cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Experimental quantum cosmology in time-dependent optical media
Creators: name: Westerberg, N.
name: Cacciatori, S.
name: Belgiorno, F.
name: Piazza, F. Dalla
name: Faccio, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is possible to construct artificial spacetime geometries for light by using intense laser pulses that modify the spatiotemporal properties of an optical medium. Here we theoretically investigate experimental possibilities for studying spacetime metrics of the form $\textrm{d}s^2=c^2\textrm{d}t^2-η(t)^2\textrm{d}x^2$. By tailoring the laser pulse shape and medium properties, it is possible to create a refractive index variation $n=n(t)$ that can be identified with $η(t)$. Starting from a perturbative solution to a generalised Hopfield model for the medium described by an $n=n(t)$ we provide estimates for the number of photons generated by the time-dependent spacetime. The simplest example is that of a uniformly varying $η(t)$ that therefore describes the Robertson-Walker metric, i.e. a cosmological expansion. The number of photon pairs generated in experimentally feasible conditions appears to be extremely small. However, large photon production can be obtained by periodically modulating the medium and thus resorting to a resonant enhancement similar to that observed in the dynamical Casimir effect. Curiously, the spacetime metric in this case closely resembles that of a gravitational wave. Motivated by this analogy we show that a periodic gravitational wave can indeed act as an amplifier for photons. The emission for an actual gravitational wave will be very weak but should be readily observable in the laboratory analogue.
description: Version accepted fro publication in New Journal of Physics
Bulletin der Heimatkundlichen Vereinigung Furttal, Nr. 62 (Dezember 2016)
Creators: name: (:Unkn) Unknown
Publisher: name: Zentralbibliothek Zürich
Year: 2016
Subjects: subject: 900 Geschichte und Geografie
subject: Furttal
subject: Heimatkundliche Vereinigung Furttal
subject: Verein
subject: Heimatkunde

description: Mit einer Jahreschronik für das Furttal 2016
On curves with nonnegative torsion
Creators: name: Bray, Hubert L.
name: Jauregui, Jeffrey L.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A04

description: We provide new results and new proofs of results about the torsion of curves in $\mathbb{R}^3$. Let $γ$ be a smooth curve in $\mathbb{R}^3$ that is the graph over a simple closed curve in $\mathbb{R}^2$ with positive curvature. We give a new proof that if $γ$ has nonnegative (or nonpositive) torsion, then $γ$ has zero torsion and hence lies in a plane. Additionally, we prove the new result that a simple closed plane curve, without any assumption on its curvature, cannot be perturbed to a closed space curve of constant nonzero torsion. We also prove similar statements for curves in Lorentzian $\mathbb{R}^{2,1}$ which are related to important open questions about time flat surfaces in spacetimes and mass in general relativity.
description: 13 pages, 7 figures; references added in second version
title: Retrograde procedural memory in Parkinson’s disease: a cross-sectional, case-control study
Creators: name: Laure PAULY
name: Claire PAULY
name: Maxime HANSEN
name: Valerie E. SCHRÖDER
name: Armin RAUSCHENBERGER
name: Anja K. LEIST
name: Rejko KRÜGER
Publisher: name: LCSB
Year: 2021

description: Background: The analysis of the procedural memory is particularly relevant in neurodegenerative disorders like Parkinson’s disease, due to the central role of the basal ganglia in procedural memory. It has been shown that anterograde procedural memory, the ability to learn a new skill, is impaired in Parkinson’s disease. However, retrograde procedural memory, the long-term retention and execution of skills learned in earlier life stages, has not yet been systematically investigated in Parkinson’s disease.
Objective: This study aims to investigate the retrograde procedural memory in people with Parkinson’s disease. We hypothesized that the retrograde procedural memory is impaired in people with Parkinson’s disease compared to an age- and gender-matched control group.
Methods: First, we developed an extended evaluation system based on the Cube Copying Test to distinguish the cube copying procedure, representing functioning of the retrograde procedural memory, and the final result, representing the visuo-constructive abilities. Development of the evaluation system included tests of discriminant validity.
Results: Comparing people with typical Parkinson’s disease (n=201) with age- and gender-matched control subjects (n=201), we identified cube copying performance to be significantly impaired in people with Parkinson’s disease (p=0.008). No significant correlation was observed between retrograde procedural memory and disease duration.
Conclusions: We demonstrated lower cube copying performance in people with Parkinson’s disease compared to control subjects, which suggests an impaired functioning of the retrograde procedural memory in Parkinson’s disease.
title: Meta-analysis of gender-dependent gene expression alterations in Parkinson’s disease
Creators: name: Tranchevent, Léon-Charles
name: HALDER, Rashi
name: Glaab, Enrico
Publisher: name: LCSB
Year: 2021

