cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of coordination environment on transition metal mediated dioxygen bond formation, stabilization and cleavage: A mechanistic study
Creators: name: Dutta, Kuheli
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Katalysator
subject: Klein-Moleküle Aktivierung
subject: Spektroskopie
subject: Kinetik
subject: Catalyst
subject: Small molecule activation
subject: Spectroscopy
subject: Kinetics
subject: 546 Anorganische Chemie

description: Übergangsmetall-Oxo, -Peroxo und -Oxyl-Intermediate gelten als essentielle Zwischenstufen von biochemischen Transformationen, welche die Bildung und Spaltung der Disauerstoff -Bindung involvieren. Biomimetische Untersuchungen der katalytisch aktiven Zentren von Enzymen dienen dem Verständnis der verschiedenen Mechanismen katalytischer Reaktionen in biochemischen Systemen. Weiterhin können ebenjene Studien einzigartige Einblicke in den Einfluss scheinbar geringer Variationen der koordinativen Umgebung in die Produktselektivität, der katalytischen Aktivität und der Mechanismen ablaufender Reaktionen liefern. Die Darstellung und Charakterisiserung dieser kritischen Zwischenstufen ist deshalb ein wertvolles Werkzeug zur Aufklärung und Verständnis mechanistischer Abläufe. Aus den so gewonnen Erkentnissen erwächst das Potential neue und optimierte Katalysatoren unter anderem für die Spaltung und Bildung von Disauerstoff entwickeln zu können. Die in der vorliegenden Dissertation beschriebenen Arbeiten zeigen deutlich den Einfluss scheinbar gerinfügiger Änderungen des Ligandensystems bzw. des Reaktionsmediums auf die Bildung, Stabilisierung und Spaltung der Disauerstoff-Bindung.
description: Transition metal-oxo, -peroxo, -oxyl intermediates have been proposed as key reactive intermediates in biochemical transformations relevant to dioxygen bond formation and cleavage. Biomimetic studies of relevant enzyme active sites help us to understand the different mechanistic pathways operating in biological systems. Moreover, biomimetic studies also provide us with unique insights into the effect of subtle changes in the coordination environment that can influence the product-selectivity, catalytic efficiency and reaction mechanism. The generation and characterization of these crucial reactive intermediates, therefore, provide a valuable tool for mechanistic understanding and consequently, aid in the development of new and improved catalysts for dioxygen bond formation and cleavage. Therefore, in this thesis, we show how subtle changes in the ligand framework or reaction medium can greatly influence the fate of the dioxygen bond, its formation, stabilization and cleavage.
Intelligente Prozesseinrichtung anhand emittierter akustischer Oberflächenwellen für die direkte Laserinterferenzstrukturierung
Creators: name: Muntschick, Clarita
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2022
Subjects: DLIP
Funktionalisierung
Körperschall

description: Die direkte Laserinterferenzstrukturierung (DLIP) ist einer der effizientesten Ansätze, um Wohldefinierte periodische Mikrostrukturen zu erzeugen. Diese strukturierten Oberflächen ahmen natürliche Äquivalente nach, wie z.B. den Lotuseffekt für selbstreinigende Eigenschaften oder die Haifischhaut für geringere Reibung und werden in der Industrie eingesetzt. Die Qualität der gewünschten Oberflächen hängt von verschiedenen topologischen Parametern ab, jedoch insbesondere von der erreichten Strukturtiefe. Ansätze zur Prozessüberwachung und ‐analyse auf Basis der akustischen Prozessemission wurden bereits entwickelt, jedoch gibt es noch keine Lösung, die Strukturtiefe automatisiert zu ermitteln und einzustellen. Dies würde den Zeitaufwand bei der Einführung und Verarbeitung neuer Werkstoffe deutlich reduzieren. Im Rahmen dieser Arbeit wird die Messung der Körperschallemission bei der direkten Laserinterferenzstrukturierung als ein möglicher Lösungsansatz für dieses Problem untersucht und bewertet. Dies beinhaltet das Detektieren des Körperschalls für Titan und Edelstahl bei Einzelpulsablation und Überlappung der Pulse auf dem Material. Ausgewertet werden die aus dem transienten Körperschallsignal extrahierten Parameter sowie die resultierende Strukturtiefe. Dadurch konnte erfolgreich gezeigt werden, dass mithilfe der Körperschallanalyse die materialspezifische Ablationsgrenze ermittelt werden kann und der emittierte Körperschall von der strukturierten Fläche und dem entstandenen Plasma abhängig ist.
Publicising OR projects in the media
Creators: name: Clarke, Stephen
Publisher: name: Swinburne
Year: 2024

description: Promoting the results of OR projects in the mass media raises the profile of OR within the community. The author has been successful in gaining widespread publicity for his research into sport. This publicity has promoted the OR and statistics profession as well as the author's department and institution to possible users and sponsors of the research, future students and the general public. Similar publicity is possible for many staff research or student projects, and studies conducted for industrial clients. This paper discusses examples and strategies that have been employed.
"Morgen, Morgen! Nur nicht heute!"  Il lavoro dei religiosi secondo la legislazione tedesca
Creators: name: Testa Bappenheim, Stefano
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: SOMMARIO: Introduzione - 1. Indicazione ad alcune questioni che si possono
porre relative ad aspetti tributari o di previdenza sociale - 2. Nessun legame di  lavoro con i contratti di servizio - 2.1. Requisiti per l'Istituto - 3. Natura giuridica del  Gestellungsvertrag - 3.1. Terminologia - 3.2. Gestellungsvertrag: costruzione illegale  o contratto sui generis? - 4. Cambiamenti della giurisprudenza - 41. Giurisprudenza del  Reichsfinanzhof - 4.2. Giurisprudenza del  Bundesfinanzhof - 4.3. La prassi dell’autorità finanziaria - 5. Aspetti prettamente giuridici dei Gestellungsverträge -
5.1. Questioni giuridiche generali sulla costituzione aziendale relativa all’attività dei professi in un istituto estraneo all’Ordine.

