cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Regolith production and transport in the Susquehanna Shale Hills Critical Zone Observatory, Part 1: Insights from U-series isotopes
Creators: name: Brantley, S.
name: Chabaux, F.
name: West, N.
name: Ma, L.
name: Jin, L.,
name: Kirby, E.
Publisher: name: Blackwell Publishing Ltd
Year: 2013

description: To investigate the timescales of regolith formation on hillslopes with contrasting topographic aspect, we measured U-series isotopes in regolith profiles from two hillslopes (north facing versus south facing) within the east-west trending Shale Hills catchment in Pennsylvania. This catchment is developed entirely on the Fe-rich, Silurian Rose Hill gray shale. Hillslopes exhibit a topographic asymmetry: The north-facing hillslope has an average slope gradient of ~20°, slightly steeper than the south-facing hillslope (~15°). The regolith samples display significant U-series disequilibrium resulting from shale weathering. Based on the U-series data, the rates of regolith production on the two ridgetops are indistinguishable (40 ± 22 versus 45 ± 12 m/Ma). However, when downslope positions are compared, the regolith profiles on the south-facing hillslope are characterized by faster regolith production rates (50 ± 15 to 52 ± 15 m/Ma) and shorter durations of chemical weathering (12 ± 3 to 16 ± 5 ka) than those on the north-facing hillslope (17 ± 14 to 18 ± 13 m/Ma and 39 ± 20 to 43 ± 20 ka). The south-facing hillslope is also characterized by faster chemical weathering rates inferred from major element chemistry, despite lower extents of chemical depletion. These results are consistent with the influence of aspect on regolith formation at Shale Hills; we hypothesize that aspect affects such variables as temperature, moisture content, and evapotranspiration in the regolith zone, causing faster chemical weathering and regolith formation rates on the south-facing side of the catchment. The difference in microclimate between these two hillslopes is inferred to have been especially significant during the periglacial period that occurred at Shale Hills at least ~15 ka before present. At that time, the erosion rates may also have been different from those observed today, perhaps denuding the south-facing hillslope of regolith but not quite stripping the north-facing hillslope. An analysis of hillslope evolution and response timescales with a linear mass transport model shows that the current landscape at Shale Hills is not in geomorphologic steady state (i.e., so-called dynamic equilibrium) but rather is likely still responding to the climate shift from the Holocene periglacial to the modern, temperate conditions.
A comprehensive in silico and in vitro studies on quinizarin: a promising phytochemical derived from Rhizophora mucronata Lam
Creators: name: Sachithanandam, V.
name: Lalitha, P.
name: Parthiban, A.
name: Muthukumaran, Jayaraman
name: Jain, Monika
name: Misra, Ranjita
name: Mageswaran, T.
name: Sridhar, R.
name: Purvaja, R.
name: Ramesh, R.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Mangrove plants are a great source of phytomedicines, since from the beginning of human civilization and the origin of traditional medicines. In the present study, ten different mangrove leaf methanolic extracts were screened for the type of phytochemicals followed by assessing antimicrobial, anti-oxidant and anti-cancer activities. The efficient methanolic crude extract of Rhizospora mucornata was further purified and characterized for the presence of the bioactive compound. Based on UV-visible spectroscopy, FTIR, NMR and HRMS analysis, the bioactive compound was 1,4-dihydroanthraquinone; also termed as Quinizarin. This identified compound was potential in exhibiting antimicrobial, antioxidant, and cytotoxic activity. Quinizarin inhibited the growth of Bacillus cereus and Klebsiella aerogenes with minimum inhibitory concentration (MIC) of 0.78 and 1.5 mg/ml. The DPPH free radical scavenging assay revealed the maximum activity of 99.8% at the concentration of 200 µg/ml with an IC50 value of 12.67 ± 0.41 µg/ml. Cytotoxic assay against HeLa (cervical) and MDA-MB231(breast) cancer cell lines revealed IC50 values to be 4.60 ± 0.26 and 3.89 ± 0.15 µg/ml. Together the results of molecular docking and molecular dynamics simulation studies explained that Quinizarin molecule showed stronger binding affinity (−6.2 kcal/mol) and significant structural stability towards anti-apoptotic Bcl-2 protein. Thus, the study put forth the promising role of the natural molecule - Quinizarin isolated from R. mucornata in the formulation of therapeutic drugs against bacterial infections and cancer. Communicated by Ramaswamy H. Sarma
Love Your Data (Steward*): Research Data Management Support at the University of Vienna
Creators: name: Kalová, Tereza
name: Feichtinger, Michael
name: Bargmann, Monika
Publisher: name: Zenodo
Year: 2023
Subjects: data steward
data stewardship
research data management
University of Vienna

description: Slides from the online coffee lecture "Love Your Data (Steward*): Research Data Management Support at the University of Vienna" that took place on February 14, 2023.
