cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
PREBIOTIC POTENTIAL OF A WIDE SELECTION OF TUBERS, GRAINS, AND PULSES IN COMPARISON TO FRUCTO-OLIGOSACCHARIDE
Creators: name: Kazem, Ahmad Enosh
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Food sciences not elsewhere classified

description: The most common food and supplement prebiotic fiber is inulin – most commonly extracted from chicory root. Fructo-oligosaccharide (FOS) is a smaller version of inulin, both containing mainly fructose units with β-1,2 linkages. FOS/inulin has been used, and studied, as a prebiotic for decades. The potential of alternative prebiotics intrinsic in whole foods, such as in tubers, grains, vegetables, and pulses – the world’s most common staple crops – are not as commonly recognized as prebiotics, though have this potential if fermentable in the gut. If such alternative sources of prebiotic ingredients could be established it would allow for cheaper, possibly more effective, and more diverse food product development options beyond FOS/inulin. This study demonstrates the potential of tubers, grains, and pulses as prebiotics in relation to their in vitro human fecal fermentation rate, short chain fatty acid (SCFA) production, and microbiota indicators of alpha diversity and impact on key bacterial genera. Fecal samples were obtained from three diverse healthy human donors and used as the initial bacterial inoculum to simulate conditions in the human gut (colon). Substrates (n=35), after undergoing an upper gastrointestinal tract simulated digestion, were fermented by each individual donors’ inoculum separately, and measurements after 6, 12, and 24 h of fermentation were made on gas production, SCFA metabolite production, and microbiome composition. The results of this study establish high fermentability and potential prebiotic effects of dietary fibers from tubers, grains, and pulses. Whole foods, ground and cooked the same way, produced dietary fibers that were largely insoluble, but surprisingly fermentable with high SCFA levels, mostly slow fermentation profiles indicating high tolerability, and mostly promoting diverse microbiota responses compared to FOS. Generally, whole food fibers had higher fermentability than similar isolated fibers. Overall, the processing steps, such as atmospheric or pressure cooking, tested in some pulses did not detract, or add to, the prebiotic abilities of the substrates. Each food fiber substrate had unique effects on the gut microbiota parameters tested. Gut microbiome compositional responses to the same substrate varied significantly among the three donors, but notably SCFA metabolite responses were similar among donors.
A Call to Action for the Magnetic Shield Project
Creators: name: Kunferman, C.R.
Publisher: name: C.R. Kunferman
Year: 2025

