cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Novel measurement system for respiratory aerosols and droplets in indoor environments
Creators: name: Lommel, Michael
name: Froese, Vera
name: Sieber, Moritz
name: Jentzsch, Marvin
name: Bierewirtz, Tim
name: Hasirci, Ümit
name: Rese, Tim
name: Seefeldt, Josef
name: Schimek, Sebastian
name: Kertzscher, Ulrich
name: Paschereit, Christian Oliver
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: aerosol
subject: infection transmission
subject: measurement system
subject: respiratory droplets
subject: virus spread
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The SARS-CoV-2 pandemic has created a great demand for a better understanding of the spread of viruses in indoor environments. A novel measurement system consisting of one portable aerosol-emitting mannequin (emitter) and a number of portable aerosol-absorbing mannequins (recipients) was developed that can measure the spread of aerosols and droplets that potentially contain infectious viruses. The emission of the virus from a human is simulated by using tracer particles solved in water. The recipients inhale the aerosols and droplets and quantify the level of solved tracer particles in their artificial lungs simultaneously over time. The mobile system can be arranged in a large variety of spreading scenarios in indoor environments and allows for quantification of the infection probability due to airborne virus spreading. This study shows the accuracy of the new measurement system and its ability to compare aerosol reduction measures such as regular ventilation or the use of a room air purifier.
Making systems of Super Earths by inward migration of planetary embryos
Creators: name: Cossou, Christophe
name: Raymond, Sean N.
name: Pierens, Arnaud
Publisher: name: arXiv
Year: 2013
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Using N-body simulations with planet-disk interactions, we present a mechanism capable of forming compact systems of hot super Earths such as Kepler 11. Recent studies show that outward migration is common in the inner parts of radiative disks. However we show that two processes naturally tip the balance in favor of inward migration. First the corotation torque is too weak to generate outward migration for planetary embryos less massive than $4\mearth$. Second, system of multiple embryos generate sustained non-zero eccentricities that damp the corotation torque and again favor inward migration. Migration and accretion of planetary embryos in realistic disks naturally produce super Earths in resonant chains near the disk inner edge. Their compact configuration is similar to the observed systems.
description: 4 pages, 3 figures, to appear in the Proceedings of IAU Symp. 299: Exploring the Formation and Evolution of Planetary Systems (Victoria, Canada)
Doping influence of spin dynamics and magnetoelectric effect in hexagonal Y$_{0.7}$Lu$_{0.3}$MnO$_{3}$
Creators: name: Tian, W.
name: Tan, Guotai
name: Liu, Liu
name: Zhang, Jinxing
name: Winn, Barry
name: Hong, Tao
name: Fernandez-Baca, J. A.
name: Zhang, Chenglin
name: Dai, Pengcheng
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We use inelastic neutron scattering to study spin waves and their correlation with the magnetoelectric effect in Y$_{0.7}$Lu$_{0.3}$MnO$_3$. In the undoped YMnO$_3$ and LuMnO$_3$, the Mn trimerization distortion has been suggested to play a key role in determining the magnetic structure and the magnetoelectric effect. In Y$_{0.7}$Lu$_{0.3}$MnO$_3$, we find a much smaller in-plane (hexagonal $ab$-plane) single ion anisotropy gap that coincides with a weaker in-plane dielectric anomaly at $T_N$. Since both the smaller in-plane anisotropy gap and the weaker in-plane dielectric anomaly are coupled to a weaker Mn trimerization distortion in Y$_{0.7}$Lu$_{0.3}$MnO$_3$ comparing to YMnO$_3$ and LuMnO$_3$, we conclude that the Mn trimerization is responsible for the magnetoelectric effect and multiferroic phenomenon in Y$_{1-y}$Lu$_{y}$MnO$_{3}$.
description: 5 pages, 5 figures
Verbesserungsanträge zu dem Gesetzesentwurf, die Verantwortlichkeit der Reichsminister betr.; [1848]
Creators: name: Linde, Justin Timotheus Balthasar von
name: Wichmann, Wilhelm
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2018

description: Kopftitel
Combined seismic and borehole investigation of the deep granite weathering structure—Santa Gracia Reserve case in Chile
Creators: name: Trichandi, Rahmantara
name: Bauer, Klaus
name: Ryberg, Trond
name: Scherler, Dirk
name: Bataille, Klaus
name: Krawczyk, Charlotte M.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: borehole
subject: geophysics
subject: Bayesian inversion
subject: body wave tomography
subject: critical zone
subject: geomorphology
subject: Rayleigh wave
subject: regolith
subject: seismic survey
subject: surface wave tomography
subject: velocity gradient
subject: weathering front
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::550 Geowissenschaften

