cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Properties of doubly heavy baryons in QCD
Creators: name: Aliev, T. M.
name: Bilmis, S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The study of the properties of doubly heavy baryons represents a promising area in particle physics. It can provide us with information about Cabibbo-Kobayashi-Maskawa (CKM) matrix elements and the low energy dynamics of QCD. They have a very rich phenomenology. The investigation of weak, electromagnetic, and strong decays has vital importance for understanding the dynamics of doubly heavy baryons. The main ingredients of such studies are the spectroscopic parameters, the strong coupling constants, and the transition form factors. For calculations of these quantities, non-perturbative methods are needed. One of these methods is the QCD sum rules. In the present work, we review our studies on the properties of the doubly heavy baryons within the sum rules method, focusing mainly on the mass and strong coupling constants of the doubly heavy baryons. In addition, the radiative decays of doubly heavy baryons are estimated using the vector dominance model. We also make few remarks on the semileptonic decays of the doubly heavy baryons.
description: Review, 31 pages
(3515) Roger Cunliffe
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
LA HUELLA DEL MAL leer el libro pdf
Creators: name: Binder
Publisher: name: Zenodo
Year: 2024

description: LA HUELLA DEL MAL de MANUEL RIOS SAN MARTIN

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LA HUELLA DEL MAL

MANUEL RIOS SAN MARTIN

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788408283683

Editorial: PLANETA

Año de edición: 2024

 

 

 

 

 

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Overview

Un yacimiento mítico, un asesinato desconcertante, una pareja de investigadores con un pasado secreto.En una visita a Atapuerca, un estudiante descubre que una de las reproducciones humanas que imitan los enterramientos de los homínidos de hace miles de años es, en realidad, el cuerpo de una chica muerta. La joven parece haber sido colocada con una simbología ritual, y todas las pistas apuntan a un macabro homicidio ocurrido seis años atrás en otro yacimiento, en Asturias. Demasiados detalles recuerdan al caso anterior, por lo que el juez piensa en reunir de nuevo a los policías que se hicieron cargo entonces: la inspectora Silvia Guzmán y Daniel Velarde, un expolicía dedicado ahora a la seguridad privada. Pero nadie sabe que hace tiempo ambos vivieron una relación que tuvo mucho que ver con la truncada resolución del caso. Ahora, Silvia y Daniel deberán colaborar y aclarar sus sentimientos para descubrir al asesino del yacimiento y cerrar aquella herida abierta en su pasado. ENFRÉNTATE A LA VERDAD.
Download Pdf For 100 Days: A Steamy Billionaire Romance Novel: by Lara Adrian
Creators: name: Brown
Publisher: name: Zenodo
Year: 2024

description: For 100 Days: A Steamy Billionaire Romance Novel: by Lara Adrian

 

 

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For 100 Days: A Steamy Billionaire Romance Novel:

Lara Adrian

Page: 368

Format: pdf, ePub, mobi, fb2

ISBN: 9798881164843

Publisher: Barnes & Noble Press

 

Free e book pdf download For 100 Days: A Steamy Billionaire Romance Novel: 9798881164843 English version by Lara Adrian CHM

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Additional file 1 of Budget impact analysis of a digital monitoring platform for COPD
Creators: name: Inocencio, Timothy J.
name: Sterling, Kimberly L.
name: Sayiner, Sibel
name: Minshall, Michael E.
name: Kaye, Leanne
name: Hatipoğlu, Umur
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Supplementary Methods: Section 1.1 Medical Healthcare Resource Use Inputs; Section 1.2 Inhaler Medication Use and Associated Unit Cost Inputs; Section 1.3 Effect of Propeller on Medical HCRU; Table S1. Annual per-patient estimated cost by enrolment status and severity for commercial payers; Table S2. Annual per-patient estimated cost by enrolment status and severity for Medicare.
{epub descargar} PRIMERO LLEGÓ EL ESCÁNDALO
Creators: name: Batiste
Publisher: name: Zenodo
Year: 2024

description: PRIMERO LLEGÓ EL ESCÁNDALO de JULIA QUINN

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PRIMERO LLEGÓ EL ESCÁNDALO

JULIA QUINN

Número de páginas: 320

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788418480416

Editorial: TITANIA

Año de edición: 2021

 

 

 

 

 

