cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
DEFINING THE ROLE OF LYSINE ACETYLATION IN REGULATING THE FIDELITY OF DNA SYNTHESIS
Creators: name: Ononye, Onyekachi Ebelechukwu
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Plant cell and molecular biology
Animal cell and molecular biology
Biochemistry and cell biology not elsewhere classified

description: Accurate DNA replication is vital for maintaining genomic stability. Consequently, the machinery required to drive this process is designed to ensure the meticulous maintenance of information. However, random misincorporation of errors reduce the fidelity of the DNA and lead to pre-mature aging and age-related disorders such as cancer and neurodegenerative diseases. Some of the incorporated errors are the result of the error prone DNA polymerase alpha (Pol a), which initiates synthesis on both the leading and lagging strand. Lagging strand synthesis acquires an increased number of polymerase a tracks because of the number of Okazaki fragments synthesized per round of the cell cycle (~50 million in mammalian cells). The accumulation of these errors invariably reduces the fidelity of the genome. Previous work has shown that these pol a tracks can be removed by two redundant pathways referred to as the short and long flap pathway. The long flap pathway utilizes a complex network of proteins to remove more of the misincorporated nucleotides than the short flap pathway which mediates the removal of shorter flaps. Lysine acetylation has been reported to modulate the function of the nucleases implicated in flap processing. The cleavage activity of the long flap pathway nuclease, Dna2, is stimulated by lysine acetylation while conversely lysine acetylation of the short flap pathway nuclease, FEN1, inhibits its activity. The major protein players implicated during Okazaki fragment processing (OFP) are known, however, the choice of the processing pathway and its regulation by lysine acetylation of its main players is yet unknown. This dissertation identifies three main findings: 1) Saccharomyces cerevisiae helicase, petite integration frequency (Pif1) is lysine acetylated by Esa1 and deacetylated by Rpd3 regulating its viability and biochemical properties including helicase, binding and ATPase activity ii) the single stranded DNA binding protein, human replication protein A (RPA) is modified by p300 and this modification stimulates its primary binding function and iii) lysine acetylated human RPA directs OFP towards the long flap pathway even for a subset of short flaps.
Additional file 24 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 24
sj-pdf-2-car-10.1177_19476035211038749 – Supplemental material for Longitudinal Changes in Ultrasound-Assessed Femoral Cartilage Thickness in Individuals from 4 to 6 Months Following Anterior Cruciate Ligament Reconstruction
Creators: name: Lisee, Caroline
name: Harkey, Matthew
name: Walker, Zachary
name: Pfeiffer, Karin
name: Covassin, Tracey
name: Kovan, Jeffrey
name: Currie, Katharine D.
name: Kuenze, Christopher
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, sj-pdf-2-car-10.1177_19476035211038749 for Longitudinal Changes in Ultrasound-Assessed Femoral Cartilage Thickness in Individuals from 4 to 6 Months Following Anterior Cruciate Ligament Reconstruction by Caroline Lisee, Matthew Harkey, Zachary Walker, Karin Pfeiffer, Tracey Covassin, Jeffrey Kovan, Katharine D. Currie and Christopher Kuenze in CARTILAGE
sj-pdf-1-ajs-10.1177_03635465211033995 – Supplemental material for Quadriceps Tendon Versus Hamstring Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis
Creators: name: Tan, Tze Khiang
name: Subramaniam, Arjun Gopal
name: Ebert, Jay R.
name: Radic, Ross
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_03635465211033995 for Quadriceps Tendon Versus Hamstring Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis by Tze Khiang Tan, Arjun Gopal Subramaniam, Jay R. Ebert and Ross Radic in The American Journal of Sports Medicine
Additional file 11 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 11
Additional file 9 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 9
Protein Arginine Methyltransferase 5 in Castration-Resistant and Neuroendocrine Prostate Cancer
Creators: name: Wild, Elena
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Oncology and carcinogenesis not elsewhere classified

