cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Researching global citizenship education: Towards a critical approach
Creators: name: Schippling, Anne
Publisher: name: JSSE - Journal of Social Science Education
Year: 2020

description: Purpose: This article contains a reflection on researching in global citizenship education with a critical approach that aims to transcend the paradigm of methodological nationalism. Design/methodology/approach: Starting from outlining different dimensions of global citizenship (education), and looking at the current research situation in GCE, we propose a methodological turn that overcomes the nation-state paradigm as a base for critical research on GCE. Subsequently, using the concept of transnational capital as an analytical tool, we show – in the example of two biographical case studies in an international school in a large city of West Germany – how to put a critical research on GCE into action. Findings: The article demonstrates, on the one hand, how a critical approach to research aspects of global citizenship education can be taken, starting from a transnational research stance. On the other hand, it presents new perspectives and challenges for critical research in GCE.
description: JSSE - Journal of Social Science Education, Vol. 19 No. 4 (2020): Global education at crossroads
Transport in gapped bilayer graphene: the role of potential fluctuations
Creators: name: Zou, K.
name: Zhu, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We employ a dual-gated geometry to control the band gap Δin bilayer graphene and study the temperature dependence of the resistance at the charge neutrality point, RNP(T), from 220 to 1.5 K. Above 5 K, RNP(T) is dominated by two thermally activated processes in different temperature regimes and exhibits exp(T3/T)^{1/3} below 5 K. We develop a simple model to account for the experimental observations, which highlights the crucial role of localized states produced by potential fluctuations. The high temperature conduction is attributed to thermal activation to the mobility edge. The activation energy approaches Δ/2 at large band gap. At intermediate and low temperatures, the dominant conduction mechanisms are nearest neighbor hopping and variable-range hopping through localized states. Our systematic study provides a coherent understanding of transport in gapped bilayer graphene.
description: to appear in Physical Review B: Rapid Comm
Double -- photon exclusive processes with heavy quark -- heavy antiquark pairs in high-energy Pb-Pb collisions at LHC
Creators: name: Klusek-Gawenda, Mariola
name: Szczurek, Antoni
name: Machado, Magno
name: Serbo, Valeriy
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The cross section for exclusive heavy quark and heavy antiquark pair ($Q \bar Q$) production in peripheral ultrarelativistic heavy ion collisions is calculated for the LHC energy $\sqrt{s_{NN}}$ = 5.5 TeV. Here we consider only processes with photon--photon interactions and omit diffractive contributions. We present results in the impact parameter equivalent photon approximation (EPA) and compare some of them with results obtained by exact calculations of the Feynman diagrams in the momentum space. We include both $Q \bar Q$, $Q \bar Q g$ and $Q \bar Q q \bar q$ final states as well as photon single-resolved components. Realistic charge densities in nuclei were taken in the calculation. The different components give contributions of the same order of magnitude to the nuclear cross section. The cross sections found here are smaller than those for the diffractive photon-pomeron mechanism and larger than diffractive pomeron-pomeron discussed in the literature.
description: 12 pages, 9 figures, 5 tables
The effects of mindfulness and kindness meditation on teacher emotional abilities, compassion, and prosocial behavior
Creators: name: Floman, James L.
Publisher: name: University of British Columbia
Year: 2018

description: Teachers evidence high rates of occupational burnout and turnover. Accordingly, the present study evaluated the feasibility and acceptability of digital meditation practices for teachers. The effects of digital meditation on teacher affect and mindfulness, and on teacher emotion skills, compassion, and prosocial behavior also were examined. Participants were K-12 teachers from Western Canada (N = 121). Teachers were randomly assigned to mindfulness meditation (MM), kindness meditation (KM), or music relaxation (MR; active control) training for six weeks (approximately one hour a week). Teachers reported the digital MM, KM, and MR practices to be highly engaging, and moderately efficacious and enjoyable. Within-group increases in positive affect (d = 0.42) and mindfulness skills (ds = 0.42–0.45) were found in the MM group. Within-group reductions in negative affect (ds = -0.81, -0.83, -0.89) and stress (ds = -0.54, -0.49, -0.68) were found in the MM, KM, and MR groups, respectively. However, neither MM nor KM improved affect or mindfulness compared to the MR control. Thus, the within-group effects may (to some extent) reflect placebo effects and/or demand characteristics. Regarding the effects of training on emotion skills, compassion, and prosocial behavior, only one finding was observed. KM increased prosocial behavior (decreased altruistic punishment; d = -0.56) compared to MM in an online economic game. From pre-test to post-test KM reduced, whereas MM iatrogenically heightened, altruistic punishment. Exploratory analyses were conducted that also tested the effects of training on emotion skills, compassion, and prosocial behavior in the female subsample (n = 96) (the male subsample was too small – n = 22 – to conduct gender-by-group interactions or male-only analyses). In female teachers, KM promoted prosocial behavior in online economic games: KM versus the MR control increased altruistic giving (d = 0.57), and KM versus MM decreased altruistic punishment (d = -0.77). Overall, the feasibility and acceptability of digital meditation (and music relaxation) practices for teachers was supported. However, the efficacy of digital meditations as tools to foster adaptive teacher social-emotional behavior received limited support. Studies utilizing more intensive interventions that employ longitudinal designs are needed to determine the social-emotional efficacy of digital meditation for educators.
Global Citizenship Education for Global Citizenship?
Creators: name: Nygren, Thomas
name: Kronlid, David
name: Larsson, Esbjörn
name: Novak, Judit
name: Bentrovato, Denise
name: Wasserman, Johan
name: Welply, Oakleigh
name: , Anamika
name: Guath, Mona
Publisher: name: JSSE - Journal of Social Science Education
Year: 2020

