cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Civil Society and Human Rights as Part of the Neoliberal Narrative
Creators: name: Seixas, Eunice Castro
Publisher: name: Akademisk kvarter | Academic Quarter
Year: 2011

description: In Civil Society and Human Rights as Part of the Neoliberal Narrative: An Export to the Russian Federation by Eunice Castro Seixas we find a quite different global narrative. Its starting point is that civil society and human rights are global narratives, presumed universal narratives that are exported to the South and more recently to Eastern European borders, as part of the "global governance" ideology. Seixas suggests that human rights and civil society liberal narrative are being transformed and re-appropriated in today's Russian society, by the State, the Church and civil society organizations. Although there is not a full refusal of these liberal concepts by Russian human rights organizations, neither is there a clear alternative discourse.
description: Akademisk kvarter | Academic Quarter, Global Tales | Globale fortællinger, Vol. 2
How to use molecular clouds to study the propagation of cosmic rays in the Galaxy
Creators: name: Gabici, Stefano
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Observations of molecular clouds in the gamma ray domain provide us with a tool to study the distribution of cosmic rays in the Galaxy. This is because cosmic rays can penetrate molecular clouds, undergo hadronic interactions in the dense gas, and produce neutral pions that in turn decay into gamma rays. The detection of this radiation allows us to estimate the spectrum and intensity of cosmic rays at the cloud's position. Remarkably, this fact can be used to constrain the cosmic ray diffusion coefficient at specific locations in the Galaxy.
description: Invited talk, to appear on the proceedings of ICATPP Conference on Cosmic Rays for Particle and Astroparticle Physics, Villa Olmo, Como 7-8 October 2010
Discricionariedade Administrativa - Resumos das dissertações do mestrado (1986-1993)
Creators: name: Luiz Alberto Blanchet
Publisher: name: figshare
Year: 2020
Subjects: subject: 180103 Administrative Law
subject: FOS: Law

description: Discricionariedade, liberdade conferida pela lei ao administrador para, em caso de obscuridade, imprecisão ou lacuna normativa, suprir a finalidade especial do ato pertinente, é uma liberdade condicionada e não absoluta. Condiciona-se internamente, no processo de composição interior de sua essência, aos princípios que dão univocidade ao sistema jurídico-administrativo, e à finalidade (quando é delimitado o seu contorno e não o seu conteúdo), pelas exigências decorrentes da cOl~ugação da norma com o pressuposto fático (ambas figuras objetivas externas ao administrador). Pode, a discricionariedade, materializar-se em qualquer requisito (pressuposto ou elemento) do ato administrativo, com exceção apenas do sujeito. Para materializar-se no ato, a discricionariedade deve preexistir em estado latente na norma. E a sua presença na norma indica apenas a probabilidade e não a certeza de sua verificação em concreto, pois se o pressuposto fático encontra-se no grau máximo de relevância em relação à finalidade, não se consubstanciará discricionariedade, mas vinculação. Assim, a chamada "norma discricionária" é em verdade, "norma potencialmente discricionária". Sendo a norma e o motivo, ambos objetivos, e assim, existentes fora da mente do administrador, podem e devem ser conhecidos objetivamente por ele e não criados subjetivamente. Em conseqüência, a avaliação de ambos submete-se à análise do Poder Judiciário. Já a solução (produto da criatividade subjetiva do administrador) constitui o terreno da discricionariedade, d
Localization of TGF-beta signaling intermediates Smad2, 3, 4, and 7 in developing and mature human and mouse kidney
Creators: name: Banas, Miriam C.
name: Parks, W. Tony
name: Hudkins, Kelly L.
name: Banas, Bernhard
name: Holdren, Matthew
name: Iyoda, Masayuki
name: Wietecha, Tomasz A.
name: Kowalewska, Jolanta
name: Liu, Gang
name: Alpers, Charles E.
Publisher: name: Universität Regensburg
Year: 2007
Subjects: subject: Smads; transforming growth factor-beta;renal pathology; kidney development; cell signaling; immunohistochemistry
subject: 610 Medizin

description: Smad proteins are signaling intermediates of the TGF-beta superfamily and are involved in a range of biological activities including development and immune responses. We studied the expression of TGF-beta-receptor activated Smads (Smad2 and Smad3), the common partner Smad (Smad4), an inhibitory Smad (Smad7), and the activated (phosphorylated) Smad2 (pSmad2) in developing and adult kidneys of humans and mice. These studies demonstrate associated expression of these Smads in multiple renal cell types in all developmental stages and in mature non-diseased kidneys. Smad expression is in general most widespread at the earliest stages of nephron development and diminishes as components of the nephrons become more differentiated. Paucity of Smad expression in mesangial cells in contrast to widespread expression of these Smads in glomerular visceral epithelial cells in both developing and mature kidneys was remarkable. Divergent and less extensive expression of Smad4, compared with other Smad proteins, was also demonstrated in tubules of human kidneys. Based on the observed expression patterns, these findings demonstrate, for the first time, expression of the TGF-beta-receptor-activated Smad2 and Smad3, the common mediator Smad4, and the inhibitory Smad7 in the developing human fetal kidney, extending observations previously made in rodent systems to humans.
Klimaproblematikken som global fortælling
Creators: name: Eskjær, Mikkel Fugl
Publisher: name: Akademisk kvarter | Academic Quarter
Year: 2011

