cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Vanishing Hall Resistance at High Magnetic Field in a Double Layer Two-Dimensional Electron System
Creators: name: Kellogg, M.
name: Eisenstein, J. P.
name: Pfeiffer, L. N.
name: West, K. W.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: At total Landau level filling factor $ν_{tot}=1$ a double layer two-dimensional electron system with small interlayer separation supports a collective state possessing spontaneous interlayer phase coherence. This state exhibits the quantized Hall effect when equal electrical currents flow in parallel through the two layers. In contrast, if the currents in the two layers are equal, but oppositely directed, both the longitudinal and Hall resistances of each layer vanish in the low temperature limit. This finding supports the prediction that the ground state at $ν_{tot}=1$ is an excitonic superfluid.
description: 4 pages, 4 figures
title: Von der Anmut der Wirklichkeit: Ein Interview mit Olga Černyševa
Creators: name: Widder, Roman
Publisher: name: Fachinformationsdienst Slavistik
Year: 2009
Subjects: subject: Černyševa, Olga
subject: Russisch
subject: Fotografie
subject: Künstlerin
subject: Interview
subject: 491.8

description: Sie entwickelt ihre Bilder in Schokoladefarben, packt Menschen und Pflanzen in Plastikhüllen ein, filmt in Zügen, auf Märkten oder Märschen. Olga Černyševas Arbeiten spüren in mikroskopischen Beobachtungen dem postsowjetischen Alltag nach und zeigen seine Schönheit auf.
description: novinkizurückgefragt, no. 2009-01-10
Investigating the effects of different weight loss interventions on eating behaviour and reward-driven eating in patients with obesity and type-2 diabetes
Creators: name: Alessimii, Haya
Publisher: name: Imperial College London
Year: 2020

description: Obesity has become a global health issue, and type-2 diabetes (T2DM) is one of its most common comorbidities. The Roux-en-Y gastric bypass (RYGB) is the most effective surgical procedure for treating obesity, resulting in significant and sustainable weight loss. One proposed mechanism for how RYGB achieves successful weight-loss is based on profound changes in the secretion of gastrointestinal hormones that follow surgery, including increases in Glucagon-Like Peptide-1, Oxyntomodulin and Peptide YY (GOP). Surgically induced changes in physiology are also associated with specific behavioural factors and psychological characteristics, both of which are recognised as important contributors to successful postoperative outcome. This study hypothesised that patients with obesity and T2DM following RYGB have a healthier eating behaviour profile, mediating the long-term sustainable weight loss than Very-Low-Calorie diet (VLCD) or GOP infusion. Eating behaviour, food reward, psychological status, health-related quality of life and food intake were assessed at baseline and following each intervention using a set of validated questionnaires and a 4-day food-diary before and after each intervention. The RYGB showed a reduction in the reward drive to eat at three-month which was maintained up to one-year post-surgery. There were also reductions in external-eating, disinhibition and weight and shape concerns which were not observed following VLCD or GOP, suggesting that calorie-restriction or gut-hormone alone maybe not be responsible for changes in eating behaviour following RYGB. Meanwhile, there were similarities between the RYGB and GOP groups in terms of the increase in the flexible dietary restraint measured by the Dutch Eating Behaviour questionnaire. Moreover, the GOP group did not show any changes in the taste perception as were observed following RYGB. Understanding the behavioural mechanisms that account for such variations could help the development of personalised therapeutic approaches based on the need to improve treatment outcomes and dietary advice offered to patients with obesity.
Refined algebraic quantisation with the triangular subgroup of SL(2,R)
Creators: name: Louko, Jorma
name: Molgado, Alberto
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We investigate refined algebraic quantisation with group averaging in a constrained Hamiltonian system whose gauge group is the connected component of the lower triangular subgroup of SL(2,R). The unreduced phase space is T^*R^{p+q} with p>0 and q>0, and the system has a distinguished classical o(p,q) observable algebra. Group averaging with the geometric average of the right and left invariant measures, invariant under the group inverse, yields a Hilbert space that carries a maximally degenerate principal unitary series representation of O(p,q). The representation is nontrivial iff (p,q) is not (1,1), which is also the condition for the classical reduced phase space to be a symplectic manifold up to a singular subset of measure zero. We present a detailed comparison to an algebraic quantisation that imposes the constraints in the sense H_a Psi = 0 and postulates self-adjointness of the o(p,q) observables. Under certain technical assumptions that parallel those of the group averaging theory, this algebraic quantisation gives no quantum theory when (p,q) = (1,2) or (2,1), or when p>1, q>1 and p+q is odd.
description: 30 pages. LaTeX with amsfonts, amsmath, amssymb. (v4: Typos corrected. Published version.)
Incorporating Food Attributes in the Demand for Food: A Cross-Section Study of Oyster Consumption
Creators: name: Lin, Chung-Tung Jordan
name: Milon, J. Walter
name: Lin, Chung-Tung Jordan
name: Milon, J. Walter
Publisher: name: Unknown
Year: 1991
Subjects: Demand and Price Analysis
Food Consumption/Nutrition/Food Safety

