cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Enterovirus 71 infection of human airway organoids reveals VP1-145 as a viral infectivity determinant
Creators: name: van der Sanden, Sabine M. G.
name: Sachs, Norman
name: M. Koekkoek, Sylvie
name: Koen, Gerrit
name: Pajkrt, Dasja
name: Clevers, Hans
name: Wolthers, Katja C.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Human enteroviruses frequently cause severe diseases in children. Human enteroviruses are transmitted via the fecal–oral route and respiratory droplets, and primary replication occurs in the gastro-intestinal and respiratory tracts; however, how enteroviruses infect these sites is largely unknown. Human intestinal organoids have recently proven to be valuable tools for studying enterovirus–host interactions in the intestinal tract. In this study, we demonstrated the susceptibility of a newly developed human airway organoid model for enterovirus 71 (EV71) infection. We showed for the first time in a human physiological model that EV71 replication kinetics are strain-dependent. A glutamine at position 145 of the VP1 capsid protein was identified as a key determinant of infectivity, and residues VP1-98K and VP1-104D were identified as potential infectivity markers. The results from this study provide new insights into EV71 infectivity in the human airway epithelia and demonstrate the value of organoid technology for virus research.
Substitution of D701N in the PB2 protein could enhance the viral replication and pathogenicity of Eurasian avian-like H1N1 swine influenza viruses
Creators: name: Liu, Suli
name: Zhu, Wenfei
name: Feng, Zhaomin
name: Gao, Rongbao
name: Guo, Junfeng
name: Li, Xiyan
name: Liu, Jia
name: Wang, Dayan
name: Shu, Yuelong
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Eurasian avian-like H1N1 (EA H1N1) swine influenza viruses (SIVs) have become predominant in pig populations in China and have recently been reported to have the most potential to raise the next pandemic in humans. The mutation D701N in the PB2 protein, which accounts for 31% of H1N1 SIVs, has previously been shown to contribute to the adaptation of the highly pathogenic H5N1 or H7N7 avian influenza viruses in mammals. However, little is known of the effects of this substitution on the EA H1N1 viruses. Herein, we investigated the contributions of 701N in the PB2 protein to an EA H1N1 SIV (A/Hunan/42443/2015(H1N1), HuN EA-H1N1), which had 701D in the PB2 protein. Our results found that viral polymerase activity, viral replication, and pathogenicity in mice were indeed enhanced due to the introduction of 701N into the PB2 protein, and the increased viral growth was partly mediated by the host factor importin-α7. Thus, substantial attention should be paid to the D701N mutation in pig populations.
Xanthium spinosum L.
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Xanthium
Xanthium spinosum

description: Xanthium spinosum L.
Dornige Spitzklette
Art ISFS: 455100 Checklist: 1050610 Asteraceae Xanthium Xanthium spinosum L.
Zusammenfassung
Artbeschreibung (nach Lauber & al. 2018): 15-80 cm hoch, verzweigt. Stängel kurz behaart, gelblich, unter den Blättern mit 1,5-2,5 cm langen, 3teiligen gelben Stacheln. Blätter 3lappig oder ungeteilt, ganzrandig, unterseits weissfilzig. Blütenköpfe eingeschlechtig, männliche 4-5 mm lang, gelblich, vielblütig, einzeln oder geknäuelt in oberen Blattwinkeln, weibliche 8-15 mm lang in tieferen Blattwinkeln, mit nur 2 kronenlosen Blüten, ihre Hülle wie bei X. strumarium.
Blütezeit (nach Lauber & al. 2018): 7-9
Standort und Verbreitung in der Schweiz (nach Lauber & al. 2018): Hecken, Schuttplätze / kollin / Vereinzelt VS, VD, SG, SH, AG
Verbreitung global (nach Lauber & al. 2018): Ursprünglich südamerikanisch
Ökologische Zeigerwerte (nach Landolt & al. 2010) 235+44 + 4.t.2n=36
Ökologie
Lebensform Therophyt
Lebensraum Lebensraumnach Delarze & al. 2015
7.1.4 - Einjährige Ruderalflur (Sisymbrion)
fett Dominante Art, welche das Aussehen des Lebensraumes mitprägt Charakterart Weniger strikt an den Lebensraum gebundene Art
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl Fmässig trockenLichtzahl LhellSalzzeichen1Reaktionszahl Rschwach sauer bis neutral (pH 4.5-7.5)Temperaturzahl Twarm-kollinNährstoffzahl Nsehr nährstoffreich bis überdüngtKontinentalitätszahl Ksubkontinental (niedrige relative Luftfeuchtigkeit, grosse Temperaturschwankungen, eher kalte Winter)
Nomenklatur
Gültiger Name (Checklist 2017):Xanthium spinosumL.
Volksname Deutscher Name: Dornige Spitzklette Nom français: Lampourde épineuse Nome italiano: Nappola spinosa
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Xanthium spinosum L.Checklist 2017455100=Xanthium spinosum L.Flora Helvetica 20012091=Xanthium spinosum L.Flora Helvetica 20122083=Xanthium spinosum L.Flora Helvetica 20182083=Xanthium spinosum L.Index synonymique 1996455100=Xanthium spinosum L.Landolt 19773028=Xanthium spinosum L.Landolt 19912440=Xanthium spinosum L.SISF/ISFS 2455100=Xanthium spinosum L.Welten & Sutter 19821775
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Status Indigenat: Neophyt: nach der Entdeckung von Amerika in der Region aufgetreten (nach 1500)
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
Responsabilità sanitaria e COVID-19: scenari di una possibile pandemia giudiziaria e risposte per prevenirla
Creators: name: Izzo, Umberto
Publisher: name: Zenodo
Year: 2020
Subjects: Responsabilità civile
Pandemia
COVID-19
Piani di indennizzo no-fault
Responsabilità sanitaria
Medicina delle catastrofi
Civil liability
Pandemic
No-Fault Compensation Plan
Health Providers Liability
Disaster Medicine