description: Imaging the critical zone at depth, where intact bedrock transforms into regolith, is critical in understanding the interaction between geological and biological processes. We acquired a 500 m‐long near‐surface seismic profile to investigate the weathering structure in the Santa Gracia National Reserve, Chile, which is located in a granitic environment in an arid climate. Data processing comprised the combination of two seismic approaches: (1) body wave tomography and (2) multichannel analysis of surface wave (MASW) with Bayesian inversion. This allowed us to derive P‐wave and S‐wave velocity models down to 90 and 70 m depth, respectively. By calibrating the seismic results with those from an 87 m‐deep borehole that is crossed by the profile. We identified the boundaries of saprolite, weathered bedrock, and bedrock. These divisions are indicated in the seismic velocity variations and refer to weathering effects at depth. The thereby determined weathering front in the borehole location can be traced down to 30 m depth. The modelled lateral extent of the weathering front, however, cannot be described by an established weathering front model. The discrepancies suggest a more complex interaction between different aspects such as precipitation and topography in controlling the weathering front depth.
Eumerus truncatus Rondani 1868
Creators: name: Sforzi, Alessandra
name: Sommaggio, Daniele
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Eumerus
Eumerus truncatus

description: Eumerus truncatus Rondani, 1868
ORIGINAL DESCRIPTION: 1868d: 575.
TYPE LOCALITY: “ in Sicilia ad Nebrodes [Nebrodi mountains, Sicily (Italy)]”.
TYPE MATERIAL: 1 ♂, holotype (missing left hind-leg) (MZUF: Box 4): Eumerus Mgn / truncatus Rnd., Sicil. / 147 / Madonie / E. truncatus bona sp. Vujić 2014 / Holotype ♂ Eumerus truncatus Rondani, 1869 det. J. van Steenis, 2016.
CURRENT STATUS: junior synonym of Eumerus barbarus (Coquebert, 1804) (Peck 1988: 154, Belcari et al. 1995a: 14); valid species (Steenis 2017: 162).
REMARKS: Rondani (1868d: 575) described Eumerus truncatus from just the male sex, without specifying either the number or the length of the specimens, from material received from F. Minà Palumbo. Steenis et al. (2017: 162) considered the single MZUF male as the holotype.
description: Published as part of Sforzi, Alessandra & Sommaggio, Daniele, 2021, Catalog of the Diptera types described by Camillo Rondani, pp. 1-438 in Zootaxa 4989 (1) on pages 250-251, DOI: 10.11646/zootaxa.4989.1.1, http://zenodo.org/record/4980621
Additional file 1 of Environmental sustainability in endodontics. A life cycle assessment (LCA) of a root canal treatment procedure
Creators: name: Duane, Brett
name: Borglin, Linnea
name: Pekarski, Stephanie
name: Saget, Sophie
name: Duncan, Henry Fergus
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Appendix 1.
Gardenin A decreases neuroinflammation, activates antioxidant response and improves cognitive and motor function in A53T alpha synuclein overexpressing mice
Creators: name: Gladen Kolarsky, Noah
name: Hack, Wyatt
name: Maitra, Urmila
name: Ciesla, Lukasz
name: Gray, Nora
Publisher: name: Oregon Health and Science University
Year: 2023
Subjects: subject: Neurobiology
subject: Cell Biology
subject: Molecular Biology
subject: Parkinson Disease
subject: Cognition
subject: Motor Function
subject: Cognitive Impairment
subject: Gardenin A

