cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Experimental studies into the pathophysiology of syringomyelia
Creators: name: Hemley, Sarah J.
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Syringomyelia, a condition in which an enlarging cyst forms within the spinal cord, can result in motor weakness and pain. The pathogenesis of syringomyelia is poorly understood and treatment outcomes are not always satisfactory. It is unlikely that more effective therapies will be developed without a greater understanding of the mechanisms underlying spinal cord cyst formation. It is generally thought that syringomyelia is simply caused by an increase in the flow of cerebrospinal fluid (CSF) into the spinal cord. However, the pathogenesis is likely to be complex and multifactorial. It was proposed that: 1) a possible contribution to fluid flow is from vessels adjacent to the cyst, through a deficiency in the blood-spinal cord barrier (BSCB); 2) an increase in the expression of the water channel protein aquaporin-4 (AQP4) could increase the movement of water into the cyst; and 3) fluid outflow contributes to the pathology. Well established animal models of posttraumatic and Chiari-associated syringomyelia were used to study BSCB integrity, AQP4 expression and fluid outflow pathways. Integrity of the BSCB was assessed using immunoreactivity to endothelial barrier antigen and by extravasation of intravascular horseradish peroxidase (HRP). Western blotting and immunofluorescence was used to examine AQP4 and glial fibrillary acidic protein (GFAP) expression. Outflow of fluid was investigated by the direct microinjection of tracer into cysts under ultrasound guidance. These studies demonstrated a prolonged disruption of the BSCB directly surrounding the cyst. This disruption may be allowing a greater volume of fluid to pass from the blood stream into the spinal cord, causing the cyst to enlarge. There was a change in the levels of AQP4, suggesting that there is an imbalance in the water movement in the spinal cord. This imbalance may be contributing to fluid accumulation in syringomyelia. The study of fluid outflow found that fluid diffuses out of cysts into the surrounding extracellular space and perivascular spaces. This is the first study to demonstrate a route for fluid flow out of the cyst and will add to our understanding of fluid movement in syringomyelia.
Computational and in vitro insights on snake venom phospholipase A2 inhibitor of phytocompound ikshusterol3-O-glucoside of Clematis gouriana Roxb. ex DC.
Creators: name: Karthikeyan Muthusamy
name: Sathishkumar Chinnasamy
name: Subbiah Nagarajan
name: Sivaraman, Thirunavukkarasu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Ikshusterol3-O-glucoside was isolated from Clematis gouriana Roxb. ex DC. root. A structure of the isolated compound was determined on the basis of various spectroscopic interpretations (UV, NMR, FTIR, and GC-MS-EI). This structure was submitted in the PubChem compound database (SID 249494133). SID 249494133 was carried out by density functional theory calculation to observe the chemical stability and electrostatic potential of this compound. The absorption, distribution, metabolism, and excretion property of this compound was predicted to evaluate the drug likeness and toxicity. In addition, molecular docking, quantum polarized ligand docking, prime MMGBSA calculation, and induced fit docking were performed to predict the binding status of SID 249494133 with the active site of phospholipase A2 (PLA2) (PDB ID: 1A3D). The stability of the compound in the active site of PLA2 was carried out using molecular dynamics simulation. Further, the anti-venom activity of the compound was assessed using the PLA2 assay against Naja naja (Indian cobra) crude venom. The results strongly show that Ikshusterol3-O-glucoside has a potent snake-venom neutralizing capacity and it might be a potential molecule for the therapeutic treatment for snakebites.
MOESM1 of Musashi2 contributes to the maintenance of CD44v6+ liver cancer stem cells via notch1 signaling pathway
Creators: name: Wang, Xiju
name: Wang, Ronghua
name: Bai, Shuya
name: Xiong, Si
name: Li, Yawen
name: Liu, Man
name: Zhao, Zhenxiong
name: Wang, Yun
name: Zhao, Yuchong
name: Chen, Wei
name: Billiar, Timothy
name: Cheng, Bin
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 1: Figure S1 A. Western blot analysis of CD44v6 and MSI2 protein levels in HCC tissues and adjacent non-tumor tissues selected randomly. β-actin was used as a normalized control. B, C and D. IHC staining for CD44v6 and MSI2 and intensity of staining was evaluated as described in methods. For each marker, representative images were shown demonstrating each of intensity grades of staining. Scale bar, 50 μm. Figure S2 A and B. CD44v6 expression levels varied in human hepatic L02 cells and HCC cell lines (HepG2, MHCC-97L, SMMC-7721, HLE, Huh-7, MHCC-97h and SNU-398) by flow cytometry analysis. C. Representative FACS of CD44v6+ and CD44v6- populations, which isolated from SNU-398 and MHCC-97h cell lines by magnetic bead sorting.
