cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Importância da Promoção dos Relacionamentos Positivos em Idade Pré-escolar
Creators: name: Saavedra, Rosa
name: Pinto, Mariana
name: Rodrigues, Letícia
name: Santos, Manuela
name: Silva, Cynthia
Publisher: name: Revista Interacções
Year: 2024

description: O Programa de Prevenção Hora de SER® – Sensibilizar e Educar para os Relacionamentos no Pré-Escolar, pretende introduzir a prevenção o mais precocemente possível, dotando as crianças e profissionais de ferramentas para a promoção de relacionamentos saudáveis. A capacidade de interagir de forma positiva com as outras pessoas não é inata. Os conhecimentos, competências e valores que facilitam o estabelecimento de relacionamentos positivos devem ser aprendidos precocemente e sedimentados ao longo do ciclo de vida. Competências como a cooperação e valores como o respeito são determinantes na manutenção de relacionamentos interpessoais positivos. A sua aprendizagem e treino devem ser fomentadas desde cedo, através da experiência e prática, no contacto com modelos de aprendizagem positivos. A família, a escola, outros contextos educativos e a comunidade são contextos com elevado potencial para o reconhecimento (e posterior reprodução) destes modelos. Neste artigo apresentamos o Programa Hora de SER®, na sua versão dirigida a crianças entre os 3 e os 6 anos, os módulos que o compõem e os principais resultados da avaliação de impacto social.
description: Revista Interacções, Vol. 20 N.º 69 (2024): Educação. Cidadania. Violência(s)
Propagating Surface Plasmon Polaritons: Towards Applications for Remote-Excitation Surface Catalytic Reactions
Creators: name: Zhang, Zhenglong
name: Fang, Yurui
name: Wang, Wenhui
name: Chen, Li
name: Sun, Mengtao
Publisher: name: Weinheim : Wiley-VCH
Year: 2015
Subjects: subject: plasmonic waveguides
subject: remote excitation
subject: surface catalytic reactions
subject: surface-enhanced Raman scattering
subject: 500
subject: 600
subject: 624

description: Plasmonics is a well-established field, exploiting the interaction of light and metals at the nanoscale; with the help of surface plasmon polaritons, remote-excitation can also be observed by using silver or gold plasmonic waveguides. Recently, plasmonic catalysis was established as a new exciting platform for heterogeneous catalytic reactions. Recent reports present remote-excitation surface catalytic reactions as a route to enhance the rate of chemical reactions, and offer a pathway to control surface catalytic reactions. In this review, we focus on recent advanced reports on silver plasmonic waveguide for remote-excitation surface catalytic reactions. First, the synthesis methods and characterization techniques of sivelr nanowire plasmonic waveguides are summarized, and the properties and physical mechanisms of plasmonic waveguides are presented in detail. Then, the applications of plasmonic waveguides including remote excitation fluorescence and SERS are introduced, and we focus on the field of remote-excitation surface catalytic reactions. Finally, forecasts are made for possible future applications for the remote-excitation surface catalysis by plasmonic waveguides in living cells.
Educação, Exclusão Escolar e Violência
Creators: name: Paiva De Carvalho, Guilherme
name: Da Frota, Amanda Oliveira
name: Souza, Karlla Christine Araújo
Publisher: name: Revista Interacções
Year: 2024

description: A presente pesquisa propôs como objetivo analisar a perspectiva de adolescentes em conflito com a lei a respeito da educação. O artigo analisa a forma como as desigualdades de classe, as relações de gênero e a discriminação racial moldam as experiências de adolescentes e jovens que cometem atos infracionais na sociedade brasileira. A investigação tomou como objeto de estudo a experiência de adolescentes e jovens que cumprem medida socioeducativa em meio aberto no município de Mossoró (RN), destacando a relação entre desigualdades de classe, exclusão escolar e violência a partir de uma perspectiva interseccional. Para tratar da temática proposta, são considerados os entrecruzamentos entre gênero, classe social, discriminação racial e cidadania restrita. Como metodologia de pesquisa optou-se pela narrativa de vida com a realização de entrevista semiestruturada com adolescentes e jovens acompanhados/as pelo Centro de Referência Especializado em Assistência Social (CREAS) de Mossoró (RN). O estudo mostra a importância de melhorias na qualidade da educação e de políticas públicas para prevenção da violência e o apoio de adolescentes e jovens em situação de vulnerabilidade.
description: Revista Interacções, Vol. 20 N.º 69 (2024): Educação. Cidadania. Violência(s)
Deformation behavior of metallic glass composites reinforced with shape memory nanowires studied via molecular dynamics simulations
Creators: name: Şopu, D.
name: Stoica, M.
name: Eckert, J.
Publisher: name: Melville, NY : American Inst. of Physics
Year: 2015
Subjects: subject: Composite materials
subject: Crystalline materials
subject: Deformation
subject: Glass
subject: Linear transformations
subject: 530

