cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
INFLUENCE OF COFFEE CONSUMPTION ON DNA INTEGRITY IN HUMANS
Creators: name: RICHLING, Elke
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Epidemiologic evidence suggests coffee consumption to be associated with reduced risk due to certain diseases, including diabetes type 2, Parkinson, and cardiovascular disease or various types of cancer. In human interventions studies we investigated effects of regular coffee consumption on DNA integrity in peripheral white blood cells (WBC) by the comet assay. During four weeks, volunteers daily ingested three large cups (250 ml) of a specific coffee blend, rich in both, green bean constituents and roast products. Controls received the same volume of water. The results allow the conclusion that regular coffee consumption is associated with markedly reduced DNA strand breaks, reflecting total as well as background DNA damage. In a recently performed short term study, when volunteers consumed four cups of coffee (200 ml) every two hours the results showed a significant reduction of background DNA strand breaks in comparison to baseline. Interestingly, this DNA protective effect was detected already two hours after the first coffee consumption.
Taken together, our studies clearly showed that consumption of coffee reduces DNA damage in white blood cells of humans.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
ANTHOCYANINS AND CELLULAR REDOX SIGNALING: NRF2 AND NF-KB AS TARGETS
Creators: name: CIMINO, Francesco
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Reactive oxygen species (ROS) serve important physiological functions in host defense, and constitute an important second messenger in cell signaling transduction, but several chronic pathological conditions are associated with a status of oxidative stress, that is an unbalance between ROS formation and antioxidant availability. Many plant antioxidants, have been shown able to prevent free radical-related diseases by counteracting cell oxidative stress. However it is now considered that the in vivo beneficial effects of these phytochemicals are unlikely to be explained just by their antioxidant capability. Several plant antioxidants like anthocyanins exhibit hormetic properties, by acting as ‘low-dose stressors’ that may prepare cells to resist more severe stress. The discovery of specific genes (HO-1, NQO1, g-GCS) and pathways (redox sensitive Nrf2, NF-kB regulated signaling) affected by antioxidants, led to the hypothesis that anthocyanins may act as modulators of gene regulatory and signal transduction pathways. Since activation of endogenous cellular defense mechanisms can represent an innovative approach to therapeutic intervention in pathological conditions characterized by chronic tissue damage, a better understanding of adaptive response mechanisms induced by plant antioxidants at the cellular and molecular levels can lead to novel strategies for the prevention and treatment of many different diseases. The adaptive responses induced by anthocyanins, as well as the molecular mechanisms involved in such responses, will be discussed.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
The Linear Regression Family in R
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2020
Subjects: R
Analysis
Linear regression

description: Dr. Mowinckel's blog:   Let's talk linear regression.  It's the thing we learn about first year in psychology at Uni, and it blows all our minds that we are doing _math_ in psychology.  An unfortunate effect of all high school student counsellors in Norway thinking all psychologists do is shrink people's heads.  And then here we come to Uni and first semester they stick us with _math_.
Index of Publications. The Bovine Practitioner 1989-1994 / Proceedings of the Annual Meetings 1989-1994
Creators: name: Bovine Practitioners, American Association Of
Publisher: name: The Bovine Practitioner
Year: 1995

description: Author and subject indexes for the Bovine Practitioner and the Proceedings of the Annual Meetings, 1989-1994.
description: The Bovine Practitioner, Bovine Practitioner. Indexes.
Extracting polyphenols: trying to get the best
Creators: name: Valentão, Patricia
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Nature has been a prolific source of interesting compounds for many years. Polyphenols are secondary metabolites found in both terrestrial and marine organisms. They are grouped in several classes resulting from acetate and/or shikimate pathways, being recognized for having a wide array of biological properties. Nevertheless, the exploitation of many plant materials and marine organisms as sources of these compounds is still reduced, due to the lack of popularity or commercial interest. The suitable extraction procedure depends on the class of compounds and on the matrix in which they are contained. Case studies, involving different procedures to obtain bioactive natural extracts enriched in phenolic compounds from distinct classes, will be focused. Terrestrial and marine-derived extracts, containing phlorotannins, flavonoids and cinnamoyl derivatives, and their interference in SNC and gastrointestinal disorders, skin aging and fungal infections will be presented.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
INFLUENCE OF COPIGMENTATION ON THE STABILITY
OF SPRAY DRIED ANTHOCYANINS
Creators: name: WEBER,
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Anthocyanin rich extracts from several fruits and purified anthocyanins are frequently applied as food colorants, due to the growing awareness of consumers concerning synthetic food additives. Nevertheless, these natural pigments often show poor stability and alongside a rapid loss of coloring properties. A suitable approach for encapsulating and stabilizing of anthocyanin extracts is spray drying. The effects of added copigments (rutin and ferulic acid) on the storage stability of spray dried anthocyanins from blackberry were investigated. Modelling of the degradation kinetics revealed that degradation during storage under light and different temperatures all showed first order kinetics whereby light had a greater impact on anthocyanin stability than elevated temperatures. The addition of copigments led to considerably higher anthocyanin stability compared to samples without copigments and to increased half-life values of the obtained powders regarding color properties. This stabilizing effect may be attributed to the antioxidative properties of the copigments and prevention of the hydration of the anthocyanins during the spraying process.
The observed color changes did not correlate with the anthocyanin loss, assuming that degradation of anthocyanin did not only lead to the formation of colorless products but also evoked colored derivatives and polymers.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
title: Proteome-Transcriptome Alignment of Molecular Portraits by Self-Contained Gene Set Analysis: Breast Cancer Subtypes Case Study
Creators: name: Ayaluri, Koushik
Publisher: name: George Mason University
Year: 2021
Subjects: subject: Gene set analysis
subject: Proteome transcriptome
subject: Self-contained analysis
subject: Transcriptome alignment
subject: Breast cancer

