cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Isolation, structure determination and total synthesis of potential cancer chemotherapeutic agents from natural sources
Creators: name: Britton, Robert A.
Publisher: name: University of British Columbia
Year: 2009

description: The ultimate goal in the chemotherapeutic treatment of cancer is the development of drugs that are highly effective against tumor cells and have little or no effect on healthy cells. Key to this pursuit is the identification of differences that exist between the life cycle of normal and cancerous cells. Thus, the discovery of new small molecule inhibitors of enzymes that regulate cellular growth and division should provide a better understanding of these biological processes and perhaps lead to more selective cancer treatments. Mitosis, or cell division, is disrupted by antimitotic agents, which correspondingly have become the most promising chemotherapeutics in cancer treatment. Recently, the Caribbean soft coral Erythropodium caribaeorum was shown to be a good source of eleutherobin, a potent antimitotic agent. Having procured eleutherobin from this source, synthetic manipulations of the natural material provided a series of eleuthoside congeners, which were assayed for antimitotic activity. A remarkable relationship between the Δ[sup 2’,3’] olefin and eleuthoside biological activity was highlighted by these studies. The G2 checkpoint is one of a series of checkpoints that temporarily halt cell cycle progression in order to allow for repair of damaged DNA. It has been demonstrated in vitro that the inhibition of this checkpoint, in combination with a DNA damaging agent, selectively potentiates the killing of cancer cells. Extracts of the Brazilian ascidian Didemnum granulatum demonstrated G2 checkpoint inhibition activity. Fractionation of these extracts resulted in the isolation of isogranulatimide. In order to unambiguously confirm the structural assignment of this substance, generate sufficient material for biological testing and investigate the effect of structure on its biological activity, an efficient synthesis of isogranulatimide and several congeners was developed. Concurrently, two new analogues of okadaic acid, a potent protein phosphatase inhibitor, have been isolated from the sponge Merriamum oxeato, collected in Jervis Inlet, British Columbia. These substances displayed pronounced G2 checkpoint inhibition activity and represent the first examples of diarrhetic shellfish poisons (DSP) in the Northeastern Pacific Ocean. A total synthesis of 13-methoxy-15-oxozoapatlin, a G2 checkpoint inhibitor and antimitotic agent, has also been completed. Employing a linear sequence of 22 synthetic transformations, a renewable source of this structurally complex pentacyclic diterpene has been realized. The completion of this synthesis relied on the development of new synthetic methods useful in the construction of bicyclo[3.2.1 ]octanes.
Scalar sextet in the 331 model with right-handed neutrinos
Creators: name: Ky, Nguyen Anh
name: Van, Nguyen Thi Hong
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A Higgs sextet is introduced in order to generate Dirac and Majorana neutrino masses in the 331 model with right-handed neutrinos. As will be seen, the present sextet introduction leads to a rich neutrino mass structure. The smallness of neutrino masses can be achieved via, for example, a seesaw limit. The fact that the masses of the charged leptons are not effected by their new Yukawa couplings to the sextet is convenient for generating small neutrino masses.
description: RevTeX4, 5 pages, no figure. To appear in Phys. Rev. D. Misprints removed (v.2)
MARKETING INFORMATION AS A CONSTRAINT TO LOCALLY GROWN PRODUCE: EVIDENCE FROM OHIO
Creators: name: Jones, Eugene
name: Batte, Marvin T.
name: Schnitkey, Gary D.
name: Jones, Eugene
name: Batte, Marvin T.
name: Schnitkey, Gary D.
Publisher: name: Unknown
Year: 1990
Subjects: subject: Marketing
subject: FOS: Economics and business

description: A random sample of 200 Ohio fruit producers were surveyed in January 1988, regarding their use of information for decision making. Survey responses were used to determine if improved marketing information increases the likelihood of Ohio fruit producers gaining a larger share of Ohio's produce market. Results from the production adequacy equations show that larger producers and those marketing a predominate share of their fruit through wholesalers and retailers are the ones most likely to agree that their fruit production is limited by insufficient marketing information. These results suggest an opportunity for Ohio to gain a larger share of the produce market.
เก็บตกใบเซียมซีที่มอดินแดง
Creators: name: ลักษณา โตวิวัฒน์
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2002
Subjects: -

