cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Racismo no futebol: o que a linguagem do discurso midiático pode nos dizer?
Creators: name: Silva Pimenta, Izadora
Publisher: name: Université Libre de Bruxelles
Year: 2024

description: O presente artigo tem como objetivo analisar os Julgamentos (Martin e White, 2005) presentes no discurso midiático a respeito de um caso de racismo sofrido por um jogador de futebol em 2014. A análise foi feita a partir do fragmento de um corpus coletado em minha pesquisa de mestrado (Pimenta, 2019), compilado com a plataforma Sketch Engine a partir de 65 artigos de hard news sobre o tema, publicados de forma online no Brasil, totalizando 21.387 formas, 1.014 sentenças e 25.127 palavras. Para os trechos analisados neste artigo, considera-se apenas os trechos das notícias nos quais a voz do repórter está sendo utilizada em primeiro plano. A análise é realizada a partir da Linguística Sistêmico-Funcional (Halliday e Matthiessen, 2014) e do Sistema de Avaliatividade (Martin e White, 2005), a partir dos quais a linguagem é visualizada como um sistema sociossemiótico, ou seja, entende-se que a comunicação se dá por um sistema, sendo ele repleto de significados de cunhos sociais e culturais. O trabalho também se baseia na hipótese de que as hard news nunca são neutras (White, 2003) e, portanto, passíveis da presença de significados avaliativos ao longo do texto. Para compreender o contexto no qual as notícias estão sendo relatadas, há ainda uma compreensão inicial sobre alguns preceitos das relações raciais no Brasil e no futebol. Os resultados mostram que a linguagem utilizada pelo discurso midiático opera como fator de reforço para padrões de representação sobre o racismo no futebol e seus aspectos presentes na sociedade brasileira. Uma vez em que o racismo é base para as formas de desigualdade e violência dessa sociedade (Almeida, 2019), é possível observar que a presença deste na estrutura se mostra visível na linguagem em uso. Os dados obtidos nesta pesquisa oferecem, ainda, um desenho para uma metodologia de análise de aspectos sociológicos do esporte e do racismo como ideologia vigente por meio da linguagem intrínseca.
Additional file 3 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
Creators: name: Ayyagari, Vijaya Sai
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 3: Supplementary Table 3. Conserved regions of gene ‘S’ used for the design of siRNAs.
Additional file 4 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
Creators: name: Ayyagari, Vijaya Sai
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 4: Supplementary Table 4. List of siRNAs predicted by RNAxs for various conserved regions of ‘M’ gene.
In silico analysis of metal coordination geometry in arsenic, beryllium, and lead bound structures
Creators: name: R. Jesu Jaya Sudan
name: C. Sudandiradoss
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Metal toxicity is a potential hazard to health and toxic effects of metals have been implicated in many diseases. Understanding the interaction of toxic metals becomes vital to prevent hazards following its association in living systems. Coordination chemistry helps in predicting the metal environments like coordinating residues, coordination space, metal coordination geometry, etc. Our work aimed at predicting the coordination of toxic metals arsenic, lead, and beryllium. In this work, we analyzed coordination for each metal from a set of arsenic, beryllium and lead bound structures which were retrieved from the Protein Data Bank. The structures were validated using B-factor and occupancy of the coordinating residues towards the metals. Coordination patterns such as chelate residues, chelate length, geometry, coordination number and structural architecture were predicted. Coordination geometry of the metals was exposed beyond the coordination space with their coordination number ranging from 2 to 11. Analysis of metal environment revealed the acidic amino acids aspartic acid, glutamic acid, and the basic amino acids lysine, histidine, and cysteine to be predominant in coordinating with the metals. Chelate patterns like DDVMITAK, DWNVTVK, ESGKNSS for beryllium, CCCSK, DSDWD for lead and FLICVI and LKHHKEE for arsenic were predicted to be common through extended coordination space. The distinct molecular geometries such as pentagonal bipyramid and square planar were observed only in lead bound structures but not in beryllium and arsenic bound structures. Beryllium had a larger influence than arsenic and lead, based on conformational changes owing to the presence of the metals. Our coordination study puts forth several propositions based on the metal environment that would help in designing chelation strategies.
Additional file 5 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
Creators: name: Ayyagari, Vijaya Sai
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 5: Supplementary Table 5. List of siRNAs predicted by RNAxs for various conserved regions of ‘N’ gene.
Additional file 6 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
Creators: name: Ayyagari, Vijaya Sai
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 6: Supplementary Table 6. List of siRNAs predicted by RNAxs for various conserved regions of ‘S’ gene.
Additional file 7 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
Creators: name: Ayyagari, Vijaya Sai
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 7: Supplementary Table 7. List of siRNAs predicted by siDirect for various conserved regions of the M gene.
Challenges in practice: using molecular biology as a lens
Creators: name: Hendy, Jessica
Publisher: name: Zenodo
Year: 2020
Subjects: SSHOC
E-rihs
SEADDA
E-rihs UK
SEADDA COST Action
Heritage
Digital Heritage
Archaeology
Digital Archaeology
Molecular biology
Heritage data
Data sharing
Biomolecular analysis