Reinforcement Learning by Guided Safe Exploration
Creators: name: Yang, Qisong
name: Simão, Thiago D.
name: Jansen, Nils
name: Tindemans, Simon H.
name: Spaan, Matthijs T. J.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Safety is critical to broadening the application of reinforcement learning (RL). Often, we train RL agents in a controlled environment, such as a laboratory, before deploying them in the real world. However, the real-world target task might be unknown prior to deployment. Reward-free RL trains an agent without the reward to adapt quickly once the reward is revealed. We consider the constrained reward-free setting, where an agent (the guide) learns to explore safely without the reward signal. This agent is trained in a controlled environment, which allows unsafe interactions and still provides the safety signal. After the target task is revealed, safety violations are not allowed anymore. Thus, the guide is leveraged to compose a safe behaviour policy. Drawing from transfer learning, we also regularize a target policy (the student) towards the guide while the student is unreliable and gradually eliminate the influence of the guide as training progresses. The empirical analysis shows that this method can achieve safe transfer learning and helps the student solve the target task faster.
description: Accecpted at ECAI 2023
(3+1)-dimensional topological phases and self-dual quantum geometries encoded on Heegard surfaces
Creators: name: Dittrich, Bianca
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We apply the recently suggested strategy to lift state spaces and operators for (2+1)-dimensional topological quantum field theories to state spaces and operators for a (3+1)-dimensional TQFT with defects. We start from the (2+1)-dimensional Turaev-Viro theory and obtain a state space, consistent with the state space expected from the Crane-Yetter model with line defects. This work has important applications for quantum gravity as well as the theory of topological phases in (3+1) dimensions. It provides a self-dual quantum geometry realization based on a vacuum state peaked on a homogeneously curved geometry. The state spaces and operators we construct here provide also an improved version of the Walker-Wang model, and simplify its analysis considerably. We in particular show that the fusion bases of the (2+1)-dimensional theory lead to a rich set of bases for the (3+1)-dimensional theory. This includes a quantum deformed spin network basis, which in a loop quantum gravity context diagonalizes spatial geometry operators. We also obtain a dual curvature basis, that diagonalizes the Walker-Wang Hamiltonian. Furthermore, the construction presented here can be generalized to provide state spaces for the recently introduced dichromatic four-dimensional manifold invariants.
description: 27 pages, many figures, v2: minor corrections
37, 2⁰ le matin in translation: interpreting and transforming the voice of the other in literary translation
Creators: name: Borrey, Estelle Hélène
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This thesis comprises a case study in literary translation. As such, it presents a comparative translation analysis of Philippe Djian's 1985 French novel 37, 2° Le matin. This text is compared with two other corpus texts, namely Howard Buten's English translation, published in 1988 and known as Betty Blue: The Story of a Passion, and Daniele Petruccioli's 2010 Italian translation entitled 37° 2 al mattino. The two translations are examined both as literary texts in their own right, and as translations which recreate the French text that they interpret. My thesis is an investigation and evaluation of how specific contexts of production, reception, and circulation shape, and are in turn shaped by, the aforementioned corpus texts. As part of the investigation and evaluation of these contexts, Petruccioli's experience as a translator of Djian's texts is explored. My findings are supported by secondary sources and my own original research. Both Petruccioli and the translator in general are perceived as creators and "performers" of texts in translation. Literary translation is regarded in the context of this thesis as a complex textual performance which combines elements of creativity with intercultural and interlingual skills and sensibilities. Ultimately, it is argued that whilst Buten's 1988 English translation is commendable in many respects, it also contains some questionable elements, including examples of domestication, omissions, and mistranslations. I propose these can be avoided with the adoption of a semantic approach underpinned by a pro-foreignisation ethos. Although I critique some of the more significant omissions and mistranslations in Buten's text, the main thrust of my argument focuses on an evaluation of the strong domestication tendency evident throughout it. This tendency is presented as the fundamental reason that underpins the call for a retranslation of Djian's 37, 2° Le matin in English advanced herein. In addition to translation theory, my claims draw upon and are principally supported by postmodernist perspectives on interpretation, authorship, and the creation of meaning, and Lawrence Venuti's foreignisation and domestication paradigm as well as skopos theory. This last paradigm is developed and outlined by Katharina Reiss, Hans Vermeer, and Christiane Nord.