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Overview

Ella tenía dos opciones…Georgiana Bridgerton no está en contra de la idea del matrimonio. Simplemente pensaba que, cuando llegara el momento, podría decidir. Pero con su reputación pendiendo de un hilo tras haber sido secuestrada, Georgie solo tiene dos opciones: quedarse soltera para siempre o casarse con el canalla que le ha arruinado la vida.Pero entra en juego una tercera opción.Nicholas Rokesby, cuarto hijo de un conde, está preparado para labrarse su propio camino. Vive en Edimburgo, donde está a punto de acabar sus estudios de medicina, y no tiene ni tiempo ni interés por encontrar esposa. Pero cuando descubre que Georgie Bridgerton, su vecina de toda la vida, se enfrenta a un futuro incierto, sabe lo que tiene que hacer.Un matrimonio de convenienciaQuizás no ha sido la proposición matrimonial más romántica del mundo, pero Nicholas nunca pensó que ella diría que no. Georgie no quiere que nadie se sacrifique por ella, y además, ellos dos nunca pensaron el uno en el otro como nada más que amigos de la infancia… ¿o sí? Pero mientras se embarcan en un cortejo poco convencional, descubren un nuevo giro de su lejana relación. Primero llegó el escándalo, luego el matrimonio, pero después… después llegó el amor.
Homogeneous spectroscopic parameters for bright planet host stars from the northern hemisphere
Creators: name: Sousa, S. G.
name: Santos, N. C.
name: Mortier, A.
name: Tsantaki, M.
name: Adibekyan, V.
name: Mena, E. Delgado
name: Israelian, G.
name: Rojas-Ayala, B.
name: Neves, V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Aims. In this work we derive new precise and homogeneous parameters for 37 stars with planets. For this purpose, we analyze high resolution spectra obtained by the NARVAL spectrograph for a sample composed of bright planet host stars in the northern hemisphere. The new parameters are included in the SWEET-Cat online catalogue. Methods. To ensure that the catalogue is homogeneous, we use our standard spectroscopic analysis procedure, ARES+MOOG, to derive effective temperatures, surface gravities, and metallicities. These spectroscopic stellar parameters are then used as input to compute the stellar mass and radius, which are fundamental for the derivation of the planetary mass and radius. Results. We show that the spectroscopic parameters, masses, and radii are generally in good agreement with the values available in online databases of exoplanets. There are some exceptions, especially for the evolved stars. These are analyzed in detail focusing on the effect of the stellar mass on the derived planetary mass. Conclusions. We conclude that the stellar mass estimations for giant stars should be managed with extreme caution when using them to compute the planetary masses. We report examples within this sample where the differences in planetary mass can be as high as 100% in the most extreme cases.
description: 6 pages; 3 Figures, 2 Tables in appendix; Accepted for A&A
Nutrigenomics, the microbiome, and gene-environment interactions: New directions in cardiovascular disease research, prevention, and treatment
Creators: name: Gerszten, R.E.
name: Rimm, E.B.
name: Ordovás, J.M.
name: Bennett, B.J.
name: Wang, T.J.
name: Allayee, H.
name: Kris-Etherton, P.M.
name: Ideraabdullah, F.
name: Ferguson, J.F.
Publisher: name: Lippincott Williams and Wilkins
Year: 2016

description: Cardiometabolic diseases are the leading cause of death worldwide and are strongly linked to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple approaches aimed at understanding the effects of diet on health or disease development, including nutrigenetic studies investigating the relationship between genetic variants and diet in modulating cardiometabolic risk, as well as the effects of dietary components on multiple "omic" measures, including transcriptomics, metabolomics, proteomics, lipidomics, epigenetic modifications, and the microbiome. Here, we describe the current state of the field of nutrigenomics with respect to cardiometabolic disease research and outline a direction for the integration of multiple omics techniques in future nutrigenomic studies aimed at understanding mechanisms and developing new therapeutic options for cardiometabolic disease treatment and prevention.
Novel cis-regulatory function in ICR-mediated imprinted repression of H19
Creators: name: Thorvaldsen, J.L.
name: Ideraabdullah, F.Y.
name: Engel, N.
name: Bartolomei, M.S.
name: Wen, S.C.
name: Krapp, C.
name: Abramowitz, L.K.
Publisher: name: Academic Press Inc.
Year: 2011

description: Expression of coregulated imprinted genes, H19 and Igf2, is monoallelic and parent-of-origin-dependent. Like most imprinted genes, H19 and Igf2 are regulated by a differentially methylated imprinting control region (ICR). CTCF binding sites and DNA methylation at the ICR have previously been identified as key cis-acting elements required for proper H19/Igf2 imprinting. Here, we use mouse models to elucidate further the mechanism of ICR-mediated gene regulation. We specifically address the question of whether sequences outside of CTCF sites at the ICR are required for paternal H19 repression. To this end, we generated two types of mutant ICRs in the mouse: (i) deletion of intervening sequence between CTCF sites (H19ICR-IVS), which changes size and CpG content at the ICR; and (ii) CpG depletion outside of CTCF sites (H19ICR-8nrCG), which only changes CpG content at the ICR. Individually, both mutant alleles (H19ICR-IVS and H19ICR-8nrCG) show loss of imprinted repression of paternal H19. Interestingly, this loss of repression does not coincide with a detectable change in methylation at the H19 ICR or promoter. Thus, neither intact CTCF sites nor hypermethylation at the ICR is sufficient for maintaining the fully repressed state of the paternal H19 allele. Our findings demonstrate, for the first time in vivo, that sequence outside of CTCF sites at the ICR is required in cis for ICR-mediated imprinted repression at the H19/Igf2 locus. In addition, these results strongly implicate a novel role of ICR size and CpG density in paternal H19 repression.
title:  Benjamin, donne moderne e cinema hollywoodiano
Creators: name: Pravadelli, Veronica
Publisher: name: Roma TrE-Press
Year: 2016