description: This paper analyzes the possible compensation scenarios following the advent of the health emergency caused by the COVID-19 pandemic, verifying to what extent the civil liability enforced against health professionals and health structures can be effec-tive in granting compensation for the alleged damage by patients who did not receive adequate treatment following the outbreak of the pandemic during the lockdown pe-riod (March-May 2020). Speculating on the history and outcomes of the HIV-tainted blood litigation, the work further addresses to what extent the model of civil liability of State and Regions – which seemed to disregard precise and detailed measures pre-viously issued to allow the National Health system as a whole to effectively handle the outburst of a flu pandemic – may polarize the litigation promoted by the victims of COVID in the first wave of the pandemic. In conclusion, it is suggested to consider the establishment of a State fund to compensate COVID victims tailored at settling the cases of this possible litigation, in order to avoid the inconveniences caused by 210/1992 law, with which the State provided to indemnify subjects irreversibly dam-aged by the administration of HIV and hepatitis-tainted blood and blood products. Questo paper esplora i possibili scenari risarcitori conseguenti all’avvento dell’emergenza sanitaria determinata dalla pandemia del COVID-19, verificando in che misura la responsabilità civile azionata nei confronti di operatori sanitari e struttu-re possa risultare effettiva nel garantire il risarcimento del danno lamentato da quanti non abbiano potuto ricevere cure adeguate in esito al deflagrare della pandemia duran-te il periodo del lockdown (marzo-maggio 2020). Ragionando sul contenzioso seguito al caso del sangue infetto, si verifica come il modello della responsabilità civile dello Stato e delle Regioni, che sembrano aver disatteso precisi e dettagliati provvedimenti emanati per consentire al sistema sanitario nazionale nel suo complesso di essere pronto a gestire in modo ottimale l’avvento di una pandemia influenzale, possa pola-rizzare il contenzioso promosso dalle vittime del COVID nella prima ondata della pandemia. In conclusione, si propone di considerare l’istituzione di un fondo destina-to alla compensazione delle vittime che agisca su base transattiva, evitando di determi-nare gli inconvenienti seguiti alla emanazione della legge 210/1992 con la quale lo Sta-to ha provveduto a indennizzare i soggetti danneggiati in modo irreversibile dalla somministrazione di sangue ed emoderivati infetti.
Active sero-survey for European bat lyssavirus type-1 circulation in North African insectivorous bats
Creators: name: Serra-Cobo, Jordi
name: López-Roig, Marc
name: Lavenir, Rachel
name: Abdelatif, Elbia
name: Boucekkine, Wahida
name: Elharrak, Mehdi
name: Harif, Bachir
name: Ayachi, Sehhar El
name: Salama, Akram Ahmed
name: Nayel, Mohamed A.
name: Elsify, Ahmed
name: Rashedy, Sameh G. El
name: De Benedictis, Paola
name: Mutinelli, Franco
name: Zecchin, Barbara
name: Scaravelli, Dino
name: Balhoul, Chokri
name: Zaghawa, Ahmed
name: Hassan, Hany Youssef
name: Zaghloul, Ahmed Hamed
name: Bourhy, Hervé
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Science Policy

description: Active sero-survey for European bat lyssavirus type-1 circulation in North African insectivorous bats
Xanthium strumarium
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Xanthium
Xanthium strumarium

description: Xanthium strumarium aggr.
Kropf-Spitzklette
Art ISFS: 455250 Checklist: 1050615 Asteraceae Xanthium Xanthium strumarium aggr. Enthält: Xanthium orientale L. Xanthium strumarium L.
ZusammenfassungKEINE ANGABE
Ökologie
Lebensraum Lebensraumnach Delarze & al. 2015
KEINE ANGABE
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl F--Lichtzahl L--Salzzeichen--Reaktionszahl R--Temperaturzahl T--Nährstoffzahl N--Kontinentalitätszahl K--
Nomenklatur
Gültiger Name (Checklist 2017):Xanthium strumariumaggr.
Volksname Deutscher Name: Kropf-Spitzklette Nom français: Lampourde ordinaire Nome italiano: Nappola minore
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Xanthium strumarium aggr.Checklist 2017455250
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Kommentare aus der Checklist 2017 Gegenüber SISF-2 neu definiertes Aggregat. Checklist
Status Indigenat: Neophyt: nach der Entdeckung von Amerika in der Region aufgetreten (nach 1500)
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
Reducing the prevalence of compassion fatigue among emergency department advanced practice providers by increasing awareness
Creators: name: Pathak, Vaibhavee
Publisher: name: No Publisher Supplied
Year: 2020

