cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Physiological role of PRRT2 and its involvement in the pathogenesis of paroxysmal disorders
Creators: name: ROMEI, ALESSANDRA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Mutations in the PRoline-Rich Transmembrane protein 2 gene (PRRT2) underlie a heterogeneous group of paroxysmal disorders encompassing infantile epilepsy, paroxysmal kinesigenic dyskinesia, a combination of these phenotypes and migraine. For the majority of the pathogenic PRRT2 variants, the mutant proteins are not expressed or not correctly targeted to the plasma membrane, resulting in a loss-of function mechanism for PRRT2-related diseases. PRRT2 is a neuron-specific, type II transmembrane protein of 340 amino acids with an important functional role in synapse formation and maintenance, as well as in the regulation of fast neurotransmitter release at both glutamatergic and GABAergic terminals. The PRRT2 knock-out (PRRT2-KO) mouse, in which PRRT2 has been constitutively inactivated, displays alterations in brain structure and a sharp paroxysmal phenotype, reminiscent of the most common clinical manifestations of the human PRRT2-linked diseases. To gain further insights on the pathogenic role of PRRT2 deficiency, I used Multi-Electrode Arrays (MEAs) to characterize neuronal activity generated by primary hippocampal cultures obtained from the PRRT2-KO mouse embryos and to assess the epileptic propensity of cortico-hippocampal slices obtained from the same animal model. This experimental approach revealed a state of heightened spontaneous activity, hyper-synchronization in population bursts of action potentials (APs) and enhanced responsiveness to external stimuli in mutant networks. A complex interplay between (i) a synaptic phenotype, with weakened spontaneous transmission and increased short-term facilitation, and (ii) a marked increase in intrinsic excitability of excitatory neurons as assessed by single-cell electrophysiology, upholds this network phenotype. Furthermore, our group has generated cortical neurons from induced pluripotent stem cells (iPSCs) derived from heterozygous and homozygous siblings carrying the most common C.649dupC mutation. Patch-clamp recordings in neurons from homozygous patients showed an increased Na+ current that was fully rescued by expression of exogenous wild-type PRRT2. A strikingly similar electrophysiological phenotype was observed in excitatory primary cortical neurons from the PRRT2-KO mouse, which was accompanied by an increased length of the axon initial segment (AIS). At the network level, mutant cortical neurons grown on MEAs also displayed a state of spontaneous and evoked hyper-excitability and elevated propensity to synchronize their activity in network bursting events.
Effect of tyrosine kinase inhibitors on NK cell and ILC3 dvelopment and function
Creators: name: DAMELE, LAURA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Tyrosin kinase inhibitors (TKI) sharply improved the prognosis of Chronic Myeloid
Leukemia (CML) and of Philadelphia+ Acute Lymphoblastic Leukemia (Ph+ALL) patients.
However, TKI are not curative because of the development of resistance and
lack of complete molecular remission in the majority of patients. Clinical evidences
would support the notion that patient?s immune system may play a key role in
preventing relapses. In particular, increased proportions of terminally differentiated
CD56+CD16+CD57+ NK cells have been reported to be associated with successful
Imatinib therapy discontinuation or with a deep molecular response in Dasatinib-treated
patients. In view of the potential role of NK cells in immune-response against
CML, it is important to study whether any TKI have an effect on the NK cell
development and identify possible molecular mechanism(s) by which continuous
exposure to in vitro TKI may influence NK cell development and repertoire. To
this end, CD34+ hematopoietic stem cells (HSC) were cultured in the absence or
in the presence of Imatinib, Nilotinib, or Dasatinib. We show that all compounds
exert an inhibitory effect on CD56+ cell recovery. In addition, Dasatinib sharply
skewed the repertoire of CD56+ cell population, leading to an impaired recovery
of CD56+CD117?CD16+CD94/NKG2A+EOMES+ mature cytotoxic NK cells, while
the recovery of CD56+CD117+CD94/NKG2A?RORgt+ IL-22-producing ILC3 was not
affected. This effect appears to involve the Dasatinib?mediated inhibition of Src kinases
and, indirectly, of STAT5-signaling activation in CD34+ cells during first days of culture.
Our studies, reveal a possible mechanism by which Dasatinib may interfere with the
proliferation and maturation of fully competent NK cells, i.e., by targeting signaling
pathways required for differentiation and survival of NK cells but not of ILC3.
Elaborazione di immagini digitali: applicazioni innovative ai materiali dell'arte come guida per interventi di conservazione e restauro
Creators: name: MANFREDI, EMANUELA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Confronto ed individuazione di diversi metodi per la caratterizzazione della macchina fotografica al fine di poterla paragonale ed affiancarla a studi colorimetrici effettivi.
Rapidity distribution dependence of the transition energy in heavy-ion collisions
Creators: name: Kumar, Sanjeev
name: Kumar, Suneel
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: For the present analysis, simulations are carried out for thousand of events for the reaction of 79Au197 + 79Au197 at semi-central geometry using a hard equation of state. The whole of the analysis is performed for light charged particles (LCP's). The transition from in-plane to out-of-plane is observed only when the mid-rapidity region is included in the rapidity bin otherwise no transition is observed. The transition energy is found to be strongly dependent on the size of the rapidity bin. The transition energy is parameterized with a straight line interpolation.
description: 3 Pages, 2 Figures
Seismic performance evaluation of circular reinforced concrete bridge piers retrofitted with fibre reinforced polymer
Creators: name: Parghi, Anantray M.
Publisher: name: University of British Columbia
Year: 2016

