cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Facilitating the sharing of electrophysiology data analysis results through in-depth provenance capture
Creators: name: Köhler, Cristiano André
name: Ulianych, Danylo
name: Grün, Sonja
name: Decker, Stefan
name: Denker, Michael
Publisher: name: Forschungzentrum Jülich
Year: 2023
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: arXiv (2023). doi:10.48550/ARXIV.2311.09672
description: Scientific research demands reproducibility and transparency, particularly in data-intensive fields like electrophysiology. Electrophysiology data is typically analyzed using scripts that generate output files, including figures. Handling these results poses several challenges due to the complexity and interactivity of the analysis process. These stem from the difficulty to discern the analysis steps, parameters, and data flow from the results, making knowledge transfer and findability challenging in collaborative settings. Provenance information tracks data lineage and processes applied to it, and provenance capture during the execution of an analysis script can address those challenges. We present Alpaca (Automated Lightweight Provenance Capture), a tool that captures fine-grained provenance information with minimal user intervention when running data analysis pipelines implemented in Python scripts. Alpaca records inputs, outputs, and function parameters and structures information according to the W3C PROV standard. We demonstrate the tool using a realistic use case involving multichannel local field potential recordings of a neurophysiological experiment, highlighting how the tool makes result details known in a standardized manner in order to address the challenges of the analysis process. Ultimately, using Alpaca will help to represent results according to the FAIR principles, which will improve research reproducibility and facilitate sharing the results of data analyses.
description: Published by arXiv
Testing Dispersion Relations of Quantum $κ$-Poincaré Algebra on Cosmological Ground
Creators: name: Kowalski-Glikman, J.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Following the procedure proposed recently by Martin and Brandenberger we investigate the spectrum of the cosmological perturbations in the case when the ``trans-Plackian'' dispersion relations are motivated by the quantum $κ$-Poincaré algebra. We find that depending on the choice of initial conditions of the perturbations, the spectrum either differs from the flat one for for instantaneous Minkowski vacuum or, in the case of initial conditions minimizing energy density, leads to the observed scale-invariant Harrison-Zel'dovich spectrum in the Friedmann epoch.
description: revised version to be published in Phys. Lett. B
Papilio panthous Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Papilionidae
Papilio
Papilio panthous

description: Papilio panthous [spec. nov.]
P. E. alis dentatis nigris concoloribus: primoribus albo maculatis; posticis maculis albis nigra foetis. M. L. U.
Habitat in Indiis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 461, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
D5.4 Open API and interoperability
Creators: name: GLOMICAVE partners
Publisher: name: Zenodo
Year: 2023

description: This document outlines the task focused on establishing interoperable mechanisms to streamline access to digital services and orchestrate the entire GLOMICAVE platform. The primary objective is the orchestration of GLOMICAVE modules, encompassing the data lake, analytical services, and visualization components.This report particularly emphasizes two pivotal aspects: the development of a Backend API for executing data processing services and a Backend API for data interaction using the Gremlin API with the Neptune Graph Database. These components will strengthen GLOMICAVE's ability to efficiently process data and foster comprehensive data interaction.

This strategic approach not only enhances GLOMICAVE's technical functionality but also contributes to its international standing. Key achievements are highlighted, challenges addressed, and guidelines for future implementations are provided, solidifying GLOMICAVE's role in genomics and research.The following sections have been included:

Section 1: information about the approach for the orchestration of modules (architecture and interaction)

Section 2: description of Open API for Analytical Services

Section 3: description of Open API for Data Querying

Section 4: practical applications of Open API

Section 5: conclusions and next steps
Laser Based Mid-Infrared Spectroscopic Imaging – Exploring a Novel Method for Application in Cancer Diagnosis
Creators: name: McCrow, Andrew
Publisher: name: Imperial College London
Year: 2011

description: A number of biomedical studies have shown that mid-infrared spectroscopic images can provide both morphological and biochemical information that can be used for the diagnosis of cancer. Whilst this technique has shown great potential it has yet to be employed by the medical profession. By replacing the conventional broadband thermal source employed in modern FTIR spectrometers with high-brightness, broadly tuneable laser based sources (QCLs and OPGs) we aim to solve one of the main obstacles to the transfer of this technology to the medical arena; namely poor signal to noise ratios at high spatial resolutions and short image acquisition times. In this thesis we take the first steps towards developing the optimum experimental configuration, the data processing algorithms and the spectroscopic image contrast and enhancement methods needed to utilise these high intensity laser based sources. We show that a QCL system is better suited to providing numerical absorbance values (biochemical information) than an OPG system primarily due to the QCL pulse stability. We also discuss practical protocols for the application of spectroscopic imaging to cancer diagnosis and present our spectroscopic imaging results from our laser based spectroscopic imaging experiments of oesophageal cancer tissue.
Additional file 3: of Co-delivery of sorafenib and metapristone encapsulated by CXCR4-targeted PLGA-PEG nanoparticles overcomes hepatocellular carcinoma resistance to sorafenib
Creators: name: Zheng, Ning
name: Liu, Weiqun
name: Li, Bifei
name: Nie, Huifang
name: Liu, Jian
name: Cheng, Yunlong
name: Wang, Jichuang
name: Dong, Haiyan
name: Jia, Lee
Publisher: name: figshare
Year: 2019
Subjects: Space Science
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology

description: Figure S3.1H NMR spectra of PLGA-PEG-COOH copolymer. (DOCX 93 kb)
Molecular simulation studies on the binding activity and selectivity of 3-amino-phenyl-5-chloro-pyrimidine-2, 4-diamine derivatives in complexes with kinases c-Met and ALK
Creators: name: You-Lu Pan
name: Liu, Yan-Ling
name: Chen, Jian-Zhong
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Receptor tyrosine kinases c-Met and ALK have been demonstrated to be important therapeutic targets for cancer therapy. However, selectivity and drug resistance could hinder the development of their corresponding inhibitors. In this study, three compounds with similar scaffold were examined to study activity and selectivity mechanism towards c-Met or ALK by utilising a combined approach of computational techniques, including flexible dock, molecular electrostatic potential (MESP) calculations, molecular dynamic (MD) simulation, and binding free-energy calculation. Molecular simulation provides us new chemical insights into steric and electronic complementarities of these inhibitors to target binding sites. The computed binding free energies were consistent with the changing trend of experimental affinities on c-Met and ALK. H-bond with Asp169 and hydrophobic interaction with Phe36 of c-Met, respectively, could be crucial for the binding affinity of an inhibitor binding to c-Met. Meanwhile, for inhibitor–ALK complex, both H-bond interactions with Arg28 and Met101 and hydrophobic interactions with Leu30, Val38, and Leu158 could enhance the bioactivity and selectivity. The present work may provide a structural understanding of molecular mechanism expected to be valuable for the guidelines of the development of new potent c-Met or ALK selective inhibitors.
Dense Information Flow for Neural Machine Translation
Creators: name: Shen, Yanyao
name: Tan, Xu
name: He, Di
name: Qin, Tao
name: Liu, Tie-Yan
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Recently, neural machine translation has achieved remarkable progress by introducing well-designed deep neural networks into its encoder-decoder framework. From the optimization perspective, residual connections are adopted to improve learning performance for both encoder and decoder in most of these deep architectures, and advanced attention connections are applied as well. Inspired by the success of the DenseNet model in computer vision problems, in this paper, we propose a densely connected NMT architecture (DenseNMT) that is able to train more efficiently for NMT. The proposed DenseNMT not only allows dense connection in creating new features for both encoder and decoder, but also uses the dense attention structure to improve attention quality. Our experiments on multiple datasets show that DenseNMT structure is more competitive and efficient.
Identifying a Targeting Factor for Rab27a
Creators: name: Booth, Antonia Elspeth Grace
Publisher: name: Imperial College London
Year: 2012

description: The Rab family of small GTPases regulate intracellular membrane trafficking pathways and each Rab GTPase localises to a discrete membrane compartment. The mechanism(s) by which this targeting is achieved remains to be elucidated. Previous work identified that the C‐terminal hypervariable domain and effector binding were not necessary for Rab27a targeting in melanocytes. However, GEF activity of the non‐redundant Rab27a GEF Rab3GEP (R3G) was required but not sufficient for Rab27a targeting. This led to the hypothesis of the involvement of a Rab27a targeting factor. A Rab27a mutant (Rab27aSF1/F4) had previously been characterised that maintained melanosomal targeting and GTP‐loading by R3G but bound to no known Rab27a effectors. Using this mutant, novel Rab27a interacting partners were identified and assessed for their possible role in Rab27a targeting. The current research identified ATP1a1 (the α1 subunit of Na+,K+‐ATPase) as a novel interacting partner for Rab27a in melanocytes, depletion of which resulted in perinuclear clustering of melanosomes, indicative of loss of Rab27a function. Depletion of ATP1a1 did not disrupt Rab27a membrane localisation but did reduce the levels of GTP‐bound Rab27a, comparable to what is seen following depletion of R3G. Crucially, depletion of ATP1a1 resulted in displacement of endogenous Rab27a from melanosomal membranes indicating a role in Rab27a targeting. Furthermore, ATP1a1 depletion disrupted the levels of other melanosomal proteins indicative of a disruption in melanogenesis. ATP1a1 is proposed to transiently associate with melanosomes and through its Na+,K+‐ATPase pump function regulate the lumenal pH, which indirectly regulates melanosome maturation. How the maturation of the lumenal environment is conveyed to Rab27a, and is subsequent recruitment to melanosomes remains to be clarified.
Oral history interview with Mary Astor, 1971
Publisher: name: Columbia University
Year: 2020
Subjects: Actresses
Motion pictures
Acting
Motion pictures--Production and direction

