cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Creation and Update of a Catalogue Raisonné in Wikidata (Lovis Corinth)
Creators: name: Raschka, Achim
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Wikidata
subject: Catalogue raisonné
subject: Werkverzeichnis
subject: Art history
subject: Lovis Corinth

description: Art History Loves Wiki 2025 – Collections, Archives & Research Data

Conference, Munich/online, January 10–12, 2005

Presentation
Hydrodynamical chemistry simulations of the SZ effect and the impacts from primordial non-Gaussianities
Creators: name: Pace, Francesco
name: Maio, Umberto
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The impacts of Compton scattering of hot cosmic gas with the cosmic microwave background radiation (Sunyaev-Zel'dovich effect, SZ) are consistently quantified in Gaussian and non-Gaussian scenarios, by means of 3D numerical, N-body, hydrodynamic simulations, including cooling, star formation, stellar evolution and metal pollution (He, C, O, Si, Fe, S, Mg, etc.) from different stellar phases, according to proper yields for individual metal species and mass-dependent stellar lifetimes. Light cones are built through the simulation outputs and samples of one hundred maps for the resulting temperature fluctuations are derived for both Gaussian and non-Gaussian primordial perturbations. From them, we estimate the possible changes due to early non-Gaussianities on: SZ maps, probability distribution functions, angular power spectra and corresponding bispectra. We find that the different growth of structures in the different cases induces significant spectral distortions only in models with large non-Gaussian parameters, $f_{\rm NL}$. In general, the overall trends are covered by the non-linear, baryonic evolution, whose feedback mechanisms tend to randomize the gas behaviour and homogenize its statistical features, quite independently from the background matter distribution. Deviations due to non-Gaussianity are almost undistinguishable for $f_{\rm NL}\lesssim 100$, remaining always at few-per-cent level, within the error bars of the Gaussian scenario. Rather extreme models with $f_{\rm NL}\sim1000$ present more substantial deviations from the Gaussian case, overcoming baryon contaminations and showing discrepancies up to a factor of a few in the spectral properties.
description: 10 pages, 4 figures, accepted for publication on MNRAS
Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels
Creators: name: Young, Janet
name: Shykind, Benjamin
name: Lane, Robert
name: Tonnes-Priddy, Lori
name: Ross, Joseph
name: Walker, Megan
name: Williams, Eleanor
name: Trask, Barbara
Publisher: name: Columbia University
Year: 2003
Subjects: subject: Gene expression
subject: Olfactory receptors
subject: Genetics
subject: FOS: Biological sciences
subject: Microbiology

description: Background: The olfactory receptor gene family is one of the largest in the mammalian genome. Previous computational analyses have identified approximately 1,500 mouse olfactory receptors, but experimental evidence confirming olfactory function is available for very few olfactory receptors. We therefore screened a mouse olfactory epithelium cDNA library to obtain olfactory receptor expressed sequence tags, providing evidence of olfactory function for many additional olfactory receptors, as well as identifying gene structure and putative promoter regions. Results: We identified more than 1,200 odorant receptor cDNAs representing more than 400 genes. Using real-time PCR to confirm expression level differences suggested by our screen, we find that transcript levels in the olfactory epithelium can differ between olfactory receptors by up to 300-fold. Differences for one gene pair are apparently due to both unequal numbers of expressing cells and unequal transcript levels per expressing cell. At least two-thirds of olfactory receptors exhibit multiple transcriptional variants, with alternative isoforms of both 5' and 3' untranslated regions. Some transcripts (5%) utilize splice sites within the coding region, contrary to the stereotyped olfactory receptor gene structure. Most atypical transcripts encode nonfunctional olfactory receptors, but can occasionally increase receptor diversity. Conclusions: Our cDNA collection confirms olfactory function of over one-third of the intact mouse olfactory receptors. Most of these genes were previously annotated as olfactory receptors based solely on sequence similarity. Our finding that different olfactory receptors have different expression levels is intriguing given the one-neuron, one-gene expression regime of olfactory receptors. We provide 5' untranslated region sequences and candidate promoter regions for more than 300 olfactory receptors, valuable resources for computational regulatory motif searches and for designing olfactory receptor microarrays and other experimental probes.
Additional file 1 of Leadership, governance and management for improving district capacity and performance: the case of USAID transform: primary health care
Creators: name: Desta, Binyam Fekadu
name: Azeb Abitew
name: Beshir, Ismael Ali
name: Mesele Damte Argaw
name: Sualiha Abdlkader
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Supportive supervision checklist categories
Additional file 1 of Knowledge, attitude, and practice regarding antibiotic use and resistance among medical students in Colombia: a cross-sectional descriptive study
Creators: name: Higuita-Gutiérrez, Luis Felipe
name: Villamil, Gustavo Eduardo Roncancio
name: Quiceno, Judy Natalia Jiménez
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1: Supplementary file questionnaire. Questionnaire “Survey on Knowledge, Attitudes, and Practices (KAP) related to antibiotics and bacterial resistance”. Questionnaire applied to students during the study.
KICHIK MAKTAB YOSHIDAGI O'QUVCHILARDA MANTIQIY FIKRLASHNI RIVOJLANTIRISHDA INNOVATSION YONDASHUVLAR
Creators: name: Alimova, Zarinahon
name: Muqimova, Mohichehra
name: Muqimova, Mohigul
name: Bobayeva, Ziyodaxon
Publisher: name: Zenodo
Year: 2025