description: Stato, Chiese e pluralismo confessionale, 2007: 11 luglio
Il progetto di Legge Tjul’kin   per modificare la legislazione sulle associazioni religiose
Creators: name: Codevilla, Giovanni
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: Il contributo è destinato alla pubblicazione nel prossimo numero della rivista La nuova Europa, edita dal Centro Studi Russia Cristiana.
description: Stato, Chiese e pluralismo confessionale, 2007: 16 luglio
Ökobilanz der Herstellung verfahrenstechnischer Power-to-X-Anlagen in frühen Planungsphasen
Creators: name: Lozanovski, Aleksandar
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2021
Subjects: Ökobilanz
Power-to-X
Verfahrenstechnik
CO2-Nutzung
Life Cycle Assessment

description: In Power-to-X-Anlagen wird Energie als Rohstoff genutzt, um Kohlenwasserstoffe für die chemische Industrie, Luftfahrt, Langstreckenverkehr und als saisonaler Langfristspeicher zu erzeugen. Wenn erneuerbare Energien eingesetzt werden, ist die Betriebsphase der Power-to-X-Anlagen treibhausgasarm. Zudem werden die Emissionen aus der Anlagenherstellung relevant und müssen für eine vollständige Ökobilanz erfasst werden. Die ÖkoVerfPlan-Methode (Ökobilanz der Herstellung verfahrenstechnischer Anlagen in frühen Planungsphasen) ermöglicht die Erfassung der Anlagenherstellung mit vertretbarem Aufwand in einer frühen Planungsphase, in der sich die meisten Power-to-X-Anlagen derzeit befinden. In dieser Arbeit werden verschiedene Vorgehensweisen beschrieben, wie die Umweltwirkungen der Hauptanlagenteile, wie zum Beispiel Kolonnen, Reaktoren, Kompressoren etc., berechnet werden können. Neben den Hauptanlagenteilen werden Umweltzuschlagsfaktoren bereitgestellt, um noch nicht näher definierte Nebenanlagenteile wie Fundamente, Rohrleitungen, Gebäude, etc. in der Ökobilanz zu berücksichtigen. Die ÖkoVerfPlan-Methode ermöglicht es, jegliche Arten verfahrenstechnischer Anlagen ökobilanziell zu erfassen.
Tayassuidae INDET.
Creators: name: Maguire, Kaitlin Clare
name: Schmitz, Joshua X. Samuels and Mark D.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Artiodactyla
Tayassuidae

description: TAYASSUIDAE INDET.
Referred specimens —Partial dentary with m1, m2, JODA 301; partial molar, JODA 302; partial dentary with p2 and p3(?), JODA 2230; molar, JODA 2238; molar, JODA 2239; molar, JODA 2240; premolar, JODA 2241; premolar, JODA 2242; deciduous premolar, JODA 2244; partial molar, JODA 2245; partial molar, JODA 2246; p2, JODA 2324; premolar, JODA 2341; M3, JODA 2342; premolar, JODA 2349; premolar, JODA 2391. From JDNM-71: molar fragment, JODA 13946. From UCMP -884: m3, UCMP 1628.
Occurrence —JDNM-4*, JDNM-71, UCMP -884.
Remarks —These specimens can be attributed to Tayassuidae; however, there is no locality information because they were collected by the Weatherfords or park rangers during the first years of JODA or are assigned to a general locality number. Therefore, it is unclear which formation they are from. The specimens are all too big to belong to “ Cynorca,” as described above, but lack the diagnostic characters that would be required to assign them to another genus. They fall within the size range of Dyseohyus fricki Stock, 1937 and “ Prosthennops ” xiphidonticus Barbour, 1925, two Barstovian species (Wright 1998); however, they also fall within the size range of Hemphillian peccaries such as Platygonus oregonensis Colbert, 1938, which is known from and common in the Rattlesnake Formation (Merriam et al. 1925). A lower right m3, UCMP 1628, was collected from locality -884 (Mascall Misc. 2). It has an anteroposterior length of 16.48 mm and a transverse width of 10.87 mm, the same size as D. fricki, the locality information is minimal and it is unclear if the specimen was found in the Mascall Formation or the Rattlesnake Formation.
A small tayassuid molar fragment (JODA 13946) was collected at JDNM-71 Rock Creek locality from the lower Mascall unit, demonstrating the stratigraphic persistence of peccaries throughout the lower and middle units of the formation.
description: Published as part of Maguire, Kaitlin Clare & Schmitz, Joshua X. Samuels and Mark D., 2018, The fauna and chronostratigraphy of the middle Miocene Mascall type area, John Day Basin, Oregon, USA, pp. 1-51 in PaleoBios 35 on page 31, DOI: 10.5070/P9351037578, http://zenodo.org/record/13749829
La delibazione delle sentenze ecclesiastiche  ed i poteri istruttori della Corte d’Appello
Creators: name: Marchei, Natascia
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: Il contributo è destinato alla pubblicazione nella rivista  Famiglia, Persone e
Successioni, edita dalla Utet.SOMMARIO: 1. Il caso – 2. Gli orientamenti della giurisprudenza di legittimità – 3. Il limite del riesame del merito ed i poteri della Corte d’Appello: brevi
considerazioni conclusive.
description: Stato, Chiese e pluralismo confessionale, 2007: 23 luglio
title: Klimaschutz im Verkehr: Neuer Handlungsbedarf nach dem Pariser Klimaschutzabkommen
title: Klimaschutz im Verkehr: Neuer Handlungsbedarf nach dem Pariser Klimaschutzabkommen
titleType: AlternativeTitle
Creators: name: Bergk, Fabian
name: Knörr, Wolfram
name: Lambrecht, Udo
Publisher: name: Umweltbundesamt
Year: 2017
Subjects: subject: Klimaschutz
subject: Energieverbrauch
subject: Verkehrswesen
subject: Treibhausgasemission
subject: Emissionsminderung
subject: Verkehrsemission
subject: Verkehrsaufwand
subject: Güterverkehr
subject: Bundesregierung
subject: Energiekonzept
subject: Automobilität
subject: Klimaschutzabkommen
subject: Pariser-Übereinkommen
subject: Verkehrsemissionen
subject: Verkehr

