cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Stress transfer and Quaternary faulting in the northern Alpine foreland
Creators: name: Mader, S.
name: Reicherter, K.
name: Ritter, J.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Quaternary faulting
subject: Northern Alpine foreland
subject: 500 Natural sciences and mathematics::550 Earth sciences::550 Earth sciences

description: Within the SPP Mountain Building Processes in Four Dimensions (MB-4D) we studied postglacial and present seismic rupturing in the northern Alpine Foreland to better understand the impact and forces of mountain building. We started a seismological field experiment to densify the permanent monitoring networks and the AlpArray Seismic Network. The later was also supported as well as its predecessor UNIBRA (Hetényi et al., 2018; Schlömer et al., 2022). Our StressTransfer network consisted of five recording stations in the Upper Rhine Graben, five in the Molasse Basin and five around the Albstadt Shear Zone (Mader et al., 2021a). The latter are still operating due to the increased seismicity during the last years below the western Swabian Alb. We determined local minimum 1-D seismic velocity models to relocate known events in the study regions (Mader et al., 2021b). Waveform cross-correlation was done to detect hitherto unknown events and recover earthquake sequences around the Albstadt Shear Zone (Mader et al., subm.). To determine fault planes and rupture mechanisms we used relative event locations (hypoDD) and FOCMEC for fault plane solutions. For the Albstadt Shear Zone (ASZ), an NNE–SSW striking left-lateral strike-slip rupture zone, we determined a direction of the maximum horizontal stress (SHmax) of 140°–149°. Down to ca. 7–8 km depth, SHmax is bigger than SV (vertical stress); below this depth, SV is the main stress component. Beneath the shallow Hohenzollerngraben (ca. 2-3 km depth), which is nearly perpendicular to the ASZ, we found an NW-SE striking dextral strike-slip fault zone with very weak micro-seismicity in 11-15 km depth (Figure 1). This zone is possibly a reactivated old upper-crustal tectonic structure. At the interception of the ASZ and the NW-SE striking fault zone we observe NNW-SSE striking sinistral strike-slip and normal faulting micro-earthquakes which belong to a heterogeneous deformation zone with complex faulting. In Figure 1 we summarize our current model for the ASZ and its surroundings. The detection of many micro-earthquakes and the related active faults was only possible with the help of the additional temporal recording stations in the region and the studies of a PhD student (S.M.). We thank the DFG for funding our project and the State Earthquake Service Baden-Württemberg in Freiburg for providing data (Az. 4784//18_3303).
title: Modelling transient stresses in dynamically loaded elastic solids using the Lattice Boltzmann Method
Creators: name: Faust, Erik
name: Steinmetz, Felix
name: Schlüter, Alexander
name: Müller, Henning
name: Müller, Ralf
Publisher: name: Wiley‐VCH
Year: 2023

description: In solids subjected to transient loading, inertial effects and S‐ or P‐wave superposition can give rise to stresses which significantly exceed those predicted by quasi‐static models. It pays to accurately predict such stresses – and the failures induced by them – in fields from mining to automotive safety and biomechanics. This, however, requires costly simulations with fine spatial and temporal resolutions. The Lattice Boltzmann Method (LBM) can be used as an explicit numerical solver for certain appropriately formulated conservation laws [1]. It encodes information about the field variables to be simulated in distribution functions, which are modified locally and propagated across a regular lattice. As the LBM lends itself to finely discretised simulations and is easy to parallelise [2, p.55], it is an intriguing candidate as a solver for dynamic continuum problems. Recently, Murthy et al. [3] and Escande et al. [4] adopted LBM algorithms to model isotropic, linear elastic solids. We extended these algorithms using local boundary rules that allow us to model arbitrary‐valued Dirichlet and Neumann boundaries. Here, we illustrate applications of the LBM for solids and the proposed additions by way of a simple numerical example – a glass pane subject to a sudden impact load.
Essays on Migration and Gender
Creators: name: Croc�, Clementina
Publisher: name: Universit� degli studi di Trento
Year: 2021

description: This thesis investigates the interdependence between migration and gender dynamics, with a focus on low- and middle-income countries. The first chapter concerns intra-household bargaining and migration decision-making: considering that the decision to migrate is likely to be made within the family, the bargaining powers of household members may shape the result of the decision-making process. Given that there is evidence of women?s altruistic behaviours towards their children, I investigate how women?s bargaining power affects the decisions about the individual migrations of their young offspring, who may benefit from the change in location. A collective model of migration decision-making and an empirical analysis regarding the context of Mexico are presented. This analysis sheds the light on how empowerment may be beneficial not only to women themselves but also to their children, and suggests that policies intending to improve women?s position within the household and the whole society should also acknowledge these positive spillover effects. The second chapter regards the uncertainty over health status and the gendered determinants of migration. While several studies show a relationship between migration and health, migration selection in terms of health conditions is relatively under-investigated, as regards the context of Sub-Saharan African countries. Using panel data from a survey on young women and men living in Malawi, I assess the impact of randomised HIV testing on long- and short-term migrations, and I find that becoming certain of being HIV-negative affects the probability of both types of movements, only for women. This impact evaluation indicates that HIV testing may have gender-specific unintended consequences, which should be considered. Finally, the third chapter evaluates the impact of a randomised intervention, aiming to promote child development through improvements in parenting skills, on the empowerment of women in Bangladesh. Results show that the programme increases women?s autonomy and reduces their exclusion from decision-making processes: these effects do not concern only child-related decisions ? consistent with the type of training that women in the treatment group receive ? but also decisions about the allocation of resources. The empowerment effect regards only women whose partner has never migrated before the baseline, thus suggesting the existence of a relationship between women?s decision-making power and men?s migration ? as found in previous studies.
title: Blocking the chain
title: Industrial food chain concentration, Big Data platforms and food sovereignty solutions
titleType: Subtitle
Creators: name: Mooney, Pat
Publisher: name: Freie Universität Berlin
Year: 2018
Subjects: subject: Big Data technologies
subject: Big Data
subject: Landwirtschaft
subject: Nahrungsmittelindustrie
subject: agriculture
subject: food production
subject: digitalisation
subject: Digitalisierung
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::300 Sozialwissenschaften
subject: 300 Sozialwissenschaften::320 Politikwissenschaft::320 Politikwissenschaft

