cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effects of cocoa on altered metabolite levels in purine metabolism pathways and urea cycle in Alzheimer's disease in C. elegans
Creators: name: Munasinghe, Mihiri
name: Afshari, Roya
name: Heydarian, Deniz
name: Almotayri, Abdullah
name: Dias, Daniel A
name: Thomas, Jency
name: Jois, Markandeya
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3205
subject: Medical biochemistry and metabolomics

description: Dietary interventions have gained much attention as alternative therapies in aging-associated diseases. Epidemiological studies suggest that polyphenols (PPs) play an important role in this regard. Cocoa is rich in PPs, greater in amount than in teas and red wine. This study aimed to characterize the age-associated and amyloid-β (Aβ)-induced changes in metabolism in C. elegans and the effects of cocoa supplementation. An untargeted Gas Chromatography-Mass Spectrometry (GC-MS) approach was used to determine the changes in endogenous metabolite levels in wild-type and a transgenic C. elegans strain expressing pan-neuronal Aβ (GRU102). Aging appeared to alter some amino acid levels in C. elegans. Cocoa supplementation reduced leucine and tyrosine levels in old age (day 12). GRU102 showed higher proline and asparagine relative to control worms at a young age (day 4) which may have a connection with cognitive deficits in Alzheimer's disease (AD). Cocoa reduced the elevated levels of these two amino acids to the levels in the control worms. The purine derivative, hypoxanthine was higher in GRU102 relative to the control worms at their middle age (day 8) where the elevated are known to contribute to memory deficits in AD. Cocoa supplementation reduced the elevated hypoxanthine to normal levels. Aβ expression showed alterations in the urea cycle in worms in their middle age as indicated by increased ornithine.
Additional file 1 of A simple and effective method for simulating nested exchangeable correlated binary data for longitudinal cluster randomised trials
Creators: name: Bowden, Rhys A.
name: Kasza, Jessica
name: Forbes, Andrew B.
Publisher: name: figshare
Year: 2024
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Supplementary Material 1.
Supplementary document for 0.1THz super-resolution imaging based on confocal waveguide and slider-crank - 6416695.pdf
Creators: name: Wang, Zhengxin
name: Li, Xinyu
name: wang, Qianwen
name: Gong, Cheng
name: Liu, Weiwei
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Photograph of the system
title: Ballet Ballads: Experimental Theatre Ends Its Season With Three Brief Musical Sketches
Creators: name: Atkinson, Brooks
Publisher: name: George Mason University
Year: 1997
Subjects: subject: Ballet Ballads
subject: Experimental Theatre
subject: ANTA
subject: American Theatre Wing
subject: Latouche, John
subject: Moross, Jerome
subject: Litz, Katherine
subject: Godkin, Paul
subject: Holm, Hanya
subject: Martin, John
subject: Garfield, John
subject: Dowling, Eddie
subject: Harrity, Richard
subject: Gilbert, Lou
subject: Ayers, Catherine
subject: Karson, Nat
subject: Hunter, Mary

description: Theater review.
description: Clipping.
KARYER BORTLARI TURG'UNLIGINING GEOMEXANIK HOLATINI BAHOLASHDA TEKTONIK OMILLAR TA'SIRINING TAHLILI
Creators: name: Kadirov, V.R.
name: Kushnazorov, I.S.
name: Mamirov, J.X.
name: Nurmamatov, D.O.
name: Jovqonov, A.Sh.
Publisher: name: Zenodo
Year: 2024

description: Maqolada karyer borti turg‘unligiga tektonik omillarning ta’siri o‘rganilgan. Bort turg‘unligining geomexanik holatini baholashda litosfera qobig‘ida sodir bo‘ladigan tektonik jarayonlar turlari o‘rganilgan. Karyer borti massivida deformatsiya sodir bo‘lishiga tektonik jarayonlarning ko‘rsatadigan ta’siri keltirilgan. Bundan tashqari tektonik omillar hosilasi hisoblangan darzliklar orqali massivga ta’sir etuvchi yer osti va usti suvlarining bortning geomexanik holatiga ta’siri keltirib o‘tilgan.
Effects of cocoa on altered metabolite levels in purine metabolism pathways and urea cycle in Alzheimer's disease in C. elegans
Creators: name: Munasinghe, Mihiri
name: Afshari, Roya
name: Heydarian, Deniz
name: Almotayri, Abdullah
name: Dias, Daniel A
name: Thomas, Jency
name: Jois, Markandeya
Publisher: name: La Trobe
Year: 2022

