cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Examining sialic acid derivatives as potential inhibitors of SARS-CoV-2 spike protein receptor binding domain
Creators: name: Banerjee, Tanumoy
name: Gosai, Agnivo
name: Yousefi, Niloofar
name: Garibay, Ozlem Ozmen
name: Seal, Sudipta
name: Balasubramanian, Ganesh
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has been the primary reason behind the COVID-19 global pandemic which has affected millions of lives worldwide. The fundamental cause of the infection is the molecular binding of the viral spike protein receptor binding domain (SP-RBD) with the human cell angiotensin-converting enzyme 2 (ACE2) receptor. The infection can be prevented if the binding of RBD-ACE2 is resisted by utilizing certain inhibitors or drugs that demonstrate strong binding affinity towards the SP RBD. Sialic acid based glycans found widely in human cells and tissues have notable propensity of binding to viral proteins of the coronaviridae family. Recent experimental literature have used N-acetyl neuraminic acid (Sialic acid) to create diagnostic sensors for SARS-CoV-2, but a detailed interrogation of the underlying molecular mechanisms is warranted. Here, we perform all atom molecular dynamics (MD) simulations for the complexes of certain Sialic acid-based molecules with that of SP RBD of SARS CoV-2. Our results indicate that Sialic acid not only reproduces a binding affinity comparable to the RBD-ACE2 interactions, it also assumes the longest time to dissociate completely from the protein binding pocket of SP RBD. Our predictions corroborate that a combination of electrostatic and van der Waals energies as well the polar hydrogen bond interactions between the RBD residues and the inhibitors influence free energy of binding. Communicated by Ramaswamy H. Sarma
Titelei
Creators: name: Redaktion, Die
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
title: Feeding And Condition Of Juvenile Cod (Gadus Morhua). Combining Experimental And Field Data
Creators: name: Paulsen, Helge
Publisher: name: ASC 2001 - V - Theme session
Year: 2024
Subjects: Fisheries and aquaculture
ICES resources

description: No abstracts are to be cited without prior reference to the author.Feeding rhythm and nutritional status of juvenile cod has been investigated using mesocosm, laboratory and field samples of fish of comparable size (6-10cm) and temperature conditions (13-14°C). Results from the mesocosm showed an exponential stomach evacuation and a feeding rhythm with two non-feeding periods (noon to late afternoon and midnight to morning). Field samples taken over a 24hour period in Skagerrak (1995 and 1996) showed higher variation in stomach content weight than the mesocosm samples, and only one period of no-feeding could be observed. Daily ration was comparable in the mesocosm (70, 101 and 81mg dw*g dw-1*d-1) and the 1995 field samples (98mg), but only 49mg in the 1996 field samples. Stomach content weight, liver index and condition factor (Fulton K) were determined in juveniles sampled by trawling on a total of 26 locations in the Skagerrak, Kattegat and western Baltic in early August 1996, 1997 and 1998. The results showed no indications of inferior growth or nutritional status in specific areas, but local indications of food limitations were observed. Total catch and liver index of 1996 juveniles were significantly lower than for 1997 and 1998. Total catch of the 1996 cohort, as one year old in 1997, was also lower than of one year old in 1998. These results appear to be in conflict with the 1996 year-class of North Sea cod being very large.
Sonnenfleckenzeichnung Nr. 75.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.04.1972, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
Bericht des Dendrochronologischen Forschungslabors am Rheinischen Landesmuseum Trier 2008-2015
Creators: name: Neyses-Eiden, Mechthild
name: Rzepecki, Andreas
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Sonnenfleckenzeichnung Nr. 67.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.04.1972, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
title: The Relationship Between Growth And Age At Maturity In North Sea Cod
Creators: name: Rochet, Marie-Joëlle
Publisher: name: ASC 2001 - V - Theme session
Year: 2024
Subjects: Fisheries and aquaculture
ICES resources