description: Mazkur maqolada ta’lim sohasidagi yangiliklar va zamonaviy metodlar bolalarning mantiqiy fikrlash qobiliyatlarini rivojlantirishga katta etibor qaratiladi. Shuningdek, yosh avlodning muvaffaqiyati zamonaviy ta’limda mantiqiy fikrlash asoslari shakillantiriladi.
title: Glorreich-Triumphierendt-emporhangend-Sybillischer Gnaden-Schild, Bestrahlt von der auffgangnen Glücks Sonne; 1715
title: Das ist: Glückseelig-höchst erfreulicher Geburts-Tag, Deß Durchleuchtigisten deß H. Römischen Reichs Chur-Fürsten Maximilian Emmanuel Hertzog in Bayrn, [et]c. [et]c. Als an welchem die Haupt- und Residentz-Statt München Ihro Durchleucht, und gantzen Durchleuchtigisten Chur-Hauß zur glorreicher Ankunfft in Pomposer Solennitet gratulieret. So von einem Ihro Durchleucht Devotisten Lands-Vasallen angestimmet in jenem Thon: Fröhliche Posten, [et]c.
titleType: Subtitle
Creators: name: Ramppel, ...
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2014

description: Mutmaßl. Verf.: Ramppel
Prediction of enzyme function based on 3D templates of evolutionarily important amino acids
Creators: name: Kristensen, David
name: Ward, R Matthew
name: Lisewski, Andreas
name: Erdin, Serkan
name: Chen, Brian Y
name: Fofanov, Viacheslav
name: Kimmel, Marek
name: Kavraki, Lydia
name: Lichtarge, Olivier
Publisher: name: Columbia University
Year: 2008
Subjects: Genomics
Proteins--Structure
Biophysics
Molecular biology

description: Background: Structural genomics projects such as the Protein Structure Initiative (PSI) yield many new structures, but often these have no known molecular functions. One approach to recover this information is to use 3D templates – structure-function motifs that consist of a few functionally critical amino acids and may suggest functional similarity when geometrically matched to other structures. Since experimentally determined functional sites are not common enough to define 3D templates on a large scale, this work tests a computational strategy to select relevant residues for 3D templates. Results: Based on evolutionary information and heuristics, an Evolutionary Trace Annotation (ETA) pipeline built templates for 98 enzymes, half taken from the PSI, and sought matches in a non-redundant structure database. On average each template matched 2.7 distinct proteins, of which 2.0 share the first three Enzyme Commission digits as the template's enzyme of origin. In many cases (61%) a single most likely function could be predicted as the annotation with the most matches, and in these cases such a plurality vote identified the correct function with 87% accuracy. ETA was also found to be complementary to sequence homology-based annotations. When matches are required to both geometrically match the 3D template and to be sequence homologs found by BLAST or PSI-BLAST, the annotation accuracy is greater than either method alone, especially in the region of lower sequence identity where homology-based annotations are least reliable. Conclusion: These data suggest that knowledge of evolutionarily important residues improves functional annotation among distant enzyme homologs. Since, unlike other 3D template approaches, the ETA method bypasses the need for experimental knowledge of the catalytic mechanism, it should prove a useful, large scale, and general adjunct to combine with other methods to decipher protein function in the structural proteome.
Miscibility of blends of poly(methyl methacrylate) and oligodiols based on a bisphenol A nucleus and ethylene oxide or propylene oxide branches
Creators: name: Jaffrennou, B.
name: Soule, E. R.
name: Mechin, F.
name: Borrajo, J.
name: Pascault, J. P.
name: Williams, R. J. J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Cloud-point curves of blends of poly(methyl methacrylate) (PMMA) with a series of oligodiols based on a bisphenol A nucleus and short branches of poly(ethylene oxide) or poly(propylene oxide) (BPA-EO or BPA-PO), and with PEO and PPO oligomers, were obtained using a light transmission device. Experimental results were fitted with the Flory- Huggins model using an interaction parameter depending on both temperature and composition. For PMMA/PEO and PMMA/PPO blends, the miscibility increased when increasing the size of the diol, due to the significant decrease in the entropic and enthalpic terms contributing to the interaction parameter. This reflected the decrease in the selfassociation of solvent molecules and in the contribution of terminal OH groups to the mismatching of solubility parameters. For PMMA/BPA-EO blends, a decrease of the entropic contribution to the interaction parameter when increasing the size of the oligodiol was also found. However, the effect was counterbalanced by the opposite contribution of combinatorial terms leading to cloud-point curves located in approximately the same temperature range. For PMMA/BPA-PO blends, the interaction parameter exhibited a very low value. In this case, the effect of solvent size was much more important on combinatorial terms than on the interaction parameter, leading to an increase in miscibility when decreasing the oligodiol size. For short BPA-PO oligodiols no phase separation was observed. The entropic contribution of the interaction parameter exhibited an inverse relationship with the size of the oligodiols, independent of the nature of the chains bearing the hydroxyls and the type of OH groups (primary or secondary). This indicates that the degree of self-association of solvent molecules through their OH terminal groups, was mainly determined by their relative sizes.
description: Final published version available in Polymer (Elsevier), at http://www.sciencedirect.com/science/article/pii/S0032386104008080
Social correlates of cigarette smoking among Icelandic adolescents: A population-based cross-sectional study
Creators: name: Kristjansson, Alfgeir
name: Sigfusdottir, Inga
name: Allegrante, John P.
name: Helgason, Asgeir
Publisher: name: Columbia University
Year: 2008
Subjects: Teenagers
Smoking
Medical sciences
Social sciences--Research