description: A large number of researchers around the globe are currently conducting investigations on the use of fibre-reinforced polymer (FRP) for strengthening of reinforced concrete (RC) bridge piers. It has been observed that such strengthening technique can be a cost-effective method for restoring and increasing the strength and ductility of piers damaged during catastrophic events, like earthquakes. Material properties, amount of longitudinal and transverse steel, external confinement, axial load and shear span-depth ratio affect the lateral load capacity, ductility and failure mode of retrofitted bridge piers under seismic load. These parameters are considerably different in the pre-1970 code designed RC bridge piers compared to the current seismically designed bridges. This research investigates the effect of different factors and their interactions on the limit states of FRP-confined seismically deficient RC circular bridge piers using factorial design method. Nonlinear static pushover analyses of the non-seismically designed FRP retrofitted circular bridge piers are conducted in order to determine the sequence of different limit states such as yielding of reinforcement, and concrete crushing along with ductility capacity of the piers. In addition, nonlinear reverse cyclic, and dynamic time-history analyses are carried out in order to determine the lateral load carrying capacity, flexural ductility, and hysteretic behavior of such retrofitted piers. Fragility curves are developed for the FRP retrofitted RC bridge piers considering different limit states of displacement ductility as the demand parameter. The incremental dynamic analysis is conducted by considering 20 ground motion records to investigate the nonlinear dynamic behavior of the retrofitted piers. The fragility curves are described using lognormal distribution functions with two parameters developed as a function of peak ground acceleration. The impact of various parameters is evaluated on the bridge pier fragility curve based on the theory of probability. This study shows that the shear span-depth ratio, the yield strength of reinforcement, longitudinal reinforcement ratio, axial load and FRP confinement significantly affect the lateral load capacity, ductility and the failure mode of the retrofitted bridge piers under seismic load.
Irreversibility and Entropy Production in Transport Phenomena I
Creators: name: Suzuki, Masuo
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: *First-principles derivation of the entropy production in erectric static conduction. *The second-order (symmetric) density matrix contributes to the entropy production. *New schemes of steady states formulated using a relaxation-type von Neumann equation. *Stationary temperature is introduced to characterize steady states. *The mechanism of the entropy production in steady states is also clarified.
description: Physica A (2011) in press
The Friedrichs Model and its use in resonance phenomena
Creators: name: Gadella, M.
name: Pronko, G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present here a relation of different types of Friedrichs models and their use in the description and comprehension of resonance phenomena. We first discuss the basic Friedrichs model and obtain its resonance in the case that this is simple or doubly degenerated. Next, we discuss the model with $N$ levels and show how the probability amplitude has an oscillatory behavior. Two generalizations of the Friedrichs model are suitable to introduce resonance behavior in quantum field theory. We also discuss a discrete version of the Friedrichs model and also a resonant interaction between two systems both with continuous spectrum. In an Appendix, we review the mathematics of rigged Hilbert spaces.
description: 105 pages
MPEC 2023-H227 : COMET P/2010 OE101 = P/2021 LJ31 (WISE)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: COMET P/2010 OE101 = P/2021 LJ31 (WISE)

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Influence of disorder on conductance in bilayer graphene under perpendicular electric field
Creators: name: Miyazaki, Hisao
name: Tsukagoshi, Kazuhito
name: Kanda, Akinobu
name: Otani, Minoru
name: Okada, Susumu
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Electron transport in bilayer graphene placed under a perpendicular electric field is revealed experimentally. Steep increase of the resistance is observed under high electric field; however, the resistance does not diverge even at low temperatures. The observed temperature dependence of the conductance consists of two contributions: the thermally activated (TA) conduction and the variable range hopping (VRH) conduction. We find that for the measured electric field range (0 - 1.3 V/nm) the mobility gap extracted from the TA behavior agrees well with the theoretical prediction for the band gap opening in bilayer graphene, although the VRH conduction deteriorates the insulating state more seriously in bilayer graphene with smaller mobility. These results show that the improvement of the mobility is crucial for the successful operation of the bilayer graphene field effect transistor.
Bilayer superfluidity of fermionic polar molecules: many body effects
Creators: name: Baranov, M. A.
name: Micheli, A.
name: Ronen, S.
name: Zoller, P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the BCS superfluid transition in a single-component fermionic gas of dipolar particles loaded in a tight bilayer trap, with the electric dipole moments polarized perpendicular to the layers. Based on the detailed analysis of the interlayer scattering, we calculate the critical temperature of the interlayer superfluid pairing transition when the layer separation is both smaller (dilute regime) and of the order or larger (dense regime) than the mean interparticle separation in each layer. Our calculations go beyond the standard BCS approach and include the many-body contributions resulting in the mass renormalization, as well as additional contributions to the pairing interaction. We find that the many-body effects have a pronounced effect on the critical temperature, and can either decrease (in the very dilute limit) or increase (in the dense and moderately dilute limits) the transition temperature as compared to the BCS approach.
description: 23 pages, 10 figures, final approval from S. Ronen was not received due to his no-response
Functional analysis of FtsZ1-2 in the cytoplasm of Physcomitrella patens (Hedw.) B.S.G
Creators: name: Neumann, Marianne
Publisher: name: Karlsruhe
Year: 2008

