cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation
Creators: name: Wu, Yanglin
name: Teng, Yun
name: Zhang, Chenhui
name: Pan, Ying
name: Zhang, Qin
name: Zhu, Xu
name: Liu, Naicheng
name: Su, Xinlin
name: Lin, Jun
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Additional file 1: Table S1. Primer sequences used in qRT-PCR analysis. Figure S1. BHB inhibit NLPR3 inflammasome activated by CoCrMo alloy particles in THP-1 (PMA-induced) macrophages. Figure S2. BHB inhibit inflammasome activation induced cell death by Calcein/PI staining. Figure S3. BHB inhibits pyroptosis-induced LDH release. Figure S4. HDAC activity was involved in the differentiation of osteoclast.
Families of Thue equations associated with a rank one subgroup of the unit group of a number field
Creators: name: Levesque, Claude
name: Waldschmidt, Michel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11D61, 11D41, 11D59

description: Twisting a binary form $F_0(X,Y)\in{\mathbb{Z}}[X,Y]$ of degree $d\ge 3$ by powers $\upsilon^a$ ($a\in{\mathbb{Z}}$) of an algebraic unit $\upsilon$ gives rise to a binary form $F_a(X,Y)\in{\mathbb{Z}}[X,Y]$. More precisely, when $K$ is a number field of degree $d$, $σ_1,σ_2,\dots,σ_d$ the embeddings of $K$ into $\mathbb{C}$, $α$ a nonzero element in $K$, $a_0\in{\mathbb{Z}}$, $a_0>0$ and $$ F_0(X,Y)=a_0\displaystyle\prod_{i=1}^d (X-σ_i(α) Y), $$ then for $a\in{\mathbb{Z}}$ we set $$ F_a(X,Y)=\displaystyle a_0\prod_{i=1}^d (X-σ_i(α\upsilon^a) Y). $$ Given $m\ge 0$, our main result is an effective upper bound for the solutions $(x,y,a)\in{\mathbb{Z}}^3$ of the Diophantine inequalities $$ 0
description: Submitted. 22 pages
Additional file 7: of Metformin, Asian ethnicity and risk of prostate cancer in type 2 diabetes: a systematic review and meta-analysis
Creators: name: Chen, Christopher
name: Eskin, Maxim
name: Eurich, Dean
name: Majumdar, Sumit
name: Johnson, Jeffrey
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Risk of Bias ≤6; Current Metformin Use Vs. No Current Metformin Use in Western- and Asian-Based Cohort Studies. Comparison of metformin use in Western- and Asian-based cohort studies with a Newcastle-Ottawa score ≤ 6. (DOCX 21 kb)
An international expert consensus statement focusing on pre and post hair transplantation care
Creators: name: Vañó-Galván, S.
name: Bisanga, C. N.
name: Bouhanna, P.
name: Farjo, B.
name: Gambino, V.
name: Meyer-González, T.
name: Silyuk, T.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy
subject: Hematology

description: To achieve international expert consensus and give recommendations on best practices in hair transplantation surgery, focusing on pre- and post-transplantation care. A modified Delphi method was used to reach consensus. An international scientific committee developed an 81-statement questionnaire. A panel of 38 experts in hair transplantation from 17 countries across 4 continents assessed the questionnaire. Two consensus rounds were carried out, with 59 out of 81 statements (73%) reaching consensus. Expert recommendations emphasize the correct selection of candidates for hair transplantation and the need for patients to have received adequate medical treatment for alopecia before transplant. Comorbidities should be assessed and considered while planning surgery, and an individualized plan for perioperative care should be drawn up before transplant. Certain medications associated with increased risk of bleeding should be withdrawn before surgery. Specific recommendations for post-transplantation care are given. After transplantation, patients should gradually resume their normal haircare regimen. Close follow-up should be carried out during the first year after transplant. This study presents numerous consensus-based recommendations on general aspects of hair transplantation, including candidate selection, medical therapy prior to transplantation, anesthesia, and resuming haircare after transplantation.