description: Background: Previous research has shown that between 80 and 90 percent of adult smokers report having started smoking before 18 years of age. Several studies have revealed that multiple social factors influence the likelihood of smoking during adolescence, the period during which the onset of smoking usually occurs. To better understand the social mechanisms that influence adolescent smoking, we analyzed the relationship and relative importance of a broad spectrum of social variables in adolescent smoking in Iceland, a Nordic country with high per-capita income. Methods: We used cross-sectional data from 7,430 14- to 16 year-old students (approximately 81% of all Icelanders in these age cohorts) in the 2006 Youth in Iceland study. The Youth in Iceland studies are designed to investigate the role of several cognitive, behavioral, and social factors in the lives of adolescents, and the data collected are used to inform the design, implementation, and evaluation of substance use prevention programs that are being developed by Icelandic social scientists, policy makers, and practitioners. Results: Our analysis revealed that friends' smoking behavior and attitude toward smoking were strongly associated with adolescent smoking and other tobacco use, as well as alcohol consumption during the previous 30 days. Main protective factors were parent's perceived attitude toward smoking, the quantity of time spent with parents, absence of serious verbal conflict between parents and adolescents, and participation in physical activity. Family structure was related to adolescent smoking to a small extent, but other background factors were not. Conclusion: We conclude that multiple social factors are related to adolescent smoking. Parents and other primary preventive agents need to be informed about the complicated nature of the adolescent social world in order to maximize their impact.
Small-world networks of optical fiber lattices
Creators: name: Perakis, F.
name: Mattheakis, M.
name: Tsironis, G. P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We use a simple dynamical model and explore coherent dynamics of wavepackets in complex networks of optical fibers. We start from a symmetric lattice and through the application of a Monte-Carlo criterion we introduce structural disorder and deform the lattice into a small-world network regime. We investigate in the latter both structural (correlation length) as well as dynamical (diffusion exponent) properties and find that both exhibit a rapid crossover from the ordered to the fully random regime. For a critical value of the structural disorder parameter $ρ\approx 0.25$ transport changes from ballistic to sub-diffusive due to the creation strongly connected local clusters and channels of preferential transport in the small world regime.
Lateral motor column axons execute a ternary trajectory choice between limb and body tissues
Creators: name: Luria, Victor
name: Laufer, Edward M.
Publisher: name: Columbia University
Year: 2007
Subjects: subject: Spinal cord
subject: Neurons
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Cytology

