cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Pre-operative prediction of BCR-free survival with mRNA variables in prostate cancer
Creators: name: O’Donnell, Autumn
name: Cronin, Michael
name: Moghaddam, Shirin
name: Wolsztynski, Eric
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 49
subject: Mathematical sciences

description: Technological innovation yielded opportunities to obtain mRNA expression data for prostate cancer (PCa) patients even prior to biopsy, which can be used in a precision medicine approach to treatment decision-making. This can apply in particular to predict the risk of, and time to biochemical recurrence (BCR). Most mRNA-based models currently proposed to this end are designed for risk classification and post-operative prediction. Effective preoperative prediction would facilitate early treatment decision-making, in particular by indicating more appropriate therapeutic pathways for patient profiles who would likely not benefit from a systematic prostatectomy regime. The aim of this study is to investigate the possibility to leverage mRNA information pre-operatively for BCR-free survival prediction. To do this, we considered time-to-event machine learning (ML) methodologies, rather than classification models at a specific survival horizon. We retrospectively analysed a cohort of 135 patients with clinical follow-up data and mRNA information comprising over 26,000 features (data accessible at NCBI GEO database, accession GSE21032). The performance of ML models including random survival forest, boosted and regularised Cox models were assessed, in terms of model discrimination, calibration, and predictive accuracy for overall, 3-year and 5-year survival, aligning with common clinical endpoints. Results showed that the inclusion of mRNA information could yield a gain in performance for pre-operative BCR prediction. ML-based time-to-event models significantly outperformed reference nomograms that used only routine clinical information with respect to all metrics considered. We believe this is the first study proposing pre-operative transcriptomics models for BCR prediction in PCa. External validation of these findings, including confirmation of the mRNA variables identified as potential key predictors in this study, could pave the way for preoperative precision nomograms to facilitate timely personalised clinical decision-making.
Valarmathi - Video - 1 - MSCs-Control-24 Hours-10X Ph.AVI
Creators: name: Fuseler, John W.
Publisher: name: figshare
Year: 2016
Subjects: Stem Cells

description: Live Cell Imaging and Analysis Image Acquisition Live cell imaging and Image acquisition set up were exactly followed as per our previously published protocols (Fuseler and Valarmathi, 2012). “Following creation of the wound area in the MSCs monolayer cultures, the MatTek dishes were immediately mounted on the stage of a Zeiss Axiovert 200M inverted microscope in a Zeiss M200 humidified incubator chamber, and maintained at 37oC and 5% CO2 during the course of observations and the collection of images. An appropriate area of the margin of the wound was selected for imaging. Images were collected by time-lapse microscopy using phase contrast optics (10X, N.A. 0.25 PH-1 Achroplan objective) and a CCD camera (Hamamatsu ORCA-ER) controlled by Kinetic Imaging Image Acquisition Software (AQM Advance-6) software at a rate of 10 frames per hour for a total period of 24 hours. The incident light during exposure of the image was filtered with 546 nm green interference filter, and exposure times were maintained constant at 23.15 ms for all kinetic cell migration experiments,” (Fuseler and Valarmathi, 2012).   Measurement of MSCs Cellular Movements and Displacements The effect of exogenous NO on directed cellular movement was determined by measurement of the displacement of individual MSCs into the wound region. The changes in the displacement of individual MSCs were determined by frame-by-frame analysis with the AQM Advance-6 software, and were expressed as the mean of the final displacement of the MSCs from the wound margin at 24 hours. On an average, 50 cells were measured for each experimental group treated with SNAP (SN-1 and SN-2) and their corresponding control groups.
A High Speed Particle Phase Discriminator (PPD-HS) for the classification of airborne particles, as tested in a continuous flow diffusion chamber
Creators: name: Mahrt, Fabian
name: Wieder, Jörg
name: Dietlicher, Remo
name: Smith, Helen R.
name: Stopford, Chris
name: Kanji, Zamin A
Publisher: name: ETH Zurich
Year: 2019

description: A new instrument, the High Speed Particle Phase Discriminator (PPD-HS) developed at the University of Hertfordshire, for sizing individual cloud hydrometeors and determining their phase is described herein. PPD-HS performs an in-situ analysis of the spatial intensity distribution of near forward scattered light for individual hydrometeors yielding shape properties. Discrimination of spherical and aspherical particles is based on an analysis of the symmetry of the recorded scattering patterns. Scattering patterns are collected onto two linear detector arrays, reducing the complete 2D scattering pattern to scattered light intensities captured onto two linear, one dimensional strips of light sensitive pixels. Using this reduced scattering information, we calculate symmetry indicators that are used for particle shape and ultimately phase analysis. This reduction of information allows for detection rates of a few hundred particles per second.