description: This study examines the relationship between consumer's product attribute perceptions, especially food safety perceptions, and long-term consumption of oysters. Statistical analysis of consumer survey data shows that attribute perceptions are significantly associated with both market participation and level of consumption decisions. Yet, safety perception had a negligible behavioral impact.
Plasma-Lyte solution versus saline in kidney transplantation: a systematic review and meta?analysis of randomized controlled trials
Creators: name: Chang, Yucai
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 320214
subject: Nephrology and urology

description: AbstractIntroduction The optimal intravenous fluid for kidney transplantation (KT) is still controversial. This meta?analysis aimed to compare the efficacy and safety of plasma-lyte solution (PL) versus saline (NS) in kidney transplantation.Materials and Methods Four databases (PubMed, Embase, Web of Science, and the Cochrane Library) were searched for trials comparing plasma-lyte and saline in kidney transplantation. Primary outcome was delayed graft function (DGF). Secondary outcomes included creatinine levels, urine output, blood pH, bicarbonate, base excess , electrolytes, serum chloride, potassium and sodium immediately post-surgery. Results Totally six randomized controlled studies with 1197 patients were included. In comparison to the NS group, the PL group exhibited a significantly lower incidence of DGF (OR: 0.66, 95% CI: 0.51 to 0.86, P = 0.002) and reduced serum chloride (MD: -8.87, 95% CI: -13.50 to -4.25, P=0.0002) as well as serum sodium(MD: -1.08, 95% CI: -1.54 to -0.61, P < 0.00001), while blood pH(MD: 0.05, 95% CI: 0.03 to 0.07, P < 0.00001), bicarbonate (MD: 2.09, 95% CI: 1.21 to 2.97, P=0.005), and base excess levels (MD: 2.42, 95% CI: 0.72 to 4.11, P < 0.00001) were significantly elevated. No statistically significant differences were observed in creatinine, urine output, or potassium concentrations between two groups.Conclusions This meta-analysis compared the efficacy and safety between plasma-lyte and saline in kidney transplantation. Plasma-lyte reduced delayed graft function in kidney transplant compared to saline.
Timber : timber is a full-size, electromechanical tree. It dies if you are careless.
Creators: name: Shkuratoff, Alexander
Publisher: name: The University of British Columbia
Year: 2014

description: Disclaimer: “UBC SEEDS provides students with the opportunity to share the findings of their studies, as well as their opinions, conclusions and recommendations with the UBC community. The reader should bear in mind that this is a student project/report and is not an official document of UBC. Furthermore readers should bear in mind that these reports may not reflect the current status of activities at UBC. We urge you to contact the research persons mentioned in a report or the SEEDS Coordinator about the current status of the subject matter of a project/report.”
The initial boundary value problem on the segment for the Nonlinear Schrödinger equation; the algebro-geometric approach. I
Creators: name: Grinevich, P. G.
name: Santini, P. M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Algebraic Geometry (math.AG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: This is the first of a series of papers devoted to the study of classical initial-boundary value problems of Dirichlet, Neumann and mixed type for the Nonlinear Schrödinger equation on the segment. Considering proper periodic discontinuous extensions of the profile, generated by suitable point-like sources, we show that the above boundary value problems can be rewritten as nonlinear dynamical systems for suitable sets of algebro-geometric spectral data, generalizing the classical Dubrovin equations. In this paper we consider, as a first illustration of the above method, the case of the Dirichlet problem on the segment with zero-boundary value at one end, and we show that the corresponding dynamical system for the spectral data can be written as a system of ODEs with algebraic right-hand side.
description: 29 pages, LaTeX, 2 Encapsulated Postscript figures
Treatments for chronic pruritus outside of the box
Creators: name: Metz, Martin
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: atopic dermatitis
subject: itch
subject: neurokinin-1
subject: prurigo
subject: urticaria
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Patients with chronic pruritus are in desperate need of novel treatment options, as current therapeutic possibilities are often not effective, have a poor level of evidence and are mostly off-label. In recent years, much effort has been put into the identification of potential targets for the treatment of chronic pruritus. More importantly, a number of promising new drugs that are aimed at treating pruritus in different conditions are currently in advanced stages of clinical trials. Here, current pharmacological developments leading to potential new drugs for the treatment of chronic pruritus within various conditions are summarized. Hopefully, these new approaches will result in effective and safe therapies for our patients with chronic pruritus associated with dermatological or non-dermatological diseases in the near future.
title: Molecular mechanisms for the regulation of the Il-10 gene in CD4 T cells : comparison of IL-10-Tregand CD25+Treg.
Creators: name: Shoemaker, John
Publisher: name: The Open University
Year: 2006

description: This thesis outlines and provides direct evidence for transcription factor-mediated instructive regulation of the 11-10 gene in CD4 T cells. Firstly, I describe transcription factors that are differentially expressed in populations of IL-10-producing CD4 T cells. Genome-wide mRNA profiles (GeneChip) are used from six populations of CD4 T populations which represent both temporal and lineage-specific time-points within naive, effector and regulatory CD4 T cell populations. Secondly, validation experiments (qPCR) verified whether transcription factors isolated from the genome-wide profiling experiments (GeneChip) were quantitatively expressed in IL-10-producing populations. Thirdly, comparative genomics was used to analyze in silico the 11-10 locus for conserved putative transcription factor binding sites at potential regulatory regions. Selected transcription factors were retro-virally transduced into primary naive CD4 T cells and analyzed for their ability to induce IL-10 expression in a variety of differentiation conditions. Finally, the role of functionally validated transcription factors inducing IL-10 production was investigated at the molecular level, via their presence at specific locations at the 11-10 locus in vivo and in chromatin modifications. One example, GATA-3, shown here to be differentially expressed in IL-10-producing CD4 T cell populations, instructing modifications at the 11-10 locus and inducing IL-10 production in CD4 T cells.

