cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Kolmogorov's dissipation number and the number of degrees of freedom for the 3D Navier-Stokes equations
Creators: name: Cheskidov, Alexey
name: Dai, Mimi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 35Q35, 37L30

description: Kolmogorov's theory of turbulence predicts that only wavenumbers below some critical value, called Kolmogorov's dissipation number, are essential to describe the evolution of a three-dimensional fluid flow. A determining wavenumber, first introduced by Foias and Prodi for the 2D Navier-Stokes equations, is a mathematical analog of Kolmogorov's number. The purpose of this paper is to prove the existence of a time-dependent determining wavenumber for the 3D Navier-Stokes equations whose time average is bounded by Kolmogorov's dissipation wavenumber for all solutions on the global attractor whose intermittency is not extreme.
description: Revised version
Assessment of the Timing of the Virgilina Deformation with U-Pb Ages of Plutonic and Volcanic Rocks in the Carolina Terrane
Creators: name: Goliber, Skylar Fay Beadle
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: The undeformed Farrington pluton in the Carolina Terrane of North Carolina was thought to be contemporaneous with nearby volcanic rocks, mapped as the deformed Virgilina Sequence. This relationship was also hypothesized to be diagnostic of the timing and duration of the Virgilina deformation event. New U-Pb zircon ages for the Farrington pluton and the volcanic Member presumed to be from the Virgilina sequence demonstrate that the correlation is incorrect. Nine concordant zircons from the East Farrington pluton yielded a weighted mean age of 569.0 ± 1.1 Ma. Three concordant zircons from rocks mapped as the Virgilina Sequence yield a weighted mean age of 548.7 ± 1.1 Ma. These data suggest that the Farrington pluton is younger than previously assumed (~569 Ma vs. ~579 Ma). Moreover, the new date for volcanic rocks interpreted to be in the Virgilina Sequence suggests that the rocks belong to the much younger (~550 Ma) Uwharrie Formation, the volcanic portion of the more recent Albemarle Arc. These outcrops extend exposure of the arc much farther northeast than previously recognized. The new geochronologic data suggest that the Virgilina deformation likely occurred between the deposition of the Aaron Formation (~588 Ma) and the intrusion of the Farrington pluton (~569 Ma).
PocketCoffea: a configuration layer for CMS analyses with Coffea
Creators: name: Marchegiani, Matteo
Publisher: name: Zenodo
Year: 2023

description: A configuration layer for the analysis of CMS data in the NanoAOD format is presented. The framework is based on the columnar analysis of proton-proton collision events with the Coffea Python package and it focuses on configurability and reproducibility of analysis tasks. All the operations needed to extract the relevant information from events are performed by a Coffea processor object that takes the NanoAOD events as input and returns a set of output histograms or arrays.
 PocketCoffea defines a configuration scheme to specify all the parameters and settings of the processor: the datasets definition, object and event selections, Monte Carlo weights, systematic uncertainties and the output histograms characteristics. The configuration layer is user friendly and speeds up the setup of many common analysis tasks.
 A structured processor performing operations that are common among CMS analyses is defined and can be customized with derived processor classes, allowing code sharing between different analyses workflows in a hierarchical structure.
 With its configurable structure, PocketCoffea is a suitable tool to perform any CMS analysis in a highly reproducible, computational efficient and user-friendly way.
HEK293 cell and 293 sublineage cells (Epstein-Barr virus (EBV) latent infection) Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2017
Subjects: genome sequencing
Multiisolate

description: Epstein-Barr virus (EBV) latent infection facilitated the tumorigenicity was previously established using the Maxi-EBV system. The LMP1 gene in Maxi-EBV genome was replaced by that of nasopharyngeal carcinoma origin. By using the Maxi-EBV system and immortalized 293 epithelial cell line with low malignancy, we previously developed the cell line 293-EBV, and established a tumor model in nude mice.The cell line 293–1/NL with the replacement of N-LMP1(21 strains of full-lenthLMP1 genes of NPC origin) in EBV genome showed much lower tumorigenicity than the original 293-EBV cell lineThe resultant cell line, 293–1/NL showed much lowermalignancy than the original 293-EBV. The result was opposite to our expectation. The change of 293 sublineage cells for EBV harboring also got similar result. To seek the underlying reason, the copy number of EBV genome in all the cell lines was detected. The result indicated that 293-EBV contained about 4.5-fold higher EBV copies than 293–1/NL did. Parallel EBV genomes led to relatively stable copies in different 293 sublineages, suggesting the viral genome structure is a factor for the sustainability of EBV’s copy number. The sub-lineage 293–2 has a higher ability to form tumors in nude mice than 293–1. In order to verify above result for N-LMP1 in genome analysis, these two EBV genomes containing B-LMP1 (wildtype B95–8 strain) or N-LMP1 were introduced into 293–2 cells respectively. Two cell lines, C2089 and C22, were accordingly produced after hygromycin selection process . As shown in the tumor formation test , from the tumor growth sizes within 5 weeks,C22 also showed lower malignancy than C2089.
The Search For Photon-Induced Metal Hydride Formation and Modeling of Multi-Step Multi-Electron Electrocatalytic Reactions at the Rotating Disc Electrode
Creators: name: Gruninger, Cole
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: This thesis contains three separate chapters regarding three different research projects. The first two projects encompass the study of transition metal hydrides: synthesizing them and generating them from visible light. The third chapter focuses on the modeling of multi-electron multi-step electrocatalytic reactions at the rotating disk electrode. Potential applications concerning this work are within the area of energy storage.
THE ROLE OF THEODORE DREISER IN AMERICAN LITERATURE
Creators: name: Khayrullayeva, Yulduz
Publisher: name: Zenodo
Year: 2024