description: No abstracts are to be cited without prior reference to the author.Both growth and age at maturity vary in time under the influence of various factors, including fishing. Moreover, their variations are likely to be linked because both depend on available food and on regulation processes at the population level. Examining the link between growth and maturation might improve our understanding of stock production and dynamics. Here a simple model is used that differentiates prematurity growth, in which all surplus energy is devoted to growth, from postmaturity growth, in which a part of surplus energy is devoted to reproduction. This model is fitted to length-at-age and maturity data obtained from the International Bottom Trawl Survey (IBTS) in the North Sea for the period 1983-2000. The variability of the estimated parameters is examined to distinguish those which might depend on population abundance.
title: Ανάλυση και αξιολόγηση καινοτόμων συστημάτων μετατροπής CO2 σε εναλλακτικές μορφές ενέργειας
title: Analysis and evaluation of novel systems that convert CO2 to alternative energy sources
Creators: name: Περουλακη Λυδια
Publisher: name: Technical University of Crete
Year: 2022

description: Τα συστήματα δέσμευσης, αποθήκευσης του CO2 και μετατροπής αυτού σε εναλλακτικές μορφές ενέργειας είναι από τις σημαντικότερες τεχνολογίες που θα μπορούσαν να επιφέρουν άμεσες λύσεις για τον περιορισμό των εκπομπών του CO2 σε συνδυασμό πάντα και με τις γνωστές ανανεώσιμες πηγές ενέργειας (ΑΠΕ).
Στην παρούσα διπλωματική εργασία, αναλύονται ορισμένες τεχνολογίες αξιοποίησης του CO2 προς εναλλακτικές μορφές ενέργειας. Ειδικότερα, μελετάται η υδρογόνωση του CO2 προς το σχηματισμό μεθανίου, μεθανόλης και αερίου σύνθεσης. Σκοπός της εργασίας αποτελεί η ανάλυση λειτουργίας (μέσα από βιβλιογραφικές πηγές), καθώς και η οικονομοτεχνική αξιολόγηση της εφαρμογής τέτοιων καινοτόμων συστημάτων αξιοποίησης  του CO2 που παράγεται από βιομηχανικές εγκαταστάσεις όπως οι τσιμεντοβιομηχανίες και τα εργοστάσια παραγωγής ενέργειας από λιγνίτη. Από τις μελέτες που εξετάστηκαν, το χαμηλότερο κόστος υπηρεσιών κοινής ωφελείας παρουσίασε η μετατροπή του CO2 σε μεθανόλη, ενώ παράλληλα εμφάνισε το μέγιστο λειτουργικό κόστος και κόστος κεφαλαίου. Όσων αφορά το κόστος παραγωγής κάθε μονάδας, η πιο οικονομικά συμφέρουσα μέθοδος παρουσιάζεται για την παραγωγή του syngas μέσω βιοαντιδραστήρα.  Το μεγαλύτερο κέρδος παρουσιάστηκε σε έρευνα που εκπονήθηκε στο Πολυτεχνείο Κρήτης, με την τιμή του προϊόντος (μεθανίου) να ανέρχεται σε περίπου 280 εκατομμύρια €/έτος, ενώ το ελάχιστο κέρδος εμφάνισε η έρευνα για τη παραγωγή του syngas (βέβαια να τονισθεί πως αναφερόμαστε σε απόλυτα νούμερα και τιμές). Στα πλαίσια αυτά, το προϊόν που εμφάνισε το ελάχιστο κόστος ήταν η μεθανόλη με την τιμή της να ανέρχεται σε 1,08€/kg, ενώ ακολουθεί το αέριο σύνθεσης με 1,34€/kg. Αντίθετα η τιμή πώλησης του μεθανίου φαίνεται ότι είναι κατά πολύ ακριβότερη και υπερβαίνει και τις διαθέσιμες τιμές που υπάρχουν στην αγορά.
Σημειώνεται ότι οι τιμές των παραγώγων που εξετάστηκαν έχουν αποκλίσεις από τις τιμές εμπορίου ενώ έχουν και αυξημένο κόστος παραγωγής. Ως επακόλουθο, θα πρέπει να γίνουν κάποιες ενέργειες προκειμένου οι μελλοντικές έρευνες να οδηγήσουν στην λειτουργική και οικονομική βελτιστοποίηση των εργοστασίων που θα έχουν τη δυνατότητα να μετατρέψουν το CO2 σε χημικά παράγωγα όπως το μεθάνιο, η μεθανόλη και το syngas, ώστε αυτά τα εργοστάσια να είναι βιώσιμα.
title: Sectional anatomy of the knee at MR arthrography with 70° knee flexion simulating operative arthroscopic condition
Creators: name: Lee, Young Han
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Musculoskeletal joint
subject: Musculoskeletal system
subject: Musculoskeletal - Joints

