cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(4282) John Scarlett Alexander Salt
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Canonical Kahler metrics and Arithmetics -- Generalising Faltings heights
Creators: name: Odaka, Yuji
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: Differential Geometry (math.DG)
subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We extend the Faltings modular heights of abelian varieties to general arithmetic varieties and show direct relations with the Kahler-Einstein geometry, the Minimal Model Program, heights of Bost and Zhang, and give some applications. Along the way, we propose arithmetic Yau-Tian-Donaldson conjecture, an equivalence of a purely arithmetic property of variety and its metrical property, and partially confirm it.
description: 47 pages. Final version, to appear in Kyoto Journal of Mathematics
Novel Insights into the Antimicrobial and Antibiofilm Activity of Pyrroloquinoline Quinone (PQQ); In Vitro, In Silico, and Shotgun Proteomic Studies
Creators: name: Labib, Mai M.
name: Alqahtani, Alaa
name: Abo Nahas, Hebatallah H.
name: Aldossari, Rana M.
name: Almiman, Bandar
name: Ayman Alnumaani, Sarah
name: Elnablaway, Mohammad
name: Al-Olayan, Ebtesam
name: Alsunbul, Maha
name: M. Saied, Essa
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: pyrroloquinoline quinone
subject: antimicrobial agents
subject: antibacterial activity
subject: antifungal activity
subject: MRSA
subject: antibiofilm activity
subject: TEM analysis
subject: shotgun proteomic analysis
subject: molecular modeling
subject: 570 Biologie

description: Microbial infections pose a significant global health threat, affecting millions of individuals and leading to substantial mortality rates. The increasing resistance of microorganisms to conventional treatments requires the development of novel antimicrobial agents. Pyrroloquinoline quinone (PQQ), a natural medicinal drug involved in various cellular processes, holds promise as a potential antimicrobial agent. In the present study, our aim was, for the first time, to explore the antimicrobial activity of PQQ against 29 pathogenic microbes, including 13 fungal strains, 8 Gram-positive bacteria, and 8 Gram-negative bacteria. Our findings revealed potent antifungal properties of PQQ, particularly against Syncephalastrum racemosum, Talaromyces marneffei, Candida lipolytica, and Trichophyton rubrum. The MIC values varied between fungal strains, and T. marneffei exhibited a lower MIC, indicating a greater susceptibility to PQQ. In addition, PQQ exhibited notable antibacterial activity against Gram-positive and -negative bacteria, with a prominent inhibition observed against Staphylococcus epidermidis, Proteus vulgaris, and MRSA strains. Remarkably, PQQ demonstrated considerable biofilm inhibition against the MRSA, S. epidermidis, and P. vulgaris strains. Transmission electron microscopy (TEM) studies revealed that PQQ caused structural damage and disrupted cell metabolism in bacterial cells, leading to aberrant morphology, compromised cell membrane integrity, and leakage of cytoplasmic contents. These findings were further affirmed by shotgun proteomic analysis, which revealed that PQQ targets several important cellular processes in bacteria, including membrane proteins, ATP metabolic processes, DNA repair processes, metal-binding proteins, and stress response. Finally, detailed molecular modeling investigations indicated that PQQ exhibits a substantial binding affinity score for key microbial targets, including the mannoprotein Mp1P, the transcriptional regulator TcaR, and the endonuclease PvuRTs1I. Taken together, our study underscores the effectiveness of PQQ as a broad-spectrum antimicrobial agent capable of combating pathogenic fungi and bacteria, while also inhibiting biofilm formation and targeting several critical biological processes, making it a promising therapeutic option for biofilm-related infections.
