cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(3816) Ethel Blanche Scott
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis
Creators: name: Linhoff, Michael W.
name: Potts, Patrick Ryan
name: Deshmukh, Mohanish
name: Wright, Kevin M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Despite the potential of the inhibitor of apoptosis proteins (IAPs) to block cytochrome c–dependent caspase activation, the critical function of IAPs in regulating mammalian apoptosis remains unclear. We report that the ability of endogenous IAPs to effectively regulate caspase activation depends on the differentiation state of the cell. Despite being expressed at equivalent levels, endogenous IAPs afforded no protection against cytochrome c–induced apoptosis in naïve pheochromocytoma (PC12) cells, but were remarkably effective in doing so in neuronally differentiated cells. Neuronal differentiation was also accompanied with a marked reduction in Apaf-1, resulting in a significant decrease in apoptosome activity. Importantly, this decrease in Apaf-1 protein was directly linked to the increased ability of IAPs to stringently regulate apoptosis in neuronally differentiated PC12 and primary cells. These data illustrate specifically how the apoptotic pathway acquires increased regulation with cellular differentiation, and are the first to show that IAP function and apoptosome activity are coupled in cells.
(3818) John Gordon Munro
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
FAK and Paxillin: Regulators of N-Cadherin Adhesion and Inhibitors of Cell Migration?
Creators: name: Schaller, Michael D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: FAK and paxillin are important components in integrin-regulated signaling. New evidence suggests that these two proteins function in crosstalk between cell-matrix and cell-cell adhesions. Further, new insight suggests that under some conditions these proteins inhibit cell migration, in contrast to their established roles in several cell systems as positive regulators of cell adhesion and migration.
Identification of the membrane receptor of a class XIV myosin in Toxoplasma gondii
Creators: name: Mann, Tara
name: Ward, Gary
name: Gaskins, Elizabeth
name: Gilk, Stacey
name: DeVore, Nicolette
name: Beckers, Con
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Apicomplexan parasites exhibit a unique form of substrate-dependent motility, gliding motility, which is essential during their invasion of host cells and during their spread between host cells. This process is dependent on actin filaments and myosin that are both located between the plasma membrane and two underlying membranes of the inner membrane complex. We have identified a protein complex in the apicomplexan parasite Toxoplasma gondii that contains the class XIV myosin required for gliding motility, TgMyoA, its associated light chain, TgMLC1, and two novel proteins, TgGAP45 and TgGAP50. We have localized this complex to the inner membrane complex of Toxoplasma, where it is anchored in the membrane by TgGAP50, an integral membrane glycoprotein. Assembly of the protein complex is spatially controlled and occurs in two stages. These results provide the first molecular description of an integral membrane protein as a specific receptor for a myosin motor, and further our understanding of the motile apparatus underlying gliding motility in apicomplexan parasites.
REDESCRIPTION AND GENERIC STATUS OF PSEUDANTHESSIUS-NEMERTOPHILUS (GALLIEN, 1936), POECILOSTOMATOID COPEPOD ASSOCIATED TO LINEUS-LONGISSIMUS OF COASTS OF THE ENGLISH-CHANNEL
Creators: name: Stock, J. H.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1985

Abstract
New records of bryozoans from Portugal
Creators: name: SOUTO, Javier
name: REVERTER-GIL, Oscar
name: DE BLAUWE, Hans
name: FERNÁNDEZ-PULPEIRO, Eugenio
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2014

description: Unpublished data on 37 bryozoan species collected in different parts of the Portuguese coast are provided. 21 of them are reported from Portugal for the first time. Among them, Sessibugula barrosoi, Smittina jordii and Schizomavella linearis profunda are reported for the first time since their original descriptions. Anguinella palmata was never reported before in Iberian waters, including both Atlantic and Mediterranean coasts. The record of Celleporella angusta extends the species' known southern limit of distribution. Another 12 species were previously reported only once in Portugal, sometimes with some doubts. In addition, the ovicell of Crepis longipes and the ancestrula of Herentia thalassae are here described for the first time. The presence in Smittina affinis of a denticulate distal border in the primary orifice and a well- developed peristome are reported. Two species of the genera Hincksina and Hemicyclopora, left in open nomenclature, are described.
The adverse effects of cryptochirid crabs (Decapoda: Brachyura) on Siderastrea stellata Verril, 1868 (Anthozoa: Scleractinia): causes and consequences of cavity establishment
Creators: name: NOGUEIRA, Marcos M.
name: MENEZES, Natalia M.
name: JOHNSSON, Rodrigo
name: NEVES, Elizabeth
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2014

