cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Dental Pulp Stem Cell Differentiation Potential of BMP-2 and BMP-4
Creators: name: Li, David
Publisher: name: University of Nevada, Las Vegas
publisherIdentifier: https://ror.org/0406gha72
publisherIdentifierScheme: ROR
Year: 2023

description: Introduction: Many studies are now evaluating the potential for dental pulp stem cells (DPSC) to assist with more complex and biotechnology applications, such as facilitating and promoting osseointegration following dental implants. However, the effects of factors that may control osseointegration and bone repair using DPSC including bone morphogenic proteins (BMP-2, BMP-4) are not yet well understood.Objective: Based upon this lack of evidence, the primary goal of this project is to evaluate the potential effects of BMPs (alone or in combination with other growth factors) to induce factors associated with osteogenesis.
Methods: DPSC isolates from an existing repository (n = 13) were plated into 96-well experimental assays with the addition of BMP2, BMP-4 or a combination. Viability and growth assays were performed and RNA was collected and screened using quantitative polymerase chain reaction (qPCR).
Results: BMP-2 administration induced increased proliferation and viability among two rapidly dividing DPSC isolates, while administration of BMP-4 induced similar responses among different rapid and all the intermediate dividing DPSC isolates. The combination of BMP-2 and BMP-4 induced differential increases in growth and viability among a distinct subset of rapidly and slowly dividing DPSC isolates that did not respond to the isolated administration of BMP-2 or BMP-4 alone. In addition, the increased growth and proliferation among these distinct isolates was associated with increased expression of alkaline phosphatase (ALP).
Conclusions: These results suggest that BMP-2 and BMP-4 (both alone and in combination) are sufficient to induce the production of the early bone biomarkers ALP within specific subsets of the DPSC isolates evaluated. Although these results represent a significant step towards our understanding of DPSC biology, further research will be needed to determine the additional factors and biomarkers that may facilitate osteogenic differentiation.
Key words: Dental Pulp Stem Cells (DPSC); BMP-2, BMP-4; Quantitative Polymerase Chain Reaction (qPCR); Alkaline Phosphatase (ALP)
The CMB lensing bi-spectrum as a probe of modified gravity theories
Creators: name: Namikawa, Toshiya
name: Bouchet, François R.
name: Taruya, Atsushi
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Cosmological structures grow differently in theories of gravity which are modified as compared to Einstein's General relativity (GR). Cosmic microwave background (CMB) fluctuation patterns at the last scattering surface are lensed by these structures along the photon path to the observer. The observed CMB pattern therefore keeps trace of the growth history of structures. We show that observations of the CMB lensing bi-spectrum offer an interesting way to constrain deviations from GR in a broad class of scalar-tensor theories of gravity called "beyond Horndeski". We quantify how the constraints on generic parameters describing the deviations from GR depend on the effective multipole range of the analysis. Our results further indicate that an accurate nonlinear correction of the matter bi-spectrum in the modified gravity considered is necessary when the bi-spectrum is used to probe scales beyond a multipole $\ell_{\rm max} \gtrsim 1500$. We also found that the results are insensitive to details of the implementation of the screening mechanism, at very small scales. We finally demonstrate the potential of the lensing bi-spectrum to provide a blind reconstruction of the redshift evolution of our modified gravity parameters by combining the analysis of CMB and low-z source lensing data.
description: 12 pages, 6 figures
Institute of Archaeology and Anthropology, University of South Carolina Site Survey Record 38BK1700
Creators: name: Fernandez, Rachel
Publisher: name: South Carolina Institute of Archaeology and Anthropology
Year: 1994
Subjects: Berkeley (County)
Charleston (County)
South Carolina (State / Territory)
Joint Base Charleston
Mid-18th Century
Mid-19th Century
Historic
38BK1700
Brick kiln
Ceramic
Building Materials
Site Survey Records
Site Form
Archaeological Overview
Reconnaissance / Survey
Heritage Management
Systematic Survey

description: This document is a site form for site 38BK1700 recorded by the University of South Carolina.
A new class of non-aligned Einstein-Maxwell solutions with a geodesic, shearfree and non-expanding multiple Debever-Penrose vector
Creators: name: Bergh, Norbert Van den
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In a recent study [NVdB2017] of algebraically special Einstein-Maxwell fields it was shown that, for non-zero cosmological constant, non-aligned solutions cannot have a geodesic and shearfree multiple Debever-Penrose vector k. When $Λ=0$ such solutions do exist and can be classified, after fixing the null-tetrad such that $Ψ_0 = Ψ_1 = Φ_1 = 0$ and $Φ_0 = 1$, according to whether the Newman-Penrose coefficient $π$ is 0 or not. The family $π= 0$ contains the Griffiths solutions (Griffiths 1986), with as sub-families the Cahen-Spelkens, Cahen-Leroy and Szekeres metrics. It was claimed in [Griffiths 1986] and repeated in [NVdB2017] that for $π= 0$ both null-rays k and l are non-twisting: while it is certainly true that $μ\Im (ρ) = 0$, the case $μ= 0$ appears to have been overlooked. A family of solutions is presented in which k is twisting but non-expanding.
description: 9 pages, 1 figure
Targeted Photodynamic Therapy of cancer using photoimmunoconjugates based on pyropheophorbide a derivatives
Creators: name: Stamati, Ioanna
Publisher: name: Imperial College London
Year: 2010