description: Parkinson’s disease (PD) is one of the most common neurological movement disorders. In the incidence and the clinical features of PD, significant gender differences have been observed. While males have a higher disease prevalence and are more frequently affected by muscle rigidity, females present more often with disabling tremors. The molecular mechanisms behind these disease-associated gender differences are still largely unknown, and an improved understanding of the factors involved may open new avenues for pharmacological disease modification. To help address this challenge, we have conducted a meta-analysis of disease-associated molecular gender differences in brain transcriptomics data from PD case/control studies. We studied gender-dependent expression changes in individual genes and using systems level pathway and network analyses to identify coordinated gender-related molecular alterations. In each analysis, both gender-specific changes (significant alteration in only one gender) and gender-dimorphic changes (changes in both genders, but with opposite direction) were identified. These analyses revealed significant disease-associated sex differences in immune response processes and mitochondrial pathways, and highlight specific regulatory factors, such as the transcription factor NR4A2, whose activity changes can explain downstream network alterations, propagated through gene regulatory cascades. Single-cell expression data analyses confirmed many of the pathway-level changes observed in bulk transcriptomics data, and highlighted oligodendrocytes and astrocytes as key affected cell types. Overall, our analyses revealed significant gender disparities in PD-associated transcriptomic changes, resulting in coordinated modulations of molecular processes. Among the regulatory factors involved, NR4A2 has previously been reported to harbour rare mutations in familial PD, and its pharmacological activation conferred neuroprotective effects in toxin-induced models of Parkinsonism. NR4A2 may therefore warrant further preclinical research as a potential drug target for the adjuvant treatment of gender-related pathological features of PD.
Quantum cosmology of (loop) quantum gravity condensates: An example
Creators: name: Gielen, Steffen
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Spatially homogeneous universes can be described in (loop) quantum gravity as condensates of elementary excitations of space. Their treatment is easiest in the second-quantised group field theory formalism which allows the adaptation of techniques from the description of Bose-Einstein condensates in condensed matter physics. Dynamical equations for the states can be derived directly from the underlying quantum gravity dynamics. The analogue of the Gross-Pitaevskii equation defines an anisotropic quantum cosmology model, in which the condensate wavefunction becomes a quantum cosmology wavefunction on minisuperspace. To illustrate this general formalism, we give a mapping of the gauge-invariant geometric data for a tetrahedron to a minisuperspace of homogeneous anisotropic 3-metrics. We then study an example for which we give the resulting quantum cosmology model in the general anisotropic case and derive the general analytical solution for isotropic universes. We discuss the interpretation of these solutions. We suggest that the WKB approximation used in previous studies, corresponding to semiclassical fundamental degrees of freedom of quantum geometry, should be replaced by a notion of semiclassicality that refers to large-scale observables instead.
description: 22 pages, IOP style; v2: revised discussion of explicit solutions in section 4, minor changes in the rest, main conclusions are unchanged; v3: expanded discussion, minor changes to match published version
title: Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-G2019S - associated gene expression
Creators: name: Zagare, Alise
name: Barmpa, Kyriaki
name: Smajic, Semra
name: Smits, Lisa
name: Grzyb, Kamil
name: Grünewald, Anne
name: Skupin, Alexander
name: Nickels, Sarah Louise
name: Schwamborn, Jens Christian
Publisher: name: Cell Press
Year: 2021

description: Human brain organoid models that recapitulate the physiology and complexity of the human brain have a great potential for in vitro disease modeling, in particular for neurodegenerative diseases, such as Parkinson’s disease. In the present study, we compare single-cell RNA sequencing data of human midbrain organoids to the developing human embryonic midbrain. We demonstrate that the in vitro model is comparable to its in vivo equivalents in terms of developmental path and cellular composition. Moreover, we investigate the potential of midbrain organoids for modeling early developmental changes in Parkinson’s disease. Therefore, we compare the single cell-RNA sequencing data of healthy individual-derived midbrain organoids to their isogenic LRRK2-G2019S inserted/mutated counterparts. We show that the LRRK2-G2019S mutation alters neurodevelopment, resulting in an untimely and incomplete differentiation with reduced cellular variability. Finally, we present four candidate genes APP, DNAJC6, GATA3 and PTN that might contribute to the LRRK2-G2019S associated transcriptome changes during early neurodevelopment.
Additional file 1 of Barriers and facilitators to physical activity in people with an inflammatory joint disease: a mixed methods study
Creators: name: Bell, Kirsty
name: Conde, Monserrat
name: Hendry, Gordon
name: Rafferty, Danny
name: Steultjens, Martijn
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1.
X-ray Observations of XSS J12270-4859 in a New Low State: A Transformation to a Disk-Free Rotation-Powered Pulsar Binary
Creators: name: Bogdanov, Slavko
name: Patruno, Alessandro
name: Archibald, Anne M.
name: Bassa, Cees
name: Hessels, Jason W. T.
name: Janssen, Gemma H.
name: Stappers, Ben W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present XMM-Newton and Chandra observations of the low-mass X-ray binary XSS J12270--4859, which experienced a dramatic decline in optical/X-ray brightness at the end of 2012, indicative of the disappearance of its accretion disk. In this new state, the system exhibits previously absent orbital-phase-dependent, large-amplitude X-ray modulations with a decline in flux at superior conjunction. The X-ray emission remains predominantly non-thermal but with an order of magnitude lower mean luminosity and significantly harder spectrum relative to the previous high flux state. This phenomenology is identical to the behavior of the radio millisecond pulsar binary PSR J1023+0038 in the absence of an accretion disk, where the X-ray emission is produced in an intra-binary shock driven by the pulsar wind. This further demonstrates that XSS J12270-4859 no longer has an accretion disk and has transformed to a full-fledged eclipsing "redback" system that hosts an active rotation-powered millisecond pulsar. There is no evidence for diffuse X-ray emission associated with the binary that may arise due to outflows or a wind nebula. An extended source situated 1.5' from XSS J12270--4859 is unlikely to be associated, and is probably a previously uncatalogued galaxy cluster.
description: 8 pages, 6 figures; accepted for publication in the Astrophysical Journal
title: Single cell transcriptomics of human iPSC differentiation dynamics reveal a core network of Parkinson’s disease
Creators: name: Novak, Gabriela
name: KYRIAKIS, DIMITRIOS
name: Bernini, Michela
name: Dittmar, Gunnar
name: Finkbeiner, Steven
name: SKUPIN, Alexander
Publisher: name: LCSB
Year: 2021

