cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Delta Blues at the crossroads: the economic revitalisation of the downtown in Clarksdale, Mississippi and lessons for other small cities and towns
Creators: name: Henshall, John
Publisher: name: RMIT University
Year: 2024

description: This thesis provides an assessment of the downtown revitalisation process in Clarksdale, Mississippi, having regard for cultural elements and incorporating a review of literature relating to the role of so-called 'champions' and 'creative people' in driving downtown revitalisation in other cities and towns. The thesis describes the journey embarked upon by the Clarksdale community in its quest for downtown recovery, and highlights the many revitalisation initiatives taken to date. Positive results are evident in new businesses and jobs, improved levels of service, refurbishment of derelict buildings, a renewed sense of place, and an increase in community confidence. The special significance of Blues music and Delta culture to downtown revitalisation is also highlighted through cultural tourism, noting that Clarksdale is situated at the fabled 'crossroads' of Highways 49 and 61 and is also the home to national icons in literature, art and other cultural pursuits. These are key elements around which the Downtown revitalisation effort is focused. Reasons for the decline and revitalisation of Clarksdale are evaluated and related to a broader literature, and lessons are identified to assist downtown revitalisation in other small cities and towns. For many years, the downtown in Clarksdale, with a municipal population 17,600 persons and located in the northern part of the Mississippi Delta, had lost its role as the centre providing a wide range of jobs and services to those living in the surrounding region. Downtown decline has been due largely to the advent of big box retailing and the location of new retail and commercial developments along the State Highway on the edge of town, combined with the loss of jobs and population associated with agricultural restructuring and a loss in manufacturing activity. The thesis emphasises the importance of 'champions' and 'creative people', drawing on community support, in achieving revitalisation. The significance of cultural tourism to Downtown revitalisation is highlighted, with particular emphasis on the global appeal of Blues, but with its roots firmly established in Clarksdale and the Delta. Lessons for other small cities and towns are drawn from the assessment of factors contributing to economic revitalization.
sj-docx-3-dhj-10.1177_20552076231223801 - Supplemental material for ‘It's not everybody's snapshot. It's just an insight into that world’: A qualitative study of multiple perspectives towards understanding the mental health experience and addressing stigma in healthcare students through virtual reality
Creators: name: Szekely, Raul
name: Mason, Oliver
name: Frohlich, David
name: Barley, Elizabeth
Publisher: name: SAGE Journals
Year: 2024
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Nursing not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Aged Health Care
subject: Public Health and Health Services not elsewhere classified
subject: Engineering not elsewhere classified
subject: Anthropology
subject: FOS: Sociology
subject: Cultural Studies not elsewhere classified
subject: Information and Computing Sciences not elsewhere classified
subject: Organisation and Management Theory
subject: Science Policy
subject: Social Policy
subject: Sociology

description: Supplemental material, sj-docx-3-dhj-10.1177_20552076231223801 for ‘It's not everybody's snapshot. It's just an insight into that world’: A qualitative study of multiple perspectives towards understanding the mental health experience and addressing stigma in healthcare students through virtual reality by Raul Szekely, Oliver Mason, David Frohlich and Elizabeth Barley in DIGITAL HEALTH
Coping with cultural differences: the development of generic capabilities in logistics graduates
Creators: name: Christopherson, Geoffrey
Publisher: name: RMIT University
Year: 2024

description: This thesis investigates development of generic capabilities in an RMIT undergraduate logistics degree program. Generic capabilities are those general graduate attributes that are not specifically discipline-focused, examples being communication and teamwork skills. A major research objective of this thesis is the extent to which graduates perceived that generic capabilities were developed in their RMIT logistics undergraduate program, specifically in a cross-cultural context spanning a range of organisations differing in size and ownership structure. The thesis involves two studies. In Study 1 managers from eight organisations, ranging in size from multi-national to small public and private (family-owned) companies were interviewed to develop a series of qualitative organisational case studies using grounded theory methodology. Study 2 is a quantitative survey of 31 Australian and 25 Asian (Singapore and Hong Kong) logistic graduates from 1996 to 2002. In Study 1, generic capabilities rankings in different organisations varied, depending on whether managers being interviewed were operational or human resource management specialists, but there was general agreement that communication, problem-solving, initiative and enterprise, and teamwork skills were highest priority. Study 2 results indicate that the views of both Asian and Australian graduates are in line with the management rankings, and are consistent with those reported by Australian and OECD government and industry research organisations. Both graduate groups agree that generic capabilities are covered in the RMIT logistic program, but ratings are generally in an 'adequate' to 'good' range, with no outstanding features. Although cultural diversity in the student body is seen as a major benefit, there are little data indicating a high level of Australian and Asian student networking, and a number of respondents are critical of a lack of international focus in the present program. A major issue is a n eed for more emphasis on presentation and problem-solving skills so graduates are able to carry through a project from initiation to completion.
Additional file 1 of Cell4D: a general purpose spatial stochastic simulator for cellular pathways
Creators: name: Chan, Donny
name: Cromar, Graham L.
name: Taj, Billy
name: Parkinson, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1: Fig. S1. RMSD values of Cell4D particle and bulk diffusion across multiple timescales.
JUMRv1: a sentiment analysis dataset for movie recommendation
Creators: name: Chatterjee, Shuvamoy
name: Chakrabarti, Kushal
name: Garain, Avishek
name: Schwenker, Friedhelm
name: Sarkar, Ram
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Movie recommendation system
subject: Feature selection
subject: IMDB
subject: Word2Vec
subject: GloVe
subject: DDC 004 / Data processing & computer science
subject: Sentiment analysis
subject: Empfehlungssystem

