cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Κατασκευή και μελέτη επιδόσεων των συσκευών επαγωγικών πηνίων Barbat
title: Construction and performance study of Barbat induction coil devices
titleType: AlternativeTitle
Creators: name: Βασιλόπουλος, Αθανάσιος
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Barbat πηνία
Επαγωγικά πηνία
Μετασχηματιστές
Πυκνωτές

description: Η παρούσα διπλωματική εργασία ασχολείται με τη μελέτη, την κατασκευή, καθώς και την αξιολόγηση της λειτουργίας μίας συσκευής δύο επαγωγικών πηνίων τύπου Barbat από χάλκινο σύρμα, τα οποία αξιοποιούν τον γεωστατικό ηλεκτρισμό για την παραγωγή ηλεκτρικής ισχύος. Στόχος της εργασίας είναι η ανάπτυξη ενός νέου τρόπου παραγωγής ηλεκτρικής ισχύος με σκοπό την αυτονομία και την καθημερινή αξιοποίησή του τόσο από οικιακούς χρήστες, όσο και από μεγαλύτερες μονάδες κατανάλωσης ηλεκτρικής ενέργειας. Η χρήση αυτής της τεχνολογίας έχει σαν πρόθεση όχι μόνο την αντικατάσταση της παραγωγής ηλεκτρικής ενέργειας από τις μέχρι τώρα συμβατικές μορφές, δηλαδή την καύση κάποιας ύλης, αλλά και την αποδέσμευση από την ανάγκη των εναλλακτικών Ανανεώσιμων Πηγών Ενέργειας (Α.Π.Ε.). Είναι δυνατό να βρει έδαφος εκμετάλλευσης σε διάφορους τομείς, όπως αυτοί της βιομηχανίας και των μεταφορών, όμως το κυριότερο ενδιαφέρον της εστιάζει στην κάλυψη των καθημερινών αναγκών του μέσου καταναλωτή. Ένα μεγάλο πλεονέκτημα της συσκευής είναι το σχετικά χαμηλό επίπεδο κόστους της υλοποίησης, χρησιμοποιώντας υλικά που βρίσκονται εύκολα στο εμπόριο, με αποτέλεσμα να είναι προσιτή στον κάθε ενδιαφερόμενο. Ακόμα, το μικρό μέγεθος και βάρος, κάνουν την αποθήκευση και τη μεταφορά εφικτές χωρίς ιδιαίτερη δυσκολία. Τα βασικά στοιχεία που την απαρτίζουν είναι δύο πηνία πυρήνα αέρα, ένα πρωτεύον και ένα δευτερεύον, που συνδέονται μεταξύ τους επαγωγικά, φτιαγμένα από σύρμα χαλκού, μία κάθετη σε αυτά επιφάνεια που λειτουργεί ως πυκνωτής, έναν αντιστροφέα (inverter), έναν μετασχηματιστή νέον (neon transformer) και η βάση πάνω στην οποία στερεώνονται.
Pereira EMBO J. 2017.pdf
Creators: name: Pereira, Renata Oliveira
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 60603 Animal Physiology - Systems
subject: FOS: Biological sciences