description: Smart Farming, Drohnen, per Satellit gesteuerte Traktoren, die Nutzung von Klima- und Wetterdaten durch Big Data oder die Anwendung von synthetischer Biologie: Ist die Digitalisierung von Landwirtschaft und Ernährung tatsächlich das neue Wundermittel, um Hungerkrisen zu beenden, den Verlust an Biodiversität zu stoppen oder den Klimawandel aufzuhalten? Im Policy Paper „Breaking the Chain – Konzernmacht und Big-Data-Plattformen im globalen Ernährungssystem“ setzt sich Pat Mooney, Träger des Alternativen Nobelpreises, kritisch mit der Digitalisierung in der Landwirtschaft auseinander. Er analysiert, wer die zentralen Akteure im Digitalisierungsgeschäft sind und beleuchtet die Bedeutung der Digitalisierung für kleinbäuerliche Erzeuger*innen und Arbeit*innen in Landwirtschaft und Nahrungsmittelindustrie weltweit. Neue Technologien versprechen Effizienzsteigerungen und Nachhaltigkeit bei der Erzeugung. Dabei geht es im Kern um das massenhafte Sammeln und Auswerten von Hof-, Anbau- und Verbraucher*innendaten. Agrarkonzerne wie Bayer und Deere, aber auch Internetkonzerne wie Amazon und Google sind längst dabei, sich die Hoheit über die Digitalisierung der Landwirtschaft anzueignen. Durch Fusionsprozesse konsolidieren sie ihre Dominanz nicht nur in einem Sektor, sondern vertikal entlang mehrerer Schnittstellen der Lebensmittelkette. Ihre Bemühungen werden durch politische Entscheidungsträger*innen in Deutschland und anderswo unterstützt, die vor allem die Vorteile der Digitalisierung betonen und Investitionshemmnisse aus dem Weg räumen wollen. Mooney zeigt die problematischen Auswirkungen dieser Tendenzen ebenso wie die Grenzen der Digitalisierung auf und diskutiert, inwieweit die Digitalisierung für den Umbau hin zu einer sozial-ökologisch gerechten Landwirtschaft genutzt werden könnte. Die Studie „Breaking the Chain – Konzernmacht und Big-Data-Plattformen im globalen Ernährungssystem“ ist eine gemeinsame Publikation von ETC Group, GLOCON, INKOTA und der Rosa-Luxemburg-Stiftung.
Strong out-of-plane magnetic anisotropy of Fe adatoms on Bi$_2$Te$_3$
Creators: name: Eelbo, T.
name: Waśniowska, M.
name: Sikora, M.
name: Dobrzański, M.
name: Kozłowski, A.
name: Pulkin, A.
name: Autès, G.
name: Miotkowski, I.
name: Yazyev, O. V.
name: Wiesendanger, R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The electronic and magnetic properties of individual Fe atoms adsorbed on the surface of the topological insulator Bi$_2$Te$_3$(111) are investigated. Scanning tunneling microscopy and spectroscopy prove the existence of two distinct types of Fe species, while our first-principles calculations assign them to Fe adatoms in the hcp and fcc hollow sites. The combination of x-ray magnetic circular dichroism measurements and angular dependent magnetization curves reveals out-of-plane anisotropies for both species with anisotropy constants of $K_{\text{fcc}} = (10 \pm 4)$ meV/atom and $K_{\text{hcp}} = (8 \pm 4)$ meV/atom. These values are well in line with the results of calculations.
description: 6 pages, 3 figures
Field Evaluation of a Rising Plate Meter to Estimate Herbage Mass in Austrian Pastures
Creators: name: Chapa, Jose Maria
name: Pichlbauer, Barbara
name: Bobal, Martin
name: Guse, Christian
name: Drillich, Marc
name: Iwersen, Michael
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: rising plate meter
subject: herbage mass
subject: grazing management
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Pasture management is an important topic for dairy farms with grazing systems. Herbage mass (HM) is a key measure, and estimations of HM content in pastures allow for informed decisions in pasture management. A common method of estimating the HM content in pastures requires manually collected grass samples, which are subjected to laboratory analysis to determine the dry matter (DM) content. However, in recent years, new methods have emerged that generate digital data and aim to expedite, facilitate and improve the measurement of HM. This study aimed to evaluate the accuracy of a rising plate meter (RPM) tool in a practical setting to estimate HM in Austrian pastures. With this study, we also attempted to answer whether the tool is ready for use by farmers with its default settings. This study was conducted on the teaching and research farm of the University of Veterinary Medicine in Vienna, Austria. Data were collected from May to October 2021 in five different pastures. To evaluate the accuracy of the RPM tool, grass samples were collected and dried in an oven to extract their DM and calculate the HM. The HM obtained from the grass samples was used as the gold standard for this study. In total, 3796 RPM measurements and 203 grass samples yielding 49 measurement points were used for the evaluation of the RPM tool. Despite the differences in pasture composition, the averaged HM from the RPM tool showed a strong correlation with the gold standard (R2 = 0.73, rp = 0.86, RMSE = 517.86, CV = 33.67%). However, the results may not be good enough to justify the use of the tool, because simulations in economic studies suggest that the error of prediction should be lower than 15%. Furthermore, in some pastures, the RPM obtained poor results, indicating an additional need for pasture-specific calibrations, which complicates the use of the RPM tool.
การนำแนวคิดขีดความสามารถเป็นฐานในการจัดการเรียนการสอน
Creators: name: พีระนันท์ นัมคณิสรณ์
Publisher: name: คณะครุศาสตร์ มหาวิทยาลัยราชภัฏพิบูลสงคราม
Year: 2020
Subjects: Instruction Management
Competencies of the Learner
Learner's Development