description: Purpose of Project: The purpose of this Doctoral project was to reduce the level of compassion fatigue suffered by the Emergency Department Advances Practice Providers. Healthcare workers especially the ones that practice in high-stress level areas such as an emergency department are at great risk for developing compassion fatigue (Bellolio et al., 2014). A concern is providers managing care for variety of critical and non-acute patients while bottling up their emotional are at great risk for suffering a negative consequences of compassion fatigue (Weilenmann et al. 2018). By increasing awareness of the concept, self-care activities and the available resources clinicians are likely to improve compassion satisfaction scores and reduce the effects of compassion fatigue (Dasan, Gohil, Cornelius & Taylor, 2015).Methodology: The project was carried out at two urban emergency departments located in the Northeast United States. A total of 11 out of 15 prospect participants took part in the study. This quasi-experimental study’s intervention included one-on-one interviews with the participants to increase awareness of the phenomena and informational pamphlets. The Compassion Fatigue/ Satisfaction Self-test was administrated as pre and post-test to evaluate the study findings. Results: This study found an improvement in participants compassion fatigue and satisfaction scores one- month after the intervention. Their answers collected during the interview will serve as tool to change practices and improve future studies. Implications for Practice: As supported by the literature review and this study finding, it can be concluded that all clinician can benefit from compassion fatigue awareness project.
In-situ microscopy investigation of floc development during coagulation-flocculation with chemical and natural coagulants
Creators: name: Nunes, Gustavo Santos
name: Silva, Kamila Jessie Sammarro
name: Freitas, Bárbara Luíza Souza
name: Belini, Valdinei Luís
name: Sabogal-Paz, Lyda Patricia
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: This study aimed to include in-situ microscopy in the analysis of floc development during coagulation-flocculation for drinking water treatment. To this end, jartest series were carried out for natural and synthetic waters using aluminum sulfate, sulfate chloride, ferric chloride, and Opuntia sp. as coagulants. Coagulation under optimized conditions was monitored by an in-situ microscope in conjunction with image analysis. Obtained results enabled some insights on the coagulation process. Images captured different stages of initial floc development, including flocs exhibiting heterogeneous, branched, and irregular surface structures. From image analysis, wide distributions of flocculated particle sizes were found for both natural (19–15834 μm) and synthetic water (19–21607 μm), suggesting the occurrence collisions by adhesion and transport between particles, thus influencing floc formation rates depending on the medium. Average size and number of flocs, as determined by the image analysis algorithm as a function of the time, showed inverse correlation of floc growth with water clarification. The microscopic images also illustrated how different coagulants in different water sources undergo breaking through fragmentation or erosion. Our findings also highlight the importance of investigating additional aspects that involve conditions of mixing, development, breaking, regrouping, and resistance of flocs.
Xeranthemum annuum L.
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Xeranthemum
Xeranthemum annuum

description: Xeranthemum annuum L.
Einjährige Strohblume
Art ISFS: 455300 Checklist: 1050630 Asteraceae Xeranthemum Xeranthemum annuum L.
Zusammenfassung
Artbeschreibung (nach Lauber & al. 2018): Ähnlich wie X. inapertum, aber schon unter der Mitte verzweigt, Blätter höchstens 3 cm lang, Köpfe 100-120 blütig, Durchmesser zur Blütezeit 2,5- 4 cm, Blüten hellviolett, Hüllblätter zur Blütezeit ausgebreitet, die innersten mehr als doppelt so lang wie die äusseren, Zungenblüten vortäuschend. Früchte 3-4,5 mm, Pappusschuppen 2-3 mm lang.
Blütezeit (nach Lauber & al. 2018): 6-7
Standort und Verbreitung in der Schweiz (nach Lauber & al. 2018): Ödland, selten adventiv oder aus Gärten verwildert / kollin /
Verbreitung global (nach Lauber & al. 2018): Ostmediterran
Ökologische Zeigerwerte (nach Landolt & al. 2010) 132-455.t.2n=12
Ökologie
Lebensform Therophyt
Lebensraum Lebensraumnach Delarze & al. 2015
KEINE ANGABE
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl Fsehr trockenLichtzahl LhellSalzzeichen--Reaktionszahl Rschwach sauer bis neutral (pH 4.5-7.5)Temperaturzahl Tsehr warm-kollin (nur an wärmsten Stellen, Hauptverbreitung in Südeuropa)Nährstoffzahl NnährstoffarmKontinentalitätszahl Kkontinental (sehr niedrige Luftfeuchtigkeit, sehr grosse Temperaturschwankungen, kalte Winter)
Nomenklatur
Gültiger Name (Checklist 2017):Xeranthemum annuumL.
Volksname Deutscher Name: Einjährige Strohblume, Einjährige Spreublume Nom français: Xéranthème annuel Nome italiano: Perpetuini maggiori
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Xeranthemum annuum L.Checklist 2017455300=Xeranthemum annuum L.Flora Helvetica 20012191=Xeranthemum annuum L.Flora Helvetica 20122183=Xeranthemum annuum L.Flora Helvetica 20182183=Xeranthemum annuum L.Index synonymique 1996455300=Xeranthemum annuum L.Landolt 19772948=Xeranthemum annuum L.SISF/ISFS 2455300
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Status Indigenat: Neophyt: nach der Entdeckung von Amerika in der Region aufgetreten (nach 1500)
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
Xeranthemum cylindraceum Sm.
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Xeranthemum
Xeranthemum cylindraceum

