cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Impact of Credit Shock on Output and Price in Case Of Ethiopia: SVAR Approach
Creators: name: Tesfaye, Mawek
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2014

description: Using the Structural Vector Autoregression (SVAR) method, this paper analyses the impact of domestic credit shock on Ethiopian economy for the period 1998 to 2013 using quarterly data. Totally six variables are included in our VAR model, four from domestic economy and two from external economy. A number of restrictions were imposed on the contemporaneous relationship of variables to identify the unique dynamic response of inflation and output to the credit innovations. As a result, these shocks were used to generate the structural impulse response and forecast error variance decomposition functions for assessing the dynamic impacts of credit shock on country's real gross domestic product and CPI. The impulse response shows that positive credit shock affect CPI positively for long period of time (about five year)and affect real GDP negatively at the beginning (output puzzle) and then positively after third quarter. Whereas, variance decomposition found that the own innovation of domestic variables, except domestic credit, has the highest proportion both in short-term and long-term forecast error. Innovations of CPI take the highest proportion in explaining forecast error of domestic credit relative to other endogenous variables. Based on the find of the study policy implication forwarded are, taking into account the relative impact of credit shock on output and price monetary policy can stimulate output and stabilize price through instruments that affect credit of banking system. Key words: Ethiopia, Structural VAR, Domestic Credit, Output and Price
Horizon Instability of Extremal Kerr Black Holes: Nonaxisymmetric Modes and Enhanced Growth Rate
Creators: name: Casals, Marc
name: Gralla, Samuel E.
name: Zimmerman, Peter
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that the horizon instability of the extremal Kerr black hole is associated with a singular branch point in the Green function at the superradiant bound frequency. We study generic initial data supported away from the horizon and find an enhanced growth rate due to nonaxisymmetric modes. The growth is controlled by the conformal weight of each mode. We speculate on connections to near-extremal black holes and holographic duality.
description: 7 pages. 1 figure
Universality and critical behavior of the dynamical Mott transition in a system with long-range interactions
Creators: name: Rademaker, Louk
name: Vinokur, Valerii V.
name: Galda, Alexey
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study numerically the voltage-induced breakdown of a Mott insulating phase in a system of charged classical particles with long-range interactions. At half-filling on a square lattice this system exhibits Mott localization in the form of a checkerboard pattern. We find universal scaling behavior of the current at the dynamic Mott insulator-metal transition and calculate scaling exponents corresponding to the transition. Our results are in agreement, up to a difference in universality class, with recent experimental evidence of dynamic Mott transition in a system of interacting superconducting vortices.
description: 6 pages, 5 figures
Search for Muonic Dark Forces at BABAR
Creators: name: Godang, Romulus
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Many models of physics beyond Standard Model predict the existence of light Higgs states, dark photons, and new gauge bosons mediating interactions between dark sectors and the Standard Model. Using a full data sample collected with the BABAR detector at the PEP-II $e^+e^-$ collider, we report searches for a light non-Standard Model Higgs boson, dark photon, and a new muonic dark force mediated by a gauge boson ($Z'$) coupling only to the second and third lepton families. Our results significantly improve upon the current bounds and further constrain the remaining region of the allowed parameter space.
description: Contributed to the Proceedings of the XLVI International Symposium on Multiparticle Dynamics, Jeju island, South Korea, 2016. This work was supported by the U.S. Department of Energy
The analysis and design of pile shafts in weak rock
Creators: name: Seidel, Julian P.
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Households' Willingness to Pay For Environmental Practices: An Implication of Eco-Labeling For Leather Products in Ethiopia
Creators: name: Gebreselassie, Solomon
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2007

description: Eco-labels are becoming important market based instruments to influence the behavior of consumers and industry in favor of environmentally-friendly products. This study examined households' willingness to pay (WTP) a premium for environmental attributes of leather products in a hypothetical market. An eco-labeling scheme is used to differentiate leather products. Data was collected using two-stage sampling. First purposive sampling is used to select two kebeles based on their relative distance from the pollution source and polluted river. Next 300 households are selected using systematic random sampling. Descriptive statistics and an ordered probit model are used to analyse the data set. The result revealed that the majority of the households agreed that environmental pollution caused by conventional leather processing is a problem to the livelihood of the people. Besides, almost all respondents acknowledged the importance of the shift of production techniques from conventional to environmentally friendly production techniques. With regard to eco-labeling scheme, almost all respondents supported the programme. About 75% of the respondents are willing to pay a premium for environmental practices. The results suggest that monthly income, family size and location significantly affect willingness to pay. Finally, the findings in this study showed that there is a market for ecolabeled leather products. Therefore eco-labeling could be used as an important market instrument to complement mandatory laws and regulation for environmental protection.