description: Negli ultimi vent’anni, soprattutto nel contesto americano, le teorie di Walter Benjamin hanno costituito un elemento fondamentale nello sviluppo degli studi di cinema in relazione alla modernità. Particolare rilievo ha avuto la nozione benjaminiana di shock, ovvero la peculiare ricezione che il film, in virtù del suo dispositivo, attiva nello spettatore. Poco peso è stato dato, invece, alle teorie di Benjamin sulla femminilità. Questo intervento si propone di fondere queste due linee di ricerca del filosofo tedesco, per analizzare il cinema americano tra fine anni ’20 e inizio anni ’30. In particolare, il saggio andrà a scandagliare quello che è divenuto uno snodo fondamentale della riflessione sulla formazione del soggetto moderno, ovvero il rapporto fra femminilità e rappresentazione cinematografica. In questa prospettiva ci si concentrerà sulla messa in scena della working girl in alcuni film particolarmente significativi come per esempio Baby Face (1933).
description: Modernità nelle Americhe
Genomic imprinting mechanisms in mammals
Creators: name: Vigneau, S.
name: Ideraabdullah, F.Y.
name: Bartolomei, M.S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Genomic imprinting is a form of epigenetic gene regulation that results in expression from a single allele in a parent-of-origin-dependent manner. This form of monoallelic expression affects a small but growing number of genes and is essential to normal mammalian development. Despite extensive studies and some major breakthroughs regarding this intriguing phenomenon, we have not yet fully characterized the underlying molecular mechanisms of genomic imprinting. This is in part due to the complexity of the system in that the epigenetic markings required for proper imprinting must be established in the germline, maintained throughout development, and then erased before being re-established in the next generation's germline. Furthermore, imprinted gene expression is often tissue or stage-specific. It has also become clear that while imprinted loci across the genome seem to rely consistently on epigenetic markings of DNA methylation and/or histone modifications to discern parental alleles, the regulatory activities underlying these markings vary among loci. Here, we discuss different modes of imprinting regulation in mammals and how perturbations of these systems result in human disease. We focus on the mechanism of genomic imprinting mediated by insulators as is present at the H19/Igf2 locus, and by non-coding RNA present at the Igf2r and Kcnq1 loci. In addition to imprinting mechanisms at autosomal loci, what is known about imprinted X-chromosome inactivation and how it compares to autosomal imprinting is also discussed. Overall, this review summarizes many years of imprinting research, while pointing out exciting new discoveries that further elucidate the mechanism of genomic imprinting, and speculating on areas that require further investigation.
[PDF/Kindle] Chronique du tueur de roi Tome 2 by Patrick Rothfuss
Creators: name: Colmenero
Publisher: name: Zenodo
Year: 2024

description: Chronique du tueur de roi Tome 2 pan Patrick Rothfuss

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Caractéristiques

Chronique du tueur de roi Tome 2

Patrick Rothfuss

Nb. de pages: 573

Format: Pdf, ePub, MOBI, FB2

ISBN: 9782352946380

Editeur: Bragelonne

Date de parution: 2013

 

 

 

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Overview

J’ai libéré des princesses. J’ai incendié la ville de Trebon. J’ai suivi des pistes au clair de lune que personne n’ose évoquer durant le jour. J’ai conversé avec des dieux, aimé des femmes et écrit des chansons qui font pleurer les ménestrels. Mon nom est Kvothe. Vous avez dû entendre parler de moi. Le jour se lève sur l’auberge de La Pierre levée et l’homme reprend son récit, fidèle à sa promesse. Suivez ses pas sur la voie qui mène à l’héroïsme et à la déchéance. Découvrez la vérité qui a créé la légende.
Read [pdf]> Comedy Book: How Comedy Conquered Culture-and the Magic That Makes It Work by Jesse David Fox
Creators: name: Gordon
Publisher: name: Zenodo
Year: 2024

description: Comedy Book: How Comedy Conquered Culture-and the Magic That Makes It Work by Jesse David Fox

 

 

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Comedy Book: How Comedy Conquered Culture-and the Magic That Makes It Work

Jesse David Fox

Page: 368

Format: pdf, ePub, mobi, fb2

ISBN: 9780374604714

Publisher: Farrar, Straus and Giroux

 