description: "A dramatic shift is needed—a redirection of finances, attention, and resources, both digital and physical. If we do not solve the problems facing us here, we will never have the chance to face the challenges out there. This is a call to everyone: put down what you’re doing, shift your focus, and join us in learning, teaching, educating, and discussing one of the most critical features of our planet—the magnetic field that protects all life within it. Without it, we risk becoming just another red rock, wandering aimlessly, lifeless, around the Sun."
sj-pdf-1-jbx-10.1177_24725552211038379 – Supplemental material for Addressing Unusual Assay Variability with Robust Statistics
Creators: name: Haelewyn, Jason
name: Iversen, Philip W.
name: Weidner, Jeffrey R.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-jbx-10.1177_24725552211038379 for Addressing Unusual Assay Variability with Robust Statistics by Jason Haelewyn, Philip W. Iversen and Jeffrey R. Weidner in SLAS Discovery
Therapeutic role of physalin A in the pathogenesis of Graves’ orbitopathy
Creators: name: Kim, Eunjin
name: Kim, Ji-Young
name: Choi, Soo Hyun
name: Park, Hyun Young
name: Ko, JaeSang
name: Yoon, Jin Sook
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Graves’ orbitopathy (GO) is an autoimmune condition that causes serious ocular symptoms; its treatment strategies are limited. Physalin A is a phytosterol that has shown various therapeutic properties, including anti-inflammatory and anti-fibrotic effects. In this study, we investigated whether physalin A could inhibit inflammation, fibrosis, hyaluronan (hyaluronic acid) production, and adipogenesis, which are crucial to the pathogenesis of GO. Orbital tissue explants were obtained from patients with GO during orbital decompression surgery and healthy controls. Orbital fibroblasts (OFs) were isolated and treated with different concentrations of physalin A. Using western blot and ELISA analyses, we determined the effects of physalin A on OFs. Physalin A treatment suppressed the production of interleukin (IL)-1β-induced prostaglandin E2 (PGE2) and pro-inflammatory molecules, including cyclooxygenase (COX)-2, IL-6, IL-8, and intercellular adhesion molecule (ICAM)-1. We discovered that physalin A attenuated hyaluronan production induced by IL-1β or insulin-like growth factor (IGF)-1. Moreover, physalin A reduced lipid droplet formation and production of peroxisome proliferator activator (PPAR) γ, CCAAT-enhancer-binding protein (C/EBP) α, C/EBP β, sterol regulatory element binding protein (SREBP)-1, leptin, and adiponectin proteins. Physalin A suppressed the phosphorylation of extracellular signal-related kinase (ERK), nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB), and suppressor of mothers against decapentaplegic (SMAD) 2 signaling protein. Our study suggests that the major mechanisms by which physalin A suppresses GO include reducing inflammation, fibrosis, hyaluronan production, and adipogenesis in OFs. The findings of this study provide evidence of the therapeutic effect of physalin A in GO.
An integrative lipidomics and transcriptomics study revealing Bavachin and Icariin synergistically induce idiosyncratic liver injury
Creators: name: Li, Yingying
name: Cao, Bo
name: Lin, Mengmeng
name: Xu, Jing
name: Qi, Shuya
name: Wang, Jiabo
name: Xiao, Xiaohe
name: Li, Guohui
name: Li, Chunyu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Objectives: Reports of traditional Chinese medicine (TCM)-related liver injury have increased over recent years; however, identifying susceptibility-related components and biomarkers remains challenging due to the heterogeneous nature of TCM and idiosyncratic drug-induced liver injury (IDILI). Psoraleae Fructus (PF) and Epimedii Folium (EF), commonly found in TCM prescriptions, have been implicated in IDILI, but their constituents and underlying mechanisms are poorly understood. Methods: In this study, we identified bavachin (Bav) and icariin (Ica) as susceptibility components for IDILI in PF and EF using a TNF-α-mediated mouse model. Lipidomics and transcriptomics were used to investigate their related mechanism. Results: Liver biochemistry and histopathology analyses revealed that co-exposure to Bav, Ica, and a non-toxic dose of TNF-α prestimulation induced significant liver injury, while Bav and Ica alone did not. Lipidomics identified seven differentially abundant metabolites in the Bav/Ica/TNF-α group compared to the Ica/TNF-α or Bav/TNF-α groups, mainly enriched in alpha-linolenic acid (ALA), arachidonic acid (AA), and linoleic acid (LA) metabolic pathways. Additionally, transcriptomics revealed 49 differentially expressed genes (DEGs) in the Bav/TNF-α vs Bav/Ica/TNF-α and Ica/TNF-α vs Bav/Ica/TNF-α groups, primarily associated with the PI3K/AKT/mTOR signaling pathway and sphingolipid metabolism. Integrative lipidomics and transcriptomics analyses identified significant positive correlations between five differential metabolites (DMs) – PC (O-16:0_14:1), PG (22:1_20:3), PI (16:0_14:1), PS (18:0_19:2), and TG (17:0_18:2_22:5) – and ten DEGs – Nr0b2, Btbd19, Btg2, Fam222a, Fam83f, Gtse1, Anln, Gja4, Srrm4, and Zfp13. Conslusions: Collectively, these results suggest that alterations in intracellular metabolism and gene expression levels may contribute to the synergistic induction of IDILI by the incompatible pair Bav and Ica in the presence of TNF-α.
CAPACITATED NETWORK BASED PARKING MODELS UNDER MIXED TRAFFIC CONDITIONS
Creators: name: Lopez, Juan Esteban Suarez
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Civil engineering not elsewhere classified

