cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Deliverable 6.21 Sea ice and snow thickness from SIMBA buoy experiments
Creators: name: Cheng, Bin
name: Lei, Ruibo
name: Tian, Zhongxiang
name: Pirazzini, Roberta
Publisher: name: Zenodo
Year: 2021
Subjects: Arctic
INTAROS
Ocean Observing Systems
Sea Ice Observing Systems
In Situ Data
Snow
Mass Balance

description: Snow depth and ice thickness in the Arctic Ocean directly result from air-sea ice-ocean interaction and their observational data are essential components of the iAOS. During INTAROS, an innovative and cost-cutting design, thermistor string-based snow and ice mass balance apparatus (SIMBA), has been largely deployed in the Arctic Ocean to measure time series of high-resolution vertical temperature profiles through air-snow-sea ice-ocean, and snow depth and ice thickness are derived from SIMBA temperatures. This document summarizes the SIMBA deployment during the INTAROS period. The SIMBA data characteristics and how to derive snow depth and ice thickness from temperature are described. The results from manual analyses and automatic algorithms are compared to each other. We have summarized a few process studies using SIMBA data. The data provided by SIMBA experiments are not only valuable for remote sensing applications but also important to better understand air-sea ice-ocean interactions as well as for process modelling studies. The accessibility to data and repositories of SIMBA data is concluded. The further exploitation of SIMBA observation as well as how it can possibly be used as a component of the sustainable iAOS are discussed. The document is intended to provide a summary of SIMBA operation in the high-Arctic regions and how the SIMBA data can be used for scientific research and for future operation service and sea ice management.
Regularity and Planarity of Token Graphs
Creators: name: Carballosa, Walter
name: Fabila-Monroy, Ruy
name: Leaños, Jesús
name: Rivera, Luis Manuel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C10, 05C69

description: Let $G=(V,E)$ be a graph of order $n$ and let $1\leq k< n$ be an integer. The $k$-token graph of $G$ is the graph whose vertices are all the $k$-subsets of $V$, two of which are adjacent whenever their symmetric difference is a pair of adjacent vertices in $G$. In this paper we characterize precisely, for each value of $k$, which graphs have a regular $k$-token graph and which connected graphs have a planar $k$-token graph.
description: 13 pages, 5 figures. Referee suggestions and corrections incorporated (in particular, a mistake in the proof of Theorem 2.9 was fixed). One reference added. Accepted for publication in "Discussiones Mathematicae Graph Theory"
Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies
Creators: name: Vliet, Kim Van
name: Agbandje-McKenna, Mavis
name: Byrne, Barry J.
name: Rao, Lavanya
name: Tseng, Yu-Shan
name: Asokan, Aravind
name: McKenna, Robert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Adeno-associated viruses (AAVs) are promising viral vectors for therapeutic gene delivery, and the approval of an AAV1 vector for the treatment of lipoprotein lipase deficiency has heralded a new and exciting era for this system. However, preclinical and clinical studies show that neutralization from pre-existing antibodies is detrimental for medical application and this hurdle must be overcome before full clinical realization can be achieved. Thus the binding sites for capsid antibodies must be identified and eliminated through capsid engineering. Towards this goal and to recapitulate patient polyclonal responses, a panel of eight new mouse monoclonal antibodies (MAbs) has been generated against AAV8 and AAV9 capsids, two vectors in development for therapeutic application. Native (capsid) dot blot assays confirmed the specificity of these antibodies for their parental serotypes, with the exception of one MAb, HL2372, selected to cross-react against both capsids. Furthermore, in vitro assays showed that these MAbs are capable of neutralizing virus infection. These MAbs will be utilized for structural mapping of antigenic footprints on their respective capsids to inform development of the next generation of rAAV vectors capable of evading antibody neutralization while retaining parental tropism.
Additional file 1 of “If the social circle is engaged, more pregnant women will successfully quit smoking”: a qualitative study of the experiences of midwives in the Netherlands with smoking cessation care
Creators: name: Willemse, Eefje
name: Walters, Bethany Hipple
name: Springvloet, Linda
name: Bommelé, Jeroen
name: Willemsen, Marc C.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1. Interview guide for birth care providers.
Vorstellung Zwischenergebnisse - Hochschulen als Akteure im Dialog mit China
Creators: name: Stepan, Matthias
Publisher: name: Zenodo
Year: 2023
Subjects: China
Higher Education
Germany
Research
Cooperation

description: Zwischenergebnisse des Forschungsprojekts "Hochschulen als Akteure im Dialog mit China" wurden im September 2022 im Rahmen eines akademischen Workshops an der Ruhr-Universität Bochum vorgestellt.
description: The workshop was an output of the research project "Hochschulen als Akteure im Dialog mit China" funded by Stiftung Mercator.
