cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Quinolizidines as Novel SARS-CoV-2 Entry Inhibitors
Creators: name: Rana, Tanu
name: Goodwin, Jeffery Shawn
name: Chen, Chin-Ho
name: Xie, Hua
name: Huang, Li
name: Xie, Lan
name: Zhu, Lei
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: COVID-19, caused by the highly transmissible severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has rapidly spread and become a pandemic since its outbreak in 2019. We have previously discovered that aloperine is a new privileged scaffold that can be modified to become a specific antiviral compound with markedly improved potency against different viruses, such as the influenza virus. In this study, we have identified a collection of aloperine derivatives that can inhibit the entry of SARS-CoV-2 into host cells. Compound 5 is the most potent tested aloperine derivative that inhibited the entry of SARS-CoV-2 (D614G variant) spike protein-pseudotyped virus with an IC50 of 0.5 µM. The compound was also active against several other SARS-CoV-2 variants including Delta and Omicron. Results of a confocal microscopy study suggest that compound 5 inhibited the viral entry before fusion to the cell or endosomal membrane. The results are consistent with the notion that aloperine is a privileged scaffold that can be used to develop potent anti-SARS-CoV-2 entry inhibitors.
Responding to stakeholder needs to engage rehabilitation professionals in the delivery of evidence-based health programming for adults with osteoarthritis
Creators: name: Weisner, Serena
name: Chevan, Julia
name: Pappas, Kathleen
name: Barrett, Maureen
name: Nowakowski, Kimberly
name: Erck, Elizabeth
name: Murphy, Heather
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Although there are many evidence-based programs that promote healthy lifestyles and symptom modification for people with osteoarthritis, their delivery in rehabilitation clinical settings in the United States is limited. These programs can be a primary component of treatment or a discharge option to facilitate long-term mobility and pain management. The purpose of this perspective article is to describe a delivery model that brings one arthritis-appropriate, evidence-based intervention, the Arthritis Foundation's Walk With Ease program, to older adults seeking physical therapy related to their osteoarthritis. We embedded program delivery into a Doctor of Physical Therapy curriculum using a student health coaching approach and partnering with physical therapy clinics and other community agencies for participant referrals. This model of delivery is cost-effective, sustainable, and provides outcomes that meet goals of the national agenda for osteoarthritis. The model provides benefits for students in health professions education programs, community organizations and rehabilitation clinics, and adults living with osteoarthritis.
Additional file 34 of Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales
Creators: name: Rassbach, Johannes
name: Hilsberg, Nathalie
name: Haensch, Veit G.
name: Dörner, Sebastian
name: Gressler, Julia
name: Sonnabend, Robin
name: Semm, Caroline
name: Voigt, Kerstin
name: Hertweck, Christian
name: Gressler, Markus
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Organic Chemistry
subject: FOS: Chemical sciences

description: Additional file 34: Figure S30. Determination of the optimal reaction conditions for LinA.
Roles of $a_0(980)$, $Λ(1670)$, and $Σ(1385)$ in the $Λ_c^+ \to ηΛπ^+$ decay
Creators: name: Wang, Guan-Ying
name: Wei, Neng-Chang
name: Yang, Hui-Min
name: Wang, En
name: Geng, Li-Sheng
name: Xie, Ju-Jun
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recently, the Belle Collaboration has measured the $Λ_c^+ \to ηΛπ^+$ decay and reported the $ηΛ$ and $Λπ^+ $ invariant mass distributions, which show the clear signals of the resonances $Λ(1670)$ and $Σ(1385)$, respectively. Based on our previous works [Eur. Phys. J. C 76 (2016) 496 and Phys. Rev. D 95 (2017) 074024], we re-analyze this process by considering the $S$-wave $ηΛ$ and $ηπ^+$ final state interactions within the chiral unitary approach, which dynamically generate the $Λ(1670)$ and $a_0(980)$, respectively. Our results are in good agreement with the Belle measurements, which supports the molecular nature of the $Λ(1670)$ and $a_0(980)$. In addition, the $ηπ^+$ invariant mass distributions are also computed and a cusp structure of $a_0(980)$ is cleary shown around the $K\bar{K}$ mass threshold.
description: 8 pages, 9 figures
Effects of Flattery in Obtaining Compliance
Creators: name: Goodall, Jill
name: Ilustre, Irma
name: Marquis, Catherine
name: Nicolella, Nicholas
name: Sikaitis, Joline
Publisher: name: Figshare
Year: 2018
Subjects: subject: 170113 Social and Community Psychology
subject: FOS: Psychology

description: This research investigated the relationship of flattery in obtaining compliance. Thirty male and thirty female students from Carnegie Mellon University were approached by a confederate of the opposite gender and asked to complete a one-page questionnaire. Afterwards, the confederates either flattered the participant using specific or non-specific flattery or did not flatter the participants at all. These assignments were random and the confederate had no knowledge of the treatment prior to approaching the participant. The confederate then asked the participant to complete a five-page questionnaire. We hypothesized that the most compliance would be obtained in the specific flattery condition, followed by the non-specific flattery condition, with the no flattery condition eliciting the least compliance. Our findings supported this hypothesis. We also examined whether women showed more compliance than men across all conditions. Our results indicated that women did show more compliance but only for the two types of flattery conditions. The implications of this study can be applied to areas where flattery would be helpful in obtaining compliance such as in advertising, sales and politics.There are many situations in life in when people are able to convince a person or even an entire group to comply with their wishes. These situations are probably most apparent in the sales industry, advertising industry, and political realm. It is conceivable that in these situations, flattery was used to gain compliance. It is important to research and test this social phenomenon because the findings can be highly relevant not only in the advertising and sales industries and the political realm, but also on a basic level of interactions between people on a daily basis.
