cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Inhibitory Motor Control in Adults with Psychostimulant Use Disorder and Adults with Attention Deficit Hyperactivity Disorder: A Meta-analysis
Creators: name: Villafaña, Iliana Yaraset Sandoval
name: Leija, Dulce Nohemí Martínez
name: Yaira Chamorro
name: Matute, Esmeralda
name: Inozemtseva, Olga
name: Ettinger, Ulrich
name: González, Jorge Juárez
name: Maleni Mota
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Life Sciences
subject: Cognitive Neuroscience
subject: Neuroscience and Neurobiology

description: The aim of the present protocol is to characterize inhibitory motor control in adults with PUD and adults with ADHD in comparison with their controls identifying the most affected motor inhibitory control variables in each disorder, and subsequently to determine which disorder shows greater alterations. As primary variables, we will include the measures related to inhibitory control from the Stop Signal task (Stop Signal Reaction Time, SSRT, correct inhibition) and the Go/no go task (commission errors, i.e. failed inhibitions in No-go trials). Complementary measures will be classified as secondary measures (reaction time and hits on Go trials, etc.). Our analysis will focus first on obtaining the effect sizes derived from the comparison between adults with PUD and their neurotypical controls, and between ADHD adults and their respective controls. Then, we will contrast the effect sizes obtained for each disorder.
Structural characterization of essential enzymes involving sialic acid metabolism in bacterial pathogens
Creators: name: Lee, Ho Jun
Publisher: name: University of British Columbia
Year: 2010

description: Sialic acid plays vital roles in various biological processes including cellular recognition and cell adhesion. The biosynthesis and post-synthetic processing of sialic acid is particularly important to host-pathogen interactions because many virulent bacteria decorate their cell surfaces with sialic acid-containing molecules in order to evade the host’s immune response. Neisseria meningitidis, a highly invasive human pathogen that causes bacterial meningitis, produces a capsular polysaccharide comprised of polysialic acids that protect the bacteria from the host’s immune system by mimicking the sialic acid-containing cell surface structures. The biosynthesis of sialic acid is catalyzed by sialic acid synthase NeuB. We report the structural and biochemical analysis of the first potent inhibitor of sialic acid synthase from N. meningitidis. The inhibitor was synthesized as a mixture of stereoisomers, which mimics the tetrahedral intermediate of the NeuB reaction. Based on the crystallographic and kinetic analysis of the inhibitor binding, an improved mechanism is proposed. Capsular polysaccharides of certain strains of N. meningitidis can be further acetylated by sialic acid-specific O-acetyltransferases, a modification that correlates with the virulence in bacterial infection. In the second part of the thesis, we report the first kinetic and structural analysis of bacterial sialic acid O-acetyltransferase OatWY from N. meningitidis. Crystals of OatWY were obtained in complex with either CoA, acetyl-CoA, or nonhydrolyzable donor analogue S-(2-oxopropyl)-CoA. Structural analysis in combination with kinetic and mutagenesis studies elucidates the mechanistic features and substrate specificity of this enzyme. Campylobacter jejuni, a leading causative agent of bacterial diarrhea and gastroenteritis, expresses sialylated lipooligosaccharide, which mimics the carbohydrate structure of human gangliosides. Sialyltransferase Cst-II is the enzyme responsible for the lipooligosaccharide sialylation in C. jejuni as a means of evading the host's immune system. The last part of the thesis describes the first ternary complex of Cst-II with the donor analogue CMP and the terminal trisaccharide (Neu5Ac-α-2,3-Gal-β-1,3-GalNAc) of its natural acceptor. Site-directed mutagenesis of acceptor binding residues was performed and mutants were characterized by enzyme kinetics. Our results reveal the structural basis for the binding of a physiologically relevant natural acceptor and provide additional insight into the mechanism and acceptor specificity of this enzyme.
Being and Becoming an Experienced Teacher
Creators: name: Skuce, Timothy
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Education--Curriculum and Instruction
subject: Education--Philosophy of
subject: Education--Social Sciences
subject: Hermeneutics
subject: phenomenology
subject: autobiography
subject: Social Studies
subject: Gadamer
subject: experience
subject: vulnerability
subject: Teacher Identity
subject: citizenship
subject: currere curriculum

