cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On Edgeworth Expansions in Generalized Urn Models
Creators: name: Mirakhmedov, Sh. M.
name: Jammalamadaka, S. Rao
name: Mohamed, Ibrahim B.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 62G20, 60F05

description: The random vector of frequencies in a generalized urn model is viewed as conditionally independent random variables, given their sum. Such a representation is exploited to derive Edgeworth expansions for a sum of functions of such frequencies. Applying these results to urn models such as with- and without-replacement sampling schemes as well as the multicolor Polya-Egenberger model, new results are obtained for the chi-square statistic, for the sample sum in a without replacement scheme, and for the so-called Dixon statistic that is useful in comparing two samples.
description: Journal of Theoretical Probability. 2012
Dynamical orbital evolution of asteroids and planetesimals across distinct chemical reservoirs due to accretion growth of planets in the early solar system
Creators: name: Sahijpal, Sandeep
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: N-body numerical simulations code for the orbital motion of asteroids/planetesimals within the asteroid belt under the gravitational influence of the sun and the accreting planets has been developed. The aim is to make qualitative, and to an extent a semi-quantitative argument, regarding the possible extent of radial mixing and homogenization of planetesimal reservoirs of the two observed distinct spectral types , viz., the S-type and C-type, across the heliocentric distances due to their dynamical orbital evolution, thereby, eventually leading to the possible accretion of asteroids having chemically diverse constituents. The spectral S-type and C-type asteroids are broadly considered as the parent bodies of the two observed major meteoritic dichotomy classes, namely, the non-carbonaceous (NC) and carbonaceous (CC) meteorites, respectively. The present analysis is performed to understand the evolution of the observed dichotomy and its implications due to the nebula and early planetary processes during the initial 10 Myrs (Million years). The homogenization across the two classes is studied in context to the accretion timescales of the planetesimals with respect to the half-life of the potent planetary heat source, 26Al. The accretion over a timescale of ~1.5 Myr. possibly resulted in the planetary-scale differentiation of planetesimals to produce CC and NC achondrites and iron meteorite parent bodies, whereas, the prolonged accretion over a timescale of 2-5 Myrs. resulted in the formation of CC and NC chondrites. Our simulation results indicate a significant role of the initial eccentricities and the masses of the accreting giant planets, specifically, Jupiter and Saturn, in triggering the eccentricity churning of the planetesimals across the radial distances......
description: Accepted
Exact Continuum Representation of Long-range Interacting Systems and Emerging Exotic Phases in Unconventional Superconductors
Creators: name: Buchheit, Andreas A.
name: Keßler, Torsten
name: Schuhmacher, Peter K.
name: Fauseweh, Benedikt
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mathematical Physics (math-ph)
subject: Number Theory (math.NT)
subject: Computational Physics (physics.comp-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Continuum limits are a powerful tool in the study of many-body systems, yet their validity is often unclear when long-range interactions are present. In this work, we rigorously address this issue and put forth an exact representation of long-range interacting lattices that separates the model into a term describing its continuous analog, the integral contribution, and a term that fully resolves the microstructure, the lattice contribution. For any system dimension, any lattice, any power-law interaction, and for linear, nonlinear, and multi-atomic lattices, we show that the lattice contribution can be described by a differential operator based on the multidimensional generalization of the Riemann zeta function, namely the Epstein zeta function. We employ our representation in Fourier space to solve the important problem of long-range interacting unconventional superconductors. We derive a generalized Bardeen--Cooper--Schrieffer gap equation and find emerging exotic phases in two-dimensional superconductors with topological phase transitions. Finally, we utilize non-equilibrium Higgs spectroscopy to analyze the impact of long-range interactions on the collective excitations of the condensate. We show that the interactions can be used to fine-tune the Higgs mode's stability, ranging from exponential decay of the oscillation amplitude up to complete stabilization.
A Post-Quantum Associative Memory
Creators: name: Lami, Ludovico
name: Goldwater, Daniel
name: Adesso, Gerardo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Artificial Intelligence (cs.AI)
subject: Information Theory (cs.IT)
subject: Mathematical Physics (math-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Associative memories are devices storing information that can be fully retrieved given partial disclosure of it. We examine a toy model of associative memory and the ultimate limitations it is subjected to within the framework of general probabilistic theories (GPTs), which represent the most general class of physical theories satisfying some basic operational axioms. We ask ourselves how large the dimension of a GPT should be so that it can accommodate $2^m$ states with the property that any $N$ of them are perfectly distinguishable. Call $d(N,m)$ the minimal such dimension. Invoking an old result by Danzer and Grünbaum, we prove that $d(2,m)=m+1$, to be compared with $O(2^m)$ when the GPT is required to be either classical or quantum. This yields an example of a task where GPTs outperform both classical and quantum theory exponentially. More generally, we resolve the case of fixed $N$ and asymptotically large $m$, proving that $d(N,m) \leq m^{1+o_N(1)}$ (as $m\to\infty$) for every $N\geq 2$, which yields again an exponential improvement over classical and quantum theories. Finally, we develop a numerical approach to the general problem of finding the largest $N$-wise mutually distinguishable set for a given GPT, which can be seen as an instance of the maximum clique problem on $N$-regular hypergraphs.