description: Mitochondrial dynamics is a conserved process by which mitochondria undergo repeated cycles of fusion and fission, leading to exchange of mitochondrial genetic content, ions, metabolites, and proteins. Here, we examine the role of the mitochondrial fusion protein optic atrophy 1 (OPA1) in differentiated skeletal muscle by reducing OPA1 gene expression in an inducible manner. OPA1 deficiency in young mice results in non-lethal progressive mitochondrial dysfunction and loss of muscle mass. Mutant mice are resistant to age- and diet-induced weight gain and insulin resistance, by mechanisms that involve activation of ER stress and secretion of fibroblast growth factor 21 (FGF21) from skeletal muscle, resulting in increased metabolic rates and improved whole-body insulin sensitivity. OPA1-elicited mitochondrial dysfunction activates an integrated stress response that locally induces muscle atrophy, but via secretion of FGF21 acts distally to modulate whole-body metabolism.
Phase transitions in anisotropic superconducting and magnetic systems with vector order parameters: Three-loop renormalization-group analysis
Creators: name: Antonenko, S. A.
name: Sokolov, A. I.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Superconductivity (cond-mat.supr-con)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The critical behavior of a model with N-vector complex order parameter and three quartic coupling constants that describes phase transitions in unconventional superconductors, helical magnets, stacked triangular antiferromagnets, superfluid helium-3, and zero-temperature transitions in fully frustrated Josephson-junction arrays is studied within the field- theoretical renormalization-group approach in three dimensions. To obtain qualitatively and quantitatively correct results perturbative expansions for β-functions and critical exponents are calculated up to three-loop order and resummed by means of the generalized Pade-Borel procedure. Fixed-point coordinates, critical exponent values, RG flows, etc. are found for the physically interesting cases N = 2 and N = 3. Marginal values of N at which the topology of the flow diagram changes are determined as well. In most cases the systems mentioned are shown to undergo fluctuation-driven first-order phase transitions. Continuous transitions are allowed in hexagonal d-wave superconductors, in planar helical magnets (into sinusoidal linearly-polarized phase), and in triangular antiferromagnets (into simple unfrustrated ordered states) with critical exponents γ= 1.336, ν= 0.677, α= -0.030, β= 0.347, η= 0.026, which are hardly believed to be experimentally distinguishable from those of the 3D XY model. The chiral fixed point of RG equations is found to exist and possess some domain of attraction provided N > 3. Thus, magnets with Heisenberg (N = 3) and XY-like (N = 2) spins should not demonstrate chiral critical behavior with unusual critical exponents; they can approach the chiral state only via first-order phase transitions.
description: 22 pages, LaTeX, no figures
Additional file 4 of Microbial community structure and composition is associated with host species and sex in Sigmodon cotton rats
Creators: name: Strickland, Britton A.
name: Patel, Mira C.
name: Shilts, Meghan H.
name: Boone, Helen H.
name: Kamali, Arash
name: Zhang, Wei
name: Stylos, Daniel
name: Boukhvalova, Marina S.
name: Rosas-Salazar, Christian
name: Yooseph, Shibu
name: Rajagopala, Seesandra V.
name: Blanco, Jorge C. G.
name: Das, Suman R.
Publisher: name: figshare
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 4: Figure S4. PCoA plots comparing Bray-Curtis dissimilarities between body sites in both (A) S. hispidus and (B) S. fulviventer.
Copper aggravated synaptic damage after traumatic brain injury by downregulating BNIP3-mediated mitophagy
Creators: name: Chang, Hanxiao
name: Zhang, Weiwei
name: Xu, Lei
name: Li, Zheng
name: Lin, Chao
name: Shen, Yuqi
name: Zhang, Guangjian
name: Mao, Lei
name: Ma, Chencheng
name: Liu, Ning
name: Lu, Hua
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Synaptic damage is a crucial pathological process in traumatic brain injury. However, the mechanisms driving this process remain poorly understood. In this report, we demonstrate that the accumulation of damaged mitochondria, resulting from impaired mitphagy, plays a significant role in causing synaptic damage. Moreover, copper induced downregulation of BNIP3 is a key player in regulating mitophagy. DMSA alleviates synaptic damage and mitochondrial dysfunction by promoting urinary excretion of copper. Mechanistically, we find that copper downregulate BNIP3 by increasing the nuclear translocation of NFKB, which is triggered by TRIM25-mediated ubiquitination-dependent degradation of NFKBIA. Our study underscores the importance of copper accumulation in the regulation of BNIP3-mediated mitophagy and suggests that therapeutic targeting of the copper-TRIM25-NFKB-BNIP3 axis holds promise to attenuate synaptic damage after traumatic brain injury.
title: Δημιουργία εταιρικής ταυτότητας, ιστοσελίδας και προωθητικών εφαρμογών
title: Creation of corporate identity, website and promotional applications
titleType: AlternativeTitle
Creators: name: Υακίνθου, Ευαγγελία
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Μόδα
Επαναχρησιμοποίηση
Ηθική μόδα
Οικολογία
Thrifting

description: Η παρούσα πτυχιακή εργασία επικεντρώνεται στον σχεδιασμό της οπτικής ταυτότητας και της ιστοσελίδας (eshop) για μια εταιρεία thrift shop. Η αγορά της μόδας κάθε μέρα πολλαπλασιάζεται και ο καταναλωτισμός αυξάνεται. Η εταιρεία προσφέρει την μέθοδο αγοράς μεταχειρισμένων ρούχων που βοηθά στην μείωση της επιβάρυνσης του περιβάλλοντος αλλά και στην ευαισθητοποίηση του κοινού σχετικά με την ηθική μόδα. Η εργασία αναλύει τον ρόλο της εταιρικής ταυτότητας και πώς αλληλεπιδρά στους καταναλωτές. Στο πλαίσιο της εργασίας, αναλύονται ο ορισμός της εταιρικής ταυτότητας, ο ρόλος της στο σχεδιασμό, η αξία του brand και άλλα απαραίτητα στοιχεία του οπτικού σχεδιασμού. Στόχος είναι να δημιουργηθεί μια νέα εταιρεία βασισμένη στις αρχές αυτές. Εκτός της εταιρικής-οπτικής ταυτότητας και της ιστοσελίδας θα δημιουργηθούν εφαρμογές όπως η διαφήμιση και η προωθητική καμπάνια της εταιρείας στην αγορά.
Caladium nymphaeifolium Vent.
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Alismatales
Araceae
Caladium
Caladium nymphaeifolium

