cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Implication of the Mediterranean diet on the human epigenome
Creators: name: Kenanoglu, Sercan
name: Gokce, Nuriye
name: Akalin, Hilal
name: Ergoren, Mahmut Cerkez
name: Beccari, Tommaso
name: Bertelli, Matteo
name: Dundar, Munis
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2022

description: Epigenetics, defined as “hereditary changes in gene expression that occur without any change in the DNA sequence”, consists of various epigenetic marks, including DNA methylation, histone modifications, and non-coding RNAs. The epigenome, which has a dynamic structure in response to intracellular and extracellular stimuli, has a key role in the control of gene activity, since it is located at the intersection of cellular information encoded in the genome and molecular/chemical information of extracellular origin. The focus shift of studies to epigenetic reprogramming has led to the formation and progressive importance of a concept called “nutriepigenetics”, whose aim is to prevent diseases by intervening on nutrition style. Among the diet types adopted in the world, the renowned Mediterranean Diet (MD), being rich in unsaturated fatty acids and containing high levels of whole grain foods and large quantities of fruits, vegetables, and legumes, has shown numerous advantages in excluding chronic diseases. Additionally, the fact that this diet is rich in polyphenols with high antioxidant and anti-inflammatory properties has an undeniable effect in turning some cellular pathways against the disease. It is also apparent that the effects of polyphenols on the epigenome cause changes in mechanisms such as DNA methylation and histone acetylation/deacetylation, which have a regulatory effect on gene regulation. This review presents the effects of long-term consumption of nutrients from the MD on the epigenome and discusses the benefits of this diet in the treatment and even prevention of chronic diseases.
description: Journal of Preventive Medicine and Hygiene, Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods
Orientational transition in nanobridges of nematic liquid crystals in slit pores
Creators: name: Romero-Enrique, J. M.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: In this work, the morphology of nematic capillary nanobridges in slit pores separated by a vertical distance $D$ will be characterised by Monte Carlo simulations for oblate molecules nematogen modelled by the Gay-Berne potential. Previous studies on droplets show that the molecules are arranged homeotropically at the nematic-vapour interface and form spherical droplets with an annular disclination located in their equatorial plane. In the presence of pores with attractive substrates that favour homeotropic anchoring, the formation of nanobridges characterised by anchoring angles that decrease with increasing particle-substrate interaction intensity is observed. When the orientational field in the nanobridge is analysed, the formation of an annular disclination of topological charge $+1/2$ located in the plane perpendicular to the $z$-axis that passes through the centre of mass of the nanobridge is observed for small $D$. However, when considering higher values of $D$, a change to a biaxial orientational profile within the nanobridge is observed, where now the annular disclination is arranged in a plane perpendicular to one direction of the $xy$ plane. These results are indicative of the existence of an orientational phase transition for an intermediate $D$ value between a uniaxial and a biaxial orientational configuration in the capillary nanobridge.
description: 20 pages, 8 figures. This article has been accepted for publication in Liquid Crystals, published by Taylor & Francis
Foods of the Mediterranean diet: Lacto-fermented food, the food pyramid and food combinations
Creators: name: Medori, Maria Chiara
name: Naureen, Zakira
name: Bonetti, Gabriele
name: Aquilanti, Barbara
name: Velluti, Valeria
name: MAtera, Giuseppina
name: Iaconelli, Amerigo
name: Bertelli, Matteo
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2022

