cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Evaluation & Impact of Anti Tuberculosis Drug Lines against an MDR - Mycobacterium tuberculosis isolates
Creators: name: HK Garg
Publisher: name: figshare
Year: 2018
Subjects: Biotechnology

description: The present communiqué renders a comparative account of evaluation and impact of anti-tuberculosis drugs against an Multiple-drug-resistant strain of tuberculosis (MDR-TB). MDR-TB is known to be resistant to isoniazid and rifampicin, in vitro. It defies the effectiveness of standard treatments and, in turn, contributes to increased mortality. It is widespread in some countries, especially the former USSR, where, the rates of MDR-TB among ‘newly enrolled’ and ‘non-responding’ prisoners were 24.6% and 92.1%, respectively. In the Russian Federation, high rates of MDR-TB (23 – 50%) have been registered among sputum smear-positive individuals receiving fully administered short-term treatments with first-line drugs. In the USA, 3.5% of tuberculosis strains were found resistant to isoniazid and rifampicin at the time of the outbreak of tuberculosis in early 1990s.Six classes of second-line drugs - aminoglycosides, fluoroquinolones, poly peptides, thioamides, cycloserine and p-aminosalicylic acid have been catalogued for the treatment of TB. Recently, an extensively drug-resistant (XDR) strain of M. tuberculosis has been observed which shows no response to isoniazid, rifampin, fluoroquinolone and aminoglycoside. XDR-TB is the most severe form of tuberculosis, against which no effective drug has been identified till date. However, a new generation TBK-613 of fluoroquinolone is on trial to treat this severe form of tuberculosis.Medicinal plants offer a great hope to fulfill this void. Plants are being used as pure compounds as well as crude bits & pieces to cure tuberculosis since medieval times. However, our scientific understanding and registrations are still not up to date. The present study makes valid comparison among different anti-tuberculosis drug against Mycobacterium tuberculosis isolates and hit upon the susceptibility of Mycobacterium tuberculosis against different medicinal plants.
Matrix 3-Lie superalgebras and BRST supersymmetry
Creators: name: Abramov, Viktor
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Rings and Algebras (math.RA)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 15A66, 17A70, 17B66, 17B60, 17B81

description: Given a matrix Lie algebra one can construct the 3-Lie algebra by means of the trace of a matrix. In the present paper we show that this approach can be extended to the infinite-dimensional Lie algebra of vector fields on a manifold if instead of the trace of a matrix we consider a differential 1-form which satisfies certain conditions. Then we show that the same approach can be extended to matrix Lie superalgebras if instead of the trace of a matrix we make use of the super trace of a matrix. It is proved that a graded triple commutator of matrices constructed with the help of the graded commutator and the super trace satisfies a graded ternary Filippov-Jacobi identity. In two particular cases and we show that the Pauli and Dirac matrices generate the matrix 3-Lie superalgebras, and we find the non-trivial graded triple commutators of these algebras. We propose a Clifford algebra approach to 3-Lie superalgebras induced by Lie superalgebras. We also discuss an application of matrix 3-Lie superalgebras in BRST-formalism.
description: 18 pages, manuscript is accepted for publication in International Journal of Geometric Methods in Modern Physics
Optical Coherence Tomography (OCT)
Creators: name: Iwanicka, Magdalena
name: Sylwestrzak, Marcin
name: Szkulmowska, Anna
name: Targowski, Piotr
Publisher: name: Zenodo
Year: 2019
Subjects: noninvasive examination
varnish

description: The fundamentals of the OCT technique are given and the details of its application to the research presented in this book.
Heat and Worker Health
Creators: name: Ireland, Andrew
name: Johnston, David
name: Knott, Rachel
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Economics (econ.GN)
subject: FOS: Economics and business

description: Extreme heat negatively impacts cognition, learning, and task performance. With increasing global temperatures, workers may therefore be at increased risk of work-related injuries and illness. This study estimates the effects of temperature on worker health using records spanning 1985-2020 from an Australian mandatory insurance scheme. High temperatures are found to cause significantly more claims, particularly among manual workers in outdoor-based industries. These adverse effects have not diminished across time, with the largest effect observed for the 2015-2020 period, indicating increasing vulnerability to heat. Within occupations, the workers most adversely affected by heat are female, older-aged and higher-earning. Finally, results from firm-level panel analyses show that the percentage increase in claims on hot days is largest at "safer" firms.
Development of deformation-tunable quadrupolar microcavity
Creators: name: Yang, Juhee
name: Moon, Songky
name: Lee, Sang-Bum
name: Kim, Sang-Wook
name: Shim, Jeong-Bo
name: Lee, Hai-Woong
name: Lee, Jai-Hyung
name: An, Kyungwon
Publisher: name: arXiv
Year: 2006
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We have developed a technique for realizing a two-dimensional quadrupolar microcavity with its deformation variable from 0% to 20% continuously. We employed a microjet ejected from a noncircular orifice in order to generate a stationary column with modulated quadrupolar deformation in its cross section. Wavelength red shifts of low-order cavity modes due to shape deformation were measured and were found to be in good agreement with the wave calculation for the same deformation, indicating the observed deformation is quadrupolar in nature.
description: 7 pages, 6 figures, intended for Rev. Sci. Instum
Trainstation: A unified virtual environment for programming training
Creators: name: Wilson, Aidan
Publisher: name: Zenodo
Year: 2023