description: Work in early talking pictures, 1930; roles in "The Maltese Falcon," "Dodsworth," "Meet Me In St. Louis," others; atmosphere on sets of films; recollections of work relationships with various other actors, directors; pluses and minuses of studio system
Unconventional Rydberg pumping and applications in quantum information processing
Creators: name: Li, D. X.
name: Shao, X. Q.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a mechanism of unconventional Rydberg pumping (URP) via simultaneously driving each Rydberg atom by two classical fields with different strengths of Rabi frequencies. This mechanism differs from the general Rydberg blockade or Rydberg antiblockade since it is closely related to the ground states of atoms, i.e. two atoms in the same ground state are stable while two atoms in different ground states are resonantly excited. Furthermore, we find the URP can be employed to simplify some special quantum information processing tasks, such as implementation of a three-qubit controlled phase gate with only a single Rabi oscillation, preparation of two- and three-dimensional steady-state entanglement with two identical atoms, and realization of the autonomous quantum error correction in a Rydberg-atom-cavity system. The feasibility of the above applications is certified explicitly by the state-of-the-art technology.
description: 9 pages, 11 figures. The typos in Eq (2) are corrected
Enhancement of Power System Loading Capacity Through Low Order Robust Control Design
Creators: name: Simfukwe, Dumisani Dunwell
Publisher: name: Imperial College London
Year: 2012

description: Today’s power systems are becoming heavily loaded and operating close to their stability limit. This raises issue of voltage security and small signal stability, which may lead to the system being forced to operate way below its rated capacity. The impact of renewable technology such as wind and other technologies are likely to further strain existing power networks and infrastructure, hence, likely to adversely affect voltage stability of the power network. The intermittency associated with these sources could also adversely affect on the damping of the system’s oscillatory modes. The work presented in this thesis develops techniques for identifying which controls are effective to improve voltage security margins. Using distributed series impedance, a device that can either increase or reduce line impedance, and margin sensitivity, it is shown that voltage stability margin can be effectively enhanced. Validation is performed on a 39 bus system following a major line outage contingency. Ways of improving the accuracy of margin sensitivity with respect to various controls are presented. Techniques for designing controllers to improve system mode damping have been developed. Unlike techniques using predominately state-space method, these which utilise polynomial methods, yield robust controller of low order and whose structure can be pre-specified. Three techniques are presented. The first uses Kharitonov’s theorem and results in bilinear matrix inequality (BMI) stability conditions. The second uses the theory of positive polynomials which results in linear matrix inequality (LMI) conditions for stability. The last uses conic programming to the controller design problem as a two part problem, first involving phase compensation design, then gain tuning. The effectiveness of the techniques is validated by designing controller for an 68 bus test system model.
Chaotic magnetoconvection in a non-uniformly rotating electroconductive fluids
Creators: name: Kopp, M. I.
name: Tur, A. V.
name: Yanovsky, V. V.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We study a new type of magnetoconvection in a nonuniform rotating plasma layer under a constant vertical magnetic field. To describe the weakly nonlinear stage of convection we apply Galerkin-truncated approximation and we obtain the system of equations of Lorentz type. A numerical analysis of these equations shows the presence of chaotic behavior of convective flows. Criteria for the appearance of chaotic motions are found depending on the convection parameters (Rayleigh number $\textrm{Ra}$), magnetic field (Chandrasekhar number $\textrm{Q}$), rotation (Taylor number $\textrm{Ta}$) for the Keplerian angular velocity profile $(\textrm{Ro}=-3/4)$ of the medium.
description: 9 pages, 4 figures, conference
N=2 Heterotic Superstring and its Dual Theory in Five Dimensions
Creators: name: Antoniadis, I.
name: Ferrara, S.
name: Taylor, T. R.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study quantum effects in five dimensions in heterotic superstring theory compactified on K_3 x S_1 and analyze the conjecture that its dual effective theory is eleven-dimensional supergravity compactified on a Calabi-Yau threefold. This theory is also equivalent to type II superstring theory compactified on the same Calabi-Yau manifold, in an appropriate large volume limit. In this limit the conifold singularity disappears and is replaced by a singularity associated to enhanced gauge symmetries, as naively expected from the heterotic description. Furthermore, we exhibit the existence of additional massless states which appear in the strong coupling regime of the heterotic theory and are related to a different type of singular points on Calabi-Yau threefolds.
description: 26 pages, LaTeX
Structural Insight into Antisense Gapmer-RNA Oligomer Duplexes through Molecular Dynamics Simulations
Creators: name: Mallikarjunachari V.N. Uppuladinne
name: Uddhavesh B. Sonavane
name: Deka, Ramesh Ch.
name: Joshi, Rajendra R.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: There is an extensive research carrying out on antisense technology and the molecules entering into clinical trials are increasing rapidly. Phosphorothioate (PS) is a chemical modification in which non-bridged oxygen is replaced with a sulfur, consequently providing resistance against nuclease activity. The 2'-4' conformationaly restricted nucleoside has the structural features of both 2'-O-methoxy ethyl RNA (MOE), which shows good toxicity profile, and locked nucleic acid (LNA), which shows good binding affinity towards the target RNA. These modifications have been studied and suggested that they can be a potential therapeutic agents in antisense therapy. Mipomersen (ISIS 301012), which contains the novel nucleoside modification has been used to target to apolipoprotein (Apo B), which reduces LDL cholesterol by 6-41%. In this study, classical molecular dynamics (MD) simulations were performed on six different antisense gapmer/target-RNA oligomer duplexes (LNA-PS-LNA/RNA, RcMOE-PS-RcMOE/RNA, ScMOE-PS-ScMOE/RNA, MOE-PS-MOE/RNA, PS-DNA/RNA and DNA/RNA) to investigate the structual dynamics, stability and solvation properties. The LNA, MOE nucleotides present in respective duplexes are showing the structure of A-form and the PS-DNA nucleotides resemble the structure of B-form helix with respect to some of the helical parameters. Free energy calculations suggest that the oligomer, which contains LNA binds to the RNA strongly than other modifications as shown in experimental results. The MOE modified nucleotide, which although had a lower binding affinity but higher solvent accessible surface area (SASA) compared to the other modifications, may be influencing the toxicity and hence may be used it in Mipomersen, the second antisense molecule which is approved by FDA.
Additional file 1 of Vestibular rehabilitation therapy on balance and gait in patients after stroke: a systematic review and meta-analysis
Creators: name: Meng, Lijiao
name: Liang, Qiu
name: Yuan, Jianrong
name: Li, Siyi
name: Ge, Yanlei
name: Yang, Jingyi
name: Tsang, Raymond C C
name: Wei, Quan
Publisher: name: figshare
Year: 2023
Subjects: Space Science
Medicine
Biotechnology
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Additional file 1. Preferred Reporting Items for Systematic reviews and Meta-Analysis statement checklist.
Oral history interview with Mary D'Elia, 1986
Publisher: name: Columbia University
Year: 2021
Subjects: High-rise apartment buildings--New York (State)