description: The Mediterranean diet proved to be one of the healthiest diets in the word. It has several beneficial effects and it prevents many non-communicable diseases, such as cancer, cardiovascular diseases, and obesity. Before being a culinary regime, the Mediterranean diet is characterized by specific cultural heritages and traditions, also influencing the lifestyle of the populations. The Mediterranean diet follows the so-called food pyramid, comprising several food combinations. Indeed, it is mainly composed by vegetables, fish and dairy products, while red meat and sweets are poorly consumed. Processed foods are mainly avoided, apart from lacto-fermented ones, the first processed foods consumed by humans. Food fermentation by microorganisms not only improves the functionality of bioactive metabolites, but also increases the shelf life and organoleptic properties of the food. Lactic acid bacteria play a vital role in transforming the food constituents, thereby enhancing their nutritional and functional properties. In addition, these foods introduce beneficial bacteria into gut microbiota, thus maintaining a healthy gut microbiome and corresponding gut-brain axis, thus providing an overall improvement in health and a reduced risk of non-communicable diseases and metabolic disorders. This review will focus on the Mediterranean diet, on its characterising food pyramid and food combinations, and on lacto-fermented foods, one of the components of the Mediterranean diet with the most beneficial effects.
description: Journal of Preventive Medicine and Hygiene, Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods
Living on the edge : ground-state selection in quantum spin-ice pyrochlores
Creators: name: Yan, Han
name: Benton, Owen
name: Jaubert, Ludovic D. C.
name: Shannon, Nic
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The search for new quantum phases, especially in frustrated magnets, is central to modern condensed matter physics. One of the most promising places to look is in rare-earth pyrochlore magnets with highly-anisotropic exchange interactions, materials closely related to the spin ices Ho2Ti2O7 and Dy2Ti2O7. Here we establish a general theory of magnetic order in these materials. We find that many of their most interesting properties can be traced back to the accidental degeneracies where phases with different symmetry meet. These include the ordered ground state selection by fluctuations in Er2Ti2O7, the dimensional-reduction observed in Yb2Ti2O7, and the absence of magnetic order in Er2Sn2O7.
description: A long-paper version of this preprint, "Living on the Edge", appears as arXiv:1603.09466 [accepted for publication in Physical Review B]. The text of v2 is otherwise unchanged from v1 (Submitted on 14 Nov 2013)
title: Das Grabungsschutzgebiet „Versteinerungen Holzmaden"
Creators: name: Wagner, Eberhard
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 8, Nr. 4 (1979), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Thin shell dynamics in Lovelock gravity
Creators: name: Guilleminot, Pablo
name: Merino, Nelson
name: Olea, Rodrigo
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study matching conditions for a spherically symmetric thin shell in Lovelock gravity which can be read off from the variation of the corresponding first-order action. In point of fact, the addition of Myers' boundary terms to the gravitational action eliminates the dependence on the acceleration in this functional and such that the canonical momentum appears in the surface term in the variation of the total action. This procedure leads to junction conditions given by the discontinuity of the canonical momentum defined for an evolution normal to the boundary. In particular, we correct existing results in the literature for the thin shell collapse in generic Lovelock theories, which were mistakenly drawn from an inaccurate analysis of the total derivative terms in the system.
Foods of the Mediterranean diet: citrus, cucumber and grape
Creators: name: DHULI, KRISTJANA
name: Naureen, Zakira
name: Donato, Kevin
name: Aquilanti, Barbara
name: Velluti, Valeria
name: Matera, Giuseppina
name: Iaconelli, Amerigo
name: Bertelli, Matteo
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2022

description: Fruit and vegetables are excellent sources of health-promoting bioactive compounds and nutraceuticals. Regular consumption of fruit and vegetables helps prevent the onset and progression of many non-communicable diseases. The Mediterranean diet envisages consumption of healthy vegetables and fruit on a daily basis for maximum health benefits. Traditional use envisages vegetable-based and fruit-based diets, and many studies scientifically proved the beneficial effects of Mediterranean vegetables and fruits. Rich in bioactive phytochemicals, citrus, cucumbers and grapes have antioxidant, anti-inflammatory, antimicrobial, cardioprotective, anti-ageing and anti-cancer properties. Studies indicate that intake of citrus, cucumbers and grapes reduces hypertension, hyperlipidemia, skin problems and infections and improves the health of the cardiovascular and nervous systems. These beneficial effects are mediated by several bioactive molecules present in Mediterranean diet vegetables and fruits, such as citrus, cucumbers and grapes. Indeed, they contains flavones, isoflavones, tannins, polyphenols and many beneficial natural molecules. This review focuses on the bioactive ingredients in citrus fruit, cucumbers and grapes, all components of the Mediterranean diet, and their health effects. A deep understanding of Mediterranean diet’s components, as well as clinical trials to test natural molecules beneficial effects, will permit to further explore the therapeutic potential of the Mediterranean diet in several pathological conditions.
description: Journal of Preventive Medicine and Hygiene, Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods
Foods of the Mediterranean diet: Garlic and Mediterranean legumes
Creators: name: Medori, Maria Chiara
name: Naureen, Zakira
name: Bonetti, Gabriele
name: Velluti, Valeria
name: Aquilanti, Barbara
name: Matera, Giuseppina
name: Iaconelli, Amerigo
name: Bertelli, Matteo
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2022