description: New technologies such as electric vehicles, Autonomous vehicles and transportation platforms are changing the way humanity move in a dramatic way and cities around the world need to adjust to this rapid change brought by technology. One of the aspects more challenging for urban planners is the parking problem as the new increase or desire for these private technologies may increase traffic congestion and change the parking requirements across the city. For example, Electric vehicles will need parking places for both parking and charging and Autonomous vehicles could increase the congestion by making longer trips in order to search better parking alternatives. Thus, it becomes essential to have clear, precise and practical models for transportation engineers in order to better represent present and future scenarios including normal vehicles, autonomous vehicles and electric vehicles in the context of parking and traffic alike. Classical network model such as traffic assignment have been frequently used for this purpose although they do not take into account essential aspects of parking such as fixed capacities, variety of users and autonomous vehicles. In this work a new methodology for modelling parking for multi class traffic assignment is proposed including autonomous vehicles and hard capacity constraints. The proposed model is presented in the classical Cournot Game formulation based on path flows and in a new link-node formulation which states the traffic assignment problem in terms of link flows instead of path flows. This proposed model allows for the creation of a new algorithm which is more flexible to model requirements such as linear constrains among different players flows and take advantage of fast convergence of Linear programs in the literature and in practice. Also, this link node formulation is used to redefine the network capacity problem as a linear program making it more tractable and easier to calculate. Numerical examples are presented across this work to better exemplify its implications and characteristics. The present work will allow planners to have a clear methodology for modelling parking and traffic in the context of multiusers which can represent diverse characteristics as parking time or type of vehicles. This model will be modified to take into account AV and the necessary assumptions and discussion will be provided.
Inhibition of Slit3/Robo1 signaling alleviates osteoarthritis in mice by reducing abnormal H-type vessel formation in subchondral bone
Creators: name: Li, Peng
name: Feng, Kai
name: Zhan, Xuehua
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: The aberrant H-type vessel formation was found to be intimately linked to subchondral bone remodeling during osteoarthritis (OA) development. Herein, we investigated the role and mechanism of osteoblast-secreted slit guidance ligand 3 (Slit3) in H-type vessel formation during OA progression. Slit3 protein levels in subchondral bone samples of OA patients were detected. The isolated osteoblasts were transfected with Slit3 overexpression or knockdown plasmids, and their conditioned medium was cultured with endothelial progenitor cells (EPCs). The migration, tube formation, VEGF, and H-type vessel marker protein CD31 and endomucin (EMCN) levels in EPCs were accessed. The interactions between Slit3 and roundabout (Robo) family members were validated by Co-IP assay. Besides, whether the Slit3/Robo signaling affects the transforming growth factor β1 (TGF-β1)/SMADs pathway was determined. Additionally, sh-Slit3 was injected into OA mice, followed by the detection of articular cartilage degradation, subchondral bone remodeling, and H-type vessel formation. Slit3 was upregulated in subchondral bone tissues of OA patients. Slit3 overexpression in osteoblasts intensified the migration and H-type vessel formation of EPCs, while Slit3 knockdown showed the opposite results. Slit3 overexpression enhanced Robo1 protein level. Robo1 knockdown abrogated Slit3-mediated migration and H-type vessel formation in EPCs. Slit3 activated the TGF-β1/SMADs pathway in EPCs, which might be associated with H-type vessel formation in EPCs. Additionally, Slit3 silencing restrained articular cartilage degradation, aberrant subchondral bone formation, and H-type vessel formation in OA mice. Inhibition of Slit3/Robo1 signaling alleviates osteoarthritis in mice by reducing abnormal H-type vessel formation in the subchondral bone.
Clinical features, treatment, and outcome of nivolumab induced cholangitis
Creators: name: He, Yang
name: Fan, Zhiqiang
name: Sun, Wei
name: Ouyang, Linqi
name: Wang, Chunjiang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Background Cholangitis is an uncommon and severe adverse reaction of nivolumab with unclear clinical features. The purpose of this study was to investigate the clinicopathological features, imaging and treatment of nivolumab induced cholangitis. Methods Case reports, case series and clinical studies of nivolumab induced cholangitis were retrospectively analyzed by searching Chinese and English databases from January 1, 2017 to December 31, 2023. Results Thirty-eight patients entered the study. The median number of cycles of cholangitis onset was 7 cycles after administration (range 1, 28) and the median time was 11 days (range 78, 390). Abdominal pain (42.1%) and fever (18.4%) were the most important initial symptoms. Some patients (15.8%) showed elevated liver enzymes without any clinical symptoms. The median alkaline phosphatase level was 1721IU/L (range 126, 9118), and the median γ-glutamyltranspeptidase level was 829IU/L (range 104, 3442). Anti-nuclear antibodies, anti-mitochondrial antibodies and IgG4 typically show negative results. Imaging shows extrahepatic bile duct and intrahepatic bile duct dilation, hypertrophy, and stenosis. Liver biopsy and biliary tract biopsy mainly found CD8 inflammatory cell infiltration. Systemic steroids (84.2%) and ursodeoxycholic acid (UDCA) (34.2%) were administered, and 24 patients (63.2%) had poor to moderate response to steroids. Thirty-one patients (81.6%) improved and 7 patients (18.4%) did not improve. Conclusions Clinicians must remain vigilant for patients experiencing cholestasis while on nivolumab and should assess for cholangitis and carry out appropriate imaging tests. Considering the excellent efficacy of UCDA in cholangitis, steroids combined with UDCA may be a viable treatment option in cases where steroids are ineffective for cholangitis.
TupperwareEarth: Knowledge-Based Ontological Semantics for the "Internet of Kitchen Things"
Creators: name: Eom, Sangjun
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Networking and communications
Other engineering not elsewhere classified
Data communications

description: The term “IoT” has evolved to encompass a wide range of diffuse concepts, but the common thread among the myriad definitions has been the convergence of technology to bring advanced conveniences to our every day, but complicated, lives. A long-term focus of the Collaborative Robotics Lab, and a particular focus of many with interests in consumer assistance, has been the kitchen, which acts as the “nerve center” of the home in many cultures. However, despite the grand vision of revolutionizing the kitchen and improving our lifestyles with technology, what today’s IoT-integrated appliances and kitchen-focused conveniences offer is mainly limited to a remote control. While remote control is certainly convenient, it still requires human planning in both cognitive and physical loads in performing cooking activities. The goal of this thesis is to build a framework of the network of IoT-enabled kitchen appliances, TupperwareEarth for the “Internet of Kitchen Things” integrated with an inference engine that utilizes ontology as a knowledge database. From simple clustering of sensor data to recommender systems that employ crowd-sourced preference data, the cognitive burden is reduced with proactive suggestions to high-level queries based upon the current kitchen state. Through the progression of the studies in the “Internet of Kitchen Things,” TupperwareEarth aims to reduce human planning that involves both cognitive and physical loads of burden by inferring solutions to the activities of daily kitchen living using ontological semantics.
Integration of Active Control and Passive Compliance for Peg-and-hole Assembly
Creators: name: Li, Yuerong
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Mechanical engineering not elsewhere classified

