cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Opinion leaders and complex sustainability issues: fostering response to climate change
Creators: name: Keys, Noni
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2012
Subjects: opinion leader
climate change
collective change
community organisation
influence

description: Making meaningful links between the global and local scales is an enduring challenge for behavioural change studies focused on sustainability. There is consensus that this is a complex issue and relying on the provision of information alone is insufficient to encourage the adoption of new practices by individuals. The role and strategies of the bearers of such information were investigated in this thesis to understand not only what is communicated, but who communicates between scales and levels of authority, and how. A sample of community opinion leaders was identified through nominations by members of community organisations in the Sunshine Coast region, Australia. Data for analysis was generated from these nominations and from semi-structured interviews with fifteen community opinion leaders. Thematic analysis was applied to investigate characteristics of the community opinion leaders and the strategies for influence they use. Argument analysis frameworks were used to analyse community opinion leaders' positions in relation to responding to climate change. Community opinion leaders try to influence change predominantly through existing social structures and power. Through their capacity to reach beyond the local to influence structures affecting the local they demonstrate the potential for enhanced engagement with sustainability issues that require structural, enduring, cross-scale societal transitions. Community opinion leaders' evaluations of the seriousness of climate change risk for their areas of community influence also indicate the nature of information that is lacking in the public debate about responding to climate change. The findings of this analysis highlight the need to develop targeted information that would allow community opinion leaders to assess the risks from climate change and to determine responses that support their community commitments. This study has shown that community opinion leaders enact their commitments to change by facilitating the development of knowledge and skills within their organisations, and building networks for the exchange of knowledge and influence with other community organisations and government agencies across scales. Such skills and approaches to influence are transferable between issue domains and as such, contribute to a community capacity for change.
Microfinance and socio-economic development: an integrated approach in Nepal
Creators: name: Paudyal, Ratna
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2018
Subjects: microfinance
socio-economic development
integrated microfinance
Nepal
poverty alleviation
social capital
health issues
illiteracy
lack of finance
income
social inclusion
poverty

description: This study investigated the perceptions of clients, social workers, and community members about clients' participation in an integrated microfinance program in order to assess the usefulness of integrating finance with medical treatment, training, and education. While microfinance is often used in developing countries as a poverty alleviation tool, many studies of microfinance programs question their effectiveness as a genuine means of alleviating poverty. A growing body of literature has more recently identified problems with microfinance brought about by the apparent misuse of loans by the finance clients, pointing to clients who have found themselves compelled to use the loan to fund necessary health care and other basic needs. Increasing evidence indicates that minimal support (finance only) is not enough to assist impoverished people because the causes of poverty are multidimensional and the clients need more than finance to break the cycle of poverty.
title: ¡Míranos!: Study Proposal and Information
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: subject: Latino
subject: urban
subject: proposal
subject: abstract
subject: information sheet
subject: multi-level intervention
subject: preschool
subject: development
subject: Head Start
subject: obesity prevention
subject: nutrition
subject: physical activity
subject: policy change

description: ¡Míranos! Look at Us, We Are Healthy! (¡Míranos!) is a participatory project, tailored to Latino preschool children and their parents, to promote the healthy development of predominantly Latino children in Head Start in San Antonio. The ¡Míranos! program includes center-based (policy changes, staff development, gross motor program and nutrition education) and home-based (parent engagement/education, home visits) interventions to address key enablers and barriers in obesity prevention in young children.
description: This record contains documents that the ¡Míranos! research team created to propose the study and provide further information about its design. This includes a study proposal, a study abstract with a list of aims, and a study information sheet.
The climate change mitigation potential of the waste sector
Creators: name: Vogt, Regine
name: Greeven-Derreza, Cassandra
name: Giegrich, Jürgen
Publisher: name: My University
Year: 2015
Subjects: subject: Klimaschutz
subject: Abfallwirtschaft
subject: OECD
subject: USA
subject: Ägypten
subject: climate protection
subject: waste management
subject: India
subject: Egypt
subject: CO2-mitigation cost
subject: Klima | Energie
subject: Climate | Energy

description: This study presents the greenhouse gas (GHG) mitigation potential of municipal solid waste (MSW) management in ⁠OECD⁠ countries as well as India and Egypt. Three detailed GHG balances for the USA, India, Egypt and one balance for the OECD countries are elaborated applying the life cycle assessment (LCA) method according to ISO 14040/14044 for waste management. For each balance the respective status quo is determined and compared with two scenarios to 2030. The methodology as well as the underlying data and assumptions were profoundly discussed at workshops with LCA experts and local stakeholders. A GHG calculation approach was developed, which uses harmonised emission factors to credit avoided emissions from material recycling. With regard to the status quo, the net results for the OECD countries, the USA, India and Egypt show that methane emissions from landfilling are the main contributor to the GHG burdens. Only OECD countries with little or no landfill of (organic) waste achieve a net credit (e.g. Japan). These credits are the more evident the higher recycling rates are and the more efficient energy recovery is. The findings of this study were presented in May 2014 at the environmental fair IFAT in Munich.
Emergency department visits during the 4/20 cannabis celebration
Creators: name: Staples, John
name: Merchant, Kate
name: Erdelyi, Shannon
name: Lund, Adam
name: Brubacher, Jeffrey
Publisher: name: BMJ Publishing Group
Year: 2022

