cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MONTE CARLO SIMULATION AND PORTFOLIO OPTIMISATION, A CASE STUDY
Creators: name: Maldonado, Victor Goncalves
Publisher: name: Zenodo
Year: 2022
Subjects: Monte Carlo Simulation, Portfolio Optimisation, Modern Portfolio Theory, Capital Asset Pricing Model, Investment, Economics, Finance

description: Abstract The Monte Carlo Simulation consists of simulating a stochastic model several times, to estimate the probability distribution of the stochastic model. It yields information such as volatility and average return, that can be used to forecast financial events’ probabilities. The Monte Carlo Simulation is extensively used in economics and finance, but few papers in the literature review access its effectivity properly. Moreover, most papers apply the method without considering proper economics and finance theories such as the Capital Asset Pricing Model and the Modern Portfolio Theory. Therefore, this paper accessed the literature related, and tried to fill its gaps. Finally, a portfolio was build considering appropriated theories, and its allocation optimised by the Monte Carlo Simulation. The optimised portfolio’s performance was compared to a random allocated portfolio. The optimised portfolio attended the theoretical demands established when the portfolio was built, while the random portfolio, even more profitable, performed the opposite of what was expected from the portfolio’s characteristics.
sj-pdf-1-ije-10.1177_0020720920965872 - Supplemental material for UPCT-Bloopbusters: A methodology of teaching physics and technology concepts using movie scenes and related experiments
Creators: name: José-Víctor Rodríguez
name: Juan-Francisco Sánchez-Pérez
name: Castro-Rodríguez, Enrique
name: José-Luis Serrano-Martínez
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, sj-pdf-1-ije-10.1177_0020720920965872 for UPCT-Bloopbusters: A methodology of teaching physics and technology concepts using movie scenes and related experiments by José-Víctor Rodríguez, Juan-Francisco Sánchez-Pérez, Enrique Castro-Rodríguez and José-Luis Serrano-Martínez in International Journal of Electrical Engineering & Education
title: Stabilized HME composition with small drug particles
Creators: name: Williams, Robert O.
name: McGinity, James W.
name: Miller, Dave A.
name: McConville, Jason T.
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: A61K9/146
subject: A61K9/1635
subject: A61K9/1641
subject: A61K9/5138
subject: A61K31/496
subject: A61K31/55
subject: A61K31/58
subject: A61K38/13
subject: No longer published

description: A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does not dissolve the drug-containing particles during extrusion. As a result, a majority or at least 90% wt. of the drug-containing particles in the extrudate are deaggregated during extrusion into essentially primary crystalline and/or amorphous particles. PEO is a suitable carrier material for drugs insoluble in the solid state in this carrier. Various functional excipients can be included in the carrier system to stabilize the particle size and physical state of the drug substance in either a crystalline and/or amorphous state. The carrier system is comprised of at least one thermal binder, and may also contain various functional excipients, such as: super-disintegrants, antioxidants, surfactants, wetting agents, stabilizing agents, retardants, or similar functional excipients. A hydrophilic polymer, such as hydroxypropyl methylcellulose (HPMC E15), polyvinyl alcohol (PVA), or poloxamer, and/or a surfactant, such as sodium lauryl sulfate (SLS), can be included in the composition. A process for preparing the extrudate is conducted at a temperature approximating or above the softening or melting temperature of the matrix and below the point of solubilization of drug-containing particles in the carrier system, and below the recrystallization point in the case of amorphous fine drug particles.
Senftleben_2020_Supplement_2 – Supplemental material for To stay or not to stay: The stability of choice perseveration in value-based decision making
Creators: name: Senftleben, Ulrike
name: Schoemann, Martin
name: Rudolf, Matthias
name: Scherbaum, Stefan
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Senftleben_2020_Supplement_2 for To stay or not to stay: The stability of choice perseveration in value-based decision making by Ulrike Senftleben, Martin Schoemann, Matthias Rudolf and Stefan Scherbaum in Quarterly Journal of Experimental Psychology
title: Method for the detection and quantification of analytes using three-dimensional paper-based devices
Creators: name: Liu, Hong
name: Crooks, Richard M.
name: Scida, Karen
name: Renault, Christophe
Publisher: name: United States Patent and Trademark Office
Year: 2017
Subjects: subject: B01L3/5023
subject: B01L3/50270
subject: B01L3/50271
subject: B01L3/50273
subject: B01L3/5055
subject: B01L2200/12
subject: B01L2300/045
subject: B01L2300/0627
subject: B01L2300/0645
subject: B01L2300/0816
subject: B01L2300/0877
subject: B01L2300/126
subject: B01L2400/0406
subject: B01L2400/065
subject: C12Q1/001
subject: C12Q1/6813
subject: C12Q2565/625
subject: G01N27/3276
subject: G01N33/54373
subject: G01N33/5438
subject: G01N33/48707
subject: G01N2035/00158
subject: Y10T29/49984
subject: No longer published