description: Oxidative stress and neuroinflammation are widespread in the Parkinson’s disease (PD) brain and contribute to the synaptic degradation and dopaminergic cell loss that result in cognitive impairment and motor dysfunction. The compound Gardenin A (GA) has been shown to activate the NRF2-regulated antioxidant pathway and inhibit the NFkB-regulated pro-inflammatory pathway in a Drosophila model of PD. Here, we evaluate the effects of GA on A53T alpha-synuclein overexpressing (A53TSyn) mice.
Sleep medicine catalogue of knowledge and skills – Revision
Creators: name: Penzel, Thomas
name: Pevernagie, Dirk
name: Bassetti, Claudio
name: Peigneux, Philippe
name: Paunio, Tiina
name: McNicholas, Walter T.
name: Dogas, Zoran
name: Grote, Ludger
name: Rodenbeck, Andrea
name: Cirignotta, Fabio
name: D’Ortho, Marie‐Pia
name: Nobili, Lino
name: Paiva, Teresa
name: Pollmächer, Thomas
name: Riemann, Dieter
name: Zucconi, Marco
name: Hill, Elizabeth A.
name: Arnardottir, Erna‐Sif
name: Parrino, Liborio
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: catalogue of knowledge and skills
subject: Sleep medicine
subject: Sleep Disorders
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The 'catalogue of knowledge and skills' for sleep medicine presents the blueprint for a curriculum, a textbook, and an examination on sleep medicine. The first catalogue of knowledge and skills was presented by the European Sleep Research Society in 2014. It was developed following a formal Delphi procedure. A revised version was needed in order to incorporate changes that have occurred in the meantime in the International Classification of Sleep Disorders, updates in the manual for scoring sleep and associated events, and, most important, new knowledge in sleep physiology and pathophysiology. In addition, another major change can be observed in sleep medicine: a paradigm shift in sleep medicine has taken place. Sleep medicine is no longer a small interdisciplinary field in medicine. Sleep medicine has increased in terms of recognition and importance in medical care. Consequently, major medical fields (e.g. pneumology, cardiology, neurology, psychiatry, otorhinolaryngology, paediatrics) recognise that sleep disorders become a necessity for education and for diagnostic assessment in their discipline. This paradigm change is considered in the catalogue of knowledge and skills revision by the addition of new chapters.
Additional file 2 of Environmental sustainability in endodontics. A life cycle assessment (LCA) of a root canal treatment procedure
Creators: name: Duane, Brett
name: Borglin, Linnea
name: Pekarski, Stephanie
name: Saget, Sophie
name: Duncan, Henry Fergus
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. Appendix 2.
Radiation Pressure on Submerged Mirrors: Implications for the Momentum of Light in Dielectric Media
Creators: name: Mansuripur, Masud
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: Radiation pressure measurements on mirrors submerged in dielectric liquids have consistently shown an effective Minkowski momentum for the photons within the liquid. Using an exact theoretical calculation based on Maxwell's equations and the Lorentz law of force, we demonstrate that this result is a consequence of the fact that conventional mirrors impart, upon reflection, a 180 degree phase-shift to the incident beam of light. If the mirror is designed to impart a different phase, then the effective momentum will turn out to be anywhere between the two extremes of the Minkowski and Abraham momenta. Since all values in the range between these two extremes are equally likely to be found in experiments, we argue that the photon momentum inside a dielectric host has the arithmetic mean value of the Abraham and Minkowski momenta.
description: 6 pages, 3 figures, 10 equations, 11 references
Reduction of dual‐species biofilm after sonic‐ or ultrasonic‐activated irrigation protocols: A laboratory study
Creators: name: Hoedke, Daniela
name: Kaulika, Namira
name: Dommisch, Henrik
name: Schlafer, Sebastian
name: Shemesh, Hagay
name: Bitter, Kerstin
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: antibacterial effectiveness
subject: nonactivated irrigation
subject: root canal disinfection
subject: sonic activation
subject: ultrasonic activation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Aim: To evaluate the antibacterial effect of sonic- and ultrasonic-activated irrigation on bacterial reduction of a dual-species biofilm in root canals compared to nonactivated irrigation in a laboratory study. Methodology: Two hundred and forty extracted human single-rooted maxillary anterior teeth were divided into two main groups (G, n = 120) according to the initial preparation size of the root canal (G1: size 25, 0.06 taper, G2: size 40, 0.06 taper). Root canals were inoculated with Enterococcus faecalis and Streptococcus oralis. After 5 days, G1 received combined instrumentation (up to size 40, 0.06 taper) and irrigation/activation, whereas G2 received solely irrigation/activation protocols. In both groups, irrigation was performed with sodium hypochlorite (NaOCl 1%) or physiological saline (NaCl 0.9%), using nonactivated syringe irrigation, sonic activation (2 x 30 s) or ultrasonic activation (2 x 30 s). Logarithmic reduction factors (LRFs) of colony-forming units were analysed separately for dentine-adherent and planktonic bacteria immediately after irrigation/activation protocols (time-point 1) or after 5 days of further incubation (time-point 2) by analysis of variance (anova) and post hoc tests (Tukey's HSD, t-test). The significance level was set at 0.05. Results: In G1 subgroups (combined instrumentation with irrigation/activation), LRFs were significantly affected by the applied irrigation solution (p < .0001), but not by the activation method (p > .05; anova). In G2 subgroups (solely irrigation/activation), both, irrigant solution and activation, significantly affected LRFs (p < .0001, anova). Sonic activation resulted in significantly higher LRFs than ultrasonic activation (p < .0001) which had significantly greater reductions than nonactivated irrigation (p < .05; Tukey's HSD). At T2, strong bacterial regrowth was observed in all groups; however, a significant bacterial reduction was detected for factors instrumentation, irrigant solution and activation (p < .0001; anova). Similar LRFs were found for dentine-adherent and planktonic bacterial cells in all groups (r = 0.91 at T1, r = 0.8 at T2). Conclusions: In this laboratory study on extracted maxillary anterior teeth high-frequency sonic activation resulted in a greater bacterial reduction compared to ultrasonic activation in groups receiving solely irrigation/activation protocols; however, irrigation using NaOCl and ultrasonic activation also contributed significantly to bacterial reduction compared to the control groups.
Squeezing a thermal mechanical oscillator by stabilized parametric effect on the optical spring
Creators: name: Pontin, A.
name: Bonaldi, M.
name: Borrielli, A.
name: Cataliotti, F. S.
name: Marino, F.
name: Prodi, G. A.
name: Serra, E.
name: Marin, F.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We report the confinement of an optomechanical micro-oscillator in a squeezed thermal state, obtained by parametric modulation of the optical spring. We propose and implement an experimental scheme based on parametric feedback control of the oscillator, which stabilizes the amplified quadrature while leaving the orthogonal one unaffected. This technique allows us to surpass the -3dB limit in the noise reduction, associated to parametric resonance, with a best experimental result of -7.4dB. In a moderately cooled system, our technique can be efficiently exploited to produce strong squeezing of a macroscopic mechanical oscillator below the zero-point motion.
description: 12 pages,6 figures
Eumerus nivipes Rondani 1850
Creators: name: Sforzi, Alessandra
name: Sommaggio, Daniele
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Eumerus
Eumerus nivipes

