cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
DIM5/KMT1 controls fungal insect pathogenicity and genome stability by methylation of histone H3K4, H3K9 and H3K36
Creators: name: Ren, Kang
name: Mou, Ya-Ni
name: Tong, Sen-Miao
name: Ying, Sheng-Hua
name: Feng, Ming-Guang
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Mono-, di- and tri-methylation of histone H3 Lys 9, Lys 4, and Lys 36 (H3K_me1/me2/me3) required for mediation of DNA-based cellular events in eukaryotes usually rely upon the activities of histone lysine methyltransferases (KMTs) classified to the KMT1, KMT2, and KMT3 families, respectively. Here, an H3K9-specific DIM5/KMT1 orthologue, which lacks a C-terminal post-SET domain and localizes mainly in nucleus, is reported to have both conserved and noncanonical roles in methylating the H3 core lysines in Beauveria bassiana, an insect-pathogenic fungus serving as a main source of wide-spectrum fungal insecticides. Disruption of dim5 led to abolishment of H3K9me3 and marked attenuation of H3K4me1/me2, H3K9me1/me2 and H3K36me2. Consequently, the Δdim5 mutant lost the whole insect pathogenicity through normal cuticle infection, and was compromised severely in virulence through cuticle-bypassing infection (hemocoel injection) and also in a series of cellular events critical for the fungal virulence and lifecycle in vivo and in vitro, including reduced hyphal growth, blocked conidiation, impeded proliferation in vivo, altered carbohydrate epitopes, disturbed cell cycle, reduced biosynthesis and secretion of cuticle-degrading enzymes, and increased sensitivities to various stresses. Among 1,201 dysregulated genes (up/down ratio: 712:489) associated with those phenotypic changes, 92 (up/down ratio: 59:33) encode transcription factors and proteins or enzymes involved in posttranslational modifications, implying that the DIM5-methylated H3 core lysines could act as preferential marks of those transcription-active genes crucial for global gene regulation. These findings uncover a novel scenario of DIM5 and its indispensability for insect-pathogenic lifestyle and genome stability of B. bassiana.
Text
Creators: name: Sillman, Brady
Publisher: name: figshare
Year: 2017
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Pathology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Manuscript text
Politics and policy: an analysis of the policy environment and motivating factors behind the English language policy in Rwanda
Creators: name: Nogic, Claire
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This thesis aims to examine the motivating factors behind the English Language Policy in Rwanda. This policy was implemented in late 2008 and represents a shift in the linguistic landscape of Rwanda from an era of trilingualism to bilingualism. Subsequently, French is no longer the medium of instruction in education or the language of choice in business and government. This policy reflects the various policy networks and elite in Rwanda and is anchored in the policy environment of the state. -- Chapter 1 provides some initial insights into the background of Rwanda's history and the English Language Policy. It presents a conceptual framework for this research by examining three theories, namely Elite Theory, Policy Networks and the policy environment which are highly applicable to the Rwandan context. -- Chapter 2 examines the history of Rwanda from pre-colonial times to present day. This confers an understanding of the policy environment and particularly the changing elite, ideologies and policies of the state. -- Chapter 3 explores public policy with an emphasis on the public motivations behind the English Language Policy in Rwanda. It analyses the motivations of globalisation and geostrategic pragmatism, the reasons given by policy-makers for the design of this policy. -- Chapter 4 addresses the hidden motivations behind this policy, namely the anti-French sentiment in the Rwandan state due to the explicit involvement of French actors in the years leading up to and during the genocide of 1994. -- Chapter 5 asserts that the English Language Policy was written as a result of both the public and hidden motivations of elites in positions of power in Rwanda. Furthermore, it formulates recommendations for further research.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 1326
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1326, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1326, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Investigating the "kink" plot as a signal of the onset of deconfinement
Creators: name: Naskręt, Michał
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: One of the physics goals of the NA61/SHINE collaboration at the CERN Super Proton Synchrotron is to study the phase diagram of hadronic matter. To this end, a series of heavy ion collision measurements are performed. It is believed that above a certain collision energy and system size a phase transition between hadronic matter and quark-gluon plasma occurs. A number of observables has been developed to determine which of the phases was created at the early stage of the collision. This report discusses the dependence of the ratio of the mean number of produced pions to the mean number of wounded nucleons on the Fermi energy measure. For comparison with other measurements this is often presented in the form of the the "kink" plot. This plot is presented enriched with preliminary results for Ar+Sc central collisions at 13A, 19A, 30A, 40A, 75A and 150A GeV/c beam momentum. The results are finally compared to data from other experiments.