Electric dipole moment of $^{225}$Ra due to P- and T-violating weak interactions
Creators: name: Singh, Yashpal
name: Sahoo, B. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We report rigorous calculations of electric dipole moment (EDM) in $^{225}$Ra due to parity and time-reversal violating tensor-pseudotensor (T-PT) and nuclear Schiff moment (NSM) interactions between the electrons and nucleus by employing the relativistic all order coupled-cluster (RCC) methods at various levels of approximation. The most accurate EDM ($d_A$) results are obtained as $d_A=-10.04\times 10^{-20} C_T |e|cm$ and $d_A^{NSM}=-6.79 \times 10^{-17} S (|e|fm^3)^{-1} |e|cm$ with $C_T$ and $S$ are the T-PT coupling constant and NSM respectively. Due to exhaustive treatment of the electron correlation effects in these calculations, the EDM results for the corresponding T-PT and NSM interactions reduce by about 45\% and 23\%, respectively, from the previously known values. Nonetheless they are still found to be 2-3 times larger than the $^{199}$Hg results. Validity of the RCC results are countenanced by comparing our calculations at the zeroth order Dirac-Fock method and all order random-phase approximation with the other groups. In view of the current experimental progress in the $^{225}$Ra EDM measurement, our high accuracy calculations are very useful to yield limits on $C_T$ and $S$ in this atom. Thusly, it is possible to realize more accurate limits on the electron-quark T-PT interaction and $θ_{QCD}$ parameter of particle physics in future.
description: 5 pages, 1 figure and 2 tables. Comments and suggestions are welcome
Selaginella popayanensis Hieron., Hedwigia
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Lycopodiopsida
Selaginellales
Selaginellaceae
Selaginella
Selaginella popayanensis

description: Selaginella popayanensis Hieron., Hedwigia 43: 9. 1904.
 Range: —Disjunct in mountains of southern Mexico and Guatemala; Costa Rica and Panama; Venezuela and Colombia; Bolivia (CO, LP, SC).
 Ecology: —Uncommon; terrestrial in humid forests, usually on wet mossy rocks; 1100–3100 m.
 Notes: —The diagnostic hairs on the adaxial leaf surfaces are usually visible only through a good dissecting microscope, ideally with oblique light so that the hairs cast shadows. A variable species that may comprise several taxa.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. III. Selaginellaceae, pp. 248-258 in Phytotaxa 344 (3) on page 255, DOI: 10.11646/phytotaxa.344.3.5, http://zenodo.org/record/13719508
A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton Rats
Creators: name: Pickles, Ray J.
name: Gilbert, Brian E.
name: Stobart, Christopher C.
name: Piedra, Pedro A.
name: Blanco, Jorge C.G.
name: Graham, Barney S.
name: Moore, Martin L.
name: Hotard, Anne L.
name: Moin, Syed M.
name: Rostad, Christina A.
name: Meng, Jia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: ABSTRACT Although respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in infants, a safe and effective vaccine is not yet available. Live-attenuated vaccines (LAVs) are the most advanced vaccine candidates in RSV-naive infants. However, designing an LAV with appropriate attenuation yet sufficient immunogenicity has proven challenging. In this study, we implemented reverse genetics to address these obstacles with a multifaceted LAV design that combined the codon deoptimization of genes for nonstructural proteins NS1 and NS2 (dNS), deletion of the small hydrophobic protein (ΔSH) gene, and replacement of the wild-type fusion (F) protein gene with a low-fusion RSV subgroup B F consensus sequence of the Buenos Aires clade (BAF). This vaccine candidate, RSV-A2-dNS-ΔSH-BAF (DB1), was attenuated in two models of primary human airway epithelial cells and in the upper and lower airways of cotton rats. DB1 was also highly immunogenic in cotton rats and elicited broadly neutralizing antibodies against a diverse panel of recombinant RSV strains. When vaccinated cotton rats were challenged with wild-type RSV A, DB1 reduced viral titers in the upper and lower airways by 3.8 log 10 total PFU and 2.7 log 10 PFU/g of tissue, respectively, compared to those in unvaccinated animals ( P < 0.0001). DB1 was thus attenuated, highly immunogenic, and protective against RSV challenge in cotton rats. DB1 is the first RSV LAV to incorporate a low-fusion F protein as a strategy to attenuate viral replication and preserve immunogenicity. IMPORTANCE RSV is a leading cause of infant hospitalizations and deaths. The development of an effective vaccine for this high-risk population is therefore a public health priority. Although live-attenuated vaccines have been safely administered to RSV-naive infants, strategies to balance vaccine attenuation with immunogenicity have been elusive. In this study, we introduced a novel strategy to attenuate a recombinant RSV vaccine by incorporating a low-fusion, subgroup B F protein in the genetic background of codon-deoptimized nonstructural protein genes and a deleted small hydrophobic protein gene. The resultant vaccine candidate, DB1, was attenuated, highly immunogenic, and protective against RSV challenge in cotton rats.
