cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Carbide-free bainitic steels for wear and rolling contact fatigue resistant applications
Creators: name: Gola, Adam Marek
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: carbide-free bainite
rolling contact fatigue
abrasion
impact
wear

description: Carbide-free bainitic (CFB) steels are one of the novel solutions for applications requiring high strength with increased toughness. In this work, knowledge about the transformation mechanism and its significance for mechanical properties are summarised. The role of carbon, which partitions after displacive growth of bainitic ferrite, is stressed as the main strengthcontributing factor. Alloy design together with the thermomechanical treatment methods are discussed with the aim of achieving optimal mechanical properties for wear resistance and rolling contact fatigue. The idea of using carbide free bainitic steels for these kinds of applications is not new; however, a straightforward relationship between microstructural features and the ultimate performance has yet to be found. It is believed that the retained austenite fraction, size and morphology are closely related to its mechanical stability, which is crucial in affecting its transformation to martensite. To investigate the evolution of the microstructure, multiple tests were conducted on a variety of CFB steels differing in carbon content to replicate the working conditions in real-life applications. Two-step austempering and sub-zero cooling post-treatment were utilized as ways of reducing excess of blocky retained austenite. Microstructural alterations were observed with use of optical and electron microscopy methods, as well as quantified by X-ray diffraction, including a layer-by-layer method developed specially for this work. The research proves the beneficial role of retained austenite for wear resistance, as CFB specimens outperformed martensitic benchmarks of the same initial hardness - measured mass loss was up to 20-25% lower for bainitic samples. Microstructural defects, such as voids and microcracks, generated in CFB by rolling contact fatigue were identified. The presence of coalesced bainite in high carbon specimens was observed – a feat that has not been reported in the literature before.
description: Ovako AB, SKF AB
A measurement of the tau to mu nu nu branching ratio
Creators: name: Kormos, L.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The tau -> mu nu nu branching ratio has been measured using data collected from 1990 to 1995 by the OPAL detector at the LEP collider. The resulting value of B(tau->mu nu nu) = 0.1734 +/- 0.0009(stat) +/- 0.0005(syst) has been used in conjunction with other OPAL measurements to test lepton universality, yielding the coupling constant ratios g(mu)/g(e) = 1.0005 +/- 0.0043 and g(tau)/g(e) = 1.0031 +/- 0.0047, in good agreement with the Standard Model prediction of unity, and also to determine a value for the Michel parameter eta = 0.004 +/- 0.036. This is subsequently used to find a model-dependent limit of the mass for the charged Higgs boson, m(Higgs) > 1.30 tan(beta), in the Minimal Supersymmetric Standard Model.
description: Invited talk at the Seventh International Workshop on Tau Lepton Physics, (Tau02), Santa Cruz, Ca. USA, Sept. 2002, 10 pages, LaTex, 11 eps figures, PSN tau02_03
Supplementary materials for: Long-term study shows that increasing body size in response to warmer summers is associated with a higher mortality risk in a long-lived bat species
Creators: name: Mundinger, Carolin
name: Scheuerlein, Alexander
name: Kerth, Gerald
Publisher: name: The Royal Society
Year: 2021
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Change in body size is one of the universal responses to global warming, with most species becoming smaller. While small size in most species corresponds to low individual fitness, small species typically show high population growth rates in cross-species comparisons. It is unclear, therefore, how climate-induced changes in body size ultimately affect population persistence. Unravelling the relationship between body size, ambient temperature and individual survival is especially important for the conservation of endangered long-lived mammals such as bats. Using an individual-based 24-year dataset from four free-ranging Bechstein's bat colonies (Myotis bechsteinii), we show for the first time a link between warmer summer temperatures, larger body sizes and increased mortality risk. Our data reveal a crucial time window in June–July, when juveniles grow to larger body sizes in warmer conditions. Body size is also affected by colony size, with larger colonies raising larger offspring. At the same time, larger bats have higher mortality risks throughout their lives. Our results highlight the importance of understanding the link between warmer weather and body size as a fitness-relevant trait for predicting species-specific extinction risks as consequences of global warming.
How do environmental regulations affect investments in biofuel and biofuel R&D?: the case of transgenic trees.
Creators: name: Sedjo, Roger
name: Sedjo, Roger
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agricultural and Food Policy
subject: Environmental Economics and Policy
subject: Research and Development/Tech Change/Emerging Technologies
subject: Biotech
subject: biofuels
subject: biomass
subject: transgenetic
subject: genetic engineering
subject: trees
subject: regulations
subject: litigation
subject: APHIS