description: Parkinson’s disease (PD) is the second-most prevalent neurodegenerative disorder, characterized by the loss of dopaminergic neurons (mDA) in the midbrain. The underlying mechanisms are only partly understood and there is no treatment to reverse PD progression. Here, we investigated the disease mechanism using mDA neurons differentiated from human induced pluripotent stem cells (hiPSCs) carrying the ILE368ASN mutation within the PINK1 gene, which is strongly associated with PD. Single-cell RNA sequencing (RNAseq) and gene expression analysis of a PINK1 and a control cell line identified genes differentially expressed during mDA neuron differentiation. Network analysis revealed that these genes form a core network, members of which interact with all known 19 protein-coding Parkinson’s disease-associated genes. This core network encompasses key PD-associated pathways, including ubiquitination, mitochondrial function, protein processing, RNA metabolism, and vesicular transport. Proteomics analysis showed a consistent alteration in proteins of dopamine metabolism, indicating a defect of dopaminergic metabolism in PINK1 neurons. Our findings suggest the existence of a network onto which pathways associated with PD pathology converge, and offers new interpretation of the phenotypic heterogeneity ofPD.
Cosmological parameter fittings with the BICEP2 data
Creators: name: Wu, Fengquan
name: Li, Yichao
name: Lu, Youjun
name: Chen, Xuelei
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Combining the latest Planck, Wilkinson Microwave Anisotropy Probe (WMAP), and baryon acoustic oscillation (BAO) data, we exploit the recent cosmic microwave background (CMB) B-mode power spectra data released by the BICEP2 collaboration to constrain the cosmological parameters of the $Λ$CDM model, esp. the primordial power spectra parameters of the scalar and the tensor modes, $n_s,α_s, r, n_t$. We obtained constraints on the parameters for a lensed $Λ$CDM model using the Markov Chain Monte Carlo (MCMC) technique, the marginalized $68\%$ bounds are $r = 0.1043\pm_{0.0914}^{0.0307}$, $n_s = 0.9617\pm_{0.0061}^{ 0.0061}$, $α_s = -0.0175\pm_{0.0097}^{0.0105}$, $n_t = 0.5198\pm_{0.4579}^{0.4515}$. We found that a blue tilt for $n_t$ is favored slightly, but it is still well consistent with flat or even red tilt. Our $r$ value is slightly smaller than the one obtained by the BICEP team, as we allow $n_t$ as a free parameter without imposing the single-field slow roll inflation consistency relation. If we impose this relation, $r=0.2130\pm_{0.0609}^{0.0446}$. For most other parameters, the best fit values and measurement errors are not altered much by the introduction of the BICEP2 data.
РОЛЬ И ЗНАЧЕНИЕ АДМИНИСТРАТИВНОЙ ОТВЕТСТВЕННОСТИ В СИСТЕМЕ МЕР ОТВЕТСТВЕННОСТИ ЗА НАРУШЕНИЕ РЕКЛАМНОГО ЗАКОНОДАТЕЛЬСТВА
Creators: name: ГАБДРАХМАНОВА Р.А.
name: ГУМЕРОВА Л.Ш.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: РЕКЛАМА
РЕКЛАМНОЕ ЗАКОНОДАТЕЛЬСТВО
ЮРИДИЧЕСКАЯ ОТВЕТСТВЕННОСТЬ
АДМИНИСТРАТИВНАЯ ОТВЕТСТВЕННОСТЬ
ГРАЖДАНСКАЯ ОТВЕТСТВЕННОСТЬ
ADVERTISING
ADVERTISING LEGISLATION
LEGAL RESPONSIBILITY
ADMINISTRATIVE RESPONSIBILITY
CIVIL RESPONSIBILITY

description: В данной статье рассматриваются такие понятия, как «административная ответственность», «гражданская ответственность» за нарушение законодательства о рекламе, даны их определения и разобраны проблемы правоприменения. В работе изучена роль и значение административной ответственности в системе мер ответственности за нарушение российского рекламного законодательства. Автором анализируются нормативно-правовые акты, приводятся позиции ученых-правоведов и практикующих юристов.
МЕСТО МЕЖДУНАРОДНОГО ЧАСТНОГО ПРАВА В ПРАВОВОЙ СИСТЕМЕ РОССИЙСКОЙ ФЕДЕРАЦИИ
Creators: name: ГУСАРОВА Е.А.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: МЕЖДУНАРОДНОЕ ЧАСТНОЕ ПРАВО
ИНОСТРАННЫЕ ЭЛЕМЕНТЫ
ГОСУДАРСТВО
ПУБЛИЧНОЕ ПРАВО
ОТРАСЛЬ ПРАВА
PRIVATE INTERNATIONAL LAW
FOREIGN ELEMENTS
STATE
PUBLIC LAW
BRANCH OF LAW