description: Xeranthemum cylindraceum Sm.
Art ISFS: 455400 Checklist: 1050640 Asteraceae Xeranthemum Xeranthemum cylindraceum Sm.
ZusammenfassungKEINE ANGABE
Ökologie
Lebensraum Lebensraumnach Delarze & al. 2015
KEINE ANGABE
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl F--Lichtzahl L--Salzzeichen--Reaktionszahl R--Temperaturzahl T--Nährstoffzahl N--Kontinentalitätszahl K--
Nomenklatur
Gültiger Name (Checklist 2017):Xeranthemum cylindraceumSm.
Volksname
Deutscher Name: -- Nom français: -- Nome italiano: --
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Xeranthemum cylindraceum Sm.Checklist 2017455400=Xeranthemum cylindraceum Sm.Index synonymique 1996455400=Xeranthemum cylindraceum Sm.SISF/ISFS 2455400
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Status Indigenat: -
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
title: Η δυναμική ένταξη του LNG στην αγορά, η χρήση του στην ναυτιλία και οι τερματικοί σταθμοί στην Ελλάδα
title: The dynamic integration of LNG in the market, its use in marine industry and the terminal stations in Greece
Creators: name: Σαβα Ντομενικο
Publisher: name: Technical University of Crete
Year: 2022

description: Καθώς η παγκόσμια ζήτηση για ενέργεια αυξάνεται συνεχώς με μεγάλο ρυθμό, οι παγκόσμιοι περιβαλλοντικοί κανονισμοί ωθούν την αγορά προς καθαρότερες μορφές ενέργειας και το φυσικό αέριο αποτελεί μια ικανοποιητική λύση αφού είναι ο καθαρότερος ορυκτός πόρος.
Παρά την αφθονία του το φυσικό αέριο δεν μπορεί να βρεθεί παντού και πολλές φορές είναι δύσκολο να μεταφερθεί σε μεγάλες αποστάσεις λόγω του μεγάλου όγκου που καταλαμβάνει. Η λύση σε αυτό το πρόβλημα είναι το LNG ή αλλιώς Υγροποιημένο Φυσικό Αέριο (ΥΦΑ), το οποίο σε αυτήν του την μορφή (υγρή) καταλαμβάνει έως 600 φορές λιγότερο όγκο σε σχέση με την αέρια.
Σε αυτήν την εργασία θα μελετηθούν τα βασικά χαρακτηριστικά του φυσικού αερίου στην αρχική του μορφή και θα γίνει περιγραφή της εφοδιαστικής αλυσίδας LNG από την φάση υγροποίησης μέχρι και την παράδοση του στον πελάτη. Θα αναλυθούν επίσης τα παγκόσμια στατιστικά και το περιβαλλοντικό αποτύπωμα του LNG καθώς και ο ρόλος του στην Ναυτιλία ως μεταφορικό καύσιμο.
Τέλος θα παρουσιαστούν οι μεγαλύτεροι τερματικοί σταθμοί LNG παγκοσμίως και θα μελετηθούν εκείνοι στην Ελλάδα καθώς και τα μελλοντικά σχέδια και οι προοπτικές που υπάρχουν στην χώρα μας για ανάπτυξη και άλλων υποδομών.
A novel SigB(Q225P) mutation in Staphylococcus aureus retains virulence but promotes biofilm formation
Creators: name: Liu, Hui
name: Shang, Weilong
name: Hu, Zhen
name: Zheng, Ying
name: Yuan, Jizhen
name: Hu, Qiwen
name: Peng, Huagang
name: Cai, Xinyu
name: Tan, Li
name: Li, Shu
name: Zhu, Junmin
name: Li, Ming
name: Hu, Xiaomei
name: Zhou, Renjie
name: Rao, Xiancai
name: Yang, Yi
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Staphylococcus aureus is an important pathogen that produces abundant virulence factors, which cause various diseases that burden human health worldwide. The stress response regulon called sigma factor B (SigB) is a well-characterized global regulator that is involved in the regulation of S. aureus virulence, pigmentation, and biofilm formation. However, the regulatory network upon SigB in S. aureus is incompletely described. Here, we identified a novel substitution mutation, SigB(Q225P), which contributed the nonpigmented phenotype of S. aureus. The S. aureus mutant carrying SigB(Q225P) substitution lacks staphyloxanthin, a key virulence factor in protecting bacteria from host-oxidant killing, but retains bacterial pathogenicity with pleiotropic alterations in virulence factors, resulting in similar lethality and abscess formation ability in animal models. We also reported the SigB(Q225P) promotion of biofilm formation in S. aureus. Real-time quantitative polymerase chain reaction (RT-qPCR) revealed that the expression of nuc gene, which encodes thermonuclease, was significantly downregulated, resulting in accumulation of eDNA in the biofilm of SigB(Q225P) mutant strain. LacZ reporter assay showed that SigB(Q225P) influenced the activity of nuc promoter. Furthermore, electrophoretic mobility shift assay (EMSA) and Bio-layer interferometry (BLI) assay revealed that both SigB and SigB(Q225P) proteins could directly bind to nuc gene promoter; however, the binding activity decreased for SigB(Q225P). Our data renewed the understanding of the relationship between S. aureus golden pigment and its virulence and suggested that a single substitution mutation in SigB might enhance the biofilm formation of S. aureus by directly downregulating nuc expression.
Long-term clinical outcomes of Zika-associated Guillain-Barré syndrome
Creators: name: Chang, Aileen Y.
name: Lynch, Rebecca
name: Martins, Karen
name: Encinales, Liliana
name: Bonfanti, Andrés Á. Cadena
name: Pacheco, Nelly
name: Reid, St. Patrick
name: Sarabia, Osvaldo E. Lara
name: Torres, Henry J. González
name: Castillo, Stella Mejia
name: Taborda, Onaldo Barrios
name: Gomez, Magda Alarcon
name: Duran, Brenda Guerra
name: Giraldo, Victor Martinez
name: Ospino, Angélica Benitez
name: Porras, Alexandra
name: Mendoza, Alejandro R.
name: Mantus, Grace
name: Li, Guangzhao
name: Peng, Jin
name: Kamalapathy, Priyanka
name: Echavez, Lil G. Avendaño
name: Dowd, Kimberly A.
name: Rengifo-Pardo, Monica
name: Barraza, Pedro Pablo
name: Hernàndez, Dennys Jiménez
name: Coba, Andrés González
name: De La Hoz Mendoza, Katya
name: Bethony, Jeffrey M.
name: Simon, Gary L.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Virology