description: Molecular dynamics simulations indicate that the deformation behavior and mechanism of Cu64Zr36 composite structures reinforced with B2 CuZr nanowires are strongly influenced by the martensitic phase transformation and distribution of these crystalline precipitates. When nanowires are distributed in the glassy matrix along the deformation direction, a two-steps stress-induced martensitic phase transformation is observed. Since the martensitic transformation is driven by the elastic energy release, the strain localization behavior in the glassy matrix is strongly affected. Therefore, the composite materials reinforced with a crystalline phase, which shows stress-induced martensitic transformation, represent a route for controlling the properties of glassy materials. The authors acknowledge the financial support of the European Research Council under the ERC Advanced Grant INTELHYB (Grant No. ERC-2013-ADG-340025) and the German Science Foundation (DFG) under the Leibniz Program (Grant No. EC 111/26-1). A DAAD-PPP travel grant is also acknowledged. Computing time was made available at ZIH TU Dresden and IFW Dresden as well as by CSC Julich. The authors acknowledge Dr. Simon Pauly and Sergio Scudino for fruitful discussions.
Upgrading pasta wastes through lactic acid fermentations
Creators: name: López-Gómez, José Pablo
name: Unger, Peter
name: Schneider, Roland
name: Pierrard, Marie-Aline
name: Venus, Joachim
Publisher: name: Amsterdam : Elsevier
Year: 2022
Subjects: subject: Bacillus coagulans
subject: Pilot scale
subject: Enzymatic hydrolysis
subject: Food waste
subject: Circular bioeconomy
subject: 630
subject: 640
subject: 660

description: During its production process, every kilogram of pasta manufactured generates about 23 g of pasta wastes (PW). Considering the global pasta production, there are about 376 kilotonnes of PW produced every year. In this work, PW were characterised and used as the substrate in lactic acid (LA) fermentations. Enzymatic hydrolysis of 200 g/L of PW allowed for the liberation of sugars with a yield 0.81 gs/gdryPW. After the screening of several B. coagulans, the strain A559 was selected for experiments at the lab and pilot scales. Two fermentation modes were tested during lab scale experiments namely, simultaneous saccharification and fermentation and sequential hydrolysis and fermentation with the latter showing higher yields. The process was scaled up to 50 L where a LA concentration of 47.67 g/L and yield of 0.67 gLA/gdrydPW were achieved.
Kinematic origin for near-zero energy structures in mid-IR strong field ionization
Creators: name: Pisanty, Emilio
name: Ivanov, Misha
Publisher: name: Bristol : IOP Publ.
Year: 2016
Subjects: subject: low-energy structures
subject: near-zero energy structures
subject: photoionization
subject: strong-field physics
subject: tunnel ionization
subject: zero-energy structures
subject: 530

description: We propose and discuss a kinematic mechanism underlying the recently discovered 'near-zero energy structure' in the photoionization of atoms in strong mid-infrared laser fields, based on trajectories which revisit the ion at low velocities exactly analogous to the series responsible for low-energy structures. The different scaling of the new series, as $E\sim {I}_{p}^{2}/{U}_{p}$, suggests that the near-zero energy structure can be lifted to higher energies, where it can be better resolved and studied, using harder targets with higher ionization potential.
Synthesis of surfactant-free Cu–Pt dendritic heterostructures with highly electrocatalytic performance for methanol oxidation reaction
Creators: name: Kang, Shendong
name: Gao, Guanhui
name: Xie, Xiaobin
name: Shibayama, Tamaki
name: Lei, Yanhua
name: Wang, Yan
name: Cai, Lintao
Publisher: name: London [u.a.] : Taylor & Francis
Year: 2016
Subjects: subject: Cu–Pt coral-like nanoparticles
subject: Cu–Pt dendritic spherical heterostructures
subject: electrocatalytic property
subject: methanol oxidation reaction
subject: 530
subject: 600
subject: 670

description: A facile and free surfactant strategy is explored to synthesize Cu–Pt bimetallic nano-heterostructures with dendritic exterior. For comparison, the Cu–Pt coral-like nanoparticles are fabricated by using CTAC as a surfactant. The well-designed Cu–Pt dendritic spherical heterostructures exhibit superior enhanced electrocatalytic activity and stability toward methanol oxidation reaction in alkaline media, compared to the Cu–Pt coral-like nanoparticles and the commercial Pt/C, respectively. The advanced technique for fabricating Cu–Pt dendritic spherical heterostructures could pave a way to pursue low-cost Pt-based catalysts, maintaining highly promoted electrocatalytic performance and durability.
Prevalência, Legitimação e Prevenção da Violência de Namoro nas/os Jovens
Creators: name: Pacheco, Margarida
name: Dias, Ana Teresa
name: Borges, Bianca
name: Pinto, Beatriz
name: Maia, Margarida
Publisher: name: Revista Interacções
Year: 2024

