cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Using artificial neural networks for taxonomic classification of viral sequences
Creators: name: Kohls, Moritz
name: Kircher, Magdalena
name: Krepel, Jessica
name: Liebig, Pamela
name: Jung, Klaus
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: deep learning
subject: neural network
subject: taxonomy classification
subject: viral metagenomics
subject: virus discovery
subject: 610 Medical sciences; Medicine

description: Background: Next-generation sequencing of biological samples from infected hosts is frequently used to identify specific viruses that might be causative for a disease. For that purpose, sequencing reads are usually mapped against a database of known viral reference genomes ([ref:1]; e.g. fasta[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Διερεύνηση αλληλεπίδρασης χρηστών ποδηλάτου και οδηγών:
Creators: name: Προδρόμου, Μιχάλης Χρήστου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Διερεύνηση αλληλεπίδρασης
Ποδηλατιστής - Αυτοκίνητο
Ενταξη ποδηλάτου
Investigation of the interaction
Cyclists - drivers
Introduction of bicycles

description: Η παρούσα Διπλωματική Εργασία, έχει ως σκοπό να διερευνήσει το βαθμό της αλληλεπίδρασης των ποδηλατιστών με τους οδηγούς και ταυτόχρονα να παρουσιάσει τους κατάλληλους τρόπους ένταξης του ποδηλάτου, ως εναλλακτικό μέσο μετακίνησης στο αστικό περιβάλλον και τον ορθό σχεδιασμό του οδικού δικτύου με γνώμονα την δυνατότητα να υπάρξει μια ομαλή ένταξη του ποδηλάτου στο υπάρχον δίκτυο. Συγκεκριμένα έγινε μια προσπάθεια προσδιορισμού του βαθμού αλληλεπίδρασης μεταξύ των ποδηλατιστών και των οδηγών, της περιγραφής των μορφών των “περιστατικών” εμπλοκής μεταξύ τους που συναντώνται στο οδικό δίκτυο καθώς και της κατανόησης της συμπεριφοράς του μέσου χρήστη ποδηλάτου. Μέσω της ανασκόπησης της διεθνούς και ελληνικής βιβλιογραφίας, επιχειρήθηκε η διερεύνηση θεμάτων που αφορούν στην ένταξη του ποδηλάτου στον αστικό χώρο, στην αλληλεπίδραση ποδηλάτη και οδηγού αυτοκινήτου καθώς και θεμάτων που άπτονται της ψυχολογίας του ποδηλάτη. Ακολούθησε η εκπόνηση έρευνας ερωτηματολογίου και η ανάλυση των στοιχείων που συλλέχτηκαν. Τέλος, διαμορφώθηκαν προτάσεις με βάση τα αποτελέσματα της ανάλυσης, ώστε να υποβοηθηθεί η διαδικασία που αφορά στην ένταξη του ποδηλάτου στο οδικό δίκτυο της πόλης.
description: The objective of the present Master Thesis is the investigation of the interaction between cyclists and drivers and at the same time the presentation of the most appropriate ways for the introduction of the bicycle, as an alternative mean of transport in the urban environment. More specifically an attempt has been made in order to investigate issues concerning the introduction of bicycles in the urban environment, the interaction between cyclists and drivers and the psychology of the cyclists. Initially, this attempt is based on the study of the international and national literature in the specific scientific fields. Then a questionnaire – based survey took place followed by the data analysis. Finally, based on the analysis results, proposals are made in order to support the process concerning the effective introduction of bicycles in the city road network
title: Preprocessing of direct infusion high resolution mass spectrometry data from metabolomics studies
Creators: name: Szymczak, Silke
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: metabolomics
subject: mass spectrometry
subject: preprocessing
subject: annotation
subject: 610 Medical sciences; Medicine

description: The focus of metabolomics studies are the end products of cellular processes that provide a snapshot of the physiological state in a cell, tissue, or organism. Direct infusion methods coupled with high resolution mass analyzers avoid chromatography based separation of samples. However, preprocessing[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
title: NetCoMi: Network Construction and Comparison for Microbiome Data
Creators: name: Peschel, Stefanie
name: Müller, Christian L.
name: von Mutius, Erika
name: Boulesteix, Anne-Laure
name: Depner, Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: differential network analysis
subject: sequencing data
subject: microbiome
subject: 610 Medical sciences; Medicine

description: Background: Network analysis methods are suitable for investigating the microbial interplay within a habitat. Since microbial associations may change between conditions, e.g. between health and disease state, comparing microbial association networks between two groups might be useful. Two approaches[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Η υλοποίηση του ενιαίου και ευφυούς συστήματος κομίστρου στη Θεσσαλονίκη:
Creators: name: Κοιλανίτης, Θεόδωρος Χρήστου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: ενιαίο και ευφυές σύστημα
δημόσια σύμβαση προμήθειας
σύμπραξη δημοσίου ιδιωτικού τομέα
smart ticketing system
public supply contract
public private partnership

