cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Pterophthirus Ewing 1923
Creators: name: Valim, Michel P.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Psocodea
Hoplopleuridae
Pterophthirus

description: Genus Pterophthirus Ewing, 1923: 147
 Pterophthirus wernecki Guimarães, 1950a: 83. Holotype: male; #46,016; b.5.77; Allotype: female; #46,017; b.5.78; Paratypes: 1 male and 1 female; #46,024; b.5.85; Paratypes: 1 male and 1 female; #46,025; b.5.86; Paratypes: 1 male and 1 female; #46,026; b.5.87; Paratypes: 1 male and 1 female; Paratypes: specimens of both sexes; #46,027; a.6.62; #46,028; a.6.63; #46,029; a.6.64; #46,030; a.6.65; Note 1,297. Ex Proechimys i. iheringi (= Trinomys iheringi (Thomas, 1911)) (Rodentia: Echimyidae). Brazil, São Paulo, Boracéia, 16.viii.1948; Travassos Filho, L. & Fonseca, O. cols.
 Family Pediculidae Leach, 1817
description: Published as part of Valim, Michel P., 2009, Type specimens of lice (Insecta: Phthiraptera) held in the Museu de Zoologia da Universidade de São Paulo, Brazil Michel P. Valim ABSTRACT, pp. 197-219 in Papéis Avulsos de Zoologia (São Paulo) (São Paulo) 49 (17) on page 213, DOI: 10.1590/S0031-10492009001700001, http://zenodo.org/record/13313791
Appendix_1 – Supplemental material for Characteristics of patients with systemic sclerosis suffering from a lower limb amputation: Results of a French collaborative study
Creators: name: Bertolino, Julien
name: Jouve, Elisabeth
name: Skopinski, Sophie
name: Agard, Christian
name: Achille, Aurélie
name: Thoreau, Benjamin
name: Diot, Elisabeth
name: Sanges, Sebastien
name: Berthier, Sabine
name: Chaigne, Benjamin
name: Régent, Alexis
name: Martin, Thierry
name: Pugnet, Gregory
name: Benyamine, Audrey
name: Rossi, Pascal
name: Launay, David
name: Mouthon, Luc
name: Granel, Brigitte
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110322 Rheumatology and Arthritis
subject: FOS: Clinical medicine

description: Supplemental material, Appendix_1 for Characteristics of patients with systemic sclerosis suffering from a lower limb amputation: Results of a French collaborative study by Julien Bertolino, Elisabeth Jouve, Sophie Skopinski, Christian Agard, Aurélie Achille, Benjamin Thoreau, Elisabeth Diot, Sebastien Sanges, Sabine Berthier, Benjamin Chaigne, Alexis Régent, Thierry Martin, Gregory Pugnet, Audrey Benyamine, Pascal Rossi, David Launay, Luc Mouthon and Brigitte Granel in Journal of Scleroderma and Related Disorders
sj-pdf-1-dhj-10.1177_2055207620922381 - Supplemental material for Evaluation of a web-based, tailored intervention to encourage help-seeking for lung cancer symptoms: a randomised controlled trial
Creators: name: Mueller, Julia
name: Davies, Alan
name: Jay, Caroline
name: Harper, Simon
name: Todd, Chris
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111099 Nursing not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 111702 Aged Health Care
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies
subject: Anthropology
subject: FOS: Sociology
subject: 200299 Cultural Studies not elsewhere classified
subject: FOS: Other humanities
subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences
subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: Science Policy
subject: 160512 Social Policy
subject: FOS: Political science
subject: Sociology

description: Supplemental material, sj-pdf-1-dhj-10.1177_2055207620922381 for Evaluation of a web-based, tailored intervention to encourage help-seeking for lung cancer symptoms: a randomised controlled trial by Julia Mueller, Alan Davies, Caroline Jay, Simon Harper and Chris Todd in Digital Health
uADD_supplemental_appendix_v02_1 – Supplemental material for Preference for Alternate-Day Versus Conventional In-Center Dialysis: A Health Utility Elicitation
Creators: name: Solimano, Rafael J.
name: Lineen, James
name: Naimark, David M. J.
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental material, uADD_supplemental_appendix_v02_1 for Preference for Alternate-Day Versus Conventional In-Center Dialysis: A Health Utility Elicitation by Rafael J. Solimano, James Lineen and David M. J. Naimark in Canadian Journal of Kidney Health and Disease
title: New onset pectus carinatum secondary to osteomalacia
Creators: name: Samra, Ivjot
Publisher: name: EURORAD
Year: 2024
Subjects: subject: Chest imaging
subject: Bones
subject: Musculoskeletal bone
subject: Thorax
subject: CT
subject: Clinical Case

description: Clinical History: A 70-year-old previously healthy female presented to the emergency department (ED) with acute chronic dyspnoea and inability to mobilise after sustaining a fall three weeks prior. The physical exam revealed a new pectus carinatum (PC) deformity with bilateral air entry.