description: Purpose: In this study, we explore students’ views and experiences in relation to education about, through, and forhuman rights, peace, and sustainability in the global north and south. We investigate what students after nine years of schooling see as central issues and productive actions linked to key elements of global citizenship education (GCE) to better understand the complexity of GCE in theory and practice. Design: We use a survey designed in line with theories of global citizenship education. Using a mixed methods approach, we analyse responses from 672 upper secondary school students, aged 16–19, in England, India, New Zealand, South Africa, and Sweden. Findings: We find that students in different contexts may experience global citizenship education very differently, even if they are all part of a global community with guidelines from UNESCO. Dimensions of human rights education, peace education, and education for sustainable development are evident in both the global north and south; yet, students in European contexts, namely in Sweden and England, for instance, appear to be taking away very different learnings. Overall, while students across the national samples have knowledge about human rights, peace, and sustainability, they seem to struggle to identify activities for human rights, peace, and sustainability. We find a vernacularisation of GCE, highlighting a diversity of methods and cultural contexts linked to students’ experiences from education. Research limitations: This study is limited to a few schools in selected countries; thus, our findings may not be generalisable on a national or global level. Practical implications: Students across our diverse sample highlight the importance of education to promote global goals. Findings indicate that more focus on education for global citizenship is necessary if schooling is to work in line with international recommendations. Similarities and differences in students’ knowledge and understanding about peace, human rights, and sustainability call for differentiated and localised approaches in attempts to reach common and shared goals.
description: JSSE - Journal of Social Science Education, Vol. 19 No. 4 (2020): Global education at crossroads
Steuerungsprozesse in der Selbstorganisation am Beispiel Restaurant Zent
Creators: name: Walker, Lorenz
Publisher: name: Hochschule für Angewandte Psychologie FHNW
Year: 2023
Subjects: subject: Selbstorganisation
subject: New Work
subject: Heterarchie
subject: Gruppendynamik
subject: Gastegewerbe
subject: 150 - Psychologie
subject: 330 - Wirtschaft

