cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hepatoprotective properties of Gentiana SPP: Against non-alcoholic fatty liver disease (NAFLD)
Creators: name: Boateng, Anthony
Publisher: name: University of Westminster
Year: 2018

description: Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterised by the accumulation of fat in the liver. It is estimated that 33 % of the UK population have NAFLD with 2-5 % progressing to non-alcoholic steatohepatitis (NASH). Due to a lack of an outright therapy for NAFLD, treatment has been mainly focussed on managing the conditions associated with the disease such as obesity, diabetes mellitus and hyperlipidaemia. This study aimed to investigate the means by which hepatocyte protection is conferred by Gentiana plants (Gentiana lutea, Gentiana macrophylla, Gentiana scabra and Gentiana rigescens) used in herbal medicine for the management of non-alcoholic fatty liver diseases (NAFLD). The role played by some of the inherent Gentiana phytochemicals including: gentiopicroside, sweroside and swertiamarin in promoting hepatocyte protection against the cytotoxic effects of fatty acids were also investigated. Gentiana species: lutea, macrophylla, rigescens, and scabra are known to protect and enhance hepatocyte viability via their antioxidant, anti-inflammatory and bitter components including: amarogentin gentianine, iso-orientin, swertiamarin, gentiopicroside, and sweroside. This study was necessitated due to a lack of adequate research on the hepatoprotective effects of the above-named Gentiana species and phytochemicals with special emphasis on their effect on mitochondrial respiration in the presence of fatty acids. At the time of submission, this was the first study to utilise the seahorse mitochondria stress assay to investigate the Gentiana species as well as phytochemicals: gentiopicroside, sweroside and swertiamarin. It was also found that the most abundant phytochemical in all four Gentiana species was gentiopicroside (up to 4.6% g/g), followed by swertiamarin (0.21–0.45% g/g), and sweroside (0.03- 0.4 % g/g). Furthermore, it was also observed that the methanolic extracts of all four Gentiana protected HepG2 and THLE-2 cells by inhibiting arachidonic acid from diminishing cell replication but showed a mitogenic effect mostly observed in gentiopicroside, Gentiana lutea and Gentiana macrophylla. It was concluded that phytochemicals: gentiopicroside, sweroside and swertiamarin play key roles in the hepatocyte protection exerted by methanolic extracts of Gentiana lutea, Gentiana macrophylla, Gentiana scabra and Gentiana rigescens against the cytotoxic effects of fatty acids. This protection is conferred by enhancing mitochondrial function in terms of increasing maximal respiratory capacity in response to high influx of fatty acids, promoting ATP production as well as scavenging ROS produced as a result of high fatty acid influx and increased mitochondrial respiration. However, the mitogenic effect observed in gentiopicroside and Gentiana macrophylla requires further studies using unmodified primary hepatocytes to gain better understanding.
Predicted multiply-imaged X-ray AGNs in the XXL survey
Creators: name: Finet, F.
name: Elyiv, A.
name: Melnyk, O.
name: Wertz, O.
name: Horellou, C.
name: Surdej, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We estimate the incidence of multiply-imaged AGNs among the optical counterparts of X-ray selected point-like sources in the XXL field. We also derive the expected statistical properties of this sample, such as the redshift distribution of the lensed sources and of the deflectors that lead to the formation of multiple images, modelling the deflectors using both spherical (SIS) and ellipsoidal (SIE) singular isothermal mass distributions. We further assume that the XXL survey sample has the same overall properties as the smaller XMM-COSMOS sample restricted to the same flux limits and taking into account the detection probability of the XXL survey. Among the X-ray sources with a flux in the [0.5-2] keV band larger than 3.0x10$^{-15}$ erg cm$^{-2}$ s$^{-1}$ and with optical counterparts brighter than an r-band magnitude of 25, we expect ~20 multiply-imaged sources. Out of these, ~16 should be detected if the search is made among the seeing-limited images of the X-ray AGN optical counterparts and only one of them should be composed of more than two lensed images. Finally, we study the impact of the cosmological model on the expected fraction of lensed sources.
description: 15 pages, 7 figures, 1 table, accepted for publication in MNRAS
The Holy Spirit and prayer in the letters of Paul
Creators: name: Stone, Jesse D.
Publisher: name: The University of St Andrews
Year: 2023
Subjects: subject: Holy Spirit
subject: Paul
subject: Biblical studies
subject: New Testament
subject: Prayer
subject: Religious experience
subject: Theology
subject: Pneumatology
subject: Romans
subject: Galatians
subject: 1 Corinthians
subject: BS2655.H67S8
subject: Bible. Epistles of Paul--Criticism, interpretation, etc.
subject: Holy Spirit--Biblical teaching