Finite-temperature scaling of spin correlations in an experimental realization of the one-dimensional Ising quantum critical point
Creators: name: Hälg, M.
name: Hüvonen, D.
name: Guidi, T.
name: Quintero-Castro, D. L.
name: Boehm, M.
name: Regnault, L. P.
name: Hagiwara, M.
name: Zheludev, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Inelastic neutron scattering is used to study the finite-temperature scaling behavior of the local dynamic structure factor in the quasi-one-dimensional quantum antiferromagnet NTENP ($\text{Ni(N,N'-bis(3-aminopropyl)propane-1,3-diamine)(}μ\text{-NO}_2\text{)ClO}_4$), at its field-induced Ising quantum critical point. The validity and the limitations of the theoretically predicted scaling relations are tested.
(500964) Aaron-Fernandez Nunez
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Properties of M31. V: 298 Eclipsing Binaries from PAndromeda
Creators: name: Lee, C. -H.
name: Koppenhoefer, J.
name: Seitz, S.
name: Bender, R.
name: Riffeser, A.
name: Kodric, M.
name: Hopp, U.
name: Snigula, J.
name: Goessl, C.
name: Kudritzki, R. -P.
name: Burgett, W.
name: Chambers, K.
name: Hodapp, K.
name: Kaiser, N.
name: Waters, C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The goal of this work is to conduct a photometric study of eclipsing binaries in M31. We apply a modified box-fitting algorithm to search for eclipsing binary candidates and determine their period. We classify these candidates into detached, semi-detached, and contact systems using the Fourier decomposition method. We cross-match the position of our detached candidates with the photometry from Local Group Survey (Massey et al. 2006) and select 13 candidates brighter than 20.5 magnitude in V. The relative physical parameters of these detached candidates are further characterized with Detached Eclipsing Binary Light curve fitter (DEBiL) by Devor (2005). We will followup the detached eclipsing binaries spectroscopically and determine the distance to M31.
description: 19 pages, 7 figures, 1 table, ApJ in press
Anatomy of the AGN in NGC 5548: I. A global model for the broadband spectral energy distribution
Creators: name: Mehdipour, M.
name: Kaastra, J. S.
name: Kriss, G. A.
name: Cappi, M.
name: Petrucci, P. -O.
name: Steenbrugge, K. C.
name: Arav, N.
name: Behar, E.
name: Bianchi, S.
name: Boissay, R.
name: Branduardi-Raymont, G.
name: Costantini, E.
name: Ebrero, J.
name: Di Gesu, L.
name: Harrison, F. A.
name: Kaspi, S.
name: De Marco, B.
name: Matt, G.
name: Paltani, S.
name: Peterson, B. M.
name: Ponti, G.
name: Nuñez, F. Pozo
name: De Rosa, A.
name: Ursini, F.
name: de Vries, C. P.
name: Walton, D. J.
name: Whewell, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: An extensive multi-satellite campaign on NGC 5548 has revealed this archetypal Seyfert-1 galaxy to be in an exceptional state of persistent heavy absorption. Our observations taken in 2013-2014 with XMM-Newton, Swift, NuSTAR, INTEGRAL, Chandra, HST and two ground-based observatories have together enabled us to establish that this unexpected phenomenon is caused by an outflowing stream of weakly ionised gas (called the obscurer), extending from the vicinity of the accretion disk to the broad-line region. In this work we present the details of our campaign and the data obtained by all the observatories. We determine the spectral energy distribution of NGC 5548 from near-infrared to hard X-rays by establishing the contribution of various emission and absorption processes taking place along our line of sight towards the central engine. We thus uncover the intrinsic emission and produce a broadband continuum model for both obscured (average summer 2013 data) and unobscured ($
description: Accepted for publication in A&A, 19 pages, 13 figures
Protocolo-Use of anticholinergic agents for haloperidol extrapyramidal side effects. A systematic review.
