cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Gruppenarbeit – Viel mehr als nur „Brainstorming“ ...
Creators: name: Baumann, Martin
name: Ritter, Andreas
name: Engelmann, Ulrich
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 8-20    Lernziele: Wer sich beim Titel dieses Workshops mit Schrecken an so manches Seminar im Studium oder aber an das eine oder andere Team-Meeting der Projektgruppe erinnert fühlt, in der Gruppenarbeit auf „Mind-Maps“ reduziert und im Rahmen dessen eine Tafel[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Konsensbildung: Die Delphi-Methode als hilfreiches Werkzeug
Creators: name: Rotgans, Jerome
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 8-24    Lernziele: Die Delphi-Methode ist eine strukturierte Befragung von Experten, die ursprünglich in den sechziger Jahren in den USA zur Abstimmung von Experten bei schwierigen militärischen Entscheidungen entwickelt wurde. Heute wird sie weltweit in vielen verschiedenen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Christian Podzuweit, Trojanische Gefäßformen der Frühbronzezeit in Anatolien, der Ägäis und angrenzenden Gebieten
Creators: name: Hiller, Stefan
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Christian Podzuweit, Trojanische Gefäßformen der Frühbronzezeit in Anatolien, der Ägäis und angrenzenden Gebieten. Ein Beitrag zur vergleichenden Stratigraphie. Verlag Philipp von Zabern, Mainz 1979. 249 Seiten, 33 Tafeln, 27 Beilagen.
description: Bonner Jahrbücher, Bd. 182.1982: Bonner Jahrbücher
Shapes of hydrophobic thick membranes
Creators: name: Hoang, Trinh X.
name: Banavar, Jayanth R.
name: Maritan, Amos
Publisher: name: arXiv
Year: 2012
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biomolecules (q-bio.BM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We introduce and study the behavior of a tethered membrane of non-zero thickness embedded in three dimensions subject to an effective self-attraction induced by hydrophobicity arising from the tendency to minimize the area exposed to a solvent. The phase behavior and the nature of the folded conformations are found to be quite distinct in the small and large solvent size regimes. We demonstrate spontaneous symmetry-breaking with the membrane folding along a preferential axis, when the solvent molecules are small compared to the membrane thickness. For large solvent molecule size, a local crinkling mechanism effectively shields the membrane from the solvent, even in relatively flat conformations. We discuss the binding/unbinding transition of a membrane to a wall that serves to shield the membrane from the solvent.
description: 7 pages, 5 figures, to appear in EPL
title: Multiple-Choice-Fragen rasch und einfach erstellen
Creators: name: Bernhardt-Melischnig, Johannes
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Anzahl der Teilnehmer: 3-15    Lernziele: Die Teilnehmer und Teilnehmerinnen sollen am Ende des Workshops in der Lage sein, hochwertige Multiple-Choice-Prüfungsfragen im Fachbereich der Humanmedizin zu erstellen. Folgende Themenbereiche werden behandelt: Prüfungsinhalte bzw. Umgang mit Lernzielkatalogen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Hans Hingst, Jevenstedt. Ein Urnenfriedhof der älteren vorrömischen Eisenzeit im Kreise Rendsburg-Eckernförde, Holstein
Creators: name: Jacob-Friesen, Gernot
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Hans Hingst, Jevenstedt. Ein Urnenfriedhof der älteren vorrömischen Eisenzeit im Kreise Rendsburg-Eckernförde, Holstein. Offa-Bücher 27. Karl-Wachholtz-Verlag, Neumünster 1974. 121 Seiten, 10 Abbildungen, 4 Farbtafeln, 89 Tafeln, 21 Detailkarten sowie ein Plan des Gräberfeldes.
description: Bonner Jahrbücher, Bd. 182.1982: Bonner Jahrbücher
Kerberos Authentication in Wireless Sensor Networks
Creators: name: Siddique, Qasim
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: We proposed an authentication mechanism in the wireless sensor network. Sensor network uses the Kerberos authentication scheme for the authentication of bases station in the network. Kerberos provides a centralized authentication server whose function is to authenticate user by providing him the ticket to grant request to the base station. In this paper we have provided architecture for the authentication of base station in the wireless sensor network based on the Kerberos server authentication scheme.
description: 14 pages
Gerd Rupprecht, Untersuchungen zum Dekurionenstand in den nordwestlichen Provinzen des römischen Reiches
Creators: name: Wolff, Hartmut
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Gerd Rupprecht, Untersuchungen zum Dekurionenstand in den nordwestlichen Provinzen des römischen Reiches. Frankfurter Althistorische Studien 8. Verlag Michael Laßleben, Kalimünz 1975. 241 Seiten, 7 Karten.
