cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Membangun Kemampuan Berfikir Matematika Tingkat Tinggi Melalui Pendekatan Induktif, Deduktif danInduktif-Deduktif Dalam Pembelajaran Matematika
Creators: name: Winarso, Widodo
Publisher: name: figshare
Year: 2016
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: Pendidikan diera globalitas memberikan tantangan bagi pendidik untuk meningkatkan kualitas pembelajaran. Upaya yang perlu dilakukan salah satunya yaitu perubahan cara mengajar. Gaya mengajar yang mengabaikan kreatifitas peserta didik dapat disinyalir sebagai setagnannya mutu pencapaian tujuan pembelajaran. Oleh karena itu, pembelajaran yang baik apabila pendidik dapat berkreasi dalam mengimplementasikan pendeketan pembelajaran; alasan dan perlunya perubahan pendekatan pembelajaran matematika dari cara tradisional ke arah yang lebih inovatif dan sesuai dengan tuntutan zaman yaitu pendekatan pembelajaran yang dapat menunjang pencapaian lima tujuan pelajaran matematika; serta pembelajaran yang lebih fokus pada pemecahan masalah, membanun krativitas belajar dan dapat memfasilitasi para peserta didik untuk mengkontrusi pengetahuan matematika. Kegiatan pembelajaran dapat berjalan dengan baik dan sesuai dengan tututan kurikulum 2013, apabila pendidik menyajikan materi ajar dengan menerapkan pendekatan pembelajaran yang berpusat pada peserta didik. Sekiranya penting bagi para pendidik untuk merubah strategi pembelajarannya. Misalnya pembelajaran dengan pendekatan induktif, deduktif dan kolaburasi dari induktif-deduktif. Dengan demikian dapat dimaknai bahwa pendekatan pembelajaran dapat digunakan sebagai acuan pada kegiatan perancangan kegiatan yang sistematik dalam mengkomunikasikan isi pelajaran kepada peserta didik untuk meningkatkan kemampuan berfikir matematika tingkat tinggi siswa.
New planar trans-copper(II) β-dithioester chelate complexes: Synthesis, characterization, anticancer activity and DNA-binding/cleavage studies
Creators: name: Yadav, Manoj Kumar
name: Akhilendra Kumar Maurya
name: Rajput, Gunjan
name: Manar, Krishna Kumar
name: Vinayak, Manjula
name: Drew, Michael G. B.
name: Nanhai Singh
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: New planar trans-copper(II) β-dithioester complexes, [Cu(L)2] (L = methyl-3-hydroxy-(3-pyridyl)-2-propenedithioate (L1 in 1), methyl-3-hydroxy-(2-naphthyl)-2-propenedithioate (L2 in 2), methyl-3-hydroxy-3-(p-methoxyphenyl)-2-propenedithioate (L3 in 3), methyl-3-hydroxy-3-(p-fluorophenyl)-2-propenedithioate (L4 in 4) and methyl-3-hydroxy-3-(p-bromophenyl)-2-propenedithioate (L5 in 5)), have been synthesized and characterized by elemental (C, H, N and S) analysis, ESI-MS, IR and UV-vis spectra. The structures of HL3 and its corresponding complex 3 have been determined by X-ray crystallography. Electrochemical behavior of all complexes has been studied by cyclic voltammetry. All five planar complexes show efficient DNA-binding and DNA(PBR322)-cleavage in a concentration-dependent manner (1>3>5>2>4). Cleavage efficiency is enhanced in the presence of H2O2 as well as ascorbic acid. However, the order of increased efficiency of Cu(II) chelates differs in the presence of H2O2 as 4>1>2>3>5. Among these complexes, the pyridyl- and methoxy-functionalized 1 and 3 have shown higher self-activating capability in DNA-cleavage. All complexes show significant variation in IC50 on MCF-7 cell line. Additionally, treatment with the complexes gradually increases apoptotic cell death in dose-dependent manner in RAW 264.7 cell line. These findings highlight potential cancer protective nature of these complexes.
LEKSIKOLOGIYANI O'QITISH METODIKASI
Creators: name: Narbayeva, Xosiyat
name: Atiyazov, Saparbay
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada, leksikologiyani o‘qitishning turli jihatlari, uning ahamiyati, metodologiyasi, o‘quv dasturlarini ishlab chiqish, samarali o‘qitish usullari, baholash strategiyalari, muammolar va istiqboldagi yo‘nalishlar haqida fikr yuritilgan.
APLIKASI PEMBELAJARAN DI JENJANG PENDIDIKAN DASAR BERBASIS RAMAH OTAK MELALUI BRAIN DEVELOPMENT STRATEGY
Creators: name: Winarso, Widodo
Publisher: name: figshare
Year: 2016
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: Terkait dengan implemtasi kurikulum yang menyangkut pendidikan anak di tingkatan Sekolah Dasar. Pola pendidikan anak di tingkat ini dikenal dengan istilah Pembelajaran tematik terpadu. Hal ini berbeda dengan pembelajaran ditingkatan kelas di atasnya, yang secara khusus mempelajari ilmu dari berbagai disiplin yang berbeda. Pada pembelajaran di tingkat ini semua disiplin ilmu diajarkan tidak secara mandiri, namun secara terpadu yang dikemas dalam tematema tertentu. Bagian inilah yang menarik untuk dikaji. Pada pembelajaran model ini, peserta didik sudah tidak perlu lagi memikirkan sedang belajar mata pelajaran apa, namun peserta didik belajar tentang apa secara holistik. Pembelajaran terpadu menggunakan tema sebagai pemersatu kegiatan pembelajaran yang memadukan beberapa mata pelajaran sekaligus dalam satu kali tatap muka, untuk memberikan pengalaman yang bermakna bagi peserta didik. Karena peserta didik dalam memahami berbagai konsep yang dipelajari selalu melalui pengalaman langsung dan menghubungkannya dengan konsep lain yang telah dikuasainya. Pembelajaran tematik diyakini sebagai salah satu model pembelajaran yang efektif (highly effective teaching model), karena mampu mewadahi dan menyentuh secara terpadu dimensi emosi, fisik, dan akademik di kelas atau di lingkungan sekolah. Model pembelajaran tematik ini terbukti secara empirik berhasil memacu percepatan dan meningkatkan kapasitas memori peserta didik (enhance learning and increase long-term memory capabilities of learners) untuk waktu yang panjang. Model pembelajaran tematik memiliki perbedaan kualitatif (qualitatively different) dengan model pembelajaran lain. Model pembelajaran ini mengoptimasi lingkungan sebagai kunci dalam menciptakan kelas yang ramah. Kondisi belajar dimana aktifitas belajar yang terjadi melibatkan subjek belajar secara langsung, mengoptimasi semua sumber belajar, dan memberi peluang untuk mengeksplorasi secara luas kemampuan kognitif sisiwa melalui aplikasi pembelajaran ramah otak
Pengaruh Motivasi dan Persepsi Siswa pada Matematika Terhadap Prestasi Belajar Matematika Siswa Kelas VIII di MTs Al-Hidayah Dukupuntang Kabupaten Cirebon (Pokok Bahasan Kubus dan Balok)
Creators: name: Winarso, Widodo
name: Nurhana Syamarro
name: Saluky
Publisher: name: figshare
Year: 2016
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: Penelitian ini merupakan hasil pengukuran motivasi, persepsi dan prestasi belajar matematika siswa yang menggunakan pendekatan kuantitatif dengan teknik regresi ganda. Sampel dalam penelitian ini adalah seluruh siswa kelas VIII sejumlah 46 siswa di MTs Al-Hidayah Dukupuntang Cirebon. Data tingkat motivasi dan persepsi siswa diperoleh melalui angket, sedangkan data prestasi belajar matematika diperoleh dari hasil tes matematika pokok bahasan kubus dan balok.
PENGUASAAN KONSEP LINGKARAN TERHADAP KEMAMPUAN SPASIAL MATEMATIKA SISWA POKOK BAHASAN BANGUN RUANG SISI LENGKUNG KELAS VIII SMP NEGERI 1 KOTA CIREBON
Creators: name: Winarso, Widodo
name: Rikanah, Dewi
Publisher: name: figshare
Year: 2016
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: The concept of circle is a basic concept that must be understood for students to learn about curved side three dimentional figure. The connection of concept of circle to learn curved side three dimentional figure can improve students’ spatial ability.
BIBB Fachbeiträge zur beruflichen Bildung: Workflows einer OA-Fachpublikationsreihe
Creators: name: Nelskamp, Britta
Publisher: name: Zenodo
Year: 2024
Subjects: Open Access
Ressortforschung