Creators: name: García Chávez, Linda Daniela
name: Herrería Guamialamá, Karol Mishel
name: Bonilla Maila, Handerson Dilan
name: Tonato Chaguancallo, Erick Jordy
name: Albites Yanza, Gina Nathalia
name: Mena Armas, Carlos Alexanderes
name: Alomoto Llumitasig, Katy Marisol
name: Zúñiga Carrasco, Danny Raúl
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 320221
subject: Psychiatry (incl. psychotherapy)

description: Anticholinergic agents are commonly employed to mitigate extrapyramidal side effects induced by antipsychotic medications. The extrapyramidal side effects encompass a range of motor disturbances, such as dystonia, akathisia, parkinsonism, and tardive dyskinesia, which can significantly impair patients' quality of life. Haloperidol or other antipsychotics, while effective in treating psychiatric disorders, often trigger extrapyramidal side effects due to their impact on dopamine receptors in the brain's nigrostriatal pathway.Anticholinergics exert their therapeutic effects by antagonizing the action of acetylcholine, a neurotransmitter responsible for motor control and various bodily functions. By blocking excessive acetylcholine activity, anticholinergics help counteract the imbalance caused by increased dopamine blockade from antipsychotics. Commonly used anticholinergic agents include benztropine, biperiden, and procyclidine.
N-substituted benzenesulfonamide compounds: DNA binding properties and molecular docking studies
Creators: name: Güngör, Seyit Ali
name: Tümer, Mehmet
name: Köse, Muhammet
name: Erkan, Sultan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Benzenesulfonamide-based imine compounds 5–8 were prepared and screened for their binding properties to the FSdsDNA. The structures of synthesized compounds were elucidated by the spectroscopic and analytical methods. Compounds 5–8 were screened for their interactions with the FSdsDNA. Compound 8 showed the highest binding affinity to the FSdsDNA with intrinsic binding constant of 3.10 × 104 M−1. The compounds caused the quenching of the DNA–EB emission indicating displacement of EB (ethidium bromide) from the FSdsDNA. Finally, the binding interactions between the DNA and binder molecules 5–8 were examined by the molecular docking studies. The compounds locate approximately same region of the minor groove of DNA via hydrogen bonding contacts between the sulfonamide oxygen atoms and the DG10/DG16 nucleotides of DNA. Communicated by Ramaswamy H. Sarma
Relationship between outer forearc subsidence and plate boundary kinematics along the Northeast Japan convergent margin
Creators: name: Furlong, K.P.
name: Fisher, D.M.
name: Kirby, E.
name: Regalla, C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Tectonic erosion along convergent plate boundaries, whereby removal of upper plate material along the subduction zone interface drives kilometer-scale outer forearc subsidence, has been purported to explain the evolution of nearly half the world's subduction margins, including part of the history of northeast Japan. Here, we evaluate the role of plate boundary dynamics in driving forearc subsidence in northeastern Japan. A synthesis of newly updated analyses of outer forearc subsidence, the timing and kinematics of upper plate deformation, and the history of plate convergence along the Japan trench demonstrate that the onset of rapid fore-arc tectonic subsidence is contemporaneous with upper plate extension during the opening of the Sea of Japan and with an acceleration in convergence rate at the trench. In Plio-Quaternary time, relative uplift of the outer forearc is contemporaneous with contraction across the arc and a decrease in plate convergence rate. The coincidence of these changes across the forearc, arc, backarc system appears to require an explanation at the scale of the entire plate boundary. Similar observations along other western Pacific margins suggest that correlations between forearc subsidence and major changes in plate kinematics are the rule, rather than the exception. We suggest that a significant component of forearc subsidence at the northeast Japan margin is not the consequence of basal tectonic erosion, but instead reflects dynamic changes in plate boundary geometry driven by temporal variations in plate kinematics. If correct, this model requires a reconsideration of the mass balance and crustal recycling of continental crust at nonaccretionary margins. Key Points Forearc subsidence coeval with upper plate extension, increased convergence rate Regional forearc subsidence/uplift likely reflects plate boundary-scale dynamics Results imply basal tectonic erosion is less efficient than previously assumed
Immunoinformatics analysis to design novel epitope based vaccine candidate targeting the glycoprotein and nucleoprotein of Lassa mammarenavirus (LASMV) using strains from Nigeria
Creators: name: Abass, Ohilebo Abdulateef
name: Timofeev, Vladimir I.
