cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Myorycteropus africanus MacInnes 1956
Creators: name: Lehmann, Thomas
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Tubulidentata
Orycteropodidae
Myorycteropus
Myorycteropus africanus

description: SPECIES MYORYCTEROPUS CF. AFRICANUS KENYA
 Material: Various cranial and post-cranial elements, usually found isolated, described by MacInnes (1956) and Pickford (1975), or yet unpublished (NHM M 21542, housed at the NHM, London; KNM MW 184– KNM MW 189; KNM MW 484; KNM MW 537; KNM MW 649; KNM RU 3048–3061; KNM RU 3590; KNM RU 5767, housed at the NMK, Nairobi).
 Remarks: The Specimen NHM M 21542 might correspond to the left talus quoted by MacInnes (1956) as ‘unnumbered from R.1 series of Rusinga’. Specimens KNM MW 184– KNM MW 189 (relabelled) correspond to the published specimens KNM MW 84– KNM MW 89 of Pickford (1975). This author also attributed some of these specimens to ‘ O. minutus ’ (but see discussion below).
 Locality and age: Rusinga Island and Mfwangano (Kenya), dated to around 17.8-Mya (Drake et al., 1988).
 Discussion: The material considered here has been exclusively found at Rusinga Island and Mfwangano, where the holotype and paratype of M. africanus were also discovered. These skeletal elements have, however, no counterparts in the hypodigm of the aforementioned species, or are too weathered to display any diagnostic features to help with their determination. Their size and shape are nonetheless close enough to M. africanus to place the material close to that species.
description: Published as part of Lehmann, Thomas, 2009, Phylogeny and systematics of the Orycteropodidae (Mammalia, Tubulidentata), pp. 649-702 in Zoological Journal of the Linnean Society 155 (3) on page 680, DOI: 10.1111/j.1096-3642.2008.00460.x, http://zenodo.org/record/5445097
title: A Working Session on 3-D City Modeling
Creators: name: Dokonal, Wolfgang
name: Martens, Bob
Publisher: name: TU Wien
Year: 2001
Subjects: Urban Modeling
3-D Modeling
Collaboration
City Information
Model Adaptation

description: On the occasion of a presentation on a city model for Graz at the eCAADe-conference in Weimar (2000), some attendees informed us about their previous work in this field and the idea of preparing a working session with collegues involved in 3-D city modeling was born. During the initial phase of research for this eCAADe conference activity it turned out that a large number of city models has been created in the course of time for different reasons resp. purposes. Therefore a rich variety in the production of city models can be noticed. This working session on 3-D city modeling brings together experts focusing on different aspects concerning the creation and use of city models, such as data input, data structure, data storage and data quality. Also the definition of a perspective on the future of 3-D city modeling can be regarded as an important topic. In this paper a rough overview on the different submissions will be presented. Furthermore three blitz statements are incorporated as time was too short to produce a full paper. Both with the individual contributions as with this overview paper it is intended to present a knowledge-base to this working field. Finally, the start for a growing bibliography was made in order to support future work in this area.
Reaction-diffusion dynamics: confrontation between theory and experiment in a microfluidic reactor
Creators: name: Baroud, Charles N.
name: Okkels, Fridolin
name: Menetrier, Laure
name: Tabeling, Patrick
Publisher: name: arXiv
Year: 2002
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We confront, quantitatively, the theoretical description of the reaction-diffusion of a second order reaction to experiment. The reaction at work is \ca/CaGreen, and the reactor is a T-shaped microchannel, 10 $μ$m deep, 200 $μ$m wide, and 2 cm long. The experimental measurements are compared with the two-dimensional numerical simulation of the reaction-diffusion equations. We find good agreement between theory and experiment. From this study, one may propose a method of measurement of various quantities, such as the kinetic rate of the reaction, in conditions yet inaccessible to conventional methods.
Additional file 3 of Does the incorporation of strontium into calcium phosphate improve bone repair? A meta-analysis
Creators: name: Yan, Ming-Dong
name: Ou, Yan-Jing
name: Lin, Yan-Jun
name: Liu, Rui-Min
name: Fang, Yan
name: Wu, Wei-Liang
name: Zhou, Lin
name: Yao, Xiu
name: Chen, Jiang
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 3: Supplementary figures.
A bound for the conductor of an open subgroup of GL2 associated to an elliptic curve
Creators: name: Jones, Nathan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11G05, 11F80