description: 11. Caladium nymphaeifolium Vent. in Mag. Encycl. 4: 471. 1801 [cited in Descr. Pl. Nouv.: sub tab. 30. 1801].
 Lectotypus (designated here): [INDONESIA]: “ Wali Ila ”, (Rheede, Hort. Malab. 9: tab. 22. 1689).
 = Colocasia esculenta (L.) Schott
 Notes. – Despite a search for original material of this species at G and P, no collection has been located. The name Caladium nymphaeifolium was validated by Ventenat in Descriptions in 1801 in the text below the description of Caladium bicolor (Ait.) Vent. with no illustration but with a clear reference to Hortus Malabricus vol. 9 (Rheede, 1689): “une espèce que j’ai trouvée dans l’herbier Jussieu, qui est figurée dans le IXème vol. de l’Hort. Malabar., t. 22, et à laquelle j’ai donné le nom de nymphaeifolium.” [“a species that I found in the Jussieu herbarium, which is illustrated in the ninth vol. of the Hort. Malabar., t. 22, and to which I gave the name of nymphaeifolium.”]. Until original material is located, we designate tab. 22 in Rheede (1689) as the lectotype.
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on pages 98-100, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
Design and Implementation of the ABRACADABRA-10 cm Axion Dark Matter Search
Creators: name: Ouellet, Jonathan L.
name: Salemi, Chiara P.
name: Foster, Joshua W.
name: Henning, Reyco
name: Bogorad, Zachary
name: Conrad, Janet M.
name: Formaggio, Joseph A.
name: Kahn, Yonatan
name: Minervini, Joe
name: Radovinsky, Alexey
name: Rodd, Nicholas L.
name: Safdi, Benjamin R.
name: Thaler, Jesse
name: Winklehner, Daniel
name: Winslow, Lindley
Publisher: name: arXiv
Year: 2019
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The past few years have seen a renewed interest in the search for light particle dark matter. ABRACADABRA is a new experimental program to search for axion dark matter over a broad range of masses, $10^{-12}\lesssim m_a\lesssim10^{-6}$ eV. ABRACADABRA-10 cm is a small-scale prototype for a future detector that could be sensitive to QCD axion couplings. In this paper, we present the details of the design, construction, and data analysis for the first axion dark matter search with the ABRACADABRA-10 cm detector. We include a detailed discussion of the statistical techniques used to extract the limit from the first result with an emphasis on creating a robust statistical footing for interpreting those limits.
description: 12 pages, 8 figures
SMURF1 mediates damaged lysosomal homeostasis by ubiquitinating PPP3CB to promote the activation of TFEB
Creators: name: Xia, Qin
name: Liu, Xuan
name: Zhong, Lu
name: Qu, Jun
name: Dong, Lei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Hematology

description: The calcium-activated phosphatase PPP3/calcineurin dephosphorylates TFEB (transcription factor EB) to trigger its nuclear translocation and the activation of macroautophagic/autophagic targets. However, the detailed molecular mechanism regulating TFEB activation remains poorly understood. Here, we highlighted the importance of SMURF1 (SMAD specific E3 ubiquitin protein ligase 1) in the activation of TFEB for lysosomal homeostasis. SMURF1 deficiency prevents the calcium-triggered ubiquitination of the catalytic subunit of PPP3/calcineurin in a manner consistent with defective autophagic degradation of damaged lysosomes. Mechanically, PPP3CB/CNA2 plays a bridging role in the recruitment of SMURF1 by LGALS3 (galectin 3) upon lysosome damage. Importantly, PPP3CB increases the dissociation of the N-terminal tail (NT) and C-terminal carbohydrate-recognition domain (CRD) of LGALS3, which may promote the formation of open conformers in a PPP3CB dephosphorylation activity-dependent manner. In addition, PPP3CB is ubiquitinated at lysine 146 by the recruited SMURF1 in response to intracellular calcium stimulation. The K63-linked ubiquitination of PPP3CB enhances the recruitment of TFEB. Moreover, TFEB directly interacts with both PPP3CB and the regulatory subunit PPP3R1 which facilitate the conformational correction of TFEB for its activation for the transcription of TFEB-targeted genes. Altogether, our results highlighted a critical mechanism for the regulation of PPP3/calcineurin activity via its ubiquitin ligase SMURF1 in response to lysosomal membrane damage, which may account for a potential target for the treatment of stress-related diseases.Abbreviation AID: autoinhibitory domain; ATG: autophagy related; CD: catalytic domain; CRD: carbohydrate-recognition domain; CsA: cyclosporin A; DMSO: dimethyl sulfoxide; ESCRT: endosomal sorting complexes required for transport; GSK3B: glycogen synthase kinase 3 beta; LAMP1: lysosomal associated membrane protein 1; LGALS3: galectin 3; LLOMe: L-leucyl-L-leucine methyl ester; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; ML-SA1: mucolipin synthetic agonist 1; MTORC1: mechanistic target of rapamycin kinase complex 1; NT: N-terminal tail; PPP3CB: protein phosphatase 3 catalytic subunit beta; PPP3R1: protein phosphatase 3 regulatory subunit B, alpha; SMURF1: SMAD specific E3 ubiquitin protein ligase 1; SQSTM1/p62: sequestosome 1; TFEB: transcription factor EB; VCP/p97: valosin containing protein; YWHA/14-3-3: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein.
elife-35316-v2.pdf
Creators: name: Pires, Paulo W.
name: Earley, Scott
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 111601 Cell Physiology
subject: FOS: Basic medicine
subject: 60603 Animal Physiology - Systems
subject: FOS: Biological sciences
subject: Biophysics
subject: Physiology

