cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Preparation of stimuli responsive nanogels based on poly(N,N-diethylaminoethyl methacrylate) by a simple “surfactant-free” methodology
Creators: name: Manzanares-Guevara, Lizbeth A.
name: Licea-Claverie, Angel
name: Paraguay-Delgado, Francisco
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The synthesis of poly(N,N-diethylaminoethyl methacrylate)-core-polyethyleneglycol-shell (PDEAEM-core-PEG-shell) nanogels was achieved by using a “surfactant free” emulsion polymerization with the aid of commercially available polyethyleneglycol methyl ether methacrylates (PEGMA) as polymerizable stabilizers. By adjusting the synthetic parameters like the choice of initiator, crosslinker, PEGMA:DEAEM ratio and molecular weight of PEGMA, a series of core-shell nanogels varying in size (50-350 nm), PDEAEM content and pH/temperature responsive behavior were obtained in reactions taking only 60 min. The nanogels were used as nanoreactors for the preparation of gold nanoparticles (AuNPs). The PEGylated nanogels have a great potential to be used for diagnosis and therapy.
Algebraic hyperbolicity of the very general quintic surface in P 3
Creators: name: Coskun, Izzet
name: Riedl, Eric
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: We prove that a curve of degree dk on a very general surface of degree d≥5 in P 3 has geometric genus at least [Formula presented]+1. This gives a substantial improvement on the celebrated genus bounds of Geng Xu. As a corollary, we deduce the algebraic hyperbolicity of a very general quintic surface in P 3 , resolving a long-standing conjecture of Demailly. This completely determines which very general hypersurfaces in P 3 are algebraically hyperbolic.
Additional file 1 of The association between small airway dysfunction and aging: a cross-sectional analysis from the ECOPD cohort
Creators: name: Dai, Cuiqiong
name: Wu, Fan
name: Wang, Zihui
name: Peng, Jieqi
name: Yang, Huajing
name: Zheng, Youlan
name: Lu, Lifei
name: Zhao, Ningning
name: Deng, Zhishan
name: Xiao, Shan
name: Wen, Xiang
name: Xu, Jianwu
name: Huang, Peiyu
name: Zhou, Kunning
name: Wu, Xiaohui
name: Zhou, Yumin
name: Ran, Pixin
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Additional file 1: Table S1. Prevalence of SAD defined by CT, IOS, and spirometry over age in subjects with and without airflow limitation. Table S2. Multivariate binary logistic regression analysis of age and SAD risk in subjects with and without airflow limitation. Table S3. Multi-adjusted contributions of age to the severity of SAD among CT-defined SAD subjects from subjects without airflow limitation (n = 81). Table S4. Multi-adjusted contributions of age to the severity of SAD among CT-defined SAD subjects from subjects with airflow limitation (n = 468). Table S5. Multi-adjusted contributions of age to the severity of SAD among IOS-defined SAD subjects from subjects without airflow limitation (n = 207). Table S6. Multi-adjusted contributions of age to the severity of SAD among IOS-defined SAD subjects from subjects with airflow limitation (n = 396). Table S7. Multi-adjusted contributions of age to the severity of SAD among spirometry-defined SAD subjects from subjects without airflow limitation (n = 542). Table S8. Multi-adjusted contributions of age to the severity of SAD among spirometry-defined SAD subjects from subjects with airflow limitation (n = 830). Fig. S1. Flow diagram for stratification of 1859 subjects by airflow limitation and definitional methods. Fig. S2. Distribution of small airway abnormality indicated by markers from CT, IOS and spirometry over age stratification in subjects with and without airflow limitation.
Dynamic Response of Ionic Current in Conical Nanopores
Creators: name: Liu, Zhe
name: Ma, Long
name: Zhang, Hongwen
name: Zhuang, Jiakun
name: Man, Jia
name: Siwy, Zuzanna S.