description: [Eumerus nivipes] Rondani, 1850a: 122.
REMARKS: name that Rondani (1850a: 122) proposed as a synonym of Eumerus exilipes Rondani, 1850 and was not made available by use as a valid species before 1961. Bezzi & Stein (1907) and Peck (1988) did not include Eumerus nivipes in the catalog of Palaearctic Diptera; Kertész (1910: 314) treated Eumerus nivipes as junior synonym of Eumerus argyropus Loew, 1848. Morge (1959b: 88) listed this nominal species among the Rondani types in the MZUB but, because a list or index of names cannot be used to determine validity, O’Hara et. al. (2011: 212) considered the name as unavailable, which we follow here.
description: Published as part of Sforzi, Alessandra & Sommaggio, Daniele, 2021, Catalog of the Diptera types described by Camillo Rondani, pp. 1-438 in Zootaxa 4989 (1) on page 277, DOI: 10.11646/zootaxa.4989.1.1, http://zenodo.org/record/4980621
2014 Taking America’s Pulse Survey, Designed by Students at Cornell
Creators: name: University, Cornell
name: Schuldt, Jonathon P.
name: Enns, Peter K.
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: Perception of news program credibility influenced by newscaster wardrobe (1); television more or less offensive since 2000 (1); lack of privacy for celebrities (1); type of TV shows watched (1); online revues of musician or venue (1); rap/hip-hop does/does not cause underage drinking (1); long-term brain injuries from tackle football (1); FIFA corruption vs. US government corruption (1); effect of social media on in-person relationships (1); cyberbullying vs. face-to-face bullying (1); engaging with corporations on social media (1); impact of mobile phone and/or laptop use on attention span (1); companies collecting personal data online (1); eating less meat (1); information most likely to cause you to combat climate change (1); support for policies to reduce climate change (12); recently contacted local elected officials (1); spending on local infrastructure (1); state-run health insurance exchange (2); local criminal activity (2); do police officers respect you (1); would you accept/not accept a middle/high school teaching position (1); choice of program cut at public school (1); students vs. government paying college tuition (1); college/university rankings (1); supporting a candidate raised in your area with place of birth not specified (1); supporting a candidate raised in your area but born in a developing nation (1); government spending on welfare benefits (1); felons should/should not have right to vote (1); favor/oppose harsher prison sentences for convicted felons (2); would someone of your own race/ethnicity better represent you in Congress (1); Barack Obama vs. Mitt Romney in 2012 presidential election (1); would you have voted for Obama if he ran with same policies but as Republican (1); would you have voted for Romney if he ran with same policies but as Democrat (1); Democrats or Republicans have women’s best interests at heart (1); attitude toward China (1); violation of personal privacy rights justified (1); National Security Agency (NSA) ever listened to your phone calls (1); reduce government surveillance (1); middle class income level (2); federal minimum wage (1); tax levels for the wealthy (1); children will be better off/not better off than parents (1); legalization of marijuana (1); economic inequality in US (1); happy/unhappy with life (1); Christian church attendance (1); religious displays on government property (1); flossing teeth (2); government programs to fight obesity (1); physician-assisted suicide (2); stay in current state/move to different state if you had the choice (1); social media use (1); internet use (1).
Additional file 1 of Feasibility, safety, and resource utilisation of active mobilisation of patients on extracorporeal life support: a prospective observational study
Creators: name: Braune, Stephan
name: Bojes, Patrick
name: Mecklenburg, Anne
name: Angriman, Federico
name: Soeffker, Gerold
name: Warnke, Katja
name: Westermann, Dirk
name: Blankenberg, Stefan
name: Kubik, Mathias
name: Reichenspurner, Hermann
name: Kluge, Stefan
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Science Policy