description: В статье исследуется вопрос определения подхода к понимаю понятия и места международного частного права в системе права Российской Федерации. Рассматриваются различные точки зрения, относительно формирования данной отрасли права и ее содержания. Актуальность указанного вопроса состоит в обширном применении отрасли международного частного права и взаимодействии ее с иными правовыми категориями российского права. Главная проблема, которая все ещё не была решена учеными, состоит в выделении международного частного права в отдельную отрасль национального права, что впоследствии приведёт к совершенствованию российского законодательства и формированию наиболее обширного механизма правового регулирования.
Additional file 1 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma
Creators: name: Imamura, Taisuke
name: Okamura, Yukiyasu
name: Ohshima, Keiichi
name: Uesaka, Katsuhiko
name: Sugiura, Teiichi
name: Ito, Takaaki
name: Yamamoto, Yusuke
name: Ashida, Ryo
name: Ohgi, Katsuhisa
name: Otsuka, Shimpei
name: Ohnami, Sumiko
name: Nagashima, Takeshi
name: Hatakeyama, Keiichi
name: Sugino, Takashi
name: Urakami, Kenichi
name: Akiyama, Yasuto
name: Yamaguchi, Ken
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cancer

description: Additional file 1: Supplementary Fig. 1. Mutation signature in the sample with multiple mutations. Supplementary Fig. 2. The distribution of TMB in HCCs. Supplementary Fig. 3. The mutational mapping of MMs in CTNNB1 and MUC16. Supplementary Fig. 4. Drug sensitivity screens in Cancer Cell Line Encyclopedia.
Abelian Duality at Higher Genus
Creators: name: Beasley, Chris
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In three dimensions, a free, periodic scalar field is related by duality to an abelian gauge field. Here I explore aspects of this duality when both theories are quantized on a Riemann surface of genus g. At higher genus, duality involves an identification of winding with momentum on the Jacobian variety of the Riemann surface. I also consider duality for monopole and loop operators on the surface and exhibit the operator algebra, a refinement of the Wilson-'t Hooft algebra.
description: 53 pages, 1 figure, v2: references added
Additional file 2 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma
Creators: name: Imamura, Taisuke
name: Okamura, Yukiyasu
name: Ohshima, Keiichi
name: Uesaka, Katsuhiko
name: Sugiura, Teiichi
name: Ito, Takaaki
name: Yamamoto, Yusuke
name: Ashida, Ryo
name: Ohgi, Katsuhisa
name: Otsuka, Shimpei
name: Ohnami, Sumiko
name: Nagashima, Takeshi
name: Hatakeyama, Keiichi
name: Sugino, Takashi
name: Urakami, Kenichi
name: Akiyama, Yasuto
name: Yamaguchi, Ken
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cancer

description: Additional file 2: Supplementary Table 1. Mutations identified in MUC16.
title: The Parkinson’s disease associated mutation LRRK2-G2019S alters 2 dopaminergic differentiation dynamics via NR2F1
Creators: name: Walter, Jonas
name: Bolognin, Silvia
name: K. Poovathingal, Suresh
name: Magni, Stefano
name: Krüger, Rejko
name: Sauter, Thomas
name: Studer, Michéle
name: Pereira de Almeida, Luis
name: J. Tronstad, Karl
name: Sinkkonen, Lasse
name: Skupin, Alexander
name: Schwamborn, Jens C.
Publisher: name: LCSB
Year: 2021

description:
Increasing evidence suggests that neurodevelopmental alterations might contribute to increase the susceptibility to develop neurodegenerative diseases later in life. We investigated the occurrence of developmental abnormalities in dopaminergic neurons in a model of Parkinson’s disease (PD). We monitored over time the differentiation of human patient-specific neuroepithelial stem cells (NESCs) into dopaminergic neurons. Using high-throughput image analyses and single-cell RNA-sequencing, we observed that the PD-associated LRRK2-G2019S mutation alters the initial phase of neuronal differentiation by accelerating cell cycle exit with a concomitant increase in cell death. We identified the NESC-specific core regulatory circuit and a molecular mechanism underlying the observed phenotypes. The expression of NR2F1, a key transcription factor involved in neurogenesis, decreased in LRRK2-G2019S NESCs, neurons, and midbrain organoids compared to controls. We also observed accelerated dopaminergic differentiation in vivo in NR2F1 deficient mouse embryos. This suggests a novel pathogenic mechanism involving the LRRK2-G2019S mutation, where the dynamics of dopaminergic differentiation are modified via NR2F1.
СУЩНОСТЬ ДОГОВОРА ФИНАНСИРОВАНИЯ ПОД УСТУПКУ ДЕНЕЖНОГО ТРЕБОВАНИЯ
Creators: name: ДОСУМБЕТОВ Д.К.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: ДОГОВОР ФИНАНСИРОВАНИЯ ПОД УСТУПКУ ДЕНЕЖНОГО ТРЕБОВАНИЯ
ФАКТОРИНГ
РЕАЛЬНЫЙ И КОНСЕНСУАЛЬНЫЙ ХАРАКТЕР ДОГОВОРА
КОММУТАТИВНЫЙ И АЛЕАТОРНЫЙ ДОГОВОРЫ
FINANCING AGREEMENT AGAINST THE ASSIGNMENT OF A MONETARY CLAIM
FACTORING
THE REAL AND CONSENSUAL NATURE OF THE TREATY
COMMUTATIVE AND ALEATORY CONTRACTS

description: В статье исследуется правовая природа договора финансирования под уступку денежного требования. На основе анализа доктринальных положений и норм Гражданского кодекса КР автором выявляются сущностные черты рассматриваемого договора. В частности, определяется целевая направленность договора, позволяющая относить его к группе договоров о передаче имущества в собственность, отстаивается позиция о коммутативности договора.
title: Method optimization of skin biopsy-derived fibroblast culture for reprogramming into induced pluripotent stem cells (iPSCs)
Creators: name: Mommaerts, Kathleen
name: Bellora, Camille
name: Lambert, Pauline
name: Türkmen, Seval
name: Schwamborn, Jens C.
name: Betsou, Fay
Publisher: name: LCSB
Year: 2021