description: Challenges in practice: using molecular biology as a lens, presented by Jessica Hendy (Department of Archaeology, University of York) at the webinar "Use and Re-use of Scientific Data in Archaeology and Heritage", co-organised by SSHOC, E-RIHS UK and SEADDA on the 2nd of April 2020.
Additional file 8 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
Creators: name: Ayyagari, Vijaya Sai
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 8: Supplementary Table 8. List of siRNAs predicted by siDirect for various conserved regions of the ‘N’ gene.
Teoria krytyczna szkoły frankfurckiej jako krytyka kultury masowej
Creators: name: Hylewski, Marcin
name: Burdzik, Tomasz
Publisher: name: figshare
Year: 2014
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Anthropology

description: Publication name Hylewski, M., i Burdzik, T. (2014). Teoria krytyczna szkoły frankfurckiej jako krytyka kultury masowej. Kultura-Historia-Globalizacja, (15), 115–137. doi:10.6084/m9.figshare.1050567 Abstrakt Celem artykułu jest przedstawienie krytyki kultury masowej w ujęciu szkoły frankfurckiej. Autorzy dowodzą, iż teoria krytyczna stanowi specyficzną interpretację filozofii marksistowskiej, definiującą na nowo niektóre społeczne oraz polityczne elementy takie jak: produkcja, dystrybucja, fetyszyzacja, konsumpcja oraz wskazuje miejsce i rolę przemysłu kulturowego w powiązaniu z kulturą globalną. W zakończeniu podkreśla się, że koncepcje szkoły frankfurckiej są stale obecne w naukach społecznych oraz uwzględniane przez badaczy. Słowa kluczowe: szkoła frankfurcka, teoria krytyczna, kultura popularna, przemysł kulturowy Abstract The aim of this paper is to present the Frankfurt School’s critique of mass culture. The authors particularly seek to demonstrate that critical theory provides a specific interpretation of Marxist philosophy, reinterprets some of its central economic and political notions such as production, distribution, fetishization, consumption and also attempts to illuminate the place and the role of culture industry within global culture. As a conclusion it is argued that the Frankfurt School’s approach, while it is still useful to social science programs, tends to be overlooked by social theorists. Keywords: Frankfurt School, critical theory, popular culture, culture industry
Additional file 9 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
Creators: name: Ayyagari, Vijaya Sai
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 9: Supplementary Table 9. List of siRNAs predicted by siDirect for various conserved regions of the ‘S’ gene.
Additional file 2 of Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling
Creators: name: Caputo, Luca
name: Granados, Alice
name: Lenzi, Jessica
name: Rosa, Alessandro
name: Ait-Si-Ali, Slimane
name: Puri, Pier Lorenzo
name: Albini, Sonia
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Marine Biology

description: Additional file 2: Figure S2. Validation of the exacerbated TGFβ response in DMD iPSC ex45del- derived myotubes.
Additional file 3 of Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling
Creators: name: Caputo, Luca
name: Granados, Alice
name: Lenzi, Jessica
name: Rosa, Alessandro
name: Ait-Si-Ali, Slimane
name: Puri, Pier Lorenzo
name: Albini, Sonia
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Marine Biology

description: Additional file 3: Figure S3. Optimization of parameters and antibodies used in HCS.
Additional file 1 of Sex-specific differences in the efficacy of traditional low frequency versus high frequency spinal cord stimulation for chronic pain
Creators: name: Conic, Rosalynn R. Z.
name: Caylor, Jacob
name: Cui, Christina L.
name: Reyes, Zabrina
name: Nelson, Eric
name: Yin, Sopyda
name: Lerman, Imanuel
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1.
Facile and Simple Synthesis of N-Alkyl and N-Aryl 2-Benzazepines by Nucleophilic Heteroannulation
Creators: name: A. K. Srinivasan
name: K. Rajashekar
name: B. Shyamapada
name: U. K. Syam Kumar
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Molecular Biology
Cell Biology
Biochemistry