Witnessing the transformation of a quasar host galaxy at z=1.6
Creators: name: Humphrey, A.
name: Roche, N.
name: Gomes, J. M.
name: Papaderos, P.
name: Villar-Martín, M.
name: Filho, M. E.
name: Emonts, B. H. C.
name: Aretxaga, I.
name: Binette, L.
name: Flaquer, B. Ocaña
name: Lagos, P.
name: Torrealba, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: A significant minority of high redshift radio galaxy (HzRG) candidates show extremely red broad band colours and remain undetected in emission lines after optical `discovery' spectroscopy. In this paper we present deep GTC optical imaging and spectroscopy of one such radio galaxy, 5C 7.245, with the aim of better understanding the nature of these enigmatic objects. Our g-band image shows no significant emission coincident with the stellar emission of the host galaxy, but does reveal faint emission offset by ~3" (26 kpc) therefrom along a similar position angle to that of the radio jets, reminiscent of the `alignment effect' often seen in the optically luminous HzRGs. This offset g-band source is also detected in several UV emission lines, giving it a redshift of 1.609, with emission line flux ratios inconsistent with photoionization by young stars or an AGN, but consistent with ionization by fast shocks. Based on its unusual gas geometry, we argue that in 5C 7.245 we are witnessing a rare (or rarely observed) phase in the evolution of quasar hosts when stellar mass assembly, accretion onto the back hole, and powerful feedback activity has eradicated its cold gas from the central ~20 kpc, but is still in the process of cleansing cold gas from its extended halo.
description: Accepted for publication in MNRAS
Adeno-associated virus-mediated expression of activated factor V (FVa) for hemophilia phenotypic correction
Creators: name: Nichols, Timothy C.
name: Dobbins, Amanda L.
name: Niu, Hongqian
name: Sun, Junjiang
name: Chai, Zheng
name: Li, Chengwen
name: Chen, Xiaojing
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Adeno-associated virus (AAV) gene therapy has been successfully applied in hemophilia patients excluding patients with inhibitors. During the coagulation pathway, activated factor V (FVa) functions downstream as a cofactor of activated factor X (FXa) to amplify thrombin generation. We hypothesize that the expression of FVa via gene therapy can improve hemostasis of both factor IX and FVIII deficiencies, regardless of clotting factor inhibitor. A human FVa (hFVa) expression cassette was constructed, and AAV8 vectors encoding hFVa (AAV8/TTR-hFVa) were intravenously administrated into mice with hemophilia A and B with or without FVIII inhibitors. Hemostasis, including hFVa level, activated partial thromboplastin time (aPTT), tail clip, and the saphenous vein bleeding assay (SVBA), was evaluated. In hemophilia B mice, a dose of 4 × 1013 vg/kg AAV8/TTR-hFVa vectors achieved a complete phenotypic correction over 28 weeks. In hemophilia A mice, hemostasis improvement was also achieved, regardless of FVIII inhibitor development. In vivo hemostasis efficacy was confirmed by tail clip and SVBA. Interestingly, while minimal shortening of aPTT was observed at a lower dose of AAV8 vectors, hemostasis improvement was still achieved via in vivo bleeding assays. Collectively, FVa-based AAV gene therapy shows promise for hemostasis correction in hemophilia, regardless of inhibitor development and no potential risk for thrombosis.
Evolution of the Milky Way with radial motions of stars and gas II. The evolution of abundance profiles from H to Ni
Creators: name: Kubryk, M.
name: Prantzos, N.
name: Athanassoula, E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We study the role of radial motions of stars and gas on the evolution of abundance profiles in the Milky Way disk. We investigate, in a parametrized way, the impact of radial flows of gas and radial migration of stars induced mainly by the Galactic bar and its iteraction with the spiral arms. We use a model with several new or up-dated ingredients (atomic and molecular gas phases, star formation depending on molecular gas, recent sets of metallicity-dependent stellar yields from H to Ni, observationally inferred SNIa rates), which reproduces well most global and local observables of the Milky Way. We obtain abundance profiles flattening both in the inner disk (because of radial flows) and in the outer disk (because of the adopted star formation law). The gas abundance profiles flatten with time, but the corresponding stellar profiles appear to be steeper for younger stars, because of radial migration. We find a correlation between the stellar abundance profiles and O/Fe, which is a proxy for stellar age. Our final abundance profiles are in overall agreement with observations, but slightly steeper (by 0.01-0.02 dex/kpc) for elements above S. We find an interesting "odd-even effect" in the behaviour of the abundance profiles (steeper slopes for odd elements) for all sets of stellar yields; however, this behaviour does not appear in observations, suggesting that the effect is, perhaps, overestimated in current stellar nucleosynthesis calculations.