The second aim of this thesis was to investigate — at the transcription factor-level -- the comparison of two phenotypically different CD4 regulatory T cell populations (CD25+Treg and IL-10-Treg). On one hand, both CD4 T regulatory cell populations are similar in that they do not produce effector upon secondary stimuli, both are anergic, and both suppress CD4 T cell proliferation in vitro and in vivo (as shown by their ability to abrogate multiple autoimmune and allergic disease animal models). On the other hand, CD25+Treg are phenotypically described by their expression of the lineage-specific transcription factor, FoxP3, and IL-10- Treg do not express FoxP3. Therefore, the molecular mechanisms as to how IL-10- Treg do not express effector cytokines, are anergic and suppress CD4 T cell proliferation in vitro and in vivo without the expression of FoxP3 is investigated in this thesis. This thesis concludes by providing strong evidence that IL-10-Treg down-regulate key NF-kB and AP-1 family transcripts and inhibit NFAT transcriptional activity, thereby compensating for FoxP3 expression, which is necessary in natural occurring CD25+Treg.
Dynamical study of $γ^*N \leftrightarrow Δ$ transition with $N(e,e'p)π$
Creators: name: Yang, S. N.
name: Kamalov, S. S.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Dubna-Mainz-Taipei (DMT) dynamical model for pion electromagnetic production, which describe well the existing data from threshold up to 1 GeV photon lab energy is presented and used to analyze recent data in the $Δ$ region . We find that within DMT model, the bare $Δ$ is almost spherical while the physical $Δ$ is oblate. The deformation is almost saturated by the pion cloud effects.
description: 4 pages, 2 postscript figures, contr. to Int. Conf. on QCD and Hadronic Physics, Beijing from Jun 16-20, 2005
Degas and the Dancers Dancers : Sculpture and Drawings
Creators: name: Kensey, Danyelle M.
name: Broude, Norma
Publisher: name: American University (Washington, D.C.)
Year: 2023
Subjects: classificationCode: 3601
subject: Art history, theory and criticism

description: Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis option
IsoTV: processing and visualizing functional features of translated transcript isoforms
Creators: name: Annaldasula, Siddharth
name: Gajos, Martyna
name: Mayer, Andreas
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: translated transcript isoforms
subject: visualization
subject: functional features
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Despite the continuous discovery of new transcript isoforms, fueled by the recent increase in accessibility and accuracy of long-read RNA sequencing data, functional differences between isoforms originating from the same gene often remain obscure. To address this issue and enable researchers to assess potential functional consequences of transcript isoform variation on the proteome, we developed IsoTV. IsoTV is a versatile pipeline to process, predict and visualize the functional features of translated transcript isoforms. Attributes such as gene and isoform expression, transcript composition and functional features are summarized in an easy-to-interpret visualization. IsoTV is able to analyze a variety of data types from all eukaryotic organisms, including short- and long-read RNA-seq data. Using Oxford Nanopore long read data, we demonstrate that IsoTV facilitates the understanding of potential protein isoform function in different cancer cell types.
МОДИФИЦИРОВАННОЕ ЛЕЧЕНИЕ ВТОРИЧНОГО ХРОНИЧЕСКОГО ПИЕЛОНЕФРИТА У ДЕТЕЙ
Creators: name: И.А.Ахмеджанов,, Самаркандский Государственный Медицинский университет
name: Н.И. Ахмеджанова, Самаркандский Государственный Медицинский университет
name: Изомиддинова М.К., Самаркандский Государственный Медицинский университет
Publisher: name: Zenodo
Year: 2024