description: A violência de género é uma problemática social, de saúde pública e é um atentado aos Direitos Humanos, sendo que os  programas de prevenção primária nas escolas são a forma mais eficaz para combater e eliminar esta forma de violência. Em 2004, a UMAR - União de Mulheres Alternativa e Resposta - criou um programa de prevenção primária da violência de género, financiado desde 2014 pelo governo português intitulado ART´THEMIS+.  Este programa, holístico e sistemático, intervém com crianças e jovens desde o jardim de infância até ao ensino secundário/profissional, abordando diversas temáticas, entre as quais Direitos Humanos, estereótipos, preconceitos, discriminações e violência(s). Uma das formas de violência de género que tem preocupado as ONG´s e as instituições políticas é a violência nas relações de namoro na adolescência. Neste sentido, o Projeto ART´THEMIS+ tem vindo a realizar um estudo a nível nacional, com jovens do 3º ciclo do ensino básico e do secundário/profissional do ensino português, anualmente, desde 2017 intitulado “Violência no Namoro em Portugal: vitimação e conceções juvenis”. Os objetivos deste estudo são compreender os indicadores de legitimação e de vitimação das/os jovens em Portugal. Os resultados do estudo nacional sobre a violência no namoro da UMAR de 2024, demonstram que 68,1% das/os participantes não considera violência no namoro, pelo menos, 1 dos 15 comportamentos abusivos referidos no estudo. Por sua vez, 63% das/os jovens inquiridas/os reportou ter experienciado, pelo menos, 1 dos 15 indicadores de vitimação questionados. Os resultados deste estudo demonstram também que as raparigas são mais vitimas de violência no namoro, enquanto, os rapazes legitimam mais esta forma de violência, o que realça a importância dos programas de prevenção de violência de género com jovens para se refletir as dinâmicas, comportamentos e conceções de género presentes nas relações de intimidade.
description: Revista Interacções, Vol. 20 N.º 69 (2024): Educação. Cidadania. Violência(s)
Pathogenesis of Distal Symmetrical Polyneuropathy in Diabetes.
Creators: name: Smith, Sasha
name: Normahani, Pasha
name: Lane, Tristan
name: Hohenschurz-Schmidt, David
name: Oliver, Nick
name: Davies, Alun Huw
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: diabetes
diabetic neuropathy
distal symmetrical polyneuropathy
neuropathic pain
pathogenesis
hyperglycemia
central nervous system
glycemic control
pain management
spinal cord stimulation

description: Distal symmetrical polyneuropathy (DSPN) is a serious complication of diabetes associated with significant disability and mortality. Although more than 50% of people with diabetes develop DSPN, its pathogenesis is still relatively unknown. This lack of understanding has limited the development of novel disease-modifying therapies and left the reasons for failed therapies uncertain, which is critical given that current management strategies often fail to achieve long-term efficacy. In this article, the pathogenesis of DSPN is reviewed, covering pathogenic changes in the peripheral nervous system, microvasculature and central nervous system (CNS). Furthermore, the successes and limitations of current therapies are discussed, and potential therapeutic targets are proposed. Recent findings on its pathogenesis have called the definition of DSPN into question and transformed the disease model, paving the way for new research prospects.
Educação Mediática e Submundo da Cibercultura
Creators: name: Magossi, Priscila
Publisher: name: Revista Interacções
Year: 2024

description: O presente trabalho concentra-se em expor as práticas predatórias do "submundo da cibercultura" (plataformas digitais relacionadas à pornografia, webcamming e vendas de "packs" eróticos. A discussão debruça-se sobre a influência da publicidade dessas empresas no enfeitiçamento (Morin, 1986) de meninas e mulheres e na zona de conforto e invisibilidade dos tiranos (Chauí, 1976) que controlam este mercado. Objetiva-se fomentar o debate sobre a necessidade de responsabilização do sistema de capatazia (mandantes ocultos, influenciadoras digitais e coaches). A metodologia refere-se a uma pesquisa de ordem qualitativa, a natureza dos dados é descritiva, com foco nos padrões identificados pela pesquisa netnográfica (análise de contrato de prestação de serviços e mapeamento dos atores sociais do submundo) em associação ao quadro teórico (teorias críticas da comunicação e da cibercultura). Os resultados apontam para a possibilidade de contenção (de parte) da violência digital causada pela guerra de narrativas digitais (desinformação e fake news) a partir da ação coletiva de educadores, pesquisadores, Poder Judiciário e sociedade civil. Contribui-se, assim, para a luta contra a violência cibercultural contra meninas e mulheres por meio da educação mediática.
description: Revista Interacções, Vol. 20 N.º 69 (2024): Educação. Cidadania. Violência(s)
The Gr64 cluster of gustatory receptors promotes survival and proteostasis of epithelial cells in Drosophila.
Creators: name: Baumgartner, Michael E
name: Mastrogiannopoulos, Alex
name: Kucinski, Iwo
name: Langton, Paul F
name: Piddini, Eugenia
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: subject: Discovery Report
subject: Biology and life sciences
subject: Research and analysis methods
subject: Social sciences
subject: FOS: Social sciences

description: Gustatory Receptor 64 (Gr64) genes are a cluster of 6 neuronally expressed receptors involved in sweet taste sensation in Drosophila melanogaster. Gr64s modulate calcium signalling and excitatory responses to several different sugars. Here, we discover an unexpected nonneuronal function of Gr64 receptors and show that they promote proteostasis in epithelial cells affected by proteotoxic stress. Using heterozygous mutations in ribosome proteins (Rp), which have recently been shown to induce proteotoxic stress and protein aggregates in cells, we show that Rp/+ cells in Drosophila imaginal discs up-regulate expression of the entire Gr64 cluster and depend on these receptors for survival. We further show that loss of Gr64 in Rp/+ cells exacerbates stress pathway activation and proteotoxic stress by negatively affecting autophagy and proteasome function. This work identifies a noncanonical role in proteostasis maintenance for a family of gustatory receptors known for their function in neuronal sensation.
Competência Digital Docente a Partir do Ensino Remoto de Emergência
Creators: name: Zimmer Sarzi, Luana
name: Karine Ramos, Daniela
name: Rocha Lucas, Margarida
Publisher: name: Revista Interacções
Year: 2024