description: The Mediterranean diet is a dietary regime derived from the one followed by the ancient civilizations of the Mediterranean region. It is characterized by many healthy constituents, among which are cereals, legumes, fruits, vegetables, olives, and white meat. Many studies suggest that this dietary regime is the key to obtaining a healthy and long life, like that of the Mediterranean peoples. Despite its popularity among health professionals, this diet is still confined to a certain geographical area of the world. Due to globalization and the modern busy lifestyle, this cultural diet is losing ground even in its home region, with more and more people embracing the so-called Western diet. An awareness of health benefits of the individual components of the Mediterranean diet will therefore draw attention from all over the world to this healthy and affordable dietary pattern, which can not only improve the overall health, but also reduce the risk of developing chronic and infectious diseases. In this regard, garlic and Mediterranean legumes present a huge repertoire of phytochemicals having both nutritive and nutraceutical properties, which therefore should be included in our daily dietary routines in moderate proportions. This narrative review aims at summarizing the principal components and health benefits of the Mediterranean diet, in particular of garlic and legumes
description: Journal of Preventive Medicine and Hygiene, Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods
title: [Arbeitsberichte] Bestandsicherung der Kirnburg. Ein Zwischenbericht
Creators: name: Hillenbrand, Peter
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 9, Nr. 1 (1980), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Foods of the Mediterranean diet: tomato, olives, chili pepper, wheat flour and wheat germ
Creators: name: Zakira Naureen, Zakira
name: DHULI, KRISTJANA
name: Donato, Kevin
name: Aquilanti, Barbara
name: Velluti, Valeria
name: Matera, Giuseppina
name: Iaconelli, Amerigo
name: Bertelli, Matteo
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2022

description: Mediterranean people, which follows a diet rich in minimally-processed plant-based foods, are believed to live longer and healthier lives than many other populations in the Western world. Epidemiological and clinical data suggest that the Mediterranean diet has beneficial effects for several chronic diseases, such as cardiovascular diseases, obesity, cancer and diabetes. Although the mechanisms of action of the Mediterranean diet are not completely clear, the synergistic effects of a number of its components and their bioactive phytochemicals exert antioxidant, anti-inflammatory, anti-microbial and anti-cancer effects. The Mediterranean diet includes daily consumption of whole cereals, fruit, vegetables and legumes in moderate proportions, weekly consumption of white meat in low to moderate proportions and occasionally sweets and chocolates in small amounts. Since olive oil is the main lipids source, it has special significance for health. Healthy fruit and vegetables, rich in phytochemicals, are a major proportion of this diet and contribute to the overall nutritional value and bioactivity of its components. Here we review the nutritional and health benefits of wheat germ, tomatoes, olives and chili pepper, items at the base of Mediterranean diet food pyramid that provides beneficial molecules, such as polyphenols, vitamins and flavonoids, and exert anti-inflammatory, anti-microbial and anti-oxidative actions.
description: Journal of Preventive Medicine and Hygiene, Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods
Extension of derivations, and Connes-amenability of the enveloping dual Banach algebra
Creators: name: Choi, Yemon
name: Samei, Ebrahim
name: Stokke, Ross
Publisher: name: arXiv
Year: 2013
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: If $D:A \to X$ is a derivation from a Banach algebra to a contractive, Banach $A$-bimodule, then one can equip $X^{**}$ with an $A^{**}$-bimodule structure, such that the second transpose $D^{**}: A^{**} \to X^{**}$ is again a derivation. We prove an analogous extension result, where $A^{**}$ is replaced by $\F(A)$, the \emph{enveloping dual Banach algebra} of $A$, and $X^{**}$ by an appropriate kind of universal, enveloping, normal dual bimodule of $X$. Using this, we obtain some new characterizations of Connes-amenability of $\F(A)$. In particular we show that $\F(A)$ is Connes-amenable if and only if $A$ admits a so-called WAP-virtual diagonal. We show that when $A=L^1(G)$, existence of a WAP-virtual diagonal is equivalent to the existence of a virtual diagonal in the usual sense. Our approach does not involve invariant means for $G$.
description: v2: AMS-LaTeX, 11pt, 40 pages. Various minor improvements and corrections, including changes to notation and additional references; also new material in Sections 5 and 6. Incorporates referee's revisions. To appear in Mathematica Scandinavica
Funding the Search for Extraterrestrial Intelligence with a Lottery Bond
Creators: name: Haqq-Misra, Jacob
Publisher: name: arXiv
Year: 2013
Subjects: subject: Popular Physics (physics.pop-ph)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: I propose the establishment of a SETI Lottery Bond to provide a continued source of funding for the search for extraterrestrial intelligence (SETI). The SETI Lottery Bond is a fixed rate perpetual bond with a lottery at maturity, where maturity occurs only upon discovery and confirmation of extraterrestrial intelligent life. Investors in the SETI Lottery Bond purchase shares that yield a fixed rate of interest that continues indefinitely until SETI succeeds---at which point a random subset of shares will be awarded a prize from a lottery pool. SETI Lottery Bond shares also are transferable, so that investors can benefact their shares to kin or trade them in secondary markets. The total capital raised this way will provide a fund to be managed by a financial institution, with annual payments from this fund to support SETI research, pay investor interest, and contribute to the lottery fund. Such a plan could generate several to tens of millions of dollars for SETI research each year, which would help to revitalize and expand facilities such as the Allen Telescope Array. The SETI Lottery Bond is a savings product that only can be offered by a financial institution with authorization to engage in banking and gaming activities. I therefore suggest that one or more banks offer a lottery-linked savings product in support of SETI research, with the added benefit of promoting personal savings and intergenerational wealth building among individuals.
description: Published in Space Policy
Independent events and their complements. Part II
Creators: name: Mizuno, Gabriel Perez
name: Crispim, Carolina Martins
name: Pizzinga, Adrian
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: In a previous classroom note (Crispim et al., 2021), we addressed the proving (and the teaching) of a former and famous probability fact: if n random events are independent, then changing one, some, or all of them by the corresponding complements ends up again with independent events. Now, we explore the consequences. The first, for example, is the extension to when the number of events are infinite – which, indeed and perhaps surprisingly, stands as a corollary of the finite case. Also, and beyond covering only two events, we deal with the logical and intuitive consistency between independence and conditional probability. The theoretical content concludes with a proof that two seemingly different definitions of independent events found in the literature actually compare. Then, we finish the paper by discussing some classroom possibilities.
From Achille Bertelli onward: more than 100 years of research and production of dietary supplements based on natural molecules typical of the Mediterranean diet
Creators: name: Medeghini, Valentina
name: Donato, Kevin
name: Gaudenzi, Silvia
name: Bonetti, Gabriele
name: Bertelli, Matteo
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2022

