cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Heparinized segmented polyurethaneurea surfaces with hydrophilic spacer groups.
Creators: name: Park, Ki Dong
Publisher: name: University of Utah
Year: 2012
Subjects: Pharmacology
Biomedical Polymers

description: A new heparin-immobilized segmented polyurethaneurea (SPUU, Biomer®) surface using hydrophilic PEO chain as a spacer was developed for surface modification by two different methods. The first method involved the in situ surface immobilization of heparin onto SPUU surface, and the other method utilized the coating of a newly synthesized SPUU-PEO-Heparin graft copolymer.  The in situ surface immobilization procedure involved the coupling of telechelic diisocyanate-derivatized PEO spacer to SPUU through allophanate and biuret reactions. The reactions leave a free isocyanate on the spacer group which was then coupled through a condensation reaction to functional groups (-OH, NHb2) on heparin.  In situ heparin-immobilized SPUU surfaces were evaluated in vitro, ex vivo, and in vivo to investigate the efficacy of heparin immobilization using long PEO spacers and the effect of spacer length on their biological response with blood. The heparin-immobilized surface demonstrated a much improved blood compatibility when compared to SPUU and PEO grafted SPUU (without heparin). The surface with long spacer groups had increased in vitro heparin activity and minimized platelet adhesion and activation. This correlated well with the improved blood compatibility in ex vivo rabbit shunts and in vivo canine long term implants. Improved blood compatibility was attributed to the prevention of fibrin net formation by immobilized heparin, resulting in a reduction of fibrin induced platelet aggregation and subsequent thrombus formation. However, the PEO grafted surface without heparin failed to prevent thrombus formation in whole blood, although it reduced in vitro platelet adhesion and activation.  A new SPUU-PEO-Heparin graft copolymer was synthesized by a similar synthetic procedure as used for in situ surface immobilization and characterized to investigate the interaction between the blood and copolymer surface. Biological responses with blood in in vitro and ex vivo were comparable to an in situ surface immobilized system and attest to the usefulness of this new procedure as a coating to improve the blood compatibility of blood contacting surface.
Sonnenfleckenzeichnung Nr. 21114.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.07.1962, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.08.1962, erstellt von B. Jamnicky am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
#2032782 Elements: Models and tools for on-line design and simulations for DNA and RNA nanotechnology
Creators: name: Sulc, Petr
name: Stephanopoulos, Nicholas
name: Yan, Hao
Publisher: name: Zenodo
Year: 2022

description: Poster describing results of NSF-funded project #2032782 Elements: Models and tools for on-line design and simulations for DNA and RNA nanotechnology
description: Grant: NSF #2032782: Elements: Models and tools for on-line design and simulations for DNA and RNA nanotechnology
Sonnenfleckenzeichnung Nr. 21240.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.11.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.10.1962, erstellt von Baltog, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Puri Cardoso-Costa, Azevedo & Ferreira 2013
Creators: name: Martins, Caleb C.
name: Ardila-Camacho, Adrian
name: Rivera-Gasperín, Sara Lariza
name: Oswald, John D.
name: Liu, Xingyue
name: Contreras-Ramos, Atilano
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Megaloptera
Corydalidae
Puri

description: Genus Puri Cardoso-Costa, Azevêdo & Ferreira, 2013
Puri Cardoso-Costa, Azevêdo & Ferreira, 2013: 392. Type species. Puri aleca Cardoso-Costa, Azevêdo & Ferreira, 2013: 392 (by original designation).
Included species
Puri aleca Cardoso-Costa, Azevêdo & Ferreira, 2013
Neotropical (Brazil).
description: Published as part of Martins, Caleb C., Ardila-Camacho, Adrian, Rivera-Gasperín, Sara Lariza, Oswald, John D., Liu, Xingyue & Contreras-Ramos, Atilano, 2022, A world checklist of extant and extinct species of Megaloptera (Insecta: Neuropterida), pp. 1-93 in European Journal of Taxonomy 812 (1) on page 46, DOI: 10.5852/ejt.2022.812.1727, http://zenodo.org/record/6448732
Comparative studies of cellular resistance to Candida albicans infections in mice
Creators: name: Hadfield, Ted L.
Publisher: name: University of Utah
Year: 2012
Subjects: Endotoxins
Antibiotics

