cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hierarchically hyperbolic spaces I: curve complexes for cubical groups
Creators: name: Behrstock, Jason
name: Hagen, Mark F.
name: Sisto, Alessandro
Publisher: name: arXiv
Year: 2014
Subjects: subject: Geometric Topology (math.GT)
subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: In the context of CAT(0) cubical groups, we develop an analogue of the theory of curve complexes and subsurface projections. The role of the subsurfaces is played by a collection of convex subcomplexes called a \emph{factor system}, and the role of the curve graph is played by the \emph{contact graph}. There are a number of close parallels between the contact graph and the curve graph, including hyperbolicity, acylindricity of the action, the existence of hierarchy paths, and a Masur--Minsky-style distance formula. We then define a \emph{hierarchically hyperbolic space}; the class of such spaces includes a wide class of cubical groups (including all virtually compact special groups) as well as mapping class groups and Teichmüller space with any of the standard metrics. We deduce a number of results about these spaces, all of which are new for cubical or mapping class groups, and most of which are new for both. We show that the quasi-Lipschitz image from a ball in a nilpotent Lie group into a hierarchically hyperbolic space lies close to a product of hierarchy geodesics. We also prove a rank theorem for hierarchically hyperbolic spaces; this generalizes results of Behrstock--Minsky, Eskin--Masur--Rafi, Hamenstädt, and Kleiner. We finally prove that each hierarchically hyperbolic group admits an acylindrical action on a hyperbolic space. This acylindricity result is new for cubical groups, in which case the hyperbolic space admitting the action is the contact graph; in the case of the mapping class group, this provides a new proof of a theorem of Bowditch.
description: To appear in "Geometry and Topology". This version incorporates the referee's comments
LUNANOVA KICK STAGE STUDY: AN OVERVIEW OF THE SYSTEM PROPULSION TRADEOFFS
Creators: name:  L. ORDONEZ VALLES
name:   U. APEL
name:   M. TAJMAR
name:   L. BLONDEL CANEPARI
name:   A. PASINI
name:   A. JASJUKEVICS
name:   M. WOLF
name:   J. CARUANA
name:   S. DUSSY
Publisher: name: Proceedings of  the 9th European Conference for Aerospace Sciences. Lille, France, 27 June - 1 July, 2022
Year: 2022
Subjects: FUTURE SPACE OPERATIONS

description: LUNANOVA KICK STAGE STUDY: AN OVERVIEW OF THE SYSTEM PROPULSION TRADEOFFS Livia Ordonez Valles (ArianeGroup) Arturs Jasjukevics (ArianeGroup) Marco Wolf (ArianeGroup) Jean-Noel Caruana (ESA) Stephane Dussy (ESA) In the last years, the boom of commercial space has shaken the space sector and plunged it into a new era. These new times come along not only with a whole new portfolio of missions and services but also with a new range of capabilities and logistics required to enable them. Moreover, space exploration is also facing new challenges every day, with some of the most exciting missions ahead. Space logistics and Lunar exploration are undoubtedly the next stop of this hectic journey. ArianeGroup, willing to embrace this new vision, is already working to serve these missions by enhancing the future European launcher capabilities. Under ESA Future Launcher Preparatory Programme (FLPP), several studies are being developed, and among them, the LunaNova kick stage is the one that this paper will take care of. Kick stages are in charge of providing last mile orbit delivery to one or multiple payloads. Apart from these general to-orbit services, LunaNova shall target to offer a whole set of novel in-orbit services such as communications relay or active debris removal. The system design shall rely on innovative technologies to lower production and operational costs while improving competitiveness and commercial appeal. Storable green propellants, new tank configurations and innovative pressurisation systems have already been identified as improved alternatives to the conventional approach. Under this perspective, this paper will firstly provide an overview of the system specifications. Then, it will focus on the performed tradeoffs related to the propulsion system, i.e. pressurisation system and propellant selection. A cost-oriented approach was applied together with specific key performance parameters for each tradeoff. In the case of electric pump feeding, an estimate of the different masses of the pressurisation system was carried out for the pressure fed and electric pump-fed options. From the propellant selection point of view, hydrogen peroxide was set as the baseline oxidiser, and different analyses were carried out to assess the impact of key factors such as density and mixture ratio. Finally, a comprehensive view of the challenges and opportunities that the implementation of these identified technologies can bring to the European space ecosystem will also be provided.
Children’s Environmental Health Faculty Champions Initiative: A Successful Model for Integrating Environmental Health into Pediatric Health Care
Creators: name: Slavin, Katie
name: Grubb, Kimberly
name: McCurdy, Leyla Erk
name: Roberts, James R.