description: Achille Bertelli was an aeronautics pioneer and an innovative entrepreneur of the pharmaceutical industry. After graduating in Chemistry in Italy, he moved to the United States of America where he opened a chemical-pharmaceutical laboratory in San Francisco in 1879, and later moved back to Italy where he opened a chemical and pharmaceutical industry in Milan (1886). The “A. Bertelli” pharmaceutical company developed the famous cough pills “Catramina Bertelli”, as well as new cosmetics and perfumes. Apart from his chemical experience, Achille Bertelli was a passionate aeronautics expert. He wrote many essays on this topic and devoted himself to aeronautical experiments by designing theapparatus “Autovol”, “Aerocurvo”, “Autovol no. 2”, “Autovolno. 3", which are considered the prototypes of the helicopter. Achille Bertelli was also the president of the Electric Company of Salò, which installed an electrical system that served the lighting in many cities on Lake Garda (Italy). Finally, Achille Bertelli also participated in the Italian revival after the First World War, especially by supporting the agricultural revival. Throughout his life, Achille Bertelli teamed with several famous people from all over Italy, such as Gabriele D’Annunzio, Cesare Lombroso and Cordero di Montezemolo. Today, Achille Bertelli’s interest for natural molecules, his ideas, and his entrepreneurial approach are carried forward by his descendant, Matteo Bertelli.
description: Journal of Preventive Medicine and Hygiene, Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods
Einstein-Podolsky-Rosen-steering using quantum correlations in non-Gaussian entangled states
Creators: name: Chowdhury, Priyanka
name: Pramanik, Tanumoy
name: Majumdar, A. S.
name: Agarwal, G. S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In view of the increasing importance of non-Gaussian entangled states in quantum information protocols like teleportation and violations of Bell inequalities, the steering of continuous variable non-Gaussian entangled states is investigated. The EPR steering for Gaussian states may be demonstrated through the violation of the Reid inequality involving products of the inferred variances of non-commuting observables. However, for arbitrary states the Reid inequality is not always necessary because of the higher order correlations in such states. One then needs to use the entropic steering inequality. We examine several classes of currently important non-Gaussian entangled states, such as the two-dimensional harmonic oscillator, the photon subtracted two mode squeezed vacuum, and the NOON state, in order to demonstrate the steering property of such states. A comparative study of the violation of the Bell-inequality for these states shows that the entanglement present is more easily revealed through steering compared to Bell-violation for several such states.
description: 11 pages, 4 figures
Gas-to-nanotextile: high-performance materials from floating 1D nanoparticles
Creators: name: Gómez-Palos, Isabel
name: Vazquez-Pufleau, Miguel
name: Schäufele, Richard S
name: Mikhalchan, Anastasiia
name: Pendashteh, Afshin
name: Ridruejo, Álvaro
name: Vilatela, Juan J.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Suspended in the gas phase, 1D inorganic nanoparticles (nanotubes and nanowires) grow to hundreds of microns in a second and can be thus directly assembled into freestanding network materials. The corresponding process continuously transforms gas precursors into aerosols into aerogels into macroscopic nanotextiles. By enabling the assembly of very high aspect ratio nanoparticles, this processing route has translated into high-performance structural materials, transparent conductors and battery anodes, amongst other embodiments. This paper reviews progress in the application of such manufacturing process to nanotubes and nanowires. It analyses 1D nanoparticle growth through floating catalyst chemical vapour deposition (FCCVD), in terms of reaction selectivity, scalability and its inherently ultra-fast growth rates (107-108 atoms per second) up to 1000 times faster than for substrate CVD. We summarise emerging descriptions of the formation of aerogels through percolation theory and multi-scale models for the collision and aggregation of 1D nanoparticles. The paper shows that macroscopic ensembles of 1D nanoparticles resemble textiles in their porous network structure, high flexibility and damage-tolerance. Their bulk properties depend strongly on inter-particle properties and are dominated by alignment and volume fraction. Selected examples of nanotextiles that surpass granular and monolithic materials include structural fibres with polymer-like toughness, transparent conductors, and slurry-free composite electrodes for energy storage.
description: 36 pages, 25 figures
title: Inhalt
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 11, Nr. 1 (1982), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Building patterns by traveling vortices and dipoles in periodic dissipative media
Creators: name: Besse, Valentin
name: Leblond, Herve
name: Mihalache, Dumitru
name: Malomed, Boris A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We analyze pattern-formation scenarios in the two-dimensional (2D) complex Ginzburg-Landau (CGL) equation with the cubic-quintic (CQ) nonlinearity and a cellular potential. The equation models laser cavities with built-in gratings, which are used to stabilize 2D patterns. The pattern-building process is initiated by kicking a localized compound mode, in the form of a dipole, quadrupole, or vortex which is composed of four local peaks. The hopping motion of the kicked mode through the cellular structure leads to the generation of various extended patterns pinned by the structure. In the ring-shaped system, the persisting freely moving dipole hits the stationary pattern from the opposite side, giving rise to several dynamical regimes, with the pinned multi-soliton chain playing the role of the Newton's cradle (NC).
title: [Nachruf] Gerhard Krämer
Creators: name: Anstett, Peter
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 11, Nr. 1 (1982), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Complexity and entanglement in non-local computation and holography
Creators: name: May, Alex
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Does gravity constrain computation? We study this question using the AdS/CFT correspondence, where computation in the presence of gravity can be related to non-gravitational physics in the boundary theory. In AdS/CFT, computations which happen locally in the bulk are implemented in a particular non-local form in the boundary, which in general requires distributed entanglement. In more detail, we recall that for a large class of bulk subregions the area of a surface called the ridge is equal to the mutual information available in the boundary to perform the computation non-locally. We then argue the complexity of the local operation controls the amount of entanglement needed to implement it non-locally, and in particular complexity and entanglement cost are related by a polynomial. If this relationship holds, gravity constrains the complexity of operations within these regions to be polynomial in the area of the ridge.
description: v5 adds doi's to bibliography
Gene variants in Eating Disorders. Focus on Anorexia Nervosa Bulimia Nervosa and Binge-eating Disorder
Creators: name: Donato, Kevin
name: Ceccarini, Maria Rachele
name: Dhuli, Kristjana
name: Bonetti, Gabriele
name: Medori, Maria Chiara
name: Marceddu, Giuseppe
name: Precone, Vincenza
name: Xhufi, Suela
name: Bushati, Marsida
name: Bozo, Dhurata
name: Beccari, Tommaso
name: Bertelli, Matteo
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2022

