cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?
Creators: name: Beekes, Michael
name: Thomzig, Achim
name: Schulz-Schaeffer, Walter J.
name: Burger, Reinhard
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2014
Subjects: subject: Alzheimer’s disease
subject: Parkinson’s disease
subject: Prion
subject: Prion protein
subject: Seed
subject: Amyloid-β (Aβ)
subject: Tau
subject: α-Synuclein
subject: Transmission
subject: Risk
subject: 610 Medizin

description: The misfolding and aggregation of endogenous proteins in the central nervous system is a neuropathological hallmark of Alzheimer’s disease (AD), Parkinson’s disease (PD), as well as prion diseases. A molecular mechanism referred to as “nucleation-dependent aggregation” is thought to underlie this neuropathological phenomenon. According to this concept, disease-associated protein particles act as nuclei, or seeds, that recruit cellular proteins and incorporate them, in a misfolded form, into their growing aggregate structure. Experimental studies have shown that the aggregation of the AD-associated proteins amyloid-β (Aβ) and tau, and of the PD-associated protein α-synuclein, can be stimulated in laboratory animal models by intracerebral (i.c.) injection of inocula containing aggregated species of the respective proteins. This has raised the question of whether AD or PD can be transmitted, like certain human prion diseases, between individuals by self-propagating protein particles potentially present on medical instruments or in blood or blood products. While the i.c. injection of inocula containing AD- or PD-associated protein aggregates was found to cause neuronal damage and clinical abnormalities (e.g., motor impairments) in some animal models, none of the studies published so far provided evidence for a transmission of severe or even fatal disease. In addition, available epidemiological data do not indicate a transmissibility of AD or PD between humans. The findings published so far on the effects of experimentally transmitted AD- or PD-associated protein seeds do not suggest specific precautionary measures in the context of hemotherapy, but call for vigilance in transfusion medicine and other medical areas.
Noch nie dagewesen? Hochwasser und Starkregen im Juli 2021 und im Juli 1342
Creators: name: Schreg, Rainer
Publisher: name: Humanities Commons
Year: 2021
Subjects: subject: Archaeology, Medieval
subject: Environmental conditions
subject: Environmental archaeology

description: This blogpost compares the flood events from 2021 and 1342. The example of St. Magdalein's flood in 1342 challenges modern risk assessment and contributes to the environmental history of times of climate change. The blogpost presents a short review of the state of research especially in the landscapes along the river Main.
Noch nie dagewesen? Hochwasser und Starkregen im Juli 2021 und im Juli 1342
Creators: name: Schreg, Rainer
Publisher: name: unknown
Year: 2021
Subjects: subject: Environmental archaeology
subject: Environmental conditions
subject: Archaeology, Medieval

description: This blogpost compares the flood events from 2021 and 1342. The example of St. Magdalein's flood in 1342 challenges modern risk assessment and contributes to the environmental history of times of climate change. The blogpost presents a short review of the state of research especially in the landscapes along the river Main.
Impact of Acinetobacter baumannii Superoxide Dismutase on Motility, Virulence, Oxidative Stress Resistance and Susceptibility to Antibiotics
Creators: name: Heindorf, Magdalena
name: Kadari, Mahendar
name: Heider, Christine
name: Skiebe, Evelyn
name: Wilharm, Gottfried
Publisher: name: Robert Koch-Institut
Year: 2014
Subjects: subject: Animals
subject: Mutation
subject: Acinetobacter baumannii/metabolism
subject: Acinetobacter baumannii/pathogenicity
subject: Anti-Bacterial Agents/pharmacology
subject: Drug Resistance Bacterial
subject: Acinetobacter baumannii/drug effects
subject: Acinetobacter baumannii/enzymology
subject: Enzyme Activation/drug effects
subject: Lepidoptera/microbiology
subject: Movement/drug effects
subject: Oxidative Stress/drug effects
subject: Reactive Oxygen Species/metabolism
subject: Superoxide Dismutase/genetics
subject: Superoxide Dismutase/metabolism
subject: 610 Medizin

description: Acinetobacter baumannii is a Gram-negative bacterium appearing as an opportunistic pathogen in hospital settings. Superoxide dismutase (SOD) contributes to virulence in several pathogenic bacteria by detoxifying reactive oxygen species released in the course of host defense reactions. However, the biological role of SODs in A. baumannii has not yet been elucidated. Here, we inactivated in A. baumannii ATCC 17978 gene A1S_2343, encoding a putative SOD of the Fe-Mn type by transposon insertion, resulting in mutant ATCC 17978 sod2343::Km. The mutation was also introduced in two naturally competent A. baumannii isolates by transformation with chromosomal DNA derived from mutant ATCC 17978 sod2343::Km. We demonstrate that inactivation of sod2343 leads to significant motility defects in all three A. baumannii strains. The mutant strains were more susceptible to oxidative stress compared to their parental strains. Susceptibility to colistin and tetracycline was increased in all mutant strains while susceptibility of the mutants to gentamicin, levofloxacin and imipenem was strain-dependent. In the Galleria mellonella infection model the mutant strains were significantly attenuated. In conclusion, sod2343 plays an important role in motility, resistance to oxidative stress, susceptibility to antibiotics and virulence in A. baumannii.
Effekte der Masern-Mumps-Röteln (MMR)-Impfung auf die Epidemiologie von Mumps in Deutschland
Creators: name: Koch, Judith
name: Takla, Anja
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2013
Subjects: subject: Epidemiologie
subject: Deutschland
subject: Mumps
subject: Parotitis epidemica
subject: MMR-Impfung
subject: Germany
subject: Epidemiology
subject: Epidemic parotitis
subject: MMR vaccination
subject: 610 Medizin