name: Rogers, Bonnie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundPediatric medical and nursing education lack the environmental health content needed to properly prepare health care professionals to prevent, recognize, manage, and treat environmental exposure–related diseases. The need for improvements in health care professionals’ environmental health knowledge has been expressed by leading institutions. However, few studies have evaluated the effectiveness of programs that incorporate pediatric environmental health (PEH) into curricula and practice.ObjectiveWe evaluated the effectiveness of the National Environmental Education Foundation’s (NEEF) Children’s Environmental Health Faculty Champions Initiative, which is designed to build environmental health capacity among pediatric health care professionals.MethodsTwenty-eight pediatric health care professionals participated in a train-the-trainer workshop, in which they were educated to train other health care professionals in PEH and integrate identified PEH competencies into medical and nursing practice and curricula. We evaluated the program using a workshop evaluation tool, action plan, pre- and posttests, baseline and progress assessments, and telephone interviews.ResultsDuring the 12 months following the workshop, the faculty champions’ average pretest score of 52% was significantly elevated (p < 0.0001) to 65.5% on the first posttest and to 71.5% on the second posttest, showing an increase and retention of environmental health knowledge. Faculty champions trained 1,559 health care professionals in PEH, exceeding the goal of 280 health care professionals trained. Ninety percent of faculty champions reported that PEH had been integrated into the curricula at their institution.ConclusionThe initiative was highly effective in achieving its goal of building environmental health capacity among health care professionals. The faculty champions model is a successful method and can be replicated in other arenas.
Lukas Vischer, Lukas Schenker, Rudolf Dellsperger (Hg.), Ökumenische Kirchengeschichte der Schweiz
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 49 Nr. 7 (1995): Herder Korrespondenz, Band 49, Heft 7
Dietary Fat Alters Body Composition, Mammary Development, and Cytochrome P450 Induction after Maternal TCDD Exposure in DBA/2J Mice with Low-Responsive Aryl Hydrocarbon Receptors
Creators: name: Kuruvilla, Bittu S.
name: Threadgill, David W.
name: Birnbaum, Linda S.
name: Pomp, Daniel
name: La Merrill, Michele
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundIncreased fat intake is associated with obesity and may make obese individuals uniquely susceptible to the effects of lipophilic aryl hydrocarbon receptor (AHR) ligands.ObjectivesWe investigated the consequences of high-fat diet (HFD) and AHR ligands on body composition, mammary development, and hepatic P450 expression.MethodsPregnant C57BL/6J (B6) and DBA/2J (D2) dams, respectively expressing high- or low-responsive AHR, were dosed at mid-gestation with TCDD. At parturition, mice were placed on an HFD or a low-fat diet (LFD). Body fat of progeny was measured before dosing with 7,12-dimethylbenz[a]anthracene (DMBA). Fasting blood glucose was measured, and liver and mammary glands were analyzed.ResultsMaternal TCDD exposure resulted in reduced litter size in D2 mice and, on HFD, reduced postpartum survival in B6 mice. In D2 mice, HFD increased body mass and fat in off-spring, induced precocious mammary gland development, and increased AHR expression compared with mice given an LFD. Maternal TCDD exposure increased hepatic Cyp1a1 and Cyp1b1 expression in offspring on both diets, but DMBA depressed Cyp1b1 expression only in mice fed an HFD. In D2 progeny, TCDD exposure decreased mammary terminal end bud size, and DMBA exposure decreased the number of terminal end buds. Only in D2 progeny fed HFD did perinatal TCDD increase blood glucose and the size of mammary fat pads, while decreasing both branch elongation and the number of terminal end buds.ConclusionsWe conclude that despite having a low-responsive AHR, D2 progeny fed a diet similar to that consumed by most people are susceptible to TCDD and DMBA exposure effects blood glucose levels, mammary differentiation, and hepatic Cyp1 expression.
Can Exercise Enhance the Efficacy of Checkpoint Inhibition by Modulating Anti-Tumor Immunity?
Creators: name: Brummer, Christina
name: Pukrop, Tobias
name: Wiskemann, Joachim
name: Bruss, Christina
name: Ugele, Ines
name: Renner, Kathrin
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: physical activity (PA); exercise; cancer; immune checkpoint inhibition (ICI); PD-1; PD-L1; immunotherapy; tumor microenvironment (TME); anti-tumor immunity; T cells; NK cells
subject: 610 Medizin

description: Immune checkpoint inhibition (ICI) has revolutionized cancer therapy. However, response to ICI is often limited to selected subsets of patients or not durable. Tumors that are non-responsive to checkpoint inhibition are characterized by low anti-tumoral immune cell infiltration and a highly immunosuppressive tumor microenvironment. Exercise is known to promote immune cell circulation and improve immunosurveillance. Results of recent studies indicate that physical activity can induce mobilization and redistribution of immune cells towards the tumor microenvironment (TME) and therefore enhance anti-tumor immunity. This suggests a favorable impact of exercise on the efficacy of ICI. Our review delivers insight into possible molecular mechanisms of the crosstalk between muscle, tumor, and immune cells. It summarizes current data on exercise-induced effects on anti-tumor immunity and ICI in mice and men. We consider preclinical and clinical study design challenges and discuss the role of cancer type, exercise frequency, intensity, time, and type (FITT) and immune sensitivity as critical factors for exercise-induced impact on cancer immunosurveillance.
Camilo Castelo Branco, O Que Fazem Mulheres. 8ª edição. Parceria A. M. Pereira, Lda. Vol. de 224 ps. 130x195. Lisboa 1967
Creators: name: B., A. J.