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: The purpose of this article is to describe the normal sectional anatomy of the knee MR arthrography by 70° flexion of the knee, simulating the operative arthroscopic...
Jahresbericht der Archäologischen Denkmalpflege für den Stadtbereich Trier 2014-2015
Creators: name: Hupe, Joachim
name: Dodt, Michael
name: Goethert, Klaus-Peter
name: Teegen, Wolf-Rüdiger
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
title: СМЕРТНОСТЬ НАСЕЛЕНИЯ В ТАБЛИЦАХ ДОЖИТИЯ
Creators: name: Шаповалова, Марина Александровна
name: Бойко, Юрий Павлович
name: Ярославцев, Александр Станиславович
name: Бабеева, Наталья Ивановна
name: Перепечкин, Александр Николаевич
name: Зурнаджъянц, Юлия Александровна
name: Орлов, Федор Викторович
name: Угурчиева, Хяди Юсуповна
name: Суслова, Татьяна Анатольевна
name: Абрамова, Дарья Алексеевна
Publisher: name: Астраханский государственный медицинский университет
Year: 2022
Subjects: subject: Clinical medicine
subject: FOS: Clinical medicine

description: Аннотация. Анализ демографических процессов является необходимой основой планиро-вания и реализации государственных социальных программ, оценки их эффективности. Сохра-нение и увеличение численности населения является важнейшей государственной задачей, и важнейшие демографические показатели ее оценки находят отражение в Национальных проек-тах. Изменения демографических показателей носят инертный характер, не сразу реагируют на проводимые государством меры и нуждаются в мониторировании и оценке. Наиболее объек-тивными, изолированными от внешних, в том числе случайных факторов являются величины показателей модельных демографических таблиц. Использование статистических методов оценки динамики расчетных демографических величин демографических таблиц позволяет оце-нивать демографические тенденции, планировать и проектировать программы развития терри-тории.
Ο ρόλος του Κριτικού Γραμματισμού στην διαμόρφωση των επαγγελματικών ταυτοτήτων των εκπαιδευτικών. Μια συγκριτική Προσέγγιση
Creators: name: Ποτόλια, Χρυσή Κοσμά
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Κριτικός Γραμματισμός
Επαγγελματική Ταυτότητα
Επικοινωνιακή προσέγγιση
Critical Literacy
Professional Identity
Communicative Approach

