cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Platyrrhinus aurarius Handley and Ferris 1972
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Phyllostomidae
Platyrrhinus
Platyrrhinus aurarius

description: Platyrrhinus aurarius Handley and Ferris 1972
Platyrrhinus aurarius Handley and Ferris 1972, Proc. Biol. Soc. Wash., 84: 522.
Type Locality: Venezuela, Bolivar, 85 km SSE El Dorado, 1,000 m.
Vernacular Names: Eldorado Broad-nosed Bat.
Distribution: S Venezuela, Guyana, Surinam. Specimens previously reported from Colombia appear to have been misidentified.
Conservation: IUCN 2003 and IUCN / SSC Action Plan (2001) – Lower Risk (nt).
Discussion: May be a synonym of dorsalis; see Jones and Carter (1976).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Chiroptera - Family Phyllostomidae, pp. 395-426 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 1, Baltimore :The Johns Hopkins University Press on page 422, DOI: 10.5281/zenodo.7316519
Keeping Up with the KEMs: Stronger Security Notions for KEMs.
Creators: name: Cremers, Cas
name: Dax, Alexander
name: Medinger, Niklas
Publisher: name: CISPA
Year: 2024

description: Key Encapsulation Mechanisms (KEMs) are a critical building block for hybrid encryption and modern security protocols, notably in the post-quantum setting. Given the asymmetric public key of a recipient, the primitive establishes a shared secret key between sender and recipient. In recent years, a large number of abstract designs and concrete implementations of KEMs have been proposed, e.g., in the context of the NIST process for post-quantum primitives.

In this work, we (i) establish stronger security notions for KEMs, and (ii) develop a symbolic analysis method to analyze security protocols that use KEMs. First, we generalize existing security notions for KEMs in the computational setting, introduce several stronger security notions, and prove their relations. Our new properties formalize in which sense outputs of the KEM uniquely determine, i.e., bind, other values. Our new binding properties can be used, e.g., to prove the absence of attacks that were not captured by prior security notions, such as re-encapsulation attacks.

Second, we develop a family of fine-grained symbolic models that correspond to our hierarchy of computational security notions, and are suitable for the automated analysis of KEM-based security protocols. We encode our models as a library in the framework of the Tamarin prover. Given a KEM-based protocol, our approach can automatically derive the minimal binding properties required from the KEM; or, if also given a concrete KEM, can analyze if the protocols meets its security goals. In case studies, Tamarin automatically discovers, e.g., that the key exchange protocol proposed in the original Kyber paper requires stronger properties from the KEM than were proven in the paper.
Platyrrhinus brachycephalus Rouk and Carter 1972
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Phyllostomidae
Platyrrhinus
Platyrrhinus brachycephalus

description: Platyrrhinus brachycephalus Rouk and Carter 1972
Platyrrhinus brachycephalus Rouk and Carter 1972, Occas. Pap. Mus. Texas Tech Univ., 1: 1.
Type Locality: Peru, Huanuco, 3 mi. (5 km) S Tingo Maria, 2,400 ft. (732 m).
Vernacular Names: Short-headed Broad-nosed Bat.
Synonyms: Platyrrhinus latus Handley and Ferris 1972; Platyrrhinus saccharus Handley and Ferris 1972.
Distribution: N Brazil; Colombia to Guianas; Ecuador; Peru; Bolivia.
Conservation: IUCN 2003 and IUCN / SSC Action Plan (2001) – Lower Risk (lc).
Discussion: Includes latus; see Jones and Carter (1976). May not be distinct from helleri; see Alberico (1990), but also see Anderson (1996).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Chiroptera - Family Phyllostomidae, pp. 395-426 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 1, Baltimore :The Johns Hopkins University Press on page 422, DOI: 10.5281/zenodo.7316519
Platyrrhinus chocoensis Alberico and Velasco 1991
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Phyllostomidae
Platyrrhinus
Platyrrhinus chocoensis

description: Platyrrhinus chocoensis Alberico and Velasco 1991
Platyrrhinus chocoensis Alberico and Velasco 1991, Bonn. Zool. Beitr., Vol. 42: 238.
Type Locality: Colombia, Departamento del Chocó, 12 km W Istmina (by road), Quebrada El Platinero, 5°00'N, 76°45'W, 100 m.
Vernacular Names: Choco Broad-nosed Bat.
Distribution: W Colombia, lowlands between the Western Cordillera of the Andes and the Pacific coast.
Conservation: IUCN 2003 and IUCN / SSC Action Plan (2001) – Vulnerable.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Chiroptera - Family Phyllostomidae, pp. 395-426 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 1, Baltimore :The Johns Hopkins University Press on page 423, DOI: 10.5281/zenodo.7316519
Platyrrhinus dorsalis Thomas 1900
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Phyllostomidae
Platyrrhinus
Platyrrhinus dorsalis

description: Platyrrhinus dorsalis Thomas 1900
Platyrrhinus dorsalis Thomas 1900, Ann. Mag. Nat. Hist., ser. 7, 5: 269.
Type Locality: Ecuador, Paramba, 1,100 m.
Vernacular Names: Thomas's Broad-nosed Bat.
Distribution: Panama to Peru and Bolivia.
Conservation: IUCN 2003 and IUCN / SSC Action Plan (2001) – Lower Risk (lc).
Discussion: Although the named forms umbratus, oratus, and aquilus were regarded as synonyms of dorsalis by Carter and Rouk (1973), these apparently represent a distinct species for which the oldest name is umbratus; see Handley (1976).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Chiroptera - Family Phyllostomidae, pp. 395-426 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 1, Baltimore :The Johns Hopkins University Press on page 423, DOI: 10.5281/zenodo.7316519
title: Publishing 1922: popular writing, modernism, and the reader
Creators: name: Bruce, Benjamin
Publisher: name: University of Reading
Year: 2024