Publisher: name: Theologica
Year: 1968

description: Theologica, v. 3 n. 3 (1968)
Adolescents' with Spina Bifida and Parents' Perceptions of Engaging in Social Activities
Creators: name: Bafail, Ranya
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: Background: Spina bifida (SB) is a congenital birth defect that adversely affects the spine and occurs in approximately three of every 10,000 live births in the United States. Little research data are available on adolescents and parents’ perceptions and expectations about social functioning of children with disabilities, particularly SB. Objectives: The aims of this study were to describe (1) the perceptions of adolescents with SB and their parents toward facilitators of and challenges to the adolescents’ social functioning, (2) parents’ perceptions and expectations of social functioning for their adolescents, and (3) adolescents’ perceptions of their parents’ expectations. Method: In this qualitative study, data were collected by conducting semi-structured interviews virtually via Zoom with 20 participants, including 10 adolescents with SB and 10 of their parents. Results: The benefits of adolescents’ engaging in social activities and having strong family relationships and support were recognized by both the adolescents and their parents. The adolescent and parent participants agreed that the adolescents encountered a variety of SB-related challenges, including stigma and bullying from other children as well as pain and skin problems. Conclusions: Nurses and other healthcare professionals should strive to maximize the social participation of adolescents with SB regardless of their physical limitations. In particular, nurses can take advantage of their interactions with parents and adolescents to discuss opportunities for the children’s social involvement. Additional nursing research is needed to determine how adolescents and parents can maximize adolescents’ engagement in social activities
Clover Nature Mills Best Organic Food Products Store in Abu Dhabi
Creators: name: Mills, Clover Nature
Publisher: name: Zenodo
Year: 2025

description: Clover Nature Mills is a leading provider of premium natural and organic food products in the UAE. With both an online store and physical locations, we offer the best e-commerce shopping and the personal touch of offline retail. Our offerings include traditional cold-pressed oils, flours, spices, nuts, dried fruits, seeds, and specialty items such as pure cow ghee and forest honey.

Our products are crafted with the finest pure and natural ingredients, ensuring they become the top choice for customers seeking premium quality. Despite our relatively recent inception, we have quickly gained the trust and loyalty of our customers through our unwavering commitment to quality and authenticity.
Biosensor transport assay for SLC1A2 using HEK293-SLC1A2-WTOE cells
Creators: name: Philipp Leippe
Publisher: name: Zenodo
Year: 2023
Subjects: Transport assay

description: This assay detects aspartate uptake using a biosensor for aspartate, cyto-iAspSnFR (Addgene #201394) in HEK293-JumpIn-TRex cells overexpressing SLC1A2. Aspartate uptake leads in an increased emission in the GFP channel that is normalized to the red fluorescent protein mScarlet-I for expression level normalization. Fluorescence detection is performed using a flow cytometer for increased throughput and high cell number statistics.
On power series expansions of the S-resolvent operator and the Taylor formula
Creators: name: Colombo, Fabrizio
name: Gantner, Jonathan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: The $S$-functional calculus is based on the theory of slice hyperholomorphic functions and it defines functions of $n$-tuples of not necessarily commuting operators or of quaternionic operators. This calculus relays on the notion of $S$-spectrum and of $S$-resolvent operator. Since most of the properties that hold for the Riesz-Dunford functional calculus extend to the S-functional calculus it can be considered its non commutative version. In this paper we show that the Taylor formula of the Riesz-Dunford functional calculus can be generalized to the S-functional calculus, the proof is not a trivial extension of the classical case because there are several obstructions due to the non commutativity of the setting in which we work that have to be overcome. To prove the Taylor formula we need to introduce a new series expansion of the $S$-resolvent operators associated to the sum of two $n$-tuples of operators. This result is a crucial step in the proof of our main results,but it is also of independent interest because it gives a new series expansion for the $S$-resolvent operators. This paper is devoted to researchers working in operators theory and hypercomplex analysis.
ReAble: a Wearable Robotic Locomotor Trainer for Post-Stroke Individuals
Creators: name: Gozzi, Alessandro
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: Background. Post-stroke individuals usually show walking impairments, including reduced walking speed and gait asymmetry. One possible reason for these impairments may be due to the reduced propulsion forces and muscle activity on the paretic leg. Different robotic systems have been developed but current rehabilitation approaches are not often effective in improving paretic leg propulsion. Objective. To develop and validate a novel wearable robotic system that is able to improve paretic propulsion in individuals post-stroke and that can be used during overground walking. Methods. This work proposes ReAble: a cable-driven soft wearable robotic system that forces the paretic leg usage by resisting to the non-paretic leg swing. The resistive force was real-time controlled by ankles kinematic wearable sensors and a load cell measurement. In addition, ReAble exploits the constraint induced movement therapy principle on the lower limb training in an innovative way allowing overgound walking training. The feasibility of the robotic locomotor training device has been tested on three healthy control subjects and one post-stroke patient. EMG signals from 8 leg muscles of the non-directly perturbed leg (the paretic leg for the patient post-stroke) and ground reaction forces of both legs were recorded to evaluate the effect on the non- perturbed/paretic leg activity. Two different walking speeds and two different timings of the resistive force were also tested to examine the characteristics of Re- Able. Results. The preliminary results show significant increases in the non-perturbed/paretic leg integrated EMG of gluteus maximus, rectus femoris, vastus medialis, biceps femoris, hip adductor and soleus when the resistive force was applied. The resistive force also induced an increase in the braking force on the non-perturbed/paretic leg, and improved propulsion force from the perturbed/non-paretic leg. In addition, the walking speed had no significant impact on muscle activity induced by the perturbation force, suggesting that it may be used on individuals post-stroke with different function levels. Conclusion. This novel soft cable-driven portable robotic system is feasible to be used to increase the paretic leg muscle activity during overground walking in individuals with poststroke hemiparesis.