description: Αποτελεί αδιαμφισβήτητο γεγονός ότι οι δημόσιες συγκοινωνίες αποτελούν βασικό πυλώνα κάθε σύγχρονης κοινωνίας για την επίτευξη του στόχου της βελτίωσης της ποιότητας ζωής των πολιτών της. Τα πλεονεκτήματα που προκύπτουν από τη χρήση τους είναι πολλά, τόσο για τους φορείς των αστικών συγκοινωνιών, όσο και για τους πολίτες. Οι Δημόσιες Αστικές Συγκοινωνίες στη Θεσσαλονίκη αποτελούν μια ενδιαφέρουσα περίπτωση μελέτης, καθώς αναμένεται να αλλάξουν ριζικά μέσα στα επόμενα χρόνια, με την λειτουργία του μετρό, και των σχεδιαζόμενων θαλάσσιων συγκοινωνιών και του τραμ. Έτσι, η εφαρμογή των πλέον σύγχρονων τεχνολογιών για την είσπραξη του ανάλογου αντιτίμου ενδείκνυται για πολλούς λόγους. Στα επόμενα κεφάλαια της διπλωματικής παρουσιάζονται αρχικά βασικά στοιχεία για τις αστικές συγκοινωνίες της Θεσσαλονίκης, στη συνέχεια γίνεται αναφορά στα ενιαία και ευφυή συστήματα γενικότερα και ακολούθως, παρουσιάζονται διάφορες προσεγγίσεις που μπορεί να ακολουθήσει το Συμβούλιο Αστικών Συγκοινωνιών Θεσσαλονίκης από την πλευρά των συμβάσεων, αφού πρώτα μελετηθούν οι επιπτώσεις του τύπου σύμβασης στην έκβαση ενός έργου γενικά. Οι περιπτώσεις που εξετάζονται είναι η δημόσια σύμβαση προμήθειας, η σύμπραξη δημοσίου & ιδιωτικού τομέα και στη συνέχεια δίνεται βάρος στην καινοτομία γενικότερα αλλά και στις προ-εμπορικές συμβάσεις ως εργαλείο προώθησή της. Ακόμα εξετάζεται η δυνατότητα εφαρμογής των προ-εμπορικών συμβάσεων στην περίπτωση της Θεσσαλονίκης
description: It is an undoubted fact that public transport, comprises a fundamental pillar in any contemporary society, in order to attain the goal of ameliorating people’s quality of life. Numerous advantages emerge from their use, both for the public transport authorities and the citizens as well. Public transport in the city of Thessaloniki constitutes an interesting case study, as they are about to change radically in the upcoming years due to the subway which is under construction and other means of transport which are being planned. Thus, the implementation of new technologies in the ticketing system is indicated for many reasons. In the next chapters of this thesis, we present the basic facts regarding public transport in Thessaloniki and then we describe the smart ticketing systems. Afterwards, we examine the impact of the procurement type on the project’s outcome and then, we present the alternative procurement types regarding Thessaloniki’s smart ticketing system. Particularly, we examine the cases of public supply contract, of Public Private Partnership and then we analyze innovation, in general, and the role pre-commercial procurement can play in fostering innovation. Then, we examine the possibility of implementation of a pre-commercial procurement in Thessaloniki’s ticketing system.
title: Polygenic Risk Score Approaches for Methylation Data in Multi-Ethnic Populations
Creators: name: Huels, Anke
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: epigenetics
subject: polygenic risk scores
subject: genetic epidemiology
subject: 610 Medical sciences; Medicine

description: Polygenic approaches often access more variance of complex traits than is possible by single variant approaches. For genotype data, polygenic risk scores (PRS) are widely used for risk prediction as well as in association and interaction studies. Recently, interest has been growing in transferring PRS[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
The Complex Structure of the Cl 1604 Supercluster at z~0.9
Creators: name: Gal, R. R.
name: Lemaux, B. C.
name: Lubin, L. M.
name: Kocevski, D.
name: Squires, G. K.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Cl1604 supercluster at z=0.9 is one of a small handful of such structures discovered in the high redshift universe, and is the first target observed as part of the Observations of Redshift Evolution in Large Scale Environments (ORELSE) Survey. To date, Cl1604 is the largest structure mapped at z~1, with the most constituent clusters and the largest number of spectroscopically confirmed member galaxies. In this paper we present the results of a spectroscopic campaign to create a three-dimensional map of Cl1604 and to understand the contamination by fore- and background large scale structures. Combining new Deep Imaging Multi-object Spectrograph observations with previous data yields redshifts for 1,383 extragalactic objects in a ~ 0.08 sq. deg region, 449 of which are supercluster members. We examine the complex three dimensional structure of Cl1604, providing velocity dispersions for eight of the member clusters and groups. Our extensive spectroscopic dataset is used to examine potential biases in cluster velocity dispersion measurements in the presence of overlapping structures and filaments. We also discuss other structures found along the line-of-sight, including a filament at z=0.6 and two serendipitously discovered clusters/groups at z~1.2.
description: Final version, appearing in ApJ
Plan de marketing para la empresa Grupo Águila Descalza
Creators: name: Cortes Díaz, Daniela Margarita
name: Botero Giraldo, Lady Johana
name: Silva Abello, Diana Marcela
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Mercadeo - Estudios de caso
subject: Servicio al cliente - Aspectos socieconómicos
subject: Organización - Aspectos sociales
subject: Indicadores
subject: Objetivos corporativos
subject: Productos merch
subject: Buyer persona
subject: Nuevas plazas