name: Qiu, Yinghua
Publisher: name: arXiv
Year: 2024
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Ionic current rectification (ICR) of charged conical nanopores has various applications in fields including nanofluidics, bio-sensing, and energy conversion, whose function is closely related to the dynamic response of nanopores. The occurrence of ICR originates from the ion enrichment and depletion in conical pores, whose formation is found to be affected by the scanning rate of voltages. Here, through time-dependent simulations, we investigate the variation of ion current under electric fields and the dynamic formation of ion enrichment and depletion, which can reflect the response time of conical nanopores. The response time of nanopores when ion enrichment forms i.e. at the on state is significantly longer than that with the formation of ion depletion i.e. at the off state. Our simulation results reveal the regulation of response time by different nanopore parameters including the surface charge density, pore length, tip, and base radius, as well as the applied conditions such as the voltage and bulk concentration. The response time of nanopores is closely related to the surface charge density, pore length, voltage, and bulk concentration. Our uncovered dynamic response mechanism of the ionic current can guide the design of nanofluidic devices with conical nanopores, including memristors, ionic switches, and rectifiers.
description: 30 pages, 5 figures
Confidence Sets for Phylogenetic Trees
Creators: name: Willis, Amy
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Inferring evolutionary histories (phylogenetic trees) has important applications in biology, criminology, and public health. However, phylogenetic trees are complex mathematical objects that reside in a non-Euclidean space, which complicates their analysis. While our mathematical, algorithmic, and probabilistic understanding of phylogenies in their metric space is mature, rigorous inferential infrastructure is as yet undeveloped. In this manuscript, we unify recent computational and probabilistic advances to construct tree–valued confidence sets. The procedure accounts for both center and multiple directions of tree–valued variability. We draw on block replicates to improve testing, identifying the best supported most recent ancestor of the Zika virus, and formally testing the hypothesis that a Floridian dentist with AIDS infected two of his patients with HIV. The method illustrates connections between variability in Euclidean and tree space, opening phylogenetic tree analysis to techniques available in the multivariate Euclidean setting. Supplementary materials for this article are available online.
Fisher Exact Scanning for Dependency
Creators: name: Ma, Li
name: Jialiang Mao
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: We introduce a method—called Fisher exact scanning (FES)—for testing and identifying variable dependency that generalizes Fisher’s exact test on 2 × 2 contingency tables to R × C contingency tables and continuous sample spaces. FES proceeds through scanning over the sample space using windows in the form of 2 × 2 tables of various sizes, and on each window completing a Fisher’s exact test. Based on a factorization of Fisher’s multivariate hypergeometric (MHG) likelihood into the product of the univariate hypergeometric likelihoods, we show that there exists a coarse-to-fine, sequential generative representation for the MHG model in the form of a Bayesian network, which in turn implies the mutual independence (up to deviation due to discreteness) among the Fisher’s exact tests completed under FES. This allows an exact characterization of the joint null distribution of the p-values and gives rise to an effective inference recipe through simple multiple testing procedures such as Šidák and Bonferroni corrections, eliminating the need for resampling. In addition, FES can characterize dependency through reporting significant windows after multiple testing control. The computational complexity of FES is approximately linear in the sample size, which along with the avoidance of resampling makes it ideal for analyzing massive datasets. We use extensive numerical studies to illustrate the work of FES and compare it to several state-of-the-art methods for testing dependency in both statistical and computational performance. Finally, we apply FES to analyzing a microbiome dataset and further investigate its relationship with other popular dependency metrics in that context. Supplementary materials for this article are available online.
Assessing Tether Anchor Labeling and Usability in Pickup Trucks
Creators: name: Klinich, Kathleen D.
name: Manary, Miriam A.
name: Malik, Laura A.
name: Flannagan, Carol A.
name: Jermakian, Jessica S.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective: Investigate vehicle factors associated with child restraint tether use and misuse in pickup trucks and evaluate four labeling interventions designed to educate consumers on proper tether use. Methods: Volunteer testing was performed with 24 subjects and four different pickup trucks. Each subject performed eight child restraint installations among the four pickups using two forward-facing restraints: a Britax Marathon G4.1 and an Evenflo Triumph. Vehicles were selected to represent four different implementations of tether anchors among pickups: plastic loop routers (Chevrolet Silverado), webbing routers (Ram), back wall anchors (Nissan Frontier), and webbing routers plus metal anchors (Toyota Tundra). Interventions included a diagram label, QR Code linked to video instruction, coordinating text label, and contrasting text tag. Results: Subjects used the child restraint tether in 93 percent of trials. However, tether use was completely correct in only 9 percent of trials. An installation was considered functional if the subject attached the tether to a tether anchor and had a tight installation (ignoring routing and head restraint position); 28 percent of subjects achieved a functional installation. The most common installation error was attaching the tether hook to the anchor/router; directly behind the child restraint (near the top of the seatback) rather than placing the tether through the router and attaching it to the anchor in the adjacent seating position. The Nissan Frontier, with the anchor located on the back wall of the cab, had the highest rate of correct installations but also had the highest rate of attaching the tether to components other than the tether anchor (seat adjustor, child restraint storage hook, around head restraint). None of the labeling interventions had a significant effect on correct installation; not a single subject scanned the QR Code to access the video instruction. Subjects with the most successful installations spent extensive time reviewing the vehicle manuals. Conclusion: Current implementations of tether anchors among pickup trucks are not intuitive for child restraint installations, and alternate designs should be explored. Several different labeling interventions were ineffective at achieving correct tether use in pickup trucks.
