cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Insights into the Versatility of Using Atomic Absorption Spectrometry in Antibacterial Research
Creators: name: Krüger, David
name: Matshwele, James T. P.
name: Mukhtar, Muhammad Dauda
name: Baecker, Daniel
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: antibiotics
subject: atomic absorption spectrometry
subject: cephalosporin
subject: complexation
subject: fluoroquinolone
subject: mode of action
subject: molecular absorption spectrometry
subject: nanoparticles
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: The ongoing development of bacterial resistance to antibiotics is a global challenge. Research in that field is thus necessary. Analytical techniques are required for such a purpose. From this perspective, the focus was on atomic absorption spectrometry (AAS). Although it is old, AAS often offers unexpected potential. Of course, this should be exploited. The aim was therefore to demonstrate the versatility of the technique in antibacterial research. This is illustrated by various examples of its practical application. AAS can be used, for example, to confirm the identity of antibacterial compounds, for purity controls, or to quantify the antibiotics in pharmaceutical preparations. The latter allowed analysis without laborious sample preparation and without interference from other excipients. In addition, AAS can help elucidate the mode of action or resistance mechanisms. In this context, quantifying the accumulation of the antibiotic drug in the cell of (resistant) bacteria appears to play an important role. The general application of AAS is not limited to metal-containing drugs, but also enables the determination of some organic chemical antibiotics. Altogether, this perspective presents a range of applications for AAS in antibacterial research, intending to raise awareness of the method and may thus contribute to the fight against resistance.
British Columbia Hospitals: examination and assessment of payment reform (B-CHeaPR)
Creators: name: Sutherland, Jason M.
name: McGrail, Kimberlyn M.
name: Law, Michael R.
name: Barer, M. L.
name: Trafford Crump, R.
Publisher: name: BioMed Central
Year: 2015

description: Abstract Background Accounting for 36% of public spending on health care in Canada, hospitals are a major target for cost reductions through various efficiency initiatives. Some provinces are considering payment reform as a vehicle to achieve this goal. With few exceptions, Canadian provinces have generally relied on global and line-item budgets to contain hospital costs. There is growing interest amongst policy-makers for using activity based funding (ABF) as means of creating financial incentives for hospitals to increase the 'volume' of care, reduce cost, discourage unnecessary activity, and encourage competition. British Columbia (B.C.) is the first province in Canada to implement ABF for partial reimbursement of acute hospitalization. To date, there have been no formal examinations of the effects of ABF policies in Canada. This study proposal addresses two research questions designed to determine whether ABF policies affect health system costs, access and hospital quality. The first question examines the impact of the hospital funding policy change on internal hospital activity based on expenditures and quality. The second question examines the impact of the change on non-hospital care, including readmission rates, amount of home care provided, and physician expenditures. Methods/Design A longitudinal study design will be used, incorporating comprehensive population-based datasets of all B.C. residents; hospital, continuing care and physician services datasets will also be used. Data will be linked across sources using anonymized linking variables. Analytic datasets will be created for the period between 2005/2006 and 2012/2013. Discussion With Canadian hospitals unaccustomed to detailed scrutiny of what services are provided, to whom, and with what results, the move toward ABF is significant. This proposed study will provide evidence on the impacts of ABF, including changes in the type, volume, cost, and quality of services provided. Policy- and decision-makers in B.C. and elsewhere in Canada will be able to use this evidence as a basis for policy adaptations and modifications. The significance of this proposed study derives from the fact that the change in hospital funding policy has the potential to affect health system costs, residents' access to care and care quality.
Challenges to self-care and domestic life for adults with disproportionate short statured skeletal dysplasia: a mixed method systematic review
Creators: name: Prescelia, Chyntia
name: Ireland, Penelope J.
name: Blanco, Celeste
name: Nguyen, Daphne
name: Pacey, Verity
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: This review aims to assess the impact of pain and limitations across self-care and domestic tasks among adults with disproportionate short statured skeletal dysplasia (SD). A systematic search was conducted across six electronic databases without language or year of publication restrictions from the date of inception of each database through to 31 July 2024. Clear inclusion criteria were established before search initiation and quality assessment was performed using the Mixed Methods Appraisal Tool (MMAT). Eight studies including 1,114 adults (mean age 33.1 years) met the inclusion criteria, demonstrating high methodological quality (MMAT ranging from 80 to 100%). Challenges in self-care and domestic tasks were prevalent among adults with disproportionate short statured SD. Personal hygiene (65.6%, 95% confidence interval (95%CI): 55.3–74.6%), donning/doffing shoes (54.3%, 95%CI: 38.2–70.0%), and reaching objects (20.2%, 95%CI: 16.8–24.1%) were the most prevalent difficulties, generally falling within low-moderate difficulty. Studies consistently identified mild-intensity pain adversely affected adult’s abilities to complete daily activities. Due to the significant heterogeneity of included studies, a meta-analysis was not conducted. Adults with disproportionate short statured SD experience challenges in self-care and domestic tasks, alongside a notable trend that suggests a higher prevalence of pain is linked to increased difficulty in completing daily tasks. Adults with disproportionate short statured skeletal dysplasia (SD) encounter substantial difficulties in self-care and domestic activities, warranting therapists to explore adaptation strategies to better assist individuals dealing with the challenges.Increased pain intensity is associated with greater difficulty in performing these tasks, indicating therapists should explore the impact of pain on a person’s independence.Rehabilitation professionals should routinely evaluate self-care and pain in adults with disproportionate SD using assessment tools tailored to this condition. Adults with disproportionate short statured skeletal dysplasia (SD) encounter substantial difficulties in self-care and domestic activities, warranting therapists to explore adaptation strategies to better assist individuals dealing with the challenges. Increased pain intensity is associated with greater difficulty in performing these tasks, indicating therapists should explore the impact of pain on a person’s independence. Rehabilitation professionals should routinely evaluate self-care and pain in adults with disproportionate SD using assessment tools tailored to this condition.
Terrorism in Central African Republic: A Mosaic of State Fragility and Abnormality
Creators: name: Oko-Otu, Chukwuemeka N.
name: Ani, Kelechi Johnmary
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Religious extremism and radicalization have dominated the discourse on the causes of terrorism. However, little is written of other drivers of terrorism, such as economic and social deprivations, which could prompt religious groups to resort to terrorism. Scholars have sufficiently analyzed the imports of radical ideological and religious views on the emergence of terrorist groups such as Al-Qaida, ISIS, Boko Haram, and Al-Shabaab. By contrast, the Seleka and anti-Balaka terrorists of the Central African Republic introduces a new perspective to the explanation of terrorism. This essay uses the analytical framework of abnormality and State fragility to discuss the rise of terrorism in the Central African Republic. The essay argues that the historical precedent of State failure and weak institutions provides a catalyst that propels the use of terrorism by religious groups, the state and organized groups to demand political and economic dividends as well as a tool for power contestations and regime change. The study recommends multiple peacebuilding and building nation-building processes that will aid the transformation of the state. They include the transformation of the subsistence farming culture to a masses-driven cash crop economy for exportation, which will manage state fragility and promote civil-military counter-terrorism culture at the grassroots. Terrorism is one of the greatest threats to human security and the survival of the state in the 21st century. Since the 9/11 bombings, scholars and policymakers have committed significant resources to unpack the causes and course of terrorism. In this paper, we look away from the prevailing drivers of terrorism such as religious radicalisation and offer another lens through which policymakers and framers of counter-terrorism operations can view the use of terrorism by religious groups, individuals, and non-state actors within a state. The paper argued that where a state is unable to fulfil its social contract with the citizens, such a state permits its citizens to use terrorism as a tool to derive the benefit which the state failed to provide. The paper draws instances from the trajectories of the Balaka and Anti-Seleka terrorist groups operating in the Central Africa Republic.
Lessons Learned about Community-oriented Open Source Software Coordination
Creators: name: Price-Whelan, Adrian M.
Publisher: name: Zenodo
Year: 2022