description: Genetically engineered or transgenic trees can play a major role in providing the feedstock for an energy sector that relies increasingly on renewable energy. Biomass energy sources such as wood, both in the form of direct combustion and in the production of liquid biofuels for transport, are being viewed as a major energy source of the near future. Worldwide there is a growing emphasis to shift from fossil fuel to renewable energy sources largely in recognition of the GHG emissions associated with fossil fuels. The potential exists for customizing trees to provide energy, both as a feedstock for liquid biofuels and for direct combustion either as raw wood chips or a wood pellets. However, in the U.S. all transgenic plants, including trees, automatically come under regulation and must be deregulated if they are to be grown in large commercial operations. Although there is a process for deregulating transgenic plants through the US Department of Agriculture – Animal Plant Health Inspection Service (APHIS) and other government agencies, the process has become increasingly slow and cumbersome, particularly for perennial plants including trees. Indeed, it is argued that the obstacles to deregulation have been increasing. This paper looks at that situation and identifies some of the elements that contribute to the slowing of the process. It notes some inherent conflicts and social tradeoffs between a timely deregulation process and concerns about environmental obstacles given current legal decisions.
All-order alpha'-expansion of one-loop open-string integrals
Creators: name: Mafra, Carlos R.
name: Schlotterer, Oliver
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Number Theory (math.NT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We present a new method to evaluate the $α'$-expansion of genus-one integrals over open-string punctures and unravel the structure of the elliptic multiple zeta values in its coefficients. This is done by obtaining a simple differential equation of Knizhnik-Zamolodchikov-Bernard-type satisfied by generating functions of such integrals, and solving it via Picard iteration. The initial condition involves the generating functions at the cusp $τ\to i\infty$ and can be reduced to genus-zero integrals.
description: 6 pages, 2 figures, v2: added explanations, removed the appendix, matches published version
The Economic Impact of Drought Tolerant Rice Varieties in South India
Creators: name: Selvaraj, K.N.
name: Pray, Carl
name: Nagarajan, Latha
name: Selvaraj, K.N.
name: Pray, Carl
name: Nagarajan, Latha
Publisher: name: Unknown
Year: 2010
Subjects: Crop Production/Industries
Environmental Economics and Policy

description: Drought is the one of the important factors that limit the productivity of rice in the fragile environments of South India. The existing modern varieties of rice do not perform well under drought stress conditions. Tamil Nadu Agricultural University (TNAU) has used a number of techniques to develop drought tolerant (DT) rice varieties – conventional breeding, molecular breeding and genetic engineering. So far the most advanced varieties from DT programs – PMK 3, PMK 4, and RMD 1- were developed through conventional breeding and molecular breeding. The genetic engineering research program for DT is not active at present. DT varieties are based on crosses of land races and high yielding varieties with white slender grain quality. In this study we likely welfare effects generated by the adoption of DT varieties at the regional level. For this purpose a farm level survey was conducted among the 120 farm households in major drought prone districts of Tamil Nadu 2008 – 09. All the selected farmers were provided seeds of DT cultivars (PMK 3, PMK4, RMD 1) as a part of on-farm trials managed by TNAU Scientists. The farmers also grew land races and other HY cultivars of rice in their lands during the season. The results from the cost of cultivation and returns of DT, existing land races and HYVs indicate that the adoption of DT varieties would bring additional benefit to the farmers to the tune of 32.82 per cent despite increase cost of human labor and manures by 15 percent. There was a significant reduction in the cost of other input such as seed, chemical fertilizer and machine power. Reduction in cost and higher productivity together benefited the farmers as a result total returns and the net gain over 20 percent.
A screen for novel interactions within the vertebrate centriole
Creators: name: Barnabas, Deepak David
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: molecular biology
protein-protein interactions
centriole

description: The centrioles organize the centrosomes and cilia which play a role in cell division, motility, sensing, polarity, trafficking and signalling. There has been an increase in the understanding of centriole composition and function recently. However, the exact assembly mechanism of the centriole at the molecular level is only beginning to be understood. Knowledge of the canonical assembly mechanism is important to understand how centriole dysfunction materialises in the case of some human diseases. The identification of protein-protein interactions (PPIs) can progress our understanding of the assembly process. In this thesis, I follow two approaches towards this objective. First, I conduct a large-scale combinatorial screen of 3025 binary test pairs amongst a subset of 55 vertebrate centriole/centriole associated proteins. The screen detected 28% of the interactions identified already in the literature and further identified 67 novel binary PPIs within the vertebrate centriole. Of these, 13 are likely to be physiologically relevant due to colocalization of the components within the same centriolar sublocation. I then identify the minimal interaction regions (MIRs) of the proteins involved in these binary interactions and validate such interactions in the mammalian cell context. I perform diagnostic pull-down assays of these putative full-length binary protein complexes recombinantly expressed in insect cells with the aim of subjecting the complexes to structural/biophysical studies. Only 1 novel interaction eluted (PLK1-KIF24) robustly as a binary complex. I validate this interaction in-vitro using SEC-MALS and map the binding region further using NMR. In the second approach towards identifying novel PPIs, I attempt to purify literature-predicted putative multi-protein sub-complexes of the centriole. In summary, the main objective of this thesis has been achieved. The novel PPIs identified in this study, especially those with potential physiological relevance present a good starting point for future investigation. Further, the approach taken in this thesis could serve as a framework to explore other subcellular structures.
description: University of Cambridge, Medical Research Council (MRC), Cambridge Cancer Centre
The Incompatibility of Science and Trade at the International Level
Creators: name: Smyth, Stuart
name: Kerr, William A.
name: Phillips, Peter
name: Smyth, Stuart
name: Kerr, William A.
name: Phillips, Peter
Publisher: name: Unknown
Year: 2010
Subjects: subject: International Relations/Trade
subject: international trade
subject: governance
subject: science-based regulation
subject: knowledge management

