cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding
Creators: name: Heerde, Thomas
name: Rennegarbe, Matthies
name: Biedermann, Alexander
name: Savran, Dilan
name: Pfeiffer, Peter B.
name: Hitzenberger, Manuel
name: Baur, Julian
name: Puşcalău-Gîrţu, Ioana
name: Martini, Zacharias
name: Schwierz, Nadine
name: Haupt, Christian
name: Schmidt, Matthias
name: Fändrich, Marcus
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Cryoelectron microscopy
subject: Molecular conformation
subject: Protein aggregation
subject: DDC 540 / Chemistry & allied sciences
subject: DDC 570 / Life sciences
subject: Prions
subject: Prion

description: Several studies showed that seeding of solutions of monomeric fibril proteins with ex vivo amyloid fibrils accelerated the kinetics of fibril formation in vitro but did not necessarily replicate the seed structure. In this research we use cryo-electron microscopy and other methods to analyze the ability of serum amyloid A (SAA)1.1-derived amyloid fibrils, purified from systemic AA amyloidosis tissue, to seed solutions of recombinant SAA1.1 protein. We show that 98% of the seeded fibrils remodel the full fibril structure of the main ex vivo fibril morphology, which we used for seeding, while they are notably different from unseeded in vitro fibrils. The seeded fibrils show a similar proteinase K resistance as ex vivo fibrils and are substantially more stable to proteolytic digestion than unseeded in vitro fibrils. Our data support the view that the fibril morphology contributes to determining proteolytic stability and that pathogenic amyloid fibrils arise from proteolytic selection.
HATS-4b: a dense hot-Jupiter transiting a super metal-rich G star
Creators: name: Jordan, Andres
name: Brahm, Rafael
name: Bakos, G. A.
name: Bayliss, D.
name: Penev, K.
name: Hartman, J. D.
name: Zhou, G.
name: Mancini, L.
name: Mohler-Fischer, M.
name: Ciceri, S.
name: Sato, B.
name: Csubry, Z.
name: Rabus, M.
name: Suc, V.
name: Espinoza, N.
name: Bhatti, W.
name: Borro, M. de Val
name: Buchhave, L.
name: Csak, B.
name: Henning, T.
name: Schmidt, B.
name: Tan, T. G.
name: Noyes, R. W.
name: Beky, B.
name: Butler, R. P.
name: Shectman, S.
name: Crane, J.
name: Thompson, I.
name: Williams, Andrew
name: Martin, R.
name: Contreras, C.
name: Lazar, J.
name: Papp, I.
name: Sari, P.
Publisher: name: Swinburne
Year: 2024

description: We report the discovery by the HATSouth survey of HATS-4b, an extrasolar planet transiting a V = 13.46 mag G star. HATS-4b has a period of P ≈ 2.5167 days, mass of Mp ≈ 1.32 M Jup, radius of Rp ≈ 1.02 R Jup, and density of ρ p = 1.55 ± 0.16 g cm-3 ≈1.24 ρJup. The host star has a mass of 1.00 M ☉, a radius of 0.92 R ☉, and a very high metallicity [Fe/H]=0.43 ± 0.08. HATS-4b is among the densest known planets with masses between 1 and 2 M J and is thus likely to have a significant content of heavy elements of the order of 75 M ⊕. In this paper we present the data reduction, radial velocity measurements, and stellar classification techniques adopted by the HATSouth survey for the CORALIE spectrograph. We also detail a technique for simultaneously estimating vsin i and macroturbulence using high resolution spectra.
Le Sénat et l'influence américaine sur le syndicalisme canadien : étude d'un débat politique, 1903-1910.
Creators: name: Marion, Bruno.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: History, Canadian.

description: En 1903, 1907, 1909 et 1910, des projets de loi antisyndicaux sont déposés coup sur coup au Sénat. Ces bills auraient bien pu freiner l'évolution du syndicalisme canadien, qui est à cette époque à un tournant de son histoire. Menés par Lougheed, McMullen et Belcourt, certains sénateurs s'inquiètent de «l'influence étrangère» sur les sections locales canadiennes des syndicats internationaux. Aucun des projets de loi n'est adopté par le Parlement; mais le fait que la plus haute institution canadienne se penche sur la question mérite une attention particulière. Par contre, l'historiographie ne s'attarde guère sur ce débat, l'effleurant seulement à quelques reprises. Ce débat mérite pourtant une analyse en profondeur, puisque les constatations que l'on y fait sont révélatrices et démontrent son importance. Avec la reprise économique au tournant du siècle, le nombre d'organisations ouvrières augmente à un rythme effarant. La croissance du nombre des syndicats (particulièrement celui des organisations internationales) est phénoménale, ce qui entraîne le nombre de grèves à un sommet jusqu'alors inégalé. Certaines grèves particulièrement violentes, s'attirent alors les foudres de l'élite politique qui accusent des «agitateurs» américains de venir créer le trouble entre les travailleurs canadiens et leurs employeurs. (Abstract shortened by UMI.)
title: Essays on Sustainable Finance and Regulatory Risk
Creators: name: Müller, Lukas
Publisher: name: UNSPECIFIED
Year: 2024