description: Background: Childhood in Clinton, description of the neighborhood, building projects; Career: President of Clinton Planning Council, member of Community Board, opposition to Manhattan Plaza, distribution of residents in Manhattan Plaza, Meeting with the Board of Estimate, social problems in the community, isolation of Manhattan Plaza residents, current state of the neighborhood, performing artists in the building, tenant application process, reflection on success of project, current community involvement
Numerical methods for Porous Medium Equation by an Energetic Variational Approach
Creators: name: Duan, Chenghua
name: Liu, Chun
name: Wang, Cheng
name: Yue, Xingye
Publisher: name: arXiv
Year: 2018
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We study numerical methods for porous media equation (PME). There are two important characteristics: the finite speed propagation of the free boundary and the potential waiting time, which make the problem not easy to handle. Based on different dissipative energy laws, we develop two numerical schemes by an energetic variational approach. Firstly, based on $f \log f$ as the total energy form of the dissipative law, we obtain the trajectory equation, and then construct a fully discrete scheme. It is proved that the scheme is uniquely solvable on an admissible convex set by taking the advantage of the singularity of the total energy. Next, based on $\frac{1}{2 f}$ as the total energy form of the dissipation law, we construct a linear numerical scheme for the corresponding trajectory equation. Both schemes preserve the corresponding discrete dissipation law. Meanwhile, under some smoothness assumption, it is proved, by a higher order expansion technique, that both schemes are second-order convergent in space and first-order convergent in time. Each scheme yields a good approximation for the solution and the free boundary. No oscillation is observed for the numerical solution around the free boundary. Furthermore, the waiting time problem could be naturally treated, which has been a well-known difficult issue for all the existence methods. Due to its linear nature, the second scheme is more efficient.
description: 40 pages, 6 figures, 6 tables
Dark energy and the Boomerang data
Creators: name: Amendola, Luca
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The recent high-quality Boomerang data allow to test many competing cosmological models. Here I present a seven-parameter likelihood analysis of dark energy models with exponential potential and explicit coupling to dark matter. Such a model is conformally equivalent to a scalar field with non-minimal coupling to gravity. So far, the constraints on a dark energy - dark matter coupling were extremely weak. The Boomerang data constrain the dimensionless coupling $β$ to be smaller than 0.1, an order of magnitude better than previous limits. In terms of the constant $ξ$ of non-minimally coupled theories, this amounts to $ξ<0.01.$ On the other hand, Boomerang has not enough sensitivity to put constraints on the potential slope.
description: seven pages, two figures. Minor revision to match version accepted in Phys. Rev. Lett
title: ADCO, Cart. 186 (11 H 71), f. 0166r
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la Côte-d'Or, C
art. 186 (11 H 71). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la
 Côte-d'Or, Cart. 186 (11 H 71), f. 0166r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-
project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
The D/H ratio at z = 3.57 toward Q 1937-1009
Creators: name: Levshakov, Sergei A.
name: Kegel, Wilhelm H.
name: Takahara, Fumio
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Deuterium abundance re-measurements by Burles and Tytler (1998; hereafter BT) yielded D/H = (3.3 +/- 0.3) 10^{-5} and the robust upper limit D/H < 3.9 10^{-5} from the z_a = 3.572 system toward Q1937-1009. In this new analysis BT adopted multicomponent microturbulent models together with the possibility to vary freely the local continuum level around each HI line to improve the fit. The procedure failed, however, to fit adequately D Ly-beta without recourse to an additional H Ly-alpha contamination at the position of D Ly-beta. We show that this obstacle may be successfully overcome within the framework of the mesoturbulent model accounting (in contrast to the microturbulent approximation) for a correlated structure of the large scale velocity field. Using the same observational data and the original continuum as determined by Tytler et al. (1996), we obtained good fits. The one-component mesoturbulent models provide D/H in the range (3.2 - 4.8) 10^{-5} and the total hydrogen column density N(HI) = (5.6 - 7.0) 10^{17} cm^{-2}. This result is consistent with that found by us from the z_a = 2.504 and z_a = 0.701 systems toward Q1009+2956 and Q1718+4807, respectively. The range for D/H common to all three analyses is D/H = (4.1 - 4.6) 10^{-5}. This value is consistent with standard big bang nucleosynthesis [SBBN] if the baryon-to-photon ratio, η, is in the range 4.2 10^{-10} <= η<= 4.6 10^{-10}, implying 0.0155 <= Ω_b h^2_{100} <= 0.0167.
description: 8 pages, 2 Postscript figures, aaspp4.sty file, submit. ApJ Lett
Chiral physics in the magnetic field with quark confinement contribution
Creators: name: Andreichikov, M. A.
name: Simonov, Yu. A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The standard chiral perturbation theory is known to predict much weaker effects in magnetic field, than found in numerical lattice data. To overcome this disagreement we are using the effective chiral confinement Lagrangian, $L_{ECCL}$, containing both chiral and quark degrees of freedom, in the presence of external magnetic field. Without magnetic fields $L_{ECCL}$ reduces to the ordinary chiral Lagrangian $L_{EC L}$, yielding in the lowest order $O(\partial_μφ)^2$ all known relations, and providing explicit numerical coefficients in the higher $O(p^4, p^6)$ orders. The inclusion of the magnetic field in $L_{ECCL}$ strongly modifies ECL results for chiral condensates, coupling constants $f_π, f_K$ and masses of chiral mesons. The resulting behavior contains the only parameter -- the string tension $σ$, is roughly proportional to $O\left( \frac{eB}σ\right)$ and agrees very well with lattice data. These results show that the magnetic field acts not only on the chiral degrees of freedom $(φ_π)$, but also on quarks in the quark-chiral Lagrangian, which produce much stronger effect.
description: 24 pages, 6 figures
Additional file 1: of Reliability, validity and responsiveness of E-RS:COPD in patients with spirometric asthma-COPD overlap
Creators: name: Nelsen, Linda
name: Lee, Laurie
name: Wu, Wei
name: Lin, Xiwu
name: Murray, Lindsey
name: Pascoe, Steven
name: Leidy, Nancy
Publisher: name: figshare
Year: 2019
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Includes additional text describing the patient sample, the descriptive statistics for the E-RS and wheeze item, and the results of the inter-item correlations, factor analysis and known-groups validity by primary diagnosis. Descriptive statistics for the E-RS and wheeze item scores for Day − 1 and Day 28 and the EFA at Day − 1 for E-RS with and without the wheeze item in the overall population and by primary diagnosis of asthma and COPD are also described. (DOCX 87 kb)
A lattice path integral for supersymmetric quantum mechanics
Creators: name: Catterall, Simon
name: Gregory, Eric
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We report on a study of the supersymmetric anharmonic oscillator computed using a euclidean lattice path integral. Our numerical work utilizes a Fourier accelerated hybrid Monte Carlo scheme to sample the path integral. Using this we are able to measure massgaps and check Ward identities to a precision of better than one percent. We work with a non-standard lattice action which we show has an {\it exact} supersymmetry for arbitrary lattice spacing in the limit of zero interaction coupling. For the interacting model we show that supersymmetry is restored in the continuum limit without fine tuning. This is contrasted with the situation in which a `standard' lattice action is employed. In this case supersymmetry is not restored even in the limit of zero lattice spacing. Finally, we show how a minor modification of our action leads to an {\it exact}, local lattice supersymmetry even in the presence of interaction.
description: 18 pages, 7 figures, 1 reference added, 1 corrected
Papilio ajax Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Papilionidae
Papilio
Papilio ajax