description: 16 pages, 11 figures, accepted in Astronomy and Astrophysics
A low-mass hub-filament with double centre revealed in NGC2071-North
Creators: name: Könyves, Vera
name: Ward-Thompson, Derek
name: Shimajiri, Yoshito
name: Palmeirim, Pedro
name: André, Philippe
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present the first analysis in NGC2071-North as a resolved hub-filament featuring a double centre. This $\sim 1.5 \times 1.5$ parsec-scale filament hub contains $\sim$500 $M_\odot$. Seen from Planck, magnetic field lines may have facilitated the gathering of material at this isolated location. The energy balance analysis, supported by infalling gas signatures, reveal that these filaments are currently forming stars. Herschel 100 $μ$m emission concentrates in the hub, at IRAS 05451+0037 and LkH$α$ 316, and presents diffuse lobes and loops around them. We suggest that such a double centre could be formed, because the converging locations of filament pairs are offset, by 2.3$'$ (0.27 pc). This distance also matches the diameter of a hub-ring, seen in column density and molecular tracers, such as HCO$^+$(1$-$0) and HCN(1$-$0), that may indicate a transition and the connection between the hub and the radiating filaments. We argue that all of the three components of the emission star LkH$α$ 316 are in physical association. We find that a $\sim$0.06 pc-sized gas loop, attached to IRAS 05451+0037, can be seen at wavelengths all the way from Pan-STARRS-i to Herschel-100 $μ$m. These observations suggest that both protostars at the double hub centre are interacting with the cloud material. In our $^{13}$CO data, we do not seem to find the outflow of this region that was identified in the 80s with much lower resolution.
description: 18 pages, 12 figures, accepted for publication in the MNRAS
The Overview of Hubei Academic Digital Library
Creators: name: Zhengguo, Hong
Publisher: name: Figshare
Year: 2018
Subjects: subject: 80706 Librarianship
subject: FOS: Media and communications

description: This paper briefly introduced the Hubei Academic Digital Library(HBDLIB) . HBDLIB includes over 100 universities and colleges. The system includes 2 data center: Wuhan University and Huazhong University of  Science and Technology. The system provides shared storage disk system to store many colleges’ resource and mirror of many databases. The hbdlib connect to internet through CERNet and ChinaNet. The system provides document delivery service for over 100 colleges of Hubei. The portal website provides uniform-search of many databases and OPAC of 10 main universities. The website also provides the navigation of resource of many colleges.
Dorado and its member galaxies. III. Mapping star formation with FUV imaging from UVIT
Creators: name: Rampazzo, R.
name: Mazzei, P.
name: Marino, A.
name: Bianchi, L.
name: Postma, J.
name: Ragusa, R.
name: Spavone, M.
name: Iodice, E.
name: Ciroi, S.
name: Held, E. V.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We are investigating the SF in galaxies of the actively evolving Dorado group where signatures of interactions and merging events are revealed by optical and radio observations in both ETGs and LTGs. Our previous Ha+[NII] study, probing ~10 Myrs timescales, suggested that SF is still ongoing in ETGs. In this work, we use far-UV (FUV) imaging to map recent SF on times scales of about 100 Myrs. We used the Ultraviolet telescope UVIT on board Astrosat to image the Dorado backbone galaxies previously observed in Ha+[NII], with the far-UV filter FUV.CaF2 (1300-1800A). The sample includes NGC1536, NGC1546, NGC1549, [CMI2001]4136-01, NGC1553, IC2058, PGC75125,NGC1566, NGC1596 and NGC1602. FUV.CaF2 emission is revealed in all galaxies, tracing young stellar populations in rings and showing tidal distortions. The Sersic index, derived by fitting the luminosity profiles, is always n<3 suggesting that the FUV.CaF2 emission originates from a disk also in ETGs. The SFR ranges from 0.004+-0.001 M_sol yr^{-1} of [CMI2001]4136-01 to 2.455+-0.027 M_sol yr^{-1} of NGC 1566. Most of the recent SF is found at the periphery of the Dorado group where most of LTGs are located. For these galaxies, the ratio SFR_Ha/SFR_FUV.CaF2 is close to 1, except for the edge-on IC 2058, similarly to previously reported relations for Local Volume samples. For ETGs, however, SFR_Ha is about 15 times higher than SFR_FUV. The Dorado's ETGs define a separate locus in SFR_FUV, SFR_Ha space with respect to the LTGs, which is well represented by the relation log (SFR_FUV.CaF2) = 0.70xlog (SFR_{Ha})-1.26.The disk structure of the FUV.CaF2 emitting populations discovered in all the ETGs implies dissipative processes and wet merging events. The systematic discrepancy between SFRs derived from Ha and FUV fluxes suggests that rejuvenation episodes in ETGs cannot sustain constant SF over ~100 Myrs timescales.