description: Theodore Dreiser was a significant figure in American literature, particularly known for his role in the naturalist movement. Born in 1871, Dreiser's work is marked by its realistic depiction of the struggles of individuals against societal and economic forces. Dreiser was a prominent naturalist writer, a movement that sought to portray life with scientific objectivity, focusing on the influence of environment and heredity on human behavior. His works often emphasize the darker, more deterministic aspects of human existence.
Recombination era magnetic fields from axion dark matter
Creators: name: Banik, Nilanjan
name: Christopherson, Adam J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We introduce a new mechanism for generating magnetic fields in the recombination era. This Harrison-like mechanism utilizes vorticity in baryons that is sourced through the Bose-Einstein condensate of axions via gravitational interactions. The magnetic fields generated are on the galactic scales $\sim 10\,{\rm kpc}$ and have a magnitude of the order of $B\sim10^{-23}\,{\rm G}$ today. The field has a greater magnitude than those generated from other mechanisms relying on second order perturbation theory, and is sufficient to provide a seed for battery mechanisms.
description: 4 pages; v2: minor changes, references added
Theoretical energy level spectra and transition data for 4p$^6$4d$^2$, 4p$^6$4d4f and 4p$^5$4d$^3$ configurations of W$^{36+}$ ion
Creators: name: Bogdanovich, P.
name: Kisielius, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The ab initio quasirelativistic Hartree-Fock method developed specifically for the calculation of spectral parameters of heavy atoms and highly charged ions is used to derive transition data for multicharged tungsten ion. The configuration interaction method is applied to include electron correlation effects. The relativistic effects are taken into account in the Breit-Pauli approximation for quasirelativistic Hartree-Fock radial orbitals. The energy level spectra, radiative lifetimes $τ$, Lande $g$-factors are calculated for the $\mathrm{4p^64d^2}$, $\mathrm{4p^64d4f}$ and $\mathrm{4p^54d^3}$ configurations of W$^{36+}$ ion. The transition wavelengths $λ$, spontaneous transition probabilities $A$, oscillator strengths $gf$ and line strengths $S$ for the electric dipole, electric quadrupole, electric octupole and magnetic dipole transitions among the levels of these configurations are tabulated.
Examining Mothers' and Fathers' Contributions to Ethnic-Racial Identity Development
Creators: name: Maya, Anabelle
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Studies have suggested that parental ethnic-racial identity is associated, indirectly and directly, with adolescents own ethnic-racial identity (ERI) and developmental outcomes. Although studies have shown that mothers’ and fathers’ ethnic-racial identity are individually related to adolescent adjustment, few studies have examined their collective influence. In particular, very little attention has been given to mother-father similarity or difference in ERI as well as potential implications for adolescents. The current study addressed three specific questions: (1) How similar or different are mothers’ and fathers’ ERI? (2) How does mother-father ERI and similarity/difference relate to adolescent ERI and adjustment (e.g., depressive symptoms; self-esteem; school engagement; grades)? (3) How does adolescent ERI influence adjustment? The study sample was comprised of 99 African American mother-father dyads with adolescents. Paired t-tests and absolute difference scores were computed to examine parental similarity and difference in ERI (racial centrality; public and private regard). Pearson correlations were conducted to explore: 1) how mothers’ and fathers’ ERI is related to adolescents’ ERI and adjustment and 2) how parental similarity/difference was related to adolescent ERI and adolescent adjustment. Results indicated that fathers had significantly higher racial centrality than mothers. Absolute difference scores revealed that: 1) fathers and mothers were relatively similarly in private regard and 2) although fathers reported higher public regard and racial centrality, there relatively little discrepancy between parents. Additionally, results indicated that, while mothers’ centrality was associated with fewer depressive symptoms, fathers’ racial centrality was associated with greater public regard among adolescents. Although marginally significant, analyses revealed that a greater discrepancy in parents’ public regard was associated with less school effort among adolescents (r = -.181; p< .10). Results also indicated that adolescents’ who held more positive views about their racial group reported greater school effort, self-esteem, & higher grades. Overall, study findings suggest that mothers’ and fathers’ ERI, individually and collectively, has implications for adolescents’ own ERI and adjustment. Additionally, this investigation suggested that adolescents’ views about their racial group are related to adolescent adjustment.
Mangrovicella endophytica strain:5T4P-12-1 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2018
Subjects: Genome sequencing and assembly
Monoisolate

