cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Winning Solution to the IEEE CIG 2017 Game Data Mining Competition
Creators: name: Guitart, Anna
name: Chen, Pei Pei
name: Periáñez, África
Publisher: name: arXiv
Year: 2019
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Machine learning competitions such as those organized by Kaggle or KDD represent a useful benchmark for data science research. In this work, we present our winning solution to the Game Data Mining competition hosted at the 2017 IEEE Conference on Computational Intelligence and Games (CIG 2017). The contest consisted of two tracks, and participants (more than 250, belonging to both industry and academia) were to predict which players would stop playing the game, as well as their remaining lifetime. The data were provided by a major worldwide video game company, NCSoft, and came from their successful massively multiplayer online game Blade and Soul. Here, we describe the long short-term memory approach and conditional inference survival ensemble model that made us win both tracks of the contest, as well as the validation procedure that we followed in order to prevent overfitting. In particular, choosing a survival method able to deal with censored data was crucial to accurately predict the moment in which each player would leave the game, as censoring is inherent in churn. The selected models proved to be robust against evolving conditions---since there was a change in the business model of the game (from subscription-based to free-to-play) between the two sample datasets provided---and efficient in terms of time cost. Thanks to these features and also to their a ability to scale to large datasets, our models could be readily implemented in real business settings.
Conformational transitions of heteropolymers in dilute solutions
Creators: name: Timoshenko, E. G.
name: Kuznetsov, Yu. A.
name: Dawson, K. A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantitative Biology (q-bio)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: In this paper we extend the Gaussian self-consistent method to permit study of the equilibrium and kinetics of conformational transitions for heteropolymers with any given primary sequence. The kinetic equations earlier derived by us are transformed to a form containing only the mean squared distances between pairs of monomers. These equations are further expressed in terms of instantaneous gradients of the variational free energy. The method allowed us to study exhaustively the stability and conformational structure of some periodic and random aperiodic sequences. A typical phase diagram of a fairly long amphiphilic heteropolymer chain is found to contain phases of the extended coil, the homogeneous globule, the micro-phase separated globule, and a large number of frustrated states, which result in conformational phases of the random coil and the frozen globule. We have also found that for a certain class of sequences the frustrated phases are suppressed. The kinetics of folding from the extended coil to the globule proceeds through non-equilibrium states possessing locally compacted, but partially misfolded and frustrated, structure. This results in a rather complicated multistep kinetic process typical of glassy systems.
description: 15 pages, RevTeX, 20 ps figures, accepted for publication in Phys. Rev. E
Eristena straminealis Hampson 1903
Creators: name: Singh, Navneet
name: Ranjan, Rahul
name: Talukdar, Avishek
name: Joshi, Rahul
name: Kirti, Jagbir Singh
name: Chandra, Kailash
name: Mally, Richard
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Crambidae
Eristena
Eristena straminealis

description: 36. Eristena straminealis Hampson, 1903b: 209
Type locality: Sikhim [Sikkim], 7000 feet
Distribution. Indian records: Sikkim (Hampson 1903b, Klima 1937). Global records: unknown.
  Genus Goniopalpia Hampson, 1903b: 19
 Type species: Goniopalpia delicatalis Hampson, 1903b, by monotypy
description: Published as part of Singh, Navneet, Ranjan, Rahul, Talukdar, Avishek, Joshi, Rahul, Kirti, Jagbir Singh, Chandra, Kailash & Mally, Richard, 2022, A catalogue of Indian Pyraloidea (Lepidoptera), pp. 1-423 in Zootaxa 5197 (1) on page 148, DOI: 10.11646/zootaxa.5197.1.1, http://zenodo.org/record/7252292
New chemical constituents from the fruits of Tetradium ruticarpum
Creators: name: Xin, Xiulan
name: Shao, Bo
name: Li, Ye
name: Liu, Shasha
name: Li, Dawei
name: Wang, Chao
name: Chen, Liang
name: Jin, Lihua
name: Ma, Xiaochi
name: Wu, Guoyu
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Two new γ-lactone derivatives, evodinoids A (1) and B (2), along with a new essential oil (3) were isolated from the nearly ripe fruits of Tetradium ruticarpum. The structures of these isolations were determined by 1D and 2D NMR, HR-ESI-MS and ECD data analysis. In addition, the cytotoxic effect of compounds 1−3 was evaluated against human cancer cells A498, A549, HepG-2, MCF-7 and SHSY-5Y, which displayed no significant cytotoxicity (IC50 > 100 μM).