description: This thesis is a literary study of popular writing (novels and poetry) in the year 1922 to 
enable a fuller characterisation of these twelve months by recovering a lost literary 
history. Offering a new and very different view of this year the research undertakes an 
historicist analysis of some of the year’s bestselling poetry and prose, the wider culture, 
and the mainstream publishing industry which capitalised on the continuing trend 
towards mass, popular publishing. Based on original primary research in the Archive of 
British Publishing and Printing at the University of Reading, the Macmillan Archive at 
the British Library, and the Hodder and Stoughton Limited files at the London 
Metropolitan Archives, the thesis explores profit and loss ledgers, stock books, 
advertising material, reviews, and correspondence often previously unconsidered. The 
research includes a case study of the publication of two Chatto and Windus titles by 
Aldous Huxley and Beverley Nichols. It considers the crime writing of Victor Bridges, 
Agatha Christie, ‘Sapper’, J. S. Fletcher and Cyril Alington in the emerging Golden Age. 
After debating the romantic fiction of Ethel M. Dell, Elinor Glyn and Ruby M. Ayres, a 
final chapter discusses the popular poetry of Thomas Hardy, Edmund Blunden and A. 
E. Housman in the aftermath of the Great War. This thesis argues that it is necessary to 
re-frame ideas about 1922, which has consistently been misrepresented in earlier studies 
that have privileged the work of James Joyce, T. S. Eliot, Virginia Woolf and others. As 
such this is a study centrally concerned with cultural issues of value and the interactions 
between social context and the publications of the day. This work recuperates some of 
the important novels and poems otherwise lost to history, those texts that intrigued and 
excited readers, whilst acknowledging that modernist writing itself is often thematically 
contiguous with the popular literature it eschewed. This research offers a valuable and 
countervailing narrative to that offered by previous literary history.
Nature-based Solutions using Ponds and Pondscapes : 16 leaflets (English and local languages) presenting the PONDERFUL Demonstration Sites (DEMO-sites).
Creators: name: Oertli, Beat
name: Sordet, Adrienne
name: Bartrons, Mireia
name: Beklioglu, Meryem
name: Benejam, Lluís
name: Biggs, Jeremy
name: Boissezon, Aurélie
name: Davidson, Thomas Alexander
name: Hornung, Jules
name: Lago, Manuel
name: Lemmens, Pieter
name: Meerhoff, Mariana
name: Mehner, Thomas
name: Nicolet, Pascale
name: Quintana, Xavier
name: Rasmussen, Marzenna
name: Robin, Joël
name: Williams, Penny
name: Brucet, Sandra
Publisher: name: Zenodo
Year: 2024
Subjects: Pondscape
Wetlands
Ponds
Biodiversity
Nature-based solutions
Ecosystem services
Nature's contribution to people
Best practices

description: This publication brings together 16 leaflets (in English and in local Languages) developed for the DEMO-sites of the EU H2020 PONDERFUL project (2020-2024). These summary “leaflet” cover each of the 16 demonstration pondscapes located across various EU countries, as well as Turkey and Uruguay. 

The main objective of the DEMO-SITES leaflets is to (i) present a selection of evidence-based success stories identified as part of the implementation of Nature-based Solutions (NbS) for addressing societal challenges in those pondscapes (such as climate change and biodiversity loss), and (ii) promote the implementation of the best practice measures illustrated in the DEMO-sites leaflets to other pondscapes.

The success stories are assessed in terms of indicators of Nature Contribution to People (NCP) and by a cost-benefit analysis. The leaflets were primarily written and designed for practitioners and other stakeholders, including NGOs, involved in land use planning and nature conservation management, but also for private citizens with an interest in issues linked with climate change and its impact on NCPs. The information provided in the leaflets is intentionally simplified to avoid scientific jargon and make the key results and messages from the PONDERFUL project accessible to a broad audience.
Nature-based Solutions using Ponds and Pondscapes : 16 leaflets (English and local languages) presenting the PONDERFUL Demonstration Sites (DEMO-sites).
Creators: name: Oertli, Beat
name: Sordet, Adrienne
name: Bartrons, Mireia
name: Beklioglu, Meryem
name: Benejam, Lluís
name: Biggs, Jeremy
name: Boissezon, Aurélie
name: Hornung, Jules
name: Lago, Manuel
name: Lemmens, Pieter
name: Meerhoff, Mariana
name: Mehner, Thomas
name: Nicolet, Pascale
name: Quintana, Xavier
name: Rasmussen, Marzenna
name: Robin, Joël
name: Williams, Penny
name: Brucet, Sandra
Publisher: name: Zenodo
Year: 2024
Subjects: Pondscape
Wetlands
Ponds
Biodiversity
Nature-based solutions
Ecosystem services
Nature's contribution to people
Best practices

description: This publication brings together 16 leaflets (in English and in local Languages) developed for the DEMO-sites of the EU H2020 PONDERFUL project (2020-2024). These summary “leaflet” cover each of the 16 demonstration pondscapes located across various EU countries, as well as Turkey and Uruguay. 

