cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Tenthredo mesomela Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Tenthredinidae
Tenthredo
Tenthredo mesomela

description: Tenthredo mesomela [spec. nov.]
T. antennis septemnodiis, abdomine subflavo: dorso nigro arcubus flavescentibus. Fn. svec. 936.
Habitat in Europa.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 557, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Additional file 1: of Comorbidities and the referral pathway to access joint replacement surgery: an exploratory qualitative study
Creators: name: BĂŠlĂ¨Ne Podmore
name: Hutchings, Andrew
name: Mary-Alison Durand
name: Robson, John
name: Sujith Konan
name: Meulen, Jan Van Der
name: Lynch, Rebecca
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Topic guides. The topic guides for the semi-structured interviews with each group of healthcare professionals: Orthopaedic Surgeons, GPs and Intermediate care professionals. (DOCX 23 kb)
Mirror Symmetry and the Type II String
Creators: name: Morrison, David R.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: If $X$ and $Y$ are a mirror pair of Calabi--Yau threefolds, mirror symmetry should extend to an isomorphism between the type IIA string theory compactified on $X$ and the type IIB string theory compactified on $Y$, with all nonperturbative effects included. We study the implications which this proposal has for the structure of the semiclassical moduli spaces of the compactified type II theories. For the type IIB theory, the form taken by discrete shifts in the Ramond-Ramond scalars exhibits an unexpected dependence on the $B$-field. (Based on a talk at the Trieste Workshop on S-Duality and Mirror Symmetry.)
description: 8 pages, LaTeX using espcrc2.sty
Renormalization of generalized vector field models in curved spacetime
Creators: name: Ruf, Michael S.
name: Steinwachs, Christian F.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We calculate the one-loop divergences for different vector field models in curved spacetime. We introduce a classification scheme based on their degeneracy structure, which encompasses the well-known models of the non-degenerate vector field, the Abelian gauge field and the Proca field. The renormalization of the generalized Proca model, which has important applications in cosmology, is more complicated. By extending standard heat-kernel techniques, we derive a closed form expression for the one-loop divergences of the generalized Proca model.
description: 24 pages, one figure, typos corrected, accepted for publication in Phys. Rev. D
Is a classical description of stable non-BPS D-branes possible?
Creators: name: Bertolini, M.
name: Di Vecchia, P.
name: Frau, M.
name: Lerda, A.
name: Marotta, R.
name: Russo, R.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the classical geometry produced by a stack of stable (i.e. tachyon free) non-BPS D-branes present in K3 compactifications of type II string theory. This classical representation is derived by solving the equations of motion describing the low-energy dynamics of the supergravity fields which couple to the non-BPS state. Differently from what expected, this configuration displays a singular behaviour: the space-time geometry has a repulson-like singularity. This fact suggests that the simplest setting, namely a set of coinciding non-interacting D-branes, is not acceptable. We finally discuss the possible existence of other acceptable configurations corresponding to more complicated bound states of these non-BPS branes.
description: Latex file: 41 pages, 5 figures; some minor corrections and references added
Regulatory T cell control of immune responses during acute Streptococcus pyogenes infection
Creators: name: Chong, Deborah Lai Wah
Publisher: name: Imperial College London
Year: 2012