description: วรรณวิทัศน์, 2, พฤศจิกายน, 159-166
The statistics of Sco X-1 kHZ QPOs
Creators: name: Bulik, Tomasz
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Recently an additional technique was applied to investigate the properties of kHz QPOS, i.e. the analysis of the distribution of frequency ratios or frequencies themselves. I review the results of such work on the data from ScoX-1: Abramowicz et al. (2003), which was later criticized by Belloni et al.(2005). I conclude that the findings of the latter paper are consistent with results presented earlier: kHz QPOs cluster around the value corresponding to the frequency ratio of 2/3. I also discuss the random walk model of kHz QPOs and possible future observations needed to verify it.
description: Astronomische Nachrichten, in press
Toward the Detection of Transiting Hot Earths and Hot Neptunes in Open Clusters
Creators: name: Pepper, Joshua
name: Gaudi, B. Scott
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Radial velocity searches for extrasolar planets have recently detected several very low mass (7-20M_Earth) planets in close orbits with periods <10 days. We consider the prospects for detecting the analogs of these planets in Galactic open clusters via transits. We outline the requirements for constructing a transit survey that would allow one to probe such ``Hot Earths'' and ``Hot Neptunes.'' Specifically, we present a simple criterion for detection that defines the minimum aperture required to detect planets of a given radius in a cluster at a given distance. Adopting photometric precisions that have been demonstrated in state-of-the-art variability surveys, we then predict the number of planets one could potentially detect with ambitious transit surveys toward several open clusters. Dedicated surveys lasting more than 20 nights with Pan-STARRS toward the Hyades and Praesepe could detect a handful of Hot Earths, if the majority of stars host such planets. Similar surveys with larger aperture telescopes (e.g. CFHT, MMT), toward M67, M35, M50, and M37 could detect Hot Neptunes, provided that their frequency is >1%. The majority of planets will be detected around M dwarfs; detecting Hot Neptunes around such primaries requires photometric precisions of ~1%, whereas Hot Earths require \~0.1%. We discuss potential hurdles in detecting and confirming small planets in ground-based surveys, including correlated noise, false positives, and intrinsic stellar variability.
description: 7 pages, 3 figures, accepted to Acta Astronomica
Limits to Rest-Frame Ultraviolet Emission From Far-Infrared-Luminous z~6 Quasar Hosts
Creators: name: Marshall, Madeline A.
name: Mechtley, Mira
name: Windhorst, Rogier A.
name: Cohen, Seth H.
name: Jansen, Rolf A.
name: Jiang, Linhua
name: Jones, Victoria R.
name: Wyithe, J. Stuart B.
name: Fan, Xiaohui
name: Hathi, Nimish P.
name: Jahnke, Knud
name: Keel, William C.
name: Koekemoer, Anton M.
name: Marian, Victor
name: Ren, Keven
name: Robinson, Jenna
name: Röttgering, Huub J. A.
name: Ryan, Russell E.
name: Scannapieco, Evan
name: Schneider, Donald P.
name: Schneider, Glenn
name: Smith, Brent M.
name: Yan, Haojing
Publisher: name: arXiv
Year: 2020
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report on a Hubble Space Telescope search for rest-frame ultraviolet emission from the host galaxies of five far-infrared-luminous $z\simeq{}6$ quasars and the $z=5.85$ hot-dust free quasar SDSS J0005-0006. We perform 2D surface brightness modeling for each quasar using a Markov-Chain Monte-Carlo estimator, to simultaneously fit and subtract the quasar point source in order to constrain the underlying host galaxy emission. We measure upper limits for the quasar host galaxies of $m_J>22.7$ mag and $m_H>22.4$ mag, corresponding to stellar masses of $M_\ast<2\times10^{11}M_\odot$. These stellar mass limits are consistent with the local $M_{\textrm{BH}}$-$M_\ast$ relation. Our flux limits are consistent with those predicted for the UV stellar populations of $z\simeq6$ host galaxies, but likely in the presence of significant dust ($\langle A_{\mathrm{UV}}\rangle\simeq 2.6$ mag). We also detect a total of up to 9 potential $z\simeq6$ quasar companion galaxies surrounding five of the six quasars, separated from the quasars by 1.4''-3.2'', or 8.4-19.4 kpc, which may be interacting with the quasar hosts. These nearby companion galaxies have UV absolute magnitudes of -22.1 to -19.9 mag, and UV spectral slopes $β$ of -2.0 to -0.2, consistent with luminous star-forming galaxies at $z\simeq6$. These results suggest that the quasars are in dense environments typical of luminous $z\simeq6$ galaxies. However, we cannot rule out the possibility that some of these companions are foreground interlopers. Infrared observations with the James Webb Space Telescope will be needed to detect the $z\simeq6$ quasar host galaxies and better constrain their stellar mass and dust content.
description: 22 pages, 13 figures. Accepted for publication in ApJ
Richtigstellungen über Agapius von Manbiǧ und sein historisches Werk
Creators: name: Breydy, Michel
Publisher: name: Oriens christianus : Hefte für die Kunde des christlichen Orients
Year: 2024