description: Mobilität ist unverzichtbarer Teil des täglichen Lebens. Mobilität ist aber auch einer der größten Verursacher von Treibhausgasen in Deutschland. Was muss geschehen, um die Treibhausgasemissionen des Verkehrs kurz- und mittelfristig zu senken? Wie kann langfristig in Deutschland ein treibhausgasneutraler Verkehr erreicht werden? Sind die deutschen Klimaschutzziele für den Verkehr ambitioniert genug? Das vorliegende Papier gibt darauf Antworten. Es beschreibt den Handlungsbedarf der nächsten Jahre, um die Entwicklung des Verkehrssektors in Deutschland mit den Anforderungen des Pariser Klimaschutzabkommens und des „Klimaschutzplans 2050“ der Bundesregierung zur Deckung zu bringen. Es stellt Maßnahmen vor, mit denen die Treibhausgasemissionen des Verkehrs schnell deutlich gesenkt werden können und die so einen Beitrag dazu leisten, die in Paris beschlossenen Klimaschutzziele auch im Verkehrssektor in Deutschland sicher zu erreichen.Das Paris-Abkommen will den Anstieg der durchschnittlichen Erdtemperatur auf deutlich unter 2°C begrenzen und langfristig nur noch „Netto-Null-Emissionen“ zulassen. Die Umsetzung des Abkommens stellt alle vor große Herausforderungen: Die Höhe des globalen Emissionsbudgets ist bei einem Temperaturziel von maximal 2 °C extrem knapp bemessen. Deutschland muss noch vor dem Jahr 2030 einen Großteil seiner Emissionen einsparen. Dieser Handlungsdruck spiegelt sich in den Zielen des deutschen Klimaschutzplans oder im europäischen Rahmen für die ⁠Klima⁠- und Energiepolitik allerdings nicht wieder. Anders gesagt: Deutschland und die EU müssen ihre Anstrengungen für den ⁠Klimaschutz⁠ deutlich intensivieren. Dabei hat auch der Verkehr seinen Beitrag zu leisten. Die Klimaschutzziele des Paris-Abkommens sind sehr ambitioniert, doch die Instrumente zu ihrem Erreichen stehen bereit – sie müssen jedoch umgehend eingeführt und konsequent umgesetzt werden.
Entwicklung einer Methode zur Bewertung der Zugänglichkeit von Ressourcen im Rahmen der Kreislaufwirtschaft
Creators: name: Graf, Roberta
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2022
Subjects: Nachhaltigkeit
Ressourcen
Kreislaufwirtschaft
Versorgungssicherheit
Technosphäre
Vorratsmodell

description: Der Zugang zu Ressourcen ist für nachhaltige Wirtschaftsstrategien von strategischer Bedeutung. Um bei wachsender Nachfrage einer unsicheren Versorgungslage zu begegnen und dabei die natürlichen Ressourcen zu schonen, ist die Förderung der Kreislaufwirtschaft ein Lösungsansatz. Durch die hierbei angestrebte Schließung der Stoffkreisläufe gewinnen Ressourcenvorräte der Technosphäre an Bedeutung und beeinflussen somit die Informationsgrundlage. Ausgangslage dieser Arbeit ist die Frage, welche Ressourcenvorräte künftig zugänglich sein werden und welche Potentiale dadurch gehoben werden können. Das aus der entwickelten Methode resultierende Vorratsmodell und die entstehenden Potentialaussagen ermöglichen eine Erweiterung der Wissensbasis bezüglich der Zugänglichkeit von Vorräten im Rahmen der Kreislaufwirtschaft. In dieser Arbeit wird die Bewertungsmethode beispielhaft für Kupfer angewendet. Die Methode bietet einen Beitrag zur Erweiterung der Vorratsbetrachtung und kann genutzt werden, um hebbare Ressourcen-Potentiale zu identifizieren und nachhaltigere Materialentscheidungen zu treffen.
Disciplinarità confessionale e stato di diritto
Creators: name: Bellini, Piero
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: Testo provvisorio della relazione al Convegno “La Carta e la Corte” che si terrà presso la Facoltà di Giurisprudenza dell’Università di Ferrara il 26 e 27 ottobre 2007.