description: Dietary interventions have gained much attention as alternative therapies in aging-associated diseases. Epidemiological studies suggest that polyphenols (PPs) play an important role in this regard. Cocoa is rich in PPs, greater in amount than in teas and red wine. This study aimed to characterize the age-associated and amyloid-β (Aβ)-induced changes in metabolism in C. elegans and the effects of cocoa supplementation. An untargeted Gas Chromatography-Mass Spectrometry (GC-MS) approach was used to determine the changes in endogenous metabolite levels in wild-type and a transgenic C. elegans strain expressing pan-neuronal Aβ (GRU102). Aging appeared to alter some amino acid levels in C. elegans. Cocoa supplementation reduced leucine and tyrosine levels in old age (day 12). GRU102 showed higher proline and asparagine relative to control worms at a young age (day 4) which may have a connection with cognitive deficits in Alzheimer's disease (AD). Cocoa reduced the elevated levels of these two amino acids to the levels in the control worms. The purine derivative, hypoxanthine was higher in GRU102 relative to the control worms at their middle age (day 8) where the elevated are known to contribute to memory deficits in AD. Cocoa supplementation reduced the elevated hypoxanthine to normal levels. Aβ expression showed alterations in the urea cycle in worms in their middle age as indicated by increased ornithine.
Additional file 1 of Trends and socioeconomic inequalities in the dental attendance of adult smokers in Scotland from 2009 to 2019, a repeated cross-sectional study
Creators: name: Warner, Frances E.
name: Sherriff, Andrea
name: Culshaw, Shauna
name: Holliday, Richard
name: Ryan, Vicky
name: Conway, David I.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Cancer
Science Policy
Mental Health

description: Supplementary Material 1
title: Newspaper Column: Janet Howell vs. Rosie Scenario
Creators: name: Nicoson, William J.
Publisher: name: Reston Times
Year: 2001
Subjects: subject: Howell, Janet
subject: Gilmore, James S. (James Stuart), 1949-
subject: Virginia (Treasury)
subject: Virginia (Budget)

description: PDF file distilled from original WordPerfect document. Original size 11" x 8.5".
description: Reston’s state senator, Janet Howell (D), usually a model of bipartisan gentility, is waging a relentless, no-holds-barred battle against that soothing doyenne of happy days, Rosie Scenario. Senator Howell believes that Governor James S. Gilmore III has recruited Rosie to mislead Restonians and other Virginians into believing that all’s well with the state of the state’s treasury and budget.
Exploring the relevance and applicability of the irecs training materials on emerging technologies for diverse cultural and regulatory contexts through reflective interviews
Creators: name: Pallise Perello, Claudia
name: Inguaggiato, Giulia
name: Berentsen, Susan
name: Evans, Natalie
name: van den Hoven, Mariëtte
Publisher: name: Zenodo
Year: 2025

description: Pr
The healthcare needs and general practice utilization of people with acquired neurological disability and complex needs: A scoping review
Creators: name: Oliver, Stacey
name: Douglas, Jacinta
name: Winkler, Dianne
name: Pearce, C
name: Minter, ER
name: Jarman, Hannah
name: Topping, Megan Ciara
Publisher: name: La Trobe
Year: 2023

description: Background: For people with acquired neurological disabilities and complex needs, general practitioners (GPs) play an important role in health management and early intervention for the prevention of comorbidities and health complications. People with disability are a vulnerable group who need and have the right to, quality general practice services. It is therefore important to understand the health needs and service use of this group. The aim of this review was to identify the healthcare needs and general practice utilization of people with acquired neurological disabilities and complex needs. Methods: A scoping review methodological framework was utilized. Six databases (MEDLINE, PsycInfo, CINAHL, Scopus, Embase and the Cochrane Library) were searched. Articles were included if they reported on general practice service utilization of people with acquired neurological disabilities and complex needs aged between 18 and 65. Articles were required to be peer-reviewed, written in English and published between 2010 and 2021. Results: Thirty-one articles were included in the review. Studies originated from Canada (9), the United States (8), Australia (4), Switzerland (4), the United Kingdom (2), England (1), Norway (1), France (1) and Denmark (1). For many people, GPs were the main healthcare provider. People with disability consult multiple healthcare providers and navigate complex healthcare systems. Commonly presented healthcare needs were bladder, bowel and skin problems, pain and chronic pain, medication needs and mental health concerns. Conclusions: People with acquired neurological disabilities and complex needs were vulnerable to receiving suboptimal healthcare. The literature highlighted issues regarding the accessibility of services, the fragmentation of health services and inadequate preventative care. GPs were challenged to offer adequate disability-related expertise and to meet the mental health needs of people with disability within time constraints. Patient and Public Involvement: This manuscript was prepared in collaboration with a GP, who is one of the authors. A person with lived experience of acquired neurological disability was engaged to check the alignment of the findings with their personal experience and provide feedback.
The healthcare needs and general practice utilization of people with acquired neurological disability and complex needs: A scoping review
Creators: name: Oliver, Stacey
name: Douglas, Jacinta
name: Winkler, Dianne
name: Pearce, C
name: Minter, ER
name: Jarman, Hannah
name: Topping, Megan Ciara
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 4206
subject: Public health

