cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Vertical movements of Atlantic cod (Gadus morhua) in the Baltic and the North Sea
Creators: name: Neuenfeldt, Stefan
name: Payne, Mark
name: Righton, David
name: Der Kooij, Jeroen Vand
Publisher: name: ASC 2009 - Theme session J
Year: 2024
Subjects: Fisheries and aquaculture
Technologies and data

description: No abstracts are to be cited without prior reference to the author.Vertical movements of Atlantic cod (Gadus morhua) in the Baltic and the North Sea.
title: Pregnancy and Childbirth in Late Medieval English Vernacular Culture
Creators: name: Collins, Claire
Publisher: name: University of Reading
Year: 2024

description: Using evidence from a wide range of Middle English texts, this thesis aims to present an improved understanding of pregnancy and childbirth in fourteenth- and fifteenth-century England. This interdisciplinary approach makes it possible to present new insights and to go beyond questions of medical concepts and practices. The thesis also argues that Middle English texts are more likely than Latin sources to represent real practice, as those who translated and adapted these texts from Latin often omitted and added material from earlier works in line with contemporary knowledge. Additionally, these texts offer insight into information circulated to a wider audience, by providing access to those who could not read Latin. The thesis begins with an analysis of a selection of Middle English medical treatises to establish the medical treatments a pregnant or parturient woman might expect to receive, including: diagnosis of pregnancy or pregnancy loss; advice on keeping well during pregnancy; and dealing with complications during childbirth. The following chapters examine carefully selected herbals, lapidaries, pastoral literature, chronicles, and romances to reveal what these sources can add to our understanding of pregnancy and childbirth in late medieval England. The final chapter examines late medieval private letter collections. These letters, written by women as well as men, provide a unique insight into the actual, lived experience of pregnancy and childbirth in this period. Through comparison of this unique range of sources, the study is able to provide contextualisation and corroboration of evidence found across Middle English vernacular culture. Through this approach, a portrait of the contemporary attitudes, practices, and experiences surrounding pregnancy and childbirth is drawn. Notably, it is shown that pregnancy and childbirth had emotional, spiritual, social, and political implications, and were not considered a solely medical concern. Finally, the merits of this approach having been established, a number of avenues for further research are offered.
Stochastic Heating by ECR as a Novel Means of Background Reduction in the KATRIN Spectrometers
Creators: name: Mertens, S.
name: Beglarian, A.
name: Bornschein, L.
name: Drexlin, G.
name: Fränkle, F. M.
name: Furse, D.
name: Glück, F.
name: Görhardt, S.
name: Krömer, O.
name: Leiber, B.
name: Schlösser, K.
name: Thümmler, T.
name: Wandkowsky, N.
name: Wüstling, S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The primary objective of the KATRIN experiment is to probe the absolute neutrino mass scale with a sensitivity of 200 meV (90% C.L.) by precision spectroscopy of tritium beta-decay. To achieve this, a low background of the order of 10^(-2) cps in the region of the tritium beta-decay endpoint is required. Measurements with an electrostatic retarding spectrometer have revealed that electrons, arising from nuclear decays in the volume of the spectrometer, are stored over long time periods and thereby act as a major source of background exceeding this limit. In this paper we present a novel active background reduction method based on stochastic heating of stored electrons by the well-known process of electron cyclotron resonance (ECR). A successful proof-of-principle of the ECR technique was demonstrated in test measurements at the KATRIN pre-spectrometer, yielding a large reduction of the background rate. In addition, we have carried out extensive Monte Carlo simulations to reveal the potential of the ECR technique to remove all trapped electrons within negligible loss of measurement time in the main spectrometer. This would allow the KATRIN experiment attaining its full physics potential.
Conformal Standard Model
Creators: name: Fabbri, Luca
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In recent papers we have constructed the conformal theory of metric-torsional gravitation, and in this paper we shall include the gauge fields to study the conformal U(1) X SU(2) Standard Model; we will show that the metric-torsional degrees of freedom give rise to a potential of conformal-gauge dynamical symmetry breaking: consequences are discussed.
description: 9 pages
Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology
Creators: name: Nuriel, Tal
name: Angulo, Sergio L.
name: Khan, Usman
name: Ashok, Archana
name: Chen, Qiuying
name: Figueroa, Helen Y.
name: Emrani, Sheina
name: Liu, Li
name: Herman, Mathieu
name: Barrett, Geoffrey
name: Savage, Valerie
name: Cepeda-Prado, Efrain
name: Fung, Christine
name: Goldberg, Eliana
name: Gross, Steven S.
name: Hussaini, Syed Abid
name: Moreno, Herman
name: Small, Scott A.
Publisher: name: Columbia University
Year: 2017
Subjects: Alzheimer's disease
Hippocampus (Brain)
Metabolism