description: Background: Neuronal topographic map formation requires appropriate selection of axonal trajectories at intermediate choice points prior to target innervation. Axons of neurons in the spinal cord lateral motor column (LMC), as defined by a transcription factor code, are thought to innervate limb target tissues exclusively. Axons of the medial and lateral LMC divisions appear to execute a binary decision at the base of the limb as they choose between ventral and dorsal limb trajectories. The cellular logic that guides motor axon trajectory choices into non-limb tissues such as the ventral flank remains unclear. Results: We determined the spinal cord motor column origin of motor nerves that innervate ventral flank tissues at hindlimb level. We found unexpectedly that a subset of medial LMC axons innervates ventral non-limb mesenchyme at hindlimb level, rather than entering ventral limb mesenchyme. We also found that in a conditional BmprIa mutant where all ventral hindlimb mesenchyme is converted to a dorsal identity, all medial LMC axons are redirected into the ventral flank, while lateral LMC axons innervate the bidorsal limb. Conclusion: We have found that medial LMC neurons innervate both ventral flank and limb targets. While normally only a subset of medial LMC axons innervate the flank, all are capable of doing so. Furthermore, LMC axons execute a ternary, rather than binary, choice at the base of the limb between ventral flank, ventral limb and dorsal limb trajectories. When making this choice, medial and lateral LMC axons exhibit different and asymmetric relative preferences for these three trajectories. These data redefine the LMC as a motor column that innervates both limb and body tissues.
Prefrontal control of the amygdala during real-time fMRI neurofeedback training of emotion regulation
Creators: name: Zotev, Vadim
name: Phillips, Raquel
name: Young, Kymberly D.
name: Drevets, Wayne C.
name: Bodurka, Jerzy
Publisher: name: arXiv
Year: 2013
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: We observed in a previous study (PLoS ONE 6:e24522) that the self-regulation of amygdala activity via real-time fMRI neurofeedback (rtfMRI-nf) with positive emotion induction was associated, in healthy participants, with an enhancement in the functional connectivity between the left amygdala (LA) and six regions of the prefrontal cortex. These regions included the left rostral anterior cingulate cortex (rACC), bilateral dorsomedial prefrontal cortex (DMPFC), bilateral superior frontal gyrus (SFG), and right medial frontopolar cortex (MFPC). Together with the LA, these six prefrontal regions thus formed the functional neuroanatomical network engaged during the rtfMRI-nf procedure. Here we perform a structural vector autoregression (SVAR) analysis of the effective connectivity for this network. The SVAR analysis demonstrates that the left rACC plays an important role during the rtfMRI-nf training, modulating the LA and the other network regions. According to the analysis, the rtfMRI-nf training leads to a significant enhancement in the time-lagged effect of the left rACC on the LA. The training is also accompanied by significant increases in the instantaneous (contemporaneous) effects of the left rACC on four other regions - the bilateral DMPFC, the right MFPC, and the left SFG. The instantaneous effects of the LA on the bilateral DMPFC are also significantly enhanced. Our results are consistent with a broad literature supporting the role of the rACC in emotion processing and regulation. Our analysis provides, for the first time, insights into the causal relationships within the network of regions engaged during the rtfMRI-nf procedure targeting the amygdala. It suggests that the rACC may constitute a promising target for rtfMRI-nf training along with the amygdala in patients with affective disorders, particularly posttraumatic stress disorder (PTSD).
description: 17 pages, 7 figures, submitted
Rates, amounts, and determinants of ambulatory blood pressure monitoring claim reimbursements among Medicare beneficiaries
Creators: name: Kent, Shia T.
name: Shimbo, Daichi
name: Huang, Lei
name: Diaz, Keith
name: Viera, Anthony J.
name: Kilgore, Meredith
name: Oparil, Suzanne
name: Muntner, Paul
Publisher: name: Columbia University
Year: 2014
Subjects: Ambulance service--Prospective payment
Medicare
Ambulatory blood pressure monitoring
Health services administration
Medical care
Medical sciences

