cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Quantum signaling game
Creators: name: Frackiewicz, Piotr
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: FOS: Computer and information sciences

description: We present a quantum approach to a signaling game; a special kind of extensive games of incomplete information. Our model is based on quantum schemes for games in strategic form where players perform unitary operators on their own qubits of some fixed initial state and the payoff function is given by a measurement on the resulting final state. We show that the quantum game induced by our scheme coincides with a signaling game as a special case and outputs nonclassical results in general. As an example, we consider a quantum extension of the signaling game in which the chance move is a three-parameter unitary operator whereas the players' actions are equivalent to classical ones. In this case, we study the game in terms of Nash equilibria and refine the pure Nash equilibria adapting to the quantum game the notion of a weak perfect Bayesian equilibrium.
Essays on Foreign Aid & Government Spending in Sub-Saharan Africa (SSA)
Creators: name: Daffeh, Abdou
Publisher: name: Universita degli studi di Salerno
Year: 2023
Subjects: subject: SECS-P/01 ECONOMIA POLITICA
subject: ODA
subject: Fiscal/Aid multipliers

description: 2021 - 2022
description: Does foreign aid work or not? This question is as old as aid itself. Since the aftermath of the Marshall Plan of 1948, the world has seen a huge surge in the amount of foreign aid given to developing countries. Although foreign aid is one of the key policy tools at the disposal of high-income countries to assist low- and middle-income countries, geared toward the alleviation of poverty. However, there is much controversy surrounding the allocation and effectiveness of foreign aid. This thesis revisits the debate on the effectiveness of foreign aid in enhancing economic growth in the recipient country, and it also estimates the size of both the aid and fiscal multipliers in Sub-Saharan Africa (SSA). Recently, the SSA has received more foreign aid than any other region worldwide, which indicates the need to understand the macroeconomic and institutional factors that influence the effectiveness of foreign aid and the size of both the aid and fiscal multipliers in this region. Chapter 1 of this thesis focuses on the impact of aid on growth in developing countries. Chapters 2 and 3 estimate the size of both aid and government spending multipliers in the SSA, using a linear and nonlinear model, respectively. .. [edited by Author]
description: Gli aiuti esteri funzionano oppure no? Questa domanda è vecchia quanto gli aiuti stessi. Fin dal dopo del Piano Marshall del 1948, il mondo ha assistito a un’enorme impennata nella quantità di aiuti esteri dato ai paesi in via di sviluppo. Sebbene gli aiuti esteri siano uno degli strumenti politici chiave al momento disposizione dei paesi ad alto reddito per assistere i paesi a basso e medio reddito, orientata alla riduzione della povertà. Tuttavia, c’è molta controversia riguardo all’allocazione e all’efficacia degli aiuti esteri. Questa tesi rivisita il dibattito sull’efficacia degli aiuti esteri nel promuovere la crescita economica nel paese ricevente e stima anche la dimensione sia degli aiuti che dei moltiplicatori fiscali nell’Africa sub-sahariana (SSA). Recentemente, la SSA ha ricevuto più aiuti esteri di qualsiasi altra regione al mondo, il che indica la necessità di comprendere i fattori macroeconomici e istituzionali che influenzano l’efficacia degli aiuti esteri e la dimensione sia degli aiuti che dei moltiplicatori fiscali in questa regione. Il capitolo 1 di questa tesi si concentra sull’impatto degli aiuti sulla crescita nei paesi in via di sviluppo. I capitoli 2 e 3 stimano l’entità dei moltiplicatori sia degli aiuti che della spesa pubblica nell’SSA, utilizzando rispettivamente un modello lineare e non lineare. .. [a cura dell'Autore]
Counterfactual Analysis by Algorithmic Complexity: A metric between possible worlds
Creators: name: Corrêa, Nicholas Kluge
name: De Oliveira, Nythamar Fernandes
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computational Complexity (cs.CC)
subject: FOS: Computer and information sciences

description: Counterfactuals have become an important area of interdisciplinary interest, especially in logic, philosophy of language, epistemology, metaphysics, psychology, decision theory, and even artificial intelligence. In this study, we propose a new form of analysis for counterfactuals: analysis by algorithmic complexity. Inspired by Lewis-Stalnaker's Nicholas Corrêa 2 Manuscrito-Rev. Int. Fil. Campinas, 2022. Possible Worlds Semantics, the proposed method allows for a new interpretation of the debate between David Lewis and Robert Stalnaker regarding the Limit and Singularity assumptions. Besides other results, we offer a new way to answer the problems raised by Goodman and Quine regarding vagueness, context-dependence, and the non-monotonicity of counterfactuals. Engaging in a dialogue with literature, this study will seek to bring new insights and tools to this debate. We hope our method of analysis can make counterfactuals more understandable in an intuitively plausible way, and a philosophically justifiable manner, aligned with the way we usually think about counterfactual propositions and our imaginative reasoning.
مدل پیشنهادی تراکم سکونت و توزیع فعالیت برای انطباق با اصول TOD (مورد مطالعه: منطقه ۱۲ شهر تهران)
Publisher: name: دانشگاه کردستان
Year: 2018