description: As adaptações necessárias às práticas docentes durante a pandemia mobilizaram as competências digitais. Diante disso, conduziu-se uma  revisão de escopo com o objetivo mapear os estudos sobre Competência Digital desenvolvidos com professores que atuaram durante o Ensino Remoto de Emergência (ERE) durante a pandemia de covid-19. A revisão foi realizada nas bases de dados: Scopus, Web of Science e Doaj. Inicialmente foram encontrados 271 registros, após a seleção criteriosa com base em critérios de inclusão previamente estabelecidos foram analisados 11 estudos. Os dados extraídos nos textos foram organizados em categorias relacionadas à metodologia das pesquisas e a Competência Digital. Dentre os principais resultados destacam-se os estudos que apresentam ações, práticas e experiências vivenciadas pelos participantes durante o ERE e que indicam o aprimoramento de sua Competência Digital. Além disso, muitos estudos apontam a necessidade de aprimorar os processos de formação docente para o desenvolvimento dessa competência pelos educadores, principalmente após o período de atuação no ERE.
description: Revista Interacções, Vol. 20 N.º 67 (2024): Chamada de artigos: Edição em fluxo contínuo
Too many cooks
Creators: name: Horne, Alex
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Original Research
Indeterminacy and Underdetermination
Indeterminacy
Underdetermination
Idealization
Rationality
Subjectivism

description: Funder: Gates Cambridge Trust; doi: http://dx.doi.org/10.13039/501100005370
description: AbstractThe existing literature on the rational underdetermination problem often construes it as one resulting from the ubiquity of objective values. It is therefore sometimes argued that subjectivists need not be troubled by the underdetermination problem. But on closer examination, it turns out, they should. Or so I will argue. The task of the first half of this paper is explaining why. The task of the second half is finding a subjectivist solution the rational underdetermination problem. The basic problem, I argue, is as follows. Idealizing subjectivism generates too many ideal selves to deliver determinate or commensurable options regarding what non-ideal deliberating agents ought to do. My solution: these idealized options should be assessed from the only perspective we can, in fact, occupy, namely, that of our non-ideal, actual selves. Deciding what to do therefore becomes, in part, an exercise in deciding who to be. But one might now worry this just moves the arbitrariness bump in the rug. Privileging the perspective of our actual self seems contrary to the rationale for idealizing in the first place. I consider two solutions to the problem, one democratic, the other modelled on trusteeship. In the end, I argue, our actual self has complete freedom to choose the ideal self it grants rational authority. In the final part of the paper, I present my positive proposal as a solution to the underdetermination problem confronting the idealizing subjectivist and then argue that, so understood, this account vindicates a tidied-up version of how some reflective people already do deliberate in their everyday lives. This, in turn, suggests that a decision-procedure closely connected to the account is both possible (because actual) and attractive.
Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study.
Creators: name: Åkerlund, Cecilia AI
name: Holst, Anders
name: Stocchetti, Nino
name: Steyerberg, Ewout W
name: Menon, David K
name: Ercole, Ari
name: Nelson, David W
name: CENTER-TBI Participants And Investigators
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research
NCT02210221
NCT
Personalized medicine in the ICU
Traumatic brain injury
Endotypes
Intensive care unit
Critical care
Unsupervised clustering
Machine learning

description: Funder: Karolinska Institute
description: BACKGROUND: While the Glasgow coma scale (GCS) is one of the strongest outcome predictors, the current classification of traumatic brain injury (TBI) as 'mild', 'moderate' or 'severe' based on this fails to capture enormous heterogeneity in pathophysiology and treatment response. We hypothesized that data-driven characterization of TBI could identify distinct endotypes and give mechanistic insights. METHODS: We developed an unsupervised statistical clustering model based on a mixture of probabilistic graphs for presentation (< 24 h) demographic, clinical, physiological, laboratory and imaging data to identify subgroups of TBI patients admitted to the intensive care unit in the CENTER-TBI dataset (N = 1,728). A cluster similarity index was used for robust determination of optimal cluster number. Mutual information was used to quantify feature importance and for cluster interpretation. RESULTS: Six stable endotypes were identified with distinct GCS and composite systemic metabolic stress profiles, distinguished by GCS, blood lactate, oxygen saturation, serum creatinine, glucose, base excess, pH, arterial partial pressure of carbon dioxide, and body temperature. Notably, a cluster with 'moderate' TBI (by traditional classification) and deranged metabolic profile, had a worse outcome than a cluster with 'severe' GCS and a normal metabolic profile. Addition of cluster labels significantly improved the prognostic precision of the IMPACT (International Mission for Prognosis and Analysis of Clinical trials in TBI) extended model, for prediction of both unfavourable outcome and mortality (both p < 0.001). CONCLUSIONS: Six stable and clinically distinct TBI endotypes were identified by probabilistic unsupervised clustering. In addition to presenting neurology, a profile of biochemical derangement was found to be an important distinguishing feature that was both biologically plausible and associated with outcome. Our work motivates refining current TBI classifications with factors describing metabolic stress. Such data-driven clusters suggest TBI endotypes that merit investigation to identify bespoke treatment strategies to improve care. Trial registration The core study was registered with ClinicalTrials.gov, number NCT02210221 , registered on August 06, 2014, with Resource Identification Portal (RRID: SCR_015582).
Experiences of 'traditional' and 'one-stop' MRI-based prostate cancer diagnostic pathways in England: a qualitative study with patients and GPs.
Creators: name: Merriel, Samuel William David
name: Archer, Stephanie
name: Forster, Alice S
name: Eldred-Evans, David
name: McGrath, John
name: Ahmed, Hashim Uddin
name: Hamilton, Willie
name: Walter, Fiona
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Qualitative research
1506
1725
primary care
qualitative research
prostate disease
urological tumours
magnetic resonance imaging