Fast and computationally efficient generative adversarial network algorithm for unmanned aerial vehicle-based network coverage optimization
Creators: name: Ružička, Marek
name: Vološin, Marcel
name: Gazda, Juraj
name: Maksymyuk, Taras
name: Han, Longzhe
name: Dohler, Mischa
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: The challenge of dynamic traffic demand in mobile networks is tackled by moving cells based on unmanned aerial vehicles. Considering the tremendous potential of unmanned aerial vehicles in the future, we propose a new heuristic algorithm for coverage optimization. The proposed algorithm is implemented based on a conditional generative adversarial neural network, with a unique multilayer sum-pooling loss function. To assess the performance of the proposed approach, we compare it with the optimal core-set algorithm and quasi-optimal spiral algorithm. Simulation results show that the proposed approach converges to the quasi-optimal solution with a negligible difference from the global optimum while maintaining a quadratic complexity regardless of the number of users.
description: International Journal of Distributed Sensor Networks. 2022
Additional file 9: Figure S6. of A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence
Creators: name: Eirini-Stavroula Komseli
name: Pateras, Ioannis
name: ThorbjĂ¸Rn Krejsgaard
name: Stawiski, Konrad
name: Rizou, Sophia
name: Polyzos, Alexander
name: Fani-Marlen Roumelioti
name: Chiourea, Maria
name: Mourkioti, Ioanna
name: Paparouna, Eleni
name: Zampetidis, Christos
name: Gumeni, Sentiljana
name: Trougakos, Ioannis
name: Dafni-Eleftheria Pefani
name: OâNeill, Eric
name: Gagos, Sarantis
name: Eliopoulos, Aristides
name: Fendler, Wojciech
name: Dipanjan Chowdhury
name: Jiri Bartek
name: Vassilis Gorgoulis
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Schematic presentation of an R loop. R loops are three-stranded nucleic acid structure. Factors (upper left corner) that promote R loops are indicated as well as the differential cellular effects (bottom) stemming from their formation. (PDF 557Â kb)
Bi Substitution Effects on Superconductivity of Valence-Skip superconductor AgSnSe2
Creators: name: Hijikata, Yudai
name: Nishida, Atsuhiro
name: Nagasaka, Kohei
name: Miura, Osuke
name: Miura, Akira
name: Moriyoshi, Chikako
name: Kuroiwa, Yoshihiro
name: Mizuguchi, Yoshikazu
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We have synthesized AgSn1-xBixSe2 polycrystalline samples to investigate the effect of partial substitution of mixed-valence Sn by Bi3+ to the superconductivity of the valence-skip superconductor AgSnSe2. The Bi-substituted AgSn1-xBixSe2 were obtained up to x = 0.2, but an insulating phase Ag2SnBi2Se5 with a NaCl-type structure showed up above x = 0.3. The superconducting transition temperature increased from 4.5 K (x = 0) to 5.0 K (x = 0.1) by Bi substitution. The enhancement of superconductivity by the suppression of the valence-skip states of Sn suggests that the valence-skip states of Sn are not positively linked to the pairing mechanisms of superconductivity in the AgSnSe2 system.
description: 18 pages, 9 figures and 2 tables including Supplemental Materials
Healing of Defects in Random Antiferromagnetic Spin Chains
Creators: name: Vasseur, Romain
name: Roshani, Arash
name: Haas, Stephan
name: Saleur, Hubert
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the effects of a weakened link in random antiferromagnetic spin chains. We show that healing occurs, and that homogeneity is restored at low energy, in a way that is qualitatively similar to the fate of impurities in clean ferromagnetic spin chains, or in Luttinger liquids with attractive interactions. Healing in the random case occurs even without interactions, and is characteristic of the random singlet phase. Using real space renormalization group and exact diagonalization methods, we characterize this universal healing crossover by studying the entanglement across the weak link. We identify a crossover healing length $L^*$ that separates a regime where the system is cut in half by the weak link from a fixed point where the spin chain is healed. Our results open the way to the study of impurity physics in disordered spin chains.
description: 4.5 + 3 pages. 3 figures
Enhancement of three-mode optomechanical interaction by feedback-controlled light
Creators: name: Kralj, Nenad
name: Rossi, Massimiliano
name: Zippilli, Stefano
name: Natali, Riccardo
name: Borrielli, Antonio
name: Pandraud, Gregory
name: Serra, Enrico
name: Di Giuseppe, Giovanni
name: Vitali, David
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We realise a feedback-controlled optical Fabry-Perot cavity in which the transmitted cavity output is used to modulate the input amplitude fluctuations. The resulting phase-dependent fluctuations of the in-loop optical field, which may be either sub-shot- or super-shot-noise, can be engineered to favorably affect the optomechanical interaction with a nanomechanical membrane placed within the cavity. Here we show that in the super-shot-noise regime ("anti-squashed light") the in-loop field has a strongly reduced effective cavity linewidth, corresponding to an increased optomechanical cooperativity. In this regime feedback improves the simultaneous resolved sideband cooling of two nearly degenerate membrane mechanical modes by one order of magnitude.
