cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test
Creators: name: Weisemann, Jasmin
name: Krez, Nadja
name: Fiebig, Uwe
name: Worbs, Sylvia
name: Skiba, Martin
name: Endermann, Tanja
name: Dorner, Martin
name: Bergström, Tomas
name: Muñoz, Amalia
name: Zegers, Ingrid
name: Müller, Christian
name: Jenkinson, Stephen P.
name: Avondet, Marc-Andre
name: Delbrassinne, Laurence
name: Denayer, Sarah
name: Zeleny, Reinhard
name: Schimmel, Heinz
name: Åstot, Crister
name: Dorner, Brigitte
name: Rummel, Andreas
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2015
Subjects: subject: characterization
subject: reference material
subject: botulinum neurotoxin
subject: recombinant expression
subject: specific activity
subject: mass spectrometric identification
subject: 610 Medizin

description: The detection and identification of botulinum neurotoxins (BoNT) is complex due to the existence of seven serotypes, derived mosaic toxins and more than 40 subtypes. Expert laboratories currently use different technical approaches to detect, identify and quantify BoNT, but due to the lack of (certified) reference materials, analytical results can hardly be compared. In this study, the six BoNT/A1–F1 prototypes were successfully produced by recombinant techniques, facilitating handling, as well as improving purity, yield, reproducibility and biosafety. All six BoNTs were quantitatively nicked into active di-chain toxins linked by a disulfide bridge. The materials were thoroughly characterized with respect to purity, identity, protein concentration, catalytic and biological activities. For BoNT/A1, B1 and E1, serotypes pathogenic to humans, the catalytic activity and the precise protein concentration were determined by Endopep-mass spectrometry and validated amino acid analysis, respectively. In addition, BoNT/A1, B1, E1 and F1 were successfully detected by immunological assays, unambiguously identified by mass spectrometric-based methods, and their specific activities were assigned by the mouse LD50 bioassay. The potencies of all six BoNT/A1–F1 were quantified by the ex vivo mouse phrenic nerve hemidiaphragm assay, allowing a direct comparison. In conclusion, highly pure recombinant BoNT reference materials were produced, thoroughly characterized and employed as spiking material in a worldwide BoNT proficiency test organized by the EQuATox consortium.
Additional file 1 of Intrauterine growth pattern in Butajira HDSS, Southern Ethiopia: BUNMAP pregnancy cohort
Creators: name: Mengistu, Yalemwork G.
name: Hailemariam, Damen
name: Roro, Meselech A.
name: Endris, Bilal S.
name: Tesfamariam, Kokeb
name: Gebreyesus, Seifu H.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology

description: Additional file 1: S Table 1. Growth chart for fetal abdominal circumference, Butajira Ethiopia, 2018-2019.
Additional file 1 of eSVD-DE: cohort-wide differential expression in single-cell RNA-seq data using exponential-family embeddings
Creators: name: Lin, Kevin Z.
name: Qiu, Yixuan
name: Roeder, Kathryn
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. High-level description on what is statistically challenging about doing differential expression testing after denoising a datset, simulation details and results, and supplemental details of the lung, colon, and brain analyses, and supplemental figures A1-F12.
sj-pdf-2-smm-10.1177_09622802211025992 - Supplemental material for Statistical methods for analysis of combined biomarker data from multiple nested case–control studies
Creators: name: Cheng, Chao
name: Sloan, Abigail
name: Wang, Molin
Publisher: name: SAGE Journals
Year: 2021
Subjects: Health and Community Services
Nursing not elsewhere classified
Sociological Methodology and Research Methods

description: Supplemental material, sj-pdf-2-smm-10.1177_09622802211025992 for Statistical methods for analysis of combined biomarker data from multiple nested case–control studies by Chao Cheng, Abigail Sloan and Molin Wang in Statistical Methods in Medical Research
PROGRESS TOWARD THE FESHBACH ASSOCIATION OF LITHIUM AND CESIUM ATOMS IN OPTICAL TWEEZER ARRAYS
Creators: name: Peana, David
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 340699
subject: Physical chemistry not elsewhere classified
classificationCode: 510299
subject: Atomic, molecular and optical physics not elsewhere classified