Search for the Standard Model Higgs boson at LEP in the year 2000
Creators: name: The DELPHI Collaboration
name: Abreu, P.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Searches for the Standard Model Higgs boson have been performed in the data collected by the DELPHI experiment at LEP in the year 2000 at centre-of-mass energies between 200 and 209 GeV corresponding to a total integrated luminosity of 224 pb^{-1}. No evidence for a Higgs signal is observed in the kinematically accessible mass range, and a 95% CL lower mass limit of 114.3 GeV/c^2 is set, to be compared with an expected median limit of 113.5 GeV/c^2 for these data.
description: 19 pages, 9 figures
Covariant two point function for minimally coupled scalar field in de Sitter space-time
Creators: name: Takook, Mohammad Vahid
Publisher: name: arXiv
Year: 2000
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In a recent paper [1], it has been shown that negative norm states are indispensable for a fully covariant quantization of the minimally coupled scalar field in de Sitter space. Their presence, while leaving unchanged the physical content of the theory, offers an automatic and covariant renormalization of the vacuum energy divergence. This paper is a completion of our previous work. An explicit construction of the covariant two-point function of the ``massless'' minimally coupled scalar field in de Sitter space is given, which is free of any infrared divergence. The associated Schwinger commutator function and retarded Green's function are calculated in a fully gauge invariant way, which also means coordinate independent.
description: 7 pages, LaTex; some details added
TRITIUM - A Real-Time Tritium Monitor System for Water Quality Surveillance
Creators: name: Azevedo, C. D. R.
name: Baeza, A.
name: Bras, M.
name: Camara, T.
name: Cerna, C.
name: Chauveau, E.
name: Gil, J. M.
name: Corbacho, J. A.
name: Delgado, V.
name: Díaz, J.
name: Domange, J.
name: Marquet, C.
name: Martínez-Roig, M.
name: Moreno, A.
name: Piquemal, F.
name: Rodríguez, A.
name: Rodríguez, J.
name: Roldan, C.
name: Veloso, J. F. C. A.
name: Yahlali, N.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: In this work the development results of the TRITIUM project is presented. The main objective of the project is the construction of a near real-time monitor for low activity tritium in water, aimed at in-situ surveillance and radiological protection of river water in the vicinity of nuclear power plants. The European Council Directive 2013/51/Euratom requires that the maximum level of tritium in water for human consumption to be lower than 100 Bq/L. Tritium levels in the cooling water of nuclear power plants in normal operation are much higher than the levels caused by the natural and cosmogenic components, and may easily surmount the limit required by the Directive. The current liquid-scintillation measuring systems in environmental radioactivity laboratories are sensitive to such low levels, but they are not suitable for real-time monitoring. Moreover, there is no currently available device with enough sensitivity and monitoring capabilities that could be used for surveillance of the cooling water of nuclear power plants. A detector system based on scintillation fibers read out by photomultiplier tubes (PMTs) or silicon photomultiplier (SiPM) arrays is under development for in-water tritium measurement. This detector will be installed in the vicinity of Almaraz nuclear power plant (Spain) in Spring 2019. An overview of the project development and the results of first prototypes are presented.
description: 6 pages, 11 figures, IEEE NSS-MIC Conf Record 2018
title: Semantics-Based Exploratory Search on Manufacturing Knowledge
Creators: name: Haller, Kevin
Publisher: name: TU Wien
Year: 2024
Subjects: subject: Knowledge represenation
subject: Semantic Search

description: Knowledge graphs have been identified within the manufacturing industry as a suitable technology for integrating multidisciplinary knowledge from heterogeneous data sources. Effectively reusing this knowledge can enhance decision-making processes, and thereby fos- tering a competitive edge. However, there has been limited attention given in production research to the active human involvement in exploring these manufacturing knowledge graphs. In this context, exploratory search systems present a promising solution to encourage such engagement. Nevertheless, the majority of exploratory search systems are designed for general knowl- edge graphs where common knowledge suffices. Within the multifaceted and complex landscape of manufacturing, it is crucial to focus more closely on specific exploratory search features. Drawing from interviews with domain experts, this thesis highlights three distinct features that boost the efficacy of exploratory search for manufacturing environments. These include the system’s ability to tailor itself to numerous engineering perspectives, the availability of transparent provenance information that notably assists engineers in their investigative work, and the need for comprehending as well as navigating complex and deep hierarchical structures. An exploratory search system (ESS) has been designed, informed by an examination of common interface paradigms for generic exploratory search systems, coupled with an exploratory analysis of paradigms equipped to meet the identified requirements for the manufacturing domain. This system encompasses a rendering engine that supports an adaptive user interface, enabling a multifaceted configuration of visualizations and the underlying search algorithms. To address the need for provenance visibility, the system is structured to disseminate named graph information pertinent to each statement to the relevant UI components. A simple tree view was employed to overcome the challenge of navigating through hierarchical structures. This ESS prototype was evaluated on a small scale with five participants for the pilot factory use case. The initial assessment of the ESS demonstrated its value for users executing exploratory search tasks in the domain of collaborative robotics. Potential areas for enhancement were identified, however. Users perceived the tree view design as not useful, and they frequently opted for managing multiple browser tabs over utilizing the memorization feature. Despite these potential areas for improvement, users were overall successful in achieving their search objectives.