description: Gene sets are formed by grouping together functionally related genes or pathways. Gene set analysis (GSA) is a method previously developed for examining transcriptome data. As the gene sets are unit of expression in transcriptome-level GSA, similarly, the unit of protein abundance may be used for proteomics GSA. Self-contained and Competitive are two GSA approaches which differ by their underlining null hypothesis. In Self-contained approach, each gene set is evaluated to check if it is expressed differentially between two phenotypes. In Competitive approach, each gene set is compared to all the genes except the genes in that set. Competitive approaches are rapidly becoming popular for analyzing proteomics data, as much as they were for transcriptomics data. This research applied Self-contained GSA test of Gene sets net correlations analysis (GSNCA) to proteomics data of 77 annotated samples of breast cancers. Regardless of significant variation in the structure of proteomics and transcriptomics data, many pathway-wide characteristics features of breast cancer molecular subtypes were replicated at the protein level. In this work, GSA yielded a set of observations visible at proteome level, such as mitotic cell cycle process involvement in the HER2 molecular subtype. Overall, this study proves the value of Gene Sets Net Correlation Analysis (GSNCA) approach as a critical tool for analyzing proteomics data in general, and for dissecting protein-level molecular portraits of breast cancer tumors, in particular.
EXPLORING THE HIGH THROUGHPUT POTENTIAL OF MICROEXTRACTION TECHNIQUES FOR THE ISOLATION OF LOW-MOLECULAR WEIGHT POLYPHENOLS IN DIFFERENT FOOD MATRICES
Creators: name: PORTO-FIGUEIRA P.,
name: FIGUEIRA J.A.,
name: PEREIRA Jorge,
name: CAMARA, José S
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Polyphenols are widespread constituents of several foods matrices, including fruits, vegetables, cereals, olive and legumes, juices and beverages such as tea, coffee, beer and wine. Despite their wide distribution, the health effects of dietary polyphenols have come to the attention of nutritionists namely in recent years. The preventive effects of these secondary plant metabolites in terms of cardiovascular, neurodegenerative diseases and cancer are deduced from epidemiologic data as well as in vitro and in vivo studies.
The selection of the proper analytical strategy for studying phenolics in food matrices depends on the purpose of the study as well as the nature of the sample and the target analyte. Conventional extraction techniques, as solid-phase extraction andor liquid-liquid extraction, represented for long time the gold standard for sample preparation. However, during the last decade, downstream analytical procedures evolved very significantly, making sample preparation a serious bottleneck in the analytical workflow.
In this sense, extraction and characterization of dietary polyphenols will be explored as a case study to demonstrate how modern microextraction strategies solutions, as MEPS, m-SPEed and m-QuEChERS, are fostering the whole analytical workflow and performance. The potentialities of new sorbents and nanomaterials tailored for microextration of specific compounds will be also addressed.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
title: Snapshots and Springs: Analyzing and Reproducing the Motions of Molecules
Creators: name: Morris, David
Publisher: name: George Mason University
Year: 2018
Subjects: subject: Protein dynamics
subject: Energy landscape
subject: Sampling
subject: Normal mode analysis

description: Nearly all cellular processes involve proteins structurally rearranging to accommodate molecular partners. The energy landscape underscores the inherent nature of proteins as dynamic molecules interconverting between structures with varying energies. Reconstruct- ing a proteins energy landscape holds the key to characterizing the structural dynamics and its regulation of protein function. In practice, the disparate spatio-temporal scales spanned by the slow dynamics challenge wet and dry laboratories. The growing number of deposited structures for proteins central to human biology presents an opportunity to infer the relevant dynamics. Recent computational efforts using extrinsic modes of motion as variables have successfully reconstructed detailed energy landscapes of several medium-size proteins. Here we investigate the extent to which one can reconstruct the energy landscape of a protein in the absence of sufficient, wet-laboratory structural data. We do so by integrating intrinsic modes of motion extracted off a single structure in a stochastic optimization framework that supports the plug-and-play of different variable selection strategies. We demonstrate that, while knowledge of more wet-laboratory structures yields better-reconstructed landscapes, precious information can be obtained even when one structural model is available. The presented work opens up interesting venues of research on structure-based inference of dynamics. Added data with a second protein suggests that the findings are not specific to the molecules analyzed.
Absurdities, Ironies, Hyper-Production and Artificial Bogeymen
Creators: name: Lenardic, Adrian
Publisher: name: Zenodo
Year: 2024
Subjects: Publication Overload
Publication Strain
Science Publishing
For-Profit Publishers
Growth of Science
Artificial Intelligence

