cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Role caveolin in tobacco use and nicotine signaling in traumatic brain injury
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Traumatic brain injury (TBI) annually affects 10 million people worldwide and is the leading cause of death or disability in industrialized countries. The changes to the brain as a result of brain trauma are worsened with tobacco use. Behavioral changes resulting from TBI and tobacco use consists of sensory and motor dysfunction, psychiatric and cognitive impairments all of which are attributed to biochemical, morphological and structural changes in the brain. Nicotine, the active ingredient in tobacco, stimulates a receptor in the brain known as the nicotinic acetylcholine receptor (nAChR). nAChR is found in neuronal cell membranes with the scaffold protein caveolin-1 (Cav-1). Molecular interactions between nAChRs and associated membrane proteins like Cav-1 are universally regarded as crucial mediators of neuronal function. In addition, nAChR and Cav-1 are active drug targets in medical treatment for abuse and addiction. We have previously shown that over-expressing Cav-1 specifically neuronal cells restores cellular membrane-localization of neurotransmitter receptors and improves learning and memory in older and TBI mice. Recent clinical findings on postmortem brains from professional athletes previously exposed to brain trauma (diagnosed with chronic traumatic encephalopathy or CTE) revealed decreased Cav-1 and nAChR expression in diseased neurons. Others have shown that TBI or chronic inhalation of electronic(e-) cigarette alters brain nAChR expression. Due to the growing epidemic from e-cigarette vaping abuse, elucidating the regulatory role of Cav-1 on nicotine-mediated nAChR signaling in individuals previously subjected to TBI may yield a better understanding on the comorbidity associated with TBI and tobacco use.
Supplemental material2 - Supplemental material for The Noise Exposure Structured Interview (NESI): An Instrument for the Comprehensive Estimation of Lifetime Noise Exposure
Creators: name: Guest, Hannah
name: Dewey, Rebecca S.
name: Plack, Christopher J.
name: Couth, Samuel
name: Prendergast, Garreth
name: Bakay, Warren
name: Hall, Deborah A.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental material2 for The Noise Exposure Structured Interview (NESI): An Instrument for the Comprehensive Estimation of Lifetime Noise Exposure by Hannah Guest, Rebecca S. Dewey, Christopher J. Plack, Samuel Couth, Garreth Prendergast, Warren Bakay and Deborah A. Hall in Trends in Hearing
Determining the carcinogenic potential of tobacco in pancreatic cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Pancreatic cancer will soon become the second leading cause of cancer-related death. Tumors in the pancreas are unique in that they are primarily composed of scar tissue that promotes the survival of the cancer cells. Exposure to carcinogens present in tobacco-related products has been demonstrated to increase risk for developing pancreatic cancer. While studies have demonstrated that exposure to components in tobacco products increases cancer in rodent models, it has been difficult to understand the molecular mechanisms by which these agents influence transformation in specific cell types. The advent of new three-dimensional organoid tissue culture modeling, the earliest stages of tumorigenesis can be evaluated. We propose to use these new 3D organoid cultures that we developed to model what happens to pancreatic cells following short- and long-term exposure to carcinogens present in tobacco and e-cigarette products. Using this approach, we will define the lowest concentrations at which these carcinogens induce malignant behavior both through mutagenesis of the DNA, generation of oxidant-related stress, and changing cell signaling. Given the importance of the scar tissue in promoting malignant behavior, we will also use organoids grown together with the scar tissue to assess how carcinogens change the communication between these cell types. Finally, we will test the true transformation potential of these carcinogens by re-introducing the organoids into mice and determining whether carcinogen exposure is sufficient for pancreatic tumorigenesis or if additional mutations are required. Overall, this proposal will define whether there are safe exposure limits for the pancreas, but more importantly establish whether the organoid model system is amenable to carcinogen studies. This will enable systematic investigation of exposure limits on a tissue-by-tissue basis, including the most common points of contact using lung, stomach, and skin organoids.
РОЛЬ ЛАТИНСКОГО ЯЗЫКА В ФАРМАЦИИ
Creators: name: Нурмаматова, Х.Ш.
name: Рахманова, А.А.
Publisher: name: Zenodo
Year: 2024

description: Латинский язык считается «мертвым» языком, но несмотря на это большое количество людей до сих пор им пользуются. А именно, этим древним языком, существующим уже более 3000 лет, пользуются медики, фармацевты, биологи и другие специалисты. Латинский язык получил своё название от племени латинов, которые жили в Италии, в местности Лаций, где в 753 году до н.э. был основан город Рим.
Dodecastichus dalmatinus
Creators: name: Colonnelli, Enzo
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Dodecastichus
Dodecastichus dalmatinus