Here, we present a comprehensive analysis of instrument performance using both spherical and aspherical particles, generated in a well-controlled laboratory setting using a Vibrating Orifice Aerosol Generator (VOAG) and covering a size range of approximately 3–32 micron. We use supervised machine learning to train a random forest model on the VOAG data sets that can be used to classify any particles detected by PPD-HS. Classification results show that the PPD-HS can successfully discriminate between spherical and aspherical particles, with misclassification below 5 % for diameters > 3 micro meter. This phase discrimination method is subsequently applied to classify simulated cloud particles produced in a continuous flow diffusion chamber setup. We report observations of small, near-spherical ice crystals at early stages of the ice nucleation experiments, where shape analysis fails to correctly determine the particle phase. Nevertheless, in case of simultaneous presence of cloud droplets and ice crystals, the introduced particle shape indicators allow for a clear distinction between these two classes independent of optical particle size. We conclude that PPD-HS constitutes a powerful new instrument to size and discriminate phase of cloud hydrometeors and thus study microphysical properties of mixed-phase clouds, that represent a major source of uncertainty in aerosol indirect effect for future climate projections.
description: Atmospheric Measurement Techniques Discussions
description: ISSN:1867-8610
The distribution, dominance patterns and ecological niches of plankton functional types in Dynamic Green Ocean Models and satellite estimates
Creators: name: Vogt, Meike
name: Hashioka, Taketo
name: Payne, Mark R.
name: Buitenhuis, Erik T.
name: Le Quéré, Corinne
name: Alvain, Séverine
name: Aita, Maki Noguchi
name: Bopp, Laurent
name: Doney, Scott C.
name: Hirata, Takafumi
name: Lima, Ivan
name: Sailley, S.
name: Yamanaka, Y.
Publisher: name: ETH Zurich
Year: 2013

description: We compare the spatial and temporal representation of phytoplankton functional types (pPFTs) in four different Dynamic Green Ocean Models (DGOMs; CCSM-BEC, NEMURO, PISCES and PlankTOM5) to derived phytoplankton distributions from two independent satellite estimates, with a particular focus on diatom distributions. Global annual mean surface biomass estimates for diatoms vary between 0.23 mmol C m−3 and 0.77 mmol C m−3 in the models, and are comparable to a satellite-derived estimate (0.41 mmol C m−3). All models consistently simulate a higher zonal mean diatom biomass contribution in the high latitudes than in the low latitudes, but the relative diatom contribution varies substantially between models with largest differences in the high latitudes (20% to 100% of total biomass). We investigate phytoplankton distribution in terms of annual and monthly mean dominance patterns, i.e. the distribution of locations where a given PFT contributes more than 50% to total biomass. In all models, diatoms tend to dominate large areas of the high latitudes of both hemispheres, and the area of the surface ocean dominated by diatoms is significantly higher in the models than in the satellite estimates. We estimate the realized ecological niches filled by the dominant pPFT at each location as a function of annual mean surface nitrate concentration (NO3), sea surface temperature (SST), and mixed layer depth. A general additive model (GAM) is used to map the probability of dominance of all pPFTs in niche and geographic space. Models tend to simulate diatom dominance over a wider temperature and nutrient range, whereas satellites confine diatom dominance to a narrower niche of low-intermediate annual mean temperatures (annual mean SST < 10 °C), but allow for niches in different ranges of surface NO3 concentrations. For annual mean diatom dominance, the statistically modelled probability of dominance explains the majority of the variance in the data (65.2–66.6%). For the satellite estimates, the explained deviance is much lower (44.6% and 32.7%). The differences in the representation of diatoms among models and compared to satellite estimates highlights the need to better resolve phytoplankton succession and phenology in the models. This work is part of the marine ecosystem inter-comparison project (MAREMIP).
description: Biogeosciences Discussions, 10
description: ISSN:1810-6277
description: ISSN:1810-6285
The Impact of Examination Modalities and Higher Education Structures on Individual Study Paths – A Survey Experiment
Creators: name: Bauer, Victoria A.
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2022
Subjects: subject: study success
subject: survey experiment
subject: study behaviour
subject: examination modalities
subject: discrete choice
subject: higher education
subject: Studienerfolg
subject: Surveyexperiment
subject: Studienverhalten
subject: Prüfungsbedingungen
subject: Discrete Choice Experiment
subject: Hochschulen
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie

description: Due to the high demand for academically qualified personnel, ensuring study success is of social and economic importance. In this context, the effect of institutional regulations of study and examination organizations on study behaviour is surprisingly unexplored, despite new institutionalism being a major paradigm in sociological research. We present the structure of a survey experiment aiming to gain insights into the mechanisms about which degree of obligation in examination modalities encourages academic success and which hinders it. The study belongs to the BMBF-funded (Bundesministerium für Bildung und Forschung) project "Bedeutung des institutionellen Kontextes von Studienabbruch und Langzeitstudium (BiK)", which consists of Leibniz University Hannover, the German Centre for Higher Education Research and Science Studies (DZHW) and the University of Mannheim/Mannheim Centre for European Social Research (MZES). The project seeks to investigate the effect of the study-related institutional context on student dropout, long-term study and study paths at the three levels of federal state, university and study programme.
Prehistoric Rock-art at Ashover School and Discoveries elsewhere in the Peak District.
Creators: name: Barnatt, John W
name: Robinson, Frank
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 123, 1-28
description: The paper documents the discovery of prehistoric rock art at Ashover School on the fringe of the Peak District, including two elaborately decorated slabs with unusual motifs. It also updates the corpus of prehistoric rock art in the Peak District, including several new discoveries from the past twenty years and making new observations on some previously known examples. Includes
Neolithic pits, Howden Moor, Hope Woodlands: Excavation and Fieldwalking.
Creators: name: Bevan, Bill
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 123, 29-49
description: Four patches of burnt stones and charcoal were observed in the eroded surface of the reservoir bed and subsequently excavated. Three were identified as sub-circular pits, the fourth being a superficial, probably natural feature in which burned material had been trapped. Three possible stakeholes were also identified. Charcoal from the fills of two features was radiocarbon dated, indicating that the pits were created and filled during the mid-third millennium BC. Fieldwalking in the immediate area recovered fourteen pieces of flint and twelve pieces of chert. Includes
Global ocean carbon uptake: Magnitude,variability and trends
Creators: name: Wanninkhof, Rik H.
name: Park, Geunha
name: Takahashi, Taro
name: Sweeney, Colm
name: Feely, Richard A.
name: Nojiri, Yukihiro
name: Gruber, Nicolas
name: Doney, Scott C.
name: McKinley, Galen A.
name: Lenton, Andrew
name: Le Quéré, Corinne
name: Heinze, Christoph
name: Schwinger, Jörg
name: Graven, Heather D.
name: Khatiwala, Samar P.
Publisher: name: ETH Zurich
Year: 2012

