cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary Material from Using network analysis to study behavioural phenotypes: an example using domestic dogs
Creators: name: Goold, Conor
name: Vas, Judit
name: Olsen, Christine
name: Newberry, Ruth C.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Phenotypic integration describes the complex interrelationships between organismal traits, traditionally focusing on morphology. Recently, research has sought to represent behavioural phenotypes as composed of quasi-independent latent traits. Concurrently, psychologists have opposed latent variable interpretations of human behaviour, proposing instead a network perspective envisaging interrelationships between behaviours as emerging from causal dependencies. Network analysis could also be applied to understand integrated behavioural phenotypes in animals. Here, we assimilate this cross-disciplinary progression of ideas by demonstrating the use of network analysis on survey data collected on behavioural and motivational characteristics of police patrol and detection dogs (Canis lupus familiaris). Networks of conditional independence relationships illustrated a number of functional connections between descriptors, which varied between dog types. The most central descriptors denoted desirable characteristics in both patrol and detection dog networks, with ‘Playful’ being widely correlated and possessing mediating relationships between descriptors. Bootstrap analyses revealed the stability of network results. We discuss the results in relation to previous research on dog personality, and benefits of using network analysis to study behavioural phenotypes. We conclude that a network perspective offers widespread opportunities for advancing the understanding of phenotypic integration in animal behaviour.
Tagungsbericht: 7. QualiZüri Networking Day für qualitativ Sozialforschende
Creators: name: Lang, Sandra
name: Seibert, Daniela
Publisher: name: ETH Zurich
Year: 2019
Subjects: Interdisziplinarität
Transdisziplinarität
Forschungswerkstatt
Pragmatismus
Grounded-Theory-Methodologie
Ethnografie
Datenarchivierung
Digitalisierung
Forschungspolitik

description: Die heterogene und schweizweit wenig institutionalisierte Nachwuchs-Community der qualitativen Sozialforschung hat sich im vergangenen Jahr zum siebten Male in Zürich getroffen, um aktuelle Herausforderungen und Debatten zu diskutieren. Diesmal widmete sich die Veranstaltung Fragen der Bedeutung von Interdisziplinarität in der qualitativen Forschung bezüglich der Übersetzung zwischen Fachsprachen sowie Methoden, Konzepten und Theorien. Leitfragen dabei waren: Was bedeutet der gesteigerte Zulauf zur qualitativen Sozialforschung ohne parallele Institutionalisierung in Bezug auf die Qualitätssicherung? Welche Chancen und Risiken ergeben sich? Welche Potenziale folgen aus der Annäherung verschiedener Traditionen und Disziplinen im Forschungsprozess? Die Teilnehmenden des Networking Day kamen zu dem Schluss, dass qualitative Sozialforschung Herausforderungen genereller wissenschaftspolitischer Trends ausgesetzt ist. Es tun sich dabei einerseits Chancen für eine vermehrten Etablierung qualitativer Forschung in interdisziplinären Kontexten auf, andererseits besteht für Wissenschaftler/innen in der Qualifikationsphase die Gefahr, eine eindeutige fachliche Positionierung zu verlieren und "zwischen die Stühle" der akademischen Communities zu fallen.
description: Forum Qualitative Sozialforschung, 20 (2)
title: 05 – Entretien avec Zäwalä Bogalä : chant zäläsäña
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: chant
subject: ras Gugsa
subject: Tewodros
valueUri: ark:/12148/cb119723416
subject: Yohannes IV

description: Chant zäläsäña sur la mort des grands du XIXe siècle (ras Gugsa, Tewodros, Yohannes IV).
title: INNOVATION CAPITALISATION OF RESEARCH ANDTECHNOLOGY ORGANISATIONS - Strategic Recommendations for the AIT Austrian Institute of Technology GmbH
Creators: name: Jahn, Marcus
Publisher: name: TU Wien
Year: 2020
Subjects: subject: Research and Technology Organisations (RTO)
subject: innovation appropriation
subject: EU innovation system
subject: AIT Austrian Institute of Technology GmbH