description: 27 pages, 5 figures. v2: Extended with new analytical and numerical results for N>2, showing that an exponential advantage persists for large post-quantum memories. v3 is close to the published version
Switching to biosimilars: current perspectives in immune-mediated inflammatory diseases
Creators: name: Edwards, Christopher J.
name: Hercogová, Jana
name: Albrand, Helene
name: Amiot, Aurelian
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Introduction: The expiry of patents for biologics has led to the introduction of biosimilars for the treatment of immune-mediated inflammatory diseases (IMIDs). These treatment alternatives may allow earlier and wider access to appropriate therapy for patients without increasing the economic burden on health-care systems. Prescription of biosimilars to treatment-naïve patients is well accepted; however, additional considerations must be taken into account when switching clinically stable patients from reference products to biosimilars. Area covered: We discuss the current considerations related to switching from reference products to biosimilars from a physician and patient perspective. We review the clinical data and real-life experience on switching patients with IMIDs, present the position of the relevant medical societies, and discuss the importance of patient–physician communication and need for shared decision-making. Expert opinion: The introduction of biosimilars provides an opportunity to expand access to treatment for patients with IMIDs across Europe and support the financial sustainability of health-care systems. We anticipate that as the real-world evidence base grows, confirming the results of clinical trials, there will be a corresponding increase in physician and patient acceptance, not only to initiating treatment with a biosimilar, but also to switching medication from a reference product to a biosimilar.
Transfer-Learning Across Datasets with Different Input Dimensions: An Algorithm and Analysis for the Linear Regression Case
Creators: name: Silvestrin, Luis Pedro
name: van Zanten, Harry
name: Hoogendoorn, Mark
name: Koole, Ger
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: With the development of new sensors and monitoring devices, more sources of data become available to be used as inputs for machine learning models. These can on the one hand help to improve the accuracy of a model. On the other hand, combining these new inputs with historical data remains a challenge that has not yet been studied in enough detail. In this work, we propose a transfer learning algorithm that combines new and historical data with different input dimensions. This approach is easy to implement, efficient, with computational complexity equivalent to the ordinary least-squares method, and requires no hyperparameter tuning, making it straightforward to apply when the new data is limited. Different from other approaches, we provide a rigorous theoretical study of its robustness, showing that it cannot be outperformed by a baseline that utilizes only the new data. Our approach achieves state-of-the-art performance on 9 real-life datasets, outperforming the linear DSFT, another linear transfer learning algorithm, and performing comparably to non-linear DSFT.
description: Manuscript accepted for publication at the Journal of Computational Mathematics and Data Science. Code available at https://github.com/lpsilvestrin/incremental_input_tl
QCD corrections to H -> gg in FDR
Creators: name: Pittau, Roberto
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: I apply FDR -- a recently introduced Four Dimensional Regularization approach to quantum field theories -- to compute the NLO QCD corrections to H -> gg in the large top mass limit. The calculation involves all key ingredients of massless QCD, namely ultraviolet, infrared and collinear divergences, besides alpha_s renormalization. I show in detail how the correct result emerges in FDR, and discuss the translation rules to dimensional regularization.
description: 15 pages, 2 figures
Resonant transport in a highly conducting single molecular junction via metal-metal covalent bond
Creators: name: Pabi, Biswajit
name: Marek, Štepán
name: Pal, Adwitiya
name: Kumari, Puja
name: Ray, Soumya Jyoti
name: Thakur, Arunabha
name: Korytár, Richard
name: Pal, Atindra Nath
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Achieving highly transmitting molecular junctions through resonant transport at low bias is key to the next-generation low-power molecular devices. Although, resonant transport in molecular junctions was observed by connecting a molecule between the metal electrodes via chemical anchors by applying a high source-drain bias (> 1V), the conductance was limited to < 0.1 G$_0$, G$_0$ being the quantum of conductance. Here, we report electronic transport measurements by directly connecting a Ferrocene molecule between Au electrodes at the ambient condition in a mechanically controllable break junction setup (MCBJ), revealing a conductance peak at ~ 0.2 G$_0$ in the conductance histogram. A similar experiment was repeated for Ferrocene terminated with amine (-NH2) and cyano (-CN) anchors, where conductance histograms exhibit an extended low conductance feature including the sharp high conductance peak, similar to pristine ferrocene. Statistical analysis of the data along with density functional theory-based transport calculation suggests the possible molecular conformation with a strong hybridization between the Au electrodes and Fe atom of Ferrocene molecule is responsible for a near-perfect transmission in the vicinity of the Fermi energy, leading to the resonant transport at a small applied bias (< 0.5V). Moreover, calculations including Van der Waals/dispersion corrections reveal a covalent like organometallic bonding between Au and the central Fe atom of Ferrocene, having bond energies of ~ 660 meV. Overall, our study not only demonstrates the realization of an air-stable highly transmitting molecular junction, but also provides an important insight about the nature of chemical bonding at the metal/organo-metallic interface.