description: Long-term clinical outcomes of Zika-associated Guillain-Barré syndrome
Concept for modelling the influence of electrode corrugation after calendering on stacking accuracy in battery cell production
Creators: name: Mayer, Dominik
name: Fleischer, Jürgen
Publisher: name: Elsevier
Year: 2021
Subjects: Modelling
Finite element method (FEM)
Manufacturing system

description: Due to the complex process chain in battery cell production, effects of processes on subsequent processes must be evaluated. As challenge in calendering electrodes, corrugation can be observed depending on adjusted parameters. To evaluate the corrugation with regard to the subsequent stacking process accuracy, a concept for modelling the process chain calendering - separation - single sheet stacking is presented. First, an experimental approach for modelling the calendering impact on the electrode sheet geometry after separation is suggested. Finally, a FEM simulation approach for the single sheet stacking process is presented, which is suitable to model impacts from previous processes.
Réseaux communautaires et communautés épistémiques dans le secteur culturel : le cas du Groupe de recherche sur la culture d’Ottawa
Creators: name: Doris, Julien
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2020
Subjects: Communautés épistémiques
Culture
Réseaux
Gouvernance

description: Le présent cahier de recherche s’intéresse aux formes et structures de la gouvernance du secteur culturel municipal. Il traite du cas très particulier de la Ville d’Ottawa qui occupe une place privilégiée, comparativement à d’autres municipalités de taille semblable au Canada, notamment en raison de sa forte concentration en ressources humaines, administratives, financières, matérielles et in extenso artistiques. L’étude de cas s’est concentrée sur le Groupe de Recherche sur la Culture à Ottawa (GRCO), une entité intersectorielle informelle créée sous l’initiative de la Ville d’Ottawa et qui vise à rassembler des acteurs gouvernementaux, privés, associatifs et universitaires afin de promouvoir une démarche commune de production d’indicateurs et de données en matière culturelle. En convoquant deux structures idéales-typiques de la gouvernance des politiques publiques, le présent texte soulève donc la contribution mais aussi les enjeux et les défis d’un tel collectif vis-à-vis de la gouvernance du secteur culturel ottavien. This research paper focuses on the forms and structures of governance in the municipal cultural sector. It emphases the very particular case of the City of Ottawa, which occupies a privileged position compared to other municipalities of similar size in Canada, particularly because of its high concentration of human, administrative, financial, material and artistic resources. The case study focuses on the Ottawa Cultural Research Group (OCGR), an informal intersectoral entity created at the initiative of the City of Ottawa and which intends to bring together government, private, associative and academic actors in order to promote a common approach to the production of indicators and data on cultural matters. By convening two ideal-typical structures of public policy governance, this paper raises the contribution but also the issues and challenges of such a collective action vis-à-vis the governance of the cultural sector in Ottawa.
Validation of a computer-based simulated patient surge drill for disaster education in the emergency department
Creators: name: Peterson, Keith
Publisher: name: No Publisher Supplied
Year: 2020

description: Purpose of Project: Disasters are occurring with an alarmingly growing frequency. With this, hospital staff is aware that there is a lack of a definitive training method to improve their education and response ability. This project demonstrated that using a disaster drill in the form of a drill simulator allowed for increased knowledge in disaster response.Methodology: A pre/post survey was performed using a nine-question adapted version of the Emergency Preparedness and Information Questionnaire (EPIQ) (Wisniewski, Dennik-Champion, & Peltier, 2004). Permission to use this was granted by one of the authors, Dr. James Peltier. The intervention was having the study participants under the Hospital Surge Evaluation Tool (US Department of Health and Human Services, 2017). Once the data was collected it was check for normality using the Shapiro-Wilk test. The data was found to not be normally distributed. With that finding the final analysis was preformed using the Wilcoxon Signed-Ranks Test. Results: It was found that there was a statistically significant increase in disaster knowledge over all nine questions asked. It can be concluded that a computer-based simulated patient surge drill is a valid teaching tool for disaster education in the emergency department. Implications for Practice: While there will not be a change in the daily clinical practice of the participants, it can be hoped that undergoing this drill will better prepare the participants for future events. Another aspect of clinical practice will be how and when resources are used during a surge event.
Implications of depth conversion on fault geometries and fault-risk assessment in the Smeaheia CO2 storage site, northern North Sea
Creators: name: Holden, N.
name: Skurtveit, E.
name: Braathen, A.
Publisher: name: Geological Society of London
Year: 2024
Subjects: classificationCode: 3705
subject: Geology
subject: FOS: Earth and related environmental sciences

