cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Anemia and adverse outcomes in pregnancy: subgroup analysis of the CLIP cluster-randomized trial in India
Creators: name: Bone, Jeffrey N.
name: Bellad, Mrutyunjaya
name: Goudar, Shivaprasad
name: Mallapur, Ashalata
name: Charantimath, Umesh
name: Ramadurg, Umesh
name: Katageri, Geetanjali
name: Lesperance, Maria
name: Kinshella, Mai-Lei Woo
name: Suleman, Raiya
name: Vidler, Marianne
name: Sharma, Sumedha
name: Derman, Richard
name: Magee, Laura A.
name: Von Dadelszen, Peter
Publisher: name: BioMed Central
Year: 2022

description: Background Iron-deficiency anemia is a known risk factor for several adverse perinatal outcomes, but data on its impact on specific maternal morbidities is less robust. Further, information on associations between anemia in early pregnancy and subsequent outcomes are understudied. Methods The study population was derived from the Community Level Interventions for Pre-eclampsia (CLIP) trial in Karnataka State, India (NCT01911494). Included were women who were enrolled in either trial arm, delivered by trial end date, and had a baseline measure of hemoglobin (Hb). Anemia was classified by WHO standards into four groups: none (Hb ≥ 11 g/dL), mild (10.0 g/dL ≤ Hb < 11.0 g/dL), moderate (7.0 g/dL ≤ Hb < 10.0 g/dL) and severe (Hb < 7.0 g/dL). Targeted maximum likelihood estimation was used to estimate confounder-adjusted associations between anemia and a composite (and its components) of adverse maternal outcomes, including pregnancy hypertension. E-values were calculated to assess robustness to unmeasured confounding. Results Of 11,370 women included, 10,066 (88.5%) had anemia, that was mild (3690, 32.5%), moderate (6023, 53.0%), or severe (68, 0.6%). Almost all women (> 99%) reported taking iron supplements during pregnancy. Blood transfusions was more often administered to those with anemia that was mild (risk ratio [RR] 2.16, 95% confidence interval [CI] 1.31–3.56), moderate (RR 2.37, 95% CI 1.56–3.59), and severe (RR 5.70, 95% CI 3.00–10.85). No significant association was evident between anemia severity and haemorrhage (antepartum or postpartum) or sepsis, but there was a U-shaped association between anemia severity and pregnancy hypertension and pre-eclampsia specifically, with the lowest risk seen among those with mild or moderate anemia. Conclusion In Karnataka State, India, current management strategies for mild-moderate anemia in early pregnancy are associated with similar rates of adverse maternal or perinatal outcomes, and a lower risk of pregnancy hypertension and preeclampsia, compared with no anemia in early pregnancy. Future research should focus on risk mitigation for women with severe anemia, and the potential effect of iron supplementation for women with normal Hb in early pregnancy.
Applicazione della tecnologia sol-gel: sintesi di un materiale ibrido biocompatibile e studio delle proprietà spettroscopiche ed elettrochimiche del citocromo c incapsulato in un bio sol-gel
Creators: name: DERIU, DANIELA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2009
Subjects: subject: bio sol-gel; folding delle proteine; ibridi inorganici/organici; immobilizzazione delle proteine; citocromo c (cyt c)
subject: bio sol-gel
subject: folding delle proteine
subject: ibridi inorganici/organici
subject: immobilizzazione delle proteine
subject: citocromo c (cyt c)

description: 19. ciclo
Additional file 6 of Sitting less and moving more for improved metabolic and brain health in type 2 diabetes: ‘OPTIMISE your health’ trial protocol
Creators: name: Brakenridge, Christian J.
name: Gardiner, Paul A.
name: Grigg, Ruth V.
name: Winkler, Elisabeth A. H.
name: Fjeldsoe, Brianna S.
name: Schaumberg, Mia A.
name: Owen, Neville
name: Eakin, Elizabeth G.
name: Biddle, Stuart J. H.
name: Moodie, Marjory
name: Daly, Robin M.
name: Green, Daniel J.
name: Cohen, Neale
name: Gray, Len
name: Comans, Tracy
name: Buman, Matthew P.
name: Goode, Ana D.
name: Nguyen, Phuong
name: Gao, Lan
name: Healy, Genevieve N.
name: Dunstan, David W.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Additional file 6. Intervention strategy list.
Supplementary document for Ghost panorama using a convex mirror - 5489917.pdf
Creators: name: Ye, Zhiyuan
name: Wang, Hai-Bo
name: Xiong, Jun
name: Wang, Kaige
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Classical and Physical Optics
Photonics, Optoelectronics and Optical Communications

description: Supplement
Gallium nitride-based device simulation and development
Creators: name: RUSSO, STEFANO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2009
Subjects: subject: GaN; device simulation; drift-diffusion; HEMT; Schottky diode; Monte-Carlo
subject: GaN
subject: device simulation
subject: drift-diffusion
subject: HEMT
subject: Schottky diode
subject: Monte-Carlo