description: Dodecastichus dalmatinus (Gyllenhal, 1834)
[= D. d. lauri (Stierlin, 1861), syn. nov.]. As already rightly established by Angelov (1975) ­ not agreed by Abbazzi & Osella (1992) and Abbazzi et al. (1995) ­ D. lauri falls within the range of variation D. dalmatinus (Magnano, hoc opus).
description: Published as part of Colonnelli, Enzo, 2003, A revised checklist of Italian Curculionoidea (Coleoptera), pp. 1-142 in Zootaxa 337 (1) on page 9, DOI: 10.11646/zootaxa.337.1.1, http://zenodo.org/record/5019737
Dodecastichus mastix
Creators: name: Colonnelli, Enzo
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Dodecastichus
Dodecastichus mastix

description: Dodecastichus mastix (Olivier, 1807)
[= D. m. perlongus (Solari & Solari, 1915), syn. nov.; = D. m. scabrior (Reitter, 1913), syn. nov.]. No subspecific rank, as already stated by Angelov (1975), can be given to the several forms of such a variable species (Magnano, hoc opus).
description: Published as part of Colonnelli, Enzo, 2003, A revised checklist of Italian Curculionoidea (Coleoptera), pp. 1-142 in Zootaxa 337 (1) on page 9, DOI: 10.11646/zootaxa.337.1.1, http://zenodo.org/record/5019737
Tribal Community-Involved Commercial Tobacco Reduction: Peer Support Beyond the Clinic
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Building upon preliminary data from 15 years of collaboration between the teams of Co-PIs Drs. Calac and Moore, including the currently funded TRDRP T30IR0933, “Multilevel prevention of commercial tobacco-related harms on rural California Tribal lands,” we propose an expansion of a multi-pronged intervention that aims to reduce young California Indian exposure to and use of commercial tobacco through environmental interventions and systems changes that will bolster cessation efforts for adults, thereby removing physical and social availability of commercial tobacco products for youth. The prevalence of commercial tobacco use in this population is higher than among other Californians’ average use. The Community Partner Co-PI is Daniel Calac, MD, who is an enrolled member of the local Pauma Tribe as well as Chief Medical Officer of Indian Health Council. Dr. Calac observes that commercial tobacco and cardiovascular disease are the Achilles heel of American Indians and Alaska Natives, particularly overlapping with diabetes and behavioral health problems in the population. He and his colleagues have worked closely with Academic Co-PI Roland Moore, Ph.D. and PIRE California coworkers on multi-level substance use prevention projects, funded by NIAAA, NIDA, and TRDRP. The proposed study combines extending cessation resources to rural reservation communities accompanied by reward and reminder programs to limit the sale of electronic cigarette supplies and other commercial tobacco products to American Indian youth under the age of 21. To assure the necessary community oversight for the project, the study will be guided by the Tribal IRB, the clinic’s Scientific Advisory Board consisting of two representatives from each of nine consortium tribes, and the Southern California Tribal Tobacco Consortium from four of those tribes, which will serve as the Community Advisory Board. Outcome measures concerning commercial tobacco use and cessation from the clinic’s electronic health records will be triangulated with survey and qualitative data to assess the success of the proposed program’s components as well as their synergistic impact overall. Sharing the findings with community and Tribal Council members through regularly scheduled events and media is also an essential element of a successful community-engaged project.
Visioni marginali. Un?indagine comparativa sui processi di transizione ed innovazione sostenibili in due aree rurali periferiche
Creators: name: BIFFI, Oscar
Publisher: name: Universit� degli studi di Bergamo
Year: 2014

