cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Event and Anomaly Detection Using Tucker3 Decomposition
Creators: name: Fanaee-T, Hadi
name: Oliveira, Márcia D. B.
name: Gama, João
name: Malinowski, Simon
name: Morla, Ricardo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Failure detection in telecommunication networks is a vital task. So far, several supervised and unsupervised solutions have been provided for discovering failures in such networks. Among them unsupervised approaches has attracted more attention since no label data is required. Often, network devices are not able to provide information about the type of failure. In such cases the type of failure is not known in advance and the unsupervised setting is more appropriate for diagnosis. Among unsupervised approaches, Principal Component Analysis (PCA) is a well-known solution which has been widely used in the anomaly detection literature and can be applied to matrix data (e.g. Users-Features). However, one of the important properties of network data is their temporal sequential nature. So considering the interaction of dimensions over a third dimension, such as time, may provide us better insights into the nature of network failures. In this paper we demonstrate the power of three-way analysis to detect events and anomalies in time-evolving network data.
Il Museo delle Navi romane di Nemi. Passato presente e futuro
Creators: name: De Angelis, Daniela
Publisher: name: La Rivista di Engramma
Year: 2023
Subjects: Nemi ships Museum
PNRR
Funding
Projects

description: Daniela De Angelis, Director of the Nemi ships Museum, recalls the history of the building and describes the issues related with its conservation. Research is being conducted in the main archives, in order to enlarge the knowledge of the building in its historical phases. In the next years, thanks to the PNRR funds, several restoration works are planned, involving impermeabilization of the roofs, structural consolidation, and setting of the ehibitions.
A simple mechanism leading to first-order phase transitions in a model of tax evasion
Creators: name: Crokidakis, Nuno
Publisher: name: arXiv
Year: 2021
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: In this work we study a dynamics of tax evasion. We considered a fully-connected population divided in three compartments, namely honest tax payers, tax evaders and susceptibles, a class that is composed by honest tax payers that can become evaders. We consider a contagion model where the transitions among the compartments are governed by probabilities. Such probabilities represent the possible interactions among the indiviudals, as well as the government's fiscalization. We show by analytical and numerical calculations that the emergence of tax evaders in the population is associated with an active-absorbing nonequilibrium first-order phase transition. In the absorbing phase only honest tax payers survive in the steady states of the model, and we observe a coexistence of the three subpopulations in the active phase.
description: 12 pages, 3 figures, to appear in IJMPC. arXiv admin note: text overlap with arXiv:1609.04338
Linkage Analysis of Glomerular Filtration Rate in American Indians: The Strong Heart Family Study
Creators: name: Almasy, Laura
name: Laston, Sandra
name: Franceschini, Nora
name: Diego, Vincent P.
name: Cole, Shelley A.
name: Fabsitz, Richard R.
name: Best, Lyle G.
name: Mottl, Amy K.
name: MacCluer, Jean W.
name: North, Kari E.
name: Göring, Harald H.H.
name: Vupputuri, Suma
name: Lee, Elisa T.
name: Umans, Jason G.
name: Shara, Nawar M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: American Indians have a disproportionately high rate of kidney disease likely due to a combination of increased environmental and genetic risk factors. In an attempt to localize genes influencing kidney disease risk factors, we performed a genome wide scan of estimated glomerular filtration rate on participants of the Strong Heart Family Study. Over 3 600 men and women from 13 American Indian tribes were recruited from 3 centers (Arizona, North and South Dakota, Oklahoma). Using SOLAR 2.1.2, multipoint variance component linkage analysis was performed in each center as well as the entire cohort after controlling for center effects. Two modeling strategies were utilized: model 1 incorporated age, sex and interaction terms and model 2 additionally controlled for diabetic status, systolic and diastolic blood pressure, body mass index, low density lipoproteins, high density lipoproteins, triglycerides and smoking status. Significant evidence for linkage in Arizona lay on 12p12.2 at 39cM nearest marker D12S310 (LOD=3.5). Additional loci with suggestive evidence for linkage were detected at 1p36.31 (LOD=2.0–2.3), 2q33.3 (LOD=1.8) and 9q34.2 (LOD=2.4). No significant evidence for additive interaction with diabetes, hypertension or obesity was noted. In conclusion, we found evidence for linkage of a quantitative trait locus influencing estimated glomerular filtration rate to a region of chromosome 12p in a large cohort of American Indians.
The clinical course of ANCA small-vessel vasculitis on chronic dialysis
Creators: name: Hu, Yichun
name: Lionaki, Sofia
name: Nachman, Patrick H.
name: Hogan, Susan L.
name: Hamra, Julie B.
name: Charles Jennette, J.
name: Falk, Ronald J.
name: Jennette, Caroline E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Antineutrophil cytoplasmic autoantibody (ANCA)-associated small-vessel vasculitis frequently affects the kidney. Here we describe the rates of infection, disease relapse, and death in patients with ANCA small-vessel vasculitis before and after end-stage renal disease (ESRD) in an inception cohort study and compare them to those of patients with preserved renal function. All patients had biopsy-proven ANCA small-vessel vasculitis. Fisher's exact tests and Wilcoxon rank sum tests were used to compare the characteristics by ESRD status. ESRD follow-up included time on dialysis with transplants censored. Over a median follow-up time of 40 months, 136 of 523 patients reached ESRD. ESRD was associated with new-onset ANCA small-vessel vasculitis in 51% of patients, progressive chronic kidney disease without active vasculitis in 43%, and renal relapse in 6% of patients. Relapse rates of ANCA small-vessel vasculitis, reported as episodes/person-year, were significantly lower on chronic dialysis (0.08 episodes) compared with the rate of the same patients before ESRD (0.20 episodes) or with patients with preserved renal function (0.16 episodes). Infections were almost twice as frequent among patients with ESRD on maintenance immunosuppressants and were an important cause of death. Given the lower risk of relapse and higher risk of infection and death, we suggest that immunosuppression be geared to patients with ESRD who present with active vasculitis.