description: Stato, Chiese e pluralismo confessionale, 2007: 24 luglio
Enhanced browsing in digital libraries: three new approaches to browsing in Greenstone
Creators: name: McKay, Dana
name: Shukla, Preeti
name: Hunt, Rachael
name: Cunningham, Sally Jo
Publisher: name: Swinburne
Year: 2024

description: Browsing is part of the information-seeking process, used when information needs are ill-defined or unspecific. Browsing and searching are often interleaved during information seeking to accommodate changing awareness of information needs. Digital libraries often do not support browsing. Described here are three browsing systems created for the Greenstone digital library software.
La sage-femmerie à travers le temps au Québec : perceptions d'étudiantes en techniques infirmières sur la naissance et la pratique des sages-femmes.
Creators: name: Normand, Josée.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Health Sciences, Obstetrics and Gynecology.

description: Abstract Not Available.
Le minoranze islamiche nella Bulgaria post-comunista: ingerenze  statali e libertà confessionale
Creators: name: Fantelli, Paola
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: Contributo segnalato dal Prof. Paolo Moneta, ordinario di Diritto ecclesiastico
nella facoltà di Giurisprudenza dell’’Università di PisaSOMMARIO: 1. Profili istituzionali delle relazioni tra Stato e confessioni religiose nella Bulgaria post-comunista: la posizione dell’Islam. 2. Le ingerenze del Governo bulgaro nell’organizzazione interna delle rappresentanze islamiche secondo la Corte di Strasburgo. 3. Alcune osservazioni sull’ingresso della Bulgaria nell’U.E. e sulle problematiche dell’Islam bulgaro – balcanico.
description: Stato, Chiese e pluralismo confessionale, 2007: 30 luglio
title: Личный фонд профессора Г. Г. Писаревского в Отделе рукописей Российской государственной библиотеки
Creators: name: Черказьянова, И. В.
Publisher: name: Реноме
Year: 2018

description: В статье дается характеристика личного фонда историка Г. Г. Писаревского, который хранится в Отделе рукописей Российской государственной библиотеки. Документы отражают его московский и варшавский период жизни, дают представление о научной и преподавательской работе, о его окружении, бытовых условиях жизни. В фонде находятся десятки автографов известных российских ученых, особую ценность представляют письма Д. В. Цветаева.

Ключевые слова: Григорий Григорьевич Писаревский, Дмитрий Владимирович Цветаев, Российская государственная библиотека, архив, университет, магистерская диссертация, Москва, Варшава.
Constrained Optimal Experimental Design: Theory, Algorithm and Applications
Creators: name: Seufert, Philipp
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2024
Subjects: Optimal experimental design
Adaptive algorithms
Nonlinear programming
Semi-infinite programming
Bilevel optimization

description: While the literature on optimal experimental design (OED) is primarily concerned with unconstrained problems, it is also of interest to restrict individual experiments, certain design quantities, or even the entire experimental plan. A classic approach to OED models the problem as an unconstrained optimization problem over the infinite dimensional space of probability measures. This thesis introduces a general framework for constrained OED problems and discusses optimality criteria in form of saddle point conditions. Particular attention is paid to the required constraint qualifications. For the numerical solution of such constrained infinite-dimensional nonlinear OED problems this thesis proposes an adaptive discretization scheme, utilizing the derivative of the Lagrangian function. Furthermore, this thesis discusses the multi-criteria OED problem and presents algorithmic schemes for convex and non-convex objective functions. Finally, the algorithms are illustrated on an application example from chemical process engineering.
Vilipendio religioso e satira: “nuove” incriminazioni e “nuove”  soluzioni giurisprudenziali
Creators: name: Siracusano, Placido
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: SOMMARIO: 1. Considerazioni introduttive – 2. Il vilipendio religioso nel prisma della libertà di manifestazione del pensiero – 3. Le nuove coordinate penalistiche del vilipendio di ministri di culto – 4. Segue: il bene giuridico tutelato tra variegate proposte dottrinarie ed una “sorprendente” Carta dei valori – 5. Il diritto di satira: fondamento, limiti, applicazioni – 6. Le  - non interamente -  condivisibili soluzioni della sentenza.

description: Stato, Chiese e pluralismo confessionale, 2007: 30 luglio
Merycoidodontidae INDET.
Creators: name: Maguire, Kaitlin Clare
name: Schmitz, Joshua X. Samuels and Mark D.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Artiodactyla
Merycoidodontidae

description: MERYCOIDODONTIDAE INDET.
Referred specimens —From JDNM-4*: left m1 and partial m 2 in dentary fragment, JODA 2361. From V 4834: left canine, JODA 4254; astragalus, UCMP 39313.
Occurrence —JDNM-4*, V 4834 Mascall 20
Remarks —JODA 2361 is too large for Ticholeptus and lacks significant diagnostic material (ap= 18.09 mm, t= 12.59 mm). JODA 4264 is a complete canine, but not diagnosable to genus or species. UCMP 39313 was reported by Downs (1956) (ap= 33.8 mm and t=22.0 mm).
description: Published as part of Maguire, Kaitlin Clare & Schmitz, Joshua X. Samuels and Mark D., 2018, The fauna and chronostratigraphy of the middle Miocene Mascall type area, John Day Basin, Oregon, USA, pp. 1-51 in PaleoBios 35 on page 34, DOI: 10.5070/P9351037578, http://zenodo.org/record/13749829
Understanding Variability in Modern Cross-Border Shopping Occasions
Creators: name: Lever, Michael
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: subject: Modern
subject: Cross border shopping
subject: Variability
subject: Trajectories
subject: Technology
subject: Canada
subject: USA
subject: Tourism
subject: FOS: Economics and business
subject: Network