Structurally disordered C-terminal residues of GTP cyclohydrolase II are essential for its enzymatic activity
Creators: name: Yadav, Savita
name: Shinde, Ranajit Nivrutti
name: Singh, Suruchi
name: Karthikeyan, Subramanian
name: Singh, Balvinder
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: GTP cyclohydrolase II (GCHII) is one of the rate limiting enzymes in riboflavin biosynthesis pathway and is shown to be a potential drug target for most of the pathogens. Previous biochemical and structural studies have identified the active site residues and elucidated the steps involved in the catalytic mechanism of GCHII. However, the last ∼20–25 C-terminal residues of GCHII remains unstructured in all the crystal structures determined to date and their role in the catalytic activity, if any, remains elusive. Therefore, to understand the role of these unstructured C-terminal residues, a series of C-terminal deletion mutants of GCHII from Helicobacter pylori (hGCHII) were generated and their catalytic activity was compared with its wild-type. Surprisingly, none of the C-terminal deletion mutants shows any enzymatic activity indicating that these are essential for GCHII function. To get additional insights for such loss of activity, homology models of full-length and deletion mutants of hGCHII in complex with GTP, Mg2+, and Zn2+ were generated and subjected to molecular dynamics simulation studies. The simulation studies show that a conserved histidine at 190th position from the unstructured C-terminal region of hGCHII interacts with α-phosphate of GTP. We propose that His-190 may play a role in the hydrolysis of pyrophosphate from GTP and in releasing the product, DARP. In summary, we demonstrate that the unstructured C-terminal residues of GCHII are important for its enzymatic activity and must be considered during rational drug designing. Communicated by Ramaswamy H. Sarma
Engineering a multi epitope vaccine against SARS-CoV-2 by exploiting its non structural and structural proteins
Creators: name: Rajput, Vikrant Singh
name: Sharma, Ritika
name: Kumari, Anchala
name: Vyas, Nidhi
name: Prajapati, Vijay
name: Grover, Abhinav
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: SARS-CoV-2, the causative agent behind the ongoing pandemic exhibits an enhanced potential for infection when compared to its related family members- the SARS-CoV and MERS-CoV; which have caused similar disease outbreaks in the past. The severity of the global health burden, increasing mortality rate and the emergent economic crisis urgently demands the development of next generation vaccines. Amongst such emergent next generation vaccines are the multi-epitope subunit vaccines, which hold promise in combating deadly pathogens. In this study we have exploited immunoinformatics applications to delineate a vaccine candidate possessing multiple B and T cells epitopes by utilizing the SARS-CoV-2 non structural and structural proteins. The antigenicity potential, safety, structural stability and the production feasibility of the designed construct was evaluated computationally. Furthermore, due to the known role of human TLR-3 immune receptor in viral sensing, which facilitates host cells activation for an immune response, the vaccine construct was examined for its binding efficiency using molecular docking and molecular dynamics simulation studies, which resulted in strong and stable interactions. Finally, the immune simulation studies suggested an effective immune response on vaccine administration. Overall, the immunoinformatics analysis advocates that the proposed vaccine candidate is safe and immunogenic and therefore can be pushed as a lead for in vitro and in vivo investigations. Communicated by Ramaswamy H. Sarma
The GlueX DIRC Project
Creators: name: Stevens, Justin
name: Barbosa, Fernando
name: Bessuille, Jason
name: Chudakov, Eugene
name: Dzhygadlo, Roman
name: Fanelli, Cristiano
name: Frye, John
name: Hardin, John
name: Kelsey, Jim
name: Patsyuk, Maria
name: Schwartz, Carsten
name: Schwiening, Jochen
name: Shepherd, Matthew
name: Whitlatch, Tim
name: Williams, Michael
Publisher: name: arXiv
Year: 2016
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The GlueX experiment was designed to search for and study the pattern of gluonic excitations in the meson spectrum produced through photoproduction reactions at a new tagged photon beam facility in Hall D at Jefferson Laboratory. The particle identification capabilities of the GlueX experiment will be enhanced by constructing a DIRC (Detection of Internally Reflected Cherenkov light) detector, utilizing components of the decommissioned BaBar DIRC. The DIRC will allow systematic studies of kaon final states that are essential for inferring the quark flavor content of both hybrid and conventional mesons. The design for the GlueX DIRC is presented, including the new expansion volumes that are currently under development.