The kallikrein–kinin system in health and in diseases of the kidney
Creators: name: Smithies, Oliver
name: Kakoki, Masao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Since kallikrein was discovered as a vasodilatory substance in human urine, the kallikrein–kinin system (KKS) has been considered to play a physiological role in controlling blood pressure. Gene targeting experiments in mice in which the KKS has been inactivated to varying degrees have, however, questioned this role, because basal blood pressures are not altered. Rather, these experiments have shown that the KKS has a different and important role in preventing changes associated with normal senescence in mice, and in reducing the nephropathy and accelerated senescence-associated phenotypes induced in mice by diabetes. Other experiments have shown that the KKS suppresses mitochondrial respiration, partly by nitric oxide and prostaglandins, and that this suppression may be a key to understanding how the KKS influences senescence-related diseases. Here we review the logical progression and experimental data leading to these conclusions, and discuss their relevance to human conditions.
Information Waste Management for Product Transportation by Applying the Digital Supply Chains and PDCA cycle: A Case Study of Franchise Shabu Stick, Bangkok
Creators: name: Phattaraporn Trisakul And Panutporn Ruangchoengchum
Publisher: name: MSMIS Thammasat University
Year: 2566
Subjects: Information waste
Error
Digital supply chains
PDCA cycle
Franchise Shabu stick

description: Journal of information systems in Business JISB, 9, 2, 6
Sugar-sweetened soda consumption, hyperuricemia, and kidney disease
Creators: name: Derebail, Vimal K.
name: Anderson, Cheryl A.
name: Rosamond, Wayne D.
name: Bomback, Andrew S.
name: Steffen, Lyn M.
name: Shoham, David A.
name: Kshirsagar, Abhijit V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The metabolism of high-fructose corn syrup used to sweeten soda drinks may lead to elevations in uric acid levels. Here we determined whether soda drinking is associated with hyperuricemia and, as a potential consequence, reduced kidney function. At baseline, 15,745 patients in the Atherosclerosis Risk in Communities Study completed a dietary questionnaire and had measurements of their serum creatinine and uric acid. After 3 and 9 years of follow-up, multivariate odds ratios from logistic regressions for binary outcome of hyperuricemia and chronic kidney disease (eGFR less than 60 ml/min per 1.73 m2) were evaluated. Compared to participants who drank less, consumption of over one soda per day was associated with increased odds of prevalent hyperuricemia and chronic kidney disease. The odds ratio for chronic kidney disease significantly increased to 2.59 among participants who drank more than one soda per day and had a serum uric acid level over 9.0 mg/dl. In longitudinal analyses, however, drinking more than one soda per day was not associated with hyperuricemia or chronic kidney disease. Neither preexistent hyperuricemia nor development of hyperuricemia modified the lack of association between soda drinking and incident chronic kidney disease. Thus our study shows that high consumption of sugar-sweetened soda was associated with prevalent but not incident hyperuricemia and chronic kidney disease.
Clinical trial of focal segmental glomerulosclerosis in children and young adults
Creators: name: Radeva, Milena K.
name: D'Agati, Vivette D.
name: Hogan, Susan L.
name: McMahan, June L.
name: Vento, Suzanne M.
name: Gassman, Jennifer J.
name: Flynn, Patti A.
name: Fine, Richard N.
name: Hogg, Ronald J.
name: Powell, Leslie M.
name: Greene, Tom H.
name: Gipson, Debbie S.
name: Siegel, Norman
name: Kaskel, Frederick J.
name: Moxey-Mims, Marva M.
name: Friedman, Aaron L.
name: Vehaskari, V. Matti
name: Middleton, John P.
name: Watkins, Sandra L.
name: Trachtman, Howard
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: This NIH-funded multicenter randomized study of focal segmental glomerulosclerosis (FSGS) treatment compared the efficacy of a 12-month course of cyclosporine to a combination of oral pulse dexamethasone and mycophenolate mofetil in children and adults with steroid-resistant primary FSGS. Of the 192 patients enrolled, 138 were randomized to cyclosporine (72) or to mycophenolate/dexamethasone (66). The primary analysis compared the levels of an ordinal variable measuring remission during the first year. The odds ratio (0.59) for achieving at least a partial remission with mycophenolate/dexamethasone compared to cyclosporine was not significant. Partial or complete remission was achieved in 22 mycophenolate/dexamethasone- and 33 cyclosporine-treated patients at 12 months. The main secondary outcome, preservation of remission for 26 weeks following cessation of treatment, was not significantly different between these two therapies. During the entire 78 weeks of study, 8 patients treated with cyclosporine and 7 with mycophenolate/dexamethasone died or developed kidney failure. Thus, our study did not find a difference in rates of proteinuria remission following 12 months of cyclosporine compared to mycophenolate/dexamethasone in patients with steroid-resistant FSGS. However, the small sample size might have prevented detection of a moderate treatment effect.