description: Abstract: The field of singly-trapped ultracold molecules has expanded rapidly in the past few years. With the introduction of fast tweezer rearrangement and the demonstrated viability of ground-state preparation by magneto-association coupled with STIRAP, powerful and robust arrays of ultracold molecules for quantum information science are finally being realized after decades of research. This dissertation primarily discusses the engineering associated with the conventional path toward creating arrays of LiCs molecules trapped in optical tweezers. Scientific results of the successful trapping and sub-doppler cooling of both atoms to release-recapture temperatures of less than 100uK are discussed. Discussed is also recent unpublished work focusing on atomic state preparation in optical tweezers, merging of the two species, and observation of Feshbach resonances of the pairs of atoms.
sj-pdf-2-jdr-10.1177_00220345211000629 – Supplemental material for 3D-Printed Polycaprolactone Reinforced Hydrogel as an Artificial TMJ Disc
Creators: name: Jiang, N.
name: Yang, Y.
name: Zhang, L.
name: Jiang, Y.
name: Wang, M.
name: Zhu, S.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-pdf-2-jdr-10.1177_00220345211000629 for 3D-Printed Polycaprolactone Reinforced Hydrogel as an Artificial TMJ Disc by N. Jiang, Y. Yang, L. Zhang, Y. Jiang, M. Wang and S. Zhu in Journal of Dental Research
sj-pdf-2-bbi-10.1177_11779322211030364 – Supplemental material for DEELIG: A Deep Learning Approach to Predict Protein-Ligand Binding Affinity
Creators: name: Ahmed, Asad
name: Mam, Bhavika
name: Sowdhamini, Ramanathan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, sj-pdf-2-bbi-10.1177_11779322211030364 for DEELIG: A Deep Learning Approach to Predict Protein-Ligand Binding Affinity by Asad Ahmed, Bhavika Mam and Ramanathan Sowdhamini in Bioinformatics and Biology Insights
CHARACTERIZATION OF INTERFACIAL ENERGY OF THIN FILMS THROUGH CURRENT INDUCED DIFFUSIVE INTERFACIAL VOIDING
Creators: name: Singh, Yuvraj
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Electromigration in thin films is a well known failure mode for scaled microelectronics. While our understanding of electromigration physics has improved immensely in the last few decades, there are still some gaps in literature. In particular, the influence of interfaces on the mass transport rate is not well understood. Through reliability studies conducted on passivated metals films, marked improvement in electromigration lifetimes was observed. Specifically, some choices of materials for passivation appear to perform better than others. Qualitatively this improvement in electromigration performance is attributed to surface adhesion. However, a theoretical connection is largely missing in the literature. Lane et al. through in-situ electromigration experiments and separate interfacial debond experiments on sandwich specimens showed that a correlation exists between the void growth rate and the debond energy. However, a fundamental understanding of the relation between the two is missing. In this study we explore the connection between interfacial adhesion and void growth in a current driven system. Several experiments with varying test conditions are carried out on Blech-like test structures with different capping layers. The influence of these capping layers is captured through direct void growth measurements. Comparison of activation energy associated with electromigration was made against existing literature. It was found to be consistent with values reported for surface/interface dominated diffusion mechanisms. Further, an extension is proposed to the phase growth relations derived in existing literature to include the effect of surface adhesion. Interfacial adhesion energy ratios are extracted from the electromigration experiments for two of the test structures (Cu-Ta and Cu-SiNx) tested in this study. This ratio is compared to values reported in literature for the two interfaces and they show good agreement with experimental data.
sj-pdf-1-sax-10.1177_10790632211024241 – Supplemental material for Automaticity of Early Sexual Attention: An Event-Related Potential Study
Creators: name: Ziogas, Anastasios
name: Habermeyer, Benedikt
name: Kawohl, Wolfram
name: Habermeyer, Elmar
name: Mokros, Andreas
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-sax-10.1177_10790632211024241 for Automaticity of Early Sexual Attention: An Event-Related Potential Study by Anastasios Ziogas, Benedikt Habermeyer, Wolfram Kawohl, Elmar Habermeyer and Andreas Mokros in Sexual Abuse: A Journal of Research and Treatment
sj-pdf-1-jpc-10.1177_21501327211029816 – Supplemental material for The Impact of a Yearlong Diabetes Prevention Program-Based Lifestyle Intervention on Cardiovascular Health Metrics
Creators: name: Devaraj, Susan M.
name: Rockette-Wagner, Bonny
name: Miller, Rachel G.
name: Arena, Vincent C.
name: Napoleone, Jenna M.
name: Conroy, Molly B.
name: Kriska, Andrea M.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-pdf-1-jpc-10.1177_21501327211029816 for The Impact of a Yearlong Diabetes Prevention Program-Based Lifestyle Intervention on Cardiovascular Health Metrics by Susan M. Devaraj, Bonny Rockette-Wagner, Rachel G. Miller, Vincent C. Arena, Jenna M. Napoleone, Molly B. Conroy and Andrea M. Kriska in Journal of Primary Care & Community Health
First report of two complete Clostridium chauvoei genome sequences and detailed in silico genome analysis
Creators: name: Thomas, Prasad
name: Semmler, Torsten
name: Eichhorn, Inga
name: Lübke-Becker, Antina
name: Werckenthin, Christiane
name: Abdel-Glil, Mostafa Y.
name: Wieler, Lothar H.
name: Neubauer, Heinrich
name: Seyboldt, Christian
Publisher: name: Robert Koch-Institut
Year: 2017
Subjects: subject: Clostridium chauvoei
subject: Complete circular genomes
subject: Spo0A
subject: CRISPR
subject: fliC
subject: 610 Medizin