description: Natural experiments have a long tradition in empirical corporate finance. Event study methodology is an incumbent approach for measuring the economic impact of an event on shareholder wealth. Within this context, this dissertation covers two main subject areas. The first part offers a methodological contribution to fundamental research in the field of corporate bonds. In fixed-income research, event study methodology lags far behind event studies in the field of equity, and existing approaches are insufficiently validated. In the first article, we replicate results from the previous literature and test the methodology for robustness to event-induced variance and illiquidity. We conclude that existing methods for analysing the impact on bondholder wealth are intractable and that researchers should carefully consider sample characteristics, liquidity, and the presence of event-induced variance. The second part of this dissertation is devoted to the application of event study methodology in equity markets to test existing theoretical frameworks with regard to political and regulatory risk and uncertainty. The second and third articles focus specifically on the carbon risk hypothesis and examine whether carbon emissions are priced in by investors. We show that market reactions to regulatory announcements are driven significantly by greenhouse gas emissions. The results provide short-term evidence supporting the carbon risk hypothesis. In the fourth article, we analyse the market impact of populist success in national elections. We show that the increase in OHLC volatility in the run-up to an election is a robust proxy for the sensitivity of a stock to the election outcome. On the one hand, this dissertation thus advances research in the field of corporate bonds, and on the other hand, it contributes to the verification of existing theoretical models on the influence of regulatory and political risks and uncertainties on shareholder wealth.
Supplementary document for Label-free identification of human coronary atherosclerotic plaque based on three-dimensional quantitative assessment of multiphoton microscopy images - 5092329.pdf
Creators: name: Zhang, Rongli
name: Xu, Zhongbiao
name: Hao, Junhai
name: Yu, Jia
name: liu, Zhiyi
name: Chen, Wanwen
name: Zhou, Jiahui
name: Li, Hui
name: Lin, Zhanyi
name: Zheng, Wei
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Fig.S1 and Fig.S2
L'ordine della solidarietà. Rapporto di Léon Bourgeois al Congresso d'Educazione Sociale nel 1900
Creators: name: Bourgeois, Leon
Publisher: name: Alma Mater Studiorum, University of Bologna
Year: 2010

description: L'ordine della solidarietà. Rapporto di Léon Bourgeois al Congresso d'Educazione Sociale nel 1900
"Les règles de la folie" ou sur l'introduction du syndrome prémenstruel dans les cours canadiennes de justice.
Creators: name: Harvey, Manon.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Women's Studies.

description: Traînant les vestiges du passé, notre société actuelle est de fait marquée du sexisme lequel est repérable dans tourtes ses structures et ses stratifications, y compris l'appareil judiciaire. Sous ce prisme, nous avons voulu vérifier in globo si l'introduction du SPM en cour, que ce soit à titre de défense ou qu'il soit utilisé contre la femme en situation de demanderesse/défenderesse, pouvait s'inscrire dans ces pratiques d'oppression contre les femmes. De quelles représentations sociales des femmes et de leur cté participe cette agence de contrôle social? Pour éclairer cette zone d'ombre, il fallait nécessairement mettre en lumière ce que la reconnaissance du syndrome prémenstruel (SPM) par les tribunaux signifiait et impliquait autant pour les femmes directement impliquées dans le processus judiciaire que pour celles en général. De ces considérations, il s'agissait enfin de se positionner par rapport à la pertinence du SPM dans le champs de la transgression et de son usage en cour sous quelque forme que ce soit. À cette fin, nous nous sommes servi/e/s de 6 transcriptions judiciaires, relevant des instances criminelle et civile, à l'intérieur desquelles nous avons effectué une analyse documentaire. (Abstract shortened by UMI.)
Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells
Creators: name: Anbalagan, Durkeshwari
name: Yap, Gracemary
name: Yuan, Yi
name: Pandey, Vijay K.
name: Lau, Wai Hoe
name: Arora, Suruchi
name: Bist, Pradeep
name: Wong, Justin S. B.
name: Sethi, Gautam
name: Nissom, Peter M.
name: Lobie, Peter E.
name: Lim, Lina H. K.
Publisher: name: Swinburne
Year: 2024

description: Annexin 1 (ANXA1) is an endogenous anti-inflammatory protein implicated in cancer. ANXA1 was previously shown to be regulated by hsa-miR-196a. However, whether ANXA1 itself regulates microRNA (miR) expression is unknown. Therefore, we investigated the regulation of miR by ANXA1 in MCF7 breast cancer cells. MCF7-EV (Empty vector) and MCF7-V5 (ANXA1-V5 expressing cells) were subjected to a miR microarray. Microarray analysis revealed a number of miRNAs which were dysregulated in MCF7-V5 cells. 2 novel miRNAs (miR562 and miR26b*) were validated, cloned and functionally characterized. As ANXA1 constitutively activates NF-κB activity to modulate breast cancer metastasis, we found that miR26b* and miR562 directly targeted the canonical NF-κB pathway by targeting the 3′ UTR and inhibiting expression of Rel A (p65) and NF-κB1 (p105) respectively. MiR562 inhibited wound healing, which was reversed when ANXA1 was overexpressed. Overexpression of either miR562 or miR26b* in MCF-7 cells enhanced endothelial tube formation when cocultured with human umbilical cord endothelial cells while conversely, treatment of MCF7 cells with either anti-miR562 or anti-miR26b* inhibited endothelial tube formation after co-culture. Further analysis of miR562 revealed that miR562-transfected cell conditioned media enhances endothelial cell tube formation, indicating that miR562 increased angiogenic secreted factors from MCF-7 breast tumor cells. TNFα was increased upon overexpression of miR562, which was reversed when ANXA1 was co-transfected In conclusion, this data suggests that ANXA1-regulated miR26b* and miR562 may play a role in wound healing and tumor-induced endothelial cell tube formation by targeting NF-κB expression and point towards a potential therapeutic target for breast cancer.
Benthic macroinvertebrate response to water quality in three rivers of Eastern Ontario.
Creators: name: Dean, Stuart L.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Biology, Ecology.