description: 20. ciclo
Additional file 7 of Sitting less and moving more for improved metabolic and brain health in type 2 diabetes: ‘OPTIMISE your health’ trial protocol
Creators: name: Brakenridge, Christian J.
name: Gardiner, Paul A.
name: Grigg, Ruth V.
name: Winkler, Elisabeth A. H.
name: Fjeldsoe, Brianna S.
name: Schaumberg, Mia A.
name: Owen, Neville
name: Eakin, Elizabeth G.
name: Biddle, Stuart J. H.
name: Moodie, Marjory
name: Daly, Robin M.
name: Green, Daniel J.
name: Cohen, Neale
name: Gray, Len
name: Comans, Tracy
name: Buman, Matthew P.
name: Goode, Ana D.
name: Nguyen, Phuong
name: Gao, Lan
name: Healy, Genevieve N.
name: Dunstan, David W.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Additional file 7. Health coaching script.
Additional file 8 of Sitting less and moving more for improved metabolic and brain health in type 2 diabetes: ‘OPTIMISE your health’ trial protocol
Creators: name: Brakenridge, Christian J.
name: Gardiner, Paul A.
name: Grigg, Ruth V.
name: Winkler, Elisabeth A. H.
name: Fjeldsoe, Brianna S.
name: Schaumberg, Mia A.
name: Owen, Neville
name: Eakin, Elizabeth G.
name: Biddle, Stuart J. H.
name: Moodie, Marjory
name: Daly, Robin M.
name: Green, Daniel J.
name: Cohen, Neale
name: Gray, Len
name: Comans, Tracy
name: Buman, Matthew P.
name: Goode, Ana D.
name: Nguyen, Phuong
name: Gao, Lan
name: Healy, Genevieve N.
name: Dunstan, David W.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Additional file 8. COVID-19 Snapshot Questionnaire.
Wandelprozesse verstehen und erfolgreicher gestalten
Creators: name: Eichhorn, Daniel
name: Lindenthal, Alexandra
name: Kristof, Kora
name: Hanke, Gerolf
Publisher: name: Umweltbundesamt
Year: 2019
Subjects: subject: Nachhaltigkeit
subject: Soziale Innovation
subject: transformation
subject: Wandel
subject: Exnovation
subject: Trends
subject: Allianzen
subject: Paradigmenwechsel
subject: Veränderungsprozesse
subject: Nachhaltigkeit | Strategien | Internationales

description: Seit einigen Jahren gewinnt das Schlagwort der â€ÌTransformationâ€Ì in umweltpolitischen Debatten an Bedeutung. Der Begriff verdeutlicht die Dimension und Eingriffstiefe des notwendigen Wandels von Gesellschaften in Richtung Nachhaltigkeit . Außerdem erlaubt er eine systemische Perspektive, mit der die Komplexität dieses Wandels verständlich wird. Das Hintergrundpapier wirft Licht auf den sperrigen Begriff der Transformation. Es verdeutlicht, warum es sinnvoll ist, nach dem â€ÌWieâ€Ì von erfolgreichen Wandelprozessen zu fragen. Zudem leitet es aus der Transformationsdebatte Handlungsmuster und -ansätze für umweltpolitische Akteure ab. Quelle: https://www.umweltbundesamt.de/
description: Seit einigen Jahren gewinnt das Schlagwort der „Transformation“ in umweltpolitischen Debatten an Bedeutung. Der Begriff verdeutlicht die Dimension und Eingriffstiefe des notwendigen Wandels von Gesellschaften in Richtung ⁠Nachhaltigkeit⁠. Außerdem erlaubt er eine systemische Perspektive, mit der die Komplexität dieses Wandels verständlich wird. Das Hintergrundpapier wirft Licht auf den sperrigen Begriff der Transformation. Es verdeutlicht, warum es sinnvoll ist, nach dem „Wie“ von erfolgreichen Wandelprozessen zu fragen. Zudem leitet es  aus der Transformationsdebatte Handlungsmuster und -ansätze für umweltpolitische Akteure ab.
title: Clonaggio, espressione e caratterizzazione della porzione solubile di Anaerobic induced protein A (sAniA) di Neisseria meningitidis
title: Cloning, expression and characterization of soluble fraction of Anaerobic induced protein A (sAniA) of Neisseria meningitidis
titleType: AlternativeTitle
Creators: name: NERI, ARIANNA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: nitrito reduttasi; ossido nitrico; denitrificazione; AniA; Neisseria meningitidis
subject: nitrito reduttasi
subject: ossido nitrico
subject: denitrificazione
subject: AniA
subject: Neisseria meningitidis