Exotica ex nihilo: Traversable wormholes & non-singular black holes from the vacuum of quadratic gravity
Creators: name: Duplessis, Francis
name: Easson, Damien A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present new traversable wormhole and non-singular black hole solutions in pure, scale-free $R^2$ gravity. These exotic solutions require no null energy condition violating or "exotic" matter and are supported only by the vacuum of the theory. It is well known that $f(R)$ theories of gravity may be recast as dual theories in the Einstein frame. The solutions we present are found when the conformal transformation required to move to the dual frame is singular. For quadratic $R^2$ gravity, the required conformal factor is identically zero for spacetimes with $R=0$. Solutions in this case are argued to arise in the strong coupling limit of General Relativity.
description: Minor revisions, version to appear in PRD, 8 pages, 3 figures
Additional file 2 of “If the social circle is engaged, more pregnant women will successfully quit smoking”: a qualitative study of the experiences of midwives in the Netherlands with smoking cessation care
Creators: name: Willemse, Eefje
name: Walters, Bethany Hipple
name: Springvloet, Linda
name: Bommelé, Jeroen
name: Willemsen, Marc C.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 2. Coding scheme.
Investigation of background in large-area neutron detectors due to alpha emission from impurities in aluminium
Creators: name: Birch, J.
name: Buffet, J. -C.
name: Clergeau, J. -F.
name: van Esch, P.
name: Ferraton, M.
name: Guerard, B.
name: Hall-Wilton, R.
name: Hultman, L.
name: Höglund, C.
name: Jensen, J.
name: Khaplanov, A.
name: Piscitelli, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Thermal neutron detector based on films of $^{10}$B$_4$C have been developed as an alternative to $^3$He detectors. In particular, The Multi-Grid detector concept is considered for future large area detectors for ESS and ILL instruments. An excellent signal-to-background ratio is essential to attain expected scientific results. Aluminium is the most natural material for the mechanical structure of of the Multi-Grid detector and other similar concepts due to its mechanical and neutronic properties. Due to natural concentration of $α$ emitters, however, the background from $α$ particles misidentified as neutrons can be unacceptably high. We present our experience operating a detector prototype affected by this issue. Monte Carlo simulations have been used to confirm the background as $α$ particles. The issues have been addressed in the more recent implementations of the Multi-Grid detector by the use of purified aluminium as well as Ni-plating of standard aluminium. The result is the reduction in background by two orders of magnitude. A new large-area prototype has been built incorporating these modifications.
description: 14 pages, 8 figures. Submission to Journal of Instrumentation new version uploaded addressing referee comments (minor revision). Added discussion of radon contamination and more details on simulated spectra
Selaginella producta Baker, J. Bot.
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Lycopodiopsida
Selaginellales
Selaginellaceae
Selaginella
Selaginella producta

description: Selaginella producta Baker, J. Bot. 21: 243. 1883.
 Range: — Trinidad and Tobago, Guianas to Colombia, Brazil, and Bolivia (PA).
 Ecology: —Rare; Amazonian rain forests; to 500 m.
 Notes: —The only Bolivian collection of Selaginella producta differs from typical material by the less strongly acuminate median leaves, less pronounced midribs, and rather dull and more planar leaves; it may represent a distinct species.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. III. Selaginellaceae, pp. 248-258 in Phytotaxa 344 (3) on page 255, DOI: 10.11646/phytotaxa.344.3.5, http://zenodo.org/record/13719508
APOBEC3G and APOBEC3F Act in Concert To Extinguish HIV-1 Replication
Creators: name: Baker, Caroline E.
name: Krisko, John F.
name: Garcia, J. Victor
name: Foster, John L.