description: The aim of this research is to study attempts of transition to sustainability in marginal rural area of the Italian mountains, comparing two cases characterized by distinct historical, geographical and cultural contexts. Specifically, I have focused on sense of place and have argued for a diversity of "marginal visions", namely ways of seeing how to improve local socio-economic conditions. The San Martino and Stura valleys are compared and contrasted regarding their investments on local sustainable agriculture and ecomuseums. In both cases, local associations and institutions value heritage and landscape conservation. However, collaboration and communication between local networks and administrations is notable in one case and absent in another. Secondly, both the experiences - which to a point represent a bottom-up and a top-down sustainability initiative ? suffer from a lack of democratic decision-making in their internal governance.
Supplemental material4 - Supplemental material for The Noise Exposure Structured Interview (NESI): An Instrument for the Comprehensive Estimation of Lifetime Noise Exposure
Creators: name: Guest, Hannah
name: Dewey, Rebecca S.
name: Plack, Christopher J.
name: Couth, Samuel
name: Prendergast, Garreth
name: Bakay, Warren
name: Hall, Deborah A.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental material4 for The Noise Exposure Structured Interview (NESI): An Instrument for the Comprehensive Estimation of Lifetime Noise Exposure by Hannah Guest, Rebecca S. Dewey, Christopher J. Plack, Samuel Couth, Garreth Prendergast, Warren Bakay and Deborah A. Hall in Trends in Hearing
Supplemental material5 - Supplemental material for The Noise Exposure Structured Interview (NESI): An Instrument for the Comprehensive Estimation of Lifetime Noise Exposure
Creators: name: Guest, Hannah
name: Dewey, Rebecca S.
name: Plack, Christopher J.
name: Couth, Samuel
name: Prendergast, Garreth
name: Bakay, Warren
name: Hall, Deborah A.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental material5 for The Noise Exposure Structured Interview (NESI): An Instrument for the Comprehensive Estimation of Lifetime Noise Exposure by Hannah Guest, Rebecca S. Dewey, Christopher J. Plack, Samuel Couth, Garreth Prendergast, Warren Bakay and Deborah A. Hall in Trends in Hearing
Development of a novel RNA therapeutic to treat lung cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: KRAS is the most frequently mutated cancer-causing gene (oncogene) in human cancers. In lung cancer, the leading cause of cancer mortality worldwide, KRAS mutations are found in more than 30% of tumors. In healthy cells, KRAS acts as an "on-off" switch to control cell growth. Oncogenic KRAS mutations trap it in the "on" state, leading to uncontrolled cell growth, tumor development, and metastasis. While being an appealing target for decades, the development of drugs targeting such oncogenic KRAS mutants remains challenging. Hence, new therapies are urgently required.
 
 The flow of genetic information in biology follows a linear path, in which information content of DNA in cells is converted to an RNA message, which is then ‘read’ to make a protein. My research is focused on ADAR enzymes, that carry out targeted mutations (or edits) in the RNA message that is read by cells, thus changing the resultant protein. The Li lab has pioneered a gene therapy technique that harnesses ADAR’s RNA editing activity to fix disease-causing mutations in RNA. Using this approach, I will design small “guide RNA” drugs that can find and bind to mutant KRAS G12D RNA, and recruit ADAR enzymes to edit and correct the mutation. This technique overcomes challenges faced by other gene therapy platforms that require the delivery of bulky, foreign enzymes that lead to unwanted immune responses.
 
 I will vary the sequence of the guide RNA targeting KRAS G12D using an unbiased approach. This will enable the identification of the best guide RNA designs that lead to highest editing of the mutation, rapidly and at an unprecedented scale. The best designs will be used to repair the mutation in human lung cancer cells. Finally, the candidate drugs will be tested in mouse models of lung cancer, focusing on reduction of lung tumor growth. This study will establish the formulation of novel RNA drugs to treat KRAS-driven lung cancer and holds great potential to be a milestone in precision lung cancer therapy.
Supplemental_File_ORM-17-0075.R1-Final - Experience Sampling Methods: A Discussion of Critical Trends and Considerations for Scholarly Advancement
Creators: name: Gabriel, Allison S.
name: Podsakoff, Nathan P.
name: Beal, Daniel J.
name: Scott, Brent A.
name: Sonnentag, Sabine
name: Trougakos, John P.
name: Butts, Marcus M.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental_File_ORM-17-0075.R1-Final for Experience Sampling Methods: A Discussion of Critical Trends and Considerations for Scholarly Advancement by Allison S. Gabriel, Nathan P. Podsakoff, Daniel J. Beal, Brent A. Scott, Sabine Sonnentag, John P. Trougakos, and Marcus M. Butts in Organizational Research Methods
Search strings for systematic reviews: soil multifunctionality and land use drivers
Creators: name: Dingkuhn, Elsa L.
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Systematic Reviews as Topic/methods
subject: Methods
subject: Land use
subject: Soil function

description: This record entails the search strings that were used to conduct two distinct but related systematic literature reviews entitled:

Multifunctional land-use governance: Do we have the science to inform policy? A global systematic review

Land-use governance: The interplay of social, market, and policy drivers – A global systematic review

The record contains three files:

- README- Search strings_Systematic review_Soil functions- Search strings_Systematic review_Land use drivers
DS_10.11770_001839218804527 – Supplemental material for Subordinate Activation Tactics: Semi-professionals and Micro-level Institutional Change in Professional Organizations
Creators: name: Kellogg, Katherine C.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material, DS_10.11770_001839218804527 for Subordinate Activation Tactics: Semi-professionals and Micro-level Institutional Change in Professional Organizations by Katherine C. Kellogg in Administrative Science Quarterly
Therapeutic approach to prevent cancer cell adaptation to tobacco-induced stress and inflammation
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Short-term “acute” inflammation is essential for your body to heal itself after an injury or infection, but long-lasting “chronic” inflammation is too much of a good thing. Among the many dangers and complications of tobacco use is the promotion of a state of chronic inflammation that wreaks havoc in organs such as the lung and pancreas. When inflammation lingers for a long time, the immune system continues to pump out white blood cells that can end up attacking or damaging nearby healthy tissues and organs. Inflammation also leads to increased cell division, which provides an opportunity for cells to acquire mutations leading to cancer. 
 