description: Of the five isoforms of FtsZ in the moss P. patens, FtsZ1-2 is the only one with a transit peptide that targets it to the chloroplast as well as the cytoplasm. To show a function of this protein, various exogenous factors have been tested on knock- out-, over-expression-, and wildtype cell-lines. It could be shown, that the formation of GFP-fluorescent structures is depending on light intensity and Cytokinine concentration. Influences of FtsZ1-2 on branching, cell- length, differentiation and light perception where also tested.
EFFECTS OF TWO HIGH-INTENSITY INTERVAL TRAINING CONCEPTS ON PHYSIOLOGICAL AND PERFORMANCE PARAMETERS OF RECREATIONAL RUNNERS
Creators: name: FERRANDO, MARA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: This study investigated the effects induced by 8 weeks of two high-intensity interval training (HIIT) protocols, 10-20-30 and 30-30 concepts, characterized by significantly different train-ing volume and intensity, on physiological parameters, running performance, body composition and psychophysiological stress of recreational divided into two groups: the 10-20-30 group performed two 10-20-30 sessions/wk and one con-tinuous training (CT)/wk, whilst the 30-30 group performed two 30-30 sessions/wk and one CT session/wk. VO2max, 1 km time, maximal aerobic speed (MAS), and body composition were evaluated before and after intervention. Internal load was measured through rating of perceived exertion (RPE). Both groups significantly improved running performance (1 km time: p = 0.04; MAS: p = 0.000001), aerobic fitness (VO2max: p=0.000002) and body composition (lean mass (kg) p=0.0001; fat mass ( %) p = 0.00005). RPE resulted significantly lower in the 10-20-30 group than in 30-30 group (10-20-30: 13.36 � 0.28; 30-30:15.55 � 0.21; p = 0.0002). Thus, the 10-20-30 group improved physiological parameters, performance and body composition, similar to 30-30 with significantly lower RPE values. These results suggest that in recreational runners the 10-20-30 training is effective in improving aerobic fitness and performance, with a lower subjective perception of effort, thus enhancing individual compliance and adherence to the pre-scribed training program
Discovery of the X-ray selected galaxy cluster XMMU J0338.8+0021 at z = 1.49 - Indications for a young system with a forming brightest galaxy
Creators: name: Nastasi, Alessandro
name: Fassbender, Rene
name: Böhringer, Hans
name: Šuhada, Robert
name: Rosati, Piero
name: Pierini, Daniele
name: Verdugo, Miguel
name: Santos, Joana S.
name: Schwope, Axel D.
name: de Hoon, Arjen
name: Kohnert, Jan
name: Lamer, Georg
name: Mühlegger, Martin
name: Quintana, Hernan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report on the discovery of a galaxy cluster at z = 1.490 originally selected as an extended X-ray source in the XMM-Newton Distant Cluster Project. Further observations carried out with the VLT-FORS2 spectrograph allowed the spectroscopic confirmation of seven secure cluster members, providing a median system redshift of z = 1.490 +/- 0.009. The color magnitude diagram of XMMU J0338.8+0021 reveals the presence of a well populated red sequence with z-H ~ 3, albeit with an apparent significant scatter in color. Since we do not detect indications for strong star formation activity in any of the objects, the color spread could indicate different stellar ages of the member galaxies. In addition, we found the brightest cluster galaxy in a very active dynamical state, with an interacting, merging companion located at a physical projected distance of d ~ 20kpc. From the X-ray luminosity we estimate a cluster mass of M200 ~ 1.2 x 10^(14) Msun. The data seem to suggest a scenario in which XMMU J0338.8+0021 is a young system, possibly caught in a moment of active ongoing mass assembly.
description: 6 pages, 4 figures, 2 Tables
Additional file 1 of Variations of chlorophyll-a and particulate organic carbon in the Yellow-Bohai Sea: in response to the Typhoon Lekima event
Creators: name: Wang, Xiaowen
name: Wang, Xiujun
name: You, Zai-Jin
Publisher: name: figshare
Year: 2021
Subjects: subject: Oceanography
subject: FOS: Earth and related environmental sciences