description: Mumps ist eine akute virale Infektionskrankheit, die durch eine ein- bzw. beidseitige schmerzhafte Parotisschwellung gekennzeichnet ist. Seit 1976 empfiehlt die Ständige Impfkommission (STIKO) in der Bundesrepublik die Mumpsimpfung als Standardimpfung im Kindesalter. In den östlichen Bundesländern wurde die Impfung nach der Wiedervereinigung eingeführt. In Deutschland hat es während der letzten Jahrzehnte kein einheitliches Surveillancesystem zur Überwachung der Mumpsepidemiologie gegeben. Für die ehemalige DDR und die östlichen Bundesländer können Mumpserkrankungen auf der Basis von Daten aus verschiedenen Überwachungssystemen für den Zeitraum von 1968 bis 2012 abgebildet werden. Demnach ist die Mumpsinzidenz von jährlich > 200 Erkrankungen/100.000 Einwohner in der Vorimpfära auf mittlerweile weniger als  95 % gesteigert und bestehende Impflücken unter Erwachsenen geschlossen werden können.
description: Mumps is an acute viral infectious disease characterized by fever and swelling and tenderness of one or more salivary glands, usually the parotid gland. Since 1976, the German Standing Committee on Vaccination (STIKO) has recommended a mumps vaccination as part of the routine immunization schedule in former West Germany. In East Germany, the vaccination was only introduced in 1991 after reunification. In the preceding decades, no comprehensive surveillance system existed in Germany. However, for East Germany and the successional federal states of former East Germany, data on mumps incidence are available from different Eastern surveillance systems for the time period 1968–2012. According to these data, the incidence of mumps has dropped from > 200 cases/100,000 annually in the pre-vaccine era to currently
Spin-$S\,$ Kitaev-Heisenberg model on the honeycomb lattice: A high-order treatment via the many-body coupled cluster method
Creators: name: Georgiou, Marios
name: Rousochatzakis, Ioannis
name: Farnell, Damian J. J.
name: Richter, Johannes
name: Bishop, Raymond F.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the spin-$S$ Kitaev-Heisenberg model on the honeycomb lattice for $S\!=\!1/2$, $1$ and $3/2$, by using the coupled cluster method (CCM) of microscopic quantum many-body theory. This system is one of the earliest extensions of the Kitaev model and is believed to contain two extended spin liquid phases for any value of the spin quantum number $S$. We show that the CCM delivers accurate estimates for the phase boundaries of these spin liquid phases, as well as other transition points in the phase diagram. Moreover, we find evidence of two unexpected narrow phases for $S\!=\!1/2$, one sandwiched between the zigzag and ferromagnetic phases and the other between the Néel and the stripy phases. The results establish the CCM as a versatile numerical technique that can capture the strong quantum-mechanical fluctuations that are inherently present in generalized Kitaev models with competing bond-dependent anisotropies.
description: 16 pages, 10 figures. This version: figures 5,8 and 10 updated, Table I updated, references added
Measles virus spread initiated at international mass gatherings in Europe, 2011
Creators: name: Santibanez, Sabine
name: Prosenc, K.
name: Lohr, D.
name: Pfaff, Günter
name: Markocic, O. Jordan
name: Mankertz, Annette
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2014
Subjects: subject: Germany
subject: Humans
subject: Female
subject: Male
subject: Adolescent
subject: Adult
subject: Middle Aged
subject: Young Adult
subject: Genotype
subject: Phylogeny
subject: Age Distribution
subject: Child
subject: Measles/epidemiology
subject: Measles/transmission
subject: Measles virus/genetics
subject: Travel
subject: Sentinel Surveillance
subject: Crowding
subject: Disease Outbreaks/prevention & control
subject: Italy
subject: Measles/diagnosis
subject: Measles/virology
subject: Measles virus/classification
subject: Measles virus/isolation & purification
subject: Slovenia
subject: Soccer
subject: 610 Medizin

