cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
North Carolina in the New Economy: Case Studies from the North Carolina Chapter of the American Planning Association
Creators: name: Hight, Lance
name: Mizelle, Jenny
name: Morck, John
name: Lentz, Rodger
name: Hitchings, Ben
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Carolina Planning regularly publishes a feature highlighting projects from members of the North Carolina Chapter of the American Planning Association (APA-NC). These stories feature economies transitioning from manufacturing to services and culture and generational shifts in values and community preferences. Includes articles: The Economic Value of Planning; Planning for Prosperity: Understanding the Economic Perceptions and Community Preferences of the Millennial Generation; Planning for Arts and Innovation in Wilson, NC; Honoring Tradition, Supporting Innovation: Redevelopment of Conover Station; Long-Term Economic Development Strategies for a Growing Triangle Town
Structure formation of surfactant membranes under shear flow
Creators: name: Shiba, Hayato
name: Noguchi, Hiroshi
name: Gompper, Gerhard
Publisher: name: arXiv
Year: 2013
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Shear-flow-induced structure formation in surfactant-water mixtures is investigated numerically using a meshless-membrane model in combination with a particle-based hydrodynamics simulation approach for the solvent. At low shear rates, uni-lamellar vesicles and planar lamellae structures are formed at small and large membrane volume fractions, respectively. At high shear rates, lamellar states exhibit an undulation instability, leading to rolled or cylindrical membrane shapes oriented in the flow direction. The spatial symmetry and structure factor of this rolled state agree with those of intermediate states during lamellar-to-onion transition measured by time-resolved scatting experiments. Structural evolution in time exhibits a moderate dependence on the initial condition.
description: 12 pages, 13 figures
title: AutorInnen dieses Heftes
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2016

description: kritische berichte - Zeitschrift für Kunst- und Kulturwissenschaften, Bd. 38, Nr. 2 (2010): kritische berichte, Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
The double RGB in M 2: C, N, Sr and Ba abundances
Creators: name: Lardo, C.
name: Pancino, E.
name: Mucciarelli, A.
name: Bellazzini, M.
name: Rejkuba, M.
name: Marinoni, S.
name: Cocozza, G.
name: Altavilla, G.
name: Ragaini, S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The globular cluster M 2 has a photometrically detected double red giant branch (RGB) sequence. We investigate here the chemical differences between the two RGBs in order to gain insight in the star formation history of this cluster. The low-resolution spectra, covering the blue spectral range, were collected with the MODS spectrograph on the LBT, and analyzed via spectrum synthesis technique. The high quality of the spectra allows us to measure C, N, Ba, and Sr abundances relative to iron for 15 RGB stars distributed along the two sequences. We add to the MODS sample C and N measurements for 35 additional stars belonging to the blue RGB sequence, presented in Lardo et al. (2012). We find a clear separation between the two groups of stars in s-process elements as well as C and N content. Both groups display a C-N anti-correlation and the red RGB stars are on average richer in C and N with respect to the blue RGB. Our results reinforce the suggestion that M2 belongs to the family of globular clusters with complex star formation history, together with Omega Cen, NGC 1851, and M 22.
description: 11 pages, 8 figures. Accepted for publication in MNRAS
Bay Area Blueprint: Worker Cooperatives as a Community Economic Development Strategy
Creators: name: Lingane, Alison
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The growing low-wage service sector in our economy, combined with overall wage and wealth gaps that are especially concentrated in communities of color, means many working adults don’t make enough money to cover basic needs. Businesses that are owned and run by their workers offer a different way of doing business that benefits workers, businesses, and society. Worker coops are a key component of a “new economy,” and as such, Community Economic Development efforts should incorporate worker cooperative development into their strategies. This paper describes a project in the Bay Area of California to create a local action plan for moving towards scale and impact of worker cooperative development by engaging multi-sectoral actors. It includes a framework for assessing the opportunities in a local region to increase worker coops to benefit low wage workers, and takeaways for other regions that want to apply a similar approach.