description: This thesis provides a brief intro to the peg-and-hole problem and goes through two active and passive compliance strategies as well as the cases that the compliance center position is not ideal. A specific scenario of peg being gripped at an error angle due to large vision uncertainties is raised and studied. Such setup can lead to an off compliance center position relative to the peg and can happen in real life but has not been solved by previous approaches. A potential solution to it by combining active control and passive compliance is provided and analyzed. By using the force and torque feedback and the robot joint angle information, the compliance center for the above scenario could be estimated without vision feedback to by-pass the potential accuracy limitation of vision sensors. And a position control with reference determined in real-time by these sensors would be able to cancel out the majority of the effect caused by an off compliance center. Additional recommendations to future work on integration of active and passive compliance strategies and utilization of arbitrary compliance center positions are provided as well.
Reactivities Leading to Potential Chemical Repair of Sunlight-Induced DNA Damage: Mechanistic Studies of Cyclobutane Pyrimidine Dimer (CPD) Lesions under Alkaline Conditions
Creators: name: Chaturvedi, Ritu
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Biologically active molecules

description: Cyclobutane pyrimidine dimers (CPD) are the predominant DNA lesions formed upon exposure of this biopolymer to sunlight. Given the potentially dire biological consequences of DNA lesions, there is a need to fully characterize their behaviour, with an eye towards understanding their complete reactivity and as a possible means to detect and quantify their presence in the genome. The work described in this dissertation describes studies of the alkaline reactivity of CPD lesions generated within dinucleotide & polynucleotide strands. It was found that CPD-TpT is generally inert under alkaline conditions at room temperature, which is in agreement with earlier studies on alkaline hydrolysis of CPD-thymine and CPD-thymidine. However, a re-evaluation of the same reaction in the presence of 18O labelled water demonstrated that, similar to other UV-induced DNA lesions containing a saturated pyrimidine ring, CPD undergoes a water addition at the C4=O group of the nucleobase leading to the formation of a hemiaminal intermediate. This intermediate, however, does not lead to hydrolysis products and completely reverts to starting material under those same conditions. Moreover, the two C4=O groups present on 3′ and 5′-thymines in a CPD molecule show different chemical reactivities, with the 3′ C4=O group having greater affinity towards water addition as compared to the one on 5′ end, a fact reflected in different rates of exchange with the incoming nucleophile leading to the hemiaminal intermediate. The 18O labelling reaction was also investigated in CPD lesions generated within oligonucleotides to probe the cause of asymmetry between the 3′ vs 5′ C4=O groups; ultimately, it was determined that the asymmetric reactivity observed to occur between the two C4=O groups was an intrinsic property of the CPD molecule and did not arise as a result of asymmetry in a dinucleotide setting.
 In addition to the above studies, during the course of the investigation of the nucleophilic reactivity of CPD, a chemical reaction was observed leading to what appeared to be the rapid and total chemical reversal of CPD lesions to the original TpT (thymine-thymine dinucleotide)! This “repair” reaction occurred when CPD reacted with hydrazine, and appears facilitated by an inert atmosphere under which it rapidly proceeds to completion at room temperature.
title: Cruise ships and post-industrial port cities dynamics: an experimental sensory ethnographic approach to contemporary social, spatial and material interactions
Creators: name: Baixinho, Alexandra Duarte
Publisher: name: Goldsmiths, University of London
Year: 2016
Subjects: subject: visual sociology, mobilities, port cities, cruise ships, sensory ethnography, urban studies, post-industrial waterfronts

description: This thesis proposes an experimental sensory ethnographic approach to investigate the phenomenon of cruise ship tourism, from an ashore perspective, with cruise terminals and their surroundings as key nodes to my research. My focus is on how these aquamobilities – as I designate them - are performed in, interact with, and co-produce, the places visited. 

The main aim of this thesis is to contribute with liveliness (Back, 2012a; Back and and Puwar, 2012) to visual sociology scholarship, and to bring further knowledge on an understudied mobilities phenomenon. Walking, photographing, and doing sound recordings, were the main practices mobilized in the (uneven) engagement with field places, complemented with participant observation, interviews and informal conversations. My multi-sited fieldwork was based in Lisbon (for six months), Barcelona (for three months), and included shorter periods in Tilbury, Dover, Bergen/Oslo, and Le Havre. A set of visual and aural materials gathered along this journey, key along the research process are, also, part of this thesis, as alternative, evidential and evocative, paths to knowledge.

