cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Simulations of Air-assisted Primary Atomization at Different Air-to-Liquid Injection Angles for Entrained Flow Gasification
Creators: name: Zhang, Feichi
name: Zirwes, Thorsten
name: Wachter, Simon
name: Jakobs, Tobias
name: Habisreuther, Peter
name: Zarzalis, Nikolaos
name: Trimis, Dimosthenis
name: Kolb, Thomas
name: Bockhorn, H.
Publisher: name: Karlsruher Institut für Technologie (KIT)
Year: 2021

description: Highly-resolved numerical simulations have been performed for a coaxial, twin-fluid nozzle, which is designed for fundamental research of the atomization process in entrained flow gasification (EFG). Objective of the work is to reveal specifically the influence of the relative injection angle $\alpha$ between the central liquid jet and the annular airflow (external-mixing) on the primary atomization. A glycerol/water mixture with a dynamic viscosity of 200 mPa·s is atomized at atmospheric condition and with a gas-toliquid ratio of 0.6. The angle of attack between liquid and airflow has been varied from $\alpha$ = 0° to 60°. The computational grid consists of approx. 10 million cells, using a smallest resolution of 25 µm. In agreement with the corresponding experiment, the calculated breakup morphology is characterized by a pulsating mode destabilization, accompanied by disintegration of membrane-type ligaments. The breakup of the liquid jet is found to be enhanced from $\alpha$ = 0° to 30°, which leads to a decrease of the liquid core length $L_C$. This is attributable to a reinforced aerodynamic interaction or an enhanced multiphase momentum transfer from the gas to the liquid phase, respectively. The gas flow velocity close to the liquid jet is increased in this case, which is in accordance with results obtained from the PIV measurement. The reason for the increase of local flow velocity is shown to be caused by an increased local static pressure at the base of the liquid jet with increased $\alpha$, which results in a favorable pressure gradient in main flow direction. However, further increase of $\alpha$ from 30° to 60° leads to a decreased flow velocity around the liquid jet, so that $L_C$ increases and the atomization performance decreases with $\alpha$. The behavior is further elucidated by means of the multiphase momentum exchange or the liquid phase kinetic energy, which increase from $\alpha$ = 0° to 30° and decreases with further increased $\alpha$. The result reveals the essential impact of the nozzle design parameters on the atomization process in addition to the general operating parameters. In summary, there exists an optimal relative injection angle between the liquid and air streams in the range of 30°
Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo
Creators: name: Cabrita, Ines
name: Kraus, Andre
name: Scholz, Julia Katharina
name: Skoczynski, Kathrin
name: Schreiber, Rainer
name: Kunzelmann, Karl
name: Buchholz, Björn
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: 570 Biowissenschaften, Biologie

description: In autosomal dominant polycystic kidney disease (ADPKD) multiple bilateral renal cysts gradually enlarge, leading to a decline in renal function. Transepithelial chloride secretion through cystic fibrosis transmembrane conductance regulator (CFTR) and TMEM16A (anoctamin 1) are known to drive cyst enlargement. Here we demonstrate that loss of Pkd1 increased expression of TMEM16A and CFTR and Cl− secretion in murine kidneys, with TMEM16A essentially contributing to cyst growth. Upregulated TMEM16A enhanced intracellular Ca2+ signaling and proliferation of Pkd1-deficient renal epithelial cells. In contrast, increase in Ca2+ signaling, cell proliferation and CFTR expression was not observed in Pkd1/Tmem16a double knockout mice. Knockout of Tmem16a or inhibition of TMEM16A in vivo by the FDA-approved drugs niclosamide and benzbromarone, as well as the TMEM16A-specific inhibitor Ani9 largely reduced cyst enlargement and abnormal cyst cell proliferation. The present data establish a therapeutic concept for the treatment of ADPKD.
Code Drift: Towards Idempotent Neural Audio Codecs
Creators: name: O'Reilly, Patrick
name: Seetharaman, Prem
name: Su, Jiaqi
name: Jin, Zeyu
name: Pardo, Bryan
Publisher: name: arXiv
Year: 2024
Subjects: subject: Audio and Speech Processing (eess.AS)
subject: Sound (cs.SD)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Neural codecs have demonstrated strong performance in high-fidelity compression of audio signals at low bitrates. The token-based representations produced by these codecs have proven particularly useful for generative modeling. While much research has focused on improvements in compression ratio and perceptual transparency, recent works have largely overlooked another desirable codec property -- idempotence, the stability of compressed outputs under multiple rounds of encoding. We find that state-of-the-art neural codecs exhibit varied degrees of idempotence, with some degrading audio outputs significantly after as few as three encodings. We investigate possible causes of low idempotence and devise a method for improving idempotence through fine-tuning a codec model. We then examine the effect of idempotence on a simple conditional generative modeling task, and find that increased idempotence can be achieved without negatively impacting downstream modeling performance -- potentially extending the usefulness of neural codecs for practical file compression and iterative generative modeling workflows.
description: ICASSP 2025
10X Multiome GEX + ATAC human spinal cord cell ranger arc processed data (sample processed as 1)
Creators: name: , Zhang
Publisher: name: Zenodo
Year: 2023
Subjects: 10X multiome (Gene expression + ATAC)