description: In marine environments, a wide range of small, cryptic invertebrates are specialist inhabitants of sessile Scleractinian corals, the exclusive hosts of cryptochirid crabs which reside in the cavities of infested coral colonies. These cavities likely affect coral growth, especially when crabs colonize the surface of the corals early in their development. The spatial distribution of cryptochirids on hosts has not yet been fully assessed, but this information has important implications for competitive interactions between crabs. This study aims to analyse the structure and spatial distribution of the Brazilian gall crab Kroppcarcinus siderastreicola on Siderastrea stellata. Crabs inhabited 21% of the colonies that were sampled. The relationship between coral size and cavity size was determined by using Spearman's correlation. The results confirm the assumption that crabs negatively influence coral growth rates. In addition, the relationship between the mean distance between cavities and coral size indicates that the establishment of new crabs may be affected by the occupation of previous crabs.
(3815) John Currie Smith
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
SUR LE DÉVELOPPEMENT POST-LARVAIRE D'HIPPOPODIUS HIPPOPUS (FORSKAL)
Creators: name: CARRÉ, Danièle
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1968

description: Various post larval stages of Hippopodius hippopus are described from specimens collected in the plancton. The general morphology of the latter are in agreement with that already described for Hippopodius larval but some important features had not been specified which has led to errors of determination and mistakes. The larval nectophore has only two radial canal and the first definitive nectophore has only two knobs which differentiates itself from the following definitive nectophores granted with fours knobs.
Data management plan & handbook Version 1.0
Creators: name: Kieslinger, Barbara
name: Schäfer, Teresa
name: Fabian, Claudia M.
Publisher: name: Zenodo
Year: 2018

description: This Project Handbook describes the internal procedures of the Made4You consortium in terms
 of management structures, communication and collaboration as well as quality control
 measures. It also defines the way the partners are dealing with Responsible Research and
 Innovation (RRI), especially considering ethical issues related to personal data collection,
 analysis and storage (see also Deliverable D8.1. and D8.2 on ethics requirements). Open source
 and open access are important elements of RRI and the strategy of the consortium in dealing
 with these aspects is reflected in the open data management plan, which forms part of this
 document.
 The main target group for this deliverable are the consortium partners themselves as this
 handbook defines the project internal processes for securing high quality research work to be
 performed across a set of complementary partner institutions. It serves as a reference document
 for all Made4You team members including individuals joining in the project at a later stage.
LA RÉGÉNÉRATION ET L'EMBRYOGENÈSE SOMATIQUE DE CERTAINS TURBELLARIÉS
Creators: name: ISAEVA, V.V.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1968

description: The author investigated the capacity for regeneration and somatic embryogenesis (i.e. the development of the whole organism from isolated small part of the body) of the turbellaria : Convoluta convoluta, Mecynostomum sp., Haploposthia opisthorhis (Acoela), Dugesia tigrina, Dendrocoelum lacteum (Triclada). Among these species only Dugesia tigrina reproduces asexually. The relation of regeneration phenomena with the presence or absence of asexual reproduction was found. The regeneration proper is more characteristic for the species which are reproducing sexually only, while in Dugesia tigrina it is easy to provoke the somatic embryogenesis.
The appearence in Dugesia tigrina of various anomalies (outgrowths - “tumours”, additional heads, tails, pharynxes and inversions of normal polarity) after treatment by benzpyren and other injurious influences are considered as phenomena similar to somatic embryogenesis. The injurious factors used have, in general, a nonspecific effect, provoking a disturbance of normal integration of organism.
In the course of ontogenesis, the decrease of capacity for regeneration proper is observed (regeneration of young vermes goes on more rapidly than that of theolderones).At the same time in adult individuals of Dugesia tigrina, which have asexual reproduction more often, the author observed the higher rate of the process of somatic embryogenesis as compared to young animals.
The data confirm the idea of relationship between phenomena of regeneration, somatic embryogenesis and the level of integration of organism and the presence or absence of asexual propagation.
A Compositional Framework for Markov Processes
Creators: name: Baez, John C.
name: Fong, Brendan
name: Pollard, Blake S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Physics (math-ph)
subject: Category Theory (math.CT)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We define the concept of an "open" Markov process, or more precisely, continuous-time Markov chain, which is one where probability can flow in or out of certain states called "inputs" and "outputs". One can build up a Markov process from smaller open pieces. This process is formalized by making open Markov processes into the morphisms of a dagger compact category. We show that the behavior of a detailed balanced open Markov process is determined by a principle of minimum dissipation, closely related to Prigogine's principle of minimum entropy production. Using this fact, we set up a functor mapping open detailed balanced Markov processes to open circuits made of linear resistors. We also describe how to "black box" an open Markov process, obtaining the linear relation between input and output data that holds in any steady state, including nonequilibrium steady states with a nonzero flow of probability through the system. We prove that black boxing gives a symmetric monoidal dagger functor sending open detailed balanced Markov processes to Lagrangian relations between symplectic vector spaces. This allows us to compute the steady state behavior of an open detailed balanced Markov process from the behaviors of smaller pieces from which it is built. We relate this black box functor to a previously constructed black box functor for circuits.
description: 43 pages, TikZ figures
The use of otolith chemistry to determine stock structure of Sardina pilchardus and Engraulis encrasicolus in Tunisian Coasts
Creators: name: KHEMIRI, Sana
name: LABONNE, Maylis
name: GAAMOUR, Adel
name: MUNARON, Jean-Marie
name: MORIZE, Eric
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2014