description: 23 pages, 6 figures, supplementary included
Horizontal Visibility graphs generated by type-II intermittency
Creators: name: Núñez, Ángel M.
name: Gómez, José Patricio
name: Lacasa, Lucas
Publisher: name: arXiv
Year: 2013
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: In this contribution we study the onset of chaos via type-II intermittency within the framework of Horizontal Visibility graph theory. We construct graphs associated to time series generated by an iterated map close to a Neimark-Sacker bifurcation and study, both numerically and analytically, their main topological properties. We find well defined equivalences between the main statistical properties of intermittent series (scaling of laminar trends and Lyapunov exponent) and those of the resulting graphs, and accordingly construct a graph theoretical description of type-II intermittency. We finally recast this theory into a graph-theoretical renormalization group framework, and show that the fixed point structure of RG flow diagram separates regular, critical and chaotic dynamics.
description: 12 pages, 9 figures
Spectral gap characterizations of property (T) for II$_1$ factors
Creators: name: Tan, Hui
Publisher: name: arXiv
Year: 2022
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics

description: For II$_1$ factors, we show that property (T) is equivalent to weak spectral gap in any inclusion into a larger tracial von Neumann algebra. We also show that not having non-zero almost central vectors in weakly mixing bimodules characterizes property (T) for II$_1$ factors, which allows us to obtain a stronger characterization of property (T) where only weak spectral gap in any irreducible inclusion is required.
Mechanism of action of the trastuzumab biosimilar CT-P6
Creators: name: Jeong, Sun Ah
name: Choi, Jung Min
name: Park, Jun Mo
name: Lee, Jun Young
name: Lee, So Jung
name: Lee, Su Yeon
name: Lee, Si Yeon
name: Park, Yoon A
name: Jeong, Hee Jeong
name: Song, Yoo Cheol
name: Kim, Sung Hwan
name: Chang, Shin Jae
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Objectives: Therapeutic monoclonal antibody biosimilars are expected to help reduce the sizeable economic burden of targeted treatments. Trastuzumab (Herceptin®), a recombinant humanized monoclonal antibody that binds to the extracellular domain of HER2, is approved for use in HER2-overexpressing breast cancer (in both the adjuvant and metastatic settings) and HER2-positive gastric cancer. CT-P6 (Herzuma®) is a biosimilar of trastuzumab, designed to bind with high affinity and specificity to the same HER2 epitope as the reference product. We investigated whether CT-P6 exerts its effects through the same mechanism of action as trastuzumab. Methods: The mechanism of action of CT-P6 and trastuzumab, both as monotherapy and in combination with paclitaxel or pertuzumab, was compared in HER2-overexpressing breast cancer and gastric cancer cell models. Results: We confirmed that CT-P6 functions in a manner similar to trastuzumab by binding to the HER2 receptor, which is central to the effects of trastuzumab in all indications. Conclusions: Collectively, the results of this study show that the mechanisms of action of CT-P6 and trastuzumab are similar in HER2-positive breast cancer and gastric cancer models and, therefore, CT-P6 can be expected to perform similarly in the clinical setting.
Energy Loss of a Heavy Particle near 3D Charged Rotating Hairy Black Hole
Creators: name: Naji, Jalil
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we consider charged rotating black hole in 3 dimensions with an scalar charge and discuss about energy loss of heavy particle moving near the black hole horizon. We also study quasi-normal modes and find dispersion relations. We find that the effect of scalar charge and electric charge is increasing energy loss.
description: Accepted for publication in EPJC. arXiv admin note: text overlap with arXiv:1205.4254 by other authors
Scanning nano-SQUID with single electron spin sensitivity
Creators: name: Vasyukov, Denis
name: Anahory, Yonathan
name: Embon, Lior
name: Halbertal, Dorri
name: Cuppens, Jo
name: Ne'eman, Lior
name: Finkler, Amit
name: Segev, Yehonathan
name: Myasoedov, Yuri
name: Rappaport, Michael L.
name: Huber, Martin E.