description: Estimates of the anthropogenic global-integrated sea-air carbon dioxide (CO2) fluxfrom 1990 to 2009, based on different models and measurements, range from−1.4to−2.6 PgC yr−1. The median values of anthropogenic CO2for each method showbetter agreement and are:−1.9 for Pg C yr−1for numerical ocean general circulation hind cast models (OGCMs) with parameterized biogeochemistry;−2.1 PgC yr−1for at-mospheric inverse models;−1.9 PgC yr−1for global atmospheric constraints based onO2/ N2ratios for 1990–2000; and−2.4 PgC yr−1for oceanic inverse models. An up-dated estimate of this anthropogenic CO2flux based on a climatology of sea-air partialpressure of CO2differences (∆pCO2) (Takahashi et al., 2009) and a bulk formulation of gas transfer with wind speed for year 2000 is−2.0 PgC yr−1. Using this∆pCO2climatology and empirical relationships ofpCO2with sea-surface temperature (SST)anomalies (Park et al., 2010a), the interannual variability of the contemporary CO2flux is estimated to be 0.20Pg C yr−1(1σ) from 1990 through 2009. This is similar tothe variability estimated by the OGCMs of 0.16 Pg Cyr−1but smaller than the interannual variability from atmospheric inverse estimates of 0.40Pg C yr−1. The variability islargely driven by large-scale climate re-organizations. The decadal trends for differentmethods range from−0.13 (Pg Cyr−1) decade−1to−0.50 (Pg Cyr−1) decade−1. TheOGCMs and the data based sea-air CO2flux estimates show smaller uptakes and ap-preciably smaller decadal trends than estimates based on changes in carbon inventory suggesting that methods capable of resolving shorter timescales are showing a slow-ing of the rate of ocean CO2uptake. It is not clear if this large difference in trend is amethodological issue or a real natural feedback
description: Biogeosciences Discussions, 9
description: ISSN:1810-6277
description: ISSN:1810-6285
Polished stone axe and flintwork from Fissure Cave, Hartle Dale, near Bradwell.
Creators: name: Gilks, John A
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 123, 50-58
description: Descriptions and discussion of stone artefacts and debitage found during excavation of the cave in 1963, along with a more general discussion of the site and its possible usage. Includes
A flint dagger found near Curzon Lodge, Longcliffe, Brassington.
Creators: name: Makepeace, G A
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 123, 59-62
description: Description of a lanceolate flint dagger, as well as other worked flints and sherds of prehistoric and Roman-British pottery found in the same area.
The full greenhouse gases budget of Africa: Synthesis, uncertainties and vulnerabilities: Synthesis, uncertainties and vulnerabilities
Creators: name: Valentini, Riccardo
name: Arneth, Almuth
name: Bombelli, Antonio
name: Castaldi, Simona
name: Cazzolla Gatti, Roberto
name: Chevallier, Frédéric
name: Ciais, Philippe
name: Grieco, Elisa
name: Hartmann, Jens
name: Henry, Matieu
name: Houghton, R.A.
name: Jung, Martin
name: Kutsch, Werner L.
name: Malhi, Yadvinder Singh
name: Mayorga, Emilio
name: Merbold, Lutz
name: Papale, Dario
name: Peylin, Philippe
name: Raymond, Peter A.
name: Santini, Monia
name: Sitch, Stephen A.
name: Vaglio Laurin, Gaia
name: van der Werf, Guido R.
name: Williams, Christopher R.
name: Scholes, Robert J.
Publisher: name: ETH Zurich
Year: 2013