description: Nowadays, we can observe the applications of machine learning in every field, ranging from the quality testing of materials to the building of powerful computer vision tools. One such recent application is the recommendation system, which is a method that suggests products to users based on their preferences. In this paper, our focus is on a specific recommendation system called movie recommendation. Here, we make use of user reviews of movies in order to establish a general outlook about the movie and then use that outlook to recommend that movie to other users. However, a huge number of available reviews has baffled sophisticated review systems. Consequently, there is a need to find a method of extracting meaningful information from the available reviews and use that in classifying a movie review and predicting the sentiment in each one. In a typical scenario, a review can either be positive, negative, or indifferent about a movie. However, the available research articles in the field mainly consider this as a two-class classification problem—positive and negative. The most popular work in this field was performed on Stanford and Rotten Tomatoes datasets, which are somewhat outdated. Our work is based on self-scraped reviews from the IMDB website, and we have annotated the reviews into one of the three classes—positive, negative, and neutral. Our dataset is called JUMRv1—Jadavpur University Movie Recommendation dataset version 1. For the evaluation of JUMRv1, we took an exhaustive approach by testing various combinations of word embeddings, feature selection methods, and classifiers. We also analysed the performance trends, if there were any, and attempted to explain them. Our work sets a benchmark for movie recommendation systems that is based on the newly developed dataset using a three-class sentiment classification.
Planning in BDI agent systems
Creators: name: De Silva, Lavindra
Publisher: name: RMIT University
Year: 2024

description: Belief-Desire-Intention (BDI) agent systems are a popular approach to developing agents for complex and dynamic environments. These agents rely on context sensitive expansion of plans, acting as they go, and consequently, they do not incorporate a generic mechanism to do any kind of “look-ahead” or offline planning. This is useful when, for instance, important resources may be consumed by executing steps that are not necessary for a goal; steps are not reversible and may lead to situations in which a goal cannot be solved; and side effects of steps are undesirable if they are not useful for a goal. In this thesis, we incorporate planning techniques into BDI systems.

First, we provide a general mechanism for performing “look-ahead” planning, using Hierarchical Task Network (HTN) planning techniques, so that an agent may guide its selection of plans for the purpose of avoiding negative interactions between them. Unlike past work on adding such planning into BDI agents, which do so only at the implementation level without any precise semantics, we provide a solid theoretical basis for such planning.

Second, we incorporate first principles planning into BDI systems, so that new plans may be created for achieving goals. Unlike past work, which focuses on creating low-level plans, losing much of the domain knowledge encoded in BDI agents, we introduce a novel technique where plans are created by respecting and reusing the procedural domain knowledge encoded in such agents; our abstract plans can be executed in the standard BDI engine using this knowledge. Furthermore, we recognise an intrinsic tension between striving for abstract plans and, at the same time, ensuring that unnecessary actions, unrelated to the specific goal to be achieved, are avoided. To explore this tension, we characterise the set of “ideal” abstract plans that are non-redundant while maximally abstract, and then develop a more limited but feasible account where an abstract plan is “specialised” into a plan that is non-redundant and as abstract as possible.

We present theoretical properties of the planning frameworks, as well as insights into their practical utility.
Project Management Plan - D1.1 Invade H2020
Creators: name: Hirdes, Dieter
Publisher: name: Zenodo
Year: 2017
Subjects: INVADE
Flexibility
Smart Grids
H2020
Electric vehicles
Batteries

description: This deliverable establishes the Project Management Plan for the INVADE project. The plan includes all the processes and articulates the responsibilities at person/partner level in order to ensure the production of high-quality results in line with the project plan as described in the Description of Action. It establishes also the Quality Plan and the Risk Management and Contingency Plan
Complexity of respirable dust found in mining operations as characterized by X-ray diffraction and FTIR analysis
Creators: name: Walker, Rachel
name: Cauda, Emanuele
name: Chubb, Lauren
name: Krebs, Patrick
name: Stach, Robert
name: Mizaikoff, Boris
name: Johnston, Cliff
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: respirable mine dust
subject: PCA
subject: FTIR spectroscopy
subject: XRD
subject: direct-on-filter
subject: DDC 620 / Engineering & allied operations
subject: Principal components analysis
subject: Fourier transform infrared spectroscopy
subject: Mineralogy
subject: Hauptkomponentenanalyse
subject: FT-IR-Spektroskopie
subject: Röntgendiffraktometrie
subject: Mineralogie

