cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Host genotype interacts with aerial spore communities and influence the needle mycobiome of Norway spruce. Sequencing files and tags.
Creators: name: Redondo, Miguel Angel
Publisher: name: figshare
Year: 2022
Subjects: subject: 60202 Community Ecology (excl. Invasive Species Ecology)
subject: FOS: Biological sciences

description: This object contains the fastaq files from the Pacbio sequencing for the needles and spore traps and the tags for the demultiplexing of the reads. The tags for the ITS7 primer are the same for the library preparation of needles and spore trap samples. There is an excel file with the metadata of each of the samples, including library number and tag number.
Hölder continuity of the integrated density of states in the one-dimensional Anderson model
Creators: name: Hart, Eric
name: Virag, Balint
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We consider the one-dimensional random Schrodinger operator H = H_0 + sigma V, where the potential V has i.i.d. entries with bounded support. We prove that the IDS is Holder continuous with exponent 1-c sigma This improves upon the work of Bourgain showing that the Holder exponent tends to 1 as sigma tends to 0 in the more specific Anderson-Bernoulli setting.
Determining the mechanism underlying the effect of chloroquine in combination with an ERK inhibitor on pancreatic cancer cell proliferation
Creators: name: Zeitouni, Daniel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Background: Pancreatic cancer has a dismal 5-year survival rate of 9%. KRAS is
mutated in 98% of pancreatic ductal adenocarcinomas (PDACs), making the discovery
of a treatment for KRAS mutant cancers urgent. However, over 30 years of effort have
yet to yield a direct anti-KRAS therapeutic, thus a current focus of the field is targeting
downstream effectors of mutant KRAS.
Hypothesis: We hypothesize that the synergy seen between SCH772984 (SCH), an
ERK inhibitor, and chloroquine, an inhibitor of lysosomal acidification, is due to the
ability of chloroquine to block the cell from harnessing energy through autophagy.
Methods: HPAC, PANC-1, Pa14C and Pa01C cell lines were treated with a
combination of SCH and autophagy specific inhibitors Spautin-1, SBI-0206965 (SBI),
and MRT68921 (MRT). Cells were treated with the drugs alone and in combination with
SCH for 72 hours, and proliferation assays were used to quantify the effect on cell
growth. In a parallel line of investigation, ATG5 and ATG7 were genetically silenced
using shRNA in a panel of PDAC cell lines. Following western blot analyses to confirm
ATG5 or ATG7 knockdown, the sensitivity of these cells to SCH were compared to that
of parental cells using proliferation after 72 hours of treatment as a readout.
Results: Each autophagy inhibitor analyzed synergized with SCH in multiple PDAC cell
lines. For these studies, the autophagy inhibitors were held at constant concentrations,
while the SCH concentration was varied. Each of the drugs displayed the most synergy
with SCH at concentrations ranging from 0.156μM to 1.25μM. MRT consistently showed
the most synergy in our studies. In addition, growth curves of PDAC cells with ATG5 or
ATG7 knockdown demonstrated that genetic silencing of autophagy-related proteins
increase sensitivity to SCH treatment compared to wild type. PDAC cells became more
sensitive to SCH following each of these forms of autophagy inhibition in our studies.
Conclusion: Each of the autophagy inhibitors synergized with the ERK inhibitor in
multiple PDAC cell lines. Additionally, cells in which vital autophagy genes, ATG5 or
ATG7, were knocked down were more sensitive to SCH. These findings suggest that
the synergy between chloroquine and SCH is at least partially due to the inhibition of
autophagy.
Vowel Discrimination in German/English and French/English Bilingual Infants
Creators: name: Klassen, Jacquelyn
name: Soderstrom, Melanie
name: Bernier, Dana
name: White, Katherine
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: bilingual language acquisition
subject: infant speech perception
subject: vowel discrimination

description: This study is looking at whether German-English and French-English bilingual infants, as well as English, German, and French monolingual infants can discriminate vowel contrasts that may or may not exist in their language environments
Traumatic Initial Lumbar Punctures in Childhood Acute Lymphoblastic Leukemia: Predictive Factoors and Impact on Disease Outcome. A Clinical Quality Improvement Study
Creators: name: Covington, Caitlin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Background: Pediatric patients newly diagnosed with ALL undergo a LP to determine if
they have disease in their CNS. A LP can be traumatic, meaning leukemic cells are inadvertently
introduced into the CNS, resulting in worse outcomes for patients. Previous studies
have shown risk factors for a TLP include provider level, level of sedation, platelet count,
age, and race.
Purpose: The purpose of this study was to determine risk factors for a TLP in our patient
population in the current treatment era. The study secondarily aimed to determine if a TLP
was associated with relapse of ALL in the CNS.
Methods: This was a single-center, retrospective chart review. Patients were included if they
were pediatric patients (18 years or younger), newly diagnosed with ALL, and underwent a
diagnostic LP within 72 hours of diagnosis. Age, race, sex, risk stratification of ALL, treatment
protocol, serum WBC count, platelet count, number of platelet transfusions, CSF WBC
and RBC counts, presence of blasts in CSF, CNS status, BMI, level of sedation, location of procedure,
and level of performing practitioner were recorded.