description: Described herein are three-dimensional (3-D) paper fluidic devices. The entire 3-D device is fabricated on a support layer formed from a single sheet of material and assembled by folding the support layer. The folded structure may be enclosed in an impermeable cover or package. Chemically sensitive particles may be disposed in the support layer for use in detecting analytes.
title: Fracturing fluid for prevention of shale fracture hydration during well stimulation by hydraulic fracturing
Creators: name: Van Oort, Eric
name: Downs, John David
Publisher: name: United States Patent and Trademark Office
Year: 2018
Subjects: subject: C09K8/68
subject: C09K8/885
subject: C09K2208/28

description: Friction reducers for hydraulic fracturing fluids, hydraulic fracturing fluids containing the friction reducers, and methods of making and using same are disclosed. The friction reducers comprise ethylene oxide polymers, propylene oxide polymers, ethylene oxide-propylene oxide co-polymers, and combinations thereof, and can further comprise a dispersant, such as polypropylene glycol. The friction reducer formulations can be active across a wide range of brine salinities, and tolerant of high levels of divalent cations in solution. The friction reducers can have a cloud point temperature, above which temperature they can precipitate out of solution and deposit on a surface of a hydrocarbon-bearing formation to inhibit hydration of the shale formations lining the fractures.
title: Redox flow battery that uses complexes of cobalt and iron with amino-alcohol ligands in alkaline electrolytes to store electrical energy
Creators: name: Bard, Allen J.
name: Arroyo, Netzahualcoyotl
Publisher: name: United States Patent and Trademark Office
Year: 2018
Subjects: subject: H01M8/188
subject: H01M4/38
subject: H01M4/60
subject: H01M8/083
subject: H01M8/20
subject: H01M6/16
subject: H01M8/08
subject: H02J7/00
subject: H02J7/0068
subject: Y02E60/528

description: A redox flow battery that uses metal complexes with amino-alcohol ligands as the electroactive species in alkaline electrolytes to store electrical energy. The battery includes a first and a second electrolyte storage unit that each includes a metal complex selected from transition metals with an amino-alcohol ligand as an electroactive species in an alkaline electrolyte. Such solutions in these electrolyte storage units are each prepared by mixing stoichiometric amounts of a metal ion and an amino-alcohol ligand in water to form a metal-ligand mixture followed by adding an amount corresponding to 3-5 moles/liter of an alkaline electrolyte solution to each metal-ligand mixture to form a metal complex with the amino-alcohol ligand in the alkaline electrolyte to be used by a storage unit. As a result, the operational and maintenance costs of the redox flow battery are reduced while reducing the complexity of the manufacturing process.
title: Bi-layer pseudo-spin field-effect transistor
Creators: name: Banerjee, Sanjay K.
name: Tutuc, Emanuel
name: Register, Leonard Franklin
name: MacDonald, Allan
name: Palle, Dharmendar Reddy
Publisher: name: United States Patent and Trademark Office
Year: 2012
Subjects: subject: B82Y10/00
subject: H01L29/775
subject: H01L29/1606
subject: H01L29/7781
subject: H01L29/7831
subject: 257/39
subject: 257/36
subject: 438/158

description: A bi-layer pseudo-spin field-effect transistor (BiSFET) is disclosed. The BiSFET includes a first and second conduction layers separated by a tunnel dielectric. The BiSFET transistor also includes a first gate separated from the first conduction layer by an insulating dielectric layer, and a second gate separated from the second conduction layer by an insulating layer. These conduction layers may be composed of graphene. The voltages applied to the first and/or second gates can control the peak current and associated voltage value for current flow between top and bottom conduction channels, and interlayer current voltage characteristic exhibiting negative differential resistance. BiSFETs may be used to make a variety of logic gates. A clocked power supply scheme may be used to facilitate BiSFET-based logic.
title: High strength induction machine, rotor, rotor cage end ring and bar joint, rotor end ring, and related methods
Creators: name: Caprio, Matthew T.
name: Lelos, Vasileios
name: Herbst, John
name: Manifold, Stephen
name: Jordon, Howard
Publisher: name: United States Patent and Trademark Office
Year: 2009
Subjects: subject: H02K17/165
subject: 310/211

description: A high strength induction machine, rotor, rotor cage end ring and bar joint, rotor end ring, and related methods are provided. An embodiment of an end ring and bar joint includes a main body adapted to substantially surround a rotor shaft when mounted thereto, a plurality of slots extending inwardly in a radial direction from outer peripheries of the main body, a thicker end ring section extending outwardly from a medial portion of the main body, being thicker than the outer peripheries of the main body, and also being adapted to substantially surround the rotor shaft, and a plurality of bosses extending axially and outwardly from outer peripheral portions in a direction opposite to the thicker end ring section and each adapted to receive an end portion of a rotor bar therein.
title: Method of using a four terminal hybrid silicon/organic field effect sensor device
Creators: name: Dodabalapur, Ananth
name: Sharma, Deepak Kumar
name: Fine, Daniel
Publisher: name: United States Patent and Trademark Office
Year: 2009
Subjects: subject: B82Y10/00
subject: B82Y15/00
subject: B82Y30/00
subject: G01N27/4141
subject: H01L27/286
subject: H01L2924/0002
subject: H01L2924/00
subject: 257/40
subject: 324/71.5
subject: 324/762.9