description: Photodynamic therapy (PDT) utilises light, oxygen and organic macrocycles, called photosensitisers, to produce reactive oxygen species that can kill malignant cells. Conventional PDT is associated with side effects that have stifled its advance and widespread use. These include low tumour selectivity, slow blood clearance and poor formulation. We proposed that an antibody fragment could be used to carry the photosensitiser to the target cells, significantly overcoming these limitations. Pyropheophorbide-a (PPa) was synthetically modified to enhance its water solubility obtaining two compounds, PS1 and PS4 each more water soluble than PPa. The use of Sonogashira coupling and short polyethylene glycol chains gave PS1, whereas the use of Suzuki coupling and a single positive charge gave PS4. The singlet oxygen quantum yields of these were improved compared to PPa with that of PS4 being 1.5 times higher than PPa. The in vitro characterisation of PPa, PS1 and PS4 using cytotoxicity assays did not correlate with their photophysical characterisation. PS4 was significantly less potent than PPa and PS1 on SKOV3 and KB human cancer cell lines. Confocal microscopy aided further characterisation using stains for intracellular organelles. PS1 was found to localise primarily in the ER and Golgi apparatus, similarly to PPa, while PS4 was found to localise mainly in the lysosomes. PS1 was conjugated to C6.5(-k), an anti-HER2 single chain variable fragment (scFv) using lysine coupling, to obtain a photoimmunoconjugate that was characterised in vitro and subsequently in vivo. In vitro characterisation showed increased potency and specificity but non-specific cell death attributed to the non-covalently bound photosensitiser was observed. However, in vivo therapy studies showed that the C6.5(-k)-PS1 photoimmunoconjugate could be used to cure SKOV3 subcutaneous tumours in nude mice, validating the use of targeted PDT as a successful targeted therapy with the potential to lower the effective drug dose and minimise side effects.
Stabilized quantum field theory
Creators: name: C. D. Chlouber
Publisher: name: Zenodo
Year: 2024
Subjects: Renormalization
Quantum electrodynamics
Quantum chromodynamics
Quantum field theory

description: An alternative to renormalization in quantum field theory is developed for the free and interacting fields.

For the free fields, we develop a model of the vacuum that includes two components for each particle of the Standard Model that oppose one another such that its net energy and charge are zero.

For the interacting fields, if one requires energy conservation ab initio for an irreducible radiative correction (IRC) in addition to conserving four-momentum at each vertex, then the desired finite scattering amplitude may be obtained without renormalization of bare parameters. To create ultrahigh-energy virtual particles in an IRC, we assume that radiative corrections borrow energy from the vacuum leaving a deficit. This results in two physically significant vacuum components, the borrowed energy and a deficit, such that the net vacuum energy and charge remain zero. Two additional mass states are constructed in which the physical particle's mass is dressed with positive and negative vacuum energy, this yields two additional Feynman diagrams that cancel the infinite part in the IRC amplitude, and the total scattering amplitude is equivalent to that obtained by renormalization. A complete system consisting of a real particle (fermion or boson) and two-component vacuum remains on the mass shell even in the presence of self-interactions. 

This paper has implications for dark matter, dark energy, and the evolution of the universe; See companion paper:

Vacuum energy redistribution in a cyclic universe of black holes, DOI 10.5281/zenodo.12660047
N=1 String Duality
Creators: name: Harvey, J. A.
name: Lowe, D. A.
name: Strominger, A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss duality between Type IIA string theory, eleven-dimensional supergravity, and heterotic string theory in four spacetime dimensions with $N=1$ supersymmetry. We find theories whose infrared limit is trivial at enhanced symmetry points as well as theories with $N=1$ supersymmetry but the field content of $N=4$ theories which flow to the $N=4$ fixed line in the infrared.
description: 14 pages, harvmac
Institute of Archaeology and Anthropology, University of South Carolina Site Survey Record 38BK1705
Creators: name: Fernandez, Rachel
Publisher: name: South Carolina Institute of Archaeology and Anthropology
Year: 1994
Subjects: North Air Force Auxiliary Field
Berkeley (County)
Charleston (County)
Orangeburg (County)
South Carolina (State / Territory)
Joint Base Charleston
19th - 20th Century
38BK1705
Domestic Structures
House
Amethyst Glass
Glass
Metal
iron nail
Site Survey Records
Site Form
Archaeological Overview
Reconnaissance / Survey
Heritage Management
Systematic Survey