description: Prostate cancer is one of the most frequently diagnosed cancers and the second leading cause of cancer-related deaths in male population. While localized prostate cancer can be successfully treated with surgery or radiation therapy, the metastatic disease has no curable options. Metastasis can be developed as a result of failed therapy of localized cancer or present at initial diagnosis. As metastasis is the most common cause of prostate cancer-related death, developing novel approaches and improving the efficiency of existing therapies for the metastatic prostate cancer treatment will significantly improve patients’ survival.
The first-line treatment option for metastatic prostate cancer and localized prostate cancer with high risk of recurrence is androgen deprivation therapy (ADT) that decreases androgen receptor (AR) signaling. However, targeting AR signaling inevitably leads to AR reactivation and cancer progression to the castration-resistant prostate cancer (CRPC) that has no curable treatment options. Moreover, about 30% of CRPC cases progress to neuroendocrine prostate cancer (NEPC), highly aggressive and lethal type of prostate cancer.
Recently my group has shown that protein arginine methyltransferase 5 (PRMT5) functions as an activator of AR expression in hormone-naïve prostate cancer (HNPC). In this dissertation, I demonstrate that PRMT5 also functions as an epigenetic activator of AR transcription in CRPC via symmetric dimethylation of H4R3 at the AR promoter. This epigenetic activation is dependent on pICln, a PRMT5 interaction partner involved in spliceosome assembly, and independent of MEP50, the canonical cofactor of PRMT5. PRMT5 and pICln, but not MEP50, were required for the expression of AR signaling pathway genes. In clinical samples of both HNPC and CRPC, nuclear PRMT5 and pICln protein expressions were highly positively correlated with nuclear AR protein expression. In xenograft tumors, targeting PRMT5 or pICln significantly decreased tumor growth and AR expression.
Overall, this work identifies PRMT5/pICln as a therapeutic target for HNPC and CRPC treatment that needs to be further evaluated in clinical setting.
Additional file 13 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 13
Random Walking Spiders for Decentralized Learning at Edge Networks
Creators: name: Ghiglione, Federico
Publisher: name: University of Illinois Chicago
Year: 2025

description: Decentralized learning is a type of Machine Learning architecture where data is distributed among
several nodes. With this approach, each node has its own dataset, usually a fraction of the whole
dataset, and it can train a model with its own data without the need to communicate with the other
nodes.
One of the most popular algorithms used in this field is Random Walk Learning (RWL). In RWL, we have
a single model that is sent to a node chosen randomly among all the nodes in the network; the node
will train the model for a certain number of epochs( usually one epoch) and then send it to another
node chosen randomly among its neighbors which will repeat the same process.
In this way, the model can learn from different nodes during the learning process, but it faces some
challenges, such as scenarios where the data distribution among the nodes is heterogenous, leading
to accuracy issues because the accuracy could depend on the path chosen from the first node to the
last one.
A new algorithm called Random Walking Spiders(RWS) has been introduced to solve these issues. The
main difference between RWL and RWS is that in RWS, we have more models trained simultaneously
instead of just one, like in RWL.
Each model is initially sent to a random node and is trained with the local dataset, like in RWL, for a
certain number of epochs (usually one epoch). After the local training in the node, all the models are
sent to the same node, and an average of the model parameters is performed there, so every model
becomes equal to each other, and then each model is sent to a new node chosen randomly, and the
process repeats itself. The idea behind this new algorithm is to learn from more nodes simultaneously
instead of just one at a time, as in RWL.
The RWS algorithm can be implemented in two different variants: non-adaptive RWS and adaptive
RWS. The non-adaptive RWS is the process described before where the modes are trained in different
nodes, then averaged, and passed to other nodes. The adaptive-RWS is an update of the non-adaptive
case where we have just one model at the beginning since it's enough in the first epochs, while after
certain conditions are met, it is split into more models.
In order to test the algorithm, the CIFAR-10 and FASHION_MNSIT public datasets were used, the
results show the superiority of both the non-adaptive RWS and the adaptive over the RWL algorithm in
terms of accuracy. While the non-adaptive RWS is better in the long term, the adaptive RWS is better
also in short-medium scenarios. This performance improvement makes this algorithm a significant
advancement in the decentralized learning field.
No human subjects were used to accomplish this task.
The role of ADF and cofilin in auditory sensory cell development
Creators: name: McGrath, Jamis
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Biochemistry and cell biology not elsewhere classified
Evolution of developmental systems
Plant cell and molecular biology
Animal cell and molecular biology

description: Our ability to hear relies on sensory cells found in the inner ear that transduce sound into biological signals. Microvilli-like protrusions called stereocilia are bundled on the apical surfaces of these cells and allow them to respond to sound-evoked vibrations. The architecture of the stereocilia bundle is highly patterned to ensure normal hearing. Filaments of polymerized actin proteins are bundled in parallel into large cylindrical structures that define the dimensions of stereocilia. This network is then anchored to the cell by inserting into another actin-based structure called the cuticular plate, which forms a gel-like structure and facilitates the mechanical properties of the bundle. The shape of the bundle is determined through tissue-level and intrinsic polarization signaling pathways. Auditory brainstem-evoked response testing, immunofluorescence imaging, scanning electron microscopy, and biochemical labeling techniques were used to study how the ADF/cofilin family of actin filament severing and depolymerizing proteins contributes to the development of the stereocilia bundle. Loss of these proteins disrupts the normal bundle patterning process, changes the lengths and widths of stereocilia, and alters the regulation of filament ends near the ion channel at stereocilia tips that is responsible for mechanotransduction. The activity of this channel regulates ADF/cofilins and the actin at stereocilia tips. Aberrant actin growth in actin networks beneath the stereocilia bundle influences the bundle patterning process, causes dysmorphic bundles to form. This work identifies that ADF/cofilins are necessary during auditory sensory cell development to facilitate normal bundle patterning and establishes this protein family as a molecular link between mechanotransduction and stereocilia bundle maturation.
Additional file 16 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 16
Needs Assessment of Food Safety Education for Small-Scale Farmers
Creators: name: Chen, Han
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Food sciences not elsewhere classified

