cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Characterization of modern reefs using the Atlantic and Gulf Rapid Reef Assessment (AGRRA) protocol and digitized aerial photographs, Tobago Cays Marine Park, St. Vincent and the Grenadines.
Creators: name: Deschamps, Alice.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Geology.

description: A digital thematic map of the shallow marine habitats surrounding the Tobago Cays and the Horseshoe Reef was created using a low-cost remote sensing methodology. Colour aerial photographs were selected because of their high spatial resolution and availability. The aerial photographs were scanned, georeferenced, rectified (ground control points and a second order polynomial) and mosaicked to cover the entire study arm. Benthic classes were derived and described objectively using agglomerative hierarchical classification of field data. Supervised classification of the Tobago Cays was obtained using this field derived classification. The final thematic map comprises 8 classes (mixed live coral community, dead coral substratum with mixed algae, seagrass dominated, macro algae dominated, sand dominated, rubble dominated, deep water and beach sands) with an overall accuracy of 87% and a Kappa and Tau coefficients of 85%. Producer and user accuracies of individual classes range between 53% and 100%. (Abstract shortened by UMI.)
The potential of CD16 on plasma-derived exosomes as a liquid biomarker in head and neck cancer
Creators: name: Hofmann, Linda
name: Ludwig, Sonja
name: Schuler, Patrick J.
name: Hoffmann, Thomas K.
name: Brunner, Cornelia
name: Theodoraki, Marie-Nicole
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: HNSCC
subject: liquid biomarker
subject: CD16
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Exosomes
subject: Squamous Cell Carcinoma of Head and Neck
subject: Receptors, IgG
subject: Biomarker

description: Head and neck squamous cell carcinomas (HNSCC) are highly immune suppressive and aggressive malignancies. As part of the tumor microenvironment, exosomes contribute to this immune suppression. The Fc receptor CD16 is widely expressed on monocytes, neutrophils, and natural killer (NK) cells and is involved in antibody-dependent cell-mediated cytotoxicity (ADCC). Here, surface levels of CD16 on total exosomes and tumor-derived exosomes (TEX) from plasma of HNSCC patients were analyzed regarding their potential as liquid biomarkers for disease stage. Exosomes were isolated from plasma using mini size exclusion chromatography. TEX were enriched by immune affinity capture with CD44v3 antibodies. On-bead flow cytometry was used to measure CD16 levels on total exosomes and TEX. The results were correlated with clinicopathological parameters. Total exosomes from HNSCC patients had significantly higher CD16 levels compared to TEX. Further, CD16 surface levels of total exosomes, but not TEX, correlated with clinicopathological parameters. Patients with advanced tumor stages T3/4 and Union for International Cancer Control (UICC) stages III/IV had significantly higher CD16 levels on total exosomes compared to patients with early tumor stages T1/2 and UICC stages I/II, respectively. Overall, CD16 positive exosomes have the potential as liquid biomarkers for HNSCC tumor stage and aggressiveness.
Effect of Alkaline Pretreatment on Anaerobic Digestion of Organic Fraction of Municipal Solid Waste
Creators: name: Alqaralleh, Rania Mona
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Solubilization
Sodium hydroxide
Potassium hydroxide
Alkaline pretreatment
Anaerobic biodegradability

description: The rapid accumulation of municipal solid waste is a significant environmental concern in our rapidly growing world. Due to its low cost, high energy recovery and limited environmental impact anaerobic digestion (AD) is a promising solution for stabilizing the organic fraction of municipal solid waste (OFMSW). Hydrolysis is often the rate-limiting step during AD of wastes with high solid content; this step can be accelerated by pretreatment of waste prior to AD. This thesis presents the results of alkaline pretreatment of OFMSW using NaOH and KOH. Four different pH levels 10, 11, 12 and 13 at two temperatures 23±1°C and 80±1°C were examined to study the effects of the pretreatment on (i) enhancing the solubility of the organic fraction of the waste, and (ii) enhancing the AD process and the biogas production. The effects on solubility were investigated by measuring changes in the soluble COD (SCOD) concentrations of pretreated wastes and the enhanced AD was investigated by measuring volatile solids (VS) destruction, total COD (TCOD) and SCOD removal in addition to biogas and methane production using biochemical methane potential (BMP) assay and semi-continuous laboratory reactor experiments. Pretreatment at pH 13 at 80±1°C demonstrated the maximum solubility for both NaOH and KOH pretreated samples; however the BMP analysis demonstrated that pretreatment at pH 12 at 23±1°C showed the greatest biogas yield relative to the removed VS for both chemicals. Thus pretreatment at pH 12 at 23±1°C using NaOH and KOH were examined using semi-continuous reactors at three different HRTs: 10, 15 and 20 days. Pretreatment demonstrated a significant improvement in the AD performance at SRTs of 10 and 15 days.
Additional file 3 of Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model
Creators: name: Crépey, Pascal
name: Boiron, Louis
name: Araujo, Rafael Rodrigo
name: Lopez, Juan Guillermo
name: Petitjean, Audrey
name: Expedito José De Albuquerque Luna
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3 : Table S1. Proportions of influenza A/H1N1, A/H3N2, B Victoria, B Yamagata circulating for the period 2010–2017 in Brazil.
Abattoir waste use in livestock diets: Uganda’s current situation
Creators: name: Mwesigwa, R.
name: Migwi, P.K.
name: King’ori, A.M.
name: Onjoro, P.A.
name: Mwesigwa, R.
name: Migwi, P.K.
name: King’ori, A.M.
name: Onjoro, P.A.
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Regulation awareness
subject: Livestock slaughtered
subject: Slaughter waste contaminants