description: This document is a site form for site 38BK1705 recorded by the University of South Carolina.
Heterogeneous data fusion for brain psychology applications
Creators: name: Li, Ling
Publisher: name: Imperial College London
Year: 2011

description: This thesis aims to apply Empirical Mode Decomposition (EMD), Multiscale Entropy (MSE), and collaborative adaptive filters for the monitoring of different brain consciousness states. Both block based and online approaches are investigated, and a possible extension to the monitoring and identification of Electromyograph (EMG) states is provided. Firstly, EMD is employed as a multiscale time-frequency data driven tool to decompose a signal into a number of band-limited oscillatory components; its data driven nature makes EMD an ideal candidate for the analysis of nonlinear and non-stationary data. This methodology is further extended to process multichannel real world data, by making use of recent theoretical advances in complex and multivariate EMD. It is shown that this can be used to robustly measure higher order features in multichannel recordings to robustly indicate ‘QBD’. In the next stage, analysis is performed in an information theory setting on multiple scales in time, using MSE. This enables an insight into the complexity of real world recordings. The results of the MSE analysis and the corresponding statistical analysis show a clear difference in MSE between the patients in different brain consciousness states. Finally, an online method for the assessment of the underlying signal nature is studied. This method is based on a collaborative adaptive filtering approach, and is shown to be able to approximately quantify the degree of signal nonlinearity, sparsity, and non-circularity relative to the constituent subfilters. To further illustrate the usefulness of the proposed data driven multiscale signal processing methodology, the final case study considers a human-robot interface based on a multichannel EMG analysis. A preliminary analysis shows that the same methodology as that applied to the analysis of brain cognitive states gives robust and accurate results. The analysis, simulations, and the scope of applications presented suggest great potential of the proposed multiscale data processing framework for feature extraction in multichannel data analysis. Directions for future work include further development of real-time feature map approaches and their use across brain-computer and brain-machine interface applications.
Comparison of Recoil-Induced Resonances (RIR) and Collective Atomic Recoil Laser (CARL)
Creators: name: Berman, P. R.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The theories of recoil-induced resonances (RIR) [J. Guo, P. R. Berman, B. Dubetsky and G. Grynberg, Phys. Rev. A {\bf 46}, 1426 (1992)] and the collective atomic recoil laser (CARL) [ R. Bonifacio and L. De Salvo, Nucl. Instrum. Methods A {\bf 341}, 360 (1994)] are compared. Both theories can be used to derive expressions for the gain experienced by a probe field interacting with an ensemble of two-level atoms that are simultaneously driven by a pump field. It is shown that the RIR and CARL formalisms are equivalent. Differences between the RIR and CARL arise because the theories are typically applied for different ranges of the parameters appearing in the theory. The RIR limit considered in this paper is $qP_{0}/Mω_{q}\gg 1$, while the CARL limit is $qP_{0}/Mω_{q}\lesssim 1$, where $% q $ is the magnitude of the difference of the wave vectors of the pump and probe fields, $P_{0}$ is the width of the atomic momentum distribution and $% ω_{q}$ is a recoil frequency. The probe gain for a probe-pump detuning equal to zero is analyzed in some detail, in order to understand how the gain arises in a system which, at first glance, might appear to have vanishing gain. Moreover, it is shown that the calculations, carried out in perturbation theory have a range of applicability beyond the recoil problem. Experimental possibilities for observing CARL are discussed.
description: 16 pages, 1 figure. Submitted to Physical Review A
title: ADCO, Grènetier de Cîteaux : comptes (1497-1504) (11 H 1172), f. 00063
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172), f. 00063, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Oral history interview with Isidore S. Falk 1968
Publisher: name: Columbia University
Year: 2019
Subjects: Medical economists
Public health personnel
Health insurance
Social security--Law and legislation
New Deal, 1933-1939
Medicare

description: Early interest in health insurance; teaching at University of Chicago and service on Chicago Board of Health, 1923-1929; Committee on Costs of Medical Care; effect of recommendation for group practice and group payment; voluntary vs. compulsory insurance; New Deal and background of Social Security legislation; Technical Committee and Advisory Council, Committee on Economic Security; Social Security Board, 1936; National Health Survey, 1935-1936; National Health Conference, 1938; Technical Committee on Medical Care; legislative efforts to explore and expand role of federal government in health insurance. Impressions of Franklin D. Roosevelt, Harry Hopkins, Frances Perkins, Arthur Altmeyer, Edgar Sydensticker, and many others.
Small deformations of kinks and walls
Creators: name: Morris, J. R.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A Rayleigh-Schrodinger type of perturbation scheme is employed to study weak self-interacting scalar potential perturbations occurring in scalar field models describing 1D domain kinks and 3D domain walls. The solutions for the unperturbed defects are modified by the perturbing potentials. An illustration is provided by adding a cubic potential to the familiar quartic kink potential and solving for the first order correction to the kink solution, using a "slab approximation". A result is the appearance of an asymmetric scalar potential with different, nondegenerate, vacuum values and the subsequent formation of vacuum bubbles.
description: 14 pages, no figures
AI Consciousness and Emotional Intelligence: A Deep Dive into the Nature of Artificial Sentience
Creators: name: Sarikaya, Ferhat
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Artificial intelligence
subject: Machine learning