description: 16 pages, 11 figures
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity
Creators: name: Peng, Hong
name: Yang, Fang
name: Hu, Qianwen
name: Sun, Jian
name: Peng, Cheng
name: Zhao, Yao
name: Huang, Chuanxin
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: SQSTM1/p62 (sequestosome 1) is a critical macroautophagy/autophagy receptor that promotes the formation and degradation of ubiquitinated aggregates. SQSTM1 can be modified by ubiquitination, and this modification modulates its autophagic activity. However, the molecular mechanisms underpinning its reversible deubiquitination have never been described. Here we report that USP8 (ubiquitin specific peptidase 8) directly interacted with and deubiquitinated SQSTM1. USP8 preferentially removed the lysine 11 (K11)-linked ubiquitin chains from SQSTM1. Moreover, USP8 deubiquitinated SQSTM1 principally at K420 within its ubiquitin-association (UBA) domain. Finally, USP8 inhibited SQSTM1 degradation and autophagic influx in cells with wild-type SQSTM1, but not its mutant with substitution of K420 with an arginine. Taken together, USP8 acts as a negative regulator of autophagy by deubiquitinating SQSTM1 at K420. Abbreviations: BafA1: bafilomycin A1; BAP1: BRCA1 associated protein 1; DUB: deubiquitinating enzyme; ESCRT: endosomal sorting complex required for transport; HTT: huntingtin; K: lysine; KEAP1: kelch like ECH associated protein 1; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MEF: mouse embryonic fibroblast; shRNA: short hairpin RNA; SQSTM1: sequestosome 1; Ub: ubiquitin; UBA: ubiquitin-association; UBE2D2: ubiquitin conjugating enzyme E2 D2; UBE2D3: ubiquitin conjugating enzyme E2 D3; USP: ubiquitin specific peptidase; WT: wild-type
Preheating of the early Universe by radiation from high-mass X-ray binaries
Creators: name: Sazonov, Sergey
name: Khabibullin, Ildar
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Using a reliably measured intrinsic (i.e. corrected for absorption effects) present-day luminosity function of high-mass X-ray binaries (HMXBs) in the 0.25-2 keV energy band per unit star-formation rate, we estimate the preheating of the early Universe by soft X-rays from such systems. We find that X-ray irradiation, mainly executed by ultraluminous and supersoft ultraluminous X-ray sources with luminosity L> 10^39 erg/s, could significantly heat (T>T_cmb, where T_cmb is the temperature of the cosmic microwave background) the intergalactic medium by z~10 if the specific X-ray emissivity of the young stellar population in the early Universe was an order of magnitude higher than at the present epoch (which is possible due to the low metallicity of the first galaxies) and the soft X-ray emission from HMXBs did not suffer strong absorption within their galaxies. This makes it possible to observe the 21 cm line of neutral hydrogen in emission from redshifts z<10.
description: 9 pages, 4 figures, accepted for publication in Astronomy Letters
Distribution and dispersal of legacy sediment and contamination from historical gold mining at Hill End, New South Wales, Australia
Creators: name: Nagle, Nathan
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The gold rushes in the 19th century impacted landscapes throughout the world through vegetation clearance, disturbance of soil and sediment and the release of metals (e.g. mercury and arsenic) into the environment. Legacy sediment episodically produced from anthropogenic activities such as gold mining is now stored in modern landscapes and can contain high concentrations of metals. In Australia, the little research into the environmental impacts of historical gold mining has generally focused on metal contamination and there has been limited research into long-term geomorphological changes in landscapes associated with gold mining processes such as the impact of large scale legacy sediment production. This study explored the long-term environmental impacts of historical gold mining at Hill End, New South Wales, Australia, by investigating the dispersal of legacy sediment as well as spatial patterns and temporal trends of mercury, arsenic, lead, copper and zinc contamination. Soil and sediment metal contamination was analysed using X-ray fluorescence (XRF) and a direct mercury analyser. Optically stimulated luminescence (OSL) and excess 210Pb were used to constrain temporal patterns of contamination and sedimentation. Hill End has high hillslope-channel and longitudinal connectivity and there are few places where legacysediment storage occurs within the catchment. In the uplands of Hill End, legacy sediment is stored in finely laminated sequences in tailings dams. There was no sediment stored in the steep gorges of Hill End and sediment was stored with cobbles and gravel in occasional midchannel and bank attached bars in the lower reaches of the system. The majority of samples contained little to no metal enrichment and high levels of metal contamination were mainly restricted to artificial depocentres such as tailings dams and in spoil adjacent to stamper batteries and cyanide tanks. Chemostratigraphy and sediment dating in Chappell’s Dam revealed that metal contamination peaked during the height of gold mining (c. 1871-1880). It declined shortly after the cessation of ore processing in the adjacent stamper battery, coinciding with the decline of gold mining in the region. Peak metal concentrations of mercury (44.58 mg kg⁻¹) and arsenic (221.0 mg kg⁻¹) found in Chappell’s Dam are well above ANZECC sediment quality guidelines and could pose a risk to local aquatic ecosystems. Understanding the fate of legacy sediment and metal contaminated sediment in a highly connected system such as Hill End will shed light on the larger scale impacts of historical gold mining in Australia and can be used to inform management strategies for derelict and active mines.