description: Bonner Jahrbücher, Bd. 182.1982: Bonner Jahrbücher
Structure-based identification of natural compound inhibitor against M. tuberculosis thioredoxin reductase: insight from molecular docking and dynamics simulation
Creators: name: Lata, Surabhi
name: Akif, Mohd.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Antioxidant systems of M. tuberculosis (Mtb) play an important role in providing resistance in the hostile environment of mononuclear phagocytes. Thioredoxin system is a known antioxidant system that consists of three copies of thioredoxins (Trxs) and a single copy of thioredoxin reductase (TrxR). TrxR has been validated as an essential gene known to be involved in the reduction of peroxides, dinitrobenzenes and hydroperoxides, and is crucial in maintaining the survival of Mtb in macrophages. Recently, it has been demonstrated to be a druggable target. In this study, molecular docking was applied to screen more than 20,000 natural compounds from the Traditional Chinese Medicine database. Theoretical calculation of ΔGbinding by the Molecular Mechanics Poisson-Boltzmann Surface Area (MM-PBSA) methods indicated two top-hit compounds that bind with a high affinity to the allosteric site, consisting of a hinge region, of TrxR. Further, stability and binding analysis of both compounds were carried out with molecular dynamics simulation. An analysis of conformational variation by principal component analysis (PCA) and protein contact network (PCN) uncovered the conformational changes in the compound-bound forms of protein. The NADPH domain formed many new interactions with the FAD domain in the compound-bound form, signifying that the binding may render an effect on the protein structure and function. Our results suggest that these two compounds could potentially be used for structure-based lead inhibitors against TrxR. The inhibitor selected as lead compound will be used further as a scaffold to optimize as novel anti-tuberculosis therapeutic. Communicated by Ramaswamy H. Sarma
Susanne Zabehlicky-Scheffenegger, Burnum 1. Erster Bericht über die Kleinfunde der Grabungen 1973 und 1974 auf dem Forum
Creators: name: Haalebos, Jan Kees
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Susanne Zabehlicky-Scheffenegger, Burnum 1. Erster Bericht über die Kleinfunde der Grabungen 1973 und 1974 auf dem Forum. Mit einem Beitrag von M. Kandier. Österreichische Akademie der Wissenschaften, Schriften der Balkankommission, antiquarische Abteilung, 14. Verlag der österreichischen Akademie der Wissenschaften, Wien 1979. 52 Seiten, 22 Tafeln, 1 Karte.
description: Bonner Jahrbücher, Bd. 182.1982: Bonner Jahrbücher
A Stellar Dynamical Mass Measurement of the Black Hole in NGC 3998 from Keck Adaptive Optics Observations
Creators: name: Walsh, Jonelle L.
name: Bosch, Remco C. E. van den
name: Barth, Aaron J.
name: Sarzi, Marc
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a new stellar dynamical mass measurement of the black hole in the nearby, S0 galaxy NGC 3998. By combining laser guide star adaptive optics observations obtained with the OH-Suppressing Infrared Imaging Spectrograph on the Keck II telescope with long-slit spectroscopy from the Hubble Space Telescope and the Keck I telescope, we map out the stellar kinematics on both small spatial scales, well within the black hole sphere of influence, and on large scales. We find that the galaxy is rapidly rotating and exhibits a sharp central peak in the velocity dispersion. Using the kinematics and the stellar luminosity density derived from imaging observations, we construct three-integral, orbit-based, triaxial stellar dynamical models. We find the black hole has a mass of M_BH = (8.1_{-1.9}^{+2.0}) x 10^8 M_sun, with an I-band stellar mass-to-light ratio of M/L = 5.0_{-0.4}^{+0.3} M_sun/L_sun (3-sigma uncertainties), and that the intrinsic shape of the galaxy is very round, but oblate. With the work presented here, NGC 3998 is now one of a very small number of galaxies for which both stellar and gas dynamical modeling have been used to measure the mass of the black hole. The stellar dynamical mass is nearly a factor of four larger than the previous gas dynamical black hole mass measurement. Given that this cross-check has so far only been attempted on a few galaxies with mixed results, carrying out similar studies in other objects is essential for quantifying the magnitude and distribution of the cosmic scatter in the black hole mass - host galaxy relations.