description: In selbstorganisierten Betrieben und Teams müssen Prozesse zum Erhalt des Teams und zur Entwicklung der Organisation gesteuert werden. Das Restaurant Zent in Bern arbeitet aktuell in einem Organisationsmodell mit 3 Profilen, welche hierarchisch gleichgestellt sind. In dieser Bachelor-Thesis wird die Fragestellung erforscht, wie Prozesse im Restaurant Zent gesteuert werden. Dabei werden Kontext-, Team- und Selbststeuerungsprozesse aus einer gruppendynamischen Perspektive untersucht. Zur Untersuchung wurde als erstes ein standardisierter Fragebogen zur Erfassung der Teamreflexivität eingesetzt. Als Hauptteil der Erhebung wurden zwei Gruppendiskussionen mit je 4 Personen durchgeführt. Mit einem qualitativen Ansatz wurden die Resultate thematisch und sequenzanalytisch analysiert und diskutiert. Daraus ergab sich, dass sowohl die Kontextsteuerung, wie auch grosse Teile der Teamsteuerung, vom Profil 3 übernommen werden. In beiden Steuerungsarten können jedoch Entscheide von den Mitarbeitenden widerrufen werden. Im Bereich der Selbststeuerung wird bereits über die Zusammenarbeit reflektiert. Die Reflexionen finden hauptsächlich informell statt. Aktuell fehlt dem Betrieb eine Möglichkeit, die impliziten und expliziten Rollen, Normen und Regeln formell zu reflektieren und anschliessend zu legitimieren. Weiter konnte gezeigt werden, dass die Aufteilung auf Profile nicht als Hierarchie im Sinne eines Machtanspruchs wahrgenommen wird, sondern als klare Verteilung der Verantwortung. Das Beispiel zeigt, dass mit neuen Arbeitsformen auch neue Aufgaben und Anforderungen auftauchen, welche bisher nur spärlich bekannt sind.
Structural effects in the nuclide distributions of the residues of highly excited systems
Creators: name: Napolitani, P.
name: Rejmund, F.
name: Tassan-Got, L.
name: Ricciardi, M. V.
name: Kelic, A.
name: Schmidt, K. -H.
name: Yordanov, O.
name: ignatyuk, A. V.
name: villagrasa, C.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: New data from GSI on the production-cross-section for fragmentation of the systems 56Fe+p and 56Fe+Ti at 1 A GeV revealed the appearance of even-odd staggering in the cross-section distribution for chains of isotopes with given N-Z. The staggering is strongly enhanced for the chain N=Z, it reduces as the production moves away from the N=Z chain, and it reverses for the most neutron-rich odd-A residues. These phenomena, observed in the residues of rather violent reactions, are related to structural effects in the level-densities below the particle-emission threshold.
description: 4 pages, 2 figures. 10th Nuclear Physics Workshop of Marie and Pierre Curie, 24 - 28 Septembre 2003, Kazimierz Dolny (Poland)
Hyperbolic Deformation Applied to S = 1 Spin Chains - Scaling Relation in Excitation Energy -
Creators: name: Ueda, Hiroshi
name: Nakano, Hiroki
name: Kusakabe, Koichi
name: Nishino, Tomotoshi
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We investigate excitation energies of hyperbolically deformed S = 1 spin chains, which are specified by the local energy scale f_j^{~} = \cosh j λ, where j is the lattice index and λis the deformation parameter. The elementary excitation is well described by a quasiparticle hopping model, which is also expressed in the form of hyperbolic deformation. It is possible to estimate the excitation gap Δin the uniform limit λ\rightarrow 0, by means of a finite size scaling with respect to the system size N and the deformation parameter λ.
description: 5 pages, 4 figures
Streaming Multimedia Information Using the Features of the DVB-S Card
Creators: name: Arsinte, Radu
name: Lupu, Eugen
Publisher: name: arXiv
Year: 2011
Subjects: subject: Multimedia (cs.MM)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: This paper presents a study of audio-video streaming using the additional possibilities of a DVB-S card. The board used for experiments (Technisat SkyStar 2) is one of the most frequently used cards for this purpose. Using the main blocks of the board's software support it is possible the implement a really useful and full functional system for audio-video streaming. The streaming is possible to be implemented either for decoded MPEG stream or for transport stream. In this last case it is possible to view not only a program, but any program from the same multiplex. This allows us to implement
description: 4 pages, 5 figures
Quantum open systems approach to the dynamical Casimir effect
Creators: name: Lombardo, F. C.
name: Mazzitelli, F. D.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We analyze the introduction of dissipative effects in the study of the dynamical Casimir effect. We consider a toy model for an electromagnetic cavity that contains a semiconducting thin shell, which is irradiated with short laser pulses in order to produce periodic oscillations of its conductivity. The coupling between the quantum field in the cavity and the microscopic degrees of freedom of the shell induces dissipation and noise in the dynamics of the field. We argue that the photon creation process should be described in terms of a damped oscillator with nonlocal dissipation and colored noise.
description: 12 pages, to appear in the Proceedings of the "Wokshop on Quantum Nonstationary Systems", Brasilia 2009 (Special Issue, Physica Scripta)
Exploring linguistic indicators of social collaborative group engagement
Creators: name: Jeitziner, Loris Tizian
name: Paneth, Lisa
name: Rack, Oliver
name: Zahn, Carmen
name: Wulff, Dirk U.
Publisher: name: International Society of the Learning Sciences
Year: 2023
Subjects: subject: Natural Language Processing
subject: Quality of Collaborative Group Engagement
subject: Computer-supported Collaborative Learning
subject: 400 - Sprache, Linguistik
subject: 004 - Computer Wissenschaften, Internet
subject: 150 - Psychologie

description: This study takes a NLP approach to measuring social engagement in CSCL-learning groups. Specifically, we develop linguistic markers to capture aspects of social engagement, namely sentiment, responsiveness and uniformity of participation and compare them to human ratings of social engagement. We observed small to moderate links between NLP-markers and human ratings that varied in size and direction across the different groups. We discuss measurement and prediction of social collaborative group engagement using natural language processing.
An industrial internet architecture based on SDN and fog computing
Creators: name: He, Junxiong
Publisher: name: University of British Columbia
Year: 2018

description: In traditional industrial networks, conventional distributed switches adopt traditional optimization algorithms to equally share bandwidth among contending flows, such as transmission control protocol (TCP) congestion control algorithm. However, a large number of machines, goods, control systems and information systems will be interconnected in industrial Internet. As a result, when an emergency occurs, traffic will increase considerably and network congestion will occur. In the worst-case scenario, the machines may not function properly (e.g. some robot-arms cannot respond fast enough to complete the intended tasks). In this thesis, based on the features of software defined network (SDN), network status information of each SDN switch is extracted by an SDN controller through a centralized control architecture. The information is also processed by a fog computing server through network utility maximization fabric (NUMFabric) using the weight max-min fairness algorithm. Our testbed results show that when an emergency occurs, the new architecture can reduce the bandwidth allocation recovery time by more than 350 times that of the traditional TCP. Moreover, by identifying the requirement of industrial Internet and the features of Internet of Things (IoT), an integrated architecture can be designed based on SDN, fog computing, cloud computing, object linking and embedding for process control unified architecture (OPC UA) standard. This thesis includes key aspects of analysis, design and implementation for industrial Internet architecture with short recovery time. It is demonstrated that network entities such as the fog computing server, the SDN Ryu controller, SDN OpenFlow switches and optical sensors can function together. The centralized parameter acquiring method for NUMFabric using the weight max-min fairness algorithm can also perform bandwidth allocation through OPC UA standard and OpenFlow protocol on our testbed.
Phosphorus-modification of Pt-catalysts  boosts the catalytic performance in  cycloalkane dehydrogenation
Creators: name: Ellert, Abelina
name: Herold, Felix
name: Hutzler, Andreas
name: Janssens, Ton V. W.
name: Vennestrøm, Peter
name: Wasserscheid, Peter
name: Schühle, Patrick
Publisher: name: Zenodo
Year: 2023