description: resultados derivados del diagnóstico empresarial realizado mediante la metodología MIME (Portfolio), que abarcó la evaluación de los ámbitos de innovación, producción, estrategia y mercadeo actuales de la compañía. Además, se tomaron en consideración los hallazgos del análisis externo del sector económico pertinente y los resultados de una encuesta aplicada a 519 residentes de los estratos 3, 4, 5 y 6 en la ciudad de Bogotá. Se pudo identificar que la empresa exhibe fortalezas y oportunidades de mejora frente a factores externos (gobierno, economía, social, sectorial y tecnológico), así como en el ámbito interno de producción y servicios. No obstante, se detectaron debilidades menores en los aspectos de innovación, dirección estratégica, mercadeo y ventas. El plan de marketing propuesto se centra en la implementación de cinco estrategias dirigidas a los subprocesos de marketing de producto, mercado, precio, atención al cliente, marca y comunicación con el objetivo de lograr resultados a corto plazo (1 año), tales como el incremento del 15% en las ventas durante el año 2024, el aumento de la productividad en mínimo 5 puntos porcentuales respecto al año anterior, y elevar el reconocimiento en el nicho objetivo de Bogotá del 23.1% al 40% o más.
description: This document presents the marketing plan for the Águila Descalza Group, based on the results derived from the business diagnosis carried out using the MIME (Portfolio) methodology, which included the evaluation of the company's current innovation, production, strategy and marketing areas. In addition, the findings of the external analysis of the relevant economic sector and the results of a survey applied to 519 residents of strata 3, 4, 5 and 6 in the city of Bogotá were taken into consideration. It was found that the company has strengths and opportunities for improvement in relation to external factors (government, economic, social, sectoral and technological), as well as internal production and services. However, minor weaknesses were detected in the areas of innovation, strategic management, marketing and sales. The proposed marketing plan focuses on the implementation of five strategies aimed at the marketing sub-processes of product, market, price, customer service, brand and communication with the objective of achieving short-term results (1 year), such as a 15% increase in sales during the year 2024, increasing productivity by at least 5 percentage points over the previous year, and raising recognition in the target niche of Bogota from 23.1% to 40% or more.
title: What is the influence of metabolic profiles on drug safety in routine care in Germany? – Findings from the EMPAR study
Creators: name: Heß, Steffen
name: Steffens, Michael
name: Fracowiak, Jochen
name: Hübner, Tatjana
name: Langner, Daria
name: Garling, Marco
name: Falkenberg, Felix
name: Röthlein, Christoph
name: Gomm, Willy
name: Linder, Roland
name: Stingl, Julia
name: Hänisch, Britta
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: drug safety
subject: pharmacogenomics
subject: pharmacoepidemiology
subject: 610 Medical sciences; Medicine

description: Background: The occurrence of adverse drug reactions (ADRs) and the individual response to drug treatment can be affected by genetic variability in metabolic profiles. The magnitude of this effect is largely unknown within a real world setting and needs to be determined in order to assess the clinical[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Encoding Frequency Constraints in Preventive Unit Commitment Using Deep Learning with Region-of-Interest Active Sampling
Creators: name: Zhang, Yichen
name: Cui, Hantao
name: Liu, Jianzhe
name: Qiu, Feng
name: Hong, Tianqi
name: Yao, Rui
name: Li, Fangxing
Publisher: name: arXiv
Year: 2021
Subjects: subject: Systems and Control (eess.SY)
subject: Machine Learning (cs.LG)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: With the increasing penetration of renewable energy, frequency response and its security are of significant concerns for reliable power system operations. Frequency-constrained unit commitment (FCUC) is proposed to address this challenge. Despite existing efforts in modeling frequency characteristics in unit commitment (UC), current strategies can only handle oversimplified low-order frequency response models and do not consider wide-range operating conditions. This paper presents a generic data-driven framework for FCUC under high renewable penetration. Deep neural networks (DNNs) are trained to predict the frequency response using real data or high-fidelity simulation data. Next, the DNN is reformulated as a set of mixed-integer linear constraints to be incorporated into the ordinary UC formulation. In the data generation phase, all possible power injections are considered, and a region-of-interests active sampling is proposed to include power injection samples with frequency nadirs closer to the UFLC threshold, which significantly enhances the accuracy of frequency constraints in FCUC. The proposed FCUC is verified on the the IEEE 39-bus system. Then, a full-order dynamic model simulation using PSS/E verifies the effectiveness of FCUC in frequency-secure generator commitments.
Tunneling anisotropic magnetoresistance and spin-orbit coupling in Fe/GaAs/Au tunnel junctions
Creators: name: Moser, J.
name: Matos-Abiague, A.
name: Schuh, D.
name: Wegscheider, W.
name: Fabian, J.
name: Weiss, D.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report the observation of tunneling anisotropic magnetoresistance effect (TAMR) in the epitaxial metal-semiconductor system Fe/GaAs/Au. The observed two-fold anisotropy of the resistance can be switched by reversing the bias voltage, suggesting that the effect originates from the interference of the spin-orbit coupling at the interfaces. Corresponding model calculations reproduce the experimental findings very well.
description: 5 pages, 3 figures, submitted to Phys. Rev. Lett
title: Extracting interpretable patterns from omics data with deep generative models under sample size constraints
Creators: name: Hess, Moritz
name: Lenz, Stefan
name: Binder, Harald
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: deep-learning
subject: variational autoencoder
subject: pattern extraction
subject: clustering
subject: single-cell
subject: 610 Medical sciences; Medicine