description: OBJECTIVES: This study aimed to understand and explore patient and general practitioner (GP) experiences of 'traditional' and 'one-stop' prostate cancer diagnostic pathways in England. DESIGN: Qualitative study using semi-structured interviews, analysed using inductive thematic analysis SETTING: Patients were recruited from National Health Service (NHS) Trusts in London and in Devon; GPs were recruited via National Institute for Health Research (NIHR) Clinical Research Networks. Interviews were conducted in person or via telephone. PARTICIPANTS: Patients who had undergone a MRI scan of the prostate as part of their diagnostic work-up for possible prostate cancer, and GPs who had referred at least one patient for possible prostate cancer in the preceding 12 months. RESULTS: 22 patients (aged 47-80 years) and 10 GPs (6 female, aged 38-58 years) were interviewed. Patients described three key themes: cancer beliefs in relation to patient's attitudes towards prostate cancer; communication with their GP and specialist having a significant impact on experience of the pathway and pathway experience being influenced by appointment and test burden. GP interview themes included: the challenges of dealing with imperfect information in the current pathway; managing uncertainty in identifying patients with possible prostate cancer and sharing this uncertainty with them, and other social, cultural and personal contextual influences. CONCLUSIONS: Patients and GPs reported a range of experiences and views of the current prostate cancer diagnostic pathways in England. Patients valued 'one-stop' pathways integrating prostate MRI and diagnostic consultations with specialists over the more traditional approach of several hospital appointments. GPs remain uncertain how best to identify patients needing referral for urgent prostate cancer testing due to the lack of accurate triage and risk assessment strategies.
O Desenvolvimento do Self e o Adolescer em Contexto de Isolamento Social
Creators: name: Conceição, Verônica Alves Dos Santos
name: Da Silva, Márcio Santana
name: Azevedo, Leandro Ribeiro
Publisher: name: Revista Interacções
Year: 2024

description: O conceito de self envolve a capacidade de um ator social assumir a consciência de si mesmo na relação de trocas simbólicas com o meio social em que se insere, sendo a adolescência a fase do desenvolvimento em que a interação simbólica acontece com mais intensidade. O que se busca como objetivo é analisar as consequências sobre o sistema do self de adolescentes quando o contexto social sofre mudanças repentinas e radicais, como as ocorridas entre 2020 e 2023 com a adoção do isolamento social como medida preventiva contra a COVID 19. O estudo constitui uma revisão sistemática de literatura seguindo os parâmetros da lista Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA).Utilizou-se o PICO como estratégia se elegibilidade dos estudos selecionados em cinco fontes de dados, sendo PsycInfo, Scopus, Scielo, Pubmed e Pepsic com delimitação temporal nos anos 2020 a 2023. Foram identificados noventa e três estudos e, após critérios de inclusão e exclusão, 7 artigos foram analisados. Constata-se a ausência de estudos que tematizam o desenvolvimento do self em adolescentes durante a pandemia do COVID-19.
description: Revista Interacções, Vol. 20 N.º 67 (2024): Chamada de artigos: Edição em fluxo contínuo
Differentiated function and localisation of SPO11-1 and PRD3 on the chromosome axis during meiotic DSB formation in Arabidopsis thaliana.
Creators: name: Lambing, Christophe
name: Kuo, Pallas
name: Kim, Jaeil
name: Osman, Kim
name: Whitbread, Amy Leanne
name: Yang, Jianhua
name: Choi, Kyuha
name: Franklin, F Chris H
name: Henderson, Ian
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research Article
Research and analysis methods
Biology and life sciences

description: During meiosis, DNA double-strand breaks (DSBs) occur throughout the genome, a subset of which are repaired to form reciprocal crossovers between chromosomes. Crossovers are essential to ensure balanced chromosome segregation and to create new combinations of genetic variation. Meiotic DSBs are formed by a topoisomerase-VI-like complex, containing catalytic (e.g. SPO11) proteins and auxiliary (e.g. PRD3) proteins. Meiotic DSBs are formed in chromatin loops tethered to a linear chromosome axis, but the interrelationship between DSB-promoting factors and the axis is not fully understood. Here, we study the localisation of SPO11-1 and PRD3 during meiosis, and investigate their respective functions in relation to the chromosome axis. Using immunocytogenetics, we observed that the localisation of SPO11-1 overlaps relatively weakly with the chromosome axis and RAD51, a marker of meiotic DSBs, and that SPO11-1 recruitment to chromatin is genetically independent of the axis. In contrast, PRD3 localisation correlates more strongly with RAD51 and the chromosome axis. This indicates that PRD3 likely forms a functional link between SPO11-1 and the chromosome axis to promote meiotic DSB formation. We also uncovered a new function of SPO11-1 in the nucleation of the synaptonemal complex protein ZYP1. We demonstrate that chromosome co-alignment associated with ZYP1 deposition can occur in the absence of DSBs, and is dependent on SPO11-1, but not PRD3. Lastly, we show that the progression of meiosis is influenced by the presence of aberrant chromosomal connections, but not by the absence of DSBs or synapsis. Altogether, our study provides mechanistic insights into the control of meiotic DSB formation and reveals diverse functional interactions between SPO11-1, PRD3 and the chromosome axis.
A comprehensive study on active mixer performance using liquid metal droplets: an experimental approach
Creators: name: Jafarpour, Ali Mohammad
name: Khosroshahi, Alireza Rostamzadeh
name: Hanifi, Masoud
name: Moghanlou, Farhad Sadegh
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: In this experimental study, we delve into the performance of an active mixer that utilizes liquid metal droplets. Our mixer configuration follows an innovative Y-type design, where two liquid metal-based pumping mechanisms operate within the minichannel inlet branches. By applying alternating current voltage to both sides of the liquid metal, we induce a surface tension gradient, propelling the fluid from the reservoirs toward the minichannel. Notably, the two entering liquids are distinctly colored, allowing us to quantify mixing using a Mixing Index (MI) definition and image processing techniques. Our investigation centers on four key variables governing mixer performance: applied voltage, liquid metal droplet diameter, input angle between the branches, and minichannel width. Given the experimental nature of our research, we employ a central composite design method within the framework of design of experiments (DoE). From our obtained experimental results, we establish correlations between MI and the other variables. Our examination of the four mentioned parameters revealed that liquid metal droplet diameter exerts the most significant influence on the mixing index. Following this, in descending order of impact, we find applied voltage, input angle, and channel width. In the optimal dimensions of our mixer, we achieve a remarkable maximum MI of 0.867.
Redes de Apoio Social e Enfrentamento às Violências Contra as Mulheres
Creators: name: Xavier, Natacha Farias
name: Marcelo, Carolina Marinho
name: Ximenes, Verônica Morais
Publisher: name: Revista Interacções
Year: 2024