description: Clostridium (C.) chauvoei is a Gram-positive, spore forming, anaerobic bacterium. It causes black leg in ruminants, a typically fatal histotoxic myonecrosis. High quality circular genome sequences were generated for the C. chauvoei type strain DSM 7528T (ATCC 10092T) and a field strain 12S0467 isolated in Germany. The origin of replication (oriC) was comparable to that of Bacillus subtilis in structure with two regions containing DnaA boxes. Similar prophages were identified in the genomes of both C. chauvoei strains which also harbored hemolysin and bacterial spore formation genes. A CRISPR type I-B system with limited variations in the repeat number was identified. Sporulation and germination process related genes were homologous to that of the Clostridia cluster I group but novel variations for regulatory genes were identified indicative for strain specific control of regulatory events. Phylogenomics showed a higher relatedness to C. septicum than to other so far sequenced genomes of species belonging to the genus Clostridium. Comparative genome analysis of three C. chauvoei circular genome sequences revealed the presence of few inversions and translocations in locally collinear blocks (LCBs). The species genome also shows a large number of genes involved in proteolysis, genes for glycosyl hydrolases and metal iron transportation genes which are presumably involved in virulence and survival in the host. Three conserved flagellar genes (fliC) were identified in each of the circular genomes. In conclusion this is the first comparative analysis of circular genomes for the species C. chauvoei, enabling insights into genome composition and virulence factor variation.
Radiation by Moving Charges
Creators: name: Geloni, Gianluca
name: Kocharyan, Vitali
name: Saldin, Evgeni
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017

description: It is generally accepted that the dynamics of relativistic particles in the lab frame can be described by taking into account the relativistic dependence of the particles momenta on the velocity, with no reference to Lorentz transformations. The electrodynamics problem can then be treated within a 'single inertial frame' description. To evaluate radiation fields from moving charged particles we need their velocities and positions as a function of the lab frame time t. The relativistic motion of a particle in the lab frame is described by Newton's second law corrected for the relativistic dependence of the particle momentum on the velocity. In all standard derivations the trajectories in the source part of the usual Maxwell's equations are identified with the trajectories $\vec{x}(t)$ calculated by using the 'corrected' Newton's second law. This way of coupling fields and particles is considered correct. We argue that this procedure needs to be changed by demonstrating a counterintuitive: the results of conventional theory of radiation by relativistically moving charges are not consistent with the principle of relativity. The trajectory of a particle in the lab frame consistent with the usual Maxwell's equations, is found by solving the dynamics equation in manifestly covariant form, with the proper time $\tau$ used to parameterize the particle world-line in space-time. We find a difference between the 'true' particle trajectory $\vec{x}(t)$ calculated or measured in the conventional way, and the covariant particle trajectory $\vec{x}_{cov}(t)$ calculated by projecting the world-line to the lab frame and using t to parameterize the trajectory curve. The difference is due to a choice of convention, but only $\vec{x}_{cov}(t)$ is consistent with the usual Maxwell's equations: therefore, a correction of the conventional synchrotron-cyclotron radiation theory is required.
MA'MURIY HUQUQBUZARLIK TO'G'RISIDAGI ISHLARNI YURITISH JARAYONIDAGI KAMCHILIKLAR
Creators: name: Abdullaev, Ilxom
Publisher: name: Zenodo
Year: 2024

description: Mazkur maqolani yozishdan maqsad hozirgi kunda amalyot jarayonida mamuriy huquqbuzarliklar to’g’risidagi ishlarni yuritish jarayonidagi yuzaga keladigan muammo kamchiliklarni aniqlash hamda ularni bartaraf etishdan iborat.
Supplemental Material, sj-pdf-2-tva-10.1177_15248380211029410 - Prevalence of Physical Violence Against Brazilian Women: Systematic Review and Meta-Analysis
Creators: name: Nakamura, Isabella Bagni
name: Silva, Marcus Tolentino
name: Garcia, Leila Posenato
name: Galvao, Tais Freire
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-2-tva-10.1177_15248380211029410 for Prevalence of Physical Violence Against Brazilian Women: Systematic Review and Meta-Analysis by Isabella Bagni Nakamura, Marcus Tolentino Silva, Leila Posenato Garcia and Tais Freire Galvao in Trauma, Violence, & Abuse
Supplemental Material, sj-pdf-1-tva-10.1177_15248380211030235 - Risk and Protective Factors Associated With Intimate Partner Violence Against Chinese Women: A Systematic Review
Creators: name: Cao, Jiepin
name: Lee, Chi-Young
name: Liu, Xu
name: Gonzalez-Guarda, Rosa M.
Publisher: name: SAGE Journals
Year: 2021
Subjects: Criminology not elsewhere classified

description: Supplemental Material, sj-pdf-1-tva-10.1177_15248380211030235 for Risk and Protective Factors Associated With Intimate Partner Violence Against Chinese Women: A Systematic Review by Jiepin Cao, Chi-Young Lee, Xu Liu and Rosa M. Gonzalez-Guarda in Trauma, Violence, & Abuse
Can Antiretroviral Drugs Be Used to Treat Porcine Endogenous Retrovirus (PERV) Infection after Xenotransplantation?
Creators: name: Denner, Joachim
Publisher: name: Robert Koch-Institut
Year: 2017
Subjects: subject: porcine endogenous retroviruses
subject: PERV
subject: antiretroviral drugs
subject: reverse transcriptase
subject: integrase
subject: 610 Medizin