The main objective of the DEMO-SITES leaflets is to (i) present a selection of evidence-based success stories identified as part of the implementation of Nature-based Solutions (NbS) for addressing societal challenges in those pondscapes (such as climate change and biodiversity loss), and (ii) promote the implementation of the best practice measures illustrated in the DEMO-sites leaflets to other pondscapes.

The success stories are assessed in terms of indicators of Nature Contribution to People (NCP) and by a cost-benefit analysis. The leaflets were primarily written and designed for practitioners and other stakeholders, including NGOs, involved in land use planning and nature conservation management, but also for private citizens with an interest in issues linked with climate change and its impact on NCPs. The information provided in the leaflets is intentionally simplified to avoid scientific jargon and make the key results and messages from the PONDERFUL project accessible to a broad audience.
Molecular Engineering of Indacenodifuran-Based Non-Fullerene Acceptors for Efficient Organic Solar Cells
Creators: name: Hussain, Muzammil
name: Adnan, Muhammad
name: Hussain, Riaz
name: Irshad, Zobia
name: Haidry, Azhar Ali
name: Chaudhry, Aijaz Rasool
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Space Science
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology

description: Energy-efficient non-fullerene acceptors attracting great attention for developing efficient organic solar cells (OSCs). Though many materials have been developed to improve the optical and optoelectronic characteristics of OSCs, the search continues to strengthen this field further. Therefore, herein, we designed an environmentally-benign indacenodifuran-based electron acceptor molecules (MH1-MH8) by substituting various end-capped electron-withdrawing moieties (COOH, SO3H, NO2, and CN). The open-circuit-voltages, binding energy, transition energy, transition density analysis, and electron and hole reorganization energies for MH1–MH8 were computed for these materials. These designed materials MH1-MH8 have better photovoltaic, photophysical, and electrical properties than R due to their narrower bandgap (1.91 eV), higher absorption (725.56 and 785.46 nm in gas and chloroform), low-mobility of electrons (0.0033) and holes (0.0019), and lower binding energy of 0.20 eV). We have also performed a charge transfer study by establishing a donor:acceptor complex MH2:PTB7-TH, showing a great charge transformation at the donor:acceptor interface. Thus, the designed compounds (MH1-MH8) with excellent optoelectronic properties could be considered a promising and environmentally friendly option to create compelling organic solar cells.
Photophysical and Physiochemical Study of New Pyrenyl Chalcone Derivatives as Sensitizers for Organic Solar Cells
Creators: name: Rajasagaran, Rineswary
name: Nizar, Siti Nabilla Aliya Mohd
name: Alsaee, Saleh K.
name: Rosli, Mohd Mustaqim
name: Samsuri, Siti Azrah Mohamad
name: Ibrahim, Abdul Razak
name: Arshad, Suhana
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Three pyrenyl chalcone derivatives namely, PCH1, PCH2, and PCH3 were synthesized by utilizing the Claisen-Schmidt condensation technique. Compound PCH1 was successfully recrystallized via the slow evaporation technique. To determine and refine the crystal structure, the single crystal is subjected to X-ray diffraction (XRD) analysis. Crystal packing reveals that intermolecular C-H···O interactions bind molecules in compound PCH1 in a head-to-head arrangement. Intramolecular charge transfer (ICT) between molecules has improved as a result of the compound’s C-H···O contacts. The compounds were then characterized using UV-Vis spectroscopy where all compounds have an energy gap that is within the low range, ranging from 2.89 to 2.94 nm. Furthermore, the HOMO-LUMO energy levels of the pyrenyl chalcones were examined by conducting CV analysis. The energy levels of the compounds essentially lie between the conduction band of TiO2 and the redox potential (I−/I3−) of the electrolyte. FESEM and EDX analyses were utilized in solar cell performance investigations to examine the surface topography and elemental mapping of the pyrenyl compound on the TiO2 layer, correspondingly. Compound PCH2 emerges as the most effective dye-sensitizer in DSSC applications due to the anchoring of strong substituent groups in the compound, even though all three compounds demonstrated suitability as dye-sensitizer materials.
Functionalized 2-Amino-4H-1-Benzopyran-4-yl Phosphonate Scaffolds: Synthesis, Anticancer Evaluation and Computational Studies
Creators: name: Sudileti, Murali
name: Gundluru, Mohan
name: Konidala, Kranthi Kumar
name: Chintha, Venkataramaiah
name: Nagaripati, Saichaithanya
name: Nemallapudi, Bakthavatchala Reddy
name: Neeraja, Pabbaraju
name: Zyryanov, Grigory V.
name: Cirandur, Suresh Reddy
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Prostate, breast, and lung cancers are various human cancers that have been associated with SRC kinase mutations. Therefore, the development of potent and selective SRC kinase inhibitors is an exciting area of interest for researchers. In this study, we synthesized a series of 2-amino-4H-1-benzopyran-4-yl phosphonate derivatives through a one-pot reaction involving appropriately substituted salicylaldehydes, malononitrile, and diethyl phosphite, with meglumine as the catalyst. We conducted in vitro screening of these compounds for their anticancer activity against human prostate cancer (DU-145), breast cancer (MCF-7), and lung cancer (A549) cell lines using the MTT assay. Notably, compounds 4a, 4j, 4k, and 4l exhibited promising anticancer activity. Molecular docking studies of these compounds supported their potential as therapeutic agents for SRC kinase inhibition. Specifically, compounds 4a, 4b, 4c, 4d, and 4e demonstrated strong ΔG binding affinities ranging from −7.9 to −7.4 kcal/mol. These findings suggest that these molecules hold promise for cancer treatment.
THE STUDY OF REPTILES IN CENTRAL ASIA AND THE MORPHOLOGICAL ANALYSIS OF SPECIES (BASED ON SCIENTIFIC COLLECTIONS)
Creators: name: Karimjonov, Kamronbek
Publisher: name: Zenodo
Year: 2024