description: This thesis inquires into what it is to be and to become an experienced teacher. Although becoming an experienced teacher in part depends upon acquiring epistemological knowledge, such as instructional strategies and content knowledge, this study explores the relational qualities of experience. Drawing on the philosophical writings of Hans-Georg Gadamer and particularly his theory of Erfahrung, this thesis journeys into the existential and ontological questions that undergird the core themes of citizenship and identity stipulated in the Alberta Social Studies Program of Studies. These journeys are methodologically supported by examining inner and outer pathways including conversations, autobiographical reflections, and readings. Becoming experienced calls for teachers to embark on an existential quest with fellow travellers. This journey requires the cultivation of a pedagogical attunement that embraces the otherness of the other. Encounters with otherness may unsettle our understandings of the world and engender an inner awareness of our own historicity. Insights gained from journeys with others contribute to our capacity to responsibly respond to the particularity of the children entrusted to our care and the cultivation of discernment—ethical judgments that are reflective, intentional, and contextual. Erfahrung does not seek a fixed or final destination; rather to be and to become experienced recognizes the finitude and conditionedness of our understandings. Thus, to be and to become experienced is always on the way. Throughout this journey we are required to put our understandings at risk—honouring the vulnerability and precariousness of our factical lives. While co-venturing with others we are called upon to hear the voice of the other that occasions more fulsome understandings of others, the world and oneself. Accordingly, being an experienced teacher orients us to a radical openness, which occasions the possibility of the not yet known. This thesis culminates in five touchstones that characterize Gadamer’s theory of Erfahrung.
Additional file 4 of Reaching higher: External scapula assistance can improve upper limb function in humans with irreversible scapula alata
Creators: name: Georgarakis, Anna-Maria
name: Xiloyannis, Michele
name: Dettmers, Christian
name: Joebges, Michael
name: Wolf, Peter
name: Riener, Robert
Publisher: name: figshare
Year: 2021
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 4. Plane of Elevation Analysis.
Stellar lifetime and ultraviolet properties of the old metal-rich Galactic open cluster NGC6791: a pathway to understand the UV upturn of elliptical galaxies
Creators: name: Buzzoni, Alberto
name: Bertone, Emanuele
name: Carraro, Giovanni
name: Buson, Lucio
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The evolutionary properties of the old metal-rich Galactic open cluster NGC6791 are assessed, based on deep UB photometry and 2Mass JK data. For 4739 stars in the cluster, bolometric luminosity and effective temperature have been derived from theoretical (U-B) and (J-K) color fitting. The derived H-R diagram has been matched with the UVBLUE grid of synthetic stellar spectra to obtain the integrated SED of the system, together with a full set UV (Fanelli) and optical (Lick) narrow-band indices. The cluster appears to be a fairly good proxy of standard elliptical galaxies, although with significantly bluer infrared colors, a shallower 4000A Balmer break, and a lower Mg2 index. The confirmed presence of a dozen hot stars, along their EHB evolution, leads the cluster SED to consistently match the properties of the most active UV-upturn galaxies, with 1.7+/-0.4% of the total bolometric luminosity emitted shortward of 2500A. The cluster Helium abundance results Y=0.30 +/-0.04, while the Post-MS implied stellar lifetime from star number counts fairly agrees with the theoretical expectations from both the Padova and BASTI stellar tracks. A Post-MS fuel consumption of 0.43 +/- 0.01 M_sun is found for NGC6791 stars, in close agreement with the estimated mass of cluster He-rich white dwarfs. Such a tight figure may lead to suspect that a fraction of the cluster stellar population does actually not reach the minimum mass required to effectively ignite He in the stellar core.
description: A total of 15 pages, with 9 figures and 3 tables. The paper is to appear in the Astrophysical Journal. See http://www.bo.astro.it/~eps/home.html for further data retrieval and future track of the project
The Preferred Directions of Conjunctive Grid X Head Direction Cells in the Medial Entorhinal Cortex Are Periodically Organized
Creators: name: Keinath, Alexander Thomas
Publisher: name: University of Illinois at Chicago
Year: 2023
Subjects: Uncategorized

description: The discovery of speed-modulated grid, head direction, and conjunctive grid x head direc-tion cells in the medial entorhinal cortex has led to the hypothesis that path integration, theupdating of one’s spatial representation based on movement, may be carried out within thisregion. This hypothesis has been formalized by many computational models, including aclass known as attractor network models. While many of these models propose specificmechanisms by which path integration might occur, predictions of these specific mechanisms have not been tested. Here I derive and test a key prediction of one attractor networkpath integration mechanism. Specifically, I first demonstrate that this mechanism predicts aperiodic distribution of conjunctive cell preferred directions in order to minimize drift. Next, Itest whether conjunctive cell preferred directions are in fact periodically organized. Resultsindicate that conjunctive cells are preferentially tuned to increments of 36°, consistent withdrift minimization in this path integration mechanism. By contrast, no periodicity wasobserved in the preferred directions of either pure grid or pure head direction cells. Theseresults provide the first neural evidence of a nonuniform structure in the directional preferences of any head direction representation found in the brain.
Occupation number-based energy functional for nuclear masses
Creators: name: Bertolli, M.
name: Papenbrock, T.
name: Wild, S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We develop an energy functional with shell-model occupations as the relevant degrees of freedom and compute nuclear masses across the nuclear chart. The functional is based on Hohenberg-Kohn theory with phenomenologically motivated terms. A global fit of the 17-parameter functional to nuclear masses yields a root-mean-square deviation of χ= 1.31 MeV. Nuclear radii are computed within a model that employs the resulting occupation numbers.
Ultra-fine dark matter structure in the Solar neighbourhood
Creators: name: Fantin, Daniele S. M.
name: Green, Anne M.
name: Merrifield, Michael R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The direct detection of dark matter on Earth depends crucially on its density and its velocity distribution on a milliparsec scale. Conventional N-body simulations are unable to access this scale, making the development of other approaches necessary. In this paper, we apply the method developed in Fantin et al. 2008 to a cosmologically-based merger tree, transforming it into a useful instrument to reproduce and analyse the merger history of a Milky Way-like system. The aim of the model is to investigate the implications of any ultra-fine structure for the current and next generation of directional dark matter detectors. We find that the velocity distribution of a Milky Way-like Galaxy is almost smooth, due to the overlap of many streams of particles generated by multiple mergers. Only the merger of a 10^10 Msun analyse can generate significant features in the ultra-local velocity distribution, detectable at the resolution attainable by current experiments.
description: 9 pages, 6 figures, accepted for publication in MNRAS
Multiscale Simulation of mRNA Synthesis by RNA Polymerase II
Creators: name: Zhang, Rui
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Chemistry--Physical
subject: RNA Polymerase II