description: Additional file 1: Fig. S1. Current velocity in 1–8th August (a, d), 11–13th August (b, e), and 14–21st August (c, f) for non-typhoon years (top panel) and 2019 (lower panel) in the Yellow-Bohai Sea. Fig. S2. Ekman Pump velocity in 1–8th August (a, d), 11–13th August (b, e) and 14–21st August (c, f) for non-typhoon years (top panel) and 2019 (lower panel) in the Yellow-Bohai Sea. Fig. S3. Sea Surface Temperature (SST) in 1–8th August (a, d), 11–13th August (b, e) and 14–21st August (c, f) for non-typhoon years (top panel) and 2019 (lower panel) in the Yellow-Bohai Sea. Fig. S4. Sea surface salinity during 1–8th August (a), 11–13th August (b) and 14–21st August (c) for 2019 as well as the difference (d) between the first and last period in the Yellow-Bohai Sea. Fig. S5. Difference of euphotic depth between 1–8th and 14–21st August in 2019 in the Yellow-Bohai Sea.
Museomics Illumina Library Preparation Method
Creators: name: Twort, Victoria
Publisher: name: figshare
Year: 2021
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences
subject: Molecular Biology

description: Library preparation method used for construction of Illumina WGS libraries from museum specimens.
Method used in Twort et al. "Museomics of a rare taxon: placing Whalleyanidae in the Lepidoptera Tree of Life"
Ein Ansatz zur Modellierung von Vegetation für Gebäude- und Umweltaerodynamische Windkanaluntersuchungen
Creators: name: Gromke, Christof
name: Ruck, Bodo
Publisher: name: Karlsruhe
Year: 2008

description: Modellbäume für gebäude- und umweltaerodynamische Windkanaluntersuchungen wurden nach einem speziellen Modellierungsansatz, der eine Realisierung verschiedener Kronenpo-rositäten erlaubt, hergestellt. Ziel war es, die Auswirkungen der Porosität auf den Strö-mungswiderstand und das Geschwindigkeitsfeld der Um- bzw. Nachlaufströmung zu unter-suchen und die aerodynamischen Eigenschaften realer Bäume nachzubilden.
Die Ergebnisse der Widerstands- und Geschwindigkeitsmessungen zeigen keine ausgepräg-ten Abhängigkeiten vom Kronenporositätsgrad. Die Widerstandskoeffizienten der Modell-bäume sind denen von Naturbäumen bei Windgeschwindigkeiten unter 10 m/s vergleichbar. Sämtliche Strömungsgrößen der Nachlaufgebiete besitzen die typischen Charakteristiken durchströmter poröser Körper mit im Vergleich zu nicht-porösen Strukturen weiter stromab ausgedehnten Nachlaufgebieten.
Die Ergebnisse legen den Widerstandsbeiwert als eine grundlegend bestimmende Ähnlich-keitszahl für die kleinskalige strömungsmechanische Modellierung nahe. Der Modellierungs-ansatz zeigt sich geeignet, poröse Vegetationsstrukturen wie Bäume oder Sträucher für den Einsatz in gebäude- und umweltaerodynamischen Windkanaluntersuchungen nachzubilden, sofern keine Starkwindsituationen vorliegen. Beispiele hierfür sind Untersuchungen zum Windkomfort, zur Schadstoffausbreitung und Deposition luftgetragener Partikel, zur Ausbrei-tung von Waldbränden sowie zu Austauschprozessen skalarer Größen wie Feuchte, Wärme und biogenen Emissionen zwischen Waldbeständen und der Atmosphäre.
THE IMPORTANCE OF LEARNING OF THE SECOND LANGUAGE AND ITS DIFFICULTIES
Creators: name: Qulaxmedova, Gulnora
Publisher: name: Zenodo
Year: 2023

description: There have been so many offers in English language teaching in the education technology market in recent years , the question is, "What method do you teach?" The question becomes more relevant, as evidenced by the growing level of consumers of intellectual products. In our fast-paced world, where the education market offers all kinds of language courses , those who see time as gold and want to develop their work, this article helps them. So how effective are these teaching methods ? Do they give the expected n result?
Quantum Scalar-metric Cosmology with Chaplygin gas
Creators: name: Majumder, Barun
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A spatially flat Friedmann-Robertson-Walker(FRW) cosmological model with generalized Chaplygin gas is studied in the context of scalar-metric formulation of cosmology. Schutz's mechanism for the perfect fluid is applied with generalized Chaplygin gas and the classical and quantum dynamics for this model is studied. It is found that the only surviving matter degree of freedom played the role of cosmic time. For the quantum mechanical description it is possible to find the wave packet which resulted from the linear superposition of the wave functions of the Schrödinger-Wheeler-DeWitt(SWD) equation, which is a consequence of the above formalism. The wave packets show two distinct dominant peaks and propagate in the direction of increasing scale factor. It may happen that our present universe originated from one of those peaks. The many-world and ontological interpretation of quantum mechanics is applied to investigate about the behaviour of the scale factor and the scalar field(considered for this model). In both the cases the scale factor avoids singularity and a bouncing non-singular universe is found.
description: 13 pages, 6 figures
Design, fabrication, and characterization of a magnetic porous pdms as an on-demand drug delivery device
Creators: name: Shademani, Ali
Publisher: name: University of British Columbia
Year: 2016