description: Three parallel transmission chains of measles virus (MV) variant ‘D8-Villupuram’ (D8-V) originated from two coinciding international mass gathering (MG) events in Rimini, Italy, in June 2011. MV D8-V was independently introduced into Germany by two unvaccinated persons, and into Slovenia by one unvaccinated person who had attended these events. Secondary spread of D8-V was restricted to two generations of transmission in Slovenia as well as in Germany where the virus was further disseminated at another MG. Serological and epidemiological investigation of the D8-V-associated German and Slovenian cases revealed different antibody responses and age distributions. Primary infected young persons between 11 and 27 years-old were affected in Germany, whereas the group of Slovenian cases comprised adults aged from 28 to 47 years and a high proportion (9/14; 64%) of patients with secondary vaccine failure (SVF). Our study demonstrates that monitoring of MV transmission chains in an international context and adequate serological investigation of cases with remote vaccination can contribute to identify susceptibility gaps.
Weighing protoplanetary discs with kinematics: physical model, method and benchmark
Creators: name: Veronesi, Benedetta
name: Longarini, Cristiano
name: Lodato, Giuseppe
name: Laibe, Guillaume
name: Hall, Cassandra
name: Facchini, Stefano
name: Testi, Leonardo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The mass of protoplanetary discs sets the amount of material available for planet formation, determines the level of coupling between gas and dust, and possibly sets gravitational instabilities. Measuring mass of discs is challenging, since it is not possible to directly detect H$_2$, and CO-based estimates remain poorly constrained. An alternative method that does not rely on tracers-to-H$_2$ ratios has recently been proposed to dynamically measure the disc mass altogether with the star mass and the disc critical radius by looking at deviations from Keplerian rotation induced by the self-gravity of the disc. So far, this method has been applied to weigh three protoplanetary discs: Elias 2-27, IM Lup and GM Aurigae. We provide here a numerical benchmark of the method by simulating isothermal self-gravitating discs with a range of masses from 0.01 to $0.2 \,M_{\odot}$ with the phantom code and post-process them with radiative transfer (mcfost) to obtain synthetic observations. We find that dynamical weighing allows to retrieve the expected value of disc masses as long as the disc-to-star mass ratio is larger than $M_d/M_\star=0.05$. The estimated uncertainty for the disc mass measurement is $\sim 25\%$.
description: 13 pages, 13 figures, accepted for publication on A&A
Foodborne hepatitis A outbreak associated with bakery products in northern Germany, 2012
Creators: name: Harries, Manuela
name: Monazahian, M.
name: Wenzel, J.
name: Jilg, Wolfgang
name: Weber, M.
name: Ehlers, J.
name: Dreesman, Johannes
name: Mertens, Elke
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2014
Subjects: subject: Humans
subject: Risk Assessment
subject: Male
subject: Adolescent
subject: Adult
subject: Aged
subject: Germany/epidemiology
subject: Middle Aged
subject: Risk Factors
subject: Young Adult
subject: Population Surveillance
subject: Base Sequence
subject: Interviews as Topic
subject: Child Preschool
subject: Child
subject: Disease Outbreaks
subject: Feces/virology
subject: Food Microbiology
subject: Reverse Transcriptase Polymerase Chain Reaction
subject: Case-Control Studies
subject: Multivariate Analysis
subject: Food Contamination/statistics & numerical data
subject: Hepatitis A/blood
subject: Hepatitis A/epidemiology
subject: Hepatitis A/transmission
subject: Hepatitis A/virology
subject: Hepatovirus/genetics
subject: Hepatovirus/isolation & purification
subject: Immunoenzyme Techniques
subject: 610 Medizin

description: In October 2012, a hepatitis A (HA) outbreak with 83 laboratory-confirmed cases occurred in Lower Saxony. We defined primary outbreak cases as people with laboratory-confirmed HA and symptom onset between 8 October and 12 November 2012, residing in or visiting the affected districts. Secondary outbreak cases were persons with symptom onset after 12 November 2012 and close contact with primary cases. We identified 77 primary and six secondary cases. We enrolled 50 primary cases and 52 controls matched for age and sex, and found that 82% of cases and 60% of controls had consumed products from a particular bakery (OR=3.09; 95% CI: 1.15–8.68). Cases were more likely to have eaten sweet pastries (OR=5.74; 95% CI: 1.46–22.42). Viral isolates from five selected cases and three positively tested surfaces in the bakery had identical nucleotide sequences. One additional identical isolate derived from a salesperson of the bakery suffering from a chronic disease that required immunosuppressive treatment. Epidemiological and laboratory findings suggested that the salesperson contaminated products while packing and selling. Future risk assessment should determine whether food handlers with chronic diseases under immunosuppressive treatment could be more at risk of contaminating food and might benefit from HAV immunisation.
Entanglement island and Page curve for one-sided charged black hole
Creators: name: Qu, Yun-Feng
name: Lan, Yi-Ling
name: Yu, Hongwei
name: Gan, Wen-Cong
name: Shu, Fu-Wen
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we extend the method of calculating the entanglement entropy of Hawking radiation of black holes using the "in" vacuum state, which describes one-sided asymptotically flat neutral black hole formed by gravitational collapse, to dynamic charged black holes. We explore the influence of charge on the position of the boundary of island $\partial I$ and the Page time. Due to their distinct geometric structures, we discuss non-extremal and extremal charged black holes separately. In non-extremal cases, the emergence of island saves the bound of entropy at late times, and the entanglement entropy of Hawking radiation satisfies the Page curve. Moreover, we also find that the position of the boundary of island $\partial I$ depends on the position of the cutoff surface (observers), differing from the behavior in eternal charged black holes. In extremal black holes, when the island exists, the entanglement entropy is approximately equal to the Bekenstein-Hawking entropy, while the entanglement entropy becomes ill-defined when island is absent. Our analysis underscores how different geometric configurations significantly influence the behavior of entropy.
The Yugoslav Nuclear Program in the Context of the Cold War
Creators: name: Korolija, Maja
Publisher: name: Humanities Commons
Year: 2024