description: Fibroblasts can be isolated from skin biopsies using either a chemical dissociation, a physical dissociation or a combination of both techniques. They can be reprogrammed into induced pluripotent stem cells (iPSCs) through the introduction of defined sets of key transcription factors. This study aimed to identify the optimal protocol for skin biopsy dissociation, fibroblast culture and fibroblast cryopreservation in the scope of reprogramming into iPSCs and in the context of biobank accreditation
Entanglement tongue and quantum synchronization of disordered oscillators
Creators: name: Lee, Tony E.
name: Chan, Ching-Kit
name: Wang, Shenshen
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We study the synchronization of dissipatively-coupled van der Pol oscillators in the quantum limit, when each oscillator is near its quantum ground state. Two quantum oscillators with different frequencies exhibit an entanglement tongue, which is the quantum analogue of an Arnold tongue. It means that the oscillators are entangled in steady state when the coupling strength is greater than a critical value, and the critical coupling increases with detuning. An ensemble of many oscillators with random frequencies still exhibits a synchronization phase transition in the quantum limit, and we analytically calculate how the critical coupling depends on the frequency disorder. Our results can be experimentally observed with trapped ions or neutral atoms.
description: 11 pages, 5 figures
[Foreword]
Creators: name: Aßmus, Marcus
name: Eremeyev, Victor A.
name: Öchsner, Andreas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2021
Subjects: subject: Holm Altenbach
subject: Birthday
subject: Continuum and structural mechanics
subject: 621.8

description: The particular occasion that motivated the organization of this special issue was the upcoming date for the 65th birthday of Professor Holm Altenbach.
ИСТОРИЯ СТАНОВЛЕНИЯ И РАЗВИТИЯ АРБИТРАЖНЫХ СУДОВ В РФ
Creators: name: ДЫДЫГИНА Ю.Н.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: СУД
АРБИТРАЖНЫЙ ПРОЦЕСС
ЭКОНОМИЧЕСКИЙ СПОР
РЕШЕНИЕ СУДА
КОММЕРЧЕСКИЙ СУД
COURT
ARBITRATION
BUSINESS DISPUTE
THE DECISION OF THE COURT
COMMERCIAL COURT

description: В статье рассмотрены исторические аспекты становления российской системы арбитражных судов, их совершенствования и развития, современное состояние. Приведена история появления первых арбитражных судов в России во времена Древней Руси, их реформирование во времена российской империи, революции, а также после принятия Арбитражного процессуального кодекса. Автор проводит сравнение арбитражного судопроизводства в Российской Федерации и зарубежных странах, таких как США и Англия и делает вывод о невозможности принятия в РФ той системы арбитражных судов, которая действует в указанных европейских государствах.
ВЛИЯНИЕ ЦИФРОВЫХ ТЕХНОЛОГИЙ НА КРИМИНАЛИСТИЧЕСКОЕ ИССЛЕДОВАНИЕ ПОДПИСИ
Creators: name: ЕГОРОВА Е.П.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: КРИМИНАЛИСТИЧЕСКОЕ ИССЛЕДОВАНИЕ ДОКУМЕНТОВ
ЦИФРОВЫЕ ТЕХНОЛОГИИ
КРИМИНАЛИСТИКА
ЦИФРОВОЕ ИЗОБРАЖЕНИЕ
ЭКСПЕРТ-ПОЧЕРКОВЕД
ПОДПИСИ
FORENSIC HANDWRITING EXPERTISE
DIGITAL TECHNOLOGIES
CRIMINALISTICS
DIGITAL IMAGE
HANDWRITING EXPERT
SIGNATURES

description: Автором данной научной статьи поднимается вопрос о том, как на сегодняшний день цифровые технологии способствуют развитию новых способов фальсификации документов на высоком технологическом уровне. Это приводит к внедрению и широкому применению их в преступной деятельности. Чтобы установить определенные факты и способы фальсификации письменных документов, проводится криминалистическое исследование документов и его реквизитов.
Additional file 3 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma
Creators: name: Imamura, Taisuke
name: Okamura, Yukiyasu
name: Ohshima, Keiichi
name: Uesaka, Katsuhiko
name: Sugiura, Teiichi
name: Ito, Takaaki
name: Yamamoto, Yusuke
name: Ashida, Ryo
name: Ohgi, Katsuhisa
name: Otsuka, Shimpei
name: Ohnami, Sumiko
name: Nagashima, Takeshi
name: Hatakeyama, Keiichi
name: Sugino, Takashi
name: Urakami, Kenichi
name: Akiyama, Yasuto
name: Yamaguchi, Ken
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cancer

description: Additional file 3: Supplementary Table 2. Gene expression raw data.
title: A "two-hit" pharmacological seizure model in zebrafish for studying microglia dynamics in the developing epileptic brain
Creators: name: Martins, Teresa
name: Soliman, Remon
name: Donato, Cristina
name: Cordero-Maldonado, Maria Lorena
name: Ameli, Corrado
name: Mombaerts, Laurent
name: SKUPIN, Alexander
name: Peri, Francesca
name: Crawford, Alexander D.
Publisher: name: LCSB
Year: 2021