description: Die Präsentation war Teil eines Online-Workshops am 21.03.2024, der sich an Verantwortliche in Ressortforschungseinrichtungen richtete.

Ziel des Workshops war es, Good-Practice-Beispiele zur Herausgabe von Schriftenreihen in Open Access und diesbezügliche Workflows aufzuzeigen. Die Teilnehmenden waren eingeladen, sich über eigene Rahmenbedingungen, Herausforderungen und Handlungsspielräume auszutauschen.
The Influences Of Metacognition On Mathematic Learning Outcome At SMPN 2 Leuwimunding - Majalengka
Creators: name: Winarso, Widodo
name: LINDA RISMAYANTI NURMALASARI
name: ETI NURHAYATI
Publisher: name: figshare
Year: 2016
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: Mathematics is the basic of science development and has the advantages in daily life. Mathematics also is said as the queen of knowledge, because it has the important role he results of the study of mathematic influenced by internal and external factors. One of the internal factors is the ability of metacognition. For that conducted this study aimed to determine the effect the ability of metacognition on mathematic learning outcomes at SMPN 2 leuwimunding. The method of this research is ex-post facto research with a quantitative approach. The number of samples in this study were 76 students who were taken by random sampling through traditional means. Metacognition variables were measured using questionnaires MAI (metacognitive Awareness Inventory) which was adopted from Scraw & Dennison while studying mathematics outcome variables were measured using the test in the form of an essay. The technique of analysis data for the hypothesis is simple regression technique. The result of this thesis show that the result of hypothesis is tcount = 5,489 bigger than ttable =1,993 than Ho denied and Ha accepted, it means that is influences between metacognitive on learning math and also has the similarity of regression for that variable, that are Y=17,397 + 0, 795X, from that similarity, coefficient of regression is 0,795. It means that every improvement of metacognitive will influence
Open-Access-Publikationen des IAB: Das Online-Magazin IAB-FORUM
Creators: name: Kargus, Andrea
name: Dorsch, Martina
Publisher: name: Zenodo
Year: 2024

description: Die Präsentation war Teil eines Online-Workshops am 21.03.2024, der sich an Verantwortliche in Ressortforschungseinrichtungen richtete.

