robert Percy
name: Hagendorff, Andreas
name: Metze, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background: Left atrial strain (LAS) assessment by speckle tracking echocardiography (STE) has been shown to be a remarkable means of quantifying LA function as an early marker of LV pathology. As exercise testing is also performed on a treadmill, the aim of this study was to investigate the effect of upright posture on LAS in healthy athletes. Methods: Fifty male athletes (mean age 25.7 ± 7.3 years) underwent transthoracic echocardiography (TTE) in the upright and left lateral positions. In addition to the conventional echocardiographic parameters, in all athletes, LA conduction strain (LAScd), contraction strain (LASct), reservoir strain (LASr), and maximum LA volume (LAVmax) were assessed by STE in both positions. Results: Comparing upright posture and the left lateral position, LAScd (−14.0 ± 5.9% vs. −27.4 ± 7.1%; p < 0.001), LASct (−4.6 ± 3.5% vs. −11.3 ± 4.1%; p < 0.001), LASr (18.7 ± 7.6% vs. 38.7 ± 8.0%; p < 0.001), and LAVmax (24.4 ± 8.8% vs. 50.0 ± 14.2%) differed significantly. Conclusions: Upright posture has a significant effect on LA deformation, with decreased LAScd, LASct, and LASr. The results of this study contribute to the understanding of athletes’ hearts and must be considered when performing echocardiography in healthy athletes on a treadmill.
Energetics and dynamics of the proton shuttle of carbonic anhydrase II
Creators: name: Raum, Heiner N.
name: Fisher, Suzanne Zoë
name: Weininger, Ulrich
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 530

description: Human carbonic anhydrase II catalyzes the reversible reaction of carbon dioxide and water to form bicarbonate and a proton. His64-mediated proton shuttling between the active site and the bulk solvent is rate limiting. Here we investigate the protonation behavior of His64 as well as its structural and dynamic features in a pH dependent way. We derive two pKa values for His64, 6.25 and 7.60, that we were able to assign to its inward and outward conformation. Furthermore, we show that His64 exists in both conformations equally, independent of pH. Both conformations display an equal distribution of their two neutral tautomeric states. The life time of each conformation is short and both states display high flexibility within their orientation. Therefore, His64 is never static, but rather poised to change conformation. These findings support an energetic, dynamic and solution ensemble-based framework for the high enzymatic activity of human carbonic anhydrase II.
Additional file 1 of WBP1 regulates mitochondrial function and ferroptosis to modulate chemoresistance in colorectal cancer
Creators: name: Wang, Yang
name: Qi, Dachuan
name: Ge, Guijie
name: Cao, Ning
name: Liu, Xiangdong
name: Zhu, Na
name: Li, Feng
name: Huang, Xiang
name: Yu, Kui
name: Zheng, Jinzhou
name: Wang, Daoheng
name: Yao, Wenyan
name: Chen, Lili
name: Dong, Ziyang
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1
All-oxide metasurfaces formed by synchronized local ionic gating
Creators: name: Han, Hyeon
name: Sharma, Arpit
name: Yoon, Jiho
name: Wang, Zhong
name: Körner, Chris
name: Deniz, Hakan
name: Sharma, Ankit Kumar
name: Li, Fan
name: Sturm, Chris
name: Woltersdorf, Georg
name: Parkin, Stuart S. P.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 530

description: Ionic gating of oxide thin films has emerged as a novel way of manipulating the properties of thin films. Most studies are carried out on single devices with a three-terminal configuration, but, by exploring the electrokinetics during the ionic gating, such a configuration with initially insulating films leads to a highly non-uniform gating response of individual devices within large arrays of the devices. It is shown that such an issue can be circumvented by the formation of a uniform charge potential by the use of a thin conducting underlayer. This synchronized local ionic gating allows for the simultaneous manipulation of the electrical, magnetic, and/or optical properties of large arrays of devices. Designer metasurfaces formed in this way from SrCoO2.5 thin films display an anomalous optical reflection of light that relies on the uniform and coherent response of all the devices. Beyond oxides, almost any material whose properties can be controlled by the addition or removal of ions via gating can form novel metasurfaces using this technique. These findings provide insights into the electrokinetics of ionic gating and a wide range of applications using synchronized local ionic gating.
Lehrer ohne Worte
Creators: name: van Meel, Dorit
Publisher: name: Hochschule für Agrar- und Umweltpädagogik
Year: 2024
Subjects: Kommunikation
Pferd
Green Care
Tiergestützte Intervention
615: Pharmakologie und Therapeutik

