cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Characterization of the Escherichia coli F factor traY gene product and its binding sites.
Creators: name: Nelson, W C
name: Morton, B S
name: Lahue, E E
name: Matson, S W
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: The traY gene product (TraYp) from the Escherichia coli F factor has previously been purified and shown to bind a DNA fragment containing the F plasmid oriT region (E. E. Lahue and S. W. Matson, J. Bacteriol. 172:1385-1391, 1990). To determine the precise nucleotide sequence bound by TraYp, DNase I footprinting was performed. The TraYp-binding site is near, but not coincident with, the site that is nicked to initiate conjugative DNA transfer. In addition, a second TraYp binding site, which is coincident with the mRNA start site at the traYI promoter, is described. The Kd for each binding site was determined by a gel mobility shift assay. TraYp exhibits a fivefold higher affinity for the oriT binding site compared with the traYI promoter binding site. Hydrodynamic studies were performed to show that TraYp is a monomer in solution under the conditions used in DNA binding assays. Early genetic experiments implicated the traY gene product in the site- and strand-specific endonuclease activity that nicks at oriT (R. Everett and N. Willetts, J. Mol. Biol. 136:129-150, 1980; S. McIntire and N. Willetts, Mol. Gen. Genet. 178:165-172, 1980). As this activity has recently been ascribed to helicase I, it was of interest to see whether TraYp had any effect on this reaction. Addition of TraYp to nicking reactions catalyzed by helicase I showed no effect on the rate or efficiency of oriT nicking. Roles for TraYp in conjugative DNA transfer and a possible mode of binding to DNA are discussed.
Towards a Model of Quarks and Leptons
Creators: name: Ahn, Y. H.
name: Kang, Sin Kyu
name: Lee, Hyun Min
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose an extra-dimension framework on the orbifold $S^1/Z_2$ for understanding the origin of the fermion mass and mixing hierarchies. Introducing the flavor symmetry $G_F(=${\it non-Abelian}$\times${\it Abelian}) as well as the extra gauged $U(1)$ symmetries through the bulk, we regard the $SU(2)$ singlet and doublet fermions in the Standard Model (SM) to be localized at the separate 3-branes and let the extra $SU(2)$ singlet flavored fermions in the bulk couple to the SM fermions at the 3-branes. The extra $U(1)$ symmetries satisfy the $U(1)$ gravitational anomaly-free condition, playing a crucial role in achieving the desirable fermion mass and mixing hierarchies and making the flavored axion naturally light. The singlet scalar fields, the flavon fields, are responsible for the spontaneous breaking of $G_F$ on the two 3-branes, while the $SU(2)$ singlet flavored fermions are integrated out to give rise to the effective Yukawa couplings for the SM fermions, endowed with the information of $G_F$ breaking in the two sectors. The flavored axion from the PQ symmetry is also proposed for solving the strong CP problem and being a dark matter candidate in our model.
description: 7 pages, 3 figures
Approximate spectral clustering density-based similarity for noisy datasets
Creators: name: Alshammari, Mashaan
name: Takatsuka, Masahiro
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Information Retrieval (cs.IR)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Approximate spectral clustering (ASC) was developed to overcome heavy computational demands of spectral clustering (SC). It maintains SC ability in predicting non-convex clusters. Since it involves a preprocessing step, ASC defines new similarity measures to assign weights on graph edges. Connectivity matrix (CONN) is an efficient similarity measure to construct graphs for ASC. It defines the weight between two vertices as the number of points assigned to them during vector quantization training. However, this relationship is undirected, where it is not clear which of the vertices is contributing more to that edge. Also, CONN could be tricked by noisy density between clusters. We defined a directed version of CONN, named DCONN, to get insights on vertices contributions to edges. Also, we provided filtering schemes to ensure CONN edges are highlighting potential clusters. Experiments reveal that the proposed filtering was highly efficient when noise cannot be tolerated by CONN.
Rejoinder of "Instrumental Variables: An Econometrician's Perspective"
Creators: name: Imbens, Guido
Publisher: name: arXiv
Year: 2014
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Rejoinder of "Instrumental Variables: An Econometrician's Perspective" by Guido W. Imbens [arXiv:1410.0163].
description: Published in at http://dx.doi.org/10.1214/14-STS496 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Supplementary document for On-chip Ultracompact Multimode Vortex Beam Emitter Based on Vertical Modes - 6054031.pdf
Creators: name: Wei, Zeyong
name: Li, Shuqiao
name: Xie, Lingyun
name: deng, xiao
name: Wang, Zhanshan
name: Cheng, Xinbin
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Supplement 1
К вопросу о территориальных спорах Китая
Creators: name: Васильев Леонид Евгеньевич
Publisher: name: Китай в мировой и региональной политике. История и современность
Year: 2017
Subjects: КИТАЙСКАЯ НАРОДНАЯ РЕСПУБЛИКА
ИНДИЯ
ГОСУДАРСТВА АСЕАН
РЕГИОНАЛЬНАЯ БЕЗОПАСНОСТЬ
МЕЖГОСУДАРСТВЕННЫЕ ОТНОШЕНИЯ В АЗИИ
ТЕРРИТОРИАЛЬНЫЕ КОНФЛИКТЫ

description: Статья посвящена анализу состояния межгосударственных отношений Китая с государствами Азии, с которыми у него имеются взаимные территориальные претензии. В статье представлена суть территориальных противоречий, проанализированы способы их решения в настоящее время, а также сделан прогноз разрешения ситуации в ближайшей перспективе.