description: The benthic macroinvertebrate response to water quality changes was examined in riffle zones of three Eastern Ontario Rivers (Ottawa River, Rideau River and Jock River) during the spring and summer of 1995 and 1996. Water quality gradients were detected within the rivers but these were weakly correlated to invertebrate benthos structure making it impossible to predict one from the other. However, the observed differences in water quality among sites and rivers, although significant, may not provide a large enough water quality gradient to observe a strong signal with the invertebrate data. A principal component analysis on the invertebrate densities revealed that invertebrate variability was greater between seasons than between years. May--June samples tended to have higher variability than July--August samples. These results support a standardized approach to the macroinvertebrate sampling period from year to year and the need to sample during a less variable time of the year such as late summer or early fall. Some of the inherent problems with benthic invertebrate indices are examined and the appropriateness of a coarse taxonomic level are discussed. In general, I found no evidence of strong impacts of water quality on the benthos structure of the three rivers. However, at certain locations where water quality parameters were unusually high particularly compared to the guideline, we observed an increase in invertebrate abundance. This study does provide a reference point for each of our large rivers, from which we can compare to future monitoring work.
Expiratory peak flow and minute ventilation are significantly increased at high altitude versus simulated altitude in normobaria
Creators: name: Netzer, Nikolaus C.
name: Rausch, Linda K.
name: Frieß, Matthias
name: Strohl, Kingman P.
name: Schilz, Robert
name: Decker, Michael
name: Pramsohler, Stephan
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: spiroergometry
subject: air density
subject: normobaria
subject: hypobaria
subject: ventilation
subject: DDC 610 / Medicine & health
subject: Acclimatization; Pysiology
subject: Hypoxia; Physiopathology
subject: Exercise
subject: Altitude
subject: Pulmonary ventilation
subject: Spirometry
subject: Hypoxie
subject: Höhe
subject: Spiroergometrie

description: Simulated altitude (normobaric hypoxia, NH) is used to study physiologic hypoxia responses of altitude. However, several publications show differences in physiological responses between NH and hypobaric conditions at altitude (hypobaric hypoxia, HH). The causality for these differences is controversially discussed. One theory is that the lower air density and environmental pressure in HH compared to NH lead to lower alveolar pressure and therefore lower oxygen diffusion in the lung. We hypothesized that, if this theory is correct, due to physical laws (Hagen-Poiseuille, Boyle), resistance respectively air compression (Boyle) at expiration should be lower, expiratory flow higher, and therefore peak flow and maximum expiratory flow (MEF) 75–50 increased in hypobaric hypoxia (HH) vs. normobaric hypoxia (NH). To prove the hypothesis of differences in respiratory flow as a result of lower alveolar pressure between HH and NH, we performed spirography in NH at different simulated altitudes and the corresponding altitudes in HH. In a cross over study, 6 healthy subjects (2 f/4 m, 28.3 ± 8.2 years, BMI: 23.2 ± 1.9) performed spirography as part of spiroergometry in a normobaric hypoxic room at a simulated altitude of 2800 m and after a seven-hour hike on a treadmill (average incline 14%, average walking speed 1.6 km/h) to the simulated summit of Mauna Kea at 4200 m. After a two-month washout, we repeated the spirometry in HH on the start and top of the Mauna Kea hiking trail, HI/USA. Comparison of NH (simulated 4200 m) and HH at 4200 m resulted in increased pulmonary ventilation during exercise (VE) (11.5%, p < 0.01), breathing-frequency (7.8%, p < 0.01), peak expiratory flow PEF (13.4%, p = 0.028), and MEF50 (15.9%, p = 0.028) in HH compared to NH, whereas VO2max decreased by 2%. At 2800 m, differences were only trendy, and at no altitude were differences in volume parameters. Spirography expresses higher mid expiratory flows and peak flows in HH vs. NH. This supports the theory of lower alveolar and small airway pressure due to a lower air density resulting in a lower resistance.
Supplementary document for PHz-scale nonlinear photoconductive sampling in air - 5092368.pdf
Creators: name: Zimin, Dmitry
name: Weidman, Matthew
name: Schoetz, Johannes
name: Kling, Matthias
name: Yakovlev, Vladislav
name: Krausz, Ferenc
name: Karpowicz, Nicholas
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental information
Translating the Buffyverse: Examining French fan response to "Buffy contre les vampires"
Creators: name: Alnwick, Marie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Literature, Comparative.
subject: Language, General.