QUALITATIVE ANALYSIS OF BAKED CLAY BRICKS AVAILABLE IN LARKANA REGION, PAKISTAN
Creators: name: Khoso, Salim
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 400504
subject: Construction engineering
classificationCode: 400505
subject: Construction materials
classificationCode: 400507
subject: Fire safety engineering
classificationCode: 400510
subject: Structural engineering

description: Apparently in the beginning non-fired bricks were used for the shelter over the head. As the world progressed fired clay bricks found acceptability for construction. In Pakistan fired clay bricks are used in-plenty for erecting the houses. However, the technology is quite old and the practice is being repeated for several years. More commonly the bricks are porous; water absorbability is quite high and consequently the compressive strength and other properties are much lower than they should have been. In order to get an idea about quality of bricks, a comparative study of the properties of fired clay bricks of Hoofmann kiln versus Sada Bhatta (manually operated kiln) is done. A systematic study was carried out to determine various properties such as water absorption, efflorescence, crushing strength, specific weight, specific gravity of common bricks and specific weight of baked clay. This was particularly deemed imperative because of the fact that the process of burning is not uniform. This is done in two forms; i.e. by burning in the kiln with wooden logs and wooden fuels and in the Sada Bhattas where the fuel is bagasse and rice husks. Obviously it was expected that the compressive strength of bricks in the kiln was somewhat higher than Sada Bhattas. The systematic study consists of compressive strength, modulus of elasticity and Poisson's ratio as major points of investigations.
Privacy-preserving Federated Adversarial Domain Adaption over Feature Groups for Interpretability
Creators: name: Kang, Yan
name: Liu, Yang
name: Wu, Yuezhou
name: Ma, Guoqiang
name: Yang, Qiang
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We present a novel privacy-preserving federated adversarial domain adaptation approach ($\textbf{PrADA}$) to address an under-studied but practical cross-silo federated domain adaptation problem, in which the party of the target domain is insufficient in both samples and features. We address the lack-of-feature issue by extending the feature space through vertical federated learning with a feature-rich party and tackle the sample-scarce issue by performing adversarial domain adaptation from the sample-rich source party to the target party. In this work, we focus on financial applications where interpretability is critical. However, existing adversarial domain adaptation methods typically apply a single feature extractor to learn feature representations that are low-interpretable with respect to the target task. To improve interpretability, we exploit domain expertise to split the feature space into multiple groups that each holds relevant features, and we learn a semantically meaningful high-order feature from each feature group. In addition, we apply a feature extractor (along with a domain discriminator) for each feature group to enable a fine-grained domain adaptation. We design a secure protocol that enables performing the PrADA in a secure and efficient manner. We evaluate our approach on two tabular datasets. Experiments demonstrate both the effectiveness and practicality of our approach.
description: Published in IEEE Transactions on Big Data
Circular dichroism in a three-dimensional semiconductor chiral photonic crystal
Creators: name: Takahashi, S.
name: Tajiri, T.
name: Ota, Y.
name: Tatebayashi, J.
name: Iwamoto, S.
name: Arakawa, Y.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Circular dichroism covering the telecommunication band is experimentally demonstrated in a semiconductor-based three-dimensional chiral photonic crystal (PhC). We design a rotationally-stacked woodpile PhC structure where neighboring layers are rotated by 60 degrees and three layers construct a single helical unit. The mirror-asymmetric PhC made from GaAs with sub-micron periodicity is fabricated by a micro-manipulation technique. Due to the large contrast of refractive indices between GaAs and air, the experimentally obtained circular dichroism extends over a wide wavelength range, with the transmittance of right-handed circularly polarized incident light being 85% and that of left-handed light being 15% at a wavelength of 1300 nm. The obtained results show good agreement with numerical simulations.
description: 4 pages, 4 figures
Spin transport enhancement by controlling the Ag growth in lateral spin valves
Creators: name: Isasa, Miren
name: Villamor, Estitxu
name: Fallarino, Lorenzo
name: Idigoras, Olatz
name: Suszka, Anna K.
name: Tollan, Christopher
name: Berger, Andreas
name: Hueso, Luis E.
name: Casanova, Fèlix
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The role of the growth conditions in the spin transport properties of silver (Ag) have been studied by using lateral spin valve structures. By changing the deposition conditions of Ag from polycrystalline to epitaxial growth, we have observed a considerable enhancement of the spin diffusion length, from $λ_{Ag}$ = 449 $\pm$ 30 to 823 $\pm$ 59 nm. This study shows that diminishing the grain boundary contribution to the spin relaxation mechanism is an effective way to improve the spin diffusion length in metallic nanostructures.
description: 6 pages, 3 figures
Clinical trials treating focal segmental glomerulosclerosis should measure patient quality of life
Creators: name: Middleton, John P.
name: McMahan, June L.
name: Greene, Tom H.
name: Gipson, Debbie S.
name: Watkins, Sandra L.
name: Hogan, Susan L.
name: Siegel, Norman
name: Radeva, Milena K.
name: Vento, Suzzane
name: Hogg, Ronald J.
name: Friedman, Aaron L.
name: Moxey-Mims, Marva M.