description: วารสารครุพิบูล, 7, 1, 1-12
การพัฒนาผลสัมฤทธิ์ทางการเรียน การคิดแก้ปัญหา และพฤติกรรมเชิงจริยธรรมด้านความรับผิดชอบ ของนักเรียนชั้นประถมศึกษาปีที่ 6 ที่ได้รับการจัดกิจกรรมการเรียนรู้แบบสืบเสาะหาความรู้ร่วมกับประเด็นวิทยาศาสตร์กับสังคม
Creators: name: ลักคณา มหันต์
name: ประสาท เนืองเฉลิม
Publisher: name: คณะครุศาสตร์ มหาวิทยาลัยราชภัฏพิบูลสงคราม
Year: 2020
Subjects: วิทยาศาสตร์กับสังคม
สืบเสาะหาความรู้
การคิดแก้ปัญหา
พฤติกรรมเชิงจริยธรรม
ผลสัมฤทธิ์ทางการเรียน
วิจัยปฏิบัติการ

description: วารสารครุพิบูล, 7, 1, 13-25
Lignocellulosic materials coated with Trichoderma atroviride SC1 increase its persistency in the soil and impact soil microbiota
Creators: name: Chammem, Hamza
Publisher: name: Universit� degli studi di Trento
Year: 2022

description: Trichoderma atroviride SC1 (SC1) was isolated from hazelnut wood and it is effective in the biocontrol of soil-borne pathogens. However, its effectiveness decreases as its population declines in the soil over time. To improve its persistency in the soil, lignocellulosic materials (wood pellets) were tested to be used as carriers to sustain the population of SC1 and facilitate its incorporation into the soil. A method was developed to coat wood pellets of fir, beech, and chestnut with a conidial suspension to reach a preset concentration (i.e. 10^4, 10^5, and 10^6 cfu/ g of wood). The growth of SC1 on each type of wood was compared. Chestnut pellets were excluded from further experiments because they had low counts of colony-forming units (cfu) of SC1. Beech pellets were preferred over fir pellets for showing more suitable physicochemical characteristics for soil application. In addition, for the same wood type, increased initial coating concentrations did not impact the final colony counts of SC1 and no significant difference was observed between the counts of 10^4, 10^5, and 10^6 cfu/g of wood at the end of the experiment. The addition of small quantities of nitrogen increased the final cfu on all types of wood pellets. The growth of SC1 on beech pellets was then tested by adding cheap nitrogen sources namely, soy flour, soy protein isolates, and proteins that originated from animal wastes. The best results were obtained with soy protein isolates (1 g/L) and the population of SC1 reached 10^9 cfu/ g of beech wood. Finally, this carrier of coated beech pellets with soy protein isolates was tested in the soil under controlled conditions, in an experimental greenhouse at 25�C and 60% of soil humidity. The pellets were coated to reach a final concentration of 5�10^5 cfu/ g of beech and 10 g of beech coated pellets were mixed with 1 kg of soil in plastic pots to reach the final concentration of 5�10^3 cfu/ g of soil. The carrier increased the bacterial richness and diversity of the soil and decreased the fungal ones. The total Trichoderma population persisted in the first month and then declined after three months with competition from other bacteria such as Massilia spp. and fungi such as Stachybotrys spp. and Mortierella spp.
PARTHENOS Leitfaden zur "FAIRifizierung" des Datenmanagements und der Ermöglichung der Nachnutzung von Daten
Creators: name: PARTHENOS
name: Hollander, Hella
name: Morselli, Francesca
name: Uiterwaal, Frank
name: Admiraal, Femmy
name: Trippel, Thorsten
name: Di Giorgio, Sara
Publisher: name: Zenodo
Year: 2019
Subjects: Guidelines
FAIR Prinzipien
Leitfaden
FAIRifizierung
Daten Management
Daten Nachnutzung
FAIR Principles
Data Management
Data Reuse