description: Στη παρούσα διπλωματική εργασία επιχειρείται η σύγκριση μεταξύ δύο ομάδων εκπαιδευτικών με στόχο τη διερεύνηση των επαγγελματικών ταυτοτήτων τους και την πιθανή επίδραση που μπορεί να έχουν οι σπουδές στην προσέγγιση του Κριτικού Γραμματισμού. Διενεργήθηκε ποιοτική έρευνα με συνεντεύξεις σε δύο ομάδες εκπαιδευτικών όπου η πρώτη αφορούσε εκπαιδευτικούς που είχαν υπόβαθρο Κριτικού Γραμματισμού και η δεύτερη ομάδα απαρτιζόταν από εκπαιδευτικούς χωρίς το σχετικό υπόβαθρο. Η ανάλυση των δεδομένων έγινε με βάση της μεθόδου της Κατασκευής Θεματικού Ευρετηρίου (Index Analysis) και δημιουργήθηκαν συγκριτικοί πίνακες με βάση τον αντίστοιχο άξονα συζήτησης. Τα αποτελέσματα της έρευνας έδειξαν τόσο ομοιότητες όσο και διαφορές μεταξύ των επαγγελματικών ταυτοτήτων των εκπαιδευτικών τόσο σε διομαδικό όσο και σε ενδοομαδικό επίπεδο. Πιο συγκεκριμένα, φάνηκαν περισσότερα στοιχεία επίδρασης της επικοινωνιακής προσέγγισης στην ομάδα των εκπαιδευτικών με υπόβαθρο Κριτικού Γραμματισμού και μόνο μερικά στοιχεία της προσέγγισης του Κριτικού Γραμματισμού, ενώ η ομάδα χωρίς το εν λόγω υπόβαθρο ακολουθούσε περισσότερο την δομιστική προσέγγιση, όπως εκφράστηκε στους στόχους του γλωσσικού μαθήματος και στην επεξεργασία του κειμένου.
description: In this thesis, the comparison between two groups of teachers is attempted with the aim of investigating their professional identities and the possible effect of the Critical Literacy approach. Qualitative research was conducted with interviews in two groups of teachers where the first group involved teachers who had a Critical Literacy background and the second group consisted of teachers without the relevant background. The analysis of the data was done based on the method of Index Analysis and comparative tables were created based on the respective axis of discussion. The results of the research showed both similarities and differences between the professional identities of the teachers both at the inter-group and intra-group level. More specifically, more evidence of the effect of the communicative approach was seen in the group of teachers with a Critical Literacy background and only some evidence of the Critical Literacy approach, while the group without this background followed more of the structural approach as expressed in the objectives of the language lesson and in the editing of the text.
Sonnenfleckenzeichnung Nr. 257.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.11.1972, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
On Q-balls in Anti de Sitter Space
Creators: name: Rajaraman, Arvind
name: Stewart, Alexander
name: Verhaaren, Christopher B.
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We perform a general analysis of thin-wall Q-balls in AdS space. We provide numeric solutions and highly accurate analytic approximations over much of the parameter space. These analytic solutions show that AdS Q-balls exhibit significant differences from the corresponding flat space solitons. This includes having a maximum radius beyond which the Q-balls are unstable to a new type of state where the Q-ball coexists with a gas of massive particles. The phase transition to this novel state is found to be a zero-temperature third-order transition. This, through the AdS/CFT correspondence, has implications for a scalar condensate in the boundary theory.
description: 21 pages, 10 figures. Updated to published version
A review on computational studies and bioinformatics analysis of potential drugs against monkeypox virus
Creators: name: Hossain, Ferdaus Mohd Altaf
name: Bappy, Md. Nazmul Islam
name: Robin, Tanjin Barketullah
name: Ahmad, Iqrar
name: Patel, Harun
name: Jahan, Nusrat
name: Rabbi, Md Gulam Rabbany
name: Roy, Anindita
name: Chowdhury, Wasima
name: Ahmed, Nadim
name: Prome, Anindita Ash
name: Rani, Nurul Amin
name: Khan, Parvez
name: Zinnah, Kazi Md. Ali
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Monkeypox, a viral disease that is caused by monkeypox virus and occurs mainly in central and western Africa. However, recently it is spreading worldwide and took the focus of the scientific world towards it. Therefore, we made an attempt to cluster all the related information that may make it easy for the researchers to get the information easily and carry out their research smoothly to find prophylaxis against this emerging virus. There are very few researches found available on monkeypox. Almost all the studies were focused on smallpox virus and the recommended vaccines and therapeutics for monkeypox virus were originally developed for smallpox virus. Though these are recommended for emergency cases, they are not fully effective and specific against monkeypox. For this, here we also took the help of bioinformatics tools to screen potential drug candidates against this growing burden. Some potential antiviral plant metabolites, inhibitors and available drugs were scrutinized that can block the essential survival proteins of this virus. All the compounds Amentoflavone, Pseudohypericin, Adefovirdipiboxil, Fialuridin, Novobiocin and Ofloxacin showed elite binding efficiency with suitable ADME properties and Amentoflavone and Pseudohypericin showed stability in MD simulation study indicating their potency as probable drugs against this emerging virus. Communicated by Ramaswamy H. Sarma
title: How to improve shoulder arthrography using an anterior approach
Creators: name: Redondo Carazo, Maria Victoria
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Musculoskeletal joint
subject: Musculoskeletal system
subject: Musculoskeletal - Joints

