cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Glass globular beaker
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: Glass squat jar (Harden Class VIII, b, 1). Height 10.3 cm, rim diam 5.2 cm. Glass light golden brown with fine air bubbles. Splayed rim, inward folded: swelling body with pushed-in omphalos base, with pontil mark. Decorated with narrow and shallow fluting from base to rim. Glass very thin, and whole vessel elegant and well-made. Rim shows only slight trace of wear.
sj-pdf-1-ome-10.1177_00302228211008748 - Supplemental material for ‘She Can’t Support Me Because She’s so Old’: A Mixed-Methods Study of Support Experiences and Needs in Adult Child–Parent Dyads at the End of Life
Creators: name: Herbst, Franziska A.
name: Gawinski, Laura
name: Schneider, Nils
name: Stiel, Stephanie
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-ome-10.1177_00302228211008748 for ‘She Can’t Support Me Because She’s so Old’: A Mixed-Methods Study of Support Experiences and Needs in Adult Child–Parent Dyads at the End of Life by Franziska A. Herbst Laura Gawinski, Nils Schneider and Stephanie Stiel in OMEGA—Journal of Death and Dying
Glass bead on a white-metal slip-knot ring
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: Black opaque glass bead, diam. 1.1cm, short barrel, with opaque white zig-zag trail marvered in, preserved with fragment of silver ring, broken in two and incomplete, diam c. 2.3 cm. with knotted twists, 2 on one side and 3 on the other.Mayer card attributes to Barfreston grave 32, and refers to Inventorium Sepulchrale p. 140, but no mention of this in text. No beads in grave. The bead from grave 34, on a ring, was red and white. The bead on pl. VII.11 from grave 34 looks very like, however, in size though it is red and white not black, and the ring is similar. Could the bead have changed colour, eg. during blitz. No card for any missing bead from this grave.
Glass globular beaker
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: The companion glass to M 6954 A. A pale golden brown fluted jar (Harden Class VIII, b, 2), perhaps slightly thinner and paler in colour, and broken in many places. Height 10.2 cm, rim diam. 5.5 cm. Rim slightly less smoothed, so inward fold shows more clearly. Glass more irridescent, rim only slightly worn.
Additional file 1 of Cervical cancer screening program in Indonesia: is it time for HPV-DNA tests? Results of a qualitative study exploring the stakeholders’ perspectives
Creators: name: Ekawati, Fitriana Murriya
name: Listiani, Putri
name: Idaiani, Sri
name: Thobari, Jarir At
name: Hafidz, Firdaus
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
EVALUACIÓN DEL IMPACTO EN LA UTILIZACIÓN DEL LIBRO DE CURSO EN EL RENDIMIENTO ACADÉMICO ESTUDIANTIL DE LA MATERIA DE CÁLCULO INTEGRAL, CARRERA DE INGENIERÍA AGRONÓMICA. UNIVERSIDAD CENTRAL DEL ECUADOR
Creators: name: Nicole Becerra Orosco, Nayely
Publisher: name: unknown
Year: 2023

description: El uso de los libros-guía son esenciales y muy importantes para nuestro aprendizaje. Contribuyen significativamente al mejoramiento del rendimiento académico en cualquier disciplina.
EVALUACIÓN DEL IMPACTO EN LA UTILIZACIÓN DEL LIBRO DE CURSO EN EL RENDIMIENTO ACADÉMICO ESTUDIANTIL DE LA MATERIA DE CÁLCULO INTEGRAL, CARRERA DE INGENIERÍA AGRONÓMICA. UNIVERSIDAD CENTRAL DEL ECUADOR
Creators: name: Nicole Becerra Orosco, Nayely
Publisher: name: Humanities Commons
Year: 2023

description: El uso de los libros-guía son esenciales y muy importantes para nuestro aprendizaje. Contribuyen significativamente al mejoramiento del rendimiento académico en cualquier disciplina.
Additional file 1 of Limited or complete? Teaching and learning conceptions and instructional environments fostered by STEM teaching versus research faculty
Creators: name: Rozhenkova, Veronika
name: Snow, Lauren
name: Sato, Brian K.
name: Lo, Stanley M.
name: Buswell, Natascha Trellinger
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. Syllabus assessment rubric.
Additional file 1 of “That’s just Future Medicine” - a qualitative study on users’ experiences of symptom checker apps
Creators: name: Müller, Regina
name: Klemmt, Malte
name: Koch, Roland
name: Ehni, Hans-Jörg
name: Henking, Tanja
name: Langmann, Elisabeth
name: Wiesing, Urban
name: Ranisch, Robert
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy

description: Supplementary Material 1: CHECK.APP User Interview Guide (English)
First Xeric'S E-Newsletter - December 2015
Creators: name: SOULA Guylène
Publisher: name: Zenodo
Year: 2015
Subjects: electric vehicle (EV)
Climate Control System (CCS)
Energy efficiency
dehumidification
hydrophobic membrane

description: This delivrable written in the frame of the XERIC project (WP5 - Impact and Exploitation) explains how the first e-newsletter was created and sent and what makes up the mailing lists. The content of the newsletter is then displayed, along with the coordinator’s full editorial. The e-newsletters were released twice a year to XERIC’s mailing list, to share news about the project and its activities (6 e-newsletters sent over the duration of XERIC, available on XERIC website and archived in ZENODO).
Unterlage Zu Workshop Ix: Forschungsmarketing; Präsentation Der Dfg
Creators: name: Bankamp, Dagmar
name: Gad, Gernot
Publisher: name: Zenodo
Year: 2017
Subjects: Forschungsmarketing, DFG

