cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Investigating the role of transfer RNA regulation during murine gammaherpesvirus 68 infection
Creators: name: Jimenez, Ariana Rose
Publisher: name: University of Iowa
Year: 2025
Subjects: subject: gammaherpesviruses
subject: host-pathogen interactions
subject: tRNA
subject: tRNA fragments (tRFs)
subject: public abstract
subject: Immunology
subject: FOS: Clinical medicine

description: Gammaherpesviruses (gHV) are lymphotropic DNA viruses, undergoing both lytic and latent infection. Kaposi sarcoma-associated herpesvirus (KSHV) is a gHV that causes lifelong infection in immunocompromised hosts, particularly those affected by AIDS. KSHV, like many viruses, alters the host gene expression landscape to increase virulence. Interestingly, transfer RNA (tRNA) synthesis is robustly stimulated by virus infection. There is a critical need to understand how KSHV alters the host gene expression landscape, including tRNA synthesis, to aid in creating novel therapeutics against KSHV. To study lytic infection in vitro, we utilize the functional and genetic homolog, murine gammaherpesvirus 68 (MHV68). Here, we investigate how MHV68 infection impacts tRNA expression. Following MHV68 infection, premature tRNA (pre-tRNA) and tRNA fragment (tRF) expression are upregulated following MHV68 infection, confirmed by using pre-tRNA-Tyr and 5’ tRF-Tyr as model tRNA species. Stem loop reverse transcription quantitative polymerase chain reaction (SL RT- qPCR) was optimized and successfully applied to quantitatively measure tRF expression during MHV68 infection. Further, functional consequences of altered pre-tRNA-Tyr and of 5’ tRF-Tyr expression during MHV68 infection were investigated. We found that tRF upregulation is dependent on post-entry viral gene expression but did not find a direct functional role for 5’ tRF-Tyr. Overall, these findings provide tools for further investigation of tRNA dysregulation that occurs as a result of gHV infections.
D1.1 - Data Management Plan
Creators: name: Thuermer, Gefion
Publisher: name: Zenodo
Year: 2020
Subjects: Data Management
Open Data
Open Science
Quantitative
Qualitative
Licenses

description: This document serves as the data management plan for the ACTION project and consists of individual data management plans for all datasets held across the ACTION consortium, and covering the activities of, both in terms of pilot projects and work package research activities.
Acute Motor Axonal Neuropathy in Association with Hepatitis E
Creators: name: Al-Saffar, Araz
name: Al-Fatly, Bassam
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: Guillain–Barré syndrome
subject: acute motor axonal neuropathy
subject: hepatitis E
subject: muscle weakness
subject: nerve conduction study
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Guillain–Barré syndrome (GBS) is an acute peripheral neuropathy that develops as a result of post-infectious immune-mediated nerve injury. It can be classified into classic and variant GBS. Acute motor axonal neuropathy (AMAN) is a subtype of GBS with the key clinical features of pure motor weakness, areflexia, absence of sensory symptoms, and lack of neurophysiologic evidence of demyelination. We reported a case of acute motor axonal neuropathy in association with hepatitis E infection. A young woman was referred to us after a period of nausea, fever, and diarrhea. She had unexplained muscle weakness at admission and has been diagnosed with acute hepatitis E infection. A rigorous clinical neurological assessment revealed bilateral symmetrical weakness, which affects the lower limbs more than the upper limbs, with no evidence of sensory involvement. Neurophysiological measurements indicated acute axonal injury without clues to demyelination. A diagnosis of acute motor axonal neuropathy subtype has been made, to which she only received supportive therapy. The symptoms resolved spontaneously and full recovery of motor function was attained after 35 days of weakness onset with complete normalization of neurophysiologic parameters.
Educational Segregation by Gender: A Case Study of Brandeis University
Creators: name: Cano, Camila
Publisher: name: Brandeis University
Year: 2023
Subjects: Gender Segregation
College Major Choice
Occupational Segregation
Higher Education

description: Despite significant progress in educational attainment among women, the gender wage gap in the labor force remains a persistent issue. Research has shown that occupational segregation - the concentration of women in certain fields- is a key factor contributing to this gap. This thesis explores the connection between occupational segregation and the segregation of genders across majors through a case study of Brandeis University. Using a mixed-methods approach, the study considers administrative data on gender by major, survey responses, and interviews with undergraduate students to 1) provide a measure of segregation at Brandeis, 2) identify if and how students’ decisions regarding their field of study change during their time at the university and 3) examine the factors that influence students’ choices, while considering differences across genders. I find that 31.9% of female students in the sample would have to switch majors for the distribution of genders to be the same in each. Moreover, students’ fields of study do not change substantially during their time at Brandeis as most students in the sample declare the same major as their intended major and that only 30.21% pursue an additional major in a different field. Finally, students’ choices of major are strongly influenced by their ability to engage with the class content, peers, and professors, and for female students, the race and gender of these individuals have a significant impact. Overall, these findings suggest that gender segregation by major exists at Brandeis and that stronger interventions are necessary to address it. 
Exploring psychological factors and quality of life in individuals living with gastroparesis and the development of a brief online psychological support program.
Creators: name: Woodhouse, Sally
Publisher: name: Swinburne
Year: 2024