description: 8 pages, 6 figures
Überlegungen zu Sprache und Sitz im Leben des Toratargums 4 Q Tg Lev (4 Q 156), sein Verhältnis zu Targum Onkelos
Creators: name: Angerstorfer, Andreas
Publisher: name: Biblische Notizen
Year: 1970

description: Biblische Notizen, Bd. 55 (1990): Biblische Notizen, Band 55
Application of persuasion principles to a community based travel behaviour change program
Creators: name: Seethaler, Rita Katharina
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Exploring multi-target inhibitors using in silico approach targeting cell cycle dysregulator–CDK proteins
Creators: name: Ahmed, Basharat
name: Khan, Sara
name: Nouroz, Faisal
name: Farooq, Umar
name: Khalid, Saba
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Computational Biology

description: Cyclin-dependent kinases (CDKs) belong to a family of multifunctional enzymes that control cell cycle modifications, transcription, and cell proliferation. Their dysfunctions result in different diseases like cancer making them an important drug target in oncology and beyond. The present study aims at identifying the selective inhibitors for ATP binding site in CDK proteins (CDK1, CDK2, CDK4, and CDK5) following a multi-target drug designing approach. Significant challenges lie in identifying the selective inhibitor for the ATP binding site as this region is highly conserved in all protein kinases. Molecular docking coupled with molecular dynamics simulation and free energy of binding calculations (MMPBSA/MMGBSA) were used to identify the potent competitive ATP binding site inhibitors. All the four proteins were docked against the library of drug-like compounds and the outcomes of the docking study were further analyzed by Molecular dynamics (total of 6μs) and MMPB/GBSA techniques. Five different inhibitors for structurally distant protein kinases, i.e. CDK1, CDK2, CDK4, and CDK5 are identified with the binding energy (ΔGbind-PB) in the range −18.24 to −28.43Kcal/mol. Mechanistic complexities associated with the binding of the inhibitor are unraveled by carefully analyzing the MD trajectories. It is observed that certain residues (Lys33, Asp127, Asp145, Tyr15, Gly16, Asn144) and regions are critical for the retention of inhibitors in active pocket, and significant conformational changes take place in the active site region as well as its neighbor following the entry of the ligand inside active pocket as inferred by RMSD and RMSF. It is observed that LIG3 and LIG4 are the best possible inhibitors as reflected from their high binding energy, interaction pattern, and their retention inside the active pocket. This study will facilitate the process of multi-target drug designing against CDK proteins and can be used in the development of potential therapeutics against different diseases. Communicated by Ramaswamy H. Sarma
Phase stability in multi-cation [alpha]-sialon systems
Creators: name: Seeber, Aaron John
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Settling and rheological behaviour of red mud slurries
Creators: name: Sarmiento, Guillermo
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Gravitational Wave Memory: A New Approach to Study Modified Gravity
Creators: name: Du, Song Ming
name: Nishizawa, Atsushi
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is well known that two types of gravitational wave memory exist in general relativity (GR): the linear memory and the non-linear, or Christodoulou memory. These effects, especially the latter, depend on the specific form of Einstein equation. It can then be speculated that in modified theories of gravity, the memory can differ from the GR prediction, and provides novel phenomena to study these theories. We support this speculation by considering scalar-tensor theories, for which we find two new types of memory: the T memory and the S memory, which contribute to the tensor and scalar components of gravitational wave, respectively. In particular, the former is caused by the burst of energy carried away by scalar radiation, while the latter is intimately related to the no scalar hair property of black holes in scalar-tensor gravity. We estimate the size of these two types of memory in gravitational collapses, and formulate a detection strategy for the S memory, which can be singled out from tensor gravitational waves. We show that (i) the S memory exists even in spherical symmetry, and is observable under current model constraints, and (ii) while the T memory is usually much weaker than the S memory, it can become comparable in the case of spontaneous scalarization.
description: 5 pages, 4 figures
Rashba-Dresselhaus spin-splitting in the bulk ferroelectric oxide BiAlO$_3$
Creators: name: da Silveira, Luiz Gustavo Davanse
name: Barone, Paolo
name: Picozzi, Silvia
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: It has been recently suggested that the coexistence of ferroelectricity and Rashba-like spin-splitting effects due to spin-orbit coupling in a single material may allow for a non-volatile electric control of spin degrees of freedom. In the present work, we compared the structural and ferroelectric properties of tetragonal and rhombohedral phases of ferroelectric BiAlO$_3$ by means of density-functional calculations. In both phases, we carefully investigated Rashba and Dresselhaus effects, giving rise to spin-splitting in their bulk electronic structure, particularly near the conduction band minimum, supplementing our first-principles results with an effective $ k\cdot p$ model analysis. The full reversal of the spin texture with ferroelectric polarization switching was also predicted. BiAlO$_3$ can therefore be considered as the first known oxide to exhibit a coexistence of ferroelectricity and Rashba-Dresselhaus effects.
