cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dynamics of transcription factor binding site evolution
Creators: name: Tuğrul, Murat
name: Paixão, Tiago
name: Barton, Nicholas H.
name: Tkačik, Gašper
Publisher: name: arXiv
Year: 2015
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: Evolution of gene regulation is crucial for our understanding of the phenotypic differences between species, populations and individuals. Sequence-specific binding of transcription factors to the regulatory regions on the DNA is a key regulatory mechanism that determines gene expression and hence heritable phenotypic variation. We use a biophysical model for directional selection on gene expression to estimate the rates of gain and loss of transcription factor binding sites (TFBS) in finite populations under both point and insertion/deletion mutations. Our results show that these rates are typically slow for a single TFBS in an isolated DNA region, unless the selection is extremely strong. These rates decrease drastically with increasing TFBS length or increasingly specific protein-DNA interactions, making the evolution of sites longer than ~10 bp unlikely on typical eukaryotic speciation timescales. Similarly, evolution converges to the stationary distribution of binding sequences very slowly, making the equilibrium assumption questionable. The availability of longer regulatory sequences in which multiple binding sites can evolve simultaneously, the presence of "pre-sites" or partially decayed old sites in the initial sequence, and biophysical cooperativity between transcription factors, can all facilitate gain of TFBS and reconcile theoretical calculations with timescales inferred from comparative genetics.
description: 28 pages, 15 figures
Thailand's Policy Response to HIV Among Sex Workers: A Look Through a Gendered Lens
Creators: name: Nandi, Anwesha
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: The Thai response to HIV/AIDS is often applauded as a model of success. Targeted at female sex workers, the 100% Condom Program was incredibly effective at curbing the HIV epidemic during the 1980s and early 1990s. However, little research has been done since to examine the impact of policies and interventions on HIV/AIDS among sex workers. To address the gaps in existing research and HIV/AIDS policies, I examine the relationship between gender of sex worker and HIV/AIDS policies. I utilize existing knowledge of Thai policymaking, norms about gender and sexuality, and HIV to create a social construction theoretical framework about sex workers. In my analysis, I examine the ways that national HIV/AIDS policy reports developed by the Thai Ministry of Public Health discuss male, female, and transgender sex workers. To add another dimension of analysis, I build case study analyses of Bangkok and Chiang Mai using Thai news media that discuss HIV and sex workers. 

By using both these approaches, I uncover the policy priorities and rhetoric around sex workers both in the policymaking landscape as well as how those policies are translated into the public eye and perceptions. I find that female sex workers, both historically and currently, are the focus of HIV policies and interventions. I also find that male and transgender sex workers are surveyed inconsistently in policy, and are framed differently to female sex workers. I highlight the discrepancies between media coverage and policy coverage of HIV in sex workers. My thesis concludes with recommendations for the Ministry of Public Health as well as implications for the gendered differences in discussing HIV/AIDS among sex workers.
Tachysurus fulvidraco isolate:Tf-2017 Genome sequencing and assembly
Creators: name: BGI
Publisher: name: CNGB
Year: 2018
Subjects: Genome sequencing and assembly
Monoisolate

description: The yellow catfish, Pelteobagrus fulvidraco, (Richardson, 1846; NCBI TaxonomyID: 1234273; Fishbase ID: 28052) is a teleost fish belonging to the order Siluriformes
Strategi Inovatif Pengolahan Dimsum Ikan Patin Guna Pemberdayaan UMKM Desa Katipo Pura
Creators: name: Zulkifli, Noval Kurniawan, Elden Chaesa Sihombing, Tiara Kencana Putri Deza, Jessy Fitrianti, Rahmaini Rahmaini, Onni Fanya Nabilah, Sry Rohayu, Desi Yuliana Fitri, Azra Andiwinata, Christian Ebenezer Banjarnahor
Publisher: name: Zenodo
Year: 2024

description: Kuliah Kerja Nyata merupakan salah satu bentuk kegiatan ekstrakurikuler berupa pengabdian yang dilaksanakan dengan periode dan daerah tertentu atas dasar memadukan tridharma perguruan tinggi. Pengabdian mahasiswa dilakukan melalui kolaborasi antara perguruan tinggi Universitas Riau dan masyarakat Desa Katipo Pura, Kecamatan Peranap, Kabupaten Indragiri Hulu. Mahasiswa sebagai agen pembawa perubahan, membantu mengembangkan potensi SDA dan SDM yang ada pada Desa Katipo Pura, salah satunya dalam sektor pemberdayaan UMKM. Desa Katipo Pura merupakan desa dipinggir sungai, sehingga banyak masyarakat yang berprofesi sebagai nelayan dan pedagang ikan, namun sulit mendapatkan koneksi internet yang baik sehingga terlambat dalam mendapatkan informasi terbaru. Oleh karena itu, tujuan dilakukannya kegiatan pengabdian ini salah satunya yaitu sosialisasi Dimsum berbahan dasar Ikan Patin. Pengabdian ini bertujuan untuk memberikan ilmu dan inovasi baru kepada masyarakat Desa Katipo Pura dalam mengolah potensi SDA guna meningkatkan UMKM Desa mengenai usaha makanan yang tidak hanya lezat dan trending namun juga sehat. Hasil dari pengabdian ini membuktikan bahwa ternyata masyarakat bersemangat dalam meningkatkan UMKM, namun mereka membutuhkan ilmu baru dalam bentruk insfrastuktur yang baik seperti koneksi internet yang lancar agar menjadi desa yang maju.
Clostridioides difficile strain:not collected | isolate:not collected Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2018
Subjects: genome sequencing
Monoisolate