description: This study focuses on analyzing the reptile species found in Central Asia, their morphological characteristics, and the history of their research. Utilizing scientific collections, morphological differences within reptile populations were identified, and their adaptations to different habitats were evaluated. Geometric morphometric methods were employed, providing insights into species variation through statistical and mathematical shape analysis. The findings offer essential data for reptile conservation and scientific classification. Additionally, this study contributes to addressing urgent issues in ecological monitoring and biodiversity preservation.
Investigating frictional contact behavior for soft material robot simulations
Creators: name: Berthold, Rebecca
name: Burgner-Kahrs, Jessica
name: Wangenheim, Matthias
name: Kahms, Stephanie
Publisher: name: Dordrecht [u.a.] : Springer Science + Business Media B.V
Year: 2023
Subjects: subject: Contact modeling
subject: Elastomers
subject: Friction
subject: Friction measurement
subject: Soft robotics
subject: Dewey Decimal Classification::600 | Technik

description: The ability to interact safely with the environment is known as one of the major advantages of soft robots (SRs). Due to their low material stiffness, these continuously deformable robots offer inherent flexibility. These advantages make them suitable for application that involve human-robot collaboration in industrial settings as well as medical application such as minimally invasive surgery. To date only few research groups have analyzed the contact and frictional behavior of soft robots. In fact, the contact behavior is often oversimplified or neglected. Motivated by the idea to bridge this gap, this work presents measurements and the resulting coefficient of friction (COF) for silicone rubbers that are widely used in the field of SRs and different contact partners which depend on contact pressure and ambient temperature. From these measurements, a more representative contact model is established and used to more accurately simulate soft material robots’ frictional contact behavior. Moreover the influence of friction and therefore the need to implement frictional behavior is demonstrated for a typical application of a SR.
Design, Synthesis, Drug-Likeness, anti-Inflammatory, Antimicrobial Activity, and Molecular Docking Studies of Pyrimidine Analogs
Creators: name: N, Jeelan Basha
name: KT, Akshay
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mental Health

description: Grounded on medicinal significances of pyrimidines, herein we are reporting initially the design and synthesis of 1-(2-benzylthiopyrimidin-4-yl)-benzimidazol-2-thioacetic acid/thioacetate 2(a, b), 1-(2-benzylthiopyrimidin-4-yl)-3,5 diaryl-2-pyrazoline (3) and 1-(2-benzylthiopyrimidin-4-yl)-3,5-dimethylpyrazole (4). In silico screening such as molecular docking studies of these compounds with inflammation-causing enzyme cyclooxagenase-2 (COX-2) suggests that only 2a has shown a strong affinity for the COX-2 (−9.0 kcal/mol) and forms three hydrogen bonds with active amino acid residues in comparison with standard anti-inflammatory drugs celecoxib (-8.8 kcal/mol) and indomethacin (-7.7 kcal/mol). However, in vitro, anti-inflammatory activity reveals that IC50 of compound 2a was 3.5 μM compared to celecoxib with IC50 of 0.65 μM. Also, 2a has displayed comparable activity of standard antibacterial drug gentamycin against E. coli with MIC 6.5 μM. Furthermore, the drug-likeness of potent compounds was studied using Swiss ADME and Mol inspiration software. All the compounds showed optimum drug-likeness without violating Lipinski’s rule of five. With our best observation and based on comparative SAR studies of these analogs with celecoxib and indomethacin, we conclude that compound 2a could develop as a therapeutically potent anti-inflammatory agent.
The MPIfR-MeerKAT Galactic Plane Survey: II. The eccentric double neutron star system PSR J1208a-5936 and a neutron star merger rate update
Creators: name: Colom I Bernadich, M.
name: Balakrishnan, V.
name: Barr, E.
name: Berezina, M.
name: Burgay, M.
name: Buchner, S.
name: Champion, D.J.
name: Chen, W.
name: Desvignes, G.
name: Freire, P.C.C.
name: Grunthal, K.
name: Kramer, M.
name: Men, Y.
name: Padmanabh, P.V.
name: Parthasarathy, A.
name: Pillay, D.
name: Rammala, I.
name: Sengupta, S.
name: Venkatraman, Krishnan V.
Publisher: name: Les Ulis : EDP Sciences
Year: 2023
Subjects: subject: Binaries: close
subject: Celestial mechanics
subject: Ephemerides
subject: Gravitational waves
subject: Stars: fundamental parameters
subject: Stars: neutron
subject: Dewey Decimal Classification::500 | Naturwissenschaften::520 | Astronomie, Kartographie