description: Research and Technology Organisations (RTOs) have long been a critical part of any nation’s innovation system as a direct mediator between academic research and industrial development. Therefore, they have been a key to commercialisation of many innovations. A rapidly changing globalised economy and society have had an impact on national and international innovation systems, and as a result directly influenced strategies of RTOs. In particular the commercialisation of new innovations by means of licencing, supporting start-up and spin-off companies, has caused a paradigm shift of many European RTOs towards creating a supporting environment for such structures. This has become a vital instrument in supporting their national economies, in remaining relevant internationally and in adding value to the society by creating jobs directly or indirectly (Vivas, 2016). The AIT Austrian Institute of Technology GmbH is one of such European RTOs and also the largest in Austria. This project work has been tasked with investigating better strategies for the AIT for commercialising IP and internally generated knowledge. Therefore, it has analysed specifically the currently present commercialisation strategies of the AIT and has derived recommendations for better appropriation schemes for the organisation. A comparison to successful RTOs in Europe, such as Fraunhofer and Sintef, has shown the potential areas of improvement in particular with respect to spin-off strategies and engagement with start-ups. The shortfall of AIT’s present implementation of commercialisation strategies has been identified in the lack of support structure for knowledge transfer activities and entrepreneurship, both internal as well as external. The recommended strategies have been generalised on the one hand, since they have been found to be applicable to RTOs across the European innovation landscape, but also a closer look has been taken onto the sector of energy storage systems, which is a currently growing field of R&D and commercial interest. This has been done in manner of adding specific actions recommended to one area of research within AIT, since it has, like most RTOs, a broad range of activities across several fields, which all have their specific character and intrinsic nature which calls for a variation of appropriation schemes.
title: IT Reeingeneering for Growing Organizations. Exploiting the Full Potential of Digitalization in Developing and Manufacturing Companys
Creators: name: Kügerl, Thomas
Publisher: name: TU Wien
Year: 2020
Subjects: subject: IT
subject: Digital Transformation
subject: Digitalization
subject: Organization
subject: Reorganization
subject: Bimodal
subject: Structureless Organization
subject: Process
subject: Agile
subject: Scalability
subject: Structure
subject: DevOps
subject: Lean
subject: Optimization

description: Organizations today must face the challenges and potentials of digital transformation globally. The increasing speed at which newer and better still digital technologies are emerging is forcing managers to design organizations accordingly. On the one hand, new business models must be created to meet customer demandswhileon the other hand, internal processes and areas using information technologies need to be rethought. To be successful in a volatile environment, flexible organizational designs are a basis to remain competitive and develop competitive advantages.This thesis shows traditional and modern methods, processes, and also structures which allow small and medium-sized organizations to reorganize their rigid hierarchical and proven procedures when it comes to information technology. The first step in a multi-phase reorganizationof IT departments using the most appropriate methods and tools was developed throughout this thesis. The applied structure, processes, and tools shall benefit LOGICDATA’s first steps on their wayto become a digitalization champion in process digitalization and IT. The model is designed to meet the requirements of both traditional and modern IT environments. Modern,less hierarchical structures are combined with traditional forms. Finally, an outlook on structureless organizational designs is provided to make the purpose of the department a top priority where talents, experience and personal attitudes of the team specify the future journey. The first phase of the developed organizational design has been introduced in the case of LOGICDATA and evaluated by the author. The new approaches to structure, tools and processes havebeen compared to positive and negative aspects of the status quo before the organizational redesign. The results provide improvements and limitations the model has in its evaluated environment.The thesis was written in times of the global pandemic crisis due to coronavirus disease (COVID-19). In this paper,less hierarchical structures show the likelihood to adapt faster to such environmental changes compared to others.
Figure S4 from Interplay between RNA interference and heat shock response systems in Drosophila melanogaster
Creators: name: S. Yu. Funikov
name: S. S. Ryazansky
name: A. A. Kanapin
name: M. D. Logacheva
name: A. A. Penin
name: A. V. Snezhkina
name: V. Yu. Shilova
name: D. G. Garbuz
name: M. B. Evgen'ev
name: O. G. Zatsepina
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Relative expression level of miRNA biogenesis pathway genes after HS in hsp70- A) and yw B) strains. * P ≤ 0.05 versus control mRNA levels; mean values ± error bars for 3 replicates are represented.
Modelling of cirrus clouds – Part 1a: Model description and validation
Creators: name: Spichtinger, Peter
name: Gierens, Klaus M.
Publisher: name: ETH Zurich
Year: 2008

description: A double–moment bulk microphysics scheme for modelling cirrus clouds including ex-plicit impact of aerosols on different types of nucleation mechanism is described. Pro-cess rates are formulated in terms of generalised moments of the underlying a priorisize distributions in order to allow simple switching between various distribution types.5The scheme has been implemented into a simple box model and into the anelastic non-hydrostatic model EULAG. The new microphysics is validated against simulations withdetailed microphysics for idealised process studies and for a well documented case ofarctic cirrostratus. Additionally, the formation of ice crystals with realistic backgroundaerosol concentration is modelled and the effect of ambient pressure on homogeneous10nucleation is investigated in the box model. The arctic cirrostratus case study is alsosupplemented with sensitivity studies including different vertical velocities, temperaturefluctuations and wind shear. The model stands all tests and is thus suitable for cloud–resolving simulations of cirrus clouds. Last but not least, some new results are shown,corroborating the importance of sedimentation and dynamics inside cirrus clouds for15forming the structure of the cirrus.
description: Atmospheric Chemistry and Physics Discussions, 8 (1)
description: ISSN:1680-7375
description: ISSN:1680-7367
Scoping Review of Interventions to Reduce Edible Animal Product Usage
Creators: name: Mendez, Samara
name: Stevenson, Ben
name: Peacock, Jacob Robert
name: Mathur, Maya
name: Anderson, Jo
name: Hope, Jessica Elizabeth
name: Coni Arevalo
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Animal Studies
subject: Environmental Studies
subject: Social and Behavioral Sciences
subject: Food Studies