description: Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs; they are released as infectious particles, and under certain conditions they can infect human cells. Therefore, they represent a risk when pigs are used as sources of cells, tissues, or organs for xenotransplantation. Xenotransplantation is under development due to the increasing shortage of human transplants. Whereas most porcine microorganisms which may be able to induce a disease (zoonosis) in the transplant recipient can be eliminated, this is not possible in the case of PERVs. Antiretroviral drugs which had been developed for the treatment of human immunodeficiency virus-1 (HIV-1) infections have been tested in vitro for their efficacy in inhibiting PERV replication. Inhibitors of the viral reverse transcriptase and of the integrase have been found effective. The most effective inhibitor of the reverse transcriptase was azidothymidine (AZT); the integrase inhibitors were the most potent inhibitors of PERV. Although in the past PERV transmission has not been observed after experimental or clinical xenotransplantation of pig cells or organs, and although PERVs may one day be inactivated in pigs by genome editing using CRISPR/Cas, knowing which antiretroviral drugs can effectively restrict PERV infection will still be important.
Rethinking and researching the physical meaning of the standard linear solid model in viscoelasticity
Creators: name: Lin, Che-Yu
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Despite the common use of the standard linear solid model (SLSM) in viscoelasticity, the physical significance as well as the difference between the Maxwell and Kelvin forms of SLSM are still not clear. This paper demonstrates that each parameter of those two models has its specific physical meaning, and introduces the relationships allowing the transformations between those parameters. Regardless of their physical significance, those two models are equivalent in terms of their mathematical properties. Hence, no matter which model is chosen, consistent analysis results can always be obtained as long as the physical meaning of each parameter is accurately interpreted.
Identification of Polo-like kinases as potential novel drug targets for influenza A virus
Creators: name: Pohl, Marie O.
name: Recum-Knepper, Jessica Von
name: Rodriguez-Frandsen, Ariel
name: Lanz, Caroline
name: Yángüez, Emilio
name: Soonthornvacharin, Stephen
name: Wolff, Thorsten
name: Chanda, Sumit K.
name: Stertz, Silke
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: 610 Medizin

description: In recent years genome-wide RNAi screens have revealed hundreds of cellular factors required for influenza virus infections in human cells. The long-term goal is to establish some of them as drug targets for the development of the next generation of antivirals against influenza. We found that several members of the polo-like kinases (PLK), a family of serine/threonine kinases with well-known roles in cell cycle regulation, were identified as hits in four different RNAi screens and we therefore studied their potential as drug target for influenza. We show that knockdown of PLK1, PLK3, and PLK4, as well as inhibition of PLK kinase activity by four different compounds, leads to reduced influenza virus replication, and we map the requirement of PLK activity to early stages of the viral replication cycle. We also tested the impact of the PLK inhibitor BI2536 on influenza virus replication in a human lung tissue culture model and observed strong inhibition of virus replication with no measurable toxicity. This study establishes the PLKs as potential drug targets for influenza and contributes to a more detailed understanding of the intricate interactions between influenza viruses and their host cells.
Measurement of $D^*$ Production in Diffractive Deep Inelastic Scattering at HERA
Creators: name: Andreev, V.
name: Baghdasaryan, A.
name: Begzsuren, K.
name: Belousov, A.
name: Bolz, A.
name: Boudry, V.
name: Brandt, G.
name: Brisson, V.
name: Britzger, D.
name: Buniatyan, A.
name: Bylinkin, A.
name: Bystritskaya, L.
name: Campbell, A. J.
name: Cantun Avila, K. B.
name: Cerny, K.
name: Chekelian, V.
name: Contreras, J. G.
name: Cvach, J.
name: Dainton, J. B.
name: Daum, K.
name: Diaconu, C.
name: Dobre, M.
name: Dodonov, V.
name: Eckerlin, G.
name: Egli, S.
name: Elsen, E.
name: Favart, L.
name: Fedotov, A.
name: Feltesse, J.
name: Ferencei, J.
name: Fleischer, M.
name: Fomenko, A.
name: Gabathuler, E.
name: Gayler, J.
name: Ghazaryan, S.
name: Goerlich, L.
name: Gogitidze, N.
name: Gouzevitch, M.
name: Grab, C.
name: Grebenyuk, A.
name: Greenshaw, T.
name: Grindhammer, G.
name: Haidt, D.
name: Henderson, R. C. W.
name: Hladký, J.
name: Hoffmann, D.
name: Horisberger, R.
name: Hreus, T.
name: Huber, F.
name: Jacquet, M.
name: Jansová, M.
name: Janssen, X.
name: Jung, A.
name: Jung, H.
name: Kapichine, M.
name: Katzy, J.
name: Kiesling, C.
name: Klein, M.
name: Kleinwort, C.
name: Kogler, R.
name: Kostka, P.
name: Kretzschmar, J.
name: Krücker, D.
name: Krüger, K.
name: Landon, M. P. J.
name: Lange, W.
name: Laycock, P.
name: Lebedev, A.
name: Levonian, S.
name: Lipka, K.
name: List, B.
name: List, J.
name: Lobodzinski, B.
name: Malinovski, E.
name: Martyn, H.-U.
name: Maxfield, S. J.
name: Mehta, A.
name: Meyer, A. B.
name: Meyer, H.
name: Meyer, J.
name: Mikocki, S.
name: Morozov, A.
name: Müller, K.
name: Naumann, Th.
name: Newman, P. R.
name: Niebuhr, C.
name: Nowak, G.
name: Olsson, J. E.
name: Ozerov, D.
name: Pascaud, C.
name: Patel, G. D.
name: Perez, E.
name: Petrukhin, A.
name: Picuric, I.
name: Pirumov, H.
name: Pitzl, D.
name: Plačakytė, R.
name: Polifka, R.
name: Radescu, V.
name: Raicevic, N.
name: Ravdandorj, T.
name: Reimer, P.
name: Rizvi, E.
name: Robmann, P.
name: Roosen, R.
name: Rostovtsev, A.
name: Rotaru, M.
name: Šálek, D.
name: Sankey, D. P. C.
name: Sauter, M.
name: Sauvan, E.
name: Schmitt, S.
name: Schoeffel, L.
name: Schöning, A.
name: Sefkow, F.
name: Shushkevich, S.
name: Soloviev, Y.
name: Sopicki, P.
name: South, D.
name: Spaskov, V.
name: Specka, A.
name: Steder, M.
name: Stella, B.
name: Straumann, U.
name: Sykora, T.
name: Thompson, P. D.
name: Traynor, D.
name: Truöl, P.
name: Tsakov, I.
name: Tseepeldorj, B.
name: Valkárová, A.
name: Vallée, C.
name: Van Mechelen, P.
name: Vazdik, Y.
name: Wegener, D.
name: Wünsch, E.
name: Žáček, J.
name: Zhang, Z.
name: Žlebčík, R.
name: Zohrabyan, H.
name: Zomer, F.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017
Subjects: meson: production
factorization: collinear
cross section: measured
parton: density
rapidity: gap
higher-order: 1
diffraction
deep inelastic scattering
DESY HERA Stor
quark
charm
quantum chromodynamics
kinematics
fusion