Explore Inert Dark Matter Blind Spots with Gravitational Wave Signatures
Creators: name: Huang, Fa Peng
name: Yu, Jiang-Hao
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Motivated by the absence of dark matter signals in direct detection experiments and the discovery of gravitational waves (GWs) at aLIGO, we discuss the possibility to explore a generic classes of scalar dark matter models using the complementary searches via phase transition gravitational waves and the future lepton collider signatures. We focus on the inert scalar multiplet dark matter models and the mixed inert scalar dark matter models, which could undergo a strong first-order phase transitions during the evolution of the early universe, and might produce detectable phase transition GW signals at future GW experiments, such as eLISA, DECIGO and BBO. We find that the future GW signature, together with circular electron-positron collider, could further explore the model's blind spot parameter region, at which the dark matter-Higgs coupling is identically zero, thus avoiding the dark matter spin-independent direct detection constraints.
description: 10 pages, 3 figures
title: ADCO, Grènetier de Cîteaux : comptes (1497-1504) (11 H 1172), f. 00502
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172), f. 00502, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: abbaye de Cîteaux
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: http://www.wikidata.org/entity/Q843261
Energy dissipative solutions to the Kobayashi-Warren-Carter system
Creators: name: Moll, Salvador
name: Shirakawa, Ken
name: Watanabe, Hiroshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35K87, 35R06, 35K67

description: In this paper we study a variational system of two parabolic PDEs, called the Kobayashi-Warren-Carter system, which models the grain boundary motion in a polycrystal. The focus of the study is the existence of solutions to this system which dissipate the associated energy functional. We obtain existence of this type of solutions via a suitable approximation of the energy functional with Laplacians and an extra regularization of the weighted total variation term of the energy. As a byproduct of this result, we also prove some $Γ$-convergence results concerning weighted total variations and the corresponding time-dependent cases. Finally, the regularity obtained for the solutions together with the energy dissipation property, permits us to completely characterize the $ω$-limit set of the solutions.
description: 36 pages
Multi Agent Navigation in Unconstrained Environments using a Centralized Attention based Graphical Neural Network Controller
Creators: name: Ma, Yining
name: Khan, Qadeer
name: Cremers, Daniel
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences

description: In this work, we propose a learning based neural model that provides both the longitudinal and lateral control commands to simultaneously navigate multiple vehicles. The goal is to ensure that each vehicle reaches a desired target state without colliding with any other vehicle or obstacle in an unconstrained environment. The model utilizes an attention based Graphical Neural Network paradigm that takes into consideration the state of all the surrounding vehicles to make an informed decision. This allows each vehicle to smoothly reach its destination while also evading collision with the other agents. The data and corresponding labels for training such a network is obtained using an optimization based procedure. Experimental results demonstrates that our model is powerful enough to generalize even to situations with more vehicles than in the training data. Our method also outperforms comparable graphical neural network architectures. Project page which includes the code and supplementary information can be found at https://yininghase.github.io/multi-agent-control/
MOESM7 of Genome-wide identification and characterization of the ALOG gene family in Petunia
Creators: name: Chen, Feng
name: Zhou, Qin
name: Wu, Lan
name: Li, Fei
name: Liu, Baojun
name: Zhang, Shuting
name: Zhang, Jiaqi
name: Bao, Manzhu
name: Liu, Guofeng
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Additional file 7. Multiple alignments of 11 PhLSH proteins. The similarity of the N- and C-terminal sequences is very low. Sequences were colored based on 75% consistency. The absolutely conserved residues are shown in light purple.
