Is Hidradenitis Suppurativa associated with a lower socioeconomic status compared to the general population: A systematic review and meta-analysis.
Creators: name: Bailey, Adrian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Diseases
subject: Public Health
subject: Medicine and Health Sciences

description: 1. * Review title. Is Hidradenitis Suppurativa associated with a lower socioeconomic status compared to the general population: A systematic review and meta-analysis. 2. * Anticipated or actual start date. 05/02/2020 3. * Anticipated completion date. 07/04/2020 4. * Stage of review at time of this submission. Review stage Started Completed Preliminary searches Completed Piloting of the study selection process Completed Formal screening of search results against eligibility criteria Completed 5. * Named contact. Adrian Bailey 6. * Named contact email. abail082@uottawa.ca 7. Named contact address 4512 Appleton Side Road 8. Named contact phone number. 6138585029 9. * Organisational affiliation of the review. University of Ottawa 10. * Funding sources/sponsors. None 11. * Conflicts of interest. None 12. * Review question. Is Hidradenitis Suppurativa associated with a lower socioeconomic status compared to the general population? P = Adult patients with Hidradenitis Suppurativa I = N/A C = The general adult population (or a reference population that is representative of the general population) O = Socioeconomic status 13. * Searches. PubMed and Scopus (April 3rd 2020). No date restrictions. English articles only. 14. * Condition or domain being studied. Low socioeconomic status (SES) has been shown to be associated with hidradenitis suppurativa (HS); however, the literature lacks an assessment of this association across a variety of populations and recommendations for future research. Here, we plan toi systematically review and meta-analyse the current evidence on HS and SES. 15. * Participants/population. Inclusion: -Adult patients (16 years or older) with Hidradenitis Suppurativa Exclusion: -Paediatric patients -Animal studies 16. * Intervention(s), exposure(s). -Not applicable. 17. * Comparator(s)/control. -General population (ex. other dermatology patients) 18. * Types of study to be included. Eligible study designs included population-based retrospective cohort, cross sectional, and case-control studies. Grey literature and other study designs were excluded. An Odds ratio will be used to measure the association between low socioeconomic status and patients with Hidradenitis Suppurativa compared to a reference population (a representative sample of the general population). Studies that do not provide this data, data necessary to calculate an Odds ratio, or their corresponding author was not able to provide this data will be excluded. 19. * Main outcome(s). -Socioeconomic status. Any definition and stratification of SES will be accepted, such as income, postal code, occupation, insurance status, and census data. * Measures of effect -An Odds ratio will be used to measure the association between low socioeconomic status and patients with Hidradenitis Suppurativa compared to a reference population. 20. * Data extraction (selection and coding). -Study Characteristics = setting, date range of data collection, population size, socioeconomic status measure used, if an adjusted model was used, and what factors were accounted for if an adjusted model was used. -Odds ratio or raw data that can be used to calculate the Odds ratio of the association of low socioeconomic status and patients with Hidradenitis Suppurativa, compared to a reference population. 21. * Risk of bias (quality) assessment. The risk of bias will be determined using the National Institutes of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. 22. * Strategy for data synthesis. The inverse variance model with the fixed effects model, to account for variations in study size, will be used to estimate the Odds ratio and confidence intervals for each study. Heterogeneity across studies will be assessed using the I² statistic. 23. * Analysis of subgroups or subsets. None planned 24. Language. English 25. * Country. Canada 26. Dissemination plans. Publication to a major journal. 27. Current review status. Ongoing.