description: 20. ciclo
description: 1. Introduzione - 1.1 Infezione da N. meningitidis - 1.2 Neisseria meningitidis - 1.3 Fattori di virulenza - 1.4 Metabolismo dell'ossido nitrico in N. meningitidis - 1.5 Classi di nitrito reduttasi - 1.6 Struttura del dominio solubile e meccanismo catalitico di AniA - 1.7 Ruolo di AniA nella patogenesi di N. meningitidis - 1.8 Scopo della tesi . - 2. Materiali e Metodi - 2.1 Ceppi batterici e procedure colturali - 2.2 Estrazione del DNA di N. meningitidis e analisi della sequenza del gene aniA - 2.3 Clonaggio ed espressione della porzione solubile di AniA dai ceppi MC58 e 1332 - 2.4 Lisi dei batteri e purificazione di sAniA - 2.5 Preparazione del siero policlonale di coniglio e Western blotting - 2.6 Caratterizzazione biochimica di AniA - 2.6.1 Dosaggi di attività enzimatica a diversi pH - 2.6.2 Cinetica enzimatica di AniA - 2.7 Crescita in brodo e consumo del nitrito di ceppi di N. meningitidis di isolamento clinico. - 3. Risultati - 3.1 Analisi della sequenza nucleotidica e aminoacidica del gene aniA - 3.2 Clonaggio ed espressione della porzione solubile di AniA - 3.3 Espressione di AniA in ceppidi isolamento clinico - 3.4 Attività enzimatica di sAniA di MC58 in funzione del pH - 3.5 Caratterizzazione di sAniA di MC58 valutando l' ossidazione del ditionito - 3.4 Consumo di nitrito in ceppi di N. meningitidis di isolamento clinico. - 4. Discussione - Biblografia
Additional file 9 of Sitting less and moving more for improved metabolic and brain health in type 2 diabetes: ‘OPTIMISE your health’ trial protocol
Creators: name: Brakenridge, Christian J.
name: Gardiner, Paul A.
name: Grigg, Ruth V.
name: Winkler, Elisabeth A. H.
name: Fjeldsoe, Brianna S.
name: Schaumberg, Mia A.
name: Owen, Neville
name: Eakin, Elizabeth G.
name: Biddle, Stuart J. H.
name: Moodie, Marjory
name: Daly, Robin M.
name: Green, Daniel J.
name: Cohen, Neale
name: Gray, Len
name: Comans, Tracy
name: Buman, Matthew P.
name: Goode, Ana D.
name: Nguyen, Phuong
name: Gao, Lan
name: Healy, Genevieve N.
name: Dunstan, David W.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Additional file 9. Questionnaire measures.
Additional file 1 of Youth mental health and/or addiction concerns and service needs during the COVID-19 pandemic: a qualitative exploration of caregiver experiences and perspectives
Creators: name: Markoulakis, Roula
name: Da Silva, Andreina
name: Kodeeswaran, Sugy
name: Levitt, Anthony
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Additional participant quotations.
Supplementary document for Ghost panorama using a convex mirror - 5489917.pdf
Creators: name: Ye, Zhiyuan
name: Wang, Hai-Bo
name: Xiong, Jun
name: Wang, Kaige
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Classical and Physical Optics
Photonics, Optoelectronics and Optical Communications

description: Supplement
Plasma-Enabled Smart Nanoexosome Platform as Emerging Immunopathogenesis for Clinical Viral Infection
Creators: name: Mousavi, Seyyed Mojtaba
name: Hashemi, Seyyed Alireza
name: Gholami, Ahmad
name: Kalashgrani, Masoomeh Yari
name: Vijayakameswara Rao, Neralla
name: Omidifar, Navid
name: Hsiao, Wesley Wei-Wen
name: Lai, Chin Wei
name: Chiang, Wei-Hung
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2022

description: Smart nanoexosomes are nanosized structures enclosed in lipid bilayers that are structurally similar to the viruses released by a variety of cells, including the cells lining the respiratory system. Of particular importance, the interaction between smart nanoexosomes and viruses can be used to develop antiviral drugs and vaccines. It is possible that nanoexosomes will be utilized and antibodies will be acquired more successfully for the transmission of an immune response if reconvalescent plasma (CP) is used instead of reconvalescent plasma exosomes (CPExo) in this concept. Convalescent plasma contains billions of smart nanoexosomes capable of transporting a variety of molecules, including proteins, lipids, RNA and DNA among other viral infections. Smart nanoexosomes are released from virus-infected cells and play an important role in mediating communication between infected and uninfected cells. Infections use the formation, production and release of smart nanoexosomes to enhance the infection, transmission and intercellular diffusion of viruses. Cell-free smart nanoexosomes produced by mesenchymal stem cells (MSCs) could also be used as cell-free therapies in certain cases. Smart nanoexosomes produced by mesenchymal stem cells can also promote mitochondrial function and heal lung injury. They can reduce cytokine storms and restore the suppression of host antiviral defenses weakened by viral infections. This study examines the benefits of smart nanoexosomes and their roles in viral transmission, infection, treatment, drug delivery and clinical applications. We also explore some potential future applications for smart nanoexosomes in the treatment of viral infections.
tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch
Creators: name: Grigg, Jason
name: Price, Ian R.
name: Ke, Ailong
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2022

description: RNAs are prone to misfolding and are often more challenging to crystallize and phase than proteins. Here, we demonstrate that tRNA fusion can streamline the crystallization and structure determination of target RNA molecules. This strategy was applied to the T-box riboswitch system to capture a dynamic interaction between the tRNA 3′-UCCA tail and the T-box antiterminator, which senses aminoacylation. We fused the T-box antiterminator domain to the tRNA anticodon arm to capture the intended interaction through crystal packing. This approach drastically improved the probability of crystallization and successful phasing. Multiple structure snapshots captured the antiterminator loop in an open conformation with some resemblance to that observed in the recent co-crystal structures of the full-length T box riboswitch–tRNA complex, which contrasts the resting, closed conformation antiterminator observed in an earlier NMR study. The anticipated tRNA acceptor–antiterminator interaction was captured in a low-resolution crystal structure. These structures combined with our previous success using prohead RNA–tRNA fusions demonstrates tRNA fusion is a powerful method in RNA structure determination.
Revealing the Invisible: a comparative analysis of the underwater heritage management in the Mediterranean context
Creators: name: De Vivo, Caterina
Publisher: name: IMT Alti Studi Lucca
Year: 2015
Subjects: NX Arts in general