description: تعیین تراکم و اختلاط کاربری در طرح های توسعه شهری همواره از موضوعات مناقشه برانگیز بوده و دیدگاه های گوناگونی در این رابطه مطرح بوده است. با این حال این تفاوت رویکردها عمدتاً در بعد نظری باقی مانده و در رابطه با روش شناسی آن مطالعات چندانی انجام نشده است. یکی از رویکردهای نوین برنامه ریزی شهری به منظور تعیین تراکم و اختلاط کاربری، توسعه حمل ­ونقل عمومی محور (تی.او.دی) است. مقاله حاضر به دنبال پیشنهاد مدلی برای تعیین تراکم و اختلاط کاربری متناسب با این رویکرد است. توسعه حمل ونقل عمومی محور را عموماً مشتمل بر سه بعد طراحی، تراکم و تنوع (اختلاط) کاربری ها دانسته اند. در این پژوهش دو بعد تخصیص بهینه تراکم و تنوع (اختلاط) کاربری ها در قالب یک مسئله برنامه ریزی ریاضی با اهداف چندگانه مدل سازی شده است. در این مدل هدف نخست بیشینه سازی تراکم در مجاورت ایستگاه ها و هدف دوم کمینه سازی اختلاف نسبت شغل به سکونت از الگوی ایده آل (نسبت شاغلان ساکن به تعداد واحد مسکونی) در هر محدوده تی.او.دی.است. مجموعه ای از محدودیت ها از جمله محدودیت های سقف جمعیت و فعالیت قابل تخصیص به منظور عدم مغایرت اساسی با طرح های فرادست نیز به مدل افزوده شده اند. مدل غیرخطی به دست آمده با استفاده از تبدیلاتی به یک مسئله برنامه ریزی خطی با اهداف چندگانه و سپس با استفاده از روش محدودیت اپسیلون تعمیم یافته به یک مسئله برنامه ریزی خطی تک هدفه تبدیل گردیده است. در نهایت مدل پیشنهادی در نمونه موردی منطقه 12 کلانشهر تهران پیاده سازی و نتایج به دست آمده به تفصیل مورد تجزیه و تحلیل قرار گرفته است. با اجرای مدل، مجموعه ای از پاسخ های بهینه پارتویی برای مسئله استخراج گردید. این پاسخ ها نقش  گزینه های پیشِ روی مجموعه مدیریت شهری را ایفا می کنند و به تصمیم سازان و سیاست گذاران شهری امکان می دهند تا بنا بر اولویت ها، محدودیت ها و مقتضیات زمانی و مکانی هر یک از اهداف اختلاط و تراکم، گزینه بهینه را انتخاب کنند. این مدل و نتایج حاصل از آن می­تواند مبنای تهیه طرح­های توسعه شهری آینده قرار گیرد
Explanation of the $W$ mass shift at CDF II in the Georgi-Machacek Model
Creators: name: Chen, Ting-Kuo
name: Chiang, Cheng-Wei
name: Yagyu, Kei
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The CDF II experiment has recently determined the mass of the $W$ boson to be $m_W(\text{CDF II}) = 80.4335 \pm 0.0094~$GeV, which deviates from the standard model prediction at $7σ$ level. Although this new result is in tension with other experiments such as those at LHC and LEP, it is worth discussing possible implications on new physics by this anomaly. We show that this large discrepancy can be explained by non-aligned vacuum expectation values of isospin triplet scalar fields in the Georgi-Machacek model extended with custodial symmetry breaking terms in the potential. The latter is required to avoid an undesirable Nambu-Goldstone boson as well as to be consistent treatment of radiative corrections. With $m_W(\text{CDF II})$ as one of the renormalization inputs at the 1-loop level, we derive the required difference in the triplet vacuum expectation values, followed by a discussion of phenomenological consequences in the scenario.
description: 16 pages, 7 figures. [version 2] Updated to PRD version
Johann Sebastian Bach, Johann Gottfried Walther und die Musik von Giovanni Pierluigi Palestrina
Creators: name: Melamed, Daniel R.
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Anhand möglicher und erwiesener personeller Verbindungen, aufgrund von quellenkritischen Überlegungen ebenso wie mittels musikalischer Analysen wird erörtert, inwiefern die Kenntnis von Werken Palestrinas Bachs eigene Kompositionen beeinflusste. Daran anknüpfend wird besprochen, inwieweit das Vorbild von Palestrinas stile antico für mitteldeutsche Komponisten der Bach-Generation überhaupt bedeutend war. Besonders findet Johann G. Walther Erwähnung. Ausgehend von neu aufgefundenen Palestrina-Manuskripten aus Bachs Notenbibliothek, die nachweislich mit Walther in Verbindung stehen, wird die Frage aufgeworfen, inwiefern der Austausch des Weimarer mit dem Weißenfelser Hof mit seiner belegbaren Palestrina-Pflege Anstoß für die Auseinandersetzung beider Komponisten mit dem Italiener war. Erwähnte Artikel: Karl Gustav Fellerer: J. S. Bachs Bearbeitung der Missa sine nomine von Palestrina. BJ 1927, S. 123-132 Barbara Wiermann: Bach und Palestrina. Neue Quellen aus Johann Sebastian Bachs Notenbibliothek. BJ 2002, S. 9-28 Daniel R. Melamed: Bach und Palestrina - Einige praktische Probleme I. BJ 2003, S. 221-224 Barbara Wiermann: Bach und Palestrina - Einige praktische Probleme II. BJ 2003, S. 225-228
description: Bach-Jahrbuch, Bd. 98 (2012)
An alternative solution of Diatomic Molecules
Creators: name: Oztemel, Ozgur
name: Olgar, Eser
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The spectrum of r-1 and r-2 type potentials of diatomic molecules in radial Schrodinger equation are calculated by using the formalism of asymptotic iteration method. The alternative method is used to solve eigenvalues and eigenfunctions of Mie potential, Kratzer-Fues potential, Coulomb potential, and Pseudoharmonic potential by determining the $α, β, γ$ and $σ$ parameters.
Ritornell - Ritornellform - Ritornellkonstruktion - Aphorismen zu einer adäquaten Beschreibung Bachscher Werke
Creators: name: Zehnder, Jean-Claude
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Ausgangspunkt des Textes ist die Behauptung, die Bach-Forschung sei im Begriff, ihre gemeinsame Sprache zu verlieren. Anhand der Fragen „Was ist ein Ritornell?“ - „Was ist eine Episode?“ wird versucht, unterschiedliche Positionen einander anzunähern. Erwähnte Artikel: Carl Dahlhaus: Bachs konzertante Fugen. BJ 1955, S. 47-72 Siegbert Rampe: "Monatlich neüe Stücke" - Zu den musikalischen Voraussetzungen von Bachs Weimarer Konzertmeisteramt. BJ 2002, S. 61-104 Michael Maul: "Alles mit Gott und nichts ohn' ihn" - eine neu aufgefundene Aria von Johann Sebastian Bach. BJ 2005, S. 7-34 Karl Heller: Rezension zu: Matthias Geuting: Konzert und Sonate bei Johann Sebastian Bach [...]. BJ 2008, S. 343-350
description: Bach-Jahrbuch, Bd. 98 (2012)
Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies
Creators: name: Gao, Hongmei
name: Bhattacharya, Tanmoy
name: Cohen, Myron S.
name: Haynes, Barton F.
name: Daniels, Marcus G.
name: Greene, Kelli
name: Tang, Haili
name: Sethi, Anurag
name: Korber, Bette
name: Gao, Feng
name: Li, Ming
name: Shaw, George M.
name: Kumar, Amit
name: Seaman, Michael S.
name: Lapedes, Alan S.
name: Montefiori, David C.
name: Gnanakaran, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: A steady increase in knowledge of the molecular and antigenic structure of the gp120 and gp41 HIV-1 envelope glycoproteins (Env) is yielding important new insights for vaccine design, but it has been difficult to translate this information to an immunogen that elicits broadly neutralizing antibodies. To help bridge this gap, we used phylogenetically corrected statistical methods to identify amino acid signature patterns in Envs derived from people who have made potently neutralizing antibodies, with the hypothesis that these Envs may share common features that would be useful for incorporation in a vaccine immunogen. Before attempting this, essentially as a control, we explored the utility of our computational methods for defining signatures of complex neutralization phenotypes by analyzing Env sequences from 251 clonal viruses that were differentially sensitive to neutralization by the well-characterized gp120-specific monoclonal antibody, b12. We identified ten b12-neutralization signatures, including seven either in the b12-binding surface of gp120 or in the V2 region of gp120 that have been previously shown to impact b12 sensitivity. A simple algorithm based on the b12 signature pattern was predictive of b12 sensitivity/resistance in an additional blinded panel of 57 viruses. Upon obtaining these reassuring outcomes, we went on to apply these same computational methods to define signature patterns in Env from HIV-1 infected individuals who had potent, broadly neutralizing responses. We analyzed a checkerboard-style neutralization dataset with sera from 69 HIV-1-infected individuals tested against a panel of 25 different Envs. Distinct clusters of sera with high and low neutralization potencies were identified. Six signature positions in Env sequences obtained from the 69 samples were found to be strongly associated with either the high or low potency responses. Five sites were in the CD4-induced coreceptor binding site of gp120, suggesting an important role for this region in the elicitation of broadly neutralizing antibody responses against HIV-1.
Supporting undergraduate management students to develop employability skills
Creators: name: Rajendran, Diana
name: Weaver, Debbi
name: Bell, Amanda S
name: Jopp, Ryan
Publisher: name: La Trobe
Year: 2023