description: Eating disorders such as anorexia nervosa, bulimia nervosa and binge-eating disorder, have a deep social impact, concluding with death in cases of severe disease. Eating disorders affect up to 5% of the population in the industrialized countries, but probably the phenomenon is under-detection and under-diagnosis. Eating disorders are multifactorial disorders, resulting from the interaction between environmental triggers, psychological factors, but there is also a strong genetic component. In fact, genetic factors predispose for approximately 33-84% to anorexia nervosa, 28-83% to bulimia nervosa, and 41-57% to binge eating disorder. Twins and family studies have provided an unassailable proof on the heritability of these disorders. Other types of genetic studies, including genome-wide association studies, whole genome sequencing and linkage analysis, allowed to identify the genes and their variants associated with eating disorders and moreover global collaborative efforts have led to delineate the etiology of these disorders. Next Generation Sequencing technologies can be considered as an ideal diagnostic approach to identify not only the common variants, such as single nucleotide polymorphism, but also rare variants. Here we summarize the present knowledge on the molecular etiology and genetic determinants of eating disorders including serotonergic genes, dopaminergic genes, opioid genes, appetite regulation genes, endocannabinoid genes and vitamin D3.
description: Journal of Preventive Medicine and Hygiene, Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods
Dynamical versus diffraction spectrum for structures with finite local complexity
Creators: name: Baake, Michael
name: Lenz, Daniel
name: van Enter, Aernout
Publisher: name: arXiv
Year: 2013
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37B10, 37B50, 43A25, 52C23