description: An overview of the Astropy Project, and a few lessons learned about coordinating community software projects. At the "From Data to Software to Science" workshop at the Flatiron Institute. https://indico.flatironinstitute.org/event/2777/
MPEC 2025-H30 : 2025 HF
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 HF

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Studying the Relationship between the Emotional Intelligence and Organizational Citizenship Behavior on Students in Faculty of Management Sciences, Nakhon Pathom Rajabhat University
Creators: name: Woraya Thongun
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University.
Year: 2014
Subjects: The Emotional Intelligence
Organizational Citizenship Behavior

description: Journal of Management Science Nakhon Pathom Rajabhat University, 1, 2, 86-95
Extracellular factors and immunosuppressive drugs influencing insulin secretion of murine islets
Creators: name: Auer, V. J.
name: Janas, E.
name: Ninichuk, V.
name: Eppler, E.
name: Weiss, Thomas S.
name: Kirchner, S.
name: Otto, A. M.
name: Stangl, M. J.
Publisher: name: Universität Regensburg
Year: 2012
Subjects: subject: cytokines, extracellular matrix, IL-1β, immunosuppressive drugs, insulin secretion, islet transplantation, laminin
subject: 610 Medizin

description: Summary

Approximately 60% of transplanted islets undergo apoptosis within the first week post-transplantation into the liver attributed to poor engraftment, immune rejection and toxicity of immunosuppressive drugs. Understanding how extracellular matrix (ECM) components, immunosuppressive drugs and proinflammatory cytokines affect insulin secretion will contribute to an improved clinical outcome of islet transplantations. In this study, functional activity of isolated murine islets was measured by glucose-stimulated insulin secretion (GSIS) and by electrophysiological measurements using patch-clamp. Cultivating islets with soluble fibronectin or laminin, as opposed to with coated laminin, markedly increased GSIS. Addition of cyclosporin A reduced GSIS and suppressed glucose-induced spike activity. Tacrolimus affected neither GSIS nor spike activity, indicating a different mechanism. To evaluate the influence of proinflammatory cytokines, islets were incubated with interleukin (IL)-1β, tumour necrosis factor (TNF)-α or with supernatants from cultured Kupffer cells, the main mediators of inflammation in the hepatic sinusoids. IL-1β exerted a bimodal effect on insulin secretion, stimulating below 2 ng/ml and suppressing above 10 ng/ml. Soluble laminin in combination with a stimulatory IL-1β concentration further increased insulin secretion by 20% compared to IL-1β alone, while with high IL-1β concentrations soluble laminin slightly attenuated GSIS inhibition. TNF-α alone did not affect GSIS, but with stimulatory IL-1β concentrations completely abolished it. Similarly, supernatants derived from Kupffer cells exerted a bimodal effect on GSIS. Our data suggest that improved insulin secretion of transplanted islets could be achieved by including soluble laminin and low IL-1β concentrations in the islet cultivation medium, and by a simultaneous inhibition of cytokine secretion from Kupffer cells.
Guidelines for prepare to career preparation of Silpakorn University students towards Asean Economics Community
Creators: name: Butsakorn Chinthanawat
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University
Year: 2015
Subjects: prepare
Asean Economics Community
Career Preparation
Silpakorn University