description: Целью работы является оценка влияния региональной лимфатической терапии (РЛТ) +канефрона + электрофореза с эуфиллином на некоторые показатели эндогенной интоксикации(ЭИ) и функционального состояния почек (ФСП) при хроническом дисметаболическом пиелонефрите (ХДП). Проведено обследование 70 детей, больных ХДП, в возрасте от 4 до 14 лет. Больные были разделены на 4 группы в зависимости от метода лечения. Сравнительная оценка результатов исследования ФСП и показателей ЭИпоказала высокую эффективность комплексного применения РЛТ+канефрон+электрофорез с эуфиллином, который мы назвали «почечным тюбажем».
High‐resolution diffusion‐weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients
Creators: name: Hotter, Benjamin
name: Galinovic, Ivana
name: Kunze, Claudia
name: Brunecker, Peter
name: Jungehulsing, Gerhard J.
name: Villringer, Arno
name: Endres, Matthias
name: Villringer, Kersten
name: Fiebach, Jochen B.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: diffusion magnetic resonance imaging
subject: transient ischemic attack
subject: neuroimaging
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Transient ischemic attack (TIA) is defined as focal neurological deficit caused by ischemia resolving within 24 hours. In a secondary analysis of a large monocentric cohort of 446 TIA patients, we explored the frequency and determinants of diffusion-weighted imaging (DWI) lesions on high-resolution magnetic resonance imaging. Overall, 240 (54%) of all TIA patients presented with DWI lesions. These patients had higher National Institute of Health Stroke Scale and ABCD2 scores and presented more frequently with vessel occlusion and perfusion deficits, but had similar functional outcome at 3 months. Taken together, high-resolution DWI provides evidence of ischemic brain injury in the majority of TIA patients. ANN NEUROL 2019
Measuring the Colombian "Success" story
Creators: name: AE Feldmann
Publisher: name: University of Illinois at Chicago
Year: 2021
Subjects: Uncategorized

description: This article discusses the evolution of state capacity in Colombia. Drawing on the general debate regarding the conceptualization and measurement of the state, the piece tracks the record of the Colombian state in the last decade. The article posits that, contrary to the conventional wisdom, the strength of the Colombian state has increased only marginally in the last 10 years. This improvement derives from important gains in two of Michael Mann's (1986) infrastructural power dimensions -territorial reach and bureaucratic capacity. Lack of substantial improvements in Mann's third infrastructural dimension- autonomy vis-à-vis non-states actors- and setbacks in the state legitimacy dimension make the gains in state capacity modest rather than robust.
Multi-Goal Prior Selection: A Way to Reconcile Bayesian and Classical Approaches for Random Effects Models
Creators: name: Hirose, Masayo Y.
name: Partha Lahiri
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The two-level normal hierarchical model has played an important role in statistical theory and applications. In this paper, we first introduce a general adjusted maximum likelihood method for estimating the unknown variance component of the model and the associated empirical best linear unbiased predictor of the random effects. We then discuss a new idea for selecting prior for the hyperparameters. The prior, called a multi-goal prior, produces Bayesian solutions for hyperparmeters and random effects that match (in the higher order asymptotic sense) the corresponding classical solution in linear mixed model with respect to several properties. Moreover, we establish for the first time an analytical equivalence of the posterior variances under the proposed multi-goal prior and the corresponding parametric bootstrap second-order mean squared error estimates in the context of a random effects model.
Mixed Integer Programming for Searching Maximum Quasi-Bicliques
Creators: name: Ignatov, Dmitry I.
name: Ivanova, Polina
name: Zamaletdinova, Albina
Publisher: name: arXiv
Year: 2020
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Artificial Intelligence (cs.AI)
subject: Discrete Mathematics (cs.DM)
subject: Social and Information Networks (cs.SI)
subject: Optimization and Control (math.OC)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: G.2.2; I.5.3
subject: 68R10, 90C11

description: This paper is related to the problem of finding the maximal quasi-bicliques in a bipartite graph (bigraph). A quasi-biclique in the bigraph is its "almost" complete subgraph. The relaxation of completeness can be understood variously; here, we assume that the subgraph is a $γ$-quasi-biclique if it lacks a certain number of edges to form a biclique such that its density is at least $γ\in (0,1]$. For a bigraph and fixed $γ$, the problem of searching for the maximal quasi-biclique consists of finding a subset of vertices of the bigraph such that the induced subgraph is a quasi-biclique and its size is maximal for a given graph. Several models based on Mixed Integer Programming (MIP) to search for a quasi-biclique are proposed and tested for working efficiency. An alternative model inspired by biclustering is formulated and tested; this model simultaneously maximizes both the size of the quasi-biclique and its density, using the least-square criterion similar to the one exploited by triclustering \textsc{TriBox}.
description: This paper draft is stored here for self-archiving purposes
Load‐induced osteogenic differentiation of mesenchymal stromal cells is caused by mechano‐regulated autocrine signaling
Creators: name: Schreivogel, Sophie
name: Kuchibhotla, Virinchi
name: Knaus, Petra
name: Duda, Georg N.
name: Petersen, Ansgar
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: autocrine signaling
subject: bioreactor
subject: bone morphogenetic protein type 2
subject: cell migration
subject: mechanical loading
subject: osteogenic differentiation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Mechanical boundary conditions critically influence the bone healing process. In this context, previous in vitro studies have demonstrated that cyclic mechanical compression alters migration and triggers osteogenesis of mesenchymal stromal cells (MSC), both processes being relevant to healing. However, it remains unclear whether this mechanosensitivity is a direct consequence of cyclic compression, an indirect effect of altered supply or a specific modulation of autocrine bone morphogenetic protein (BMP) signaling. Here, we investigate the influence of cyclic mechanical compression (ε = 5% and 10%, f = 1 Hz) on human bone marrow MSC (hBMSC) migration and osteogenic differentiation in a 3D biomaterial scaffold, an in vitro system mimicking the mechanical environment of the early bone healing phase. The open-porous architecture of the scaffold ensured sufficient supply even without cyclic compression, minimizing load-associated supply alterations. Furthermore, a large culture medium volume in relation to the cell number diminished autocrine signaling. Migration of hBMSCs was significantly downregulated under cyclic compression. Surprisingly, a decrease in migration was not associated with increased osteogenic differentiation of hBMSCs, as the expression of RUNX2 and osteocalcin decreased. In contrast, BMP2 expression was significantly upregulated. Enabling autocrine stimulation by increasing the cell-to-medium ratio in the bioreactor finally resulted in a significant upregulation of RUNX2 in response to cyclic compression, which could be reversed by rhNoggin treatment. The results indicate that osteogenesis is promoted by cyclic compression when cells condition their environment with BMP. Our findings highlight the importance of mutual interactions between mechanical forces and BMP signaling in controlling osteogenic differentiation.
Four Painters of African American Life, 1920-1940
Creators: name: Kensey, Danyelle M.
name: Langa, Helen
Publisher: name: American University (Washington, D.C.)
Year: 2023
Subjects: classificationCode: 3601
subject: Art history, theory and criticism