name: Gassman, Jennifer
name: Fine, Richard N.
name: Kaskel, Frederick J.
name: Flynn, Patti A.
name: Powell, Leslie M.
name: Trachtman, Howard
name: Vehaskari, V.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Optimal therapy of patients with steroid-resistant primary focal segmental glomerulosclerosis (FSGS) remains controversial. This report describes the initial study design, baseline characteristics, and quality of life of patients enrolled in the FSGS Clinical Trial, a large multicenter randomized study of this glomerulopathy comparing a 12-month regimen of cyclosporine to the combination of mycophenolate mofetil and oral dexamethasone. Patients with age ranging 2–40 years, with an estimated glomerular filtration rate >40 ml/min per 1.73 m2, a first morning urine protein-to-creatinine ratio over one, and resistant to corticosteroids were eligible. The primary outcome was complete or partial remission of proteinuria over 52 weeks after randomization. In all, 192 patients were screened, of whom 138 were randomized for treatment. Ethnic distributions were 53 black, 78 white, and 7 other. By self- or parent-proxy reporting, 26 of the 138 patients were identified as Hispanic. The baseline glomerular filtration rate was 112.4 (76.5, 180.0) ml/min per 1.73 m2, and urine protein was 4.0 (2.1, 5.3) g/g. Overall, the quality of life of the patients with FSGS was lower than healthy controls and similar to that of patients with end-stage renal disease. Thus, the impact of FSGS on quality of life is significant and this measurement should be included in all trials.
Accurate Determination of the Shear Viscosity of the One-Component Plasma
Creators: name: Daligault, Jerome
name: Rasmussen, Kim O.
name: Baalrud, Scott D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The shear viscosity coefficient of the one-component plasma is calculated with unprecedented accuracy using equilibrium molecular dynamics simulations and the Green-Kubo relation. Numerical and statistical uncertainties and their mitigation for improving accuracy are analyzed. In the weakly coupled regime, our the results agree with the Landau-Spitzer prediction. In the moderately and strongly coupled regimes, our results are found in good agreement with recent results obtained for the Yukawa one-component plasma using non-equilibrium molecular dynamics. A practical formula is provided for evaluating the viscosity coefficient across coupling regimes, from the weakly-coupled regime up to solidification threshold. The results are used to test theoretical predictions of the viscosity coefficients found in the literature.
description: 13 pages, 10 figures
Συνθετικά κανναβινοειδή: Στοιχεία φαρμακολογίας, τοξικότητα και μέθοδοι προσδιορισμού σε βιολογικά υλικά
Creators: name: Ασκοπούλου Μαρία Ελένη Παύλου
Publisher: name: Aristotle University of Thessaloniki
Year: 2023
Subjects: Νέες ψυχοδραστικές ουσίες
Συνθετικά Κανναβινοειδή
Τοξικοδυναμική
Φαρμακοδυναμική
new psychoactive substances,
Synthetic cannabinoids (SCs),
psychoactive substances (NPSs),
toxicodynamics,
pharmacodynamics

description: Τα συνθετικά κανναβινοειδή (SCs) είναι μια χημικά διαφορετική ομάδα νέων ψυχοδραστικών ουσιών (NPSs) που στοχεύουν το ενδοκανναβινοειδές σύστημα, ενεργοποιώντας μια πληθώρα δράσεων (π.χ. αυξημένη αίσθηση διάθεσης, χαλάρωση, διέγερση όρεξης) που μοιάζουν, αλλά είναι πιο έντονες που προκαλείται από την κάνναβη. Αν και ορισμένες από αυτές τις επιδράσεις έχουν διερευνηθεί για θεραπευτικές εφαρμογές, οι αναμενόμενες ισχυρότερες ψυχοδραστικές επιδράσεις από την κάνναβη και η μειωμένη αντίληψη κινδύνου έχουν αυξήσει την ψυχαγωγική χρήση των SC, τα οποία κυριάρχησαν στην αγορά NPS στις Ηνωμένες Πολιτείες και την Ευρώπη την τελευταία δεκαετία. Ωστόσο, οι αυξανόμενες δηλητηριάσεις και οι θάνατοι που σχετίζονται με το SC αντιπροσωπεύουν μια σημαντική ανησυχία για τη δημόσια υγεία και ενσωματώνουν μια σημαντική πρόκληση για τους υπεύθυνους χάραξης πολιτικής.Στην παρούσα εργασία εξετάζουμε τη φαρμακολογία και την τοξικολογία αυτών των ενώσεων. Ένας λεπτομερής χαρακτηρισμός της φαρμακοδυναμικής και της τοξικοδυναμικής των SCs είναι σημαντικός για την καλύτερη κατανόηση των κύριων μηχανισμών που κρύβουν τις οξείες και χρόνιες επιδράσεις των SC, για την ερμηνεία των κλινικών/παθολογικών ευρημάτων που σχετίζονται με τη χρήση του SC και για τη βελτίωση της ευαισθητοποίησης σχετικά με τον κίνδυνο των SC
description: Synthetic cannabinoids (SCs) are a group of new psychoactive substances (NPSs) that are chemically diverse and target the endocannabinoid system. They cause a variety of effects, such as elevated mood sensation, relaxation, and appetite stimulation, but they are stronger than those brought on by cannabis. The recreational use of SCs, which have dominated the NPS market in the US and Europe over the past ten years, has increased even though some of these effects have been investigated for therapeutic applications. These effects include stronger psychoactive effects than cannabis and reduced risk perception. However, the increasing number of SC-related intoxications and fatalities provide a significant issue for policymakers in terms of public health. We now go through the toxicology and pharmacology of SCs. To better comprehend the primary processes causing acute and long-term effects of SCs, interpret the clinical/pathological findings associated with SC use, and raise public awareness of SC danger, it is crucial to thoroughly characterize the pharmacodynamics and toxicodynamics of SCs
Customer Segmentation by K-MEANS Clustering: A Case Study of a Leasing Company in Thailand
Creators: name: Kanyaporn Kemcharoen
Publisher: name: MSMIS Thammasat University
Year: 2566
Subjects: Leasing
Clustering
Unsupervised learning
K-means
Cross-industry standard process for data mining (CRISP-DM)

description: Journal of information systems in Business JISB, 9, 2, 55
Additional file 4 of Predictors of hypotension during anesthesia induction in patients with hypertension on medication: a retrospective observational study
Creators: name: Hojo, Takayuki
name: Kimura, Yukifumi
name: Shibuya, Makiko
name: Fujisawa, Toshiaki
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 4: Supplementary Table 4. Details of multiple therapies.