Study of hadron interactions in a lead-emulsion target
Creators: name: Ishida, Hirokazu
name: Fukuda, Tsutomu
name: Kajiwara, Takafumi
name: Kodama, Koichi
name: Komatsu, Masahiro
name: Matsuo, Tomokazu
name: Mikado, Shoji
name: Nakamura, Mitsuhiro
name: Ogawa, Satoru
name: Sheshukov, Andrey
name: Shibuya, Hiroshi
name: Sudou, Jun
name: Suzuki, Taira
name: Tsuchida, Yusuke
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Topological and kinematical characteristics of hadron interactions have been studied using a lead-emulsion target exposed to 2, 4 and 10 GeV/c hadron beams. A total length of 60 m $π^-$ tracks was followed using a high speed automated emulsion scanning system. A total of 318 hadron interaction vertices and their secondary charged particle tracks were reconstructed. Measurement results of interaction lengths, charged particle multiplicity, emission angles and momenta of secondary charged particles are compared with a Monte Carlo simulation and appear to be consistent. Nuclear fragments emitted from interaction vertices were also detected by a newly developed emulsion scanning system with wide-angle acceptance. Their emission angle distributions are in good agreement with the simulated distributions. Probabilities of an event being associated with at least one fragment track are found to be greater than 50% for beam momentum $P > 4$ GeV/c and are well reproduced by the simulation. These experimental results validate estimation of the background due to hadron interactions in the sample of $τ$ decay candidates in the OPERA $ν_μ \to ν_τ$ oscillation experiment.
description: 14 pages, 11 figures
title: Wybrane problemy związane z korzystaniem z cudzej twórczości naukowej i dydaktycznej na tle uregulowania prawa autorskiego, dotyczącego wypisów, antologii i prawa cytowania
Creators: name: Jezioro, Julian
Publisher: name: E-Wydawnictwo. Prawnicza i Ekonomiczna Biblioteka Cyfrowa. Wydział Prawa, Administracji i Ekonomii Uniwersytetu Wrocławskiego
Year: 2020

description: Autor, analizując ogólne założenia monografii poświęconej znaczeniu twórczości naukowej Profesora Tadeusza Bigi w działalności innych autorów tworzących administratywistyczną szkołę wrocławską, omawiając wybrane przepisy ustawy z 4 lutego 1994 r. o prawie autorskim i prawach pokrewnych, stawia i stara się uzasadnić tezę, że polskie prawo autorskie nie systematyzuje bezpośrednio sytuacji utworów, które posiadają łącznie zarówno cechy wypisów, jak i opracowań samodzielnych, w których cudza twórczość wykorzystywana jest w ramach prawa cytowania. Podejmuje też próbę sformułowania ogólnych przesłanek umożliwiających ocenę legalizacji takiego korzystania z cudzej twórczości. Uzasadnieniem dla podjęcia się takiej analizy jest waga sytuacji, w których całościowy wkład określonego twórcy-naukowca ma znaczenie, które można określić jako „fundamentalne” dla wielu wykorzystujących go twórców-następców, którzy w swojej twórczości odwołują się do niego jako do efektów działalności swojego „mistrza”.
К итогам нормализации китайско-норвежских отношений
Creators: name: Криворотов Андрей Константинович
name: Виноградов Андрей Олегович
Publisher: name: Китай в мировой и региональной политике. История и современность
Year: 2017
Subjects: НОРВЕГИЯ
КНР
ДИПЛОМАТИЧЕСКИЙ КРИЗИС
УРЕГУЛИРОВАНИЕ
ЭКОНОМИЧЕСКОЕ СОТРУДНИЧЕСТВО
АРКТИКА
ОЦЕНКИ

description: В статье рассматривается урегулирование кризиса 2010-2016 гг. в отношениях КНР и Норвегии, возникшего после присуждения Нобелевской премии мира китайскому диссиденту Лю Сяобо. Взаимное доверие была восстановлено, прежде всего, путем закрытых дипломатических переговоров. При этом Норвегия подверглась серьезному давлению Китая, который с успехом устанавливает новый типсотрудничества с зарубежными странами, не приемлющий вмешательства в его широко понятые коренные интересы.
Some mathematical aspects of Anderson localization: boundary effect, multimodality, and bifurcation
Creators: name: Jia, Chen
name: Liu, Ziqi
name: Zhang, Zhimin
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 35J10, 35J25, 82B44, 47A75, 35Q40

description: Anderson localization is a famous wave phenomenon that describes the absence of diffusion of waves in a disordered medium. Here we generalize the landscape theory of Anderson localization to general elliptic operators and complex boundary conditions using a probabilistic approach, and further investigate some mathematical aspects of Anderson localization that are rarely discussed before. First, we observe that under the Neumann boundary condition, the low energy quantum states are localized on the boundary of the domain with high probability. We provide a detailed explanation of this phenomenon using the concept of extended subregions and obtain an analytical expression of this probability in the one-dimensional case. Second, we find that the quantum states may be localized in multiple different subregions with high probability in the one-dimensional case and we derive an explicit expression of this probability for various boundary conditions. Finally, we examine a bifurcation phenomenon of the localization subregion as the strength of disorder varies. The critical threshold of bifurcation is analytically computed based on a toy model and the dependence of the critical threshold on model parameters is analyzed.