description: Background: For people with acquired neurological disabilities and complex needs, general practitioners (GPs) play an important role in health management and early intervention for the prevention of comorbidities and health complications. People with disability are a vulnerable group who need and have the right to, quality general practice services. It is therefore important to understand the health needs and service use of this group. The aim of this review was to identify the healthcare needs and general practice utilization of people with acquired neurological disabilities and complex needs. Methods: A scoping review methodological framework was utilized. Six databases (MEDLINE, PsycInfo, CINAHL, Scopus, Embase and the Cochrane Library) were searched. Articles were included if they reported on general practice service utilization of people with acquired neurological disabilities and complex needs aged between 18 and 65. Articles were required to be peer-reviewed, written in English and published between 2010 and 2021. Results: Thirty-one articles were included in the review. Studies originated from Canada (9), the United States (8), Australia (4), Switzerland (4), the United Kingdom (2), England (1), Norway (1), France (1) and Denmark (1). For many people, GPs were the main healthcare provider. People with disability consult multiple healthcare providers and navigate complex healthcare systems. Commonly presented healthcare needs were bladder, bowel and skin problems, pain and chronic pain, medication needs and mental health concerns. Conclusions: People with acquired neurological disabilities and complex needs were vulnerable to receiving suboptimal healthcare. The literature highlighted issues regarding the accessibility of services, the fragmentation of health services and inadequate preventative care. GPs were challenged to offer adequate disability-related expertise and to meet the mental health needs of people with disability within time constraints. Patient and Public Involvement: This manuscript was prepared in collaboration with a GP, who is one of the authors. A person with lived experience of acquired neurological disability was engaged to check the alignment of the findings with their personal experience and provide feedback.
Additional file 1 of The symptoms evolution of long COVID‑19 (SE-LC19): a new patient-reported content valid instrument
Creators: name: Rofail, Diana
name: Somersan-Karakaya, Selin
name: Mylonakis, Eleftherios
name: Choi, Julia Y.
name: Przydzial, Krystian
name: Marquis, Sarah
name: Zhao, Yuming
name: Hussein, Mohamed
name: Norton, Thomas D.
name: Podolanczuk, Anna J.
name: Geba, Gregory P.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
Additional file 1 of Pozelimab for CHAPLE disease: results from in-trial interviews and clinical outcome assessments
Creators: name: Litcher-Kelly, Leighann
name: Ozen, Ahmet
name: Ollis, Sarah
name: Feldman, Hagit Baris
name: Yaworsky, Andrew
name: Medrano, Paolo
name: Chongsrisawa, Voranush
name: Brackin, Taylor
name: Perlee, Lorah
name: Walker, Marisa
name: Pradeep, Sharanya
name: Lenardo, Michael J.
name: Harari, Olivier A.
name: Jalbert, Jessica J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Scalable Generation of Nanovesicles from Human-Induced Pluripotent Stem Cells for Cardiac Repair
Creators: name: LOZANO SALGADO, Jonathan
name: Rai, Alin
name: Lees, JG
name: Fang, H
name: Claridge, Bethany
name: Lim, SY
name: Greening, David
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3107
subject: Microbiology
classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3404
subject: Medicinal and biomolecular chemistry

description: Extracellular vesicles (EVs) from stem cells have shown significant therapeutic potential to repair injured cardiac tissues and regulate pathological fibrosis. However, scalable generation of stem cells and derived EVs for clinical utility remains a huge technical challenge. Here, we report a rapid size-based extrusion strategy to generate EV-like membranous nanovesicles (NVs) from easily sourced human iPSCs in large quantities (yield 900× natural EVs). NVs isolated using density-gradient separation (buoyant density 1.13 g/mL) are spherical in shape and morphologically intact and readily internalised by human cardiomyocytes, primary cardiac fibroblasts, and endothelial cells. NVs captured the dynamic proteome of parental cells and include pluripotency markers (LIN28A, OCT4) and regulators of cardiac repair processes, including tissue repair (GJA1, HSP20/27/70, HMGB1), wound healing (FLNA, MYH9, ACTC1, ILK), stress response/translation initiation (eIF2S1/S2/S3/B4), hypoxia response (HMOX2, HSP90, GNB1), and extracellular matrix organization (ITGA6, MFGE8, ITGB1). Functionally, NVs significantly promoted tubule formation of endothelial cells (angiogenesis) (p < 0.05) and survival of cardiomyocytes exposed to low oxygen conditions (hypoxia) (p < 0.0001), as well as attenuated TGF-β mediated activation of cardiac fibroblasts (p < 0.0001). Quantitative proteome profiling of target cell proteome following NV treatments revealed upregulation of angiogenic proteins (MFGE8, MYH10, VDAC2) in endothelial cells and pro-survival proteins (CNN2, THBS1, IGF2R) in cardiomyocytes. In contrast, NVs attenuated TGF-β-driven extracellular matrix remodelling capacity in cardiac fibroblasts (ACTN1, COL1A1/2/4A2/12A1, ITGA1/11, THBS1). This study presents a scalable approach to generating functional NVs for cardiac repair.
title: Fair and Comprehensive Comparison of Hardware Performance of SHA-3 Round 2 Candidates Using FPGAs
Creators: name: Homsirikamol, Ekawat
Publisher: name: George Mason University
Year: 2010
Subjects: subject: FPGA
subject: Performance evaluation
subject: SHA
subject: Hash