description: BACKGROUND: In many cities, annual "4/20" cannabis festivals occur on April 20 and often feature synchronized consumption of cannabis at 4:20 p.m. The relationship between these events and demand for emergency medical services has not been systematically studied. METHODS: We conducted a population-based retrospective cohort study in Vancouver, Canada, using ten consecutive years of data (2009 to 2018) from six regional hospitals. The number of emergency department (ED) visits between 4:20 p.m. and 11:59 p.m. on April 20 were compared to the number of visits during identical time intervals on control days one week earlier and one week later (i.e. April 13 and April 27) using negative binomial regression. RESULTS: A total of 3,468 ED visits occurred on April 20 and 6,524 ED visits occurred on control days. A non-significant increase in all-cause ED visits was observed on April 20 (adjusted relative risk, 1.06; 95% CI, 1.00 - 1.12). April 20 was associated with a significant increase in ED visits among pre-specified subgroups including a five-fold increase in visits for substance misuse and a ten-fold increase in visits for intoxication. The hospital closest to the festival site experienced a clinically and statistically significant 17% (95% CI, 5.1% - 29.6%) relative increase in ED visits on April 20 compared to control days. INTERPRETATION: Substance use at annual "4/20" festivals may be associated with an increase in emergency department visits among key subgroups and at nearby hospitals. These findings may inform harm reduction initiatives and festival medical care service planning.
Combinatorial Utrophin A Activation in Muscle as a Therapeutic Strategy to Treat Duchenne Muscular Dystrophy
Creators: name: Ahmed, Aatika
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Utrophin A
Duchenne Muscular Dystrophy
Combinatorial Treatment
mdx

description: Duchenne Muscular Dystrophy (DMD) is an X-linked recessive neuromuscular disorder caused by mutations or deletions in the dystrophin gene. Utrophin up-regulation therapy is among the various therapeutic strategies that are being investigated to treat DMD. In this strategy utrophin, a dystrophin homologue, is up-regulated along the entire length of the sarcolemma to replace the absent dystrophin protein. Previous studies have revealed that utrophin A expression can be controlled by various transcriptional, post-transcriptional and translational mechanisms and pharmacological modulation of these pathways can stimulate its expression in muscle. In the present study we screened several FDA approved and natural pharmacological compounds that can potentially activate utrophin A expression in muscle. We found that AICAR (AMPK activator) and heparin (p38 activator) were most effective in stimulating utrophin A expression in our C2C12 muscle cell system. Next, we analyzed the effect of combining these activators on utrophin A expression in muscle cells and preclinical mdx mouse model of DMD. Our findings revealed that combinatorial treatment of AICAR and heparin instigated an additive effect on utrophin A expression both in C2C12 muscle cells and mdx mice. Further characterization of treated mdx mice revealed that combinatorial treatment of AICAR and heparin caused improvements in the dystrophic phenotype as indicated by decreased central nucleation, decreased fiber size variability and improved sarcolemmal integrity in dystrophic muscle. Together these findings established that combinatorial treatment of AICAR and heparin ameliorates the dystrophic phenotype in mdx mice and may serve as an effective therapeutic strategy for DMD.
Optimising Markets for Moreton Bay Fresh Prawns Through Supply Chain Management
Creators: name: Byrom, David J
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2014
Subjects: Moreton Bay
prawns
seafood
value chain analysis
supply chain management

description: The seafood industry in Australia is in serious decline with more than 70% of all seafood imported. The prawn industry in particular is suffering from intense competition from farmed imports, rising fuel prices and stagnant prices. In an attempt to reverse the fortunes or slow the demise of the commercial prawn fishery, Supply Chain Management has been suggested as a possible tool to assist in improving profitability and viability. Supply chain research has been seen to improve efficiencies and effectiveness in other agri-food supply chains but has yet to be applied or documented in the context of the Australian fresh seafood industry. The research question addressed by this study is: What are the barriers to and opportunities for improving profitability in a fresh seafood supply chain in Australia?
Smart Grid Applications Using Sensor Web Services
Creators: name: Asad, Omar
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Wireless Sensor Networks
Smart Grid
Energy Management
Web Services

