cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Making Reading In A Second Language More Enjoyable
Creators: name: Oosterhof, Jorrit
name: Digkas, Georgios
name: Lungu, Mircea
Publisher: name: Zenodo
Year: 2016
Subjects: second language acquisition
human computer interaction
applied linguistics

description: When learning a second language, one usually follows a learning program, which includes studying lists of words, reading standard texts and doing exercises. Learning a second language is much more enjoyable if one enjoys reading materials in the new language. Articles that are not too long, written about topics the student likes could be a good way to keep the reader motivated in reading more and thus learning the language.

However, if the student does not know what a word means he has to look it up in a dictionary, and this means losing time, time that could have been better spent reading some more second language materials. One of the hypotheses of this work is that it might be more productive if one could just tap a word and its translation would appear within the text. This would save the learner from having to search for the word in an external dictionary or manually having to type it into a service like Google Translate. Keeping track of all the translations a user needs opens many opportunities for developing automated solutions that improve language learning.

In this thesis we introduce the idea of an application which offers a platform where users can improve a language of their preference by reading articles they like in this language. The application allows users to read articles from their favorite news and blogs websites in the language they want to learn as opposed to static and inflexible texts. Users are able translate unknown words by the simple tapping of a word. The word is pronounced and its translation is inserted in the text. The idea is implemented in the form of the Zeeguu Reader for iOS.
title: Ultrasound Based Measures of Muscle Fatigue and Recovery After Electrical Muscle Stimulation
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2022
Subjects: subject: Electrical muscle stimulation
subject: Fatigue recovery
subject: Human machine interface
subject: Muscle fatigue
subject: Bioengineering
subject: Medical imaging
subject: Biomedical engineering

description: Electrical muscle stimulation (EMS) can restore or increase function in skeletal muscle by stimulating motor neurons through adhesive skin electrodes, which can greatly increase the quality of life for those suffering from paralysis. However, the unnatural muscle fiber recruitment pattern from EMS causes muscles to fatigue and lose force rapidly, which limits the utility. Although technologies such as external exoskeletons exist to supplement muscle function, there is an open need for muscle fatigue feedback to gauge muscle strength in freely moving humans for EMS applications, as the current gold standard for measuring muscle fatigue, surface electromyography (sEMG), is generally incompatible. I believe that Doppler ultrasound will provide a better solution with fast (millisecond) time resolution, depth resolved measurements, and compatibility with EMS. Further, Doppler ultrasound provides information that is both independent of and complementary to sEMG and has utility outside of EMS applications in the fields of biomechanics, sports science, rehabilitation, and beyond.In this work, I explored signs of muscle fatigue and recovery induced by EMS using tissue Doppler imaging (TDI) with a bulky commercial ultrasound machine to establish the feasibility of this method. With this setup, I found that recovery in muscle twitch toque can be predicted from features of the average tissue velocity waveform, and that this model is subject specific. Next, for a portable solution, I performed experiments using a low power continuous wave (CW) ultrasound probe. The CW probe is portable, low power, and has much lower computational and memory requirements than the commercial TDI machine. For these experiments, I observed that the duration of audio signal at the onset of muscle contraction correlates with the peak join torque (a proxy for muscle force), and that audio signals are generated at both the onset and the release of muscle contraction in both EMS and voluntary movements. Finally, I conclude this study with multi-scale muscle modeling using a modified Hill-type model to help understand and explain our observations and predict muscle behavior.
Introducing the ggseg R-package for brain segmentations
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2018
Subjects: Plots
Packages
Neuroimaging
R

description: Dr. Mowinckel's blog: **Edit**: Though posted only a week ago, we have discovered another R package called `ggBrain` which has slightly different functions than what our package has. Because of this, we have altered the name of our package to `ggseg` short for `ggsegmentation` which is a better description of what our package does.   I've not written a post in a while. Mostly because of summer vacation, and also because I have been a little swamped at work. Fortunately, I got back to work with new gusto in August, and have something exciting to show you!
Supplementary document for Analytical model of a diode-pumped cesium laser for investigation of upper-state mixing and quenching reactions - 6355154.pdf
Creators: name: Endo, Masamori
name: Nagaoka, Hiroki
name: Wani, Fumio
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental document
The impact of future technological advancements on current bovine respiratory disease management practices
Creators: name: Nickell, Jason S.
name: Bryant, Lonty K.
name: Lavan, Robert P.
name: Rodríguez Fernandez, Pedro
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: technology
BRD
management practices
bovine respiratory disease