description: Small-scale farms, as an important component of the food system in the United States, share the responsibility to ensure food safety and maintain public health. Thus, farmers play critical roles in managing and minimizing food safety risks. With increasing food safety regulatory requirements, small-scale farmers are struggling to balance between making more profits and complying with the regulation. In order to increase profits, value-added processing is getting attention among farmers. However, further processing activities trigger additional regulatory requirements, which could limit farmers’ ability to implement. Farmer food safety education is an essential approach to raise farmers’ food safety awareness and address their barriers to complying with the regulatory requirements. This thesis started from a literature review and needs assessment; then identified their barriers and needs to food safety education; lastly, dived into intervention evaluation to understand farmers’ food safety knowledge, attitudes, and practice change.In the literature review (chapter 1) and needs assessment (chapter 2) stage, small-scale produce farmers were targeted. Forty-two published articles were reviewed to understand growers’ knowledge, attitudes, and practices toward on-farm food safety principles and evaluate the effectiveness of food safety education programs for growers. A combination of qualitative and quantitative methods was used to assess growers’ food safety education needs and identify their motivators and barriers to starting and expanding a value-added business. In the intervention evaluation (chapter 3) stage, the military veteran farmer group was targeted. The effectiveness of three educational interventions, including learning circles, in-person workshops, and electronic newsletters, was evaluated by using pre- and post-surveys.The findings from the research showed that farmers were aware of the importance of food safety, but their knowledge and risk perceptions were insufficient. They commonly lacked time to do additional activities other than farming such as learning and adopting new practices or involving in value-added processing. Most food safety education programs were reported to improve farmers’ knowledge. However, farmers still perceived standardized food safety education programs to be burdensome and were expecting to receive culturally tailored education programs targeted at small-scale farmers. These findings provide the foundation for the development of future education programs for small-scale farmers.
Additional file 18 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 18
Variational Inference with Theoretical Guarantees
Creators: name: Bai, Jincheng
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Statistics not elsewhere classified

description: Variational inference (VI) or Variational Bayes (VB) is a popular alternative to MCMC, which doesn't scale well on complex Bayesian learning tasks with large datasets. Despite its huge empirical successes, the statistical properties of VI have not been carefully studied only until recently. In this dissertation, we are concerned with both the implementation and theoretical guarantee of VI.
In the first part of this dissertation, we propose a VI procedure for high-dimensional linear model inferences with heavy tail shrinkage priors, such as student-t prior. Theoretically, we establish the consistency of the proposed VI method and prove that under the proper choice of prior specifications, the contraction rate of the VB posterior is nearly optimal. It justifies the validity of VB inference as an alternative of MCMC sampling. Meanwhile, comparing to conventional MCMC methods, the VI procedure achieves much higher computational efficiency, which greatly alleviates the computing burden for modern machine learning applications such as massive data analysis. Through numerical studies, we demonstrate that the proposed VI method leads to shorter computing time, higher estimation accuracy, and lower variable selection error than competitive sparse Bayesian methods.
In the second part of this dissertation, we focus on sparse deep learning, which aims to address the challenge of huge storage consumption by deep neural networks, and to recover the sparse structure of target functions. We train sparse deep neural networks with a fully Bayesian treatment under two classes spike-and-slab priors, and develop sets of computationally efficient variational inferences via continuous relaxation of Bernoulli distribution. Given a pre-specified sparse DNN structure, the corresponding variational contraction rate is characterized that reveals a trade-off between the statistical estimation error, the variational error, and the approximation error, which are all determined by the network structural complexity (i.e., depth, width and sparsity). Note that the optimal network structure, which strikes the balance of the aforementioned trade-off and yields the best rate, is generally unknown. However, our methods could always achieve the best contraction rate as if the optimal network structure is known. In particular, when the true function is Hölder smooth, the variational inferences are capable to attain nearly minimax rate without the knowledge of smoothness level. In addition, our empirical results demonstrate that the variational procedures provide uncertainty quantification in terms of Bayesian predictive distribution and are also capable to accomplish consistent variable selection by training a sparse multi-layer neural network.
sj-docx-2-taj-10.1177_20406223211039696 – Supplemental material for Endoscopic treatment for gastric antral vascular ectasia
Creators: name: Peng, Mengyuan
name: Guo, Xiaozhong
name: Yi, Fangfang
name: Shao, Xiaodong
name: Wang, Le
name: Wu, Yanyan
name: Wang, Chunmei
name: Zhu, Menghua
name: Bian, Ou
name: Ibrahim, Mostafa
name: Chawla, Saurabh
name: Qi, Xingshun
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Respiratory Diseases