Results: The study showed that location of LP (p=0.0380) in an OR and sedation under general
anesthesia (p=0.0099) were significantly associated with a decreased risk of TLP. The
study also showed that a TLP is associated with an increased risk of CNS relapse in pediatric
patients with ALL (p=0.0381).
Conclusion: LPs should be performed in an OR under general anesthesia. While our study
did not show that level of provider was significantly associated with TLPs, it is recommended
that the highest level of provider available perform the diagnostic LP.
Assessing the Social and Academic Supports in a STEM Living Learning Community
Creators: name: Rodgers, Grayson
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: This study focuses on a living learning community called the Chancellor’s Science Scholars
(CSS) Program. The program is committed to bringing in underrepresented students into the
science, technology, engineering, and mathematics (STEM) field. Scholars are offered
academic supports as well as social supports. Students provide assessments of their
experiences at the end of each year in the program. This study examines how community,
science identity, and science self-efficacy relate to students’ perceived benefit of and
satisfaction in the program. Results show that scholars’ science-self efficacy did not improve over time and that scholars’ sense of community decreased over time. Sense of community and science identity are significant predictors of community involvement. Excerpts from student end-of-year interviews are included in discussions for future research. These findings may serve to improve the CSS program, as well as STEM learning communities in development.
Chronic Pain History and its Relationship to Executive Function and Pain Perception
Creators: name: Taylor, Dillon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Chronic pain is a burdensome and potentially debilitating condition that affects approximately one-third of the United States population. A large body of research has indicated that individuals with chronic pain typically exhibit a number of deficits. Executive functioning levels are diminished, touch perception is amplified, and pain is perceived as more intense and unpleasant as compared to matched controls. While this literature is invaluable in characterizing the profile of chronic pain, little research has examined individuals with a history of chronic pain. The current study aims to fill this gap in the literature by examining executive functioning, touch perception, and conditioned pain modulation in individuals with a history of chronic pain. It was found that individuals with a history of chronic pain had better performance on an attentional control task (Stroop test) than control participants but no difference in a working memory task (Ospan). Those with a history of chronic pain exhibited a lower threshold for tactile (pressure) unpleasantness than control subjects, under baseline conditions, but not while simultaneously experiencing a painful thermal stimulus. These individuals also exhibited higher ratings of pressure sensation unpleasantness and intensity while simultaneously experiencing a painful thermal stimulus, but not during the neutral thermal stimulus. These results indicate that individuals with a history of chronic pain not only differ from individuals without a history of chronic pain but also from individuals (described in the literature) with current chronic pain. Future studies should aim to better understand the causal relationships among these variables and how they transform over an individual’s life course.
VAPOR Bioreactors for In Vitro Vascularization of FRESH 3D Bioprinted Collagen Tissues
Creators: name: Hudson, Andrew
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: In recent decades, the field of regenerative medicine has aimed to generate patient-specific tissues to treat various diseases, injuries, and improve drug development. Unfortunately, most engineering strategies are limited to thin 2D cell sheets that have resulted in minimal translational success. The failure to generate large (≥1 cm3) tissues stems from the inability to generate microvasculature for nutrient delivery which constrains tissue thickness to the limits of passive nutrient diffusion (~250 µm). This work aims to bridge the macro (>1 mm) and the micro (<1 mm) length scales of vascular engineering to create true multi-scale vasculature. Using freeform reversible embedding of suspended hydrogels (FRESH), I 3D bioprint millimeter-scale collagen vessels and integrate them with micron-scale cell-assembled capillaries. To achieve integration of the engineered vessels with cell-assembled capillaries, I developed a bioreactor system termed vasculature and perfusion organ-on-a-chip reactor (VAPOR) to perfuse FRESH printed collagenbased high-resolution internally perfusable scaffolds (CHIPS). This dissertation examines how the VAPOR perfusion of CHIPS containing a porous cell-ECM hydrogel drives angiogenesis to generate multi-scale vascularized tissues in vitro. The result of this work is a highly modular tissue engineering platform that can produce larger microvascularized human tissues for next-generation organ-specific research, repair, and drug development.
Orbital effect of magnetic field on the Majorana phase diagram
Creators: name: Nijholt, Bas
name: Akhmerov, Anton R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Studies of Majorana bound states in semiconducting nanowires frequently neglect the orbital effect of magnetic field. Systematically studying its role leads us to several conclusions for designing Majoranas in this system. Specifically, we show that for experimentally relevant parameter values orbital effect of magnetic field has a stronger impact on the dispersion relation than the Zeeman effect. While Majoranas do not require a presence of only one dispersion subband, we observe that the size of the Majoranas becomes unpractically large, and the band gap unpractically small when more than one subband is filled. Since the orbital effect of magnetic field breaks several symmetries of the Hamiltonian, it leads to the appearance of large regions in parameter space with no band gap whenever the magnetic field is not aligned with the wire axis. The reflection symmetry of the Hamiltonian with respect to the plane perpendicular to the wire axis guarantees that the wire stays gapped in the topologically nontrivial region as long as the field is aligned with the wire.
description: 5 pages, 6 figures, data available at http://dx.doi.org/10.4121/uuid:20f1c784-1143-4c61-a03d-7a3454914abb
Farm Population Estimates for 1977
Creators: name: Banks, Vera J.
name: Banks, Vera J.