title: ADCO, Cinquième cartulaire de Saint-Étienne de Dijon (1664), Cart. 28 (G 132), 258 folios, f. 00438
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00438, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00438, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: http://www.wikidata.org/entity/Q15945019
description: Provenance: abbaye Saint-Étienne de Dijon
Generalized Early Stopping in Evolutionary Direct Policy Search
Creators: name: Arza, Etor
name: Goff, Leni K. Le
name: Hart, Emma
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: Neural and Evolutionary Computing (cs.NE)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Lengthy evaluation times are common in many optimization problems such as direct policy search tasks, especially when they involve conducting evaluations in the physical world, e.g. in robotics applications. Often when evaluating solution over a fixed time period it becomes clear that the objective value will not increase with additional computation time (for example when a two wheeled robot continuously spins on the spot). In such cases, it makes sense to stop the evaluation early to save computation time. However, most approaches to stop the evaluation are problem specific and need to be specifically designed for the task at hand. Therefore, we propose an early stopping method for direct policy search. The proposed method only looks at the objective value at each time step and requires no problem specific knowledge. We test the introduced stopping criterion in five direct policy search environments drawn from games, robotics and classic control domains, and show that it can save up to 75% of the computation time. We also compare it with problem specific stopping criteria and show that it performs comparably, while being more generally applicable.
Serum and plasma amino acids as markers of prediabetes, insulin resistance, and incident diabetes
Creators: name: C. Gar
name: M. Rottenkolber
name: C. Prehn
name: J. Adamski
name: J. Seissler
name: A. Lechner
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Presently, routine screening misses many cases of prediabetes and early type 2 diabetes (T2D). Therefore, better biomarkers are needed for a simple and early detection of abnormalities of glucose metabolism and prediction of future T2D. Possible candidates for this include plasma or serum amino acids because glucose and amino acid metabolism are closely connected. This review presents the available evidence of this connectivity and discusses its clinical implications. First, we examine the underlying physiological, pre-analytical, and analytical issues. Then, we summarize results of human studies that evaluate amino acid levels as markers for insulin resistance, prediabetes, and future incident T2D. Finally, we illustrate the interconnection of amino acid levels and metabolic syndrome with our own data from a deeply phenotyped human cohort. We also discuss how amino acids may contribute to the pathophysiology of T2D. We conclude that elevated branched-chain amino acids and reduced glycine are currently the most robust and consistent amino acid markers for prediabetes, insulin resistance, and future T2D. Yet, we are cautious regarding the clinical potential even of these parameters because their discriminatory power is insufficient and their levels depend not only on glycemia, but also on other components of the metabolic syndrome. The identification of more precise intermediates of amino acid metabolism or combinations with other biomarkers will, therefore, be necessary to obtain in order to develop laboratory tests that can improve T2D screening.
Shortcuts to adiabaticity in the presence of a continuum: applications to itinerant quantum state transfer
Creators: name: Baksic, Alexandre
name: Belyansky, Ron
name: Ribeiro, Hugo
name: Clerk, Aashish A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present a method for accelerating adiabatic protocols for systems involving a coupling to a continuum, one that cancels both non-adiabatic errors as well as errors due to dissipation. We focus on applications to a generic quantum state transfer problem, where the goal is to transfer a state between a single level or mode, and a propagating temporal mode in a waveguide or transmission line. Our approach enables perfect adiabatic transfer protocols in this setup, despite a finite protocol speed and a finite waveguide coupling. Our approach even works in highly constrained settings, where there is only a single time-dependent control field available.
MOESM2 of Musashi2 contributes to the maintenance of CD44v6+ liver cancer stem cells via notch1 signaling pathway
Creators: name: Wang, Xiju
name: Wang, Ronghua
name: Bai, Shuya
name: Xiong, Si
name: Li, Yawen
name: Liu, Man
name: Zhao, Zhenxiong
name: Wang, Yun
name: Zhao, Yuchong
name: Chen, Wei
name: Billiar, Timothy
name: Cheng, Bin
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 2: Figure S3 A. Overexpression of MSI2 increased self-renewal property in vitro in CD44v6- SNU-398 cells, Scale bar, 200 μm. B and C. Transwell migration and invasion assays showed that up-regulation of MSI2 increased the migration and invasion capacity of CD44v6- SNU-398 cells. Scale bar, 200 μm. D. Colony formation assays showed the ability of cell proliferation and colony formation of CD44v6- SNU-398 cells was enhanced when MSI2 was up-regulated. E. 1×105 of Lv MSI2 cells and the corresponding controls were injected into the left lobes of liver. Bioluminescence signals from Lv MSI2 group were stronger than those from the corresponding control group. n=6. F. Overexpression of MSI2 increased the expression of stemness-related genes in CD44v6- SNU-398 cells. G. CCK8 toxic assay showed that MSI2 shRNA cells were less resistant to Sorafenib than the control cells. H. RT-PCR showed that the inhibition of MSI2 decreased the expression of stemness-related genes in CD44v6+ SNU-398 cells. For statistical analysis, *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001, t test. Figure S4 A. Notch1 signaling pathway was inhibited by Notch1 shRNA lentivirus. B. Notch1 signaling pathway was inhibited by γ-secretase inhibitor RO4929097. C. The inhibition of Notch1 signaling decreased self-renewal property in vitro in CD44v6+ SNU-398 cells, Scale bar, 200 μm. D and E. Transwell migration and invasion assay showed that the inhibition of Notch1 signaling decreased the migration and invasion capacity of CD44v6+ SNU-398 cells. Scale bar, 200 μm. F. Colony formation assays showed that the ability of cell proliferation and colony formation of CD44v6+ SNU-398 cells was inhibited when Notch1 signaling was inhibited. G. The inhibition of Notch1 signaling in CD44v6+ SNU-398 cells decreased the expression of stemness-related genes. For statistical analysis, **p < 0.01 and ***p < 0.001, t test.