Event-based anomaly detection for new physics searches at the LHC using machine learning
Creators: name: Chekanov, S. V.
name: Hopkins, W.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: This paper discusses model-agnostic searches for new physics at the Large Hadron Collider (LHC) using anomaly-detection techniques for the identification of event signatures that deviate from the Standard Model (SM). We investigate anomaly detection in the context of machine-learning approaches using autoencoders, and illustrate expected shapes of invariant masses in the outlier region using Monte Carlo simulations. Challenges and conceptual limitations of this approach are discussed.
description: 13 pages, 6 images, contribution to Snowmass 2022
Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans
Creators: name: Hicks, Pamela J.
name: Divers, Jasmin
name: Freedman, Barry I.
name: Bowden, Donald W.
name: Nachman, Patrick H.
name: Lu, Lingyi
name: Bleyer, Anthony J.
name: Derebail, Vimal K.
name: Langefeld, Carl D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Conflicting reports exist as to whether sickle cell trait is a risk factor for the progression of nephropathy. In order to determine whether African Americans with sickle cell trait are at increased risk for kidney disease, we assessed the genetic association between sickle cell trait and end-stage renal disease (ESRD). Hemoglobin S, non-muscle myosin heavy chain 9 (MYH9), and apolipoprotein L1 (APOL1) risk variants were genotyped in 3258 unrelated African Americans: 1085 with non-diabetic ESRD, 996 with type 2 diabetes-associated ESRD, and 1177 controls. Since APOL1 is strongly associated with ESRD in African Americans, interactions between APOL1 and MYH9 risk variants and hemoglobin S were assessed using case-only and case-control centered two-way logistic regression interaction analyses. The sickle cell trait genotype frequencies were 8.7% in non-diabetic ESRD, 7.1% in type 2 diabetes-ESRD, and 7.2% in controls. There was no age-, gender-, and admixture-adjusted significance for sickle cell trait association with non-diabetic ESRD (odds ratio 1.16); type 2 diabetes-ESRD (odds ratio 1.01); or all-cause ESRD (combined non-diabetic and type 2 diabetic-ESRD patients compared to the controls; odds ratio 1.05) in dominant models. In addition, no evidence of APOL1 or MYH9 interactions with sickle cell trait was detected. Hence, sickle cell trait is not associated with diabetic or non-diabetic ESRD in a large sample of African Americans.
Variant hemoglobin phenotypes may account for differential erythropoiesis-stimulating agent dosing in African-American hemodialysis patients
Creators: name: Ansede, Heather
name: Falk, Ronald J.
name: Kshirsagar, Abhijit V.
name: Key, Nigel S.
name: Nachman, Patrick H.
name: Derebail, Vimal K.
name: Rosamond, Wayne D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: African-American patients with end-stage renal disease have historically lower hemoglobin concentrations and higher requirements of erythropoiesis-stimulating agent (ESA). While disparities in health-care access may partially explain these findings, the role of variant hemoglobin, such as sickle trait, has not been investigated. To clarify this, we evaluated 154 African-American patients receiving in-center hemodialysis with available hemoglobin phenotyping. The primary exposure was any abnormal hemoglobin variant and the primary outcome of higher-dose ESA was defined as a dose of 6500 or more units per treatment. Logistic regression assessed the association between variant hemoglobin and higher-dose ESA. Covariates included age, gender, diabetes, iron parameters, intravenous iron dose, parathyroid hormone, albumin, phosphorus, body mass index, vascular access type, hospitalization/missed treatments, smoking status, alcohol abuse, and gastrointestinal bleeding. Of 33 patients with variant hemoglobin, 24 had HbAS and 9 had HbAC. Univariate odds of higher-dose ESA among those with hemoglobin variants were twice that of those with the normal HbAA phenotype (odds ratio 2.05). In multivariate models, the likelihood of higher-dose ESA had an odds ratio of 3.31 and the nature of this relationship did not change in Poisson regression or sensitivity analyses. Hence, our findings may explain, in part, the difference in ESA dosing between Caucasians and African-Americans with end-stage renal disease but await further study.