description: The mineralogical complexity of mine dust complicates exposure monitoring methods for occupational, respirable hazards. Improved understanding of the variability in respirable dust characteristics, e.g., mineral phase occurrence and composition, is required to advance on-site monitoring techniques that can be applied across diverse mining sectors. Principal components analysis (PCA) models were applied separately to XRD and FTIR datasets collected on 130 respirable dust samples from seven mining commodities to explore similarities and differences among the samples. Findings from both PCA models classified limestone, iron, and granite mine samples via their analytical responses. However, the results also cautioned that respirable samples from these commodities may not always fit patterns observed within the model. For example, one unique sample collected in a limestone mine contained no carbonate minerals. Future predictive quantification models should account for unique samples. Differences between gold and copper mine dust samples were difficult to observe. Further investigation suggested that the key to their differentiation by FTIR may lie in the characterization of clays. The results presented in this study provide foundational information for guiding the development of quantification models for respirable mineral hazards in the mining industry.
Optimising mixed-grazing strategies for semi-arid Australian rangelands
Creators: name: Moloney, Paul
Publisher: name: RMIT University
Year: 2024

description: Currently in semi-arid Australian rangelands properties produce mainly beef and wool on marginal lands. A major area of concern is grazing pressure. Kangaroos are considered to have a considerable impact on grazing pressure, and for that reason they are often considered pests by landholders. It has been thought that converting from farming European stock to native wildlife would have environmental benefits. The commercial benefits from the change are unclear. Through construction of a plant-herbivore model, the dynamics of cattle, sheep and kangaroo commodities are examined. Simulations were constructed so as to estimate the expected value for each and the correlation between the different commodities. Portfolio analysis using mean-variance, average value-at-risk, and multi-objective optimisation projects were used to analyse different allocations of forage to each herbivore. The effect of an enforced reduction in methane emissions is also explored. From the analysis it seems that diversification of herbivores (including kangaroos) is optimal on marginal lands, for the risk adverse, and to reduce methane emissions.
Additional file 2 of Cell4D: a general purpose spatial stochastic simulator for cellular pathways
Creators: name: Chan, Donny
name: Cromar, Graham L.
name: Taj, Billy
name: Parkinson, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 2: Fig. S2. RMSD of Cell4D bulk molecule diffusion and particle diffusion across space scales.
sj-docx-1-mrj-10.1177_00222437221110139 - Supplemental material for Algorithmic Transference: People Overgeneralize Failures of AI in the Government
Creators: name: Longoni, Chiara
name: Cian, Luca
name: Kyung, Ellie J.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 150402 Hospitality Management
subject: FOS: Economics and business

description: Supplemental material, sj-docx-1-mrj-10.1177_00222437221110139 for Algorithmic Transference: People Overgeneralize Failures of AI in the Government by Chiara Longoni, Luca Cian and Ellie J. Kyung in Journal of Marketing Research
Experimental study on circularly towed aerial tethers
Creators: name: Lapthorne, Peter
Publisher: name: RMIT University
Year: 2024

description: Understanding the behaviour of towed objects is key in many disciplines. For example, towed underwater equipment for geological survey, or space applications such as “slingshot” deployment of satellites.

In the airborne case, the free end of a long, circularly towed cable will become almost stationary below the centre of the tow vehicle circle. This near-stationary state offers promise of a payload delivery and retrieval technique. Many contributions have been made of modelling and analysis methods which have provided solid understanding of the behaviour of an ideal airborne, circularly-towed system.

Fewer contributions exist of experimental results. This Thesis responds to that lack by documenting a series of experiments conducted by the author, which specifically explored the behaviour of small scale systems and a single full scale system.

In the course of the experimental program, several behaviours, not predicted by analytical work to date, were observed. One was further explored and also analysed, using an existing model. This demonstrated that the model used could yield results consistent with the observed behaviour.

Observation of these unpredicted behaviours has identified several areas where further work is required, in order to move closer to a practical realisation of the payload delivery concept.

The key contributions of this Thesis are the identification of previously unknown tether behaviours and experimental data which can be used for verification of existing models.
Extended role-based access control model for enterprise systems and web services
Creators: name: Shi, Wei
Publisher: name: RMIT University
Year: 2024

description: This thesis intends to develop application-level access control models to address several major security issues in enterprise environments. The first goal is to provide simple and efficient authorization specifications to reduce the complexity of security management. The second goal is to provide dynamic access control for Web service applications. The third goal is to provide an access control framework for Semantic Web services. In this thesis, an Authorization-Function-Based Role-based Access Control (FB-RBAC) model is proposed for controlling enterprise systems at the application level. The unique features of the proposed model are authorization-function-based access control and constraint-based finegrained access control. This model significantly simplifies the management of an access control system by adopting roles and authorization-functions in authorization specifications. An extension of FB-RBAC, Extended FB-RBAC (ERBAC), is applied to Web service applications. New features such as credential-based access control and dynamic role assignment are added to FB-RBAC in order to address user heterogeneity and dynamicity in the Web environment. The proposed ERBAC model is then extended to support Semantic Web services. Each component of the ERBAC model is described by security ontologies. These correlated security ontologies are integrated with Semantic Web services to form a complete ontology network. Ontology-based role assignment is facilitated so that security information can be queries and discovered through a network of ontologies.
Optically transparent patch antennas at 77 GHz using meshed aluminum
Creators: name: Hügler, Philipp
name: Zaky, Mohamad
name: Roos, Michael
name: Strehle, Steffen
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Transparent antenna
subject: Millimeter wave technology
subject: Fused silica
subject: DDC 620 / Engineering & allied operations
subject: Antennas (Electronics)
subject: Millimeter waves
subject: Silica
subject: Patch-Antenne
subject: Millimeterwelle
subject: Quarzglas