description: This piece is an expanded version of a short letter to the editor about an article that appeared in Nature. The Nature article was titled "Is ChatGPT making scientists hyper-productive?" The original letter to the editor pointed out that the article made a temporal freeze frame error and was presented in a mode of disingenuous questioning that would hamper community wide self-examination into the issue of science production. The editors passed - no hard feelings. This piece expanded the letter to address issues related to what has come to be termed 'publication overload' (also called 'publication strain' in some studies).
R-Package Advent Calendar 2020
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2020
Subjects: R
Advent calendar
Packages

description: Dr. Mowinckel's blog: This year has been truly something different for us all.  Blogging has definitely taken a toll, as real life has been quite something to handle. So, in order to end the year with a bang, and something fun, I started a twitter advent calendar!
THE REACTION OF URBAN FOREST STANDS  TO ADDITIONAL SNOWMAKING
Creators: name: A.E. Konovalova
name: М.E. Konovalova
name: I.V. Kosov
Publisher: name: Zenodo
Year: 2025

description: Three stands inspection of urban forests in Krasnoyarsk on the territory of the Biathlon Academy sports facility was conducted. The changes in the wood volume of tree stand, dead-standing and dead fallen stand density and tree basal area in birch, pine and aspen forests for the period 2018-2022 after the completion of work on the equipment of the trails and artificial snowmaking system were analyzed. The study was identified the stand degradation at all three sample plots. The aspen trees condition requires urgent measures for the forest reconstruction. Despite the younger biological age of pine stand, the degradation processes in it require comprehensive actions to improve the sanitary condition of the stand, its partial reconstruction and to reduce the negative effects of artificial snowing. In old-age birch stand, timely forest restoration o is sufficient.
title: Milton Barnes to Rhoda Barnes, November 27, 1863.
Creators: name: Barnes, Milton
Publisher: name: George Mason University
Year: 2011
Subjects: subject: Missionary Ridge (Tenn. and Ga.)
subject: Civil War campaigns

description: Public domain. There are no known use restrictions.
description: Letter to Rhoda Barnes from her husband Milton Barnes, stationed in Chattanooga, Tennessee. Milton recounts the battle at Missionary Ridge fought on November 25. He mentions many of the commanding officers involved including General Braxton Bragg and Major General Ulysses S. Grant. Milton lists those killed or wounded from his regiment.
Simplified Object Detection for Manufacturing : Introducing a Low-Resolution Dataset
Creators: name: Werheid, Jonas Maximilian
name: He, Shengjie
name: Hamann, Tobias
name: Abdelrazeq, Anas
name: Schmitt, Robert H.
Publisher: name: RWTH Aachen University
Year: 2024
Subjects: Computer Vision
Dataset
Manufacturing
Object Detection
Quality Classification

description: 13 Seiten (2024). doi:10.18154/RWTH-2024-07221
title: Examining Elementary Students’ Development of Intercultural Competence Through Self-Regulatory Prompts
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2022
Subjects: subject: Intercultural attitudes
subject: Intercultural competence
subject: Intercultural knowledge
subject: Intercultural skills
subject: Self-regulated learning
subject: Self-regulatory prompts
subject: Education
subject: Educational psychology

description: The purpose of the present quasi-experimental mixed-methods study was to examine the effects of an Intercultural Competence Intervention with Self-Regulatory Prompts (ICI-SRP) on elementary students’ development of intercultural knowledge, skills, and attitudes, and their self-efficacy beliefs in self-regulating their intercultural learning, and to investigate the ways in which self-regulatory prompts (SRP) influence elementary students’ activation of self-regulatory strategies in intercultural learning. Twenty (N=20) Montessori elementary students from two Montessori schools participated in four sessions of an intercultural exercise, in which only the experimental group were given SRP. It was hypothesized that the experimental group’s use of SRP would further enhance the participants’ development of intercultural knowledge, skills, and attitudes and their self-efficacy beliefs in self-regulating their intercultural learning. Quantitative data collected from the ICI-SRP survey was analyzed by conducting a univariate analysis of covariance (ANCOVA) for each of its four subscales and was used to examine the effects of SRP on the students’ development of intercultural competence (IC) and self-efficacy beliefs in self-regulating intercultural learning. Qualitative data collected from focus groups was analyzed using the constant comparative method to shed light on the ways in which SRP influence the students’ activation of self-regulatory strategies in intercultural learning. Results from the ANCOVA did not support the hypothesis, as they showed non-statistically significant differences between the development of intercultural knowledge, skills, and attitudes, and the self-efficacy beliefs in self-regulating intercultural learning in both groups. Results from the ANCOVA showed numerical increases in intercultural knowledge, skills, and attitudes in both groups, and numerical decreases in the self-efficacy beliefs in self-regulating intercultural learning in both groups. Findings from the analysis of the focus group data were mostly aligned with the data from the ANCOVA. Data from the focus groups shed light on different types of IC knowledge, skills, and attitudes, and different types of planning and monitoring applied by participants of both groups. The overall findings of the present study suggest that it is likely for elementary aged students to develop IC through intercultural exercises, and that SRP may support that development under certain conditions. The findings of the study may contribute to the development of elementary students’ intercultural learning methods and tools.
NON-EXTRACTABLE POLYPHENOLS OR MACROMOLECULAR ANTIOXIDANTS IN PLANT FOODS: CONTENT, ISOLATION AND POTENTIAL APPLICATIONS
Creators: name: SAURA-CALIXTO, Fulgencio
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The predominant approach to health effects of dietary antioxidants and the market of antioxidants are currently focussed on substances with small molecular size (Vitamin C, Vitamin E, polyphenols, carotenoids and others). However, the presence of appreciable amount of macromolecular antioxidants (MACAN) in plant food and diets have been recently reported. These are either non-extractable polymeric polyphenols or single polyphenols and carotenoids linked to polysaccharides and protein, which exhibit a significant biological activity and promising health effects. Results on MACAN content in the edible part and in the peels of most consumed fruits in Europe will be reported. Potential applications of MACAN as functional ingredient in food and beverages will be addressed, including some patents recently registered.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
New {ggseg} with Geom!
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2021
Subjects: R
Neuroimaging
ggseg

