cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cytomegalovirus Downregulates IRE1 to Repress the Unfolded Protein Response
Creators: name: Stahl, Sebastian
name: Burkhart, Julia M.
name: Hinte, Florian
name: Tirosh, Boaz
name: Mohr, Hermine
name: Zahedi, René P.
name: Sickmann, Albert
name: Ruzsics, Zsolt
name: Budt, Matthias
name: Brune, Wolfram
Publisher: name: Robert Koch-Institut
Year: 2013
Subjects: subject: Animals
subject: Humans
subject: Mice
subject: DNA-Binding Proteins/genetics
subject: DNA-Binding Proteins/metabolism
subject: Membrane Proteins/genetics
subject: Transcription Factors/genetics
subject: Transcription Factors/metabolism
subject: Cytomegalovirus/genetics
subject: Cell Line Transformed
subject: Cytomegalovirus/metabolism
subject: Cytomegalovirus Infections/genetics
subject: Cytomegalovirus Infections/metabolism
subject: Down-Regulation/genetics
subject: Endoribonucleases/biosynthesis
subject: Endoribonucleases/genetics
subject: Membrane Proteins/biosynthesis
subject: Muromegalovirus/genetics
subject: Muromegalovirus/metabolism
subject: NIH 3T3 Cells
subject: Protein-Serine-Threonine Kinases/biosynthesis
subject: Protein-Serine-Threonine Kinases/genetics
subject: Unfolded Protein Response
subject: Viral Structural Proteins/genetics
subject: Viral Structural Proteins/metabolism
subject: 610 Medizin

description: During viral infection, a massive demand for viral glycoproteins can overwhelm the capacity of the protein folding and quality control machinery, leading to an accumulation of unfolded proteins in the endoplasmic reticulum (ER). To restore ER homeostasis, cells initiate the unfolded protein response (UPR) by activating three ER-to-nucleus signaling pathways, of which the inositol-requiring enzyme 1 (IRE1)-dependent pathway is the most conserved. To reduce ER stress, the UPR decreases protein synthesis, increases degradation of unfolded proteins, and upregulates chaperone expression to enhance protein folding. Cytomegaloviruses, as other viral pathogens, modulate the UPR to their own advantage. However, the molecular mechanisms and the viral proteins responsible for UPR modulation remained to be identified. In this study, we investigated the modulation of IRE1 signaling by murine cytomegalovirus (MCMV) and found that IRE1-mediated mRNA splicing and expression of the X-box binding protein 1 (XBP1) is repressed in infected cells. By affinity purification, we identified the viral M50 protein as an IRE1-interacting protein. M50 expression in transfected or MCMV-infected cells induced a substantial downregulation of IRE1 protein levels. The N-terminal conserved region of M50 was found to be required for interaction with and downregulation of IRE1. Moreover, UL50, the human cytomegalovirus (HCMV) homolog of M50, affected IRE1 in the same way. Thus we concluded that IRE1 downregulation represents a previously undescribed viral strategy to curb the UPR.
Supplemental Material, sj-docx-1-jrc-10.1177_00224278211023988 - The Age-Graded Consequences of Justice System Involvement for Mental Health
Creators: name: Powell, Kathleen
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-docx-1-jrc-10.1177_00224278211023988 for The Age-Graded Consequences of Justice System Involvement for Mental Health by Kathleen Powell in Journal of Research in Crime and Delinquency
Supplemental Material, sj-pdf-1-jrc-10.1177_00224278211023988 - The Age-Graded Consequences of Justice System Involvement for Mental Health
Creators: name: Powell, Kathleen
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-1-jrc-10.1177_00224278211023988 for The Age-Graded Consequences of Justice System Involvement for Mental Health by Kathleen Powell in Journal of Research in Crime and Delinquency
Body-Mind-Spirit Paradigm - Genetic Emotion-Charged Unconscious Spiritual Symbols!: Native American tribes, Hawaiian Ho'omana, + indigenous Filipino tribes Ifugao social order (R Reyes) T'boli beliefs + Filipino Kapwa (shared-identity) & Ginhawa,
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2024
Subjects: subject: Spirituality
subject: Blaan (Philippine people)
subject: New Age movement
subject: Spirituality--Christianity
subject: Indians of North America
subject: Tboli (Philippine people)
subject: Indigenous peoples
subject: Ethnology
subject: Culture
subject: Psychology
subject: FOS: Psychology

