cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cardiocephaloides brandesii
Creators: name: Dronen, Norman O.
name: Blend, Charles K.
name: Gardner, Scott L.
name: Jiménez, F. Agustín
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Platyhelminthes
Trematoda
Diplostomida
Strigeidae
Cardiocephaloides
Cardiocephaloides brandesii

description: Cardiocephaloides brandesii (Szidat, 1928) Localities: Bryan Utility Lake, Bryan, Brazos County, Texas, U.S.A., 30° 24' N latitude, 96° 13' W longitude; Galveston Bay, Galveston County, Texas, U.S.A., 29 Ο 18' N latitude, 94 Ο 48' W longitude. Site of infection: intestine. Deposited specimens: Voucher specimens (5 specimens) HWML 48504. Prevalence: 3 of 4 birds, 75%. Mean intensity: 14 individuals/infected bird. Basic comparative description: Based on 10 adult specimens. Body elongate, aspinose, 5,860 (4,625 – 7,950) long with relatively short forebody 925 (800–1,200) by 670 (480–825) divided by distinct constriction from longer hindbody 4,875 (3,700 –6,750) by 800 (750–850). Oral sucker 75 (50–100) by 75 (60–90); prepharynx absent; pharynx 65 (60–70) by 45 (40–55); esophagus 30 (25–40) long; ceca long, terminating near posterior extremity. Acetabulum 90 (75–95) by 95 (75–105). Testes tandem, anterior testis 475 (430– 570) by 420 (345–500); posterior testis 535 (440–680) by 460 (395–550). Genital pore terminal. Ovary oval, immediately anterior to and usually contiguous with anterior testis, 235 (220–250) by 245 (230–260). Vitellaria restricted to hindbody. Eggs 103 (85–107) by 68 (63–73). Remarks. This species has previously been reported from the royal tern by Rietschel & Werding (1978) from the western hemisphere (see Table 1).
description: Published as part of Dronen, Norman O., Blend, Charles K., Gardner, Scott L. & Jiménez, F. Agustín, 2007, Stictodora cablei n. sp. (Digenea: Heterophyidae) from the royal tern, Sterna maxima (Laridae: Sterninae) from Puerto Rico and the Brazos County area of the Texas Gulf coast, U. S. A., with a list of other endohelminths recovered in Texas, pp. 35-56 in Zootaxa 1432 (1) on page 53, DOI: 10.11646/zootaxa.1432.1.3, http://zenodo.org/record/5077195
description: {"references": ["Rietschel, G. & Werding, B. (1978) Trematodes from birds from northern Colombia. Zetschrift fur Parasitenkunde, 57, 57 - 82."]}
PAM: When Overloaded, Push Your Neighbor Aside!
Creators: name: Meng, Zili
name: Bi, Jun
name: Sun, Chen
name: Wang, Shuhe
name: Wang, Minhu
name: Hu, Hongxin
Publisher: name: arXiv
Year: 2018
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Performance (cs.PF)
subject: FOS: Computer and information sciences

description: Recently SmartNICs are widely used to accelerate service chains in NFV. However, when the SmartNIC is overloaded, casually migrating vNFs away from SmartNIC to CPU may lead to additional packet transmissions between SmartNIC and CPU. To address this problem, we present PAM, push aside migration to effectively alleviate the hot spot on SmartNIC with no performance overhead. Our key novelty is to push vNFs on the border of SmartNIC and CPU aside to release resources for the bottleneck vNF. Evaluation shows that PAM could efficiently alleviate the hot spot on SmartNIC and generate a service chain with much lower latency compared with the naive solution.
description: In Proceedings of ACM SIGCOMM 2018 Conference Posters and Demos
Additional file 6: of Pathogenic functions of host microbiota
Creators: name: Rath, Silke
name: Rud, Tatjana
name: AndrĂŠ Karch
name: Pieper, Dietmar
name: Vital, Marius
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Results of screening procedures for grdH sequences. In Panel A obtained unique proteins are depicted along the x-axis, sorted according to their similarity to the constructed hidden Markov chain model (HMM) represented by the primary y-axis. The secondary y-axis shows phylogenetic distances to the top-scoring sequence (triangles). Sequences considered as true grdH are shown in blue. Below (B) a tree of all sequences from Panel A is displayed with the clade containing true grdH sequences highlighted in blue. Sequences encoding glycine reductase (grdB: Q9R4G8-1) and sarcosine reductase (grdF: O86186-1) are shown in pink (UniProt IDs are given). (PDF 127 kb)
Extracting factors associated with vaccination from Twitter data and mapping to behavioral models
Creators: name: Biswas, Md. Rafiul
name: Shah, Zubair
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Social media platform, particularly Twitter, is a rich data source that allows monitoring of public opinions and attitudes toward vaccines.Established behavioral models like the 5C psychological antecedents model and the Health Belief Model (HBM) provide a well-structured framework for analyzing shifts in vaccine-related behavior. This study examines if the extracted data from Twitter contains valuable insights regarding public attitudes toward vaccines and can be mapped to two behavioral models. This study focuses on the Arab population, and a search was carried out on Twitter using: ’ تلقيحي OR تطعيم OR تطعيمات OR لقاح OR لقاحات’ for two years from January 2020 to January 2022. Then, BERTopicmodeling was applied, and several topics were extracted. Finally, the topics were manually mapped to the factors of the 5C model and HBM. 1,068,466 unique users posted 3,368,258 vaccine-related tweets in Arabic. Topic modeling generated 25 topics, which were mapped to the 15 factors of the 5C model and HBM. Among the users, 32.87%were male, and 18.06% were female. A significant 55.77% of the users were from the MENA (Middle East and North Africa) region. Twitter users were more inclined to accept vaccines when they trusted vaccine safety and effectiveness, but vaccine hesitancy increased due to conspiracy theories and misinformation. The association of topics with these theoretical frameworks reveals the availability and diversity of Twitter data that can predict behavioral change toward vaccines. It allows the preparation of timely and effective interventions for vaccination programs compared to traditional methods.