description: Mikkel Eskjær presents us with three different narratives about the climate issue in The climate problematic as a global narrative: Medialization of a late modern risk: a) different sociological scenarios that give us an understanding of the causes and consequences of climate change, b) the media's narratives, their character, and content, and c) popular culture representations in the form of disaster narratives about the climate. Those narratives are helping to create the meanings that climate issues get at a global level.
description: Akademisk kvarter | Academic Quarter, Global Tales | Globale fortællinger, Vol. 2
Sehet! - Wen? - den Bräutigam!: Matthew's Jesus as Bridegroom in the Matthäuspassion of J.S Bach
Creators: name: Jankowski, Jarek
Publisher: name: University of Notre Dame
Year: 2023

description: [Undergraduate Library Research Award](http://http://library.nd.edu/ulra/) Honorable Mention, 20000-40000 Level Course
Mikrokredittens globale fortælling og dens etiske problemstillinger
Creators: name: Jensen, Thessa
Publisher: name: Akademisk kvarter | Academic Quarter
Year: 2011

description: The global narrative of microloan and its ethical issues by Thessa Jensenhighlights microcredit's chronological development from its origins in Bangladesh to its potentials today in the era of an Internet-based economy. In this narrative there is a conflict between the poor borrowers (the original recipients) and the development of microcredit institutions that will only work with market economy logics: profitability and growth. Jensen analyzes the ethical challenges that this conflict provides and tries to find an answer to them involving the ideas of Løgstrup and Levinas.
description: Akademisk kvarter | Academic Quarter, Global Tales | Globale fortællinger, Vol. 2
Bøgerne om alt – fortalt af mange
Creators: name: Hansen, Kim Toft
Publisher: name: Akademisk kvarter | Academic Quarter
Year: 2011

description: In Books about the lot - told by a lot. Lene Andersen's global existentialism, Kim Toft Hansen presents and analyzes Baade og, a comprehensive and distinctive work in five volumes by Lene Andersen. You can place this intellectual performance as a kind of map in which different genres and sciences are mixed. An especially interesting theme in this issue of Academic Quarter is Lene Andersen's ideas of a global existentialism containing a critique of religion, science and business: scientific arrogance, religious stupidity and commercial cynicism. Simultaneously there is an appeal to those cultural and economic systems to work as centripetal forces and to contribute to the common good acting positively e.g. promoting prosperity, education, formation, community and awareness about responsibilities.
description: Akademisk kvarter | Academic Quarter, Global Tales | Globale fortællinger, Vol. 2
Exchange correlation vector potentials and vorticity-dependent exchange-correlation energy densities for two-dimensional systems
Creators: name: Wensauer, Andreas
name: Rössler, Ulrich
Publisher: name: Universität Regensburg
Year: 2004
Subjects: subject: 530 Physik

description: We present an approach to calculating the scalar and vector exchange-correlation potentials from current-carrying ground states of two-dimensional quantum dots. From these exchange-correlation potentials we derive exchange-correlation energy densities and examine their vorticity (or current) dependence. Compared with parametrizations of current-induced effects in the literature we find an increased significance of corrections due to paramagnetic current densities.
Home turf : re-earthing family narrative
Creators: name: Jonsson, Tomas
Publisher: name: University of British Columbia
Year: 2018

description: At the same time as my father’s deteriorating health, the culmination of a long process of development in the neighbourhood my family had lived in for 40 years occurred. Through periodic transfers between home and hospital, we witnessed the uprooting of trees, the construction of roadways and subdividing of properties, including our own. Our house was soon marked for sale and redevelopment, and our affects moved to a new location following his passing. These materials, an archive of ephemera, photos and letters that tell the story of our family from their journey from Denmark and eventual settling in Canada, now sit in cardboard boxes and Tupperware containers. Using these personal ‘affects’, I am engaged in a long-term performative engagement, using them as a lens to interrogate larger conditions urban development, migration, colonial histories, logics in which our history is implicated. These are teased out of the contents of the material and texts in my family’s collection. Familial objects, gathered from my mother’s archive are mailed to our former address. As this house no longer exists, the materials are redirected, wearing the imprinted marks of the journey.
Complexity analysis of Klein-Gordon single-particle systems
Creators: name: Manzano, Daniel
name: López-Rosa, Sheila
name: Sánchez-Dehesa, Jesús
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The Fisher-Shannon complexity is used to quantitatively estimate the contribution of relativistic effects to on the internal disorder of Klein-Gordon single-particle Coulomb systems which is manifest in the rich variety of three-dimensional geometries of its corresponding quantum-mechanical probability density. It is observed that, contrary to the non-relativistic case, the Fisher-Shannon complexity of these relativistic systems does depend on the potential strength (nuclear charge). This is numerically illustrated for pionic atoms. Moreover, its variation with the quantum numbers (n, l, m) is analysed in various ground and excited states. It is found that the relativistic effects enhance when n and/or l are decreasing.
description: 4 pages, 3 figures, Accepted in EPL (Europhysics Letters)
Globaliseringen hos Ernst Jünger
Creators: name: Schlosser, Jan T.
Publisher: name: Akademisk kvarter | Academic Quarter
Year: 2011