description: Wenige Verbindungen zwischen Mensch und Tier sind so vielfältig wie die zu Pferden. Einer der Gründe, weshalb sie heutzutage im Rahmen von Green Care Angeboten vielfältige Möglichkeiten bieten, ist ihre Fähigkeit, sprach- und kulturunabhängig zu kommunizieren.
การจัดการความรู้เพื่อสร้างสรรค์คุณค่าผ้าจกราชบุรี
Creators: name: เสรี เพิ่มชาติ; อัญชลี จันทาโภ; วราภรณ์ ลิ้มเปรมวัฒนา; พฤกษ์ จิรสัตยาภรณ์
Publisher: name: สมศักดิ์การพิมพ์
Year: 2556
Subjects: การสร้างสรรค์คุณค่า; ผ้าจกราชบุรี; การจัดการความรู้

description: วารสารการพัฒนาชุมชนและคุณภาพชีวิต, 1, 3
Suppl_SERPIN – Supplemental material for SERPINA9 and SERPINB2: Novel Cartilage Lineage Differentiation Markers of Human Mesenchymal Stem Cells with Kartogenin
Creators: name: Granados-Montiel, Julio
name: Cruz-Lemini, Monica
name: Rangel-Escareño, Claudia
name: Martinez-Nava, Gabriela
name: Landa-Solis, Carlos
name: Gomez-Garcia, Ricardo
name: Lopez-Reyes, Alberto
name: Espinosa-Gutierrez, Alejandro
name: Ibarra, Clemente
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, Suppl_SERPIN for SERPINA9 and SERPINB2: Novel Cartilage Lineage Differentiation Markers of Human Mesenchymal Stem Cells with Kartogenin by Julio Granados-Montiel, Monica Cruz-Lemini, Claudia Rangel-Escareño, Gabriela Martinez-Nava, Carlos Landa-Solis, Ricardo Gomez-Garcia, Alberto Lopez-Reyes, Alejandro Espinosa-Gutierrez and Clemente Ibarra in CARTILAGE
Ramie (Boehmeria nivea) – a local grown raw material for textiles and fibre composites for Europe? / FRESH STORMING – a suitable process chain to establish bast fibres as textile raw material for the future?
Creators: name: Leupin, Marianne
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2024
Subjects: 630: Landwirtschaft

description: The ramie cultivation trials in Wädenswil showed that with suitable ramie clones and only two harvests it is quite possible to keep up with or even exceed the yield of bast ribbons in the original cultivation regions. Compared to cotton with a global average fibre yield of 750 kg/ha up to 4x more ramie fibres per hectare could be obtained.
Additional file 1 of Part II: understanding pain in pigs—pain assessment in pigs with spontaneously occurring diseases or injuries
Creators: name: Kschonek, Julia
name: Deters, Kathrin
name: Miller, Moana
name: Reinmold, Jennifer
name: Twele, Lara
name: Emmerich, Ilka
name: Kästner, Sabine
name: Kemper, Nicole
name: Kreienbrock, Lothar
name: Hennig-Pauka, Isabel
name: Wendt, Michael
name: Beilage, Elisabeth grosse
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1
antwi-agyei-supplement – Supplemental material for Toilets for tenants: a cooperative approach to sanitation bye-law enforcement in Ga West, Accra
Creators: name: Antwi-Agyei, Prince
name: Monney, Isaac
name: Bismark Dwumfour-Asare
name: Cavill, Sue
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Economics
subject: 120599 Urban and Regional Planning not elsewhere classified
subject: FOS: Social and economic geography