description: International trade rules based on science are not functioning efficiently. Considerable effort was put forth in the 20th century to enable politics to be removed from the frameworks that governed international trade. Some degree of success was witnessed from these efforts as numerous institutions (i.e. SPS/WTO, IPPC, OECD, Codex) were founded or their roles expanded. These institutions were established on the premise that science-based frameworks were essential to the efficient functioning of international commerce. The first decade of the 21st century would seem to suggest that these institutions are floundering and that the role of science as the basis of international trade rules is on the decline. The evidence of international trade inefficiencies are witnessed in the case of products derived from biotechnology. The most recent example of this is the absolute halt in the international trade of flax from Canada to Europe after the trace detection of a trait that was approved for food and feed use in Canada but not in Europe. Examples of this can also be found in corn, soybeans and rice. The success of international institutions in dealing with transformative technologies such as biotechnology has thus far been rather dismal. This paper focuses on the fundamental causes for the disruption of international trade and endeavours to provide insights into how to move forward.
Weak homology of elliptical galaxies
Creators: name: Bertin, G.
name: Ciotti, L.
name: Del Principe, M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We start by studying a small set of objects characterized by photometric profiles that have been pointed out to deviate significantly from the standard R^{1/4} law. For these objects we confirm that a generic R^{1/n} law, with n a free parameter, can provide superior fits (the best-fit value of n can be lower than 2.5 or higher than 10), better than those that can be obtained by a pure R^{1/4} law, by an R^{1/4}+exponential model, and by other dynamically justified self--consistent models. Therefore, strictly speaking, elliptical galaxies should not be considered homologous dynamical systems. Still, a case for "weak homology", useful for the interpretation of the Fundamental Plane of elliptical galaxies, could be made if the best-fit parameter n, as often reported, correlates with galaxy luminosity L, provided the underlying dynamical structure also follows a systematic trend with luminosity. We demonstrate that this statement may be true even in the presence of significant scatter in the correlation n(L). Preliminary indications provided by a set of "data points" associated with a sample of 14 galaxies suggest that neither the strict homology nor the constant stellar mass--to--light solution are a satisfactory explanation of the observed Fundamental Plane (abridged).
description: 34 pages, 11 figures, accepted by Astronomy and Astrophysics
Digital Democracy: Episode IV -- A New Hope, How a Corporation for Public Software Could Transform Digital Engagement for Government and Civil Society
Creators: name: Gastil, John
name: Davies, Todd
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computers and Society (cs.CY)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences
subject: K.4.1; K.5.2
subject: K.4.1, K.5.2

description: Though successive generations of digital technology have become increasingly powerful in the past twenty years, digital democracy has yet to realize its potential for deliberative transformation. The undemocratic exploitation of massive social media systems continued this trend, but it only worsened an existing problem of modern democracies, which were already struggling to develop deliberative infrastructure independent of digital technologies. There have been many creative conceptions of civic tech, but implementation has lagged behind innovation. This essay argues for implementing one such vision of digital democracy through the establishment of a public corporation. Modeled on the Corporation for Public Broadcasting in the U.S., this entity would foster the creation of new digital technology by providing a stable source of funding to nonprofit technologists, interest groups, civic organizations, government, researchers, private companies, and the public. Funded entities would produce and maintain software infrastructure for public benefit. The concluding sections identify what circumstances might create and sustain such an entity.
description: 17 pages, 1 figure, 2 tables, to appear in Digital Government: Research and Practice (DGOV)
The interpretation of deeds and wills at common law, c. 1536-c. 1616
Creators: name: McCunn, Joanna Hester
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: law
history
interpretation