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Theobjective of our study was to improve and optimize anterior MR arthrography of the shoulder by comparing three injection sites: the upper third of the medial part of the humeral head, the lower third of the medial part of the humeral head,and the...
title: Effect Of Experience On Feeding Behaviour: Captive-Bred Cod Adapt More Slowly To Prey Encountered In A Novel Manner Than Do Wild Cod
Creators: name: Salvanes, A. G. V.
Publisher: name: ASC 2001 - V - Theme session
Year: 2024
Subjects: Fisheries and aquaculture
ICES resources

description: No abstracts are to be cited without prior reference to the author.When captive-bred cod were released for sea ranching in Masfjorden of western Norway, it was evident from field samples that these fish had a different diet and higher mortality rate than wild cod at least the first tree days after release. Moreover, these captive-bred cod were released into the natural habitat in a number that largely exceeded that of wild cod. Despite of this their abundance reduced dramatically during the spring as one year old and just six months after the releases. In this paper I study experimentally if groups of captive-bred cod have a different feeding behaviour than wild cod and if they adapt differently to prey. Results show that captive-bred cod adapted more slowly than wild to prey that were encountered sequentially, which represents a novel feeding context compared to hatcheries where fish usually obtain many prey simultaneously although both wild and captive-bred had taken these prey earlier when many were given. Wild cod had higher feeding rates that increased rapidly with treatment day. Captive-bred cod refused to take prey the first five treatment days, spent more time on each prey item and obtained the lowest growth rates. A positive effect of group size on feeding skills was found for captive-bred cod but not for wild, but even so, their growth rate was lower than that of wild. I discuss these results in the light of the different experience the fish had gained prior to the experiments and possible consequences for sea ranching.
Die befestigte Villa von Bodenbach (Landkreis Vulkaneifel) im Kontext der spätantiken Befestigungen Nordgalliens und Niedergermaniens
Creators: name: Henrich, Peter
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Sonnenfleckenzeichnung Nr. 38.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.03.1972, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
Polyharmonic hypersurfaces into complex space forms
Creators: name: Balado-Alves, José Miguel
Publisher: name: arXiv
Year: 2023
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 58E20, 53C43

description: We characterize homogeneous hypersurfaces in complex space forms which arise as critical points of a higher order energy functional. As a consequence, we obtain existence and non-existence results for $\mathbb{CP}^n$ and $\mathbb{CH}^n$, respectively. Moreover, we study the stability of biharmonic hypersurfaces and compute the normal index for a large family of solutions.
description: 16 pages, 0 figures. v2: new references, Corollary 5.3 has been improved, and some minor changes. v3: improved exposition
Ikonographische Überlegungen zum Trierer Liviaporträt
Creators: name: Boschung, Dietrich
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
title: Magnetic resonance imaging of articular cartilage of the knee using ultrashort TE sequences with radial acquisition
Creators: name: Fujii, Masahiko
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Musculoskeletal joint
subject: Musculoskeletal system
subject: Musculoskeletal - Joints

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: The articular cartilage consists of four layers (Fig 1.), superficial, middle, deep and calcified, which results in changes in T2 values(Fig 2.). It is well known that the degeneration of the cartilage originates in the superficial layer. According...
title: Педагогика высшей школы: коммуникативно-деятельностный подход
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2022