description: This paper, developed under the framework of the RECCAP initiative, aims at providingimproved estimates of the carbon and GHG (CO2, CH4and N2O) balance of continentalAfrica. The various components and processes of the African carbon and GHG bud-get were considered, and new and available data derived by different methodologies (based on inventories, ecosystem fluxes, models, and atmospheric inversions) wereintegrated. The related uncertainties were quantified and current gaps and weaknessin knowledge and in the monitoring systems were also considered in order to provideindications on the future requirements. The vast majority of the results seem to agreethat Africa is probably a small sink of carbon on an annual scale, with an average value of−0.61±0.58 PgCyr−1. Nevertheless the emissions of CH4and N2O may turn Africainto a source in terms of CO2equivalents. At sub-regional level there is a significantspatial variability in both sources and sinks, mainly due to the biome’s differences andthe different anthropic impacts, with southern Africa as the main source and centralAfrica, with its evergreen tropical forests, as the main sink. Emissions from land use change in Africa are significant (around 0.32±0.05 PgCyr−1) and even higher than thefossil fuel ones; this is a unique feature among all the continents. In addition there canbe significant carbon losses from land even without changes in the land use (forest),as results from the impact of selective logging. Fires also play a significant role, with1.03±0.22 PgCyr−1of carbon emissions, mainly (90 %) originated by savanna and woodland burning. But whether fire carbon emissions are compensated by CO2up-take during the growing season, or are a non-reversible loss of CO2, remains unclear.Most of these figures are subjected to a significant interannual variability, on the orderof±0.5 PgCyr−1in standard deviation, accounting for around 25 % of the year-to-yearvariation in the global carbon budget. These results, even if still highly uncertain, show the important role that Africa playsin the carbon cycle at global level, both in terms of absolute values and variability
description: Biogeosciences Discussions, 10
description: ISSN:1810-6277
description: ISSN:1810-6285
Contextualising Monuments; the exceptional potential of the middle Trent valley.
Creators: name: Loveday, Roy
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 124, 1-12
description: Discussion of the spatial distribution of Middle and Late Neolithic monuments such as cursuses and henges in the Trent Valley, and the tendency of such monuments to be found in clusters. The author discusses regional networks as indicated by stone axes, river crossings and the evidence provided by old land surfaces preserved in the cursus interiors.
Excavation of a prehistoric clearance cairn and ritual pits on Sir William Hill, Eyam Moor, 2000.
Creators: name: Wilson, Arthur
name: Barnatt, John W
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 124, 13-63
description: The excavation of a small cairn at the top end of a cairnfield on Sir William Hill, on moorland above Eyam, has found evidence for early agricultural clearance of Neolithic or very early Bronze Age date. The cairn was subsequently enlarged over three pits with evidence of ritual deposition. These contained placed stones including a saddle quern, sherds from four Beakers, flint scrapers, and a deposit of calcined bone. Associated charcoal gave two radiocarbon dates centred around 2050 BC. A number of scrapers were also placed at the cairn during or after the enlargement. Includes
Sleep-wake behaviors associated with cognitive performance in middle-aged participants of the Hispanic Community Health Study/Study of Latinos
Creators: name: Mossavar-Rahmani, Yasmin
name: Sotres-Alvarez, Daniela
name: Krafty, Robert T
name: Redline, Susan
name: Ramos, Alberto
name: Patel, Sanjay R
name: Stone, Katie L
name: Gallo, Linda C
name: Gonzalez, Hector M
name: Zhang, Gehui
name: Tarraf, Wassim
name: Gujral, Swathi
name: Fischer, Dorothee
name: Rodakowski, Juleen
name: Lamar, Melissa
name: Smagula, Stephen F
Publisher: name: Elsevier
Year: 2024

description:
OBJECTIVES: Many sleep-wake behaviors have been associated with cognition. We examined a panel of sleep-wake/activity characteristics to determine which are most robustly related to having low cognitive performance in midlife. Secondarily, we evaluate the predictive utility of sleep-wake measures to screen for low cognitive performance. METHODS: The outcome was low cognitive performance defined as being >1 standard deviation below average age/sex/education internally normalized composite cognitive performance levels assessed in the Hispanic Community Health Study/Study of Latinos. Analyses included 1006 individuals who had sufficient sleep-wake measurements about 2years later (mean age=54.9, standard deviation= 5.1; 68.82% female). We evaluated associations of 31 sleep-wake variables with low cognitive performance using separate logistic regressions. RESULTS: In individual models, the strongest sleep-wake correlates of low cognitive performance were measures of weaker and unstable 24-hour rhythms; greater 24-hour fragmentation; longer time-in-bed; and lower rhythm amplitude. One standard deviation worse on these sleep-wake factors was associated with ∼20%-30% greater odds of having low cognitive performance. In an internally cross-validated prediction model, the independent correlates of low cognitive performance were: lower Sleep Regularity Index scores; lower pseudo-F statistics (modellability of 24-hour rhythms); lower activity rhythm amplitude; and greater time in bed. Area under the curve was low/moderate (64%) indicating poor predictive utility. CONCLUSION: The strongest sleep-wake behavioral correlates of low cognitive performance were measures of longer time-in-bed and irregular/weak rhythms. These sleep-wake assessments were not useful to identify previous low cognitive performance. Given their potential modifiability, experimental trials could test if targeting midlife time-in-bed and/or irregular rhythms influences cognition.
Modeling and Simulation at FDA -- Lecture at Leuven
Creators: name: Morrison, Tina
Publisher: name: figshare
Year: 2016
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences

description: This presentation was shared with the academic groups in the biomechanics group at KU Leuven, a member university of the Virtual Physiological Human Institute.