description: The present thesis is the first monograph-length study of the pneumatic prayers in the letters of Paul. Paul mentions three experiences where the spirit inspires prayer: the Abba cry (Gal 4.6; Rom 8.15–16), prayer in tongues (1 Cor 14.14–15), and the spirit’s intercession (Rom 8.26–27). While each of these passages has received substantial attention from previous generations of Pauline scholarship, their precise meaning and significance remain contested. Even more controversial is their potential relation to each other. This thesis aims to propose a taxonomy for these pneumatic prayers based on their shared descriptive features and common connections to other aspects of Paul’s theology. Descriptively, I argue that Paul describes pneumatic prayers as common and perceptible experiences of inspired speech for early Christians. Theologically, I contend that Paul believed pneumatic prayers signified the eschatological time in which believers live and bore witness to believers’ new glorified filial status as they participated in the prayers and worship of heavenly beings.
Assessment of Rural Water Supply System for Domestic Use in Menz Keya Gebriel Woreda, North Shewa Zone, Amhara Region, Ethiopia
Creators: name: Genzeb Goremis
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2022
Subjects: Water supply system, Water demand, Sources of water, water quality

description: Water is one of our most valuable resources and it’s supremely important for human
 survival. The aim of this study was to assess rural water supply system for domestic use
 of Menz Keya Gebriel Woreda, North Shewa Zone in Amhara region, Ethiopia. This
 study used both qualitative and quantitative method. Data were collected from primary
 and secondary sources. The collected data were analyzed using Statistical Package for
 Social Sciences version 20.0 (SPSSV.20.0), linear regression model, ArcMap10.4.1,
 Bentley WaterCAD(SECECTED serious 6) and Laboratory tests (Planitest® Photometer
 7100 and filtration aerobic plate count test) were used to see the quality of the water. The
 study showed that there is inadequate improved water sources, lack of accessibility due
 to water points are located far from the households, most water point settings are
 sparsely, some points are near each other and the sources of water for domestic use of
 participant households was spring (32.9 %) next to on- spot spring developed (33.4%).
 The approximate distance of water source from the house (49.9%) and time taken to fetch
 water (47.5%) of household respondent had reported to be 1-1.5 kilometers and 30 to 60
 minutes respectively. The total domestic water demand at the end of the year 2039 would
 be 1.78 Million cubic meters. The maximum and minimum pressure head of hydraulic
 analysis was 69m and 20m respectively. The Physicio-chemical parameters results were
 almost safe except turbidity at sample location S4, S5, and S8, hardness at sample
 location S5, potassium and total coliform bacteria at sample location S7, S9 and S10 were
 null. The study concluded that water supply system for domestic use is faced with major
 challenges like inadequate improved water sources, lack of accessibility, lack of skilled
 manpower, lack of groundwater, and topographical problem, no transportation, and
 drought. To have adequate and sustainable water supply for the community the Woreda
 Water and Energy Bureau had better to develop new additional water schemes with pump
 along with repair and rehabilitating non- functional, build a storage reservoir within
 reasonable distances from two or more water sources, made privet house connection
 system and use household rainwater harvesting system are better to meet future water
 demand of the Woreda.
Impact of transplant cell population on locomotor recovery after experimental spinal cord injury – a systematic review and meta-analysis
Creators: name: Prager, Jon
name: Clarke, Abi
name: Wilkinson, Aimee
name: Priest, Sebastian
name: Granger, Nicolas
name: Wong, Liang-Fong
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medical Sciences
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Medicine and Health Sciences
subject: Cell Transplantation
subject: Meta-analysis
subject: Spinal Cord Injury

description: A pre-registration of the methods to be used in the decribed meta-analysis.
Sequences of Sexual Initiation and Subsequent Depression Among Adolescents
Creators: name: Reese, Bianka
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Objectives: To determine if sequence of sexual initiation (i.e., initiating oral-genital, anal, or vaginal sex first) predicts subsequent levels of depressive symptoms. Methods: Data come from Waves I-IV of the National Longitudinal Study of Adolescent Health. Multiple linear regression models are used to assess the association between sexual initiation sequence and subsequent depression. Interactions between sequence of initiation and stressful life events (SLEs) are also examined. Results: In comparison to females who initiated vaginal sex first, as the number of SLEs increased, initiating anal sex first is associated with an increase of 2.65 in the number depressive symptoms (ranges from 0-27). Conclusions: Findings suggest that how adolescents begin their sexual lives may have important implications for mental health outcomes. Failure to include oral-genital and anal sex in studies of adolescent sexual behavior may undermine efforts to understand how patterns of early sexual behavior contribute to the high rates of depression among adolescents.
Reflections on planning: Pennsylvania vs. Ontario
Creators: name: Ball, Jennifer
name: Brockie, Emily
name: Caldwell, Wayne J.
name: Marks, Joanne
name: Nelson, Mike
name: Parsons, Jay
name: Rudy, Harold
name: Stonehouse, Shawna
name: Weber, Sandra
name: Weir, Claire
name: Williams, Melanie
Publisher: name: Vancouver Island University - Royal Roads University
Year: 2002
Subjects: subject: City planning--Ontario
subject: City planning--Pennsylvania
subject: City planning--Citizen participation
subject: Agriculture and state--Pennsylvania