description: 20 pages, 16 figures, accepted for publication in Astronomy & Astrophysics Main Journal
2DOF External Fixator and Computer-Assisted Surgical System for 6DOF Orthopedic Correction Using Axis-Angle Representation
Creators: name: Wu, Ying Ying
Publisher: name: Figshare
Year: 2018
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: Orthopedic deformities are often complex three-dimensional (3D) deformities, and the reconstruction of the original or normal geometry is difficult. In this thesis, the use of external fixators were investigate for long bone deformity correction and clubfoot correction. An external fixator works by attaching to bones or bone fragments and moving them to the target geometry. Its key advantages are that it encourages tissue growth and preserves healthy tissues. However, current six degrees of freedom (6DOF) external fixators are difficult to set up, resulting in long surgeries and steep learning curves for surgeons. They are also bulky and obstruct patient mobility. The integration of computational methods and surgical assistive device to the surgery to improve the accuracy of external fixation was proposed. A new method of defining orthopedic deformity correction was developed, and the 6DOF correction problem was reduced to just 2DOF using axis-angle representation. Therefore, only two physical trajectory joints are needed so the fixator can be more compact. The planner minimizes the bulk of the external fixator, and optimizes the distraction schedule to avoid overstretching the soft tissues. The surgical assistive device is a passive positioning linkage that assists the surgeon in building an accurate external fixator that can achieve complete correction. It is not actuated but has brakes to hold its end effector pose. The planner and linkage is expected to reduce the learning curve for surgeons and shorten surgery time. To validate the system, a patient-specific clubfoot model was developed. This model has a 3D printed rigid skeletal structure with an outer layer of gel that mimics human muscles. Thus, it can support bone pin insertions while still maintaining the flexibility to demonstrate the correction. Four experiments were performed on the foot model. The accuracy of midfoot correction was 11 mm and 3.5 deg without loading, and 41 mm and 11.7 deg with loading. While the external fixator has to be more rigid to overcome resistance against correction, the surgical system itself was able to achieve accurate correction in less than two hours. This is an improvement from the current method which takes 2.5 to 4.5 hours.
Massive stars exploding in a He-rich circumstellar medium. V. Observations of the slow-evolving SN Ibn OGLE-2012-SN-006
Creators: name: Pastorello, A.
name: Wyrzykowski, L.
name: Valenti, S.
name: Prieto, J. L.
name: Kozlowski, S.
name: Udalski, A.
name: Elias-Rosa, N.
name: Morales-Garoffolo, A.
name: Anderson, J. P.
name: Benetti, S.
name: Bersten, M.
name: Botticella, M. T.
name: Cappellaro, E.
name: Fasano, G.
name: Fraser, M.
name: Gal-Yam, A.
name: Gillone, M.
name: Graham, M. L.
name: Greiner, J.
name: Hachinger, S.
name: Howell, D. A.
name: Inserra, C.
name: Parrent, J.
name: Rau, A.
name: Schulze, S.
name: Smartt, S. J.
name: Smith, K. W.
name: Turatto, M.
name: Yaron, O.
name: Young, D. R.
name: Kubiak, M.
name: Szymanski, M. K.
name: Pietrzynski, G.
name: Soszynski, I.
name: Ulaczyk, K.
name: Poleski, R.
name: Pietrukowicz, P.
name: Skowron, J.
name: Mroz, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present optical observations of the peculiar Type Ibn supernova (SN Ibn) OGLE-2012-SN-006, discovered and monitored by the OGLE-IV survey, and spectroscopically followed by PESSTO at late phases. Stringent pre-discovery limits constrain the explosion epoch with fair precision to JD = 2456203.8 +- 4.0. The rise time to the I-band light curve maximum is about two weeks. The object reaches the peak absolute magnitude M(I) = -19.65 +- 0.19 on JD = 2456218.1 +- 1.8. After maximum, the light curve declines for about 25 days with a rate of 4 mag per 100d. The symmetric I-band peak resembles that of canonical Type Ib/c supernovae (SNe), whereas SNe Ibn usually exhibit asymmetric and narrower early-time light curves. Since 25 days past maximum, the light curve flattens with a decline rate slower than that of the 56Co to 56Fe decay, although at very late phases it steepens to approach that rate. An early-time spectrum is dominated by a blue continuum, with only a marginal evidence for the presence of He I lines marking this SN Type. This spectrum shows broad absorptions bluewards than 5000A, likely O II lines, which are similar to spectral features observed in super-luminous SNe at early epochs. The object has been spectroscopically monitored by PESSTO from 90 to 180 days after peak, and these spectra show the typical features observed in a number of SN 2006jc-like events, including a blue spectral energy distribution and prominent and narrow (v(FWHM) ~ 1900 km/s) He I emission lines. This suggests that the ejecta are interacting with He-rich circumstellar material. The detection of broad (10000 km/s) O I and Ca II features likely produced in the SN ejecta (including the [O I] 6300A,6364A doublet in the latest spectra) lends support to the interpretation of OGLE-2012-SN-006 as a core-collapse event.
description: 16 pages, 9 figures, 4 tables. Accepted by MNRAS
A Scoping Review of Hierarchical Medical System Policies in Mainland China Since the 2009 Health Reform
Creators: name: 蔡婷婷
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Medicine and Health Sciences
subject: Public Health

description: This study reviews China’s national policies related to hierarchical medical system (HMS) since China’s 2009 health system reform to characterize relevant policies
Breakdown of the Migdal-Eliashberg theory and a theory of lattice-fermionic superfluidity
Creators: name: Yuzbashyan, Emil A.