description: The MPIfR-MeerKAT Galactic Plane survey at L-band (MMGPS-L) is the most sensitive pulsar survey in the Southern Hemisphere, providing 78 discoveries in an area of 900 sq. deg. Here, we present a follow-up study of one of these new discoveries, PSR J1208a-5936, a 28.71-ms recycled pulsar in a double neutron star system with an orbital period of Pb=0.632 days and an eccentricity of e=0.348, merging within the Hubble time. Through timing of almost one year of observations, we detected the relativistic advance of periastron ( Ì = 0.918(1) deg yra-1), resulting in a total system mass of Mt=2.586(5) M·. We also achieved low-significance constraints on the amplitude of the Einstein delay and Shapiro delay, in turn yielding constraints on the pulsar mass (Mp = 1.26a-0.25+0.13 M·), the companion mass (Mc = 1.32a-0.13+0.25 M·), and the inclination angle (i=57 ± 12). This system is highly eccentric compared to other Galactic field double neutron stars with similar periods, possibly hinting at a larger-than-usual supernova kick during the formation of the second-born neutron star. The binary will merge within 7.2(2) Gyr due to the emission of gravitational waves, making it a progenitor of the neutron star merger events seen by ground-based gravitational wave observatories. With the improved sensitivity of the MMGPS-L, we updated the Milky Way neutron star merger rate to be RMWnew = 25a-9+19 Myra-1 within 90% credible intervals, which is lower than previous studies based on known Galactic binaries owing to the lack of further detections despite the highly sensitive nature of the survey. This implies a local cosmic neutron star merger rate of Rlocalnew = 293a-103+222 Gpca-3 yra-1, which is consistent with LIGO and Virgo O3 observations. With this, we also predict the observation of 10a-4+8 neutron star merger events during the LIGO-Virgo-KAGRA O4 run. We predict the uncertainties on the component masses and the inclination angle will be reduced to 5- 10a-3 M· and 0.4 after two decades of timing, and that in at least a decade from now the detection of b and the sky proper motion will serve to make an independent constraint of the distance to the system.
Status, Source, and Risk Assessment of Heavy Metal(Loid)s and Polycyclic Aromatic Hydrocarbons (PAHs) in the Street Dust of Ilam, Iran
Creators: name: Ehtemae, Neda
name: Ghanavati, Navid
name: Nazarpour, Ahad
name: Babaeinejad, Teimour
name: Watts, Michael James
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: A total of 25 Ilam street dust specimens were sampled to investigate the possible ecological and health risks of heavy metal(loid)s and polycyclic aromatic hydrocarbons (PAHs). We found that the average concentrations of heavy metal(loid)s, namely Pb, Zn, Cu, Cr, Cd, Ni, V, and As, were 52, 213, 63, 46, 0.4, 44, 31, and 5 mg/kg, respectively. The average concentration of all heavy metal(loid)s except for Cr and V was several times higher than the baseline values. We evaluated Zn and Pb in the region using the average enrichment factor (EF) and pollution index (PI); the Nemerow integrated pollution index (NIPI) indicated that 76% of the samples had high degrees of pollution. According to principal component analysis (PCA), three principle components are involved in the heavy metal(loid) pollution of Ilam street dust. For example, the pollution sources of Cu, Cr, Cd, and Ni likely originated from anthropogenetic origins, including traffic, tire depreciation, and gasoline use. The sources of Pb and Zn were other anthropogenic activities, such as metal corroding and the combustion of garbage and gases from industries, while V and As were probably from natural sources. The range of sum over 11 PAHs was 167–11,497 μg/kg with a mean of 2242 μg/kg. The concentration of low molecular weight (LMW) PAHs averaged 1471 μg/kg, accounting for 66% of the total PAHs; their sources were mainly associated with combustion and pyrogenic emissions. The PCA also revealed that PAHs mainly originated from burning fossil fuels. The values of RQ∑PAHs (MPCs) and RQ∑PAHs (NCs) were respectively >1 and ≥800, indicating a high ecosystem risk for PAHs. Mean values for RQ∑PAHs (MPCs) and RQ∑PAHs (NCs) were 4 and 1021, respectively, implying that Ilam street dust poses a relatively high ecosystem risk of PAHs. Street dust PAHs’ toxic equivalency quotient (TEQ) varied from 26 to 199 μg/kg. The total cancer risk was 3.92 × 10−4 and 4.06 × 10−4 for adults and children, respectively, indicating that the potential for cancer risk is very high through dust dermal contact and ingestion.
Multi-step Synthesis of Novel Pyrazole Derivatives as Anticancer Agents
Creators: name: Vyas, Amita K.
name: Lunagariya, Kaushik S.
name: Khunt, Ranjan C.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: The attractiveness of pyrazole and its derivatives is increasing because of their numerous potential pharmacological applications. A novel series of pyrazole hybrid compounds (6A–6L) has been synthesized, and all the intermediates and the final products were characterized by 1H NMR, IR, and mass spectrometry. Pyrazole derivatives were screened for their anticancer activity against the NCI-60 cell lines, and grouped into nine different subpanels. In-vitro anticancer studies of the targeted compounds showed that the compounds 6C, 6D, 6F, 6I, and 6J showed potent anticancer activity against renal cancer, ovarian cancer, melanoma, and leukemia cancer.
Potentially Bioactive Novel Isophthalic Acid Based Azo Molecules: Synthesis, Characterization, Quantum Chemical Calculations, ADMET Properties, Molecular Docking and Molecular Dynamics Simulations
Creators: name: Ulutürk, Mehmet
name: Atay, Çiğdem Karabacak
name: Dede, Bülent
name: Tilki, Tahir
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: We report here the synthesis of the two novel molecules 5-((5-hexyl-2,4-dihydroxyphenyl)diazenyl)isophthalic acid (3a) and 5-((5-ethyl-2,4-dihydroxyphenyl)diazenyl)isophthalic acid (3b). The structures of the 3a and 3b were confirmed by using 1H-NMR,13C-NMR, FT-IR, UV-vis, and HR-ESI-MS techniques. The optimized molecular geometry, vibrational frequency,1H- and 13C-NMR spectra calculations were performed using the DFT/B3LYP method with a 6-311G(d,p) basis set. The frontier molecular orbitals and electronic transition wavelengths were calculated at the level of TD-DFT/CAM-B3LYP/6-311G(d,p). The experimental data obtained for the synthesized molecules were in good agreement with the theoretical ones. The calculated HOMO-LUMO band gap revealed that 3a has a softer character and may be more reactive in chemical reactions. Important ADMET parameters of the compounds were also calculated, and the obtained physicochemical, pharmacokinetic, drug similarity, and toxicity data were at the desired level for a candidate bioactive compound. In order to examine the potential anticancer or antibacterial properties of newly synthesized azo molecules, molecular docking studies were performed using four different proteins. The best interaction was determined to be between 3a and VEGFR2 (PDB ID: 2XIR) with a binding energy of 9.0 kcal/mol. Moreover, a 50 ns MD simulation study for 3a-2XIR revealed that the complex maintained both its structural integrity and molecular interactions throughout the simulation.
Frequency dependent amplitude response of different couplant materials for mounting piezoelectric sensors
Creators: name: Xu, Ronghua
name: Beltrán-Gutiérrez, Raúl Enrique
name: Käding, Max
name: Lange, Alexander
name: Marx, Steffen
name: Ostermann, Jörn
Publisher: name: Amsterdam [u.a.] : Elsevier Science
Year: 2023
Subjects: subject: Acoustic emission (AE)
subject: Couplant material
subject: Laser Doppler vibrometer
subject: Non-destructive testing (NDT)
subject: Signal transmission
subject: Dewey Decimal Classification::600 | Technik