description: The excessive production and consumption of edible animal products (EAPs) like meat, eggs, dairy and fish is linked to numerous societal harms. The literature on interventions to reduce EAPU is large and increasingly mature, but difficult to access. In this review, we will aim to address this issues with broad inclusion criteria and an up-to-date search that includes a wide array of sources of both peer-reviewed and gray literature. Furthermore, we will provide an overview of which interventions to reduce EAPU have been studied and a rough assessment of the risk-of-bias in those studies. This will then provide an evidence base from which to identify promising interventions and to coordinate further study.
Characterizing random complex biological media by quantifying ultrasound multiple scattering
Creators: name: Egan, Thomas
name: Zhu, Yong
name: Geithner, Haley
name: Yao, Shanshan
name: Ali, Mir
name: Muller, Marie
name: Montgomery, Stephanie
name: Yousefian, Omid
name: Dashti, Azadeh
name: Karbalaeisadegh, Yasamin
name: Blackwell, John
Publisher: name: Frontiers
Year: 2025

description:
Introduction: In this in silico, in vitro, and in vivo study, we propose metrics for the characterization of highly scattering media using backscattered acoustic waves in the MHz range, for application to the characterization of biological media. Methods: Multi-element array transducers are used to record the ultrasonic Inter element Response Matrix (IRM) of scattering phantoms and of lung tissue in rodent models of pulmonary fibrosis. The distribution of singular values of the IRM in the frequency domain is then studied to quantify the multiple scattering contribution. Numerical models of scattering media, as well as gelatin-glass bead and polydimethylsiloxane phantoms with different scatterer densities, are used as a first step to demonstrate the proof of concept. Results: The results show that changes in microstructure of a complex random medium affect parameters associated with the distribution of singular values. Two metrics are proposed: E ( X ) , which is the expected value of the singular value distribution, and λ max , the maximum value of the probability density function of the singular value distribution, i.e., the most represented singular value. After validation of the methods in silico and in phantoms, we show that these metrics are relevant to evaluate pulmonary fibrosis in an in vivo rodent study on six control rats and eighteen rats with varying degrees of severity of pulmonary fibrosis. In rats, a moderate correlation was found between the severity of pulmonary fibrosis and metrics E ( X ) and λ max . Discussion: These results suggest that such parameters could be used as metrics to estimate the amount of multiple scattering in highly heterogeneous media, and that these parameters could contribute to the evaluation of structural changes in lung microstructure.
Figure S2 from Interplay between RNA interference and heat shock response systems in Drosophila melanogaster
Creators: name: S. Yu. Funikov
name: S. S. Ryazansky
name: A. A. Kanapin
name: M. D. Logacheva
name: A. A. Penin
name: A. V. Snezhkina
name: V. Yu. Shilova
name: D. G. Garbuz
name: M. B. Evgen'ev
name: O. G. Zatsepina
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Detailed analysis of the miRNA expression in D. melanogaster after HS. A-C) Context of miRNAs belonging to classes #1 and #2 (for a description of the classes of HS-responsive miRNAs see the text), and dynamics of the appearance and disappearance of differentially expressed miRNAs after HS presented as heatmaps
title: 07 – Entretien avec Zäwalä Bogalä : chant kebrité (chant de femme)
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: chant

description: Exemple d’ancien chant kebrité, réservé aux femmes.
title: A study on comprehensive fiber-optic expansion in rural areas
Creators: name: Krenmair, Matthias
Publisher: name: TU Wien
Year: 2020
Subjects: subject: Industry 4.0
subject: Digital Customs
subject: Customs Data
subject: Customs Automation
subject: Smart Supply Chain
subject: Advanced technologies in Customs
subject: Disruptive Technologies in Customs
subject: Internet of Things (IoT)
subject: Artificial Intelligence (AI)
subject: Augmented Reality (AR)
subject: Virtual Reality (VR) and Mixed Reality
subject: Blockchain
subject: Biometrics
subject: Drones (UAV)
subject: Information and Communication Technology (ICT)
subject: Electronic Data Interchange (EDI)
subject: Inspection and Detection Systems
subject: Non Intrusive Inspection (NII)