description: This thesis explores common law approaches to the interpretation of deeds and wills between approximately 1536 and 1616. It identifies the rules and principles used by lawyers to understand these documents, and explores the wider forces that influenced their development. The methodology of the thesis is primarily doctrinal: it is principally based on an examination of contemporary law reports and legal treatises. The thesis demonstrates that common lawyers in this period took a sophisticated approach to the interpretation of private documents. They sought to strike a balance between interpreting a document according to the apparent meaning of its words, and interpreting it according to the writer’s presumed intentions. They also appealed to reason to guide them to the right meaning of a document. Different kinds of document required different approaches to interpretation, due to differences in the nature and purpose of each. This thesis argues that common lawyers’ attitudes to interpretation underwent a significant shift during the second half of the sixteenth century. Lawyers became less willing to prioritise a writer’s intention over the proper signification of the words he had used. They developed a preference for resolving cases in accordance with rules and maxims, or with the authority of previously-judged cases. They also became more anxious about the possibility of misinterpreting a document. These changes took place in a wider context of concern about legal documents, litigation, and legal uncertainty. The interpretation of private documents was an issue that both lawyers and laymen cared about fiercely in this period. This thesis will improve our understanding of legal interpretation in a foundational period for its development in England.
description: The research for this thesis was funded by the Selden Society.
Symmetry-Protected Topological Triangular Weyl Complex
Creators: name: Wang, R.
name: Xia, B. W.
name: Chen, Z. J.
name: Zheng, B. B.
name: Zhao, Y. J.
name: Xu, H.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Weyl points are often believed to appear in pairs with opposite chirality. In this work, we show by first-principles calculations and symmetry analysis that single Weyl phonons with linear dispersion and double Weyl phonons with quadratic dispersion are simultaneously present between two specific phonon branches in realistic materials with trigonal or hexagonal lattices. These phonon Weyl points are guaranteed to locate at high-symmetry points due to the screw rotational symmetry, forming a unique triangular Weyl complex. In sharp contrast to conventional Weyl systems with surface arcs terminated at the projections of a pair of Weyl points with opposite chirality, the phonon surface arcs of the unconventional triangular Weyl complex connect the projections of one double Weyl point and two single Weyl points. Importantly, the phonon surface arcs originating from the triangular Weyl complex are extremely long and span the entire surface Brillouin-zone. Furthermore, there are only nontrivial phonon surface states across the iso-frequency surface, which facilitates their detection in experiments and further applications. Our work not only offers the promising triangular phonon Weyl complex but also provides guidance for exploring triangular Weyl bosons in both phononic and photonic systems.
description: 5 pages, 4 figures
One-pot synthesis of novel ether-linked diisoxazole derivatives via sequential O-propargylation and 1,3-dipolar cycloaddition from 2-bromohomoallylic alcohols
Creators: name: Zhang, Xiao-Lan
name: Wei, Mei-Hong
name: Chen, Jun-Min
name: Liu, Xiao-Ling
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: A simple and efficient, one-pot approach for the synthesis of ether-linked diisoxazole derivatives has been developed through sequential reactions, which includes O-propargylation of 2-bromohomoallylic alcohols with propargyl bromide in the presence of sodium hydride in THF, and 1,3-dipolar cycloaddition by the addition of hydroximinoyl chlorides and triethylamine. This protocol provides some advantages such as high regioselectivity, easy operation and good product yields with a wide scope of substrates under mild conditions.
On the Design, Implementation, and Use of Laziness in R
Creators: name: Goel, Aviral
name: Vitek, Jan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences
subject: D.3

description: The R programming language has been lazy for over twenty-five years. This paper presents a review of the design and implementation of call-by-need in R, and a data-driven study of how generations of programmers have put laziness to use in their code. We analyze 16,707 packages and observe the creation of 270.9 B promises. Our data suggests that there is little supporting evidence to assert that programmers use laziness to avoid unnecessary computation or to operate over infinite data structures. For the most part R code appears to have been written without reliance on, and in many cases even knowledge of, delayed argument evaluation. The only significant exception is a small number of packages which leverage call-by-need for meta-programming.
description: 27 pages, 4 tables, 21 figures
British Intelligence Services in Greece, 1940 - 1947
Creators: name: CAPSASKIS, CONSTANTINE
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: SOE
Greece
Greek Civil War
British Intelligence

description: This dissertation seeks to address two key themes, drawing on archives in Britain, the United States, and Greece. Firstly, it examines the impact of British Intelligence on the Greek war effort, resistance to Axis occupation, and the period after liberation, by examining the changing role of intelligence in each period. During the early part of the war, the Intelligence Services, and in particular the newly founded Special Operations Executive, sought to achieve their aim of stoking resistance in Greece to help the British war effort through a number of operations. The failure of these operations, however, would have a lasting impact on their future work in Greece. After the stunning success of SOE Operation ‘Harling’, British officials in Cairo and London increasingly fostered guerrilla warfare, making their mission in Greece extremely complex. This was particularly true of SOE, which now entered the hazardous world of guerrilla politics even as it was now serving an equally important political and diplomatic role. While relations between the British and EAM (the communist-led National Liberation Front) had initially been cordial, relations soured as the war progressed and post-war ambitions became more pressing. Eventually, the understanding between the two sides broke down completely and, only a few months after the liberation of Greece, the British government was in open conflict with the guerrillas of EAM. This leads on to the second key theme of the dissertation: the ramifications of the involvement of British Intelligence on the Greek Civil War, and in particular the effect of the dual policy followed by the British in Greece, trying to achieve what proved to be mutually exclusive military and political aims. It will also seek to elucidate whether British involvement in Greece helped to exacerbate the conditions in Greece which led to Civil War, an ongoing topic of scholarly and public controversy.
description: Self
INGLIZ TILINI IKKINCHI TIL SIFАTIDА О'QITISHDА АNIMАTSIYА YОNDАSHUVINING NАZАRIY АSОSLАRI
Creators: name: Mаxkаmоv, Ziyоdbеk
Publisher: name: Zenodo
Year: 2025