description: Fictional texts represent a particular challenge for translators due to their use of expressive language. The translation of audiovisual texts in particular is complicated by various institutional and technical constraints. As such, assessing the quality of translated televisual fiction is a complex undertaking that requires an approach more flexible than that prescribed by proponents of textual-linguistic models. This thesis looks at translation quality from another angle, that of audience reception. As a case study, this thesis investigates the reception of the French dubbed translation of Buffy the Vampire Slayer, a popular American television show characterized by its frequent use of illocutionary elements, including wordplay, neologisms and cultural references. One interpretive community's response to the French dubbed translation is examined through the document analysis of a French chat room thread dedicated to the dubbed version of the show. In order to check the legitimacy of fans' claims, a translated episode of Buff the Vampire Slayer is assessed, with posters' comments informing the evaluation criteria. In particular, the target text is evaluated according to its treatment of illocutionary strategies. The results of the document analysis and the translation evaluation are compared to give a multidimensional perspective on the quality of the target text. The evaluation highlights the prevailing tendency of the target text to omit illocutionary elements in favour of neutral paraphrase, and the document analysis suggests that this tendency may in part account for the chat viewers' largely negative response to Buffy the Vampire Slayer's French dubbed translation.
Arecibo pulsar survey using ALFA II: the young, highly relativistic binary pulsar J1906+0746
Creators: name: Lorimer, Duncan R.
name: Stairs, Ingrid H.
name: Freire, Paulo C.
name: Cordes, James M.
name: Camilo, Fernando
name: Faulkner, Andrew J.
name: Lyne, Andrew G.
name: Nice, David J.
name: Ransom, Scott M.
name: Arzoumanian, Zaven
name: Manchester, Richard N.
name: Champion, David J.
name: Van Leeuwen, Joeri
name: McLaughlin, Maura A.
name: Ramachandran, Ramesh
name: Hessels, Jason W.
name: Vlemmings, Wouter
name: Deshpande, Avinash A.
name: Bhat, N. D. R.
name: Chatterjee, Soumya
name: Han, Jinlin Lin
name: Gaensler, Bryan M.
name: Kasian, Laura
name: Deneva, Julia S.
name: Reid, Beth
name: Lazio, T. Joseph
name: Kaspi, Victoria M.
name: Crawford, Fronefield
name: Lommen, Andrea N.
name: Backer, Donald C.
name: Kramer, Michael
name: Stappers, Benjamin W.
name: Hobbs, George B.
name: Possenti, Andrea
name: D'Amico, Nichi
name: Burgay, Marta
Publisher: name: Swinburne
Year: 2024

description: Abstract not available.
Supplementary document for PHz-scale nonlinear photoconductive sampling in air - 5092368.pdf
Creators: name: Zimin, Dmitry
name: Weidman, Matthew
name: Schoetz, Johannes
name: Kling, Matthias
name: Yakovlev, Vladislav
name: Krausz, Ferenc
name: Karpowicz, Nicholas
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplemental information
An evaluation study of various excitation signals for electrical impedance spectroscopy
Creators: name: Rajabzadeh, Mahdi
name: Ungethuem, Jonathan
name: Mandry, Holger
name: Schilpp, Carolin
name: Wittekindt, Oliver
name: Ortmanns, Maurits
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Single-bit sigma-delta modulator
subject: Electrical impedance spectroscopy
subject: Signal type
subject: DDC 610 / Medicine & health
subject: DDC 620 / Engineering & allied operations
subject: Multichannel communication
subject: Modulators
subject: Driver
subject: Impedance spectroscopy
subject: Tissues
subject: Biomedical engineering
subject: Electric impedance
subject: Spectrum analysis
subject: Lung
subject: Mehrkanalübertragung
subject: Modulator
subject: Sigma-Delta-Wandler
subject: Gewebe
subject: Lunge
subject: Spektroskopie
subject: Biomedizinische Technik

description: Electrical Impedance Spectroscopy (EIS) is a popular method for investigating tissue properties. Implementing the signal generator for EIS measurements with a suitable excitation signal type is thereby one of the two system components. The choice of the excitation signal defines the measurement speed, signal-to-noise ratio (SNR), total area and power consumption of the system, and many more properties. Signal types such as analog single-tone, analog multi-tone, linear feedback shift registers (LFSR), and single-tone Sigma Delta Modulated (SDM) are proposed in the state of the art. In this work an EIS setup is implemented and successfully tested with all the mentioned signal types to evaluate their properties on impedance models as well as in vitro cell layers. It is proposed to combine the SDM with the multi-tone excitation signal yielding a very versatile excitation generator. Multi-tone SDM are as fast as analog multitones, while benefiting from a binary output and thus less system complexity. The implemented EIS setup is used to perform EIS measurement for biological samples. The results show a very good matching with the reference for all the excitation signals.
"Organizzare la semplicità" per una democrazia matura. Roberto Ruffilli e le riforme istituzionali
Creators: name: Antonetti, Nicola
Publisher: name: Alma Mater Studiorum, University of Bologna
Year: 2010

description: "Organizzare la semplicità" per una democrazia matura. Roberto Ruffilli e le riforme istituzionali
Adventures in data literacy: When the gap you were trying to identify turns out to be a chasm
Creators: name: Miller, Meg
name: O'Hanlon, Grace
Publisher: name: Zenodo
Year: 2024

description: In an era where post-secondary students are seen as digital natives and data storytelling is becoming an expected part of scholarly discourse, this paper synthesizes insights from multiple surveys. This research was conducted in 2020 and 2022 with participants from programs across the University of Manitoba (UM) to illuminate the landscape of data literacy. This paper will not only delineate the current landscape of data literacy at UM (a Canadian public research university of around 30,000 students) but also explore challenges and potential pathways for improvement. The authors hope this paper can serve as a foundational resource guiding those who work in data services towards a data-literate future.
Opening Open Science Conference 2021 by Klaus Tochtermann
Creators: name: Tochtermann, Klaus
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: Other