description: Given an elliptic curve $E$ without complex multiplication defined over a number field $K$, consider the image of the Galois representation defined by letting Galois act on the torsion of $E$. Serre's open image theorem implies that there is a positive integer $m$ for which the Galois image is completely determined by its reduction modulo $m$. In this note, we prove a bound on the smallest such $m$ in terms of standard invariants associated with $E$. The bound is sharp and improves upon previous results.
description: This replacement contains minor revisions and includes MAGMA scripts in an appendix for all computations referenced in the paper
Model-based simulation of glycaemic effect and body weight loss when switching from semaglutide or dulaglutide to once weekly tirzepatide
Creators: name: Urva, Shweta
name: Levine, Joshua A.
name: Schneck, Karen
name: Tang, Cheng Cai
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: To evaluate the efficacy endpoints of HbA1c and body weight loss after switching from the GLP-1 receptor agonists, semaglutide or dulaglutide, to treatment with the GIP/GLP-1 receptor agonist (RA) tirzepatide. Models were developed and validated to describe the HbA1c and weight loss time course for semaglutide (SUSTAIN 1-10), dulaglutide (AWARD-11) and tirzepatide (SURPASS 1-5, phase 3 global T2D program). The impact of switching from once weekly GLP-1 RAs to tirzepatide was described by simulating the efficacy time course. Semaglutide and dulaglutide doses were escalated in accordance with their respective labels. Model-predicted mean decreases from baseline in HbA1c and body weight for semaglutide 0.5 mg, 1 mg, and 2 mg were 1.22 to 1.79% and 3.62 to 6.87 kg respectively, at Week 26. Model-predicted mean decreases from baseline in HbA1c and body weight for dulaglutide 1.5 mg, 3 mg and 4.5 mg were 1.53 to 1.84% and 2.55 to 3.71 kg respectively, at Week 26. After switching to tirzepatide 5, 10 and 15 mg HbA1c reductions were predicted to range between 1.95 to 2.46% and body weight reductions between 6.50 to 12.1 kg by Week 66. In this model-based simulation, switching from approved maintenance doses of semaglutide or dulaglutide to tirzepatide, even at the lowest approved maintenance dose of 5 mg, showed the potential to further improve HbA1c and body weight reductions. Type 2 diabetes is a disease of elevated blood sugar levels. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a type of medication used to treat type 2 diabetes that work on GLP-1 receptors in the body. Semaglutide and dulaglutide are examples of GLP-1 RAs, which lower blood sugar and body weight. Tirzepatide is a newer medication, which works on both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors. It reduces blood sugar and body weight in people living with type 2 diabetes. Healthcare professionals and patients are interested in how switching medication from semaglutide or dulaglutide to tirzepatide might change blood glucose levels and body weight. However, because tirzepatide is a newer medication, there is not much information available on this aspect. Data from clinical trials of these medications were used to predict the effects of switching from semaglutide or dulaglutide to tirzepatide. These model-based simulations showed that switching to tirzepatide may further reduce HbA1c (a measure of blood sugar) and body weight. This may provide useful information to healthcare professionals and patients when making decisions about treatment with these medications.
Effective Potential for Emergent Majorana Fermions in Superconductor Systems
Creators: name: Teixeira, Allison W.
name: Carvalho-Santos, Vagson. L.
name: Fonseca, Jakson M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Majorana fermions cannot be found in nature as a free fundamental particle. Nevertheless, in condensed matter systems, they can emerge as a collective excitation. In this work, using functional integration techniques, we calculated the effective potential for emergent Majorana fermions in the Kitaev chain. In this case, we have shown how the superconductor parameter behaves as a function of temperature. Furthermore, we considered surface-induced superconductivity in a Topological Insulator and calculated the effective potential for emergent Majorana fermions in this system. In the case of an s-wave superconductor, we obtained a gap equation equivalent to that one appearing in a quasi-two-dimensional Dirac electronic system, a candidate to explain high-Tc superconductivity. Finally, for the p-wave superconductor, we have obtained a critical value of the electronelectron interaction in the surface of the Topological Insulator, determining the existence or not of induced superconductivity, a remarkable result to guide experiments
description: 6 pages, 3 figures, Accepted in Physics Letters A
title: Rollenbilder im Wandel: Vereinbarkeit von Familie und Beruf in der Allgemeinmedizin – Chancen, Hemmnisse und Herausforderungen
Creators: name: Stengel, Sandra
name: Kotowicz, Martin
name: Nohl-Deryk, Pascal
name: Blank, Wolfgang
name: Schwill, Simon
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Vereinbarkeit von Familie und Beruf ist ein zentrales Thema für die Tätigkeit in der Allgemeinmedizin und damit für die Gewinnung des allgemeinmedizinischen ärztlichen Nachwuchses [ref:1], [ref:2]. Bei vorhandenem Hausarztmangel ergibt sich ein[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
Additional file 3 of Pathological and oncological outcomes of pylorus-preserving versus conventional distal gastrectomy in early gastric cancer: a systematic review and meta-analysis
Creators: name: Hou, Sen
name: Liu, Fan
name: Gao, Zhidong
name: Ye, Yingjiang
Publisher: name: figshare
Year: 2022
Subjects: Space Science
Medicine
Cell Biology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Additional file 3. The risk of bias among included studies. a. risk of bias of RCSs; b. risk of bias of RCTs.
title: Deciphering the Functional Roles of Centrosomal Protein 55 (CEP55) in Development and Cancer
Creators: name: Rashidieh, Behnam
Publisher: name: Griffith University
Year: 2020
Subjects: subject: Centrosomal protein
subject: CEP55
subject: knockout mouse model
subject: in vivo
subject: characterization
subject: embryogenesis