description: In The globalization in Ernst Jünger. From World War to World State, Jan Schlosser follows the German writer's understanding of global phenomena and the development of global narratives in his writings. In the early works of Jünger he reflected on the modern technology that was developed in connection with World War I. In this period he had the controversial view that there are people who master these technologies. After Germany's defeat Jünger was a spokesman for a world state and already questioned the national state, which he considered the source of mass extinction. Schlosser shows that Jünger continued to be a supporter of the vision of a world state, but that in his later days he developed a critical narrative of globalization for different reasons. One reason was the ecological imbalance created by human greed for energy. Another reason was globalization's cultural homogenization with the following loss of cultural diversity.
description: Akademisk kvarter | Academic Quarter, Global Tales | Globale fortællinger, Vol. 2
Reverse diastolic intrarenal flow due to calcineurin inhibitor (CNI) toxicity
Creators: name: Böger, Carsten A.
name: Rümmele, Petra
name: Mihatsch, Michael J.
name: Banas, Bernhard
name: Krämer, Bernhard K.
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Calcineurin inhibitor toxicity; Doppler sonography; histology; immunosuppression; kidney transplantation; renal failure
subject: 610 Medizin

description: Renal calcineurin inhibitor (CNI) toxicity is a frequent side effect of immunosuppression with CNIs in solid organ transplantation, leading to acute and chronic renal failure. Acute CNI toxicity is due to vasoconstriction of the vasa afferens and efferens and vacuolization of smooth muscle cells with medial hyalinosis, leading to vessel lumen narrowing. Our case had an acute renal failure 8 months after deceased donor kidney transplantation under treatment with tacrolimus, sirolimus and prednisolone. In Doppler sonography, we observed reverse diastolic intrarenal blood flow, reflecting intense vessel narrowing. There were histological signs of acute CNI toxicity. Within days of reducing the tacrolimus trough level, renal function improved markedly and Doppler sonography showed orthograde intrarenal blood flow. This is the first case of functional, Doppler sonographic evidence for CNI-induced, rapidly reversible narrowing of intrarenal vessels. This case illustrates the potential role of tacrolimus and sirolimus dosing in combination therapy to produce severe intrarenal vasoconstriction.
Geometric Spin Hall Effect of Light at Polarizing Interfaces
Creators: name: Korger, Jan
name: Aiello, Andrea
name: Gabriel, Christian
name: Banzer, Peter
name: Kolb, Tobias
name: Marquardt, Christoph
name: Leuchs, Gerd
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The geometric Spin Hall Effect of Light (geometric SHEL) amounts to a polarization-dependent positional shift when a light beam is observed from a reference frame tilted with respect to its direction of propagation. Motivated by this intriguing phenomenon, the energy density of the light beam is decomposed into its Cartesian components in the tilted reference frame. This illustrates the occurrence of the characteristic shift and the significance of the effective response function of the detector. We introduce the concept of a tilted polarizing interface and provide a scheme for its experimental implementation. A light beam passing through such an interface undergoes a shift resembling the original geometric SHEL in a tilted reference frame. This displacement is generated at the polarizer and its occurrence does not depend on the properties of the detection system. We give explicit results for this novel type of geometric SHEL and show that at grazing incidence this effect amounts to a displacement of multiple wavelengths, a shift larger than the one introduced by Goos-Hänchen and Imbert-Fedorov effects.
description: 6 pages, 4 figures
Electronic structure of pristine and K-doped solid picene: Non-rigid-band change and its implication for electron-intramolecular-vibration interaction
Creators: name: Okazaki, H.
name: Wakita, T.
name: Muro, T.
name: Kaji, Y.
name: Lee, X.
name: Mitamura, H.
name: Kawasaki, N.
name: Kubozono, Y.
name: Yamanari, Y.
name: Kambe, T.
name: Kato, T.
name: Hirai, M.
name: Muraoka, Y.
name: Yokoya, T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We use photoemission spectroscopy to study electronic structures of pristine and K-doped solid picene. The valence band spectrum of pristine picene consists of three main features with no state at the Fermi level (EF), while that of K-doped picene has three structures similar to those of pristine picene with new states near EF, consistent with the semiconductor-metal transition. The K-induced change cannot be explained with a simple rigid-band model of pristine picene, but can be interpreted by molecular orbital calculations considering electron-intramolecular-vibration interaction. Excellent agreement of the K-doped spectrum with the calculations points to importance of electron-intramolecular-vibration interaction in K-doped picene.
description: This article is accepted by Physical Review B
Globale fortællinger i den skandinaviske krimi
Creators: name: Agger, Gunhild
Publisher: name: Akademisk kvarter | Academic Quarter
Year: 2011