description: Measurements of $D^{*}(2010)$ meson production in diffractive deep inelastic scattering $(5
RELACIONAMENTO CONJUGAL E VIOLÊNCIA: Uma análise sobre os impactos emocionais
Creators: name: Isabelly Rodrigues de Paula, Larissa
name: Juliana Araújo Saldanha, Luana
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 520505
subject: Social psychology

description: A presente pesquisa teve como objetivo discutir os impactos emocionais gerados na mulher em decorrência da violência doméstica. A metodologia utilizada foi de caráter qualitativo, classificada como sendo Exploratória e Transversal. O trabalho buscou ressaltar que a violência contra as mulheres pode vir a ser uma forma de expressão das relações sociais estabelecidas em torno da questão de gênero e que podem vir esta alicerçada no sistema patriarcal, no qual naturaliza a supremacia masculina atribuindo socialmente às mulheres o papel de submissão e obediência. Nessa perspectiva essa pesquisa objetivou analisar os impactos emocionais gerados na mulher vítima de agressão. A pesquisa foi realizada na cidade de Mossoró no estado do Rio Grande do Norte, município o qual manifesta compromisso na ampliação de medidas de proteção as vítimas de violência doméstica, através de projetos de prevenção e rede de proteção ao combate à violência contra as mulheres. Portanto, a realização da presente pesquisa partiu da necessidade de estudos voltados para a temática sobre a importância da análise dos impactos emocionais, no qual, visa contribuir e promover para a sociedade uma visão elaborada e consciente sobre essa temática. Com isso, observou-se que as entrevistadas relataram sentimento de medo e culpa e não reconhecimento de si mesmas. Sendo possível destacar que houve impactos emocionais, bem como, ansiedade e depressão na vida dessas mulheres. Assim, acredita-se que a presente pesquisa alcançou seu objetivo de analisar os impactos emocionais gerados na mulher vítima de agressão doméstica.
Breaking the waves: modelling the potential impact of Public Health measures to defer the epidemic peak of novel influenza A/H1N1
Creators: name: Heiden, Matthias An Der
name: Buchholz, Udo
name: Krause, Gérard
name: Kirchner, Göran
name: Claus, Hermann
name: Haas, Walter
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2009
Subjects: subject: Adult
subject: Human/epidemiology
subject: Humans
subject: Public Health
subject: Germany/epidemiology
subject: Models
subject: Child
subject: Sentinel Surveillance
subject: Family Characteristics
subject: Influenza A Virus
subject: Influenza
subject: Human/virology
subject: Statistical
subject: H1N1 Subtype
subject: 610 Medizin