description: The quantitative extent of resistance induced by specific and nonspecific immunization to systemically induced C. albicans infection was investigated in mice.  Animals were specifically immunized by i.p. injections of formalinized suspension of C. albicans.  Nonspecific resistance was induced by temporally spaced subcutaneous injections of endotoxin.  The mice were hallenged by i.v. injections of known numbers of C. albicans.  Animals were sacrificed at 24 hours intervals; cultures of spleen, liver, and kidney for viable C. albicans were done on antibiotic blood agar.  In vitro studies were evaluated by comparing kinetic curves of inactinations of c. albicans by macrophages from various systems, that is, from animals that wer immunized, endotoxin treated or treated with saline.  Lymphocytes plus macarophasges from the various systems were also challenged to determine if the lymphocyte was functionally involved with the destruction of C. albicans.  The most significant in vivo result was that fewer yeast were found in the kidneys of immunized animals.  The kidneys of the endotoxin treated animasl and the saline treated animals were heavily infected.  No significant differences were observed in the livers and spleens of the different groups throughout the experiement. In vitro results indicate that macarophages from immunized animals have slightly but sutatistically significant enhance cytopeptic capacities when compared to macrophages from endotoxin treated and saline treated animals.  Lylmphocytes appeard to enhace the cytopeptic response after a temporal delay which was not observed in cultures containin gonoy macrophages.  The data suggest that macrophages from immunized animals, endotoxin treated animals or saline treated animals yieled a steeper inactivation curve.  Reflecting death of the challenge organism, than the systems containing lymphocytes form the various systems acting in conjunction with macrophages from a homologous or heterologous system.  Lylmphocytes from immunized animals and lymphocytes from endotoxin treated animals did enhance the cytopeptic capacities of macrophages from saline treated animals when comparisons to the lymphocyte-macrophage saline control system were made.  This enhanced cytopepsis that occurred n the presence of the lymphocyte was not as pronounced n systems containing lymphocytes and macrophages form immunized animals and/or endotoxin treated animals.  The fact that endotoxin treated lymphocytes stimulate the cytopeptic capacities of saline treated macrophages indicates a mechanism for the induction of nonspecific resistance.  This implies that the mechanism of nonspecific resistance included cellular components and that both the lymphocyte and macrophage participate.
Influence of cannabidiol and delta 9-tetrahydrocannabinol on cobalt epilepsy in rats
Creators: name: Chiu, Pauline
Publisher: name: University of Utah
Year: 2012
Subjects: Tetrahydrocannabinol

description: The mechanisms of the anticonvulsant activity of cannabidiol  (CBD) and the central excitation of  delta9- -tetrahydrocannabinol (Delta9 -THC) were investigated electrophysiologically with conscious, unrestrained cobalt epileptic rats.   The well-known antiepileptics, trimethadione, ethosuximide and phenytoln, were included as reference drugs.   Direct measurements were made of spontaneously firing, epileptic potentials from a primary focus on the parietal cortex and convulsions were monitored visually.   Ethosuximide and trimethadione decreased the frequency of focal potentials, but phenytoin and CBD exerted no such effect.   Although CBD did not suppress the focal abnormality, it abolished jaw and limb clonus.  Consequently, CBD may produce its anticonvulsant effect by depressing seizure spread in the CNS.   In contrast, delta9-THC markedly increased the frequency of focal potentials, evoked generalized bursts of polyspikes and produced frank convulsions, 11-OH-delta9 -THC, the major metabolite of delta -THC displayed only one of the excitatory properties of the parent compound:   production of bursts of poiyspikes.   In contrast to delta-THC and its 11-OH-metabolite, CBD, even in very high doses, did not induce any excitatory effects or convulsions.   The present study provides the first evidence that CBD exerts anticonvulsant activity against the motor manifestations of a  focal epilepsy, and that the mechanism of the effect may involve a depression of seizure spread in the CNS.
Sonnenfleckenzeichnung Nr. 21097.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.06.1962, erstellt von Helmut Müller und Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 21144.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.08.1962, erstellt von Werner Scheidegger.
Zusätzlich ist vermerkt: Sonnenturm
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.06.1962, erstellt von Alexandra Parepeanu, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Lightning Talk: HyLoC: Objective-driven Adaptive Hybrid Lossy Compression Framework for Extreme-Scale Scientific Applications
Creators: name: Tao, Dingwen
name: Di, Sheng
Publisher: name: Zenodo
Year: 2022
Subjects: Lossy compression
Cyberinfrastructure
HPC
I/O