description: This PhD research aimed to improve understanding of the relationships between gastroparesis, psychological factors, and quality of life. The research identifies psychological processes that can influence health outcomes in gastroparesis, includes the first evaluation of the Common Sense Model in a gastroparesis cohort, and documents the development and pilot testing of an online psychological intervention for individuals with gastroparesis. The work highlights the potential value of including mental health assessment and treatment in medical programs for gastroparesis sufferers, and provides preliminary evidence for the feasibility of an online psychological intervention program to help support individuals living with gastroparesis.
PhD by Publication.
Lionel Hampton, Stony Brook Fire Department, August 10, 1963
Creators: name: Stony Brook Community Fund
Publisher: name: Unknown
Year: 1963
Subjects: Stony Brook
Concerts
Concert halls
Amphitheaters
Fire stations
Programs

description: This is a concert program for the Stony Brook Fire Department held at Dogwood Hollow's Amphitheatre on August 10, 1963. This Program highlights Lionel Hampton, American jazz musician and bandleader, known for the rhythmic vitality of his playing and his showmanship as a performer. Best known for his work on the vibraphone, Hampton was also a skilled drummer, pianist, and singer.
Time to Welcome Chaos: The Intersection of the Trickster, Creativity, and the Math Classroom
Creators: name: Vidales, Elisa
Publisher: name: Stanford Digital Repository
Year: 2024
Subjects: College students' writings, education, math and arts education, Common Core,

description: This essay won or received an honorable mention for The Boothe Prize for excellence in first-year writing. The Boothe Prize recognizes and rewards outstanding expository and argumentative writing by undergraduate students in first-year classes that satisfy the WR 1 requirement. In each award-winning essay, student writers demonstrate clarity of argument, excellent integration of research-based evidence, and compelling prose style.
This essay uses the “trickster” figure--a mythological, boundary-crossing character that appears in many cultures—to offer a compelling and fresh approach to longstanding deficiencies in our educational system. It proposes the “mathematical trickster” to argue for creativity in the math classroom as a holistic perspective shift, not merely a buzzword.
title: "Like Walking into an Empty Room"
title: Effects of Eurythmy Therapy on Stress Perception in Comparison with a Sports Intervention from the Subjects’ Perspective - A Qualitative Study
titleType: Subtitle
Creators: name: Berger, B.
name: Bertram, M.
name: Kanitz, J.
name: Pretzer, K.
name: Seifert, G.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Stress and health-related quality of life are important constructs used in treatment evaluation today. This study is based on a randomised controlled trial examining the stress-reducing effect of eurythmy therapy in comparison with step aerobics in 106 healthy but stressed subjects. The aim of the analysis was to characterise changes in the subjective perceptions of the participants. Methods. Interviews were conducted with 76 healthy adults, 36 () from the eurythmy group and 40 () from the step aerobics group both analysed by content analysis and phenomenologically. Results. The following categories were identified for the eurythmy therapy group: enabling a productive therapeutic response, emergence of a new perceptual space, reevaluation of the accustomed perception, and emergence of new options for action. Step aerobics places increased physical and intellectual demands. These are perceived differently as pleasant and relaxing, insufficiently challenging and/or boring, and too challenging and thus experienced as stress-enhancing. Conclusion. The qualitative results provided revealing insights into the profound effects of and subjective assignments of meaning to external and internal stress factors. Processes of mental reinterpretation leading to stress reduction can be stimulated by physical procedures such as eurythmy therapy.
Evaluation of OCR algorithms for images with different spatial resolutions and noises
Creators: name: Chen, Qing
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Engineering, Electronics and Electrical.
subject: Computer Science.

description: Various shaped-based image invariants are popular algorithms used in optical character recognitions (OCR), 3D object recognitions, and pattern recognitions. The shape-based image invariants can be divided into two different categories: boundary based image invariants such as Fourier descriptors and chain code; region-based image invariants including various moment-based invariants such as Hu's seven moment invariants and Zernike moments. This thesis introduced and evaluated different shape-based image invariants from the perspective of their invariance property to image transformations including scaling, translation, rotation and different image spatial resolutions. The influence caused by salt and pepper noises of different intensities is also analyzed. The image reconstruction ability of Zernike moments is implemented and discussed as well. An OCR engine is implemented with MATLAB scripts to perform the image feature extraction and image recognition. The OCR engine is also used in the overall performance evaluation of Fourier descriptors and Hu's seven moment invariants.
Mimesis, magic, manipulation: A study of the photograph in contemporary British and Canadian novels.
Creators: name: Bowen, Deborah.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Literature, Canadian (English).