description: Ambulatory blood pressure monitoring (ABPM) can be used to identify white coat hypertension and guide hypertensive treatment. We determined the percentage of ABPM claims submitted between 2007 and 2010 that were reimbursed. Among 1970 Medicare beneficiaries with submitted claims, ABPM was reimbursed for 93.8% of claims that had an International Classification of Diseases, Ninth Revision, diagnosis code of 796.2 (“elevated blood pressure reading without diagnosis of hypertension”) versus 28.5% of claims without this code. Among claims without an International Classification of Diseases, Ninth Revision, diagnosis code of 796.2 listed, those for the component (eg, recording, scanning analysis, physician review, reporting) versus full ABPM procedures and performed by institutional versus non–institutional providers were each more than two times as likely to be successfully reimbursed. Of the claims reimbursed, the median payment was $52.01 (25th–75th percentiles, $32.95–$64.98). In conclusion, educating providers on the ABPM claims reimbursement process and evaluation of Medicare reimbursement may increase the appropriate use of ABPM and improve patient care.
YSO accretion shocks: magnetic, chromospheric or stochastic flow effects can suppress fluctuations of X-ray emission
Creators: name: Matsakos, T.
name: Chièze, J. -P.
name: Stehlé, C.
name: González, M.
name: Ibgui, L.
name: de Sá, L.
name: Lanz, T.
name: Orlando, S.
name: Bonito, R.
name: Argiroffi, C.
name: Reale, F.
name: Peres, G.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context. Theoretical arguments and numerical simulations of radiative shocks produced by the impact of the accreting gas onto young stars predict quasi-periodic oscillations in the emitted radiation. However, observational data do not show evidence of such periodicity. Aims. We investigate whether physically plausible perturbations in the accretion column or in the chromosphere could disrupt the shock structure influencing the observability of the oscillatory behavior. Methods. We performed local 2D magneto-hydrodynamical simulations of an accretion shock impacting a chromosphere, taking optically thin radiation losses and thermal conduction into account. We investigated the effects of several perturbation types, such as clumps in the accretion stream or chromospheric fluctuations, and also explored a wide range of plasma-βvalues. Results. In the case of a weak magnetic field, the post-shock region shows chaotic motion and mixing, smoothing out the perturbations and retaining a global periodic signature. On the other hand, a strong magnetic field confines the plasma in flux tubes, which leads to the formation of fibrils that oscillate independently. Realistic values for the amplitude, length, and time scales of the perturbation are capable of bringing the fibril oscillations out of phase, suppressing the periodicity of the emission. Conclusions. The strength of a locally uniform magnetic field in YSO accretion shocks determines the structure of the post-shock region, namely, whether it will be somewhat homogeneous or if it will split up to form a collection of fibrils. In the second case, the size and shape of the fibrils is found to depend strongly on the plasma-βvalue but not on the perturbation type. Therefore, the actual value of the protostellar magnetic field is expected to play a critical role in the time dependence of the observable emission.
description: Accepted for publication in A&A
Development of Comprehensive Devnagari Numeral and Character Database for Offline Handwritten Character Recognition
Creators: name: Dongre, Vikas J.
name: Mankar, Vijay H.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In handwritten character recognition, benchmark database plays an important role in evaluating the performance of various algorithms and the results obtained by various researchers. In Devnagari script, there is lack of such official benchmark. This paper focuses on the generation of offline benchmark database for Devnagari handwritten numerals and characters. The present work generated 5137 and 20305 isolated samples for numeral and character database, respectively, from 750 writers of all ages, sex, education, and profession. The offline sample images are stored in TIFF image format as it occupies less memory. Also, the data is presented in binary level so that memory requirement is further reduced. It will facilitate research on handwriting recognition of Devnagari script through free access to the researchers.
description: 5 pages, 8 figures, journal paper
MPEC 2023-M19 : 2023 LF2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 LF2

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Effect of annealing on spinodally decomposed Co2CrAl grown via floating zone technique
Creators: name: Omar, Ahmad
name: Blum, Christian G. F.
name: Löser, Wolfgang
name: Büchner, Bernd
name: Wurmehl, Sabine
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Among the large class of Heusler compounds, Co2CrAl is predicted to be 100 % spin polarized and is hence, a potential candidate for application in spintronics. So far, the predicted properties have not been experimentally realized which may be attributed to the phase segregated nature of samples. This phase segregation is avoided using floating zone growth. However, the grown sample was found to have undergone phase transformation via spinodal decomposition at low temperatures. In the present work, thermal annealing has been done on the spinodally decomposed samples and its effect on microstructure, crystallographic structure and magnetic properties has been studied. Annealing experiments were done and analyzed in order to understand the extent of the solid state miscibility gap. With regards to the phase diagram, the two-phase regime was found to extend till 1000 °C. Even at 1250 °C, we are still inside the immiscibility region. The thermodynamic miscibility gap was thus found to exist until high temperatures and alternate routes might be required to obtain a single phase sample with the desired high spin polarization and Curie temperature in the Co-Cr-Al system.
description: 10 pages, 5 figures, 24 references, Proceedings of 17th International Conference on Crystal Growth and Epitaxy (ICCGE-17)
Synonymous site conservation in the HIV-1 genome
Creators: name: Mayrose, Itay
name: Stern, Adi
name: Burdelova, Ela
name: Sabo, Yosef
name: Laham-Karam, Nihay
name: Zamostiano, Rachel
name: Bacharach, Eran
name: Pupko, Tal
Publisher: name: Columbia University
Year: 2013
Subjects: subject: HIV (Viruses)
subject: Genomics
subject: Genetics
subject: FOS: Biological sciences
subject: Biology