ass gauging in mid-size propellant tanks
Creators: name:  R. GONZALEZ-CINCA
name:   S. ABECIA
Publisher: name: Proceedings of  the 9th European Conference for Aerospace Sciences. Lille, France, 27 June - 1 July, 2022
Year: 2022
Subjects: SPACE EXPLORATION
ISRU

description: The measurement of mass in propellant tanks of an upper stage in space is a challenge given the unknown location and shape of the liquid in microgravity. Nevertheless, an accurate measurement of mass of propellant at any stage of a mission would allow a more efficient use of this propellant. Most of current mass measurement technologies have estimation errors of up to 10 %. The spectral mass gauging (SMG) technique has been recently proposed [1, 2]. This approach is based on spectral invariants with respect to the configuration of the liquid in the reservoir. The SMG uses acoustic waves to probe the resonance frequencies of the liquid gas mixture and takes advantage of the mathematical properties of high-frequency spectral asymptotics to determine the fraction of liquid volume in the tank. In this work we present an experimental study of the application of the SMG on mid-size (300 L) tanks. Different types of acoustic actuation and data acquisition are considered. The data acquired in the experiments are analyzed following different approaches.
Disruption of MicroRNA Expression in Human Airway Cells by Diesel Exhaust Particles is Linked to Tumorigenesis-Associated Pathways
Creators: name: Diaz-Sanchez, David
name: Jaspers, Ilona
name: Fry, Rebecca
name: Jardim, Melanie
name: Dailey, Lisa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundParticulate matter (PM) is associated with adverse airway health effects; however, the underlying mechanism in disease initiation is still largely unknown. Recently, microRNAs (miRNAs; small noncoding RNAs) have been suggested to be important in maintaining the lung in a disease-free state through regulation of gene expression. Although many studies have shown aberrant miRNA expression patterns in diseased versus healthy tissue, little is known regarding whether environmental agents can induce such changes.ObjectivesWe used diesel exhaust particles (DEP), the largest source of emitted airborne PM, to investigate pollutant-induced changes in miRNA expression in airway epithelial cells. We hypothesized that DEP exposure can lead to disruption of normal miRNA expression patterns, representing a plausible novel mechanism through which DEP can mediate disease initiation.MethodsHuman bronchial epithelial cells were grown at air–liquid interface until they reached mucociliary differentiation. After treating the cells with 10 μg/cm2 DEP for 24 hr, we analyzed total RNA for miRNA expression using microarray profile analysis and quantitative real-time polymerase chain reaction.ResultsDEP exposure changed the miRNA expression profile in human airway epithelial cells. Specifically, 197 of 313 detectable miRNAs (62.9%) were either up-regulated or down-regulated by 1.5-fold. Molecular network analysis of putative targets of the 12 most altered miRNAs indicated that DEP exposure is associated with inflammatory responses pathways and a strong tumorigenic disease signature.ConclusionsAlteration of miRNA expression profiles by environmental pollutants such as DEP can modify cellular processes by regulation of gene expression, which may lead to disease pathogenesis.
Evaluation of Silver Nanoparticle Toxicity in Skin in Vivo and Keratinocytes in Vitro
Creators: name: Samberg, Meghan E.
name: Oldenburg, Steven J.
name: Monteiro-Riviere, Nancy A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: IntroductionProducts using the antimicrobial properties of silver nanoparticles (Ag-nps) may be found in health and consumer products that routinely contact skin.ObjectivesThis study was designed to assess the potential cytotoxicity of Ag-nps in human epidermal keratinocytes (HEKs) and their inflammatory and penetrating potential into porcine skin in vivo.Materials and MethodsWe used eight different Ag-nps in this study [unwashed/uncoated (20, 50, and 80 nm particle diameter), washed/uncoated (20, 50, and 80 nm), and carbon-coated (25 and 35 nm)]. Skin was dosed topically for 14 consecutive days. HEK viability was assessed by MTT, alamarBlue (aB), and CellTiter 96 AQueous One (96AQ). Release of the proinflammatory mediators interleukin (IL)-1β, IL-6, IL-8, IL-10, and tumor necrosis factor-α (TNF-α) were measured.ResultsThe effect of the unwashed Ag-nps on HEK viability after a 24-hr exposure indicated a significant dose-dependent decrease (p < 0.05) at 0.34 μg/mL with aB and 96AQ and at 1.7 μg/mL with MTT. However, both the washed Ag-nps and carbon-coated Ag-nps showed no significant decrease in viability at any concentration assessed by any of the three assays. For each of the unwashed Ag-nps, we noted a significant increase (p < 0.05) in IL-1β, IL-6, IL-8, and TNF-α concentrations. We observed localization of all Ag-nps in cytoplasmic vacuoles of HEKs. Macroscopic observations showed no gross irritation in porcine skin, whereas microscopic and ultrastructural observations showed areas of focal inflammation and localization of Ag-nps on the surface and in the upper stratum corneum layers of the skin.ConclusionThis study provides a better understanding Ag-nps safety in vitro as well as in vivo and a basis for occupational and risk assessment. Ag-nps are nontoxic when dosed in washed Ag-nps solutions or carbon coated.