description: Centrosomal protein CEP55 is a critical regulator of cytokinesis, and its deregulation has been linked to tumorigenesis. Loss of function mutations in Cep55 have also been shown to perturb embryogenesis, particularly affecting neural development. Cep55 expression in cells must be tightly regulated, as both overexpression and reduced levels of expression can cause cytokinetic abscission defects leading to genomic instability. CEP55 also promotes PI3K/AKT signaling which confers a survival advantage to cancer cells. However, despite more than a decade of research into characterizing this protein, the molecular function of CEP55 during tumorigenesis and embryonic development in mammals is not well defined. In this thesis, we have generated a Cep55 knockout (Cep55-/-) mouse model, which is the first in vivo knockout model for this gene to our knowledge. Cep55-/- mice exhibited late embryonic lethality associated with a wide range of neural defects. We showed that Cep55-/- embryos at E14.5 exhibit depleted neural stem cells in the ventricular zone. This was caused by a significant decrease in proliferation with a concomitant increase in apoptosis of radial glial (RGCs : PAX6+), intermediate progenitor cells (IPC: TBR2+) and postmitotic neurons (PMN: TBR1+). As a consequence, we observed reduced numbers of neurons in the cortical plate at later stages of embryonic development. [...]
Additional file 1 of Knowledge of and attitudes towards erosive tooth wear among students of two Chinese universities
Creators: name: Hong, Deng-wei
name: Lin, Xiu-jiao
name: Wiegand, Annette
name: Yu, Hao
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1 : Supplementary Table 1: Questionnaire used in this study.
title: Dependance-Gründung in der Allgemeinmedizin: Wie geht das praktisch?
Creators: name: Woestmann, Barbara
name: Lubbe, Beate
name: Huenges, Bert
name: Rusche, Herbert
name: Leeuw, Bettina
name: Streitlein-Böhme, Irmgard
name: Vollmar, Horst Christian
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: An der Ruhr-Universität Bochum (RUB) absolvieren seit dem WiSe 2016/17 pro Jahrgang ca. 60 von insgesamt 300 Studierenden die klinische Ausbildung ab dem 7. Semester in Ostwestfalen-Lippe (OWL). Eine Motivation für die Gründung der ersten Dependance im ländlichen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
Soft charges from the geometry of field space
Creators: name: Riello, Aldo
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Infinite sets of asymptotic soft-charges were recently shown to be related to new symmetries of the $S$-matrix, spurring a large amount of research on this and related questions. Notwithstanding, the raison-d'être of these soft-charges rests on less firm ground, insofar as their known derivations through generalized Noether procedures tend to rely on the fixing of (gauge-breaking) boundary conditions rather than on manifestly gauge-invariant computations. In this article, we show that a geometrical framework anchored in the space of field configurations singles out the known leading-order soft charges in gauge theories. Our framework unifies the treatment of finite and infinite regions, and thus it explains why the infinite enhancement of the symmetry group is a property of asymptotic null infinity and should not be expected to hold within finite regions, where at most a finite number of physical charges -- corresponding to the reducibility parameters of the quasi-local field configuration -- is singled out. As a bonus, our formalism also suggests a simple proposal for the origin of magnetic-type charges at asymptotic infinity based on spacetime (Lorentz) covariance rather than electromagnetic duality.
description: Published version: Major improvements in the exposition, and new results on the relationship with the Ashtekar-Streubel phase space. 14 pages + appendices
Humanistic burden of mucopolysaccharidoses: a systematic literature review
Creators: name: Li, Joyce Wai-Yin
name: Yan, Kevin
name: Balijepalli, Chakrapani
name: Druyts, Eric
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: To systematically review the literature and summarize the health-related quality-of-life (HRQoL) of patients undergoing treatment for mucopolysaccharidoses (MPS), a rare, hereditary lysosomal storage disorder. A systematic review was performed in accordance with PRISMA guidelines to identify research studies that describe the humanistic burden of MPS. A comprehensive literature search was conducted in EMBASE, MEDLINE, and eligible conferences were screened to include applicable abstracts. Of 870 identified articles, 15 studies reported the HRQoL burden of patients with MPS undergoing or with a history of ERT and/or HSCT. These studies include patients of MPS I (n = 2), MPS II (n = 4), MPS IV (n = 6), MPS VI (n = 1), and subtype not mentioned (n = 2). Although the quality-of-life of MPS patients is influenced by time of diagnosis, pain, cognitive involvement, severity of disease, mobility, dependence, and time of treatment initiation, the HRQoL scores of MPS patients across all the scales were below the median reference population scores across all dimensions. This is seen in comparison to healthy participants but also in comparison to patients with other chronic illnesses. The multi-organ involvement, neurological impairment, pain, and morbidity associated with the condition not only affects activity of daily living but also affects social functioning, emotional status, employment status among adults, and school functioning among children. This systematic literature review revealed the substantial humanistic burden of individuals affected by MPS as well as caregivers. Significant variation in HRQoL scores was observed, however studies indicate that the quality-of-life of MPS patients is influenced primarily by severity of disease (MPS type and phenotype), and then by time of diagnosis, pain, cognitive involvement, mobility, dependence, and time of treatment initiation. Further studies are needed to assess the global humanistic burden of MPS, particularly in MPS III, VI, VII, and IX subtypes, in adults, and for a longer follow-up period. Considering the vast array of HRQoL assessment tools available and used in this study, researchers should also consider using scales with condition-specific measures to ensure appropriate estimates of effectiveness.
A sharp bound for an eigenvalue moment of the one-dimensional Schroedinger operator
Creators: name: Hundertmark, Dirk
name: Lieb, Elliott H.
name: Thomas, Lawrence E.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We give a proof of the Lieb-Thirring inequality in the critical case $d=1$, $γ= 1/2$, which yields the best possible constant.
description: Revised version. 14 pages, Latex2e, no figures. Some typos on p.3 corrected and journal ref added
Total variation based community detection using a nonlinear optimization approach
Creators: name: Cristofari, Andrea
name: Rinaldi, Francesco
name: Tudisco, Francesco
Publisher: name: arXiv
Year: 2019
Subjects: subject: Social and Information Networks (cs.SI)
subject: Optimization and Control (math.OC)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 49M20, 65K10, 91D30, 91C20