name: Sarkar, Bishajit
name: Onobun, Desmond Odiamehi
name: Ogunsola, Samuel Olarewaju
name: Aiyenuro, Ademola Emmanuel
name: Aborode, Abdullahi Tunde
name: Aigboje, Adebayo Emmanuel
name: Omobolanle, Basheer Nabilat
name: Imolele, Anthony Goodwill
name: Abiodun, Alade Adebowale
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Lassa mammarenavirus (LASMV) is responsible for a specific type of acute viral hemorrhagic fever known as Lassa fever. Lack of effective treatments and counter-measures against the virus has resulted in a high mortality rate in its endemic regions. Therefore, in this study, a novel epitope-based vaccine has been designed using the methods of immunoinformatics targeting the glycoprotein and nucleoprotein of the virus. After numerous robust analyses, two CTL epitopes, eight HTL epitopes and seven B-cell epitopes were finally selected for constructing the vaccine. All these most promising epitopes were found to be antigenic, non-allergenic, nontoxic and non-human homolog, which made them suitable for designing the subunit vaccine. Furthermore, the selected T-cell epitopes which were found to be fully conserved across different isolates of the virus, were also considered for final vaccine construction. After that, numerous validation experiments, i.e. molecular docking, molecular dynamics simulation and immune simulation were conducted, which predicted that our designed vaccine should be stable within the biological environment and effective in combating the LASMV infection. In the end, codon adaptation and in silico cloning studies were performed to design a recombinant plasmid for producing the vaccine industrially. However, further in vitro and in vivo assessments should be done on the constructed vaccine to finally confirm its safety and efficacy. Communicated by Ramaswamy H. Sarma
Radiation from a collapsing object is manifestly unitary
Creators: name: Saini, Anshul
name: Stojkovic, Dejan
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The process of gravitational collapse excites the fields propagating in the background geometry and gives rise to thermal radiation. We demonstrate by explicit calculations that the density matrix corresponding to such radiation actually describes a pure state. While Hawking's leading order density matrix contains only the diagonal terms, we calculate the off-diagonal correlation terms. These correlations start very small, but then grow in time. The cumulative effect is that the correlations become comparable to the leading order terms and significantly modify the density matrix. While the trace of the Hawking's density matrix squared diverges from unity during the evolution, the trace of the total density matrix squared remains unity at all times and all frequencies. This implies that the process of radiation from a collapsing object is unitary.
description: typos corrected, difference between various frequencies (\omega_0, \bar{\omega}, \Omega) explained, plots updated, discussion expanded
The growth of northeastern Tibet and its relevance to large-scale continental geodynamics: A review of recent studies
Creators: name: Dayem, K.E.
name: Burbank, D.W.
name: Garzione, C.N.
name: Roe, G.H.
name: Clark, M.K.
name: Farley, K.A.
name: Wang, Z.-C.
name: Yuan, D.-Y.
name: Ge, W.-P.
name: Craddock, W.H.
name: Zhang, P.-Z.
name: Kirby, E.
name: Molnar, P.
name: Zhang, H.-P.
name: Hough, B.G.
name: Duvall, A.R.
name: Li, C.-Y.
name: Chen, Z.-W.
name: Zheng, W.-J.
name: Zheng, D.-W.
name: Champagnac, J.-D.
name: Lease, R.O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Recent studies of the northeastern part of the Tibetan Plateau have called attention to two emerging views of how the Tibetan Plateau has grown. First, deformation in northern Tibet began essentially at the time of collision with India, not 10-20 Myr later as might be expected if the locus of activity migrated northward as India penetrated the rest of Eurasia. Thus, the north-south dimensions of the Tibetan Plateau were set mainly by differences in lithospheric strength, with strong lithosphere beneath India and the Tarim and Qaidam basins steadily encroaching on one another as the region between them, the present-day Tibetan Plateau, deformed, and its north-south dimension became narrower. Second, abundant evidence calls for acceleration of deformation, including the formation of new faults, in northeastern Tibet since ~15 Ma and a less precisely dated change in orientation of crustal shortening since ~20 Ma. This reorientation of crustal shortening and roughly concurrent outward growth of high terrain, which swings from NNE-SSW in northern Tibet to more NE-SW and even ENE-WSW in the easternmost part of northeastern Tibet, are likely to be, in part, a consequence of crustal thickening within the high Tibetan Plateau reaching a limit, and the locus of continued shortening then migrating to the northeastern and eastern flanks. These changes in rates and orientation also could result from removal of some or all mantle lithosphere and increased gravitational potential energy per unit area and from a weakening of crustal material so that it could flow in response to pressure gradients set by evolving differences in elevation. Key Points The north-south limits of Tibet were set by lateral variations in strength Roughly 15 million years ago, deformation of NE Tibet accelerated Since 20-15 million years ago, the orientation of shortening rotated eastward
