cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2: of Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control
Creators: name: MartĂ­Nez-Lumbreras, Santiago
name: Krysztofinska, Ewelina
name: Thapaliya, Arjun
name: Spilotros, Alessandro
name: Matak-Vinkovic, Dijana
name: Salvadori, Enrico
name: Roboti, Peristera
name: Nyathi, Yvonne
name: Muench, Janina
name: Roessler, Maxie
name: Svergun, Dmitri
name: High, Stephen
name: Isaacson, Rivka
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Figure S2. The SGTA-3xNNP/AAA-V5 mutant stimulates the accumulation of OP91 in discrete cytosolic inclusions. HeLa cells stably expressing OP91 under an inducible promoter were transiently transfected with either a control plasmid (PEX19-V5) or plasmids encoding V5-tagged SGTA variants as indicated, and then induced to express OP91. Cells were fixed, stained for opsin and the V5 epitope, and analyzed by fluorescence microscopy. Opsin-positive inclusions in SGTA-3xNNP/AAA-V5-expressing cells are indicated by arrows. Scale bar is 10Â Îźm. (PDF 19499 kb)
A sufficient condition for the similarity of a polynomially bounded operator to a contraction
Creators: name: Gamal', Maria
Publisher: name: arXiv
Year: 2018
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 47A60, 47A65

description: Let $T$ be a polynomially bounded operator, and let $\mathcal M$ be its invariant subspace. Suppose that $P_{\mathcal M^\perp}T|_{\mathcal M^\perp}$ is similar to a contraction, while $θ(T|_{\mathcal M})=0$, where $θ$ is a finite product of Blaschke products with simple zeros satisfying the Carleson interpolating condition (a Carleson--Newman Blaschke product). Then $T$ is similar to a contraction. It is mentioned that Le Merdy's example shows that the assumption of polynomially boundedness cannot be replaced by the assumption of power boundedness.
description: Translated from Zapiski nauchn. semin. POMI, v. 456, 2017
Dicranodromia spinulata Guinot 1995
Creators: name: Ahyong, Shane T.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Homolodromiidae
Dicranodromia
Dicranodromia spinulata

description: Dicranodromia spinulata Guinot, 1995 (Fig. 1C) Dicranodromia spinulata Guinot, 1995: 225–227, fig. 21a–c, 22A–B, 25D [type locality: New Caledonia, 23°10'S, 167°10'E; 675 m]. Material examined. Rock Garden cold seep: NIWA 34933, 1 male (cl 9.6 mm, cw 6.8 mm), 40°02.31– 02.47'S, 178°08.58–08.62'E, 730–747 m, TAN0616/06, 4 Nov 2006. Remarks. The single specimen of Dicranodromia spinulata constitutes the first record of the species, and only the third record of the family from New Zealand. Distribution. New Caledonia and now from Rock Garden cold seep, eastern New Zealand; 675–747 m (Guinot 1995; this study).
description: Published as part of Ahyong, Shane T., 2008, Deepwater crabs from seamounts and chemosynthetic habitats off eastern New Zealand (Crustacea: Decapoda: Brachyura), pp. 1-72 in Zootaxa 1708 (1) on page 11, DOI: 10.11646/zootaxa.1708.1.1, http://zenodo.org/record/5107434
Comment on "Critique of the foundations of time-dependent density functional theory" [Phys. Rev.A. 75, 022513 (2007)]
Creators: name: Maitra, Neepa T.
name: Burke, Kieron
name: van Leeuwen, Robert
Publisher: name: arXiv
Year: 2007
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: A recent paper (Phys. Rev A. 75, 022513 (2007), arXiv:cond-mat/0602020) challenges exact time-dependent density functional theory (TDDFT) on several grounds. We explain why these criticisms are either irrelevant or incorrect, and that TDDFT is both formally exact and predictive.
description: 4 pages; This is a Comment on the paper cited above, also at arXiv:cond-mat/0602020
Announcement of the Summer Session Supplement to Calendar 1967-68 Forty-ninth Session: July 2 to August 16, 1968
Creators: name: University Of British Columbia
Publisher: name: Vancouver : University of British Columbia
Year: 2017

description: Announcement of courses for the 49th summer session at the University of British Columbia, taking place from July 2nd to August 16th, 1968. Contains course schedule, course descriptions and details, fees, and other information about the session.