description: A four terminal field effect device comprises a silicon field effect device with a silicon N-type semiconductor channel and an N+ source and drain region. An insulator is deposited over the N-type semiconductor channel. An organic semiconductor material is deposited over the insulator gate forming a organic semiconductor channel and is exposed to the ambient environment. Drain and source electrodes are deposited and electrically couple to respective ends of the organic semiconductor channel. The two independent source electrodes and the two independent drain electrodes form the four terminals of the new field effect device. The organic semiconductor channel may be charged and discharged electrically and have its charge modified in response to chemicals in the ambient environment. The conductivity of silicon semiconductor channel is modulated by induced charges in the common gate in response to charges in the organic semiconductor channel.
title: Switched-capacitor circuit
Creators: name: Yan, Shouli
name: Cao, Zhiheng
Publisher: name: United States Patent and Trademark Office
Year: 2009
Subjects: subject: H03F3/005
subject: 327/337
subject: 327/96

description: A low-power switched-capacitor circuit is disclosed. The low-power switched-capacitor circuit includes a p-channel switched-capacitor integrator and an n-channel switched-capacitor integrator. The p-channel switched-capacitor integrator includes a first set of input transistors controlled by a first set of capacitors and switches. The n-channel switched-capacitor integrator includes a second set of input transistors controlled by a second set of capacitors and switches. The p-channel switched-capacitor integrator and the n-channel switched-capacitor integrator function together in a push-pull fashion such that a required transconductance as well as width and drain current of the first and second sets of input transistors are reduced by half of those in a conventional switch-capacitor circuit.
SYNTHESIS AND CRYSTAL STRUCTURE OF (E)-3-(4-BUTOXYPHENYL)-1-(NAPHTHALEN-1-YL)PROP-2-EN-1-ONE
Creators: name: Kumar, Sanjay
name: Jayashree, A.
name: Narayana, B.
name: Sarojini, B. K.
name: Kótai, László
name: Anthal, Sumati
name: Kant, Rajni
Publisher: name: European Chemical Bulletin
Year: 2017

description: Chalcone derivative (E)-3-(4-Butoxyphenyl)-1-(naphthalen-1-yl)prop-2-en-1-one (C23 H22 O2) crystallizes in monoclinic system with space group 'P 21/c ' and unit cell parameters: a = 15.1595(14) Å, b = 7.6644(7) Å, c = 15.8634(15) Å,   b = 96.942(7)o. The crystal structure was solved using direct methods and refined by full matrix least squares procédures to a final R-factor of 0.0911 for 1591 observed reflections. The enone moiety adopts E conformation with respect to C12=C13 bond.The molecules in the unit cell are linked by weak C–H⋅⋅⋅O and π-π interactions. The molecule contains two C–H⋅⋅⋅O intramolecular interactions which stabilizes the crystal structure
description: European Chemical Bulletin, Vol 5, No 12 (2016): European Chemical Bulletin
title: Development of influenza A antivirals
Creators: name: Krug, Robert M.
name: Twu, Karen Y.
Publisher: name: United States Patent and Trademark Office
Year: 2009
Subjects: subject: A61K38/16
subject: A61K38/17
subject: A61K39/0008
subject: A61K2039/55516
subject: C07K14/47
subject: C07K14/005
subject: C07K14/705
subject: C12N5/0636
subject: C12N5/163
subject: C12N7/00
subject: C12N7/04
subject: C12N2760/16111
subject: C12N2760/16134
subject: Y10S514/888
subject: 424/204.1
subject: 424/209.1
subject: 435/5
subject: 435/6.13
subject: 435/29
subject: 435/235.1
subject: 514/888

description: The present invention includes compositions, methods and systems to isolate and characterize novel antiviral agents by contacting the antiviral agent with the F2F3 zinc fingers of a CPSF30 protein and an Influenza A NS1A protein; and determining whether the binding between the CPSF30 protein and the Influenza A NS1A protein is reduced.
REMOVAL OF POLYPHOSPHATES FROM WASTEWATER BY MAGNETIC COMPOSITE MINERAL SORBENTS
Creators: name: Makarchuk, Oksana
name: Dontsova, Tetiana
Publisher: name: European Chemical Bulletin
Year: 2017

description: Magnetic composite mineral sorbents based on saponite, spondyle, palygorskite clays and magnetite were created. The ability of magnetic sorbents to remove tripolyphosphate and hexametaphosphate from aqueous solutions has been studied for different adsorbate concentrations by varying the amount of adsorbent, temperature and shaking time. The kinetics of adsorption process data was examined using the pseudo-first-order, pseudo-second-order kinetics and the Boyd-Adamson internal diffusion kinetic models. The adsorption kinetics was best described by the pseudo second-order model with good correlation (R2 ≈ 1.00). The experimental isotherm data were analyzed using the Langmuir, Freundlich, Temkin and Dubinin–Radushkevich equations. The experimental data well fitted to Langmuir isotherm model. It was found that calculated adsorption capacities of magnetic composites relatively tripolyphosphate (550-620 mg·g-1) and hexametaphosphate (670-730 mg·g-1) were good agreed with experimentally obtained values. The thermodynamic parameters, such as ΔG0, ΔH0 and ΔS0 were also determined and evaluated. It was indicated that the adsorption of polyphosphates was feasible, spontaneous and exothermic in nature and the physical nature of the process was confirmed. Thus, cheap magnetic sorbents based on natural clays and magnetite, which not only quickly separated from the solution by magnetic separation, but effectively removed polyphosphates were obtained.
description: European Chemical Bulletin, Vol 5, No 12 (2016): European Chemical Bulletin
Modeling trends and periodic components in geodetic time series: a unified approach
Creators: name: Kermarrec, Gaël
name: Maddanu, Federico
name: Klos, Anna
name: Proietti, Tommaso
name: Bogusz, Janusz
Publisher: name: Berlin ; Heidelberg : Springer
Year: 2024
Subjects: subject: Fractional noise
subject: Fractional sinusoidal waveform process
subject: Geodetic time series
subject: Kalman filter
subject: Long memory
subject: Random walk
subject: State space models
subject: Stochastic sinusoidal signals
subject: Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaften

description: Geodetic time series are usually modeled with a deterministic approach that includes trend, annual, and semiannual periodic components having constant amplitude and phase-lag. Although simple, this approach neglects the time-variability or stochasticity of trend and seasonal components, and can potentially lead to inadequate interpretations, such as an overestimation of global navigation satellite system (GNSS) station velocity uncertainties, up to masking important geophysical phenomena. In this contribution, we generalize previous methods for determining trends and seasonal components and address the challenge of their time-variability by proposing a novel linear additive model, according to which (i) the trend is allowed to evolve over time, (ii) the seasonality is represented by a fractional sinusoidal waveform process (fSWp), accounting for possible non-stationary cyclical long-memory, and (iii) an additional serially correlated noise captures the short term variability. The model has a state space representation, opening the way for the evaluation of the likelihood and signal extraction with the support of the Kalman filter (KF) and the associated smoothing algorithm. Suitable enhancements of the basic methodology enable handling data gaps, outliers, and offsets. We demonstrate the advantage of our method with respect to the benchmark deterministic approach using both observed and simulated time series and provide a fair comparison with the Hector software. To that end, various geodetic time series are considered which illustrate the ability to capture the time-varying stochastic seasonal signals with the fSWp.
title: Method and system for performing optical proximity correction with process variations considerations
Creators: name: Pan, Zhigang
name: Yu, Peng
Publisher: name: United States Patent and Trademark Office
Year: 2010
Subjects: subject: G03F1/36
subject: 702/85
subject: 702/107
subject: 716/53

description: A method for performing optical proximity correction with process variations considerations is disclosed. The maximum aerial gradient direction for a control point associated with an edge is initially determined. Then, a variational edge placement error E along the maximum aerial image intensity gradient direction of the control point is calculated. A determination is made whether or not |CE·n| is equal to or greater than a manufacturing grid, where n is the direction perpendicular to a segment pointing outward, and C is a constant. If |CE·n| is equal to or greater than a manufacturing grid, the edge is moved by −CE·n.
PHASE COMPOSITION, THERMAL BEHAVIOR AND MAGNETIC PROPERTIES OF ZINC- AND NICKEL-BEARING POWDERS FORMED ON THE STEEL SURFACE IN THE OPEN-AIR SYSTEM
Creators: name: Lavrynenko, O.
name: Dudchenko, N.
name: Pavlenko, O.
name: Brik, A.
Publisher: name: European Chemical Bulletin
Year: 2017

description: The nanosized powders formed on the steel surface contacting with zinc and nickel inorganic water salt solutions have been studied using an X-ray diffraction method, thermal analytical measurements (TG/DTG, DTA,) scanning electron microscopy, and magnetometry. It was shown that the formation of a single mineral phase of a non-stoichiometric spinel ferrite when zinc and nickel nitrate solutions were used as the dispersion medium, but in the presence of chloride-containing salts three mineral phases (spinel ferrite, lepidocrocite, and goethite) were determined in the phase composition of the surface powders. When sulfate solutions were chosen as the dispersion medium the mixed hydroxysulfate layered double hydroxides (LDHs) simultaneously appeared among other components of the powders. Due to cation exchange between Fe2+ and Zn2+ or Ni2+ the mixed LDH structures achieved stability against further oxidation and thermal transformation. Hence, the presence of mixed LDHs in the phase composition of the powders significantly complicates the obtaining of homogenous superparamagnetic 3d-metal doped spinel ferrite and iron oxide powders.
description: European Chemical Bulletin, Vol 5, No 12 (2016): European Chemical Bulletin
Numerical Modeling and Open-Source Implementation of Variational Partition-of-Unity Localizations of Space-Time Dual-Weighted Residual Estimators for Parabolic Problems
Creators: name: Thiele, J.P.
name: Wick, T.
Publisher: name: New York, NY [u.a.] : Springer Science + Business Media B.V.
Year: 2024
Subjects: subject: Dual weighted residuals
subject: Goal-oriented a posteriori error estimations
subject: Localisation
subject: Open source implementation
subject: Parabolic problems
subject: Dewey Decimal Classification::000 | Allgemeines, Wissenschaft::000 | Informatik, Wissen, Systeme::004 | Informatik