description: A process to realize optically transparent patch antennas with double-sided aluminum metalization of meshed structures on fused silica is presented in this paper. For cost-saving manufacturing, aluminum is used as metalization and wire-bonding is chosen as an industry standard RF interconnection technique. Despite the fact that aluminum has a lower conductivity compared to silver or gold, 64 % and 81 % transparent antennas at 77 GHz with 4.4 dBi and 3.7 dBi gain respectively were realized.
sj-docx-1-acr-10.1177_02841851221130612 - Supplemental material for Virtual monoenergetic images by spectral detector computed tomography may improve image quality and diagnostic ability for ischemic lesions in acute ischemic stroke
Creators: name: Mellander, Helena
name: Bengtsson, Pär
name: Fransson, Veronica
name: Ramgren, Birgitta
name: Undrén, Per
name: Drake, Mattias
name: Ydström, Kristina
name: Lätt, Jimmy
name: Hilal, Amir
name: Wassélius, Johan
name: Ullberg, Teresa
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110320 Radiology and Organ Imaging
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-acr-10.1177_02841851221130612 for Virtual monoenergetic images by spectral detector computed tomography may improve image quality and diagnostic ability for ischemic lesions in acute ischemic stroke by Helena Mellander, Pär Bengtsson, Veronica Fransson, Birgitta Ramgren, Per Undrén, Mattias Drake, Kristina Ydström, Jimmy Lätt, Amir Hilal, Johan Wassélius and Teresa Ullberg in Acta Radiologica
Additional file 3 of Cell4D: a general purpose spatial stochastic simulator for cellular pathways
Creators: name: Chan, Donny
name: Cromar, Graham L.
name: Taj, Billy
name: Parkinson, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 3: Fig. S3. Reaction products generated from unimolecular and two-particle bimolecular reactions over time.
The effects of intranasal oxytocin on neural and behavioral responses to social touch in the form of massage
Creators: name: Chen, Yuanshu
name: Li, Qin
name: Zhang, Qianqian
name: Kou, Juan
name: Zhang, Yingying
name: Cui, Han
name: Wernicke, Jennifer
name: Montag, Christian
name: Becker, Benjamin
name: Kendrick, Keith M.
name: Yao, Shuxia
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: social massage
subject: reward response
subject: autism traits
subject: fMRI
subject: Social perception
subject: Autism
subject: Oxytocin
subject: Autistic disorder
subject: Magnetic resonance imaging
subject: Soziale Wahrnehmung
subject: Autismus
subject: Oxytocin
subject: Funktionelle Kernspintomografie

description: Manually-administered massage can potently increase endogenous oxytocin concentrations and neural activity in social cognition and reward regions and intranasal oxytocin can increase the pleasantness of social touch. In the present study, we investigated whether intranasal oxytocin modulates behavioral and neural responses to foot massage applied manually or by machine using a randomized placebo-controlled within-subject pharmaco-fMRI design. 46 male participants underwent blocks of massage of each type where they both received and imagined receiving the massage. Intranasal oxytocin significantly increased subjective pleasantness ratings of the manual but not the machine massage and neural responses in key regions involved in reward (orbitofrontal cortex, dorsal striatum and ventral tegmental area), social cognition (superior temporal sulcus and inferior parietal lobule), emotion and salience (amygdala and anterior cingulate and insula) and default mode networks (medial prefrontal cortex, parahippocampal gyrus, posterior cingulate, and precuneus) as well as a number of sensory and motor processing regions. Both neural and behavioral effects of oxytocin occurred independent of whether subjects thought the massage was applied by a male or female masseur. These findings support the importance of oxytocin for enhancing positive behavioral and neural responses to social touch in the form of manually administered massage and that a combination of intranasal oxytocin and massage may have therapeutic potential in autism. Clinical Trials Registration The Effects of Oxytocin on Social Touch; registration ID: NCT03278860; URL: https://clinicaltrials.gov/ct2/show/NCT03278860.
sj-docx-4-hss-10.1177_15563316221129556 – Supplemental material for Impact of Large Database Studies on Orthopedic Surgery Literature: Are We Advancing the Field?
Creators: name: N. Tornberg, Haley
name: Cohen, Jordan S.
name: Gu, Alex
name: Wei, Chapman
name: Mortman, Ryan
name: Sculco, Peter K.
name: Thakkar, Savyasachi C.
name: Campbell, Joshua C.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-4-hss-10.1177_15563316221129556 for Impact of Large Database Studies on Orthopedic Surgery Literature: Are We Advancing the Field? by Haley N. Tornberg, Jordan S. Cohen, Alex Gu, Chapman Wei, Ryan Mortman, Peter K. Sculco, Savyasachi C. Thakkar and Joshua C. Campbell in HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery
sj-pdf-2-jfm-10.1177_1098612X221128760 – Supplemental material for 2022 AAFP/ISFM Cat Friendly Veterinary Interaction Guidelines: Approach and Handling Techniques
Creators: name: Rodan, Ilona
name: Dowgray, Nathalie
name: Carney, Hazel C
name: Carozza, Ellen
name: Ellis, Sarah LH
name: Heath, Sarah
name: Niel, Lee
name: St Denis, Kelly
name: Taylor, Samantha
Publisher: name: SAGE Journals
Year: 2022
Subjects: Veterinary Medicine