Theoretically, this work is framed by the new mobilities paradigm (Urry, 2000; Sheller and Urry, 2006b; Sheller, 2014), but further critical social sciences literature is mobilized, mostly with regards to post-industrial port cities and their waterfronts (Hoyle, 1994, 2000; Sieber, 1991; Chaline and Malta, 1994; Schubert, 2008), and to cruise ship tourism (Wood, 2002, 2006; Weaver, 2006; Chin, 2008; Clancy, 2008). Based on my empirical research, I will problematize the common understanding of infrastructures as fixed and immobile prevailing in the new mobilities paradigm (Hannam, Sheller, and Urry, 2006), arguing that cruise terminal infrastructures are rather elastic, dynamic, and partly mobile infrastructures.

This research foregrounds both the everyday practices and long-term transformations that cruise aquamobilities are bringing to post-industrial port-cities – through new social, material, spatial and temporal dynamics.
Comparison of Micro-Osteoperforation and Platelet-Rich Fibrin Methods in Accelerated Orthodontic Tooth Movement
Creators: name: Tyszkowski, Monika
Publisher: name: Archive of Orofacial Data Science
Year: 2024
Subjects: Accelerated Orthodontic Tooth Movement
Micro-Osteoperforation
Platelet-Rich Fibrin
Class II Malocclusion

description: AIM: The purpose of this thesis was to compare two methods of accelerated orthodontic tooth movement (OTM) in adults: Micro-osteoperforation (MOP) and platelet-rich fibrin (PRP/PRF) regarding the speed of canine retraction and other teeth OTM in terms of patient comfort measures.

METHODS: From over 3000 searches in different sources like PubMed, Cochrane Library, and Google Scholar, 21 peer-reviewed articles from 2015 to 2022 were selected. All the studies researched healthy, non-growing humans aged 16-40, diagnosed with Class II div 1 malocclusion with first premolar extraction or molar distalization or incisors crowding.

RESULTS: Both methods accelerated orthodontic tooth movement. The MOP method was slightly faster than the PRP/PRF method but more painful. There were a few reported side effects including root resorption, anchorage loss, and canine tipping more in the MOP studies. More MOPs placed less often were more effective. Higher platelet concentration injected more often had a better result. Both methods had inflammatory markers, particularly IL-beta elevated in the gingival crevicular fluid, which persisted longer in the MOPs. Gingival and plaque indexes showed clinically insignificant differences in MOP trials and were not measured in PRP/PRF studies.

CONCLUSION: Both experimented accelerated OTM methods can help to shorten adult treatment comfortably. Nevertheless, further studies on the PRP/PRF method, are needed.
description: Archive of Orofacial Data Science, Vol. 1 No. 1 (2024)
title: Philanthropy in Brazil and the UK: Wealth, Responsibility and the Pursuit of Social Change by Economic Elites
Creators: name: Sklair Correa, Jessica
Publisher: name: Goldsmiths, University of London
Year: 2017
Subjects: subject: Philanthropy, Elites, Corporate Social Responsibility, Brazil, UK

description: This thesis explores the philanthropy of economic elites in Brazil and the UK, positing their practice as part of a global elite philanthropic project. It argues that this project serves to further the aims of global capitalism, while attempting to mitigate the negative effects of capitalism’s fallout. Although the historical development of elite philanthropy in Brazil and the UK has been markedly different, accounting for technical differences in contemporary practice in these countries, recent decades have seen attempts to build an institutionalised philanthropic sector in Brazil based on British (and American) models. Today, the conceptual and ideological framework for the design of philanthropy in both countries is remarkably similar. In ethnographic enquiry into this common project, practices under the banners of ‘philanthrocapitalism’ and ‘strategic philanthropy’ emerge as the expression of deeply held ideologies of social change. These relate to the transposition of corporate strategies to philanthropy, to market-based solutions to social problems, and to attempts to eradicate poverty via better incorporation of the poor into existing economic structures. This enquiry, however, reveals how other aspects of elite experience also become entangled in the philanthropic project. In Brazil and the UK, elites use philanthropy to forge positive identities of wealth, and as a tool for managing inheritance. Among Brazilian family businesses, historical family narratives of philanthropy and corporate social responsibility aid business succession processes, in attempts to keep family firms – and family capital – intact with the passing of time. Finally, this thesis explores the work of philanthropic intermediaries, and the central role played by philanthropy advising and donor education programmes in shaping and disseminating philanthropic trends. Ethnography among intermediaries, however, reveals myriad ambiguities in their work. These serve to highlight elite philanthropy’s inability to confront the structures of inequality inherent to global capitalism, and the corresponding limits to its own project.
Glioneuronal heterotopia in the right middle cranial fossa
Creators: name: Russler-Germain, Emilie
name: Majumdar, Shamaita
name: Nguyen, Theresa
name: Hirose, Keiko
name: Yang, Peter H.
name: Mian, Ali
name: Dahiya, Sonika
Publisher: name: Free Neuropathology
Year: 2024
Subjects: Glioneuronal heterotopia
Intracranial extracerebral
Pigmented ocular epithelium
Choroid plexus