description: Among Native American cultures, there appears to have been a nearly universal acceptance of the concept of "spirit-life-force" intrinsic to the world, nature and people, pervasive in the Native American culture. For instance, the Sioux embraced the concept of wakd or mahopa; the Algonquin, the idea of manitowi; the Mahopa Shoshone used the word pukunt. Across the Iroquois tribes, the concept was referred to variously as orenna or karenna by the Mohawk, Cayuga, and Oneida, urente by the Tuscarora, and iarenda or orenda by the Huron. Orenda (or orenna) is an Iroquois name for a spiritual power intrinsic to people and the world. The world and nature were viewed as an eternal struggle of one orenda against others. The role of orenda was viewed in ways similar to the Judeo-Christian tradition (as well as Islamic) in which the Holy spirit was the source and force for prophecy, divination, miracles, blessing, prayer, and worship.
The T'boli had similar views. "Fu, the spirit of the land, has a dual character. At times benevolent, that Fu would help people especially farmers by blessing them with bountiful harvests or healing the sick member of a family, malevolent, in other times, that Fu causes illness and destroys crops. Understanding on the duality of the spirit's characteristics gives each T'boli reverence to the environment that extends to the different elements that communes with it. In fact, trees, animals, and water are not considered as mere elements but other spiritual [living] entities.
This belief system guides them to commune with nature and all entities that co-exist from it. From this belief, they anchor their respect and regard to all things that exist. They conserve, protect, and manage their natural resources like how they treat their relationship to each other.
Supplemental Material, sj-pdf-2-jrc-10.1177_00224278211023988 - The Age-Graded Consequences of Justice System Involvement for Mental Health
Creators: name: Powell, Kathleen
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-2-jrc-10.1177_00224278211023988 for The Age-Graded Consequences of Justice System Involvement for Mental Health by Kathleen Powell in Journal of Research in Crime and Delinquency
II Paradigma Cuerpo-Mente-Espíritu - ¡Símbolos espirituales inconscientes cargados de emociones genéticas!: Tribus nativas americanas, Ho'omana hawaianas, + tribus indígenas filipinas Orden social Ifugao (R Reyes) Creencias T'boli + Kapwa filipino
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2024
Subjects: subject: Latin poetry
subject: Hispanic Americans--Ethnic identity
subject: Hispanic Americans
subject: Hispanic American women
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Indigenous peoples
subject: Ethics
subject: Art, South American
subject: Spanish poetry
subject: Philosophy, Spanish

description: Entre las culturas nativas americanas, parece haber habido una aceptación casi universal del concepto de "espíritu-fuerza vital" intrínseco al mundo, la naturaleza y las personas, omnipresente en la cultura nativa americana. Por ejemplo, los sioux adoptaron el concepto de wakd o mahopa; el Algonquin, la idea de manitowi; los Mahopa Shoshone usaron la palabra pukunt. Entre las tribus iroquesas, los mohawk, cayuga y oneida se referían al concepto como orenna o karenna, urente por los tuscarora y iarenda u orenda por los hurones. Orenda (u orenna) es un nombre iroqués para un poder espiritual intrínseco a las personas y al mundo. El mundo y la naturaleza eran vistos como una eterna lucha de un orrenda contra otros. El papel de orenda se veía de manera similar a la tradición judeocristiana (así como islámica) en la que el espíritu Santo era la fuente y la fuerza para la profecía, la adivinación, los milagros, las bendiciones, la oración y la adoración.

Los T'boli tenían puntos de vista similares. "Fu, el espíritu de la tierra, tiene un carácter dual. A veces es benevolente, que Fu ayudaría a las personas, especialmente a los agricultores, bendiciéndolos con cosechas abundantes o curando al miembro enfermo de una familia; en otras ocasiones, malévolo, que Fu causa enfermedades y destruye las cosechas. La comprensión de la dualidad de las características del espíritu otorga a cada T'boli una reverencia por el entorno que se extiende a los diferentes elementos que comulgan con él. De hecho, los árboles, los animales y el agua no se consideran meros elementos sino otras entidades espirituales [vivientes].
II Paradigma Cuerpo-Mente-Espíritu - ¡Símbolos espirituales inconscientes cargados de emociones genéticas!: Tribus nativas americanas, Ho'omana hawaianas, + tribus indígenas filipinas Orden social Ifugao (R Reyes) Creencias T'boli + Kapwa filipino
Creators: name: Peck Jr, Charles
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Indigenous peoples
subject: Hispanic Americans
subject: Latin poetry
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Ethics
subject: Philosophy, Spanish
subject: Spanish poetry
subject: Hispanic American women
subject: Hispanic Americans--Ethnic identity
subject: Art, South American