description: 8 pages, 5 figures
Aperture-free star formation rate of SDSS star-forming galaxies
Creators: name: Puertas, S. Duarte
name: Vilchez, J. M.
name: Iglesias-Paramo, J.
name: Kehrig, C.
name: Perez-Montero, E.
name: Rosales-Ortega, F. F.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Large area surveys with a high number of galaxies observed have undoubtedly marked a milestone in the understanding of several properties of galaxies, such as star-formation history, morphology, and metallicity. However, in many cases, these surveys provide fluxes from fixed small apertures (e.g. fibre), which cover a scant fraction of the galaxy, compelling us to use aperture corrections to study the global properties of galaxies. In this work, we derive the current total star formation rate (SFR) of Sloan Digital Sky Survey (SDSS) star-forming galaxies, using an empirically based aperture correction of the measured $\rm Hα$ flux for the first time, thus minimising the uncertainties associated with reduced apertures. All the $\rm Hα$ fluxes have been extinction-corrected using the $\rm Hα/Hβ$ ratio free from aperture effects. The total SFR for $\sim$210,000 SDSS star-forming galaxies has been derived applying pure empirical $\rm Hα$ and $\rm Hα/Hβ$ aperture corrections based on the Calar Alto Legacy Integral Field Area (CALIFA) survey. We find that, on average, the aperture-corrected SFR is $\sim$0.65dex higher than the SDSS fibre-based SFR. The relation between the SFR and stellar mass for SDSS star-forming galaxies (SFR--$\rm M_\star$) has been obtained, together with its dependence on extinction and $\rm Hα$ equivalent width. We compare our results with those obtained in previous works and examine the behaviour of the derived SFR in six redshift bins, over the redshift range $\rm 0.005 \leq z\leq 0.22$. The SFR--$\rm M_\star$ sequence derived here is in agreement with selected observational studies based on integral field spectroscopy of individual galaxies as well as with the predictions of recent theoretical models of disc galaxies.
Market Efficiency of the Ethiopia Commodity Exchange: The Case of Export Coffee Trading
Creators: name: Hussein, Abdurezack
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2010

description: Despite the pivotal role of agriculture in the Ethiopian economy, the sector's development is highly constrained by infrastructural and institutional problems. To tackle part of the institutional problem, spot-trading Ethiopia Commodity Exchange (ECX) was established with a vision to revolutionize the country's agriculture through an efficient, dynamic, forward-looking and orderly marketing system. This thesis is probably the first of its type to study the market efficiency of the ECX in trading its major commodity, namely export coffee. The Efficient Market Hypothesis (EMH) is widely used in market efficiency studies. This thesis tested the weak form of EMH using the ADF, the Lo-MacKinlay variance ratio and the BDS tests for random walk to study the price formation behavior of washed and unwashed export coffees traded in the exchange for 16 months. The post estimation tests on the ADF regression showed that ADF is inappropriate to use for the purpose for the study. The test for normality of observations also showed that parametric tests for random walk are not appropriate to study most of the prices series. The results from the non-parametric Variance Ratio and BDS tests, however, consistently showed that there are both linear and non-linear dependencies in the price series of both commodities and there is no observable trend towards efficiency. To further strength the results, the Spearman's Rank Correlation coefficient results have supported the presence of a persistent and strong dependencies in the price series. The result thus entails that, within the study period, ECX is weak-form inefficient and there is possibilities of taking trading position that potentially offer traders excess profit using the predictability in the price series. The result, however, is not surprising given the presence of price band limits, the infancy of the Exchange and most importantly the nature of the trading (spot-based) in ECX. To address the market efficiency problem and other crucial issues, the Exchange has to shift to futures based trading. As such shifts cannot be made overnight, some measures are recommended that can be implemented alongside the institutional development process in order to make the existing system a more efficient one.