description: Präsentation der DFG zu den verschiedenen Unterstützungsmaßnahmen für ein Forschungsmarketing
Parallel Glosses, Shared Glosses, and Gloss Clustering: Can Network-Based Approach Help Us to Understand Organic Corpora of Glosses?
Creators: name: Stein(ova), Evina
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Social sciences--Network analysis
subject: Middle Ages
subject: Digital humanities
subject: Manuscripts
subject: Carolingians
subject: Diffusion of innovations
subject: Intellectual life--Historiography
subject: Manuscripts, Medieval
subject: Literature, Medieval

description: Glossing was an important element of medieval western manuscript culture. However, glosses are notoriously difficult to analyze because of their triviality, fluid nature, heterogeneity of origin, complex transmission histories, and anonymity. Traditional scholarly approaches such as close reading and the genealogical method often do not produce satisfactory results, especially in the case of gloss corpora that are highly organic, i.e., display the traits listed above to a significant degree. This article outlines a method for analyzing the organic corpora of glosses based on their treatment as networks. The theoretical model for the proposed method is the co-occurrence network, a network model in which relationships between entities (nodes) are established based on certain shared properties or constituent elements (edges). In the case of corpora of glosses, glossed manuscripts are assumed as nodes, and the glosses that specific manuscripts have in common constitute the edges between them. Since gloss parallelism can arise through different processes, including randomness, the article describes two strategies that reduce such noise so that the transmission of glosses can be effectively examined. The method is demonstrated on a representative corpus – the early medieval glosses to the first book of the Etymologiae of Isidore of Seville.
Additional file 1 of Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: synthesis, characterization, anticancer activity and antioxidant properties
Creators: name: Sayed, Eman M.
name: Bakhite, Etify A.
name: Hassanien, Reda
name: Farhan, Nasser
name: Aly, Hanan F.
name: Morsy, Salma G.
name: Hassan, Nivin A.
Publisher: name: figshare
Year: 2024
Subjects: Biophysics
Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer
Hematology

description: Additional file 1: Fig. S1. FT-IR spectrum of Compound 1. Fig. S2. 1H NMR spectrum of Compound 1. Fig. S3. 13C NMR spectrum of compound 1. Fig. S4. FT-IR spectrum of compound 3. Fig. S5. 1H NMR spectrum of compound 3. Fig. S6. 13C NMR spectrum of compound 3. Fig. S7. FT-IR spectrum of compound 4. Fig. S8. 1H NMR spectrum of compound 4. Fig. S9. 13C NMR spectrum of compound 4. Fig. S10. FT-IR spectrum of compound 5. Fig. S11. 1H NMR spectrum of compound 5. Fig. S12. 13C NMR spectrum of compound 5. Fig. S13. FT-IR spectrum of compound 6. Fig. S14. 1H NMR spectrum of compound 6. Fig. S15. 13C NMR spectrum of compound 6. Fig. S16. FT-IR spectrum of compound 7a. Fig. S17. 1H NMR spectrum of compound 7a. Fig. S18. 13C NMR spectrum of compound 7a. Fig. S19. FT-IR spectrum of compound 7b. Fig. S20. 1H NMR spectrum of compound 7b. Fig. S21. 13C NMR spectrum of compound 7b. Fig. S22. FT-IR spectrum of compound 7c. Fig. S23. 1H NMR spectrum of compound 7c. Fig. S24. 13C NMR spectrum of compound 7c. Fig. S25. FT-IR spectrum of compound 7d. Fig. S26. 1H NMR spectrum of compound 7d. Fig. S27. 13C NMR spectrum of compound 7d. Fig. S28. FT-IR spectrum of compound 7e. Fig. S29. 1H NMR spectrum of compound 7e. Fig. S30. 13C NMR spectrum of compound 7e. Fig. S31. FT-IR spectrum of compound 8a. Fig. S32. 1H NMR spectrum of compound 8a. Fig. S33. 13C NMR spectrum of compound 8a. Fig. S34. FT-IR spectrum of compound 8b. Fig. S35. 1H NMR spectrum of compound 8b. Fig. S36. 13C NMR spectrum of compound 8b. Fig. S37. FT-IR spectrum of compound 8c. Fig. S38. 1H NMR spectrum of compound 8c. Fig. S39. 13C NMR spectrum of compound 8c. Fig. S40. FT-IR spectrum compound 8d. Fig. S41. 1H NMR spectrum compound 8d. Fig. S42. 13C NMR spectrum of compound 8d. Fig. S43. FT-IR spectrum compound 8e. Fig. S44. 1H NMR spectrum compound 8e. Fig. S45. 13C NMR spectrum of compound 8e. Table S1. Raw date of toxicity and viability of compounds 1,3–6 against MCF7. Table S2. Raw date of toxicity and viability of compounds 7a–e against MCF7. Table S3. Raw date of toxicity and viability of compounds 8a–e against MCF7. Table S4. Raw date of toxicity and viability of compounds 1,3–6 against A549. Table S5. Raw date of toxicity and viability of compounds 7a–e against A549. Table S6. Raw date of toxicity and viability of compounds 8a–e against A549. Table S7. CDK2 inhibitor detailed results. Table S8. DHFR inhibitor detailed results. Table S9. Eef2 inhibitor detailed results. Table S10. IKB inhibitor detailed results. Table S11. RET inhibitor detailed results.
Copper-alloy mount
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: Inventorium Sepulchrale, page 41, note: \It somewhat resembles the Saxon and Frankish girdle ornaments in pl. LVI vol. ii Collectanea Antiqua; and such from the objects found with it I imagine it to have been.- C.R.S.\""Openwork bronze ornament, length 4.5 cm, with traces of tinning. Flat, cut into high-shoulder, broad skirted bell-shape, rather waisted, with square tab at top. Openwork pattern of two irregular half-circles at top, 4 triangles below. Single rivets at top and bottom, length 2mm. Certainly affixed to leather, probably a belt.
DIALÉTICA MATERIALISTA NA INTERDISCIPLINARIDADE:  UMA PERSPECTIVA NECESSÁRIA PARA A EDUCAÇÃO  AMBIENTAL
Creators: name: César Augusto Soares da Costa
Publisher: name: Zenodo
Year: 2012