description: Entre las culturas nativas americanas, parece haber habido una aceptación casi universal del concepto de “espíritu-fuerza vital” intrínseco al mundo, la naturaleza y las personas, omnipresente en la cultura nativa americana. Por ejemplo, los sioux adoptaron el concepto de wakd o mahopa; el Algonquin, la idea de manitowi; los Mahopa Shoshone usaron la palabra pukunt. Entre las tribus iroquesas, los mohawk, cayuga y oneida se referían al concepto como orenna o karenna, urente por los tuscarora y iarenda u orenda por los hurones. Orenda (u orenna) es un nombre iroqués para un poder espiritual intrínseco a las personas y al mundo. El mundo y la naturaleza eran vistos como una eterna lucha de un orrenda contra otros. El papel de orenda se veía de manera similar a la tradición judeocristiana (así como islámica) en la que el espíritu Santo era la fuente y la fuerza para la profecía, la adivinación, los milagros, las bendiciones, la oración y la adoración.  Los T'boli tenían puntos de vista similares. “Fu, el espíritu de la tierra, tiene un carácter dual. A veces es benevolente, que Fu ayudaría a las personas, especialmente a los agricultores, bendiciéndolos con cosechas abundantes o curando al miembro enfermo de una familia; en otras ocasiones, malévolo, que Fu causa enfermedades y destruye las cosechas. La comprensión de la dualidad de las características del espíritu otorga a cada T'boli una reverencia por el entorno que se extiende a los diferentes elementos que comulgan con él. De hecho, los árboles, los animales y el agua no se consideran meros elementos sino otras entidades espirituales [vivientes].
The satellite galaxy plane of NGC 4490 in light of ΛCDM - Sparsity of similarly extreme analogs and a possible role of satellite pairs
Creators: name: Pawlowski, Marcel S.
name: Müller, Oliver
name: Taibi, Salvatore
name: Júlio, Mariana P.
name: Kanehisa, Kosuke Jamie
name: Heesters, Nick
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The galaxy system around NGC4490 was recently highlighted to display a flattened, kinematically correlated structure reminiscent of satellite galaxy planes around other hosts. Since known satellite planes are in tension with $Λ$CDM expectations from cosmological simulations, we quantitatively assess for the first time the tension posed by the NGC4490 system. We measure the on-sky flattening as the major-to-minor axis ratio b/a of the satellite distribution and their line-of-sight kinematic correlation. Analogs are selected in the IllustrisTNG-50 simulation and their flattening and correlation are similarly measured. We confirm the strong kinematic coherence of all 12 observed objects with available line-of-sight velocities (of 14 in total): the northern ones approach and the southern ones recede relative to the host. The spatial distribution of all 14 objects is substantially flattened with b/a=0.38 (0.26 considering only the 12 objects with velocities). Such extreme arrangements are rare in the simulation at 0.21-0.35%. This would drop further if at least one of the two satellite objects without velocities is confirmed to follow the kinematic trend, and would become zero if both are rejected as non-members. We also identify a likely galaxy pair in the observed system, and find a similar pair in the best-matching simulated analog. Our findings establish NGC4490 as another strong example of a satellite plane in the Local Volume. This emphasizes that planes of satellites are a more general issue faced by $Λ$CDM also beyond the Local Group. The tension with typical systems in simulations suggests that the observed one requires a specific formation scenario, potentially connected to the larger-scale galaxy alignment in its vicinity. The presence of galaxy pairs in the observed and a simulated system hints at the importance such groupings may have to understand satellite planes.
description: 9 pages, 6 figures, 1 satellite galaxy plane. Accepted for publication in A&A. Abstract slightly abridged
sj-docx-1-cnr-10.1177_10547738211027223 – Supplemental material for Men’s Perceptions of Violence against Women: Improving Cultural Literacy for Combating Violence within Family
Creators: name: Al-Natour, Ahlam
name: Gillespie, Gordon Lee
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-cnr-10.1177_10547738211027223 for Men’s Perceptions of Violence against Women: Improving Cultural Literacy for Combating Violence within Family by Ahlam Al-Natour and Gordon Lee Gillespie in Clinical Nursing Research
Domain walls in super Yang-Mills: worldvolume TQFTs and deconfinement from semiclassics on $\mathbb{R}^3\times\mathbb{S}^1$
Creators: name: Cox, Andrew A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: This work studies domain walls between chirally-separated vacua in supersymmetric Yang-Mills theory (SYM) on $\mathbb{R}^3\times\mathbb{S}^1$ in the semiclassical limit. For all gauge groups we explicitly find the electric fluxes of all BPS domain walls and fully characterize the representation that they form under the global symmetry of SYM. We compute the characters of these representations formed by the semiclassical domain walls. We also compute these characters for the worldvolume TQFTs appearing in the literature for $SU(N)$ and $Sp(N)$ gauge groups. We find complete agreement between the two computations, providing thus a dynamical test of the proposed worldvolume TQFTs. We also propose a new worldvolume TQFT for $E_6$ domain walls, subjecting it to the same tests. Finally, we study deconfinement of quarks on domain walls for all gauge groups. We show that for all gauge groups confining strings (stable in the abelianized regime) can end on domain walls, regardless of whether or not the group has a center.
description: 57 pages, 8 figures
sj-pdf-1-sro-10.1177_13607804211019760 – Supplemental material for Beyond a Dichotomous Understanding of Online Anonymity: Bridging the Macro and Micro Level
Creators: name: Eklund, Lina
name: von Essen, Emma
name: Jonsson, Fatima
name: Johansson, Magnus
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-sro-10.1177_13607804211019760 for Beyond a Dichotomous Understanding of Online Anonymity: Bridging the Macro and Micro Level by Lina Eklund, Emma von Essen, Fatima Jonsson and Magnus Johansson in Sociological Research Online
HERV-K(HML-2), the best preserved family of HERVs: endogenization, expression, and implications in health and disease
Creators: name: Hohn, Oliver
name: Hanke, Kirsten
name: Bannert, Norbert
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2013
Subjects: subject: human endogenous retrovirus
subject: HERV-K
subject: replication
subject: Rec
subject: cancer
subject: 610 Medizin

description: Retroviruses that have the ability to infect germ line cells can become an integral and inherited part of the host genome. About 8% of the human chromosomal DNA consists of sequences derived from infections by retroviruses that presumably circulated 2–40 millions of years ago, and some elements are actually much older. Post-insertional recombinations, deletions, and mutations have rendered all known human endogenous retroviruses (HERVs) non-infectious. However some, particularly the most recently acquired proviruses of the HERV-K(HML-2) family, can expresses viral proteins and produce viral particles. In this review we will first discuss the major aspects of the endogenization process and peculiarities of the different HERV-K families. We will then focus on the genes and proteins encoded by HERV-K(HML-2) as well as inactivation of these proviruses by postinsertional mutations and their inhibition by antiretroviral factors. After describing the evolutionary interplay between host and endogenous retrovirus we will delve deeper into the currently limited understanding of HERV-K and its possible association with disease, particularly tumorigenesis.
Additional file 1 of The association of regional block with intraoperative opioid consumption in patients undergoing video-assisted thoracoscopic surgery: a single-center, retrospective study
Creators: name: Xiang, Yan
name: Chen, Liang
name: Jia, Jiang
name: Yili, Fu
name: Changwei, Wei
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Supplementary Material 1
title: Rapid Prototyping Augmented Skin Pathology for Medical Simulation and Training
Creators: name: Castelino, Annette
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2009

description: The goal of this research is to study how augmented reality technology could be applied in training medical students for better clinical practice and diagnosis in the treatment of skin conditions using skin pathology prototypes. Described within this thesis is an innovative method of producing skin abscess prototypes that augment the Standardized Patient (SP) for simulation purposes.