description: Gunhild Agger's Global Tales in Scandinavian Crime Fiction - Myths, History, Christianity and Moral Philosophy presents us with some of the reasons behind the Scandinavian crime fiction success at home and globally. One of the best known reasons is that crime fictions contain a critique of liberalism and capitalism that show the downside of this ideology and this system. However, Agger claims that there are other important reasons that can help explain the worldwide success of Scandinavian crime fiction: the skillful use of common global narratives such as myths, history, Christianity and moral philosophy. For example the mythical dimension allows a deeper plot dimension, the historical dimension uses a common understanding of the periods in European history, which is a partially known at a global level, and a Christian perspective helps with a common cultural code, namely the Bible and its narratives.
description: Akademisk kvarter | Academic Quarter, Global Tales | Globale fortællinger, Vol. 2
The Meek Inherit the Earth
Creators: name: Stone, James D.
Publisher: name: Akademisk kvarter | Academic Quarter
Year: 2011

description: In The Meek Inherit the Earth: Celebrating the End of American Power in Mars Attacks!, James Stone suggests that Mars Attacks, besides celebrating the aesthetics of alien invasion films, differs from other alien invasion films in the sense that while most Hollywood movies belonging to this group demonstrate U.S. strength and ingenuity, Mars Attacks! goes against the grain by refusing the general pro-American tone and foregrounding America's weaknesses; the film mischievously hints that the fall of the U.S. would be no tragedy, but an occasion for celebration.
description: Akademisk kvarter | Academic Quarter, Global Tales | Globale fortællinger, Vol. 2
Transport and elementary excitations of a Luttinger liquid (letter to the editor)
Creators: name: Cuniberti, Gianaurelio
name: Sassetti, Maura
name: Kramer, Bernhard
Publisher: name: Universität Regensburg
Year: 1996
Subjects: subject: 530 Physik

description: The low-temperature AC conductance of a one-dimensional electron system with a strong interaction of finite range is calculated by using linear response theory. The conductance factorizes into parts which depend on the internal properties of the system, and the external probe. For short-range interaction, the result resembles that for non-interacting electrons, but with the zero-frequency limit and the Fermi velocity renormalized by the interaction strength. For strong and long-range interaction, the conductance shows a peak that is related to charge-wave excitations. In this limit, the AC conductance can be simulated by a quantum capacitance and a quantum inductance.
Magnetic Miniband Structure and Quantum Oscillations in Lateral Semiconductor Superlattices
Creators: name: Langenbuch, Michael
name: Suhrke, Michael
name: Rössler, Ulrich
Publisher: name: Universität Regensburg
Year: 2003
Subjects: subject: 530 Physik

description: We present fully quantum-mechanical magnetotransport calculations for short-period lateral superlattices with one-dimensional electrostatic modulation. A non-perturbative treatment of both magnetic field and modulation potential proves to be necessary to reproduce novel quantum oscillations in the magnetoresistance found in recent experiments in the resistance component parallel to the modulation potential. In addition, we predict oscillations of opposite phase in the resistance component perpendicular to the modulation not yet observed experimentally. We show that the new oscillations originate from the magnetic miniband structure in the regime of overlapping minibands.
Non-orientable quasi-trees for the Bollobas-Riordan polynomial
Creators: name: Vignes-Tourneret, Fabien
Publisher: name: arXiv
Year: 2011
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C10, 05C31, 57M27

description: We extend the quasi-tree expansion of A. Champanerkar, I. Kofman, and N. Stoltzfus to not necessarily orientable ribbon graphs. We study the duality properties of the Bollobas-Riordan polynomial in terms of this expansion. As a corollary, we get a "connected state" expansion of the Kauffman bracket of virtual link diagrams. Our proofs use extensively the partial duality of S. Chmutov.
description: 31 pages, 11 figures
Stark effect on diamagnetic Rydberg states
Creators: name: Richter, Klaus
name: Wintgen, Dieter
name: Briggs, J.
Publisher: name: Universität Regensburg
Year: 1987
Subjects: subject: 530 Physik

description: The Stark effect on diamagnetic Rydberg states of hydrogen is investigated. In the perturbative regime, re-ordering of levels within a hydrogenic n manifold leads to level repulsion when the ratio of field strengths is varied. When the fields become strong enough very narrow avoided crossings between levels from different n manifolds appear. In addition the authors study the Stark effect on recently observed quasiLandau structure in the irregular part of the spectrum.
TGF-beta1 induces COX-2 expression and PGE2 synthesis through MAPK and PI3K pathways in human mesangial cells
Creators: name: Rodríguez-Barbero, A.
name: Dorado, F.
name: Velasco, S.
name: Pandiella, A.
name: Banas, B.
name: López-Novoa, J. M.
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: transforming growth factor-1; cyclooxygenase; prostaglandin-E2; mesangial cells; mitogen-activated protein kinase; phosphatidylinositol 3 kinase
subject: 610 Medizin