description: Introduction
Intersect has been at the forefront of delivering large-scale programming training since 2015, with Python and R emerging as our most popular courses. As our training program expanded in terms of both courseware and popularity, the need for robust infrastructure has become paramount.

Methods
To address these challenges, Intersect this year launched Trainstation; a unified training environment for delivering programming training. Trainstation leverages the Nectar research cloud, providing complete control over the configuration of packages and data, and simplifying access for attendees. Building on a reliable stack of existing technologies, Trainstation minimises administrative burden and automates mundane tasks in planning and delivering training, such as the management of user accounts, training data, and software.

Results
The implementation of Trainstation has further enhanced the trainee experience, as attendees no longer need to worry about installations and package downloads. Trainers can immediately focus on the teaching, and are also empowered to troubleshoot issues more simply, as trainees' code exists in a single environment that trainers can inspect. Trainstation also simplifies administration; allowing libraries, packages and data to be updated once and applying to all trainees. Finally, leveraging the Nectar cloud enables scalability, allowing expansion of resources for larger courses or workshops with higher computational requirements.

Conclusion
By simplifying access and eliminating technical barriers, Trainstation empowers instructors to focus on teaching while providing attendees with a fully configured coding environment. This presentation will demonstrate Trainstation, focusing on how it enhances the overall training experience for trainees, trainers, and training administrators.
Consternations over Genetically Designed Products : A Recap
Creators: name: HK Garg
name: Garg, Jaya
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: There has been a widespread concern in public regarding the hazards of Genetically Designed Food. The introduction of wonder products such as DDT & PCBs and their subsequent withdrawal after encounter with unforeseen problems has undermined public trust in companies that introduce products and in those government agencies which regulate them. There is also a widespread sense that social and technological change is speeding up and people feel powerless to affect this change. Apprehensions on an issue get magnified when the product is food that is being changed.Though there is a broad scientific consensus that GE crops on the market are safe enough to eat, yet some scientists and advocacy groups such as Greenpeace and World Wildlife Fund have concerns that GM food may not be safe enough and that contemporary testing regimes are not adequate to ensure sufficient safety. The current communiqué put forth a construal of scientific confab on this international concern.
Analysis of Electron Correlation Effects in Strongly Correlated Systems ($\rm N_2$ and $\rm N_2^+$) by applying DMRG and Quantum Information Theory
Creators: name: Stemmle, Christian
name: Legeza, Örs
name: Paulus, Beate
Publisher: name: arXiv
Year: 2017
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The dissociation of $\rm N_2$ and $\rm N_2^+$ has been studied by using the \emph{ab initio} Density Matrix Renormalization Group (DMRG) method. Accurate Potential Energy Surfaces (PES) have been obtained for the electronic ground states of $\rm N_2$ ($\rm X^1Σ_g^+$) and $\rm N_2^+$ ($\rm X^2Σ_g^+$) as well as for the $\rm N_2^+$ excited state $\rm B^2Σ_u^+$. Inherently to the DMRG approach, the eigenvalues of the reduced density matrix ($ρ$) and their correlation functions are at hand. Thus we can apply Quantum Information Theory (QIT) directly, and investigate how the wave function changes along the PES and depict differences between the different states. Moreover by characterizing quantum entanglement between different pairs of orbitals and analyzing the reduced density matrix, we achieved a better understanding of the multi-reference character featured by these systems.
description: 35 pages, 13 figures
Long-term Spectral Variability of the Ultra-luminous X-ray source Holmberg IX X--1
Creators: name: Jithesh, V.
name: Misra, Ranjeev
name: Wang, Zhongxiang
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We investigate the long-term spectral variability in the ultra-luminous X-ray source Holmberg IX X--1. By analyzing the data from eight {\it Suzaku} and 13 {\it XMM-Newton} observations conducted between 2001 and 2015, we perform a detailed spectral modeling for all spectra with simple models and complex physical models. We find that the spectra can be well explained by a disc plus thermal Comptonization model. Applying this model, we unveil correlations between the X-ray luminosity ($L_{\rm X}$) and the spectral parameters. Among the correlations, a particular one is the statistically significant positive correlation between $L_{\rm X}$ and the photon index ($Γ$), while at the high luminosities of $> 2\times10^{40}\,{\rm~erg\ s}^{-1}$, the source becomes marginally hard and that results a change in the slope of the $Γ- L_{\rm X}$ correlation. Similar variability behavior is observed in the optical depth of the source around $L_{\rm X} \sim 2\times10^{40}\,{\rm~erg\ s}^{-1}$ as the source becomes more optically thick. We consider the scenario that a corona covers the inner part of the disc, and the correlations can be explained as to be driven by the variability of seed photons from the disc input into the corona. On the basis of the disc-corona model, we discuss the physical processes that are possibly indicated by the variability of the spectral parameters. Our analysis reveals the complex variability behavior of Holmberg IX X--1 and the variability mechanism is likely related to the geometry of the X-ray emitting regions.