description: This article compares a number of rural planning issues and approaches in Pennsylvania and Ontario. The discussion focuses on issues related to the preservation of agricultural lands, urban growth boundaries, property rights, and the role of local and state/ provincial government. In Pennsylvania, extensive citizen involvement has led to a high level of public "ownership" of planning. Planning in Pennsylvania has also made significant progress in the use of voluntary programs and finan cial incentives, such as the purchase of development rights to protect agricultural lands. Compared with Ontario, however, the use of planning regulations in rural areas has been less successful, providing much less coordination of these regulations at the local, county and state levels.
description: Cet article compare les approches et pratiques en matière d'urbanisme rural entre la Pennsylvanie et l'Ontario. Le sujet met de l'avant les questions relatives à la préservation des terres agricoles, aux limites de la croissance urbaine, aux droits de propriété ainsi que le rôle des autorités locales, et de l'État au du Gouvernement provincial. En Pennsylvanie, l'engagement de la population a abouti sur une véritable appropriation de l'urbanisme par le public, et des progrès importants ont été faits en matière d'initiatives et de mesures incitatives afin de protéger le territoire agricole. Par contre l'utilisation des règlements d'urbanisme en matière rurale a connu moins de succès qu'en Ontario en raison d'une plus faible coordination de ces règlements aux niveaux locaux, de comtés et de l'état.
description: Abstract in English and French; text in English
description: https://viurrspace.ca/bitstream/handle/10613/5462/Article009.pdf?sequence=3
Mechanistic Studies of Thiol Additions to Electrophilic Warheads
Creators: name: Watt, Sarah
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2023
Subjects: acrylamide
chloroacetamide
Michael-addition
SN2
glutathione
thiol-addition

description: Targeted covalent inhibitors (TCIs) are irreversible enzyme inhibitors that are designed to first bind to a targeted enzyme’s active site reversibly using non-covalent interactions between the molecular scaffold of the inhibitor and the surrounding amino acid residues of the enzyme’s binding site. They then form a covalent bond between the inhibitor’s electrophilic warhead and a nucleophilic amino acid residue located inside of the binding pocket. Cysteine (Cys), a redox-sensitive thiol, is found in many enzyme active sites and is used as the target for many current TCIs in clinical application. Electrophilic warheads such as acrylamides and chloroacetamides are known to readily undergo thiol-addition, and although they are commonly used in the development of enzyme inhibitors, few previous studies have explored the mechanism of thiol-addition and the intrinsic reactivities of these moieties. In this work, a robust kinetic assay was developed to perform mechanistic studies of thiol-addition to the electrophilic warhead derivatives N-phenylacrylamide (NPA), N-acryloylpiperidine (AcrPip), and N-phenylchloroacetamide (NPC). By reacting these warhead derivatives with thiol nucleophiles having various pKa values, we were able to construct Brønsted-type plots, resulting in shallow positive βNucRS- values for NPA, AcrPip and NPC (βNucRS- = 0.07 ± 0.04, 0.11 ± 0.03, and 0.21 ± 0.07, respectively), meaning that these electrophiles are relatively insensitive to thiolate nucleophilicity. However, while the trend in their reactivity across thiolate nucleophilicity is similar, their intrinsic reactivity was found to be vastly different. In conjunction with the Brønsted-type plot, temperature, ionic strength, and kinetic isotope effects were studied to afford information about the rate-limiting transition state and elucidate the mechanism of thiol-addition. NPA and AcrPip were found to undergo very similar thiol-additions, consistent with the microscopic reverse of the E1cbrev elimination, whereas NPC follows an SN2 type addition, consistent with the intuitive mechanism of addition to a haloacetamide.
Peruvian experience: A planner's lot is not a happy one
Creators: name: Rotoff, Basil M.
Publisher: name: Vancouver Island University - Royal Roads University
Year: 2002
Subjects: subject: City planning--Peru
subject: Municipal government--Peru