description: Transforming growth factor-beta1 (TGF-beta1) plays a fundamental role in the progression of renal diseases. Accumulating evidence has suggested that eicosanoids derived from cyclooxygenase-2 (COX-2) participate in a number of pathological processes in immune-mediated renal diseases. Mesangial cells (MC) play a major role in physiological and pathophysiological renal processes. MC express receptors for TGF-beta1, and COX-2 expression can be induced in MC. However, to date, there are no published data on the possible role of TGF-beta1 in COX-2 expression in human mesangial cells (HMC). We designed studies to determine (1) whether TGF-beta1 stimulates COX-2 expression in primary HMC, (2) whether mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K) cascades are involved in TGF-beta1-induced COX-2 expression, and (3) whether prostaglandin (PG)E2 synthesis is affected by TGF-beta1 and MAP kinases and PI3K activation. Studies were performed in primary cultures of HMC and in an immortalized line of HMC. TGF-beta1 induces COX-2 promoter activity and COX-2 mRNA and protein expression in HMC. COX-2 induction is accompanied by increased PGE2 synthesis. Extracellular signal-regulated kinase (ERK)1/2, p38 MAPK, and PI3K pathway inhibition blunted TGF-beta1-induced COX-2 overexpression. We demonstrate that TGF-beta1 regulates COX-2 expression in HMC through the activation of ERK1/2, p38 MAPK, and PI3K. These results can help to elucidate the molecular mechanisms underlying the regulation of COX-2 and open up specific strategies for the treatment of glomerular disease.
Faraday rotation and primordial magnetic field constraints on Ultraviolet Lorentz violation with spacetime torsion
Creators: name: de Andrade, L C Garcia
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Recently Kahniashivili et al (2006) presented a unified treatment for ultraviolet Lorentz violation (LV) testing through electromagnetic wave propagation in magnetised plasmas, based on dispersion and rotation measured data. Based on the fact discovered recently by Kostelecky et al (2008), that LV may place constraints on spacetime torsion, in this paper it is shown that on the limit of very low frequency torsion waves, it is possible to constraint torsion from Faraday rotation and CMB on a similar fashion as Minkowski spacetime plus torsion. Here the Maxwells modified equations are obtained by a perturbative method introduced by de Sabbata and Gasperini (1981). Torsion is constraint to $Q_{CMB}\approx{10^{-18}GeV}$ which is not so stringent as the $10^{-31}GeV$ obtained by Kostelecky et al. However, Gamma Ray Bursts (GBRs) may lead to the more string value obtined by Kostelecky et al. Another interesting constraint on torsion is shown to be placed by galactic dynamo seed magnetic fields. For torsion effects be compatible with the galactic dynamo seeds one obtains a torsion constraint of $10^{-33}GeV$ which is two orders of magnitude more stringent that the above Kostelecky et al limit.
description: Departamento de fisica teorica-Universidade do Estado do Rio de Janeiro-UERJ
Shaping of the T cell repertoire by self and foreign antigens
Creators: name: Tsai, Kevin
Publisher: name: University of British Columbia
Year: 2021

description: T cells are an indispensable component of the immune system. Any perturbation in T cell function may have severe consequences such as immune deficiency, autoimmunity or development of malignancies. T cell receptors and the signals transduced by them are critical for many aspects of T cell biology. A diverse yet tolerant TCR repertoire is essential for the proper functioning of the immune system. Herein, we investigated several factors that regulate T cell immune responses, autoimmunity and the TCR repertoire. We investigated whether co-delivery of autoantigen insulin along the natural killer T cell antigen αGalCer within novel liposomes could prevent T1D in non-obese diabetic mice. We found that subcutaneous injection of such liposomes could potently stimulate NKT cells to activate other immune cell types. Further, their subcutaneous administration reduced the frequency of islet-reactive T cells and conferred protection against diabetes. These experiments suggest that using liposomes to co-deliver autoantigens along with αGalCer may prove to be a valuable for the prevention of autoimmune diseases. Next, we examined whether the expression of two types of TCRs by individual CD8 T cells could contribute to autoreactivity and autoimmunity. We compared the reactivity against the model autoantigen OVA between CD8 T cells capable of expressing two types of TCRs (bi-allelic, TCRα⁺/⁺) versus those restricted to a single TCR (mono-allelic, TCRα+/-). Bi-allelic CD8 T cells exhibited increased proliferative capacity and autoreactivity relative to mono-allelic CD8 T cells. Altogether, our results suggest that dual TCR-expressing CD8 T cells evade tolerance and participate in the pathogenesis of autoimmunity. Lastly, we studied the role of MUC2 mucin in regulating CD8 T cell tolerance against oral antigens. Wild type and MUC2-deficient (Muc2-/-) mice were orally gavaged with ovalbumin (OVA) to examine the impact of dietary antigens on CD8 T cells. We found that oral administration resulted in rapid systemic dissemination of OVA in the blood and tissues of Muc2-/- mice, and culminated in the deletion of OVA-specific thymocytes. Consequently, our findings suggest that MUC2-deficiency results the shaping the TCR repertoire of developing thymocytes by intestinal luminal antigens.
Study of Auto-igniting Spray Flame in Vitiated Swirling Hot Coflow using flamelet generated model
Creators: name: Alam, Zafar
name: Bhatia, Bharat
name: De, Ashoke
Publisher: name: arXiv
Year: 2025
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Swirl-stabilized auto-igniting spray flames are essential for designing efficient and clean combustion systems. The present study performs large eddy simulations (LES) of the dilute auto-igniting methanol flame in a vitiated, hot coflow of varying swirl intensities. The six-dimensional Flamelet Generated Manifold (FGM) technique is used to solve the reactive flow accurately and economically. The swirl numbers (SN), i.e. 0.2, 0.6, 1.0, and 1.4, are used to assess their effect on auto-ignition and flame stability. At lower to moderate swirl numbers (SN =0.2, 0.6), the increase in swirl is found to increase the lift-off height. Beyond the critical swirl number (SN=0.6), the lift-off height drops. Also, the time-averaged flame structure transitions from a tubular-like flame into a uniformly distributed combustion region at these high swirl numbers. It also results in a more compact flame for the higher swirl numbers. These effects on flame dynamics are analyzed in detail using the mean gas-phase flow field distribution, particle statistics, and proper orthogonal decomposition (POD).
Therapie und Prophylaxe rezidivierender Harnwegsinfekte
Creators: name: Banas, Bernhard
name: Krämer, Bernhard K.
Publisher: name: Universität Regensburg
Year: 2005
Subjects: subject: Urinary tract infection; Antibiotic therapy; Antibiotic prophylaxis; Vaccine Rezidivierender Harnwegsinfekt; Antibiotika therapie; Antibiotika prophylaxe; Impfung
subject: 610 Medizin