Berufsentwicklung der Soziokulturellen Animation - Strang II : ein empirischer Beitrag zur fortlaufenden Berufsentwicklung in zwei Diplom-/Bachelorarbeiten - Strang I und II
Creators: name: Scheidegger, Nico
name: Süsstrunk, Simon
Publisher: name: Zenodo
Year: 2008
Subjects: Soziokulturelle Animation
Berufsfeld
Berufsbild
Berufspraxis
Professionalisierung

description: Abstract Diese Diplom-/Bachelorarbeit vermittelt ein aktuelles Bild der Berufsentwicklung der Soziokulturellen Animation. Berufsentwicklung meint die Entwicklung eines Berufs auf verschiedenen Ebenen und definiert sich durch das Zusammenwirken von Berufsidentität, -praxis, und -theorie. Im Zentrum dieser Arbeit steht die Frage nach einer idealen, fortlaufenden Berufsentwicklung, welche aktuellen Anforderungen und Bedürfnissen Rechnung tragen kann. Im Rahmen der Untersuchungen zum Thema Berufsentwicklung konnten auf den drei oben genannten Ebenen, unterschiedliche Themenschwerpunkte eingegrenzt werden. Folgende sieben Schwerpunkte sind für die Berufsentwicklung zentral und befinden sich in einer Wechselwirkung zueinander: Vernetzung, Berufsidentität, Professionalisierung, Ökonomisierung, Ressourcenbündelung, Ausbildung sowie Forschung und Theorie. In dieser Arbeit wird eine institutionalisierte Einrichtung mit explizitem Auftrag zur Berufsentwicklung der Soziokulturellen Animation entworfen. Dieser Entwurf umfasst ein Modell für eine aktive Berufsentwicklung, unter Berücksichtigung der genannten Themenschwerpunkte. Dadurch sollen unter anderem die Berufsidentität, der Ressourcenaustausch oder die Berufsfelderweiterung der Soziokulturellen Animation gestärkt werden. Diese Forschungsarbeit wurde in enger Kooperation mit einem zweiten Bachelorarbeitsteam entwickelt. Im dafür konzipierten Doppelstrangsystem wird die Thematik der Berufsentwicklung aus verschiedenen Perspektiven analysiert.
description: + Code Diss LU: hslusa basa 2008 be + Fussnote: Bachelor-Arbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialarbeit, 2008 + NL-Code: NLLUHSA200808
Morphological processing in adults and children during visual word recognition
Creators: name: Beyersmann, Elisabeth
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The research presented in this thesis examines cognitive processes involved in the recognition of written morphologically complex words in skilled readers and the acquisition of these mechanisms in developing readers. All experiments focus on non-strategic aspects of rapid morphological segmentation, exploring the nature of underlying lower-level orthographic processing constraints in morphological decomposition. The influences of orthographic processing constraints upon morphological processing are explored by distinguishing between lower-level morpho-orthographic and higher-lever morpho-semantic processing mechanisms. The introductory thesis chapter reviews evidence of different forms of purely structural non-semantic morphological processes and discusses the implication for morphological processing theories as well as orthographic processing theories. The role of morphological decomposition in visual word recognition is then examined across four different chapters (testing 446 adult participants and 72 children), in both English and Spanish native speakers. To explore non-conscious stages of cognitive processing, the present research draws upon the masked priming paradigm, providing a window into early, automatic processes in visual word recognition. In Chapters 2, 3, and 4, a novel approach is used combining the masked priming paradigm with the transposed-letter priming paradigm to examine if and how the encoding of morphological information is modulated by lower-level letter position processing mechanisms, in skilled readers. The final chapter provides a summary of the presented findings across all chapters and gives an outlook on future research prospects. We conclude that morphological processing in both skilled and developing readers is based on both morphoorthographic and morpho-semantic processing mechanism, which we discuss in the context of current morphological processing theories.