description: In this study, novel P-modified Pt-catalysts supported on Al2O3 are synthesized, characterized and evaluated regarding their activity in cycloalkane dehydrogenation. The preparation involves two different methods, liquid and gas phase P-modification. Analytical techniques such as XRD, XPS and TEM shed light on the nature of platinum and phosphorus in the catalyst. The catalytic performance of the materials in dehydrogenation of perhydro benzyltoluene (H12-BT) is evaluated and compared to non-doped Pt-catalysts. This work reveals that P-modification can boost the activity of Pt/Al2O3 in cycloalkane dehydrogenation.
Heterointerface effects on the charging energy of shallow D- ground state in silicon: the role of dielectric mismatch
Creators: name: Calderon, M. J.
name: Verduijn, J.
name: Lansbergen, G. P.
name: Tettamanzi, G. C.
name: Rogge, S.
name: Koiller, Belita
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Donor states in Si nanodevices can be strongly modified by nearby insulating barriers and metallic gates. We report here experimental results indicating a strong reduction in the charging energy of isolated As dopants in Si FinFETs relative to the bulk value. By studying the problem of two electrons bound to a shallow donor within the effective mass approach, we find that the measured small charging energy may be due to a combined effect of the insulator screening and the proximity of metallic gates.
description: 7 pages, 6 figures
On the exact solution of the mixed-spin Ising chain with axial and rhombic zero-field splitting parameters
Creators: name: Danco, M.
name: Strecka, J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Ground-state phase diagram of the mixed spin-$1/2$ and spin-$1$ Ising chain with axial and rhombic zero-field splitting parameters is exactly calculated within the framework of the transfer-matrix method. It is shown that the rhombic zero-field splitting parameter prefers the magnetically ordered phase instead of the disordered phase.
description: 5 pages, 2 figures
Decoherence and wave function collapse
Creators: name: Omnès, Roland
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The possibility of consistency between the basic quantum principles of quantum mechanics and wave function collapse is reexamined. A specific interpretation of environment is proposed for this aim and applied to decoherence. When the organization of a measuring apparatus is taken into account, this approach leads also to an interpretation of wave function collapse, which would result in principle from the same interactions with environment as decoherence. This proposal is shown consistent with the non-separable character of quantum mechanics.
The experiences of female long-distance labour commuters from the City of Kelowna to the Regional Municipality of Wood Buffalo
Creators: name: Nagy, Stephanie
Publisher: name: University of British Columbia
Year: 2018

description: Research conducted on female long-distance labour commuters (LDLC) in male-dominated resource extraction industries is limited particularity within a Canadian context. Female LDLCs’ experiences may be d1istinct from male LDLCs in important ways that can create specific barriers and challenges for female workers. This thesis examines therefore the experiences of female LDLCs acknowledging ideologies of hegemonic masculinities and neoliberalism. This study is spatially situated in the City of Kelowna as a home community and within the Regional Municipality of Wood Buffalo as a work site. Drawing on principals of Poststructural Feminist Geography, this study was conducted as an exploratory case study utilizing a sequential mixed methods approach. Data from this study was analyzed through critical discourse analysis. Recruitment and data collection for this thesis took place between November 2015 and October 2016 through a survey with 9 female LDLCs and 5 in-depth interviews. The study reveals push/pull forces influencing female LDLCs’ decisions to participate in this type of work. Further, the results indicate that female LDLCs face many implicit vs. explicit barriers working in male-dominated resource extraction industries: constant need to prove abilities and competencies, increased individualism and competition from precarious work, conflicts between motherhood and resource extraction work, and hegemonic stereotypes. The study additionally demonstrates that participants cope by putting up with challenges through strength and endurance, adopting a work-centric mentality demonstrated through work ethic, proving competencies, and invisibility through avoidance or disengagement. This study yields policy and practical recommendations aimed at improving female LDLCs’ work experiences: greater family friendly policies, a need for increased diversity in all sectors of resource extraction, more social support, and effective avenues for support and reporting of discrimination or harassment. Recommendations originating from this study also contribute to broader discussion on gender and labour with acknowledgement of various existing systemic and structural inequalities imbued under the contours of neoliberal ideology and hegemonic masculinities. This research is not representative of the majority of female LDLC in Canada, but instead focuses on a few in-depth experiences that act as a starting point for understanding and challenging existing barriers based on embedded inequalities.
On the benefits of using dedicated models in validation processes for behavioral specifications: Supplement
Creators: name: Daun, Marian
name: Brings, Jennifer
name: Krajinski, Lisa
name: Weyer, Thorsten
Publisher: name: Zenodo
Year: 2019