description: Hypoxia and ischemia are linked to oxidative stress, which can activate the oxidant-sensitive transient receptor potential ankyrin 1 (TRPA1) channel in cerebral artery endothelial cells, leading to vasodilation. We hypothesized that TRPA1 channels in endothelial cells are activated by hypoxia-derived reactive oxygen species, leading to cerebral artery dilation and reduced ischemic damage. Using isolated cerebral arteries expressing a Ca2+ biosensor in endothelial cells, we show that 4-hydroxynonenal and hypoxia increased TRPA1 activity, detected as TRPA1 sparklets. TRPA1 activity during hypoxia was blocked by antioxidants and by TRPA1 antagonism. Hypoxia caused dilation of cerebral arteries, which was disrupted by antioxidants, TRPA1 blockade and by endothelial cell-specific Trpa1 deletion (Trpa1 ecKO mice). Loss of TRPA1 channels in endothelial cells increased cerebral infarcts, whereas TRPA1 activation with cinnamaldehyde reduced infarct in wildtype, but not Trpa1 ecKO, mice. These data suggest that endothelial TRPA1 channels are sensors of hypoxia leading to vasodilation, thereby reducing ischemic damage.
MOESM5 of Auxin and cytokinin coordinate the dormancy and outgrowth of axillary bud in strawberry runner
Creators: name: Qiu, Yuting
name: Guan, Si
name: Wen, Chenjin
name: Li, Peng
name: Gao, Zhen
name: Chen, Xu
Publisher: name: figshare
Year: 2019
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 5: Figure S5. Replicates of DR5:GUS straining pictures.Â 6-BA treated FvDB have two different development types after release from dormancy. One is bud turnover, another is bud outgrowth. SAM: Shoot apical meristem; AM: Axillary meristem; VB: Vascular bundles; LF: Leaf; LP: Leaf primordium; RM: Root meristem
Constraints on non-Newtonian gravity from the Casimir force measurements between two crossed cylinders
Creators: name: Mostepanenko, V. M.
name: Novello, M.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Constraints on the Yukawa-type corrections to Newtonian gravitational law are obtained resulting from the measurement of the Casimir force between two crossed cylinders. The new constraints are stronger than those previously derived in the interaction range between 1.5 nm and 11 nm. The maximal strengthening in 300 times is achieved at 4.26 nm. Possible applications of the obtained results to the elementary particle physics are discussed.
description: An error in the text and in the figure had been corrected. To appear in Phys. Rev. D
Branching of Hydraulic Cracks in Gas or Oil Shale with Closed Natural Fractures: How to Master Permeability
Creators: name: Rahimi-Agham, Saeed
name: Chau, Viet-Tuan
name: Lee, Huynjin
name: Nguyen, Hoang
name: Li, Weixin
name: Karra, Satish
name: Rougier, Esteban
name: Viswanathan, Hari
name: Srinivasan, Gowri
name: Bazant, Zdenek P.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: While the hydraulic fracturing technology, aka fracking (or fraccing, frac), has become highly developed and astonishingly successful, a consistent formulation of the associated fracture mechanics that would not conflict with some observations is still unavailable. It is attempted here. Classical fracture mechanics, as well as the current commercial softwares, predict vertical cracks to propagate without branching from the perforations of the horizontal well casing, which are typically spaced at 10 m or more. However, to explain the gas production rate at the wellhead, the crack spacing would have to be only about 0.1 m, which would increase the overall gas permeability of shale mass about 10,000$\times$. This permeability increase has generally been attributed to a preexisting system of orthogonal natural cracks, whose spacing is about 0.1 m. But their average age is about 100 million years, and a recent analysis indicated that these cracks must have been completely closed by secondary creep of shale in less than a million years. Here it is considered that the tectonic events that produced the natural cracks in shale must have also created weak layers with nano- or micro-cracking damage. It is numerically demonstrated that a greatly enhanced permeability along the weak layers, with a greatly increased transverse Biot coefficient, must cause the fracking to engender lateral branching and the opening of hydraulic cracks along the weak layers, even if these cracks are initially almost closed. A finite element crack band model, based on recently developed anisotropic spherocylindrical microplane constitutive law, demonstrates these findings.
Towards an integrated wide approach for upstream field recovery
Creators: name: Ramjanee, Shakeel
Publisher: name: Imperial College London
Year: 2023