(4266) James Buchanan Seaton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
HOMO OECONOMICUS PERICULOSUS. MISURE DI PREVENZIONE E CRIMINALITA' DA PROFITTO, TRA ESIGENZE DI EFFETTIVITA' E CRISI DELLE GARANZIE
Creators: name: ZUFFADA, EDOARDO
Publisher: name: Universit� degli Studi di Milano
Year: 2020

description: Il lavoro di ricerca � dedicato allo studio delle misure di prevenzione ante delictum previste dal codice antimafia, sotto il particolare profilo della loro applicazione agli autori di reati economici. Con il presente studio si intende, da un lato, verificare se il suddetto orizzonte applicativo sia ad un tempo legittimo ed efficace e, dall?altro lato, se sia possibile percorrere il sentiero che conduce a un diverso e nuovo modello di controllo della pericolosit� in campo economico. Dopo aver ripercorso la ?storia? delle misure di prevenzione, la tesi di dottorato analizza criticamente la disciplina attualmente vigente delle misure di prevenzione personali e patrimoniali nei loro profili sostanziali e dedica ampio spazio allo studio dei decreti emessi dalla Sezione autonoma misure di prevenzione del Tribunale di Milano nei confronti di ?criminali economici? nel periodo compreso tra il 2015 e il 2019. Lo sguardo si allarga poi al diritto penale tradizionale, e vengono messe in luce le ?interferenze? del sistema di prevenzione con le altre misure che tradizionalmente svolgono una funzione specialpreventiva o una funzione ripristinatoria. Nel capitolo conclusivo, in una prospettiva de iure condendo, sono offerti alcuni spunti di riflessione per un sistema di prevenzione della criminalit� economica ?sostenibile?, che riesca a conciliare le esigenze di effettivit� con l?ineludibile tutela dei diritti fondamentali dei soggetti coinvolti.
Resonant Visible Light Modulation with Graphene
Creators: name: Yu, Renwen
name: Pruneri, Valerio
name: de Abajo, F. Javier Garcia
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Fast modulation and switching of light at visible and near-infrared (vis-NIR) frequencies is of utmost importance for optical signal processing and sensing technologies. No fundamental limit appears to prevent us from designing wavelength-sized devices capable of controlling the light phase and intensity at gigaherts (and even terahertz) speeds in those spectral ranges. However, this problem remains largely unsolved, despite recent advances in the use of quantum wells and phase-change materials for that purpose. Here, we explore an alternative solution based upon the remarkable electro-optical properties of graphene. In particular, we predict unity-order changes in the transmission and absorption of vis-NIR light produced upon electrical doping of graphene sheets coupled to realistically engineered optical cavities. The light intensity is enhanced at the graphene plane, and so is its absorption, which can be switched and modulated via Pauli blocking through varying the level of doping. Specifically, we explore dielectric planar cavities operating under either tunneling or Fabry-Perot resonant transmission conditions, as well as Mie modes in silicon nanospheres and lattice resonances in metal particle arrays. Our simulations reveal absolute variations in transmission exceeding 90% as well as an extinction ratio >15 dB with small insertion losses using feasible material parameters, thus supporting the application of graphene in fast electro-optics at vis-NIR frequencies.
description: 17 pages, 13 figures, 54 references
Fitting Skeletal Object Models Using Spherical Harmonics Based Template Warping
Creators: name: Yang, D.
name: Pizer, S.M.
name: Zhang, X.
name: Tu, L.
name: Vicory, J.
name: Styner, M.
Publisher: name: Institute of Electrical and Electronics Engineers Inc.
Year: 2015

description: We present a scheme that propagates a reference skeletal model (s-rep) into a particular case of an object, thereby propagating the initial shape-related layout of the skeleton-to-boundary vectors, called spokes. The scheme represents the surfaces of the template as well as the target objects by spherical harmonics and computes a warp between these via a thin plate spline. To form the propagated s-rep, it applies the warp to the spokes of the template s-rep and then statistically refines. This automatic approach promises to make s-rep fitting robust for complicated objects, which allows s-rep based statistics to be available to all. The improvement in fitting and statistics is significant compared with the previous methods and in statistics compared with a state-of-the-art boundary based method.
(4280) John Demain
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A Meta-graph Approach to Analyze Subgraph-centric Distributed Programming Models
Creators: name: Dindokar, Ravikant
name: Choudhury, Neel
name: Simmhan, Yogesh
Publisher: name: arXiv
Year: 2015
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Component-centric distributed graph processing platforms that use a bulk synchronous parallel (BSP) programming model have gained traction. These address the short-comings of Big Data abstractions/platforms like MapReduce/Hadoop for large-scale graph processing. However, there is limited literature on foundational aspects of the behavior of these component-centric abstractions for different graphs, graph partitioning, and graph algorithms. Here, we propose a analytical approach based on a meta-graph sketch to examine the characteristics of component-centric graph programming models at a coarse granularity. In particular, we apply this sketch to subgraph- and block-centric abstractions, and draw a comparison with vertex-centric models like Google's Pregel. First, we explore the impact of various graph partitioning techniques on the meta-graph, and next consider the impact of the meta-graph on graph algorithms. This decouples the unwieldy large graph and their partitioning specific artifacts from their algorithmic analysis. We use 5 spatial and powerlaw graphs as exemplars, four different partitioning strategies, and PageRank and Breadth First Search as canonical algorithms. These analysis over the meta-graphs provide a reliable measure of the expected number of supersteps, and the communication and computational complexity of the algorithms for various graphs, and the relative merits of subgraph-centric models over vertex-centric ones.