description: An efficient and practical synthesis of N-alkyl and N-aryl 2-benzazepine has been developed. The key steps involved in the synthesis were palladium-mediated Heck reaction followed by aza heterocyclic ring construction by nucleophilic heteroannulation. This four-step sequence synthetic protocol gave moderate to good yields for a wide range of substrates. Subsequently, functionalization of the synthesized compound was carried out under Heck and Suzuki reaction conditions.
Base-Mediated Biginelli-Like Reaction Ignited by Aromatic Isocyanate: A Facile One-Pot Synthesis of N4-Aryl-5-carboxyl-6-methyl Cytimidine Derivatives
Creators: name: Chengyuan Liang
name: Huihui Song
name: Hailong Jiang
name: Qizheng Yao
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: The new three-component Biginelli reaction of aromatic isocyanate, ethyl acetoacetate, and substituted urea (or thiourea as well as guanidine) is described for the first time. In this reaction, N4-aryl-5-carboxyl-6-methyl cytimidine derivatives were obtained in moderate to excellent yields by employing DBU as a highly effective catalyst. This methodology provides several advantages such as good functional group tolerance, excellent yields, atom efficiency, and experimental simplicity.
Engineered multifunctional nanomaterials for multimodal imaging of retinoblastoma cells in vitro
Creators: name: Jaidev, Leela Raghava
name: Dhiraj Vasanth Bhavsar
name: Sharma, Uma
name: Naranamanglam R. Jagannathan
name: Krishnan, Uma Maheswari
name: Swaminathan Sethuraman
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: Multifunctional nanoparticles are next generation materials that can be simultaneously used for imaging, diagnosis, and delivery of drugs. However, materials intended for cancer diagnosis need to be investigated for its cell uptake, toxicity, and effectiveness. In the current work, we have synthesized fluorescent iron oxide nanoparticles and evaluated its efficacy against retinoblastoma cell imaging. The iron oxide nanoparticles were synthesized and stabilized using oleic acid. Sulforhodamine B was adsorbed onto albumin over the oleic acid-capped iron oxide nanoparticles. Our results demonstrated good cell uptake in a time-dependent manner and nanoparticles were found to localize in the cytosol. Further, the nanoparticles exhibited excellent negative contrast in magnetic resonance imaging (MRI) experiments and with no cytoxicity (5–100 μg/mL iron oxide nanoparticles) to both normal as well as cancer cells demonstrating its biocompatibility. Thus, this novel material integrates the ability to image tissues with high sensitivity by MRI and specifically visualize Y79 retinoblastoma cells by fluorescence imaging with no toxicity.
Ferramenta da Terapia de Aceitação e Compromisso (ACT): Exercícios de Reconhecimento de Pequenas Conquistas
Creators: name: Brandl, Edenilson
Publisher: name: Zenodo
Year: 2024
Subjects: Ferramenta da Terapia de Aceitação e Compromisso (ACT)
Exercícios de Reconhecimento de Pequenas Conquistas
Terapia de Aceitação e Compromisso (ACT)
Enciclopédia da Conscienciologia

description: Definologia: Os exercícios de reconhecimento de pequenas conquistas são estratégias terapêuticas utilizadas na Terapia de Aceitação e Compromisso (ACT) que visam promover a consciência e a valorização de progressos e realizações consideradas significativas, por menores que sejam, no processo de mudança e autoaperfeiçoamento do indivíduo.
Additional file 1 of Feasibility and usability of GPS data in exploring associations between training load and running-related knee injuries in recreational runners
Creators: name: Cloosterman, Kyra L. A.
name: Fokkema, Tryntsje
name: de Vos, Robert-Jan
name: van Oeveren, Ben
name: Bierma-Zeinstra, Sita M. A.
name: van Middelkoop, Marienke
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Additional file 1. Supplementary material.
Additional file 1 of Protective effect of the Impella on the left ventricular function after acute broad anterior wall ST elevation myocardial infarctions with cardiogenic shock: cardiovascular magnetic resonance imaging strain analysis
Creators: name: Fukamachi, Daisuke
name: Yamada, Akimasa
name: Ohgaku, Akihito
name: Koyama, Yutaka
name: Fujito, Hidesato
name: Arai, Riku
name: Ebuchi, Yasunari
name: Migita, Suguru
name: Morikawa, Tomoyuki
name: Monden, Masaki
name: Takei, Norio
name: Tamaki, Takehiro
name: Kojima, Keisuke
name: Akutsu, Naotaka
name: Murata, Nobuhiro
name: Saito, Yuki
name: Kitano, Daisuke
name: Sudo, Mitsumasa
name: Okumura, Yasuo
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1. Baseline characteristics and CMRI strain parameters between the Impella, non-Impella with cardiogenic shock, and non-Impella without cardiogenic shock groups.
Teoria krytyczna szkoły frankfurckiej jako krytyka kultury masowej
Creators: name: Hylewski, Marcin
name: Burdzik, Tomasz
Publisher: name: figshare
Year: 2014
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Anthropology