name: Altshuler, Boris L.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We show that the Migdal-Eliashberg theory loses validity at a finite value $λ_c$ of the electron-phonon coupling $λ$ regardless of the underlying model Hamiltonian. The value of $λ_c$ is approximately between 3.0 and 3.7. The new phase that emerges at $λ>λ_c$ breaks the lattice translational symmetry. Depending on the filling fraction and crystal symmetry, it is an insulator or a Fermi liquid. Its characteristic feature is a gap or a pronounced depression of the fermionic density of states near the Fermi level. We establish the breakdown from within the Migdal-Eliashberg theory by demonstrating that the normal state specific heat is negative for $λ\ge 3.7$ and the quasiparticle lifetime vanishes in the strong coupling limit. At fixed $λ>λ_c$, the transition to the new phase occurs at a critical temperature higher than the superconducting transition temperature. In addition, there is a first order phase transition between the new phase and the superconducting state as we vary $λ$ across $λ_c$ at fixed temperature. We put forward a new theory - lattice-fermionic theory of superfluidity - that bridges the gap between the Migdal-Eliashberg approach and the physics at stronger coupling. At small $λ$, our theory reduces to the Migdal-Eliashberg theory and, past $λ_c$, it describes the new phase and a range of other phenomena.
description: 24 pages, 5 figures, minor typos corrected & refs updated
A Spectro-Temporal Framework for Compensation of Reverberation for Speech Recognition
Creators: name: Kshitiz  Kumar
Publisher: name: Figshare
Year: 2018
Subjects: subject: Computer Engineering
subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The objective of this thesis is the development of signal processing and analysis techniques that would provide sharply improved speech recognition accuracy in highly reverberant environments. Speech is a natural medium of communication for humans, and in the last decade various speech technologies like automatic speech recognition (ASR), voice response systems etc. have considerably matured. The above systems rely on the clarity of the captured speech but many of the real-world environments include noise and reverberation that mitigate the system performance. The key focus of the thesis is on the robustness of ASR to reverberation.
In our work, we first provide a new framework to adequately and efficiently represent the problem of reverberation in speech feature domains. Although our framework incurs modeling approximation errors, we believe that it provides a good basis for developing reverberation compensation algorithms. Based on our framework, we successfully develop a number of dereverberation algorithms. The algorithms reduce the uncertainly involved in dereverberation tasks by using speech knowledge in terms of cepstral auto-correlation, cepstral distribution, and, non-negativity and sparsity of spectral values. We demonstrate the success of our algorithms on clean-training as well as matched-training.
Apart from dereverberation, we also provide an approach for noise robustness via a temporal-difference operation in the speech spectral domain. There, via a theoretical analysis, we predict an expected improvement in the SNR threshold shift for whitenoise conditions. We also empirically quantify and study speech-feature level distortion with respect to speech-signal level additive noise.
Finally, we provide a new framework for a joint reverberation and noise representation and compensation. The new framework generalizes the spectral domain reverberation framework by incorporating an additive noise term. Working under the new framework, we combine our dereverberation and noise compensation approaches for better dereverberation as well as for the most challenging speech recognition task that includes both noise and reverberation components.
A Note on the Analytic Structure of Celestial Amplitudes
Creators: name: Gu, Jiayin
name: Li, Ying-Ying
name: Wang, Lian-Tao
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Celestial amplitudes, obtained by applying Mellin transform and analytic continuation on "ordinary" amplitudes, have interesting properties which may provide useful insights on the underlying theory. Their analytic structures are thus of great interest and need to be better understood. In this paper, we critically examine the analytic structure of celestial amplitudes in a massless low-energy effective field theory. We find that, fixed-order loop contributions, which generate multipoles on the negative $β$-plane, in general do not provide an accurate description of the analytic structure of celestial amplitudes. By resumming over the leading logarithmic contributions using renormalization group equations (RGEs), we observe much richer analytic structures, which generally contain branch cuts. It is also possible to generate multipoles or shifted single poles if the RGEs satisfy certain relations. Including sub-leading logarithmic contributions is expected to introduce additional corrections to the picture. However, without a new approach, it is difficult to make a general statement since the analytic form of the Mellin transform is challenging to obtain.
description: 21 pages, 1 figure
Additional file 35 of Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales
Creators: name: Rassbach, Johannes
name: Hilsberg, Nathalie
name: Haensch, Veit G.
name: Dörner, Sebastian
name: Gressler, Julia
name: Sonnabend, Robin
name: Semm, Caroline
name: Voigt, Kerstin
name: Hertweck, Christian
name: Gressler, Markus
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Organic Chemistry
subject: FOS: Chemical sciences

description: Additional file 35: Figure S31. Activity of LinB during competitive substrate supply.