description: Mangrovicella endophytica gen. nov., sp. nov., a new member of the family Aurantimonadaceae isolated from Aegiceras corniculatum
Presented in Partial Fulfillment of the Requirements for the Degree of Masters of Science in Economics (International Economics)
Creators: name: Amanuel Tesfaye
Publisher: name: Zenodo
Year: 2019

description: This paper attempts to study the determinant of FDI in Ethiopia for the time period from 1980-2015. To this end, the study has reviewed theoretical explanations relating to the determinants of foreign direct investment and the study has also reviewed relevant empirical literatures focusing on the determinants of FDI in the context of developing countries. Using Data on foreign direct investment and number of telephone users that is obtained from United Nations Conference on Trade and Development (UNCTAD). Real effective exchange rate, inflation rate, export and import data were obtained from National Bank of Ethiopia (NBE), and Ethiopia Real GDP from Ministry of Finance and Economic Development (MoFED). By adopting model that was used by Erdal Demirhan etal (2008) this paper examine prominent determinants of FDI and finds that economic growth, macroeconomic stability, openness to trade are important determinants of foreign direct investment. The results suggest policy makers should give due attention to promoting liberalization and implementing sound economic policies that can ensure macroeconomic stability in the country.

Key words:
As far as the frog can see: Visual acuity in two tropical frog species
Creators: name: Giffin, Kate
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Visual acuity, the clarity of vision, is an important aspect of the visual system. Understanding the visual acuity of various species provides insight into how animals perceive and interact with their environment, and it helps to create a cohesive story of how vision and visual behaviors evolved. However, little is known about the visual acuities of anurans. Thus, we used the optomotor response to behaviorally quantify the acuity of two small, tropical frog species: the green-and-black poison dart frog, Dendrobates auratus, and the tùngara frog, Engystomops pustulosus. These frogs differ slightly in their natural histories, leading us to hypothesize that the poison frogs had higher visual acuities than the tùngara. To determine their visual acuity, we exposed the frogs to rotating black and white stripes of decreasing widths. They would exhibit the optomotor response by reflexively turning when viewing the stripes. We then calculated visual acuity as minimum separable angle (MSA) by determining the threshold of discrimination, or the narrowest stripe widths the frogs could perceive, based on whether they exhibited a positive optomotor response to that stripe width. We calculated the MSA of poison frogs as 4.033° and the MSA of tùngara frogs as 4.839°. These MSAs are weaker than previous visual acuities reported in two other larger species of frogs. This finding is consistent with visual acuity trends, as there is a positive relationship between body size and acuity. Our findings about the perceptual abilities of these small, tropical frogs warrants future research into visually dependent behaviors such as hunting and communication. Furthermore, this study contributes to the field of visual ecology by providing visual acuities for more anuran species, another piece in the puzzle of the evolution of the visual system and the behaviors that rely upon it.
Computation of 2D Fourier transforms and diffraction integrals using Gaussian radial basis functions
Creators: name: Martinez-Finkelshtein, A.
name: Ramos-Lopez, D.
name: Iskander, D. R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We implement an efficient method of computation of two dimensional Fourier-type integrals based on approximation of the integrand by Gaussian radial basis functions, which constitute a standard tool in approximation theory. As a result, we obtain a rapidly converging series expansion for the integrals, allowing for their accurate calculation. We apply this idea to the evaluation of diffraction integrals, used for the computation of the through-focus characteristics of an optical system. We implement this method and compare it performance in terms of complexity, accuracy and execution time with several alternative approaches, especially with the extended Nijboer-Zernike theory, which is also outlined in the text for the reader's convenience. The proposed method yields a reliable and fast scheme for simultaneous evaluation of such kind of integrals for several values of the defocus parameter, as required in the characterization of the through-focus optics.
description: 46 pages, 5 figures. An updated on the ENZ computation is included
Modeling, Simulating and Quantification of Optical Images of Ultrasound Contrast Bubbles
Creators: name: Habtamu Abraham
Publisher: name: Zenodo
Year: 2024