description: Ingliz tilini ikkinchi til (ЕSL) sifаtidа о‘rgаtishdа аnimаtsiоn yоndаshuv sо‘nggi yillаrdа о‘quvchilаrning fаоlligini оshirish, tushunish vа еslаb qоlish qоbiliyаtini оshirish qоbiliyаti tufаyli kаttа е’tibоr qоzоndi. Ushbu mаqоlаdа kоgnitiv tа'lim nаzаriyаlаri, kоnstruktivistik yоndаshuvlаr vа multimоdаl tа'lim аsоslаri аsоsidа ЕSL tа'limidа аnimаtsiyаdаn fоydаlаnishning nаzаriy аsоslаri о'rgаnilаdi. Muhоkаmа аnimаtsiyа vizuаl vа еshitish о'rgаnish tаmоyillаrigа qаndаy mоs kеlishini, intеrfаоl vа hаmkоrlik muhitini rivоjlаntirishni vа turli xil о'quvchilаr uchun tаbаqаlаshtirilgаn tа'limni qо'llаb-quvvаtlаshini tа'kidlаydi. Sаmаrаli аmаlgа оshirish uchun аsоsiy muаmmоlаr vа strаtеgiyаlаr hаm kо'rib chiqilib, ushbu innоvаtsiоn о'qitish mеtоdоlоgiyаsini hаr tоmоnlаmа tushunish imkоnini bеrаdi.
Reinventing PARP1 inhibition: harnessing virtual screening and molecular dynamics simulations to identify repurposed drugs for anticancer therapeutics
Creators: name: Khalid, Mohammad
name: Alqarni, Mohammed H
name: Foudah, Ahmed I.
name: Al Oraby, Mishary Saad
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Poly (ADP-ribose) polymerase 1 (PARP1) is a nuclear protein that plays a pivotal role in DNA repair and has emerged as a promising target for cancer therapy. Repurposing existing FDA-approved drugs for PARP1 inhibition offers an accelerated route to drug discovery. Here, we present an integrated approach to drug repurposing for PARP1 inhibition while utilizing an integrated approach involving structure-based virtual screening and molecular dynamics (MD) simulations. First, a curated library of 3648 FDA-approved drugs from DrugBank was screened to identify potential candidates capable of binding to the PARP1. Our study reveals a subset of drug molecules with favorable binding profiles and stable interactions within the PARP1 active site. The standout candidate, Nilotinib, was selected based on its drug profile and subjected to a detailed analysis, including interaction studies and 500 ns all-atom MD simulations. By integrating multiple computational approaches, we provide a rational framework for the selection of Nilotinib, demonstrating its PARP1 binding features and potential for therapeutic development after further experimentation. This study highlights the power of computational methods in accelerating drug repurposing efforts, offering an efficient strategy for identifying novel therapeutic options for PARP1-associated diseases.
Il fantastico nella narrativa breve di Ángel Olgoso
Creators: name: Remorini, Paolo
Publisher: name: Zenodo
Year: 2011
Subjects: Ángel Olgoso
Microrrelatos
Literatura Fantástica

description: Inquadramento e studio dei temi e dei procedimenti narrativi dei racconti brevi dello scrittore spagnolo Angel Olgoso all'interno della tradizione letteraria fantastica
Additional file 3 of Genome-wide identification of Brassicaceae B-BOX genes and molecular characterization of their transcriptional responses to various nutrient stresses in allotetraploid rapeseed
Creators: name: Zheng, Li-wei
name: Ma, Sheng-jie
name: Zhou, Ting
name: Yue, Cai-peng
name: Hua, Ying-peng
name: Huang, Jin-yong
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 3: Figure S3. Identification and characterization of conserved domains in BBXs in pfam database. Figure S3–1 Identification and characterization of the conserved domains in BnaBBXs. Figure S3–2 Identification and characterization of the conserved domains in BoBBXs. Figure S3–3 Identification and characterization of the conserved domains in BrBBXs. Figure S3–4 Identification and characterization of the conserved domains in CrBBXs. Figure S3–5 Identification and characterization of the conserved domains in CsBBXs. Figure S3–6 Identification and characterization of the conserved domains in BnBBXs. Figure S3–7 Identification and characterization of the conserved domains in BjBBXs. Figure S3–8 Identification and characterization of the conserved domains in BcBBXs.
Efficiency Differentials in Peasant Agriculture and TIJ.eir Implications for Development Policies
Creators: name: Shapiro, Kenneth H.
name: Shapiro, Kenneth H.
Publisher: name: Unknown
Year: 1977
Subjects: Agribusiness
Agricultural and Food Policy
Agricultural Finance