description: Sensor network web services have recently emerged as promising tools to provide remote management, data collection and querying capabilities for sensor networks. They can be utilized in a large number of elds among which Demand-Side Energy Management (DSEM) is an important application area that has become possible with the smart electrical power grid. DSEM applications generally aim to reduce the cost and the amount of power consumption. In the traditional power grid, DSEM has not been implemented widely due to the large number of households and lack of ne-grained automation tools. However by employing intelligent devices and implementing communication infrastructure among these devices, the smart grid will renovate the existing power grid and it will enable a wide variety of DSEM applications. In this thesis, we analyze various DSEM scenarios that become available with sensor network web services. We assume a smart home with a Wireless Sensor Network (WSN) where the sensors are mounted on the appliances and they are able to run web services. The web server retrieves data from the appliances via the web services running on the sensor nodes. These data can be stored in a database after processing, where the database can be accessed by the utility, as well as the inhabitants of the smart home. We showthat our implementation is e cient in terms of running time. Moreover, the message sizes and the implementation code is quite small which makes it suitable for the memory-limited sensor nodes. Furthermore, we show the application scenarios introduced in the thesis provide energy saving for the smart home.
Adverse Health Outcomes Among Organ Replacement Patients in Canada
Creators: name: Gheorghe, Mihaela
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: transplantation
cancer
mortality
major causes of death
Canada
cancer incidence
neoplasm

description: BACKGROUND: Organ transplantation is one of the best modalities for treating fatal organ failure. Despite the success of this procedure, an increasing incidence of cancer in this population has drawn the attention of public health officials in recent years. OBJECTIVES: The overall objective of this study is to conduct a detailed examination of adverse health outcomes among Canadian organ transplant recipients, with an emphasis on cancer incidence and mortality. METHODS: This project employed a retrospective cohort follow-up study design, whereby Canadian Organ Replacement Registry records were linked to the Canadian Mortality Database and the Canadian Cancer Registry Database. The study population consisted of more than 16,000 solid organ transplant recipients registered between January 1, 1981 and December 31, 1998. This study was designed to assess the risks of developing cancer, overall and site-specific, in transplant recipients in comparison to the general Canadian population using Standardized Incidence Ratios (SIR), Standardized Mortality Ratios (SMR), and Proportionate Mortality Ratios (PMR). In addition, Cox and logistic models were used to assess the effects of various risk factors on cancer incidence and mortality in transplant sub-populations, while cumulative incidence was used to study the patient survival pattern. Lastly, Population Attributable Risk (PAR) was used to quantify the impact of organ transplantation on cancer incidence and mortality. RESULTS: Among major causes of death, the highest PMRs are due to genitourinary diseases, followed by endocrine, nutritional and metabolic diseases, and infectious diseases. SIRs indicate that cancer incidence and mortality were relatively lower than that observed for other major causes of death, and slightly higher than that observed in the general Canadian population. Lastly, logistic regression results indicate that age, year of surgery, and smoking status were significant risk factors in mortality due to all causes, while the Cox regression model shows that age, sex and year of surgery were significant risk factors for cancer incidence. Overall, the PAR in this cohort was very minimal, indicating that the risk in mortality and cancer incidence due to organ transplantation is negligible. CONCLUSION: Life threatening diseases such as those of the genitourinary system, as well as endocrine, nutritional and metabolic diseases and infectious diseases are leading causes of death. Future research should be directed at ways of reducing incidence and subsequent mortality due to these causes.
An Exegetical Investigation into the Life and Crimes of Jack the Ripper, explored through the Creative Artefact: Return to Whitechapel: The Ripper’s Knife
Creators: name: Jacobs, Dean A
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2014
Subjects: hyperrealistic digital illustration

description: Set in the 1950s, my creative artefact, Return to Whitechapel: The Ripper's Knife, is an illustrated sequel to my 2010 novel, The Streets of Whitechapel, which explored the 1888 crime spree of Jack the Ripper. Return to Whitechapel: The Ripper's Knife seeks to analyse what became of Jack the Ripper post 1888, and theseries of events that led him back to the streets of Whitechapel some years later. The confession-based narrative attempts to establish a plausible life journey for James Collins, and his doppelganger Jack the Ripper, as they return to the scene of the crimes to attempt to capture a copycat emulating the 1888 murders. The 13 Hyperrealistic illustrations accompanying the narrative represent James' psychic recollections of his life journey post his 1888 atrocities. The exegetical component of this Doctorate of Creative Arts (Creative Writing) provides an exploration into the life and crimes of my novel's protagonist, James Collins, aka Jack the Ripper, and the implications of that research when applied to my creative artefact. The exegesis further provides an investigation into the interplay between word and image in the illustrated book, the use of Hyperrealistic illustrations and their contribution to the interpretation of the print text within an illustrated novel.
Supplementary document for Polarimetric data-based model for tissue recognition - 5301649.pdf
Creators: name: Rodríguez, Carla
name: Van Eeckhout, Albert
name: Ferrer, Laia
name: Garcia-Caurel, Enrique
name: González-Arnay, Emilio
name: Coloma, Juan Campos
name: Lizana, Angel
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Additional information for the main manuscript: complete image Mueller polarimeter description; statistical analysis; predictive model construction; and tissue recognition through binary logistic model examples.
Sexual development in the male Eastern Spiny Lobster (Sagmariasus verreauxi): the sex determination mechanism and ongoing regulation of sexual differentiation
Creators: name: Chandler, Jennifer
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2017
Subjects: sexual development
crustacean
Dmrt
sex determination
Spiny Lobster

