cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phenolic compounds from the stems of Flickingeria fimbriata
Creators: name: Wu, Ya-Ping
name: Liu, Wen-Jian
name: Zhong, Wen-Jun
name: Chen, Yue-Juan
name: Chen, Dan-Na
name: He, Feng
name: Jiang, Lin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biochemistry
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Chemical investigation of Flickingeria fimbriata (Bl.) Hawkes (Orchidaceae) resulted in the isolation and identification of one new dihydrophenanthrene, 1,2,5,6,7-pentamethoxy-9,10-dihydrophenanthrene (1), together with seven known dihydrophenanthrenes, erianthridin (2), coelonin (3), 4-methoxy-9,10-dihydrophenanthrene-1,2,7-triol (4), lusianthridin (5), ephemeranthol A (6), flavanthridin (7) and hircinol (8), four known phenanthrenes, epheranthol B (9), nudol (10), denthyrsinin (11) and confusarin (12), and one known bibenzyl, batatasin III (13). The structure of the new compound was elucidated by spectroscopic analysis (HRMS, 1D and 2D NMR). All the compounds were isolated from F. fimbriata for the first time except for compounds 5 and 12, and compounds 1, 3, 4, 8, 10, 11 and 13 were obtained from this genus for the first time. Compounds 1–4 showed moderate cytotoxic activity against HepG2 cells.
Supplementary document for Spatiotemporal dissipation dynamics: route to high beam quality and high peak power spatiotemporal mode-locked fiber lasers - 7237824.pdf
Creators: name: Fu, Guohao
name: Li, Yuhang
name: Xiao, Qirong
name: Li, Dan
name: Gong, Mali
name: Liu, Qiang
name: Wabnitz, Stefan
name: Yan, Ping
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Complex Physical Systems
Lasers and Quantum Electronics
Applied Physics
Nonlinear Optics and Spectroscopy

description: The supplement presents simulation methods, simulation results, and some experimental results.
Kitamycin C, a new antimycin-type antibiotic from Streptomyces antibioticus strain 200-09
Creators: name: Wang, Fan
name: Fu, Shu-Na
name: Bao, Yi-Xuan
name: Yang, Yu
name: Shen, Hui-Fang
name: Lin, Bi-Run
name: Zhou, Guang-Xiong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: An actinomycete strain 200-09, isolated from a soil sample collected from the coast of Hawaii, USA, was identified as Streptomyces antibioticus on the basis of its morphological, physiological and biochemical characteristics as well as 16S rDNA analysis. A new antimycin-type antibiotic, kitamycin C (1), together with kitamycin A (2), kitamycin B (3), urauchmycin B (4), deisovaleryblastomycin (5) was isolated from a cultured broth of strain 200-09. The structure of the new compound was determined by spectroscopic data, including HR-ESI-MS and NMR. All the compounds exhibited antifungal activities against Candida albicans with MIC of about 25.0 μg mL−1.
Software
Creators: name: Ibaviosa, Carlos
name: Searston, Rachel A.
Publisher: name: OSF Registries
Year: 2019