RuvB12 as a regulator of hTERT
Creators: name: Padraic Flavin
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Telomere maintenance is essential for the continued proliferation of tumour cells and is performed through the mechanism of telomerase activation or by a recombination-based process referred to as alternative lengthening of telomeres (ALT). The most important components of active telomerase are the reverse transcriptase enzyme (hTERT) and the non-coding RNA subunit (hTR). hTERT is the rate-limiting component and is highly regulated. The detection of genes that regulate either telomere maintenance mechanism is therefore of potential therapeutic significance. To address this, the study used stable isotope labelling of/with amino acids in cell culture (SILAC) to compare the proteomes of 2 cell lines, 6G and 1-3C that had been previously derived from a single SV4O-immortalised jejunal fibroblast cell. Both cell lines are therefore genetically similar except for the fact that the 6G and 1-3C lines use different TMMs (telomerase and ALT respectively) to counteract telomere attrition. An ATPase-dependent DNA helicase protein called RuvBI2 was found to be relatively overexpressed in the 6G cell line. RuvBI2 is known to be involved in the control of gene expression and a putative role in hTERT regulation was investigated. siRNA knockdown of RuvBI2 reduced hTERT protein levels in the 6G cell line. RuvB12 was able to interact with the hTERT promoter and was also shown to upregulate hTERT gene transcription. Collectively the data in this study suggest that RuvBI2 is a positive regulator of hTERT gene expression and this observation supports the existing body of data that RuvBI2 has a multitiude of functions that contribute to the tumorigenesis.
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0172
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0172, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0172, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Ups and Downs on the ESG Journey
Creators: name: Khan, Vina Javed
Publisher: name: University of Wollongong
Year: 2025
Subjects: classificationCode: 350201
subject: Environment and climate finance
classificationCode: 350202
subject: Finance
classificationCode: 350299
subject: Banking, finance and investment not elsewhere classified
classificationCode: 4101
subject: Climate change impacts and adaptation

description: This thesis is presented in the form of three studies addressing the impact of ESG activities on firm risk and value. Each study explores both the downside risk and upside potential of ESG activities. As part of ESG, this thesis also examines exposure by firms to the physical and transitional aspects of climate change and climate risk. The results show that ESG activities overall, and especially social activities in S&P 500 firms, reduce downside risk and upside reward, resulting in increased firm value. Examining the physical and transitional aspects of climate change exposure, the results show that increases in these forms of risk encourage environmental innovation in firms, leading to decreases in downside risk although upside rewards are limited. However, this relationship weakens when climate policy uncertainty is high. The physical risk of extreme heat events brought about by climate change leads to changes in operational performance by reducing labour productivity and increasing electricity expenses. For depreciation, the results contradict with the arguments. However, engaging in environmentally innovative activities, such as building green buildings or acquiring clean technology, counters the negative effect of extreme heat exposure for firms. The findings from this thesis provide important evidence for managers, policy makers, and governments to consider when supporting and funding green investments to maintain firm value, employment, and economic growth.
Additional file 1 of Cost-effectiveness of medical migration for chronic kidney disease: a national cross-sectional study in China
Creators: name: Ao, Yumeng
name: Yang, Chao
name: Li, Pengfei
name: Wang, Fulin
name: Peng, Suyuan
name: Wang, Huai-Yu
name: Wang, Jinwei
name: Zhao, Ming-Hui
name: Zhang, Luxia
name: Yuan, Ye
name: Qin, Xuezheng
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1.
An investigation of the neurocognitive phenotype of 22Q11.2 deletion syndrome across developmental stages.
Creators: name: Howley, Sarah A.
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Background: 22q11.2 deletion syndrome (22qDS) is a common microdeletion disorder arising from a deletion on the long (q) arm of chromosome 22. It is associated with a complex and variably expressed phenotype, which includes a range of neuroanatomical and cognitive abnormalities. The effect of general intellectual disability on the neurocognitive profile of 22qDS and the development of cognitive abilities across developmental stages requires further research. Aims: The current study aims to investigate the extent to which the neurocognitive profile of 22qDS is mediated by general intellectual impairment and to construct cross-sectional developmental trajectories of executive functions and memory abilities in children, adolescents and adults with 22qDS. Methods: Standardised cognitive test batteries were employed to assess the key areas of visual-motor function, executive function and memory in children, adolescents and adults with 22qDS. The effects of IQ were assessed using an IQ-matched control group and a statistical method for testing for differential deficits in cognitive functioning. Cross-sectional developmental trajectories were constructed to examine changes in cognitive profiles across age ranges. Results: Each age group displayed cognitive profiles characterised by preserved verbal/auditory processing and selective deficits in visual and spatial perception. Compared to IQ-matched controls, the child/adolescent group exhibited differential deficits in fine motor speed and visuospatial memory but they did not differ from IQ-matched controls on any measure of executive function. The adult group did not display any cognitive deficit in excess of their overall intellectual impairment. Visuospatial and pattern recognition memory were observed to improve significantly across the age range. Executive functions, with the exception of verbal working memory, displayed no significant improvement across the age range. Conclusions: These findings suggest that the impact of general intellectual disability on the neurocognitive phenotype of 22qDS was mediated by the developmental stage of the study participants. Fine motor ability and visuospatial recall may exhibit developmental delay relative to other cognitive abilities and pre-frontally mediated executive functions appear to exhibit atypical developmental trajectories.