description: Sample 2,3, and 4 processed together by cell ranger arc as one. FASTQ not uploaded because of the size. File here contains: 1. filtered_feature_bc_matrix 2. atac_fragments.tsv.gz.tbi 3. atac_fragmnets.tsv.gz 4. meta-data file detailing sample number for each cell These were used for downstream processing such as clustering etc.
Champions of cultural safety : an exploration of how cultural safety can be implemented as a routine aspect of health care.
Creators: name: Foster, Paula
Publisher: name: University of British Columbia
Year: 2017

description: Background: This study explores the perspectives of Champions of Cultural Safety and will potentially contribute to an Aboriginal Health team’s knowledge development of a current pilot project on Indigenous Cultural Competency transformation. This study identified healthcare providers (HCPs) who are Champions of Cultural Safety and explored their experiences practicing culturally safe care in their hospital. This study is timely given the current commitment to cultural safety and cultural humility in health services within the BC Tripartite Framework Agreement. Conducted with the guidance of the health authority’s Aboriginal Health Team, this inquiry may also assist HCPs in taking a cultural safety approach when providing healthcare in the face of ongoing racism and discrimination towards Indigenous people in healthcare and society. Methods: Using an exploratory, ethnographic, qualitative research design, recruitment began with Aboriginal Patient Navigators (APNs) who identified health care providers representing Champions of Cultural Safety. Snowball sampling was used until 8 participants from a variety of health care disciplines were recruited. Semi structured, in depth interviews were conducted with the APNs, an Elder and HCPs. Post-colonial theoretical perspectives informed the analysis and overall inquiry. A thematic analysis was conducted using constant comparison methods. Findings: The key findings are: 1) The client and health care provider relationship is the cornerstone of cultural safety (CS), 2) The organizational strategies to support CS are insufficient in the current, pervasive and conventional biomedical, organizational context, 3) Structural barriers to CS persist in the colonial context. These findings demonstrate the complexities and intersections of the HCP/client relationship, the organizational strategies to support CS and the current systemic barriers constraining the participants’ abilities to provide CS care. Discussion: The findings prompt three discussion areas: 1) The client and health care provider relationship is the cornerstone of CS, for both the client and health care provider when analyzed from a CS lens, 2) Many key characteristics of the hospital and wider health care context conflicts with a CS approach to care, 3) Structural violence characterized by racism and discrimination exists within the hospital environment, demonstrating a need for organizational interventions to address the continued Indigenous health inequities.
An algebraic classification of entangled states
Creators: name: Buniy, Roman V.
name: Kephart, Thomas W.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We provide a classification of entangled states that uses new discrete entanglement invariants. The invariants are defined by algebraic properties of linear maps associated with the states. We prove a theorem on a correspondence between the invariants and sets of equivalent classes of entangled states. The new method works for an arbitrary finite number of finite-dimensional state subspaces. As an application of the method, we considered a large selection of cases of three subspaces of various dimensions. We also obtain an entanglement classification of four qubits, where we find 27 fundamental sets of classes.
description: published version
RNA and DNA Binding Epitopes of the Cold Shock Protein TmCsp from the Hyperthermophile Thermotoga maritima
Creators: name: König, Konstanze von
name: Kachel, Norman
name: Kalbitzer, Hans Robert
name: Kremer, Werner
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: Cold-shock protein · TmCsp · Thermotoga maritima · Single-stranded DNA · Single-stranded RNA · Protein/ ssDNA complex · Protein/RNA complex · NMR spectroscopy · Temperature sensing
subject: 570 Biowissenschaften, Biologie