description: Information and communication technologies are an important driver of economic growth. It is in the interest of the European Union and national decision-makers to form a knowledge and information society. With the aim of creating a holistic European information society, actions must be taken against the "digital gap", the gap between urban and rural areas in particular. In order to master the fundamental technological changes, forward-looking political actions are required. It calls for political convergence and a willingness to adapt to the regulatory environment so that it is feasible to meet the changing needs of the digital economy. The main purpose of this thesis is to support municipalities, planning offices and companies that build empty pipework in their actions to form a suitable information society. Since there are a variety of empty pipe systems and components on the market, the choices are not easy. This paper identifies the most commonly used solutions with an additional goal to achieve a certain degree of standardization, in order to facilitate cooperation between infrastructure owners and network operators. The structure of this paper follows, in addition to the legal and political aspects, its attempts to cover the actual status of the broadband supply on a worldwide and European level, contains clarification of important technology standards in this industry, leads to the most commonly used solutions of the various installation methods in the trench and trenchless sector in order to ensure an efficient and cost-effective installation in rural areas. At the end of this paper, a profound planning guideline was drawn up, with the aim to support already existing and potential infrastructure architects. This planning guideline has the potential to prevent the people responsible from numerous planning errors, which will result in a decrease of the overall project costs and thereby increase the chances of future project realizations even in less populated areas.
Figure S1 from Interplay between RNA interference and heat shock response systems in Drosophila melanogaster
Creators: name: S. Yu. Funikov
name: S. S. Ryazansky
name: A. A. Kanapin
name: M. D. Logacheva
name: A. A. Penin
name: A. V. Snezhkina
name: V. Yu. Shilova
name: D. G. Garbuz
name: M. B. Evgen'ev
name: O. G. Zatsepina
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: The analysis of the miRNA expression patterns of the used datasets revealed that biological replicates are clustered together. A) Heatmap based on pairwise Spearman correlation of miRNA expression with using of Euclidean distance and complete linkage as distance measure and clustering method, respectively. B) Two-dimensional plot of first two principal components calculated by performing PCA of the transposed log-transformed RPM values of miRNA expression after removal of non-expressed and invariant miRNAs
Short-term variations of three rock glaciers and their relationship with meteorological conditions
Creators: name: Wirz, Vanessa
name: Gruber, Stephan
name: Purves, Ross S.
name: Beutel, Jan
name: Gärtner-Roer, Isabelle
name: Gubler, Stefanie
name: Vieli, Andreas
Publisher: name: ETH Zurich
Year: 2015

description: In recent years, strong variations in the speed of rock glaciers have been detected,raising questions about their stability in a changed climate. In this study, we present continuous time series over three years of surface velocities of six GPS stations located on three rock glaciers in Switzerland. Intra-annual velocity variations are analyzed in relation to local meteorological factors, such as precipitation, snow(melt), as well as air and ground surface temperatures. A main focus of this study lies on the abrupt velocity peaks, which have been detected at two steep and fast moving rock glacier tongues.The continuous measurements with high temporal resolution revealed that all rock glaciers experience clear intra annual variations in movement where the timing and the amplitude is rather similar between individual years. The seasonal decrease in velocity was typically smooth, starting one to three months after the seasonal decrease in temperatures, and was stronger in years with colder temperatures in mid winter. The seasonal acceleration always started during the zero curtain period, often was abrupt and rapid compared to the winter deceleration, and at two stations it was interrupted by short velocity peaks, occurring immediately after high water input from snow melt or heavy precipitation. The findings of this study suggest that both, the seasonal acceleration and the short velocity peaks are strongly influenced by water infiltration, causing thermal advection and increase in pore water pressure, and that likely no velocity peak was solely caused by high temperatures. In contrast, the amount of deceleration in winter seems to be mainly controlled by winter temperatures.
description: Earth Surface Dynamics Discussions, 3 (2)
description: ISSN:2196-6338
Figure S3 from Interplay between RNA interference and heat shock response systems in Drosophila melanogaster
Creators: name: S. Yu. Funikov
name: S. S. Ryazansky
name: A. A. Kanapin
name: M. D. Logacheva
name: A. A. Penin
name: A. V. Snezhkina
name: V. Yu. Shilova
name: D. G. Garbuz
name: M. B. Evgen'ev
name: O. G. Zatsepina
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Gene ontology of predicted target genes of miRNAs levelled by HS. A-G) GO enrichment analysis of unique, shared and common targets of levelled miRNAs after HS observed in all pairs of comparison. (1) Treemap view of GO terms, as a proportion of the genes having the corresponding GO term shows a two-level hierarchy of GO terms. Each rectangle corresponds to a single cluster representative collected into a high-level group according to semantic similarity of these GO terms. The representatives of loosely related terms are marked with different colours. The size of the rectangles reflects the P-value. (2) Graph view of GO terms. Colour of the node indicates the log10 of the adjusted P-value (BH correction). The size of node indicates the proportions of genes having corresponding GO term. The width of the edges indicates the number of genes sharing both related GO terms. Only GO terms which consist of at least 10% of miRNA targeted genes with a P-value ≤ 0.05 were took into consideration. Figures were made by REVIGO software after redundancy reduction of GO terms
Understanding flood regime changes in Europe: A state of the art assessment
Creators: name: Hall, Julia
name: Arheimer, Berit
name: Borga, Marco
name: Brázdil, Rudolf
name: Claps, Pierluigi
name: Kiss, Andrea
name: Kjeldsen, Thomas R.
name: Kriauĉuniene, J.
name: Kundzewicz, Zbigniew W.
name: Lang, Michel
name: Llasat, Maria C.
name: Macdonald, Neil
name: McIntyre, Neil R.
name: Mediero, Luis
name: Merz, Bruno
name: Merz, Ralf
name: Molnar, Peter
name: Montanari, Alberto
name: Neuhold, Clemens
name: Parajka, Juraj
name: Perdigão, Rui A.P.
name: Plavcová, Lenka
name: Rogger, Magdalena
name: Salinas, José L.
name: Sauquet, Eric
name: Schär, Christoph M.
name: Szolgay, Jan
name: Viglione, Alberto
name: Blöschl, Günter
Publisher: name: ETH Zurich
Year: 2013

description: Losing streams that are influenced by wastewater treatment plant effluents and combined sewer overflows (CSOs) can be a source of groundwater contamination. Released micropollutants such as pharmaceuticals, endocrine disrupters and other ecotoxicologically relevant substances as well as inorganic wastewater constituents can reach the groundwater, where they may deteriorate groundwater quality. This paper presents a method to quantify exfiltration mass flow rates per stream length unit Mex of wastewater constituents from losing streams by the operation of integral pumping tests (IPTs) up- and downstream of a target section. Due to the large sampled water volume during IPTs the results are more reliable than those from conventional point sampling. We applied the method at a test site in Leipzig (Germany). Wastewater constituents K+ and NO3− showed Mex values of 1241 to 4315 and 749 to 924 mg mstream−1 d−1, respectively, while Cl− (16.8 to 47.3 g mstream−1 d−1) and SO42− (20.3 to 32.2 g mstream−1 d−1) revealed the highest observed Mex values at the test site. The micropollutants caffeine and technical-nonylphenol were dominated by elimination processes in the groundwater between upstream and downstream wells. Additional concentration measurements in the stream and a connected sewer at the test site were performed to identify relevant processes that influence the concentrations at the IPT wells.
description: Hydrology and Earth System Sciences Discussions, 10 (12)
description: ISSN:1812-2116
description: ISSN:1812-2108
Sup. Figures 1-2 from Analysis of Drosophila p8 and p52 mutants reveals distinct roles for the maintenance of TFIIH stability and male germ cell differentiation
Creators: name: Grisel Cruz-Becerra
name: Juárez, Mandy
name: Valadez-Graham, Viviana
name: Zurita, Mario
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology

description: Figure S1. Relative expression levels of tTAFs and tMAC target genes in p8-depleted testes. Figure S2. DEGs relative to wild type that showed opposite behave in p8 versus p52 mutant testes.
title: Monitoring of different metabolic states of Sacchoromyces cerevisiae via NIR spectroscopy at low biomass concentration
Creators: name: Haderer, Markus
Publisher: name: TU Wien
Year: 2020
Subjects: subject: PAT
subject: Spectral Processing
subject: S.cerevisiae
subject: Multivariate Data-Analysis

description: Microorganisms, such as the yeast Saccharomyces cerevisiae, are used in fermentations in biotechnology to produce a wide variety of products - from beer to medicines. These industrial bioprocesses are subject to strict legal guidelines that require monitoring of the quality and quantity of the individual products. These controls are followed up with samples from the process. However, on-line sampling is a loss of biomass and/or product, there is a risk of contamination of the process, and the preparation of the samples is very time-consuming. On-line measurements via spectroscopic methods can provide a lot of data in real time without touching or disturbing the contents of the bioreactor.With the help of NIR data from fermentations from 2016 and 2019, analyses of the metabolism of the yeast were made at a biomass concentration of less than or equal 2.5g/L.The fermentations were exposed to dierent process conditions. On the one hand, standard fermentations were carried out in which the best possible conditions for the yeasts were set. In the following analyses, these served as target values for an ideally running process. Furthermore, various disturbance processes were recorded in which the environment of the yeast (the medium) was deviated into a sub-optimal range. Too much or too little base was added so that the pH affected the metabolism, or the oxygen supply was interrupted to force a change to the anaerobic metabolism. These disturbances should simulate realistic failures of individual parameters in the industry. The results obtained were processed using the R software and analysed using PCA. Off-line samples served as controls for the present metabolism.The results from the spectral data showed that a statement about the respective metabolism can be made. The standard fermentations can be distinguished from the disturbed fermentations as well as the disturbed processes among each other. A comparison with data recorded in 2016 gave similar results with regard to the physiological data. The spectral data from 2016 and 2019 gave different results, but there was insufficient data to give an exact reason for the origin of this deviation.If the results of the 2019 data are reproducible through further fermentations, a model for the detection of deviations can be created. Furthermore, it can be determined - by increased time sampling - how early a difference from the optimum can be recognized. Depending on the result of the trend over time, an earlier intervention would be possible if there was a signicant deviation in the suboptimal running process.
Water vapor δ2H and δ18O measurements using off-axis integrated cavity output spectroscopy
Creators: name: Sturm, Patrick
name: Knohl, Alexander
Publisher: name: ETH Zurich
Year: 2009

