cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The generalized Mukai conjecture for symmetric varieties
Creators: name: Gagliardi, Giuliano
name: Hofscheier, Johannes
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14M27, 14J45, 14L30, 52B20

description: We associate to any complete spherical variety $X$ a certain nonnegative rational number $\wp(X)$, which we conjecture to satisfy the inequality $\wp(X) \le \operatorname{dim} X - \operatorname{rank} X$ with equality holding if and only if $X$ is isomorphic to a toric variety. We show that, for spherical varieties, our conjecture implies the generalized Mukai conjecture on the pseudo-index of smooth Fano varieties due to Bonavero, Casagrande, Debarre, and Druel. We also deduce from our conjecture a smoothness criterion for spherical varieties. It follows from the work of Pasquier that our conjecture holds for horospherical varieties. We are able to prove our conjecture for symmetric varieties.
description: 33 pages, 2 figures, 6 tables
Development, validation and use of an insulin sensitivity score in youths with diabetes: the SEARCH for Diabetes in Youth study
Creators: name: Klingensmith, G.
name: Knowler, W. C.
name: West, N.
name: Maahs, D.
name: Dabelea, D.
name: Mason, C. C.
name: D’Agostino, R. B.
name: Hamman, R. F.
name: Mayer-Davis, E. J.
name: Nadeau, K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The ability to measure insulin sensitivity across the phenotypic spectrum of diabetes may contribute to a more accurate characterisation of diabetes type. Our goal was to develop and validate an insulin sensitivity (IS) score using the euglycaemic–hyperinsulinaemic clamp in a subset (n=85) of 12– to 19-year-old youths with diabetes participating in the SEARCH study in Colorado, USA.
XMM-Newton and Chandra observations of the M31 globular cluster black hole candidate XB135: a heavyweight contender cut down to size
Creators: name: Barnard, R.
name: Primini, F.
name: Garcia, M. R.
name: Kolb, U. C.
name: Murray, S. S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: CXOM31 J004252.030+413107.87 is one of the brightest X-ray sources within the D_25 region of M31, and associated with a globular cluster (GC) known as B135; we therefore call this X-ray source XB135. XB135 is a low mass X-ray binary (LMXB) that apparently exhibited hard state characteristics at 0.3--10 keV luminosities 4--6 E+38 erg/s, and the hard state is only observed below ~10% Eddington. If true, the accretor would be a high mass black hole (BH) (> ~50 M_Sun); such a BH may be formed from direct collapse of a metal-poor, high mass star, and the very low metalicity of B135 (0.015 Z_Sun) makes such a scenario plausible. We have obtained new XMM-Newton and Chandra HRC observations to shed light on the nature of this object. We find from the HRC observation that XB135 is a single point source located close to the center of B135. The new XMM-Newton spectrum is consistent with a rapidly spinning ~10--20 M_Sun BH in the steep power law or thermal dominant state, but inconsistent with the hard state that we previously assumed. We cannot formally reject three component emission models that have been associated with high luminosity neutron star LMXBs (known as Z-sources); however, we prefer a BH accretor. We note that deeper observation of XB135 could discriminate against a neutron star accretor.
description: Accepted for publication in ApJ; 8 pages, 6 figures
Age at menarche and risk of type 2 diabetes among African-American and white women in the Atherosclerosis Risk in Communities (ARIC) study
Creators: name: Huxley, R.
name: Lutsey, P. L.
name: Dreyfus, J. G.
name: Franceschini, N.
name: Fernández-Rhodes, L.
name: Selvin, E.
name: Demerath, E. W.
name: Pankow, J. S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: We examined race differences in the association between age at menarche and type 2 diabetes before and after adjustment for adiposity.
'Some things you mite like to know...' Textiles as a medium for raising awareness about scabies; an interdisciplinary approach
Creators: name: Haffenden, Vikki
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study
Creators: name: Fujimoto, W.
name: Imperatore, G.
name: Andrews, J. S.
name: Hamman, R. F.
name: Dolan, L. M.
name: Mayer-Davis, E. J.
name: Dabelea, D.
name: D’Agostino, R.
name: Linder, B.
name: Marcovina, S.
name: Pihoker, C.
name: Greenbaum, C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Few studies have explored the epidemiology of beta cell loss in youth with diabetes. This report describes the evolution and major determinants of beta cell function, assessed by fasting C-peptide (FCP), in the SEARCH for Diabetes in Youth study.
Making or not making in new disciplinary educations
Creators: name: Håkanson, Lena
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Measles: a new danger for Ukraine's children! The need for an effective and timely vaccination prevention campaign.
Creators: name: Orsini, Davide
name: Martini, Mariano
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Ukraine
children
infectious diseases
refugee
vaccine hesitancy
vaccine awareness campaign
infectious diseases and measles