description: Maximizing the modularity of a network is a successful tool to identify an important community of nodes. However, this combinatorial optimization problem is known to be NP-complete. Inspired by recent nonlinear modularity eigenvector approaches, we introduce the modularity total variation $TV_Q$ and show that its box-constrained global maximum coincides with the maximum of the original discrete modularity function. Thus we describe a new nonlinear optimization approach to solve the equivalent problem leading to a community detection strategy based on $TV_Q$. The proposed approach relies on the use of a fast first-order method that embeds a tailored active-set strategy. We report extensive numerical comparisons with standard matrix-based approaches and the Generalized RatioDCA approach for nonlinear modularity eigenvectors, showing that our new method compares favourably with state-of-the-art alternatives.
Search for a generic heavy Higgs at the LHC
Creators: name: Chen, Xin
name: Xu, Yue
name: Wu, Yongcheng
name: Kuang, Yu-Ping
name: Wang, Qing
name: Chen, Hang
name: Hsu, Shih-Chieh
name: Hu, Zhen
name: Li, Congqiao
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A generic heavy Higgs has both dim-4 and effective dim-6 interactions with the Standard Model (SM) particles. The former has been the focus of LHC searches in all major Higgs production channels, just as the SM one, but with negative results so far. If the heavy Higgs is connected with Beyond Standard Model (BSM) physics at a few TeV scale, its dim-6 operators will play a very important role - they significantly enhance the Higgs momentum, and reduce the SM background in a special phase space corner to a level such that a heavy Higgs emerges, which is not possible with dim-4 operators only. We focus on the associated VH production channel, where the effect of dim-6 operators is the largest and the SM background is the lowest. Main search regions for this type of signal are identified, and substructure variables of boosted jets are employed to enhance the signal from backgrounds. The parameter space of these operators are scanned over, and expected exclusion regions with 300 fb$^{-1}$ and 3 ab$^{-1}$ LHC data are shown, if no BSM is present. The strategy given in this paper will shed light on a heavy Higgs which may be otherwise hiding in the present and future LHC data.
Additional file 1 of Dihydromyricetin ameliorated nonalcoholic steatohepatitis in mice by regulating the composition of serous lipids, bile acids and ileal microflora
Creators: name: Miao, Xiaolei
name: Luo, Ping
name: Liu, Jiao
name: Wang, Junjun
name: Chen, Yong
Publisher: name: figshare
Year: 2023
Subjects: Biochemistry
Molecular Biology
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Computational Biology