description: Oriens christianus : Hefte für die Kunde des christlichen Orients, Bd. 73 (1989): Oriens christianus, Band 73
Towards the NNLL precision in $\bar B \to X_s γ$
Creators: name: Asatrian, H.
name: Hovhannisyan, A.
name: Poghosyan, V.
name: Greub, C.
name: Hurth, T.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The present NLL prediction for the decay rate of the rare inclusive process $\bar B \to X_s γ$ has a large uncertainty due to the charm mass renormalization scheme ambiguity. We estimate that this uncertainty will be reduced by a factor of 2 at the NNLL level. This is a strong motivation for the on-going NNLL calculation, which will thus significantly increase the sensitivity of the observable $\bar B \to X_s γ$ to possible new degrees of freedom beyond the SM. We also give a brief status report of the NNLL calculation.
description: 5 pages, 2 figures, contribution to the proceedings of EPS-HEP 2005
Additional file 1 of Assessing what matters most to patients with or at risk for Alzheimer’s and care partners: a qualitative study evaluating symptoms, impacts, and outcomes
Creators: name: DiBenedetti, Dana B.
name: Slota, Christina
name: Wronski, Samantha L.
name: Vradenburg, George
name: Comer, Meryl
name: Callahan, Leigh F.
name: Winfield, John
name: Rubino, Ivana
name: Krasa, Holly B.
name: Hartry, Ann
name: Wieberg, Dan
name: Kremer, Ian N.
name: Lappin, Debra
name: Martin, Allison D.
name: Frangiosa, Terry
name: Biggar, Virginia
name: Hauber, Brett
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Supplemental Appendix
Reconstructing the base field from imaginary multiplicative chaos
Creators: name: Aru, Juhan
name: Junnila, Janne
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 60G15, 60G20, 60G57, 60G60, 82B21

description: We show that the imaginary multiplicative chaos $\exp(iβΓ)$ determines the gradient of the underlying field $Γ$ for all log-correlated Gaussian fields with covariance of the form $-\log |x-y| + g(x,y)$ with mild regularity conditions on $g$, for all $d \geq 2$ and for all $β\in (0,\sqrt{d})$. In particular, we show that the 2D continuum zero boundary Gaussian free field is measurable w.r.t. its imaginary chaos.
description: Most notable changes in the title, unfortunately still no figures; but comments are always very welcome!
คลังคำ: คู่มือการใช้ภาษาไทยแนวใหม่
Creators: name: กันยรัตน์ สมิตะพินทุ
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2002
Subjects: -

description: วรรณวิทัศน์, 2, พฤศจิกายน, 167-173
A CROSS-SECTION ANALYSIS OF INTRA-INDUSTRY TRADE IN THE U.S. PROCESSED FOOD AND BEVERAGE SECTORS
Creators: name: Hartman, Darcy A.
name: Henderson, Dennis R.
name: Sheldon, Ian M.
name: Hartman, Darcy A.
name: Henderson, Dennis R.
name: Sheldon, Ian M.
Publisher: name: Unknown
Year: 1993
Subjects: International Relations/Trade

description: This paper analyzes the determinants of variation across industries in levels of intra-industry trade (IIT) for a sample of 36 U.S. processed food and beverage industries in 1987, previous studies of intra-industry trade having focused on industry characteristics in the manufacturing sectors. The determinants predicted by IIT theory are measures of product differentiation, economies of scale, and imperfect competition; the results of this analysis indicate that IIT variation across the food and beverage industries is positively related to product differentiation, U.S. total trade, similarity of tariff barriers among trade partners, and economies of scope, but negatively related to industry concentration.
title: A(l)gora: The Mindscape
Creators: name: Xylander, Cheryce von
Publisher: name: Technology and Language, 1(1), 115-125
Year: 2020
Subjects: Cyber-Kant
Mindscape
Algora
Public Space
Philosophy of Mind
Turing Imitation Game
Reason as Composition

description: This essay for the inaugural issue of Technology and Language articulates how we inhabit public space in the critical tradition of the Enlightenment and in the condition of contemporary cyber-technologies. The fabled agora of the ancients has forfeited its intersubjective relevance and imaginary potency. Community no longer hinges on communing: Algorithmic Gate-Keeping is taking command. This paper sounds the bell for a new approach to envisaging social cohesion based on the notion of an “algora,” a term coined to describe a state of affairs that has a longer, largely overlooked, philosophical pedigree. The history of cognitive ideation is also the history of “mindscapes.” They are occasioned by the conjuncture of technology and language, an insight articulated by Kant, formalized by Turing and now practiced by the global citizenry of users, daily hammering out on keyboards what this means in practice.
description: Technology and Language, 1(1), 115-125
Electronic and vibrational Raman spectroscopy of Nd$_{0.5}$Sr$_{0.5}$MnO$_3$ through the phase transitions
Creators: name: Seikh, Md. Motin
name: Sood, A. K.
name: Narayana, Chandrabhas
Publisher: name: arXiv
Year: 2005
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Raman scattering experiments have been carried out on single crystals of Nd$_{0.5}$Sr$_{0.5}$MnO$_3$ as a function of temperature in the range of 320-50 K, covering the paramagnetic insulator-ferromagnetc metal transition at 250 K and the charge-ordering antiferromagnetic transition at 150 K. The diffusive electronic Raman scattering response is seen in the paramagnetic phase which continue to exist even in the ferromagnetic phase, eventually disappearing below 150 K. We understand the existence of diffusive response in the ferromagnetic phase to the coexistence of the different electronic phases. The frequency and linewidth of the phonons across the transitions show significant changes, which cannot be accounted for only by anharmonic interactions.
description: 10 pages, 3 figures published in Pramana - Journal of Physics
Additional file 1 of Need and inequality in the use of health care services in a fragmented and decentralized health system: evidence for Argentina
Creators: name: Palacios, Alfredo
name: Espinola, Natalia
name: Rojas-Roque, Carlos
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Basic indicators. Argentina, Latin American and the Caribbean countries (average) and Organization for Economic Cooperation and Development (OECD) country members (average).
The Syriac letter-forms of ṬūrʻAbdīn and environs
Creators: name: Palmer, Andrew
Publisher: name: Oriens christianus : Hefte für die Kunde des christlichen Orients
Year: 2024