description: Epilepsy is a chronic brain disorder characterized by unprovoked and recurrent seizures, of which 60% are of unknown etiology. Recent studies implicate microglia in the pathophysiology of epilepsy. However, their role in this process, e.g. following early-life seizures, remains poorly understood in part due to the lack of suitable experimental models allowing the in vivo imaging of microglial activity using minimally-invasive techniques. Given the advantage of zebrafish larvae for such imaging approaches, we sought to develop a "two-hit" pharmacological seizure model in zebrafish suitable for studying microglia response after acute seizures. Towards this end, different concentrations of kainate were microinjected intravenously into 3 days post-fertilization transgenic zebrafish larvae with mCherry-labeled microglia followed by acute incubation with pentylenetetrazole at 5 days post-fertilization. Kainate-treated larvae exhibited increased numbers of microglia in the brain, and were more susceptible to subsequent pentylenetetrazole-induced seizures, as shown by higher locomotor and encephalographic activity as compared to vehicle-injected larvae. These results are comparable to experimental kainate-induced rodent seizure models and suggest the suitability of our model for future studies. Such studies could contribute to elucidate microglial dynamic changes after seizure induction in the developing brain, and to understand how these modulate seizure susceptibility later in life.
ВОПРОСЫ КВАЛИФИКАЦИИ ХИЩЕНИЙ ЭЛЕКТРОННЫХ ДЕНЕЖНЫХ СРЕДСТВ
Creators: name: ЕГОРОВА Е.П.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: ХИЩЕНИЕ
ЭЛЕКТРОННОЕ ДЕНЕЖНОЕ СРЕДСТВО
НАЦИОНАЛЬНАЯ ПЛАТЕЖНАЯ СИСТЕМА
БАНКОВСКИЙ СЧЕТ
СРЕДСТВО ПЛАТЕЖА
УЧЕТНЫЕ ДАННЫЕ СОБСТВЕННИКА
THEFT
ELECTRONIC MONEY
NATIONAL PAYMENT SYSTEM
BANK ACCOUNT
MEANS OF PAYMENT
OWNER'S CREDENTIALS

description: В статье обращено внимание на отдельные вопросы учитываемые при квалификации хищений электронных денежных средств и средств граждан, находящихся на банковских счетах. Осуществлен анализ правоприменительной практики, по результату которого акцентировано внимание на том, что правоприменители ряда регионов Российской Федерации имеют именно проблемы, связанные с вопросами правильной квалификации рассматриваемой в статье категории хищений. Рассмотрены ключевые решения судов имеющие примеры правильной и ошибочной квалификации. Высказано мнение, указывающее на потребность в переработке ряда решений Верховного Суда Российской Федерации, особенно тех, которые дают рекомендации о применении положений закона в отношении преступных проявлений соприкасающихся или совершенных с использованием информационно-коммуникационных технологий или в сфере высоких технологий.
In-plane Chiral Tunneling and Out-of-plane Valley-polarized Quantum Tunneling in Twisted Graphene Trilayer
Creators: name: Qiao, Jia-Bin
name: He, Lin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Here we show that twisted graphene trilayer made by misoriented stacking a graphene monolayer on top of a Bernal graphene bilayer can exhibit rich and tailored electronic properties. For the case that the graphene monolayer and bilayer are strongly coupled, both the massless Dirac fermions and massive chiral fermions coexist in the twisted trilayer, leading to unique in-plane chiral tunneling. For a weak coupling between the two graphene systems, the distinct chiralities and pseudospin textures of quasiparticles in monolayer and bilayer enable vertical valley-polarized quantum tunneling between them. Intriguingly, the polarity of the valley polarization can be inverted by controlling the rotational angles between the two systems. Our results indicate that layered van der Waals structures assembled from individual atomic planes can create materials that harbor unusual properties and new functionalities depending on how the crystalline layers are stacked.
description: 4 figures. To appear in PRB
СТАНОВЛЕНИЕ НОРМ ПРЕДПРИНИМАТЕЛЬСКОГО ПРАВА В КЫРГЫЗСКОЙ РЕСПУБЛИКЕ
Creators: name: ЖАПАРКУЛОВА Н.Ж.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: ПРАВО
ПРЕДПРИНИМАТЕЛЬСКОЕ ПРАВО
ГОСУДАРСТВЕННЫЕ ОРГАНЫ
ПРАВОВЫЕ НОРМЫ ЮРИДИЧЕСКАЯ ЗАЩИТА
LAW
BUSINESS LAW
GOVERNMENT BODIES
LEGAL NORMS
LEGAL PROTECTION

description: Практика формирования рыночной экономики в Кыргызстане осуществляется в рамках предпринимательского права с применением в необходимых случаях элементов публичного права. В статье рассматривается проблематика предпринимательского права Кыргызской Республике, которая далеко выходит за рамки гражданско-правового регулирования. Это относится не только к предмету и методам данной отрасли права, но и к ее субъектам, к правовым формам государственного регулирования хозяйственной деятельности и ко многим другим вопросам. В процессе осуществления различных видов деятельности складываются общественные отношения, регулируемые различными отраслями права.
Context dependency of time-based event-related expectations for different modalities
Creators: name: Ball, Felix
name: Andreca, Julia
name: Noesselt, Tömme
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: Modalities
subject: Time-based event-related expectations (TBEEs)
subject: 150.72