description: In this study, we investigated the various ways slaughter wastes are utilized, problems encountered in order to give insights in future prospects of abattoir wastes as livestock feeds. A total of 100 abattoir workers were interviewed through semi-structured questionnaires covering Kampala, Wakiso and Mukono districts in Uganda. Results revealed that majority of abattoir work force were middle-aged adults between 30-45 years contributing 37% of total workers. There was a significant association between abattoir workers responses in relation to the proportion of livestock slaughtered (Chi square 147.55; df =2; p<0.0001) in the abattoirs. With reference to cattle, 1.06 and 1.01 more sheep and goats were slaughtered respectively in the dry season in comparison to the wet season. Blood was mostly disposed as animal feed ingredient (blood meal) by 40% of the respondents while rumen contents were mostly sold as manure by 59% of the respondents. Only 16% of the respondents processed rumen contents for livestock feeding. 92.3% of bones were sold for dog feeding while 7.7% of bones were processed for livestock feed ingredients. Polythene bags were reported the biggest contaminants found in slaughter wastes. Stench from slaughter wastes contents was the biggest problem encountered with handling of waste products by (62%) of the respondents. The handling of abattoir wastes was still rudimental at most abattoirs as envisaged by lack of proper handling facilities at the abattoirs. There is need for regular enforcements to ensure proper abattoir waste disposal mechanisms for enhanced livestock use.
Additional file 10 of Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model
Creators: name: Crépey, Pascal
name: Boiron, Louis
name: Araujo, Rafael Rodrigo
name: Lopez, Juan Guillermo
name: Petitjean, Audrey
name: Expedito José De Albuquerque Luna
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 10 : Table S8. Single year impact of the switch from TIV to QIV in the pediatric population. In this analysis the model is run on each influenza season separately. The population in the QIV scenario and the basecase scenario starts each year with the same immune status, hence there is no additional build-up of naturally acquired immunity in the population vaccinated with TIV as it happens when simulations are performed over multiple years.
The software engineering of agent-based intelligent adaptive systems
Creators: name: Sterling, Leon
name: Juan, Thomas
Publisher: name: Swinburne
Year: 2024

description: Future software systems will be intelligent and adaptive. They will have the ability to seamlessly integrate with smart applications that have not been explicitly designed to work together. Traditional software engineering approaches offer limited support for the development of intelligent systems. To handle the tremendous complexity and the new engineering challenges presented by intelligence, adaptiveness and seamless integration, developers need higher-level development constructs. Agent concepts are natural to describe intelligent adaptive systems. Agent-based technologies have been incorporating software engineering practices, and have matured to offer useful insights and concrete practices to mainstream software engineers. This tutorial presents the state of the art in agent development from a software engineering perspective, focusing on practices that are applicable today. We will walk the audience through analysis, design and verification of a portion of a real-world problem: a Smart Home Network. We show how agent concepts more naturally match the engineering challenges of such systems like trust between adaptive components. The audience will have hands-on experience with analyzing and designing parts of the Smart Home Network and learn how to incorporate agent technologies into their current projects.
Towards Fault Reactiveness in Wireless Sensor Networks with Mobile Carrier Robots
Creators: name: Falcon Martinez, Rafael Jesus
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: wireless sensor networks
mobile robots
computational intelligence
distributed computing
nature-inspired metaheuristic optimization
risk management framework

description: Wireless sensor networks (WSN) increasingly permeate modern societies nowadays. But in spite of their plethora of successful applications, WSN are often unable to surmount many operational challenges that unexpectedly arise during their lifetime. Fortunately, robotic agents can now assist a WSN in various ways. This thesis illustrates how mobile robots which are able to carry a limited number of sensors can help the network react to sensor faults, either during or after its deployment in the monitoring region. Two scenarios are envisioned. In the first one, carrier robots surround a point of interest with multiple sensor layers (focused coverage formation). We put forward the first known algorithm of its kind in literature. It is energy-efficient, fault-reactive and aware of the bounded robot cargo capacity. The second one is that of replacing damaged sensing units with spare, functional ones (coverage repair), which gives rise to the formulation of two novel combinatorial optimization problems. Three nature-inspired metaheuristic approaches that run at a centralized location are proposed. They are able to find good-quality solutions in a short time. Two frameworks for the identification of the damaged nodes are considered. The first one leans upon diagnosable systems, i.e. existing distributed detection models in which individual units perform tests upon each other. Two swarm intelligence algorithms are designed to quickly and reliably spot faulty sensors in this context. The second one is an evolving risk management framework for WSNs that is entirely formulated in this thesis.
Ratios of charged antiparticles to particles near midrapidity in Au + Au collisions at square root SNN = 200 GeV
Creators: name: Back, B. B.
name: Baker, M. D.
name: Barton, D. S.
name: Betts, R. R.
name: Ballintijn, M.
name: Bickley, A. A.
name: Bindel, R.
name: Budzanowski, A.
name: Busza, W.
name: Carroll, A.
name: Decowski, M. P.
name: Garcia, E.
name: George, N.
name: Gulbrandsen, K.
name: Gushue, S.
name: Halliwell, C.
name: Hamblen, J.
name: Heintzelman, G. A.
name: Henderson, C.
name: Hofman, D. J.
name: Hollis, R. S.
name: Holynski, R.
name: Holzman, B.
name: Iordanova, A.
name: Johnson, E.
name: Kane, J. L.
name: Katzy, J.
name: Khan, N.
name: Kucewicz, W.
name: Kulinich, P.
name: Kuo, C. M.
name: Lin, W. T.
name: Manly, S.
name: McLeod, D.
name: Michalowski, J.
name: Mignerey, A. C.
name: Nouicer, R.
name: Olszewski, A.
name: Pak, R.
name: Park, I. C.
name: Pernegger, H.
name: Reed, C.
name: Remsberg, L. P.
name: Reuter, M.
name: Roland, C.
name: Roland, G.
name: Rosenberg, L.
name: Sagerer, J.
name: Sarin, P.
name: Sawicki, P.
name: Skulski, W.
name: Steadman, S. G.
name: Steinberg, P.
name: Stephans, G. S. F.
name: Stodulski, M.
name: Sukhanov, A.
name: Tang, J.-L.
name: Teng, R.
name: Trzupek, A.
name: Vale, C.
name: van Nieuwenhuizen, G. J.
name: Verdier, R.
name: Wadsworth, B.
name: Wolfs, F. L. H.
name: Wosiek, B.
name: Wozniak, K.
name: Wuosmaa, A. H.
name: Wyslouch, B.
Publisher: name: Swinburne
Year: 2024