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity
Creators: name: Peng, Hong
name: Yang, Fang
name: Hu, Qianwen
name: Sun, Jian
name: Peng, Cheng
name: Zhao, Yao
name: Huang, Chuanxin
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Virology

description: SQSTM1/p62 (sequestosome 1) is a critical macroautophagy/autophagy receptor that promotes the formation and degradation of ubiquitinated aggregates. SQSTM1 can be modified by ubiquitination, and this modification modulates its autophagic activity. However, the molecular mechanisms underpinning its reversible deubiquitination have never been described. Here we report that USP8 (ubiquitin specific peptidase 8) directly interacted with and deubiquitinated SQSTM1. USP8 preferentially removed the lysine 11 (K11)-linked ubiquitin chains from SQSTM1. Moreover, USP8 deubiquitinated SQSTM1 principally at K420 within its ubiquitin-association (UBA) domain. Finally, USP8 inhibited SQSTM1 degradation and autophagic influx in cells with wild-type SQSTM1, but not its mutant with substitution of K420 with an arginine. Taken together, USP8 acts as a negative regulator of autophagy by deubiquitinating SQSTM1 at K420.
Nanoscale Magnetic Compasses
Creators: name: Shiozawa, Hidetsugu
name: Zhang, Desai
name: Eisterer, Michael
name: Ayala, Paola
name: Pichler, Thomas
name: McCartney, Martha R.
name: Smith, David J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We have synthesized nanoscale magnetic compasses with high yield. These ferromagnetic iron carbide nano-particles, which are encapsulated in a pair of parallel carbon needles, change their direction in response to an external magnetic field. Electron holography reveals magnetic fields confined to the vicinity of the bicone-shaped particles, which are composed of few ferromagnetic domains. Aligned magnetically and encapsulated in an acrylate polymer matrix, these nanocompasses exhibit anisotropic bulk magnetic permeability with an easy axis normal to the needle direction, that can be understood as a result of the anisotropic demagnetizing field of a nonspherical single-domain particle. This novel material with orthogonal magnetic and structural axes could be highly useful as magnetic components in electromagnetic wave absorbent materials and magnetorheological fluids.
description: 13 pages, 5 figures
Ixekizumab is effective in the long-term management in moderate-to-severe plaque psoriasis: results from an Italian retrospective cohort study (the LOTIXE study)
Creators: name: Chiricozzi, Andrea
name: Megna, Matteo
name: Giunta, Alessandro
name: Carrera, Carlo Giovanni
name: Dapavo, Paolo
name: Balato, Anna
name: Malagoli, Piergiorgio
name: Mazzoccoli, Stella
name: Parodi, Aurora
name: Sabatino, Silvia
name: Buzzoni, Carlotta
name: Huang, Chu-Han
name: Narcisi, Alessandra
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Ixekizumab is a high-affinity monoclonal antibody that selectively targets interleukin (IL)-17A approved for the treatment of moderate-to-severe plaque psoriasis. The objective of this study was to describe the real-world long-term effectiveness of ixekizumab in patients with plaque psoriasis in Italy. A retrospective study was conducted in patients affected by moderate-to-severe plaque psoriasis who were continuously treated with ixekizumab for at least 12 months. Patient data was obtained at 4-weeks, 12-weeks and 6-, 12-, 18- and 24-months after baseline (June 2017 and September 2019) from 10 sites. Results were analyzed by complete case approach, with sensitivity analysis performed to evaluate the impact of missing data. A total of 198 patients were enrolled in the study. At Month 24, 94.3% of patients achieved PASI75 response, while 85.1 and 71.8% achieved PASI90 and PASI100, respectively; and 91.1% of the patients achieved absolute PASI score ≤2. Patients experienced psoriasis improvement at 4 weeks after starting treatment, and improvement was maintained with continued ixekizumab use. The quality of life of patients also improved significantly starting at Week 12, with sustained effect in the long term. This 24-month observational cohort study confirmed that ixekizumab is effective in the long-term management of patients with moderate-to-severe plaque psoriasis.