description: This slide is to introduce the NSF CSSI project - HyLoC, which aims to develop a hybrid lossy compression framework to automatically construct the best-fit compression for diverse user objectives in data-intensive scientific research.
description: NSF CDS&E Awards #2042084 and #2003709
Sonnenfleckenzeichnung Nr. 21099.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.06.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Decision tree classification of dambo wetlands using remotely sensed multispectral and topographic data
Creators: name: Hansen, Matthew Kade
Publisher: name: University of Utah
Year: 2012
Subjects: Vegetation mapping,Uganda
Wetland ecology, Uganda
Methane,Environmental aspects, Uganda
Remote sensing,Uganda

description: Wetlands are the greatest single source of atmospheric methane (CH4), an important greenhouse gas. While the CH4 emissions from the expansive dambo wetlands of tropical Africa are likely substantial, they have not been reliably measured or estimated. Vegetation, topography, and soils vary among the following dambo land  system zones: uplands, margins, floors, and bottoms. CH4 production also presumably  varies among these zones, with the greatest emissions most likely originating from the  bottoms. Multispectral and topographic remote sensing data were used to create a 20 m  resolution classified map of dambo land system zones within a 2,214 sq km study area  located in central Uganda. Training and accuracy assessment ground truth data were  collected during a 4-week field campaign in the Ugandan study area. Multispectral inputs included reflectance values, vegetation indices, and spectral mixture modeling fractions from SPOT 4 satellite images acquired December, 2006, and February, 2007.  Topographic inputs consisted of a digital elevation model (DEM), slope, and 20 relative  elevation layers calculated using moving windows of various sizes. A binary decision  tree (BDT) was used to create decision rules for the study area classification. Decision  rules were based upon the following input variables: the Normalized Difference  Vegetation Index (NDVI); the Normalized Difference Infrared Index (NDII); the  shortwave infrared (SWIR) image band; northing value, in terms of Universal Transverse Mercator (UTM) projected coordinates; slope; and two relative elevation layers. The overall classification accuracy of 75.5% and Kappa (K) coefficient of 0.67.
Sonnenfleckenzeichnung Nr. 21145.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.08.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.01.1966, erstellt von Sabahat Bengi an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung Nr. 21221.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.11.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Investigating colon tumor cell response to 5-Aza-2'-deoxycytidine:  analysis of the CDX2 promoter and its methylation status .
Creators: name: Moore, Brent Christopher
Publisher: name: University of Utah
Year: 2012
Subjects: DNA
CDX Genesl