Functional Graphical Models
Creators: name: Xinghao Qiao
name: Shaojun Guo
name: James, Gareth M.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Graphical models have attracted increasing attention in recent years, especially in settings involving high-dimensional data. In particular, Gaussian graphical models are used to model the conditional dependence structure among multiple Gaussian random variables. As a result of its computational efficiency, the graphical lasso (glasso) has become one of the most popular approaches for fitting high-dimensional graphical models. In this paper, we extend the graphical models concept to model the conditional dependence structure among p random functions. In this setting, not only is p large, but each function is itself a high-dimensional object, posing an additional level of statistical and computational complexity. We develop an extension of the glasso criterion (fglasso), which estimates the functional graphical model by imposing a block sparsity constraint on the precision matrix, via a group lasso penalty. The fglasso criterion can be optimized using an efficient block coordinate descent algorithm. We establish the concentration inequalities of the estimates, which guarantee the desirable graph support recovery property, that is, with probability tending to one, the fglasso will correctly identify the true conditional dependence structure. Finally, we show that the fglasso significantly outperforms possible competing methods through both simulations and an analysis of a real-world electroencephalography dataset comparing alcoholic and nonalcoholic patients.
RECENSIÓN: Rocío Velasco de Castro. El protectorado español en Marruecos en primera persona: Muhammad Ibn Azzuz Hakim
Creators: name: Hernández-Justo, T.
Publisher: name: Zenodo
Year: 2018

description: Recensión de la obra "El protectorado español en Marruecos en primera persona: Muhammad Ibn Azzuz Hakim", de Rocío Velasco de Castro.
Non-coding RNAs underlie genetic predisposition to breast cancer.
Creators: name: Moradi Marjaneh, Mahdi
name: Beesley, Jonathan
name: O'Mara, Tracy A
name: Mukhopadhyay, Pamela
name: Koufariotis, Lambros T
name: Kazakoff, Stephen
name: Hussein, Nehal
name: Fachal, Laura
name: Bartonicek, Nenad
name: Hillman, Kristine M
name: Kaufmann, Susanne
name: Sivakumaran, Haran
name: Smart, Chanel E
name: McCart Reed, Amy E
name: Ferguson, Kaltin
name: Saunus, Jodi M
name: Lakhani, Sunil R
name: Barnes, Daniel R
name: Antoniou, Antonis C
name: Dinger, Marcel E
name: Waddell, Nicola
name: Easton, Douglas F
name: Dunning, Alison M
name: Chenevix-Trench, Georgia
name: Edwards, Stacey L
name: French, Juliet D
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: BACKGROUND:Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the contribution of non-coding RNAs to complex traits is not clear. RESULTS:Using targeted RNA sequencing, we systematically annotated multi-exonic non-coding RNA (mencRNA) genes transcribed from 1.5-Mb intervals surrounding 139 breast cancer GWAS signals and assessed their contribution to breast cancer risk. We identify more than 4000 mencRNA genes and show their expression distinguishes normal breast tissue from tumors and different breast cancer subtypes. Importantly, breast cancer risk variants, identified through genetic fine-mapping, are significantly enriched in mencRNA exons, but not the promoters or introns. eQTL analyses identify mencRNAs whose expression is associated with risk variants. Furthermore, chromatin interaction data identify hundreds of mencRNA promoters that loop to regions that contain breast cancer risk variants. CONCLUSIONS:We have compiled the largest catalog of breast cancer-associated mencRNAs to date and provide evidence that modulation of mencRNAs by GWAS variants may provide an alternative mechanism underlying complex traits.