description: Figure S1: thickness and time-structure map of the primary seal. Vertical axis is in ms TWT and vertical exaggeration is 3. Contour lines (increment 10 and 20 ms TWT, respectively) highlight orthogonal thickness variations and folding in the hanging wall of the VFZ1. Inset map shows the location of the surfaces.
Xerolekia speciosissima Anderb.
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Xerolekia
Xerolekia speciosissima

description: Xerolekia speciosissima (L.) Anderb.
Art ISFS: 455630 Checklist: 1046170 Asteraceae Xerolekia Xerolekia speciosissima (L.) Anderb.
ZusammenfassungKEINE ANGABE
Ökologie
Lebensraum Lebensraumnach Delarze & al. 2015
KEINE ANGABE
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl F--Lichtzahl L--Salzzeichen--Reaktionszahl R--Temperaturzahl T--Nährstoffzahl N--Kontinentalitätszahl K--
Nomenklatur
Gültiger Name (Checklist 2017):Xerolekia speciosissima(L.) Anderb.
Volksname
Deutscher Name: -- Nom français: -- Nome italiano: --
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Xerolekia speciosissima (L.) Anderb.Checklist 2017455630=Telekia speciosissima (L.) Less.Index synonymique 1996413900=Telekia speciosissima (L.) Less.SISF/ISFS 2413900
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Kommentare aus der Checklist 2017 Neuer Name (Gattungswechsel): Entspricht Telekia speciosissima (L.) Less. gemäss SISF-2. Checklist
Status Indigenat: -
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
Long-term clinical outcomes of Zika-associated Guillain-Barré syndrome
Creators: name: Chang, Aileen Y.
name: Lynch, Rebecca
name: Martins, Karen
name: Encinales, Liliana
name: Bonfanti, Andrés Á. Cadena
name: Pacheco, Nelly
name: Reid, St. Patrick
name: Sarabia, Osvaldo E. Lara
name: Torres, Henry J. González
name: Castillo, Stella Mejia
name: Taborda, Onaldo Barrios
name: Gomez, Magda Alarcon
name: Duran, Brenda Guerra
name: Giraldo, Victor Martinez
name: Ospino, Angélica Benitez
name: Porras, Alexandra
name: Mendoza, Alejandro R.
name: Mantus, Grace
name: Li, Guangzhao
name: Peng, Jin
name: Kamalapathy, Priyanka
name: Echavez, Lil G. Avendaño
name: A. Dowd, Kimberly
name: Rengifo-Pardo, Monica
name: Barraza, Pedro Pablo
name: Hernàndez, Dennys Jiménez
name: Coba, Andrés González
name: De La Hoz Mendoza, Katya
name: M. Bethony, Jeffrey
name: L. Simon, Gary
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Long-term clinical outcomes of Zika-associated Guillain-Barré syndrome
"A Woman Killed with Kindness"/Thomas Heywood: TEI Encoding of Robert Lawrence's 1963 edition
Creators: name: Monrós-Gaspar, Laura
Publisher: name: Zenodo
Year: 2017
Subjects: "TEI encoding", "early modern European theatre" "Heywood" "Woman"

description: An electronic edition, encoded by Laura Monrós-Gaspar (Universitat de València) in XML language following the Guidelines of the Text Encoding Initiative, of Robert Lawrence's 1963 edition of Thomas Heywood's play A Woman Killed with Kindness published in Early Seventeenth Century Drama (London: Dent ; New York: Dutton, 1963). This TEI edition is the basis of the HTML-PHP text published in the EMOTHE Digital Library  developed at the Universitat de València.
description: "Funded by Generalitat Valenciana (Spain) through project GVAICO2016-094"
Novel mechanical alignment and component fabrication for wavelength-selective optical switches
Creators: name: Wilkinson, Peter John
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: telecom
wavelength selective switches
LCoS
waveguide
single-mode fibre
metrology
passive alignment
self alignment
monolithic integration
kinematic
diffraction grating
optomechanics
athermalisation

description: Growing demand for internet bandwidth is driving an expansion of the optical switching infrastructure in the global telecom network. Two-dimensional free-space wavelength selective switches (WSSs) offer significantly increased integration over current linear WSS technology, providing a step change in switching capacity. The fabrication of two-dimensional WSSs presents significant optomechanical challenges. This thesis develops a range of novel alignment and fabrication techniques necessary to construct an experimental two-dimensional WSS system. Where necessary these techniques are further developed to enable the cost-effective volume manufacture of commercial switching products based on this technology. An overview of the role of a WSS in a wavelength-division-multiplexed telecom network is first provided. The operating principles and optical specification of the experimental WSS system are then described. The optomechanics require a unique combination of accuracy, stability and modularity, combined with the unique 2D architecture. An evaluation is made of the optomechanical techniques used for comparable systems. This demonstrates that three key areas of research are necessary to achieve the optomechanical requirements for the experimental WSS system. The first key task is the characterisation and development of the two-dimensional waveguide arrays required to realise the input and output ports. Both conventional single-mode fibres and waveguides fabricated with ultrafast-laser inscription (ULI) are investigated. The ULI waveguide technology is verified as an enabling technology for the volume manufacture of two-dimensional WSSs. The second key task is the development of passive alignment techniques for the micro-optical input-output assembly, using the precision afforded by mechanical parts fabricated with a ULI-etching process. These are shown to achieve micron-level accuracy without the need for external equipment. This has substantial implications for a range of fields beyond precision optics. The final task is the metrology, mounting and alignment of the bulk optics in the relay system. Novel kinematic and semikinematic mounting schemes are modelled, fabricated and experimentally verified. They then allow the WSS to be rapidly aligned to the required accuracy, enabling it to achieve optical performance superior to that of commercial products using conventional WSS technology.
description: Self-funded, with the fees paid by my employer, Roadmap Systems Ltd.
IMPACT OF IMPLEMENTING THE CHECKLIST PROCEDURE ON THE INCIDENCE OF SURGICAL SITE INFECTIONS IN CESAREAN SECTION WOMEN
Creators: name: G.BRAHIMI
name: H. OULD BABA ALI
name: S. AIT SEDDIK
name: S. AMRIT
Publisher: name: Zenodo
Year: 2024
Subjects: Surgical Site Infections - Caesarean Section - Impact Study - Patient Safety - Check-List, Risk Factors.