Roborovski hamster (Phodopus roborovskii) strain SH101 as a systemic infection model of SARS-CoV-2
Creators: name: Zhai, Chongkai
name: Wang, Mingda
name: Chung, Hea-Jong
name: Hassan, Md. Mehedi
name: Lee, Seungkoo
name: Kim, Hyeon-Jin
name: Hong, Seong-Tshool
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Severe acute respiratory syndrome CoV-2 (SARS-CoV-2) is currently causing a worldwide threat with its unusually high transmission rates and rapid evolution into diverse strains. Unlike typical respiratory viruses, SARS-CoV-2 frequently causes systemic infection by breaking the boundaries of the respiratory systems. The development of animal models recapitulating the clinical manifestations of COVID-19 is of utmost importance not only for the development of vaccines and antivirals but also for understanding the pathogenesis. However, there has not been developed an animal model for systemic infection of SARS-CoV-2 representing most aspects of the clinical manifestations of COVID-19 with systemic symptoms. Here we report that a Roborovski hamster strain SH101, a laboratory inbred hamster strain of P. roborovskii, displayed most symptoms of systemic infection upon SARS-CoV-2 infection as in the case of the human counterpart, unlike current COVID-19 animal models. Roborovski hamster strain SH101 post-infection of SARS-CoV-2 represented most clinical symptoms of COVID-19 such as snuffling, labored breathing, dyspnea, cough, hunched posture, progressive weight loss, ruffled fur, and high fever following shaking chills. Histological examinations also revealed initial right-predominated pneumonia as well as slight organ damages in the brain and liver, manifesting systemic COVID-19 cases. Considering the merit of a small animal as well as its clinical manifestations of SARS-CoV-2 infection in human, this hamster model seems to provide an ideal tool to investigate COVID-19.
Investigação em educação musical: perspectivas para o seu desenvolvimento em Portugal
Creators: name: Boal-Palheiros, Graça
Publisher: name: Revista Música, Psicologia e Educação
Year: 2017

description: As profundas transformações ocorridas na sociedade portuguesa, em geral, e na educação e na música, em particular, durante as duas últimas décadas, têm suscitado inúmeros debates nos meios educativos e nos órgãos de comunicação social. A expansão do ensino da música parece ter estimulado o desenvolvimento de uma maior consciência do papel da educação musical, bem como da necessidade de investigação nesta área. Nesta apresentação são abordadas diversas questões relativas à investigação em educação musical em geral e, em particular, no nosso país. São salientadas a necessidade e a importância da investigação no contexto educativo português, referindo-se o desenvolvimento recente da investigação em educação musical em Portugal. Algumas metodologias de investigação são apresentadas sumariamente e são também sugeridos temas e áreas de investigação considerados pertinentes.
description: Revista Música, Psicologia e Educação, n. 1 (1999): Revista Música, Psicologia e Educação
Additional file 2 of Patterns of physical activity over time in older patients rehabilitating after hip fracture surgery: a preliminary observational study
Creators: name: van Dartel, Dieuwke
name: Wang, Ying
name: Hegeman, Johannes H.
name: Vermeer, Marloes
name: Vollenbroek-Hutten, Miriam M. R.
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health

description: Additional file 2. Ratings of all raters for each patient and for each aspect of physical activity.
Phase reduction approach to synchronization of nonlinear oscillators
Creators: name: Nakao, Hiroya
Publisher: name: arXiv
Year: 2017
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: Systems of dynamical elements exhibiting spontaneous rhythms are found in various fields of science and engineering, including physics, chemistry, biology, physiology, and mechanical and electrical engineering. Such dynamical elements are often modeled as nonlinear limit-cycle oscillators. In this article, we briefly review phase reduction theory, which is a simple and powerful method for analyzing the synchronization properties of limit-cycle oscillators exhibiting rhythmic dynamics. Through phase reduction theory, we can systematically simplify the nonlinear multi-dimensional differential equations describing a limit-cycle oscillator to a one-dimensional phase equation, which is much easier to analyze. Classical applications of this theory, i.e., the phase locking of an oscillator to a periodic external forcing and the mutual synchronization of interacting oscillators, are explained. Further, more recent applications of this theory to the synchronization of non-interacting oscillators induced by common noise and the dynamics of coupled oscillators on complex networks are discussed. We also comment on some recent advances in phase reduction theory for noise-driven oscillators and rhythmic spatiotemporal patterns.
description: Brief review of the phase reduction theory for limit-cycle oscillators, 53 pages, 11 figures
Ce2Pd21Si6 vs Ce3Pd20Si6: ВЛИЯНИЕ ЗАМЕЩЕНИЯ Ce/Pd НА ФИЗИЧЕСКИЕ СВОЙСТВА
Creators: name: Семено А.В.
name: Анисимов М.А.
name: Богач А.В.
name: Демишев С.В.
name: Щелкачев Н.М.
name: Краснорусский В.Н.
name: Грибанов А.В.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: В настоящей работе синтезированы поликристаллические интерметаллические соединения Ce3-xPd20+xSi6 (x = 0; 0.5; 1), а также аналоги на основе La La3-xPd20+xSi6 (x = 0; 1).