description: Dr. Mowinckel's blog:   A couple of months ago, we released a new version of our ggseg R-package for visualisations of brain atlases.  I had been wanting to create such an update for a long time, but getting the internal logics of a ggplot geom working as I wanted was rather difficult. Likely because I was trying to do too many things, but, hey... that's me!
THE POTENTIAL OF PLANT PHENOLICS IN PREVENTION
AND THERAPY OF SKIN DISORDERS
Creators: name: KULMA, Anna
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Besides the beneficial effects on the plant host, phenolic compounds exhibit a series of biological properties that influence the human in a health-promoting manner. Evidence suggests that people can benefit from plant phenolics obtained either by the diet or through skin application. Phenolic compounds are a promising tool in eliminating the causes and effects of skin aging, skin damage, including wounds, burns and skin diseases such as bacterial infections or even skin cancer. Phenolic compounds are effective both as a single components and as parts of a plant extracts.
Their mechanism of action involves antioxidative action, influence on enzyme activity and regulation of gene expression. The phenolics can be isolated from a variety of plants, both exotic in origin and those commonly cultivated for food. One of the industrial sources of phenolics which could be potentially used in human therapy is flax, Linum ussiatissimum. Varieties of this plant are grown for fibre and oil and by products such as seed cakes, short fibre and shives are source of valuable components including lignans, phenolic acids and flavonoids.
Based on those products we developed series of preparation which could be effective in treatment of various skin disorders including bacterial infection, inflammation and long standing- non healing wounds. In most cases the effect was shown only in in vitro culture so far, however in case of a wound dressing the effect was confirmed in a pre- clinical pilot study.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
title: The soft X-ray and XUV split-and-delay unit at beamlines FL23/24 at FLASH2
Creators: name: Dreimann, Matthias
name: Wahlert, Frank
name: Eckermann, Dennis
name: Rosenthal, Felix
name: Roling, Sebastian
name: Reiker, Tobias
name: Kuhlmann, Marion
name: Toleikis, Sven
name: Brachmanski, Maciej
name: Treusch, Rolf
name: Plönjes, Elke
name: Siemer, Björn
name: Zacharias, Helmut
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2025
Subjects: subject: 530 Physics

description: A split-and-delay unit for the extreme ultraviolet and soft X-ray spectral regions has been built which enables time-resolved experiments at beamlines FL23 and FL24 at the Free-electron LASer in Hamburg (FLASH). Geometric wavefront splitting at a sharp edge of a beam splitting mirror is applied to split the incoming soft X-ray pulse into two beams. Ni and Pt coatings at grazing incidence angles have been chosen in order to cover the whole spectral range of FLASH2 and beyond, up to hν = 1800 eV. In the variable beam path with a grazing incidence angle of ϑd = 1.8°, the total transmission (T) ranges are of the order of 0.48 < T < 0.84 for hν < 100 eV and T > 0.50 for 100 eV < hν < 650 eV with the Ni coating, and T > 0.06 for hν < 1800 eV for the Pt coating. For a fixed beam path with a grazing incidence angle of ϑf = 1.3°, a transmission of T > 0.61 with the Ni coating and T > 0.23 with a Pt coating is achieved. Soft X-ray pump/soft X-ray probe experiments are possible within a delay range of −5 ps < Δt < +18 ps with a nominal time resolution of tr = 66 as and a measured timing jitter of tj = 121 ± 2 as. First experiments with the split-and-delay unit determined the averaged coherence time of FLASH2 to be τc = 1.75 fs at λ = 8 nm, measured at a purposely reduced coherence of the free-electron laser.
description: Finanziert über die DEAL-Vereinbarung mit Wiley, Springer oder Elsevier 2019–2023.
title: Correspondence: Watkins M. Abbitt and C. Harrison Mann, Jr.; June 13, 1968-June 21, 1968
Creators: name: Abbitt, Watkins M.
name: Mann, Charles Harrison, Jr., 1908-1977
Publisher: name: George Mason University
Year: 2006
Subjects: subject: United States Constitution