description: Throughout history, consumers have crossed borders for various purposes. The emergence of e-commerce and digital technologies has made it easier than ever for people to shop online with merchants across the world. The purpose of this thesis is to demonstrate the variations of cross-border shopping motivations, the changes that occur due to advancements in various technologies, and the spatial patterns and mapped occasions that appear from each cross-border shopping episode. A qualitative, ethnographic approach has been used, and provides a detailed examination of the contemporary cross-border shopping landscape. Findings assist in developing this framework, after conducting detailed participant observation and interviews. The results indicate a range of variability stemming from generational, social, and personal differences, along with technological drivers of change. Trajectories of cross-border shopping occasions and a network model of modern cross-border shopping occasions are provided and detailed. Implications and future research are also discussed.
Quantitative assessment of coronary plaque volume change related to triglyceride glucose index: The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry
Creators: name: Won, Ki-Bum
name: Lee, Byoung K.
name: Park, Hyung-Bok
name: Heo, Ran
name: Lee, Sang-Eun
name: Rizvi, Asim
name: Lin, Fay Y.
name: Kumar, Amit
name: Hadamitzky, Martin
name: Kim, Yong-Jin
name: Sung, Ji M.
name: Conte, Edoardo
name: Andreini, Daniele
name: Pontone, Gianluca
name: Budoff, Matthew J.
name: Gottlieb, Ilan
name: Chun, Eun J.
name: Cademartiri, Filippo
name: Maffei, Erica
name: Marques, Hugo
name: De Araújo Gonçalves, Pedro
name: Leipsic, Jonathon
name: Shin, Sanghoon
name: Choi, Jung H.
name: Virmani, Renu
name: Samady, Habib
name: Chinnaiyan, Kavitha
name: Raff, Gilbert L.
name: Stone, Peter H.
name: Berman, Daniel S.
name: Narula, Jagat
name: Shaw, Leslee J.
name: Bax, Jeroen J.
name: Min, James K.
name: Chang, Hyuk-Jae
Publisher: name: BioMed Central
Year: 2020

description: Background: The association between triglyceride glucose (TyG) index and coronary atherosclerotic change remains unclear. We aimed to evaluate the association between TyG index and coronary plaque progression (PP) using serial coronary computed tomography angiography (CCTA). Methods: A total of 1143 subjects (aged 60.7 ± 9.3 years, 54.6% male) who underwent serial CCTA with available data on TyG index and diabetic status were analyzed from The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry. PP was defined as plaque volume (PV) (mm3) at follow-up minus PV at index > 0. Annual change of PV (mm3/year) was defined as PV change divided by inter-scan period. Rapid PP was defined as the progression of percent atheroma volume (PV divided by vessel volume multiplied by 100) ≥ 1.0%/year. Results: The median inter-scan period was 3.2 (range 2.6–4.4) years. All participants were stratified into three groups based on TyG index tertiles. The overall incidence of PP was 77.3%. Baseline total PV (group I [lowest]: 30.8 (0.0–117.7), group II: 47.2 (6.2–160.4), and group III [highest]: 57.5 (8.4–154.3); P < 0.001) and the annual change of total PV (group I: 5.7 (0.0–20.2), group II: 7.6 (0.5–23.5), and group III: 9.4 (1.4–27.7); P = 0.010) were different among all groups. The risk of PP (odds ratio [OR] 1.648; 95% confidence interval [CI] 1.167–2.327; P = 0.005) and rapid PP (OR 1.777; 95% CI 1.288–2.451; P < 0.001) was increased in group III compared to that in group I. TyG index had a positive and significant association with an increased risk of PP and rapid PP after adjusting for confounding factors. Conclusion: TyG index is an independent predictive marker for the progression of coronary atherosclerosis. Clinical registration ClinicalTrials.gov NCT02803411
Quale laicità
Creators: name: Colaianni, Nicola
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: Recensione a C. CARDIA, Le sfide della laicità. Etica, multiculturalismo, islam,
Edizioni San Paolo, Cinisello Balsamo, 2007, pp. 202, destinata alla pubblicazione sulla rivista “Laicità”, Torino, n. 3 del 2007.
description: Stato, Chiese e pluralismo confessionale, 2007: 10 settembre
Generalized Impairment of CD8+ T-cells in HCV Mono- and HIV-HCV Co-infection
Creators: name: Burke, Stephanie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Hepatitis C Virus
CD8+ T cell
HIV

description: Chronic hepatitis C virus (HCV) infection has global effects on the immune system. CD8+ T-cells, responsible for viral clearance and control, are dysfunctional for as yet unknown reasons. It is hypothesized that IL-7 signaling pathway deficiencies contribute to this impairment. Blood-derived CD8+ T-cells in chronic HCV mono- and HIV-HCV co-infection had lower IL-7-induced activation of STAT5 and production of Bcl-2, and lower proliferation in co-infection, compared to controls. Lower Bcl-2 production was also associated with increased fibrosis. These changes were independent of the IL-7 receptor α expression and suppressor of cytokine signaling 1 or 3 expression. Intrahepatic CD8+ T-cells in HCV-infection did not activate STAT5 above basal levels with cytokine stimulation and had lower Bcl-2 expression than blood-derived cells. In conclusion, bulk CD8+ T-cells were impaired in response to IL-7 and the IL-7 signaling pathway may be one mechanism by which CD8+ T-cells are impaired in chronic HCV infection.
title: Методы реставрации бумажных калек, проверенные временем, в ЛКРД Санкт-Петербургского филиала Архива РАН
Creators: name: Олейник, Л. Г.
name: Швиль, Л. М.
Publisher: name: Реноме
Year: 2018

description: Рисунки Б. С. Якоби выполнены итальянским карандашом в ХIХ веке на промасленных кальках. План лесонасаждений Бабинской дачи — калька, тушь, цветные карандаши — ХХ век. Кальки были хрупкие и распались на отдельные фрагменты. В процессе реставрации более 35 лет назад осыпающийся карандаш был закреплен, частично удалена масляная пропитка. Документы приобрели целостность и долговечность и в настоящее время находятся в хорошем состоянии.