description: This paper reanalyzes the theoretical and enpirical work on allocative efficiency in traditional agriculture and presents a new study of technical efficiency among Tanzanian cotton farmers. The theoretical argtents are shown to apply primarily in a competitive context that differs significantly from that in which peasant faros operate. Reanalysis of earlier empirical studies shows that, on average, the marginal value products of inputs differ by more than 40 per cent fro~ the marginal factor costs to which they should be equated under allocative efficiency. Ou~ o~-n. study among Tanzanian cotton farners in Geita District reveals that output could be increased by 51 per cent if all farmers achieved the s=e levels of technical efficiency that were achieved by the best fa=ers in the sample with the same input:s and technologies. These results indicate that the efficiency hypothesis may not be applicable to much of peasant agriculture and that developn2nt policies might fruitfully place nore emphasis an raising large numbers of farmers closer to the relatively high efficiency levels achieved by sona of their neighbors.
CDM, Feedback and the Hubble Sequence
Creators: name: Sommer-Larsen, Jesper
name: Gotz, Martin
name: Portinari, Laura
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have performed TreeSPH simulations of galaxy formation in a standard LCDM cosmology, including effects of star formation, energetic stellar feedback processes and a meta-galactic UV field, and obtain a mix of disk, lenticular and elliptical galaxies. The disk galaxies are deficient in angular momentum by only about a factor of two compared to observed disk galaxies. The stellar disks have approximately exponential surface density profiles, and those of the bulges range from exponential to r^{1/4}, as observed. The bulge-to-disk ratios of the disk galaxies are consistent with observations and likewise are their integrated B-V colours, which have been calculated using stellar population synthesis techniques. Furthermore, we can match the observed I-band Tully-Fisher (TF) relation, provided that the mass-to-light ratio of disk galaxies, (M/L_I), is about 0.8. The ellipticals and lenticulars have approximately r^{1/4} stellar surface density profiles, are dominated by non-disklike kinematics and flattened due to non-isotropic stellar velocity distributions, again consistent with observations.
description: 6 pages, incl. 4 figs. To appear in the proceedings of the EuroConference "The Evolution of Galaxies: II - Basic Building Blocks", Ile de La Reunion (France), 16-21 October 2001 (Slightly updated version). A much more comprehensive paper about this work with links to pictures of some of the galaxies can be found at http://babbage.sissa.it/abs/astro-ph/0204366
THE CASE FOR LIMITED TRACTORIZATION FOR AGRICULTURAL DEVELOPMENT IN A LABOUR-ABUNDANT ECONOMY
Creators: name: Mandal, Goutam
name: Mandal, Goutam
Publisher: name: Unknown
Year: 1977
Subjects: Agribusiness
Agricultural Finance
Labor and Human Capital

description: The purpose of this paper is to assess the role of limited tractorization in agricultural development on the basis of data collected through a field survey in the district of Shahabad, Bihar, India which was conducted during 1973-74 1 . It is believed that in a less developed economy where labour is abundant and capital is scarce mechanization (specifically tractorization) in farming would be contrary to the principle of factor proportion and as such would be wasteful. Even if tractorization proves more profitable than animal-operated farming it may be socially undesirable in so far as it leads to displacement and consequent underutilization of human labour. The study attempts to examine how far this actually happens and also the possibility of counter-acting the displacement of human labour by an appropriate combination of tractor operations with manual operations on the basis of custom-arrangement.
Study of the intracellular trafficking of the pre-T-cell receptor and its role in T-cell lineage commitment
Creators: name: Smid, Andrei Iosif
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: T-cell
T-cell development
Pre-T-cell receptor
Trafficking
TCR signalling
γδ-TCR
OP9-DL1 co-culture
hematopoietic stem cells
BioID2