name: Zeldov, Eli
Publisher: name: arXiv
Year: 2013
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: One of the critical milestones in the intensive pursuit of quantitative nanoscale magnetic imaging tools is achieving the level of sensitivity required for detecting the field generated by the spin magnetic moment μB of a single electron. Superconducting quantum interference devices (SQUIDs), which were traditionally the most sensitive magnetometers, could not hitherto reach this goal because of their relatively large effective size (of the order of 1 μm). Here we report self-aligned fabrication of nano-SQUIDs with diameters as small as 46 nm and with an extremely low flux noise of 50 nΦ0/Hz^1/2, representing almost two orders of magnitude improvement in spin sensitivity, down to 0.38 μB/Hz^1/2. In addition, the devices operate over a wide range of magnetic fields with 0.6 μB/Hz^1/2 sensitivity even at 1 T. We demonstrate magnetic imaging of vortices in type II superconductor that are 120 nm apart and scanning measurements of AC magnetic fields down to 50 nT. The unique geometry of these nano-SQUIDs that reside on the apex of a sharp tip allows approaching the sample to within a few nm, which paves the way to a new class of single-spin resolved scanning probe microscopy.
description: 10 pages, 9 figures (including supplementary material), Nature Nanotechnology in press
Conformal Submersions Whose Total Manifolds Admit a Ricci Soliton
Creators: name: Meena, Kiran
name: Yadav, Akhilesh
Publisher: name: arXiv
Year: 2022
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53B20, 53C12, 53C25, 53C43

description: In this paper, we study conformal submersions from Ricci solitons to Riemannian manifolds with non-trivial examples. First, we study some properties of the O'Neill tensor $A$ in the case of conformal submersion. We also find a necessary and sufficient condition for conformal submersion to be totally geodesic and calculate the Ricci tensor for the total manifold of such a map with different assumptions. Further, we consider a conformal submersion $F:M \to N$ from a Ricci soliton to a Riemannian manifold and obtain necessary conditions for the fibers of $F$ and the base manifold $N$ to be Ricci soliton, almost Ricci soliton and Einstein. Moreover, we find necessary conditions for a vector field and its horizontal lift to be conformal on $N$ and $(KerF_\ast)^\bot,$ respectively. Also, we calculate the scalar curvature of Ricci soliton $M$. Finally, we obtain a necessary and sufficient condition for $F$ to be harmonic.
Real dimensional spaces in noncommutative geometry
Creators: name: Jordans, Bas
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this paper we will extend the product of spectral triples to a product of semifinite spectral triples. We will prove that finite summability and regularity are preserved under taking products. Connes and Marcolli constructed for each $z\in(0,\infty)$ a type ${\rm II}_\infty$-semifinite spectral triple which can be considered as a geometric space of dimension $z$. A small adaption of their construction yields a type ${\rm I}$-semifinite spectral triple. We will investigate the properties of these semifinite spectral triples. At the same time we will also avoid the need for an infra-red cutoff to compute the dimension spectrum. Using this collection of semifinite spectral triples and the product of semifinite spectral triples one can construct a mathematical tool for dimensional and zeta-function regularisation in quantum field theory.
description: 29 pages, 2 figures
Population pharmacokinetics of PF-06438179/GP1111 (an infliximab biosimilar) and reference infliximab in patients with moderately to severely active rheumatoid arthritis
Creators: name: Palaparthy, Rameshraja
name: Rehman, Muhammad I.
name: von Richter, Oliver
name: Yin, Donghua
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences

description: Background: PF-06438179/GP1111 (PF-SZ-IFX) is an infliximab (IFX) biosimilar.
 Pharmacokinetic (PK) similarity of PF-SZ-IFX and reference IFX authorized in the European Union
 (ref-IFX-EU) and in the US (ref-IFX-US) was demonstrated in healthy subjects. Safety and
 efficacy of PF-SZ-IFX were investigated in a multinational, double-blind, randomized study in
 rheumatoid arthritis (RA) patients. This work aims to evaluate the population pharmacokinetics
 (PopPK) of ref-IFX-EU and PF-SZ-IFX in RA patients. Research design and methods: Patients with moderately to severely active RA (N =
 650) were randomized 1:1 to PF-SZ-IFX or ref-IFX-EU. PopPK modeling with data collected from
 the study was performed using a nonlinear mixed-effects approach (NONMEM 7.2.0). Results: The PK of ref-IFX-EU and PF-SZ-IFX were adequately described using a
 two-compartment model with linear elimination. Clearance (CL) estimates were 0.014 L/h and
 0.015 L/h for PF-SZ-IFX and ref-IFX-EU, with inter-individual variability (IIV) on CL of 43.1%
 and 40.1%, respectively. Volumes of distribution in the central compartment (V1)
 were 3.38 L and 3.57 L, with IIV on V1 of 28.1% and 23.7%, respectively. The same
 covariates of sex and antidrug antibody titers on CL, and body weight on V1,
 influenced the PK variability of ref-IFX-EU and PF-SZ-IFX. Conclusions: PopPK analysis revealed no appreciable differences between the PK
 of ref-IFX-EU and PF-SZ-IFX in RA patients. Trial registration:ClinicalTrials.gov identifier: NCT02222493.