description: A violência contra a mulher tem cada vez mais apresentado dados crescentes e que preocupam, assim, é imperativo revisar as estratégias de enfrentamento e promover espaços de debate e construção de alternativas que visem fortalecer as mulheres para que estas possam ampliar suas redes de apoio e proteção, uma vez que violência alguma se enfrenta de maneira isolada. Discutir violência contra as mulheres em nível acadêmico, é tarefa complexa e demanda dos facilitadores um manejo dinâmico e ético-político em sua ação. Dessa forma, objetivamos através desse estudo, discutir os resultados da experiência de um curso de extensão universitária sobre redes de apoio social e enfrentamento às violências contra as mulheres pautadas no referencial teórico da Psicologia social e da Teoria Feminista Interseccional. Como percurso metodológico, optou-se pelo modelo qualitativo em caráter descritivo, através do relato de experiência da condução de um curso de extensão. Dividimos os resultados e discussão em três tópicos: o planejamento do curso, onde apontamos como foi elaborada a metodologia de execução do curso; um tópico sobre a categoria rede de apoio social como estratégia de enfrentamento coletivo à violência contra a mulher e o terceiro tópicos discutimos o impacto do curso na realidade das participantes. Esse percurso nos trouxe elementos importantes acerca das práticas de ensino e debate sobre violência contra a mulher, e destacamos a educação como uma das componentes necessárias para tensionar o fomento de políticas de enfrentamento às diversas violências.
description: Revista Interacções, Vol. 20 N.º 69 (2024): Educação. Cidadania. Violência(s)
Effective application of green nano adsorbent on the removal of carbofuran from wastewater
Creators: name: Aboeleneen, N. M.
name: AbdelMonem, Nabil M.
name: Atef, Riham
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: In this study, carbofuran (CF) was eliminated from wastewater using pomegranate peel nano adsorbent (PPNA). Infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and Brunauer–Emmett–Teller (BET) before and after adsorption were used to assess the process efficiency. BET demonstrated that the PPNA has a specific surface area of 356.5 m2/g. The PPNA was tested under some environmental factors, such as contact time, concentration, adsorbent dose, temperature, and pH. Experimental work was done within the range of 10–50 mg/l initial concentration and the best biosorption capacities were found at 30 min contact time, 0.7 g adsorbent dose, 25 °C, and pH 2. The Freundlich isotherm was the best-fitting isotherm model. The pseudo-second-order model provided the best fit to the process kinetics and indicated that the intra-particle diffusion stage is the rate-limiting step for the process. The study of thermodynamics showed that carbofuran adsorption on PPNA was physisorption (ΔG = −3.2334 kJ/mol) and spontaneous at high temperatures (ΔH = 22.2058 kJ/mol, ΔS = 85.0355 J/mol K). Design of a single-stage batch adsorber for the adsorption of CF from aqueous liquors using PPNA was also done.
Calcific tendinopathy of the pectoralis major mimicking bony metastasis
Creators: name: Lam, Luthan
Publisher: name: EURORAD
Year: 2018
Subjects: subject: Musculoskeletal bone
subject: CT
subject: Digital radiography
subject: MR
subject: Nuclear medicine conventional
subject: Diagnostic procedure
subject: Neoplasia

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 77 years
description: Clinical History: A 77-year old male patient with newly diagnosed prostate cancer attends for a Tc-99m bone scan, which lead to the suspicion of humeral metastasis.  The patient was asymptomatic, with a mildly raised PSA and had a normal bone profile. Final Diagnosis: Calcific tendinopathy of the pectoralis major tendon
Odontogenic myxoma of mandible
Creators: name: KUMARI, LATA
Publisher: name: EURORAD
Year: 2018
Subjects: subject: Head and neck
subject: CT
subject: MR
subject: MR-Diffusion/Perfusion
subject: Computer Applications-3D
subject: Diagnostic procedure
subject: Neoplasia