description: 19 pages, 15 figures, accepted for publication in ApJ
Identification of potential natural inhibitors of SARS-CoV2 main protease by molecular docking and simulation studies
Creators: name: Gupta, Sanjay
name: Singh, Atul Kumar
name: Kushwaha, Prem Prakash
name: Prajapati, Kumari Sunita
name: Shuaib, Mohd
name: Senapati, Sabyasachi
name: Kumar, Shashank
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Coronaviruses are contagious pathogens primarily responsible for respiratory and intestinal infections. Research efforts to develop antiviral agents against coronavirus demonstrated the main protease (Mpro) protein may represent effective drug target. X-ray crystallographic structure of the SARS-CoV2 Mpro protein demonstrated the significance of Glu166, Cys141, and His41 residues involved in protein dimerization and its catalytic function. We performed in silico screening of compounds from Curcuma longa L. (Zingiberaceae family) against Mpro protein inhibition. Employing a combination of molecular docking, scoring functions, and molecular dynamics simulations, 267 compounds were screened by docking on Mpro crystallographic structure. Docking score and interaction profile analysis exhibited strong binding on the Mpro catalytic domain with compounds C1 (1E,6E)-1,2,6,7-tetrahydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione) and C2 (4Z,6E)‐1,5‐dihydroxy‐1,7‐bis(4‐hydroxyphenyl)hepta‐4,6‐dien‐3‐one as lead agents. Compound C1 and C2 showed minimum binding score (–9.08 and –8.07 kcal/mole) against Mpro protein in comparison to shikonin and lopinavir (≈ −5.4 kcal/mole) a standard Mpro inhibitor. Furthermore, principal component analysis, free energy landscape and protein-ligand energy calculation studies revealed that these two compounds strongly bind to the catalytic core of the Mpro protein with higher efficacy than lopinavir, a standard antiretroviral of the protease inhibitor class. Taken together, this structure based optimization has provided lead on two natural Mpro inhibitors for further testing and development as therapeutics against human coronavirus. Communicated by Ramaswamy H. Sarma
Postpartum contraceptive counseling: starting prenatally to better guide patients’ decision making
Creators: name: Delao, Alejandra
Publisher: name: No Publisher Supplied
Year: 2022

description: Purpose of Project: The purpose of this project was to evaluate the effectiveness of provider-initiated prenatal contraceptive counseling and its impact on selection and documentation of a contraceptive method. The distribution of patient information material (PIM) was also evaluated. Methodology: A retrospective chart review was done to assess documentation of contraceptive counseling in the second or third trimesters, or during both times from February to April 2022. Results: A total of 90 charts were reviewed. The average age of women in the sample was 35, mostly married, and of gravida one and parity zero. More women received prenatal counseling in the third trimester than in the second, since more women presented in their third trimester at time of project initiation. However, the most significant impact was seen by second trimester counseling, where 91.7% of women selected a method of birth control, ?? (1, N = 90) = 36.402, p < .001. The distribution of PIM in the patient’s preferred language also produced statistically significant results in relation to the selection of a contraceptive method. The most frequently chosen method of birth control was the pill. Implications for Practice: Contraceptive counseling offered prenatally has the potential to assist women in the selection of a birth control method to use after giving birth. Providing health-related material tailored to patient’s literacy needs may have an impact on the ability to make informed decisions about one’s wellbeing. Both aspects play a crucial role in reducing the rate of unplanned pregnancies and optimizing interpregnancy intervals, thus allowing for the evolution of healthy pregnancies.
IVOA Recommendation: The UCD1+ controlled vocabulary Version 1.23
Creators: name: Martinez, Andrea Preite
name: Derriere, Sebastien
name: Delmotte, Nausicaa
name: Gray, Norman
name: Mann, Robert
name: McDowell, Jonathan
name: Glynn, Thomas Mc
name: Ochsenbein, Francois
name: Osuna, Pedro
name: Rixon, Guy
name: Williams, Roy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: This document describes the list of controlled terms used to build the Unified Content Descriptors, Version 1+ (UCD1+). The document describing the UCD1+ can be found at the URL: http://www.ivoa.net/Documents/latest/UCD.html. This document reviews the structure of the UCD1+ and presents the current vocabulary.
Why isn't the solar constant a constant?
Creators: name: Li, K. J.
name: Feng, W.
name: Xu, J. C.
name: Gao, P. X.
name: Yang, L. H.
name: Liang, H. F.
name: Zhan, L. S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In order to probe the mechanism of variations of the Solar Constant on the inter-solar-cycle scale, total solar irradiance (TSI, the so-called Solar Constant) in the time interval of 7 November 1978 to 20 September 2010 is decomposed into three components through the empirical mode decomposition and time-frequency analyses. The first component is the rotation signal, counting up to 42.31% of the total variation of TSI, which is understood to be mainly caused by large magnetic structures, including sunspot groups. The second is an annual-variation signal, counting up to 15.17% of the total variation, the origin of which is not known at this point in time. Finally, the third is the inter-solar-cycle signal, counting up to 42.52%, which are inferred to be caused by the network magnetic elements in quiet regions, whose magnetic flux ranges from $(4.27-38.01)\times10^{19}$ Mx.