Anomalous Bootstrap on the half line
Creators: name: Berenstein, David
name: Hulsey, George
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study carefully the problem of the bootstrap on the half line. We show why one needs the full set of constraints derived from the Stieltjes theorem on the moment problem by reexamining previous results on the hydrogen atom. We also study the hydrogen atom at continuous angular momentum. We show that the constraints on the moment problem alone do not fix the boundary conditions in all cases and at least one of the positive matrices needs to be slightly enlarged to remove unphysical branches. We explain how to solve the more general problem of the bootstrap for Robin boundary conditions. The recursion relations that are usually used receive additional anomalous contributions. These corrections are necessary to compute the moments of the measure. We apply these to the linear potential and we show how the bootstrap matches the analytical results, based on the Airy function, for this example.
description: 31 pages, 11 figures. v2: We added an anomaly for n=0 that was omitted accidentally. Fixed a problem of conventions of factors of 2 between the text on the paper and the code we developed for the Airy function. v3: typos fixed
The serpentine representation of the infinite symmetric group and the basic representation of the affine Lie algebra $\widehat{\mathfrak{sl}_2}$
Creators: name: Tsilevich, N.
name: Vershik, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 20G05, 22E66

description: We introduce and study the so-called serpentine representations of the infinite symmetric group $\sinf$, which turn out to be closely related to the basic representation of the affine Lie algebra $\widehat{\mathfrak{sl}_2}$ and representations of the Virasoro algebra. This is a new version of the manuscript of the same authors "On a relation between the basic representation of the affine Lie algebra $\widehat\sl$ and a Schur--Weyl representation of the infinite symmetric group" (arXiv:1403.1558)
description: 18 pp., Ref.14. arXiv admin note: substantial text overlap with arXiv:1403.1558
Rudolf Redtenbacher, Sohn von Ferdinand Redtenbacher (1809-1863) an Ottilie Grossbach (1836-1919), verheiratete von Deschwanden, aufbewahrt im Nachlass von Joseph Wolfgang von Deschwanden (1819-1866)
Creators: name: Redtenbacher, Rudolf
Publisher: name: [s.n.]
Year: 1879

description: Brief aus Stuttgart
Dominicus Mazughs Tractatus in libros Metaphysicorum: Transkription aus dem Cod. StiBiEbg 524n3 (Kloster Engelberg)
Creators: name: Paladini, Chiara
Publisher: name: Zenodo
Year: 2023
Subjects: History of Philosophy
History of Metaphysics
History of Ontology
Swiss History
History of the Jesuits
Philosophy of the Early Modern Age
Second Scholasticism

description: Here I present the first version of the transcription of theTractatus in libros Metaphysicorum von Dominicus Mazugh aus dem Cod. StiBiEbg 524n3 (Kloster Engelberg), which collects Mazugh's lectures in metaphysics, held at the Engelberg Monastery in 1642. The transcription of the text was carried out at the Lucerne Faculty of Theology within the SNSF project "Zwischen monastischer und reformierter Metaphysik. Die schweizerische 'Wiege' der Ontologie im Zeitalter der Reformation" (SNSF project 100012_192559 - applicant: Prof. Dr. Giovanni Ventimiglia (TF- University of Lucerne), Employees: Marco Lamanna, Chiara Paladini. The project aimed to redefine the "cartography" of the Reformation in Switzerland on the traces of metaphysics teaching (Reportationes) in Swiss educational institutions and monastic poles, and thereby to gain a precise place for Swiss studies in the panorama of research on metaphysics and ontology in the early modern period. The project was based on a preliminary investigation that made it possible to recover new texts transmitting lessons on metaphysics held in Lucerne and Engelberg. The method was 1. to produce a systematic and comprehensive documentation based on an index of manuscripts and printed texts, most of them already identified, which testify to the existence of a cultural flourishing in Switzerland that has so far remained unexplored. 2. this documentation should be placed on a solid textual basis by transcribing and eventually critically editing those texts judged to be of interest in terms of their content and influence, in order to make them accessible to the scholarly community and to readers. 3. finally, we will examine the specific aspects of the teachings transmitted in these manuscripts.
description: The transcription was carried out as part of a project funded by the Swiss National Science Foundation (SNSF). Grant number: 192559
Hydrostatic pressure induced transition from δTc to δl pinning mechanism in MgB2
Creators: name: Shabbir, Babar
name: Wang, Xiaolin
name: Ghorbani, S. R.
name: Dou, Shixue
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The impact of hydrostatic pressure up to 1.2 GPa on the critical current density (Jc) and the nature of the pinning mechanism in MgB2 have been investigated within the framework of the collective theory. We found that the hydrostatic pressure can induce a transition from the regime where pinning is controlled by spatial variation in the critical transition temperature (δT_c) to the regime controlled by spatial variation in the mean free path (δl). Furthermore, Tc and low field Jc are slightly reduced, although the Jc drops more quickly at high fields than at ambient pressure. We found that the pressure raises the anisotropy and reduces the coherence length, resulting in weak interaction of the vortex cores with the pinning centres. Moreover, the hydrostatic pressure can reduce the density of states [Ns(E)], which, in turn, leads to a reduction in the critical temperature from 39.7 K at P = 0 GPa to 37.7 K at P = 1.2 GPa.