description: Resumo Este trabalho aborda as relações entre a interdisciplinaridade e a dialética materialista a partir do debate ambiental crítico, histórico e complexo. Num primeiro momento, iremos expor as bases conceituais e metodológicas que estão estruturados o método dialético e seus vínculos com a interdisciplinaridade no debate ambiental. No segundo, abordaremos a relação entre interdisciplinaridade à luz do materialismo histórico-dialético. Por fim, apontaremos perspectivas assinalando quais implicações epistemológicas a dialética materialista relacionada com discussão interdisciplinar podem trazer à discussão ambiental contemporânea.   Palavras-chave: Educação Ambiental, Interdisciplinaridade, Dialética materialista.
Supplemental Material, sj-docx-1-jst-10.1177_01626434211003026 - Plugged In: Screen-Based Device Use Among U.S. Public School Speech-Language Pathologists and Associated Clinical Characteristics
Creators: name: Sauermilch, Willow
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Education
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental Material, sj-docx-1-jst-10.1177_01626434211003026 for Plugged In: Screen-Based Device Use Among U.S. Public School Speech-Language Pathologists and Associated Clinical Characteristics by Willow Sauermilch in Journal of Special Education Technology
Elixir Workshops Organized With The Rare  Disease Community
Creators: name: Gut, Ivo
name: Roos, Marco
name: Et Al.
Publisher: name: Zenodo
Year: 2017
Subjects: Rare disease
bioinformatics

description: In this report we describe the past and planned future workshops for the rare disease (RD) domain within the context of the ELIXIR-EXCELERATE project with the aims (1) to identify key training contacts/subjects in the RD community, (2) to identify specific training

needs in the RD community and (3) to spread specific knowledge needed in the RD community. An important mission of EXCELERATE WP8 ‘ELIXIR infrastructure for Rare Disease research’, defined at the kick-off meeting on November 24, 2015 in Leiden, is to help the rare disease community in different nodes to raise its infrastructure activities to the level of best practices in ELIXIR infrastructure, i.e. where rare disease data, metadata, tools, and catalogues are shared, interoperable, and sustainable at the source, conform a common set of principles and standards across participating countries/nodes and in agreement with the ELIXIR platforms. To achieve optimal knowledge exchange between the domains, workshops in this WP are typically co-organised with members from the rare

disease community and co-sponsored by relevant projects such as RD-Connect.

Events were either organised specifically with the Rare Disease (RD) community, or a separate stream/session for the RD community was co-organised around other events. Training workshops and courses were delivered in partnership with WP11 ‘EXCELERATE Training Programme’.

The delivery of workshops was complemented by the ELIXIR implementation study/RDConnect

proof-of-concept to test interoperability backbone components for enabling

queries across rare disease biobanks and registries.
Additional file 1 of Survival comparison of first-line treatment regimens in patients with braf-mutated advanced colorectal cancer: a multicenter retrospective study
Creators: name: Meng, Qianhao
name: Zhao, Jian
name: Yu, Yuanyuan
name: Wang, Ke
name: Ren, Jing
name: Xu, Chang
name: Wang, Yusheng
name: Wang, Guangyu
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. STROBE Statement—checklist of items that should be included in reports of observational studies.
sj-docx-1-pmj-10.1177_02692163211002045 – Supplemental material for Association between high cost user status and end-of-life care in hospitalized patients: A national cohort study of patients who die in hospital
Creators: name: Quinn, Kieran L
name: Hsu, Amy T
name: Meaney, Christopher
name: Qureshi, Danial
name: Tanuseputro, Peter
name: Hsien Seow
name: Webber, Colleen
name: Fowler, Rob
name: Downar, James
name: Goldman, Russell
name: Chan, Raphael
name: McGrail, Kimberlyn
name: Isenberg, Sarina R
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-pmj-10.1177_02692163211002045 for Association between high cost user status and end-of-life care in hospitalized patients: A national cohort study of patients who die in hospital by Kieran L Quinn, Amy T Hsu, Christopher Meaney, Danial Qureshi, Peter Tanuseputro, Hsien Seow, Colleen Webber, Rob Fowler, James Downar, Russell Goldman, Raphael Chan, Kimberlyn McGrail and Sarina R Isenberg in Palliative Medicine
Induced fit or conformational selection? The case of Na,K-ATPase Pi binding
Creators: name: Faraj, Santiago E.
name: Rossi, Rolando C.
name: Montes, Mónica R.
Publisher: name: F1000Research
Year: 2017