description: Background: On June 11, 2009, the World Health Organization declared phase 6 of the novel influenza A/H1N1 pandemic. Although by the end of September 2009, the novel virus had been reported from all continents, the impact in most countries of the northern hemisphere has been limited. The return of the virus in a second wave would encounter populations that are still nonimmune and not vaccinated yet. We modelled the effect of control strategies to reduce the spread with the goal to defer the epidemic wave in a country where it is detected in a very early stage. Methodology/Principal findings: We constructed a deterministic SEIR model using the age distribution and size of the population of Germany based on the observed number of imported cases and the early findings for the epidemiologic characteristics described by Fraser (Science, 2009). We propose a two-step control strategy with an initial effort to trace, quarantine, and selectively give prophylactic treatment to contacts of the first 100 to 500 cases. In the second step, the same measures are focused on the households of the next 5,000 to 10,000 cases. As a result, the peak of the epidemic could be delayed up to 7.6 weeks if up to 30% of cases are detected. However, the cumulative attack rates would not change. Necessary doses of antivirals would be less than the number of treatment courses for 0.1% of the population. In a sensitivity analysis, both case detection rate and the variation of R0 have major effects on the resulting delay. Conclusions/Significance: Control strategies that reduce the spread of the disease during the early phase of a pandemic wave may lead to a substantial delay of the epidemic. Since prophylactic treatment is only offered to the contacts of the first 10,000 cases, the amount of antivirals needed is still very limited.
MULTI-FACTOR DESIGNED EXPERIMENTS FOR COMPUTATIONAL PERFORMANCE MEASUREMENT ANALYSIS (CPM&A) OF PARALLEL DISTRIBUTED BIG DATA SYSTEMS AND SPAMHAUS DATA ANALYSIS
Creators: name: Song, Yuying
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Statistics not elsewhere classified
Applied statistics

description: Big Data analysis is of great challenges in practice. The data set sizes will grow quickly. And analysing big dataset in a timely manner is critical. In fact, computational performance depends very heavily, not just on size, but on the computational complexity of the analytic routines used in the analysis. Datasets that have computational challenges have a very wide range of sizes. Furthermore, the hardware power available to the data analyst is also an important factor. Improvements in performance from better measurement and analysis can be provided for wide ranges of dataset size, computational complexity, and hardware power. In my first part of dissertation, I will develop an overall framework of practices that can provide guidance to big data platform performance measurement. It has two main impacts, one is to provide a rigorous and comprehensive performance experiment framework on computing methods and systems for big-data analytics by bringing the statistical thinking, the statistical experimental design, and the statistical modeling to the research community. The other is to enhance performance improvement by providing a much better understanding of performance.
In the second part of the dissertation, I will analyze a 1TB Spamhaus Blacklisted Data by applying Divide and Recombine on Hadoop. The spamhaus data was collected from the Stanford mirror of the Spamhaus Internet IP address and domain name blacklist site. The Spamhaus service classifies IP addresses and domain names as blacklisted or not based on many sources of information and many factors such as being a major conduit for spam. Queries are sent to the site about the status of an IP address or domain name, whether it is blacklisted or not, and if blacklisted the cause. The processed data consist of values of 13 variables for each of 13,178,080,366 queries during 8 months. Subject matter divisions will be carried out and the blacklisted properties will be analyzed. The data were analyzed on Professor Cleveland's 10-node cluster, wsc; it has a little over 1 TB of memory and 200 cores. An important property of the blacklisting and its cause were discovered.
sj-pdf-1-jad-10.1177_10870547211025610 – Supplemental material for Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Adult Laboratory Classroom Study of the Efficacy and Safety of PRC-063 (Extended-Release Methylphenidate) for the Treatment of ADHD
Creators: name: Childress, Ann
name: Cutler, Andrew J.
name: Marraffino, Andrea H.
name: Bhaskar, Sailaja
name: Donnelly, Graeme
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-jad-10.1177_10870547211025610 for Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Adult Laboratory Classroom Study of the Efficacy and Safety of PRC-063 (Extended-Release Methylphenidate) for the Treatment of ADHD by Ann Childress, Andrew J. Cutler, Andrea H. Marraffino, Sailaja Bhaskar and Graeme Donnelly in Journal of Attention Disorders
Aufgaben und Funktion der Ständigen Arbeitsgemeinschaft der Kompetenz- und Behandlungszentren für hochkontagiöse, lebensbedrohliche Erkrankungen
Creators: name: Gottschalk, René
name: Grünewald, Thomas
name: Biederbick, Walter
Publisher: name: Robert Koch-Institut
Year: 2009
Subjects: subject: StAKoB
subject: Kompetenzzentren
subject: Hochkontagiöse lebensbedrohliche Infektionskrankheiten
subject: medical competence and treatment centers
subject: highly contagious diseases
subject: 610 Medizin