Ziel des Workshops war es, Good-Practice-Beispiele zur Herausgabe von Schriftenreihen in Open Access und diesbezügliche Workflows aufzuzeigen. Die Teilnehmenden waren eingeladen, sich über eigene Rahmenbedingungen, Herausforderungen und Handlungsspielräume auszutauschen.
Aspek Psikologi, Sosial-Kultural dan Sikap Islam terhadap Perilaku Transeksual di Indonesia
Creators: name: Winarso, Widodo
Publisher: name: figshare
Year: 2016
Subjects: subject: 170105 Gender Psychology
subject: FOS: Psychology

description: The aspect of social issues becomes one of the concerns of contemporary Islam. This aspect is usually discussed and became the hottest news in social life. One might feel having the lack of unanimity in the provision of public attitudes towards him/herself. This is what happened to transsexual and genital surgery people. Those who have and do the things that feel cornered because people assume the actions carried out under the assumption that they have been violated. Transsexual is a person whose way of behaving not same to the appearance of gender roles in general. Transsexual is a person who in the various levels of "breaking" cultural norms about how men and women should have it. A woman, for example, is culturally soft and tender. If a man has such kind of girl character, it's called transsexuals. Some transsexual people are wearing the opposite sex clothes. Transsexual people might change his or her gender, as male changes into a woman, and vice versa. Many things can affect the formation of transsexual behavior; from biological aspect, social-psychological, and cultural aspects. Muslims take a stand against the potential problems that may result from the presence of the transsexual behavior. In spite of these problems, Muslims should be wise in maintaining harmony in the social life of this world.
On the Catalytic Mechanism of Choline Oxidase
Creators: name: Fan, Fan
Publisher: name: Georgia State University
Year: 2006

description: Choline oxidase catalyzes the four-electron oxidation of choline to glycine betaine, a limited number of compounds that accumulate to high levels in cytoplasm to prevent dehydration and plasmolysis in adverse hyperosmotic environments. With this respect, the study of choline oxidase has potential for the development of therapeutic agents that inhibit the biosynthesis of glycine betaine, thereby rendering pathogenic bacteria susceptible to either conventional treatments or the immune system. In this study, the highly GC rich codA gene encoding for choline oxidase was cloned, expressed. The resulting enzyme was purified to high levels, allowing for detailed biochemical, mechanistic and structural characterizations. A chemical mechanism for the reaction catalyzed by choline oxidase was established by using kinetic isotope effects and viscosity effects as probes, in which the choline hydroxyl proton is not in flight in the transition state for CH bond cleavage. Furthermore, these experiments indicated that chemical steps of flavin reduction by choline and betaine aldehyde are rate limiting for the overall turnover of the enzyme. Further mechanistic characterization clearly suggested a hydride transfer mechanism that is fully quantum mechanical. The structure of choline oxidase was resolved at 1.86  resolution in collaboration with the group of Dr. Allen O. Orville, at the Georgia Institute of Technology, providing a structural framework that is consistent with the mechanistic studies. The results of these studies will be presented and discussed in the context of the Glucose-Methanol-Choline oxidoreductase enzyme superfamily, of which choline oxidase is a member.

Previous structural and mechanistic studies of alcohol- and aldehyde-oxidizing enzymes with different cofactors, as well as the biotechnological and biomedical relevance of choline oxidase are presented in Chapter 1. Chapter 3-8 illustrate my studies on choline oxidase, including cloning, expression, purification and preliminary characterizations (Chapter 3), spectroscopic and steady state kinetics (Chapter 4), the determination of the chemical mechanism for alcohol oxidation and the investigation of the involvement of quantum mechanical tunneling (Chapter 5 and 6), the study of aldehyde oxidation (Chapter 7), and the structural determination of choline oxidase by x-ray crystallography (Chapter 8). Chapter 9 presents a general discussion of the data presented.
Central Nervous System Regulation of Fat Cell Lipid Mobilization: The Role of the Sympathetic Nervous System
Creators: name: Foster, Michelle
Publisher: name: Georgia State University
Year: 2006