description: Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis option
Pupil dilation as an implicit measure of appetitive Pavlovian learning
Creators: name: Pietrock, Charlotte
name: Ebrahimi, Claudia
name: Katthagen, Teresa M.
name: Koch, Stefan P.
name: Heinz, Andreas
name: Rothkirch, Marcus
name: Schlagenhauf, Florian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: associative learning
subject: attention
subject: eye-tracking
subject: pupil dilation
subject: reward
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Appetitive Pavlovian conditioning is a learning mechanism of fundamental biological and pathophysiological significance. Nonetheless, its exploration in humans remains sparse, which is partly attributed to the lack of an established psychophysiological parameter that aptly represents conditioned responding. This study evaluated pupil diameter and other ocular response measures (gaze dwelling time, blink duration and count) as indices of conditioning. Additionally, a learning model was used to infer participants' learning progress on the basis of their pupil dilation. Twenty-nine healthy volunteers completed an appetitive differential delay conditioning paradigm with a primary reward, while the ocular response measures along with other psychophysiological (heart rate, electrodermal activity, postauricular and eyeblink reflex) and behavioral (ratings, contingency awareness) parameters were obtained to examine the relation among different measures. A significantly stronger increase in pupil diameter, longer gaze duration and shorter eyeblink duration was observed in response to the reward-predicting cue compared to the control cue. The Pearce-Hall attention model best predicted the trial-by-trial pupil diameter. This conditioned response was corroborated by a pronounced heart rate deceleration to the reward-predicting cue, while no conditioning effect was observed in the electrodermal activity or startle responses. There was no discernible correlation between the psychophysiological response measures. These results highlight the potential value of ocular response measures as sensitive indices for representing appetitive conditioning.
Exponentially Localized Magnetic Fields for Single-Spin Quantum Logic Gates
Creators: name: Lidar, Daniel A.
name: Thywissen, Joseph H.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: An infinite array of parallel current-carrying wires is known, from the field of neutral particle optics, to produce an exponentially localized magnetic field when the current direction is antiparallel in adjacent wires. We show that a finite array of several tens of superconducting Nb nanowires can produce a peak magnetic field of 10mT that decays by a factor of 10^4 over a length scale of 500nm. Such an array is readily manufacturable with current technology, and is compatible with both semiconductor and superconducting quantum computer architectures. A series of such arrays can be used to individually address single single-spin or flux qubits spaced as little as 100nm apart, and can lead to quantum logic gate times of 5ns.
description: 5 pages, incl. 4 figures
Earnings Distributions of Scalable vs. Non-Scalable Occupations, Supplemental Material
Creators: name: Silva, Sergio Da
name: Matsushita, Raul
name: Maia, Adriano
Publisher: name: figshare
Year: 2020
Subjects: subject: 20304 Thermodynamics and Statistical Physics
subject: FOS: Mechanical engineering

description: Supplemental material for the paper Earnings Distributions of Scalable vs. Non-Scalable Occupations.
THE EXACT MSE—EFFICIENCY OF THE GENERAL RIDGE ESTIMATOR RELATIVE TO OLS
Creators: name: Teekens, R.
name: De Boer, P. M. C.
name: Teekens, R.
name: De Boer, P. M. C.
Publisher: name: Unknown
Year: 1977
Subjects: Agricultural and Food Policy
Research Methods/ Statistical Methods