description: Abstract Background: Measles, a highly contagious and dangerous disease that can cause disability or even death, remains endemic in Ukraine. This is a serious public health problem that absolutely needs to be monitored. Indeed, in the years 2017-2019, Ukraine was hit by a major measles epidemic, which caused serious problems for the population. The numerous efforts to contain the spread of measles in the country are now waning in the face of a devastating war, which has already lasted for over a year, and the Covid-19 pandemic, which has further complicated the general situation. Method: In this paper, the authors highlight a very serious public health problem and invoke the immediate implementation of an effective vaccination policy. Discussion: The percentages of measles vaccination coverage in Ukraine have decreased drastically since the beginning of the conflict (which began on February 24, 2022), and this is a source of concern regarding the possibility of a new major measles epidemic. Indeed, a measles epidemic at this time would have frightening consequences, given the conditions in which the Ukrainian population is now living. The United Nations estimates that at least 6 million people have been displaced within Ukraine as a result of the conflict, and this internal mass exodus has significantly affected vaccination coverage and adherence to vaccination schedules, despite the efforts of the Ukrainian health authorities. Conclusion. The ministry of health has prioritized vaccination programs with the help of the World Health Organization (WHO) and UNICEF, which are ensuring the free supply and delivery of vaccines through the deployment of mobile vaccination teams, even in areas where health facilities are not accessible. The main objective is to vaccinate as many people as possible in order to avoid a new epidemic, which could spread to the whole of Ukraine and also to other countries.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
Two-neutrino double-beta decay of $^{150}$Nd to excited final states in $^{150}$Sm
Creators: name: Kidd, Mary F.
name: Esterline, James H.
name: Finch, Sean W.
name: Tornow, Werner
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Double-beta decay is a rare nuclear process in which two neutrons in the nucleus are converted to two protons with the emission of two electrons and two electron anti-neutrinos. We measured the half life of the two-neutrino double-beta decay of $^{150}$Nd to excited final states of $^{150}$Sm by detecting the de-excitation gamma rays of the daughter nucleus. This study yields the first detection of the coincidence gamma rays from the 0$^+_1$ excited state of $^{150}$Sm. These gamma rays have energies of 333.97 keV and 406.52 keV, and are emitted in coincidence through a 0$^+_1\rightarrow$2$^+_1\rightarrow$0$^+_{gs}$ transition. The enriched Nd$_2$O$_3$ sample consisted of 40.13 g $^{150}$Nd and was observed for 642.8 days at the Kimballton Underground Research Facility, producing 21.6 net events in the region of interest. This count rate gives a half life of $T_{1/2}=(1.07^{+0.45}_{-0.25}(stat)\pm0.07(syst.))\times 10^{20}$ years. The effective nuclear matrix element was found to be 0.0465$^{+0.0098}_{-0.0054}$. Finally, lower limits were obtained for decays to higher excited final states. Our half-life measurement agrees within uncertainties with another recent measurement in which no coincidence was employed. Our nuclear matrix element calculation may have an impact on a recent neutrinoless double-beta decay nuclear matrix element calculation which implies the decay to the first excited state in $^{150}$Sm is favored over that to the ground state.
description: 16 pages, 15 figures
Disruption of the association of integrin-associated protein (IAP) with tyrosine phosphatase non-receptor type substrate-1 (SHPS)-1 inhibits pathophysiological changes in retinal endothelial function in a rat model of diabetes
Creators: name: Clemmons, D.
name: Wai, C.
name: Maile, L. A.
name: Byfield, G.
name: Hartnett, M. E.
name: Gollahon, K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Our studies have shown that the association between integrin-associated protein (IAP) and SHPS-1 regulates the response of cells including osteoclasts, osteoblasts, smooth muscle and retinal endothelial cells to Insulin-like growth factor-I (IGF-I). The aims of this study were to determine whether the regulation of IGF-I responsiveness by IAP/SHPS-1 association is a generalized response of endothelial cells, to identify the mechanism by which IAP/SHPS-1 association contributes to changes in endothelial cell responses to IGF-I and to determine whether inhibiting their association alters pathophysiologic changes that occur in vivo.
Fenofibrate-associated changes in renal function and relationship to clinical outcomes among individuals with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) experience
Creators: name: Ginsberg, H. N.
name: Buse, J.
name: Bonds, D. E.
name: Crouse, J. R.
name: O’Connor, P. J.
name: Cuddihy, R.
name: Kirchner, K.
name: Craven, T. E.
name: Marcovina, S.
name: Elam, M.
name: Mychaleckyj, J. C.
name: Sperl-Hillen, J.-A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Fenofibrate has been noted to cause an elevation in serum creatinine in some individuals. Participants in the Action to Control Cardiovascular Risk in Diabetes Lipid Study were studied to better characterise who is at risk of an increase in creatinine level and to determine whether those with creatinine elevation have a differential risk of adverse renal or cardiovascular outcomes.
title: Numerical modelling of morphological impacts of off�shore wind farms
Creators: name: Christie, Elizabeth
Publisher: name: University of Liverpool Repository
Year: 2015