description: Publication name Hylewski, M., i Burdzik, T. (2014). Teoria krytyczna szkoły frankfurckiej jako krytyka kultury masowej. Kultura-Historia-Globalizacja, (15), 115–137. doi:10.6084/m9.figshare.1050567 Hylewski, M., i Burdzik, T. (2014). Teoria krytyczna szkoły frankfurckiej jako krytyka kultury masowej. Kultura-Historia-Globalizacja, (15), 115–137. Pobrano z http://www.khg.uni.wroc.pl/files/8_KHG_15_hylewski_t.pdf Abstrakt Celem artykułu jest przedstawienie krytyki kultury masowej w ujęciu szkoły frankfurckiej. Autorzy dowodzą, iż teoria krytyczna stanowi specyficzną interpretację filozofii marksistowskiej, definiującą na nowo niektóre społeczne oraz polityczne elementy takie jak: produkcja, dystrybucja, fetyszyzacja, konsumpcja oraz wskazuje miejsce i rolę przemysłu kulturowego w powiązaniu z kulturą globalną. W zakończeniu podkreśla się, że koncepcje szkoły frankfurckiej są stale obecne w naukach społecznych oraz uwzględniane przez badaczy. Słowa kluczowe: szkoła frankfurcka, teoria krytyczna, kultura popularna, przemysł kulturowy Abstract The aim of this paper is to present the Frankfurt School’s critique of mass culture. The authors particularly seek to demonstrate that critical theory provides a specific interpretation of Marxist philosophy, reinterprets some of its central economic and political notions such as production, distribution, fetishization, consumption and also attempts to illuminate the place and the role of culture industry within global culture. As a conclusion it is argued that the Frankfurt School’s approach, while it is still useful to social science programs, tends to be overlooked by social theorists. Keywords: Frankfurt School, critical theory, popular culture, culture industry
Additional file 1 of Probiotic in the prevention of ventilator-associated pneumonia in critically ill patients: evidence from meta-analysis and trial sequential analysis of randomized clinical trials
Creators: name: Sun, Yue-chen
name: Wang, Chen-yi
name: Wang, Hai-li
name: Yuan, Yao
name: Lu, Jian-hong
name: Zhong, Lei
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1. Appendix 1: The PRISMA guidelines
A Facile and Simple Synthesis of N-Alkyl and N-Aryl 2-Benzazepines by Nucleophilic Heteroannulation
Creators: name: A. K. Srinivasan
name: K. Rajashekar
name: B. Shyamapada
name: U. K. Syam Kumar
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Molecular Biology
Cell Biology
Biochemistry

description: An efficient and practical synthesis of N-alkyl and N-aryl 2-benzazepine has been developed. The key steps involved in the synthesis were palladium mediated Heck reaction followed by aza heterocyclic ring construction by nucleophilic heteroannulation. This four step sequence synthetic protocol gave moderate to good yield for a wide range of substrates. Subsequently, functionalization of the synthesized compound was carried out under Heck and Suzuki reaction conditions.
Computational Thinking im Fach NMG. Explorative Studie zur Konzeption von unplugged Computational-Thinking-Aufgaben für den NMG-Unterricht der 5. und 6. Primarstufe
Creators: name: Welling, Alexander
Publisher: name: Zenodo
Year: 2024

description: Für eine optimale Interaktion mit Computern, müssen Menschen in der Lage sein, die Probleme der realen Welt so zu formulieren, dass sie von einer Maschine (oder einem Menschen) gelöst werden können. Diese Kompetenz, welche unter dem Begriff Computational Thinking (CT) bekannt ist, wird bereits in der Regelschule in zunehmendem Masse gefördert. Diesbezüglich propagieren diverse Forschende, CT in naturwissenschaftliche Fächer zu integrieren. 

Dementsprechend verfolgt diese Masterarbeit das Ziel, literaturgestützte und praxisnahe unplugged CT-Aufgaben für das Unterrichtsfach Natur, Mensch, Gesellschaft (NMG) zu erstellen. 

Dazu wurden sechs qualitative Leitfaden-Interviews mit Primarlehrerinnen und NMG-Fachdidaktikern geführt und mittels einer qualitativen Inhaltsanalyse bearbeitet. 

Aus den Ergebnissen ging hervor, dass die Befragten über ein oberflächliches Präkonzept bezüglich CT verfügten, wobei sie CT-ähnliche Problemlösestrategien aus ihrem Alltag kannten und in ihrer Berufspraxis eher unbewusst anwandten. Des Weiteren zählten die Interviewten insgesamt 40 Anwendungsbeispiele für die Integration von CT im Fach NMG auf. Diese können 21 NMG-Kompetenzen zugeschrieben werden, die auf alle zwölf NMG-Kompetenzbereiche verteilt sind. 

Basierend auf den Umsetzungsvorschlägen sind acht prototypische unplugged CT-Aufgaben für das Fach NMG entstanden. 