description: 8th international conference of the Leibniz Research Alliance Open Science., , ; doi:10.5446/53439
description: The Open Science Conference 2021 is the 8th international conference of the Leibniz Research Alliance Open Science. The annual conference is dedicated to the Open Science movement and provides a unique forum for researchers, librarians, practitioners, infrastructure providers, policy makers, and other important stakeholders to discuss the latest and future developments in Open Science.
Supplementary document for Modified distributed Bragg reflector for protecting organic light-emitting diode displays against ultraviolet light - 5092759.pdf
Creators: name: Lin, Kai-Chen
name: Lee, Wei-Kai
name: Wang, Bo-Kai
name: Lin, Yu-Hsing
name: Chen, Hsien-Hung
name: Song, Yi-Hwa
name: Huang, Yu-Hsin
name: Shih, Li-Wei
name: Wu, Chung-Chih
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplementary materials
EDF consensus on CAN bus access in dynamic real-time applications
Creators: name: Livani, Mohammad Ali
name: Kaiser, Jörg
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Computer algorithms
subject: Real-time data processing
subject: CAN-Bus
subject: Echtzeitverarbeitung

description: N/A
Jahresbericht der Universität Ulm 2011
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 050 / General serial publications
subject: Research; Ulm
subject: Universities; Germany; Ulm
subject: Forschungsbericht
subject: Universität Ulm

description: Jahresbericht der Universität Ulm 2011 in deutscher und englischer Sprache
Correction : Tugault-Lafleur C.N. and Black J.L. “Differences in the Quantity and Types of Foods and Beverages Consumed by Canadians between 2004 and 2015” Nutrients 2019, 11, 526
Creators: name: Tugault-Lafleur, Claire N.
name: Black, Jennifer L.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: We would like to submit the following corrections to our recently published paper [...]
A comparison of TCP congestion control algorithms in 10G networks
Creators: name: Lukaseder, Thomas
name: Bradatsch, Leonard
name: Erb, Benjamin
name: Van Der Heijden, Rens W.
name: Kargl, Frank
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: TCP
subject: Congestion control
subject: DDC 000 / Computer science, information & general works
subject: DDC 004 / Data processing & computer science
subject: TCP/IP (Computer network protocol)

description: The increasing availability of 10G Ethernet network capabilities challenges existing transport layer protocols. As 10G connections gain momentum outside of backbone networks, the choice of appropriate TCP congestion control algorithms becomes even more relevant for networked applications running in environments such as data centers. Therefore, we provide an extensive overview of relevant TCP congestion control algorithms for high-speed environments leveraging 10G. We analyzed and evaluated six TCP variants using a physical network testbed, with a focus on the effects of propagation delay and significant drop rates. The results indicate that of the algorithms compared, BIC is most suitable when no legacy variant is present, CUBIC is suggested otherwise.
Closing Open Science Conference 2021 by Klaus Tochtermann
Creators: name: Tochtermann, Klaus
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: Other

description: doi:10.5446/53437
description: The Open Science Conference 2021 is the 8th international conference of the Leibniz Research Alliance Open Science. The annual conference is dedicated to the Open Science movement and provides a unique forum for researchers, librarians, practitioners, infrastructure providers, policy makers, and other important stakeholders to discuss the latest and future developments in Open Science.
A Correlation of High Speed Drag Data
Creators: name: Hensel, Rudolph William
name: Heimer, Harry James
Publisher: name: California Institute of Technology
Year: 1944
Subjects: Aeronautics
(Aeronautical Engineering)

description: In fulfillment of the purpose of this investigation, a method of estimating the drag of an airplane at high Mach numbers has been derived. Two sets of curves, one for airplanes having conventional wing sections and the other for those having low drag sections, were drawn to show the percentage increase in total drag with the ratio of free stream Mach number to critical Mach number of the wing.
A method for computation of the blocking correction is presented and applied, resulting in good agreement between the wind tunnel and flight tests. Wind tunnel data corrected for the blocking effect were chiefly used to deduce the conclusions, but they were supplemented by all the flight test results available.
Potentials and Limitations of Different Requirements (Offsetting) in Bilateral and Global Carbon Pricing Systems
Creators: name: Wang-Helmreich, Hanna
name: Kreibich, Nico
name: Kurdziel, Marie-Jeanne
Publisher: name: My University
Year: 2017
Subjects: subject: Klimaänderung
subject: Klimapolitik
subject: Kohlenstoffmarkt
subject: Chile
subject: Südafrika
subject: climate change
subject: climate policy
subject: carbon market
subject: carbon pricing
subject: carbon tax
subject: carbon offsetting
subject: linking effect
subject: transfer of mitigation outcomes
subject: Co-benefits
subject: co-costs
subject: international climate finance
subject: partnership for market readiness
subject: PMR
subject: Mexico
subject: South Africa
subject: emissions trading
subject: Climate | Energy