description: Streptococcus pyogenes, also known as Group A Streptococci (GAS) causes many diseases, ranging from non-invasive (“Strep throat) to highly invasive (bacterial sepsis). GAS secretes various virulence factors implicated in pathogenesis and immune evasion, the best studied include superantigens. Regulatory T cells (Tregs) are a subset of CD4+ T cells, previously described in maintaining the fine balance of immune responses during infectious diseases; however, the precise role during streptococcal infection is unknown. The work in this thesis involves the characterisation of Tregs in the pathogenesis of GAS infection. Depletion of Tregs in inducible Foxp3.DTR knockout mice during GAS infection showed significant reduction in systemic bacterial spread and decreased serum levels of proinflammatory cytokines (IL-6 and IFN-γ), suggesting Tregs are detrimental to the host response to this bacterium. Further examination of effector cells indicate a protective role for CD8+, γδ+ T cells and NK cells in this model of acute sepsis as depletion of either of these subsets exacerbated bacterial burden and altered cytokine production. Utilising a transgenic HLA-DQ8.Aβ0 murine model, previously demonstrated to be susceptible to streptococcal superantigens, up-regulation of Foxp3 gene and protein expression in secondary lymphoid tissues during early stages of infection was attributed to the presence of SMEZ superantigen, correlating with decreased bacterial load. SPEA superantigen was found to induce TH1 cells and enhanced IFN-γ production to lead to the so-called “cytokine storm” and increased bacterial burden. This suggests that GAS through the action of secreted superantigens, modulates the immune response to induce Tregs and establish a state of tolerance to hinder protective effector cells, such as CD8+, γδ+ T cells and NK cells and IL-17A production, while promoting pathogenic TH1 cells to drive potent immune pathology.
$S$-Duality and the Calabi-Yau Interpretation of the $N = 4$ to $N = 2$ Flow
Creators: name: Gomez, C.
name: Hernandez, R.
name: Lopez, E.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The action of the $S$-duality $Sl(2,Z)$ group on the moduli of the Calabi-Yau manifold $W\IP^{12}_{11226}$ appearing in the rank two dual pair $(K^{3}\times T^{2}/W\IP^{12}_{11226})$ is defined by interpreting the $N\!=\!4$ to $N\!=\!2$ flow, for $SU(2)$ supersymmetric Yang-Mills, in terms of the Calabi-Yau moduli. The different singularity loci are mapped in a one to one way, and the ($N\!=\!2$ limit/point particle limit) is obtained in both cases by the same type of blow up. Moreover, it is shown that the $S$-duality group permutes the different singularity loci of the moduli of $W\IP^{12}_{11226}$. We study the transformation under $S$-duality of the Calabi-Yau Yukawa couplings.
description: 14 pages, Latex, 2 eps files. Comments, one more figure and references added
Additional file 2: of Effect of an audience on trainee stress and performance during simulated neonatal intubation: a randomized crossover trial
Creators: name: Bensouda, Brahim
name: Mandel, Romain
name: Abdelwaheb Mejri
name: Lachapelle, Jean
name: St-Hilaire, Marie
name: Ali, Nabeel
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Statistical analysis. Analysis of categorical and continuous variables by condition and sequence (DOCX 17 kb)
Oral history interview with Nicholina, 1980
Publisher: name: Columbia University
Year: 2020
Subjects: Drug addicts--United States
Imprisonment--United States
Drug traffic--History--20th century.--United States
Drug abuse--History--20th century.--United States
Opium abuse--History--20th century.--United States
Heroin abuse--History--20th century.--United States
Drug addicts--Rehabilitation--United States
Methadone maintenance--History--20th century.--United States
Prostitution--History--20th century.--United States
Crime--New York (State)

description: In this interview, Nicholina discusses her life in New York City, focusing on her drug use. She discusses moving to New York City from her hometown of Newark, New Jersey at the age of seventeen, and how she immediately became involved in sex work. She describes the circumstances of her first use of opium at eighteen years of age. She describes how the drug trade changed when control switched from Jewish crime syndicates to Italian mafia in the early 1930s. She compares opium users to heroin users, and discusses popular attitudes ascribed to both groups. Describes her enjoyment of "lay-down joints," or rooms in hotels dedicated to opium smoking where patrons could pay five dollars to smoke. She describes the broad array of people that would visit these joints using metrics of class, race, and occupation. Nicholina describes a period of opium scarcity, during World War II, and her transition to using opium in other forms like yen-shee and yen-pox, as well as other drugs like paregoric, morphine, Dilaudid, and heroin. She discusses her arrest history and time she spent incarcerated. Facilities included: Bedford Hills Correctional Facility and Women's House of Detention. She describes how she smuggled heroin into Bedford Hills Correctional Facility. She describes her various methods of earning money including shoplifting and drug dealing. Nicholina explains how the quality of heroin deteriorated from the 1930s to the 1960s. She describes how she joined a methadone program in 1970, and stopped taking all other drugs
RESISTÊNCIA INTELECTUAL E SUBJETIVA: ATUAÇÃO DO GRUPO DE ESTUDOS "IGUALDADE ÉTNICO-RACIAL E EDUCAÇÃO" EM CONTEXTO UNIVERSITÁRIO
Creators: name: Pereira, Ana Lúcia
name: Amaral, Gustavo Ferreira
Publisher: name: Zenodo
Year: 2021
Subjects: Resistência Intelectual e Subjetiva
Decolonialidade
IGUALDADE ÉTNICO-RACIAL
EDUCAÇÃO

description: O artigo se constitui em relato de experiência sobre uma das ações do Projeto de Pesquisa e Extensão “Igualdade ÉtnicoRacial e Educação”, que está inscrito no Curso de Direito da Universidade Federal do Tocantins – UFT. A narrativa abarca os efeitos da participação de alunos e alunas negras nas reuniões quinzenas do grupo de estudos que se dedica ao conhecimento de autores e autoras negras, na perspectiva do pensamento de(s)colonial. A existência do grupo de estudos se justifica pela necessidade de criação de espaços alternativos na universidade, para o acolhimento e cura da dor causada pelo racismo cotidiano, acirrado no processo de implementação das políticas de ações afirmativas. O texto problematiza as práticas educativas formais e informais e ressalta a resistência teórica/subjetiva do pensamento negro marginal em contexto universitário. A reflexão está fundamentada no arcabouço teórico/metodológico de Grada Kilomba (2019). Parte da reflexão sobre ancestralidade e educação; aborda a as ações do grupo de estudos que são refletidas na vida e na saúde dos participantes e relaciona teoria e prática na perspectiva de(s)colonial e conclui que o do Projeto de Pesquisa e Extensão “Igualdade Étnico-Racial e Educação” é expressão de uma prática educacional de(s)colonial, no espaço da Universidade Federal do Tocantins.
Tenthredo rufipes Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Tenthredinidae
Tenthredo
Tenthredo rufipes