An ultra-weak sector, the strong CP problem and the pseudo-Goldstone dilaton
Creators: name: Allison, Kyle
name: Hill, Christopher T.
name: Ross, Graham G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the context of a Coleman-Weinberg mechanism for the Higgs boson mass, we address the strong CP problem. We show that a DFSZ-like invisible axion model with a gauge-singlet complex scalar field S, whose couplings to the Standard Model are naturally ultra-weak, can solve the strong CP problem and simultaneously generate acceptable electroweak symmetry breaking. The ultra-weak couplings of the singlet S are associated with underlying approximate shift symmetries that act as custodial symmetries and maintain technical naturalness. The model also contains a very light pseudo-Goldstone dilaton that is consistent with cosmological Polonyi bounds, and the axion can be the dark matter of the universe. We further outline how a SUSY version of this model, which may be required in the context of Grand Unification, can avoid introducing a hierarchy problem.
description: 9 pages
Bacterial Vaginosis: A Comprehensive Approach to Management in Reproductive-Aged Thai Women
Creators: name: Chenchit Chayachinda
Publisher: name: PIMDEE Co., Ltd.
Year: 2023
Subjects: bacterial vaginosis
Siriraj experience
treatment
vaginal dysbiosis
metronidazole

description: Thai Journal of Obstetrics and Gynaecology, 31, 5, 318-325
A Comparison of the LATCH Scores between Groups of Breastfeeding Women Using and Not Using a Nursing Pillow: A randomized, controlled trial
Creators: name: Supakit Sirikijkhajor
Publisher: name: PIMDEE Co., Ltd.
Year: 2023
Subjects: https://he02.tci-thaijo.org/index.php/tjog/article/view/261045/180242

description: Thai Journal of Obstetrics and Gynaecology, 31, 5, 326-333
Η διασυνοριακή απάτη σχετικά με τον ΦΠΑ
Creators: name: Φωτιάδου, Συμέλα-Μαρία Χρήστου
Publisher: name: Aristotle University of Thessaloniki
Year: 2023
Subjects: Διασυνοριακή απάτη περί τον ΦΠΑ
Οδηγία 2017/1371
Άρθρο 23 Ν. 4689/2020
Cross-border VAT fraud
PIF Directive 2017/1371
Article 23 of Law 4689/2020

description: Κέντρο ενδιαφέροντος της παρούσας διπλωματικής αποτελεί το αδίκημα της διασυνοριακής απάτης σχετικά με τον ΦΠΑ, όπως αυτό ενσωματώθηκε στην ελληνική έννομη τάξη με το άρθρο 23 Ν. 4689/2020, σε συμφωνία με τις προβλέψεις της Οδηγίας (ΕΕ)2017/1371, καθώς και τα σχετικά θέματα που έχουν ανακύψει ή προβλέπεται να ανακύψουν μελλοντικά, κατά την εφαρμογή του, τα οποία επιχειρούνται να αναλυθούν μέσα από τη θεωρητική αλλά και τη νομολογιακή τους προσέγγιση. Σε συμφωνία με τους ανωτέρω στόχους, το κύριο μέρος της παρούσας διπλωματικής εργασίας διαρθρώνεται σε τρία κεφάλαια, το πρώτο εκ των οποίων αφορά την ποινική αντιμετώπιση των προσβολών των οικονομικών συμφερόντων της ΕΕ και το γενικότερο πλαίσιο μέσα στο οποίο αυτή αναπτύχθηκε, δεδομένου ότι και το κοινό σύστημα ΦΠΑ, αλλά και το σχετικό αδίκημα οφείλονται στις πρωτοβουλίες της Ένωσης. Στο δεύτερο, από αυτά, κεφάλαιο επιχειρείται να εκτεθεί εν συντομία το καθεστώς λειτουργίας του ΦΠΑ, μέσα από την εκμετάλλευση του οποίου προκύπτουν τα φαινόμενα απάτης περί τον ΦΠΑ. Τέλος, το τρίτο κεφάλαιο πραγματεύεται το ειδικότερο αδίκημα της διασυνοριακής απάτης περί τον ΦΠΑ, έτσι όπως αυτό ενσωματώθηκε πλέον στην ελληνική έννομη τάξη, συμπεριλαμβανομένων των κυριότερων ζητημάτων που προκύπτουν κατά την εφαρμογή του σε σχέση και με τις λοιπές διατάξεις που τυγχάνουν εφαρμογής
description: The main focus of the present thesis is the offense of cross-border VAT fraud, as incorporated into the Greek legal order by the Article 23 of Law 4689/2020, in accordance with the provisions of Directive (EU)2017/1371, as well as the relevant issues that have arisen or are expected to arise in the future, during its implementation, which are attempted to be analyzed through their theoretical and case law approach. According to the above objectives, the main part of the present thesis is structured in three chapters, the first of which concerns the criminal treatment of violations of the EU's financial interests and the general framework within which it was developed, given that both the common VAT system and the related offence are due to Union initiatives. In the second chapter, it will be attempted to briefly explain the operation of VAT, through the exploitation of which the phenomena of VAT fraud arise. Finally, the third chapter deals with the specific offence of cross-border VAT fraud, as it has now been incorporated into the Greek legal order, including the main issues that are arising in its application in relation to the other provisions applicable
Additional file 5 of Predictors of hypotension during anesthesia induction in patients with hypertension on medication: a retrospective observational study
Creators: name: Hojo, Takayuki
name: Kimura, Yukifumi
name: Shibuya, Makiko
name: Fujisawa, Toshiaki
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 5: Supplementary Table 5. Baseline blood pressure data of patients receiving monotherapy and multiple therapies.