description: Provides the experiment material (i.e. the questionnaire, models shown, questions asked) for the experiment reported in the paper "On the benefits of using dedicated models in validation processes for behavioral specifications").
The effect of bars and transient spirals on the vertical heating in disk galaxies
Creators: name: Saha, Kanak
name: Tseng, Yao Huan
name: Taam, Ronald E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The nature of vertical heating of disk stars in the inner as well as the outer region of disk galaxies is studied. The galactic bar (which is the strongest non-axisymmetric pattern in the disk) is shown to be a potential source of vertical heating of the disk stars in the inner region. Using a nearly self-consistent high-resolution N-body simulation of disk galaxies, the growth rate of the bar potential is found to be positively correlated with the vertical heating exponent in the inner region of galaxies. We also characterize the vertical heating in the outer region where the disk dynamics is often dominated by the presence of transient spiral waves and mild bending waves. Our simulation results suggest that the non-axisymmetric structures are capable of producing the anisotropic heating of the disk stars.
description: 14 pages, 20 figures, Accepted for publication in ApJ
The complete Dirichlet-to-Neumann map for differential forms
Creators: name: Sharafutdinov, Vladimir
name: Shonkwiler, Clayton
Publisher: name: arXiv
Year: 2010
Subjects: subject: Differential Geometry (math.DG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 58A14, 58J32, 57R19

description: The Dirichlet-to-Neumann map for differential forms on a Riemannian manifold with boundary is a generalization of the classical Dirichlet-to-Neumann map which arises in the problem of Electrical Impedance Tomography. We synthesize the two different approaches to defining this operator by giving an invariant definition of the complete Dirichlet-to-Neumann map for differential forms in terms of two linear operators Φ and Ψ. The pair (Φ, Ψ) is equivalent to Joshi and Lionheart's operator Π and determines Belishev and Sharafutdinov's operator Λ. We show that the Betti numbers of the manifold are determined by Φ and that Ψ determines a chain complex whose homologies are explicitly related to the cohomology groups of the manifold.
description: 16 pages
Ground-state properties of the spin-1/2 Heisenberg-Ising bond alternating chain with Dzyaloshinskii-Moriya interaction
Creators: name: Strecka, J.
name: Galisova, L.
name: Derzhko, O.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Ground-state energy is exactly calculated for the spin-1/2 Heisenberg-Ising bond alternating chain with the Dzyaloshinskii-Moriya interaction. Under certain condition, which relates a strength of the Ising, Heisenberg and Dzyaloshinskii-Moriya interactions, the ground-state energy exhibits an interesting nonanalytic behavior accompanied with a gapless excitation spectrum.
description: 6 pages, 3 figures
Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL, and interleukin-12
Creators: name: Altwaijry, Najla
name: Somani, Sukrut
name: Parkinson, John A.
name: Tate, Rothwelle J.
name: Keating, Patricia
name: Warzecha, Monika
name: Mackenzie, Graeme R.
name: Leung, Hing Y.
name: Dufès, Christine
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The possibility of using gene therapy for the treatment of prostate cancer is limited by the lack of intravenously administered delivery systems able to safely and selectively deliver therapeutic genes to tumors. Given that lactoferrin (Lf) receptors are overexpressed on prostate cancer cells, we hypothesized that the conjugation of Lf to generation 3-diaminobutyric polypropylenimine dendrimer would improve its transfection and therapeutic efficacy in prostate cancer cells. In this study, we demonstrated that the intravenous administration of Lf-bearing DAB dendriplexes encoding TNFα resulted in the complete suppression of 70% of PC-3 and 50% of DU145 tumors over one month. Treatment with DAB-Lf dendriplex encoding TRAIL led to tumor suppression of 40% of PC-3 tumors and 20% of DU145 tumors. The treatment was well tolerated by the animals. Lf-bearing generation 3-polypropylenimine dendrimer is therefore a highly promising delivery system for non-viral gene therapy of prostate cancer.
Geology of Mammoth Cave National Park, Kentucky
Creators: name: Crawford, Matthew M.
name: Olson, Rickard A.
name: Toomey, Rickard S.
name: Scoggins, Lillian J.
Publisher: name: Kentucky Geological Survey, University of Kentucky
Year: 2008