description: Tenthredo rufipes [spec. nov.]
T. antennis septemnodiis, corpore nigro, abdomine cingulis duobus luteis, pedibus rubris.
Habitat in Europa.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 557, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Lyman-$α$ forest constraints on interacting dark sectors
Creators: name: Garny, Mathias
name: Konstandin, Thomas
name: Sagunski, Laura
name: Tulin, Sean
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Lyman-$α$ forest is a valuable probe of dark matter models featuring a scale-dependent suppression of the power spectrum as compared to $Λ$CDM. In this work, we present a new estimator of the Lyman-$α$ flux power spectrum that does not rely on hydrodynamical simulations. Our framework is characterized by nuisance parameters that encapsulate the complex physics of the intergalactic medium and sensitivity to highly non-linear small-scale modes. After validating the approach based on high-resolution hydrodynamical simulations for $Λ$CDM, we derive conservative constraints on interacting dark matter models from BOSS Lyman-$α$ data on large scales, k<0.02(km/s)^(-1), with the relevant nuisance parameters left free in the model fit. The estimator yields lower bounds on the mass of cannibal dark matter, where freeze-out occurs through 3-to-2 annihilation, in the MeV range. Furthermore, we find that models of dark matter interacting with dark radiation, which have been argued to address the $H_0$ and $σ_8$ tensions, are compatible with BOSS Lyman-$α$ data.
description: 27 pages, 11 figures
The impact of cooling flows on the Tx-Lbol relation for the most luminous clusters
Creators: name: Allen, S. W.
name: Fabian, A. C.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We examine the effects of cooling flows on the T_X-L_Bol relation for a sample of the most X-ray luminous (L_Bol > 10^45 erg/s) clusters of galaxies known. Using high-quality ASCA X-ray spectra and ROSAT images we explicitly account for the effects of cooling flows on the X-ray properties of the clusters and show that this reduces the previously-noted dispersion in the T_X-L_Bol relationship. More importantly, the slope of the relationship is flattened from L_Bol \propto T_{X}^3 to approximately L_Bol\propto T_{X}^2, in agreement with recent theoretical models which include the effects of shocks and preheating on the X-ray gas. We find no evidence for evolution in the T_X-L_Bol relation within z~0.3. Our results demonstrate that the effects of cooling flows must be accounted for before cosmological parameters can be determined from X-ray observations of clusters. The results presented here should provide a reliable basis for modelling the T_X-L_Bol relation at high X-ray luminosities.
description: Submitted to MNRAS letters (December 1997). 6 pages, 4 figures in MNRAS LaTex style
Cooperative Bayesian Optimization for Imperfect Agents
Creators: name: Khoshvishkaie, Ali
name: Mikkola, Petrus
name: Murena, Pierre-Alexandre
name: Kaski, Samuel
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences

description: We introduce a cooperative Bayesian optimization problem for optimizing black-box functions of two variables where two agents choose together at which points to query the function but have only control over one variable each. This setting is inspired by human-AI teamwork, where an AI-assistant helps its human user solve a problem, in this simplest case, collaborative optimization. We formulate the solution as sequential decision-making, where the agent we control models the user as a computationally rational agent with prior knowledge about the function. We show that strategic planning of the queries enables better identification of the global maximum of the function as long as the user avoids excessive exploration. This planning is made possible by using Bayes Adaptive Monte Carlo planning and by endowing the agent with a user model that accounts for conservative belief updates and exploratory sampling of the points to query.
Assembly and selectivity of asialoglycoprotein receptors
Creators: name: Quintero-Martinez, Adrian
Publisher: name: Imperial College London
Year: 2012

description: Two galactose-binding receptors, the hepatic asialoglycoprotein receptor (ASGPR) and the macrophage galactose lectin (MGL) have been investigated. The ASGPR is believed to function in glycoprotein clearance from serum while MGL is involved in recognition of pathogens and tumours and in signalling and immunomodulation. This work describes the analysis of the specificity, structure and organisation of both receptors in humans and the two MGLs in mice. The ligand-binding properties of the two subunits of the ASGPR as well as MGL have been separately tested in glycan array analysis. The results show that primary binding to ligands in the human ASGPR occurs via the ASGPR-1 subunit. MGLs have different specificities even though they are highly similar in sequence and the two mouse MGLs differ markedly from the single MGL in humans and in rats. One of the mouse MGLs has a similar specificity to ASGPR-1 that evolved independently. Hydrodynamic studies of ASGPR-1 revealed that it can form homo-oligomers and circular dichroism analysis of the neck fragment showed that it has a coiled-coil structure. Hetero-oligomer formation was monitored using a mutant version of ASGPR1 that allows purification of the complex using double-affinity chromatography on galactose and mannose. Hetero-oligomers containing both types of subunits are more stable than homo-oligomers. The results suggest a model that can account for the variable subunit stoichiometries observed by various investigators. Hydrodynamic studies and circular dichroism of MGL suggest that the extracellular domain of the human protein is an oligomer not as stable as previously thought, and that its neck is a coiled-coil structure. For both receptors, transmembrane and cytoplasmic domains as well as glycosylation may have a role in their stability. The ability of MGL to recognise pathogen glycans was demonstrated using Trichinella spiralis secretions. It was found that similar glycoproteins are bound by the human and mouse receptors.
title: Granulomatous myositis
title: Myosite granulomateuse
Creators: name: Ndao Awa Cheikh
Publisher: name: Revue Marocaine de Rhumatologie (RMR)
Year: 2020
Subjects: Myosite; Granulome; Sarcoïdose; Sénégal.