description: Background: Synonymous or silent mutations are usually thought to evolve neutrally. However, accumulating recent evidence has demonstrated that silent mutations may destabilize RNA structures or disrupt cis regulatory motifs superimposed on coding sequences. Such observations suggest the existence of stretches of codon sites that are evolutionary conserved at both DNA-RNA and protein levels. Such stretches may point to functionally important regions within protein coding sequences not necessarily reflecting functional constraints on the amino-acid sequence. The HIV-1 genome is highly compact, and often harbors overlapping functional elements at the protein, RNA, and DNA levels. This superimposition of functions leads to complex selective forces acting on all levels of the genome and proteome. Considering the constraints on HIV-1 to maintain such a highly compact genome, we hypothesized that stretches of synonymous conservation would be common within its genome. Results: We used a combined computational-experimental approach to detect and characterize regions exhibiting strong purifying selection against synonymous substitutions along the HIV-1 genome. Our methodology is based on advanced probabilistic evolutionary models that explicitly account for synonymous rate variation among sites and rate dependencies among adjacent sites. These models are combined with a randomization procedure to automatically identify the most statistically significant regions of conserved synonymous sites along the genome. Using this procedure we identified 21 conserved regions. Twelve of these are mapped to regions within overlapping genes, seven correlate with known functional elements, while the functions of the remaining four are yet unknown. Among these four regions, we chose the one that deviates most from synonymous rate homogeneity for in-depth computational and experimental characterization. In our assays aiming to quantify viral fitness in both early and late stages of the replication cycle, no differences were observed between the mutated and the wild type virus following the introduction of synonymous mutations. Conclusions: The contradiction between the inferred purifying selective forces and the lack of effect of these mutations on viral replication may be explained by the fact that the phenotype was measured in single-cycle infection assays in cell culture. Such a system does not account for the complexity of HIV-1 infections in vivo, which involves multiple infection cycles and interaction with the host immune system.
British Columbia Legislative Assembly sessional clipping book (1945-02)
Creators: name: :Unav
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Law
valueUri: http://id.worldcat.org/fast/993678
subject: FOS: Law
subject: Politics and government
valueUri: http://id.worldcat.org/fast/1919741
subject: British Columbia. Legislative Assembly
valueUri: http://id.worldcat.org/fast/600765