description: New technologies have aided the animal-based food and fiber industries to efficiently produce safe and valuable products for the human population. We strongly support appropriate use of currently available technologies designed to prevent, control, and treat BRD (e.g. vaccines, antimicrobials) as well as the ongoing implementation of management practices designed to reduce BRD risk (e.g. preconditioning strategies). However, we look forward to the application of new developments that optimize BRD prediction and diagnostic accuracy. These new tools may provide opportunities to maximize the efficacy of current prevention, control, and treatment modalities while also fostering in new opportunities to leverage non-antimicrobial options. The overall objectives being to maximize the producer’s bottom line and the animal’s wellbeing while satisfying consumer demand.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
Efficacy of a modified-live IBR-BVD-PI3-BRSV-Mannheimia haemolytica toxoid vaccine against challenge with virulent BHV-1 and PI3 viruses in calves 60 days of age
Creators: name: Masic, Aleksandar
name: Mahan, Suman
name: Sobecki, Brian
name: Brice, Chadwick
name: Mattern, Sally
name: Peterson, Dennis
name: Barret, Peter
name: Daugherty, Colt
name: Meinert, Todd
name: Ignacio, Correas
name: Véronique, Moulin
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: bovine
BHV-1
BRD
PI3
toxoid
5-way viral vaccine

description: Efficacy of attenuated (att) bovine herpesvirus type 1 (BHV-1) and bovine parainfluenza type-3 (PI3) viruses as antigen fractions in a modified-live virus (MLV) multivalent vaccine was evaluated following single, subcutaneous (SC) administration and intranasal (IN) challenge 28 days after vaccination, with either virulent BHV-1 or PI3 viruses in young calves. A total of 80 seronegative calves, 50 to 63 days of age at the time of vaccination, were used in 2 separate studies with 40 animals per study. Calves were allocated to 2 treatment groups with 20 animals per group which received either a single dose of a MLV IBR-BVD-PI3-BRSV vaccine, Mannheimia haemolytica toxoid, or corresponding placebo formulation without targeted test antigen fractions attBHV-1 (Study 1) or attPI3 (Study 2). Incidence and duration of clinical signs associated with respiratory disease, rectal temperatures, virus shedding, and serologic responses were compared between treatment groups in each study to assess vaccine efficacy. The 5-way vaccine induced significantly higher (p<0.0001) virus neutralizing antibody responses and reduction in fever (p<0.0001), mean rectal temperatures, and lower incidence or shorter duration of clinical disease related to BHV-1 and PI3 infection than placebo-treated calves. Infectious bovine rhinotracheitis (IBR) disease, hallmark of BHV-1 infection, was observed in 95% of control calves and in only 10% of vaccinates. Vaccinated animals in Study 1 and Study 2 demonstrated a 98.8 and 98.9% reduction in virus shedding, respectively, and significantly (p<0.0001) shorter duration of virus shedding compared to control calves, demonstrating protective vaccine efficacy.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
Metaphylaxis with tildipirosin did not inhibit effectiveness of an experimental monovalent vaccine of live, attenuated Mannheimia haemolytica administered intranasally to dairy calves
Creators: name: Nordstrom, Scott
name: Bolton, Michael
name: Hill, Kevin
name: Parks, Tim
name: Vaidyanathan, Mani
name: Vertenten, Geert
name: Lechtenberg, Kelly
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: bacterial vaccine
Mannheimia
interference
tildipirosin
immunization
lung lesions
bovine respiratory disease model

description: The objective of this study was to evaluate the effect of tildipirosin on the efficacy of a concurrently administered experimental vaccine against Mannheimia haemolytica. The experimental vaccine was developed for intranasal (IN) administration and contained the same live, attenuated, streptomycin-dependent Mannheimia haemolytica, at the same titer as in commercial product(s). Eighty-eight 14-week-old Holstein or Holstein-cross male calves from a single source were randomly assigned (using a 2 x 2 factorial design) to 1 of 4 treatment groups (22 head per group) as follows: 1) experimental vaccine (VAX) (IN); 2) VAX (IN) + tildipirosin subcutaneously (SC); 3) placebo vaccine (PLBO) (IN) as negative control; and 4) PLBO (IN) + tildipirosin (SC). Seventy days after enrollment, 84 calves were challenged with virulent M. haemolytica. Clinical assessment of each calf was recorded daily after challenge. There was no significant (P > 0.05) effect of any experimental treatment on clinical signs. Seven days after challenge, the calves were euthanized, a percent lung lesion score (LLS) was assigned to each, and samples of lung were submitted for isolation of M. haemolytica. There was no significant (P = 0.51) effect of tildipirosin on LLS for calves vaccinated with VAX or those vaccinated with PLBO; however, VAX resulted in significantly (P = 0.046) lower LLS. Under the conditions of this study, concurrent administration of tildipirosin and IN live, attenuated, streptomycin-dependent M. haemolytica vaccine with the same antigen as used in this study did not interfere with the efficacy of the vaccine.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
Progesterone release and incidence of bacteria following disinfection and reuse of controlled internal drug release devices (CIDRs)
Creators: name: Talsma, B.
name: Fields, B. J.
name: Vincent, K. L.
name: Smith, W. B.
name: Speshock, J. L.
name: Waddell, J.
name: Snyder, D.
name: Dias, N. W.
name: Mercadante, V. R. G.
name: Jones, T.
name: Roper, D. A.
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: progesterone
bacteria
reuse
CIDR