description: Following the end of the Second World War, Yugoslavia embraced the Soviet ideological conception of society as the ideal model for all spheres of life, including science. In accordance with this, scientific work in the country should be planned, centralized and defined by the party-line. After the break-up with the USSR in 1948, especially at first, Yugoslavia showed a strong geopolitical inclination toward the Western Bloc. This led to the formation of a new state system of "Socialist Self-Management", but also brought about the rise of new discursive and organizational trends in Yugoslav science, which were compatible with certain elements of the perspective of science as autonomous – the hegemonic idea of science in the West.
Rotational synchronisation of B-type binaries in 30 Doradus
Creators: name: Lennon, D. J.
name: Dufton, P. L.
name: Villaseñor, J. I.
name: Langer, N.
name: Evans, C. J.
name: Sana, H.
name: Taylor, W. D.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The spin evolution of stars in close binary systems can be strongly affected by tides. We investigate the rotational synchronisation of the stellar components for 69 SB1 systems and 14 SB2 B-type systems in the 30 Doradus region of the Large Magellanic Cloud using observations from the VFTS and BBC surveys. Their orbital periods range from a few to a few hundred days, while estimated primary masses for these systems are in the range 5-20 Msun with mass ratio ranges of approximately q=0.03-0.5 and q=0.6-1.0 for the SB1 and SB2 systems, respectively. Projected rotational velocities of the stellar components have been compared with their synchronous velocities derived from the orbital periods. We find that effectively all systems with orbital period of more than 10 days must be asynchronous, whilst all the systems with periods of less than 3 days are likely synchronised. In terms of the stellar fractional radius (r), our results imply that all systems with r<0.1 are asynchronous, with those having r>0.2 probably being synchronised. For the apparently synchronised systems our results are more consistent with synchronisation at the mean orbital angular velocity rather than with that at periastron.
description: 13 pages, 5 figures. submitted to A&A
sj-docx-9-hpq-10.1177_13591053211027626 – for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK
Creators: name: Hanson, Kristin
name: O’Dwyer, Emma
name: Chaudhuri, Sharmistha
name: Silva Souza, Luiz Gustavo
name: Vandrevala, Tushna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: sj-docx-9-hpq-10.1177_13591053211027626 for Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK by Kristin Hanson, Emma O’Dwyer, Sharmistha Chaudhuri, Luiz Gustavo Silva Souza and Tushna Vandrevala in Journal of Health Psychology
"Alle Schreiben!" Eine Technik zur Erhöhung der Mitarbeit durch gründliches Nachdenken und zur wirksamen Vorbereitung von Klassendiskussionen
Creators: name: Bernhard, Roland
name: Köber, Kirsa
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Classroom management
subject: Effective teaching

description: The SQTE Classroom Management Snapshots were created as part of the "School Quality and Teacher Education" project (P31965 G), funded by the Austrian Science Fund (FWF). Their goal is to present evidence-based approaches to successful school quality development, as implemented in highly effective schools, and to prepare them for initial and continuing education, school development consulting, as well as for German-speaking educational practice, in a direct language. In this snapshot, we introduce a teaching strategy known as "everybody writes" in German language, which which helps to engage students cognitively in effective ways.
MHD simulations of the space weather in Proxima b: Habitability conditions and radio emission
Creators: name: Peña-Moñino, Luis
name: Pérez-Torres, Miguel
name: Varela, Jacobo
name: Zarka, Philippe
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The habitability of exoplanets hosted by M-dwarf stars dramatically depends on their space weather. We present 3D magneto-hydrodynamic simulations to characterise the magneto-plasma environment and thus the habitability of the Earth-like planet Proxima b when it is subject to both calm and extreme (CME-like) space weather conditions. We study the role of the stellar wind and planetary magnetic field, and determine the radio emission arising from the interaction between the stellar wind of Proxima and the magnetosphere of its planet Proxima b. We find that if Prox b has a magnetic field similar to that of the Earth ($B_{\rm p} = B_\oplus \approx 0.32$ G) or larger, the magnetopause standoff distance is large enough to shield the surface from the stellar wind for essentially any planetary tilt but the most extreme values (close to $90^{\circ} $), under a calm space weather. Even if Proxima b is subject to more extreme space weather conditions, the planet is well shielded by an Earth-like magnetosphere ($B_{\rm p} \approx B_\oplus$; $ \approx 23.5^{\circ}$), or if it has tilt smaller than that of the Earth. For calm space weather conditions, the radio emission caused by the day-side reconnection regions can be as high as 7$\times10^{19}$ erg s$^{-1}$ in the super-Alfvénic regime, and is on average almost an order of magnitude larger than the radio emission in the sub-Alfvénic cases, due to the much larger contribution of the bow shock. We also find that the energy dissipation at the bow shock is independent of the angle between the planet's magnetic dipole and the incident stellar wind flow. If Prox b is subject to extreme space weather conditions, the radio emission is more than two orders of magnitude larger than under calm space weather conditions. This result yields expectations for a direct detection--from Earth--in radio of giant planets in close-in orbits.
description: Accepted for publication in A&A (main journal). 14 pages, 8 figures. Videos showcasing the results of the simulation available at https://drive.google.com/drive/u/3/folders/10IJqLHo6DIn769BHb5vEzXxjObi5esL-
sj-pdf-1-jbx-10.1177_24725552211019409 – Supplemental material for Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening
Creators: name: Gradl, Stefan
name: Steuber, Holger
name: Weiske, Joerg
name: Szewczyk, Magda M.
name: Schmees, Norbert
name: Siegel, Stephan
name: Stoeckigt, Detlef
name: Christ, Clara D.
name: Li, Fengling
name: Organ, Shawna
name: Abbey, Megha
name: Kennedy, Steven
name: Chau, Irene
name: Trush, Viacheslav
name: Barsyte-Lovejoy, Dalia
name: Brown, Peter J.
name: Vedadi, Masoud
name: Arrowsmith, Cheryl
name: Husemann, Manfred
name: Badock, Volker
name: Bauser, Marcus
name: Haegebarth, Andrea
name: Hartung, Ingo V.
name: Stresemann, Carlo
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-jbx-10.1177_24725552211019409 for Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening by Stefan Gradl, Holger Steuber, Joerg Weiske, M. Szewczyk, Norbert Schmees, Stephan Siegel, Detlef Stoeckigt, Clara D. Christ, Fengling Li, Shawna Organ, Megha Abbey, Steven Kennedy, Irene Chau, Viacheslav Trush, Dalia Barsyte-Lovejoy, Peter J. Brown, Masoud Vedadi, Cheryl Arrowsmith, Manfred Husemann, Volker Badock, Marcus Bauser, Andrea Haegebarth, Ingo V. Hartung and Carlo Stresemann in SLAS Discovery
Additional file 1 of Impact of early preeclampsia prediction on medication adherence and behavior change: a survey of pregnant and recently-delivered individuals
Creators: name: Cowan, Alison
name: Haverty, Carrie
name: MacDonald, Reece
name: Khodursky, Arkady
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: Supplementary Material 1.
Screenwriting sound and music: Towards a new field of study
Creators: name: Rudolph, Pascal
name: Tieber, Claus
Publisher: name: Humanities Commons
Year: 2024