description: Sarcoidosis is a multisystem granulomatosis of unknown etiology. Its clinical presentation is polymorphic with predominance of pulmonary manifestations in particular Lofgrën syndrome (mediastinal lymphadenopathy, erythema nodosa and inflammatory polyarthralgia). Myositis is one of the rare or even atypical forms of sarcoidosis. This muscle damage can be revealing or occur during the course of sarcoidosis. Histology shows infiltration of the muscle by the epithelioid and giganto-cellular granuloma without caseous necrosis. We report the observation of a 42 year old lady received for bilateral proximal myogenic syndrome and symmetry whose histology is in favor of sarcoidosis myositis. The evolution was favorable under corticosteroid therapy.
description: La sarcoïdose est une granulomatose systémique d’étiologie inconnue. Sa présentation clinique est polymorphe avec prédominance des manifestations pulmonaires en particulier le syndrome de Lofgrën (adénopathies médiastinales, érythème noueux et polyarthralgie inflammatoire). La myosite fait par partie des formes rares voire atypiques de la sarcoïdose. Cette atteinte musculaire peut être révélatrice ou survenir au cours de l’évolution de la sarcoïdose. L’histologie montre une infiltration du muscle par le granulome épithélioïde et giganto-cellulaire sans nécrose caséeuse. Nous rapportons l’observation d’une dame de 42 ans reçue pour syndrome myogène proximal bilatéral et symétrie dont l’histologie est en faveur d’une myosite sarcoïdosique. L’évolution a été favorable sous corticothérapie.
Oral history interview with Nick J., 1980
Publisher: name: Columbia University
Year: 2020

description: In this interview, Nick J. discusses his life in New York City, focusing on his drug use. He describes using cocaine with a group of friends in his early teens. He discusses the etymology of the word "junkie" and its negative connotation. He discusses his time in the Navy during World War II, and how he was able to use morphine that was stashed in medical kits on the ship's lifeboats. He reviews his arrest history. He describes at length what he perceives to be the permanent effects of heroin on a user's brain, specifically brain fogginess. Nick describes attending shooting galleries, and what would happen when they were raided by the police, mentioning that he, a white man, was told to leave while Puerto Rican and Black patrons were arrested. He describes stealing from department and grocery stores, and selling the merchandise on the street. He explains how the quality of heroin plummeted in 1959, and how it was often mixed with Ajax, or crushed up aspirin and amphetamine pills. He discusses changes he has observed in the drug scene from the 1940s to the 1970s. He describes his experience detoxing from heroin at Beth Israel Hospitalin the early 1970s. He describes attending two private methadone programs
Continuous-discrete derivative-free extended Kalman filter based on Euler-Maruyama and Itô-Taylor discretizations: Conventional and square-root implementations
Creators: name: Kulikova, Maria V.
name: Kulikov, Gennady Yu.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Numerical Analysis (math.NA)
subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: In this paper, we continue to study the derivative-free extended Kalman filtering (DF-EKF) framework for state estimation of continuous-discrete nonlinear stochastic systems. Having considered the Euler-Maruyama and Itô-Taylor discretization schemes for solving stochastic differential equations, we derive the related filters' moment equations based on the derivative-free EKF principal. In contrast to the recently derived MATLAB-based continuous-discrete DF-EKF techniques, the novel DF-EKF methods preserve an information about the underlying stochastic process and provide the estimation procedure for a fixed number of iterates at the propagation steps. Additionally, the DF-EKF approach is particularly effective for working with stochastic systems with highly nonlinear and/or nondifferentiable drift and observation functions, but the price to be paid is its degraded numerical stability (to roundoff) compared to the standard EKF framework. To eliminate the mentioned pitfall of the derivative-free EKF methodology, we develop the conventional algorithms together with their stable square-root implementation methods. In contrast to the published DF-EKF results, the new square-root techniques are derived within both the Cholesky and singular value decompositions. A performance of the novel filters is demonstrated on a number of numerical tests including well- and ill-conditioned scenarios.
"Zombie" or active? An alternative explanation to the properties of star-forming galaxies at high redshift
Creators: name: Saturni, Francesco Gabriele
name: Mancini, Mattia
name: Pezzulli, Edwige
name: Tombesi, Francesco
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences
subject: Astrophysics of Galaxies (astro-ph.GA), Cosmology and Nongalactic Astrophysics (astro-ph.CO)