description: The photograph is of interest to the writer because it is uniquely a product both of the realm of objective, physical reality and of the realm of artifice. Its ambiguous status as the physical emanation of a past referent endows it with an uneasy authority. It appears to offer assurances of identity and clarity; at the same time, it undermines the attempt to control experience by demonstrating that to freeze time and space is to render them obsolete. Thus the photograph can be seen as a metaphor for the life-giving and death-dealing enterprise of writing fictions. Moreover, because the photograph is a reflection of the past, private or public, a comparison of the use made of photographic images in the fictions of two different cultures, one older, one newer, may reveal differences in aesthetic between those two cultures. A theoretical dialectic for exploring the use made of the photograph in contemporary British and Canadian fiction can be constructed by comparing the thesis of Susan Sontag's On Photography (1977) with that of Roland Barthes' Camera Lucida (1980). Sontag is concerned with the camera as an instrument of power which victimizes its subjects; she sees the text as necessary to contextualize the image according to its function in time. Barthes understands the photograph's fragmentariness as potentially revelatory, and text as parasitic upon image. Where the Sontagian model emphasizes narrative contextualization and the photographer/writer as wielder of power, the Barthean model emphasizes a vertical hermeneutic of epiphanies and the spectator/reader as creator of meaning. A look at several contemporary British novelists who use photographic imagery (Julian Barnes, Graham Swift, Martin Amis, Fay Weldon, Penelope Lively, Anita Brookner, Timothy Mo, Salman Rushdie) suggests that these writers tend towards an ironical distancing of the photography, which is seen as parodic of traditional mimesis. Such novelists thus ascribe to and yet undermine Sontag's concern with narrative control. A number of contemporary Canadian writers (for instance, Margaret Atwood, Alice Munro, Margaret Laurence, Timothy Findley, Norman Levine, Diane Schoemperlen, Janette Turner Hospital, Michael Ondaatje) find within the photograph a representational magic that transcends boundaries of spatial and temporal logic. They share Barthes' belief in the intransigent value of appearances. An examination of these different writers' use of the photographic image thus provides a commentary upon their various understandings of the real, the fictive, and the relationship between the two.
Finding Long-COVID: temporal topic modeling of electronic health records from the N3C and RECOVER programs
Creators: name: Chew, Robert F.
name: Madlock-Brown, Charisse
name: Yoo, Yun Jae
name: Moffitt, Richard A.
name: Wei, Hannah
name: Pfaff, Emily R.
name: Haendel, Melissa A.
name: McGrath, Brenda M.
name: Wilkins, Kenneth J.
name: O’Neil, Shawn T.
name: French, Evan T.
name: Leese, Peter
name: Assaf, Gina S.
name: Zhou, Andrea
name: Loomba, Johanna
name: Chute, Christopher G.
name: Zareie, Parya
name: Davis, Hannah E.
name: McMurry, Julie A.
name: Lieberman, Michael
name: N3C and RECOVER Consortia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Post-Acute Sequelae of SARS-CoV-2 infection (PASC), also known as Long-COVID, encompasses a variety of complex and varied outcomes following COVID-19 infection that are still poorly understood. We clustered over 600 million condition diagnoses from 14 million patients available through the National COVID Cohort Collaborative (N3C), generating hundreds of highly detailed clinical phenotypes. Assessing patient clinical trajectories using these clusters allowed us to identify individual conditions and phenotypes strongly increased after acute infection. We found many conditions increased in COVID-19 patients compared to controls, and using a novel method to associate patients with clusters over time, we additionally found phenotypes specific to patient sex, age, wave of infection, and PASC diagnosis status. While many of these results reflect known PASC symptoms, the resolution provided by this unprecedented data scale suggests avenues for improved diagnostics and mechanistic understanding of this multifaceted disease.
Mapping the cytotoxic T-lymphocyte epitopes of Pichinde virus.
Creators: name: DeMille, Janet.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Biology, Microbiology.

description: One of the aims of this study was to determine whether the glycoproteins of Pichinde virus harbour any cytotoxic T-lymphocyte (CTL) epitopes on the murine haplotypes, H-2$\sp{\rm b}$ and H-2$\sp{\rm d}$ since, on neither of these MHC backgrounds are there any CTL epitopes on the nucleoprotein of this virus. Using a vaccinia virus recombinant, vvGPC, which expresses the full-length glycoprotein precursor (GPC) of Pichinde virus, standard chromium release CTL assays were performed. Three independent assays are shown for each of the haplotypes. In each of these assays for both of the haplotypes, it was observed that CTL derived against Pichinde virus did not recognize vvGPC-infected target cells nor did CTL derived against vvGPc recognize Pichinde-infected target cells. This indicates that no CTL were generated with either virus that might recognize the glycoproteins of Pichinde virus and, therefore, that the glycoproteins do not contain CTL epitopes on these murine MHC backgrounds. A second aim of this work was to compare the CTL epitopes of Pichinde wild-type virus with two temperature sensitive mutants derived from it. Both these mutants have been shown to be defective in their glycoprotein processing. The H-2$\sp{\rm d}$-restricted epitopes appear to be disrupted in TS13 as it is not recognized by Pichinde-specific CTL derived on this background. TS908 is not recognized by Pichinde-specific CTL on either haplotype suggesting that the wild-type virus' epitopes were probably disrupted during the derivation of this mutant. (Abstract shortened by UMI.)
Protective effects of acute exercise prior to doxorubicin on cardiac function of breast cancer patients : A proof-of-concept RCT
Creators: name: Kirkham, Amy Ashley
name: Shave, R. E.
name: Bland, K. A.
name: Bovard, J. M.
name: Eves, N. D.
name: Gelmon, Karen, 1953-
name: McKenzie, D. C.
name: Virani, S. A.
name: Stöhr, E. J.
name: Warburton, Darren E. R.
name: Campbell, K. L.
Publisher: name: The University of British Columbia
Year: 2018