Discovering a 5.72 Day Period in the Supergiant Fast X-ray Transient AX J1845.0-0433
Creators: name: Goossens, M. E.
name: Bird, A. J.
name: Drave, S. P.
name: Bazzano, A.
name: Hill, A. B.
name: McBride, V. A.
name: Sguera, V.
name: Sidoli, L.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Temporal analysis of INTEGRAL/IBIS data has revealed a 5.7195\pm0.0007 day periodicity in the supergiant fast X-ray transient (SFXT) source AX J1845.0-0433, which we interpret as the orbital period of the system. The new-found knowledge of the orbital period is utilised to investigate the geometry of the system by means of estimating an upper limit for the size of the supergiant (<27 R_{\sun}) as well as the eccentricity of the orbit (ε<0.37).
description: 6 pages, 6 figures, accepted for publication in MNRAS
Varying-coefficients for regional quantile via KNN-based LASSO with applications to health outcome study
Creators: name: Park, Seyoung
name: Lee, Eun Ryung
name: Hong, Hyokyoung G.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Health outcomes, such as body mass index and cholesterol levels, are known to be dependent on age and exhibit varying effects with their associated risk factors. In this paper, we propose a novel framework for dynamic modeling of the associations between health outcomes and risk factors using varying-coefficients (VC) regional quantile regression via K-nearest neighbors (KNN) fused Lasso, which captures the time-varying effects of age. The proposed method has strong theoretical properties, including a tight estimation error bound and the ability to detect exact clustered patterns under certain regularity conditions. To efficiently solve the resulting optimization problem, we develop an alternating direction method of multipliers (ADMM) algorithm. Our empirical results demonstrate the efficacy of the proposed method in capturing the complex age-dependent associations between health outcomes and their risk factors.
Population pharmacokinetics of PF-06438179/GP1111 (an infliximab biosimilar) and reference infliximab in patients with moderately to severely active rheumatoid arthritis
Creators: name: Palaparthy, Rameshraja
name: Rehman, Muhammad I.
name: von Richter, Oliver
name: Yin, Donghua
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences

description: Background: PF-06438179/GP1111 (PF-SZ-IFX) is an infliximab (IFX) biosimilar. Pharmacokinetic (PK) similarity of PF-SZ-IFX and reference IFX authorized in the European Union (ref-IFX-EU) and in the US (ref-IFX-US) was demonstrated in healthy subjects. Safety and efficacy of PF-SZ-IFX were investigated in a multinational, double-blind, randomized study in rheumatoid arthritis (RA) patients. This work aims to evaluate the population pharmacokinetics (PopPK) of ref-IFX-EU and PF-SZ-IFX in RA patients. Research design and methods: Patients with moderately to severely active RA (N = 650) were randomized 1:1 to PF-SZ-IFX or ref-IFX-EU. PopPK modeling with data collected from the study was performed using a nonlinear mixed-effects approach (NONMEM 7.2.0). Results: The PK of ref-IFX-EU and PF-SZ-IFX were adequately described using a two-compartment model with linear elimination. Clearance (CL) estimates were 0.014 L/h and 0.015 L/h for PF-SZ-IFX and ref-IFX-EU, with inter-individual variability (IIV) on CL of 43.1% and 40.1%, respectively. Volumes of distribution in the central compartment (V1) were 3.38 L and 3.57 L, with IIV on V1 of 28.1% and 23.7%, respectively. The same covariates of sex and antidrug antibody titers on CL, and body weight on V1, influenced the PK variability of ref-IFX-EU and PF-SZ-IFX. Conclusions: PopPK analysis revealed no appreciable differences between the PK of ref-IFX-EU and PF-SZ-IFX in RA patients. Trial registration: The trial is registered at ClinicalTrials.gov (CT.gov identifier: NCT02222493).