description: Controlled internal drug release (CIDR) devices have been reused in cattle estrous synchronization protocols. However, the effectiveness of the CIDR and incidence of vaginal bacteria secondary to reuse remains unclear. Therefore, 2 experiments were conducted to evaluate plasma progesterone and vaginal bacteria utilizing used CIDRs disinfected prior to reuse. In Exp. 1, cows received a new CIDR (CONT) or a used CIDR disinfected by 1 of 3 methods: autoclaved (AUTO), dishwasher (DISH), or chlorhexidine (CHLO). No difference was detected in plasma progesterone (P = 0.24) concentration between treatment groups. Daily progesterone concentrations differed during CIDR treatment (P < 0.001) on d 0, 3, and 7. In Exp. 2, vaginal mucous samples were collected pre- and post-synchronization. Cows received CONT, AUTO, or CHLO treated CIDRs. Bacterial loads in vaginal mucus cultured on TSA blood agar did not differ by treatment (P = 0.29) nor by day (P = 0.69). CHLO-treated CIDRs had higher bacterial gram-negative colony counts than those disinfected with AUTO or CONT (P = 0.0035), and bacterial load was higher on d 7 than d 0 (P = 0.0025) for vaginal mucous samples cultured on EMB agar. Based on the results of these studies, twice-used treated CIDRs do not reduce progesterone plasma concentrations, however, risk of bacterial contamination of the vagina must be considered.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
Scrotal circumference at weaning in beef bulls and subsequent ability to pass a breeding soundness examination as a yearling
Creators: name: Fountain, Tara H.
name: Larson, Robert L.
name: White, Brad J.
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: bull
scrotal circumference
breeding soundness examination
BSE

description: Identifying bulls at weaning with higher likelihood of
passing a breeding soundness examination as yearlings may
improve management options to optimize production efficiency.
The objective of this study was to evaluate the effect of weaning scrotal circumference and other factors collected at the time of weaning on the likelihood of passing a breeding soundness examination as a yearling. Data, at both weaning and time of breeding soundness examination, were collected from 1 operation (n = 466 bulls). A logistic regression model was used to evaluate the potential associations of relevant factors (actual weaning scrotal circumference, adjusted weaning scrotal circumference, weight per day of age at weaning, scrotal circumference per day of age at weaning, weaning weight, and breed) on the probability of passing a breeding soundness examination as a yearling. Overall, 92.3% of bulls passed the yearling breeding soundness examination on first evaluation. Weaning scrotal circumference was the only factor of those evaluated associated (P < 0.01) with the probability of passing the breeding soundness examination. No significant differences were found between the categories of weaning scrotal circumference. In the future, more research needs to evaluate predictive model development for weaning scrotal circumference and ability to pass breeding soundness examination.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
British Columbia and Vancouver's Island : comprising a description of these dependencies, their physical character, climate, capabilities, population, trade, natural history, geology, ethnology, gold-fields, and future prospects, also an account of the manners and customs of the native Indians
Creators: name: Macdonald, Duncan George Forbes, 1823?-1884
Publisher: name: London : Longman, Green, Longman, Roberts, & Green
Year: 2016

Abstract
Supplementary document for Longitudinal Tracking of Perfluorooctanoic Acid Exposure on Mammary Epithelial Cell Spheroids by Dynamic Optical Coherence Tomography - 7104689.pdf
Creators: name: Yang, Lin
name: Ji, Pan
name: BUZETTA, Abel Miranda
name: Lockett, Matthew
name: Oldenburg, Amy
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Optical Technology

description: Revised Supplement 1 with Figs S1-S4 and Table S1
title: Paper: Nancy Larsoy, "RCA's Role For 1989 -90 and Beyond," Undated
Creators: name: Larsoy, Nancy
Publisher: name: George Mason University
Year: 2007
Subjects: subject: Reston (Va.)
subject: Reston Community Association

description: Textual: paper, original; 11” x 8.5” (27.9 cm x 21.6 cm)
description: Paper by the Nancy Larsoy entitled "RCA's Role For 1989 -90 and Beyond" that is undated. Larsoy discusses the future of the Reston Community Association in this paper. Mainly, Larsoy is discussing her desire for a new focus for the organization. She believes that new plans should be created for Reston, Virginia. She also suggests RCA should lead the way for creating new goals for Reston. Specifically she wants RCA to facilitate communication among the various groups in Reston to aide in the creation these new goals. Planned Community Archives Collection, mcd4.10
Supplementary document for All-day uninterrupted thermoelectric generator by simultaneous harvesting of solar heating and radiative cooling - 6355876.pdf
Creators: name: Liu, Jing
name: Li, Degui
name: Ma, Wenzhuang
name: Chen, Yushan
name: Dou, Chao
name: meng, dan
name: He, Qiyao
name: Li, Xiangyu
name: deng, xuchu
name: Cai, Haoyuan
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary Material for 483531
Influence of bovine viral diarrhea virus infections on AI conception and breeding season pregnancy success in vaccinated beef herds
Creators: name: Epperson, Kaitlin M.
name: Rich, Jerica J. J.
name: Zoca, Saulo Menegatti
name: Perkins, Stephanie D.
name: Northrop, Emmalee J.
name: Daly, Russell F.
name: Walker, Julie A.
name: Rhoades, Jim R.
name: Perry, George A.
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: words: bovine viral diarrhea virus
pregnancy success
vaccination