description: This component contains the full set of 30 pre-generated unique participant sequences (.txt) that are read into the open source experiment presentation software we developed for this project. The LiveCode source file (version 9.0.4) for presenting the sequences and materials to participants and collecting their responses is included in the .zip file, along with the instructional video participants view before completing the task. LiveCode’s Community Edition, is a free open source object-oriented, cross-platform, natural language rapid development environment that can be used for programming local (LiveCode) and web-based (HTML5) experiments. LiveCode is based on the Transcript programming language (a high-level xTalk scripting language like HyperCard’s HyperTalk), and is a great stepping stone to learning Javascript and Python. It is fit for developing experiments that require fine-grained control, complex sequencing, and heavy back-end processing. You can download LiveCode for PC, Linux or Mac at: https://downloads.livecode.com/livecode. You can run these experiments on your own computer by installing the appropriate version of LiveCode Community, and downloading the zip file. Note, however, that the “prints” folder is empty for Experiment 2 (the fingerprint task), which you’ll need for the experiment to run properly. The fingerprint images we used in this project were sourced from the FIB-R database and we do not have permission to share them in a public repository. If you’d like to access the prints we used in this project for research purposes please contact Rachel Searston (rachel.searston@adelaide.edu.au).
Supplementary methods, ESM figures S1-S3 and ESM tables S1-S7 from Hydrodynamic regime determines the feeding success of larval fish through the modulation of strike kinematics
Creators: name: China, Victor
name: Levy, Liraz
name: Liberzon, Alex
name: Elmaliach, Tal
name: Roi Holzman
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: Supplementary methods, ESM figures S1-S3 and ESM tables S1-S7
Procyshyn 2017 GTF2I Oxytocin Electronic Supplementary Materials from The Williams syndrome prosociality gene GTF2I mediates oxytocin reactivity and social anxiety in a healthy population
Creators: name: Procyshyn, Tanya L.
name: Spence, Jason
name: Silven Read
name: Watson, Neil V.
name: Crespi, Bernard J.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Supplementary Tables S1 - S4, Supplementary Figure S1
Antimicrobial activity of saponins produced by two novel endophytic fungi from Panax notoginseng
Creators: name: Jin, Zhaoxia
name: Gao, Lin
name: Zhang, Lin
name: Liu, Tianyi
name: Yu, Fang
name: Zhang, Zongshen
name: Guo, Qiong
name: Wang, Biying
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Endophytes in plants may be co-producer of the bioactive compounds of their hosts. We conducted a study to bioprospect for saponin-producing endophytic fungi from Panax notoginseng and evaluate the antimicrobial activity of saponins. Two novel fungal endophytes, Fusarium sp. PN8 and Aspergillus sp. PN17, were isolated from traditional Chinese medicinal herb P. notoginseng. After eight days of fermentation, the total saponins produced in the culture broth of PN8 and PN17 were 1.061 and 0.583 mg mL−1, respectively. The saponin extracts exhibited moderate to high (inhibition zone diameter 15.7–28.4 mm, MIC 1.6–12.5 mg mL−1) antimicrobial activity against pathogens tested. Further analysis showed that triterpenoid saponins produced by Fusarium PN8 were Rb1, Rd and 20(S)-Rg3, while Aspergillus PN17 had the ability to synthesise ginsenoside Re, Rd and 20(S)-Rg3. The isolated endophytes may be used as potential sources for microbial production of plant secondary metabolites and for antimicrobial agents.
Supplementary analyses of Experiment 3 from Modulation of the composite face effect by unintended emotion cues
Creators: name: Gray, Katie L. H.
name: Murphy, Jennifer
name: Marsh, Jade E.
name: Cook, Richard
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 179999 Psychology and Cognitive Sciences not elsewhere classified
subject: FOS: Psychology

description: Analyses based on the ‘original design’ trials (i.e. only the trials in which the distractor halves differ).
Two new similar alkaloids from Portulaca oleracea L.
Creators: name: Li, Cuiyu
name: Ying, Zheming
name: Gao, Mingzhe
name: Wei, Wenjuan
name: Hao, Dong
name: Xu, Liang
name: Tao, Xiaojun
name: Zhang, Wenjie
name: Ying, Xixiang
name: Liu, Jing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Two novel alkaloids named oleraciamide A (1) and oleraciamide B (2) were isolated from Portulaca oleracea L., and spectroscopic methods including 1D and 2D nuclear magnetic resonance and high-resolution electrospray ionisation quadrupole-time of flight mass spectrometer spectrometry techniques are employed to determine their structures. Oleraciamide A (1) was evaluated no cytotoxicity at concentrations up to 80 μM over 72 h against human adipose-derived stem cells (hADSCs) by CCK-8 method.
Supplementary notes from Optimal strategies for throwing accurately
Creators: name: M. Venkadesan
name: L. Mahadevan
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Mechanical Engineering
subject: FOS: Mechanical engineering
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: Detailed derivations and extensions of the mathematical analyses presented in the paper.
Supplementary material from Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique
Creators: name: Yunusova, Anastasia M.
name: Fishman, Veniamin S.
name: Vasiliev, Gennady V.
name: Battulin, Nariman R.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Cell Biology
subject: Developmental Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Supplementary figures for all experiments presented in “Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique”
Supplemental Material from Candidate genes mediating magnetoreception in rainbow trout (Oncorhynchus mykiss)
Creators: name: Fitak, Robert R.
name: Wheeler, Benjamin R.
name: Ernst, David A.
name: Lohmann, Kenneth J.
name: Johnsen, Sönke
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biophysics
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Additional methods, tables, figures, and references
Evaluating Korean rice genotypes and landraces for octacosanol contents and antioxidant activity
Creators: name: Cho, Yang-Hee
name: Farhoudi, Rozbeh
name: Farooq, Muhammad
name: Lee, Dong-Jin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Plant Biology