Oligostigma ustalis Walker 1866
Creators: name: Singh, Navneet
name: Ranjan, Rahul
name: Talukdar, Avishek
name: Joshi, Rahul
name: Kirti, Jagbir Singh
name: Chandra, Kailash
name: Mally, Richard
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Crambidae
Oligostigma
Oligostigma ustalis

description: 50. Oligostigma ustalis Walker, 1866a: 1529
Type locality: Indonesia, Java
 = Cymoriza fascialis Warren, 1896c: 223
Type locality: Khasias [Khasi Hills, Meghalaya]
 Distribution. Indian records: Khasis (Warren 1896c), Himalaya, Dharamshala, Kulu, Sikkim (Klima 1937), Uttarakhand (Pathania et al. 2021b). Global records: Java (Hampson 1896b), Java, Brit. Neu-Guinea [Papua New Guinea] (Klima 1937).
  Genus Opisthedeicta Warren, 1890: 478
 Type species: Oligostigma poritialis Walker, 1859a, by original designation
description: Published as part of Singh, Navneet, Ranjan, Rahul, Talukdar, Avishek, Joshi, Rahul, Kirti, Jagbir Singh, Chandra, Kailash & Mally, Richard, 2022, A catalogue of Indian Pyraloidea (Lepidoptera), pp. 1-423 in Zootaxa 5197 (1) on page 151, DOI: 10.11646/zootaxa.5197.1.1, http://zenodo.org/record/7252292
Blinded potency comparison of transthyretin kinetic stabilisers by subunit exchange in human plasma
Creators: name: Nelson, Luke T.
name: Paxman, Ryan J.
name: Xu, Jin
name: Webb, Bill
name: Powers, Evan T.
name: Kelly, Jeffery W.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Transthyretin (TTR) tetramer dissociation is rate limiting for aggregation and subunit exchange. Slowing of TTR tetramer dissociation via kinetic stabiliser binding slows cardiomyopathy progression. Quadruplicate subunit exchange comparisons of the drug candidate AG10, and the drugs tolcapone, diflunisal, and tafamidis were carried out at 1, 5, 10, 20 and 30 µM concentrations in 4 distinct pooled wild type TTR (TTRwt) human plasma samples. These experiments reveal that the concentration dependence of the efficacy of each compound at inhibiting TTR dissociation was primarily determined by the ratio between the stabiliser’s dissociation constants from TTR and albumin, which competes with TTR to bind kinetic stabilisers. The best stabilisers, tafamidis (80 mg QD), AG10 (800 mg BID), and tolcapone (3 x 100 mg over 12 h), exhibit very similar kinetic stabilisation at the plasma concentrations resulting from these doses. At a 10 µM plasma concentration, AG10 is slightly more potent as a kinetic stabiliser vs. tolcapone and tafamidis (which are similar), which are substantially more potent than diflunisal. Dissociation of TTR can be limited to 10% of its normal rate at concentrations of 5.7 µM AG10, 10.3 µM tolcapone, 12.0 µM tafamidis, and 188 µM diflunisal. The potency similarities revealed by our study suggest that differences in safety, adsorption and metabolism, pharmacokinetics, and tissue distribution become important for kinetic stabiliser clinical use decisions.
e-h Coherence and Charging Effects in Ultrasmall Metallic Grains
Creators: name: Drewes, S.
name: Renn, S. R.
name: Guinea, F.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We consider a model for electron tunneling between a pair of ultrasmall metallic grains. Under appropriate circumstances, non-equilibrium final state effects can strongly enhance tunneling and produce electron-hole coherence between the grains. The model displays a quantum phase transition between a Coulomb blockaded state to a coherent state exhibiting subohmic tunneling conductance. The critical state of the junction exhibits a temperature independent resistance of order $h/e^2$. Finally we discuss the possible relevance to granular materials and quantum dots. In particular, similarities between the quantum transition in our model and the metal-insulator transition in granular wires observed by Herzog et al. are described in detail.
description: 5 pages, 4 figures
The effects of invasive epibionts on crab-mussel communities: a theoretical approach to understand mussel population decline
Creators: name: Lyu, Jingjing
name: Auker, Linda A.
name: Priyadarshi, Anupam
name: Parshad, Rana D.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: Blue mussels (Mytilus edulis) are an important keystone species that have been declining in the Gulf of Maine. This could be attributed to a variety of complex factors such as indirect effects due to invasion by epibionts, which remains unexplored mathematically. Based on classical optimal foraging theory and anti-fouling defense mechanisms of mussels, we derive an ODE model for crab-mussel interactions in the presence of an invasive epibiont, Didemnum vexillum. The dynamical analysis leads to results on stability, global boundedness and bifurcations of the model. Next, via optimal control methods we predict various ecological outcomes. Our results have key implications for preserving mussel populations in the advent of invasion by non-native epibionts. In particular they help us understand the changing dynamics of local predator-prey communities, due to indirect effects that epibionts confer.
description: 33 pages, 24 figures
On the extension of the concept of Thin Shells to The Einstein-Cartan Theory
Creators: name: Bressange, Georges F.