description: Star-forming galaxies at high redshift show anomalous values of infrared excess, which can be described only by extremizing the existing relations between the shape of their ultraviolet continuum emission and their infrared-to-ultraviolet luminosity ratio, or by constructing \textit{ad-hoc} models of star formation and dust distribution. We present an alternative explanation, based on unveiled AGN activity, to the existence of such galaxies. In fact, the presence of a weak AGN configures as a natural scenario in order to explain the observed spectral properties of such high-$z$ objects in terms of a continuum slope distribution rather than altered infrared excesses, due to the different shape of the AGN continuum emission with respect to quiescent galaxies. To this aim, we directly compare the infrared-to-ultraviolet properties of high-redshift galaxies to those of known categories of AGN (quasars and Seyferts). We also infer the characteristics of their possible X-ray emission. We find a strong similarity between the spectral shapes and luminosity ratios of AGN with the corresponding properties of such galaxies. In addition, we derive expected X-ray fluxes that are compatible with energetics from AGN activity. We conclude that a moderate AGN contribution to the UV emission of such high-$z$ objects is a valid alternative to explain their spectral properties. Even the presence of an active nucleus in each source would not violate the expected quasar statistics. Furthermore, we suggest that the observed similarities between anomalous star-forming galaxies and quasars may provide a benchmark for future theoretical and observational studies on the galaxy population in the early Universe.
description: 13 pages, 7 figures, 4 tables, accepted for publication in A&A
The role of oxidative and nitrative stress and histone de-acetylation in rhinovirus induced acute exacerbations of Chronic Obstructive Pulmonary Disease
Creators: name: Footitt, Joseph
Publisher: name: Imperial College London
Year: 2011

description: Acute exacerbations are the major cause of morbidity and mortality in COPD and respiratory virus infection is believed to be a leading aetiology. However mechanisms by which viruses induce acute exacerbations are poorly understood. This study reports the experimental inoculation with rhinovirus (RV) of COPD and non-obstructed smoking and non-smoking control subjects, of whom 9 COPD, 10 smoking and 11 non-smoking controls were later judged to have been successfully infected. The hypothesis tested was that RV infection led to the induction of oxidative and nitrative stress which resulted in degradation of histone deacetylase (HDAC) enzymes in COPD subjects but not controls. Subsequent histone hyperacetylation would then result in prolonged inflammatory gene transcription and therefore generate clinical features of an acute exacerbation. Following experimental RV inoculation the COPD subjects experienced excess lower respiratory tract symptoms and elevated virus load compared to the control groups. There was an associated acute inflammatory response and a greater burden of redox stress measured using the Griess and Potential of Antioxidant assays. HDAC2 activity was found to be reduced only in the COPD subjects following experimental RV infection. These findings would suggest that RV induced oxidative and nitrative stress results in reduced HDAC2 activity in COPD subjects leading to increased inflammation and symptoms consistent with the clinical phenotype of a COPD exacerbation.
title: ADCO, Cartulaire de Cîteaux pour les possessions de Dijon et du Dijonnais (XVe siècle), Cart. 175 (11 H 479), 115 folios, f. 0011
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour les possessions de Dijon et du Dijonnais (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 175 (11 H 479), 115 folios, f. 0011, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Dijon et du Dijonnais (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 175 (11 H 479), 115 folios, f. 0011, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
title: Characterisation of fluid-flow systems for Irish lead-zinc deposits
Creators: name: Lewis, Helen
Publisher: name: University of Glasgow
Year: 1995
Subjects: subject: Hydrothermal deposits, lead ores, zinc ores, Ireland.