description: Die Einschleppung von Tropenkrankheiten nach Deutschland wird durch den zunehmenden Ferntourismus und durch die Globalisierung wirtschaftlicher Aktivitäten zu einem immer häufiger auftretenden Problem für das Gesundheitswesen. Die vernetzte Struktur landkreis- und teilweise länderübergreifender Kompetenzzentren für hochkontagiöse lebensbedrohliche Infektionskrankheiten hat sich bewährt und gezeigt, dass durch die Verknüpfung von öffentlichem Gesundheitsdienst (ÖGD), klinischer Versorgung, laborgestützte Spezialdiagnostik, Feuerwehr/Rettungsdienst und Krankenhaushygiene auch auf zunächst unerwartete infektiologische Situationen schnell und professionell reagiert werden kann. Mit diesen Netzwerken, die sich in der Ständigen Arbeitsgemeinschaft der Kompetenz- und Behandlungszentren (StAKoB) zusammengeschlossen haben, verfügt Deutschland derzeit über ein weltweit einzigartiges Instrument zur Behandlung hochinfektiöser, lebensbedrohlicher Infektionskrankheiten. Im vorliegenden Beitrag werden die Ziele und die Struktur der StAKoB dargestellt.
description: The introduction of tropical diseases into Germany is becoming a more and more frequent public health problem due to increasing long distance travel and the globalization of economic activities. A network of centers of excellence for imported, highly contagious diseases has proven efficient and shown that the linking of public health service, clinical care, laboratory-based special diagnostics, ambulance service, and hospital hygiene can react quickly and professionally in even unexpected situations in clinical infectiology. These networks joined forces in the “Permanent Working Group of the Medical Competence and Treatment Centers“ (Ständigen Arbeitsgemeinschaft der Kompetenz- und Behandlungszentren, StAKoB). Not only in Germany but also worldwide, the StAKoB is a unique system for the treatment of imported highly contagious diseases. The goals and structure of the StAKoB are presented in this article.
Additional file 1 of Factors related to the mortality risk of severe hand, foot, and mouth diseases (HFMD): a 5-year hospital-based survey in Guangxi, Southern China
Creators: name: Peng, Yuanjun
name: He, Weitao
name: Zheng, Zhigang
name: Pan, Peijiang
name: Ju, Yu
name: Lu, Zhenwei
name: Liao, Yanyan
name: Wang, Hailong
name: Zhang, Chao
name: Wang, Jing
name: Jiang, Lina
name: Liang, Hao
name: Chen, Minmei
name: Ye, Li
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 1. Comparison of demographic data of patients between vaccinated and not vaccinated group.
sj-pdf-1-cps-10.1177_00104140211024313 – Supplemental Material for Can Conservatism Make Women More Vulnerable to Violence?
Creators: name: Araújo, Victor
name: Gatto, Malu A. C.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental Material, sj-pdf-1-cps-10.1177_00104140211024313 for Can Conservatism Make Women More Vulnerable to Violence? by Victor Araújo and Malu A. C. Gatto in Comparative Political Studies
HIV-Diagnostik: Zu wenige Tests bei Risikopersonen
Creators: name: Schmidt, Reinhold E.
name: Rockstroh, Jürgen
name: Marcus, Ulrich
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: AIDS-Diagnostik
subject: AIDS-Prävention
subject: Diagnosestellung
subject: HIV-Infektion
subject: 610 Medizin

description: Bislang geht die Initiative zu einer HIV-Diagnostik meist von den Testpersonen selbst aus – oft zu spät für einen optimalen Therapiebeginn bei Infizierten. Deshalb sollten Ärzte bei erhöhten Infektionsrisiken aktiv auf die Testmöglichkeit hinweisen.
Unusual Archives and Unconventional Autobiographies: Interpreting the Experience of Rural Women, 1940-1985
Creators: name: Stephens, Abby L.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: North American history

description: This study analyzes eleven collections created, saved, and preserved by rural Iowa women, during the middle of the twentieth-century to interpret change in the experience of rural American women, and consider their role in the preservation of historical evidence. Analysis of privately-held and institutional collections of calendars, journals, scrapbooks, notebooks, and club meeting records provides details of farm life, rural communities in transition, and the way collection creators conceptualized and enacted the identity of rural womanhood. In making decisions about which events to write down in a journal or clip-and-save from the local newspaper, these women “performed archivalness” in preserving their experience for family and community members and scholars. The women who created the collections considered in this study experienced a rural landscape altered by the continuation and aftermath of agricultural specialization, mechanization, and capital consolidation. These changes altered rural community systems, economies, and institutions reshaping the experience of rural womanhood, as women upheld and adjusted the norms and values that defined the rural way of life. This study takes a three-part approach to considering the eleven collections as case studies. Chapter two analyzes five of the collections as unconventional forms of autobiographical writing, finding that nowhere else were women truer to themselves and their experiences than in their daily writing. In journals or on calendars, these women wrote their life stories by recording the daily details of work, motherhood, and marriage, and occasionally providing subtle commentary on local and national events. Changes in women’s work, education, responsibilities in marriage and motherhood, and involvement in public life and civic affairs happened in gradual and rapid ways during the middle of the twentieth-century. The third chapter in this study analyzes the collections of three women who used their writing to document, prescribe, and promote notions of rural womanhood during this time of change. Chapter four provides a meditation on the relationship between evidence and history by examining the ways in which three women performed archivalness in creating their collections. Consideration of the means by which the collections have been saved, provides insight into the importance of everyday individuals in the preservation of historical evidence.
Supplemental Material, sj-pdf-1-vet-10.1177_03009858211025793 - Immunohistochemical evaluation of suspected oral malignant melanoma in cats
Creators: name: Saverino, Kelly M.
name: Durham, Amy C.
name: Kiupel, Matti
name: Reiter, Alexander M.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental Material, sj-pdf-1-vet-10.1177_03009858211025793 for Immunohistochemical evaluation of suspected oral malignant melanoma in cats by Kelly M. Saverino, Amy C. Durham, Matti Kiupel and Alexander M. Reiter in Veterinary Pathology
Death and Transfiguration in Static Staphylococcus epidermidis Cultures
Creators: name: Schaudinn, Christoph
name: Stoodley, Paul
name: Hall-Stoodley, Luanne
name: Gorur, Amita
name: Remis, Jonathan
name: Wu, Siva
name: Auer, Manfred
name: Hertwig, Stefan
name: Guerrero-Given, Debbie
name: Hu, Fen Ze
name: Ehrlich, Garth D.
name: Costerton, John William
name: Robinson, Douglas H.
name: Webster, Paul
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2014
Subjects: subject: Bacterial Adhesion
subject: Biofilms/growth & development
subject: Culture Techniques
subject: Staphylococcus epidermidis/cytology
subject: Staphylococcus epidermidis/physiology
subject: 610 Medizin