description: Supplemental material, antwi-agyei-supplement for Toilets for tenants: a cooperative approach to sanitation bye-law enforcement in Ga West, Accra by Prince Antwi-Agyei, Isaac Monney, Bismark Dwumfour-Asare and Sue Cavill in Environment & Urbanization
Effect of different glucose levels and glycation on meningioma cell migration and invasion
Creators: name: Selke, Philipp
name: Strauss, Christian
name: Horstkorte, Rüdiger
name: Scheer, Maximilian
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 540

description: Meningiomas are predominantly benign tumors, but there are also malignant forms that are associated with a poor prognosis. Like almost all tumors, meningiomas metabolize glucose as part of aerobic glycolysis (Warburg effect) for energy supply, so there are attempts to influence the prognosis of tumor diseases using a glucose-reduced diet. This altered metabolism leads to so called hallmarks of cancer, such as glycation and glycosylation. In this study, we investigated the influence of low (3 mM), normal (5.5 mM) and high glucose (15 mM) on a malignant meningioma cell line (IOMM-Lee, WHO grade 3). In addition, the influence of methylglyoxal, a by-product of glycolysis and a precursor for glycation, was investigated. Impedance-based methods (ECIS and RTCA) were used to study migration and invasion, and immunoblotting was used to analyze the expression of proteins relevant to these processes, such as focal adhesion kinase (FAK), merlin or integrin ß1. We were able to show that low glucose reduced the invasive potential of the cells, which was associated with a reduced amount of sialic acid. Under high glucose, barrier function was impaired and adhesion decreased, which correlated with a decreased expression of FAK.
DS_10.1177_0094582X18807488 – Supplemental material for The Governing Left in Uruguay (2005–2015): A Participatory Democratic Experiment
Creators: name: Bentancur, Nicolás
name: Busquets, José Miguel
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, DS_10.1177_0094582X18807488 for The Governing Left in Uruguay (2005–2015): A Participatory Democratic Experiment by Nicolás Bentancur and José Miguel Busquets in Latin American Perspectives
Experiences and life circumstances of unintentionally pregnant women affected by intimate partner violence-stress factors, resources, healthcare structures and needs : a scoping review protocol
Creators: name: Winter, Kristina
name: Niemann, Jana
name: Jepsen, Dennis
name: Brzank, Petra
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: This scoping review outlines the current understanding, challenges, available resources, and healthcare needs of women affected by intimate partner violence (IPV) who experience unintended pregnancy (UP). UPs are defined as unwanted, unplanned, or mistimed pregnancies. The impact of UP is multifaceted and carries several additional risks, particularly for women who experience IPV. The experiences and living conditions, including (mental) burdens, resources, care structures, and the needs of unintentionally pregnant women who have experienced IPV, remain mostly unexplored. The review will include the following criteria: (i) reproductive-aged women who have experienced IPV and UP; (ii) publications that provide detailed accounts of the experiences, circumstances, and/or needs of women with UP who have experienced IPV. This study will utilize the JBI methodology for scoping reviews and follow the PRISMA Protocol for Scoping Reviews (PRISMA-ScR). A total of 2,325 papers and gray literature published from 2000 to the present were identified. 1,539 literature items were included in the title and abstract screening. Two researchers will independently choose studies, perform data extraction, and perform data synthesis. Quantitative data will be narratively summarized and qualitative data will be analyzed using thematic analysis. The findings will identify research gaps and provide insights into an important topic of reproductive healthcare and the (mental) health situation of a particularly vulnerable group. This will be useful in defining indications for researchers, professionals, and policymakers in public, mental, and reproductive health to conceptualize interdisciplinary and empirical healthcare support for affected women.
A guide to AI : understanding the technology, applying it successfully, and shaping a positive future
Creators: name: Stadelmann, Thilo
name: Prabhu Siddhartha, Guptara
Publisher: name: Global Resilience Publishing
Year: 2025
Subjects: Artificial intelligence
Machine learning
Deep learning
AI and society
006: Spezielle Computerverfahren