name: Begum, Nurjahan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: ABSTRACT The multifunctional HIV-1 accessory protein Vif counters the antiviral activities of APOBEC3G (A3G) and APOBEC3F (A3F), and some Vifs counter stable alleles of APOBEC3H (A3H). Studies in humanized mice have shown that HIV-1 lacking Vif expression is not viable. Here, we look at the relative contributions of the three APOBEC3s to viral extinction. Inoculation of bone marrow/liver/thymus (BLT) mice with CCR5-tropic HIV-1 JRCSF (JRCSF) expressing a vif gene inactive for A3G but not A3F degradation activity (JRCSFvifH42/43D) displayed either no or delayed replication. JRCSF expressing a vif gene mutated to inactivate A3F degradation but not A3G degradation (JRCSFvifW79S) always replicated to high viral loads with variable delays. JRCSF with vif mutated to lack both A3G and A3F degradation activities (JRCSFvifH42/43DW79S) failed to replicate, mimicking JRCSF without Vif expression (JRCSFΔvif). JRCSF and JRCSFvifH42/43D, but not JRCSFvifW79S or JRCSFvifH42/43DW79S, degraded APOBEC3D. With one exception, JRCSFs expressing mutant Vifs that replicated acquired enforced vif mutations. These mutations partially restored A3G or A3F degradation activity and fully replaced JRCSFvifH42/43D or JRCSFvifW79S by 10 weeks. Surprisingly, induced mutations temporally lagged behind high levels of virus in blood. In the exceptional case, JRCSFvifH42/43D replicated after a prolonged delay with no mutations in vif but instead a V27I mutation in the RNase H coding sequence. JRCSFvifH42/43D infections exhibited massive GG/AG mutations in pol viral DNA, but in viral RNA, there were no fixed mutations in the Gag or reverse transcriptase coding sequence. A3H did not contribute to viral extinction but, in combination with A3F, could delay JRCSF replication. A3H was also found to hypermutate viral DNA. IMPORTANCE Vif degradation of A3G and A3F enhances viral fitness, as virus with even a partially restored capacity for degradation outgrows JRCSFvifH42/43D and JRCSFvifW79S. Unexpectedly, fixation of mutations that replaced H42/43D or W79S in viral RNA lagged behind the appearance of high viral loads. In one exceptional JRCSFvifH42/43D infection, vif was unchanged but replication proceeded after a long delay. These results suggest that Vif binds and inhibits the non-cytosine deaminase activities of intact A3G and intact A3F, allowing JRCSFvifH42/43D and JRCSFvifW79S to replicate with reduced fitness. Subsequently, enhanced Vif function is acquired by enforced mutations. In infected cells, JRCSFΔvif and JRCSFvifH42/43DW79S are exposed to active A3F and A3G and fail to replicate. JRCSFvifH42/43D Vif degrades A3F and, in some cases, overcomes A3G mutagenic activity to replicate. Vif may have evolved to inhibit A3F and A3G by stoichiometric binding and subsequently acquired the ability to target these proteins to proteasomes.
EDUCATION IS THE ANSWER TO SUSTAINABLE DEVELOPMENT
Creators: name: DR. Manju Garg1   Mrs. Tamanna2
Publisher: name: Zenodo
Year: 2022
Subjects: Development, Education, Sustainable

description: Abstract: - Education is a valuable resource of knowledge. It facilitates quality of learning all throughout our lives. It is in fact a complete holistic sustainable education system that lays the foundation of our wisdom, character and ethics. These also play a vital role in our overall development and the progress of our society as a whole. Education for sustainable development (ESD) promotes the development of the knowledge, skills, understanding, values and actions required to create a sustainable world, which ensures environmental protection and conservation, promotes social equity and encourages economic sustainability. Education for sustainable development is a vision of education that seeks to balance human and economic well-being with cultural traditions and respect for the Earth’s natural resources. It emphasizes aspects of learning that enhance the transition towards sustainability including future education; citizenship education; education for a culture of peace; gender equality and respect for human rights; health education; population education; education for protecting and managing natural resources; and education for sustainable consumption. Educational approaches must take into account the experiences of indigenous cultures and minorities, acknowledging and facilitating their original and important contributions to the process of sustainable development.
Selaginella revoluta Baker, J. Bot.
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Lycopodiopsida
Selaginellales
Selaginellaceae
Selaginella
Selaginella revoluta

description: Selaginella revoluta Baker, J. Bot. 21: 141. 1883.
 Range: — Panama to Bolivia (CO), Venezuela, Guianas, and Amazonian Brazil.
 Ecology: —Rare, known from a single Bolivian collection (Kessler 8820, LPB, UC); terrestrial, often forming dense mats in humid forests; 200 m.
 Notes: — Selaginella brevifolia Baker, from Amazonia, may occur in northern Bolivia. It differs from S. revoluta by median leaves with prolonged auricles (vs. lacking auricles), and from S. novae-hollandiae by bearing rhizophores along the stems and branches, and its strongly prostrate habit (vs. suberect, lacking rhizophores above the proximal third of stems). Selaginella revoluta also lacks sobols at the base of the main stems (vs. sobols usually present).
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. III. Selaginellaceae, pp. 248-258 in Phytotaxa 344 (3) on page 255, DOI: 10.11646/phytotaxa.344.3.5, http://zenodo.org/record/13719508
Penalized power properties of the normality tests in the presence of outliers
Creators: name: Cavus, Mustafa
name: Yazici, Berna
name: Sezer, Ahmet
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Mathematical Sciences not elsewhere classified
subject: Mental Health

description: The assumption of normality has a crucial importance in many statistical procedures. Therefore, a number of normality tests are proposed. Also, many investigations are conducted on the performance of these normality tests under a set of alternative distribution. However, there are few studies to compare the performance of the commonly used normality tests in the presence of outliers, but they are not comprehensive. It is important, since the outliers may increase the variability in the data set, they cause the decrease in the statistical power. In this study we show the performance of the commonly used normality tests in the presence of outlier in the data set. An outlier generation method is implied to generate uniform tails and the effects of various magnitude of outliers on the normality tests are obtained in terms of penalized power and Type I error probability. As a result, the most powerful tests are suggested to the researchers for different magnitude of outliers, sample sizes and the contamination ratios. Two real data applications are given to illustrate the importance of choosing the appropriate test.