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0519
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0519, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0519, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
A comparative study of autistic and non-autistic women's experience of motherhood.
Creators: name: Pohl, A L
name: Crockford, S K
name: Blakemore, M
name: Allison, C
name: Baron-Cohen, S
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Autism
Parenting
Motherhood

description: Background:Autism is a lifelong neurodevelopmental difference and disability, yet there is limited research examining parenting in autistic mothers. Objective:To explore autistic mothers' experience of the perinatal period and parenthood. This includes pregnancy, childbirth, the postpartum period, self-perception of parenting strengths and weaknesses, communication with professionals in relation to one's child, mental health difficulties and the social experience of motherhood. It also includes disclosing one's diagnosis of autism in parenting contexts. Methods:We used a community-based participatory research model, and recruited an advisory panel, with whom we co-developed an anonymous, online survey for autistic mothers. The online survey was completed by autistic and non-autistic mothers, and we compared their responses using Chi-squared analysis. Sample:Autistic mothers (n = 355), and non-autistic mothers (n = 132), each of whom had at least one autistic child, were included in our final analysis. Results:There were differences in education, gender identity and age of mother at birth of first child. Autistic mothers were more likely to have experienced additional psychiatric conditions, including pre- or post-partum depression, and reported greater difficulties in areas such as multi-tasking, coping with domestic responsibilities and creating social opportunities for their child. They were also more likely to report feeling misunderstood by professionals, and reported greater anxiety, higher rates of selective mutism, and not knowing which details were appropriate to share with professionals. They were also more likely to find motherhood an isolating experience, to worry about others judging their parenting, or feel unable to turn to others for support in parenting. However, despite these challenges, autistic mothers were able to act in the best interest of their child, putting their child's needs first. Conclusions:Autistic mothers face unique challenges and the stigma associated with autism may further exacerbate communication difficulties. Greater understanding and acceptance amongst individuals who interact with autistic mothers is needed, and autistic mothers would benefit from additional and better-tailored support.
Fisher exact scanning for dependency
Creators: name: Ma, Li
name: Jialiang Mao
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: We introduce a method—called Fisher exact scanning (FES)—for testing and identifying variable dependency that generalizes Fisher's exact test on 2 × 2 contingency tables to R × C contingency tables and continuous sample spaces. FES proceeds through scanning over the sample space using windows in the form of 2 × 2 tables of various sizes, and on each window completing a Fisher's exact test. Based on a factorization of Fisher's multivariate hypergeometric (MHG) likelihood into the product of the univariate hypergeometric likelihoods, we show that there exists a coarse-to-fine, sequential generative representation for the MHG model in the form of a Bayesian network, which in turn implies the mutual independence (up to deviation due to discreteness) among the Fisher's exact tests completed under FES. This allows an exact characterization of the joint null distribution of the p-values and gives rise to an effective inference recipe through simple multiple testing procedures such as Šidák and Bonferroni corrections, eliminating the need for resampling. In addition, FES can characterize dependency through reporting significant windows after multiple testing control. The computational complexity of FES is approximately linear in the sample size, which along with the avoidance of resampling makes it ideal for analyzing massive data sets. We use extensive numerical studies to illustrate the work of FES and compare it to several state-of-the-art methods for testing dependency in both statistical and computational performance. Finally, we apply FES to analyzing a microbiome data set and further investigate its relationship with other popular dependency metrics in that context.
IZQUIERDO BRICHS, Ferran, ETHERINGTON, John y FELIU, Laura (eds.) (2017), Political Islam in a Time of Revolt, Palgrave Macmillan, Cham
Creators: name: Hernández-Justo, T.
Publisher: name: Zenodo
Year: 2022

description: Reseña de IZQUIERDO BRICHS, Ferran, ETHERINGTON, John y FELIU, Laura (eds.) (2017), Political Islam in a Time of Revolt, Palgrave Macmillan, Cham
title: ADCO, Cinquième cartulaire de Saint-Étienne de Dijon (1664), Cart. 28 (G 132), 258 folios, f. 00398
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00398, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00398, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Clustered CTCF binding is an evolutionary mechanism to maintain topologically associating domains.