description: Genetic character of three ST11 Clostridium difficile isolates with different RTs: tcdC deletion is not the unique feature of RT078 indicated by complete whole genome sequencing
PDEδ interference impedes the proliferation and survival of oncogenic KRas expressing human cancer cell lines
Creators: name: Klein, Christian H.
Publisher: name: Technische Universität Dortmund
Year: 2018
Subjects: subject: KRas
subject: Colorectal cancer
subject: PDEδ
subject: Proliferation
subject: 570
subject: 540
subject: Krebs
subject: Medizin

description: Ras proteins, most notably isoform KRas4B are frequently mutated oncogenes in numerous human cancers and associated with poor prognosis. Despite ambitious research affords since the discovery of Ras proteins as human oncogenes in 1982, no pharmacological therapy approach reached the clinic yet and Ras is still viewed as “undruggable” protein. For signal propagation, Ras proteins have to be localized at the plasma membrane. Enrichment there is facilitated by spatial cycles that utilize the prenyl binding protein PDEδ as solubilizing factor. Thus, instead of targeting Ras proteins directly, interference with its spatial organization by targeting PDEδ was studied as promising alternative. First generations of small molecule inhibitors of PDEδ were reported to selectively affect proliferation of oncogenic KRas-dependent human pancreatic ductal adenocarcinoma cell lines. Here, we characterize the activity of a new small molecule inhibitor chemotype called Deltasonamide in cells. We show that Deltasonamide administration leads to a depletion of KRas from the plasma membrane and report enhanced anti-proliferative effects of the high affinity inhibitor in oncogenic KRas-dependent human pancreatic ductal adenocarcinoma cell lines, for the first time at sub-micromolar concentrations. Furthermore, we demonstrate that PDEδ inhibition is also an applicable tool to interfere with aberrant KRas signaling in human colorectal cancer cell lines. Both PDEδ knock down and small molecule inhibition selectively reduced proliferation and viability of colorectal cancer cell lines harboring oncogenic KRas mutations, whereas cell lines expressing only wild type KRas were not affected by interference with PDEδ. Moreover, we report an interdependence of oncogenic KRas activity and PDEδ’s solubilizing function that is manifested in the correlation of both proteins within the cell lines and well reflected in the distinct survivability after PDEδ interference. Together, our results show that PDEδ is a valid therapeutic target in both pancreatic ductal adenocarcinoma and colorectal cancer harboring oncogenic KRas mutations.
Fiber fuse behavior veiled in its strong light emission
Creators: name: TODOROKI, Shin-ichi
Publisher: name: National Institute for Materials Science
Year: 2023
Subjects: fiber fuse
optical fiber
light-induced damage
self-pumping

description: Fiber fuse was discovered in 1987 and now poses a dilemma to the optical
communication industry as a result of the expected saturation of
communication capacity and the potential risks of high-power light
manipulation. I found that the periodic void train left behind is the
record of its energy state that can be modified by some external
conditions including the pump power, the coating condition of the
cladding surface, and the geometry of optical paths for re-absorption of
its emission. Thus, the interval of the voids increases in a segment
where re-absorption occurred. In addition, I found a modification delay
of the void interval, namely sub-millimeters, compared with the coating
change along the fiber. This is due to the high viscosity of the silica
melt surrounding the bright spot.
Diving Deep into Sentiment: Understanding Fine-tuned CNNs for Visual Sentiment Prediction
Creators: name: Campos, Victor
name: Salvador, Amaia
name: Jou, Brendan
name: Giró-i-Nieto, Xavier
Publisher: name: arXiv
Year: 2015
Subjects: subject: Multimedia (cs.MM)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences
subject: I.2.10; H.1.2

description: Visual media are powerful means of expressing emotions and sentiments. The constant generation of new content in social networks highlights the need of automated visual sentiment analysis tools. While Convolutional Neural Networks (CNNs) have established a new state-of-the-art in several vision problems, their application to the task of sentiment analysis is mostly unexplored and there are few studies regarding how to design CNNs for this purpose. In this work, we study the suitability of fine-tuning a CNN for visual sentiment prediction as well as explore performance boosting techniques within this deep learning setting. Finally, we provide a deep-dive analysis into a benchmark, state-of-the-art network architecture to gain insight about how to design patterns for CNNs on the task of visual sentiment prediction.
description: Preprint of the paper accepted at the 1st Workshop on Affect and Sentiment in Multimedia (ASM), in ACM MultiMedia 2015. Brisbane, Australia
研究者から見たMendeley
Creators: name: 轟 眞市
Publisher: name: National Institute for Materials Science
Year: 2023
Subjects: Mendeley
readership statistics
ORCID
ImpactStory