description: Integrated asset modelling is the modelling of an entire production facility comprising of both subsurface and surface elements. Historically, asset modelling has entailed discrete reservoir, well and facility models accompanied by silo discipline ownership. Adopting an integrated wide approach provides a holistic overview capturing the complex interactions between subcomponents thereby enabling the assessment of system constraints and identification of production optimisation opportunities. The objective of this research study is to develop a viable, representative alternative to the industry state of the art integrated asset modelling tool which can be deployed for short term surveillance and medium to long term field optimisation. A series of integrated asset frameworks were constructed using an industry integrated asset modelling tool; this served as a basis for the development of proxy models via traditional approaches such as the response surface methodology and regression to complex techniques such as Artificial Neural Networks, RS-HDMR and ALAMO. Functional relationships defining production and pressure responses were postulated for a gas field case and an oil field supplemented by water injection drive case. Global sensitivity analyses of selected input parameters were investigated to validate the postulated functional relationships and smoothing splines were deployed to alleviate instabilities in the pressure prediction outputs and improve the surrogate response. The optimisation of the surrogates via a constrained nonlinear optimisation framework in addition to gradient free optimisation techniques of neural networks yielded favourable results. Whilst the surrogates provided suitably accurate predictions, deviations were noted at late field life conditions suggesting suitability in early phases of the field development or production life cycle. The developed surrogate models are proven to predict production and pressure profiles within specified production windows at a fraction of the simulation time and computational efforts of the industry counterpart and can be extended to further field development types in future workflows.
Constraints on the Higgs boson properties from the effective potential
Creators: name: Quiros, M.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We review the constraints on Higgs boson properties from effective potential methods. In the Standard Model, the requirement of stability (or metastability) of the standard electroweak minimum puts an upper bound on the scale of new physics as a function of the Higgs mass. This upper bound is below the Planck scale if the Higgs weights $\simlt$ 130 GeV. In supersymmetric extensions of the Standard Model the former methods are useful to compute the Higgs mass spectrum, and couplings, after resumming higher loop effects. In particular, if the Higgs mass weights $\simgt$ 130 GeV, the minimal supersymmetric extension of the Standard Model will be ruled out, while its non-minimal supersymmetric extension containing singlets is only marginally allowed.
description: 33 pages, Latex + sprocl + psfig.sty. To appear in: Perspectives on Higgs Physics II, Ed. G.L. Kane, World Scientific, Singapore. One figure added
Calendula chrysanthemifolia Vent., Jard. Malmaison
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Calendula
Calendula chrysanthemifolia

description: 12. Calendula chrysanthemifolia Vent., Jard. Malmaison 1: tab. 56. 1804.
 Ξ Dimorphotheca chrysanthemifolia (Vent.) DC.
 Lectotypus (designated here): [SOUTH AFRICA]: Hort. Malmaison, Ventenat s.n. (G [G00341480]!; isolecto-: G [G00341479]!).
 Notes. – Two specimens of a single gathering have been located in Ventenat’s herbarium at G. It represents the plant cultivated in Empress Joséphine’s garden. The more complete collection is designated here as the lectotype.
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 100, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
The physical origin of reversible surface attachment in insects
Creators: name: Attipoe, Andrea
Publisher: name: Imperial College London
Year: 2023

description: Insects can attach themselves on surfaces under an impressive range of environmental conditions using adhesive pads. Earlier studies indicated the contact under the pad is mediated by a thin layer of liquid secretion, which could produce adhesive forces through capillary bridges and viscous effects. Previous work found another source of viscous dissipation in the viscoelastic properties of the pad. This lead to the formulation of two main supposed mechanisms of adhesion: "wet" and "dry" models, where temperature and rate, following distinct laws, act as crucial factors influencing these models. The wetting properties of the liquid secreted by the stick insect Carausius morosus were determined through interference reflection microscopy, and found to be weakly affected by temperature. Dewetting experiments indicated that the secretion’s viscosity is exponentially dependent on temperature. The storage and loss moduli of the pad were determined through creep experiments, and were found to be weakly influenced by temperature when compared to typical amorphous polymers. The resulting "wet" and "dry" models were compared to the adhesive forces produced by single pads during detachment at different temperatures and pulling rates. The measured forces were drastically affected by rate, while temperature had no significant effect. The adhesive performance of insect pads can thus not be explained by "wet" models, due to the inconsistencies of capillary forces with rate dependence, and viscous forces with weak temperature influence. On the other hand, the rate dependence of the energy required to break adhesive bonds in viscoelastic fracture corresponded with the measured pull-off forces, and the weak temperature dependence of the viscoelastic properties of the pad was consistent with the similar performance of the pads. Hence, I argue that fracture mechanics theories of viscous dissipation offer a viable answer to the question of reversible surface attachment in insects.
Atractylenolide I inhibits angiogenesis and reverses sunitinib resistance in clear cell renal cell carcinoma through ATP6V0D2-mediated autophagic degradation of EPAS1/HIF2α
Creators: name: Li, Qinyu
name: Zeng, Kai
name: Chen, Qian
name: Han, Chenglin
name: Wang, Xi
name: Li, Beining
name: Miao, Jianping
name: Zheng, Bolong
name: Liu, Jihong
name: Yuan, Xianglin
name: Liu, Bo
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Clear cell renal cell carcinoma (ccRCC) is tightly associated with VHL (von Hippel-Lindau tumor suppressor) mutation and dysregulated angiogenesis. Accumulating evidence indicates that antiangiogenic treatment abolishing tumor angiogenesis can achieve longer disease-free survival in patients with ccRCC. Atractylenolide I (ATL-I) is one of the main active compounds in Atractylodes macrocephala root extract and exhibits various pharmacological effects, including anti-inflammatory and antitumor effects. In this study, we revealed the potent antitumor activity of ATL-I in ccRCC. ATL-I exhibited robust antiangiogenic capacity by inhibiting EPAS1/HIF2α-mediated VEGFA production in VHL-deficient ccRCC, and it promoted autophagic degradation of EPAS1 by upregulating the ATPase subunit ATP6V0D2 (ATPase H+ transporting V0 subunit d2) to increase lysosomal function and facilitated fusion between autophagosomes and lysosomes. Mechanistically, ATP6V0D2 directly bound to RAB7 and VPS41 and promoted the RAB7-HOPS interaction, facilitating SNARE complex assembly and autophagosome-lysosome fusion. Moreover, ATP6V0D2 promoted autolysosome degradation by increasing the acidification and activity of lysosomes during the later stages of macroautophagy/autophagy. Additionally, we found that ATL-I could decrease the level of EPAS1, which was upregulated in sunitinib-resistant cells, thus reversing sunitinib resistance. Collectively, our findings demonstrate that ATL-I is a robust antiangiogenic and antitumor lead compound with potential clinical application for ccRCC therapy. Abbreviations: ATL-I: atractylenolide I; ATP6V0D2: ATPase H+ transporting V0 subunit d2; CAM: chick chorioallantoic membrane; ccRCC: clear cell renal cell carcinoma; CTSB: cathepsin B; CTSD: cathepsin D; GO: Gene Ontology; HIF-1: HIF1A-ARNT heterodimer; HOPS: homotypic fusion and protein sorting; KDR/VEGFR: kinase insert domain receptor; KEGG: Kyoto Encyclopedia of Genes and Genomes; RCC: renal cell carcinoma; SNARE: soluble N-ethylmaleimide-sensitive factor attachment protein receptor; TCGA: The Cancer Genome Atlas; TEM: transmission electron microscopy; TKI: tyrosine kinase inhibitor; V-ATPase: vacuolar-type H±translocating ATPase; VEGF: vascular endothelial growth factor; VHL: von Hippel-Lindau tumor suppressor.
A hyperspectral optical surgical tool for circumferential resection margin assessment in gastrointestinal cancer surgery
Creators: name: Gkouzionis, Ioannis
Publisher: name: Imperial College London
Year: 2023