Identifizierung und Charakterisierung neuartiger α-Amylasen aus Basidiomycota für die Waschmittelindustrie
Creators: name: Döring, Florian
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2018
Subjects: subject: secretome
subject: detergent
subject: Screening
subject: Sekretom
subject: Basidiomycota
subject: α-Amylase
subject: Waschmittel
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: Der Einsatz von Enzymen in Waschmittelformulierungen steigt seit Jahrzehnten beständig an. Zu den am meist verwendeten Enzymen gehören die α-Amylasen, wobei deren bakterieller Ursprung überwiegt. Zudem sind Pilze in der Lage eine Vielfalt an extrazellulären Enzymen zu bilden, um sich ihren Lebensraum zu erschließen. In der vorliegenden Arbeit wurden neuartige pilzliche α-Amylasen für den Einsatz in Waschmittelformulierungen gesucht. Insgesamt wurden dabei über 50 verschiedene Basidiomycota kultiviert und deren Sekretom nach waschaktiven α-Amylasen gescreent. Dafür wurden sowohl Aktivitätsassays als auch Applikationsstudien durchgeführt. Es stellte sich heraus, dass mit Rhizoctonia solani, Trametes hirsuta, Irpex lacteus, Fomes fomentarius, Fomitopsis pinicola, Pleurotus sajor-caju, Pycnoporus sanguineus und Lentinus strygosus acht Stämme α-Amylasen mit einer verbesserten Waschleistung produzierten. Es gelang dabei nach einer Reinigung mittels IEX und anschließender Analyse mittels SDS-PAGE sowie Zymografien, die waschaktiven Enzyme zu separieren und mittels Massenspektrometrie zu identifizieren. Anhand der durchgeführten de-novo Sequenzierung konnten die α-Amylasen von R. solani, T. hirsuta, I. lacteus, F. fomentarius, F. pinicola, und P. sanguineus identifiziert werden. Ausgehend von den korrespondierenden Genomdaten wurden Primer abgeleitet und schließlich die codierenden Gene amplifiziert. Bei einem Vergleich der α-Amylasen zeigte sich, dass Amylasen mit einer Stärke bindenden Domäne, der CBM20, die besten Waschleistungen im isoaktiven Vergleich erzielten. Von sechs identifizierten α-Amylasen weisen R. solani, T. hirsuta, F. fomentarius und F. pinicola diese Domäne auf, was verglichen mit der natürlichen Auftrittswahrscheinlichkeit von zehn Prozent eine Anhäufung zeigt. Der Versuch einige ausgewählte α-Amylase-Gene in Komagataella phaffii zu exprimieren, führte nicht zum gewünschten Erfolg, auch nicht mit Hilfe von molekularbiologischen Varianten, wie der Anpassung der codon usage, der Änderung der Signalsequenzen oder der Produktion als Fusionsprotein. Daher sollte mit Aspergillus oryzae ein neuer Expressionsstamm designt werden, bei welchem mittels der CRISPR-Technik die wirtseigenen Amylasen ausgeknockt werden sollten. Nach der Sequenzierung der Genombereiche, stellte sich heraus, dass es zu keinen CRISPR vermittelten Deletionen im Bereich der Zielgene gekommen war.
title: Wieviel science, wieviel fiction?
Creators: name: Leonhard, Karin
Publisher: name: University Library Heidelberg
Year: 2016

description: kritische berichte - Zeitschrift für Kunst- und Kulturwissenschaften, Bd. 38, Nr. 3 (2010): kritische berichte, Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Gilkey-de Witt heat kernel expansion and zero modes
Creators: name: Alonso-Izquierdo, Alberto
name: Mateos-Guilarte, Juan
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we propose a generalization of the Gilkey-de Witt heat kernel expansion, designed to provide us with a precise estimation of the heat trace of non-negative Schroedinger type differential operators with non-trivial kernel over all the domain of its "inverse temperature" variable. We apply this modified approach to compute effectively the one-loop kink mass shift for some models whose kink fluctuation operator spectrum is unknown and the only alternative to estimate this magnitude is the use of the heat kernel expansion techniques.
description: 11 pages, 3 figures, for the proceedings of the conference Mathematical Structures in Quantum Systems, Benasque, Spain, July 2012, to be published in Nuovo Cimento
title: Vasenekstase: Exorzismus deutscher Befindlichkeiten in den Fotografien von Anna und Bernhard Johannes Blume
Creators: name: Schröder, Gerald
Publisher: name: University Library Heidelberg
Year: 2016

description: kritische berichte - Zeitschrift für Kunst- und Kulturwissenschaften, Bd. 38, Nr. 4 (2010): kritische berichte, Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Cover Photo Runner Ups: The Phoenix and the Renaissance of a Historic Community: New Bern
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: This century old building on Queen St, the historical divide between predominantly white, downtown New Bern and the largely African American communities of Dryborough and Duffyfield (amongst others). This building stands as a reminder of this community’s proud past, its troubled present and its bright future. A thriving community on the edge of New Bern throughout much of the 19th Century, a great fire decimated many of the homes and businesses throughout Dryborough and the greater Duffyfield neighborhoods in 1922, leaving thousands homeless. The mural seen on the side of this building, created by Dominican Republic artists in a joint venture with Craven Community College and the City of New Bern in 2012, depicts the Great Fire and the Phoenix rising from its ashes. Just as the Phoenix rose, so to did this community.
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
Creators: name: The Cancer Genome Atlas Research Network
name: Perou, Charles
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: BACKGROUND
Diffuse low-grade and intermediate-grade gliomas (which together make up the lower-grade gliomas, World Health Organization grades II and III) have highly variable clinical behavior that is not adequately predicted on the basis of histologic class. Some are indolent; others quickly progress to glioblastoma. The uncertainty is compounded by interobserver variability in histologic diagnosis. Mutations in IDH, TP53, and ATRX and codeletion of chromosome arms 1p and 19q (1p/19q codeletion) have been implicated as clinically relevant markers of lower-grade gliomas.
METHODS
We performed genomewide analyses of 293 lower-grade gliomas from adults, incorporating exome sequence, DNA copy number, DNA methylation, messenger RNA expression, microRNA expression, and targeted protein expression. These data were integrated and tested for correlation with clinical outcomes.