description: 31 pages, 7 figures
Китайская политика помощи зарубежным странам: основные принципы и направления
Creators: name: Кашин Василий Борисович
name: Королев Александр Сергеевич
name: Пятачкова Анастасия Сергеевна
Publisher: name: Китай в мировой и региональной политике. История и современность
Year: 2017
Subjects: ЗАРУБЕЖНАЯ ПОМОЩЬ
КИТАЙ
АФРИКА
ЮГО-ВОСТОЧНАЯ АЗИЯ
РОССИЯ

description: В статье анализируются концептуальные основы китайской помощи внешнему миру, проводится оценка ее эффективности на примере стран Африки и Юго-Восточной Азии как главных реципиентов китайского содействия. Также в статье приводятся рекомендации по использованию Россией соответствующего опыта Китая в целях улучшения имиджа РФ как страны-донора.
The Degree of Quantum Contextuality in terms of Concurrence for the KCBS Scenario
Creators: name: Diker, Firat
name: Gedik, Zafer
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum contextuality is the key concept which explains the fact that the result of a measurement is not independent of the context in which it is found. It is observed to be an intrinsic feature, i.e., neither entanglement nor spatial separation is required. In this work, we revisit the previous studies which state that entanglement is an intrinsic property called self-entanglement. Using this fact, we explicitly show the correlation between quantum contextuality and concurrence in the KCBS scenario, which is the simplest approach to observing contextuality. We also derive the equation for the maximal violation of the KCBS scenario for a given concurrence and find the linear relation between them. Using this relation, we also show how the maximal violations of the KCBS and CHSH inequalities are related for an arbitrary entanglement. Moreover, we discuss the special cases of maximal entanglement, and non-entanglement for which we have found a lower local bound.
description: The final publication is available at Springer via https://doi.org/10.1007/s10773-022-05245-0
Brownian motion and gambling: from ratchets to paradoxical games
Creators: name: Parrondo, J. M. R.
name: Dinis, L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computer Science and Game Theory (cs.GT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Two losing gambling games, when alternated in a periodic or random fashion, can produce a winning game. This paradox has been inspired by certain physical systems capable of rectifying fluctuations: the so-called Brownian ratchets. In this paper we review this paradox, from Brownian ratchets to the most recent studies on collective games, providing some intuitive explanations of the unexpected phenomena that we will find along the way.
description: 25 pages, 11 figures
Thermodynamics of Einstein-Aether Black Holes
Creators: name: Chan, R.
name: da Silva, M. F. A.
name: Satheeshkumar, V. H.
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We analyze several spherically symmetric exterior vacuum solutions allowed by the Einstein-Aether (EA) theory with a non static aether and study the thermodynamics of their Killing and universal horizons. We show that there are five classes of solutions corresponding to different values of a combination of the free parameters, $c_{2}$, $c_{13}=c_1+c_3$ and $c_{14}=c_1+c_4$, which are: (A) $c_2 \ne 0$ and $c_{13} \ne 0$ and $c_{14}=0$, (B) $c_2 \ne 0$ and $c_{13} = 0$ and $c_{14} = 0$, (C) $c_2 = 0$ and $c_{13} \ne 0$ and $c_{14} = 0$, (D) $c_2 = 0$, $c_{13} = 0$ and $c_{14} \ne 0$, and (E) $c_2 = - c_{13} \ne 0$ and $c_{14} \ne 0$. We present explicit analytical solutions for these five cases. All these cases have singularities at $r=0$ and are asymptotically flat spacetimes and possess both Killing and universal horizons with the universal horizons always being inside the Killing horizons. Finally, we compute the surface gravity, the temperature, the entropy and the first law of thermodynamics for the universal horizons.
description: 35 pages, 5 figures and 4 tables. We have improved the manuscript with a new solution and a comparison with others authors who have used Eddington-Finkelstein coordinates
Characterization of the reaction product of the oriT nicking reaction catalyzed by Escherichia coli DNA helicase I.
Creators: name: Nelson, W C
name: Morton, B S
name: Matson, S W
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: DNA helicase I, encoded on the Escherichia coli F plasmid, catalyzes a site- and strand-specific nicking reaction within the F plasmid origin of transfer (oriT) to initiate conjugative DNA strand transfer. The product of the nicking reaction contains a single phosphodiester bond interruption as determined by single-nucleotide resolution mapping of both sides of the nick site. This analysis has demonstrated that the nick is located at precisely the same site previously shown to be nicked in vivo (T. L. Thompson, M. B. Centola, and R. C. Deonier, J. Mol. Biol. 207:505-512, 1989). In addition, studies with two oriT point mutants have confirmed the specificity of the in vitro reaction. Characterization of the nicked DNA product has revealed a modified 5' end and a 3' OH available for extension by E. coli DNA polymerase I. Precipitation of nicked DNA with cold KCl in the presence of sodium dodecyl sulfate suggests the existence of protein covalently attached to the nicked DNA molecule. The covalent nature of this interaction has been directly demonstrated by transfer of radiolabeled phosphate from DNA to protein. On the basis of these results, we propose that helicase I becomes covalently bound to the 5' end of the nicked DNA strand as part of the reaction mechanism for phosphodiester bond cleavage. A model is presented to suggest how helicase I could nick the F plasmid at oriT and subsequently unwind the duplex DNA to provide single-stranded DNA for strand transfer during bacterial conjugation.
