cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Computer-aided drug design of activators of the cardiac Kv7.1 potassium channel
Creators: name: Castro Gonzalez, Laura Maria
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Long QT syndrome
subject: Heart disease
subject: Kv7.1 ion channel
subject: Computer-aided drug design
subject: Virtual screening
subject: Polyunsaturated fatty acids
subject: Endocannabinoids
subject: Education--Sciences
subject: Education--Health

description: Long QT syndrome is a heart disease that ends the lives of numerous children and young adults every year. This condition is triggered by the malfunction of some ion channels, including the voltage-gated potassium Kv7.1. In this thesis, multiple computational tools were employed to identify compounds that potentiate the activity of this ion channel. First, a Kv7.1 computational model was created from the Xenopus laevis structure. Then, suitable binding sites in the channel were identified using libraries of known activators of the channel: polyunsaturated fatty acids and endocannabinoids. Selected sites were in silico screened against a large library of small molecules. Multiple criteria such as binding energies, bioavailability and selectivity were employed to finally select compounds for experimental evaluation. This work identified two compounds with high potency and specificity for each binding site studied in the Kv7.1 channel.
Digital Singularisation
Creators: name: Pirogan, Marc
Publisher: name: Zenodo
Year: 2019
Subjects: digitisation
singularisation
social change

description: According to Andreas Reckwitz, we are living in a time of fundamental social change — our society is becoming a society of singularisation. Digitisation is playing a pivotal role in this process. But what exactly does singularisation mean? And what consequences  will it have for the constitution of our society? Marc Pirogan takes a look back at his lecture.
Additional file 2 of Small RNA profiling for identification of microRNAs involved in regulation of seed development and lipid biosynthesis in yellowhorn
Creators: name: Wang, Li
name: Ruan, Chengjiang
name: Bao, Aomin
name: Li, He
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Table S2. Distribution of small RNAs among different categories in LO yellowhorn.
Development of inhibitors of alternative splicing events crucial to HIV-1 replication : a new anti-HIV/AIDS strategy targeting the host cell machinery
Creators: name: Bandy, Laura Elizabeth
Publisher: name: University of British Columbia
Year: 2014

description: Introduction : HIV infects over 35 million people worldwide . Since the introduction of HAART the survival rate for HIV/AIDS patien ts has increased exponentially. HAART, although effective , does have long term limitations resulting from cross resistance to c ertain drugs of the same class , compliance, and side effects ; therefore , investigating alternative avenues and targets for therapeutic treatment is vital . Through compound library screening, IDC16, a tetracyclic indole compound , has been identified as an inhibitor of SR protein splicing factor 1 ( SRSF1). This protein play s a redundant role in human splicing but is specifically used in HIV - 1 infected cell alternative splicing. Blocking HIV - 1 alternative splicing through inhibitio n of SRSF1 function may establish a novel strategy for HIV/AIDS therapy and is advantageous because it (i) targets a protein that is essential to HIV replication, (ii) targets a huma n protein potentially eliminating the chances of mutation and subsequent r esistance to drug therapy . Although IDC16 displays cytotoxicity, the design of mimics of IDC16 could allow for the discovery of an equally or more potent compound w hich eliminates the cytotoxic effects. Hypothesis : The synthesis of appropriately functionalized and conformation ally mobile ring opened mimics of IDC16 will lead to the identification of new HIV replication inhibitors that : target SRSF1 ; are not cytotoxic ; do not intercalate DNA ; and retain similar or superior anti - HIV activity when compared to IDC16 . Objectives : The synthesi s and evaluation of the anti - HIV activity of a library of IDC16 mimics corresponding to different structural types from a common 2 - pyridinone scaffold: 1 ) bisheterocyclic amides, 2 ) bisheterocyclic oxadiazoles, 3 ) fused bishet erocyclic isoxazolidin - 7 - ones , 4 ) fused bisheterocyclic 5 - arylpyrazolidin - 7 - ones and 5 ) C - 4 (hetero)aryl substituted 2 - pyridinones . Results: Our effort to synthesize inhibitors of HIV - 1 by creating a library of IDC16 mimics led to the discovery of DGPS39/LB - 45 . This compound was 90% as effective as the HAART drug AZT in blocking HIV - 1 replication. Significance : Creating a non - cytotoxic IDC16 mi mic with the same or greater affinity for the target protein SRSF1 will allow for further investigation int o a novel treatment of HIV/AIDS ; which has the potential to circumvent the problems with viral resistance experienced with HAART.
Irreversibilities and efficiency at maximum power of heat engines: illustrative case of a thermoelectric generator
Creators: name: Apertet, Y.
name: Ouerdane, H.
name: Goupil, C.
name: Lecoeur, Ph.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: Thermoelectric generators are particularly suitable to investigate the irreversible processes which govern the coupled transport of matter and heat in solid-state systems. We study the efficiency at maximum power in the strong coupling regime, where the thermal flux is proportionnal to the electrical current inside the generator. We demonstrate that depending on the source of irreversibility we obtain either the Curzon-Ahlborn efficiency for external dissipation or a universal efficiency at maximum power for internal dissipation. A continuous change between these two extremes is evidenced. Effects of dissymetry of thermal contact conductance are also investigated.
description: 5 pages, 3 figures, accepted for publication in Phys. Rev. E
On the number of ergodic physical/SRB measures of singular-hyperbolic attracting sets
Creators: name: Araujo, Vitor
Publisher: name: arXiv
Year: 2022
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37D25 (Primary), 37D30, 37D20 (Secondary)