description: Additional file 1: Table 1. Respiratory, haemodynamic, and renal variables within 6 hours before initiation of ECLS according to level of mobilisation.
Probing Our Heliospheric History I: High-Resolution Observations of Na I and Ca II Along the Solar Historical Trajectory
Creators: name: Wyman, Katherine
name: Redfield, Seth
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Over the course of its motion through the Galaxy, our solar system has encountered many interstellar environments of varying characteristics. Interstellar medium (ISM) density variations spanning seven orders of magnitude are commonly seen throughout the general Galactic environment, and a sufficiently dense cloud within this range has the potential to dramatically alter the structure of the heliosphere. We present observations of the ISM environments the Sun has most recently encountered based on high-resolution optical spectra toward nearby stars in the direction of the historical solar trajectory. The data were obtained with the highest-resolution spectrographs available, including the Tull Spectrograph on the Harlan J. Smith Telescope at McDonald Observatory and the Ultra-High-Resolution Facility on the Anglo-Australian Telescope at the Anglo-Australian Observatory. Observations were made of interstellar Na I and Ca II doublet absorption toward 43 bright stars within about 500 pc. No absorption is seen out to a distance of 120 pc (consistent with the outer boundary of the Local Bubble), but a complex collection of absorbers is seen in stars beyond 120 pc. While common absorbers are consistently seen in most sight lines, significant spatial variation is also detected, even between closely spaced sight lines. This pervasive evidence of small-scale structure not only speaks to the complexity of the morphology or physical properties of the gas in the ISM, but also emphasizes that dramatic structural changes to the heliosphere are common and it is important to understand the implications of such changes, such as the modulation in the cosmic ray flux, on planets.
Pazopanib with 5‐FU and oxaliplatin as first line therapy in advanced gastric cancer: A randomized phase‐II study—The PaFLO trial. A study of the Arbeitsgemeinschaft Internistische Onkologie AIO‐STO‐0510
Creators: name: Högner, Anica
name: Al‐Batran, Salah‐Eddin
name: Siveke, Jens T.
name: Lorenz, Mario
name: Bartels, Prisca
name: Breithaupt, Kirstin
name: Malfertheiner, Peter
name: Homann, Nils
name: Stein, Alexander
name: Gläser, Dietrich
name: Tamm, Ingo
name: Hinke, Axel
name: Vogel, Arndt
name: Thuss‐Patience, Peter
name: PaFLO Investigators
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: FLO
subject: gastric cancer
subject: GEJ cancer
subject: PaFLO
subject: pazopanib
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: VEGF inhibition in gastric cancer has a proven benefit in the second line setting. Pazopanib, an oral tyrosine kinase inhibitor, selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R resulting in inhibition of angiogenesis. This open-label randomized phase II trial (2:1) investigated the efficacy of combining pazopanib with FLO (5-fluorouracil, oxaliplatin) vs FLO alone (internal control arm) as first-line treatment in patients with advanced adenocarcinoma of the stomach and gastroesophageal junction (GEJ). Eighty-seven patients were randomized and 78 patients were eligible and evaluable (PaFLO arm 51 patients, FLO arm 27 patients). The PFS rate at 6 months (primary endpoint) was 34% in the PaFLO arm vs 30% in the FLO arm. Comparing PaFLO with FLO median PFS was 4.66 months (95% confidence interval [CI] 2.87-6.46) vs 4.47 months (95% CI 1.79-7.14) (95% CI, hazard ratio [HR] 0.96 (0.60-1.55), P = .882 [exploratory]); median OS was 10.19 months (95% CI 5.46-14.92) vs 7.33 months (95% CI 4.93-9.73), (95% CI HR 1.01 [0.62-1.65], P = .953, exploratory), disease control rate was 72% vs 59%. PaFLO was well tolerable, toxicities were slightly higher in the PaFLO arm. Major adverse events were loss of appetite, nausea, fatigue, diarrhea, neutropenia and thrombocytopenia. Adding pazopanib to chemotherapy shows signs of efficacy but no major improvement in this randomized phase 2 trial. The PFS at 6 months in both arms was lower than expected from the literature. Biomarkers identifying subgroups who benefit and novel combinations are needed. ClinicalTrials.gov: NCT01503372.
Cardiac cysteine and glycine rich protein 3 (CSRP3) induces renal myogenesis leading to CKD
Creators: name: Funahashi, Yoshio
name: Hebert, Jessica
name: Munhall, Adam
name: Groat, Tahnee
name: Hutchens, Michael
Publisher: name: Oregon Health and Science University
Year: 2023
Subjects: subject: Pathology
subject: Molecular Biology
subject: Cell Biology
subject: Hypertension
subject: Cardio-Renal Syndrome
subject: Acute Kidney Injury
subject: Fibrosis
subject: Cardiorenal Syndrome, Type 1
subject: Chronic Kidney Disease

description: Acute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are unclear. Cardiac LIM protein (CSRP3) is a cardiomyocyte differentiation factor which is released into plasma after cardiac arrest. We hypothesized that CSRP3 induces myogenesis in the renal proximal tubule, inducing CKD.
Direct Evidence of a Slow‐Slip Transient Modulating the Spatiotemporal and Frequency‐Magnitude Earthquake Distribution: Insights From the Armutlu Peninsula, Northwestern Turkey
Creators: name: Bocchini, G. M.
name: Martínez‐Garzón, P.
name: Verdecchia, A.
name: Harrington, R. M.
name: Bohnhoff, Marco
name: Turkmen, T.
name: Nurlu, M.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: microseismicity
subject: enhanced catalog
subject: near‐fault monitoring
subject: seismic‐aseismic deformation
subject: slow‐slip transient
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::550 Geowissenschaften