Publisher: name: Unknown
Year: 1978
Subjects: subject: Community/Rural/Urban Development
subject: Labor and Human Capital
subject: Farm population
subject: Migration
subject: Regional analysis

description: The U.S. farm population was 7,806,000 in the 12-month period centered on April 1977. This was 450,000 (or 5.4 percent) lower than in 1976, and 1.9 million (or 19.6 percent) lower than in 1970. For the period 1970-77, the average net loss of farm population through migration and reclassification of residence from farm to nonfarm was 301,000 annually—an average rate of 3.3 percent. Among the Nation's four regions, the South continued to be the heaviest loser. The West exhibited stability in farm population in contrast to the rest of the country.
Low-Bandwidth Remote Sensing of Rare Events
Creators: name: George, Shilpa
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: subject: 80302 Computer System Architecture
subject: FOS: Computer and information sciences

description: Remote Sensing enables knowledge discovery from live data collected by unmanned probes. Planetary exploration, drone surveillance, and underwater sensing are three examples of domains in which remote sensing plays a central role. Near real-time knowledge acquisition of a rare target during such missions is challenging due to three extremes: low bandwidth, novelty of target, and class imbalance. We call the learning that happens in these extreme conditions as Live Learning. This is a new capability at the intersection of edge computing and machine learning. It aims to learn a model for a rare target from unlabeled data captured on distributed probes that are only reachable over a low-bandwidth network. The main contribution of this thesis is the design, implementation, and evaluation of Hawk, an interactive model-agnostic live learning system that enables the discovery of rare novel phenomena from a stream of extremely skewed unlabeled visual data capture on weakly-connected remote sensing probes. Hawk is designed to optimize the use of two critical resources: (a) the network bandwidth from the remote source to the human expert, and (b) the expert’s labeling bandwidth. Live Learning embodies a new semi-supervised learning algorithm to train models onthe-fly to discover instances of a target from very few initial labeled data. We show the effectiveness of Hawk by performing extensive validation on three very demanding publicly-available datasets from the domains mentioned above. Each of these datasets was released within the past few years, and has been used in recent ML research publications in its domain. Our experiments show that even at bandwidths as low as 12 kbps and a base rate of 0.1%, a team of 7 probes is able to use Hawk to discover up to 87% of the event instances that could have been discovered using a brute-force model. Such a model is created from advance knowledge, transmission and labeling of all mission data. Our results show 1.5X–2X improvement in recall when Live Learning in Hawk is combined with recent Few Shot Learning algorithms such as SnaTCHer. Our results also show how the use of Diversity Sampling can further improve recall in Hawk.
A complete and explicit solution to the three-dimensional problem of two fixed centres
Creators: name: Biscani, Francesco
name: Izzo, Dario
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present for the first time an explicit, complete and closed-form solution to the three-dimensional problem of two fixed centres, based on Weierstrass elliptic and related functions. With respect to previous treatments of the problem, our solution is exact, valid for all initial conditions and physical parameters of the system (including unbounded orbits and repulsive forces), and expressed via a unique set of formulae. Various properties of the three-dimensional problem of two fixed centres are investigated and analysed, with a particular emphasis on quasi-periodic and periodic orbits, regions of motion and equilibrium points.
description: Accepted for publication in MNRAS. 15 pages, 12 figures
Exploring the Efficiency of First-Order Proving Methods
Creators: name: Molinaro, Mark
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Many automated theorem proving applications rely on the DPLL algorithm for deciding the satisfiability of a set of propositional logic formulae. For first-order logic formulae, ground clauses within the Herbrand universe may be exhaustively enumerated below an incrementing size-bound and fed as input to DPLL. From even a cursory investigation of these enumerated clauses, it is evident that many of them have multiple repeated terms. Here, we explore a potential method for exploiting the size-bound by "cheating in" larger clauses with many repeating terms that may be relevant to the proof.
Host genotype interacts with aerial spore communities and influence the needle mycobiome of Norway spruce. Sequencing files and tags.
Creators: name: Redondo, Miguel Angel
Publisher: name: figshare
Year: 2021
Subjects: subject: 60202 Community Ecology (excl. Invasive Species Ecology)
subject: FOS: Biological sciences

description: This object contains the fastaq files from the Pacbio sequencing for the needles and spore traps and the tags for the demultiplexing of the reads. There is an excel file with the metadata of each of the samples, including library number and tag number.
Sea-ice deformation product derived from Sentinel-1 & RADARSAT Constellation Mission SAR imagery (2017-2022)
Creators: name: Bouchat, Amélie
name: Plante, Mathieu
name: Ringeisen, Damien
name: Lemieux, Jean-François
name: Tremblay, Bruno
name: Blain, Philippe
name: Howell, Stephen
name: Brady, Mike
name: Komarov, Alexander
Publisher: name: Zenodo
Year: 2023
Subjects: sea-ice deformation
SAR
RADARSAT
Sentinel-1
Arctic

description: What?