description: Cytosine methylation silences gene activation and is indicative of an inactive chromatin state.  This is especially true in tumors when tumor suppressor genes are silenced by methylation.  Because methylation silencing is reversible, DNA methylation has been identified as a potential drug target.  Methylation-inhibiting drugs such as 5-AZa-2'-deoxycytidine (5-Aza-CdR) have been shown to reverse methylation and induce differentiation in cell culture, and these drugs are now under investigation in numerous clinical trails.  Most clinical investigations of 5-Aza-CdR have focused on malignant hematologic disease, and few clinical trials have been performed in solid tumors.  Given the number of methylation-silenced tumor suppressor genes in solid tumors a better understanding the mechanisms and targets of hypomethylating agents is needed.  The goal of this dissertation is to better define the cellular responses of colon cancer cells to 5-Aza-CdR.  Our findings provide new insights about the effects of hypomethylation by 5-Aza-CdR in colorectal adenocarcinoma.  I found the p53 DNA damage response pathway is activated in colorectal tumor cells after 5-Aza-CdR treatment, and that cells that express wild-type p53 are more sensitive to 5-Aza-CdR mediated growth arrest and toxicity. CDX2 expression is greatly reduced in the later stages of human colorectal carcinogenesis and in some human colorectal cancer-derived cell lines.  I found that the CDX2 gene is re-expressed in colon tumor cells treatment with 5-Aza-CdR, and that there is a region of the CDX2 promoter that is selectively methylated in tumor cells that lack CDX2 expression and in normal cells of non-epithelial origin.  These results indicate the methylation plays a role in regulating CDX2 expression in both normal and neoplastic tissues and suggests that cytosine methylation is important in the establishment and maintenance of tissue-specific gene expression. Building on my observation about 5-Aza-CdR and CDX2, I tested the role of CDX2 activation in the restoration of RA responsiveness in colon tumor sells, and found the CDX2 alone is not sufficient.  Lastly, I identified an intergenic region upstream of CDX2 that is transcribed in a manner that correlates with CDX2 expression.  These preliminary results in this area help to explain why an isolated intergenic region should be the target of methylation in tumor cells.
Sonnenfleckenzeichnung Nr. 21155.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.08.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Context-Dependent Modulation of the Tumor Suppressor Programed Cell Death 4 (PDCD4) by Argenine Methylation
Creators: name: Fay, Marta Marie
Publisher: name: University of Utah
Year: 2014

description: Programmed cell death 4 (PDCD4) is a well-characterized tumor suppressor whose loss correlates with poor patient prognosis in many cancers. Yet some patients whose tumors express PDCD4 still have poor prognosis. In this dissertation, I report the identification of protein arginine methyltransferase 5 (PRMT5) as a new PDCD4 binding partner that when coexpressed with PDCD4 in a xenograft model of breast cancer causes accelerated tumor growth, dependent on both catalytically active PRMT5 and methylcompetent PDCD4. Furthermore, analysis of two independent breast cancer data sets indicates that expression of high PDCD4 and low PRMT5 correlates with better patient outcome while expression of high PDCD4 and high PRMT5 associates with poor outcome. Together, these data suggest that arginine methylation of PDCD4 switches its function from a tumor suppressor to an oncogene. This oncogenic interaction is primarily dictated by the target residue arginine 110 and secondarily by adjacent basic residues that further enhance the binding interaction. Additionally, the interaction is sensitive to levels of the universal methyl donor, Sadenosyl- L-methionine (SAM). SAM levels were found to be increased in a panel of breast cancer cells compared to a noncancerous cells line, suggesting that SAM levels are a variable to consider with regard to the PDCD4-PRMT5 interaction. iv Additionally, I report that PDCD4 is methylated during nutrient deprivation due to stabilization of PDCD4 levels and increased activity of PRMT5. Moreover, methylation of PDCD4 promotes a higher affinity interaction with the RNA helicase eIF4A and increases cell viability during nutrient deprivation. Due to poorly formed vasculature, solid tumors often have nutrient-deprived regions where methylation of PDCD4 could occur to sustain viability of cells coexpressing PDCD4 and PRMT5. These data further support that the role of PDCD4 in cancer biology should be considered in a context-dependent manner.
Lymphocyte sister chromatid exchange frequency in coke oven workers.
Creators: name: Miner, Joseph Kay
Publisher: name: University of Utah
Year: 2012
Subjects: Chromosome Analysis
Hydrocarbons