description: If artificial intelligence were a road, what would the signs look like? ’No Speed Limit’ / ’Caution, Danger Ahead’ / ’Toll Station Ahead’ / ’Start of Multi-Lane Construction’? Such narratives are indeed told about AI, sometimes contradicting each other. Which ones you trust is crucial for the future - in business, society, and private life. Therefore, we take an analytical look at the state of this road and clear
up the forest of signs. We first explore the scientific, philosophical, business, and societal levels of the metaphor ’artificial intelligence’ to get closer to its core. We examine the underlying technology and look at primary fields of application and frequently mentioned risks. From this, we derive concrete options for dealing with and implementing AI, and provide an outlook on our future.
Levosimendan increases the phosphorylation state of phospholamban in the isolated human atrium
Creators: name: Abella, Lina Maria Rayo
name: Hoffmann, Robert
name: Neumann, Joachim
name: Hofmann, Britt
name: Gergs, Ulrich
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Levosimendan (up to 10 µM) given alone failed to increase force of contraction in isolated electrically stimulated (1 Hz) left atrial (LA) preparations from wild-type mice. Only in the additional presence of 0.1 µM rolipram, an inhibitor of the activity of phosphodiesterase IV, levosimendan increased force of contraction in LA and increased the phosphorylation state of phospholamban at amino acid serine 16. Levosimendan alone increased the beating rate in isolated spontaneously beating right atrial preparations from mice and this effect was potentiated by rolipram. The positive inotropic and the positive chronotropic effects of levosimendan in mouse atrial preparations were attenuated by 10 µM propranolol. Finally, we studied the contractile effects of levosimendan in isolated electrically stimulated (1 Hz) right atrial preparations from the human atrium (HAP), obtained during cardiac surgery. We detected concentration-dependent positive inotropic effects of levosimendan alone that reached plateau at 1 µM levosimendan in HAP (n = 11). Levosimendan shortened time of tension relaxation in HAP. Cilostamide (1 µM), an inhibitor of phosphodiesterase III, or propranolol (10 µM) blocked the positive inotropic effect of levosimendan in HAP. Levosimendan (1 µM) alone increased in HAP the phosphorylation state of phospholamban. In conclusion, we present evidence that levosimendan acts via phosphodiesterase III inhibition in the human atrium leading to phospholamban phosphorylation and thus explaining the positive inotropic effects of levosimendan in HAP.
Supplementary document for Cationic complexes enhanced C-H stimulated Raman scattering in naphthalene-benzene solution - 6509965.pdf
Creators: name: du, hua
name: Xue, Ruqing
name: xu, xueliang
name: sun, chenglin
name: Zhang, Wei
name: Fang, Wenhui
name: men, zhiwei
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Raman spectroscopy, Forward beam cross-sectional image
Der private Sicherheitssektor in der Schweiz : Ergebnisse einer Befragung von Schweizerischen Sicherheitsdienstleistungs-Unternehmen
Creators: name: Baier, Dirk
name: Suvada, Adrienne
name: Merdzanovic, Adis
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2025
Subjects: 363: Umwelt- und Sicherheitsprobleme

description: Private Sicherheitsdienstleistungs-Unternehmen in der Schweiz leisten einen wichtigen Beitrag zu einem sicheren Wirtschafts- und Lebensraum in der Eidgenossenschaft. Dieser Beitrag wird insgesamt noch wenig wahrgenommen und wertgeschätzt. Eine Folge davon ist, dass dieser Sektor unter Personalmangel leidet. Potenzielle Kandidatinnen und Kandidaten werden durch das fehlende Ansehen der Branche abgeschreckt. Problematisch ist zudem, dass die Datenlage zu diesem Sektor sehr schlecht ist. Dabei erwirtschaften private Wach- und Sicherheitsdienste einen Umsatz von über einer Milliarde Schweizer Franken jährlich. Der private Sektor verzeichnete seit Anfang der 2000er-Jahre im Kontext einer erhöhten Instabilität ein starkes Wachstum. Zwischen 2012 und 2019 stieg in der Schweiz die Anzahl an Beschäftigten im Sektor von 19'000 auf über 23'500; auch aktuell sind in diesem Sektor ca. 23'000 Personen beschäftigt, was bedeutet, dass es mehr private Sicherheitskräfte als Polizistinnen und Polizisten (ca. 20'000) in der Schweiz gibt. Insofern die Datenlage zu diesem über 750 Unternehmen umfassenden Sektor unzureichend ist, war zentrales Ziel der hier vorgestellten Studie, Rahmendaten auf dem Weg einer Befragung dieser Unternehmen zu erarbeiten. Dadurch wird der Sektor sichtbarer; die aktuelle Situation, Trends und mögliche Herausforderungen dieses Sektors können damit besser aufgezeigt werden.
Relation von Norm und Praxis erziehungswissenschaftlicher Zugänge zu Inklusion und Partizipation in der Grundschule
Creators: name: Sturm, Tanja
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 371

description: Der Beitrag gibt einen Einblick in die Konzeption der Relation von Normen und Praxis von Inklusion und Partizipation, die im aktuellen erziehungswissenschaftlichen Diskurs der Grundschulpädagogik in unterschiedlichen aufgerufenen Zugängen beschrieben werden. Exemplarisch werden die Inklusions- und Partizipationsverständnisse der evidenzbasierten Bildungsforschung, der auf Foucault aufbauenden Dis_Ability Studies und der Praxeologischen Wissenssoziologie vergleichend vorgestellt. Es wird aufgezeigt, dass in den Ansätzen nicht nur die Genese von Normen und Praxen bei je unterschiedlichen sozialen Akteur:innen verortet wird, sondern auch deren (sozialwissenschaftliche) Bewertung. Dies geht seinerseits im Forschungsprozess mit unterschiedlichen Partizipationsmöglichkeiten derjenigen, deren Praxis Gegenstand der Forschung ist, einher.
Triterpenoid saponins from the fruit pulp of Tetrapleura tetraptera (Fabaceae)
Creators: name: Fru, G.
name: Khan, Serab
name: Kuete, Jenifer R. N.
name: Matieta, Valaire Y.
name: Ombito, Japheth. O.
name: Tamfu, Alfred. N.
name: Megaptche, Junior F.
name: Chongong, Melvis A.
name: Demissie, Taye B.
name: Kuete, Victor
name: Shaheen, Farzana
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Tetrapleura tetraptera fruit, used as spice in West Africa was studied chemically; five previously undescribed triterpenoid saponins 1–5 and four known compounds 6–9 were isolated from the n-Butanol fraction. The chemical structures of all nine isolates were determined by comprehensive analysis of HRMS, 1D & 2D NMR experiments and by comparison with data in the literature. All nine compounds were evaluated for antibacterial activity by the broth microdilution through the rapid p-iodonitrotetrazolium chloride (INT) colorimetric technique. The results showed that only compounds 5 (MIC = 64 µg/mL against P. aeruginosa and P. stuartii) and 8 (MIC = 64 µg/mL against E. coli) exhibited moderate antibacterial activity. The rest of the compounds displayed weak antibacterial activity against the tested organisms. Molecular docking studies was used to comprehend antibacterial activities.
Kulturräume als außerschulische Lernorte : Einsichten aus der Entwicklung einer Lehrpersonenfortbildung im Design-Thinking-Verfahren
Creators: name: Leuschen, Lara
name: Kaya, Tania
name: Emden, Markus
name: Hannich, Frank
Publisher: name: KM Kulturmanagement Network
Year: 2024
Subjects: Lehrperson
Ausserschulischer Unterricht
Design-Thinking
371: Schulen und schulische Tätigkeiten