description: The ε4 allele of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer’s disease (AD). However, the reason APOE4 is associated with increased AD risk remains a source of debate. Neuronal hyperactivity is an early phenotype in both AD mouse models and in human AD, which may play a direct role in the pathogenesis of the disease. Here, we have identified an APOE4-associated hyperactivity phenotype in the brains of aged APOE mice using four complimentary techniques—fMRI, in vitro electrophysiology, in vivo electrophysiology, and metabolomics—with the most prominent hyperactivity occurring in the entorhinal cortex. Further analysis revealed that this neuronal hyperactivity is driven by decreased background inhibition caused by reduced responsiveness of excitatory neurons to GABAergic inhibitory inputs. Given the observations of neuronal hyperactivity in prodromal AD, we propose that this APOE4-driven hyperactivity may be a causative factor driving increased risk of AD among APOE4 carriers.
Bradypus variegatus Schinz 1825
Creators: name: Torres-Porras, Jeronimo
name: Cobos, Marlon E
name: Seoane, José Manuel
name: Aguirre, Nikolay
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Pilosa
Bradypodidae
Bradypus
Bradypus variegatus

description: Bradypus variegatus Schinz, 1825: Figure 10 Bradypus variegatus Schinz 1825 — Tirira 2007, Moraes-Barros et al. 2014. Material examined: Table 1. Long, dense, thick and wavy pelage (except on the face), inverted from the belly to the back, the back is grayish, yellowish gray or pale grayish brown, marbled, and with prominent whitish stains; small and round head; face whitish to grayish brown; ears not visible covered by pelage; dark lips that simulate a slight smile; limbs very long and hairy, the former somewhat more than the hind limbs; each ending in three long, curved claws, in the form of a hook and creamy yellowish color; tail short thick and truncated, covered by abundant pelage (Tirira 2007).
description: Published as part of Torres-Porras, Jeronimo, Cobos, Marlon E, Seoane, José Manuel & Aguirre, Nikolay, 2017, Large and medium-sized mammals of Buenaventura Reserve, southwestern Ecuador, pp. 35-45 in Check List 13 (4) on page 41, DOI: 10.15560/13.4.35
description: {"references": ["Schinz HR (1825) Das Thierreich eingetheilt nach dem Bau der Thiere als Grundlage ihrer Naturgeschiechte und der vergleichenden Anatomie von dem Herrn Ritter von Cuvier. Volume 4. Cotta'schen Buchhandlung, Stuttgart / Tubingen, 792 pp.", "Tirira DS (2007) Guia de Campo de los Mamiferos del Ecuador. Publicacion especial sobre los mamiferos del Ecuador 6. Ediciones Murcielago Blanco, Quito, 576 pp.", "Moraes-Barros N, Chiarello A, Plese T (2014) Bradypus variegatus. The IUCN Red List of Threatened Species 2014: e. T 3038 A 47437046. https: // doi. org / 10.2305 / iucn. uk. 2014 - 1. rlts. t 3038 a 47437046. en"]}
The necessity of entanglement and the equivalency of Bell's theorem with the second law of thermodynamics
Creators: name: Durham, Ian T.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We demonstrate that both Wigner's form of Bell's inequalities as well as a form of the second law of thermodynamics, as manifest in Carathéodory's principle, can be derived from the same simple experimental and statistical mechanical assumptions combined with the trivial behavior of integers. This suggests that Bell's theorem is merely a well-disguised statement of the second law. It also suggests that entanglement is necessary for quantum theory to be in full accord with the second law and thus builds on the results of Wiesniak, Vedral, and Brukner \cite{Marcin-Wiesniak:2008fv} who showed it was necessary for consistency with the third law.
description: Greatly simplified the derivation of the entropic inequality in the third section and added acknowledgements. Note that this is not the version that appears in the FPP-6 proceedings. When possible, please cite this version. 5 pages, 1 table, 1 figure
HyBryte™ use in early-stage cutaneous T-cell lymphoma
Creators: name: Haulenbeek, Andrea
name: Wong, Henry K.
name: Rook, Alain H.
name: Desimone, Jennifer
name: Kim, Ellen J.
name: Schaber, Christopher J.
name: Rumage, Adam T.
name: Mangold, Aaron R.
name: Pullion, Christopher
name: Poligone, Brian
name: Donini, Oreola
name: Alexander-Savino, Carolina V.
name: Straube, Richard
Publisher: name: Frontiers Media
Year: 2023

description: Cutaneous T-cell lymphoma (CTCL) is a rare type of non-Hodgkin lymphoma of the skin, where at later stages skin-homing malignant T-cells affect lymph nodes, blood, and visceral organs. Even though early CTCL does not affect survival, it can progress to more advanced stages of disease and have a significant effect on the quality of life of patients. Although expectant management is a treatment consideration in early disease stages, most patients cycle through different skin-directed therapies throughout their lifetime. It can become a challenge to manage the serious and accumulating risk of side effects of these therapies, including various skin cancers and skin damage. Adverse effects from topical therapies limit their long-term utility. Thus, there is an unmet need for well-characterized therapies that have a rapid onset of action and minimal long-term/cumulative side effect profile. Most recently, the results of a Phase 3 study of topical HyBryte™ as a potential treatment for CTCL demonstrated its efficacy and safety profile. This article summarizes what is known about HyBryte™, focuses on its mechanism of action, and highlights its effectiveness, safety, and tolerability in the context of other current FDA-approved topical therapies for CTCL.
Dasyprocta punctata Gray 1842
Creators: name: Torres-Porras, Jeronimo
name: Cobos, Marlon E
name: Seoane, José Manuel
name: Aguirre, Nikolay
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Dasyproctidae
Dasyprocta
Dasyprocta punctata