Progress towards quantum-enhanced interferometry with harmonically trapped quantum matter-wave bright solitons
Creators: name: Gertjerenken, Bettina
name: Wiles, Timothy P.
name: Weiss, Christoph
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We model the dynamics of attractively interacting ultracold bosonic atoms in a quasi-one-dimensional wave-guide with additional harmonic trapping. Initially, we prepare the system in its ground state and then shift the zero of the harmonic trap and switch on an additional narrow scattering potential near the center of the trap. After colliding with the barrier twice, we propose to measure the number of atoms opposite to the initial condition. Quantum-enhanced interferometry with quantum bright solitons allows us to predict detection of an offset of the scattering potential with considerably increased precision as compared to single-particle experiments. In a future experimental realization this might lead to measurement of weak forces caused, for example, by small horizontal gradients in the gravitational potential - with a resolution of several micrometers given essentially by the size of the solitons. Our numerical simulations are based on the rigorously proved effective potential approach developed in [Phys. Rev. Lett. 102, 010403 (2009) and Phys. Rev. Lett. 103, 210402 (2009)]. We choose our parameters such that the prerequisite of the proof (that the solitons cannot break apart, for energetic reasons) is always fulfilled, thus exploring a parameter regime inaccessible to the mean-field description via the Gross-Pitaevskii equation due to Schrodinger-cat states occurring in the many-particle quantum dynamics.
description: 10 pages, 3 figures, minor revisions
Determinants of Banking Sector Development in Ethiopia
Creators: name: Abreha Gezae
Publisher: name: Zenodo
Year: 2015

description: The study focuses on the investigation of the macro factors that affect the development of the banking sector. Because the banking sector is rudimentary due to the problems such as heavy dependence of investors in borrowed fund, excessive government borrowing, absence of secondary markets, less attractive deposit rate, limited outreach of banking services, underdeveloped saving culture, poor cross-selling activity of inflow of foreign remittance, deficit in the trade balance of the country. The purpose of this study is, therefore, to investigate the significant determinants and recommend courses of action to be taken and analyse the level of development in comparison to other East African countries. Quantitative research approach is applied using econometric model estimated OLS multiple linear regression and descriptive quantitative analysis technique. The study has found that Trade Openness, Real Interest rate, population growth, and Government consumption expenditure have far reached statistically significant impact on the development of the banking sector by influencing the volume of credit provided by banks to the private sector. Remittance to GDP ratio, Real Interest Rate and GDP growth rate significantly impact the broad money supply (M2).
A SPINE TO NUCLEUS SIGNALING PATHWAY IN ALZHEIMER�S DISEASE
Creators: name: DA ROCHA RIBEIRO, ANA CLAUDIA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: Ring Finger Protein 10 (RNF10) � una proteina messaggero sinaptonucleare localizzata a livello delle sinapsi eccitatorie e associata con la subunit� GluN2A del recettore NMDA. Stimolazione dei recettori NMDA contenenti la subunit� GluN2A induce il trasporto di RNF10 dalla sinapsi al nucleo e la conseguente espressione di specifici geni bersaglio, alcuni dei quali svolgono un ruolo nella patogenesi della malattia di Alzheimer o nella modulazione della morfologia delle spine dendritiche. E? inoltre importante osservare come l?espressione di RNF10 sia ridotta negli ippocampi di pazienti con malattia di Alzheimer e come oligomeri di A? siano in grado di indurre il trasporto di RNF10 dalla sinapsi al nucleo. Il principale obiettivo del progetto di dottorato � la caratterizzazione del ruolo di RNF10 nei processi cognitivi e la plasticit� sinaptica utilizzando gli animali RNF10 KO quale modello sperimentale. I topi RNF10 KO sono caratterizzati da una riduzione del peso corporeo e da un concomitante aumento dell?assunzione di cibo in assenza di modificazioni significative dei livelli di glucosio, insulina e FGF-21. L?analisi molecolare ha mostrato una riduzione nell?animale RNF10 delle proteine coinvolte nel metabolismo di APP nell?ippocampo e una conseguente riduzione dei livelli di A?. L?analisi morfologica ha mostrato un aumento significativo delle spine dendritiche mushroom e una concomitante riduzione delle spine sottili. Una approfondita analisi del comportamento ha rilevato come gli animali RNF10 KO non presentino modificazioni del comportamento motorio, sia in animali adulti che anziani, mentre � stata osservata una moderata alterata alterazione sia dell?esplorazione che della memoria a lungo termine. Inoltre, gli animali RNF10 sono caratterizzati dalla completa assenza di potenziamento a lungo termine nell?area CA1 dell?ippocampo. In conclusione, questi risultati suggeriscono il coinvolgimento di RNF10 nella patogenesi della malattia di Alzheimer e indicano un possibile ruolo di questa proteina nelle alterazioni delle capacit� cognitive associate all?invecchiamento.