description: It is known that sectional-hyperbolic attracting sets, for a $C^2$ flow on a finite dimensional compact manifold, have at most finitely many ergodic physical invariant probability measures. We prove an upper bound for the number of distinct ergodic physical measures supported on a connected singular-hyperbolic attracting set for a $3$-flow. This bound depends only on the number of Lorenz-like equilibria contained in the attracting set. Examples of singular-hyperbolic attracting sets are provided showing that the bound is sharp.
description: 31 pages, 13 figures
Generating Two-dimensional Ferromagnetic Charge Density Waves via External Fields
Creators: name: Jin, Heng
name: Chen, Jiabin
name: Li, Yang
name: Shao, Bin
name: Huang, Bing
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Two-dimensional (2D) ferromagnetic charge density wave (CDW), an exotic quantum state for exploring the intertwining effect between correlated charge and spin orders in 2D limit, has not been discovered in the experiments yet. Here, we propose a feasible strategy to realize 2D ferromagnetic CDWs under external fields, which is demonstrated in monolayer VSe$_2$ using first-principles calculations. Under external tensile strain, two novel ferromagnetic CDWs ($\sqrt{3}$$\times$$\sqrt{3}$ and 2$\times2\sqrt{3}$ CDWs) can be generated, accompanied by distinguishable lattice reconstructions of magnetic V atoms. Remarkably, because the driving forces for generating these two ferromagnetic CDWs are strongly spin-dependent, fundamentally different from that in conventional CDWs, the $\sqrt{3}$$\times$$\sqrt{3}$ and 2$\times2\sqrt{3}$ CDWs can exhibit two dramatically different half-metallic phases under a large strain range, along with either a flat band or a Dirac cone around Fermi level. Our proposed strategy and material demonstration may open a door to generate and manipulate correlation effect between collective charge and spin orders via external fields.
description: 6 pages,4 figures
Transit Timing Observations from Kepler: VI. Transit Timing Variation Candidates in the First Seventeen Months from Polynomial Models
Creators: name: Ford, Eric B.
name: Ragozzine, Darin
name: Rowe, Jason F.
name: Steffen, Jason H.
name: Barclay, Thomas
name: Batalha, Natalie M.
name: Borucki, William J.
name: Bryson, Stephen T.
name: Caldwell, Douglas A.
name: Fabrycky, Daniel C.
name: Gautier, Thomas N.
name: Holman, Matthew J.
name: Ibrahim, Khadeejah A.
name: Kjeldsen, Hans
name: Kinemuchi, Karen
name: Koch, David G.
name: Lissauer, Jack J.
name: Still, Martin
name: Tenenbaum, Peter
name: Uddin, Kamal
name: Welsh, William
Publisher: name: arXiv
Year: 2012
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Transit timing variations provide a powerful tool for confirming and characterizing transiting planets, as well as detecting non-transiting planets. We report the results an updated TTV analysis for 1481 planet candidates (Borucki et al. 2011; Batalha et al. 2012) based on transit times measured during the first sixteen months of Kepler observations. We present 39 strong TTV candidates based on long-term trends (2.8% of suitable data sets). We present another 136 weaker TTV candidates (9.8% of suitable data sets) based on excess scatter of TTV measurements about a linear ephemeris. We anticipate that several of these planet candidates could be confirmed and perhaps characterized with more detailed TTV analyses using publicly available Kepler observations. For many others, Kepler has observed a long-term TTV trend, but an extended Kepler mission will be required to characterize the system via TTVs. We find that the occurrence rate of planet candidates that show TTVs is significantly increased (~68%) for planet candidates transiting stars with multiple transiting planet candidate when compared to planet candidates transiting stars with a single transiting planet candidate.
description: Accepted to ApJ; 9 pages, incl. 3 B&W figures, 1 table, 2 electronic datasets available as ancillary files; Includes analyses of more planet candidates; Transit times and additional figures at http://www.astro.ufl.edu/~eford/data/kepler/
Wrestling With Religion: Freedom, Violence, and Ultimate Concern on the Theodramatic Stage
Creators: name: Fieseler, Nicholas Leroy
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Theodrama
subject: Implicit Religion
subject: Mimetic Theory
subject: Professional Wrestling
subject: Ultimate Concern
subject: Education--Religious

description: The intersection of religion and popular culture is largely understood as imposing traditional forms of religion onto popular culture phenomena. This conception restricts the role of religion to preconceived and formalized expressions of belief systems without recognizing the potentially vast expanse the concept of religion entails. By applying the models of Hans Urs von Balthasar’s theodrama and Rene Girard’s mimetic theory to popular culture, the distinction between areas deemed sacred and profane is diminished, making it possible to re-imagine aspects of religion in all areas of existence. This thesis explores religion implicit in the oft-ignored phenomenon of professional wrestling, through which a fresh understanding of moral behavior, and the appeal of “bad” actors on the theodramatic and wrestling stage, may be seen as expressions of religion discerned independent of formalized definitions and traditional restrictions. In this theodramatic re-imagining, the category of religion expands beyond its current narrow confines to include areas not normally deemed religious.
Vision-Based Navigation I: A navigation filter for fusing DTM/correspondence updates
Creators: name: Kupervasser, Oleg
name: Voronov, Vladimir
Publisher: name: arXiv
Year: 2011
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences
subject: E.5; E.4; E.2; H.1.1; F.1.1; F.1.3
subject: 68T45