Die Erkenntnisse aus dieser Masterarbeit lassen zweierlei Implikationen zu. Einerseits ähnelt CT anderen Problemlösestrategien, die im Alltag eines jeden Menschen genutzt werden. Die Aus- und Weiterbildung im Bereich CT sollte Lehrpersonen demnach aufzeigen, welche Bedeutung diese Kompetenz spezifisch in der Informatik hat. Andererseits weisen die Forschungsergebnisse darauf hin, dass CT in subtiler Weise in den Unterricht der Regelschule integriert werden kann, da es Überschneidungen mit den Denk-, Arbeits- und Handlungsweisen des Fachs NMG und den überfachlichen Kompetenzen des Lehrplans 21 aufweist.
Additional file 2 of Probiotic in the prevention of ventilator-associated pneumonia in critically ill patients: evidence from meta-analysis and trial sequential analysis of randomized clinical trials
Creators: name: Sun, Yue-chen
name: Wang, Chen-yi
name: Wang, Hai-li
name: Yuan, Yao
name: Lu, Jian-hong
name: Zhong, Lei
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 2. Appendix 2: The PICO framework, search strategy and search results
Base-Mediated Biginelli-Like Reaction Ignited by Aromatic Isocyanate: A Facile One-Pot Synthesis of N4-Aryl-5-Carboxyl-6-Methyl Cytimidine Derivatives
Creators: name: Chengyuan Liang
name: Huihui Song
name: Hailong Jiang
name: Qizheng Yao
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The new three-component Biginelli reaction of aromatic isocyanate, ethyl acetoacetate, and substituted urea (or thiourea as well as guanidine) was described for the first time. In this reaction, N4-aryl-5-carboxyl-6-methyl cytimidine derivatives were obtained in moderate to excellent yield employing DBU as a highly effective catalyst. This methodology provides several advantages such as good functional group tolerance, high yields, atom efficiency and experimental simplicity.
Engineered multifunctional nanomaterials for multimodal imaging of retinoblastoma cells in vitro
Creators: name: Jaidev, Leela Raghava
name: Dhiraj Vasanth Bhavsar
name: Sharma, Uma
name: Naranamanglam R. Jagannathan
name: Krishnan, Uma Maheswari
name: Swaminathan Sethuraman
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Multifunctional nanoparticles are next generation materials that can be simultaneously used for imaging, diagnosis, and delivery of drugs. However, materials intended for cancer diagnosis need to be investigated for its cell uptake, toxicity, and effectiveness. In the current work, we have synthesized fluorescent iron oxide nanoparticles and evaluated its efficacy against retinoblastoma cell imaging. The iron oxide nanoparticles were synthesized and stabilized using oleic acid. Sulforhodamine B was adsorbed onto albumin over the oleic acid-capped iron oxide nanoparticles. Our results demonstrated good cell uptake in a time-dependent manner and nanoparticles were found to localize in the cytosol. Further, the nanoparticles exhibited excellent negative contrast in magnetic resonance imaging (MRI) experiments and with no cytoxicity (5–100 μg/mL iron oxide nanoparticles) to both normal as well as cancer cells demonstrating its biocompatibility. Thus, this novel material integrates the ability to image tissues with high sensitivity by MRI and specifically visualize Y79 retinoblastoma cells by fluorescence imaging with no toxicity.
A Review of Mass Spectrometry as an Important Analytical Tool for Structural Elucidation of Biological Products
Creators: name: Ajayi, Oluwaseun
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 340101
subject: Analytical spectrometry
classificationCode: 340403
subject: Characterisation of biological macromolecules
classificationCode: 340407
subject: Proteins and peptides
classificationCode: 340405
subject: Glycoconjugates
classificationCode: 340401
subject: Biologically active molecules
classificationCode: 310107
subject: Glycobiology
classificationCode: 310109
subject: Proteomics and intermolecular interactions (excl. medical proteomics)

description: Advancements on Mass Spectrometry applications
Additional file 3 of Probiotic in the prevention of ventilator-associated pneumonia in critically ill patients: evidence from meta-analysis and trial sequential analysis of randomized clinical trials
Creators: name: Sun, Yue-chen
name: Wang, Chen-yi
name: Wang, Hai-li
name: Yuan, Yao
name: Lu, Jian-hong
name: Zhong, Lei
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 3. Appendix 3: The results of sensitivity analysis, reporting bias, trial sequential analysis and forest plots
RIS for Students Data Management Plan Rubric
Creators: name: Marcoux, Katherine
name: de Laat, Stijn
name: Jansen, Daphne
name: Lamers, Didi
name: Slouwerhof, Inge
name: van der Burgt, Henry
Publisher: name: Zenodo
Year: 2023
Subjects: RDM
research data
data management
research data management
data organisation
data management plan
students