description: 70 years, female
Appendix_-_all_tables_and_figures_-_final_submitted – Supplemental material for The art of stage-craft: A dramaturgical perspective on strategic change
Creators: name: Whittle, Andrea
name: Gilchrist, Alan
name: Mueller, Frank
name: Lenney, Peter
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material, Appendix_-_all_tables_and_figures_-_final_submitted for The art of stage-craft: A dramaturgical perspective on strategic change by Andrea Whittle, Alan Gilchrist, Frank Mueller and Peter Lenney in Strategic Organization
In-silico studies of 2-aminothiazole derivatives as anticancer agents by QSAR, molecular docking, MD simulation and MM-GBSA approaches
Creators: name: Chitre, Trupti S.
name: Hirode, Purvaj V.
name: Lokwani, Deepak K.
name: Bhatambrekar, Aniket L.
name: Hajare, Sayli G.
name: Thorat, Shubhangi B.
name: Priya, D.
name: Pradhan, Kunal B.
name: Asgaonkar, Kalyani D.
name: Jain, Shirish P.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Targeting Hec1/Nek2 is considered as crucial target for cancer treatment due to its significant role in cell proliferation. In pursuit of this, a series of twenty-five 2-aminothiazoles derivatives, along with their Hec1/Nek2 inhibitory activities were subjected to QSAR studies utilizing QSARINS software. The significant three descriptor QSAR model was generated, showing noteworthy statistical parameters: a correlation coefficient of cross validation leave one out (Q2LOO) = 0.7965, coefficient of determination (R2) = 0.8436, (R2ext) = 0.6308, cross validation leave many out (Q2LMO) = 0.7656, Concordance Correlation Coefficient (CCCCV = 0.8875), CCCtr = 0.9151, and CCCext = 0.0.7241. The descriptors integral to generated QSAR model include Moreau-Broto autocorrelation, which represents the spatial autocorrelation of a property along the molecular graph’s topological structure (ATSC1i), Moran autocorrelation at lag 8, which is weighted by charges (MATS8c) and RPSA representing the total molecular surface area. It was noted that these descriptors significantly influence Hec1/Nek2 inhibitory activity of 2-aminothiazoles derivatives. New lead molecules were designed and predicted for their Hec1/Nek2 inhibitory activity based on the developed three descriptor model. Further, the ADMET and Molecular docking studies were carried out for these designed molecules. The three molecules were selected based on their docking score and further subjected for MD simulation studies. Post-MD MM-GBSA analysis were also performed to predicted the free binding energies of molecules. The study helped us to understand the key interactions between 2-aminothiazoles derivatives and Hec1/Nek2 protein that may be necessary to develop new lead molecules against cancer. Communicated by Ramaswamy H. Sarma
sj-pdf-1-shr-10.1177_2054270419894817 - Supplemental material for Blood sampled from existing peripheral IV cannulae yields results equivalent to venepuncture: a systematic review
Creators: name: Lesser, Finnian D
name: Lanham, David A
name: Davis, Daniel
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental material, sj-pdf-1-shr-10.1177_2054270419894817 for Blood sampled from existing peripheral IV cannulae yields results equivalent to venepuncture: a systematic review by Finnian D Lesser, David A Lanham and Daniel Davis in JRSM Open
Additional file 1 of Sea ice directs changes in bowhead whale phenology through the Bering Strait
Creators: name: Szesciorka, Angela R.
name: Stafford, Kathleen M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Astronomical and Space Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1. Supplementary tables with additional information, including migration dates and days absent for each season using different cutoffs; linear regressions between migration dates and days absent with other sea ice area metrics; and cross-correlations among sea ice area metrics.
Pharmacological network study on the effect of 6-gingerol on cervical cancer using computerized databases
Creators: name: Martínez-Esquivias, Fernando
name: Guzmán-Flores, Juan Manuel
name: Chávez-Díaz, Ismael Fernando
name: Iñiguez-Muñoz, Laura Elena
name: Reyes-Chaparro, Andrés
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Cervical cancer (CC) is the most frequent cancer in the female population worldwide. Although there are treatments available, they are ineffective and cause adverse effects. 6-gingerol is an active component in ginger with anticancer activity. This research aims to discover the mechanism by which 6-gingerol act as an anticancer agent on CC through a pharmacological network using bioinformatics databases. From MalaCard, Swiss Target Prediction, Comparative Toxicogenomics Database, and Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform, we obtained the target genes for 6-gingerol and CC and matched them. We got 26 genes and analyzed them in ShinyGO-0.76.3 and DAVID-Bioinformatics Resources. Then, we generated a protein-protein interaction network in Cytoscape and obtained 12 hub genes. Hub genes were analyzed in Gene Expression Profiling Interactive Analysis and TISIDB. In addition, molecular docking studies were performed between target proteins with 6-gingerol using SwissDock database. Finally, molecular dynamics studies for three proteins with the lowest interaction energy were implemented using Gromacs software. According to gene ontology results, 6-gingerol is involved in processes of apoptosis, cell cycle, and protein kinase complexes, affecting mitochondria and pathways related to HPV infection. CTNNB1 gene was negatively correlated with CD8+ infiltration but was not associated with a higher survival rate. Furthermore, the molecular docking study showed that 6-gingerol has a high binding to proteins, and the molecular dynamics showed a stable interaction of 6-gingerol to AKT1, CCNB1, and CTNNB1 proteins. Conclusion, our work helps to understand the anticancer activity of 6-gingerol in CC that should be studied experimentally. Communicated by Ramaswamy H. Sarma
supplementary_material_907438 – Supplemental material for Incidence of early intra-cranial bleeding and ischaemia in adult veno-arterial extracorporeal membrane oxygenation and extracorporeal cardiopulmonary resuscitation patients: a retrospective analysis of risk factors
Creators: name: Malfertheiner, Maximilian Valentin
name: Koch, Andrea
name: Fisser, Christoph
name: Millar, Jonathan Edward
name: Maier, Lars Sigfried
name: Zeman, Florian
name: Poschenrieder, Florian
name: Lubnow, Matthias
name: Philipp, Alois