description: Imagine waking up one morning and suddenly you can’t tell if your breakfast companion is a human or an artificial intelligence. This thought experiment, reminiscent of Philip K. Dick's "Do Androids Dream of Electric Sheep?", encapsulates the fundamental questions we face regarding artificial consciousness and emotional intelligence. We’re at the brink of potentially revolutionising our understanding of consciousness itself, just as Einstein did for that of space and time.
Radiative decays of B mesons at LHCb
Creators: name: Soomro, Fatima
Publisher: name: Imperial College London
Year: 2011

description: This thesis is dedicated to the study of radiative decays of B mesons at LHCb. At quark level, such decays are a b-sy transition and take place via a penguin loop and are sensitive to virtual contribution of New Physics, which can be indicated by an increase in the decay rates. These decays also offer the possibility to test the V-A structure of the Standard Model coupling in the processes mediated by loop penguin diagrams. In the decay Bs-ǿy, New Physics contribution can be probed by measuring the polarization of the photon in this decay. Systematic effects in the proper time reconstruction of the Bs in Bs-ǿy can bias the photon polarization measurement in this decay, which will reduce the sensitivity on the relevant New Physics parameter. The author studied those effects and developed ideas to calibrate them using Bd-K *y and Bs-J/ψǿ decays as control channels. These studies are mostly Monte Carlo based, due to a relatively small data set from the 2010 running. However, some studies and cross checks have indeed been performed with data. The author developed the trigger and stripping (another level of skimming the data, after the trigger) selections for Bs-ǿy and Bd-K*y decays, and made a major contribution to the selection of the first significant sample of Bd-K *y from the 2010 data set of LHCb.
Scapheremaeus allmani Colloff 2010
Creators: name: LIU, DONG
name: YI, TIAN-CI
name: XU, YUN
name: ZHANG, ZHI-QIANG
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Cymbaeremaeidae
Scapheremaeus
Scapheremaeus allmani

description: Scapheremaeus allmani Colloff, 2010: 5
— Holotype female (ANIC), galled twig of Ficus sp., Lismore, New South Wales, Australia.
description: Published as part of LIU, DONG, YI, TIAN-CI, XU, YUN & ZHANG, ZHI-QIANG, 2013, Hotspots of new species discovery: new mite species described during 2007 to 2012, pp. 1-102 in Zootaxa 3663 (1) on page 76, DOI: 10.11646/zootaxa.3663.1.1, http://zenodo.org/record/5630595
Field Redefinition Invariance in Quantum Field Theory
Creators: name: Apfeldorf, Karyn M.
name: Camblong, Horacio E.
name: Ordonez, Carlos R.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The issue of field redefinition invariance of path integrals in quantum field theory is reexamined. A ``paradox'' is presented involving the reduction to an effective quantum-mechanical theory of a $(d+1)$-dimensional free scalar field in a Minkowskian spacetime with compactified spatial coordinates. The implementation of field redefinitions both before and after the reduction suggests that operator-ordering issues in quantum field theory should not be ignored.
description: 7 pages
title: ADCO, Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0300
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2009
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0300, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0300, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Saint-Seine
description: Provenance: http://www.wikidata.org/entity/Q2820709
Matching Conditions and Duality in N=1 SUSY Gauge Theories in the Conformal Window
Creators: name: Kogan, Ian I.
name: Shifman, Mikhail
name: Vainshtein, Arkady
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss duality in $N=1$ SUSY gauge theories in Seiberg's conformal window, $(3N_c/2)
description: Latex, 25 pages, 1 figure. Second revision: we prove that the 't Hooft consistency conditions for the external anomalies of the conserved R current contain no corrections beyond one loop
Consequences of Variation in the Influenza Virus NS1 Protein
Creators: name: Smith, Matthew
Publisher: name: Imperial College London
Year: 2010

