cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
It's OK to feel frustrated : how social comparison and motivational beliefs influence students' self-regulation
Creators: name: Lisaingo, Simon
Publisher: name: University of British Columbia
Year: 2016

description: During the learning process, frustration can be a significant obstacle for students, particularly in a classroom, when learners perceive that their peers can solve a problem more easily. The processes and beliefs that enable students to control their thoughts and actions to achieve personal goals are referred to as self-regulation. Dweck (1986; 2000) posited that the beliefs individuals have about their abilities, in particular about their intelligence, described as either a fixed or growth mindset, may mediate their use of self-regulatory strategies. An extension of Dweck’s research suggests that individuals also have beliefs about the amount of mental resources they have for exerting self- control (i.e., willpower) that are described as either limited or unlimited (Job, Dweck, & Walton, 2010). The purpose of the current study was to investigate how students’ beliefs about intelligence and willpower influenced their self-regulation during a potentially frustrating task with opportunities for social comparison. Participants in this study were public school students, aged 11 to 13 (N = 64; 40 female, 24 male), who were asked to solve puzzles in pairs. One student was given a solvable puzzle and the other was given an unsolvable puzzle. Students were not made aware of differences in the difficulty of the puzzle task before solving it. Questionnaires, observations, and performance on a cognitive task were used as measures of their beliefs, behaviours, emotions, and self- control. Data were analyzed using correlations, independent samples t-tests, and analysis of variance. Results indicated that the implemented experimental procedures induced frustration: students in the unsolvable condition displayed and self-reported greater frustration than students in the solvable condition. In addition, results indicated that frustration does not necessarily induce self-control depletion: no statistical difference was found in students’ self-control between conditions. However, students’ self- regulation was influenced by their beliefs about intelligence: students who viewed their intelligence as fixed demonstrated significantly greater self-control depletion than students who viewed their intelligence as capable of growing. Finally, results suggested that the concept of willpower may not be fully understood by students at this age: no significant results were found for the influence of students’ beliefs about willpower.
Phase slip phenomena in superconductors: from ordered to chaotic dynamics
Creators: name: Lu-Dac, Mathieu
name: Kabanov, V. V.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We consider flux penetration to a 2D superconducting cylinder. We show that in the low field limit the kinetics is deterministic. In the strong field limit the dynamics becomes stochastic. Surprisingly the inhomogeneity in the cylinder reduces the level of stochasticity because of the predominance of Kelvin-Helmholtz vortices.
description: 4 pages, 3 figures (main text) and 1 page, 1 figure (supplementary material)
Scaling Invariance in a Time-Dependent Elliptical Billiard
Creators: name: Oliveira, Diego F. M.
name: Robnik, Marko
Publisher: name: arXiv
Year: 2011
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We study some dynamical properties of a classical time-dependent elliptical billiard. We consider periodically moving boundary and collisions between the particle and the boundary are assumed to be elastic. Our results confirm that although the static elliptical billiard is an integrable system, after to introduce time-dependent perturbation on the boundary the unlimited energy growth is observed. The behaviour of the average velocity is described using scaling arguments.
Testing SDRT's Right Frontier
Creators: name: Afantenos, Stergos
name: Asher, Nicholas
Publisher: name: arXiv
Year: 2010
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: The Right Frontier Constraint (RFC), as a constraint on the attachment of new constituents to an existing discourse structure, has important implications for the interpretation of anaphoric elements in discourse and for Machine Learning (ML) approaches to learning discourse structures. In this paper we provide strong empirical support for SDRT's version of RFC. The analysis of about 100 doubly annotated documents by five different naive annotators shows that SDRT's RFC is respected about 95% of the time. The qualitative analysis of presumed violations that we have performed shows that they are either click-errors or structural misconceptions.
Partonic Transverse Motion in Unpolarized Semi-Inclusive Deep Inelastic Scattering Processes
Creators: name: Boglione, M.
name: Melis, S.
name: Prokudin, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We analyse the role of partonic transverse motion in unpolarized Semi-Inclusive Deep Inelastic Scattering (SIDIS) processes. Imposing appropriate kinematical conditions, we find some constraints which fix an upper limit to the range of allowed k_perp values. We show that, applying these additional requirements on the partonic kinematics, we obtain different results with respect to the usual phenomenological approach based on the Gaussian smearing with analytical integration over an unlimited range of k_perp values. These variations are particularly interesting for some observables, like the < cos phi_h > azimuthal modulation of the unpolarized SIDIS cross section or the average transverse momentum of the final, detected hadron.
description: 19 pages, 15 figures
The Radio - 2 mm Spectral Index of the Crab Nebula Measured with GISMO
Creators: name: Arendt, R. G.
name: George, J. V.
name: Staguhn, J. G.
name: Benford, D. J.
name: Devlin, M. J.
name: Dicker, S. R.
name: Fixsen, D. J.
name: Irwin, K. D.
name: Jhabvala, C. A.
name: Korngut, P. M.
name: Kovács, A.
name: Maher, S. F.
name: Mason, B. S.
name: Miller, T. M.
name: Moseley, S. H.
name: Navarro, S.
name: Sievers, A.
name: Sievers, J. L.
name: Sharp, E.
name: Wollack, E. J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present results of 2 mm observations of the Crab Nebula, obtained using the Goddard-IRAM Superconducting 2 Millimeter Observer (GISMO) bolometer camera on the IRAM 30 m telescope. Additional 3.3 mm observations with the MUSTANG bolometer array on the Green Bank Telescope are also presented. The integrated 2 mm flux density of the Crab Nebula provides no evidence for the emergence of a second synchrotron component that has been proposed. It is consistent with the radio power law spectrum, extrapolated up to a break frequency of log(nu_{b} [GHz]) = 2.84 +/- 0.29 or nu_{b} = 695^{+651}_{-336} GHz. The Crab Nebula is well-resolved by the ~16.7" beam (FWHM) of GISMO. Comparison to radio data at comparable spatial resolution enables us to confirm significant spatial variation of the spectral index between 21 cm and 2 mm. The main effect is a spectral flattening in the inner region of the Crab Nebula, correlated with the toroidal structure at the center of the nebula that is prominent in the near-IR through X-ray regime.
description: Accepted for publication in the ApJ
Mind the Gap: Formal Verification and the Common Criteria. (Discussion paper)
Creators: name: Beckert, Bernhard
name: Bruns, Daniel
name: Grebing, Sarah
Publisher: name: Karlsruhe
Year: 2010