description: Obesity is a growing disorder in the United States, affecting over 60% of the population. We previously defined sympathetic nervous system (SNS) outflow from brain to white adipose tissue (WAT) using a viral transneuronal tract tracer. SNS innervation of WAT is the principle initiator of lipolysis, whereas decreases in sympathetic drive promote lipid accumulation. Which of the many origins of SNS outflow from brain to WAT results in SNS-mediated changes in lipid mobilization (increases in drive) or accumulation (decrease in drive) is unknown. Previous research indicates that sympathetic denervation blocks lipid mobilization; thus, rostral sites in the neuroaxis connected to WAT via the SNS may promote WAT lipid mobilization. The hypothalamic paraventricular nucleus (PVN) may play a role via its descending projections to the intermediolateral horn of the spinal cord. Therefore, the consequences of PVN lesions (PVNx) on WAT mobilization or accumulation were tested. PVNx resulted in increased lipid accumulation, indicated by increases in retroperitoneal (RWAT) , epididymal (EWAT) , and inguinal WAT (IWAT) pad masses, in fed
hamsters, but PVNx did not block fasting (56 h)-induced lipid mobilization. Because adrenal medullary catecholamines, especially epinephrine, also play a minor role in lipid
mobilization, we tested the contribution of catecholamine release on lipid mobilization
through adrenal demedullation (ADMEDx), with and without PVNx, and found fastinginduced lipid mobilization was not blocked. There was, however, a suggestion that distal denervation of IWAT, with and without ADMEDx, partially blocked lipid mobilization. In addition, evidence suggests SNS also may be an important controller of fat cell proliferation. Surgical denervation of WAT triggers increases in fat cell number (FCN), but have not determined if this FCN increase is due to preadipocyte proliferation or differentiation of preadipocytes into mature fat cells. We also have not demonstrated
what role sensory innervation may have in regulating white adipocyte proliferation.
Therefore, the role of WAT sympathetic or sensory innervation on adipocyte proliferation
was tested. The SNS but not sensory denervation triggered bona fide proliferation as indicated by bromodeoxyuridine plus AD3, a specific adipocyte membrane protein, colabeling. These and previous data suggest that the SNS plays a role in regulating
adiposity.
Problem Solving, Creativity dan Decision Making Dalam Pembelajaran Matematika
Creators: name: Winarso, Widodo
Publisher: name: figshare
Year: 2016
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: Education era of globality provides a challenge for educators to improve the quality of learning. Efforts need to do one of them is changing the way of teaching. This style of teaching which ignores the creativity of learners can be pointed out as the quality stagnancy achievement of learning objectives. Therefore, a good learning where educators can be creative in implementing learning strategies; reasons and the need for a change in strategy from the traditional way of learning mathematics towards more innovative and in accordance with the demands of the times that the learning strategy to support the achievement of five objectives math; and learning that focus on problem-solving, construction creativity learn and can facilitate the learners to construction mathematical knowledge. Learning activities can be run well and in accordance with the curriculum 2013, when the educator presents the teaching materials by applying learning strategies centered on the learner. If only important for educators to change their learning strategies. Eg learning by solving (Problem Solving), build creativity in learning and decision-making capabilities (Decision Making). Thus it can be interpreted that the learning strategy can be used as a reference in designing activity systematic activities in communicating the lesson content for learners to achieve the learning objectives of mathematics
Teacher-pupil ethnicity match and achievement
Creators: name: Driessen, Geert
Publisher: name: MDPI
Year: 2020
Subjects: ethnic match
teacher-student match
ethnicity
achievement

description: In many countries, ethnic minority teachers are strongly underrepresented. It is often assumed that if there were moreminority teachers, minority pupils would achieve much better. This assumption has rarely been empirically tested. Insearch of proof, the present study reviews the literature. 24 relevant studies were found, all pertaining to the US. Thefindings show that there is little empirical evidence that a stronger degree of ethnic match, be it in the form of a one-toonecoupling of teachers to pupils with the same ethnic background, or a larger share of minority teachers at anethnically mixed school, leads to predominantly positive results. Insofar positive effects were found, they apply to agreater extent to subjective teacher evaluations than to objective achievement outcome measures.
Biochemical and Bioinformatics Analysis of CVAB C-Terminal Domain
Creators: name: Guo, Xiangxue
Publisher: name: Georgia State University
Year: 2006