description: Additional file 1: Table S1. Primer sequences used for RT-qPCR of the tested genes and RT-qPCR reaction conditions. Table S2. The serum bile acids levels (n=7).
Optimizing city-scale traffic through modeling observations of vehicle movements
Creators: name: Yang, Fan
name: Vereshchaka, Alina
name: Lepri, Bruno
name: Dong, Wen
Publisher: name: arXiv
Year: 2019
Subjects: subject: Social and Information Networks (cs.SI)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The capability of traffic-information systems to sense the movement of millions of users and offer trip plans through mobile phones has enabled a new way of optimizing city traffic dynamics, turning transportation big data into insights and actions in a closed-loop and evaluating this approach in the real world. Existing research has applied dynamic Bayesian networks and deep neural networks to make traffic predictions from floating car data, utilized dynamic programming and simulation approaches to identify how people normally travel with dynamic traffic assignment for policy research, and introduced Markov decision processes and reinforcement learning to optimally control traffic signals. However, none of these works utilized floating car data to suggest departure times and route choices in order to optimize city traffic dynamics. In this paper, we present a study showing that floating car data can lead to lower average trip time, higher on-time arrival ratio, and higher Charypar-Nagel score compared with how people normally travel. The study is based on optimizing a partially observable discrete-time decision process and is evaluated in one synthesized scenario, one partly synthesized scenario, and three real-world scenarios. This study points to the potential of a "living lab" approach where we learn, predict, and optimize behaviors in the real world.
Model-based simulation of glycaemic effect and body weight loss when switching from semaglutide or dulaglutide to once weekly tirzepatide
Creators: name: Urva, Shweta
name: Levine, Joshua A
name: Schneck, Karen
name: Tang, Cheng Cai
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: To evaluate the efficacy endpoints of HbA1c and body weight loss after switching from the GLP-1 receptor agonists, semaglutide or dulaglutide, to treatment with the GIP/GLP-1 receptor agonist (RA) tirzepatide. Models were developed and validated to describe the HbA1c and weight loss time course for semaglutide (SUSTAIN 1-10), dulaglutide (AWARD-11) and tirzepatide (SURPASS 1-5, phase 3 global T2D program). The impact of switching from once weekly GLP-1 RAs to tirzepatide was described by simulating the efficacy time course. Semaglutide and dulaglutide doses were escalated in accordance with their respective labels. Model-predicted mean decreases from baseline in HbA1c and body weight for semaglutide 0.5 mg, 1 mg, and 2 mg were 1.22 to 1.79% and 3.62 to 6.87 kg respectively, at Week 26. Model-predicted mean decreases from baseline in HbA1c and body weight for dulaglutide 1.5 mg, 3 mg and 4.5 mg were 1.53 to 1.84% and 2.55 to 3.71 kg respectively, at Week 26. After switching to tirzepatide 5, 10 and 15 mg HbA1c reductions were predicted to range between 1.95 to 2.46% and body weight reductions between 6.50 to 12.1 kg by Week 66. In this model-based simulation, switching from approved maintenance doses of semaglutide or dulaglutide to tirzepatide, even at the lowest approved maintenance dose of 5 mg, showed the potential to further improve HbA1c and body weight reductions. Type 2 diabetes is a disease of elevated blood sugar levels. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a type of medication used to treat type 2 diabetes that work on GLP-1 receptors in the body. Semaglutide and dulaglutide are examples of GLP-1 RAs, which lower blood sugar and body weight. Tirzepatide is a newer medication, which works on both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors. It reduces blood sugar and body weight in people living with type 2 diabetes. Healthcare professionals and patients are interested in how switching medication from semaglutide or dulaglutide to tirzepatide might change blood glucose levels and body weight. However, because tirzepatide is a newer medication, there is not much information available on this aspect. Data from clinical trials of these medications were used to predict the effects of switching from semaglutide or dulaglutide to tirzepatide. These model-based simulations showed that switching to tirzepatide may further reduce HbA1c (a measure of blood sugar) and body weight. This may provide useful information to healthcare professionals and patients when making decisions about treatment with these medications.
title: The New Role of Professional Organisations in the Management of Scientific Knowledge
Creators: name: Turk, Ziga
name: Björk, Bo-Christer
name: Martens, Bob
name: Petrinja, Etiel
Publisher: name: TU Wien
Year: 2002
Subjects: scientific knowledge management

description: The Internet is changing not only the way the architects and engineers work, but also how the scientists collaborate. In the paper based world, professional organisations, such as the CIB and scientific publishers provided for getting the right people together and for making sure their work gets distributed to their peers. Electronic networks, such as the Internet, are providing the scientists the means to take those activities into their own hands. In the paper we present the goals of an EU project called SciX. The goal of SciX is to analyse the business processes of the scientific publishing, invent new publication models and through a series of pilots demonstrate how this should work. In the envisioned scenarios, professional organisations such as the CIB play an important role. Their members are the potential users of SciX's platforms, authors and readers of the papers. Organisations could also become the publishers and archivers of the knowledge created within their respective community. The goal of the paper is to engage the members of the CIB-W78 community in the developments in SciX, to help fineshaping the goals, defining the requirements and monitoring the usability of the pilots.
Regimes of classical simulability for noisy Gaussian boson sampling
Creators: name: Qi, Haoyu
name: Brod, Daniel J.
name: Quesada, Nicolás
name: García-Patrón, Raúl
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: As a promising candidate for exhibiting quantum computational supremacy, Gaussian Boson Sampling (GBS) is designed to exploit the ease of experimental preparation of Gaussian states. However, sufficiently large and inevitable experimental noise might render GBS classically simulable. In this work, we formalize this intuition by establishing a sufficient condition for approximate polynomial-time classical simulation of noisy GBS --- in the form of an inequality between the input squeezing parameter, the overall transmission rate and the quality of photon detectors. Our result serves as a non-classicality test that must be passed by any quantum computationalsupremacy demonstration based on GBS. We show that, for most linear-optical architectures, where photon loss increases exponentially with the circuit depth, noisy GBS loses its quantum advantage in the asymptotic limit. Our results thus delineate intermediate-sized regimes where GBS devices might considerably outperform classical computers for modest noise levels. Finally, we find that increasing the amount of input squeezing is helpful to evade our classical simulation algorithm, which suggests a potential route to mitigate photon loss.
description: 13 pages, 4 figures, final version accepted for publication in Physical Review Letters
Orycteropus afer Makapansgat
Creators: name: Lehmann, Thomas
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Tubulidentata
Orycteropodidae
Orycteropus
Orycteropus afer