name: Müller, Thomas
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Cardiology
subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, supplementary_material_907438 for Incidence of early intra-cranial bleeding and ischaemia in adult veno-arterial extracorporeal membrane oxygenation and extracorporeal cardiopulmonary resuscitation patients: a retrospective analysis of risk factors by Maximilian Valentin Malfertheiner, Andrea Koch, Christoph Fisser, Jonathan Edward Millar, Lars Sigfried Maier, Florian Zeman, Florian Poschenrieder, Matthias Lubnow, Alois Philipp and Thomas Müller in Perfusion
Additional file 1 of Mixed infection of ITPase-encoding potyvirid and secovirid in Mercurialis perennis: evidences for a convergent euphorbia-specific viral counterstrike
Creators: name: Mahillon, Mathieu
name: Brodard, Justine
name: Dubuis, Nathalie
name: Gugerli, Paul
name: Blouin, Arnaud G.
name: Schumpp, Olivier
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Figure S1. Reads counts (RC) on the viral contigs associated with MMV (blue), MSV1 (orange), MPV1 (green). CP: contig position. Figure S2. Uncropped gels used for the Figure 1G. Figure S3. ML phylogenetic tree for the CP of MSV1 and related viruses. The tree was built using the substitution model rtREV+F+G4. Black circles on branches indicate >75 % bootstrap support (1000 replicates). The scale is given in substitution per site. Members of the genus Satsumavirus were used to root the initial tree. Table S1. Primers used in this study. Table S2. BlastX report for the viral contigs identified in the HST analysis of M. perennis. Table S3. Domains and homology identified on the viral ORFs of MMV, MSV1 and MPV1. Table S4. Accession numbers for the proteins used for the phylogenetic analyses of the Potyviridae. Table S5. Accession numbers for the proteins used for the phylogenetic analyses of the Secoviridae. Table S6. Accession numbers for the RdRp used for the phylogenetic analyses of the Partitiviridae. Table S7. Accession numbers for the ITPases of the euphorbias. Table S8. Most significant (non-viral) BlastP hits for the phytoviral ITPases.
An exploration of binding of Hesperidin, Rutin, and Thymoquinone to acetylcholinesterase enzyme using multi-level computational approaches
Creators: name: Mir, Showkat Ahmad
name: Nayak, Binata
name: Khan, Andleeb
name: Khan, Mohammad Imran
name: Eldakhakhny, Basmah M.
name: Arif, Deema O.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Alzheimer’s disease, an intricate neurological disorder, is impacting an ever-increasing number of individuals globally, particularly among the aging population. For several decades phytochemicals were used as Ayurveda to treat both communicable and non-communicable diseases. Acetylcholinesterase (AChE) is a widely chosen therapeutic target for the development of early prevention and effective management of neurodegenerative diseases. The primary objective of the present study was to investigate the binding potential between Rutin Thymoquinone, Hesperidin and the FDA-approved drug Donepezil with AChE. Additionally, a comparative analysis was conducted. These phytochemicals were docked with the binding site of the AChE experimental complex. The molecular dockings demonstrated that the Hesperidinh showed a better binding affinity of −22.0631 kcal/mol. The ADME/T investigations revealed that the selected phytochemicals are non-toxic and drug-like candidates. Molecular dynamics simulations were implemented to determine the conformational changes of Rutin, hesperidin, Thymoquinone, and Donepezil complexed with AChE. Hesperidin and Donepezil were more stable than Rutin, Thymoquinone complexed with AChE. Next, essential dynamics and defining the secondary structure of protein were to determine the conformational changes in AChE complexed with selected phytochemicals during simulations. Overall, the MD Simulations demonstrated that all complexes in this study achieved stability until 100 ns of the simulation period was performed thrice. The structural analysis of AChE was done using multiple search engines to explore the molecular functions, biological processes, and pathways in which AChE proteins are involved and to identify potential drug targets for various diseases. This present study concludes that Hesperidin was found to be a more potent AChE inhibitors than Rutin, and further experiments are required to determine the effectivity of Hesperidin against neurodegenerative diseases. Communicated by Ramaswamy H. Sarma
Arylcoumarin and novel biscoumarin derivatives as potent inhibitors of human glutathione S-transferase
Creators: name: Ozalp, Lalehan
name: Orhan, Berk
name: Alparslan, Mustafa Muhlis
name: Meletli, Furkan
name: Çakmakçı, Emrah
name: Danış, Özkan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: A series of arylcoumarin derivatives and two novel biscoumarin derivatives were investigated for their human recombinant glutathione S-transferase P1-1 (GSTP1-1) enzyme inhibitory activities for the first time. 4-(3,4-Dihydroxyphenyl)-6,7-dihydroxycoumarin (compound 24) was observed to be the most active coumarin derivative (IC50: 0.14 µM). The inhibition was found to be time-dependent and irreversible. Hypothetical binding modes of the ten most active compounds were calculated by molecular docking. Ligand efficiency indices (LEI) were estimated to better understand the binding performance of the coumarin derivatives. Extensive structure-activity relationship studies showed that hydroxy substitution on both the coumarin and the aryl ring enhanced the biological activity and the position of hydroxy group on the coumarin ring is critical for the binding pose and the activity. Top three ligands were subjected to molecular dynamics simulations and MM/PBSA for further investigation. Binding mode of compound 24 suggested that its high inhibitory activity might be attributed to its position between Tyr7 and the cofactor, glutathione (GS-DNB). Exhibiting favorable druglikeness profiles and pharmacokinetics based on ADME studies, compound 5 and 24 can be considered as potential drug leads in future studies for further development. Communicated by Ramaswamy H. Sarma
Appendix_A – Supplemental material for A Thematic Analysis of Parents’ Gendered Beliefs About Emotion in Middle Childhood Boys and Girls
Creators: name: Thomassin, Kristel
name: Bucsea, Oana
name: K. Jacky Chan
name: Carter, Emma
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 160301 Family and Household Studies
subject: FOS: Sociology
subject: Sociology