description: Letter A: typescript signed, 8" x 10.5" (20.3cm x 26.7cm); Letter B: typescript unsigned, 8.5" x 11" (21.6cm x 27.9cm)
description: Correspondence between Watkins M. Abbitt, Representative from Virginia, regarding revising Sec. I, Article III of the United States Constitution to make federal judges subject to review. C. Harrison Mann, Jr. Collection 3.20
Using GitHub Actions to Build your Hugo Website
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2021
Subjects: hugo
Continuous Integration
GitHub Actions

description: Dr. Mowinckel's blog:   Lately, I've been doing some work in getting [Hugo]() websites building through Github actions, and then have them deployed with Netlify.  Of course, once we are building with GitHub actions we _could_ also just use GitHub pages to deploy, and I'll show how you can do that too, even if I will keep using Netlify.
title: American National Theatre Album
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 1995
Subjects: subject: ANTA Album
subject: Music Box Revue
subject: Three's A Crowd
subject: Lady Be Good
subject: Abe Lincoln in Illinois
subject: Two For The Show
subject: Smilin' Through
subject: Knickerbocker Holiday
subject: The Shanghai Gesture
subject: Saint Joan
subject: Oklahoma
subject: Fifty Million Frenchmen
subject: Wake Up And Dream
subject: Ziegfeld Follies
subject: Show Boat
subject: Victoria Regina
subject: Winged Victory
subject: The Passing Show Of 1921
subject: Come Of Age
subject: Mums' The Word
subject: The Front Page
subject: Porgy and Bess
subject: Hamlet
subject: Pal Joey
subject: The Show Is On
subject: ANTA
subject: Ziegfeld Theatre
subject: Serlin, Oscar
subject: Crawford, Cheryl
subject: Hammerstein, Oscar
subject: Rodgers, Richard
subject: Freedley, Vinton
subject: Sherman, Hiram
subject: Meth, Max
subject: Berlin, Irving
subject: Schwartz, Arthur
subject: Bolton, Guy
subject: Thompson, Fred
subject: Gershwin, George
subject: Gershwin, Ira
subject: Sherwood, Robert E.
subject: Hamilton, Nancy
subject: Lewis, Morgan
subject: Martin, Allan Langdon
subject: Anderson, Maxwell
subject: Weill, Kurt
subject: Colton, John
subject: Fields, Herbert
subject: Porter, Cole
subject: Houseman, Lawrence
subject: Hart, Moss
subject: Rose, David
subject: Atteridge, Harold
subject: Dane, Clemence
subject: Savo, Jimmy
subject: Hecht, Ben
subject: Mac Arthur
subject: Heyward, DuBose
subject: Shakespeare, William
subject: O'Hara John
subject: Shaw, George B.

description: Program.
RESVERATROL MODULATES CELL MEMBRANES: WHAT’S THE STORY?
Creators: name: NEVES, Ana Rute
name: ALMEIDA, Francisca Mendes
name: NUNES,
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Resveratrol is one of the most promising naturally occurring polyphenols with great therapeutic potential. Despite the well know anti-oxidant activity, anti-inflammatory action, cardiovascular protection, neuroprotection and cancer chemoprevention, the mechanism of action of resveratrol is still uncertain. This work brings a new membrane approach to understand resveratrol action through the modulation of lipid domains present in biological membranes, and consequently the activity of anchored proteins that are involved in intracellular cascades. The potential molecular interactions between resveratrol and lipid rafts found in cell membranes were assessed by means of Förster resonance energy transfer, X-ray diffraction analysis, derivative spectrophotometry, fluorescence quenching and anisotropy studies. This polyphenol compound seems to induce phase separation in lipid bilayers, stabilizing and promoting the formation of ordered domains (lipid rafts) which can act as organizing centers for the assembly of proteins involved in cell signaling pathways.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
title: Creating a Popular Romance Collection in an Academic Library, PCA Presentation
Creators: name: Sheehan, Sarah
Publisher: name: George Mason University
Year: 2015
Subjects: subject: Popular romance novels
subject: Romance novels
subject: Popular culture association
subject: Academic libraries
subject: Libraries

description: Presentation at the Popular Culture Association/American Culture Association 45th Annual Conference in New Orleans, LA April 1st-4th, 2015
description: Over the past few decades, there has been a growing critical mass of scholarly interest in the study of popular romance fiction as a literary form in its own right. While much of the scholarship is available in academic libraries, few of the actual romance novels are. In response to curricular and faculty demand, two librarians decided to start a collection of popular romance novels at their academic library. This article discusses their rationale, methods, and process in creating the collection. Future directions and recommendations for other libraries are also given.
Supplementary document for Design of wavelength division multiplexing devices based on tunable edge states of valley photonic crystals - 6357139.pdf
Creators: name: Wang, xiaorong
name: Han, Yuhui
name: Fei, Hongming
name: Lin, Han
name: Zhang, Mingda
name: liu, xin
name: cao, binzhao
name: Yang, Yibiao
name: Chen, Zhihui
name: Xiao, Liantuan
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Design of wavelength division multiplexing devices based on tunable edge states of valley photonic crystals
title: Applications of Urban Modeling Using Vegetation-Impervious Surface-Soil and Linear Spectral Mixture analysis in Non-Western Counties
Creators: name: Gaw, Caleb Emir
Publisher: name: George Mason University
Year: 2013
Subjects: subject: V-I-S Urban Modeling
subject: Spectural mixture analysis
subject: Vegetation, impervious surface and soil modeling