This presentation covers topics of M&S at FDA and more specific aspects of M&S at the Center for Devices and Radiological Health.
生物種の分布推定における標本情報等の活用
Creators: name: Ishihama, Fumiko
Publisher: name: figshare
Year: 2016
Subjects: subject: 50202 Conservation and Biodiversity
subject: FOS: Biological sciences
subject: 50101 Ecological Impacts of Climate Change
subject: FOS: Earth and related environmental sciences
subject: Ecology

description: 本文書は、日本生態学会第63回大会で開催されたシンポジウム「保全科学が挑む情報のギャップ」での著者の講演の一部に基づいて執筆されたものです。本文書は投稿・審査中の未定稿であり、あくまでも参考としてご活用ください。論文が掲載された後は、それを引用してご活用ください。This document is a pre-print, being under the process of submission and review for publication in a journal. Thus, please cite it as an article of the journal, once the document is accepted and published.要約：博物館の標本情報や市民調査による観察情報などに代表される、不在情報がない分布データは、在のみデータと総称される。GBIF（Global Biodiversity Information Facility）などの公開データベースの整備により、在のみデータは分布推定に広く用いられるようになり、その成果が保全生物学分野でも幅広く応用されている。しかし、在のみデータに基づく分布推定に際しては、不在情報がないことに起因する特有の注意点が生じる。特に注意が必要なのが、サンプリングバイアスの存在と、バイアスに対応した偽不在（pseudo-absence）の選び方、推定値の性質、推定精度の評価指標の値の解釈のしかたである。在のみデータに基づく分布推定を、保全対策に適切に活用するためには、これらの注意点とその対処法を十分に理解することが欠かせない。これらの注意点と対処法に関して、蓄積されつつある海外での報告事例を紹介する。
Presence-only data is a distribution data which lack absence information. Typical examples of presence-only data are herbarium specimen and chance observation data by civil survey. Presence-only data are widely used for distribution estimation due to establishment of open database such as GBIF (Global Biodiversity Information Facility), and obtained distribution predictions are used for various conservation applications. However, the lack of absence requires various specific cautions in estimating distribution based on presence-only data. Special attentions are needed about the existence of sampling biases, way of selecting pseudo-absence in correspondence to biases, the nature of estimated values, and interpretation of values of indices for evaluating estimation accuracies. For appropriate application of distribution estimations based on presence-only data in conservation measures, deep understanding about these cautions and techniques to cope with these problems are indispensable. I review accumulating international reports on these cautions and coping techniques.
Response of δ13C in plant and soil respiration to a water pulse
Creators: name: Salmon, Yann
name: Buchmann, Nina
name: Barnard, Romain L.
Publisher: name: ETH Zurich
Year: 2011

description: Stable carbon isotopes have been used to assess the coupling between changes in environmental conditions and the response of soil or ecosystem respiration, usually by studying the time-lagged response of δ13C of respired CO2 (δ13CR) to changes in photosynthetic carbon isotope discrimination (Δi). However, the lack of a systematic response of δ13CR to environmental changes in field studies stresses the need to better understand the mechanisms to this response. 

We experimentally created a wide range of carbon allocation and respiration conditions in Fagus sylvatica mesocosms, by growing saplings under different temperatures and girdling combinations. After a period of drought, a water pulse was applied and the short-term responses of δ13C in soil CO2 efflux (δ13CRsoil) and δ13C in aboveground plant respiration (δ13CRabove) were measured, as well as leaf gas exchange rates and soil microbial biomass δ13C responses. 

Both δ13CRsoil and δ 13CRabove values of all the trees decreased immediately after the water pulse. These responses were not driven by changes in Δi, but rather by a fast release of C stored in roots and shoots. Changes in δ13CRsoil associated with the water pulse were significantly positively correlated with changes in stomatal conductance, showing a strong impact of the plant component on δ13CRsoil. However, three days after the water pulse in girdled trees, changes in δ13CRsoil were related to changes in microbial biomass δ13C, suggesting that changes in the carbon source respired by soil microorganisms also contributed to the response of δ13CRsoil. 

Our study shows that improving our mechanistic understanding of the responses of δ13CR to changes in environmental conditions requires the understanding of not only the plant's physiological responses, but also the responses of soil microorganisms and of plant-microbial interactions.
description: Biogeosciences Discussions, 8
description: ISSN:1810-6277
description: ISSN:1810-6285
title: 11 - Entretien avec le vieil azmari Mulu’aläm Adägä : chant de type zäläsäña
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: chant

description: Bälay Mäkkätä chante un chant de type zäläsäña.
title: Automated Mobility on Demand – A Transportation Concept for Vienna ́s Metropolitan Area
Creators: name: Schmidt, Thomas
Publisher: name: TU Wien
Year: 2020
Subjects: subject: Automated Mobility
subject: Mobility on Demand
subject: Electric Vehicles
subject: Traffic Reduction
subject: Car Sharing