description: Prokaryotic cold shock proteins (CSPs) are considered to play an important role in the transcriptional and translational regulation of gene expression, possibly by acting as transcription anti-terminators and “RNA chaperones”. They bind with high affinity to single-stranded nucleic acids. Here we report the binding epitope of TmCsp from Thermotoga maritima for both single-stranded DNA and RNA, using heteronuclear 2D NMR spectroscopy. At “physiological” growth temperatures of TmCsp (≥ 343 K), all oligonucleotides studied have dissociation constants between 1.6 ((dT)7) and 25.2 ((dA)7) μM as determined by tryptophan fluorescence quenching. Reduction of the temperature to 303 K leads to a pronounced increase of affinity for thymidylate (dT)7 and uridylate (rU)7 heptamers with dissociation constants of 4.0 and 10.8 nM, respectively, whereas the weak binding of TmCsp to cytidylate, adenylate, and guanylate heptamers (dC)7, (dA)7, and (dT)7 is almost unaffected by temperature. The change of affinities of TmCsp for (dT)7 and (rU)7 by approximately 3 orders of magnitude shows that it represents a cold chock sensor that switches on the cold shock reaction of the cell. A temperature dependent conformational switch of the protein is required for this action. The binding epitope on TmCsp for the ssDNA and RNA heptamers is very similar and comprises β-strands 1 and 2, the loop β1–β2 as well as the loops connecting β3 with β4 and β4 with β5. Besides the loop regions, surprisingly, mainly the RNA-binding motif RNP1 is involved in ssDNA and RNA binding, while only two amino acids, H28 and W29, of the postulated RNA-binding motif RNP2 interact with the uridylate and thymidylate homonucleotides, although a high affinity in the nanomolar range is achieved. This is in contrast to the binding properties of other CSPs or cold shock domains, where RNP1 as well as RNP2 are involved in binding. TmCsp takes up a unique position since it is the only one which possesses a tryptophan residue instead of a usually highly conserved phenylalanine or tyrosine residue at the end of RNP2. NMR titrations suggest that neither (dT)7 nor (rU)7 represent the full binding motif and that non-optimal intercalation of W29 into these oligonucleotides blocks the access of the RNP2 site to the DNA or RNA. NMR-experiments with (dA)7 suggest an interaction of W29 with the adenine ring. Full binding seems to require at least one single purine base well-positioned within a thymine- or uracil-rich stretch of nucleic acids.
Representación política femenina descriptiva en el Congreso Nacional brasileño (legislatura 2023-2027) y la crítica a la categoría de interseccionalidad
Creators: name: Fernandes Gonçalves, Juliana Alice
Publisher: name: Zenodo
Year: 2023
Subjects: Congreso Nacional brasileño
Interseccionalidad
Mujeres en la política
Neoinstitucionalismo feminista
Representación política de las mujeres

description: Juliana Alice Fernandes Gonçalves. 2023. Representación política femenina descriptiva en el Congreso Nacional brasileño (legislatura 2023-2027) y la crítica a la categoría de interseccionalidad. Documento de Trabajo No. 29. México: Observatorio de Reformas Políticas en América Latina, IIJ-UNAM y Organización de los Estados Americanos (OEA).
Thermal leptogenesis in a TeV scale model for neutrino masses
Creators: name: Suematsu, Daijiro
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It is known that the radiative neutrino mass model proposed by Ma could be a consistent framework for dark matter, leptogenesis and suppressed lepton flavor violation if a neutral component of the inert doublet is identified as dark matter and the right-handed neutrinos are of O(10^7) GeV or more. In the same model we explore another scenario such that right-handed neutrinos are in TeV regions and their lightest one is dark matter. It is shown that this scenario requires fine mass degeneracy to generate the appropriate baryon number asymmetry as in the case of resonant leptogenesis. As long as we impose the model to induce the baryon number asymmetry on the basis of thermal leptogenesis, we find that dark matter abundance can not be explained. If this scenario is adopted, the model has to be extended to include some new mechanism to explain it.
description: 21 pages, 3 figures, v2:large improvement by the analysis of Boltzmann equations, title changed, v3: abstract rewritten, some references added, accepted version for publication
Black Hole Mass Estimates Based on CIV are Consistent with Those Based on the Balmer Lines
Creators: name: Assef, R. J.
name: Denney, K. D.
name: Kochanek, C. S.
name: Peterson, B. M.
name: Kozlowski, S.
name: Ageorges, N.
name: Barrows, R. S.
name: Buschkamp, P.
name: Dietrich, M.
name: Falco, E.
name: Feiz, C.
name: Gemperlein, H.
name: Germeroth, A.
name: Grier, C. J.
name: Hofmann, R.
name: Juette, M.
name: Khan, R.
name: Kilic, M.
name: Knierim, V.
name: Laun, W.
name: Lederer, R.
name: Lehmitz, M.
name: Lenzen, R.
name: Mall, U.
name: Madsen, K. K.
name: Mandel, H.
name: Martini, P.
name: Mathur, S.
name: Mogren, K.
name: Mueller, P.
name: Naranjo, V.
name: Pasquali, A.
name: Polsterer, K.
name: Pogge, R. W.
name: Quirrenbach, A.
name: Seifert, W.
name: Stern, D.
name: Shappee, B.
name: Storz, C.
name: Van Saders, J.
name: Weiser, P.
name: Zhang, D.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Using a sample of high-redshift lensed quasars from the CASTLES project with observed-frame ultraviolet or optical and near-infrared spectra, we have searched for possible biases between supermassive black hole (BH) mass estimates based on the CIV, Halpha and Hbeta broad emission lines. Our sample is based upon that of Greene, Peng & Ludwig, expanded with new near-IR spectroscopic observations, consistently analyzed high S/N optical spectra, and consistent continuum luminosity estimates at 5100A. We find that BH mass estimates based on the FWHM of CIV show a systematic offset with respect to those obtained from the line dispersion, sigma_l, of the same emission line, but not with those obtained from the FWHM of Halpha and Hbeta. The magnitude of the offset depends on the treatment of the HeII and FeII emission blended with CIV, but there is little scatter for any fixed measurement prescription. While we otherwise find no systematic offsets between CIV and Balmer line mass estimates, we do find that the residuals between them are strongly correlated with the ratio of the UV and optical continuum luminosities. Removing this dependency reduces the scatter between the UV- and optical-based BH mass estimates by a factor of approximately 2, from roughly 0.35 to 0.18 dex. The dispersion is smallest when comparing the CIV sigma_l mass estimate, after removing the offset from the FWHM estimates, and either Balmer line mass estimate. The correlation with the continuum slope is likely due to a combination of reddening, host contamination and object-dependent SED shapes. When we add additional heterogeneous measurements from the literature, the results are unchanged.
description: Accepted for publication in The Astrophysical Journal. 37 text pages + 8 tables + 23 figures. Updated with comments by the referee and with a expanded discussion on literature data including new observations
Detecting unresolved moving sources in a diffuse background
Creators: name: Geringer-Sameth, Alex
name: Koushiappas, Savvas M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present a statistical technique which can be used to detect the presence and properties of moving sources contributing to a diffuse background. The method is a generalization of the 2-point correlation function to include temporal as well as spatial information. We develop a formalism which allows for a derivation of the spacetime 2-point function in terms of the properties of the contributing sources. We test this technique in simulated sky maps, and demonstrate its robustness in identifying the presence of moving and stationary sources. Applications of this formalism to the diffuse gamma-ray background include searches for solar system bodies, fast moving primordial black holes, and dense cores of dark matter proto-halos in the solar neighborhood. Other applications include detecting the contribution of energetic neutrinos originating in the solar system, as well as probing compact objects in long timeline lensing experiments.
description: 18 pages, 7 figures
Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
Creators: name: Unkn
Publisher: name: unkn
Year: 2021