description: Gastrointestinal (GI) cancers represent a significant contributor to the global cancer burden. Surgery typically constitutes the primary therapeutic approach for GI malignancies, with the primary objective of maximising tumour tissue excision while maintaining an adequate margin of healthy tissue (clear margin) surrounding the tumour. The presence of a clear margin, devoid of cancer cells, is essential in minimising the risk of cancer recurrence. Accurate mapping of tumour margins is crucial for achieving a negative resection margin. Local recurrence following surgical resection significantly impacts the overall survival and quality of life for patients with GI cancer. In this thesis, we have investigated diffuse reflectance spectroscopy (DRS) technology, combined with artificial intelligence, to develop a pioneering optical surgical tool aimed at improving the identification of resection margins in GI cancer surgery. The primary goal is to enhance the precision and reliability of tumour margin demarcation, thereby increasing the likelihood of complete tumour removal with clear margins, which is critical for reducing the risk of cancer recurrence and improving patient survival and quality of life. This work presents a two-fold unique contribution towards the optimal resection margins assessment in GI surgery. Firstly, by introducing a novel exploratory data analysis and classification routine employing deep neural networks to distinguish healthy and malignant tissues based on spectral measurements, and secondly, by developing a deep learning model to facilitate the detection and tracking of the DRS fibre probe during surgery. This approach represents a significant advancement over previous studies by providing a comprehensive analysis using machine learning techniques for GI cancer discrimination and addressing the challenge of probe detection and tracking for the first time. Through validation in clinical settings, this work aims to advance the standard of care in GI cancer surgery, demonstrating the potential of DRS technology and AI to improve surgical outcomes.
"Superconductor-Insulator transition" in a single Josephson junction
Creators: name: Penttila, J. S.
name: Parts, U.
name: Hakonen, P. J.
name: Paalanen, M. A.
name: Sonin, E. B.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: VI-curves of resistively shunted single Josephson junctions with different capacitances and tunneling resistances are found to display a crossover between two types of VI-curves: one without and another with a resistance bump (negative second derivative) at zero-bias. The crossover corresponds to the dissipative phase transition (superconductor-insulator transition) at which macroscopic quantum tunneling delocalizes the Josephson phase and destroys superconductivity. Our measured phase diagram does not agree with the diagram predicted by the original theory, but does coincide with a theory that takes into account the accuracy of voltage measurements and thermal fluctuations.
description: 4 pages, 4 figures
Baryogenesis via lepton number violation in Anti-GUT model
Creators: name: Nielsen, H. B.
name: Takanishi, Y.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the baryogenesis via lepton number violation in the model of Anti-GUT. The origin of the baryogenesis is the existence of right-handed Majorana neutrinos which decay in a C, CP and lepton number violation way. The baryon number asymmetry is calculated in the extended Anti-GUT model which is only able to predict order of magnitude-wise. We predicted baryon number to entropy ratio, Y_B=1.46{+5.87\atop-1.17}\times10^{-11}, and this result agrees with experimental values very well.
description: 14 pages, 3 figures, Latex2e;v2 sec.3 and 4 changed, minor corrected
Optimal coloured perceptrons
Creators: name: Bolle', D.
name: Kozlowski, P.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Ashkin-Teller type perceptron models are introduced. Their maximal capacity per number of couplings is calculated within a first-step replica-symmetry-breaking Gardner approach. The results are compared with extensive numerical simulations using several algorithms.
description: 8 pages in Latex with 2 eps figures, RSB1 calculations has been added
MOESM6 of Auxin and cytokinin coordinate the dormancy and outgrowth of axillary bud in strawberry runner
Creators: name: Qiu, Yuting
name: Guan, Si
name: Wen, Chenjin
name: Li, Peng
name: Gao, Zhen
name: Chen, Xu
Publisher: name: figshare
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Additional file 6: Table S1. Runner pattern in different species of Fragaria. Table S2. Summary of transcriptome sequencing
Towards personalised medicine - developing a 3D leukaemia biomimicry
Creators: name: Salgado Soares Dos Santos, Joana
Publisher: name: Imperial College London
Year: 2022