description: In this paper it has been pointed out that the merits of the Ridge procedure as proposed by Hoerl and Kennard tend to be overvalued due to an incorrect analysis of the associated Mean Square Error. For the case of the so-called General Ridge Estimator it is then shown how the exact MSE can be derived and finally it is seen that General Ridge Estimator dominates the OLS estimator .only in a limited interval of the parameter space.
Modulation of μ‐opioid receptor activation by acidic pH is dependent on ligand structure and an ionizable amino acid residue
Creators: name: Meyer, Johanna
name: Del Vecchio, Giovanna
name: Seitz, Viola
name: Massaly, Nicolas
name: Stein, Christoph
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: HEK293 cells
subject: μ-opioid receptor
subject: ligands
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background and Purpose: Adverse side effects of conventional opioids can be avoided if ligands selectively activate peripheral opioid receptors in injured tissue. Injury and inflammation are typically accompanied by acidification. In this study, we examined influences of low pH and mutation of the ionizable amino acid residue H297(6.52) on mu-opioid receptor binding and signalling induced by the mu-opioid receptor ligands fentanyl, DAMGO, and naloxone. Experimental Approach: HEK 293 cells stably transfected with mu-opioid receptors were used to study opioid ligand binding, [S-35]-GTP gamma S binding, and cAMP reduction at physiological and acidic pH. We used mu-opioid receptors mutated at H297(6.52) to A (MOR-H297(6.52)A) to delineate ligand-specific interactions with H297(6.52). Key Results: Low pH and the mutant receptor MOR-H297(6.52)A impaired naloxone binding and antagonism of cAMP reduction. In addition, DAMGO binding and G-protein activation were decreased under these conditions. Fentanyl-induced signalling was not influenced by pH and largely independent of H297(6.52). Conclusions and Implications: Our investigations indicate that low pH selectively impairs mu-opioid receptor signalling modulated by ligands capable of forming hydrogen bonds with H297(6.52). We propose that protonation of H297(6.52) at acidic pH reduces binding and subsequent signalling of such ligands. Novel agonists targeting opioid receptors in injured tissue might benefit from lack of hydrogen bond formation with H297(6.52).
Charmonium levels near threshold and the narrow state $X(3872) \to π^{+}π^{-}\jpsi$
Creators: name: Eichten, Estia J.
name: Lane, Kenneth
name: Quigg, Chris
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We explore the influence of open-charm channels on charmonium properties, and profile the 1:3D2, 1:3D3 and 2:1P1 charmonium candidates for X(3872). The favored candidates, the 1:3D2 and 1:3D3 levels, both have prominent radiative decays. The 1:3D2 might be visible in the $D^{0}\bar{D}^{*0}$ channel, while the dominant decay of the 1:3D3 state should be into $D\bar{D}$. We propose that additional discrete charmonium levels can be discovered as narrow resonances of charmed and anticharmed mesons.
description: 8 pages, 6 figures, uses RevTeX and boxedeps; few transcription errors corrected in Tables IV and VI, three entries added in Table V, updated references. Version to appear in Phys. Rev. D
A 37 kb region upstream of brachyury comprising a notochord enhancer is essential for notochord and tail development
Creators: name: Schifferl, Dennis
name: Scholze-Wittler, Manuela
name: Wittler, Lars
name: Veenvliet, Jesse V.
name: Koch, Frederic
name: Herrmann, Bernhard G.
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: Mouse
subject: Embryo
subject: Development
subject: Notochord
subject: Brachyury
subject: Enhancer
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: The node-streak border region comprising notochord progenitor cells (NPCs) at the posterior node and neuro-mesodermal progenitor cells (NMPs) in the adjacent epiblast is the prime organizing center for axial elongation in mouse embryos. The T-box transcription factor brachyury (T) is essential for both formation of the notochord and maintenance of NMPs, and thus is a key regulator of trunk and tail development. The T promoter controlling T expression in NMPs and nascent mesoderm has been characterized in detail; however, control elements for T expression in the notochord have not been identified yet. We have generated a series of deletion alleles by CRISPR/Cas9 genome editing in mESCs, and analyzed their effects in mutant mouse embryos. We identified a 37 kb region upstream of T that is essential for notochord function and tailbud outgrowth. Within that region, we discovered a T-binding enhancer required for notochord cell specification and differentiation. Our data reveal a complex regulatory landscape controlling cell type-specific expression and function of T in NMP/nascent mesoderm and node/notochord, allowing proper trunk and tail development.
A NOTE ON THE ESTIMATION OF THE PARAMETERS OF A MULTIPLICATIVE ALLOCATION MODEL
Creators: name: Teekens, R.
name: Jansen, R.
name: Teekens, R.
name: Jansen, R.
Publisher: name: Unknown
Year: 1977
Subjects: Agricultural and Food Policy
Research Methods/ Statistical Methods

description: In this note the estimation of the parameters of a multiplicative allocation model is achieved on the basis of a procedure which consists of (1) a log transformation, (ii)a linear transformation which eliminates the "noise" term due to the denominator in the original model. The procedure is applicable under fairly general assumptions and provides BLU estimators, which are linear in the logarithm of the explanatory variable.
Gender Biases in the Criticisms of Helen Frankenthaler
Creators: name: Okin, Jobi Marlitt
name: Langa, Helen
Publisher: name: American University (Washington, D.C.)
Year: 2023
Subjects: classificationCode: 3601
subject: Art history, theory and criticism

description: Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as thesis option
Urban vertebrate ecology of the Pacific Northwest, with recommendations for wildlife stewardship at UBC Vancouver
Creators: name: Garber, Philipp
Publisher: name: The University of British Columbia
Year: 2014