description: Supplemental material, sj-pdf-2-jfm-10.1177_1098612X221128760 for 2022 AAFP/ISFM Cat Friendly Veterinary Interaction Guidelines: Approach and Handling Techniques by Ilona Rodan, Nathalie Dowgray, Hazel C Carney, Ellen Carozza, Sarah LH Ellis, Sarah Heath, Lee Niel, Kelly St Denis and Samantha Taylor in Journal of Feline Medicine and Surgery
Additional file 4 of Cell4D: a general purpose spatial stochastic simulator for cellular pathways
Creators: name: Chan, Donny
name: Cromar, Graham L.
name: Taj, Billy
name: Parkinson, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 4: Fig. S4. Summary of bimolecular products over time of bulk-particle reactions using a Smoluchowski-based method to calculate reaction probability.
sj-pdf-1-ajs-10.1177_03635465221124917 – Supplemental material for Effects of Initial Graft Tension and Patient Sex on Knee Osteoarthritis Outcomes After ACL Reconstruction: A Randomized Controlled Clinical Trial With 10- to 12-Year Follow-up
Creators: name: Costa, Meggin Q.
name: Badger, Gary J.
name: Chrostek, Cynthia A.
name: Carvalho, Orianna D.
name: Faiola, Stacy L.
name: Fadale, Paul D.
name: Hulstyn, Michael J.
name: Gil, Holly C.
name: Shalvoy, Robert M.
name: Fleming, Braden C.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_03635465221124917 for Effects of Initial Graft Tension and Patient Sex on Knee Osteoarthritis Outcomes After ACL Reconstruction: A Randomized Controlled Clinical Trial With 10- to 12-Year Follow-up by Meggin Q. Costa, Gary J. Badger, Cynthia A. Chrostek, Orianna D. Carvalho, Stacy L. Faiola, Paul D. Fadale, Michael J. Hulstyn, Holly C. Gil, Robert M. Shalvoy and Braden C. Fleming in The American Journal of Sports Medicine
Correlation of HPV16 gene status and gene expression with antibody seropositivity and TIL status in OPSCC
Creators: name: Von Witzleben, Adrian
name: Currall, Eve
name: Wood, Oliver
name: Chudley, Lindsey
name: Akinyegun, Oluyemisi
name: Thomas, Jaya
name: Bendjama, Kaïdre
name: Thomas, Gareth J.
name: Friedmann, Peter S.
name: King, Emma V.
name: Laban, Simon
name: Ottensmeier, Christian H.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: oropharyngeal squamous cell carcinoma
subject: antibody isotype
subject: immune response
subject: DDC 610 / Medicine & health
subject: Human papillomavirus 16
subject: Squamous cell carcinoma of head and neck
subject: Gene expression
subject: Immunity
subject: Humanes Papillomavirus
subject: Plattenepithelcarcinom
subject: Immunreaktion
subject: Genexpression