description: Sardina pilchardus and Engraulis encrasicolus are of great economic importance in Tunisia. However, little is known about their stock structure. Otolith chemistry was used to assess the feasibility of using this natural tag to discriminate populations of sardine and anchovy in the open sea and the coastal area of the Gulf of Gabes. The chemical composition of whole otoliths was analyzed using solution-based inductively coupled plasma mass spectrometry (ICPMS). Linear discriminant analysis classified fish into open sea and inshore groups with close to 97% accuracy for the anchovy and to 94% for the sardine. Respectively, the discrimination was based on P, Fe, Zn, Sc and Sr for the anchovy and P, Sr and B for the sardine. In addition, when we pool together the two species data in each area (inshore/open sea), the discrimination was also accurate reaching 88% of well classification based on P, Fe, Li and Mg. The results reveal a clear discreteness of the open sea and inshore small pelagic groups. Such information will have major implications for fisheries management of sardine and anchovy in Tunisia.
Muscle ring finger protein-1 inhibits PKCε activation and prevents cardiomyocyte hypertrophy
Creators: name: McDonough, Holly
name: Kedar, Vishram
name: Hwang, Jae Ryoung
name: Patterson, Cam
name: Li, Hui Hua
name: Taylor, Joan
name: Arya, Ranjana
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Much effort has focused on characterizing the signal transduction cascades that are associated with cardiac hypertrophy. In spite of this, we still know little about the mechanisms that inhibit hypertrophic growth. We define a novel anti-hypertrophic signaling pathway regulated by muscle ring finger protein-1 (MURF1) that inhibits the agonist-stimulated PKC-mediated signaling response in neonatal rat ventricular myocytes. MURF1 interacts with receptor for activated protein kinase C (RACK1) and colocalizes with RACK1 after activation with phenylephrine or PMA. Coincident with this agonist-stimulated interaction, MURF1 blocks PKCε translocation to focal adhesions, which is a critical event in the hypertrophic signaling cascade. MURF1 inhibits focal adhesion formation, and the activity of downstream effector ERK1/2 is also inhibited in the presence of MURF1. MURF1 inhibits phenylephrine-induced (but not IGF-1–induced) increases in cell size. These findings establish that MURF1 is a key regulator of the PKC-dependent hypertrophic response and can blunt cardiomyocyte hypertrophy, which may have important implications in the pathophysiology of clinical cardiac hypertrophy.
Orbital Magnetization in Insulators: Bulk vs. Surface
Creators: name: Bianco, Raffaello
name: Resta, Raffaele
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The orbital magnetic moment of a finite piece of matter is expressed in terms of the one-body density matrix as a simple trace. We address a macroscopic system, insulating in the bulk, and we show that its orbital moment is the sum of a bulk term and a surface term, both extensive. The latter only occurs when the transverse conductivity is nonzero and owes to conducting surface states. Simulations on a model Hamiltonian validate our theory.
A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes membrane growth of Arabidopsis thaliana root hairs
Creators: name: Fairbrother, Ashley
name: Mekeel, Hal
name: Bankaitis, Vytas A.
name: Vincent, Patrick
name: Bibikova, Tatiana N.
name: Nogue, Fabien
name: Gilroy, Simon
name: Xu, Yue
name: Allen, Nina
name: Chua, Michael
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Phosphatidylinositol (PtdIns) transfer proteins (PITPs) regulate signaling interfaces between lipid metabolism and membrane trafficking. Herein, we demonstrate that AtSfh1p, a member of a large and uncharacterized Arabidopsis thaliana Sec14p-nodulin domain family, is a PITP that regulates a specific stage in root hair development. AtSfh1p localizes along the root hair plasma membrane and is enriched in discrete plasma membrane domains and in the root hair tip cytoplasm. This localization pattern recapitulates that visualized for PtdIns(4,5)P2 in developing root hairs. Gene ablation experiments show AtSfh1p nullizygosity compromises polarized root hair expansion in a manner that coincides with loss of tip-directed PtdIns(4,5)P2, dispersal of secretory vesicles from the tip cytoplasm, loss of the tip f-actin network, and manifest disorganization of the root hair microtubule cytoskeleton. Derangement of tip-directed Ca2+ gradients is also apparent and results from isotropic influx of Ca2+ from the extracellular milieu. We propose AtSfh1p regulates intracellular and plasma membrane phosphoinositide polarity landmarks that focus membrane trafficking, Ca2+ signaling, and cytoskeleton functions to the growing root hair apex. We further suggest that Sec14p-nodulin domain proteins represent a family of regulators of polarized membrane growth in plants.
Haematological and biochemical response of Mugil cephalus after acclimation to captivity
Creators: name: FAGGIO, Caterina
name: FEDELE, Grazia
name: ARFUSO, Francesca
name: PANZERA, Michele
name: FAZIO, Francesco
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2014