description: Free Neuropathology, Vol. 5 (2024)
sj-docx-5-hkj-10.1177_10249079211040971 – Supplemental material for Current situation and expectation of emergency medicine education for 8-year Doctor of Medicine degree program in China
Creators: name: Ge, Zengzheng
name: Feng, Shi
name: Liu, Xiangning
name: Guo, Shigong
name: Gao, Yanxia
name: Lu, Xin
name: Yu, Shiyuan
name: Zhao, Lina
name: Shi, Di
name: Liu, Jihai
name: Zhu, Huadong
name: Li, Yi
Publisher: name: SAGE Journals
Year: 2021
Subjects: Emergency Medicine

description: Supplemental material, sj-docx-5-hkj-10.1177_10249079211040971 for Current situation and expectation of emergency medicine education for 8-year Doctor of Medicine degree program in China by Zengzheng Ge, Shi Feng, Xiangning Liu, Shigong Guo, Yanxia Gao, Xin Lu, Shiyuan Yu, Lina Zhao, Di Shi, Jihai Liu, Huadong Zhu and Yi Li in Hong Kong Journal of Emergency Medicine
"Espacios de formación y comercialización agroecológica: lecciones aprendidas en la universidad central del ecuador" de Xavier León, Jaime Pazmiño, Ramiro Vivas & Darío Cepeda
Creators: name: Viteri, Xavier
Publisher: name: unknown
Year: 2024

description: El estudio aborda la integración del conocimiento académico con prácticas tradicionales, resaltando su impacto en el fortalecimiento de capacidades entre estudiantes, docentes y productores locales. Los resultados muestran avances en la creación de mercados agroecológicos inclusivos y sostenibles, a la vez que identifican desafíos como barreras logísticas, sostenibilidad económica y cambios culturales hacia un consumo responsable.
IoT DEVELOPMENT FOR HEALTHY INDEPENDENT LIVING
Creators: name: Greene, Shalom
Publisher: name: University of Kentucky
Year: 2017
Subjects: subject: Computer Engineering
subject: Electrical and Computer Engineering

description: The rise of internet connected devices has enabled the home with a vast amount of enhancements to make life more convenient. These internet connected devices can be used to form a community of devices known as the internet of things (IoT). There is great value in IoT devices to promote healthy independent living for older adults.

Fall-related injuries has been one of the leading causes of death in older adults. For example, every year more than a third of people over 65 in the U.S. experience a fall, of which up to 30 percent result in moderate to severe injury. Therefore, this thesis proposes an IoT-based fall detection system for smart home environments that not only to send out alerts, but also launches interaction models, such as voice assistance and camera monitoring. Such connectivity could allow older adults to interact with the system without concern of a learning curve. The proposed IoT-based fall detection system will enable family and caregivers to be immediately notified of the event and remotely monitor the individual. Integrated within a smart home environment, the proposed IoT-based fall detection system can improve the quality of life among older adults.

Along with the physical concerns of health, psychological stress is also a great concern among older adults. Stress has been linked to emotional and physical conditions such as depression, anxiety, heart attacks, stroke, etc. Increased susceptibility to stress may accelerate cognitive decline resulting in conversion of cognitively normal older adults to MCI (Mild Cognitive Impairment), and MCI to dementia. Thus, if stress can be measured, there can be countermeasures put in place to reduce stress and its negative effects on the psychological and physical health of older adults. This thesis presents a framework that can be used to collect and pre-process physiological data for the purpose of validating galvanic skin response (GSR), heart rate (HR), and emotional valence (EV) measurements against the cortisol and self-reporting benchmarks for stress detection. The results of this framework can be used for feature extraction to feed into a regression model for validating each combination of physiological measurement. Also, the potential of this framework to automate stress protocols like the Trier Social Stress Test (TSST) could pave the way for an IoT-based platform for automated stress detection and management.
Language And Abstraction In Egypt And Greece
Creators: name: Yaeger, Thomas
Publisher: name: Zenodo
Year: 2015
Subjects: Egypt, Greece, Phonology, Linguistics, Semantics, Abstraction, Martin Bernal, Black Athena,

description: A brief summary and analysis of Martin Bernal’s Black Athena Vol 3 (2006), from August 2013.
description: A draft of an appendix for a forthcoming book, 'Around Black Athena: The Origins of Graeco-Roman Culture', which is a record of a seminar series held at the Institute of Classical Studies, University of London, during the Spring Term of 1990. The seminars were organised by Amelie Kuhrt and John North.
Source code search for automatic bug localization
Creators: name: Akbar, Shayan Ali A
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Digital processor architectures
Other information and computing sciences not elsewhere classified