description: Supplemental material, Appendix_A for A Thematic Analysis of Parents’ Gendered Beliefs About Emotion in Middle Childhood Boys and Girls by Kristel Thomassin, Oana Bucsea, K. Jacky Chan and Emma Carter in Journal of Family Issues
Enhanced activity of Candida antarctica lipase B in cholinium aminoate ionic liquids: a combined experimental and computational analysis
Creators: name: Chan, Kam Khong
name: Sundaram, Vidya
name: Tan, Jully
name: Ho, Yong Kuen
name: Ramanan, Ramakrishnan Nagasundara
name: Ooi, Chien Wei
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Science Policy
Information Systems not elsewhere classified

description: As a class of ionic liquids with higher biocompatibility, cholinium aminoates ([Cho][AA]) hold potential as solvation media for enzymatic bioprocessing. Herein, solvation effect of [Cho][AA] on structural stability and enzymatic activity of Candida antarctica lipase B (CALB) was evaluated using experimental and computational approaches. Influence of [Cho][AA] on CALB stability was investigated using amino acid anions ([AA]-) with varying hydrophobicity levels. Choline phenylalaninate ([Cho][Phe]) resulted in 109.1% and 110.4% of relative CALB activity to buffer medium at 25 °C and 50 °C, respectively. Simulation results revealed the improvement of CALB’s enzymatic activities by [AA]- with a strong hydrophobic character. Shielding of CALB from water molecules by [AA]- was observed. The level of CALB activity was governed by accumulation level of [AA]- at CALB’s first hydration layer. The stronger interaction between His224 and Asp187 was postulated to be driven by [Cho][AA], resulting in the activity enhancement of CALB. The slight improvement of CALB activity in 0.05 M [Cho][Phe] at 50 °C could be due to the larger size of entrance to the catalytic site and the stronger interaction between the catalytic residues. The promising effect of [Cho][Phe] on CALB activation may stimulate research efforts in designing a ‘fully green’ bioreaction for various industrial applications. Communicated by Ramaswamy H. Sarma
Additional file 1 of Overwintering aggregation patterns of European catfish Silurus glanis
Creators: name: Westrelin, Samuel
name: Moreau, Mathieu
name: Fourcassié, Vincent
name: Santoul, Frédéric
Publisher: name: figshare
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1 Synchronized tracks of European catfish over the four winters 2017 to 2020 in “Etang des Aulnes” https://doi.org/10.57745/U7UG5D .
Online_Appendix – Supplemental material for Who is most influential? Adolescents’ intergroup attitudes and peer influence within a social network
Creators: name: Zingora, Tibor
name: Stark, Tobias H.
name: Flache, Andreas
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Online_Appendix for Who is most influential? Adolescents’ intergroup attitudes and peer influence within a social network by Tibor Zingora, Tobias H. Stark and Andreas Flache in Group Processes & Intergroup Relations
High potential for biomass-degrading CAZymes revealed by pine forest soil metagenomics
Creators: name: Kumari, Sonam
name: Magdaleno, Jorge S. Leon
name: Grewal, Ravneet Kaur
name: Rao, Manik Prabhu Narsing
name: Shaikh, Abdul Rajjak
name: Cavallo, Luigi
name: Chawla, Mohit
name: Kumar, Manoj
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: The undisturbed environment in Netarhat, with its high levels of accumulated lignocellulosic biomass, presents an opportunity to identify microbes for biomass digestion. This study focuses on the bioprospecting of native soil microbes from the Netarhat forest in Jharkhand, India, with the potential for lignocellulosic substrate digestion. These biocatalysts could help overcome the bottleneck of biomass saccharification and reduce the overall cost of biofuel production, replacing harmful fossil fuels. The study used metagenomic analysis of pine forest soil via whole genome shotgun sequencing, revealing that most of the reads matched with the bacterial species, very low percentage of reads (0.1%) belongs to fungal species, with 13% of unclassified reads. Actinobacteria were found to be predominant among the bacterial species. MetaErg annotation identified 11,830 protein family genes and 2 metabolic marker genes in the soil samples. Based on the Carbohydrate Active EnZyme (CAZy) database, 3,996 carbohydrate enzyme families were identified, with family Glycosyl hydrolase (GH) dominating with 1,704 genes. Most observed GH families in the study were GH0, 3, 5, 6. 9, 12. 13, 15, 16, 39, 43, 57, and 97. Modelling analysis of a representative GH 43 gene suggested a strong affinity for cellulose than xylan. This study highlights the lignocellulosic digestion potential of the native microfauna of the lesser-known pine forest of Netarhat. Communicated by Ramaswamy H. Sarma
Supplemental Material7 - Supplemental material for Indications and outcome in total elbow arthroplasty: A systematic review
Creators: name: Samdanis, Vasileios
name: Manoharan, Gopikanthan
name: Jordan, Robert W
name: Watts, Adam C
name: Jenkins, Paul
name: Kulkarni, Rohit
name: Thomas, Michael
name: Rangan, Amar
name: Hay, Stuart M
Publisher: name: SAGE Journals
Year: 2019
Subjects: Orthopaedics
Sports Medicine
Surgery