description: Lymphocyte sister chromatid exchange (SCE) frequencies were determined for 12 long-term exposed male coke-oven workers as well as for 12 other age-matched steelworkers with no coke oven work exposure.  Both groups were non-smokers and had mean ages of 54.7 and 54.9 years, respectively.  The exposed group had a mean of 28.9 years continuous work exposure to the coke oven emissions.  SCE frequencies for the exposed individuals ranged from 7.97 to 11.20 SCEâ€™s/cell while the control individual ranged from 6.73 to 10.60 SCEâ€™s/cell.  The mean SCE frequency for the exposed group was 9.54 Â± S.D. 1.15 SCEâ€™s/cell, and was 14% higher than the 8.35 Â± S.D. 1.09 SCEâ€™s/cell of the control group (p=.016).  The long-term exposure to coke oven emissions experienced by the coke oven workers may be the explanation for this difference.
Sonnenfleckenzeichnung Nr. 21106.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.06.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Lightning Talk: ROCCI: Integrated Cyberinfrastructure for In Situ Lossy Compression Optimization Based on Post Hoc Analysis Requirements
Creators: name: Di, Sheng
name: Cappello, Franck
name: Tao, Dingwen
Publisher: name: Zenodo
Year: 2022
Subjects: HPC
Cyberinfrastructure
Lossy compression
HDF5
Post hoc analysis

description: This slide is to introduce the NSF CSSI project - ROCCI, which aims to develop a Requirement-Oriented Compression Cyber-Infrastructure (ROCCI) for data-intensive domains such as astrophysics and materials science.
description: NSF CSSI Awards #2104023 and #2104024
Development Of Detection Methods For Viruses On Potato (Pvt, Apmov, Aplv And Apmmv) And Test Performance Study
Creators: name: Monger, Wendy
Publisher: name: Zenodo
Year: 2018
Subjects: Euphresco, potato, viruses, diagnostics, NGS, RT-PCR

description: Slide of the Euphresco project 2016-A-207 'Development of detection methods for viruses on potato (PVT, APMoV, APLV and APMMV) and test performance study'
description: Project funded through the Euphresco network
Sonnenfleckenzeichnung Nr. 21150.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.08.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.09.1962, erstellt von Adnan Kiral an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Portable terminal for data input in a coronary care unit.
Creators: name: Miller, Gregory Alan
Publisher: name: University of Utah
Year: 2012
Subjects: Hardware Design
Patients

description: A new manual describes a data acquisition system for that is used in a Coronary Care Unit environment (CCU) This system is designed to provide a data entry mechanism of sufficient ease that the nursing staff of the CCU will enter clinical data required to supplement a medical decision making system (HELP) in use at the LDS Hospital.  State of the art microprocessor technology was used in development of small portable bedside terminals (PBT's) to preprocess input data and provide an interfacing capability to a central computer facility.  The project was designed in two parts:  (1) Development of software required to translate coded input data to a dictionary defined coded data structure for storage in a patient medical data file; (2) concurrent construction and testing of portable bedside terminals and bedside display devices.  Through testing and acceptance of this system still awaits use by the CCU nursing staff.  The portable terminal, display device and the decoding/message translator software have been tested in a laboratory setting using actual CCU patient data.  Additionally, a successful simulation of the new data collection schema has been performed in the CCU environment using an existing computer terminal (at the nurse's station.)  It was found that the PBT system will capture all the data currently manually input by computer technicians.  The PBT system will provide a new bedside interface for physician, nurse and patient with the medial database.  Increased accuracy and timeliness of patient data captured from the "real time" manual data entry will improve the ability of a computer based decision-making system to provide assistance to physicians and nurses.
Cratocorydalopsis Jepson & Heads 2016
Creators: name: Martins, Caleb C.
name: Ardila-Camacho, Adrian
name: Rivera-Gasperín, Sara Lariza
name: Oswald, John D.
name: Liu, Xingyue
name: Contreras-Ramos, Atilano
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Megaloptera
Corydalidae
Cratocorydalopsis