description: Microbubble based ultrasound contrast agents are being used in clinical settings to enhance backscattered ultrasound signal from blood pool during perfusion and blood flow measurements. Often individual bubbles are characterized optically by recording their vibrations with a fast framing camera and direct quantitative information on their dynamic behavior can be derived. Nonetheless, when a three-dimensional object, stack of infinitely thin two-dimensional layers, is imaged through a microscope, the image formed onto the charge coupled device element consists of contributions from all layers. If a bubble is larger than the depth of focus, the part of the bubble above the focal plane influences the image formation and therefore the bubble size measured. Thus, this thesis presents a methodology to compute two-dimensional image formation from three-dimensional objects, hollow spheres and find under which circumstances the optical image formation leads to a significant deviation in measurement of the actual size
Incoherent synchrotron emission of laser-driven plasma edge
Creators: name: Serebryakov, D. A.
name: Nerush, E. N.
name: Kostyukov, I. Yu.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: When a relativistically intense linearly polarized laser pulse is incident on an overdense plasma, a dense electron layer is formed on the plasma edge which relativistic motion results in high harmonic generation, ion acceleration and incoherent synchrotron emission of gamma-photons. Here we present a self-consistent analytical model that describes the edge motion and apply it to the problem of incoherent synchrotron emission by ultrarelativistic plasma electrons. The model takes into account both coherent radiation reaction from high harmonics and incoherent radiation reaction in the Landau-Lifshitz form. The analytical results are in agreement with 3D particle-in-cell simulations in a certain parameter region that corresponds to the relativistic electronic spring interaction regime.
Open Systems' Density Matrix Properties in a Time Coarsened Formalism
Creators: name: Englman, Robert
name: Yahalom, Asher
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The concept of time-coarsened density matrix for open systems has frequently featured in equilibrium and non-equilibrium statistical mechanics, without being probed as to the detailed consequences of the time averaging procedure. In this work we introduce and prove the need for a selective and non-uniform time-sampling, whose form depends on the properties (whether thermalized or not) of the bath. It is also applicable when an open microscopic sub-system is coupled to another {\it finite} system. By use of a time-periodic minimal coupling model between these two systems, we present detailed quantitative consequences of time coarsening, which include initial state independence of equilibration, deviations from long term averages, their environment size dependence and the approach to classicality, as measured by a Leggett-Garg type inequality. An interacting multiple qubit model affords comparison between the time integrating procedure and the more conventional environment tracing method.
description: 21 pages, 7 figures; Foundations of Physics, published online 14 April 2015
Ethical Considerations for Randomized Controlled Trials with Low-Income Students
Creators: name: Foster, Peter
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Randomized controlled trials are widely employed in K-12 education to test the efficacy of new programs and curriculums before rollout. Many of these programs target the academic outcomes of low-income students. However, unlike their peers in the biomedical sphere, researchers designing these trials do not have access to sufficient ethical guidelines, as those written specifically education do not exist.
	To examine what ethical research guidelines specific to education RCTs with low-income K-12 students should look like, as well as how current research measures up to these guidelines, this thesis employs a two-prong approach. Firstly, a critical ethics analysis was conducted, pulling from existing ethics writing and noneducation research guidelines to determine what ethical dilemmas are unique to education RCTs and how to address them. Then a systematic review was conducted, including all relevant K-12 education RCTs published in the United States over the past five years, to highlight current research trends and assess how ethical issues have been addressed recently. Four papers from the review were pulled and used as case studies to illustrate ethical concerns and considerations in practice. Both the critical ethics analysis and systematic review are the first of their kinds in the field.
	The analysis revealed a number of ethical concerns unique to education in regards to low-income students, policy equipoise, consent, fair selection, and intra-school competition. The review showed that many of these concerns are not widely addressed. The combined results illustrate the need for standardized ethical guidelines for K-12 education research.
Nyctinomops aurispinosus Peale 1848
Creators: name: Wilson, Don E.
name: Mittermeier, Russell A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Molossidae
Nyctinomops
Nyctinomops aurispinosus