description: This work looks at the management of the underwater archaeological heritage in the Mediterranean context. Choosing two case studies from France (Marseille and Arles), Italy (Naples and Sicily), and Spain (Cartagena and Catalonia), we analyzed what underwater archaeological heritage is, how the underwater archaeological heritage is managed considering all the stakeholders involved in the construction of the heritage, its dissemination to the public, and, especially, how this heritage is perceived, if it is perceived, by society, bearing in mind that "cultural heritage" in general is not an objective and given concept. In the selection of the cases, both the sites where the underwater heritage is preserved in situ (which means under the surface of the water) and on land (e.g. in museums) were considered. At the beginning of the work we identified invisibility as the main problem related to the communication of the underwater heritage to the public. Nevertheless, it emerged that most cases were unsuccessful in generating awareness of the existence of underwater heritage in the public because of issues that may be related to management of the archaeological heritage in general. In some cases, however, a problem in the institutionalization of underwater archaeology as a discipline was registered, and we demonstrated that, at least in the three considered countries, the process of "heritagization" of the underwater archaeological remains is probably not completed. Clear narratives built around a clear interpretation of the archaeological data, and close collaboration between all the stakeholders involved in the heritage construction process, recorded both in Arles and Cartagena cases, proved to be fundamental factors for helping the public develop an excellent rapport with the heritage and for giving archaeological heritage a shared meaning. This work aims to enrich the Public Archaeology discourse on the importance of engaging local communities and visitors in the "heritage production" process, as well as on the need to find ever more and ever newer strategies to communicate the historical heritage to society. To develop this analysis a methodology borrowed from the Sociology of Culture was used. Griswold's Cultural Diamond and Schudson's dimensions in particular were used to explicate the relations between underwater heritage as a cultural object and society, and the power of underwater heritage as a cultural construct.
Additional file 1 of Experience of discrimination during COVID-19 pandemic: the impact of public health measures and psychological distress among refugees and other migrants in Europe
Creators: name: Marchi, Mattia
name: Magarini, Federica Maria
name: Chiarenza, Antonio
name: Galeazzi, Gian Maria
name: Paloma, Virginia
name: Garrido, Rocío
name: Ioannidi, Elisabeth
name: Vassilikou, Katerina
name: de Matos, Margarida Gaspar
name: Gaspar, Tania
name: Guedes, Fabio Botelho
name: Primdahl, Nina Langer
name: Skovdal, Morten
name: Murphy, Rebecca
name: Durbeej, Natalie
name: Osman, Fatumo
name: Watters, Charles
name: van den Muijsenbergh, Maria
name: Sturm, Gesine
name: Oulahal, Rachid
name: Padilla, Beatriz
name: Willems, Sara
name: Spiritus-Beerden, Eva
name: Verelst, An
name: Derluyn, Ilse
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1.
Additional file 1 of Evaluating agreement between bodies of evidence from randomized controlled trials and cohort studies in medical research: a meta-epidemiological study
Creators: name: Bröckelmann, Nils
name: Balduzzi, Sara
name: Harms, Louisa
name: Beyerbach, Jessica
name: Petropoulou, Maria
name: Kubiak, Charlotte
name: Wolkewitz, Martin
name: Meerpohl, Joerg J.
name: Schwingshackl, Lukas
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Additional file 1: Appendix S1. Search strategy for systematic reviews. Figure S1. Flow diagram, identification of systematic reviews. Table S1. Criteria for rating PI/ECO-similarity degree. Table S2. Transformations made to the original data extraction. Table S3. Reasons for exclusion of systematic reviews. Table S4. Characteristics of included BoE from RCTs. Table S5. Certainty of the evidence and risk of bias for BoE from RCTs. Table S6. Characteristics of BoE from cohort studies. Table S7. Risk of bias and certainty of the evidence for BoE from cohort studies. Table S8. Heat map: instruments used for the assessment of risk of bias for BoE from RCTs and cohort studies. Table S9. Ratings of PI/ECO-similarity degree for included BoE-pairs. Table S10. Effect estimates and statistical heterogeneity for meta-analyses of RCTs and cohort studies. Figure S2a. Forest plot, analysis by population similarity degree. Figure S2b. Forest plot, analysis by intervention/ exposure similarity degree. Figure S2c. Forest plot, analysis by comparator similarity degree. Figure S2d. Forest plot, analysis by outcome similarity degree. Figure S3. Forest plot, analysis by intervention-type. Figure S3a. Forest plot, analysis of invasive procedures, stratified by PI/ECO-similarity degree. Figure S3b. Forest plot, analysis of drugs as intervention, stratified by PI/ECO-similarity degree. Figure S3c. Forest plot, analysis of nutrition as intervention, stratified by PI/ECO-similarity degree. Figure S3d. Forest plot, analysis of vaccines as intervention, stratified by PI/ECO-similarity degree. Figure S3e. Forest plot, analysis of birth assistance as intervention, stratified by PI/ECO-similarity degree. Figure S4. Forest plot, analysis of nutrition as intervention: Vitamin D/ Calcium as intervention vs. other nutrition-interventions. Figure S5. Forest plot, analysis by outcome-category. Figure S6. Sensitivity analysis: one BoE-pair per systematic review. Figure S7. Sensitivity analysis by direction of cohort study summary effect estimate.
The land portal and open development Mekong: developing a localization framework for creating a sustainable information ecosystem on land
Creators: name: Subirats, Imma
name: Meggiolaro, Laura
Publisher: name: F1000Research
Year: 2016