description: Ligand binding by macromolecules is crucial for a multitude of physiological processes. In virtually all cases, binding of ligands and conformational changes go hand in hand. The two limiting cases are the induced fit mechanism, in which ligand binding occurs before conformational change, and conformational selection, where the conformational change occurs before ligand binding. It was pointed out that induced fit is the most commonly documented mechanism of recognition, while conformational selection is confined to a handful of cases [1]. This conclusion is based on the fact that, under the rapid equilibrium approximation, the decrease of the rate of approach to equilibrium (kobs) seen at incremental ligand concentration is diagnostic of an induced fit mechanism. In this work we analyze the kinetics of binding of Pi and BeFx (as a Pi-like ligand) to Na,K‑ATPase, and evaluate the possible models to explain the results. We observed that, although kobs decreases with [Pi] and increases with [BeFx], both processes may be explained by a conformational selection mechanism if no rapid equilibrium assumptions are invoked [2]. In this way, we show that the different behavior of kobs is not necessarily the result of a different binding-induced conformational change mechanism, and that it can be readily explained by the much higher affinity of Na,K‑ATPase for BeFx.

References
1. Tummino, P. J.; Copeland, R. A., Biochemistry 2008, 47 (20), 5481-92.
2. Vogt, A. D.; Di Cera, E., Biochemistry 2012, 51 (30), 5894-5902.

This project is supported with grants from CONICET, UBA and ANPCyT
Determination of three-dimensional structure of protein Two hybrid associated protein 1 with RanBPM (Twa1) in solution by NMR
Creators: name: Talita Stelling De Araujo
name: Cirauqui, Nuria
name: Marcius S. Almeida
Publisher: name: F1000Research
Year: 2017

description: The present work aims to determine the three-dimensional structure of the Twa1 protein, a protein highly conserved in eukaryotes, which exhibits a central role in the formation of protein complexes involved in several cellular functions such as DNA replication and ubiquitination. The primary sequence of Twa1 reveals that this protein possesses three predicted domains: the LisH domain, the CTLH domain and CRA domain, in which the last two remain with the structure unknown. The LisH domain is frequently observed in proteins involved in chromosome segregation and cell migration besides being responsible for the formation of homodimers. In order to achieve the goal of this work we produced six different constructs of the protein Twa1 in Escherichia coli: Twa1WT, Twa1-212 (lacking 16 C-terminal residues that are sensitive to proteinase K), Twa167-225 (comprises the CTLH and CRA domains), Twa11-60 (comprises the LisH domain), Twa110-120 (comprises LisH e CTLH domains) and Twa1120-212 (comprises the CTLH e CRA domains). Using several techniques such as gel Filtration assays, Circular Dichroism, Intrinsic Tryptophan Fluorescence, Proteinase K and Nuclear Magnetic Ressonance we were able to characterize the CTLH and CRA domains. The former domains are presented in a variety of proteins including some components of the CTLH complex. Our results show that the recombinant proteins are well folded with a secondary structure content of α helix. In addition, we determined the three-dimensional solution structure of the LisH domain (Twa11-60) by NMR. This structure consists of a bundle of three α-helix with a N- and C-terminal with high conformational variability.
Scoprirsi competenti. Insegnamento per lo sviluppo di competenze come leva strategica per l?innovazione in campo educativo formale
Creators: name: VOLONTA', LORENA
Publisher: name: Universit� degli studi di Bergamo
Year: 2019

description: Partendo dall?osservazione della realt� odierna si sono considerati aspetti di difficolt� in cui la scuola si trova: la scarsa motivazione degli studenti, la distanza percepita dai ragazzi tra lo studio scolastico e la vita reale e da parte dell?istituzione la frammentazione della proposta didattica e culturale e la fatica ad ammettere e ad affrontare problematiche quali i Disturbi specifici di apprendimento e in generale i Bisogni Educativi speciali in un?ottica inclusiva. Il mondo del lavoro denuncia anche l?incapacit� della scuola di formare persone in un?ottica capace di integrare sviluppo cognitivo, relazionale e pragmatico, promuovendo in realt� solo il primo aspetto. L?Europa insiste nelle sue linee guida per la formazione sullo sviluppo di competenze globali, prospettiva recepita in teoria anche nella normativa scolastica vigente in Italia, ma di fatto frenata da una pratica che non favorisce una reale autonomia. Questo lavoro intende analizzare delle possibili direzioni per affrontare le difficolt� sopra descritte, scegliendo alcuni riferimenti pedagogici ed esperienze di successo nell?innovazione didattica in Italia e in due paesi esteri. L?approfondimento realizzato fa emergere che l?obiettivo adeguato della proposta formativa deve essere il favorire lo sviluppo di competenze; la strada � quella della personalizzazione del percorso di apprendimento per intercettare bisogni e capacit� degli studenti e orientarli. Per questo diventa anche necessario fare rete con agenzie formali, informali e non formali del territorio, perch� la scuola viva della ricchezza del rapporto con la realt� che la circonda; porre al centro della proposta formativa lo studente utilizzando un?organizzazione scolastica flessibile, una molteplicit� di metodologie e strumenti al fine di mobilitare talenti e capacit� personali.
Supplemental Material, sj-pdf-1-ajh-10.1177_10499091211005735 - An Instrument to Assess Self-Perceived Competencies in End-of-Life Care for Health Care Professionals: The End-of-Life Care Questionnaire
Creators: name: Montagnini, Marcos
name: Smith, Heather M.
name: Price, Deborah M.
name: Strodtman, Linda
name: Ghosh, Bidisha
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111702 Aged Health Care