description: T-cell development is a complex multi-step process, driving the maturation of hematopoietic stem cells into fully functional mature T-cells that play a major role in the adaptive immune response against pathogens. This developmental process is regulated by a series of checkpoints in which the signalling capacity of the T-cell antigen receptor (TCR) is tested. One such checkpoint is the generation of the clonotypic chains of the two TCR variants (αβ-TCR or γδ-TCR) by V(D)J recombination. Importantly, the TCRα chain is rearranged only after correct TCRβ expression, which requires the latter chain to pair with a surrogate invariant pre-Tα chain to form the pre-TCR complex. While both TCR variants activate the same signalling pathway, they commit the T cells to distinct functional lineages. Insight into how thymocytes are nonetheless able to distinguish between these two signals is crucial to our fundamental understanding of T-cell development and how it might be manipulated therapeutically. Pertinently, the pre-TCR is undetectable at the cell surface, unlike the γδ TCR which is primarily located at the plasma membrane. In this thesis, I aim to investigate whether the distinct intracellular localisation of the pre-TCR provides a mean for this signal to be distinguished from that of the γδ-TCR. Through the reconstitution of pre-TCR expression in a non-immune cell, I show that although the pre-TCR can in fact translocate to the cell surface, it is rapidly removed via clathrin-mediated endocytosis and transported to lysosomes. The use of a non-immune cell permits the study of pre-TCR trafficking in the absence of other signalling components and demonstrates that this intracellular localisation of the pre-TCR is intrinsic to the receptor. Using a panel of truncated and engineered pre-TCR, I demonstrate that the absence of a second Ig domain in the extracellular domain of the pre-Tα chain promotes the rapid endocytosis of the receptor. In a thymocyte-OP9-DL1 co-culture system, I show that recombination-deficient thymocytes expressing a pre-TCR variant lacking the TCRβ variable domain is sufficient to drive cells through the TCRβ-selection checkpoint and give rise to double positive cells. Likewise, wild type thymocytes over-expressing the pre-TCR or a receptor with a fused TCRα variable domain may push thymocytes down the γδ-lineage. Finally, I employ a biotin proximity-labelling assay to screen for binding partners of the pre-TCR that might mediate its internalisation. Using this method, I identify TMEM131, a novel protein with an unknown function and characterise some of its biochemical and cell biological properties.
description: This work was funded by the Wellcome Trust.
PROSPECTS AND PROBLEMS OF A COMMON AGRICULTURAL POLICY AMONG WEST AFRICAN STATES
Creators: name: Akinwumi, J.A.
name: Adegeye, A.J.
name: Akinwumi, J.A.
name: Adegeye, A.J.
Publisher: name: Unknown
Year: 1977
Subjects: Agricultural and Food Policy
International Development

description: In Europe, America, Africa and Asia, the Twentieth Century has witnessed movements towards economic unions and/or common trading arrangements. The fact that early movements at common trading policies were among advanced countries, indicate that even economies at such advanced stages of development see ample benefits to be derived from such associations. The early theories of economic co-operation centred on trade creation and trade diversion are said to be static and are therefore inapplicable to the situation in developing countries. This is due in most cases to their low volume of trade in the world and even between the developing states themselves. Hence economic co-operation here is seen in the light of its contribution to economic growth and/or structural transformation of these developing countries. Thus alliances like those for cocoa and coffee are seen as a means of obtaining high export prices to provide the foreign exchange necessary for economic development.
Electronic response and bandstructure modulation of carbon nanotubes in a transverse electrical field
Creators: name: Li, Yan
name: Rotkin, Slava V.
name: Ravaioli, Umberto
Publisher: name: arXiv
Year: 2002
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The electronic properties of carbon nanotubes in a uniform transverse field are investigated within a single orbital tight-binding model. For doped nanotubes, the dielectric function is found to depend not only on symmetry of the tube, but also on radius and Fermi level position. Bandgap opening/closing is predicted for zigzag tubes, while it is found that armchair tubes always remain metallic, which is explained by the symmetry in their configuration. The bandstructures for both types are considerably modified when the field strength is large enough to mix neighboring subbands.
description: Accepted for publication in Nanoletters, 8 pages, 3 figures
Spectrum Results with Kogut-Susskind Quarks
Creators: name: Toussaint, Doug
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: I summarize recent developments in spectrum calculations using Kogut-Susskind quarks. Theoretical developments include one-loop computations with improved actions. I present some recent simulation results, mostly from a MILC collaboration project using three flavors. Effects of dynamical quarks are clearly seen in the isovector 0++ meson propagator and in the mass ratio ``J''.
description: 6 pages, contribution to Lattice2001(plenary) figures resized, reference added
Development of Magnetic Resonance Spectroscopic Imaging Methods to Assess Tumour Metabolism
Creators: name: Kreis, Felix Karl
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Magnetic Resonance Imaging
Cancer Metabolism
Deuterium Metabolic Imaging
Hyperpolarization