description: Demand for renewable energy resources to reduce greenhouse gases for EU targets, has led to a recent rapid development of Offshore Wind Farms (OWF). As OWFs become larger and multiple sites are developed, it becomes increasingly important to determine the wind farms impact on the coastal environment for design and planning. It is well established that the wind turbine monopiles at OWFs modify the flow in the localised area of the structure, to create a complex 3D flow structure, which ultimately results in scour hole formation. This present research aims to determine the impact of an OWF at both the localised and coastal scale through large scale modelling with the structures represented as islands in the mesh. This method is thought to be an improvement on the typical method of representing the structures as a resistance term in the grid, as it is able to capture some of the complex flow at the structure. The TELEMAC modelling package is used, with the hydrodynamics determined by the TELEMAC-3D module, the waves by the TOMAWAC module, and sediment transport by the SISYPHE module. Validation of the model at the structure showed good agreement with empirical data in the near field of the structure. Tidal flows are well predicted across the water depth, whilst scour formation is well predicted in front of the pile, there are areas of accretion in the wake which are unexpected. The large scale impact of the wind farm on coastal processes was assessed and compared over two wind farm sites, representing different coastal environments. The Burbo Bank wind farm is situated in a coastal bay, whereas Scroby Sands OWF is an open coast site. In both cases the wind farm was seen to block the flow and influence the large scale coastal sediment pathways. At Burbo Bank the wind farm enabled stirring of sediment into suspension, and influenced the sediment transport over the south east corner of Liverpool Bay. The Scroby Sands wind farm was found to reduce the sediment flux magnitude in the vicinity of the array. The long term morphological impact is also determined for the Burbo Bank OWF over a year period, with a morphological acceleration factor. Two methods are compared for generation of a set of representative waves, based on frequency of occurrence and wave energy. Both methods indicate that over a year period the wind farm has a large influence on sediment transport pathways, and increases sediment flux across the Great Burbo Flats. Maximum scour depth predictions at the structures showed good agreement with empirical formula. The pattern of scour for the representative waves based on frequency of occurrence, fits well with measured scour at the wind farm array.
title: HCCI engine modelling for control
Creators: name: Jia, Nan
Publisher: name: University of Liverpool Repository
Year: 2023

description: To meet future environmental challenges and more stringent emISSIOn legislation, Homogeneous Charge Compression Ignition (HCCI) has been proposed as a promising alternative to conventional combustion strategies. Heel engines offer thermal efficiencies comparable to those attained by high compression ratio diesel engines while maintaining the smoke free operation of spark ignition engines. HCel engines operate on the principle of having a premixed charge that auto-ignites and burns spontaneously throughout the cylinder as it is compressed by the piston. However, combustion control is a significant challenge for Heel engines that must be solved if they are to become a commercial success. In order to investigate the control strategies for solving the fundamental challenges, the original project specification set by the sponsor, Jaguar Cars Ltd, does not require that the models predict the HeCI combustion in every detailed aspect, but the models must be sufficient to capture most control relevant behaviours of HCCI process and are desired an inherent simple structure to reduce the simulation time. This thesis summarises research work in the development of HeCI engine models for control purposes. The work was initially inspired from the investigations of Heel research development that introduces the technologies to achieve Heel combustion and reviews the modelling approaches by different methodologies. The single-zone model was proposed and utilised with Arrhenius-type equations to describe the process of propane combustion. And then, gasoline fuelled HCCI engine was developed by utilising Wiebe function and using Genetic Algorisms (GAs) to identify unknown parameters in the combustion segments. The relevant simulation results show that the models are able to adequately simulate the combustion process and capture the combustion timing and in-cylinder pressure evolution. The aforementioned models were extended to investigate the general behaviours of the HCCI dynamic process, including cycle-to-cycle coupling, modulating the inducted gases composition and cyclic in-cylinder pressure evolutions. After the extensive simulation studies were conducted, a vehicle driveline model was then integrated into the model to investigate the feasible control strategy. By applying a simple proportional-integral controller, the vehicle velocity and engine output were both controlled by modulating intake and exhaust valves timing. The successful cycle-resolved simulation results indicate that the simplifications inherent in the model are not critical to the successful prediction of trend of ignition timing, work output variation and cyclic coupling - the most challenging problems of HCCI engines. Furthermore, the reduced complexity of the simulation offers the prospect of achieving simulation speeds that will allow real time predictions so that the model can be used as a practical engineering tool and a valuable testing facility In the development of suitable control strategies
title: Spiral growth manufacture : a continuous additive manufacturing technology for powder processing
Creators: name: J. Egan, M.
Publisher: name: University of Liverpool Repository
Year: 2023