description: SPECIES ORYCTEROPUS CF. AFER MAKAPANSGAT
 Material: A right M 1 (M8271), and a fragment of right hemimandible with broken M 1 and complete M 2 (M8272), described by Kitching (1963) as O. cf. afer. The material is housed at the Bernard Price Institute, University of the Witwatersrand, Johannesburg (South Africa).
 Locality and age: Makapansgat (South Africa), dated to between 3.06 and 3.32 Mya (MacFadden, Brock & Partridge, 1979).
 Discussion: Lehmann (2004) revised the anatomical position of the different elements as given above. The upper and lower molars are rectangular in shape, and present deep lingual and vestibular grooves. Therefore, the attribution to the redefined genus Orycteropus is confirmed. The revised dimensions of the teeth ‘are not significantly different from corresponding data obtained from extant aardvark’ (Lehmann, 2004: 313), but are large. These teeth are closer to O. afer than to O. crassidens in their size, and do not belong to O. djourabensis because they show a deep lingual groove on the upper molar. However, until further material is discovered, I recommend keeping the cautious determination made by Kitching (1963).
description: Published as part of Lehmann, Thomas, 2009, Phylogeny and systematics of the Orycteropodidae (Mammalia, Tubulidentata), pp. 649-702 in Zoological Journal of the Linnean Society 155 (3) on pages 684-685, DOI: 10.1111/j.1096-3642.2008.00460.x, http://zenodo.org/record/5445097
On zeros of polynomials orthogonal over a convex domain
Creators: name: Andrievskii, V. V.
name: Pritsker, I. E.
name: Varga, R. S.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Complex Variables (math.CV)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 30C10, 30C15, 30C85, 41A10

description: We establish a discrepancy theorem for signed measures, with a given positive part, which are supported on an arbitrary convex curve. As a main application, we obtain a result concerning the distribution of zeros of polynomials orthogonal on a convex domain.
description: 24 pages; to appear in Constr. Approx
MOESM1 of Evaluation of surfactin synthesis in a genome reduced Bacillus subtilis strain
Creators: name: Geissler, Mareen
name: KĂźhle, Ines
name: Heravi, Kambiz Morabbi
name: Altenbuchner, Josef
name: Henkel, Marius
name: Hausmann, Rudolf
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1: Table S1. Plasmids used in this study. Table S2. Oligonucleotides used in this study. Table S3. Strains used in this study.
Transonic boundary layer transition prediction over wing sections with embedded DG spectral/hp discretisations
Creators: name: Lyu, Ganlin
Publisher: name: Imperial College London
Year: 2023

description: The prediction of laminar boundary layer transition is still under intensive investigations in the fluid instability community, particularly when complicated factors (e.g realistic geometries) are involved. In this thesis we introduce an open-source and unified framework for boundary layer transition analysis at transonic conditions and over wing sections where surface irregularities may present. Different computational tools are integrated in the framework, and therefore overcomes the difficulties of two separate and usually quite disparate processes, i.e. the computation of baseflow and disturbances, when using e^N transition prediction method. To reduce the computational cost, a near-body reduced domain is adopted with boundary conditions enforced to be compatible with a computationally cheaper three-dimensional (3D) RANS simulation. It is desirable to enforce a consistent pressure distribution. However, the pressure compatibility is not typically the case when using the standard Riemann inflow boundary condition, while not all modified boundary condition enforcements lead to a stable simulation. We therefore revisit the Riemann problem adopted in many DG-based high-fidelity formulations and develop a useful analysis approach to construct boundary conditions for the inviscid term based on a linearized one-dimensional model. In-depth analysis and results are also presented. We next apply this analysis framework to investigate the transition performance using a wing section of CRM-NLF model for both clean and gapped geometries. In 3D gapped case, we find self-sustained oscillations in the small-sized gap which excites travelling waves. An incompressible swept plate flow is simulated to investigate the hydrodynamic instability that drives the oscillation inside the gap. It is found that the traveling waves correspond to a BiGlobal mode inside the gap and possess a convective nature. This new discovery suggests the presence of different physics compared with a gapped non-swept case, and thus motivates our in-depth investigations in future works.
Distribution, Benefits, Challenges, and Recommendations of Urban Agriculture in New York City
Creators: Lin, Ruoran
Publisher: name: Columbia University
Year: 2018
Subjects: City planning
Urban agriculture
Food security
Sustainability
Land use, Urban