description: Dasyprocta punctata Gray, 1842: Figure 8 Dasyprocta punctata Gray 1842 — Tirira 2007, Emmons 2016a. Material examined: Table 1. Medium-sized; the back is reddish brown to uniform yellowish brown; the chin and inguinal region are pale orange, while the rest of the belly is pale yellow; back slightly curved; short, hairy and inconspicuous tail (Tirira 2007).
description: Published as part of Torres-Porras, Jeronimo, Cobos, Marlon E, Seoane, José Manuel & Aguirre, Nikolay, 2017, Large and medium-sized mammals of Buenaventura Reserve, southwestern Ecuador, pp. 35-45 in Check List 13 (4) on page 42, DOI: 10.15560/13.4.35
description: {"references": ["Gray JE (1842) Descriptions of some new genera and fifty unrecorded species of Mammalia. Journal of Natural History 10: 255 - 267.", "Tirira DS (2007) Guia de Campo de los Mamiferos del Ecuador. Publicacion especial sobre los mamiferos del Ecuador 6. Ediciones Murcielago Blanco, Quito, 576 pp.", "Emmons L (2016 a) Dasyprocta punctata. The IUCN Red List of Threatened Species 2016: e. T 89497686 A 78319610. https: // doi. org / 10.2305 / iucn. uk. 2016 - 2. rlts. t 89497686 a 78319610. en"]}
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
Creators: name: Saal, Lao H.
name: Gruvberger-Saal, Sofia K.
name: Persson, Camilla
name: Lövgren, Kristina
name: Jumppanen, Mervi
name: Staaf, Johan
name: Jönsson, Göran
name: Pires, Maira M.
name: Maurer, Mathew
name: Holm, Karolina
name: Koujack, Susan
name: Subramaniyam, Shivakumar
name: Vallon-Christersson, Johan
name: Olsson, Håkan
name: Su, Tao
name: Memeo, Lorenzo
name: Ludwig, Thomas
name: Ethier, Stephen P.
name: Krogh, Morton
name: Szabolcs, Matthias
name: Vundavalli, Murty V.
name: Isola, Jorma
name: Hibshoosh, Hanina
name: Parsons, Ramon E.
name: Borg, Åke
Publisher: name: Columbia University
Year: 2008
Subjects: Breast--Cancer--Genetic aspects
BRCA genes
Oncogenes
Genomics
Cytogenetics

description: Basal-like breast cancer (BBC) is a subtype of breast cancer with poor prognosis. Inherited mutations of BRCA1, a cancer susceptibility gene involved in double-strand DNA break (DSB) repair, lead to breast cancers that are nearly always of the BBC subtype; however, the precise molecular lesions and oncogenic consequences of BRCA1 dysfunction are poorly understood. Here we show that heterozygous inactivation of the tumor suppressor gene Pten leads to the formation of basal-like mammary tumors in mice, and that loss of PTEN expression is significantly associated with the BBC subtype in human sporadic and BRCA1-associated hereditary breast cancers. In addition, we identify frequent gross PTEN mutations, involving intragenic chromosome breaks, inversions, deletions and micro copy number aberrations, specifically in BRCA1-deficient tumors. These data provide an example of a specific and recurrent oncogenic consequence of BRCA1-dependent dysfunction in DNA repair and provide insight into the pathogenesis of BBC with therapeutic implications. These findings also argue that obtaining an accurate census of genes mutated in cancer will require a systematic examination for gross gene rearrangements, particularly in tumors with deficient DSB repair.
Comment on `Electromagnetic force on a moving dipole'
Creators: name: Hnizdo, V.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: Using the Lagrangian formalism, the electromagnetic force on a moving dipole derived by Kholmetskii, Missevitch and Yarman (2011, Eur. J. Phys. 32, 873) is found to be missing some important terms.
description: The version as accepted by Eur. J. Phys.; 4 pages
title: Satellite monitoring of SST for forecasting of the North-east arctic cod year class strength
Creators: name: Borisov, V.M.
name: Vanyushin, G.P.
name: B.N.Kotenev
name: M.Yu.Kruzhalov
name: А.А.Troshkov
name: Bulatova, T.V.
Publisher: name: ASC 2009 - Theme session K
Year: 2024
Subjects: Fisheries and aquaculture
Ecosystem observation, processes and dynamics

description: No abstracts are to be cited without prior reference to the author.Continuous long-term database on the sea surface temperature (SST) comprising results of regional differentiated satellite monitoring is used to resolve several applied problems. Authors have analyzed indirect influence of SST (the NOAA satellites data) on strength of the North-east Arctic cod year class strength (abundance at age 3+). Four areas have been selected in the area of the cod distribution to analyze SST in particular months: spawning grounds off the Lofoten islands to analyze SST (March –April) and three zones of the larval drift and the pelagic young fish distribution: the West-Spitsbergen waters and the Bear- Spitsbergen (Nordcap) area (MayOctober), and Murman-Novaya Zemlya area to analyze SST in June-October. Mean monthly SST and anomalous values are computed for the selected areas on the basis of the weekly SST maps for the period of 1998-2008. These maps were plotted with the satellite SST data, as well as information of vessel, buoy, and coastal stations. All data on each the area were classified by seasons and years
Diffuse large B-cell lymphoma with TEL/ETV6 translocation
Creators: name: Sevilla, Deborah W.
name: Nandula, Subhadra
name: Colovai, Adriana I.
name: Alexander, Suzy
name: Vundavalli, Murty V.
name: Alobeid, Bachir
name: Bhagat, Govind
Publisher: name: Columbia University
Year: 2009
Subjects: Cytogenetics
Lymphomas
Translocation (Genetics)
Karyotypes