description: Extensive research in film and media studies on film music and sound has delved into various aspects of their role in cinema, recognizing their significance. However, a crucial element in film production – the screenplay – has often been overlooked in the exploration of sound and music integration. Concurrently, studies on screenwriting have displayed limited interest in the acoustic dimensions of film, creating a research gap where film music studies intersect with screenwriting studies. This Special Issue aims to address this gap by emphasizing the screenplay’s importance in comprehending the role of sound and music in film. This introduction showcases the diverse ways in which music and sound are integrated into screenplays. The ongoing exploration of screenplays for the analysis of sound and music sets the stage for future research endeavours. The editors and authors of this Special Issue advocate for the screenplay as a valuable resource in film music studies, providing innovative insights into the film production process.
Extending IFC Data Structure for Carbon Digital Twin: An IFC Road Example
Creators: name: Xu, Jinying
name: Zhu, Junxiang
name: Yin, Mengtian
name: MacAskill, Kristen
name: Brilakis, Ioannis
Publisher: name: Apollo - University of Cambridge Repository
Year: 2025

description: The construction sector must accelerate progress towards net-zero targets. Current digital twin (DT) frameworks lack integrated carbon data, limiting their effectiveness for sustainability. Industry Foundation Classes (IFC), as an international open data standard, offer the potential to address this gap without exacerbating interoperability issues. This paper proposes extending the IFC schema to include carbon data, focusing on road infrastructure. This study maps the key entities for carbon management to a granular level and adds new carbon property sets to the key entities. It is essential for a carbon digital twin (CDT) that requires exchanging information across lifecycle stages and stakeholders for computational carbon management of road infrastructure.
Intelligent BIM-Integrated Decision Support for Life Cycle Assessment Using Large Language Models
Creators: name: Alavi, Seyedhamidreza
name: Luo, Peihang
name: Kookalani, Soheila
name: Wen, Ya
name: Chen, Weiwei
name: Brilakis, Ioannis
Publisher: name: Digital Frontiers in Buildings and Infrastructure
Year: 2025