Unifying information propagation models on networks and influence maximization
Creators: name: Tian, Yu
name: Lambiotte, Renaud
Publisher: name: arXiv
Year: 2021
Subjects: subject: Social and Information Networks (cs.SI)
subject: Dynamical Systems (math.DS)
subject: Optimization and Control (math.OC)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 91D30, 90B10, 90C35, 90C56

description: Information propagation on networks is a central theme in social, behavioral, and economic sciences, with important theoretical and practical implications, such as the influence maximization problem for viral marketing. Here, we consider a model that unifies the classical independent cascade models and the linear threshold models, and generalise them by considering continuous variables and allowing feedback in the dynamics. We then formulate its influence maximization as a mixed integer nonlinear programming problem and adopt derivative-free methods. Furthermore, we show that the problem can be exactly solved in the special case of linear dynamics, where the selection criterion is closely related to the Katz centrality, and propose a customized direct search method with local convergence. We then demonstrate the close-to-optimal performance of the customized direct search numerically on both synthetic and real networks.
description: 28 pages, 22 figures
Causes of Secondary Amenorrhea: A report of 437 cases in Thailand
Creators: name: Mukpradab Darakamas
Publisher: name: PIMDEE Co., Ltd.
Year: 2023
Subjects: secondary amenorrhea
polycystic ovary syndrome
anovulation
hyperprolactinemia
premature ovarian insufficiency

description: Thai Journal of Obstetrics and Gynaecology, 31, 5, 334-340
Changes of Ovarian Reserve after Hysterectomy for Non-oncologic Conditions in Reproductive-aged Women: A prospective study
Creators: name: Natcha Silpaibulpanich
Publisher: name: PIMDEE Co., Ltd.
Year: 2023
Subjects: ovarian reserve
anti-mullerian hormone
ovarian volume
antral follicle count
hysterectomy

description: Thai Journal of Obstetrics and Gynaecology, 31, 5, 341-349
Boundary induced phase transition with stochastic entrance and exit
Creators: name: Mitra, Mithun Kumar
name: Chatterjee, Sakuntala
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We study an open-chain totally asymmetric exclusion process (TASEP) with stochastic gates present at the two boundaries. The gating dynamics has been modeled keeping the physical system of ion-channel gating in mind. These gates can randomly switch between an open state and a closed state. In the open state, the gates are highly permeable such that any particle arriving at the gate immediately passes through. In the closed state, a particle gets trapped at the gate and cannot pass through until the gate switches open again. We calculate the phase-diagram of the system and find important and non-trivial differences with the phase-diagram of a regular open-chain TASEP. In particular, depending on switching rates of the two gates, the system may or may not admit a maximal current phase. Our analytic calculation within mean-field theory captures the main qualitative features of our Monte Carlo simulation results. We also perform a refined mean-field calculation where the correlations at the boundaries are taken into account. This theory shows significantly better quantitative agreement with our simulation results.
Kalman Temporal Differences
Creators: name: Geist, Matthieu
name: Pietquin, Olivier
Publisher: name: arXiv
Year: 2014
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Because reinforcement learning suffers from a lack of scalability, online value (and Q-) function approximation has received increasing interest this last decade. This contribution introduces a novel approximation scheme, namely the Kalman Temporal Differences (KTD) framework, that exhibits the following features: sample-efficiency, non-linear approximation, non-stationarity handling and uncertainty management. A first KTD-based algorithm is provided for deterministic Markov Decision Processes (MDP) which produces biased estimates in the case of stochastic transitions. Than the eXtended KTD framework (XKTD), solving stochastic MDP, is described. Convergence is analyzed for special cases for both deterministic and stochastic transitions. Related algorithms are experimented on classical benchmarks. They compare favorably to the state of the art while exhibiting the announced features.
Additional file 1 of Global, regional, national burden and gender disparity of cataract: findings from the global burden of disease study 2019
Creators: name: Fang, Rui
name: Yu, Yang-Fan
name: Li, En-Jie
name: Lv, Ning-Xin
name: Liu, Zhao-Chuan
name: Zhou, Hong-Gang
name: Song, Xu-Dong
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1: Figure S1-3.
2-local triple derivations on von Neumann algebras
Creators: name: Kudaybergenov, Karimbergen
name: Oikhberg, Timur
name: Peralta, Antonio M.
name: Russo, Bernard
Publisher: name: arXiv
Year: 2014
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 46

description: We prove that every {\rm(}not necessarily linear nor continuous{\rm)} 2-local triple derivation on a von Neumann algebra $M$ is a triple derivation, equivalently, the set Der$_{t} (M)$, of all triple derivations on $M,$ is algebraically 2-reflexive in the set $\mathcal{M}(M)= M^M$ of all mappings from $M$ into $M$.
description: 16 pages
The InSight HP$^3$ mole on Mars: Lessons learned from attempts to penetrate to depth in the Martian soil
Creators: name: Spohn, T.
name: Hudson, T. L.
name: Witte, L.
name: Wippermann, T.