The Phase Diagram of Crystalline Surfaces
Creators: name: Anagnostopoulos, K. N.
name: Bowick, M. J.
name: Catterall, S. M.
name: Falcioni, M.
name: Thorleifsson, G.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We report the status of a high-statistics Monte Carlo simulation of non-self-avoiding crystalline surfaces with extrinsic curvature on lattices of size up to $128^2$ nodes. We impose free boundary conditions. The free energy is a gaussian spring tethering potential together with a normal-normal bending energy. Particular emphasis is given to the behavior of the model in the cold phase where we measure the decay of the normal-normal correlation function.
description: 9 pages latex (epsf), 4 EPS figures, uuencoded and compressed. Contribution to Lattice '95
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 180 (11 H 755), 83 folios, f. 0114
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 180 (11 H 755), 83 folios, f. 0114, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 180 (11 H 755), 83 folios, f. 0114, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Status of the 0.8 Teraflops Supercomputer at Columbia
Creators: name: Arsenin, I.
name: Chen, D.
name: Christ, N.
name: Edwards, R.
name: Gara, A.
name: Hanson, S.
name: Jung, C.
name: Kahler, A.
name: Kennedy, A. D.
name: Kilcup, G.
name: Luo, Y.
name: Malureanu, C.
name: Mawhinney, R.
name: Parsons, J.
name: Sexton, J.
name: Sui, C.
name: Vranas, P.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The first stage in the construction of the 0.8 Teraflops Supercomputer at Columbia, a working, two node parallel computer, has been successfully completed. The next stage, a 512 node, 26 Gigaflops prototype, is in its final construction phase. A general description and current status of the hardware and software is presented.
description: 4 pages, uuencoded compressed Postscript file, contribution to Lattice 95
Constraining the Expansion History and Early Dark Energy with Line Intensity Mapping
Creators: name: Karkare, Kirit S.
name: Bird, Simeon
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We consider the potential for line intensity mapping (IM) experiments to measure the baryon acoustic oscillations (BAO) from 3 < z < 6. This would constrain the expansion history in a redshift range that is currently unexplored. We calculate the map depths that future IM experiments targeting the CO(1-0) rotational transition line and [CII] ionized carbon fine-structure line would need to achieve in order to measure the BAO. We find that near-future IM experiments could constrain the BAO scale to 5% or better depending on CO/[CII] model amplitude. This measurement is at a precision that could make competitive constraints on models of early dark energy.
description: 9 pages, 3 figures. Updated to reflect published version
The role of microRNA-515-5p in breast cancer
Creators: name: Pinho, Filipa Gomes
Publisher: name: Imperial College London
Year: 2014

description: MicroRNAs are a class of small non-coding RNAs which modulate a wide range of physiological and pathological processes by negatively regulating gene expression at the post-transcriptional level. MicroRNAs have been found to be important modulators of the tumorigenesis and metastasis formation of different human cancers, including breast cancer. Here we prove that miR-515-5p belongs to a particular subset of microRNAs which mediate estradiol (E2) action in the carcinogenesis of estrogen receptor-positive breast cancers, in which proliferation is highly dependent on E2. We show that miR-515-5p downregulation is the main responsible for the positive effect of E2 in the expression of SK1, an oncogenic enzyme required for E2-dependent breast cancer tumorigenesis. Upon E2 stimulation, estrogen receptor α (ERα) directly represses the transcription of miR-515-5p which leads to the upregulation of SK1 expression as a result of its reduced availability to target SK1. By conducting the first functional studies of miR-515-5p, here we also demonstrate that miR-515-5p plays a tumour suppressive role in breast cancer. miR-515-5p was found to inhibit breast cancer proliferation by inducing caspase-dependent apoptosis via SK1 and to repress breast cancer cell motility mainly by targeting MARK4, an enzyme implicated in the regulation of cell cytoskeleton dynamics. Overall, we identify a new signaling pathway involving ERα, SK1 and miR-515-5p and a new role for miR-515-5p which highlights its therapeutic potential for the treatment of breast cancer.