Search for dark matter with IACTs and the Cherenkov Telescope Array
Creators: name: Morselli, Aldo
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the last decades an incredible amount of evidence for the existence of dark matter (DM) has been accumulating. At the same time, many efforts have been undertaken to try to identify what dark matter is made of. Indirect searches look at places in the Universe where dark matter is known to be abundant and seek for possible annihilation or decay signatures. Indirect searches with the Fermi Gamma ray Space Telescope and Imaging Atmospheric Cherenkov Telescopes (IACTs) are playing a crucial role in constraining the nature of the DM particle through the study of their annihilation into gamma rays from different astrophysical structures. In this talk I will review the status of the search with IACTs and I will describe the sensitivity projections for dark matter searches on the various targets taking into account the latest instrument response functions expected for the Cherenkov Telescope Array (CTA) together with estimations for the systematic uncertainties from diffuse astrophysical and cosmic-ray
description: 6 pages, 7 figures, 12th Cosmic Ray International Seminar - CRIS 2022
Cloning and characterization of the Pseudomonas aeruginosa sodA and sodB genes encoding manganese- and iron-cofactored superoxide dismutase: demonstration of increased manganese superoxide dismutase activity in alginate-producing bacteria.
Creators: name: Vasil, M L
name: Wozniak, D J
name: Woodruff, W A
name: Ohman, D E
name: Hassett, D J
name: Cohen, M S
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Pseudomonas aeruginosa is a strict aerobe which is likely exposed to oxygen reduction products including superoxide and hydrogen peroxide during the metabolism of molecular oxygen. To counterbalance the potentially hazardous effects of elevated endogenous levels of superoxide, most aerobic organisms possess one or more superoxide dismutases or compounds capable of scavenging superoxide. We have previously shown that P. aeruginosa possesses both an iron- and a manganese-cofactored superoxide dismutase (D. J. Hassett, L. Charniga, K. A. Bean, D. E. Ohman, and M. S. Cohen, Infect. Immun. 60:328-336, 1992). In this study, the genes encoding manganese (sodA)- and iron (sodB)- cofactored superoxide dismutase were cloned by using a cosmid library of P. aeruginosa FRD which complemented an Escherichia coli (JI132) strain devoid of superoxide dismutase activity. The sodA and sodB genes of P. aeruginosa, when cloned into a high-copy-number vector (pKS-), partially restored the aerobic growth rate defect, characteristic of the Sod- strain, to that of the wild type (AB1157) when grown in Luria broth. The nucleotide sequences of sodA and sodB have open reading frames of 612 and 579 bp that encode dimeric proteins of 22.9 and 21.2 kDa, respectively. These data were also supported by the results of in vitro expression studies. The deduced amino acid sequence of the P. aeruginosa manganese and iron superoxide dismutase revealed approximately 50 and 67% similarity with manganese and iron superoxide dismutases from E. coli, respectively. There was also remarkable similarity with iron and manganese superoxide dismutases from other phyla. The mRNA start site of sodB was mapped to 174 bp upstream of the ATG codon. A likely promoter with similarity to the -10 and -35 consensus sequence of E. coli was observed upstream of the ATG start codon of sodB. Regions sequenced 519 bp upstream of the sodA electrophoresis, sodA gene revealed no such promoter, suggesting an alternative mode of control for sodA. By transverse field electrophoresis, sodA and sodB were mapped to the 71- to 75-min region on the P. aeruginosa PAO1 chromosome. Strikingly, mucoid alginate-producing bacteria generated greater levels of manganese superoxide dismutase than nonmucoid revertants, suggesting that mucoid P. aeruginosa is responding to oxidative stress and/or changes in the redox status of the cell.
Realization of Heisenberg models of spin systems with polar molecules in pendular states
Creators: name: Yue, Wenjing
name: Wei, Qi
name: Kais, Sabre
name: Friedrich, Bretislav
name: Herschbach, Dudley
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We show that ultracold polar diatomic or linear molecules, oriented in an external electric field and mutually coupled by dipole-dipole interactions, can be used to realize the exact Heisenberg XYZ, XXZ and XY models without invoking any approximation. The two lowest lying excited pendular states coupled by microwave or radio-frequency fields are used to encode the pseudo-spin. We map out the general features of the models by evaluating the models' constants as functions of the molecular dipole moment, rotational constant, strength and direction of the external field as well as the distance between molecules. We calculate the phase diagram for a linear chain of polar molecules based on the Heisenberg models and discuss their drawbacks, advantages, and potential applications.
description: 23 pages, 8 figures
Double helicase II (uvrD)-helicase IV (helD) deletion mutants are defective in the recombination pathways of Escherichia coli.