description: In this study the effect of acclimation to captivity on haematological and biochemical parameters of Mugil cephalus was investigated. A total of fifteen fish (21.93 ± 2.03 cm fork length; 80.28 ± 21.32 g weight) was harvested from a Reservoir-Faro Lake, Messina (Italy). Immediately after capture blood samples was collected on all fish to evaluate haematological parameters, glucose and lactate levels. Then, all animals were transferred in tank and acclimated for a period of 15 days. After this acclimate period, on all fish blood samples were collected and the blood parameter were assessed again. Paired t-test, used to determine significant differences between blood parameters measured before and after acclimation, showed that after acclimation to captivity, there was significant reduction (P < 0.001) in red blood cell (RBC), Haematocrit (Hct), Haemoglobin concentration (Hgb), White Blood Cell Count (WBC). Lactate and total proteins values increased significantly after acclimation (P < 0.001 and P < 0.05, respectively), while glucose blood concentration decreased significantly (P < 0.001). The results of this study showed how haematological and biochemical parameters of the mullet change after acclimation to captivity.
Transitions in the Stock Markets of the US, UK, and Germany
Creators: name: Raddant, Matthias
name: Wagner, Friedrich
Publisher: name: arXiv
Year: 2015
Subjects: subject: Portfolio Management (q-fin.PM)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: General Economics (econ.GN)
subject: FOS: Economics and business
subject: FOS: Physical sciences

description: In an analysis of the US, the UK, and the German stock market we find a change in the behavior based on the stock's beta values. Before 2006 risky trades were concentrated on stocks in the IT and technology sector. Afterwards risky trading takes place for stocks from the financial sector. We show that an agent-based model can reproduce these changes. We further show that the initial impulse for the transition might stem from the increase of high frequency trading at that time.
Seasonal and depth-related biodiversity of leaf epiphytic Cheilostome Bryozoa in a Mediterranean Posidonia oceanica meadow
Creators: name: LEPOINT, Gilles
name: BALANCIER, Boris
name: GOBERT, Sylvie
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2014

description: Epiphytes living fixed on Posidonia oceanica L. (Delile) are important faunal and floral components of seagrass meadow ecosystems. They are involved as main actors in trophic web and major ecosystem processes of this endangered coastal habitat. This paper aims to assess the seasonality and the bathymetric variability of epiphytic Bryozoa which are the most important animal group in terms of both diversity and abundance living on P. oceanica leaves. Posidonia shoots were collected from the Revellata Bay (Corsica, France) in four seasons from 7 to 30 m depth. Colony densities reached more than 87000 colonies.m-2 at 10 m depth in spring. The bryozoan species distribution and abundance changed substantially according to seasons and depths, being maximum in spring and minimal in winter. Dominant colony morphotypes change according to depth, probably in relation with water motion gradient. This confirms that there are bathymetric and seasonal variability for different epiphytic organisms colonizing the Posidonia leaves. This enlightens the importance to protect Posidonia meadow on its full depth extension and in its connectivity with other habitats to conserve optimal epiphytic biodiversity and functions.
Epigenetic manipulation of gene expression: a toolkit for cell biologists
Creators: name: Kim, Tai Young
name: Juliano, Rudy L.
name: Miyamoto, Yuko
name: Kang, Hyunmin
name: Xu, Dong
name: Dixit, Vidula R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Cell biologists have been afforded extraordinary new opportunities for experimentation by the emergence of powerful technologies that allow the selective manipulation of gene expression. Currently, RNA interference is very much in the limelight; however, significant progress has also been made with two other approaches. Thus, antisense oligonucleotide technology is undergoing a resurgence as a result of improvements in the chemistry of these molecules, whereas designed transcription factors offer a powerful and increasingly convenient strategy for either up- or down-regulation of targeted genes. This mini-review will highlight some of the key features of these three approaches to gene regulation, as well as provide pragmatic guidance concerning their use in cell biological experimentation based on our direct experience with each of these technologies. The approaches discussed here are being intensely pursued in terms of possible therapeutic applications. However, we will restrict our comments primarily to the cell culture situation, only briefly alluding to fundamental differences between utilization in animals versus cells.
Careables Legal and ethical inventory and in-depth analysis
Creators: name: Kamenjasevic, Erik
name: Biasin, Elisabetta
Publisher: name: Zenodo
Year: 2018