Ключевые слова: реставрация, калька, мониторинг.
A Meta-analytic Approach for Testing Evolutionary Hypotheses of Acquired Resistance in Metastatic Cancer
Creators: name: Bhardwaj, Kalpana
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: cancer
resistance evolution
chemotherapy
meta-analysis
combination therapy
monotherapy
clinical trial

description: Nowell (1976) first proposed that unless cytotoxic cancer therapy eradicates all tumor cells, genetic or heritable variation within heterogeneous tumors will inevitably lead to the evolution of chemotherapeutic resistance through clonal selection. This evolutionary hypothesis was formalized by Goldie and Coldman (1979), who developed one of the earliest mathematical kinetic models of resistance evolution in neoplasms. Their model predicted that the likelihood of response and cure would be increased in combination vs single agent cytotoxic therapies. In a later study, Gardner (2002) developed a computational kinetic model to predict chemotherapeutic combinations, doses, and schedules most likely to result in patient response and prolonged life. This model predicts that combination therapy involving both cytotoxic and cytostatic drugs will be more effective than combination therapy involving only cytotoxic drugs. Thus far, no systematic evaluation of the Goldie and Coldman and Gardner hypotheses have been conducted in the metastatic clinical trial setting. Here I test these hypotheses using the results of over 700 phase II, III and II/III clinical trials. I show that, as predicted by Goldie and Coldman, both overall response rate and overall survival were greater in combination arms. Moreover, median duration of response – the key indicator of the rate of resistance evolution - was also greater in combination vs single agent arms. These results suggest that generally combination chemotherapy is more effective than single agent therapy for advanced solid tumors as predicted by Goldie and Coldman (1979) hypothesis and that, at least in the metastatic setting, the potential disadvantages of combination therapy with respect to accelerated resistance evolution are outweighed by the greater waiting times for resistance mutations to arise. By contrast, although combination cytotoxic and cytostatic therapy is associated with a greater average overall response rate than multi agent cytotoxic therapy, this is not the case for both median duration of response and overall survival. Hence, there is no evidence that, in contrast to the predictions of the Gardner (2002) model, combination cytotoxic and cytostatic therapy decreases the rate of resistance evolution relative to that obtaining under combination cytotoxic therapy.
Thai students' perceptions of studies in Australia
Creators: name: Sharma, Raj
name: Launglaor, Wisanu
name: Thasnapark, Uachit
Publisher: name: Swinburne
Year: 2024

description: Internationalisation of Higher Education is often seen as a great panacea for enhancing socio-economic objectives of developed countries. Indeed often Institutional Research into the phenomenon of Higher Education internationalisation focuses on the perspective of host countries. There is a dearth of internationalisation from the viewpoint of the countries importing University education. The present study aims to at least partially bridge this gap by examining the issue of why Thai students choose to study in Australia. It is hoped that the study may assist South East Asian countries and their Higher Education Institutions obtain a better understanding of why they are net importers of Higher Education.
Note sull’insegnamento del Diritto ecclesiastico nelle Università italiane, oggi
Creators: name: Fabbri, Alberto
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: SOMMARIO: 1. Autonomia e originalità della disciplina - 2. Ambiti attuali della
ricerca – 3. Gli anni ottanta – 4. Gli anni novanta – 5. Gli anni duemila - 6. Una prima conclusione.
description: Stato, Chiese e pluralismo confessionale, 2007: 10 settembre
N-Isocyanates : Versatile Intermediates in Heterocyclic Synthesis
Creators: name: Vincent-Rocan, Jean-François
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: N-isocyanates
Heterocyclic chemistry

description: Nitrogen heterocycles are present in nearly 60% of all small-molecule drugs approved by the US Food and Drug Administration. New innovative methods that streamline the synthesis of such heterocycles are therefore highly desirable. The use of new or underdeveloped reactive intermediates provides an excellent opportunity to develop novel heterocyclic syntheses. For example, nitrogen-substituted isocyanates (N-isocyanates) are a class of rare amphoteric isocyanates with high, but severely underdeveloped synthetic potential. The research efforts presented in this thesis have been directed towards the use of such intermediates for the rapid construction of heterocycles using cascade reactions. Using an in situ generation approach from masked (blocked) isocyanate precursors, we were able to control the homo dimerization of these species and design several cascade reactions forming more than 10 different classes of heterocycles using appropriate nitrogen nucleophiles. Given the importance of the N-N-C=O motif in pharmaceuticals and agrochemicals, N-isocyanates provide the opportunity to synthesize highly desirable cores for different industrial applications. To illustrate the potential of this new tool in heterocyclic chemistry, more than 200 heterocycles were synthesized using this methodology. In Chapter 2, heterocycles incorporating only one atom from the N-isocyanate will be presented. More precisely, the first cascade reaction involving N-isocyanates for the rapid synthesis of saturated heterocycles will be presented. The incorporation of 2 atoms within the ring will then be discussed in Chapter 3 with the synthesis of hydantoins, imidazolones, thiazolines, pyrazoles and phthalazinones. Chapter 4 will focus on the incorporation of every atom in the heterocycle to form other bioactive cores such as azauracils, pyridazinones and azadiketopiperazines. Lastly, Chapter 5 will describe our efforts for the synthesis of acyclic molecules such as semicarbazides and aza-peptides.
Giurisdizione matrimoniale ecclesiastica e poteri autoritativi della magistratura italiana
Creators: name: Boni, Geraldina
Publisher: name: Stato, Chiese e pluralismo confessionale
Year: 2011