description: Oriens christianus : Hefte für die Kunde des christlichen Orients, Bd. 73 (1989): Oriens christianus, Band 73
Collision cross sections of gas phase DNA ions
Creators: name: Moradian, Annie
Publisher: name: University of British Columbia
Year: 2009

description: The aim of this work is to study the collision cross sections of single stranded DNA ions in an electrospray ionization (ESI) mass spectrometer (MS). In part this work was motivated by a fall-off in signal intensities in ESI-MS with increasing molecular weight of the DNA. The first part of this thesis discusses the theories and experimental methods of measuring and calculating collision cross sections of bio-molecules. The collision cross section is a measure of ion "size" which can provide direct insight to structural characterization of bio-molecules. The second part of this thesis describes experiments with 28-, 40- and 55-mer oligodeoxynucleotide ions and protein ions of nearly the same molecular weight— ubiquitin, cytochrome c and apomyoglobin. The energy losses of ions from collisions with argon were measured and interpreted with a diffuse scattering model. The last part of this thesis presents the comparison of cross sections of oligodeoxynucleotides with cross sections of the proteins. The oligodeoxynucleotides produce negative charge states in ESI similar to he positive charge states produced by the proteins denatured in solution. Cross sections for oligodeoxynucleotide ions increase with charge state similar to those of protein ions. For a given molecular weight and charge state, the cross sections of the oligodeoxynucleotide ions are about 22% lower than those of the proteins. In this study, ESI mass spectra of 28-, 40- and 55-mer oligodexoynucleotides show similar sensitivities and a fall-off in signal intensity with increasing mass has not been observed.
A possible black hole in the gamma-ray microquasar LS 5039
Creators: name: Casares, J.
name: Ribo, M.
name: Ribas, I.
name: Paredes, J. M.
name: Marti, J.
name: Herrero, A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The population of high energy and very high energy gamma-ray sources, detected with EGRET and the new generation of ground-based Cherenkov telescopes, conforms a reduced but physically important sample. Most of these sources are extragalactic (e.g., blazars), while among the galactic ones there are pulsars and SN remnants. The microquasar LS 5039, previously proposed to be associated with an EGRET source by Paredes et al. (2000), has recently been detected at TeV energies, confirming that microquasars should be regarded as a class of high energy gamma-ray sources. To model and understand how the energetic photons are produced and escape from LS 5039 it is crucial to unveil the nature of the compact object, which remains unknown. Here we present new intermediate-dispersion spectroscopy of this source which, combined with values reported in the literature, provides an orbital period of 3.90603+/-0.00017 d, a mass function f(M)=0.0053+/-0.0009 M_sun, and an eccentricity e=0.35+/-0.04. Atmosphere model fitting to the spectrum of the optical companion, together with our new distance estimate of d=2.5+/-0.1 kpc, yields R_opt=9.3+0.7-0.6 R_sun, log (L_opt/L_sun)=5.26+/-0.06, and M_opt=22.9+3.4-2.9 M_sun. These, combined with our dynamical solution and the assumption of pseudo-synchronization, yield an inclination i=24.9+/-2.8 degree and a compact object mass M_X=3.7+1.3-1.0 M_sun. This is above neutron star masses for most of the standard equations of state and, therefore, we propose that the compact object in LS 5039 is a black hole. We finally discuss about the implications of our orbital solution and new parameters of the binary system on the CNO products, the accretion/ejection energetic balance, the SN explosion scenario, and the behaviour of the TeV emission with the new orbital period.
description: 10 pages, 8 figures. Accepted for publication in MNRAS. Minor changes according to referee report
Can WNM survive inside Molecular Clouds ?
Creators: name: Hennebelle, P.
name: Inutsuka, S.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Recent high resolution numerical simulations have suggested that the interstellar atomic hydrogen clouds have a complex two-phase structure. Since molecular clouds form through the contraction of HI gas, the question arises as to whether this structure is maintained in the molecular phase or not. Here we investigate whether the warm neutral atomic hydrogen (WNM) can exist in molecular clouds. We calculate how far a piece of WNM which is not heated by the UV photons could penetrate into the cloud, and find that in the absence of any heating it is unlikely that large fraction of WNM survives inside high pressure molecular clouds. We then consider two possible heating mechanisms, namely dissipation of turbulent energy and dissipation of MHD waves propagating in the WNM inside the cloud. We find that the second one is sufficient to allow the existence of WNM inside a molecular cloud of size $\simeq$ 1 pc having pressure equal to $\simeq 10 \times P_{\rm ISM}$. This result suggests the possibility that channels of magnetised WMN may provide efficient energy injection for sustaining internal turbulence which otherwise decays in a crossing time.
