Protocol: Medication errors in pediatric anesthesia: a systematic scoping review with qualitative synthesis
Creators: name: Shawahna, Ramzi
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medical Sciences
subject: Anesthesiology
subject: Medicine and Health Sciences
subject: Medical Specialties
subject: Pediatrics
subject: Health and Medical Administration
subject: Medical Pharmacology
subject: Surgery

description: Protocol: Medication errors in pediatric anesthesia: a systematic scoping review with qualitative synthesis Author: Ramzi Shawahna, Mohammad Jaber, Eman Jumaa, Bisan Antari -------------------------------------------------- PROTOCOL -------------------------------------------- Background Safety of patients in hospitals has been placed at top priority in all healthcare systems around the world. However, incidence of medication errors in hospitals threaten the safety of patients, notably, pediatric patients (Alghamdi et al. 2019, Gates et al. 2018). Medication errors occur with almost all types of medications administered to patients in hospitalized settings including those administered during anesthesia (Feinstein et al. 2018, Gariel et al. 2018, Webster et al. 2001). So far, little is known on the occurrence of medications errors in hospitalized pediatric settings, notably, medication errors during anesthesia. Objectives In this systematic scoping review, we aim to: - Collect, describe, and summarize studies reporting on medication errors in pediatric anesthesia - Describe the nature of medication errors situations that occur in pediatric anesthesia - Synthesize recommendations to minimize medication errors in pediatric anesthesia Methods Strategy of the literature search Databases COCHRANE, MEDLINE/PUBMED, EMBASE, CInAHL/EBESCO, and PsycINFO will be searched. Keywords Keywords relevant to medication errors and anesthesia will be searched. Boolean operators will be used to combine the keywords. The results will be filtered for those relevant to the pediatric population. Google Scholar database will be searched to identify studies from the gray literature. References of the collected studies will be searched manually. Study selection The identified studies will be screened by at least two researchers independently. Studies will be imported as Research Information Systems (RIS) and Comma Separated Values (CSV) files. Duplicates will be removed. Discrepancies will be resolved by discussion and consensus. Inclusion criteria - Studies reporting on medication errors in pediatric anesthesia - Studies reporting on strategies to reduce medication errors in pediatric anesthesia Exclusion Criteria - Studies will be filtered for human studies - Studies will be filtered for pediatric populaitons Data extraction and data synthesis At least two researchers will independently extract data into standardized data extraction form in Microsoft Excel Spreadsheet. Medication error situations will be described qualitatively into scenarios in the context of how these errors occurred. Discrepancies will be resolved by discussion and consensus. Similarly, recommendations to minimize medication errors in pediatric anesthesia will be synthesized qualitatively (Shawahna 2020, Shawahna et al. 2021). Grading recommendations by level of evidence At least two researchers will independently grade the recommendations by level of evidence using the Joanna Briggs Institute methodology. Discrepancies will be resolved by discussion and consensus (JBI 2014, Munn et al. 2019). Discussion This is the first systematic scoping review that will be conducted to collect, describe, and summarize studies reporting on medication errors in pediatric anesthesia, describe the nature of medication errors situations that occur in pediatric anesthesia, and synthesize recommendations to minimize medication errors in pediatric anesthesia. Findings of this study might be informative to decision makers in healthcare authorities, anesthesiologists, nurses, pharmacists, and pharmaceutical industry who might be interested in minimizing medication errors in pediatric anesthesia. References Alghamdi AA, Keers RN, Sutherland A &amp; Ashcroft DM (2019): Prevalence and Nature of Medication Errors and Preventable Adverse Drug Events in Paediatric and Neonatal Intensive Care Settings: A Systematic Review. Drug Safety 42, 1423-1436. Feinstein MM, Pannunzio AE &amp; Castro P (2018): Frequency of medication error in pediatric anesthesia: A systematic review and meta-analytic estimate. Paediatr Anaesth 28, 1071-1077. Gariel C, Cogniat B, Desgranges FP, Chassard D &amp; Bouvet L (2018): Incidence, characteristics, and predictive factors for medication errors in paediatric anaesthesia: a prospective incident monitoring study. Br J Anaesth 120, 563-570. Gates PJ, Meyerson SA, Baysari MT, Lehmann CU &amp; Westbrook JI (2018): Preventable Adverse Drug Events Among Inpatients: A Systematic Review. Pediatrics 142. JBI (2014) JBI EBP Database Guide. JBI. Available at: http://ospguides.ovid.com/OSPguides/jbidb.htm (accessed May 01, 2021. 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