Additional file 1 of HLA-A2.1-restricted ECM1-derived epitope LA through DC cross-activation priming CD8+ T and NK cells: a novel therapeutic tumour vaccine
Creators: name: Yu, Zhaojin
name: Liu, Wensi
name: He, Ying
name: Sun, Mingli
name: Yu, Jiankun
name: Jiao, Xue
name: Han, Qiang
name: Tang, Haichao
name: Zhang, Bing
name: Xian, Yunkai
name: Qi, Jing
name: Gong, Jing
name: Xin, Wang
name: Shi, Gang
name: Shan, Fengping
name: Zhang, Rui
name: Li, Jianping
name: Wei, Minjie
Publisher: name: figshare
Year: 2021
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Figure S1. Quality confirmation of the peptides. Figure S2. Elevated expression of ECM1 in multiple tumours. Figure S3. Cytotoxicity of YL/DC-CTLs, LA/DC-CTLs, or LA/DC-NK cells against tumour cell lines. Figure S4. Cytotoxicity of YL/DC-CTLs, LA/DC-CTLs, or LA/DC-NK cells against primary tumour cells from HLA-A2.1+/ECM1+ patients. Figure S5. No cytotoxicity of LA- or YL-induced DC-CTLs or DC-NK cells on immune cells. Figure S6. ECM1-LA/DCs induce the activation of NK cells through the TLR4-p38-MICA/B pathway. Figure S7. The frequency of CD4+ T cells in splenocytes (n=3). Figure S8. There was no significant antitumour effect in the LA alone- or YL alone-treated group. Figure S9. No significant difference was detected in pathological examination of vital organs in xenograft mouse model. Figure S10. The KIR3DS1-activating pathway is not involved in the activation of NK cells by LA-pulsed DCs. Table S1. HLA-A alleles of tumour (or epithelium) cell lines. Table S2. Significant association of ECM1 mRNA expression with the malignant phenotype of various tumours. Table S3. Significant association of ECM1 protein expression with the malignant phenotype of various tumours. Table S4. Routine blood indexes were examined in different immune groups of HLA-A2.1 transgenic mice. Table S5. Main organ indexes are evaluated in different groups of HLA-A2.1 transgenic mice. Supplementary materials and methods.
Halo Star Lithium Depletion
Creators: name: Pinsonneault, M. H.
name: Walker, T. P.
name: Steigman, G.
name: Narayanan, V. K.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The depletion of lithium during the pre-main sequence and main sequence phases of stellar evolution plays a crucial role in the comparison of the predictions of big bang nucleosynthesis with the abundances observed in halo stars. In the past a wide range of possible depletion factors, ranging from minimal in standard (non-rotating) stellar models to as much as an order of magnitude in models including rotational mixing have been suggested. Using recent progress in the study of the angular momentum evolution of low mass stars, which now permits the construction of theoretical models that reproduce the angular momentum evolution of low mass open cluster stars, along with the observed distribution of initial angular momenta inferred from stellar rotation data in young open clusters, we study lithium depletion in main sequence halo stars. We predict a well-defined, nearly flat (in T_eff) halo lithium plateau with modest scatter and a small population of outliers. We also examine the relative depletions of 6Li and 7Li finding that the dispersion in the plateau and the 6Li/7Li depletion ratio scale with the absolute 7Li depletion. Using observational data to bound the 7Li depletion in main sequence halo stars, we find a maximum depletion of 0.4 dex is set by the observed dispersion and the 6Li/7Li depletion ratio, and a minimum depletion of 0.2 dex is required by both the presence of highly overdepleted halo stars and consistency with the solar and open cluster 7Li data. The cosmological implications of these bounds on the primordial abundance of 7Li are discussed. (Abridged)
description: 39 pages LaTeX, 12 postscript figures; ApJ submitted
The continuum limit in the quenched approximation
Creators: name: Blum, C. Bernard T.
name: DeTar, C.
name: Gottlieb, Steven
name: Heller, Urs M.
name: Hetrick, J.
name: Rummukainen, K.
name: Sugar, R.
name: Toussaint, D.
name: Wingate, M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Previous work at $6/g^2=5.7$ with quenched staggered quarks is extended with new calculations at 5.85 and 6.15 on lattices up to $32^3\times 64$. These calculations allow a more detailed study of extrapolation in quark mass, finite volume and lattice spacing than has heretofore been possible. We discuss how closely the quenched spectrum approaches that of the real world.