RESULTS
Unsupervised clustering of mutations and data from RNA, DNA-copy-number, and DNA-methylation platforms uncovered concordant classification of three robust, nonoverlapping, prognostically significant subtypes of lower-grade glioma that were captured more accurately by IDH, 1p/19q, and TP53 status than by histologic class. Patients who had lower-grade gliomas with an IDH mutation and 1p/19q codeletion had the most favorable clinical outcomes. Their gliomas harbored mutations in CIC, FUBP1, NOTCH1, and the TERT promoter. Nearly all lower-grade gliomas with IDH mutations and no 1p/19q codeletion had mutations in TP53 (94%) and ATRX inactivation (86%). The large majority of lower-grade gliomas without an IDH mutation had genomic aberrations and clinical behavior strikingly similar to those found in primary glioblastoma.
CONCLUSIONS
The integration of genomewide data from multiple platforms delineated three molecular classes of lower-grade gliomas that were more concordant with IDH, 1p/19q, and TP53 status than with histologic class. Lower-grade gliomas with an IDH mutation either had 1p/19q codeletion or carried a TP53 mutation. Most lower-grade gliomas without an IDH mutation were molecularly and clinically similar to glioblastoma. (Funded by the National Institutes of Health.)
Diffraction of surface wave on conducting rectangular wedge
Creators: name: Kotelnikov, Igor A.
name: Gerasimov, Vasily V.
name: Knyazev, Boris A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Diffraction of a surface wave on a rectangular wedge with impedance faces is studied using the Sommerfeld-Malyuzhinets technique. An analog of Landau's bypass rule in the theory of plasma waves is introduced for selection of a correct branch of the Sommerfeld integral, and the exact solution is given in terms of imaginary error function. The formula derived is valid both in the near-field and far-wave zones. It is shown that a diffracted surface wave is completely scattered into freely propagating electromagnetic waves and neither reflected nor transmitted surface waves are generated in case of bare metals which have positive real part of surface impedance. The scattered waves propagate predominantly at a grazing angle along the direction of propagation of the incident surface wave and mainly in the upper hemisphere regarding the wedge face. The profile of radiated intensity is nonmonotonic and does not resemble the surface wave profile which exponentially evanesces with the distance from the wedge face. Comparison with experiments carried out in the terahertz spectral range at Novosibirsk free electron laser has shown a good agreement of the theory and the experiments.
description: 26 pages, 11 figures, 33 references
Alternative scales for measuring service quality: A comparative assessment based on psychometric and diagnostic criteria
Creators: name: Berry, Leonard L.
name: Parasuraman, A.
name: Zeithaml, Valarie A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Service quality measurement is an area of growing interest to researchers and managers. It is also an area characterized by debate concerning the need for measuring customer expectations and how they should be measured. Building on a synthesis of the extant literature on customer expectations and service quality measurement, this article identifies unresolved issues and develops three alternative questionnaire formats to address them. It then discusses an empirical study that evaluated the three formats in four different sectors. The article concludes with practical implications and directions for further research stemming from the study's findings.
Einstein@Home search for periodic gravitational waves in LIGO S4 data
Creators: name: Abbott, B.P.
name: Abbott, R.
name: Adhikari, R.
name: Ajith, P.
name: Allen, Bruce
name: Aufmuth, Peter
name: Aulbert, C.
name: Brinkmann, M.
name: Burmeister, O.
name: Danzmann, Karsten
name: Fehrmann, H.
name: Gossler, S.
name: Grote, Hartmut
name: Hage, B.
name: Hewitson, M.
name: Kwee, P.
name: Lück, Harald
name: Machenschalk, Bernd
name: Meier, T.
name: Messenger, C.J.
name: Mossavi, K.
name: Müller-Ebhardt, H.
name: Pletsch, H.J.
name: Prix, R.
name: Rainer, N.
name: Rehbein, H.
name: Rüdiger, A.
name: Schilling, R.
name: Schnabel, Roman
name: Seifert, F.
name: Somiya, K.
name: Thüring, A.
name: Weinert, M.
name: Willke, B.
name: Et Al.
Publisher: name: College Park, MD : American Physical Society
Year: 2009
Subjects: subject: Gravitational waves
subject: Laser Interferometer Gravitational-wave Observatory
subject: GW detection
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: A search for periodic gravitational waves, from sources such as isolated rapidly spinning neutron stars, was carried out using 510 h of data from the fourth LIGO science run (S4). The search was for quasimonochromatic waves in the frequency range from 50 to 1500 Hz, with a linear frequency drift ˙f (measured at the solar system barycenter) in the range −f/τ<˙f<0.1f/τ, where the minimum spin-down age τ was 1000 yr for signals below 300 Hz and 10 000 yr above 300 Hz. The main computational work of the search was distributed over approximately 100 000 computers volunteered by the general public. This large computing power allowed the use of a relatively long coherent integration time of 30 h, despite the large parameter space searched. No statistically significant signals were found. The sensitivity of the search is estimated, along with the fraction of parameter space that was vetoed because of contamination by instrumental artifacts. In the 100 to 200 Hz band, more than 90% of sources with dimensionless gravitational-wave strain amplitude greater than 10−23 would have been detected.