Ebook torrent downloads free Comedy Book: How Comedy Conquered Culture-and the Magic That Makes It Work PDF (English literature) 9780374604714 by Jesse David Fox

Comedy Book: How Comedy Conquered Culture–and the Named a Most Anticipated Book by Vulture, Elle, Chicago Tribune, The Millions, and Lit Hub"Comedy Book changes the way we talk about an art form that is  Comedy Book - Macmillan How Comedy Conquered Culture–and the Magic That Makes It Work · Comedy Book · $29.00 · $29.00 · Reviews from Goodreads · About This Book. Books - Best Comedy Comedy Book: How Comedy Conquered Culture–and the Magic That Makes It Work. 1  65 Best Comedy Books Based on over 200 original interviews and extensive archival research, this sharply written and highly entertaining book is a must-read for anyone interested in  https://www.edelweiss.plus/?sku=0374604711&g=4400 Pop Culture - New Releases Comedy Book: How Comedy Conquered Culture–and the Magic That Makes It Work. 1  How Comedy Conquered Culture- Named a Most Anticipated Book by Vulture, Elle, Chicago Tribune, The Millions, and Lit Hub"Comedy Book changes the way we talk about an art form that is  Untitled Loading Preload Domine font. 楽天Kobo電子書籍ストア: Comedy Book - Jesse David Fox Comedy Book How Comedy Conquered Culture?and the Magic That Makes It Work (Farrar, Straus and Giroux) [電子書籍版] · 発行形態: · 電子書籍 (楽天Kobo). How Comedy Conquered Culture-And the Magic That In Comedy Book, Jesse David Fox--the country's most definitive voice in comedy criticism and someone who, in his own words, "enjoys comedy maybe more than  How Comedy Conquered Culture?and the Magic That (Read Now) Comedy Book: How Comedy Conquered Culture?and the Magic That Makes It Work by Jesse David FoxComedy Book: How Comedy Conquered Culture?and the  White Bird: A Wonder Story | Solano County Library Based on the book by the best-selling author of Wonder, this uplifting movie shows how one act of kindness can live on forever. DVD. unavailable. How Comedy Conquered Culture—And the Magic That Comedy Book: How Comedy Conquered Culture—And the Magic That Makes It Work · Jesse David Fox. Farrar, Straus and Giroux, $29 (368p) ISBN 978-0-  How Comedy Conquered Culture–and the Magic That Comedy Book: How Comedy Conquered Culture–and the Magic That Makes It Work (Hardcover) ; Publication Date: November 7th, 2023 ; Pages: 368 ; Language: English. Comedy Book - By: Jesse David Fox Buy the eBook Comedy Book, How Comedy Conquered Culture-and the Magic That Makes It Work by Jesse David Fox online from Australia's leading online eBook
Radial graphs of constant curvature and prescribed boundary
Creators: name: Cruz, Flávio F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 53A10, 53C42

description: In this paper we are concerned with the problem of finding hypersurfaces of constant curvature and prescribed boundary in the Euclidean space, using the theory of fully nonlinear elliptic equations. We prove that if the given data admits a suitable radial graph as a subsolution, then we can find a radial graph with constant curvature and that realizes the prescribed boundary. As an application we prove that if $Ω\subset\mathbb{S}^n$ is a mean convex domain whose closure is contained in an open hemisphere of $\mathbb{S}^n$ then, for $0
description: 19 pages. Revised version. To appear in Calculus of Variations and Partial Differential Equations
Weathering the Storm: Managing Older Adults With Breast Cancer Amid COVID-19 and Beyond
Creators: name: King, T.A.
name: Minami, C.
name: Lin, N.U.
name: Sedrak, M.S.
name: Jolly, T.A.
name: Muss, H.B.
name: VanderWalde, N.
name: Freedman, R.A.
name: Bellon, J.R.
name: Block, C.C.
name: Winer, E.P.
Publisher: name: NLM (Medline)
Year: 2021

description: Caring for older patients with breast cancer presents unique clinical considerations because of preexisting and competing comorbidity, the potential for treatment-related toxicity, and the consequent impact on functional status. In the context of the COVID-19 pandemic, treatment decision making for older patients is especially challenging and encourages us to refocus our treatment priorities. While we work to avoid treatment delays and maintain therapeutic benefit, we also need to minimize the risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposures, myelosuppression, general chemotherapy toxicity, and functional decline. Herein, we propose multidisciplinary care considerations for the aging patient with breast cancer, with the goal to promote a team-based, multidisciplinary treatment approach during the COVID-19 pandemic and beyond. These considerations remain relevant as we navigate the "new normal" for the approximately 30% of breast cancer patients aged 70 years and older who are diagnosed in the United States annually and for the thousands of older patients living with recurrent and/or metastatic disease.
Descargar ebook PIZARRAS DE LA HISTORIA DEL MUNDO | Descarga Libros Gratis (PDF - EPUB)
Creators: name: Mangum
Publisher: name: Zenodo
Year: 2024

description: PIZARRAS DE LA HISTORIA DEL MUNDO de GIL GONZALEZ SOFIA

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Ficha técnica

PIZARRAS DE LA HISTORIA DEL MUNDO

GIL GONZALEZ SOFIA

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788413847061

Editorial: LA ESFERA DE LOS LIBROS

Año de edición: 2023

 