description: Supplemental material, Supplemental Material7 for Indications and outcome in total elbow arthroplasty: A systematic review by Vasileios Samdanis, Gopikanthan Manoharan, Robert W Jordan, Adam C Watts, Paul Jenkins, Rohit Kulkarni, Michael Thomas, Amar Rangan and Stuart M Hay in Shoulder & Elbow
Additional file 1 of Developing a mortality risk prediction model using data of 3663 hospitalized COVID-19 patients: a retrospective cohort study in an Egyptian University Hospital
Creators: name: Kandil, Sahar
name: Tharwat, Ayman I.
name: Mohsen, Sherief M.
name: Eldeeb, Mai
name: Abdallah, Waleed
name: Hilal, Amr
name: Sweed, Hala
name: Mortada, Mohamed
name: Arif, Elham
name: Ahmed, Tarek
name: Elshafie, Ahmed
name: Youssef, Tarek
name: Zaki, Mohamed
name: El-Gendy, Yasmin
name: Ebied, Essam
name: Hamad, Safwat
name: Habil, Ihab
name: Dabbous, Hany
name: El-Said, Amr
name: Mostafa, Yasser
name: Girgis, Samia
name: Mansour, Ossama
name: El-Anwar, Ali
name: Omar, Ashraf
name: Saleh, Ayman
name: El-Meteini, Mahmoud
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Cancer

description: Additional file 1: Supplementary Table 1. Comorbidities: proportions and mortality prediction. Supplementary Table 2. Presenting symptoms/conditions: proportions and mortality prediction. Supplementary Table 3. Biomarkers as mortality predictors. Supplementary Table 4. Details of model parameters: intercept and β coefficients for model components. Predicted mortality probability: equations and example.
Supplemental Material2 - Supplemental material for The Parallel Auditory Brainstem Response
Creators: name: Polonenko, Melissa J.
name: Maddox, Ross K.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental Material2 for The Parallel Auditory Brainstem Response by Melissa J. Polonenko and Ross K. Maddox in Trends in Hearing
AIM818272_Supplemental_material_1 – Supplemental material for Acupuncture in sham device controlled trials may not be as effective as acupuncture in the real world: a preliminary network meta-analysis of studies of acupuncture for hot flashes in menopausal women
Creators: name: Kim, Tae-Hun
name: Lee, Myeong Soo
name: Alraek, Terje
name: Birch, Stephen
Publisher: name: SAGE Journals
Year: 2019
Subjects: Medicine

description: Supplemental material, AIM818272_Supplemental_material_1 for Acupuncture in sham device controlled trials may not be as effective as acupuncture in the real world: a preliminary network meta-analysis of studies of acupuncture for hot flashes in menopausal women by Tae-Hun Kim, Myeong Soo Lee, Terje Alraek and Stephen Birch in Acupuncture in Medicine
AIM818272_Supplemental_material_3 – Supplemental material for Acupuncture in sham device controlled trials may not be as effective as acupuncture in the real world: a preliminary network meta-analysis of studies of acupuncture for hot flashes in menopausal women
Creators: name: Kim, Tae-Hun
name: Lee, Myeong Soo
name: Alraek, Terje
name: Birch, Stephen
Publisher: name: SAGE Journals
Year: 2019
Subjects: Medicine

description: Supplemental material, AIM818272_Supplemental_material_3 for Acupuncture in sham device controlled trials may not be as effective as acupuncture in the real world: a preliminary network meta-analysis of studies of acupuncture for hot flashes in menopausal women by Tae-Hun Kim, Myeong Soo Lee, Terje Alraek and Stephen Birch in Acupuncture in Medicine
Multipolarity and EU Foreign and Security Policy: Divergent Approaches to Conflict and Crisis Response
Creators: name: Dandashly, Assem
name: Dijkstra, Hylke
name: Marafona, Marta
name: Noutcheva, Gergana
name: Paikin, Zachary
Publisher: name: Zenodo
Year: 2021