description: Careables.org has a goal of becoming an online platform that will serve as a central hub for
 sharing knowledge for reproduction and self-creation of customized healthcare solutions. It
 will encompass repository for the storage of projects’ technical documentation and it shall
 represent an environment where individuals with particular needs, healthcare professionals,
 makers, designers, donors and co-founders work collaboratively online in order to create cus-
 tom-made healthcare solutions – careables 1 . In order to develop a platform that respects all
 the applicable legal and ethical requirements, this deliverable is focusing on the following
 topics: privacy and data protection, intellectual property legal framework, liability and medi-
 cal devices, and ethics.
Experimental violation of a Bell-like inequality with optical vortex beams
Creators: name: Stoklasa, B.
name: Motka, L.
name: Rehacek, J.
name: Hradil, Z.
name: Sanchez-Soto, L. L.
name: Agarwal, G. S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Optical beams with topological singularities have a Schmidt decomposition. Hence, they display features typically associated with bipartite quantum systems; in particular, these classical beams can exhibit entanglement. This classical entanglement can be quantified by a Bell inequality formulated in terms of Wigner functions. We experimentally demonstrate the violation of this inequality for Laguerre-Gauss (LG) beams and confirm that the violation increases with increasing orbital angular momentum. Our measurements yield negativity of the Wigner function at the origin for $\LG_{10}$ beams, whereas for $\LG_{20}$ we always get a positive value.
description: 6 pages, 4 eps-color figures. Comments welcome!
Ontogenetic and temporal fluctuations in feeding habits of the Chilean croaker Cilus gilberti (Perciformes, Sciaenidae) in southern Chile
Creators: name: OYARZÚN, Ciro
name: FERNÁNDEZ, Camila
name: LANDAETA, Mauricio
name: CORTÉS, Nelson
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2001

description: The natural diet of Cilus gilberti was investigated from samples collected between December 1997 and November
 1998 in Southern Chile. This study showed the possible influence that seasonal changes and ontogenetic development of
 individuals may have on their feeding habits. The information was obtained by stomach contents analysis of 764 specimens
 caught by small scale fishery and comprising the whole legal capture size spectrum. Twenty six prey items (grouped in five
 major taxa) were found. Five month groups (Trophic Seasons, TS) were also identified. According to the quantitative
 analysis, C. gilberti behaves as an euryphagic, carnivorous species, feeding mainly on small fish (Engraulis ringens and
 Strangomera bentincki). During certain periods of the year, environmental changes can provoke a shift in prey importance
 toward small crustaceans (Neotrypaea uncinata) which increase dramatically in abundance during winter. The structure of
 the population adapts to changes in the environmental offer and maintains the ontogenetic organization, which includes a
 Ontogenetic Trophic Unit of middle sized fish (61-75 cm TL), that remains constant during most of the year, except during
 summer (december-january) and winter (june-july) periods.
Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis
Creators: name: Zhang, Jian
name: TerBush, Daniel
name: Wang, Puyue
name: Brennwald, Patrick
name: Gangar, Akanksha
name: Guo, Wei
name: Zhang, Xiaoyu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: The tumor suppressor lethal giant larvae (Lgl) plays a critical role in epithelial cell polarization. However, the molecular mechanism by which Lgl carries out its functions is unclear. In this study, we report that the yeast Lgl proteins Sro7p and Sro77p directly interact with Exo84p, which is a component of the exocyst complex that is essential for targeting vesicles to specific sites of the plasma membrane for exocytosis, and that this interaction is important for post-Golgi secretion. Genetic analyses demonstrate a molecular pathway from Rab and Rho GTPases through the exocyst and Lgl to SNAREs, which mediate membrane fusion. We also found that overexpression of Lgl and t-SNARE proteins not only improves exocytosis but also rescues polarity defects in exocyst mutants. We propose that, although Lgl is broadly distributed in the cells, its localized interaction with the exocyst and kinetic activation are important for the establishment and reenforcement of cell polarity.
CROISSANCE ET LONGÉVITÉ DE PATELLA VULGATA L. (GASTÉROPODE PROSOBRANCHE)
Creators: name: CHOQUET, Marcel
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1968