description: Not long before the fall of the Fujimori government and the fateful earthquakes that shook southern Peru, the author was sent there by CESO (the Canadian Executive Services Organization) in order to study the region's municipal systems, assess the impact of the central government on municipal administrations, and establish the type of technical assistance Canada could provide. International agencies make their aid contingent upon democratization of local governments, so that the grants and loans intended for these governments are not highjacked. In the process of making this survey, the author couldn't fail to notice the difficult situation in which Peruvian municipal planners find themselves, especially in the face of the central government's arbitrary decrees, many of which are at odds with the nation's constitution. The government was diverting funds that legally belonged to the revenue of the municipalities, to great detriment of the quality of life. Let's hope that, under the new government of Alejandro Toledo, the situation will improve, and that our Peruvian colleagues will be free to practice planning as it should be.
description: Peu de temps avant la chute du gouvernement de Fuiimori et Jes tremblements de terre fatidiques qui ont secoué les villes du sud du Pérou, l'auteur avait été envoyé par la SACO dans ces memes villes dans le but d'étudier leur système municipal, d'évaluer l'impact du gouvernement central sur Jes gouvernements municipaux, et d'examiner le type d'aide technique que le Canada pourrait rendre aux municipalités. Les agences financières internationales insistent sur la démocratisation du pouvoir local afin de s'assurer que les prêts et octrois destinés aux gouvernements locaux ne soient escamotés avant d'atteindre leurs destinataires. Au cours de cette enquête, l'auteur a observé la situation difficile, sinon impossible, dans laquelle se trouvent les urbanistes municipaux face aux règlements et décrets arbitraires, contraires même à la Constitution du Pays, que leur impose le gouvernement central. Le gouvernement soutirait de plus en plus de fonds qui, de manière légitime, devaient revenir aux municipalités. La qualité de vie dans ces villes en souffrait énormément. Il faut espèrer qu'avec le nouveau gouvernemnt de Alexandre Toledo, la situation va s'améliorer, et que nos collègues péruviens pourront de nouveau poursuivre leur travail tel qu'il devrait être exercé.
description: Abstract in English and French; text in English.
description: https://viurrspace.ca/bitstream/handle/10613/5464/Article008.pdf?sequence=3
Whatever became of the public realm?
Creators: name: Sandalack, Bev
name: Nicolai, Andrei
Publisher: name: Vancouver Island University - Royal Roads University
Year: 2002
Subjects: subject: Land use, Urban
subject: City planning
subject: Public spaces

description: Much of our everyday urban existence occurs within the shared city spaces, defined by public and private buildings and made up of streets, sidewalks, parks and squares. This public realm facilitates urbanity, and our experience of the city is mostly of it. In recent decades, while the various actors involved in the development of urban form have been preoccupied with staking out their individual jurisdictions, the public realm has been neglected. Designers are too often focused on individual buildings and rarely consider the spaces in between, or are dealing largely with site-specific and market-driven projects. Development control bodies have assumed roles of land use administrators or policy makers, and as a result the public realm has been lost as a comprehensive area of inquiry and concern. A case needs to be made for a renewed concern and interest in the public realm as the deepest and longest lasting part of urban infrastructure.
description: Le quotidien urbain est vécu dans des espaces partagés, définis par des édifices publics et privés, des rues, des trottoirs des parcs et des places. Ces espaces publics encouragent l'urbanité et circonscrivent notre expérience de la ville. Depuis quelques décennies, les différents intervenants de l'espace urbain se sont affairés à délimiter leur territoire respectif au détriment du domaine public. Les concepteurs sont trop souvent préoccupés par les édifices et portent rarement attention aux espaces les délimitant, ou alors iIs conçoivent des projets spécifiques et provenant du sedeur privé. Les organismes de contrôle de l'aménagement ont assumé les rôles de décideurs et d'administrateurs de l'utilisation des sols, ce qui a eu pour effet de reléguer le domaine de la recherche et du développement des espaces publics aux oubliettes. Les espaces publics doivent reintegrer, dans l'urbanisme, la place essentielle qui leur revient dans l'infrastructure urbaine.
description: Abstract in English and French; text in English.
description: https://viurrspace.ca/bitstream/handle/10613/5465/Article007.pdf?sequence=3
Panel of Plasma Protein Biomarkers for Diagnosing Traumatic Brain Injury in Adults
Creators: name: Zafar, Umema
name: Habib, Syed Hamid
name: Bashir, Shahid
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Medical Sciences
subject: Medical Specialties
subject: Medical Physiology
subject: FOS: Basic medicine
subject: Neurology
subject: Medical Neurobiology
subject: Medicine and Health Sciences
subject: neurobiomarkers
subject: traumatic brain injury
subject: chronic brain damage

description: The implications of Traumatic Brain Injury (TBI) going unnoticed can be debilitating. TBI symptoms generally develop years after the initial injury and can eventually result in the development of various neurodegenerative conditions such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). Hence, early detection of TBI can be beneficial for the outcome. Up until now the definitive diagnosis of TBI relies on the brain autopsy findings of the diseased person. Hence, there is need to identify a panel of biomarkers for detecting TBI that can detect the injury early, for taking timely measures to prevent future morbidity. This review aims to identify a panel of plasma neuro-biomarkers that can be used to screen TBI in adults. The markers are identified based on a predesigned rubric to check the biochemical origin, detectability, association with TBI and quantification sensitivity. The review will help the readers/researchers/clinicians to identify the complications at very early stage of disease progression.
Supernova-Driven Outflows in NGC 7552: A Comparison of H-alpha and UV Tracers
Creators: name: Wood, Corey M.
name: Tremonti, Christy A.
name: Calzetti, Daniela
name: Leitherer, Claus
name: Chisholm, John
name: Gallagher, John S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate the supernova-driven galactic wind of the barred spiral galaxy NGC 7552, using both ground-based optical nebular emission lines and far-ultraviolet absorption lines measured with the Hubble Space Telescope Cosmic Origins Spectrograph. We detect broad (~300 km/s) blueshifted (-40 km/s) optical emission lines associated with the galaxy's kpc-scale star-forming ring. The broad line kinematics and diagnostic line ratios suggest that the H-alpha emission comes from clouds of high density gas entrained in a turbulent outflow. We compare the H-alpha emission line profile to the UV absorption line profile measured along a coincident sight line and find significant differences. The maximum blueshift of the H-alpha-emitting gas is ~290 km/s, whereas the UV line profile extends to blueshifts upwards of 1000 km/s. The mass outflow rate estimated from the UV is roughly nine times greater than that estimated from H-alpha. We argue that the H-alpha emission traces a cluster-scale outflow of dense, low velocity gas at the base of the large-scale wind. We suggest that UV absorption line measurements are therefore more reliable tracers of warm gas in starburst-driven outflows.
description: 19 pages, 13 figures. Accepted for publication in Monthly Notices of the Royal Astronomical Society
What's wrong with the deficit debate?
Creators: name: Alexander, Don
Publisher: name: Vancouver Island University - Royal Roads University
Year: 1995
Subjects: subject: Canada--Politics and government
subject: Debts, Public--Canada