description: Abstract:
Mammoth Cave National Park in south-central Kentucky was authorized as a national park in 1926 and was fully established in 1941 to protect the cave system, scenic landscape, and diverse flora and fauna. The park contains 52,830 acres and most of the longest recorded cave system in the world, with more than 390 miles of mapped passages as of 2013. Even though Mammoth Cave is famous, people are often unaware of the park's intricate connection to the outside region. This poster shows the geology of Mammoth Cave and the interconnected issues that are important to the park and its visitors.
This cooperative project between the Kentucky Geological Survey and the National Park Service is intended for park visitors, educators, park staff, and anyone who enjoys Mammoth Cave National Park. Digital geologic mapping and recent advances in geographic information system (GIS) technologies help the National Park Service meet federal mandates and distribute data sets, maps, and other products that are valuable to all who enjoy national parks.
For more information, please visit the Mammoth Cave National Park Web site at www.nps.gov/maca. You can also find information at the Mammoth Cave International Center for Science and Learning, a research and education center for the park. If you're interested in obtaining digital geologic and other GIS data, visit the National Park Service Datastore at www.science.nature.nps.gov/nrdata. The geologic map data in this publication were developed from Davidson (2006), Mullins (2006a, b), Thompson (2006a, b), and Toth (2006a-d).
Copyright: © 2017, University of Kentucky, Kentucky Geological Survey
Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors
Creators: name: Su, Chia-Yu
name: Chen, Michael
name: Chen, Ling-Chun
name: Ho, Yuan-Soon
name: Ho, Hsiu-O
name: Lin, Shyr-Yi
name: Chuang, Kuo-Hsiang
name: Sheu, Ming-Thau
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 60506 Virology
subject: FOS: Biological sciences

description: Anti-mPEG/anti-human epidermal growth factor receptor 2 (HER2) bispecific antibodies (BsAbs) non-covalently bound to a docetaxel (DTX)-loaded mPEGylated lecithin-stabilized micellar drug delivery system (LsbMDDs) were endowed with active targetability to improve the chemotherapeutic efficacy of DTX. DTX-loaded mPEGylated LsbMDDs formulations were prepared using lecithin/DSPE-PEG(2K or 5K) nanosuspensions to hydrate the thin film, and then they were subjected to ultrasonication. Two BsAbs (anti-mPEG/anti-DNS or anti-HER2) were simply mixed with the LsbMDDs to form BsAbs-LsbMDDs formulations, respectively, referred as the DNS-LsbMDDs and HER2-LsbMDDs. Results demonstrated that the physical characteristics of the BsAbs-LsbMDDs were similar to those of the plain LsbMDDs but more slowly released DTX than that from the LsbMDDs. Results also showed that the HER2-LsbMDDs suppressed the growth of HER2-expressing MCF-7/HER2 tumors, increasing the amount taken up via an endocytosis pathway leading to high drug accumulation and longer retention in the tumor. In conclusion, the BsAbs-LsbMDDs preserved the physical properties of the LsbMDDs and actively targeted tumors with a drug cargo to enhance drug accumulation in tumors leading to greater antitumor activity against antigen-positive tumors.
Spin relaxation times of two-dimensional holes from spin sensitive bleaching of intersubband absorption
Creators: name: Schneider, Petra
name: Kainz, Josef
name: Ganichev, Sergey
name: Danilov, Sergey
name: Rössler, Ulrich
name: Wegscheider, Werner
name: Weiss, Dieter
name: Prettl, Wilhelm
name: Belkov, Vassilij
name: Glazov, M.
name: Golub, Leonid E.
name: Schuh, Dieter
Publisher: name: Universität Regensburg
Year: 2004
Subjects: subject: aluminium compounds, gallium arsenide, III-V semiconductors, two-dimensional hole gas, semiconductor quantum wells, absorption coefficients, spin-spin relaxation, spin polarised transport
subject: 530 Physik
subject: 73.25.+i; 72.25.Dc; 78.66.Fd; 68.65.Fg; 78.67.De; 76.60.Es

description: We present spin relaxation times of two-dimensional holes obtained by spin sensitive bleaching of the absorption of infrared radiation in p-type GaAs/AlGaAs quantum wells (QWs). It is shown that the saturation of intersubband absorption of circularly polarized radiation is mainly controlled by the spin relaxation time of the holes. The saturation behavior has been determined for different QW widths and in a wide range of temperatures with the result that the saturation intensity substantially decreases with narrowing of the QWs. Spin relaxation times are derived from the measured saturation intensities by making use of calculated (linear) absorption coefficients for direct intersubband transitions. It is shown that spin relaxation is due to the D'yakonov–Perel' mechanism governed by hole–hole scattering. The problem of selection rules is addressed.
Pluriversal possibilities and challenges for Global Education in Northern Europe
Creators: name: Pashby, Karen
name: Da Costa, Marta
name: Sund, Louise
Publisher: name: JSSE - Journal of Social Science Education
Year: 2020