description: It is a common belief that the rise of standardized software certification schemes like the Common Criteria (CC) would give a boost to formal verification, and that software certification may be a killer application for program verification. However, while formal models are indeed used throughout high-assurance certification, verification of the actual implementation is not required by the CC and largely neglected in certification practice -- despite the great advances in program verification over the last decade. In this paper we discuss the gap between program verification and CC software certification, and we point out possible uses of code-level program verification in the CC certification process.
Neutron Star Crust in Strong Magnetic Fields
Creators: name: Nandi, Rana
name: Bandyopadhyay, Debades
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We discuss the effects of strong magnetic fields through Landau quantization of electrons on the structure and stability of nuclei in neutron star crust. In strong magnetic fields, this leads to the enhancement of the electron number density with respect to the zero field case. We obtain the sequence of equilibrium nuclei of the outer crust in the presence of strong magnetic fields adopting most recent versions of the experimental and theoretical nuclear mass tables. For $B\sim 10^{16}$G, it is found that some new nuclei appear in the sequence and some nuclei disappear from the sequence compared with the zero field case. Further we investigate the stability of nuclei in the inner crust in the presence of strong magnetic fields using the Thomas-Fermi model. The coexistence of two phases of nuclear matter - liquid and gas, is considered in this case. The proton number density is significantly enhanced in strong magnetic fields $B\sim 10^{17}$G through the charge neutrality. We find nuclei with larger mass number in the presence of strong magnetic fields than those of the zero field. These results might have important implications for the transport properties of the crust in magnetars.
description: 6 pages including 3 figures; based on the talk presented at INPC2010, Vancouver; Submitted to the Proceedings of the conference in J. Phys. Conf. Ser
BM3D Frames and Variational Image Deblurring
Creators: name: Danielyan, Aram
name: Katkovnik, Vladimir
name: Egiazarian, Karen
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: A family of the Block Matching 3-D (BM3D) algorithms for various imaging problems has been recently proposed within the framework of nonlocal patch-wise image modeling [1], [2]. In this paper we construct analysis and synthesis frames, formalizing the BM3D image modeling and use these frames to develop novel iterative deblurring algorithms. We consider two different formulations of the deblurring problem: one given by minimization of the single objective function and another based on the Nash equilibrium balance of two objective functions. The latter results in an algorithm where the denoising and deblurring operations are decoupled. The convergence of the developed algorithms is proved. Simulation experiments show that the decoupled algorithm derived from the Nash equilibrium formulation demonstrates the best numerical and visual results and shows superiority with respect to the state of the art in the field, confirming a valuable potential of BM3D-frames as an advanced image modeling tool.
description: Submitted to IEEE Transactions on Image Processing on May 18, 2011. implementation of the proposed algorithm is available as part of the BM3D package at http://www.cs.tut.fi/~foi/GCF-BM3D
Tics and Swearing: a review of recent genetic data concerning Tourette Syndrome
Creators: name: Koulousi, Alexandra
name: Fidani, Liana
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: Tics; Genetics; Dopamine; Serotonin