description: Background: Preclinical studies have reported that a single treadmill session performed 24 h prior to doxorubicin provides cardio-protection. We aimed to characterize the acute change in cardiac function following an initial doxorubicin treatment in humans and determine whether an exercise session performed 24 h prior to treatment changes this response. Methods: Breast cancer patients were randomized to either 30 minutes of vigorous-intensity exercise 24 h prior to the first doxorubicin treatment (n=13), or no vigorous exercise for 72 h prior to treatment (control, n=11). Echocardiographically-derived left ventricular volumes, longitudinal strain, twist, E/A ratio, and circulating NT-proBNP, a marker of later cardiotoxicity, were measured before and 24-48 h after the treatment. Results: Following treatment in the control group, NT-proBNP, end-diastolic and stroke volumes, cardiac output, E/A ratio, strain, diastolic strain rate, twist, and untwist velocity significantly increased (all p≤0.01). Whereas systemic vascular resistance (p<0.01) decreased, and ejection fraction (p=0.02) and systolic strain rate (p<0.01) increased in the exercise group only. Relative to control, the exercise group had a significantly lower NT-proBNP (p<0.01) and a 46% risk reduction of exceeding the cut-point used to exclude acute heart failure. Conclusion: The first doxorubicin treatment is associated with acutely increased NT-proBNP, echocardiographic parameters of myocardial relaxation, left ventricular volume overload, and changes in longitudinal strain and twist opposite in direction to documented longer-term changes. An exercise session performed 24 h prior to treatment attenuated NT-proBNP release and increased systolic function. Future investigations should verify these findings in a larger cohort and across multiple courses of doxorubicin.
"Thank God for my Alcoholic:" Paradox, religion, and sacrificial scapegoating in Al-Anon
Creators: name: Lebovitz, Mara Partch
Publisher: name: Brandeis University
Year: 2024
Subjects: Anthropology of religion,
Anthropology of addiction
Rites and rituals
Illness and pathology
Charismatic Christianity
Religion of the self

description: Al-Anon Family Groups is a global mutual self-help program for the loved one's of alcoholics. The fellowship offers support for those who have been affected by another person's alcoholism. Through a working of the 12 Steps, the Al-Anon member is intended to heal from the wounds caused by their relationship with an alcoholic. This thesis explores how the commitment to the self-transformation that the 12 Steps brings spurs a religious dedication on the part of the Al-Anon members. This religious dogma is centered on the improvement of the self above all else, and often manifests itself at the violent expense of the member's alcoholic loved one.
Effects of indigenous beneficial microbes formulated as bio-fertilizer on the growth enhancement of tropical tree species, Neolamarckia cadamba
Creators: name: Ong, Wendy Han Sze
Publisher: name: Swinburne
Year: 2024

description: Chemical fertilizer is commonly applied to enhance the growth of Neolamarckia cadamba. However, chemical fertilizer is not user friendly to the surrounding environment. As an attempt to reduce the application of chemical fertilizer, carrier-based bio-fertilizer is introduced as an alternative fertilizer in this study. The effectiveness of biofertilizer in enhancing the growth of Neolamarckia cadamba seedlings were evaluated by conducting rhizopod assay, pot and field trials. Results from this study showed that dual combination of bio-fertilizer with half regime chemical fertilizer treatment had the effectiveness comparable to full regime chemical fertilizer treatment in enhancing the growth of Neolamarckia cadamba.
Epidelaxia Simon 1902
Creators: name: Asima, Ashraf
name: Caleb, John T. D.
name: Prasad, Gopal
name: Joseph, Mathew M.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Salticidae
Epidelaxia

description: Genus Epidelaxia Simon, 1902
Type species. Epidelaxia albostellata Simon, 1902
description: Published as part of Asima, Ashraf, Caleb, John T. D., Prasad, Gopal & Joseph, Mathew M., 2025, First record of Epidelaxia Simon, 1902 (Araneae: Salticidae) in India, with descriptions of two new species from the Western Ghats, pp. 595-600 in Zootaxa 5590 (4) on page 595, DOI: 10.11646/zootaxa.5590.4.10, http://zenodo.org/record/14953466
Competition in shoreline plant communities: A comparative approach.
Creators: name: Gaudet, Connie Lee.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Biology, Botany.