description: to appear in ApJ
Virtual screening-driven drug discovery of SARS-CoV2 enzyme inhibitors targeting viral attachment, replication, post-translational modification and host immunity evasion infection mechanisms
Creators: name: Quimque, Mark Tristan J.
name: Notarte, Kin Israel R.
name: Fernandez, Rey Arturo T.
name: Mendoza, Mark Andrew O.
name: Liman, Rhenz Alfred D.
name: Lim, Justin Allen K.
name: Pilapil, Luis Agustin E.
name: Ong, Jehiel Karsten H.
name: Pastrana, Adriel M.
name: Khan, Abbas
name: Wei, Dong-Qing
name: Macabeo, Allan Patrick G.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: The novel coronavirus SARS-CoV2, the causative agent of the pandemic disease COVID-19, emerged in December 2019 forcing lockdown of communities in many countries. The absence of specific drugs and vaccines, the rapid transmission of the virus, and the increasing number of deaths worldwide necessitated the discovery of new substances for anti-COVID-19 drug development. With the aid of bioinformatics and computational modelling, ninety seven antiviral secondary metabolites from fungi were docked onto five SARS-CoV2 enzymes involved in viral attachment, replication, post-translational modification, and host immunity evasion infection mechanisms followed by molecular dynamics simulation and in silico ADMET prediction (absorption, distribution, metabolism, excretion and toxicity) of the hit compounds. Thus, three fumiquinazoline alkaloids scedapin C (15), quinadoline B (19) and norquinadoline A (20), the polyketide isochaetochromin D1 (8), and the terpenoid 11a-dehydroxyisoterreulactone A (11) exhibited high binding affinities on the target proteins, papain-like protease (PLpro), chymotrypsin-like protease (3CLpro), RNA-directed RNA polymerase (RdRp), non-structural protein 15 (nsp15), and the spike binding domain to GRP78. Molecular dynamics simulation was performed to optimize the interaction and investigate the stability of the top-scoring ligands in complex with the five target proteins. All tested complexes were found to have dynamic stability. Of the five top-scoring metabolites, quinadoline B (19) was predicted to confer favorable ADMET values, high gastrointestinal absorptive probability and poor blood-brain barrier crossing capacities. Communicated by Ramaswamy H. Sarma
Magnetic topology of a naked sunspot: Is it really naked?
Creators: name: Dalda, A. Sainz
name: Dominguez, S. Vargas
name: Tarbell, T. D.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The high spatial, temporal and spectral resolution achieved by Hinode instruments give much better understanding of the behavior of some elusive solar features, such as pores and naked sunspots. Their fast evolution and, in some cases, their small sizes have made their study difficult. The moving magnetic features, despite being more dynamic structures, have been studied during the last 40 years. They have been always associated with sunspots, especially with the penumbra. However, a recent observation of a naked sunspot (one with no penumbra) has shown MMF activity. The authors of this reported observation expressed their reservations about the explanation given to the bipolar MMF activity as an extension of the penumbral filaments into the moat. How can this type of MMFs exist when a penumbra does not? In this paper, we study the full magnetic and (horizontal) velocity topology of the same naked sunspot, showing how the existence of a magnetic field topology similar to that observed in sunspots can explain these MMFs, even when the intensity map of the naked sunspot does not show a penumbra.
description: 6 pages, 2 figures
title: Оценка точности определения таксационных показателей
Creators: name: Столярова, Владислава
name: Лукашик, Евгений
name: Пермяков, Анатолий
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2021

description: Одним из ключевых вопросов при устройстве и инвентаризации лесов является точность результатов лесоустроительных работ. При дешифрировании материалов дистанционного зондирования к проблемам точности добавляется еще и достоверность распознавания земель различных категорий по материалам
дистанционного зондирования. Достоверность результатов дешифрирования является определяющей при проработке данной темы, так как определение точности теряет смысл для ошибочно определенных категорий земель. Повышение достоверности и точности определения таксационных показателей по материалам дистанционного зондирования с использованием ГИС-технологий соответствует концепции развития
российского лесного хозяйства и лесоустройства. Новые экономические условия диктуют необходимость непрерывной оценки всех лесов, независимо от их ведомственной принадлежности. Важнейшим условием успешной реализации данной программы является высокая достоверность и достаточная точность результатов
дешифрирования материалов дистанционного зондирования.