description: We introduce a novel, on-demand drug delivery device based on a biocompatible magnetic sponge. The sponge is made of a porous polydimethylsiloxane (PDMS) mixed with carbonyl iron (CI) particles. The sponge is deformed under a magnetic field and consequently leads to releasing its contents. As a proof of concept study, three different CI/PDMS wt% ratios of 50%, 100%, and 150% were selected where, the 100% showed the most deformation under various magnetic fields. Although this sponge can solely be used as a potential drug delivery agent, a separate reservoir has been fabricated to protect the sponge and control the release rate. The final device has a diameter of 6 mm with a thickness of 2 mm. Controlled release of methylene blue (MB) and docetaxel (DTX) have been investigated to demonstrate the consistency and flexibility in adjusting the release rate from the device to suit different treatment requirements. Ex vivo tissue implantation has also been accomplished. This device is able to be implanted and deliver therapeutic agents at prescribed dosages.
Memory for sounds: novel technological solutions for the evaluation of mnestic skills
Creators: name: SETTI, WALTER
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Working memory (WM) plays a crucial role in helping individuals to perform everyday
activities. The neural structures underlying this system continue to develop during infancy
and reach maturity only late in development. Despite useful insights into visual memory
mechanisms, audio-spatial memory has not been thoroughly investigated, especially in children and congenitally blind individuals.
The main scientific objective of this thesis was to increase knowledge of spatial WM and
imagery abilities in the auditory modality. We focused on how these skills change during
typical development and on the consequences of early visual deprivation. Our first hypothesis
was that the changes in WM functionality and spatial skills occurring in the early years of
life, influence the ability to remember and associate spatialized sounds or to explore and
learn acoustic spatial layouts. Since vision plays a crucial role in spatial cognition (ThinusBlanc and Gaunet, 1997), we expected blind individuals to encounter specific difficulties
when asked to process and manipulate spatial information retained in memory, as already
observed in the haptic modality (Cattaneo et al., 2008; Vecchi, 1998). Although some studies
demonstrated the superior performance of the blind in various verbal-memory tasks (Amedi
et al., 2003; Po?�r, 1982; R�der et al., 2001), very little is known on how they remember and
manipulate acoustic spatial information.
The investigation of auditory cognition often requires specially adapted hardware and software solutions rarely available on the market. For example, in the case of studying cognitive
functions that involve auditory spatial information, multiple acoustic spatial locations are
required, such as numerous speakers or dedicated virtual acoustics. Thus, to the aim of this
thesis, we took advantage of novel technological solutions developed explicitly for delivering
non-visual spatialized stimuli. We worked on the software development of a vertical array
of speakers (ARENA2D), an audio-tactile tablet (Audiobrush), and we designed a system
based on an acoustic virtual reality (VR) simulation. These novel solutions were used to
adapt validated clinical procedures (Corsi-Block test) and games (the card game Memory) to
the auditory domain, to be also performed by visually impaired individuals. Thanks to the
technologies developed in these years, we could investigate these topics and observed that
audio-spatial memory abilities are strongly affected by the developmental stage and the lack
of visual experience.
Additional file 1 of The impact of cross-docked poses on performance of machine learning classifier for protein–ligand binding pose prediction
Creators: name: Shen, Chao
name: Hu, Xueping
name: Gao, Junbo
name: Zhang, Xujun
name: Zhong, Haiyang
name: Wang, Zhe
name: Xu, Lei
name: Kang, Yu
name: Cao, Dongsheng
name: Hou, Tingjun
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Additional file 1: Additional Tables and Figures.
Disorder and Electronic Transport in Graphene
Creators: name: Mucciolo, Eduardo R.
name: Lewenkopf, Caio H.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In this review, we provide an account of the recent progress in understanding electronic transport in disordered graphene systems. Starting from a theoretical description that emphasizes the role played by band structure properties and lattice symmetries, we describe the nature of disorder in these systems and its relation to transport properties. While the focus is primarily on theoretical and conceptual aspects, connections to experiments are also included. Issues such as short versus long-range disorder, localization (strong and weak), the carrier density dependence of the conductivity, and conductance fluctuations are considered and some open problems are pointed out.
description: 18 pages, 5 figures, Topical Review
D5.4 Intermediate Business Case implementation report
Creators: name: Coppens, Tuna
name: Ilias, Panagiotis
name: Callens, Bert
Publisher: name: Zenodo
Year: 2022