description: I tested the general hypothesis that competitive ability is an important determinant of pattern in shoreline plant communities. Specifically I tested four predictions generated from this general hypothesis: (1) the competitive performance of plant species is related to their distribution along natural gradients of fertility and standing crop; (2) the competitive performance of plant species is related to measurable plant traits; (3) the competitive performance of plant species is not significantly affected by changing nutrient supply; and (4) there is an "evolutionary trade-off" between nutrient stress tolerance of species and competitive performance that underlies the distribution of species along natural gradients of fertility and standing crop. These questions were posed at a broad, multi-species scale using comparative measures of competitive performance, stress tolerance, and morphology from over 40 shoreline plant species, and field distribution data from several natural shoreline communities in Ontario, Nova Scotia and Quebec. Results showed that the experimentally determined measure of the relative competitive performance of a species was significantly correlated with its position along natural gradients of fertility and standing crop; and with simple measurable plant traits, in particular above-ground biomass (r$\sb{\rm s}$ = 0.92; p .0001). Results also showed that the competitive performance of species under high and low nutrient conditions was significantly correlated after two growing seasons (r$\sb{\rm s}$ = 0.76; P .001); and that stress tolerance, measured as the relative biomass production of species under low nutrient conditions, was inversely correlated with competitive performance (r = $-$0.62, p .005).
Towards a Comprehensive Assessment of the Quality and Richness of the Europeana Metadata of food-related Images
Creators: name: Abgaz, Yalemisew
name: Dorn, Amelie
name: Preza Diaz, Jose Luis
name: Koch, Gerda
Publisher: name: Zenodo
Year: 2020

description: Towards a Comprehensive Assessment of the Quality and Richness of the Europeana Metadata of food-related Images
A-Spec: Conceptualizing Asexual Identity, Experience, and Phenomenological Form
Creators: name: Ghosh Lisbin, Maya Katyajini
Publisher: name: Brandeis University
Year: 2023
Subjects: asexuality
transitory identity
aromantic
Cultural Anthropology
Sociology of Sex and Gender

description: What precisely does it mean to be asexual? Though recent years have seen the emergence of a multiplicity of non-normative identities that take form along planes of gender and sexuality, topics on asexuality and asexual experience have minimal academic literature or representation in popular western media. The most widely accepted definition of asexuality is a lack of sexual attraction, however through conducting a series of long-form semi-structured interviews and an online survey of 2,000 self-identifying asexuals, this study reveals a more complex and comprehensive composition of asexual identities. This study explores asexuality through a variety of lenses and settings: the first chapter posits asexuality as a flexible identity that determines itself along scales of romantic and aromantic orientation, levels of libido, and forms of attraction. The second chapter explores the anarchic formation of asexual relationships and identities in the context of normative and compulsory sexualities. The third chapter explores the history of asexuality as construed as medical disorder, dysfunction, and disability, and the fourth chapter then positions asexuality within scopes of queer, feminist, and gendered politics. Through these varied themes and anthology of experiences, asexuality is proposed to be a transitory identity, a form of meta-category that is phenomenologically anti-binary. Asexuality can be understood as a means of deconstructing and reimagining the possibilities for relationships, care ethics, and the integrated social and sexual scripts that determine value in Western contemporary society.
Synchronization control of coded video streams: Algorithms and implementation.
Creators: name: Daami, Mourad.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Engineering, Electronics and Electrical.

description: In this thesis, we propose to blend the intra-media synchronization control of coded video streams with the decoding process. We present a client based application level buffer control scheme for coded video to maintain stream continuity, avoid data overflow and underflow conditions and compensate for possible clock drifts at the client. The control policy, referred to as the Predecoder Synchronization Controller (PSC), uses buffer occupancy as its main control parameter. Based on high and low buffer occupancy thresholds, overflow threats and starvation threats are detected. Time contraction (selective frame drop) and expansion concepts (selective frame repeat) are used to prevent these data overflow and starvation threats to become real conditions, respectively. PSC algorithms are specified for both Motion JPEG and MPEG. In the case of starvation or overflow threats, the PSC was found to smoothen the stream, avoiding long frame freeze and abrupt scene change situations, by creating localized variations in the rate of displayed stream. A prototype implementation of both MJPEG and MPEG PSCs was also carried out. (Abstract shortened by UMI.)
De l'intersubjectivité du concept d'hégémonie chez Cox et Keohane "Fur Ewig".
Creators: name: Paltiniseanu, Sorin Andreï.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Political Science, International Law and Relations.