description: Layered manufacturing (LM) technologies are a class of additive manufacturing processes which create three dimensional geometries directly from CAD data sequentially layer by layer. This group of technologies can process a variety of metallic, polymer and ceramic materials, as liquids, powders, or solid sheets or filaments. The material can be processed using a laser, such as melting a powder or curing a polymer resin or consolidated using a binder deposited from a print head. The build methodology used in all LM is fundamentally a start-stop process since the deposition of material and processing of each layer occurs ~equentially. Hence, the build rate can be slow (2 - 6 Layers per minute); consequently, LM technologies have largely found application as prototyping tools to speed up product development. In order for these technologies to be adopted as rapid manufacturing (RM) methods to directly manufacture complex components which cannot be manufactured by other means these speed limitations need to be addressed. This Thesis describes a new high speed RM process, Spiral Growth Manufacturing (SGM), whereby 3D parts are built by simultaneously depositing, levelling and selectively consolidating thin powder layers onto a rotating build platform. This build configuration has several advantages when compared to conventional layered manufacturing systems: firstly, the process is continuous with no layer preparation overheads; secondly, the material deposition and solidification process can be performed simultaneously by the addition of further 'build stations' radially distributed about the circumference of the machine. The work presented in this thesis focused on the design, development and testing ofthe Spiral Growth Manufacturing process. Two machines were developed; one used a bank of stationary inkjet heads to print material, either as a binder into a powder layer or as hard material from mixing two printed ink solutions and the other machine used a 90 W, flash lamp pumped Nd:YAG laser to process metal powders by localised melting. The main objective ofthe testing phase was to produce simple 3D objects from solidified layers by: a) ink jet printing a binding agent into the deposited plaster powder layers; and b) ink jet printing reactive materials to form plaster directly. The second machine was developed to exploit the considerable knowledge of Selective Laser Melting (SLM) at Liverpool, with the modification of a research SLM machine to SGM operation.
Multilevel examination of diabetes in modernising China: what elements of urbanisation are most associated with diabetes?
Creators: name: Meigs, J. B.
name: Gordon-Larsen, P.
name: Popkin, B. M.
name: Attard, S. M.
name: Mayer-Davis, E. J.
name: Herring, A. H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Aims/hypothesisThe purpose of this study was to examine the association between urbanisation-related factors and diabetes prevalence in China.MethodsAnthropometry, fasting blood glucose (FBG) and community-level data were collected for 7,741 adults (18–90years) across 217 communities and nine provinces in the 2009 China Health and Nutrition Survey to examine diabetes (FBG ≥7.0mmol/l or doctor diagnosis). Sex-stratified multilevel models, clustered at the community and province levels and controlling for individual-level age and household income were used to examine the association between diabetes and: (1) a multicomponent urbanisation measure reflecting overall modernisation and (2) 12 separate components of urbanisation (e.g., population density, employment, markets, infrastructure and social factors).ResultsPrevalent diabetes was higher in more-urbanised (men 12%; women 9%) vs less-urbanised (men 6%; women 5%) areas. In sex-stratified multilevel models adjusting for residential community and province, age and household income, there was a twofold higher diabetes prevalence in urban vs rural areas (men OR 2.02, 95% CI 1.47, 2.78; women, OR 1.94, 95% CI 1.35, 2.79). All urbanisation components were positively associated with diabetes, with variation across components (e.g. men, economic and income diversity, OR 1.42, 95% CI 1.20, 1.66; women, transportation infrastructure, OR 1.18, 95% CI 1.06, 1.32). Community-level variation in diabetes was comparatively greater for women (intraclass correlation [ICC] 0.03–0.05) vs men (ICC ≤0.01); province-level variation was greater for men (men 0.03–0.04; women 0.02).Conclusions/interpretationDiabetes prevention and treatment efforts are needed particularly in urbanised areas of China. Community economic factors, modern markets, communications and transportation infrastructure might present opportunities for such efforts.Electronic supplementary materialThe online version of this article (doi:10.1007/s00125-012-2697-8) contains peer-reviewed but unedited supplementary material, which is available to authorised users.
Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice
Creators: name: Zhu, L.
name: Luther, J. M.
name: Dematteo, A.
name: Stafford, J. M.
name: Wang, Z.
name: Pozzi, A.
name: Wang, A.
name: Luo, P.
name: Kim, H.-S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Obesity is associated with aldosterone excess, hypertension and the metabolic syndrome, but the relative contribution of aldosterone to obesity-related complications is debated. We previously demonstrated that aldosterone impairs insulin secretion, and that genetic aldosterone deficiency increases glucose-stimulated insulin secretion in vivo. We hypothesised that elimination of endogenous aldosterone would prevent obesity-induced insulin resistance and hyperglycaemia.
D3.6 Fellowship programme, governance structure and business model for SWForum.eu – v1
Creators: name: Di Nitto, Elisabetta
Publisher: name: Zenodo
Year: 2020
Subjects: Fellowship programme
Business model
software
online forum