description: SOMMARIO: 1. La sentenza n. 22827 del 2004 della Cassazione penale italiana - 2. Il segreto “professionale” del ministro di culto/giudice ecclesiastico - 3. Indipendenza e sovranità della Chiesa nel suo ordine e attività dei tribunali ecclesiastici in materia matrimoniale. La libertà della giurisdizione della Chiesa e la repressione dei reati da parte dello Stato - 4. Il ricorso al giudice italiano in ambito giudiziario matrimoniale canonico. Fisionomia e caratteri del processo canonico di nullità del vincolo e illeciti penali in esso perpetrabili - 5. Quali i possibili effetti delle “interferenze” della giustizia italiana sul processo canonico? - 6. Giurisdizione della Chiesa e giurisdizione dello Stato nell’ottica della reciproca collaborazione tra Stato italiano e Chiesa cattolica per la promozione dell’uomo e il bene del paese.
description: Stato, Chiese e pluralismo confessionale, 2007: 17 settembre
When Anti-Corruption Initiatives Meet the Culture of Wasta: The Case of Public Sector Reforms in Jordan
Creators: name: Al-Saleh, Mohammed
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Public-Sector Organizations
Anti-Corruption Initiative
Organizational Culture Theory
Qualitative Exploratory Methodology
Jordan
Semi-Structured Interviews
Anti-Corruption Strategies
Culture and Leadership
Jordanian public sector

description: Jordan has strived to manage a large-scale anti-corruption initiative for the public sector since 2006. Despite the implementation of laws and bodies mandated to address corruption, public trust of government remains low and the country’s position on international corruption rankings has not improved. This study seeks to investigate how the implementation of a large-scale anti-corruption initiative impacts the organizational culture of the country’s public sector. It proposes that wasta, a unique Arab phenomenon that promotes the values of loyalty, represents the most significant barrier to penetrating what is essentially a normalized culture of corruption in the Government of Jordan. The organizational culture theory model was adopted as the theoretical framework because of its ability to account for differences in culture where promoted values do not necessarily correspond with employee actions. Because literature in this area is rare, a qualitative exploratory methodology was chosen. Based on data saturation, a total of 19 semi-structured interviews were conducted on-site in Jordan with mid-level managers identified using snowball sampling. The results prove the theoretical proposal to be accurate and show that wasta has evolved to the deepest level of organizational culture. The results are sub-divided into two major themes: culture and leadership. The results show that wasta is a deeply held and engrained part of organizational culture and that it is difficult for anti-corruption efforts to change this culture in the Jordanian public sector. The thesis also demonstrate how leadership can be both something negative or something positive in the fight against wasta depending on how it is used.. The findings carry implications for public administration, foreign policy, and society as a whole especially with regard to the development of more effective anti-corruption strategies in Jordan and abroad. The specific contribution to knowledge of this thesis is the examination of how organizational cultural reforms impact public-sector organizations in the Middle Eastern context given the influence of wasta, which is not discussed in the literature but remains important for the field. Future research should consider the views of a wider variety of stakeholders, as well as the impact of wasta on organizational characteristics including performance and delivery of public services.
Philosophy, the environment and population policy
Creators: name: Gare, Arran
Publisher: name: Swinburne
Year: 2024

description: What have and what can philosophers contribute to the debate on population and the environment? I don't think there can be any other discipline where it is more difficult to answer this question. While other disciplines have rival schools of thought, philosophy is the discipline people turn to when they can no longer take for granted a shared framework of assumptions underlying their disagreements. Consequently, it is a discipline riven by diversity of viewpoints, not only on what is the answer to any question, but also on what questions should be asked, how questions should be posed, how they should be answered and how proposed answers should be defended. Philosophers even disagree on what is a question. Perusing the papers written by philosophers on population policy confirms this state of affairs. [Introduction]
Family-centered Care Delivery: Comparing Models of Primary Care Service Delivery in Ontario
Creators: name: Mayo-Bruinsma, Liesha
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: practice organization
primary care
family medicine
family-centered care
health services delivery
secondary data analysis
survey
clustered data
regression analysis
linear mixed regression model
generalised estimating equations

description: Family-centered care (FCC) focuses on considering the family in planning/implementing care and is associated with increased patient satisfaction. Little is known about factors that influence FCC. Using linear mixed modeling and Generalized Estimating Equations to analyze data from a cross-sectional survey of primary care practices in Ontario, this study sought to determine whether models of primary care service delivery differ in their provision of FCC and to identify characteristics of primary care practices associated with FCC. Patient-reported scores of FCC were high, but did not differ significantly among primary care models. After accounting for patient characteristics, practice characteristics were not significantly associated with patient-reported FCC. Provider-reported scores of FCC were significantly higher in Community Health Centres than in Family Health Networks. Higher numbers of nurse practitioners and clinical services on site were associated with higher FCC scores but scores decreased as the number of family physicians at a site increased.
Bridging Decision Applications and Multidimensional Databases
Creators: name: Nargesian, Fatemeh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Business Intelligence
Multidimensional Databases
Schema Mappings
Graphs