The method adopted is a combination of the cost-effective technique of rapid prototyping (RP) — 3D inkjet printing and 3D graphics modeling. The visual and haptic realism of these developed prototypes along with the use of moulage enable the SP to exhibit realistic skin boils and lesions. Results of visual and haptic realism with the developed prototype were evaluated by expert feedback from a physician educator at Eastern Virginia Medical School. Moreover, the prototypes were assessed for their safety standards by the estimation of approximate cutting-force. Therefore, the skin abscess prototypes developed are visually and haptically real, cost-effective and safe to use on SPs thereby serving as an educational and patient information tool in the treatment of skin pathology.
Koala retroviruses: characterization and impact on the life of koalas
Creators: name: Denner, Joachim
name: Young, Paul R.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2013
Subjects: subject: Lymphoma
subject: Gammaretroviruses
subject: Koala retrovirus
subject: Immunodeficiency
subject: 610 Medizin

description: Koala retroviruses (KoRV) have been isolated from wild and captive koalas in Australia as well as from koala populations held in zoos in other countries. They are members of the genus Gammaretrovirus, are most closely related to gibbon ape leukemia virus (GaLV), feline leukemia virus (FeLV) and porcine endogenous retrovirus (PERV) and are likely the result of a relatively recent trans-species transmission from rodents or bats. The first KoRV to be isolated, KoRV-A, is widely distributed in the koala population in both integrated endogenous and infectious exogenous forms with evidence from museum specimens older than 150 years, indicating a relatively long engagement with the koala population. More recently, additional subtypes of KoRV that are not endogenized have been identified based on sequence differences and host cell receptor specificity (KoRV-B and KoRV-J). A specific association with fatal lymphoma and leukemia has been recently suggested for KoRV-B. In addition, it has been proposed that the high viral loads found in many animals may lead to immunomodulation resulting in a higher incidence of diseases such as chlamydiosis. Although the molecular basis of this immunomodulation is still unclear, purified KoRV particles and a peptide corresponding to a highly conserved domain in the envelope protein have been shown to modulate cytokine expression in vitro, similar to that induced by other gammaretroviruses. While much is still to be learned, KoRV induced lymphoma/leukemia and opportunistic disease arising as a consequence of immunomodulation are likely to play an important role in the stability of koala populations both in the wild and in captivity.
An In-Depth Analysis of Cybersecurity Frameworks for Payment Applications
Creators: name: Mooghala, Sridhar
name: Mooghala, Sridhar
Publisher: name: Humanities Commons
Year: 2021

description: Purpose: The essay looks at the most important problem of digital payments by considering a broad range of cybersecurity frameworks used in payment applications. By analyzing the multiple challenges posed by digital settlement, the purpose is accomplished while also elucidating the crucial role that strong cybersecurity plays in mining them. Method: The research is based on a literature review of existing literature, qualitative case studies, and an analysis of actual cybersecurity in digital payments. Through a synthesis of different information sources, construction of the complexity existing in securing digital payments through a variety of cybersecurity architecture and technologies is a necessity. Findings: The research establishes major digital payments’ security concerns such as identity theft, personal info leaks, and frauds, then it evaluates top cybersecurity techniques, like digital signature, tokenization, multi - factor authentication and vital requirements of regulatory bodies’ compliance, taking an example of two highly successive digital payment and electronic payments Pursuits - Apple Pay and Google Pay project. Unique Contribution to Theory, Practice, and Policy: It contributes to existing research scholarship by synthesizing insights into a single narrative that articulates meta - concept to mean a practice that combines popular cases and evidenced frameworks into a practical road map for stakeholders of the payment ecosystem. Secondly, it contributes to policy discourse by taking a call - to - action stance on collaborative approaches, user education, and ethics in digital payment security.
Occupation and educational inequalities in laryngeal cancer: the use of a job index
Creators: name: Santi, Irene
name: Kroll, Lars Eric
name: Dietz, Andreas
name: Becher, Heiko
name: Ramroth, Heribert
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2013
Subjects: subject: Education
subject: Laryngeal cancer
subject: Occupational indices
subject: Exposure substance check list
subject: 610 Medizin