description: Earthquakes and slow‐slip events interact, however, detailed studies investigating their interplay are still limited. We generate the highest resolution microseismicity catalog to date for the northern Armutlu Peninsula in a ∼1‐year period to perform a detailed seismicity distribution analysis and correlate the results with a local, geodetically observed slow‐slip transient within the same period. Seismicity shows a transition of cluster‐type behavior from swarm‐like to burst‐like, accompanied by an increasing relative proportion of clustered (non‐Poissonian) relative to background (Poissonian) seismicity and gradually decreasing b‐value as the geodetically observed slow‐slip transient ends. The observed slow‐slip transient decay correlates with gradually increasing effective‐stress‐drop values. The observed correlation between the b‐value and geodetic transient highlights the influence of aseismic deformation on seismic deformation and the impact of slow‐slip transients on local seismic hazard.
Additional file 2 of Feasibility, safety, and resource utilisation of active mobilisation of patients on extracorporeal life support: a prospective observational study
Creators: name: Braune, Stephan
name: Bojes, Patrick
name: Mecklenburg, Anne
name: Angriman, Federico
name: Soeffker, Gerold
name: Warnke, Katja
name: Westermann, Dirk
name: Blankenberg, Stefan
name: Kubik, Mathias
name: Reichenspurner, Hermann
name: Kluge, Stefan
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Science Policy

description: Additional file 2: Table 2. Variation of haemodynamic state, oxygenation, and ECLS blood flow over the course of each active mobilisation unit IMS ≥ 3.
Waist dependence of a Gaussian beam on the propagation distance, and calculation of the diffraction patterns of a slit in the far and near field
Creators: name: Sabogal, Miguel
Publisher: name: Zenodo
Year: 2018

description: It was carried out the study, calculation and analysis of the drifraccion patterns that occur when a plane wave go through a slit, both near and far field using the FFT in MATLAB. verifying the results predicted by Fresnel and Fraunhofer diffraction theory. Similarly, using the FFT it was corroborated the waist dependence of a Gaussian beam to the distance propagation. With discrepancies lower than 1 % with respect to the predicted by the theory of Gaussian beams.
description: College project
Anatomy of perpendicular magnetic anisotropy in Fe/MgO magnetic tunnel junctions: First principles insight
Creators: name: Hallal, A.
name: Yang, H. X.
name: Dieny, B.
name: Chshiev, M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Using first-principles calculations, we elucidate microscopic mechanisms of perpendicular magnetic anisotropy (PMA)in Fe/MgO magnetic tunnel junctions through evaluation of orbital and layer resolved contributions into the total anisotropy value. It is demonstrated that the origin of the large PMA values is far beyond simply considering the hybridization between Fe-3d$ and O-2p orbitals at the interface between the metal and the insulator. On-site projected analysis show that the anisotropy energy is not localized at the interface but it rather propagates into the bulk showing an attenuating oscillatory behavior which depends on orbital character of contributing states and interfacial conditions. Furthermore, it is found in most situations that states with $d_{yz(xz)}$ and $d_{z^2}$ character tend always to maintain the PMA while those with $d_{xy}$ and $d_{x^2-y^2}$ character tend to favor the in-plane anisotropy. It is also found that while MgO thickness has no influence on PMA, the calculated perpendicular magnetic anisotropy oscillates as a function of Fe thickness with a period of 2ML and reaches a maximum value of 3.6 mJ/m$^2$.
description: 5 pages, 5 figures
One‐Pot Covalent Functionalization of 2D Black Phosphorus by Anionic Ring Opening Polymerization
Creators: name: Bawadkji, Obida
name: Cherri, Mariam
name: Schäfer, Andreas
name: Herziger, Svenja
name: Nickl, Philip
name: Achazi, Katharina
name: Donskyi, Ievgen S.
name: Adeli, Mohsen
name: Haag, Rainer
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: 2D nanomaterials
subject: amphiphilicity
subject: black phosphorus
subject: hyperbranched polyglycerol
subject: water dispersibility
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: In this work, a one‐pot approach for the covalent functionalization of few‐layer black phosphorus (BP) by anionic ring opening polymerization of glycidol to obtain multifunctional BP‐polyglycerol (BP‐PG) with high amphiphilicity for near‐infrared‐responsive drug delivery and biocompatibility is reported. Straightforward synthesis in combination with exceptional biological and physicochemical properties designates functionalized BP‐PG as a promising candidate for a broad range of biomedical applications.
Insights on the Lewis Superacid Al(OTeF5)3: Solvent Adducts, Characterization and Properties
Creators: name: Hoffmann, Kurt F.
name: Wiesner, Anja
name: Steinhauer, Simon
name: Riedel, Sebastian
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: aluminum
subject: coordination chemistry
subject: fluorine chemistry
subject: Lewis superacids
subject: pentafluoroorthotellurate
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Preparation and characterization of the dimeric Lewis superacid [Al(OTeF5)3]2 and various solvent adducts is presented. The latter range from thermally stable adducts to highly reactive, weakly bound species. DFT calculations on the ligand affinity of these Lewis acids were performed in order to rank their remaining Lewis acidity. An experimental proof of the Lewis acidity is provided by the reaction of solvent‐adducts of Al(OTeF5)3 with [PPh4][SbF6] and OPEt3, respectively. Furthermore, their reactivity towards chloride and pentafluoroorthotellurate salts as well as (CH3)3SiCl and (CH3)3SiF is shown. This includes the formation of the dianion [Al(OTeF5)5]2−.
Eumerus parvulus Rondani 1850
Creators: name: Sforzi, Alessandra
name: Sommaggio, Daniele
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Eumerus
Eumerus parvulus