description: Bovine viral diarrhea virus (BVDV) causes reproductive and economic losses in cattle. The objective of this study was to evaluate the influence of BVDV infections on reproductive success in previously vaccinated herds. Vaccinated cows (n=370) and heifers (n=528) from 9 herds were synchronized and artificially inseminated (AI). On d 28 following insemination, blood samples were collected and pregnancy status was determined. Non-pregnant animals were resynchronized and inseminated a second time. Blood samples were tested for the presence of BVDV antigen. Animals that tested positive were considered infected with BVDV. Herds with at least 1 positive animal were determined to be BVDVinfected (n=4 infected, n=5 non-infected). Statistical analyses were performed using the GLIMMIX procedure of SAS with herd as a random variable. Herds with BVDV infections at d 28 had significantly decreased (P < 0.01) AI conception rates compared to non-infected herds (34 ± 2.3% vs 56 ± 2.3%). Breeding season pregnancy rates were also decreased (P < 0.01) in BVDV-infected herds compared to non-infected herds (68 ± 3.1% vs 88 ± 6.9%). In conclusion, BVDV infections in previously vaccinated herds had a negative impact on AI conception rates and breeding season pregnancy success.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
SCIENCE IN HUNGARY and HUNGARY IN SCIENCE
Creators: name: HARGITTAI, Istvan
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: In this invited presentation, I will attempt to give a bird’s eye view of the relationship between Hungary and science. A group of aristocrats founded the Hungarian Academy of Sciences in 1825. Following the defeated Revolution and War for Independence of 1848‒49 and the ensuing suppression, the Compromise with the Habsburgs in 1867 opened an era of unprecedented progress in Hungary. One of its products was an outstanding network of high schools (secondary schools), cradles of creativity, whose graduates eventually earned Nobel Prizes and enriched world culture and science.

World War I, the revolutions, and the autocratic and anti-Semitic Horthy era (1920‒1944) resulted in an exodus of talent and the Holocaust further decimated the country’s scientific potentials. Then, the oppressive Soviet-style political system was moving toward gradually relaxing restrictions, and allowed a certain degree of productivity in science (1948‒1989).

Two decades of fledgling democracy (1990‒2010) brought about increasing competition for science for the best talents among several fields. Sadly, the current autocratic governance has caused another exodus of talent. Low-level of support for science has been characteristic for a long time in contrast with the plethora of scientific achievements, but the latter is a sum of performance at home and abroad. It is already a century that both resident and émigré scientists have been winning well-deserved recognition for their exceptional contributions. For illustration, let us have a few names. János Bolyai expanded geometry beyond its Euclidean foundations. Ignác Semmelweis—the “Savior of Mothers”—was a founder of medicinal antisepsis. Loránd Eötvös constructed his famous pendulum and paved the way for the theory of general relativity. George de Hevesy used radioactive labeling to follow chemical and biochemical processes. Albert Szent-Györgyi made fundamental discoveries in biochemical energetics. George A. Olah induced the un-reactive covalent bond to become reactive in super- acidic environment. The “Martians of Science,” Theodore von Kármán, Leo Szilard, Eugene P. Wigner, John von Neumann, and Edward Teller, in addition to making fundamental discoveries in the physical sciences and computation, defended the Free World against totalitarian regimes. The list could be continued; and take one more example from a far away endeavor: Béla Bartók was not only a composer and concert pianist, but a great scholar in musicology.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Comparison of three injectable metaphylactic antimicrobial treatments administered at feedlot arrival for control of bovine respiratory disease in calf-fed Holstein steers
Creators: name: Buchanan, Justin W.
name: Nilles, Ashley R.
name: Raymond, Randall C.
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: bovine respiratory disease
calf-fed Holstein
metaphylactic antimicrobials
feedlot morbidity
dairy calves

description: Three injectable metaphylactic antimicrobials were evaluated for efficacy against bovine respiratory disease (BRD) in calf-fed Holstein steers. Calves (N=3,605) weighing between 210 and 580 lb (95 and 263 kg) were enrolled in a complete random study design and administered either tulathromycin (TUL, 1.1 mL/100 lb [45.4 kg] of body weight [BW]), tildipirosin (TPR, 1.0 mL/100 lb [45.4 kg] BW), or gamithromycin (GAM, 1.8 mL/100 lb [45.4 kg] BW) at feedlot arrival. Body weight, health events, and carcass data were collected to assess differences among experimental groups for morbidity, mortality, treatment success, realizer rate, average daily gain (ADG), and carcass traits. An economic model was developed to compare the relative economic outcome associated with metaphylaxis using parameters describing morbidity, relapse, realizer, and mortality rates as well as the individual drug cost. No significant differences (P>0.05) were observed for ADG, first-pull morbidity rate, mortality rate, carcass weight, backfat, or marbling score due to metaphylaxis across experimental groups. Calves administered gamithromycin at processing had a significantly lower (P=0.01) realizer rate and realizer plus mortality rate, and higher (P=0.02) first-treatment success rate compared to calves administered tulathromycin. Health and performance outcomes did not differ between calves in the GAM and TPR groups; however, drug cost was lower in the GAM group. Compared to calves in the TUL group, the economic benefit of metaphylaxis was greater for calves in the GAM experimental group when considering drug cost and difference in relapse, realizer, and realizer plus mortality rates.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
Supplementary document for Longitudinal Tracking of Perfluorooctanoic Acid Exposure on Mammary Epithelial Cell Spheroids by Dynamic Optical Coherence Tomography - 7132248.pdf
Creators: name: Yang, Lin
name: Ji, Pan
name: BUZETTA, Abel Miranda
name: Li, Haolin
name: Lockett, Matthew
name: Zhou, Haibo
name: Oldenburg, Amy
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Optical Technology