description: Gilles de la Tourette Syndrome (TS) is a neurodevelopmental disorder characterized by a series of vocal and motor tics. It usually appears on childhood and affects 0.3-0.9% of the population, with the incidence ratio of boys: girls being 4:1. TS has a complex pathogenic basis, including genetic, epigenetic and environmental factors. It shows great heritability, but the underlying genetic etiology remains unclear. The purpose of this study was the review of the most important recent genetic discoveries concerning TS. The research was conducted mainly through studies and scientific articles dating 2010 and after. Over the last few years, genetic research over TS has linked the disease with SNPs (single nucleotide polymorphisms) and CNVs (copy number variants) of specific genes, mainly involved in the dopaminergic and serotoninergic path. Many genes have been associated with the disease, including DRD2 and D4 (dopamine receptors D2 and D4), DAT1 (dopamine transporter 1), TPH2 (tryptophan hydroxylase), MAO-A (monoamine oxidase -Α), with more recent studies pointing towards NRXN1 (neurexin 1) and CNTN6 (contactin 6) genes. A mutation of a gene leading to insufficiency of histamine decarboxylase has been named as a risk factor for the syndrome. In other studies, CNVs in AADAC (arylacetamide deacetylase) gene have also showed possible involvement in the onset and course of TS. Moreover, a recent genome-wide study associated an SNP in gene COL27A1 (collagen type ΧΧVΙΙ, alpha 1) with the disease. The recent genetic data in this field has led to the establishment of experimental genetically targeted therapies. Further scientific research over the genetics of TS is deemed necessary, as it can potentially lead to a personalized gene-targeted therapy to TS.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Polyol-vermittelte Synthese von Nanomaterialien für die heterogene Katalyse
Creators: name: Schmitt, Peter
Publisher: name: Karlsruhe
Year: 2011
Subjects: Nanomaterial
Molybdate
Tungstate
Catalysis
Photocatalysis

description: Starting from the particular metal nitrates (in the case of Co, Ni, Cu and Bi) or metal halogenides (in the case of Fe and In) the nanoscale vanadates, molybdates and tungstates Fe2(MoO4)3, CoMoO4, NiMoO4, CuMoO4, CuWO4, In2(MoO4)3 and BiVO4 are prepared at the nanoscale via a polyol-mediated approach
by using DEG as the chelating agent.
Computational analysis of transcriptional regulation from local sequence features to three dimensional chromatin domains
Creators: name: Chen, Julie Chih-Yu
Publisher: name: University of British Columbia
Year: 2017

description: Regulation of gene expression spans different levels of complexity: from genomic sequence, transcription factor binding and epigenetics, to three-dimensional chromatin interactions. Data from different individuals such as genetic variations presents an extra dimension to consider. Abnormal activities at any level may lead to disease phenotypes, motivating deeper exploration of gene regulation. New high-throughput sequencing techniques have empowered genome-wide studies of the regulatory mechanisms within cells. This thesis uses computational approaches to examine gene regulation with high-throughput data in order to address biological hypotheses traversing from short local sequence features to megabase-sized topologically associating domains (TADs). The hypotheses addressed in the thesis have two central themes: 1) the elucidation of local and domain regulation of gene expression, and 2) the application of such knowledge to identify functional phenotypic variants. We developed a computational approach to identify functional variants associated with cancer, and demonstrated how annotating regulatory sequences and linking these regions to target genes can strengthen genome interpretation. The concurrent and intertwined nature of local and domain regulation of gene expression develops as the thesis unfolds. In a study of genes that escape from X-chromosome inactivation, we found the YY1 transcription factor to be a key regulator, and is potentially associated with long distance chromatin looping mechanisms. Similarly, when studying the spread of inactivation to the autosomes in translocated cells, we detected local features associated with inactivation status, and at the domain level, we observed the spreading to be in accordance with TADs. Lastly, when considering TADs as transcriptional units, the identification of cell type-selectively co-expressed and co-localized TADs highlighted an organized and dynamic chromatin architecture across multiple cell types. In summary, this thesis provides insights into the mechanisms involved in gene expression across multiple scales (from local sequences to chromatin domains) using computational analyses on publicly available datasets. The presented methods and results have potential applications to interpret genetic variations and further our understanding in diseases and phenotypes. The findings may contribute to an era of preventative and regenerative medicine to come.
Anorexia nervosa and the role of the school counselor
Creators: name: Adamou, Christina
name: Dardavessis, Theodoros
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: Anorexia nervosa; school counselor role with anorexic students

description: Anorexia Nervosa is a tendency of eating minimal amount of food in order to avoid weight gain. It is included in what we call Eating Disorders. Anorexia is considered as an illness that has to do with low self-esteem often with tremendous desire to control their surroundings and emotions. This article describes anorexia Nervosa and it discusses the role that school counselors could play in the school setting., since they are in daily contact with the highest risk group for developing eating disorders-children and adolescents.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Unidentified family Group Photo
Creators: name: Kelsey, Carleton
name: Amagansett Historical Association
Publisher: name: Unknown
Year: 0
Subjects: Photographs
People
Men
Women

description: This image is of a group of people consisting of 6 women and two men. The identities of the people in this photo are unknown. This photograph was either taken or collected by Amagansett historian and librarian Carleton Kelsey.
description: This photograph is part of the collection of the Carleton Kelsey Collection of the Amagansett Historical Association. Kelsey was a local historian and librarian who collected photographs from others to add to the many photographs he took of the community himself.
Multiple Sclerosis and cognitive dysfunctions
Creators: name: Adamou, Christina
name: Dardavessis, Theodoros
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: Multiple Sclerosis; cognitive dysfunctions in multiple sclerosis