description: A second-year undergraduate self-directed learning project has previously been ranked relatively low by students, and was recognised as requiring additional support strategies to assist students to develop teamwork and independent learning skills. This paper reports on interventions made to the teaching strategies, and the results of an evaluation project aimed at determining the effectiveness of the new support mechanisms. Key findings were the outcome of re-introducing the input of teaching staff to inform and respond to student querries in the classroom, as one method of improving feedback to students and increasing motivation, and of introducing structured activities on groupwork early in semester, to assist students in forming teams, negotiating roles and improving self awareness and taking responsibility for their learning by reflection. This paper also investigates the applicability of the new learning model in developing and demonstrating employability skills of students in a classroom environment.

['Australian and New Zealand Academy of Management. [21sh : 2007 : Sydney, Australial]']
Strong coupling of quantum emitters and the exciton polariton in MoS$_2$ nanodisks
Creators: name: Ji, Feng-Zhou
name: Bai, Si-Yuan
name: An, Jun-Hong
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: As a quasiparticle formed by light and excitons in semiconductors, the exciton-polariton (EP) as a quantum bus is promising for the development of quantum interconnect devices at room temperature. However, the significant damping of EPs in the material generally causes a loss of quantum information. We propose a mechanism to overcome the destructive effect of a damping EP on its mediated correlation dynamics of quantum emitters (QEs). Via an investigation of the near-field coupling between two QEs and the EP in a monolayer MoS$_{2}$ nanodisk, we find that, with the complete dissipation of the QEs efficiently avoided, a persistent quantum correlation between the QEs can be generated and stabilized even to their steady state. This is due to the fact that, with upon decreasing the QE-MoS$_2$ distance, the QEs become so hybridized with the EP that one or two bound states are formed between them. Our result supplies a useful way to avoid the destructive impact of EP damping, and it refreshes our understanding of the light-matter interaction in absorbing medium.
Probing the interstellar medium of NGC1569 with Herschel
Creators: name: Lianou, Sophia
name: Barmby, Pauline
name: Remy-Ruyer, Aurelie
name: Madden, Suzanne C.
name: Galliano, Frederic
name: Lebouteiller, Vianney
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: NGC1569 has some of the most vigorous star formation among nearby galaxies. It hosts two super star clusters (SSCs) and has a higher star formation rate (SFR) per unit area than other starburst dwarf galaxies. Extended emission beyond the galaxy's optical body is observed in warm and hot ionised and atomic hydrogen gas; a cavity surrounds the SSCs. We aim to understand the impact of the massive star formation on the surrounding interstellar medium in NGC1569 through a study of its stellar and dust properties. We use Herschel and ancillary multiwavelength observations, from the ultraviolet to the submillimeter regime, to construct its spectral energy distribution, which we model with magphys on ~300pc scales at the SPIRE250 μm resolution. The multiwavelength morphology shows low levels of dust emission in the cavity, and a concentration of several dust knots in its periphery. The extended emission seen in the ionised and neutral hydrogen observations is also present in the far-infrared emission. The dust mass is higher in the periphery of the cavity, driven by ongoing star formation and dust emission knots. The SFR is highest in the central region, while the specific SFR is more sensitive to the ongoing star formation. The region encompassing the cavity and SSCs contains only 12 per cent of the dust mass of the central starburst, in accord with other tracers of the interstellar medium. The gas-to-dust mass ratio is lower in the cavity and fluctuates to higher values in its periphery.
description: MNRAS accepted; 22 pages, 13 figures, 5 tables
WALLABY Pilot Survey: Public release of HI kinematic models for more than 100 galaxies from phase 1 of ASKAP pilot observations
Creators: name: Deg, N.
name: Spekkens, K.
name: Westmeier, T.
name: Reynolds, T. N.
name: Venkataraman, P.
name: Goliath, S.
name: Shen, A. X.
name: Halloran, R.
name: Bosma, A.
name: Catinella, B.
name: de Blok, W. J. G.
name: Dénes, H.
name: Di Teodoro, E. M.
name: Elagali, A.
name: For, B. -Q.
name: Howlett, C.
name: Józsa, G. I. G.
name: Kamphuis, P.
name: Kleiner, D.
name: Koribalski, B.
name: Lee-Waddell, K.
name: Lelli, F.
name: Lin, X.
name: Murugeshan, C.
name: Oh, S.
name: Rhee, J.
name: Scott, T. C.
name: Staveley-Smith, L.
name: van der Hulst, J. M.
name: Verdes-Montenegro, L.
name: Wang, J.
name: Wong, O. I.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the Widefield ASKAP L-band Legacy All-sky Blind surveY (WALLABY) Pilot Phase I HI kinematic models. This first data release consists of HI observations of three fields in the direction of the Hydra and Norma clusters, and the NGC 4636 galaxy group. In this paper, we describe how we generate and publicly release flat-disk tilted-ring kinematic models for 109/592 unique HI detections in these fields. The modelling method adopted here - which we call the WALLABY Kinematic Analysis Proto-Pipeline (WKAPP) and for which the corresponding scripts are also publicly available - consists of combining results from the homogeneous application of the FAT and 3DBAROLO algorithms to the subset of 209 detections with sufficient resolution and S/N in order to generate optimized model parameters and uncertainties. The 109 models presented here tend to be gas rich detections resolved by at least 3-4 synthesized beams across their major axes, but there is no obvious environmental bias in the modelling. The data release described here is the first step towards the derivation of similar products for thousands of spatially-resolved WALLABY detections via a dedicated kinematic pipeline. Such a large publicly available and homogeneously analyzed dataset will be a powerful legacy product that that will enable a wide range of scientific studies.
description: Accepted to PASA
Measurement of g-factors of ground and excited optical states of Er3+ in YLiF4 and LuLiF4 in zero dc magnetic field by photon echo method
Creators: name: Lisin, V. N.
name: Shegeda, A. M.
name: Samartsev, V. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences
subject: cond-mat.mtrl-sci

description: New scheme of definition of g-factors as ground as excited optical states of a paramagnetic ion in zero external constant magnetic field has been proposed and experimentally realized in optical systems in which Zeeman Effect is manifested. A pulse of a weak magnetic field leads to occurrence of relative phase shifts of the excited dipoles and, as consequence, to modulation of a photon echo waveform if magnetic pulse (MP) overlaps in time with echo-pulse. The modulation periods of the waveform depend on polarization of the laser light, which excites the photon echo. The values of these periods for σ- and π- laser light polarization have been measured and then the g-factors of the ground 4I15/2 and excited 4F9/2 states of the Er3+ ion in the LuLiF4 and the YLiF4 matrices have been determined. Values of the g-factors have been compared with the known literary data.
description: 9 pages, 4 figures, 1 table
ارزیابی تطبیقی گذرگاه های همسطح و پل های عابر پیاده در قابلیت پیاده مداری خیابان های شهری (نمونه موردی: خیابان کریمخان زند شهر تهران)
Publisher: name: دانشگاه کردستان
Year: 2018

description: وقوع انقلاب صنعتی، رشد شهرنشینی و افزایش جمعیت بر مساحت شهرها تأثیر شگرفی گذاشته و سبب افزایش سرسام آور\nتعداد اتومبیل ها و خیابان هایی شده که با هدف تسهیل حرکت سواره به وجود آمدند. یکی از مهمترین مشکلات مطرح در\nخیابان های شهری، تداخل عابر پیاده و سواره در گذر عرضی است که دغدغه ای اساسی برای شهروندان به شمار میرود\nبرای حل این معضل، احداث پل های هوایی در ایران مورد حمایت ارگانهای مربوطه قرار گرفته و قابلیتی به منظور افزایش\nپیاده مداری خیابان های شهری تصور شده است. این پژوهش کاربردی درصدد ارزیابی تطبیقی پل های هوایی با عبور\nهم سطح از خیابان های شهری طبق دیدگاه پیاده مداری است. پژوهش حاضر از نوع توصیفی_تحلیلی است و از روش\nتحلیل شبکه ای ( ای.ان.پی)برای ارزیابی یافته ها بهره گرفته شده است. بدین ترتیب پس از مطالعه مبانی نظری پژوهش به\nروش اسنادی_کتابخانه ای، معیارهای مناسب سنجش قابلیت پیاده مداری به روش دلفی وزن دهی شده و جمع آوری\nاطلاعات میدانی به روش پیمایشی با تکمیل پرسشنامه از شهروندان در محدوده مورد مطالعه انجام گرفته است. اطلاعات\nکسب شده برای ارزیابی در نرم افزار سوپر دسیشنز وارد گردید و سه امکان انتخاب برای شهروندان، شامل گذر از پل\nهوایی عادی، گذر به وسیله پل هوایی مکانیزه و عبور هم سطح از خیابان برای ارزیابی پل های عابر در قابلیت پیاده مداری\nخیابان کریم خان زند شهر تهران در نظر گرفته شد. یافته ها نشان می دهد که براساس نقطه نظرات بهره برداران به ترتیب\nمعیارهای امنیت و ایمنی، جابه جایی و دسترسی و شرایط فیزیکی، درجه اهمیت بالاتری نسبت به سایر معیارها در انتخاب\nپل های عابر پیاده برای گذر از عرض خیابان دارند. همچنین برخلاف تصور مدیران شهری، عبور عرضی هم سطح با کسب\nامتیاز ( ای=0.36)از مطلوبیت بیشتری نسبت به پل های هوایی و پل مکانیزه (بی=0.33)ز مزیت بیشتری به نسبت پل\nمعمولی ( سی=0.30)در قابلیت پیاده مداری خیابان برخوردار است که از این رو تجدید نظری جدی در روند کنونی توسعه\nپل های عابر پیاده در کشور را ضروری می نماید
Chorliste und Chorgröße bei Johann Sebastian Bach. Neue Überlegungen zu einem alten Thema
Creators: name: Rifkin, Joshua
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Der Text tritt einigen nach Meinung des Autors fehlerhaften Interpretationen von Originaldokumenten zur Bach‘schen Aufführungspraxis, besonders zu Umfang und Besetzung seiner Chöre, entgegen. Im Folgenden wird detailliert auf eine Auswahl solcher Dokumente (Schul- und Gottesdienstordnungen, Choraufstellungen) und jeweiligen Interpretationen eingegangen, die auf ihre Aussagekraft geprüft werden. Ergebnis der Auswertung ist die Behauptung, Thesen zur Chorgröße in Bachs Aufführungen, die einseitig auf Grundlage dieser Texte gestellt würden, seien bar jeder tragfähigen Begründung. Erwähnte Artikel: Bernhard Friedrich Richter: Stadtpfeifer und Alumnen der Thomasschule in Leipzig zu Bachs Zeit. BJ 1907, S. 32-78 Hans-Joachim Schulze: Studenten als Bachs Helfer bei der Leipziger Kirchenmusik. BJ 1984, S. 45-72 Christine Fröde: Zu einer Kritik des Thomanerchores von 1749. BJ 1984, S. 53-58 Andreas Glöckner: "... daß ohne Hülffe derer Herren Studiosorum der Herr Cantor keine vollstimmende Music würde bestellen können ...". Bemerkungen zur Leipziger Kirchenmusik vor 1723 und nach 1750. BJ 2001, S. 131-140 Hans-Joachim-Schulze: Rezension zu: Andrew Parrott: Bachs Chor [...]. BJ 2003, S. 267-270 Andreas Glöckner: Alumnen und Externe in den Kantoreien der Thomasschule zur Zeit Bachs. BJ 2006, S. 9-36 Martin Petzoldt: Zum Verhältnis Friedrich Nietzsches zu Johann Sebastian Bach - Nietzsches Urgroßvater, Alumnus der Thomasschule und Präfekt unter Bach. BJ 2007, S. 229-242
description: Bach-Jahrbuch, Bd. 98 (2012)
بررسی روش ترکیبی در تشخیص جزایر گرمایی و راهکار تعدیل از طریق ظرفیت فضای سبز شهری (مورد مطالعه: شهر اصفهان)
Publisher: name: دانشگاه کردستان
Year: 2018

description: پدیده جزایر گرمایی شهری یکی از چالش هایی است که در پی گسترش بدون برنامه شهرها گریبانگیر اغلب کلان شهرها شده\nاست. از آنجایی که در هر شهر و یا منطقه شهری پدیده جزیره گرمایی برآیند عوامل متفاوتی است که می تواند منحصر به\nآن مکان باشد، راهکارهای ارائه شده برای آن منطقه نیز باید در جهت تصحیح و یا تقلیل آن عوامل باشد. در این پژوهش\nسعی شده به کمک داده هـای ماهواره ای شامل یک تصویر حرارتی روزانه  18جولای  2015ماهواره لندست و همچنین\nتصویر شبانه ماهواره مدیس و سیستم اطلاعات جغرافیایی به همراه داده زمینی نزدیکترین ایستگاه هواشناسی شهری\nبه محل شبیه سازی جزایر گرمایی شهر اصفهان مورد بررسی قرار گیرد. در این راستا میزان تأثیرپذیری کاربری های مختلف\nبر ایجاد و شدت جزایر گرمایی در اصفهان بررسی شده و بر پایه یافته های تحقیق، پیشنهادهای قابل اجرا در حوزه فعالیت\nشهری با نگاه ویژه بر روی فضای سبز داده شده است. از میان کاربری های شهری به کمک شبیه سازی تأثیر فضاهای\nسبز و به ویژه فضای سبز حاشیه معابر بر خرد اقلیم های شهری در یکی از محدوده های دارای با قدمتترین فضای سبز\nحجمی شهر، محدوده عباس آباد مورد مطالعه قرارگرفت. در این راستا این فضای سبز شهری با درختان با قدمت زیاد در\nبافت تاریخی اصفهان انتخاب شد و به وسیله نرم افزار انوی-مت مدل سازی شد. نتایج این شبیه سازی برای تابستان\n 2015میلادی نشان میدهد که در سه نقطه انتخاب شده باوجود نزدیکی فواصل، حدود 1درجه تفاوت دمایی مشاهده\nمی شود که نزدیکی به بدنه های آبی و به خصوص فضای سبز از عوامل اصلی تأثیرگذار می باشند و همچنین داده های\nزمینی انطباق نسبی با روند تغییرات در نقاط دارند. بر این اساس سناریوهای مختلفی از حضور فضای سبز پیشنهاد و به\nکمک شبیه سازی مورد ارزیابی قرار گرفت. نتایج این مقاله نشان میدهد که فضاهای سبز خرد می تواند در صورت طراحی\nمناسب و بر مبنای اصول علمی تأثیر مناسبی در تعدیل اثرات حرارتی جزایر گرمایی در مقیاس های کوچک داشته باشد\nهمچنین به علت گستردگی محدوده شهری روش های ترکیبی پیشنهادی در این پژوهش میتواند تحلیل های حداکثری\nبرای اقدامات کاربردی به منظور کاهش اثرات منفی جزایر گرمایی برای مدیریت شهری به ارمغان آورد
Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences
Creators: name: Lakhani, Vinal V.
name: Ding, Feng
name: Dokholyan, Nikolay V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Polyglutamine (polyQ) expansion in exon1 (XN1) of the huntingtin protein is linked to Huntington's disease. When the number of glutamines exceeds a threshold of approximately 36–40 repeats, XN1 can readily form amyloid aggregates similar to those associated with disease. Many experiments suggest that misfolding of monomeric XN1 plays an important role in the length-dependent aggregation. Elucidating the misfolding of a XN1 monomer can help determine the molecular mechanism of XN1 aggregation and potentially help develop strategies to inhibit XN1 aggregation. The flanking sequences surrounding the polyQ region can play a critical role in determining the structural rearrangement and aggregation mechanism of XN1. Few experiments have studied XN1 in its entirety, with all flanking regions. To obtain structural insights into the misfolding of XN1 toward amyloid aggregation, we perform molecular dynamics simulations on monomeric XN1 with full flanking regions, a variant missing the polyproline regions, which are hypothesized to prevent aggregation, and an isolated polyQ peptide (Qn). For each of these three constructs, we study glutamine repeat lengths of 23, 36, 40 and 47. We find that polyQ peptides have a positive correlation between their probability to form a β-rich misfolded state and their expansion length. We also find that the flanking regions of XN1 affect its probability to^x_page_count=28 form a β-rich state compared to the isolated polyQ. Particularly, the polyproline regions form polyproline type II helices and decrease the probability of the polyQ region to form a β-rich state. Additionally, by lengthening polyQ, the first N-terminal 17 residues are more likely to adopt a β-sheet conformation rather than an α-helix conformation. Therefore, our molecular dynamics study provides a structural insight of XN1 misfolding and elucidates the possible role of the flanking sequences in XN1 aggregation.
رویکردی عملیاتی در ارزیابی جریان های اصلی شکل پایدار شهر با تمرکز بر مدل شکل شهر بوم-کارا. مورد پژوهی ریخت-گونه های شهر اصفهان
Publisher: name: دانشگاه کردستان
Year: 2018

description: شکل شهر به عنوان واسط میان انسان و محیط، مظهر و تجسم جریان­های شکل دهنده و دگرگون کننده فرم مصنوع است. جریان­ های انرژی در تولید، استفاده و نگهداشت فرم شهر منجر به شکل ­گیری و دگردیسی شکل شهر می ­شود. فرم مصنوع حاصل از فرآیندها و جریان­ های یاد شده، فرستنده جریان ­های اطلاعاتی بصری و ادراکی به انسان به عنوان دریافت کننده است. در تحقیق حاضر تبادلات و تعاملات میان انسان و محیط زیست او براساس جریان ­های انرژی مورد نیاز دامنه آسایش محیطی (تمرکز بر انرژی مورد تقاضا برای گرمایش و سرمایش داخلی فرم مصنوع) و نیز جریان­های اطلاعات (بصری) در نظر گرفته می­شود. این دو جریان انرژی و اطلاعات(بصری) به عنوان جریان ­های اصلی و غالب فرم مصنوع در نظر گرفته می­شوند. در تحقیق تمامی روابط و برهم کنش ­های یکپارچه جریان­ های انرژی و اطلاعات در محتوای شکل شهر براساس مدل نظری "شکل شهر بوم _کارا" مورد تحلیل و بررسی قرار می­گیرد. پژوهش حاضر با هدف جست­وجوی روابط یکپارچه درونی میان جریان­ های اصلی شکل شهر، دو حالت شاخص بسته شدگی را مورد دقت و ریزبینی قرار می­دهد. حالت نخست شاخص بسته ­شدگی مبین نقش عناصر عمودی شکل شهر (ساختار سه بعدی محیط  هندسی فرم مصنوع) و پخشایش آنها در عملکردهای محیطی فرم مصنوع است (لوک آدولف) و حالت دوم مبین نقش عناصر افقی شکل شهر (ساختار دو بعدی محیط هندسی سطوح فرم مصنوع) و پیکره­بندی هندسی آن در پایداری جریان­های اطلاعاتی بصری است (بندیکت). بر این اساس محتوای ارزیابانه این تحقیق شامل ریخت_گونه ­های نظام ریخت ­شناسی شهر اصفهان است. نتایج تحقیق نشان می­دهد که میان دو حالت شاخص بسته­ شدگی رابطه معکوس و قوی و از لحاظ آماری معنی­دار وجود دارد که تشریح کننده این نکته است که بافت ­های قدیمی با ساختار ارگانیک دارای پایداری بالاتر محیطی (در فصول سرد سال با توجه به سرمای شدید فصول سرد سال در اقلیم گرم و خشک اصفهان ) و همچنین پایداری بالاتر جریان­ های اطلاعاتی (بصری) است.  بنابراین یکپارچگی جریان­ های بصری (اطلاعات و انرژی) براساس مدل نظری تحقیق در بافت­ های قدیمی با ساختار ارگانیک قابل اثبات است
Temperino21 [poster]
Temperino21 [poster]
Temperino21 [poster]
Creators: name: Tocchini, Alice
Publisher: name: A. Tocchini, "Temperino21", in Book of Abstract AIPH 2022, Quarta Conferenza Nazionale di Public History, Storia bene comune, Università Ca’ Foscari Venezia, M9 – Museo del ’900. Venezia-Mestre, 27-31 maggio 2022.
Year: 2022

description: Una pagina Instagram per divulgare la storia della destra e del fascismo.
Unambiguous separation of the inverse spin Hall and anomalous Nernst Effects within a ferromagnetic metal using the spin Seebeck effect
Creators: name: Wu, Stephen M.
name: Hoffman, Jason
name: Pearson, John E.
name: Bhattacharya, Anand
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The longitudinal spin Seebeck effect is measured on the ferromagnetic insulator Fe$_3$O$_4$ with the ferromagnetic metal Co$_{0.2}$Fe$_{0.6}$B$_{0.2}$ (CoFeB) as the spin detector. By using a non-magnetic spacer material between the two materials (Ti), it is possible to decouple the two ferromagnetic materials and directly observe pure spin flow from Fe$_3$O$_4$ into CoFeB. It is shown, that in a single ferromagnetic metal the inverse spin Hall effect (ISHE) and anomalous Nernst effect (ANE) can occur simultaneously with opposite polarity. Using this and the large difference in the coercive fields between the two magnets, it is possible to unambiguously separate the contributions of the spin Seebeck effect from the ANE and observe the degree to which each effect contributes to the total response. These experiments show conclusively that the ISHE and ANE in CoFeB are separate phenomena with different origins and can coexist in the same material with opposite response to a thermal gradient.
Universality in the morphology and mechanics of coarsening amyloid fibril networks
Creators: name: Rizzi, Leandro G.
name: Head, David A.
name: Auer, Stefan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biomolecules (q-bio.BM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Above a critical concentration a wide variety of peptides and proteins self-assemble into amyloid fibrils which entangle to form percolating networks called hydrogels. Such hydrogels have important applications as biomaterials and in nanotechnology, but their applicability often depends on their mechanical properties for which we currently have no predictive capability. Here we use a peptide model to simulate the formation of amyloid fibril networks, and couple these to elastic network theory to determine their mechanical properties. The simulations reveal that the time-dependence of morphological quantities characterizing the network length scales can be collapsed onto master curves by using a time scaling function that depends on the interaction parameter between the peptides. The same scaling function is used to unveil a universal, non-monotonic dependence of the shear modulus with time. The obtained insight into the structure-function relationship between the peptide building blocks, network morphology and network mechanical properties can aid experimentalists to design amyloid fibril networks with tailored mechanical properties.
description: Article (6 pages, 4 figures) + Supplementary Information (6 pages, 6 figures)
Supporting scholarly e-teaching: lessons learned from a faculty-based initiative
Creators: name: Benson, Robyn
name: Brack, Charlotte
name: Weaver, Debbi
Publisher: name: La Trobe
Year: 2023

description: Australian universities are challenged to provide training programs in the use of learning management systems (LMS) that assist staff both understand the software environment and use it effectively in their teaching practice. In this paper, we describe the development of an integrated professional development program designed for staff who want to use WebCT in their teaching. The program was part of a strategic initiative to provide centralised Information and Communication Technology infrastructure for teaching at Monash University. The integrated training program comprised a variety of strategies including: a series of 5 3-hour workshops, developed to introduce academic staff to design techniques and principles of delivery of educational material using WebCT; the option of specialist group access to workshops more tailored to meet their needs; support of networks of staff throughout the university and the use of third party instructional online tutorials. Workshops included discussion of teaching and learning issues of online course delivery, as well as hands-on use of the software. Printed resource materials to complement workshops are currently being developed. This paper discusses some of the implications of both the design and implementation of the integrated training program.

['Higher Education Research and Development Society of Australasia. [30th : 2007 : Adelaide, Australia]']
Observations on Chresiona invalida (Simon, 1898)  (Araneae: Macrobunidae) from South Africa
Creators: name: Dippenaar-Schoeman, A.S.
name: Webb, P.
Publisher: name: Zenodo
Year: 2024
Subjects: biodiversity