description: Cytoplasmic membrane proteins CvaB and CvaA and the outer membrane protein TolC form the bacteriocin colicin V (ColV) secretion system in Escherichia coli. CvaB functions as an ATP-binding cassette transporter with nucleotide-binding motifs in the C-terminal domain (CTD).  To study the role of CvaB-CTD in the ColV secretion, a truncated construct of this domain was made and over-expressed. Different forms of CvaB-CTD were obtained during purification, and were identified as monomer, dimer, and oligomer on gel filtration. Nucleotide binding was shown critical for the CvaB-CTD dimerization: oligomers could be converted into dimers by nucleotide bindings; the removal of nucleotide from dimers resulted in transient monomers followed by CTD oligomerization and aggregation; no dimer form could be cross-linked from the nucleotide-binding deficient mutant D654H. The spatial proximity of the Walker A site and ABC signature motif in CTD dimer was identified through disulfide cross-linking of mixed CvaB-CTD with mutants A530C and L630C, while mutations did not dimerize individually. Those results indicated that the CvaB-CTD formed a nucleotide-dependent head-to-tail dimer.  
Molecular basis of differential nucleotide bindings was also studied through bioinformatics prediction and biochemical verification. Through sequence alignment and homology modeling with bound ATP or GTP, it was found that the Ser503 and Gln504 on aromatic stacking region (Y501DSQ-loop) of CvaB-CTD provided two additional hydrogen-bonds to GTP, but not to ATP. Site-directed mutations of the  S503A and/or Q504L were designed based on the model. While site-directed mutagenesis studies of Walker A&B sites or the ABC signature motif affected little on the GTP-binding preference, the double mutation (S503A/Q504L) on the Y501DSQ-loop increased both ATP-binding and ATPase activity at low temperatures.  The double mutant showed slight decrease of GTP-binding and about 10-fold increase of the ATP/GTP-binding ratio. Similar temperature sensitivity in nucleotide-binding and activity assays were identified in the double mutant at the same time. Mutations on the Y501DSQ-loop did not affect the ColV secretion level in vivo. Together, the Y501DSQ-loop is structurally involved in the differential binding of GTP over ATP.
Schriftenreihe "BfN-Schriften" - Erstpublikation im Repositorium "BfN-e-dition"
Creators: name: Kepski, Vera
name: Kölbach, Doris
Publisher: name: Zenodo
Year: 2024

description: Die Präsentation war Teil eines Online-Workshops am 21.03.2024, der sich an Verantwortliche in Ressortforschungseinrichtungen richtete.

Ziel des Workshops war es, Good-Practice-Beispiele zur Herausgabe von Schriftenreihen in Open Access und diesbezügliche Workflows aufzuzeigen. Die Teilnehmenden waren eingeladen, sich über eigene Rahmenbedingungen, Herausforderungen und Handlungsspielräume auszutauschen.
A Novel Function of DEAD Box p68 RNA Helicase In Tumor Cell Proliferation And Epithelial-Mesenchymal Transition
Creators: name: Yang, Liuqing
Publisher: name: Georgia State University
Year: 2006

description: Activities of the DEAD box (Asp-Glu-Ala-Asp) family of proteins- including RNA-dependent ATPase and RNA helicase- function in all organisms to sculpt RNA-RNA duplex and RNA-protein complexes, ensuring that necessary rearrangements are rapidly and properly resolved during genetic information processing. Identified as a prototypic member of the DEAD box family and documented as an ATPase and RNA helicase, p68 plays essential and diverse functions in the control of gene expression ranging from pre-mRNA/rRNA processing and mRNA decay/stability to transcriptional activation and initiation. Despite the early implied roles in organ maturation and tumor progression, the functional contributions of p68 to growth/differentiation regulation and cancer development remain undefined. Here, we show c-Abl-dependent phosphorylation of p68 markedly associates with abnormal cell growth and cancer development. Importantly, we characterize an unanticipated signaling module through which p68 functionally contributes to Epithelial-Mesenchymal Transition (EMT) and cell proliferation. p68, which appears to be phosphorylated by c-Abl at tyrosine 593, consequently promotes an EMT through its ability to recruit ?-catenin into cell nucleus via a canonic Wnt/?-catenin axis independent way; accordingly, phosphor-p68 (phosphorylated at tyrosine 593 residue) also stimulates tumor cell growth, which requires the ATPase activity of the protein. These findings define a potential mechanism whereby phosphor-p68 recruits ?-catenin into cell nucleus in ATP hydrolysis driven fashion and cooperatively regulates transcriptional programs that control an EMT. The dissertation thus demonstrates a tight coordination between DEAD box RNA helicase and cancer development.
Personality Type Of Attitude Difference Learning Math Class X SMA Islam Al-Azhar 5 Cirebon
Creators: name: Winarso, Widodo
Publisher: name: figshare
Year: 2016
Subjects: subject: 170103 Educational Psychology
subject: FOS: Psychology

description: Personality is the essential nature of the individual which is reflected in the attitudes oflearners. The uniqueness depending on the type of personality that.Tipe personality affects the attitude in adjusting and socialize with the environment, including in the learningprocess. Learning attitude is a tendency when studying the behavior of an academic nature and is one of the factors that affect learning outcomes. Attitude is sometimes based on emotion and impulse from the inside, with a nice boost it will generate a good learning attitude as well and vice versa. This study aims to determine the differences in students' mathematics learning attitudes based on the type of personality in SMA Islam Al-Azhar 5 Cirebon. The approach used in the quantitative study with descriptive method. The population in this study were high school students the Islamic Al-Azhar 5 Cirebon, while the sample is class X students numbered 98 people. The sampling technique used in this study is the probability sampling by using simple random sampling. Based on the analysis that has been done that there is no difference in the attitude of learning mathematics is based on the type of personality that is significant, it can be seen from F¬hitung one way ANOVA test results conducted Ftable is smaller than 0616 which was 2.7 Ftabel¬ H0 acceptable means there are no significant differences based on the type of personality student learning.
Teacher knowledge and classroom practice: The impact of teacher training and implementation to support a classroom-based early years’ intervention to support language and literacy
Creators: name: Klop, Daleen
name: Barker, Daphne
name: Cain, Kate
name: Carroll, Shelley
name: Visser, Monique
name: Oakhill, Jane
Publisher: name: OSF Registries
Year: 2023