description: In this paper, the impact of intermodal mobility on our current mobility behaviour is analysed. To be more specific, this research will evaluate the effects of an autonomous mobility on demand (AMoD) service with electric vehicles, and whether it would help to decrease overall congestion and emissions by internal combustion vehicles.At first, the current mobility behaviour of the observed region is analysed together with the demand pattern to understand how a future mobility concept would need to be designed and what requirements it should serve. Adding on, the concept of ride sharing, intermodal mobility, as well as the technological aspects of autonomous vehicles and battery-electric-vehicles are explained to give a better understanding of the underlying principles. Furthermore, the literature review will give an outline of the already existing research regarding this topic. This will demonstrate that there is already some research in this area, however, due to significant differences between the papers, it appears that there is still room for new relevant research.For the research of this paper, a macroscopic mobility simulation was used as methodology in order to assess the effect of an AMoD ride sharing service. This was done for the district of Mödling in the metropolitan region of Vienna. This region shares borders with Vienna and is one of the regions from where most commuters travel towards and from Vienna. Also, due to its features it would serve as role model for further regions around Vienna or even the city itself.For the simulation, three different scenarios were created to better analyse the significance of ride sharing. All three simulations show that it would be possible to decrease the current private vehicle fleet to maximum 10% with ride sharing, but still serving full demand. Other positive effects include a lower total mileage of the vehicles, fewer vehicles on the roads at any given time what leads to less congestion, and most importantly, it would lead to lower emission by the vehicles. This would be especially true if the sharing fleet consisted of battery-electric-vehicles only. Therefore, electric autonomous ride sharing can be seen as a future mobility trend that helps to decrease vehicle fleet size, congestion, and emissions. This will help cities to become cleaner, safer, and less congested by vehicles. Not only during rush hours for commuters, but during the whole day as the service can be used at any time for any reason within the given area of operation. Thus, private transportation would get more efficient and sustainable in the future by the introduction of AMoD ride sharing.
Gap-filling strategies for annual VOC flux data sets
Creators: name: Bamberger, Ines
name: Hörtnagl, Lukas
name: Walser, Mario
name: Hansel, Armin
name: Wohlfahrt, Georg
Publisher: name: ETH Zurich
Year: 2013

description: Up  to  now  the  limited  knowledge  about  the  ex-change of volatile organic compounds (VOCs) between thebiosphere  and  the  atmosphere  is  one  of  the  factors  whichhinders more accurate climate predictions. Complete long-term flux data sets of several VOCs to quantify the annualexchange and validate recent VOC models are basically notavailable.  In  combination  with  long-term  VOC  flux  mea-surements the application of gap-filling routines is inevitablein  order  to  replace  missing  data  and  make  an  importantstep towards a better understanding of the VOC ecosystem–atmosphere exchange on longer timescales.We performed VOC flux measurements above a mountainmeadow  in  Austria  during  two  complete  growing  seasons(from snowmelt in spring to snow reestablishment in late au-tumn) and used this data set to test the performance of fourdifferent gap-filling routines, mean diurnal variation (MDV),mean gliding window (MGW), look-up tables (LUT) and lin-ear  interpolation  (LIP),  in  terms  of  their  ability  to  replacemissing flux data in order to obtain reliable VOC sums. Ac-cording  to  our  findings  the  MDV  routine  was  outstandingwith regard to the minimization of the gap-filling error forboth  years  and  all  quantified  VOCs.  The  other  gap-fillingroutines,  which  performed  gap-filling  on  24 h  average  val-ues, introduced considerably larger uncertainties. The errorwhich was introduced by the application of the different fill-ing routines increased linearly with the number of data gaps.Although  average  VOC  fluxes  measured  during  the  winterperiod (complete snow coverage) were close to zero, thesewere highly variable and the filling of the winter period re-sulted in considerably higher uncertainties compared to theapplication of gap-filling during the measurement period.The  annual  patterns  of  the  overall  cumulative  fluxes  forthe  quantified  VOCs  showed  a  completely  different  behaviour  in  2009,  which  was  an  exceptional  year  due  tothe  occurrence  of  a  severe  hailstorm,  compared  to  2011.Methanol was the compound which, at 381.5 mg C m−2and449.9 mg  C m−2,  contributed  most  to  the  cumulative  VOCcarbon emissions in 2009 and 2011, respectively. In contrastto  methanol  emissions,  however,  considerable  amounts  ofmonoterpenes (−327.3 mg C m−2)were deposited onto themountain meadow during 2009 caused by a hailstorm. Otherquantified  VOCs  had  considerably  lower  influences  on  the annual patterns.
description: Biogeosciences Discussions, 10
description: ISSN:1810-6277
description: ISSN:1810-6285
Competition: Keep it Simple, Let Flooding Shine
Creators: name: Müller, Jan
name: Schaper, Anna-Brit
name: Jacob, Romain
name: Da Forno, Reto
Publisher: name: ETH Zurich
Year: 2019

description: This abstract presents our solutions to the EWSN 2019 Dependability Competition. We designed generic yet performant solutions by leveraging the flexibility of Baloo, a design framework tailored to synchronous transmissions. Instead of crafting subtle optimizations to match the Competition requirements, we used some well-known concepts and combined them efficiently to propose simple yet robust and efficient protocols. Keep it simple, let flooding shine!
description: Proceedings of the 2019 International Conference on Embedded Wireless Systems and Networks
description: ISBN:978-0-9949886-3-8
生物種の分布推定における標本情報等の活用
Creators: name: Ishihama, Fumiko
Publisher: name: figshare
Year: 2016
Subjects: subject: 50202 Conservation and Biodiversity
subject: FOS: Biological sciences
subject: 50101 Ecological Impacts of Climate Change
subject: FOS: Earth and related environmental sciences
subject: Ecology