description: Journal of Management Science Nakhon Pathom Rajabhat University, 2, 2, 13-30
Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model
Creators: name: Thornton, Sheila J
name: Wong, Ian T
name: Neumann, Rachel
name: Kozlowski, Petri
name: Wasan, Kishor M
Publisher: name: BioMed Central
Year: 2015

description: Previous research indicates that animals fed a high fat (HF) diet supplemented with disodium ascorbyl phytostanyl phosphate (DAPP) exhibit reduced mass accumulation when compared to HF control. This compound is a water-soluble phytostanol ester and consists of a hydrophobic plant stanol covalently bonded to ascorbic acid (Vitamin C). To provide insight into the mechanism of this response, we examined the in vivo effects of a high fat diet supplemented with ascorbic acid (AA) in the presence and absence of unesterified phytosterols (PS), and set out to establish whether the supplements have a synergistic effect in a diet-induced obesity mouse model. Our data indicate that HF diet supplementation with a combination of 1% w/w phytosterol and 1% w/w ascorbic acid results in reduced mass accumulation, with mean differences in absolute mass between PSAA and HF control of 10.05%; and differences in mass accumulation of 21.6% (i.e. the PSAA group gained on average 21% less mass each week from weeks 7-12 than the HF control group). In our previous study, the absolute mass difference between the 2% DAPP and HF control was 41%, while the mean difference in mass accumulation between the two groups for weeks 7-12 was 67.9%. Mass loss was not observed in animals supplemented with PS or AA alone. These data suggest that the supplements are synergistic with respect to mass accumulation, and the esterification of the compounds further potentiates the response. Our data also indicate that chronic administration of PS, both in the presence and absence of AA, results in changes to fecal output and food transit time, providing insight into the possibility of long-term changes in intestinal function related to PS supplementation.
Marketing Mix Affected to Decision Making of Consumer About Optician's Services in Western Region of Thailand
Creators: name: Narasnan Watcharamaneekun
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University
Year: 2015
Subjects: Marketing Mix Consumer's
Decision Making
Eye Glasses Optician's

description: Journal of Management Science Nakhon Pathom Rajabhat University, 2, 2, 31-45
Overexpression and purification of U24 from human herpesvirus type-6 in E. coli: unconventional use of oxidizing environments with a maltose binding protein-hexahistine dual tag to enhance membrane protein yield
Creators: name: Tait, Andrew R.
name: Straus, Suzana
Publisher: name: BioMed Central
Year: 2016