description: Increase in the average life span and interest in correlation between food and human health have led to researches to find and utilise the functional materials in rice. Octacosanol in rice grain is well known for its potential benefit. This study was conducted to evaluate the Korean rice (Oryza sativa L.) genotypes and landraces for octacosanol contents and antioxidant activity. Octacosanol contents in 223 cultivars of Korean rice ranged from 0.78 to 6.06 mg 100 g−1. Thirteen genotypes and landraces had high contents of octacosanol (4 mg 100 g−1). The antioxidant activity in Korean rice ranged from 12 to 96%. Among the tested genotypes and landraces, red-coloured rice accessions had more than 90% antioxidant activity. Genotypes with high level of octacosanol and antioxidant activity may be useful for rice breeders to develop functional varieties and food processing as nutraceutical materials.
A new sucrosephenylpropanoid ester from Polygonum pubescens Blume
Creators: name: Liu, Qiang
name: Li, Bin
name: Zhao, Jianping
name: Khan, Shabana I.
name: Liu, Wen-Bin
name: Zeng, Ting
name: Peng, Cai-Yun
name: Cai, Xiong
name: Peng, Qinghua
name: Huang, Huiyong
name: Khan, Ikhlas A.
name: Wang, Wei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: The present study investigated the chemical constituents of aerial part of Polygonum pubescens Blume. Twenty-two compounds 1–22 were obtained from petroleum ether and ethyl acetate extracts of aerial part of P. pubescens, including a new phenylpropanoide esters 1 and 21 known compounds. The structures were determined on the basis of spectroscopic and chemical methods. Sixteen compounds were assessed for their cytotoxic and anti-inflammatory activities. Several compounds showed effects on different targets.
Phenylpropanoids from the fruits of Nicandra physaloides and their anti-inflammatory activities
Creators: name: Yang, Bing You
name: Liu, Yan
name: Jiang, Hai Bing
name: Xu, Zhen Peng
name: Guo, Rui
name: Wang, Rui
name: Li, Xiao Mao
name: Kuang, Hai Xue
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Twenty-one phenylpropanoids, including 1 new (1) and 20 known phenylpropanoids (2–21), were isolated and identified from the fruits of Nicandra physaloides. The structures of these compounds were established by 1D and 2D NMR spectra referring to the literatures, together with mass spectrometry. It was found that the isolated compounds, except for 7, 18 and 19, showed the different levels of inhibitions on NO production by LPS-induced RAW 264.7 cells at IC50 values from 27.0 to 97.3 μM.
Structure analysis of adiabatic film cooling effectiveness in the near field of a single inclined jet: Measurement using fast-response pressure-sensitive paint
Creators: name: Khojasteh, Ali Rahimi
name: Wang, Shao Fei
name: Peng, Di
name: Savas Yavuzkurt
name: Yingzheng Liu
Publisher: name: figshare
Year: 2017
Subjects: subject: Mechanical Engineering
subject: FOS: Mechanical engineering
subject: 91508 Turbulent Flows
subject: FOS: Other engineering and technologies

description: In the present study, the film cooling effectiveness in the near field (x/D 4). The blowing ratios M = 0.5 and 1.0 were used. The coolant fluid was nitrogen and the air was the mainstream fluid, and both were kept at the same temperature. A fast-PSP measurement technique was used to determine the variations of the film cooling effectiveness with time. The contours of the time-averaged film cooling effectiveness demonstrated that the coolant spread on the surface throughout the near-hole region at M = 0.5, while at M = 1.0, the coolant jet detached from the surface immediately behind the hole and reattached downstream around 1.5 D behind the hole’s trailing edge. The spatial distribution of the film cooling effectiveness fluctuations and its cross-correlation pattern convincingly reflected the substantial influence of the energetic unsteady flow structures in the jet and cross-flow interaction. Subsequently, the Proper Orthogonal Decomposition (POD) method was used to identify the coherent parts of the film cooling effectiveness, which are regarded as the signatures of the convective large-scale vortical structures above the wall. At M=0.5, the near-hole region was subjected to the dominant influence of the counter-rotating vortex pair (CRVP), characterized by the first two POD modes, which contained up to 40% of the fluctuation energy. Two signatures of large-scale symmetric structures were identified with similar energy levels. The second two POD modes corresponding to the horseshoe vortex near the leading edge of the hole were identified and contained around 10% of the fluctuation energy. Phase-dependent variations of the large-scale convective signatures in relation to the quasi-periodic CRVP and horseshoe vortex were separately detected. At M = 1.0, the signatures of the CRVP and the horseshoe vortex were also seen in the POD modes, though they were relatively difficult to distinguish.
The effects of sEH inhibitor on depression-like behavior and neurogenesis in male mice
Creators: name: Qiong, Wu
Publisher: name: figshare
Year: 2017
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: We found that acute administration of sEHI TPPU decreases immobility time in the forced swimming test and reduces latency to feed in the novelty suppressed-feeding test in adult male mice. Intraperitoneal administration of TPPU for 7 days also increased interaction time of socially defeated mice in the social defeat test. Hippocampal BDNF expression and cell proliferation in the dentate gyrus increased 6 and 24 h after TPPU treatment, respectively. Improvement in antidepressant behavior and cell proliferation were inhibited by BDNF-trkB antagonist K252a, which suggests that anti-depressant effects of sEHI may be involved in BDNF signaling. 
Atomistic simulations on interwall sliding behaviour of double-walled carbon nanotube: effects of structural defects
Creators: name: Xuebo Yuan
name: Youshan Wang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy

description: In this study, we investigated the interwall sliding behaviours of double-wall carbon nanotubes (DWCNTs) using molecular dynamics (MD) simulations, focusing on the effects of different structural defects including the vacancy, adsorbed atom (Adatom) and Stone-Wales (SW) defects. The simulation results showed that structural defects, especially the Adatom ones, caused large fluctuations and decreased the overall pull-out force. Stick-slip motions were observed in the interwall sliding processes of DWCNTs containing multiple structural defects. Among three types of structural defects, the Adatom defects most significantly weaken the interwall load transferring capability and degrade the interface shear strength (IFSS). This work provides useful information for promoting DWCNTs’ applications in Micro/Nano Electro-Mechanical Systems (M/NEMS).
Biocompatible hyperbranched polyester magnetic nanocarrier for stimuli-responsive drug release
Creators: name: Zhao, Chili
name: Han, Qiaorong
name: Qin, Hong
name: Yan, Hong
name: Qian, Zhilei
name: Ma, Zhenye
name: Zhang, Xia
name: Li, Xinghui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: A novel biocompatible magnetic nanocomposite drug carrier was developed by first chemically modifying a hyperbranched polyester (HBPE) with dodecenyl succinic anhydride (DDSA) functional groups to produce HBPE-DDSA. The magnetic nanocomposite Fe3O4/HBPE-DDSA was then synthesized by dispersing superparamagnetic iron oxide (Fe3O4) nanoparticles within HBPE-DDSA. The structure and magnetic properties of the nanocomposite were characterized by 1H NMR, MALDI-MS, XRD, FTIR, TEM, and SQUID analyses. Isoniazid (INH) was selected as a model antituberculosis drug to investigate the in vitro drug release properties of Fe3O4/HBPE-DDSA/INH. The cytotoxicity of the magnetic nanocomposites was assessed by CCK-8 assay. The results indicated that Fe3O4/HBPE-DDSA is a promising potential drug carrier for a magnetic-targeted drug delivery system.
A simulation optimisation approach for real-time scheduling in an open shop environment using a composite dispatching rule
Creators: name: Nasiri, Mohammad Mahdi
name: Yazdanparast, Reza
name: Fariborz Jolai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: In the last decades, many researchers have studied open shop scheduling (OSS) problem by considering deterministic parameters using mathematical modelling, heuristics and meta-heuristics. However, it is important to study the problem as close as possible to real world conditions which consists of uncertainty and stochastic parameters. In this study, dispatching rules, as accepted tools for real-time scheduling, are applied for optimising the OSS problem. Since none of conventional dispatching rules performs well for all performance measures, a simulation-based real-time scheduling composite dispatching rule is developed. For this purpose, a multi response optimisation approach based on computer simulation for scheduling a non-preemptive open shop with stochastic ready times is presented in order to minimise the mean waiting time of jobs. The presented approach composed of design of experiments, discrete event simulation, multi-layer perceptron artificial neural network, radial basis function and data envelopment analysis to determine the most efficient dispatching rule for each machine.
Assigning licenced technicians to maintenance tasks at aircraft maintenance base: a bi-objective approach and a Chinese airline application
Creators: name: Chen, Gang
name: He, Wen
name: Leung, Lawrence C.
name: Lan, Tian
name: Han, Yingying
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Assigning technicians to maintenance tasks at an aircraft maintenance base is challenging and needs to consider technician licences, fairness and such operational constraints as hangar capacity and work shifts. We formulate the problem as a bi-objective optimisation model, which minimises total cost while simultaneously achieving fairness in workload allocation among different technicians. A tabu-based heuristic algorithm is developed to obtain Pareto efficient solutions. The algorithm is shown to be effective through comparison with CPLEX. A case study from a major Chinese airline demonstrates that our optimisation-based approach is applicable and beneficial to the practice. Managerial issues on maintenance workforce management are examined as well. The results show that training technicians and upgrading their licences may not be better off, and increasing the number of technicians has both favourable and unfavourable effects.
Noninvasive hemoglobin measurement based on optimizing Dynamic Spectrum method
Creators: name: Li, Gang
name: Xu, Sijia
name: Zhou, Mei
name: Zhang, Qirui
name: Lin, Ling
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Plant Biology