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 49, 1893
Quandle cocycle invariants of links using Mochizuki's 3-cocycles and Dijkgraaf-Witten invariants of 3-manifolds
Creators: name: Nosaka, Takefumi
Publisher: name: arXiv
Year: 2011
Subjects: subject: Geometric Topology (math.GT)
subject: Algebraic Geometry (math.AG)
subject: Algebraic Topology (math.AT)
subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: T. Mochizuki determined all 3-cocycles of the third quandle cohomologies of Alexander quandles on finite fields. We show that all the 3-cocycles, except those of 2-cocycle forms, are derived from group 3-cocycles of a meta-abelian group. Further, the quandle cocycle invariant of a link using Mochizuki's 3-cocycle is equivalent to a $\Z$-equivariant part of the Dijkgraaf-Witten invariant of a cyclic covering of $S^3$ branched over the link using the group. We compute some Massey triple products via the former invariant.
description: The results in this paper will be generalized in another paper
Activity Patterns and Age-dependent Changes in Behavior in the Clonal Ant Platythyrea punctata
Creators: name: Hartmann, Clara
name: Haschlar, Julia
name: Heinze, Jürgen
name: Bernadou, Abel
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: Division of labor . Colony activity . Age polyethism. Lifespan . Platythyrea punctata
subject: 570 Biowissenschaften, Biologie

description: Age-based polyethism, wherein young individuals perform tasks within the nest and later transition to outside activities, is common among many social insects. This division of labor ensures the safety of workers with longer residual lifespans, such as brood caring nurses, and exposes only old individuals to increased extrinsic mortality risks. It appears however, that lifespan in workers is also shaped by intrinsic factors, such as senescence. The transition from nurse to forager is accompanied by various physiological and behavioral changes and seems to represent a crucial step in determining the subsequent life history of the individual. Here we investigate the daily activity pattern and detailed division of labor in colonies of the clonal ant Platythyrea punctata to better understand the dynamics of age polyethism in this peculiar species. We found that P. punctata colonies were mostly active during the day. At night, few workers were observed out of their nests. Workers showed a decrease in brood care and aggressive behavior over time. With increasing age individuals spent more time outside the nest and were more frequently observed walking. However, the transition to outside tasks did not follow a consistent time pattern in all colonies. Workers transitioning at a younger age seemed to die earlier than workers that began to forage later in life.
Manin's conjecture for two quartic del Pezzo surfaces with 3A_1 and A_1+A_2 singularity types
Creators: name: Boudec, Pierre Le
Publisher: name: arXiv
Year: 2010
Subjects: subject: Number Theory (math.NT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 11D45, 14G05