description: Abstract

Introduction: Surgical site infections (SSI) constitute a significant source of morbidity and mortality for cesarean parturients, with considerable impact on the healthcare system. Although the occurrence of SSIs depends on several factors, including those related to the patient, pregnancy complications, surgical procedure, and healthcare environment, these infections are largely preventable. The occurrence of SSIs may raise questions about the quality and safety of surgical interventions. Prevention of SSIs depends on a set of best practices to be applied before, during, and after surgical intervention. The aim of our study is to assess the impact of implementing the Pre- and Per-operative Safety Checklist on the incidence of SSIs in cesarean women.  Materials and Methods: This was a before-after evaluation study conducted in 2014 and 2015. Recruitment of parturients took place between February and April of each year, with the implementation of the checklist for SSI prevention after the first year of surveillance. Data collection was done in real-time (daily) with follow-up until Day 30. Data were entered and analyzed using Epi Info6 version 6.04 (CDC, Atlanta, USA), and multivariate analysis was performed using Epi Info 7 version 3.5.4. Results: A total of 611 cesarean sections were included, 311 in the pre-checklist study and 300 in the post-checklist study. The checklist was observed for 60% of procedures, i.e., 179 cesareans were performed with checklist application. A total of 66 cases of SSIs were recorded during the study period, of which 59 (89.4%) were superficial infections, 6 (9%) were deep SSIs, and 1 case was an organ or cavity infection (endometritis). The impact of prevention on reducing the incidence rate of SSIs was demonstrated in our study by applying a small number of effective measures to prevent infections, as listed on a Checklist for Patient Safety. A significant decrease in the incidence rate between the two study periods was achieved, dropping from 16.7% to 4.7% (an 86% reduction), and the risk of SSIs in cesarean parturients was reduced to 0.063 (OR = 0.063, 95% CI: [0.02-0.2], p <0.00001), meaning it is 15.9 times lower after implementing all prevention measures. The utility of such a tool reminding the application of best practices was thus demonstrated, with convincing results, which would also lead to healthcare cost savings. The Checklist should now be an integral part of daily work for teams, ensuring safer surgery.
Zinnia elegans Jacq.
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Zinnia
Zinnia elegans

description: Zinnia elegans Jacq.
Art ISFS: 455900 Checklist: 1050720 Asteraceae Zinnia Zinnia elegans Jacq.
ZusammenfassungKEINE ANGABE
Ökologie
Lebensraum Lebensraumnach Delarze & al. 2015
KEINE ANGABE
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl F--Lichtzahl L--Salzzeichen--Reaktionszahl R--Temperaturzahl T--Nährstoffzahl N--Kontinentalitätszahl K--
Nomenklatur
Gültiger Name (Checklist 2017):Zinnia elegansJacq.
Volksname
Deutscher Name: -- Nom français: -- Nome italiano: --
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Zinnia elegans Jacq.Checklist 2017455900
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Kommentare aus der Checklist 2017 Neues Taxon: Gegenüber SISF-2 neu aufgenommener Neophyt. Aus Kultur verwildert. Checklist
Status Indigenat: Kultivierter Neophyt: nach dem Jahr 1500 in der Schweiz aufgetreten
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): Nein
description: Published as part of Info Flora, 2021,
A neonatal mouse model of central nervous system infections caused by Coxsackievirus B5
Creators: name: Mao, Qunying
name: Hao, Xiaotian
name: Hu, Yalin
name: Du, Ruixiao
name: Lang, Shuhui
name: Bian, Lianlian
name: Gao, Fan
name: Yang, Ce
name: Cui, Bopei
name: Zhu, Fengcai
name: Shen, Lianzhong
name: Liang, Zhenglun
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: As one of the key members of the coxsackievirus B group, coxsackievirus B5 (CV-B5) can cause many central nervous system diseases, such as viral encephalitis, aseptic meningitis, and acute flaccid paralysis. Notably, epidemiological data indicate that outbreaks of CV-B5-associated central nervous system (CNS) diseases have been reported worldwide throughout history. In this study, which was conducted to promote CV-B5 vaccine and anti-virus drug research, a 3-day-old BALB/c mouse model was established using a CV-B5 clinical isolate (CV-B5/JS417) as the challenge strain. Mice challenged with CV-B5/JS417 exhibited a series of neural clinical symptoms and death with necrosis of neuronal cells in the cerebral cortex and the entire spinal cord, hindlimb muscles, and cardiomyocytes. The viral load of each tissue at various post-challenge time points suggested that CV-B5 replicated in the small intestine and was subsequently transmitted to various organs via viremia; the virus potentially entered the brain through the spinal axons, causing neuronal cell necrosis. In addition, this mouse model was used to evaluate the protective effect of a CV-B5 vaccine. The results indicated that both the inactivated CV-B5 vaccine and anti-CVB5 serum significantly protected mice from a lethal infection of CV-B5/JS417 by producing neutralizing antibodies. In summary, the first CV-B5 neonatal mouse model has been established and can sustain CNS infections in a manner similar to that observed in humans. This model will be a useful tool for studies on pathogenesis, vaccines, and anti-viral drug evaluations.
title: Μια ανασκόπηση στη σχεδιαστική προσέγγιση του Alvar Aalto. Φύση, Κλιματική Συνθήκη και Βιοκλιματικός Σχεδιασμός
title: A review of Alvar Aalto’s design approach nature, climate condition and bioclimatic design
Creators: name: Χατζηνικολη Θεκλα
Publisher: name: Technical University of Crete
Year: 2022