description: 博物館の標本情報や市民調査による観察情報などに代表される、不在情報がない分布データは、在のみデータと総称される。GBIF（Global Biodiversity Information Facility）などの公開データベースの整備により、在のみデータは分布推定に広く用いられるようになり、その成果が保全生物学分野でも幅広く応用されている。しかし、在のみデータに基づく分布推定に際しては、不在情報がないことに起因する特有の注意点が生じる。特に注意が必要なのが、サンプリングバイアスの存在と、バイアスに対応した偽不在（pseudo-absence）の選び方、推定値の性質、推定精度の評価指標の値の解釈のしかたである。在のみデータに基づく分布推定を、保全対策に適切に活用するためには、これらの注意点とその対処法を十分に理解することが欠かせない。これらの注意点と対処法に関して、蓄積されつつある海外での報告事例を紹介する。
Presence-only data is a distribution data which lack absence information. Typical examples of presence-only data are herbarium specimen and chance observation data by civil survey. Presence-only data are widely used for distribution estimation due to establishment of open database such as GBIF (Global Biodiversity Information Facility), and obtained distribution predictions are used for various conservation applications. However, the lack of absence requires various specific cautions in estimating distribution based on presence-only data. Special attentions are needed about the existence of sampling biases, way of selecting pseudo-absence in correspondence to biases, the nature of estimated values, and interpretation of values of indices for evaluating estimation accuracies. For appropriate application of distribution estimations based on presence-only data in conservation measures, deep understanding about these cautions and techniques to cope with these problems are indispensable. I review accumulating international reports on these cautions and coping techniques.
Comparing operational performance of the Virtual Seismologist and FinDer for earthquake early warning
Creators: name: Massin, Frédérick
name: Boese, Maren
name: Cauzzi, Carlo V.
name: Clinton, John Francis
Publisher: name: ETH Zurich
Year: 2017

description: Geophysical Research Abstracts, 19
description: ISSN:1029-7006
description: ISSN:1607-7962
title: Reviewing achievability and ambition of Austria’s climate goal – a comparative analysis with German policy
Creators: name: Gam, Yeseul
Publisher: name: TU Wien
Year: 2020
Subjects: subject: climate change
subject: climate policy
subject: Austrian climate policy

description: The aggregate global efforts to deal with climate change are not yet sufficient to keep the temperature increase below 2 degrees, not to mention 1.5 degrees from the pre-industrial levels. The United Nations Framework Convention on Climate Change and the Paris Agreement builds the framework for global efforts, but national efforts supported by sub-national entities are essential to deal with the global challenge. To this end, this thesis will review whether Austria’s 2030 and 2040 goals are ambitious enough and could be achieved by comparing policy developments in Germany.First, the thesis will look at the global and the European climate policy framework, followed by Germany’s and Austria’s national framework, and then targets and recent updates of measures in both countries will be compared. There have been major updates in all layers in the recent years, with the submission or drafting of the 2030 climate plans by the EU member states and the EU’s Green Deal that set an ambitious goal of carbon neutrality by 2050.Second, this thesis will look at the current status of GHG emissions at the global, European and national levels, and analyze achievability of the 2030 goals and long-term goals (2040 for Austria, 2050 for Germany) of carbon neutrality in Germany and Austria. Third, the thesis will look at the very recent national political changes that have been taking place in Germany and Austria and at the awareness and ambition of major actors. To reflect upon the very recent changes, the thesis will consider how the unforeseen economic downturns linked to the COVID-19 crisis might affect ambitions. The thesis will also look at measures that are being discussed, such as carbon pricing, and measures that could be discussed, such as further investment in technologies and innovation.By comparing the climate policies and the status of Germany and Austria and their status of implementation, this thesis might be able to provide political impetus and direction for policymakers in Austria. Additionally, this comparison study could provide insights and inspiration for policymakers for other parts of the world.
Inhaled Long-acting Anticholinergics and Urinary Tract Infection in Individuals with COPD
Creators: name: Gershon, Andrea S.
name: Newman, Alice M.
name: Fischer, Hadas D.
name: Austin, Peter C.
name: Daneman, Nick
name: Bell, Chaim M.
name: Stephenson, Anne L.
name: Sudeep S. Gill
name: Vozoris, Nicholas T.
name: Rochon, Paula A.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: FOS: Biological sciences

description: Inhaled, long-acting anticholinergic medication (LAA), commonly used for moderate-to-severe chronic obstructive pulmonary disease (COPD), has been shown to decrease COPD hospitalizations, emergency department visits, and acute exacerbations but has also been associated with urinary tract infection (UTI) in a prior meta-analysis. The objective of this study was to verify if there was an association between LAA and UTI in older individuals with COPD. A population-based, real-world cohort study using health administrative data from Ontario, Canada was conducted. Incidence of UTI was compared between older people with physician-diagnosed COPD, who were new users of inhaled long-acting anticholinergics and new users of inhaled corticosteroids–a reference medication used in similar clinical settings that has no known association with UTI. Propensity score matching was used to minimize the effects of confounding. An overall association between LAA and various measures of UTI in older individuals was not found. However, in a priori defined stratified analyses, men newly initiated on LAA were 75% more likely to develop a UTI than men newly started on an inhaled corticosteroid (hazard ratio 1.75; 95% confidence interval 1.05–2.92). No significant association was seen in women. In conclusion, older men with COPD newly started on LAA are at increased risk of UTI. Men considering an inhaled LAA should be informed of this risk and, if they decide to take it, be provided with appropriate monitoring.
title: Recent trends in the development of assistance systems for biomedical research from a managerial perspective
Creators: name: Schneikart, Gerald
Publisher: name: TU Wien
Year: 2020
Subjects: subject: Biomedical Research
subject: Information Overload
subject: Laboratory Assistance
subject: Information System
subject: Systemic Risk