description: A comprehensive set of PARTHENOS Guidelines to FAIRify data management and make data reusable is focusing on the topic of common policies. This compact guide offers twenty guidelines to align the efforts of data producers, data archivists and data users in humanities and social sciences to make research data as reusable as possible based upon the FAIR Principles. Each guideline has recommendations for both researchers and archives as it is recognised that different priorities may apply to each case. The guidelines result from the work of over fifty PARTHENOS project members. They were responsible for investigating commonalities in the implementation of policies and strategies for research data management and used results from desk research, questionnaires and interviews with selected experts to gather around one hundred current data management policies (including guides for preferred formats, data review policies and best practices, both formal as well as tacit). Translation of "PARTHENOS Guidelines to FAIRify data management and make data reusable" (https://doi.org/10.5281/zenodo.2668479) into German by Laura Rothfritz, Claus Spiecker. Further versions of the guidelines are available in the following languages: Czech: "ZÁSADY zajištení FAIRové správy a využitelnosti dat" (https://doi.org/10.5281/zenodo.3946100) English: "PARTHENOS Guidelines to FAIRify data management and make data reusable" (https://doi.org/10.5281/zenodo.3368858) French: "PARTHENOS Recommandations pour FAIRiser vos données" (https://doi.org/10.5281/zenodo.3463521) Greek: "PARTHENOS Οδηγίες για την εφαρμογή των αρχών FAIR στη διαχείριση και επανάχρηση δεδομένων" (https://doi.org/10.5281/zenodo.3363386) Hungarian: "PARTHENOS A tudományos adatok újrafelhasználhatóságának és FAIR kezelésének irányelveii" (https://doi.org/10.5281/zenodo.3363355) Italian: "PARTHENOS Linee guida per l’applicazione dei principi FAIR alla gestione e al riuso dei dati" (https://doi.org/10.5281/zenodo.3363243) Portuguese: "Diretrizes para aplicação dos princípios FAIR à gestão e reutilização de dados" (https://doi.org/10.5281/zenodo.3937183) Turkish: "Veri Yönetimi ve verinin yeniden kullanımı için FAIR Prensipleri Rehberi" (https://doi.org/10.5281/zenodo.3937149)
description: Übersetzung: Laura Rothfritz, Claus Spiecker
Bioisosteric replacements of tyrosine kinases inhibitors to make potent and safe chemotherapy against malignant cells
Creators: name: Irfan, Navabshan
name: Balasubramaniyan, Sakthivel
name: Ali, Davoodbasha Mubarak
name: Puratchikody, Ayarivan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry

description: The liver function test is an imperative element in chemotherapy management due to the idiosyncratic reaction of chemotherapy drugs. This study primly aimed to replace the toxic fragments of known protein tyrosine kinases inhibitors (PTKi) to develop safe and effective chemotherapy. All the current PTKi’s were docked with the tyrosine kinases and metabolic enzymes to study the affinities on the target. It resulted from most of the PTKi’s found higher affinity and efficacy with metabolic enzymes lead the hepatic cells damage. To overcome this limitation of PTKi’s, a bioisosteric replacement strategy was achieved and conceptual analogs were designed. Specifically, the Generated pose of the Axitinib molecule showed that axitinib fragments C = C-, -C = O and NH2 produced clashes with active site residues of tyrosine kinases protein and good affinity with metabolic enzyme primes to the liver toxicity. The above said fragments were replaced with various bioisosteric groups and efficacy was measured. The resulting molecule shows improved affinity with tyrosine kinases enzyme and less interactions with metabolic enzyme were imminent molecule for the treatment of malignant cells with outside effects. Communicated by Ramaswamy H. Sarma
A 77-118 GHz Resonance-free Septum Polarizer
Creators: name: Chen, Yen-Lin
name: Chiueh, Tzihong
name: Teng, Hsiao-Feng
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Measurements of the polarized radiation often reveal specific physical properties of emission sources, such as strengths and orientations of magnetic fields offered by synchrotron radiation and Zeeman line emission, and the electron density distribution by free-free emission. Polarization-capable, millimeter/sub-millimeter telescopes are normally equipped with either septum polarizers or ortho-mode transducers (OMT) for the detection of polarized radiation. While the septum polarizer is traditionally conceived to be limited to a significantly narrower bandwidth than the OMT, it does possess advantageous features for astronomical polarization measurements unparalleled by the OMT. Challenging the conventional bandwidth limit, we design an extremely wideband circular waveguide septum polarizer, covering $42\%$ bandwidth, from 77 GHz to 118 GHz, without any undesired resonance. Stokes parameters constructed from the measured data in between 77 GHz and 115 GHz show that the leakage from $I$ to $Q$ and $U$ is below $\pm 2\%$ and the $Q-U$ mutual leakage below $\pm 1\%$. Such a performance is comparable to other modern polarizers, but the bandwidth of this polarizer can be at least twice as wide. This extremely wide-band design removes the major weakness of the septum polarizer and opens up a new window for future astronomical polarization measurements.
ผลสัมฤทธิ์ทางการเรียนวิชาประวัติศาสตร์ โดยใช้รูปแบบการเรียนแบบร่วมมือ เทคนิค STAD ร่วมกับวิธีการทางประวัติศาสตร์ของนักเรียนชั้นประถมศึกษาปีที่ 6
Creators: name: น้ำพลอย โพธิ์ขวัญ
name: ศิรประภา พฤทธิกุล
name: ปริญญา ทองสอน
Publisher: name: คณะครุศาสตร์ มหาวิทยาลัยราชภัฏพิบูลสงคราม
Year: 2020
Subjects: COOPERATIVE LEARNING
STAD TECHNIQUE
HISTORIC METHODOLOGY
ACHIEVEMENT OF HISTORY
ATTITUDE TOWARDS LEARNING HISTORY