description: This deliverable constitutes the first result produced by task T3.3 - Definition and creation of a Governance structure and business model - in the context of the SwForum project. The main objective of the task is to define the approach, governance structure, and business model for the Forum of researchers that constitutes one of the main results of the project. This Forum will be based on two main ingredients: the participation to the Forum of well-known fellows in the European panorama of software engineering and a governance structure and business model that will set the basis for the self-sustainability of the Forum beyond the lifetime of the project. Consistently with these objectives, the purpose of this deliverable is twofold. On the one side, it defines the strategy we aim at adopting for involving new fellows in the work of the Forum. On the other side, it presents the landscape analysis performed by the SwForum consortium in the area of various types of scientific and technical associations in the area of Information Technology. The purpose of this analysis is to learn from other experiences and identify the best strategy to build a self-sustainable association. The deliverable starts with an introduction (Section 1) where context and objectives are set. Section 2 defines the preliminary objectives of the Forum. Section 3 presents the analysis of the associations we have considered. Section 4 presents the preliminary lessons learnt. Section 5 defines the strategy for the fellowship programme. Finally, Section 6 draws the conclusions and defines a plan for the next steps for Task 3.3 and for the new versions of this deliverable.
The Living Arts: Valuing skills of Phulkari artisan of Punjab, India
Creators: name: Gupta, Anu
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Sense of Coherence (SOC) of Italian healthcare workers during the Covid-19 pandemic: analysis of associated factors
Creators: name: Piazza, Maria Francesca
name: Munarin, Ludovica
name: Ashong, Duke
name: Bellantonio, Giulia
name: Varnier, Arianna
name: Sanna, Francesca
name: Muzzin, Michela
name: Russo, Carmela
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Covid-19
COVID-19 pandemic
Health care workers
Italy
Covid-19 pandemic consequences

description: Introduction: The COVID-19 pandemic has posed significant challenges for healthcare workers worldwide, potentially affecting their sense of coherence (SOC) and overall well-being. This study aimed to identify factors associated with different levels of SOC among healthcare workers. Methods: A cross-sectional study was conducted among 628 healthcare workers. SOC scores were assessed using a standardized questionnaire, and data on demographic characteristics, length of service, geographic location, and pandemic-related experiences were collected. Statistical analyses were performed to identify associations between these factors and SOC. Results: Healthcare workers had a lower average SOC score (mean: 57.1) compared to the national average in Italy (mean: 60.3). Younger age and shorter length of service were associated with a higher risk of low SOC (p<0.0001). Healthcare workers in the northwestern regions of Italy had an increased risk of low SOC compared to their counterparts in the northeastern regions (p=0.0336). Adverse pandemic-related experiences and worsening social relationships were also associated with a higher risk of low SOC (p<0.0001). Conclusions: This study highlights the unique challenges and stressors faced by healthcare workers during the COVID-19 pandemic and their impact on SOC. Age, length of service, geographic location, and social were significant factors influencing SOC levels. Targeted interventions are needed to enhance SOC and well-being, particularly for younger and newly employed healthcare workers. Strategies promoting social connections, work-life balance, and psychological support services are crucial to support healthcare workers' resilience and coping abilities.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
title: Experimental investigation of high speed micro machining of H13 tool steel and titanium alloy 6-4
Creators: name: T. Hang Tuah Baharudin, B.
Publisher: name: University of Liverpool Repository
Year: 2023