A study to find novel genetic abnormalities associated with epilepsy in affected Irish families.
Creators: name: O'Connor, Gerard
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Background; Epilepsy is one of the commonest neurological illnesses. There is considerable evidence that, in many cases, epilepsy is partly or completely genetic in aetiology. However, in spite of progress in certain Mendelian epilepsy syndromes, the genetic cause of epilepsy within families often remains unclear. With the advent of techniques such as whole exome sequencing, it may now be possible to identify the novel genetic variations underlying epilepsy in affected families. The aim of this study is to use whole exome sequencing to identify novel genetic abnormalities associated with epilepsy in affected Irish families. These novel genetic abnormalities will act as candidate causal variants for further study. Methods; We sought to identify Irish families with strong histories of epilepsy. Familes were considered for inclusion if the index case, one of their first degree relatives and one other individual in the family were affected by epilepsy. In each family identified, we clinically phenotyped individuals who were affected and unaffected by epilepsy syndromes. From each participant, we obtained a tissue sample (blood or saliva) for DNA analysis. In a number o f selected families, we performed genetic analysis using whole exome sequencing looking for novel genetic variations which could be the cause of epilepsy in these families. Results; We identified 96 families who met the criteria for inclusion on initial assessment, of whom 11 were recruited, representing a total of 110 individuals. There was considerable variability of phenotypes within the families identified. Affected individuals from four families had whole exome sequencing, with one other family having candidate gene analysis based on the results of previous screening of a family member. We identified novel genetic variations which could be candidates for further study as a possible cause for the epilepsy syndromes seen in three of the five families analysed. In one family, we identified a novel variation in a known epilepsy gene (A348Y in the SLC2A1 gene). In two other families, novel mutations were identified in genes not previously demonstrated to be associated with epilepsy (CHRNB3 and NARG2) Conclusion; Our study demonstrates that whole exome sequencing can be used to characterise novel genetic variations in Irish families with a strong history of epilepsy. Further studies are necessary to demonstrate that these abnormalities are causal for the epilepsy syndromes seen.
Guidelines Towards Better Participation of Older Adults in Software Development Processes using a new SPIRAL Method and Participatory Approach
Creators: name: Kopeć, Wiesław
name: Nielek, Radosław
name: Wierzbicki, Adam
Publisher: name: arXiv
Year: 2018
Subjects: subject: Software Engineering (cs.SE)
subject: Computers and Society (cs.CY)
subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: This paper presents a new method of engaging older participants in the process of application and IT solutions development for older adults for emerging IT and tech startups. A new method called SPIRAL (Support for Participant Involvement in Rapid and Agile software development Labs) is proposed which adds both sustainability and flexibility to the development process with older adults. This method is based on the participatory approach and user empowerment of older adults with the aid of a bootstrapped Living Lab concept and it goes beyond well established user-centered and empathic design. SPIRAL provides strategies for direct involvement of older participants in the software development processes from the very early stage to support the agile approach with rapid prototyping, in particular in new and emerging startup environments with limited capabilities, including time, team and resources.
Announcement of the Summer Session Supplement to Calendar 1968-68 Fiftieth Session: July 2 to August 15, 1969
Creators: name: University Of British Columbia
Publisher: name: Vancouver : University of British Columbia
Year: 2017

description: Announcement of courses for the 50th summer session at the University of British Columbia, taking place from July 2nd to August 15th, 1969. Contains course schedule, course descriptions and details, fees, and other information about the session.