description: D5.4 “Intermediate BC Implementation Report” aims to identify the current status of BC implementation, ongoing developments and achievements of Envision data products and services. This report is crucial and one of the key milestones of the project as a way of reflecting on the work done in the previous years and assessing whether any changes and/or actions are needed based on the lessons learned from BC activities and progress to support the improvement of the ENVISION’s data products and services and commercialisation and dissemination activities.
Origin of the hysteresis in bilayer 2D systems in the quantum Hall regime
Creators: name: Ho, L. H.
name: Taskinen, L. J.
name: Micolich, A. P.
name: Hamilton, A. R.
name: Atkinson, P.
name: Ritchie, D. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The hysteresis observed in the magnetoresistance of bilayer 2D systems in the quantum Hall regime is generally attributed to the long time constant for charge transfer between the 2D systems due to the very low conductivity of the quantum Hall bulk states. We report electrometry measurements of a bilayer 2D system that demonstrate that the hysteresis is instead due to non-equilibrium induced current. This finding is consistent with magnetometry and electrometry measurements of single 2D systems, and has important ramifications for understanding hysteresis in bilayer 2D systems.
description: 4 pages, 3 figs. Accepted for publication in PRB
New constraint on cosmological variation of the proton-to-electron mass ratio from Q0528-250
Creators: name: King, Julian A.
name: Murphy, Michael T.
name: Ubachs, Wim
name: Webb, John K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Molecular hydrogen transitions in quasar spectra can be used to constrain variation in the proton-to-electron mass ratio, $μ\equiv m_p/m_e$, at high redshifts ($z\gtrsim 2$). We present here an analysis of a new spectrum of the quasar Q0528$-$250, obtained on VLT/UVES (the Ultraviolet and Visual Echelle Spectrograph, on the Very Large Telescope), and analyse the well-known H$_2$ absorber at $z=2.811$ in this spectrum. For the first time we detect HD (deuterated molecular hydrogen) in this system with a column density of $\log_{10}(N/\mathrm{cm^{-2}})=13.27 \pm 0.07$; HD is sensitive to variation in $μ$, and so we include it in our analysis. Using 76 H$_2$ and 7 HD transitions we constrain variation in $μ$ from the current laboratory value to be $Δμ/μ= (0.3\pm 3.2_\mathrm{stat} \pm 1.9_\mathrm{sys})\times 10^{-6}$, which is consistent with no cosmological variation in $μ$, as well as with previous results from other H$_2$/HD absorbers. The main sources of systematic uncertainty relate to accurate wavelength calibration of the spectra and the re-dispersion of multiple telescope exposures onto the one pixel grid.
description: 30 pages, 6 figures + 14 supplementary figures. Accepted for publication for MNRAS
Po�me en prose et conte po�tique dans La Jeune Belgique (1881-1897) et La Wallonie (1886-1892)
Creators: name: FONDACARO, GIUSEPPE
Publisher: name: Universit� degli studi di Genova
Year: 2018

description: Po�me en prose and conte po�tique in La Jeune Belgique (1881-1897) and La Wallonie
Phenomenological Theory of Boundary Friction in the Stick-Slip Mode
Creators: name: Lyashenko, I. A.
name: Khomenko, A. V.
name: Metlov, L. S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences
subject: J.2
subject: 37Exx, 80Axx, 82Cxx

description: A deterministic theory describing the melting of an ultrathin lubricant film between two atomically smooth solid surfaces has been developed. The lubricant state is described by introducing a parameter of excess volume that arises owing to the solid structure chaotization at its melting. The thermodynamic and shear kinds of melting are described consistently. The dependences of the stationary friction force on the lubricant temperature and the shear velocity of rubbing surfaces that move with respect to each other with a constant velocity have been analyzed. In the framework of a simple tribological model, the stick-slip mode of friction, when the lubricant periodically melts and solidifies, has been described. The influence of velocity, temperature, and load on the stick-slip friction has been analyzed. A qualitative comparison between the results obtained and experimental data has been carried out.
description: 9 pages, 6 figures, 40 references
On the role of different Skyrme forces and surface corrections in exotic cluster-decay
Creators: name: Dhiman, Narinder K.
name: Dutt, Ishwar
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present cluster decay studies of $^{56}$Ni$^*$ formed in heavy-ion collisions using different Skyrme forces. Our study reveals that different Skyrme forces do not alter the transfer structure of fractional yields significantly. The cluster decay half-lives of different clusters lies within \pm 10% for PCM and \pm 15% for UFM.
description: 13 pages,6 figures and 1 table; in press Pramana Journal of Physics (2010)
The transcriptional co-activator function of the LIM-domain protein nTrip6
Creators: name: Diefenbacher, Markus Elmar
Publisher: name: Karlsruhe
Year: 2009
Subjects: Trip6
nTrip6
LIM-domain proteins
dimerisation
coactivator
AP-1
Jun
Fos
GR
Glucocorticoid receptor
gene array cell line
BiFC
JNK
MAPK

description: An emerging class of proteins involved in the regulation of transcription are bridging factors. These proteins do not harbour any known co-activator function or domain, but are recruited to the promoter via a direct interaction with transcription factors. In this work I showed that nTrip6 acts as a selective co-activator for a subset of AP-1 dimers. Moreover, the interaction of AP-1 dimers with nTrip6 determines the ability of GR to transrepress these AP-1 dimers by tethering GR to the promoter.
The 2006 Outburst of the Magnetar CXOU J164710.2-455216
Creators: name: Woods, Peter M.
name: Kaspi, Victoria M.
name: Gavriil, Fotis P.
name: Airhart, Carol
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report on data obtained with the Chandra, XMM-Newton, Suzaku and Swift X-ray observatories, following the 2006 outburst of the Anomalous X-ray Pulsar CXO J164710.2-455216. We find no evidence for the very large glitch and rapid exponential decay as was reported previously for this source. We set a 3 sigma upper limit on any fractional frequency increase at the time of the outburst of Delta nu/nu < 1.5 x 10^{-5}. Our timing analysis, based on the longest time baseline yet, yields a spin-down rate for the pulsar that implies a surface dipolar magnetic field of ~9 x 10^{13} G, although this could be biased high by possible recovery from an undetected glitch. We also present an analysis of the source flux and spectral evolution, and find no evidence for long-term spectral relaxation post-outburst as was previously reported.
description: Submitted to ApJ
Post-procedural acute abdomen following percutaneous nephrolithotomy
Creators: name: Tonolini, Massimo
Publisher: name: EURORAD
Year: 2013
Subjects: subject: Kidney
subject: CT
subject: Imaging sequences
subject: Instrumentation
subject: Haemorrhage