description: 43. Peale’s Free-tailed Bat Nyctinomops aurispinosus French: Nyctinomope de Peale / German: Peale-Bulldogfledermaus / Spanish: Nycténimo de Peale Taxonomy. Dysopes aurispinosus Peale, 1848, “flew on board the U. S. Ship Peacock, off the coast of Brazil... about one hundred miles [= 161 km] from land, south of Cape St. Roque,” state of Rio Grande do Norte, Brazil. This species is monotypic. Distribution. Patchily from N Mexico (S Sonora and S Tamaulipas) to SW Honduras, W Colombia, N Venezuela, W & SE Peru, WC & SE Boliva, and E & SE Brazil; it may occur in Ecuador. Descriptive notes. Head-body 63-73 mm, tail 41-565 mm, ear 18-25 mm, hindfoot 8-12 mm, forearm 47-53 mm; weight 13-23 g. Short (c. 4 mm) dense fur can be reddish to grayish brown on back, with whitish bases; paler on underside. Ears are large, wrinkled, and connected above base in front with spiny projections on medial edge. Lips are wrinkled and large. Wings and tail membrane are dark brown. Basisphenoid pits are shallow. Teeth are robust, with M* even with posterior edge of hard palate. Posterointernal cingula of M| and M, are rounded. Dental formula for all members of Nyctinomopsis 11/2, C1/1,P2/2,M 3/3 (x2) = 30. Chromosomal complement has 2n = 48 and FN = 58. Habitat. Dry tropical regions, including thorn forest, scrubland, deciduousforest, and urban areas. Elevational range is from sea level to 3150 m, but most records are from below 1000 m. Food and Feeding. Peale’s Free-tailed Bat is an insect-feeder, probably taking moths (Lepidoptera) and other soft-bodied insects, based on diet of congenerics and morphological study of the jaw. Breeding. Lactating females were documented in February from Peru, and July from Mexico. In Bolivia, pregnant females have been found in September. Activity patterns. Small groups of Peale’s Free-tailed Bats have been found roosting in caves and in the attic of a house. In north-eastern Mexico, cranial remains of this species have been found in owl pellets. Movements, Home range and Social organization. Peale’s Free-tailed Bat has been found roosting with other species of Nyctinomops, including the Broad-eared Freetailed Bat (N. laticaudatus) and the Big Free-tailed Bat (N. macrotis). Status and Conservation. Classified as Least Concern on The IUCN Red Lust. Bibliography. Arita (2014b), Bianconi et al. (2009), Carter & Davis (1961), Eger (2008), Espinal et al. (2016), Freeman (1979), Ibanez & Ochoa (1989), Jones & Arroyo-Cabrales (1990), Taddei & Garutti (1981), Warner et al. (1974).
description: Published as part of Don E. Wilson & Russell A. Mittermeier, 2019, Molossidae, pp. 598-672 in Handbook of the Mammals of the World – Volume 9 Bats, Barcelona :Lynx Edicions on page 637, DOI: 10.5281/zenodo.6418279
Identifying Functional Thermodynamics in Autonomous Maxwellian Ratchets
Creators: name: Boyd, A. B.
name: Mandal, D.
name: Crutchfield, J. P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Dynamical Systems (math.DS)
subject: Chaotic Dynamics (nlin.CD)
subject: Biological Physics (physics.bio-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We introduce a family of Maxwellian Demons for which correlations among information bearing degrees of freedom can be calculated exactly and in compact analytical form. This allows one to precisely determine Demon functional thermodynamic operating regimes, when previous methods either misclassify or simply fail due to approximations they invoke. This reveals that these Demons are more functional than previous candidates. They too behave either as engines, lifting a mass against gravity by extracting energy from a single heat reservoir, or as Landauer erasers, consuming external work to remove information from a sequence of binary symbols by decreasing their individual uncertainty. Going beyond these, our Demon exhibits a new functionality that erases bits not by simply decreasing individual-symbol uncertainty, but by increasing inter-bit correlations (that is, by adding temporal order) while increasing single-symbol uncertainty. In all cases, but especially in the new erasure regime, exactly accounting for informational correlations leads to tight bounds on Demon performance, expressed as a refined Second Law of Thermodynamics that relies on the Kolmogorov-Sinai entropy for dynamical processes and not on changes purely in system configurational entropy, as previously employed. We rigorously derive the refined Second Law under minimal assumptions and so it applies quite broadly---for Demons with and without memory and input sequences that are correlated or not. We note that general Maxwellian Demons readily violate previously proposed, alternative such bounds, while the current bound still holds.
description: 13 pages, 9 figures, http://csc.ucdavis.edu/~cmg/compmech/pubs/mrd.htm
Epidemiology, risk factors and outcomes of rheumatic toxicities of immune checkpoint inhibitors in patients with advanced melanoma
Creators: name: Bruce, Alana
Publisher: name: Macquarie University
Year: 2023
Subjects: Other education not elsewhere classified

description: Aim  To estimate the frequency of rheumatic toxicities of immune checkpoint inhibitors (ICI) in patients with advanced melanoma and to identify risk factors and potential predictors of outcomes. Method  A single-centre observational study of patients with stage III or IV melanoma receiving all available ICI therapies, who completed a for-purpose questionnaire to capture rheumatic symptoms upon recruitment and at 12-months. Clinical details were extracted from patients’ medical records. Potential predictors of rheumatic toxicities and cancer outcomes were identified through regression analysis. Results  Amongst 147 eligible patients, the prevalence of new or worsening rheumatic symptoms was 32.5% at recruitment and 21% at 12 months. The incidence of documented arthralgia, inflammatory arthritis and PMR-like syndrome were 39.5%, 5.4% and 3.4% respectively. Binary logistic regression identified pre-existing symptomatic rheumatic disease, including non-immune mediated rheumatic disease, as the primary risk factor for developing rheumatic toxicities (OR 3.16, 95% CI 1.36 – 7.34). Continuation of ICI therapy (OR 16.5, 95% CI 2.53 – 107.70), followed by rheumatic toxicities (OR = 14.2, 95% CI 1.45 – 138.62) were variables associated with favourable tumour response. Conclusion  Rheumatic toxicities of ICI therapy commonly affect patients with melanoma and are more likely to occur in patients with pre-existing autoimmune and non-immune mediated rheumatic disease, especially when symptomatic prior to commencing treatment. Rheumatic toxicities are associated with favourable tumour responses.
The Hispanic Health Paradox, as it Relates to Cardiovascular Disease
Creators: name: Stouffer, Joy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: 
The Hispanic health paradox (HHP) is an epidemiological paradox that describes the observation that the Hispanic population in the United States tends to have better health outcomes than would be expected, given the socioeconomic profile of this population. As a clear correlation between socioeconomic status (SES) and health outcomes has been established, one would expect the Hispanic population to have relatively poorer outcomes than the non-Hispanic (NH) white population and comparable outcomes to the NH black population. Among other health outcomes, the HHP has been observed with respect to cardiovascular disease (CVD), as analyses by the American Heart Association and Centers for Disease Control have shown that the Hispanic population has a lower prevalence of CVD than the NH white and NH black populations. However, some smaller studies challenge the existence of the HHP. Additionally, the impact of CVD risk factors (such as diabetes) and level of acculturation to the United States on the HHP is understudied. By utilizing data from the 2018 National Health Interview Survey, this thesis will support the existing literature that shows that the HHP is found with respect to CVD. I will also argue that the HHP with respect to CVD is present among populations with diabetes but to a lesser extent than within the general population. This suggests that the prevalence of CVD among Hispanic individuals in the general population may be artificially low due to lack of health care utilization. Finally, I will argue that the HHP is present among both U.S.-born and foreign-born populations, indicating that the high proportion of immigrants in the Hispanic population and “healthy immigrant selection” are not enough to account for the paradox.
Sorszintű Java sérülékenység detektor megalkotása
Creators: name: Vándor, Norbert
Publisher: name: Zenodo
Year: 2023