description: Urban Agriculture (UA) is a widely considered food policy strategy to address local food issues. A heated discussion is ongoing among city politicians, farmers and gardeners, community members and other stakeholders about whether the benefits of UA outweigh its challenges, and whether to develop or abandon a comprehensive UA plan. Employing a two-step, quantitative-qualitative method at the macro and micro scales, this study attempts to make a meaningful contribution to this debate through a full-range evaluation of UA distribution and sustainability in New York City (NYC), which has the largest number of urban agriculture projects in the nation. First, this study explored the spatial pattern of citywide UA distribution, conducted a descriptive analysis of UA performance, and examined the statistical association between UA sustainable development and 25 influential indicators in terms of demography, environment, economy, and equity. Second, it investigated two case studies, the individual urban farm and community garden, to provide in-depth insights into UA benefits and challenges. This study concluded that UA’s distribution in NYC had specific spatial clustering patterns in the South Bronx and northern Brooklyn. Citywide UA made contributions to society through its mature Community-Supported Agriculture networks, its huge green-industry educational programs, and its high eco-value circulation systems. The city was faced with UA challenges in terms of immigrant separation, non-significant economic contributions, land shortage, health imbalance, and crime occurrence. For future UA development and regulations, the recommendations were to construct an accurate and complete UA database, amend the UA zoning ordinances, promote citywide cooperation, ensure a multiple-stakeholder process, ensure social equity, and address the land demand conflicts between UA and other land use activities.
BUXGALTERIYA HISOBINI RAQAMLI TEXNOLOGIYALAR ASOSIDA QAYTA TASHKIL ETISHNING KONSEPTUAL JIHATLARI
Creators: name: Abdusalomova, Nafosat
Publisher: name: Zenodo
Year: 2024

description: Bugungi shiddat bilan rivojlanayotgan biznes landshaftida buxgalteriya hisobi jarayonlari raqamli texnologiyalarning integratsiyasi tufayli tubdan o‘zgardi. Ushbu maqola qayta tashkil etishning konseptual xususiyatlarini va uning korxonalar uchun oqibatlarini o'rganadi. Raqamli texnologiyalardan foydalangan holda, tashkilotlar samaradorlik, aniqlik va qaror qabul qilish imkoniyatlarini oshirish uchun buxgalteriya hisobini soddalashtirishi mumkin.
title: Historical Aerial Image Orientation
Creators: name: Karel, Wilfried
Publisher: name: TU Wien
Year: 2025
Subjects: historical aerial images
multitemporal feature matching