Arithmetic Properties of the Frobenius Indices Associated to the Reductions of an Elliptic Curve
Creators: name: Fitzpatrick, Matthew E
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: For an elliptic curve $E$ defined over $\Q$ without complex multiplication and for a rational prime $p$ of good reduction, one can consider the subring of the $\F_p$-endomorphism ring of $E$ generated by multiplication by an integer and the Frobenius endomorphism, $\phi_p$. Defining $a_p=p+1-\#E(\F_p)$, the Frobenius endomorphism satisfies the polynomial $x^2-a_px+p$. We can associate $\phi_p$ with a $\ol\Q$-root of this polynomial, $\pi$. Realizing the endomorphism ring and its subring as orders in a quadratic field, we get the chain of orders $$\Z[\pi_p]\subseteq \End_{\F_p}(E)\subseteq \mc{O}_{\Q\left(a_p^2-4p\right)}.$$ If we define $\Delta_p$ as the discriminant of $\End_{\F_p}(E)$ and $b_p$ as the index of $\Z[\pi_p]$ inside $\End_{\F_p}(E)$, we see that $$b_p^2\Delta_p=a_p^2-4p.$$ In this thesis, we study properties of $b_p$, specifically how many divisors it has on average as $p$ varies. The relationship between $b_p$ and $\Delta_p$ allows us to use properties of $b_p$ to better understand $\Delta_p$. Assuming the generalized Riemann hypothesis, Cojocaru and Duke proved that the number of $p\le x$ such that $b_p=1$ is asymptotic to a constant multiple of $\pi(x)$. We build on this by proving that the sum of the number of divisors of $b_p$ is asymptotic to a constant multiple of $\pi(x)$ under the same assumption. We then use the relation between $b_p$ and $\Delta_p$ to prove that for almost all $p$, $|\Delta_p|$ is close to $4p-a_p^2$ when the generalized Riemann hypothesis is assumed. We also explore the constants in Cojocaru and Duke's theorem and our theorem on the number of divisors of $b_p$. We prove formulas for each constant and then prove that on average over elliptic curves without complex multiplication, these constants tend to idealized constants. Finally, we look at computational data which provides evidence for our theorems unconditionally.
Biosensor transport assay for SLC1A3 using HEK293-SLC1A3-WTOE cells
Creators: name: Philipp Leippe
Publisher: name: Zenodo
Year: 2023
Subjects: Transport assay

description: This assay detects aspartate uptake using a biosensor for aspartate, cyto-iAspSnFR (Addgene #201394) in HEK293-JumpIn-TRex cells overexpressing SLC1A3. Aspartate uptake leads in an increased emission in the GFP channel that is normalized to the red fluorescent protein mScarlet-I for expression level normalization. Fluorescence detection is performed using a flow cytometer for increased throughput and high cell number statistics.
High-precision theory for top-quark production
Creators: name: Kidonakis, Nikolaos
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: I present high-precision results for top quark production at hadron collider energies. Total and differential cross sections are calculated through aN$^3$LO for top-antitop pair production and through aNNLO for single-top production. Top production in association with a charged Higgs boson and via anomalous couplings is also briefly discussed.
description: 11 pages, 13 figures; presented at the XIII International Conference on Heavy Quarks and Leptons (HQL2016), Blacksburg, Virginia, May 22-27, 2016; v2 has minor changes
Alexa, Teach my Kid Fractions: A Single-Case Study using Conversational Assistant’s to Support Learning
Creators: name: Emerling, Christopher R
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: The National Center on Education Statistics (2019) reports that of the nearly 7 million students who have qualified for special education services, 34% identify with a specific learning disability (LD). This study aimed to investigate the extent to which a conversational assistant (Amazon Alexa) programed with the self-regulated strategy development (SRSD) mnemonic had on students who were at-risk for LD and performing below grade level in mathematics. The study recruited four elementary-age students in a local catholic school between the ages of 10-11. Participants all performed below grade level on the ACT aspire formative assessment and received Title 1 services for weekly academic support for mathematics. The study used single-case multiple probes across the participant’s research design to evaluate academic performance on fraction probes across phases. Descriptive data were also collected for academic engagement and duration. Visual and statistical analysis were used to analyze the data and determine a functional relation between the technology-supported SRSD intervention and the primary dependent variable, academic performance, for all four participants. Implications for practice and several limitations are also discussed.