description: We prove Manin's conjecture for two del Pezzo surfaces of degree four which are split over Q and whose singularity types are respectively 3A_1 and A_1+A_2. For this, we study a certain restricted divisor function and use a result about the equidistribution of its values in arithmetic progressions. In this task, Weil's bound for Kloosterman sums plays a key role.
description: Final version
Seedlings of alpine species do not have better frost-tolerance than their lowland counterparts
Creators: name: Rosbakh, Sergey
name: Margreiter, Vera
name: Jelcic, Bernardica
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: Alps · Freezing · Frost tolerance · Lowland · Seedling
subject: 580 Pflanzen (Botanik)

description: In contrast to adult plants, little is known about the frost-tolerance of seedlings of alpine species, despite the fact that frost has been considered as one of the main factors limiting plant recruitment in high elevation. Here we report the results of a comparative study on seedling frost-tolerance of nine congeneric species pairs with lowland (0–900 m a.s.l.) and alpine (1800–2700 m a.s.l.) distribution. Similarly to adult alpine plants, we expected seedlings of alpine species to be more frost-tolerant than their lowland counterparts. Frost-tolerance was estimated under laboratory conditions by exposing seedlings to frost events from − 1 to − 9 °C, calculated as the temperature at which 50% of the seedlings were lethally damaged by frost (LT50). The LT50 values varied between − 1.95 and − 6.11 °C suggesting that seedling of all tested species could potentially survive mild and/or short frosts, but might be lethally damaged by severe and/or continuous frost events. The LT50 values for lowland and alpine species did not differ statistically and were on average − 3.96 ± 0.18 °C and − 4.16 ± 0.43 °C, respectively. These findings did not confirm our hypothesis that seedlings of alpine species have higher frost-tolerance than seedlings of lowland species. Four possible reasons could explain this pattern. They include (1) comparable levels of negative-stress in both lowland and alpine habitats, (2) opportunistic seed germination strategy in alpine plants, (3) peculiarities of our experimental set up and (4) potentially stronger effects of drought on alpine seedling survival than frost.
Coulomb gas ensembles and Laplacian growth
Creators: name: Hedenmalm, Haakan
name: Makarov, Nikolai
Publisher: name: arXiv
Year: 2011
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We consider the normal matrix ensemble under a general confining potential. We find that the eigenvalues condensate on a compact set in the plane, which we call the spectral droplet. We also study the evolution of incrementally adding a dimension, i.e., adding an extra electron in this fermionic model.
description: 43 pages
Book Review- The Philosophy of Bhagavadgita – Author: P. V. Laxmiprasad
Creators: name: Dr. Candy D Cunha
Publisher: name: Zenodo
Year: 2023

description: This book under review on The Philosophy of Bhagavadgita is written by a renowned critic and scholar P. V. Laxmiprasad, from Karimnagar, Telangana. It was published by Books Clinic, Bilaspur in 2021. It carries a well-written preface, a quote and dedication to three Indian Philosophers. The contents include four sections of the book 1) Indian Philosophy 2) Philosophy of Bhagavadgita 3) Conclusion 4) Works Cited.
The Management of Brain Metastases—Systematic Review of Neurosurgical Aspects
Creators: name: Schebesch, Karl-Michael
name: Doenitz, Christian
name: Höhne, Julius
name: Schmidt, Nils Ole
name: Proescholdt, Martin A.
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: brainmetastases; surgical resection; infiltration; neuronavigation; fluorescence-guided surgery
subject: 610 Medizin

description: The multidisciplinary management of patients with brain metastases (BM) consists of surgical resection, different radiation treatment modalities, cytotoxic chemotherapy, and targeted molecular treatment. This review presents the current state of neurosurgical technology applied to achieve maximal resection with minimal morbidity as a treatment paradigm in patients with BM. In addition, we discuss the contribution of neurosurgical resection on functional outcome, advanced systemic treatment strategies, and enhanced understanding of the tumor biology.
Bericht über die siebenundzwanzigste Generalversammlung vom 24. Juni 1892 in Sigmaringen
Creators: name: ,
Publisher: name: unkn
Year: 2021