 Presentation of a new data set of Lagrangian sea-ice deformation derived from SAR imagery from Sentinel-1 and RADARSAT Constellation Mission from 2017 to 2023. The methods used to obtain the sea-ice strain rates are described, along with a spatio-temporal coverage analysis of the data set. Some preliminary results of deformation statistics obtained with the new data set at 24hrs and 72hrs are also presented. We finally show how the discrete pixel-based feature tracking can lead to an apparent checkerboard pattern of linear kinematic features (LKFs) in the deformation fields when low drift gradients lead to displacements below the pixel resolution. Note: Slide 9 is an animation of the available shear rate data for 2 consecutive weeks. The animation can be accessed by downloading the pdf and clicking on the image.
 Where?
 11th workshop of the International Ice Chart Working Group on Data Assimilation (IICWG-DA), in Oslo (Norway).
 When?
 March 22, 2023
A Waterfilling Algorithm for Multiple Access Point Connectivity with Constrained Backhaul Network
Creators: name: Ahmad, Syed Amaar
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: The 4G/5G paradigm offers User Equipment (UE) simultaneous connectivity to a plurality of wireless Access Points (APs). We consider a UE communicating with its destination through multiple uplinks operating on orthogonal wireless channels with unequal bandwidth. The APs are connected via a tree-like backhaul network with destination at the root and non-ideal link capacities. We develop a power allocation scheme that achieves a near-optimal rate without explicit knowledge of the backhaul network topology at transmitter side. The proposed algorithm waterfills a dynamic subset of uplinks using a low-overhead backhaul load feedback.
description: Accepted for IEEE Wireless Communication Letters June, 2015. Keywords: Optimization, Resource Allocation, HetNets, Feedback control, Small Cells
The Role of Hepatocyte Growth Factor in Obesity-induced Basal-like Breast Cancer
Creators: name: Essaid, Luma
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Obesity is a well-known modifiable risk factor for many diseases, including cancer. Recent
studies in mice and humans have demonstrated the significance of the microenvironment in
shaping cancer risk and progression. This study investigated the obesity-induced hepatocyte
growth factor (HGF)/cMET signaling pathway in promoting basal-like breast cancer (BBC), an
aggressive triple negative subtype of breast cancer with no targeted therapy. HGF is a secreted
protein released from stromal cells in an inactive form. Once activated, HGF binds to its receptor
cMET, a proto-oncogene, which activates pro-tumor signaling pathways. We have previously
demonstrated that obesity increases HGF/cMET in murine mammary glands and drives early
tumor onset in a genetically engineered mouse model (GEMM) of human BBC, C3(1)-Tag mice.
To test our hypothesis that weight loss would reverse the effects of obesity, mice were weaned at
3 weeks of age onto either a low fat (10% kcal from fat) or high fat (60% kcal from fat) diet. We
sought to investigate changes in the pro-tumor pathway after a diet switch at 10 weeks of age,
from 60% kcal from fat to 10%, by inducing weight loss prior to tumor onset. Importantly,
HGF/cMET expression in normal mammary glands, and cMET in tumors, was elevated with
obesity and was significantly reversed with weight loss. This study also quantified adipocyte area
in normal mammary and tumor tissue between the 10% kcal from fat and 60% kcal from fat diets
to study diet effects on adipocyte size. Interestingly, many of the HGF/cMET regulators, e.g.,
activators such as HGF-Activator, and inhibitors such as HGF-Activator Inhibitor were modified
in the weight-loss mice between Normal Associated Fibroblasts and Cancer Associated
Fibroblasts. Finally, we confirmed that C3(1)-Tag mammary tumor epithelial cells grown in
conditioned media from fibroblasts of differing diets, 10% and 60% kcal from fat, have
distinctive proliferation indices. In summary, these results indicate that low and high fat diets
have differential effects on murine phenotypes, including body weight, body composition, and
stromal microenvironment. Importantly, weight loss in adulthood is possible, which reversed the
obesity-mediated pro-tumorigenic pathway. Future research aims include implementing weight
loss as a preventative measure in human subjects and inhibiting the HGF/cMET pathway to
evaluate potential treatment for obesity-driven BBC.
Data Science Rosetta Stone: A Tutorial of and Translation between Data Science Programming Languages
Creators: name: Kearney, Elaine
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Data Science and Machine Learning enable researchers both in academic and industrial fields to analyze data and consequently make important decisions as well as predictions. Different programming languages are used in the pursuit of Data Science. However, it is difficult for researchers to switch between languages or learn a new language which is needed in working across interdisciplinary fields and when working with colleagues from diverse backgrounds. This paper discusses a resource created to demonstrate the commonalities between four different programming languages commonly used in Data Science: MATLAB, Python, R, and SAS. The work for this project came out of research completed both at the Australia New Zealand Banking Group (ANZ) headquarters in Melbourne, Australia, and at the University of North Carolina at Chapel Hill (UNC-CH). This research resulted in an online set of tutorials, which we refer to as the Data Science Rosetta Stone, which demonstrates common data science tasks in the same progression for each programming language. We demonstrate that all of these languages achieve similar results, though with different syntax and/or simplicity of code, and efficiency of execution.