description: ユーザ目線では「クラウドによる文献管理」と見えるMendeleyは、アプリケーション側からみれば「文献利用度データベース」となり、そのデータはMendeley APIとして公開されている。これは、研究者がMendeleyを利用していなくても、自分の論文の読まれ方が公開されていることを意味している。被引用数よりも早期に反響が可視化されるサービスを紹介する。
The genomes of early-branching streptophyte green algae shed light on the dawn of plant terrestrialization
Creators: name: BGI
Publisher: name: CNGB
Year: 2018
Subjects: genome sequencing and assembly
Multispecies

description: Streptophyte algae has been reported to play a crucial role in transition from aquatic algae to embryophytes during the evolution of life. Here, we generate two draft genomes of the early-branching Streptophyte algae, Mesostigma viride and Chlorokybus atmophyticus.
Penalized regression for predicting phenotypes in the Collaborative Cross
Creators: name: Chen, Jinyu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: The Collaborative Cross (CC) are a set of recombinant inbred laboratory mouse strains whose genotype data are designed to have a natural grouping structure. Given a set of quantitative phenotype data of a subset of genotyped CC strains, we want to train a model that can predict phenotype values of the CC strains for which the data for this phenotype is missing. In genetic studies, linear models are generally used to relate the genotypes to the phenotypes. However, the solution to a simple linear regression with high dimensional genomic data is often undefined. In this case, penalized regressions are applied to eliminate variables with little predictive strength. We designed a series of cross-validated tests to explore the prediction performances of different penalized regression approaches on the CC data. We found that lasso and the group lasso lead to lower mean cross-validated sum of squared errors when used with the optimal tuning parameters. However, in most cases, both methods failed to find a set of predictors that significantly outperforms the intercept-only model.
CLINICAL-DIAGNOSTIC FEATURES AND COMPLEXITY OF TREATMENT IN THE COMORBID COURSE OF PULMONARY TUBERCULOSIS AND MALIGNANT TUMORS
Creators: name: Iskandarova, M.
name: Usmonov, X.
Publisher: name: Zenodo
Year: 2024

description: An oncologist diagnoses tuberculosis and oncological diseases, each clinician has a clear form of the disease development, an epidemiologist treats it and treats it adequately.
Nursing Students' Experience With, Knowledge, and Perceptions of E-Cigarettes
Creators: name: Roma, Phillip
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Nurses and other healthcare providers play key roles in screening and smoking cessation for their patients (VanDevanter et al., 2016). As e-cigarette use increases rapidly among U.S. adolescents and young adults, nursing students are likely to have had experience with e-cigarettes. The purpose of this study is to investigate undergraduate nursing students' experience with, knowledge, and perceptions of e-cigarettes as well as assess nursing students’ attitudes surrounding e-cigarette use screening and patient education. An anonymous, 22-item Qualtrics survey was developed and distributed to 416 undergraduate nursing students at the University of North Carolina at Chapel Hill. The survey asked participants a variety of questions assessing their e-cigarette use, knowledge, perceptions, and opinions regarding screening for e-cigarette use in healthcare settings. Among the 416 eligible nursing students, 83 (20.0%) completed the survey. Of the 83 survey respondents, 43.4% reported ever using e-cigarettes, and 12% reported e-cigarette use within the past 30 days. Likert scores revealed that a majority of nursing students perceived e-cigarettes as addictive, harmful, and viewed them as an incoming public health crisis. A majority of nursing students also agreed that healthcare providers should screen for and warn all patients about the risks of e-cigarette use. Student responses to two open-ended questions offered insights into the students’ perceived barriers and facilitators to e-cigarette use screening. These findings highlight the potential for e-cigarette use screening in the healthcare setting and the importance of preparing future nurses to provide effective counseling to their patients.
Lojasiewicz-Simon gradient inequalities for analytic and Morse-Bott functions on Banach spaces
Creators: name: Feehan, Paul M. N.
name: Maridakis, Manousos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 58E20, secondary 37D15