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 49, 1893
Bridging Knowledge Gaps in Security Analytics
Creators: name: Böhm, Fabian
name: Vielberth, Manfred
name: Pernul, Günther
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: Security Analytics, Domain Knowledge, Visual Analytics, Security Awareness
subject: 004 Informatik

description: In a cyber-physical world, the number of links between corporate assets is growing and infrastructures are becoming more complex. This and related developments significantly enlarge the attack surface of organizations. Additionally, more and more attacks do not exploit technical vulnerabilities directly but gain a foothold through phishing or social engineering. Since traditional security systems prove to be no longer sufficient to detect incidents effectively, humans and their specialized knowledge are becoming a critical security factor. Therefore, it is vital to maintain an overview of the cybersecurity knowledge spread across the entire company. However, there is no uniform understanding of knowledge in the field of security analytics. We aim to close this gap by formalizing knowledge and defining a conceptual knowledge model in the context of security analytics. This allows existing research to be better classified and shows that individual areas offer much potential for future r esearch. In particular, the collaboration between domain experts but also between machines and employees could enable the exploitation of previously unused but crucial knowledge. For example, this knowledge is of great value for defining security rules in current security analytics systems. We introduce a proof of concept implementation using visual programming to showcase how even security novices can easily contribute their knowledge to security analytics.
Zum Andenken an Prof. Dr. Ernst Hofmann, Kustos am K. Naturalien-Kabinet zu Stuttgart
Creators: name: Steudel, Wilhelm
Publisher: name: unkn
Year: 2021

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 49, 1893
Self-energy effects in the Polchinski and Wick-ordered renormalization-group approaches
Creators: name: Katanin, A. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: I discuss functional renormalization group (fRG) schemes, which allow for non-perturbative treatment of the self-energy effects and do not rely on the one-particle irreducible functional. In particular, I consider Polchinski or Wick-ordered schemes with amputation of full (instead of bare) Green functions, as well as more general schemes, and eastablish their relation to the `dynamical adjustment propagator' scheme by M. Salmhofer [Ann. der Phys. 16, 171 (2007)]. While in the Polchinski scheme the amputation of full (instead of bare) Green functions improves treatment of the self-energy effects, the structure of the corresponding equations is not suitable to treat strong-coupling problems; it is not also evident, how the mean-field (MF) solution of these problems is recovered in this scheme. For Wick ordered scheme, excluding fully or partly tadpole diagrams one can obtain forms of fRG hierarchy, which are suitable to treat strong-coupling problems. In particular, I emphasize usefullness of the schemes, which are local in cutoff parameter, and compare them to the one-particle irreducible approach.
description: 13 pages; updated and extended version
Plasticity of behaviours modulated by alcohol
Creators: name: Lin, Conny Hsin-Cheng
Publisher: name: University of British Columbia
Year: 2018

description: In this dissertation, I investigated the ways that alcohol modulates plasticity of behaviours through studying effects of alcohol on body posture, locomotion, and a simple form of behavioral plasticity, habituation, in the genetic model organism Caenorhabditis elegans. I found that the effects of alcohol on body posture and locomotion are temporally dynamic especially for the first 30 min. Some earlier studies found alcohol facilitated habituation but others found alcohol inhibited habitation. I found that alcohol can both facilitate or inhibit habituation of the reversal response to repeated stimuli (taps) depending on the component of the reversal response assessed. Furthermore, I discovered that alcohol altered the predominant response to tap from a backward reversal to a forward acceleration. With this understanding, I examined the role of 27 genes on the alcohol induced behavioural changes characterized in Chapter 2. I found different alcohol modulated behaviors involved different sets of genes. For example, I observed that 2 genes modulated only body posture, 3 genes modulated only reversals, 1 gene modulated posture and acceleration but not reversal. I also discovered a gene not previously implicated in alcohol’s effect on behaviour: tomosyn, a negative regulator of SNARE complex. In the final study I investigated another alcohol modulated behavioural plasticity: tolerance. In C. elegans acute tolerance has been studied, however, chronic tolerance has not. I developed a chronic alcohol exposure paradigm and tested several candidate genes to determine whether they play a role in chronic tolerance to alcohol. I found that worms with a mutation in the Neuropeptide Y receptor, a gene that is involved in acute tolerance, had better chronic tolerance than wild-type worms. I then showed that mutations in genes that encode histone methyltransferases impaired chronic tolerance, which provided the first evidence relating histone methyltransferases with functional outcomes of alcohol exposure in adult animals. Together, the results from my dissertation contribute to our understanding of how alcohol alters behaviour.
Neue Beobachtungen über die Natur der vulkanischen Tuffgänge in der schwäbischen Alb und ihrem nördlichen Vorlande
Creators: name: Branca, Wilhelm
Publisher: name: unkn
Year: 2021