description: Multiple Sclerosis (MS) is the most common neurological disease worldwide. The article presents the symptoms, the etiology and the diagnosis of MS. It also refers to the neuropsychological data and cognitive disorders in Multiple Sclerosis, to the MS treatment and to the developments in MS research.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Search for a heavy gauge boson W' in the final state with an electron and large missing transverse energy in pp collisions at sqrt(s) = 7 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for a heavy gauge boson W' has been conducted by the CMS experiment at the LHC in the decay channel with an electron and large transverse energy imbalance, using proton-proton collision data corresponding to an integrated luminosity of 36 inverse picobarns. No excess above standard model expectations is seen in the transverse mass distribution of the electron-(missing E_T) system. Assuming standard-model-like couplings and decay branching fractions, a W' boson with a mass less than 1.36 TeV/c^2 is excluded at 95% confidence level.
description: CMS-EXO-10-014, CERN-PH-EP-2010-074
The Novel Visibility of Myocarditis. From pathology to treatment
Creators: name: Avagimyan, Ashot
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: myocardium; inflammation; cardiotoxicity; heart attack; non-coronary disease

description: Myocarditis is one of the most common non-coronary diseases, since it is associated with many infectious and immune-allergic diseases, such as HIV, hepatitis, systemic bacterial and fungal infections. Moreover, this nosological form can be also associated with the side effects of various medicines. For instance, some chemotherapeutic drugs, such as trastuzumab used to treat breast cancer, are able to trigger the myocarditis development. Understanding of mechanisms of the myocarditis development under the similar drugs action, and awareness of a physician about their high risk will help him to avoid undesirable complications, and thereby, to increase the survival rate and standard of living of the world’s population. This article has incorporated all the aspects of the classification, etiology, pathogenesis, morphogenesis, as well as the clinical manifestations, diagnosis and treatment.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Numerical Investigation on the Thermal Performance of a Hospital Ward Roof Incorporating Phase Change Material (PCM)
Creators: name: Riya, Anika Rahman
name: Rafe Md. Abu Zayed
name: Sumaiya Saima Sharmi
Publisher: name: figshare
Year: 2020
Subjects: subject: Mechanical Engineering
subject: FOS: Mechanical engineering
subject: 10301 Numerical Analysis
subject: FOS: Mathematics

description: Overheating is a common phenomenon in a tropical country like Bangladesh. So, ensuring the thermal comfort of hospital patients is necessary for proper health treatment. But in Bangladesh, the thermal comfort of the patient is compromised as installation of the air conditioning system in every general ward of the hospital is impossible due to economic constraints. So, a cheap but effective solution is badly needed to cope with this situation. In that case, PCM (phase change materials) can be an alternative to improve the thermal condition and reduce temperature fluctuation in hospitals in Bangladesh. Phase changing ability at a constant temperature and latent heat storage property of PCM have been proved very effective for the improvement of building thermal condition over the years. In this study, the improvement of thermal condition of the general ward of Patuakhali Medical College (PkMC) is analyzed using PCM as a retrofitting option. A numerical simulation work is performed to analyze and compare the effect of three different PCMs on the enhancement of thermal comfort hours. Finally, based on the result, the best PCM is chosen for optimum thermal management.
An in silico method for studying the phosphorylation in association to active sites
Creators: name: Galliou, Panagiota Angeliki
name: Verrou, Kleio-Maria
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: Phosphorylation; Prediction; Kinases; Active Sites; Bioinformatics

description: Post-translational modifications (PTMs) occur to a vast amount of proteins and the most common post-translational modification (PTM) is phosphorylation. Phosphorylation and dephosphorylation, regulate protein functionality by turning the protein active sites (sites with important biological function) on and off. Therefore, identification of a protein’s phosphorylated residues and determination of their role are of paramount importance, especially for proteins driving diseases. Notwithstanding the multiple methodologies for identifying phosphorylated residues, literature lacks of methodologies for determination of their role. For this reason, we created a method that aims to enhance the understanding of a protein’s regulation by phosphorylation as well as to aid the design of more directed and lower-cost experiments. Our method uses the PhosphoKin tool, which predicts new phosphorylated residues in a given protein sequence, identifies the possibly responsible kinases for the protein’s experimentally observed phosphorylated residues and links all phosphorylated residues as well as their kinases with the protein’s active sites. Our method assesses the impact of the examined kinases in the protein’s phosphorylation and is suitable for associations between specific group of kinases and active sites. Also, it suggests the illustration of a phosphorylation map of the protein that is useful for further analysis.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Comparative Study and Application of the EFA-4 Diagnostic Tool to Alzheimer’s Disease and Mild Cognitive Impairment
Creators: name: Erkotidou, Sofia
name: Nasios, Grigorios
name: Arnaoutoglou, Marianthi
name: Tafiadis, Dionisios
name: Tsolaki, Magda
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: EFA-4; Speech Disorders; Dementia; AD; Mild Cognitive Impairment; MCI