In silico assessment of dehalogenase from Bacillus thuringiensis H2 in relation to its salinity-stability and pollutants degradation
Creators: name: Oyewusi, Habeebat Adekilekun
name: Huyop, Fahrul
name: Wahab, Roswanira Abdul
name: Hamid, Azzmer Azzar Abdul
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: Increased scientific interest has led to the rise in biotechnological uses of halophilic and halotolerant microbes for hypersaline wastewater bioremediation. Hence, this study performed molecular docking, molecular dynamic (MD) simulations, and validation by Molecular Mechanic Poisson-Boltzmann Surface Area (MM-PBSA) calculations on the DehH2 from Bacillus thuringiensis H2. We aimed to identify the interactions of DehH2 with substrates haloacids, haloacetates, and chlorpyrifos under extreme salinity (35% NaCl). MD simulations revealed that DehH2 preferentially degraded haloacids and haloacetates (−6.3 to −4.7 kcal/mol) by forming three or four hydrogen bonds to the catalytic triad, Asp125, Arg201, and Lys202. Conversely, chlorpyrifos was the least preferred substrate in both MD simulations and MM-PBSA calculations. MD simulation results ranked the DehH2-L-2CP complex (RMSD □0.125−0.23 nm) as the most stable while the least was the DehH2-chlorpyrifos complex (RMSD 0.32 nm; RMSF 0.0 − 0.29). The order of stability was as follows: DehH2-L-2CP > DehH2-MCA > DehH2-D-2CP > DehH2-3CP > DehH2-2,2-DCP > DehH2-2,3-DCP > DehH2-TCA > DehH2-chlorpyrifos. The MM-PBSA calculations further affirmed the DehH2-L-2CP complex's highest stability with the lowest binding energy of −45.14 kcal/mol, followed closely by DehH2-MCA (−41.21 kcal/mol), DehH2-D-2CP (−31.59 kcal/mol), DehH2-3CP (−30.75 kcal/mol), DehH2-2,2- DCP (−29.72 kcal/mol), DehH2-2,3-DCP (−22.20 kcal/mol) and DehH2-TCA (−18.46 kcal/mol). The positive binding energy of the DehH2-chlorpyrifos complex (+180.57 kcal/mol) proved the enzyme's non-preference for the substrate. The results ultimately illustrated the unique specificity of the DehH2 to degrade the above-said pollutants under a hypersaline condition. Communicated by Ramaswamy H. Sarma
A Dynamic Monetary Model of Ethiopia
Creators: name: Mamma, Zekarias
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2003

description: The paper has developed a very small monetary model of the Ethiopian economy. The model is made up of five behavioral equations linking the monetary sector, aggregate demand and supply, and the external sectors of the economy. The motivation for the study is derived from the desire to present a model that would help us analyze the behavior of key macroeconomic variables in Ethiopia and help us address the effectiveness of stabilization policy. The model was estimated using the cointegration technique.. In all the equations the variables in the long run equations were first tested and found to be cointegrated of order one. The integrated series of variables were then tested for cointegration by the Johnsen Cointegration test. Annual data from 1965/66 to 2001/02 was used to estimate the behavioral equations of the model. Individual equations of the model satisfied a number of statistical diagnostic tests and the model as a whole was found to be stable with very good within sample tracking performance. Two dynamic counterfactual simulations were carried out using the model. The first simulation tried to assess what the performance of the Ethiopian economy would have been without the 1992 devaluation. The results indicate that without the devaluation, the performance of the external sector would have been very poor. The overvalued exchange rate would have resulted in a deteriorated trade balance, on average by 26 percent per year. The second policy experiment considered the effect of sustained credit contraction. The results seem to indicate that sustained domestic credit contraction could reduce output with very little improvement in the net foreign asset position of the economy. The policy implications that could be derived from the study are that overvalued exchange rate adversely affects economic performance. This empirical finding is similar with the findings of Ghura and Green(1993). Another important policy implication of the study is that policies accompanying devaluation i.e. such as domestic credit restraint should bescrutinized carefully as credit restraint may result in reduced output with out much improvement in external balance of the economy. Keywords: Stabilization policy, Monetary Model, Cointegration, Simulations, Devaluation, Monetary Restraint
Dynamic response of reinforced concrete structures with softening behavior
Creators: name: Sanjayan, G.
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Galaxy groups in the 2MASS Redshift Survey
Creators: name: Lu, Yi
name: Yang, Xiaohu
name: Shi, Feng
name: Mo, H. J.
name: Tweed, Dylan
name: Wang, Huiyuan
name: Zhang, Youcai
name: Li, Shijie
name: Lim, S. H.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A galaxy group catalog is constructed from the 2MASS Redshift Survey (2MRS) with the use of a halo-based group finder. The halo mass associated with a group is estimated using a `GAP' method based on the luminosity of the central galaxy and its gap with other member galaxies. Tests using mock samples shows that this method is reliable, particularly for poor systems containing only a few members. On average 80% of all the groups have completeness >0.8, and about 65% of the groups have zero contamination. Halo masses are estimated with a typical uncertainty $\sim 0.35\,{\rm dex}$. The application of the group finder to the 2MRS gives 29,904 groups from a total of 43,246 galaxies at $z \leq 0.08$, with 5,286 groups having two or more members. Some basic properties of this group catalog is presented, and comparisons are made with other groups catalogs in overlap regions. With a depth to $z\sim 0.08$ and uniformly covering about 91% of the whole sky, this group catalog provides a useful data base to study galaxies in the local cosmic web, and to reconstruct the mass distribution in the local Universe.