description: Background: Deep generative models such as Deep Boltzmann Machines (DBM) or variational autoencoders (VAE) are now frequently employed on omics data, such as single-cell gene expression data. These models learn non-linear dependencies in the data and allow for extracting compact latent representations[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Plan de marketing para la empresa Chocobrand
Creators: name: Ramirez Sanchez, Karen Valeria
name: Igua Porras, Freddy Aldemar
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Mercadeo - Estudios de caso
subject: Organización - Aspectos sociales
subject: Estructura organizacional - Aspectos socioeconómicos
subject: Plan de Marketing
subject: Empresa
subject: Confitería
subject: Diagnóstico
subject: Pyme

description: Plan de Marketing para empresa de chocolatería ubicada en Colombia llamada Chocobrand. Este documento contiene análisis, diagnóstico y plan de mejora en áreas de Mercadeo y Comercial según contexto actual de 2024 de la industria de la confitería. Así, este documento cuenta con estrategias centradas en el Mercadeo Digital, promoviendo en la compañía acogerse a la tendencia de mercado y economía global que le ayudará al cumplimiento de su objetivo de negocio.
description: Marketing Plan for a chocolate company located in Colombia called Chocobrand. This document contains analysis, diagnosis and improvement plan in Marketing and Commercial areas according to the current context of 2024 of the confectionery industry. Thus, this document has strategies focused on Digital Marketing, promoting the company to embrace the market trend and global economy that will help the fulfillment of its business goal.
Classification and monogamy of three-qubit biseparable Bell correlations
Creators: name: Seevinck, Michael
Publisher: name: arXiv
Year: 2007
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We strengthen the set of Bell-type inequalities presented by Sun & Fei [Phys. Rev. A 74, 032335 (2006)] that give a classification for biseparable correlations and entanglement in tripartite quantum systems. We will furthermore consider the restriction to local orthogonal spin observables and show that this strengthens all previously known such tripartite inequalities. The quadratic inequalities we find indicate a type of monogamy of maximal biseparable three-particle quantum correlations, although the nonmaximal ones can be shared. This is contrasted to recently found monogamy inequalities for bipartite Bell correlations in tripartite systems.
description: Accepted final version for PRA. 6 pages
title: Reproducible bioinformatics workflows: A case study with software containers and interactive notebooks
Creators: name: Eggert, Anja
name: Westermark, Pål Olof
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: reproducibility
subject: jupyter
subject: docker
subject: 610 Medical sciences; Medicine

description: Background: Reproducible specification of workflows in bioinformatics is challenging given their complexity. We developed a new statistical method in the field of circadian rhythmicity, which allows to rigorously determine whether measured quantities such as gene expression are not rhythmic. The statistical[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Compact Modeling of Ultra-Scaled Triple-Gate FinFETs in Verilog-A:
Creators: name: Μεσσάρης, Ιωάννης Γεωργίου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Τρανζίστορ πολλαπλής πύλης
Συμπαγής μοντελισμός
Ταλαντωτής δαχτυλιδιού
FinFET
Verilog-A
Ring oscillator

description: Θέμα της παρούσας εργασίας, ήταν η γραφή ενός συμπαγούς μοντέλου για τα FinFETs τριπλής πύλης. Για το σκοπό αυτό επιλέχθηκε η γλώσσα περιγραφής αναλογικών συστημάτων Verilog-A v2.2. Στο πρώτο κεφάλαιο παρουσιάζονται αρκετά από τα πλεονεκτήματα της τεχνολογίας που χρησιμοποιείται στα FinFETs σε σχέση με την ευρέως χρησιμοποιούμενη τεχνολογία των MOSFETs. Στο δεύτερο κεφάλαιο παρατίθεται μια σύντομη περιγραφή της γλώσσας Verilog-A και αξιολογείται η απόδοση της, όταν χρησιμοποιείται για την υλοποίηση συμπαγών μοντέλων τρανζίστορ. Τα κεφάλαια 3 και 4 ενσωματώνουν τα πειράματα που πραγματοποιήθηκαν στην παρούσα εργασία. Στο κεφάλαιο 3 παρατίθενται τρεις εναλλακτικές υλοποιήσεις του FinFET τριπλής πύλης στη γλώσσα Verilog-A. Στο τελευταίο κεφάλαιο προσομοιώνονται ταλαντωτές τριών και δεκαπέντε σταδίων με βάση τα μοντέλα που αναπτύχθηκαν.
description: The subject of this thesis is focused on the compact modeling of Triple Gate FinFETs, with the use of the Verilog-A analog modeling language. In the first chapter we present the advantages of FinFET technology compared to MOSFET technology. Chapter 2 is oriented towards the description of the Verilog-A language and its performance when used for compact modeling. The basic processes that take place in a circuit simulator are presented and the Newton-Raphson algorithm is analyzed. Chapters 3 and 4 embody the experimental work conducted in this thesis. In chapter 3, three alternative Verilog-A models for the TG-FinFET are presented. The input and transfer characteristics and the capacitance-voltage characteristics of the analytical models are then compared with TCAD simulation results. In the final chapter 3-stage and 15-stage ring oscillators were simulated with the Verilog-A analytical implementations of the TG-FinFETs. The simulations were conducted with the Spectre circuit simulation tool which comes along Cadence Virtuoso.
title: The Knowledge Connector: Workflow Support for Molecular Tumor Boards
Creators: name: Glocker, Katrin
name: Knurr, Alexander
name: Nürnberger, Sylvia
name: Al-Hmad, Janine
name: Czogalla, Dennis-Immanuel
name: Izzo, Marvin
name: Koch, Christian
name: Kreutzfeldt, Simon
name: Roth, Benjamin
name: Ückert, Frank
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: precision medicine
subject: molecular tumor board
subject: workflow support
subject: 610 Medical sciences; Medicine