description: วารสารครุพิบูล, 7, 1, 26-36
A structural characterisation of human heterotopic bone
Creators: name: Wiles, Crispin Charles Raymond
Publisher: name: Imperial College London
Year: 2019

description: Heterotopic ossification (HO) is the formation of new extra-skeletal osseous tissue. It is a common outcome following trauma, affecting up to 91% of blast-related amputees. However, the pathogenesis of HO remains poorly understood and there has been little investigation of the heterotopic bone which develops. The main objective of this thesis was to perform a multiscale characterisation of the structure of human heterotopic bone formed following trauma, for systematic and quantitative comparison with orthotopic bone. This was achieved using several analytical techniques. At microscale, µCT imaging was employed for 3-D visualisation and to perform digital histomorphometry and topological analysis on trabecular structure and osteocyte lacunae. At nanoscale, scanning wide- and small-angle X-ray scattering techniques using a synchrotron source were used to measure and map variations in the structural organisation of collagen fibrils and mineral crystals, supplemented by microscopic methods permitting direct visualisation of the collagen fibrillar organisation and mineral crystals. The data collected reveal that at microscale, heterotopic bone broadly resembles orthotopic bone tissue. At nanoscale, it undergoes a maturation process similar to that of fracture callus; and by around 50 – 100 weeks after injury it structurally resembles adult orthotopic bone. These similarities extend from the size and organisation of the nanoscale components including mineral crystals and collagen fibrils, to a common topological organisation of the trabecular bone, and the presence of a cortical shell. However, greater nanostructural heterogeneity was also observed. These observations provide support for the interpretation that heterotopic bone is essentially normal osseous tissue, where the structural abnormalities observed relate to the abnormal tissue environment rather than intrinsic structural differences relative to orthotopic bone. These findings extend prior understanding of heterotopic bone structure and have a range of implications which include providing indirect support for attempts to model HO in silico.
Design optimization of passively mode-locked semiconductor lasers with intracavity grating spectral filters
Creators: name: O'Callaghan, Finbarr
name: Bitauld, David
name: O'Brien, Stephen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We consider design optimization of passively mode-locked two-section semiconductor lasers that incorporate intracavity grating spectral filters. Our goal is to develop a method for finding the optimal wavelength location for the filter in order to maximize the region of stable mode-locking as a function of drive current and reverse bias in the absorber section. In order to account for material dispersion in the two sections of the laser, we use analytic approximations for the gain and absorption as a function of carrier density and frequency. Fits to measured gain and absorption curves then provide inputs for numerical simulations based on a large signal accurate delay-differential model of the mode-locked laser. We show how a unique set of model parameters for each value of the drive current and reverse bias voltage can be selected based on the variation of the net gain along branches of steady-state solutions of the model. We demonstrate the validity of this approach by demonstrating qualitative agreement between numerical simulations and the measured current-voltage phase-space of a two-section Fabry-Perot laser. We then show how to adapt this method to determine an optimum location for the spectral filter in a notional device with the same material composition, based on the targeted locking range, and accounting for the modal selectivity of the filter.
description: 12 pages, 9 figures
Design optimisation of all-steel rectangular honeycomb core sandwich panels
Creators: name: Pinho Santos, Luis Fernando
Publisher: name: Imperial College London
Year: 2019

description: This work focuses on all-steel sandwich construction and its application for deck systems in offshore topside structures. Conventional deck systems are heavy, extremely difficult to assemble and lack the functional flexibility against load relocation, impacting the project time schedule and completion. The main objective is to develop design and optimisation methods for sandwich panels as a better solution than the traditional one in terms of weight, construction time, life span, safety, assembly process and overall cost. This thesis describes in detail the design methodology for the innovative system, estimating the weight savings and establishing the functional benefits for the offshore industry. All-steel Rectangular Honeycomb Core Sandwich Panels (RHCSP) are considered to have a great potential to achieve weight savings while providing adequate structural performance and simple manufacturing and assembly processes. An experimental programme investigating the structural performance of this sandwich topology is presented, aiming at the validation of detailed numerical models. The experimental programme is comprised of small- and large-scale specimens under shear, compressive and flexural loading. A practical assessment and optimisation method for the design of sandwich panel deck systems is developed, supported by detailed finite element analysis which is validated against experimental results. The first step involves establishing the accuracy and computational efficiency of several methods of analysis for sandwich panels, which include detailed and simplified numerical models as well as thin- and thick-plate bending theory. The application of classic plate bending theories allows for an efficient design method to be developed, although with a restricted field of application. When combined with adequate limit state criteria, an accurate prediction of the onset of nonlinear behaviour caused either by material yielding or plate buckling can be achieved. Finally, gradient-based optimisation algorithms are used to achieve optimal designs for sandwich panel deck panels under out-of-plane loading, while genetic algorithms are used to optimise the deck system layout, simultaneously considering the weight of the sandwich panels and the supporting beams, ensuring lightweight and functional solutions.
Sp converted waves reveal the structure of the lithosphere below the Alps and their northern foreland
Creators: name: Kind, Rainer
name: Schmid, Stefan M.
name: Schneider, Felix
name: Meier, Thomas
name: Yuan, Xiaohui
name: Heit, Ben
name: Schiffer, Christian
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: S-to-P converted seismic waves
subject: 500 Natural sciences and mathematics::550 Earth sciences::550 Earth sciences