MPEC 2024-U197 : 2024 TU38
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 TU38

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
On the Galilean covariance of the d'Alembert equation for acoustic phenomena
Creators: name: Caruso, Francisco
name: Oguri, Vitor
name: Silveira, Felipe
Publisher: name: arXiv
Year: 2023
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: The covariance of the d'Alembert equation for acoustic phenomena -- which is a mechanical wave equation -- under the conventional Galilean transformation is demonstrated without the need to abandon the hypothesis that time is absolute in Classical Mechanics, {what would imply} a modification of Galileo's transformations, as suggested in a paper recently published in this journal.
description: 4 pages, 1 figure
Overall properties of the Gaia DR1 reference frame
Creators: name: Liu, N.
name: Zhu, Z.
name: Liu, J. -C.
name: Ding, C. -Y.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We compare quasar positions of the auxiliary quasar solution with ICRF2 sources using different samples and evaluate the influence on the {\it Gaia} DR1 reference frame owing to the Galactic aberration effect over the J2000.0-J20015.0 period. Then we estimate the global rotation between TGAS with {\it Tycho}-2 proper motion systems to investigate the property of the {\it Gaia} DR1 reference frame. Finally, the Galactic kinematics analysis using the K-M giant proper motions is performed to understand the property of {\it Gaia} DR1 reference frame. The positional comparison between the auxiliary quasar solution and ICRF2 shows negligible orientation and validates the declination bias of $\sim$$-0.1$\mas~in {\it Gaia} quasar positions with respect to ICRF2. Galactic aberration effect is thought to cause an offset $\sim$$0.01$\mas~of the $Z$ axis direction of {\it Gaia} DR1 reference frame. The global rotation between TGAS and {\it Tycho}-2 proper motion systems, obtained by different samples, shows a much smaller value than the claimed value $0.24$\masyr. For the Galactic kinematics analysis of the TGAS K-M giants, we find possible non-zero Galactic rotation components beyond the classical Oort constants: the rigid part $ω_{Y_G} = -0.38 \pm 0.15$\masyr~and the differential part $ω^\prime_{Y_G} = -0.29 \pm 0.19$\masyr~around the $Y_G$ axis of Galactic coordinates, which indicates possible residual rotation in {\it Gaia} DR1 reference frame or problems in the current Galactic kinematical model.
description: 6 pages, 1 figure. Accepted for publication in A&A
Spontaneous Symmetry Breaking of Time-Reversal-Symmetry and Time-Crystal States in Chiral Atomic Systems
Creators: name: Silveirinha, Mário G.
name: Terças, Hugo
name: Antezza, Mauro
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present a theoretical study of the interaction between an atom characterized by a degenerate ground state and a reciprocal environment, such as a semiconductor nanoparticle, without the presence of external bias. Our analysis reveals that the combined influence of the electron's intrinsic spin magnetic moment on the environment and the chiral atomic dipolar transitions may lead to either the spontaneous breaking of time-reversal symmetry or the emergence of time-crystal-like states with remarkably long relaxation times. The different behavior is ruled by the handedness of the precession motion of the atom's spin vector, which is induced by virtual chiral-dipolar transitions. Specifically, when the relative orientation of the precession angular velocity and the electron spin vector is as in a spinning top, the system manifests time-crystal-like states. Conversely, with the opposite relative orientation, the system experiences spontaneous symmetry breaking of time-reversal symmetry. Our findings introduce a novel mechanism for the spontaneous breaking of time-reversal symmetry in atomic systems, and unveil an exciting opportunity to engineer a nonreciprocal response at the nanoscale, exclusively driven by the quantum vacuum fluctuations.