description: Expectations about the temporal occurrence of events (when) are often tied with the expectations about certain event-related properties (what and where) happening at these time points. For instance, slowly waking up in the morning we expect our alarm clock to go off; however, the longer we do not hear it the more likely we already missed it. However, most current evidence for complex time-based event-related expectations (TBEEs) is based on the visual modality. Here we tested whether implicit TBEEs can act cross-modally. To this end, visual and auditory stimulus streams were presented which contained early and late targets embedded among distractors (to maximise temporal target uncertainty). Foreperiod-modality-contingencies were manipulated run-wise: visual targets either occurred early in 80% of trials and auditory targets occurred late in 80% of trials or vice versa. Participants showed increased sensitivity for expected auditory early/visual late targets which increased over time while the opposite pattern was observed for visual early/auditory late targets. A benefit in reaction times was only found for auditory early trials. Together, this pattern of results suggests that implicit context-dependent TBEEs for auditory targets after short foreperiods (be they correct or not) dominated and determined which modality became more expected at the late position irrespective of the veridical statistical regularity. Hence, TBEEs in cross-modal and uncertain environments are context-dependent, shaped by the dominant modality in temporal tasks (i.e., auditory) and only boost performance cross-modally when expectations about the event after the short foreperiod match with the run-wise context (i.e., auditory early/visual late).
ГОСУДАРСТВЕННОЕ И ПРАВОВОЕ РЕГУЛИРОВАНИЕ РЫНКА МЕДИЦИНСКИХ УСЛУГ В РОССИИ
Creators: name: ЗАХАРОВА А.В.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: ГОСУДАРСТВО
ЗАКОН
ЗДРАВООХРАНЕНИЕ
МЕДИЦИНСКИЕ УСЛУГИ
ГОСУДАРСТВЕННОЕ РЕГУЛИРОВАНИЕ
ПРАВОВОЕ РЕГУЛИРОВАНИЕ МЕДИЦИНСКИХ УСЛУГ
STATE
LAW
HEALTH CARE
MEDICAL SERVICES
STATE REGULATION
LEGAL REGULATION OF MEDICAL SERVICES

description: В данной статье рассматриваются вопросы государственного и правового регулирования рынка медицинских услуг, рассматриваются основные нормативные документы, регулирующие данный рынок. У всех граждан есть право на получение бесплатной медицинской помощи в различных системах здравоохранения: государственных и муниципальных. Гарантированный объем медицинской помощи предоставляется гражданам в соответствии с государственными гарантийными программами по предоставлению бесплатной медицинской помощи гражданам России. Рассмотрены методы регулирования рынка медицинских услуг, озвучены права граждан на медицинскую и социальную помощь.
title: Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR
Creators: name: Scherer, Michael
name: Gasparoni, Gilles
name: Rahmouni, Souad
name: Shashkova, Tatiana
name: Arnoux, Marion
name: Louis, Edouard
name: Nostaeva, Arina
name: Avalos, Diana
name: Dermitzakis, Emmanouil T.
name: Aulchenko, Yurii S.
name: Lengauer, Thomas
name: Lyons, Paul A.
name: Georges, Michel
name: Walter, Jörn
Publisher: name: LCSB
Year: 2021

description: Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease. The dataset developed in this project provides matched genotyping and DNA methylation data in four tissues (ileum, rectum, T-cells, B-cells) from healthy individuals. Using this data, we demonstrate the discrimination of common from cell-type-specific methQTLs. Our analysis demonstrates that a systematic analysis of methQTLs provides important new insights on the influences of genetic variants to cell-type-specific epigenomic variation.
Dragging of inertial frames inside the rotating neutron stars
Creators: name: Chakraborty, Chandrachur
name: Modak, Kamakshya Prasad
name: Bandyopadhyay, Debades
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We derive the exact frame-dragging rate inside rotating neutron stars. This formula is applied to show that the frame-dragging rate monotonically decreases from the centre to the surface of the neutron star along the pole. In case of frame-dragging rate along the equatorial distance, it decreases initially away from the centre, becomes negligibly small well before the surface of the neutron star, rises again and finally approaches to a small value at the surface. The appearance of local maximum and minimum in this case is the result of the dependence of frame-dragging frequency on the distance and angle. Moving from the equator to the pole, it is observed that this local maximum and minimum in the frame dragging rate along the equator disappears after crossing a critical angle. It is also noted that the positions of local maximum and minimum of the frame-dragging rate along the equator depend on the rotation frequency and central energy density of a particular pulsar.
description: LaTex; 12 pages including 16 figures, version accepted for publication in ApJ
Early Byzantine terracotta oil lamp
Creators: name: Museum, Centre for Ancient Cultures
Publisher: name: Monash University
Year: 2022
Subjects: Other history, heritage and archaeology not elsewhere classified
Archaeology not elsewhere classified
Archaeology of Europe, the Mediterranean and the Levant
Archaeology of Asia, Africa and the Americas
Ceramics
Heritage, archive and museum studies not elsewhere classified
Classical Greek and Roman history