 

 

 

 

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Overview

¿Te imaginas poder ver un imperio en su apogeo, una revolución en pleno desarrollo o una guerra mundial con solo cerrar los ojos?Ya seas un estudiante ansioso por aprender, un profesor en busca de un enfoque fresco o un apasionado de la historia, las Pizarras transformarán la forma en que percibes y recuerdas el pasado. En estas páginas, que van desde las primeras civilizaciones hasta el enfrentamiento de la Guerra Fría, encontrarás una vista panorámica de las ideas clave y las conexiones fundamentales que definen cada período que conforma la Historia de nuestro mundo.Las Pizarras de la Historia no aspiran a ser una enciclopedia exhaustiva ni a reemplazar tus manuales de historia, en cambio, están diseñadas para divertirte y ayudarte a conocer aquello que no sabías.
(3508) Irina Tennant
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Proses Penerbitan Artikel
Creators: name: Wekke, Ismail Suardi
name: Herianto, Herianto
Publisher: name: Zenodo
Year: 2020

description: Modul #1 Proses Penerbitan Artikel. Journal Mistar, diterbitkan Himpunan Mahasiswa Islam, Komisariat Tarbiyah dan Keguruan, Cabang Gowa Raya
Entrepreneurial ventures’ market choices: essays from the solar photovoltaic industry
Creators: name: Guerra, Mara
Publisher: name: Imperial College London
Year: 2020

description: This dissertation seeks to understand how entrepreneurial ventures make technology commercialization decisions on the product market and under conditions of demand heterogeneity Furthermore, it seeks to understand how entrepreneurial strategies unfold and their consequence for ventures and industry alike. To this end, I carry out three empirical studies of the solar photovoltaic industry. The first study explores the drivers of the decision to enter a niche product market. Despite the key role of niche markets for a disruptive strategy, we still know little about which ventures make this choice. I characterise mainstream and niche markets in terms of the different commercialization challenges to be encountered in each one of them. I find empirical support for the role of prior experience on having preferences for different commercialization challenges, underscoring the role of cognition on the decision to enter niche markets. In the second study, I explore the factors that lead ventures to enter markets with low technology-market fit. Grounding the commercialization journey of start-ups in the technology-to-market linking process, I study how industry-level factors can make the process cognitively more or less taxing. I find empirical support for the idea that increasing capital availability creates a bias that leads ventures towards poorly fitting markets, despite their belief to be making a promising choice. Moreover, I show that the more choices were previously made by other ventures, the easier it is to choose highly fitting markets. The third study focuses on how the strategies of dominant firms unfold over time and affect venture-level and industry- level outcomes. More specifically, I identify two strategies – a technology-driven one and a paradigm-driven one – that are critical to move the industry to early commercialization but set up conditions that prevent further uncertainty reduction to reach sales take-off and maturity, condemning the industry to a slow retrenchment.
Effects of breast cancer adjuvant chemotherapy regimens on expression of the aging biomarker, p16ink4a
Creators: name: Claire Dees, E.
name: Anders, C.K.
name: Karuturi, M.S.
name: Nyrop, K.A.
name: Reeder-Hayes, K.E.
name: Kimmick, G.G.
name: Carey, L.A.
name: Shachar, S.S.
name: Mitin, N.
name: Jolly, T.A.
name: Reinbolt, R.E.
name: Deal, A.M.
name: Speca, J.C.
name: Muss, H.B.
Publisher: name: Oxford University Press
Year: 2021