Visualizing and Understanding Large-Scale Bayesian Networks
Creators: name: Cossalter, Michele
name: Mengshoel, Ole J
name: Selker, Ted
Publisher: name: Figshare
Year: 2018
Subjects: subject: Computer Engineering
subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: Bayesian networks are a theoretically well-founded approach to represent large multi-variate probability distributions, and have proven useful in a broad range of
applications. While several software tools for visualizing
and editing Bayesian networks exist, they have important
weaknesses when it comes to enabling users to clearly understand and compare conditional probability tables in the context of network topology, especially in large-scale networks. This paper describes a system for improving the ability for computers to work with people to develop intelligent systems through the construction of high-performing Bayesian networks. We describe NetEx, a tool developed as a Cytoscape plugin, which allows a user to visually inspect and compare details concerning multiple nodes in a Bayesian network while maintaining awareness of their network context. It uses a “thought bubble line” to connect nodes in a graph representation and their internal information at the side of the graph. The tool seeks to improve the ability of experts to analyze and debug large Bayesian network models, and to help people to  understand how alternative algorithms and Bayesian networks operate, providing insights into how to improve them.
Computation of NMR shieldings at the CASSCF level using gauge-including atomic orbitals and Cholesky decomposition
Creators: name: Nottoli, Tommaso
name: Burger, Sophia
name: Stopkowicz, Stella
name: Gauss, Jürgen
name: Lipparini, Filippo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We present an implementation of coupled-perturbed complete active space self-consistent field (CP-CASSCF) theory for the computation of nuclear magnetic resonance chemical shifts using gauge-including atomic orbitals and Cholesky decomposed two-electron integrals. The CP-CASSCF equations are solved using a direct algorithm where the magnetic Hessian matrix-vector product is expressed in terms of one-index transformed quantities. Numerical tests on systems with up to about 1300 basis functions provide information regarding both the computational efficiency and limitations of our implementation.
Massive stars exploding in a He-rich circumstellar medium. IV. Transitional Type Ibn Supernovae
Creators: name: Pastorello, A.
name: Benetti, S.
name: Brown, P. J.
name: Tsvetkov, D. Y.
name: Inserra, C.
name: Taubenberger, S.
name: Tomasella, L.
name: Fraser, M.
name: Rich, D. J.
name: Botticella, M. T.
name: Bufano, F.
name: Cappellaro, E.
name: Ergon, M.
name: Gorbovskoy, E. S.
name: Harutyunyan, A.
name: Huang, F.
name: Kotak, R.
name: Lipunov, V. M.
name: Magill, L.
name: Miluzio, M.
name: Morrell, N.
name: Ochner, P.
name: Smartt, S. J.
name: Sollerman, J.
name: Spiro, S.
name: Stritzinger, M. D.
name: Turatto, M.
name: Valenti, S.
name: Wang, X.
name: Wright, D. E.
name: Yurkov, V. V.
name: Zampieri, L.
name: Zhang, T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present ultraviolet, optical and near-infrared data of the Type Ibn supernovae (SNe) 2010al and 2011hw. SN 2010al reaches an absolute magnitude at peak of M(R) = -18.86 +- 0.21. Its early light curve shows similarities with normal SNe Ib, with a rise to maximum slower than most SNe Ibn. The spectra are dominated by a blue continuum at early stages, with narrow P-Cygni He I lines indicating the presence of a slow-moving, He-rich circumstellar medium. At later epochs the spectra well match those of the prototypical SN Ibn 2006jc, although the broader lines suggest that a significant amount of He was still present in the stellar envelope at the time of the explosion. SN 2011hw is somewhat different. It was discovered after the first maximum, but the light curve shows a double-peak. The absolute magnitude at discovery is similar to that of the second peak (M(R) = -18.59 +- 0.25), and slightly fainter than the average of SNe Ibn. Though the spectra of SN 2011hw are similar to those of SN 2006jc, coronal lines and narrow Balmer lines are cleary detected. This indicates substantial interaction of the SN ejecta with He-rich, but not H-free, circumstellar material. The spectra of SN 2011hw suggest that it is a transitional SN Ibn/IIn event similar to SN 2005la. While for SN 2010al the spectro-photometric evolution favours a H-deprived Wolf-Rayet progenitor (of WN-type), we agree with the conclusion of Smith et al. (2012) that the precursor of SN 2011hw was likely in transition from a luminous blue variable to an early Wolf-Rayet (Ofpe/WN9) stage.
description: 23 pages, 11 figures, 6 tables. Accepted by MNRAS
Triple Regge exchange and transverse single-spin asymmetries of the very forward neutral pion production in polarized $p+p$ collisions
Creators: name: Kim, Hee-Jin
name: Clymton, Samson
name: Kim, Hyun-Chul
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Recently, the RHICf Collaboration measured the transverse single-spin asymmetries of the very forward neutral pion in polarized $p+p$ collisions at $\sqrt{s}=510$ GeV, produced at large pseudorapidity ($η\gtrsim 6$). The data show large asymmetries both in longitudinal momentum fraction $x_F$ and transverse momentum $p_T$ at $p_T<1\,\mathrm{GeV}/c$. Employing baryonic triple Regge exchanges, we describe the complete RHICf data for the first time and show that the neutral pion production at low $p_T$ can be interpreted as a diffractive one.
description: 5 pages, 4 figures
Additional file 36 of Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales
Creators: name: Rassbach, Johannes
name: Hilsberg, Nathalie
name: Haensch, Veit G.
name: Dörner, Sebastian
name: Gressler, Julia
name: Sonnabend, Robin
name: Semm, Caroline
name: Voigt, Kerstin
name: Hertweck, Christian
name: Gressler, Markus
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Organic Chemistry
subject: FOS: Chemical sciences

description: Additional file 36: Figure S32. Determination of the optimal reaction conditions for LinB.