description: In 2007, National Institute of Standards and Technology has announced a contest for a new American cryptographic hash function standard, called SHA-3. At the time of writing, after eliminating 37 algorithms in Round 1, due to security and performance weaknesses, only 14 Round 2 candidate algorithms remain in the competition. A comprehensive methodology for fair comparison of hash algorithms competing in the SHA-3 contest from the point of view of hardware performance in FPGAs has been proposed in this thesis. Based on this methodology, hardware designs optimized for the maximum throughput to area ratio have been developed for all Round 2 SHA-3 candidates. The obtained results have been compared with results from other groups. In our study, only three candidates, namely CubeHash, Keccak and Lu a, have consistently outperformed SHA-2 in terms of the throughput to area ratio for both 256 and 512 bits versions of all hash algorithms.
Continuity of temperament subgroup classifications from infancy to toddlerhood in the context of early autism traits
Creators: name: Chetcuti, Lacey
name: Uljarevic, Mirko
name: Varcin, KJ
name: Boutrus, M
name: Dimov, S
name: Pillar, S
name: Barbaro, Josephine
name: Dissanayake, Cheryl
name: Green, J
name: Whitehouse, AJO
name: Hudry, Kristelle
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 3209
subject: Neurosciences
subject: FOS: Clinical medicine
classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5201
subject: Applied and developmental psychology
classificationCode: 5203
subject: Clinical and health psychology
classificationCode: 5205
subject: Social and personality psychology

description: Our previous cross-sectional investigation (Chetcuti et al., 2020) showed that infants with autism traits could be divided into distinct subgroups based on temperament. This longitudinal study builds on this existing work by exploring the continuity of temperament subgroup classifications and their associations with behavioral/clinical phenotypic features from infancy to toddlerhood. 103 infants (68% male) showing early signs of autism were referred to the study by community healthcare professionals and seen for assessments when aged around 12-months (Time 1), 18-months (Time 2), and 24-months (Time 3). Latent profile analysis revealed inhibited/low positive, active/negative reactive, and sociable/well-regulated subgroups at each timepoint, and a unique reactive/regulated subgroup at Time 3. Cross-tabulations indicated a significant likelihood of children having a recurrent subgroup classification from one timepoint to the next, and no apparent patterns to the movement of children who did change from one subgroup to another over time. Temperament subgroups were associated with concurrent child social–emotional functioning and autism traits, but unrelated to child age, sex, or developmental level. These findings suggest that temperament subgroup classifications might represent a reliable and very early indicator of autism characteristics and social–emotional functioning among infants/toddlers with autism traits.
"Che hoah unan, Marionig" (En voilà encore une, Maryvonne). Formule de fin de chanson à ritournelle
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2024

Abstract
title: Flyer: Mason Campus Final Four Watch Parties, ca. March, 2006
Creators: name: University, George Mason
Publisher: name: George Mason University
Year: 2006
Subjects: subject: George Mason University
subject: Basketball
subject: Final Four
subject: National Collegiate Athletic Association (NCAA)

description: Flyer: color, 8.5" x 11" (21.6 cm x 27.9 cm)
description: Flyer for Final Four watch parties occurring on the Mason campus. 2005-06 Men's Basketball Season and Tournament Run Collection 1.05
DRL-Based Secure Beamforming for Hybrid-RIS Aided Satellite Downlink Communications
Creators: name: Ngo, Quynh Tu
name: Phan, Tran Khoa
name: Mahmood, Abdun
name: Xiang, Wei
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 40
subject: Engineering
classificationCode: 4006
subject: Communications engineering
classificationCode: 46
subject: Information and computing sciences
classificationCode: 4613
subject: Theory of computation

description: No description supplied
Additional file 1 of HPV integration: a precise biomarker for detection of residual/recurrent disease after treatment of CIN2-3
Creators: name: Huang, Fanwei
name: He, Liang
name: Li, Wei
name: Huang, Xiaoyuan
name: Zhang, Tao
name: Muaibati, Munawaer
name: Zhou, Hu
name: Chen, Shimin
name: Yang, Wenhui
name: Yang, Fan
name: Zhuang, Liang
name: Hu, Ting
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1.
Pyjamas, Polysomnography and Professional Athletes: The Role of Sleep Tracking Technology in Sport
Creators: name: Driller, Matthew
name: Dunican, Ian C
name: Omond, Shauni
name: Boukhris, Omar
name: Stevenson, Shauna
name: Lambing, Kari
name: Bender, Amy M
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4207
subject: Sports science and exercise

description: Technological advances in sleep monitoring have seen an explosion of devices used to gather important sleep metrics. These devices range from instrumented ‘smart pyjamas’ through to at-home polysomnography devices. Alongside these developments in sleep technologies, there have been concomitant increases in sleep monitoring in athletic populations, both in the research and in practical settings. The increase in sleep monitoring in sport is likely due to the increased knowledge of the importance of sleep in the recovery process and performance of an athlete, as well as the well-reported challenges that athletes can face with their sleep. This narrative review will discuss: (1) the importance of sleep to athletes; (2) the various wearable tools and technologies being used to monitor sleep in the sport setting; (3) the role that sleep tracking devices may play in gathering information about sleep; (4) the reliability and validity of sleep tracking devices; (5) the limitations and cautions associated with sleep trackers; and, (6) the use of sleep trackers to guide behaviour change in athletes. We also provide some practical recommendations for practitioners working with athletes to ensure that the selection of such devices and technology will meet the goals and requirements of the athlete.
La redazione definitiva della "Bassvilliana" e il suo testo critico
Creators: name: Biancardi, Giovanni
Publisher: name: Prassi Ecdotiche della Modernità Letteraria
Year: 2016
Subjects: Vincento Monti; Monti; Bassvilliana; edizione critica; testo critico; redazione definitiva