description: Unemployment insurance, welfare, social security, deficit, debt. Am I the only person in the country who is confused by the current debate on the social safety net and the related issue of public debt? Am I the only person who feels that no party to the debate can be entirely trusted, that everyone has their own axe to grind - whether it be the right, the left, the government, or the opposition? Though I don't claim to know the "truth" about these issues, I may be able to offer some clues as to what's wrong with the debate itself
description: This article was originally published as: Alexander, D. (1995). What’s wrong with the deficit debate? New City Magazine, 16(1), 52-53. New City Magazine, previously known as City Magazine, was a Canadian periodical dealing with housing and urban planning topics. The magazine ceased publication in Summer 1997.
description: Appeared in the CASE Study department of New City magazine as an editorial article.
description: https://viurrspace.ca/bitstream/handle/10613/5466/Alexander.NCM.Editorial.pdf?sequence=3
Platyschisma M'Coy 1844
Creators: name: Yoo, E. K.
Publisher: name: Zenodo
Year: 1994
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Euomphalina
Platyceratidae
Platyschisma

description: Platyschisma M'Coy, 1844 Australian Carboniferous species. Platyschisma lingua n.sp., from 'Rangari'; Platyschisma vitrea n.sp., from 'Marohn'. Remarks. The Early Permian species Platyschisma allandalensis Mitchell (1922) and the form referred to Platyschisma oculus Sowerby by de Koninck (1876) are large in size. The width of P. allandalensis is lO 5 mm. The original figures of P. allandalensis does not show the detail of the shell, and its exact locality is not known. Comparison of P. allandalensis with the type species, Platyschisma helicoides Sowerby, suggests that P. allandalensis is better referred to Keeneia of Etheridge (1902).
description: Published as part of Yoo, E. K., 1994, Early Carboniferous Gastropoda from the Tamworth Belt, New South Wales, Australia, pp. 63-120 in Records of the Australian Museum 46 (1) on page 74, DOI: 10.3853/j.0067-1975.46.1994.18, http://zenodo.org/record/4654599
description: {"references": ["Mitchell, J., 1922. A new gastropod (Fam. Euomphalidae) from the lower marine series of New South Wales. Linnean Society of New South Wales Proceedings 47: 278.", "Koninck, L. G. de, 1876. Recherches sur 1 es Fossiles Paleozoiques de da Nouvelle Galles du Sud (Australia). Mem. Soc. Roy. Sci. Liege. 2, 6. (Translated, 1898, as: Descriptions of the Palaeozoic fossils of New South Wales (Australia). Geological Survey of New South Wales (Palaeontology) 6: 1 - 294.", "Etheridge, R. Jr., 1902. A new Permo-Carboniferous genus (Keeneia). Records of the Australian Museum IV, 5: 195 - 200."]}
Тенденції та перспективи розвитку професійної освіти в контексті нових економічних викликів
Creators: name: Кучай, Олександр Володимирович
name: Ковальський, Дем`ян Олександрович
Publisher: name: Zenodo
Year: 2024
Subjects: професійна освіта, інноваційні технології, реформування, державно-приватне партнерство, цифровізація, розвиток

description: У статті проаналізовано основні тенденції та перспективи розвитку професійної освіти у контексті нових економічних викликів. Розглянуто вплив цифровізації та необхідність адаптації освітніх програм до змінюваних умов робочого середовища. Особливу увагу приділено розробці освітніх програм, що забезпечують практичне володіння компетенціями, затребуваними в цифровій економіці, включаючи обробку даних, кібербезпеку, та розробку робототехнічних систем.