description: Background: Obtaining membrane proteins in sufficient quantity for biophysical study and biotechnological applications has been a difficult task. Use of the maltose binding protein/hexahistidine dual tag system with E.coli as an expression host is emerging as a high throughput method to enhance membrane protein yield, solubility, and purity, but fails to be effective for certain proteins. Optimizing the variables in this system to fine-tune for efficiency can ultimately be a daunting task. To identify factors critical to success in this expression system, we have selected to study U24, a novel membrane protein from Human Herpesvirus type-6 with potent immunosuppressive ability and a possible role in the pathogenesis of the disease multiple sclerosis. Results: We expressed full-length U24 as a C-terminal fusion to a maltose binding protein/hexahistidine tag and examined the effects of temperature, growth medium type, cell strain type, oxidizing vs. reducing conditions and periplasmic vs. cytoplasmic expression location. Temperature appeared to have the greatest effect on yield; at 37°C full-length protein was either poorly expressed (periplasm) or degraded (cytoplasm) whereas at 18°C, expression was improved especially in the periplasm of C41(DE3) cells and in the cytoplasm of oxidizing Δtrx/Δgor mutant strains, Origami 2 and SHuffle. Expression of the fusion protein in these strains were estimated to be 3.2, 5.3 and 4.3 times greater, respectively, compared to commonly-used BL21(DE3) cells. We found that U24 is isolated with an intramolecular disulfide bond under these conditions, and we probed whether this disulfide bond was critical to high yield expression of full-length protein. Expression analysis of a C21SC37S cysteine-free mutant U24 demonstrated that this disulfide was not critical for full-length protein expression, but it is more likely that strained metabolic conditions favour factors which promote protein expression. This hypothesis is supported by the fact that use of minimal media could enhance protein production compared to nutrient-rich LB media. Conclusions: We have found optimal conditions for heterologous expression of U24 from Human Herpesvirus type-6 in E.coli and have demonstrated that milligram quantities of pure protein can be obtained. Strained metabolic conditions such as low temperature, minimal media and an oxidizing environment appeared essential for high-level, full-length protein production and this information may be useful for expressing other membrane proteins of interest.
Local and social media brief No.3: Politics, factions and violence – listening to local voices on Ebola
Creators: name: Sweet, Rachel
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: This brief summarises local media and messages circulating via social media outlets including WhatsApp and local radio and press outlets in the Beni and Butembo areas of North Kivu, DRC between February and April 2019. It also captures the growing number of warning messages and written threats transmitted as part of the escalation of violence against Ebola response teams during this period.
Compilation de données en matière de sciences sociales et comportementales, No.1, Ebola, RDC
Creators: name: Bardosh, Kevin
name: Gercama, Ingrid
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette brève compilation d’analyses de données fournit un « état des lieux » des données en matière de sciences sociales et comportementales liées à la flambée épidémique du virus Ébola dans les provinces du Nord-Kivu et de l’Ituri. Sur la base des données collectées et analysées par des organisations œuvrant au sein de la région, nous avons cherché à examiner les convergences et les divergences entre les ensembles de données et, dans la mesure du possible, les différences par zone géographique, groupe démographique, période de temps et autres variables pertinentes.
Compilation de données en matière de sciences sociales et comportementales, No.3, Ebola, RDC
Creators: name: Bardosh, Kevin
name: Gercama, Ingrid
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette brève compilation d’analyses de données fournit un « état des lieux » des données en matière de science sociale et comportementale liées à la flambée épidémique actuelle du virus Ébola dans les provinces du Nord-Kivu et de l’Ituri. Sur la base des données collectées et analysées par des organisations œuvrant à la riposte au virus Ébola et, de manière plus générale, au sein de la région, elle examine les convergences et les divergences entre les jeux de données. Dans la mesure du possible, cette note prend également en compte les différences dans les données par zone géographique, groupe démographique, période de temps et autres variables pertinentes. Les sources de données sont indiquées à la fin du document. Il s’agit de la troisième compilation d’analyses de données élaborée par la Plateforme Social Science in Humanitarian Action (SSHAP) et elle est axée sur des données générées entre février et mai 2019. Elle est fondée sur les deux notes stratégiques de compilation de données précédentes, dont la première était axée sur des données générées entre août et octobre 2018, et la deuxième sur des données générées entre novembre 2018 et janvier 2019.
The Health Care System in Bolivia
Creators: name: Ledo, Carmen
Publisher: name: Universität Bremen
Year: 2024
Subjects: subject: Bolivia
subject: health
subject: health care
subject: health care system
subject: 300

description: This country report provides a description of the emergence of a health care system under public responsibility in Bolivia. The inception of the health care system refers to the first legislation stipulating entitlements to medical care. The report also includes a brief description of major health care reforms, and the current organization of the health care system in Bolivia. This report is part of the CRC 1342 Social Policy Country Briefs Series.
Emergency Department Utilization Among a Cohort of HIV-Positive Injecting Drug Users in a Canadian Setting
Creators: name: Fairbairn, Nadia
name: Milloy, M-J
name: Zhang, Ruth
name: Lai, Calvin
name: Grafstein, Eric
name: Kerr, Thomas
name: Wood, Evan
Publisher: name: The University of British Columbia
Year: 2017

description: Background HIV-positive injection drug users (IDU) are known to be at risk for multiple medical problems that may necessitate emergency department (ED) use, however, the relative contribution of HIV disease versus injection-related complications have not been well described. Objectives We examined factors associated with ED use among a prospective cohort of HIV-positive IDU in a Canadian setting. Methods We enrolled HIV-positive IDU into a community-recruited prospective cohort study. We modeled factors associated with the time to first ED visit using Cox regression to determine factors independently associated with ED use. In sub-analyses, we examined ED diagnoses and subsequent hospital admission rates. Results Between December 5, 2005, and April 30, 2008, 428 HIV-positive IDU were enrolled, among whom the cumulative incidence of ED use was 63.7% (95% Confidence Interval [CI]: 59.1% – 68.3%) at 12 months after enrollment. Factors independently associated with time to first ED visit included: unstable housing (Hazard Ratio [HR] = 1.5, 95% CI: 1.1–2.0) and reporting being unable to obtain needed health care services (HR = 2.2, 95% CI: 1.2–4.1), whereas CD4 count and viral load were non-significant. Skin and soft tissue infections (SSTIs) accounted for the greatest proportion of ED visits (17%). Of the 2461 visits to the ED, 419 (17%) were admitted to hospital. Conclusions High rates of ED use were observed among HIV-positive IDU, a behavior that was predicted by unstable housing and limited access to primary care. Factors other than HIV infection appear to be driving ED use among this population in the post-HAART era.
Expectation and Quality Perception of the Passengers towards the Bus Service Provision at the Southern Bus Termina
Creators: name: Sunan Nilpuang
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University.
Year: 2014
Subjects: expectation
quality perception
the buses at the southern bus terminal

description: Journal of Management Science Nakhon Pathom Rajabhat University, 1, 2, 96-109
Stabilisierung klassicher, wasserfreier Brönsted-Säuren mittels Lewis-Säuren
Creators: name: Bläsing, Kevin
Publisher: name: Universität Rostock
Year: 2019
Subjects: subject: 540 Chemistry & allied sciences