description: Data warehouses were envisioned to facilitate analytical reporting and data visualization by providing a model for the flow of data from operational databases to decision support environments. Decision support environments provide a multidimensional conceptual view of the underlying data warehouse, which is usually stored in relational DBMSs. Typically, there is an impedance mismatch between this conceptual view — shared also by all decision support applications accessing the data warehouse — and the physical model of the data stored in relational DBMSs. This thesis presents a mapping compilation algorithm in the context of the Conceptual Integration Model (CIM) [67] framework. In the CIM framework, the relationships between the conceptual model and the physical model are specified by a set of attribute-to-attribute correspondences. The algorithm compiles these correspondences into a set of mappings that associate each construct in the conceptual model with a query on the physical model. Moreover, the homogeneity and summarizability of data in conceptual models is the key to accurate query answering, a necessity in decision making environments. A data-driven approach to refactor relational models into summarizable schemas and instances is proposed as the solution of this issue. We outline the algorithms and challenges in bridging multidimensional conceptual models and the physical model of data warehouses and discuss experimental results.
title: Роль апоптоза и белков протоонкогенов в развитии рака шейки матки
Creators: name: Алексеева, С. Н.
name: Никифоров, П. В.
name: Макарова, Н. Н.
name: Мыреева, С. А.
name: Варламова, В. И.
name: Матвеева, О. А.
Publisher: name: Реноме
Year: 2018

description: Нами проводится исследование по изучению четырех маркеров апоптоза (каспаза-3, каспаза-8, P-53, Цитохром-С) у трех групп пациенток с клинически установленным диагнозом РШМ, СIN3 и практически здоровых женщин. На данном этапе работы завершены сбор биологического материала, обработка анкет и анализ историй болезни. Создана база данных исследуемых групп с использованием программы Microsoft Access.
title: Ирина Сергеевна Лосева, ученый секретарь Архива АН СССР, в предвоенные и военные годы
Creators: name: Прохоренко, Н. С.
Publisher: name: Реноме
Year: 2018

description: И. С. Лосева работала в Архиве всего восемь лет, но оставила яркий след в жизни коллектива. Долгое время была ученым секретарем. Имея большие административные способности, являлась правой рукой директора, а когда во время войны он уехал в эвакуацию, больше года фактически выполняла его обязанности. Тяжелый груз лег на ее плечи: кроме хозяйственных забот, под ее руководством в тяжелейших условиях велась большая работа по комплектованию Архива и описанию документов. Работала в Архиве до сен­тября 1943 г. Дальнейшая судьба ее неизвестна.
Ключевые слова: Архив АН СССР, Великая Отечественная война, блокада Ленинграда, И. С. Лосева, ученый секретарь, спасение документов ученых.
title: Журнал Академии наук «Ежемесячные сочинения, к пользе и увеселению служащие» как интеграционный проект середины XVIII в.
Creators: name: Готовцева, А. Г.
Publisher: name: Реноме
Year: 2018

description: В статье рассматриваются идеология и структура журнала Академии наук «Ежемесячные сочинения, к пользе и увеселению служащие». Внимание уделяется также тому, как повлияла на общую направленность журнала личность редактора — академика Г. Ф. Миллера.

Ключевые слова: Академия наук, журналистика, переводная литература, русская литература, российские географические открытия, научные открытия, русско-европейские научные и литературные связи, Г. Ф. Миллер.
title: Письма Ф. В. Тарановского в Санкт-Петербургском филиале Архива РАН
Creators: name: Михальченко, С. И.
Publisher: name: Реноме
Year: 2018

description: Статья посвящена анализу писем историка и теоретика права Федора Васильевича Тарановского (1875–1936) историку, академику Александру Сергеевичу Лаппо-Данилевскому (1863–1919). Письма хранятся в Санкт-Петербургском филиале Архива Российской Академии наук и относятся к 1911–1917 гг. Их содержание касается двух основных сюжетов — научных планов Тарановского по изучению истории политических учений XVIII века и вопроса об эвакуации Юрьевского университета (где преподавал Тарановский) в годы Первой мировой войны на восток России. Делается вывод о большом значении писем Тарановского Лаппо-Данилевскому как исторического источника.

Ключевые слова: Тарановский Ф. В., Лаппо-Данилевский А. С., переписка ученых, СПбФ АРАН.
title: Возможность использования лучевой терапии при раке вульвы в самостоятельном режиме
Creators: name: Ноговицын, Е. А.
Publisher: name: Реноме
Year: 2018

description: Использование лучевой терапии не уступает комбинированному методу лечения, что позволяет проводить облучение больным, отказавшимся от операции, с выраженной сопутствующей патологией или угрозой тяжелых послеоперационных осложнений.
title: Фармакогенетическое тестирование на определение чувствительности к таргетной терапии моноклональными антителами ингибиторов EGFR Цетуксимаб, Панитумумаб при колоректальном раке
Creators: name: Рудых, З. А.
name: Чертовских, Я. В.
name: Попова, Н. В.
name: Васильева, О. Л.
name: Уткина, М. С.
Publisher: name: Реноме
Year: 2018

description: При раке кишечника анти-EGFR терапия неэффективна при наличии мутаций, т. к. происходит нейтрализация эффекта блокирующих EGFR таргетных препаратов. По литературным данным, частота встречаемости мутации в генах K-Ras при колоректальном раке составляет 40—55%.