description: Introduction Human papillomavirus 16 (HPV16) is the main cause of oropharyngeal squamous cell carcinoma (OPSCC). To date, the links between HPV16 gene expression and adaptive immune responses have not been investigated. We evaluated the correlation of HPV16 DNA, RNA transcripts and features of adaptive immune response by evaluating antibody isotypes against E2, E7 antigens and density of tumor-infiltrating lymphocytes (TIL). Material and Methods FFPE-tissue from 27/77 p16-positive OPSCC patients was available. DNA and RNA were extracted and quantified using qPCR for all HPV16 genes. The TIL status was assessed. Immune responses against E2 and E7 were quantified by ELISA (IgG, IgA, and IgM; 77 serum samples pre-treatment, 36 matched post-treatment). Results Amounts of HPV16 genes were highly correlated at DNA and RNA levels. RNA co-expression of all genes was detected in 37% (7/19). E7 qPCR results were correlated with higher anti-E7 antibody (IgG, IgA) level in the blood. Patients with high anti-E2 IgG antibody (>median) had better overall survival (p=0.0311); anti-E2 and anti-E7 IgA levels had no detectable effect. During the first 6 months after treatment, IgA but not IgG increased significantly, and >6 months both antibody classes declined over time. Patients with immune cell-rich tumors had higher levels of circulating antibodies against HPV antigens. Conclusion We describe an HPV16 qPCR assay to quantify genomic and transcriptomic expression and correlate this with serum antibody levels against HPV16 oncoproteins. Understanding DNA/RNA expression, relationship to the antibody response in patients regarding treatment and outcome offers an attractive tool to improve patient care.
Acute DWI reductions in patients after single epileptic seizures - more common than assumed
Creators: name: Hübers, Annemarie
name: Thoma, Katharina
name: Schocke, Michael
name: Fauser, Susanne
name: Ludolph, Albert C.
name: Kassubek, Jan Rainer
name: Pinkhardt, Elmar Hans
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: diffusion weighted imaging
subject: seizure
subject: status epilepticus
subject: DDC 610 / Medicine & health
subject: Epilepsy; Diagnostic imaging
subject: Diffusion magnetic resonance imaging
subject: Magnetic resonance imaging
subject: Epilepsie
subject: Diffusionsgewichtete Magnetresonanztomografie

description: Background: Changes of cerebral diffusivity detected by magnetic resonance imaging (MRI) have been reported in epilepsy. Diffusion weighted imaging (DWI) detects changes in the distribution of water molecules by measuring the apparent diffusion coefficient (ADC) and is mainly used in the diagnosis of ischemic stroke. DWI changes in epilepsy were reported in status epilepticus (SE) or series of seizures. It remains unclear whether this phenomenon also occurs after single seizures. Accordingly, possible pathomechanisms have only been discussed on the presumed basis of ongoing epileptic brain activity. Methods: In this retrospective study, we systematically analyzed DWI alterations related to epileptic seizures in 454 patients who received MRI scanning within the first 24 h after seizure onset. Results: DWI restrictions not classified as ischemic stroke were observed in 18 patients (4%). We found DWI restrictions in 19% of patients with SE/seizure series and in 3% of patients after single focal and 2.5% after single generalized seizures. 17 patients with DWI alterations were diagnosed with a structural epilepsy. DWI signal decreased in the majority of patients within the first days and could not be detected in follow-up imaging >3 months. In all patients except one, DWI alterations were detected in the same hemisphere as the lesion. In the case of seizure series or SE, DWI restrictions mostly presented with a typical “garland-like” pattern alongside the cortical band or on the border of a defined lesion, while in isolated seizures, the restrictions were often rather subtle and small. Discussion: We show that DWI restrictions can be observed in patients after single epileptic seizures. As the vast majority of these patients was diagnosed with an epilepsy due to structural cerebral pathology, DWI restriction may reflect a higher vulnerability in these regions. This might also explain the fact that diffusivity changes were observed after single focal seizures as well as after multiple seizures or SE. The occurence itself on one side as well as the spatial pattern of this phenomenon on the other may thus not only be related to the duration of ictal activity, but to structural pathology.
Behaviour of viruses in biosolids
Creators: name: Chellappan, Sriharini
Publisher: name: RMIT University
Year: 2024

description: Biosolids refers to the stabilized sewage sludge produced in wastewater treatment which is destined for beneficial purposes as a fertilizer and soil conditioner. In addition to nutrients and organic matter, biosolids may contain pathogens including bacteria, viruses, helminths and parasites. The current Victorian guidelines to produce T1 treatment grade biosolids (unrestricted use) require the sludge to be stored for a minimum of three years after the pan drying process to ensure destruction of pathogens. This long term storage is associated with problems such as loss of nutrients in biosolids management costs incurred in maintaining stockpiles of sludge and increased greenhouse gas emissions from the stockpiles. This study evaluates whether microbiological criteria with respect to viruses can be achieved with a shorter treatment time. This data will be provided to regulatory authorities prior to their revision of current Victorian guidelines. In this study, adenovirus was chosen as indicator pathogen for enteric viruses. Primary objectives of this project include: (i) development of standard qPCR method for the detection of adenovirus in sewage sludge, (ii) determining the treatment time required by adenoviruses to achieve prescribed microbiological criteria through laboratory simulation of pan drying and stockpiling processes of sludge collected from both metropolitan and regional wastewater treatment systems (iii) finding the levels of human adenobirus 41 (HAdV 41) in metropolitan sludge at different stages of the treatment process (output from mesophilic anaerobic digester, drying pans of different ages) and regional sludge treatment systems (lagoon sludge) in Victoria. These studies will be used to determine whether adenviruses could serve as better indicator organisms than coliphages in biosolids treatment.
Additional file 5 of Cell4D: a general purpose spatial stochastic simulator for cellular pathways
Creators: name: Chan, Donny
name: Cromar, Graham L.
name: Taj, Billy
name: Parkinson, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 5: Fig. S5. Summary of two-particle bimolecular products over time using the Andrews-Bray adjusted Smoluchowski method to calculate reaction radii.
Communication design and the other: investigating the intersubjective in practice
Creators: name: Haslem, Neal
Publisher: name: RMIT University
Year: 2024

description: This research investigates the intersubjective aspects of communication design practice through a focus on the other, and the roles that the other takes in practice. It does so in order to better understand the practice of communication design as practiced on a day-to-day basis.