description: accepted for publication in ApJ
Measuring internal forces in single-stranded DNA: Application to a DNA force clamp
Creators: name: Engel, Megan C.
name: Romano, Flavio
name: Louis, Ard A.
name: Doye, Jonathan P. K.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: We present a new method for calculating internal forces in DNA structures using coarse-grained models and demonstrate its utility with the oxDNA model. The instantaneous forces on individual nucleotides are explored and related to model potentials, and using our framework, internal forces are calculated for two simple DNA systems and for a recently-published nanoscopic force clamp. Our results highlight some pitfalls associated with conventional methods for estimating internal forces, which are based on elastic polymer models, and emphasise the importance of carefully considering secondary structure and ionic conditions when modelling the elastic behaviour of single-stranded DNA. Beyond its relevance to the DNA nanotechnological community, we expect our approach to be broadly applicable to calculations of internal force in a variety of structures -- from DNA to protein -- and across other coarse-grained simulation models.
description: 39 pages, 9 figures
Additional file 3 of The Valued Life Activities Scale (VLAs): linguistic validation, cultural adaptation and psychometric testing in people with rheumatic and musculoskeletal diseases in the UK
Creators: name: Prior, Y.
name: A. Tennant
name: S. Tyson
name: A. Hammond
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3. British Valued Life Activities Scale [British VLAs].
The GAPS Programme at TNG -- XXIV. An eccentric Neptune-mass planet near the inner edge of the BD-11 4672 habitable zone
Creators: name: Barbato, D.
name: Pinamonti, M.
name: Sozzetti, A.
name: Biazzo, K.
name: Benatti, S.
name: Damasso, M.
name: Desidera, S.
name: Lanza, A. F.
name: Maldonado, J.
name: Mancini, L.
name: Scandariato, G.
name: Affer, L.
name: Andreuzzi, G.
name: Bignamini, A.
name: Bonomo, A. S.
name: Borsa, F.
name: Carleo, I.
name: Claudi, R.
name: Cosentino, R.
name: Covino, E.
name: Fiorenzano, A. F. M.
name: Giacobbe, P.
name: Harutyunyan, A.
name: Knapic, C.
name: Leto, G.
name: Lorenzi, V.
name: Maggio, A.
name: Malavolta, L.
name: Micela, G.
name: Molinari, E.
name: Molinaro, M.
name: Nascimbeni, V.
name: Pagano, I.
name: Pedani, M.
name: Piotto, G.
name: Poretti, E.
name: Rainer, M.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: With the growth of comparative exoplanetology, it is increasingly clear that investigating the relationships between inner and outer planets plays a key role in discriminating between competing formation and evolution models. To do so, it is important to probe the inner region of systems hosting long-period giants in search for undetected lower-mass planetary companions. In this work we present our results on the K-dwarf star BD-11~4672, already known to host a long-period giant planet, as the first output of a subsample of the GAPS programme specifically aimed at assessing the impact of inefficient migration of planets formed beyond the snowline by searching for Neptune-mass and super-Earths planetary companions of known longer-period giants. The high-precision HARPS-N observations of BD-11~4672 are used in conjunction with literature time series in order to search for additional inner planetary signals to be fitted using differential evolution Markov chain Monte Carlo. The long-term stability of the new orbital solutions is tested by N-body dynamical simulations. We report the detection of BD-11~4672~c, a new Neptune-mass planet with an orbital period of $74.20_{-0.08}^{+0.06}\,\rm{d}$, eccentricity $0.40_{-0.15}^{+0.13}$, semimajor axis $0.30\pm0.01\,\rm{au}$ and minimum mass $15.37_{-2.81}^{+2.97}\,M_\oplus$ orbiting slightly outside the inner edge of the optimistic circumstellar habitable zone. In order to assess its impact on the dynamical stability of the habitable zone we compute the angular momentum deficit of the system, showing that planet c has a severe negative impact on the stability of possible additional lower-mass temperate planets. The BD-11~4672 system is notable for its architecture, hosting both a long-period giant planet and an inner lower-mass planet, the latter being also among the most eccentric Neptune-mass planets known at similar periods.
description: 16 pages, 12 Figures. Accepted for publication on A&A
Ein syrischer Brief aus dem 9. Jahrhundert über die kirchenrechtliche Oikonomia
Creators: name: Kaufhold, Hubert
Publisher: name: Oriens christianus : Hefte für die Kunde des christlichen Orients
Year: 2024