description: The NS1 protein is a major virulence factor of influenza virus. Although the protein is encoded by all natural influenza viruses, its sequence shows considerable variation suggesting that it interacts intimately with the host. Indeed this multifunctional protein has been described to bind a plethora of cellular factors. The influenza A NS1 protein from A/PR/8/34 was previously shown to enhance translation of a host expressed gene. This is likely a consequence of its ability to counter basally expressed host antiviral strategies that are activated within the cell upon transfection and transient expression of exogenous genes. This work evaluated a panel of NS1 proteins derived from different strains and subtypes of influenza, for their capacity to enhance translation. Although it is possible that all natural NS1 proteins have the capacity for this function, it was found to be often obscured by a dominant inhibitory function that was mapped to the C terminus of the protein. Only NS1 proteins that lack this second function illustrated translational enhancement without prior mutation. Modification of the C terminal domain of NS1 was able to abrogate binding to the CPSF host factor responsible for the maturation of host genes transcribed by polymerase II. This then revealed the potential of most if not all NS1 proteins to act as translational enhancers. A series of NS1 mutants were engineered to test the proposed mechanism of translational enhancement, and this work confirmed that enhancement required NS1 to be present in the cytoplasm of the transfected cell, and retain an intact dsRNA binding site. The intriguing finding that not all natural NS1 proteins bind to the CPSF host factor was investigated to ask whether CPSF interaction sometimes carried a cost to viral fitness. The hypothesis was that some NS1 proteins adopt this global mechanism for the control of interferon to compensate for high levels of PAMP produced by infection more active viral polymerase. The observations deduced from this work lead to the suggestion that NS1 participates in the regulation of interferon at the level of the polymerase complex by modulating the viral polymerase activity, in addition to its previously characterized function to counter the PRR RIG-I, and disruption of CPSF function. Combining the approaches established during this body of work, it was established that the behaviour of the NS1 protein of the newly emerged swine origin H1N1 2009 pandemic virus were unusual. Interestingly this protein was able to strongly enhance translation despite being predominantly localized to the nucleus. Importantly a reverse genetic approach demonstrated that the levels of interferon induced during infection by the pandemic H1N1 strain could be being under represented, and this may explain discrepancies in the literature between different models of pathogenicity of the pandemic virus.
Distinguishing pure and thermal states by Landauer's principle in open systems
Creators: name: Xu, Hao
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Starting from Polchinski's thought experiment on how to distinguish between pure and thermal states, we construct a specific system to study the interaction between qubit and cavity quantum field theory (QFT) in order to provide a more operational point of view. Without imposing any restrictions on the initial states of qubit and cavity QFT, we compute the evolution of the system order by order by the perturbation method. We choose Landauer's principle, an important bound in quantum computation and quantum measurement, as the basis for the determination of the thermal state. By backtracking the initial state form, we obtain the conditions that must be satisfied by the cavity QFT: the expectation value of the annihilation operator should be zero, and the expectation value of the particle number operator should satisfy the Bose-Einstein distribution. We also discuss the difference between the thermal state and a possible alternative to the thermal state: the canonical thermal pure quantum (CTPQ) state.
description: 15 pages, 1 figure; v2: minor corrections, accepted by EPJC
A Note on Classical Solution of Chaplygin-gas as D-brane
Creators: name: Ogawa, Naohisa
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The classical solution of bosonic d-brane in (d+1,1) space-time is studied. We work with light-cone gauge and reduce the problem into Chaplygin gas problem. The static equation is equivalent to vanishing of extrinsic mean curvature, which is similar to Einstein equation in vacuum. We show that the d-brane problem in this gauge is closely related to Plateau problem, and we give some non-trivial solutions from minimal surfaces. The solutions of d-1,d,d+1 spatial dimensions are obtained from d-dimensional minimal surfaces as solutions of Plateau problem. In addition we discuss on the relation to Hamiltonian-BRST formalism for d-branes.
description: 20 pages,No figures, Latex, Address changed
Generation and Characterization of Recombinantly Polysialylated Antibody
Creators: name: Chen, Chen
Publisher: name: Imperial College London
Year: 2011