description: The ratios of charged antiparticles to particles have been obtained for pions, kaons, and protons near midrapidity in central Au+Au collisions at sqrt[sNN]=200 GeV. Ratios of 〈π-〉/〈π+〉=1.025±0.006(stat.)±0.018(syst.), 〈K-〉/〈K+〉=0.95±0.03(stat.)±0.03(syst.), and 〈p̅ 〉/〈p〉=0.73±0.02(stat.)±0.03(syst.) have been observed. The 〈K-〉/〈K+〉 and 〈p̅ 〉/〈p〉 ratios are consistent with a baryochemical potential μB of 27 MeV, roughly a factor of 2 smaller than in sqrt[sNN]=130 GeV collisions. The data are compared to results from lower energies and model calculations. Our accurate measurements of the particle ratios impose stringent constraints on current and future models dealing with baryon production and transport.
La reconstruction : analyse critique et portée de la philosophie morale de Jean-Marc Ferry pour l'éthique sociale théologique.
Creators: name: Jobin, Guy.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Philosophy.

description: Cette thèse est un essai de réception critique, d'un point de vue théologique, de trois versions contemporaines du procéduralisme: celle de John Rawls, de Jürgen Habermas, mais surtout celle de Jean-Marc Ferry. Si d'un côté, l'éthique sociale théologique chrétienne a fait un large accueil aux thèses communautariennes/contextualistes venant de la philosophie morale et politique, d'un autre côté, le procéduralisme, tant dans la version de John Rawls que celle de Jürgen Habermas, a été reçu beaucoup plus critiquement en raison notamment du rôle réduit attribué aux ressources normatives de la religion dans l'élaboration et la validation des normes communes de l'action. Pourtant, compte tenu des caractères de démocratisation, de sécularisation et de pluralisation des sociétés occidentales, il nous semble que le procéduralisme offre un modèle plus apte pour honorer, à la fois, la prétention à la validité des ressources normatives religieuses et les caractères fondamentaux des sociétés en question. Une analyse critique des procéduralismes rawlsien et habermassien sert d'entrée en matière à notre étude. Ces approches ont comme problème principal de reléguer en touche les ressources normatives des traditions religieuses. Chez Rawls, que ce soit dans la position originelle ou dans le consensus par recoupement, il y a limitation de l'apport des traditions religieuses dans à un rôle d'arrière-plan dans l'élaboration des normes communes. Les traditions religieuses ne peuvent espérer mieux que de jouer un rôle de caution de normes--en l'occurrence, les principes de justice--communes par ailleurs déjà légitimées par la procédure. Reste le procéduralisme de Jean-Marc Ferry qui se veut plus sensible au rapport entre raison et religion que l'éthique habermassienne et qui, potentiellement, intégrerait les ressources contextuelles de sens--dont les ressources religieuses--, contra Rawls. Faire la genèse de la notion de reconstruction nécessite d'en retracer la généalogie. Ferry étant un commentateur de Habermas, c'est en repérant une faille dans la théorie des activités rationnelles de Habermas que Ferry est amené à se démarquer du philosophe allemand. Si le geste généalogique met en relief la filiation critique de Ferry par rapport à Habermas, le geste systématique accentue le caractère d' Aufhebung de la reconstruction par rapport à l'argumentation habermassienne. (Abstract shortened by UMI.)
CCN2 Mediates S1P-Induced Upregulation of COX2 Expression in Human Granulosa-Lutein Cells
Creators: name: Hu, Liao-Liao
name: Chang, Hsun-Ming
name: Yi, Yuyin
name: Liu, Yingtao
name: Taylor, Elizabeth L.
name: Zheng, Li-Ping
name: Leung, P. C. K.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: CCN1 and CCN2 are members of the CCN family and play essential roles in the regulation of multiple female reproductive functions, including ovulation. Cyclooxygenase-2 (COX2) is a critical mediator of ovulation and can be induced by sphingosine-1-phosphate (S1P) through the S1P₁/₃-mediated Yes-associated protein (YAP) signaling. However, it is unclear whether CCN1 or CCN2 can mediate S1P-induced upregulation of COX2 expression and increase in prostaglandin E2 (PGE2) production in human granulosa-lutein (hGL) cells. In the present study, we investigated the effects of S1P on the expressions of CCN1 and CCN2 in hGL cells. Additionally, we used a dual inhibition approach (siRNA-mediated silencing and small molecular inhibitors) to investigate the molecular mechanisms of S1P effects. Our results showed that S1P treatment significantly upregulated the expression of CCN1 and CCN2 in a concentration-dependent manner in hGL cells. Additionally, inhibition or silencing of S1P₁, but not S1P₃, completely abolished the S1P-induced upregulation of CCN2 expression. Furthermore, we demonstrated that S1P-induced nuclear translocation of YAP and inhibition or silencing of YAP completely abolished the S1P-induced upregulation of CCN1 and CCN2 expression. Notably, silencing of CCN2, but not CCN1, completely reversed the S1P-induced upregulation of COX2 expression and the increase in PGE2 production. Thus, CCN2 mediates the S1P-induced upregulation of COX2 expression through the S1P1-mediated signaling pathway in hGL cells. Our findings expand our understanding of the molecular mechanism underlying the S1P-mediated cellular activities in the human ovary.
Supplementary document for Fifth-order intrinsic aberration calculation method for soft X-ray and vacuum ultraviolet optical system - 5151780.pdf
Creators: name: Cao, Yiqing
name: Shen, Zhijuan
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: This supplemental document gives the relationship between the wave aberration coefficient expressions with aperture-ray coordinates on the reference exit wavefront and the ones on the optical surface.
Additional file 5 of Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model
Creators: name: Crépey, Pascal
name: Boiron, Louis
name: Araujo, Rafael Rodrigo
name: Lopez, Juan Guillermo
name: Petitjean, Audrey
name: Expedito José De Albuquerque Luna
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 5 : Table S3. Health outcomes probabilities.
Supplementary document for Fifth-order intrinsic aberration calculation method for soft X-ray and vacuum ultraviolet optical system - 5151780.pdf
Creators: name: Cao, Yiqing
name: Shen, Zhijuan
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: This supplemental document gives the relationship between the wave aberration coefficient expressions with aperture-ray coordinates on the reference exit wavefront and the ones on the optical surface.
Trastorno del estado del ánimo con síntomas maniacos, inducido por corticoides nasales
Creators: name: Liaño Arriola, Cristina
name: Barana, Jose
name: Usuna, Estefanía
name: Pérez Gil, Sara
name: Royuela Rico, Ángel
name: Bravo Barba, Eva
name: Ruiz Sanz, Francisco Carlos
Publisher: name: Zenodo
Year: 2024