description: RNA polyermase II, a crucial enzyme for gene expression in eukaryotes, synthesizes messenger RNAs with high selectivity. Despite its importance, its selection and catalysis mechanism is not well understood. We first investigated, by a stochastic simulation algorithm, the entire nucleotide addition cycle based on an event-driven model. The results suggest that the discrimination of unmatched nucleotide mainly lies in its thermodynamic instability in the addition site, and the selectivity for the 2’-OH is from the catalytic reaction. To understand the stability of different nucleotides in the addition site on the atomistic level, we performed MD and free energy perturbation simulations, and found that mutating a cognate GTP to a non-cognate UTP in the active site costs ~16.8kcal/mol while mutating a cognate GTP to a 2’-deoxyGTP costs ~2kcal/mol. Since two binding sites exist in the enzyme, we conducted molecular dynamics and umbrella sampling calculations to simulate the entry of a cognate GTP from the entry site to the addition site. The results demonstrate that two key motifs, the trigger loop and the bridge helix, play important roles in this process. Facilitated by these two motifs, the NTP entry is a spontaneous process with an energy decrease of ~6kcal/mol. Simulation of the catalytic reaction requires a quantum mechanical/molecular mechanical (QM/MM) method to adequately describe the reaction centre and enzyme surroundings. Therefore, we reviewed QM/MM methods in the literature and implemented our own version using CHARMM and deMon2k. With this QM/MM implementation, we performed geometry optimization and MD simulations on the system at the level of DFT/MM. To speed up the calculations and cover more possible reaction pathways, we employed a specifically parametrized semiempirical method – AM1/d-PhoT for the reaction pathway search. The results reveal a proton-transfer-facilitated mechanism. While the acceptor of the initial proton transfer may vary depending on the particular conformation of the active site, all possible routes converge to the same destination. Comparison between different models shows that the role of Mg2+ (A) is more structural than catalytic.
The radial distribution of galaxies in groups and clusters
Creators: name: Budzynski, J. M.
name: Koposov, S.
name: McCarthy, I. G.
name: McGee, S. L.
name: Belokurov, V.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a new catalogue of 55,121 groups and clusters centred on Luminous Red Galaxies from SDSS DR7 in the redshift range 0.15~2.6) that is approximately a factor of two lower than that of the dark matter (as predicted by N-body cosmological simulations) and nearly independent of halo mass. Interestingly, in spite of the difference in shape between the galaxy and dark matter radial distributions, both exhibit a high degree of self-similarity. A self-consistent comparison to several recent semi-analytic models of galaxy formation indicates that: (1) beyond ~0.3 r_500 current models are able to reproduce both the shape and normalisation of the satellite profiles; and (2) within ~0.3 r_500 the predicted profiles are sensitive to the details of the satellite-BCG merger timescale calculation. The former is a direct result of the models being tuned to match the global galaxy luminosity function combined with the assumption that the satellite galaxies do not suffer significant tidal stripping, even though their surrounding dark matter haloes can be removed through this process. Combining our results with measurements of the intracluster light should provide a way to inform theoretical models on the efficacy of the tidal stripping and merging processes.
description: Resubmitted to MNRAS with minor revisions
Arc Clients User Manual For Arc 11.05 (Client Versions 1.0.0) And Above
Creators: name: Ould-Saada, Farid
Publisher: name: Zenodo
Year: 2013
Subjects: EMI