Additional file 3 of Patterns of physical activity over time in older patients rehabilitating after hip fracture surgery: a preliminary observational study
Creators: name: van Dartel, Dieuwke
name: Wang, Ying
name: Hegeman, Johannes H.
name: Vermeer, Marloes
name: Vollenbroek-Hutten, Miriam M. R.
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health

description: Additional file 3. Patient characteristics for each pattern of physical activity of all three aspects of physical activity.
COLLECTIVE NATURE OF LOW-TEMPERATURE CONDUCTION, PHOTOCONDUCTION AND CHARGE DENSITY WAVE PINING IN ORTHORHOMBIC TaS3
Creators: name: Minakova V. E .
name: Zaitsev-Zotov S., V.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: This work summarizes the results of a series of works devoted to the study of low-temperature conduction and photoconduction of the Peierls conductor o-TaS3.
COLLECTIVE MODES IN DIRTY 2D SUPERCONDUCTORS
Creators: name: Бурмистров И. С.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: We develop the theory of quantum fluctuations within such multifractally-enhanced superconducting states in thin films.
Simulating Molecular Spectroscopy with Circuit Quantum Electrodynamics
Creators: name: Hu, Ling
name: Ma, YueChi
name: Xu, Y.
name: Wang, W.
name: Ma, Y.
name: Liu, K.
name: Yung, M. -H.
name: Sun, L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Spectroscopy is a crucial laboratory technique for understanding quantum systems through their interactions with electromagnetic radiation. Particularly, spectroscopy is capable of revealing the physical structure of molecules, leading to the development of the maser - the forerunner of the laser. However, real-world applications of molecular spectroscopy are mostly confined to equilibrium states, due to computational and technological constraints; a potential breakthrough can be achieved by utilizing the emerging technology of quantum simulation. Here we experimentally demonstrate that a superconducting quantum simulator is capable of generating molecular spectra for both equilibrium and non-equilibrium states, reliably producing the vibronic structure of the molecules. Furthermore, our quantum simulator is applicable not only to molecules with a wide range of electronic-vibronic coupling strength characterized by the Huang-Rhys parameter, but also to molecular spectra not readily accessible under normal laboratory conditions. These results point to a new direction for predicting and understanding molecular spectroscopy, exploiting the power of quantum simulation.
CВЕРХПРОВОДИМОСТЬ В ПОЛИГИДРИДАХ МЕТАЛЛОВ ВБЛИЗИ КОМНАТНОЙ ТЕМПЕРАТУРЫ. СОВРЕМЕННОЕ СОСТОЯНИЕ И НОВЫЕ РЕЗУЛЬТАТЫ
Creators: name: Троян И.А.
name: Любутин И.С.
name: Иванова А.Г.
name: Пудалов В. М.
name: Садаков А.В.
name: Семенок Д.В.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: Представлены новые экспериментальные результаты по исследованию сверхпроводимости в некоторых полигидридах металлов при статических давлениях мультимегабарного диапазона.
Affordable, Rapid Bootstrapping of the Space Industry and Solar System Civilization
Creators: name: Metzger, Philip T.
name: Muscatello, Anthony
name: Mueller, Robert P.
name: Mantovani, James
Publisher: name: arXiv
Year: 2016
Subjects: subject: Popular Physics (physics.pop-ph)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Advances in robotics and additive manufacturing have become game-changing for the prospects of space industry. It has become feasible to bootstrap a self-sustaining, self-expanding industry at reasonably low cost. Simple modeling was developed to identify the main parameters of successful bootstrapping. This indicates that bootstrapping can be achieved with as little as 12 metric tons (MT) landed on the Moon during a period of about 20 years. The equipment will be teleoperated and then transitioned to full autonomy so the industry can spread to the asteroid belt and beyond. The strategy begins with a sub-replicating system and evolves it toward full self-sustainability (full closure) via an in situ technology spiral. The industry grows exponentially due to the free real estate, energy, and material resources of space. The mass of industrial assets at the end of bootstrapping will be 156 MT with 60 humanoid robots, or as high as 40,000 MT with as many as 100,000 humanoid robots if faster manufacturing is supported by launching a total of 41 MT to the Moon. Within another few decades with no further investment, it can have millions of times the industrial capacity of the United States. Modeling over wide parameter ranges indicates this is reasonable, but further analysis is needed. This industry promises to revolutionize the human condition.