description: Speech is a cortical function that includes virtual, mobile and sensory part for the understanding and the expression of spoken and written word. This study shows the Greek adaptation of the diagnostic tool «Examining for aphasia» or EFA -4. In dementia and especially in Alzheimer’s disease–AD, the speech disorders are among the main diagnostic feature, along with the impairment of memory. How, however, will we recognize Dementia and separate it from the early stage of Mild Cognitive Impairment- MCI according to speech disorders? The diagnostic tool EFA-4 is a regulatory, reliable and valid measure of the speech disorders. The test was administered to 50 normal elders, 50 patients with AD and 31 patients with MCI. The sample selection, although it had a uniform age, was regardless of origin, marital status and socioeconomic status. According to the results of the research, the EFA-4 is perceived to be particularly useful in the setting of language deficits of the patients with AD, who participated in the survey. Specifically, the cut offs showed that the average of the EFA-4 for the normal range ranged from 74,5 – 74,8. Moreover the cut offs showed that the average of EFA-4 for patients with AD ranges from 36.8-46.1 and for patients with MCI ranges from 62.2 - 66.7.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
XMM-Newton observations of IGRJ18410-0535: The ingestion of a clump by a supergiant fast X-ray transient
Creators: name: Bozzo, E.
name: Giunta, A.
name: Cusumano, G.
name: Ferrigno, C.
name: Walter, R.
name: Campana, S.
name: Falanga, M.
name: Israel, G.
name: Stella, L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: IGRJ18410-0535 is a supergiant fast X-ray transients. This subclass of supergiant X-ray binaries typically undergoes few- hour-long outbursts reaching luminosities of 10^(36)-10^(37) erg/s, the occurrence of which has been ascribed to the combined effect of the intense magnetic field and rotation of the compact object hosted in them and/or the presence of dense structures ("clumps") in the wind of their supergiant companion. IGR J18410-0535 was observed for 45 ks by XMM-Newton as part of a program designed to study the quiescent emission of supergiant fast X-ray transients and clarify the origin of their peculiar X-ray variability. We carried out an in-depth spectral and timing analysis of these XMM-Newton data. IGR J18410-0535 underwent a bright X-ray flare that started about 5 ks after the beginning of the observation and lasted for \sim15 ks. Thanks to the capabilities of the instruments on-board XMM-Newton, the whole event could be followed in great detail. The results of our analysis provide strong convincing evidence that the flare was produced by the accretion of matter from a massive clump onto the compact object hosted in this system. By assuming that the clump is spherical and moves at the same velocity as the homogeneous stellar wind, we estimate a mass and radius of Mcl \simeq1.4\times10^(22) g and Rcl \simeq8\times10^(11) cm. These are in qualitative agreement with values expected from theoretical calculations. We found no evidence of pulsations at \sim4.7 s after investigating coherent modulations in the range 3.5 ms-100 s. A reanalysis of the archival ASCA and Swift data of IGR J18410-0535, for which these pulsations were previously detected, revealed that they were likely to be due to a statistical fluctuation and an instrumental effect, respectively.
description: Accepted for publication on A&A. V2: Inserted correct version of Fig.16
Comparative study of efficiency on prototype against generic drugs on lipid lowering agents
Creators: name: Karkanis, George
name: Karavanis, Emmanuel
name: Farmakis, Nikolaos
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: generic drugs; prototype drugs; lipid lowering agents; vessels' endothelium; vessels' walls; statin; fibrate; lipid drugs

description: The purpose of the current study is to approve or disprove the efficiency of the effectiveness comparing generic drugs and the respectively prototype drugs on lipid lowering agents based on two specific quality factors; first the thickness of the vessels' endothelium and second the calcification on vessels' walls. For the study drugs where recognized and divided into two categories: Unique drugs which included prototype drugs with protected exclusivity of the use of the active substance (on patent) according to the law. And generic drugs which NOM has given approvals as generic drugs.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Strong color fields and heavy flavor production
Creators: name: Pajares, C.
name: Bautista, I.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The clustering of color sources provides a natural framework for soft partonic interactions producing strong color fields. We study the consequences of these color fields in the production of heavy flavor and the behavior of the nuclear modification factor.
description: 11 pages, 7 figures, to appear in Physical Review C
Dissecting human lymphoma using an integrated network analysis
Creators: name: Seitanidou, Charikleia
name: Orfanoudaki, Georgia
name: Mavridou, Dimitra
name: Pitsikali, Aikaterini
name: Drakos, Elias
name: Psatha, Konstantina
name: Aivaliotis, Michalis
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: lymphoma; p53; integration; transciptomics; proteomics

description: Lymphomas are cancers that originate in the lymphatic system. Despite the heterogeneity, lymphomas are characterized by the deregulation of the p53-signaling pathway. This study describes a systems-wide network analysis of the key mal-functioning p53-centered network of interactions involved in lymphoma pathogenesis through integration of transcriptomic and proteomic data.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Source-level instrumentation for in-system debug of high-level synthesis designs for FPGA
Creators: name: Pinilla, Jose Pablo
Publisher: name: University of British Columbia
Year: 2016