description: It is well-known that the dynamical spectrum of an ergodic measure dynamical system is related to the diffraction measure of a typical element of the system. This situation includes ergodic subshifts from symbolic dynamics as well as ergodic Delone dynamical systems, both via suitable embeddings. The connection is rather well understood when the spectrum is pure point, where the two spectral notions are essentially equivalent. In general, however, the dynamical spectrum is richer. Here, we consider (uniquely) ergodic systems of finite local complexity and establish the equivalence of the dynamical spectrum with a collection of diffraction spectra of the system and certain factors. This equivalence gives access to the dynamical spectrum via these diffraction spectra. It is particularly useful as the diffraction spectra are often simpler to determine and, in many cases, only very few of them need to be calculated.
description: 27 pages; some minor revisions and improvements
title: Quellennachweis für die Abbildungen
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 11, Nr. 1 (1982), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Oligonucleotide-recognizing topoisomerase inhibitors (OTIs): Precision gene editors for neurodegenerative diseases?
Creators: name: Bax, Ben D
name: Sutormin, Dmitry
name: McDonald, Neil Q
name: Burley, Glenn A
name: Shelkovnikova, Tatyana
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: Biochemistry & Proteomics
Structural Biology & Biophysics
Signalling & Oncogenes

description: Topoisomerases are essential enzymes that recognize and modify the topology of DNA to allow DNA replication and transcription to take place. Topoisomerases are divided into type I topoisomerases, that cleave one DNA strand to modify DNA topology, and type II, that cleave both DNA strands. Topoisomerases normally rapidly religate cleaved-DNA once the topology has been modified. Topoisomerases do not recognize specific DNA sequences, but actively cleave positively supercoiled DNA ahead of transcription bubbles or replication forks, and negative supercoils (or precatenanes) behind, thus allowing the unwinding of the DNA-helix to proceed (during both transcription and replication). Drugs that stabilize DNA-cleavage complexes with topoisomerases produce cytotoxic DNA damage and kill fast-dividing cells; they are widely used in cancer chemotherapy. Oligonucleotide-recognizing topoisomerase inhibitors (OTIs) have given drugs that stabilize DNA-cleavage complexes specificity by linking them to either: (i) DNA duplex recognizing triplex forming oligonucleotide (TFO-OTIs) or DNA duplex recognizing pyrrole-imidazole-polyamides (PIP-OTIs) (ii) or by conventional Watson-Crick base pairing (WC-OTIs). This converts compounds from indiscriminate DNA-damaging drugs to highly specific targeted DNA-cleaving OTIs. Herein we propose simple strategies to enable DNA-duplex strand invasion of WC-OTIs giving strand-invading SI-OTIs. This will make SI-OTIs similar to the guide RNAs of CRISPR/Cas9 nuclease bacterial immune systems. However, an important difference between OTIs and CRISPR/Cas9, is that OTIs do not require the introduction of foreign proteins into cells. Recent successful oligonucleotide therapeutics for neurodegenerative diseases suggest that OTIs can be developed to be highly specific gene editing agents for DNA lesions that cause neurodegenerative diseases.
title: [Nachruf] Werner von Matthey
Creators: name: Krins, Hubert
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 11, Nr. 2 (1982), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
GPT-3 Abstract Classification for Scientometrics
Creators: name: Büttner, Jochen
Publisher: name: Zenodo
Year: 2023
Subjects: GPT-3, ANZSRC, Scientometrics

description: This working paper shows how to fine-tune and use a GPT-3 model to assign publications, based on their abstracts, to a commonly used scientific classification scheme, the Australian and New Zealand Standard Research Classification system (ANZSRC). The work was carried out in the context of the project "ModelSEN: Socioepistemic Networks: Modelling Historical Knowledge Processes" (BMBF Grant No. 01 UG2131). The full Jupyter book, which also links to the code base, can be accessed at https://modelsen.mpiwg-berlin.mpg.de/compendium.
title: Veröffentlichungen des Landesdenkmalamtes
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 11, Nr. 2 (1982), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Geometric multigrid for an implicit-time immersed boundary method
Creators: name: Guy, Robert D.
name: Philip, Bobby
name: Griffith, Boyce E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65F08, 65M55, 76M20