description: Non-destructive testing techniques, such as ultrasonic testing and acoustic emission analysis, commonly employ piezoelectric sensors for monitoring and detecting defects in structures. The quality of data acquired using these sensors is highly dependent on the coupling layer between the transducer and the structure's surface. In this context, this study compares the signal response of four different couplant materials, namely acrylic adhesive pads, honey, vaseline, and hot glue, applied to a steel surface. For this purpose, experiments were conducted using a laser Doppler vibrometer and acoustic emission analysis to investigate the signal transmission of the couplant materials and their impact on the signal response of a coupled piezoelectric sensor VS30-V. The repeatability of the experiments was statistically analyzed. The findings indicate that acoustic emission measurements with acrylic adhesive pads exhibited the lowest relative standard deviation of 11.4%, followed by honey (13.2%), hot glue (21.9%), and vaseline (32.1%). The investigated couplant materials exhibited different effects on the signal response of the piezoelectric sensor. Specifically, acrylic adhesive pads and hot glue demonstrated more reliable signal transmission in the frequency range of 50 kHz to 65 kHz. In contrast, honey and vaseline had better performance within the frequency range of 65 kHz and 80 kHz. Considering the frequency-dependent characteristics of signal transmission and the ease of application, acrylic adhesive pads and honey are considered the preferred couplant materials for the frequency ranges of 50 kHz to 65 kHz and 65 kHz to 80 kHz, respectively.
Spectroscopic Characterization, Quantum Chemical, Molecular Docking, Antibacterial and Anticancer Studies on Ethyl Coumarin-3-Carboxylate: an Antibacterial and Lung Cancer Agent
Creators: name: Mohan, Surya S.
name: M.R., Meera
name: A., Rathika
name: R., Premkumar
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: The detailed theoretical and experimental (FT-IR, FT-Raman, UV-visible) spectroscopy analyses of the Ethyl Coumarin-3-Carboxylate (ECC) molecule were carried out. The ECC compound’s pharmacological properties were also investigated, utilizing antibacterial and anticancer activity investigations. Initially, the ECC molecule was optimized by the density functional theory B3LYP method with a 6-311 G++ (d,p) basis set using the Gaussian 09 W program. The optimized molecular structure provides the harmonic vibrational frequencies of the ECC molecule. The observed and computed vibrational wavenumbers were assigned and found to be well correlated. UV-Vis absorption spectrum analysis indicates that the molecule contains π →π* and n → π* electronic transitions. The Frontier molecular orbital analysis confirmed the molecular reactivity and bioactivity of ECC, while the Mulliken atomic charge distribution analysis pinpointed the molecule’s reactive sites. Antibacterial testing demonstrated the ECC compound’s inhibitory effect on various bacterial strains, with a particular impact on Klebsiella pneumonia. In vitro, anticancer assessments showcased ECC's stronger inhibitory effects on A549 lung cancer cell lines compared to HeLa cervical cancer cell lines. Additionally, in silico molecular docking investigations provided further validation that the ECC compound can inhibit the function of the epidermal growth factor receptor, a factor associated with lung cancer. As a result, this study lays the foundation for the development of novel drugs for lung cancer treatment.
Hypselostomatidae Zilch 1959
Creators: name: Gojšina, Vukašin
name: Hunyadi, András
name: Sutcharit, Chirasak
name: Tongkerd, Piyoros
name: Auffenberg, Kurt
name: Grego, Jozef
name: Vermeulen, Jaap J.
name: Reischütz, Alexander
name: Páll-Gergely, Barna
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Stylommatophora
Hypselostomatidae