description: User Manual for ARC 11.05 (client versions 1.0.0) and above. User Manual for ARC 11.05 (client versions 1.0.0) and above
The Stellar Halos of Massive Elliptical Galaxies
Creators: name: Greene, Jenny E.
name: Murphy, Jeremy D.
name: Comerford, Julia M.
name: Gebhardt, Karl
name: Adams, Joshua J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We use the Mitchell Spectrograph (formerly VIRUS-P) on the McDonald Observatory 2.7m Harlan J. Smith Telescope to search for the chemical signatures of massive elliptical galaxy assembly. The Mitchell Spectrograph is an integral-field spectrograph with a uniquely wide field of view (107x107 sq arcsec), allowing us to achieve remarkably high signal-to-noise ratios of ~20-70 per pixel in radial bins of 2-2.5 times the effective radii of the eight galaxies in our sample. Focusing on a sample of massive elliptical galaxies with stellar velocity dispersions sigma* > 150 km/s, we study the radial dependence in the equivalent widths (EWs) of key metal absorption lines. By twice the effective radius, the Mgb EWs have dropped by ~50%, and only a weak correlation between sigma* and Mgb EW remains. The Mgb EWs at large radii are comparable to those seen in the centers of elliptical galaxies that are approximately an order of magnitude less massive. We find that the well-known metallicity gradients often observed within an effective radius continue smoothly to 2.5R_e, while the abundance ratio gradients remain flat. Much like the halo of the Milky Way, the stellar halos of our galaxies have low metallicities and high alpha-abundance ratios, as expected for very old stars formed in small stellar systems. Our observations support a picture in which the outer parts of massive elliptical galaxies are built by the accretion of much smaller systems whose star formation history was truncated at early times.
description: To appear in ApJ, 15 pages, 9 figures
On isophote curve and its characterizations
Creators: name: Dogan, Fatih
name: Yayli, Yusuf
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A04, 53A05

description: Isophote comprises a locus of the surface points whose normal vectors make a constant angle with a fixed vector. Main objective of this paper is to find the axis of an isophote curve via its Darboux frame and afterwards to give some characterizations about isophote and its axis. Particularly, for isophotes lying on a canal surface will be obtained other characterizations again.
description: 15 pages
Additional file 5 of Reaching higher: External scapula assistance can improve upper limb function in humans with irreversible scapula alata
Creators: name: Georgarakis, Anna-Maria
name: Xiloyannis, Michele
name: Dettmers, Christian
name: Joebges, Michael
name: Wolf, Peter
name: Riener, Robert
Publisher: name: figshare
Year: 2021
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 5. Supplementary Results.
Geomechanical Aspects of CO2 Storage under Fracturing and Thermal Conditions
Creators: name: Goodarzi, Somayeh
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Engineering--Chemical
subject: Engineering--Environmental
subject: Engineering--Petroleum
subject: Fracture modeling
subject: Geomechanics
subject: CO2 storage

description: One of the most important concerns with respect to the long term CO2 storage is that stress changes caused by injection could lead to spontaneous fracturing or reactivation of fracture networks which could potentially provide pathways for CO2 migration through previously impermeable rocks. For a rigorous study of the process, a coupled flow and geomechanical model of the formation should be employed and must be improved for the purpose of accurately predicting the location and shape of an induced fracture. The main purpose of this work is to i) improve the modeling technique for fracture propagation within a coupled flow and geomechanical model, ii) model and design injection schemes for CO2 sequestration projects considering the associated geomechanical mechanisms, for different geological settings, and iii) investigate the caprock integrity under upward fracture propagation with this model. Studying the thermal issues of CO2 injection and the effects of injection temperature on fracture pressure, injectivity and the pace of fracture propagation is also included in this work. Our results show that injection above the fracture pressure will have the potential to increase the well injectivity but also the possibility of fracturing the caprock. The degree of vertical propagation will strongly depend on the caprock stress state, mechanical properties and temperature changes. Injection capacity with cold CO2 injection could be significantly lower than expected, and it may be impractical to avoid induced fracture development. At small enough injection rates, fracture propagation is controlled primarily by the injection temperature, and is accelerated as injection temperature decreases. As a result, spontaneous fracturing is expected to take place in most CO2 storage projects in vertical wells with injection temperature below reservoir temperature, unless the injection rates are impractically low. This is an important finding which will also have consequences for caprock integrity. The final contribution of this work is the development of a method for improving the estimation of fracture length and development of a simplified algorithm capable of tracking the position of fracture tip on a sub-grid scale. The proposed simplified method improves the prediction of the fracture length based on estimation of tip position in a fixed grid block.
Thermal Effects Literature Review for Hudson River Representative Important Species
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1978

description: This report provides a review of the existing thermal effects literature for selected fish and invertebrates designated by the United States Environmental Protection Agency (U.S. EPA) as representative important species (RIS) for the Hudson River that should be addressed by studies to determine the effects of power plant thermal discharges on biological communities.
НАГРАДА ЗА СЛУЖЕНИЕ ГОСПОДУ
Creators: name: Груздев Денис Владиславович
name: Колосов Сергей Леонтьевич
name: Володченков Михаил Иванович
name: Кавинский Вениамин Витальевич
Publisher: name: Проблемы науки
Year: 2022
Subjects: Священное Писание Ветхого и Нового Завета (Библия)
история Церкви.