description: We present a detailed assessment of a commercially available water vapor isotopeanalyzer (WVIA, Los Gatos Research, Inc.) for simultaneous in-situ measurements ofδ2H andδ18O in water vapor. This method, based on off-axis integrated cavity outputspectroscopy, is an alternative to the conventional water trap/isotope ratio mass spectrometry (IRMS) techniques. We evaluate the analyzer in terms of precision, memoryeffects, concentration dependence, temperature sensitivity and long-term stability. Acalibration system based on ink jet technology is used to characterize the performanceand to calibrate the analyzer. Our results show that the precision at an averagingtime of 15 s is 0.16‰ forδ2H and 0.08‰ forδ18O. The isotope ratios are strongly dependent on the water mixing ratio of the air. Taking into account this concentrationdependence as well as the temperature sensitivity of the instrument we obtained along-term stability of the water isotope measurements of 0.38‰ forδ2H and 0.25‰forδ18O. The accuracy of the WVIA was further assessed by comparative measure-ments using IRMS and a dew point generator indicating a linear response in isotopic composition and H2O concentrations. The WVIA combined with a calibration systemprovides accurate high resolution water vapor isotope measurements and opens newpossibilities for hydrological and ecological applications
description: Atmospheric Measurement Techniques Discussions, 2 (4)
description: ISSN:1867-8610
Untargeted Metabolomics Reveals Acylcarnitines as Major Metabolic Targets of Resveratrol in Breast Cancer Cells
Creators: name: Rushing, Blake R.
name: Falcone, Isabella G.
Publisher: name: MDPI
Year: 2025

description:
Background/Objectives: Millions of new diagnoses of breast cancer are made each year, with many cases having poor prognoses and limited treatment options, particularly for some subtypes such as triple-negative breast cancer. Resveratrol, a naturally occurring polyphenol, has demonstrated many anticancer properties in breast cancer studies. However, the mechanism of action of this compound remains elusive, although prior evidence suggests that this compound may work through altering cancer cell metabolism. Our objective for the current study was to perform untargeted metabolomics analysis on resveratrol-treated breast cancer cells to identify key metabolic targets of this compound. Methods: MCF-7 and MDA-MB-231 breast cancer cells were treated with varying doses of resveratrol and extracted for mass spectrometry-based untargeted metabolomics. Data preprocessing and filtering of metabolomics data from MCF-7 samples yielded 4751 peaks, with 312 peaks matched to an in-house standards library and 3459 peaks matched to public databases. Results: Pathway analysis in MetaboAnalyst identified significant (p < 0.05) metabolic pathways affected by resveratrol treatment, particularly those involving steroid, fatty acid, amino acid, and nucleotide metabolism. Evaluation of standard-matched peaks revealed acylcarnitines as a major target of resveratrol treatment, with long-chain acylcarnitines exhibiting a 2–5-fold increase in MCF-7 cells and a 5–13-fold increase in MDA-MB-231 cells when comparing the 100 µM treated cells to vehicle-treated cells (p < 0.05, VIP > 1). Notably, doses below 10 µM showed an opposite effect, possibly indicating a biphasic effect of resveratrol due to a switch from anti-oxidant to pro-oxidant effects as dose levels increase. Conclusions: These findings suggest that resveratrol induces mitochondrial metabolic reprogramming in breast cancer cells in a dose-dependent manner. The biphasic response indicates a potential optimal dosage for therapeutic effectiveness. Further research is warranted to explore the mechanisms underlying these metabolic alterations and their implications for precision nutrition strategies in cancer treatment.
Impact of parametric uncertainties on the present-day climate and on the anthropogenic aerosol effect
Creators: name: Lohmann, Ulrike
name: Ferrachat, Sylvaine
Publisher: name: ETH Zurich
Year: 2010

description: Clouds constitute a large uncertainty in global climate modeling and climate changeprojections as many clouds are smaller than the size of a model grid box. Some pro-cesses, such as the rates of rain and snow formation that have a large impact onclimate, cannot be observed. These processes are thus used as tuning parameters in order to achieve radiation balance. Here we systematically investigate the impactof various tunable parameters within the convective and stratiform cloud schemes andof the ice cloud optical properties on the present-day climate in terms of clouds, radi-ation and precipitation. The total anthropogenic aerosol effect between pre-industrialand present-day times amounts to−1.00 Wm−2obtained as an average over all simulations as compared to−1.02 Wm−2from those simulations where the global annualmean top-of-the atmosphere radiation balance is within±1 Wm−2. The parametric un-certainty when taking all simulations into account has an uncertainty range of 25%between the minimum and maximum value. It is reduced to 11% when only the simu-lations with a balanced top-of-the atmosphere radiation are considered.
description: Atmospheric Chemistry and Physics Discussions, 10 (8)
description: ISSN:1680-7375
description: ISSN:1680-7367
First results from the GPS atmosphere sounding experiment TOR aboard the TerraSAR-X satellite
Creators: name: Beyerle, Georg
name: Grunwaldt, Ludwig
name: Heise, Stefan
name: Köhler, Wolfgang
name: König, Rolf
name: Michalak, Grzegorz
name: Rothacher, Markus
name: Schmidt, Torsten
name: Wickert, Jens
name: Tapley, Bryon D.
name: Giesinger, B.
Publisher: name: ETH Zurich
Year: 2010