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: female, 33 years
description: Clinical History: Young woman with known renal pelvis lithiasis and previous unsuccessful treatment with extracorporeal shockwave lithotripsy three years earlier, hospitalised to undergo percutaneous nephrolithotomy (PCNL). Progressive, intractable flank and abdomina... Final Diagnosis: Subcapsular, perinephric and retroperitoneal haemorrhage after percutaneous nephrolithotomy.
A Hardy-Moser-Trudinger inequality
Creators: name: Wang, Guofang
name: Ye, Dong
Publisher: name: arXiv
Year: 2010
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35J20 (35J60 47J30 58Jxx)

description: In this paper we obtain an inequality on the unit disc $B$ in the plane, which improves the classical Moser-Trudinger inequality and the classical Hardy inequality at the same time. Namely, there exists a constant $C_0>0$ such that \[ \int_B e^{\frac {4πu^2}{H(u)}} dx \le C_0 < \infty, \quad \forall\; u\in C^\infty_0(B),\] where $$H(u) := \int_B |\n u|^2 dx - \int_B \frac {u^2}{(1-|x|^2)^2} dx.$$ This inequality is a two dimensional analog of the Hardy-Sobolev-Maz'ya inequality in higher dimensions, which was recently intensively studied. We also prove that the supremum is achieved in a suitable function space, which is an analog of the celebrated result of Carleson-Chang for the Moser-Trudinger inequality.
description: 18 pages
Unsupervised tracking of time-evolving data streams and an application to short-term urban traffic flow forecasting
Creators: name: ABDULLATIF, AMR RASHAD AHMED
Publisher: name: Universit� degli studi di Genova
Year: 2018

description: I am indebted to many people for their help and support I receive during my Ph.D. study and research at DIBRIS-University of Genoa. First and foremost, I would like to express my sincere thanks to my supervisors Prof.Dr. Masulli, and Prof.Dr. Rovetta for the invaluable guidance, frequent meetings, and discussions, and the encouragement and support on my way of research. I thanks all the members of the DIBRIS for their support and kindness during my 4 years Ph.D. I would like also to acknowledge the contribution of the projects Piattaforma per la mobili� Urbana con Gestione delle INformazioni da sorgenti eterogenee (PLUG-IN) and COST Action IC1406 High Performance Modelling and Simulation for Big Data Applications (cHiPSet). Last and most importantly, I wish to thanks my family: my wife Shaimaa who stays with me through the joys and pains; my daughter and son whom gives me happiness every-day; and my parents for their constant love and encouragement.
Urosepsis: cross-sectional imaging findings and role
Creators: name: Tonolini, Massimo
Publisher: name: EURORAD
Year: 2013
Subjects: subject: Urinary Tract / Bladder
subject: CT
subject: MR
subject: Ultrasound
subject: Diagnostic procedure
subject: Infection

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 80 years
description: Clinical History: Elderly male patient with chronic congestive heart failure, diabetes, previous trans-urethral endoscopic resection for low-grade bladder urothelial carcinoma followed by intravesical chemotherapy, permanent Foley catheter, hospitalised because of haematur... Final Diagnosis: Renal abscesses in urosepsis.
Comparative Phytochemical and Pharmacological Properties of Commonly Available Tropical Green Seaweeds
Creators: name: Mani, Aswathi Elizabeth
name: Chakraborty, Kajal
name: Pananghat, Vijayagopal
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Plant Biology
subject: 60506 Virology

description: This study analyzed the ethyl acetate-methanol extracts of tropical green seaweeds for phytochemical indicators and antioxidant activities. Compositional analysis of the organic extracts of green seaweeds Ulva lactuca (formerly Ulva fasciata), Halimeda macroloba, Chaetomorpha linum and Chaetomorpha antennina identified the presence of phytoconstituents, such as total phenols, terpenoids, saponins and flavanoids. U. lactuca exhibited higher levels of total phenols (59.8 mg GAE/g), saponins (1.77 %), flavanoids (2.3 %), as well as greater 2, 2-diphenyl-1-picrylhydrazylradical radical quenching activity (DPPH.IC50 0.86 mg/mL). Extracts of U. lactuca and H. macrobola showed promising antimicrobial activities against Vibrio parahaemolyticus. Proton nuclear magnetic resonance fingerprint analyses of the solvent extracts showed that higher proton integrals were present in the downfield regions in U. lactuca, which could be responsible for lowering DPPH activity. The present work supports that the renewable green seaweed U. lactuca could be used to isolate prospective bioactive leads.
MRI findings in Fournier\'s gangrene
Creators: name: Shokry, Youstina
Publisher: name: EURORAD
Year: 2013
Subjects: subject: Pelvis
subject: Soft tissues / Skin
subject: MR
subject: Diagnostic procedure
subject: Tissue characterisation