description: An algorithm for pose and motion estimation using corresponding features in images and a digital terrain map is proposed. Using a Digital Terrain (or Digital Elevation) Map (DTM/DEM) as a global reference enables recovering the absolute position and orientation of the camera. In order to do this, the DTM is used to formulate a constraint between corresponding features in two consecutive frames. The utilization of data is shown to improve the robustness and accuracy of the inertial navigation algorithm. Extended Kalman filter was used to combine results of inertial navigation algorithm and proposed vision-based navigation algorithm. The feasibility of this algorithms is established through numerical simulations.
description: 26 pages, 3 figures, in English and in Russian. arXiv admin note: substantial text overlap with arXiv:1106.6341, arXiv:1107.1470
Interpretable Battery Cycle Life Range Prediction Using Early Degradation Data at Cell Level
Creators: name: Zhang, Huang
name: Su, Yang
name: Altaf, Faisal
name: Wik, Torsten
name: Gros, Sebastien
Publisher: name: arXiv
Year: 2022
Subjects: subject: Systems and Control (eess.SY)
subject: Machine Learning (cs.LG)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Battery cycle life prediction using early degradation data has many potential applications throughout the battery product life cycle. For that reason, various data-driven methods have been proposed for point prediction of battery cycle life with minimum knowledge of the battery degradation mechanisms. However, managing the rapidly increasing amounts of batteries at end-of-life with lower economic and technical risk requires prediction of cycle life with quantified uncertainty, which is still lacking. The interpretability (i.e., the reason for high prediction accuracy) of these advanced data-driven methods is also worthy of investigation. Here, a Quantile Regression Forest (QRF) model, having the advantage of not assuming any specific distribution of cycle life, is introduced to make cycle life range prediction with uncertainty quantified as the width of the prediction interval, in addition to point predictions with high accuracy. The hyperparameters of the QRF model are optimized with a proposed alpha-logistic-weighted criterion so that the coverage probabilities associated with the prediction intervals are calibrated. The interpretability of the final QRF model is explored with two global model-agnostic methods, namely permutation importance and partial dependence plot.
Two quantum walkers sharing coins
Creators: name: Xue, Peng
name: Sanders, Barry C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider two independent quantum walks on separate lines augmented by partial or full swapping of coins after each step. For classical random walks, swapping or not swapping coins makes little difference to the random walk characteristics, but we show that quantum walks with partial swapping of coins have complicated yet elegant inter-walker correlations. Specifically we study the joint position distribution of the reduced two-walker state after tracing out the coins and analyze total, classical and quantum correlations in terms of the mutual information, the quantum mutual information, and the measurement-induced disturbance. Our analysis shows intriguing quantum features without classical analogues.
description: 10 pages, 4 figures
Banach gradient flows for various families of knot energies
Creators: name: Matt, Hannes
name: Steenebrügge, Daniel
name: von der Mosel, Heiko
Publisher: name: arXiv
Year: 2022
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Differential Geometry (math.DG)
subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 53E99, 49Q10 (Primary) 49J50, 53A04, 57K10 (Secondary)

description: We establish long-time existence of Banach gradient flows for generalised integral Menger curvatures and tangent-point energies, and for O'Hara's self-repulsive potentials $E^{α,p}$. In order to do so, we employ the theory of curves of maximal slope in slightly smaller spaces compactly embedding into the respective energy spaces associated to these functionals, and add a term involving the logarithmic strain, which controls the parametrisations of the flowing (knotted) loops. As a prerequisite, we prove in addition that O'Hara's knot energies $E^{α,p}$ are continuously differentiable.
description: 42 pages
Manufacture, Refinement and Low-Speed Flight Testing of a Small-Scale, High-Speed Uncrewed Aerial Vehicle
Creators: name: Gair, Shaun Robert
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: UAV
subject: Flight Test
subject: Vertical Tail
subject: Lateral Stability
subject: High Speed
subject: Delta Wing
subject: Engineering--Aerospace
subject: Engineering--Mechanical