description: Supplemental material, sj-docx-2-taj-10.1177_20406223211039696 for Endoscopic treatment for gastric antral vascular ectasia by Mengyuan Peng, Xiaozhong Guo, Fangfang Yi, Xiaodong Shao, Le Wang, Yanyan Wu, Chunmei Wang, Menghua Zhu, Ou Bian, Mostafa Ibrahim, Saurabh Chawla and Xingshun Qi in Therapeutic Advances in Chronic Disease
Additional file 8 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 8
Exploring the population dynamics of wintering bald eagles through long-term data
Creators: name: Dangremond, Emily
name: Beckstead, Julie
name: Lagasse, Alexandra
name: Robinson, Scott
Publisher: name: QUBES Educational Resources
Year: 2018

description: Module included in Teaching Issues and Experiments in Ecology (TIEE) Volume 7
Students will identify dependent and independent variables, create graphs of dependent variables plotted against independent variables and evaluate  long-term eagle...
A Psychological Needs Framework for Refugee Integration in the Workplace
Creators: name: Li, Sharon
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Industrial and organisational psychology (incl. human factors)
Behavioural neuroscience
Applied and developmental psychology not elsewhere classified

description: In the face of an increasingly pressing refugee crisis, host organizations have become a key context for refugee integration (Bimrose & McNair, 2011). Successful integration is critical to refugees’ well-being. However, our theoretical understanding of this process is still limited. This is partly because research centering on refugees is scarce, and the literature lacks a unifying framework to explain how varied integration practices could address refugee needs. To address this gap, the current study applies self-determination theory (SDT) to systematically understand how organizational practices may support refugees’ autonomy, competence, and relatedness needs. To do so, I examine refugee (vs. non-refugee) perceptions of organizational support helpfulness and explore its underlying processes (e.g., needs deprivation, work centrality). Findings suggest that refugees tend to view autonomy and relatedness practices as especially helpful, and these relationships are mediated through higher work centrality. I conclude with a discussion of the theoretical and practical implications of the findings for refugee workplace integration.
THREE ESSAYS ON FARMLAND INVESTMENT
Creators: name: Noumir, Ashraf M
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Agricultural economics
Financial economics

description: This dissertation is comprised of three essays focusing on farmland economics with particular attention to characterizing risk and return of farmland investment. The first essay in chapter two discusses the portfolio performance of different farmland qualities in different geographic regions in two Corn Belt states, namely Indiana and Iowa. I found that risk of different farmland qualities in different geographic regions are low compared to other assets. Excess return, however, is higher and statistically significant in Indiana relative to Iowa. Results also suggest that diversifying across farmland locations and qualities contributes positively to farmland investment in Indiana but not in Iowa. The second essay in chapter three examines whether farmland has a risk factor in asset pricing models. In other words, I examine whether the additional return of farmland investment is associated with additional risk. Relying on the National Council of Real Estate Investment Fiduciaries (NCREIF) farmland property index and U.S. stock returns, I show that exposure to farmland risk has neither economical nor statistical explanatory power for the expected stock returns across a range of equity portfolios. In the third essay in chapter four, I develop a decision rule to determine the optimal mix of owned and rented farmland operated by a farmer or agricultural investor. I do so by extending portfolio theory to get the optimal mix of owned and rented farmland that minimize farming risk. Utilizing data on West Central Indiana, this portfolio rule shows that owning is far more attractive than renting farmland. Chapter five concludes the three essays.
The Robot Architecture Framework - A systematic approach for describing the architecture of complex, autonomous robotic systems.
Creators: name: Dömel, Andreas
Publisher: name: Staats- und Universitätsbibliothek (SuUB) Bremen
Year: 2025
Subjects: Robot Architecture
Architecture Framework
Autonomous Robots