description: Countries in the Mekong Delta share features and a historical land governance context, such as efforts to formalize land titles and a transition from an authoritarian or command economy to post-socialist economies. In an effort to address these complex challenges, the East-West Management Institute’s Open Development Initiative (EWMI-ODI) established the Open Development Mekong (OD Mekong) platform  to capture and facilitate moderated crowd-sourced data-on a wide range of development sectors, including land, transcending national borders.

As part of it localization strategy, the Land Portal is taking a collaborative approach to partner with existing information service providers such ODM and transform their land-related information into Linked Open Data, the Land Portal is working with a range of partners who are committed to the common goal of making information accessible, open, and usable by everyone.

As part of its strategy, the Land Portal aims to assist ODM to become fully open data compliant to better structure and expose land governance data by offering capacity building and technical support. Following this pattern, ODM will soon develop its innovative technical infrastructure and will become the first web platform in the region to promote standards, tools and good practices around (Linked) Open Data.
The microsatellite instability phenotype in human colorectal carcinoma
Creators: name: PINO, MARIA SIMONA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: instabilità microsatellitare; carcinoma; colon-retto; neoplasia; MisMatch Repair (MMR)
subject: instabilità microsatellitare
subject: carcinoma
subject: colon-retto
subject: neoplasia
subject: MisMatch Repair (MMR)

description: 22. ciclo
description: Chapter 1:Outline of the Thesis Chapter 2:General Introduction Chapter 3: Lynch Syndrome: Germline Mutation in MMR Genes Chapter 4: Deficient DNA Mismatch Repair in Lynch Syndrome Associated Colorectal Adenomas Chapter 5: The Role of Transforming Growth Factor-β in Human Cancer Chapter 6: The Epithelial to Mesenchymal Transition in Colon Cancer Cells with Microsatellite Instability Chapter 7: Concluding Remarks
Pflanzenschutz mit Luftfahrzeugen
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Anwendung von Pflanzenschutzmitteln mit Luftfahrzeugen
subject: Insektizid
subject: Umweltgefährdung
subject: Luftfahrzeug
subject: Waldschutz
subject: Ausbringung von Pflanzenschutzmitteln aus der Luft
subject: Umweltrisiko
subject: Chemikalien
subject: Chemicals

description: Wegen neuer Anwendungsbestimmungen für die Pflanzenschutzmittel Karate Forst flüssig und Dipel ES entscheiden ab sofort die Bundesländer allein über die Genehmigung der Ausbringung mit Luftfahrzeugen in Naturschutzgebieten. Damit steigt die Verantwortung der Länder für den Schutz der Umwelt vor Pflanzenschutzmitteln, besonders im Hinblick auf naturschutzrechtlich geschützte Arten und Lebensräume. Mit dem vorliegenden Papier geben das Bundesamt für Naturschutz (⁠BfN⁠) und das Umweltbundesamt (⁠UBA⁠) Hinweise, welche ökotoxikologischen und naturschutzfachlichen Fragen bei der Genehmigung zu beachten sind.
Additional file 1 of Inhibition of ChREBP ubiquitination via the ROS/Akt-dependent downregulation of Smurf2 contributes to lysophosphatidic acid-induced fibrosis in renal mesangial cells
Creators: name: Kim, Donghee
name: Nam, Ga-Young
name: Seo, Eunhui
name: Jun, Hee-Sook
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Computational Biology

description: Additional file 1: Fig. S1. Glomerular expression of ChREBP and α–smooth muscle actin (α-SMA) in wild type mice (related to Fig. 1C). Fig. S2. The LPA-induced expression of ChREBP protein is partially mediated via transcription in SV40 MES13 cells. Fig. S3. Transfection efficiency of ChREBP and Smurf2 overexpression in SV40 MES13 cells. Fig. S4. ChREBP mediates the LPA-induced proliferation of SV40 MES13 cells. Table S1. Primers used for quantitative real-time PCR.
Additional file 1 of Survival and predictors of asphyxia among neonates admitted in neonatal intensive care units of public hospitals of Addis Ababa, Ethiopia, 2021: a retrospective follow-up study
Creators: name: Getaneh, Fekadeselassie Belege
name: sebsbie, Girum
name: Adimasu, Mekonen
name: Misganaw, Natnael Moges
name: Jember, Desalegn Abebaw
name: Mihretie, Dires Birhanu
name: Abeway, Shiferaw
name: Bitew, Zebenay Workneh
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1.
Understanding the Influence of Community-Level Determinants on Children’s Social and Emotional Well-Being: A Systems Science and Participatory Approach
Creators: name: Poon, Brenda T.
name: Atchison, Chris, 1971-
name: Kwan, Amanda
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2022