description: 15 pages, 15 figures, accepted by ApJ
Government Budget Defect, Money Supply, Inflation and Policy Implication
Creators: name: Abdi, Jemal
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2007

description: The objective of the study is to examine the causal relationship between budget deficit , Money supply and Inflation in Ethiopia. Aghevli and Khan(1978) model was used in analyzing the Ethiopian annual data from 1974-2005. In the model there are two period of analysis :period I from 1974-1991 where there is regulation of wages and prices and period II from 1992-2005 where there is structural adjustement programs at the beginning of the period and free market economy used as state's policy. Instrumental Variables(Two-Stage Least Squares) estimation methods was used to analyse the short-run dynamics and long run relationships among budget deficit, Money Supply and Inflation. The Findings of the study are: In period I inflation is significant in the explanation of current price level ,the coefficients of Government Expenditure,Government Revenue equations are insignificant in the short-run .Thus we only draw conclusion and policy recommendation based on the equation of period II . Two-way causation between money supply and inflation was demonstrated. Government expenditures adjust faster than revenue ,as the mean lag of government expenditure is less than the mean lag of government revenue,that is,during inflation the real revenue fall faster than real government expenditures due to long lags in the collection of taxes. The monetarist paradigm of sustained inflation resulting from budgetary deficit is empirically confirmed.The policy implication is that without emplementing effective monetary and fiscal policies,it is difficult to see macroeconomic stability and good economic performance in the country. As a recommendation ,the Minitry of Finance and Economic Development,Ministry of Revenue and National Bank of Ethiopia should coordinate their effort to impelement the monetary and fiscal policies to reduce the larege budget deficit,control the inflation and reduce lags in the collection of taxes,improving tax performce and efficiency in tax administration.
Determinants of Export of Growth Rate in Ethiopia 1980-2010: Co-co-integration and Error Correction model Analysis
Creators: name: Hailu, Kiros
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2012

description: The study aimed at identifying the major determinants of export growth rate which have been a matter of argument in Ethiopia and Africa as a whole for a long period of time. The paper empirically examined the export growth rate and its major factors in the Ethiopian context using time series data for the period 1980-2010 collected from ERCA, NBE, UNCTAD, and WEO by employing co integration and error correction model which is previous used by Musinguzi et al (2000) was adopted for this study. Estimation result of the model shows that the relationship between the foreign price level, and terms of trade with the export growth rate are positive and negative which are statistically significant respectively. The gross domestic product also positive and significant but it is not strong. So the foreign price level, Terms of trade and gross domestic product appear to be major determinants, whereas the real exchange rate and FDI have no statistically significant effect on Ethiopia's export growth rate. Therefore to promote the export growth rate understanding and revising of the country's export structure, situations and other policies related to the sector is necessary. Keywords: Ethiopia; export; growth rate; determinants; error correction model.
title: Entwicklung eines Multichannel Social Media Marketingtools basierend auf Atlassian Produkten
Creators: name: Yilmaz, Damla Naz
Publisher: name: Hochschulbibliothek der Technischen Hochschule Köln
Year: 2023
Subjects: subject: 000 Allgemeines, Informatik, Informationswissenschaft

description: Heutzutage ist das Internet, wie die sozialen Netzwerke ein fester Bestandteil unserer So nutzen Unternehmen in dem Kommunikationszeitalter die Netzwerke um in diesen Plattformen mit den Nutzern zu kommunizieren. Hierbei ist das Ziel dieser Bachelorarbeit zu untersuchen in wie weit man eine Erweiterung entwickeln kann um diese Ziele zu erreichen. Dabei soll im Rahmen dieser Arbeit eine prototypische Implementierung stattfinden, um die Entwicklung eines Multichannel Social Media Marketingtools basierend auf Atlassian Produkten zu ermöglichen. Die Arbeit gibt zunächst einen Überblick der wichtigsten Grundlagen. Danach wird mit einer Analyse die Anforderungen an den Prototypen erhebt und ausgewertet , sowie eine Marktanalyse durchgeführt. Darauf folgt die Konzeption, wie die Implementierung des Prototyps, was im Anschluss mit einem Test für die Gebrauchstauglichkeit ergänzt wird.