description: Our researches about the growth and longevity of Patella vulgata L. along the shore of the Boulogne area have been carried out by the means of stamps: the animals are periodically recaptured, measured and put back on the ground.
After considering the total growth of the population during several annual cycles, we have studied its variations with the seasons. The growth is discontinuous but is not subjected to winter pause except for a few older animals. It also differs according to the surroundings : it is more important on limpets living under Fucus than on those inhabiting rocks covered with barnacles. The rate of growth decreases directly with age.
The rythm of linear growth is the result of several influences, the most important of which seem to be the temperature, the nutrition and the sexual life. The successive stages of the limpets’s life are recorded from the hatching time in the course of the same annual generation and considering the variation of the sex-ratio depending on the length and the seasons (Choquet 1966). The possible longevity is five or six years; this fact is compared with those found for some Patellacea.
OCEAN TEMPERATURE AND SALINITY OFF ROSCOFF FROM 1971 TO 1982 - STUDY OF THE TENDENCY BETWEEN 1961 AND 1982 (SOUTH OF THE WEST CHANNEL)
Creators: name: Latrouite, D.
name: Raguenes, G.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1985

Abstract
(3817) Ian Gordon Munro
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Atrial Myopathy: Analysing the link to ischaemic stroke.
Creators: name: JITHIN KOSHY SAJEEV
Publisher: name: Monash University
Year: 2020
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine
subject: Neuroscience

description: In Australia approximately 60,000 strokes occur every year of which 30% do not have a recognised cause. A significant proportion of these strokes are thought to originate in the heart as a result of clot formation that ultimately migrates to the brain resulting in a stroke. This thesis aims to summarise the current mechanism for stroke. We used various modalities of investigations to identify markers of abnormal heart structure and function that occur in patients with stroke. In the future, these markers may allow us to identify patients at risk for stroke and lead to novel treatment strategies.
Dynamics of multi-stable states during ongoing and evoked cortical activity
Creators: name: Mazzucato, Luca
name: Fontanini, Alfredo
name: La Camera, Giancarlo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: Single trial analyses of ensemble activity in alert animals demonstrate that cortical circuits dynamics evolve through temporal sequences of metastable states. Metastability has been studied for its potential role in sensory coding, memory and decision-making. Yet, very little is known about the network mechanisms responsible for its genesis. It is often assumed that the onset of state sequences is triggered by an external stimulus. Here we show that state sequences can be observed also in the absence of overt sensory stimulation. Analysis of multielectrode recordings from the gustatory cortex of alert rats revealed ongoing sequences of states, where single neurons spontaneously attain several firing rates across different states. This single neuron multi-stability represents a challenge to existing spiking network models, where typically each neuron is at most bi-stable. We present a recurrent spiking network model that accounts for both the spontaneous generation of state sequences and the multi-stability in single neuron firing rates. Each state results from the activation of neural clusters with potentiated intra-cluster connections, with the firing rate in each cluster depending on the number of active clusters. Simulations show that the models ensemble activity hops among the different states, reproducing the ongoing dynamics observed in the data. When probed with external stimuli, the model predicts the quenching of single neuron multi-stability into bi-stability and the reduction of trial-by-trial variability. Both predictions were confirmed in the data. Altogether, these results provide a theoretical framework that captures both ongoing and evoked network dynamics in a single mechanistic model.
description: 34 pages, 11 figures; v2: typos in Methods section corrected; v3: typos corrected
Trapping of classical particles by an electromagnetic radiation amplifying with time
Creators: name: Izmailov, Azad Ch.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Physics (physics.gen-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We analyze new possible applications of the trapping mechanism of sufficiently slow-speed particles by an electromagnetic potential well deepening with time (up to a certain limit) which was recently established by author from basic relations of classical mechanics. It is assumed that given particles are under conditions of the high vacuum and forces acting on these particles are not dissipative. Such wells may be created by means of an electromagnetic field (in particular radiation) with a fixed spatial distribution but with a nondecreasing strength in time. Trapping and localization of particles in such electromagnetic traps are analyzed on example of typical laser beams. Obtained results may be used in high resolution spectroscopy of various particles (including also atoms and molecules in definite cases).
description: 8 pages, 3 figures
Diversity and vertical distribution of nematode assemblages the Saguenay fjord (Quebec, Canada) environmental
Creators: name: TITA, Guglielmo
name: DESROSIERS, Gaston
name: VINCX, Magda
name: GAGNÉ, Jean-Pierre
name: LOCAT, Jacques
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2001