description: FamilyHypselostomatidae Zilch, 1959
Remarks.
Hypselostomatidae were originally introduced as a subfamily of Chondrinidae (Zilch 1959). In the same work, the subfamily Aulacospirinae Zilch, 1959 was erected, later synonymised by Schileyko (1998). Bouchet et al. (2017) treated Hypselostomatinae as a subfamily of Gastrocoptidae, while some authors used Hypselostomatidae (Páll-Gergely 2023 a, b; Páll-Gergely and White 2023; Gojšina et al. 2022) Vertiginidae (Panha 1998 a; Tanmuangpak and Dumrongrojwattana 2022) or Pupillidae (Burch and Panha 2002; Panha and Burch 2002 a) to classify these representatives.
description: Published as part of Gojšina, Vukašin, Hunyadi, András, Sutcharit, Chirasak, Tongkerd, Piyoros, Auffenberg, Kurt, Grego, Jozef, Vermeulen, Jaap J., Reischütz, Alexander & Páll-Gergely, Barna, 2025, A new start? Revision of the genera Anauchen, Bensonella, Gyliotrachela and Hypselostoma (Gastropoda, Eupulmonata, Hypselostomatidae) of Southeast Asia with description of 46 new species, pp. 1-338 in ZooKeys 1235 on pages 1-338, DOI: 10.3897/zookeys.1235.145281
Spectroscopic Characterization, Quantum Chemical, Molecular Docking, Antibacterial and Anticancer Studies on Ethyl Coumarin-3-Carboxylate: an Antibacterial and Lung Cancer Agent
Creators: name: Mohan, Surya S.
name: Meera, M.R.
name: Rathika, A.
name: Premkumar, R.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: The detailed theoretical and experimental (FT-IR, FT-Raman, UV-visible) spectroscopy analyses of the Ethyl Coumarin-3-Carboxylate (ECC) molecule were carried out. The ECC compound’s pharmacological properties were also investigated, utilizing antibacterial and anticancer activity investigations. Initially, the ECC molecule was optimized by the density functional theory B3LYP method with a 6-311 G++ (d,p) basis set using the Gaussian 09 W program. The optimized molecular structure provides the harmonic vibrational frequencies of the ECC molecule. The observed and computed vibrational wavenumbers were assigned and found to be well correlated. UV-Vis absorption spectrum analysis indicates that the molecule contains π →π* and n → π* electronic transitions. The Frontier molecular orbital analysis confirmed the molecular reactivity and bioactivity of ECC, while the Mulliken atomic charge distribution analysis pinpointed the molecule’s reactive sites. Antibacterial testing demonstrated the ECC compound’s inhibitory effect on various bacterial strains, with a particular impact on Klebsiella pneumonia. In vitro, anticancer assessments showcased ECC's stronger inhibitory effects on A549 lung cancer cell lines compared to HeLa cervical cancer cell lines. Additionally, in silico molecular docking investigations provided further validation that the ECC compound can inhibit the function of the epidermal growth factor receptor, a factor associated with lung cancer. As a result, this study lays the foundation for the development of novel drugs for lung cancer treatment.
Design, Synthesis of Novel Pyrido[2,3-d] pyrimidine Derivatives as SARS-CoV-2 Mpro Inhibitors for COVID-19 Therapy
Creators: name: Mansour, Eman
name: Sayed, Ahmed M.
name: Elewa, Safaa I.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Some of the interesting pyrido[2,3-d] pyrimidines (3a, 3b), 4, (5a–d), (6a, b), 7–13, and (15a–c) based on uracil moiety were synthesized efficiently using a conventional method and ultrasonic irradiation. Heterocyclic scaffolds such as pyrido[2,3-d] pyrimidines are vital structural elements in drug discovery. Their interactions with different viral mechanistic pathways will be leveraged in future research to create heterocycle-based antivirals. Therefore, the purpose of this work is to demonstrate the anticipated contribution of heterocyclic scaffolds to the advancement and identification of SARS CoV-2 treatment, The newly synthesized compounds were characterized by spectral data, and screened for their binding activity toward the main protease of COVID-19 utilizing a molecular docking study, according to the outcome of our initial screening and docking study, the produced compounds 3a, 4, 6a, 13, 15b, and 15c achieved an evaluation in vitro using the SARS-CoV-2 Mpro utilizing the main protease assay, the results of the evaluation showed that the hydrazinylpyridopyrimidine 4 (IC50 value: 10.69 µM) and triazolopyrimidin 15c (IC50 value 8.723 µM) had the greatest inhibitory effects on SARS-CoV-2 Mpro. Additionally, this study was conducted to assess the inhibitory efficacy of the synthesized compounds 4 and 15c, which show moderate inhibition for the replication of SARS CoV-2. Additional molecular dynamics and docking simulations were performed to prove the binding mechanism of 15c.
The complete genome sequence of Neckar River virus confirms it to be a distinct member of the genus Tombusvirus in the family Tombusviridae
Creators: name: Tran, Thi Chi
name: Maiss, Edgar
name: Rose, Hanna
Publisher: name: Wien ; New York, NY : Springer
Year: 2023
Subjects: subject: DNA, Complementary
subject: Genome, Viral
subject: Open Reading Frames
subject: Phylogeny
subject: RNA, Viral
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit

description: Neckar River virus (NRV), first isolated from a water sample of the Neckar River (Germany) in the 1980s, was serologically characterized as a novel tombusvirus. In this study, the complete genome sequence was determined, and an infectious full-length cDNA clone was constructed. The genome organization of NRV (DSMZ PV-0270) resembles that of tombusviruses. The genome consists of 4739 nucleotides and contains five open reading frames (ORFs) and one additional putative ORF (pX) in the 3’-terminal region. Phylogenetic analysis and sequence comparisons confirmed NRV to be a member of the species Tombusvirus neckarfluminis in the genus Tombusvirus. The infectious full-length cDNA clone was constructed using Gibson assembly and subsequent infection of Nicotiana benthamiana plants by Rhizobium radiobacter inoculation. The virus derived from the full-length cDNA clone caused symptoms resembling those caused by the wild-type virus, but slightly milder.
Quadrupole transitions and quantum gates protected by continuous dynamic decoupling
Creators: name: Martínez-Lahuerta, V.J.
name: Pelzer, L.
name: Dietze, K.
name: Krinner, L.
name: Schmidt, P.O.
name: Hammerer, K.
Publisher: name: Philadelphia, PA : IOP Publishing
Year: 2023
Subjects: subject: dynamic decoupling
subject: optical clocks
subject: protected transitions
subject: quadrupole shift
subject: quadrupole transitions
subject: quantum gates
subject: Zeeman shift
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: Dynamical decoupling techniques are a versatile tool for engineering quantum states with tailored properties. In trapped ions, nested layers of continuous dynamical decoupling (CDD) by means of radio-frequency field dressing can cancel dominant magnetic and electric shifts and therefore provide highly prolonged coherence times of electronic states. Exploiting this enhancement for frequency metrology, quantum simulation or quantum computation, poses the challenge to combine the decoupling with laser-ion interactions for the quantum control of electronic and motional states of trapped ions. Ultimately, this will require running quantum gates on qubits from dressed decoupled states. We provide here a compact representation of nested CDD in trapped ions, and apply it to electronic S and D states and optical quadrupole transitions. Our treatment provides all effective transition frequencies and Rabi rates, as well as the effective selection rules of these transitions. On this basis, we discuss the possibility of combining CDD and Mølmer-Sørensen gates.
Shared values and experiences with a leader are associated with fusion with the leader, the will to fight, and personal well-being.
Creators: name: Carrasco Sánchez, Naroa
name: Gómez, Ángel
Publisher: name: Zenodo
Year: 2024
Subjects: identity fusion
will to fight

description: Poster presented by Naroa Carrasco at the 19th General Meeting of the European Association of Social Psychology in Krakow (2023) on shared values and experiences with a leader. Accorthing to studies led by UNED, these are associated with fusion with the leader, the will to fight, and personal well-being.
Geometric post-Newtonian description of massive spin-half particles in curved spacetime
Creators: name: Alibabaei, Ashkan
name: Schwartz, Philip K
name: Giulini, Domenico
Publisher: name: Bristol : IOP Publ.
Year: 2023
Subjects: subject: Dirac equation
subject: formal WKB-like expansion
subject: generalised Fermi normal coordinates
subject: post-Newtonian expansion
subject: quantum matter in gravity
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: We consider the Dirac equation coupled to an external electromagnetic field in curved four-dimensional spacetime with a given timelike worldline γ representing a classical clock. We use generalised Fermi normal coordinates in a tubular neighbourhood of γ and expand the Dirac equation up to, and including, the second order in the dimensionless parameter given by the ratio of the geodesic distance to the radii defined by spacetime curvature, linear acceleration of γ, and angular velocity of rotation of the employed spatial reference frame along γ. With respect to the time measured by the clock γ, we compute the Dirac Hamiltonian to that order. On top of this ‘weak-gravity’ expansion we then perform a post-Newtonian expansion up to, and including, the second order of 1 / c , corresponding to a ‘slow-velocity’ expansion with respect to γ. As a result of these combined expansions we give the weak-gravity post-Newtonian expression for the Pauli Hamiltonian of a spin-half particle in an external electromagnetic field. This extends and partially corrects recent results from the literature, which we discuss and compare in some detail.
Therapeutic Properties of the Designer Cytokine IC7Fc to Treat Metabolic Diseases
Creators: name: ZHAO, JINGJING
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 310110
subject: Receptors and membrane biology
classificationCode: 321405
subject: Pharmaceutical sciences

description: This study explores the therapeutic potential of the designer cytokine IC7Fc in metabolic diseases in both periphery and central nervous systems (CNS), with a specific focus on metabolic dysfunction-associated steatohepatitis (MASH). Utilizing different mouse models, we delivered IC7Fc peripherally and centrally, and demonstrated that IC7Fc is potent in improving energy homeostasis when delivered in both ways. It signals exclusively in classical signalling pathway in periphery, thus, is an anti-inflammatory and viable treatment for metabolic diseases. However, both classical and trans-signalling pathways might participate in its central effects. IC7Fc is also effective in improving MASH progression in a dose-dependent manner and could be developed into a potential therapy for MASH in the future.