description: Healthy social and emotional development and longer-term outcomes for children are shaped by factors across the multiple levels (micro, meso, exo, macro) of a child’s environment. By employing a novel systems science and participatory approach, we were able to co-produce a series of causal loop diagrams that detail the complex relationships between variables operating at the community or neighborhood environment level (e.g., features of the built environment such as: housing type, access, availability, and location; parks and greenspace, facilities such as community services, and other service infrastructure such as transit), and highlight the individual and collective impacts these relationships can have on the subsystem surrounding a child’s social and emotional well-being. Our approach provides a unique lens of knowledge through which communities can identify key leverage points for action and (re)design of community spaces, practices, and policy.
Supplementary document for Extended range and aberration-free autofocusing via remote focusing and sequence-dependent learning - 5490213.pdf
Creators: name: Cui, Jiahe
name: Turcotte, Raphaël
name: Emptage, Nigel
name: Booth, Martin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Optical Technology

description: Supplement 1
Additional file 1 of Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial
Creators: name: Rüddel, Hendrik
name: Thomas-Rüddel, Daniel O.
name: Reinhart, Konrad
name: Bach, Friedhelm
name: Gerlach, Herwig
name: Lindner, Matthias
name: Marshall, John C.
name: Simon, Philipp
name: Weiss, Manfred
name: Bloos, Frank
name: Schwarzkopf, Daniel
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Science Policy

description: Additional file 1. Supplemental Figures. SFigure 1. Calibration belt of the risk-adjustment-model for 28-day-mortality. The figure shows observed 28-day mortality (y-axis) compared to model based estimates of expected 28-day mortality (x-axis). SFigure 2. Flow-diagram of the study. SFigure 3. Panel a: Timing of start of antimicrobial treatment in relation to onset of sepsis. Panel b: Timing of surgical source control in relation to onset of sepsis. Panel c: Cumulative proportion of patients receiving antimicrobial treatment after onset of sepsis within the first 48 hours. Panel d: Cumulative proportion of patients receiving surgical source control after onset of sepsis within the first 48 hours. SFigure 4. Crude mortality and predicted mortality depending on success of surgical source control. Presented are the risk (bars) and predicted risk (lines) across a range of time after onset of sepsis. Bold lines present the predicted risk with 95% confidence interval for a typical patient from a model adjusting for covariates, dotted lines present the predicted risk with 95% confidence interval from a model without adjusting for covariates. The effect of timing was tested for linearity by fractional polynomials at significance level 0.05; timing was treated as linear, since no significant deviation from linearity was found. Risk-adjusted OR with 95% CI: 0.991 [0.978, 1.005], p = 0.197; raw OR with 95% CI: 0.982 [0.971, 0.994], p = 0.003. N = 1595 cases did undergo surgical source control within 48 hours, of which 1592 cases had complete data on outcome and covariates for analysis. The risk-adjustment model involved the following covariates: age and gender, origin of infection, location of the patient at the onset of sepsis, focus of infection, microbiological confirmation of infection, study phase (trial vs. surveillance phase), and group the hospital was randomized to (intervention vs. control).
Implications of legal protection and quality management of the traditional regional food heritage in the EU: the case of a PDO Oscypek Cheese from Southern Poland
Creators: name: Jarosik, Magdalena
Publisher: name: IMT Alti Studi Lucca
Year: 2015
Subjects: NX Arts in general

description: Food safety and quality in the EU has been a widely discussed topic since the creation of the European Single Market. The way of food from the production place to the plates of consumers became increasingly longer and complicated, providing more chances of food contamination by hazardous substances and bacteria. This poses a potential threat to peoples' health and appropriate legal measures needed to be taken in order to protect both health and other interests of consumers. Currently, locally produced food from locally-grown products is believed to be a healthier and safer alternative to the massproduced food goods. This idea, together with the growing interest in food and nutrition studies, regional cultures, local folklore, as well as dynamic development of gastronomic tourism, gave rise to the popularity of traditional regional foods as authentic, safe, natural, and high quality expressions of regional gastronomic heritage. Within this framework, the research investigates in what ways EU legal food safety and quality regulations may impact the safeguarding of gastronomic heritage of the European regions. Through an interdisciplinary analysis, it analyzes what are the potential interferences between the EU Food Safety regulations, the EU Quality Schemes for Agricultural Products (particularly considering the Protected Designation of Origin), and UNESCO frameworks for tangible and intangible heritage. The main question to answer is if a GI may conflict with food heritage protection, in what ways it impacts the producers and the protected product itself, and if this is what is currently happening in case of a PDO oscypek cheese from Southern Poland. Through qualitative in-depth interviews with oscypek producers and relevant authorities on local, regional and national levels, this analysis provides an overview of dynamics within highlander community and attitudes toward the impact of a GI status on future of this touristic product and intangible practice. The research is concluded with recommendations for future development for production, management and promotion of this culturally significant food heritage and tradition.
Ardea: le fortificazioni urbane e del Castrum Inui
Creators: name: CIPRIANI, GIULIA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: fortificazioni; Aggere; Ardea; Castrum Inui
subject: fortificazioni
subject: Aggere
subject: Ardea
subject: Castrum Inui