description: Accepted for publication in ApJ, 12 Pages, 3 Tables, 3 Figures
Ferromagnetic fluid as a model of social impact
Creators: name: Fronczak, Piotr
name: Fronczak, Agata
name: Hołyst, Janusz A.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: The paper proposes a new model of spin dynamics which can be treated as a model of sociological coupling between individuals. Our approach takes into account two different human features: gregariousness and individuality. We will show how they affect a psychological distance between individuals and how the distance changes the opinion formation in a social group. Apart from its sociological aplications the model displays the variety of other interesting phenomena like self-organizing ferromagnetic state or a second order phase transition and can be studied from different points of view, e.g. as a model of ferromagnetic fluid, complex evolving network or multiplicative random process.
description: 8 pages, 5 figures
Large-N Collective Field Theory Applied to Anyons in Magnetic Fields
Creators: name: Hiro-Oka, H.
name: Minakata, H.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a large-$N$ collective field formalism for anyons in external magnetic fields interacting with arbitrary two-body potential. We discuss how the Landau level is reproduced in our framework. We apply it to the soluble model for anyons proposed by Girvin et al., and obtain the dispersion relation of collective modes for arbitrary statistical parameters.
description: 10 pages(Plain TeX) TMUP-HEL-9306
Thermally-induced spin polarization in a magnetized two-dimensional electron gas with Rashba spin-orbit interaction
Creators: name: Dyrdal, A.
name: Barnas, J.
name: Dugaev, V. K.
name: Berakdar, J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Spin polarization induced by a temperature gradient (heat-current) in a magnetized two-dimensional electron gas (2DEG) with Rashba spin-orbit interaction is considered theoretically within the linear response theory. Using the Matsubara Green function formalism we calculate the temperature dependence of the spin polarization for arbitrary orientation of the exchange field. The limit of a nonmagnetic 2DEG (zero exchange field) is also considered. The physical mechanisms of the spin polarization within our scheme are discussed.
description: 9 pages, 3 figures
CoderEval: A Benchmark of Pragmatic Code Generation with Generative Pre-trained Models
Creators: name: Yu, Hao
name: Shen, Bo
name: Ran, Dezhi
name: Zhang, Jiaxin
name: Zhang, Qi
name: Ma, Yuchi
name: Liang, Guangtai
name: Li, Ying
name: Wang, Qianxiang
name: Xie, Tao
Publisher: name: arXiv
Year: 2023
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Code generation models based on the pre-training and fine-tuning paradigm have been increasingly attempted by both academia and industry, resulting in well-known industrial models such as Codex, CodeGen, and PanGu-Coder. To evaluate the effectiveness of these models, multiple existing benchmarks are proposed, including only cases of generating a standalone function, i.e., a function that may invoke or access only built-in functions and standard libraries. However, non-standalone functions, which typically are not included in the existing benchmarks, constitute more than 70% of the functions in popular open-source projects, and evaluating models' effectiveness on standalone functions cannot reflect these models' effectiveness on pragmatic code generation scenarios.
 To help bridge the preceding gap, in this paper, we propose a benchmark named CoderEval, consisting of 230 Python and 230 Java code generation tasks carefully curated from popular real-world open-source projects and a self-contained execution platform to automatically assess the functional correctness of generated code. CoderEval supports code generation tasks from six levels of context dependency, where context refers to code elements such as types, APIs, variables, and consts defined outside the function under generation but within the dependent third-party libraries, current class, file, or project. CoderEval can be used to evaluate the effectiveness of models in generating code beyond only standalone functions. By evaluating three code generation models on CoderEval, we find that the effectiveness of these models in generating standalone functions is substantially higher than that in generating non-standalone functions. Our analysis highlights the current progress and pinpoints future directions to further improve a model's effectiveness by leveraging contextual information for pragmatic code generation.
Manifest Modular Invariance in the Near-Critical Ising Model
Creators: name: Berg, Marcus
Publisher: name: arXiv
Year: 2023
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Using recent results in mathematics, I point out that free energies and scale-dependent central charges away from criticality can be represented in compact form where modular invariance is manifest. The main example is the near-critical Ising model on a thermal torus, but the methods are not restricted to modular symmetry, and apply to automorphic symmetries more generally. One application is finite-size effects.
description: 23 pages, 7 figures
Allicin as a potent antibiotic against dermal infections
Creators: name: Shrivastava, Ashish
name: HK Garg
Publisher: name: figshare
Year: 2018
Subjects: Biotechnology