description: Genus † Cratocorydalopsis Jepson & Heads, 2016
† Cratocorydalopsis Jepson & Heads, 2016: 136. Type species. † Cratocorydalopsis brasiliensis Jepson & Heads, 2016: 136 (by original designation).
Taxonomic notes
† Cratocorydalopsis is a monotypic and extinct genus only known by one species, † Cratocorydalopsis brasiliensis, from the Early Cretaceous Crato Formation of Brazil. This genus was placed in Corydalidae by Jepson & Heads (2016) based on the structure of the fourth tarsomere (simple) and general wing venation pattern; nevertheless, the subfamily placement of † Cratocorydalopsis is difficult to determine due to the preservation of the fossil, which makes observation of the necessary characters to identify the subfamily difficult.
Included species
† Cratocorydalopsis brasiliensis Jepson & Heads, 2016
Neotropical (Brazil) [Early Cretaceous].
description: Published as part of Martins, Caleb C., Ardila-Camacho, Adrian, Rivera-Gasperín, Sara Lariza, Oswald, John D., Liu, Xingyue & Contreras-Ramos, Atilano, 2022, A world checklist of extant and extinct species of Megaloptera (Insecta: Neuropterida), pp. 1-93 in European Journal of Taxonomy 812 (1) on page 48, DOI: 10.5852/ejt.2022.812.1727, http://zenodo.org/record/6448732
Sonnenfleckenzeichnung Nr. 21101.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.06.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Additional file 1 of Working toward improved monitoring of Cryptosporidium and Giardia (oo)cysts in water samples: testing alternatives to elution and immunomagnetic separation from USEPA Method 1623.1
Creators: name: Fradette, Marie-Stéphanie
name: Charette, Steve J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1:. Figure S1. Photograph of the EnviroChek HV filtration cartridge following opening with a pipecutter during the alternative elution protocol. Figure S2. Picture of bacteria carried over by the immunomagnetic separation. Figure S3.. Comparison of a Cryptosporidium oocyst (A) with beads from the IMS beads (B).Table S1. Detailed evaluation of the costs associated with the techniques presented in this article.
Tissue pharmacokinetics for prevention of hemodialysis vascular access stenosis.
Creators: name: Goteti, Kosalaram
Publisher: name: University of Utah
Year: 2012
Subjects: Pharmacogenetics
Grafts

description: The amphetamine-like compounds have prominent effects on several neurotransmitter systems within the central nervous system. The administration of multiple doses of these stimulants produces profound and long-lasting decreases in neurochemical indices of dopamine and serotonergic systems as well as increases in the concentration of the neuropeptide, substance P, within various brain regions. The nonselective dopamine receptor antagonist, haloperidol, blocks these effects of methamphetamine on all three neurotransmitter systems. The purpose of the present investigations was to identify the dopamine receptor subtype(s) which mediate these actions of methamphetamine. Thus, selective D1 and D2 agonists and antagonists were administered alone or in combination with methamphetamine and the effects of these treatments on neurochemical parameters of the dopamine, serotonin, and substance P systems were evaluated. The results from these present studies suggest that methamphetamine-released dopamine actions on the D2 receptor mediate the effects of methamphetamine on the nigrostriatal dopamine and striatonigral substance P systems. In contrast, the effects of methamphetamine on serotonin systems appear to involve dopamine actions on the D1 receptor. A single administration of an amphetamine produces a rapid, but transient depression of serotonin synthesis. The coadministration of dopamine antagonists with methamphetamine did not modify the methamphetamine effect on tryptophan hydroxylase activity, the rate-limiting enzyme in serotonin synthesis. These findings suggest a different mechanism is involved in this acute, transient effect of methamphetamine versus the long-lasting effects observed after multiple administrations. Whereas D1 blockade attenuates the effects of methamphetamine on the serotonergic system in the multiple dosing paradigm, it does not afford protection against the acute effect.
Sonnenfleckenzeichnung Nr. 21234.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.11.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Fetal heart rate as a predictor of sex.
Creators: name: Nash, Teresa Burt
Publisher: name: University of Utah
Year: 2012
Subjects: Satistical Analysis