description: A mai társadalmunk nagyban függ a különböző informatikai rendszerektől. Éppen ezért
 nemcsak kívánatos, hanem létfontosságú is a szoftverek magas minősége és biztonsága.
 A szoftverfejlesztőket segítik a különböző empirikus megoldások, amik a gazdag
 nyílt forráskódú adatokra és a gépi tanulási módszerek adatfeldolgozására támaszkodnak.
 Ennek ellenére a legkorszerűbb hiba- és sérülékenység-kereső technikákat meglehetősen
 kevés helyen alkalmazzák. Ez főként az alacsony részletességnek (az előrejelzés például
 fájlszintű) és a megmagyarázhatóság hiányának (nem tudjuk, miért jelölt a rendszer)
 köszönhető.
 A dolgozat célja egy olyan eszköz létrehozása és bemutatása, ami hatékonyan képes
 Java rendszerekben sérülékenységek detektálására. Ezen felül az is a cél, hogy mindezt
 kellő részletességgel (pontosabban sorszinten) és megmagyarázhatóan tegye. Az előbbi
 tulajdonsága lehetővé teszi, hogy a fejlesztők gyorsabban nekiláthassanak a hibák javításához,
 mivel nagyban csökkenti a hibák pontos helyének keresését, az utóbbi tulajdonság
 pedig segít az előrejelzés helyességének bizonyításában.
 A dolgozat eredményeiből publikáció is született az ICCSA nemzetközi konferencián.
Mass generation via the Higgs boson and the quark condensate of the QCD vacuum
Creators: name: Schumacher, Martin
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Higgs boson, recently discovered with a mass of 125.09$\pm$0.24 GeV is known to mediate the masses of elementary particles, but only 2% of the mass of the nucleon. Extending a previous investigation [1] and including the strange-quark sector, hadron masses are derived from the quark condensate of the QCD vacuum and from the effects of the Higgs boson. These calculations include the $π$ meson, the nucleon and the scalar mesons $σ(600)$, $κ(800)$, $a_0(980)$ $f_0(980)$ and $f_0(1370)$. The predicted second $σ$ meson $σ'(1344)=|s\bar{s}\rangle$, is investigated and identified with the $f_0(1370)$ meson. An outlook is given on the hyperons $Λ$, $Σ^{0,\pm}$ and $Ξ^{0,-}$.
description: 18 pages, 2 figures
pylogeny of Bambusoideae based on the transcriptome and chloroplast genome Raw sequence reads
Creators: name: BGI
Publisher: name: CNGB
Year: 2018
Subjects: raw sequence reads
Multispecies

description: sequecing transcriptome and chloroplast of 387 woody bamboos representing in 15 clades in Asia and a fully resolved phylogenetic tree derived from protein-coding genes and LSC regions.
Weighing of the Dark Matter at the Center of the Galaxy
Creators: name: Dokuchaev, V. I.
name: Eroshenko, Yu. N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: A promising method for measuring the total mass of the dark matter near a supermassive black hole at the center of the Galaxy based on observations of nonrelativistic precession of the orbits of fast S0 stars together with constraints on the annihilation signal from the dark matter particles has been discussed. An analytical expression for the precession angle has been obtained under the assumption of a power-law profile of the dark matter density. In the near future, modern telescopes will be able to measure the precession of the orbits of S0 stars or to obtain a strong bound on it. The mass of the dark matter necessary for the explanation of the observed excess of gamma radiation owing to the annihilation of the dark matter particles has been calculated with allowance for the Sommerfeld effect.
description: 5 pages, 3 figures
Hola, soy intérprete: An Examination of the Roles of Medical Interpreters
Creators: name: Shiba, Jillian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: The United States is an increasingly multicultural society, where there is a growing number of people who do not speak English as their first language, or who have limited English proficiency. Medical interpreters are a vital resource to be able to provide these individuals with their legal right to health care access in their language of preference. This thesis evaluates the general roles of medical interpreters and examines the nature of their various roles outside of strict interpretation through investigating the relationship between interpreters and providers, the relationship between interpreters and patients, and the interpreter roles of a cultural broker and a patient advocate. This research was conducted through about eighteen hours of shadowing individual Spanish-English medical interpreters at a large public teaching hospital and through interviews with eight Spanish-English interpreters from this hospital. The findings of this thesis suggest that the structure of the hospital system and the rules of the department constrain the interpreters from fully being able to provide the best care possible to the patients.
The p-adic Gross-Zagier formula on Shimura curves
Creators: name: Disegni, Daniel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11G40