description: Cytogenetic abnormalities of chromosome 12p involving the TEL/ETV6 gene are observed in a variety of hematopoietic neoplasms including acute leukemias, myelodysplastic syndromes, and myeloproliferative disorders. Karyotypic aberrations, including rearrangements, deletions, and amplifications of chromosome 12p, have been documented in B-cell non-Hodgkin lymphoma; however, rearrangements targeting TEL have rarely been reported. Here we describe a diffuse large B- cell lymphoma that had a complex karyotype including t(9;12)(q22;p13), which was confirmed by fluorescence in situ hybridization to represent rearrangement of TEL. Additional cytogenetic abnormalities included t(3;14)(q27;q32) involving the variant, alternative breakpoint region of the BCL6 gene and del(6)(q13q23), resulting in the loss of 1 allele of BLIMP1. This case reiterates the importance of correlating morphologic and phenotypic findings with the results of cytogenetic analysis to avoid errors in diagnosing hematologic neoplasms and highlights the rare association of B-cell non- Hodgkin lymphoma with aberrations of TEL.
Sine-Gordon multi-soliton form factors in finite volume
Creators: name: Feher, G. Z.
name: Palmai, T.
name: Takacs, G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Multi-soliton form factors in sine-Gordon theory from the bootstrap are compared to finite volume matrix elements computed using the truncated conformal space approach. We find convincing agreement, and resolve most of the issues raised in a previous work.
description: 24 pages, LaTeX2e file, 8 eps figures. v2: notations improved, some explanatory text and references added
Two Mazandarani Texts from the Nineteenth Century
Creators: name: Borjian, Habib
Publisher: name: Columbia University
Year: 2008
Subjects: Māzandarānī language
Iranian languages
Manuscripts
History
Historical linguistics

description: This article transcribes, translates, and compiles a glossary for two Mazandarani texts written in 1889 in the town of Barforush and published as facsimiles by Jacques de Morgan. The language of the texts, Mazandarani or New Tabari, is fundamentally similar to that spoken today by more than three million people in the Persian province of Mazandaran, located south of the Caspian Sea. However, there are several extinct words and grammatical traits in the texts, which could be identified only by drawing on other surviving Mazandarani documents of the same period. The texts are meant to contribute to the study of the largely understudied language of Mazandaran, a northwestern Iranian language. They may also serve as historical documents, for they relate certain events in such details not found in other sources. Ample historical remarks follow the texts.
A study of two wideband CMOS LC-VCO structures
Creators: name: Yu, Ge
Publisher: name: University of British Columbia
Year: 2012

description: Phase-locked loops (PLLs) are widely used in telecommunication, radio, and computer applications. This thesis focuses on the study of wide-band PLLs, as they are a critical building block of many wireless and wireline systems. In particular, wide tuning range, low phase noise, and low power are desirable attributes for multi-standard and multi-band communication systems. One of the most critical components in a PLL is the voltage-controlled oscillator (VCO). In this work, two techniques for implementing a wide-tuning-range LC-VCO are presented. As a proof of concept, the techniques are used to design and layout two 13-GHz LC-VCOs, which are fabricated in a 90-nm CMOS technology and successfully tested. One design (Design A) uses two VCO cores and has an extra source-follower buffer while the other (Design B) uses one VCO core with a bank of switched capacitors. The 90-nm CMOS prototypes operate from a supply of 1.2 V. The Design A prototype has a 28.20% tuning range and a phase noise of ‒90.98 dBc/Hz at 1 MHz offset from the carrier, while the Design B prototype has a 24.42% tuning range and a phase noise of ‒94.20 dBc/Hz at 1 MHz offset. This measured performance is comparable with state-of-the-art wide-tuning-range VCOs. The total chip size, excluding pads, is 0.335 × 0.750 mm² and 0.316 × 0.425 mm² for Designs A and B, respectively. It was found that the addition of the source-follower buffer allows the VCO to function at a higher frequency, while the presence of the switched capacitor tends to deteriorate phase noise.
Tomographic weak lensing shear spectra from large N-body and hydrodynamical simulations
Creators: name: Casarini, Luciano
name: Bonometto, Silvio A.
name: Borgani, Stefano
name: Dolag, Klaus
name: Murante, Giuseppe
name: Mezzetti, Marino
name: Tornatore, Luca
name: La Vacca, Giuseppe
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Forthcoming experiments will enable us to determine tomographic shear spectra at a high precision level. Most predictions about them have until now been biased on algorithms yielding the expected linear and non-linear spectrum of density fluctuations. Even when simulations have been used, so-called Halofit (Smith et al 2003) predictions on fairly large scales have been needed. We wish to go beyond this limitation. We perform N-body and hydrodynamical simulations within a sufficiently large cosmological volume to allow a direct connection between simulations and linear spectra. While covering large length-scales, the simulation resolution is good enough to allow us to explore the high-l harmonics of the cosmic shear (up to l ~ 50000), well into the domain where baryon physics becomes important. We then compare shear spectra in the absence and in presence of various kinds of baryon physics, such as radiative cooling, star formation, and supernova feedback in the form of galactic winds. We distinguish several typical properties of matter fluctuation spectra in the different simulations and test their impact on shear spectra. We compare our outputs with those obtainable using approximate expressions for non--linear spectra, and identify substantial discrepancies even between our results and those of purely N-body results. Our simulations and the treatment of their outputs however enable us, for the first time, to obtain shear results taht are fully independent of any approximate expression, also in the high-l range, where we need to incorporate a non-linear power spectrum of density perturbations, and the effects of baryon physics. This will allow us to fully exploit the cosmological information contained in future high--sensitivity cosmic shear surveys, exploring the physics of cosmic shears via weak lensing measurements.
description: 13 pages, 19 figures, A&A in press
IgE and IgG4 epitopes of the peanut allergens shift following oral immunotherapy
Creators: name: Rivers, Adam R.
name: Kronfel, Christina M.
name: Rambo, Ian M.
name: Maleki, Soheila J.
name: Hurlburt, Barry K.
name: Kulis, Michael D.
name: Nesbit, Jacqueline B.
name: Tilles, Stephen A.
name: Ryan, Robert
name: Simon, Reyna J.
name: Cheng, Hsiaopo
name: McBride, Jane K.
name: Swientoniewski, Lauren T.
Publisher: name: Frontiers Media
Year: 2023