description: These Sessional Clippings books cover the period 1891 to 1972, and include newspaper accounts written by various legislative reporters who covered debates occurring in the British Columbia Legislative Assembly. Transcripts of debates of the Legislative Assembly (Hansard) were not published in B.C. until 1970; hence these "Sessional Clipping Books" augment the "Journals", the record of daily proceedings of the Legislative Assembly. Selected clippings from various newspapers including the Vancouver Sun, the Vancouver Province, the Colonist, and the Times newspapers, relating to the newspaper reports concerning activities of the Legislature. The original sessional clippings books comprise 351 ledger size print volumes, held at the Legislative Library in Victoria BC. The print volumes were microfilmed onto 26 reels in 1977 under a Tri University Libraries (TRIUL) project by Precision Micrographic Services (Vancouver, B.C.), with the permission of the Legislative Library, Victoria, British Columbia. This digital collection was created by scanning the 26 microfilm reels.
Teichmüller parameters for multiple BTZ black hole spacetime
Creators: name: Kurita, Yasunari
name: Siino, Masaru
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We investigate the Teichmüller parameters for a Euclidean multiple BTZ black hole spacetime. To induce a complex structure in the asymptotic boundary of such a spacetime, we consider the limit in which two black holes are at a large distance from each other. In this limit, we can approximately determine the period matrix (i.e., the Teichmüller parameters) for the spacetime boundary by using a pinching parameter. The Teichmüller parameters are essential in describing the partition function for the boundary conformal field theory (CFT). We provide an interpretation of the partition function for the genus two extremal boundary CFT proposed by Gaiotto and Yin that it is relevant to double BTZ black hole spacetime.
description: 13 pages, 6 figures
Supernovae with Two Peaks in the Optical Light Curve and the Signature of Progenitors with Low-mass Extended Envelopes
Creators: name: Nakar, Ehud
name: Piro, Anthony L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Early observations of supernova light curves are powerful tools for shedding light on the pre-explosion structures of their progenitors and their mass-loss histories just prior to explosion. Some core-collapse supernovae that are detected during the first days after the explosion prominently show two peaks in the optical bands, including the $R$ and $I$ bands, where the first peak appears to be powered by the cooling of shocked surface material and the second peak is clearly powered by radioactive decay. Such light curves have been explored in detail theoretically for SN 1993J and 2011dh, where it was found that they may be explained by progenitors with extended, low-mass envelopes. Here we generalize these results. We explore, first, whether any double-peaked light curve of this type can be generated by a progenitor with a "standard" density profile, such as a red supergiant or a Wolf-Rayet star. We show that a standard progenitor (1) cannot produce a double-peaked light curve in the $R$ and $I$ bands, and (2) cannot exhibit a fast drop in the bolometric luminosity as is seen after the first peak. We then explore the signature of a progenitor with a compact core surrounded by extended, low-mass material. This may be a hydrostatic low-mass envelope or material ejected just prior to the explosion. We show that it naturally produces both of these features. We use this result to provide simple formulae to estimate (1) the mass of the extended material from the time of the first peak, (2) the extended material radius from the luminosity of the first peak, and (3) an upper limit on the core radius from the luminosity minimum between the two peaks.
description: Revised version uploaded to match version accepted for publication in The Astrophysical Journal, 8 pages, 2 figures
Spontaneous Spatial Inversion Symmetry Breaking and Spin Hall Effect in a Spin-ice Double-exchange Model on a Pyrochlore Lattice
Creators: name: Ishizuka, Hiroaki
name: Motome, Yukitoshi
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: A formation of tetrahedral spin clusters is discovered by Monte Carlo simulation for a spin-ice type double-exchange model on a pyrochlore lattice. The spin-cluster phase is magnetically disordered, but breaks spatial inversion symmetry spontaneously by developing noncoplanar four-spin molecules periodically on the pyrochlore lattice. We find that the system exhibits a nonzero spin Hall conductivity in the spin-cluster phase. The result suggests that an intersite-multipole order induces the unconventional spin Hall state without the spin-orbit interaction.
description: 5 pages, 4 figures, accepted for publication in Rapid Communication section of Phys. Rev. B
Low-dimensional pairing fluctuations and pseudogapped photoemission spectrum in a trapped two-dimensional Fermi gas
Creators: name: Watanabe, Ryota
name: Tsuchiya, Shunji
name: Ohashi, Yoji
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We investigate strong-coupling properties of a trapped two-dimensional normal Fermi gas. Within the framework of a combined $T$-matrix theory with the local density approximation, we calculate the local density of states, as well as the photoemission spectrum, to see how two-dimensional pairing fluctuations affect these single-particle quantities. In the BCS (Bardeen-Cooper-Schrieffer)-BEC (Bose-Einstein condensation) crossover region, we show that the local density of states exhibits a dip structure in the trap center, which is more remarkable than the three-dimensional case. This pseudogap phenomenon is found to naturally lead to a double peak structure in the photoemission spectrum. The peak-to-peak energy of the spectrum at p=0 agrees well with the recent experiment on a two-dimensional 40K Fermi gas [M. Feld, et al., Nature 480, 75 (2011)]. Since pairing fluctuations are sensitive to the dimensionality of a system, our results would be useful for the study of many-body physics in the BCS-BEC crossover regime of a two-dimensional Fermi gas.
description: 20 pages, 7figures, Phys. Rev. A (2013), in press
title: Rarvm Mvtvi Amoris Et Amicitiæ Exemplum; [1724]
title: Selzammes Beyspiel Wunderwürdiger Freundschafft Und Gegen-Lieb Zwischen zweyen Königlichen Printzen, Auff offentlicher Schau-Bühne vorgestellt Von dem Churfürstlichen Gymnasio der Societät Jesu Zu Landshut. Den 4. und 5. Tag Herbstmonaths in dem Jahr 1724.
titleType: Subtitle
Creators: name: Ulrich, Maximilian
name: Michel, Andreas
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2014

description: Komponist auf Seite [8] genannt: "Musicam composuit ... Dom. Maximilianus Ulrich, Cantor ad SS. Martini & Castuli, &c."
Bathyergidae Waterhouse 1841
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Bathyergidae

description: Family Bathyergidae REVIEWED BY: H. Levenson (HL). ISIS NUMBER: 5301410032000000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 592, DOI: 10.5281/zenodo.7353039
Additional file 1 of Development and internal validation of a predictive risk model for anxiety after completion of treatment for early stage breast cancer
Creators: name: Harris, Jenny
name: Purssell, Edward
name: Cornelius, Victoria
name: Ream, Emma
name: Jones, Anne
name: Armes, Jo
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Supplement 1. Summary of final imputation model specification. Supplement 2. Illustration of the LASSO estimates. Supplement 3. Estimates for model selection using univariate screening.
Additional file 1 of Pilot implementation of a home-care programme with chlamydia, gonorrhoea, hepatitis B, and syphilis self-sampling in HIV-positive men who have sex with men
Creators: name: J. Leenen
name: C. J. P. A. Hoebe
name: R. P. Ackens
name: D. Posthouwer
name: I. H. M. Van Loo
name: P. F. G. Wolffs
name: Dukers-Muijrers*, N. H. T. M.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Appendix 1. Online questionnaire for MSM using home sampling kit (English version).
Additional file 1 of Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system
Creators: name: Wafai, Razan
name: Williams, Elizabeth D.
name: Souza, Emma De
name: Simpson, Peter T.
name: Reed, Amy E. McCart
name: Kutasovic, Jamie R.
name: Waltham, Mark
name: Snell, Cameron E.
name: Blick, Tony
name: Thompson, Erik W.
name: Hugo, Honor J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 1: Supplementary Fig. 1. Stromal area in EDW01 tumour cores across serial passaging in mice does not increase. Connective tissue visualised by the Masson’s Trichrome stain, × 4 magnification, scale bar = 200 μM.
title: Unschuld Gedruckt, doch nicht Unterdruckt In Triumphierender Marter, und glorreichen Todt Deß Heiligen Joannis von Nepomuck, Mächtigisten Schutz-Patron deß Königreichs Böhmen, und gantzen Teutschlands: auch sonderbahrer Beschützer der Ehr, und Abwender deß öffentlichen Spotts; 1732
title: Aufgeführt: Auf offentlicher Schau-Bühne in dem Rath-Hauß der Churfürstlichen Stadt Mospurg, Von Einigen zu der Ehre und Andacht sonders geneigten Burgerschafft allda. Den ... und ... Monats-Tag
titleType: Subtitle
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2014