Cosmology from quantum potential in a system of oscillating branes
Creators: name: Sepehri, Alireza
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Recently, some authors proposed a new mechanism which gets rid of the big-bang singularity and shows that the age of the universe is infinite. In this paper, we will confirm their results and predict that the universe may expand and contract many times in a system of oscillating branes. In this model, first, N fundamental strings transit to N M0-anti-M0-branes. Then, M0-branes join to each other and build an M8-anti-M8 system. This system is unstable, broken and two anti-M4-branes, a compactified M4-brane, an M3-brane in additional to one M0-brane are produced. The M3-brane wraps around the compactified M4-brane and both of them oscillate between two anti-M4-branes. Our universe is located on the M3-brane and interacts with other branes by exchanging the M0-brane and some scalars in transverse directions. By wrapping of M3-brane, universe contracts and generalized uncertainty principle or GUP emerges. By oscillating the compactified M4-M3-brane and approaching to one of anti-M4-branes, one end of M3-brane glues to the anti-M4-brane and other end remains sticking and wrapping around M4-brane. Then, by getting away of the M4-M3 system, M4 rolls, wrapped M3 opens and expansion epoch of universe begins. By closing the M4 to anti-M4, the square mass of some scalars become negative and they make a transition to a tachyonic phase. To remove these states, M4 rebounds, rolls, M3 wraps around it and universe contracts again. We show that that the scale factor of universe in this system only at $t\rightarrow -\infty$ shrinks to zero and thus, the age of our universe is infinity. Also, when tachyonic states disappear at the beginning of expansion branch, some extra energy is produced and leads to the inflation. This theory matches with quantum field theory prescriptions in four dimensions.
description: Accepted for publication in Modern Physics Letters A
Predicting the outcome of the growth of binary solids far from equilibrium
Creators: name: Mannige, Ranjan V.
name: Whitelam, Stephen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The growth of multicomponent structures in simulations and experiments often results in kinetically trapped, nonequilibrium objects. In such cases we have no general theoretical framework for predicting the outcome of the growth process. Here we use computer simulations to study the growth of two-component structures within a simple lattice model. We show that kinetic trapping happens for many choices of growth rate and inter-component interaction energies, and that qualitatively distinct kinds of kinetic trapping are found in different regions of parameter space. In a region in which the low-energy structure is an `antiferromagnet' or `checkerboard', we show that the grown nonequilibrium structure displays a component-type stoichiometry that is different to the equilibrium one but is insensitive to growth rate and solution conditions. This robust nonequilibrium stoichiometry can be predicted via a mapping to the jammed random tiling of dimers studied by Flory, a finding that suggests a way of making defined nonequilibrium structures in experiment.
Carbon balance as a mechanism for shade intolerance in American Sweetgum
Creators: name: Brown, Alexander
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Shade intolerant species may respond strongly to changes in light availability, particularly if other abiotic and biotic conditions change. Conversely, these same abiotic and biotic factors may promote weaker responses in shade tolerant species. Indeed, shade intolerant species generally have higher photosynthetic capacities than shade tolerant ones regardless of light availability (Valladares & Niinemets 2008), indicating that their inability to persist is due to other factors. Thus, shade intolerant species may be ideal for testing whether abiotic and biotic factors can influence a species’ ability to persist in the shade. In this study, I manipulated light, nitrogen, and enemy pressure to examine the three mechanisms through which seedlings of a shade intolerant tree species may maintain a positive carbon balance. I asked the following questions:
1)  How do light and nitrogen availability and enemy pressure affect total plant biomass?
2)  How do light and nitrogen availability affect allocation to above- and belowground biomass?
3)  How do light and nitrogen availability affect reallocation of belowground biomass, and does this reallocation affect tolerance of damage?