description: We prove several abstract versions of the Lojasiewicz-Simon gradient inequality for an analytic functional on a Banach space that generalize previous abstract versions of this inequality, weakening their hypotheses and, in particular, the well-known infinite-dimensional version of the gradient inequality due to Lojasiewicz proved by Simon (1983). We also prove that the optimal exponent of the Lojasiewicz-Simon gradient inequality is obtained when the functional is Morse-Bott, improving on similar results due to Chill (2003, 2006), Haraux and Jendoubi (2007), and Simon (1996). In our article arXiv:1903.01953, we apply our abstract Lojasiewicz-Simon gradient inequalities to prove a Lojasiewicz-Simon gradient inequalities for the harmonic map energy functional using Sobolev spaces which impose minimal regularity requirements on maps between closed, Riemannian manifolds. Those inequalities for the harmonic map energy functional generalize those of Kwon (2002), Liu and Yang (2010), Simon (1983, 1985), and Topping (1997). In our monograph arXiv:1510.03815, we prove Lojasiewicz--Simon gradient inequalities for coupled Yang--Mills energy functions using Sobolev spaces which impose minimal regularity requirements on pairs of connections and sections. Those inequalities generalize that of the pure Yang--Mills energy function due to the first author (Theorems 23.1 and 23.17 in arXiv:1409.1525) for base manifolds of arbitrary dimension and due to Rade (1992) for dimensions two and three.
description: 31 pages, incorporating final galley proof corrections. To appear in Journal fur die reine und angewandte Mathematik (Crelle's Journal)
The Influence of Stress and Concussion History on Cognitive Efficiency
Creators: name: Barron, Emily
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Impaired working memory is common following concussion and neurophysiological deficits are known to outlast clinical measure normalization. This disconnect is thought to be the result of compensatory neural resource utilization which suggests cognitive inefficiency. Cognitive pupillary responses are established psychophysiological measures that reflect global neural resource utilization in response to cognitive demands—which may help inform both clinical and physiological aspects of working memory. Little is known about the influence of chronic stress on these clinical and physiological measures in healthy individuals. Therefore, the purpose of this study was to examine the mediation effects of self-perceived chronic stress and concussion history on task performance and pupillary responses during a backwards overload digit-span task, in healthy individuals. Forty participants were included [mean age = 20.85 +/- 2.1 years, 50% male, 42.5% with history of concussion]. In both the pupillary response and task performance models, there was a significant effect of sequence-length (F[1,398]=8.30, p=0.004) and (F[1,398]=263.15, p=<0.0001), respectively. Specifically, greater sequence-lengths exhibited lower task performance and larger mean pupillary responses (i.e., greater neural resource utilization) until working memory capacity was met at which pupillary responses began to reduce. Concussion history, chronic stress, and the interaction between concussion history and chronic stress were not significant in either model. These findings support the sensitivity of pupillary response to cognitive load and working memory capacity during an overload digit-span task beyond performance-based measures alone. Our assessment for cognitive efficiency using VR and eye tracking technology may have implications for clinical practice and future cognitive interventions, specifically in concussed populations.
Helicobacter pylori strain:Hpbs2 Genome sequencing and assembly
Creators: name: BGI
Publisher: name: CNGB
Year: 2019
Subjects: genome sequencing and assembly
Monoisolate

description: Helicobacter pylori CompleteGenome Sequencing. The Hpbs2 strain comes from the gastric mucosa of patients with chronic gastritis, it is Helicobacter pylori with resistant to claymycin, metronidazole, levofloxacin.
Classical extension of quantum-correlated separable states
Creators: name: Bellomo, Guido
name: Plastino, Angelo
name: Plastino, Angel R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Li and Luo [Phys. Rev. A 78 (2008), 024303] discovered a remarkable relation between discord and entanglement. It establishes that all separable states can be obtained via reduction of a classicaly-correlated state "living" in a space of larger dimension. Starting from this result, we discuss here an optimal classical extension of separable states and explore this notion for low-dimensional systems. We find that the larger the dimension of the classical extension, the larger the discord in the original separable state. Further, we analyze separable states of maximum discord of two qubits, and their associated classical extensions.
description: 13 pages, 5 figures. To be published in Int. J. Quantum Info
$S_3$ symmetry and the quark mixing matrix
Creators: name: Das, Dipankar
name: Dey, Ujjal Kumar
name: Pal, Palash B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We impose an $S_3$ symmetry on the quark fields under which two of three quarks transform like a doublet and the remaining one as singlet, and use a scalar sector with the same structure of $SU(2)$ doublets. After gauge symmetry breaking, a $\mathbb{Z}_2$ subgroup of the $S_3$ remains unbroken. We show that this unbroken subgroup can explain the approximate block structure of the CKM matrix. By allowing soft breaking of the $S_3$ symmetry in the scalar sector, we show that one can generate the small elements, of quadratic or higher order in the Wolfenstein parametrization of the CKM matrix. We also predict the existence of exotic new scalars, with unconventional decay properties, which can be used to test our model experimentally.
description: 7 pages, no figure
Helicobacter pylori strain:Hpbs3 Genome sequencing and assembly
Creators: name: BGI
Publisher: name: CNGB
Year: 2019
Subjects: genome sequencing and assembly
Monoisolate

description: Helicobacter pylori CompleteGenome Sequencing. The Hpbs3 strain comes from the gastric mucosa of patients with chronic gastritis, it is Helicobacter pylori with resistant to claymycin.
Construction and Characterization of an NMR Spectrometer Operating at Earth's Magnetic Field
Creators: name: Mesits, Boris
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Spin is a property of many nuclei which can be exploited for imaging and spectroscopy with nuclear magnetic resonance (NMR) studies. While most medical applications of NMR require large magnets to create the resonance phenomenon, the natural magnetic field of the Earth can also serve the same purpose. Although spectral resolution is lower due to the relatively weak field of the Earth, the continuous presence of this natural field provides an opportunity for easy application of NMR techniques in the field. 