description: The construction industry has a profound impact on the environment, consuming significant amounts of energy, water, and raw materials, while also generating waste and greenhouse gas emissions. To mitigate these effects, it is crucial to adopt sustainable construction practices, which are often supported by environmental certification. A key component of these certifications is Life Cycle Assessment (LCA), a process frequently hampered by labor-intensive and timeconsuming manual data handling. This study introduces an enhanced BIM-based decision support system that integrates LCA processes with advanced technologies, including Large Language Models (LLMs). The system automates the extraction, transfer, and analysis of environmental data from BIM models using tools like Revit, Dynamo, and LCA databases. The open-source model "metallama-3.1-8B" is utilized to analyze LCA results, recommend sustainable material alternatives, and facilitate automated scenario comparisons through trade-off analyses. These features enable real-time feedback, dynamic decision-making, and improved optimization of material selection for sustainability. The TR building at UPC serves as a case study to validate the system. The findings indicate significant efficiency gains, enhanced decision-making capabilities, and reduced environmental impacts. By incorporating LLMs, this study addresses existing gaps in BIM-LCA integration and offers a scalable and adaptable framework for sustainable construction, thereby facilitating real-time environmental assessments and achieving certification requirements with greater precision.
Additional file 2 of Impact of early preeclampsia prediction on medication adherence and behavior change: a survey of pregnant and recently-delivered individuals
Creators: name: Cowan, Alison
name: Haverty, Carrie
name: MacDonald, Reece
name: Khodursky, Arkady
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: Supplementary Material 2.
WATER AND WASTEWATER FILTRATION USING POLYELECTROLYTES
Creators: name: Tsao, Hung-ping
name: Wang, Lawrence K
name: Wang, Mu-Hao Sung
Publisher: name: Lenox Institute Press, MA, USA. Lenox.Institute@gmail.com
Year: 2024
Subjects: subject: Autobiographies
subject: Environmental engineering
subject: FOS: Environmental engineering
subject: Colloids
subject: Polyelectrolytes
subject: Biography
subject: Water--Purification--Sand filtration
subject: Collective memory
subject: Water--Purification--Filtration

description: Lawrence K. Wang and Mu-Hao Sung Wang (2024). "Water and wastewater filtration using polyelectrolytes", "Evolutionary Progress in Science, Technology, Engineering, Arts and Mathematics", Lawrence K. Wang and Hung-ping Tsao (editors). Vol. 6, No. 4A, 57 pp. Lenox Institute Press, MA, USA. April 2024. https://doi.org/10.17613/y3zf-9g11 ..... ABSTRACT: The use of polyelectrolytes in the removal of colloidal particles from water and wastewater by filtration has been reviewed and investigated in memory of Dr. William W. Shuster, who was the authors' good friend and the Chairman of Chemical and Bioenvironmental Engineering Department, Rensselaer Polytechnic Institute, Troy, New York, USA.
Specifically pertinent literature on the nature of colloidal materials and the theory related to particle interactions and coagulation has been reviewed and analyzed. Scientific thought on the physical aspects and the chemical aspects of filtration has been considered. References related to the characterization and behavior of multi-media filters as well as single media filters are included in this memoir-style publication. Particular attention has been directed to the applications of polyelectrolytes in water treatment, and industrial wastewater treatment.
sj-pdf-1-smo-10.1177_20503121211029179 – Supplemental material for Barriers toward the practice of healthy behaviors among patients with non-communicable diseases in Gaza Strip, Palestine
Creators: name: Albelbeisi, Ahmed Hassan
name: Albelbeisi, Ali
name: El Bilbeisi, Abdel Hamid
name: Taleb, Mahmoud
name: Takian, Amirhossein
name: Akbari-Sari, Ali
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-pdf-1-smo-10.1177_20503121211029179 for Barriers toward the practice of healthy behaviors among patients with non-communicable diseases in Gaza Strip, Palestine by Ahmed Hassan Albelbeisi, Ali Albelbeisi, Abdel Hamid El Bilbeisi, Mahmoud Taleb, Amirhossein Takian and Ali Akbari-Sari in SAGE Open Medicine
sj-pdf-1-cpx-10.1177_21677026211024644 – Supplemental material for How the Discrepancy Between Prior Expectations and New Information Influences Expectation Updating in Depression—: The Greater, the Better?
Creators: name: Kube, Tobias
name: Kirchner, Lukas
name: Lemmer, Gunnar
name: Glombiewski, Julia Anna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-cpx-10.1177_21677026211024644 for How the Discrepancy Between Prior Expectations and New Information Influences Expectation Updating in Depression—: The Greater, the Better? by Tobias Kube, Lukas Kirchner, Gunnar Lemmer and Julia Anna Glombiewski in Clinical Psychological Science
A qualitative study on how traditional Yeshiva education prepares students for law school
Creators: name: Klein, Reuven Chaim (Rudolph)
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Law schools
subject: Jews--Education
subject: Jewish religious education
subject: Jewish religious education of young people
subject: Jewish religious education--Teaching methods
subject: Jewish religious education--Philosophy
subject: Yeshivas
subject: Questioning
subject: Qualitative research
subject: Interviews