description: Papilio ajax [spec. nov.]
P. E. alis obtuse caudatis concoloribus fuscis: fasciis flavescentibus, angulo ani fulvo.
Habitat in America boreali.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 462, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Moduli Stars
Creators: name: Krippendorf, Sven
name: Muia, Francesco
name: Quevedo, Fernando
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We explore the possibility that (Bose-Einstein) condensation of scalar fields from string compactifications can lead to long-lived compact objects. Depending on the type of scalar fields we find different realisations of star-like and solitonic objects. We illustrate in the framework of type~IIB string compactifications that closed string moduli can lead to heavy microscopic stars with masses of order $\mathcal{V}^αM_{\rm Planck}$, $α=1,3/2,5/3$ where $\mathcal{V}$ is the volume of the extra dimensions. Macroscopic compact objects from ultra-light string axions are realised with masses of order $e^{\mathcal{V}^{2/3}}M_{\rm Planck}.$ Q-ball configurations can be obtained from open string moduli whereas the closed string sector gives rise to a new class of solutions, named PQ-balls, that arise in the two-field axion-modulus system. The stability, the potential for the formation, and the observability of moduli stars through gravitational waves are discussed. In particular we point out that during the early matter phase given by moduli domination, density perturbations grow by a factor $\mathcal{V}^β$ with $β>2$ and non-linear effects cannot be neglected.
Extreme scattering events and Galactic dark matter
Creators: name: Walker, Mark
name: Wardle, Mark
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Extreme Scattering Events (ESEs) are attributed to radio-wave refraction by a cloud of free-electrons crossing the line-of-sight. We present a new model in which these electrons form the photo-ionized 'skin' of an underlying cool, self-gravitating cloud in the Galactic halo. In this way we avoid the severe over-pressure problem which afflicts other models. The UV flux in the Galactic halo naturally generates electron densities of the right order. We demonstrate, for the first time, a good reproduction of the prototypical ESE in the quasar 0954+658. The neutral clouds are a few AU in radius and have masses less than about 10^{-3} solar. The observed rate of ESEs implies that a large fraction of the mass of the Galaxy is in this form.
description: 5 pp incl 3 figs, LaTeX, uses aas2pp4.sty. Minor revisions. ApJ Letters in press
Factors Influencing the Energy Consumption of High Speed Rail and Comparisons with other Modes
Creators: name: Watson, Robert
Publisher: name: Imperial College London
Year: 2012