description: INTRODUCCIÓN Y OBJETIVOS:Se presenta el caso de una mujer con antecedentes de Trastorno Bipolar inducido por corticoides con características maniacas. El objetivo es mostrar la asociación de este fármaco con trastornos neuropsiquiátricos, siendo este caso de especial interés por la aparición a dosis bajas y el antecedente de otro episodio.

DESCRIPCIÓN DEL CASO:Mujer de 49 años ingresada involuntariamente en UHB a través del servicio de Urgencias por episodios de agresividad y agitación. Cuadro de un mes de evolución de irritabilidad, disminución del sueño e ideas delirantes de perjuicio y autorreferenciales. Su marido relaciona el inicio del cuadro con la vuelta de un viaje de trabajo, cuando presentó un cuadro catarral, siendo tratada con un nebulizador nasal (con corticoide como principio activo).

EXPLORACIÓN Y PRUEBAS COMPLEMENTARIAS:-EPP: Consciente, desorientada parcialmente en tiempo, bien orientada en espacio y persona. Abordable. Moderadamente colaboradora. Discurso desorganizado, limitado a preguntas, respuestas tangenciales. Hipertímica. Disfórica e irritable. No ideación autolítica. Ideas delirantes de perjuicio y autorreferenciales. No auto ni heteroagresividad. Nula conciencia de enfermedad. Sueño disminuido. -TAC craneal: no hallazgos significativos. Sin alteraciones respecto al previo (2017).-Analítica: no hallazgos significativos

DIAGNÓSTICO DIFERENCIAL Y TRATAMIENTO:Se establece diagnóstico de Trastorno del estado del ánimo con síntomas maniacos.Como primer paso se retiran los corticoides intranasales.Se inicia tratamiento con Olanzapina 15 mg/24 horas y Valproato 500mg/12 horas, con mejoría del cuadro.

DISCUSIÓN Y CONCLUSIONES:Efectos neuropsiquiátricos son reconocidos efectos secundarios del uso de corticoides. A corto plazo, el más frecuente es la manía/hipomanía; mientras que un tratamiento a largo plazo se relaciona más con síntomas depresivos. Pueden ocurrir hasta en un 60% de los casos, observándose una relación dosis-respuesta. Sin embargo, dosis bajas (corticoide nasal) puede provocar esta afección.La recuperación completa ocurre en más del 90%, siendo un pequeño porcentaje recurrente o permanente.Además, el haber presentado un cuadro neuropsiquiátrico inducido por corticoides, se asocia con un aumento de la recurrencia. Se puede plantear contraindicación de los corticoides o, si es posible, profilaxis con un antipsicótico de segunda generación.
Additional file 9 of Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model
Creators: name: Crépey, Pascal
name: Boiron, Louis
name: Araujo, Rafael Rodrigo
name: Lopez, Juan Guillermo
name: Petitjean, Audrey
name: Expedito José De Albuquerque Luna
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 9 : Table S7. Public health and economic impact of the QIV strategy compared to TIV. Costs and ICER are given in 2017 US dollars.
Étude pré-post de santé mentale et de besoins d'aidants naturels primaires de patients en attente de pontages aortocoronariens.
Creators: name: Morin, Joanne L.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Health Sciences, Mental Health.