description: The major limiting factor in biomedical research is access to knowledge when and where it is needed, i.e. on the job. Every year, science produces vast amounts of novel insights, which a single human individual cannot grasp. Consequently, researchers are prone to develop a psychological state called information overload, which hampers creative thinking. In order to facilitate optimal innovation strategies, research organizations are advised to implement assistance systems, which provide opportunities for digital data management directly at the work bench in experimental laboratories. Within the scope of this thesis, different concepts of assistance systems for biomedical research were identified and profoundly reviewed. The thesis provides an overview of innovative solutions for specific problems, that may emerge during experimental work and the advantages they promise to research organizations. The individual reviews are completed with discussions on challenges and risks, which could be expected if the concepts were realized by strategic information technology-dependent initiatives. The research revealed several approaches designed for direct assistance of experimental researchers:-) automation of standardized, repetitive methodological routines,-) establishment of a ubiquitous computing environment to facilitate access to and storage of digital --) information at various locations in wet labs,-) integration of office and lab work into lab benches,-) guiding researchers through pipetting schemes, and-) helping researchers to remain focused on hands-on activities by applying augmented reality and voice assistance. Eventually, the emerging technological trend of virtual reality is included in the research because it indirectly assists researchers by effectively building tacit knowledge on practical lab work in a risk-free and cost-efficient manner, before entering real lab environments. Since none of the reviewed technological and software innovations are mainstream in research organizations yet, they were identified as disruptive technologies which still await an era of future laboratories, which demand their characteristics.
title: 12 - Entretien avec le vieil azmari Mulu’aläm Adägä : chant festif
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: chant

description: Chant festif.
Infarct delineation in patients with acute myocardial infarction using the tractographic propagation angle and late gadolinium enhancement
Creators: name: Mekkaoui, Choukri
name: Jackowski, Marcel P.
name: Stoeck, Christian
name: Kostis, William J.
name: Pereira, Fabricio
name: Kozerke, Sebastian
name: Sosnovik, David E.
Publisher: name: ETH Zurich
Year: 2015
Subjects: Fractional Anisotropy
Late Gadolinium Enhancement
Mean Diffusivity
Normal Myocardium
Helix Angle

description: Journal of Cardiovascular Magnetic Resonance, 17 (S1)
description: ISSN:1097-6647
description: ISSN:1532-429X
Hyperpolarized metabolic imaging of myocardial ischemia-reperfusion in a small-animal model at 9.4T
Creators: name: H-Ici, Darach O.
name: Wespi, Patrick
name: Busch, Julia
name: Wissmann, Lukas
name: Sigfridsson, Andreas
name: Weiss, Kilian
name: Messroghli, Daniel
name: Kozerke, Sebastian
Publisher: name: ETH Zurich
Year: 2015
Subjects: Pyruvate
Pyruvic Acid
Left Coronary Artery
Coronary Artery Occlusion
Swiss National Science Foundation

description: Journal of Cardiovascular Magnetic Resonance, 17 (S1)
description: ISSN:1097-6647
description: ISSN:1532-429X
Biodiversity for multifunctional grasslands: Equal productivity in high-diversity low-input and low-diversity high-input systems
Creators: name: Weigelt, Alexandra
name: Weisser, Wolfgang W.
name: Buchmann, Nina
name: Scherer-Lorenzen, Michael
Publisher: name: ETH Zurich
Year: 2009

description: Biogeosciences Discussions, 6
description: ISSN:1810-6277
description: ISSN:1810-6285
Harborough Rocks - Early Iron Age Settlement near Brassington, Derbyshire 2nd report.
Creators: name: Makepeace, G A
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 124, 64-68
description: Report on the finds, including pottery, flint, a jet or shale V-perforated button, a bone handle, and animal bones. Includes
Second order motion compensated spin-echo diffusion tensor imaging of the human heart
Creators: name: Stoeck, Christian
name: Deuster, von Deuster, Constantin
name: Genet, Martin
name: Atkinson, David
name: Kozerke, Sebastian
Publisher: name: ETH Zurich
Year: 2015

description: Journal of Cardiovascular Magnetic Resonance, 17 (S1)
description: ISSN:1097-6647
description: ISSN:1532-429X
Pottery from the Medieval iron smelting site at Stanley Grange, Derbyshire.
Creators: name: Beswick, Pauline
name: Challis, Keith C
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 124, 69-85
description: Rescue excavation recorded the remains of part of an extensive medieval iron smelting site. This paper reports on the medieval pottery from the excavation, which adds a further stratified collection of medieval ceramics to the overall assemblage from Derbyshire. The notional dating framework for the pottery may be compared with that from archaeomagnetic dates gained from the iron-smelting furnaces.
Medieval Pottery in Derbyshire: a review.
Creators: name: Cumberpatch, Chris G
name: Young, Janine
Publisher: name: Archaeology Data Service
Year: 2004

description: The Derbyshire Archaeological Journal, 124, 86-112
description: The article aims to establish an outline ceramic type series for northern and central Derbyshire, based on the evidence provided by sites discussed in the text. It also discusses the need for standardisation in terminology, the problems with identification of ware types from known production sites, and possible areas for future research. Includes