description: Many autonomous robots are currently designed based on the system architect’s individual experience and knowledge, taking into account given factors such as application and environment. The complexity of robots, but also the diversity of systems, applications and fields of use, make it difficult to compare these individual solutions and to transfer architectural approaches to new system designs. This thesis answers the research question of how the knowledge about robot architecture contained in existing systems can be made accessible. The developed process enables the systematic capturing of the architecture of autonomous robot systems. The resulting structured architecture descriptions make it possible to identify similarities and differences in the architectures of different systems despite the complexity and heterogeneity of robots. The methodology chosen is an extension of the Architecture Framework concept. This approach, which originates from the field of software development, is used to capture the architectures of distributed software systems. This work transfers and extends the approach to the domain of robotics by defining a Robot Architecture Framework. The architecture description process based on this framework enables the architecture of existing robotic systems to be identified. The applicability of the process is demonstrated using three very different robotic systems. It is shown that compact architecture descriptions can be generated despite the complexity and heterogeneity of the systems. In addition, the broad applicability of the defined process is also conceptually validated.
Additional file 22 of Experiences of postpartum mental health sequelae among black and biracial women during the COVID-19 pandemic
Creators: name: Dwarakanath, Megana
name: Hossain, Fahmida
name: Balascio, Phoebe
name: Moore, Mikaela C.
name: Hill, Ashley V.
name: De Genna, Natacha M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Mental Health
Computational Biology

description: Supplementary Material 22
MULTI-THRESHOLD LOW POWER-DELAY PRODUCT MEMORY AND DATAPATH COMPONENTS UTILIZING ADVANCED FINFET TECHNOLOGY EMPHASIZING THE RELIABILITY AND ROBUSTNESS
Creators: name: Yadav, Avinash
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Circuits and systems

description: In the era of high-speed circuits and systems, CMOS technology has reached its limits. The balance of power, performance, and area trade-off is the base of current digital systems. Industries are designing chips at the cutting-edge technologies using 3nm, 5nm, 7nm, and 10nm processes. These advanced node technologies allow to efficiently direct the flow of electrons making the high-performance low-power devices physically possible. The aforementioned Power Performance Area (PPA) trade-off varies significantly for different applications. Moreover, semiconductor device parameters vary with the process and environmental variations that are modeled under term Process, Voltage, and Temperature (PVT). A satisfactory PVT operating conditions ensure the good behavior of the circuit for the desired application.
In this thesis, we investigated the 7 nm FinFET technology for its delay-power product performance. In our study, we explored the ASAP7 library from Arizona State University, developed in collaboration with ARM Holdings. The FinFET technology was chosen since it has a subthreshold slope of 60mV/decade that enables cells to function at 0.7V supply voltage at the nominal corner. An emphasis was focused on characterizing the Non-Ideal effects, delay variation, and power for the FinFET device. An exhaustive analysis of the INVx1 delay variation for different operating conditions was also included, to assess the robustness.
The 7nm FinFET device was then employed into 6T SRAM cells and 16 function ALU. The SRAM cells were approached with advanced multi-corner stability evaluation. The system-level architecture of the ALU has demonstrated an ultra-low power system operating at 1 GHz clock frequency. The ALU design introduces an Intellectual Property (IP) characterized by different PVT corners suitable for Low power, machine learning, embedded systems, and other complex computer arithmetic applications. Each of the circuit and system represents significant speedup over planar CMOS technologies and contributes to the field of Ultra Large Scale of Integrated Circuit (ULSI) design.
The 7 nm FinFET device explored as the minimum threshold voltage of 207mV, maximum effective current of 18.26 µA, and maximum power consumption of 14.75 µW with high speed measured via multi-corner simulation. A comparative study between the various advanced technologies was introduced to designate the unique features of the FinFET system technology.
The successful design and simulation of the SRAM cells led to a robust design for the L2/L3 caches that may feature high-performance microprocessors. A complete FinFET CPU integrating more instructions is reserved for future considerations.
sj-docx-3-taj-10.1177_20406223211039696 – Supplemental material for Endoscopic treatment for gastric antral vascular ectasia
Creators: name: Peng, Mengyuan
name: Guo, Xiaozhong
name: Yi, Fangfang
name: Shao, Xiaodong
name: Wang, Le
name: Wu, Yanyan
name: Wang, Chunmei
name: Zhu, Menghua
name: Bian, Ou
name: Ibrahim, Mostafa
name: Chawla, Saurabh
name: Qi, Xingshun
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Respiratory Diseases

description: Supplemental material, sj-docx-3-taj-10.1177_20406223211039696 for Endoscopic treatment for gastric antral vascular ectasia by Mengyuan Peng, Xiaozhong Guo, Fangfang Yi, Xiaodong Shao, Le Wang, Yanyan Wu, Chunmei Wang, Menghua Zhu, Ou Bian, Mostafa Ibrahim, Saurabh Chawla and Xingshun Qi in Therapeutic Advances in Chronic Disease
title: A Markedly Different Approach
title: Investigating PIE Stops Using Modern Empirical Methods
titleType: Subtitle
Creators: name: Barnett, Phillip
Publisher: name: University of Kentucky Libraries
Year: 2018
Subjects: subject: Comparative and Historical Linguistics
subject: Computational Linguistics
subject: Phonetics and Phonology

description: In this thesis, I investigate a decades-old problem found in the stop system of Proto-Indo-European (PIE). More specifically, I will be investigating the paucity of */b/ in the forms reconstructed for the ancient, hypothetical language. As cross-linguistic evidence and phonological theory alone have fallen short of providing a satisfactory answer, herein will I employ modern empirical methods of linguistic investigation, namely laboratory phonology experiments and computational database analysis. Following Byrd 2015, I advocate for an examination of synchronic phenomena and behavior as a method for investigating diachronic change.