description: High speed rail is increasingly viewed as an effective solution to the inter-city passenger transportation challenge of the 21st century due to its ability to significantly increase capacity and reduce journey times between city centres. The motivation behind this thesis is to try to establish whether high speed rail is an efficient mode of transport in terms of operational, traction energy consumption and associated carbon dioxide emissions, and to investigate scope for its improvement. A computational model is developed and validated against existing data and simulations are carried out to estimate the energy consumption of a modern, European high speed train, labelled the HS2 reference train, running on the UK's proposed High Speed Two (HS2) line between London and Birmingham. Investigations are conducted to quantify the effects of different parameters on the operational energy consumption of the line according to a defined Key Performance Indicator. Comparisons are made with the car and domestic air in terms of primary energy consumption, carbon dioxide emissions and journey time. Further simulations are conducted of a Class 390 'Pendolino' train running on the existing West Coast Main Line route between London and Birmingham and comparisons are made with the HS2 reference train, again with reference to the Key Performance Indicator and journey time. In the final part of the thesis simulations are carried out of three different vehicle types running on the HS2 route, which could be considered as alternatives to the HS2 reference train. Analysis is undertaken to determine key areas of vehicle design which contribute to the minimizing of the operational energy consumption and carbon dioxide emissions of high speed rail.
Recommendations for weakly coupled physical- biogeochemical data assimilation. Deliverable report 4.1 of project H2020 SEAMLESS (grant 101004032)
Creators: name: Nerger, Lars
name: Brasseur, Pierre
name: Popov, Michail
name: Skakala, Jozef
name: Teruzzi, Anna
name: Cossarini, Gianpiero
Publisher: name: Zenodo
Year: 2024

description: Deliverable report of the project H2020 SEAMLESS (grant 101004032).