description: Recurrent urinary tract infections are typical diseases of sexually active young women. Only elder women show significant rates of underlying, mostly urological diseases. Besides behavioral changes long-term antimicrobial therapy is still the mainstay of both prophylaxis and therapy. This report provides information on the etiology for recurrent urinary tract infections. Strategies for prevention are illustrated. The actual significances of organic remedies and antibiotics respectively are discussed; ineffective therapies are identified. Furthermore an outlook is given on promising novel therapeutics, i.e. vaccines which are already tested in clinical trials.
 Rezidivierende Harnwegsinfekte sind typische Erkrankungen sexuell aktiver, junger Frauen. Nur bei älteren Frauen finden sich gehäuft zumeist urologische Grunderkrankungen. Neben Veränderungen der Lebensgewohnheiten ist die antibiotische Langzeitbehandlung bis heute Eckpfeiler der Prophylaxe und Therapie. Der vorliegende Beitrag erläutert kurz die Pathogenese und Risikofaktoren von rezidivierenden Harnwegsinfekten, so wie Strategien zu deren Prävention. Der aktuelle Stellenwert von pflanzlichen Wirkstoffen und Antibiotika wird diskutiert, unwirksame Therapieansätze werden er klärt. Schließlich weist ein Ausblick auf die in Entwicklung be findlichen und z.T. schon in klinischen Studien angewandten Impfstoffe als vielversprechende, zukünftige Therapieoption hin.
Nondiffracting beams for vortex tomography
Creators: name: Rehacek, J.
name: Hradil, Z.
name: Bouchal, Z.
name: Klimov, A. B.
name: Rigas, I.
name: Sanchez-Soto, L. L.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a reconstruction of vortex beams based on the implementation of quadratic transformations in the orbital angular momentum. The information is encoded in a superposition of Bessel-like nondiffracting beams. The measurement of the angular probability distribution at different positions allows for the reconstruction of the Wigner function.
description: 3 pages. 2 eps figures. To appear in Optics Letters
Internet of Things: Considerations and Recommendations for Internet-Based Voting Equipment
Creators: name: Harris, Rachael
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: Computer System Security

description: In this thought-provoking article featured in the Heinz Journal, the author explores the intricate landscape of secure Internet Voting (IV) within the Internet of Things (IoT), providing a groundbreaking examination of Type 1 online voting devices. Unveiling vulnerabilities that have received scant attention, the paper delves into the complex web of threats, including DNS vulnerabilities, ransomware risks, and insecure default settings. This innovative contribution offers fresh perspectives on a notably under-covered topic, making significant strides in the understanding of potential implications for democratic processes. The article's rich insights and comprehensive approach underscore its significance in the broader discourse on technology, policy, and democracy. A must-read for those seeking a deeper understanding of the evolving intersection between technology and the democratic voting process.
Chiral model for $\bar{K}N$ interactions and its pole content
Creators: name: Cieply, A.
name: Smejkal, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We use chirally motivated effective meson-baryon potentials to describe the low energy $\bar{K}N$ data including the characteristics of kaonic hydrogen. Our results are examined in comparison with other approaches based on the unitarity and dispersion relation for the inverse of the T-matrix. We demonstrate that the movements of the poles generated by the model upon varying the model parameters can serve as a tool to get additional insights on the dynamics of the strongly coupled $πΣ$-$\bar{K}N$ system.
description: contribution to the Chiral10 workshop, Valencia (Spain), June 21-24, 2010
Clinical management of large adrenal cystic lesions
Creators: name: Schmid, Holger
name: Mussack, Thomas
name: Wörnle, Markus
name: Pietrzyk, Miriam C.
name: Banas, Bernhard
Publisher: name: Universität Regensburg
Year: 2005
Subjects: subject: Adrenalectomy; Adrenal carcinoma; Adrenal cyst; Adrenal endocrine dysfunction; Adrenal gland; Pheochromocytoma
subject: 610 Medizin