description: В учебном пособии рассматриваются актуальные проблемы педагогики высшей школы, предлагается новый подход к формированию педагогической компетентности, основанный на понимании базовых категорий педагогики в свете тенденций современного образовательного пространства, а также на становлении умений и навыков педагогического общения в офлайн- и онлайн-форматах. Издание создано авторами, преподавателями российских вузов с большим педагогическим стажем работы, и во многом отражает их личный опыт преподавательской деятельности. Подготовлено в соответствии с требованиями Федерального государственного образовательного стандарта высшего образования, предъявляемыми к изучению дисциплины «Педагогика высшей школы». Предназначено для студентов магистратуры, обучающихся по направлению подготовки 44.04.01 «Педагогическое образование», а также для аспирантов (в том числе из ближнего и дальнего зарубежья) различных непрофильных вузов. Издание может быть успешно использовано начинающими преподавателями, не имеющими диплома педагога, и слушателями курсов повышения квалификации, включающих курс «Педагогика».
Ein Paar silberne Scheibenfibeln der frühen Kaiserzeit aus Trier
Creators: name: Martin-Kilcher, Stefanie
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Die römische Stadtmauer im Trierer Amphitheater : Ein Forschungsproblem im Licht alter und neuer Untersuchungen
Creators: name: Hupe, Joachim
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Immunoinformatic-guided novel mRNA vaccine designing to elicit immunogenic responses against the endemic Monkeypox virus
Creators: name: Aiman, Sara
name: Ali, Yasir
name: Malik, Abdul
name: Alkholief, Musaed
name: Ahmad, Abbas
name: Akhtar, Suhail
name: Ali, Sajid
name: Khan, Asifullah
name: Li, Chunhua
name: Shams, Sulaiman
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Monkeypox virus (MPXV) is an orthopoxvirus, causing zoonotic infections in humans with smallpox-like symptoms. The WHO reported MPXV cases in May 2022 and the outbreak caused significant morbidity threats to immunocompromised individuals and children. Currently, no clinically validated therapies are available against MPXV infections. The present study is based on immunoinformatics approaches to design mRNA-based novel vaccine models against MPXV. Three proteins were prioritized based on high antigenicity, low allergenicity, and toxicity values to predict T- and B-cell epitopes. Lead T- and B-cell epitopes were used to design vaccine constructs, linked with epitope-specific linkers and adjuvant to enhance immune responses. Additional sequences, including Kozak sequence, MITD sequence, tPA sequence, Goblin 5’, 3’ UTRs, and a poly(A) tail were added to design stable and highly immunogenic mRNA vaccine construct. High-quality structures were predicted by molecular modeling and 3D-structural validation of the vaccine construct. Population coverage and epitope-conservancy speculated broader protection of designed vaccine model against multiple MPXV infectious strains. MPXV-V4 was eventually prioritized based on its physicochemical and immunological parameters and docking scores. Molecular dynamics and immune simulations analyses predicted significant structural stability and binding affinity of the top-ranked vaccine model with immune receptors to elicit cellular and humoral immunogenic responses against the MPXV. The pursuance of experimental and clinical follow-up of these prioritized constructs may lay the groundwork to develop safe and effective vaccine against MPXV. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 234.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.10.1972, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
title: Osteochondroses and aseptic osteonecroses of the lower limb: MRI from hip to toe
Creators: name: Schubert, Roberto
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Musculoskeletal joint
subject: Musculoskeletal system
subject: Musculoskeletal - Joints

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: To review the MRI features of osteochondroses and aseptic bone necroses in the lower extremities. To discuss the advantages and the drawbacks of MR imaging in osteochondronecroses (OCNs). To recognise main differences between OCNs in childhood and...
title: Disentangling Effects Of Size-Selective Mortality, Density, And Temperature On Length-At-Age Of Atlantic Cod (Gadus Morhua) In The Southern Gulf Of St. Lawrence
Creators: name: Sinclair, Alan F.
name: Swain, Douglas P.
name: Hanson, J. Mark
Publisher: name: ASC 2001 - V - Theme session
Year: 2024
Subjects: Fisheries and aquaculture
ICES resources

description: No abstracts are to be cited without prior reference to the author.Dramatic changes have occurred in length-at-age of Atlantic cod in the southern Gulf of St. Lawrence over the past 30 yr. We assessed the relative contributions of variation in size-selective mortality, density, and temperature to these changes. We examined size-selective mortality using a 28-yr time series of backcalculated length-at-age. Striking changes in size selection occurred over the time series, from directional selection favouring large size in the early cohorts, through disruptive selection in intermediate cohorts, to directional selection favouring small size in late cohorts. We simultaneously tested effects of these changes in size selection and effects of density and temperature using a modified von Bertalanffy growth model in which each annual growth increment depended on indices of temperature, population density and size selection. The model was fit to observed population mean lengths-at-age for ages 5-11 yr. The backcalculated length at age 4 yr was included as a covariate in the model to account for variation in growth at earlier ages. The strongest effect on mean length-at-age was variation in size-selective mortality, followed by a negative effect of population density, and a weak positive effect of cod ambient temperature.
title: High resolution in vivo MR imaging of inner ear microstructures in utero in fetal sheep
Creators: name: Buhk, Jan-Hendrik
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Paediatric
subject: Pediatric - Miscellaneous