description: (in attesa di caricamento del contributo)
description: Prassi Ecdotiche della Modernità Letteraria, N. 1 (2016)
Quattro edizioni degli "Amori" di Ludovico Savioli
Creators: name: Tanzi Imbri, Barbara
Publisher: name: Prassi Ecdotiche della Modernità Letteraria
Year: 2016
Subjects: Ludovico Savioli; Savioli; edizioni; Remondini; varianti; stampa

description: (in attesa di caricamento del contributo)
description: Prassi Ecdotiche della Modernità Letteraria, N. 1 (2016)
Endometrial small extracellular vesicles regulate human trophectodermal cell invasion by reprogramming the phosphoproteome landscape
Creators: name: Fatmous, Monique
name: Rai, Alin
name: Poh, Qi Hui
name: Salamonsen, LA
name: Greening, David
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3215
subject: Reproductive medicine

description: A series of cyclical events within the uterus are crucial for pregnancy establishment. These include endometrial regeneration following menses, under the influence of estrogen (proliferative phase), then endometrial differentiation driven by estrogen/progesterone (secretory phase), to provide a microenvironment enabling attachment of embryo (as a hatched blastocyst) to the endometrial epithelium. This is followed by invasion of trophectodermal cells (the outer layer of the blastocyst) into the endometrium tissue to facilitate intrauterine development. Small extracellular vesicles (sEVs) released by endometrial epithelial cells during the secretory phase have been shown to facilitate trophoblast invasion; however, the molecular mechanisms that underline this process remain poorly understood. Here, we show that density gradient purified sEVs (1.06–1.11 g/ml, Alix+ and TSG101+, ∼180 nm) from human endometrial epithelial cells (hormonally primed with estrogen and progesterone vs. estrogen alone) are readily internalized by a human trophectodermal stem cell line and promote their invasion into Matrigel matrix. Mass spectrometry-based proteome analysis revealed that sEVs reprogrammed trophectoderm cell proteome and their cell surface proteome (surfaceome) to support this invasive phenotype through upregulation of pro-invasive regulators associated with focal adhesions (NRP1, PTPRK, ROCK2, TEK), embryo implantation (FBLN1, NIBAN2, BSG), and kinase receptors (EPHB4/B2, ERBB2, STRAP). Kinase substrate prediction highlighted a central role of MAPK3 as an upstream kinase regulating target cell proteome reprogramming. Phosphoproteome analysis pinpointed upregulation of MAPK3 T204/T202 phosphosites in hTSCs following sEV delivery, and that their pharmacological inhibition significantly abrogated invasion. This study provides novel molecular insights into endometrial sEVs orchestrating trophoblast invasion, highlighting the microenvironmental regulation of hTSCs during embryo implantation.
title: A Study on the Solo Piano Pieces of Jiesun Lim: Spiritual Dance (2004), Ice Flower (2006), A Poem about Spring (2008), And Fantasia on a Theme of Chopin (2009)
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2021

description: Jiesun Lim is a composer who is considered to be one of the most prominent contemporary musicians in Korea. This dissertation investigates the stylistic features of Lim’s four solo piano works: Spiritual Dance, Ice Flower, A Poem about Spring, and Fantasia on a Theme of Chopin. To provide context and aid understanding of the characteristics of the composer, this dissertation provides some background on Korean musical contemporary music and discusses overall characteristics of Jiesun Lim’s major works. This will be followed by a detailed analysis of the four solo piano works. The analysis concentrates on the examination of forms, harmonies, melodies, rhythms, and keyboard usages in each of Lim’s solo piano works. By undertaking an overview of Jiesun Lim’s piano work and an in-depth analysis of her solo music, I wanted to improve my overall understanding of the composer and her musical world. In addition, I hope that follow-up research on Lim and her music will continue actively in the future, and that her works will have the opportunity to reach more performers and a wider audience.
Additional file 1 of Bimetallic MOF-based electrochemical sensor for determination of paracetamol in spiked human plasma
Creators: name: Mouhamed, Aya A.
name: Nadim, Ahmed H.
name: Mahmoud, Amr M.
name: Mostafa, Nadia M.
name: Eltanany, Basma M.
Publisher: name: figshare
Year: 2024
Subjects: Biochemistry
Space Science
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified

description: Supplementary Material 1
Art therapy and eating disorders: A mixed methods feasibility study
Creators: name: Griffin, Caryn
name: Fenner, Patricia
name: Landorf, Karl
name: Cotchett, Matthew
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 3604
subject: Performing arts
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 4203
subject: Health services and systems
classificationCode: 5203
subject: Clinical and health psychology

description: No description supplied
La farsa del burqini: ma c’è un giudice a Parigi!
Creators: name: Casuscelli, Giuseppe
Publisher: name: Università degli Studi di Milano
Year: 2016
Subjects: Editoriale