description: The lead-zinc sulphide deposits of central Ireland are hosted primarily in Lower Carboniferous strata of the Midland Basin. The ores are thought to be approximately contemporaneous with their sedimentary hosts, but the mode of their formation is a subject of dispute. The mineralisation is variously regarded as having either a predominantly sedimentary-exhalative, or a predominantly MVT-type of genesis. The ores are hydrothermal, so the interpretation of mineral genesis is strongly linked to the interpretation of the fluid-flow system that generated the deposits. This thesis investigates the structural setting of the deposits, particularly in relation to faults, on both the regional and more local scales, and the nature of the fluid-flow systems that could have provided the mineralised fluids. The structural setting is established by reconstructing the geometry of the Midland Basin region, and restoring it to several stages in its Early Carboniferous development. The reconstruction and restorations identify a style of basin development dominated by the movement (mostly subsidence) of fault-bounded blocks of basement, with superjacent sedimentary rocks. The restorations reveal a spatial relationship between ore deposits and fault-block corners. This spatial relationship is proposed to have significance for exploration. The flow systems which could have been active in the Midland Basin and its surrounds (including the Munster Basin) are investigated using both mass balance, and numerical simulations of heat- and fluid-flow. The mass balance study shows that most of the suggested flow systems could have produced adequate metals, but tens to several thousand fluid pore-volumes are required to deliver these metals to the sites of deposition, thus eliminating compaction as a driving mechanism, and severely limiting the applicability of some of the other putative causes of fluid flow. When the results of the mass-balance and the numerical models are combined, they show that: regional flow systems could not have developed in central Ireland during the Carboniferous; gravity-driven flow is cold, shallow and only very local; but local convective systems that penetrate deep into the fractured basement not only develop in this setting, but are very stable. Convective circulation of hydrothermal fluids is the most likely cause of the Irish lead-zinc mineralisation.
Stochastic Analysis of Composite Materials
Creators: name: Whiteside, M. B.
Publisher: name: Imperial College London
Year: 2012

description: This thesis describes the development of stochastic analysis frameworks for use in engineering design and optimisation. The research focuses on fibre-reinforced composites, with the stochastic analyses of an existing analytical failure model for unidirectional composites and of a unit cell numerical model of a 2D 5-Harness satin weave. Stochastic failure envelopes are generated through parallelised Monte Carlo Simulation of deterministic, analytical, physically based failure criteria for unidirectional carbon fibre/epoxy matrix composite plies. Monte Carlo integration of global variance-based Sobol sensitivity indices is performed and utilised to decompose observed variance within stochastic failure envelopes into contributions from physical input parameters. It is observed how the interaction effect can be used to identify domains of bi-modal failure, within which the predicted failure probability is governed by multiple failure modes. A reduced unit cell (rUC) model of a 5-Harness satin weave is constructed and analysed deterministically in uniaxial and biaxial loading conditions. An algorithm is developed and implemented to fully automate the rUC construction such that stochastic variations of the crimp angle can be evaluated. Monte Carlo Simulation is employed to propagate the effect of the crimp angle through the deterministic model and the probabilistic response compared with data obtained experimentally. It is observed how simulated variability compares well in uni-axial compression, but under-predicts observed experimental variability in uni-axial tension. The influence of vertical stacking sequence of plies is also demonstrated through the study of in-phase and out-of-phase periodic boundary conditions. The research highlights various, potential advantages that stochastic methodologies offer over the traditional deterministic approach, making a case for their application in engineering design and providing a springboard for further research come the day when greater computational power is available.
The relationship between cooling flows and metallicity measurements for X-ray luminous clusters
Creators: name: Allen, S. W.
name: Fabian, A. C.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We explore the relationship between the metallicity of the intracluster gas in clusters of galaxies, determined by X-ray spectroscopy, and the presence of cooling flows. Using ASCA spectra and ROSAT images, we demonstrate a clear segregation between the metallicities of clusters with and without cooling flows. On average, cooling-flow clusters have an emission-weighted metallicity a factor ~ 1.8 times higher than that of non-cooling flow systems. We suggest this to be due to the presence of metallicity gradients in the cooling flow clusters, coupled with the sharply peaked X-ray surface brightness profiles of these systems. Non-cooling flow clusters have much flatter X-ray surface brightness distributions and are thought to have undergone recent merger events which may have mixed the central high-metallicity gas with the surrounding less metal-rich material. We find no evidence for evolution in the emission-weighted metallicities of clusters within z~0.3.
description: Submitted to MNRAS letters (December 1997). 6 pages, 2 figures in MNRAS LaTex style. Minor revisions
title: Bone infarction or Osteomyelitis ? Diagnostic difficulty in sickle cell disease
title: Infarctus osseux ou Ostéomyélite ? Difficulté diagnostique dans la drépanocytose.
Creators: name: Najlae El Ouardi
Publisher: name: Revue Marocaine de Rhumatologie (RMR)
Year: 2020
Subjects: Drépanocytose; Infarctus osseux; Ostéomyélite.