(4263) Philip Simpson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Technoculture and its Lived Consequences
title: A Terminal Marketing Approach
titleType: Subtitle
Creators: name: Hoang Ngoc, Quynh
Publisher: name: Lancaster University
Year: 2023
Subjects: TECHNOLOGY
consumer culture theory

description: This thesis is situated within an ultra-realist vein of marketing scholarship – what has recently been called “Terminal Marketing” or “de-romanticist consumer research” – that seeks to countervail utopian assumptions of an all-empowered consumer subject. Focusing on the intersection of technology with consumer culture (i.e., “technoculture”) as an empirical context, this thesis introduces novel conceptualisations of consumer subjectivity, its disempowerment and depoliticisation. Combining the cultural theories of Mark Fisher, Slavoj Žižek, and Steve Redhead with empirical fieldwork involving a 12-month netnography and 21 in-depth interviews with those who seek to unplug themselves from technoculture (i.e., “digital detoxers”), the entrapment and foreclosure that frames technoculture and its subjectivities is conceptualised. Emergent findings are organised into three research chapters (one theoretical and two empirical manuscripts). Altogether, these chapters map out a dystopian, “terminal” stage of consumer capitalism populated by increasingly disenchanted and knowingly helpless subjects whose pro- and anti-market behaviours are barely distinguishable in terms of genuine autonomy or transformative power. In tracing the various contours of consumers’ inertia and bleak dissatisfactions with their everyday digital lives, the findings reveal an increasingly unbearable onto-affective atmosphere of inescapability that cannot be discharged in any meaningful way. In the absence of collective hope for genuine alternatives to the existing system, consumers are resigned to accept the perceived unchangeability of the structural conditions that perpetuate their attachment to market-mediated fantasies and market-located solutions. The thesis explores the consequences of living within what Terminal Marketing scholarship classifies as a state of “cancelled futures” under capitalism.
Quantum efficiencies in finite disordered networks connected by many-body interactions
Creators: name: Ortega, Adrian
name: Vyas, Manan
name: Benet, Luis
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The quantum efficiency in the transfer of an initial excitation in disordered finite networks, modeled by the $k$-body embedded Gaussian ensembles of random matrices, is studied for bosons and fermions. The influence of the presence or absence of time-reversal symmetry and centrosymmetry/centrohermiticity are addressed. For bosons and fermions, the best efficiencies of the realizations of the ensemble are dramatically enhanced when centrosymmetry (centrohermiticity) is imposed. For few bosons distributed in two single-particle levels this permits perfect state transfer for almost all realizations when one-particle interactions are considered. For fermionic systems the enhancement is found to be maximal for cases when all but one single particle levels are occupied.
description: 9 pages, 4 figures, submitted to Annalen der Physik
(4264) William Moore Crosthwaite
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Quantitative tract-based white matter heritability in twin neonates
Creators: name: Gilmore, J.H.
name: Steiner, R.J.
name: Neale, M.C.
name: Zhu, H.
name: Lee, S.J.
name: Styner, M.
name: Luo, S.
Publisher: name: Academic Press Inc.
Year: 2015

description: Studies in adults indicate that white matter microstructure, assessed with diffusion tensor imaging (DTI), has high heritability. Little is known about genetic and environmental influences on DTI parameters, measured along fiber tracts particularly, in early childhood. In the present study, we report comprehensive heritability data of white matter microstructure fractional anisotropy (FA), radial diffusion (RD), and axial diffusion (AD) along 47 fiber tracts using the quantitative tractography in a large sample of neonatal twins (n. =. 356). We found significant genetic influences in almost all tracts with similar heritabilities for FA, RD, and AD as well as positive relationships between these parameters and heritability. In a single tract analysis, genetic influences along the length of the tract were highly variable. These findings suggest that at birth, there is marked heterogeneity of genetic influences of white matter microstructure within white matter tracts. This study provides a basis for future studies of developmental changes in genetic and environmental influences during early childhood, a period of rapid development that likely plays a major role in individual differences in white matter structure and function.