description: High-accuracy miniaturized components are increasingly in demand for various industries such as aerospace, biomedical, electronics, environmental, communication and automotive, and this coupled with new developments of High Speed Machining (HSM) has led to the emergence of a strong and viable technology in High Speed Micro Machining. This technology is very important in bridging the macro-domain and the nano- and micro- domains for making functional miniaturized components. High speed Micro Machining is a specific technology where high spindle speeds, high performances cutting tools and high accuracy control systems are used. The understanding of this technology is still not well established and theories are still under development. A major implication of the High Speed Micro Machining process is the relatively high machining forces with respect to the cutting tool's size, which often cause low process reliability and high costs, due to frequent tool failures and short tool life. The aim of this investigation is to contribute towards a fundamental understanding of the effects of increased spindle speed in High Speed Micro Machining.
Knowledge and training of Italian students in Healthcare Settings on COVID-19 vaccines and vaccination strategies, one year after the immunization campaign
Creators: name: Bechini, Angela
name: Vannacci, Alfredo
name: Salvati, Cristina
name: Crescioli, Giada
name: Lombardi, Niccolò
name: Chiesi, Fabrizio
name: Shtylla, Jonida
name: Del Riccio, Marco
name: Bonanni, Paolo
name: Boccalini, Sara
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: medical education, elective training activities, HCWs, SARS-CoV-2 vaccine, public health
COVID-19 vaccines
Health Literacy
Medical Education

description: Abstract Introduction: COVID-19 vaccines represent an important opportunity for defeating the disease, as long as high vaccination acceptance rates are achieved. Healthcare workers (HCWs) have a relevant role in the promotion of immunization. The aim of the study is to assess the knowledge of medical and pharmaceutical area students regarding COVID-19 vaccination and the impact of a specific Elective Teaching Activity (ETA), one year after the immunization campaign in Italy. Methods: Students’ knowledge was tested with a questionnaire before and after attending the course. Descriptive statistical methods were used to analyse the results obtained. Student’s t-tests for paired data were used. Results: Overall, 387 students at the University of Florence attended the course and took the same test before and after the ETA on COVID-19 vaccines. Despite achieving satisfactory average scores in the pre-course test (26/32±4.0), all students were able to significantly enhance their final score (+17.1%; p<0.001), indicating that the ETA was highly effective in improving their knowledge of COVID-19 vaccination. Medical students demonstrated a better comprehension of the role of the medical specialist in public health in the COVID-19 vaccination campaign, while some uncertainties were revealed regarding the role of pharmacists. Conclusions: The results of this study confirm that specific training activities on vaccination are effective for implementing the knowledge of future health professionals.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
title: Identifying 'high performing' entrepreneurial oriented microenterprises -an empirical framework
Creators: name: Lahiri, Dhruba
Publisher: name: University of Liverpool Repository
Year: 2015

description: In the aftermath of the financial crisis of 2008, economies and governments across the world have progressively recognised the importance of 'technology' and 'entrepreneurship' as the driving forces for creation of economic value and wealth. In the context of microenterprises, firm level characteristics like the ability to absorb ‘technology’ (i.e. Absorptive Capacity) and to act ‘entrepreneurially’ (namely, Entrepreneurial Orientation) have become important measurements. This research presents a methodology that integrates the Entrepreneurial Orientation (EO) and Absorptive Capacity (ACAP) constructs to explain the performance of microenterprises and identify high performers. The performance of microenterprises has been measured in terms of their potential to create value or wealth. This research validates that a ‘forward looking’ measure of performance that measures the ‘potential value or wealth’ is more suitable than the conventional measure, which uses historical data. It also establishes that the EO and ACAP constructs can be successfully integrated to explain a large part of this value or wealth creating potential. This study covers 165 UK based microenterprises spread across different sectors and industries. Seventy (70) of these microenterprises have been labelled as ‘Entrepreneurial Oriented (EO)’ type enterprises as distinct and separate from the 95 Small Business Owners (SBO) types. The demarcation between the EO and SBO type has been justified and subsequently validated in this research. The results show that it is possible to demarcate between the EO and SBO type enterprises before their respective internal attributes (EO or SBO) are measured. This is particularly important since the two types of enterprises have different antecedents that drive their performance. As in previous studies, this research found Entrepreneurial Orientation (EO) to be a uni-dimensional concept. On the other hand, Absorptive Capacity (ACAP), applying the original definition of Cohen & Levinthal (1991) was found to comprise of three components. The predictive model used in this study based on Principal Component analysis (PCA) and Ordinal Regression was able to successfully identify a majority (81.81%) of the high performers. More importantly, none of the low and only one of the medium performers was wrongly identified as high performers. The development of a methodology to predict potentially high value-creating microenterprises has important ramifications for policymaking and economic development both in developed economies like the United Kingdom as well as peripheral and developing economies
Goedel's other legacy and the imperative of a self-reflective science
Creators: name: Basios, Vasileios
name: Bouratinos, Emilios
Publisher: name: arXiv
Year: 2014
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: The Goedelian approach is discussed as a prime example of a science towards the origins. While mere selfreferential objectification locks in to its own byproducts, self-releasing objectification informs the formation of objects at hand and their different levels of interconnection. Guided by the spirit of Goedel's work a self-reflective science can open the road where old tenets see only blocked paths. "This is, as it were, an analysis of the analysis itself, but if that is done it forms the fundamental of human science, as far as this kind of things is concerned." G. Leibniz, ('Methodus Nova ...', 1673)
description: 4 pages, no figures Conference: "Horizons of Ttuth: Goedel Centenary", Unicersity of Vienna 2006). appears as Kurt Goedel Society Collegium Logicum, vol. IX, pg. 1-5, 2006
Prevalence and Associated Factors of Depression, Anxiety, and Stress Among Academic Medicine Faculty in Kazakhstan: A Cross-sectional Study
Creators: name: Uristemova, Assem
name: Myssayev, Ayan
name: Meirmanov, Serik
name: Migina, Lyudmila
name: Pak, Laura
name: Baibussinova, Assel
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Psychological Distress
Depression
Anxiety
Stress
Medical Faculty
Public Health
Psychological Well-being
Occupational Health