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 37 years
description: Clinical History: A 37-year-old male presented with the complaint of swelling over right side of mandible since 1 year. Final Diagnosis: Odontogenic myxoma of Mandible.
Part 1
Publisher: name: Columbia University
Year: 2021

description: Panelists are [Fred?] Martin, administrator at Malcom X Shabazz [high school], [?] Giles, Harriet Tubman School, Robert Bascomb, Clinton Street School, [Muminina?] Jalia [Woods?], Afrikan Free School, Brother Gibson from Central High School
Developing Data Reduction Pipelines for IFU Data
Creators: name: Cardiel, Nicolás
name: Pascual, Sergio
name: Gallego, Jesús
name: Castillo-Morales, África
name: Gil de Paz, Armando
name: Sánchez-Blázquez, Patricia
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Astronomy
subject: Software

description: The UCM group of Extragalactic Astrophysics and Astronomical Instrumentation (GUAIX) is involved in the development of the data reduction pipelines of two future Integral Field Unit (IFU) instruments: FRIDA for the Gran Telescopio Canarias (GTC) and TARSIS for the 3.5m telescope of the Calar Alto Observatory. For this reason we are developing basic functionality for the reduction of integral field spectroscopic observations in Python that can be useful in the development of the corresponding data reduction pipelines: fridadrp and tarsisdrp. Both packages will use the same user interface, numina, whose versatility has already been demonstrated in the development of the data processing chains for GTC's EMIR and MEGARA instruments.

As a first step, we have created fridadrp-ifu_simulator,which allows the generation of simulated FRIDA IFU images to begin the development and testing of reduction recipes. This software is still under development.
description: Grant PID2022-138621NB-I00 funded by MCIN/AEI/ 10.13039/501100011033/ and by “ERDF A way of making Europe”.

Project PR47/21 TAU-CM PRTR-CM
Guidelines to foster building with wood. BASAJAUN Public report D1.3
Creators: name: Leszczyszyn, Ewa
name: Augustyniak, Dobrochna
name: Bidzińska,, Gabriela
name: Noskowiak, Andrzej
name: Heräjärvi, Henrik
name: Verkasalo, Erkki
name: Lanvin, Jean-Denis
name: Blanquet, Ilona
name: Kouyoumji, Jean-Luc
name: Wahlström, Margareta
name: García Jaca, Javier
Publisher: name: ITD, LUKE, FCBA, VTT, TEC
Year: 2021

description: Wooden construction has great development potential in Europe and in the world. It is based on a renewable and inexhaustible source of raw material, which is wood. However, this potential is still not fully exploited, while broader use of wood in construction could bring significant benefits, not only in environmental but also in social and economic terms. Innovative technologies that allow rapid construction of energy-efficient wooden buildings, including multi-storey, are a great opportunity for wooden construction development. Therefore, it is important to foster building with wood, indicate the opportunities it brings and its benefits, but also take into account the barriers limiting its development. The aim of the report was to prepare guidelines for fostering wooden building and to indicate conditions of its development. The report covered:
▪ indication of major development opportunities for wooden construction in Europe and in the world, taking into account technical, political, economic and societal aspects,
▪ identification of significant barriers inhibiting the development of the use of wood in construction, including its weaknesses and threats in the technical, political, economic and societal context,
▪ assessment of the potential of using recycled wood in the construction sector, including estimating the potential supply of post-consumer wood waste and wood by-products,
▪ gathering examples of best practices in wood recycling in different countries based on case studies,
▪ basic characteristics of the regulatory framework and operational environment for recycled wooden products in chosen countries of the project partners,
▪ identification of key economic, social, environmental and technical benefits of using wood and wood products in construction.
description: BASAJAUN is a European innovation action about sustainable building with wood. The main objective is to demonstrate how wood construction chains can be optimized to foster both rural development and urban transformation whilst being connected with sustainable forest management in Europe. The consortium comprises 29 partners from 12 countries including 8 leading research and technology organizations, 3 universities, 15 companies and 4 other public and sectoral organizations. The project is coordinated by the Tecnalia Research and Innovation Foundation in Spain and has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no. 862942.
Investigating The Dynamic Performance Of Power Devices In Parallel Connection
Creators: name: Wei, Jixuan
Publisher: name: University of Leicester
Year: 2024
Subjects: Uncategorized

description: With the emergence of wind power, smart grids, electric vehicles and high-voltage inverters, high-power devices have become increasingly popular in industry. The efficiency and reliability of power devices in the design of high-power systems are critical, with the efficiency and reliability of high-power switching devices playing an essential role. Thus, before designing a converter, the switching transient of the semiconductor device must be analysed using a simulation tool, typically utilising physical, behavioral, or analytical models. In this thesis, an analytical model of devices in parallel connection was proposed as a method of understanding the working principle of the internal devices of the module and simulating the current sharing behavior, with the impact of device and circuit mismatch on current sharing behavior of SiC MOSFET in parallel connection being investigated. Additionally, analytical models were applied to SiC/Si hybrid switches, combining the advantages of Si IGBT and SiC MOSFET, examining the static, dynamic, and crosstalk behavior of hybrid switches and determining the relationship between switching loss and delay time. A double pulse test platform was established to verify the model, the model showcasing good agreement with the experimental while maintaining a high simulation speed.
Developing Data Reduction Pipelines for IFU Data
Creators: name: Cardiel, Nicolás
name: Sergio, Pascual
name: Gallego, Jesús
name: Castillo-Morales, África
name: Gil de Paz, Armando
name: Sánchez-Blázquez, Patricia
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Astronomy
subject: Software

description: The UCM group of Extragalactic Astrophysics and Astronomical Instrumentation (GUAIX) is involved in the development of the data reduction pipelines of two future Integral Field Unit (IFU) instruments: FRIDA for the Gran Telescopio Canarias (GTC) and TARSIS for the 3.5m telescope of the Calar Alto Observatory. For this reason we are developing basic functionality for the reduction of integral field spectroscopic observations in Python that can be useful in the development of the corresponding data reduction pipelines: fridadrp and tarsisdrp. Both packages will use the same user interface, numina, whose versatility has already been demonstrated in the development of the data processing chains for GTC's EMIR and MEGARA instruments.