description: в статье подробно исследуется и доказывается обязательность Божьего благословения тем, кто трудится для славы Божией. Доказательство представлено примерами деятельности трёх персонажей из Священного Писания Нового Завета Канонической Синодальной Библии в русском переводе: фарисея Никодима, члена Синедриона Иосифа из Аримафеи и уважаемого законоучителя — фарисея Гамалиила. Данное исследование проведено библейским методом — «доказательство Писаниями».
Preservice Teacher Mentoring as Development for Teacher Instructional Leadership
Creators: name: Law, Justina Ka-Wai
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Education--Secondary
subject: Education--Teacher Training
subject: cooperating teacher
subject: mentoring
subject: preservice teacher
subject: teacher instructional leadership
subject: Teacher Professional Development
subject: partner teacher
subject: student teacher

description: Most of the scholarly literature concerning teacher preparation focuses on preservice teachers, which overlooks the role and perceptions of cooperating teachers. This study examined the preservice teacher mentoring experience as professional development for the cooperating teacher, specifically as a form of engaging in teacher instructional leadership. A qualitative research approach was used to examine which aspects of professional growth cooperating teachers feel are influenced through their cooperating teacher activities. The purpose of this qualitative study was to investigate the professional development benefits of serving as a cooperating teacher from the perspective of cooperating teachers. It specifically investigated cooperating teachers’ views of teacher instructional leadership and how leadership skills are facilitated through the mentorship of preservice teachers. This study contributes to a small body of literature regarding cooperating teachers and their professional development. Results suggest that serving as cooperating teachers can have a profound impact on teachers’ professional growth and instructional leadership capacity. Three main categories developed as areas in which positive growth occurred for cooperating teachers. They are: 1) Personal characteristics, 2) Pedagogical skills, and 3) Knowledge. Five major themes emerged from the data collected for this study. These themes describe the ways in which the cooperating teachers felt that their professional development was affected by serving as cooperating teachers throughout all of the knowledge, skills, and attributes (KSAs) as described by Alberta Education (1997). They are: 1) Reflection, 2) Articulation of teaching practices, 3) Collaboration and shared problem solving, 4) New ideas/strategies, 5) Meaningful conversations. Implications of the study and recommendations for practice are offered within the discussion. Keywords and concepts: Cooperating teacher, mentoring, preservice teacher, teacher instructional leadership, professional development, partner teacher, student teacher
Area law of the entropy in the critical gravity
Creators: name: Son, Edwin J.
name: Eune, Myungseok
name: Kim, Wontae
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The entropy of the Schwarzschild-anti de Sitter black hole in the recently proposed four-dimensional critical gravity is trivial in the Euclidean action formulation, while it is expressed by the area law in terms of the brick wall method given by 't Hooft. To resolve this issue, we relate the Euclidean action formulation to the brick wall method semiclassically, and show that the entropy of the black hole can be expressed by the area law at the critical point.
description: 13 pages
Intelligent Automated Diagnosis of Client Device Bottlenecks in Private Clouds
Creators: name: Widanapathirana, C.
name: Li, J.
name: Sekercioglu, Y. A.
name: Ivanovich, M.
name: Fitzpatrick, P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: We present an automated solution for rapid diagnosis of client device problems in private cloud environments: the Intelligent Automated Client Diagnostic (IACD) system. Clients are diagnosed with the aid of Transmission Control Protocol (TCP) packet traces, by (i) observation of anomalous artifacts occurring as a result of each fault and (ii) subsequent use of the inference capabilities of soft-margin Support Vector Machine (SVM) classifiers. The IACD system features a modular design and is extendible to new faults, with detection capability unaffected by the TCP variant used at the client. Experimental evaluation of the IACD system in a controlled environment demonstrated an overall diagnostic accuracy of 98%.
description: 2011 Fourth IEEE International Conference on Utility and Cloud Computing (UCC)
The Effects of Fluoxetine Treatment Following Injury of Medial Frontal Cortex in Mice
Creators: name: McAllister, Brendan
Publisher: name: Graduate Studies
Year: 2014
Subjects: subject: Neuroscience
subject: Fluoxetine
subject: Medial frontal cortex
subject: Mice
subject: Brain injury

description: The drug fluoxetine has been found to have protective properties when administered following brain injury. However, its potential to promote behavioural recovery and the mechanisms by which it might do so require further characterization. To this end, the effects of four weeks of post-injury fluoxetine treatment were examined in mice, using medial frontal cortex (MFC) aspiration lesions as a model of cortical injury. A battery of behavioural tests dependent on MFC function was conducted. MFC lesions reduced locomotion in several tests, decreased anxiety-like behaviour, and impaired contextual association memory. Fluoxetine treatment did not alter the observed hypolocomotion or anxiolysis, but it may have reduced the cognitive impairment. In addition, fluoxetine treatment increased the social dominance of the mice with MFC lesions. These benefits of fluoxetine treatment did not appear to depend on the increased survival of cells born one week after injury or on the induction of hypothermia.
Calibration of Multi-Sensor Laser Scanning Systems
Creators: name: Hassan, Essam
Publisher: name: Graduate Studies
Year: 2014
Subjects: subject: Engineering--Electronics and Electrical
subject: Laser Scanning, LiDAR, Calibration