description: Supplemental Document 1
Comparison of gamithromycin post-treatment intervals for beef cattle naturally affected with bovine respiratory disease
Creators: name: Theurer, Miles E.
name: Fox, J. Trent
name: Portillo, Tom A.
name: Meyer, Nathan F.
name: Ensley, Douglas T.
name: Renter, David G.
Publisher: name: The Bovine Practitioner
Year: 2020
Subjects: BRD
dairy-beef cross
feedlot
PTI
treatment
gamithromycin

description: The primary objective of this study was to compare different gamithromycin post-treatment intervals (PTI) on clinical health outcomes in cattle naturally affected with bovine respiratory disease (BRD). Eight hundred cattle identified with BRD by pen riders, rectal temperature ≥ 104.0°F (≥ 40°C), and no previous treatments were randomized in a 1:1:1:1 ratio to 3-, 6-, 9-, or 12-day PTI within each lot. Cattle treated for BRD were returned to their home pen, and followed for 60 days (d) to monitor subsequent health outcomes. Cattle were categorized by type (dairy-beef or native). General and generalized linear mixed models were used for statistical analyses. First treatment success (P = 0.012) and BRD case fatality risk (P = 0.032) were different among PTI groups. The 9-d PTI group had the greatest first treatment success, which was different (P = 0.008) than the 3-d PTI. The 12-d PTI group had the poorest BRD case fatality risk, which was different (P = 0.071) than the 9-d PTI group. There were no significant differences between the 6- and the 9-d PTI groups. Dairy-beef cattle had an approximately 2-fold higher BRD case fatality risk (P = 0.012) than natives. Results will help practitioners to optimally use gamithromycin in the field.
description: The Bovine Practitioner, Vol. 54, No. 2 (2020)
title: An Integrated QoS Metric for Handoff Decisions in 5G and LTE Networks
Creators: name: Sandhya Rani Siva Raju, Srinivas
Publisher: name: George Mason University
Year: 2018
Subjects: subject: Handoff decisions
subject: Simple Additive Weighting (SAW)
subject: MmWave propagation
subject: NS3

description: Growing demand for wireless data and the spectrum congestion in the existing 4G LTE networks have led the researchers to focus on ways to utilize the large bandwidths available in the above 6 GHz spectrum. The technology that would be implemented in this spectrum has been termed as 5G is expected to roll out by the year 2020. While many models have been proposed and researched on the implementation of 5G, relatively less work has been done on one of the crucial aspects of cellular communications: handoffs. Handoff is the process of transferring connection of a mobile user from one node to another, when the previous node cannot provide proper service. Current handoffs are performed, based on the signal strength. In this process, as the signal from the current node drops, the user then has to connect the node to a higher signal strength. While this method could work in micrometer wave spectrum, the propagation characteristics of a signal are different in the millimeter wave spectrum. Frequent drops in the signal level, even due to the user movement would mean that number of handoffs performed would be very high and would also lead to the ping-pong effect. To avoid this, the use of an integrated QoS metric for the handoff decision has been proposed. In this method the handoff is performed not based on the signal strength level but by considering past values of the each base station has been made. For the weighting criteria the normalized variance of SINR values of each base station, and the probability of missed detection has been considered. This ensures that the mobile user would connect to a more stable base station thus avoiding frequent unnecessary handoffs. A simulated approach has been taken to compare the performance of the weighted handoff with the traditional signal strength approach based handoff. The simulations were done in a 5G radio propagation framework using Matlab and in the LTE model of the Network Simulator 3 (NS3) software. The results show that the number of handoffs performed were lesser in the weighted handoff as compared to the traditional handoff, which was observed in both the 5G propagation simulation in Matlab and in the LTE model of NS3. In addition to this, analysis on the effects the weighted handoff would have on different network QoS parameters-the mean delay, the packet loss ratio and sum of jitter, has been done on NS3 LTE. Results show that the new algorithm doesn't just abide by the LTE QoS, but also shows an improvement.
INTRODUCTORY LECTURE: THE HISTORY OF REDOX BIOLOGY, FROM « REDUKTONE » OF HANS VON EULER TO FREE RADICALS EXAMPLIFIED BY THE MAILLARD REACTION, THE ELASTIN RECEPTOR AND ATHEROGENESIS
Creators: name: ROBERT, Ladislas
name: LABAT-ROBERT, Jacqueline
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Redox processes play an important role in Biochemistry but they are also involved in the generation of a variety of pathologies. Organic chemists as Hans von Euler realised the importance of redox processes. He described strongly reducing molecules called « reduktones » and « reduktonates » examplified by Triose reduktone and also ascorbic acid discovered at about the same time by Szent-Gyorgyi. The possibility and importance of single electron transfer creating Free Radicals did not penetrate organic chemistry at the same time although discovered by physical chemists in the late years of the XIXth century, one example is the Fenton reaction (1894) and the Maillard reaction (1912). To a large part, the chemistry and biology of redox processes are based on the exceptional properties of oxygen which will be reviewed. The age-dependent increase of vascular pathology is also an example which will be discussed. The degradation of Elastin liberates elastin peptides which activate the elastin receptor with release of elastases and Free Radicals. Elastin peptides produce oxidative burst on monocytes with Free Radical release and apoptotic cell death. The presence of the Elastin receptor on fibroblasts and smooth muscle cells further confirms the importance of these processes in age-related vascular pathologies.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
title: Travel Behavior Reactions to Transit Services Disruptions: A Case Study on the Washington D.C. Metro SafeTrack Project
Creators: name: Masud, Hamza
Publisher: name: George Mason University
Year: 2019
Subjects: subject: Transit network disruption
subject: WMATA SafeTrack
subject: Behavioral reactions
subject: Hierarchical travel choice model
subject: Travel surveys
subject: Travel choice responses