description: GPS radio occultation events observed between 24 July and 17 November 2008 bythe IGOR occultation receiver aboard the TerraSAR-X satellite are processed and ana-lyzed. The comparison of 16 262 refractivity profiles with collocated ECMWF data yielda mean bias of−0.60% to+0.02% at altitudes between 5 and 30 km. Standard deviations decrease from about 0.8% to 1.8% at 5 km to about 0.5% to 0.8% at about 10kmaltitude. At low latitudes mean biases and standard deviations are larger, in particular inthe lower troposphere. The results are consistent with 15 159 refractivity observationscollected during the same time period by the BlackJack receiver aboard GRACE-Aand processed by GFZ’s operational processing system. The main difference between the two occultation instruments is the implementation of open-loop signal tracking inthe IGOR (TerraSAR-X) receiver which improves the tropospheric penetration depthin terms of ray height by about 2km compared to the conventional closed-loop dataacquired by BlackJack (GRACE-A).
description: Atmospheric Chemistry and Physics Discussions, 10 (11)
description: ISSN:1680-7375
description: ISSN:1680-7367
Bacteria in the ECHAM5-HAM global climate model
Creators: name: Petrus, Ana
name: Lohmann, Ulrike
name: Storelvmo, Trude
Publisher: name: ETH Zurich
Year: 2011

description: Bacteria are the most active naturally occuring ice nuclei (IN) due to the ice nucleationactive proteins on their surface, which serve as active sites for ice nucleation. Theirpotential impact on clouds and precipitation is not well known and needs to be inves-tigated. Bacteria as a new aerosol species were introduced into the global climate model (GCM) ECHAM5-HAM. The inclusion of bacteria acting as IN in a GCM leadsto only minor changes in cloud formation and precipitation on a global level, however,changes in the liquid water path and ice water path can be observed, specifically in theboreal regions where tundra and forests act as sources of bacteria.
description: Atmospheric Chemistry and Physics Discussions, 11 (1)
description: ISSN:1680-7375
description: ISSN:1680-7367
title: 08 – Entretien avec Zäwalä Bogalä
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: occupation italienne
valueUri: ark:/12148/cb11956728n

description: Sur la liberté de parole pendant l’occupation italienne.
Dust ice nuclei effects on cirrus clouds
Creators: name: Kuebbeler, Miriam
name: Lohmann, Ulrike
name: Hendricks, Johannes
name: Kärcher, Bernd
Publisher: name: ETH Zurich
Year: 2013

description: In order to study aerosol-cloud interactions in cirrus clouds we apply a new multiple-mode ice microphysical scheme to the general circulation model ECHAM5-HAM. Themultiple-mode ice microphysical scheme allows to analyse the competition betweenhomogeneous freezing of solution droplets, deposition nucleation of pure dust particles, immersion freezing of coated dust particles and pre-existing ice. We base thefreezing efficiencies of coated and pure dust particles on most recent laboratory data.The effect of pre-existing ice, which was neglected in previous ice nucleation param-eterizations, is to deplete water vapour by depositional growth and thus prevent ho-mogeneous and heterogeneous freezing from occurring. In a first step, we extensively tested the model and validated the results against in-situ measurements from vari-ous aircraft campaigns. The results compare well with observations; properties like icecrystal size and number concentration as well as supersaturation are predicted withinthe observational spread.We find that heterogeneous nucleation on mineral dust particles and the consideration of pre-existing ice in the nucleation process may lead to significant effects: globally,ice crystal number and mass are reduced by 10% and 5%, whereas the ice crystalssize is increased by 3%. The reductions in ice crystal number are most pronouncedin the tropics and mid-latitudes on the Northern Hemisphere. While changes in the mi-crophysical and radiative properties of cirrus clouds in the tropics are mostly driven by considering pre-existing ice, changes in the northern hemispheric mid-latitudes mainlyresult from heterogeneous nucleation. The so called negative Twomey-effect in cirrusclouds is represented in ECHAM5-HAM. The net change in the radiation budget is−0.94 Wm−2, implying that both, heterogeneous nucleation on dust and pre-existingice have the potential to modulate cirrus properties in climate simulations and thus should be considered in future studies.
description: Atmospheric Chemistry and Physics Discussions, 13 (4)
description: ISSN:1680-7375
description: ISSN:1680-7367
Contributions from DMS and ship emissions to CCN observed over the summertime North Pacific
Creators: name: Phinney, Jackie
name: Leaitch, W. Richard
name: Lohmann, Ulrike
name: Shantz, N.C.
name: Worsnop, Douglas R.
Publisher: name: ETH Zurich
Year: 2009

description: Measurements of cloud condensation nuclei (CCN) made over the remote North Pa-cific Ocean in July 2002 are analysed with concurrent measurements of aerosol num-ber, mass and composition. Overall the CCN are controlled by the sulphate, includingone case of particle nucleation and growth resulting from dimethyl sulphide oxidation that enhanced CCN concentrations. Hourly CCN concentrations are correlated withconcentrations of sulphate plus methanesulphonic acid (MSA) over the entire studyperiod (r2=0.43 and 0.52 for supersaturations of 0.34 and 0.19%, respectively), andare not well correlated with other organics (r2<0.2). One case study reveals elevatedmass and number concentrations of ultrafine and fine organic particles due to regional ship emissions, during which organic mass concentrations (see Fig. 2). In Fig. 7c,the 80–90 nm particle concentrations are correlated with CCN values (r2=0.39 and0.46 for supersaturations of 0.19 and 0.34%, respectively). The evolution of the timeseries and mass distributions of organics, sulphate and MSA over this timeframe indi-cate that the regional distribution of small, diffuse ship-sourced organic particles act as condensation sites for sulphur species, resulting in a subsequent increase in numberconcentrations of CCN. Direct emissions of organic particles may exert a strong controlon marine CCN concentrations once diffused into the marine atmosphere by acting ascondensation sites for biogenic and anthropogenic sulphur species.
description: Atmospheric Chemistry and Physics Discussions, 9 (1)
description: ISSN:1680-7375
description: ISSN:1680-7367
Exploiting the weekly cycle as observed over Europe to analyse aerosol indirect effects in two climate models
Creators: name: Quaas, Johannes
name: Boucher, Olivier
name: Jones, Andy
name: Kieser, Jens
name: Joos, Hanna
Publisher: name: ETH Zurich
Year: 2009