 Although smoking is well known to create chronic inflammation and cancer in the lung, smoking also increases the incidence of pancreatitis, a chronic inflammatory state that can, in turn, increase the likelihood of developing pancreatic cancer. While smoking, cancer, and inflammation are clearly linked, a better understanding of what happens at the molecular level in the context of the unique environments of the pancreas will provide new opportunities to lock early-stage tumors in a drug sensitive state and to protect current and former smokers from developing pancreatic cancer. 
 
 The goal of our project is to examine how healthy cells from the pancreas change for the worse when they are subject to a chronic inflammatory state. We will focus on a particular pathway that we have previously linked to cancer initiation and progression, and ask how this pathway gets invoked during inflammation in the lung and pancreas. We propose that treating patients with drugs that will prevent cells from responding to chronic inflammation will not only provide a new opportunity to render tobacco-related cancers more sensitive to standard therapies, but may also prevent the transition of inflammation to cancer.
I mali del dis-abitare. Etnografia ed Etnopsichiatria a confronto tra sgomberi e sopravvivenza del popolo rom
Creators: name: PERRARO, Annachiara
Publisher: name: Universit� degli studi di Bergamo
Year: 2012

description: Home is the dwelling place of our cultural geographies. But what happens when we are forced to live in a place without being able to ?wear? the places of everyday life? Why is for someone marginal dwelling the only possible dwelling? Yet, in the history of human migrations, the different ways of dwelling and using space have always co-produced the plural city. Given the degraded condition in which they are often obliged to live, the dwelling issue is tightly linked to Romani and Sinti citizens. Space is a language. The spatial language imposed on this family (and on many others in Italy) only reveals ghettoizing housing policies, gates, fences, walls and barriers to protect from the gypsy enemies. The camps? country. The sick space which sickens the body. In this emptiness, in this kind of non-space, there nest sickness, uneasiness, the attempt to rescue one?s own belonging in a space which doesn?t recognize them and refuses them. Space closes around Roma and Sinti as a cage. The sickness that becomes a way to ?be free again?, to reconcile with memory, to feel ?Romani?. In Italy there are more and more often manifestations of psychic sickness among Romani and Sinti citizens obliged to live in camps. The sense of loss and segregation seems to constitute the unexpressed background of Romani and Sinti condition, both of those who get sick and of those who don?t. Some cases exist of apparent adaptation to the situation of living marginality into which they are forced, cases of attempts to deny their own belongings in order to assimilate to the gadje world. An illness that arises from the unheard desire to stitch up their origins, to find back a memory of the space that has been lost. Therefore illness becomes a kind of resistance to a space diaspora and a way to make unsaid emotions resurface through suffering and to tell stories of themselves... Diagnoses that western medicine defines as: severe migraines, depressive symptoms, hallucinations, anxiety states, panic attack. Diagnoses that often tell something else. Illness becomes the attempt to reconcile with the ancestors, with lands left far away and maybe forever lost, with the suffered marginality. Giving way to individual narratives means letting every person?s story?s uniqueness have voice and space. This is why I chose to present here the transcript of a case, one among many of those unheard stories.
Supplementary_Materials_(1) – Supplemental material for Adding insult to injury: Perceived inequity modulates pain perception
Creators: name: Hanqi Zhang
name: Haixia Wang
name: Jingyao Sun
name: Xiaofei Xie
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Supplementary_Materials_(1) for Adding insult to injury: Perceived inequity modulates pain perception by Hanqi Zhang, Haixia Wang, Jingyao Sun and Xiaofei Xie in Journal of Health Psychology
Dorytomus Germar 1817
Creators: name: Colonnelli, Enzo
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Dorytomus