description: Major transit infrastructure disruptions have become more frequent due to increasing maintenance needs for an aging infrastructure, system failures, and disasters. Understanding travel behavior reactions to service disruptions based on empirical observations is a fundamental step toward planning and operating an efficient and reliable transportation system. Few studies in the literature investigated the behavioral and system impact of transit service disruptions. To bridge this gap in literature, this research investigated travel behavioral reactions to transit service disruptions during the Washington D.C. Metro SafeTrack projects using a unique panel survey. This study will offer new insights on multi-modal, multi-dimensional travel behavioral responses to major transit network disruptions, a critically theoretical prerequisite toward developing and implementing effective strategies (e.g., how to optimally deploy the reserved bus fleet) that minimize system impact and improve transit system reliability and resiliency.
British Columbia and Vancouver's Island : comprising a description of these dependencies, their physical character, climate, capabilities, population, trade, natural history, geology, ethnology, gold-fields, and future prospects : also an account of the manners and customs of the native Indians
Creators: name: Macdonald, Duncan George Forbes, 1823?-1884
Publisher: name: London : Longman, Green, Longman, Roberts, & Green
Year: 2015

Abstract
EXTRACELLULAR MATRIX GLYCATION, REDOX STATUS AND CROSS-LINKING
Creators: name: RICARD-BLUM, Sylvie
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Extracellular matrix (ECM) is mostly comprised of proteins and proteoglycans, which form supramolecular assemblies. It provides shape and mechanical properties - mediated by covalent cross-links - to tissues and organs, and regulates cell behavior. Covalent cross-linking of the ECM is mediated by transglutaminase-2, glycation and more specifically by enzymes of the lysyl oxidase family. Lysyl oxidase, or protein-lysine 6-oxidase, contains the redox cofactor lysyl-tyrosine quinone and is a source of hydrogen peroxide, a reactive oxygen species. We have investigated ECM cross-links formed via glycation and lysyl oxidase in liver and skin fibrosis and we are currently building the interaction network of lysyl oxidase to determine if it plays further biological roles in ECM and in pericellular matrix at the cell surface.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Supplementary document for Coulomb potential determining terahertz polarization in two-color laser field - 6355954.pdf
Creators: name: Gao, Yuan
name: Zhang, Yizhu
name: Zhang, Kaixuan
name: gan, ziyang
name: YAN, T.-M.
name: JIANG, Y. H.
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Experimental Setup
DELAYED INTERVENTION WITH PYRIDOXAMINE IMPROVES METABOLIC FUNCTION AND PREVENTS ADIPOSE TISSUE INFLAMMATION AND INSULIN RESISTANCE
Creators: name: SCHALKWIJK, Casper G
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The development of obesity is one of the largest health problems worldwide. We and others have recently demonstrated that advanced glycation endproducts (AGEs) accumulate in adipose tissue, and that they contribute to complications such as insulin resistance and type 2 diabetes via an inflammatory reaction in adipose tissue. We recently investigated the effect of a delayed PM intervention on metabolic and vascular function in high-fat diet (HFD)-induced obese mice. We found that PM-treated, HFD-induced obese mice had reduced body weight gain, hyperglycemia and hypercholesterolemia, as compared to those who were not treated with PM. Furthermore, PM treatment inhibited the expansion of adipose tissue and adipocyte hypertrophy. Adipogenesis of murine 3T3-L1 and human SGBS preadipocytes was dose-dependently reduced by PM treatment. The high expression of pro-inflammatory genes in visceral adipose tissue of the HFD group was significantly attenuated by PM. In both HFD-induced and db/db obese mice, impaired glucose metabolism and insulin resistance were prevented by supplementation with PM. Moreover, PM treatment partially prevented HFD-induced mild vascular dysfunction.
In conclusion, we will discuss AGEs in obesity and will demonstrate that a delayed intervention with PM is associated with an improvement of several aspects of obesity, including metabolic dysfunction, insulin resistance and adipose tissue inflammation. These findings indicate that PM may be a potential novel intervention strategy for obesity-associated metabolic dysfunction and complications.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
SKIN COLLAGEN PENTOSIDINE AND FLUORESCENCE IN DIABETES ARE PREDICTORS OF CREATININEMIA INCREASE AND RETINOPATHY PROGRESSION ALREADY 6 YEARS AFTER PUNCH-BIOPSY
Creators: name: STERNBERG, Michel G
name: M'BEMBA, Jocelyne
name: URIOS, Paul
name: BORSOS, Anne-Marie
name: SELAM, Jean-Louis
name: PEYROUX, Jacques
name: SLAMA, Gérard
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: We measured pentosidine and fluorescence at 370/440nm in collagen extracted from skin punch-biopsies in 30 patients with diabetes (14 type 1 diabetes and 16 type 2 diabetes) without renal insufficiency, and in age- and gender-matched normoglycemic controls, followed at Hôtel-Dieu in Paris. At the time of biopsy, marked increases in pentosidine and fluorescence levels, expressed per collagen hydroxyproline, were found in the patients with diabetes versus normoglcemic controls. Pentosidine and fluorescence were correlated with diabetes duration. Fluorescence was significantly dependent on retinopathy presence and score in type-1 and type-2 diabetes. Fluorescence was correlated with microalbuminuria, only in type-1 diabetes. Already six years after biopsy, retinopathy score progression and creatininemia increase were significantly correlated with initial pentosidine and fluorescence levels.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Return to an address of the honourable the House of commons, dated 13 July 1863, for copies or extracts of any correspondence between Mr. Langford and the Colonial Department, relative to alleged abuses in the government of Vancouver's Island
Creators: name: Fortescue, C.
name: Langford, Edward E.
name: Great Britain. Colonial Office
Publisher: name: [London] : Colonial Office
Year: 2016