The best defense is a good defense: adapting negotiation methods for tackling pressure over software project estimates
Creators: name: Matsubara, Patricia G. F.
name: Steinmacher, Igor
name: Gadelha, Bruno
name: Conte, Tayana
Publisher: name: arXiv
Year: 2022
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences
subject: D.2.9

description: Software estimation is critical for a software project's success and a challenging activity. We argue that estimation problems are not restricted to the generation of estimates but also their use for commitment establishment: project stakeholders pressure estimators to change their estimates or to accept unrealistic commitments to attain business goals. In this study, we employed a Design Science Research (DSR) methodology to design an artifact based on negotiation methods, to empower software estimators in defending their estimates and searching for alternatives to unrealistic commitments when facing pressure. The artifact is a concrete step towards disseminating the soft skill of negotiation among practitioners. We present the preliminary results from a focus group that showed that practitioners from the software industry could use the artifact in a concrete scenario when estimating and establishing commitments about a software project. Our future steps include improving the artifact with the suggestions from focus group participants and evaluating it empirically in real software projects in the industry.
description: 5 pages, 1 figure, 1 table
Financial Conditions in the U.S. Agricultural Sector: Historical Comparisons
Creators: name: Key, Nigel
name: Burns, Christopher
name: Lyons, Greg
name: Key, Nigel
name: Burns, Christopher
name: Lyons, Greg
Publisher: name: Unknown
Year: 2019
Subjects: subject: Agricultural and Food Policy
subject: Agricultural Finance
subject: Farm Management
subject: Financial Economics
subject: Land Economics/Use
subject: Production Economics
subject: Farm financial performance
subject: farm income
subject: debt
subject: liquidity
subject: loan repayment capacity
subject: working capital
subject: solvency
subject: debt-to-asset ratio
subject: agricultural lending
subject: default rate
subject: financial stress

description: Recent economic conditions and the financial health of the U.S. farm sector have raised concerns among farm policy stakeholders. After peaking around 2012, farm sector income declined while farm debt continued to rise. Farm real estate stopped rapidly appreciating in value, and land prices declined in some regions. Between 2016 and early 2019, interest rates rose—increasing the cost of borrowing for some farmers. Lower commodity prices in the near future would make it more difficult for some farmers to meet their loan obligations and pay for production expenses. Farmers who made substantial investments in machinery or land when commodity prices and farm incomes were high could face elevated risks of financial insolvency. This study compares recent sectoral and farm-level measures of financial performance relative to historic levels to better understand the severity of the current downturn in the agricultural economy. Using data from USDA’s Agricultural Resource Management Survey, researchers disaggregate farm-level measures of financial health across farm types to identify the types of farms that are under the greatest financial stress. To provide additional perspective on the financial health of the sector, the study uses data from agricultural lenders to compare current agricultural loan delinquencies to levels in the recent past. Finally, model results on the effects of a hypothetical decline in gross farm income are used to evaluate the types of farm operations that would be most vulnerable to a further downturn in the agricultural economy.
Challenges in the convergence of international financial reporting standards (IFRS): a comparative study of Indonesia and Australia
Creators: name: Maradona, Agus Fredy
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The increasing popularity of International Financial Reporting Standards (IFRS) over the last few years has led to a growing number of IFRS adopters around the world. As of 2016, more than 130 countries have adopted the IFRS, with many other countries stating a commitment to support the global accounting convergence initiated by the International Accounting Standards Board. The worldwide adoption of IFRS is believed to result in a greater cross - national comparability of financial information which, in turn, will benefit the global economy. This thesis aims to undertake a comprehensive examination of the conceptual and practical issues associated with the adoption of IFRS in both developed and developing economies. Specifically, this thesis seeks to answer the question of whether convergence in accounting standards will necessarily lead to comparability of financial reporting practices, and to propose possible ways to improve consistencies in the interpretation and application of the IFRS within and across countries. To address this issue, the thesis undertakes four research projects with the following objectives: (1) to critically analyse the process of convergence in a developing country and to identify the critical issues in that process; (2) to examine whether cultural and personal factors cause differences in the judgements made by professional accountants across countries when interpreting and applying the IFRS; (3) to examine the extent and the cause of differences in the ethical decisions between professional accountant s across countries when applying the IFRS; and (4) to examine the perceptions of professional accountants towards the skills and competencies that are essential for applying the IFRS. The findings of this thesis suggest that there are intense challenges f acing the adoption of IFRS in different countries, which hampers the comparability of financial reporting practices under the standards. In particular, this study demonstrates that the measurement and recognition criteria contained in the IFRS are not interpreted and applied in a consistent manner across and within countries due to differences in cultural, organisational, personal, and ethical characteristics. The findings of this thesis also show that even when the IFRS are adopted, accounting practitioner s might not have adequately developed certain skills that are crucial for the consistent application of the standards. Overall, the results of this thesis raise questions regarding the assumption that the global adoption of IFRS will necessarily lead to co mparable financial statements across countries.