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Clinical Background Fetal MRI today: Reasonable addition to ultrasound in uncertain cases, not only regarding central nervous system (1-7). Developmental inner ear abnormalities can occur due to several reasons: Embryopathies, e.g. Rubella and...
title: Optimization of anode-filter combinations in digital mammography: An experimental study
Creators: name: Peruzzo Cornetto, Andrea
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Physics
subject: Physics in Radiology - Without Subtopic

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Most of digital mammography systems are now developed with a tungsten anode because of the good matching of its physical characteristics (high atomic number, high x-ray output fluence) with the digital detectors features. Tungsten spectrum shows...
Protein sequence comparison based on representation on a finite dimensional unit hypercube
Creators: name: Ghosh, Soumen
name: Pal, Jayanta
name: Cattani, Carlo
name: Maji, Bansibadan
name: Bhattacharya, Dilip Kumar
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Numerous techniques are used to compare protein sequences based on the values of the physiochemical properties of amino acids. In this work, a single physical/chemical property value based non-binary representation of protein sequences is obtained on a 20 × 20-dimensional unit hypercube. The represented vector expressed in the matrix form is taken as the descriptor. The generalized NTV metric, which is an extension of the NTV metric used for polynucleotide space is taken as a distance measure. Based on this distance measure, a distance matrix is obtained for protein sequence comparison. Using this distance matrix, phylogenetic trees are drawn by using Molecular Evolutionary Genetics Analysis 11 (MEGA11) software applying the neighbor-joining method. Data sets used in this current work are 9-ND4, 9-ND5, 9-ND6, 24 TF-LF proteins, 27 different viruses and 127 proteins from the protein kinase C (PKC) family. Two sets of phylogenetic trees are obtained – one based on property value of polarity and the other based on property value of molecular weight. They are found to be exactly the same. Similar results also hold for other single property value based representation. The present trees are individually tested for efficiency based on the criterion of rationalized perception and computational time. The results of the present method are compared with those obtained earlier by other methods on the same protein sequences using assessment criteria of Symmetric distance (SD), Correlation coefficient, and Rationalized perception. In all the cases, the present results are found to be better than the results of other methods under comparison. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 197.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.09.1972, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
title: Photoacoustic tomography of pathological tissue in ex-vivo mouse hearts
Creators: name: Esterhammer, Regina
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Physics
subject: Physics in Radiology - Without Subtopic

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Photoacoustic imaging (PAI) is becoming a major tool for preclinical studies owing to its unique property of combining aspects of optical and ultrasound imaging. In the present study, we evaluate the applicability of ex-vivo photoacoustic imaging...
Sonnenfleckenzeichnung Nr. 205.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.09.1972, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
title: Evaluation of a new instrument for on-site dose area product meter calibration
Creators: name: Bacher, Klaus
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Physics
subject: Physics in Radiology - Without Subtopic