description: Mit dem Ziel, eine bessere Verknüpfung des Klassenbesuchs mit dem Regelunterricht zu ermöglichen, hat das Swiss Science Center Technorama in Kooperation mit der Pädagogischen Hochschule Zürich (PH Zürich) im Rahmen eines MINT-Förderprogramms eine Lehrpersonenweiterbildung entwickelt. Um ein tiefgehendes Verständnis für die Bedürfnisse und Erwartungen der Teilnehmenden an außerschulisches Lernen und die Lehrpersonenweiterbildung zu erlangen, wurde der Entwicklungsprozess vom Institut für Marketing Management und dem Zentrum für Kulturmanagement der Zürcher Hochschule für Angewandte Wissenschaften (ZHAW) eng begleitet, wobei ein Design-Thinking-Ansatz verfolgt wurde.
Effects of omecamtiv mecarbil and mavacamten in isolated human atrium
Creators: name: Abella, Lina Maria Rayo
name: Höhm, Christian
name: Hofmann, Britt
name: Gergs, Ulrich
name: Neumann, Joachim
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Heart failure is a syndrome that can result from impaired heart muscle contractions like in dilative cardiomyopathy but also from hypertrophic obstructive cardiomyopathy (HOCOM). A pharmacological therapy might lie in Ca2+-sensitizing or Ca2+-desensitizing drugs, respectively. Such drugs are thought to be omecamtiv mecarbil (OME) and mavacamten (MYK-461), respectively. Their function in contracting human muscle is not fully understood and was the focus of the present study. OME from 1 nM to 10 µM cumulatively applied failed to raise force of contraction in human right atrial preparations strips (HAP) or mouse left atrial preparations (LA). However, OME prolonged time to peak tension and time of relaxation in HAP and LA but did not alter the beating rate in right atrial preparations from mice (RA). In contrast, MYK-461 (10 nM to 10 µM) reduced concentration- and time-dependently force of contraction in HAP and LA. MYK-461 (10 µM) did not affect the beating rate in RA. In summary, the present data failed to detect an increase in force of contraction for OME, in human and mouse atrium. In contrast, a Ca2+ desensitizer studied for comparison was able to reduce force of contraction in HAP and LA. We conclude that putative beneficial effects of OME in dilated cardiomyopathy cannot be explained by positive inotropic effects in the HAP, whereas beneficial functional effects of MYK-461 in HOCOM can be explained by negative inotropic effects in HAP.
Additional file 2 of Part II: understanding pain in pigs—pain assessment in pigs with spontaneously occurring diseases or injuries
Creators: name: Kschonek, Julia
name: Deters, Kathrin
name: Miller, Moana
name: Reinmold, Jennifer
name: Twele, Lara
name: Emmerich, Ilka
name: Kästner, Sabine
name: Kemper, Nicole
name: Kreienbrock, Lothar
name: Hennig-Pauka, Isabel
name: Wendt, Michael
name: Beilage, Elisabeth grosse
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 2
ESI: Revealing hidden patterns in binary rare-earth intermetallics RX through chemical intuition and interpretable machine learning
Creators: name: Gvozdetskyi, Volodymyr
name: Selvaratnam, Balaranjan
name: Oliynyk, Anton O.
name: Mar, Arthur
Publisher: name: figshare
Year: 2022
Subjects: subject: 30206 Solid State Chemistry
subject: FOS: Chemical sciences

description: Input and outputs for the machine learning and SISSO calculations performed for the project entitled "Revealing hidden patterns in binary rare-earth intermetallics RX through chemical intuition and interpretable machine learning".
 This zip file contains the Jupyter notebook files (and PDF snapshots) used for the ML models and the SISSO calculation files. 1. RX_Classification_final_v2 - Optimization of SVC, RF, and DT models. 2. RX_Data_for_Table_and_SI - Calculation of feature importance and average metrics for SVC, RF, and DT models. 3. SISSO_Regression - SISSO files for the regression to find the y axis expression. 4. SISSO_Classification - SISSO classification for the RX data set. 5. Figure_5_plot_data.csv - predicted class and probabilities by the ML models.
Neuroprotective potential of Alpinia calcarata and HPLC analysis of stigmasterol against cisplatin-induced neuropathy in rat model
Creators: name: Dhavale, Apurwa
name: M.G, Hariprasad
name: Chiprikar, Pallavi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Cisplatin is a chemotherapeutic agent known for causing severe peripheral neuropathy as a side effect, impacting patients’ quality of life by damaging nerve tissues. This study aims to explore the neuroprotective effects of the ethanolic extract of Alpinia calcarata Roscoe rhizome (EEACR) and stigmasterol identified by high-performance liquid chromatography (HPLC) in a rat model of cisplatin-induced neuropathy. Male Wistar rats were divided into control, cisplatin-induced neuropathic, and two intervention groups receiving different concentrations of EEACR (250 and 500 mg/kg). Neuropathy was induced with cisplatin administered intraperitoneally at a dose of 2 mg/kg per week for five weeks. The intervention groups were treated orally with EEACR daily during the induction period. Treatment with EEACR showed a significant attenuation of neurotoxicity as evidenced by behavioural improvements in mechanical allodynia, thermal hyperalgesia, and cold allodynia. HPLC analysis confirmed the presence of stigmasterol in EEACR, which may contribute to its therapeutic effects. Biochemical assessments revealed a significant decrease in oxidative stress markers and an increase in antioxidant enzyme activities, including superoxide dismutase, catalase, and glutathione peroxidase, in the nervous tissues of EEACR-treated rats. Histopathological examination indicated a reduction in nerve damage and enhanced preservation of myelin and axonal structures in the treatment groups. The findings from this study suggest that EEACR, enriched with stigmasterol, offers promising neuroprotective effects against cisplatin-induced neuropathy in rats.
Supplemental Material, Appendix_2 - The Children’s Social Comprehension Scale (CSCS): Construct validity of a new social intelligence measure for elementary school children
Creators: name: Knopp, Katarzyna A
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental Material, Appendix_2 for The Children’s Social Comprehension Scale (CSCS) by Katarzyna A Knopp in International Journal of Behavioral Development
Fluorinated linkers enable high-voltage pyrrolidinium-based dicationic ionic liquid electrolytes
Creators: name: Katcharava, Zviadi
name: Tirkalaee, Faranazh
name: Orlamünde, Torje
name: Kinkelin, Simon-Johannes
name: Busse, Karsten
name: Beiner, Mario
name: Marinow, Anja
name: Binder, Wolfgang H.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 540