The scope of this document is (i) to report on the developments of weakly coupled ensemble assimilation methods and assimilation experiments performed in Work Package 4 (Task 4.1) of SEAMLESS, and (ii) to provide methodological recommendations to perform weakly coupled physical-biogeochemical data assimilation in the CMEMS MFC 3D domains.
Structural Studies on Microneme proteins from Toxoplasma gondii
Creators: name: Liew, Lloyd
Publisher: name: Imperial College London
Year: 2012

description: Toxoplasma gondii is a polyxenous parasite of the phylum Apicomplexa and the etiological agent of the coccidian disease Toxoplasmosis. Toxoplasma gondii is characterized by its unique gliding motility as well as its ability to infect virtually all nucleated cells. The micronemes are a group of secretory organelles that contribute to the ability of the parasite to recognize the surface of the host-cell prior to parasite invasion via the secretion of adhesive protein complexes. Previous attempts at obtaining structural data for several microneme proteins from Toxoplasma gondii such as microneme protein TgMIC 2, 3 and 4 have so far been unsuccessful due to the inability to produce soluble protein samples using the prokaryotic expression system, Escherichia coli. This work is focussed upon the adaptation of a eukaryotic expression system, Pichia pastoris, to producing Apicomplexan microneme proteins which can cause problems in prokaryotic expression systems due to its eukaryotic origin as well as its high cysteine content. Modifications to the fermenter medium and standard screening protocols allowed for the expression of microneme protein domain constructs in Pichia pastoris with yields ranging from 0.1 to 1.2 mg/L in fermenter culture. Soluble protein samples were produced for several constructs expressed in Pichia pastoris including full length samples of TgMIC3 and TgMIC4 as well as the TSR56 pair in TgMIC2. In addition, isotopically enriched soluble and folded protein samples were successfully produced with a yield of 0.02 to 0.12 mg/L and were successfully subjected to analysis via 2D NMR. Full length TgMIC4 was also successfully crystallized and resulted in crystals which diffracted to 8.0Å. Pichia pastoris has been successful in producing soluble microneme protein samples and has the potential to alleviate the long-standing bottleneck in our efforts to understand the mechanisms involved in Toxoplasma gondii host-cell invasion.
title: AN, Registre des écrous du Châtelet, Y5266, f. p1000625
Creators: name: Claustre, Julie
name: Nationales, Archives
name: Archives Nationales
name: Claustre, Julie
name: ArchivesNationales/J.CLAUSTRE/H.REGAZZI/2020
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Châtelet
subject: registre
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Registre des écrous du Châtelet, Archives Nationales, Y5266. Numérisation en mode image.
description: Bibliographic citation: Archives Nationales, Registre des écrous du Châtelet, Y5266, f. p1000625
Recommendations for weakly coupled physical- biogeochemical data assimilation. Deliverable report 4.1 of project H2020 SEAMLESS (grant 101004032)
Creators: name: Nerger, Lars
name: Brasseur, Pierre
name: Popov, Michail
name: Skakala, Jozef
name: Teruzzi, Anna
name: Cossarini, Gianpiero
Publisher: name: Zenodo
Year: 2023