description: La presente these de mai trise porte sur le concept d'hegemonie tel qu'il est utilise par Robert Keohane et Robert Cox. Tous deux se disent au moins partiellement influences par le philosophe Italien Antonio Gramsci (1891-1937). Cox se veut meme son heritier en ce qui a trait a une adaptation au domaine de l'economie politique internationale. La these deconstruit donc les theories des deux auteurs contemporains, en particulier leur reprise du concept d'hegemonic, point gramscien central, afin de demontrer que seul Cox peut vraiment etre consiere gramscien car il est le seul des deux a adopter une approche reflexive et intersubjective. Les theories des deux auteurs sont pour la cause confrontees a la pensee gramscienne qui pour la cause a ete mise en contexte historique. En effet, Gramsci est presente comme l'aboutissement d'un courant intersubjectif, ici rapidement reconstruit, commencant par Kent at passant par Hegel et Marx. Il en est donc deduit que Keohane ne peut fournir une variante partiellement originale et partiellement reflexive (interobjective plutot que intersubjective) du vieux concept realiste d'hegemonie. La deconstruction necessaire pour former sette demonstration nous permet aussi de ramasser des elements qui nous servent en conclusion a proposer une theorie tentative de la construction theorique; une ontologie metatheorique.
A survey of the relationship between accounting information content and auditing view with stock returns in the companies listed in Tehran Stock Exchange
Creators: name: وحید علیزاده ورکانی
name: حسین فیروزی
Publisher: name: figshare
Year: 2020
Subjects: subject: 180110 Criminal Law and Procedure
subject: FOS: Law

description: The purpose of this study was to investigate the relationship between the content of accounting information and audit opinion and the return on equity in companies admitted to the Tehran Stock Exchange. To test the hypotheses of a sample survey of 102 companies among the companies admitted to the Tehran Stock Exchange during the period Was selected from 2010 to 1394. Data needed for calculating the research variables have been extracted from Tadbir Pard and 'New Research' databases. The current research is descriptive-correlation research, based on the nature of the data, quantitative research based on Objectives are considered as applied research. The result of the first hypothesis test shows that the audited report has a positive and significant effect on the return on equity. The result of the test of the second hypothesis of the research shows that the audited report has a negative and significant effect on the stock returns. The results of the third hypothesis of the research show that the content of accounting information has a negative and significant effect on stock returns.
Anthro News, Winter 2022-Spring 2023
Creators: name: Washington State University Department Of Anthropology
Publisher: name: Washington State University
Year: 2023
Subjects: subject: Anthropology
subject: FOS: Sociology
subject: Research Methodology

description: Newsletter includes: Message from the Chair; Dating the Western Stemmed Tradition and Nimíipuu Traditional Subsistence Practices; Ackerman Research Fellowship Provides Undergraduate with Valuable Field Work Opportunities; Anna Jordan Selected to Receive Dissertation Fellowship Award; Faculty Publications and Updates; Tim Kohler Elected to National Academy of Sciences; Remembering Jeannette Mageo; Diane Curewitz, Anthropologist & Long-Time Staff Member, Retires; Fred Simoons’s Legacy Gift to Anthropology Excellence Fund Supports Array of Activities; Anthropology Graduate Organization News; Museum of Anthropology
High-density lipoprotein metabolism in the kidney.
Creators: name: Breznan, Dalibor.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Biology, Cell.

description: The kidney is believed to play a major role in the clearance and re-absorption of high density lipoprotein (HDL) particles from the blood. Experiments were undertaken to explore the specific sites of renal HDL metabolism in vivo and to investigate in vitro the factors that regulate the renal re-absorption of HDL by HKC-8 human proximal tubule (PT) cells. Perfusion of a rabbit renal artery with [3H]cholesteryl ester (CE) and 125I-protein labeled HDL particles showed that the kidneys are capable of filtering both apolipoprotein A-I (apoA-I) and whole HDL. A fluorescent microscopic study with the HKC-8 cells showed that the PT cells can bind and take up HDL particles. (Abstract shortened by UMI.)
Control of heart development in the Mexican axolotl (Ambystoma mexicanum).
Creators: name: Smith, Steven C.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Biology, Zoology.

description: The locations and migration of the embryonic primordia which form the heart are well known. However, the processes whereby the heart-forming mesoderm is induced, and the later mechanisms controlling the differentiation and morphogenesis of the heart are only poorly understood for any system. An important model system for studying heart induction and differentiation is the cardiac-lethal (c) mutant in the axolotl (Ambystoma mexicanum). Embryos homozygous for the c gene develop hearts which never begin to beat, become severely deformed due to the lack of circulation, and die shortly after hatching. The mutation was believed to affect the tissue responsible for heart induction, the anterior (pharyngeal) endoderm, rendering it incapable of supplying the appropriate inductive stimuli. The inductive failure hypothesis is largely based on an assumption. The assumption is that the timing of heart induction is the same in the axolotl as has been reported for another urodele species (Taricha torosa). As well, this hypothesis is based on the finding that wild-type heart mesoderm does not form beating hearts when transplanted into c/c embryos at late tailbud stages 28-29. On the basis of this evidence, it has been suggested that wild-type heart mesoderm does not receive the proper inductive signals in the mutant environment. However, it has also been suggested that the induction occurs much earlier in another species of Ambystoma than in T. torosa; the timing of the inductive process in the axolotl has never been determined. The presence of a specific activator and inhibitor of heart differentiation, both produced by the heart mesoderm itself, provides evidence that the later phases of heart formation (i.e. the organization of contractile proteins into functional sarcomeres, and possibly the early morphogenesis of the heart tube) are probably under the control of a two-morphogen reaction-diffusion system. Such systems have been demonstrated to control pattern formation in one invertebrate organism, and have been proposed to control morphogenesis in a variety of other systems. However, this study is the first direct, experimental evidence for a reaction-diffusion mechanism controlling the development of any vertebrate organ system. (Abstract shortened by UMI.)
Immune cell dynamics and the impact on the efficiency of transvascular antitumor interventional therapies in hepatocellular carcinoma patients
Creators: name: Li Y.-M
name: Sun Y.-D
name: Zhou C.-X
name: Zhang H
name: Han J.-J
Publisher: name: Frontiers Media SA
Year: 2024