description: Overview of research questions and analytic plans to assess the impact of teaching training and implementation of the Little Stars language and literacy intervention.
MyGene2 automated match report: KLHL3
Creators: name: Team, The MyGene2
Publisher: name: figshare
Year: 2016
Subjects: subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If multiple MyGene2 profiles potentially match on a shared gene of interest, MyGene2 automatically generates a match report summarizing the information in these profiles. This automated match report is shared publicly to help facilitate further research and/or connections between the submitters of the MyGene2 profiles and other interested parties. This is an automated match report for KLHL3.
Identification and Characterization of MvaT and MvaU Global Regulators in Arginine Catabolism and Quorum Sensing of Pseudomonas aeruginosa
Creators: name: Wally, Hassan
Publisher: name: Georgia State University
Year: 2007

description: Arginine utilization in P. aeruginosa as the source of carbon, nitrogen, and energy is controlled by a complicated regulatory mechanism. While ArgR in the presence of exogenous arginine is required for auto-induction of the aotJQMOP-argR operon for arginine uptake and regulation, this operon is subjected to carbon catabolite repression via an unknown mechanism. This study demonstrated that succinate exerted a stronger repression effect than glucose or pyruvate on arginine induction of an aotJ::lacZ fusion in wild type PAO1. Expression of the aotJ::lacZ fusion was analyzed against three different backgrounds, cbrAB, crc, and vfr, that have been suggested to play a role in carbon catabolite repression. These mutations exerted a negative effect on the arginine-responsive induction to different extents, with the order of cbrAB > vfr > crc. A series of aotJ::lacZ fusions with deletions in the aotJ regulatory region were constructed and the effect of exogenous arginine examined in the argR mutant and its parent strain. The results indicated that a 250-bp sequence upstream of the ArgR operator is required for the optimal induction of the operon by exogenous arginine, and revealed the presence of a cryptic promoter (P0) in this region. Electromobility shift assays with crude cell-free extracts of PAO1 revealed that a DNA-binding protein other than ArgR binds to the aforementioned 250-bp region. Through reverse genetics, two regulatory proteins MvaT and MvaU were identified and specifically interacted with the aotJ-argR regulatory region. The MvaT/MvaU are involved in the regulation of the P0 promoter. The importance of  
MvaT and MvaU for bacterial growth was supported by the notion that no true mvaT mvaU double knockout mutant can be constructed. This is the first case to characterize the growth phenotypes of quasi-mvaT mvaU double mutants complemented with fusions for arginine-inducible expression of mvaT or mvaU. Further analysis of the physiological significance of MvaT and MvaU revealed their involvement in swarming response and pyocyanin synthesis. The defect in pyocyanin synthesis was correlated to the diminished level of PQS, an important chemical signal compound in the quorum sensing network of P. aeruginosa.
MyGene2 automated match report: CFH
Creators: name: Team, The MyGene2
Publisher: name: figshare
Year: 2016
Subjects: subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If multiple MyGene2 profiles potentially match on a shared gene of interest, MyGene2 automatically generates a match report summarizing the information in these profiles. This automated match report is shared publicly to help facilitate further research and/or connections between the submitters of the MyGene2 profiles and other interested parties. This is an automated match report for CFH.
MPEC 2025-J06 : 2025 HD19
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 HD19

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
MyGene2 automated match report: NPHP4
Creators: name: Team, The MyGene2
Publisher: name: figshare
Year: 2016
Subjects: subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If multiple MyGene2 profiles potentially match on a shared gene of interest, MyGene2 automatically generates a match report summarizing the information in these profiles. This automated match report is shared publicly to help facilitate further research and/or connections between the submitters of the MyGene2 profiles and other interested parties. This is an automated match report for NPHP4.
MyGene2 automated match report: PKHD1
Creators: name: Team, The MyGene2
Publisher: name: figshare
Year: 2016
Subjects: subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If multiple MyGene2 profiles potentially match on a shared gene of interest, MyGene2 automatically generates a match report summarizing the information in these profiles. This automated match report is shared publicly to help facilitate further research and/or connections between the submitters of the MyGene2 profiles and other interested parties. This is an automated match report for PKHD1.
MyGene2 automated match report: SLC34A1
Creators: name: Team, The MyGene2
Publisher: name: figshare
Year: 2016
Subjects: subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If multiple MyGene2 profiles potentially match on a shared gene of interest, MyGene2 automatically generates a match report summarizing the information in these profiles. This automated match report is shared publicly to help facilitate further research and/or connections between the submitters of the MyGene2 profiles and other interested parties. This is an automated match report for SLC34A1.
Open letter to The Independent - Pilots 'very likely' to misjudge flying conditions due to irrational decisions, revisited
Creators: name: J Perezgonzalez
Publisher: name: figshare
Year: 2017
Subjects: subject: Applied Psychology
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 170202 Decision Making
subject: 170110 Psychological Methodology, Design and Analysis
subject: 179999 Psychology and Cognitive Sciences not elsewhere classified