4) How do light and nitrogen availability affect resistance to damage?
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Subjects: ÐÐ¾Ð»Ð¾ÐºÐ¾Ð½Ð½Ð°Ñ Ð¾Ð¿ÑÐ¸ÐºÐ°
ÐÐ¿ÑÐ¸ÑÐµÑÐºÐ°Ñ ÑÐ²ÑÐ·Ñ

description: Ð Ð°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½Ð½Ð¾-Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ñ ÑÑÐ°ÐºÑÐ°Ð¼Ð¸, Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð½ÑÐ¼Ð¸ Ð¿Ð¾ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ñ Ð¿Ð°ÑÑÐ¸Ð²Ð½ÑÑ Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐµÑÐµÐ¹. ÐÐ¿Ð¸ÑÑÐ²Ð°ÑÑÑÑ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐ»ÐµÐ¼ÐµÐ½ÑÑ ÑÐ°ÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸: Ð¸ÑÑÐ¾ÑÐ½Ð¸Ðº Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¸Ð³Ð½Ð°Ð»Ð°, ÑÐ¾ÑÐ¾Ð¿ÑÐ¸ÐµÐ¼Ð½Ð¸Ðº, Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð²Ð¾Ð»Ð¾ÐºÐ½Ð¾ Ð¸ Ð¾Ð¿ÑÐ¾Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½Ð½ÑÐµ ÑÐ°Ð·Ð²ÐµÑÐ²Ð¸ÑÐµÐ»Ð¸, Ð¸Ñ ÐºÐ»ÑÑÐµÐ²ÑÐµ ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½ÑÐµ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ¸ Ð¸ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ. ÐÑÐ½Ð¾Ð²Ð½Ð¾Ðµ Ð²Ð½Ð¸Ð¼Ð°Ð½Ð¸Ðµ ÑÐ´ÐµÐ»ÐµÐ½Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ ÑÐ°Ð±Ð¾ÑÐ¾ÑÐ¿Ð¾ÑÐ¾Ð±Ð½Ð¾ÑÑÐ¸ Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½Ð½Ð¾-Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ñ Ð·Ð°Ð´Ð°Ð½Ð½ÑÐ¼Ð¸ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ°Ð¼Ð¸ Ð¸ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ð°Ð¼ ÑÐ°ÑÑÐµÑÐ°, Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²ÑÐ²Ð°ÑÑÐµÐ³Ð¾ Ð¿ÑÐ°Ð²Ð¸Ð»ÑÐ½ÑÑ ÑÐ°Ð±Ð¾ÑÑ ÑÐ¸ÑÑÐµÐ¼Ñ Ñ ÑÑÐµÑÐ¾Ð¼ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² Ð²ÑÐ±ÑÐ°Ð½Ð½ÑÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð². ÐÑÐ¿Ð¾Ð»ÑÐ·ÑÐµÑÑÑ Ð¿Ð¾Ð´ÑÐ¾Ð´ Ñ ÑÐ°Ð·Ð´ÐµÐ»ÐµÐ½Ð¸ÐµÐ¼ ÑÑÐ»Ð¾Ð²Ð¸Ð¹ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ ÑÐ°Ð±Ð¾ÑÑ Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½Ð½Ð¾-Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿ÐµÑÐµÐ´Ð°ÑÐ¸ Ð½Ð° Ð´Ð²Ðµ ÑÐ°ÑÑÐ¸, Ð½Ð° ÑÑÐ»Ð¾Ð²Ð¸Ñ ÑÐ¾Ð³Ð»Ð°ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð±Ð°Ð»Ð°Ð½ÑÐ° Ð´Ð»Ñ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸ Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¸Ð³Ð½Ð°Ð»Ð° Ð¸ Ð½Ð° ÑÑÐ»Ð¾Ð²Ð¸Ñ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ Ð±Ð°Ð»Ð°Ð½ÑÐ° Ð±ÑÑÑÑÐ¾Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ñ ÑÑÐµÑÐ¾Ð¼ ÐºÐ¾Ð½ÐµÑÐ½Ð¾Ð³Ð¾ Ð±ÑÑÑÑÐ¾Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ð²ÑÐµÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² ÑÐ¸ÑÑÐµÐ¼Ñ. Ð¢Ð°ÐºÐ¾Ð¹ Ð¿Ð¾Ð´ÑÐ¾Ð´ Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÐµÑ Ñ Ð¾Ð±ÑÐ¸Ñ Ð±Ð°Ð·Ð¾Ð²ÑÑ Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð¹ ÑÐ°Ð´Ð¸Ð¾ÑÐ¸Ð·Ð¸ÐºÐ¸ Ð¸ ÑÐ°Ð´Ð¸Ð¾ÑÐµÑÐ½Ð¸ÐºÐ¸ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑ Ð¾Ð³ÑÐ°Ð½Ð¸ÑÐµÐ½Ð¸Ñ Ð½Ð° Ð´Ð¾ÑÑÐ¸Ð¶Ð¸Ð¼ÑÐµ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½Ð½Ð¾-Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ²ÑÐ·Ð¸, ÑÐ¿Ð¾ÑÐ¾Ð±ÑÑÐ²ÑÐµÑ Ð¿Ð¾Ð½Ð¸Ð¼Ð°Ñ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ð¾Ð² ÑÑÐ½ÐºÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐ¼ÑÑÐ»Ð° Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð². ÐÐ»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð¾Ð±ÑÑÐ°ÑÑÐ¸ÑÑÑ Ð¿Ð¾ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÑÐ¼ 11.03.02, 11.04.02 Â«ÐÐ½ÑÐ¾ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐµ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¸ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ²ÑÐ·Ð¸Â»; 03.04.03 Â«Ð Ð°Ð´Ð¸Ð¾ÑÐ¸Ð·Ð¸ÐºÐ°Â»; 12.03.02, 12.04.02 Â«ÐÐ¿ÑÐ¾ÑÐµÑÐ½Ð¸ÐºÐ°Â»; 12.03.03, 12.04.03 Â«Ð¤Ð¾ÑÐ¾Ð½Ð¸ÐºÐ° Ð¸ Ð¾Ð¿ÑÐ¾Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸ÐºÐ°Â».
Profiling the Effects of the Tumor Associated Mononuclear Phagocyte System on Systemic Clearance, Tumor Delivery, and Efficacy of Nanoparticle Agents
Creators: name: White, Taylor F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The goal of this honors project was to compare the pharmacokinetics and efficacy of PLD to small molecule doxorubicin in two xenograft mouse models, one endometrial (i.e. HEC1A) and one ovarian (i.e. SKOV-3), with differing TAM densities as measured by H Score analysis. PLD concentrations were measured separately for drug still within the liposomal carrier (i.e. encapsulated) and drug released from the liposomal carrier (i.e. released). It is important to note that encapsulated drug is pharmacologically inactive and possesses the PK properties of the carrier molecule, while released drug is active and possesses the PK properties of the small molecule agent.