description: Background: Although chemotherapy saves lives, increasing evidence shows that chemotherapy accelerates aging. We previously demonstrated that mRNA expression of p16INK4a, a biomarker of senescence and molecular aging, increased early and dramatically after beginning adjuvant anthracycline-based regimens in early stage breast cancer patients. Here, we determined if changes in p16INK4a expression vary by chemotherapy regimen among early stage breast cancer patients. Methods: We conducted a study of stage I-III breast cancer patients receiving adjuvant or neoadjuvant chemotherapy. p16INK4a expression was analyzed prechemotherapy and postchemotherapy (median 6.2 months after the last chemotherapy) in peripheral blood T lymphocytes. Chemotherapy-induced change in p16INK4a expression was compared among regimens. All statistical tests were 2-sided. Results: In 146 women, chemotherapy was associated with a statistically significant increase in p16INK4a expression (accelerated aging of 17 years; P < .001). Anthracycline-based regimens were associated with the largest increases (accelerated aging of 23 to 26 years; P ≤ .008). Nonanthracycline-based regimens demonstrated a much smaller increase (accelerated aging of 9 to 11 years; P ≤ .15). In addition to the type of chemotherapy regimen, baseline p16INK4a levels, but not chronologic age or race, were also associated with the magnitude of increases in p16INK4a. Patients with lower p16INK4a levels at baseline were more likely to experience larger increases. Conclusions: Our findings suggest that the aging effects of chemotherapy may be influenced by both chemotherapy type and the patient's baseline p16INK4a level. Measurement of p16INK4a expression is not currently available in the clinic, but nonanthracycline regimens offering similar efficacy as anthracycline regimens might be favored.
Intensive Smoking Cessation Counseling for Patients with Cancer
Creators: name: Goldstein, A.O.
name: Jolly, T.A.
name: Shoenbill, K.A.
Publisher: name: American Medical Association
Year: 2020

description: Smoking remains the leading cause of preventable death in the United States. Tobacco use increases the risk of multiple cancers, including lung, oropharyngeal, pancreas, bladder, stomach, and colon. Continued tobacco use following a cancer diagnosis increases the risk of cancer recurrence, new primary cancers, and adverse treatment-related outcomes, including postoperative pulmonary complications, poor surgical healing, and decreased response to chemotherapeutic drugs.
Panicum hallii RIL population (HAL2 X FIL2 ) genetic map
Creators: name: Haque, Taslima
name: Juenger, Thomas
name: Schmutz, Jeremy
Publisher: name: Zenodo
Year: 2022

description: This project represents the method of constructing genetic map for the Panicum hallii Recombinant Inbreed Line (RIL) population. This population is a cross between one inland (HAL2) and one coastal (FIL2) natural accession of P. hallii. This map compromise of 441 RIL individuals genotyped for 901 markers. The raw sequences for RIL individuals are available in NCBI SRA archive Umbrella project PRJNA701489.
description: Funding provided by: NSF Plant Genome Research Program*
Crossref Funder Registry ID:
Award Number: ISO1444533
description: This data submitted here in this project is in R/qtl format.
[download pdf] Dark Succession (previously published as The Marriage Contract) by Katee Robert
Creators: name: Smith
Publisher: name: Zenodo
Year: 2024

description: Dark Succession (previously published as The Marriage Contract) by Katee Robert

 

 

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Dark Succession (previously published as The Marriage Contract)

Katee Robert

Page: 336

Format: pdf, ePub, mobi, fb2

ISBN: 9781538741047

Publisher: Grand Central Publishing

 

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Overview

The New York Times bestselling author of Radiant Sin delivers a smoking hot series about the O'Malley family—wealthy, powerful, dangerous and seething with scandal. Teague O'Malley hates everything associated with his family's name. And when his father orders him to marry Callista Sheridan to create a "business" alliance, Teague's ready to cut ties once and for all. But then Teague actually meets Callista, sees the bruises on her neck and the trauma in her eyes and vows he will do everything in his power to avenge her. Everyone knows the O'Malleys are dangerous. But Callie wasn't prepared for his brand of lethal grace and coiled power. His slightest touch scorches through her. But the closer they get, the more trouble they're in. Because Callie's keeping a dark secret—and what Teague doesn't know could get him killed.
Microwave-stimulated superconductivity due to presence of vortices
Creators: name: Lara, Antonio
name: Aliev, Farkhad G.
name: Silhanek, Alejandro V.
name: Moshchalkov, Victor V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The response of superconducting devices to electromagnetic radiation is a core concept implemented in diverse applications, ranging from the currently used voltage standard to single photon detectors in astronomy. Suprisingly, a sufficiently high power subgap radiation may stimulate superconductivity itself. The possibility of stimulating type II superconductors, in which the radiation may interact also with vortex cores, remains however unclear. Here we report on superconductivity enhanced by GHz radiation in type II superconducting Pb films in the presence of vortices. The stimulation effect is more clearly observed in the upper critical field and less pronounced in the critical temperature. The magnetic field dependence of the vortex related microwave losses in a film with periodic pinning reveals a reduced dissipation of mobile vortices in the stimulated regime due to a reduction of the core size. Results of numerical simulations support the validy of this conclusion. Our findings may have intriguing connections with holographic superconductors in which the possibility of stimulation is under current debate.
Read online: Star Wars The Rise and Fall of the Galactic Empire by Chris Kempshall
Creators: name: Johnson
Publisher: name: Zenodo
Year: 2024

description: Star Wars The Rise and Fall of the Galactic Empire by Chris Kempshall

 

 

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Star Wars The Rise and Fall of the Galactic Empire

Chris Kempshall

Page: 432

Format: pdf, ePub, mobi, fb2

ISBN: 9780744098822

Publisher: DK

 