Publisher: name: arXiv
Year: 2000
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This paper develops a theory of thin shells within the context of the Einstein-Cartan theory by extending the known formalism of general relativity. In order to perform such an extension, we require the general non symmetric stress-energy tensor to be conserved leading, as Cartan pointed out himself, to a strong constraint relating curvature and torsion of spacetime. When we restrict ourselves to the class of space-times satisfying this constraint, we are able to properly describe thin shells and derive the general expression of surface stress-energy tensor both in its four-dimensional and in its three-dimensional intrinsic form. We finally derive a general family of static solutions of the Einstein-Cartan theory exhibiting a natural family of null hypersurfaces and use it to apply our formalism to the construction of a null shell of matter.
description: Latex, 21 pages, 1 combined Latex/Postscript figure; Accepted for publication in Classical and Quantum Gravity
Is interleukin-2 an optimal marker for diagnosing tuberculosis infection? A systematic review and meta-analysis
Creators: name: Qiu, Xia
name: Wang, Huiqing
name: Tang, Ying
name: Su, Xiaojuan
name: Ge, Long
name: Qu, Yi
name: Mu, Dezhi
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Computational Biology

description: Latent tuberculosis infection (LTBI) is a huge reservoir for the deadlier TB disease. Accurate identification of LTBI is a key strategy to eliminate TB. Therefore, a systematic review and meta-analysis approach was used to assess diagnostic potential of IL-2 for LTBI. PubMed, Web of Science, the Cochrane Library and Embase were searched. The pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), area under the summary receiver operating characteristic curve (AUROC) and hierarchical summary receiver operating characteristic curve (HSROC) were estimated by bivariate and HSROC models. Twenty-seven studies including 1404 participants and 1986 samples met the inclusion criteria. The pooled sensitivity, specificity, PLR, NLR, DOR and AUROC of IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls. For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR, DOR and AUROC of IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2. These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals.
Stress in a polymer brush
Creators: name: Manav, M.
name: Ponga, M.
name: Phani, A. Srikantha
Publisher: name: arXiv
Year: 2018
Subjects: subject: Applied Physics (physics.app-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We study the stress distribution in a polymer brush material over a range of graft densities using molecular dynamics (MD) simulations and theory. Flexible polymer chains are treated as beads connected by nonlinear springs governed by a modified finitely extensible nonlinear elastic (FENE) potential in MD simulations. Simulations confirmed the quartic variation of the normal stress parallel to the substrate, within the bulk of the brush, as predicted in our previous work, for low graft densities. However, in the high graft density regime, the Gaussian chain elasticity assumption is violated by finite extensibility effects (force-extension divergence) and the restriction to binary interaction among monomers is insufficient. This motivated us to extend a semi-analytical strong stretching mean field theory (SST) for polymer brushes, based on Langevin chains and a modified Carnahan-Starling equation of state to model monomer interactions. Our extended theory elucidates the stress and monomer density profiles obtained from MD simulations, as well as reproduces Gaussian chain results for small graft densities. A good agreement is observed between predictions of MD and Langevin chain SST for monomer density profile, end density profile and stress profile in high graft density regime, without fitting parameters (virial coefficients). Quantitative comparisons of MD results with various available theories suggest that excluded volume correlations may be important.
Double-Spin Asymmetry in the Cross Section for Exclusive rho^0 Production in Lepton-Proton Scattering
Creators: name: HERMES Collaboration
name: Airapetian, A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Evidence for a positive longitudinal double-spin asymmetry = 0.24 +-0.11 (stat) +-0.02 (syst) in the cross section for exclusive diffractive rho^0(770) vector meson production in polarised lepton-proton scattering was observed by the HERMES experiment. The longitudinally polarised 27.56 GeV HERA positron beam was scattered off a longitudinally polarised pure hydrogen gas target. The average invariant mass of the photon-proton system has a value of = 4.9 GeV, while the average negative squared four-momentum of the virtual photon is = 1.7 GeV^2. The ratio of the present result to the corresponding spin asymmetry in inclusive deep-inelastic scattering is in agreement with an early theoretical prediction based on the generalised vector meson dominance model.