description: Introduction : Sickle cell disease is an autosomal recessive disorder of hemoglobin. Bone involvement, often represented by a bone infarction or osteomyelitis, is common in sickle cell disease. Despite their frequency, the differentiation between these two entities is a real diagnostic challenge. Cases report : We report here two cases. The first case is bone infarction of the right femur revealing sickle cell disease in a teenage of 17 years. The second case illustrates the diagnostic difficulty between bone infarction and osteomyelitis. A men of 30 years has a left femoro-tibial bone infarction treated initially as osteomyelitis. Conclusion : Bone infarction is a common complication in sickle cell disease. Its clinical, biological and radiological resemblance to osteomyelitis must be known for better management.
description: Introduction : La drépanocytose est une maladie autosomique récessive de l’hémoglobine. L’atteinte osseuse est fréquente, représentée souvent par un infarctus osseux ou une ostéomyélite. Malgré leur fréquence, la différenciation entre ces deux entités est un véritable chalenge diagnostique. Observation : nous rapportons ici 2 cas. Le 1er cas est un infarctus osseux du fémur droit révélant une drépanocytose chez un jeune de 17 ans. Le 2ème cas illustre la difficulté diagnostique entre un infarctus osseux et une ostéomyélite. Il s’agit d’un patient de 30 ans, connu drépanocytaire qui présente un infarctus osseux fémoro-tibial gauche traité initialement comme ostéomyélite. Conclusion : l’infarctus osseux est une complication courante de la drépanocytose. Sa ressemblance clinique, biologique et radiologique avec l’ostéomyélite doit être connue pour une meilleure prise en charge.
Oral history interview with Nick Salvatore, 2000
Publisher: name: Columbia University
Year: 2021
Subjects: Civil rights movements--History--20th century.--United States
Civil rights demonstrations--United States
Peace movements--History--20th century.--United States
Camps

description: Salvatore discusses his Catholic, working-class upbringing in Brooklyn, New York and its impact on his sociopolitical outlook. He describes the strength of his mother, a secretary responsible for three children after the sudden death of her husband in 1945, and his enrollment at Brooklyn Preparatory School. Salvatore describes working as a messenger on Wall Street and his fellow messengers, anarchists who first exposed him to radical politics. He describes his attendance of a 1963 sit-in at City Hall. Salvatore describes Brooklyn CORE and his work as a depot helper with the Teamsters from 1963 to 1965. In the next segment of the interview, Salvatore describes his involvement with Brooklyn CORE and the Harlem Parents Committee, which organized around the New York School Boycotts. He also recalls his co-founding of Patterson Camp, a summer camp in Bucks County, Pennsylvania for Harlem youth in the summer of 1965. Salvatore next focuses on his experience with the draft, antiwar organizing, and Students for a Democratic Society (SDS). He details his qualms with the tactics employed by SDS, and explains his decision to stop engaging with SDS after a demonstration in 1967. He discusses his time at University of California, Berkeley Graduate School and his advisor, Leon F. Litwack. He describes his writing and teaching career at Cornell University, as well as his travels in Mississippi, and teaching American history
Tenthredo campestris Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Tenthredinidae
Tenthredo
Tenthredo campestris

description: Tenthredo campestris [spec. nov.]
T. antennis septemnodiis, corpore nigro, abdominis cingulo flavo inaequali, pedibusque flavis.
Habitat in Europa.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 557, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
The role of H19/miR-675 in chondrocyte function Katarzyna Anna
Creators: name: Dudek, Katarzyna Anna
Publisher: name: Imperial College London
Year: 2012

description: Human articular cartilage is an avascular and aneural connective tissue covering the bone ends in the joints of the body. It functions in a hypoxic environment and cartilage cells, the chondrocytes, have adapted to use hypoxia to drive tissue-specific function. The maintenance of cartilage matrix homeostasis is an important topic in musculoskeletal research and is a subject of investigation in my laboratory. Previous work in the group has identified a non-coding RNA transcript (H19), which was highly expressed in human articular chondrocytes (to the levels of the most abundant matrix genes COL2A1 and AGC), and showed a pattern of expression strikingly similar to that of the known differentiated chondrocyte markers. Recently, H19 has been shown to give rise to a mature microRNA, namely miR-675. MicroRNAs have emerged as a new class of endogenous modulators of gene expression. Moreover, it was recently shown that microRNAs are essential for normal cartilage development in the mouse. Hence, the function of H19/miR-675 was investigated, in particular in terms of its importance in cartilage matrix gene regulation in normal, non-diseased, human articular chondrocytes. Overexpression of miR-675 increased type II collagen levels at the mRNA and secreted protein levels, whereas depletion of primary transcript H19 or inhibition of the mature microRNA (miR-675) caused a decrease in type II collagen message and protein levels. Finally, overexpression of miR-675 rescued type II collagen levels in H19-depleted or SOX9-depleted cells. Initial RNA interference experiments indicated that H19 is strongly regulated by the key cartilage transcription factor SOX9, as well as by another transcription factor important in chondrocytes, HIF-2α. These results were subsequently confirmed under endogenous conditions using chromatin immunoprecipitation assay (ChIP). The binding of these two transcription factors was found at specific sites downstream (SOX9) and upstream (HIF-2α) of the H19 transcription start site. Here we present a novel mechanism of COL2A1 regulation via miR-675 in human articular chondrocytes. We provide evidence that SOX9 directly targets H19, the primary transcript of miR- 675. This microRNA then positively regulates type II collagen in healthy human chondrocytes in an indirect manner. Additionally, HIF-2α directly binds both SOX9 and H19, thereby increasing levels of COL2A1 in hypoxia.
Effect of turbulent diffusion in modeling anaerobic digestion
Creators: name: Yan, Jeremy Z.
name: Kumar, Prashant
name: Rauch, Wolfgang
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Computer and information sciences