description: The overwhelming majority of bacteria live in slime embedded microbial communities termed biofilms, which are typically adherent to a surface. However, when several Staphylococcus epidermidis strains were cultivated in static liquid cultures, macroscopic aggregates were seen floating within the broth and also sedimented at the test tube bottom. Light- and electron microscopy revealed that early-stage aggregates consisted of bacteria and extracellular matrix, organized in sheet-like structures. Perpendicular under the sheets hung a network of periodically arranged, bacteria-associated strands. During the extended cultivation, the strands of a subpopulation of aggregates developed into cross-connected wall-like structures, in which aligned bacteria formed the walls. The resulting architecture had a compartmentalized appearance. In late-stage cultures, the wall-associated bacteria disintegrated so that, henceforth, the walls were made of the coalescing remnants of lysed bacteria, while the compartment-like organization remained intact. At the same time, the majority of strand-containing aggregates with associated culturable bacteria continued to exist. These observations indicate that some strains of Staphylococcus epidermidis are able to build highly sophisticated structures, in which a subpopulation undergoes cell lysis, presumably to provide continued access to nutrients in a nutrient-limited environment, whilst maintaining structural integrity.
sj-pdf-6-jrt-10.1177_20556683211012885 - Supplemental material for Novel integrative rehabilitation system for the upper extremity: Design and usability evaluation
Creators: name: Burdea, Grigore
name: Kim, Nam
name: Polistico, Kevin
name: Kadaru, Ashwin
name: Roll, Doru
name: Grampurohit, Namrata
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, sj-pdf-6-jrt-10.1177_20556683211012885 for Novel integrative rehabilitation system for the upper extremity: Design and usability evaluation by Grigore Burdea, Nam Kim, Kevin Polistico, Ashwin Kadaru, Doru Roll and Namrata Grampurohit in Journal of Rehabilitation and Assistive Technologies Engineering
Supplemental Material, sj-pdf-3-tva-10.1177_15248380211029410 - Prevalence of Physical Violence Against Brazilian Women: Systematic Review and Meta-Analysis
Creators: name: Nakamura, Isabella Bagni
name: Silva, Marcus Tolentino
name: Garcia, Leila Posenato
name: Galvao, Tais Freire
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-3-tva-10.1177_15248380211029410 for Prevalence of Physical Violence Against Brazilian Women: Systematic Review and Meta-Analysis by Isabella Bagni Nakamura, Marcus Tolentino Silva, Leila Posenato Garcia and Tais Freire Galvao in Trauma, Violence, & Abuse
Genome sequence and phenotypic analysis of a first German Francisella sp. isolate (W12-1067) not belonging to the species Francisella tularensis
Creators: name: Rydzewski, Kerstin
name: Schulz, Tino
name: Brzuszkiewicz, Elzbieta
name: Holland, Gudrun
name: Lück, Christian
name: Fleischer, Jens
name: Grunow, Roland
name: Heuner, Klaus
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2014
Subjects: subject: Germany
subject: Legionella
subject: Francisella isolate
subject: W12-1067
subject: Cooling tower
subject: Genome sequence
subject: Pathogenicity island FPI
subject: Environmental
subject: 610 Medizin

description: Background: Francisella isolates from patients suffering from tularemia in Germany are generally strains of the species F. tularensis subsp. holarctica. To our knowledge, no other Francisella species are known for Germany. Recently, a new Francisella species could be isolated from a water reservoir of a cooling tower in Germany. Results: We identified a Francisella sp. (isolate W12-1067) whose 16S rDNA is 99% identical to the respective nucleotide sequence of the recently published strain F. guangzhouensis. The overall sequence identity of the fopA, gyrA, rpoA, groEL, sdhA and dnaK genes is only 89%, indicating that strain W12-1067 is not identical to F. guangzhouensis. W12-1067 was isolated from a water reservoir of a cooling tower of a hospital in Germany. The growth optimum of the isolate is approximately 30°C, it can grow in the presence of 4–5% NaCl (halotolerant) and is able to grow without additional cysteine within the medium. The strain was able to replicate within a mouse-derived macrophage-like cell line. The whole genome of the strain was sequenced (~1.7 mbp, 32.2% G + C content) and the draft genome was annotated. Various virulence genes common to the genus Francisella are present, but the Francisella pathogenicity island (FPI) is missing. However, another putative type-VI secretion system is present within the genome of strain W12-1067. Conclusions: Isolate W12-1067 is closely related to the recently described F. guangzhouensis species and it replicates within eukaryotic host cells. Since W12-1067 exhibits a putative new type-VI secretion system and F. tularensis subsp. holarctica was found not to be the sole species in Germany, the new isolate is an interesting species to be analyzed in more detail. Further research is needed to investigate the epidemiology, ecology and pathogenicity of Francisella species present in Germany.