description: 10 pages, 4 embedded figures, LaTeX
Constraint to chiral invariant masses of nucleons from GW170817 in an extended parity doublet model
Creators: name: Yamazaki, Takahiro
name: Harada, Masayasu
Publisher: name: arXiv
Year: 2019
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We construct nuclear matter based on an extended parity doublet model including four light nucleons $N(939)$, $N(1440)$, $N(1535)$, and $N(1650)$. We exclude some values of the chiral invariant masses by requiring the saturation properties of normal nuclear matter; saturation density, binding energy, incompressibility, and symmetry energy. We find further constraint to the chiral invariant masses from the tidal deformability determined by the observation of the gravitational waves from neutron star merger GW170817. Our result shows that the chiral invariant masses are larger than about $600\,$MeV. We also give some predictions on the symmetry energy and the slope parameters in the high density region, which will be measured in future experiments.
description: 12 pages, 15 figures
Identification of differentially expressed and methylated genes associated with rheumatoid arthritis based on network
Creators: name: Zhang, Di
name: Li, ZhaoFang
name: Zhang, RongQiang
name: Yang, XiaoLi
name: Zhang, DanDan
name: Li, Qiang
name: Wang, Chen
name: Yang, Xuena
name: Xiong, YongMin
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Rheumatoid arthritis (RA) is a multi-systemic inflammatory autoimmune disease involving peripheral joints, and the pathogenesis is not clear. Studies showed that DNA methylation and expression might also be involved in the pathogenesis of RA. This study integrated three expression profile datasets (GSE55235, GSE12021, and GSE55457) and one methylation profile dataset GSE111942 to elucidate the potential essential candidate genes and pathways in RA. Differentially expressed genes (DEGs) and differentially methylation genes (DMGs) were identified by R programming software, using Limma package and ChAMP package, respectively. DAVID performed gene Ontology (GO) and Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEGs. Functional annotation and construction of a protein–protein interaction (PPI) network and the Molecular Complex Detection Algorithm (MCODE) were analysed by STRING and Cystoscope, respectively. Then the connection analysis of DEGs and DMGs was carried out, and further to analyse the relationship between methylation and gene expression, aiming to screen out the potential genes. In this study, 288 DEGs and 228 DMGs were identified, and the majority of DEGs were up-regulated. Enrichment analysis represented that DEGs mainly involved immune response and participated in the Cytokine–cytokine receptor interaction signal pathway. 282 nodes were identified from DEGs PPI network and MCODE, filtering the most significant 2 modules, 23 core node genes were identified and most of them are involved in the T cell receptor signalling pathway and chemokine-mediated signalling pathway. Cross-analysis revealed 4 genes [KNTC1 (cg 01277763), LRRC8D (cg 07600884), DHRS9 (cg 05961700), and UCP2 (cg 05205664)] that exhibited differential expression and methylation in RA simultaneously. Therefore, the four genes could be used as the target for RA.
Additional file 1: of Cross-cultural adaptation and psychometric properties of the MMSE and MoCA questionnaires in Tanzanian Swahili for a traumatic brain injury population
Creators: name: Joao Vissoci
name: Oliveira, Leonardo
name: Temitope Gafaar
name: Haglund, Michael
name: Mvungi, Mark
name: Mmbaga, Blandina
name: Staton, Catherine
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Tanzanian Swahili version of MMSE. (DOCX 25 kb)
Additional file 1: of The burden of health conditions for middle-aged and older adults in the United States: disability-adjusted life years
Creators: name: McGrath, Ryan
name: Soham Snih
name: Markides, Kyriakos
name: Orman Hall
name: Peterson, Mark
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Table S1. Example Interviewer Questions for Each Health Condition (DOCX 13 kb)
Effective dynamics of a conditioned generalized linear Glauber model
Creators: name: Kaviani, Sara
name: Jafarpour, Farhad H.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: In order to study the stochastic Markov processes conditioned on a specific value of a time-integrated observable, the concept of ensembles of trajectories has been recently used extensively. In this paper, we consider a generic reaction-diffusion process consisting of classical particles with nearest-neighbor interactions on a one-dimensional lattice with periodic boundary conditions. By introducing a time-integrated current as a physical observable, we have found certain constraints on the microscopic transition rates of the process under which the effective process contains local interactions; however, with rescaled transition rates comparing to the original process. A generalization of the linear Glauber model is then introduced and studied in detail as an example. Associated effective dynamics of this model is investigated and constants of motion are obtained.
description: 11 pages, 5 figures, Published 27 July 2018
Zero-phonon lines in the spectra of dysprosium atoms in superfluid helium
Creators: name: Moroshkin, P.
name: Kono, K.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present an experimental study of a zero-phonon line (ZPL) in the absorption spectrum of Dy atoms solvated in superfluid He. The dopants reside in nanometer-sized spherical cavities known as atomic bubbles. We observe a temperature-dependent broadening of ZPL in the absorption spectrum. The effect is attributed to the scattering of thermal phonons on the atomic bubble that leads to the dephasing of the Dy transition dipole. The extrapolated ZPL intrinsic spectral width at zero temperature is 2300 times larger than the natural linewidth in a free atom. This can be assigned to a fast radiationless quenching of the upper state of the studied transition.