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 49, 1893
Effect of nuclear interactions of neutral kaons on CP asymmetry measurements
Creators: name: Ko, B. R.
name: Won, E.
name: Golob, B.
name: Pakhlov, P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We examine the effect of the difference in nuclear interactions of ${K}^0$ and $\bar{K}^0$ mesons on the measurement of CP asymmetry for experiments at $e^+e^-$ colliders - charm and $B$-meson factories. We find that this effect on CP asymmetry can be as large as 0.3%, and therefore sufficiently significant in interpreting measurements of CP asymmetry when neutral kaons are present in the final state.
description: accepted to PRD
Quantum computation with ultracold atoms in a driven optical lattice
Creators: name: Schneider, Philipp-Immanuel
name: Saenz, Alejandro
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We propose a scheme for quantum computation in optical lattices. The qubits are encoded in the spacial wavefunction of the atoms such that spin decoherence does not influence the computation. Quantum operations are steered by shaking the lattice while qubit addressability can be provided with experimentally available techniques of changing the lattice with single-site resolution. Numerical calculations show possible fidelities above 99% with gate times on the order of milliseconds.
description: 4 pages, 5 figures
Das angebliche Wrack der Arche Noae nach des Berosus und anderer Mitteilungen
Creators: name: Branca, Wilhelm
Publisher: name: unkn
Year: 2021

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 49, 1893
How Sequentially Changing Reward Prospect Modulates Meta-control: Increasing Reward Prospect Promotes Cognitive Flexibility
Creators: name: Fröber, Kerstin
name: Dreisbach, Gesine
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: Meta-control . Reward . Flexibility . Stability . Task switching
subject: 150 Psychologie

description: Meta-control is necessary to regulate the balance between cognitive stability and flexibility. Evidence from (voluntary) task switching studies suggests performance-contingent reward as one modulating factor. Depending on the immediate reward history, reward prospect seems to promote either cognitive stability or flexibility: Increasing reward prospect reduced switch costs and increased the voluntary switch rate, suggesting increased cognitive flexibility. In contrast, remaining high reward prospect increased switch costs and reduced the voluntary switch rate, suggesting increased cognitive stability. Recently we suggested that increasing reward prospect serves as a meta-control signal toward cognitive flexibility by lowering the updating threshold in working memory. However, in task switching paradigms with two tasks only, this could alternatively be explained by facilitated switching to the other of two tasks. To address this issue, a series of task switching experiments with uncued task switching between three univalent tasks was conducted. Results showed a reduction in reaction time (RT) switch costs to a nonsignificant difference and a high voluntary switch rate when reward prospect increased, whereas repetition RTs were faster, switch RTs slower, and voluntary switch rate was reduced when reward prospect remained high. That is, increasing reward prospect put participants in a state of equal readiness to respond to any target stimulus—be it a task repetition or a switch to one of the other two tasks. The study thus provides further evidence for the assumption that increasing reward prospect serves as a meta-control signal to increase cognitive flexibility, presumably by lowering the updating threshold in working memory.
Valley degeneracy in biaxially strained aluminum arsenide quantum wells
Creators: name: Prabhu-Gaunkar, S.
name: Birner, S.
name: Dasgupta, S.
name: Knaak, C.
name: Grayson, M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: This paper details a complete formalism for calculating electron subband energy and degeneracy in strained multi-valley quantum wells grown along any orientation with explicit results for the AlAs quantum well case. A standardized rotation matrix is defined to transform from the conventional- cubic-cell basis to the quantum-well-transport basis whereby effective mass tensors, valley vectors, strain matrices, anisotropic strain ratios, and scattering vectors are all defined in their respective bases. The specific cases of (001)-, (110)-, and (111)-oriented aluminum arsenide (AlAs) quantum wells are examined, as is the unconventional (411) facet, which is of particular importance in AlAs literature. Calculations of electron confinement and strain in the (001), (110), and (411) facets determine the critical well width for crossover from double- to single-valley degeneracy in each system. The notation is generalized to include miscut angles, and can be adapted to other multi-valley systems. To help classify anisotropic inter-valley scattering events, a new primitive unit cell is defined in momentum space which allows one to distinguish purely in-plane inter-valley scattering events from those that requires an out-of-plane momentum scattering component.
description: 17 pages, 4 figures, 2 tables
Splitting of roton minimum in the ν=5/2 Moore-Read state
Creators: name: Wright, Anthony R.
name: Rosenow, Bernd
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We calculate the dynamical structure factor of the ν=5/2 non-abelian quantum Hall state in the dipole approximation, valid for large momenta. Due to the fact that both quasi-particles (qps) and quasi-holes (qhs) have an internal Majorana degree of freedom, a qp-qh pair has a fermionic degree of freedom which can be either empty or occupied, and leads to a splitting of the roton mode. Observation of this splitting by means of finite wavelength optical spectroscopy could provide evidence for Majorana modes in the ν=5/2 quantum Hall state.
description: 8 pages including Supp. Mat., 3 figures
Ueber die Ursachen der Blitzschläge in Bäume
Creators: name: Jonesco, Dimitrie
Publisher: name: unkn
Year: 2021