description: Oriens christianus : Hefte für die Kunde des christlichen Orients, Bd. 73 (1989): Oriens christianus, Band 73
Additional file 1 of The Valued Life Activities Scale (VLAs): linguistic validation, cultural adaptation and psychometric testing in people with rheumatic and musculoskeletal diseases in the UK
Creators: name: Prior, Y.
name: A. Tennant
name: S. Tyson
name: A. Hammond
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. VLAs Published Versions and Psychometric Testing.
se(3)-TrackNet: Data-driven 6D Pose Tracking by Calibrating Image Residuals in Synthetic Domains
Creators: name: Wen, Bowen
name: Mitash, Chaitanya
name: Ren, Baozhang
name: Bekris, Kostas E.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Graphics (cs.GR)
subject: Machine Learning (cs.LG)
subject: Robotics (cs.RO)
subject: Image and Video Processing (eess.IV)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Tracking the 6D pose of objects in video sequences is important for robot manipulation. This task, however, introduces multiple challenges: (i) robot manipulation involves significant occlusions; (ii) data and annotations are troublesome and difficult to collect for 6D poses, which complicates machine learning solutions, and (iii) incremental error drift often accumulates in long term tracking to necessitate re-initialization of the object's pose. This work proposes a data-driven optimization approach for long-term, 6D pose tracking. It aims to identify the optimal relative pose given the current RGB-D observation and a synthetic image conditioned on the previous best estimate and the object's model. The key contribution in this context is a novel neural network architecture, which appropriately disentangles the feature encoding to help reduce domain shift, and an effective 3D orientation representation via Lie Algebra. Consequently, even when the network is trained only with synthetic data can work effectively over real images. Comprehensive experiments over benchmarks - existing ones as well as a new dataset with significant occlusions related to object manipulation - show that the proposed approach achieves consistently robust estimates and outperforms alternatives, even though they have been trained with real images. The approach is also the most computationally efficient among the alternatives and achieves a tracking frequency of 90.9Hz.
SCALE ECONOMIES AND IMPERFECT COMPETITION IN THE GTAP MODEL
Creators: name: Francois, Joseph F.
name: Francois, Joseph F.
Publisher: name: Unknown
Year: 1998
Subjects: International Relations/Trade

description: The universe of existing CGE models can be divided into 3 broad categories. The first class of models (of which the standard GTAP model is a classic example) emphasizes the static effects of policy related to general equilibrium resource reallocation. The second involves scale economics and imperfect competition and the third involves dynamic accumulation effects. Development of the second class of models has followed a long period during which many of the basic tenants of modern industrial organization theory were integrated into the core of mainstream trade theory. The resulting class of applied models emphasizes procompetitive effects. This paper presents techniques for the incorporation of several stylized representations of scale economies and imperfect competition into the GTAP modeling framework. A numerical example is also provided.
LONG RUN SIMULATIONS WITH GTAP: ILLUSTRATIVE RESULTS FROM APEC TRADE LIBERALISATION
Creators: name: Walmsley, Terrie L.
name: Walmsley, Terrie L.
Publisher: name: Unknown
Year: 1998
Subjects: International Relations/Trade

description: In static applied general equilibrium models, the exogenous/endogenous split between variables (or closure) is used to infer the time frame over which the effects of a shock are simulated. This paper introduces a long-run closure for the GTAP model (Hertel and Tsigas, 1997) and uses this closure to simulate and compare the short-run and long-run effects of Asia-Pacific trade liberalisation. The approach explored here incorporates some relatively minor changes to existing GTAP theory in order to define a steady state in which growth rates of all real variables are uniform. Such uniformity must apply in the initial database (as well as in the post-shock solution). So to implement the new long run in GTAP a new initial database must first be created. Details concerning the creation of the new database are given, and results under the new approach are compared with those obtained under the old. The emphasis of this paper is on the development of a long-run closure in which the percentage change form equations of the model and the relationships between the levels variables in the GTAP database are consistent. Further research is required into these types of long-run closures to incorporate changes in ownership of capital to ensure that changes in welfare are adequately modelled. In the results reported here, GDP is not a useful guide to national welfare. The long-run closures introduced here are also compared with another comparative static long-run closure developed for GTAP by Francois, MacDonald and Nordström (1996).
IMPLEMENTING QUOTAS IN GTAP USING GEMPACK OR HOW TO LINEARIZE AN INEQUALITY
Creators: name: Pearson, Ken
name: Bach, Christian Friis
name: Pearson, Ken
name: Bach, Christian Friis
Publisher: name: Unknown
Year: 1996
Subjects: International Relations/Trade