description: [Eumerus parvulus] Rondani, 1850a: 128.
REMARKS: name that Rondani (1850a: 128) proposed as a synonym of Eumerus delicatae Rondani, 1850 and was not made available by use as a valid species before 1961 (Loew 1855, Verrall 1901, Bezzi & Stein 1907, Kertész 1910, Sack 1932). Peck (1988) did not list this name. O’Hara et. al. (2011: 212) incorrectly considered the name as available.
description: Published as part of Sforzi, Alessandra & Sommaggio, Daniele, 2021, Catalog of the Diptera types described by Camillo Rondani, pp. 1-438 in Zootaxa 4989 (1) on page 277, DOI: 10.11646/zootaxa.4989.1.1, http://zenodo.org/record/4980621
Sex‐specific genetic factors affect the risk of early‐onset periodontitis in Europeans
Creators: name: Freitag‐Wolf, Sandra
name: Munz, Matthias
name: Junge, Olaf
name: Graetz, Christian
name: Jockel‐Schneider, Yvonne
name: Staufenbiel, Ingmar
name: Bruckmann, Corinna
name: Lieb, Wolfgang
name: Franke, Andre
name: Loos, Bruno G.
name: Jepsen, Søren
name: Dommisch, Henrik
name: Schaefer, Arne S.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: alveolar bone loss
subject: gene x sex interaction
subject: genetic risk
subject: heritability
subject: inflammation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Aims: Various studies have reported that young European women are more likely to develop early-onset periodontitis compared to men. A potential explanation for the observed variations in sex and age of disease onset is the natural genetic variation within the autosomal genomes. We hypothesized that genotype-by-sex (G × S) interactions contribute to the increased prevalence and severity. Materials and methods: Using the case-only design, we tested for differences in genetic effects between men and women in 896 North-West European early-onset cases, using imputed genotypes from the OmniExpress genotyping array. Population-representative 6823 controls were used to verify that the interacting variables G and S were uncorrelated in the general population. Results: In total, 20 loci indicated G × S associations (P < 0.0005), 3 of which were previously suggested as risk genes for periodontitis (ABLIM2, CDH13, and NELL1). We also found independent G × S interactions of the related gene paralogs MACROD1/FLRT1 (chr11) and MACROD2/FLRT3 (chr20). G × S-associated SNPs at CPEB4, CDH13, MACROD1, and MECOM were genome-wide-associated with heel bone mineral density (CPEB4, MECOM), waist-to-hip ratio (CPEB4, MACROD1), and blood pressure (CPEB4, CDH13). Conclusions: Our results indicate that natural genetic variation affects the different heritability of periodontitis among sexes and suggest genes that contribute to inter-sex phenotypic variation in early-onset periodontitis.
Additional file 3 of Feasibility, safety, and resource utilisation of active mobilisation of patients on extracorporeal life support: a prospective observational study
Creators: name: Braune, Stephan
name: Bojes, Patrick
name: Mecklenburg, Anne
name: Angriman, Federico
name: Soeffker, Gerold
name: Warnke, Katja
name: Westermann, Dirk
name: Blankenberg, Stefan
name: Kubik, Mathias
name: Reichenspurner, Hermann
name: Kluge, Stefan
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Science Policy

description: Additional file 3: Table 3. Duration of ECLS treatments according to type of ECLS and ICU-mortality.
Bericht des volkswirthschaftlichen Ausschusses über den Entwurf des deutschen Heimathsgesetzes; [1848]
Creators: name: Hildebrand, Bruno
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2018