Evidence That Humans Metabolize Benzene via Two Pathways
Creators: name: Rappaport, Stephen M.
name: Li, Guilan
name: Yin, Songnian
name: Waidyanatha, Suramya
name: Rothman, Nathaniel
name: Lan, Qing
name: Hayes, Richard B.
name: Kim, Sungkyoon
name: Zhang, Luoping
name: Smith, Martyn T.
name: Vermeulen, Roel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundRecent evidence has shown that humans metabolize benzene more efficiently at environmental air concentrations than at concentrations > 1 ppm. This led us to speculate that an unidentified metabolic pathway was mainly responsible for benzene metabolism at ambient levels.ObjectiveWe statistically tested whether human metabolism of benzene is better fitted by a kinetic model having two pathways rather than one.MethodsWe fit Michaelis-Menten-like models to levels of urinary benzene metabolites and the corresponding air concentrations for 263 nonsmoking Chinese females. Estimated benzene concentrations ranged from less than 0.001 ppm to 299 ppm, with 10th and 90th percentile values of 0.002 ppm and 8.97 ppm, respectively.ResultsUsing values of Akaike’s information criterion obtained under the two models, we found strong statistical evidence favoring two metabolic pathways, with respective affinities (benzene air concentrations analogous to Km values) of 301 ppm for the low-affinity pathway (probably dominated by cytochrome P450 enzyme 2E1) and 0.594 ppm for the high-affinity pathway (unknown). The exposure-specific metabolite level predicted by our two-pathway model at nonsaturating concentrations was 184 μM/ppm of benzene, a value close to an independent estimate of 194 μM/ppm for a typical nonsmoking Chinese female. Our results indicate that a nonsmoking woman would metabolize about three times more benzene from the ambient environment under the two-pathway model (184 μM/ppm) than under the one-pathway model (68.6 μM/ppm). In fact, 73% of the ambient benzene dose would be metabolized via the unidentified high-affinity pathway.ConclusionBecause regulatory risk assessments have assumed nonsaturating metabolism of benzene in persons exposed to air concentrations well above 10 ppm, our findings suggest that the true leukemia risks could be substantially greater than currently thought at ambient levels of exposure—about 3-fold higher among nonsmoking females in the general population.
Theoretical results for top-quark cross sections and distributions
Creators: name: Kidonakis, Nikolaos
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: I present new results and updates for total cross sections and differential distributions in top-antitop pair and single-top production. Soft-gluon corrections are added to exact fixed-order results to provide the best predictions at approximate N$^3$LO for $t{\bar t}$ production and approximate NNLO for single-top production. Total cross sections and top-quark transverse-momentum and rapidity distributions are presented and compared with data at LHC and Tevatron energies. The cusp anomalous dimension at three and higher loops is also discussed.
description: 6 pages, 7 figures; presented at the 38th International Conference on High Energy Physics (ICHEP 2016), Chicago, Illinois, August 3-10, 2016
title: Impact of care pathways on the care of people with diabetes mellitus
Creators: name: Victoria O'Brien, Sarah
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis aimed to develop care pathways for the management of in-patients and outpatients with diabetes in an acute NHS Trust, to review the evidence-base for existing care pathways and to evaluate the impact of care pathways on the management of in-patients with diabetes and patients with Diabetic Nephropathy. A comprehensive literature review (using the principles of a systematic review) was completed to determine whether care pathways improved the management and or outcome of hospital in-patients with a medical or surgical condition. From this review it appears that the main potential benefits associated with the introduction of a care pathway are a reduction in length of stay, reduced costs and possible improvements in the quality of patient care. However, these findings are limited because of the poor methodology used in all of the papers reviewed and there is a need for more robust research concerning care pathways. This work has provided a systematic process for developing diabetes care pathways and examples of diabetes care pathways that could be used and adapted by other clinicians managing patients with diabetes. A randomised controlled trial examined the impact of the in-patient diabetes care pathway on HbA1c, length of stay, re-admissions within 12 months, nurse knowledge and the quality of in-patient care. In terms of the primary endpoint of HbA 1c, the null hypothesis cannot be rejected as there was no difference between the study groups. In the main, secondary endpoints improved, but limitations in the design and execution of the study preclude excessive weight being attached to these findings. Furthermore, completion of the care pathway was poor and sustaining its ongoing use outside of a research study may be difficult, further work is needed to assess the cost of wider implementation of this care pathway. A care pathway-driven Diabetic Nephropathy service was developed, implemented and evaluated to examine whether it resulted in improvements in the management of Diabetic Kidney Disease (DKD). The results demonstrated successful implementation of six key evidence-based interventions for DKD and more importantly both surrogate and hard endpoints were comparable to those achieved in recent large clinical trials, in particular, the rate of doubling of serum creatinine, progression to End Stage Renal Failure and Death. This thesis demonstrates that in some circumstances care pathways can improve implementation of evidence-based diabetes care and lead to improvements in patient outcomes. Care pathways appear to be particularly useful when used by a dedicated, appropriately trained team dealing primarily with one condition, and can be an effective tool for the implementation of evidence-based diabetes care. Further work examining the impact of care pathways in all areas of health care would be useful.