Newborn Heart Study - Novel Echocardiographic and Biomarker Measurements in Health & Disease
Creators: name: Armstrong, Kathryn
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Neonatal myocardial dysfunction may impact negatively on survival outcomes in preterm and term infants. Early identification and subsequent intervention may improve outcomes in preterm infants and term infants following a hypoxic ischaemic injury. Current echocardiographic measures for assessing Left Ventricular systolic and diastolic function have limitations in preterm infants. Newer techniques such as tissue Doppler Imaging (TDI) and Speckle Tracking Imaging (STI) provide a global assessment of myocardial systolic and diastolic function and have been introduced in adult cardiology. However there is a paucity of data on these modalities in children and neonates. Cardiac biomarkers, Troponin T and NT pro BNP reflect myocardial dysfunction and are elevated in preterm infant with a Patent Ductus Arteriosus and in term infants with neonatal encephalopathy. Sixty healthy term control infants were recruited who underwent echocardiography on Day 2-4 of life. Normal data for Left and Right ventricular diastolic velocities were obtained using Tissue Doppler Imaging. A further 20 healthy term infants underwent echocardiography for longitudinal strain analysis using Speckle Tracking Imaging. Infants < 32 weeks or < 1500kg underwent serial echocardiography to compare measures of shortening and ejection fraction with Tissue Doppler velocities. There was a significant increase in the RV systolic and diastolic velocities over the first week of life. There was a significant increase in the LV diastolic velocities over the first week of life. There was no significant increase in either LV shortening or ejection fraction over the first week of life. Tissue Doppler velocities were significantly lower SUMMARY OF THESIS XI over the first week of life in infants who developed Chronic Lung Disease, Necrotising Enterocolitis and in those infants who required surgical PDA ligation. Vitamin D levels were low in preterm infants enrolled in the study, and Tissue Doppler systolic and diastolic velocities were significantly lower in preterm infants compared to term infants on Day one of life. Our final part of the study was the validation of the Cobas h232 Point of Care Analyser for analysis of Troponin T and NT pro BNP. We found that the Cobas h232 had correlation with the gold standard laboratory Roche 800 analyser. In conclusion serial echocardiography in the NICU may improve outcomes in preterm infants by allowing early therapeutic intervention. Analysis of Troponin T and NT pro BNP at the bedside in conjunction with echocardiography may aid in the diagnosis of myocardial dysfunction, more timely therapy and ultimately improve survival and neurodevelopmental outcomes in preterm infant and in those with Neonatal Encephalopathy.
Announcement of the Summer Session Supplement to Calendar 1969-70 Fifty-first Session: July 6 to August 21, 1970
Creators: name: University Of British Columbia
Publisher: name: Vancouver : University of British Columbia
Year: 2017

description: Announcement of courses for the 51st summer session at the University of British Columbia, taking place from July 6th to August 21st, 1970. Contains course schedule, course descriptions and details, fees, and other information about the session.
Prenylated flavonoids and dihydrophenanthrenes from the leaves of Epimedium brevicornu and their cytotoxicity against HepG2 cells
Creators: name: Pang, Xu
name: Yin, Shuang-Shuang
name: Yu, Hai-Yang
name: Zhang, Yi
name: Wang, Tao
name: Hu, Li-Min
name: Han, Li-Feng
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Phytochemical study on the leaves of Epimedium brevicornu finally led to the isolation of four prenylated flavonoids (1–4) and three dihydrophenanthrenes (5–7), of which 1, 2, 5 and 7 were new compounds. The structures of these compounds were established mainly by spectroscopic techniques, including NMR spectroscopy and mass spectrometry. These isolates exhibited the cytotoxic activities against HepG2 cells with the IC50 values of 32.8–87.3 μM.
Elastic distance between curves under the metamorphosis viewpoint
Creators: name: Younes, Laurent
Publisher: name: arXiv
Year: 2018
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We provide a new angle and obtain new results on a class of metrics on length-normalized curves in $d$ dimensions, represented by their unit tangents expressed as a function of arc-length, which are functions from the unit interval to the $(d-1)$-dimensional unit sphere. These metrics are derived from the combined action of diffeomorphisms (change of parameters) and arc-length-dependent rotation acting on the tangent. Minimizing a Riemannian metric balancing a right-invariant metric on diffeomorphisms and an $L^2$ norm on the motion of tangents leads to a special case of "metamorphosis", which provides a general framework adapted to similar situations when Lie groups acts on Riemannian manifolds. Within this framework and using a Sobolev norm with order 1 on the diffeomorphism group, we generalize previous results from the literature that provide explicit geodesic distances on parametrized curves.