Охарактеризовано важливість зеленої економіки та необхідність підготовки фахівців у сферах альтернативної енергетики та екологічного управління, акцентуючи на впровадженні курсів, які вивчають відновлювані джерела енергії та методи оцінки впливу на довкілля. Зясовано, як залучення студентів до реальних проєктів та співпраця з бізнесом може підвищити якість освіти та забезпечити випускників необхідними компетенціями для вирішення актуальних проблем.

Зазначено, що у зв’язку з триваючим військовим конфліктом, професійна освіта в Україні зіткнулася з викликами, що вимагають екстреної адаптації навчальних планів і методик до екстремальних умов. Нормативно-правові засади, що були реалізовані в умовах конфлікту, включають внутрішню академічну мобільність та можливість перенесення навчання в безпечніші регіони, забезпечуючи продовження освітнього процесу та зниження рівня безробіття серед молоді.

Визначено критичну роль професійної освіти в адаптації до демографічних змін, зокрема зростаючої потреби в медичних та соціальних послугах для старіючого населення. Обґрунтовано необхідність інтеграції практичних навчань з медичними та соціальними установами для підготовки фахівців у спеціалізованих областях, таких як геріатрія та паліативний догляд.

Сформовані висновки щодо необхідності постійного перегляду та оновлення навчальних програм, інтеграції нових технологій та наукових досягнень, а також впровадження передових методик навчання. Підкреслено значення міжнародної співпраці для підвищення якості освіти та відповідності до глобальних стандартів, а також важливість державно-приватного партнерства для адаптації освітніх систем до динамічних змін у робочому середовищі та ринку праці.
Substance Use and Resettled Refugees: Emerging Evidence and Implications for Practice
Creators: name: White, Kelsey
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Substance use among refugees is a neglected area of public health and service delivery, despite far-reaching health and social consequences for individuals, families, and communities. Emerging evidence suggests that refugees may experience increased vulnerability to substance use due to the unique risk factors they face throughout the migration journey. The UNC Refugee Mental Health and Wellness Initiative (based in Chapel Hill, North Carolina) has recognized substance use as a concern among some local refugee groups; however, a recent community needs assessment noted that a disconnect exists between refugees and local providers in their perceptions of substance use as a community concern. This project seeks to raise provider awareness by developing a learning module about substance use in refugee populations. Intended for public health practitioners and service providers who work with resettled refugees, the module outlines risk factors that may contribute to substance use among refugees, models proposed to explain substance use onset in migrant populations, and implications for practice at individual, community, and systems levels.
Assessment of Rental Construction Equipment Utilization case of Some Selected Construction Companies in Addis Ababa
Creators: name: Hadgu Tsehaye Meshesha
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Contractors, Rental Equipments, Equipment Availability and Equipment utilization