description: Perioche
Key factors leading to reduced recruitment and retention of health professionals in remote areas of Ghana: a qualitative study and proposed policy solutions
Creators: name: Snow, Rachel
name: Asabir, Kwesi
name: Mutumba, Massy
name: Koomson, Elizabeth
name: Gyan, Kofi
name: Dzodzomenyo, Mawuli
name: Kruk, Margaret E.
name: Kwansah, Janet
Publisher: name: Columbia University
Year: 2011
Subjects: Medical care
Medical sciences
Africans

description: Background: The ability of many countries to achieve national health goals such as the Millennium Development Goals remains hindered by inadequate and poorly distributed health personnel, including doctors. The distribution of doctors in Ghana is highly skewed, with a majority serving in two major metropolitan areas (Accra and Kumasi), and inadequate numbers in remote and rural districts. Recent policies increasing health worker salaries have reduced migration of doctors out of Ghana, but made little difference to distribution within the country. This qualitative study was undertaken to understand how practicing doctors and medical leaders in Ghana describe the key factors reducing recruitment and retention of health professionals into remote areas, and to document their proposed policy solutions. Methods: In-depth interviews were carried out with 84 doctors and medical leaders, including 17 regional medical directors and deputy directors from across Ghana, and 67 doctors currently practicing in 3 regions (Greater Accra, Brong Ahafo, and Upper West); these 3 regions were chosen to represent progressively more remote distances from the capital of Accra. Results and discussion: All participants felt that rural postings must have special career or monetary incentives given the loss of locum (i.e. moonlighting income), the higher workload, and professional isolation of remote assignments. Career 'death' and prolonged rural appointments were a common fear, and proposed policy solutions focused considerably on career incentives, such as guaranteed promotion or a study opportunity after some fixed term of service in a remote or hardship area. There was considerable stress placed on the need for rural doctors to have periodic contact with mentors through rural rotation of specialists, or remote learning centers, and reliable terms of appointment with fixed end-points. Also raised, but given less emphasis, were concerns about the adequacy of clinical equipment in remote facilities, and remote accommodations. Conclusions: In-depth discussions with doctors suggest that while salary is important, it is career development priorities that are keeping doctors in urban centers. Short-term service in rural areas would be more appealing if it were linked to special mentoring and/or training, and led to career advancement.
A Deuring criterion for abelian varieties
Creators: name: Blake, Chris
Publisher: name: arXiv
Year: 2013
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11G10, 11G15

description: We give several generalisations of the Deuring reduction criterion for elliptic curves to abelian varieties of higher dimension. In particular the Newton polygon of the reduction of an abelian variety A with complex multiplication by F at a prime above p can be explicitly computed in terms of the CM type of A and the decomposition group of a suitable prime above p in a Galois closure of F. Conversely, it is shown that the formal isogeny type of the reduction of A at a prime above p places certain restrictions on the decomposition of p in F.
description: 7 pages
Additional file 4 of Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system
Creators: name: Wafai, Razan
name: Williams, Elizabeth D.
name: Souza, Emma De
name: Simpson, Peter T.
name: Reed, Amy E. McCart
name: Kutasovic, Jamie R.
name: Waltham, Mark
name: Snell, Cameron E.
name: Blick, Tony
name: Thompson, Erik W.
name: Hugo, Honor J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 4: Supplementary Fig. 4. A Representative images of CD44 and Masson’s Trichrome for the the ED03 and EDW01 PDXs at the indicated passage numbers. The numbers of xenografts examined at various passage numbers are as follows: for ED03 – p3: 6; p5: 5; p7: 7; for EDW01 – p3: 8; p5: 8; p7: 3. Magnification 4x, scale bar = 200 μM. B. CD44/24 images shown in Fig. 3, split into their respective colours to illustrate staining. Magnification 10x, scale bar = 100 μM.