A Pedestrian Approach to the Measurement Problem in Quantum Mechanics
Creators: name: Boughn, Stephen
name: Reginatto, Marcel
Publisher: name: arXiv
Year: 2013
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The quantum theory of measurement has been a matter of debate for over eighty years. Most of the discussion has focused on theoretical issues with the consequence that operational prescriptions, which are integral to experimental physics, have been largely ignored. This has undoubtedly exacerbated attempts to find a solution to the "measurement problem". In this paper, we fully embrace the ensemble interpretation of quantum mechanics that obviates the need to entertain reduction of the state vector, one of the primary dilemmas of the measurement problem. The other major aspect of the measurement problem, the necessity of describing measurements in terms of classical concepts, remains. However, we argue that the ultimate interface with experiments is described by operational prescriptions and not in terms of the concepts of classical theory. The pedestrian approach presented here suggests that the measurement problem is, in some sense, ill-posed and might never be resolved. This state of affairs is, in part, the result of searching for a theoretical answer to what is fundamentally an experimental question. This point of view is tenable so long as one is willing to view physical theories as providing models of nature rather than complete descriptions of reality. Among other things, these considerations lead us to suggest that the Copenhagen interpretation's insistence on the classicality of the measurement apparatus should be replaced by the requirement that a measurement, which is specified operationally, should simply be of sufficient precision.
Reflecting Brownian motion in generalized parabolic domains: explosion and superdiffusivity
Creators: name: Menshikov, Mikhail V.
name: Mijatović, Aleksandar
name: Wade, Andrew R.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J60 (Primary) 60J55, 60J65, 60F15, 60K50 (Secondary)

description: For a multidimensional driftless diffusion in an unbounded, smooth, sub-linear generalized parabolic domain, with oblique reflection from the boundary, we give natural conditions under which either explosion occurs, if the domain narrows sufficiently fast at infinity, or else there is superdiffusive transience, which we quantify with a strong law of large numbers. For example, in the case of a planar domain, explosion occurs if and only if the area of the domain is finite. We develop and apply novel semimartingale criteria for studying explosions and establishing strong laws, which are of independent interest.
description: 39 pages, 2 figures
MPEC 2023-E61 : 2023 EO
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 EO

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
The Importance of the Historic Pilgrimage Monuments in Urban Spaces of Iran.pdf
Creators: name: Kheiri, Ali
name: Zahedeh Mammadova
Publisher: name: figshare
Year: 2019
Subjects: subject: 120103 Architectural History and Theory
subject: FOS: Civil engineering
subject: 120102 Architectural Heritage and Conservation
subject: 120104 Architectural Science and Technology (incl. Acoustics, Lighting, Structure and Ecologically Sustainable Design)
subject: 120105 Architecture Management
subject: 120507 Urban Analysis and Development
subject: FOS: Social and economic geography
subject: 120508 Urban Design
subject: 120599 Urban and Regional Planning not elsewhere classified
subject: 120199 Architecture not elsewhere classified
subject: 120502 History and Theory of the Built Environment (excl. Architecture)

description: Iran in terms of architectural culture - urbanization and the wealth of its valuable historical works, without a doubt, is one of world's most significant countries, works that must be very well maintained. One of the major issues in current architecture and urbanization of a country is the preservation of its urban spaces and ancient historical architecture and the different viewpoints on how to preserve these spaces and valuable old buildings. Since these works represent the historical identity of their own time, we should diligently preserve and protect these structures as symbols of national culture and the bond between yesterday, today and the future generations. In this study, which is based on archival and fieldwork research, the role and importance of pilgrimage mausoleums, and the physical changes resulting from their repair or restoration on shaping the urban spaces will be examined and evaluated.
"HEPData_workspaces.tar.gz" of "Search for bottom-squark pair production with the ATLAS detector in final states containing Higgs bosons, $b$-jets and missing transverse momentum"
Creators: name: ATLAS Collaboration
Publisher: name: HEPData
Year: 2019

description: Archive of full likelihoods in the HistFactory JSON format described in ATL-PHYS-PUB-2019-029 Provided are 3 statiscal models labeled RegionA RegionB and RegionC respectively each in their own sub-directory. For each model the background-only model is found i the file named 'BkgOnly.json' For each model a set of patches for various signal points is provided
description: No data abstract available.
Imaging Atomic-Scale Chemistry from Fused Multi-Modal Electron Microscopy
Creators: name: Schwartz, Jonathan
name: Di, Zichao Wendy
name: Jiang, Yi
name: Fielitz, Alyssa J.
name: Ha, Don-Hyung
name: Perera, Sanjaya D.
name: Baggari, Ismail El
name: Robinson, Richard D.
name: Fessler, Jeffrey A.
name: Ophus, Colin
name: Rozeveld, Steve
name: Hovden, Robert
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Efforts to map atomic-scale chemistry at low doses with minimal noise using electron microscopes are fundamentally limited by inelastic interactions. Here, fused multi-modal electron microscopy offers high signal-to-noise ratio (SNR) recovery of material chemistry at nano- and atomic- resolution by coupling correlated information encoded within both elastic scattering (high-angle annular dark field (HAADF)) and inelastic spectroscopic signals (electron energy loss (EELS) or energy-dispersive x-ray (EDX)). By linking these simultaneously acquired signals, or modalities, the chemical distribution within nanomaterials can be imaged at significantly lower doses with existing detector hardware. In many cases, the dose requirements can be reduced by over one order of magnitude. This high SNR recovery of chemistry is tested against simulated and experimental atomic resolution data of heterogeneous nanomaterials.