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 49, 1893
A 2D Cd-based metal organic framework: synthesis, structure, selectively and sensitive sensing of Fe3+
Creators: name: Huang, Gui-Mei
name: Qin, Deng-Pan
name: Li, Chun-Huan
name: Cui, Lian-Sheng
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: A Cd-based metal organic framework (Cd-MOF), {Cd2[H(t-4-cpp)]2(bibp)2}n, was constructed using 2,4,6-tri(4-carboxylphenyl)pyridine [H3(t-4-cpp)] and 4,4'-bis(imidazolyl)biphenyl (bibp) through the solvothermal method. Its structure was characterized by X-ray single-crystal diffraction. Cd-MOF crystallizes in the triclinic system, P-1 space group and features a two-dimensional (2D) framework. The fluorescence quenching results showed that Cd-MOF can selectively and sensitively sense Fe3+ with a detection limit of 0.993 μM.
Exploring strange nucleon form factors on the lattice
Creators: name: Babich, Ronald
name: Brower, Richard C.
name: Clark, Michael A.
name: Fleming, George T.
name: Osborn, James C.
name: Rebbi, Claudio
name: Schaich, David
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We discuss techniques for evaluating sea quark contributions to hadronic form factors on the lattice and apply these to an exploratory calculation of the strange electromagnetic, axial, and scalar form factors of the nucleon. We employ the Wilson gauge and fermion actions on an anisotropic 24^3 x 64 lattice, probing a range of momentum transfer with Q^2 < 1 GeV^2. The strange electric and magnetic form factors, G_E^s(Q^2) and G_M^s(Q^2), are found to be small and consistent with zero within the statistics of our calculation. The lattice data favor a small negative value for the strange axial form factor G_A^s(Q^2) and exhibit a strong signal for the bare strange scalar matrix element _0. We discuss the unique systematic uncertainties affecting the latter quantity relative to the continuum, as well as prospects for improving future determinations with Wilson-like fermions.
description: 19 pages, 11 figures; v2 includes additional references; v3 as appears in PRD
Stress macht Zellen resistent gegen Folsäure-basierte Chemotherapeutika
Creators: name: Ahrends, Robert
name: Medenbach, Jan
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: 570 Biowissenschaften, Biologie

description: The unfolded protein response (UPR), a cellular stress response pathway, is broadly implicated in disease and resistance to therapy. The molecular mechanisms that drive stress-mediated chemoresistance are, however, only poorly understood. We have employed a multiomics approach to determine UPR-induced gene regulation, revealing the UPR regulon. We further observe metabolic rewiring upon stress and resistance to Methotrexate, a widely-employed therapeutic reagent. The precise molecular characterization of the pathway driving resistance might lead to novel concepts in cancer therapy.
Zur Charakteristik der häufigeren deutschen Raubvögel
Creators: name: Hoffmann, Julius
Publisher: name: unkn
Year: 2021

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 49, 1893
Spectroscopy, docking and molecular dynamics studies on the interaction between cis and trans palladium-alanine complexes with calf-thymus DNA and antitumor activities
Creators: name: Izadyar, Asma
name: Mansouri-Torshizi, Hassan
name: Dehghanian, Effat
name: Shahraki, Somaye
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: The present article investigates whether the cis and trans isomers of the same compound affect their antitumor and DNA-binding properties. Thus, we have synthesized cis-[Pd(L-Ala)2] (I) and trans-[Pd(L-Ala)2] (II) (Ala = L-alanine) complexes by modifications to improve the reported procedure. Cytotoxicity tests of these two isomers along with carboplatin (as a known drug) against MCF-7 and HCT-116 (as cancerous) and MCF10A and CCD-841 (as normal cell lines) were performed under the same experimental conditions. The results follow the sequence I > II > carboplatin for both cell lines. DNA-binding studies were carried out in a medium similar to that of physiological conditions (pH = 7 and 0.02 M NaCl). Results of UV–vis absorption provides apparent binding constant, Kapp, and midpoint transition of native CT-DNA to refolded structure, L1/2, suggesting interaction at quite low concentrations of these metal complexes. Fluorescence emission intensity of the CT-DNA-EB system demonstrates static quenching predominates in the binding process. Moreover, negative values of ΔH0 and ΔS0 suggested that the hydrogen bonds and van der Waals forces are the interaction forces between the complexes with the CT-DNA groove. Other studies include gel electrophoresis, viscosity experiments, partition coefficient, computational energy minimization, molecular docking and molecular dynamics simulations. All these studies indicate that the cis isomer has better interaction towards CT-DNA and are in accord with fluorescence, UV–vis and cytotoxicity studies. The present work gives valuable indications for further design of cis and trans metal-based isomers as potential anticancer agents.