Additional file 1 of Genome variation in tick infestation and cryptic divergence in Tunisian indigenous sheep
Creators: name: Ahbara, Abulgasim M.
name: Khbou, Médiha Khamassi
name: Rhomdhane, Rihab
name: Sassi, Limam
name: Gharbi, Mohamed
name: Haile, Aynalem
name: Rekik, Mourad
name: Rischkowsky, Barbara
name: Mwacharo, Joram M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1.
Regio- and stereoselective hydroxylation of testosterone by cytochrome P450 from Streptomyces griseus ATCC 13273
Creators: name: Zhu, Jinqian
name: Shen, Chen
name: Zhao, Wanli
name: Liu, Xiufeng
name: Liu, Jihua
name: Yu, Boyang
Publisher: name: Taylor & Francis
Year: 2020
Subjects: Biochemistry
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: 16α-Hydroxylated steroids are important precursors in the synthesis of high value steroidal drugs such as glucocorticoids in the pharmaceutical industry. In this study, an innovative biotechnological method based on enzymatic catalysis was presented for the high-efficient production of 16α-hydroxyl-testosterone. CYP154C, a cytochrome P450 from Streptomyces griseus ATCC 13273, was identified to carry out a one-step regio- and stereoselective hydroxylation of testosterone along with putidaredoxin reductase (PDR) and putidaredoxin (Pdx) as the redox partner. The Km and kcat values of CYP154C for testosterone were 23.40 ± 3.69 μM and 4.75 min−1, respectively. The catalytic efficiency (kcat/Km) for testosterone was 12.18 s−1·μM−1. Using a CYP154-based whole-cell system in E. coli BL21(DE3), high efficiency of hydroxylation of testosterone for production of 16α-hydroxyl-testosterone was achieved. The bioconversion rate of testosterone (50 mg/L) by the whole cell system came up to 75 ± 2.87% within 24 h. These results demonstrated the high potential of CYP154-based biocatalytic system for 16α-hydroxyl-testosterone production.
Characterization of a recombinant bile salt hydrolase (BSH) from Bifidobacterium bifidum for its glycine-conjugated bile salts specificity
Creators: name: Li, Chou
name: Ji, Qingzhi
name: He, Tongyao
name: Liu, Yingying
name: Ma, Yunqing
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Deconjugation of bile salts in vivo not only promotes the cholesterol metabolism of the host, but also provides cellular carbon, nitrogen and sulphur for some probiotics. In this study, the gene of BSH from Bifidobacterium bifidum (ATCC 29521) was amplified and expressed using glutathione S-transferase (GST) Gene Fusion System. The enzyme was purified in a mild conditions without denaturation and renaturation, and the molecular mass was estimated to be 35 kDa. The optimum pH for the enzyme catalysis was 5.5. The BSH enzyme was stable from 37 to 57 °C. In addition, this enzyme was completely inhibited by Cu2+, while many other metal ions only gave moderate inhibition. Hydrolysis efficiency of BSH was quantified in two ways: ninhydrin colouration method and high-performance liquid chromatography coupled with evaporative light scattering detector (HPLC-ELSD). The hydrolysis process was clearly observed through real-time picture monitoring. The activity of BSH on glycine-conjugated bile salts was better than on taurine-conjugated bile salts. The proportion of hydrolysis for both sodium glycochenodeoxycholate (GCDCA) and sodium glycoursodeoxycholate (GUDCA) were more than 90% in 60 min. However, the proportion of hydrolysis for sodium taurochenodeoxycholate (TCDCA) and sodium tauroursodeoxycholate (TUDCA) were only 68% and 43% at the same condition. The study of this paper provides a better choice for hydrolysis of glycine-conjugated bile salts.HighlightsThe specificity of BSH was high for glycine-conjugated bile salts.Hydrolysis process of bile acid was obtained through real-time picture monitoring.Hydrolysis efficiency of BSH was quantified in two ways: ninhydrin colouration method and HPLC-ELSD. The specificity of BSH was high for glycine-conjugated bile salts. Hydrolysis process of bile acid was obtained through real-time picture monitoring. Hydrolysis efficiency of BSH was quantified in two ways: ninhydrin colouration method and HPLC-ELSD.