description: Leukaemia is a form of cancer that affects cells of the haematopoietic lineage. Acute myeloid leukaemia (AML) and chronic lymphocytic leukaemia (CLL) are the two most common types, accounting for 31% and 38% of all leukaemia diagnoses in the United Kingdom. The study of leukaemia has been traditionally conducted in two-dimensional (2D) cultures or resorting to animal models, both systems failing to recapitulate the physiological parameters of the disease. A three-dimensional (3D) bone marrow model comprised of polyurethane (PU) scaffolds coated with Collagen I has been shown to allow the culture of leukaemic cell lines, showing potential towards the culture of primary cells. In this thesis, this 3D model was tailored to the culture of primary bone marrow (BM) and peripheral blood (PB) cells of patients with leukaemia, using serum-free cytokine-free conditions and enabling a long-term culture (>28 days). Scaffold dimensions, geometry, cell seeding methods, extraction methods, coating proteins and storage protocols were studied and optimised. The study of AML in this platform allowed the xenofree culture of PB and BM cells for up to 6 weeks, maintaining >80% viability, 30 days longer than the previously reported primary AML culture. The long-term viable cultures allowed the study of population dynamics through flow cytometry, measurement of cell expansion and delivery of chemotherapy, highlighting higher susceptibility of primary cells to drugs. The study of CLL allowed for long-term cultures of up to 8 weeks of cells derived from PB and BM, demonstrating that 3D and serum-free conditions reduced CLL cell apoptosis in vitro, allowing the delivery of a novel BCL2 inhibitor. This is the first long-term serum-free, cytokine-free and feeder-cell free culture to be reported. In summary, this thesis reports the long-term xenofree study of primary leukaemia in a PU scaffold, allowing the study of population dynamics and drug delivery.
Casearia ulmifolia Vent., Choix Pl.
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Salicaceae
Casearia
Casearia ulmifolia

description: 13. Casearia ulmifolia Vahl ex Vent., Choix Pl.: sub tab. 46. 1808.
 Lectotypus (first step designated by Sleumer, 1980: 324; second step designated here): TRINIDAD: 1778, Ryan 20 (C [C 10012565] image seen; isolecto-: BM [BM000624343] image seen, BR [BR0000005104826] image seen, C [C 10012566, C 10012567, C 10012568, C 10012569, C 10012570, C 10012571] images seen, G [G00364133]!, L [L0010781] image seen, P-JU n° 16215 [P00678826]!).
 Notes. – Ventenat validated Vahl’s name by publishing a few comparative leaf characters: “[bords de feuille] finement dentés en scie”. Sleumer (1980: 324) correctly considered the type as being held at C. His implicit lectotypification needs a second step designation as seven sheets exist at C. In their revision of the Casearia ulmifolia complex, Marquete & Mansano (2012: 201) failed to properly designate a single sheet at C as the lectotype. We designate the most complete sheet in C as the lectotype. Several isolectotypes are known, among them one in Ventenat’s herbarium. We are not in agreement with previous authors (Sleumer, 1980; Marquete & Mansano, 2012) and do not consider the collection in G-DC [G00476917] as elements of original material.
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 100, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
Casuarina distyla Vent., Descr. Pl. Nouv.
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fagales
Casuarinaceae
Casuarina
Casuarina distyla

description: 14. Casuarina distyla Vent., Descr. Pl. Nouv.: tab. 62. 1802.
 Ξ Allocasuarina distyla (Vent.) L.A.S. Johnson
 Typus: [AUSTRALIA]: Hort. Cels, Ventenat s.n. (holo-: G [G00341454]!; iso-: NSW [NSW62357] image seen).
 Notes. – Johnson (1992: 75) transferred Casuarina distyla to his new genus Allocasuarina L.A.S. Johnson. The author designated the collection at G from Cels’s garden as the lectotype.Only one collection is extant inVentenat’s herbarium and should therefore be considered as the holotype.A clastotype is present in NSW and should be considered as the isotype.The two other collections mentioned by Johnson (1992: 75) in K [K000872501] (Herb. Forsyth. purchased 1835) and P [P00735055] (“donné par Bonpland en 1835”) have been very likely collected later in Cels’s garden and are here not considered as isotypes. The provenance of the plant has been recorded as “Cap de Diemen” in Tasmania but is clearly from New South Wales (Johnson, 1992).
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 100, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
Elastic constant dishomogeneity and $Q^2$ dependence of the broadening of the dynamical structure factor in disordered systems
Creators: name: Montagna, M.
name: Ruocco, G.
name: Viliani, G.
name: Di Leonardo, R.
name: Dusi, R.
name: Monaco, G.
name: Sampoli, M.
name: Scopigno, T.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We propose an explanation for the quadratic dependence on the momentum $Q$, of the broadening of the acoustic excitation peak recently found in the study of the dynamic structure factor of many real and simulated glasses. We ascribe the observed $Q^2$ law to the spatial fluctuations of the local wavelength of the collective vibrational modes, in turn produced by the dishomegeneity of the inter-particle elastic constants. This explanation is analitically shown to hold for 1-dimensional disordered chains and satisfatorily numerically tested in both 1 and 3 dimensions.
description: 4 pages, RevTeX, 5 postscript figures
Smart Window Structures Based on Highly Conductive, Transparent Metal Nanomeshes and Thermochromic Perovskite Films
Creators: name: Wu, Shang-Hsuan
name: Cossio, Gabriel
name: Braun, Benjamin
name: Wu, Frances Camille M.
name: Yu, Edward T.
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: nanosphere lithography
transparent conductive electrodes
metal mesh
thermochromic perovskite
smart windows