description: Supplemental Material, sj-pdf-1-ajh-10.1177_10499091211005735 for An Instrument to Assess Self-Perceived Competencies in End-of-Life Care for Health Care Professionals: The End-of-Life Care Questionnaire by Marcos Montagnini, Heather M. Smith, Deborah M. Price, Linda Strodtman and Bidisha Ghosh in American Journal of Hospice and Palliative Medicine®
Quantitative estimation of kinetic rates of ligand binding to heme proteins from molecular dynamics simulations
Creators: name: Bringas, Mauro
name: Bidon-Chanal, Axel
name: Estrin, Dario
name: Luque, Francisco Javier
name: Capece, Luciana
Publisher: name: F1000Research
Year: 2017

description: Free energy estimations have been used as tools to obtain kinetic information from different processes, using Eyring´s equation. Those calculations may have convergence issues and are strongly dependent on the reaction coordinate choice. Ligand migration through channels in proteins can be interpreted as a sequence of «jumps» of the ligand between discrete sites, which form a global “memoryless” process. The numerical simulation of each site population and the fitting of the site of interest allows us to estimate a global rate, that can directly compared to experimental data.

Based on previous studies by Blumberger et al (PCCP, vol. 13, p. 7708, 2011), we intend to study O2 and NO migration in truncated hemoglobin-N (trHbN) of mycobacterium tuberculosis (a NO-detoxifying enzyme that converts NO to nitrate). First, O2 must reach the sixth coordination position of the Fe(II)-heme complex so that the NO can be finally oxidized. In this protein, two channels to reach the active site have been described: the long channel and the short one. It is our aim to estimate uptake and release rate constants of O2 and NO and determine if the conformation of side chains located inside the channels influence the global rate constant for those processes. It is of particular interest to analyze the effect of PheE15, which is proposed to act as a «gate» controlling ligand migration through the long channel. We will present results for oxy-trHbN NO uptake, which show good agreement with experimental data, and will discuss perspectives regarding this kind of methodologies.
Additional file 1 of Relationship of thymic area with clinical-epidemiological variables and values of T-lymphocyte subpopulations in peripheral blood of children with recurrent infections
Creators: name: Sotomayor Lugo, Francisco
name: Zúñiga Rosales, Yaíma
name: Pérez Martín, Oliver
name: Hernández Reyes, Evelyn
name: Antiguas Valdés, Evelyn M.
name: Fundora Hernández, Hermes
name: Rodríguez Guitiérrez, Katia
name: Matas González, Yaima
name: Hernández, Imilla Casado
name: Villegas Valverde, Carlos Agustín
name: Torres Rives, Bárbara
name: Tam Rey, Lázara Minerva
name: González Díaz, Ihosvany
name: Hernández Rego, Yaquima
name: Pita, Ana María Simón
name: Macías Abraham, Consuelo
name: Marcheco Teruel, Beatriz
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Supplementary Table S1. Frequencies and odds ratio of thymic development according to its area and in relation to the type of delivery, in children with recurrent infections. Supplementary Table S2. Logistic multivariate regression analysis in patients with moderate-severe thymic hypoplasia. Supplementary Table S3. Correlations of absolute and relative values of T cell subpopulations with age in months. Supplementary Table S4. Correlations of absolute and relative values of T cell subpopulations with thymic area in boys and girls with recurrent infections.
ClinGen’s gene and variant curation interface suite: centralized and consistent evaluation of the clinical relevance of genes and variants
Creators: name: Wright, Matt W.
name: Dwight, Selina S.
name: Dalton, Karen
name: Minyoung Choi
name: Zhen, Jimmy
name: J. Michael Cherry
Publisher: name: F1000Research
Year: 2017

description: Critical to the field of clinical genomics is an understanding of the strength of correlation between genotype and phenotype. The central mission of ClinGen (The Clinical Genome Resource, clinicalgenome.org) is to define the “clinical relevance of genes and variants for use in precision medicine and research.” Inherent to this mission is the ability to access and evaluate evidence for a gene’s and/or variant’s role in disease in a consistent and efficient manner. Towards this goal, ClinGen has built interconnected curation interfaces, one for gene curation and one for variant curation. The rich evidence captured by both interfaces is available in a structured format that allows it to be easily accessed via ClinGen’s public portal (clinicalgenome.org).

The ClinGen gene and variant curation interfaces have been developed according to the following important specifications: 1) variant curation follows the ACMG-AMP Standards and Guidelines (Richards et al 2015, PMID:25741868), while gene curation follows the Clinical Validity Classifications framework established by ClinGen’s Gene Curation Work Group, 2) both interfaces centralize evidence from relevant resources in order to enable efficient and consistent curation, 3) curated literature evidence and evidence retrieved from external resources are shared between the gene and variant curation tools, 4) the interfaces are designed to guide biocurators through the curation process, 5) controlled vocabularies and ontologies are an important part of the design in order to promote the capture of discrete evidence, facilitate connections, and promote consistency, 6) external and curated evidence is viewable by all biocurators, while curated evidence can only be edited by its creator, 7) the interfaces support expert review of provisional classifications and interpretations by allowing access to all evidence, 8) contextual help and documentation are included to assist the biocurator, and 9) data is stored in standard JSON-LD format to define rich relationships and facilitate data exchange.