description: Proton detection of hyperpolarized low gamma nuclei. Hyperpolarized molecules labelled with low gamma nuclei such as 15N and 13C have been proposed as magnetic resonance spectroscopic imaging (MRSI) agents for investigating metabolism, perfusion and pH in tumours. However, the sensitivity of direct detection is limited by the low gyromagnetic ratios of these nuclei. Sensitivity can be increased by transferring the hyperpolarization to spin coupled protons provided that there is not significant polarization loss during the transfer. To exploit both the slow relaxation offered by storing the hyperpolarization in the low gamma nucleus and the higher sensitivity of 1H detection, polarization transfer pulse sequences for full and partial transfer of polarization were developed. The possible sensitivity improvement with those MRSI pulse sequences was evaluated in experiments and simulations using hyperpolarized [1-13C]pyruvate, [2-13C]pyruvate, [1-13C]lactate and [15N2]urea. Glycolytic flux measurements in vivo using 2H magnetic resonance spectroscopic imaging. Tumour cells frequently show high rates of aerobic glycolysis, which provides the glycolytic intermediates needed for the increased biosynthetic demands of rapid cell growth and proliferation. These high rates of glycolysis have enabled disease detection and treatment response monitoring using Positron Emission Tomography measurements of 2-([18F]fluoro)-2- deoxy-D-glucose uptake (FDG-PET) and 13C magnetic resonance spectroscopic imaging of hyperpolarized [1-13C]pyruvate metabolism. However, neither of these techniques allows quantitative mapping of metabolic fluxes. A fast 3D deuterium MRSI sequence for dynamic imaging of [6,6’-2H2]glucose metabolism was developed and used to map glycolytic flux in a murine tumour model, demonstrating heterogeneity in glycolytic rate an early decrease following treatment.
description: This work was funded by a European Union’s Horizon 2020 Research and Innovation Program under Marie Sklodowska-Curie grant agreement no. 642773 (EUROPOL).
GeospatRE: extraction and geocoding of spatial relation entities in textual documents
Creators: name: Syed, Mehtab Alam
name: Arsevska, Elena
name: Roche, Mathieu
name: Teisseire, Maguelonne
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Spatial information extraction from textual documents and its accurate geo-referencing are important steps in epidemiology, with many applications such as outbreak detection and disease surveillance and control. However, inaccuracy in extraction of such geospatial information will result into inaccurate location identification, which in consequence may produce erroneous information for outbreak investigation and disease surveillance. One of the problems is the extraction of geospatial relations associated with spatial entities in the text documents. In order to identify such geospatial relations, we categorized them into three major relations: 1) Level-1, e.g. center, north, south; 2) Level-2, e.g. nearby, border; 3) Level-3, e.g. distance from spatial entities e.g. 30 km, 20 miles, 100 m, etc., respectively. This work introduces a novel approach for extracting and georeferencing spatial information from textual documents for accurate identification of geospatial relations associated with spatial entities to enhance outbreak monitoring and disease surveillance. We propose a two-step methodology: (i) Extraction of geospatial relations associated with spatial entities, using a clause-based approach, and (ii) Geo-referencing of geospatial relations associated with spatial entities in order to identify the polygon regions, using a custom algorithm to slice or derive the geospatial relation regions from the place name and their geospatial relations. The first step is evaluated with a disease news article dataset consisting of event information and obtaining a precision of 0.9, recall of 0.88 and F-Score of 0.88 respectively. The second step entails using a qualitative evaluation of shapes by end-users. Promising results are obtained for the experiments in second step.
Additional file 5 of Genome-wide identification of Brassicaceae B-BOX genes and molecular characterization of their transcriptional responses to various nutrient stresses in allotetraploid rapeseed
Creators: name: Zheng, Li-wei
name: Ma, Sheng-jie
name: Zhou, Ting
name: Yue, Cai-peng
name: Hua, Ying-peng
name: Huang, Jin-yong
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 5: Figure S5. Synteny of BBX genes in each Brassicaceae genome. Figure S5–1 Synteny of AtBBX genes in A. thaliana genome. Figure S5–2 Synteny of BnaBBX genes in B. napus genome. Figure S5–3 Synteny of BoBBX genes in B. oleracea genome. Figure S5–4 Synteny of BrBBX genes in B. rapa genome. Figure S5–5 Synteny of CrBBX genes in C. rubella genome. Figure S5–6 Synteny of CsBBX genes in C. sativa genome. Figure S5–7 Synteny of BnBBX genes in B. nigra genome. Figure S5–8 Synteny of BjBBX genes in B.juncea genome. S109, C668, C1065 and C306 respectively indicates Super_scaffold_109_3169392_4351964_52914_567609, Contig668_1_483987, Contig1065 and Contig306 in the B.juncea genome. Figure S5–9 Synteny of BcBBX genes in B. carinata genome. J0021.1, J1585.1, J1599.1 and J1604.1 respectively indicates JAAMPC010000021.1, JAAMPC0100001585.1, JAAMPC0100001599.1 and JAAMPC0100001604.1 in the B. carinata genome.
Variants of epigroups and primary conjugacy
Creators: name: Borralho, Maria
name: Kinyon, Michael
Publisher: name: arXiv
Year: 2019
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20M07

description: In a semigroup $S$ with fixed $c\in S$, one can construct a new semigroup $(S,\cdot_c)$ called a \emph{variant} by defining $x\cdot_c y:=xcy$. Elements $a,b\in S$ are \emph{primarily conjugate} if there exist $x,y\in S^1$ such that $a=xy, b=yx$. This coincides with the usual conjugacy in groups, but is not transitive in general semigroups. Araújo \emph{et al.} proved that transitivity holds in a variety $\mathcal{W}$ of epigroups containing all completely regular semigroups and their variants, and asked if transitivity holds for all variants of semigroups in $\mathcal{W}$. We answer this affirmatively as part of a study of varieties and variants of epigroups.
description: 7 pages; v2: stylistic changes suggested by the referee