description: Staufenberg’s news article (2016) comments on research reported by Walmsley and Gilbey (2016). An interview with the corresponding author also yielded extra information, especially the verbalization that practically all pilots fell prey to cognitive biases and the hint that pilots were making irrational decisions.In reality, Walmsley and Gilbey’s own results do not support much of the conclusions posed. I have further expanded on information which is specific to Staufenberg’s news article, especially information about minima meteorological conditions for visual flight rules (VFR) flying in the UK, as well as a breakdown of the percentage of pilots in Walmsley and Gilbey’s study which contradicts the information provided.
Structure and Function of Escherichia Coli Seca: An Essential Component of the Sec Translocase
Creators: name: Na, Bing
Publisher: name: Georgia State University
Year: 2007

description: E. coli SecA is an essential component for protein translocaiton across membrane. SecA can be deleted from its N- and/or C-terminal ends without losing complementation activity. In this study, we determined the dispensity of both ends of SecA molecule. The minimal length at the SecA C-terminus is dependent on the length of the N-terminal region. SecA10-826 and SecA22-829 are the two minimal length SecAs. One more amino acid deleted at the C-terminal end completely abolished their complementation activity. A hydrophobic amino acid is required at the 826th amino acid in the minimal-length SecAs. Both SecA22-828 and SecA22-829 could form a dimer, and have decreased ATPase and protein translocation activities. The active truncated SecA mutants tended to have more soluble form than membrane-bound form, but were stably embedded in membrane. In contrast, the inactive truncated SecA mutants tended to have more membrane-bound form, but were not stable in membrane. Thus, the loss of complementation is not related to dimerization, ATPase and translocation activity but to certain extent related to their biased subcelluar localization and conformation in membrane.
Isolated membranes of E coli strains were solubilized and fractionated by sucrose gradient fractionation. These membranes fractions were depleted of SecY and YidC, but contained SecD, SecF and GroEL. Proteoliposomes reconstituted from these fractionated membrane proteins were active in pOmpA translocation which required SecA and ATP. Membrane fractions from strain CK1801 in which the unc gene is deleted were reconstituted into liposomes and also showed translocation activities. Moreover, proteoliposomes reconstituted with Bacteriorodopsin alone were not active in translocation, while proteoliposomes reconstituted with Bacteriorodopsin and CK1801 membrane fractions showed elevated translocation efficiency. These data suggested that proton motive force is not obligatory for, but stimulatory to translocation of pOmA. Purified GroEL was reconstituted into lipsomes and the reconstituted proteoliposomes were active in pOmpA translocation although at lower efficiency. This translocation also required SecA and ATP. These results together suggested that translocation of pOmpA is active in the absence of SecY and YidC. In the absence of SecYEG, translocation of pOmpA requires SecA and ATP. GroEL, SecD and SecF may participate in the SecY-independent translocation.
Enabling Interactive Notebooks on Supercomputers with Jupyterhub
Creators: name: Shreyas Cholia
name: R. Shane Canon
name: Thomas, Rollin
Publisher: name: figshare
Year: 2017
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: 80501 Distributed and Grid Systems
subject: Applied Computer Science
subject: Computer Software
subject: 80505 Web Technologies (excl. Web Search)

description: Interactive notebook systems such as Jupyter represent a new paradigm in web science gateways that can combine interactive code execution with data analysis and exploration. In our work we demonstrate how one can create and manage interactive notebooks in a multi-user supercomputing environment using the Jupyterhub platform. We describe our architecture along with custom modules that we developed for Jupyterhub to manage authentication, notebook execution and interaction with the job queueing system. We illustrate the power of this system through the OpenMSI use case, and outline future directions for this effort.
Containers-as-a-service via the Actor Model
Creators: name: Stubbs, Joe
name: Rion Dooley
name: Vaughn, Matthew
Publisher: name: figshare
Year: 2017
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: 80501 Distributed and Grid Systems
subject: Applied Computer Science
subject: Computer Software
subject: 80505 Web Technologies (excl. Web Search)

description: Modern science gateways face distributed systems engineering challenges from multiple fronts. In this extended abstract, we introduce Abaco (Actor Based Containers), a framework and hosted service based on Linux containers and the actor model of concurrent computing for tackling problems related to portability, scalability, reproducibility, and the heterogeneity of physical infrastructure powering science gateways. We describe the initial implementation of Abaco, its use in the Agave science-as-a-service platform, as well as some related projects and areas of future work.
Demo: Pegasus Scientific Workflows within HUBzero
Creators: name: Rynge, Mats
name: Vahi, Karan
name: Clark, Steven
Publisher: name: figshare
Year: 2017
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: 80501 Distributed and Grid Systems
subject: Applied Computer Science
subject: Computer Software
subject: 80505 Web Technologies (excl. Web Search)