The Ground State of Monolayer Graphene in a Strong Magnetic Field
Creators: name: Wu, Lian-Ao
name: Guidry, Mike
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Graphene SU(4) quantum Hall symmetry is extended to SO(8), permitting analytical solutions for graphene in a magnetic field that break SU(4) spontaneously. We recover standard graphene SU(4) physics as one limit, but find new phases and new properties that may be relevant for understanding the ground state. The graphene SO(8) symmetry is found to be isomorphic to one that occurs extensively in nuclear structure physics, and very similar to one that describes high-temperature superconductors, suggesting deep mathematical connections among these physically-different fermionic systems.
Selaginella sellowii Hieron., Hedwigia
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Lycopodiopsida
Selaginellales
Selaginellaceae
Selaginella
Selaginella sellowii

description: Selaginella sellowii Hieron., Hedwigia 39: 306. 1900.
 Range: — Cuba; central and southern Mexico; Venezuela to Bolivia (CH, CO, LP, SC, TA) and central Argentina; eastern Brazil.
 Ecology: —Common; terrestrial in arid regions, often covering the ground in overgrazed dry forests, also on and among rocks; to 3700 m.
 Notes: —Leafy stems generally more slender than in S. peruviana and more bluish gray. The leaf bases are often decurrent on upper side of stems, and leaf tips are not curled when dry.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. III. Selaginellaceae, pp. 248-258 in Phytotaxa 344 (3) on page 255, DOI: 10.11646/phytotaxa.344.3.5, http://zenodo.org/record/13719508
Surface Transport in the ν=0 Quantum Hall Ferromagnetic State in the Organic Dirac Fermion System
Creators: name: Osada, Toshihito
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We discuss the surface magnetotransport in the quantum Hall (QH) ferromagnetic state expected in the organic Dirac fermion system α-(BEDT-TTF)_2I_3. The QH ferromagnetic state is one of the possible ν=0 QH states in the two-dimensional Dirac fermion system resulting from the degeneracy breaking of the n=0 Landau level. It is characterized by the helical edge state. We have studied the interlayer surface transport via helical edge state in the multilayer QH ferromagnet, in which the bulk region is insulating. We have clarified that the surface conductivity is much less than e^2/h and decreases as the magnetic field is tilted to the normal direction of the side surface. These features explain the observed interlayer magnetoresistance in α-(BEDT-TTF)_2I_3.
description: 16 pages, 4 figures
Template zur Protokollierung von Beratungsvorgängen im Forschungsdatenmanagement
Creators: name: Helling, Patrick
Publisher: name: Zenodo
Year: 2023
Subjects: Forschungsdatenmanagement
DCH
Data Center for the Humanities
FDM
Protokoll
Template
FDM-Beratung

description: Protokolltemplate zur Dokumentation von Forschungsdatenmanagement-Beratungsvorgängen am Data Center for the Humanities (DCH) an der Philosophischen Fakultät der Universität zu Köln. Das Template besteht aus drei Abschnitten: Metainformationen zu einem Beratungsvorgang Inhaltliche Aspekte eines Beratungsgesprächs Vorgehensweise zur Bedienung eines (oder mehrerer) Forschungsdatenmanagement-Bedarfe Ein Beratungsvorgang kann aus mehreren Beratungsgesprächen bestehen, die in einem gemeinsamen Protokoll-Template dokumentiert werden. Bei mehreren Beratungsgesprächen innerhalb eines Beratungsvorgangs bleibt der Bereich "Metainformationen zu einem Beratungsvorgang" i.d.R. identisch.
Additional file 3 of “If the social circle is engaged, more pregnant women will successfully quit smoking”: a qualitative study of the experiences of midwives in the Netherlands with smoking cessation care
Creators: name: Willemse, Eefje
name: Walters, Bethany Hipple
name: Springvloet, Linda
name: Bommelé, Jeroen
name: Willemsen, Marc C.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 3. Identification of themes.
BIO-MEDICAL WASTE DISPOSAL AND MANAGEMENT OF DHARWAD CIVIL HOSPITAL: A CASE STUDY
Creators: name: Dr. I. A. Mulla
Publisher: name: Zenodo
Year: 2022

description: Abstract: Solid waste generation has proven to be a major concern to people, especially in urban areas. It has made living difficult and brought about several serious issues in the cities. Waste management and disposal have become challenging tasks for any government, its agencies, and enterprises. The public, governments, and other organizations have focused attention on the disposal of hazardous wastes and the release of toxic substances in the environment as a result of the discovery of toxic chemicals in the water supply, fruits and vegetables, and water tables and the risk they pose to human health. The Hazardous Waste (Management and Handling Rules) were published by the Ministry of Environment and Forests (India) in 1989 and were updated in 2000. It is a comprehensive act dealing with all facets of environmental protection. Municipal solid trash generation and increased industrial production have posed a significant issue and necessitated skilled administrative measures. Therefore, the researcher has chosen the current issue to understand the multiple implications of waste.