description: 24 pages, 14 figures
A Circumbinary Disk Scenario For The Negative Orbital-Period Derivative Of The Ultracompact X-ray Binary 4u1820-303
Creators: name: Jiang, Long
name: Chen, Wen-Cong
name: Li, Xiang-dong
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: It is generally thought that an ultracompact X-ray binary is composed with a neutron star and a helium white dwarf donor star. As one of the most compact binaries, 4U 1820-303 in globular cluster NGC 6624 was predicted an orbital-period derivative at a rate of $\dot{P}/P\sim1.1\times10^{-7}$ ${\rm yr^{-1}}$ if the mass transfer is fully driven by gravitational radiation. However, the recent analysis of the 16 ${\rm yr}$ data from \textit{Rossi X-ray Timing Explorer} and other historical records yielded a negative orbital-period derivative in the past $35$ yr. In this work, we propose an evolutionary circumbinary (CB) disk model to account for this anomalous orbital-period derivative. 4U 1820-30 was known to undergo superbust events caused by runaway thermal nuclear burning on the neutron star. We assume that for a small fraction of the superbursts, part of the ejected material may form a CB disk around the binary. If the recurrence time of such superbursts is $\sim10,000$ yr and $\sim10$% of the ejected mass feeds a CB disk, the abrupt angular-momentum loss causes a temporary orbital shrink, and the donor's radius and its Roche-lobe radius do not keep in step. Driven by mass transfer and angular-momentum loss, the binary would adjust its orbital parameters to recover a new stable stage. Based on the theoretical analysis and numerical simulation, we find that the required feed mass at the CB disk is approximately $\sim 10^{-8}$ ${\rm M_{\odot}}$.
description: 7 pages, 4 figures, accepted for publication by ApJ
DFT ИССЛЕДОВАНИЯ МАГНИТОЭЛЕКТРИЧЕСКИХ СВОЙСТВ ГЕТЕРОСТРУКТУР ФЕРРОМАГНЕТИК/СЕГНТОЭЛЕКТРИК
Creators: name: Мамин Р. Ф.
name: Евсеев К. В.
name: Гумарова И. И.
name: Камашев А. А.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: В настоящей работе с помощью расчетов на основе теории функционала плотности (DFT density functional theory) были исследованы пленочные гетероструктуры Fe/BaTiO3, Fe/SrTiO3, Co/BaTiO3, Co/SrTiO3.
EVOLUTION OF SURFACE CONDUCTIVITY IN SmB6 UNDER NONMAGNETIC (Yb2+) AND MAGNETIC (Eu2+) DOPING
Creators: name: Anisimov, M.
name: Zhurkin, V.
name: Voronov, V.
name: Bogach, A.
name: Bozhko, A.
name: Demishev, S.
name: Shitsevalova, N.
name: Gabáni, S.
name: Flachbart, K.
name: Glushkov, V.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: Here we report a comparative research of magnetotransport (resistivity and transverse magnetoresistance) measured on high quality single crystals of YbxSm1xB6 and EuxSm1-xB6 solid solutions (x ≤ 0.05) at temperatures 1.7 − 300 K in magnetic fields up to 82 kOe.
Probando again
Creators: name: Martin, Roberto
Publisher: name: figshare
Year: 2017
Subjects: subject: 79901 Agricultural Hydrology (Drainage, Flooding, Irrigation, Quality, etc.)
subject: FOS: Other agricultural sciences
subject: 170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
subject: FOS: Psychology

description: Probando como se usa este chisme
Diversity of hysteresis in a fully cooperative coinfection model
Creators: name: Rodríguez, Jorge P.
name: Liang, Yu-Hao
name: Juang, Jonq
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: We propose a fully cooperative coinfection model in which singly infected individuals are more likely to acquire a second disease than those who are susceptible, and doubly infected individuals are also assumed to be more contagious than those infected with one disease. The dynamics of such fully cooperative coinfection model between two interacting infectious diseases is investigated through well-mixed and network-based approaches. We show that the former approach exhibits three types of hysteresis, namely, $C$, $S_l$ and $S_r$ types, where the last two types have not been identified before. The first (resp., the second and the third) type exhibits (resp., exhibit) discontinuous outbreak transition from the disease free (resp., low prevalence) state to the high prevalence state when a transmission rate crosses a threshold from the below. Moreover, the third (resp., the first and the second) type possesses (resp., possess) discontinuous eradication transition from the high prevalence state to the low prevalence (resp., disease free) state when the transmission rate reaches a threshold from the above. Complete characterization of these three types of hysteresis in term of parameters measuring the uniformity of the model is also provided. Finally, we assess numerically this epidemic dynamics in random networks.
description: 10 pages, 12 figures
LOW TEMPERATURE HIGH FREQUENCY EPR ABSORPTION OF Fe45Co30Si10B15 MICROWIRE
Creators: name: Shestakov, A.V.
name: Semeno, A.V.
name: Demishev, S.V.
name: Rodionova, V.V.
name: Kolesnikova, V.G.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: Using the high frequency (60 GHz) EPR, microwave (MW) absorption spectra were obtained at temperatures from 4.2 to 30 K and in magnetic fields up to 40 kOe.