description: Three stations were sampled for a meiofaunal survey in the Saguenay fjord's inner basin (Quebec, Canada).
 Nematodes were the dominant taxon accounting for 90 % of total individuals. Twenty nematode families and 55 genera were
 found. Cluster analysis showed two different depth-segregated nematode assemblages, one in the surface layer (0-2 cm) and
 the other in the subsurface layer (2-10 cm) of the sediment column. A comparison between abundance and biomass vertical
 distributions showed that smaller individuals were dominant in the surface sediment layer, while larger individuals
 dominated in subsurface sediment. Selective deposit-feeders were the most abundant feeding group, while epigrowth-feeders
 were dominant in terms of biomass. Diversity tended to decrease in downstream areas of the fjord. Species composition and
 size spectra at the three stations suggest the succession of different meiofaunal communities along the fjord. Abundance-
 biomass comparison (ABC) plots suggested that upstream areas were moderately disturbed. The difference between
 Shannon's index in terms of abundance and biomass (H'δ = H'abund - H'biom) is suggested to be a useful tool in detecting
 environmental disturbance.
Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex
Creators: name: Brennwald, Patrick
name: Bloom, Kerry
name: Roumanie, Olivier
name: Rossi, Guendalina
name: Molk, Jeffrey N.
name: Wu, Hao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Rho GTPases are important regulators of polarity in eukaryotic cells. In yeast they are involved in regulating the docking and fusion of secretory vesicles with the cell surface. Our analysis of a Rho3 mutant that is unable to interact with the Exo70 subunit of the exocyst reveals a normal polarization of the exocyst complex as well as other polarity markers. We also find that there is no redundancy between the Rho3–Exo70 and Rho1–Sec3 pathways in the localization of the exocyst. This suggests that Rho3 and Cdc42 act to polarize exocytosis by activating the exocytic machinery at the membrane without the need to first recruit it to sites of polarized growth. Consistent with this model, we find that the ability of Rho3 and Cdc42 to hydrolyze GTP is not required for their role in secretion. Moreover, our analysis of the Sec3 subunit of the exocyst suggests that polarization of the exocyst may be a consequence rather than a cause of polarized exocytosis.
High-precision calculation of the strange nucleon electromagnetic form factors
Creators: name: Green, Jeremy
name: Meinel, Stefan
name: Engelhardt, Michael
name: Krieg, Stefan
name: Laeuchli, Jesse
name: Negele, John
name: Orginos, Kostas
name: Pochinsky, Andrew
name: Syritsyn, Sergey
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We report a direct lattice QCD calculation of the strange nucleon electromagnetic form factors $G_E^s$ and $G_M^s$ in the kinematic range $0 \leq Q^2 \lesssim 1.2\: {\rm GeV}^2$. For the first time, both $G_E^s$ and $G_M^s$ are shown to be nonzero with high significance. This work uses closer-to-physical lattice parameters than previous calculations, and achieves an unprecedented statistical precision by implementing a recently proposed variance reduction technique called hierarchical probing. We perform model-independent fits of the form factor shapes using the $z$-expansion and determine the strange electric and magnetic radii and magnetic moment. We compare our results to parity-violating electron-proton scattering data and to other theoretical studies.
description: 6 pages, 5 figures. v2: references added
Interim Activity & Management Report (Periodic Technical Report - Part B)
Creators: name: Kieslinger, Barbara
name: Fabian, Claudia M.
Publisher: name: Zenodo
Year: 2020

description: This is the mid-term progress report including month 1 till month 18 of the
 Made4You project. It gives an overview of the work carried out and the projects
 results achieved during the reporting period.
(3812) Ramsey D Duff
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A note on absorption semigroups and regularity
Creators: name: Manavi, Amir
name: Vogt, Hendrik
name: Voigt, Jürgen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 47D06, 47A55, 47B60