description: Little is known about the genus Chresiona Simon, 1903, represented by three South African species, but known only from females. Chresiona invalida (Simon, 1898) are free-running ground dwellers that make retreats under rocks and stones. The general morphology of live specimens is discussed, along with notes on their behaviour, distribution, and conservation status.
Figuralaufführungen in der Leipziger Johanniskirche zur Zeit Johann Sebastian Bachs
Creators: name: Glöckner, Andreas
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Der Text schildert eingehend kirchliche und liturgische Verhältnisse der Leipziger Johanniskirche im 18. Jahrhundert und belegt anhand detailliert dargestellter Vergütungsbelege die Mitwirkung der Thomaner an der dortigen Figuralmusik. Daran knüpfen Überlegungen zur Arbeitsweise Bachs wie zur Aufführungspraxis seiner Werke an. Erwähnter Artikel: Andreas Glöckner: Johann Sebastian Bach und die Universität Leipzig - Neue Quellen (Teil I). BJ 2008, S. 159-201
description: Bach-Jahrbuch, Bd. 98 (2012)
A Whole-Body Model for Glycogen Regulation Reveals a Critical Role for Substrate Cycling in Maintaining Blood Glucose Homeostasis
Creators: name: Todd Gehris, Abby
name: Morgan, Kevin T.
name: Elston, Timothy C.
name: Gomez, Shawn M.
name: Xu, Ke
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Timely, and sometimes rapid, metabolic adaptation to changes in food supply is critical for survival as an organism moves from the fasted to the fed state, and vice versa. These transitions necessitate major metabolic changes to maintain energy homeostasis as the source of blood glucose moves away from ingested carbohydrates, through hepatic glycogen stores, towards gluconeogenesis. The integration of hepatic glycogen regulation with extra-hepatic energetics is a key aspect of these adaptive mechanisms. Here we use computational modeling to explore hepatic glycogen regulation under fed and fasting conditions in the context of a whole-body model. The model was validated against previous experimental results concerning glycogen phosphorylase a (active) and glycogen synthase a dynamics. The model qualitatively reproduced physiological changes that occur during transition from the fed to the fasted state. Analysis of the model reveals a critical role for the inhibition of glycogen synthase phosphatase by glycogen phosphorylase a. This negative regulation leads to high levels of glycogen synthase activity during fasting conditions, which in turn increases substrate (futile) cycling, priming the system for a rapid response once an external source of glucose is restored. This work demonstrates that a mechanistic understanding of the design principles used by metabolic control circuits to maintain homeostasis can benefit from the incorporation of mathematical descriptions of these networks into “whole-body” contextual models that mimic in vivo conditions.
Stochastic modelling of cosmic ray sources for diffuse high-energy gamma-rays and neutrinos
Creators: name: Stall, Anton
name: Kaiser, Leonard
name: Mertsch, Philipp
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Cosmic rays of energies up to a few PeV are believed to be of galactic origin, yet individual sources have still not been firmly identified. Due to inelastic collisions with the interstellar gas, cosmic-ray nuclei produce a diffuse flux of high-energy gamma-rays and neutrinos. Fermi-LAT has provided maps of galactic gamma-rays at GeV energies which can be produced by both hadronic and leptonic processes. Neutrinos, on the other hand, are exclusively produced by the sought-after hadronic processes, yet they can be detected above backgrounds only at hundreds of TeV. Oftentimes, diffuse emission maps are extrapolated from GeV to PeV energies, but the sources contributing at either energies likely differ. We have modelled the production of diffuse emission from GeV through PeV energies in a Monte Carlo approach, taking into consideration the discrete nature of sources. We can generate realisations of the diffuse sky in a matter of seconds, thus allowing for characterising correlations in direction and energy. At hundreds of TeV, relevant for observations with LHAASO, Tibet AS-gamma, IceCube and the upcoming SWGO, variations between different realisations are sizeable. Specifically, we show that extrapolations of diffuse emission from GeV to PeV energies must fail and apply our results on the recent experimental findings.
description: 8 pages, 4 figures, Presented at the 38th International Cosmic Ray Conference (ICRC2023)
50 M31 black hole candidates identified by Chandra and XMM-Newton
Creators: name: Barnard, R.
name: Garcia, M. R.
name: Primini, F.
name: Murray, S. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Over the last ~5 years we have identified ~35 black hole candidates (BHCs) in M31 from their X-ray spectra. Our BHCs exhibited 0.3--10 keV spectra consistent with the X-ray binary (XB) hard state, at luminosities that are above the upper limit for neutron star (NS) XBs. When our BHC spectra were modeled with a disk blackbody + blackbody model, for comparison with bright NS XBs, we found that the BHCs inhabited a different parameter space to the NS XBs. However, BH XBs may also exhibit a thermally dominated (TD) state that has never been seen in NS XBs; this TD state is most often observed in X-ray transients. We examined the ~50 X-ray transients in our Chandra survey of M31, and found 13 with spectra suitable for analysis. We also examined 2 BHCs outside the field of view of our survey, in the globular clusters B045 and B375. We have 42 strong BHCs, and 8 plausible BHCs that may benefit from further observation. Of our 15 BHCs in globular clusters, 12 differ from NS spectra by >5 sigma. Due to improvements in our analysis, we have upgraded 10 previously identified plausible BHCs to strong BHCs. The mean maximum duty cycle of the 33 X-ray transients within 6' of M31* was 0.13; we estimate that >40% of the XBs in this region contain BH accretors. Remarkably, we estimate that BHCs contribute >90% of those XBs >1 E+38 erg/s.
description: Accepted for publication in ApJ; 8 pages, 1 figure
Control-Theoretic Modeling of Multi-Species Water Quality Dynamics in Drinking Water Networks: Survey, Methods, and Test Cases
Creators: name: Elsherif, Salma M.
name: Wang, Shen
name: Taha, Ahmad F.
name: Sela, Lina
name: Giacomoni, Marcio H.
name: Abokifa, Ahmed
Publisher: name: arXiv
Year: 2022
Subjects: subject: Systems and Control (eess.SY)
subject: Optimization and Control (math.OC)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Mathematics

description: Chlorine is a widely used disinfectant and proxy for water quality (WQ) monitoring in water distribution networks (WDN). Chlorine-based WQ regulation and control aims to maintain pathogen-free water. Chlorine residual evolution within WDN is commonly modeled using the typical single-species decay and reaction dynamics that account for network-wide, spatiotemporal chlorine concentrations only. Prior studies have proposed more advanced and accurate descriptions via multi-species dynamics. This paper presents a host of novel state-space, control-theoretic representations of multi-species water quality dynamics. These representations describe decay, reaction, and transport of chlorine and a fictitious reactive substance to reflect realistic complex scenarios in WDN. Such dynamics are simulated over space- and time-discretized grids of the transport partial differential equation and the nonlinear reaction ordinary differential equation. To that end, this paper (i) provides a full description on how to formulate a high fidelity model-driven state-space representation of the multi-species water quality dynamics and (ii) investigates the applicability and performance of different Eulerian-based schemes (Lax-Wendroff, backward Euler, and Crank- Nicolson) and Lagrangian-based schemes (method of characteristics) in contrast with EPANET and its EPANET-MSX extension. Numerical case studies reveal that the Lax-Wendroff scheme and method of characteristics outperform other schemes with reliable results under reasonable assumptions and limitations.
Discovering Transcription Factor Binding Sites in Highly Repetitive Regions of Genomes with Multi-Read Analysis of ChIP-Seq Data
Creators: name: Chung, Dongjun
name: Kuan, Pei Fen
name: Dewey, Colin
name: Sanalkumar, Rajendran
name: Bresnick, Emery H.
name: Li, Bo
name: Keleş, Sündüz
name: Liang, Kun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is rapidly replacing chromatin immunoprecipitation combined with genome-wide tiling array analysis (ChIP-chip) as the preferred approach for mapping transcription-factor binding sites and chromatin modifications. The state of the art for analyzing ChIP-seq data relies on using only reads that map uniquely to a relevant reference genome (uni-reads). This can lead to the omission of up to 30% of alignable reads. We describe a general approach for utilizing reads that map to multiple locations on the reference genome (multi-reads). Our approach is based on allocating multi-reads as fractional counts using a weighted alignment scheme. Using human STAT1 and mouse GATA1 ChIP-seq datasets, we illustrate that incorporation of multi-reads significantly increases sequencing depths, leads to detection of novel peaks that are not otherwise identifiable with uni-reads, and improves detection of peaks in mappable regions. We investigate various genome-wide characteristics of peaks detected only by utilization of multi-reads via computational experiments. Overall, peaks from multi-read analysis have similar characteristics to peaks that are identified by uni-reads except that the majority of them reside in segmental duplications. We further validate a number of GATA1 multi-read only peaks by independent quantitative real-time ChIP analysis and identify novel target genes of GATA1. These computational and experimental results establish that multi-reads can be of critical importance for studying transcription factor binding in highly repetitive regions of genomes with ChIP-seq experiments.