Helmut J. Kroll, Kastanas. Ausgrabungen in einem Siedlungshügel der Bronze- und Eisenzeit Makedoniens 1975-1979. Die Pflanzenfunde
Creators: name: Knörzer, Karl-Heinz
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Helmut J. Kroll, Kastanas. Ausgrabungen in einem Siedlungshügel der Bronze- und Eisenzeit Makedoniens 1975-1979. Die Pflanzenfunde. Prähistorische Archäologie in Südosteuropa 2. Verlag Volker Spiess, Berlin 1983. 176 Seiten, 31 gezeichnete Abbildungen, 53 Tabellen z. T. auf 6 Faltblattbeilagen. Griechische Zusammenfassung.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher
Biological and molecular modeling studies on some transition metal(II) complexes of a Quinoxaline based ONO donor bishydrazone ligand
Creators: name: Johnson, Jijo
name: Dhanaraj, Chellaian Justin
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: In this report, synthesis, characterization, biological and molecular modeling studies of an ONO donor tridentate bishydrazone ligand, 3-[N'-(2-Hydroxy-3-methoxy-benzylidene)-hydrazino]-1H-quinoxalin-2-one (HHQ) and its 1:1 mononuclear Co(II) complex (HHQ-1), Ni(II) complex (HHQ-2), Cu(II) complex (HHQ-3) and Zn(II) complex (HHQ-4) have been conferred. Octahedral geometries were assigned to HHQ-1, HHQ-2 and HHQ-4 and distorted octahedral geometry for HHQ-3. The lattice parameters, morphology and electrochemical behavior of the compounds were studied by powder XRD, SEM and cyclic voltammetry analyses respectively. The antimicrobial assays were carried out against the bacterial (S. aureus, E. coli and P. aeruginosa) and fungal (A. flavus, A. niger and C. albicans) strains. Furthermore, the DNA binding, cleaving and SOD activities of HHQ and its metal(II) complexes were discussed. The structures of HHQ and its derivatives were optimized by DFT techniques. Using molecular docking the molecular interaction dynamics amongst the DNA and SOD with HHQ and its metal(II) complexes were recognized.
Maximum likelihood fitting of X-ray power density spectra: Application to high-frequency quasi-periodic oscillations from the neutron star X-ray binary 4U1608-522
Creators: name: Barret, Didier
name: Vaughan, Simon
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: High frequency quasi-periodic oscillations (QPOs) from weakly magnetized neutron stars display rapid frequency variability and high coherence with quality factors up to at least 200 at frequencies around 850 Hz. Their parameters have been estimated so far from standard min(chi2) fitting techniques, after combining a large number of Power Density Spectra (PDS), as to have the powers normally distributed. Accounting for the statistical properties of PDS, we apply a maximum likelihood method to derive the QPO parameters in the non Gaussian regime. The method presented is general, easy to implement and can be applied to fitting individual PDS, several PDS simultaneously or their average, and is obviously not specific to the analysis of kHz QPO data. It applies to the analysis of any PDS optimized in frequency resolution and for low frequency variability or PDS containing features whose parameters vary on short timescales, as is the case for kHz QPOs. It is equivalent to the standard chi^2 minimization fitting when the number of PDS fitted is large. The accuracy, reliability and superiority of the method is demonstrated with simulations of synthetic PDS. We show that the maximum likelihood estimates of the QPO parameters are asymptotically unbiased, and have negligible bias when the QPO is reasonably well detected. By contrast, we show that the standard min(chi2) fitting method gives biased parameters with larger uncertainties. The maximum likelihood fitting method is applied to a subset of archival Rossi X-ray Timing Explorer (RXTE) data of the neutron star X-ray binary 4U1608-522. We show that the kHz QPO parameters can be measured on 8 second timescales and that the time evolution of the frequency is consistent with a random walk. This enables us to estimate the intrinsic quality factor of the QPO to be around 260, whereas previous analysis indicated a maximum value around 200 (abridged).
description: 24 pages, 8 figures, Accepted for publication in the Astrophysical Journal
Energy of Stable Half-Quantum Vortex in Equal-Spin-Pairing
Creators: name: Haghdani, Shokouh
name: Shahzamanian, Mohammad Ali
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In the triplet equal-spin-pairing states of both 3He-A phase and Sr2RuO4 superconductor, existence of Half-Quantum Vortices HQVs are possible. The vortices carry half-integer multiples of magnetic quantum flux (hc/2e). To obtain equilibrium condition for such systems, one has to take into account not only weak interaction energy but also effects of Landau Fermi liquid. Our method is based on the explanation of the HQV in terms of a BCS-like wave function with a spin-dependent boots. We have considered l=2 order effects of the Landau Fermi liquid. We have shown that the effects of Landau Fermi liquid interaction with l=2 are negligible. In stable HQV, an effective Zeeman field exists. In the thermodynamic stability state, the effective Zeeman field produces a non-zero spin polarization in addition to the polarization of external magnetic field.