description: Background: Previous studies tried to assess the association between socioeconomic status and laryngeal cancer. Alcohol and tobacco consumption explain already a large part of the social inequalities. Occupational exposures might explain a part of the remaining but the components and pathways of the socioeconomic contribution have yet to be fully disentangled. The aim of this study was to evaluate the role of occupation using different occupational indices, differentiating between physical, psycho-social and toxic exposures and trying to summarize the occupational burden into one variable. Methods: A population-based case–control study conducted in Germany in 1998–2000 included 208 male cases and 702 controls. Information on occupational history, smoking, alcohol consumption and education was collected with face-to-face interviews. A recently developed job-classification index was used to account for the occupational burden. A sub-index focussed on jobs involving potentially carcinogenic agents (CAI) for the upper aero digestive tract. Results: When adjusted for smoking and alcohol consumption, higher odds ratios (ORs) were found for lower education. This OR decreased after further adjustment using the physical and psycho-social job indices (OR = 3.2, 95%-CI: 1.5-6.8), similar to the OR using the sub-index CAI (OR = 3.0, 95%-CI: 1.4-6.5). Conclusions: The use of an easily applicable control variable, simply constructed on standard occupational job classifications, provides the possibility to differentiate between educational and occupational contributions. Such an index might indirectly reflect the effect of carcinogenic agents, which are not collected in many studies.
Direct RNA-Based Detection and Differentiation of CTX-M-Type Extended-Spectrum β-Lactamases (ESBL)
Creators: name: Stein, Claudia
name: Makarewicz, Oliwia
name: Pfeifer, Yvonne
name: Brandt, Christian
name: Ramos, João Costa
name: Klinger, Mareike
name: Pletz, Mathias W.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2013
Subjects: subject: beta-Lactamases/genetics
subject: Real-Time Polymerase Chain Reaction
subject: Mutation
subject: Escherichia coli/enzymology
subject: RNA/genetics
subject: Reverse Transcription
subject: 610 Medizin

description: The current global spread of multi-resistant Gram-negatives, particularly extended spectrum β-lactamases expressing bacteria, increases the likelihood of inappropriate empiric treatment of critically ill patients with subsequently increased mortality. From a clinical perspective, fast detection of resistant pathogens would allow a pre-emptive correction of an initially inappropriate treatment. Here we present diagnostic amplification-sequencing approach as proof of principal based on the fast molecular detection and correct discrimination of CTX-M-β-lactamases, the most frequent ESBL family. The workflow consists of the isolation of total mRNA and CTX-M-specific reverse transcription (RT), amplification and pyrosequencing. Due to the high variability of the CTX-M-β-lactamase-genes, degenerated primers for RT, qRT as well as for pyrosequencing, were used and the suitability and discriminatory performance of two conserved positions within the CTX-M genes were analyzed, using one protocol for all isolates and positions, respectively. Using this approach, no information regarding the expected CTX-M variant is needed since all sequences are covered by these degenerated primers. The presented workflow can be conducted within eight hours and has the potential to be expanded to other β-lactamase families.
THE EVOLVING JAVA ECOSYSTEM AND ITS UNIQUE APPLICABILITY IN FINANCIAL TECHNOLOGIES
Creators: name: Mooghala, Sridhar
name: Mooghala, Sridhar
Publisher: name: Humanities Commons
Year: 2023

description: The Java programming language, developed in the middle of the 1990s under the direction of Sun Microsystems, has repeatedly proven its durability and importance over almost three decades. With its ground-breaking "write once, run anywhere" attitude, which encouraged platform-independent application development and significantly reduced costs, the software industry underwent a revolution. The Java Virtual Machine (JVM), which enables smooth execution across several operating systems, is the foundation of its enduring success. As it forayed into cloud computing, Big Data, and the Internet of Things (IoT), Java's versatility became clear. Adaptability, scalability, and dependability define its function in cloud-native applications. Java's usefulness in IoT applications for effective data management in finance and its ability to handle large datasets utilizing frameworks like Apache, Hadoop, and Spark underlines its importance. The personalized subscription strategy used by Oracle increases Java's usefulness in the financial industry. Thanks to its versatility, rich library support, and vibrant developer community, Java is well-positioned for cutting-edge financial technologies like quantum computing, edge computing, and AI. Its open-source design ensures its longevity and solidifies its position as a foundational technology for safe, scalable solutions that foster creativity in the rapidly changing financial technology landscape.
sj-pdf-1-vdi-10.1177_10406387211027221 – Supplemental material for PRRSV2 genetic diversity defined by RFLP patterns in the United States from 2007 to 2019
Creators: name: Trevisan, Giovani
name: Sharma, Aditi
name: Gauger, Phillip
name: Harmon, Karen M.
name: Zhang, Jianqiang
name: Main, Rodger
name: Zeller, Michael
name: Linhares, Leticia C. M.
name: Linhares, Daniel C. L.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-pdf-1-vdi-10.1177_10406387211027221 for PRRSV2 genetic diversity defined by RFLP patterns in the United States from 2007 to 2019 by Giovani Trevisan, Aditi Sharma, Phillip Gauger, Karen M. Harmon, Jianqiang Zhang, Rodger Main, Michael Zeller, Leticia C. M. Linhares and Daniel C. L. Linhares in Journal of Veterinary Diagnostic Investigation
Additional file 2 of The association of regional block with intraoperative opioid consumption in patients undergoing video-assisted thoracoscopic surgery: a single-center, retrospective study
Creators: name: Xiang, Yan
name: Chen, Liang
name: Jia, Jiang
name: Yili, Fu
name: Changwei, Wei
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Supplementary Material 2
II La necesidad de significado - Drive to Understand con una nueva introducción a la investigación inconsciente "El placer más noble es la alegría de comprender". - Leonardo da Vinci - William James, Clifford Geertz, Roy Rappaport Albert Einstein, Tolstoy
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2024
Subjects: subject: Faith
subject: Hispanic Americans
subject: Universidad de Buenos Aires. Facultad de Filosofía y Letras
subject: Indigenous peoples--Social conditions
subject: Indigenous peoples
subject: Art, Latin American
subject: Social cognitive theory
subject: Spanish American literature--Philosophy
subject: Universidad Nacional Autónoma de México. Facultad de Filosofía y Letras
subject: Philosophy, Spanish

description: El número de suicidios en los EE. UU. en 2022 alcanza un nivel récord: CDC Se estima que 49,449 personas murieron por suicidio en 2022, la historia de la psicología de Tull no tenía referencias a la emanación, los estudiantes estadounidenses con los que hablé ni habían oído hablar de una "necesidad de significado" Como Dherif y Frankl señalan que las escuelas de pensamiento están separadas y desconectadas. El Dr. Paul Wong editó las antologías: dos ediciones de The Human Quest for Meaning: A Handbook of Psychoological Research and Clinical Applications (1998) y The Human Quest for Meaning: Theories, Research, and Applications (2012), repletas de estudios y análisis de significado.
. En su libro, El hombre en busca de sentido, Frankl señala que cuando la vida dejó de tener sentido para las personas, dejaron de luchar por vivir. Observó que las creencias religiosas de los presos eran intensas y muy sinceras. Una mujer que sabía que moriría en los próximos días le dijo: "Estoy agradecida de que el destino me haya golpeado tan fuerte. En mi vida anterior estaba mimado y no tomaba en serio los logros espirituales". (p.69) Además, afirma: "A pesar de toda la primitividad física y mental impuesta de la vida en un campo de concentración, fue posible que la vida espiritual se profundizara. Las personas sensibles que estaban acostumbradas a una rica vida intelectual pueden haber sufrido mucho dolor (a menudo eran de constitución delicada), pero el daño a su yo interior fue menor. Pudieron retirarse de su terrible entorno a una vida de riqueza interior y libertad espiritual. Sólo de esta manera se puede explicar la aparente paradoja de que algunos prisioneros de carácter menos resistente a menudo parecían sobrevivir a la vida en el campo mejor que aquellos de naturaleza robusta". (p. 37 búsqueda)
Additional file 3 of The association of regional block with intraoperative opioid consumption in patients undergoing video-assisted thoracoscopic surgery: a single-center, retrospective study
Creators: name: Xiang, Yan
name: Chen, Liang
name: Jia, Jiang
name: Yili, Fu
name: Changwei, Wei
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Supplementary Material 3
II La necesidad de significado - Drive to Understand con una nueva introducción a la investigación inconsciente "El placer más noble es la alegría de comprender". - Leonardo da Vinci - William James, Clifford Geertz, Roy Rappaport Albert Einstein, Tolstoy
Creators: name: Peck Jr, Charles
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Indigenous peoples
subject: Indigenous peoples--Social conditions
subject: Hispanic Americans
subject: Universidad Nacional Autónoma de México. Facultad de Filosofía y Letras
subject: Universidad de Buenos Aires. Facultad de Filosofía y Letras
subject: Philosophy, Spanish
subject: Art, Latin American
subject: Spanish American literature--Philosophy
subject: Social cognitive theory
subject: Faith

description: El número de suicidios en los EE. UU. en 2022 alcanza un nivel récord: CDC Se estima que 49,449 personas murieron por suicidio en 2022, la historia de la psicología de Tull no tenía referencias a la emanación, los estudiantes estadounidenses con los que hablé ni habían oído hablar de una "necesidad de significado" Como Dherif y Frankl señalan que las escuelas de pensamiento están separadas y desconectadas. El Dr. Paul Wong editó las antologías: dos ediciones de The Human Quest for Meaning: A Handbook of Psychoological Research and Clinical Applications (1998) y The Human Quest for Meaning: Theories, Research, and Applications (2012), repletas de estudios y análisis de significado. . En su libro, El hombre en busca de sentido, Frankl señala que cuando la vida dejó de tener sentido para las personas, dejaron de luchar por vivir. Observó que las creencias religiosas de los presos eran intensas y muy sinceras. Una mujer que sabía que moriría en los próximos días le dijo: “Estoy agradecida de que el destino me haya golpeado tan fuerte. En mi vida anterior estaba mimado y no tomaba en serio los logros espirituales”. (p.69) Además, afirma: “A pesar de toda la primitividad física y mental impuesta de la vida en un campo de concentración, fue posible que la vida espiritual se profundizara. Las personas sensibles que estaban acostumbradas a una rica vida intelectual pueden haber sufrido mucho dolor (a menudo eran de constitución delicada), pero el daño a su yo interior fue menor. Pudieron retirarse de su terrible entorno a una vida de riqueza interior y libertad espiritual. Sólo de esta manera se puede explicar la aparente paradoja de que algunos prisioneros de carácter menos resistente a menudo parecían sobrevivir a la vida en el campo mejor que aquellos de naturaleza robusta”. (p. 37 búsqueda)
The Role of Topological Photon Spheres in Constraining the Parameters of Black Holes
Creators: name: Sadeghi, Jafar
name: Afshar, Mohammad Ali S.
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we investigate the topological photon sphere from two distinct perspectives. In the first view, we examine the existence and characteristics of topological photon(anti-photon)spheres for black holes with different structures, such as Einstein-Young-Mills non-minimal, AdS black holes surrounded by Chaplygin-like dark fluid, and Bardeen-like black holes in Einstein-Gauss-Bonnet gravity. Furthermore, we delve into the deeper perspective of the necessity of photon spheres for super-compact gravitational structures such as black holes. By leveraging this necessity, we propose a classification of the parameter space of black hole models based on the existence and positioning of photon spheres. This approach enables the determination of parameter ranges that delineate whether a solution represents a black hole or a naked singularity. In essence, the paper illustrates the utility of the photon sphere as a notable test for establishing the permissible and non-permissible parameter ranges within specific theories of black hole solutions.
description: 26 pages, 7 figures
sj-docx-1-tam-10.1177_17588359211027836 – Supplemental material for NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer
Creators: name: Yuan, Yuan
name: Gao, Huanyao
name: Zhuang, Yongxian
name: Wei, Lixuan
name: Yu, Jia
name: Zhang, Zhe
name: Zhang, Lili
name: Wang, Liewei
Publisher: name: SAGE Journals
Year: 2021
Subjects: Oncology and Carcinogenesis not elsewhere classified
Aged Health Care
Pharmacology and Pharmaceutical Sciences not elsewhere classified
Respiratory Diseases

description: Supplemental material, sj-docx-1-tam-10.1177_17588359211027836 for NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer by Yuan Yuan, Huanyao Gao, Yongxian Zhuang, Lixuan Wei, Jia Yu, Zhe Zhang, Lili Zhang and Liewei Wang in Therapeutic Advances in Medical Oncology
Ang pangangailangan para sa kahulugan - magmaneho sa understand w/ bagong walang kamalay-malay na pananaliksik intro "Ang pinakamarangal na kasiyahan ay ang kagalakan ng pag-unawa" - Leonardo Da Vinci, William James, C Geertz, Roy Rappaport  Einstein, +Mg
Creators: name: Peck Jr, Charles
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: University of the Philippines. College of Social Science and Philosophy
subject: Philosophy, Philippine
subject: Tiruray (Philippine people)--Psychology
subject: Ilongot (Philippine people)--Psychology
subject: Psychology
subject: FOS: Psychology
subject: Faith
subject: Meaning (Philosophy)
subject: Meaning (Psychology)
subject: Philippine Association of Colleges and Universities
subject: Filipinos

description: Ang bilang ng mga pagpapatiwakal sa US noong 2022 ay umabot na sa antas ng rekord: CDC Tinatayang 49,449 katao ang namatay sa pamamagitan ng pagpapakamatay noong 2022, ang kasaysayan ni Tull ng psycholgoy ay walang mga sanggunian sa emaning, mga estudyanteng Amerikano na kausap ko ay hindi rin nakarinig ng "pangangailangan para sa kahulugan" Bilang Dherif at itinuro ni Frankl na ang mga schcols ng pag-iisip ay hiwalay at hindi nakakonekta. Sa kaibahan sa mainstream psychology, existential psycholgoy - batay sa antas ng kalooban ni Grnbakls sa menaing.may malawak na pananaliksik sa menaing. Pinagtibay ni Dr Paul wong ang mga antolohiya - dalawang edisyon ng The Human Quest for Meaning: A Handbook of Psychological Research and Clinical Applications (1998) at The Human Quest for Meaning: Theories, Research, and Applications (2012), na umaapaw sa mga stiuidies at pagsusuri ng ibig sabihin. Ang napakalalim at makapangyarihang personal na mga karanasan bilang biktima ng kampong piitan ay lubhang nakaapekto sa mga pananaw ni Frankl sa sangkatauhan at sa tao. Sa kanyang aklat, Man’s Search For Meaning, binanggit ni Frankl na nang ang buhay ay naging walang kabuluhan para sa mga tao, tumigil sila sa pakikibaka upang mabuhay. Napansin niya na ang mga relihiyosong paniniwala ng mga bilanggo ay matindi at napakatapat. Isang babaeng alam na mamamatay siya sa susunod na mga araw ang nagsabi sa kanya, “Nagpapasalamat ako na sinaktan ako ng tadhana. Sa aking dating buhay ay naging spoiled ako at hindi sineseryoso ang espirituwal na mga nagawa.” (p.69) Dagdag pa, sinabi niya, “Sa kabila ng lahat ng ipinatupad na pisikal at mental na primitiveness ng buhay sa isang kampong piitan, posible para sa espirituwal na buhay na lumalim.
Ang pangangailangan para sa kahulugan - magmaneho sa understand w/ bagong walang kamalay-malay na pananaliksik intro "Ang pinakamarangal na kasiyahan ay ang kagalakan ng pag-unawa" - Leonardo Da Vinci, William James, C Geertz, Roy Rappaport Einstein, +Mg
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2024
Subjects: subject: Faith
subject: Meaning (Philosophy)
subject: Meaning (Psychology)
subject: University of the Philippines. College of Social Science and Philosophy
subject: Ilongot (Philippine people)--Psychology
subject: Philosophy, Philippine
subject: Psychology
subject: FOS: Psychology
subject: Tiruray (Philippine people)--Psychology
subject: Philippine Association of Colleges and Universities
subject: Filipinos

description: Ang bilang ng mga pagpapatiwakal sa US noong 2022 ay umabot na sa antas ng rekord: CDC Tinatayang 49,449 katao ang namatay sa pamamagitan ng pagpapakamatay noong 2022, ang kasaysayan ni Tull ng psycholgoy ay walang mga sanggunian sa emaning, mga estudyanteng Amerikano na kausap ko ay hindi rin nakarinig ng "pangangailangan para sa kahulugan" Bilang Dherif at itinuro ni Frankl na ang mga schcols ng pag-iisip ay hiwalay at hindi nakakonekta. Sa kaibahan sa mainstream psychology, existential psycholgoy - batay sa antas ng kalooban ni Grnbakls sa menaing.may malawak na pananaliksik sa menaing. Pinagtibay ni Dr Paul wong ang mga antolohiya - dalawang edisyon ng The Human Quest for Meaning: A Handbook of Psychological Research and Clinical Applications (1998) at The Human Quest for Meaning: Theories, Research, and Applications (2012), na umaapaw sa mga stiuidies at pagsusuri ng ibig sabihin.
Ang napakalalim at makapangyarihang personal na mga karanasan bilang biktima ng kampong piitan ay lubhang nakaapekto sa mga pananaw ni Frankl sa sangkatauhan at sa tao. Sa kanyang aklat, Man's Search For Meaning, binanggit ni Frankl na nang ang buhay ay naging walang kabuluhan para sa mga tao, tumigil sila sa pakikibaka upang mabuhay. Napansin niya na ang mga relihiyosong paniniwala ng mga bilanggo ay matindi at napakatapat. Isang babaeng alam na mamamatay siya sa susunod na mga araw ang nagsabi sa kanya, "Nagpapasalamat ako na sinaktan ako ng tadhana. Sa aking dating buhay ay naging spoiled ako at hindi sineseryoso ang espirituwal na mga nagawa." (p.69) Dagdag pa, sinabi niya, "Sa kabila ng lahat ng ipinatupad na pisikal at mental na primitiveness ng buhay sa isang kampong piitan, posible para sa espirituwal na buhay na lumalim.
sj-pdf-2-tam-10.1177_17588359211027836 – Supplemental material for NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer
Creators: name: Yuan, Yuan
name: Gao, Huanyao
name: Zhuang, Yongxian
name: Wei, Lixuan
name: Yu, Jia
name: Zhang, Zhe
name: Zhang, Lili
name: Wang, Liewei
Publisher: name: SAGE Journals
Year: 2021
Subjects: Oncology and Carcinogenesis not elsewhere classified
Aged Health Care
Pharmacology and Pharmaceutical Sciences not elsewhere classified
Respiratory Diseases

description: Supplemental material, sj-pdf-2-tam-10.1177_17588359211027836 for NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer by Yuan Yuan, Huanyao Gao, Yongxian Zhuang, Lixuan Wei, Jia Yu, Zhe Zhang, Lili Zhang and Liewei Wang in Therapeutic Advances in Medical Oncology
Influence of Motivation and Availability of Resources on Teachers’ Job Satisfaction in Public Secondary Schools in Minna, Niger State
Creators: name: Oyekunle, Olaitan
name: Oyekunle, Olaitan
Publisher: name: Humanities Commons
Year: 2024

description: The study conducted among teachers in public secondary schools in Minna revealed several key findings regarding factors influencing their motivation and job satisfaction. Firstly, teachers strongly agreed on ten factors that contribute to their motivation and job satisfaction, including favorable service conditions, access to sick leave, prompt payment of salaries, study leave with pay, and extra pay for extra-curricular activities with mean value ranging 3.67 to 4.55. Secondly, material resources were identified as crucial for job satisfaction, with teachers strongly agreeing on seven out of eight items related to resource availability, such as fully equipped offices, textbooks, notebooks, stationery, and overhead projectors mean value ranging from 3.37 – 4.36. Thirdly, financial resources were found to significantly impact job satisfaction, with six out of seven items related to financial factors influencing stability and satisfaction among teachers. Additionally, teacher job performance was highlighted as a significant determinant of job satisfaction, with aspects like subject mastery, lesson preparation, and adherence to rules playing crucial roles. Importantly, there were no significant differences observed between male and female teachers in their perceptions of motivation, material resources, financial resources, and job performance, indicating a uniform perception across genders regarding factors influencing job satisfaction. The researcher recommendations that the State government should reconsider the service condition and make it favourable, implement prompt payment of salaries as at when due, thereby reconsidering the policies and amending them to fit in with the required need of the teachers and more recent trend and demand of the nation.
Cataloging and Metadata Town Hall (2024)
Creators: name: Belford, Rebecca
name: D'Ver, Ethan
name: Kishimoto, Kevin
name: Knop, Keith
name: Martin, Leonard
name: Mullin, Casey
name: Scharff, Mark
name: West, Janelle
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Cataloging of music
subject: NACO (Program)
subject: Subject headings
subject: MARC formats
subject: Resource description & access

description: This session features updates and special topics in music cataloging and metadata; it is a forum for sharing information on important topics that do not each require their own program sessions. Speakers will provide up to date information on changes to RDA (as well as LC-PCC Policy Statements and MLA Best Practices), LCGFT, LCMPT, LCDGT, MARC, LDWG (MLA’s Linked Data Working Group), and the music PCC funnels. Special focus this year will be on the NACO-Music Project (NMP) and RDA.