description: The role of the insulin-like androgenic gland hormone (IAG) has been extensively characterised in the decapod Crustacea as being that responsible for male sexual differentiation and maturation. In particular IAG has been of significant interest due to its application in the production of monosex population culture in commercially important decapod species. The Eastern spiny lobster, Sagmariasus verreauxi, endemic to south- east Australia, is one such commercially valued species, with a growing potential in aquaculture. This work has therefore explored the regulation of male sexual development in S. verreauxi, both to aid its own culture practices and as a model for the Order. Throughout, we have employed the de novo assembled S. verreauxi transcriptome, undertaking a synergy of broad-scale and targeted transcriptomic methods to generate a more cohesive understanding of the regulation of male sexual development.
Utilizing Blockchain to Measure Privacy and Security in a Healthcare System: Jordan Healthcare System as a Case Study
Creators: name: aldalabeeh, ahmad
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 461201
subject: Automated software engineering

description: Blockchain technology has emerged as a transformative innovation across multiple sectors, including finance, healthcare, agriculture, and real estate. Despite its widespread adoption, the healthcare system in Jordan has not yet fully leveraged blockchain for patient information storage, encountering significant implementation challenges.
This study aims to identify the obstacles faced by physicians in verifying patient conditions and accessing medical histories, as well as the limitations inherent in current off-chain systems. By examining these issues, the study seeks to propose solutions to improve the efficiency of the healthcare system.
Healthcare professionals and software developers from both government and private hospitals, as well as medical laboratories, participated in this study. Data was collected from 100 participants and analyzed to derive conclusions and insights.
The primary finding suggests that the adoption of blockchain technology for storing patient healthcare records and electronic health records can greatly enhance the security, reliability, integrity, and privacy of patient data. The study advocates for the integration of health systems from private and government hospitals into a unified, independent system that shares a common database while preserving individual hospital information.
The study emphasizes blockchain's capability to ensure data security both on-chain and off-chain, thereby reducing the risks of data loss and forgery. It highlights the challenges physicians face in verifying patient cases and retrieving medical histories, stressing the necessity for streamlined processes to manage patient data more efficiently.
These results provide valuable insights for healthcare professionals, software developers, and organizations, highlighting the potential benefits of blockchain technology in addressing security and privacy concerns within the healthcare sector.
Dynamic Composition and Management of Virtual Devices for Ad Hoc Multimedia Service Delivery
Creators: name: Karmouch, Eric
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Pervasive computing
Location-dependent and sensitive
Multimedia applications
Algorithm/protocol design and analysis
Mobile environments
Constraint satisfaction

description: Pervasive computing implies the invisibility of the technology involved in providing ubiquity, such that technology is integrated into the environment and non-intrusive. In such a manner, computing and networking resources become diffused into physical environments, enabling users to exploit their provided functionalities such that functionality is distributed, enabling it to be controlled, monitored, managed, and extended beyond what it was initially designed to do. Moreover, computer awareness moves towards user-centricity, whereby systems seamlessly adapt to the characteristics, preferences, and current situations of users and their respective surrounding environments. Users exploit such functionalities in the form of a virtual device, whereby a collection of heterogeneous devices in the vicinity of the user are behaving as one single homogeneous device for the benefit of the user in solving some given task. This dissertation investigates the problem of dynamic composition and management of virtual devices for ad hoc multimedia service delivery and proposes an autonomous policy driven framework for virtual device management. The framework consists of a hierarchical structure of distributed elements, including autonomic elements, all working towards the self-management of virtual devices. The research presented in this dissertation addresses the functionalities of these components. More specifically, contributions are made towards the autonomous management of virtual devices, moving away from infrastructure based schemes with heavy user involvement to decentralized and zero touch (i.e., no user involvement) solutions. In doing so, the components and methodology behind a policy-driven autonomous framework for the dynamic discovery, selection, and composition of multimodal multi-device services are presented. The framework operates in an ad hoc network setting and introduces a Service Overlay Network (SON) based definition of a virtual device. Furthermore, device and service discovery, composition, integration, and adaptation schemes are designed for Mobile Ad hoc Network Environments (MANETs) enabling users to generate, on-the-fly, complex strong specific systems, embedding in a distributed manner, QoS models providing compositions that form the best possible virtual device at the time of need. Experimental studies are presented to demonstrate the performance of the proposed schemes.
British Petroleum America et la marée noire : cartographie stratégique de crise
Creators: name: Benoit, Laurent
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: étude de cas
communication de crise
stratégies de communication
Image Repair Theory
Théorie de la restauration de l’image
réputation
Récits de l’entreprise
BP
Marée noire