description: In this study, the impact of turbulent diffusion on mixing of biochemical reaction models is explored by implementing and validating different models. An original codebase called CHAD (Coupled Hydrodynamics and Anaerobic Digestion) is extended to incorporate turbulent diffusion and validate it against results from OpenFOAM with 2D Rayleigh-Taylor Instability and lid-driven cavity simulations. The models are then tested for the applications with Anaerobic Digestion - a widely used wastewater treatment method. The findings demonstrate that the implemented models accurately capture turbulent diffusion when provided with an accurate flow field. Specifically, a minor effect of chemical turbulent diffusion on biochemical reactions within the anaerobic digestion tank is observed, while thermal turbulent diffusion significantly influences mixing. By successfully implementing turbulent diffusion models in CHAD, its capabilities for more accurate anaerobic digestion simulations are enhanced, aiding in optimizing the design and operation of anaerobic digestion reactors in real-world wastewater treatment applications.
Dimensionality of excitons in stacked van der Waals materials: The example of hexagonal boron nitride
Creators: name: Aggoune, Wahib
name: Cocchi, Caterina
name: Nabok, Dmitrii
name: Rezouali, Karim
name: Belkhir, Mohamed Akli
name: Draxl, Claudia
Publisher: name: arXiv
Year: 2018
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: With the example of hexagonal boron nitride, we demonstrate how the character of electron-hole (e-h) pairs in van der Waals bound low-dimensional systems is driven by layer stacking. Four types of excitons appear, with either a two- or three-dimensional spatial extension. Electron and hole distributions are either overlapping or exhibit a charge-transfer nature. We discuss under which structural and symmetry conditions they appear and they are either dark or bright. This analysis provides the key elements to identify, predict, and possibly tailor the character of e-h pairs in van der Waals materials.
description: This version includes main text and the Supplemental Material wrapped in one file
Isometries in anti-de Sitter and Conformal Superspaces
Creators: name: Claus, P.
name: Rahmfeld, J.
name: Robins, H.
name: Tannenhauser, J.
name: Zunger, Y.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We derive explicit forms for the superisometries of a wide class of supercoset manifolds, including those with fermionic generators in the stability group. We apply the results to construct the action of SU(2,2|4) on three supercoset manifolds: (10|32)-dimensional AdS_5 x S^5 superspace, (4|16)-dimensional conformal superspace, and a novel (10|16)-dimensional conformal superspace. Using superembedding techniques, we show, to lowest non-trivial order in the fermions, that at the boundary of AdS_5, the superisometries of the AdS_5 x S^5$ superspace reduce to the standard N=4 superconformal transformations. In particular, half of the 32 fermionic coordinates decouple from the superisometries.
description: 19 pages, LaTeX
Counting gauge invariant operators in supersymmetric theories using Hilbert series
Creators: name: Torri, Giuseppe
Publisher: name: Imperial College London
Year: 2012

description: In this thesis, the problem of counting gauge invariant operators in certain supersymmetric theories is discussed. These objects have a very important role in supersymmetric gauge theories, since they can be used to describe the space of zero-energy solutions, called moduli space, of such theories. In order to approach the counting problem, a technique is used based on a function known in Algebraic Geometry as the Hilbert series. For the examined theories, this can be considered a a partition function counting gauge invariant operators in the field theory according to their charges under quantum global symmetries. In the first part of the thesis, particular focus will be given to the application of the Hilbert series to conformal Chern-Simons theories living on the world-volume of M2-branes probing different toric Calabi-Yau 4-fold singularities. It will be shown how the Hilbert series can be combined with the brane tiling formalism to characterise the mesonic moduli space of vacua of a given theory through its generators and the relations they satisfy. Then, toric duality for these theories will be presented, with special attention to the role played by Hilbert series in making such feature manifest between two or more theories. Finally, Chern-Simons theories living on M2-branes probing cones over smooth toric Fano 3-folds and their mesonic Hilbert series will be presented. In the second part, it will be shown how the Hilbert series can be applied to counting gauge invariant operators in supersymmetric generalisations of Quantum Chromodynamics, known as SQCD theories. The discussion will hinge on a specific class of theories, with N multiplets transforming in the fundamental and anti-fundamental and one in the adjoint representation of the gauge group. For each classical group, the Hilbert series of the moduli space will be used to determine the dimension on the spaces, their generators and to argue that they are all Calabi-Yau manifolds.
Additional file 1: of The effectiveness of high-intensity CBT and counselling alone and following low-intensity CBT: a reanalysis of the 2nd UK National Audit of Psychological Therapies data
Creators: name: Barkham, Michael
name: Saxon, David
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Biotechnology
Science Policy
Computational Biology

description: Multilevel model of PHQ-9 change using Markov chain Monte Carlo (MCMC). (DOCX 44 kb)