Characterising the Anisotropic Mechanical Properties of Excised Human Skin
Creators: name: Annaidh, Aisling Ni
name: Bruyere, Karine
name: Destrade, Michel
name: Gilchrist, Michael D.
name: Ottenio, Melanie
Publisher: name: arXiv
Year: 2013
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: Medical Physics (physics.med-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: The mechanical properties of skin are important for a number of applications including surgery, dermatology, impact biomechanics and forensic science. In this study we have investigated the influence of location and orientation on the deformation characteristics of 56 samples of excised human skin. Uniaxial tensile tests were carried out at a strain rate of 0.012s$^{-1}$ on skin from the back. Digital Image Correlation was used for 2D strain measurement and a histological examination of the dermis was also performed. The mean ultimate tensile strength (UTS) was 21.6$\pm$8.4MPa, the mean failure strain 54$\pm$17%, the mean initial slope 1.18$\pm$0.88MPa, the mean elastic modulus 83.3$\pm$34.9MPa and the mean strain energy was 3.6$\pm$1.6MJ/m$^3$. A multivariate analysis of variance has shown that these mechanical properties of skin are dependent upon the orientation of Langer lines (P$
description: 23 pages
Pastor W.B.L gefunden : Henrich Pape als Verfasser der Artikelserie zur Verbesserung der Liturgie identifiziert
Creators: name: Lütjen, Andreas
Publisher: name: Soltau : Mundschenk
Year: 2021
Subjects: subject: Pape, Henrich
subject: Wulsbüttel
subject: Visselhövede
subject: Niederdeutsch
subject: Zweisprachigkeit
subject: Dewey Decimal Classification::200 | Religion, Religionsphilosophie
subject: Dewey Decimal Classification::400 | Sprache, Linguistik
subject: Dewey Decimal Classification::900 | Geschichte und Geografie

description: Henrich Pape wurde am 9. März 1745 in Bremen geboren und starb am 18. April 1805 in Visselhövede. Nach dem Besuch von Domschule und Athenaeum in Bremen studierte er ab 1766 Theologie an der Universität Göttingen. Im Jahr 1770 wurde Pape nach Abschluss seines Studiums zunächst Kandidat in Stade und trat noch im selben Jahr seine erste Predigerstelle in Wulsbüttel im Herzogtum Bremen an. In dieser Phase seines Lebens ist auch die Artikelserie „Von der Verbesserung der Liturgie und des Kirchenrituals“ entstanden, da er erst 1783 als Pfarrer nach Visselhövede im Herzogtum Verden berufen wurde.
title: Dendrochronologie. Vom Jahrring über den Kalender zu Baudatum und Dorfplan
Creators: name: Nelle, Oliver
Publisher: name: University Library Heidelberg
Year: 2016

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 45, Nr. 1 (2016), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
title: Nachruf Wolf Deiseroth
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2016

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 45, Nr. 1 (2016), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
Inferring effective field observables from a discrete model
Creators: name: Bény, Cédric
Publisher: name: Bristol : Institute of Physics Publishing
Year: 2017
Subjects: subject: central limit theorem
subject: Fisher information metric
subject: quantum field theory
subject: quantum information
subject: Fisher information matrix
subject: Lattice theory
subject: Quantum optics
subject: Quantum theory
subject: Asymptotic behaviour
subject: Central Limit Theorem
subject: Discrete modeling
subject: Distinguishability
subject: Quantum field theory
subject: Quantum Information
subject: Resolution parameters
subject: Computation theory
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: A spin system on a lattice can usually be modeled at large scales by an effective quantum field theory. A key mathematical result relating the two descriptions is the quantum central limit theorem, which shows that certain spin observables satisfy an algebra of bosonic fields under certain conditions. Here, we show that these particular observables and conditions are the relevant ones for an observer with certain limited abilities to resolve spatial locations as well as spin values. This is shown by computing the asymptotic behaviour of a quantum Fisher information metric as function of the resolution parameters. The relevant observables characterise the state perturbations whose distinguishability does not decay too fast as a function of spatial or spin resolution.
Tate Cycles on Abelian Varieties with Complex Multiplication
Creators: name: Murty, V. Kumar
name: Patankar, Vijay M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We consider Tate cycles on an Abelian variety $A$ defined over a sufficiently large number field $K$ and having complex multiplication. We show that there is an effective bound $C = C(A,K)$ so that to check whether a given cohomology class is a Tate class on $A$, it suffices to check the action of Frobenius elements at primes $v$ of norm $ \leq C$. We also show that for a set of primes $v$ of $K$ of density 1, the space of Tate cycles on the special fibre $A_v$ of the Néron model of $A$ is isomorphic to the space of Tate cycles on $A$ itself.
Paramagnetic NMR chemical shift in a spin state subject to zero-field splitting
Creators: name: Soncini, Alessandro
name: Heuvel, Willem Van den
Publisher: name: arXiv
Year: 2012
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: FOS: Physical sciences

description: We derive a general formula for the paramagnetic NMR nuclear shielding tensor of an open-shell molecule in a pure spin state, subject to a zero-field splitting (ZFS). Our findings are in contradiction with a previous proposal. We present a simple application of the newly derived formula to the case of a triplet ground state split by an easy-plane ZFS spin Hamiltonian. When $kT$ is much smaller than the ZFS gap, thus a single non-degenerate level is thermally populated, our approach correctly predicts a temperature-independent paramagnetic shift, while the previous theory leads to a Curie temperature dependence.