description: Developing accurate methodologies and models for using remotely sensed data is important in examining and understanding urban areas. Just as sensor types have evolved over time, the techniques and methods for modeling urban areas have been in constant development. In particular, there has been much development over the last 20 years increasing the efficiency and accuracy of the Vegetation – Impervious Surface – Soil (V-I-S) Urban model purposed by Ridd in 1995, through spectral mixture analysis. While many works have shown how to reduce errors within these processes and increase the accuracy of their results over their respective study areas, a fundamental question remains: are these models and techniques applicable to other urban areas outside of their study area? This work will address the logical development of the V-I-S urban model through spectral mixture analysis with the application to urban areas outside of western developed countries. The results will indicate that advances in spectral mixture analysis do increase the accuracy of depicting Vegetation, Impervious Surfaces and Soil, but that the V-I-S model does not accuracy accurately and consistently depict urban areas across the globe.
THE HORMETIC ROLE OF REDOX-ACTIVE POLYPHENOLS IN HUMAN HEALTH AND DISEASE
Creators: name: TEIXEIRA, José Teixeira
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Polyphenols are well-known antioxidant molecules, which present different mechanisms at several subcellular compartments.
Polyphenols, in its oxidized quinone form, may act as potent regulators of the cellular redox status.
Mitochondria, the cell’s powerhouse, adapt to environmental factors by producing effectors that activate multiple pathways related to oxidative stress balance.
Targeting mitochondria with therapeutic agents is an effective therapeutic strategy in human health and disease.
Re-designing natural products and improving intracellular addressing can be a promising strategy to improve the cellular antioxidant status and contribute to decrease oxidative stress.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
External Images to Heatplots
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2021
Subjects: R
plot

description: Dr. Mowinckel's blog: I've written posts before about adding images to ggplot, but in those cases I used the `annotate_custom` function, and loops. This procedure works pretty well, and its been a life saver for me in many places where I do this sort of plotting.
ПСИХОЛОГІЧНИЙ СТАН МЕДИЧНИЙ ПРАЦІВНИКІВ ПІД ЧАС ПАНДЕМІЇ COVID-19: МЕТА-АНАЛІЗ The psychological state of healthcare workers during the pandemic of covid-19: meta-analysis
Creators: name: МАЦ ОКСАНА
Publisher: name: Zenodo
Year: 2022

description: ПСИХОЛОГІЧНИЙ СТАН МЕДИЧНИЙ ПРАЦІВНИКІВ ПІД ЧАС ПАНДЕМІЇ COVID-19: МЕТА-АНАЛІЗ The psychological state of healthcare workers during the pandemic of covid-19: meta-analysis МАЦ ОКСАНА  MATS Oksana Полтавський державний медичний університет (м. Полтава), студентка медичного факультету № 1, 2-го курсу
title: Gastronomy in the Gallery
Creators: name: Rinalducci, Jenna
name: Sheehan, Sarah
name: Irvin, Sarah
Publisher: name: Fenwick Gallery, George Mason University Libraries
Year: 2015
Subjects: subject: Visual art
subject: Artists' books
subject: Cooking
subject: Eating
subject: Gastronomy
subject: Cookbook

description: Exhibition Catalog from Gastronomy in the Gallery exhibit at the Fenwick Gallery, George Mason University
description: From the ubiquitous red and white checks of Better Homes & Gardens New Cook Book to the amazing photography found in Modernist Cuisine, cookbooks are so much more than a collection of recipes. Cookbooks provide insight into a culture, a region, a time period or a cuisine. They are timeless and completely outdated, often at the same time. Sometimes they are not even books. Highlighting the unique collection of cookbooks, Gastronomy in the Gallery is a brief tour of this distinctive cultural and social art form. The resources featured in the exhibit come from the circulation collection, rare and historical items from Special Collections & Archives, and the growing artists’ books collection of the University Libraries. We hope this exhibit inspires, educates, and even leaves you a bit hungry.
The Impact of Viewing Distance and Proprioceptive Manipulations on a Virtual Reality Based Balance Test
Creators: name: Teaford, Max
name: J. Mularczyk, Zachary
name: Gernon, Alannah
name: M. Merfeld, Daniel
Publisher: name: Brill Online
Year: 2024
Subjects: classificationCode: 520406
subject: Sensory processes, perception and performance