A THESIS SUBMITTED TO THE DEPARTMENT OF HEMATOLOGY & IMMUNOHEMATOLOGY, SCHOOL OF BIOMEDICAL AND LABORATORY SCIENCES, COLLEGE OF MEDICINE AND HEALTH SCIENCES, UNIVERSITY OF GONDAR FOR THE PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE IN HEMATOLOGY
Creators: name: Yitayal Amogne
Publisher: name: Zenodo
Year: 2015

description: Introduction: Diabetes mellitus is a metabolic disorder characterized with chronic hyperglycemia which results in polyuria, polydipsia and polyphagia. The incidence of cardiovascular disease (CVD) due to thrombosis is 2-4 folds greater in diabetic patients than the general population. Prothrombine time, activated partial thromboplastin time and platelet count are hematological indices that give an insight about the coagulation status of diabetic mellitus patients.

Objective: -To compare Prothrombin time, activated partial thromboplastin time and platelet count of type II diabetes mellitus patients attending Felegehiwot referral hospital, Bahir Dar, Northwest Ethiopia.

Method: A comparative cross-sectional study from March to April 2015 was carried out on a total of 40 treated type II diabetic, 40 untreated diabetics and 40 non-diabetic controls with similar age range of 30-60years.Simple random sampling technique was used to select study subjects of untreated DM and systematic sampling technique was used to select study subjects of both treated type II DM and non-diabetic individuals. Demographic data were collected through face to face interview and about 4ml of blood was collected aseptically by Felegehiwot referral hospital laboratory staff. The collected data was entered and analyzed through SPSS ver 16.One-way Anova and independent t-test were used to compare means of PT, aPTT and platelet count. P <0.05 was considered as statically significant
(4269) Samuel Crawford
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
ESTUDO DO AGENTE CHLAMYDOPHILA PSITTACI POR PCR EM CALOPSITA NYMPHICUS HOLLANDICUS
Creators: name: Bonorino, Rafael Prange
name: Andryelle Assunção Fraga
Publisher: name: figshare
Year: 2020
Subjects: subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: A Chamydophila psttaci é uma bactéria gram. negativa intracelular obrigatória, conhecida popularmente como clamidiose aviária. Acomete aves e mamíferos, incluindo o ser humano causando sinais clínicos sintomáticos. Essa patologia é uma das principais zoonoses acometidas por aves que preocupa a saúde humana. Foi realizada uma pesquisa para saber a incidência da doença nas Agropecuárias do DF. Várias porções de fezes espalhadas pela gaiola foram recolhidas para realizar exames de fezes por PCR para detecção de C. psittaci em calopsitas. Foram coletadas 32 amostras aleatórias de fezes em diferentes agropecuárias no DF. Os proprietários autorizaram as coletas diretamente das gaiolas sem a necessidade de contenção das aves para a relevância da pesquisa e autorizaram as coletas, as quais foram divididas em três lotes. Cada gaiola havia aproximadamente 10 animais. Os materiais foram armazenados em frascos com solução conservativa e devidamente rotulados com a identificação do local, após enviados para o laboratório de referência para análise. Os Testes utilizando PCR para detecção de C. psittaci possuem o valor de gene mpA. As fezes foram coletadas diretamente das gaiolas onde havia uma bandeja para deposito dos mesmos sem necessidade de contenção da ave. Concluiu-se que não houve incidência do agente em Agropecuárias do DF no período pesquisado, porém não se descarta que devemos ficar atento à doença, pois uma vez ela sendo encontrada no ambiente, as aves podem ser assintomáticas e consequentemente afetar os seres humanos.
Neutrino Physics
Creators: name: Barenboim, G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Standard Model has been incredibly successful in predicting the outcome of almost all the experiments done up so far. In it, neutrinos are mass-less. However, in recent years we have accumulated evidence pointing to tiny masses for the neutrinos (as compared to the charged leptons). These masses allow neutrinos to change their flavour and oscillate. In these lectures I review the properties of neutrinos in and beyond the Standard Model.
description: 19 pages, contribution to the 2012 European School of High-Energy Physics, La Pommeraye, Anjou, France, 06-19 Jun 2012, edited by C. Grojean and M. Mulders. arXiv admin note: text overlap with arXiv:hep-ph/0506165 by other authors
(4262) Crosthwaite
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Early adverse experience increases emotional reactivity in juvenile rhesus macaques: Relation to amygdala volume
Creators: name: Grand, A.P.
name: Laprarie, J.L.
name: Maestripieri, D.
name: Styner, M.A.
name: Mccormack, K.M.
name: Sanchez, M.M.
name: Shi, Y.
name: Howell, B.R.