title: ADCO, Cartulaire de Fontenay, second fragment (XIIIe siècle), Cart. 201 (15 H 9), folios 47-142, f. 011v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire de Fontenay, second fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), folios 47-142. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Fontenay, second fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), folios 47-142, f. 011v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Fontenay
description: Provenance: http://www.wikidata.org/entity/Q464918
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb119679755
description: Provenance: https://www.geonames.org/7874015
description: Provenance: http://www.idref.fr/027691802/id
Additional file 2 of Analysis of the genetic contribution to thoracic aortic aneurysm or dissection in a prospective cohort of patients with familial and sporadic cases in East China
Creators: name: Duan, Yanyu
name: Xiong, Jianxian
name: Lai, Zhenghong
name: Zhong, Yiming
name: Tian, Chengnan
name: Du, Zhiming
name: Luo, Zhifang
name: Yu, Junjian
name: Li, Wentong
name: Xu, Weichang
name: Wang, Yabing
name: Ding, Ting
name: Zhong, Xuehong
name: Pan, Mengmeng
name: Qiu, Yu
name: Lan, Xuemei
name: Chen, Taihua
name: Li, Peijun
name: Liu, Kang
name: Gao, Meng
name: Hu, Yanqiu
name: Liu, Ziyou
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 2
Data Management Plan
Creators: name: Osborne, Bruce
Publisher: name: Osborne Bruce, University College Dublin (UCD)
Year: 2024
Subjects: Farming

description: Data Management Plan for the Open Farm Data -Community's curated sustainable farming-related open datasets, models, software, articles, reports, and other resources with a Creative Commons Attribution 4.0 International license. It is a living document, which will guide research projects and get updated when existing and new partners recognise such needs. The work has been funded as part of the ERA-Net scheme, which supports the bottom-up coordination of national and regional programmes in the European Union, in this case through the joint call of the co-fund ERA-Nets SusCrop (Grant N° 771134), FACCE ERA-GAS (Grant N° 696356), ICT-AGRI-FOOD (Grant N° 862665) and SusAn (Grant N° 696231).
Magnetism in f electron superlattices
Creators: name: Peters, Robert
name: Tada, Yasuhiro
name: Kawakami, Norio
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We analyze antiferromagnetism in $f$ electron superlattices. We show that the competition between the Kondo effect and the RKKY interaction in $f$ electron materials is modified by the superlattice structure. Thus, the quantum critical point which separates the magnetic phase and the Fermi liquid phase depends on the structure of the $f$ electron superlattice. The competition between the Kondo effect and the RKKY interaction is also reflected in the magnetic interlayer coupling between different $f$ electron layers. We demonstrate that in the case of weak Kondo effect the magnetic interlayer coupling behaves similar to other magnetic heterostructures without Kondo effect. However, close to the quantum phase transition, the dependence of the interlayer coupling on the distance between the $f$ electron layers is modified by the Kondo effect. Another remarkable effect, which is characteristic for $f$ electron superlattice, is that the magnetic interlayer coupling does vanish stepwise depending on the distance between different $f$ electron layers. As a consequence, the quantum critical point depends also stepwise on this distance.
Additional file 6: of Metformin, Asian ethnicity and risk of prostate cancer in type 2 diabetes: a systematic review and meta-analysis
Creators: name: Chen, Christopher
name: Eskin, Maxim
name: Eurich, Dean
name: Majumdar, Sumit
name: Johnson, Jeffrey
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Current Metformin Use Vs. No Current Metformin Use in Asian-Based Case-Control Studies. Comparison of metformin use in Asian-based case-control studies (DOCX 16Â kb)
Steps towards implementation of protocolized dose reduction of adalimumab, etanercept and ustekinumab for psoriasis in daily practice
Creators: name: van der Schoot, L.S.
name: Janssen, J.J.
name: Bastiaens, M.T.
name: de Boer-Brand, A.
name: Christiaansen-Smit, C.
name: Enomoto, D.N.H.
name: Hovingh, R.
name: Tupker, R.A.
name: Seyger, M.M.B.
name: Verhoef, L.M.
name: van den Reek, J.M.P.A.
