title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐ°Ð½Ð¾Ð·Ð°Ð¶Ð¸Ð²Ð»ÑÑÑÐµÐ³Ð¾ Ð±Ð¸Ð¾Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¾Ð² Ð³ÑÐ°Ð½Ð¸Ð´Ð¸Ð½Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Development of a woundâhealing biopreparation based on guanidine copolymers
Creators: name: Ð¡Ð²ÐµÑÐ»Ð¾Ð², ÐÐ°Ð½Ð¸Ð¸Ð»
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: ÐÐ¸Ð¾ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ñ
Ð»ÐµÐºÐ°ÑÑÑÐ²ÐµÐ½Ð½ÑÐµ ÑÑÐµÐ´ÑÑÐ²Ð°
Ð±Ð¸Ð¾ÑÐ¸Ð´Ð½ÑÐµ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð°
ÑÐ¾ÐºÑÐ¸ÐºÐ¾Ð»Ð¾Ð³Ð¸Ñ
ÑÑÐ°Ð¼Ð¼Ñ Ð¼Ð¸ÐºÑÐ¾Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼Ð¾Ð²
ÑÐ°Ð½Ð¾Ð·Ð°Ð¶Ð¸Ð²Ð»ÐµÐ½Ð¸Ðµ
medicines
biocidal properties
toxicology
strains of microorganisms
wound healing

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±ÑÐ»Ð° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ° Ð¡ÐÐ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¾Ð² Ð³ÑÐ°Ð½Ð¸Ð´Ð¸Ð½Ð° - Ð¿Ð¾Ð»Ð¸Ð³ÐµÐºÑÐ¾Ð¼ÐµÑÐ¸Ð»ÐµÐ½Ð³ÑÐ°Ð½Ð¸Ð´Ð¸Ð½ Ð³Ð¸Ð´ÑÐ¾ÑÐ»Ð¾ÑÐ¸Ð´Ð° (ÐÐÐÐ-ÐÐ¥) Ð´Ð»Ñ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ ÐµÐ³Ð¾ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¸ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ½Ð¾Ð³Ð¾ Ð±Ð¸Ð¾Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¡ÐÐ Ð½Ð° ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÐµÐ³Ð¾ ÑÐ°Ð½Ð¾Ð·Ð°Ð¶Ð¸Ð²Ð»ÐµÐ½Ð¸Ñ. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: 1. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¾Ð±Ð·Ð¾ÑÐ° Ð»Ð¸ÑÐµÑÐ°ÑÑÑÑ; 2. ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð±Ð¸Ð¾ÑÐ¸Ð´Ð½ÑÑ ÑÐ²Ð¾Ð¹ÑÑÐ² Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¾Ð² Ð³ÑÐ°Ð½Ð¸Ð´Ð¸Ð½Ð° (Ð¡ÐÐ); 3. ÐÐ·ÑÑÐµÐ½Ð¸Ðµ ÑÐ¾ÐºÑÐ¸ÐºÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ²Ð¾Ð¹ÑÑÐ² Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¾Ð² Ð³ÑÐ°Ð½Ð¸Ð´Ð¸Ð½Ð° (Ð¡ÐÐ); 4. ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ°Ð½Ð¾Ð·Ð°Ð¶Ð¸Ð²Ð»ÑÑÑÐ¸Ñ ÑÐ²Ð¾Ð¹ÑÑÐ² Ð±Ð¸Ð¾Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¾Ð² Ð³ÑÐ°Ð½Ð¸Ð´Ð¸Ð½Ð° (Ð¡ÐÐ); 5. ÐÐ½Ð°Ð»Ð¸Ð· Ð¿Ð¾ÑÑÐµÐ±Ð¸ÑÐµÐ»ÐµÐ¹ Ð¸ ÐºÐ¾Ð½ÐºÑÑÐµÐ½ÑÐ¾Ð² Ð½Ð° ÑÑÐ½ÐºÐµ Ð»ÐµÐºÐ°ÑÑÑÐ²ÐµÐ½Ð½ÑÑ ÑÑÐµÐ´ÑÑÐ² Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ Ð½Ð°ÑÐµÐ³Ð¾ Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ°. Ð Ð°Ð±Ð¾ÑÐ° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð½Ð° Ð±Ð°Ð·Ðµ Ð¤ÐÐ£Ð ÐÐÐÐ­Ð Ð¸Ð¼. ÐÐ°ÑÑÐµÑÐ° Ð¸ ÐÐÐ Â«Ð¡Ð¾ÑÑâÐÑÐ¾ÑÐµÐºÑÐ¾ÑÂ», Ð³Ð´Ðµ Ð±ÑÐ»Ð¸ Ð¸Ð·ÑÑÐµÐ½Ñ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð°, Ð¿Ð¾ ÐºÐ¾ÑÐ¾ÑÑÐ¼ Ð¿ÑÐ¾Ð²ÐµÑÑÑÑ Ð´ÐµÐ·Ð¸Ð½ÑÐµÐºÑÐ°Ð½ÑÑ Ð¸ Ð¿Ð¾Ð´Ð¾Ð±ÑÐ°Ð½Ñ Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿ÑÐ¸ÑÐ°Ð´ÐºÐ¸ Ð´Ð»Ñ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ°. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð±ÑÐ»Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ñ Ð±Ð¸Ð¾ÑÐ¸Ð´Ð½Ð°Ñ Ð¸ ÑÐ¾ÐºÑÐ¸ÐºÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ°Ñ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¡ÐÐ, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÐ°Ð½Ð¾Ð·Ð°Ð¶Ð¸Ð²Ð»ÐµÐ½Ð¸Ñ Ð±Ð¸Ð¾Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÐ° Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¡ÐÐ. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ð´Ð°Ð½Ð½ÑÑ Ð±ÑÐ» ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ Ð±Ð¸Ð¾Ð¿ÑÐµÐ¿Ð°ÑÐ°Ñ Ñ ÑÑÑÐµÐºÑÐ¾Ð¼ ÑÐ°Ð½Ð¾Ð·Ð°Ð¶Ð¸Ð²Ð»ÐµÐ½Ð¸Ñ. ÐÑÐ¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ð¸ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±Ð·Ð¾ÑÐ° Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð»Ð¸ÑÑ ÑÐ»ÐµÐ´ÑÑÑÐ¸Ðµ Ð±Ð°Ð·Ñ Ð´Ð°Ð½Ð½ÑÑ: eLIBRARY.RU, Elsevier ScienceDirect, Scopus, PubMed, NCBI. Ð¡ÑÐ°ÑÐ¸ÑÑÐ¸ÑÐµÑÐºÑÑ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÑ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½ÑÑ Ð´Ð°Ð½Ð½ÑÑ Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÐ»Ð¸ Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ð³Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Microsoft Excel.
description: This work was devoted to the study of an CPG preparation based on guanidine copolymers - polyhexomethyleneguanidine hydrochloride (PHMG-HC) to determine its effectiveness and safety, and a study of a complex biological preparation based on CPG for the effectiveness of its wound healing was conducted. Tasks that were solved during the research: 1. Conducting an analytical review of the literature; 2. Investigation of the biocidal properties of the drug based on guanidine copolymers (CPG); 3. Study of the toxicological properties of the drug based on guanidine copolymers (CPG); 4. Investigation of wound healing properties of a biopreparation based on guanidine copolymers (CPG); 5. Analysis of consumers and competitors in the market of medicines using the example of our drug. The work was carried out on the basis SaintâPetersburg Pasteur Institute and Â«Soft ProtectorÂ» LLC, where the properties by which disinfectants are tested were studied and biological additives were selected to create a complex preparation. As a result, the biocidal and toxicological activity of CPG, as well as the effectiveness of wound healing of an CPGâbased biological product, were investigated. Based on the data obtained, a biopreparation with the effect of wound healing was developed. The following databases were used to perform the literature review: eLibrary.RU, Elsevier ScienceDirect, Scopus, PubMed, NCBI. Statistical processing of experimental data was carried out using Microsoft Excel software.