description: This thesis details the mechanical design, manufacture, and flight testing of a sub-2.5kg UAV prototype. While the aircraft configuration is designed for supersonic flight, the goal of this work is to evaluate the low-speed flight characteristics and to prove positive stability and control at low speeds. Low-speed testing will evaluate the applicability of established design techniques---developed for full-scale, crewed aircraft---to small-scale, high-speed UAVs. Review of literature and preliminary results led to a focus on the prediction of lateral stability characteristics, especially vertical tail volume coefficient (VTVC). Flight testing of the prototype did not yield sustained flight; however, data collected during takeoff attempts provide valuable information about the behaviour of the design. These data indicate that the aircraft was laterally unstable, contradicting the vertical tail design determined from VTVC sizing methods. Analysis of VTVC for existing tailless delta-winged aircraft and comparison with the MUFASA aircraft showed that VTVC is insufficient as an early design parameter for small-scale, high-speed designs. A novel parameter, the fuselage-normalized tail volume coefficient, is proposed for use in conjunction with the conventional VTVC. Taken together, these two parameters provide a more complete prediction of lateral stability for small UAVs with supersonic design configurations. Future development work on this project could benefit from a detailed lateral stability study, thorough engine intake design, and improvements to the launch rail used to accelerate the aircraft.
Non-detection of previously reported transits of HD 97658b with MOST photometry
Creators: name: Dragomir, Diana
name: Matthews, Jaymie M.
name: Howard, Andrew W.
name: Antoci, Victoria
name: Henry, Gregory W.
name: Guenther, David B.
name: Johnson, John A.
name: Kuschnig, Rainer
name: Marcy, Geoffrey W.
name: Moffat, Anthony F. J.
name: Rowe, Jason F.
name: Rucinski, Slavek M.
name: Sasselov, Dimitar
name: Weiss, Werner W.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The radial velocity-discovered exoplanet HD 97658b was recently announced to transit, with a derived planetary radius of 2.93 \pm 0.28 R_{Earth}. As a transiting super-Earth orbiting a bright star, this planet would make an attractive candidate for additional observations, including studies of its atmospheric properties. We present and analyze follow-up photometric observations of the HD 97658 system acquired with the MOST space telescope. Our results show no transit with the depth and ephemeris reported in the announcement paper. For the same ephemeris, we rule out transits for a planet with radius larger than 2.09 R_{Earth}, corresponding to the reported 3σlower limit. We also report new radial velocity measurements which continue to support the existence of an exoplanet with a period of 9.5 days, and obtain improved orbital parameters.
description: 16 pages, 4 figures; 1 Table; accepted for publication in ApJL, includes changes made in response to the referee report
O'ZBEKISTON RESPUBLIKASI XALQARO MUNOSABATLARINING DASTLABKI O'N YILLIK TARIXI VA MOHIYATI
Creators: name: G'abdullayev, Xaitboy
Publisher: name: Zenodo
Year: 2023

description: O'zbekiston Respublikasi mustaqillika erishganidan so'ng nafaqat qo'shni va qardosh xalqlar bilan,balki dunyoning eng yetakchi davlatlari bilan ham aktiv munosabatlarni yo'lga qo'ydi.Dunyoning eng ravnaq topgan davlatlari diyorimiz suvernitetini hech qanday istisnolarsiz tan oldi. Ushbu tezisda yurtimizning XX asrdagi (1991-2000) AQSH, Xitoy Xalq Respublikasi (XXR),  Hindiston va Korea  Respublikasi davlatlar bilan bo'lgan aloqalari va ularning mazmun-mohiyati yoritib beriladi.
Vietoris$\unicode{x2013}$Rips Complexes of Metric Spaces Near a Metric Graph
Creators: name: Majhi, Sushovan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics

description: For a sufficiently small scale $β>0$, the Vietoris$\unicode{x2013}$Rips complex $\mathcal{R}_β(S)$ of a metric space $S$ with a small Gromov$\unicode{x2013}$Hausdorff distance to a closed Riemannian manifold $M$ has been already known to recover $M$ up to homotopy type. While the qualitative result is remarkable and generalizes naturally to the recovery of spaces beyond Riemannian manifolds$\unicode{x2014}$such as geodesic metric spaces with a positive convexity radius$\unicode{x2014}$the generality comes at a cost. Although the scale parameter $β$ is known to depend only on the geometric properties of the geodesic space, how to quantitatively choose such a $β$ for a given geodesic space is still elusive. In this work, we focus on the topological recovery of a special type of geodesic space, called a metric graph. For an abstract metric graph $\mathcal{G}$ and a (sample) metric space $S$ with a small Gromov$\unicode{x2013}$Hausdorff distance to it, we provide a description of $β$ based on the convexity radius of $\mathcal{G}$ in order for $\mathcal{R}_β(S)$ to be homotopy equivalent to $\mathcal{G}$. Our investigation also extends to the study of the Vietoris$\unicode{x2013}$Rips complexes of a Euclidean subset $S\subset\mathbb{R}^d$ with a small Hausdorff distance to an embedded metric graph $\mathcal{G}\subset\mathbb{R}^d$. From the pairwise Euclidean distances of points of $S$, we introduce a family (parametrized by $\varepsilon$) of path-based Vietoris$\unicode{x2013}$Rips complexes $\mathcal{R}^\varepsilon_β(S)$ for a scale $β>0$. Based on the convexity radius and distortion of the embedding of $\mathcal{G}$, we show how to choose a suitable parameter $\varepsilon$ and a scale $β$ such that $\mathcal{R}^\varepsilon_β(S)$ is homotopy equivalent to $\mathcal{G}$.
Lateral Stability of Vehicle with Interlocking Spikes
Creators: name: Nannen, Volker
name: Bover, Damian
Publisher: name: arXiv
Year: 2022
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: The interlock drive system generates traction by penetrating narrow articulated spikes into the ground and by using the strength of the deeper soil layers to resist horizontal draft forces. The system promises good tractive performance in low gravity environments where tires generate little traction due to low vehicle weight. Possible applications include heavy-duty vehicles for civil engineering tasks like earthmoving or mining excavation. Safe vehicle operation in complex terrain geometry requires lateral vehicle stability to prevent vehicle rollover. Good lateral stability is a particular requirement for excavation and piling operations where the margins of safety define the terrain geometry that can be worked in, and it is a major constraint in operational planning. An earthmoving vehicle that can operate at a high roll angle reduces the need to maintain ramps in pits and on piles and can shorten and simplify the paths for individual maneuvers. Here we report on several field trials on the lateral stability of an earthmoving vehicle that uses the interlock drive systems. We find that the vehicle can work well at roll angles of up to 20°, but that it needs further improvement if work at roll angles of 30° or more is required.
An Epidemiological Study on Risk Factors for the Development of Serious Mental Illness In At-Risk Youth
Creators: name: Jalali, Sara
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Youth mental health
subject: Transition to serious mental illness
subject: Clinical staging
subject: Epidemiology
subject: Mental Health