In Chapter 1, I present an overview of the various proposed phonological systems of PIE and some of the explanations previously given for the enigmatic rarity of PIE */b/. Chapter 2 presents a detailed account of three lab phonology experiments I conducted in order to investigate perceptual confusability as a motivator of asymmetric merger within a system of stop consonants. Chapter 3 presents the preliminary form and findings of a computational database of reconstructed forms in PIE that I created and have named the Database of Etymological Reconstructions Beginnning in Proto-Indo-European (DERBiPIE). The final chapter, Chapter 4, offers a summary of the work presented herein and conclusions that may be drawn, offering suggestions for continued work on the topic and others like it.
"If we can't grow rice, then what?": Farming Livelihoods in the Production of Vietnam's Rice Farming Landscapes
Creators: name: Huang, Sarah D
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Anthropology not elsewhere classified

description: This dissertation challenges dominant food security discourses and practices that seek to address food insecurity through technoscientific approaches to agricultural production. Situated in Vietnam’s An Giang province in the Mekong River Delta, this work ethnographically explores and historically grounds global, national, and household scalar implications of these same discourses and practices on rice farmers’ livelihoods. The central research question that guided this project asks: if farmers are producing security for the nation, then why do they remain food insecure? Through a 16-month ethnographic study utilizing a mixed-methods approach I combined participant observation, household surveys, semi-structured interviews, and participatory mapping with rice farmers, farm laborers, and local and national government officials in order to address this question from a historically and ethnographically ground perspective. I show how Vietnam’s history of hunger and famine, experienced most recently in the late 1970’s, colors the nation’s current and future agricultural development. Focused on a future of rural development, economic growth, and values of modernity, new models of agricultural production are implemented across the Mekong River Delta to ensure the nation’s self-sufficiency in producing “enough” rice and food. Amongst these strategies, intensive triple cropping rice practices, food safety certifications and practices, and an increased reliance on agro-chemicals has resulted in differing farming practices and mixed impacts on farming livelihoods. I leverage a feminist political ecology and science and technology studies framework to foreground the rice farmers’ perspectives and differed experiences, while tracking the rooted inequalities within government policies, market logics, and social relationships. In three articles, I (1) examine differential experiences of state-based agricultural models and their impact on farmers’ livelihood security (2) trace how dominant discourses raise questions about individual and state responsibility; and (3) explore emergent farming livelihood opportunities and challenges within late socialist agricultural development. Drawing on ethnographic accounts and experiences, particularly from farmers, results showed that these dominant discourses that narrows food security to only be governable through techno-scientific approaches and agricultural practices are insufficient to address farmers’ insecurity.
Additional file 1 of The effect of a digital-assisted group rehabilitation on clinical and functional outcomes after total hip and knee arthroplasty—a prospective randomized controlled pilot study
Creators: name: Osterloh, Judith
name: Knaack, Franziska
name: Bader, Rainer
name: Behrens, Martin
name: Peschers, Juliana
name: Nawrath, Lisa
name: Bergschmidt, Philipp
name: Darowski, Martin
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health

description: Additional file 1. Appendix - Additional file 1 contains a list of physiotherapy exercises performed during the intervention. It is divided into therapy session procedure, warm-up exercises, main exercises following hip or knee arthroplasty, and cool-down exercises.
title: 2. Bericht des Bundesministeriums der Verteidigung zu Rüstungsangelegenheiten. Teil 1
Creators: name: (:Unav)
Publisher: name: Bundesministerium der Verteidigung
Year: 2025
Subjects: subject: 355 Militärwissenschaft

description: Der Rüstungsbericht des BMVg informiert im Rahmen des Risikomanagements über den Entwicklungsstand von 19 relevanten Rüstungsprojekten. Der Fokus liegt auf dem Jahr 2016. Dieser Bericht erläutert auch die im Verhältnis zu 2015 veränderte Systematik hinsichtlich des Formats und der Inhalte der Projektstatusberichte. Der Bericht gliedert sich in einen offenen Teil eins und einen VS-Teil zwei. Der vorliegende offene Teil eins fasst in Kapitel eins die Gesamtlage "Rüstungswesen" einschliesslich ausgewählter vertiefender Themen zur Erläuterung zusammen. Letztere befassen sich mit der Zulassung militärischer Luftfahrzeuge, mit der Personalsituation im BAAINBw (Bundesamt für Ausrüstung, Informationstechnik und Nutzung der Bundeswehr) und mit Haushaltsaspekten. Kapitel zwei enthält "Projektbezogene Informationen" auf Basis der aktuellen Projektstatusberichte wesentlicher Rüstungsprojekte.
description: Bericht des Bundesministeriums der Verteidigung zu Rüstungsangelegenheiten. Teil 1; 2.
STAKEHOLDER PERCEPTIONS OF THE VIABILITY OF A FULLY REMOTE APPRENTICESHIP DELIVERY SYSTEM PRE-COVID-19 WITH UPDATES MID-PANDEMIC—A QUALITATIVE EXPLORATORY STUDY
Creators: name: Krause, Terri Sue
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Educational technology and computing
Human resources management
Technology management
Innovation management
Other education not elsewhere classified
Education systems not elsewhere classified
Logistics
Supply chains