Advances in Statistical Gene Networks
Creators: name: Tian, Jinjin
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Gene networks hold immense importance in understanding the underlying mechanisms that govern cellular activities and organismal behavior. As the true gene interaction is not observable, people often resort to observable gene expression data to statistically infer the gene network. In this thesis, we address the immense challenges in the statistical gene network, including 1) benchmark tool for gene network estimation 2) nonlinear gene network estimation methods 3) the application of gene networks in Autism associated gene understanding. In Chapter 2, we address benchmarking imputation methods on gene coexpression estimation. We develop a new simulation tool that allows realistic simulation of a homogeneous cell group, heterogeneous cell groups, as well as complex cell groups relationships such as tree and trajectory structure, together with gene co-expression structure. We show the usefulness of our tool by accessing the effect of gene expression denoising methods on downstream gene co-expression estimation. In Chapter 3, we address the limitation of current gene co-expression estimation methods in capturing nonlinear relationships. We show that averaging cell-specific gene coexpression over a population gives a novel dependence measure that can detect any non-linear, non-monotone, and non-global relationship. We formally establish the consistency and robustness and demonstrate its advantage over a large family of dependence measures. In Chapter 4, we explore the application of various types of gene networks in a case study of identifying active genes associated with autism spectrum disorders (ASD). To enable a systematic investigation, we also develop a novel gene group interaction measure, which extends an existing idea addressing the challenges when the true gene groups are unknown to nonlinear setups. Using a unified network-assisted gene risk modeling, we found that some types of gene networks are evidently more useful than others for our task: they help identify an assortment of unique “active” and “reactive” gene communities that are biologically interesting.
(Why) Are the Left Perceived as Debt-Profligate?
Creators: name: Barnes, Lucy
name: Hicks, Timothy
Publisher: name: Open Science Framework
Year: 2022

description: Our goal with this study is to establish whether left-wing parties are perceived as more likely to increase levels of government borrowing, as compared to right-wing parties and/or centre parties. There is something of a folk wisdom that this perception does exist, as seen in assertions of its existence in papers that study issues relating to this issue (e.g. Cusack 1999; Eichengreen and Panizza 2016; Kraft 2017). While those papers have found no evidence that left-wing governments actually do lead to higher levels of government borrowing, to our knowledge, there are no papers that establish whether the perception of left debt-profligacy actually exists amongst the citizens/voters as a whole. In this project, we first seek to establish whether citizens/voters, on average, hold this view of left-wing parties. Following that, if appropriate, we seek to establish why such perceptions exist.
An On-line Variational Bayesian Model for Multi-Person Tracking from Cluttered Scenes
Creators: name: Ba, Sileye
name: Alameda-Pineda, Xavier
name: Xompero, Alessio
name: Horaud, Radu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Object tracking is an ubiquitous problem that appears in many applications such as remote sensing, audio processing, computer vision, human-machine interfaces, human-robot interaction, etc. Although thoroughly investigated in computer vision, tracking a time-varying number of persons remains a challenging open problem. In this paper, we propose an on-line variational Bayesian model for multi-person tracking from cluttered visual observations provided by person detectors. The contributions of this paper are the followings. First, we propose a variational Bayesian framework for tracking an unknown and varying number of persons. Second, our model results in a variational expectation-maximization (VEM) algorithm with closed-form expressions for the posterior distributions of the latent variables and for the estimation of the model parameters. Third, the proposed model exploits observations from multiple detectors, and it is therefore multimodal by nature. Finally, we propose to embed both object-birth and object-visibility processes in an effort to robustly handle person appearances and disappearances over time. Evaluated on classical multiple person tracking datasets, our method shows competitive results with respect to state-of-the-art multiple-object tracking models, such as the probability hypothesis density (PHD) filter among others.
description: 21 pages, 9 figures, 4 tables
Rural Education and Rural Labor Force in the Seventies
Creators: name: Fratoe, Frank A.
name: Fratoe, Frank A.
Publisher: name: Unknown
Year: 1978
Subjects: subject: Community/Rural/Urban Development
subject: Labor and Human Capital
subject: rural education
subject: rural schools
subject: rural labor force
subject: rural development

description: Rural public school education lags behind metro central and suburban public school education in virtually all areas. Rural schools, with less revenue and support staff, are educating students who are more likely to enroll in school later, complete fewer school years, score lower on national tests, and fail to attend college than metro students. Since a greater proportion of these students do not get the higher education necessary for white collar or professional jobs, they tend to enter the labor force in blue collar or other lower paying occupations.
Finding the Perfect Message: Millennials, Media and the Financial Service Industry
Creators: name: DeSalva, Carol
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: As the generation shaped by the Internet and the development of new technologies,
millennials communicate and engage differently with marketing messages than previous
generations. Financial service companies need to learn, adapt and deliver content to attract young
millennials to their services. This is crucial not just for these companies’ success, but also for the
wellbeing of the U.S. economy, which is currently in crisis as Social Security’s and Medicare’s
resources are becoming depleted.
Through focus groups, this study attempted to understand how college-attending
millennials ages 19 to 21 felt about financial services. In addition, these focus groups aimed to
determine what financial service marketing messages best engaged this demographic and which
of these messages had the most potential to persuade millennials to contact a financial advisor.
Results indicated participants preferred marketing content helped them trust the company and
relieved some uneasiness they felt towards financial planning. Results also indicated participants
were highly influenced third-party influencers, especially their parents. College-attending
millennials ages 19 to 21 looked to them for advice and guidance about financial services. Their
influence ultimately shaped their children’s financial attitudes.