description: Deliverable report of the project H2020 SEAMLESS (grant 101004032). The scope of this document is (i) to report on the developments of weakly coupled ensemble assimilation methods and assimilation experiments performed in Work Package 4 (Task 4.1) of SEAMLESS, and (ii) to provide methodological recommendations to perform weakly coupled physical-biogeochemical data assimilation in the CMEMS MFC 3D domains.
Charge Screening in the Finite Temperature Schwinger Model
Creators: name: Grignani, G.
name: Semenoff, G.
name: Sodano, P.
name: Tirkkonen, O.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute the effective action and correlators of the Polyakov loop operator in the Schwinger model at finite temperature and discuss the realization of the discrete symmetries that occur there. We show that, due to nonlocal effects of massless fermions in two spacetime dimensions, the discrete symmetry which governs the screening of charges is spontaneously broken even in an effective one-dimensional model, when the volume is infinite. In this limit, the thermal state of the Schwinger model screens an arbitrary external charge; consequently the model is in the deconfined phase, with the charge of the deconfined fermions completely screened. In a finite volume we show that the Schwinger model is always confining.
description: 27 pages, latex, no figures. References addded and some misprints corrected
Reduced graphene oxide-polyaniline nanocomposite as an efficient adsorbent for solid phase extraction of Co2+ followed by electrothermal atomic absorption spectrometry
Creators: name: Somayeh Karandish
name: Chamsaz, Mahmoud
name: Zavar, Mohammad Hossein Arbab
name: Gheibi, Mohammad
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: An efficient adsorbent, reduced graphene oxide-polyaniline (rGO-PANI) nanocomposite was used for solid phase extraction and pre-concentration of ultra-trace levels of Co2+ in different real samples. Graphene oxide (GO) was synthesised from graphite by Hummer method and after reduction by NaBH4, it was modified with poly-aniline to produce rGO-PANI. Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and electron–dispersive X-ray spectroscopy (EDS) were used for characterisation of the synthesised rGO-PANI nanocomposite. The main parameters affecting the extraction efficiency such as pH, amounts of adsorbent, extraction and desorption times were optimised by response surface methodology based on central composite design (RSM-CCD). According to the results, pH 8, 5.8 mg rGO-PANI, 15 min extraction time and 8 min desorption time were selected as the optimum values. Under the optimum conditions, the calibration curve was linear in the range of 0.05–0.6 µg L−1 for Co2+. The relative standard deviation (%RSD) for seven replicate analysis of 0.2 µg L−1 Co2+ was 3.2% and the limit of detection (LOD) was 0.017 µg L−1 Co2+ (n = 7). The certified reference material, CRM-TMDW, was successfully used to validate the accuracy of the proposed method and finally, this technique was applied for determination of ultra-trace levels of Co2+ in different water and food samples.
Gamma-Ray Bursts From Neutron Star Phase Transitions
Creators: name: Fryer, C. L.
name: Woosley, S. E.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The phase-transition induced collapse of a neutron star to a more compact configuration (typically a ``strange'' star) and the subsequent core bounce is often invoked as a model for gamma-ray bursts. We present the results of numerical simulations of this kind of event using realistic neutrino physics and a high density equation of state. The nature of the collapse itself is represented by the arbitrary motion of a piston deep within the star, but if any shock is to develop, the transition, or at least its final stages, must occur in less than a sonic time. Fine surface zoning is employed to adequately represent the acceleration of the shock to relativistic speeds and to determine the amount and energy of the ejecta. We find that these explosions are far too baryon-rich (ejected Mass > 0.01 solar masses) and have much too low an energy to explain gamma-ray bursts. The total energy of the ejecta having relativistic lorentz factors > 40 is less than 10^46 erg even in our most optimistic models (deep bounce, no neutrino losses or photodisintegration). However, the total energy of all the ejecta, mostly mildly relativistic, is roughly 10^51 erg and, if they occur, these events might be observed. They would also contribute to Galactic nucleosynthesis, especially the r-process, even though the most energetic layers are composed of helium and nucleons, not heavy elements.
description: 16 pages, 4 figures, 1 table, AASTeX, Accepted in ApJ
Some New Results in Sequential Monte Carlo
Creators: name: Martin, James Stewart
Publisher: name: Imperial College London
Year: 2012

description: Sequential Monte Carlo (SMC) methods have been well studied within the context of performing inference with respect to partially observed Markov processes, and their use in this context relies upon the ability to evaluate or estimate the likelihood of a set of observed data, given the state of the latent process. In many real-world applications such as the study of population genetics and econometrics, however, this likelihood can neither be analytically evaluated nor replaced by an unbiased estimator, and so the application of exact SMC methods to these problems may be infeasible, or even impossible. The models in many of these applications are complex, yet realistic, and so development of techniques that can deal with problems of likelihood intractability can help us to perform inference for many important yet otherwise inaccessible problems; this motivates the research presented within this thesis. The main focus of this work is the application of approximate Bayesian computation (ABC) methodology to state-space models (SSMs) and the development of SMC methods in the context of these ABC SSMs for filtering and smoothing of the latent process. The introduction of ABC here avoids the need to evaluate the likelihood, at the cost of introducing a bias into the resulting filtering and smoothing estimators; this bias is explored theoretically and through simulation studies. An alternative SMC procedure, incorporating an additional rejection step, is also considered and the novel application of this rejection-based SMC procedure to the ABC approximation of the SSM is considered. This thesis will also consider the application of MCMC and SMC methods to a class of partially observed point process (PP) models. We investigate the problem of performing sequential inference for these models and note that current methods often fail. We present a new approach to smoothing in this context, using SMC samplers (Del Moral et al., 2006). This approach is illustrated, with some theoretical discussion, on a doubly stochastic PP applied in the context of finance.