Roborovski hamster (Phodopus roborovskii) strain SH101 as a systemic infection model of SARS-CoV-2
Creators: name: Zhai, Chongkai
name: Wang, Mingda
name: Chung, Hea-Jong
name: Hassan, Mehedi
name: Lee, Seungkoo
name: Kim, Hyeon-Jin
name: Hong, Seong-Tshool
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Severe acute respiratory syndrome CoV-2 (SARS-CoV-2) is currently causing a worldwide threat with its unusually high transmission rates and rapid evolution into diverse strains. Unlike typical respiratory viruses, SARS-CoV-2 frequently causes systemic infection by breaking the boundaries of the respiratory systems. The development of animal models recapitulating the clinical manifestations of COVID-19 is of utmost importance not only for the development of vaccines and antivirals but also for understanding the pathogenesis. However, there has not been developed an animal model for systemic infection of SARS-CoV-2 representing most aspects of the clinical manifestations of COVID-19 with systemic symptoms. Here we report that a Roborovski hamster strain SH101, a laboratory inbred hamster strain of P. roborovskii, displayed most symptoms of systemic infection upon SARS-CoV-2 infection as in the case of the human counterpart, unlike current COVID-19 animal models. Roborovski hamster strain SH101 post-infection of SARS-CoV-2 represented most clinical symptoms of COVID-19 such as snuffling, labored breathing, dyspnea, cough, hunched posture, progressive weight loss, ruffled fur, and high fever following shaking chills. Histological examinations also revealed initial right-predominated pneumonia as well as slight organ damages in the brain and liver, manifesting systemic COVID-19 cases. Considering the merit of a small animal as well as its clinical manifestations of SARS-CoV-2 infection in human, this hamster model seems to provide an ideal tool to investigate COVID-19.
INVESTIGATION OF MULTICOMPONENT DUSTY PLASMA IN THE DC GLOW DISCHARGE AT TEMPERATURES BELOW 2 K
Creators: name: Boltnev, R.E.
name: Kononov, E.A.
name: Vasiliev, M.M.
name: Trukhachev, F.M.
name: Petrov, O.F.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: Multimodal dusty plasma in a positive column of the direct current (DC) glow discharge at temperatures 1.4 ÷ 2.1 K has been studied experimentally and theoretically for the first time.
title: ADCO, Cart. 186 (11 H 71), f. 0269v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la Côte-d'Or, C
art. 186 (11 H 71). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la
 Côte-d'Or, Cart. 186 (11 H 71), f. 0269v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-
project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Scalable distributed HEMT model for millimetre-wave applications
Creators: name: Hoque, Shah Md Eahteshamul
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: A scalable HEMT model is highly desirable for device engineers. Modern electronic devices require scalability up to high frequencies and device engineers need more flexibility to design complex circuits. For high-frequency applications the scalable model should be able to accurately predict behaviour of the device. The major drawback is lack of a proper topology to represent a full device of any size and inaccurate techniques to separate the parameters from the measured data. This thesis explores a distributed model of a HEMT and gives an error-free linear scaling technique for the extrinsic parameters of the device. A new technique was introduced to separate the access network from the active device, and the active device was modelled using a distributed technique. A new topology of unit cell is proposed, which can be used to analyse different HEMT devices and predict the behaviour of unmeasured devices sizes for high frequencies. This model also includes the distributed effects for various widths of devices, where a signal is propagated from the gate to drain metallisation. The effect of the manifold in a distributed model is explored for various widths of devices and a figure of merit of the model is discussed. The linear scalable model was applied to compound devices, varying in the number of fingers and widths, and showed excellent agreement. The effects of the manifold on these HEMTs are explained with respect to the gain of the devices. The model is also used to analyse the drain-current behaviour of a HEMT and establishes linear relationships for the drain current in terms of the unit cell and device metallisation. The model is applied to the determination of the maximum achievable gain-bandwidth product as a function of gate width. This defines the upper limit of achievable performance for further work, and a new and improved manifold and finger layouts.
LOW-TEMPERATURE NONPARABOLIC MAGNETORESISTANCE IN HoTe3
Creators: name: Voropaev, D.M.
name: Cohn, I.A.
name: Tyumentsev, M.M.
name: Grigoriev, P.D.
name: Zaitsev-Zotov, S.V.
name: Pachoud, E.
name: Hadj-Azzem, A.
name: Monceau, P.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: Here we present our results of studying the transverse MR of this HoTe3 compound at significantly lower temperatures up to 2.8 K for two perpendicular directions in magnetic fields up to 7 T.