Future research should consider which marketing messages best engage older
generations, such as Generation Xers and Baby Boomers. These generations can be used to target
college-attending millennials ages 19 to 21. Finding loyal clients in these older generations can
lead to more business from their millennial counterparts.
Infinitesimal change of stable basis
Creators: name: Gorsky, Eugene
name: Neguţ, Andrei
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: Combinatorics (math.CO)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: The purpose of this note is to study the Maulik-Okounkov $K-$theoretic stable basis for the Hilbert scheme of points on the plane, which depends on a "slope" $m \in \mathbb{R}$. When $m = \frac ab$ is rational, we study the change of stable matrix from slope $m-\varepsilon$ to $m+\varepsilon$ for small $\varepsilon>0$, and conjecture that it is related to the Leclerc-Thibon conjugation in the $q-$Fock space for $U_q\widehat{\mathfrak{gl}}_b$. This is part of a wide framework of connections involving derived categories of quantized Hilbert schemes, modules for rational Cherednik algebras and Hecke algebras at roots of unity.
description: 13 pages, 1 figure
Coherent control of group index and magneto-optical anisotropy in a multilevel atomic vapor
Creators: name: Lampis, Andreas
name: Culver, Robert
name: Megyeri, Balázs
name: Goldwin, Jon
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study electromagnetically induced transparency (EIT) in a heated potassium vapor cell, using a simple optical setup with a single free-running diode laser and an acousto-optic modulator. Despite the fact that the Doppler width is comparable to the ground state hyperfine splitting, transparency windows with deeply sub-natural line widths and large group indices are obtained. A longitudinal magnetic field is used to split the EIT feature and induce magnetooptical anisotropy. Using the beat note between co-propagating coupling and probe beams, we perform a heterodyne measurement of the circular dichroism (and therefore birefringence) of the EIT medium. The observed spectra reveal that lin-par-lin polarizations lead to greater anisotropy than lin-perp-lin. A simplified analytical model encompassing sixteen Zeeman states and eighteen \Lamda\ subsytems reproduces the experimental observations.
description: Published version; available with Open Access at https://www.osapublishing.org/oe/fulltext.cfm?uri=oe-24-14-15494
Aktivismus in der Archäologie als Chance
Creators: name: Wilts, Geesche
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Aktivismus
subject: Archäologie
subject: Empowerment
subject: 900 Geschichte und Geografie::900 Geschichte::901 Geschichtsphilosophie, Geschichtstheorie

description: Diesen Text schreibe ich aus meiner persönlichen Perspektive. Einerseits bin ich Archäologin, andererseits Aktivistin und verorte mich im linken politischen Spektrum. In einem selbstorganisierten Projekt habe ich 2015 auf Lampedusa Fluchtspuren mit archäologischen Methoden aufgespürt, dokumentiert und Objekte zur Anschauung mitgebracht, um im deutschsprachigen Teil Europas über die Grenzsituation aufzuklären, denn „the most violent element in society is ignorance“ (Goldman 1917: 2). Mit archäologischen Methoden möchte ich dieser Form der Gewalt entgegentreten, denn ich sehe den Nutzen archäologischer Methoden für Aktivist*innen. Dabei erfahre ich wiederholt Kritik aus dem Kollegium, welches befürchtet, die Wissenschaftlichkeit gehe durch solche Aktionen verloren. Im Folgenden beschäftigte ich mich daher mit beiden Aspekten. Hierbei werde ich beispielhaft immer wieder auf die Untersuchung der Fluchtspuren zurückgreifen und weitere Formen des Aktivismus aus dem linken Spektrum einbeziehen.
Analysis of slow transitions between nonequilibrium steady states
Creators: name: Mandal, Dibyendu
name: Jarzynski, Christopher
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Transitions between nonequilibrium steady states obey a generalized Clausius inequality, which becomes an equality in the quasistatic limit. For slow but finite transitions, we show that the behavior of the system is described by a response matrix whose elements are given by a far-from-equilibrium Green-Kubo formula, involving the decay of correlations evaluated in the nonequilibrium steady state. This result leads to a fluctuation-dissipation relation between the mean and variance of the nonadiabatic entropy production, $Δs_{\rm na}$. Furthermore, our results extend -- to nonequilibrium steady states -- the thermodynamic metric structure introduced by Sivak and Crooks for analyzing minimal-dissipation protocols for transitions between equilibrium states.
description: (5 + 3) pages
The Time and Space of Stimmung: Poetic Negotiations of Modernity in Hölderlin and Rilke
Creators: name: Hill, Andreas Freytag
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Ultimately, the significance of this undertaking lies in the way in which it recasts the
concept of Stimmung , positioning it on an axis of time and space and treats moods and
atmospheres not as the mere byproducts of texts, but as integral parts of their inner workings.
Comparing Hölderlin and Rilke allows one to focus on two distinct paradigms for the treatment
of Stimmung in poetry. Although it would obviously be going too far to suggest that each of
these paradigms is typical of the dominant theories of Stimmung around 1800 and 1900,
respectively, it is nevertheless the case that both poets are in many ways representative of the
eras in which they lived and wrote. Thus, one might say that each of these paradigms is, if not
typical, certainly one response to a changed (and changing) experience of reality.