Communication design, as a practice, and a field, extends out of graphic design. This extension is due to a change in priorities; from privileging the graphic and artefactual aspects of practice, to prioritising the consideration of the broader agency of design within a specific context.

This research has been accomplished through a practice-led methodology. Communication design projects form the methods of, and the foundation for, the investigation. Seven individual research projects have been designed and carried out. These projects have each incorporated members of the different participants of communication design practice; new and existing clients, student designers and established practicing designers. This has allowed the research to investigate its concerns from a range of roles and viewpoints, incorporating different perspectives into its observations and understandings.

This research extends the work of Donald Schön and his investigation into The Reflective Practitioner (1983). It achieves this through a consideration for the roles of the other in professional practice. In order to articulate this move extensive reference is made to the thinking of the twentieth century philosophers Martin Heidegger and Emmanuel Levinas.

This research has found that the other plays critical roles in the practice of communication design. These roles are ones of providing provocative disjunction. Provocative disjunction, as understood by this research, contributes directly to the generative action communication design offers artefacts, clients and designers.

The observations and understandings of this practice-led research have enabled extensive insights into the practice of communication design. These insights contribute significantly to the broader communication design discourse in professional practice, education and research.
The practice of m3architecture
Creators: name: Vielle, Benjamin
Publisher: name: RMIT University
Year: 2024

description: m3architecture's research into practice, summarised by a series of posters, captures the territory between thinking and building. The posters are m3architecture projects in their own right. They are conceived using the same themes, interests and techniques inherent in the production, and visible in the outcomes of the built work. The material offers a concurrent understanding of project by theme and theme by project. The thesis includes a summary of built work, the search for an understanding of practice, and the search and the expression of the individual and collective practice of m3architecture.
Existential problems in the novel: the character and his world
Creators: name: Morrison, Julie-Ann
Publisher: name: RMIT University
Year: 2024

description: This exegesis investigates techniques for the creation of literary characters using Milan Kundera as theorist and F.Scott Fitzgerald as practitioner. The universality of Milan Kundera’s theory of basing characters on existential problems is tested in the case study, The Great Gatbsy, by F.Scott Fitzerald. Kundera and Fitzgerald’s contrasting techniques for character construction are investigated to reveal how existential problems can operate as both literary devices and themes. The essential difference between Kundera’s and Fitzgerald’s treatment of existential problems is that Kundera uses existential problems to create characters and Fitzgerald uses characters to create the existential problem of the world of the novel. Through investigation of Kundera’s and Fitzgerald’s techniques and reflection on the process of writing the project novel, The Luna Museum, a new insight into how existential problems operate within the structure of literary characters is defined by the identification of three components: the impulse (from the character’s self); the catalyst (from the character’s experience); the means to act (available within the world of the novel). These components can be used to create and analyse literary characters for the purposes of writing and editing literary fiction.
Autologous mesenchymal stroma cells are superior to allogeneic ones in bone defect regeneration
Creators: name: Rapp, Anna E.
name: Bindl, Ronny
name: Erbacher, Annika
name: Kruchen, Anne
name: Rojewski, Markus
name: Schrezenmeier, Hubert
name: Müller, Ingo
name: Ignatius, Anita
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: large bone defect
subject: humanized mouse
subject: allogeneic
subject: stem cells
subject: MSC
subject: DDC 610 / Medicine & health
subject: Bone regeneration
subject: Mesenchymal stem cells
subject: Regenerative medicine; Methods
subject: Knochenregeneration
subject: Mesenchymzelle

description: The application of autologous mesenchymal stem cells (MSC) for the treatment of bone defects requires two invasive procedures and several weeks of ex vivo cell expansion. To overcome these limitations, the administration of allogeneic MSC may be attractive, because they are anticipated to be immunoprivileged. Because preclinical studies using various animal models are conflicting with respect to the efficacy of allogeneic MSC, we investigated whether autologous and allogeneic human MSC (hMSC) are equally effective in regenerating bone in a humanized mouse model resembling the human immune system. Applying autologous and allogeneic hMSC in critically sized femoral defects, we found that allogeneic hMSC elicited a mild immune response early after implantation, whereas early angiogenic processes were similar in both treatments. At later healing time points, the transplantation of allogeneic hMSC resulted in less bone formation than autologous hMSC, associated with a reduced expression of the osteogenic factor Runx2 and impaired angiogenesis. We found by species-specific staining for collagen-type-1α2 that MSCs of either source did not synthesize new bone matrix, indicating an indirect contribution of transplanted hMSC to bone regeneration. In conclusion, our data suggest that the application of autologous hMSC is superior to that of allogeneic cells for bone defect treatment.
Additional file 6 of Cell4D: a general purpose spatial stochastic simulator for cellular pathways
Creators: name: Chan, Donny
name: Cromar, Graham L.
name: Taj, Billy
name: Parkinson, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 6: Fig. S6. Saturation of calmodulin under varying calcium concentrations in well-mixed or microdomain conditions.
Thermophysical properties of Fe-Si and Cu-Pb melts and their effects on solidification related processes
Creators: name: Novakovic, Rada
name: Giuranno, Donatella
name: Lee, Joonho
name: Mohr, Markus
name: Delsante, Simona
name: Borzone, Gabriella
name: Miani, Fabio
name: Fecht, Hans-Jörg
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Cu-Pb
subject: Fe-Si alloys
subject: modelling
subject: molar volume
subject: short-range ordering
subject: DDC 620 / Engineering & allied operations
subject: Surface tension
subject: Viscosity
subject: Molecular volume
subject: Oberflächenspannung
subject: Viskosität