description: High-Level Synthesis (HLS) has emerged as a promising technology to reduce the time and complexity that is associated with the design of digital logic circuits. HLS tools are capable of allocating resources and scheduling operations from a software-like behavioral specification. In order to maintain the productivity promised by HLS, it is important that the designer can debug the system in the context of the high-level code. Currently, software simulations offer a quick and familiar method to target logic and syntax bugs, while software/hardware co-simulations are useful for synthesis verification. However, to analyze the behaviour of the circuit as it is running, the user is forced to understand waveforms from the synthesized design. Debugging a system as it is running requires inserting instrumentation circuitry that gathers data regarding the operation of the circuit, and a database that maps the record entries to the original high-level variables. Previous work has proposed adding this instrumentation at the Register Transfer Level (RTL) or in the high-level source code. Source-level instrumentation provides advantages in portability, transparency, and customization. However, previous work using source-level transformations has focused on the ability to expose signals for observation rather than the construction of the instrumentation itself, thereby limiting these advantages by requiring lower-level code manipulation. This work shows how trace buffers and related circuitry can be inserted by automatically modifying the source-level specification of the design. The transformed code can then be synthesized using the regular HLS flow to generate the instrumented hardware description. The portability of the instrumentation is shown with synthesis results for Vivado HLS and LegUp, and compiled for Xilinx and Altera devices correspondingly. Using these HLS tools, the impact on circuit size varies from 15.3% to 52.5% and the impact on circuit speed ranges from 5.8% to 30%. We also introduce a low overhead technique named Array Duplicate Minimization (ADM) to improve trace memory efficiency. ADM improves overall debug observability by removing up to 31.7% of data duplication created between the trace memory and the circuit{'}s memory structures.
Phonon-mediated decoherence in triple quantum dot interferometers
Creators: name: Domínguez, Fernando
name: Kohler, Sigmund
name: Platero, Gloria
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate decoherence in a triple quantum dot in ring configuration in which one dot is coupled to a damped phonon mode, while the other two dots are connected to source and drain, respectively. In the absence of decoherence, single electron transport may get blocked by an electron falling into a superposition decoupled from the drain and known as dark state. Phonon-mediated decoherence affects this superposition and leads to a finite current. We study the current and its shot noise numerically within a master equation approach for the electrons and the dissipative phonon mode. A polaron transformation allows us to obtain a reduced equation for only the dot electrons which provides analytical results in agreement with numerical ones.
description: 9 pages, 6 figures
Dark-bright mixing of interband transitions in symmetric semiconductor quantum dots
Creators: name: Sallen, G.
name: Urbaszek, B.
name: Glazov, M. M.
name: Ivchenko, E. L.
name: Kuroda, T.
name: Mano, T.
name: Kunz, S.
name: Abbarchi, M.
name: Sakoda, K.
name: Lagarde, D.
name: Balocchi, A.
name: Marie, X.
name: Amand, T.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In photoluminescence spectra of symmetric [111] grown GaAs/AlGaAs quantum dots in longitudinal magnetic fields applied along the growth axis we observe in addition to the expected bright states also nominally dark transitions for both charged and neutral excitons. We uncover a strongly non-monotonous, sign changing field dependence of the bright neutral exciton splitting resulting from the interplay between exchange and Zeeman effects. Our theory shows quantitatively that these surprising experimental results are due to magnetic-field-induced \pm 3/2 heavy-hole mixing, an inherent property of systems with C_3v point-group symmetry.
description: 5 pages, 3 figures
Deciphering the role of autophagy and exosomes in human lymphoma
Creators: name: Kalantidou, Aikaterini
name: Karkavitsa, Anna-Aspasia
name: Orfanoudaki, Georgia
name: Mavridou, Dimitra
name: Pitsikali, Aikaterini
name: Kollipara, Laxmikanth
name: Sickmann, Albert
name: Rassidakis, George
name: Drakos, Elias
name: Psatha, Konstantina
name: Aivaliotis, Michalis
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: lymphoma; Nutlin-3a; proteomics; autophagy; exosomes