description: Beilage I zum Protokoll der 127. öffentl. Sitzung vom 2. Dezember 1848
Efficacy of tooth splinting and occlusal adjustment in patients with periodontitis exhibiting masticatory dysfunction: A systematic review
Creators: name: Dommisch, Henrik
name: Walter, Clemens
name: Difloe‐Geisert, Julia C.
name: Gintaute, Aiste
name: Jepsen, Søren
name: Zitzmann, Nicola U.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: occlusal adjustment
subject: occlusal equilibration
subject: periodontal splinting
subject: periodontitis
subject: secondary occlusal trauma
subject: tooth survival
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objective: To evaluate the efficacy of tooth splinting (TS) and occlusal adjustment (OA) compared to no TS or OA in patients with periodontitis exhibiting masticatory dysfunction. Material: The primary outcome criterion was tooth loss (TL), and the secondary outcome parameters were change in probing pocket depth (PPD), change in clinical attachment level (CAL), tooth mobility (TM), and patient-reported outcome measures (PROMs). Literature search was performed on three electronic databases (from 01/1965 to 04/2021) and focused on clinical studies with at least 12 months follow-up. Results: From a total of 1515 publications, 51 articles were identified for full-text reading, of which 2 retrospective case series on TS with low risk of bias and 1 randomized and 2 prospective studies on OA with unclear risk of bias were included. For TS, synthesis of data showed that in 72 patients, 26 out of 311 teeth (weighted mean incidence of TL 8.4%) and 156 out of 1541 teeth with no TS (weighted mean incidence of TL 10.1%) were lost over 2 years following non-surgical periodontal therapy. The randomized controlled clinical trial (RCT) indicated CAL gain for teeth with OA compared to no OA. For the effect of OA on TL, PPD, and TM, heterogeneous data were retrieved from the included studies. Conclusions: Within the limitations of this review and based on a low level of evidence, it is concluded that TS does not improve survival of mobile teeth in patients with advanced periodontitis. OA on teeth with mobility and/or premature contacts may lead to improved CAL, while the effect of OA on the remaining periodontal parameters remains unclear.
A 33 year constancy of the X-ray coronae of AR Lac and eclipse diagnosis of scale height
Creators: name: Drake, Jeremy J.
name: Ratzlaff, Peter
name: Kashyap, Vinay
name: Huenemoerder, David P.
name: Wargelin, Bradford J.
name: Pease, Deron O.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Extensive X-ray and extreme ultraviolet (EUV) photometric observations of the eclipsing RS CVn system AR Lac were obtained over the years 1997 to 2013 with the Chandra X-ray Observatory Extreme Ultraviolet Explorer. During primary eclipse, HRC count rates decrease by ~40%. A similar minimum is seen during one primary eclipse observed by EUVE but not in others owing to intrinsic source variability. Little evidence for secondary eclipses is present in either the X-ray or EUV data, reminiscent of earlier X-ray and EUV observations. Primary eclipses allow us to estimate the extent of a spherically symmetric corona on the primary G star of about 1.3Rsun, or 0.86Rstar, and indicate the G star is likely brighter than the K component by a factor of 2-5. Brightness changes not attributable to eclipses appear to be dominated by stochastic variability and are generally non-repeating. X-ray and EUV light curves cannot therefore be reliably used to reconstruct the spatial distribution of emission assuming only eclipses and rotational modulation are at work. Moderate flaring is observed, where count rates increase by up to a factor of three above quiescence. Combined with older ASCA, Einstein, EXOSAT, ROSAT and Beppo-SAX observations, the data show that the level of quiescent coronal emission at X-ray wavelengths has remained remarkably constant over 33 years, with no sign of variation due to magnetic cycles. Variations in base level X-ray emission seen by Chandra over 13 years are only ~10%, while variations back to pioneering Einstein observations in 1980 amount to a maximum of 45% and more typically about 15%.
description: To appear in the Astrophysical Journal
Additional file 1 of Baseline liver function tests and full blood count indices and their association with progression of chronic kidney disease and renal outcomes in Aboriginal and Torres Strait Islander people: the eGFR follow- up study
Creators: name: Majoni, Sandawana William
name: Barzi, Federica
name: Hoy, Wendy
name: MacIsaac, Richard J.
name: Cass, Alan
name: Maple-Brown, Louise
name: Jaquelyne T. Hughes
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Science Policy
subject: Computational Biology

description: Additional file 1: Table S1. Association of quintiles of baseline concentrations of measures of LFTS and annual decline in eGFR adjusted for age, gender, UACR, diabetes and CRP, total cholesterol, triglycerides, BMI, WHR, Alcohol consumption. Table S2. Association of quintiles of levels of FBC indices and annual decline in eGFR adjusted for age, gender, UACR, diabetes and CRP, total cholesterol, triglycerides, BMI, WHR, Alcohol consumption.
Additional file 1 of Chitosan modifies glycemic levels in people with metabolic syndrome and related disorders: meta-analysis with trial sequential analysis
Creators: name: Wenfang Guo
name: Letai Yi
name: Baochang Zhou
name: Li, Minhui
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy

description: Additional file 1. Search Strategy.
From Cues to Signals: Evolution of Interspecific Communication Via Aposematism and Mimicry in a Predator-Prey System
Creators: name: Lehmann, Kenna D. S.
name: Goldman, Brian W.
name: Dworkin, Ian
name: Bryson, David M.
name: Wagner, Aaron P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: Current evolutionary theory suggests that many natural signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the unpalatable species, exploiting the signaling system for its own protection. We investigated the evolutionary development of predator cue utilization and prey signaling in a digital predator-prey system in which mimicking prey could evolve to alter their appearance to resemble poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication systems and signals incorporating information about the environment.