description: An optimizing Dynamic Spectrum method based on short-time Fourier transform for noninvasive hemoglobin measurement was proposed. A total of 187 volunteers’ spectral data and blood samples were prepared for the calibration (167 samples) and prediction (20 samples) sets. Data processing with optimizing dynamic spectrum method was set as experimental group, while control group was with classical method based on fast Fourier transform. The model for hemoglobin prediction was established with partial least square regression. In the experimental group, the average prediction correlation coefficient was 0.8399, while that of the control group was 0.6686. The results demonstrate that the optimizing method has a good accuracy improvement for noninvasive hemoglobin measurement. The optimizing dynamic spectrum method combining statistical characteristics analysis as a modified analytical method has a promising application prospect of application in noninvasive blood component measurement field.
Noninvasive Hemoglobin Measurement Based on Optimizing Dynamic Spectrum Method
Creators: name: Li, Gang
name: Xu, Sijia
name: Zhou, Mei
name: Zhang, Qirui
name: Lin, Ling
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Plant Biology

description: An optimizing Dynamic Spectrum method based on short-time Fourier transform for noninvasive hemoglobin measurement was proposed. A total of 187 volunteers’ spectral data and blood samples were prepared for the calibration (167 samples) and prediction (20 samples) sets. Data processing with optimizing dynamic spectrum method was set as experimental group, while control group was with classical method based on fast Fourier transform. The model for hemoglobin prediction was established with partial least square regression. In the experimental group, the average prediction correlation coefficient was 0.8399, while that of the control group was 0.6686. The results demonstrate that the optimizing method has a good accuracy improvement for noninvasive hemoglobin measurement. The optimizing dynamic spectrum method combining statistical characteristics analysis as a modified analytical method has a promising application prospect of application in noninvasive blood component measurement field.
eFTI Regulation and its effects on the Greek Market
Creators: name: Kanellopoulos, Giannis
Publisher: name: Zenodo
Year: 2022