description: The purpose of this descriptive study was to determine the relationship between the fetal heart rate during the last trimester of pregnancy and the sex of the baby.  The fetal heart rates of 51 subjects were auscultated and counted between 32 and 42 weeks of gestation with the use of ultrasound monitors.  The mean heart rate for 23 males was 137.8 beats per minute (BPM) and for 28 females was 138.2 BPM.  There was no significant difference found between the two groups.  There was also no significant difference shown in individual fetal heart rates as the fetus matured from 34 to 38 weeks gestation.  On the basis of these findings and a review of the literature, it was concluded that the  fetal heart rate cannot be used as an accurate method for predicting the sex of the baby.
Sonnenfleckenzeichnung Nr. 21140.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.08.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Comparison of middle component potentials of preterm infants with preterm infants who had intraventricular hemorrhage.
Creators: name: Young, Beverly A
Publisher: name: University of Utah
Year: 2012
Subjects: Hemorhage
Audoitory

description: Fifteen preterm infants in the Newborn Intensive Care Unit, University of Utah Medical Center, were studied in an attempt to describe the middle component response (8-50 msec post-stimulus) of the auditory evoked potentials.  Five of the preterm infants had intraventricular hemorrhage (IVH) without severe birth asphyxia.  Their middle component response was compared with the middle component response of ten preterm infants who did not have IVH or severe birth asphyxia (Group II).  The middle component responses of these two groups were elicited by both click and tone stimuli.  Both groups were tested after 34 weeks of age by birth dates while they were observed as being asleep.  The middle component responses, peaks Po, Na, Pa, and NB, were described according to mean, range, and standard deviation.  There was no significant statistical difference between the middle component response of the preterm infant with IVH compared with the preterm infant without IVH using paired t-test analysis.  It was aw subjective finding of the study that the tone pip stimuli elicited a â€œclearerâ€ response than did the click stimuli.  The investigator concluded that there was no significant statistical difference between the middle component response of preterm infants with IVH and preterm infants without IVH.  It is recommended by the investigator that a larger sample be obtained to study the middle component response more extensively in preterm infants.
Lithocorydalus Jepson & Heads 2016
Creators: name: Martins, Caleb C.
name: Ardila-Camacho, Adrian
name: Rivera-Gasperín, Sara Lariza
name: Oswald, John D.
name: Liu, Xingyue
name: Contreras-Ramos, Atilano
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Megaloptera
Corydalidae
Lithocorydalus

description: Genus † Lithocorydalus Jepson & Heads, 2016
† Lithocorydalus Jepson & Heads, 2016: 139. Type species. † Lithocorydalus fuscata Jepson & Heads, 2016: 139 (by original designation).
Taxonomic notes
† Lithocorydalus is an extinct genus known only from one Early Cretaceous species, † Lithocorydalus fuscata, from the Brazilian Crato Formation. Jepson & Heads (2016) described this genus as belonging to Corydalidae and, similar to † Cratocorydalopsis, its subfamily placement is doubtful due to the preservation of the fossil.
Included species
† Lithocorydalus fuscata Jepson & Heads, 2016
Neotropical (Brazil) [Early Cretaceous].
description: Published as part of Martins, Caleb C., Ardila-Camacho, Adrian, Rivera-Gasperín, Sara Lariza, Oswald, John D., Liu, Xingyue & Contreras-Ramos, Atilano, 2022, A world checklist of extant and extinct species of Megaloptera (Insecta: Neuropterida), pp. 1-93 in European Journal of Taxonomy 812 (1) on page 48, DOI: 10.5852/ejt.2022.812.1727, http://zenodo.org/record/6448732
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.08.1962, erstellt von Emilia Tifrea, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Characterization of the NF1 gene and its gene product, neurofibromin.
Creators: name: Xu, Gangfeng Cloning
Publisher: name: University of Utah
Year: 2012
Subjects: cDNA
Genes