description: 4 pages, uuencoded compressed PostScript, contribution to Lattice '95
Additional file 5: of Pathogenic functions of host microbiota
Creators: name: Rath, Silke
name: Rud, Tatjana
name: Karch, André
name: Pieper, Dietmar
name: Vital, Marius
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Metagenomic and metatranscriptomic analyses of genes encoding three pathofunctions, namely, the formation of (i) trimethylamine (cutCD, cntAB, grdH), (ii) the secondary bile acids lithocholic/deoxycholic acid (baiA-I) and (iii) hydrogen sulfide (dsrAB) in 78 healthy male adults sampled at four time points [53]. Top panels display pathofunction abundance (A) and expression (B) considering all samples. Results of individual taxa are shown in the panels below (C, D), where relative abundances, i.e., percentage of each taxon from total pathofunction abundance/expression data, are shown. Panels E and F display temporal variability of both levels where $ indicates significant higher variability (p
Monte Carlo studies of antiferromagnetic spin models in three dimensions
Creators: name: Alonso, J. L.
name: Tarancón, A.
name: Ballesteros, H. G.
name: Fernández, L. A.
name: Martín-Mayor, V.
name: Muñoz~Sudupe, A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study several antiferromagnetic formulations of the O(3) spin model in three dimensions by means of Monte Carlo simulations. We discuss about the vacua properties and analyze the phase transitions. Using Finite Size Scaling analysis we conclude that all phase transitions found are of first order
description: 4 pages, 2 Postscript figures. Contribution to Lattice '95
Theoretical approaches to the study of fundamental British values (FBV)
Creators: name: McDonnell, Jane Louise
Publisher: name: PRISM: Casting New Light on Learning, Theory and Practice
Year: 2021

description: This article explores some of the critical instruments available to researchers investigating civic nationalist policy and practice via a review of the theoretical approaches that have been brought to bear on one such instance of national education policy, i.e. ‘fundamental British values’ (FBV) in England. The article offers a review of some key theoretical perspectives that have been applied to the study of FBV before offering some reflection on additional theoretical resources that might extend and compliment the insights that these provide. Specifically, I argue that concepts and interventions from the theoretical literature described as ‘radical democracy’ might be of particular use in complementing and extending some of the analysis of FBV in the existing literature.
description: PRISM: Casting New Light on Learning, Theory and Practice, Early View
Additional file 4: of Pathogenic functions of host microbiota
Creators: name: Rath, Silke
name: Rud, Tatjana
name: Karch, André
name: Pieper, Dietmar
name: Vital, Marius
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: The number of genomes of major genera exhibiting individual pathofunctions is displayed, where the percentage of bacteria exhibiting the pathofunction of all members of that genus is given in brackets (Number Genomes (% of genus)). Correlations between pathofunction abundances affiliated with a genus and abundances of all members of respective genera (based on three house-keeping genes) are shown as well (CorrelationTaxonomy). The number of datasets displaying a correlation (p and q 0.35, n = 12) is given and Spearman’s rho (average ± standard deviation) is displayed in brackets. Datasets IV and VI were merged as they derived from one source and have overlapping samples in the healthy control groups. ND: not determined. (PDF 48 kb)
Emission of cosmic rays from Jupiter. Magnetospheres as Sources of Cosmic Rays
Creators: name: Pizzella, G.
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Measurements made recently with the PAMELA satellite have shown with good evidence that a fraction of the cosmic rays detected on Earth comes from Jupiter. This result draws attention to the idea that magnetospheres of astrophysical objects could contribute to the sources of cosmic rays. We discuss this conjecture on the basis of Earth installed instrumentation and of the measurements made with PAMELA. The experiments strongly favor the validity of the conjecture. In particular the PAMELA data show that the proton fluxes are larger when the Earth orbit intersects the lines of the interplanetary magnetic field connecting Jupiter with Earth. This effect shows up with more than ten standard deviations, difficult to explain without the idea that part of the cosmic ray protons comes directly from the Jupiter magnetosphere.
Modeling the ten-image lensed system B1933+503
Creators: name: Nair, S.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A gravitational lens model is presented for the newly discovered 10-image system B1933+503. The underlying object, revealed by modeling, is a triple radio source on the scale of a couple of hundred mas that is well-aligned along the line of sight with a foreground and somewhat flattened lensing galaxy, whose orientation and location match that of an observed galaxy, known to be at a redshift of 0.755. Uncertainties in the modeling are obtained by a Monte Carlo exercise. Observational tests of the lens model are proposed, and the time delays between various pairs of images are determined as the core of the source is known to be significantly variable. Future observations of the lens hold the key to using B1933+503 to constrain Hubble's Constant. Despite the absence of a source redshift, the system's utility as a probe of the lens galaxy's structure is unparalleled as it provides a surfeit of easily identifiable constraints for modeling the system.