description: Il s'agit d'une étude ayant pour but d'examiner les besoins perçus et le niveau de détresse mentale d'aidants naturels primaires (ANP) de patients en attente de pontages aortocoronariens (PAC). Le devis de recherche consiste en un pré-post-test auprès d'un échantillon aléatoire de 19 ANP. L'Inventaire des Besoins des Familles (IBF) et le Brief Symptom Inventory (BSI) ont servi à mesurer respectivement les besoins et la détresse mentale auprès de la clientèle cible, les ANP, avant (T1 ) et suivant (T2 ) une session d'information. Les résultats révèlent qu'il existe une différence significative (p = 0,015) à la dimension besoins physiques entre les deux intervalles de temps visés. La corrélation entre les besoins et la santé mentale s'accroît avec le temps. L'âge est corrélée positivement (r = 0,51) avec l'indice de détresse mentale au T1 . Les ANP ayant une scolarité post-secondaire présentent un score plus élevé (p = 0,02) au nombre total de besoins comparativement aux autres.
Establishing Live-Cell Single-Molecule Localization Microscopy Imaging and Single-Particle Tracking in the Archaeon Haloferax volcanii
Creators: name: Turkowyd, Bartosz
name: Schreiber, Sandra
name: Wörtz, Julia
name: Segal, Ella Shtifman
name: Mevarech, Moshe
name: Duggin, Iain G.
name: Marchfelder, Anita
name: Endesfelder, Ulrike
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: single-molecule imaging and tracking
subject: advanced fluorescence microscopy
subject: archaeal cell imaging
subject: imaging technology in microbiology
subject: FtsZ1 division ring
subject: RNA polymerase dynamics
subject: DDC 570 / Life sciences
subject: DDC 580 / Botanical sciences
subject: RNA polymerases
subject: Single Molecule Imaging
subject: Microscopy, Fluorescence
subject: Haloferax volcanii

description: In recent years, fluorescence microscopy techniques for the localization and tracking of single molecules in living cells have become well-established and are indispensable tools for the investigation of cellular biology and in vivo biochemistry of many bacterial and eukaryotic organisms. Nevertheless, these techniques are still not established for imaging archaea. Their establishment as a standard tool for the study of archaea will be a decisive milestone for the exploration of this branch of life and its unique biology. Here, we have developed a reliable protocol for the study of the archaeon Haloferax volcanii. We have generated an autofluorescence-free H. volcanii strain, evaluated several fluorescent proteins for their suitability to serve as single-molecule fluorescence markers and codon-optimized them to work under optimal H. volcanii cultivation conditions. We found that two of them, Dendra2Hfx and PAmCherry1Hfx, provide state-of-the-art single-molecule imaging. Our strategy is quantitative and allows dual-color imaging of two targets in the same field of view (FOV) as well as DNA co-staining. We present the first single-molecule localization microscopy (SMLM) images of the subcellular organization and dynamics of two crucial intracellular proteins in living H. volcanii cells, FtsZ1, which shows complex structures in the cell division ring, and RNA polymerase, which localizes around the periphery of the cellular DNA. This work should provide incentive to develop SMLM strategies for other archaeal organisms in the near future.
Additional file 8 of Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model
Creators: name: Crépey, Pascal
name: Boiron, Louis
name: Araujo, Rafael Rodrigo
name: Lopez, Juan Guillermo
name: Petitjean, Audrey
name: Expedito José De Albuquerque Luna
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 8 : Table S6. Vaccine efficacy per strain and per age group.
Supplementary document for Near-Perfect Absorber Consisted of Vertical Array of Single-Wall Carbon Nanotubes and Engineered Multi-Wall Carbon Nanotubes - 5152680.pdf
Creators: name: TAHMID, Md Ishfak
name: Mamun, Md Asaduz Zaman
name: Zubair, Ahmed
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary 1
La glossopoiesi: un'eredità culturale per la nostra epoca
Creators: name: Cerbasi, Donato
Publisher: name: Università degli Studi di Milano
Year: 2012

description: In questo articolo intendiamo proporre alcune riflessioni sulla glossopoiesi, con particolare riferimento alla creazione di lingue costruite aposteriori da utilizzare come lingue ausiliarie per la comunicazione internazionale. Accenneremo prima per grandi linee alle lontane radici storiche delfenomeno per poi soffermarci su quella grande stagione del pensiero linguistico europeo che vide all’opera grandi glottoteti tra fine Ottocento e prima metà del Novecento, in modo da prendere in considerazione l’utilità di tale eredità per il nostro attuale mondo globalizzato, specie per quanto concerne le prospettive dell’esperanto, la lingua ausiliaria costruita che meglio ha rettofinora alla prova del tempo.
description: InKoj. Philosophy & Artificial Languages, Vol 3, No 2 (2012): New Languages for new Means of Communication
Restarting Oral Anticoagulant in Patients with Mechanical Heart Valve(s) and Intracranial Haemorrhage
Creators: name: Alkherayf, Fahad
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Mechanical Heart Valve
Intracranial haemorhage
Warfarine
Intracerebral haemohage
Subdural haematoma
Oral anticoagulants
Restarting oral anticoagulants
Systematic review
Survey