description: Over the last century, urban areas in western North America have seen tremendous growth. Major human settlements are often strategically located at the mouth of rivers, along inlets or in valley bottoms, such as Vancouver, Seattle, or Portland. These areas are also of high value to wildlife. As cities expand, habitat is reduced, altered, and fragmented. While many vertebrates have been displaced from some of their original range, some species are able to take advantage of novel foraging opportunities and reduced predation, while adapting to challenges in communication and movement. Not only is UBC’s Vancouver campus surrounded by Pacific Spirit Regional Park – its location along the Pacific Flyway gives UBC responsibility in terms of global biodiversity. UBC can improve its wildlife stewardship by facilitating movement and providing opportunities to forage, rest, and breed, as well as by encouraging students, staff, faculty, and visitors to collaborate on future initiatives. Disclaimer: “UBC SEEDS provides students with the opportunity to share the findings of their studies, as well as their opinions, conclusions and recommendations with the UBC community. The reader should bear in mind that this is a student project/report and is not an official document of UBC. Furthermore readers should bear in mind that these reports may not reflect the current status of activities at UBC. We urge you to contact the research persons mentioned in a report or the SEEDS Coordinator about the current status of the subject matter of a project/report.”
Sonia Delaunay and the Art of Fashion
Creators: name: Ruiz, Marisa S.
name: Broude, Norma
Publisher: name: American University (Washington, D.C.)
Year: 2023
Subjects: classificationCode: 3601
subject: Art history, theory and criticism

description: Research paper submitted to American University in partial fulfillment of the Degree of Master of Arts; approved as non-thesis option
Quantum Nernst Effect
Creators: name: Nakamura, Hiroaki
name: Hatano, Naomichi
name: Shirasaki, Ryoen
Publisher: name: arXiv
Year: 2005
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report our recent predictions on the quantum Nernst effect, a novel thermomagnetic effect in the quantum Hall regime. We assume that, when the chemical potential is located between a pair of neighboring Landau levels, edge currents convect around the system. This yields theoretical predictions that the Nernst coefficient is strongly suppressed and the thermal conductance is quantized. The present system is a physical realization of the non-equilibrium steady state.
description: 4 pages, 2 figures. To be published in the proceedings of ISQM-TOKYO '05 available online at: http://www.worldscibooks.com/physics/6153.html
ON THE NOTION OF PROBABILITY: A SURVEY
Creators: name: De Leede, E.
name: Koerts, J.
name: De Leede, E.
name: Koerts, J.
Publisher: name: Unknown
Year: 1977
Subjects: Agricultural and Food Policy
Research Methods/ Statistical Methods