description: 11 pages (accepted for publication by the MNRAS) (correction: footnote regarding Kassiola & Kovner (1993) deleted as unnecessary)
Oral history interview with William Fitzpatrick 1979
Publisher: name: Columbia University
Year: 2020
Subjects: Lawyers
Law--United States
Practice of law

description: Law School education; early years as trial lawyer in Syracuse; changes in meaning and practice of law, negligence law, human rights law (including Bakke decision), advertising, paralegals; quality of today's lawyers; professional responsibilities; advice to young lawyers
Phonon Coherence and Its Effect on Thermal Conductivity of Nanostructures
Creators: name: Xie, Guofeng
name: Ding, Ding
name: Zhang, Gang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The concept of coherence is one of the fundamental phenomena in electronics and optics. In addition to electron and photon, phonon, is another important energy and information carrier in nature. Without any doubt, exploration of the phonon coherence and its impact on thermal conduction will markedly change many aspects in broad applications for heat control and management in the real world. So far, the application of coherent effect on manipulation of phonon transport is a challenge work. In this article, we review recent advances in the study of the phonon coherent transport in nanomaterials and nanostructures. We first briefly look back the classical and quantum theory of coherence. Next, we review the progresses made in the understanding of phonon coherence in superlattice, nanowires and nanomeshes, respectively, focus on the effect of phonon coherence on thermal conductivity. Finally, we introduce the recent advances in the direct detection of phonon coherence using optical coherence theory.
Additional file 1 of The role of Sphingomyelin synthase 2 (SMS2) in platelet activation and its clinical significance
Creators: name: Guo, Yifan
name: Chang, Lin
name: Zhang, Ge
name: Gao, Zhanyan
name: Lin, Hao
name: Zhang, Yuting
name: Hu, Liang
name: Chen, She
name: Fan, Bing
name: Zhang, Si
name: Xue, Ruyi
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Fig. 1. SMS2 deficiency impaired integrin αIIbβ3 activation. (A) PCR detection of SMS2 expression in platelets from WT mice, SMS2 –/– mice, SH-SY5Y cell line, rats and human. (B-E) Flow cytometry analysis of CD41 (B, C) and CD61 (D, E) expression on WT and SMS2 –/– platelets surface membrane. Resting and thrombin (0.05 U/mL) stimulated platelets were incubated with specific fluorescent antibody and detected with a flow cytometer (BD FACSAria, IIF0893488) (n = 5, n.s. P > 0.05). (F-I) Jon/A and fibrinogen binding either at resting state or under the stimulation of thrombin (0.05 U/mL) with WT and SMS2 –/– platelets (n = 5, n.s. P > 0.05, * P < 0.05). Supplementary Fig. 2. SMS2 deficiency diminished ADP- and U46619-induced platelet aggregation. (A, B) WT and SMS2 –/– platelets were stimulated with ADP and U46619 at their indicated concentrations in a platelet aggregator at 1000 rpm for 37 ℃ (n = 4, n.s. P > 0.05, * P < 0.05, ** P < 0.01). (C, D) Aggregation of human platelets stimulated by ADP (10 µM) and U46619 (0.75 µM) in the presence of various concentrations of D609 (red curve, 100 µM, purple curve, 30 µM, gray curve, 10 µM, black curve, DMSO control, n = 4, * P < 0.05, ** P < 0.01, *** P < 0.001). Supplementary Fig. 3. The specificity of D609 on SMS2. (A) Aggregation of WT and SMS2 –/– platelets induced by ADP (10 µM), U46619 (0.75 µM), thrombin (0.075 U/mL), and collagen (1.2 µg/mL) in the presence or absence of D609 (10 µM). Results showed that D609 inhibited platelet aggregation in WT platelets, but had no significant effect on SMS2 –/– platelets. (B) Statistic results of platelet aggregation induced by indicated agonists (n = 4, n.s. P > 0.05, * P < 0.05, ** P < 0.01). Supplementary Fig. 4. (A) Representative images of SMS2 level and corresponding 0.05 U/mL thrombin-induced P-selectin exposure on platelet surface membrane from patients with ACS (black curve, SMS2 low expression, red curve, SMS2 high expression). (B) A positive correlation was found between SMS2 level and corresponding P-selectin exposure (n = 19, Pearson r = 0.5826, P [two-tailed] < 0.01, GraphPad Prism version 7).
Proyecto europeo W-STEM
Creators: name: García-Holgado, A.
Publisher: name: Zenodo
Year: 2019
Subjects: CBHE, EU, género, STEM, W-STEM

description: Presentación del Proyecto Europeo Building the future of Latin America: Engaging women into STEM (W-STEM – Ref. 598923-EPP-1-2018-1-ES-EPPKA2-CBHE-JP), financiado en el Programa Capacity-Building in Higher Education de la Unión Europea. Esta presentación se realizó el 25 de Agosto de 2019 en la Universidad Nacional San Agustín de Arequipa, Perú.