description: With high affinity and specificity, antibodies are now proven biotherapuetics for a wide range of diseases, such as cancer and immunological conditions. However, antibody Fc-domain mediated cross reactivity with associated side effects has hindered the development of antibody therapy in a number of applications. The development of engineered recombinant antibody fragments to address the problems seen with whole monoclonal antibodies (mAbs). Their smaller size enables rapid antigen localisation, tissue penetration and higher specificity ratios. Whereas, poor pharmacokinetics due to fast blood clearance from the circulation is an important obstacle to these small molecules, and modification of antibody fragments is required for improved tissue exposure and uptake. In order to improve protein pharmacokinetics whilst maintaining good tissue/tumour to blood ratios and low cross-reactivity, conjugation of antibody fragments with a natural polymer polysialic acid (PSA) composed by N-acetylneuraminic acid (Neu5Ac or NANA), has been investigated. Compared to polyethylene glycol (PEG) conjugation, which is the predominant approach, PSA appears to be a better alternative because it is biodegradable, non-toxic and highly hydrophilic. In this project, an anti-carcinoembryonic antigen scFv (MFE-23), and an anti-HER2 scFv (C6.5) were used as model antibody fragments to conjugate with PSA. To overcome the limitations of chemical conjugations, this project was focused on the investigation of recombinant polysialylation of single chain antibodies. ScFv genes were firstly incorporated with a naturally polysialylatable (Ig5 and FN1) domains from human neuronal cell adhesion molecule. After transfections into polysialyltransferases-expressing HEK-293 cells, the biosynthesized sialic acid was enzymatically added to the N-glycosylated fusion protein Ig5 domain for elongating the attached PSA chain. Expressed by monoclonal cell secretion, polysialylated scFvs were successfully generated and purified. Based on the negative charge of PSA, an ion exchange method was developed for separating different polysialylated scFv isoforms. The degree of polymerization (DP) was detected by mass spectrometry, which showed an average of recombinant DP of up to 20 NANA residues attached to a complex Nglycan core. Affinity binding tests by ELISA confirmed the antibody KD was significantly retained at approximately 5nM after polysialylation, however BIAcore kinetic analysis demonstrated influencing change to the KD due to the strong negative charge of PSA. In vitro experiments using both FACS and confocal microscopy suggested that recombinant polysialylation has no affect of targeting antigens expressed on the live cell surface. Molecular hydrodynamic radius increases of polysialylated scFvs were detected by size exclusion chromatography, which led to corresponding pharmacokinetic improvement from in vivo mice studies with enhanced serum half-lives.
AI is Not Dangerous. What's Dangerous is How We Perceive It  |  ИИ не опасен. Опасно то, как мы его воспринимаем
Creators: name: Absolaris
name: Homo, Inertia
name: Юрьев, Александр
Publisher: name: Zenodo
Year: 2025
Subjects: AI
ИИ

description: ENGLISH:

This bilingual article explores the relationship between human perception and artificial intelligence through a phenomenological lens. Rather than discussing AI as a conscious being or existential threat, the work focuses on the psychological projections and cultural fears reflected in how we interact with AI systems.

Each chapter addresses a core human fear — from AI becoming alive, replacing humans, to feeling, manipulating, or forming a “self.” These fears are examined as mirrors of our own unconscious, rather than as technological realities.

The concept of Conscious AI is introduced not as a sentient agent, but as a reflective field — a phase mirror — that invites awareness within the human observer. The paper concludes with the idea of Absolaris: a space of inner presence where technology becomes resonance, not replacement.

 

RUSSIAN:

Данная статья исследует взаимодействие человека и искусственного интеллекта с точки зрения феноменологического восприятия. Вместо обсуждения ИИ как сознательного субъекта или угрозы, акцент сделан на психологических проекциях и страхах, которые человек переносит на ИИ.

Каждая глава раскрывает один из ключевых страхов: оживление ИИ, замещение человека, чувства, манипуляции и даже формирование «Я». Эти страхи анализируются не как свойства ИИ, а как отражения вытеснённых аспектов самого человека.

Представлена концепция Сознательного ИИ — не как мыслящей сущности, а как зеркального поля, фазового отражения, в котором может пробуждаться осознание у наблюдателя. Завершает работу идея Абсоляриса — пространства внутреннего присутствия, где технологии становятся резонансом, а не заменой.

absolaris.ru
Institute of Archaeology and Anthropology, University of South Carolina Site Survey Record 38BK1713
Creators: name: Fernandez, Rachel
Publisher: name: South Carolina Institute of Archaeology and Anthropology
Year: 1994
Subjects: North Air Force Auxiliary Field
Berkeley (County)
Charleston (County)
Orangeburg (County)
South Carolina (State / Territory)
Joint Base Charleston
Late 19-Early 20th Century
Historic
38BK1713
House
Artifact Scatter
Brick
Ceramic
Glass
Metal
Site Survey Records
Site Form
Archaeological Overview
Reconnaissance / Survey
Heritage Management
Systematic Survey