description: A weekly cycle in aerosol pollution and meteorological quantities is observed over Eu-rope. In the present study we exploit this effect to analyse aerosol-cloud-radiationinteractions. A weekly cycle is imposed on anthropogenic emissions in two generalcirculation models that include parameterizations of aerosol cycles and cloud micro-physics. It is found that the simulated weekly cycles in sulfur dioxide, sulfate, andaerosol optical depth in both models agree reasonably well with the observed onesindicating model skill in simulating the aerosol cycle. A distinct weekly cycle in clouddroplet number concentration is demonstrated in both observations and models. Forother variables, such as cloud liquid water path, cloud cover, top-of-the-atmosphere radiation fluxes, precipitation, and surface temperature, large variability and contradictoryresults between observations, model simulations, and model control simulations with-out a weekly cycle in emissions prevent us from reaching any firm conclusions aboutthe potential aerosol impact on meteorology or the realism of the modeled secondaerosol indirect effects.
description: Atmospheric Chemistry and Physics Discussions, 9 (3)
description: ISSN:1680-7375
description: ISSN:1680-7367
NATIONAL HOLIDAYS AND TRADITIONS, THEIR CHARACTERISTICS AND IMPORTANCE
Creators: name: Ahmedova, Nozimaxon
Publisher: name: Zenodo
Year: 2024

description: Holidays have become the most important and integral part of human life since ancient times. It is absolutely impossible to imagine human life without them. Holidays are a mirror that reflects the best and most beautiful aspects of people’s life. In this article, the national holidays of the Uzbek people, their unique customs and ceremonies, different views on their origin, what we celebrate and what our ancestors celebrated the stages of development of holidays are discussed.
Tables: SSP and ddPCR experiments (4 tables)
Creators: name: Tournay, Robert
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 310299
subject: Bioinformatics and computational biology not elsewhere classified

description: This file (.xlsx) contains four tables containing data from the development of the strain-specific primers and the ddPCR assay results:
Table S14. The SSP sets used in ddPCR to assess colonization, including the primer names, sequences, and parameters.Table S15. Development of SSP for ddPCR experiments. Names of Genera and number of genomes used in identifying unique DNA sequences.Table S16. Data from the ddPCR assaysTable S23. Estimation of target copies per gram of leaf tissue.
Objective assessment of ozone in chemistry-climate model simulations
Creators: name: Karpechko, Alexey Yu.
name: Gillett, Nathan P.
name: Hassler, Birgit
name: Rosenlof, Karen H.
name: Rozanov, Eugene
Publisher: name: ETH Zurich
Year: 2009

description: Stratospheric ozone recovery is expected to drive pronounced trends in atmospherictemperature and circulation from the stratosphere to the troposphere in the 21st cen-tury, but coupled chemistry-climate models (CCMs) vary widely in their predictions offuture ozone evolution. In order to assess which models might be expected to better simulate future ozone evaluation, we assess the ability of twelve CCMs to simulateobserved ozone climatology and trends and rank the models according to their errorsaveraged across the individual diagnostics chosen. According to our analysis no onemodel performs better than the others in all the diagnostics; however, combining errorsin individual diagnostics into one metric of model performance allows us to objectively rank the models. The multi-model average shows better overall agreement with theobservations than any individual model. Based on this analysis we conclude that themulti-model average ozone projection presents the best estimate of future ozone evolu-tion. Our results also demonstrate a sensitivity of the analysis to the choice of referencedata set for vertical ozone distribution over the Antarctic, highlighting the constraints that large observational uncertainty imposes on such model verification.
description: Atmospheric Chemistry and Physics Discussions, 9 (5)
description: ISSN:1680-7375
description: ISSN:1680-7367
title: couvercle Cv3a (Barrier  Luginbühl 2021)
Creators: name: Bibracte
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: couvercle

description: Couvercle à paroi convexe  lèvre à méplat horizontal parcouru par une cannelure (Source : Barrier  Luginbühl 2021)
title: 09 – Entretien avec Zäwalä Bogalä : chants mentionnant des chefs militaires de la période italienne
Creators: name: Wion, Anaïs
name: Bolay, Anne
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chant
subject: occupation italienne
valueUri: ark:/12148/cb11956728n

description: Chants relatifs à la période de l’occupation italienne.