A Small Claims Court for the NLP: Judging Legal Text Classification Strategies With Small Datasets
Creators: name: Noguti, Mariana Yukari
name: Vellasques, Edduardo
name: Oliveira, Luiz Eduardo Soares
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Recent advances in language modelling has significantly decreased the need of labelled data in text classification tasks. Transformer-based models, pre-trained on unlabeled data, can outmatch the performance of models trained from scratch for each task. However, the amount of labelled data need to fine-tune such type of model is still considerably high for domains requiring expert-level annotators, like the legal domain. This paper investigates the best strategies for optimizing the use of a small labeled dataset and large amounts of unlabeled data and perform a classification task in the legal area with 50 predefined topics. More specifically, we use the records of demands to a Brazilian Public Prosecutor's Office aiming to assign the descriptions in one of the subjects, which currently demands deep legal knowledge for manual filling. The task of optimizing the performance of classifiers in this scenario is especially challenging, given the low amount of resources available regarding the Portuguese language, especially in the legal domain. Our results demonstrate that classic supervised models such as logistic regression and SVM and the ensembles random forest and gradient boosting achieve better performance along with embeddings extracted with word2vec when compared to BERT language model. The latter demonstrates superior performance in association with the architecture of the model itself as a classifier, having surpassed all previous models in that regard. The best result was obtained with Unsupervised Data Augmentation (UDA), which jointly uses BERT, data augmentation, and strategies of semi-supervised learning, with an accuracy of 80.7% in the aforementioned task.
(500959) Agnes Rachel Crawford
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
ORCID in Germany - A project driven success story (2023)
Creators: name: Schrader, Antonia
Publisher: name: Zenodo
Year: 2023
Subjects: ORCID
PID
Open Science
Persistent Identifier

description: This presentation was held in the course of the session "Communicating the value of PIDs and metadata: what’s in it for me, what’s in it for you?" of the NISOPlus 2023 Conference.
 In this presentation Antonia C. Schrader, Open Science Officer at the Helmholtz Open Science Office (Germany), told the story of the project ORCID DE, which is a project driven success story. She shared the experiences her project colleagues and she made during the two funding phases from 2016 until the end of 2022 and gave an outlook on what the team is going to work on next.
(500960) Alexander de Castro Crawford
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(500956) Frances [Howard] nee Mersh?
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Low-temperature thermochronometry along the Kunlun and Haiyuan Faults, NE Tibetan Plateau: Evidence for kinematic change during late-stage orogenesis
Creators: name: Duvall, A.R.
name: Clark, M.K.
name: Yuan, D.-Y.
name: Farley, K.A.
name: Kirby, E.
name: Li, C.
name: Craddock, W.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The Tibetan Plateau is a prime example of a collisional orogen with widespread strike-slip faults whose age and tectonic significance remain controversial. We present new low-temperature thermochronometry to date periods of exhumation associated with Kunlun and Haiyuan faulting, two major strike-slip faults within the northeastern margin of Tibet. Apatite and zircon (U-Th)/He and apatite fission-track ages, which record exhumation from ∼2 to 6 km crustal depths, provide minimum bounds on fault timing. Results from Kunlun samples show increased exhumation rates along the western fault segment at circa 12-8 Ma with a possible earlier phase of motion from ∼30-20 Ma, along the central fault segment at circa 20-15 Ma, and along the eastern fault segment at circa 8-5 Ma. Combined with previous studies, our results suggest that motion along the Haiyuan fault may have occurred as early as ∼15 Ma along the western/central fault segment before initiating at least by 10-8 Ma along the eastern fault tip. We relate an ∼250 km wide zone of transpressional shear to synchronous Kunlun and Haiyuan fault motion and suggest that the present-day configuration of active faults along the northeastern margin of Tibet was likely established since middle Miocene time. We interpret the onset of transpression to relate to the progressive confinement of Tibet against rigid crustal blocks to the north and expansion of crustal thickening to the east during the later stages of orogen development. Key Points Low-T thermochronometry dates periods of exhumation along NE Tibet faults Left-lateral faulting by mid-to-late Miocene along the Kunlun and Haiyuan Faults Shift to widespread lateral faulting in late stage of Tibet collisional history