description: Notre recherche qualitative, une étude de cas en communication de crise, dresse le portrait de la marée noire dans le golfe du Mexique durant l’été 2010. La recherche est ancrée sur le modèle de l’Image Repair Theory (IRT) de W.L. Benoit, bonifié de contributions d’autres auteurs, afin d’étudier les stratégies de communication de crise utilisées par British Petroleum America (BP). En scrutant la version Web de quotidiens d’information et le site Internet de BP, nous avons identifié 176 citations officielles que nous avons cataloguées grâce à une analyse de contenu basée sur la Théorie de la narration de Nicole D’Almeida. La description de ce cas réel et l’analyse des stratégies de communication de crise de BP confirment l’adaptabilité de l’IRT bonifiée (IRTB) aux conditions de l’étude et au contexte propre à la crise. L’IRTB a facilité l’interprétation et l’indexation des six stratégies de communication de crise utilisées par BP afin de défendre, promouvoir ou réparer sa réputation.
Mast cell deficiency limits the development of chronic rhinosinusitis in mice
Creators: name: Jania, C.M.
name: Graham, S.M.
name: Tilley, S.L.
name: Senior, B.A.
name: Doerschuk, C.M.
name: Chason, K.D.
name: Naselsky, W.C.
name: Huang, J.J.
name: Hua, X.
Publisher: name: SAGE Publications Inc.
Year: 2016

description: Background: Chronic rhinosinusitis (CRS) is one of the most common chronic diseases in adults in both developing and developed countries. The etiology and pathogenesis of CRS remain poorly understood, and the disease is refractory to therapy in many patients. Mast cell activation has been demonstrated in the sinonasal mucosa of patients with CRS; however, the specific contribution of mast cells to the development and pathogenesis of this disease has not been established. Objective: The objective of this study was to investigate the role of mast cells in the development of CRS. Methods: C57BL/6 wild-type and C57BL/6-KitW-sh/W-sh mast cell-deficient mice were immunized by intraperitoneal allergen injection and subsequent chronic low dose intranasal allergen challenges. The sinonasal phenotypes of these groups were then evaluated and compared to saline-treated controls using radiologic, histologic, and immunologic methods. Results: Wild-type mice exposed to chronic intranasal allergen developed many features seen in human CRS, including mucosal thickening, cystic changes, polyp development, eosinophilia, goblet cell hyperplasia, and mast cell activation. In contrast, sinonasal pathology was significantly attenuated in mast cell-deficient mice subjected to the same chronic allergen protocol. Specifically, tissue eosinophilia and goblet cell hyperplasia were reduced by approximately 50% compared to wild-type levels. Surprisingly, none of the mast cell-deficient mice subjected to chronic allergen challenge developed cystic changes or polypoid changes in the nose or sinuses. Conclusions: These data identify a critical role for mast cells in the development of many features of a mouse model of eosinophilic CRS, suggesting that therapeutic strategies targeting mast cells be examined in humans afflicted with this disease.
Understanding household adaptive capacity: case studies from coastal Australia
Creators: name: Elrick-Barr, Carmen
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2016
Subjects: adapt
household
risk
perception
climate change
coast
Australia

description: The effects of climate change, including rising mean sea level, pose significant challenges for coastal communities and are argued to require a collective adaptive response to address the impacts. Consequently, the Australian government, in its adaptation and hazard management policy, has assigned households shared responsibility for adapting to the impacts of climate change. Further, it is acknowledged that information regarding the needs, strengths and vulnerabilities of communities is required to inform capacity development strategies. Yet despite a policy emphasis on household capacity for adaptation, research on the capacity of coastal households has been limited; with studies more frequently quantifying projected impacts and evaluating the capacity of local government authorities to respond. This study addresses this gap by contributing to an understanding of the nature of household adaptive capacity in Australian coastal communities. Through mixed method case-study research in two peri-urban coastal communities, risk perceptions, perceived capability, capacity needs and current responses to manage climate change and its associated hazards are uncovered. The results indicate that Australian coastal households are coping with climate hazards and mitigating greenhouse gas (GHG) emissions. Adaptation to the impacts of climate change is limited. The characteristics associated with action (e.g. risk perception, past experience, home ownership) vary based on the type of action taken (i.e. mitigating GHG emissions, lobbying for change or impact orientated adaptive responses). Perceptions that a hazard is a low risk, perceptions of adequate capability for familiar hazards, and perceptions of limited household responsibility beyond coping are barriers to adaptive action. These barriers are influenced by: (i) past experience with climate hazards; (ii) the efficacy of coping strategies previously deployed in response to experienced hazards; (iii) social narratives of capability to prepare for and respond to climate hazards; (iv) the availability of external support services (e.g. State Emergency Services); and (v) acceptance of climate-related risks. However, a willingness to take responsibility for managing climate hazards and requests for further information on household exposure to risk and strategies to adapt provide opportunities to build capacity for climate change adaptation. The findings demonstrate that relying on generic determinants of capacity to identify those vulnerable and evaluate their capability to adapt provides only a partial understanding of the barriers to and capacity for adaptation-perceptions at the household scale are critical.
Pulmonary alveolar proteinosis and macrophage transplantation
Creators: name: Doerschuk, C.M.
Publisher: name: Massachussetts Medical Society
Year: 2015