description: Allicin is commonly known for its anti-diarrheal, anti-fungal, anti-choleretic and anti-cancerous activity in traditional system of Indian medicine. In the present study, Allicin was administered in vitro for antibacterial activity against four Gram positive strains - Staphylococcus saprophyticus, Staphylococcus epidermis, Staphylococcus aureus & Streptococcus pyogenes and four Gram negative strains - Proteus mirabilis, Proteus vulgaris, Klebsiella pneumonia & Neisseria meningitis.These bacterial strains cause skin disease in humans. The extracts showed significant antibacterial activities against both the (Gram-positive and Gram-negative) bacterial strains at 100, 200, and 300 µg/disc concentrations using Disc Diffusion Method. tested. Highest antibacterial activity was evident against Staphylococcus saprophyticus (at 300 µg/disc : 24.00 ± 0.00 mm) and the least activity was noticed against Klebsiella pneumoniae (at 300 µg/disc : 6.00 ± 0.00mm). The minimum inhibitory concentration (MIC) ranged between 100 µg /mL and 200 µg /mL depending on microorganism.The results suggest allicin as an antibacterial substance for the treatment of skin infections caused by pathogenic bacterial strains.
Cosmic Rays above $10^{14}$ eV
Creators: name: Boratav, Murat
name: Watson, Alan A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We briefly review the status of cosmic ray studies between $10^{14}$ eV and the highest observed energies, namely a few times $10^{20}$ eV. Because of the rather low incident fluxes in this energy range, the studies mostly rely on ground based, large aperture detectors reconstructing the cosmic ray's properties through the detection of the air-showers they generate by interacting with the atmosphere. We stress the fact that many issues such as the chemical composition of the cosmic rays, their acceleration mechanisms, the structures displayed in their energy spectrum are mostly open questions which may be answered by the next generation of experiments.
description: 11 pages, 5 figures, Latex2e, one reference modified
Enhancing synchronization in chaotic oscillators by induced heterogeneity
Creators: name: Banerjee, Ranjib
name: Bera, Bidesh K.
name: Ghosh, Dibakar
name: Dana, Syamal Kumar
Publisher: name: arXiv
Year: 2017
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: We report enhancing of complete synchronization in identical chaotic oscillators when their interaction is mediated by a mismatched oscillator. The identical oscillators now interact indirectly through the intermediate relay oscillator. The induced heterogeneity in the intermediate oscillator plays a constructive role in reducing the critical coupling for a transition to complete synchronization. A common lag synchronization emerges between the mismatched relay oscillator and its neighboring identical oscillators that leads to this enhancing effect. We present examples of one-dimensional open array, a ring, a star network and a two-dimensional lattice of dynamical systems to demonstrate how this enhancing effect occurs. The paradigmatic Rössler oscillator is used as a dynamical unit, in our numerical experiment, for different networks to reveal the enhancing phenomenon.
description: 10 pages, 7 figures
Spontaneous pain in non-obese and obese adults: Systematic Review and Meta-analysis.
Creators: name: Álvarez, Miguel
name: García, Miguel
name: Cordón, Patricia
name: García, Carlos
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences

description: The systematic review and meta-analysis will carry out following the Cochrane Handbook for Systematic Review of Intervention and the guide "Preferred Reporting Items for Systematic Reviews, PRISMA”. The following databases will be searched: EMBASE, CINAHL, Cochrane Library, PubMed, SCOPUS, WEB of SCIENCE and PEDro. The search strategy is based on keywords. The keywords used will be obesity, overweight and pain.
DESI z >~ 5 Quasar Survey. I. A First Sample of 400 New Quasars at z ~ 4.7-6.6
Creators: name: Yang, Jinyi
name: Fan, Xiaohui
name: Gupta, Ansh
name: Myers, Adam
name: Palanque-Delabrouille, Nathalie
name: Wang, Feige
name: Yèche, Christophe
name: Aguilar, Jessica Nicole
name: Ahlen, Steven
name: Alexander, David
name: Brooks, David
name: Dawson, Kyle
name: de la Macorra, Axel
name: Dey, Arjun
name: Dhungana, Govinda
name: Fanning, Kevin
name: Font-Ribera, Andreu
name: Gontcho, Satya
name: Guy, Julien
name: Honscheid, Klaus
name: Juneau, Stephanie
name: Kisner, Theodore
name: Kremin, Anthony
name: Guillou, Laurent Le
name: Levi, Michael
name: Magneville, Christophe
name: Martini, Paul
name: Meisner, Aaron
name: Miquel, Ramon
name: Moustakas, John
name: Nie, Jundan
name: Percival, Will
name: Poppett, Claire
name: Prada, Francisco
name: Schlafly, Edward
name: Tarlé, Gregory
name: Magana, Mariana Vargas
name: Weaver, Benjamin Alan
name: Wechsler, Risa
name: Zhou, Rongpu
name: Zhou, Zhimin
name: Zou, Hu
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report the first results of a high-redshift ($z$ >~ 5) quasar survey using the Dark Energy Spectroscopic Instrument (DESI). As a DESI secondary target program, this survey is designed to carry out a systematic search and investigation of quasars at $z$ >~ 5, up to redshift 6.8. The target selection is based on the DESI Legacy Imaging Surveys (the Legacy Surveys) DR9 photometry, combined with the Pan-STARRS1 data and $J$-band photometry from public surveys. A first quasar sample has been constructed from the DESI Survey Validation 3 (SV3) and first-year observations until May 2022. This sample includes more than 400 new quasars at redshift 4.7 <= $z$ < 6.6, down to 21.5 magnitude in the $z$ band, discovered from 35% of the entire target sample. Remarkably, there are 220 new quasars identified at $z$ >= 5, more than one third of existing quasars previously published at this redshift. The observations so far result in an average success rate of 23% at $z$ > 4.7. The current spectral dataset has already allowed analysis of interesting individual objects (e.g., quasars with damped Ly$α$ absorbers and broad absorption line features), and statistical analysis will follow the survey's completion. A set of science projects will be carried out leveraging this program, including quasar luminosity function, quasar clustering, intergalactic medium, quasar spectral properties, intervening absorbers, and properties of early supermassive black holes. Additionally, a sample of 38 new quasars at $z$ ~ 3.8-5.7 discovered from a pilot survey in the DESI SV1 is also published in this paper.
description: 28 pages, 9 figures, and 2 tables; Published in ApJS
Computational probes of molecular motion in the Lewis and Whanstrom model for ortho-terphenyl
Creators: name: Lombardo, Thomas G.
name: Debenedetti, Pablo G.
name: Stillinger, Frank H.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We use molecular dynamics simulations to investigate translational and rotational diffusion in a rigid three-site model of the fragile glass former ortho-terphenyl, at 260 K < T < 346 K and ambient pressure. An Einstein formulation of rotational motion is presented, which supplements the commonly-used Debye model. The latter is shown to break down at supercooled temperatures as the mechanism of molecular reorientation changes from small random steps to large infrequent orientational jumps. We find that the model system exhibits non-Gaussian behavior in translational and rotational motion, which strengthens upon supercooling. Examination of particle mobility reveals spatially heterogeneous dynamics in translation and rotation, with a strong spatial correlation between translationally and rotationally mobile particles. Application of the Einstein formalism to the analysis of translation-rotation decoupling results in a trend opposite to that seen in conventional approaches based on the Debye formalism, namely an enhancement in the effective rate of rotational motion relative to translation upon supercooling.
description: 11 pages, 8 figures, 1 table
Anticancer Drugs : Difficulties in Development & Usage
Creators: name: Shrivastava, Ashish
name: HK Garg
Publisher: name: figshare
Year: 2018
Subjects: Biotechnology