description: This study explores the perceptions of critical stakeholders as to the viability of a fully remote apprenticeship delivery system (FRADS), as well as its ability to serve as a functionally equivalent path of inclusion for access-limited populations. One of the first recorded pedagogical models, apprenticeship was also one of the first to be regulated. The effectiveness of the method of training a novice to enter the adult world of work through apprenticeship is undisputed, when it is conducted in a manner approximate to that from which it derived: a process that occurs over time, with continuous interaction between novice and expert. Despite millennia of practice, and a few emerging programs called Virtual Apprenticeships, the critical real-time skills-based mentoring component (on the job instruction/training, or OJI/OJT) of the modern apprenticeship is still only carried out fully in face-to-face programs. With the move to work-from-home (WFH) resulting from the global COVID-19 pandemic of 2020, assessing the viability of a FRADS is timely. This qualitative exploratory study is a first step in the discussion. Bounded by the parameters of the U.S. Certified Apprenticeship Guidelines for Registered Apprenticeships and the constructs of viability and functional equivalence, participants of three critical stakeholder groups—policy makers, service managers, and front-line service workers—offer their pre-pandemic perceptions of the construct of a FRADS. Guided by the work of Jahoda, et al., (1957), Northrop (1949,1959), and Swedberg (2018), this qualitative exploratory methodology identified perceptual data points that are then compared against a framework of viability derived from IEG’s Service Delivery Evaluation Framework (Caceres, et al., 2016). And, because this represents a large systems change (LSC), I included aspects of Weiner’s (2009) Organizational Readiness for Change—valance and efficacy—as additional indicators of potential viability. Stakeholders examined key components of IEG’s evaluative criteria applied to a face-to-face apprenticeship as a functionally equivalent, technology-mediated apprenticeship delivery system. Additional stakeholder perceptions, mid-pandemic, along with a review of scholarly articles, media reports, and Department of Labor statistics concerning the impact of the WFH mandates foreground the gap a purposeful FRADS might fill. Analysis of some of the findings are represented in a preliminary process map.
Modeling of Electrochemical Oxidation of Contaminants in Porous Flow-Through Electrodes
Creators: name: Khalid, Yusra Sultana
Publisher: name: University of Illinois Chicago
Year: 2025

description: This work developed a reactive-transport model to simulate electrochemical oxidation for water treatment applications. Newton’s method using finite difference was used to approximate the permeate concentrations, local overpotentials, and current densities of the equations. The electrochemical oxidation of perfluoroalkyl substances (PFAS) in porous flow-through electrodes was simulated, specifically perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS). A sensitivity analysis was performed to understand the effects of material and operating parameters on the removal of PFOA and PFOS along with the energy consumption. The parameters that related to electrode area (i.e., specific surface area, electrode thickness) had considerable sensitivity to performance metrics such as permeate concentration and energy consumption. Therefore, the sensitivity analysis could be used to determine the trade-offs between the material and operating parameters and the performance metrics.
The reactive-transport model, experimental data, and density functional theory (DFT) simulations were used as a guide to understand and simulate the electrochemical oxidation pathways of wastewater contaminated with insensitive high explosives (IHEs), which included 2,4-dinitroanisole (DNAN), 3-nitro-1,2,4-triazol-5-one (NTO), and nitroguanidine (NQ). This was achieved by proposing mechanisms that described the degradation of PFAS and IHEs, implementing the mechanisms into the model, and using calibration of the model to experimental data to gain a better understanding of the probable oxidation pathways. The model included the generation of hydroxyl radicals (OH^•) and formation of reactive chlorine species (RCSs) because they played a role in the oxidation pathways of DNAN, NQ, and NTO. It was found that DNAN and NTO underwent direct electron transfer and reacted with OH^•. The oxidation of NQ led to polymerization reactions that caused blocking of the electrode surface but were reduced in the presence of NaCl due to reactions with RCSs. Obtaining a better understanding of the oxidation pathways of the IHEs will improve the model’s ability to act as a useful tool in remediating IHE-contaminated wastewater at Department of Defense sites.
sj-pdf-1-asq-10.1177_00018392211038505 – Supplemental material for Unpacking the Status-Leveling Burden for Women in Male-Dominated Occupations
Creators: name: Cardador, M. Teresa
name: Hill, Patrick L.
name: Salles, Arghavan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material, sj-pdf-1-asq-10.1177_00018392211038505 for Unpacking the Status-Leveling Burden for Women in Male-Dominated Occupations by M. Teresa Cardador, Patrick L. Hill and Arghavan Salles in Administrative Science Quarterly
title: 3. Bericht des Bundesministeriums der Verteidigung zu Rüstungsangelegenheiten. Teil 1
Creators: name: (:Unav)
Publisher: name: Bundesministerium der Verteidigung
Year: 2025
Subjects: subject: 355 Militärwissenschaft