description: Over the past few years, LiDAR or laser scanning systems (airborne, static and terrestrial mobile mapping systems) are considered as well-accepted technologies that can quickly acquire precise 3D point clouds of the terrain surfaces. On the functional level, any mobile system could be defined as an integration of several subsystems such as: Global Positioning System (GPS), an Inertial Navigation System (INS), and the laser scanner. To ensure the geometric quality of the collected point cloud, LiDAR systems should undergo a rigorous calibration procedure. LiDAR system calibration comprises individual sensor calibration (i.e., laser ranging and scanning unit) and mounting parameters calibration (i.e., lever arm offset and boresight angles) relating the system components such as the GPS, INS, and laser scanner. In this research work, a new method for automatic selection of suitable overlapping strip pairs/regions for optimized LiDAR system calibration is introduced. The experimental results have shown that the quality of the estimated parameters using the automatic selection is quite similar to the estimated parameters using the manual selection while the processing time of automatic selection is 3 times faster than the manual selection. In the field of surveying and mapping in recent years, the development of airborne LiDAR systems is characterized by the use of multiple laser scanners for accurate and efficient capture of 3D data along ground and above ground features. In this research, new calibration procedure for dealing with airborne multi-laser scanning systems is presented. The experimental results have shown that accurate estimation of the calibration parameters of each laser scanner can be obtained using the proposed method. Terrestrial mobile laser scanning (TMLS) is the latest approach towards fast and cost-effective acquisition of 3-dimensional spatial data. Accurately evaluating the intrinsic and mounting parameters of TMLS systems is an obvious necessity. However, available systems on the market may lack suitable and efficient practical workflows on how to perform this calibration. This research introduces an innovative method for accurately determining the intrinsic and mounting parameters of multi-TMLS systems. The proposed calibration method investigates a two-step (indoor followed by outdoor) calibration procedure for calibrating terrestrial mobile multi-laser scanning systems. In this research work, a simulation program is developed for generating 3D LiDAR data such as a Velodyne-based Mobile laser scanning system (HDL-32E). The experimental results are performed using a simulated dataset for investigating the one-step and two-step calibration procedures. The experimental results have shown that the estimated parameters using the two-step calibration procedure are better than the estimated parameters derived from the one-step calibration procedure.
A novel wireless three-pad ECG system for generating conventional 12-lead signals
Creators: name: Cao, Huasong
Publisher: name: University of British Columbia
Year: 2010