description: Bei dem Versuch, klassische, wasserfreie Brønsted-Säuren und ihre silylierten Homologe mittels verschiedener Lewis-Säuren zu stabilisieren, gelang es, eine Reihe an neuen Verbindungen herzustellen. Durch die Verwendung der starken und sterisch anspruchsvollen Lewis-Säure B(C6F5)3 konnte zum Beispiel aus flüssigem HCN ein hoch labiles Dimer des Cyanwasserstoffs HCN···HCN−B(C6F5)3 und bei der Verwendung von HN3 das erste HN3-Lewis-Säure-Addukt (HN3−B(C6F5)3) isoliert werden. Die Verwendung des „schweren Protons“ (Me3Si) bei den untersuchten Pseudohalogenen war ebenfalls zielführend.
title: Schule-Eltern-Kommunikation als Haltungsfrage
title: School-Parent-Communication as a Question of Attitude
titleType: AlternativeTitle
Creators: name: Karakaşoğlu, Yasemin
name: Vogel, Dita
Publisher: name: Universität Bremen
Year: 2024
Subjects: subject: Schule
subject: Eltern
subject: Kommunikation
subject: Migration
subject: Mehrsprachigkeit
subject: 370

description: Für eine gelinge Zusammenarbeit zwischen Schule und Eltern ist Kommunikation unerlässlich. In dieser Kommunikation sind Schulen dazu aufgefordert, die vielfältigen Bedürfnisse und Voraussetzungen von Eltern in der Migrationsgesellschaft zu berücksichtigen. Wie dies gelingen kann, stellt sich eher als eine Haltungs- und nicht als Methodenfrage heraus. Zentral sind z.B. frühzeitige und proaktive Kontakte zum Aufbau von gegenseitigem Verständnis, die Anerkennung der Orientierungs- und Informationsfunktion von Schule sowie die Kooperation mit Schlüsselpersonen und -organisationen auch aus migrantischen Communities.
THE EFFECTIVENESS OF ONLINE LANGUAGE LEARNING PROGRAMS FOR PRE-INTERMEDIATE LEVEL STUDENTS
Creators: name: Meliqoʻziyeva, Gulchiroy
name: Musayeva, Zeboxon
Publisher: name: Zenodo
Year: 2024

description: In recent years, the use of online language learning programs has become increasingly popular among students at all levels. This article examines the effectiveness of these programs specifically for pre-intermediate level students. It will explore the advantages and disadvantages of online language learning, as well as the impact of these programs on students' language proficiency and motivation. Additionally, this article will review scholarly research on the topic and provide recommendations for educators and learners.
Improving Outcomes in Cardiogenic Shock Through Enhanced Systems of Care and Hemodynamic Support Strategies
Creators: name: Bloom, Jason Elliott
Publisher: name: Monash University
Year: 2025
Subjects: classificationCode: 320101
subject: Cardiology (incl. cardiovascular diseases)

description: Cardiogenic shock (CS) is a clinical syndrome characterised by cardiac dysfunction and
consequent end-organ hypoperfusion in the presence of normal or elevated cardiac filling
pressures. Despite advances in the interventions available for use in this cohort
of patients, there remains an unacceptably high-risk of significant morbidity, and both short and
long-term mortality. This thesis seeks to explore these fundamental aspects of CS management through two key domains of study; first, a series of studies assessing the epidemillogy and outcomes of cardiogenic shock; and, the second domain of study has focused on the hemodynamic support strategies utilized for patients with CS.
Mutations in gyrA and parC Genes in Quinolone-Resistant Klebsiella pneumoniae Isolates from Borujerd Hospitals
Creators: name: Journal Of Advances In Medical And Biomedical Research
name: Shokoohizadeh, Leili
name: Saniee, Mehrangiz
name: Mirzaee, Mohsen
name: Taheri, Mohammad
Publisher: name: figshare
Year: 2020
Subjects: subject: 110899 Medical Microbiology not elsewhere classified
subject: FOS: Health sciences

description: Background and Objective: Quinolones are the antibiotics used to treat infections. Several reports have indicated the increased resistance to quinolone in K. pneumoniae strains all over the world. The aim of this study is to investigate amino acid substitutions in GyrA and ParC proteins among quinolone-resistant isolates of K. pneumoniae in Borujerd )west of Iran( hospitals.
Materials and Methods: Totally, 100 isolates of K. pneumoniae were collected. After validating the isolates by conventional laboratory methods, an antimicrobial susceptibility test was carried out for some antibiotics from the quinolones family. Quinolone resistance and Minimum Inhibitory Concentration (MIC) of Ciprofloxacin were detected by disk diffusion and E-test methods, respectively. The amplification of gyrA and parC genes in quinolone-resistant strains was performed by PCR using specific primers. PCR products were sequenced in order to detect the mutations in gyrA and parC genes.
Results: Generally, 38% of all the collected isolates were resistant to Nalidixic acid and Ciprofloxacin, 18% were resistant to Ofloxacin, and 15% were resistant to Norfloxacin. Concurrent resistance to Nalidixic acid, Ciprofloxacin, Ofloxacin, and Norfloxacin was determined in 15% of the cases. In 86% (n=20) of Ciprofloxacin-resistant strains, MIC was measured 128 μg/mL. The mutation rate was 40% (n=9) in gyrA gene in quinolone-resistant strains and 35% (n=8) in parC gene.
Open Data Management Plan (Update)
Creators: name: Santucci Raffaella
name: Grillo Vincenzo
name: Gazzadi Gian Carlo
Publisher: name: Zenodo
Year: 2020
Subjects: Q-sort