description: Dorytomus Germar, 1817
[= D. subgen. Chaetodorytomus Iablokov­Khnzorian, 1970, syn. nov.; = D. subgen. Euolamus Reitter, 1916, syn. nov.; = D. subgen. Olamus Reitter, 1916, syn. nov.] (Colonnelli, hoc opus). As already rightly pointed out by Dieckmann (1986), followed by Korotyaev et al. (1993), Egorov, Zherikhin & Korotyaev (1996), Krivets & Korotyaev (1998), there is no possibility to give subgeneric rank to any of the names proposed by Reitter (1916) and by Iablokov­Khnzorian (1970), since rostral length, pubescence, kind of setae on anterolateral pronotal edge, and incisure of ventral fore margin of pronotum vary in almost continuous way. In addition, biology of the several species of Dorytomus does not support the division of its members in different subgenera.
description: Published as part of Colonnelli, Enzo, 2003, A revised checklist of Italian Curculionoidea (Coleoptera), pp. 1-142 in Zootaxa 337 (1) on page 9, DOI: 10.11646/zootaxa.337.1.1, http://zenodo.org/record/5019737
Targeting IL-33 for the treatment of SARS-CoV 2 respiratory disease in smokers
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The global COVID-19 pandemic continues to devastate. In California we are threatened with a new variant and a surge in cases in “hot spots’ that include Mendocino and Los Angeles counties. Furthermore, 38.5% of the CA population has not been fully vaccinated. The respiratory effects of a COVID-19 infection are horrible and, those who smoke cigarettes or have smoke related lung disease are more likely to suffer severe symptoms. Survival is low in these susceptible populations because cigarette smoking “primes” the lung by irritating and inflaming the bronchial passages. Upon infection with SARS-CoV-2, the lung immune system overreacts. This hyperactivity is termed a ‘cytokine storm’ and leads to failure of the lungs and many organs throughout the body. Currently, there are no treatments to successfully regain control of this deadly immune response. In this proposal we will test new designer drugs (IL-RAs) that we are engineering and producing in our laboratory. IL-RAs bind to receptors on several types of inflammatory cells in the lung, preventing this hyperinflammatory response. Significantly, we have found that one of the cytokines, IL-33, becomes more active after smoke exposure and is important in priming the lungs for this overreaction to viral infections. Thus, we will screen COVID patient serum samples for the presence of activated IL-1ß and IL-33 and correlate our findings to disease symptoms and smoking history. This will allow us to explore activated IL-1ß and IL-33 to be used as a biomarker for disease diagnosis. Newly designed IL-RAs will be tested in mice that have been exposed to cigarette smoke and challenged with SARS-CoV-2 components to determine how effective such antagonists are in dampening the hyperinflammatory response. Similar experiments will be performed in human lung cells and organ cultures infected with SARS-CoV-2 virus so that our results can be developed without delay for use in patients. Our hope is that the appropriate IL-RA can calm the “cytokine storm” triggered by SARS-CoV-2 infection but still allow the body’s own immune system to fight off the virus. These novel proteins may eventually be used in conjunction with drugs that directly target viruses, for example Remdesivir, or even with vaccines, as they sometimes give an unintended immune response.
RosatiSupplementalMaterial – Supplemental material for Chimpanzee Cooperation Is Fast and Independent From Self-Control
Creators: name: Rosati, Alexandra G.
name: DiNicola, Lauren M.
name: Buckholtz, Joshua W.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, RosatiSupplementalMaterial for Chimpanzee Cooperation Is Fast and Independent From Self-Control by Alexandra G. Rosati, Lauren DiNicola and Joshua W. Buckholtz in Psychological Science
Tobacco product regulation of breast cancer stemness and progression
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tobacco-use is linked to aggressive breast cancers that disproportionately affect African-American and Hispanic women. Despite this connection there are still no effective ways of identifying those patients likely to progress or treating this deadly disease. Thus, there is a great need for new methods of diagnosis and treatment strategies to combat aggressive tobacco-related breast cancers. We previously characterized a population of stem-like tumor cells similar to normal stem cells activated by hormones in the adult mammary gland, providing us with a unique perspective on breast cancer progression. Our preliminary findings now show that these stem-like cancer cells are found in nearly all tobacco-related estrogen receptor-negative (ER-) cancers that progress to form lethal metastatic disease. Interestingly, these cells were highly represented in the cancers of Hispanic women that smoked, suggesting a disproportionate effect on some racial and ethnic minorities. Thus, the goal of this study is to examine the hypothesis that tobacco products increase stemness, leading to more aggressive breast cancers. Our innovative approach will identify key genes expressed by stem-like cells exposed to nicotine and assess their function as biomarkers to predict progression. These studies will also be relevant to young women by providing a timely examination of a potential link between nicotine-use and an increased risk of developing breast cancer. Successful outcomes of these studies would represent an important breakthrough in the clinical care of tobacco-related breast cancers, allowing physicians to focus attention on patients at high risk of developing life-threating metastasis. To complement our biomarker studies we will also probe important signaling pathways in stem-like cells as possible drug targets. Taken together, our innovative approach may provide a much-needed means of identifying and treating aggressive tobacco-related breast cancers, particularly in vulnerable populations disproportionately burdened by commercial tobacco.
ASMOHEJP2021 poster 1 "In silico study of IS6110 sequences abundance and localisation evolution in three main Mycobacterium bovis French genotypes of endemic region"
Creators: name: CHARLES, Ciriac
name: MICHELET, Lorraine
name: BIET, Franck
name: Maria-Laura BOSCHIROLI
Publisher: name: Zenodo
Year: 2022

description: ASMOHEJP2021 poster 1
Eremiarhinus Fairmaire 1876
Creators: name: Colonnelli, Enzo
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Eremiarhinus

description: Eremiarhinus Fairmaire, 1876
is the oldest available name of Rhythirrinini to act as genus holding all other Palaearctic subgenera ­ in the meaning of Alonso­Zarazaga & Lyal (1999) ­ until a careful revision of the Palaearctic species will be published. In consequence, the following new combinations affecting the Italian species must be established: Eremiarhinus (Depresseremiarhinus) dilatatus (Fabricius, 1801), comb. nov.; Eremiarinus (Pseudorhinus) impressicollis (Boheman, 1834) jarrigei (Roudier, 1959); Eremiarhinus (Pseudorhinus) impressicollis luciae (Ragusa, 1883), comb. nov.; E. (Pseudorhinus) impressicollis peninsularis (F. Solari, 1940), comb. nov.; E. (Pseudorhinus) laesirostris (Fairmaire, 1859), comb. nov. (Meregalli, hoc opus).
description: Published as part of Colonnelli, Enzo, 2003, A revised checklist of Italian Curculionoidea (Coleoptera), pp. 1-142 in Zootaxa 337 (1) on page 10, DOI: 10.11646/zootaxa.337.1.1, http://zenodo.org/record/5019737
GhaffariOpenPracticesDisclosure – Supplemental material for The Power of Attention: Using Eye Gaze to Predict Other-Regarding and Moral Choices
Creators: name: Minou Ghaffari
name: Fiedler, Susann
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, GhaffariOpenPracticesDisclosure for The Power of Attention: Using Eye Gaze to Predict Other-Regarding and Moral Choices by Minou Ghaffari and Susann Fiedler in Psychological Science
GharfarriSupplementalMaterial – Supplemental material for The Power of Attention: Using Eye Gaze to Predict Other-Regarding and Moral Choices
Creators: name: Minou Ghaffari
name: Fiedler, Susann
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, GharfarriSupplementalMaterial for The Power of Attention: Using Eye Gaze to Predict Other-Regarding and Moral Choices by Minou Ghaffari and Susann Fiedler in Psychological Science
GenoMed4All: Artificial Intelligence-based Deep Learning algorithms for patients with Sickle Cell Disease
Creators: name: Idrizovic, Amira
name: van der Veen, Sigrid
name: Mañú, María del Mar
name: Collado, Anna
name: Colombatti, Rafaella
name: Boaro, Maria Paola
name: Bartolucci, Pablo
name: de Montalembert, Mariane
name: Cnossen, Marjon H.
name: Biemond, Bart J.
name: Kleanthous, Marina
name: van Beers, Eduard J.
name: Kountouris, Petros
Publisher: name: Zenodo
Year: 2022
Subjects: Sickle Cell Disease, Artificial Intelligence, Deep Learning, Oxygenscan

description: Poster presentation at IUBMB Focused Meeting – Hemoglobin Switching Conference (5th-9th May 2022) at Crete, Greece
Kultura bezpieczeństwa. Przegląd problematyki.pdf
Creators: name: Kochańska, Małgorzata
name: Kowalski, Cezary
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology

description: W artykule przedstawiono podstawowe zagadnienia związane z kulturą bezpieczeństwa. Bezpieczeństwo jako stan dający poczucie pewności i gwarancję jego zachowania oraz szansę na doskonalenie[1] wraz z jego wytworzonym psychicznym (duchowy) i materialnym dorobkiem społeczeństwa, organizacji, tworzy swoisty konglomerat psychologicznych, społecznych i organizacyjnych czynników uruchamiających lub podtrzymujących działania chroniące życie i zdrowie człowieka. Człowieka nie tylko w procesie pracy ale także poza nim
 [1] Słownik terminów z zakresu bezpieczeństwa narodowego. Akademia Obrony Narodowej, Warszawa 2008. s. 14
Silicone wristbands to measure secondhand exposure to tobacco, electronic cigarettes and cannabis
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Achieving the goals of the Tobacco Endgame requires simple methods to widely assess and track reductions in tobacco-related product use and exposure, especially in vulnerable populations. Children and youth are particularly susceptible to the harmful effects of secondhand and thirdhand tobacco smoke. In addition, concerns are rising about increasing secondhand exposure to electronic cigarette/ cannabis exhaled vapor and cannabis smoke. To determine if tobacco control efforts and policies are making progress in protecting children, or to study health effects, measuring how much exposure children have is important. However, measuring exposure to tobacco smoke chemicals in children is difficult and can be invasive, for example if we ask for a urine or saliva sample. Simple measurement methods that have high acceptability and are easy to deploy without training or invasive sampling are needed. This study will evaluate whether a community-friendly simple silicone wristband can be worn and used as a sampler to absorb and record children and youth exposure to nicotine and other toxic compounds in tobacco smoke, electronic cigarettes and cannabis. In a pilot TRDRP-funded study, we showed that the wristbands worn by children can detect nicotine in tobacco smoke and electronic cigarettes and that this amount is related to absorbed nicotine dose in a predictable manner. However, further investigations are needed to fully realize the potential of the simple silicone wristband samplers for community tobacco control. Here we will follow up on our successful pilot study and measure multiple compounds related to tobacco smoke, electronic cigarette vapor, and cannabis vapor or smoke in wristbands worn by children and youth exposed secondhand to these products. We will rigorously test translational aspects of the wristband samplers, such as stability and accuracy of compounds detected when the wristband samplers are mailed. To achieve these aims, we will recruit children exposed to a variety of tobacco-related and cannabis products through their caregivers, as well as conduct laboratory and field testing of the samplers. The silicone wristband is simple to give to interested people, easy to wear, and can also be sent by mail or handed out at community events to increase inclusion of diverse communities in tobacco-prevention programs and can further the Tobacco Endgame.
Exapion Bedel 1887
Creators: name: Colonnelli, Enzo
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Brentidae
Exapion

description: Exapion Bedel, 1887
[= E. subgen. Ulapion Ehret, 1997, syn. nov.] (Colonnelli, hoc opus). It is impossible to give subgeneric rank to the members of the ulicis group until a careful revision of all Exapion has been done.
description: Published as part of Colonnelli, Enzo, 2003, A revised checklist of Italian Curculionoidea (Coleoptera), pp. 1-142 in Zootaxa 337 (1) on page 10, DOI: 10.11646/zootaxa.337.1.1, http://zenodo.org/record/5019737
Supplemental Material, PFR_711018-Supplements - Fiscal Governance, Information Capacity, and Subnational Capital Finance
Creators: name: Tima T. Moldogaziev
name: Espinosa, Salvador
name: Martell, Christine R.
Publisher: name: SAGE Journals
Year: 2017
Subjects: subject: Economics
subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental Material, PFR_711018-Supplements for Fiscal Governance, Information Capacity, and Subnational Capital Finance by Tima T. Moldogaziev, Salvador Espinosa, and Christine R. Martell in Public Finance Review
Thirdhand Smoke Research Consortium: THS Messaging Among Priority Populations
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Thirdhand smoke (THS) is the toxic residue left behind in spaces where tobacco products were previously used. While people can recognize the unpleasant odor and unsightly stains from THS, few are aware that THS exposure is bad for human health and can be an expensive problem. Understanding how people experience and perceive the risks of THS is central to the Tobacco Endgame, which seeks to ensure that everyone is protected from tobacco-related health risks. This is particularly true for minority, low-income, and underserved communities who are the most likely to be exposed to THS. To effectively counter tobacco industry efforts in communities that have received the most tobacco marketing, the purpose of this project is to develop and test messages to educate priority populations about THS and build support for THS prevention and Tobacco Endgame policies. This goal will be accomplished in three steps and will focus on the priority populations of low-income adults from Hispanic/Latino, Black/African, Asian/Pacific Islander, and LGBTQ+ communities. First, the identified priority populations will be asked to share their experiences with, and perceptions of, THS. This will be done through focus groups with California members of the priority populations and through a national survey of members of the priority populations. Second, the findings from the first step will be used to develop messages. Following the guidance of a theoretical framework that emphasizes cultural aspects of populations, messages will be designed to leverage unique THS experiences within each priority population. The developed messages will be pre-tested in a national online survey with members of the priority populations. Finally, in step three, messages that were found to be persuasive in phase two will be used in a social media-based campaign targeting California priority populations. User engagement data will be collected and analyzed to determine which messages were the most effective at reaching and persuading priority populations. Through population targeted messaging, THS awareness and knowledge is expected to increase, resulting in greater intentions to prevent THS exposure. Findings from this project will provide suggestions for tobacco control efforts, including Tobacco Endgame policy plans, for reaching and persuading members of these priority populations.
Thirdhand Smoke Disparities, Harm and Risk in Children
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: In this Subsidiary Award in the Thirdhand Smoke Consortium, we study whether smoking in indoor environments results in house dust contaminated with toxic metals such as lead, cadmium, and arsenic. The toxic residue of smoking indoors, called thirdhand smoke (THS), has been shown to contain numerous toxic compounds, but metals have not been studied hardly at all. We will also examine markers of exposure and harn in urine from children living in the homes. Our study will use samples already collected as part of clinical study directed by Dr. Mahabee-Gittens, a pediatrician at Cincinnati Children’s Medical Center (NIH R01ES030743). Because clinical studies in children are very expensive, using already collected samples is a very cost-effective way to investigate our question about harms from metals in house dust. We have previously found that lead and cadmium in dust samples from low income homes were related to nicotine in the same sample, which suggests that tobacco smoking can be a source of these toxic metals. We are also investigating disparities in exposures to and risks of thirdhand smoke related to income, housing type and race/ethnicity. We will bring together data on house dust from our previous funded projects and obtain new data on these archived samples to get data on the same set of toxic chemicals. We will measure novel toxic compounds we have previously identified in house dust contaminated with THS through non-targeted chemical analysis, which is a method of finding unknown chemicals in environmental samples. We want to find out if a disproportionate burden of involuntary THS exposure and risk is borne by low-income and minority communities. This may help to leverage resources for prevention.We will also continue to develop direct-reading and simple tests for finding out thirdhand smoke contamination of homes. Our proposal will also collaborate with the Lead Award of the Thirdhand Smoke Consortium to come up with suggested Voluntary Reference Levels, (meaning the amount of nicotine or other chemicals inside your homes would be expected when no-one has smoked inside). This could help renters and homebuyers decide if the home is contaminated or not with THS. Our THS research will inform and contribute to the California Tobacco Endgame Initiative which seeks to end the sale and use of all tobacco products in the state by the year 2035.
Supplemental Material, Figure7a - The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions
Creators: name: Schouten, Rianne Margaretha
name: Vink, Gerko
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Sociology