Creators: name: Matson, S W
name: Mendonca, V M
name: Kaiser-Rogers, K
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: The Escherichia coli helD (encoding helicase IV) and uvrD (encoding helicase II) genes have been deleted, independently and in combination, from the chromosome and replaced with genes encoding antibiotic resistance. Each deletion was verified by Southern blots, and the location of each deletion was confirmed by P1-mediated transduction. Cell strains containing the single and double deletions were viable, indicating that helicases II and IV are not essential for viability. Cell strains lacking helicase IV (delta helD) exhibited no increase in sensitivity to UV irradiation but were slightly more resistant to methyl methanesulfonate (MMS) than the isogenic wild-type cell strain. As expected, cell strains containing the helicase II deletion (delta uvrD) were sensitive to both UV irradiation and MMS. The introduction of the helicase IV deletion into a delta uvrD background had essentially no effect on the UV and MMS sensitivity of the cell strains analyzed. The double deletions, however, conferred a Rec- mutant phenotype for conjugational and transductional recombination in both recBC sbcB(C) and recBC sbcA backgrounds. The Rec- mutant phenotype was more profound in the recBC sbcB(C) background than in the recBC sbcA background. The recombination-deficient phenotype indicates the direct involvement of helicase II and/or helicase IV in the RecF pathway [recBC sbcB(C) background] and RecE pathway (recBC sbcA background) of recombination. The modest decrease in the recombination frequency observed in single-deletion mutants in the recBC sbcB(C) background suggests that either helicase is sufficient. In addition, helicase IV has been overexpressed in a tightly regulated system. The data suggest that even modest overexpression of helicase IV is lethal to the cell.
Expression of gonococcal transferrin-binding protein 1 causes Escherichia coli to bind human transferrin.
Creators: name: Cornelissen, C N
name: Biswas, G D
name: Sparling, P F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: The gene for gonococcal transferrin-binding protein 1 (TBP1) was cloned behind an inducible promoter in Escherichia coli. The resultant strain was capable of binding human transferrin with the same specificity as that of the gonococcus. E. coli expressing TBP1 did not internalize transferrin-bound iron or grow on transferrin as a sole iron source.
A geometric view on local Lorentz transformations in teleparallel gravity
Creators: name: Hohmann, Manuel
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Local Lorentz transformations play an important role in teleparallel gravity theories, in which a tetrad is conventionally employed as a fundamental field variable describing the gravitational field. It is commonly understood that modifications of general relativity in the teleparallel framework break a certain notion of local Lorentz invariance, which is present in the pure tetrad formulation of such theories, while another notion present in the covariant formulation is preserved. We illuminate these different notions from a geometric perspective, and distinguish them from what is commonly understood as breaking of local Lorentz invariance in the context of gravity phenomenology. Based on physical arguments, we present a geometric interpretation of the dynamical fields in teleparallel gravity, which unified and refines the conventional approaches.
description: 19 pages, no figures; contribution to the Special Issue of the International Journal of Geometric Methods in Modern Physics dedicated to the conference Geometric Foundations of Gravity in Tartu 2021
Neisseria meningitidis produces iron-regulated proteins related to the RTX family of exoproteins.
Creators: name: West, A
name: Thompson, S A
name: Wang, L L
name: Sparling, P F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: A monoclonal antibody (A4.85) which reacted with Fe-regulated proteins of Neisseria meningitidis, was used to isolate a lambda gt11 clone from N. meningitidis FAM20. Chromosomal fragments flanking the fragment expressing the A4.85 epitope were cloned, and their DNA sequences revealed a 3,345-bp open reading frame predicting a 122-kDa protein. This gene was named frpA (Fe-regulated protein). A computer similarity search of GenBank revealed high levels of similarity to members of the RTX family of cytotoxins, especially in a region of tandem 9-amino-acid repeats. These repeats are found in all members of the RTX family; similar repeats were present 13 times in the predicted FrpA protein. Antigenic relatedness between the meningococcal proteins and the RTX proteins was demonstrated by the reactivity of A4.85 with Escherichia coli hemolysin (HlyA) and Bordetella pertussis adenylate cyclase-hemolysin (CyaA). Similarly, FrpA was recognized by 9D4, a monoclonal antibody directed against B. pertussis CyaA. In addition to the frpA gene, a second gene (frpC) produced a larger RTX-related protein. The frpA and frpC loci were mutagenized in strain FAM20, resulting in the loss of RTX-related proteins. A 120-kDa protein was expressed from the reconstructed frpA gene in E. coli. The biological function of FrpA is unknown, but its similarity to other RTX toxins suggests that it may play an important role in the pathogenesis of meningococcal infection.