description: W-STEM (Building the future of Latin America: engaging women into STEM) is a project funded under European Union ERASMUS + Capacity-building in Higher Education Programme (598923-EPP-1-2018-1-ES-EPPKA2-CBHE-JP) The European Commission support for the production of this publication does not constitute an endorsement of the contents which reflects the views only of the authors, and the Commission cannot be held responsi­ble for any use which may be made of the information contained therein
Additional file 3: of Pathogenic functions of host microbiota
Creators: name: Rath, Silke
name: Rud, Tatjana
name: AndrĂŠ Karch
name: Pieper, Dietmar
name: Vital, Marius
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Neighbor joining tree of baiCD sequences. Sequences from C. sordellii were merged. On the right, taxonomic affiliations (on genus level) are given with amount of reads (as % of total bai associated reads) from omics data (nâ =â 2975) linked to individual taxa. &: Sequences derive from metagenomic species (including information on isolation source (host)). (PDF 58 kb)
Oral history interview with William Fowlkes, 1971
Publisher: name: Columbia University
Year: 2019
Subjects: Newspapers--Circulation
Advertising--Newspapers
Journalism--Social aspects
Editors
Journalists
African Americans--Civil rights
African American press
African American journalists

description: In this interview conducted by Henry G. La Brie III, William A. Fowlkes tells his life history and goes on to discuss the advertising and circulation changes in black newspapers, how black newspapers’ role has changed over time, and the successes and failures of the black press. He explains his criteria needed to consider a newspaper as a black newspaper, what readers want to read, and whether black news papers are sensational. Fowlkes discusses if the Kerner Commission Report affected white establishment papers’ reporting on minority news, if black news papers should appeal to a white audience, and the future of the black press.
Non-perturbative renormalization of the $ΔS=2$ operator and the heavy-light axial current
Creators: name: Donini, A.
name: Gimenez, V.
name: Martinelli, G.
name: Sachrajda, C. T.
name: Talevi, M.
name: Vladikas, A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We apply a recently introduced non-perturbative renormalization method to two types of lattice operators: the $ΔS=2$ four fermion operator and the heavy-light static axial current, which are relevant for the physics of $K$ and $B$ mesons respectively. The results of the non-perturbative calculations of the renormalization constants are compared with the corresponding perturbative ones.
description: LaTeX, 4 pages postscript uuencoded, contribution to Lattice 95
A 3rd Class of Gamma Ray Bursts?
Creators: name: Horvath, I.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Two classes of Gamma Ray Bursts have been identified so far, characterized by T_90 durations shorter and longer than approximately 2 seconds. We show here that the BATSE 3B data allow a good fit with three Gaussian distributions in log T_90. The chi^2 statistic indicates a 40 % probability for two Gaussians, whereas the three-Gaussian fit probability is 98 %. Using another statistical method, it is argued that the probability that the third class is a random fluctuation is less than 0.02 %.
description: 10 pages, 5 Postscript figures. Submitted to The Astrophysical Journal, October 1997
FRnet-DTI: Deep Convolutional Neural Networks with Evolutionary and Structural Features for Drug-Target Interaction
Creators: name: Rayhan, Farshid
name: Ahmed, Sajid
name: Mousavian, Zaynab
name: Farid, Dewan Md
name: Shatabda, Swakkhar
Publisher: name: arXiv
Year: 2018
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The task of drug-target interaction prediction holds significant importance in pharmacology and therapeutic drug design. In this paper, we present FRnet-DTI, an auto encoder and a convolutional classifier for feature manipulation and drug target interaction prediction. Two convolutional neural neworks are proposed where one model is used for feature manipulation and the other one for classification. Using the first method FRnet-1, we generate 4096 features for each of the instances in each of the datasets and use the second method, FRnet-2, to identify interaction probability employing those features. We have tested our method on four gold standard datasets exhaustively used by other researchers. Experimental results shows that our method significantly improves over the state-of-the-art method on three of the four drug-target interaction gold standard datasets on both area under curve for Receiver Operating Characteristic(auROC) and area under Precision Recall curve(auPR) metric. We also introduce twenty new potential drug-target pairs for interaction based on high prediction scores. Codes Available: https: // github. com/ farshidrayhanuiu/ FRnet-DTI/ Web Implementation: http: // farshidrayhan. pythonanywhere. com/ FRnet-DTI/
Characterizations of Colletotrichum spp., Pathogens on Mango Fruits (Mangifera indica L. cv. 'Nam Dok Mai')
Creators: name: Sasivimol Laksanaphisut
name: Pattavipha Songkumarn
name: Somsiri Sangchote
Publisher: name: Department of Agriculture
Year: 2019
Subjects: Colletotrichum gloeosporioide
C. acutatum
anthracnose
mango

description: Thai Agricultural Research Journal, 37, 2, 197-215
Variants of Lüscher's fermion algorithm
Creators: name: Boriçi, Artan
name: de Forcrand, Philippe
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study improved variants of Lüscher's algorithm, including the cases of staggered fermions and finite density.