description: Growing multipolar competition affects the ability of the EU and its member states to formulate and implement common action on crises and conflicts. The effort by the “international community” to ensure global security and peace is weakening due to a divergence in the approaches to crises and conflicts by the major powers, which are often at odds with the EU’s integrated and normative approaches. The increasing involvement of a multitude of major powers and regional players directly affects the EU’s efforts to influence developments in specific regional settings. EU political leverage and/or normative appeal with local actors is eroding and the EU increasingly encounters (state-sponsored) contesters of its policies. At the same time, multipolar competition in crises and conflicts varies considerably across regions and the different major powers play very different roles. Future research should focus on how the EU can engage with different actors across crises and conflicts to mitigate the effects of multipolar competition.
TEACHING THE UZBEK LANGUAGE USING METHODS
Creators: name: Palvonnazarova, Hayatkhan
Publisher: name: Zenodo
Year: 2024

description: In this article, we will consider the most effective methods of teaching the Uzbek language and how they can be used in the classroom. Teaching spelling rules to students based on the cacography method, that is, the method of error justification, the issues of correcting texts containing deliberately introduced errors are discussed.
Additional file 3 of Complete mitochondrial genome of Thuja sutchuenensis and its implications on evolutionary analysis of complex mitogenome architecture in Cupressaceae
Creators: name: Xia, Changying
name: Li, Jingling
name: Zuo, Youwei
name: He, Ping
name: Zhang, Huan
name: Zhang, Xiaoxia
name: Wang, Binru
name: Zhang, Jiabin
name: Yu, Jie
name: Deng, Hongping
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Table S3. 1 General features of seven gymnosperm mitogenomes. Table S3. 2 Primers used in this study.
Evaluation of anticancer activity of Gmelina asiatica leaves, in-vitro and in-silico studies
Creators: name: Ksirri, Rasha
name: Bhanukiran, Kancharla
name: Maity, Swapan
name: Maiti, Pralay
name: Hemalatha, Siva
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Cell Biology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Cervical cancer poses a major threat to women’s health worldwide, constituting the fourth most prevalent cancer among the female population. High-risk variants of human papillomavirus (HPV) with its oncogenic proteins are a necessary cause of cervical cancer. Due to the resistance of cancer cells to the current treatment, there is a need for new medicines with new strategies to treat cervical cancer. Gmelina asiatica Linn. is a medicinal plant with various traditional uses and biological activities. Its anticancer potential against breast cancer and lymphoma has been demonstrated in the literature. In view of this, our study aims to investigate the anticancer activity of Gmelina asiatica leaves against cervical cancer. Various extracts of Gmelina asiatica leaves were prepared by soxhletation and maceration methods. The cytotoxic activity of the extracts was evaluated through in-vitro studies against SiHa cell line using MTT assay and fluorescence imaging. The most potent extract (GAME) phytochemical profile was analysed by UHPLC-HRMS. Further, in-silico studies were performed on its phytoconstituents against E6 oncoprotein, and the DFT studies were conducted on the active component to assess the physicochemical properties. In-vitro studies revealed that methanolic extract (GAME) showed the highest inhibition on the SiHa cell line compared to the other extracts and the control (p < 0.0001). In-silico studies indicated high affinity with stable interaction of the compound 5 (JC5ABDR) at E6 binding sites. This study revealed the importance of Gmelina asiatica plant as a potential source of anticancer molecules with a specific mode of action against cervical cancer. Communicated by Ramaswamy H. Sarma
Additional file 1 of Complete mitochondrial genome of Thuja sutchuenensis and its implications on evolutionary analysis of complex mitogenome architecture in Cupressaceae
Creators: name: Xia, Changying
name: Li, Jingling
name: Zuo, Youwei
name: He, Ping
name: Zhang, Huan
name: Zhang, Xiaoxia
name: Wang, Binru
name: Zhang, Jiabin
name: Yu, Jie
name: Deng, Hongping
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Gel electrophoresis imagefor the PCR products. M, marker; 1-6, the ID of the duplicated biologicalsamples. The expected lengths of each fragment are shown at the bottom of thegel. Figure S2. Sanger sequencing results. Panels A, B, C and D are the alignment of corresponding genomic regions (the first row) with the PCR products (all rows except the first row). A: the connection region 1 between contig 1 and contig 3; B: the connection region 2 between contig 1 and contig 3, C: the connection region between contig 1 and contig 2; D the connection region between contig 2 and contig 3. Figure S3. The histogram of simple sequence repeats (SSRs) identified in the 4 contigs of Thuja sutchuenensis. Figure S4. The histogram of dispersed repeats identified in the 4 contigs of Thuja sutchuenensis. Figure S5. The distribution of long repeats (>500 bp) in the whole mitogenome of Thuja sutchuenensis. Figure S6. The histogram of simple sequence repeats (SSRs) and dispersed repeats identified in the 7 gymnosperm mitogenomes. A and B shows the comparison of SSRs and dispersed repeats among the 7 gymnosperm mitogenomes, respectively. Figure S7. The histogram of long repeats identified in the 7 gymnosperm mitogenomes. Figure S8. Homologous fragments between the chloroplast and mitochondrial genome of Thuja sutchuenensis. The red, blue and green fragments represent homologous fragments with the percent of identity more than 90, more than 80 but less than 90, less than 80, respectively. Figure S9. The distribution of mitochondrial gene clusters in 7 gymnosperms. Figure S10. Heatmap of pairwise dN/dSratios between each pair of sequences in the multigene nucleotide alignment. Figure S11. Distribution diagram of 4 pairs of specific primers.
Vielfalt In Der Professionellen Laufbahn Soziokultureller Animatorinnen Und Animatoren: Zum Einstieg In Alternative Handlungsfelder Der Ska
Creators: name: Sayilir, Salman
Publisher: name: Zenodo
Year: 2014
Subjects: subject: gnd:4721392-9
subject: gnd:4047376-4