Exploring approximations to the GW self-energy ionic gradients
Creators: name: Faber, C.
name: Boulanger, P.
name: Attaccalite, C.
name: Cannuccia, E.
name: Duchemin, I.
name: Deutsch, T.
name: Blase, X.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The accuracy of the many-body perturbation theory GW formalism to calculate electron-phonon coupling matrix elements has been recently demonstrated in the case of a few important systems. However, the related computational costs are high and thus represent strong limitations to its widespread application. In the present study, we explore two less demanding alternatives for the calculation of electron-phonon coupling matrix elements on the many-body perturbation theory level. Namely, we test the accuracy of the static Coulomb-hole plus screened-exchange (COHSEX) approximation and further of the constant screening approach, where variations of the screened Coulomb potential W upon small changes of the atomic positions along the vibrational eigenmodes are neglected. We find this latter approximation to be the most reliable, whereas the static COHSEX ansatz leads to substantial errors. Our conclusions are validated in a few paradigmatic cases: diamond, graphene and the C60 fullerene. These findings open the way for combining the present many-body perturbation approach with efficient linear-response theories.
Further analyses and controlls from Recognition of small numbers in subset knowers Cardinal knowledge in early childhood
Creators: name: Gerbrand, Anton
name: Gredebäck, Gustaf
name: Lindskog, Marcus
Publisher: name: The Royal Society
Year: 2023
Subjects: classificationCode: 520499
subject: Cognitive and computational psychology not elsewhere classified
classificationCode: 529999
subject: Other psychology not elsewhere classified

description: A supplementary where we describe the samples further, and perform a series of controls, as well as some exploratory analyses
Increased Nonconducted P-Wave Arrhythmias after a Single Oil Fly Ash Inhalation Exposure in Hypertensive Rats
Creators: name: Costa, Daniel L.
name: Rowan, William H.
name: Cascio, Wayne E.
name: Hazari, Mehdi S.
name: Carll, Alex P.
name: Haykal-Coates, Najwa
name: Winsett, Darrell W.
name: Farraj, Aimen K.
name: Ledbetter, Allen D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundExposure to combustion-derived fine particulate matter (PM) is associated with increased cardiovascular morbidity and mortality especially in individuals with cardiovascular disease, including hypertension. PM inhalation causes several adverse changes in cardiac function that are reflected in the electrocardiogram (ECG), including altered cardiac rhythm, myocardial ischemia, and reduced heart rate variability (HRV). The sensitivity and reliability of ECG-derived parameters as indicators of the cardiovascular toxicity of PM in rats are unclear.ObjectiveWe hypothesized that spontaneously hypertensive (SH) rats are more susceptible to the development of PM-induced arrhythmia, altered ECG morphology, and reduced HRV than are Wistar Kyoto (WKY) rats, a related strain with normal blood pressure.MethodsWe exposed rats once by nose-only inhalation for 4 hr to residual oil fly ash (ROFA), an emission source particle rich in transition metals, or to air and then sacrificed them 1 or 48 hr later.ResultsROFA-exposed SH rats developed nonconducted P-wave arrhythmias but no changes in ECG morphology or HRV. We found no ECG effects in ROFA-exposed WKY rats. ROFA-exposed SH rats also had greater pulmonary injury, neutrophil infiltration, and serum C-reactive protein than did ROFA-exposed WKY rats.ConclusionsThese results suggest that cardiac arrhythmias may be an early sensitive indicator of the propensity for PM inhalation to modify cardiovascular function.
Generalizations of self-reciprocal polynomials
Creators: name: Mattarei, Sandro
name: Pizzato, Marco
Publisher: name: arXiv
Year: 2016
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 12E05

description: A formula for the number of monic irreducible self-reciprocal polynomials, of a given degree over a finite field, was given by Carlitz in 1967. In 2011 Ahmadi showed that Carlitz's formula extends, essentially without change, to a count of irreducible polynomials arising through an arbitrary quadratic transformation. In the present paper we provide an explanation for this extension, and a simpler proof of Ahmadi's result, by a reduction to the known special case of self-reciprocal polynomials and a minor variation. We also prove further results on polynomials arising through a quadratic transformation, and through some special transformations of higher degree.
description: 17 pages. The paper has been mildly re-organized according to suggestions of various referees, improving clarity. This version matches the published version
Annotation scheme and guide for antisemitism and conspiracy theory in online texts
Creators: name: Steffen, Elisabeth
name: Mihaljević, Helena
Publisher: name: Zenodo
Year: 2022
Subjects: annotation guide; annotation scheme; labeling; antisemitism; conspiracy theory

description: This annotation scheme and guide were developed as part of ‘Digitaler Hass’, an interdisciplinary project of Hochschule für Technik und Wirtschaft (HTW) Berlin and Alice Salomon University (ASH) Berlin, that studies antisemitism, racism and conspiracy theories in online text corpora. The central goal of this document is to facilitate the annotation of online texts such as those published via messenger services or social media platforms with regard to occurrences of antisemitic and conspiracy theoretical statements. We have focused on narratives that are typical of pandemics such as the COVID-19 pandemic. The examples in the guide are mostly in German, as one of the goals of the project is to foster research based on large German-language corpora.