description: The neurofibromatosis 1 gene (NFl) spans approximately 350 kb of genomic DNA. To develop a comprehensive screen for NFl mutations, I constructed a genomic DNA contig that included the entire NFl cDNA sequence. Using these genomic clones, I identified all intron-exon boundaries of the NFl coding region and established that the gene comprises 59 exons. The flanking intronic sequences obtained enabled me and others to design intron-based oligonucleotide primers to amplify NFl exons.  I also discovered a locus homologous to NFl on chromosome 15. In spite of its high degree of sequence homology with NF1, frame-shifting deletions in some exons of the chromosome 15 locus destroy the intact coding  sequence.  NFl encodes a p21ras GTPase-activating protein (GAP). Since p21ras-GTP is a major regulator of cellular proliferation, mutant neurofibromins with diminished GAP activity might deregulate the ras-GTP level and contribute to the development of tumors. With this hypothesis in mind, I found an amino acid substitution (altering Lys-1423, in the NFl GAP-related-domain [NF1-GRD]) in three tumor samples: a colorectal adenocarcinoma, bone marrow from a myelodysplastic syndrome patient, and an anaplastic astrocytoma. I further proved that this substitution causes a drastic decrease in GAP activity.  Since I also found somatic mutations in NFl   in some breast cancer samples, I constructed several NF1 -deficient breast epithelial cell lines using an antisense-cDNA method. However, I have found no evidence that these cells  are tumorigenic.  To further explore the tumor-suppressive role of NF1, I overexpressed full-length NF 1 cDNA, as well as wild type and mutant (K1423E) NF1-GRD, in a colon carcinoma cell line, and demonstrated that overexpression of all three constructs suppressed the tumor phenotype. I also demonstrated that Raf-1 kinase (a downstream effector of p21ras) activity was reduced in cells with overexpressed neurofibromin and that reintroducing an activated Raf-1 kinase domain can reverse tumor suppression. I therefore concluded that tumor suppression by neurofibromin is not due to GAP activity, but rather to tight binding to p21ras-GTP.
Sonnenfleckenzeichnung Nr. 21134.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.07.1962, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Strangers in the courtroom: an examination of access theory and the public's right to open courts from Depasquale to Richmond
Creators: name: Fattah, Geoffrey
Publisher: name: University of Utah
Year: 2012
Subjects: Access
Courts
Depasquale
Journalism
Richmond
Right to know

description: The First Amendment to the U.S. Constitution mentions no citizen right to access government information. However, a series of U.S. Supreme Court decisions forged an implied right to access information through the First Amendment. This approach to finding new constitutional rights within the language and spirit of the Constitution shows how our fundamental rights are ever-growing and evolving to adapt to modern needs. The origins of this movement can be traced back to legal and free speech philosophers who insisted that for a democracy to function, its citizenry must be well informed. This thesis is an historic and legal analysis of the Supreme Court's finding of a right of access through Richmond Newspapers v. Virginia, and the one-year period before the ruling in which the Gannett Newspapers v. DePasquale decision caused hundreds of motions for court closures.  In 1980, justices established the press and public have a constitutional right to attend court hearings. However, courts across the nation continue to resist attempts by the public and press to attend hearings, giving little weight to their right of access. Although the U.S. Supreme Court has established that an overriding government interest must be shown to close a court hearing, many judges fail to take the right of access seriously and have chosen to accept flimsy government requests for closure. Given fractured opinions by the justices in Richmond this thesis has identified a need for a clear legal test to judge a right of access. This includes making court access an affirmative right, showing substantial probability of prejudicial harm for closure, considering alternatives to closure, including the right of the public to object and be heard, ensuring the narrow tailoring of any closure order, and limiting the time span of any closure order so the public can access hearing transcripts.  Applying a clear legal test will support the constitutional rights of the public and press to access government information and give clear guidance to judges on how to handle requests for court closure. Clarifying the confusion created by multiple opinions regarding access will maintain transparency of justice and confidence in our courts.
Sonnenfleckenzeichnung Nr. 21149.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.08.1962, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt