cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The distracted robot: what happens when artificial agents behave like us
Creators: name: GHIGLINO, DAVIDE
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: In everyday life, we are frequently exposed to different smart technologies. From our smartphones to avatars in computer games, and soon perhaps humanoid robots, we are surrounded by artificial agents created to interact with us. Already during the design phase of an artificial agent, engineers often endow it with functions aimed to promote the interaction and engagement with it, ranging from its ?communicative? abilities to the movements it produces. Still, whether an artificial agent that can behave like a human could boost the spontaneity and naturalness of interaction is still an open question. Even during the interaction with conspecifics, humans rely partially on motion cues when they need to infer the mental states underpinning behavior. Similar processes may be activated during the interaction with embodied artificial agents, such as humanoid robots. At the same time, a humanoid robot that can faithfully reproduce human-like behavior may undermine the interaction, causing a shift in attribution: from being endearing to being uncanny. Furthermore, it is still not clear whether individual biases and prior knowledge related to artificial agents can override perceptual evidence of human-like traits.
A relatively new area of research emerged in the context of investigating individuals? reactions towards robots, widely referred to as Human-Robot Interaction (HRI). HRI is a multidisciplinary community that comprises psychologists, neuroscientists, philosophers as well as roboticists, and engineers. However, HRI research has been often based on explicit measures (i.e. self-report questionnaires, a-posteriori interviews), while more implicit social cognitive processes that are elicited during the interaction with artificial agents took second place behind more qualitative and anecdotal results. The present work aims to demonstrate the usefulness of combining the systematic approach of cognitive neuroscience with HRI paradigms to further investigate social cognition processes evoked by artificial agents.
Thus, this thesis aimed at exploring human sensitivity to anthropomorphic characteristics of a humanoid robot's (i.e. iCub robot) behavior, based on motion cues, under different conditions of prior knowledge. To meet this aim, we manipulated the human-likeness of the behaviors displayed by the robot and the explicitness of instructions provided to the participants, in both screen-based and real-time interaction scenarios. Furthermore, we explored some of the individual differences that affect general attitudes towards robots, and the attribution of human-likeness consequently.
Unlocking Uzbekistan's Economic Growth Through Sustainable Tourism Development: a Strategic Perspective on Sustainable Tourism
Creators: name: Sobirov, Bobur
Publisher: name: Zenodo
Year: 2025

description: Dipresentasikan oleh Sobirov Bobur Baxtishodovich, Ph.D. dalam kegiatan 2nd WCU International Conference in Collaboration with Faculty of Law, Mahasaraswati University Denpasar on Sustainable Development dengan topik "Unlocking Uzbekistan's Economic Growth Through Sustainable Tourism Development: a Strategic Perspective on Sustainable Tourism" pada Senin, 21 April 2025 melalui Zoom Relawan Jurnal Indonesia.
Additional file 3 of SOFA in sepsis: with or without GCS
Creators: name: Wang, Lu
name: Ma, Xudong
name: Zhou, Guanghua
name: Gao, Sifa
name: Pan, Wei
name: Chen, Jieqing
name: Su, Longxiang
name: He, Huaiwu
name: Long, Yun
name: Yin, Zhi
name: Shu, Ting
name: Zhou, Xiang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Additional file 3: Table S1. Basic information of patients with sepsis in eICU database.
sj-docx-1-psp-10.1177_01461672231159767 – Supplemental material for Do Beliefs That Older Adults Are Inflexible Serve as a Barrier to Racial Equality?
Creators: name: Chaney, Kimberly E.
name: Chasteen, Alison L.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-psp-10.1177_01461672231159767 for Do Beliefs That Older Adults Are Inflexible Serve as a Barrier to Racial Equality? by Kimberly E. Chaney and Alison L. Chasteen in Personality and Social Psychology Bulletin
Numerical/Experimental Hybrid Approach to Predict Substrate Warpage
Creators: name: Kim, Byung Yub
Publisher: name: Digital Repository at the University of Maryland
Year: 2018
Subjects: subject: Mechanical engineering
subject: FOS: Mechanical engineering
subject: hybrid substrate model
subject: O/DFM
subject: shadow moiré
subject: SM-NT
subject: trace mapping

description: A hybrid approach is proposed to enhance warpage predictability of thin advanced substrates.  Experimental warpage data of thin advanced substrates is first obtained under various conditions.  High sensitivity measurements (a contour interval of 6.25 microns/fringe or equivalent to shadow moiré with a grating of 160 lines/mm) without painting the surface becomes possible through the advanced shadow moiré method called Shadow Moiré with Non-zero Talbot distance (SM-NT) in conjunction with the optical/digital fringe multiplication (O/DFM) method.  The measured warpage is combined with an FEA approach called trace mapping to incorporate the effect of the copper trace layouts into the analysis.  A hybrid model is created through calibration of the properties most critical to warpage, and the warpage values of the substrates at reflow temperatures are predicted.
Additional file 1 of Electricity mix from renewable energies can avoid further fragmentation of African rivers
Creators: name: Peters, Rebecca
name: Berlekamp, Jürgen
name: Tockner, Klement
name: Zarfl, Christiane
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Supplementary Material 1.
sj-docx-1-ahd-10.1177_00914150231196093 - Supplemental material for Disability Among Older Immigrants in the United States: Exploring Differences by Region of Origin and Gender
Creators: name: Burns, Shane D.
name: Baker, Elizabeth H.
name: Sheehan, Connor M.
name: Markides, Kyriakos S.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Geriatrics and Gerontology

description: Supplemental material, sj-docx-1-ahd-10.1177_00914150231196093 for Disability Among Older Immigrants in the United States: Exploring Differences by Region of Origin and Gender by Shane D. Burns, Elizabeth H. Baker, Connor M. Sheehan and Kyriakos S. Markides in The International Journal of Aging and Human Development
sj-docx-1-jic-10.1177_08850666231195755 - Supplemental material for Kidney Increase Natriuresis but Not Glomerular Filtration Under Veno-venous ECMO, a Retrospective Study
Creators: name: Penaud, Victor
name: Duburcq, Thibault
name: Bureau, Côme
name: Salmon Gandonnière, Charlotte
name: Arrestier, Romain
name: Henri, Samuel
name: Dres, Martin
name: Jacquier, Sophie
name: Prost, Nicolas De
name: Giraud, Raphael
name: Ricard, Jean-Damien
name: Roux, Damien
name: Uhel, Fabrice
name: Legouis, David
name: Verney, Charles
Publisher: name: SAGE Journals
Year: 2023
Subjects: Emergency Medicine
Aged Health Care
Respiratory Diseases

description: Supplemental material, sj-docx-1-jic-10.1177_08850666231195755 for Kidney Increase Natriuresis but Not Glomerular Filtration Under Veno-venous ECMO, a Retrospective Study by Victor Penaud, Thibault Duburcq, Côme Bureau and
Charlotte Salmon Gandonnière, Romain Arrestier, Samuel Henri, Martin Dres, Sophie Jacquier, Nicolas De Prost, Raphael Giraud, Jean-Damien Ricard, Damien Roux, Fabrice Uhel, David Legouis, Charles Verney in Journal of Intensive Care Medicine
Similarity reasoning for local surface analysis and recognition
Creators: name: MOSCOSO THOMPSON, ELIA
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: This thesis addresses the similarity assessment of digital shapes, contributing to the analysis of surface characteristics that are independent of the global shape but are crucial to identify a model as belonging to the same manufacture, the same origin/culture or the same typology (color, common decorations, common feature elements, compatible style elements, etc.). To face this problem, the interpretation of the local surface properties is crucial.

We go beyond the retrieval of models or surface patches in a collection of models, facing the recognition of geometric patterns across digital models with different overall shape. To address this challenging problem, the use of both engineered and learning-based descriptions are investigated, building one of the first contributions towards the localization and identification of geometric patterns on digital surfaces. Finally, the recognition of patterns adds a further perspective in the exploration of (large) 3D data collections, especially in the cultural heritage domain.

Our work contributes to the definition of methods able to locally characterize the geometric and colorimetric surface decorations. Moreover, we showcase our benchmarking activity carried out in recent years on the identification of geometric features and the retrieval of digital models completely characterized by geometric or colorimetric patterns.
Damage assessment of churches exposed to slope displacements in sliding areas
Creators: name: CAMBIAGGI, LUDOVICA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: Protecting cultural heritage from water-soil interaction related threats is a current issue and the prediction of the effects of slope displacements on buildings is very challenging. The achievement of this goal is not straightforward since it usually requires high costs due to the great amount of data to be collected for setting up reliable forecasting models. Among these threats, slow moving landslides are considered in this research, because also small slope movements can seriously affect existing structures and cause damages. In this regard, the aim is to develop a simple but effective procedure to correlate the potential damage caused to soil displacements to the slope safety conditions, represented by an ?intensity parameter? such as the slope safety factor. Churches located in, or close to, landslide areas, have been chosen as exposed structures: this choice makes the theme more challenging for the structural and geometric complexities of these particular historic buildings. Furthermore, while modelling and estimating the effects induced by deep excavations or tunnelling on existing buildings are known and widely treated geotechnical problems, the assessment of the damage caused by landslide movement has not been fully developed and only limited material exists in the literature.
The procedure developed and proposed in the Thesis takes into account:
i) identification and characterization of the exposed elements;
ii) assessment of displacements and associated strain level components caused by slope movement via numerical analyses;
iii) iii) proposal and assessment of an intensity parameter representative of deformations and stability conditions;
iv) iv) assessment of damage severity levels and develop of fragility curves,
v) v) validation of the proposed approach.
title: W N McClean hydrometric data collection
Creators: name: Black, Andrew
name: McClean, William Newsam
name: Bachell, Alasdair
name: Brown, Caroline
name: Werrity, Alan
Publisher: name: University of Dundee
publisherIdentifier: https://ror.org/03h2bxq36
publisherIdentifierScheme: ROR
Year: 2024
Subjects: classificationCode: 1.5
subject: FOS: Earth and related environmental sciences