description: Purpose: This paper considers the relevance of critical and decolonial approaches to global education in northern Europe through theoretical and empirical research. Methodology: We present a case for an approach that engages the modern/colonial dynamic (Mignolo, 2000; Andreotti, 2014) and pluriversality (Mignolo & Walsh, 2018). We conducted a project involving workshops with secondary teachers in England, Finland, and Sweden centred on Andreotti’s (2012) HEADSUP tool. We recorded discussions at the workshops and individual interviews after applying the tool in practice. Findings: Teachers are both strategic and reticent in how they take up colonialism when teaching global issues. Wider political contexts and teachers’ and students’ own experiences with colonialism and racialisation are very much part of how ethical global issues are framed, unpacked, and responded to in classrooms. While there are some significant challenges evident, several teachers deepened their approach and co-produced a teacher resource supporting the application of HEADSUP to classroom practice.
description: JSSE - Journal of Social Science Education, Vol. 19 No. 4 (2020): Global education at crossroads
The impact of oncogenic kras on redox balance to support cellular transformation and tumorigenicity
Creators: name: Lim, Jonathan Kah Meng
Publisher: name: University of British Columbia
Year: 2018

description: Activating mutations in KRAS are found in ~90% of pancreatic cancers, ~40% of colorectal cancers, and ~30% of non-small cell lung cancers. To date no effective therapies exist for cancer patients of this genetic subset, driving an impetus to develop novel therapeutic agents that target KRAS or downstream effectors of KRAS. The impact of oncogenic KRAS on the intracellular redox balance and its contribution to tumorigenicity is still controversial. Many studies have reported that oncogenic RAS enhances intracellular reactive oxygen species (ROS) levels, while recent major work by several groups described that oncogenic RAS drives antioxidant programs, which are necessary to mediate tumorigenicity. It is therefore critical to further explore the role of oncogenic KRAS on redox balance and its impact on cellular transformation and tumorigenicity. To this end, I utilized whole transcriptome profiling in normal and oncogenic KRAS-transformed cells to identify redox pathways regulated by oncogenic KRAS to support tumorigenicity. Whole transcriptome analysis revealed that the Cystine/Glutamate Transporter, xCT had the highest positive fold change in KRAS-transformed cells in response to exogenous oxidative stress. xCT is responsible for the cellular uptake of cystine, the rate-limiting precursor in the synthesis of glutathione (GSH), which is the major intracellular antioxidant. As such, I postulated that oncogenic KRAS signaling promotes transcriptional upregulation of xCT to support cellular transformation and tumorigenicity by preventing oxidative stress. Notably, inhibition of xCT in KRAS-transformed cells exacerbates oxidative stress causing cell death and also impaired cellular transformation and tumorigenicity, providing the first evidence that xCT is a downstream effector of oncogenic KRAS signaling. In addition, I found clinical evidence for the upregulation of xCT in subsets of cancer with activating mutations in KRAS and for the association of high xCT expression with poorer patient outcome. Finally, I delineated a novel mechanism of xCT activation involving the cooperative interaction between ETS1, which lies downstream of the RAS-MAPK signaling cascade, and ATF4, a known regulator of xCT. Overall, my findings demonstrate that oncogenic KRAS signaling modulates cellular redox balance by upregulating xCT expression to promote transformation and tumorigenicity.
COMPARATIVE ANALYSIS OF ONLINE REVIEW PLATFORMS: IMPLICATION IN ELECTRONIC SERVICE QUALITY FOR VIDEO PLAYERS AND EDITOR APPS (YOUTUBE AND TIKTOK)
Creators: name: NURVITA TRIANASARI
name: MAYA ARIYANTI
name: LIDYA SRI MULYANI
Publisher: name: Zenodo
Year: 2023
Subjects: Sentiment Analysis, Topic Modelling, Regression Linear, Correlation, Service Quality, Media Sharing Network.