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 30 years
description: Clinical History: A 30 year-old male patient presented to the emergency department with progressive painful swelling and marked local inflammation of the scrotum, and perineal region for 2 days. He has history of previous fistula operation one week before. Serum glucose le... Final Diagnosis: FournierÃ¢ÂÂs gangrene
Synthesis of novel ionisable lipids for the targeted delivery of siRNA
Creators: name: Panagopoulos, Dimitrios
Publisher: name: University of British Columbia
Year: 2016

description: RNA interference has been proven to be a powerful tool for gene probing and has also great therapeutic potential. In order for it to be clinically relevant, methods need to be developed for the targeted delivery of siRNA. Lipid nanoparticles (LNPs) have emerged as superior siRNA carrier agents with demonstrated efficacy in vivo. Such nanoparticles incorporate structurally novel lipids, the progenitor of which was conceived and first synthesized in this group. All such lipids bear an ionisable head group in the form of a tertiary amine. Protonation of this amino group is believed to promote a better association with the nucleic acid in the LNP construct. Extensive studies are currently underway in our laboratories to elucidate the structure-activity relationship of such lipids, and to produce lipids with better properties. In this work, we demonstrate the synthesis of five novel ionisable lipids, bearing different tertiary amine groups, for the purposes of siRNA encapsulation and delivery. Biological results showed one of them to be as effective as the benchmark lipid used in the field, whereas the others were not effective.
Fracture penis: Ultrasonography in diagnosis of an under-reported urological emergency
Creators: name: BASTI, RAM
Publisher: name: EURORAD
Year: 2013
Subjects: subject: Genital / Reproductive system male
subject: Ultrasound
subject: Diagnostic procedure
subject: Trauma

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 22 years
description: Clinical History: A 22-year-old man presented with acute-onset swelling of the penis, following an episode of bending the erect penis during sexual activity. A cracking sound was heard from the erect penis followed by pain and rapid detumescence following which he develope... Final Diagnosis: Fractured penis
Wilms tumor in a horseshoe kidney with intracaval extension
Creators: name: Kantarci, Mecit
Publisher: name: EURORAD
Year: 2013
Subjects: subject: Abdomen
subject: Kidney
subject: CT
subject: Contrast agent-intravenous
subject: Neoplasia

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 4 years
description: Clinical History: A four-year-old boy presented with abdominal pain and fever. On physical examination there was a mass in the left quadrant and midline of the abdomen. Final Diagnosis: Wilms tumor and intracaval extension
Electrohydrodynamic transport in compressible nanoporous packed beds
Creators: name: Schäfer, Bastian
Publisher: name: Karlsruhe
Year: 2010
Subjects: Colloids
Electrohydrodynamics
Agglomeration
Simulation
Experiments
Permeability
Packed beds
Filtration

description: In nanoporous packed beds, fluid flow and charge transport are closely interrelated due to the formation of the electrochemical double layers on the solid-liquid interfaces. This study presents an empirical model for the hydraulic permeability of packed beds and a capillary model for the interaction of mass and charge transport. A numerical investigation confirms the empirical model for the hydraulic permeability and gives further insight into the structure of the packed beds.
Mimicker of renal calculus: Milk of calcium in a renal cyst
Creators: name: Kantarci, Mecit
Publisher: name: EURORAD
Year: 2013
Subjects: subject: Abdomen
subject: CT
subject: Conventional radiography
subject: Image manipulation / Reconstruction
subject: Ultrasound
subject: Contrast agent-intravenous
subject: Diagnostic procedure
subject: Pathology

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: female, 57 years
description: Clinical History: A 57-year-old woman presented at our department with intermittent abdominal pain for a few months. No pathologic finding was detected in her physical and laboratory examinations. Final Diagnosis: Milk of calcium in a renal cyst
A Replica Inference Approach to Unsupervised Multi-Scale Image Segmentation
Creators: name: Hu, Dandan
name: Ronhovde, Peter
name: Nussinov, Zohar
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We apply a replica inference based Potts model method to unsupervised image segmentation on multiple scales. This approach was inspired by the statistical mechanics problem of "community detection" and its phase diagram. Specifically, the problem is cast as identifying tightly bound clusters ("communities" or "solutes") against a background or "solvent". Within our multiresolution approach, we compute information theory based correlations among multiple solutions ("replicas") of the same graph over a range of resolutions. Significant multiresolution structures are identified by replica correlations as manifest in information theory overlaps. With the aid of these correlations as well as thermodynamic measures, the phase diagram of the corresponding Potts model is analyzed both at zero and finite temperatures. Optimal parameters corresponding to a sensible unsupervised segmentation correspond to the "easy phase" of the Potts model. Our algorithm is fast and shown to be at least as accurate as the best algorithms to date and to be especially suited to the detection of camouflaged images.
description: 26 pages, 22 figures