description: Objective: This study investigates the impact of transvascular antitumor interventional therapies on immune cell dynamics and its correlation with disease control and progression-free survival (PFS) in hepatocellular carcinoma (HCC) patients. Methods: A single-center observational case-control study was conducted with 119 HCC patients. Transvascular antitumor interventional therapy were administered based on patient-specific evaluations. Peripheral blood samples were collected before and within 28 days after the first treatment to analyze lymphocyte subsets and other immune cells. Results: Higher counts of total white blood cells (WBCs), lymphocytes, monocytes, and basophils were significantly associated with disease control rate. Subgroup analysis revealed that abnormal BMI, diabetes, infection, and multiple lesions were significantly associated with T cell abnormalities. Age, abnormal BMI, hypertension, and abnormal AFP were linked to total T cell abnormalities. NK cells, B cells, Th cells, Tc/Ts cells, and CD4/CD8 ratios did not show significant differences in PFS probabilities. Conclusion: Higher counts of WBCs, lymphocytes, monocytes, and basophils, play a crucial role in the effectiveness of HCC interventional therapy.
The solubilities of oxygen in sulphuric acid solutions containing cupric and/or nickel sulphate at atmospheric and high pressures.
Creators: name: Li, Hanning.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Engineering, Chemical.

description: The solubilities of oxygen in aqueous solutions, containing sulphuric acid and copper or nickel sulphate, play an important role in a hydrometallurgical process for the recovery of copper called "pressure leaching". The experimental solutions were prepared as aqueous solutions containing 150 or 200 g/l of sulphuric acid and/or cupric cations of 30 g/l or 45 g/l and 0 or 15 g/l of nickel ions. The solubilities of oxygen in aqueous acid-salt solutions were determined at atmospheric and high pressures. The solubilities were measured in an absorption column. At an oxygen partial pressure of 0.5 MPa, the solubilities were measured by means of a two-step method. The solutions were saturated with oxygen at the temperatures of 373.15 K and 413.15 K at the oxygen partial pressure of 0.5 MPa. The oxygen was then desorbed at atmospheric pressure and 313.15 K. Densities and vapour pressures of solutions were also measured at temperatures from 298.15 K to 413.15 K for the determination of oxygen solubilities. The logarithm of oxygen solubilities in aqueous acid-salt solution is linearly related to molar concentration of bivalent cations and densities of acid-salt solutions. A simple model is then suggested to predict oxygen solubilities in the acid-salt solutions. This model has some advantages, compared with the models proposed by Setschenow and by Krevelen and Hoftijser. The effects of temperature and pressure on oxygen solubility are also discussed. In the solutions studied, the oxygen solubilities as a function of temperature follow a similar pattern to that in water. For different pressures, Henry's law is obeyed in the range of this research ($\le$5 atm). (Abstract shortened by UMI.)
Multiple photon reactions of organic molecules in solution.
Creators: name: Banks, Jeffrey T.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Chemistry, Physical.

description: This thesis presents the results from numerous studies on the multiple photon reactions of organic molecules in solution. The initial investigations on the selectivities of radical fragmentation reactions from ground and excited states required the use of both pulsed and continuous wave laser techniques. Laser flash photolysis techniques were used to determine the $\alpha,\alpha$-dimethoxybenzyl radicals undergo fragmentation from the excited state with a quantum yield which is close to one. High intensity laser-jet photolysis was used to determine the selectivities for the excited state fragmentation of unsymmetrically substituted $\alpha,\alpha$-dialkoxybenzyl. It was found that the excited radicals show no selectivity upon fragmentation whereas the ground state radical fragmentations are governed by the thermodynamic stability of the radical products. Lack of a suitable method for the production of semi-preparative amounts of multiple photon reaction products in our own laboratory led us to develop a new technique which utilizes pulsed lasers. By irradiating small droplets of solution with the focused output from a pulse laser we were able to induce multiple photon reactions with efficiencies which are comparable to the laser-jet technique. A direct comparison was made for the case of diphenylmethyl radicals in carbon tetrachloride and methanol. This method, dubbed laser-drop photolysis, was used, along with laser-flash photolysis techniques and conventional lamp irradiations, to investigate and compare the chemistry for several transient species from both the ground and excited states. A number of unique reaction pathways have been found to occur from the excited states of the transient intermediates. For example, ground state 1,1-diphenylethoxyl radicals undergo a neophyl-like rearrangement to yield 1-phenoxy-1-phenylethyl radicals. From the excited state this radical undergoes $\beta$-scission, a process which does not occur from the ground state radical. Irradiation of small drops of liquid by the focused output from high powered pulse lasers results in their destruction in a manner similar to the ablative photodecomposition of organic polymers. We have investigated the dynamics of the drop explosion by taking Polaroid photographs with a time resolution of $\sim$20 ns by using a second pulsed laser as the flash for the camera. The destruction of the drops occurs in the $\mu$s time scale and a model has been proposed which is consistent with the dynamics of drop explosion. Further, pyrene has been used in attempts to probe the temperature increase inside the drop just prior to its explosion.
Conformational Study of c-Src Using SortaseA-mediated Method
Creators: name: Yang, Han
Publisher: name: Brandeis University
Year: 2016
Subjects: c-Src