description: The widespread use of ultrasonography and computed tomography has resulted in an increased diagnosis of large sized adrenal cysts with diameters of more than 5 cm. Most of these adrenal cystic lesions are clinically silent and are therefore often diagnosed incidentally. Since up to 7% of adrenal cysts are malignant, a careful hormonal, morpho-functional and instrumental evaluation is mandatory. In particular, functioning adrenal carcinomas or pheochromocytomas have to be ruled out. Fine needle aspiration cytology as well as examination of a punch biopsy specimen of the cystic wall are of limited value, as there is considerable overlap in cytologic and histologic features of benign and malignant adrenal cystic lesions. Immediate surgical excision is indicated in the presence of symptoms, suspicion of malignancy, increase in the size or detection of a functioning adrenal cyst. En bloc adrenalectomy, preferably by a laparoscopic approach, has become the treatment of choice.
Address of the Roman Catholics to their fellow citizens, of the City and State of New York.
Creators: name: Not Assigned
Publisher: name: University of Notre Dame
Year: 2023

description:
 Objecting to the common law system, adopted by the New York state legislature, under which religious education of any type would be prohibited in the public schools.
 Signed by John Hughes and others.
 The above address, was unanimously adopted at a general meeting of the Catholics of the city of New-York, in the school room of St. James' Church, August 10th, 1840, having been submitted by John Hughes, Bishop of Basileopolis, coadjutor and administrator of the Diocese of New-York [and eight others], committee.--Page 14.
RANTES gene polymorphisms predict all-cause and cardiac mortality in type 2 diabetes mellitus hemodialysis patients
Creators: name: Böger, Carsten A.
name: Fischereder, Michael
name: Deinzer, Martina
name: Aslanidis, Charalampos
name: Schmitz, Gerd
name: Stubanus, Mike
name: Banas, Bernhard
name: Krüger, Bernd
name: Riegger, Günter A. J.
name: Krämer, Bernhard K.
Publisher: name: Universität Regensburg
Year: 2005
Subjects: subject: Genetics of vascular disorders; Atherosclerosis; Dialysis; Adult diabetes; Cardiovascular risk
subject: 610 Medizin

description: INTRODUCTION: Patients with type 2 diabetes (DM2) and end stage renal disease (ESRD) have a dismal survival prognosis, mainly due to cardiovascular events. There is sparse data on genetic predictors. Chemokines and their receptors are important in regulating leukocyte influx and activation in atherosclerosis, and functional polymorphisms in the respective genes are associated with cardiovascular disease risk. METHODS: We enrolled 225 prevalent Caucasian DM2 patients receiving maintenance hemodialysis in 30 centres in Southern Germany (time from dialysis initiation <2.0 years) from August 1999 to January 2000 for prospective study until December 2003. The CX3CR1 T280M, and MCP-1 -2518 and RANTES -403 and -28 promoter and intronic In1.1T/C polymorphisms were assessed by real-time PCR. Primary end point was all-cause mortality (ACM). RESULTS: Patients carrying the RANTES -403A or In1.1C allele had a significantly higher ACM risk (multivariate hazard ratio for -403A, dominant model=1.81 [95% CI: 1.22-2.67], p=0.003), mainly due to cardiac events. Similar data were obtained by haplotype analysis. The other SNPs showed no effect on survival. DISCUSSION: In DM2 patients with ESRD, ACM due to cardiac events is associated with RANTES gene variants that are known to alter the expression of this chemokine important in atherosclerosis. Further study of the role of chemokine and chemokine receptor gene variation in determining vascular end points is needed.
Source estimation and uncertainty quantification for wave-equation based seismic imaging and inversion
Creators: name: Fang, Zhilong
Publisher: name: University of British Columbia
Year: 2018