description: In this work, we consider space-time goal-oriented a posteriori error estimation for parabolic problems. Temporal and spatial discretizations are based on Galerkin finite elements of continuous and discontinuous type. The main objectives are the development and analysis of space-time estimators, in which the localization is based on a weak form employing a partition-of-unity. The resulting error indicators are used for temporal and spatial adaptivity. Our developments are substantiated with several numerical examples.
title: OCT using spectrally resolved bandwidth
Creators: name: Feldman, Marc D.
name: Milner, Thomas E.
name: Grant, Robert
name: Oh, Jung-Hwan
name: Kim, Jee-Hyun
name: Kumar, Karthik
name: Chen, Shaochen
name: Han, Li-Hsin
name: Kim, Eunha
name: Condit, Chris
name: Kemp, Nate
Publisher: name: United States Patent and Trademark Office
Year: 2010
Subjects: subject: A61B5/0073
subject: A61B1/00096
subject: A61B1/00167
subject: A61B1/00172
subject: A61B5/0066
subject: A61B5/0084
subject: A61B5/6852
subject: 600/407
subject: 600/160

description: An apparatus is disclosed for studying an object based on at least one of polarization, space, position or angle of light that has reflected from the object. An optical tomographic instrumentation of the apparatus includes a light source coupled to a source path, a sample path, a reference path, and a detection path, wherein the light source generates a spectrally resolved bandwidth. The spectrally resolved bandwidth includes a plurality of spectrally resolved cells and a detector in the detection path for analyzing light reflected from an object in the sample path and the light reflected in the reference path based upon at least one of the polarization, spatial relationship, position or angle domains.
Antimicrobial Resistance of Enterobactericeae from flies caught in Maputo, Mozambique.
Creators: name: Victor Ilevbare
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Resistance to antimicrobials has been reported with a notable frequency in species belonging to the family Enterobacteriaceae. The genes simply confer resistance to antibiotics, which may enable the pathogen to survive treatment, which can result in deleterious health outcomes. Hence, this project measured the phenotypic antimicrobial resistance (AMR) of Enterobacteriaceae isolated from 30 flies caught in the living environment in low-income Maputo, Mozambique. qPCR assays were performed on 163 flies to carry out this research on the premise of genotypic resistance assays; this functions to derive antibiotic resistance genes (ARG) data for different antibiotic classes for Enterobacteriaceae. Standard culturing protocols and the Kirby-Bauer disk diffusion method was utilized to characterize the phenotypic resistance. In all, 49 isolates (18 Enterobacter aerogenes, 16 Escherichia coli and 12 Salmonella Enteritidis) were resistant to a wide array of antibiotics under cefotaxime and no cefotaxime conditions (table 2)16,23. Most of the isolates of the three bacterial species were resistant to streptomycin, chloramphenicol, and ceftazadime-Avibactam (table 2). As, many as 60.9% of the Enterobacteriaceae strains showed multidrug resistance (MDR). MDR gives rise to a barrier in controlling diseases, decreasing the number and effectiveness of treatment options. The high rate of antimicrobial resistance in bacterial isolates from flies may have major implications for both human and animal health especially in low to middle-income countries where the poor sanitation presents a prevalence of ARGs.
Error bounds for Lie group representations in quantum mechanics
Creators: name: Van Luijk, Lauritz
name: Galke, Niklas
name: Hahn, Alexander
name: Burgarth, Daniel
Publisher: name: Bristol : IOP Publ.
Year: 2024
Subjects: subject: energy constrained
subject: error bounds
subject: Lie groups
subject: projective representation
subject: unitary representations
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: We provide state-dependent error bounds for strongly continuous unitary representations of connected Lie groups. That is, we bound the difference of two unitaries applied to a state in terms of the energy with respect to a reference Hamiltonian associated with the representation and a left-invariant metric distance on the group. Our method works for any connected Lie group, and the metric is independent of the chosen representation. The approach also applies to projective representations and allows us to provide bounds on the energy-constrained diamond norm distance of any suitably continuous channel representation of the group.
Characterizing the Accessibility, Safety, and Marketing of Oxycodone Sold Online Without Prescription Requirements in the United States: A Cross-sectional Study
Creators: name: Goti, Noelia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Introduction: Oxycodone is a semi-synthetic opioid listed as a Schedule II-controlled substance due to its highly addictive properties and harmful adverse effects when abused or misused. This study evaluated the accessibility of oxycodone from online pharmacies identified through common search engines.

Methods: Two phrases “buy oxycodone online” and “buy Percocet online” were used to search the first 100 websites appearing among four common search engines (Google, Yahoo, Bing, DuckDuckGo) to identify unique online pharmacies selling oxycodone. Online pharmacies were included if they sold a dosage form of oxycodone, had a unique URL, and shipped within the US. Identified pharmacies were then categorized as “rogue”, “unclassified”, or “legitimate” using LegitScript’s classification. Safety, marketing, and cost characteristics were collected upon review of each online pharmacy found to sell oxycodone.