description: The immersed boundary (IB) method is an approach to fluid-structure interaction that uses Lagrangian variables to describe the structure and Eulerian variables to describe the fluid. Explicit time stepping schemes for the IB method require solvers only for Eulerian equations, for which fast Cartesian grid solution methods are available. Such methods are relatively straightforward to develop and are widely used in practice but often require very small time steps to maintain stability. Implicit-time IB methods permit the stable use of large time steps, but efficient implementations of such methods require significantly more complex solvers that effectively treat both Lagrangian and Eulerian variables simultaneously. Several different approaches to solving the coupled Lagrangian-Eulerian equations have been proposed, but a complete understanding of this problem is still emerging. This paper presents a geometric multigrid method for an implicit-time discretization of the IB equations. This multigrid scheme uses a generalization of box relaxation that is shown to handle problems in which the physical stiffness of the structure is very large. Numerical examples are provided to illustrate the effectiveness and efficiency of the algorithms described herein. These tests show that using multigrid as a preconditioner for a Krylov method yields improvements in both robustness and efficiency as compared to using multigrid as a solver. They also demonstrate that with a time step 100--1000 times larger than that permitted by an explicit IB method, the multigrid-preconditioned implicit IB method is approximately 50--200 times more efficient than the explicit method.
Microtubule organization and cell geometry
Creators: name: Foteinopoulos, Panayiotis
name: Mulder, Bela M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Biomolecules (q-bio.BM)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Biological sciences

description: We present a systematic study of the influence of cell geometry on the orientational distribution of microtubules (MTs) nucleated from a single microtubule organizing center (MTOC). For simplicity we consider an elliptical cell geometry, a setting appropriate to a generic non-spherical animal cell. Within this context we introduce four models of increasing complexity, in each case introducing additional mechanisms that govern the interaction of the MTs with the cell boundary. In order, we consider the cases: MTs that can bind to the boundary with a fixed mean residence time (M0), force-producing MTs that can slide on the boundary towards the cell poles (MS), MTs that interact with a generic polarity factor that is transported and deposited at the boundary, and which in turn stabilizes the MTs at the boundary (MP), and a final model in which both sliding and stabilization by polarity factors is taken into account (MSP). In the baseline model (M0), the exponential length distribution of MTs causes most of the interactions at the cell boundary to occur along the shorter transverse direction in the cell, leading to transverse biaxial order. MT sliding (MS) is able to reorient the main axis of this biaxial order along the longitudinal axis. The polarization mechanism introduced in MP and MSP overrules the geometric bias towards bipolar order observed in M0 and MS, and allows the establishment of unipolar order either along the short- (MP) or the long cell axis (MSP). The behavior of the latter two models can be qualitatively reproduced by a very simple toy model with discrete MT orientations.
description: 38 pages, 13 figures
Proton structure and tensor gluons
Creators: name: Savvidy, George
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider a possibility that inside the proton and, more generally, inside the hadrons there are additional partons - tensor-gluons, which can carry a part of the proton momentum. The tensor-gluons have zero electric charge, like gluons, but have a larger spin. Inside the proton a nonzero density of the tensor-gluons can be generated by the emission of tensor-gluons by gluons. The last mechanism is typical for non-Abelian tensor gauge theories, in which there exists a gluon-tensor-tensor vertex of order g. Therefore the number of gluons changes not only because a quark may radiate a gluon or because a gluon may split into a quark-antiquark pair or into two gluons, but also because a gluon can split into two tensor-gluons. The process of gluon splitting suggests that part of the proton momentum which was carried by neutral partons is shared between vector and tensor gluons. We derive evolution equations for the parton distribution functions which take into account these new processes. The momentum sum rule allows to find the tensor-gluons contribution to the Callan-Simanzik beta function and to calculate the corresponding anomalous dimensions. This contribution changes the behavior of the structure functions, and the logarithmic correction to the Bjorken scaling becomes more mild. This also influences the unification scale at which the coupling constants of the Standard Model merge, shifting its value to lower energies of order of 40 TeV.
description: 20 pages, LaTex, minor corrections, version accepted for publication
title: Mitteilungen ; Quellennachweis für die Abbildungen
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 11, Nr. 3 (1982), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Multipliers of embedded discs
Creators: name: Davidson, Kenneth R.
name: Hartz, Michael
name: Shalit, Orr
Publisher: name: arXiv
Year: 2013
Subjects: subject: Operator Algebras (math.OA)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 47L30, 47A13, 46E22