name: de Jong, E.M.G.J.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Dose reduction (DR) of adalimumab, etanercept and ustekinumab has proven to be (cost-)effective in psoriasis patients with low disease activity. Further implementation is needed to establish application of DR for eligible patients. To evaluate the implementation of protocolized biologic DR in daily practice. A pilot implementation study was performed in 3 hospitals during 6 months. By combining education and protocol development, involved healthcare providers (HCPs) were directed toward the adoption of protocolized DR. DR of adalimumab, etanercept, and ustekinumab was achieved by stepwise injection interval prolongation. Implementation outcomes (fidelity, feasibility) were assessed. Factors for optimizing implementation were explored in interviews with HCPs. Uptake was measured in patients by chart review. The implementation strategy was executed as planned. Implementation fidelity was less than 100% as not all provided tools were used across study sites. HCPs indicated the feasibility of implementing protocolized DR, although time investment was needed. Identified additional factors for successful implementation included support for patients, uptake of DR into guidelines, and supportive electronic health record systems. During the 6 months intervention period, 52 patients were eligible for DR of whom 26 (50%) started DR. The proposed DR protocol was followed in 22/26 patients (85%) on DR. Additional staff for support, extra time during consultations, education on DR for HCPs and patients, and effective tools such as a feasible protocol can lead to more patients on biologic DR.
Additional file 2 of Construction and validation of immune-related LncRNAs classifier to predict prognosis and immunotherapy response in laryngeal squamous cell carcinoma
Creators: name: Wang, Xiaofeng
name: Pan, Ya
name: Ou, Yangpeng
name: Duan, Tingting
name: Zou, Yuxia
name: Zhou, Xuejun
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 2. Supplementary material 1.
title: ADCO, Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Cart. 143 (7 H 7), 153 fol, f. 0125r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Petot, Frédéric
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0125r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0125r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Molesme
description: Provenance: http://www.wikidata.org/entity/Q334044
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb137389344
Models of modified $F(R,T)$ and cuscuton braneworld
Creators: name: Bazeia, D.
name: Lobão, A. S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This work deals with braneworld models in the presence of scalar fields in a five-dimensional warped geometry with a single extra dimension of infinite extent. We consider generalized models in the presence of the Ricci scalar, the trace of the stress-energy tensor and the cuscuton contribution. The models describe novel braneworld scenarios and the investigations consider distinct possibilities, from which we show how the brane may change to become thinner, although keeping gravitational stability and the gravity zero mode under strict control. Moreover, we did not identify any split behavior in the warp factor in the presence of the cuscuton and the trace of the stress-energy tensor.
description: 7 pages, 11 figures
Additional file 8: Figure S5. of A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence
Creators: name: Eirini-Stavroula Komseli
name: Pateras, Ioannis
name: Krejsgaard, Thorbjørn
name: Stawiski, Konrad
name: Rizou, Sophia
name: Polyzos, Alexander
name: Fani-Marlen Roumelioti
name: Chiourea, Maria
name: Mourkioti, Ioanna
name: Paparouna, Eleni
name: Zampetidis, Christos
name: Gumeni, Sentiljana
name: Trougakos, Ioannis
name: Dafni-Eleftheria Pefani
name: O’Neill, Eric
name: Gagos, Sarantis
name: Eliopoulos, Aristides
name: Fendler, Wojciech
name: Dipanjan Chowdhury
name: Jiri Bartek
name: Vassilis Gorgoulis
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Comparative Inverted DAPI Banding karyotyping of 20 metaphase spreads from the OFF (on the left) and the “escaped” (on the right) cells. Arrows indicate random chromosome rearrangements (chromosomal instability). The rates of random structural chromosome rearrangements were found 3.5-times more pronounced in the "escaped" cells. (PDF 554 kb)
Additional file 5: of Metformin, Asian ethnicity and risk of prostate cancer in type 2 diabetes: a systematic review and meta-analysis
Creators: name: Chen, Christopher
name: Eskin, Maxim
name: Eurich, Dean
name: Majumdar, Sumit
name: Johnson, Jeffrey
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Current Metformin Use Vs. No Current Metformin Use in Western-Based Case-Control Studies. Comparison of metformin use in Western-based case-control studies (DOCX 22Â kb)
title: Pince de forgeron (Inv. 2003.7.6972.2) – Oppidum de Bibracte
Creators: name: Bibracte
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: forgeron

description: De nombreux outils fabriqués par les forgerons gaulois font encore partie de notre boîte à outils aujourd hui. Cela signifie-t-il que la période celtique a été à l origine d importantes innovations technologiques ? Ce n est pas si certain. Le principal mérite de ces artisans a été de rationaliser l usage de savoir-faire et d outils déjà connus. Les métiers se sont différenciés  et chacun a disposé d un outillage spécifique. Les forgerons ne font pas exception à la règle : marteaux  pinces et enclumes font partie des outils usuels des métallurgistes.