Phase Transition and Anisotropic Deformations of Neutron Star Matter
Creators: name: Nelmes, S. G.
name: Piette, B. M. A. G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The Skyrme model is a low energy, effective field theory for QCD which when coupled to a gravitational field provides an ideal semi-classical model to describe neutron stars. We use the Skyrme crystal solution composed of a lattice of $α$-like particles as a building block to construct minimum energy neutron star configurations, allowing the crystal to be strained anisotropically. We find that below 1.49 solar masses the stars' crystal deforms isotropically and that above this critical mass, it undergoes anisotropic strain. We then find that the maximum mass allowed for a neutron star is 1.90 solar masses, in close agreement with a recent observation of the most massive neutron star yet found. The radii of the computed solutions also match the experimentally estimated values of approximately 10km.
description: 28 pages, 11 figures, and 2 tables
Computational investigation of potential inhibitors of novel coronavirus 2019 through structure-based virtual screening, molecular dynamics and density functional theory studies
Creators: name: Mishra, Shashank Shekhar
name: Ranjan, Shashi
name: Sharma, Chandra Shekhar
name: Singh, Hemendra Pratap
name: Kalra, Sourav
name: Kumar, Neeraj
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Despite the intensive research efforts towards antiviral drug against COVID-19, no potential drug or vaccines has not yet discovered. Initially, the binding site of COVID-19 main protease was predicted which located between regions 2 and 3. Structure-based virtual screening was performed through a hierarchal mode of elimination technique after generating a grid box. This led to the identification of five top hit molecules that were selected on the basis of docking score and visualization of non-bonding interactions. The docking results revealed that the hydrogen bonding and hydrophobic interactions are the major contributing factors in the stabilization of complexes. The docking scores were found between −7.524 and −6.711 kcal/mol indicating strong ligand-protein interactions. Amino acid residues Phe140, Leu141, Gly143, Asn142, Thr26, Glu166 and Thr190 (hydrogen bonding interactions) and Phe140, Cys145, Cys44, Met49, Leu167, Pro168, Met165, Val42, Leu27 and Ala191 (hydrophobic interactions) formed the binding pocket of COVID-19 main protease. From identified hits, ZINC13144609 and ZINC01581128 were selected for atomistic MD simulation and density functional theory calculations. MD simulation results confirm that the protein interacting with both hit molecules is stabilized in the chosen POPC lipid bilayer membrane. The presence of lowest unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO) in the hydrophobic region of the hit molecules leads to favorable ligand-protein contacts. The calculated pharmacokinetic descriptors were found to be in their acceptable range and therefore confirming their drug-like properties. Hence, the present investigation can serve as the basis for designing and developing COVID-19 inhibitors. Communicated by Ramaswamy H. Sarma
Development of the Schrodinger equation for attosecond laser pulse interaction with Planck gas
Creators: name: Kozlowski, M.
name: Marciak-Kozlowska, J.
name: Pilsudski, Josef
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: The creation of the new particles by the interaction of the ultrarelativistic ions,from Large Hadron Collider(LHC), and attosecond laser pulse open new possibilities for laser physicists community .In this paper we propose the hyperbolic Schrödinger equation (HSE) for gas of the "classical" particles "i.e. particles with mass= Planck mass We discuss the inclusion of the gravity to the HSE The solution of the HSE for a particle in a box is obtained. It is shown that for particles with m greater than Mp the energy spectrum is independent of the mass of particle. Key words: attosecond laser pulses, Schrodinger equation, Planck particles, thermal processes
description: 11pgs
Karl Christ, Römische Geschichte und Wissenschaftsgeschichte 2. Geschichte und Geschichtsschreibung der römischen Kaiserzeit
Creators: name: Schrömbges, Paul
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Karl Christ, Römische Geschichte und Wissenschaftsgeschichte 2. Geschichte und Geschichtsschreibung der römischen Kaiserzeit. Wissenschaftliche Buchgesellschaft, Darmstadt 1983. VII und 287 Seiten.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher
Synthesis, Molecular modelling, FT-IR, Raman and NMR characterization, Molecular Docking and ADMET Study of New Nickel(II) complex with an N4-tetradentate thiosemicarbazone
Creators: name: Eglence-Bakir, Songul
name: Celik, Sefa
name: Sahin, Musa
name: Ozel, Aysen E.
name: Akyuz, Sevim
name: Ulkuseven, Bahri
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: A new nickel(II) complex was synthesized by using S-propyl-thiosemicarbazide and 2-amino-3,5-dibromobenzaldehyde. The complex, obtained by the template effect of nickel ions, was structurally analysed by experimental and theoretical vibrational spectroscopy, NMR and density functional theory (DFT) calculations. By using DFT/B3LYP method with 6-311++G(d, p) basis set, the most stable molecular structure of the title molecule was calculated. The fundamental vibrational wavenumbers, IR and Raman intensities for the optimized structure of the molecule under investigation were determined and compared with the experimental vibrational spectra. The vibrational assignment was achieved using the calculated potential energy distributions of the vibrational modes. Moreover, the molecular electrostatic potential (MEP), the highest occupied molecular orbital (HOMO) and the lowest occupied molecular orbital (LUMO) energies were calculated, Molecular docking of the molecule was carried out against DNA in order to identify the potential inhibitory action of the title compound. The findings suggested that the aforementioned compound has a strong binding affinity to interact with DNA residues DT8, DC9, DG12, DG16, DA17, and DA18 through the intermolecular hydrogen bonds. Also the performed in silico ADMET analysis was the prediction of the synthesized molecule's pharmacokinetic and toxicity profile expressing good oral drug like actions and non-toxic nature. The complex has been shown to have the possibility to become a model molecule for drug development processes.
Manfred Clauss, Der magister officiorum in der Spätantike (4.-6. Jahrhundert). Das Amt und sein Einfluß auf die kaiserliche Politik
Creators: name: Horstkotte, H.
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Manfred Clauss, Der magister officiorum in der Spätantike (4.-6. Jahrhundert). Das Amt und sein Einfluß auf die kaiserliche Politik. Vestigia 32. Verlag C. H. Beck, München 1980. VII und 252 Seiten.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher
IVOA Recommendation: Maintenance of the list of UCD words Version 1.20
Creators: name: Delmotte, Nausicaa
name: Derriere, Sebastien
name: Gray, Norman
name: Mann, Robert
name: McDowell, Jonathan
name: Glynn, Thomas Mc
name: Ochsenbein, Francois
name: Osuna, Pedro
name: Martinez, Andrea Preite
name: Rixon, Guy
name: Williams, Roy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: According to what is stated in the IVOA Recommendation "An IVOA standard for Unified Content Descriptors", a procedural document should be created in order to maintain (add, change, suppress words) the standard list of UCD1+ words "The UCD1+ Controlled Vocabulary". This document describes the procedure to maintain the standard list of UCD1+ words.
Comment on `Controversy concerning the definition of quark and gluon angular momentum' by Elliot Leader (arXiv:1101.5956, PRD 83, 096012 (2011))
Creators: name: Lin, Huey-Wen
name: Liu, Keh-Fei
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: It is argued by the author that the canonical form of the quark energy-momentum tensor with a partial derivative instead of the covariant derivative is the correct definition for the quark momentum and angular momentum fraction of the nucleon in covariant quantization. Although it is not manifestly gauge invariant, its matrix elements in the nucleon will be non-vanishing and are gauge invariant. We test this idea in the path-integral quantization by calculating correlation functions on the lattice with a gauge-invariant nucleon interpolation field and replacing the gauge link in the quark lattice momentum operator with unity, which corresponds to the partial derivative in the continuum. We find that the ratios of three-point to two-point functions are zero within errors for both the u and d quarks, contrary to the case without setting the gauge links to unity.
description: 2 pages, 2 figures
Gerhard Zimmer, Römische Berufsdarstellungen
Creators: name: Kneißl, Peter
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Gerhard Zimmer, Römische Berufsdarstellungen. Archäologische Forschungen 12. Gebr. Mann Verlag, Berlin 1982. 254 Seiten, 209 Katalogabbildungen.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher
P. Crummy, Colchester Archaeological Report 3. Excavations at Lion Walk, Baikerne Lane, and Middleborough, Colchester, Essex
Creators: name: Esmonde Cleary, A. Simon
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: P. Crummy, Colchester Archaeological Report 3. Excavations at Lion Walk, Baikerne Lane, and Middleborough, Colchester, Essex. Colchester Archaeological Trust Ltd., Colchester 1984. xi and 224 pages, 204 figures, 6 outsize plans, 5 microfiche sheets.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher
R. G. Collingwood and R. P. Wright, The Roman Inscriptions of Britain 1. Inscriptions on Stone
Creators: name: Galsterer, Brigitte
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: R. G. Collingwood and R. P. Wright, The Roman Inscriptions of Britain 1. Inscriptions on Stone. Epigraphic Indexes, compiled by Roger Goodburn and Helen Waugh. Alan Sutton Publishing, Gloucester 1983. XVI und 109 Seiten.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher
Inhibition of fibrillation of human γd-crystallin by a flavonoid morin
Creators: name: Rana, Shiwani
name: Ghosh, Kalyan Sundar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Marine Biology

description: To inhibit the formation of amyloid fibrils by human γd-crystallin (HGD), a series of four flavonoids (quercertin, rutin, morin and hesperetin) was tested. Only morin had demonstrated significant inhibition of HGD fibrillation. Results from fluorimetric assay techniques (using thioflavin T and ANS), FTIR, circular dichroism and microscopic imaging (fluorescence microscopy and transmission electron microscopy) confirmed HGD fibrillation inhibition by morin. HGD–morin complex formation at ground state resulted tryptophan fluorescence quenching through static mechanism, which was also confirmed by determining the excited-state life time of HGD tryptophan residues. Förster resonance energy transfer occurs from HGD to morin. Synchronous, three-dimensional fluorescence, FTIR and circular dichroism results suggest that major changes in HGD conformation did not occur on binding with morin. The interactions between HGD and morin involve hydrogen bonding and/or van der Waals forces. Docking predictions also support experimental results. Communicated by Ramaswamy H. Sarma
Lothar Waldmüller, Die ersten Begegnungen der Slawen mit dem Christentum und den christlichen Völkern vom 6.-8. Jahrh. Die Slawen zwischen Byzanz und dem Abendland
Creators: name: Wirth, Gerhard
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Lothar Waldmüller, Die ersten Begegnungen der Slawen mit dem Christentum und den christlichen Völkern vom 6.-8. Jahrh. Die Slawen zwischen Byzanz und dem Abendland. Verlag A. Hakkert, Amsterdam 1976. XIV und 712 Seiten.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher
Study of single-lobed circular polarization profiles in the quiet Sun
Creators: name: Dalda, A. Sainz
name: Martinez-Sykora, J.