description: Background Oral immunotherapy (OIT) with peanut (Arachis hypogaea) allergen powder-dnfp (PTAH; Aimmune Therapeutics) is an FDA-approved treatment to desensitize peanut allergic participants. Objective Here we assessed shifts in IgE and IgG4 binding to peanut allergens and their epitopes recognized by United States (US) peanut allergic participants (n = 20) enrolled in phase 3 PTAH OIT clinical trials. Methods Pre- and post- trial participant sera were collected approximately 12 months apart and tested for IgE binding to intact peanut proteins via ImmunoCAP ISAC immunoassays. IgE and IgG4 linear epitopes were identified based on binding to synthetic overlapping 15-mer linear peptides of 10 peanut allergens (Ara h 1-11) synthesized on microarray slides. Results Statistically significant decreases in IgE binding were identified for intact Ara h 2, 3, and 6, and known and newly identified IgE epitopes were shown to exhibit shifts towards IgG4 binding post-OIT, with most linear peptides having increased IgG4 binding after treatment with PTAH. While PTAH does not seem to alter the actual peptide binding patterns significantly after one year of treatment, the IgE and IgG4 binding ratios and intensity are altered. Conclusion At a population level, the linear IgE and IgG4 epitopes of 10 peanut allergens overlap and that increase in IgG4 with OIT results in displacement of IgE binding to both conformational and linear epitopes. Furthermore, it appears as though the increase in IgG4 is more important to achieve desensitization at the 12-month timepoint than the decrease in IgE. This type of knowledge can be useful in the identification of IgE and IgG4-binding allergen and peptide biomarkers that may indicate desensitization or sustained unresponsiveness of allergic individuals to peanut.
Effects of stratification in spherical shell convection
Creators: name: Käpylä, P. J.
name: Mantere, M. J.
name: Brandenburg, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report on simulations of mildly turbulent convection in spherical wedge geometry with varying density stratification. We vary the density contrast within the convection zone by a factor of 20 and study the influence of rotation on the solutions. We demonstrate that the size of convective cells decreases and the anisotropy of turbulence increases as the stratification is increased. Differential rotation is found to change from anti-solar (slow equator) to solar-like (fast equator) at roughly the same Coriolis number for all stratifications. The largest stratification runs, however, are sensitive to changes of the Reynolds number. Evidence for a near-surface shear layer is found in runs with strong stratification and large Reynolds numbers.
description: 7 pages, 9 figures, published version
FLEXIGRID ́s Visual Materials and Identity Set
Creators: name: Nogues, Jorge Val
Publisher: name: Zenodo
Year: 2021

description: The main outcome of this deliverable, related to Task 9.2 will be the materials to be developed such as leaflets, posters, roll-ups, etc. It will also include the project identity set. The materials will be developed during the whole duration of the project and updated at month 18, 36 and 48.
Surveillance Detection in High Bandwidth Environments
Creators: name: Robertson, Seth
name: Siegel, Eric V.
name: Miller, Matt
name: Stolfo, Salvatore
Publisher: name: Columbia University
Year: 2003
Subjects: Computer science