description: 21. ciclo
description: Introduzione - Premessa geomorfologica - Storia degli studi e degli scavi - “La città prima della città” - La nascita della città: la realizzazione degli aggeri - Ardea dall’età arcaica all’età repubblicana - Il VI secolo a.C. - Il V secolo a.C. - Il IV secolo a.C.: la costruzione delle fortificazioni in opera quadrata - Dal III secolo a.C. alla fine dell’età repubblicana - Ardea in età imperiale - Analisi e schedatura dei tratti visibili delle fortificazioni urbane e del Castrum Inui - Mura urbane in opera quadrata - Mura del Castrum Inui in opera quadrata - Considerazioni finali e sviluppi di ricerca - Le fonti letterarie - Bibliografia
Supplementary document for Extended range and aberration-free autofocusing via remote focusing and sequence-dependent learning - 5490213.pdf
Creators: name: Cui, Jiahe
name: Turcotte, Raphaël
name: Emptage, Nigel
name: Booth, Martin
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Optical Technology

description: Supplement 1
Additional file 2 of Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial
Creators: name: Rüddel, Hendrik
name: Thomas-Rüddel, Daniel O.
name: Reinhart, Konrad
name: Bach, Friedhelm
name: Gerlach, Herwig
name: Lindner, Matthias
name: Marshall, John C.
name: Simon, Philipp
name: Weiss, Manfred
name: Bloos, Frank
name: Schwarzkopf, Daniel
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Science Policy

description: Additional file 2. Supplemental Tables. STable 1. Risk-adjustment-model for 28-day mortality excluding variables on severity of critical illness. STable 2. Risk-adjustment-model for 28-day mortality including variables on severity of critical illness. STable 3. Characteristics of participating hospitals. STable 4. Description of cases with timing of antimicrobial therapy before sepsis onset or after more than 48 hours. STable 5. Description of cases with timing of surgical source control before sepsis onset or after more than 48 hours. STable 6. Analysis of combined effects of delay in antimicrobial therapy and delay in surgical source control. STable 7. Effects of indicators of quality of anti-infective therapy on hospital length-of-stay of hospital survivors. STable 8. Sensitivity analysis on effects of indicators on quality of anti-infective therapy on 28-day-mortality adjusting for covariates including measures on severity of critical illness.
Additional file 1 of The impact of ‘grounds’ on abortion-related outcomes: a synthesis of legal and health evidence
Creators: name: de Londras, Fiona
name: Cleeve, Amanda
name: Rodriguez, Maria I.
name: Lavelanet, Antonella F.
Publisher: name: figshare
Year: 2022
Subjects: subject: Law
subject: FOS: Law

description: Additional file 1: Suppl Table 1. Evidence table: Impact on the intervention on abortion seekers. Supple Table 2. Evidence Table: The impact of the intervention on health professionals.
Safety considerations in the evolving legal landscape of psychedelic-assisted psychotherapy
Creators: name: Mocanu, Victor
name: Mackay, Lindsay
name: Christie, Devon
name: Argento, Elena
Publisher: name: BioMed Central
Year: 2022

description: International drug policy is rapidly evolving in tandem with promising evidence for psychedelic-assisted psychotherapy (PAP) in treating a range of mental health conditions. Canada is among the countries increasingly expanding access to psychedelic substances for therapeutic purposes. The 8-year ban on medical exemptions through the Canadian Special Access Programme was recently reversed in January 2022 and the first exemptions for legal possession and personal use of psilocybin mushrooms were granted in 2020, nearly 50 years since their criminalization. In view of the evolving evidence base and regulatory landscape for PAP illustrated by recent shifts in Canadian and international drug policy, this piece seeks to clarify the special range of factors which ought to be considered to safely expand access to psychedelics. Streamlining access to safe and evidence-based compassionate use of PAP will provide a timely treatment option to those currently in need while encouraging further research and outcome surveillance to refine best practices.
From Human Mobility to Building Functions: A Deep Learning Approach for Urban Building Classification in Megacity Tokyo
Creators: name: Yao, Yao
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 370499
subject: Geoinformatics not elsewhere classified

description: Content1.STAF-NetThe "data" folder contains the example data. "Sample_TRAIN.csv" and ""Sample_TEST.csv" "is the dataset for model training and evaluation, including the human mobility timeseries and poi embedding results of the samples.The "data_provider" contains that code files used to load the dataset file.The "models" folder is the model structure defined using Pytorch.The "exp" floder contains model experiment file, which is used to classify experiments.The "utils" folder is the toolkit required for modeling training.The "Layers" folder is some of the model layers that make up the model.The "Run.py" is the code that executes the model training. It is also the entry point of the main program. The method of calling the program has been noted in the code.The “requirements.txt” file is the dependencies that are needed to run the code. Install the runtime environment with the command "pip install -r requirements.txt".The environment required for this project includes:Python 3.8; Pytorch 2.0; 2.Building dataBuilding data.zip provides the building function identifying results of buildings in 23 districts of Tokyo.
Perspectives on Italian prepaid cards market
Creators: name: PELILLI, DAVID
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2009
Subjects: subject: electronic money; card payment use; prepaid cards; payment instruments adoption; TPB models; TAM models
subject: electronic money
subject: card payment use
subject: prepaid cards
subject: payment instruments adoption
subject: TPB models
subject: TAM models