description: This qualitative study explores the potential ways that a traditional Yeshiva education (TYE) helps prepare students for entering and succeeding in law school. The researcher interviewed five rabbi-law professors for their take on this phenomenon and compared the results of those findings with the scholarly literature on the topic to date. Much of that existing scholarly literature focuses on how a Yeshiva education might help students who later switch to law school because of the Yeshiva’s focus on Talmud study, as well as the Yeshiva’s use of the Socratic Method and dyadic Chavrusa study models. To that end, this study sheds light on the various aspects of traditional Yeshiva education that could be beneficial for those pursuing a legal career. The findings demonstrate that there is a broad consensus that Yeshiva education fosters critical thinking and analytical skills through its emphasis on Talmud study, which can be advantageous in comprehending complex legal concepts and arguments. Moreover, exposure to aspects of the law school culture and methodology during Yeshiva education can arguably prepare students for its use by law teachers in law school, contributing to their ability to productively engage in thoughtful and probing discussions.
sj-pdf-1-aic-10.1177_0310057X21989715 - Supplemental material for Māori health outcomes in an intensive care unit in Aotearoa New Zealand
Creators: name: Slim, M Atif Mohd
name: Lala, Hamish M
name: Barnes, Nicholas
name: Martynoga, Robert A
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-aic-10.1177_0310057X21989715 for Māori health outcomes in an intensive care unit in Aotearoa New Zealand by M Atif Mohd Slim in Anaesthesia and Intensive Care
HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model
Creators: name: Nguyen-Hoai, Tam
name: Kobelt, Dennis
name: Hohn, Oliver
name: Vu, Minh D.
name: Schlag, Peter M.
name: Dörken, Bernd
name: Norley, Stephen
name: Lipp, Martin
name: Walther, Wolfgang
name: Pezzutto, Antonio
name: Westermann, Jörg
Publisher: name: Robert Koch-Institut
Year: 2012
Subjects: subject: DNA vaccination
subject: CTL response
subject: gene gun
subject: HER2/neu
subject: jet injector
subject: 610 Medizin

description: DNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal and dermal layers of the skin are characterized by an abundance of antigen-presenting cells (APCs). The aim of our study was to compare tumor protection as obtained by two different methods of intradermal DNA delivery (gene gun and jet injector) in a well-established HER2/neu mouse tumor model. BALB/c mice were immunized twice with a HER2/neu-coding plasmid by gene gun or jet injector. Mice were then subcutaneously challenged with HER2/neu+ syngeneic D2F2/E2 tumor cells. Protection against subsequent challenges with tumor cells as well as humoral and T-cell immune responses induced by the vaccine were monitored. Gene gun immunization was far superior to jet injector both in terms of tumor protection and induction of HER2/neu-specific immune responses. After gene gun immunization, 60% of the mice remained tumor-free until day 140 as compared with 25% after jet injector immunization. Furthermore, gene gun vaccination was able to induce both a strong TH1-polarized T-cell response with detectable cytotoxic T-lymphocyte (CTL) activity and a humoral immune response against HER2/neu, whereas the jet injector was not. Although the disadvantages that were associated with the use of the jet injector in our model may be overcome with methodological modifications and/or in larger animals, which exhibit a thicker skin and/or subcutaneous muscle tissue, we conclude that gene gun delivery constitutes the method of choice for intradermal DNA delivery in preclinical mouse models and possibly also for the clinical development of DNA-based vaccines.
The Importance of Archives in the Polar Information Environment: where do unaffiliated international polar organizations archive their records?
Creators: name: Lund, Peter
name: Kissel, Laura
name: Campbell, Sandy
Publisher: name: Apollo - University of Cambridge Repository
Year: 2025

description: Archives are usually designed to collect the records of the organization with which they are affiliated. International polar organizations without a specific institutional affiliation may not have an obvious place to archive their records. For example, the Polar Libraries Colloquy (PLC) and the University of the Arctic Thematic Network on the Decolonization of Arctic Library and Archives Metadata (DALAM) are fortunate to have their records collected at the Alaska and Polar Regions Collections & Archives (APRCA) at University of Alaska, Fairbanks Some organizations assume that the Internet Archive is collecting and preserving everything from their websites, but that is not accurate. Others may be relying on private servers for long-term storage or may not have considered the need to preserve their records. Traditional archives have a mandate to curate and permanently preserve records that fall within their collection policies. Many traditional archives are heavily print based with processes for preserving electronic records not yet fully defined. Many international polar organizations operate digitally. Archives which might be willing to accept records from these organizations may not yet have procedures in place that would allow them to manage their electronic records. This study addresses the issues and challenges facing small unaffiliated international polar organizations (UIPO) that need to archive their records. Potential solutions may include increased education about the need to archive, as well as identifying repositories that may accept these records.
Male Virility and Biblical Power Dynamics
Creators: name: Klein, Reuven Chaim (Rudolph)
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Critical theory
subject: Sex
subject: Bible. Old Testament
subject: Rabbinical literature
subject: Talmud
subject: David, King of Israel
subject: Moses (Biblical leader)
subject: Polemics in the Bible
subject: Orgasm
subject: Jael (Biblical figure)