description: In this paper, we describe System Detection's surveillance detection techniques for enclave environments (ESD) and peering center environments (PSD) and evaluate each technique over data gathered from two different network environments. ESD is evaluated over 74 hours of tcpdump packet traces (344 million packets) from a large enclave; PSD is evaluated over 5 hours of tcpdump packet traces (110 million packets) gathered from a peering center. Both surveillance detection modules were executed over the audit data offline to generate surveillance detection alerts, though the systems can be run in real-time as well. Our results show that both ESD and PSD accurately discover great quantities of surveillance activities (including long-lived and distributed scans) and can be tuned to reduce the volume of alerts. Furthermore, existing IDS technology may be blind to many activities discovered by ESD and PSD.
title: Fish and Physics: Assessment of the power of Ocean Observing System data streams to explain habitat specific distributions of resource species in the coastal ocean
Creators: name: Manderson, John P.
name: Kohut, Josh
name: Palamara, Laura
name: Phelan, Beth
Publisher: name: ASC 2009 - Theme session K
Year: 2024
Subjects: Fisheries and aquaculture

description: No abstracts are to be cited without prior reference to the author.Because seascapes are viscous aqueous environments with a high heat capacity and solute concentrations similar to intracellular milieus, interactions of marine organisms with their environments are dramatically different than those of terrestrial species inhabiting landscapes. Physiology, dispersal, and fitness of marine species are tightly coupled to many scales of pelagic and benthic habitat heterogeneity as the nearly neutrally buoyant organisms make dramatic ontogenetic habitat transitions often required to complete their life cycles.
Conditional Transformation Models
Creators: name: Hothorn, Torsten
name: Kneib, Thomas
name: Bühlmann, Peter
Publisher: name: arXiv
Year: 2012
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences
subject: 62H12, 62G08, 62J02, 62J07

description: The ultimate goal of regression analysis is to obtain information about the conditional distribution of a response given a set of explanatory variables. This goal is, however, seldom achieved because most established regression models only estimate the conditional mean as a function of the explanatory variables and assume that higher moments are not affected by the regressors. The underlying reason for such a restriction is the assumption of additivity of signal and noise. We propose to relax this common assumption in the framework of transformation models. The novel class of semiparametric regression models proposed herein allows transformation functions to depend on explanatory variables. These transformation functions are estimated by regularised optimisation of scoring rules for probabilistic forecasts, e.g. the continuous ranked probability score. The corresponding estimated conditional distribution functions are consistent. Conditional transformation models are potentially useful for describing possible heteroscedasticity, comparing spatially varying distributions, identifying extreme events, deriving prediction intervals and selecting variables beyond mean regression effects. An empirical investigation based on a heteroscedastic varying coefficient simulation model demonstrates that semiparametric estimation of conditional distribution functions can be more beneficial than kernel-based non-parametric approaches or parametric generalised additive models for location, scale and shape.
Fermion bag solutions to some sign problems in four-fermion field theories
Creators: name: Chandrasekharan, Shailesh
name: Li, Anyi
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Lattice four-fermion models containing $N$ flavors of staggered fermions, that are invariant under $Z_2$ and U(1) chiral symmetries, are known to suffer from sign problems when formulated using the auxiliary field approach. Although these problems have been ignored in previous studies, they can be severe. Here we show that the sign problems disappear when the models are formulated in the fermion bag approach, allowing us to solve them rigorously for the first time.
description: references added
Metallic Nanoparticles and their Application in Heterogeneous Catalysis for Environmental Sciences
Creators: name: DEMIRCI, CANSUNUR
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: This thesis provides a comprehensive concept on how catalysis can tackle climate change and global warming by reducing greenhouse gases using three different approaches. In a first approach, gold nanoparticles were synthesized by means of a colloidal synthesis method and subsequently transformed to 3D gold structures, which allowed for the selective oxidative coupling of methanol to methyl formate and by this, reducing the emission of carbon dioxide (CO2) as a side-product. In a second approach, the wetness incipient impregnation method was utilized to obtain a palladium catalyst supported on aluminum oxide, which was investigated for its activity in the lean methane oxidation at elevated pressures and temperatures. Elevated pressures allowed overall higher combustion rates of methane to CO2, which is, in perspective, less harmful as a greenhouse gas than methane. The last approach tackled the reduction of CO2, using this greenhouse gas as a feedstock to reduce it electrochemically over nanoparticulate copper and gold catalyst, which were synthesized using the chemical solution deposition method followed by an in-situ electrochemical reduction. The final products of this reaction can be hydrocarbons, which can be utilized as fuels or chemicals. All in all, the idea was to find catalysts and methods to contribute to the reduction of potential greenhouse gases and finally closing the carbon cycle for a more sustainable and greener future of planet Earth.
Citizen's Attitudes about Privacy While Accessing Government Websites: Results of an Online Study
Creators: name: Stolfo, Salvatore
name: Johnson, Eric J.
name: Pavlicic, Tomislav
name: Jan, Stephen
Publisher: name: Columbia University
Year: 2003
Subjects: Computer science

description: This paper reports the results of an investigation on citizens' attitudes and concerns regarding privacy and security on the Web, in general, and on the government websites they may visit, in particular. We examine to what extent those concerns can be alleviated by using a Secure Private Portal that protects citizen's personally identifying information when accessing government websites. The research project had two main goals: (a) to develop a comprehensive psychological instrument to assess citizens' attitudes and concerns regarding privacy and security on the Web; (b) to test the impact a Secure Private Portal may have on those concerns and on the way citizens use Government Websites. In order to accomplish these goals researchers from Columbia Business School and from Columbia departments of Computer Science and Psychology, developed and ran a web based survey. Participants were recruited using online advertising through Google.com and provided their responses on the web. Early analyses of the results indicate a very high level of citizens' concerns regarding privacy and security of their personal data. Some of the concerns can appropriately be addressed only by fundamental policy changes. Furthermore, the results suggest that citizens perceive those sites which use secure portals as much safer and are more likely to visit them again. The results may indicate a new strategy for the presentation and design of government websites.
title: The Russian experience of collecting industry research data in the Barents Se ademersal fishery
Creators: name: Drevetnyak, K. V.
name: Shamray, E. A.
name: Lepesevich, Yu. M.
Publisher: name: ASC 2009 - Theme session L
Year: 2024
Subjects: Fisheries and aquaculture