description: The HUBzero platform for scientific collaboration enables tool developers to build tools that are easily shared with both researchers and educators. This enables users to login and start their analysis without worrying about setup and configuration of the tools. Once the analysis is done, researchers can analyze the results using various inbuilt capabilities for plotting and visualization. To facilitate handling of more complex workloads, we have integrated Pegasus Workflow Management System with “submit”, the main tool used by tool developers in HUBzero to submit analysis to local and remote compute resources. Pegasus WMS provides a means for representing the application workflow in an abstract form which is independent of the resources available to run it and the location of data and executables. It compiles these abstract workflows into an executable form that can be executed on local or remote distributed resources. Pegasus also captures all the provenance of the workflow lifecycle from the planning stage, through execution, to the final output data. This enables users to easily debug and monitor their computations that occur on remote resources. The advanced data management capabilities of Pegasus allow the tool developers to execute the tightly coupled parts of their workloads on a HPC cluster, while farming out remaining tasks to a distributed HTCondor based computing infrastructure. The demo will give an introduction to scientific workflows with Pegasus and focus on integration of Pegasus WMS with “submit”, and how it enables tool developers using the Rappture toolkit or “submit” directly to use scientific workflows.
Containers-as-a-service via the Actor Model
Creators: name: Stubbs, Joe
name: Rion Dooley
name: Vaughn, Matthew
Publisher: name: figshare
Year: 2016
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: 80501 Distributed and Grid Systems
subject: Applied Computer Science
subject: Computer Software
subject: 80505 Web Technologies (excl. Web Search)

description: Modern science gateways face distributed systems engineering challenges from multiple fronts. In this extended abstract, we introduce Abaco (Actor Based Containers), a framework and hosted service based on Linux containers and the actor model of concurrent computing for tackling problems related to portability, scalability, reproducibility, and the heterogeneity of physical infrastructure powering science gateways. We describe the initial implementation of Abaco, its use in the Agave science-as-a-service platform, as well as some related projects and areas of future work.
Demo: Pegasus Scientific Workflows within HUBzero
Creators: name: Rynge, Mats
name: Vahi, Karan
name: Clark, Steven
Publisher: name: figshare
Year: 2016
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: 80501 Distributed and Grid Systems
subject: Applied Computer Science
subject: Computer Software
subject: 80505 Web Technologies (excl. Web Search)

description: The HUBzero platform for scientific collaboration enables tool developers to build tools that are easily shared with both researchers and educators. This enables users to login and start their analysis without worrying about setup and configuration of the tools. Once the analysis is done, researchers can analyze the results using various inbuilt capabilities for plotting and visualization. To facilitate handling of more complex workloads, we have integrated Pegasus Workflow Management System with “submit”, the main tool used by tool developers in HUBzero to submit analysis to local and remote compute resources. Pegasus WMS provides a means for representing the application workflow in an abstract form which is independent of the resources available to run it and the location of data and executables. It compiles these abstract workflows into an executable form that can be executed on local or remote distributed resources. Pegasus also captures all the provenance of the workflow lifecycle from the planning stage, through execution, to the final output data. This enables users to easily debug and monitor their computations that occur on remote resources. The advanced data management capabilities of Pegasus allow the tool developers to execute the tightly coupled parts of their workloads on a HPC cluster, while farming out remaining tasks to a distributed HTCondor based computing infrastructure. The demo will give an introduction to scientific workflows with Pegasus and focus on integration of Pegasus WMS with “submit”, and how it enables tool developers using the Rappture toolkit or “submit” directly to use scientific workflows.
Enabling Interactive Notebooks on Supercomputers with Jupyterhub
Creators: name: Shreyas Cholia
name: R. Shane Canon
name: Thomas, Rollin
Publisher: name: figshare
Year: 2016
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: 80501 Distributed and Grid Systems
subject: Applied Computer Science
subject: Computer Software
subject: 80505 Web Technologies (excl. Web Search)

description: Interactive notebook systems such as Jupyter represent a new paradigm in web science gateways that can combine interactive code execution with data analysis and exploration. In our work we demonstrate how one can create and manage interactive notebooks in a multi-user supercomputing environment using the Jupyterhub platform. We describe our architecture along with custom modules that we developed for Jupyterhub to manage authentication, notebook execution and interaction with the job queueing system. We illustrate the power of this system through the OpenMSI use case, and outline future directions for this effort.
Analysis of nanoHUB.org from a Business Perspective
Creators: name: Zentner, Lynn
name: Zentner, Michael
name: Klimeck, Gerhard
Publisher: name: figshare
Year: 2017
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences
subject: 80501 Distributed and Grid Systems
subject: Applied Computer Science
subject: Computer Software
subject: 80505 Web Technologies (excl. Web Search)

description: Science Gateways are typically implemented by scientists and cyberinfrastructure experts to serve a specific, externally-funded scientific focus. Sustainability of those gateways and the knowledge and tools they contain continues to be of strong interest to both the gateways and the funding agencies that support their creation and initial operation. nanoHUB.org is an established gateway entering its 15th year of operation and now serving over 1.4 million visitors annually. The leadership at nanoHUB have utilized a partnership with Purdue’s Krannert School of Management to collaborate on examining nanoHUB from a business perspective. The results of these collaborations are outlined in this extended abstract and will be expanded upon in the corresponding presentation.