Additional file 1: of Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control
Creators: name: MartĂ­Nez-Lumbreras, Santiago
name: Krysztofinska, Ewelina
name: Thapaliya, Arjun
name: Spilotros, Alessandro
name: Matak-Vinkovic, Dijana
name: Salvadori, Enrico
name: Roboti, Peristera
name: Nyathi, Yvonne
name: Muench, Janina
name: Roessler, Maxie
name: Svergun, Dmitri
name: High, Stephen
name: Isaacson, Rivka
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Figure S1. Sequence alignment of human SGTA (Homo sapiens) and several homolog proteins: Sumatran orangutan (Pongo abelii), white-cheeked gibbon (Nomascus leucogenys), dog (Cannis lupus familiaris), pig (Sus scrofa), rat (Rattus norvegicus), chicken (Gallus gallus), African clawed frog (Xenopus laevis), gray short-tailed opossum (Monodelphis domestica), three-spined stickleback (Gasterosteus aculeatus), Japanese pufferfish (Takifugu rubripes), American chameleon (Anolis carolinensis), Spotted green pufferfish (Tetraodon nigroviridis), Japanese rice fish (Oryzias latipes), and West Indian ocean coelacanth (Latimeria chalumnae). All proteins were selected using the BLAST tool with the hsSGTA sequence as query; the alignment was obtained using Jalview 2.7. (PDF 1115 kb)
Degeneracy between nonadiabatic dark energy models and $Λ$CDM: ISW effect and the cross correlation of CMB with galaxy clustering data
Creators: name: Velten, Hermano
name: Fazolo, Raquel Emy
name: von Marttens, Rodrigo
name: Gomes, Syrios
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: As recently pointed out in Ref. [Phys.\ Rev.\ D {\bf 96}, 8, 083502 (2017)] the evolution of the linear matter perturbations in nonadiabatic dynamical dark energy models is almost indistinguishable (quasi-degenerated) to the standard $Λ$CDM scenario. In this work we extend this analysis to CMB observables in particular the integrated Sachs-Wolfe effect and its cross-correlation with large scale structure. We find that this feature persists for such CMB related observable reinforcing that new probes and analysis are necessary to reveal the nonadiabatic features in the dark energy sector.
description: 9 pages, 8 figures
The Glue Content of the Pion
Creators: name: Meyer, Harvey B.
name: Negele, John W.
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We perform a quenched computation of the glue momentum fraction in the pion. Different discretizations of the gluonic energy-momentum tensor are studied on the lattice for that purpose. We discuss some implications based on the momentum sum rule. Finally we point out promising applications of the techniques developed here.
description: 7 pages, 2 figures, 2 tables; Proceedings of LATTICE07
Optimising glucocorticoid replacement therapy in severely adrenocorticoptropin deficient hypopituitary males.
Creators: name: Lucy-Ann Behan
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Inappropriate cortisol replacement has been proposed as a contributing factor in the increased morbidity and mortality associated with hypopituitarism. The aim of this study is to examine the effect of three commonly prescribed hydrocortisone replacement regimens on predefined metabolic end points and quality of life (QoL) in male subjects with severe adrenocorticotropin (ACTH) deficiency with a view to identifying the most physiologic regimen. 10 hypopituitary men participated in a prospective, randomised, crossover, open protocol of 6 weeks on each of the following regimens: Dose A (20mg AM, 10mg PM), Dose B (10mg AM, 10mg PM), Dose C (10mg AM, 5mg PM). Results were compared between dose regimens and to healthy control subjects. The lowest dose regimen, dose C (10mg/5mg), was associated with a 24 hour serum cortisol profile that most closely approximated that of the control subjects, without any difference in QoL between doses. There were significant increases in serum markers of bone formation in the lower dose regimen dose C, with an 86% increase in procollagen type I N-propeptide (PINP), and a 56% increase in intact osteocalcin (OC[1-49]) compared to dose A, without concurrent increases in bone resorption markers. These findings reflect a more positive bone remodelling balance in the lowest dose regimen, resulting in net bone gain. Tissue exposure to cortisol was assessed by examining 24hour urinary cortisol metabolites. Dose A (20mg/10mg) was associated with significantly higher total cortisol metabolites compared to the two other dose regimens and compared to healthy controls. We also demonstrated increased tissue cortisol exposure across all dose regimens compared to healthy controls; however it was highest with dose A. There was no difference between dose regimens or compared to controls in glucose or insulin metabolism or in 24 hour blood pressure. Dose C (10mg/5mg) was associated with a reduction in the ambulatory arterial stiffness index (AASI) and a more physiological nocturnal blood pressure dip which may indicate a more favourable vascular status. This study demonstrates a lower dose hydrocortisone replacement regimen in severe ACTH deficiency is associated with a more favourable metabolic profile without adversely affecting QoL. These findings suggest that physicians may safely aim for a reduction in prescribed hydrocortisone replacement doses.