Notes on the Sasaki metric
Creators: name: Albuquerque, Rui
Publisher: name: arXiv
Year: 2018
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 37C10, 53C21, 53D25

description: We survey on the geometry of the tangent bundle of a Riemannian manifold, endowed with the classical metric established by S. Sasaki 60 years ago. Following the results of Sasaki, we try to write and deduce them by different means. Questions of vector fields, mainly those arising from the base, are related as invariants of the classical metric, contact and Hermitian structures. Attention is given to the natural notion of extension or complete lift of a vector field, from the base to the tangent manifold. Few results are original, but finally new equations of the mirror map are considered.
description: To appear in Expositiones Mathematicae; 15 pages;
Paracymoriza aurantialis Swinhoe 1895
Creators: name: Singh, Navneet
name: Ranjan, Rahul
name: Talukdar, Avishek
name: Joshi, Rahul
name: Kirti, Jagbir Singh
name: Chandra, Kailash
name: Mally, Richard
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Crambidae
Paracymoriza
Paracymoriza aurantialis

description: 54. Paracymoriza aurantialis Swinhoe, 1895b: 304
Type Locality: India
 Distribution. Indian records: Khasis (Meghalaya) (Hampson 1896b, Klima 1937), India (You et al. 2003, Chen et al. 2007). Global records: South and East China (Klima 1937), China (Jiangxi, Fujian, Hainan, Guangxi), Nepal, Thailand, Malaysia, Indonesia (Chen et al. 2007).
description: Published as part of Singh, Navneet, Ranjan, Rahul, Talukdar, Avishek, Joshi, Rahul, Kirti, Jagbir Singh, Chandra, Kailash & Mally, Richard, 2022, A catalogue of Indian Pyraloidea (Lepidoptera), pp. 1-423 in Zootaxa 5197 (1) on page 152, DOI: 10.11646/zootaxa.5197.1.1, http://zenodo.org/record/7252292
D2.2 Implementations of methods adapted to enhanced human inputs
Creators: name: , Doukhan
name: , Francis
name: Harrando
name: , Huet
name: Kaseva
name: Kurimo
name: , Laaksonen
name: Lindh-Knuutila
name: , Lisena
name: Pehlivan Tort
name: Reboud
name: Rouhe
name: , Troncy
name: Virkkunen
Publisher: name: Zenodo
Year: 2020
Subjects: media content analysis
multimodal data analysis

description: This deliverable describes the second development iteration of the joint collection of libraries and tools for multimodal content analysis from AALTO, EURECOM, INA, Lingsoft, LLS and Limecraft. Based on the methods’ primary input domain, they have been grouped as visual (facial person recognition, facial gender classification and video description), auditory (speech and gender segmentation, speech recognition and speaker identification and diarisation) and multimodal (audio-enhanced captioning, visual–auditory gender classification, person re-identification and multimodal speech recognition) approaches in this report. Special attention has been on methods that combine different modalities and bring human knowledge as input to the learning system. As part of this deliverable, the existing open source components gathered into a joint software collection of tools and libraries have been updated and new components have been added. This deliverable also summarises in an appendix the dissemination activities related to the research work in MeMAD’s Work Package WP2 during its second year. Finally, the abstracts of five academic theses together with full texts of ten scientific publications appear at the end of the report. These appendices describe the technological advances related to the software components of MeMAD Task T2.2 in further detail.
Quantum reflection of massless neutrinos from a torsion-induced potential
Creators: name: Alimohammadi, M.
name: shariati, A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the context of the Einstein-Cartan-Dirac model, where the torsion of the space-time couples to the axial currents of the fermions, we study the effects of this quantum-gravitational interaction on a massless neutrino beam crossing through a medium with high number density of fermions at rest. We calculate the reflection amplitude and show that a specific fraction of the incident neutrinos reflects from this potential if the polarization of the medium is different from zero. We also discuss the order of magnitude of the fermionic number density in which this phenomenon is observable, in other theoretical contexts, for example the strong-gravity regime and the effective field theory approach.
description: 8 pages, LaTex
D2.3 Software and demonstration of human-like content description generation
Creators: name: , Doukhan
name: , Guo
name: Harrando
name: Kurimo
name: , Laaksonen
name: Lindgren
name: Lindh-Knuutila
name: , Lisena
name: Pehlivan Tort
name: Reboud
name: Rouhe
name: Troncy
name: , Virkkunen
Publisher: name: Zenodo
Year: 2020
Subjects: media content analysis
multimodal data analysis

description: This deliverable describes the last development iteration of the joint collection of libraries and tools for multimodal content analysis and description from AALTO, EURECOM, INA, Lingsoft, LLS and Limecraft. The methods generate unimodal descriptions of video contents in the aural and visual domains. These descriptions can be used as such and also combined to describe the contents in a multimodal fashion as enriched video captions. The ultimate goal of the development is to be able to generate human-like content descriptions, in which the persons, objects, actions and environments, both seen and heard, are described in a sophisticated way. In this deliverable, a number of improvements we have made in that direction are elaborated. We describe a small-scale dataset used in the experiments and demonstrate and evaluate various multimodal combinations of the unimodal inputs with that data. As part of this deliverable, the existing open source components gathered into a joint software collection of tools and libraries have been updated and new components have been added. Finally, the abstracts of academic theses together with full texts of scientific publications appear at the end of the report.