Creators: name: Kentepozidou, Elissavet
name: Aitken, Sarah J
name: Feig, Christine
name: Stefflova, Klara
name: Ibarra-Soria, Ximena
name: Odom, Duncan T
name: Roller, Maša
name: Flicek, Paul
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Chromatin Architecture
Tads
Cross-species Analysis
Ctcf Binding Evolution

description: BACKGROUND:CTCF binding contributes to the establishment of a higher-order genome structure by demarcating the boundaries of large-scale topologically associating domains (TADs). However, despite the importance and conservation of TADs, the role of CTCF binding in their evolution and stability remains elusive. RESULTS:We carry out an experimental and computational study that exploits the natural genetic variation across five closely related species to assess how CTCF binding patterns stably fixed by evolution in each species contribute to the establishment and evolutionary dynamics of TAD boundaries. We perform CTCF ChIP-seq in multiple mouse species to create genome-wide binding profiles and associate them with TAD boundaries. Our analyses reveal that CTCF binding is maintained at TAD boundaries by a balance of selective constraints and dynamic evolutionary processes. Regardless of their conservation across species, CTCF binding sites at TAD boundaries are subject to stronger sequence and functional constraints compared to other CTCF sites. TAD boundaries frequently harbor dynamically evolving clusters containing both evolutionarily old and young CTCF sites as a result of the repeated acquisition of new species-specific sites close to conserved ones. The overwhelming majority of clustered CTCF sites colocalize with cohesin and are significantly closer to gene transcription start sites than nonclustered CTCF sites, suggesting that CTCF clusters particularly contribute to cohesin stabilization and transcriptional regulation. CONCLUSIONS:Dynamic conservation of CTCF site clusters is an apparently important feature of CTCF binding evolution that is critical to the functional stability of a higher-order chromatin structure.
Constraining gravitational-wave backgrounds from conversions into photons in the Galactic magnetic field
Creators: name: Lella, Alessandro
name: Calore, Francesca
name: Carenza, Pierluca
name: Mirizzi, Alessandro
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: High-frequency gravitational waves ($f \gtrsim 1$ MHz) may provide a unique signature for the existence of exotic physics. The lack of current and future gravitational-wave experiments sensitive at those frequencies leads to the need of employing different indirect techniques. Notably, one of the most promising one is constituted by graviton-photon conversions in magnetic fields. In this work, we focus on conversions of a gravitational-wave background into photons inside the Milky-Way magnetic field, taking into account the state-of-the-art models for both regular and turbulent components. We discuss how graviton-to-photon conversions may lead to imprints in the cosmic photon background spectrum in the range of frequencies $f\sim10^{9}-10^{26}\,$Hz, where the observed photon flux is widely explained by astrophysics emission models. Hence, the absence of any significant evidence for a diffuse photon flux induced by graviton-photon conversions allows us to set stringent constraints on the gravitational-wave strain $h_c$, strengthening current astrophysical bounds by $\sim1-2$ orders of magnitude in the whole range of frequencies considered.
description: 14 pages, 6 figures. Matches the version published on PRD. Changes: we added a further discussion of uncertainties on the constraints introduced
Confidence sets for phylogenetic trees
Creators: name: Willis, Amy
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Inferring evolutionary histories (phylogenetic trees) has important applications in biology, criminology and public health. However, phylogenetic trees are complex mathematical objects that reside in a non-Euclidean space, which complicates their analysis. While our mathematical, algorithmic, and probabilistic understanding of phylogenies in their metric space is mature, rigorous inferential infrastructure is as yet undeveloped. In this manuscript we unify recent computational and probabilistic advances to construct tree-valued confidence sets. The procedure accounts for both centre and multiple directions of tree-valued variability. We draw on block replicates to improve testing, identifying the best supported most recent ancestor of the Zika virus, and formally testing the hypothesis that a Floridian dentist with AIDS infected two of his patients with HIV. The method illustrates connections between variability in Euclidean and tree space, opening phylogenetic tree analysis to techniques available in the multivariate Euclidean setting.