description: Patients with mechanical heart valves who present with intracranial haemorrhage are initially treated by reversing their coagulopathy. However, these patients will ultimately require that their oral anticoagulant be restarted. The time at which oral anticoagulants are restarted is critical since restarting too early may increase the risk of recurrent bleeding, while withholding anticoagulants increases the patient’s risk of thromboembolic events. The ideal time to restart patients on their oral anticoagulant medication is defined as the time at which all these risks are minimized. This thesis includes a systematic review and meta-analysis of the literature. The main outcomes were recurrent haematoma, valve thrombosis, stroke and peripheral emboli. Results were stratified by types of intracranial haemorrhage. We also conducted a survey to gain insight into current practices of neurosurgeons and thrombosis experts in Canada and USA when they are faced with deciding on anticoagulant restart times in patients with ICH. Results were stratified by type of intracranial bleed and participants’ characteristics and demographics. The systematic review identified that the ideal time for restarting anticoagulant therapy in patients following an ICH is unknown. Meta-analysis was limited by the heterogeneity of the studies. The survey results indicated that physicians had a wide range of practice and that their practice was dependent on the patient’s clinical features, but many physicians would restart oral anticoagulants between 4 and 14 days after the haemorrhage. For this reason we have proposed a multi centre cohort study to investigate the safety and efficacy of restarting patients on anticoagulation therapy between day 5 and 9 post haemorrhage. A full study protocol is presented in this thesis.
Centrality dependence of charged-hadron transverse-momentum spectra in d + Au collisions at square root SNN = 200 GeV
Creators: name: Back, B. B.
name: Baker, M. D.
name: Ballintijn, M.
name: Barton, D. S.
name: Becker, B.
name: Betts, R. R.
name: Bickley, A. A.
name: Bindel, R
name: Budzanowski, A.
name: Busza, W.
name: Carroll, A. S.
name: Decowski, M. P.
name: Garcia, E. M.
name: Gburek, T.
name: George, N. K.
name: Gulbrandsen, K. H.
name: Gushue, S.
name: Halliwell, C. M.
name: Hamblen, J.
name: Harrington, A. S.
name: Henderson, C.
name: Hofman, D. J.
name: Hollis, R. S.
name: Holynski, R.
name: Holzman, B.
name: Iordanova, A.
name: Johnson, E. E.
name: Kane, J. L.
name: Khan, N.
name: Kulinich, P. A.
name: Kuo, C. M.
name: Lee, J. W.
name: Lin, W. T.
name: Manly, S. L.
name: Mignerey, A. C.
name: Noell, A.
name: Nouicer, R.
name: Olszewski, A.
name: Pak, R.
name: Park, I. C.
name: Pernegger, H.
name: Reed, C.
name: Remsberg, L. P.
name: Roland, C.
name: Roland, G.
name: Sagerer, J.
name: Sarin, P.
name: Sawicki, P.
name: Sedykh, I.
name: Skulski, W.
name: Smith, C. E.
name: Steinberg, P. A.
name: Stephans, G. S. F.
name: Sukhanov, A. V.
name: Teng, R.
name: Tonjes, M. B.
name: Trzupek, A.
name: Vale, C.
name: van Nieuwenhuizen, G. J.
name: Verdier, R.
name: Veres, G. I.
name: Wadsworth, B. F.
name: Wolfs, F. L. H.
name: Wosiek, B.
name: Wozniak, K.
name: Wuosmaa, A. H.
name: Wyslouch, B.
name: Zhang, J.
Publisher: name: Swinburne
Year: 2024

description: We have measured transverse momentum distributions of charged hadrons produced in d+Au collisions at sqrt(s_NN) = 200 GeV. The spectra were obtained for transverse momenta 0.25 < p_T < 6.0 GeV/c, in a pseudorapidity range of 0.2 < eta < 1.4 in the deuteron direction. The evolution of the spectra with collision centrality is presented in comparison to p+pbarcollisions at the same collision energy. With increasing centrality, the yield at high transverse momenta increases more rapidly than the overall particle density, leading to a strong modification of the spectral shape. This change in spectral shape is qualitatively different from observations in Au+Au collisions at the same energy. The results provide important information for discriminating between different models for the suppression of high-p_T hadrons observed in Au+Au collisions.
La città del XXI secolo: dal welfare state alla welfare society
The city of the XXI century: from welfare state to welfare society
Creators: name: Bravo, Luisa; Università Di Bologna
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2008

description: La pianificazione moderna mirava al massimo livello di benessere degli individui e della comunità, modellandosi sulle effettive necessità delle persone: nei vecchi manuali di urbanistica (Rigotti, 1952) compare come appendice al piano regolatore il “Piano dei servizi”, che comprendeva i servizi distribuiti sul territorio circostante, una sorta di piano regolatore sociale, per evitare quartieri separati per fasce di popolazione o per classi. Nella città contemporanea la globalizzazione, le nuove forme di marginalizzazione e di esclusione, l’avvento della cosiddetta New economy, la ridefinizione della base produttiva e del mercato del lavoro sono espressioni di una complessità sociale che può essere definita sulla base delle transazioni e gli scambi simbolici piuttosto che sui processi di industrializzazione e di modernizzazione verso cui era orientata la città storica, adattata alla modernità. Tutto ciò costituisce quel complesso di questioni che attualmente viene definito “nuovo welfare”, in contrapposizione a quello essenzialmente basato sull’istruzione, sulla sanità, sul sistema pensionistico e sull’assistenza sociale.
description: The modern town-planning aimed at maximum level of well-being for individuals and communities, modelling on “real needs of people”: in the old urban systems manuals appears a “Plan of services” as an appendix to the master plan, which includes services distributed on the surrounding areas, a sort of “social master plan” to avoid neighbourhoods separated by segments of population or classes. In the contemporary city globalization, new forms of marginalization and exclusion, the advent of the so-called “new economy”, the re-definition of the production base and the labour market are expression of a social complexity that can be defined trough transactions and symbolic exchanges, rather than trough processes of industrialization and modernization towards which the historic city, adopted into modern, was oriented. All of this questions are the expression of that complex of matters which are currently described as “the new welfare”, opposed to the one essentially based on education, on health, on the pension system and on social assistances.
description: IN_BO. Ricerche e progetti per il territorio, la città e l'architettura; Vol. 0, n. 0 (2008) - NUMERO ZERO; 8 - 19
description: IN_BO. Ricerche e progetti per il territorio, la città e l'architettura; Vol. 0, n. 0 (2008) - NUMERO ZERO; 8 - 19
Dal pixel all'acquerello: la tecnologia NPR nelle illustrazioni di architettura
From pixel to watercoulor: the NPR technology in architectural portraying
Creators: name: Garagnani, Simone; Università Di Bologna
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2008