description: Cancer is one among the scariest and deadly diseases in the world, terrifying mankind largely for the reason that it is difficult to live through it. Since, cancer results from the unrestrained proliferation of subtly modified normal human cells, it’s neither easy to track it nor to curb it. One of the contemporary solutions to alleviate malignancy comprise drug therapy (chemotherapy) despite the very well known fact that majority of drugs used for cancer treatment are cytotoxic that work by interfering in some ways with the operation of the cell's DNA.Cytotoxic drugs are extremely harmful to the body unless they are specific to the cancer cells in question - a situation highly implausible to achieve because of subtle modifications that transform a healthy cell into a cancerous one. Thus, it is imperative to have new drugs that are more discriminating for cancer cells and consequently have lesser side-effects. Gone are the days when the specificity of drugs was to be worked out on animals, now it is possible to have specific drug for cancer specific cells through computer assisted drug design technology. Even then, over the last fifty years, more than 500,000 natural and synthetic chemical compounds have been tested for anticancer activity, however, barely 25 of them are commonly used these days. At present, drugs are on hand that significantly downsize the mortality rates in cases of leukaemia, testicular and ovarian cancer, ensuring longevity of life. Still, we have miles to go before truly curative drugs would be available for most cancers since it is not so easy to synthesise a drug that can discriminate between a normal cell and a mutated one.
Optimal Photon Localization
Creators: name: Mourad, J.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that there is only one operator having some minimal properties enabling it to be a one photon position operator. These proerties are stated, and the solution is shown to be the photon position operator proposed by Pryce. This operator has non-commuting components. Nevertheless, it is shown that one can find states localized with an arbitrary precision.
description: 6 pages
A Deep Chandra X-ray Study of Neutron Star Coalescence GW170817
Creators: name: Haggard, Daryl
name: Nynka, Melania
name: Ruan, John J.
name: Kalogera, Vicky
name: Cenko, S. Bradley
name: Evans, Phil
name: Kennea, Jamie A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report Chandra observations of GW170817, the first neutron star-neutron star merger discovered by the joint LIGO-Virgo Collaboration, and the first direct detection of gravitational radiation associated with an electromagnetic counterpart, Fermi short gamma-ray burst GRB 170817A. The event occurred on 2017 August 17 and subsequent observations identified an optical counterpart, SSS17a, coincident with NGC 4993 (~10 arcsec separation). Early Chandra (Δt ~ 2 days) and Swift (Δt ~ 1-3 days) observations yielded non-detections at the optical position, but ~9 days post-trigger Chandra monitoring revealed an X-ray point source coincident with SSS17a. We present two deep Chandra observations totaling ~95 ks, collected on 2017 September 01-02 (Δt ~ 15-16 days). We detect X-ray emission from SSS17a with L_{0.3-10 keV} = 2.6^{+0.5}_{-0.4} x 10^38 ergs, and a power law spectrum of Gamma = 2.4 +/- 0.8. We find that the X-ray light curve from a binary NS coalescence associated with this source is consistent with the afterglow from an off-axis short gamma-ray burst, with a jet angled >~23 deg from the line of sight. This event marks both the first electromagnetic counterpart to a LIGO-Virgo gravitational-wave source and the first identification of an off-axis short GRB. We also confirm extended X-ray emission from NGC 4993 (L_{0.3-10 keV} ~ 9 x 10^38 ergs) consistent with its E/S0 galaxy classification, and report two new Chandra point sources in this field, CXOU J130948 and CXOU J130946.
description: ApJL, published 2017 Oct 16
The Formation of a Bound Star Cluster: From the Orion Nebula Cluster to the Pleiades
Creators: name: Kroupa, P.
name: Aarseth, S. J.
name: Hurley, J.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: (shortened) Direct N-body calculations are presented of the formation of Galactic clusters using GasEx, which is a variant of the code Nbody6. The calculations focus on the possible evolution of the Orion Nebula Cluster (ONC) by assuming that the embedded OB stars explosively drove out 2/3 of its mass in the form of gas about 0.4 Myr ago. A bound cluster forms readily and survives for 150 Myr despite additional mass loss from the large number of massive stars, and the Galactic tidal field. This is the very first time that cluster formation is obtained under such realistic conditions. The cluster contains about 1/3 of the initial 10^4 stars, and resembles the Pleiades Cluster to a remarkable degree, implying that an ONC-like cluster may have been a precursor of the Pleiades. This scenario predicts the present expansion velocity of the ONC, which will be measurable by upcoming astrometric space missions (DIVA and GAIA). These missions should also detect the original Pleiades members as an associated expanding young Galactic-field sub-population. The results arrived at here suggest that Galactic clusters form as the nuclei of expanding OB associations.
description: MNRAS, in press, 36 pages, 15 figures; repl.vers. contains adjustments for consistency with published version
The aviation industry is an essential component of global commerce and transportation, but it is also a prime target for money laundering. The ease of international movement, high-value transactions, and the use of complex ownership structures make it a sector vulnerable to financial crime. This white paper examines how illicit actors exploit aviation to launder money, explores key vulnerabilities, and evaluates current regulatory efforts. It further provides strategic recommendations for industry stakeholders, including financial institutions, regulators, airlines, and law enforcement agencies, to fortify anti-money laundering (AML) measures and ensure transparency within the sector.
Creators: name: Schofield, Leonard
Publisher: name: Zenodo
Year: 2025
Subjects: kyc
compliance
tech
aml
ctr
sar

description: The aviation industry is an essential component of global commerce and transportation, but it is also a prime target for money laundering. The ease of international movement, high-value transactions, and the use of complex ownership structures make it a sector vulnerable to financial crime. This white paper examines how illicit actors exploit aviation to launder money, explores key vulnerabilities, and evaluates current regulatory efforts. It further provides strategic recommendations for industry stakeholders, including financial institutions, regulators, airlines, and law enforcement agencies, to fortify anti-money laundering (AML) measures and ensure transparency within the sector.
Allicin as a Potential Inducer of Apoptosis in Cancer Cells
Creators: name: HK Garg
name: A.Choudhary
Publisher: name: figshare
Year: 2018
Subjects: Biotechnology