Results: A total of 110 unique website URLs were identified, leading to 50 unique online pharmacies. Of the 50 online pharmacies, 40 were rogue without a prescription requirement, nine were unclassified by LegitScript, and only one was legitimate abiding by US laws and regulations. Rogue and unclassified pharmacies were similar in their failure to promote patient safety, as none of them required a prescription, had no limit on the quantity sold, and did not require a health-related questionnaire before purchase. The marketing tactics used by both rogue and unclassified pharmacies were similar to one another in their attempts to lure customers to their websites. While rogue and unclassified pharmacies provided basic customer service (offering to speak with an associate, providing a phone number, and showing customer testimonies), none of them were registered with professional organizations.

Conclusions: Despite regulations and measures taken thus far, rogue online pharmacies continue to be pervasive among common search engines. Rogue online pharmacies are found to be easily accessible through common search engines, with many lacking common safeguards that would prevent dangerous risks individuals may face by taking oxycodone. A collective effort must be made between the federal government, regulatory agencies, search engine companies and global leaders to combat the risks posed by rogue pharmacies.
Evaluating episodic sediment deposition zones in freshwater mussel habitats across Missouri, USA
Creators: name: Sun, Qingqing
name: Wang, Binbin
name: Sansom, Brandon J.
name: Trauth, Kathleen
name: Brown, Henry
name: Zhu, Wenyu
name: Kunz, James
name: Barnhart, M. Chris
name: McMurray, Stephen
name: Roberts, Andrew D.
name: Shulse, Christopher D.
name: Knerr, Caleb J.
name: Steevens, Jeffery A.
name: Deng, Baolin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Point-source sedimentation, such as spills from construction-related activities, can introduce substantial sediments into streams in the short term, potentially leading to mussel burial. To estimate downstream areas where freshwater mussels might face threats from sediment burial within the mussel habitats of Missouri streams and rivers, we examined 49 reaches where both field measurements and gaging data are available. We established empirical relationships for three flow classes to represent general flow conditions of all reaches. Using these hydraulic data, we employed a Lagrangian particle tracking model to simulate sediment transport under each condition, employing two sediment size ranges covering very fine sands to small gravels, resulting in 72 simulated scenarios. The model results indicate that sediments with diameters exceeding a critical value, ranging from 0.041 to 1.975 mm for varying velocities (ranging from 0.124 to 2.191 m/s) and depths (ranging from 1 to 12 m), settle in downstream locations. Potential settling sites span from tens to hundreds of meters downstream. The mode, median, and mean of sediment distribution generally fall within the range of 10–200 m based on particle count, while these values typically range from 1 to 100 m based on sediment mass.
Polypharmacy in U.S. Medicare Beneficiaries with Antineutrophil Cytoplasmic Antibody (ANCA) Vasculitis
Creators: name: Cao, Binxin (Bessie)
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Background: Treatment requirements of antineutrophil cytoplasmic autoantibody vasculitis (AV) and high comorbidity burden among AV patients may lead to higher potential for polypharmacy (i.e., taking ≥5 medications concurrently) and its associated adverse outcomes, including adverse drug events, nonadherence, drug-drug interactions, and higher costs. Medication burden and risk factors associated with polypharmacy in AV patients have not been well-characterized. 

Objective: To characterize medication burden and examine prevalence of and risk factors for polypharmacy in the first year after diagnosis with AV.

Methods: We conducted a retrospective cohort study using 2015-17 Medicare claims to identify incident cases of AV. We counted number of unique generic products dispensed to patients in each of four quarters after diagnosis, and categorized medication count as high (≥10 medications), moderate (5-9 medications), or no polypharmacy (<5 medications). We used multinomial logistic regression to examine associations of predisposing, enabling, and medical need factors with having high or moderate polypharmacy.

Results: In 1,239 Medicare beneficiaries with AV, polypharmacy was most common in the first quarter (Q1) after diagnosis (83.7%), with 43.2% taking 5-9 medications and 40.5% taking ≥10. The odds of high polypharmacy were greater in all quarters for patients with eosinophilic granulomatosis with polyangiitis (EGPA) compared to granulomatosis with polyangiitis (GPA), ranging from 2.02 (95% CI: 1.18, 3.46) in Q3 to 2.89 (95% CI: 1.62, 5.12) in Q4. Older age, diabetes, chronic kidney disease (CKD), obesity, a higher Charlson comorbidity index (CCI) score, coverage with Medicaid/Part D low-income subsidy, and living in areas with low education or persistent poverty were risk factors for polypharmacy.
title: Rotating optical catheter tip for optical coherence tomography
Creators: name: Feldman, Marc D.
name: Milner, Thomas E.
name: Oh, Jung-Hwan
name: Castella, Paul C.
name: Chen, Shaochen
Publisher: name: United States Patent and Trademark Office
Year: 2010
Subjects: subject: A61B5/0066
subject: A61B1/00183
subject: A61B5/0084
subject: A61B5/6852
subject: A61B6/12
subject: A61B8/12
subject: A61B8/4461
subject: A61M25/0074
subject: A61B1/3137
subject: A61M2202/0476
subject: A61N2007/0091
subject: 600/478
subject: 600/182
subject: 600/473