Both tools are now in production (curation.clinicalgenome.org) and currently accessible to ClinGen biocurators and approved groups from the broader community.  A demo version of the interfaces (curation-test.clinicalgenome.org), which does not permanently save data, is available via both registered and generic (non-registered) access to allow exploration. We expect active use of the ClinGen curation interfaces will facilitate the implementation of the ACMG variant classification guidelines across diverse disease genes.
Cómo crear ediciones digitales académicas entre La Habana y Berlín. El caso de Proyecto Humboldt Digital (ProHD)
Creators: name: Rojas Castro, Antonio
name: Terrón, Grisel
name: Terrón, Grisel
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Cuba
subject: Humboldt, Alexander von, 1769-1859
subject: Latin America

description: Studies on the Prussian writer and naturalist Alexander von Humboldt and editions of his work are abundant. Among the many outstanding chapters of his famous journey through the American tropics, the two visits to Cuba (1800–1801/1804) stand out as a particular case. To this day very few original documents are known about his actual visits, the colonial sources that informed him and the history of his reception. This is due, in large part, to the fact that documentary sources are difficult to access. To overcome this difficulty, the Project Humboldt Digital was born in 2019, a cooperation project carried out between Havana and Berlin, whose main objective is to publish a collection of texts related to Humboldt’s stay in Cuba. In this article we aim to explain how our digital scholarly editions have been created from a methodological point of view. After outlining the origins, we present the workflow developed between the Oficina del Historiador de la Ciudad de La Habana and the Berlin-Brandenburg Academy of Sciences and Humanities to digitize, describe, publish, edit and preserve in digital format a collection of previously selected texts. Also, we describe the model of data representation in TEI format, as well as the tools employed to encode and publish the editions. Finally, we analyze the first editorial results obtained and offer some conclusions on the main challenges faced.
sj-pdf-3-jhs-10.1177_17531934211004080 - Supplemental material for The three-dimensional shape symmetry of the lunate and its implications
Creators: name: Nazlı Tümer
name: Hiemstra, Olivier
name: Schreurs, Yvonne
name: Kraan, Gerald A.
name: Van Der Stok, Johan
name: Zadpoor, Amir A.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-3-jhs-10.1177_17531934211004080 for The three-dimensional shape symmetry of the lunate and its implications by Nazlı Tümer, Olivier Hiemstra, Yvonne Schreurs, Gerald A. Kraan, Johan van der Stok and Amir A. Zadpoor in Journal of Hand Surgery (European Volume)
Ediciones digitales académicas: concepto, estándares de calidad y software de publicación
Creators: name: Alvite Díez, María Luisa
name: Rojas Castro, Antonio
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Software engineering
subject: Computer software--Development--Evaluation

description: Se revisa y discute el concepto de edición digital académica (EDA), así como las diversas denominaciones empleadas para hacer referencia a la misma. El estudio indaga en el alcance de los estándares de calidad planteados para este tipo de edición y explora los softwares para la publicación. Se completa el trabajo con un análisis evaluativo de una muestra de aplicaciones, profundizando en sus características, en los condicionantes sobre las interfaces de usuario a las que dan acceso y en su adecuación a los estándares. Las conclusiones insisten en la urgencia de evaluar de forma crítica y sistemática el software de edición. Se destaca positivamente el desarrollo paulatino de software abierto e interoperable, asentado en la codificación de los textos siguiendo la Text encoding initiative (TEI), que optimizan la reutilización y preservación de los datos. Sin embargo, la perdurabilidad de las interfaces web y la sostenibilidad de estos proyectos digitales requieren infraestructuras de investigación adecuadas, para lo que se propone promover sinergias con bibliotecas y editoriales tradicionales, entre otros mediadores. Por último, para avanzar en la adecuación de los modelos de edición al paradigma digital, se subraya la necesidad de consensuar patrones de visualización de EDAs, por parte de la comunidad académica, así como de emprender estudios de usuarios que garanticen la adaptación de las EDAs al público objetivo al que se dirigen.
Second Xeric'S E-Newsletter - May 2016
Creators: name: SOULA Guylène
Publisher: name: Zenodo
Year: 2016
Subjects: electric vehicle (EV)
Climate Control System (CCS)
energy efficiency
dehumidification
hydrophobic membrane

description: This delivrable written in the frame of the XERIC project (WP5 - Impact and Exploitation) explains how the second e-newsletter was created and sent and what makes up the mailing lists. The content of the newsletter is then displayed, along with the coordinator’s full editorial. The e-newsletters were released twice a year to XERIC’s mailing list, to share news about the project and its activities (6 e-newsletters sent over the duration of XERIC, available on XERIC website and archived in ZENODO).
sj-pdf-1-cre-10.1177_02692155211006860 – Supplemental material for Clinical effectiveness of shockwave therapy in lateral elbow tendinopathy: systematic review and meta-analysis
Creators: name: Karanasios, Stefanos
name: Tsamasiotis, Georgios K.
name: Michopoulos, Konstantinos
name: Sakellari, Vasiliki
name: Gioftsos, George
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-cre-10.1177_02692155211006860 for Clinical effectiveness of shockwave therapy in lateral elbow tendinopathy: systematic review and meta-analysis by Stefanos Karanasios, Georgios K. Tsamasiotis, Konstantinos Michopoulos, Vasiliki Sakellari and George Gioftsos in Clinical Rehabilitation
Additional file 1 of Obesity Treatments to Improve Type 1 Diabetes (OTID): a randomized controlled trial of the combination of glucagon-like peptide 1 analogues and sodium-glucose cotransporter 2 inhibitors—protocol for Obesity Treatments to Improve Type 1 Diabetes (the OTID trial)
Creators: name: Al-Ozairi, Ebaa
name: Narula, Kavita
name: Miras, Alexander D.
name: Taghadom, Etab
name: Samad, Abeer El
name: Al Kandari, Jumana
name: Alyosef, Anas
name: Mashankar, Anant
name: Al-Najim, Werd
name: le Roux, Carel W.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Virology