description: This rubric is meant to guide supervisors when they are evaluating student DMPs. The rubric is based on RIS for Students' “Students’ RU Format - General” v2.1 template from September 2023, which is available to students and staff at Radboud University. More information on how to fill out a DMP using RIS for Students can be found here.
RIS for Students Data Management Plan Rubric
Creators: name: Marcoux, Katherine
name: de Laat, Stijn
name: Jansen, Daphne
name: Lamers, Didi
name: Slouwerhof, Inge
name: van der Burgt, Henry
Publisher: name: Zenodo
Year: 2024
Subjects: RDM
research data
data management
research data management
data organisation
data management plan
students

description: This rubric is meant to guide supervisors when they are evaluating student DMPs. The rubric is based on RIS for Students' “Students’ RU Format - General” v2.2 template from November 2023, which is available to students and staff at Radboud University. More information on how to fill out a DMP using RIS for Students can be found here.
Reversal Diastereoselectivity Between the Organomagnesium and Organolithium Reagents on Chiral N-Tert-Butylsulfinylaldimines for the Preparation of Chiral Amines
Creators: name: Chinnapillai Rajendiran
name: Periyandi Nagarajan
name: A. Naidu
name: P. K. Dubey
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorized

description: The asymmetric synthesis of both the enantiomer of chiral amines from the single chiral source of N-tert-butylsulfinylaldimines (3) by simply changing the organometallic reagents through diastereoselective addition. An efficient enantioselective synthesis of chiral amines including (S)-3-methyl-1-(2-piperidin-1-yl-phenyl)butyl amine (6a), a key intermediate to prepare antidiabetic drug repaglinide (1), is reported.
Additional file 4 of Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling
Creators: name: Caputo, Luca
name: Granados, Alice
name: Lenzi, Jessica
name: Rosa, Alessandro
name: Ait-Si-Ali, Slimane
name: Puri, Pier Lorenzo
name: Albini, Sonia
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Marine Biology

description: Additional file 4: Figure S4. Pharmacological inhibition of SMAD signaling.
Additional file 9 of Nutritional and genetic variation in a core set of Ethiopian Tef (Eragrostis tef) varieties
Creators: name: Ereful, Nelzo C.
name: Jones, Huw
name: Fradgley, Nick
name: Boyd, Lesley
name: Cherie, Hirut Assaye
name: Milner, Matthew J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 9: Fig. 1. Significant correlations between the elemental concentrations in 24 teff flours. Size of the circle represents the significance level, with the larger the circle the lower the p value. All circles represent a p value less than 0.05. Scale on the left is the range of correlations (r). Fig. 2. Phylogenetic tree showing the relationship between the five teff homologues of the rice F3’H gene Os10t0320100–01.
Best practice and tools for use and re-use
Creators: name: Orr, Scott Allan
Publisher: name: Zenodo
Year: 2020
Subjects: SSHOC
E-rihs
E-Rihs UK
SEADDA
SEADDA COST Action
Heritage
Heritage Data
Heritage Data Science
Heritage Science
Sustainable Heritage
Archaeology
Digital Archaeology
Digital Heritage
Data re-use
Data stewardship

description: Best practice and tools for use and re-use, presented by Scott Allan Orr (The Bartlett Institute for Sustainable Heritage - UCL) at the webinar "Use and Re-use of Scientific Data in Archaeology and Heritage", co-organised by SSHOC, E-RIHS UK and SEADDA on the 2nd of April 2020.
Asymmetric Total Synthesis of Stagonolide F
Creators: name: B. Chinnababu
name: S. Purushotham Reddy
name: K. Suresh Babu
name: Y. Venkateswarlu
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Biochemistry
subject: Biophysics

description: A highly convergent stereoselective total synthesis of stagonolide F is described starting from commercially available 5-hexen 1-ol using asymmetric dihydroxylation, Jacobsen's hydrolytic kinetic resolution (HKR), regioselective epoxide ring opening with vinyl Grignard reaction, esterification, and ring-closing metathesis (RCM) as key steps.
Base-Mediated Biginelli-Like Reaction Ignited by Aromatic Isocyanate: A Facile One-Pot Synthesis of N4-Aryl-5-carboxyl-6-methyl Cytimidine Derivatives
Creators: name: Chengyuan Liang
name: Huihui Song
name: Hailong Jiang
name: Qizheng Yao
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The new three-component Biginelli reaction of aromatic isocyanate, ethyl acetoacetate, and substituted urea (or thiourea as well as guanidine) is described for the first time. In this reaction, N4-aryl-5-carboxyl-6-methyl cytimidine derivatives were obtained in moderate to excellent yields by employing DBU as a highly effective catalyst. This methodology provides several advantages such as good functional group tolerance, excellent yields, atom efficiency, and experimental simplicity.
COMPUTATIONAL STUDY OF THE INTERNAL KINK MODE EVOLUTION AND ASSOCIATED MAGNETIC RECONNECTION PHENOMENA
Creators: name: Lukin, Vyacheslav S.
Publisher: name: Zenodo
Year: 2008
Subjects: plasma physics
magnetic reconnection
magnetohydrodynamics
fusion
computational modeling

description: Numerical study of plasma relaxation and self-organization in two-dimensional incompressible magnetohydrodynamic (MHD) systems is presented. A large semiperiodic tearing unstable reversed magnetic field configuration in flat Cartesian geometry and a driven tokamak-like kink-unstable screw pinch in helical geometry are considered. Special emphasis is made on the coupling between global and local scales by way of magnetic reconnection. The influence of the global system’s size and geometry on the magnetic reconnection phenomenon and associated current sheet dynamics are evaluated in different collisionality regimes. Questions of plasmoid formation by way of current sheet break-up and onset of fast reconnection in a semi-collisional regime are investigated. Visco-resistive, electron and Hall MHD plasma fluid models are employed in the study. In helical geometry, application of Ohmic current drive to the periodic screw-pinch with large axial magnetic field and hollow resistivity profile are shown to result in “sawtooth-like” limit cycle behavior which is independent of the exact initial conditions. Incomplete reconnection sawteeth, maintaining the value of safety factor q in the central plasma region below unity throughout the cycle, are demonstrated for the first time in numerical simulations. Sensitivity of sawtooth characteristics to a number of plasma parameters is evaluated. The initial value problems described above are solved with an adaptive fully implicit parallel macroscopic modeling code SEL, which is capable of evolving a large range of extended MHD equations. The structure, key features, and thorough testing of the code are described in detail.
PSIXOLOGIK HOLATLARGA TUSHISHNI OLDINGI OLISH
Creators: name: Sadullayeva Gulchiroy Maxmud  kizi Buxoro viloyati Gijduvon tumani 10- maktab amaliyotchi psixologi
Publisher: name: Zenodo
Year: 2024

description: Ushbu  maqolada psixologik holat va unig oldini olish choralari, stressni keltirib chiqaruvchi omillar, stress natijasida insonda uchraydigan psixologik o‘zgarishlar, stress bilan bevosita bog‘liq bo‘lgan va stressning natijasi bo‘lgan eng keng tarqalgan kasalliklar haqida fikrlar yuritilgan.

Kalit so‘zlar: psixologik holat, stress, fiziologik stress, achchiq kayfiyat, oshqozon yarasi, his-tuyg‘u, psixolog, psixiatr
Reversal Diastereosectivity Between the Organomagnesium and Organo- Lithium Reagents on Chiral N-tert-Butylsulfinylaldimines for the Preparation of Chiral Amines
Creators: name: Chinnapillai Rajendiran
name: Periyandi Nagarajan
name: A. Naidu
name: P. K. Dubey
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The asymmetric synthesis of both the enantiomer of chiral amines from the single chiral source of N-tert-butylsulfinylaldimines(3) by simply changing the organometallic reagents through diastereoselective addition. An efficient enantioselective synthesis of chiral amines including (S)-3-methyl-1-(2-piperidin-1-yl- phenyl)butyl amine(6a) a key intermediate to prepare antidiabetic drug Repaglinide(1) is reported.
An Effective Tea Leaf Classifier Using Faster R-CNN with Real-Time Object.pdf
Creators: name: Perera, Lahiru
Publisher: name: figshare
Year: 2022
Subjects: Computer Engineering

description: Tea is one of the most significant beverages preferred all across the world and is undoubtedly a huge cash crop in the world, grown in climatically restricted geographic areas. The best Tea is prepared from the best Tea leaves grown under optimum conditions. Since the quality and the condition of the tea leaves is so vital in the Tea Industry as a beverage, the classification of eligible tea leaves that should be plucked has become an active area of research as the Tea Cultivation industry itself is facing threats due to lack of labor. This paper is mainly focused on classifying the 21-days old tender tea shoots from the younger buds. Images of the Tea Leaves are fed to the classifier from a mobile camera. This proposed approach consists of three phases such as preprocessing, classification to process the fed image and predictions through real-time Object Detection. The captured images are preprocessed using the Grabcut-image segmentation technique in order to introduce masking to support the followed labeling process. The Faster R-CNN model is trained with the labeled images to classify the leaves into 2 - classes, ready to be plucked and not-ready to be plucked. The trained model is experimented with video footage to provide prediction through real-time Object Detection. The experimental results of the tested tea leaf images proved that the proposed method classifies the tea leaves with an IoU of 0.670.
Expectations on Log Anomaly Detection
Creators: name: Anonymity
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 401003
subject: Engineering practice