description: Il progetto in architettura nasce dall’intuizione, concretizzata dapprima con schizzi istintivi atti ad esprimere compiutamente ciò che la parola non riesce a descrivere. Poi i disegni si fanno più dettagliati, recando graficismi e simboli normati per meglio descrivere il particolare. La computer grafica permette di orientare la comunicazione del progetto fino a simulazioni contestualizzate fortemente simili alla realtà. Tale forma di espressione tuttavia non sempre è appropriata, restituendo sovente l’impressione di osservare soluzioni definitive di progetto, mentre in realtà si è pervenuti forse ad una fase di sviluppo dove ancora le alternative sono possibili e dove il realismo digitale non riesce a rendere conto di tutti gli aspetti, anche emozionali, insiti nell’idea da rappresentare. Sono stati sviluppati software indirizzati al rendering non fotorealistico (NPR) per fornire uno strumento flessibile al progettista che vuole raccontare la sua intuizione. In questo  scritto vengono presentati alcuni risultati ottenibili con due programmi NPR specifici: Informatix Piranesi 5 e Autodesk Impression.
description: The Non-Photorealistic Rendering procedure (NPR) is a graphical technique based on the digital reproduction of painting’s effects (pencil, watercolor, engraving, etc.), starting from a raster image. In this paper two NPR software packages will be examined in order to establish how artistic-looking images can improve the architectural design workflow. Informatix Piranesi and Autodesk Impression are dedicated illustration tools used in renderings production from 3D CAD models or from plain 2D drawings in dwg or dwf format.
Additional file 6 of Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model
Creators: name: Crépey, Pascal
name: Boiron, Louis
name: Araujo, Rafael Rodrigo
name: Lopez, Juan Guillermo
name: Petitjean, Audrey
name: Expedito José De Albuquerque Luna
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 6 : Table S4. Life expectancy and utility parameters.
Urbanistica commerciale: commercio, controllo sociale e sicurezza urbana
Creators: name: Angelillo, Donato Ricciotti; Università Di Bologna
name: Veratti, Daniele; IUAV Venezia
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2008

description: The present item is about the contemporary manage and employment of Italian commercial structures, from a general description of different commercial areas to urban safety strategies.The “urban walkway” in analyzed and observed as an urban space recapture process and awareness.
description: Il contributo tenta di porre luce su alcuni aspetti di gestione ed utilizzo delle strutture commerciali italiane, partendo da una breve descrizione delle caratteristiche ordinarie di queste costruzioni, per affrontare il tema (assai delicato e attuale) della sicurezza urbana nelle aree adiacenti agli esercizi stessi.  Il percorso pedonale e l’azione del “camminare” vengono analizzati e interpretati come metodo di riappropriazione dello spazio urbano e della consapevolezza della città, divenendo genesi di senso di territorialità.
The prevalence and clinical characteristics of pertussis-associated pneumonia among infants in Botswana
Creators: name: Abu-Raya, Bahaa
name: Goldfarb, David M.
name: Smieja, Marek
name: Luinstra, Kathy
name: Richard-Greenblatt, Melissa
name: Steenhoff, Andrew P.
name: Feemster, Kristen A.
name: Arscott-Mills, Tonya
name: Cunningham, Coleen K.
name: Shah, Samir S.
name: Patel, Mohamed Z.
name: Kelly, Matthew S.
name: Sadarangani, Manish
Publisher: name: BioMed Central
Year: 2019

description: Background: There are scant data on the prevalence and clinical course of pertussis disease among infants with pneumonia in low- and middle-income countries. While pertussis vaccination coverage is high (≥90%) among infants in Botswana, human immunodeficiency virus (HIV) infection affects nearly one-third of pregnancies. We aimed to evaluate the prevalence and clinical course of pertussis disease in a cohort of HIV-unexposed uninfected (HUU), HIV-exposed uninfected (HEU), and HIV-infected infants with pneumonia in Botswana. Methods: We recruited children 1–23 months of age with clinical pneumonia at a tertiary care hospital in Gaborone, Botswana between April 2012 and June 2016. We obtained nasopharyngeal swab specimens at enrollment and tested these samples using a previously validated in-house real-time PCR assay that detects a unique sequence of the porin gene of Bordetella pertussis. Results: B. pertussis was identified in 1/248 (0.4%) HUU, 3/110 (2.7%) HEU, and 0/33 (0.0%) HIV-infected children. All pertussis-associated pneumonia cases occurred in infants 1–5 months of age (prevalence, 1.0% [1/103] in HUU and 4.8% [3/62] in HEU infants). No HEU infants with pertussis-associated pneumonia were taking cotrimoxazole prophylaxis at the time of hospital presentation. One HUU infant with pertussis-associated pneumonia required intensive care unit admission for mechanical ventilation, but there were no deaths. Conclusions: The prevalence of pertussis was low among infants and young children with pneumonia in Botswana. Although vaccination against pertussis in pregnancy is designed to prevent classical pertussis disease, reduction of pertussis-associated pneumonia might be an important additional benefit.
Does emotional intelligence mediate the relationship between conflict and relationship satisfaction in romantic relationships?
Creators: name: McCarthy, Breeanna
Publisher: name: Swinburne
Year: 2024