description: Macrophages are highly variable, and their ontogeny and functions depend on the particular organ in which they reside and on any ongoing disease processes.  Lung  macrophages  are  critically  important to lung function, and knowledge of their ontogeny and phenotypes is rapidly expanding.  Lung macrophages are present within the alveolar spaces and in the airway wall and lumen. Airway macrophages represent both alveolar macrophages that are on their way along the mucociliary escalator toward the nasopharynx and other distinct populations of macrophages, which may have their own ontogeny and function. In healthy lungs, the overarching functions of macrophages include serving as a host-defense surveillance system that protects the lungs, modulating (often dampening) inflammatory and immune responses, and monitoring and regulating the surfactant layer, which is critical to maintaining a low surface tension and enabling the opening of alveoli with each breath.
Microfabrication of Plasmonic Biosensors in CYTOP Integrating a Thin SiO2 Diffusion and Etch-barrier Layer
Creators: name: Hanif, Raza
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Plasmonics
Long Range Surface Plasmon Polariton
Microfabrication
Silicon Dioxide (SiO2)
O2 plasma RIE etch
e-beam evaporation
Micro-fluidic channels
Optical cut-back measurements
CYTOP

description: A novel process for the fabrication of Long Range Surface Plasmon Polariton (LRSPP) waveguide based biosensors is presented herein. The structure of the biosensor is comprised of Au stripe waveguide devices embedded in thick CYTOP claddings with a SiO2 solvent diffusion barrier and etch-stop layer. The SiO2 layer is introduced to improve the end quality of Au waveguide structures, which previously deformed during the deposit of the upper cladding process and to limit the over-etching of CYTOP to create micro-fluidic channels. The E-beam evaporation method is adapted to deposit a thin SiO2 on the bottom cladding of CYTOP. A new micro-fluidic design pattern is introduced. Micro-fluidic channels were created on selective Au waveguides through O2 plasma etching. The presented data and figures are refractive index measurements of different materials, thickness measurements, microscope images, and AFM images. Optical power cutback measurements were performed on fully CYTOP-cladded symmetric LRSPP waveguides. The end-fire coupling method was used to excite LRSPP modes with cleaved polarization maintaining (PM) fibre. The measured mode power attenuation (MPA) was 6.7 dB/mm after using index-matched liquid at input and output fibre-waveguide interfaces. The results were compared with the theoretical calculations and simulations. Poor coupling efficiency and scattering due to the SiO2 are suspected for off-target measurements.
Pulmonary alveolar proteinosis - Is host defense awry?
Creators: name: Doerschuk, C.M.
Publisher: name: Massachussetts Medical Society
Year: 2007

description: Pulmonary alveolar proteinosis is a rare disorder caused by abundant accumulation of surfactant-derived components in the lungs. The incidence is estimated to be 0.36 case per million population, and the prevalence, 3.70 cases per million. About 500 cases have been recorded in the literature.
title: ¡Míranos!: Training Materials
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: subject: peer educator
subject: training manual
subject: Latino
subject: urban
subject: multi-level intervention
subject: preschool
subject: development
subject: Head Start
subject: obesity prevention
subject: nutrition
subject: physical activity
subject: policy change

description: ¡Míranos! Look at Us, We Are Healthy! (¡Míranos!) is a participatory project, tailored to Latino preschool children and their parents, to promote the healthy development of predominantly Latino children in Head Start in San Antonio. The ¡Míranos! program includes center-based (policy changes, staff development, gross motor program and nutrition education) and home-based (parent engagement/education, home visits) interventions to address key enablers and barriers in obesity prevention in young children.
description: This record contains materials used to train peer educators for the ¡Míranos! study. This includes a digital training manual for center-based intervention, a peer educator guide, a guide for training peer educators, and a digital training manual for home-based intervention.
Neutrophil cytoskeletal rearrangements during capillary sequestration in bacterial pneumonia in rats
Creators: name: Kondo, R.
name: Doerschuk, C.M.
name: Yoshida, K.
name: Wang, Q.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Rationale: Neutrophils accumulate in pulmonary capillaries during acute inflammation. Initial events in injury recognition and sequestration do not occur through selectin-mediated rolling. Cytoskeletal rearrangements, as assessed by submembrane F-actin rims, result in poorly deformable neutrophils that may not pass through capillaries. Objective: To test the hypothesis that neutrophils sequestering during pneumonia contain F-actin rims and to determine the roles of CD11/CD18, L-selectin expression, and neutrophil-platelet adhesion in neutrophil sequestration. Methods: Neutrophils were compared in blood obtained simultaneously from venous and arterial sites before and 4 h after instillation of Streptococcus pneumoniae or Escherichia coli in rats. Measurements and Main Results: At 4 h of pneumonia, the number of neutrophils was greater in the venous blood entering the lungs than in the arterial blood leaving the lungs, indicating that neutrophil sequestration was occurring. More neutrophils entering the lungs contained F-actin rims than did neutrophils exiting, and the venous-arterial difference in F-actin-rimmed neutrophil counts completely accounted for sequestration. In E. coli pneumonia, in which neutrophil adhesion is mediated by CD11/CD18, CD18 blockade 15 min before blood samples were obtained did not prevent this sequestration of F-actin-rimmed neutrophils. Neutrophils expressing high or low levels of L-selectin or of neutrophils that bound platelets while circulating did not preferentially sequester. Conclusions: Neutrophils with cytoskeletal rearrangements preferentially sequester within the lungs during pneumonia, and this sequestration is not due to CD11/CD18-mediated adhesion, L-selectin expression, or platelet adhesion to neutrophils, suggesting that cytoskeletal rearrangements result in sequestration of neutrophils.
Serious harms with long-term PPI use in older adults
Creators: name: Therapeutics Initiative (University Of British Columbia)
Publisher: name: The University of British Columbia
Year: 2023