description: "A CHIARE LETTERE” – TRANSIZIONI
description: Stato, Chiese e pluralismo confessionale, 2016: 12 settembre
Per un’equa mondializzazione delle periferie nelle società plurali: un ‘nuovo’ Corso di laurea sull’interculturalità
Creators: name: Berlingò, Salvatore
Publisher: name: Università degli Studi di Milano
Year: 2016
Subjects: Laicità e pluralismo

description: Contributo non sottoposto a valutazione.Il saggio, con l’originario titolo integrale Per una equa mondializzazione delle periferie nelle società plurali. La lunga (ma, forse, istruttiva) storia dell’attivazione di un ‘nuovo’ Corso di laurea sull’interculturalità, è destinato agli Studi in onore del Prof. Mario Tedeschi, ed è altresì inserito fra i contributi ai lavori della Prima Sessione del Convegno Diritto e religioni. Declinazioni della giuridicità nel contesto di una società multiculturale e multireligiosa, organizzato in data 1-2 dicembre 2016 dalla Prof.ssa Beatrice Serra presso l’Università degli Studi di Roma La Sapienza
SOMMARIO: 1. Il vortice iperbolico del bacino euromediterraneo e il ‘bergamotto dell’interculturalità’ - 2. Il ‘made in Italy’ dantesco e il doppio registro delle Università per stranieri nel “bel paese là dove ‘l sì suona“ - 3. Il ‘bisogno di mondo’ e la rifrazione in alto dell’identità plurale della Calabria - 4. L’imperativo del ‘Mare Amoroso’ e gli ‘ottativi categorici’ mirati a una sostanziale e concreta giustizia - 5. Dante prima e oltre Kant: dalla ‘giustizia della carità’ alla ‘carità della giustizia’ - 6. Ancora: di un’inedita sperimentazione accademica e civile.

 ABSTRACT: For a fair globalization of the suburbs in plural societies: a 'new' Bachelor's Degree in Interculturality.
With this essay the author, actually Rector of the University for Foreigners "Dante Alighieri" of Reggio Calabria, is to illustrate the steps that have led to the activation of a Bachelor's Degree (in some respects) innovative, induced by contemporary issues of migration flows and by the dynamics of international mobility, become remarkably more rapid and pressing in conjunction with the related phenomena of globalization. They impose, even to the higher education institutes, a timely and in-depth rethinking and an accurate taking of responsibility, with the respect to their relevant areas of teaching and training program. The trial that is intended to give through the above-mentioned Degree was modeled on the basis of some previous initiatives, taken by the University for Foreigners of Reggio Calabria, even if the model now proposed benefits from the innovative results induced by synergies with other Universities for Foreigners, in particular that of Siena, as well as the consultation put in place with the Ministry of Education, the Interior Ministry and the EU, and the cooperation with civil society organizations, primarily the Community of Sant'Egidio.
description: Stato, Chiese e pluralismo confessionale, 2016: 12 settembre
Il Comitato europeo dei diritti sociali, lo stato di attuazione della legge italiana sulla tutela sociale della maternità e sull’interruzione volontaria della gravidanza e la sostenibilità pubblica dell'obiezione di coscienza
Creators: name: Cembriani, Fabio
Publisher: name: Università degli Studi di Milano
Year: 2016
Subjects: Obiezioni di coscienza

description: Contributo non sottoposto a valutazi
SOMMARIO: 1. Introduzione - 2. I diritti sociali in Europa e il Comitato europeo sui diritti sociali (CEDS) - 3. Le decisioni di merito del Comitato europeo dei diritti sociali sull’attuazione nel nostro Paese della legge n. 194 del 1978 - 4. L’obiezione di coscienza e l’interruzione volontaria della gravidanza in Italia - 5. Le strade possibili per dare una sostenibilità pubblica all’obiezione di coscienza - 6. Alcune brevi considerazioni di sintesi.
 SUMMARY: The author examines the decision of the European Committee of Social Rights (CEDS), which once again condemned Italy had not taken our country, compared to the large number of doctors objectors, no organizational measures to ensure the reproductive rights of women and the right to work of non-objectors. He thus addresses the issue of social rights in Europe and the role of guarantor of the CEDS to focus eventually on conscientious objection, which considers a fundamental right, which must, however, know how to give, not interfere collectability of other rights. Moreover, it indicates, finally, what are the possible ways to give concrete and practical sustainability of conscientious objection.
description: Stato, Chiese e pluralismo confessionale, 2016: 12 settembre
Exploring the Relationship between Polymer Surface Chemistry and Bacterial Attachment Using ToF-SIMS and Self-Organizing maps
Creators: name: Wong, See Yoong
name: Hook, Andrew
name: Gardner, Wil
name: Chang, Chienyi
name: Mei, Ying
name: Davies, Martyn
name: Williams, Paul
name: Alexander, Morgan
name: Ballabio, Davide
name: Muir, Benjamin
name: Winkler, David
name: Pigram, Paul
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 340201
subject: Bioinorganic chemistry
classificationCode: 3403
subject: Macromolecular and materials chemistry
classificationCode: 4016
subject: Materials engineering
subject: FOS: Materials engineering
classificationCode: 5104
subject: Condensed matter physics