description: Construction industry has paramount importance in accelerating the development of infrastructural assets
 of nations worldwide; irrespective of their class category of being developed, developing or
 underdeveloped countries. However, its level of impact in all aspects of one’s overall socio-economic
 development becomes highly critical for those nations that are currently categorized as developing or
 underdeveloped; including Ethiopia. The sustainability and competitiveness of the construction projects
 has resulted through effective and efficient accomplishment of construction projects in a due time.
 In this study, the availability and utilization of construction equipments are the most critical priority of
 construction projects The two construction contractors (Aser construction plc and Yotek construction plc)
 have been considered for demonstrating the availability, utilization of equipment and the assessment of
 rental equipment as compare to own equipments. To accomplish this study, both primary and secondary
 data have been collected and analyzed. An intensive literature review has yield relevant lessons regarding
 to the assessment of utilization of rental equipment for contractors in construction projects. Detail data
 have been retrieved from six different projects in the two case construction companies (Aser and Yotek
 construction plc). Face to face interview and phone interviews have also been conducted.
 This study has focused on comparative analysis between own equipments and rental equipments on their
 availability and utilization. The two construction companies (Aser construction plc and Yotek
 construction plc) have used a total of 324 construction equipments to accomplish the six projects out of
 which 69 are their own and the remaining 255 construction equipments are rental. This indicates that
 those two construction companies have used very high rental construction equipments than their own
 construction equipments. On average the utilization rate of own equipments in six projects is 86.29% and
 for rental equipments the utilization is 93.68 percent. This indicate that rental equipments for those six
 projects have higher utilization than the own construction equipments. Therefore, the rental construction
 equipments are more utilized than the own construction equipment in these projects.
Theory of bound-electron g factor in highly charged ions
Creators: name: Shabaev, V. M.
name: Glazov, D. A.
name: Plunien, G.
name: Volotka, A. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The paper presents the current status of the theory of bound-electron g factor in highly charged ions. The calculations of the relativistic, QED, nuclear recoil, nuclear structure, and interelectronic-interaction corrections to the g factor are reviewed. Special attention is paid to tests of QED effects at strong coupling regime and determinations of the fundamental constants.
description: 20 pages, 7 figures
Inclusive Emergency Planning... What Do Access and Functional Needs And Registries Have To Do With It?
Creators: name: Schroeder, Jennifer
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The Durham County Services for Access and Functional Emergencies (DCSAFE) committee was formed by the Durham County Public Health Department to collaborate with community stakeholders to identify access and functional needs populations within Durham County. The mission of DCSAFE is to work to reduce injury and disease within the access and functional needs populations in Durham County through organized and interdisciplinary efforts. DCSAFE is currently mapping out their strategic plan and is interested in research around access and functional needs registries. The purpose of this paper is to assist the DCSAFE committee and the Durham County Health Department in identifying and documenting the current legislation, literature, examples and challenges in regards to establishing and implementing an access and functional needs registry.
A computational study of possible mechanisms of singlet oxygen generation in miniSOG photoactive protein
Creators: name: Giudetti, Goran
name: Blinova, Anastasia R.
name: Grigorenko, Bella L.
name: Krylov, Anna I.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: We report high-level electronic structure calculations of electronic states in the miniSOG (for mini Singlet Oxygen Generator) photoactive protein designed to produce singlet oxygen upon light exposure. We consider a model system with a riboflavin (RF) chromophore. To better understand the photosensitisation process, we compute relevant electronic states of the combined oxygen-chromophore system and their couplings. The calculations suggest that singlet oxygen can be produced both by intersystem crossing, via a triplet state of the RF(T1)×O2(3Σg−) character as well as by triplet excitation energy transfer via a singlet state of the same character. The calculations also suggest a pathway for the production of the triplet state of the chromophore via internal conversion facilitated by oxygen. Our results provide concrete support to previously hypothesised scenarios.
Subthermal switching with nanomechanical relays
Creators: name: Unluer, Dincer
name: Ghosh, Avik W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present a physical model for electronic switching in cantilever based nano-electro-mechanical field effect transistors, focusing on the steepness of its switching curve. We find that the subthreshold swing of the voltage transfer characteristic is governed by two separate considerations - the ability of the charges to correlate together through dipolar interactions and amplify the active torque, versus the active pull-in forces that drive an abrupt phase transition and close the air gap between the tip of the cantilever and the drain. For small sized relays, dipolar and short-range Van Der Waals 'sticking' forces dominate, while for longer cantilevers the capacitive energy acquires a major role. The individual pull-in and pull-out phases demonstrate a remarkably low subthreshold swing driven by the capacitive forces, sharpened further by dipolar correlation. The sharp switching, however, comes at the expense of strong hysteresis as the metastable and stable states interchange along the forward and reverse phases of the voltage scan.
description: 8 pages, 8 figures
Statistical Analysis of Calcium-Imaged Population Activity
Creators: name: Koh, Tze Hui
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: classificationCode: 90399
subject: Biomedical Engineering not elsewhere classified

description: Calcium imaging has been widely adopted for its ability to record from large populations of labelled cells within the brain. Given that we know neurons work together in any task, we can study how populations of neurons covary with each other. Such statistical studies of population activity have been particularly useful in electrophysiology studies in helping our understanding about neural circuit mechanisms, and these analysis tools are only just beginning to be used in calcium imaging studies. The focus of this thesis is to provide a foundation for the statistical analysis of calcium imaged recordings of large populations of cells. In the first part of this thesis, we focus on population analysis techniques traditionally used on electrophysiological recordings, and ask the question of whether these techniques are appropriate for calcium imaged recordings of neuronal populations, and how they may be applied. In this process, we also developed a simultaneous dimensionality reduction and deconvolution method, termed Calcium Imaging Linear Dynamical System (CILDS). We found that when performing dimensionality reduction, there is benefit in leveraging population statistics to perform deconvolution for dimensionality reduction, as done in CILDS. In the second part of this thesis, we evaluated these different dimensionality reduction methods in calcium-imaged recordings from the dorsal raphe nucleus in larval zebrafish and V1 in mouse. We found that despite the different animal models and brain areas, CILDS outperformed other approaches towards dimensionality reduction on calcium-imaged neuronal populations. CILDS was better able to peer through the calcium decay and apply the appropriate degree of temporal smoothing to the latent variables. With our understanding of population analysis techniques on calcium imaged recordings of neurons, we were well positioned to begin the last part of this thesis, which is the exploratory analysis of glial and neuronal population interaction
Theory and Evidence of the Effects of Psychosocial Well-Being in Collaboration
Creators: name: Diabes, Matthew
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: Organizational Behavioral Psychology