description: This dissertation advances the state-of-the-art in information retrieval (IR) based automatic bug localization for large software systems. We present techniques from three generations of IR based bug localization and compare their performances on our large and diverse bug localization dataset --- the Bugzbook dataset. The three generations span over fifteen years of research in mining software repositories for bug localization and include: (1) the generation of simple bag-of-words (BoW) based techniques, (2) the generation in which software-centric information such as bug and code change histories as well as structured information embedded in bug reports and code files are exploited to improve retrieval, and (3) the third and most recent generation in which order and semantic relationships between terms are modeled to improve the performance of bug localization systems. The dissertation also presents a novel technique called SCOR (Source Code Retrieval with Semantics and Order) which combines Markov Random Fields (MRF) based term-term ordering dependencies with semantic word vectors obtained from neural network based word embedding algorithms, such as word2vec, to better localize bugs in code files. The results presented in this dissertation show that while term-term ordering and semantic relationships significantly improve the performance when they are modeled separately in retrieval systems, the best precisions in retrieval are obtained when they are modeled together in a single retrieval system. We also show that the semantic representations of software terms learned by training the word embedding algorithm on a corpus of software repositories can be used to perform search in new software code repositories not present in the training corpus of the word embedding algorithm.
Leveraging Halogen Interactions for the Improved Performance of Reverse Osmosis Membranes
Creators: name: Toomey, Michael D
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Separation technologies
Polymers and plastics
Water treatment processes

description: Here, the quartz crystal microbalance with dissipation monitoring (QCM-D) is employed to explore the interaction of the various free oxidant species with condensed PA model membranes in order to improve our understanding of how the interaction with these species affects rates of membrane chlorination and alter membrane structure. Molecular-scale mass uptake and changes in the dissipative nature of the of the model membranes as measured by the QCM is correlated to performance changes in interfacially polymerized PA reverse osmosis (RO) membranes. Leveraging newly gained insights from these measured interactions, new strategies are explored to improve flux and chlorine resistance using novel membrane structure and chemistry.
Disentangling the Effects of Temperature, Clouds, and Gravity on K I doublet in L dwarfs
Creators: name: Baldelli, Alexandra J.
name: Suárez, Genaro
name: Cruz, Kelle L.
name: Faherty, Jacqueline K.
name: Rothermich, Austin
Publisher: name: arXiv
Year: 2025
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We investigate the effects of surface gravity, effective temperature, and cloudiness on the potassium doublet (\ion{K}{1}) at 1.17 μm in brown dwarf spectra. Using pseudo-Voigt profiles to fit the \ion{K}{1} doublet in Sonora Diamondback atmospheric model spectra, we find that gravity and cloudiness affect the spectra differently in mid to late-L dwarfs. The full-width at half-maximum (FWHM) is strongly correlated with surface gravity, while the maximum depth strongly correlates with cloudiness. This method allows us to separate the effects of clouds and surface gravity on the \ion{K}{1} 1.17 μm doublet. We also find that the FWHM and maximum depth of the doublet can help to estimate the effective temperature and surface gravity in early to mid-L dwarfs.
description: 4 pages, 1 figure, Code available at https://github.com/BDNYC/quantifying_sonora_KI_doublet
Additional file 1 of Women’s experiences of attempted suicide in the perinatal period (ASPEN-study) – a qualitative study
Creators: name: De Backer, Kaat
name: Pali, Alexandra
name: Challacombe, Fiona L.
name: Hildersley, Rosanna
name: Newburn, Mary
name: Silverio, Sergio A.
name: Sandall, Jane
name: Howard, Louise M.
name: Easter, Abigail
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1
EXAMINING THE EFFECTS OF AN ON-CAMPUS CULTURAL TRAINING COURSE COMBINED WITH FACULTY-LED, SHORT-TERM STUDY ABROAD EXPERIENCES ON UNDERGRADUATE STUDENTS’ CULTURAL INTELLIGENCE
Creators: name: Ingersoll, Lukas T
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Public health not elsewhere classified

