Dietary intake of vitamin B6 and concentration of vitamin B 6 in blood samples of German vegans
Creators: name: Waldmann, A.
name: Dörr, B.
name: Koschizke, J.W.
name: Leitzmann, C.
name: Hahn, A.
Publisher: name: Cambridge : Cambridge University Press
Year: 2006
Subjects: subject: Dietary intake
subject: EAST-AC
subject: Veganism
subject: Vitamin B6
subject: aspartate aminotransferase
subject: pyridoxine
subject: vitamin B complex
subject: adult
subject: article
subject: blood sampling
subject: dietary intake
subject: enzyme activity
subject: ethnicity
subject: female
subject: human
subject: human experiment
subject: logistic regression analysis
subject: male
subject: nutrition
subject: priority journal
subject: questionnaire
subject: vitamin blood level
subject: vitamin supplementation
subject: bioavailability
subject: blood
subject: clinical trial
subject: cross-sectional study
subject: enzymology
subject: erythrocyte
subject: Germany
subject: metabolism
subject: multicenter study
subject: nutritional assessment
subject: nutritional status
subject: pyridoxine deficiency
subject: statistical model
subject: vegetarian diet
subject: Lens culinaris
subject: Adult
subject: Aspartate Aminotransferases
subject: Biological Availability
subject: Cross-Sectional Studies
subject: Diet, Vegetarian
subject: Erythrocytes
subject: Female
subject: Humans
subject: Logistic Models
subject: Male
subject: Nutrition Assessment
subject: Nutritional Status
subject: Questionnaires
subject: Vitamin B 6
subject: Vitamin B 6 Deficiency
subject: Vitamin B Complex
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit

description: Objective: The study aimed to evaluate the dietary vitamin B6 intake and determine the vitamin B6 concentration in blood samples of German vegans. Design and setting: Cross-sectional study with 33 examination sites all over Germany. Subjects: Ninety-three vegans (50 females) with a mean (± standard deviation (SD)) age of 43.7 ± 15.7 years who took no vitamin supplements. Methods: Dietary intake was assed using a semi-quantitative food-frequency questionnaire. Erythrocyte aspartate aminotransferase activity coefficient (EAST-AC) was calculated as the ratio of stimulated (pyridoxal 5′-phosphate added) to unstimulated activity in blood samples that were provided after an overnight fast. Results: Mean ± SD vitamin B 6 intake was 2.83 ± 0.98 mg day-1 and mean ± SD protein intake was 56.6 ± 21.7 g day-1. Of the participants 4% showed vitamin B6 intakes lower than daily recommended intakes for Germany, 16% showed EAST-AC &gt; 1.85, and a further 58% showed EAST-AC of 1.5-1-85. Moderate vegans were affected to a lesser extent than strict vegans. None of the established confounders was a significant predictor of EAST-AC. In logistic regression analyses the contribution of nutriments and cereals to pyridoxine intake was the only predictor of EAST-AC classified as ≤ 1.85 and &gt; 1.85, respectively. Conclusions: In spite of the high total intake of vitamin B6, an adequate concentration in blood samples could not be realised for a majority of the participants. Due to the health implications of a marginal pyridoxine status, vegans should be encouraged to include foods with a high bioavailability of pyridoxine, such as beans, lentils and bananas, in the daily diet.