description: Supplemental Material, Figure7a for The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions by Rianne Margaretha Schouten, and Gerko Vink in Sociological Methods & Research
Larinus ursus N C S Si Sa
Creators: name: Colonnelli, Enzo
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Larinus
Larinus ursus

description: Larinus ursus (Fabricius, 1792)
[= L. carinirostris Gyllenhal, 1837, syn. nov.; = L. genei Boheman, 1843, syn. nov.] (Colonnelli, hoc opus). The lack of any reliable biological differential trait and the variability of this species, even within the same population, are so wide to make it impossible to give subspecific rank to any of the synonymized names.
description: Published as part of Colonnelli, Enzo, 2003, A revised checklist of Italian Curculionoidea (Coleoptera), pp. 1-142 in Zootaxa 337 (1) on page 10, DOI: 10.11646/zootaxa.337.1.1, http://zenodo.org/record/5019737
Supplemental Material, Figure8f - The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions
Creators: name: Schouten, Rianne Margaretha
name: Vink, Gerko
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Sociology

description: Supplemental Material, Figure8f for The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions by Rianne Margaretha Schouten, and Gerko Vink in Sociological Methods & Research
Supplemental Material, Figure9a - The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions
Creators: name: Schouten, Rianne Margaretha
name: Vink, Gerko
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Sociology

description: Supplemental Material, Figure9a for The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions by Rianne Margaretha Schouten, and Gerko Vink in Sociological Methods & Research
Supplemental Material, Figure9c - The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions
Creators: name: Schouten, Rianne Margaretha
name: Vink, Gerko
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Sociology

description: Supplemental Material, Figure9c for The Dance of the Mechanisms: How Observed Information Influences the Validity of Missingness Assumptions by Rianne Margaretha Schouten, and Gerko Vink in Sociological Methods & Research
Metacinops rhinomacer Kraatz 1862
Creators: name: Colonnelli, Enzo
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Metacinops
Metacinops rhinomacer

description: Metacinops rhinomacer Kraatz, 1862
[= M. calabrus Stierlin, 1892, syn. nov.] (Colonnelli, hoc opus). Due to the wide range of variation of this species, it is impossible to find a single feature separating the Greek examples from the specimens collected in the south of Italian peninsula. Recollection of long series of M. siculus Osella & Di Marco, 1996 may also most probably prove that this is another synonym of M. rhinomacer.
description: Published as part of Colonnelli, Enzo, 2003, A revised checklist of Italian Curculionoidea (Coleoptera), pp. 1-142 in Zootaxa 337 (1) on page 10, DOI: 10.11646/zootaxa.337.1.1, http://zenodo.org/record/5019737