Variable stars and stellar populations in Andromeda XXV: III. A central cluster or the galaxy nucleus?
Creators: name: Cusano, Felice
name: Garofalo, Alessia
name: Clementini, Gisella
name: Cignoni, Michele
name: Federici, Luciana
name: Marconi, Marcella
name: Ripepi, Vincenzo
name: Musella, Ilaria
name: Testa, Vincenzo
name: Carini, Roberta
name: Faccini, Marco
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present B and V time-series photometry of Andromeda XXV, the third galaxy in our program on the Andromeda's satellites, that we have imaged with the Large Binocular Cameras of the Large Binocular Telescope. The field of Andromeda XXV is found to contain 63 variable stars, for which we present light curves and characteristics of the light variation (period, amplitudes, variability type, mean magnitudes, etc.). The sample includes 58 RR Lyrae variables (46 fundamental-mode $-$ RRab, and 12 first-overtone $-$RRc, pulsators), three anomalous Cepheids, one eclipsing binary system and one unclassified variable. The average period of the RRab stars ($\langle Pab \rangle$ = 0.60 $σ=0.04$ days) and the period-amplitude diagram place Andromeda XXV in the class of the Oosterhoff-Intermediate objects. From the average luminosity of the RR Lyrae stars we derive for the galaxy a distance modulus of (m-M)$_0$=$24.63\pm0.17$ mag. The color-magnitude diagram reveals the presence in Andromeda XXV of a single, metal-poor ([Fe/H]=$-$1.8 dex) stellar population as old as $\sim$ 10-12 Gyr traced by a conspicuous red giant branch and the large population of RR Lyrae stars. We discovered a spherically-shaped high density of stars near the galaxy center. This structure appears to be at a distance consistent with Andromeda XXV and we suggest it could either be a star cluster or the nucleus of Andromeda XXV. We provide a summary and compare number and characteristics of the pulsating stars in the M31 satellites analyzed so far for variability.
description: Updated version accepted for publication in ApJ
Synthesis, dielectric properties, molecular docking and ADME studies of pyrrole-3-ones
Creators: name: Çapan, İrfan
name: Gümüş, Mehmet
name: Gökce, Halil
name: Çetin, Hidayet
name: Sert, Yusuf
name: Koca, İrfan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: A novel series of pyrrole-3-one derivatives were synthesized using furan-3-one derivatives and various aromatic amines. The synthesized compounds were identified by spectral studies such as IR, NMR and HRMS. Dielectric properties of the target compounds were experimentally determined by dielectric spectroscopy in the frequency range of 20 Hz − 1 MHz. The real part of the dielectric constant, dielectric loss tangent and conductivity of the samples were investigated as a function of applied frequency. Dielectric measurements showed Ata7 has the maximum dielectric constant at 1 kHz, while Ata1 has a negative dielectric constant value. When the result is evaluated with theoretical calculations, grain boundaries play an effective role in the experimental observed dielectric constant. Additionally, in this research the pyrrole-3-one derivatives (Ata1-9) were theoretically optimized and over these structures, NMR with GIAO (gauge-independent atomic orbital), UV with TD (time dependent), frontier orbitals (HOMO and LUMO), NLO (nonlinear optical properties) and MEP (molecular electrostatic potential) analysis were carried out. Quantum chemical computations were performed by Density Functional Theory (DFT) using B3LYP functional and 6-311++G (d,p) basis set. Later, the molecular docking analysis between Ata1-9 and two different receptors such as 3RZE and 3TDA was performed using AutoDock Vina program. Lastly, drug-likeness, physicochemical and ADME/T properties of the designed compounds were computed with the help of SwissADME online tool. Communicated by Ramaswamy H. Sarma
Identification of selective LdDHFR inhibitors using quantum chemical and molecular modeling approach
Creators: name: Sharma, Vishnu Kumar
name: Kathuria, Deepika
name: Bharatam, Prasad V.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 60506 Virology

description: Among the various known targets for the treatment of Leishmaniasis, dihydrofolate reductase (DHFR) is an essential target which plays an important role in the folate metabolic pathway. In the current study, pharmacoinformatics approaches including quantum chemistry methods, molecular docking and molecular dynamics simulations have been utilized to identify selective Leishmania donovani DHFR (LdDHFR) inhibitors. Initially, for the design of new LdDHFR inhibitors, a virtual combinatorial library was created by considering various head groups (scaffolds), linkers and tail groups. The scaffolds utilized in the library design were selected on the basis of their proton affinity (PA) estimated using quantum chemical methods, required to make a strong H-bond interaction with negatively charged LdDHFR active site. Later on, molecular docking-based virtual screening was performed to screen the designed library. Selectivity of the chosen hits toward the LdDHFR was established through re-docking in the human DHFR enzyme (HsDHFR). Best five hits were subjected to molecular dynamics (MD) simulations to validate their selectivity as well as stability in LdDHFR. Out of the five hits, four were found to be energetically more favorable and promising for selective binding toward LdDHFR in comparison to HsDHFR. Communicated by Ramaswamy H. Sarma
Doubled Lattice Chern-Simons-Yang-Mills Theories with Discrete Gauge Group
Creators: name: Caspar, Stephan
name: Mesterházy, David
name: Olesen, Therkel Z.