description: The structure of the lithosphere is reflecting its evolution. The Moho of the European lithosphere has already been studied intensively. This is, however, not yet the case for the lower boundary of the lithosphere, i.e., the lithosphere-asthenosphere boundary (LAB). We are using S-to-P converted seismic waves to study the structures of the Moho and the LAB beneath Europe including the greater Alpine Area with data from the AlpArray project and the European networks of permanent seismic stations. We use plain waveform stacking of converted waves without deconvolution and compare the results with stacking of deconvolved traces. We also compare Moho depths determinations using S-to-P converted waves with those obtained by other seismic methods. We present more detailed information about negative velocity gradients (NVG) below the Moho. Its lower bound may be interpreted as representing the LAB. We found that the thickness of the European mantle lithosphere is increasing from about 50°N towards the Alps along the entire east-west extension of the Alps. The NVG has also an east dipping component towards the Pannonian Basin and the Bohemian Massif. The Alps and their northern foreland north of about 50°N are surrounded in the east, west and north by a north dipping mantle lithosphere. Along 50°N, where the NVG is reversing its dip direction towards the north, is also the area along which the volcanoes of the European Cenozoic Rift System are located. Our results possibly indicate that the Alpine collision has deformed the entire lithosphere of the Alpine foreland as far north as about 50°N.
Label-free electronic detection of biomarkers using nanowell impedance sensor
Creators: name: Xie, Pengfei
Publisher: name: No Publisher Supplied
Year: 2020

description: The application of lab-on-a-chip or microfluidic technologies to perform protein assays is an emerging field and has the potential to be used for point-of-care devices. High-sensitivity and general-use biosensors play a crucial role in achieving this goal. The quantification of protein provides a crucial perspective of pathology, drug treatment, and understanding of the disease. Label-free electronic affinity-based immunosensing is an attractive candidate as a platform technology for analyzing biomarkers due to the ease of miniaturization and the minimal use of reagents. Electronic-based sensing approaches, however, have lagged behind their optical counterparts in terms of detection limit, selectivity, and reliability. In addition, the matrix-dependent nature of electronic sensing modalities makes the analysis of biomarkers in high salt concentration samples, such as the serum, difficult due to charge screening.In this dissertation, I present a novel impedance-based nanowell biosensor and its application in multiple novel solutions for detecting protein biomarkers in purified buffers and serum matrixes using a micro-sized biochip. I discuss sensor fabrication, sample preparation, theoretical considerations, data analysis, and various experiments.In the first chapter, I introduce the fundamental perspective of protein studies and protein quantification and summarize and review the gold standard and state-of-the-art techniques of protein quantification. Next, I introduce the impedance-based biosensors used in protein detection. In the second chapter, I introduce the theory and modeling of the proposed nanowell sensor, including the systematic analysis, determination of the parameters, results of the simulations, and the derivation of the formula. In the third chapter, I propose the nanowell-based label-free assay for the quantitative assessment of cytokine levels, present the results of a series of experiments, and discuss the validity and novelty of the technique. In the fourth chapter, I present multiplexed protein assay measurements achieved using an embedded microprocessor. The standard titration curves of multiple proteins are also presented, followed by the correlation analysis between the nanowell sensor and the Luminex technique and the results of the nanowell sensor to the characteristic biological parameters. In the fifth chapter, I present the most recent results on the analysis of mouse clinical samples with inflammatory arthritis. The results of different experiments with different treatments, a comparison between the standard titration curves of different techniques, and the correlation curves of all samples are presented in this chapter. And in the sixth chapter, the results of human clinical samples including the titration curve of different biomarkers, cytokine levels of different patient samples were introduced.
La postergazione legale dei crediti: l'incentivazione delle condotte finanziarie virtuose di fronte alla crisi
Creators: name: Galletti, Danilo
Publisher: name: Universit� degli Studi di Trento
Year: 2021

description: L?opera ha per oggetto la disciplina della postergazione del finanziamento dei soci alla societ� ed anche nell'ambito dei gruppi, in particolare nel contesto del codice civile, del Codice della Crisi, ed infine della legislazione speciale di contrasto all?evento pandemico. In essa si esamina dapprima il tema della natura giuridica del finanziamento del socio, prendendo in esame tanto le tesi che ne assumono la rilevanza ai fini della graduazione quanto quelle, invero prevalenti in giurisprudenza, che assumono invece la temporanea inesigibilit� dell?obbligazione; e poi quello della ratio della disciplina. Da tale ultima premessa vengono dedotte le conseguenze in ordine alle tipologie di societ� ed alla situazione patrimoniale e finanziaria cui l?istituto deve trovare applicazione, nonch� alla nozione di ?finanziamento?. Viene poi presa in considerazione l?applicazione della speciale disciplina nel contesto regolatorio della crisi, e cos� nell?ambito del concorso, fallimentare o concordatario, con riferimento anche alla possibile convivenza di postergazione e cause di prelazione. Infine vengono analizzate alcune fattispecie concrete tipicamente assai critiche, che pongono in tensione l?applicazione dell?istituto.
The Job Dispatcher sequence analysis tools services from EMBL-EBI in 2022
Creators: name: Madeira, Fabio
name: Lee, Joon
name: Tivey, Adrian
name: Nandana Madhusoodanan
name: Lopez, Rodrigo
name: Butcher, Sarah
Publisher: name: F1000 Research Limited
Year: 2022