description: Allicin is a major biologically active component, present in freshly sliced garlic bulbs (Allium sativum). It has been used by Indians, Greeks, Egyptians and Chinese to treat various diseases such as cardiovascular complications, arthritis, pulmonary congestions, abdominal over-growth, diarrhea and worm infestations.
Charge trapping in polymer transistors probed by terahertz spectroscopy and scanning probe potentiometry
Creators: name: Lloyd-Hughes, J.
name: Richards, T.
name: Sirringhaus, H.
name: Castro-Camus, E.
name: Herz, L. M.
name: Johnston, M. B.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Terahertz time-domain spectroscopy and scanning probe potentiometry were used to investigate charge trapping in polymer field-effect transistors fabricated on a silicon gate. The hole density in the transistor channel was determined from the reduction in the transmitted terahertz radiation under an applied gate voltage. Prolonged device operation creates an exponential decay in the differential terahertz transmission, compatible with an increase in the density of trapped holes in the polymer channel. Taken in combination with scanning probe potentionmetry measurements, these results indicate that device degradation is largely a consequence of hole trapping, rather than of changes to the mobility of free holes in the polymer.
description: 4 pages, 3 figures
Highly Charged Ions in a Dilute Plasma: An Exact Asymptotic Solution Involving Strong Coupling
Creators: name: Brown, Lowell S.
name: Dooling, David C.
name: Preston, Dean L.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Astrophysics (astro-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The ion sphere model introduced long ago by Salpeter is placed in a rigorous theoretical setting. The leading corrections to this model for very highly charged but dilute ions in thermal equilibrium with a weakly coupled, one-component background plasma are explicitly computed, and the subleading corrections shown to be negligibly small. This is done using effective field theory methods advocated by Brown and Yaffe. Thus, corrections to nuclear reaction rates that such highly charged ions may undergo can be computed precisely. Moreover, their contribution to the equation of state can also be computed with precision. Such analytic results for very strong coupling are rarely available, and they can serve as benchmarks for testing computer models in this limit.
description: 23 pages, 2 figures. To be published in Physical Review E. Expanded discussion of the equation of state included for clarity
title: Inventaire de la Babeau, de Valençay - Archives départementales de l'Indre, 5 B 874 P 31
Creators: name: de l'Indre, archives départementales
name: Archives Départementales De L'Indre
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: LaMOP
subject: Laboratoire de médiévistique occidentale de Paris

description: Dans le registre de la justice de Valençay, le greffier-notaire Jean Diver a noté dans le désordre plusieurs actes concernant ses clients, notamment le testament et l’inventaire après décès d’une femme de Valençay (acte publié dans la Revue de l’Académie du Centre, 1997, p. 135-136).
Archives départementales de l’Indre, 5 B 874 p. 31
Document transcrit par M. du Pouget, Archiviste, paléographe, Directeur des Archives départementales de l'Indre
description: Source: https://www.indre.fr/cours-de-pal%C3%A9ographie-n%C2%B0-39
description: Source: https://www.nakala.fr/10.34847/nkl.ca20li2i
description: Inventaire de la Babeau, de Valençay - Archives départementales de l'Indre, 5 B 874 P 31
Finite-size and finite bond dimension effects of tensor network renormalization
Creators: name: Ueda, Atsushi
name: Oshikawa, Masaki
Publisher: name: arXiv
Year: 2023
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We propose a general procedure for extracting the running coupling constants of the underlying field theory of a given classical statistical model on a two-dimensional lattice, combining tensor network renormalization (TNR) and the finite-size scaling theory of conformal field theory. By tracking the coupling constants at each scale, we are able to visualize the renormalization group (RG) flow and demonstrate it with the classical Ising and 3-state Potts models. Furthermore, utilizing the new methodology, we reveal the limitations due to finite bond dimension D on TNR applied to critical systems. We find that a finite correlation length is imposed by the finite bond dimension in TNR, and it can be attributed to an emergent relevant perturbation that respects the symmetries of the system. The correlation length shows the same power-law dependence on D as the "finite entanglement scaling" of the Matrix Product States.
Dominance of hole-boring radiation pressure acceleration regime with thin ribbon of ionized solid hydrogen
Creators: name: Psikal, J.
name: Matys, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Laser-driven proton acceleration from novel cryogenic hydrogen target of the thickness of tens of microns irradiated by multiPW laser pulse is investigated here for relevant laser parameters accessible in near future. It is demonstrated that the efficiency of proton acceleration from relatively thick hydrogen solid ribbon largely exceeds the acceleration efficiency for a thinner ionized plastic foil, which can be explained by enhanced hole boring driven by laser ponderomotive force in the case of light ions and lower target density. Three-dimensional (3D) particle-in-cell (PIC) simulations of laser pulse interaction with relatively thick hydrogen target show larger energies of protons accelerated in the target interior during the hole boring phase and reduced energies of protons accelerated from the rear side of the target by quasistatic electric field compared with the results obtained from two-dimensional (2D) PIC calculations. Linearly and circularly polarized multiPW laser pulses of duration exceeding 100 fs show similar performance in terms of proton acceleration from both the target interior as well as from the rear side of the target. When ultrashort pulse ($\sim$ 30 fs) is assumed, the number of accelerated protons from the target interior is substantially reduced.
REDCap Platform-as-a-Service
Creators: name: Wilson, Aidan
Publisher: name: Zenodo
Year: 2023

description: Background
In early 2023, critical vulnerabilities were exposed in REDCap, posing a significant risk to the data stored by over 6000 partners worldwide. This incident highlighted a widespread issue: the lack of IT support for REDCap among smaller universities, medical research institutes, and non-profit organisations. REDCap's licence constraints, coupled with the absence of a vendor support model, further contribute to the reluctance of IT departments to provide support for REDCap.