description: In times where the genetic screening of patient material is not only technically, but also financially feasible the demand to treat people specifically based on their genetic characteristics is increasing. This demand is met using precision medicine in molecular tumor boards (MTB). To prepare these [for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Determination Of The Orbit Of The Planetary Companion To The Metal Rich Star HD 45350
Creators: name: Endl, Michael
name: Cochran, William D.
name: Wittenmyer, Robert A.
name: Hatzes, Artie P.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the precise radial velocity (RV) data for the metal-rich star HD 45350 collected with the Harlan J. Smith (HJS) 2.7 m telescope and the Hobby-Eberly Telescope (HET) at McDonald Observatory. This star was noticed by us as a candidate for having a giant planetary companion in a highly eccentric orbit, but the lack of data close to periastron left the amplitude and thus mass of the planet poorly constrained. Marcy et al. (2005) announced the presence of the planet based on their Keck/HIRES data, but those authors also cautioned that the remaining uncertainties in the orbital solution might be large due to insufficient data near periastron passage. In order to close this phase gap we exploited the flexible queue scheduled observing mode of the HET to obtain intensive coverage of the most recent periastron passage of the planet. In combination with the long term data from the HJS 2.7 m telescope we determine a Keplerian orbital solution for this system with a period of 962 days, an eccentricity of e=0.76 and a velocity semi-amplitude K of 57.4 m/s. The planet has a minimum mass of m sin i = 1.82 +- 0.14 M_Jup and an orbital semi-major axis of a = 1.92 +-0.07 AU.
description: 9 pages preprint, 4 figures, accepted in AJ
Οι σχέσεις των Ρουμανικών Χωρών με το Βυζάντιο μέχρι το 18ο αιώνα:
Creators: name: Musat, Mihai Constantin Stefan (Μουσάτ Μιχαήλ Κωνσταντίνος)
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Βυζαντιο
Σχεσεις
Ρουμανια
Bizantium
Relations
Romania

description: Η παρούσα μεταπτυχιακή εργασία πραγματοποιήθηκε στο Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Θεολογική Σχολή, Τμήμα Ποιμαντικής και Κοινωνικής Θεολογίας. Στόχος αυτής της μεταπτυχιακής εργασίας είναι η μελέτη των επιδράσεων της Βυζαντινής Αυτοκρατορίας βόρεια του Δουνάβεως, δηλαδή στις Ρουμανικές Χώρες. Η εργασία αρχίζει με σύντομη παρουσίαση του Βυζαντινισμού και συνεχίζει με ανασκόπηση των σχέσεων και των επιρροών του Βυζαντίου στα Ρουμανικά ιδρύματα, στη λογοτεχνία και τέχνη, τα όσα σχετικά για τους Φαναριτότες και στις επιδράσεις στην Ρουμανική Εκκλησία. Θέλω να ευχαριστήσω τον καθοδηγούντα τη σύνταξη της εν λόγο εργασίας, τον Εντιμότατον Κύριον Μιχαήλ Τρίτος, καθηγητή της Θεολογικής Σχολής του Αριστοτελείου Πανεπιστημίου Θεσσαλονίκης, Τμήμα Ποιμαντικής και Κοινωνικής Θεολογίας, ο οποίος με βοήθησε πάρα πολύ ώστε να ολοκληρωθεί αυτό το πόνημα. Τον ευχαριστώ πολύ για όλα όσα μου δίδαξε, για το επιστημονικό υλικό που μου προσέφερε, τις συμβουλές του, την συμπαράστασή του και τις ώρες που μου αφιέρωσε. Επίσης, θα ήθελα να ευχαριστήσω και τον Κύριον Kαραθανάσην Αθανάσιον καθηγητή της Θεολογικής Σχολής του ιδίου Πανεπιστημίου, Τμήμα Ποιμαντικής και Κοινωνικής Θεολογίας, όπως και τον Κύριο Κουκουσά Βασίλειον, Επίκουρον Καθηγητήν, για την βοήθειά τους. Τέλος, ευχαριστώ την οικογένεια μου για την υπομονή της όλο το διάστημα της συγγραφής της εργασίας ταύτης, καθώς και για τη στήριξη της στην προσπάθεια μου να φέρω αυτό το έργο εις πέρας.
description: The present master thesis entitled “Relations of the Romanian Countries with Byzantium till the 18th century” was drafted at Aristotle University - Thessaloniki, Faculty of Theology, pastoral and social theology branch. The purpose of this master thesis is to study the influences of the Byzantium Empire in the North of the River Danube, namely in the Romanian Countries. The work begins with a short presentation of Byzantium and continues with a detailed presentation of the relations and influences of Byzantium in the Romanian institutions, in logo-techniques, in art, as well as in everything related to the Phanarian epoch. I do thank my supervisor teacher for structuring the present work, Mr. Mihail Tritos, Professor of the Faculty of Theology within the Aristotle University, pastoral and social theology branch, who helped me a lot to finish this difficult task. I do thank him for everything he taught me, for the bibliography he gave me, for his good advice, for having encouraged me, as well as for the time granted. I also thank Mr. Prof. Athanasios Karathanasios, Professor at the same Faculty, as well as Mr. Vasilios Koukousas for the help given. Finally, I thank my family for the patience shown during this period of drafting and delivering this theological thesis up to the end.
The ChemicalToolBox – computational chemistry in Galaxy
Creators: name: Bray, Simon
name: Alireza Khanteymoori
name: Grüning, Björn
Publisher: name: F1000 Research Limited
Year: 2019