Publisher: name: John Wiley and Sons Inc.
Year: 2014

description: This study investigated the impact of infant maltreatment on juvenile rhesus monkeys' behavioral reactivity to novel stimuli and its associations with amygdala volume. Behavioral reactivity to novel stimuli of varying threat intensity was measured using Approach/Avoidance (AA) and Human Intruder (HI) tasks. In vivo magnetic resonance imaging (MRI) was used to measure amygdala volume. Interestingly, group behavioral differences were context-dependent. When exposed to a human intruder, maltreated subjects displayed more anxious behaviors than controls; however, when presented with fear-evoking objects, maltreated animals exhibited increased aggression and a shorter latency to inspect the objects. Finally, under testing conditions with the lowest levels of threat (neutral novel objects) maltreated animals also showed shorter latencies to inspect objects, and reduced avoidance and increased exploration compared to controls. This suggests alterations in threat assessment and less behavioral inhibition in animals with early adverse experience compared to controls. Some of these behavioral responses were associated with amygdala volume, which was positively correlated with abuse rates received during infancy, particularly reflecting a relationship with exploration, consistent with previous studies.
Automated voxel-wise brain DTI analysis of fitness and aging
Creators: name: Goodlett, C.B.
name: Farzinfar, M.
name: Marks, B.L.
name: Zhu, H.
name: Gerig, G.
name: Katz, L.M.
name: Styner, M.
name: Liu, Z.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Diffusion Tensor Imaging (DTI) has become a widely used MR modality to investigate white matter integrity in the brain. This paper presents the application of an automated method for voxel-wise group comparisons of DTI images in a study of fitness and aging. The automated processing method consists of 3 steps: 1) preprocessing including image format converting, image quality control, eddy-current and motion artifact correction, skull stripping and tensor image estimation, 2) study-specific unbiased DTI atlas computation via diffeomorphic fluid-based and demons deformable registration and 3) voxel-wise statistical analysis via heterogeneous linear regression and a wild bootstrap technique for correcting for multiple comparisons. Our results show that this fully automated method is suitable for voxel-wise group DTI analysis. Furthermore, in older adults, the results suggest a strong link between reduced fractional anisotropy (FA) values, fitness and aging.
Dark Matter and Global Symmetries
Creators: name: Mambrini, Yann
name: Profumo, Stefano
name: Queiroz, Farinaldo S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: General considerations in general relativity and quantum mechanics are known to potentially rule out continuous global symmetries in the context of any consistent theory of quantum gravity. Assuming the validity of such considerations, we derive stringent bounds from gamma-ray, X-ray, cosmic-ray, neutrino, and CMB data on models that invoke global symmetries to stabilize the dark matter particle. We compute up-to-date, robust model-independent limits on the dark matter lifetime for a variety of Planck-scale suppressed dimension-five effective operators. We then specialize our analysis and apply our bounds to specific models including the Two-Higgs-Doublet, Left-Right, Singlet Fermionic, Zee-Babu, 3-3-1 and Radiative See-Saw models. {Assuming that (i) global symmetries are broken at the Planck scale, that (ii) the non-renormalizable operators mediating dark matter decay have $O(1)$ couplings, that (iii) the dark matter is a singlet field, and that (iv) the dark matter density distribution is well described by a NFW profile}, we are able to rule out fermionic, vector, and scalar dark matter candidates across a broad mass range (keV-TeV), including the WIMP regime.
description: Matches Published version in Phys.Lett. B760 (2016) 807-815
Designing the Ion Gate of a Time-of-Flight Mass Spectrometer
Creators: name: Furman, Adam Mark
Publisher: name: Zenodo
Year: 2022
Subjects: physics
mass spectrometry
time of flight
protein
simulation

description: The Stein lab is developing a time-of-flight mass spectrometer (TOF-MS) to determine whether a nanopore ion source can emit amino acids directly into high vacuum without also producing charged droplets. A crucial component of the spectrometer is the ion gate, which blocks the flow of ions into the spectrometer’s flight chamber until the measurement begins. This thesis describes the design of the ion gate. First, a simulation framework is created to model how two proposed gate designs interact with ions. The simulation framework is tested to ensure its physical accuracy, and then is used to determine the minimum voltage necessary to open and close the ion gate. A parallel plate deflection-based gate design is chosen because it requires less voltage to operate than a mesh-based design. Calculations are carried out to determine the gate’s impact on the accuracy of the mass spectrometer, and the impact is found to be minimal based on both the size of the gate and its electrical properties. The gate is designed was created in 3D modelling software and fabricated by a machine shop. The gate is then cleaned and mounted onto the assembly of the mass spectrometer. Experimental data shows that the gate functions as expected, and that the voltage required to operate it conforms to the results of the simulations.