description: Introduction: Psychological distress refers to a set of painful mental and physical symptoms of anxiety and depression, which often coexist and coincide with common somatic complaints and chronic conditions. In Kazakhstan, mental disorders are the second leading cause of years lived with disability. Currently, medical education in Kazakhstan is undergoing comprehensive reform, which creates an additional burden on faculty, fostering mental health concerns. Methods: A quantitative observational cross-sectional study was conducted in 6 large medical universities in Kazakhstan. Data were obtained from 715 faculty academics by using an online self-reported DASS-21. Statistical analysis was performed using the SPSS version 23.0. Bivariate and multivariate logistic regression analyses were applied to evaluate the relationship between predictor and outcome variables. Results: The total prevalence of depression, anxiety, and stress was 40.6%, 41.3%, and 53.0%, respectively. Younger age (p = 0.002), female gender (p = 0.001), being single (p = 0.044) or in a relationship (p = 0.001), having chronic diseases (p < 0.001), holding Master (p = 0.036) or PhD degree (p = 0.040), employment status (p = 0.034), and being involved in additional activities (p = 0.049) were significantly associated with different dimensions of distress. Conclusions: Nearly half of the study population reported symptoms of depression, anxiety, and stress. Due to the higher prevalence of psychological distress amongst academic medicine faculty, determined risk factors must be taken into consideration in developing policies for mental issues prevention.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
title: Characterising the role of anterior gradient protein 2 in cell adhesion and metastasis
Creators: name: Clarke, Christopher
Publisher: name: University of Liverpool Repository
Year: 2015

description: Anterior gradient protein 2 (AGR2) is overexpressed in many cancers, in particular those of the breast, ovary, prostate and pancreas. This overexpression tends to correlate with a poor disease prognosis for patients, probably as a result of increased incidence of metastases, and indeed, AGR2 has been shown to play a role in cell adhesion in different cell lines. Whilst AGR2 is a member of the protein disulphide isomerase (PDI) family of endoplasmic reticulum (ER) chaperones, there are also multiple reports of the secretion of AGR2 by cultured cells and the protein is also found in the serum and urine of cancer patients. AGR2 is a dimer, and the dimerisation interface is characterised here. A short, flexible region of the protein is also described, that seems to be involved in the regulation of the adhesion activity of AGR2. Through the use of stable cell lines expressing wild type and several mutant AGR2 proteins, it is shown here that wild-type AGR2 expression is associated with changes in cell adhesion and anchorage-independent cell growth, that are lost upon inhibition of protein dimerisation, mutation of the putative active site or a change in the sub-cellular localisation of the AGR2. Furthermore, the secretion of AGR2 has been confirmed through the discovery of a glycosylated, extracellular form of the protein. The expression of AGR2 is shown to be associated with a number of changes to the secreted proteome, with effects on both pro-adhesive and anti-adhesive proteins that may contribute to the role of AGR2 in cell adhesion. Overall, through combined biochemical, cell biology and mass spectrometry approaches, potential mechanisms whereby AGR2 might contribute to cell adhesion and metastasis are explored and discussed.
Epidemiology and genetic determinants of progressive deterioration of glycaemia in American Indians: the Strong Heart Family Study
Creators: name: Voruganti, V. S.
name: Haack, K.
name: Franceschini, N.
name: Fabsitz, R. R.
name: Lee, E. T.
name: North, K. E.
name: Almasy, L.
name: MacCluer, J. W.
name: Best, L. G.
name: Göring, H. H. H.
name: Meigs, J. B.
name: Pankow, J. S.
name: Cole, S. A.
name: Laston, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Type 2 diabetes is a chronic, heterogeneous disease and a major risk factor for cardiovascular diseases. The underlying mechanisms leading to progression to type 2 diabetes are not fully understood and genetic tools may help to identify important pathways of glycaemic deterioration.
Status of the Utilization of Preventive Care Services and its Affecting Socio-Demographic Factors among Iranian Elderly
Creators: name: Mohamadi Khanghah, Rozita
name: Besharati, Fereshteh
name: Pourghane, Parand
name: Gholami-Chaboki, Bahareh
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Preventive Measures
Aged
Demographic Factors
Preventive Care