description: New methods in drug discovery, such as combinatorial chemistry and high-throughput screening, have resulted in the creation of huge amounts of new chemical data. The need to analyse this data effectively has spawned the field of cheminformatics, which applies computational methods to chemical problems. Numerous toolkits and applications have been developed for this purpose, both open-source and commercial; however, they often demand knowledge of a programming language or familiarity with the command line from the user. Incorporating a selection of tools into Galaxy would obviate this requirement, thus improving accessibility to the field for users that lack these technical skills.

To this end, we introduce the ChemicalToolBox, a collection of tools for downloading, processing, analysing and visualising chemical structures. Tools draw on a number of open-source toolkits (e.g. RDKit, OpenBabel) and offer functionalities including compound clustering, structure searches, fragment calculations, and drug-likeness calculation. Together with these tools, we provide several example workflows which combine tools into a full cheminformatic pipeline. We also provide training material for users new to cheminformatics or unfamiliar with Galaxy.

Currently, we offer the ChemicalToolBox as a self-contained suite, downloadable in the form of a Docker container. Alternatively, all tools can be accessed via https://usegalaxy.eu/. We have developed a Galaxy ‘flavour’ devoted to computational chemistry, which can be accessed via https://cheminformatics.usegalaxy.eu/.
Έλεγχος, αξιολόγηση και ανάλυση χρονοσειρών ημερησίων δεδομένων από την ηλεκτρονική βάση του ncdc για τον προσδιορισμό αλλαγών σε κύριες κλιματικές παραμέτρους:
Creators: name: Δεμερτζής, Κωνσταντίνος Γεωργίου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Χρονοσειρές
Μετεωρολογικά δεδομένα
Ηλεκτρονική βάση ncdc
Timeseries
Meteorological data
ncdc database

description: Σε αυτή την εργασία γίνεται έλεγχος, αξιολόγηση και ανάλυση χρονοσειρών ημερησίων κλιματολογικών δεδομένων που αποκτήθηκαν από την ηλεκτρονική βάση του Εθνικού Κέντρου Μετεωρολογικών δεδομένων (NCDC). Τα δεδομένα αφορούν μετεωρολογικούς σταθμούς αποκλειστικά του Ελλαδικού χώρου και στόχος ήταν ο προσδιορισμός ενδεχόμενων αλλαγών σε κύριες κλιματικές παραμέτρους. Αρχικά γίνεται παρουσίαση του ρόλου και των στόχων του Παγκόσμιου Μετεωρολογικού Οργανισμού (WMO) και του NCDC από το οποίο προήλθαν τα δεδομένα. Δίνεται ο ορισμός των χρονοσειρών μετεωρολογικών δεδομένων και αναφέρονται τρόποι με τους οποίους μπορούν να συμπληρωθούν ελλείπουσες τιμές αυτών. Επιπλέον δίνονται τα βασικά στάδια που περιλαμβάνει μια ανάλυση χρονοσειρών μετεωρολογικών δεδομένων. Στο δεύτερο κεφάλαιο αναλύεται ο τρόπος με τον οποίο αποκτήθηκαν και ταξινομήθηκαν τα δεδομένα. Γίνεται έλεγχος και αξιολόγηση των διαθέσιμων δεδομένων, προσδιορίζεται εάν υπάρχει επαρκής ημερήσια διαθεσιμότητα και τυχόν ελλείψεις στις βασικές κλιματικές παραμέτρους. Από το σύνολο των διαθέσιμων σταθμών επιλέγονται αυτοί που πληρούν τα κριτήρια για τον σχεδιασμό αξιόπιστων χρονοσειρών. Τέλος στο τρίτο κεφάλαιο σχεδιάζονται οι χρονοσειρές θερμοκρασίας και κατακρημνίσεων των σταθμών που επιλέχθηκαν και προσδιορίζεται ενδεχόμενη μεταβολή τους κατά τη διάρκεια του χρόνου, μέσω της τάσης των χρονοσειρών.
description: This study is about checking, evaluation and analysis of time series of daily weather data obtained from the electronic database of National Climatic Data Center (NCDC). The data relate to meteorological stations exclusively of Greece and the aim was to identify any changes in key climate parameters. Initially, there is a presentation of the role and objectives of the World Meteorological Organization (WMO) and NCDC from which the data originated. There is given the definition of the time series of meteorological data and figured out ways that can be filled in missing values. In addition, there are given the key stages that includes an analysis of time series of meteorological data. The second chapter discusses the way in which data were acquired and registered. There is checking and evaluation of the available data and determined if there is adequate availability and any deficiencies in key climate parameters. From the set of available stations there are chosen those that meet the criteria for the design of reliable time series. Finally in the third chapter, there are temperature and precipitation time series of channels selected and there is identified any possible variation over time, through the trend of time series.
Simulation of Jet Quenching Observables in Heavy Ion Collisions at the LHC
Creators: name: Roland, Christof
name: Veres, Gábor I.
name: Krajczár, Krisztián
Publisher: name: arXiv
Year: 2007
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Large transverse momentum jets provide unique tools to study dense QCD matter in high-energy heavy-ion collisions. Results from RHIC on suppression of high transverse momentum particles in Au+Au collisions indicate a significant energy loss of leading partons in the dense and strongly interacting matter formed in these collisions. The LHC will collide Pb ions at sqrt(s_NN)=5500 GeV, where the cross section of hard scattering will increase dramatically. Large production rates, the large acceptance of the CMS calorimeters and tracking system, combined with the capability of triggering on jets, will extend the transverse momentum reach of charged particle spectra and nuclear modification factors up to p_T>200 GeV/c.
description: 6 pages, 5 figures. Presented at the 19th International Conference on Ultra-Relativistic Nucleus-Nucleus Collisions (QM2006), Shanghai, China, November 14-20, 2006. [Grant numbers added in the acknowledgment.]
Disputa sobre “embriones” y abuso en el ejercicio del derecho de revocatoria a su implantación: consideraciones para el derecho colombiano
Creators: name: Salgado Ramírez, Catalina
Publisher: name: Universidad Externado de Colombia
Year: 2020
Subjects: subject: Reproducción humana -- Aspectos jurídicos
subject: Responsabilidad médica -- Aspectos jurídicos
subject: Genética humana
subject: Abuso del derecho
subject: Derecho y ética
subject: ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades
subject: ODS 5: Igualdad de género. Lograr la igualdad de género y empoderar a todas las mujeres y las niñas
subject: ODS 10: Reducción de las desigualdades. Reducir la desigualdad en los países y entre ellos
subject: Embriones
subject: Abuso del derecho
subject: Revocatoria del consentimiento
subject: Consentimiento informado
subject: Implantación de embriones
subject: Proyecto parental