description: 4 uuencoded PostScript pages, contribution to LAT95 (fig.1 removed to conserve space; available upon request)
Additional file 2: of Pathogenic functions of host microbiota
Creators: name: Rath, Silke
name: Rud, Tatjana
name: AndrĂŠ Karch
name: Pieper, Dietmar
name: Vital, Marius
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Area under the receiver-operating characteristic curve (AUC) applying generalized linear mixed-effects models for each disease based on abundances of genes encoding three pathofunctions, namely, the formation of (i) trimethylamine (TMA: cutCD, cntAB and grdH), (ii) the secondary bile acids lithocholic/deoxycholic acid (bai operon) and (iii) hydrogen sulfide (dsr genes) are displayed as well as results from combined data (All). AUCs of individual datasets and of diseases represented by only one dataset based on logistic regression are indicated after arrows on the right and at the bottom, respectively. Data encompassed patients suffering from cardiovascular disease (CVD: I, II), type 2 diabetes (T2D: III-V), obesity (Obese: VI), colorectal cancer (CRC: VII, VIII, IX), liver cirrhosis (Cirr: X) and inflammatory bowel disease (IBD: ulcerative colitis (UC) and Crohnâ s disease (CD), XI and XII). Samples from type 1 diabetes (dataset IV), adenomas (datasets VII and VIII) and CD of dataset XI were not considered. For details on individual datasets see TableÂ 2. (PDF 2400 kb)
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Cart. 192 (11 H 77), 295 folios, f. 0241r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0241r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0241r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
A Geometrical Relationship between Broad-Line Clouds and an Accretion Disk around Active Galactic Nuclei
Creators: name: Nishiura, S.
name: Murayama, T.
name: Taniguchi, Y.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Recent hard X-ray spectroscopy of active galactic nuclei has strongly suggested that double-peaked, very broad Fe K emission arises from an accretion disk around the central engine. Model fitting of the observed Fe K emission line profile makes it possible to estimate a probable inclination angle of the accretion disk. In order to study the geometrical relationship between the accretion disk and broad emission-line regions (BLRs), we investigate the correlation between the inclination angle of the accretion disk and the velocity width of BLRs for 18 type-1 Seyfert galaxies. We found that there may be a negative correlation between them, i.e., Seyfert nuclei with a more face-on accretion disk tend to have larger BLR velocity widths, suggesting that the BLRs are not coplanar with respect to the accretion disk. The most probable interpretation may be that the BLRs arise from outer parts ({\it r} $\sim$ 0.01 pc) of a warped accretion disk illuminated by the central engine.
description: 11 pages, 3 figures; accepted for Publications of the Astronomical Society of Japan
Topological susceptibility and Instanton size distribution from over-improved cooling
Creators: name: de Forcrand, Philippe
name: Kim, Seyong
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We measure the topological susceptibility by cooling with an over-improved action. In contrast with usual cooling, large instantons survive over-improved cooling {\em indefinitely}. By varying the parameter of the over-improved cooling action, we measure the instanton size distribution.
description: 4 uuencoded PostScript pages, contribution to LAT95 (fig.2 simplified to conserve space; available upon request)
Exotic dynamical evolution in a secant-pulse driven quantum system
Creators: name: Zhao, Peng-Ju
name: Li, Wei
name: Cao, Hong
name: Yao, Shao-Wu
name: Cen, Li-Xiang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate an explicitly time-dependent quantum system driven by a secant-pulse external field. By solving the Schrödinger equation exactly, we elucidate exotic properties of the system with respect to its dynamical evolution: on the one hand, the system is shown to be essentially nonadiabatic, which prohibits an adiabatic approximation for its dynamics; on the other hand, the loop evolution of the model can induce a geometric phase which, analogous to the Berry phase of the cyclic adiabatic evolution, is in direct proportion to the solid angle subtended by the path of the state vector. Moreover, we extend the model and show that the described properties coincide in a special family of secant-pulse-driven models.