description: Among thermophysical properties, the surface/interfacial tension, viscosity, and density/molar volume of liquid alloys are the key properties for the modelling of microstructural evolution during solidification. Therefore, only reliable input data can yield accurate predictions preventing the error propagation in numerical simulations of solidification related processes. To this aim, the thermophysical properties of the Fe-Si and Cu-Pb systems were analysed and the connections with the peculiarities of their mixing behaviours are highlighted. Due to experimental difficulties related to reactivity of metallic melts at high temperatures, the measured data are often unreliable or even lacking. The application of containerless processing techniques either leads to a significant improvement of the accuracy or makes the measurement possible at all. On the other side, accurate model predicted property values could be used to compensate for the missing data; otherwise, the experimental data are useful for the validation of theoretical models. The choice of models is particularly important for the surface, transport, and structural properties of liquid alloys representing the two limiting cases of mixing, i.e., ordered and phase separating alloy systems.
A Steady-State Monte Carlo Study on the Effect of Structural and Operating Parameters on Liquid Water Distribution within the Microporous Layers and the Catalyst Layers of PEM Fuel Cells
Creators: name: Pournemat, A.
name: Wilhelm, F.
name: Haußmann, J.
name: Vierrath, S.
name: Thiele, S.
name: Scholta, J.
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Fuel Cells - PEM
subject: DDC 620 / Engineering & allied operations
subject: Fuel cells
subject: Brennstoffzelle

description: The distribution of liquid water agglomerations within a catalyst layer and a microporous layer of a polymer electrolyte membrane fuel cell employing a Monte Carlo model are simulated. The simulations are based on real material structures and locally resolved operating conditions. The 3D material structures are obtained from focused ion beam tomography capable of nm-scale imaging. The local temperature and the relative humidity profiles are provided by a computational fluid dynamics simulation, based on a single channel fuel cell model taking into account all relevant transport and electrochemical processes. The results of this Monte Carlo study confirm the strong dependency of the water saturation in the catalyst layer and microporous layer on the structural parameters and operating conditions, such as: wettability, pore size and local temperature and relative humidity.
Additional file 7 of Cell4D: a general purpose spatial stochastic simulator for cellular pathways
Creators: name: Chan, Donny
name: Cromar, Graham L.
name: Taj, Billy
name: Parkinson, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 7: Fig. S7. Comparison of surface CEACAM1 clustering in both Cell4D model variants.
Online Appendix of "Modeling the origins of communication: Alignment of interests and social cues thereof"
Creators: name: Mühlenbernd, Roland
Publisher: name: figshare
Year: 2022
Subjects: subject: 209999 Language, Communication and Culture not elsewhere classified
subject: FOS: Languages and literature

description: Online Appendix of the article "Modeling the origins of communication: Alignment of interests and social cues thereof" by Roland Muuhlenbernd and Andreas Baumann, published in the Proceedings of the Joint Conference on Language Evolution 2022 (JCoLE).
A representation-free description of the Kasevich–Chu interferometer: a resolution of the redshift controversy
Creators: name: Schleich, Wolfgang P
name: Greenberger, Daniel M
name: Rasel, Ernst M
Publisher: name: Universität Ulm
Year: 2013
Subjects: subject: DDC 530 / Physics
subject: Atom interferometry
subject: Operator algebras
subject: Atominterferometrie

description: Abstract Motivated by a recent claim by Müller et al (2010 Nature 463 926–9) that an atom interferometer can serve as an atom clock to measure the gravitational redshift with an unprecedented accuracy, we provide a representation-free description of the Kasevich–Chu interferometer based on operator algebra. We use this framework to show that the operator product determining the number of atoms at the exit ports of the interferometer is a c-number phase factor whose phase is the sum of only two phases: one is due to the acceleration of the phases of the laser pulses and the other one is due to the acceleration of the atom. This formulation brings out most clearly that this interferometer is an accelerometer or a gravimeter. Moreover, we point out that in different representations of quantum mechanics such as the position or the momentum representation the phase shift appears as though it originates from different physical phenomena. Due to this representation dependence conclusions concerning an enhanced accuracy derived in a specific representation are unfounded.