description: El objetivo del presente trabajo es abordar la pregunta sobre si el ejercicio del derecho a la revocatoria del consentimiento a la implantación de embriones por parte de uno de los aportantes de material genético puede analizarse desde la teoría del abuso del derecho y si, como consecuencia, es posible limitar su ejercicio. Para tal propósito, este trabajo analiza, en primer lugar, las decisiones más relevantes de los tribunales extranjeros a propósito de las disputas sobre embriones, y propone, en segundo lugar, una serie de criterios para el juez a fin de valorar los intereses de las partes en disputa y las posibles consecuencias jurídicas de la eventual implantación.
title: Kommunikation und Entscheidungsfindung auf der Basis unsicherer Daten bei persönlicher Betroffenheit
Creators: name: Keinki, Christian
name: Poeck, Juliane
name: Salomo, Sarah
name: Hübner, Jutta
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: Evidenz
subject: fortgeschrittene Krebserkrankung
subject: Therapiealternativen
subject: Abwägen von Chancen und Risiken
subject: Lebensqualität
subject: Überleben
subject: 610 Medical sciences; Medicine

description: Hintergrund: Die moderne Therapie von Krebserkrankungen ist eine hoch komplexe Abfolge unterschiedlicher Methoden wie Operation, verschiedene Formen der Strahlentherapie, unterschiedlichste Medikamente allein oder in Kombination gegeben. Zu allen diesen Therapieverfahren als Einzelschritte wie auch [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
title: Can genetic similarity explain microbiome similarity in Inflammatory Bowel Diseases?
Creators: name: Sharma, Arunabh
name: Freitag-Wolf, Sandra
name: Krawczak, Michael
name: Dempfle, Astrid
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Over 200 inflammatory bowel diseases risk loci have been identified[ref:1]. Several studies aim to find a connection between the host microbiome and inflammatory bowel diseases. In family-based designs, one can leverage the amount of shared genetic material to a phenotype of interest.[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Additional file 3 of The stability of the coiled-coil structure near to N-terminus influence the heat resistance of harpin proteins from Xanthomonas
Creators: name: Liu, Yue
name: Zhou, Xiaoyun
name: Liu, Wenbo
name: Miao, Weiguo
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 3. Secondary structural changes of four Hpa1 proteins under four different temperatures. (A) CD spectra of four Hpa1 proteins measured after 10 min incubation at 28 °C. (B). Secondary structural contents (%) of four Hpa1 proteins after temperature treatment at 28 °C, 100 °C, 150 °C, or 200 °C. Secondary structural contents were calculated using Jasco’s Spectra. Manager TM software. Detailed results are presented in the table on the right-hand side. The α-helical content of the four Hpa1 and GST proteins after treatment at 200 °C treatment is shown in red.
Hadronization of Dense Partonic Matter
Creators: name: Fries, Rainer J.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The parton recombination model has turned out to be a valuable tool to describe hadronization in high energy heavy ion collisions. I review the model and revisit recent progress in our understanding of hadron correlations. I also discuss higher Fock states in the hadrons, possible violations of the elliptic flow scaling and recombination effects in more dilute systems.
description: 8 pages, 4 figures; plenary talk delivered at SQM 2006, to appear in J. Phys. G
title: Testing methods to analyze small sample size GWAS with different settings
Creators: name: Poplawski, Alicia
name: Strauch, Konstantin
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: GWAS
subject: SNP
subject: analysis
subject: small sample size
subject: 610 Medical sciences; Medicine