Abstract
Analysis of Sastra dan Kuliner : Evolusi Gastronomi ke Gastrosofi dalam Tiga Cerpen Indonesia By Bramantio
Creators: name: Azanila Firsaty Ladya
Publisher: name: Zenodo
Year: 2022
Subjects: : starter dough, coffee, connotation, culinary, smoko

description: The purpose of the paper analysis is “Filosofi kopi” and “Madre” by Dee and “Sokol” by Nukila Amal are short stories that present culinary as a generator of its structures. Coffe, starter dough, and smokol (brunch in the tradition of Manado people) are not merely food and beverage. In the beginning, the stories seem to tell about the celebration of life, the efforts to get the best presentation and taste of food and beverage, and the understanding of personal identity, but then move into another direction, a point named contemplation of Indonesia. Those short stories are miniatures of Indonesia, itsIndonesiaits Indonesia is not the collapsed and gloomy one, but Indonesia with a better future because it has Ben, Tansen, and Batara as an urban young generation with awareness to accept, explore, and maintain their ancestor’s philosophical values.
GLYCATION OF LENS PROTEINS IN DIABETES and ITS NON-INVASIVE ASSESSMENT
Creators: name: ŠKRHA, Jan
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The accumulation of advanced glycation endproducts in the lens reflects total glycation rate in the human body. While this phenomenon has been known for many years, any quick and easy measurement of this lens glycation was missing. Recently, a new confocal biomicroscope non-invasively measuring lens autofluorescence and reflecting some AGEs accumulation has been developed. Our pilot study including 180 subjects compared lens autofluorescence and skin autofluorescence assessed by AGE-Reader. Both measurements were significantly higher in patients with diabetes and a significant relationship between lens and skin autofluorescence was observed. Lens autofluorescence could be a robust marker of long-term diabetes control predicting future complication risks. However, confirmation of such hypothesis will need other and long-term clinical studies.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
AMADORIASE ENGINEERED ENZYME FOR PROTEIN DEGLYCATION
Creators: name: RIGOLDI, Federica
name: DALLE VEDOVE, Andrea
name: VESENTINI, Simone
name: PARISINI, Emilio
name: GAUTIERI, Alfonso
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The progressive accumulation of Advanced Glycation End-product (AGEs) in the human body leads to several deleterious consequences, involving tissues stiffening and pathologies (aterosclerosis, nephropathy, and Alzheimer’s disease). Nowadays there are no effective therapies against AGEs build-up, although a promising strategy is redeglycating enzymes (FAOXs), which are however inactive towards entire proteins due to their buried active site.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
DIET-INDUCED ACCUMULATION OF AGES CONTRIBUTE TO METABOLIC DISEASES ONSET BY INTERFERING WITH SREBP-1C ACTIVITY
Creators: name: RIGOLDI, Federica
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Literature data have evidenced the diet-induced accumulation of Advanced Glycation End-Products (AGEs) associated to several dysmetabolic conditions, as obesity, insulin resistance, and type 2 diabetes. We have recently reported in different animal models of diet-induced metabolic disorders the causal link between AGEs and the dysregulated activation of the lipogenic transcription factor SREBP1c. We have thus analyzed in different target tissues of dysmetabolism the effect of the AGEs/SREBP1c axis overactivation on selective pathways involved in the antioxidant and inflammatory response, as well as in structural and metabolic adaptation. Our most recent findings have demonstrated that the inhibition of AGEs production by the administration of the anti- glycative compound pyridoxamine to mice fed a high-fat or high-fructose diet is able to prevent the AGEs/SREBP1c-depending impairments.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
THE ROLE OF HEMOGLOBIN DERIVED HEME IN THE PATHOGENESIS OF VASCULAR DISORDERS
Creators: name: BALLA, György
name: POTOR, László
name: HORVÁTH, Zsolt
name: NYITRAI, Mónika
name: BALLA, József