description: The main objectives of this survey are to investigate: (1) whether practitioners have used log monitoring tools for log anomaly detection and (2) practitioners' expectations for automated log anomaly detection tools. Your insights will greatly contribute to our understanding of log anomaly detection techniques and assist us in developing useful log anomaly detection tools for you and other practitioners.
Docking-based 3D-QSAR study of pyridyl aminothiazole derivatives as checkpoint kinase 1 inhibitors
Creators: name: A. Balupuri
name: P.K. Balasubramanian
name: C.G. Gadhe
name: S.J. Cho
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Information and Computing Sciences
Biological Sciences
Chemistry
Biochemistry

description: Checkpoint kinase 1 (Chk1) is a promising target for the design of novel anticancer agents. In the present work, molecular docking simulations and three-dimensional quantitative structure–activity relationship (3D-QSAR) studies were performed on pyridyl aminothiazole derivatives as Chk1 inhibitors. AutoDock was used to determine the probable binding conformations of all the compounds inside the active site of Chk1. Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) models were developed based on the docking conformations and alignments. The CoMFA model produced statistically significant results with a cross-validated correlation coefficient (q2) of 0.608 and a coefficient of determination (r2) of 0.972. The reliable CoMSIA model with q2 of 0.662 and r2 of 0.970 was obtained from the combination of steric, electrostatic and hydrogen bond acceptor fields. The predictive power of the models were assessed using an external test set of 14 compounds and showed reasonable external predictabilities (r2pred) of 0.668 and 0.641 for CoMFA and CoMSIA models, respectively. The models were further evaluated by leave-ten-out cross-validation, bootstrapping and progressive scrambling analyses. The study provides valuable information about the key structural elements that are required in the rational design of potential drug candidates of this class of Chk1 inhibitors.
Additional file 5 of Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling
Creators: name: Caputo, Luca
name: Granados, Alice
name: Lenzi, Jessica
name: Rosa, Alessandro
name: Ait-Si-Ali, Slimane
name: Puri, Pier Lorenzo
name: Albini, Sonia
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Marine Biology

description: Additional file 5: Figure S5. Pro-fibrotic gene activation in differentiated human myoblasts following electrical pacing.
Asymmetric Total Synthesis of Stagonolide F
Creators: name: B. Chinnababu
name: S. Purushotham Reddy
name: K. Suresh Babu
name: Y. Venkateswarlu
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Biochemistry
subject: Biophysics

description: A highly convergent stereoselective total synthesis of stagonolide F is described starting from commercially available 5-hexen 1-ol using asymmetric dihydroxylation, Jacobsen's hydrolytic kinetic resolution (HKR), regioselective epoxide ring opening with vinyl Grignard reaction, followed by esterfication and ring-closing metathesis (RCM) as key steps.
Fabrication of homogeneous and heterogeneous surface enhanced Raman spectroscopy substrates for the detection of genetic biomarkers of diseases
Creators: name: Chheda, Jinisha
Publisher: name: No Publisher Supplied
Year: 2024

description: The demand for cost-effective, rapid, and precise diagnostic tools for genetic diseases, such as cancer, remains unmet. Detecting mutations in disease-specific micro-RNA biomarkers presents a promising avenue for early disease screening. Liquid biopsy-based noninvasive diagnostic methods are gaining traction. Surface-enhanced Raman spectroscopy (SERS), renowned for its sensitivity, specificity, and multiplexed analysis capabilities, stands out for identifying single-base variations in nucleic acid sequences. Our hypothesis centers on leveraging SERS to detect nucleotide changes, like substitution or transposition, within these sequences. To this end, a homogeneous SERS substrate comprising colloidal silver nanospheres was meticulously developed and optimized via wet chemical synthesis. This substrate showcases homogeneity in particle size, optimal nanoparticle-analyte interaction, and substantial SERS signal enhancement. Our analysis of short single-stranded DNA and RNA sequences using this platform revealed its sensitivity in detecting single-base changes, reflecting as shifts in spectral peak intensity or position. To enhance the platform's efficiency in discerning oligonucleotide changes, we employed a Gaussian process-based hypothesis testing algorithm. This approach achieved a remarkable 95% accuracy in distinguishing between two nucleic acid analytes. Integrating SERS with machine learning proved highly sensitive in detecting sequential changes in the well-established prostate cancer biomarker, micro-RNA miR-21, thus validating the SERS platform's diagnostic potential. Moreover, beyond colloidal silver nanoparticles, we engineered a heterogeneous SERS substrate comprising a uniformly arranged array of gold nanostars. The three step-based bottom-up fabrication method used to develop the heterogenous substrate was highly cost-effective and resulted in nanoparticle arrangement precision similar to top-down lithographic techniques, which enables exceptional SERS enhancement for the analysis of oligonucleotides, offering reusability and maintaining stability over extended periods. Our work meticulously details the successful fabrication of SERS substrates and their application in detecting alterations in nucleic acid sequences. This research underscores the promising prospects of SERS-based platforms for diagnostic applications.