Homolodromia kai Guinot 1993
Creators: name: Ahyong, Shane T.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Homolodromiidae
Homolodromia
Homolodromia kai

description: Homolodromia kai Guinot, 1993 (Fig. 1B) Homolodromia kai Guinot, 1993: 1228, fig. 5 [type locality: Kai Islands, Indonesia]; 1995: 197–200, fig. 5B, 9a–d, 10A– D. — Ng & Ho 1999: 1123–1125, fig. 1. — Dawson 2002: 6–12, figs 1c, 2, pls 1–3. — Poore 2004: 311, fig. 89e. Material examined. Mahina Knoll: NIWA 6761, 1 female (cl 19.9 mm, cw 14.6 mm), 37°21.74–21.40'S, 177°06.63'E, 632– 458 m, TAN0413/136, 14 Nov 2004. Eastern Australia: AM P60914, 1 female (cl 36.1 mm), E of Port Stephens, New South Wales, 32°49'S, 152°47'E, 935 m, K88-21-02, 3 Dec 1988. Remarks. The present specimen is the second to be recorded from New Zealand, with the first also from the Bay of Plenty at a depth of 350–382 m (Dawson 2002). Homolodromia kai is one of three known New Zealand homolodromiids. The two others, Dicranodromia delli sp. nov. and D. spinulata Guinot, 1995, can be distinguished from H. kai by their the subcheliform rather than cheliform P4–5 (compare Fig. 1C, 2A, 4D), and proportionally shorter P2–3 dactyli, being markedly shorter, rather than as long as than their respective propodi (Fig. 1C, 3D). Poore's (2004) record of H. kai from southeastern Australia is based on a 36.1 mm female (AM P60914), the largest and deepest known specimen of the species. Distribution. Indonesia, the South China Sea, Vanuatu, New Caledonia, southeastern Australia and northeastern New Zealand; 350– 935 m.
description: Published as part of Ahyong, Shane T., 2008, Deepwater crabs from seamounts and chemosynthetic habitats off eastern New Zealand (Crustacea: Decapoda: Brachyura), pp. 1-72 in Zootaxa 1708 (1) on page 11, DOI: 10.11646/zootaxa.1708.1.1, http://zenodo.org/record/5107434
description: {"references": ["Guinot, D. (1993) Donnees nouvelles sur les Crabes primitives (Crustacea Decapoda Brachyura Podotremata). Comptes Rendus des Seances de l'Academie des Sciences, Paris, (III), 326 (11), 1225 - 1232.", "Ho, P. - H. & Ng, P. K. L. (1999) On Homolodromia kai Guinot, 1993 (Decapoda, Brachyura, Homolodromiidae) from the South China Sea. Crustaceana, 72 (9), 1123 - 1125.", "Dawson, E. W. (2002) First record of the primitive crab Homolodromia in New Zealand waters (Crustacea, Decapoda, Brachyura, Homolodromiidae), with a provisional new key to the extant species of Homolodromia. Hutton Foundation New Zealand, Special Papers, 1, 1 - 21.", "Poore, G. C. B. (2004) Marine Decapod Crustacea of Southern Australia: a guide to identification. Melbourne: CSIRO Publishing. 574 pp."]}
Scatterer assisted whispering gallery mode microprobe
Creators: name: Shu, Fangjie
name: Jiang, Xuefeng
name: Zhao, Guangming
name: Yang, Lan
Publisher: name: arXiv
Year: 2018
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Fiber based whispering-gallery-mode (WGM) microprobe, combining both the high optical field enhancement of the WGMs and the practicability of the fiber probe, is highly demanded in sensing and imaging. Here in this paper, we experimentally report the efficient far-field coupling of WGMs by scattering the focused laser beam through a nanotip. With the help of Purcell effect as well as the two-step focusing technique, a WGM excitation efficiency as high as 16.8% has been achieved. Both the input and output of the probe light propagate along the same fiber, which makes the whole coupling system a fiber based WGM microprobe for sensing/imaging applications.
Additional file 1 of Genome-wide identification of CNGC genes in Chinese jujube (Ziziphus jujuba Mill.) and ZjCNGC2 mediated signalling cascades in response to cold stress
Creators: name: Wang, Lixin
name: Li, Min
name: Liu, Zhiguo
name: Dai, Li
name: Zhang, Mengling
name: Wang, Lili
name: Zhao, Jin
name: Liu, Mengjun
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file S1. The protein sequences of the CNGC genes from Ziziphus jujuba Mill.
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 204
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 204, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 204, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Comparison of Dynamical Approximation Schemes for Non-Linear Gravitational Clustering
Creators: name: Melott, Adrian L.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: I report on controlled comparison of gravitational approximation schemes linear/lognormal/adhesion/frozen-flow/Zel'dovich(ZA) and ZA's second--order generalization. In the last two cases we also created new versions of the approximation by truncation, i.e., by finding an optimum smoothing window (see text) for the initial conditions. The Zel'dovich approximation, with optimized initial smoothing, worked extremely well. Its second-order generalization was slightly better. The success of our best-choice was a result of the treatment of the phases of nonlinear Fourier components. The adhesion approximation produced the most accurate nonlinear power spectrum and density distribution, but its phase errors suggest mass condensations were moved somewhat incorrectly. Due to its better reproduction of the mass density distribution function and power spectrum, adhesion might be preferred for some uses. We recommend either n-body simulations or our modified versions of ZA, depending on the purpose. Modified ZA can rapidly generate large numbers of realizations of model universes with good accuracy down to galaxy group (or smaller) mass scales.