description: The orchestrated homeostatic action of autophagy and exosome biogenesis provides a potential causal relation with lymphomagenesis. This study aims to characterize the differently expressed proteins associated with both above-mentioned pathways, as well as to explore their potential implication in therapeutic response controlling lymphomagenesis via N3a-induced re-activated p53 in different lymphoma subtypes.
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Magnetic moment of Ag-104(m) and the hyperfine magnetic field of Ag in Fe using nuclear magnetic resonance on oriented nuclei
Creators: name: Golovko, V. V.
name: Kraev, I. S.
name: Phalet, T.
name: Delaure, B.
name: Beck, M.
name: Kozlov, V. Yu.
name: Coeck, S.
name: Wauters, F.
name: Herzog, P.
name: Tramm, Ch.
name: Zakoucky, D.
name: Venos, D.
name: Srnka, D.
name: Honusek, M.
name: Koester, U.
name: Severijns, N.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Nuclear magnetic resonance (NMR/ON) measurements with beta- and gamma-ray detection have been performed on oriented Ag-104(g,m) nuclei with the NICOLE He-3-He-4 dilution refrigerator setup at ISOLDE/CERN. For Ag-104(g) (I-pi = 5(+)) the gamma-NMR/ON resonance signal was found at nu = 266.70(5) MHz. Combining this result with the known magnetic moment for this isotope, the magnetic hyperfine field of Ag impurities in an Fe host at low temperature (< 1 K) is found to be vertical bar B-hf(AgFe)vertical bar = 44.709(35) T. A detailed analysis of other relevant data available in the literature yields three more values for this hyperfine field. Averaging all four values yields a new and precise value for the hyperfine field of Ag in Fe; that is, vertical bar B-hf(AgFe)vertical bar = 44.692(30) T. For Ag-104(m) (I-pi = 2(+)), the anisotropy of the beta particles provided the NMR/ON resonance signal at nu = 627.7(4) MHz. Using the new value for the hyperfine field of Ag in Fe, this frequency corresponds to the magnetic moment mu(Ag-104m) = +3.691(3) mu(N), which is significantly more precise than previous results. The magnetic moments of the even-A Ag102 -110 isotopes are discussed in view of the competition between the (pi g(9/2))(7/2+)(-3)(nu d(5/2)nu g(7/2))(5/2+) and the (pi g(9/2))(9/2+)(-3)(nu d(5/2)nu g(7/2))(5/2+) configurations. The magnetic moments of the ground and isomeric states of Ag-104 can be explained by an almost complete mixing of these two configurations.
description: 12 pages, 7 figures
George Whitney
Creators: name: Kelsey, Carleton
name: Amagansett Historical Association
Publisher: name: Unknown
Year: 2000
Subjects: Photographs
Men

description: This image is of George Whitney of Amagansett on September 16, 2000. This photograph was either taken or collected by Amagansett historian and librarian Carleton Kelsey.
description: This photograph is part of the collection of the Carleton Kelsey Collection of the Amagansett Historical Association. Kelsey was a local historian and librarian who collected photographs from others to add to the many photographs he took of the community himself.
Engineering chromium related single photon emitters in single crystal diamond
Creators: name: Aharonovich, I
name: Castelletto, S
name: Johnson, B C
name: McCallum, J C
name: Prawer, S
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Color centers in diamond as single photon emitters, are leading candidates for future quantum devices due to their room temperature operation and photostability. The recently discovered chromium related centers are particularly attractive since they possess narrow bandwidth emission and a very short lifetime. In this paper we investigate the fabrication methodologies to engineer these centers in monolithic diamond. We show that the emitters can be successfully fabricated by ion implantation of chromium in conjunction with oxygen or sulfur. Furthermore, our results indicate that the background nitrogen concentration is an important parameter, which governs the probability of success to generate these centers.
description: 14 pages, 5 figures
LDL and HDL lipoprotein subtype frequency in patients with rheumatoid arthritis before and after administration of anti–TNFα
Creators: name: Karakota, Maria
name: Zakalka, Marina
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: lipoproteins; LDL subtypes; HDL subtypes; anti-TNFα; rheumatoid arthritis