description: No description supplied
A telomere-to-telomere genome of Phellodendron amurense reveals insights into berberine biosynthesis
Creators: name: Chen, Song
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310509
subject: Genomics

description: Phellodendron amurense is a Tertiary relict species with significant ecological and medicinal value. Here, we present a Telomere-to-Telomere (T2T) genome assembly of P. amurense, revealing a large genome of 2.94 Gb distributed across 39 chromosomes.
Additional file 1 of What caused the record-low frequency of western North Pacific tropical cyclones in autumn 2023?
Creators: name: Song, Jinjie
name: Klotzbach, Philip J.
name: Wei, Na
name: Duan, Yihong
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Plant Biology

description: Supplementary Material 1.
La laicità e l’integrazione sociale: un rapporto ambiguo
Creators: name: Macioce, Fabio
Publisher: name: Università degli Studi di Milano
Year: 2016
Subjects: Laicità e pluralismo

description: Contributo sottoposto a valutazione.
SOMMARIO: 1. Introduzione – 2. L’orizzonte sociale di riferimento: a) la presenza pubblica delle religioni e la super-diversità sociale – 3. L’orizzonte sociale di riferimento: b) le identità religiose e l’integrazione sociale – 4. La laicità alla prova dell’integrazione sociale – 5. La laicità tra pluralismo religioso e pluralismo culturale – 6. L’integrazione sociale, e le ambigue conseguenze del principio di laicità.
description: Stato, Chiese e pluralismo confessionale, 2016: 12 settembre
title: Using Statistical Classification Algorithms to Decode Covert Speech States with Functional Magnetic Resonance Imaging
Creators: name: McCorry, Devin M.
Publisher: name: George Mason University
Year: 2010
Subjects: subject: Covert speech
subject: Multi-voxel pattern analysis
subject: Brain-computer interface
subject: Support vector machine
subject: FMRI

description: An effective covert speech brain-computer interface (BCI) would be a system that decodes a subject’s internal speech-related neural activity, translating it into text or synthesized speech. Multiple clinical populations stand to benefit from such a BCI, most notable of which are patients with locked-in syndrome — a disorder marked by nearcomplete motor paralysis, despite relatively unimpaired cognition. Determining which regions of the brain contain speech information that could be decoded in a covert speech BCI is an important and necessary step towards actual BCI implementation. In the present study I investigated whether cortical areas involved in motor speech production and speech perception contain such information. I used functional magnetic resonance imaging (fMRI) to scan subjects (2 males and 3 females, mean age = 23.6) while they completed 6 runs of a speech task, in which they were prompted to speak one of two syllables: /pah/ or /tah/. In one scanning session, subjects spoke these syllables overtly (aloud); in another session, they covertly―spoke the syllables in their mind without moving. Results from two independent tasks — a task involving motor articulation, and a task involving perception of speech — were used to select regions of interest (ROIs) for each subject. These ROIs were used to subset the activation observed during the speech tasks. I then used multi-voxel pattern analysis (MVPA) to train statistical algorithms to classify which of the two syllables was spoken (overtly or covertly)—based solely on the subset of fMRI data during the speech tasks. The MVPA was conducted using regressed parameter estimates of the syllables from each of the 6 runs. Classification accuracy was significantly above chance in both the speech production and speech perception ROIs for both overt and covert speech (p < .05). Accuracy was significantly higher for overt versus covert speech (p < .05), and a nonsignificant trend suggested higher accuracy in the motor ROI than in the perception ROI. These findings are significant in that they indicate that neural patterns of activity during covert and overt speech may be similar enough to apply overt speech models to methods of decoding inner speech. Importantly, speech motor and perception regions may encode sufficient detail about a person’s internal speech states to decode in a future implementation of a covert speech BCI. Furthermore, the results of this study demonstrate the utility in using MVPA to map out regions to use in future BCIs based on decoding cognitive states.
Exploring the Relationship between Polymer Surface Chemistry and Bacterial Attachment Using ToF-SIMS and Self-Organizing maps
Creators: name: Wong, See Yoong
name: Hook, Andrew
name: Gardner, Wil
name: Chang, Chienyi
name: Mei, Ying
name: Davies, Martyn
name: Williams, Paul
name: Alexander, Morgan
name: Ballabio, Davide
name: Muir, Ben
name: Winkler, Dave
name: Pigram, Paul
Publisher: name: La Trobe
Year: 2023

description: No description supplied
Studiare Foscolo. Stato dell'arte nella critica foscoliana (con una recensione a "Foscolo e i commentatori danteschi")
Creators: name: Ravera, Giulia
Publisher: name: Prassi Ecdotiche della Modernità Letteraria
Year: 2016

description: (in attesa di caricamento del contributo)
description: Prassi Ecdotiche della Modernità Letteraria, N. 1 (2016)
La voce delle postille "mute". I notabilia manzoniani alle commedie di Giovan Maria Cecchi
Creators: name: Ghirardi, Sabina
Publisher: name: Prassi Ecdotiche della Modernità Letteraria
Year: 2016
Subjects: postille; Alessandro Manzoni; Manzoni; notabilia; Giovan Maria Cecchi; Cecchi