description: Novel fluorinated, pyrrolidinium-based dicationic ionic liquids (FDILs) as high-performance electrolytes in energy storage devices have been prepared, displaying unprecedented electrochemical stabilities (up to 7 V); thermal stability (up to 370 °C) and ion transport (up to 1.45 mS cm−1). FDILs were designed with a fluorinated ether linker and paired with TFSI/FSI counterions. To comprehensively assess the impact of the fluorinated spacer on their electrochemical, thermal, and physico-chemical properties, a comparison with their non-fluorinated counterparts was conducted. With a specific focus on their application as electrolytes in next-generation high-voltage lithium-ion batteries, the impact of the Li-salt on the characteristics of dicationic ILs was systematically evaluated. The incorporation of a fluorinated linker demonstrates significantly superior properties compared to their non-fluorinated counterparts, presenting a promising alternative towards next-generation high-voltage energy storage systems.
การถ่ายทอดองค์ความรู้ภูมิปัญญาท้องถิ่นการทอเสื่อกก
Creators: name: สุกัญญา ดวงอุปมา; ภัทรพร ภาระนาค
Publisher: name: สมศักดิ์การพิมพ์
Year: 2556
Subjects: องค์ความรู้; ภูมิปัญญาท้องถิ่น; การทอเสื่อกก

description: วารสารการพัฒนาชุมชนและคุณภาพชีวิต, 1, 3
การจัดการความรู้บนฐานทุนชุมชนเพื่อการพัฒนา คุณภาพชีวิตอย่างยั่งยืน ในพื้นที่ลุ่มน้ำทะเลสาบสงขลา
Creators: name: ประมาณ เทพสงเคราะห์; จรินทร์ เทพสงเคราะห์; อดิศร ศักดิ์สูง; ศุภการ สิริไพศาล; พรศักดิ์ พรหมแก้ว; วรุตม์ นาที
Publisher: name: สมศักดิ์การพิมพ์
Year: 2556
Subjects: การจัดการความรู้; ทุนชุมชน; การพัฒนาคุณภาพชีวิต

description: วารสารการพัฒนาชุมชนและคุณภาพชีวิต, 1, 3
Wreck of the Clan Galbraith, July 1916
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 1916
Subjects: East Hampton
Shipwrecks
Boat & ship industry
Beaches
Ship accidents
Ships