On the role of chalcogen vapor annealing in inducing bulk superconductivity in Fe$_{1+y}$Te$_{1-x}$Se$_{x}$
Creators: name: Lin, Wenzhi
name: Ganesh, P.
name: Gianfrancesco, Anthony
name: Wang, Jun
name: Berlijn, Tom
name: Maier, Thomas A.
name: Kalinin, Sergei V.
name: Sales, Brian C.
name: Pan, Minghu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Recent investigations have shown that Fe$_{1+y}$Te$_{1-x}$Se$_{x}$ can be made superconducting by annealing it in Se and O vapors. The current lore is that these chalcogen vapors induce superconductivity by removing the magnetic excess Fe atoms. To investigate this phenomenon we performed a combination of magnetic susceptibility, specific heat and transport measurements together with scanning tunneling microscopy and spectroscopy and density functional theory calculations on Fe$_{1+y}$Te$_{1-x}$Se$_{x}$ treated with Te vapor. We conclude that the main role of the Te vapor is to quench the magnetic moments of the excess Fe atoms by forming FeTe$_{m}$ (m $\geq$ 1) complexes. We show that the remaining FeTe$_{m}$ complexes are still damaging to the superconductivity and therefore that their removal potentially could further improve superconductive properties in these compounds.
On the representation of many-body interactions in water
Creators: name: Medders, Gregory R.
name: Gotz, Andreas W.
name: Morales, Miguel A.
name: Paesani, Francesco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Recent work has shown that the many-body expansion of the interaction energy can effectively be used to develop analytical representations of global potential energy surfaces (PESs) for water. In this study, the role of short- and long-range contri- butions at different orders is investigated by analyzing water potentials that treat the leading terms of the many-body expansion through implicit (i.e., TTM3-F and TTM4-F PESs) and explicit (i.e., WHBB and MB-pol PESs) representations. It is found that explicit short-range representations of 2-body and 3-body interactions along with a physically correct integration of short- and long-range contributions are necessary for an accurate representation of the water interactions from the gas to the condensed phase. Similarly, a complete many-body representation of the dipole moment surface is found to be crucial to reproducing the correct intensities of the infrared spectrum of liquid water.
A novel algorithm for generating minimum energy points from identically charged particles in 1D, 2D and 3D unit hypercubes
Creators: name: Elsawah, A. M.
name: Hua, Li Meng
name: Fang, Kai-Tai
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Generating minimum energy points (MEPs) is an optimal solution of many real-world problems, such as the selection of best locations for hospitals inside a city that reduce the overcrowding and competition and avoid the less-populated regions. The key idea is considering these locations as charged particles with the same sign (i.e., repel each other) inside a box and distribute these points by minimizing the total electric potential energy (TEPE) among them. The practice demonstrated that most of the existing techniques for generating MEPs are complex, especially for non-mathematicians. Therefore, the greedy algorithm (GreA) is the classical widely used algorithm for its simplicity even though a satisfactory result is not guaranteed. This paper gives a novel algorithm for generating MEPs from identically charged particles in 1D, 2D and 3D unit hypercubes. The results show that the new algorithm distributes the points far away from each other to reduce the TEPE of the generated MEPs more effectively than the GreA. The new algorithm is a significant improvement of the GreA to overcome its unsatisfactory results. Therefore, the new algorithm in its current form or after some improvements is highly recommended to be used instead of the GreA for many different applications.
Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site
Creators: name: Halder, Sujata
name: Miller, Edward Blake
name: Asokan, Aravind
name: McKenna, Robert
name: Agbandje-McKenna, Mavis
name: Huang, Lin-Ya
name: Ng, Robert
name: Patel, Ami
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: ABSTRACT The adeno-associated viruses (AAVs), which are being developed as gene delivery vectors, display differential cell surface glycan binding and subsequent tissue tropisms. For AAV serotype 1 (AAV1), the first viral vector approved as a gene therapy treatment, and its closely related AAV6, sialic acid (SIA) serves as their primary cellular surface receptor. Toward characterizing the SIA binding site(s), the structure of the AAV1-SIA complex was determined by X-ray crystallography to 3.0 Å. Density consistent with SIA was observed in a pocket located at the base of capsid protrusions surrounding icosahedral 3-fold axes. Site-directed mutagenesis substitution of the amino acids forming this pocket with structurally equivalent residues from AAV2, a heparan sulfate binding serotype, followed by cell binding and transduction assays, further mapped the critical residues conferring SIA binding to AAV1 and AAV6. For both viruses five of the six binding pocket residues mutated (N447S, V473D, N500E, T502S, and W503A) abolished SIA binding, whereas S472R increased binding. All six mutations abolished or decreased transduction by at least 50% in AAV1. Surprisingly, the T502S substitution did not affect transduction efficiency of wild-type AAV6. Furthermore, three of the AAV1 SIA binding site mutants—S472R, V473D, and N500E—escaped recognition by the anti-AAV1 capsid antibody ADK1a. These observations demonstrate that common key capsid surface residues dictate both virus binding and entry processes, as well as antigenic reactivity. This study identifies an important functional capsid surface “hot spot” dictating receptor attachment, transduction efficiency, and antigenicity which could prove useful for vector engineering. IMPORTANCE The adeno-associated virus (AAV) vector gene delivery system has shown promise in several clinical trials and an AAV1-based vector has been approved as the first gene therapy treatment. However, limitations still exist with respect to transduction efficiency and the detrimental effects of preexisting host antibodies. This study aimed to identify key capsid regions which can be engineered to overcome these limitations. A sialic glycan receptor recognition pocket was identified in AAV1 and its closely related AAV6, using X-ray crystallography. The site was confirmed by mutagenesis followed by cell binding and transduction assays. Significantly, residues controlling gene expression efficiency, as well as antibody escape variants, were also identified. This study thus provides, at the amino acid level, information for rational structural engineering of AAV vectors with improved therapeutic efficacy.