name: Wisniewski, L.
name: Kediziora, B.
name: Vrettos, C.
name: Lorenz, R. D.
name: Golombek, M.
name: Lichtenfeld, R.
name: Grott, M.
name: Knollenberg, J.
name: Krause, C.
name: Fantinati, C.
name: Nagihara, S.
name: Grygorczuk, J.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: The NASA InSight mission payload includes the Heat Flow and Physical Properties Package HP$^3$ to measure the surface heat flow. The package was designed to use a small penetrator -- nicknamed the mole -- to implement a string of temperature sensors in the soil to a depth of 5m. The mole itself is equipped with sensors to measure a thermal conductivity as it proceeds to depth. The heat flow would be calculated from the product of the temperature gradient and the thermal conductivity. To avoid the perturbation caused by annual surface temperature variations, the measurements would be taken at a depth between 3 m and 5 m. The mole was designed to penetrate cohesionless soil similar to Quartz sand which was expected to provide a good analogue material for Martian sand. The sand would provide friction to the buried mole hull to balance the remaining recoil of the mole hammer mechanism that drives the mole forward. Unfortunately, the mole did not penetrate more than a mole length of 40 cm. The failure to penetrate deeper was largely due to a few tens of centimeter thick cohesive duricrust that failed to provide the required friction. Although a suppressor mass and spring in the hammer mechanism absorbed much of the recoil, the available mass did not allow a system that would have eliminated the recoil. The mole penetrated to 40 cm depth benefiting from friction provided by springs in the support structure from which it was deployed. It was found in addition that the Martian soil provided unexpected levels of penetration resistance that would have motivated to designing a more powerful mole. It is concluded that more mass would have allowed to design a more robust system with little or no recoil, more energy of the mole hammer mechanism and a more massive support structure.
description: 34 pages, 15 figures, submitted to Adnaves in Space Research
Integrability and RG flow in 2d sigma models
Creators: name: Levine, Nathaniel
Publisher: name: Imperial College London
Year: 2021

description: Motivated by the search for solvable string theories, we consider the problem of classifying the integrable bosonic 2d sigma-models. We include non-conformal sigma-models, which have historically been a good arena for discovering integrable models that were later generalized to Weyl-invariant ones. General sigma-models feature a quantum RG flow, given by a 'generalized Ricci flow' of the target-space geometry. This thesis is based on the conjecture that integrable sigma-models are renormalizable, or stable under the RG flow. It is widely understood that classically integrable theories are stable at the leading 1-loop order with only a few parameters running. Here we address what happens at higher-loop orders. We find that integrable sigma-models generally remain RG-stable at higher-loops provided they receive a particular choice of finite counterterms, or quantum (alpha') corrections to the target-space geometry. Thought to be preserving integrability at the quantum level, these corrections are analogous to those required for higher-loop conformal invariance of gauged Wess-Zumino-Witten models. We explicitly construct the quantum corrections restoring higher-loop renormalizability for examples of integrable eta- and lambda-deformed sigma-models. We then consider the integrable GxG and GxG/H models and also construct a new class of integrable GxG/H models with abelian H. We also reformulate the lambda-models as sigma-models on a "tripled" GxGxG configuration space, where they become automatically renormalizable due to manifest global symmetries. In the limit when they become non-abelian dual (NAD) models, this suggests that the corresponding 'interpolating models' for NAD are also renormalizable, with 2-loop beta-functions matching the group/symmetric space models. We then present a new and different link between integrability and the RG flow in the context of sigma-models with 'local couplings' depending explicitly on 2d time. Such models are naturally obtained in the light-cone gauge in string theory, pointing to the possibility of a large, new class of solvable string models.
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II–induced cardiac, renal, and vascular injury
Creators: name: Wang, Zuofei
name: Kim, Hyung-Suk
name: Brown, Nancy J.
name: Luo, Pengcheng
name: Fogo, Agnes B.
name: Luther, James M.
name: Cohen, Samuel E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Angiotensin II causes cardiovascular injury in part by aldosterone-induced mineralocorticoid receptor activation, and it can also activate the mineralocorticoid receptor in the absence of aldosterone in vitro. Here we tested whether endogenous aldosterone contributes to angiotensin II/salt-induced cardiac, vascular, and renal injury by the mineralocorticoid receptor. Aldosterone synthase knockout mice and wild type littermates were treated with angiotensin II or vehicle plus the mineralocorticoid receptor antagonist spironolactone or regular diet while drinking 0.9- saline. Angiotensin II/salt caused hypertension in both the knockout and wild type mice; an effect significantly blunted in the knockout mice. Either genetic aldosterone deficiency or mineralocorticoid receptor antagonism reduced cardiac hypertrophy, aortic remodeling, and albuminuria, as well as cardiac, aortic, and renal plasminogen activator inhibitor-1 mRNA expression during angiotensin II treatment. Mineralocorticoid receptor antagonism reduced angiotensin II/salt-induced glomerular hypertrophy, but aldosterone deficiency did not. Combined mineralocorticoid receptor antagonism and aldosterone deficiency reduced blood urea nitrogen and restored nephrin immunoreactivity. Angiotensin II/salt also promoted glomerular injury through the mineralocorticoid receptor in the absence of aldosterone. Thus, mineralocorticoid antagonism may have protective effects in the kidney beyond aldosterone synthase inhibition.