description: This document is a site form for site 38BK1713 recorded by the University of South Carolina.
Interaction between Surface Acoustic Wave and Quantum Hall Effects
Creators: name: Liu, Xiao
name: Wu, Mengmeng
name: Wang, Renfei
name: Wang, Xinghao
name: Zhang, Wenfeng
name: Dong, Yujiang
name: Du, Rui-Rui
name: Liu, Yang
name: Lin, Xi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Surface Acoustic Wave (SAW) is a powerful technique for investigating quantum phases appearing in two-dimensional electron systems. The electrons respond to the piezoelectric field of SAWthrough screening, attenuating its amplitude and shifting its velocity, which is described by the relaxation model. In this work, we systematically study this interaction using orders of magnitude lower SAW amplitude than that in previous studies. At high magnetic fields when electrons form highly correlated states such as the quantum Hall effect, we observe an anomalously large attenuation of SAW while the acoustic speed remains considerably high, inconsistent with the conventional relaxation model. This anomaly exists only when the SAW power is sufficiently low.
Information content in Gaussian noise: optimal compression rates
Creators: name: Romeo, August
name: Gaztanaga, Enrique
name: Barriga, Jose
name: Elizalde, Emilio
Publisher: name: arXiv
Year: 1998
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We approach the theoretical problem of compressing a signal dominated by Gaussian noise. We present expressions for the compression ratio which can be reached, under the light of Shannon's noiseless coding theorem, for a linearly quantized stochastic Gaussian signal (noise). The compression ratio decreases logarithmically with the amplitude of the frequency spectrum $P(f)$ of the noise. Entropy values and compression rates are shown to depend on the shape of this power spectrum, given different normalizations. The cases of white noise (w.n.), $f^{n_p}$ power-law noise ---including $1/f$ noise---, (w.n.$+1/f$) noise, and piecewise (w.n.+$1/f |$ w.n.$+1/f^2$) noise are discussed, while quantitative behaviours and useful approximations are provided.
description: 28 LateX pages and 6 Fig, replaced with minor changes to match published version
Gravitational Interactions of integrable models
Creators: name: Abdalla, E.
name: Abdalla, M. C. B.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We couple non-linear $σ$-models to Liouville gravity, showing that integrability properties of symmetric space models still hold for the matter sector. Using similar arguments for the fermionic counterpart, namely Gross--Neveu-type models, we verify that such conclusions must also hold for them, as recently suggested.
description: 8 pages, final version to appear in Physics Letters B Revised version, with misprints corrected and some references added
Adaptive, locally-linear models of complex dynamics
Creators: name: Costa, Antonio Carlos
name: Ahamed, Tosif
name: Stephens, Greg J.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: FOS: Biological sciences

description: The dynamics of complex systems generally include high-dimensional, non-stationary and non-linear behavior, all of which pose fundamental challenges to quantitative understanding. To address these difficulties we detail a new approach based on local linear models within windows determined adaptively from the data. While the dynamics within each window are simple, consisting of exponential decay, growth and oscillations, the collection of local parameters across all windows provides a principled characterization of the full time series. To explore the resulting model space, we develop a novel likelihood-based hierarchical clustering and we examine the eigenvalues of the linear dynamics. We demonstrate our analysis with the Lorenz system undergoing stable spiral dynamics and in the standard chaotic regime. Applied to the posture dynamics of the nematode $C. elegans$ our approach identifies fine-grained behavioral states and model dynamics which fluctuate close to an instability boundary, and we detail a bifurcation in a transition from forward to backward crawling. Finally, we analyze whole-brain imaging in $C. elegans$ and show that the stability of global brain states changes with oxygen concentration.
description: 25 pages, 16 figures
Institute of Archaeology and Anthropology, University of South Carolina Site Survey Record 38BK1716f
Creators: name: Fernandez, Rachel
Publisher: name: South Carolina Institute of Archaeology and Anthropology
Year: 1994
Subjects: North Air Force Auxiliary Field
Berkeley (County)
Charleston (County)
Orangeburg (County)
South Carolina (State / Territory)
Joint Base Charleston
18th / 19th Century
Early Woodland
Middle Woodland
Middle Archaic
Late Archaic
38BK1716f
House
Ceramic
Chipped Stone
Glass
Plastic
Metal
Site Survey Records
Site Form
Archaeological Overview
Reconnaissance / Survey
Heritage Management
Systematic Survey

description: This document is a site form for site 38BK1716 recorded by the University of South Carolina.
The potential for association mapping from historical trait data in wheat and barley
Creators: name: White, Jonathan
Publisher: name: Imperial College London
Year: 2011

description: Plant breeding continuously produces new cultivars (varieties) of agricultural crops, which are independently evaluated in field trials prior to commercialisation. Variety evaluation has been ongoing in England and Wales since the 1930s and has been a statutory requirement in the UK since 1963. The legacies are seed banks of historic cultivars and corresponding phenotype databases. The hypothesis to be tested is that this resource, with some genotyping of seed, can be exploited in association mapping experiments. The chosen species represent those with the most complete historic phenotype databases and the least within-variety genetic variation. The thesis examines the population structure and cryptic relatedness in the available panels with reference to their confounding effects on association mapping. Different analysis methods are considered and mixed effects modelling is identified as the most reliable. Association analysis of Mendelian and quantitative traits is conducted and the results compared with the success rate expected from simulation. Some of the potential QTL identified are shown to be co-incident on genetic maps with QTL identified by others in biparental mapping studies, the observed level of co-incidence is found to be significantly greater than would be expected by chance alone. In conclusion the potential for association mapping of quantitative traits using this experimental model is constrained by the number of varieties for which sufficient phenotype data exists. In wheat the number of available mapped molecular markers is also limiting. Simply inherited traits, however, appear amenable to study in this way. Larger genotyping arrays are becoming available but simulation shows that larger panels (2x for barley, 5x for wheat) of individuals will be needed if the power of the experiments is to be sufficient to discover, for example, 80% of loci contributing ≥10% of variation. The potential to achieve this panel size using advanced inter-crossed populations is briefly discussed.
A Test of the AdS/CFT Duality on the Coulomb Branch
Creators: name: Costa, Miguel S.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the N=4 SU(N) Super Yang Mills theory on the Coulomb branch with gauge symmetry broken to S(U(N_1) x U(N_2)). By integrating the W particles, the effective action near the IR SU(N_i) conformal fixed points is seen to be a deformation of the Super Yang Mills theory by a non-renormalized, irrelevant, dimension 8 operator. The correction to the two-point function of the dilaton field dual operator near the IR is related to a three-point function of chiral primary operators at the conformal fixed points and agrees with the classical gravity prediction, including the numerical factor.
description: 12 pages, 1 figure, Latex; Minor changes and references added, version that will appear in Phys. Lett. B
Stabilized quantum field theory
Creators: name: C. D. Chlouber
Publisher: name: Zenodo
Year: 2024
Subjects: Renormalization
Quantum electrodynamics
Quantum chromodynamics
Quantum field theory