Potentiality of Moringa oleifera against SARS-CoV-2: identified by a rational computer aided drug design method
Creators: name: Sen, Debanjan
name: Bhaumik, Samhita
name: Debnath, Pradip
name: Debnath, Sudhan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Coronavirus disease 2019 (COVID-19) has created a global human health crisis and economic setbacks. Lack of specific therapeutics and limited treatment options against COVID-19 has become a new challenge to identify potential hits in order to develop new therapeutics. One of the crucial life cycle enzymes of SARS-CoV-2 is main protease (Mpro), which plays a major role in mediating viral replication, makes it an attractive drug target. Virtual screening and three times repeated 100 ns molecular dynamics simulation of the best hits were performed to identify potential SARS-CoV-2 Mpro inhibitors from the available compounds of an antiviral plant Moringa oleifera. Three flavonoids isorhamnetin (1), kaempferol (2) and apigenin (3) showed good binding affinity, stable protein-ligand complexes throughout the simulation time, high binding energy and similar binding poses in comparison with known SARS-CoV-2 Mpro inhibitor baicalein. Therefore, different parts of M. oleifera may be emerged as a potential preventive and therapeutic against COVID-19. Communicated by Ramaswamy H. Sarma
Guido Bartorelli, Lisa Parolo (a cura di), Sirio Luginbühl: film sperimentali, Cluep, Padova 2018, pp. 315. ISBN 978-88-6787-891-8
Creators: name: Marchetti, Massimo
Publisher: name: Sezione di Lettere
Year: 2019

description: Sezione di Lettere, XIII (2018)
Ulysse et son double
Creators: name: Ropars, Jean-Michel
Publisher: name: Sezione di Lettere
Year: 2019
Subjects: double; Odysseus; Hermes; Thersites; Iros

description: Odysseus’s dual personnality, both positive and negative, reflects the dual personnality of the god Hermes, the god in which opposite forces are united. So he faces recurrently «doubles» reproducing the dark face of his contradictory personnality, namely Thersites and Dolon in the Iliad, and Iros in the Odyssey (it is also the ground for the final fight against the Suitors) : he hits them, hurts them or possibly eliminates them (in Plautus’s Amphitryon, Hermes-Mercurius does the same with his double, Sosius, Amphitryon’s servant). It looks like a kind of self sacrifice, commited against himself ; hence the underlying comparison of Odysseus with a sacrified deer.
description: Sezione di Lettere, XIII (2018)
The solar siblings in the Gaia era
Creators: name: Martínez-Barbosa, C. A.
name: Brown, A. G. A.
name: Zwart, S. Portegies
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We perform realistic simulations of the Sun's birth cluster in order to predict the current distribution of solar siblings in the Galaxy. We study the possibility of finding the solar siblings in the Gaia catalogue by using only positional and kinematic information. We find that the number of solar siblings predicted to be observed by Gaia will be around 100 in the most optimistic case, and that a phase space only search in the Gaia catalogue will be extremely difficult. It is therefore mandatory to combine the chemical tagging technique with phase space selection criteria in order to have any hope of finding the solar siblings.
description: To be published in the proceedings of the GREAT-ITN conference "The Milky Way Unravelled by Gaia: GREAT Science from the Gaia Data Releases", 1-5 December 2014, University of Barcelona, Spain, EAS Publications Series, eds Nicholas Walton, Francesca Figueras, and Caroline Soubiran
Un nuovo frammento delle Decretales di Papa Gregorio IX
Creators: name: Bertelli, Sandro
name: Ragazzini, Clio
Publisher: name: Sezione di Lettere
Year: 2019
Subjects: Latin Paleography; Codicology; Manuscripts and Early Printed Books; Pope Gregory IX’s Decretals; Medieval Canon Law.

description: This paper gives notice of a XIV century parchment fragment of pope Gregory IX’s Decretals found in the binding of a 1548 edition containing the first part of Felino Sandeo’s Commentary on five books of the Decretals, which is currently held by the Department of Law Library in Ferrara University with the marking III A 691.