Near-infrared spectroscopy of the massive stellar population of W51: evidence for multi-seeded star formation
Creators: name: Bik, A.
name: Henning, Th.
name: Wu, S. -W.
name: Zhang, M.
name: Brandner, W.
name: Pasquali, A.
name: Stolte, A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The interplay between the formation of stars, stellar feedback and cloud properties strongly influences the star formation history of giant molecular clouds. The formation of massive stars leads to a variety of stellar clusters, ranging from low stellar density OB associations to dense, gravitationally bound starburst clusters. We aimed at identifying the massive stellar content and reconstructing the star formation history of the W51 giant molecular cloud. We performed near-infrared imaging and K-band spectroscopy of the massive stars in W51. We analyzed the stellar populations using colour-magnitude and colour-colour diagrams and compared the properties of the spectroscopically identified stars with stellar evolution models. We derived the ages of the different sub-clusters in W51 and, based on our spectroscopy derived an age for W51 of 3 Myrs or less. The age of the P Cygni star LS1 and the presence of two still forming proto-clusters suggests that the star formation history of W51 is more complex than a single burst. We did not find evidence for triggered star formation and we concluded that the star formation in W51 is multi seeded. We finally concluded that W51 is a OB association where different sub-clusters form over a time span of at least 3-5 Myrs.
description: 21 Pages, 9 figures, accepted for publication by Astronomy and Astrophysics
Statistical Theory of Finite Fermi-Systems Based on the Structure of Chaotic Eigenstates
Creators: name: Flambaum, V. V.
name: Izrailev, F. M.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Nuclear Theory (nucl-th)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The approach is developed for the description of isolated Fermi-systems with finite number of particles, such as complex atoms, nuclei, atomic clusters etc. It is based on statistical properties of chaotic excited states which are formed by the interaction between particles. New type of ``microcanonical'' partition function is introduced and expressed in terms of the average shape of eigenstates $F(E_k,E)$ where $E$ is the total energy of the system. This partition function plays the same role as the canonical expression $exp(-E^{(i)}/T)$ for open systems in thermal bath. The approach allows to calculate mean values and non-diagonal matrix elements of different operators. In particular, the following problems have been considered: distribution of occupation numbers and its relevance to the canonical and Fermi-Dirac distributions; criteria of equilibrium and thermalization; thermodynamical equation of state and the meaning of temperature, entropy and heat capacity, increase of effective temperature due to the interaction. The problems of spreading widths and shape of the eigenstates are also studied.
description: 17 pages in RevTex and 5 Postscript figures. Changes are RevTex format (instead of plain LaTeX), minor misprint corrections plus additional references. To appear in Phys. Rev. E
Secusio atrizonata Hampson 1910
Creators: name: Mbata, Keith J.
name: Prins, Jurate De
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Secusio
Secusio atrizonata

description: Secusio atrizonata Hampson, 1910c
COMMON NAME(S): Tiger Moth.
SYNONYM(S): None.
IUCN STATUS: Not Evaluated (NE).
DISTRIBUTION: Known only from Zambia (endemic species).
LOCALITY IN ZAMBIA: Type Locality is in Lofu Valley on Tanganyika Plateau in N. E. Rhodesia [now N. E. Zambia], Northern Province.
LARVAL HOSTPLANT(S): Unknown.
SOURCES: De Prins & De Prins 2022; Hampson 1910c.
description: Published as part of Mbata, Keith J. & Prins, Jurate De, 2023, Annotated checklist of moths of Zambia (Insecta: Lepidoptera), pp. 1-503 in Zootaxa 5354 (1) on page 290, DOI: 10.11646/zootaxa.5354.1.1, http://zenodo.org/record/10130434
Pressure Effect on the Spin Fluctuations in YMn$_2$ --Mn NQR Study--
Creators: name: Nishikido, K.
name: Thessieu, C.
name: Zheng, G-q.
name: Kitaoka, Y.
name: Asayama, K.
name: Hauser, R.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report the NQR study on the pressure-induced paramagnetic state in the antiferromagnetic (AF) intermetallic compound YMn$_2$ with the Néel temperature T_N=100 K at ambient pressure. From the $T$ variation of the nuclear spin-lattice relaxation rate, $^{55}(1/T_1)$ of $^{55}$Mn above the critical pressure of 4 kbar, the spin fluctuation feature is found to change below a temperature $T_{sf}$. At higher temperature than $T_{sf}$, the nuclear relaxation behavior is well described in terms of the self-consistent renomalized (SCR) spin fluctuation theory for nearly AF metals, whereas below $T_{sf}$ a deviation is significant and $1/T_1T$ exhibits a weak $T$ variation. It is pointed out that $T_{sf}$ coincides with the temperature below which a $T^{2}$ law in electrical resistivity is valid as expected for a Fermi liquid ground state. We proposed that these features are understood from the standpoint that the development of AF spin fluctuation remains in short-range associated with the singlet formation among Mn spins in each tetrahedron as suggested by the inelastic neutron experiments on $Y_{1-x}Sc_xMn_2$.
description: 8 pages, 3 figures