description: The present invention relates to a rotating catheter tip for optical coherence tomography based on the use of an optical fiber that does not rotate, that is enclosed in a catheter, which has a tip rotates under the influence of a fluid drive system to redirect light from the fiber to a surrounding vessel and the light reflected or backscattered from the vessel back to the optical fiber.
Additional file 1 of Illness perceptions, fear of progression and health-related quality of life during acute treatment and follow-up care in paediatric cancer patients and their parents: a cross-sectional study
Creators: name: Herzog, Kristina
name: Schepper, Florian
name: Pletschko, Thomas
name: Herrmann, Jessy
name: Budich, Mihaela
name: Christiansen, Holger
name: Suttorp, Meinolf
name: Martini, Julia
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 1. Descriptive results (M, SD) of IPQ-R, FoP-Q-SF, and KINDL-R, by stage of medical treatment.
Supplemental_Appendix – Supplemental material for Local and Standardized Strategies: A Content Analysis of Newspaper Food and Beverage Advertising in Jamaica
Creators: name: Ahn, Regina Jihea
name: Nelson, Michelle R.
name: Ferguson, Gail M.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, Supplemental_Appendix for Local and Standardized Strategies: A Content Analysis of Newspaper Food and Beverage Advertising in Jamaica by Regina Jihea Ahn, Michelle R. Nelson and Gail M. Ferguson in Newspaper Research Journal
Mind Matters: Effects of Mental Health on College Students’ Academic Achievement
Creators: name: Goodman, Gabriela
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Rates of anxiety and depression on college campuses are rising at an unprecedented rate. Analyzing longitudinal survey data and academic records from undergraduate students at a large public research university in the U.S., this paper investigates the relationships between mental health and the academic achievement of college students. Specifically, we first explore how anxiety and depression impact GPA and credit hours completed during a given term. We then assess whether pass/fail grading flexibility during the COVID-19 pandemic played a protective role in the relationship between mental health and academic achievement. Through our results, we find that both anxiety and depression decrease GPA and credit hours completed each semester, with depression generally having larger effects. Additionally, pass/fail usage during the pandemic has a negative impact on Fall 2021 GPA, with these negative effects exacerbated for individuals experiencing anxiety and depression.
A monolithic space–time temporal multirate finite element framework for interface and volume coupled problems
Creators: name: Roth, Julian
name: Soszyńska, Martyna
name: Richter, Thomas
name: Wick, Thomas
Publisher: name: Amsterdam [u.a.] : North-Holland
Year: 2024
Subjects: subject: Galerkin space–time
subject: Interface coupling
subject: Mandel's benchmark
subject: Monolithic framework
subject: Multirate
subject: Volume coupling
subject: Dewey Decimal Classification::500 | Naturwissenschaften::510 | Mathematik

description: In this work, we propose and computationally investigate a monolithic space–time multirate scheme for coupled problems. The novelty lies in the monolithic formulation of the multirate approach as this requires a careful design of the functional framework, corresponding discretization, and implementation. Our method of choice is a tensor-product Galerkin space–time discretization. The developments are carried out for both prototype interface- and volume coupled problems such as coupled wave-heat-problems and a displacement equation coupled to Darcy flow in a poro-elastic medium. The latter is applied to the well-known Mandel's benchmark and a three-dimensional footing problem. Detailed computational investigations and convergence analyses give evidence that our monolithic multirate framework performs well.
Queer Aesthetics: Oscar Wilde and the Development of the "Queer Artist"
Creators: name: Leo Bautista
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Oscar Wilde has long been regarded as a queer icon—his highly publicized 1895 trial was integral in providing the public with an understanding (if a limited and stereotypical one) of homosexual identity. Significant work has been done with regards to how Wilde’s sexual identity would have been influenced and shaped by the society in which he lived, as well as Wilde’s impact on the creation of the figure of the homosexual. However, little academic work has been done to investigate how Wilde’s sexual identity influenced his philosophies on art, and by extension, his figure of the ideal artist. Thus, this thesis explores the development of the archetype of “the Artist” in Wilde’s works, interpreting this archetype through the lens of Wilde’s own understanding of his sexuality and his artistic philosophies. Chapter 1 considers Wilde’s engagement with the philosophies of two incredibly influential figures: Walter Pater and John Addington Symonds. Chapter 2 examines the character of Cyril Graham from Wilde’s short story “The Portrait of Mr. W.H.,” discussing the ways in which Cyril both exemplifies and contradicts the ideals set forth by Wilde’s aforementioned mentors. Finally, Chapter 3 explores Basil Hallward from Wilde’s most famous work, The Picture of Dorian Gray, the most famous and archetypical of Wilde’s Artist characters. Ultimately, this reading allows us to examine Wilde’s work through a kind of proto-queer theory lens, granting us insight into the ways in which queer desire shapes one’s worldview and philosophies, with sexuality having much greater and more far-reaching consequences than merely determining to whom one is attracted.
dust
Creators: name: Jimenez, Sergia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Dust is an exploration of ritual, repetition, and patience in the age of image addiction. The exhibition is composed of three elements: video and sculpture work dealing with slow attentiveness and patience, a photographic installation documenting my ritual practice of searching and documenting for moments of rest in my everyday life, and a series of sound works that attempt to investigate silences. “Dust” asks the viewer to slow down, be present, and imagine what a restful life might be like.
Automatic Flood Detection from Sentinel-1 Data Using a Nested UNet Model and a NASA Benchmark Dataset
Creators: name: Ghosh, Binayak
name: Garg, Shagun
name: Motagh, Mahdi
name: Martinis, Sandro
Publisher: name: [Cham] : Springer International Publishing
Year: 2024
Subjects: subject: Deep learning
subject: Flood detection
subject: NASA
subject: Synthetic aperture radar
subject: Transfer learning
subject: UNet
subject: UNet++
subject: Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaften

description: During flood events near real-time, synthetic aperture radar (SAR) satellite imagery has proven to be an efficient management tool for disaster management authorities. However, one of the challenges is accurate classification and segmentation of flooded water. A common method of SAR-based flood mapping is binary segmentation by thresholding, but this method is limited due to the effects of backscatter, geographical area, and surface characterstics. Recent advancements in deep learning algorithms for image segmentation have demonstrated excellent potential for improving flood detection. In this paper, we present a deep learning approach with a nested UNet architecture based on a backbone of EfficientNet-B7 by leveraging a publicly available Sentinel‑1 dataset provided jointly by NASA and the IEEE GRSS Committee. The performance of the nested UNet model was compared with several other UNet-based convolutional neural network architectures. The models were trained on flood events from Nebraska and North Alabama in the USA, Bangladesh, and Florence, Italy. Finally, the generalization capacity of the trained nested UNet model was compared to the other architectures by testing on Sentinel‑1 data from flood events of varied geographical regions such as Spain, India, and Vietnam. The impact of using different polarization band combinations of input data on the segmentation capabilities of the nested UNet and other models is also evaluated using Shapley scores. The results of these experiments show that the UNet model architectures perform comparably to the UNet++ with EfficientNet-B7 backbone for both the NASA dataset as well as the other test cases. Therefore, it can be inferred that these models can be trained on certain flood events provided in the dataset and used for flood detection in other geographical areas, thus proving the transferability of these models. However, the effect of polarization still varies across different test cases from around the world in terms of performance; the model trained with the combinations of individual bands, VV and VH, and polarization ratios gives the best results.
Additional file 1 of Pre-exposure prophylaxis (PrEP) for HIV prevention among people who inject drugs: a global mapping of service delivery
Creators: name: Shaw, Graham
name: Schaefer, Robin
name: Schmidt, Heather-Marie A
name: Madden, Annie
name: Chang, Judy
name: Mozalevskis, Antons
name: Msimanga-Radebe, Busisiwe
name: Mangadan Konath, Nabeel
name: Verster, Annette
name: Baggaley, Rachel
name: Rodolph, Michelle
name: Macdonald, Virginia
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Details on methods.
Investigating metabolomic pathways related to the association between red and processed meat consumption and insulin resistance
Creators: name: Shetye, Aditya
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Noncommunicable diseases, such as cardiometabolic diseases, were responsible for approximately 63% of annual deaths worldwide. Insulin resistance (IR) is identified as an important contributor to cardiovascular disease risk and metabolic disorders such as type 2 diabetes mellitus (T2DM). Although associations between lifestyle behaviors such as caloric intake, physical activity, genetic predisposition, and age have been observed with IR, less is known about mechanistic drivers linking IR to hyperglycemia. A common dietary behavior associated with metabolic syndrome (MetS), obesity, and increased IR is higher red meat consumption. However, the complexity of interactions between lifestyle behaviors and cardiometabolic markers of risk have stagnated conclusive associations between pathways relating to red and processed meat (RPM) intake and IR. Metabolomics provides information about circulating metabolites in the bloodstream, offering additional information beyond self-reported diet measures. Metabolomics may also shed light on individual variability in metabolic risk. In this cross-sectional study, we will investigate the role of metabolite peaks and metabolomic pathways that potentially underlie the positive association between red and processed meat consumption and insulin resistance within the year 20 (2005-06) cohort of the Coronary Artery Risk Development in Young Adults (CARDIA) study. After processing metabolite peak data through a series of multiple regression models and the Mummichog algorithm, 2 overlapping statistically significant metabolic pathways enriched by HOMA-IR, TG/HDL-C ratios, and total Red and Processed Meat intake were observed. These pathways included valine, leucine, and isoleucine degradation and alanine, aspartate, and glutamate metabolism. This study accomplished preliminary efforts to inform knowledge of metabolic pathways with potential to uncover associations between red and processed meat consumption and insulin resistance. Moreover, this study advocates for the use of untargeted metabolomics in determining mechanistic links between various diet patterns and disease progression.
title: System and method of resolving discrepancies between diverse firewall designs
Creators: name: Gouda, Mohamed G.
name: Liu, Xiang-Yang Alex
Publisher: name: United States Patent and Trademark Office
Year: 2011
Subjects: subject: H04L63/0263
subject: 709/224
subject: 713/155
subject: 726/11
subject: 726/1
subject: 726/22

description: A system, computer-implementable method, and computer-usable medium for resolving discrepancies between diverse firewall designs. In a preferred embodiment of the present invention, a firewall design manager receives at least two designs for a rule-based system and computing at least one functional discrepancy between the at least two designs utilizing decision diagrams.