description: Usually, mental illnesses begin in adolescence and early adulthood, and for many, persist over time. Consequently, mental illnesses lead to significant personal and societal burden. In response, there has been increasing effort in early intervention strategies that may help with delaying or stopping the progression of a mental illness to a more serious state. Aside from finding early intervention strategies best suited for young people, it is imperative to understand the psychosocial, biological and environmental factors that may lead to the development of a mental illness. Research on these early factors in youth mental illness development is limited. The aim of this study was to determine which clinical factors might be related to the development of a serious mental illness (SMI) in at-risk youth. A total of 162 participants aged 12-26 years and at various stages of risk for SMI were included in the study. Out of these participants, 31 developed a SMI. Comparisons were made on a range of baseline clinical and functional measures between two groups; those that made a transition to a SMI (n=31) and those that did not (n=131). A cox regression analysis was used to assess the relationship between measures and SMI development. Female sex, attenuated psychotic symptoms as assessed with the Scale of Psychosis-risk Symptoms (SOPS), and higher ratings on the K-10 Distress Scale were found to be significantly related to later transition to a SMI. Female participants were 2.77 times more likely to transition to SMI compared to the males. There was a 14% increased risk of transition with each one-point increase in the SOPS, and a 7% increase with a one-point increase in the K-10 scale. Results from this longitudinal study may help improve understanding of illness trajectory and aid with early detection in mental illnesses.
ELEKTRON TIJORAT PLATFORMALARINING EKOLOGIK TOZA QISHLOQ MAHSULOTLARI BOZORIGA TA'SIRI
Creators: name: Qodirov, Farrux
name: Turayeva, Sabrina
Publisher: name: Zenodo
Year: 2025

description: Zamonaviy texnologiyalar va internetning jadal rivojlanishi bilan elektron tijorat (e-commerce) platformalari har bir sohada, jumladan, qishloq xo'jaligi mahsulotlari bozori va ekologik toza mahsulotlar savdosida katta o'rin egalladi. Elektron tijorat orqali ekologik toza qishloq mahsulotlarini sotish, iste'molchilarga sog'lom va ekologik toza mahsulotlarni oson yetkazib berish imkoniyatini yaratadi. Ushbu maqolada elektron tijorat platformalarining ekologik toza qishloq mahsulotlari bozoriga ta’siri tahlil qilinadi.
Traction of Interlocking Spikes on a Granular Material
Creators: name: Nannen, Volker
name: Bover, Damian
Publisher: name: arXiv
Year: 2022
Subjects: subject: Robotics (cs.RO)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The interlock drive system generates traction by inserting narrow articulated spikes into the ground and by leveraging the soil's strength to resist horizontal draft forces. The system promises high tractive performance in low gravity environments where tires have little traction for lack of weight. At Earth and Space 2021 we reported the performance of such spikes on a silty clay loam, a cohesive soil. We found that in such soil, traction below a critical depth is provided by a zone of lateral soil failure. We also found that the articulation translates a horizontal draft force into a vertical penetration force strong enough to penetrate a narrow spike to a depth where the soil can sustain the draft force, in a self-regulating way. It is conceivable that a granular material like regolith or sand with little to no cohesive strength provides less vertical penetration resistance and less resistance to a horizontal draft force than a cohesive soil, which leads to the question of whether and how much tractive force an interlocking spike can generate on a granular material. Here we report on field trials that study different spike designs in dry and unsaturated moist sand. The results demonstrate that a loose granular material requires larger spikes than a cohesive soil, that these larger spikes penetrate dry and moist sand reliably, and that they promise good tractive efficiency. The trials indicate that on sand, a larger spike diameter can improve the pull/weight ratio without a loss of tractive performance.
Technologies of Surveillance: An Intersectional Analysis of Undocumented Caribbean Women Care Workers in the Labour Markets in Canada and the U.S.
Creators: name: Thomas, Carieta Oniefa
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Ethnic and Racial Studies
subject: Industrial and Labor Relations
subject: Women's Studies