description: Our ability to maintain our balance plays a pivotal role in day-to-day activities. This ability is believed to be the result of interactions between several sensory modalities including vision and proprioception. Past research has revealed that different aspects of vision including relative visual motion (i.e., sensed motion of the visual field due to head motion), which can be manipulated by changing the viewing distance between the individual and the predominant visual cues, have an impact on balance. However, only a small number of studies have examined this in the context of virtual reality, and none examined the impact of proprioceptive manipulations for viewing distances greater than 3.5 m. To address this, we conducted an experiment in which 25 healthy adults viewed a dartboard in a virtual gymnasium while standing in narrow stance on firm and compliant surfaces. The dartboard distance varied with three different conditions of 1.5 m, 6 m, and 24 m, including a blacked-out condition. Our results indicate that decreases in relative visual motion, due to an increased viewing distance, yield decreased postural stability — but only with simultaneous proprioceptive disruptions.
EFFECT OF POLYPHENOLS ON NUTRIENT UPTAKE BY BREAST CANCER CELLS:
A NEW POTENTIAL THERAPEUTIC APPROACH?
Creators: name: MARTEL, Fátima
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: One of the cancer molecular hallmarks is a deviant energetic metabolism, known as the Warburg effect, whereby the rate of glucose uptake is significantly increased and a high rate of glycolysis and lactic acid production occurs even when oxygen is present.
Accordingly, GLUT1 and MCT1, which are the main glucose and lactate membrane transporters in cancer cells, respectively, have been proposed as oncogenes and are currently seen as potential therapeutic targets in cancer treatment. Polyphenols are associated with a protective role against cancer. In relation to breast cancer, several mechanisms of action of polyphenols are known to contribute to their anticarcinogenic effect, including modulation of intracellular signaling, induction of apoptosis or epigenetic alterations. Additionally, several polyphenols are able to inhibit glucose transport in breast cancer cell lines; interestingly enough, an association between inhibition of glucose cellular uptake and their anticarcinogenic effect has been described. Also, some polyphenols are able to inhibit lactate transport. Importantly, some polyphenols behave as inhibitors of both glucose and lactate cellular uptake by breast cancer cells.
These compounds are thus very interesting in the context of a chemopreventive effect, because they deplete breast cancer cells of their two most important energy sources. So, the antimetabolic effect of polyphenols should be regarded as a mechanism of action contributing to their chemopreventive/chemotherapeutic potential in relation to breast cancer.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Adding giscus to your blogdown site
Creators: name: Athanasia Monika Mowinckel
Publisher: name: Zenodo
Year: 2021
Subjects: b
l
o
g
d
w
n

description: Dr. Mowinckel's blog: This is going to be a short one. I have been wanting to change my comment section from disqus to utterances for a long while, but have been postponing. Or procrastinating… with me, its usually the latter. I'm not going to go into details of why I wanted to move away from disqus, [others](https://fatfrogmedia.com/delete-disqus-comments-wordpress/) have written better about it that I ever could.
title: A Tantric Understanding of Human Potential: The Bodies of a Buddha, The Path of Attainment, and Their Relevance to Tibetan Self-Immolation
Creators: name: Eskridge, Mark David
Publisher: name: George Mason University
Year: 2019
Subjects: subject: Self-immolation
subject: Tibetan
subject: Buddhism
subject: Tibet
subject: Tantra
subject: Vajrayana

description: This thesis examines the tragedy of Tibetan self-immolation through the perspective of Tantric Buddhism’s understanding of human potential. Such a perspective includes three topics that formulate the individual chapters in this work. They are (1) the result of the tantric path in the form of the bodies of a buddha. (2) The basis of purification in the form of the human body’s mental and physical properties, which tantric aspirants manipulate to produce an enlightened mind and body, and (3) the path—or the specific sequence of yogas—that culminates in the attainment of complete buddhahood. Altogether, these topics emphasize the profound potential of human life, and its ability to generate an altruistic, eternal, and god-like embodiment of enlightenment. Thus, this thesis argues that—when understood from the viewpoint of tantra—the sacrifice of self-immolation has a deeper and more significant meaning than it initially appears.
NATURAL AND BIOINSPIRED POLYPHENOLS WITH ANTIOXIDANT PROPERTIES FOR HEALTH AND FOOD APPLICATIONS
Creators: name: NAPOLITANO,
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The search for novel antioxidants to be used to prevent/control food deterioration or as adjuvants in the treatment of oxidative stress based pathologies has recently spurred considerable interest. In this connection natural compounds and particularly polyphenols that can be easily obtained from accessible vegetable sources or even agricultural wastes are nowadays extensively investigated. The chemopreventive action exerted by polyphenols belonging to the hydroxycinnamate, catechol, catechin, and stilbene groups against the cellular damages brought about by reactive oxygen species (ROS), but also by the reactive nitrosating/nitrating species (RNS) generated in the acidic environment of the stomach from dietary and endogenous nitrite ions is largely documented. Along these lines the presentation will show: 1) how the most popular polyphenol antioxidants can efficiently act as antinitrosating agents and the trasformations they undergo further to reaction with RNS.1 2) how the potential antinitrosating/antioxidant potential of natural polyphenols may be enhanced by conjugation with biological thiols or by other bioinspired trasformations.2 Examples will also be provided of the uses of polymers obtained by biomimetic oxidation of natural phenols as stabilizing additives of polyethylene for packaging3 and as osteogenesis promoters in biocompatible polylactic acid biomaterials.4 Characterization of the reducing and free radical scavenging properties of a series of polymers from natural phenols (e.g. ferulic acid, caffeic acid and pyrogallol) provided a rationale to tailor the properties of these materials. The survey will include examples of natural polyphenolic pigments from food5 or wastes6 showing marked antioxidant properties and will illustrate the preliminary evaluation of their activity following simulated digestion processes.5
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
title: Manioc :
title: Principes directeurs pour la conduite de l’examen de la distinction, de l’homogénéité et de la stabilité.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Plants
New Varieties of Plants
Cassava