Untersuchungen zur Synthese eines strukturell vereinfachten Pradimicin-Gerüsts : CO-freie Carbonylierungsreaktionen, Modellversuche zur stereoselektiven Biaryl-Kupplung und Synthese eines neuen 9,10-Phenanthrenchinons
Creators: name: Weber, Regina
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2018
Subjects: subject: Carbonylierung
subject: N-Formylsaccharin
subject: atropdiastereoselektive Biaryl-Kupplung
subject: Molybdän(V)chlorid
subject: 9,10-Phenanthrenchinone
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: Das Carbohydrate Binding Agent Pradimicin gilt auf Grund seiner spezifischen Interaktion mit Mannose und Calcium-Ionen als Wirkstoff gegen das HI-Virus. Diese spezifische Interaktion beschränkt sich dabei auf das 9,10 Phenanthrengerüst als Teilstruktur des Pradimicins. Trotz bekannter Totalsynthesen des vollständigen Benzo[a]naphthacenchinongerüsts von Pradimicin liegen bisher keine Untersuchungen zur Synthese vereinfachter Pradimicinderivate und ihrer anti-viralen Eigenschaften vor. Ziel dieser Arbeit war es, ein vereinfachtes Pradimicin-Derivat mit einem Phenanthrengerüst herzustellen, welches die Ringe A, B und C des Naturstoffs enthält. Der Vorläufer des A-Rings konnte aus dem Orsellinsäureethylester in Carbonylierungs-reaktionen mittels des Carbonylierungsreagenz N-Formylsaccharin, sowie nach einer Suzuki-Reaktion mit einer Styrolboronsäure und anschließender Spaltung der Doppelbindung synthetisiert werden. Damit liegt eine Ausgangsverbindung für die Bildung des Rings B durch eine Biaryl-Kupplung der Ringe A und C vor. Für Modellversuche der atropdiastereoselektiven Biaryl-Kupplung wurde der Vorläufer des C-Rings mit Auxiliaren auf Basis von Glucose und Weinsäure verestert. Da die angewandten Reaktionsbedingungen nicht erfolgreich waren, wurde ein alternativer Syntheseweg über ein 9,10-Phenanthrenchinon als Schlüsselintermediat eingeschlagen. Die Bildung des dadurch unerwartet entstandenen Regioisomers kann mechanistisch erklärt werden.
The Watershed Performance Zone: A Strategy for Protecting High Point's Water Supply
Creators: name: Pugh, Mary Joan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Realizing that a good water supply is an essential ingredient in economic development and that future water resources such as Randleman Lake are both uncertain and expensive, the City of High Point decided to evaluate its present water supply resources. The objectives of the study were to assess the quality and quantity of present water supplies, to identify potential problems, and to recommend strategies to address the problems so that the City will continue to have an adequate supply of good quality water to meet future needs. For High Point, located in the headwaters of the Cape Fear River Basin, the main concern is the quality and quantity of the stormwater runoff from the watershed rather than the wastewater discharges from points upstream. Unlike most cities. High Point does not receive water from rivers originating outside of the area. Instead it depends entirely on stormwater runoff that results when rain falls in the watershed, accumulates and flows over the land via drainageways and small streams into water supply lakes.
Untersuchungen zum Phytoestrogen 8-Prenylnaringenin aus Hopfen für den Einsatz in der Hormon-Ersatz-Therapie
Creators: name: Schaefer, Olaf
Publisher: name: Hannover : Universität
Year: 2004
Subjects: subject: Hormontherapie
subject: Menopause
subject: Osteoporose
subject: Prenylnaringenin
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit

description: [no abstract]
Empirical Analysis of Stochastic Volatility Model by Hybrid Monte Carlo Algorithm
Creators: name: Takaishi, Tetsuya
Publisher: name: arXiv
Year: 2013
Subjects: subject: Computational Finance (q-fin.CP)
subject: Computational Physics (physics.comp-ph)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Economics and business
subject: FOS: Physical sciences

description: The stochastic volatility model is one of volatility models which infer latent volatility of asset returns. The Bayesian inference of the stochastic volatility (SV) model is performed by the hybrid Monte Carlo (HMC) algorithm which is superior to other Markov Chain Monte Carlo methods in sampling volatility variables. We perform the HMC simulations of the SV model for two liquid stock returns traded on the Tokyo Stock Exchange and measure the volatilities of those stock returns. Then we calculate the accuracy of the volatility measurement using the realized volatility as a proxy of the true volatility and compare the SV model with the GARCH model which is one of other volatility models. Using the accuracy calculated with the realized volatility we find that empirically the SV model performs better than the GARCH model.
description: 10 pages, 5 figures
Roles for Local Planners in Industrial Recruitment
Creators: name: Redmond, Michael
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1978

description: The economy of North Carolina has undergone many changes in the last 20 years. The large increases in employment and population are well known. The exodus of displaced farm workers to the North has ceased and many of the new jobs entering the state are higher paying than those in the traditional manufacturing base of textiles and apparel. Although North Carolina still ranks near the bottom in average manufacturing wages, state officials are optimistic about the future because of many economists' predictions of continued expansion of higher wage jobs. Officials are also encouraged by indications that new industry is locating in the poorer areas of the state, and that convergence of wages and income seems to be occurring among the different regions of the state. Despite this outlook, some areas of the state will probably continue to lag in income growth, new employment, and other aspects of economic development. In part this will be due to limitations in the state's industrial recruitment, the dominant economic development policy operating in North Carolina. This article considers the weakness of industrial recruitment and suggests ways in which it could be improved. These suggestions will involve new roles for local planners in the economic development process.