description: This report explores the introduction of carbon taxes with a national offset component and their interactions with other policy areas, and makes recommendations on this topic. In this task, the study focuses on the approaches Chile, Mexico and South Africa have chosen for elaborating their carbon taxes. The study identifies the objectives the three countries pursue by introducing these new systems as well as the requirements they establish for the use of offsets. Furthermore, it analyses the interaction between the use of offsets and other policy areas, in particular on co-benefits, co-costs and long-term emissions mitigation trajectories. Quelle:http://www.umweltbundesamt.de/
description: This report explores the introduction of carbon taxes with a national offset component and their interactions with other policy areas, and makes recommendations on this topic. In this task, the study focuses on the approaches Chile, Mexico and South Africa have chosen for elaborating their carbon taxes. The study identifies the objectives the three countries pursue by introducing these new systems as well as the requirements they establish for the use of offsets. Furthermore, it analyses the interaction between the use of offsets and other policy areas, in particular on co-benefits, co-costs and long-term emissions mitigation trajectories.
The landscape of particle production: results from PHOBOS
Creators: name: Steinberg, P.
name: Back, B. B.
name: Baker, M. D.
name: Ballintijn, M.
name: Barton, D. S.
name: Becker, B.
name: Betts, R. R.
name: Bickley, A. A.
name: Bindel, R.
name: Budzanowski, A.
name: Busza, W.
name: Carroll, A.
name: Decowski, M. P.
name: Garcia, E.
name: Gburek, T.
name: George, N.
name: Gulbrandsen, K.
name: Gushue, S.
name: Halliwell, C.
name: Hamblen, J.
name: Harrington, A. S.
name: Heintzelman, G. A.
name: Henderson, C.
name: Hofman, D. J.
name: Hollis, R. S.
name: Holynski, R.
name: Holzman, B.
name: Iordanova, A.
name: Johnson, E.
name: Kane, J. L.
name: Katzy, J.
name: Khan, N.
name: Kucewicz, W.
name: Kulinich, P.
name: Kuo, C. M.
name: Lee, J. W.
name: Lin, W. T.
name: Manly, S.
name: McLeod, D.
name: Mignerey, A. C.
name: Nouicer, R.
name: Olszewski, A.
name: Pak, R.
name: Park, I. C.
name: Pernegger, H.
name: Reed, C.
name: Remsberg, L. P.
name: Reuter, M.
name: Roland, C.
name: Roland, G.
name: Rosenberg, L.
name: Sagerer, J.
name: Sarin, P.
name: Sawicki, P.
name: Sedykh, I.
name: Skulski, W.
name: Smith, C. E.
name: Stephans, G. S. F.
name: Sukhanov, A.
name: Tang, J. L.
name: Tonjes, M. B.
name: Trzupek, A.
name: Vale, C.
name: Van Nieuwenhuizen, G. J.
name: Verdier, R.
name: Veres, G. I.
name: Wolfs, F. L. H.
name: Wosiek, B.
name: Wozniak, K.
name: Wuosmaa, A. H.
name: Wyslouch, B.
name: Zhang, J.
Publisher: name: Swinburne
Year: 2024

description: Recent results from the PHOBOS experiment at RHIC are presented, both from Au+Au collisions from the 2001 run and p+p and d+Au collisions from 2003. The centrality dependence of the total charged-particle multiplicity in p+p and d+Au shows features, such as Npart scaling and limiting fragmentation, similar to p+A collisions at lower energies. Multiparticle physics in Au+Au is found to be local in (pseudo)rapidity, both when observed by HBT correlations and by forward–backward pseudorapidity correlations. The shape of elliptic flow in Au+Au, measured over the full range of pseudorapidity, appears to have a very weak centrality dependence. Identified particle ratios in d+Au reactions show little difference between the shape of proton and anti-proton spectra, while the absolute yields show an approximate mT scaling. Finally, results on RdAu as a function of pseudorapidity show that this ratio decreases monotonically with η, even between 0.2 < η < 1.4.
The Federal Open Science Repository of Canada: A key destination on Canada’s Roadmap to Open Science
Creators: name: Venne, Renee
Publisher: name: Forschungzentrum Jülich
Year: 2022
Subjects: Information Science

description: doi:10.5446/58282
description: Until now, a large part of Government of Canada scientists and researchers have not had the infrastructure to make their scientific publications openly available. This presentation outlines how we are addressing this gap, through the development of the Federal Open Science Repository of Canada (FOSRC), a shared repository to make federally funded scientific outputs accessible to all.
The Cytotoxic Effects of Methylmercury on Cardiomyocytes: A Possible Implication for Heart Diseases?
Creators: name: Truong, Jocelyn
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Environmental Toxicology
Methylmercury
H9C2
AC16
Cardiovascular Disease
Environmental Health

description: Methylmercury (MeHg) is known predominantly as a neurotoxicant, however emerging experimental and epidemiological evidence has shown associations between MeHg exposure and the potential for increased risks of cardiovascular diseases. This thesis investigated the in vitro cytotoxic effects of MeHg in two cardiomyocyte cell lines, H9C2 rat neonatal cell line and AC16 adult human cell line. We observed significant increases in cell death at concentrations from 1 – 10 µM. ROS production and intracellular calcium concentrations increased dose-dependantly with MeHgCl exposure. Furthermore, while assessing mitochondrial function, a decline in maximal respiration at 1 µM was seen. However, these observations may in turn be a direct consequence of decreased cell numbers following exposures. Additionally, this study highlighted the differences in cellular bioenergetics which may impact how certain cells respond to contaminant stressors. The distribution of MeHg and total Hg in rat heart tissues was also examined and we observed increasing concentrations of MeHg in high and low dosed rat groups as compared to the vehicle controls. No difference was observed in Hg levels between the normal and high fat and sugar diet groups. The urinary isoprostane levels, which are indicative of systemic oxidative stress, showed significant increases in lean rats exposed to the high dose treatment. It was also observed that a high fat and sugar diet in lean and obese rats can contribute to increasing oxidative stress regardless of the level of contaminants they were dosed with. This thesis demonstrated several in vitro effects of MeHg on heart cells as well as determine the distribution of Hg levels in heart tissues and oxidative stress markers from an in vivo study.
Derivation of a new mathematical framework for transmission system augmentation using von Stackelberg game
Creators: name: Hesamzadeh, M. R.
name: Hosseinzadeh, N.
name: Wolfs, P. J.
Publisher: name: Swinburne
Year: 2024