Actions
Recognising the challenges faced by these institutions, Intersect leveraged its decade of experience with REDCap and developed the REDCap Platform-as-a-Service (PaaS) offering: a hosted environment with the virtual infrastructure necessary to run REDCap effectively while complying with REDCap's licence terms, providing a viable alternative for institutions lacking IT support.

Results
The REDCap PaaS offering provides smaller institutions with a comprehensive environment consisting of development and production application servers, along with the flexibility of a local or external database, and optional AAF Authentication. The PaaS platform also comes with support from Intersect's team of engineers and analysts who understand REDCap, both technically and administratively.

Conclusion
By adhering to licence terms and providing a compliant environment, Intersect's REDCap PaaS offering enables institutions to leverage REDCap for data collection and management. The PaaS solution represents an effective way for these institutions to utilise REDCap's capabilities while addressing their specific IT support challenges. This presentation will delve into the details of the REDCap PaaS offering, demonstrating how it enables smaller institutions to harness the potential of this powerful tool.
The geometrical meaning of the Weitzenböck connection
Creators: name: Golovnev, Alexey
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the current literature, there are many discussions about the local Lorentz invariance of modified teleparallel gravity. This symmetry is obviously violated in the classical "pure tetrad" formulation of the theory, while it gets restored in the "fully covariant" approach. My claim is that, despite many heated discussions, the two formulations are just equivalent. And the purpose of this note is to argue that the local Lorentz invariance is not natural for the modified teleparallel theories at all, making the pure tetrad approach more fundamentally justified.
description: 8 pages; minor additions
Anticancer & Anti mutagenic Properties of Medicinal Plants
Creators: name: HK Garg
name: Choudhary, Ashish
Publisher: name: figshare
Year: 2018
Subjects: Biotechnology

description: Cancer represents a substantial burden of disease in the community and appears to be a prime cause of concern. Every year over 200,000 people are diagnosed with cancer in the United Kingdom only, and approximately 120,000 die as an aftermath of the disease. According to the International Agency for Research on Cancer, in 2002, cancer killed > 6.7 million people around the world and another 10.9 million new cases were diagnosed. If the results are extrapolated, at the same rate, an estimated 15 million people will have cancer, annually, by 2020.According to an estimate given by American Cancer Society (2009), about 1,500,000 new cases and over 500,000 deaths are expected in the US by 2009. The National Cancer Registry of South Africa has spotted the cancers of bladder, colon, breast, cervix, lungs and melanoma commonly among inhabitants (Mqoqi et al., 2004). Attempts are underway to work out the therapeutic and anti-neoplastic properties of medicinal plants. Even as per the oldest and absolute system of medicine, Ayurveda, medicinal plants have therapeutic potential owing to the presence of natural antioxidants functioning as reducing agents, free radical scavengers and quenchers of singlet oxygen. Majority of their antioxidant activity is due to bioactive compounds viz. flavones, isoflavones, flavonoids, anthocyanins, coumarins, lignans, catechins and isocatechins. The present communication embraces the phytochemical and pharmacological studies on different parts of plants. The observations support the potential of certain medicinal plants Aegle marmelos, Aloe barbadensis, Bacopa monnieri andWithania somnifera as substitute anticancer drugs.
Classifying the age of a glass based on structural properties: A machine learning approach
Creators: name: Janzen, Giulia
name: Smit, Casper
name: Visbeek, Samantha
name: Debets, Vincent E.
name: Luo, Chengjie
name: Storm, Cornelis
name: Ciarella, Simone
name: Janssen, Liesbeth M. C.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: It is well established that physical aging of amorphous solids is governed by a marked change in dynamical properties as the material becomes older. Conversely, structural properties such as the radial distribution function exhibit only a very weak age dependence, usually deemed negligible with respect to the numerical noise. Here we demonstrate that the extremely weak age-dependent changes in structure are in fact sufficient to reliably assess the age of a glass with the support of machine learning. We employ a supervised learning method to predict the age of a glass based on the system's instantaneous radial distribution function. Specifically, we train a multilayer perceptron for a model glassformer quenched to different temperatures, and find that this neural network can accurately classify the age of our system across at least four orders of magnitude in time. Our analysis also reveals which structural features encode the most useful information. Overall, this work shows that through the aid of machine learning, a simple structure-dynamics link can indeed be established for physically aged glasses.