description: 8 pp., plain TeX. ApJ Letters, in press. Contact melott@kusmos.phsx.ukans.edu for Figures
Announcement of the Summer Session Supplement to Calendar 1973/74 Fifty-fifth Session: July 2 to August 10, 1974
Creators: name: University Of British Columbia
Publisher: name: Vancouver : University of British Columbia
Year: 2017

description: Announcement of courses for the 55th summer session at the University of British Columbia, taking place from July 2nd to August 10th, 1974. Contains course schedule, course descriptions and details, fees, and other information about the session.
A non-autonomous scalar one-dimensional dissipative parabolic problem: The description of the dynamics
Creators: name: Broche, Rita de Cássia D. S.
name: Carvalho, Alexandre N.
name: Valero, José
Publisher: name: arXiv
Year: 2018
Subjects: subject: Dynamical Systems (math.DS)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35K91 (35B32 35B41 37L30)

description: The purpose of this paper is to give a characterization of the structure of non-autonomous attractors of the problem $u_t= u_{xx} + λu - β(t)u^3$ when the parameter $λ> 0$ varies. Also, we answer a question proposed in [11], concerning the complete description of the structure of the pullback attractor of the problem when $1
description: 32 pages, 04 figures
Quantum Logic and the Histories Approach to Quantum Theory
Creators: name: Isham, C. J.
Publisher: name: arXiv
Year: 1993
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: An extended analysis is made of the Gell-Mann and Hartle axioms for a generalised `histories' approach to quantum theory. Emphasis is placed on finding equivalents of the lattice structure that is employed in standard quantum logic. Particular attention is given to `quasi-temporal' theories in which the notion of time-evolution is less rigid than in conventional Hamiltonian physics; theories of this type are expected to arise naturally in the context of quantum gravity and quantum field theory in a curved space-time. The quasi-temporal structure is coded in a partial semi-group of `temporal supports' that underpins the lattice of history propositions. Non-trivial examples include quantum field theory on a non globally-hyperbolic spacetime, and a simple cobordism approach to a theory of quantum topology. It is shown how the set of history propositions in standard quantum theory can be realised in such a way that each history proposition is represented by a genuine projection operator. This provides valuable insight into the possible lattice structure in general history theories, and also provides a number of potential models for theories of this type.
description: TP/92-93/39 36 pages + one page of diagrams (I could email Apple laser printer postscript file for anyone who is especially keen)
Apache Calcite: A Foundational Framework for Optimized Query Processing Over Heterogeneous Data Sources
Creators: name: Begoli, Edmon
name: Rodríguez, Jesús Camacho
name: Hyde, Julian
name: Mior, Michael J.
name: Lemire, Daniel
Publisher: name: arXiv
Year: 2018
Subjects: subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: Apache Calcite is a foundational software framework that provides query processing, optimization, and query language support to many popular open-source data processing systems such as Apache Hive, Apache Storm, Apache Flink, Druid, and MapD. Calcite's architecture consists of a modular and extensible query optimizer with hundreds of built-in optimization rules, a query processor capable of processing a variety of query languages, an adapter architecture designed for extensibility, and support for heterogeneous data models and stores (relational, semi-structured, streaming, and geospatial). This flexible, embeddable, and extensible architecture is what makes Calcite an attractive choice for adoption in big-data frameworks. It is an active project that continues to introduce support for the new types of data sources, query languages, and approaches to query processing and optimization.
description: SIGMOD'18
Addressing the notion of trust around ChatGPT in the high-stakes use case of insurance
Creators: name: Ressel, Juliane
name: Voller, Michaele
name: Murphy, Finbarr
name: Mullins, Martin
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 3503
subject: Business systems in context

description: The public discourse concerning the level of (dis)trust in ChatGPT and other applications based on large language models (LLMs) is loaded with generic, dread risk terms, while the heterogeneity of relevant theoretical concepts and empirical measurements of trust further impedes in-depth analysis. Thus, a more nuanced understanding of the factors driving the trust judgment call is essential to avoid unwarranted trust. In this commentary paper, we propose that addressing the notion of trust in consumer-facing LLM-based systems across the insurance industry can confer enhanced specificity to this debate. The concept and role of trust are germane to this particular setting due to the highly intangible nature of the product coupled with elevated levels of risk, complexity, and information asymmetry. Moreover, widespread use of LLMs in this sector is to be expected, given the vast array of text documents, particularly general policy conditions or claims protocols. Insurance as a practice is highly relevant to the welfare of citizens and has numerous spillover effects on wider public policy areas. We therefore argue that a domain-specific approach to good AI governance is essential to avoid negative externalities around financial inclusion. Indeed, as a constitutive element of trust, vulnerability is particularly challenging within this high-stakes set of transactions, with the adoption of LLMs adding to the socio-ethical risks. In light of this, our commentary provides a valuable baseline to support regulators and policymakers in unravelling the profound socioeconomic consequences that may arise from adopting consumer-facing LLMs in insurance.