description: Supply Chain Day was established by the German logistics organization BVL International as a day of information and promotion of logistics and supply chain through the organization of events, speeches, presentations and guided tours of business premises. Companies and organizations open their gates giving the public the opportunity to be informed about the supply chain industry and the wide variety of activities under the logistics. Supply Chain Day was celebrated for the first time on April 16, 2008 in Germany and Austria and since then it has been established in many European countries with the motto “Logistics paves the way”. ILME as a member of the European Logistics Association (ELA) has been honouring this day uninterruptedly since 2015. For the year of 2022, ILME invited the interested stakeholders to the international online conference, 5th International Logistics Forum & Supply Chain Day, organized by ILME, on 5 April at 16:00-20:00. With the topic “The emerging era of Logistics | Collaboration, Technology, Training” attendees and participants discussed all the burning issues that concern our industry today and in the future. Mr. Giannis Kanellopoulos from NTUA, delivered a presentation entitled: ‘eFTI Regulation and its effects on the Greek Market’.
Fig.1-modified.tif
Creators: name: Qiong, Wu
Publisher: name: figshare
Year: 2017
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: We found that acute administration of sEHI TPPU decreases immobility time in the forced swimming test and reduces latency to feed in the novelty suppressed-feeding test in adult male mice. Intraperitoneal administration of TPPU for 7 days also increased interaction time of socially defeated mice in the social defeat test. Hippocampal BDNF expression and cell proliferation in the dentate gyrus increased 6 and 24 h after TPPU treatment, respectively. Improvement in antidepressant behavior and cell proliferation were inhibited by BDNF-trkB antagonist K252a, which suggests that anti-depressant effects of sEHI may be involved in BDNF signaling. 
Transport properties of valsartan, sacubitril and its active metabolite (LBQ657) as determinants of disposition
Creators: name: Hanna, Imad
name: Alexander, Natalya
name: Crouthamel, Matthew H.
name: Davis, John
name: Natrillo, Adrienne
name: Tran, Phi
name: Vapurcuyan, Arpine
name: Zhu, Bing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: 1. The potential for drug–drug interactions of LCZ696 (a novel, crystalline complex comprising sacubitril and valsartan) was investigated in vitro. 2. Sacubitril was shown to be a highly permeable P-glycoprotein (P-gp) substrate and was hydrolyzed to the active anionic metabolite LBQ657 by human carboxylesterase 1 (CES1b and 1c). The multidrug resistance-associated protein 2 (MRP2) was shown to be capable of LBQ657 and valsartan transport that contributes to the elimination of either compound. 3. LBQ657 and valsartan were transported by OAT1, OAT3, OATP1B1 and OATP1B3, whereas no OAT- or OATP-mediated sacubitril transport was observed. 4. The contribution of OATP1B3 to valsartan transport (73%) was appreciably higher than that by OATP1B1 (27%), Alternatively, OATP1B1 contribution to the hepatic uptake of LBQ657 (∼70%) was higher than that by OATP1B3 (∼30%). 5. None of the compounds inhibited OCT1/OCT2, MATE1/MATE2-K, P-gp, or BCRP. Sacubitril and LBQ657 inhibited OAT3 but not OAT1, and valsartan inhibited the activity of both OAT1 and OAT3. Sacubitril and valsartan inhibited OATP1B1 and OATP1B3, whereas LBQ657 weakly inhibited OATP1B1 but not OATP1B3. 6. Drug interactions due to the inhibition of transporters are unlikely due to the redundancy of the available transport pathways (LBQ657: OATP1B1/OAT1/3 and valsartan: OATP1B3/OAT1/3) and the low therapeutic concentration of the LCZ696 analytes.
Immune modulation properties of herbal plant leaves: Phyllanthus niruri aqueous extract on immune cells of tuberculosis patient - in vitro study
Creators: name: Putri, Denise Utami
name: Rintiswati, Ning
name: Marsetyawan HNE Soesatyo
name: Haryana, Sofia Mubarika
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Disease progression in Tuberculosis (TB) is dependent on host’s immune system. Phyllanthus niruri, a traditional herb, has long been used to boost immune system in Indonesian society. This study aimed to observe the potential role of P. niruri in inducing immune cells activity in TB patients by in vitro approach. Peripheral blood mononuclear cells (PBMCs) and macrophages were collected from active pulmonary TB patients. After stimulation with graded doses of P. niruri aqueous extract, cell proliferation, phagocytic activity and nitric oxide (NO) release were analysed. P. niruri aqueous extract induced proliferation of PBMCs, increased NO release, and improved macrophages phagocytic activity. These effects were observed in a dose-dependent manner. This may lead to further research for the potential role of P. niruri as immunomodulatory adjuvant therapy for TB patients.
Diterpenoids with thioredoxin reductase inhibitory activities from Jatropha multifida
Creators: name: Zhu, Jian-Yong
name: Zhang, Chun-Yang
name: Dai, Jing-Jing
name: Rahman, Khalid
name: Zhang, Hong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Chemical investigation of the Jatropha multifida has led to the isolation of nine diterpenoids (1–9), including a new jatromulone A, four podocarpane diterpenoids (2–5), two lathyrane-type diterpenoids (6 and 7) and two dinorditerpenoids (8 and 9). Their structures were elucidated by spectroscopic analysis, and the absolute configurations of 1 were determined by CD analysis. All of the diterpenoids were screened for inhibitory activity against thioredoxin reductase (TrxR), which is a potential target for cancer chemotherapy with redox balance and antioxidant functions. Compounds 6 and 7 exhibited stronger activity (IC50: 23.4 and 10.6 μM, respectively) than the positive control, curcumin (IC50 = 25.0 μM). Compounds 2–9 were isolated from J. multifida for the first time.
Experimental and computational approaches to reveal the potential of Ficus deltoidea leaves extract as α-amylase inhibitor
Creators: name: Amirul Ridzuan Abu Bakar
name: Thamilvaani Manaharan
name: Merican, Amir Feisal
name: Saharuddin Bin Mohamad
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Ficus deltoidea leaves extract are known to have good therapeutic properties such as antioxidant, anti-inflammatory and anti-diabetic. We showed that 50% ethanol-water extract of F. deltoidea leaves and its pungent compounds vitexin and isovitexin exhibited significant (p 50 (vitexin: 4.6 μM [0.02 μg/mL]; isovitexin: 0.06 μg/mL [13.8 μM] and DPPH scavenging with IC50 (vitexin: 92.5 μM [0.4 μg/mL]; isovitexin: 0.5 μg/mL [115.4 μM]). Additionally, molecular docking analysis confirmed that vitexin has a higher binding affinity (-7.54 kcal/mol) towards α-amylase compared to isovitexin (−5.61 kcal/mol). On the other hand, the molecular dynamics findings showed that vitexin-α-amylase complex is more stable during the simulation of 20 ns when compared to the isovitexin-α-amylase complex. Our results suggest that vitexin is more potent and stable against α-amylase enzyme, thus it could develop as a therapeutic drug for the treatment of diabetes.
Geological controls and methane sorption capacity of marine shales of the Fuling shale gas field in the eastern Sichuan Basin, China
Creators: name: Zhang, Xiaoming
name: Shi, Wanzhong
name: Hu, Qinhong
name: Zhang, Shiwan
name: Hu, Haiyan
name: Wang, Xiaolong
name: Xu, Zhuang
Publisher: name: Geological Society of London
Year: 2017