How do men who are unknown to authorities for using violence and abuse towards women experience their actions?
Creators: name: Sparkes, Deborah
Publisher: name: Anglia Ruskin Research Online (ARRO)
Year: 2024

description: This research is sited within the area of Domestic Violence and Abuse (DVA), a complex, enduring and multifaceted global issue. Whilst acknowledging DVA affects men and women this research considers men’s violence and abuse towards intimate partner women. In highlighting a current paucity of research with men who use DVA this research offers an original contribution to knowledge through a focus on understanding more from men who are unknown to authorities about how they experience their violent and abusive actions.Existing research with men often repetitiously focuses on description of incidents and is mostly gained from men enrolled on some form of domestic violence and abuse perpetrator programme. This qualitative research reports on the findings from interviews held with eight men who self-identified as using DVA and who had no authority involvement related to their DVA actions.Whilst there is evidence in the findings of denial, minimising and blaming others, which is a theme of existing research, participants were also able to reflect earnestly on how they thought and felt about their actions. Additionally, the findings offer further understanding of how participants have avoided being reported for DVA even though in a majority of cases somebody else outside of the couple relationship knew about their violence and abuse.Men who are unknown to authorities are willing to be part of DVA research. Some of the findings echo earlier research but there are poignant reflections from participants on how DVA has remained unadjudicated and the circumstances in which they have spoken to others about their actions. It is clear from participant accounts that DVA was not a positive experience for them either. Men who use DVA are responsible for their own actions but there is a role for family, friends and society in supporting attitudinal shift so that stigma and taboo surrounding DVA is not a barrier to accountability or for men who want to seek help to change. There are important implications for policy and practice for the multiple agencies working with DVA to gain a better understanding of men’s experiences.
Generation of 1.5-octave intense infrared pulses by nonlinear interactions in DAST crystal
Creators: name: Vicario, Carlo
name: Monoszlai, Balazs
name: Arisholm, Gunnar
name: Hauri, Christoph P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Infrared pulses with large spectral width extending from 1.2 to 3.4 um are generated in the organic crystal DAST (4-N, N-dimethylamino-4-N-methylstilbazolium tosylate). The input pulse has a central wavelength of 1.5 um and 65 fs duration. With 2.8 mJ input energy we obtained up to 700 uJ in the broadened spectrum. The output can be easily scaled up in energy by increasing the crystal size together with the energy and the beam size of the pump. The ultra-broad spectrum is ascribed to cascaded second order processes mediated by the exceptionally large effective chi2 nonlinearity of DAST, but the shape of the spectrum indicates that a delayed chi3 process may also be involved. Numerical simulations reproduce the experimental results qualitatively and provide an insight in the mechanisms underlying the asymmetric spectral broadening.
The Paradox of Muscle Hypertrophy in Muscular Dystrophy
Creators: name: Schatzberg, S.J.
name: Childers, M.K.
name: Howard Jr., J.F.
name: Grange, R.W.
name: Nghiem, P.
name: Wagner, K.R.
name: Wang, J.
name: Hoffman, E.P.
name: Kornegay, J.N.
name: Fan, Z.
name: Bogan, D.J.
name: Dow, J.L.
name: Styner, M.A.
name: Bogan, J.R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Mutations in the dystrophin gene cause Duchenne and Becker muscular dystrophy in humans and syndromes in mice, dogs, and cats. Affected humans and dogs have progressive disease that leads primarily to muscle atrophy. Mdx mice progress through an initial phase of muscle hypertrophy followed by atrophy. Cats have persistent muscle hypertrophy. Hypertrophy in humans has been attributed to deposition of fat and connective tissue (pseudohypertrophy). Increased muscle mass (true hypertrophy) has been documented in animal models. Muscle hypertrophy can exaggerate postural instability and joint contractures. Deleterious consequences of muscle hypertrophy should be considered when developing treatments for muscular dystrophy.