Einzel-, Doppel- und Dreifachquantenpunkte im Transport
Creators: name: Rogge, Maximilian Christoph
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2008
Subjects: subject: Gekoppelte Quantenpunkte
subject: Spinblockade
subject: Kondo-Effekt
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: [no abstract]
High-temperature superconductivity in the two-dimensional t-J model: Gutzwiller wavefunction solution
Creators: name: Kaczmarczyk, Jan
name: Buenemann, Joerg
name: Spalek, Jozef
Publisher: name: Bristol : IOP Publishing Ltd.
Year: 2014
Subjects: subject: t-J model
subject: high-temperature superconductivity
subject: Gutzwiller wave function
subject: unconventional superconductivity
subject: variational Monte-Carlo method
subject: mean-field theory
subject: dimensional fermi-surface
subject: hubbard-model
subject: state
subject: transition
subject: pseudogap
subject: oxides
subject: instability
subject: competition
subject: ansatz
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: A systematic diagrammatic expansion for Gutzwiller wavefunctions (DE-GWFs) proposed very recently is used for the description of the superconducting (SC) ground state in the two-dimensional square-lattice t–J model with the hopping electron amplitudes t (and $t^{\prime} $) between nearest (and next-nearest) neighbors. For the example of the SC state analysis we provide a detailed comparison of the methodʼs results with those of other approaches. Namely, (i) the truncated DE-GWF method reproduces the variational Monte Carlo (VMC) results and (ii) in the lowest (zeroth) order of the expansion the method can reproduce the analytical results of the standard Gutzwiller approximation (GA), as well as of the recently proposed 'grand-canonical Gutzwiller approximation' (called either GCGA or SGA). We obtain important features of the SC state. First, the SC gap at the Fermi surface resembles a ${{d}_{{{x}^{2}}-{{y}^{2}}}}$ wave only for optimally and overdoped systems, being diminished in the antinodal regions for the underdoped case in a qualitative agreement with experiment. Corrections to the gap structure are shown to arise from the longer range of the real-space pairing. Second, the nodal Fermi velocity is almost constant as a function of doping and agrees semi-quantitatively with experimental results. Third, we compare the doping dependence of the gap magnitude with experimental data. Fourth, we analyze the k-space properties of the model: Fermi surface topology and effective dispersion. The DE-GWF method opens up new perspectives for studying strongly correlated systems, as it (i) works in the thermodynamic limit, (ii) is comparable in accuracy to VMC, and (iii) has numerical complexity comparable to that of the GA (i.e., it provides the results much faster than the VMC approach).
Durchflusszytometrie in der Biotechnologie
Creators: name: Jochums, André
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2018
Subjects: subject: Durchflusszytometrie
subject: Titandioxid
subject: Nanopartikelaufnahme
subject: Zelllinienentwicklung
subject: Dewey Decimal Classification::600 | Technik::660 | Technische Chemie

description: In der vorliegenden Arbeit wurden fortgeschrittene durchflusszytometrische Methoden entwickelt und angewandt. Im ersten Teil wurde an einer Methode zur Selektion von hochproduzierenden Zelllinien gearbeitet. Diese sollte sowohl die Aptamertechnologie als auch das fluorescence- activated cell sorting (FACS) kombinieren. Die Methode basiert auf dem affinity matrix attachement und soll Kosten und Zeitaufwand der Zelllinienentwicklung drastisch senken. Dabei wurden zwei verschiedene Methoden zur Immobilisierung von Aptameren auf Zelloberflächen entwickelt und die Vor- und Nachteile aufgeführt. Es wurden die crosslinker Cyanurchlorid und BS3 (Bis(sulfosuccinimidyl)suberat) verwendet. Beide basieren auf einer Amino-Amino-Kopplung der Aptamere mit den Zellen. Die Untersuchung wurde am Beispiel des industrierelevanten Wachstumsfaktors VEGF mit Chinese Hamster Ovary (CHO) Zellen durchgeführt. Aufgrund von zellbindenden oder penetrierenden Eigenschaften zeigte sich VEGF für die Untersuchungen problematisch. Die Methode bedarf also noch weiterer Überprüfungen. Im zweiten Teil der Arbeit wurde die Aufnahme und Toxizität von Titandioxidnanopartikeln (UV100) auf zwei verschiedene Standardzelllinien (A549 und NIH-3T3) untersucht. Dabei stellte sich heraus, dass die Zelltypen die Partikel unterschiedlich schnell aufnehmen. Hierfür wurden verschiedene durchflusszytometrische Methoden zur Detektion der Aufnahme angewandt, darunter auch eine rein streulichtbasierte Methode. Die Ergebnisse zeigen, dass für eine in vitro Testung verschiedene Zelllinien herangezogen werden sollten.