description: https://github.com/TUW-GEO/selorecon
description: Aerial images are a key data source when it comes to analyzing changes of the environment over time. This has a number of reasons. While the oldest available imagery typically dates back many decades, today's competing wide-area surveying methods provide more recent data only. Furthermore, unlike maps, aerial imagery is uninterpreted, which avoids potential biases, and allows for a wider range of applications. For quantifying changes over time, the orientation of images in a common reference frame is a precondition, however. This talk presents recent endeavors at TU Wien to achieve this goal more accurately and efficiently, including aspects like robust bundle adjustment strategies, and the search for homologous points within and across image data sets from different points in time, and covering civil and reconnaissance imagery taken since the 1940ies, including a Romanian data set from 1971.
Low-Energy Electron-Beam Diagnostics Based on the Optical Transition Radiation
Creators: name: Aleinik, A. N.
name: Chefonov, O. V.
name: Kalinin, B. N.
name: Naumenko, G. A.
name: Potylitsyn, A. P.
name: Saruev, G. A.
name: Sharafutdinov, A. F.
name: Wagner, W.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: A possibility of a few MeV electron beam diagnostics (Lorentz factor ~ 10) using polarization characteristics of the optical transition radiation (OTR) have been considered. Determinaton of the electron beam divergence have been performed with technique based on the OTR measurements. The technique is based on measuring the ratio R=Imin/Imax, where Imin(Imax) is the photon yield in the minimum (maximum) of OTR angular distribution. It is shown that the value of R can be obtained also from the measurement of the so-called psi-scan of the OTR yield registered by a fixed detector with the aperture < gamma^(-1) by varying the target tilt angle with respect to the electron-beam. The experiment curried out at 6.1 MeV Tomsk microtron has demonstrated the feasibility of the technique proposed.
The First Eigenvalue of the Dirac Operator on Quaternionic Kaehler Manifolds
Creators: name: Kramer, W.
name: Semmelmann, U.
name: Weingart, G.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: In a previous paper we proved a lower bound for the spectrum of the Dirac operator on quaternionic Kaehler manifolds. In the present article we show that the only manifolds in the limit case, i.e. the only manifolds where the lower bound is attained as an eigenvalue, are the quaternionic projective spaces. We use the equivalent formulation in terms of the quaternionic Killing equation and show that a nontrivial solution defines a parallel spinor on the associated hyperkaehler manifold.
description: 19 pages, LaTeX2e, fullpage style
Identifying the Influential Inputs for Network Output Variance Using Sparse Polynomial Chaos Expansion
Creators: name: Liu, Zhanlin
name: Banerjee, Ashis G.
name: Choe, Youngjun
Publisher: name: arXiv
Year: 2019
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Sensitivity analysis (SA) is an important aspect of process automation. It often aims to identify the process inputs that influence the process output's variance significantly. Existing SA approaches typically consider the input-output relationship as a black-box and conduct extensive random sampling from the actual process or its high-fidelity simulation model to identify the influential inputs. In this paper, an alternate, novel approach is proposed using a sparse polynomial chaos expansion-based model for a class of input-output relationships represented as directed acyclic networks. The model exploits the relationship structure by recursively relating a network node to its direct predecessors to trace the output variance back to the inputs. It, thereby, estimates the Sobol indices, which measure the influence of each input on the output variance, accurately and efficiently. Theoretical analysis establishes the validity of the model as the prediction of the network output converges in probability to the true output under certain regularity conditions. Empirical evaluation on two manufacturing processes shows that the model estimates the Sobol indices accurately with far fewer observations than a state-of-the-art Monte Carlo sampling method.
Synchrotron radiation contributions to optical diffraction radiation measurements
Creators: name: Naumenko, G. A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: If we try to measure the backward optical diffraction radiation (BODR) of high energy electrons from a conductive slit or a semi infinitive plate, the electron beam will pass thru the bending or steering magnets or magnet lenses before striking the target. The synchrotron radiation (SR) from these magnets can obscure the BODR measurements. An analysis of the properties of SR from these magnets is in this paper presented. A model based on the modified Lenar Wikherd potentials was created, and the SR angular distribution from relativistic electrons in bending and steering magnets for different conditions of radiation in the optical region was calculated. The analysis shows, that for the conditions of the KEK ATF extraction line, the intensity of SR exceeds that of the backward optical transition radiation (BOTR) from the conducting targets, and it is much lager than the intensity of the BODR. The SR intensity from the steering magnets depends on its tuning and may be comparable to BOTR. Thus, these results it is seen, that the problem of separation of the BODR and SR in the BODR measurements is important. Two methods resolving of this problem is in this article suggested.
Bordism-finiteness and semi-simple group actions
Creators: name: Dessai, Anand
Publisher: name: arXiv
Year: 2000
Subjects: subject: Geometric Topology (math.GT)
subject: Algebraic Topology (math.AT)
subject: K-Theory and Homology (math.KT)
subject: FOS: Mathematics
subject: 19L47; 55R91; 57R75; 57S15; 58D19

description: We give bordism-finiteness results for manifolds with semi-simple group action. Consider the class of oriented manifolds which admit a circle action with isolated fixed points such that the action extends to an $S^3$-action with fixed point. We exhibit various subclasses, characterized by an upper bound for the Euler characteristic and properties of the first Pontrjagin class, which contain only finitely many oriented bordism types in any given dimension. Also we show finiteness results for homotopy complex projective spaces and complete intersections with $S^3$-action as above.
description: to appear in Geometriae Dedicata, minor changes, one reference changed
Multi Criteria Decision Making for Fresh Mango Supply Chain Risk Management: An ISM & TOPSIS-Based approach
Creators: name: Khairul Anam
name: Miad Bin Mostafiz
name: Shakil Shah
name: Ridoy Chandra Dhar
name: Sultan Ahmed
Publisher: name: BIHRM Supply Chain
Year: 2023

description: In Bangladesh, Mango is one of the most demandable fruits as well as called the "King of Fruits" for its exceptional taste and Nutrients. Mango is a perishable fruit that ripens quickly at room temperature. As a result, there are many risks associated with the Fresh Mango Supply Chain (FMSC). The primary goal of our research is to reduce potential mango waste by assessing risk factors and then implementing and evaluating mitigation techniques. Based on the literature review on risk management, several surveys and interviews were carried out to find potential risks and mitigation strategies. ISM (Iterative Structural Model) and TOPSIS (Technique for Order of Preference by Similarity to Ideal Solution) methodologies were applied to assess risks and mitigation strategies, respectively. Both methodologies are very effective MCDM (Multi-Criteria-Decision-Making) analysis techniques. Implementing the proposed risk management framework can help minimize the wastage of mangoes by approximately 15%. This would result in significant economic benefits for growers, shippers, and retailers, and it would also help to maximize the overall sustainability of the mango supply chain. The results indicate that mitigation strategies can significantly reduce wastage and will add value to FMSC. On this basis, by analyzing risk and applying these strategies, firms can earn profit and provide better customer satisfaction, as it will enhance supply chain sustainability and resilience by proactively identifying and addressing potential risks and increasing Bangladesh's economic growth. Minimizing waste eventually obtains the sustainability of a supply chain.