description: Gegenstand dieser Arbeit sind Strategien der Fachleute der Soziokulturellen Animation beim Einstieg in ein alternatives Handlungsfeld oder beim Stellenwechsel. Ausserdem interessieren Kompetenzen, Fähigkeiten, Fertigkeiten und Wissen sowie Vor- und Weiterbildungen, die sie benötigen. Daraus ergab sich die Hauptfrage, welche Strategien und Argumente Soziokulturelle Animatorinnen und Animatoren für den Einstieg in alternative Handlungsfelder verwenden und welche Kompetenzen, Fähigkeiten, Fertigkeiten und welches Wissen dafür erforderlich sind. Die Beantwortung der Hauptfrage erfolgte durch eine qualitative Forschung. Mit sechs Fachleuten der Soziokulturellen Animation, die in alternativen Handlungsfeldern tätig sind, wurden episodische Interviews durchgeführt. Die Auswertung zeigte, dass vielfältige Strategien für die Stellensuche eingesetzt werden, wobei die Befragten auch die Gunst der Stunde nutzen, wenn sich eine Gelegenheit bietet, eine interessante Stelle zu erhalten. Strategisch gehen die Befragten ausserdem vor, um ihre mehrschichtigen beruflichen Ziele zu erreichen. Sie nutzen die SKA, um ihren Wunsch, mit Menschen zu arbeiten, zu realisieren. Die Wahl eines alternativen Handlungsfelds erlaubt es ihnen, zusätzliche Interessen wie Sport oder Kunst und Kultur in ihre berufliche Umwelt zu integrieren. Für ihre Arbeit sind laut den Befragten primär die mit der SKA erworbenen Kompetenzen nötig. Für einige Handlungsfelder kommen ausserhalb der SKA erworbene Kompetenzen, Fähigkeiten, Fertigkeiten oder ausserhalb der SKA erworbenes Wissen hinzu. Formalisierte Aus- und Weiterbildungen existieren nur für wenige alternative Handlungsfelder, die Befragten bilden sich deshalb oft individuell weiter.
description: +Code Diss LU: hslusa bask 2014 + Fussnote: Bachelor-Arbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Soziokultur, 2014
Partial syntheses of aromatic amides: their anti-urease potential and docking studies
Creators: name: Onocha, Patricia Akpomedaye
name: Okpala, Ejike Onwudiegwu
name: Ali, Muhammad Shaiq
name: Rahman, Noor
name: Zafar, Humaira
name: Oloyede, Ganiyat Kehinde
name: Nwozo, Sarah Oyenibe
name: Lateef, Mehreen
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: The aromatic amide: N-p-trans-coumaroyltyramine (1) was isolated for the first time from the stem bark of Celtis zenkeri (Ulmaceae). Its four new derivatives (1a–d) and previously reported diacetylated product (1e) have been synthesized and characterized spectroscopically followed by their in vitro screening for anti-urease potential. The diacetylated product (1e) was found to be the most potent inhibitor with an IC50 value of 19.5 ± 0.23 μM compared to thiourea used as standard (21.5 ± 0.47 μM). Furthermore, molecular docking studies were conducted revealing striking interactions of the active compounds with catalytically important residues such as His593, Ala636 and Asp633. Subsequently, the prime MM-GBSA calculations provided the ligand binding and strain energies. The molecular dynamic simulations validated the docked and post-docked complexes where compounds 1b, 1c, 1d and 1e remained stable throughout the simulation. This study provides insight into the N-p-trans-coumaroyltyramine derivatives (1b–e) that can block the substrate entry, thereby inhibiting the urease’s catalytic activity. Hence, these hit compounds can proceed for further pre-clinical studies for drug discovery against urease. Communicated by Ramaswamy H. Sarma
Chrysin inhibits adipogenesis by modulating PPARγ: in silico and in vitro studies
Creators: name: Soumya, Sasikumar Jalajakumari
name: Abhinand, Chandran Sheela
name: Nair, Arya Saseendran
name: Sonu, Priji Sathyan
name: Nair, Govindapillai Mohanadasan
name: Gangaprasad, Appukuttan Nair
name: Nair, Achuthsankar S.
name: Nair, Ananthakrishnan Jayakumaran
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: Adipose tissue is the major storage site of lipids and plays a vital role in energy homeostasis. Adipogenesis is a well-regulated process wherein preadipocytes differentiate into adipocytes. It requires the sequential activation of numerous transcription factors, including peroxisome proliferator activated receptor-γ (PPAR-γ). Phytochemicals have been reported to regulate adipogenesis and flavonoids represent the most researched groups of phytochemicals with regard to their effect on adipogenesis. Chrysin is a naturally occurring flavone and is reported to have anti-inflammatory effects in obese conditions. The present study was aimed to examine the effect of chrysin on adipogenesis. In silico Molecular docking, dynamic simulation studies and in vitro cell-based assays showed that chrysin inhibited adipogenesis by modulating key adipogenic transcription factor PPARγ. Enhanced adipogenesis leads to obesity and targeting adipogenesis is potential in regulating adipose tissue development. So, these investigations may provide important information for designing therapeutic interventions to control adiposity. Communicated by Ramaswamy H. Sarma
Additional file 1 of The self-assessment scale of cognitive complaints in Schizophrenia: validation of the Arabic version among a sample of lebanese patients
Creators: name: Haddad, Chadia
name: Sacre, Hala
name: Abboche, Elie
name: Salameh, Pascale
name: Calvet, Benjamin
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Mental Health
subject: Hematology