description: The Europe 2020 strategy for a smart, sustainable, and inclusive economy underlines the central role of
 knowledge and innovation in generating growth. For this reason, the European Union strives to improve
 access to scientific information and to boost the benefits of public investment in the research funded under
 the EU Framework Programme for Research and Innovation Horizon 2020 (2014-2020).
 According to this strategy, in Horizon 2020 a limited pilot action on open access to research data has been
 implemented so that participating projects will be required to develop an Open Data Management Plan
 (ODMP), in which they will specify what data will be open.
 This updated version of the deliverable of the Q-SORT project is prepared as part of WP1, Open Data
 Management Plan (Update). In this document we update the discussion regarding the management, life
 cycle, processes of data generated by Q-SORT in order to make such data findable, accessible,
 interoperable, and reusable (FAIR).
 The aim of this document is to provide an analysis of the main elements of the data management policy
 that will be used with regard to all the data sets that will be generated by the project.
 In particular, the deliverable outlines how research data will be handled during the lifetime of Q-SORT and
 describes what data will be collected, processed or generated and what methodology will be followed,
 whether and how this data will be shared and/or made open, and how it will be curated and preserved.
 This data management plan is intended as a dynamic document that will be edited and updated during the
 project.
Social and local media brief No.2: Media and local messages on Ebola in the Grand Nord, DRC
Creators: name: Sweet, Rachel
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: This note provides an overview of a selection of key messages related to the Ebola outbreak and response that were circulating on WhatsApp and in the local media in the Grand Nord (Beni and Lubero territories), DRC, in November and December 2018.
НЕКОТОРЫЕ ОСОБЕННОСТИ ПРИВЛЕЧЕНИЯ К ОТВЕТСТВЕННОСТИ ЗА ЗЛОУПОТРЕБЛЕНИЕ ДОЛЖНОСТНЫМИ ПОЛНОМОЧИЯМИ НА ОСНОВЕ АНАЛИЗА ЗАКОНОДАТЕЛЬСТВА РЕСПУБЛИКИ УЗБЕКИСТАН
Creators: name: Тохиржонов Шерзод Шухратжон ўғли
Publisher: name: Zenodo
Year: 2024

description: Аннотация: в данном тезисе проводится научно-теоретический анализ понятия злоупотребления должностными полномочиями, кроме того обсуждено объективные и субъективные стороны данного преступления. Следовательно, даны решения и предложения совершенствования уголовной ответственности за злоупотребления должностными полномочиями.

Ключевые слова: уголовное право, ответственность, злоупотребления должностными полномочиями, противодействие коррупции, должностное лицо,
Bulletin d’informations médias locaux #3: Politique, dissensions et violence - à l’écoute des porte-paroles locaux s’exprimant au sujet d’Ébola, RDC
Creators: name: Sweet, Rachel
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette note stratégique résume les médias locaux et les messages ayant circulé sur les médias sociaux, y compris sur WhatsApp, à la radio locale et à travers les organes de presse dans les régions de Beni et Butembo de la province du Nord-Kivu, RDC, entre février et avril 2019. Elle rend également compte du nombre croissant de messages de mise en garde et de lettres de menaces transmis dans le cadre de l’escalade de violence à l’encontre des équipes de riposte contre le virus Ébola au cours de cette période.
Supplementary document for Miniaturized high-efficiency snapshot polarimetric stereoscopic imaging - 7377855.pdf
Creators: name: Fu, Boyan
name: Zhou, Xuxi
name: Li, Tianyue
name: Zhu, Hao
name: Liu, Zhen
name: Zheng, Shiyu
name: Zhou, Yifan
name: Yu, Yiwan
name: Cao, Xun
name: Wang, Shuming
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Applied Physics