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Dose area product (DAP) measurements play a central role in the patient dose assessmentin X-ray diagnostics.Especially in applications using fluoroscopy (interventional radiology and cardiology), DAP measurements are important. Therefore, DAP meters...
Sonnenfleckenzeichnung Nr. 235.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.10.1972, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
Structure-activity relationship mediated molecular insights of DprE1 inhibitors: A Comprehensive Review
Creators: name: Dash, Swagatika
name: Rathi, Ekta
name: Kumar, Avinash
name: Chawla, Kiran
name: Joseph, Alex
name: Kini, Suvarna G.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Emerging threats of multi-drug resistant (MDR), extensively drug-resistant (XDR), and totally drug-resistant (TDR) tuberculosis led to the discovery of a novel target which was entitled Decaprenylphosphoryl-β-D-ribose 2’-epimerase (DprE1) enzyme. DprE1 is composed of two isoforms, decaprenylphosphoryl-β-D-ribose oxidase (DprE1) and decaprenylphosphoryl-D-2-keto erythro pentose reductase (DprE2). The enzymes, DprE1 and DprE2, regulate the two-step epimerization process to form DPA (Decaprenylphosphoryl arabinose) from DPX (Decaprenylphosphoryl-D-ribose), which is the sole precursor in the cell wall synthesis of arabinogalactan (AG) and lipoarabinomannan (LAM). Target-based and whole-cell-based screening played an imperative role in the identification of the druggable target, DprE1, whereas the druggability of the DprE2 enzyme is not proved yet. To date, diverse scaffolds of heterocyclic and aromatic ring systems have been reported as DprE1 inhibitors based on their interaction mode, i.e. covalent, and non-covalent inhibitors. This review describes the structure-activity relationship (SAR) of reported covalent and non-covalent inhibitors to enlighten about the crucial pharmacophoric features required for DprE1 inhibition, along with in-silico studies which characterize the amino acid residues responsible for covalent and non-covalent interactions. Communicated by Ramaswamy H. Sarma
Bibliographie Lothar Schwinden
Creators: name: Merten, Jürgen
name: Schulz, Kristina
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Bibliographie Hans Nortmann
Creators: name: Merten, Jürgen
name: Schulz, Kristina
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2022

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 79/80 (2016/2017): Trierer Zeitschrift : Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Sonnenfleckenzeichnung Nr. 12.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.01.1976, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1976

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
title: A centralised software solution for quality control in a radiology department
Creators: name: Bokou, Christina
Publisher: name: European Congress of Radiology
Year: 2010
Subjects: subject: Physics
subject: Physics in Radiology - Without Subtopic

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Quality assurance and regular quality control in a radiology department is mandatory and regulated by law (1). Regular technical evaluation of imaging modalities (RX, CT, MRI) is perfomed using test objects and a radiology technologist has to...
Sonnenfleckenzeichnung Nr. 274.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.12.1972, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
title: Interannual Variation In Gonadal Maturation Of Cod In The Gotland Basin Of The Baltic Sea: Influence Of Environment And Fish Condition
Creators: name: Uzars, D.
name: Baranova, T.
name: Yula, E.
Publisher: name: ASC 2001 - V - Theme session
Year: 2024
Subjects: Fisheries and aquaculture
ICES resources

description: No abstracts are to be cited without prior reference to the author.Analysis of the long-term biological data sets (1967-1990) on diet, liver weight and maturation of cod revealed the general trends in accumulation of energy in the liver and gonadal maturation dynamics. The study confirms relationship between energetic condition of cod and food supply. The liver condition index of cod and abundance of clupeids in cod food during the autumn/winter and spring was positively correlated. The sex- and maturation-specific differences in cod diet, liver weight, and utilization of energy for gonadal growth and spawning were defined. The ripening females on the spawning grounds were hardly feeding on clupeids. Liver condition index of females continued to increased and reached the maximum at the final maturation stage. The feeding intensity and liver condition index of maturing males decreased earlier than of females at the final gonad ripening stage. Cod of both sexes at spawning condition nearly ceased feeding. The liver condition index declined. In 1967-1977, at favourable oxygen/temperature conditions on the spawning grounds, the gonad development trends prior to the spawning in January determined the gonad growth during the main spawning season in March-April. During the 1980s the spawning population of cod was influenced by poor hydrographic conditions - low oxygen saturation and temperature. The changes in distribution and age composition of the spawning population of cod caused a decline in proportion of males on the spawning grounds. The diverging courses of proportion of maturing cod in prespawning and spawning seasons indicated that hydrographic conditions likely were the cause of the gonad development delay and spawning disturbance during the stagnation period of 1980s.
Sonnenfleckenzeichnung Nr. 104.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.05.1972, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1972

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert