cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A
Creators: name: Steward, Charles A.
name: Roovers, Jolien
name: Suner, Marie-Marthe
name: Gonzalez, Jose M.
name: Uszczynska-Ratajczak, Barbara
name: Pervouchine, Dmitri
name: Fitzgerald, Stephen
name: Viola, Margarida
name: Stamberger, Hannah
name: Hamdan, Fadi F.
name: Ceulemans, Berten
name: Leroy, Patricia
name: Nava, Caroline
name: Lepine, Anne
name: Tapanari, Electra
name: Keiller, Don
name: Abbs, Stephen
name: Sanchis-Juan, Alba
name: Grozeva, Detelina
name: Rogers, Anthony S.
name: Diekhans, Mark
name: Guigó, Roderic
name: Petryszak, Robert
name: Minassian, Berge A.
name: Cavalleri, Gianpiero
name: Vitsios, Dimitrios
name: Petrovski, Slavé
name: Harrow, Jennifer
name: Flicek, Paul
name: Lucy Raymond, F.
name: Lench, Nicholas J.
name: Jonghe, Peter De
name: Mudge, Jonathan M.
name: Weckhuysen, Sarah
name: Sisodiya, Sanjay M.
name: Frankish, Adam
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
/692/4017
/631/61/212/2301
article

description: Funder: Agency for Innovation by Science and Technology, IWT
description: Funder: U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (NHGRI)
description: Funder: BOF-University of Antwerp (FFB180053) and FWO (1861419N).
description: Abstract: The developmental and epileptic encephalopathies (DEE) are a group of rare, severe neurodevelopmental disorders, where even the most thorough sequencing studies leave 60–65% of patients without a molecular diagnosis. Here, we explore the incompleteness of transcript models used for exome and genome analysis as one potential explanation for a lack of current diagnoses. Therefore, we have updated the GENCODE gene annotation for 191 epilepsy-associated genes, using human brain-derived transcriptomic libraries and other data to build 3,550 putative transcript models. Our annotations increase the transcriptional ‘footprint’ of these genes by over 674 kb. Using SCN1A as a case study, due to its close phenotype/genotype correlation with Dravet syndrome, we screened 122 people with Dravet syndrome or a similar phenotype with a panel of exon sequences representing eight established genes and identified two de novo SCN1A variants that now - through improved gene annotation - are ascribed to residing among our exons. These two (from 122 screened people, 1.6%) molecular diagnoses carry significant clinical implications. Furthermore, we identified a previously classified SCN1A intronic Dravet syndrome-associated variant that now lies within a deeply conserved exon. Our findings illustrate the potential gains of thorough gene annotation in improving diagnostic yields for genetic disorders.
Nucleon-Nucleon Coincidence Spectra in the Non-Mesonic Weak Decay of Lambda-Hypernuclei and the n/p Puzzle
Creators: name: Garbarino, G.
name: Parreno, A.
name: Ramos, A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The main open problem in the physics of Lambda-hypernuclei is the lack of a sound theoretical interpretation of the large experimental values for the ratio G_n/G_p. To approach the problem, we have incorporated a Lambda N-> nN one-meson-exchange model in an intranuclear cascade code for a finite nucleus calculation of the nucleon-nucleon (angular and energy) coincidence distributions in the non-mesonic weak decay of 5_Lambda-He and 12_Lambda-C hypernuclei. The two-nucleon induced decay mechanism, Lambda np-> nnp, has been taken into account by means of the polarization propagator formalism in local density approximation. With respect to single nucleon spectra studies, the treatment of two-nucleon correlations allow a cleaner and more direct determination, from data, of G_n/G_p. Our results agree with the preliminary coincidence data of KEK-E462 for 5_Lambda-He. This allows us to conclude that G_n/G_p for 5_Lambda-He should be close to 0.46, the value predicted by our one-meson-exchange model for this hypernucleus. Unfortunately, to disentangle one- and two-body induced decay channels from experimental non-mesonic decay events, three-nucleon coincidences should be measured.
description: 4 RevTeX pages, 5 figures; a small error in calculations has been corrected and Figs. 1, 2, 4 and Tab. II changed accordingly; minor rephrasing
title: The Political Culture of Kenya vol.2
Creators: name: Berg-Schlosser, Dirk
Publisher: name: Philipps-Universität Marburg
Year: 1978
Subjects: subject: Political science
subject: FOS: Political science
subject: Politik

description: Elektronische Reproduktion von: The political culture of Kenya : a comparative analysis of its main ethnic components and their interactions at the national level / von Dirk Berg-Schlosser. - Halbbd. 2. - S. 405 - 772 : graph. Darst., Kt. -
Bemerkungen: Augsburg, Univ., Habil.-Schr., 1978. - 

Digitalisiert 2024
Human Cognitive Neuroscience as It Is Taught
Creators: name: Hauk, Olaf
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: subject: Psychology
subject: FOS: Psychology
subject: neuroimaging
subject: training
subject: skills
subject: survey
subject: fMRI
subject: EEG
subject: MEG
subject: computational modeling

description: Cognitive neuroscience increasingly relies on complex data analysis methods. Researchers in this field come from highly diverse scientific backgrounds, such as psychology, engineering, and medicine. This poses challenges with respect to acquisition of appropriate scientific computing and data analysis skills, as well as communication among researchers with different knowledge and skills sets. Are researchers in cognitive neuroscience adequately equipped to address these challenges? Here, we present evidence from an online survey of methods skills. Respondents (n = 307) mainly comprised students and post-doctoral researchers working in the cognitive neurosciences. Multiple choice questions addressed a variety of basic and fundamental aspects of neuroimaging data analysis, such as signal analysis, linear algebra, and statistics. We analyzed performance with respect to the following factors: undergraduate degree (grouped into Psychology, Methods, and Biology), current researcher status (undergraduate student, PhD student, and post-doctoral researcher), gender, and self-rated expertise levels. Overall accuracy was 72%. Not surprisingly, the Methods group performed best (87%), followed by Biology (73%) and Psychology (66%). Accuracy increased from undergraduate (59%) to PhD (74%) level, but not from PhD to post-doctoral (74%) level. The difference in performance for the Methods vs. non-methods (Psychology/Biology) groups was especially striking for questions related to signal analysis and linear algebra, two areas particularly relevant to neuroimaging research. Self-rated methods expertise was not strongly predictive of performance. The majority of respondents (93%) indicated they would like to receive at least some additional training on the topics covered in this survey. In conclusion, methods skills among junior researchers in cognitive neuroscience can be improved, researchers are aware of this, and there is strong demand for more skills-oriented training opportunities. We hope that this survey will provide an empirical basis for the development of bespoke skills-oriented training programs in cognitive neuroscience institutions. We will provide practical suggestions on how to achieve this.
Additional file 6: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets
Creators: name: Perconti, Giovanni
name: Rubino, Patrizia
name: Contino, Flavia
name: Bivona, Serena
name: Bertolazzi, Giorgio
name: Tumminello, Michele
name: Feo, Salvatore
name: Giallongo, Agata
name: Coronnello, Claudia
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology
subject: Computational Biology

description: Wilcoxon test p-values summary. Wilcoxon test p-values (log10) obtained by comparing the variable values associated with the enriched/underrepresented genes sets. Three different miRNA target prediction tools (Targetscan, PITA and miRanda) were used to compute the necessary binding sites (BS) matrices. The BS matrices used to compute the p-values in the last panel were obtained by considering BS predicted by at least two of the three prediction tools. In each panel, the variables computed with the three AGO2 IN profiles were used to distinguish enriched and underrepresented genes in AGO2-IP vs FT and the variables computed with the three GW182 IN profiles were used to distinguish enriched and underrepresented genes in GW182-IP vs FT. (PDF 133 kb)
Mapping class groups of highly connected ( 4 k + 2 ) -manifolds
Creators: name: Krannich, Manuel
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
57R50
55N22
57R60

description: Funder: University of Cambridge
description: Abstract: We compute the mapping class group of the manifolds ♯g(S2k+1×S2k+1) for k>0 in terms of the automorphism group of the middle homology and the group of homotopy (4k+3)-spheres. We furthermore identify its Torelli subgroup, determine the abelianisations, and relate our results to the group of homotopy equivalences of these manifolds.
Constructions of k-uniform and absolutely maximally entangled states beyond maximum distance codes
Creators: name: Raissi, Zahra
name: Teixido, Adam
name: Gogolin, Christian
name: Acin, Antonio
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Pure multipartite quantum states of n parties and local dimension q are called k-uniform if all reductions to k parties are maximally mixed. These states are relevant for our understanding of multipartite entanglement, quantum information protocols, and the construction of quantum error correction codes. To our knowledge, the only known systematic construction of these quantum states is based on classical error correction codes. We present a systematic method to construct other examples of k-uniform states and show that the states derived through our construction are not equivalent to any k-uniform state constructed from the so-called maximum distance separable error correction codes. Furthermore, we use our method to construct several examples of absolutely maximally entangled states whose existence was open so far.
description: 5 pages, 2 figures, Comments are very welcome!
Pomatoceros triqueter
Creators: name: Ben-Eliahu, M. Nechama
name: Ten Hove, Harry A.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Polychaeta
Sabellida
Serpulidae
Pomatoceros
Pomatoceros triqueter

description: Pomatoceros triqueter (Linnaeus, 1758)
 Type locality. Not precisely known, but North Atlantic. Not present in the Suez Canal, but see Spirobranchus tetraceros, below. On ecological grounds, it is inconceivable that Pomatoceros triqueter has replaced Spirobranchus tetraceros in the intertidal and splash zone around Alexandria, Egypt as recently reported by El-Rashidy et al. (2009), a finding that contradicts Abd-Elnaby (2005) [quoted by Ghobashy & Ghobashy (2005: 90–93); see Spirobranchus tetraceros, below]).
description: Published as part of Ben-Eliahu, M. Nechama & Ten Hove, Harry A., 2011, Serpulidae (Annelida: Polychaeta) from the Suez Canal- From a Lessepsian Migration Perspective (a Monograph) 2848, pp. 1-147 in Zootaxa 2848 (1) on page 43, DOI: 10.11646/zootaxa.2848.1.1, http://zenodo.org/record/5287534
A Model for Granular Texture with Steric Exclusion
Creators: name: Troadec, H.
name: Radjai, F.
name: Roux, S.
name: Charmet, J. C.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We propose a new method to characterize the geometrical texture of a granular packing at the particle scale including the steric hindrance effect. This method is based on the assumption of a maximum disorder (entropy) compatible both with strain-induced anisotropy of the contact network and steric exclusions. We show that the predicted statistics for the local configurations is in a fairly agreement with our numerical data.
description: 9 pages, 5 figures
Additional file 4: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets
Creators: name: Perconti, Giovanni
name: Rubino, Patrizia
name: Contino, Flavia
name: Bivona, Serena
name: Bertolazzi, Giorgio
name: Tumminello, Michele
name: Feo, Salvatore
name: Giallongo, Agata
name: Coronnello, Claudia
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Overview of gene expression levels in IP and FT samples. Focus on the enriched genes in AGO2-IP and GW182-IP vs FT samples. The reported expression levels are computed as the average values of the three performed experimental replicates. (PDF 1423 kb)
An information-theoretic Central Limit Theorem for finitely susceptible FKG systems
Creators: name: Johnson, Oliver
Publisher: name: arXiv
Year: 2001
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60F05, 94A15

description: We adapt arguments concerning entropy-theoretic convergence from the independent case to the case of FKG random variables. FKG systems are chosen since their dependence structure is controlled through covariance alone, though in the sequel we use many of the same arguments for weakly dependent random variables. As in previous work of Barron and Johnson, we consider random variables perturbed by small normals, since the FKG property gives us control of the resulting densities. We need to impose a finite susceptibility condition -- that is, the covariance between one random variable and the sum of all the random variables should remain finite.
description: 17 pages
Data Management for Nanotechnology Risk Governance
Creators: name: Bakker, Martine
name: Drobne, Damjana
name: Jeliazkova, Nina
name: Antreas Afantitis
name: Willighagen, Egon
name: Lynch, Iseult
Publisher: name: Zenodo
Year: 2021
Subjects: risk governance
integrated datasets
data management

description: This poster represents the role, remit and activities of the Data Management Core Group which forms part of the NMBP-13 Cluster of three projects collaborating to establish a Risk Governance Framework and a Risk Governance Council. While NANORIGO is focused on defining concepts and user needs, in RiskGone and Gov4nano the emphasis is on operationalisation / implementation of nanosafety data and FAIR solutions. Together, the three projects cover the whole data management spectrum to enable the risk governance of nanomaterials and provide knowledge in a useful format for the Nanomaterials Risk Governance Council (NRGC) once established. The poster was presented at ENF21
Emergence of the Unconventional Type-II Nambu-Goldstone Modes with Topological Origin in Bose Superfluids
Creators: name: Pan, Jian-Song
name: Liu, W. Vincent
name: Liu, Xiong-Jun
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Nambu-Goldstone (NG) modes in a nonrelativistic system can be classified into two types from their characteristic features: being of either an odd (type I) or an even (type II) power energy-momentum dispersion. Conventionally, the type-II NG modes may universally arise from spontaneous breaking of noncommutative symmetry pairs. Here, we predict a novel type of quadratically dispersed NG modes that emerges in mixed $s$ and $p$ band Bose superfluids in an optical lattice and, unlike the conventional type-II NG modes, cannot be solely interpreted with the celebrated symmetry-based argument. Instead, we show that the existence of such modes has a profound connection to the topological transition on projective complex order-parameter space. The detection scheme is also proposed. Our Letter reveals a new universal mechanism for emergence of type-II NG modes, which bridges intrinsically the Landau symmetry-breaking and topological theories.
description: 5+9 pages, 4 figures
Autism and the right to education in the EU: policy mapping and scoping review of Nordic countries Denmark, Finland, and Sweden
Creators: name: Van Kessel, Robin
name: Walsh, Sebastian
name: Ruigrok, Amber N. V.
name: Holt, Rosemary
name: Yliherva, Anneli
name: Kärnä, Eija
name: Moilanen, Irma
name: Hjörne, Eva
name: Johansson, Shruti Taneja
name: Schendel, Diana
name: Pedersen, Lennart
name: Jørgensen, Meta
name: Brayne, Carol
name: Baron-Cohen, Simon
name: Roman-Urrestarazu, Andres
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Research

description: Abstract: Introduction: The universal right to education for people with disabilities has been highlighted by the Universal Declaration on Human Rights and the Convention on the Rights of Persons with Disabilities. In this paper, we mapped policies addressing the right to education and special education needs of autistic children in Denmark, Sweden, and Finland. Methods: A policy path analysis was carried out using a scoping review as an underlying framework for data gathering. Policy mapping was performed independently by both lead authors to increase reliability. Results and discussion: The values of the Universal Declaration of Human Rights and the Convention on the Rights of Persons with Disabilities have been closely translated into the respective education systems of the countries under study, offering special education needs services and support in mainstream education with the aim of including as many children into mainstream education as possible. Even though the education systems are comparable, the approaches between the countries under study are slightly different. Denmark and Sweden have passed several policies specifically geared towards special education needs, while Finland incorporates this more in general education policy. Conclusion: All countries under study have incorporated the values of the Universal Declaration of Human Rights and the Convention on the Rights of Persons with Disabilities in their respective education systems while emphasising the need to include as many children in the mainstream system as possible.
Convergence of the Gaussian Expansion Method in Dimensionally Reduced Yang-Mills Integrals
Creators: name: Nishimura, Jun
name: Okubo, Toshiyuki
name: Sugino, Fumihiko
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We advocate a method to improve systematically the self-consistent harmonic approximation (or the Gaussian approximation), which has been employed extensively in condensed matter physics and statistical mechanics. We demonstrate the {\em convergence} of the method in a model obtained from dimensional reduction of SU($N$) Yang-Mills theory in $D$ dimensions. Explicit calculations have been carried out up to the 7th order in the large-N limit, and we do observe a clear convergence to Monte Carlo results. For $D \gtrsim 10$ the convergence is already achieved at the 3rd order, which suggests that the method is particularly useful for studying the IIB matrix model, a conjectured nonperturbative definition of type IIB superstring theory.
description: LaTeX, 4 pages, 5 figures; title slightly changed, explanations added (16 pages, 14 figures), final version published in JHEP
MPEC 2024-C135 : 2024 CY2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 CY2

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Serpula vermicularis Linnaeus 1767
Creators: name: Ben-Eliahu, M. Nechama
name: Ten Hove, Harry A.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Agaricomycetes
Boletales
Serpulaceae
Serpula
Serpula vermicularis

description: Serpula vermicularis Linnaeus, 1767
Table 4
 Type locality. European Seas. Not present in the Suez Canal, but see Hydroides elegans, Hydroides spp., Serpula hartmanae and S. jukesii sections, above.
 Remarks. As discussed above, the taxon Serpula is difficult to classify. The record of S. vermicularis by Selim (2009: 73) from the Suez Canal is unlikely to belong to this boreal-temperate taxon. Given as a listing in a table only, not even with the number of opercular radii, presumably it should be attributed to an unidentified Hydroides species juvenile stage with a primary operculum, or possibly even to Serpula hartmanae. Without verification from direct examination of the specimen, it is presently only possible to regard this record from the northern canal as questionable.
 Comparative material examined. Atlantic: North Atlantic: Lervik, Stordoe, Hardanger Fjord, Norway, 183–238 m, VI.1892, det. S.F. Harmer Serpula vermicularis, CUZM, 5 specs. Largest, length 58 mm; opercular diameter, 3 mm; 60 radii (36– 46 –60, s.d. = 9.08, N = 5, radii).—Mediterranean: Much Levant Mediterranean material in the National Natural History Collections of the Hebrew University of Jerusalem presently determined as Serpula vermicularis (see Ben-Eliahu & ten Hove 1992; Ben-Eliahu & Fiege 1996).
description: Published as part of Ben-Eliahu, M. Nechama & Ten Hove, Harry A., 2011, Serpulidae (Annelida: Polychaeta) from the Suez Canal- From a Lessepsian Migration Perspective (a Monograph) 2848, pp. 1-147 in Zootaxa 2848 (1) on page 87, DOI: 10.11646/zootaxa.2848.1.1, http://zenodo.org/record/5287534
Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling
Creators: name: Manka, Szymon W.
name: Bihan, Dominique
name: Farndale, Richard W.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
/631/1647/2258/1267
/631/45
/631/535
article

description: Abstract: Matrix metalloproteinase-3 (MMP-3) participates in normal extracellular matrix turnover during embryonic development, organ morphogenesis and wound healing, and in tissue-destruction associated with aneurysm, cancer, arthritis and heart failure. Despite its inability to cleave triple-helical collagens, MMP-3 can still bind to them, but the mechanism, location and role of binding are not known. We used the Collagen Toolkits, libraries of triple-helical peptides that embrace the entire helical domains of collagens II and III, to map MMP-3 interaction sites. The enzyme recognises five sites on collagen II and three sites on collagen III. They share a glycine-phenylalanine-hydroxyproline/alanine (GFO/A) motif that is recognised by the enzyme in a context-dependent manner. Neither MMP-3 zymogen (proMMP-3) nor the individual catalytic (Cat) and hemopexin (Hpx) domains of MMP-3 interact with the peptides, revealing cooperative binding of both domains to the triple helix. The Toolkit binding data combined with molecular modelling enabled us to deduce the putative collagen-binding mode of MMP-3, where all three collagen chains make contacts with the enzyme in the valley running across both Cat and Hpx domains. The observed binding pattern casts light on how MMP-3 could regulate collagen turnover and compete with various collagen-binding proteins regulating cell adhesion and proliferation.
Stellar population models of Lick indices with variable element abundance ratios
Creators: name: Thomas, Daniel
name: Maraston, Claudia
name: Bender, Ralf
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We provide the whole set of Lick indices from CN1 to TiO2 of Simple Stellar Population models with, for the first time, variable element abundance ratios, [alpha/Fe]=0.0, 0.3, 0.5, [alpha/Ca]=-0.1, 0.0, 0.2, 0.5, and [alpha/N]=-0.5, 0.0. The models cover ages between 1 and 15 Gyr, metallicities between 1/200 and 3.5 solar. Our models are free from the intrinsic alpha/Fe bias that was imposed by the Milky Way template stars up to now, hence they reflect well-defined alpha/Fe ratios at all metallicities. The models are calibrated with Milky Way globular clusters for which metallicities and alpha/Fe ratios are known from independent spectroscopy of individual stars. The metallicities that we derive from the Lick indices Mgb and Fe5270 are in excellent agreement with the metallicity scale by Zinn & West (1984), and we show that the latter provides total metallicity rather than iron abundance. We can reproduce the relatively strong CN-absorption features CN1 and CN2 of galactic globular clusters with models in which nitrogen is enhanced by a factor three. An enhancement of carbon, instead, would lead to serious inconsistencies with the indices Mg1 and C24668. The calcium sensitive index Ca4227 of globular clusters is well matched by our models with [Ca/Fe]= 0.3, including the metal-rich Bulge clusters NGC 6528 and NGC 6553. From our alpha/Fe enhanced models we infer that the index [MgFe] defined by Gonzalez (1993) is quite independent of alpha/Fe, but still slightly decreases with increasing alpha/Fe. We define a slight modification of this index that is completely independent of alpha/Fe and serves best as a tracer of total metallicity. Searching for blue indices that give similar information as Mgb and Fe, we find that CN1 and Fe4383 may be best suited to estimate alpha/Fe ratios of objects at redshifts z~1. (Abridged)
description: 17 pages, 7 figures, plus 8 pages model tables. Accepted by MNRAS. Models are also available in at ftp://ftp.mpe.mpg.de/people/dthomas/SSPs
Theoretical approaches to hadrons in nuclear matter
Creators: name: Chanfray, G.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We discuss recent developments concerning the in-medium properties of hadrons in dense and hot matter. The theoretical approaches are discussed in connection with the interpretation of experimental data from intermediate energy machines up to relativistic heavy ion collisions. Special emphasis is put on chiral restoration and its interplay with the substructure of the nucleon.
description: Pleanary talk presented at PANIC02, Sept 30- Oct 4, Osaka, Japan. To appear in the proceedings in Nuclear Physics A
Additional file 1: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets
Creators: name: Perconti, Giovanni
name: Rubino, Patrizia
name: Contino, Flavia
name: Bivona, Serena
name: Bertolazzi, Giorgio
name: Tumminello, Michele
name: Feo, Salvatore
name: Giallongo, Agata
name: Coronnello, Claudia
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Analysis of miRNA expression in AGO2 and GW182-IP samples. a) miRNA expression level in AGO2-IP samples (average value from the three performed experiments) vs the expression level in IN samples (average value from the three performed experiments). The Pearson correlation values reported on the top of the picture were computed by using all the expressed miRNA, and the top 100 or 50 expressed miRNAs. The colored points refer to miRNA that have been validated by RT-PCR data. Green points refer to hsa-miR-141-3p, hsa-miR-21-5p, hsa-let-7f-5p, hsa-miR-16-5p, hsa-miR-24-3p, hsa-miR-27a-3p, hsa-miR-23a-3p. The red point refers to hsa-miR-1260a. b) Comparison of IP/IN ratios obtained by RT-PCR data (normalized by IgG control data) and microarray data (normalized by Quantile normalization). The underrepresentation of hsa-miR-1260a was confirmed by RT-PCR. c) and d) Analysis of GW182-IP samples performed as described in a) and b). (PDF 47 kb)
La catalogazione dei manoscritti delle opere di Agostino conservati presso la Biblioteca Capitolare di Verona
Creators: name: Tronca, Donatella
Publisher: name: Zenodo
Year: 2013
Subjects: Biblioteca Capitolare Verona
Augustine of Hippo
manuscripts

description: The seven manuscript codices analysed in this paper are held at the Cathedral Library of Verona and cover a period of time ranging from the beginning of the V century to the mid-IX century. They are described from a physical, textual and historical perspective. One of the benefits of this approach is that additional elements can be considered, leading to a more in-depth understanding of figures such as archdeacon Pacificus and institutions like the scriptorium in Verona in the Early Middle Ages. In this respect, the study of marginalia played a central role in providing tangible evidence of reading practices. Furthermore, the description of each codex as a unique item which is more than a simple passive container reveals the history of the manuscript; it is this history that enables us to carry out a proper assessment of the codex as a witness to the work or works that it bequeaths.
Thermodynamic entropy as a Noether invariant in a Langevin equation
Creators: name: Minami, Yuki
name: Sasa, Shin-ichi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the thermodynamic entropy as a Noether invariant in a stochastic process. Following the Onsager theory, we consider the Langevin equation for a thermodynamic variable in a thermally isolated system. By analyzing the Martin-Siggia-Rose-Janssen-de Dominicis action of the Langevin equation, we find that this action possesses a continuous symmetry in quasi-static processes, which leads to the thermodynamic entropy as the Noether invariant for the symmetry.
description: 12 pages, 2 figures
Calculation of mode coupling for quadrupole excitations in a Bose-Einstein condensate
Creators: name: Hechenblaikner, G.
name: Morgan, S. A.
name: Hodby, E.
name: Marago, O. M.
name: Foot, C. J.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: In this paper we give a theoretical description of resonant coupling between two collective excitations of a Bose condensed gas (BEC) on, or close, to a second harmonic resonance. Using analytic expressions for the quasi-particle wavefunctions we show that the coupling between quadrupole modes is strong, leading to a coupling time of a few milliseconds (for a TOP trap with radial frequency 100 Hz and 10^4 atoms). Using the hydrodynamic approximation, we derive analytic expression for the coupling matrix element. These can be used with an effective Hamiltonian (that we also derive) to describe the dynamics of the coupling process and the associated squeezing effects.
description: 12 pages, 3 figures
The Medium-Term Impact of COVID-19 Lockdown on Referrals to Secondary Care Mental Health Services: A Controlled Interrupted Time Series Study
Creators: name: Chen, Shanquan
name: She, Rui
name: Qin, Pei
name: Kershenbaum, Anne
name: Fernandez-Egea, Emilio
name: Nelder, Jenny R.
name: Ma, Chuoxin
name: Lewis, Jonathan
name: Wang, Chaoqun
name: Cardinal, Rudolf N.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Psychiatry
COVID-19/SARS-CoV-2 coronavirus pandemic
lockdown
secondary care mental health services
controlled interrupted time series analysis
comorbidity

description: To date, there is a paucity of information regarding the effect of COVID-19 or lockdown on mental disorders. We aimed to quantify the medium-term impact of lockdown on referrals to secondary care mental health clinical services. We conducted a controlled interrupted time series study using data from Cambridgeshire and Peterborough NHS Foundation Trust (CPFT), UK (catchment population ~0.86 million). The UK lockdown resulted in an instantaneous drop in mental health referrals but then a longer-term acceleration in the referral rate (by 1.21 referrals per day per day, 95% confidence interval [CI] 0.41–2.02). This acceleration was primarily for urgent or emergency referrals (acceleration 0.96, CI 0.39–1.54), including referrals to liaison psychiatry (0.68, CI 0.35–1.02) and mental health crisis teams (0.61, CI 0.20–1.02). The acceleration was significant for females (0.56, CI 0.04–1.08), males (0.64, CI 0.05–1.22), working-age adults (0.93, CI 0.42–1.43), people of White ethnicity (0.98, CI 0.32–1.65), those living alone (1.26, CI 0.52–2.00), and those who had pre-existing depression (0.78, CI 0.19–1.38), severe mental illness (0.67, CI 0.19–1.15), hypertension/cardiovascular/cerebrovascular disease (0.56, CI 0.24–0.89), personality disorders (0.32, CI 0.12–0.51), asthma/chronic obstructive pulmonary disease (0.28, CI 0.08–0.49), dyslipidemia (0.26, CI 0.04–0.47), anxiety (0.21, CI 0.08–0.34), substance misuse (0.21, CI 0.08–0.34), or reactions to severe stress (0.17, CI 0.01–0.32). No significant post-lockdown acceleration was observed for children/adolescents, older adults, people of ethnic minorities, married/cohabiting people, and those who had previous/pre-existing dementia, diabetes, cancer, eating disorder, a history of self-harm, or intellectual disability. This evidence may help service planning and policy-making, including preparation for any future lockdown in response to outbreaks.
Mechanisms for electron transport in atomic-scale one-dimensional wires: soliton and polaron effects
Creators: name: Ness, H.
name: Fisher, A. J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We study one-electron tunneling through atomic-scale one-dimensional wires in the presence of coherent electron-phonon (e-ph) coupling. We use a full quantum model for the e-ph interaction within the wire with open boundary conditions. We illustrate the mechanisms of transport in the context of molecular wires subject to boundary conditions imposing the presence of a soliton defect in the molecule. Competition between polarons and solitons in the coherent transport is examined. The transport mechanisms proposed are generally applicable to other one-dimensional nanoscale systems with strong e-ph coupling.
description: 7 pages, 4 figures, accepted for publication in Europhys. Lett
Flavoperla triangulata Liu & Yan & Li 2019, sp. nov.
Creators: name: Liu, Hao
name: Yan, Yanhua
name: Li, Weihai
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Perlidae
Flavoperla
Flavoperla triangulata

description: Flavoperla triangulata sp. nov. (Figs. 10–18) Adult habitus. General color yellowish brown (Fig. 10). Head mostly pale with a triangular brown marking between ocelli, and a smaller pale brown obscure area between frontoclypeus and M-line; compound eyes dark, ocelli with dark rings; antennae brown (Figs. 10–11). Pronotum brown, rectangular except lateral areas paler, with pale brown rugosities and a pair of brown lines along anterior and posterior margins (Fig. 11). Wings hyaline, veins brown; legs pale. Male. Body length 8.6–8.9 mm; forewing length 10.8–11.1 mm; hindwing length 9.6–9.8 mm. Hammer basal half brown with wing-shaped anterolateral extensions; apical half mostly unpigmented; subapex distinctly tapering and nipple-like covered by numerous brown spinules; apex slightly swollen and turned upward in lateral view (Figs. 13–14). Sternum 9 sclerotized except medial portion membranous with broadly rounded apical process. Epiproct sclerite brown and subtriangular, divided into two small subtriangles by a slender and membranous band; anterior margin set between bases of paired dark brown triangular spines (Fig. 12). Paraprocts short, curved forward with small apical hooks (Fig. 12). Dorsum aedeagus with a pair of short vertical sclerites medially (Fig. 16), ventrally gourd-shaped and gradually tapering to an obtuse triangular tip with two rounded processes in basolateral area (Figs. 13, 15), aedeagus curved upward in lateral view (Fig. 17), in caudal view with a small “fish mouth-shaped mark” (Fig. 18). Female. Unknown. Larva. Unknown. Type material. Holotype male (HIST), CHINA: Shaanxi, Qinling Mountain, Pinglianghe Forestry Station at Ningshan County, 18.7070 N, 108.8247 E, 2012. VII.13, light trap, Weihai Li. Paratypes: 2 males, same data as holotype (HIST). Etymology. The specific name refers to the shape of marking on the head. “Tri” in Latin means three and “angulus” means an angle. Distribution. China (Shaanxi). Remarks. See above.
description: Published as part of Liu, Hao, Yan, Yanhua & Li, Weihai, 2019, Two new species of Flavoperla (Plecoptera: Perlidae) from Shaanxi Province of China, pp. 395-400 in Zootaxa 4614 (2) on page 398, DOI: 10.11646/zootaxa.4614.2.8, http://zenodo.org/record/3242496
Flicker fusion thresholds as a clinical identifier of a magnocellular-deficit dyslexic subgroup
Creators: name: Peters, Jessica L.
name: Bavin, Edith L.
name: Brown, Alyse
name: Crewther, David P.
name: Crewther, Sheila G.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/378
/631/477
article

description: Abstract: The magnocellular-dorsal system is well isolated by high temporal frequency. However, temporal processing thresholds have seldom been explored in developmental dyslexia nor its subtypes. Hence, performances on two, four-alternative forced-choice achromatic flicker fusion threshold tasks modulated at low (5%) and high (75%) temporal contrast were compared in dyslexic and neurotypical children individually matched for age and intelligence (8–12 years, n = 54 per group). As expected, the higher modulation resulted in higher flicker fusion thresholds in both groups. Compared to neurotypicals, the dyslexic group displayed significantly lower ability to detect flicker at high temporal frequencies, both at low and high temporal contrast. Yet, discriminant analysis did not adequately distinguish the dyslexics from neurotypicals, on the basis of flicker thresholds alone. Rather, two distinct dyslexic subgroups were identified by cluster analysis – one characterised by significantly lower temporal frequency thresholds than neurotypicals (referred to as ‘Magnocellular-Deficit’ dyslexics; 53.7%), while the other group (‘Magnocellular-Typical’ dyslexics; 46.3%) had comparable thresholds to neurotypicals. The two dyslexic subgroups were not differentially associated with phonological or naming speed subtypes and showed comparable mean reading rate impairments. However, correlations between low modulation flicker fusion threshold and reading rate for the two subgroups were significantly different (p = .0009). Flicker fusion threshold performances also showed strong classification accuracy (79.3%) in dissociating the Magnocellular-Deficit dyslexics and neurotypicals. We propose that temporal visual processing impairments characterize a previously unidentified subgroup of dyslexia and suggest that measurement of flicker fusion thresholds could be used clinically to assist early diagnosis and appropriate treatment recommendations for dyslexia.
epBRM: Improving a Quality of 3D Object Detection using End Point Box Regression Module
Creators: name: Shin, Kiwoo
name: Tomizuka, Masayoshi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: We present an endpoint box regression module(epBRM), which is designed for predicting precise 3D bounding boxes using raw LiDAR 3D point clouds. The proposed epBRM is built with sequence of small networks and is computationally lightweight. Our approach can improve a 3D object detection performance by predicting more precise 3D bounding box coordinates. The proposed approach requires 40 minutes of training to improve the detection performance. Moreover, epBRM imposes less than 12ms to network inference time for up-to 20 objects. The proposed approach utilizes a spatial transformation mechanism to simplify the box regression task. Adopting spatial transformation mechanism into epBRM makes it possible to improve the quality of detection with a small sized network. We conduct in-depth analysis of the effect of various spatial transformation mechanisms applied on raw LiDAR 3D point clouds. We also evaluate the proposed epBRM by applying it to several state-of-the-art 3D object detection systems. We evaluate our approach on KITTI dataset, a standard 3D object detection benchmark for autonomous vehicles. The proposed epBRM enhances the overlaps between ground truth bounding boxes and detected bounding boxes, and improves 3D object detection. Our proposed method evaluated in KITTI test server outperforms current state-of-the-art approaches.
Microcapsulated biocides for the targeted control of invasive bivalves
Creators: name: Tang, Feng
name: Aldridge, David C.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
/631/158/2178
/704/158/2178
article

description: Funder: Gulbenkian Yuval Cambridge Studentship
description: Funder: Dawson Lectureship at St. Catharine’s College
description: Abstract: Invasive alien species (IAS) are one of the greatest drivers of ecological change. Typically, control uses chemical agents that often are ineffective, harmful to non-target organisms, and environmentally persistent. Bivalves are frequently high impact IAS, but have proven particularly hard to control due to their valve-closing response when exposed to conventional control agents. Microencapsulation of biocides with edible coatings represents a highly targeted delivery route, bypassing avoidance responses and accumulating in bivalves through their prodigious filter feeding. Uneaten microcapsules degrade and become biologically inactive within hours thus reducing potential impacts on non-target biota. We manufactured two new formulations of microcapsules (BioBullets). Particles were designed to mimic natural food particles (algae) in terms of size (9.5 ± 0.5 to 19.4 ± 1.3 SE µm diameter), buoyancy (near neutral) and shape (spherical). Laboratory exposures demonstrated that two formulations effectively controlled the Gulf wedge clam Rangia cuneata, an IAS currently spreading rapidly through Europe. A single dose of 2–6 mg L−1 of the active ingredient in a static system achieved 90% mortality after 30 days of exposure. Microencapsulation offers an effective and targeted management tool for rapid responses following the early detection of both Gulf wedge clams and many other filter-feeding IAS, and may be especially effective in closed systems or where populations remain very localised.
Spirobranchus giganteus
Creators: name: Ben-Eliahu, M. Nechama
name: Ten Hove, Harry A.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Polychaeta
Sabellida
Serpulidae
Spirobranchus
Spirobranchus giganteus

description: Spirobranchus giganteus (Pallas, 1776)
 Type locality. West Indies. Not present in the Suez Canal, but see Spirobranchus tetraceros .
description: Published as part of Ben-Eliahu, M. Nechama & Ten Hove, Harry A., 2011, Serpulidae (Annelida: Polychaeta) from the Suez Canal- From a Lessepsian Migration Perspective (a Monograph) 2848, pp. 1-147 in Zootaxa 2848 (1) on page 88, DOI: 10.11646/zootaxa.2848.1.1, http://zenodo.org/record/5287534
The magnetic response of disordered metallic rings: the large contribution of the far levels
Creators: name: Schechter, M.
name: Oreg, Y.
name: Imry, Y.
name: Levinson, Y.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We calculate the orbital linear magnetic response of disordered metallic rings to an Aharonov-Bohm flux using the BCS model for attractive electron-electron interaction. The contribution of all levels including those up to a high energy cutoff results in a much larger value than previously obtained using the local interaction model. The possible relevance of our results to the resolution of the discrepancy between the experimental and theoretical values for the ensemble-averaged persistent currents in these systems is discussed.
description: Submitted to PRL
Combinatorial operad actions on cochains
Creators: name: Berger, Clemens
name: Fresse, Benoit
Publisher: name: arXiv
Year: 2001
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55U10, 18C10, 18G55

description: A classical E-infinity operad is formed by the bar construction of the symmetric groups. Such an operad has been introduced by M. Barratt and P. Eccles in the context of simplicial sets in order to have an analogue of the Milnor FK-construction for infinite loop spaces. The purpose of this article is to prove that the associative algebra structure on the normalized cochain complex of a simplicial set extends to the structure of an algebra over the Barratt-Eccles operad. We also prove that differential graded algebras over the Barratt-Eccles operad form a closed model category. Similar results hold for the normalized Hochschild cochain complex of an associative algebra. More precisely, the Hochschild cochain complex is acted on by a suboperad of the Barratt-Eccles operad which is equivalent to the classical little squares operad.
description: 46 pages. Final version
Additional file 3: of Characterisation of three novel α-L-arabinofuranosidases from a compost metagenome
Creators: name: Fortune, Brent
name: Sizwe Mhlongo
name: Zyl, Leonardo
name: Huddy, Robert
name: Smart, Mariette
name: Trindade, Marla
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology

description: Figure S3. Michaelis-Menten plots of AFase-D3, −E3 and -H4. The kinetics of each enzyme was determined at their respective pH and temperature optima with increasing amounts of pNP-α-L-arabinofuranoside (mM). (n = 3) ± standard error. (DOCX 72 kb)