description: C-Src is a member of the non-receptor tyrosine kinase family and it is one of the major therapeutic targets due to its critical role in many cellular signaling pathways. The phosphorylation states of Tyrosine 416 and Tyrosine 527 in the catalytic domain of c-Src determine c-Src’s conformations and activities. Therefore an equilibrium exists between the species with different phosphorylation states on both Tyrosine residues. To investigate the population of each species at equilibrium, NMR is required. Unfortunatelyc-Src’s large size and low expression level poses a major obstacle. To resolve this a SortaseA-mediated method is adopted. This method allows for separate expression of the SH3SH2 domains and the catalytic domain of c-Src followed by a back-ligation, which makes the complete product. This back-ligated Src’sin vitro similarity to full-length Src is determined by Western blot, ATP-NADH coupled assay and NMR spectra. The insertion of the SortaseA motif LPETGG between Alanine 259 and Tryptophan 260 disrupts the interaction between the SH2-catalytic domain linker and the SH3 domain, which turns out to be critical for Src’s regulation. A new ligation scheme is proposed in which residue Threonine246 to Serine251 is substituted with the SortaseA motif. A full-length construct with the substitution is first acquired to determine whether it still interferes with the interaction between the linker and the SH3 domain. Current results of the ATP-NADH coupled assay and NMR spectra provide support for next-step back-ligation studies of this new construct.
Improving water quality with novel diagnostics : policy brief on the potential use of metagenomics for improved water quality testing
Creators: name: Harris, Leila
name: Prystajecky, Natalie
name: Henrich, Natalie
name: Holmes, Bev
name: Bakker, Karen J.
name: Dunn, Gemma
name: Feze, Ida Ngueng
name: Joly, Yann, 1973-
name: Knoppers, Bartha Maria
name: Birko, Stanislav
name: Dove, Edward S.
Publisher: name: The University of British Columbia
Year: 2018

Abstract
The augmented bushwalk: contemplative play across digital systems and natural worlds
Creators: name: Riley, Matthew
Publisher: name: Swinburne
Year: 2024

description: This research investigates how location-based augmented reality (AR) can alter our experience of bushland settings. While sound has been the primary mode of digitally mediating natural environments, the potential of augmented and mixed realities in these settings is less well understood. Through a practice-based methodology the research develops and analyses a prototype of an experimental mixed reality game titled Epiphyte. It proposes that contemplative play can be adopted to relate digital systems with the natural world, presenting five play design principles that demonstrate how location-based AR can support new place-making practices that re-shape our experience of bushland settings.
Feedfoward postural adjustments associated with unilateral rapid arm motion in children aged 4- and 5-years and 10- and 11-years.
Creators: name: McGregor, Jennifer.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Biology, Animal Physiology.

description: Very little is known of the development of the feedforward postural control mechanism. The purpose of this study was to identify differences in this system between two different stages of development. Two groups of ten children, aged 4- and 5-years old and 10- and 11-years-old took part in this study. Electromyographic (EMG) data from the right anterior deltoid, right and left erector spinae, right and left hamstring muscles and vertical ground reaction force data from the left and right foot as well as the total body, were collected during unilateral rapid forward arm movement about the shoulder in the sagittal plane. EMG and force data were examined for activity 100 ms prior to onset and 70 ms post movement onset. Onset latencies, probability of recruitment and recruitment order were determined for all postural muscles. Onset latencies of changes in the vertical ground reaction forces as well as coefficients of variation were determined for the vertical ground reaction forces. In general, the 4- and 5-year old children demonstrated a similar postural muscle recruitment order as the 10- and 11-year old children. However, the 4- and 5-year old children had a larger proportion of the postural muscles being activated before the movement onset than the 10- and 11-year old children did. The probability of the 4- and 5-year old children recruiting the left erector spinae muscle was significantly less than that of the 10- and 11-year old children. The 4- and 5-year old children demonstrated greater intra-subject variability about the vertical ground reaction forces than did the 10- and 11-year old children. These data suggest that with development, the feedforward postural used in preparation for a unilateral rapid arm raise becomes increasingly consistent. A shift in the feedforward postural adjustment goal from safety to efficiency is proposed.