description: We consider a number of examples of multiplier algebras on Hilbert spaces associated to discs embedded into a complex ball in order to examine the isomorphism problem for multiplier algebras on complete Nevanlinna-Pick reproducing kernel Hilbert spaces. In particular, we exhibit uncountably many discs in the ball of $\ell^2$ which are multiplier biholomorphic but have non-isomorphic multiplier algebras. We also show that there are closed discs in the ball of $\ell^2$ which are varieties, and examine their multiplier algebras. In finite balls, we provide a counterpoint to a result of Alpay, Putinar and Vinnikov by providing a proper rational biholomorphism of the disc onto a variety $V$ in $\mathbb B_2$ such that the multiplier algebra is not all of $H^\infty(V)$. We also show that the transversality property, which is one of their hypotheses, is a consequence of the smoothness that they require.
description: 34 pages; the earlier version relied on a result of Davidson and Pitts that the fibre of the maximal ideal space of the multiplier algebra over a point in the open ball consists only of point evaluation. This result fails for $d = \infty$, and has necessitated some changes; to appear in Complex Analysis and Operator Theory
Gelfand spectra in Grothendieck toposes using geometric mathematics
Creators: name: Spitters, Bas
name: Vickers, Steven
name: Wolters, Sander
Publisher: name: arXiv
Year: 2013
Subjects: subject: Category Theory (math.CT)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: In the (covariant) topos approach to quantum theory by Heunen, Landsman and Spitters, one associates to each unital C*-algebra, A, a topos T(A) of sheaves on a locale and a commutative C*-algebra, a, within that topos. The Gelfand spectrum of a is a locale S in this topos, which is equivalent to a bundle over the base locale. We further develop this external presentation of the locale S, by noting that the construction of the Gelfand spectrum in a general topos can be described using geometric logic. As a consequence, the spectrum, seen as a bundle, is computed fibrewise. As a by-product of the geometricity of Gelfand spectra, we find an explicit external description of the spectrum whenever the topos is a functor category. As an intermediate result we show that locally perfect maps compose, so that the externalization of a locally compact locale in a topos of sheaves over a locally compact locale is locally compact, too.
description: In Proceedings QPL 2012, arXiv:1407.8427
title: Neurosarcoidosis
Creators: name: Meglic, Jakob
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Neuroradiology
subject: Neuroradiology brain
subject: MR
subject: Clinical Cases

description: Clinical History: A 44-year-old man with chronic anterior uveitis had his first epileptic seizure. He displayed severe psychomotor retardation, moderate apraxia of the right hand, and no other neurological symptoms. MRI and skin lesion biopsy confirmed the diagnosis. Methotrexate treatment led to marked improvement seen in a follow-up MRI after 3 months.

description: 44 years, male
title: Dienststellen des Landesdenkmalamtes
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 14, Nr. 1 (1985), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Synthesizing Attack-Aware Control and Active Sensing Strategies under Reactive Sensor Attacks
Creators: name: Udupa, Sumukha
name: Kulkarni, Abhishek N.
name: Han, Shuo
name: Leslie, Nandi O.
name: Kamhoua, Charles A.
name: Fu, Jie
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optimization and Control (math.OC)
subject: Computer Science and Game Theory (cs.GT)
subject: Systems and Control (eess.SY)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: We consider the probabilistic planning problem for a defender (P1) who can jointly query the sensors and take control actions to reach a set of goal states while being aware of possible sensor attacks by an adversary (P2) who has perfect observations. To synthesize a provably-correct, attack-aware joint control and active sensing strategy for P1, we construct a stochastic game on graph with augmented states that include the actual game state (known only to the attacker), the belief of the defender about the game state (constructed by the attacker based on his knowledge of defender's observations). We present an algorithm to compute a belief-based, randomized strategy for P1 to ensure satisfying the reachability objective with probability one, under the worst-case sensor attack carried out by an informed P2. We prove the correctness of the algorithm and illustrate using an example.
description: 7 pages, 3 figure, 1 table, 1 algorithm
Leptogenesis and Dark Matter-Nucleon Scattering Cross Section in the SE6SSM
Creators: name: Nevzorov, Roman
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The E6 inspired extension of the minimal supersymmetric (SUSY) standard model (MSSM) with an extra U(1)_N gauge symmetry, under which right-handed neutrinos have zero charge, involves exotic matter beyond the MSSM to ensure anomaly cancellation. We consider the variant of this extension (SE6SSM) in which the cold dark matter is composed of the lightest neutral exotic fermion and gravitino. The observed baryon asymmetry can be induced in this case via the decays of the lightest right-handed neutrino/sneutrino into exotic states even for relatively low reheating temperatures T_R < 10^{6-7} GeV. We argue that there are some regions of the SE6SSM parameter space, which are safe from all current constraints, and discuss the implications of this model for collider phenomenology.
description: 30 pages, 3 figures
title: Veröffentlichungen des Landesdenkmalamtes
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2014

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 14, Nr. 4 (1985), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4