description: Immigrant care workers play a considerable role in filling the gaps in care systems in the Global North. In this context, care work is increasingly stratified by gender, race, and immigration status, and racialized undocumented immigrant care workers occupy the lowest rung of the ladder in almost all cases. This study explores how government processes in the form of immigration regulation and surveillance affect the labour market participation and outcomes of undocumented immigrant women care workers from the Caribbean. The study focuses on the role pre-employment screening is playing in the management of undocumented Caribbean women care workers within the labour force in the U.S. and Canada. The study uses qualitative multi-level analysis to demonstrate the ways in which the local and relational experiences of the employers and undocumented care workers result from the matrix of domination embedded within the immigration and care work regimes. Interpretive policy analysis of [imm]ployment law at the macro level shows that governmentality practices sort immigrants into discrete categories for surveillance and control, resulting in marginalization and exploitation for those categorized as temporary, deportable, and undeserving. Analysis of 12 semi-structured interviews of care worker employers reveals that in addition to engaging in surveillance through preemployment screening of potential care workers, employers in the formal care market are also subjected to discipline and surveillance. Employers in the informal care market likewise engage in pre-employment screening, but their processes for hiring are more dependent on affective criteria and cultural matching. An analysis of 18 semi-structured interviews of undocumented care workers shows the ways the macro level immigration and employment laws, as well as the meso level employer practices, intervene in the lives of the undocumented care workers and engender their exploitation and marginalization through disciplining and techniques of the self. Using the extended case method, the study also finds three extensions of system avoidance theory based on the system avoidance practices and processes of the care workers. Beyond system avoidance practices, the study found that surveillance on the labour market disciplined the care workers into accepting exploitation.
title: Botanicals: An Interactive Pedagogical Webcomic
Creators: name: Bahl, Erin Kathleen
Publisher: name: The Digital Review
Year: 2021

description: To demonstrate a designerly approach to teaching through critical making and design, this project presents an interactive webcomic that simulates an interface for an online asynchronous course on professional writing. In particular, Bahl relies on the framing metaphor of the greenhouse, growing plants, and botanical diagrams to create a shared conceptual space between students and instructor. Through this project, Bahl approaches her pedagogical work as instructor in a way that reflects her commitment as a scholar to multimodal knowledge creation and to design as a way of knowing.
MAMLAKATIMIZDA INSON HUQUQLARI VA ERKINLIKLARINING HUQUQIY NAZARIYALARI
Creators: name: Akramova, Sevinch
Publisher: name: Zenodo
Year: 2023

description: Ushbu maqolada yangilanayotgan O'zbekistonda inson huquq va erkinliklariga doir katta o'zgarishlar, fuqarolik jamiyatini shakllantirishga qaratilgan islohotlar hamda inson huquqlari va manfaatlarini so'zsiz ta'minlash shuningdek, ushbu soha bo'yicha qabul qilinayotgan yuridik hujjatlar kabi masalalarga alohida to'xtalib o'tilgan.
Additional file 8: of Establishment of long-term serum-free culture for lacrimal gland stem cells aiming at lacrimal gland repair
Creators: name: Xiao, Sa
name: Zhang, Yan
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Figure S5. Engraftment of LGSC allotransplantation. A. The fluorescent images of NOD/ShiLtJ organs at 10 days post tail vein injection of ROSA-LGSCs. LG, lacrimal gland; SG, salivary gland. B, C. Immunofluorescent staining with anti-td-Tomato antibody of NOD/ShiLtJ LG tail vein injected with ROSA-LGSCs cultured for 7 days after 10 days. B. LG injected with ROSA-LGSCs (white arrow, green, exogenous cells). C. LG injected with vehicle; scale bar, 100 μm. D–F. IHC staining with anti-td-Tomato antibody of NOD/ShiLtJ LG transplanted with ROSA-LGSCs cultured for 7 days after 8 weeks. D. LG injected with vehicle. E. LG injected with ROSA-LGSCs. F. the magnified image of the black frame in E (red arrow, intra-lobular duct; red arrowhead, acini); scale bar, 100 μm (PDF 10480 kb)
ACME Stellar Spectra. I. Absolutely Calibrated, Mostly Empirical Flux Densities of 55 Cancri and its Transiting Planet 55 Cancri e
Creators: name: Crossfield, Ian J. M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The ACME Spectra project provides absolutely calibrated, mostly empirical spectra of exoplanet host stars for use in analysis of the stars and their planets. Spectra are obtained from ground-based telescopes and are tied directly to calibrated ground- and space-based photometry. The spectra remain only "mostly" empirical because of telluric absorption, but interpolation of stellar models over the gaps in wavelength coverage provides continuous stellar spectra. Among other uses, the spectra are suitable for precisely converting observed secondary eclipses (occultations) into absolute flux units with minimal recourse to models. In this letter I introduce ACME's methods and present a calibrated spectrum of the nearby, super-Earth hosting star 55 Cancri that spans the range from 0.81-5.05 micron. This spectrum is well-suited for interpreting near- and thermal-infrared eclipse observations. With this spectrum I show that the brightness temperature of the small, low-mass transiting planet 55 Cnc e is 1950 +260/-190 K at 4.5 micron (cooler than previously reported), which corresponds to a planetary flux of 0.44 +0.12/-0.08 mJy. This result suggests the planet has some combination of a nonzero albedo, a moderately efficient redistribution of absorbed stellar irradiation, and/or an optically thick atmosphere, but more precise eclipse measurements are required to distinguish between these scenarii.
description: Accepted to A&A. 6 pages, 1 figure, 1 electronic table. See http://irtfweb.ifa.hawaii.edu/~spex/IRTF_Spectral_Library/ for an alternative spectrum
The evolution of swimming capacity among migratory and non-migratory populations of the threespine stickleback (Gasterosteus aculeatus)
Creators: name: Dalziel, Anne Cecilia
Publisher: name: University of British Columbia
Year: 2012