description: This document describes how explicit import and export quotas can be implemented and solved in the GTAP CGE trade model. The techniques described here apply equally well to other general and partial equilibrium models implemented and solved using the GEMPACK software. They also generalise to procedures for handling other inequalities in models solved via GEMPACK (even though GEMPACK does not allow explicit inequalities in the algebraic representation of models). In this document we review some recent applications of GTAP in which explicit import and export quotas have been modelled, and discuss how important it was for these applications to have explicit treatment of quotas. Accompanying this document are various computer files containing the ingredients of examples that readers can carry out for themselves while reading this paper. These files can also be used as a starting point for those who wish to explicitly model quotas in their own models.
Training Variational Networks with Multi-Domain Simulations: Speed-of-Sound Image Reconstruction
Creators: name: Bernhardt, Melanie
name: Vishnevskiy, Valery
name: Rau, Richard
name: Goksel, Orcun
Publisher: name: arXiv
Year: 2020
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Medical Physics (physics.med-ph)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Speed-of-sound has been shown as a potential biomarker for breast cancer imaging, successfully differentiating malignant tumors from benign ones. Speed-of-sound images can be reconstructed from time-of-flight measurements from ultrasound images acquired using conventional handheld ultrasound transducers. Variational Networks (VN) have recently been shown to be a potential learning-based approach for optimizing inverse problems in image reconstruction. Despite earlier promising results, these methods however do not generalize well from simulated to acquired data, due to the domain shift. In this work, we present for the first time a VN solution for a pulse-echo SoS image reconstruction problem using diverging waves with conventional transducers and single-sided tissue access. This is made possible by incorporating simulations with varying complexity into training. We use loop unrolling of gradient descent with momentum, with an exponentially weighted loss of outputs at each unrolled iteration in order to regularize training. We learn norms as activation functions regularized to have smooth forms for robustness to input distribution variations. We evaluate reconstruction quality on ray-based and full-wave simulations as well as on tissue-mimicking phantom data, in comparison to a classical iterative (L-BFGS) optimization of this image reconstruction problem. We show that the proposed regularization techniques combined with multi-source domain training yield substantial improvements in the domain adaptation capabilities of VN, reducing median RMSE by 54% on a wave-based simulation dataset compared to the baseline VN. We also show that on data acquired from a tissue-mimicking breast phantom the proposed VN provides improved reconstruction in 12 milliseconds.
ADJUSTING TAX RATES IN THE GTAP DATA BASE
Creators: name: Malcolm, Gerard
name: Malcolm, Gerard
Publisher: name: Unknown
Year: 1998
Subjects: International Relations/Trade

description: This paper describes a procedure designed for incorporating improved information on taxes into existing GTAP data aggregations. The aim of this procedure is to maintain the internal consistency of the data base while minimizing the impacts of the tax change on the value flows in the data base. It utilizes a variant of the GTAP model, for which the model structure and parameter settings have been designed to achieve this aim. The features include Cobb-Douglas production and consumption functions, inter-intermediate input substitution (also Cobb-Douglas), universal factor mobility and fixed trade balances.
DISAGGREGATING LABOR PAYMENTS BY SKILL LEVEL IN GTAP
Creators: name: Liu, Jing
name: Van Leeuwen, Nico
name: Vo, Tri Thanh
name: Tyers, Rodney
name: Hertel, Thomas W.
name: Liu, Jing
name: Van Leeuwen, Nico
name: Vo, Tri Thanh
name: Tyers, Rodney
name: Hertel, Thomas W.
Publisher: name: Unknown
Year: 1998
Subjects: International Relations/Trade
Labor and Human Capital

description: This paper outlines an approach to disaggregating labor payments in the GTAP, global economic data base. The split between low- and high-skilled labor is based on occupational data. High-skilled labor is assumed to consist of managers, administrators, professionals, and para-professionals. Data are gathered on this occupational split, by sector, in fifteen different economies, and these are mapped to GTAP sectors. Regression analysis shows a systematic relationship between GDP per capita and the national stock of tertiary and secondary educated labor on the one hand, and the sectoral labor payments split on the other. This model is used to predict labor splits, by sector, in the remaining GTAP regions. The results are evaluated in terms of the implied economywide skilled -unskilled labor payment ratio. Overall, the results seem promising enough to warrant inclusion in the GTAP, version 4 data base.
THEORETICAL STRUCTURE OF DYNAMIC GTAP
Creators: name: Ianchovichina, Elena
name: McDougall, Robert
name: Ianchovichina, Elena
name: McDougall, Robert
Publisher: name: Unknown
Year: 2000
Subjects: International Relations/Trade

description: This paper documents the foreign asset ownership and investment theory of the dynamic GTAP model (GTAP-Dyn). The new investment theory offers a disequilibrium approach to modeling endogenously international capital mobility. It permits a recursive solution procedure, a feature that allows easy implementation of dynamics into any static AGE model without imposing limitations on the model's size. The method involves treating time as a variable, not as an index. having time as a variable allows the construction of dynamic GTAP with minimum modifications to the existing structure of GTAP, by separating the theory of static GTAP from the length of run.
A GENERAL WELFARE DECOMPOSITION FOR CGE MODELS
Creators: name: Hanslow, Kevin
name: Hanslow, Kevin
Publisher: name: Unknown
Year: 2000
Subjects: International Relations/Trade

description: Huff and Hertel (2001) derive a welfare decomposition for the equivalent variation in the GTAP model. The derivation appears to be very specific to GTAP. Nevertheless, it contains nearly all the ingredients required for performing welfare decomposition for any CGE model. In this paper, the approach of Huff and Hertel (2001) is generalised to derive a welfare decomposition that can be applied to most, if not all, CGE models. General production and utility functions are accommodated, as are foreign income flows. A brief guide to coding the proposed welfare decomposition in GEMPACK is also provided. The decomposition is applied to decomposing the equivalent variation in GTAP.
GTAP-DD: A MODEL FOR ANALYZING TRADE REFORMS IN THE PRESENCE OF DUTY DRAWBACKS
Creators: name: Ianchovichina, Elena
name: Ianchovichina, Elena
Publisher: name: Unknown
Year: 2003
Subjects: International Relations/Trade