Centering the Voices of People with Intellectual and Developmental Disabilities about Family Support
Creators: name: Arnold, Catherine K
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: The perspectives of people with intellectual and developmental disabilities (IDD) are missing from the family support literature. The purpose of this study was to center the voices of people with IDD to learn about family support from their viewpoint. Two main research questions were explored: (1) What types of support do people with IDD receive from their families?; and (2) What types of support do people with IDD provide to their families? This research study applied a conceptual framework that incorporated life course theory grounded in a Disability Studies approach using participatory action research. The participatory action research (PAR) process included a Community Advisory Committee comprised of five adults with IDD who guided the research. Accessible methods were used to ensure the voices of people with IDD were included and centered in the research. Thirty virtual interviews were conducted using the dyadic interview method with 10 adults with IDD and 10 key support people who they chose. Two primary themes emerged from the data. First, the theme of social-emotional support encompassed ways people with IDD both received and provided companionship support and emotional support to their families. Second, the theme of independent living support included ways people with IDD received and provided instrumental support and information support from and to their families. There are two significant areas for implications from this research study. First, that families provide a vast amount of support to people with IDD and therefore more focus should be on ways to support these families. Second, people with IDD provide important support to their families that should be acknowledged and valued for their reciprocal contributions. This study provides recommendations for changes in systems and policies as well as future directions in research.
Dufoyer, Pierre, A Alma da Criança. Editorial Aster - Colecção Família e Educação. Vol. de 210 ps. 135x200. 1ª e 2ª edições. Lisboa 1966 e 1968
Creators: name: Emílio, António
Publisher: name: Theologica
Year: 1968

description: Theologica, v. 3 n. 3 (1968)
Individual Characteristics Associated with PBDE Levels in U.S. Human  Milk Samples
Creators: name: Needham, Larry L.
name: Anderson, Sarah
name: Jones, Richard
name: Patterson, Donald G.
name: Daniels, Julie L.
name: Pan, I-Jen
name: Sjödin, Andreas
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundReported polybrominated diphenyl ether (PBDE) concentrations in human samples in the United States have been higher than in Europe and Asia. Little is known about factors that contribute to individual variability in body burden.ObjectiveIn this large study we measured PBDE concentrations in human milk from the United States during 2004–2006. We assessed characteristics associated with concentrations in milk and change in milk concentration between 3 and 12 months postpartum.MethodsWe analyzed 303 milk samples obtained 3 months postpartum for PBDEs. A second sample was analyzed for 83 women still lactating 12 months postpartum. PBDE concentrations in milk and variability by individual characteristics such as age, parity, and prepregnancy body mass index (BMI) were evaluated using generalized linear models.ResultsPBDE congeners BDEs 28, 47, 99, 100, and 153 were detected in > 70% of samples. BDE-47 concentrations were the highest, ranging from below the limit of detection to 1,430 ng/g lipid, with a median of 28 ng/g lipid. Concentrations of most individual PBDE congeners and the sum of BDEs 28, 47, 99, 100, and 153 (∑PBDE) were lower among mothers > 34 years of age compared with those 25–29 years of age and higher among mothers with high compared with normal BMI, after adjustment for other covariates. Parity was not associated with PBDE concentration. The change in ∑PBDE concentration in milk between 3 and 12 months postpartum was highly variable (median increase, 14%; interquartile range, −26% to 50%).ConclusionsPBDEs were detected in nearly all human milk samples, varying by maternal weight and age and over the course of breast-feeding.
Lactational Exposure to Polychlorinated Biphenyls, Dichlorodiphenyltrichloroethane, and Dichlorodiphenyldichloroethylene and Infant Neurodevelopment: An Analysis of the Pregnancy, Infection, and Nutrition Babies Study
Creators: name: Pan, I-Jen
name: Herring, Amy H.
name: Goldman, Barbara D.
name: Daniels, Julie L.
name: Siega-Riz, Anna Maria
name: Rogan, Walter J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundPolychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT) are persistent, bioaccumulative, and toxic pollutants that were broadly used in the United States until the 1970s. Common exposure to PCBs, DDT, and dichlorodiphenyldichloroethylene (DDE), the most stable metabolite of DDT, may influence children’s neurodevelopment, but study results are not consistent.ObjectivesWe examined the associations between lactational exposure to PCBs, DDT, and DDE and infant development at 12 months, using data from the Pregnancy, Infection, and Nutrition Babies Study, 2004–2006.MethodsWe measured PCBs, DDT, and DDE in breast milk at the third month postpartum. Lactational exposure of these chemicals was estimated by the product of chemical concentrations and the duration of breast-feeding. Infant development at 12 months of age was measured by the Mullen Scales of Early Learning (n = 231) and the Short Form: Level I (infant) of the MacArthur–Bates Communicative Development Indices (n = 218).ResultsNo consistent associations were observed between lactational exposure to PCBs, DDT, and DDE through the first 12 months and the measures of infant development. However, DDE was associated with scoring below average on the gross motor scale of the Mullen among males only (adjusted odds ratio = 1.9; 95% confidence interval, 1.1–3.3).ConclusionInfant neurodevelopment at 12 months of age was not impaired by PCBs, DDT, and DDE at the concentrations measured here, in combination with benefits from long duration of breast-feeding in this population.