description: Ο Alvar Aalto υπήρξε ένας από τους σημαντικότερους αρχιτέκτονες του 20ου αιώνα. Η κύρια συμβολή του είναι ότι κατάφερε να ερμηνεύσει με επιτυχία τον μοντερνισμό, υπό μία ανθρωπιστική σκοπιά. Στόχος της παρούσας ερευνητικής εργασίας,  είναι να καταδειχθεί η σημασία της φύσης και των στοιχείων που προσφέρει στην αρχιτεκτονική, μέσα από την ανασκόπηση στη σχεδιαστική προσέγγιση του Alvar Aalto. Συγκεκριμένα, αναλύεται ο τρόπος που ο αρχιτέκτονας κατανοεί και αντιλαμβάνεται τους κανόνες της φύσης και ως εκ τούτου, ο τρόπος που την εντάσσει στο έργο του. Διατηρώντας πρωταρχικό παράγοντα στη συνθετική του σκέψη, η εναρμόνιση του εκάστοτε έργου του με το φυσικό περιβάλλον, αποτελεί συνειδητή απόφαση του Aalto. Στη μελέτη, αναλύονται πιθανοί τρόποι με τους οποίους η αρχιτεκτονική του, θα μπορούσε να συμβάλλει εποικοδομητικά στην ευρύτερη κατανόηση και εξέλιξη της επιστήμης της αρχιτεκτονικής, λαμβάνοντας υπόψη την προστασία και ανάδειξη του περιβάλλοντος.
title: Mit dem Mönch am Meer. Rezeption und Wirkung einer Virtual- Reality-Installation in der Alten Nationalgalerie Berlin: Eine Studie im Teilprojekt Visitor Journeys neu gedacht im Verbundprojekt museum4punkt0
Creators: name: Fendius, Katharina
name: Otte, Josefine
Publisher: name: Staatliche Museen zu Berlin
Year: 2021
Subjects: subject: Digitale Vermittlung
subject: Digitalisierung
subject: Museum
subject: Rezeptionsforschung
subject: Virtuelle Realität
subject: Qualitatives Interview
subject: Gruppenforschung
subject: 069
subject: 306
subject: 006

description: Die Staatlichen Museen zu Berlin entwickeln in ihrem Teilprojekt „Visitor Journeys neu gedacht“ des Verbundprojekts museum4punkt0 innovative digitale Medieneinsätze, die das Museumserlebnis vor, während und nach dem Besuch digital ergänzen. Das Gemälde Der Mönch am Meer von Caspar David Friedrich gehört zu den berühmtesten Werken der Sammlungen der Alten Nationalgalerie Berlin. Zwischen 2013 und 2016 wurde es umfassend restauriert und im Zuge dessen verschiedene Aspekte der Maltechnik und der Werkgenese eingehend erforscht. Mit Hilfe einer Virtual Reality-Installation, die vom 05.04.-30.06.2019 in der Alten Nationalgalerie aufgebaut und inszeniert wurde, sollte es Besucher*innen ermöglicht werden, in das Werk einzutauchen und in zweifacher Hinsicht zu verstehen: einerseits hinsichtlich der Szenerie, andererseits hinsichtlich des Malprozesses und der Grundbegriffe der Romantik im Œuvre Friedrichs. Das Teilprojekt „Visitor Journeys neu gedacht“ der Staatlichen Museen zu Berlin hat die Installation mit einer umfassenden Rezeptionsforschung begleitet. Ziel der Untersuchung war es, vertiefende Erkenntnisse hinsichtlich der Wirkung und der Rezeption digitaler Technologien sowie dem damit möglichst einhergehenden und erwünschten Mehrwert für den zielgruppenspezifischen Einsatz digitaler Technologien in Museen zu gewinnen. Während die Studie die Konzeption, Methodik und Auswertung der quantitatven und qualitativen Untersuchungen besschreibt, enthalten die drei zugehörigen Anlagen die genutzten Leitfäden für Fragebögen und Diskussionen mit den Fokusgruppen.
description: museum4punkt0 | Ergebnisse und Berichte aus dem Verbundprojekt