description: Der Rüstungsbericht des BMVg informiert im Rahmen des Risikomanagements über den Entwicklungsstand von über 20 aktuellen Projekten. Der Fokus liegt auf den prägenden Ergebnissen des Jahres 2015 sowie auf dem im Jahr 2015 Erreichten, und zwar hinsichtlich der wichtigsten finanziellen Parameter und der Projektfortschritte. Der Bericht gliedert sich in einen offenen Teil eins und einen VS-Teil zwei. Der vorliegende offene Teil eins fasst in Kapitel eins die Gesamtlage "Rüstungswesen" zusammen, beginnend mit dem Umfang und dann die Entwicklung und Modernisierung beschreibend. Kapitel zwei enthält "Projektbezogene Informationen" auf Basis der aktuellen Statusberichte wesentlicher Rüstungsprojekte. Hier geht der Bericht auf Zeit und Finanzen im Vergleich zum ursprünglichen Projektansatz ein, hauptsächlich auf die Realisierungsphase und Nutzungsphase bezogen. Einige wenige Projekte befinden sich in der Phase der Angebotsaufforderung.
description: Bericht des Bundesministeriums der Verteidigung zu Rüstungsangelegenheiten. Teil 1; 3.
title: Semiring Structures of Some Classes of Hypercodes
Creators: name: Wang, Zhixi
name: Liang, Feixiang
name: He, Yong
name: Yang, Di
Publisher: name: Institut für Informatik, Justus-Liebig-Universität Giessen
Year: 2009

description: An idempotent semiring is called an incline if it satisfies the identity $1 + x=x$. The
class of inclines is a variety of semirings with the variety of c-semirings as a subvariety.
Let $A^*$ be the free monoid on an alphabet $A$, and let $\leq_h$ be the embedding order on
$A^*$. Then, as the algebra of independent subsets of the ordered monoid $(A^*,\leq_h)$, the
set $H(A)$ of hypercodes on $A$ forms a free incline. Furthermore, some subsets $H_\mathrm{c}(A)$
and $H_\mathrm{mic}(A)$ of $H(A)$ can be constructed as a free c-semiring and a free multiplicatively
idempotent c-semiring, respectively.
description: Journal of Automata, Languages and Combinatorics, Volume 14, Numbers 3-4, 2009, 259-272
title: 4. Bericht des Bundesministeriums der Verteidigung zu Rüstungsangelegenheiten. Teil 1
Creators: name: (:Unav)
Publisher: name: Bundesministerium der Verteidigung
Year: 2025
Subjects: subject: 355 Militärwissenschaft

description: Der Rüstungsbericht des BMVg informiert im Rahmen des Risikomanagements über den Entwicklungsstand von aktuellen Projekten. Der Fokus liegt auf den prägenden Ergebnissen des Jahres 2015 und den bestehenden Herausforderungen, und zwar hinsichtlich der wichtigsten finanziellen Parameter und der Projektfortschritte. Der Bericht gliedert sich in einen offenen Teil eins und einen VS-Teil zwei. Der vorliegende offene Teil eins fasst in Kapitel eins die Gesamtlage "Rüstungswesen" zusammen. Dieser Überblick zeigt ua die Organisationsstruktur des Rüstungsbereiches auf sowie Schwerpunktthemen, zB die luftgestützte Überwachung und KDL-Projekte (Komplexe Dienstleistungen der Bundeswehr). Kapitel zwei enthält "Projektbezogene Informationen" Hier geht der Bericht auf Zeit und Finanzen von 19 ausgewählten Rüstungsprojekten ein, im Vergleich zum ursprünglichen Projektansatz, hauptsächlich auf die Realisierungsphase und Nutzungsphase bezogen. Diese Informationen basieren auf den für das Rüstungsboard erarbeiteten Projektstatusberichten.
description: Bericht des Bundesministeriums der Verteidigung zu Rüstungsangelegenheiten. Teil 1; 4.