description: Additional file 1.
Third Xeric'S E-Newsletter - December 2016
Creators: name: SOULA Guylène
Publisher: name: Zenodo
Year: 2016
Subjects: electric vehicle (EV)
Climate Control System (CCS)
energy efficiency
dehumidification
hydrophobic membrane

description: This delivrable written in the frame of the XERIC project (WP5 - Impact and Exploitation) explains how the third e-newsletter was created and sent and what makes up the mailing lists. The content of the newsletter is then displayed, along with the coordinator’s full editorial. The e-newsletters were released twice a year to XERIC’s mailing list, to share news about the project and its activities (6 e-newsletters sent over the duration of XERIC, available on XERIC website and archived in ZENODO).
sj-docx-2-nnr-10.1177_15459683211005022 – Supplemental material for Translational Value of Skilled Reaching Assessment in Clinical and Preclinical Studies on Motor Recovery After Stroke
Creators: name: Van Lieshout, Eline C. C.
name: Boonzaier, Julia
name: Pel, Adam J.
name: Van Heijningen, Caroline L.
name: Vink, Jord J.
name: Visser-Meily, Johanna M. A.
name: Van Tilborg, Geralda A. F.
name: Dijkhuizen, Rick M.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: Neuroscience

description: Supplemental material, sj-docx-2-nnr-10.1177_15459683211005022 for Translational Value of Skilled Reaching Assessment in Clinical and Preclinical Studies on Motor Recovery After Stroke by Eline C. C. van Lieshout, Julia Boonzaier, Adam J. Pel, Caroline L. van Heijningen, Jord J. Vink, Johanna M. A. Visser-Meily, Geralda A. F. van Tilborg and Rick M. Dijkhuizen in Neurorehabilitation and Neural Repair
Additional file 1 of Epigenome-wide association study of dietary fatty acid intake
Creators: name: Lange de Luna, Julia
name: Nounu, Aayah
name: Neumeyer, Sonja
name: Sinke, Lucy
name: Wilson, Rory
name: Hellbach, Fabian
name: Matías-García, Pamela R.
name: Delerue, Thomas
name: Winkelmann, Juliane
name: Peters, Annette
name: Thorand, Barbara
name: Beekman, Marian
name: Heijmans, Bastiaan T.
name: Slagboom, Eline
name: Gieger, Christian
name: Linseisen, Jakob
name: Waldenberger, Melanie
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. Supplementary information.
Fourth Xeric'S E-Newsletter - May 2017
Creators: name: BOUCHER, Mathilde
Publisher: name: Zenodo
Year: 2017
Subjects: electric vehicle (EV)
Climate Control System (CCS)
energy efficiency
dehumidification
hydrophobic membrane

description: This delivrable written in the frame of the XERIC project (WP5 - Impact and Exploitation) explains how the fourth e-newsletter was created and sent and what makes up the mailing lists. The content of the newsletter is then displayed, along with the coordinator’s full editorial. The e-newsletters were released twice a year to XERIC’s mailing list, to share news about the project and its activities (6 e-newsletters sent over the duration of XERIC, available on XERIC website and archived in ZENODO).
sj-pdf-1-jcb-10.1177_0271678X211006291 - Supplemental material for Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment
Creators: name: Zeng, Min
name: Wei, Tao-Feng
name: Chen, Cong
name: Shen, Chen
name: Gao, Tong-Yao
name: Xie, Xian
name: Wu, Ming
name: Lu, Yun-Bi
name: Zhang, Wei-Ping
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Emergency Medicine
subject: Endocrinology
subject: Medicine
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Radiology and Organ Imaging
subject: Cell Biology
subject: Biochemistry
subject: Biological Sciences not elsewhere classified
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jcb-10.1177_0271678X211006291 for Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment by Min Zeng, Tao-Feng Wei, Cong Chen, Chen Shen, Tong-Yao Gao, Xian Xie, Ming Wu, Yun-Bi Lu and Wei-Ping Zhang in Journal of Cerebral Blood Flow & Metabolism
sj-pdf-1-pun-10.1177_14624745211006039 - Supplemental material for The downside of downsizing: Persistence of racial disparities following state prison reform
Creators: name: Lerman, Amy E
name: Mooney, Alyssa C
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-pun-10.1177_14624745211006039 for The downside of downsizing: Persistence of racial disparities following state prison reform by Amy E Lerman and Alyssa C Mooney in Punishment & Society
¿Sin equivalencia? Una reflexión sobre la traducción al español de recursos educativos abiertos
Creators: name: Rojas Castro, Antonio
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Translation studies
subject: Digital humanities