description: The market-based augmentation of the high voltage transmission systems as a legacy of the previous regulated regimes has been a challenging issue for the central transmission entities. The economic assessment framework for transmission upgrades or expansion projects, considering the interaction of the central transmission entity (CTE) with the electricity market management (MMC) company both as independent players needs to be addressed appropriately at least in the National Electricity Market, Australia. To assist in bridging this gap, this paper introduces a novel metric, namely, the L-Shape Area, for the economic assessment of the transmission expansion options. The proposed methodology employs a von Stackelberg game for the interaction modelling of the central transmission entity and the market management company. The upper subproblem minimises the objective of the CTE as the leader player and the lower subproblem solves the security-constrained economic dispatch as the follower subproblem. The bi-level programming problem has been solved by applying the Kuhn-Tucker optimality conditions to the follower subproblem and the use of a gradient search method to solve the resultant single level non-linear programming problem.
Supplementary document for Modified distributed Bragg reflector for protecting organic light-emitting diode displays against ultraviolet light - 5092759.pdf
Creators: name: Lin, Kai-Chen
name: Lee, Wei-Kai
name: Wang, Bo-Kai
name: Lin, Yu-Hsing
name: Chen, Hsien-Hung
name: Song, Yi-Hwa
name: Huang, Yu-Hsin
name: Shih, Li-Wei
name: Wu, Chung-Chih
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: supplementary materials
The promotion of impressive in-session client changes: A discovery-oriented study of psychotherapeutic change.
Creators: name: Hamblin Lazaro, Margaret.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Psychology, Clinical.

description: The purpose of this thesis is to provide a preliminary examination of the findings of a long term, continuous, research project on psychotherapy. Data have been collected for approximately five years. The plan is for further data to be collected for another three to four years or more. Sufficient data have been collected to enable a substantial look at the findings so far. This is the purpose of this thesis. The research is directed toward answering four questions: (1) What were the categories or kinds of impressive in-session client changes judged to be found in the pool of 40 instances? The research found 8 categories of impressive in-session changes. (2) Were the categories of impressive in-session changes found to occur in an identifiable sequence or sequences? The research found that the impressive in-session client changes occurred in two somewhat overlapping but substantially different patterns or sequences within sessions. (3) For each of the 8 categories of impressive in-session changes, what did the therapist, or therapist and client, do that were judged as enabling the in-session impressive changes to occur? For each of the 8 categories of impressive in-session changes, the research was able to identify and to specify ways that the therapists, and therapists and clients, were judged as enabling the occurrence of the impressive in-session changes. (4) For each of the 8 categories of in-session changes, what did the therapists do following the occurrence of the impressive in-session client change? What the therapists did following the occurrence of the impressive in-session client change was incorporated into the judges' instructions as the identification and specification of ways the therapists used the occurrences. For each of the 8 categories of impressive in-session client changes, the research was able to identify and to specify ways the therapists used the occurrences of the impressive in-session client changes.
La Maddalena nell'arte. Conferenza tenuta al Circolo Filologico di Napoli li 22 maggio 1884
Creators: name: Minghetti, Marco
Publisher: name: Alma Mater Studiorum, University of Bologna
Year: 2010

description: La Maddalena nell'arte. Conferenza tenuta al Circolo Filologico di Napoli li 22 maggio 1884
title: Evaluation and Analysis of the Education Financing and Management Reform Project in the Republic of Armenia
Creators: name: Rostomyan, Ara
Publisher: name: University of Massachusetts Amherst
Year: 2002
Subjects: subject: Education
subject: Educational Assessment, Evaluation, and Research

description: This project provides an evaluation and analysis of the Education Financing and Management Reform Project. Among the few larger-scope reform projects designed for more expansive changes in the education system of Armenia, Education Financing and Management Reform Project is the most Important, in terms of both its financial aspects and the scale of targeted changes. The project provides an evaluation and analysis of the Education Financing Management Reform Project from two points of view: the choice of textbook and publication/provision and achieving successful decentralization of schools. It will also try to find out to what extent the proposed changes match the general development of the country, thus evaluating the chances of success also from this aspect. With a rather pessimistic attitude regarding the effectiveness of the project, the two project questions will be put in the negative: (i) why is this project irrelevant for achieving improvement of the quality of the general education system in Armenia? and (ii) why this project cannot achieve its concrete goals - improved textbook publication and provision and successful school decentralization? The project comprises of two chapters, each of which covers one of the two questions stated above. The first chapter provides an analysis of the textbook and decentralization components as tools for quality improvement in the general education system. The second chapter analyzes the actual chances of the project to achieve its concrete objectives - successful textbook publication and provision, and school decentralization. For avoiding complication and setting a logical line of analysis, each of the chapters is divided into several sections (some of these having also subsections).
The Open Science Publishing Flood and Collaborative Authoring
Creators: name: Worthington, Simon
name: Speicher, Daniel
name: Roio, Denis
name: Hülk, Ludwig
name: Murray-Rust, Peter
Publisher: name: Forschungzentrum Jülich
Year: 2019
Subjects: Information Technology