description: A wireless body area network (WBAN) is a radio-frequency (RF) based wireless networking technology that interconnects tiny nodes in, on or around a human body. Typically, the transmissions of these nodes cover a short range of about 2 meters. This thesis presents a complete survey on recent advances in WBAN, including the market needs, channel modeling, standardization of low-layer communication protocols, quality-of-service (QoS) provisions, developments of sensors/actuators, WBAN architectures and experimental platforms. A recent work employing the nonbeacon-enabled mode of the IEEE 802.15.4 standard for QoS provisions has motivated us to design a QoS framework based on the beacon-enabled mode of the same standard. The proposed QoS framework can better differentiate WBAN application traffic streams and serve periodic traffic more directly through the time-division-multiple-access (TDMA) based mechanism. A dominant feature of the proposed framework is the minimum adaptation to the existing standard, which makes it easy to adopt our platform and associated algorithms, as well as to implement them on off-the-shelf hardware platforms. Employing the proposed QoS framework, we propose a novel wireless three-pad electrocardiography (W3ECG) system. W3ECG furthers the pad design idea of single-pad wireless ECG systems. Inspired by the transformation possibility of signals obtained in vectorcardiographic (VCG) systems, we bring two more pads to the single-pad approach to gain spatial variety of the heart activity. Signals obtained from these three pads, plus the spatial information, make it possible to synthesize conventional 12-lead ECG signals. We have been able to manufacture the front-end ECG circuit, and combine it with an IEEE 802.15.4 hardware platform TelosB. Software for the server and pad has also been developed to make a fully running W3ECG possible. By explaining and evaluating our QoS platform designed for general WBAN applications, and our W3ECG system invented for particular healthcare area, we foresee a bright future for wide deployments of such kind of wireless networks on the human body.
A BPS Skyrme model
Creators: name: Adam, C.
name: Sanchez-Guillen, J.
name: Wereszczynski, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Within the set of generalized Skyrme models, we identify a submodel which has both infinitely many symmetries and a Bogomolny bound which is saturated by infinitely many exact soliton solutions. Concretely, the submodel consists of the square of the baryon current and a potential term only. Further, already on the classical level, this BPS Skyrme model reproduces some features of the liquid drop model of nuclei. Here, we review the properties of the model and we discuss the semiclassical quantization of the simplest Skyrmion (the nucleon).
description: Conference Proceedings of the 28th International Colloquium On Group Theoretical Methods In Physics (GROUP 28), July 2010, Northumbria, England. 10pages, 1 figure. Version 2: Publication information added
Investigating the properties of AGN feedback in hot atmospheres triggered by cooling-induced gravitational collapse
Creators: name: Pope, Edward C. D.
name: Mendel, J. Trevor
name: Shabala, Stanislav S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Radiative cooling may plausibly cause hot gas in the centre of a massive galaxy, or galaxy cluster, to become gravitationally unstable. The subsequent collapse of this gas on a dynamical timescale can provide an abundant source of fuel for AGN heating and star formation. Thus, this mechanism provides a way to link the AGN accretion rate to the global properties of an ambient cooling flow, but without the implicit assumption that the accreted material must have flowed onto the black hole from 10s of kiloparsecs away. It is shown that a fuelling mechanism of this sort naturally leads to a close balance between AGN heating and the radiative cooling rate of the hot, X-ray emitting halo. Furthermore, AGN powered by cooling-induced gravitational instability would exhibit characteristic duty cycles (delta) which are redolent of recent observational findings: delta is proportional to L_X/sigma_{*}^{3}, where L_X is the X-ray luminosity of the hot atmosphere, and sigma_{*} is the central stellar velocity dispersion of the host galaxy. Combining this result with well-known scaling relations, we deduce a duty cycle for radio AGN in elliptical galaxies that is approximately proportional to M_{BH}^{1.5}, where M_{BH} is the central black hole mass. Outburst durations and Eddington ratios are also given. Based on the results of this study, we conclude that gravitational instability could provide an important mechanism for supplying fuel to AGN in massive galaxies and clusters, and warrants further investigation.
description: Accepted for publication in MNRAS. 8 pages
Preventive Health Care among Canadian Adults with Schizophrenia and Related Disorders
Creators: name: Beck, Cynthia Anita
Publisher: name: Graduate Studies
Year: 2014
Subjects: subject: Epidemiology
subject: Medicine and Surgery
subject: Mental Health
subject: schizophrenia
subject: coronary disease
subject: risk factor
subject: metabolic syndrome
subject: preventive health services
subject: hypertension
subject: smoking
subject: cholesterol
subject: Diabetes
subject: Obesity
subject: Epidemiology
subject: Health services
subject: mental disorder

description: Objective: To characterize cardiovascular disease risk factors (CVD-RFs) and preventive health services of people with schizophrenia and related disorders (SCZ) in a Canadian context. Methods: This cross-sectional survey collected laboratory, physical examination, and interview data from 202 randomly selected Calgary outpatients with SCZ. Results: There were high prevalences of several CVD-RFs. Metabolic syndrome was present in 30.0%. Mean 10-year general CVD risk was 8.8%. Many previously known CVD-RFs were inadequately treated, and several previously undetected CVD-RFs were discovered (e.g. 33.3% of diabetes). There was variable receipt of preventive services, and participants explained non-receipt by “Thought it was unnecessary” or “Didn’t get around to it”. Interpretation: This study found substantial physical morbidity coupled with gaps in prevention, detection, and management, as well as patient factors that might be a target of interventions for improved care. Multifaceted strategies will be needed to make a difference in the health of people with schizophrenia.
Diamond formation beneath the Coromandel area, southwestern São Francisco Craton – The role of re-fertilization and subduction
Creators: Carvalho, Luísa D.V.
Stachel, Thomas
Pearson, D. Graham
Fuck, Reinhardt A.
Jalowitzki, Tiago
Timmerman, Suzette
Steele-Maclnnis, Matthew
Gonçalves, Guilherme O.
Pereira, Rogério Silvestre
Scholz, Ricardo
Publisher: name: University of Alberta Library
Year: 2022