description: Objective: The growing population of the elderly, the rising costs of medical care and the low use of preventive services are three factors that highlight the importance of using preventive health care services in the Iranian population. This study aimed to determine the status of the use of preventive care services and its affecting socio-demographic factors in the elderly referring to health centers. Methods: In this descriptive-analytical study, a number of 160 elderly people referring to health centers in East Guilan, Iran were selected by multi-stage cluster sampling. Utilization of preventive care services and socio-demographic factors were assessed using a questionnaire. Results: The highest and the lowest utilization rates of preventive care services among study participants were related to the blood pressure control (96.9%) and colonoscopy (17.5%), respectively. Multivariate analysis showed that only income had a significant association with performing fasting blood sugar test (P=0.004), blood cholesterol test (P=0.004), and blood pressure control test (P=0.013). Also, the associations between having an underlying disease and performing fasting blood sugar test (P=0.032) and blood pressure control test (P=0.002), the association between gender and performing the bone mineral density test (P<0.001), and the association between occupation and performing Pap-smear test (P=0.011), were statistically significant. Conclusion: The utilization rates of screening tests for most cancers, including gastrointestinal cancers, were low. Since, there were a significant association between income, disease, gender and occupation with the utilization of some preventive care services, considering them in health centers’ preventive care program design might be useful.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
Animation, Fashion and Sustainability
Creators: name: McKelvey, Kathryn
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Short paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Use of medicines to alleviate negative emotional states among adolescents attending Special Education Centres
Creators: name: Pisarska, Agnieszka
name: Ostaszewski, Krzysztof
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: medicine use
negative emotional states
risk/protective factors
youth at risk
special education centres
medicine and prevention
young people
risk factors
protective factors

description: Introduction: Substantial research evidence indicates that adolescents commonly use a variety of pharmaceuticals. Studies in this area carried out so far in Poland have focused on youth attending mainstream schools. However, there is a lack of research covering adolescents residing in special education centres (SEC). The purpose of the study was to assess the prevalence of medicine use for negative emotional states (nervousness, difficulties in falling asleep, and depressive mood), and to identify factors associated with the use of the aforementioned medications by SEC youth. Material and methods: The study was conducted in 2018 on a random nationwide sample of SEC adolescents aged 12-19 (N=1730). The logistic regression analyses included sociodemographic variables, as well as factors related to the participant’s individual characteristics and to their social environment. Results: Medicine use for negative emotional states was confirmed by about 24% - 30% of respondents. The prevalence of these medicine use among SEC youth was significantly higher than among adolescents from mainstream schools. The individual risk factors associated with medicine use were gender (female), current mental and somatic health problems, past suicide attempts and psychoactive substances use while self-control turned out to be protective factor. Among factors related to the respondents' social environment, positive relationships with peers were significant protective factor. Conclusions: Preventive measures aimed at SEC youth should be focused on improving positive relationships with peers and developing self-control. Educational programs for youth, their parents and SEC staff to develop knowledge and skills regarding safe medicines intake would also be useful.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
title: Identification of deubiquitinating enzymes regulating the HGF-mediated cell scattering
Creators: name: Buus, Richard
Publisher: name: University of Liverpool Repository
Year: 2023

description: Protein ubiquitinatlon is a dynamic and reversible post-translational modification implicated In the regulation of a number of cell signalling pathways. Nevertheless, its involvement in the Hepatocyte Growth Factor (HGF)-mediated cell scattering has not been studied before. Here, I tested the hypothesis that ubiquitin signalling regulates HGF-mediated scattering. In the first part of this project, I carried out an HGF-dependent scattering screen in A549 cells using an sIRNA library targeting the deubiquitinating enzymes (DUBs). My screen of 83 DUB genes identified twelve potential regulators that inhibited scattering upon knockdown, Subsequently, I performed a series of experiments to characterise the candidate DUBs identified in the screen. I associated distinct cell morphologies with the depletion of different DUBs and also, where possible I correlated the level of DUBs with the HGF-mediated motility response.