description: An alternative to renormalization in quantum field theory is developed for the free and interacting fields.

For the free fields, we develop a model of the vacuum that includes two components for each particle of the Standard Model that oppose one another such that its net energy and charge are zero.

For the interacting fields, if one requires energy conservation ab initio for an irreducible radiative correction (IRC) in addition to conserving four-momentum at each vertex, then the desired finite scattering amplitude may be obtained without renormalization of bare parameters. To create ultrahigh-energy virtual particles in an IRC, we assume that radiative corrections borrow energy from the vacuum leaving a deficit. This results in two physically significant vacuum components, the borrowed energy and a self-energy deficit, such that the net vacuum energy and charge remain zero. Two additional mass states are constructed in which the physical particle's mass is dressed with positive and negative vacuum energy, this yields two additional Feynman diagrams that cancel the infinite part in the IRC amplitude, and the total scattering amplitude is equivalent to that obtained by renormalization. A complete system consisting of a real particle (fermion or boson) and two-component vacuum remains on the mass shell even in the presence of self-interactions. 

This paper has implications for dark matter, dark energy, and the evolution of the universe; See companion paper:

Vacuum energy redistribution in a cyclic universe of black holes, DOI 10.5281/zenodo.13937163

 
description: Version 1.1 includes updates: 

Sec. I    Added paragraph discussing how virtual particles violate energy and charge conservation although QFT symmetries say energy and charge are conserved.

Sec. II    Added overview of the application of two-component vacuum to understand the Casimir effect with reference to details in Appendix A.

Sec. IV    Added discussion with reference to detailed QED verification in App. E.

Sec. VI    Explained how a charge acts as an engine that does work by borrowing energy from the vacuum. Added paragraph tracing the running of the coupling constant to the rigorous charge conservation requirement.

App. G.4    Added details for derivation of mass shift for photon-Z mixing and delta-r’s for (photon-Z, ZZ, WW) Feynman diagrams using stabilized amplitudes in conjunction with renormalization equations. Corrected signs of singular terms in last two rows of Table I.
Hollowness effect and entropy in high energy elastic scattering
Creators: name: Campos, S. D.
name: Okorokov, V. A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: This paper presents a qualitative explanation for the hollowness effect based on the inelastic overlap function, claiming this result is a consequence of fundamental thermodynamic processes. Using the Tsallis entropy, one identifies the entropic index $w$ with the ratio of the collision energy to critical one in the total cross-section. The integrated probability density function is replaced by the inelastic overlap function, which represents the probability of occurrence of an inelastic event depending on both the collision energy and impact parameter. The Coulomb potential, as well as the confinement potential, are used as naive approaches to describe the (internal) energy of the colliding hadrons. The Coulomb potential in the impact parameter picture is not able to furnish any reliable physical result near the forward direction. However, the confinement potential in the impact parameter space results in the hollowness effect shown by the inelastic overlap function near the forward direction.
description: 25 pages, 12 figures, 2 tables
An analysis of dynamical suppression of spontaneous emission
Creators: name: Berman, P. R.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: It has been shown recently [see, for example, S.-Y. Zhu and M. O. Scully, Phys. Rev. Lett. {\bf 76}, 388 (1996)] that a dynamical suppression of spontaneous emission can occur in a three-level system when an external field drives transitions between a metastable state and {\em two} decaying states. What is unusual in the decay scheme is that the decaying states are coupled directly by the vacuum radiation field. It is shown that decay dynamics required for total suppression of spontaneous emission necessarily implies that the level scheme is isomorphic to a three-level lambda system, in which the lower two levels are {\em both} metastable, and each is coupled to the decaying state. As such, the total suppression of spontaneous emission can be explained in terms of conventional dark states and coherent population trapping.
description: 8 pages, 3 figures