Evolution of electron-boson spectral density in the underdoped region of Bi_2Sr_{2-x}La_xCuO_6
Creators: name: Hwang, Jungseek
name: Carbotte, J. P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We use a maximum entropy technique to obtain the electron-boson spectral density from optical scattering rate data across the underdoped region of the Bi_2Sr_{2-x}La_xCuO_6 (Bi-2201) phase diagram. Our method involves a generalization of previous work which explicitly include finite temperature and the opening of a pseudogap which modifies the electronic structure. We find that the mass enhancement factor λassociated with the electron-boson spectral density increases monotonically with reduced doping and closer proximity to the Mott antiferromagnetic insulating state. This observation is consistent with increased coupling to the spin fluctuations. At the same time the system has reduced metallicity because of increased pseudogap effects which we model with a reduced effective density of states around the Fermi energy with the range of the modifications in energy set by the pseudogap scale.
description: 14 pages, 5 figures
MPEC 2023-E62 : 2023 EP
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 EP

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Electromagnetic transitions among octet and decuplet baryons in QCD
Creators: name: Aliev, T. M.
name: Oktem, Y.
name: Savci, M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The magnetic dipole G_M(Q^2), electric quadrupole G_E(Q^2), and Coulomb quadrupole G_C(Q^2) form factors, describing the spin-3/2 to spin-1/2 electromagnetic transitions, are investigated within the light cone QCD sum rules. The Q^2 dependence of these form factors, as well as ratios of electric quadrupole and Coulomb quadrupole form factors to the magnetic dipole form factors are studied. We also compare our results on the magnetic dipole form factor with the prediction of the covariant spectator quark model.
description: 20 pages, 10 figures, LaTeX formatted
Dynamics of Vapor Layer Under a Leidenfrost Drop
Creators: name: Caswell, Thomas A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In the Leidenfrost effect a small drop of fluid is levitated above a sufficiently hot surface, on a persistent vapor layer generated by evaporation from the drop. The vapor layer thermally insulates the drop from the surface leading to extraordinarily long drop lifetimes. The top-view shape of the levitated drops can exhibit persistent star-like vibrations. I extend recent work [Burton et al. PRL 2012] to study the bottom surface of the drop using interference-imaging. In this work I use a high-speed camera and automated image analysis to image, locate and classify the interference fringes. From the interference fringes I reconstruct the shape and height profile of the rim where the drop is closest to the surface. I measure the drop-size dependence of the planar vibrational mode frequencies, which agree well with previous work. I observe a distinct breathing mode in the average radius of the drop, the frequency of which scales differently with drop size than the other modes. This breathing mode can be tightly coupled to a vertical motion of the drop. I further observe a qualitative difference in the structure and dynamics of the vertical profile of the rim between large and small drops.
description: 11 pages, 12 figures, University of Chicago PhD Thesis
Migration and gas accretion scenarios for the Kepler 16, 34 and 35 circumbinary planets
Creators: name: Pierens, Arnaud
name: Nelson, Richard P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Several circumbinary planets have been detected by the Kepler mission. Recent work has emphasized the difficulty of forming these planets at their observed locations. It has been suggested that these planets formed further out in their discs and migrated in to locations where they are observed. We examine the orbital evolution of planets embedded in circumbinary disc models for the three systems Kepler-16, Kepler-34 and Kepler-35. The aims are: to explore the plausibility of a formation scenario in which cores form at large distances from the binaries and undergo inward migration and gas accretion as the gas disc disperses; to determine which sets of disc parameters lead to planets whose final orbits provide reasonable fits to the observed systems. We performed simulations of a close binary system interacting with circumbinary discs with differing aspect ratios, and viscous stress parameters. Once the binary+disc system reaches quasi-equilibrium we embed a planet in the disc and examine its evolution under the action of binary and disc forces. We consider fully-formed planets with masses equal to those inferred from Kepler data, and low-mass cores that migrate and accrete gas while the gas disc is being dispersed. A typical outcome for all systems is stalling of inward migration as the planet enters the inner cavity formed by the binary system. The circumbinary disc becomes eccentric and the disc eccentricity forces the planet into a noncircular orbit. For each of the Kepler-16b, Kepler-34b and Kepler-35b systems we obtain planets whose parameters agree reasonably well with the observational data. The simulations presented here provide support for a formation scenario in which a core forms, migrates inward and accretes gas, but accurate fitting of the observed Kepler systems is likely to require disc models that are significantly more sophisticated in terms of their input physics.