description: Supplemental Document
Compilation de données en matière de sciences sociales et comportementales, No.2, Ebola, RDC
Creators: name: Bardosh Kevin
name: Gercama, Ingrid
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette brève compilation d’analyses de données fournit un « état des lieux » des données en matière de sciences sociales et comportementales liées à la flambée épidémique actuelle du virus Ébola dans les provinces du Nord-Kivu et de l’Ituri. Sur la base des données collectées et analysées par des organisations œuvrant à la riposte au virus Ébola et, de manière plus générale, au sein de la région, elle examine les convergences et les divergences entre les ensembles de données et, dans la mesure du possible, les différences par zone géographique, groupe démographique, période de temps et autres variables pertinentes. Les sources de données sont indiquées à la fin du document.
Cette note stratégique est axée sur les données générées entre novembre 2018 et début février 2019, et inclut également des études réalisées au mois d’octobre, mais seulement mises à disposition pour analyse en novembre 2018. Elle est fondée sur une précédente note stratégique de compilation de données de la SSHAP qui faisait la synthèse des données en matière de sciences sociales et comportementales générées entre août et octobre 2018.
Considérations clés : Préparation et planification de riposte contre le virus Ébola à Goma, RDC
Creators: name: Peyton, David
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette note stratégique résume les considérations clés inhérentes au contexte social, politique et économique de Goma dans le contexte de la flambée épidémique d’Ébola survenue en RDC en mars 2019. Goma est la capitale administrative de la province du Nord-Kivu et un centre urbain majeur dans la région des Grands Lacs. La ville compte environ 1,5 million d’habitants et constitue un important centre économique et de transport qui relie l’est du Congo à l’ensemble des sous-régions d’Afrique de l’Est. L’apparition du virus Ébola à Goma augmenterait sensiblement la population à risque et contribuerait à renforcer le potentiel de transmission transfrontalière aux pays limitrophes, notamment le Rwanda. Par conséquent, cette note stratégique est axée sur les structures sociales et politiques locales qui peuvent être exploitées afin de promouvoir des actions de préparation et de planification.
Considérations clés : évolution des comportements & des pratiques en matière de recours aux services de santé dans le Grand Nord de la province du Nord-Kivu, en RDC
Creators: name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette note stratégique résume les considérations clés relatives aux évolutions des comportements et des pratiques en matière de recours aux services de santé dans le contexte de la flambée épidémique d’Ébola survenue dans le Grand Nord de la province du Nord-Kivu, en RDC, en septembre 2018. D’autres enquêtes participatives doivent être menées auprès des populations touchées, mais étant donné la transmission actuelle du virus, communiquer sur les considérations clés et des recommandations immédiates a été jugé prioritaire.
interTwin D3.5 DTE Blueprint Architecture, Functional Specifications, and Requirements Analysis, third version
Creators: name: Bardaji, Raul
name: Manzi, Andrea
name: Rodero, Ivan
name: Geened, Thomas
name: Warde, Adam
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Architecture
subject: FOS: Civil engineering
subject: functional specifications
subject: requirements analysis
subject: Digital Twin Engine

description: This document presents the last architectural blueprint for the interTwin Digital Twin Engine (DTE), detailing its functional specifications, requirements analysis, and components. The blueprint guides the technical Work Packages (WPs) within the interTwin project, ensuring alignment with associated subsystem requirements. Furthermore, it integrates insights from related initiatives and projects to identify architectural components that can be adopted within the interTwin framework. This blueprint acts as the definitive conceptual model for the DTE.
Compilation de données en matière de science sociale et comportementale, No.4, Ebola, RDC
Creators: name: Bardosh, Kevin
name: Jones, Theresa
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette brève compilation d’analyses de données fournit un « état des lieux » des données en matière de science sociale et comportementale liées à la flambée épidémique actuelle du virus Ébola dans les provinces du Nord-Kivu et de l’Ituri. Sur la base des données collectées et analysées par des organisations œuvrant à la riposte au virus Ébola et, de manière plus générale, au sein de la région, elle examine les convergences et les divergences entre les ensembles de données. Dans la mesure du possible, cette note prend également en compte les différences dans les données par zone géographique, groupe démographique, période de temps et autres variables pertinentes. Les sources de données sont indiquées à la fin du document. Il s’agit de la quatrième compilation d’analyses de données élaborée par la Plateforme Social Science in Humanitarian Action (SSHAP) et elle est axée sur des données générées entre juin et août 2019. Elle est fondée sur les trois notes stratégiques de compilation de données précédentes, dont la première était axée sur des données générées entre août et octobre 2018, la deuxième sur des données générées entre novembre 2018 et janvier 2019, et la troisième sur des données générées entre février et mai 2019.
Transient laboratory X-ray absorption fine structure spectroscopy on thin films demonstrated with F8BT
Creators: name: Jonas, Adrian
name: Witte, Katharina
name: Kanngießer, Birgit
name: Stiel, Holger
name: Mantouvalou, Ioanna
Publisher: name: Technische Universität Berlin
Year: 2021
Subjects: subject: 530 Physik
subject: laboratory XAFS
subject: soft X-rays
subject: pump-probe spectroscopy
subject: transient NEXAFS
subject: F8BT