description: No abstracts are to be cited without prior reference to the author.The Barents Sea is an important demersal fishery area for Northwestern Russia and Norway. The key species in bottom trawl fishery are cod, haddock, saithe, catfishes, Greenland halibut, redfishes etc. Russian demersal fishery primarily targets cod, catches of which make up about 70% of the total Russian catch in the Barents Sea. Russian cod fishery is conducted all the year round in the entire Barents Sea. Length and age of caught fish depend on the season and fishing area. Russian cod fishery is mainly conducted by large and medium-size freezing trawlers (over 200 vessels) with production facilities onboard and cruise duration exceeding 1 month, which denies the possibility to collect data during port calls. Russian trawlers fishing for cod in the Norwegian Economic Zone use 135 mm mesh, while those working in other Barents Sea areas use 125 mm mesh. This also results in differences in length and age composition of catches. With all this in view, PINRO has developed different schemes for collecting biological and industry research data on Russian cod fishery. The paper gives a detailed description of schemes used for collecting industry research data on Russian cod fishery. All types of industry research data are presented and their use for stock assessment and other managerial purposes is discussed.
Exploring a law firm business model to improve access to justice and decrease lawyer dissatisfaction
Creators: name: Pilliar, Andrew
Publisher: name: University of British Columbia
Year: 2012

description: Access to justice, particularly access to civil legal services, is a well-recognized problem for the Canadian legal system, with a recent estimate suggesting that 44.6 per cent of Canadians over the age of 18 – approximately 11.6 million people – have experienced a civil legal problem over the last three years, but also that less than 10 per cent of those individuals obtained legal assistance for that problem. Another problem for the Canadian legal system is the high rate of dissatisfaction among young lawyers – particularly the high rate of attrition among women and minorities. This thesis suggests a corrective for both these problems: an innovative type of law firm that provides accessible civil legal services while also providing an attractive work environment for lawyers. Through a case study of Pivot Legal LLP, a small firm formerly located in Vancouver’s Downtown Eastside, this thesis examines whether it is possible to run a sustainable legal practice that includes providing legal services to low- and middle-income individuals. Based on this case study, there is reason to believe that an innovative law firm model that provides low cost legal services is possible and would be a useful contribution to other efforts to improve access to justice.
Noncommutative gravity coupled to fermions: second order expansion via Seiberg-Witten map
Creators: name: Aschieri, Paolo
name: Castellani, Leonardo
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We use the Seiberg-Witten map (SW map) to expand noncommutative gravity coupled to fermions in terms of ordinary commuting fields. The action is invariant under general coordinate transformations and local Lorentz rotations, and has the same degrees of freedom as the commutative gravity action. The expansion is given up to second order in the noncommutativity parameter θ. A geometric reformulation and generalization of the SW map is presented that applies to any abelian twist. Compatibility of the map with hermiticity and charge conjugation conditions is proven. The action is shown to be real and invariant under charge conjugation at all orders in θ. This implies the bosonic part of the action to be even in θ, while the fermionic part is even in θ for Majorana fermions.
description: 27 pages, LaTeX. Revised version with proof of charge conjugation symmetry of the NC action and its parity under theta --> - theta (see new sect. 2.6, sect. 6 and app. B). References added. arXiv admin note: substantial text overlap with arXiv:0902.3817
Improving time upscaling of instantaneous evapotranspiration based on machine learning models
Creators: name: Yang, Danni
name: Yang, Shanshan
name: Huang, Jiaojiao
name: Zhang, Shuyu
name: Zhang, Sha
name: Zhang, Jiahua
name: Bai, Yun
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Hematology
subject: Virology

description: Evapotranspiration (ET) plays a crucial role in the global water and energy cycle. Upscaling instantaneous ET (ETi) to daily ET (ETd) is vital for thermal-based ET estimation. Conventional methods – such as the constant evaporative fraction method (ConEF), radiation-based method, and evaporative ratio method – often overlook environmental factors, leading to biased estimates of ETd from ETi. To resolve this issue, this study aimed to assess four machine learning (ML) algorithms—XGBoost, LightGBM, AdaBoost, and Random Forest—to integrate meteorological and remote sensing data for upscaling ETi across 88 global flux sites. Each ML model was tested with eight different variable combinations. Results indicated that XGBoost exhibited the best performance, with a root mean square error (RMSE) generally below 13 W m−2 in estimating ETd from ETi. The best variable combination simultaneously considers evaporative fraction, available energy, meteorology factors, remote sensing albedo, normalized vegetation index, and leaf area index. Using this combination, the XGBoost model achieved an R2 = 0.88 and an RMSE = 12.33 W m−2, outperforming the ConEF method (R2 = 0.71 and RMSE = 18.86 W m−2) and its expansions. These findings support the application of ML models in ET upscaling, enabling ET estimation across large spatiotemporal scales.
Nodular pattern of bone marrow infiltration: frequent finding in immunosuppression-related EBV-associated large B-cell lymphomas
Creators: name: Sevilla, Deborah W.
name: Weeden, Erin M.
name: Alexander, Suzy
name: Vundavalli, Murty V.
name: Alobeid, Bachir
name: Bhagat, Govind
Publisher: name: Columbia University
Year: 2009
Subjects: Lymphomas
Epstein-Barr virus
Bone marrow
Cytogenetics