Китайские инвестиции в России: отраслевой срез
Creators: name: Александрова Мария Викторовна
Publisher: name: Китай в мировой и региональной политике. История и современность
Year: 2017
Subjects: ЭЛЕКТРОЭНЕРГЕТИКА
ТЭЦ
МЕЖПРАВИТЕЛЬСТВЕННАЯ КОМИССИЯ
ГЭС
ВЕТРОЭЛЕКТРОСТАНЦИЯ
ГЕЛИОЭНЕРГЕТИКА
ТРАНСПОРТНАЯ ИНФРАСТРУКТУРА
СЕВЕРНЫЙ МОРСКОЙ ПУТЬ
"БЕЛКОМУР"
МОРСКОЙ ПОРТ
АВТОМОБИЛЕСТРОЕНИЕ
GREAT WALL
LIFAN
ОТВЕРТОЧНАЯ СБОРКА
КРУПНОУЗЛОВАЯ СБОРКА
ЛОКАЛИЗАЦИЯ ПРОИЗВОДСТВА
ОБЪЕМ ИНВЕСТИЦИЙ
АВТОМОБИЛЬНОЕ СТЕКЛО
ЗАКОНОДАТЕЛЬСТВО

description: В последние годы китайские инвесторы в РФ открыли для себя новые сферы приложения капитала. На примере электроэнергетического комплекса автор рассматривает китайский опыт вложения капитала, при этом отмечается, что китайцы совершенно не готовы к серьезным проектам, прежде всего с технической точки зрения. А на примере автомобилестроения проанализированы несколько китайских проектов создания собственного промышленного производства в России, которые преследует череда неудач, из чего автор делает вывод, что перед принятием важных инвестиционных решений предприниматели из КНР не проводят серьезных маркетинговых исследований. Отдельно поднимается вопрос найма российских граждан на китайские предприятия, где отсутствует понятие о технике безопасности, охране труда, уважении российского трудового законодательства и др.
Stochastic switching in delay-coupled oscillators
Creators: name: D'Huys, Otti
name: Juengling, Thomas
name: Kinzel, Wolfgang
Publisher: name: arXiv
Year: 2014
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: A delay is known to induce multistability in periodic systems. Under influence of noise, coupled oscillators can switch between coexistent orbits with different frequencies and different oscillation patterns. For coupled phase oscillators we reduce the delay system to a non-delayed Langevin equation, which allows us to analytically compute the distribution of frequencies, and their corresponding residence times. The number of stable periodic orbits scales with the roundtrip delay time and coupling strength, but the noisy system visits only a fraction of the orbits, which scales with the square root of the delay time and is independent of the coupling strength. In contrast, the residence time in the different orbits is mainly determined by the coupling strength and the number of oscillators, and only weakly dependent on the coupling delay. Finally we investigate the effect of a detuning between the oscillators. We demonstrate the generality of our results with delay-coupled FitzHugh-Nagumo oscillators.
Regions of maltose-binding protein that influence SecB-dependent and SecA-dependent export in Escherichia coli.
Creators: name: Bassford, P J
name: Strobel, S M
name: Cannon, J G
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: In Escherichia coli, the efficient export of maltose-binding protein (MBP) is dependent on the chaperone SecB, whereas export of ribose-binding protein (RBP) is SecB independent. To localize the regions of MBP involved in interaction with SecB, hybrids between MBP and RBP in SecB mutant cells were constructed and analyzed. One hybrid consisted of the signal peptide and first third of the mature moiety of MBP, followed by the C-terminal two-thirds of RBP (MBP-RBP112). This hybrid was dependent upon SecB for its efficient export and exhibited a strong export defect in secA mutant cells. A hybrid between RBP and MBP with the same fusion point was also constructed (RBP-MBP116). The RBP-MBP116 hybrid remained SecB independent and only exhibited a partial export defect in secA mutant cells. In addition, MBP species with specific alterations in the early mature region were less dependent on SecB for their efficient export. The export of these altered MBP species was also less affected in secA mutant cells and in cells treated with sodium azide. These results present additional evidence for the targeting role of SecB.
К вопросу о подключении проекта развития Северного морского пути к китайскому стратегическому плану «Один пояс, один путь» (взаимодополняемость, препятствия и возможные направления)
Creators: name: Сюй Гуанмяо
Publisher: name: Китай в мировой и региональной политике. История и современность
Year: 2017
Subjects: АРКТИКА
СЕВЕРНЫЙ МОРСКОЙ ПУТЬ (СМП)
КИТАЙ
«ОДИН ПОЯС
ОДИН ПУТЬ»
РОССИЙСКО-КИТАЙСКОЕ СОТРУДНИЧЕСТВО

description: В статье рассматриваются вопросы взаимодополняемости проекта развития Северного морского пути и китайского стратегического проекта/плана «Один пояс, один путь», а также препятствия и возможные направления/формы включения проекта развития СМП в китайскую инициативу. Автор приходит к выводу, что условия для официального включения еще не созрели. Однако начать обсуждение его перспектив и возможных форм вполне реально. Одним из возможных путей здесь может стать участие отдельных предприятий и региональных правительств в проекте развития и использования СМП. В случае достижения первых положительных результатов следует перейти к следующему этапу заключению договоров на уровне правительств двух стран. Заключительный этап реализация запланированных проектов.
Modeling COVID-19 Transmission using IDSIM, an Epidemiological-Modelling Desktop App with Multi-Level Immunization Capabilities
Creators: name: Nichita, Eleodor
name: Pietrusiak, Mary-Anne
name: Xie, Fangli
name: Schwanke, Peter
name: Pandya, Anjali
Publisher: name: arXiv
Year: 2021
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: The COVID-19 pandemic has placed unprecedented demands on local public health units in Ontario, Canada, one of which was the need for in-house epidemiological-modelling capabilities. To address this need, Ontario Tech University and the Durham Region Health Department developed a native Windows desktop app that performs epidemiological modelling of infectious diseases. The app is an implementation of a multi-stratified compartmental epidemiological model that can accommodate multiple virus variants and levels of vaccination, as well as public health measures such as physical distancing, contact tracing followed by quarantine, and testing followed by isolation. This article presents the epidemiological model and epidemiological-simulation results obtained using the developed app. The simulations investigate the effects of different factors on COVID-19 transmission in Durham Region, including vaccination coverage, vaccine effectiveness, waning of vaccine-induced immunity, advent of the Omicron variant and effect of COVID-19 booster vaccines in reducing the number of infections and severe cases. Results indicate that, for the Delta variant, natural immunity, in addition to vaccination-induced immunity, is necessary to achieve herd immunity and that waning of vaccine-induced immunity lengthens the time necessary to reach herd immunity. In the absence of additional public health measures, a wave driven by the Omicron variant is predicted to pose significant public health challenges with infections predicted to peak in approximately two to three months, depending on the rate of administration of booster doses.