description: Smart windows are energy-efficient windows whose optical transparency can be switched between highly transparent and opaque states in response to incident solar illumination. Transparent and conductive metal nanomesh (NM) films are promising candidates for thermochromic smart windows due to their excellent thermal conductivity, high optical transparency at near infrared wavelengths, and outstanding stability. In this study, ZnO/Au/Al2O3 NM films with periodicities of 200 nm and 370 nm are reported. The ZnO/Au/Al2O3 NM film with a 370-nm periodicity exhibits a transmittance over 90% at 550 nm and sheet resistance lower than 20 Ω/sq. Based on a standard figure of merit, this structure outperforms current state-of-the-art nanomesh films. We also demonstrate the integration of ZnO/Au/Al2O3 NM films into a thermochromic perovskite (TC-PVK) smart window. The transparency of the smart window structure is manipulated by transient resistive heating to trigger the thermochromic transition to the opaque state, which can be then maintained solely by 1-sun, AM 1.5 G illumination. This climate-adaptive, low power-activated, and fast-switching smart window structure opens new pathways towards its practical application in the real world.
Human pose, posture, and shape estimation for mobile robots
Creators: name: Henning, Dorian
Publisher: name: Imperial College London
Year: 2023

description: The increasing deployment of autonomous systems in populated environments requires robots to possess a deep understanding of humans in their surroundings. It would be particularly desirable if this understanding could be achieved automatically through the use of vision-based sensing, and is integrated into existing robotic state estimation frameworks to leverage synergies between the two approaches. However, current robotic state estimation systems typically do not incorporate human states and their estimation into their frameworks or representation. Although existing methods in human state estimation achieve high accuracy, they often lack computational efficiency and fail to produce a globally consistent and feasible estimation in line with the observed scene. To achieve human-robot understanding and facilitate higher-level interaction, autonomous systems need to integrate human state estimation as an integral part of scene understanding. This thesis addresses these challenges by developing methods to estimate human states, including posture, shape, and relative position with respect to the observing robotic system, using different sensor modalities in standard SLAM frameworks. Additionally, this thesis proposes a learned human motion model to improve the accuracy of human state estimation and enable monocular, scale-aware camera tracking. Finally, a joint formulation of human and robotic state estimation is presented, demonstrating its potential to improve accuracy and performance for both sides. These contributions have the potential to enable robotic systems to understand humans in their surroundings and facilitate safe and effective human-robot interaction.
B-Script: Transcript-based B-roll Video Editing with Recommendations
Creators: name: Huber, Bernd
name: Shin, Hijung Valentina
name: Russell, Bryan
name: Wang, Oliver
name: Mysore, Gautham J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Graphics (cs.GR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: H.5.2

description: In video production, inserting B-roll is a widely used technique to enrich the story and make a video more engaging. However, determining the right content and positions of B-roll and actually inserting it within the main footage can be challenging, and novice producers often struggle to get both timing and content right. We present B-Script, a system that supports B-roll video editing via interactive transcripts. B-Script has a built-in recommendation system trained on expert-annotated data, recommending users B-roll position and content. To evaluate the system, we conducted a within-subject user study with 110 participants, and compared three interface variations: a timeline-based editor, a transcript-based editor, and a transcript-based editor with recommendations. Users found it easier and were faster to insert B-roll using the transcript-based interface, and they created more engaging videos when recommendations were provided.
description: 11 pages, 10 figures, CHI 2019
Scaling in the Integer Quantum Hall Effect: interactions and low magnetic fields
Creators: name: Huckestein, Bodo
name: Backhaus, Michael
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Recent developments in the scaling theory of the integer quantum Hall effect are discussed. In particular, the influence of electron-electron interactions on the critical behavior are studied. It is further argued that recent experiments on the disappearance of the quantum Hall effect at low magnetic fields support rather than disprove the scaling theory, when interpreted properly.
description: 13 pages, invited talk at DPG spring meeting, Regensburg, March 2000, to appear in Advances in Solid State Physics, ed. B. Kramer