description: Different patterns of bone marrow (BM) infiltration by diffuse large B cell lymphomas (DLBCL) have been described. A pure nodular pattern is uncommon, and the pathologic features, as well as the clinical correlates of DLBCL manifesting this pattern in the BM have not been well characterized. We evaluated BM biopsies involved by large B cell lymphomas diagnosed at our institute over an 11-year period to assess the morphology, phenotype, cytogenetic abnormalities, and clinical features of cases associated with a nodular pattern. A distinct nodular pattern of BM involvement was noted in 14 out of 55 (25%) cases. Although both EBV+ and EBV−DLBCL with this pattern were identified, a pure nodular pattern was significantly more common in EBV+ DLBCL compared to EBV− DLBCL (8/9, 89% versus 6/46, 13%; P=0.00002). The majority of EBV+ DLBCL associated with a nodular pattern had distinctive morphologic features (polymorphic cellular infiltrate and pleomorphic cytology), and CD30 expression was more commonly observed in this group (P=0.0163). All EBV+ DLBCL and two out of six (33%) EBV− DLBCL had nongerminal center phenotypes. No recurrent cytogenetic abnormalities were detected in either group. Importantly, all EBV+ DLBCL occurred in individuals with immune dysfunction (organ transplant recipients, HIV infection) or in those >50 years of age. Our study indicates a much higher predilection for EBV+ DLBCL to involve the marrow in a nodular pattern compared to EBV− cases and highlights similarities in the morphologic pattern of BM involvement by previously recognized subsets of immunodeficiency-related EBV + lymphomas and the newer entity of “EBV+ DLBCL of the elderly.”
Percolation of Partially Interdependent Scale-free Networks
Creators: name: Zhou, Di
name: Gao, Jianxi
name: Stanley, H. Eugene
name: Havlin, Shlomo
Publisher: name: arXiv
Year: 2012
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: We study the percolation behavior of two interdependent scale-free (SF) networks under random failure of 1-$p$ fraction of nodes. Our results are based on numerical solutions of analytical expressions and simulations. We find that as the coupling strength between the two networks $q$ reduces from 1 (fully coupled) to 0 (no coupling), there exist two critical coupling strengths $q_1$ and $q_2$, which separate three different regions with different behavior of the giant component as a function of $p$. (i) For $q \geq q_1$, an abrupt collapse transition occurs at $p=p_c$. (ii) For $q_2 3$, $q_1$ decreases with increasing $λ$. $(b)$ In the hybrid transition, at the $q_2 < q < q_1$ region, the mutual giant component $P_{\infty}$ jumps discontinuously at $p=p^{jump}_c$ to a very small but non-zero value, and when reducing $p$, $P_{\infty}$ continuously approaches to 0 at $p_c = 0$ for $λ< 3$ and at $p_c > 0$ for $λ> 3$. Thus, the known theoretical $p_c=0$ for a single network with $λ\leqslant 3$ is expected to be valid also for strictly partial interdependent networks.
description: 20 pages, 17 figures
Template-based reverse engineering of parametric CAD models from point clouds
Creators: name: SHAH, GHAZANFAR ALI
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: Even if many Reverse Engineering techniques exist to reconstruct real objects in 3D, very few are able to deal directly and efficiently with the reconstruction of editable CAD models of assemblies of mechanical parts that can be used in the stages of Product Development Processes (PDP). In the absence of suitable segmentation tools, these approaches struggle to identify and reconstruct model the different parts that make up the assembly. The thesis aims to develop a new Reverse Engineering technique for the reconstruction of editable CAD models of mechanical parts? assemblies. The originality lies in the use of a Simulated Annealing-based fitting technique optimization process that leverages a two-level filtering able to capture and manage the boundaries of the parts? geometries inside the overall point cloud to allow for interface detection and local fitting of a part template to the point cloud. The proposed method uses various types of data (e.g. clouds of points, CAD models possibly stored in database together with the associated best parameter configurations for the fitting process). The approach is modular and integrates a sensitivity analysis to characterize the impact of the variations of the parameters of a CAD model on the evolution of the deviation between the CAD model itself and the point cloud to be fitted. The evaluation of the proposed approach is performed using both real scanned point clouds and as-scanned virtually generated point clouds which incorporate several artifacts that could appear with a real scanner. Results cover several Industry 4.0 related application scenarios, ranging from the global fitting of a single part to the update of a complete Digital Mock-Up embedding assembly constraints. The proposed approach presents good capacities to help maintaining the coherence between a product/system and its digital twin.