To access this opportunity, we build and characterize the performance of a low-cost, portable NMR spectrometer, based on the design published by Michal (2010). A standard microcontroller, fed with open-source pulse programming software from a typical laptop, operates the experiment's coil, removing the need for an expensive proprietary controller. We find that the system, despite its simplicity, is susceptible to unwanted feedback-driven oscillations in the output signal, which depends sensitively on the layout of the electronic components. We show that these oscillations may be due both to inductive coupling of ground wires to amplifier outputs, and to signal-ground coupling inherent to the microcontroller. After removing the feedback-driven oscillations, we demonstrate one potential use of the spectrometer as a one-dimensional imager.
Market Regime Forecasting using Correlation Networks and Machine Learning Classifiers
Creators: name: Zhu, Fan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020
Subjects: subject: Machine learning
subject: Econometrics
subject: FOS: Economics and business
subject: Finance

description: Market regime classification has been practically influential to financial practitioners. Through the top-down approach to identify market regimes, we partition historical data on U.S. equity market returns into bear and bull markets (Hanna, 2018). Then we create a correlation network for each market state respectively. The topological features of those networks will be fed into the machine learning classifiers, which will provide a model whose machine learning algorithm generates the highest accuracy among all the candidate algorithms. We found that, with 1-months duration and 1-week lagged industry return data, the Fine Tree model has the highest forecasting accuracy of 91.7%. For data with longer horizon, the Kernel Naive Bayes model with 3-month duration and 12-month lagged data performs the best with an accuracy of 66.7%. The applications of the acquired model can not only benefit financial practitioners from acting in advance of the market, but also benefit macro-economists from preparing better for the extreme market events.
Ornithorhynchus anatinus (Platypus) genome sequencing and assembly
Creators: name: BGI
Publisher: name: CNGB
Year: 2019

description: The raw data and assembly of this submission are currently under a G10K-VGP publication embargo until removed from this description, following the G10K data use policy at the following URL: https://genome10k.soe.ucsc.edu/about/data_use_policy. The platypus is a monotreme mammal that has both reptile and mammalian traits, such as laying eggs and a duck bill like reptiles and birds, and a coat of fur like mammals. It is native to Australia. This reference assembly of has been produced as part of the G10K-VGP Project and a BGI project on mammal evolution. The male sample was collected for Guojie Zhang and sequenced at Pacific Biosciences, BGI for Illumina data, and the Rockefeller University Vertebrate Genome lab for Bioanano and 10X data. HiC data was generated from a different individual at Phase Genomics. Genome assembly was conducted by the G10K-VGP group, namely Arang Rhie and Sergey Koren of Adam Phillippy's lab at NIH. Manual curation of chromosomes and other genomic features was conducted by the gEVAL group led by Kerstin Howe at the Sanger Institute, Harris Lewin and Joanna Damas at UC Davis, the Phillippy Lab, and Guojie Zhang and Yang Zhou of BGI. The primary haplotype contains the longest contigs of the Pacbio FALCON unzip assembly, scaffolded with 10X linked reads, Bionano optical maps, and Phase Genomics HiC reads, with multiple tools to further separate out haplotypes. Funding was provided by Pacbio as part of a promotion, BGI to Guojie Zhang, HHMI and Rockefeller start-up funds to Erich Jarvis, and individual grants and awards to the persons listed above.
New Becomings in the Aftermath of Destruction: The Untold Stories of Syrian Women in Zaatari Refugee Camp
Creators: name: Jitan, Aisha
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: This project is based on an ethnographic study done in Zaatari Refugee Camp, a Syrian refugee camp based in Mafraq, Jordan. Through centering women's voices and engaging with first-hand accounts of the Syrian refugee crisis, this thesis explores what life for Syrian refugee women is like in the aftermath of the destruction of the Syrian Civil War. The research question driving this project is: How have health care services from the international aid community changed refugee women's economic mobility, religiosity, and gender dynamics? In answering this question, I use a feminist approach to consider the complex, nuanced, and multi-faceted lived experiences of Syrian women living in Zaatari refugee camp.
Guion del grupo focal dirigido a estudiantes del Grado en Maestro en Educación Primaria
Creators: name: Pineda-Martínez, María
Publisher: name: Zenodo
Year: 2024

description: Guion del grupo focal dirigido a estudiantes del Grado en Maestro en Educación Primaria