description: Supplementary Table 1: Factor analysis using the maximum likelihood method with Promax Rotation
Deciphering mitogen activated protein kinase pathway activated during insect attack in Nicotiana attenuata
Creators: name: Yajnik, Kalpesh Nath
name: Gupta, Shradheya R. R.
name: Taneja, Mansi
name: Singh, Indrakant K.
name: Singh, Archana
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology

description: Plant yields are compromised due to abiotic and biotic stresses. A crucial biotic stress instigated by insect attack, is a major concern that limits crop production. To overcome the deleterious effect of herbivory, pesticides are used but long-term usage of pesticides can be harmful to the environment and human health. Understanding the plants’ inherent defense mechanism by interpreting the interaction pattern of defense-related proteins and signalling components and manipulating them to strengthen defense status, is one of the alternative approaches of green biotechnology. During insect attack, host plants initiate innumerable signalling pathways to activate defense response; Mitogen Activated Protein Kinase (MAPK) Pathway is a crucial component of signalling pathway that regulate the expression of downstream defense-related genes. MAPK pathway has three components: MAPKKK, MAPKK and MAPK. Earlier studies have shown participation of SIPK and WIPK (MAPKs) as well as MEK2 (MAPKK) during insect infestation and its association with plant defense. However, information on the third component and elucidation of the complete MAPK pathway are still elusive. Therefore, this study aims to identify the unknown component and decipher MAPK pathway in Nicotiana attenuata involved in plant defense against herbivory by identifying herbivory-inducible MAPKKKs and and their interaction with known partners of the MAPK pathway by docking and MD simulation. The possible pathway was predicted to be MAPKKK Na12134/Na04522-MEK2-SIPK/WIPK. Further, validation of the above interaction by in vitro and in vivo methods is highly recommended. Communicated by Ramaswamy H. Sarma
sj-pdf-1-css-10.1177_2470547020917623 - Supplemental material for Processing of Positive Visual Stimuli Before and After Symptoms Provocation in Posttraumatic Stress Disorder – A Functional Magnetic Resonance Imaging Study of Trauma-Affected Male Refugees
Creators: name: Uldall, Sigurd W.
name: Madsen, Kristoffer H.
name: Siebner, Hartwig R.
name: Lanius, Ruth
name: Frewen, Paul
name: Fischer, Elvira
name: Madsen, Camilla G.
name: Anne-Mette Leffers
name: Rostrup, Egill
name: Carlsson, Jessica L.
name: Ayna B. Nejad
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-css-10.1177_2470547020917623 for Processing of Positive Visual Stimuli Before and After Symptoms Provocation in Posttraumatic Stress Disorder – A Functional Magnetic Resonance Imaging Study of Trauma-Affected Male Refugees by Sigurd W. Uldall, Kristoffer H. Madsen, Hartwig R. Siebner, Ruth Lanius, Paul Frewen, Elvira Fischer, Camilla G. Madsen, Anne-Mette Leffers, Egill Rostrup, Jessica L. Carlsson and Ayna B. Nejad in Chronic Stress
Feb_24Clean__Frailty__Supplementarymaterials_1 – Supplemental material for The Burden of Frailty on Mood, Cognition, Quality of Life, and Level of Independence in Patients on Hemodialysis: Regina Hemodialysis Frailty Study
Creators: name: Jafari, Maryam
name: Kaval Kour
name: Giebel, Shelley
name: Idunnu Omisore
name: Bhanu Prasad
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental material, Feb_24Clean__Frailty__Supplementarymaterials_1 for The Burden of Frailty on Mood, Cognition, Quality of Life, and Level of Independence in Patients on Hemodialysis: Regina Hemodialysis Frailty Study by Maryam Jafari, Kaval Kour, Shelley Giebel, Idunnu Omisore and Bhanu Prasad in Canadian Journal of Kidney Health and Disease