description: The current study explored the relationship between Emotional Intelligence (EI), Relationship Conflict and Relationship Satisfaction in romantic relationships. The sample comprised 179 participants who were all in heterosexual relationships, 123 females (M =29.04 years, SD = 13.08 years), 55 males (M= 32.84 years, SD = 11.19 years). Participants responded to a self report questionnaire. Partial support was found for the hypothesis that on average, participants with higher levels of General and Positive Relationship Satisfaction and lower levels of Negative Relationship Satisfaction, would engage more in effective and less in ineffective conflict resolution styles, and argue ineffectively less frequently with their partners. The hypothesis that on average, participants with a high level of EI would have a higher level of General and Positive Relationship Satisfaction and a lower level of Negative Relationship Satisfaction, than those with low EI, was also partially supported. The findings also partially supported the hypothesis that on average, participants of high EI would engage more in effective and less in ineffective conflict resolution styles, and argue ineffectively less frequently with their partners. Overall, partial support was found for the exploratory question which investigated whether a participant’s level of EI would mediate the relationship between the participant’s level of Relationship Conflict and Relationship Satisfaction. It was concluded that the current findings contribute to the growing body of research on EI and more specifically, support the importance of EI in social relationships. The current study provides preliminary evidence for the direct relationship between EI, Conflict and Relationship Satisfaction and particularly, partially supports the contention that EI mediates the relationship between Conflict and Satisfaction in romantic relationships.
Additional file 7 of Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model
Creators: name: Crépey, Pascal
name: Boiron, Louis
name: Araujo, Rafael Rodrigo
name: Lopez, Juan Guillermo
name: Petitjean, Audrey
name: Expedito José De Albuquerque Luna
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 7 : Table S5. Cost parameters used in the economic model.
Lettura fenomenologica e progetto di paesaggio
Creators: name: Bortolotti, Alberto; Università Di Bologna
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2008

description: La precarietà degli equilibri paesistici nel nostro tempo, la natura sempre più instabile degli ambiti suburbani ne è il più chiaro esempio, negli ultimi anni ha riportato al centro dell’attenzione di architetti, urbanisti e sociologi, il tema di un  progetto di paesaggio connesso alle pratiche di pianificazione  territoriale. Ciò ha posto il problema della necessità di  considerare le trasformazioni non soltanto in termini di effetti  misurabili quantitativamente, ma  anche rispetto a condizioni che appartengono più qualitativamente  alla sfera emotiva di un abitante o di un visitatore, che dei luoghi  in via di trasformazione fanno potenzialmente uso. Su tale aspetto emozionale del modo di abitare e di fare uso dello spazio, si fonda il senso comune di identificazione in una realtà costruita intesa come paesaggio.
Vaccine side effects in health care workers after vaccination against SARS-CoV-2: data from TüSeRe:exact study
Creators: name: Bareiß, Alan
name: Uzun, Günalp
name: Mikus, Marco
name: Becker, Matthias
name: Althaus, Karina
name: Schneiderhan-Marra, Nicole
name: Fürstberger, Axel
name: Schwab, Julian D.
name: Kestler, Hans A.
name: Holderried, Martin
name: Martus, Peter
name: Schenke-Layland, Katja
name: Bakchoul, Tamam
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: vaccine
subject: reactogenicity
subject: adverse event
subject: DDC 610 / Medicine & health
subject: COVID-19 vaccines; Adverse effects
subject: COVID-19
subject: Impfung
subject: Nebenwirkung

description: As the Corona Disease 2019 (COVID-19) caused by SARS-CoV-2 persists, vaccination is one of the key measures to contain the spread. Side effects (SE) from vaccination are one of the reasons for reluctance to vaccinate. We systematically investigated self-reported SE after the first, second, and booster vaccinations. The data were collected during the TüSeRe: exact study (Tübinger Monitoring Studie zur exakten Analyse der Immunantwort nach Vakzinierung). Employees of health and research institutions were invited to participate. Study participants were asked to fill out an online questionnaire and report their SE after each dose of SARS-CoV-2 vaccination. A total of 1046 participants (mean age: 44 ± 12.9 years; female, n = 815 (78%); male, n = 231 (22%)) were included in the analysis. Local and systemic SE were more frequent after receiving the vector-based vaccine ChAdOx1 nCoV-19 in the first vaccination. However, local and systemic SE were more common after receiving mRNA vaccines (BNT162b2, mRNA-1273) in the second vaccination. Compared to the BNT162b2 vaccine, more SE have been observed after receiving the mRNA-1273 vaccine in the booster vaccination. In multivariate analysis, local and systemic side effects were associated with vaccine type, age and gender. Local and systemic SE are common after SARS-CoV-2 vaccines. The frequency of self-reported local and systemic SE differ significantly between mRNA and vector-based vaccines.