description: Therapeutics Letter 126 considers serious harms with long-term proton pump inhibitor use in older adults. Conclusions: Observational studies have identified signals of serious harms from long-term PPI exposure, including an increased risk of death. Even large RCTs may not detect these, if exposure or follow-up are insufficiently long. The COMPASS trial findings are not inconsistent with contemporaneous findings from observational studies. Clinicians and patients can reverse the relentless expansion of long-term PPI exposure by reviewing indications and considering potential harms as well as benefits.
Attenuation of endotoxin-induced acute lung injury by the Rho associated kinase inhibitor, Y-27632
Creators: name: Koh, H.
name: Ogawa, Y.
name: Ishii, Y.
name: Tasaka, S.
name: Doerschuk, C.M.
name: Ishizaka, A.
name: Yamada, W.
name: Yamaguchi, K.
name: Hasegawa, N.
name: Shimizu, M.
name: Richer, S.E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: A small GTPase, Rho, plays key roles in cell adhesion, motility, and contraction after stimulation. Among Rho effectors isolated, the family of Rho-associated coiled-coil-forming protein kinases (ROCK) is implicated in Rho-mediated cell adhesion and smooth muscle contraction. The effect of a specific inhibitor of ROCK, Y-27632, was evaluated in a murine model of acute lung injury induced by intravenous injection of Escherichia coli endotoxin (lipopolysaccharide [LPS]). Lung edema was evaluated by measuring extravascular leakage of radio-labeled serum albumin, and neutrophil emigration into the lung parenchyma by morphometric observation and measuring myeloperoxidase activity. Pretreatment with Y-27632 attenuated both lung edema and neutrophil emigration after LPS. We also measured albumin transfer through cultured endothelial cell monolayers on a porous filter. Tumor necrosis factor-α significantly increased albumin transfer, which was attenuated by pretreatment with Y-27632. Fluorescence microscopy revealed that morphologic changes in endothelial cells induced by tumor necrosis factor-α were inhibited by Y-27632. In contrast, the increased fraction of neutrophils with polymerized actin after formyl-methionyl-leucyl-phenylalanine was not altered by Y-27632. These data suggest that ROCK may play an important role in the pathogenesis of LPS-induced lung injury and that ROCK inhibition could attenuate cytoskeletal rearrangement of endothelial cells, leading to decreased neutrophil emigration into the lung parenchyma.
title: Implementation of Nationally Determined Contributions
title: Zehn Länderstudien zu einer ambitionierteren Klimapolitik
titleType: AlternativeTitle
title: Indonesia Country Report
titleType: AlternativeTitle
Creators: name: Mersmann, Florian
name: Wehnert, Timon
name: Andreeva, Tatiana
Publisher: name: My University
Year: 2017
Subjects: subject: Klimarahmenkonvention
subject: LULUCF [Kyoto-Protokoll]
subject: UNFCCC
subject: LULUCF
subject: mitigation potential
subject: Indonesia
subject: Nationally Determined Contribution
subject: Klima | Energie
subject: Climate | Energy