Anexo perteneciente a la Tesis Doctoral: Diseño Universal para el Aprendizaje (DUA) en la formación inicial de Maestros y Maestras de Educación Primaria
Quantum uncertainty and the spectra of symmetric operators
Creators: name: Martin, R. T. W.
name: Kempf, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In certain circumstances, the uncertainty, $ΔS [ϕ]$, of a quantum observable, $S$, can be bounded from below by a finite overall constant $ΔS>0$, \emph{i.e.}, $ΔS [ϕ] \geq ΔS$, for all physical states $ϕ$. For example, a finite lower bound to the resolution of distances has been used to model a natural ultraviolet cutoff at the Planck or string scale. In general, the minimum uncertainty of an observable can depend on the expectation value, $t=\langle ϕ, S ϕ\rangle$, through a function $ΔS_t$ of $t$, \emph{i.e.}, $ΔS [ϕ]\ge ΔS_t$, for all physical states $ϕ$ with $\langle ϕ, S ϕ\rangle=t$. An observable whose uncertainty is finitely bounded from below is necessarily described by an operator that is merely symmetric rather than self-adjoint on the physical domain. Nevertheless, on larger domains, the operator possesses a family of self-adjoint extensions. Here, we prove results on the relationship between the spacing of the eigenvalues of these self-adjoint extensions and the function $ΔS_t$. We also discuss potential applications in quantum and classical information theory.
Workflow models for heterogeneous distributed systems
Creators: name: Colonnelli, Iacopo
Publisher: name: Zenodo
Year: 2022
Subjects: subject: Scientific Workflows
subject: HPC
subject: Cloud Computing
subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: Literate Computing

description: The role of data in modern scientific workflows becomes more and more crucial. The unprecedented amount of data available in the digital era, combined with the recent advancements in Machine Learning and High-Performance Computing (HPC), let computers surpass human performances in a wide range of fields, such as Computer Vision, Natural Language Processing and Bioinformatics. However, a solid data management strategy becomes crucial for key aspects like performance optimisation, privacy preservation and security. Most modern programming paradigms for Big Data analysis adhere to the principle of data locality: moving computation closer to the data to remove transfer-related overheads and risks. Still, there are scenarios in which it is worth, or even unavoidable, to transfer data between different steps of a complex workflow. The contribution of this dissertation is twofold. First, it defines a novel methodology for distributed modular applications, allowing topology-aware scheduling and data management while separating business logic, data dependencies, parallel patterns and execution environments. In addition, it introduces computational notebooks as a high-level and user-friendly interface to this new kind of workflow, aiming to flatten the learning curve and improve the adoption of such methodology. Each of these contributions is accompanied by a full-fledged, Open Source implementation, which has been used for evaluation purposes and allows the interested reader to experience the related methodology first-hand. The validity of the proposed approaches has been demonstrated on a total of five real scientific applications in the domains of Deep Learning, Bioinformatics and Molecular Dynamics Simulation, executing them on large-scale mixed cloud-High-Performance Computing (HPC) infrastructures.
The Effects of Race-Related Rejection Sensitivity on Detection of Emotion in Faces
Creators: name: Scales, Sinclaire
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Research has indicated that both implicit and explicit forms of racial rejection can have adverse effects on psychological, physiological, and cognitive health. As a defense to various forms of discrimination, minority group members, such as Black/African Americans, may expect to be rejected because of their race in certain situations. This is termed race-based rejection sensitivity (RS-race). The goal of this study, was to determine whether the extent of a minority group members’ RS-race was associated with differential ascriptions of positive and negative emotions in Black and White faces. To address this, 121 Black/African American participants were recruited for an online study. Participants completed an RS-race questionnaire measure, and then completed a task wherein they classified various versions of Black and White faces that expressed two different percentages (intensities) of happiness or anger. Interestingly, higher RS-Race scores were associated with higher anger ratings for White faces, a trend not found for Black faces. However, there was no association between RS-race scores and the detection of happiness on Black or White faces. Participants detected happiness on White faces at higher intensities, significantly more than those at lower intensities. However, participants detected an even greater significant difference between Black faces at higher intensities and Black faces at lower intensities. The combination of null and significant results highlights the importance of future research in disentangling the link between RS-race and emotion detection.
Keywords: Race-Based Rejection Sensitivity (RS-Race), Emotion Detection
On the Relationship between Two Notions of Compatibility for Bi-Hamiltonian Systems
Creators: name: Santoprete, Manuele
Publisher: name: arXiv
Year: 2015
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Differential Geometry (math.DG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Bi-Hamiltonian structures are of great importance in the theory of integrable Hamiltonian systems. The notion of compatibility of symplectic structures is a key aspect of bi-Hamiltonian systems. Because of this, a few different notions of compatibility have been introduced. In this paper we show that, under some additional assumptions, compatibility in the sense of Magri implies a notion of compatibility due to Fassò and Ratiu, that we dub bi-affine compatibility. We present two proofs of this fact. The first one uses the uniqueness of the connection parallelizing all the Hamiltonian vector fields tangent to the leaves of a Lagrangian foliation. The second proof uses Darboux-Nijenhuis coordinates and symplectic connections.
Thermotropic Orientational Order of Discotic Liquid Crystals in Nanochannels: An Optical Polarimetry Study and a Landau-de Gennes Analysis
Creators: name: Kityk, Andriy V.
name: Busch, Mark
name: Rau, Daniel
name: Calus, Sylwia
name: Cerclier, Carole V.
name: Lefort, Ronan
name: Morineau, Denis
name: Bock, Harald
name: Grelet, Eric
name: Krause, Christina
name: Schoenhals, Andreas
name: Frick, Bernhard
name: Huber, Patrick
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Optical polarimetry measurements of the orientational order of a discotic liquid crystal based on a pyrene derivative and confined in parallel-aligned nanochannels of monolithic mesoporous alumina, silica, and silicon as a function of temperature, channel radius (3 - 22 nm) and surface chemistry reveal a competition of radial and axial columnar order. The evolution of the orientational order parameter of the confined systems is continuous, in contrast to the discontinuous transition in the bulk. For channel radii larger than 10 nm we suggest several, alternative defect structures, which are compatible both with the optical experiments on the collective molecular orientation presented here and with a translational, radial columnar order reported in previous diffraction studies. For smaller channel radii our observations can semi-quantitatively be described by a Landau-de Gennes model with a nematic shell of radially ordered columns (affected by elastic splay deformations) that coexists with an orientationally disordered, isotropic core. For these structures, the cylindrical phase boundaries are predicted to move from the channel walls to the channel centres upon cooling, and vice-versa upon heating, in accord with the pronounced cooling/heating hystereses observed and the scaling behavior of the transition temperatures with channel diameter. The absence of experimental hints of a paranematic state is consistent with a biquadratic coupling of the splay deformations to the order parameter.
description: 14 pages, 8 figures
末次冰期青藏高原和新西兰千年尺度的反相冰川波动数据.xls
Creators: name: Wang, Weicheng
name: wang, Jie
name: Qiu, Jinkun
name: Chen, Xiaojing
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 370502
subject: Geochronology