title: Self-serving Bias in Redistribution Choices: Accounting for Beliefs and Norms
Creators: name: Amasino, Dianna
name: Pace, Davide Domenico
name: Weele, Joel van der
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2023

description: People with higher-incomes tend to support less redistribution than lower-income people. This has been attributed not only to self-interest, but also to psychological mechanisms including differing beliefs about the hard work or luck underlying inequality, differing fairness views, and differing perceptions of social norms. In this study, we directly measure each of these mechanisms and compare their mediating roles in the relationship between status and redistribution. In our experiment, participants complete real-effort tasks and then are randomly assigned a high or low pay rate per correct answer to exogenously induce (dis)advantaged status. Participants are then paired and those assigned the role of dictator decide how to divide their joint earnings. We find that advantaged dictators keep more for themselves than disadvantaged dictators and report different fairness views and beliefs about task performance, but not different beliefs about social norms. Further, only fairness views play a significant mediating role between status and allocation differences, suggesting this is the primary mechanism underlying self-serving differences in support for redistribution.
Use of high resolution 3D diffusion tensor imaging to study brain white matter development in live neonatal rats
Creators: name: Johns, J.M.
name: Oguz, I.
name: McMurray, M.S.
name: Styner, M.A.
name: An, H.
name: Lin, W.
name: Cai, Y.
name: Yuan, H.
Publisher: name: Frontiers Media S.A.
Year: 2011

description: High resolution diffusion tensor imaging (DTI) can provide important information on brain development, yet it is challenging in live neonatal rats due to the small size of neonatal brain and motion-sensitive nature of DTI. Imaging in live neonatal rats has clear advantages over fixed brain scans, as longitudinal and functional studies would be feasible to understand neuro-developmental abnormalities. In this study, we developed imaging strategies that can be used to obtain high resolution 3D DTI images in live neonatal rats at postnatal day 5 (PND5) and PND14, using only 3 h of imaging acquisition time. An optimized 3D DTI pulse sequence and appropriate animal setup to minimize physiological motion artifacts are the keys to successful high resolution 3D DTI imaging. Thus, a 3D rapid acquisition relaxation enhancement DTI sequence with twin navigator echoes was implemented to accelerate imaging acquisition time and minimize motion artifacts. It has been suggested that neonatal mammals possess a unique ability to tolerate mild-to-moderate hypothermia and hypoxia without long term impact. Thus, we additionally utilized this ability to minimize motion artifacts in magnetic resonance images by carefully suppressing the respiratory rate to around 15/min for PND5 and 30/min for PND14 using mild-to-moderate hypothermia. These imaging strategies have been successfully implemented to study how the effect of cocaine exposure in dams might affect brain development in their rat pups. Image quality resulting from this in vivo DTI study was comparable to ex vivo scans. fractional anisotropy values were also similar between the live and fixed brain scans. The capability of acquiring high quality in vivo DTI imaging offers a valuable opportunity to study many neurological disorders in brain development in an authentic living environment.
The Luminosity of Population III Star Clusters
Creators: name: DeSouza, Alexander L.
name: Basu, Shantanu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We analyze the time evolution of the luminosity of a cluster of Population III protostars formed in the early universe. We argue from the Jeans criterion that primordial gas can collapse to form a cluster of first stars that evolve relatively independently of one another (i.e., with negligible gravitational interaction). We model the collapse of individual protostellar clumps using 2+1D nonaxisymmetric numerical hydrodynamics simulations. Each collapse produces a protostar surrounded by a massive disk (i.e., $M_{\rm disk} / M_{*} \gtrsim 0.1$), whose evolution we follow for a further 30--40 kyr. Gravitational instabilities result in the fragmentation and the formation of gravitationally bound clumps within the disk. The accretion of these fragments by the host protostar produces accretion and luminosity bursts on the order of $10^6\,\LSun$. Within the cluster, we show that a simultaneity of such events across several protostellar cluster members can elevate the cluster luminosity to 5--10${\times}$ greater than expected, and that the cluster spends $\sim15\%$ of it's star-forming history at these levels. This enhanced luminosity effect is particularly enabled in clusters of modest size with $\simeq$ 10--20 members. In one such instance, we identify a confluence of burst events that raise the luminosity to nearly $1000{\times}$ greater than the cluster mean luminosity, resulting in $L > 10^8\,\LSun$. This phenomenon arises solely through the gravitational-instability--driven episodic fragmentation and accretion that characterizes this early stage of protostellar evolution.
description: 10 pages, 7 figures, to appear in MNRAS