description: 62 pages
Inducing room-temperature valley polarization of excitonic emission in transition metal dichalcogenide monolayers
Creators: name: Morozov, Sergii
name: Yezekyan, Torgom
name: Wolff, Christian
name: Bozhevolnyi, Sergey I.
name: Mortensen, N. Asger
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The lowest energy states in transition metal dichalcogenide (TMD) monolayers follow valley selection rules, which have attracted vast interest due to the possibility of encoding and processing of quantum information. However, these quantum states are strongly affected by the temperature-dependent intervalley scattering causing complete valley depolarization, which is hampering any practical applications of TMD monolayers at room temperature. Therefore, for achieving clear and robust valley polarization in TMD monolayers one needs to suppress parasitic depolarization processes, which is the central challenge in the growing field of valleytronics. Here, in electron-doping experiments on TMD monolayers, we demonstrate that strong doping levels beyond $10^{13}$~cm$^{-2}$ can induce 61\% and 37\% valley contrast at room temperature in tungsten diselenide and molybdenum diselenide monolayers, respectively. Our results indicate that charged excitons in TMD monolayers can be utilized as quantum units in designing of practical valleytronic devices operating at 300 K.
Supplementary files
Creators: name: Bertolini, Francesca
Publisher: name: figshare
Year: 2017
Subjects: subject: 70201 Animal Breeding
subject: FOS: Animal and dairy science

description: Supplementary word for A genomic investigation of Porcine Periweaning Failure to Thrive Syndrome (PFTS)
MOESM8 of Genome-wide identification and characterization of the ALOG gene family in Petunia
Creators: name: Chen, Feng
name: Zhou, Qin
name: Wu, Lan
name: Li, Fei
name: Liu, Baojun
name: Zhang, Shuting
name: Zhang, Jiaqi
name: Bao, Manzhu
name: Liu, Guofeng
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Virology
subject: Computational Biology

description: Additional file 8. Detailed characteristics of the motifs in the PhLSH proteins.
Compact high voltage low power ionizing power supply
Creators: name: De Pedro, Kevin
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: At high velocities, drag is the dominating factor in fuel consumption by a vehicle moving through air. Strategic design chief at Volvo's Monitoring & Concept Center, Doug Frasher describes the drag coefficient as having decreased miles per gallon (mpg) by 1 mpg for every 0.1 increase in drag coefficient. Plasma actuators serve as an attractive solution to this problem, as they can control the flow of air around the body they are applied to, while maintaining a relatively light-weight, quick response time and require no moving parts in their construction. Limited knowledge is available in the application of these plasma actuators on smaller scale modes of transport. In these instances the plasma actuators must be able to sustain a glow discharge plasma in an environment inherent to car, functioning at an ambient pressure of one atmosphere as well as having a compact and light enough build. The devices should not substantially impede the functioning of the vehicle's performance and should be of actual benefit to the vehicle. Further, the plasma actuator's power consumption must be efficient. As batteries are the primary way in which vehicles receive electric power, the compact high voltage low power ionizing power supply should be designed to fulfil these requirements. In the undertaking of the project, the design decisions made for the power supply closely follow existing knowledge on John R. Roth's patented "one atmosphere uniform glow discharge plasma ( OAUGDP)", as well as the works of Jean-Louis Naudin and Thomas C. Corke et al. in their efforts to explain and optimize the details of Roth's work. Here their techniques will be assessed and evaluated through simulation and experimentation. If they are deemed favourable in fulfilling the requirements of the compact high voltage ionizing power supply, they will be incorporated into the design (CHVLPIPS). The CHVLPIPS, though far from complete, is proceeding well. What has been achieved is the generation of plasma using a battery that at a visual standpoint is comparable to works published in regards to plasma actuators. The CHVLPIPS' form factor and weight is far less cumbersome than the laboratory power supplies generally used. What has been contributed as a result of this undertaking are the first few steps towards a potential streamlined use of plasma actuators.