Additional file 3 of A method for labelling lesions for machine learning and some new observations on osteochondrosis in computed tomographic scans of four pig joints
Creators: name: Olstad, Kristin
name: Gangsei, Lars Erik
name: Kongsro, Jørgen
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 3: Supplemental Table 1. Annotations in the first 10 pigs.
Axion Cosmology
Creators: name: Marsh, David J. E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: 1. Introduction 2. Models: the QCD axion; the strong CP problem; PQWW, KSVZ, DFSZ; anomalies, instantons and the potential; couplings; axions in string theory 3. Production and I.C.'s: SSB and non-perturbative physics; the axion field during inflation and PQ SSB; cosmological populations - decay of parent, topological defects, thermal production, vacuum realignment 4. The Cosmological Field: action; background evolution; misalignment for QCD axion and ALPs; cosmological perturbation theory - i.c.'s, early time treatment, axion sound speed and Jeans scale, transfer functions and WDM; the Schrodinger picture; simualting axions; BEC 5. CMB and LSS: Primary anisotropies; matter power; combined constraints; Isocurvature and inflation 6. Galaxy Formation; halo mass function; high-z and the EOR; density profiles; the CDM small-scale crises 7. Accelerated expansion: the c.c. problem; axion inflation (natural and monodromy) 8. Gravitational interactions with black holes and pulsars 9. Non-gravitational interactions: stellar astrophysics; LSW; vacuum birefringence; axion forces; direct detection with ADMX and CASPEr; Axion decays; dark radiation; astrophysical magnetic fields; cosmological birefringence 10. Conclusions A Theta vacua of gauge theories B EFT for cosmologists C Friedmann equations D Cosmological fluids E Bayes Theorem and priors F Degeneracies and sampling G Sheth-Tormen HMF
description: v2 greatly extended: 111 pages, 38 figures. Accepted for publication in Physics Reports
Pauli-Villars Regularization and Light Front Hamiltonian in (2+1)-dimensional Yang-Mills Theory
Creators: name: Malyshev, M. Yu.
name: Paston, S. A.
name: Prokhvatilov, E. V.
name: Zubov, R. A.
name: Franke, V. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The renormalization problem of (2+1)-dimensional Yang-Mills theory quantized on the light front is considered. Extra fields analogous to those used in Pauli-Villars regularization are introduced to restore perturbative equivalence between such quantized theory and conventional formulation in Lorentz coordinates. These fields also provide necessary ultraviolet regularization to the theory. Obtained results allow to construct renormalized Hamiltonian of the theory on the light front.
description: LaTeX, 12 pages, 2 figures. Article will be published in Theoretical and Mathematical Physics, the final publication will be available at http://link.springer.com/journal/11232
Deep Sequencing of the HIV-1 env Gene Reveals Discrete X4 Lineages and Linkage Disequilibrium between X4 and R5 Viruses in the V1/V2 and V3 Variable Regions
Creators: name: Hauser, Blake M.
name: Swanstrom, Ronald
name: Bednar, Maria M.