Dimensions of sets which uniformly avoid arithmetic progressions
Creators: name: Fraser, Jonathan M.
name: Saito, Kota
name: Yu, Han
Publisher: name: arXiv
Year: 2017
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Combinatorics (math.CO)
subject: Metric Geometry (math.MG)
subject: FOS: Mathematics
subject: 11B25, 28A80

description: We provide estimates for the dimensions of sets in $\mathbb{R}$ which uniformly avoid finite arithmetic progressions. More precisely, we say $F$ uniformly avoids arithmetic progressions of length $k \geq 3$ if there is an $ε>0$ such that one cannot find an arithmetic progression of length $k$ and gap length $Δ>0$ inside the $εΔ$ neighbourhood of $F$. Our main result is an explicit upper bound for the Assouad (and thus Hausdorff) dimension of such sets in terms of $k$ and $ε$. In the other direction, we provide examples of sets which uniformly avoid arithmetic progressions of a given length but still have relatively large Hausdorff dimension. We also consider higher dimensional analogues of these problems, where arithmetic progressions are replaced with arithmetic patches lying in a hyperplane. As a consequence we obtain a discretised version of a `reverse Kakeya problem': we show that if the dimension of a set in $\mathbb{R}^d$ is sufficiently large, then it closely approximates arithmetic progressions in every direction.
description: 8 pages
Chiral edge fluctuations of colloidal membranes
Creators: name: Jia, Leroy L.
name: Zakhary, Mark J.
name: Dogic, Zvonimir
name: Pelcovits, Robert A.
name: Powers, Thomas R.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We study edge fluctuations of a flat colloidal membrane comprised of a monolayer of aligned filamentous viruses. Experiments reveal that a peak in the spectrum of the in-plane edge fluctuations arises for sufficiently strong virus chirality. Accounting for internal liquid crystalline degrees of freedom by the length, curvature, and geodesic torsion of the edge, we calculate the spectrum of the edge fluctuations. The theory quantitatively describes the experimental data, demonstrating that chirality couples in-plane and out-of-plane edge fluctuations to produce the peak.
description: Main text: 4 pages, 2 figures. Supplementary materials: 3 videos
Building and Sustaining a Grassroots Library Organization: A Three Year Retrospective of Library Pipeline
Creators: name: Finnell, Joshua
name: Konkiel, Stacy
Publisher: name: figshare
Year: 2018
Subjects: subject: 80799 Library and Information Studies not elsewhere classified
subject: FOS: Media and communications

description: This article is an overview of Library Pipeline, a grassroots library organization dedicated to supporting structural changes by providing opportunities, funding, and services that improve the library as an institution and librarianship as a profession.
Building and Sustaining a Grassroots Library Organization A Three Year Retrospective of Library Pipeline.pdf
Creators: name: Finnell, Joshua
name: Konkiel, Stacy
Publisher: name: figshare
Year: 2017
Subjects: subject: 80799 Library and Information Studies not elsewhere classified
subject: FOS: Media and communications

description: This article is an overview of Library Pipeline, a grassroots library organization dedicated to supporting structural changes by providing opportunities, funding, and services that improve the library as an institution and librarianship as a profession.
Additional file 1 of A blood microRNA classifier for the prediction of ICU mortality in COVID-19 patients: a multicenter validation study
Creators: name: de Gonzalo-Calvo, David
name: Molinero, Marta
name: Benítez, Iván D.
name: Perez-Pons, Manel
name: García-Mateo, Nadia
name: Ortega, Alicia
name: Postigo, Tamara
name: García-Hidalgo, María C.
name: Belmonte, Thalia
name: Rodríguez-Muñoz, Carlos
name: González, Jessica
name: Torres, Gerard
name: Gort-Paniello, Clara
name: Moncusí-Moix, Anna
name: Estella, Ángel
name: Tamayo Lomas, Luis
name: Martínez de la Gándara, Amalia
name: Socias, Lorenzo
name: Peñasco, Yhivian
name: de la Torre, Maria Del Carmen
name: Bustamante-Munguira, Elena
name: Gallego Curto, Elena
name: Martínez Varela, Ignacio
name: Martin Delgado, María Cruz
name: Vidal-Cortés, Pablo
name: López Messa, Juan
name: Pérez-García, Felipe
name: Caballero, Jesús
name: Añón, José M.
name: Loza-Vázquez, Ana
name: Carbonell, Nieves
name: Marin-Corral, Judith
name: Jorge García, Ruth Noemí
name: Barberà, Carmen
name: Ceccato, Adrián
name: Fernández-Barat, Laia
name: Ferrer, Ricard
name: Garcia-Gasulla, Dario
name: Lorente-Balanza, Jose Ángel
name: Menéndez, Rosario
name: Motos, Ana
name: Peñuelas, Oscar
name: Riera, Jordi
name: Bermejo-Martin, Jesús F.
name: Torres, Antoni
name: Barbé, Ferran
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1
Impact of URI Canonicalization on Memento Count
Creators: name: Kelly, Mat
name: Alkwai, Lulwah M.
name: Nelson, Michael L.
name: Weigle, Michele C.
name: Van de Sompel, Herbert
Publisher: name: arXiv
Year: 2017
Subjects: subject: Digital Libraries (cs.DL)
subject: FOS: Computer and information sciences

description: Quantifying the captures of a URI over time is useful for researchers to identify the extent to which a Web page has been archived. Memento TimeMaps provide a format to list mementos (URI-Ms) for captures along with brief metadata, like Memento-Datetime, for each URI-M. However, when some URI-Ms are dereferenced, they simply provide a redirect to a different URI-M (instead of a unique representation at the datetime), often also present in the TimeMap. This infers that confidently obtaining an accurate count quantifying the number of non-forwarding captures for a URI-R is not possible using a TimeMap alone and that the magnitude of a TimeMap is not equivalent to the number of representations it identifies. In this work we discuss this particular phenomena in depth. We also perform a breakdown of the dynamics of counting mementos for a particular URI-R (google.com) and quantify the prevalence of the various canonicalization patterns that exacerbate attempts at counting using only a TimeMap. For google.com we found that 84.9% of the URI-Ms result in an HTTP redirect when dereferenced. We expand on and apply this metric to TimeMaps for seven other URI-Rs of large Web sites and thirteen academic institutions. Using a ratio metric DI for the number of URI-Ms without redirects to those requiring a redirect when dereferenced, five of the eight large web sites' and two of the thirteen academic institutions' TimeMaps had a ratio of ratio less than one, indicating that more than half of the URI-Ms in these TimeMaps result in redirects when dereferenced.
description: 43 pages, 8 figures
Automatic segmentation of MR brain images with a convolutional neural network
Creators: name: Moeskops, Pim
name: Viergever, Max A.
name: Mendrik, Adriënne M.
name: de Vries, Linda S.
name: Benders, Manon J. N. L.
name: Išgum, Ivana
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Automatic segmentation in MR brain images is important for quantitative analysis in large-scale studies with images acquired at all ages. This paper presents a method for the automatic segmentation of MR brain images into a number of tissue classes using a convolutional neural network. To ensure that the method obtains accurate segmentation details as well as spatial consistency, the network uses multiple patch sizes and multiple convolution kernel sizes to acquire multi-scale information about each voxel. The method is not dependent on explicit features, but learns to recognise the information that is important for the classification based on training data. The method requires a single anatomical MR image only. The segmentation method is applied to five different data sets: coronal T2-weighted images of preterm infants acquired at 30 weeks postmenstrual age (PMA) and 40 weeks PMA, axial T2- weighted images of preterm infants acquired at 40 weeks PMA, axial T1-weighted images of ageing adults acquired at an average age of 70 years, and T1-weighted images of young adults acquired at an average age of 23 years. The method obtained the following average Dice coefficients over all segmented tissue classes for each data set, respectively: 0.87, 0.82, 0.84, 0.86 and 0.91. The results demonstrate that the method obtains accurate segmentations in all five sets, and hence demonstrates its robustness to differences in age and acquisition protocol.
Direct and Indirect Effects Based on Difference-in-Differences With an Application to Political Preferences Following the Vietnam Draft Lottery
Creators: name: Deuchert, Eva
name: Huber, Martin
name: Schelker, Mark
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: We propose a difference-in-differences approach for disentangling a total treatment effect within specific subpopulations into a direct effect and an indirect effect operating through a binary mediating variable. Random treatment assignment along with specific common trend and effect homogeneity assumptions identify the direct effects on the always and never takers, whose mediator is not affected by the treatment, as well as the direct and indirect effects on the compliers, whose mediator reacts to the treatment. In our empirical application, we analyze the impact of the Vietnam draft lottery on political preferences. The results suggest that a high draft risk due to the draft lottery outcome leads to an increase in mild preferences for the Republican Party, but has no effect on strong preferences for either party or on specific political attitudes. The increase in Republican support is mostly driven by the direct effect not operating through the mediator that is military service.
Functional analysis of seven regulators of G protein signaling (RGSs) in the nematode-trapping fungus Arthrobotrys oligospora
Creators: name: Ma, Ni
name: Zhao, Yining
name: Wang, Yunchuan
name: Yang, Le
name: Li, Dongni
name: Yang, Jiangliu
name: Jiang, Kexin
name: Zhang, Ke-Qin
name: Yang, Jinkui
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Regulators of G protein signaling (RGSs) are proteins that negatively regulate G protein signal transduction. In this study, seven putative RGSs were characterized in the nematode-trapping (NT) fungus, Arthrobotrys oligospora. Deleting Rgs genes significantly increased intracellular cAMP levels, and caused defects in mycelia growth, stress resistance, conidiation, trap formation, and nematocidal activity. In particular, the ΔAoFlbA mutant was unable to produce conidia and traps. Transcriptomic analysis showed that amino acid metabolic and biosynthetic processes were significantly enriched in the ΔAoFlbA mutant compared to WT. Interestingly, Gas1 family genes are significantly expanded in A. oligospora and other NT fungi that produce adhesive traps, and are differentially expressed during trap formation in A. oligospora. Disruption of two Gas1 genes resulted in defective conidiation, trap formation, and pathogenicity. Our results indicate that RGSs play pleiotropic roles in regulating A. oligospora mycelial growth, development, and pathogenicity. Further, AoFlbA is a prominent member and required for conidiation and trap formation, possibly by regulating amino acid metabolism and biosynthesis. Our results provide a basis for elucidating the signaling mechanism of vegetative growth, lifestyle transition, and pathogenicity in NT fungi.
Impurity- and Magnetic-field-induced Quasiparticle States in Chiral $p$-wave Superconductors
Creators: name: Guo, Yao-Wu
name: Li, Wei
name: Chen, Yan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Both impurity- and magnetic-field-induced quasiparticle states in chiral $p$-wave superconductors are investigated theoretically by solving the Bogoliubov--de Gennes equations self-consistently. At the strong scattering limit, we find that a universal state bound to the impurity can be induced for both a single nonmagnetic impurity and a single magnetic impurity. Furthermore, we find that different chiral order parameters and the corresponding supercurrents have uniform distributions around linear impurities. Calculations of the local density of states in the presence of an external magnetic field show that the intensity peak of the zero-energy Majorana mode in the vortex core can be enhanced dramatically by tuning the strength of the external magnetic field or pairing interaction.
description: 7 pages, 7 figures
Additional file 2 of A blood microRNA classifier for the prediction of ICU mortality in COVID-19 patients: a multicenter validation study
Creators: name: de Gonzalo-Calvo, David
name: Molinero, Marta
name: Benítez, Iván D.
name: Perez-Pons, Manel
name: García-Mateo, Nadia
name: Ortega, Alicia
name: Postigo, Tamara
name: García-Hidalgo, María C.
name: Belmonte, Thalia
name: Rodríguez-Muñoz, Carlos
name: González, Jessica
name: Torres, Gerard
name: Gort-Paniello, Clara
name: Moncusí-Moix, Anna
name: Estella, Ángel
name: Tamayo Lomas, Luis
name: Martínez de la Gándara, Amalia
name: Socias, Lorenzo
name: Peñasco, Yhivian
name: de la Torre, Maria Del Carmen
name: Bustamante-Munguira, Elena
name: Gallego Curto, Elena
name: Martínez Varela, Ignacio
name: Martin Delgado, María Cruz
name: Vidal-Cortés, Pablo
name: López Messa, Juan
name: Pérez-García, Felipe
name: Caballero, Jesús
name: Añón, José M.
name: Loza-Vázquez, Ana
name: Carbonell, Nieves
name: Marin-Corral, Judith
name: Jorge García, Ruth Noemí
name: Barberà, Carmen
name: Ceccato, Adrián
name: Fernández-Barat, Laia
name: Ferrer, Ricard
name: Garcia-Gasulla, Dario
name: Lorente-Balanza, Jose Ángel
name: Menéndez, Rosario
name: Motos, Ana
name: Peñuelas, Oscar
name: Riera, Jordi
name: Bermejo-Martin, Jesús F.
name: Torres, Antoni
name: Barbé, Ferran
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 2
MAGNETIC STATE OF COBALT IN LAYERED CHALCOGENIDES Co7(Se,Te)8 AND Fe4Co3Se8
Creators: name: Piskunov Yu.V.
name: Ogloblichev, V.V.
name: Sadykov, A.F.
name: Akramov, D.F.
name: Smol’Nikov, A.G.
name: Gerashchenko, A.P.
name: Selezneva, N.V.
name: Baranov, N.V.
Publisher: name: 39-е Совещание по физике низких температур (Международная конференция), посвященное 300-летию Российской академии наук
Year: 2024
Subjects: Физика низких температур

description: In this work the structural and magnetic properties of the Co7Se8, Co7Te8 and Fe4Co3Se8 compounds have been studied using X-ray diffraction, measurements of the magnetic susceptibility, and NMR spectroscopy on 59Co nuclei.