G protein-coupled receptor allosterism and complexing
Creators: name: Kenakin, Terry
name: Christopoulos, Arthur
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: G protein-coupled receptors (GPCRs) represent the largest family of cell-surface receptors. These receptors are natural allosteric proteins because agonist-mediated signaling by GPCRs requires a conformational change in the receptor protein transmitted between two topographically distinct binding sites, one for the agonist and another for the G protein. It is now becoming increasingly recognized, however, that the agonist-bound GPCR can also form ternary complexes with other ligands or "accessory" proteins and display altered binding and/or signaling properties in relation to the binary agonist-receptor complex. Allosteric sites on GPCRs represent novel drug targets because allosteric modulators possess a number of theoretical advantages over classic orthosteric ligands, such as a ceiling level to the allosteric effect and a potential for greater GPCR subtype-selectivity. Because of the noncompetitive nature of allosteric phenomena, the detection and quantification of such effects often relies on a combination of equilibrium binding, nonequilibrium kinetic, and functional signaling assays. This review discusses the development and properties of allosteric receptor models for GPCRs and the detection and quantification of allosteric effects. Moreover, we provide an overview of the current knowledge regarding the location of possible allosteric sites on GPCRs and candidate endogenous allosteric modulators. Finally, we discuss the potential for allosteric effects arising from the formation of GPCR oligomers or GPCRs complexed with accessory cellular proteins. It is proposed that the study of allosteric phenomena will become of progressively greater import to the drug discovery process due to the advent of newer and more sensitive GPCR screening technologies.
Interplay between partnership formation and competition in generalized May-Leonard games
Creators: name: Roman, Ahmed
name: Dasgupta, Debanjan
name: Pleimling, Michel
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: In order to better understand the interplay of partnership and competition in population dynamics we study a family of generalized May-Leonard models with $N$ species. These models have a very rich structure, characterized by different types of space-time patterns. Interesting partnership formations emerge following the maxim that "the enemy of my enemy is my friend." In specific cases cyclic dominance within coarsening clusters yields a peculiar coarsening behavior with intriguing pattern formation. We classify the different types of dynamics through the analysis of the square of the adjacency matrix. The dependence of the population densities on emerging pattern and propagating wave fronts is elucidated through a Fourier analysis. Finally, after having identified collaborating teams, we study interface fluctuations where we initially populate different parts of the system with different teams.
description: 27 pages, 12 figures, accepted for publication in Physical Review E
Acting For Equity: [Introduction to] Planning for Equity in a Local Context: Case Studies from the North Carolina chapter of the American Planning Association Contributors
Creators: name: Hitchings, Ben
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Introduction to Planning for Equity in a Local Context: Case Studies from the North Carolina chapter of the American Planning Association Contributors. Carolina Planning regularly publishes a feature highlighting projects from members of the North Carolina Chapter of the American Planning Association (NCAPA). This year’s submissions focus on initiatives that are addressing equity issues in North Carolina communities. From case studies discussing health impact assessments to articles highlighting the importance of using data to help inform equitable planning activities and funding, these writers provide valuable insights into the important role North Carolina planners play in shaping the futures of their communities.
Saxifraga oppositifolia L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: S. oppositifolia L. Cat. 154und 426. Bis 3800 m: Weissmies, Nordgrat (Menzi 1931); bis gegen 3800 m: Matterhorn, Ostgrat (Oberson 1951). Tiefe Stellen: ausser den im Cat.426 genannten Z. B.: Chippis, 530 m (Wille); Bovernier, 620 m (J.); Ausgang des Gamsertales, 700 m (J.); Tunnetschgraben bei Mörel, 930 m (B. B. T. Z.); Gondo- Schlucht ob der Casermetta, 1110-1120m (Becherer); Bisse de Saviese, 1180 m (Mariétan). Var. distans Ser. (var. Murithiana [Tissière] Vaccari) - Verbreitet. Subvar. pseudo-Rudolphiana Engler et Irmscher (S. opp. f. conferta Beyer, S. opp. ssp. glandulifera var. Murithiana f. conferta Vaccari) - 3: Turtmanntal (Goudet). Hierher höchstwahrscheinlichauch die Angaben von S. Rudolphiana Hornschuch im Cat. 154und die späteren Angaben dieser Art aus der penninischen Kette (so noch 1929]MARIÉTAN) (vgl. Becherer Lit. 1941a, S. 331). Im italienischen Grenzgebiet am Col de Fenêtre de Ferret (F.) und Col de Fenêtre de Bagnes (VACCARI). Var. imbricata Ser. (var. typica [Vaccari] Engler et Irmscher) - 4: Rappental (B. C. W.). Im italienischen Grenzgebiet am Col de Fenêtre de Ferret (VACCARI).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
D1.1 Requirements Analysis for AI towards Addressing Security Risks and Threats to System and Network Architectures
Creators: name: AUSTRALO
Publisher: name: Zenodo
Year: 2022

description: This document is part of the first phase of the SPATIAL project, which focuses on identifying requirements and design guidelines for modern system architectures based on accountable AI. The deliverable document at hand is to be regarded as the basis for achieving these goals. Precisely, this document aims to establish a comprehensive catalogue of aspects and general design principles to be considered when integrating and utilizing AI algorithms and frameworks for addressing security risks and threats to system (and network) architectures.