description: Additional description of experimental data
Bioactive triterpenoids from the leaves of Eriobotrya japonica as the natural PDE4 inhibitors
Creators: name: Tan, Bing-Xin
name: Yang, Lu
name: Huang, Yi-You
name: Chen, Yun-Yun
name: Peng, Guang-Tian
name: Yu, Si
name: Wu, Yi-Nuo
name: Luo, Hai-Bin
name: He, Xi-Xin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology

description: The ethanolic extract of the leaves of Eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4D (PDE4D), which is a therapeutic target of inflammatory disease. Subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl corosolate (2), ursolic acid (3), oleanolic acid (4), methyl maslinate (5), α-amyin (6), 3β,19α,23-trihydroxy-urs-12-ene (7) and uvaol (8). The structure of compound 1 was established as 3β-hydroxyl-21β-acetoxyl-urs-12-en-28-carboxylate on the basis of interpretation of its 1D and 2D NMR and HR-ESI-MS spectroscopic data. The bioassay results verified compounds 2, 3 and 8 inhibited PDE4D2 effectively with the IC50 values of 3.06, 2.18 and 5.17 μM, respectively, which may provide a novel mechanism for the anti-inflammatory activity of the leaves of E. japonica.
PaNOSC position paper on the EOSC
Creators: name: Goetz, Andy
Publisher: name: Zenodo
Year: 2020
Subjects: EOSC
European Open Science Cloud
FAIR principles
data stewardship
Open data
PaNOSC

description: PaNOSC position paper on the EOSC endorsed by the PaNOSC Executive and Management Board. Table of content: Introduction PaNOSC objectives EOSC Minimum Viable Ecosystem PaNOSC provides Feedback to the EOSC Executive Board Example data References
Fabrication of mechanically robust superhydrophobic aluminum surface by acid etching and stearic acid modification
Creators: name: Wei, Zhibo
name: Jiang, Deyi
name: Chen, Jie
name: Ren, Song
name: Li, Lin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences

description: The aluminium surface with multi-scale structure has been fabricated via a facile and rapid solution-phase etching method by HCl/H2O2 etchants. After modification with stearic acid solution, the wettability of the etched aluminum surface turns into superhydrophobicity with an optimal water contact angle of 160° ± 2° and a sliding angle of 4° ± 1°. The processing conditions, such as the etching time, modifier types and the concentration of H2O2 are investigated to determine their effects on the surface morphology and wettability. As a result, the obtained sample shows excellent anti-adhesion property and bouncing phenomenon of water droplet. It can withstand mechanical abrasion for at least 100 cm under 12.3 kPa, or hydrostatic pressure under 24 ± 1 kPa without losing its superhydrophobicity, suggesting superior mechanical durability. Moreover, the surface also remains superhydrophobicity even after contacting corrosive liquids or long-term exposure in air over 100 days. Such a mechanically durable superhydrophobic aluminum surface can provide a promising practical application in various fields.
Phenolic content and antioxidant properties of seeds from different grape cultivars grown in Iran
Creators: name: Vasigheh Sadat Mirbagheri
name: Alizadeh, Ebrahim
name: Elahi, Mostafa Yousef
name: Bahabadi, Sedigheh Esmaeilzadeh
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: Plant Biology