description: The Job Dispatcher (JD) tools framework provides free access to popular bioinformatics sequence analysis applications and sequence libraries. The services can be accessed via user-friendly web interfaces and via established RESTful and SOAP Web Services Application Programming Interfaces (APIs), allowing them to be integrated into third-party systems. The services reported here are integrated into many popular data resources provided at the EMBL-EBI, including for example UniProtKB, ENA, Ensembl Genomes and InterPro. Tools running under JD comprise popular bioinformatics applications (e.g. Clustal Omega, InterProScan, FASTA, NCBI BLAST+, and many more), which combined with nucleotide and protein sequence databases (e.g. UniProtKB and ENA) represent powerful tools for SARS-CoV-2 and COVID-19 research. Countless jobs have been performed on EMBL-EBI’s high-performance computing clusters, with a noticeable surge of more than 60 million jobs per month performed during the COVID-19 outbreak months of April and May 2020. Nearly 500 million analyses were executed during 2021 by over 700,000 unique users.
Effect of the Small Watershed Program on Major Uses of Land: Examination of 60 Projects in the Southeast, Mississippi Delta, and Missouri River Tributaries Regions
Creators: name: Mattson, C. Dudley
name: Mattson, C. Dudley
Publisher: name: Unknown
Year: 1975
Subjects: subject: Agricultural and Food Policy
subject: Crop Production/Industries
subject: Environmental Economics and Policy
subject: Land Economics/Use
subject: Small watershed projects
subject: land use
subject: development
subject: flood protection
subject: drainage
subject: Irrigation
subject: projections
subject: benefits

description: Land use changes in 1955-70 on sample areas with installed P.L. 566 Small watershed Improvement projects are compared with sample areas having planned but undeveloped projects, using aerial photographs. Cropland retirement on upland portions of watersheds was more rapid on completed projects than on new ones In the Southeast and Mississippi Delta regions. In the Mississippi region, cropland expansion on protected bottomlands of installed projects was well ahead of the rate of planned projects. In the Southeast, cropland expansion failed to take place. Cropland retirement, typical for the region, also failed to take place. In the Missouri River tributaries region, there was no significant change in the predominant cropland use of both upland and bottomland areas after project installation. Widespread increases in soil-conserving practices were noted on all projects studied in the Missouri River tributaries region. Planners anticipating land use changes from project development should consider additional factors that could modify the expectations of benefited landowners, such as (1) likely available capital and labor for land conversions, (2) size and organization of farm enterprises, and (3) long-term demands for crops suited to climate, soils, and configurations of benefited areas.
Anisotropy and XKS-splitting from geodynamic models of double subduction: Testing the limits of interpretation
Creators: name: Kruse, J. P.
name: Rümpker, G.
name: Link, F.
name: Duretz, T.
name: Schmeling, H.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Geodynamic modelling
subject: XKS-Splitting
subject: Seismic anisotropy
subject: 500 Natural sciences and mathematics::550 Earth sciences::550 Earth sciences

description: In this study, we develop three-dimensional geodynamic models to predict XKS-splitting for double subduction scenarios characterized by two outward dipping slabs. These models are highly relevant in various realistic settings, such as the central Mediterranean. We focus on the analysis of XKS-splitting, a key geophysical observable used to infer seismic anisotropy and mantle flow patterns predicted from these geodynamic models. Our geodynamic models simulate the concurrent subduction of two identical oceanic plates which are separated by a continental plate. The variation of the separating plate strength, cause a transition from a retreating to a stationary trench. The models provide detailed insights into the temporal evolution of mantle flow patterns, especially the amount of trench parallel flow, induced by these double subduction scenarios. In a second step, we use the well-known D-Rex model (Kaminski et al., 2004) to efficiently estimate the CPO development in response to plastic deformation produced by mantle flow. Based on the results of the D-Rex model, which includes the full elastic tensor of a deformed multiphase polycrystalline mantle aggregate within the three-dimensional model, we obtain synthetic apparent splitting parameters at receivers placed at the surface by applying multiple-layer anisotropic waveform modeling. Employing analytical techniques, we show the ambiguous nature of apparent splitting parameters, as already suggested by previous studies based on numerical modeling. In the light of the results, we postulate that a meaningful inversion, based on the commonly applied 2-layer anisotropic model, requires additional constraints on fast-axis orientation or strength of anisotropy (delay time). Finally, we show that constraints from our texture simulations (i.e., the integrated delay time) can be used to achieve unique 2-layer models that perfectly fit the synthetic observables. Such models could serve as reference for the interpretation of the observations. Our study highlights the necessity of combining geodynamic modeling and XKS-splitting analysis to shed light on complex upper mantle flow patterns such as those that might occur around subduction zones.
Generalized nonlocal optical response in nanoplasmonics
Creators: name: Mortensen, N. Asger
name: Raza, Søren
name: Wubs, Martijn
name: Søndergaard, Thomas
name: Bozhevolnyi, Sergey I.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Metallic nanostructures exhibit a multitude of optical resonances associated with localized surface plasmon excitations. Recent observations of plasmonic phenomena at the sub-nanometer to atomic scale have stimulated the development of various sophisticated theoretical approaches for their description. Here instead we present a comparatively simple semiclassical generalized nonlocal optical response (GNOR) theory that unifies quantum-pressure convection effects and induced-charge diffusion kinetics, with a concomitant complex-valued GNOR parameter. Our theory explains surprisingly well both the frequency shifts and size-dependent damping in individual metallic nanoparticles (MNPs) as well as the observed broadening of the cross-over regime from bonding-dipole plasmons to charge-transfer plasmons in MNP dimers, thus unraveling a classical broadening mechanism that even dominates the widely anticipated short-circuiting by quantum tunneling. We anticipate that the GNOR theory can be successfully applied in plasmonics to a wide class of conducting media, including doped semiconductors and low-dimensional materials such as graphene.
description: 7 pages, including 3 figures. Supplementary information is available upon request to authors
Uremic Toxin-Induced Exosome-like Extracellular Vesicles Contain Enhanced Levels of Sulfated Glycosaminoglycans which Facilitate the Interaction with Very Small Superparamagnetic Iron Oxide Particles
Creators: name: Freise, Christian
name: Zappe, Andreas
name: Löwa, Norbert
name: Schnorr, Jörg
name: Pagel, Kevin
name: Wiekhorst, Frank
name: Taupitz, Matthias
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: extracellular vesicles
subject: uremic toxins
subject: VSOP
subject: glycosaminoglycans
subject: exosomes
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::547 Organische Chemie