description: Understanding how complex traits evolve is critical for understanding how animals meet environmental challenges. In my dissertation I studied the mechanisms by which prolonged swimming performance (Ucrit), a complex whole-animal performance trait, has evolved among ancestral anadromous-marine and derived non-migratory stream-resident ecotypes of threespine stickleback (Gasterosteus aculeatus). I showed that stream-resident populations from Bonsall and West Creeks have evolved a decreased Ucrit, but via different genetic mechanisms, and that three additional wild stream-resident populations also had low Ucrits. Collectively, these data are consistent with a role for natural selection in the evolution of a reduced capacity for prolonged swimming after freshwater colonization. I next determined which candidate morphological, physiological, and biochemical traits evolved in conjunction with these decreases in Ucrit capacity in Bonsall and West Creek stream- resident populations. I found that a number of traits predicted to influence Ucrit in fishes evolved as predicted in both stream-resident populations. To further assess the associations between these candidate traits and Ucrit, I compared the genetic architecture of Ucrit with the genetic architecture of candidate traits by comparing F1 hybrids to pure F1 crosses. I found that a number of candidate traits had a similar genetic architecture as Ucrit, but that many of these traits were population-specific. These data suggest that non-parallel genetic, morphological and physiological mechanisms may contribute to the evolution of similar performance capacities. To test the associations between candidate traits and Ucrit, I correlated traits with Ucrit in Bonsall Creek F2 hybrids. In F2 hybrids the complete linkage of all divergent traits in F1 crosses is partially broken apart. I found that only four candidate traits (ventricle mass, adductor mass, and adductor and abductor citrate synthase activities) significantly regressed against Ucrit in F2 hybrids, accounting for 17.9% of variation in Ucrit. These data suggest that, when dissociated from other traits, many candidate traits do not have a strong effect on Ucrit, additional unmeasured traits are likely to influence Ucrit, and that many traits are necessary to reach a high Ucrit. This dissertation provides a clear empirical example of the patterns of evolution in a complex trait and its underlying mechanisms.
Randomization-Based Methods For Treatment Comparisons For Dichotomous Outcomes For Multiple Anatomical Regions
Creators: name: Yu, Jing
name: Koch, Gary
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Some clinical trials in ophthalmology or dermatology randomize patients into two or more treatment groups, and observations are made for one or more anatomical regions (or sites) for each patient. In this case, patients are primary sampling units, and their responses for multiple anatomical sites are usually correlated. Useful randomization-based extensions of the Cochran-Mantel-Haenszel (CMH) method are discussed here for such studies; and aspects of their application are illustrated with two examples. The first example is a randomized ophthalmology clinical trial with the number of treated eyes as strata and a dichotomous response criterion. The second example is a randomized dermatology clinical trial with three strata for the number of treated anatomical regions among the face, scalp, or chest, one covariable (as disease severity at baseline), and a dichotomous outcome. For these examples, the results are interpretable through the proportions of treated sites with favorable outcome for each treatment and their difference between treatments.
Near-Field Channel Estimation in Mixed LoS/NLoS Environments for Extremely Large-Scale MIMO Systems
Creators: name: Lu, Yu
name: Dai, Linglong
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Theory (cs.IT)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Accurate channel model and channel estimation are essential to empower extremely large-scale MIMO (XL-MIMO) in 6G networks with ultra-high spectral efficiency. With the sharp increase in the antenna array aperture of the XL-MIMO scenario, the electromagnetic propagation field will change from far-field to near-field. Unfortunately, due to the near-field effect, most of the existing XL-MIMO channel models fail to describe mixed line-of-sight (LoS) and non-line-of-sight (NLoS) path components simultaneously. In this paper, a mixed LoS/NLoS near-field XL-MIMO channel model is proposed to match the practical near-field XL-MIMO scenario, where the LoS path component is modeled by the geometric free space propagation assumption while NLoS path components are modeled by the near-field array response vectors. Then, to define the range of near-field for XL-MIMO, the MIMO Rayleigh distance (MIMO-RD) and MIMO advanced RD (MIMO-ARD) is derived. Next, a two stage channel estimation algorithm is proposed, where the LoS path component and NLoS path components are estimated separately. Moreover, the Cramer-Rao lower bound (CRLB) of the proposed algorithm is derived in this paper. Numerical simulation results demonstrate that, the proposed two stage scheme is able to outperform the existing methods in both the theoretical channel model and the QuaDRiGa channel emulation platform.
description: Accepted by IEEE TCOM. This paper investigates the channel estimation of the near-field XL-MIMO scenario. We propose the mixed LoS/NLoS near-field XL-MIMO channel model and the corresponding channel estimation scheme. In addition, the range of the near-field region of XL-MIMO is derived. Simulation codes will be provided at: http://oa.ee.tsinghua.edu.cn/dailinglong/publications/publications.html
O'ZBEKISTONNING JAHON SAVDO TASHKILOTIGA A'ZOLIK MAJBURIYATLARI VA MANFAATLARI
Creators: name: Norbekov, Fayzullo
Publisher: name: Zenodo
Year: 2023