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: In the pathogenesis of several vascular disorder modified proteins and lipids generated by reactive oxygen species accumulate in the vessel wall resulted in atherosclerosis, calcification, neovascularization. Since transition metals are also accumulating in these pathologies, generating continuous free radical stress. We suggested that the source of iron is heme derived from modified hemoglobin. Using in vitro cell culture models and human vessel samples, we proved, that heme is an efficient free radical catalyst, toxic for cell membranes and lipoproteins leading to vessel injury. Next we tested several heme proteins as potential origins for heme. We proved that the main heme donor is the modified hemoglobin after red blood cell hemolysis. Hemoglobin is not only heme donor, but the modified globin also plays a role in vessel pathologies. We do not know yet whether glycation of hemoglobin has an effect on hemeprotein mediated vessel wall injury.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
EXERCISE AND BRAIN FUNCTION: IS IT REDOX REGULATED?
Creators: name: RADAK, Zsolt
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Regular exercise has systemic beneficial effects including the promotion of brain function. The adaptive response to regular exercise includes the up-regulation of the enzymatic antioxidant system, and modulation of oxidative damage. Reactive oxygen species (ROS) are important regulators of cell signaling and exercise through activity dependent modulation of metabolism and/or direct activation of ROS generating enzymes, thus, modulating the cellular redox state in the brain. ROS are also involved in the self-renewal and differentiation of neuronal stem cells and, as a result, exercise-mediated neurogenesis could be associated with ROS production. Exercise has a powerful effect on the immune system, and readily alters the production of cytokines. Certain cytokines, especially IL-6, IL-1, TNF-a, IL-18 and interferon gamma are actively involved in the modulation of synaptic plasticity and neurogenesis. Cytokines can also contribute to ROS production. ROS- mediated alteration of lipids, protein and DNA could directly affect brain function while exercise modulates the accumulation of oxidative damage. Oxidative alteration of macromolecules, to a moderate degree, can activate signaling processes. Hence, it could be part of the adaptive response to exercise training.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)
Bovine Practitioner Vol. 54, No. 1 (2019 Spring). Front matter
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 2020

description: Cover, Masthead, Table of Contents, and other editorial information.
description: The Bovine Practitioner, Vol. 54, No. 1 (2020 Spring)
SUPRA-ADDITIVE IMPACT OF MITOCHONDRIAL DYSFUNCTION AND SUBSEQUENT OXIDATIVE STRESS IN CENTRAL NERVOUS SYSTEM PATHOLOGY
Creators: name: SPERLAGH, Beata
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Mitochondrial dysfunction, oxidative stress and their interplay are core pathological features of neurodegenerative diseases. In Parkinson's disease (PD), mitochondrial dysfunction and oxidative stress have a supra-additive impact on the pathological, cytoplasmic accumulation of dopamine and its subsequent release. Moreover, dopamine and their metabolites provide an additional source of reactive oxygen species (ROS) during their breakdown by monoamine oxidase or auto-oxidation. Therefore those drugs which simultaneously target mitochondrial dysfunction, oxidative stress and subsequent pathological dopamine release may have disease- modifying potential in addition to symptomatic improvement by the blockade of self-amplifying circuits leading to ROS generation.
To fulfill this aim we have developed a novel series of potent and selective MAO-B inhibitory (hetero)arylalkenylpropargylamine compounds having also protective properties against the supra-additive effect of mitochondrial dysfunction and oxidative stress. The compounds were tested in a wide range of in vitro and in vivo toxin-induced animal models of PD. The compounds exhibited consistent protective effects against i) in vitro oxidative stress induced pathological dopamine release and the formation of toxic dopamine quinone in the rat striatum and rescued dopaminergic neurons; ii) in vivo MPTP-induced striatal dopamine depletion and motor dysfunction in mice using acute, subchronic, and chronic protocols. In conclusion the above strategy seems a plausible approach to halt the progressive loss of nigrostriatal dopaminergic neurons and to combat PD.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016)