description: Few aspects of life are more important to human experience than psychological health. Individuals experience the world through their own, unique sense-making processes, and so reality, from a subjective point of view, very much is the private, psychological result of those internal processes. How healthy people are, psychologically and socially, constitutes a primary lens through which they make sense of their life experiences. It determines generalized perceptions about the self and the world—from the worth of one’s own life, to the level of threat out in the world, to the trustworthiness of other people. This dissertation expands our understanding of the implications of psychological and social well-being to one more frontier: collaboration. In three chapters, I develop theory and provide evidence of the effects of psychosocial well-being in fostering effective collaboration. In Chapter 1, I propose an integrated definition and theoretical structure of psychosocial well-being, providing a common future direction for extant disparate perspectives. I define psychosocial well-being as an individual’s level of psychological health, evident by how they feel about themselves and their life in terms of their experiences of happiness and fulfillment in life. In addition, I develop the Effects of Psychosocial Well-Being in Collaboration (EPiC) model, which integrates theory from multiple disciplines to describe the process through which an individual’s psychosocial well-being shapes both their own and their fellow collaborators’ experiences, contributions, and effectiveness in collaboration. I employ the EPiC model to advance several propositions and describe the model’s implications for organizational collaboration to guide future research and practice. In Chapters 2 and 3, I provide empirical evidence that supports the theoretical structure of psychosocial well-being and the EPiC model proposed in Chapter 1. The studies leverage the complementary strengths of multiple methods, spanning laboratory, academic, and high-stakes field settings (i.e., emergency healthcare). The empirical work of Chapters 2 and 3 provide evidence, confirmatory of the EPiC model and its implications, that individuals’ psychosocial well-being positively influences the trust they have for their collaborators, their collaborative contributions, and ultimately, the satisfaction and performance of their teams.
Human Capital Investment and Employment in Iran: The Importance of Urban-Rural Distinctions
Creators: name: Izadi, Gissa
Publisher: name: University of Westminster
Year: 2018

description: This thesis explores factors related to private investment in education in Iran. All of the three empirical chapters pay particular attention to the very different findings obtained when considering urban versus rural contexts and the implications this has for gender in Iran. For the first two empirical chapters, we use data from the Household Expenditures and Income Survey (HEIS), while for the last chapter, we employ data from the Labour Force Survey (LFS). Household/parental educational expenditure on children is one factor related to private investment in education. We study determinants of household/parental educational expenditure on children, and results in this chapter indicate two interesting findings; firstly, richer parents, especially in urban areas, spend more money on their children's education, which suggest possible existence of intergenerational mobility. Secondly, in rural areas maternal education is not significantly related to determining the decision to spend on education, the amount spent, and the proportion of household expenditure allocated, which suggest possible existence of gender discrimination in rural areas. Chapter 5 explores both naïve and causal returns to education in terms of wages by using both OLS and Instrumental Variable techniques. Our OLS results provide strong evidence for non-linearity, and higher returns to schooling for women, and suggest that returns to education are similar between urban and rural areas. Our IV estimates are higher than OLS estimates, and imply that returns to education are higher for urban than rural areas, and for women than men. Finally, we examine job mismatch in the Iranian labour market in Chapter 6; particularly determinants of under/over employment. Most of our findings are consistent with the existing studies of under/over employment. However, notably we find that marriage and education have different implications for men and women, and more educated women suffer from higher underemployment, while the opposite is true for men. We also find that single and divorced women are suffering from high underemployment, while marriage is not significantly related to men’s probability of job-mismatch. Overall, studying various factors related to private investment in human capital in Iran suggests the possible existence of increasing intergenerational mobility, but also discrimination, against women within the Iranian labour market.
The formation history of massive cluster galaxies as revealed by CARLA
Creators: name: Cooke, E. A.
name: Hatch, N. A.
name: Rettura, A.
name: Wylezalek, D.
name: Galametz, A.
name: Stern, D.
name: Brodwin, M.
name: Muldrew, S. I.
name: Almaini, O.
name: Conselice, C. J.
name: Eisenhardt, P. R.
name: Hartley, W. G.
name: Jarvis, M.
name: Seymour, N.
name: Stanford, S. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We use a sample of 37 of the densest clusters and protoclusters across $1.3 \le z \le 3.2$ from the Clusters Around Radio-Loud AGN (CARLA) survey to study the formation of massive cluster galaxies. We use optical $i'$-band and infrared 3.6$μ$m and 4.5$μ$m images to statistically select sources within these protoclusters and measure their median observed colours; $\langle i'-[3.6] \rangle$. We find the abundance of massive galaxies within the protoclusters increases with decreasing redshift, suggesting these objects may form an evolutionary sequence, with the lower redshift clusters in the sample having similar properties to the descendants of the high redshift protoclusters. We find that the protocluster galaxies have an approximately unevolving observed-frame $i'-[3.6]$ colour across the examined redshift range. We compare the evolution of the $\langle i'-[3.6] \rangle$ colour of massive cluster galaxies with simplistic galaxy formation models. Taking the full cluster population into account, we show that the formation of stars within the majority of massive cluster galaxies occurs over at least 2Gyr, and peaks at $z \sim 2$-3. From the median $i'-[3.6]$ colours we cannot determine the star formation histories of individual galaxies, but their star formation must have been rapidly terminated to produce the observed red colours. Finally, we show that massive galaxies at $z>2$ must have assembled within 0.5Gyr of them forming a significant fraction of their stars. This means that few massive galaxies in $z>2$ protoclusters could have formed via dry mergers.
description: Accepted for publication in MNRAS. 20 pages including 13 figures & 2 appendices