Large magnetoresistance and first-order phase transition in antiferromagnetic single-crystalline EuAg$_4$Sb$_2$
Creators: name: Malick, Sudip
name: Świątek, Hanna
name: Bławat, Joanna
name: Singleton, John
name: Klimczuk, Tomasz
Publisher: name: arXiv
Year: 2024
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present the results of a thorough investigation of the physical properties of EuAg$_4$Sb$_2$ single crystals using magnetization, heat capacity, and electrical resistivity measurements. High-quality single crystals, which crystallize in a trigonal structure with space group $R\bar{3}m$, were grown using a conventional flux method. Temperature-dependent magnetization measurements along different crystallographic orientations confirm two antiferromagnetic phase transitions around $T_{N1}$ = 10.5 K and $T_{N2}$ = 7.5 K. Isothermal magnetization data exhibit several metamagnetic transitions below these transition temperatures. Antiferromagnetic phase transitions in EuAg$_4$Sb$_2$ are further confirmed by two sharp peaks in the temperature-dependent heat capacity data at $T_{N1}$ and $T_{N2}$, which shift to the lower temperature in the presence of an external magnetic field. Our systematic heat capacity measurements utilizing a long-pulse and single-slope analysis technique allow us to detect a first-order phase transition in EuAg$_4$Sb$_2$ at 7.5 K. The temperature-dependent electrical resistivity data also manifest two features associated with magnetic order. The magnetoresistance exhibits a broad hump due to the field-induced metamagnetic transition. Remarkably, the magnetoresistance keeps increasing without showing any tendency to saturate as the applied magnetic field increases, and it reaches $\sim$20000\% at 1.6 K and 60 T. At high magnetic fields, several magnetic quantum oscillations are observed, indicating a complex Fermi surface. A large negative magnetoresistance of about -55\% is also observed near $T_{N1}$. Moreover, the $H$-$T$ phase diagram constructed using magnetization, heat capacity, and magnetotransport data indicates complex magnetic behavior in EuAg$_4$Sb$_2$.
description: 10 pages, 6 figures
Infrastructure and Tools for Teaching Computing Throughout the Statistical Curriculum
Creators: name: Çetinkaya-Rundel, Mine
name: Rundel, Colin
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Hematology

description: Modern statistics is fundamentally a computational discipline, but too often this fact is not reflected in our statistics curricula. With the rise of big data and data science, it has become increasingly clear that students want, expect, and need explicit training in this area of the discipline. Additionally, recent curricular guidelines clearly state that working with data requires extensive computing skills and that statistics students should be fluent in accessing, manipulating, analyzing, and modeling with professional statistical analysis software. Much has been written in the statistics education literature about pedagogical tools and approaches to provide a practical computational foundation for students. This article discusses the computational infrastructure and toolkit choices to allow for these pedagogical innovations while minimizing frustration and improving adoption for both our students and instructors. Supplementary materials for this article are available online.
Supplementary material for: "Development of an Australasian laparoscopic sleeve gastrectomy curriculum: a content validation study"
Creators: name: Blackman, Ruth E
name: Hamdorf, Jeffrey M
Publisher: name: Zenodo
Year: 2022

description: Supplementary material for the article: "Development of an Australasian laparoscopic sleeve gastrectomy curriculum: a content validation study". Journal of Surgical Simulation 2022; 9: 31–35. https://doi.org/10.1102/2051-7726.2022.0004 Supplementary Table 1. Survey results.
VAFB-2006-08: Archaeological Survey of the Coastline and Lower Drainages, Vandenberg Air Force Base, Santa Barbara County, California
Creators: name: Lebow, Clayton G.
name: Ryan, Dina M.
Publisher: name: Applied Earthworks, Inc.
Year: 2006
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: Erosion
valueUri: https://core.tdar.org/browse/other-keyword/1533/erosion

description: This document is a report for Vandenberg Air Force Base pertaining to a Section 110 inventory specifically focused on sea cliff and erosional cut banks that were not the focus of the base-wide survey completed in the 1990s. It was a required deliverable that documents Æ’s archaeological survey of the coastline and waterways as specified in the scope of work. Following the introduction, Chapter 2 synthesizes the natural and cultural setting of Vandenberg AFB. Chapter 3 discusses survey methods, and Chapter 4 presents the survey results. Chapter 5 summarizes the project and offers management recommendations. Site records for newly discovered archaeological resources are included in Appendix A. New site records completed for previously documented sites are provided in Appendix B, and Appendix C contains updates for previously recorded sites.
Chromatin interactome mapping at 139 independent breast cancer risk signals.