description: It is shown that, in the theory of absorption semigroups, two possible ways of defining regularity for absorption rates are in fact equivalent.
Laubierpholoe indooceanica, a new interstitial polychaete (Pholoidae) from South India and the Seychelles
Creators: name: WESTHEIDE, Wilfried
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2001

description: An interstitial pholoid, Laubierpholoe indooceanica, new species, is described from sand sediments of coral reef
 flats of the Indian island Krusadai and the Seychelles island Mahé. As in the other four species of the genus, embryos develop
 in brood pouches in each of two elytra. Features of chaetation, especially the presence of hook-like blades in some of the
 compound neurochaetae, are the distinguishing characters of the species.
MISO high penetration renewable energy study for 2050
Creators: name: Clack, Christopher T
Publisher: name: figshare
Year: 2020
Subjects: subject: 91305 Energy Generation, Conversion and Storage Engineering
subject: FOS: Mechanical engineering
subject: 90608 Renewable Power and Energy Systems Engineering (excl. Solar Cells)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: Atmospheric Sciences
subject: FOS: Earth and related environmental sciences
subject: Economics

description: Reducing emissions across the MISO footprint using co-optimization theory.
The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila
Creators: name: Harris, Tony J.C.
name: Peifer, Mark
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Cell polarity is critical for epithelial structure and function. Adherens junctions (AJs) often direct this polarity, but we previously found that Bazooka (Baz) acts upstream of AJs as epithelial polarity is first established in Drosophila . This prompted us to ask how Baz is positioned and how downstream polarity is elaborated. Surprisingly, we found that Baz localizes to an apical domain below its typical binding partners atypical protein kinase C (aPKC) and partitioning defective (PAR)-6 as the Drosophila epithelium first forms. In fact, Baz positioning is independent of aPKC and PAR-6 relying instead on cytoskeletal cues, including an apical scaffold and dynein-mediated basal-to-apical transport. AJ assembly is closely coupled to Baz positioning, whereas aPKC and PAR-6 are positioned separately. This forms a stratified apical domain with Baz and AJs localizing basal to aPKC and PAR-6, and we identify specific mechanisms that keep these proteins apart. These results reveal key steps in the assembly of the apical domain in Drosophila .
CIB1 is an endogenous inhibitor of agonist-induced integrin αIIbβ3 activation
Creators: name: Boudignon-Proudhon, Christel
name: Parise, Leslie V.
name: Lam, Stephen C.T.
name: Wang, Zhengyan
name: Clark, Shantres
name: Yuan, Weiping
name: Larson, Mark K.
name: McFadden, Andrew W.
name: Leisner, Tina M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: In response to agonist stimulation, the αIIbβ3 integrin on platelets is converted to an active conformation that binds fibrinogen and mediates platelet aggregation. This process contributes to both normal hemostasis and thrombosis. Activation of αIIbβ3 is believed to occur in part via engagement of the β3 cytoplasmic tail with talin; however, the role of the αIIb tail and its potential binding partners in regulating αIIbβ3 activation is less clear. We report that calcium and integrin binding protein 1 (CIB1), which interacts directly with the αIIb tail, is an endogenous inhibitor of αIIbβ3 activation; overexpression of CIB1 in megakaryocytes blocks agonist-induced αIIbβ3 activation, whereas reduction of endogenous CIB1 via RNA interference enhances activation. CIB1 appears to inhibit integrin activation by competing with talin for binding to αIIbβ3, thus providing a model for tightly controlled regulation of αIIbβ3 activation.
Direct measurement of the lamellipodial protrusive force in a migrating cell
Creators: name: Mogilner, Alex
name: Prass, Marcus
name: Jacobson, Ken
name: Radmacher, Manfred
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: There has been a great deal of interest in the mechanism of lamellipodial protrusion (Pollard, T., and G. Borisy. 2003. Cell. 112:453–465). However, one of this mechanism's endpoints, the force of protrusion, has never been directly measured. We place an atomic force microscopy cantilever in the path of a migrating keratocyte. The deflection of the cantilever, which occurs over a period of ∼10 s, provides a direct measure of the force exerted by the lamellipodial leading edge. Stall forces are consistent with ∼100 polymerizing actin filaments per micrometer of the leading edge, each working as an elastic Brownian ratchet and generating a force of several piconewtons. However, the force-velocity curves obtained from this measurement, in which velocity drops sharply under very small loads, is not sensitive to low loading forces, and finally stalls rapidly at large loads, are not consistent with current theoretical models for the actin polymerization force. Rather, the curves indicate that the protrusive force generation is a complex multiphase process involving actin and adhesion dynamics.
(3814) Alice Muriel Barbara Smith
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.