name: Vlasii, Nadiia D.
name: Wiese, Uwe-Jens
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We construct doubled lattice Chern-Simons-Yang-Mills theories with discrete gauge group $G$ in the Hamiltonian formulation. Here, these theories are considered on a square spatial lattice and the fundamental degrees of freedom are defined on pairs of links from the direct lattice and its dual, respectively. This provides a natural lattice construction for topologically-massive gauge theories, which are invariant under parity and time-reversal symmetry. After defining the building blocks of the doubled theories, paying special attention to the realization of gauge transformations on quantum states, we examine the dynamics in the group space of a single cross, which is spanned by a single link and its dual. The dynamics is governed by the single-cross electric Hamiltonian and admits a simple quantum mechanical analogy to the problem of a charged particle moving on a discrete space affected by an abstract electromagnetic potential. Such a particle might accumulate a phase shift equivalent to an Aharonov-Bohm phase, which is manifested in the doubled theory in terms of a nontrivial ground-state degeneracy on a single cross. We discuss several examples of these doubled theories with different gauge groups including the cyclic group $\mathbb{Z}(k)\subset U(1)$, the symmetric group $S_3\subset O(2)$, the binary dihedral (or quaternion) group $\bar{D}_2\subset SU(2)$, and the finite group $Δ(27)\subset SU(3)$. In each case the spectrum of the single-cross electric Hamiltonian is determined exactly. We examine the nature of the low-lying excited states in the full Hilbert space, and emphasize the role of the center symmetry for the confinement of charges. Whether the investigated doubled models admit a non-Abelian topological state which allows for fault-tolerant quantum computation will be addressed in a future publication.
description: 42 pages, 5 figures; Revised version: Corrected typos and updated references
Effect of local anesthetic drug procaine hydrochloride on the conformational stability of bovine hemoglobin: Multi-spectroscopic and computational approaches
Creators: name: Kaushal, Deepak
name: Lal, Hira
name: Ansari, Sameer Shakeel
name: Naqvi, Saeeda
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: The interaction between bovine hemoglobin (BHb) and local anesthetic drug procaine hydrochloride (PCH) was examined by spectroscopic and computational studies. Intrinsic fluorescence analysis explored the ground-state complex formation in the binding of PCH with BHb through static quenching mechanism. The binding constants (Kb) are 29.38 × 103, 22.54 × 103 and 17.99 × 103 M−1 at 288, 298 and 308 K, respectively, and the ratio of BHb:PCH was 1:1 in the interaction mechanism of PCH and BHb. The acquired thermodynamic parameters (ΔH0, ΔG0 and ΔS0) demonstrated that interaction mechanism is spontaneous and enthalpy driven. The van der Waals forces and hydrogen bonding have been played a predominant role in the binding mechanism. The UV-vis spectroscopy validates the ground-state complexation between PCH and BHb and the binding constant (Kb) has been evaluated utilizing Benesi-Hildebrand equation. Fluorescence resonance energy transfer (FRET) results have demonstrated that the distance between donor (BHb) and acceptor (PCH) is very short (2.34 nm) suggesting a significant probability to energy transfer from BHb to PCH. Synchronous fluorescence results revealed that the alteration in the micro-environment of Tyrosine (Tyr) is more than tryptophan (Trp) residues suggesting that PCH molecule is close to Tyr residue. The secondary structure alterations were confirmed by CD, 3-D fluorescence and FT-IR spectroscopic measurements. Moreover, computational analyses further corroborated that PCH molecules are closer to Tyr residues as compared to Trp residues of BHb during the interaction process. The BHb-PCH complexes may contribute to a deeper understanding of the metabolism of drug, blood circulation process and may help to illustrate the relationship between functions and structure of BHb. Communicated by Ramaswamy H. Sarma