description: Different interpretations of the probability concept are considered. In a situation of repeated trials, indepedent in the frequentistic sense, the frequentistic theory appears to be adequate only if a sufficiently large number of observations is available. In those cases where only a limited number of observations is available, the subjectivistic approach towards probability might be of help. The underlying assumptions of this notion of probability are considered. From the fundamentals of normative probabilities, the ambiguity of a prior distribution for an "unknown" parameter is shown: Sometimes such a prior distribution can be considered as a reflection of (personal) beliefs, sometimes it must be considered as a derivative of the learning process that is chosen. When these two .interpretations overlap, the meaning of a prior distribution becomes rather vague.
Human gestational N‐methyl‐d‐aspartate receptor autoantibodies impair neonatal murine brain function
Creators: name: Jurek, Betty
name: Chayka, Mariya
name: Kreye, Jakob
name: Lang, Katharina
name: Kraus, Larissa
name: Fidzinski, Pawel
name: Kornau, Hans‐Christian
name: Dao, Le‐Minh
name: Wenke, Nina K.
name: Long, Melissa
name: Rivalan, Marion
name: Winter, York
name: Leubner, Jonas
name: Herken, Julia
name: Mayer, Simone
name: Mueller, Susanne
name: Boehm‐Sturm, Philipp
name: Dirnagl, Ulrich
name: Schmitz, Dietmar
name: Kölch, Michael
name: Prüss, Harald
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: autoantibodies
subject: N-methyl-d-aspartate receptor
subject: pregnancy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objective: Maternal autoantibodies are a risk factor for impaired brain development in offspring. Antibodies (ABs) against the NR1 (GluN1) subunit of the N-methyl-d-aspartate receptor (NMDAR) are among the most frequently diagnosed anti-neuronal surface ABs, yet little is known about effects on fetal development during pregnancy. Methods: We established a murine model of in utero exposure to human recombinant NR1 and isotype-matched nonreactive control ABs. Pregnant C57BL/6J mice were intraperitoneally injected on embryonic days 13 and 17 each with 240μg of human monoclonal ABs. Offspring were investigated for acute and chronic effects on NMDAR function, brain development, and behavior. Results: Transferred NR1 ABs enriched in the fetus and bound to synaptic structures in the fetal brain. Density of NMDAR was considerably reduced (up to -49.2%) and electrophysiological properties were altered, reflected by decreased amplitudes of spontaneous excitatory postsynaptic currents in young neonates (-34.4%). NR1 AB-treated animals displayed increased early postnatal mortality (+27.2%), impaired neurodevelopmental reflexes, altered blood pH, and reduced bodyweight. During adolescence and adulthood, animals showed hyperactivity (+27.8% median activity over 14 days), lower anxiety, and impaired sensorimotor gating. NR1 ABs caused long-lasting neuropathological effects also in aged mice (10 months), such as reduced volumes of cerebellum, midbrain, and brainstem. Interpretation: The data collectively support a model in which asymptomatic mothers can harbor low-level pathogenic human NR1 ABs that are diaplacentally transferred, causing neurotoxic effects on neonatal development. Thus, AB-mediated network changes may represent a potentially treatable neurodevelopmental congenital brain disorder contributing to lifelong neuropsychiatric morbidity in affected children.
Au(i)-mediated N2-elimination from triazaphospholes: a one-pot synthesis of novel N2P2-heterocycles
Creators: name: Yue, Erlin
name: Dettling, Lea
name: Sklorz, Julian A. W.
name: Kaiser, Selina
name: Weber, Manuela
name: Müller, Christian
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: coordination chemistry
subject: phosphorus-compounds
subject: crystal-structures
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Novel tosyl- and mesitylsulfonyl-substituted triazaphospholes were synthesized and structurally characterized. In an attempt to prepare the corresponding Au(I)-complexes with stoichiometric amounts of AuCl·S(CH3)2, cyclo-1,3-diphospha(III)-2,4-diazane-AuCl-complexes were obtained instead. Our here presented results offer a new strategy for preparing such coordination compounds selectively in a one-pot approach.
Elder-Rule-Staircodes for Augmented Metric Spaces
Creators: name: Cai, Chen
name: Kim, Woojin
name: Memoli, Facundo
name: Wang, Yusu
Publisher: name: arXiv
Year: 2020
Subjects: subject: Algebraic Topology (math.AT)
subject: Computational Geometry (cs.CG)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: An augmented metric space is a metric space $(X, d_X)$ equipped with a function $f_X: X \to \mathbb{R}$. This type of data arises commonly in practice, e.g, a point cloud $X$ in $\mathbb{R}^d$ where each point $x\in X$ has a density function value $f_X(x)$ associated to it. An augmented metric space $(X, d_X, f_X)$ naturally gives rise to a 2-parameter filtration $\mathcal{K}$. However, the resulting 2-parameter persistent homology $\mathrm{H}_{\bullet}(\mathcal{K})$ could still be of wild representation type, and may not have simple indecomposables. In this paper, motivated by the elder-rule for the zeroth homology of 1-parameter filtration, we propose a barcode-like summary, called the elder-rule-staircode, as a way to encode $\mathrm{H}_0(\mathcal{K})$. Specifically, if $n = |X|$, the elder-rule-staircode consists of $n$ number of staircase-like blocks in the plane. We show that if $\mathrm{H}_0(\mathcal{K})$ is interval decomposable, then the barcode of $\mathrm{H}_0(\mathcal{K})$ is equal to the elder-rule-staircode. Furthermore, regardless of the interval decomposability, the fibered barcode, the dimension function (a.k.a. the Hilbert function), and the graded Betti numbers of $\mathrm{H}_0(\mathcal{K})$ can all be efficiently computed once the elder-rule-staircode is given. Finally, we develop and implement an efficient algorithm to compute the elder-rule-staircode in $O(n^2\log n)$ time, which can be improved to $O(n^2α(n))$ if $X$ is from a fixed dimensional Euclidean space $\mathbb{R}^d$, where $α(n)$ is the inverse Ackermann function.
description: A few important questions considered in the previous version have been settled; see Example 4.12 and Section 4.3 in particular. The paper has been reorganized. This is the full version of the paper in the Proceedings of the 36th International Symposium on Computational Geometry (SoCG 2020); 41 pages, 17 figures
Sharing Classical Secrets with Continuous-Variable Entanglement: Composable Security and Network Coding Advantage
Creators: name: Walk, Nathan
name: Eisert, Jens
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: Quantum cryptography
subject: Quantum entanglement
subject: Quantum networks
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Secret sharing is a multiparty cryptographic primitive that can be applied to a network of partially distrustful parties for encrypting data that is both sensitive (it must remain secure) and important (it must not be lost or destroyed). When sharing classical secrets (as opposed to quantum states), one can distinguish between protocols that leverage bipartite quantum key distribution (QKD) and those that exploit multipartite entanglement. The latter class are known to be vulnerable to so-called participant attacks and, while progress has been made recently, there is currently no analysis that quantifies their performance in the composable, finite-size regime, which has become the gold standard for QKD security. Given this—and the fact that distributing multipartite entanglement is typically challenging—one might well ask is there any virtue in pursuing multipartite entanglement-based schemes? Here, we answer this question in the affirmative for a class of secret-sharing protocols based on continuous-variable graph states. We establish security in a composable framework and identify a network topology, specifically a bottleneck network of lossy channels, and parameter regimes within the reach of present-day experiments for which a multipartite scheme outperforms the corresponding QKD-based method in the asymptotic and finite-size setting. Finally, we establish experimental parameters where the multipartite schemes outperform any possible QKD-based protocol. This is one of the first concrete compelling examples of multipartite entangled resources achieving a genuine advantage over point-to-point protocols for quantum communication and represents a rigorous, operational benchmark to assess the usefulness of such resources.