description: Sezione di Lettere, XIII (2018)
Deciphering the effect of hydrophobicity on protein binding interaction in cobalt(II) complexes by multispectroscopic and computational methods
Creators: name: Bashir, Masrat
name: Yousuf, Imtiyaz
name: Arjmand, Farukh
name: Tabassum, Sartaj
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: In the present work, we report the synthesis, characterization of two cobalt complexes (1 and 2) and their HSA binding studies by multispectroscopic methods. Hirshfeld surfaces analysis and fingerprint plot analysis were carried out to identify intermolecular interactions viz., N–H···O, O–H···O and C–H···O linkages in crystal framework of the complexes. Density functional theory (DFT) studies were carried out to ascertain the electronic structure and molecular geometry of the complexes 1 and 2, and determine the localization of HOMO and LUMO in the complexes. A comparative in vitro interaction study of complex 1 and 2 with human serum albumin protein was carried out by employing UV-vis, fluorescence, circular dichroism, FTIR and molecular docking techniques. Interestingly, the HSA binding affinity of complex 2 was found to be more than complex 1 which was evidenced from the higher binding constant values owing to its strong hydrophobic topology. Further, a significant conformational change in microenvironment of HSA was noticed upon binding with complexes 1 and 2, nevertheless more perturbations were noticed in presence of complex 1. Molecular docking studies were carried out to validate the spectroscopic results and ascertain the preferential binding mode of complexes at the specific target site of HSA. Communicated by Ramaswamy H. Sarma The hydrophobicity of the two Co(II)-bipyridyl was modulated by changing their ligands The effect of change in hydrophobicity on their protein binding was investigated by multispectroscopic methods. Hirshfeld and DFT studies provided better insight about intermolecular interactions and electronic properties of complexes. The secondary structure of HSA was deeply perturbed upon interaction with the complexes Interestingly more pronounced effects were observed with complex 2 owing to its greater hydrophobic character.
(500957) Isabella [Howard]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Fra Ferrara e Napoli: percorsi bucolici
Creators: name: Montagnani, Cristina
Publisher: name: Sezione di Lettere
Year: 2019
Subjects: Boiardo; Sannazaro; De Jennaro; egloga

description: The essay takes into consideration Matteo Maria Boiardo’s eclogues in the vernacular and puts forward the hypothesis that it is possible to identify evidence of the influence left by the Estense text on subsequent Neapolitan bucolic production.
description: Sezione di Lettere, XIII (2018)
Muscle-strengthening exercise and public health assessment and monitoring
Creators: name: Shakespear-Druery, Jane
Publisher: name: University of Southern Queensland
Year: 2022
Subjects: Assessment
Measurement
Muscle-Strengthening Exercise
Public Health Surveillance
Physical Activity
Prevalence

description: Participation in muscle-strengthening exercise (MSE), e.g., using weight machines, free weights, or bodyweight, improves health and independently reduces the risks associated with many non-communicable diseases. While MSE is included in national/global physical activity guidelines, participation in MSE is low. Moreover, methods assessing MSE participation vary considerably leading to a potential misunderstanding of the relationship between MSE and health. Therefore, this thesis by publication aims to (i) review the assessment of MSE within public health surveillance (Study 1), (ii) examine relationships between MSE and health (Study 2 and 3), and (iii) describe the development, reliability/validity testing (Study 4) of a new survey instrument to assess multiple MSE participation components and influencing factors (Study 5). Study 1 comprised a systematic review of MSE surveillance studies (k=156). Secondary data analyses explored the relationship between adult MSE participation and five chronic health conditions (Study 2, N = 16,301); and hypertension (Study 3, N = 10,519). Study 4 describes the development of the Muscle-Strengthening Exercise Questionnaire (MSEQ) and its test-retest reliability (n = 85) and concurrent validity (n = 54). Factors influencing adult MSE participation (N = 435) were analysed in Study 5. Study 1 identified the under-representation of key MSE guideline components and highlighted the need for standardisation. Studies 2 and 3 showed, compared to doing none, adults who reported any MSE (~19%) had a reduced prevalence of having a chronic condition. Study 4 showed ‘acceptable’ reliability and validity of five key MSE components. Study 5 identified five behavioural factors that significantly influenced the odds of meeting the MSE guidelines. Overall, the data presented in this thesis increases the body of knowledge regarding the relationship between MSE and health. Moreover, this PhD has developed a new valid and reliable questionnaire to assess population-level MSE participation. Current findings could aid campaigns targeting populations most at risk of chronic disease and increase MSE uptake and adherence at the population level.
Heat-driven spin transport in a ferromagnetic metal
Creators: name: Xu, Yadong
name: Yang, Bowen
name: Tang, Chi
name: Jiang, Zilong
name: Schneider, Michael
name: Whig, Renu
name: Shi, Jing
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: As a non-magnetic heavy metal is attached to a ferromagnet, a vertically flowing heat-driven spin current is converted to a transverse electric voltage, which is known as the longitudinal spin Seebeck effect (SSE). If the ferromagnet is a metal, this voltage is also accompanied by voltages from two other sources, i.e. the anomalous Nernst effect in both the ferromagnet and the proximity-induced ferromagnetic boundary layer. By properly identifying and carefully separating those different effects, we find that in this pure spin current circuit the additional spin current drawn by the heavy metal generates another significant voltage by the ferromagnetic metal itself which should be present in all relevant experiments.