description: We present advanced instrumentation for the investigation of thin organic films offered by a laboratory X-ray absorption fine structure (XAFS) spectrometer for the soft X-ray range. The transmission spectrometer is based on a laser-produced plasma source in combination with a twin-arm reflection zone plate spectrometer. The efficiency and stability of the spectrometer allow for single shot measurements within 500 ps with a resolving power of E/ΔE ~ 900 in a range between 200 eV and 1300 eV. Through the implementation of an optical pump beam, also transient absorption measurements can be performed. The merits of the spectrometer are demonstrated through the investigation of poly[(9,9-dioctylfluorenyl- 2,7-diyl)-alt-co-(1,4-benzo-{2,1‘,3}-thiadiazole)] (F8BT), a polyfluorene copolymer. Transient optical pump soft X-ray probe spectroscopy with 500 ps time resolution detects changes in the C K edge spectrum which can be attributed to the lowest unoccupied molecular orbitals of the molecules in the benzothiadiazole unit.
Dynamique transfrontalière et services de santé dans la région du Nil occidental, Ouganda
Creators: name: Storer, Elizabeth
name: Pearson, Georgina
name: Bedford, Juliet
name: Socia Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Dans le contexte du travail de préparation réalisé en Ouganda en rapport avec la flambée épidémique d’Ébola survenue en RDC, cette note stratégique résume les considérations clés inhérentes à la dynamique transfrontalière, aux structures de santé et aux comportements au sein de la sous-région du Nil occidental du nord-ouest de l’Ouganda.
Dynamique transfrontalière Ouganda-RDC
Creators: name: Bedford, Juliet
name: Akello, Grace
name: Gercama, Ingrid
name: Jones, Theresa
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette note stratégique résume les considérations clés relatives à la dynamique transfrontalière entre l’Ouganda et la République démocratique du Congo (RDC) dans le contexte de la flambée épidémique d’Ébola survenue dans le Nord-Kivu et dans les provinces environnantes, en décembre 2018. D’autres enquêtes participatives doivent être menées auprès des populations touchées, mais au vu de la dynamique épidémique actuelle, la priorité a été accordée à la communication des considérations clés et des recommandations immédiates relatives à la participation communautaire.
Proliferation Resistance Analysis of Offshore Floating Nuclear Power Plant: Extended Materials from IZES 2023
Creators: name: Hara, Daisuke
Publisher: name: Daisuke Hara
Year: 2025

description: This Zenodo record contains both the conference paper and presentation slides presented at the 2023 International Symposium on Zero-Carbon Energy Systems (IZES). The paper is published as Open Access in "Progress in Nuclear Science and Technology", while the presentation slides were originally shared during the conference and are now made publicly available.

Title: Proliferation Resistance Analysis of Offshore Floating Nuclear Power Plant (OFNP)Authors: Daisuke Hara, Hiroshi SagaraPresented: January 11, 2023Published Paper: https://doi.org/10.15669/pnst.7.324

本記録は、2023年1月に開催された国際会議IZESにて発表された論文および発表スライドをまとめたものです。
Direito da População LGBTQIA+
Creators: name: Silva-Júnior, Wellington Fernando da
name: Revoredo, Liliane
name: Monart, Dan
name: Laura, Marina
name: Silva, Giseli Maria
name: Lima Menezes, Luana
name: Bezerra da Silva, Renata kelly
name: Silva, Orlando
Publisher: name: Zenodo
Year: 2025

description: O presente estudo emergiu da seguinte arguição: quais são os direitos da população LGBTQIA+ no Brasil e qual o entendimento jurisprudencial sobre a matéria em questão? E com isso objetivou descrever sistematicamente os direitos da população LGBTQIA+ no Brasil, considerando a Constituição Federal e o entendimento jurisprudencial sobre o assunto. Para tanto, foram analisados julgamentos do Supremo Tribunal Federal (STF) e do Superior Tribunal de Justiça (STJ), bem como acórdãos de Tribunais Regionais e a legislação vigente, sobretudo a Constituição Federal. A pesquisa, de natureza documental e explicativa, utilizou bases de dados jurídicas e artigos acadêmicos para compilar os direitos inerentes à comunidade LGBTQIA+. Embora a legislação brasileira assegure direitos fundamentais como igualdade, liberdade e segurança, a população LGBTQIA+ ainda enfrenta desafios significativos, como a violência e a discriminação sistemática. Julgados recentes demonstram avanços na proteção jurídica, como o reconhecimento da união estável homoafetiva, criminalização da homofobia e transgeneridade como questão de identidade pessoal, direito à saúde e respeito no ambiente de trabalho. A análise demonstra que, apesar do progresso normativo e jurisprudencial, há uma deficiência na efetivação dos direitos dessa população, demandando maior compromisso do Poder Público. Assim, o estudo reforça a necessidade de maior conscientização e instrumentalização jurídica para garantir a proteção e inclusão da população LGBTQIA+ na sociedade brasileira.
title: Guzmania :
title: Principes directeurs pour la conduite de l’examen de la distinction, de l’homogénéité et de la stabilité.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Group identity.
New Varieties of Plants
Guzmania

description: Ces principes directeurs (“principes directeurs d’examen”) visent à approfondir les principes énoncés dans l’introduction générale (document TG/1/3) et dans les documents TGP qui s’y rapportent afin de donner des indications concrètes détaillées pour l’harmonisation de l’examen de la distinction, de l’homogénéité et de la stabilité (DHS) et, en particulier, à identifier des caractères convenant à l’examen DHS et à la production de descriptions variétales harmonisées.
Dynamiques transfrontalières entre le Soudan du Sud et la RDC
Creators: name: Pendle, Naomi
name: Marko, Ferenc David
name: Gercama, Ingrid
name: Bedford, Juliet
name: Social Science In Humanitarian Action Platform
Publisher: name: F1000 Research Limited
Year: 2020

description: Cette note stratégique résume les considérations clés liées aux dynamiques transfrontalières entre le Soudan du Sud et la République démocratique du Congo (RDC) dans le contexte de la flambée épidémique d’Ébola survenue dans le Nord-Kivu et les provinces environnantes.