description: 表S1显示了来自其他研究人员的样本信息。表S2显示了P-CAAT分析的结果。表 S3 显示了详细的建模结果。表S4显示了用于计算质量平衡的高程处月平均气候数据的拟合度。
Indicators for the evaluation of science, technology and innovation activities: a systematized review (Complementary material to manuscript: ).
Creators: name: Ortiz-Núñez, Roelvis
name: Novo-Castro, Stephany
name: Casate-Fernández, Ricardo
Publisher: name: Zenodo
Year: 2023
Subjects: Indicators; Science; Technology; Innovation; Research evaluation.

description: The main purpose of this study was to develop a systematic review of the scientific literature about indicators for the evaluation of science, technology and innovation activities. For this, the Web of Science, Scopus and Google Scholar databases were used. Through the application of the SysteRe-HSS methodology, 96 publications were selected that formed the basis for a descriptive model of the science, technology and innovation indicators. The results of the research showed that there is a predominance of indicators related to the evaluation of innovation activities, human resources allocated to the activity of science, technology and innovation, financial resources and investments in research plus development, and indicators related to bibliometrics and scientometrics. However, challenges are faced related to measuring indicators of social innovation, linking insights from existing innovation measurement approaches with the essential features of social innovation, measuring the impact of social appropriation practices of science and technology, and the next generation metrics, responsible metrics and evaluation for open science, as well as alternative indicators for the evaluation of the social impact of research in web 2.0.
Human-AI Partnership In Underwriting: A Task-Centered Analysis of the Division of Work
Creators: name: Smith, Preston
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: The current conversation around automation and artificial intelligence (AI) has called for the task-centered analysis of work processes, to assess what future divisions of work between humans and AI will look like. In this study, I deconstructed--down to the task-level--the job of a credit analyst at a captive automotive finance company (the “Captive), in order to evaluate the automatability of their underwriting process. By breaking down the current partitioned division of labor between humans and the system, I was able to understand how the Captive handles the complexity of managing multiple stakeholders. From there, I highlighted features of the process that suggest a form of interdependent collaboration between humans and AI technologies will be the most effective form of partnership in contexts with these characteristics. I concluded with the understanding that future implementations of AI technologies without reimagining current partnerships will be counterproductive.
A thesis submitted to the school of graduate studies of Addis Ababa University in partial fulfillment of the requirement for the degree of Masters of Science in Economics (Resource and Environmental Economics)
Creators: name: BELAY KASAYE
Publisher: name: Zenodo
Year: 2015

description: This study examines the farmers" willingness to pay for improved soil conservation practices on

communal lands of Kuyu woreda in Ethiopia. The objective of this study is to investigate the

farmers" willingness to pay for improved soil conservation practices on communal lands of Kuyu

woreda. Both single and double-bounded dichotomous format of contingent valuation method is

used to elicit respondents" WTP for improved soil conservation practice in terms of labor

contribution. Data collected from 184 household heads were used for analysis. Both the Probit

and Bivariate Probit models were estimated. The result of the study indicated that most of the

respondents have perceived the problem of soil erosion and are willing to pay for conservation

practices. Household characteristics such as sex of household head, education level of the head