description: 19. ciclo
Molar and partial molar thermodynamic functions of [BMIm]BF4/water mixture (Gibbs free energy, entropy and enthalpy)
Creators: name: Kaneko, Kazuyoshi
name: Kitawaki, Kyohei
name: Mori, Tomoyoshi
name: Yoshimura, Yukihiro
name: Shimizu, Akio
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: The viscosity of a 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIm]BF4)/water mixture has been reported to be less than one-half that of pure [BMIm]BF4 for water mole fraction (χw) of 0.3, even though the liquid structure of [BMIm]BF4 has been reported to be similar to that of pure [BMIm]BF4 for 0 ≤ χw ≤ 0.7. To investigate the relationship between the liquid structure and viscosity, the water content dependence of the viscosity is discussed in terms of the molar and partial molar thermodynamic functions calculated from the density and viscosity of the [BMIm]BF4/water mixture. A schematic model is then proposed based on the results. In the water fraction region of 0–0.3, water molecules enter into the liquid structure of [BMIm]BF4. Water molecules do not interact strongly with [BMIm]BF4 and have much higher mobility than [BMIm]BF4; therefore, it is expected that the water molecules enhance the fluidity of [BMIm]BF4 as a lubricant.
Supplementary document for Ptychography-based high-throughput lensless on-chip microscopy via incremental proximal algorithms - 5490287.pdf
Creators: name: Yue, Huang
name: Jiang, Shaowei
name: Wang, Ruihai
name: Song, Pengming
name: Zhang, Jian
name: Zheng, Guoan
name: ji, xiangyang
name: zhang, yongbing
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: The derivation of our algorithms and additional simulations
Screening for biofilm formation of E. coli pathotypes and determination of the effect of antimicrobial peptides on biofilm formation by automated fluorescence microscopy
Creators: name: Schiebel, Juliane
name: Böhm, Alexander
name: Nitschke, Jörg
name: Weinreich, Jörg
name: Rapsch, Karsten
name: Rödiger, Stefan
name: Schierack, Peter
Publisher: name: F1000Research
Year: 2016

description: Introduction
Biofilms are communities of microorganisms, which live in a self-produced matrix of extracellular polymeric substances. Biofilm mediated infections are hard to treat due to their resistance to immune defense and antibiotics. Therefore it is important to develop tools to investigate biofilms for therapy improvement or to find new antimicrobial substances.

Objectives
The aim of this work is to build a fully automated large-scale screening platform, which can be used to examine the ability of biofilm formation under different culture conditions. Most importantly we aim to determine the effects of antimicrobial substances. As a first application biofilm formation of different E. coli pathotypes was examined. In addition we determined the effect of several antimicrobial peptides (AMP) on biofilm formation.

Conclusions
With our VideoScan technology it is possible to study biofilms in a fully automated large-scale screening. With this technique we could detect a considerable number of biofilm formers out of 186 E. coli strains. In addition we demonstrated the bactericidal effect of different AMP resulting in inhibition of biofilm formation. In a next step classification of biofilm formation e.g. weak or strong biofilm former will be developed based on fluorescence intensity measurements.
The Sanctuary of Artemis Orthia (Sparta)
Creators: name: Daniels, Megan
Publisher: name: Database of Religious History (DRH)
Year: 2022

description: The sanctuary to the goddess Orthia (later conflated with Artemis, according to an inscription from the late first century CE) was one of four sanctuaries built around Sparta in the Iron Age (1100-700 BCE). The sanctuary is located in the village of Limnai, and sits on a flat marshy hollow on the bank of the Eurotas River. The most conspicuous remains today are Roman, in particular an amphitheatre built in the third century CE, built around an earlier temple and altar dating to the sixth century BCE. The excavations in the early 1900s uncovered even earlier phases to this sanctuary, and recent reassessments of the excavation notebooks suggest the earliest structures may date back to the late ninth century BCE. The sanctuary became known from about the fourth century BCE onwards for the harsh rituals performed on the altar at this sanctuary. Both Plato (Laws) and Xenophon (Constitution of the Lacedaemonians) discuss the training Spartan youths received, enduring harsh trials as part of the system of education known as the agoge. The oft-cited flogging of Spartan youths on the altar of Orthia is mentioned Xenophon’s Constitution of the Lakedaimonians (2.8-9) and elaborated by later authors like Plutarch. Pausanias (3.16.7-11) ties the origins of these violent rites to early conflicts by members of the original four villages of Sparta, who fell to quarrelling and bloodshed over Orthia's altar. The excavations also uncovered a wide array of dedicated objects: ivory plaques and figurines dated primarily to the sixth century, later replaced by bone plaques and other ornaments (including votive flutes); a huge number of lead dedications, in particular lead figurines that reached the tens of thousands by the sixth and fifth centuries BCE; a corpus of clay masks dated to the sixth century representing various characters, including monsters and heroes; and other objects such as terracotta figurines and bronze figurines and jewelry.
title: Zirconia in protesi fissa: sistematiche comparate
title: Zirconia in fixed prothesis: systematic compared
titleType: AlternativeTitle
Creators: name: Bartolino, Martina
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: sistematica CAD/CAM; sistematiche comparate; ossido di zirconio
subject: sistematica CAD/CAM
subject: sistematiche comparate
subject: ossido di zirconio

description: 20. ciclo