description: 5 pages, 3 figures
Durability of immune response against omicron BA.2 and BA.4/5 and T cell responses after boosting with mRNA and adenoviral vector-based vaccines following heterologous CoronaVac/ChAdOx-1nCov-19 vaccination
Creators: name: Suntronwong, Nungruthai
name: Kanokudom, Sitthichai
name: Thatsanathorn, Thaksaporn
name: Thongmee, Thanunrat
name: Sudhinaraset, Natthinee
name: Wanlapakorn, Nasamon
name: Poovorawan, Yong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Heterologous vaccination with inactivated vaccine followed by adenoviral vector-based vaccine has shown superiority in enhancing immune response compared to homologous primary series. However, data comparing immunity decline after a third booster following heterologous CoronaVac/ChAdOx-1nCov-19 has been limited. Here, we assessed neutralizing activity against omicron variant and T cell response at 3 months monitoring in 96 individuals who received ChAdOx-1nCov-19, BNT162b2, or mRNA-1273 as a third dose following heterologous CoronaVac/ChAdOx-1nCov-19. Comparing the antibody levels at 3 and 1 month(s) after the third booster, the results showed a persistence of anti-RBD IgG in all vaccine regimens, with the IgG level waning slower in the ChAdOx-1nCov-19 boosted group (geometric mean ratio (GMR): 0.64 (95%CI: 0.59–0.70)) compared to the BNT162b2 (0.34 (95%CI:0.31–0.38)) and mRNA-1273 boosted groups (0.32 (95%CI: 0.29–0.36)). Neutralizing activity against omicron BA.2 and BA.4/5 dropped by 1.2 to 1.5-fold but remained detectable, with the highest level observed in the mRNA-1273 group, followed by BNT162b2 and ChAdOx-1nCov-19 groups, respectively. Furthermore, the number of individuals with T cell reactivity decreased in BNT162b2 and mRNA-1273 groups, while it increased in ChAdOx-1nCov-19 group at 3-month post-boost compared to 1 month. Data on the durability of immune response could help comprehensively optimize the booster vaccine strategy.
Additional file 1: of Pathogenic functions of host microbiota
Creators: name: Rath, Silke
name: Rud, Tatjana
name: Karch, André
name: Pieper, Dietmar
name: Vital, Marius
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Indications in original studies for differential abundance of the three pathofunctions, namely, the formation of trimethylamine (TMA), secondary bile acids lithocholic/deoxycholic acid (LCA/DCA) and hydrogen sulfide (H2S) between patients and respective controls based on functional and taxonomy-based analyses. Data was queried for functions based on function names and KEGG Orthologies (provided for most studies. CutC/D: K20038/K20038, cntA/B: K22443/ K22444, grdH: K21579, baiCD/E: K15870/K15872, dsrA/B: K11180/ K11180). Taxonomic data was screened for key taxa that correlated with function based on information given in Additional file 4 (TMA (cntAB): Escherichia/Klebsiella, TMA (grdH): Dorea, H2S: Bilophila/Desulfovibrio). Clostridium scindens (DCA/LCA) was included as well. Jie et al. [21] (dataset I) additionally analyzed datasets III, VI and X for TMA associated genes based on selected reference sequences and results are also displayed. Forslund et al. [24] included studies III-V into their analysis and reported a trended increase (p = 0.07) for MF0100 (dissimilatory sulfate reduction) in T2D patients across studies. ?: no information on that function/taxa was retrieved, =: no difference between patients and control group, CD: Crohn’s disease, CRC: colorectal cancer, CVD: cardiovascular disease, HGC: high gene count group, MLG: metagenomic linkage group, T2D: type 2 diabetes, UC: ulcerative colitis. (PDF 56 kb)
Additional file 1 of Phagocytosis of polymeric nanoparticles aided activation of macrophages to increase atherosclerotic plaques in ApoE−/− mice
Creators: name: Yin, Tieying
name: Li, Yanhong
name: Ren, Yuzhen
name: Fuad, Atik Rohmana Maftuhatul
name: Hu, Fangfang
name: Du, Ruolin
name: Wang, Yang
name: Wang, Guixue
name: Wang, Yazhou
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Hematology

description: Additional file 1: Fig. S1. SDS-PAGE Characterization of protein coronae formed on the surface of PLGA NPs exposed to serum. Lane 1: standard molecular marker, Lane 2: 10 μg PLGA + PC, Lane 3: 10 μg PLGA NPs, Lane 4: supernate after three cycles of washing and centrifugation for 10 μg PLGA + PC. Fig. S2. H&E staining of main organs after PLGA NPs injection for 4 and 12 weeks. There were no obvious changes between each group.
Revised Gaia Data Release 2 passbands
Creators: name: Weiler, Michael
Publisher: name: arXiv
Year: 2018
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The European Space Agency mission Gaia has published with its second data release (DR2) a catalogue of photometric measurements for more than 1.3 billion astronomical objects in three passbands. The precision of the measurements in these passbands, denoted G, G_BP, and G_RP, reaches down to the milli-magnitude level. The scientific exploitation of this data set requires precise knowledge on the response curves of the three passbands. This work aims to improve the exploitation of the photometric data by deriving an improved set of response curves for the three passbands, allowing for an accurate computation of synthetic Gaia photometry. This is achieved by formulating the problem of passband determination in a functional analytic formalism, and linking the photometric measurements with four observational, one empirical and one theoretical spectral library. We present response curves for G, G_BP, and G_RP that differ from the previously published curves, and which provide a better agreement between synthetic Gaia photometry and Gaia observations.
description: Accepted version