are significant determinants of farmers" WTP for soil conservation.
The Impact of Economic Sanctions on Labor Markets: A Micro-level Analysis of Russian Earnings and Job-Switch Behavior
Creators: name: Williams, Christian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: The true impact of economic sanctions on a targeted state has been widely debated, often through the analysis of macroeconomic data in historic case studies. This paper provides new insight into the effect of economic sanctions on earnings, job-switch behavior and employment through the adoption of micro-level data in Russia from 2010-2018 using the Russia Longitudinal Monitoring Survey (RLMS). Furthermore, this paper contributes a new methodology in estimating the severity of sanctions on a targeted state through correlating changes in stock prices to severity weights and generating a points system to track the ramifications of individual sanctions. This paper focuses on two primary points relating to Russian sanctions: 1) the sanctions imposed by the U.S. and E.U. on Russia in response to the Ukraine Crisis and 2) Russia’s retaliatory sanctions on agricultural imports as response to Western sanctions. I find that Western sanctions decrease Russian average monthly earnings while Russia’s retaliatory sanctions lead to an increase in earnings, domestic ownership and employment in the Russian agricultural sector. These findings display the microeconomic repercussions that are often overlooked in political and macroeconomic investigations into sanctions.
The ADM papers and part of their modern legacy: loop quantum gravity
Creators: name: Pullin, Jorge
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a summary for non-specialists of loop quantum gravity as part of the modern legacy of the series of papers by Arnowitt, Deser and Misner circa 1960.
description: 7 pages, prepared for Classical and Quantum Gravity for its "Milestones of General Relativity" focus issue to be published during the Centenary Year of GR
Auswertung der Online-Umfrage zur Literaturverwaltung an der TUHH – Zeitraum: 30. November 2021 bis 06. Januar 2022
Creators: name: Bieler, Detlev
name: Hagen, Florian
Publisher: name: TUHH Universitätsbibliothek
Year: 2022
Subjects: subject: Umfrage; Literaturverwaltung; Wissenschaftsorganisation
classificationCode: 020
subject: Bibliotheks- und Informationswissenschaft

description: Auswertung einer Umfrage zum Thema Literaturverwaltung an der Technischen Universität Hamburg (TUHH). Die Umfrage umfasst 26 Fragen und widmet sich den Themenblöcken "Ihre Erfahrungen mit Literaturverwaltung und dazugehöriger Software", "Ihre Erfahrungen mit Citavi Web" und "Persönliche und technische Voraussetzungen".
description: Evaluation of a survey on the topic of literature management at the Hamburg University of Technology (TUHH). The survey includes 26 questions and is dedicated to the topics "Your experiences with literature management and related software", "Your experiences with Citavi Web" and "Personal and technical requirements".
Electron spin coherence of shallow donors in natural and isotopically enriched germanium
Creators: name: Sigillito, A. J.
name: Jock, R. M.
name: Tyryshkin, A. M.
name: Beeman, J. W.
name: Haller, E. E.
name: Itoh, K. M.
name: Lyon, S. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Germanium is a widely used material for electronic and optoelectronic devices and recently it has become an important material for spintronics and quantum computing applications. Donor spins in silicon have been shown to support very long coherence times ($T_{2}$) when the host material is isotopically enriched to remove any magnetic nuclei. Germanium also has non-magnetic isotopes so it is expected to support long $T_{2}$s while offering some new properties. Compared to Si, Ge has a strong spin-orbit coupling, large electron wavefunction, high mobility, and highly anisotropic conduction band valleys which will all give rise to new physics. In this Letter, the first pulsed electron spin resonance (ESR) measurements of $T_{2}$ and the spin-lattice relaxation ($T_1$) times for $^{75}$As and $^{31}$P donors in natural and isotopically enriched germanium are presented. We compare samples with various levels of isotopic enrichment and find that spectral diffusion due to $^{73}$Ge nuclear spins limits the coherence in samples with significant amounts of $^{73}$Ge. For the most highly enriched samples, we find that $T_1$ limits $T_2$ to $T_2 = 2T_1$. We report an anisotropy in $T_1$ and the ensemble linewidths for magnetic fields oriented along different crystal axes but do not resolve any angular dependence to the spectral-diffusion-limited $T_2$ in samples with $^{73}$Ge.
Dynamic Polymer-Based Combinatorial Libraries for Selective Binding
Creators: name: Warren, Jacqueline
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Biological molecules such as proteins are able to bind to substrates with high selectivity and affinity in order to catalyze reaction or perform cell signaling, however the molecules are vulnerable to destructive processes such as denaturation, misfolding, and degradation by proteases. As an alternative, we have created a dynamic polymer-based combinatorial library that applies dynamic combinatorial chemistry (DCC) through reversible covalent bonds – we selected disulfide bonds – between the polymer scaffolds containing thiol-exchangeable monomers and an excess of free ligands containing a thiol moiety. The excess of ligands we refer to as dynamic building blocks (DBBs) composed of commercially available thiols and synthesized dipeptides. The dynamic polymer-based combinatorial library was modeled using design of experiments (DOE) to understand the effect of each of the parameters that diversify our polymer scaffolds. Two polymers were developed as “proof of concept” polymers to understand the impact of added hydrophobicity on size and demonstrate binding to free thiols in solution. It was concluded that added hydrophobicity does decrease the size of the polymer independent of the DBBs present in solution. Future DCC experimentation will be conducted under the same conditions as the DLS and bound DBBs will be quantified.