Cholinergic REST-G9a gene repression through HMGB1-TLR4 neuroimmune signaling regulates basal forebrain cholinergic neuron phenotype
Creators: name: Crews, Fulton T.
name: Vetreno, Ryan P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Lipopolysaccharide (LPS) and high-mobility group box 1 (HMGB1) are Toll-like receptor (TLR4) agonists that activate proinflammatory neuroimmune signaling linked to loss of basal forebrain cholinergic neurons (BFCNs) and cognitive deficits. Loss of choline acetyltransferase immunoreactive (ChAT + IR) BFCNs is generally interpreted as cell death, but recent in vivo studies find anti-inflammatory interventions restore adolescent ethanol exposure-induced persistent loss of adult ChAT + IR neurons and cognitive deficits, suggesting proinflammatory signaling-induced reversible gene repression of ChAT in BFCNs. Using an ex vivo Wistar rat basal forebrain slice culture (FSC) model to investigate TLR4 involvement in repression of the BFCN phenotype, we report that direct TLR4 activation with LPS decreases expression of multiple BFCN markers in the absence of observable neuronal loss or cell death. Inhibition of HMGB1 blunts while inhibition of TLR4 blocks the LPS-induced loss of ChAT + IR neurons. TLR4 activation induces the transcriptional repressor RE1-silencing transcription factor (REST) and the methyltransferase G9a while increasing repressive histone 3 lysine 9 dimethylation and REST occupancy at cholinergic gene promoters. G9a inhibitors both prevent and reverse the LPS-induced loss of ChAT + IR whereas siRNA inhibition of REST blocks the LPS-induced loss of ChAT + IR BFCNs. These data suggest in vivo HMGB1-TLR4 signaling in BFCNs leads to a reversible loss of the cholinergic neuron phenotype through epigenetic gene repressive mechanisms.
Determination of hydrogen concentration in solids by transmission ERDA under nuclear-elastically enhanced recoiling of H by 8 and 9 MeV He
Creators: name: Kudo, Hiroshi
name: Kurosawa, Masanori
name: Naramoto, Hiroshi
name: Sataka, Masao
name: Ishii, Satoshi
name: Sasa, Kimikazu
name: Tomita, Shigeo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Hydrogen concentrations in thin self-supporting samples of polyphenylene sulfide and muscovite have been determined by nuclear-elastic recoil detection analysis of transmission layout. The analysis procedure is based only on the database of stopping power and recoil cross section for material analysis, without using any reference sample of known H content. For the polyphenylene sulfide sample, the determined value of $(2.87\pm 0.26)\times 10^{22}\,{\rm H}/$cm$^{3}$ is in good agreement with the calculated value of $3.01 \times 10^{22}\,{\rm H}/$cm$^{3}$. For the muscovite sample, the H concentration originating each from bound water and absorbed water is uniform over the entire thickness of the sample. The determined concentration $(9.43 \pm 0.75) \times 10^{21}$ H$/$cm$^{3}$ of the muscovite agrees excellently with the value of $9.36 \times 10^{21}$ H$/$cm$^{3}$ obtained from other quantitative analyses typically applied for minerals. The present results demonstrate the capability of accurate determination of H contents in materials and minerals by transmission ERDA.
description: 15 pages, 6 figures
Louise Kälin an Ottilie Grossbach (1836-1919), verheiratete von Deschwanden, aufbewahrt im Nachlass von Joseph Wolfgang von Deschwanden (1819-1866)
Creators: name: Kälin, Louise
Publisher: name: [s.n.]
Year: 1865

description: Brief aus Oberstrass (Zürich), übermittelt Grüsse "des Onkels"
Additional file 37 of Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales
Creators: name: Rassbach, Johannes
name: Hilsberg, Nathalie
name: Haensch, Veit G.
name: Dörner, Sebastian
name: Gressler, Julia
name: Sonnabend, Robin
name: Semm, Caroline
name: Voigt, Kerstin
name: Hertweck, Christian
name: Gressler, Markus
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Organic Chemistry
subject: FOS: Chemical sciences

description: Additional file 37: Figure S33. Clinker comparison between linA gene loci in Kickxellales.
L. Horner-Escher an Herr Horner, aufbewahrt im Nachlass von Joseph Wolfgang von Deschwanden (1819-1866)
Creators: name: Horner-Escher, L.
Publisher: name: [s.n.]
Year: 1852

description: Brief ohne Ortsangabe, gerichtet an "Mein l. Herr Horner", unterzeichnet mit: "Ihre freundschaftlich ergebene Tante", mit Präzisierungen zu einem Lohnbezug
Todesanzeige für Ottilie Grossbach (1836-1919), verheiratete von Deschwanden, aufbewahrt im Nachlass von Joseph Wolfgang von Deschwanden (1819-1866)
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1919

description: Gedruckte Todesanzeige für Ottilie von Deschwanden, geb. Grossbach, gestorben im Februar 1919, unterzeichnet u.a. von Ottilie und Alfred Gurdi