Comparative evaluation of enema alone and in combination with oral polyethylene glycol for bowel preparation before transvaginal pelvic floor reconstruction in elderly patients: a retrospective cohort study
Creators: name: Chu, Lei
name: Liang, Junhua
name: Wu, Siyu
name: Jin, Xia
name: Li, Huaifang
name: Tong, Xiaowen
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: The aim of this retrospective study was to assess the value of using an enema alone for mechanical bowel preparation (MBP) before transvaginal pelvic floor reconstruction (TPFR) in patients ≥65 years old. In total, 190 patients were included [81 in the enema group <i>vs.</i> 109 in the enema + polyethylene glycol (PEG) group]. The levels of serum potassium (<i>p</i> = .004) and calcium (<i>p</i> = .005) were higher in the enema group after surgery. The decrease in serum calcium was more significant in the enema + PEG group (<i>p</i> = .027). More patients in the enema + PEG group developed hypokalaemia (<i>p</i> = .035) or hypocalcaemia (<i>p</i> = .008) after surgery. The incidence of thrombus and surgical site infection was similar and earlier bowel movement was evident in the enema group (<i>p</i> = .000). Overall, the enema group used more laxatives (<i>p</i> = .026). Using enema alone before TPFR reduces the incidence of electrolyte disturbances with no increase in surgical complications in elderly patients.IMPACT STATEMENT<b>What is already known on this subject?</b> TPFR is an effective treatment for pelvic organ prolapse (POP) in elderly women. Bowel preparation performed before gynecological surgery can reduce surgical site infection, but increase discomfort and electrolyte disturbance.<b>What do the results of this study add?</b> The levels of serum potassium and calcium were lower in the enema + PEG group than in the enema group after surgery and more patients developed hypokalaemia or hypocalcaemia in the enema + PEG group. The incidence of thrombus and surgical site infection was similar between the two groups. Bowel movement was earlier in the enema group.<b>What are the implications of these findings for clinical practice and/or future research?</b> Using enema alone before TPFR reduces the incidence of electrolyte disturbance and does not increase surgical complications. This conclusion needs to be confirmed by random controlled trial studies in the future. <b>What is already known on this subject?</b> TPFR is an effective treatment for pelvic organ prolapse (POP) in elderly women. Bowel preparation performed before gynecological surgery can reduce surgical site infection, but increase discomfort and electrolyte disturbance. <b>What do the results of this study add?</b> The levels of serum potassium and calcium were lower in the enema + PEG group than in the enema group after surgery and more patients developed hypokalaemia or hypocalcaemia in the enema + PEG group. The incidence of thrombus and surgical site infection was similar between the two groups. Bowel movement was earlier in the enema group. <b>What are the implications of these findings for clinical practice and/or future research?</b> Using enema alone before TPFR reduces the incidence of electrolyte disturbance and does not increase surgical complications. This conclusion needs to be confirmed by random controlled trial studies in the future.