description: This photograph shows the scene of the wreck of the Norwegian iron bark, Clan Galbraith, in July 1916. This ship beached near Flying Point in Water Mill and 22 members of the crew were saved. This ship was later sunk by a German Submarine in the English Channel in 1918.
การพัฒนาตู้อบแห้งและการรมควันกำมะถันผักตบชวาสำหรับ ชุมชนบ้านสาง ตำบลบ้านสาง อำเภอเมือง จังหวัดพะเยา
Creators: name: จรัญ คนแรง; อัญชณา อุประกูล
Publisher: name: สมศักดิ์การพิมพ์
Year: 2556
Subjects: ตู้อบแห้ง; การรมควันกำมะถัน; ผักตบชวา

description: วารสารการพัฒนาชุมชนและคุณภาพชีวิต, 1, 3
ALT (allogeneic limbal transplantation) : a new surgical technique for limbal stem cell deficiency
Creators: name: Viestenz, Anja
name: Kesper, Christiane
name: Hammer, Thomas
name: Heinzelmann, Joana
name: Foja, Sabine
name: Viestenz, Arne
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Purpose: Limbal stem cell deficiency (LSCD) is a rare but extremely relevant disease of the eye. LSCD patients often require a variety of surgical procedures, including keratoplasty in some cases. However, the outcome of these surgeries, including opacification and revascularization, is often frustrating due to LSCD relapse. Methods: We developed a new surgical technique for the treatment of LSCD in which partial allogenic limbal transplantation (ALT) is carried out as part of penetrating keratoplasty (PK). After the PK, 1–8 slices from the limbal tissue of the donor graft are prepared and placed under the double running sutures attaching the corneal graft. This procedure was performed on 14 patients with LSCD, caused by severe ocular burn in 5 cases and by infection in 9. Between one and eight limbal transplants were used depending on the extension of the LSCD. Results: All 14 patients showed stable or increased visual acuity after the ALT surgery compared to their preoperative visual acuity. All of the grafts were integrated into the superficial corneal layers without progression of corneal vascularization beyond the limbal grafts. The median follow-up period was 12 months on average. Conclusion: The ALT method seems to be a promising surgical procedure for the treatment of patients with LSCD. It can be properly carried out in the context of keratoplasty and does not require a separate donor tissue. The ALT grafts may offer the possibility of constructing a new limbal region, resulting in stable or even increased visual acuity and the absence of corneal vascularization.
Secondary prevention in diabetic and nondiabetic coronary heart disease patients : Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys
Creators: name: Ungethüm, Kathrin
name: Wiedmann, Silke
name: Frantz, Stefan
name: Noutsias, Michel
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Background: Patients with coronary heart disease (CHD) with and without diabetes mellitus have an increased risk of recurrent events requiring multifactorial secondary prevention of cardiovascular risk factors. We compared prevalences of cardiovascular risk factors and its determinants including lifestyle, pharmacotherapy and diabetes mellitus among patients with chronic CHD examined within the fourth and fifth EUROASPIRE surveys (EA-IV, 2012–13; and EA-V, 2016–17) in Germany. Methods: The EA initiative iteratively conducts European-wide multicenter surveys investigating the quality of secondary prevention in chronic CHD patients aged 18 to 79 years. The data collection in Germany was performed during a comprehensive baseline visit at study centers in Würzburg (EA-IV, EA-V), Halle (EA-V), and Tübingen (EA-V). Results: 384 EA-V participants (median age 69.0 years, 81.3% male) and 536 EA-IV participants (median age 68.7 years, 82.3% male) were examined. Comparing EA-IV and EA-V, no relevant differences in risk factor prevalence and lifestyle changes were observed with the exception of lower LDL cholesterol levels in EA-V. Prevalence of unrecognized diabetes was significantly lower in EA-V as compared to EA-IV (11.8% vs. 19.6%) while the proportion of prediabetes was similarly high in the remaining population (62.1% vs. 61.0%). Conclusion: Between 2012 and 2017, a modest decrease in LDL cholesterol levels was observed, while no differences in blood pressure control and body weight were apparent in chronic CHD patients in Germany. Although the prevalence of unrecognized diabetes decreased in the later study period, the proportion of normoglycemic patients was low. As pharmacotherapy appeared fairly well implemented, stronger efforts towards lifestyle interventions, mental health programs and cardiac rehabilitation might help to improve risk factor profiles in chronic CHD patients.