Creators: name: Beesley, Jonathan
name: Sivakumaran, Haran
name: Moradi Marjaneh, Mahdi
name: Lima, Luize G
name: Hillman, Kristine M
name: Kaufmann, Susanne
name: Tuano, Natasha
name: Hussein, Nehal
name: Ham, Sunyoung
name: Mukhopadhyay, Pamela
name: Kazakoff, Stephen
name: Lee, Jason S
name: Michailidou, Kyriaki
name: Barnes, Daniel R
name: Antoniou, Antonis C
name: Fachal, Laura
name: Dunning, Alison M
name: Easton, Douglas F
name: Waddell, Nicola
name: Rosenbluh, Joseph
name: Möller, Andreas
name: Chenevix-Trench, Georgia
name: French, Juliet D
name: Edwards, Stacey L
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: BACKGROUND:Genome-wide association studies have identified 196 high confidence independent signals associated with breast cancer susceptibility. Variants within these signals frequently fall in distal regulatory DNA elements that control gene expression. RESULTS:We designed a Capture Hi-C array to enrich for chromatin interactions between the credible causal variants and target genes in six human mammary epithelial and breast cancer cell lines. We show that interacting regions are enriched for open chromatin, histone marks for active enhancers, and transcription factors relevant to breast biology. We exploit this comprehensive resource to identify candidate target genes at 139 independent breast cancer risk signals and explore the functional mechanism underlying altered risk at the 12q24 risk region. CONCLUSIONS:Our results demonstrate the power of combining genetics, computational genomics, and molecular studies to rationalize the identification of key variants and candidate target genes at breast cancer GWAS signals.
title: Thaumàzein | Rivista di Filosofia, Vol. 9 No. 2 (2021): Helmuth Plessner. Philosophy and Life
title: Helmuth Plessner. Philosophy and Life
titleType: AlternativeTitle
Creators: name: Thaumàzein | Rivista Di Filosofia
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2022

description: Helmuth Plessner’s thought is widely known in Italy, where today most of his work is translated and analysed by many experts, who underline the depth and novelty of his positions. This monographic issue dedicated to him gathers original contributions articulated along different paths, mainly focusing on Plessner’s effort to coordinate philosophical and scientific research on the nature of the human being in a multiform form.
description: Introduzione a "Filosofia e vita"...7-13 «Stufen des Organischen und der Mensch» (1928) und «Macht und menschliche Natur» (1931)...51-93 Staunen-Lernen angesichts der menschlichen Würde...170-192 Education in reality. ...14-50 Von der «verspäteten Nation» der Deutschen zur verspäteten Föderation Europas...111-133 Vida y distancia en «Límites de la comunidad»...134-150 Sport and performance ethics in Helmuth Plessner...229-246 Esperienza, intuizione, espressione. L’antropologia filosofica di Plessner tra filosofia della vita e logica ermeneutica...151-169 Una leggerezza originaria. Helmuth Plessner e il concetto di Spiel...209-228 Forme e figurazioni in Helmuth Plessner...193-208 Der eigene Tod und das menschliche Miteinander – gelingende Sterbebegleitung vor dem Hintergrund der philosophischen Anthropologie Helmuth Plessners...94-110
title: Extended Calibration of Flame Atomic-Absorption Instruments by a Flow Injection Peak Width Method
Creators: name: Tyson, Julian
Publisher: name: University of Massachusetts Amherst
Year: 1984
Subjects: subject: Atomic-absorption calibration
subject: flow injection analysis
subject: peak width
subject: Chemistry

description: The principles of two existing methods of calibration based on flow injection methodology are outlined and the mathematical basis of a method based on peak width is presented. On the basis of the single well stirred tank model, it is shown that peak width at any concentration is proportional to logarithm of a function of concentration. The relationship is verified experimentally over the range 1-1 000 p.p.m. of magnesium. The advantages and limitations of the method are discussed.
Spatiotemporal Variability of Benthic Communities on Weathervane Scallop Beds off Alaska
Creators: name: Glass, Jessica R.