description: As globalization continues to increase, the demand for culturally intelligent employees is central for navigating everyday intercultural business interactions. For college students preparing to enter the workforce, cultural intelligence is trained at universities through cultural training courses and study abroad experiences. Although cultural training courses and study abroad experiences are recognized as important factors in developing cultural intelligence, their effects are often assumed. Additionally, research indicates that international travel alone does not enhance a person’s overall cultural intelligence. This research examined a university program designed using Bandura’s Social Learning Theory to increase undergraduate students’ cultural intelligence through an on-campus cultural training course followed by a study abroad experience. Study 1 compared the effectiveness of a university program consisting of a cultural training course with a study abroad experience against a comparison control group. Multi-level modeling analyses suggest that students who participated in the cultural training course followed by a study abroad experience significantly increase in motivation, cognitive, metacognitive, and behavior CQ. Furthermore, interaction analyses examined the relationship between the two study groups, students’ self-assigned cultural development goals, the quality of their reflective journal entries, and an examination of any potential cultural mentor effects. None of these variables was associated with CQ growth. Study 2 compared two study abroad groups who either spent 3- or 6-weeks abroad after completing a shared cultural training course. Both groups experienced a statistically significant increase in all four CQ domains relative to a comparison group. When comparing the 3- and 6-week study abroad groups, there were no differences in motivation, cognitive, or behavior CQ; however, in metacognitive CQ, the 3-week group experienced a statistically significant increase compared to the 6-week group. No student-level predictors (age, gender identity, ethnicity, year in school, previous overseas experience, and grade point average) or program-level predictors (cultural mentor, number of countries visited) had a significant relationship with CQ development. These results demonstrate that a university intercultural development program that combines a cultural development training course with an instructor-led study abroad experience can help students improve their cultural intelligence, regardless of a student’s background, and that students can experience significant CQ growth in as little as 3-week abroad.
sj-pdf-1-ecl-10.1177_14687984211041389 - Supplemental material for Trilingualism and reading difficulty in a third (school) language: A case study of an at-risk child in French immersion
Creators: name: Petrescu, Maria Claudia
name: Helms-Park, Rena
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Education
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, sj-pdf-1-ecl-10.1177_14687984211041389 for Trilingualism and reading difficulty in a third (school) language: A case study of an at-risk child in French immersion by Maria Claudia Petrescu and Rena Helms-Park in Journal of Early Childhood Literacy
APPLYING MACHINE LEARNING TO OPTIMIZE SINTERED POWDER MICROSTRUCTURES FROM PHASE FIELD MODELING
Creators: name: BATABYAL, ARUNABHA
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Mechanical engineering not elsewhere classified

description: Sintering is a primary particulate manufacturing technology to provide densification and strength for ceramics and many metals. A persistent problem in this manufacturing technology has been to maintain the quality of the manufactured parts. This can be attributed to the various sources of uncertainty present during the manufacturing process. In this work, a two-particle phase-field model has been analyzed which simulates microstructure evolution during the solid-state sintering process. The sources of uncertainty have been considered as the two input parameters surface diffusivity and inter-particle distance. The response quantity of interest (QOI) has been selected as the size of the neck region that develops between the two particles. Two different cases with equal and unequal sized particles were studied. It was observed that the neck size increased with increasing surface diffusivity and decreased with increasing inter-particle distance irrespective of particle size. Sensitivity analysis found that the inter-particle distance has more influence on variation in neck size than that of surface diffusivity. The machine-learning algorithm Gaussian Process Regression was used to create the surrogate model of the QOI. Bayesian Optimization method was used to find optimal values of the input parameters. For equal-sized particles, optimization using Probability of Improvement provided optimal values of surface diffusivity and inter-particle distance as 23.8268 and 40.0001, respectively. The Expected Improvement as an acquisition function gave optimal values 23.9874 and 40.7428, respectively. For unequal sized particles, optimal design values from Probability of Improvement were 23.9700 and 33.3005 for surface diffusivity and inter-particle distance, respectively, while those from Expected Improvement were 23.9893 and 33.9627. The optimization results from the two different acquisition functions seemed to be in good agreement with each other. The results also validated the fact that surface diffusivity should be higher and inter-particle distance should be lower for achieving larger neck size and better mechanical properties of the material.
sj-doc-1-lap-10.1177_0094582X211029308 – Supplemental material for The Neodevelopmentalist Front and Mercosur under the PT Governments: The Rise and Fall of Multidimensional Regionalism
Creators: name: Berringer, Tatiana
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, sj-doc-1-lap-10.1177_0094582X211029308 for The Neodevelopmentalist Front and Mercosur under the PT Governments: The Rise and Fall of Multidimensional Regionalism by Tatiana Berringer in Latin American Perspectives
Supplementary files for "A dynamic model for Waddington's landscape accounting for cell-to-cell communication"
Creators: name: Merkt, Simon
name: Fuhrmann, Lara
name: Dudkin, Erika
name: Schlitzer, Andreas
name: Niethammer, Barbara
name: Hasenauer, Jan
Publisher: name: Zenodo
Year: 2024

description: Code for data analysis, model creation, simulation, parameter estimation, and plotting related to the manuscript "A dynamic model for Waddington’s landscape accounting for cell-to-cell communication".
Moving Research Methodology Toward Escience
Creators: name: Köhler, Thomas
name: Pscheida, Daniela
name: Scherp, Ansgar
name: Koschtial, Claudia
name: Felden, Carsten
name: Neumann, Jörg
Publisher: name: Zenodo
Year: 2016
Subjects: open innovation, eScience, research methodology, digital information management

description: Authors will present and discuss how open an innovation training platform is both: a working environment for the quality analyis of online data collections with data mining methods and a training environment with information, learning and exchange offers for digital information management.
sj-pdf-6-jsr-10.1177_10946705211035004 – Supplemental Material for Building Reflexivity Using Service Design Methods
Creators: name: Vink, Josina
name: Koskela-Huotari, Kaisa
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental Material, sj-pdf-6-jsr-10.1177_10946705211035004 for Building Reflexivity Using Service Design Methods by Josina Vink and Kaisa Koskela-Huotari in Journal of Service Research