description: , , ; doi:10.5446/36525
description: Currently there is a deluge of ‘off-piste’ collaborative authoring going on in Open Science, the adoption of: software versioning systems like GitHub for writing; simulations and code in platforms like Jupyter; or in ‘real time’ web authoring ‘operational transformation algorithm’ based software like Etherpad. Yes, the ‘digital plumbing’ of this publishing flood is just not in place. How do we ID these documents, reuse them for example? These questions have been asked and answered before, but are outside the fast moving, forward looking tech world. As an example, Ted Nelson coined the term ‘transclusion’ (Nelson 1987) back in the ‘80s. Transclusion is a step on from the ‘hyperlink’, another Nelson term, where not just the link of a target is included in a document but instead the whole content (AKA live linked embedding). Currently if you want to link and include another document fragment in your document with persistence, it’s unlikely to work. The panelists will explore how this exciting field can better support research.
Supplementary document for Cooling and Diffusion Characteristics of Hot Carrier in the Monolayer WS₂ - 5093307.pdf
Creators: name: Wang, Wenyan
name: Sui, Ning
name: Kang, zhihui
name: Zhou, Qiang
name: Li, Li
name: Chi, Xiaochun
name: Zhang, Hanzhuang
name: He, Xing
name: Zhao, Bing
name: Wang, Yinghui
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement material
Les effets de la stimulation électrique intracérébrale de régions renforçantes en interaction avec la stimulation intracérébrale de régions aversives.
Creators: name: Diotte, Magali.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Biology, Neuroscience.

description: Les propriétés analgésiques de la stimulation électrique ont été explorées en utilisant divers paradigmes de recherche. Plusieurs études portant sur le sujet ont utilisé des stimuli aversifs externes pour évaluer les propriétés antinociceptives d'une région cérébrale renforçante alors que peu d'entre elles ont évalué l'interaction d'un stimuli aversif interne (site cérébral nociceptif) avec l'une ou l'autre de ces régions. Le principal objectif des études constituant ma thèse était d'analyser les particularités antinociceptives de certaines régions renforçantes du cerveau lorsqu'elles sont mises en interaction avec un site aversif. L'une des études effectuées a examiné la stimulation électrique renforçante de l'hypothalamus latéral (HL) en interaction avec le noyau gigantocellulaire réticulaire (NGR); une autre analysait l'influence du raphé dorsal (DR) sur l'aversion du NGR; la dernière explorait la possible réplication de l'effet antinociceptif du RD sur une autre structure aversive, le tegmentum dorsal (DTg). Dans chacune de ces recherches, deux instruments de mesure, la latence d'échappement des régions aversives et la courbe de fonction taux-fréquence (un seul renforcement et combinaison des deux types de renforcement) ont servi à évaluer l'interaction produite. Les deux structures renforçantes mises en relation avec le NGR ayant démontré des propriétés antinociceptives, nous avons pu confirmer que le renforcement intracérébral joue un rôle primordial dans la disparition de l'aversion. Nos études ont également révélé que le RD associe de façon plus expéditive les pulsions renforçantes et aversives (NGR) que le HL mais, qu'une fois l'antinociception installée dans l'un et l'autre sites, elle ne présente aucune différence d'intensité ou de durée (permanente et irréversible). Les particularités intrinsèques du DTg, autre site aversif étudié en association avec le RD, nous ont cependant empêchées de généraliser le phénomène antinociceptif à d'autres structures régissant l'aversion car, dès le début des tests, la stimulation seule du DTg réussissait à faire disparaître la nocicéption. En bref, ce qui se dégage des études constituant cet ouvrage peut être exprimé par les quatre assertions suivantes: (1) l'HL et le RD, deux régions renforçantes, ont la capacité de modifier la nociception émanant du NGR; (2) les propriétées anti-aversives de l'HL et celles du RD n'ont pas la même rapidité d'apparition; (3) l'effet antinociceptif du NGR est irréversible, et, finalement, (4) le DTg semble posséder une action auto-analgésique. (Abstract shortened by UMI.)
Book review: 'Psychoanalysis: Its image and its public', by Serge Moscovici
Creators: name: Wagoner, Brady
name: Oldmeadow, Julian
Publisher: name: Swinburne
Year: 2024

description: Brady Wagoner and Julian A. Oldmeadow review the book 'Psychoanalysis: Its image and its public', by Serge Moscovici (translator D. Macey), published by Polity Press, Cambridge, 2007.
Development and Characterization of the Solvent-Assisted Active Loading Technology (SALT) for Liposomal Loading of Poorly Water-Soluble Compounds
Creators: name: Pauli, Griffin
name: Tang, Wei-Lun
name: Li, Shyh-Dar
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: A large proportion of pharmaceutical compounds exhibit poor water solubility, impacting their delivery. These compounds can be passively encapsulated in the lipid bilayer of liposomes to improve their water solubility, but the loading capacity and stability are poor, leading to burst drug leakage. The solvent-assisted active loading technology (SALT) was developed to promote active loading of poorly soluble drugs in the liposomal core to improve the encapsulation efficiency and formulation stability. By adding a small volume (~5 vol%) of a water miscible solvent to the liposomal loading mixture, we achieved complete, rapid loading of a range of poorly soluble compounds and attained a high drug-to-lipid ratio with stable drug retention. This led to improvements in the circulation half-life, tolerability, and efficacy profiles. In this mini-review, we summarize our results from three studies demonstrating that SALT is a robust and versatile platform to improve active loading of poorly water-soluble compounds. We have validated SALT as a tool for improving drug solubility, liposomal loading efficiency and retention, stability, palatability, and pharmacokinetics (PK), while retaining the ability of the compounds to exert pharmacological effects.