name: Zhou, Shuntai
name: Sturdevant, Christa B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: ABSTRACT HIV-1 requires the CD4 receptor and a coreceptor (CCR5 [R5 phenotype] or CXCR4 [X4 phenotype]) to enter cells. Coreceptor tropism can be assessed by either phenotypic or genotypic analysis, the latter using bioinformatics algorithms to predict tropism based on the env V3 sequence. We used the Primer ID sequencing strategy with the MiSeq sequencing platform to reveal the structure of viral populations in the V1/V2 and C2/V3 regions of the HIV-1 env gene in 30 late-stage and 6 early-stage subjects. We also used endpoint dilution PCR followed by cloning of env genes to create pseudotyped virus to explore the link between genotypic predictions and phenotypic assessment of coreceptor usage. We found out that the most stringently sequence-based calls of X4 variants (Geno2Pheno false-positive rate [FPR] of ≤2%) formed distinct lineages within the viral population, and these were detected in 24 of 30 late-stage samples (80%), which was significantly higher than what has been seen previously by using other approaches. Non-X4 lineages were not skewed toward lower FPR scores in X4-containing populations. Phenotypic assays showed that variants with an intermediate FPR (2 to 20%) could be either X4/dual-tropic or R5 variants, although the X4 variants made up only about 25% of the lineages with an FPR of <10%, and these variants carried a distinctive sequence change. Phylogenetic analysis of both the V1/V2 and C2/V3 regions showed evidence of recombination within but very little recombination between the X4 and R5 lineages, suggesting that these populations are genetically isolated. IMPORTANCE Primer ID sequencing provides a novel approach to study genetic structures of viral populations. X4 variants may be more prevalent than previously reported when assessed by using next-generation sequencing (NGS) and with a greater depth of sampling than single-genome amplification (SGA). Phylogenetic analysis to identify lineages of sequences with intermediate FPR values may provide additional information for accurately predicting X4 variants by using V3 sequences. Limited recombination occurs between X4 and R5 lineages, suggesting that X4 and R5 variants are genetically isolated and may be replicating in different cell types or that X4/R5 recombinants have reduced fitness.
Caustic Structures and Detectability of Circumbinary Planets in Microlensing
Creators: name: Luhn, Jacob K.
name: Penny, Matthew T.
name: Gaudi, B. Scott
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Recent discoveries of circumbinary planets in Kepler data show that there is a viable channel of planet formation around binary main sequence stars. Motivated by these discoveries, we have investigated the caustic structures and detectability of circumbinary planets in microlensing events. We have produced a suite of animations of caustics as a function of the projected separation and angle of the binary host to efficiently explore caustic structures over the entire circumbinary parameter space. Aided by these animations, we have derived a semi-empirical analytic expression for the location of planetary caustics, which are displaced in circumbinary lenses relative to those of planets with a single host. We have used this expression to show that the dominant source of caustic motion will be due to the planet's orbital motion and not that of the binary star. Finally, we estimate the fraction of circumbinary microlensing events that are recognizable as such to be significant (5-50 percent) for binary projected separations in the range 0.1-0.5 in units of Einstein radii.
description: 15 pages, 1 table, 18 figures. Accepted for publication in ApJ
Optical inverse-Compton emission from clusters of galaxies
Creators: name: Yamazaki, Ryo
name: Loeb, Abraham
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Shocks around clusters of galaxies accelerate electrons which upscatter the Cosmic Microwave Background photons to higher-energies. We use an analytical model to calculate this inverse Compton (IC) emission, taking into account the effects of additional energy losses via synchrotron and Coulomb scattering. We find that the surface brightness of the optical IC emission increases with redshift and halo mass. The IC emission surface brightness, 32--34~mag~arcsec$^{-2}$, for massive clusters is potentially detectable by the newly developed Dragonfly Telephoto Array.
description: 11 pages, 7 figures, 1 table, accepted for publication in MNRAS
Additional file 4 of A method for labelling lesions for machine learning and some new observations on osteochondrosis in computed tomographic scans of four pig joints
Creators: name: Olstad, Kristin
name: Gangsei, Lars Erik
name: Kongsro, Jørgen
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 4: Supplemental Table 2. Intra-observer agreement on whether an anatomical region was positive or negative for osteochondrosis.
Penalized power properties of the normality tests in the presence of outliers
Creators: name: Cavus, Mustafa
name: Yazici, Berna
name: Sezer, Ahmet
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Mathematical Sciences not elsewhere classified
subject: Mental Health

description: The assumption of normality has a crucial importance in many statistical procedures. Therefore, a number of normality tests are proposed. Also, many investigations are conducted on the performance of these normality tests under a set of alternative distribution. However, there are few studies to compare the performance of the commonly used normality tests in the presence of outliers, but they are not comprehensive. It is important, since the outliers may increase the variability in the data set, they cause the decrease in the statistical power. In this study we show the performance of the commonly used normality tests in the presence of outlier in the data set. An outlier generation method is implied to generate uniform tails and the effects of various magnitude of outliers on the normality tests are obtained in terms of penalized power and Type I error probability. As a result, the most powerful tests are suggested to the researchers for different magnitude of outliers, sample sizes and the contamination ratios. Two real data applications are given to illustrate the importance of choosing the appropriate test.
title: Five-year progression of radiographic sacroiliitis in patients with axial spondyloarthritis in ASAS cohort: data of central reading
Creators: name: Protopopov, Mikhail
name: Proft, Fabian
name: Sepriano, Alexandre
name: Landewé, Robert
name: van der Heijde, Desiree
name: Sieper, Joachim
name: Rudwaleit, Martin
name: Poddubnyy, Denis
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Radiographic progression of sacroiliitis in axial spondyloarthritis (axSpA) is slow, with only few predictors identified. An analysis of data from Ankylosing Spondylitis Assessment Society (ASAS) Cohort, based on local assessment of radiographs, revealed surprisingly high rate of regression[for full text, please go to the a.m. URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)