Effects of Reactive Social Distancing on the 1918 Influenza Pandemic
Creators: name: Yu, Duo
name: Lin, Qianying
name: Chiu, Alice PY
name: He, Daihai
Publisher: name: arXiv
Year: 2017
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: The 1918 influenza pandemic was characterized by multiple epidemic waves. We investigated into reactive social distancing, a form of behavioral responses, and its effect on the multiple influenza waves in the United Kingdom. Two forms of reactive social distancing have been used in previous studies: Power function, which is a function of the proportion of recent influenza mortality in a population, and Hill function, which is a function of the actual number of recent influenza mortality. Using a simple epidemic model with a Power function and one common set of parameters, we provided a good model fit for the observed multiple epidemic waves in London boroughs, Birmingham and Liverpool. Our approach is different from previous studies where separate models are fitted to each city. We then applied these model parameters obtained from fitting three cities to all 334 administrative units in England and Wales and including the population sizes of individual administrative units. We computed the Pearson's correlation between the observed and simulated data for each administrative unit. We achieved a median correlation of 0.636, indicating our model predictions perform reasonably well. Our modelling approach which requires reduced number of parameters resulted in computational efficiency gain without over-fitting the model. Our works have both scientific and public health significance.
description: 11 pages, 5 figures
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0870
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2012
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0870, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0870, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Pressure Driven Fractionalization of Ionic Spins Results in Cupratelike High-$T_c$ Superconductivity in La$_3$Ni$_2$O$_7$
Creators: name: Jiang, Ruoshi
name: Hou, Jinning
name: Fan, Zhiyu
name: Lang, Zi-Jian
name: Ku, Wei
Publisher: name: arXiv
Year: 2023
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Beyond 14GPa of pressure, bi-layered La$_3$Ni$_2$O$_7$ was recently found to develop strong superconductivity above the liquid nitrogen boiling temperature. An immediate essential question is the pressure-induced qualitative change of electronic structure that enables the exciting high-temperature superconductivity. We investigate this timely question via a numerical multi-scale derivation of effective many-body physics. At the atomic scale, we first clarify that the system has a strong charge transfer nature with itinerant carriers residing mainly in the in-plane oxygen between spin-1 Ni$^{2+}$ ions. We then elucidate in eV- and sub-eV-scale the key physical effect of the applied pressure: It induces a cupratelike electronic structure through partially screening the Ni spin from 1 to 1/2. This suggests a high-temperature superconductivity in La$_3$Ni$_2$O$_7$ with microscopic mechanism and ($d$-wave) symmetry similar to that in the cuprates.
description: 12 pages with 11 figures and 3 tables
The Unruh Effect for Eccentric Uniformly Rotating Observers
Creators: name: Ramezani-Aval, H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is common to use Galilean rotational transformation to investigate the Unruh effect for uniformly rotating observers. However, the rotating observer in this subject is an eccentric observer while Galilean rotational transformation is only valid for centrally rotating observers. Thus, the reliability of the results of applying Galilean rotational transformation to the study of the Unruh effect might be considered as questionable. In this work the rotational analog of the Unruh effect is investigated by employing two relativistic rotational transformations corresponding to the eccentric rotating observer, and it is shown that in both cases the detector response function is non-zero. It is also shown that although consecutive Lorentz transformations can not give a frame within which the canonical construction can be carried out, the expectation value of particle number operator in canonical approach will be zero if we use modified Franklin transformation. These conclusions reinforce the claim that correspondence between vacuum states defined via canonical field theory and a detector is broken for rotating observers. Some previous conclusions are commented on and some controversies are also discussed.
Applying the methodology of Design of Experiments to stability studies: a Partial Least Squares approach for evaluation of drug stability
Creators: name: Jordan, Nika
name: Zakrajšek, Jure
name: Bohanec, Simona
name: Roškar, Robert
name: Grabnar, Iztok
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology

description: The aim of the present research is to show that the methodology of Design of Experiments can be applied to stability data evaluation, as they can be seen as multi-factor and multi-level experimental designs. Linear regression analysis is usually an approach for analyzing stability data, but multivariate statistical methods could also be used to assess drug stability during the development phase. Data from a stability study for a pharmaceutical product with hydrochlorothiazide (HCTZ) as an unstable drug substance was used as a case example in this paper. The design space of the stability study was modeled using Umetrics MODDE 10.1 software. We showed that a Partial Least Squares model could be used for a multi-dimensional presentation of all data generated in a stability study and for determination of the relationship among factors that influence drug stability. It might also be used for stability predictions and potentially for the optimization of the extent of stability testing needed to determine shelf life and storage conditions, which would be time and cost-effective for the pharmaceutical industry.