description: Accepted for publication in A&A
On the Hardness of the Minimum Distance Problem of Quantum Codes
Creators: name: Kapshikar, Upendra
name: Kundu, Srijita
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Discrete Mathematics (cs.DM)
subject: Combinatorics (math.CO)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: We study the hardness of the problem of finding the distance of quantum error-correcting codes. The analogous problem for classical codes is known to be NP-hard, even in approximate form. For quantum codes, various problems related to decoding are known to be NP-hard, but the hardness of the distance problem has not been studied before. In this work, we show that finding the minimum distance of stabilizer quantum codes exactly or approximately is NP-hard. This result is obtained by reducing the classical minimum distance problem to the quantum problem, using the CWS framework for quantum codes, which constructs a quantum code using a classical code and a graph. A main technical tool used for our result is a lower bound on the so-called graph state distance of 4-cycle free graphs. In particular, we show that for a 4-cycle free graph $G$, its graph state distance is either $δ$ or $δ+1$, where $δ$ is the minimum vertex degree of $G$. Due to a well-known reduction from stabilizer codes to CSS codes, our results also imply that finding the minimum distance of CSS codes is also NP-hard.
description: Contains results previously included in arXiv:2107.11286
"SbMB_SLHAs.tar.gz" of "Search for bottom-squark pair production with the ATLAS detector in final states containing Higgs bosons, $b$-jets and missing transverse momentum"
Creators: name: ATLAS Collaboration
Publisher: name: HEPData
Year: 2019

description: slha files for the 3 baseline signal points used in the analysis for regions A,B,C
description: No data abstract available.
MPEC 2023-E63 : 2023 EQ
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 EQ

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Will your Doorbell Camera still recognize you as you grow old
Creators: name: Yao, Wang
name: Farooq, Muhammad Ali
name: Lemley, Joseph
name: Corcoran, Peter
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Robust authentication for low-power consumer devices such as doorbell cameras poses a valuable and unique challenge. This work explores the effect of age and aging on the performance of facial authentication methods. Two public age datasets, AgeDB and Morph-II have been used as baselines in this work. A photo-realistic age transformation method has been employed to augment a set of high-quality facial images with various age effects. Then the effect of these synthetic aging data on the high-performance deep-learning-based face recognition model is quantified by using various metrics including Receiver Operating Characteristic (ROC) curves and match score distributions. Experimental results demonstrate that long-term age effects are still a significant challenge for the state-of-the-art facial authentication method.
description: The Paper is accepted in 25th Irish Machine Vision and Image Processing Conference (IMVIP23)
Using the Random Sprays Retinex Algorithm for Global Illumination Estimation
Creators: name: Banić, Nikola
name: Lončarić, Sven
Publisher: name: arXiv
Year: 2013
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this paper the use of Random Sprays Retinex (RSR) algorithm for global illumination estimation is proposed and its feasibility tested. Like other algorithms based on the Retinex model, RSR also provides local illumination estimation and brightness adjustment for each pixel and it is faster than other path-wise Retinex algorithms. As the assumption of the uniform illumination holds in many cases, it should be possible to use the mean of local illumination estimations of RSR as a global illumination estimation for images with (assumed) uniform illumination allowing also the accuracy to be easily measured. Therefore we propose a method for estimating global illumination estimation based on local RSR results. To our best knowledge this is the first time that RSR algorithm is used to obtain global illumination estimation. For our tests we use a publicly available color constancy image database for testing. The results are presented and discussed and it turns out that the proposed method outperforms many existing unsupervised color constancy algorithms. The source code is available at http://www.fer.unizg.hr/ipg/resources/color_constancy/.
description: Part of the Proceedings of the Croatian Computer Vision Workshop, CCVW 2013, Year 1
Switching transformations for decentralized control of opinion patterns in signed networks: application to dynamic task allocation
Creators: name: Bizyaeva, Anastasia
name: Amorim, Giovanna
name: Santos, Maria
name: Franci, Alessio
name: Leonard, Naomi Ehrich
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optimization and Control (math.OC)
subject: Systems and Control (eess.SY)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: We propose a new decentralized design method to control opinion patterns on signed networks of agents making decisions about two options and to switch the network from any opinion pattern to a new desired one. Our method relies on switching transformations, which switch the sign of an agent's opinion at a stable equilibrium by flipping the sign of its local interactions with its neighbors. The global dynamical behavior of the switched network can be predicted rigorously when the original, and thus the witched, networks are structurally balanced. Structural balance ensures that the network dynamics are monotone, which makes the study of the basin of attraction of the various opinion patterns amenable to rigorous analysis through monotone systems theory. We illustrate the utility of the approach through scenarios motivated by multi-robot coordination and dynamic task allocation.