description: Duty drawback schemes, which typically involve a combination of duty rebates and exemptions, are a feature of many countries' trade regimes. They are used in highly protected, developing economies as means of providing exporters with imported inputs at world prices, and thus increasing their competitiveness, while maintaining the protection on the rest of the economy. In China duty exemptions have been central to the process of trade reform and have led to a tremendous increase in processed exports utilizing imported materials. Despite the widespread use and importance of duty drawbacks, these "new trade liberalization" instruments have been given relatively little attention in empirical multilateral trade liberalization studies. This paper presents an empirical multi-region trade model GTAP-DD, an extension of GTAP, in which the effects of policy reform are differentiated based on the trade-orientation of the firms. Both GTAP and GTAP-DD are used to analyze the impact of China's WTO accession, which involves liberalization in China from 1997 to post-accession tariffs among a number of other liberalization measures. The analysis shows that failure to account of duty exemptions in the case of China's recent WTO accession will overstate the increase in : (a) China's trade flows by 40 percent, (b) China's welfare by 15 percent, and (c) exports of selected sectors by as much as 90 percent. The magnitude of the bias depends on the level of pre-intervention tariffs and the size of tariff cuts - the larger the initial distortions and tariff reductions, the larger the bias when duty drawbacks are ignored. The bias in GTAP's estimates of China's real GDP, trade flows and welfare changes due to WTO accession increases more three times when China's pre-intervention tariffs are raised from their 1997 levels to the much higher 1995 levels. These results suggest that trade liberalization studies focusing on economies in which protection is high, import concessions play an important role and planned tariff cuts are deep, must treat duty drawbacks explicitly in order to avoid serious errors in their estimates of sectoral, trade flows and welfare changes.
Multi-Task Learning for Multi-Dimensional Regression: Application to Luminescence Sensing
Creators: name: Umberto
name: Michelucci
name: Venturini, Francesca
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The classical approach to non-linear regression in physics, is to take a mathematical model describing the functional dependence of the dependent variable from a set of independent variables, and then, using non-linear fitting algorithms, extract the parameters used in the modeling. Particularly challenging are real systems, characterized by several additional influencing factors related to specific components, like electronics or optical parts. In such cases, to make the model reproduce the data, empirically determined terms are built-in the models to compensate for the impossibility of modeling things that are, by construction, impossible to model. A new approach to solve this issue is to use neural networks, particularly feed-forward architectures with a sufficient number of hidden layers and an appropriate number of output neurons, each responsible for predicting the desired variables. Unfortunately, feed-forward neural networks (FFNNs) usually perform less efficiently when applied to multi-dimensional regression problems, that is when they are required to predict simultaneously multiple variables that depend from the input dataset in fundamentally different ways. To address this problem, we propose multi-task learning (MTL) architectures. These are characterized by multiple branches of task-specific layers, which have as input the output of a common set of layers. To demonstrate the power of this approach for multi-dimensional regression, the method is applied to luminescence sensing. Here the MTL architecture allows predicting multiple parameters, the oxygen concentration and the temperature, from a single set of measurements.
description: 16 Pages
Canonical Form and Separability of PPT States on Multiple Quantum Spaces
Creators: name: Wang, Xiao-Hong
name: Fei, Shao-Ming
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: By using the "subtracting projectors" method in proving the separability of PPT states on multiple quantum spaces, we derive a canonical form of PPT states in ${\Cb}^{K_1} \otimes {\Cb}^{K_2} \otimes ... \otimes {\Cb}^{K_m} \otimes {\Cb}^N$ composite quantum systems with rank $N$, from which a sufficient separability condition for these states is presented.
description: 5 pages
Advanced Strategies of Portfolio Management in the Heston Market Model
Creators: name: Gruszka, Jarosław
name: Szwabiński, Janusz
Publisher: name: arXiv
Year: 2020
Subjects: subject: Portfolio Management (q-fin.PM)
subject: FOS: Economics and business
subject: 91G10, 91G60

description: There is a great number of factors to take into account when building and managing an investment portfolio. It is widely believed that a proper set-up of the portfolio combined with a good, robust management strategy is the key to successful investment. In this paper, we aim at an analysis of two aspects that may have an impact on investment performance: diversity of assets and inclusion of cash in the portfolio. We also propose two new management strategies based on the MACD and RSI factors known from technical analysis. Monte Carlo simulations within the Heston model of a market are used to perform numerical experiments.
description: 22 pages, 9 figures
Additional file 2 of The Valued Life Activities Scale (VLAs): linguistic validation, cultural adaptation and psychometric testing in people with rheumatic and musculoskeletal diseases in the UK
Creators: name: Prior, Y.
name: A. Tennant
name: S. Tyson
name: A. Hammond
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. Original VLAs items vs the British VLAs items.