The Politics of Planning A Growth Management System: The Key Ingredients For Success
Creators: name: DeGrove, John M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Florida and other states developed and implemented comprehensive growth management systems over the past twenty years. This article examines these programs and the necessary ingredients for successful implementation. These ingredients should be helpful in developing and implementing the state and regional growth management systems that are destined to develop in the 1990s.
Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome
Creators: name: Nagle, Deborah L.
name: Woolf, Elizabeth A.
name: Dussault, Barry J., Jr.
name: Perou, Charles M.
name: Karim, Mohammad A.
name: Moore, Karen J.
name: McGrail, Sonja H.
name: Bork, Peer
name: Holmgren, Lisa
name: Spritz, Richard A.
name: Duyk, Geoffrey M.
name: Boissy, Raymond E.
name: Misumi, Donald J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Chediak-Higashi syndrome (CHS) is a rare, autosomal recessive disorder characterized by hypopigmentation, severe immunologic deficiency with neutropenia and lack of natural killer (NK) cells, a bleeding tendency and neurologic abnormalities1–4. Most patients die in childhood. The CHS hallmark is the occurrence of giant inclusion bodies and organelles in a variety of cell types, and protein sorting defects into these organelles5–8. Similar abnormalities occur in the beigemouse6,7,9–13, the proposed model for human CHS. Two groups have recently reported the identification of the beige gene14,15, however the two cDNAs were not at all similar. Here we describe the sequence of a human cDNA homologous to mouse beige, identify pathologic mutations and clarify the discrepancies of the previous reports. Analysis of the CHS polypeptide demonstrates that its modular architecture is similar to the yeast vacuolar sorting protein, VPS15.
The Essence of sustainable corporate venture capital performance - essays on CVC success
Creators: name: Fischer, Daniel Matthias
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2021
Subjects: subject: Corporate Venture Capital
subject: Performance
subject: outcomes
subject: success factors
subject: survival
subject: Leistung
subject: Ergebnisse
subject: Erfolgsfaktoren
subject: Überlebensfähigkeit
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::330 | Wirtschaft

description: Corporate venture capital (CVC) is understood as equity-financed investments in young, unlisted companies. CVC is a rapidly growing phenomenon that is enjoying increasing popularity and recognition, not only in practice but also in academic research. In times of increasing pressure to innovate, companies can create CVC programs that positively impact their strategic (e.g., innovation capability) and financial performance. The historical development of CVC programs took place in several waves, each of which was accompanied by a strong upswing and an equally strong downturn. The phases of the downturn were associated with a widespread discontinuation of CVC programs as well as high write-offs on investment capital. In addition to developments in the financial and technology markets, these serious times were also due to hurdles in the structural development of CVC programs. The result of the combination of influencing factors on the survival of CVC programs was remarkable, with the average survival of CVC units sometimes being only 2.2 years (Dushnitsky, 2012). A sustainable success of CVC programs is therefore due to contextual and organizational factors. Contextual factors can be influenced to a limited extent, whereas organizational factors can be influenced easily. These organizational factors are in the focus of this dissertation. The aim of this dissertation is to identify and evaluate the interplay of key factors influencing the success of CVC programs. Due to the unique structure of these programs, the key factors are considered separately for the parent company, the CVC unit, and the portfolio companies. This is intended to contribute to the existing inconsistent view in this area. Furthermore, the above-mentioned ongoing discussion is enriched by looking at the performance of the three CVC parties separately to point out their interactions.
Entwicklung eines Aktivitätssensors für höhere Pilze bei der Terpenbiotransformation
Creators: name: Schäfer, Silvia
Publisher: name: Hannover : Universität
Year: 2004
Subjects: subject: Activity sensor
subject: oxygen consumption rate
subject: fungal biotransformation
subject: Dewey Decimal Classification::600 | Technik::660 | Technische Chemie

description: [no abstract]
Orbital-selective superconductivity, gap anisotropy and spin resonance excitations in a multiorbital t-J1-J2 model for iron pnictides
Creators: name: Yu, Rong
name: Zhu, Jian-Xin
name: Si, Qimiao
Publisher: name: arXiv
Year: 2013
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the orbital-dependent superconducting pairing in a five-orbital t-J1-J2 model for iron pnictides. Depending on the orbital selectivity of electron correlations and the orbital characters along the Fermi surface, the superconducting gap in an A_{1g} pairing state may exhibit anisotropy. This anisotropy varies with the degree of J1-J2 magnetic frustration. We have also calculated the dynamical spin susceptibility in the superconducting state. The frequency dependence of the susceptibility at the antiferromagnetic wavevector (π,0) shows a resonance, whose width is enhanced by the orbital dependence of the superconducting gap; when the latter is sufficiently strong, the resonance peak may be split into two. We discuss the implications of our results on the recent angle-resolved photoemission and neutron-scattering measurements in several superconducting iron pnictides.
description: 4.5 pages, 3 figures, with supplementary materials