description: This paper outlines an investigation into three instances within the Babylonian Talmud where biblical stories of sexual encounters are interpreted as multi-coital events involving figures like King David, Bathsheba, Zimri, Cozbi, Sisera, and Jael. Despite the absence of explicit descriptions of sexual encounters in the Bible, the Talmud confidently asserts the occurrence of multiple acts of coitus in each case, without explaining how this interpretation contributes to understanding the narratives. The study aims to elucidate a common theme across these episodes, positing that the motif of "sex as power" underpins the Talmud's unconventional assertions. It argues that male biblical characters utilized their supposed multi-coital abilities as a means of showcasing dominance and power over others, circumventing physiological constraints to assert control. The concept of "sex as power" frames sexual activity as a tool for asserting dominance, control, or influence, with individuals leveraging their sexual prowess to achieve specific objectives. In these instances, women serve as passive recipients, while men use sexual performance as a strategic display of status and dominance. By contextualizing these episodes within their broader biblical and rabbinic discourse, the study examines the background of each narrative, introduces Talmudic interpretations of multiple coital acts, and explores their alignment with the motif of "sex as power." It concludes by addressing the inflated nature of the Talmud's assertions within the literary convention of "stock" numbers, providing insight into the interpretive lens through which these stories are understood.
A low cosmic-ray ionisation rate in the prestellar core Ophiuchus/H-MM1. Mapping of the molecular ions ortho-H2D+, N2H+, and DCO+
Creators: name: Harju, Jorma
name: Vastel, Charlotte
name: Sipilae, Olli
name: Redaelli, Elena
name: Caselli, Paola
name: Pineda, Jaime E.
name: Belloche, Arnaud
name: Wyrowski, Friedrich
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: (abridged) We have mapped the prestellar core H-MM1 in Ophiuchus in rotational lines of ortho-H2D+ (oH2D+), N2H+, and DCO+ at the wavelength 0.8 mm with the Large APEX sub-Millimeter Array (LAsMA) multibeam receiver of the Atacama Pathfinder EXperiment (APEX) telescope. We also ran a series of chemistry models to predict the abundance distributions of the observed molecules, and to estimate the effect of the cosmic-ray ionisation rate on their abundances. The three line maps show different distributions. The oH2D+ map is extended and outlines the general structure of the core, while N2H+ mainly shows the density maxima, and the DCO+ emission peaks are shifted towards one edge of the core where a region of enhanced desorption has been found previously. According to the chemical simulation, the fractional oH2D+ abundance remains relatively high in the centre of the core, and its column density correlates strongly with the cosmic-ray ionisation rate. Simulated line maps constrain the cosmic-ray ionisation rate per hydrogen molecule to be low, between 5e-18/s and 1e-17/s in the H-MM1 core. This estimate agrees with the gas temperature measured in the core. Modelling line emission of oH2D+ provides a straightforward method of determining the cosmic-ray ionisation rate in dense clouds, where the primary ion, H3+, is not observable.
description: accepted for publication in Astronomy & Astrophysics
Ang Espirituwal na Tao ay mga tao - New Model-theory w/ New Categorization based on Practical Use (W. James)and Creative-fruiitful Spirituality = Counterpoint to Materialist "Lahat ng espirituwalidad ay hindi totoo!" + mga espirituwal na karanasan bilang
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2024
Subjects: subject: Science--Philosophy
subject: Spirituality
subject: Blaan (Philippine people)
subject: Spirituality--Christianity
subject: Tboli (Philippine people)
subject: McGill University. Faculty of Religious Studies
subject: Conference on Science, Philosophy and Religion in Their Relation to the Democratic Way of Life
subject: International Union of the History and Philosophy of Science
subject: Psychology
subject: FOS: Psychology
subject: Institut filosofii (Rossiĭskai︠a︡ akademii︠a︡ nauk)

description: Nababalot sa Abstractions: Mula sa pananaliksik at karanasan, madaling makita na ang espiritwalidad ay nasangkot sa mga abstraction: mga kapangyarihan, pagiging perpekto, supernatural, hindi makatotohanan, walang limitasyong kaalaman, mga pang-unawa sa bolang kristal, atbp. Sumagot si Dr Stephen Farra ng "Magandang maikling papel - maalalahanin at sa ang punto: Ang kawalan ng paniniwala sa "free will" (volitional life direction) ay karaniwang humahantong sa isang pakiramdam ng kawalan ng kabuluhan. kawalan ng pag-asa, at hindi etikal na personal na pag-uugali. Ang aming mga paradigma ay ang aming paraan ng pagtugon sa Reality, ngunit ang mga ito ay Hindi Reality. Gaya ng iminumungkahi ni Charles Peck, Jr., naliligaw tayo sa sarili nating abstraction!" Bagama't nakakainip, - mahalaga ang mga pangunahing siyentipikong pamamaraan. "Nagiging Tayo ang iniisip natin!" – Buddha Isang Pivotal na Tanong kung paano natin nakikita ang mundo - ay hindi lamang mahalaga at mahahalagang tanong-isyu - ngunit mahalaga. Kategorya 1. Spirituality of Compassion: The Oxford Handbook on Compassion: "Ang pakikiramay sa iba at panlipunang suporta ay may halaga ng kaligtasan at mga benepisyo sa kalusugan…. (p. 171) 2. Musical Spirituality . Sina Shulkin at Raglan ay nagmamasid na "Ang aming ebolusyon ay mahigpit na nakatali sa musika at sa katawan bilang isang instrumento (hal., pagpalakpak). Ang musika, bukod sa iba pang mga bagay, ay nakakatulong upang mapadali ang panlipunang kooperatiba at magkakaugnay na pag-uugali." 3. Prophecy, Poetry, & Spirituality - Creativity, Transcendence: "Ang propeta ay isang makata. Ang kanyang karanasan ay kilala ng mga makata. Ang alam ng mga makata bilang poetic inspiration; ang mga propeta ay tinatawag na banal na paghahayag" - Heschel 4. Kapwa-loob pro- panlipunang kaugalian/espirituwalidad Kapwa at Relational Spirituality