description: Ces principes directeurs (“principes directeurs d’examen”) visent à approfondir les principes énoncés dans l’introduction générale (document TG/1/3) et dans les documents TGP qui s’y rapportent afin de donner des indications concrètes détaillées pour l’harmonisation de l’examen de la distinction, de l’homogénéité et de la stabilité (DHS) et, en particulier, à identifier des caractères convenant à l’examen DHS et à la production de descriptions variétales harmonisées.
ROSEMARY EXTRACT: RECENT ADVANCES AND PERSPECTIVES - CARNOSIC ACID STIMULATES SKELETAL MUSCLE CELL GLUCOSE UPTAKE VIA AMPK ACTIVATION
Creators: name: TSIANI, Evangelia Litsa
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Compounds that increase the activity of the energy sensor AMP-activated kinase (AMPK) have the potential to regulate blood glucose levels. Rosemary extract (RE) has been reported to activate AMPK and reduce blood glucose levels in vivo.
In the present study, we measured the levels of the polyphenol carnosic acid (CA) in RE and examined the effects and the mechanism of action of CA on glucose transport system in muscle cells.
High performance liquid chromatography (HPLC) was used to measure the levels of CA in RE. Parental and GLUT4myc or GLUT1myc overexpressing L6 rat myotubes were used. Glucose uptake was assessed using [3H]-2-deoxy-D-glucose. Total and phosphorylated levels of Akt and AMPK were measured by immunoblotting. Plasma membrane GLUT4myc and GLUT1myc levels were examined using a GLUT translocation assay.
At concentrations found in rosemary extract, CA stimulated glucose uptake in L6 myotubes. At 2.0 μM CA a response (226±9.62% of control, p<0.001), similar to maximum insulin (201±7.86%, p<0.001) and metformin (213±10.74%, p<0.001) was seen. Insulin sensitivity was increase by CA. Akt phosphorylation was not affected by CA while AMPK phosphorylation was increased and the CA-stimulated glucose uptake was significantly reduced by the AMPK inhibitor compound C. Plasma membrane GLUT4 or GLUT1 glucose transporter levels were not affected by CA.

Our study is the first to show increased muscle cell glucose uptake and AMPK activation by low CA concentrations, found in rosemary extract, indicating that CA may be responsible for the anti-hyperglycemic properties of rosemary extract seen in vivo.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
POLYPHENOLS AS PROTECTIVE AGENTS AGAINST NEUROTOXICITY AND NEURODEGENERATION: THE CASE OF TEA POLYPHENOLS
Creators: name: ALVES, Marco G.
name: ALMEIDA, Susana
name: NUNES, Ana R.
name: SOUSA, Mário
name: MOREIRA, Paula I.
name: OLIVEIRA, Pedro F
name: SILVA, Branca M
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Europe has the highest proportion of older persons in the World. As population ages, it is imperative to find new strategies to avoid or counteract the effects of the incurable neurodegenerative diseases, which already represent a great financial and emotional burden for health care systems, patients, and their families. In this talk, Branca Silva (PhD) will discuss whether polyphenols obtained from diet or food supplements constitute an effective and low-cost strategy to prevent or treat neurodegeneration and neurotoxicity. Special focus will be given to the recent works of her research team about the beneficial effects to the brain of the regular consumption of white tea (Camellia sincensis L.) and its polyphenols. She will also highlight the safety, mechanisms of action, and the current and future relevance of polyphenols in the prevention and therapy of neurodegenerative disorders.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
FERMENTATION OF BIOACTIVE SOLID LIPID NANOPARTICLES BY HUMAN GUT MICROBIOTA
Creators: name: MADUREIRA, Raquel
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Solid lipid nanoparticles (SLN) can be used for the oral delivery of phenolic compounds in order to protect them from the harsh conditions of digestion and improve their bioavailability in the intestinal epithelium. Recently, the production and characterization of SLN loaded with rosmarinic acid and herbal extracts was performed for future use as functional food ingredients. On the other hand, a hot topic of the moment is the knowledge that diet components have a huge impact on gut microbiota viability and metabolic activity. Hence, this communication concerns the study of the effect of SLN and released phenolic compounds on gut microbiota.
I will make an overview on the results of the fermentations in anaerobic batch cultures using volunteer human faeces during 48h. The impact of these phenolic compounds free and encapsulated in SLN on the main gut bacterial groups population and metabolic activities will be discussed.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)