description: 28 pages, 8 figures
Completed STROBE guidelines checklist for observational studies of the manuscript "Sex-related differences in symptom presentation of patients with aneurysmal subarachnoid hemorrhage"
Creators: name: Westphal, Laura P.
name: Bögli, Stefan Y.
name: Werner, J.
name: Casagrande, F.
name: Keller, E.
name: Brandi, G.
Publisher: name: Zenodo
Year: 2022

description: Completed STROBE guidelines checklist for observational studies.
An unusual gene containing a dnaJ N-terminal box flanks the putative origin of replication of Mycoplasma genitalium.
Creators: name: Bott, K F
name: Bailey, C C
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Origins of replication are known to be highly conserved among widely divergent microbial species, with the gene order in those regions being dnaA-dnaN-recF-gyrB. On the basis of sequence identities to entries in GenBank, the gene order of a 6-kb fragment of Mycoplasma genitalium DNA was determined to be dnaN-orf311-gyrB-gyrA-serS, which is structurally similar to the ancestral origin of replication. We have directly linked the dnaN gene to the M. genitalium dnaA gene by PCR amplification. However, we found a novel open reading frame, designated orf311, in place of an expected sequence encoding recF. Orf311 contains a DnaJ box motif at its N terminus, but it has no overall homology to any other protein or sequence in the database. We are unable to detect any recF homolog in M. genitalium by hybridization or during a random sequencing survey of the genome.
An unstructured CD-grid variational formulation for sea ice dynamics
Creators: name: Capodaglio, Giacomo
name: Petersen, Mark R.
name: Turner, Adrian K.
name: Roberts, Andrew F.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: For the numerical simulation of earth system models, Arakawa grids are largely employed. A quadrilateral mesh is assumed for their classical definition, and different types of grids are identified depending on the location of the discretized quantities. The B-grid has both velocity components at the center of a cell, the C-grid places the velocity components on the edges in a staggered fashion, and the D-grid is a ninety-degree rotation of a C-grid. Historically, B-grid formulations of sea ice dynamics have been dominant because they have matched the grid type used by ocean models. In recent years, as ocean models have increasingly progressed to C-grids, sea ice models have followed suit on quadrilateral meshes, but few if any implementations of unstructured C-grid sea ice models have been developed. In this work, we present an unstructured CD-grid type formulation of the elastic-viscous-plastic rheology, where the velocity unknowns are located at the edges, rather than at the vertices, as in the B-grid. The notion of a CD-grid has been recently introduced and assumes that the velocity components are co-located at the edges. The mesh cells in our analysis have $n$ sides, with $n$ greater than or equal to four. Numerical results are included to investigate the features of the proposed method. Our framework of choice is the Model for Prediction Across Scales (MPAS) within E3SM, the climate model of the U.S. Department of Energy, although our approach is general and could be applied to other models as well. While MPAS-Seaice is currently defined on a B-grid, MPAS-Ocean runs on a C-grid, hence interpolation operators are heavily used when coupled simulations are performed. The discretization introduced here aims at transitioning the dynamics of MPAS-Seaice to a CD-grid, to ultimately facilitate improved coupling with MPAS-Ocean and reduce numerical errors associated with this communication.
«Экономический пояс Шелкового пути» как механизм экономической геополитики Китая в постсоветских странах
Creators: name: Мокрецкий Александр Чеславович
Publisher: name: Китай в мировой и региональной политике. История и современность
Year: 2017
Subjects: КИТАЙ
БЕЛАРУСЬ
МОЛДОВА
УКРАИНА
АЗЕРБАЙДЖАН
АРМЕНИЯ
ГРУЗИЯ
ЭКОНОМИЧЕСКИЙ ПОЯС ШЕЛКОВОГО ПУТИ

description: 2017 год юбилейный год для стран Содружества Независимых Государств и их отношений с Китайской Народной Республикой. Ровно четверть века назад одна за другой постсоветские страны установили дипломатические отношения с Китаем, и в течение 25 лет их двустороннее сотрудничество с КНР поступательно развивается. Пекин, весьма заинтересованный в поиске новых возможностей для реализации собственных задач, комплексно «осваивает» территорию СНГ, увязывает свое развитие с развитием каждой из постсоветских стран. В рамках данной статьи автор рассматривает шесть постсоветских государств (Беларусь, Молдова и Украина и Закавказье Азербайджан, Армения и Грузия) в плане оценки влияния китайского фактора на их развитие в ходе реализации инициативы «Один пояс, Один путь».