name: Rubio, L. Bellot
name: Title, A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The existence of asymmetries in the circular polarization (Stokes V) profiles emerging from the solar photosphere is known since the 1970s. These profiles require the presence of a velocity gradient along the line of sight, possibly associated with gradients of magnetic field strength, inclination and/or azimuth. We have focused our study on the Stokes V profiles showing extreme asymmetry in the from of only one lobe. Using Hinode spectropolarimetric measurements we have performed a statistical study of the properties of these profiles in the quiet sun. We show their spatial distribution, their main physical properties, how they are related with several physical observables and their behavior with respect to their position on the solar disk. The single lobed Stokes V profiles occupy roughly 2% of the solar surface. For the first time, we have observed their temporal evolution and have retrieved the physical conditions of the atmospheres from which they emerged using an inversion code implementing discontinuities of the atmospheric parameters along the line of sight. In addition, we use synthetic Stokes profiles from 3D magnetoconvection simulations to complement the results of the inversion. The main features of the synthetic single-lobed profiles are in general agreement with the observed ones, lending support to the magnetic and dynamic topologies inferred from the inversion. The combination of all these different analysis suggests that most of the single-lobed Stokes V profiles are signals coming from magnetic flux emergence and/or submergence processes taking place in small patches in the photospheric of the quiet sun.
description: 21 pages, 26 figures, 1 table
Cell apoptosis induced by ciprofloxacin based Cu(II) complexes: cytotoxicity, SOD mimic and antibacterial studies
Creators: name: Bhatt, Bhupesh S.
name: Gandhi, Divyang H.
name: Vaidya, Foram U.
name: Pathak, Chandramani
name: Patel, Tushar N.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: The current cancer research focuses on the design and synthesis of chemical compounds that can modulate cell apoptosis or programmed cell death. So we synthesized and characterized ciprofloxacin based copper(II) complexes and studied their anticancer activity against HCT 116 cancer cells by MTT assay. We further investigated the influence of compound-2 (better IC50 value than cisplatin) on cancer cells to know the exact mechanism of anticancer activity. The distinct morphological change of cells due to compound-2 was observed in bright field microscopy. The trypan blue assay clearly demonstrated inhibition of cell viability. The clonogenic ability inhibition assay showed a low percentage of the plating efficiency of HCT 116 cells. The mechanism of cell death, either apoptotic or necrotic was distinguished by annexin V-FITC/PI (propidium iodide) staining assay and LDH (lactate dehydrogenase) release assay. The positive annexinV/PI cells in presence of compound-2 and absence of LDH in the LDH release assay confirmed the cell apoptotic mechanism of cell death. We also checked in vitro antibacterial activity of compounds against Gram(−ve) and Gram(+ve) bacteria in terms of MIC (minimum inhibitory concentration) and the data were in good agreement with the standard drug data. SOD mimic activity of synthesized Cu(II) complexes was also studied in terms of IC50 value. The brine shrimp lethality bioassay was also performed to evaluate the cytotoxic properties of the Cu(II) complexes. Communicated by Ramaswamy H. Sarma
Barbara Scholkmann, Burg Baldenstein. Das 'Alte Schloß' bei Gammertingen
Creators: name: Timpel, Wolfgang
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Barbara Scholkmann, Burg Baldenstein. Das 'Alte Schloß' bei Gammertingen. Jan Thorbecke Verlag, Sigmaringen 1982. 76 Seiten, 8 Abbildungen, 16 Tafeln.
description: Bonner Jahrbücher, Bd. 185.1985: Bonner Jahrbücher