New incision rates along the Colorado River system based on cosmogenic burial dating of terraces: Implications for regional controls on Quaternary incision
Creators: name: Granger, D.E.
name: Cole, R.D.
name: Kirby, E.
name: Lazear, G.D.
name: Karlstrom, K.E.
name: Ouimet, W.B.
name: Darling, A.L.
name: Coblentz, D.D.
name: Aslan, A.
Publisher: name: Geological Society of America
Year: 2012

description: New cosmogenic burial and published dates of Colorado and Green river terraces are used to infer variable incision rates along the rivers in the past 10 Ma. A knickpoint at Lees Ferry separates the lower and upper Colorado River basins. We obtained an isochron cosmogenic burial date of 1.5 ± 0.13 Ma on a 190-m-high strath terrace near Bullfrog Basin, Utah (upstream of Lees Ferry). This age yields an average incision rate of 126+12/-10m/Ma above the knickpoint and is three times older than a cosmogenic surface age on the same terrace, suggesting that surface dates inferred by exposure dating may be minimum ages. Incision rates below Lees Ferry are faster, ~170m/Ma-230m/Ma, suggesting upstream knickpoint migration over the past several million years. A terrace at Hite (above Lees Ferry) yields an isochron burial age of 0.29 ± 0.17 Ma, and a rate of ~300-900m/Ma, corroborating incision acceleration in Glen Canyon. Within the upper basin, isochron cosmogenic burial dates of 1.48 ± 0.12 Ma on a 60 m terrace near the Green River in Desolation Canyon, Utah, and 1.2 ± 0.3 Ma on a 120 m terrace upstream of Flaming Gorge, Wyoming, give incision rates of 41± 3m/Ma and 100+33/-20m/Ma, respectively. In contrast, incision rates along the upper Colorado River are 150m/Ma over 0.64 and 10 Ma time frames. Higher incision rates, gradient, and discharge along the upper Colorado River relative to the Green River are consistent with differential rock uplift of the Colorado Rockies relative to the Colorado Plateau.
(500958) Emma Nunez
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Geomorphic and exhumational response of the Central American Volcanic Arc to Cocos Ridge subduction
Creators: name: Van Soest, M.
name: Morell, K.D.
name: Fisher, D.M.
name: Kirby, E.
Publisher: name: Blackwell Publishing Ltd
Year: 2012

description: The timing of collision of the Cocos Ridge at the Middle America Trench remains one of the outstanding questions in the tectonic evolution of the Central American convergent margin. New analyses of the tectonic geomorphology of the Cordillera de Talamanca, the extinct volcanic arc inboard of the Cocos Ridge, coupled with low temperature thermochronometry data, provide insight into the cooling and erosional history of the arc from late Miocene to present. We identify a low-relief surface at high elevation along the northeastern flanks of the range, which represents a relict erosional landscape cut across shallow plutonic rocks of the arc edifice. Longitudinal profiles of rivers on this surface are isolated from steep downstream sections by prominent knickzones that are interpreted to reflect a migrating wave of transient incision generated during differential rock uplift of the range. Reconstruction of pre-incision profiles suggests that rock uplift during the growth of the Cordillera de Talamanca is no greater than ∼2 km. This inference is corroborated by results from our apatite (U-Th)/He and apatite fission track analyses along an elevation transect on Mt. Chirripó, the highest mountain in the Cordillera de Talamanca. Low-temperature cooling ages overlap significantly with published high-temperature 40Ar/39Ar ages; the combined results imply that rapid cooling in the late Miocene was related to secular cooling of a shallow pluton, rather than exhumation. Our results imply that rapid incision along downstream channel segments, differential rock uplift, and growth of the Talamanca as a bivergent orogenic wedge associated with the onset of Cocos Ridge subduction are relatively young characteristics of the range. A review of previously published radiometric ages and revised plate reconstructions for the late Miocene further suggest that the cessation of arc volcanism in both the Cordillera de Talamanca and the Cordillera Central of western Panama was coeval with the initiation of oblique subduction of the Nazca plate during the late Miocene. Thus, we conclude that the cessation of arc volcanism in the late Miocene (>5-8 Ma) and the onset of Cocos Ridge collision (<3 Ma) are separate events that reflect recent changes in the configuration of the plate boundary system.