Inefficiency of voting in Parrondo games
Creators: name: Dinis, L.
name: Parrondo, J. M. R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computer Science and Game Theory (cs.GT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We study a modification of the so-called Parrondo's paradox where a large number of individuals choose the game they want to play by voting. We show that it can be better for the players to vote randomly than to vote according to their own benefit in one turn. The former yields a winning tendency while the latter results in steady losses. An explanation of this behaviour is given by noting that selfish voting prevents the switching between games that is essential for the total capital to grow. Results for both finite and infinite number of players are presented. It is shown that the extension of the model to the history-dependent Parrondo's paradox also displays the same effect.
description: 11 pages, 6 figures
Interactions between a central bubble and a surrounding bubble cluster
Creators: name: Zhang, A-Man
name: Li, Shi-Min
name: Cui, Pu
name: Li, Shuai
name: Liu, Yun-Long
Publisher: name: arXiv
Year: 2023
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The interaction of multiple bubbles is a complex physical problem. A simplified case of multiple bubbles is studied theoretically with a bubble located at the center of a circular bubble cluster. All bubbles in the cluster are equally spaced and own the same initial conditions as the central bubble. The unified theory for bubble dynamics (Zhang et al. arXiv:2301.13698) is applied to model the interaction between the central bubble and the circular bubble cluster. To account for the effect of the propagation time of pressure waves, the emission source of the wave is obtained by interpolating the physical information on the time axis. An underwater explosion experiment with two bubbles of different scales is used to validate the theoretical model. The effect of the bubble cluster with a variation in scale on the pulsation characteristics of the central bubble is studied.
Locations of genetic markers on the physical map of the chromosome of Neisseria gonorrhoeae FA1090.
Creators: name: Cannon, J G
name: Dempsey, J A
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: To increase the utility of the previously constructed physical map of the chromosome of Neisseria gonorrhoeae FA1090, 28 additional genetic markers were localized on the map. Cloned gonococcal genes were used to probe Southern blots of restriction enzyme-digested DNA separated on pulsed-field gels, thus identifying the fragment in each of several digests to which the probe hybridized and the map location of each gene. The addition of the new markers brings the total number of mapped loci for this strain to 68; the locations of all of those markers on the updated map are shown.
The landscape of massive black-hole spectroscopy with LISA and Einstein Telescope
Creators: name: Bhagwat, Swetha
name: Pacilio, Costantino
name: Barausse, Enrico
name: Pani, Paolo
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Measuring the quasi-normal mode~(QNM) spectrum emitted by a perturbed black-hole~(BH) --~also known as BH spectroscopy~-- provides an excellent opportunity to test the predictions of general relativity in the strong-gravity regime. We investigate the prospects and precision of BH spectroscopy in massive binary black hole ringdowns, one of the primary science objectives of the future Laser Interferometric Space Antenna~(LISA) mission. We simulate various massive binary BH population models, featuring competing prescriptions for the Delays between galaxy and BH mergers, for the impact of supernova feedback on massive BH growth, and for the initial population of high redshift BH seeds (light versus heavy seeds). For each of these scenarios, we compute the average number of expected events for precision BH spectroscopy using a Fisher-matrix analysis. We find that, for any heavy seed scenario, LISA will measure the dominant mode frequency within ${\cal O}(0.1) \%$ relative uncertainty and will estimate at least 3 independent QNM parameters within $1 \%$ error. The most optimistic heavy seed scenarios produce $\mathcal{O}(100)$ events with $1 \%$ measurability for 3 or more QNM quantities during LISA's operational time. On the other hand, light seed scenarios produce lighter merger remnants, which ring at frequencies higher than LISA's sensitivity. Interestingly, the light seed models give rise to a fraction of mergers in the band of Einstein Telescope, allowing for the measurement of 3 QNM parameters with $\sim 10 \%$ relative errors in approximately a few to ten events/yr. More precise BH spectroscopy in the light seed scenarios would require instruments operating in the deciHertz band.
description: 19 pages, 10 figures
Computation of many-particle quantum trajectories with exchange interaction: Application to the simulation of nanoelectronic devices
Creators: name: Alarcón, A.
name: Yaro, S.
name: Cartoixà, X.
name: Oriols, X.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 81V70

description: Following Ref. [Oriols X 2007 Phys. Rev. Lett., 98 066803], an algorithm to deal with the exchange interaction in non-separable quantum systems is presented. The algorithm can be applied to fermions or bosons and, by construction, it exactly ensures that any observable is totally independent from the interchange of particles. It is based on the use of conditional Bohmian wave functions which are solutions of single-particle pseudo-Schrödinger equations. The exchange symmetry is directly defined by demanding symmetry properties of the quantum trajectories in the configuration space with a universal algorithm, rather than through a particular exchange-correlation functional introduced into the single-particle pseudo-Schrödinger equation. It requires the computation of N^2 conditional wave functions to deal with N identical particles. For separable Hamiltonians, the algorithm reduces to the standard Slater determinant for fermions, or permanent for bosons. A numerical test for a two-particle system, where exact solutions for non-separable Hamiltonians are computationally accessible, is presented. The numerical viability of the algorithm for quantum electron transport (in a far-from equilibrium time-dependent open system) is demonstrated by computing the current and fluctuations in a nano-resistor, with exchange and Coulomb interactions among electrons.
description: 31 pages, 15 figures