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title:  La donna nuova americana nell’illustrazione: reazioni italiane tra Belle Époque e fascismo
Creators: name: Rossini, Daniela
Publisher: name: Roma TrE-Press
Year: 2016

description: L'irruzione della modernità americana sulla scena europea nei primi decenni del Novecento comprende l’immagine della ‘donna nuova’ americana. Si tratta di una donna istruita, autonoma, e determinata che occupa gli spazi pubblici della metropoli moderna in tutti gli ambiti. Come i grattacieli, questa nuova figura di donna provoca reazioni ugualmente forti di attrazione e di rifiuto. A prima vista sembra meno impressionante del suo contesto urbano. È però culturalmente più minacciosa, sia perché mette in discussione ruoli di genere consolidati, sia perché trova un’eco nelle contemporanee rivendicazioni dei movimenti femministi europei. Inoltre, la sua immagine si presta ad un uso pervasivo nei nuovi campi della stampa illustrata, della pubblicità, del cinema e dell’industria dell’intrattenimento in generale. Il contributo analizzerà le caratteristiche salienti dell’evoluzione della posizione delle donne nella società, focalizzandosi poi su alcuni aspetti della rappresentazione delle ‘donne moderne’ nei mass media prima, durante e dopo la Grande Guerra. Le immagini diventano, in alcuni casi, un vero e proprio campo di battaglia ideologico, con accenti sempre più accesi nel primo dopoguerra e nel fascismo.
description: Modernità nelle Americhe
Filaments from the galaxy distribution and from the velocity field in the local universe
Creators: name: Libeskind, Noam I.
name: Tempel, Elmo
name: Hoffman, Yehuda
name: Tully, R. Brent
name: Courtois, Helene
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The cosmic web that characterizes the large-scale structure of the Universe can be quantified by a variety of methods. For example, large redshift surveys can be used in combination with point process algorithms to extract long curvilinear filaments in the galaxy distribution. Alternatively, given a full 3D reconstruction of the velocity field, kinematic techniques can be used to decompose the web into voids, sheets, filaments and knots. In this paper we look at how two such algorithms - the Bisous model and the velocity shear web - compare with each other in the local Universe (within 100 Mpc), finding good agreement. This is both remarkable and comforting, given that the two methods are radically different in ideology and applied to completely independent and different data sets. Unsurprisingly, the methods are in better agreement when applied to unbiased and complete data sets, like cosmological simulations, than when applied to observational samples. We conclude that more observational data is needed to improve on these methods, but that both methods are most likely properly tracing the underlying distribution of matter in the Universe.
description: 6 Pages, 2 figures, Submitted to MNRAS Letters
title:  Economia (e politica) del moderno. Una proposta di revisione dei rapporti tra Futurismo italiano e Modernismo brasiliano
Creators: name: Finazzi-Agrò ,  Ettore
Publisher: name: Roma TrE-Press
Year: 2016

description: L’intervento propone un’analisi delle relazioni fra il modernismo brasiliano e le avanguardie europee primo-novecentesche. Il saggio è dunque centrato sul riesame dei manifesti di F.T. Marinetti e di Oswald de Andrade, tendenti a definire lo spazio ‘economico’ del Moderno e la costruzione ‘politica’ di una cultura realmente nazionale. In particolare, verranno scandagliate somiglianze e differenze fra le due dimensioni geopolitiche, in relazione al rapporto tra passato e presente, arcaico e moderno, memoria e oblio, tradizione e innovazione. Il tempo diviene dimensione esperienziale e storica al tempo stesso, costringendo a ragionare sulle strutture relazionali e intersoggettive della modernità attraverso il filtro del linguaggio e della rappresentazione.
description: Modernità nelle Americhe
Modeling the surface temperature of Earth-like planets
Creators: name: Vladilo, G.
name: Silva, L.
name: Murante, G.
name: Filippi, L.
name: Provenzale, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We introduce a novel Earth-like planet surface temperature model (ESTM) for habitability studies based on the spatial-temporal distribution of planetary surface temperatures. The ESTM adopts a surface Energy Balance Model complemented by: radiative-convective atmospheric column calculations, a set of physically-based parameterizations of meridional transport, and descriptions of surface and cloud properties more refined than in standard EBMs. The parameterization is valid for rotating terrestrial planets with shallow atmospheres and moderate values of axis obliquity (epsilon >= 45^o). Comparison with a 3D model of atmospheric dynamics from the literature shows that the equator-to-pole temperature differences predicted by the two models agree within ~5K when the rotation rate, insolation, surface pressure and planet radius are varied in the intervals 0.5 <= Omega/Omega_o <= 2, 0.75 <= S/S_o <= 1.25, 0.3 <= p/(1 bar) <= 10, and 0.5 <= R/R_o <= 2, respectively. The ESTM has an extremely low computational cost and can be used when the planetary parameters are scarcely known (as for most exoplanets) and/or whenever many runs for different parameter configurations are needed. Model simulations of a test-case exoplanet (Kepler-62e) indicate that an uncertainty in surface pressure within the range expected for terrestrial planets may impact the mean temperature by ~60 K. Within the limits of validity of the ESTM, the impact of surface pressure is larger than that predicted by uncertainties in rotation rate, axis obliquity, and ocean fractions. We discuss the possibility of performing a statistical ranking of planetary habitability taking advantage of the flexibility of the ESTM.
description: 32 pages, 15 figures, 2 tables, ApJ accepted
Hydrogen activation and catalytic reduction using low-valent group 14 complexes
Creators: name: Turnell-Ritson, Roland
Publisher: name: Imperial College London
Year: 2020