description: Uremic toxins exert pathophysiological effects on cells and tissues, such as the generation of a pro-calcifying subtype of exosome-like extracellular vesicles (EVs) in vascular cells. Little is known about the effects of the toxins on the surface structure of EVs. Thus, we studied the effects of uremic toxins on the abundance of sulfated glycosaminoglycans (GAGs) in EVs, and the implications for binding of ligands such as very small superparamagnetic iron oxide particles (VSOPs) which could be of relevance for radiological EV-imaging. Vascular cells were treated with the uremic toxins NaH2PO4 and a mixture of urea and indoxyl sulfate. Uremia in rats was induced by adenine feeding. EVs were isolated from culture supernatants and plasma of rats. By proton T1-relaxometry, magnetic particle spectroscopy, and analysis of genes, proteins, and GAG-contents, we analyzed the roles of GAGs in the ligand binding of EVs. By influencing GAG-associated genes in host cells, uremic toxins induced higher GAG contents in EVs, particularly of sulfated chondroitin sulfate and heparan sulfate chains. EVs with high GAG content interacted stronger with VSOPs compared to control ones. This was confirmed by experiments with GAG-depleted EVs from genetically modified CHO cells and with uremic rat-derived EVs. Mechanistically, uremic toxin-induced PI3K/AKT-signaling and expression of the sulfate transporter SLC26A2 in host cells contributed to high GAG contents in EVs. In conclusion, uremic conditions induce enhanced GAG contents in EVs, which entails a stronger interaction with VSOPs. VSOPs might be suitable for radiological imaging of EVs rich in GAGs.
Neue Ansätze zur Charakterisierung von dezellularisierten Geweben und zur Rebesiedelung von Gefäßen
Creators: name: Hillebrandt, Karl Herbert
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: decellularization
subject: recellularization
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Die Organ bzw. Gewebe De- und Rezellularisierung stellt ein spannendes Teilgebiet des Tissue Engineering dar. Diese Habilitationsschrift setzt sich mit der tiefgreifenden Charakterisierung von dezellularisierten Geweben auseinander. Ein weiterer wichtiger Aspekt, welcher in dieser Arbeit behandelt wird ist die Reendothelialisierung von Gefäßen.
Scattering of flexural acoustic phonons at grain boundaries in graphene
Creators: name: Helgee, Edit E.
name: Isacsson, Andreas
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the scattering of long-wavelength flexural phonons against grain boundaries in graphene using molecular dynamics simulations. Three symmetric tilt grain boundaires are considered: one with a misorientation angle of $17.9^\circ$ displaying an out-of-plane buckling 1.5 nm high and 5 nm wide, one with a misorientation angle of $9.4^\circ$ and an out-of-plane buckling 0.6 nm high and 1.7 nm wide, and one with a misorientation angle of $32.2^\circ$ and no out-of-plane buckling. At the flat grain boundary, the phonon transmission exceeds 95 % for wavelengths above 1 nm. The buckled boundaries have a substantially lower transmission in this wavelength range, with a minimum transmission of 20 % for the $17.9^\circ$ boundary and 40 % for the $9.4^\circ$ boundary. At the buckled boundaries, coupling between flexural and longitudinal phonon modes is also observed. The results indicate that scattering of long-wavelength flexural phonons at grain boundaries in graphene is mainly due to out-of-plane buckling. A continuum mechanical model of the scattering process has been developed, providing a deeper understanding of the scattering process as well as a way to calculate the effect of a grain boundary on long-wavelength flexural phonons based on the buckling size.
description: 11 pages, 14 figures