description: Background: Due to small effect sizes and the huge number of tested single-nucleotide polymorphisms (SNPs) genome-wide association studies (GWAS) require very large sample sizes, in order to identify genetic variants associated with a genetic disease. However, often only fairly small sample sizes are[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Towards measuring Entanglement Entropies in Many Body Systems
Creators: name: Klich, Israel
name: Refael, Gil
name: Silva, Alessandro
Publisher: name: arXiv
Year: 2006
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We explore the relation between entanglement entropy of quantum many body systems and the distribution of corresponding, properly selected, observables. Such a relation is necessary to actually measure the entanglement entropy. We show that in general, the Shannon entropy of the probability distribution of certain symmetry observables gives a lower bound to the entropy. In some cases this bound is saturated and directly gives the entropy. We also show other cases in which the probability distribution contains enough information to extract the entropy: we show how this is done in several examples including BEC wave functions, the Dicke model, XY spin chain and chains with strong randomness.
title: Reducing systems biology models to derive mechanism-based drug effect models: blood coagulation as illustrative example
Creators: name: Falkenhagen, Undine
name: Knöchel, Jane
name: Kloft, Charlotte
name: Huisinga, Wilhelm
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: model order reduction
subject: drug effect
subject: blood coagulation
subject: 610 Medical sciences; Medicine

description: Background: Comprehensive knowledge about pharmacologically relevant processes is comprised in large-scale systems biology models. While these models thus contain important biological information, their complexity renders them unsuitable for parameter estimation, e.g. when analysing clinical data. It[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
A Novel Method to Construct Stationary Solutions of the Vlasov Maxwell system
Creators: name: Suzuki, Akihiro
name: Shigeyama, Toshikazu
Publisher: name: arXiv
Year: 2008
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A novel method to derive stationary solutions of the Vlasov-Maxwell system is established. This method is based on the assumption that the deviation of the velocity distribution from the Maxwell-Boltzmann distribution can be expanded by the Hermite polynomials. By applying our method, a new two-dimensional equilibrium is derived, which may provide an initial setup for investigations of three-dimensional collisionless reconnection of magnetic fields.
description: 14 pages, 2 figures. to appear in Phys. Plasmas
Effective creases and contact angles between membrane domains with high spontaneous curvature
Creators: name: Fournier, Jean-Baptiste
name: Amar, Martine Ben
Publisher: name: arXiv
Year: 2006
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We show that the short-scale elastic distortions that are excited in the vicinity of the joint between different lipidic membrane domains (at a scale of \~10 nm) may produce a "crease" from the point of view of the standard elastic description of membranes, i.e., an effective discontinuity in the membrane slope at the level of Helfrich's theory. This "discontinuity" may be accounted for by introducing a line tension with an effective angular dependence. We show that domains bearing strong spontaneous curvatures, such as biological rafts, should exhibit creases with a finite contact-angle, almost prescribed, corresponding to a steep extremum of the line energy. Finite contact-angles might also occur in symmetric membranes from the recruitment of impurities at the boundary.
Evaluation de l'activité antipyrétique, analgésique et anti-inflammatoire de l'extrait méthanolique de Vitex congolensis De Wild. & T. Durand
Creators: name: Victor, Okombe Embeya
name: Gael, Nzuzi Mavungu
Publisher: name: Zenodo
Year: 2019
Subjects: Activité
anti-inflammatoire
Vitex congolensis De Wild

description: Abstract Contexte
 Vitex congolensis De Wild (Lamiaceae) est une plante médicinale utilisée dans le traitement des pathologies à composante inflammatoire.
 Objectif
 L’étude avait pour objectif d’évaluer les activités antipyrétique, analgésique et anti-inflammatoire de l’extrait méthanolique de la poudre de cette espèce.
 Méthodes
 Quatre lots d’animaux ont été constitués dont deux recevant respectivement 100 mg et 300 mg de l’extrait méthanolique par kg de poids corporel par voie orale en comparaison avec un lot témoin positif recevant soit le paracétamol (p.o) soit le diclofénac en intrapéritonéale et un lot témoin négatif ayant reçu soit de l’eau distillée (p.o) soit du sérum physiologique en intrapéritonéale (i.p).
 Résultats
 Le traitement avec 300 mg d’extrait par kilos a montré un effet significatif (P<0,05) à la première heure (36,50±1,41) puis à la troisième (36,85±0,91) après induction de la fièvre. Cette dernière a été réduite 97,14% avec le paracétamol au T3 ; 95,12 % avec 300 mg de l’extrait (T1) et 82,35 % avec 100 mg de l’extrait (T2). Les différents traitements (Diclofénac 10 mg, V. congolensis 100 mg et 300 mg) préviennent de façon significative (P<0,05) les manifestations douloureuses (15,75±8,18 ; 25,00 ±1,15 et 10,25±1,26) respectivement contre 145,00 ± 10,00 pour le lot témoin avec un excellent pourcentage d’inhibition de contorsions (92,93 %) observé après l’administration de 300 mg de l’extrait. Les deux doses préviennent le processus inflammatoire comparativement aux lots standard et contrôle négatif.

 Conclusion
 L’étude a montré que l’extrait méthanolique d’écorces de racine de Vitex congolensis pourrait avoir des effets anti-inflammatoires intéressants.