The essential dimension of low dimensional tori via lattices
Creators: name: Case, Gareth
Publisher: name: Lancaster University
Year: 2019

description: The essential dimension, ed_k(G), of an algebraic group G is an invariant that measures the complexity of G-torsors over fields. The correspondence between algebraic tori and finite subgroups of GL_n(Z) means one can establish bounds on ed_k(T) of an algebraic torus T by studying the action of the corresponding subgroup of GL_n(Z).
title: Epistemic practices in social work
title: hear me out
titleType: Subtitle
Creators: name: Kelly, Emma
Publisher: name: Lancaster University
Year: 2019
Subjects: knowledges
social work
sexual abuse

description: This PhD by publication explores how ‘knowledges’ in social work research are authorized often to those who use and provide services. It draws together 11 publications, which are a mixture of sole and co authored peer reviewed journal articles, book chapters, and co authored publications for a range of charitable and public bodies both within the UK and Europe. The concept of ‘epistemic injustice’, is used to examine the connections between my published works. Stemming from the tradition of feminist philosophy, epistemic injustice is when the capacity to hear another’s testimony is diminished. With its focus on the interrelationship between hearing and being heard, epistemic justice has an under utilised value in social work practice and research. Building on the central themes of voice and justice, I argue that the discrediting of an individual testimony leads to individual and collective harm, as the opportunities for some to contribute to the common store of social meanings are diminished, including asylum seeking young people, victim and survivors of child sexual exploitation, child sexual abuse and child trafficking. My published works are examined as case studies to consider which and whose knowledge is taken seriously and why. I considers the harms done through the process of being discredited; both to the individual (their testimony and their identity –as sense of self is shaped by these negative associations) and to a developing knowledge (as accounts are missed and the potential growth of connections (be they defeating, justifying or inferential) is lost. Although all knowledge is partial and co-produced, I consider the obligation to make relevant efforts to understand how the world looks from different points of view, especially those who use and provide services.
Two-Stream Binocular Network: Accurate Near Field Finger Detection Based On Binocular Images
Creators: name: Wei, Yi
name: Wang, Guijin
name: Zhang, Cairong
name: Guo, Hengkai
name: Chen, Xinghao
name: Yang, Huazhong
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Fingertip detection plays an important role in human computer interaction. Previous works transform binocular images into depth images. Then depth-based hand pose estimation methods are used to predict 3D positions of fingertips. Different from previous works, we propose a new framework, named Two-Stream Binocular Network (TSBnet) to detect fingertips from binocular images directly. TSBnet first shares convolutional layers for low level features of right and left images. Then it extracts high level features in two-stream convolutional networks separately. Further, we add a new layer: binocular distance measurement layer to improve performance of our model. To verify our scheme, we build a binocular hand image dataset, containing about 117k pairs of images in training set and 10k pairs of images in test set. Our methods achieve an average error of 10.9mm on our test set, outperforming previous work by 5.9mm (relatively 35.1%).
description: Published in: Visual Communications and Image Processing (VCIP), 2017 IEEE. Original IEEE publication available on https://ieeexplore.ieee.org/abstract/document/8305146/. Dataset available on https://sites.google.com/view/thuhand17
Additional file 15: of Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control
Creators: name: MartĂ­Nez-Lumbreras, Santiago
name: Krysztofinska, Ewelina
name: Thapaliya, Arjun
name: Spilotros, Alessandro
name: Matak-Vinkovic, Dijana
name: Salvadori, Enrico
name: Roboti, Peristera
name: Nyathi, Yvonne
name: Muench, Janina
name: Roessler, Maxie
name: Svergun, Dmitri
name: High, Stephen
name: Isaacson, Rivka
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Figure S14. DEER measurements and distances determined for FL and NT-TPR SGTA constructs spin-labeled in the four SGTA mutants. (i) Primary frequency-domain DEER data. (ii) Background-corrected dipolar evolution data (black lines) and corresponding fits obtained through DeerAnalysis2016 [49] by Tikhonov regularization. (iii) Distance distributions obtained by Tikhonov regularization. Blue fits: FL SGTA; red fits: NT-TPR construct. (PDF 3125 kb)