description: Los esfuerzos de traducción dentro de las humanidades digitales han tomado muchas formas,desde iniciativas informales ad hoc y DH Whisperers para conferencias a interfaces multilingües o traducciones de libros y artículos. Ahora bien, la traducción de material pedagógico (en concreto, tutoriales) sigue siendo un desafío, ya que no solo necesitan traducirse lingüísticamente, sino también adaptarse en contenido, a veces código y contexto. Basándonos en algunas nociones de la teoría de la traducción y en nuestra experiencia, en este artículo consideramos la forma de traducción finalista (Nord 2018) para metodologías digitales con el objetivo de generar un discurso crítico sobre los desafíos de traducir del inglés al español las lecciones de Programming Historian. Nuestra contribución defiende la necesidad de reflexionar sobre las epistemologías resultantes de las prácticas digitales y de reconocer cómo este desequilibrio condiciona el aprendizaje de habilidades digitales. Nuestro objetivo final es desarrollar una estrategia creativa que apoye el multiculturalismo y la diversidad en el campo de las humanidades digitales.
Additional file 1 of Flexible emotional regulation typology: associations with PTSD symptomology and trait resilience
Creators: name: Spikol, Eric
name: McGlinchey, Emily
name: Robinson, Martin
name: Armour, Cherie
Publisher: name: figshare
Year: 2024
Subjects: Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Supplementary Material 1
Optimization Of Electromechanical Properties Of Piezoelectric Nanocomposite Elastomers
Creators: name: Bird, Evan
name: Wood, David
Publisher: name: Zenodo
Year: 2017

description: Nanocomposite elastomers, including highly flexible strain gauges and foam, have been shown to exhibit a piezo-response, or change in electrical impedance, under mechanical strain. Both classes of sensors are comprised of an elastomer matrix (typically silicone for strain gauges and polyurethane or latex for foam) mixed with conductive nanofillers including nickel-coated carbon fiber and nickel powder. Though these sensors are used for different applications, their piezoresistive responses can be optimized with respect to the same variables. An optimal piezoresponse for each sensor is defined by a maximum range of output resistance registered during strain. Parameters of both nanocomposites that similarly affect their piezo-responses include sensor size (length, width, height) and volume fraction of the conductive filler. Since the relationships between these and the resistance values of interest are similar between both sensors, they are selected to optimize as design variables. The optimal width, thickness, and filler volume fraction for a piezoresistive nanocomposite is found deterministically and accounting for uncertainty. Results show that small sensors with a high volume fraction of conductive fillers yield optimal resistance ranges at a given strain.
sj-pdf-1-ems-10.1177_14690667211005055 - Supplemental material for Atmospheric pressure chemical ionisation mass spectrometry for the routine analysis of low molecular weight analytes
Creators: name: Gates, Paul J
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-pdf-1-ems-10.1177_14690667211005055 for Atmospheric pressure chemical ionisation mass spectrometry for the routine analysis of low molecular weight analytes by Paul J Gates in European Journal of Mass Spectrometry
La publicación de ediciones digitales académicas y el caso de las Soledades de Luis de Góngora
Creators: name: Rojas Castro, Antonio
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Spanish literature

description: Este artículo tiene por objetivo caracterizar el proceso de publicación de ediciones digitales académicas mediante herramientas informáticas que transforman documentos XML/TEI a HTML. Tras explicar las diferencias existentes entre las webs dinámicas y las webs estáticas en el primer apartado, se exponen algunos desafíos que supone el uso de herramientas de publicación y los efectos derivados de la estandarización y se analiza la publicación web de las Soledades de Luis de Góngora realizada con la herramienta Edition Visualization Technology. Palabras clave: This article aims to describe the process of publishing of digital scholarly editions using tools that transform XML/TEI documents into HTML. After introducing the main differences between dynamic and static webs in the first section, this article discusses some challenges involved in the use of publishing tools and the effects derived from standardization, and analyzes the web publication of Luis de Góngora's Soledades built with Edition Visualization Technology.
Acute paraparesis in adult male
Creators: name: Lopes Das Neves, Pedro Miguel
Publisher: name: EURORAD
Year: 2018
Subjects: subject: Neuroradiology spine
subject: MR
subject: MR-Diffusion/Perfusion
subject: Imaging sequences
subject: Haemorrhage

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 74 years
description: Clinical History: Patient presented with intense back pain aggravating in the past 3 days and compromising gait. After performing CT imaging, and considering the recent medical history of infectious spondylodiscitis, a recurrence of the infectious process was assumed and a... Final Diagnosis: Spontaneous spinal epidural hematoma
sj-docx-1-qjp-10.1177_17470218211009227 – Supplemental material for Embodied mental imagery improves memory
Creators: name: Marre, Quentin
name: Huet, Nathalie
name: Labeye, Elodie
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-qjp-10.1177_17470218211009227 for Embodied mental imagery improves memory by Quentin Marre, Nathalie Huet and Elodie Labeye in Quarterly Journal of Experimental Psychology
sj-docx-3-qjp-10.1177_17470218211009227 – Supplemental material for Embodied mental imagery improves memory
Creators: name: Marre, Quentin
name: Huet, Nathalie
name: Labeye, Elodie
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-3-qjp-10.1177_17470218211009227 for Embodied mental imagery improves memory by Quentin Marre, Nathalie Huet and Elodie Labeye in Quarterly Journal of Experimental Psychology