description: We prove a general formula for the $p$-adic heights of Heegner points on modular abelian varieties with potentially ordinary (good or semistable) reduction at the primes above $p$. The formula is in terms of the cyclotomic derivative of a Rankin-Selberg $p$-adic $L$-function, which we construct. It generalises previous work of Perrin-Riou, Howard, and the author, to the context of the work of Yuan-Zhang-Zhang on the archimedean Gross-Zagier formula and of Waldspurger on toric periods. We further construct analytic functions interpolating Heegner points in the anticyclotomic variables, and obtain a version of our formula for them. It is complemented, when the relevant root number is $+1$ rather than $-1$, by an anticyclotomic version of the Waldspurger formula. When combined with work of Fouquet, the anticyclotomic Gross-Zagier formula implies one divisibility in a $p$-adic Birch and Swinnerton-Dyer conjecture in anticyclotomic families. Other applications described in the text will appear separately.
description: 75 pages. The present version is identical to the previous one (and to the published version), except for footnotes signalling that the main theorem is off by a factor of 2. A list of errata is contained in the author's "The p-adic Gross-Zagier formula on Shimura curves, II", Appendix B
Progressive multiple sequence alignment with the Poisson Indel Process
Creators: name: Maiolo, Massimo
name: Zhang, Xiaolei
name: Gil, Manuel
name: Anisimova, Maria
Publisher: name: Selbstverlag
Year: 2017
Subjects: 510: Mathematik
572: Biochemie

description: Sequence alignment lies at the heart of many evolutionary and comparative genomics studies. However, the optimal alignment of multiple sequences is NP-hard, so that exact algorithms become impractical for more than a few sequences. Thus, state of the art alignment methods employ progressive heuristics, breaking the problem into a series of pairwise alignments guided by a phylogenetic tree. Changes between homologous characters are typically modelled by a continuous-time Markov substitution model. In contrast, the dynamics of insertions and deletions (indels) are not modelled explicitly, because the computation of the marginal likelihood under such models has exponential time complexity in the number of taxa. Recently, Bouchard-Côté and Jordan [PNAS (2012) 110(4):1160-1166] have introduced a modification to a classical indel model, describing indel evolution on a phylogenetic tree as a Poisson process. The model termed PIP allows to compute the joint marginal probability of a multiple sequence alignment and a tree in linear time. Here, we present an new dynamic programming algorithm to align two multiple sequence alignments by maximum likelihood in polynomial time under PIP, and apply it a in progressive algorithm. To our knowledge, this is the first progressive alignment method using a rigorous mathematical formulation of an evolutionary indel process and with polynomial time complexity.
Evolution of a Passive Tracer in Capillaries with Triangular Cross-Sectional Geometries
Creators: name: Hobson, Gabrielle
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020
Subjects: subject: Mathematics
subject: FOS: Mathematics
subject: Fluid dynamics

description: In this work we investigate the effect of triangular cross-sectional geometries on the evolution of a passive tracer injected in a capillary subject to laminar background flow. The role of the cross-sectional geometry in determining the skewness of the tracer concentration distribution at short and long times is of particular interest, as skewness is a measure of the asymmetries of the distribution. We report experimental observations of the evolution of a passive tracer injected in an equilateral triangle capillary and compare them to numerical simulations. We also present theoretical methods to solve a Poisson's problem for Stokes flow in an equilateral capillary using complex variables techniques. We extend our work to isosceles triangle geometries and numerically solve Poisson's problem using the finite elements method in varying isosceles triangle domains. These results show a change in the loading behavior of a passive tracer in capillaries with isosceles triangle cross-sections, corresponding to a sign-change in the skewness from positive to negative.
Animal detection and species classification on Swiss camera trap images using AI
Creators: name: Vidondo, Beatriz
name: Glüge, Stefan
name: Hubert, Laurtent
name: Fischer, Claude
name: Le Grand, Luc
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Object detection
Computer vision
006: Spezielle Computerverfahren
590: Tiere (Zoologie)