description: Bugungi iqdisodiy va siyosiy munosabatlar rivojlanayotgan va ziddiyatlar keskinlashayotgan bir davrda xalqaro subyektlarning o'zaro tashqi munosabatlari ularning siyosatida muhim ahamiyatga ega hisoblanadi. Bundan kelib chiqadiki, xalqaro normalar, xalqaro shartnoma va tashkilotlar tashqi siyosatda muhim ahamiyatga ega. Uzoq muddatdan beri xalqaro iqdisodiy munosabatlarni tartibga solib kelayotgan, mamlakatlarning eksport, import salohiyatini oshirishga sharoit yaratib berayotgan va davlatlarning moliyaviy barqarorligini oshirishga ko'maklashayotgan shunday xalqaro tashkilotlardan biri bu Jahon Savdo Tashkilotidir. JST jahon savdosi qoidalarini ishlab chiqish yo'li bilan davlatlar savdo siyosatiga taʼsir ko'rsatish, savdo munosabatlarini erkinlashtiradigan va qat'iy tartib-qoidaga soladigan muzokaralar uchun yig'ilishlar oʻtkazish, davlatlararo savdoda yuzaga keladigan nizolarni hal qilish va boshqa vazifalarni bajaradi. Hozirda O'zbekiston bu tashkilotga a'zo davlatlar qatoriga kirmaydi, ammo davlatimiz rahbarining JST ga mamlakatimizning a'zo bo'lishi yolidagi harakatlari e'tiborga loyiq. Yaqin yillarda davlatimiz tashkilotga a'zo davlatlarning biriga aylanadi va bu mamlakatimizning iqdisodiy imkoniyatlarini kengaytirish uchun yangi eshiklarni ochishi shubhasiz.
Stability of Spinmotive Force in Perpendicularly Magnetized Nanowires under High Magnetic Fields
Creators: name: Yamane, Yuta
name: Ieda, Jun'ichi
name: Maekawa, Sadamichi
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Spinmotive force induced by domain wall motion in perpendicularly magnetized nanowires is numerically demonstrated. We show that using nanowires with large magnetic anisotropy can lead to a high stability of spinmotive force under strong magnetic fields. We observe spinmotive force in the order of tens of microvolt in a multilayered Co/Ni nanowire and in the order of several hundred microvolt in a FePt nanowire; the latter is two orders of magnitude greater than that in permalloy nanowires reported previously. The narrow structure and low mobility of a domain wall under magnetic fields in perpendicularly magnetized nanowires permits downsizing of spinmotive force devices.
description: submitted to Applied Physics Letters
Automated Algorithm Selection for Radar Network Configuration
Creators: name: Renau, Quentin
name: Dreo, Johann
name: Peres, Alain
name: Semet, Yann
name: Doerr, Carola
name: Doerr, Benjamin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The configuration of radar networks is a complex problem that is often performed manually by experts with the help of a simulator. Different numbers and types of radars as well as different locations that the radars shall cover give rise to different instances of the radar configuration problem. The exact modeling of these instances is complex, as the quality of the configurations depends on a large number of parameters, on internal radar processing, and on the terrains on which the radars need to be placed. Classic optimization algorithms can therefore not be applied to this problem, and we rely on "trial-and-error" black-box approaches. In this paper, we study the performances of 13 black-box optimization algorithms on 153 radar network configuration problem instances. The algorithms perform considerably better than human experts. Their ranking, however, depends on the budget of configurations that can be evaluated and on the elevation profile of the location. We therefore also investigate automated algorithm selection approaches. Our results demonstrate that a pipeline that extracts instance features from the elevation of the terrain performs on par with the classical, far more expensive approach that extracts features from the objective function.
description: Author-generated version of a paper in the proceedings of The Genetic and Evolutionary Computation Conference 2022 (GECCO 2022)
Data Subset-Based Methods of Inference for Spatial Individual Level Epidemic Models
Creators: name: Nyein, Thet Htet Chan
Publisher: name: Science
Year: 2023
Subjects: subject: Bayesian inference
subject: Individual leve model
subject: Statistics
subject: FOS: Mathematics

description: Mathematical models are essential to understand infectious disease dynamics, enabling to control the spread of those diseases and preparing for public health measures. Since time and space are important factors affecting the transmission of infectious diseases, spatial individual-level models (ILM) with both temporal and spatial information are developed. Typically, Markov Chain Monte Carlo (MCMC) methods are utilized for the inference of ILM. Nonetheless, this approach can be computationally intensive for complex or large models, resulting in repeated likelihood calculations. This thesis explores various spatial and temporal subset methods to conduct statistical inference for spatial epidemic models, aiming to provide appropriate parameter estimates with minimum computational resources. In this thesis, we utilize the spatial ILM with the Euclidean distance between susceptible individuals and infectious individuals as a kernel function.