description: The study analyses the country background, emissions trends, ongoing activities and barriers relating to the implementation of the Nationally Determined Contribution (NDC) of Indonesia under the ⁠UNFCCC⁠. A special emphasis is laid on further mitigation potentials. Fields of mitigation assessed are land use, land use change and forestry (⁠LULUCF⁠) governance and monitoring as well as electricity demand and generation. A chapter is dedicated to the ongoing and planned increase in coal use – contrary to mitigation ambition in other fields – including an analysis of the economic role and local impacts of coal.
Supplementary document for Polarimetric data-based model for tissue recognition - 5301649.pdf
Creators: name: Rodríguez, Carla
name: Van Eeckhout, Albert
name: Ferrer, Laia
name: Garcia-Caurel, Enrique
name: González-Arnay, Emilio
name: Coloma, Juan Campos
name: Lizana, Angel
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Additional information for the main manuscript: complete image Mueller polarimeter description; statistical analysis; predictive model construction; and tissue recognition through binary logistic model examples.
Neutrophils in Innate Immunity
Creators: name: Mizgerd, J.P.
name: Doerschuk, C.M.
name: Wang, Q.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Neutrophils are an important component of innate immunity in the lungs. During bacterial pneumonia, neutrophils are recruited from the capillaries of the pulmonary circulation in the gas-exchanging regions of the lungs. This process requires the coordinated activation of many cells within the lungs, including neutrophils and capillary endothelial cells. Cellular activation during innate immune responses is mediated in part by tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-1-initiated signaling through their receptors, activation of nuclear factor kappa B (NF-κB) and downstream gene transcription, endothelial cell signaling initiated by neutrophil adherence to intercellular adhesion molecule (ICAM)-1, and binding of leukocyte adhesion molecules to cellular and matrix ligands. These events are essential to effective host defense during pneumonia.
Permeable Pavements: Investigation on the Infiltration Rates and Testing Methods of Permeable Pavements
Creators: name: Walter, Jayden
Publisher: name: University of the Sunshine Coast, Queensland
Year: 2014

description: Water sensitive urban design (WSUD) is a term used in Australia to describe the engineering design approach to the urban water cycle, including stormwater, to ultimately minimise environmental degradation. There are many common WSUD practices that aim to minimise environmental degradation as well as improving the aesthetic and recreational appeal to the area and one of these is permeable pavements. Permeable pavement systems are an alternative to impervious pavements and they allow the infiltration of rainwater to be stored in underground reservoirs or be filtered through the soil to ultimately recharge the water table and limit the amount of water runoff. Common applications of permeable systems include residential driveways, car parks, pedestrian walkways, and slope stabilisation. The permeability of a pavement is governed by the infiltration rate of the system. This infiltration rate is dependant upon many critical factors including the location, age, traffic load, and maintenance. Little research has been conducted on the maintenance of permeable pavements and this has led to many councils and developers not maintaining the pavement properly or at all. This research sets out to come up with an innovative method of testing a permeable pavement to determine whether or not the permeable pavement requires maintenance. This method will need to be simple, fast, and cheap to perform, to appeal to local councils and government bodies as a solution to the maintenance problem. This method has been the named the storm water infiltration field test, for the purposes of this report.
Open Platform Semi-Passive Ultra High Frenquency Radio Frequency Identi
Creators: name: Li, Tzu Hao
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: RFID
UHF
Open Platform
EPCglobal C1 G2

description: Radio frequency identi cation (RFID) is a rapidly emerging technology that enables au- tomatic remote identi cation of objects. Passive and semi-passive RFID systems can be distinguished from other forms of wireless systems, because the RFID tags (transponders) communicate by way of backscatter. In addition, passive tags derive their energy from the RF energy emitted by the reader. RFID technology can provide a fully automated data capture and analysis system. Compared to a passive RFID system, an open platform semi-passive UHF RFID tag can provide identi cation, security, low-power (compared to a wireless sensor net- work(WSN)), medium range and medium processing speed. However, the eld of semi- passive RFID is still under development, and has yet there are no open development platforms available. This thesis develops a prototype of a semi-passive UHF RFID tag that is compatible with the leading UHF RFID standard EPCglobal Gen 2 Class 1. I alsot has the exible I2C and analog digital converter(ADC) interface, which allows the additional of external analog and digital sensors. The sensor data can be read by microcontroller and stored at memory. Standard reader can get sensor data by sending QUERY and READ command to tag. Test results of our open platform semi-passive UHF RFID tag demonstrated that it can achieve a read rate above 50% when an open platform semi-passive UHF RFID tag is placed four meters from the reader antenna and the reader output power is set to 21 dBm. In addition, the proposed semi-passive open platform RFID tag consumes very little power (4.9 mA in 2V with system frequency set to 8MHz).
Implementation of provably stable MaxNet
Creators: name: Suchara, Martin
name: Andrew, Lachlan L. H.
name: Witt, Ryan
name: Jacobsson, Krister
name: Wydrowski, Bartek P.
name: Low, Steven H.
Publisher: name: Swinburne
Year: 2024

description: MaxNet TCP is a congestion control protocol that uses explicit multi-bit signalling from routers to achieve desirable properties such as high throughput and low latency. In this paper we present an implementation of an extended version of MaxNet. Our contributions are threefold. First, we extend the original algorithm to give both provable stability and rate fairness. Second, we introduce the MaxStart algorithm which allows new MaxNet connections to reach their fair rates quickly. Third, we provide a Linux kernel implementation of the protocol. With no overhead but 24-bit price signals, our implementation scales from 32 bit/s to 1 peta-bit/s with a 0.001% rate accuracy. We confirm the theoretically predicted properties by performing a range of experiments at speeds up to 1 Gbit/sec and delays up to 180 ms on the WAN-in-Lab facility.