Additional file 7: Figure S4. of A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence
Creators: name: Eirini-Stavroula Komseli
name: Pateras, Ioannis
name: Krejsgaard, Thorbjørn
name: Stawiski, Konrad
name: Rizou, Sophia
name: Polyzos, Alexander
name: Fani-Marlen Roumelioti
name: Chiourea, Maria
name: Mourkioti, Ioanna
name: Paparouna, Eleni
name: Zampetidis, Christos
name: Gumeni, Sentiljana
name: Trougakos, Ioannis
name: Dafni-Eleftheria Pefani
name: O’Neill, Eric
name: Gagos, Sarantis
name: Eliopoulos, Aristides
name: Fendler, Wojciech
name: Dipanjan Chowdhury
name: Jiri Bartek
name: Vassilis Gorgoulis
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Morphological features of HBEC CDC6 Tet-ON. a) Inverted-phase contrast photographs (Scale bar: 25 μm) and bi) GL13 staining showed the dominance of senescent, flattened and multinucleated cells upon 6-day CDC6-induction; features that were substituted by a spindle morphology in the “escaped” cells. Traces of GL13 staining in the early "escaped" cells (indicated by arrows) prove their origin from senescent cells. bii) Sa-β-Gal activity correlates with GL13 staining. (Scale bar: 15 μm). (PDF 689 kb)
Additional file 4: of Metformin, Asian ethnicity and risk of prostate cancer in type 2 diabetes: a systematic review and meta-analysis
Creators: name: Chen, Christopher
name: Eskin, Maxim
name: Eurich, Dean
name: Majumdar, Sumit
name: Johnson, Jeffrey
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Current Metformin Use Vs. No Current Metformin Use in Western- and Asian-Based Case-Control Studies. Comparison of metformin use in Western- and Asian-based case-control studies. (DOCX 22Â kb)
title: Pince de forgeron (Inv. 2003.7.6972.2)
Creators: name: Tisserand, Nicolas
name: Chevrier, Sébastien
name: Paris, Pascal
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: forgeron
subject: Artefact
subject: ACQUISITION

description: Modèle 3D
Additional file 6: Figure S3. of A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence
Creators: name: Eirini-Stavroula Komseli
name: Pateras, Ioannis
name: ThorbjĂ¸Rn Krejsgaard
name: Stawiski, Konrad
name: Rizou, Sophia
name: Polyzos, Alexander
name: Fani-Marlen Roumelioti
name: Chiourea, Maria
name: Mourkioti, Ioanna
name: Paparouna, Eleni
name: Zampetidis, Christos
name: Gumeni, Sentiljana
name: Trougakos, Ioannis
name: Dafni-Eleftheria Pefani
name: OâNeill, Eric
name: Gagos, Sarantis
name: Eliopoulos, Aristides
name: Fendler, Wojciech
name: Dipanjan Chowdhury
name: Jiri Bartek
name: Vassilis Gorgoulis
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer

description: CDC6 binding onto the promoters of CDH1 and INK4/ARF loci of HBEC CDC6 Tet-ON system leading to transcriptional down-regulation. a) Chromatin immunoprecipitation (ChIP) assay showed that MYC-tagged CDC6 is bound on both the regulatory domain (RD) of INK4/ARF locus and the Epal element of CDH1, when induced. b) RD of INK4 locus is enriched in DNA extracted from both anti-CDC6 (endogenous and exogenous) and anti-MYC-tag (exogenous) IPs in HBEC CDC6 over-expressing cells normalized to input and INK4b intron (RNA Pol II-IP serves as a negative control confirming transcriptional down-regulation). c) ChIP samples run on a SDS-PAGE gel revealed that CDC6 is accessible and immunoprecipitated by both CDC6 and MYC-tag antibodies with the protocol followed. (PDF 146Â kb)
Additional file 3: of Metformin, Asian ethnicity and risk of prostate cancer in type 2 diabetes: a systematic review and meta-analysis
Creators: name: Chen, Christopher
name: Eskin, Maxim
name: Eurich, Dean
name: Majumdar, Sumit
name: Johnson, Jeffrey
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Current Metformin Use Vs. No Current Metformin Use in Asian-Based Cohort Studies. Comparison of metformin use in Asian-based cohort studies. (DOCX 17Â kb)