description: Main group chemistry, and chemical catalysis using main group elements, has undergone a renaissance in the new millenium. Low-valent main group complexes have demonstrated reactivity once thought possible only for the transition metals (TM), and the advent of ‘frustrated Lewis pair’ (FLP) chemistry has enabled main group compounds to perform efficient catalysis, most notably catalytic hydrogenation. This thesis describes advancements that have been made by combining the TM-like nature of the low-valent group 14 elements with the concept of FLP chemistry. Chapter 1 provides an introduction to the history and study of catalysis, the structure, bonding and reactivity of low-valent group 14 compounds, and FLP chemistry. Chapter 2 explores the FLP-type oxidative addition of H2 to a stannylene, catalysed by Lewis bases. A comprehensive mechanistic understanding is developed from a host of experimental and computational techniques. The use of Sn(IV) hydrides as reducing agents is subsequently investigated, and found to be limited in potential. Chapter 3 investigates the scope of stannylenes and germylenes that can participate in the FLP-mediated H2 activation reaction. A second mechanism is identified, generating transient E(II) monohydrides which are found to be potent reductants for ketones. Chapter 4 applies the understanding gained from the previous chapters to catalysis, uncovering the first example of catalytic hydrogenation of an imine using a tetrylene. Amidotetrylenes are further investigated as hydroboration catalysts, and found to be highly active with strongly electron-withdrawing ligands. Chapter 5 describes the ligand development undertaken for improvement of the catalytic hydrogenation system. Whilst no improved system is ultimately discovered, this chapter outlines the likely direction of successful future work. Chapter 6 contains experimental details of all the syntheses and reactions performed. A summary of all numbered structures is included on pages 22-24, and repeated in Appendix E for ease of reference.
(3509) Elizabeth Beckett
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Congruence of patient- and clinician-reported toxicity in women receiving chemotherapy for early breast cancer
Creators: name: Reeder-Hayes, K.E.
name: Shachar, S.S.
name: Basch, E.
name: Speca, J.C.
name: Reinbolt, R.E.
name: Lee, J.T.
name: Chen, Y.T.
name: Park, J.H.
name: Jolly, T.A.
name: Wood, W.A.
name: Reeve, B.B.
name: Muss, H.B.
name: Dees, E.C.
name: Kimmick, G.G.
name: Karuturi, M.S.
name: Deal, A.M.
name: Nyrop, K.A.
name: Carey, L.A.
Publisher: name: John Wiley and Sons Inc.
Year: 2020

description: Background: The National Cancer Institute's Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events, collected alongside the clinician-reported Common Terminology Criteria for Adverse Events, enables comparisons of patient and clinician reports on treatment toxicity. Methods: In a multisite study of women receiving chemotherapy for early-stage breast cancer, symptom reports were collected on the same day from patients and their clinicians for 17 symptoms; their data were not shared with each other. The proportions of moderate, severe, or very severe patient-reported symptom severity were compared with the proportions of clinician-rated grade 2, 3, or 4 toxicity. Patient-clinician agreement was assessed via κ statistics. Chi-square tests investigated whether patient characteristics were associated with patient-clinician agreement. Results: Among 267 women, the median age was 58 years (range, 24-83 years), and 26% were nonwhite. There was moderate scoring agreement (κ = 0.413-0.570) for 53% of symptoms, fair agreement for 41% (κ = 0.220-0.378), and slight agreement for 6% (κ = 0.188). For example, patient-reported and clinician-rated percentages were 22% and 8% for severe or very severe fatigue, 41% and 46% for moderate fatigue, 32% and 39% for mild fatigue, and 6% and 7% for none. Clinician severity scores were lower for nonwhite patients in comparison with white patients for peripheral neuropathy, nausea, arthralgia, and dyspnea. Conclusions: Although clinician reporting of symptoms is common practice in oncology, there is suboptimal agreement with the gold standard of patient self-reporting. These data provide further evidence supporting the integration of patient-reported outcomes into oncological clinical research and clinical practice to improve monitoring of symptoms as well as timely interventions for symptoms.