description: Abstract
This study uses sentiment analysis, topic modeling, pearson correlation, and linear regression to identify the critical improvements that video-sharing platforms, particularly YouTube and TikTok, should make in the future to better handle user reviews. Given that video sharing provides viewers with an extremely immersive and engaging experience, its growing significance in relation to user feedback is becoming progressively apparent for companies. We initially preprocess 21,365 user reviews using Naïve Bayes classification, and we divide them into seven groups according to the dimensions of e-service quality: efficiency, responsiveness, system availability, compensation, fulfillment, contact, and privacy. The accuracy percentages for TikTok and YouTube came out as 80.33% and 75.56%, accordingly, indicating excellent performance in evaluating the quality of both platforms. Sentiment analysis revealed a higher prevalence of negative sentiment on TikTok and YouTube. Then, topic modeling based on Latent Dirichlet Allocation (LDA) evaluates the sentiment of the topic as well as the model of the topics discussed. The purpose of this research is to help both companies and individuals map public opinion toward a certain topic by analyzing the sentiment of the text and creating a topic model. We also measure the relationship between service quality using user sentiment and ratings, then predict future user ratings using predictive analysis methods such as linear regression. Regarding the classification of dimensions, we effectively draw attention to three dimensions— efficiency, fulfillment, and system availability —that are deemed important in the comparison between YouTube and TikTok. Then, the positive and significant relationship between service quality using user sentiment and ratings.
Quantum interference in exciton-Mn spin interactions in a CdTe semiconductor quantum dot
Creators: name: Trojnar, A.
name: Korkusinski, M.
name: Kadantsev, E.
name: Hawrylak, P.
name: Goryca, M.
name: Kazimierczuk, T.
name: Kossacki, P.
name: Wojnar, P.
name: Potemski, M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We show theoretically and experimentally the existence of a new quantum interference(QI) effect between the electron-hole interactions and the scattering by a single Mn impurity. Theoretical model, including electron-valence hole correlations, the short and long range exchange interaction of Mn ion with the heavy hole and with electron and anisotropy of the quantum dot, is compared with photoluminescence spectroscopy of CdTe dots with single magnetic ions. We show how design of the electronic levels of a quantum dot enable the design of an exciton, control of the quantum interference and hence engineering of light-Mn interaction.
description: 11 pages, 4 figures, submitted to PRL
Number-conserving master equation theory for a dilute Bose-Einstein condensate
Creators: name: Schelle, Alexej
name: Wellens, Thomas
name: Delande, Dominique
name: Buchleitner, Andreas
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We describe the transition of $N$ weakly interacting atoms into a Bose-Einstein condensate within a number-conserving quantum master equation theory. Based on the separation of time scales for condensate formation and non-condensate thermalization, we derive a master equation for the condensate subsystem in the presence of the non-condensate environment under the inclusion of all two body interaction processes. We numerically monitor the condensate particle number distribution during condensate formation, and derive a condition under which the unique equilibrium steady state of a dilute, weakly interacting Bose-Einstein condensate is given by a Gibbs-Boltzmann thermal state of $N$ non-interacting atoms.
CdWO4 scintillating bolometer for Double Beta Decay: Light and Heat anticorrelation, light yield and quenching factors
Creators: name: Arnaboldi, C.
name: Beeman, J. W.
name: Cremonesi, O.
name: Gironi, L.
name: Pavan, M.
name: Pessina, G.
name: Pirro, S.
name: Previtali, E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We report the performances of a 0.51 kg CdWO4 scintillating bolometer to be used for future Double Beta Decay Experiments. The simultaneous read-out of the heat and the scintillation light allows to discriminate between different interacting particles aiming at the disentanglement and the reduction of background contribution, key issue for next generation experiments. We will describe the observed anticorrelation between the heat and the light signal and we will show how this feature can be used in order to increase the energy resolution of the bolometer over the entire energy spectrum, improving up to a factor 2.6 on the 2615 keV line of 208Tl. The detector was tested in a 433 h background measurement that permitted to estimate extremely low internal trace contaminations of 232Th and 238U. The light yield of gamma/beta, alpha and neutrons is presented. Furthermore we developed a method in order to correctly evaluate the absolute thermal quenching factor of alpha particles in scintillating bolometers.
description: 8 pages 7 figures
Particle reacceleration by compressible turbulence in galaxy clusters: effects of reduced mean free path
Creators: name: Brunetti, G.
name: Lazarian, A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Direct evidence for in situ particle acceleration mechanisms in the inter-galactic-medium (IGM) is provided by the diffuse Mpc--scale synchrotron emissions observed from galaxy clusters. It has been proposed that MHD turbulence, generated during cluster-cluster mergers, may be a source of particle reacceleration in the IGM. Calculations of turbulent acceleration must account self-consistently for the complex non--linear coupling between turbulent waves and particles. This has been calculated in some detail under the assumption that turbulence interacts in a collisionless way with the IGM. In this paper we explore a different picture of acceleration by compressible turbulence in galaxy clusters, where the interaction between turbulence and the IGM is mediated by plasma instabilities and maintained collisional at scales much smaller than the Coulomb mean free path. In this regime most of the energy of fast modes is channeled into the reacceleration of relativistic particles and the acceleration process approaches a universal behaviour being self-regulated by the back-reaction of the accelerated particles on turbulence itself. Assuming that relativistic protons contribute to several percent (or less) of the cluster energy, consistent with the FERMI observations of nearby clusters, we find that compressible turbulence at the level of a few percent of the thermal energy can reaccelerate relativistic electrons at GeV energies, that are necessary to explain the observed diffuse radio emission in the form of giant radio halos.
description: 8 pages, 3 figures. Accepted in MNRAS (October 28, 2010)
Effect of Spatial Charge Inhomogeneity on 1/f Noise Behavior in Graphene
Creators: name: Xu, Guangyu
name: Torres, Carlos M.
name: Zhang, Yuegang
name: Liu, Fei
name: Song, Emil B.
name: Wang, Minsheng
name: Zhou, Yi
name: Zeng, Caifu
name: Wang, Kang L.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Scattering mechanisms in graphene are critical to understanding the limits of signal-to-noise-ratios of unsuspended graphene devices. Here we present the four-probe low frequency noise (1/f) characteristics in back-gated single layer graphene (SLG) and bilayer graphene (BLG) samples. Contrary to the expected noise increase with the resistance, the noise for SLG decreases near the Dirac point, possibly due to the effects of the spatial charge inhomogeneity. For BLG, a similar noise reduction near the Dirac point is observed, but with a different gate dependence of its noise behavior. Some possible reasons for the different noise behavior between SLG and BLG are discussed.
description: 28 pages, 3 figures + 3 supplement figures