description: A higher risk of atherosclerosis and related cardiovascular disease has been observed in patients with rheumatoid arthritis. Anti-TNFα monoclonal antibodies are used for the treatment of resistant rheumatoid arthritis resulting in inhibition of TNFα binding to cellular receptors that activate disease-associated pro-inflammatory pathways. The effect of TNFα inhibition on the lipoprotein pattern may provide information on the risk of atherosclerosis in these patients. In the present study the lipoprotein profiles of patients with rheumatoid arthritis have been examined before and after treatment with anti-TNFα. 85 patients (76 women, 89%) with established RA (disease duration ≥5 years), mean age 57 ± 12 (68% with RF positive), no known cardiovascular disease, thyroid disorder and thyroid disorder’s treatment with DMARDs and not receiving biological agents as treatment, were divided into 2 groups, those who had DAS28 3.2 (43 patients) who were additionally reserved anti-TNFα biological factor for ≥12 months and those who had DAS28≤3.2 (42 patients) who continued DMARD treatment and were monitored at the same time as a control group. Samples were taken at two times with a difference of ≥12 months. Separation of the lipoprotein subtypes was done by 4% polyacrylamide native gel electrophoresis. Two LDL (LDLA and LDL B) and six HDL (HDL1, HDL2a, HDL2b, HDL3a, HDL3b and HDL3c) subtypes were characterized. In patients receiving DMARDs, a decrease in the LDL-B subtype by 11.9% (p = 0.014) and an increase in HDL-3c by 2.38% (p = 0.049) were observed. In PA patients receiving anti-TNFα, a reduction in the LDL-B subtype was observed by 2.33% (p = 0.005), LDL-A by 2.33% (p = 0.0001), HDL3a by 11.63% = 0.072) and HDL3c by 4.65% (p = 0.035). In RA patients receiving anti-TNFα, a reduction in the LDL-B fractions was observed by 2.33% (p = 0.005), LDL-A by 2.33% (p = 0.0001), HDL3a by 11.63% = 0.072) and HDL3c by 4.65% (p = 0.035).
description: Aristotle Biomedical Journal, Vol 1, No 1 (2019)
Herschel-ATLAS: The link between accretion luminosity and star formation in quasar host galaxies
Creators: name: Bonfield, D. G.
name: Jarvis, M. J.
name: Hardcastle, M. J.
name: Cooray, A.
name: Hatziminaoglou, E.
name: Ivison, R. J.
name: Page, M. J.
name: Stevens, J. A.
name: de Zotti, G.
name: Auld, R.
name: Baes, M.
name: Buttiglione, S.
name: Cava, A.
name: Dariush, A.
name: Dunlop, J. S.
name: Dunne, L.
name: Dye, S.
name: Eales, S.
name: Fritz, J.
name: Hopwood, R.
name: Ibar, E.
name: Maddox, S. J.
name: Michałowski, M. J.
name: Pascale, E.
name: Pohlen, M.
name: Rigby, E. E.
name: Rodighiero, G.
name: Serjeant, S.
name: Smith, D. J. B.
name: Temi, P.
name: van der Werf, P.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We use the science demonstration field data of the Herschel-ATLAS to study how star formation, traced by the far-infrared Herschel data, is related to both the accretion luminosity and redshift of quasars selected from the Sloan Digital Sky Survey and the 2SLAQ survey. By developing a maximum likelihood estimator to investigate the presence of correlations between the far-infrared and optical luminosities we find evidence that the star-formation in quasar hosts is correlated with both redshift and quasar accretion luminosity. Assuming a relationship of the form L_IR \propto L_QSO^θ (1 + z)^ζ, we find θ = 0.22 +/- 0.08 and ζ = 1.6 +/- 0.4, although there is substantial additional uncertainty in ζ of order +/- 1, due to uncertainties in the host galaxy dust temperature. We find evidence for a large intrinsic dispersion in the redshift dependence, but no evidence for intrinsic dispersion in the correlation between L_QSO and L_IR, suggesting that the latter may be due to a direct physical connection between star formation and black hole accretion. This is consistent with the idea that both the quasar activity and star formation are dependent on the same reservoir of cold gas, so that they are both affected by the influx of cold gas during mergers or heating of gas via feedback processes.
description: 10 pages, accepted for publication in MNRAS (compared with v1, this version has a very slightly expanded discussion of the comparison to other work)
Morphological characteristics on a Scanning Electron Microscope of generated hyaline cartilage tissue from adipose mesenchymal stem cells, on Polycaprolactone scaffolds
Creators: name: Pappi, Eleni
name: Theodoridis, Konstantinos
name: Aggelidou, Eleni
name: Manthou, Maria Eleni
name: Kritis, Aristeidis
Publisher: name: Aristotle Biomedical Journal
Year: 2019
Subjects: cartilage, regeneration, 3d printing technology, polycaprolactone, scaffolds, scanning electron microscope

description: Cartilage regeneration is of great interest to the medical community, given the prevalence of osteocartilage defects in the population coupled with the tissue’s low intrinsic self-repair potential. A recently new FDA approved biomaterial and 3D-printing technology provided us the opportunity to fabricate tailor made scaffolds. We used collagen coated and uncoated scaffolds to develop hyaline cartilage from adipose mesenchymal stem cells (ADMSCs). The aim of this study is to present the scaffolds’ morphological characteristics, as observed on a Scanning Electron Microscope (SEM) of generated cartilage tissue and to compare the two types of scaffolds. Cylindrical shaped PCL scaffolds, 10mm in diameter, were fabricated. ADMSCs were harvested and were cultivated on PCL scaffolds. Half of the scaffolds were treated with collagen I by coating. After 26 days in culture, the scaffolds were examined by SEM. Visualization was succeeded on the top and bottom surfaces and on the cross sections of each scaffold. At day 26, scaffolds revealed extensive colonization and viability of ADMSCs, with concurrent depositions of extracellular matrix. SEM images show that surfaces were covered with a significant amount of material with a glossy, transparent appearance, indicating the development of regenerated cartilage, more apparent on the coated scaffolds. Cultured cells demonstrated aligned direction on the scaffolds' fibers and the ECM that was produced connected the pores of the scaffolds by building apparent bridges between them. The penetration of cells was limited in the coated scaffold. We used 3D printing technology for PCL scaffold production, towards a cartilaginous implant development. SEM images provide us visualization of the scaffolds with the newly developed cartilage tissue and demonstrate that the scaffolds’ purpose for chondrogenesis was served successfully in all cases and PCL displayed good biocompatibility. Collagenation of scaffolds led to a higher density of cells on the surfaces but also to a limited penetration within, not fully serving the purpose of a 3D culture.
description: Aristotle Biomedical Journal, Vol 1, No 2 (2019)