description: In modern seismic exploration, wave-equation-based inversion and imaging approaches are widely employed for their potential of creating high-resolution subsurface images from seismic data by using the wave equation to describe the underlying physical model of wave propagation. Despite their successful practical applications, some key issues remain unsolved, including local minima, unknown sources, and the largely missing uncertainty analyses for the inversion. This thesis aims to address the following two aspects: to perform the inversion without prior knowledge of sources, and to quantify uncertainties in the inversion. The unknown source can hinder the success of wave-equation-based approaches. A simple time shift in the source can lead to misplaced reflectors in linearized inversions or large disturbances in nonlinear problems. Unfortunately, accurate sources are typically unknown in real problems. The first major contribution of this thesis is, given the fact that the wave equation linearly depends on the sources, I have proposed on-the-fly source estimation techniques for the following wave-equation-based approaches: (1) time-domain sparsity-promoting least-squares reverse-time migration; and (2) wavefield-reconstruction inversion. Considering the linear dependence of the wave equation on the sources, I project out the sources by solving a linear least-squares problem, which enables us to conduct successful wave-equation-based inversions without prior knowledge of the sources. Wave-equation-based approaches also produce uncertainties in the resulting velocity model due to the noisy data, which would influence the subsequent exploration and financial decisions. The difficulties related to practical uncertainty quantification lie in: (1) expensive computation related to wave-equation solves, and (2) the nonlinear parameter-to-data map. The second major contribution of this thesis is the proposal of a computationally feasible Bayesian framework to analyze uncertainties in the resulting velocity models. Through relaxing the wave-equation constraints, I obtain a less nonlinear parameter-to-data map and a posterior distribution that can be adequately approximated by a Gaussian distribution. I derive an implicit formulation to construct the covariance matrix of the Gaussian distribution, which allows us to sample the Gaussian distribution in a computationally efficient manner. I demonstrate that the proposed Bayesian framework can provide adequately accurate uncertainty analyses for intermediate to large-scale problems with an acceptable computational cost.
The extreme physical properties of the CoRoT-7b super-Earth
Creators: name: Léger, A.
name: Grasset, O.
name: Fegley, B.
name: Codron, F.
name: Albarede, A. F.
name: Barge, P.
name: Barnes, R.
name: Cance, P.
name: Carpy, S.
name: Catalano, F.
name: Cavarroc, C.
name: Demangeon, O.
name: Ferraz-Mello, S.
name: Gabor, P.
name: Griessmeier, J. -M.
name: Leibacher, J.
name: Libourel, G.
name: Maurin, A-S.
name: Raymond, S. N.
name: Rouan, D.
name: Samuel, B.
name: Schaefer, L.
name: Schneider, J.
name: Schuller, P. A.
name: Selsis, F.
name: Sotin, C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The search for rocky exoplanets plays an important role in our quest for extra-terrestrial life. Here, we discuss the extreme physical properties possible for the first characterized rocky super-Earth, CoRoT-7b (R_pl = 1.58 \pm 0.10 R_Earth, Mpl = 6.9 \pm 1.2 M_Earth). It is extremely close to its star (a = 0.0171 AU = 4.48 R_st), with its spin and orbital rotation likely synchronized. The comparison of its location in the (Mpl, Rpl) plane with the predictions of planetary models for different compositions points to an Earth-like composition, even if the error bars of the measured quantities and the partial degeneracy of the models prevent a definitive conclusion. The proximity to its star provides an additional constraint on the model. It implies a high extreme-UV flux and particle wind, and the corresponding efficient erosion of the planetary atmosphere especially for volatile species including water. Consequently, we make the working hypothesis that the planet is rocky with no volatiles in its atmosphere, and derive the physical properties that result. As a consequence, the atmosphere is made of rocky vapours with a very low pressure (P \leq 1.5 Pa), no cloud can be sustained, and no thermalisation of the planetary is expected. The dayside is very hot (2474 \leq 71 K at the sub-stellar point) while the nightside is very cold (50 to 75 K). The sub-stellar point is as hot as the tungsten filament of an incandescent bulb, resulting in the melting and distillation of silicate rocks and the formation of a lava ocean. These possible features of CoRoT-7b could be common to many small and hot planets, including the recently discovered Kepler-10b. They define a new class of objects that we propose to name "Lava-ocean planets".
BK virus associated nephropathy in native kidneys of a heart allograft recipient
Creators: name: Schmid, Holger
name: Burg, Michael
name: Kretzler, Matthias
name: Banas, Bernhard
name: Gröne, Hermann-Josef
name: Kliem, Volker
Publisher: name: Universität Regensburg
Year: 2005
Subjects: subject: 610 Medizin

description: Polyomavirus-mediated nephropathy is an increasingly recognized complication in renal transplant recipients, but data on the status of viral activity in the native kidneys of non-renal solid organ recipients are limited. Thirteen native kidney biopsies of heart transplant recipients with significant renal impairment were evaluated for the evidence of polyomavirus reactivation by immunohistochemistry and PCR. One case of BK virus-mediated nephropathy in a cardiac transplant recipient exposed to high levels of immunosuppressive drugs was identified. Clinical and histopathological findings of this patient progressing to terminal renal failure are discussed in detail. In conclusion, polyomavirus reactivation in native kidneys of heart transplant recipients can cause significant renal impairment and should be considered in the differential diagnosis in this patient cohort.
Abundances in the Herbig Ae star HD 101412: Abundance anomalies; Lambda Boo-Vega characteristics?
Creators: name: Cowley, C. R.
name: Hubrig, S.
name: González, J. F.
name: Savanov, I.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context: Recent attention has been directed to abundance variations among very young stars. Aims: To perform a detailed abundance study of the Herbig Ae star HD 101412, taking advantage of its unusually sharp spectral lines. Methods: High-resolution spectra are measured for accurate wavelengths and equivalent widths. Balmer-line fits and ionization equlibria give a relation between Teff, and log(g). Abundance anomalies and uncertain reddening preclude the use of spectral type or photometry to fix Teff. Excitation temperatures are used to break the degeneracy between Teff and log(g). Results: Strong lines are subject to an anomalous saturation that cannot be removed by assuming a low microturbulence. By restricting the analysis to weak (<= 20 m[A]) lines, we find consistent results for neutral and ionized species, based on a model with Teff = 8300K, and log(g)=3.8. The photosphere is depleted in the most refractory elements, while volatiles are normal or, in the case of nitrogen, overabundant with respect to the sun. The anomalies are unlike those of Ap or Am stars. Conclusions: We suggest the anomalous saturation of strong lines arises from heating of the upper atmospheric layers by infalling material from a disk. The overall abundance pattern may be related to those found for the Lambda Boo stars, though the depletions of the refractory elements are milder, more like those of Vega. However, the intermediate volatile zinc is depleted, precluding a straightforward interpretation of the abundance pattern in terms of gas-grain separation.
description: Accepted for publication in Astronomy and Astrophysics; 7 pages, 7 figs., 2 tables