As a first step, we have created fridadrp-ifu_simulator,which allows the generation of simulated FRIDA IFU images to begin the development and testing of reduction recipes. This software is still under development.
description: Grant PID2022-138621NB-I00 funded by MCIN/AEI/ 10.13039/501100011033/ and by “ERDF A way of making Europe”.
title: Dynamics of melting solids using SPH
Creators: name: Blank, Michael
Publisher: name: Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
Year: 2017
Subjects: subject: computational fluid mechanics, SPH, melting processes, surface tension

description: In this thesis a meshless multiphysics simulation method based on the smoothed particle hydrodynamics (SPH) method is introduced and is applied to the simulation of dynamic melting processes. For this purpose, models for separate physical phenomena available in an academic SPH code were separately validated. These models include implicit viscous force computation for highly viscous flows and heat transfer for bodies with complex shaped free surfaces. Subsequently, a model for modifying the specific heat capacity which approximates the latent heat over a temperature interval around the melting temperature is implemented. In order to validate the viscosity model used, the coalescence of agglomerate chains with three or six primary spheres under the influence of surface tension is simulated. The time required to obtain a spherical shape through a viscous flow assumption is seen to be less in the case of SPH than that simulated by a surface area minimization algorithm. This could be due to inertial and hydrodynamic effects. The heat transport is then validated with two-dimensional analytical solutions of the heat conduction equation for different boundary conditions. The order of accuracy for this heat transfer model is shown to be more than first order. To determine the accuracy of the moving phase boundary position, an analytical solution of the two-dimensional Neumann problem is used and compared with the corresponding SPH results. The determined average error is between 3.67% and 0.60% as a function of the number of interpolation points and the boundary conditions used. The validated models of the viscosity, the heat conduction and the latent heat are then coupled to models for surface tension as well as rigid body interactions which are already part of the code. Thus, the multiphysics model obtained is used for the simulation of different morphologies with a heat of fusion of 1 J/kg, 1 kJ/kg and 100 kJ/kg, respectively. The surface evolution of complex shaped bodies melting at time scales comparable to the fluid flow time scales is shown to be a highly non-linear phenomena deviating considerably from viscous sintering models in literature. The usefulness of this simulation method for optimizing industrial process designs is thus demonstrated.
Additional file 1 of Effectiveness of the online Acceptance and Commitment Therapy intervention “Embrace Pain” for cancer survivors with chronic painful chemotherapy-induced peripheral neuropathy: study protocol for a randomized controlled trial
Creators: name: van de Graaf, Daniëlle L.
name: Mols, Floortje
name: Trompetter, Hester R.
name: van der Lee, Marije L.
name: Schreurs, Karlein M. G.
name: Børøsund, Elin
name: Nes, Lise Solberg
name: Smeets, Tom
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1: Subject information for participation in medicalscientific research.
ทวิลักษณ์ในงานภาพกับลายลักษณ์อักษร ที่ซึ่งจินตนาการและสุนทรียภาพอุบัติพร้อม
Creators: name: ศิริชัย ศิริกายะ และกฤษณ์ ทองเลิศ
Publisher: name: สถาบันวิศวการพิมพ์ มหาวิทยาลัยสยาม
Year: 2560
Subjects: ทวิลักษณ์, งานภาพกับลายลักษณ์อักษร, จินตนาการ, สุนทรียภาพ

description: นิเทศสยามปริทัศน์, 16, 21, 7-10
การพัฒนาสื่อวิดีโออินโฟกราฟิกแบบมีปฏิสัมพันธ์บนเครือข่ายสังคม  เรื่อง กระบวนการผลิตรายการโทรทัศน์ประเภทบันเทิง บริษัท โมโน บรอดคาซท์ จำกัด
Creators: name: พรปภัสสร ปริญชาญกล; กุลธิดา ธรรมวิภัชน์; โสพล มีเจริญ; ถกนวรรณ น้อยปุก; ศรุตา รัตนชีวกร; และณพวิทย์ พานิชปฐม
Publisher: name: สถาบันวิศวการพิมพ์ มหาวิทยาลัยสยาม
Year: 2560
Subjects: วิดีโออินโฟกราฟิก, ปฏิสัมพันธ์บนเครือข่ายสังคม, กระบวนการผลิตรายการโทรทัศน์ประเภทบันเทิง

description: นิเทศสยามปริทัศน์, 16, 21, 11 . 20
Additional file 2 of Effectiveness of the online Acceptance and Commitment Therapy intervention “Embrace Pain” for cancer survivors with chronic painful chemotherapy-induced peripheral neuropathy: study protocol for a randomized controlled trial
Creators: name: van de Graaf, Daniëlle L.
name: Mols, Floortje
name: Trompetter, Hester R.
name: van der Lee, Marije L.
name: Schreurs, Karlein M. G.
name: Børøsund, Elin
name: Nes, Lise Solberg
name: Smeets, Tom
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2: Appendix E. All items from the World Health Organization Trial Registration Data Set.