Abstract

The lithospheric mantle underpinning the Alto Paranaíba Igneous Province, southwestern São Francisco Craton, was investigated through a study of 82 diamonds and their mineral inclusions from the Coromandel (Douradinho River), Verde River (northern Coromandel), Abaeté, Frutal, and Romaria deposits. Mineral inclusion abundances show that lherzolite is the main diamond source-rock, followed by eclogite, harzburgite and minor websterite. The limited chemical depletion recorded in lherzolitic inclusions suggests a post-Archean origin or modification of the lithospheric mantle beneath this part of the São Francisco craton. Sinusoidal rare earth element patterns for lherzolitic garnet inclusions indicate variable but overall low degrees of metasomatism by fluids or silico‑carbonatitic (proto-kimberlitic) melts. These results contrast with previous studies on mineral inclusions in diamonds (Canastra range, southern Coromandel; Rio da Prata system, northeastern Coromandel; our new data on the Frutal area, southwestern Coromandel), where a dominance of harzburgitic inclusions documents a more depleted, likely Archean, cratonic root. Bulk rock compositions reconstructed from eclogitic and websteritic inclusions establish a clear link between subduction processes and diamond formation in the Coromandel region. Calculated bulk rare earth element patterns match typical sections of upper oceanic crust, where plagioclase accumulation is uncommon. Pyroxene inclusion-based geothermobarometry indicates that lherzolitic and websteritic diamonds formed and last resided along a ∼ 39 mW/m2 model geotherm. Projection of eclogitic garnet-clinopyroxene pairs onto this 39 mW/m2 geotherm places their origin near the base of the lithosphere (> 180 km depth). Low nitrogen contents and high aggregation states (up to 100 %B) indicate that eclogitic, websteritic, and part of the lherzolitic diamond populations experienced extended (2.0 Byr) mantle residence at high temperatures (> 1200 °C). The similarity in mantle residence temperatures and the shared presence of minor negative Eu anomalies for eclogitic and websteritic diamonds and their inclusions may be indicative of a common origin, following emplacement of subducted oceanic crust beneath the São Francisco Craton margin likely during a Paleoproterozoic orogeny (2.2–1.9 Ga). Based on our results, future exploration efforts in the Alto Paranaíba region should shift their focus from harzburgitic to lherzolitic and eclogitic indicator minerals to find new diamond deposits and kimberlites in this area.
MODELING A PROGNOSTIC PROGRAM FOR PATIENTS WITH HORMONE-RESISTANT PROSTATE CANCER
Creators: name: Iskandarov, J.M.
name: Boyko, E.B.
name: Hasanov, Sh.T.
name: Yusupov, Sh.H.
Publisher: name: Zenodo
Year: 2023

description: Hormonal tumor resistance in some patients with prostate cancer is determined immediately from the start of treatment, while in others it develops after several months of successful treatment with hormonal therapy. Despite this, there are still no characteristic signs or reliable criteria for determining primary and secondary forms of hormonal resistance, which makes it difficult to choose adequate therapy for each patient with prostate cancer.
Emergent electromagnetism in solids
Creators: name: Nagaosa, Naoto
name: Tokura, Yoshinori
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Electromagnetic field (EMF) is the most fundamental field in condensed-matter physics. Interaction between electrons, electron-ion interaction, and ion-ion interaction are all of the electromagnetic origin, while the other 3 fundamental forces, i.e., gravitational force, weak and strong interactions are irrelevant in the energy/length scales of condensed-matter physics. Also the physical properties of condensed-matters such as transport, optical, magnetic and dielectric properties, are almost described as their electromagnetic responses. In addition to this EMF in the low energy sector, it often happens that the gauge fields appear as the emergent phenomenon due to the projection of the electronic wavefunctions onto the curved manifold of the Hilbert sub-space. These emergent electromagnetic fields (EEMF's) play important roles in many places in condensed-matter physics including the quantum Hall effect, strongly correlated electrons, and also in non-interacting electron systems. In this article, we describe its fundamental idea and some of the applications recently studied.
description: 26 pages, 12 figures, To appear in Proceedings of the Nobel Symposium on Graphene
Relationship between Blood Pressures and Brain Volumes: Systematic Review and Analysis of A Canadian Population-Based Study
Creators: name: Batool, Saima
Publisher: name: Graduate Studies
Year: 2014
Subjects: subject: Biophysics--Medical
subject: hypertension
subject: Brain Volume

description: Long-standing hypertension has been associated with global and regional brain atrophy. Little is known regarding the timing of atrophy onset and its relationship with duration and severity of hypertension. A systematic literature review was performed to identify the relationships between hypertension and brain atrophy measured using neuroimaging, to summarize the existing knowledge and to identify areas for future investigation. Most studies identified that higher systolic blood pressure was associated with late-life brain atrophy; however, these studies did not include a concurrent assessment of brain imaging in mid-life, and participants in these studies were middle-aged in the 1980s when definitions of blood pressure (BP) were more permissive and population BP control was poorer. To investigate the relationship between BP and brain atrophy in mid-life in a contemporary cohort, brain magnetic resonance (MR) images were analyzed in 778 individuals participating in the population-based PURE-MIND study, a sub-study of the international Prospective Urban Rural Epidemiologic (PURE) Study designed to identify the risk factors for common non-communicable diseases. MR data were processed for global and regional brain volumes and cortical thickness. No significant association was seen between brain volume and hypertension, after controlling for age and gender. However, few participants had markedly elevated BP, probably due to improving population-wide control of hypertension due to lower thresholds for successful treatment than in past decades. Analysis showed that brain atrophy is not a common consequence of mid-life hypertension in today’s Canadians. It is possible that aggressive screening and control of mid-life BP might prevent atrophic changes.