title: Ð§Ð¸ÑÐ»ÐµÐ½Ð½Ð¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¿ÑÐ¾ÑÐµÑÑÐ° ÑÑÐ¾Ð¼Ð±Ð¾Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð² Ð¼Ð¸ÐºÑÐ¾ÑÐ»ÑÐ¸Ð´Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ðµ Â«Ð¾ÑÐ³Ð°Ð½-Ð½Ð°-ÑÐ¸Ð¿ÐµÂ» Ñ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸ÐµÐ¼ Ð¿Ð°ÐºÐµÑÐ¾Ð² LabView Ð¸ COMSOL MULTIPHYSICS
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Numerical modeling of thrombus formation in an organ-on-chip microfluidic system using LabView and COMSOL MULTIPHYSICS packages
Creators: name: Ð§ÐµÑÐ½Ð¸ÐºÐ¾Ð², ÐÐ»ÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐÑÑÐ¸ÑÐ»Ð¸ÑÐµÐ»ÑÐ½ÑÐµ Ð¼Ð°ÑÐ¸Ð½Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½ÑÐµ
Ð¾ÑÐ³Ð°Ð½-Ð½Ð°-ÑÐ¸Ð¿Ðµ
ÑÑÐ¾Ð¼Ð±Ð¾Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ðµ
Ð¼Ð¸ÐºÑÐ¾ÑÐ»ÑÐ¸Ð´Ð¸ÐºÐ°

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÐºÐ¾Ð½Ð²ÐµÐºÑÐ¸Ð²Ð½Ð¾-Ð´Ð¸ÑÑÑÐ·Ð¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð¼Ð°ÑÑÐ¾Ð¿ÐµÑÐµÐ½Ð¾ÑÐ° Ð¿ÑÐ¸ Ð¸Ð¼Ð¸ÑÐ°ÑÐ¸Ð¸ Ð¿ÑÐ¾ÑÐµÑÑÐ° ÑÑÐ¾Ð¼Ð±Ð¾Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð² Ð¼Ð¸ÐºÑÐ¾ÑÐ»ÑÐ¸Ð´Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ðµ Ð¾ÑÐ³Ð°Ð½-Ð½Ð°-ÑÐ¸Ð¿Ðµ. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: 1. ÐÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°ÑÑ Ð´Ð¾ÑÑÐ¸Ð¶ÐµÐ½Ð¸Ñ Ð¼Ð¸ÑÐ¾Ð²Ð¾Ð¹ Ð½Ð°ÑÐºÐ¸ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ Ð¼Ð¸ÐºÑÐ¾ÑÐ»ÑÐ¸Ð´Ð¸ÐºÐ¸ Ð¸ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ ÐµÑ Ðº Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð¶Ð¸Ð·Ð½ÐµÐ´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¾Ð³Ð¾ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼Ð°; 2. ÐÐ»Ñ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² ÐºÐ¾Ð½Ð²ÐµÐºÑÐ¸Ð²Ð½Ð¾-Ð´Ð¸ÑÑÑÐ·Ð¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð¼Ð°ÑÑÐ¾Ð¿ÐµÑÐµÐ½Ð¾ÑÐ° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°ÑÑ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÑÑ Ð¼Ð¾Ð´ÐµÐ»Ñ ÑÑÐ¾Ð¼Ð±Ð¾Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð² Ð¼Ð¸ÐºÑÐ¾ÑÐ»ÑÐ¸Ð´Ð½Ð¾Ð¼ ÐºÐ°Ð½Ð°Ð»Ðµ; 3.ÐÑÐµÐ½Ð¸ÑÑ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ Ð¿ÑÐ¾ÑÐµÑÑÐ° ÑÐ¾ÑÑÐ° ÑÑÐ¾Ð¼Ð±Ð°; 3. ÐÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°ÑÑ Ð³Ð¸Ð´ÑÐ¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ Ð¿Ð¾ÑÐ¾ÐºÐ° ÐºÑÐ¾Ð²Ð¸; Ð Ð°Ð±Ð¾ÑÐ° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð½Ð° Ð±Ð°Ð·Ðµ ÐÐÐ Ð ÐÐ, Ð³Ð´Ðµ Ð¿ÑÐ¸ÑÑÑÑÑÐ²ÑÐµÑ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð°ÐºÐµÑÐ° COMSOL Multiphysics, ÑÑÐµÐ±ÑÑÑÐµÐ³Ð¾ Ð»Ð¸ÑÐµÐ½Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÑÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ Ð²ÑÑÐ¸ÑÐ»Ð¸ÑÐµÐ»ÑÐ½ÑÑ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐµÐ¹. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð±ÑÐ»Ð° Ð¿Ð¾Ð»ÑÑÐµÐ½Ð° Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ°Ñ Ð¼Ð¾Ð´ÐµÐ»Ñ LabView, Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑÐ°Ñ Ð¸Ð·Ð¼ÐµÐ½ÑÑÑ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ ÐºÑÐ¾Ð²Ð¸, ÑÐ°ÐºÐ¸Ð¼ Ð¾Ð±ÑÐ°Ð·Ð¾Ð¼ Ð½Ð°Ð±Ð»ÑÐ´Ð°Ñ Ð·Ð° Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¾Ð¹ ÑÑÐ¾Ð¼Ð±Ð¾Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð² ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ ÑÑÐ»Ð¾Ð²Ð¸ÑÑ.
description: This work is devoted to the study of convective-diffusion mass transfer during imitation of the process of thrombus formation in the microfluidic organ-on-a-chip system. The tasks that were solved in the course of the study: 1. Analyze the achievements of world science in the field of microfluidics and its application to modeling the processes of vital activity of the human body; 2. For the methods of convective-diffusion mass transfer, develop a mathemati-cal model of thrombus formation in the microfluidic channel; 3. To estimate the parameters of the process of thrombus growth; 3. Analyze the hydrodynamic parameters of the blood flow; The work was carried out on the basis of the IAI RAS, where it is possible to use the COMSOL Multiphysics package, which requires licensing and significant compu-ting power. As a result, a mathematical model LabView was obtained, which makes it possi-ble to change the blood parameters, thus observing the dynamics of thrombus for-mation in various conditions.