description: Beginning in 1912, William Newsam McClean commenced a survey of the river levels and flows, loch levels, and rainfall inputs of the Inverness-shire River Garry catchment in Scotland, later expanding to the whole of the Ness basin, and the adjacent catchments of the Rivers Lochy, Spey and Aberdeenshire Dee.  McClean disseminated the results of his survey through articles published by the Institution of Water Engineers, the Royal Meteorological Society and the Royal Geographical Society, as well as through privately publishing richly-illustrated quarterly and other reports of his monitoring programme.

An extensive collection of McClean’s papers has been held in the University of Dundee Archives since 1997.  Given their value to studies of hydrology and environmental change, time series of McClean’s measurements and calculations are being published online to enhance access and promote utilisation, in line with McClean’s commitment to publishing during the operation of his organisation River Flow Records.
Time series of water levels, river flows and rainfall are being published in digital records linked from this record.  Future publications of time series, journal articles and other digital objects will be linked to this central record and will be discoverable via digital object identifiers.

Access to the archive of McClean papers may be arranged via University of Dundee Archives - see https://www.dundee.ac.uk/archives
Kutschera, Franz von, Der Weg der westlichen Philosophie
Creators: name: Kutschera, Franz Von
name: Ollig, Hans-Ludwig
Publisher: name: Theologie und Philosophie
Year: 1970

description: Theologie und Philosophie, Bd. 95 Nr. 3 (2020): Theologie und Philosophie, Band 95, Heft 3
Evolution of cooperation in spatio-temporal evolutionary games with public goods feedback
Creators: Cheng, Haihui
Sysoeva, Liubov
Wang, Hao
Yuan, Hairui
Zhang, Tonghua
Meng, Xinzhu
Publisher: name: University of Alberta Library
Year: 2024

Abstract

(description taken from article)

In biology, evolutionary game-theoretical models often arise in which players’ strategies impact the state of the environment, driving feedback between strategy and the surroundings. In this case, cooperative interactions can be applied to studying ecological systems, animal or microorganism populations, and cells producing or actively extracting a growth resource from their environment. We consider the framework of eco-evolutionary game theory with replicator dynamics and growth-limiting public goods extracted by population members from some external source. It is known that the two sub-populations of cooperators and defectors can develop spatio-temporal patterns that enable long-term coexistence in the shared environment. To investigate this phenomenon and unveil the mechanisms that sustain cooperation, we analyze two eco-evolutionary models: a well-mixed environment and a heterogeneous model with spatial diffusion. In the latter, we integrate spatial diffusion into replicator dynamics. Our findings reveal rich strategy dynamics, including bistability and bifurcations, in the temporal system and spatial stability, as well as Turing instability, Turing-Hopf bifurcations, and chaos in the diffusion system. The results indicate that effective mechanisms to promote cooperation include increasing the player density, decreasing the relative timescale, controlling the density of initial cooperators, improving the diffusion rate of the public goods, lowering the diffusion rate of the cooperators, and enhancing the payoffs to the cooperators. We provide the conditions for the existence, stability, and occurrence of bifurcations in both systems. Our analysis can be applied to dynamic phenomena in fields as diverse as human decision-making, microorganism growth factors secretion, and group hunting.
title: "Il ritorno del figliol prodigo", Barbieri Giovan Francesco detto Guercino, inv. 042 (ITA/EN)
title: Scheda catalogo digitale Borghese
titleType: AlternativeTitle
Creators: name: Iommelli, Antonio
name: Galleria Borghese
Publisher: name: Galleria Borghese
Year: 2024

description: Pubblicazione delle schede delle opere conservate nel museo ed estratte dal catalogo digitale di Galleria Borghese, nelle due versioni esistenti online, in italiano e inglese.

Collegamento al catalogo digitale:

ITA: https://www.collezionegalleriaborghese.it/

EN: https://www.collezionegalleriaborghese.it/en
THE NATURE OF NURSING PRACTICE IN POSITIVE LAW IN INDONESIA
Creators: name: SUARJANA
name: GALANG ASMARA
name: KURNIAWAN
name: SUDIARTO
Publisher: name: Zenodo
Year: 2024
Subjects: Nature, Nursing, Indonesian Law.

description: Abstract

The purpose of this study is to find the nature of Nursing Practice in Indonesia. This study is a normative legal research, namely research conducted on legal principles, legal rules in the sense of values (norms), concrete legal regulations and legal systems. The technical collection of legal materials in this study is a literature study (bibliography study) through the collection of legal materials as written information originating from various legal sources in the form of legislation, jurisprudence, conventions, legal science books, legal journals, and legal reviews, then the technical collection of legal materials in this study also uses documentation studies, namely by recording information from legal materials related to legal reconstruction in the regulation and supervision of nursing practices in Indonesia, normatively or ideas or ideas. The results of the study show that in essence, nurses as a profession always and always serve sincerely to fellow human beings, prioritizing the interests of nursing assistance and patient health above their own personal interests, which are in the form of bio-psychosocial-spiritual cultural humanistic services using a holistic approach, based on nursing science and skills, and using the Nursing Code of Ethics as the main requirement in implementing Nursing Care.
Muyu Raymi, the Seeds Festival: Indigenous Women’s Means to Sustain, Resist, and Rebuild
Creators: name: Toro-Mayorga, Lorena
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 451905
subject: Global Indigenous studies sciences
classificationCode: 440107
subject: Social and cultural anthropology
classificationCode: 470212
subject: Multicultural, intercultural and cross-cultural studies

description: Among the Raymis, the Indigenous celebrations of the Andes, the seeds festival Muyu Raymi has a unique path. It is a colorful one-day event that most explicitly exemplifies interculturalidad and the achievements of Indigenous Peasant politics at a local level in Ecuador. Nevertheless, Indigenous women’s active and committed involvement in the event is not sufficiently understood from the intersection of culture and politics. This work aims to identify the ways in which Indigenous women have managed to link themselves to Muyu Raymi and what Muyu Raymi shows about our understanding of interculturalidad. This work argues Muyu Raymi has its origins in the dawn of neoliberalism and remains connected to a long process of resistance led by Indigenous women. The findings are discussed through a lens of interculturalidad that highlights people’s ability to sustain, resist, and rebuild their ways of living. The analysis considers the existence of a relationship between human and non-human actants as explainer of social life; in this case, Indigenous women and the seeds. This work highlights the transformative potential of the women-seeds connections and their mixed strategies to resist and support systems of power, through a history that correctly attributes credit to women as history makers.
sj-docx-1-ine-10.1177_15910199231196329 - Supplemental material for Device use trends in neuroendovascular procedures in the United States from 2015 to 2020
Creators: name: Adapa, Arjun Rohit
name: Siddiqui, Fazeel M.
name: Pandey, Aditya S.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Neuroscience

description: Supplemental material, sj-docx-1-ine-10.1177_15910199231196329 for Device use trends in neuroendovascular procedures in the United States from 2015 to 2020 by Arjun Rohit Adapa, Fazeel M. Siddiqui and Aditya S. Pandey in Interventional Neuroradiology
sj-docx-1-chl-10.1177_17475198231189838 – Supplemental material for A thermoregulated phase-transfer ruthenium nanocatalyst for the atmospheric hydrogenation of α,β-unsaturated ketones
Creators: name: Gao, Bin
name: Wang, Yanhua
Publisher: name: SAGE Journals
Year: 2023
Subjects: Materials Engineering not elsewhere classified

description: Supplemental material, sj-docx-1-chl-10.1177_17475198231189838 for A thermoregulated phase-transfer ruthenium nanocatalyst for the atmospheric hydrogenation of α,β-unsaturated ketones by Bin Gao and Yanhua Wang in Journal of Chemical Research
Experimental and theoretical investigations for surge prevention in gas turbines
Creators: name: REGGIO, FEDERICO
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The innovative energy systems equipped with large volume size connected with a gas turbine present critical issues related to the surge risk especially during transient operations. In comparison with standard gas turbines, the volume size generates different behaviour during dynamic operations (with significant surge risk), especially considering that innovative additional components include important dynamic constraints. The main examples of power systems including the effect of an additional volume connected with a turbine are: fuel cell based hybrid plants, humid cycles, externally fired layouts and innovative systems including high temperature thermal storage devices. The aim of the work in this thesis is to cope with the surge instability in fluid dynamic machines through the analysis of vibro-acoustic signals generated from the turbine compressor. Investigations based on acoustic and vibrational measurements appear to provide an interesting diagnostic and predictive solution by adopting a suitable quantifier calculated from microphone and accelerometer signals. For this scope, a wide experimental activity was carried out with a test rig composed by a T100 microturbine connected to a modular vessel. Starting from the stable operation, the instability of surge was produced progressively by closing a valve in the main air line while the system was equipped with different dynamic probes to measure the vibrations during normal and surge operations. A machine dynamical characterization was useful for a better interpretation of signals during its transient to the surge. Hence different possible methods of incipient surge identification have been developed through the use of different signal processing techniques in time, frequency and angle domain. A Vibro-acoustic analysis was carried out to develop precursors which are able to highlight the unstable operative zone approaching and to produce control data (e.g. an on/off signal for a bleed valve) for surge prevention. Finally, four of surge precursors found were implemented into a new diagnostic real-time software. By using the measured data, this innovative tool has proved to be able to recognise a surge incipience condition by comparing the precursor values with a set of moving thresholds.
Development of novel formulations based on biopolymers
Creators: name: LI, KUN
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: Biopolymers, generally prepared from renewable sources, have attracted increasing attention due to their unique properties, such as nontoxicity, biodegradability and biocompatibility. Indeed, the above materials have been widely applied in the biomedical field, in the development of electronic devices as well as in the food packaging. Two of the most extensively studied and exploited biopolymers are poly(lactic acid) (PLA) and polycaprolactone (PCL), which have been the objects of the present work. Despite the significant interest in these polymers, for large-scale exploitation of both PLA and PCL, it is necessary to take into account some specific issues concerning their properties. In this regards, it is relevant to underline that the methods, which can be applied for improving their characteristics or those used for disclosing new features, have to take into account the economic impact and the "bio" nature of the material, which should be maintained in the final formulation. In particular, in the case of PLA, one of the major issues, which reduces its exploitation in durable applications, is its low hydrolytic stability, compared with other similar materials. Moreover, in the applications requiring high gas barrier, the use of PLA is critical and needs a further reduction of its gas permeability. Furthermore, concerning exploitations, where electrical and thermal conductivity is demanded, the insulating nature of the above biopolymers, requires the applications of proper conductive fillers. As such, the main aim of the thesis work main has been the improvement of the two biopolymer properties, developing novel formulations, whose design has taken into account all the mentioned issues.
In the case of PLA, the barrier properties, the resistance to hydrolytic degradation as well as the antistatic features have been improved by modifying the material surface by means of the application of methods based on the chemical grafting or the Layer by Layer deposition and on the use of proper fillers, such as Polyhedral Oligomeric Silsesquioxane (POSS) and graphene oxide (GO). In addition, formulations capable of imparting thermal and electrical conduction to both PLA and PCL have been studied, combining the two biopolymers with graphite nanoplatelets (GNP).
Gramsci, architettura e letteratura
Creators: name: Spinazzola, Vittorio
Publisher: name: ACME
Year: 2017

description: "Dirigente politico comunista di alto livello e uomo di cultura raffinato, Antonio Gramsci è una delle personalità più significative tra gli intellettuali del Novecento italiano. Particolarmente notevole è l’insieme degli scritti di interesse linguistico-letterario nei quaderni vergati nei lunghi anni di prigionia sotto il regime fascista e pubblicati dopo il 1945. A rileggere oggi queste note carcerarie è facile rendersi conto che il loro punto focale è d’indole non storica ma teorica: riguarda infatti il problema generalissimo dei destinatari dell’attività di scrittura".
description: ACME, V. 70, N. 1 (2017)
Developing Metal-Halide Layered Perovskite Nanomaterials for Optoelectronics
Creators: name: DHANABALAN, BALAJI
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The abundant chemical tunability along with outstanding optoelectronic properties of the 2D metal-halide layered perovskite materials, as well as the potential prospect on understanding the structure-property relationships at the molecular level, provide enormous opportunity for the scientific community on designing new and efficient 2D metal-halide layered perovskites for a specific optoelectronic application. These materials still require attention on understanding their fundamental electronic properties and on controlling their synthesis parameters to produce high quality materials. Moreover, the synergy between the organic and inorganic compounds in these systems further opens up the possibility to unlock novel optoelectronic properties by simply integrating many other available functional organic molecules into these structures. This thesis is dedicated to the synthesis of 2D lead-bromide Ruddlesden Popper layered perovskite materials through a simple synthesis technique and by using different organic molecules. It targets a full investigation of the photo-physical properties of the as synthesized materials. Moreover, it presents detailed studies on the effect of structural rigidity and electron-phonon interaction provided by organic molecules on the emission efficiencies of 2D layered perovskites, and their emission tunability by using organic molecules with different architectures. In a more technological view, this thesis summarizes the work performed on the integration of 2D layered perovskites in polymer films and their emission enhancement by mechanical stress.
NEW PHARMACOLOGICAL TARGETS FOR CYSTIC FIBROSIS TREATMENT FROM OMICS PROFILING OF F508del-CFTR EXPRESSING CELLS.
Creators: name: BRACCIA, CLARISSA
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: Cystic fibrosis (CF) is a genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding an anion channel expressed on the epithelial cells of a variety of tissues. The deletion of phenylalanine in position 508 (F508del) is the most frequent CF-causing mutation, causing impaired trafficking and activity of the mutant channel. Today, two classes of drugs are available to treat CF: potentiators (molecules that increase the mutant CFTR function on the cell surface) and correctors (molecules that improve the processing and the delivery of mutant CFTR to the cell surface). It has been demonstrated that the combination of molecules exploiting different mechanisms of action is needed to achieve a therapeutically relevant rescue of CFTR. The aim of this project is to apply mass spectrometry (MS)-based omics techniques to understand what is associated to CFTR rescue and thus finding new potential targets for CF pharmacological treatment. Several strategies were applied for the functional rescue of CFTR at the plasma membrane (both pharmacological and genetic rescue). Proteomic and lipidomic profilings of F508del-CFTR expressing cells were performed after the application of these rescue strategies. The proteomic experiments were performed following the SWATH label-free quantification workflow, after the optimization of the panhuman ion library for CF research. Together with these experiments, Localisation of Organelle Proteins by Isotope Tagging after Differential ultraCentrifugation (LOPIT-DC) workflow was also applied to detect proteins that change their subcellular localization after the treatment with the most used corrector available for CF therapy (VX-809). Several candidate targets were found to be involved in F508del-CFTR rescue. Compounds aiming at the inhibition of these putative targets were tested on both immortalized and primary cells. Further validation studies are needed to confirm these results.
A deep learning approach to the detection of illegal insider trading
Creators: name: Adusumilli, Anoop
Publisher: name: No Publisher Supplied
Year: 2025

description: Illegal Insider trading involves the exploitation of non-public information for personal gain, posing risks to market fairness and investor trust. Tackling this issue is vital for ensuring transparency and equity in financial dealings. It is estimated that illegal insider trading is present in approximately 20% of merger and acquisition events and 5% of quarterly earnings announcements [1]. Our study introduces an innovative deep learning-based approach, leveraging a combination of text classification, time series forecasting and anomaly detection. By analyzing litigation releases from regulatory bodies and incorporating market and social media data, we develop a method to detect and predict signs of illegal insider trading. The addition of explainable AI techniques in our study offers clarity and transparency in the predictive models, making the rationale behind each decision more understandable.Our approach shows the potential of deep learning methods in identifying and providing insights into the unusual trading patterns concerning illegal insider trading and is a step towards more sophisticated monitoring tools. Our results demonstrate that the proposed approach effectively identifies potential instances of illegal insider trading, showing promise in detecting subtle patterns and anomalies that may indicate suspicious activity in financial markets. The findings suggest avenues for financial regulators and institutions to enhance their surveillance mechanisms, contributing to the ongoing efforts to maintain the fairness and reliability of financial markets.
Expression, role and regulation of NK cell immune checkpoints (PD-1, KIRs, NKG2A) in Ovarian Cancer
Creators: name: GREPPI, MARCO
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: Outstanding results can be obtained with immune-checkpoints (ICs)/ligands blockade strategies (mainly PD-1/PD-L axis) in immunotherapeutic protocols for aggressive tumors. We previously showed that higher proportions of PD-1+NK cells can be detected in ovarian cancer (OC) patients. Here, we deeply characterized the features of the PD-1+NK cell subset in a large cohort of patients with high-grade serous OC subtype with the aim to dissect the NK/tumor interconnections existing in this TME. We identified two new PD-1+NK subsets occurring only in OC patients, primarily in the peritoneal fluid (PF) compartment, while absent in healthy donors. These subsets show an immature phenotype, characterized by high expression of NKG2A and NKp46, variable expression of KIRs, and low/lack expression of CD57.
Functional analyses revealed that PF-PD-1+NK cells are not anergic, but able to degranulate in response to appropriate stimuli. In addition, we found PD-1+NK cells in different tumor tissue compartments, mainly in metastatic niche, suggesting a role for PD-1 in tumor metastatic progression/promotion. However, even if PD-1+NK cells are functional and infiltrate the tumor, they are unable to produce an efficient anti-tumor response towards OC cells, due to NK cells expressing multiple ICs including PD-1,NKG2A,KIRs, and OC cells expressing both PD-Ls and HLA-I, completely impairing the NK activity. Importantly, our data show that by blocking all the ICs pathways, NK cell activity can be restored. This indicates that a proper use of multiple targeted therapies, including a combination of ICs-inhibitors, represents a possible solution to restore NK cell anti-tumor activity in seropapillary OC subtype.
Ecology and biology of the Antarctic giant fish Dissostichus mawsoni (Pisces, Nototheniidae): reproduction, trophic role and migrations in the Ross Sea region
Creators: name: DI BLASI, DAVIDE
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: Three different studies have been implemented to fill gaps in the knowledge of the Antarctic toothfish (Dissostichus mawsoni) life cycle in the Ross Sea. First, presence, abundance and size distribution of toothfish in the shelf, in areas periodically covered by sea ice, were investigated by means of Baited Remote Underwater Video systems (BRUVs), an emerging technology never employed before in such kind of habitat. The study was developed from 2015 to 2018 in McMurdo Sound and Terra Nova Bay, it highlighted the efficacy of the methodology for investigating the species, recording dozens of fish of different sizes. We started to make some inferences on how environmental variables influence the distribution of the toothfish in shelf areas, but even more important, we established a working protocol useful for future works. The second section has been focused on the Second Winter Survey conducted in September-October 2019 onboard of a New Zealand fishing vessel with the aim to investigate toothfish reproductive biology, its spawning period and the eggs development and dispersion. The results obtained, combined with those from the First Winter Survey conducted in June-July 2016, allowed to have for the first time a picture of Antarctic toothfish reproduction: the spawning occurs in a wide area in correspondence of the Pacific Antarctic Ridge, it happens in the middle of the winter, and eggs set during all their development in the surface layer of the water column. The last part of the work put light on the fate of toothfish after spawning, a question arose from the observation of the high percentage of sensibly debilitated individuals (named ?axe handle?) in the breeding ground. Samples of muscles from six individuals (two ?axe handle? and two regular from the breeding area, and two regular from the shelf) were investigated with regard to lipid distribution and composition. The analysis led us to reason on lipid mobilization and usage as energy reserve and/or for neutral buoyancy for reproductive migration, how consistent is their depletion and if toothfish actively feed in the northern area. Different hypotheses on what could cause the frequent poor condition after-spawning and its potential consequences have been illustrated, with the aim to give cues for future insights.
THE EFFECT OF AWE ON INTERPRETATIONS OF AMBIGUOUS STIMULI
Creators: name: Freites, Eva Rosa Bori
Publisher: name: ProQuest
Year: 2025
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5203
subject: Clinical and health psychology
classificationCode: 520302
subject: Clinical psychology

description: The theoretical conceptualization of awe, in addition to preliminary research, suggests
that awe may facilitate the intake and integration of new information and impact the way we use
our existing knowledge structures. The aim of this study was to explore the potential effect of an
awe induction on interpretations of ambiguous stimuli. Participants were randomly assigned to a
prompt designed to induce either awe, amusement or a neutral emotion. Following the
induction, participants completed a judgement task in which they were shown neutral faces and
asked to judge the emotional valence of the face. After, participants read a series of ambiguous
scenarios and were asked to report how pleasant they imagined the situation to be. Finally,
participants completed a free-choice recognition task in which they were shown previously seen
and unseen faces. It was hypothesized that 1) those in the awe condition would spend more time
viewing neutral faces before making interpretations; 2) those in the awe condition would make
more “unclear” judgments of the emotional valence of neutral faces; 3) those in the awe
condition would demonstrate higher discriminability in the recognition task. It was also
hypothesized that awe would attenuate more negative interpretations of ambiguous scenarios
associated with more symptoms of depression, social anxiety, and moral. However, analyses
revealed no statistically significant effects of awe on the dependent measures. Several
limitations of the study should be considered when interpreting the findings. Future research
requires greater clarity in how we think about the accommodative aspect of awe, and much more
research needs to be conducted before considering its role in cognitive interventions.
Additional file 1 of Distribution and extent of suitable habitats of Ruspoli’s Turaco (Tauraco ruspolii) and White-cheeked Turaco (Tauraco leucotis) under a changing climate in Ethiopia
Creators: name: Aligaz, Mulatu Ayenew
name: Kufa, Chala Adugna
name: Ahmed, Ahmed Seid
name: Argaw, Hailu Tilahun
name: Tamrat, Misganaw
name: Yihune, Mesele
name: Atickem, Anagaw
name: Bekele, Afework
name: Bogale, Bezawork Afework
Publisher: name: figshare
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Supplementary Material 1
GNSS contribution to monitor severe rainfalls: an innovative procedure for wide and orographically complex area with existing infrastructures
Creators: name: FERRANDO, ILARIA
Publisher: name: Universit� degli studi di Genova
Year: 2017

description: The research activity concerned the development of an innovative methodology to monitor the content of Precipitable Water Vapour (PWV), starting from Zenith Tropospheric Delay (ZTD) estimations obtained from GNSS permanent stations, and Pressure (P) and Temperature (T) observed in meteorological sensors networks. In particular, an automatized procedure, named G4M (GNSS for Meteorology), for preparing and elaborating the data collected from the existing infrastructures and for producing PWV maps will be presented. The G4M procedure has been applied to study two critical events occurred on Genoa city; this analysis led to the definition of a ?Heterogeneity Index?, accounting for PWV spatial variability, which has been considered a promising indicator to highlight and locate severe meteorological events in time and space. Additionally, ZTD and PWV time series have been obtained for selected GNSS Permanent Stations in order to identify recognizable patterns in ZTD/PWV that can be related to the occurrence of severe meteorological events.
Development of a watershed health assessment framework integrating ecological, social, cultural, economic and policy attributes
Creators: name: Talampas, Shella I.
name: Shrestha, Sangam
name: Mohanasundaram, S.
name: Loc, Ho Huu
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Watershed health assessment is vital for effective resource management, necessitating an integrated framework that captures the multidimensional nature of watershed health and guides protection and restoration efforts. This study presents the development of the Integrated Watershed Health Assessment Framework (IWHF), incorporating ecological, social, cultural, economic and policy attributes to comprehensively assess watershed health as a socio-ecological system. By integrating primary and secondary data, including literature reviews and expert opinions, the IWHF captures the multidimensional nature of watershed health and provides a practical tool for sustainable watershed management. The results, evaluated through the Analytic Hierarchy Process (AHP) within the context of Multi-Criteria Decision Making (MCDM), prioritize ecological factors (48.80%), followed by economic considerations (21.90%), socio-cultural factors (16.91%) and policy aspects (12.39%). This highlights the critical importance of preserving ecological integrity, emphasizing sustainable economic practices, inclusive community engagement and well-defined policy frameworks. The IWHF's holistic and flexible approach, comprehensive integration, and enhanced decision support capabilities set it apart from other frameworks, contributing to the understanding, management, and preservation of watershed health while guiding policy direction and optimizing the utilization of watershed resources.
Die Vernünftigkeit religiösen Glaubens im Zeitalter religiöser Vielfalt und der Dissens unter epistemisch Ebenbürtigen
Creators: name: Wiertz, Oliver J.
Publisher: name: Theologie und Philosophie
Year: 1970

description: Theologie und Philosophie, Bd. 95 Nr. 3 (2020): Theologie und Philosophie, Band 95, Heft 3
Additional file 1 of Multivariate comparison of taxonomic, chemical and operational data from 80 different full-scale anaerobic digester-related systems
Creators: name: Otto, Pascal
name: Puchol-Royo, Roser
name: Ortega-Legarreta, Asier
name: Tanner, Kristie
name: Tideman, Jeroen
name: de Vries, Sjoerd-Jan
name: Pascual, Javier
name: Porcar, Manuel
name: Latorre-Pérez, Adriel
name: Abendroth, Christian
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Supplementary file 1: Supplementary Figure 1. Differential expression of eight bacterial genera in different temperature conditions. Blue represents mesophilic condition (<45 ºC) and pink represents thermophilic condition (≥45 ºC). The statistical analysis was performed with DESeq2 in RStudio.
Additional file 1 of Challenges to the implementation of a multi-level intervention to reduce mistreatment of women during childbirth in Iran: a qualitative study using the Consolidated Framework for Implementation Research
Creators: name: Mirzania, Marjan
name: Shakibazadeh, Elham
name: Bohren, Meghan A.
name: Hantoushzadeh, Sedigheh
name: Khajavi, Abdoljavad
name: Foroushani, Abbas Rahimi
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1.
O. Uno studio del disgustoso nella prosa di Samuel Beckett
Creators: name: CANAPA, FRANCESCA
Publisher: name: Universit� degli studi di Genova
Year: 2020

description: This work examines the prose of Samuel Beckett from the perspective of the theme of disgust, and the way the author uses it to portray his views on reality.
The textual analysis of part of his novels and plays is supported by an interdisciplinary approach, with specific reference to the fields of sociology and psychology.
The analysis focuses on particular recurring themes in Beckett's ouvre, such as the body, the excrement, elderly sexuality, confusion between the birth and the evacuation.
Additive manufacturing and joints: Design and methods
Creators: name: FRASCIO, MATTIA
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The industrialization of the Additive Manufacturing (AM) processes is enabling the use of AM components as final product in several applications. These processes are particularly relevant for manufacturing components with optimized custom-tailored geometries. However, to fully exploit the potentiality of AM, the development of knowledge aimed to produce dedicated design methods is needed. Indeed, even if AM enables the manufacturing of new kinds of structures, e.g. 3D lattice structures, it introduces process-specific design input and limitations that needs design methods different to from the ones for subtractive manufacturing.
Design for AM (DfAM) is a design methodology that aims to take advantage of new buildable geometries but taking into account also AM processed materials anisotropy and 3D printing constraints.
Recent literature focused on the assembly of AM components and on the AM components joining to a main structure. The conclusion was that adhesive bonding is a promising joining process, especially considering its improved stress distribution compared to fastening, but at the time of writing a method that combines DfAM and adhesive bonding knowledge is not available.
The work presented in this thesis focused on developing knowledge on design for AM and bonded joints.
First step was evaluating testing methods for AM and producing data on materials properties.
Secondly, the early works on tailoring approaches for AM joints, published recently in scientific literature, were analyzed. Then AM dedicated designs, modifications and testing methods were proposed both for the adherends (in the thickness and on the surfaces) and the joints. Specifically, an innovative joint design concept was introduced, i.e. using the 3D printing parameters as bonded joint design factors.
Eventually, feasibility of performing joints using multi-material AM with conductive polymer to embed heating elements was assessed. The 3D printed through the thickness circuits is a cutting-edge approach to enable new solutions for joints structural monitoring and self-healing.