name: Kruse, Gordon H.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Marine benthic communities are critical biotic components of habitat due to their roles in ecosystem function and health and as indicators of ecosystem change. Benthic communities are receiving increasing attention as institutions adopt ecosystem-oriented research approaches. We conducted a multidecadal analysis of benthic communities in areas targeted by a commercial weathervane scallop Patinopecten caurinus fishery on the continental shelf off Alaska. Using bycatch data collected by onboard observers during 1996–2012, we analyzed spatiotemporal patterns in community composition on weathervane scallop beds. We also explored whether spatiotemporal differences were related to environmental (sediment and depth) and anthropogenic (dredging effort) variables. Statistically significant (P < 0.05) temporal changes in community composition occurred during 1996–2012, with a split between 1996 and 1999 and subsequent years. Taxa contributing to temporal changes were not consistent across fishery registration areas. Significant spatial differences in community structure were detected both at the scale of registration areas (200–2,000 km) and individual scallop beds (<50 km). We also found significant correlations between benthic species composition and environmental and anthropogenic variables over space and time. Although the relationships were generally weak, the ecological associations were consistent with expected depth and sediment relationships in this region. Our results are directly relevant to the habitat objective of the scallop fishery management plan, inform essential fish habitat designations for weathervane scallops and other commercially important species, and serve as a baseline against which to compare future changes associated with fishing and climate change. Ensuing research should include the collection of environmental data at the spatial scale of individual scallop beds as well as controlled experiments on the impacts of fishing on benthic communities and their recovery. Received August 19, 2016; accepted August 8, 2017
Microstructural constraints on magmatic mushes under Kīlauea Volcano, Hawai'i.
Creators: name: Wieser, Penny E
name: Edmonds, Marie
name: Maclennan, John
name: Wheeler, John
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Distorted olivines of enigmatic origin are ubiquitous in erupted products from a wide range of volcanic systems (e.g., Hawai'i, Iceland, Andes). Investigation of these features at Kīlauea Volcano, Hawai'i, using an integrative crystallographic and chemical approach places quantitative constraints on mush pile thicknesses. Electron backscatter diffraction (EBSD) reveals that the microstructural features of distorted olivines, whose chemical composition is distinct from undistorted olivines, are remarkably similar to olivines within deformed mantle peridotites, but inconsistent with an origin from dendritic growth. This, alongside the spatial distribution of distorted grains and the absence of adcumulate textures, suggests that olivines were deformed within melt-rich mush piles accumulating within the summit reservoir. Quantitative analysis of subgrain geometry reveals that olivines experienced differential stresses of ∼3-12 MPa, consistent with their storage in mush piles with thicknesses of a few hundred metres. Overall, our microstructural analysis of erupted crystals provides novel insights into mush-rich magmatic systems.
Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization.
Creators: name: Zuber, Verena
name: Colijn, Johanna Maria
name: Klaver, Caroline
name: Burgess, Stephen
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Modern high-throughput experiments provide a rich resource to investigate causal determinants of disease risk. Mendelian randomization (MR) is the use of genetic variants as instrumental variables to infer the causal effect of a specific risk factor on an outcome. Multivariable MR is an extension of the standard MR framework to consider multiple potential risk factors in a single model. However, current implementations of multivariable MR use standard linear regression and hence perform poorly with many risk factors. Here, we propose a two-sample multivariable MR approach based on Bayesian model averaging (MR-BMA) that scales to high-throughput experiments. In a realistic simulation study, we show that MR-BMA can detect true causal risk factors even when the candidate risk factors are highly correlated. We illustrate MR-BMA by analysing publicly-available summarized data on metabolites to prioritise likely causal biomarkers for age-related macular degeneration.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Cart. 193 (11 H 78), f. 0257r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0257r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0257r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Additional file 4 of Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis
Creators: name: Mukai, Chinatsu
name: Choi, Eunju
name: Sams, Kelly L.
name: Klampen, Elena Zu
name: Anguish, Lynne
name: Marks, Brooke A.
name: Rice, Edward J.
name: Wang, Zhong
name: Choate, Lauren A.
name: Chou, Shao-Pei
name: Kato, Yukinari
name: Miller, Andrew D.
name: Danko, Charles G.
name: Coonrod, Scott A.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 4. FS2. ChRO-seq counts on PDPN and LAMA4 gene bodies.
Macroscopes for Playing with Scale
Creators: name: Börner, Katy
name: Record, Lisel
Publisher: name: figshare
Year: 2017
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Macroscopes are software tools that help you focus on patterns in data that are too large or complex to see with the naked eye. Interactive by nature, you can use them to ask and answer questions of the data.

Organized by the Cyberinfrastructure for Network Science Center at Indiana University, the Places & Spaces: Mapping Science exhibition showcases examples of science maps and macroscopes from around the globe and from diverse disciplines. Innovative and inspiring, these visualizations use data to tell science stories and illuminate promising new areas of research.