description: This study investigated the antioxidant activity and phenolic composition of seed extracts from three grape cultivars grown in Iran. Folin Ciocalteu method was used for the determination of the total phenolic contents and GC–MS was used for the analysis of phenolic compositions. 1,1-diphenyl-2-picrylhydrazyl (DPPH) method was used to evaluate the antioxidant activity. The highest and the lowest total phenolic contents of seed extract were found in the black and green grape, respectively. The content of individual phenols such as Frulic acid, Gentistic acid, Syringic acid, (+) Catechin, Chlorogenic acid and (−)- Epicatchin gallate was cultivars dependent. The antioxidant activity of the seed extracts ranged from 34.03% (Green) to 53.63% (Black). Generally, the Black grape seed extract with the total phenolic content (3 ± 0.01 mg tannic acid/g DM), DPPH (53.63 ± 0.34%), IC50 and AEAC (7.41 and 16.92 mg/mL) showed the highest level of total antioxidant capacity.
Provincial-level data sources for H5N1 poultry outbreaks, human infections, socioeconomic and environmental risk factors in China (2004-2012) from Conservation, development and the management of infectious disease: avian influenza in China, 2004–2012
Creators: name: Wu, Tong
name: Perrings, Charles
Publisher: name: The Royal Society
Year: 2017

description: There is growing evidence that wildlife conservation measures have mixed effects on the emergence and spread of zoonotic disease. Wildlife conservation has been found to have both positive (dilution) and negative (contagion) effects. In the case of avian influenza H5N1 in China, the focus has been on negative effects. Lakes and wetlands attracting migrating waterfowl have been argued to be disease hotspots. We consider the implications of waterfowl conservation for H5N1 infections in both poultry and humans between 2004 and 2012. We model both environmental and economic risk factors. Environmental risk factors comprise the conditions that structure interaction between wild and domesticated birds. Economic risk factors comprise the cost of disease, biosecurity measures and disease risk mitigation. We find that H5N1 outbreaks in poultry populations are indeed sensitive to the existence of wild-domesticated bird mixing zones, but not in the way we would expect from the literature. We find that risk is decreasing in protected migratory bird habitat. Since the number of human cases is increasing in the number of poultry outbreaks, as expected, the implication is that the protection of wetlands important for migratory birds offers unexpected human health benefits.This article is part of the themed issue ‘Conservation, biodiversity and infectious disease: scientific evidence and policy implications’.
A formulation of neem cake seeded with Bacillus sp. provides control over tomato Fusarium crown and root rot
Creators: name: Lin, Fei
name: Liu, Niu
name: Lai, Duo
name: Kang, Xiang Hui
name: Pang, Neng Wen
name: Jiang, Hong Kai
name: Xu, Han Hong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Fusarium crown and root rot (FCRR) caused by the fungus Fusarium oxysporum f. sp. radicis-lycopersici is a damaging soil-borne disease of tomato. A plant growth rhizobacterium, Bacillus sp. strain HN09 isolated from neem tree rhizosphere soil, was shown to inhibit the growth, germination and development of normal morphology of the FCRR pathogen. A substantial level of disease control was achieved in greenhouse trials by soil supplementation with a preparation of neem cake seeded with HN09. Dry sterilisation of neem cake before fermentation gained comparable disease control effect as those in the unsterilised treatment, whereas moist sterilisation treatment decreased the effect significantly. This bioformulation also led to significantly raised activities in tomato genes encoding pathogenesis-related proteins, hence providing an effective alternative for the control of FCRR, reducing the need for chemical fungicide and fertilisers that impact the environment.
Natural light-micro aerobic condition for PSB wastewater treatment: a flexible, simple, and effective resource recovery wastewater treatment process
Creators: name: Lu, Haifeng
name: Han, Ting
name: Zhang, Guangming
name: Ma, Shanshan
name: Zhang, Yuanhui
name: Li, Baoming
name: Cao, Wei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Photosynthetic bacteria (PSB) have two sets of metabolic pathways. They can degrade pollutants through light metabolic under light-anaerobic or oxygen metabolic pathways under dark-aerobic conditions. Both metabolisms function under natural light-microaerobic condition, which demands less energy input. This work investigated the characteristics of PSB wastewater treatment process under that condition. Results showed that PSB had very strong adaptability to chemical oxygen demand (COD) concentration; with F/M of 5.2–248.5 mg-COD/mg-biomass, the biomass increased three times and COD removal reached above 91.5%. PSB had both advantages of oxygen metabolism in COD removal and light metabolism in resource recovery under natural light-microaerobic condition. For pollutants’ degradation, COD, total organic carbon, nitrogen, and phosphorus removal reached 96.2%, 91.0%, 70.5%, and 92.7%, respectively. For resource recovery, 74.2% of C in wastewater was transformed into biomass. Especially, coexistence of light and oxygen promote N recovery ratio to 70.9%, higher than with the other two conditions. Further, 93.7% of N-removed was synthesized into biomass. Finally, CO2 emission reduced by 62.6% compared with the traditional process. PSB wastewater treatment under this condition is energy-saving, highly effective, and environment friendly, and can achieve pollution control and resource recovery.