description: (in attesa di caricamento del contributo)
description: Prassi Ecdotiche della Modernità Letteraria, N. 1 (2016)
The Contribution of Visual and Auditory Working Memory and Non-Verbal IQ to Motor Multisensory Processing in Elementary School Children
Creators: name: Alhamdan, Areej
name: Murphy, Melanie
name: Pickering, Hayley
name: Crewther, Sheila
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 3209
subject: Neurosciences
subject: FOS: Clinical medicine
classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5201
subject: Applied and developmental psychology
classificationCode: 5202
subject: Biological psychology
classificationCode: 5204
subject: Cognitive and computational psychology

description: Although cognitive abilities have been shown to facilitate multisensory processing in adults, the development of cognitive abilities such as working memory and intelligence, and their relationship to multisensory motor reaction times (MRTs), has not been well investigated in children. Thus, the aim of the current study was to explore the contribution of age-related cognitive abilities in elementary school-age children (n = 75) aged 5–10 years, to multisensory MRTs in response to auditory, visual, and audiovisual stimuli, and a visuomotor eye–hand co-ordination processing task. Cognitive performance was measured on classical working memory tasks such as forward and backward visual and auditory digit spans, and the Raven’s Coloured Progressive Matrices (RCPM test of nonverbal intelligence). Bayesian Analysis revealed decisive evidence for age-group differences across grades on visual digit span tasks and RCPM scores but not on auditory digit span tasks. The results also showed decisive evidence for the relationship between performance on more complex visually based tasks, such as difficult items of the RCPM and visual digit span, and multisensory MRT tasks. Bayesian regression analysis demonstrated that visual WM digit span tasks together with nonverbal IQ were the strongest unique predictors of multisensory processing. This suggests that the capacity of visual memory rather than auditory processing abilities becomes the most important cognitive predictor of multisensory MRTs, and potentially contributes to the expected age-related increase in cognitive abilities and multisensory motor processing.
«It cannot be considered a finished work». "Le donne di Messina" di Elio Vittorini
Creators: name: Mastropaolo, Maria Rita
Publisher: name: Prassi Ecdotiche della Modernità Letteraria
Year: 2016
Subjects: riscritture; Elio Vittorini; Vittorini; Le donne di Messina; carte autografe; varianti; archivi

description: (in attesa di caricamento del contributo)
description: Prassi Ecdotiche della Modernità Letteraria, N. 1 (2016)
Il testo letterario tra volontà dell'autore e volontà dell'editore
Creators: name: Cadioli, Alberto
Publisher: name: Prassi Ecdotiche della Modernità Letteraria
Year: 2016
Subjects: volontà d'autore; editore; editoria; varianti; correzioni; riscritture; editing; redazione

description: (in attesa del caricamento del contributo)
description: Prassi Ecdotiche della Modernità Letteraria, N. 1 (2016)
Additional file 1 of Peri- and postoperative morbidity and mortality in older patients with non-small cell lung cancer: a matched-pair study
Creators: name: Safi, Seyer
name: Gysan, Maximilian Robert
name: Weber, Dorothea
name: Behnisch, Rouven
name: Muley, Thomas
name: Allgäuer, Michael
name: Winter, Hauke
name: Hoffmann, Hans
name: Eichhorn, Martin
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
From Knowledge Curator to Knowledge Creator: Academic Libraries and Open Access Textbook Publishing
Creators: name: Salisbury, Fiona
name: Julien, Brianna
name: Loch, Birgit
name: Chang, Steven
name: Lexis, Louise
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 461007
subject: Open access

description: Introduction: Access to learning resources is not always affordable or equitable for students in higher educa-tion, and high-cost resources, which are commonly prescribed in course reading lists, create barriers for learn-ing. Incorporating open access textbooks in reading lists responds to these issues. Academic librarians’ expertise in curating, organizing, and disseminating knowledge coupled with a long-held passion for open access means that they are well positioned to drive partnerships with academic colleagues that prioritize the use and creation of open educational resources resulting in resources that are accessible, high quality, flexible, and appropriate to support learning in all modes (online, blended, face-to-face).
Description of program/service: At La Trobe University Library, a commitment to openness provided a start-ing point for rethinking the role of the library as a publisher of open educational resources. The La Trobe eBureau is an Australian academic library publishing initiative designed to produce high-quality, peer-reviewed open textbooks by La Trobe University authors for La Trobe University courses. Situating the library as an open textbook publisher in partnership with academics improves the affordability of course resources, the student online learning experience, and the visibility of academic outputs and, importantly, has impact and value across higher education institutions.
Next steps: This article shares reflections and challenges from the perspective of eBureau authors and library staff. The Library will continue to build on the success of eBureau collaborations and look more broadly to enact the future role of academic libraries in sustainable open textbook publishing within La Trobe University and across the higher education sector.
Supplementary document for Optical and electrical properties characterisation of photovoltaic spatial-light modulators - 6417088.pdf
Creators: name: Brouckaert, Nicolas
name: Bankova, Denitsa
name: D'Alessandro, Giampaolo
name: Kaczmarek, Malgosia
name: Heiser, Thomas
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Optical Physics not elsewhere classified

description: Supplemental information for "Optical and electrical properties characterisation of photovoltaic spatial-light modulators"