description: Syrian mold-made ceramic vessel with almond-shaped body and pointed short handle and curved sides. In the centre of the discus, a wide filling-hole and double raised rim. A band of vegetal decoration (laurel wreath) appears on the shoulders. Single base ring, raised in circle, slightly concave base. It displays a cross in relief just above the nozzle. This symbol served as an invocation, or appeal, for the divine protection. On lamps of this type the large circular discus typical of earlier Roman lamps (see Object number 127.061) that had served as a kind of “canvas” for decorative images is gone. The decoration here is focused on the shoulders of the lamp. Oil lamps were used in ancient times to light homes at night. They were fueled by fish oil, animal oil and fat but mainly by vegetable (olive) oil. A woven fibrous wick was placed in the hole at the tip of the lamp to burn the oil. Object number: 127.064 Date: 5th century A.D. Parallels: New York, Metropolitan Museum of Art 28.99.16; Detroit, Detroit Institute of Arts 24.128.AA, 24.128.CC, 72.398, 72.400; Baltimore, The Walters Art Museum 48.2569; London, British Museum 1868,0620.198.1, OA.300, OA.4337, compare with 1857,1218.181, 1868,0620.198.1, 1974,0424.6, 1987,0603.1; Milwaukee, Milwaukee Public Museum A15856/5253, N33029/27091, N3059/NA, N11554/32365. References: Dean, Bashford. "A Crusaders' Fortress in Palestine: a Report of Explorations Made by the Museum, 1926." The Metropolitan Museum of Art Bulletin, pp. 26, 34, fig. 49; Broneer, O., Corinth IV vol. 2: Terracotta lamps. Princeton, N.J., American School of Classical Studies at Athens, 1930; Bailey, D., A Catalogue of the Lamps in the British Museum. III. Roman Provincial Lamps, London, 1988, no. Q1869, 210, pl. 31, 147 with comparanda; The Metropolitan Museum of Art, Andrea Bayer, Laura D. Corey, Morrison H. Heckscher, Katharine Baetjer, Joan R. Mertens, and Barbara Drake Boehm. Making the Met, 1870–2020, New York: The Metropolitan Museum of Art, 2020. pp. 104, 249, fig. 107
 Photo by Steve Morton
Renormalization group study of interaction-driven quantum anomalous Hall and quantum spin Hall phases in quadratic band crossing systems
Creators: name: Murray, James M.
name: Vafek, Oskar
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: It is shown that topological insulating phases driven by interactions can be realized without the need for spin-orbit coupling or large intersite interaction in a two-dimensional system of spin-1/2 fermions with a single pair of parabolically touching bands. Using a weak-coupling, Wilsonian renormalization group procedure, we show that a quantum anomalous Hall phase is realized for Hubbard interaction, while a quantum spin Hall phase is favored for longer-ranged interactions.
description: 4+3 pages. Published version
ИНСТИТУТ ПРЕДСТАВИТЕЛЬСТВА В ГРАЖДАНСКОМ ПРОЦЕССЕ КАК СРЕДСТВО ГАРАНТИРОВАНИЯ КОНСТИТУЦИОННЫХ ОСНОВ СУДОПРОИЗВОДСТВА
Creators: name: НИКОЛЕНКО А.А.
name: ЗОРЬКИНА А.Ю.
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2020
Subjects: ПРЕДСТАВИТЕЛЬСТВО
ГРАЖДАНСКИЙ ПРОЦЕСС
ПРЕДСТАВИТЕЛЬ
СУДЕБНАЯ ЗАЩИТА
КВАЛИФИЦИРОВАННАЯ ЮРИДИЧЕСКАЯ ПОМОЩЬ
REPRESENTATION
CIVIL PROCEDURE
REPRESENTATIVE
JUDICIAL PROTECTION
QUALIFIED LEGAL ASSISTANCE

description: Статья посвящена раскрытию правовой сущности института представительства в гражданском процессе как правового средства, позволяющего лицу участвовать одновременно в нескольких правоотношениях при отсутствии у него таковой физической возможности. Предпринята попытка охарактеризовать внешнюю и внутреннюю стороны судебного представительства как системы процессуальных правоотношений между представляемым, представителем, судом и иными лицами, участвующими в гражданском судопроизводстве.
VICTORIA : VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms
Creators: name: Berg, Philipp
name: Behrendt, Benjamin
name: Voß, Samuel
name: Beuing, Oliver
name: Neyazi, Belal
name: Sandalcioglu, I. Erol
name: Preim, Bernhard
name: Saalfeld, Sylvia
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2021
Subjects: subject: Intracranial aneurysm
subject: Neck curve
subject: Rupture risk assessment
subject: Hemodynamics
subject: VICTORIA
subject: 000

description: Purpose—For the status evaluation of intracranial aneurysms (IAs), morphological and hemodynamic parameters can provide valuable information. For their extraction, a separation of the aneurysm sac from its parent vessel is required that yields the neck curve and the ostium. However, manual and subjective neck curve and ostium definitions might lead to inaccurate IA assessments. Methods—The research project VICTORIA was initiated, allowing users to interactively define the neck curve of five segmented IA models using a web application. The submitted results were qualitatively and quantitatively compared to identify the minimum, median and maximum aneurysm surface area. Finally, image-based blood flow simulations were carried out to assess the effect of variable neck curve definitions on relevant flow- and shear-related parameters. Results—In total, 55 participants (20 physicians) from 18 countries participated in VICTORIA. For relatively simple aneurysms, a good agreement with respect to the neck curve definition was found. However, differences among the participants increased with increasing complexity of the aneurysm. Furthermore, it was observed that the majority of participants excluded any small arteries occurring in the vicinity of an aneurysm. This can lead to non-negligible deviations among the flow- and shear-related parameters, which need to be carefully evaluated, if quantitative analysis is desired. Finally, no differences between participants with medical and non-medical background could be observed. Conclusions—VICTORIAs findings reveal the complexity of aneurysm neck curve definition, especially for bifurcation aneurysms. Standardization appears to be mandatory for future sac-vessel-separations. For hemodynamic simulations a careful neck curve definition is crucial to avoid inaccuracies during the quantitative flow analysis.