description: Motion-triggered camera traps are essential for the monitoring and management of wildlife. As per today in Switzerland, a high number of pictures is manually processed (annotated and classified). We study the utilization of available detection and classification models to (semi-)automatize this process. Two main aspects were investigated: 1) evaluate the feasibility of a non-expert local application (with Microsoft's MegaDetector model), and 2) quantify model performance using several labelled datasets of varying quality and content. Our results show a highly accurate (sensitive and specific), and reliable, fast inference which efficiently allows the automatic pre-discarding of all non-animal images. Further, the MegaDetector turns out to be both, user-friendly and highly performant and thus, an ideal tool for Swiss wildlife experts and stakeholders. Incentives (educational and financial) are required to promote knowledge transfer to this field.
Educational Needs for the Nurse Caring for the Dying Pediatric Patient
Creators: name: Davidson, Rebecca
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Pediatric hospice and palliative care are aimed at improving the quality of life for dying children and their families. It is family-centered care that requires the management of end-of-life symptoms, compassionate communication skills with the patient and the family, and self-care of the nurse caring for the child. The need for education is apparent, as most children who could benefit from end-of-life care do not receive it. This may be due to unpredictable health outcomes of children, reluctance of parents to participate, or the refusal of end-of-life care. Despite these barriers, symptom management should be specialized for pediatric patients, with a focus on comfort rather than cure. Communication requires skill by the nurse, with a focus on quality of life, creating lasting memories, recognizing the child’s development level, and supporting bereavement of families. Self-care activities, such as unrelated hobbies and debriefing sessions, are needed to promote resilience in staff and prevent burnout. With baseline knowledge about these aspects of pediatric end-of-life care, the nurse is well-qualified to care for the dying child at the bedside and support the family. The purpose of this paper is to give an overview of pediatric end-of-life care for nurses in hospital settings caring for hospice and palliative care pediatric patients.
A generalization of Livingston's coefficient inequalities for functions with positive real part
Creators: name: Efraimidis, Iason
Publisher: name: arXiv
Year: 2015
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 30C45, 30C50

description: For functions $p(z) = 1 + \sum_{n=1}^\infty p_n z^n$ holomorphic in the unit disk, satisfying $ {\rm Re}\, p(z) > 0$, we generalize two inequalities proved by Livingston in 1969 and 1985, and simplify their proofs. One of our results states that $|p_n -w p_k p_{n-k}|\leq 2\max\{1, |1-2w|\}, w\in\mathbb{C}$. Another result involves certain determinants whose entries are the coefficients $p_n$. Both results are sharp. As applications we provide a simple proof of a theorem of J.E. Brown and various inequalities for the coefficients of holomorphic self-maps of the unit disk.
description: 12 pages, LaTeX; An alternative proof of Theorem 2 and an alternative proof of a theorem of Brown are added in version 2. Available online in Journal of Mathematical Analysis and Applications
GEOTECHNICAL INVESTIGATION ON ENGINEERING PROPERTIES OF SOIL FOUND IN GUDER TOWN
Creators: name: EYERUSALEM TADESSE ABEBE
Publisher: name: Zenodo
Year: 2021

description: A soils investigation is an essential part of the design and construction of a proposed building or infrastructure. Guder is a town in western Ethiopia, 123 km from Addis Abeba. The objective of this research is to investigate the engineering properties of the soils found in the Guder town for better design and construction of civil engineering projects in the town. To achieve its objective samples from different parts of the town were collected and laboratory tests were done on the collected samples. The result of Atterberg limits test results of soils found in Guder town is liquid limit ranging between 19.02 - 103.81%, plastic limit 0 -42.93 % and Plasticity index 2.35 – 64.52 %. The specific gravity test results are 2.33 – 3. The values are higher than the specific gravity of the temperate zone soils, which is about 2.65 -2.70. Grain size analysis test results that, the soil in Guder town is mostly silty and silty sand. In which the soil of the town has fine fraction 9.4 to 88.4%, sand fraction 11 to 55.4 % and gravel fraction 0.6 to 47.8 %. Based on AASHTO soil classification system the soil categorized under group A-2-4, A-2.7, A7-5 and A-7-6. Soil type A2-4 and A-2-7 Excellent quality and suitable for using as sub grade soil. But the other groups are poor quality and not suitable for sub grade material. Based on USCS soil classification system the soil categorized under group SC, MH, SM, GC, CH, and GM, most of the soil lies above A-line, it implies that the soil is inorganic clay with high plasticity, the remain is lies below A-line, which is organic silt with low plasticity. As determined from the one-dimensional consolidation test conducted on undisturbed soil samples, compression index (Cc) ranges from 0.47 -0.63, coefficient of consolidation (Cv) ranges from 0.006 -0.206 cm2 /min, coefficient of permeability (k) ranges from 0.19 -23.42 cm/sec. From Unconsolidated undrained triaxial shear test result undrained cohesion ranges from 31.4 – 68.5 KN/m2 . For this test the more circle envelop is curved and fall above the φ = 0 line with (φ = 6.56 – 11.31).