cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phenolic content and in vitro antifungal activity of unripe grape extracts from agro-industrial wastes
Creators: name: Simonetti, Giovanna
name: D’Auria, Felicia Diodata
name: Mulinacci, Nadia
name: Milella, Rosa Anna
name: Antonacci, Donato
name: Innocenti, Marzia
name: Pasqua, Gabriella
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: The antifungal activity of unripe grape extracts from agro-industrial wastes has been evaluated against several strains of Candida spp. and dermatophytes. All the extracts tested showed antifungal activity. The geometric mean MIC ranged from 53.58 to 214.31 μg/mL for Candida spp. and from 43.54 to 133.02 μg/mL for dermatophytes. The chemical analyses have been carried out using Liquid Chromatograph equipped with a DAD and MS detectors. Flavan-3-ols were the main metabolites within all samples ranged from 3.3 to 6.8 mg/g fresh weight. For Candida spp. highest negative significant correlation has been found between MICs and polymeric flavan-3-ols (r = −0.842; p r = −0.962; p
title: Characterization of statistical co-polymer vinylidene fluoride-hexafluoropropylene-phenylphosphonic acid functionalized hexafluoropropylene for potential applications as a proton electrolyte membrane
Creators: name: Smith, Steve
name: Motz, Andrew
name: Horan, Jim
name: Kuo, Mei-Chen
name: Herring, Andrew M.
Publisher: name: Mountain Scholar
Year: 2017

description: Meeting the world’s growing demand for energy without contributing to the emergent problem of anthropogenic climate change requires the use of renewable, carbon-free energy sources which in turn are contingent on advances in materials science. A newly synthesized statistical co-polymer of vinylidene fluoride, hexafluoropropylene and phenylphosphonic acid functionalized hexafluoropropylene (PolyPPA) shows potential for use as a polymer electrolyte membrane (PEM) in a variety of green-energy applications including proton pumps, flow batteries and high temperature-low relative humidity fuel cells. Preliminary testing of PolyPPA samples synthesized using a high molecular weight and low molecular weight feedstock show comparable conductivity, thermal stability and water uptake. Both high and low molecular weight PolyPPA exhibit minimal water uptake, are thermally stable to 160 °C, contain tightly bound water and exhibit low but measurable conductivity with best relative performance in high temperature and low relative humidity conditions. Despite a relatively low conductivity, the absence of liquid acid and the thermal stability suggests possible high temperature and high pressure applications. Future work needs to be conducted to determine how the degree of phenylphosphonic acid functionalization affects the conductivity and mechanical properties to determine an optimal formulation to minimize area specific resistance.
Генетик Василий Николаевич Слепков: документальные штрихи к портрету
Creators: name: А. И. Ермолаев
Publisher: name: Историко-биологические исследования
Year: 2019
Subjects: Слепков Василий Николаевич
история генетики
Институт красной профессуры
Казанский университет
репрессии
«Правый центр»
Бухарин Н.И.
Агол И.И.
Серебровский А.С.

description: Впервые публикуются несколько документов, связанных с деятельностью Василия Николаевича Слепкова (1902–1937). Он широко известен как участник философских дискуссий в генетике в 1920-е гг. и как соавтор первого российского исследования по индуцированному мутагенезу у дрозофилы (Серебровский и др., 1928). Первые семь из публикуемых документов относятся к периоду учёбы в Институте красной профессуры, т. е. годам становления Слепкова как генетика. Это заявление в ИКП (1925), автобиография (1925), отзыв Б.М. Завадовского о работе И.И. Агола и В.Н. Слепкова (1926), отзыв А.С. Серебровского (1928), отчёт В.Н. Слепкова о работе в лаборатории Серебровского (1928) и два заявления с просьбой о командировке в Германию (1928). Остальные документы относятся к казанскому периоду деятельности В.Н. Слепкова, он работал сначала в Татарском коммунистическом университете (ТКУ) (1929–1930 гг.), а потом — в Казанском государственном университете (КГУ) (1930–1932 гг.). В начале 1933 г. его арестовали и приговорили к трём годам тюремного заключения якобы как «участника антипартийной организации правых». В 1937 г. он был арестован вторично по тому же обвинению и расстрелян. Публикуются: выписка из приказа по КГУ о зачислении Слепкова на работу (1931), страница из «Предметной книжки» студента Л. Ценципера (1931), два протокола заседаний бюро ВКП(б) Зоологического отделения КГУ (1933), протокол допроса в НКВД (1937), свидетельство о смерти и справка о реабилитации (1958).
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 181 (11 H 754), 165 folios, f. 0014
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2017
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0014, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0014, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Teacher referrals to speech pathologists for speech, language and communication needs in the first year of school
Creators: name: Beasley, Cassandra
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Children with speech, language and communication needs (SLCN) experience difficulties in many areas of their development and learning. Teachers are responsible for referring these children to speech-language pathologists (SLPs). Yet, teachers lack adequate knowledge, training or tools to accurately identify children with SLCN. Consequently, many children do not receive the speech therapy they need. A better understanding of teachers' and SLPs' views on the referral process and on suitable SLCN indicators might inform and enhance collaboration between the two professions, and ultimately help them provide better support for children with SLCN. This study examined the referral process for children with SLCN in the first year of school in New South Wales, Australia, and the importance that teachers and SLPs assign to indicators of SLCN. Two surveys were completed by 47 teachers and 56 SLPs. Semistructured interviews were conducted with 13 of these survey respondents, 6 teachers and 7 SLPs. The analysis of the data revealed: some confusion about the referral process among SLPs; teachers' hesitation in referring children with SLCN to SLPs and uncertainty about the scope of SLP practice; suggestions for improving children's level and ease of access to SLP services such as having more SLPs at schools, making SLP services more affordable, more professional development for teachers regarding SLCN; increasing parent involvement; and divergence in the importance that teachers and SLPs assign to indicators of SLCN in children.
O'ZBEK SHOIRASI NODIRABEGIM
Creators: name: Esonov, Z. Yu.
name: Ma'murova, S.
Publisher: name: Zenodo
Year: 2024

description: Mazkur maqolada, XIX asrda Qo’qon xonligi madaniy muhitining shakllanishi va taraqqiyotida muhim o’rin tutgan o’zbek shoirasi, ma’rifatparvari  Nodirabegimning hayoti va ijodi tarixi yoritilgan. Ma’lumotlar asosida uni yetishtirgan muhit, ijod yo’li va davlat hayotidagi o’rni masalalari tahlil etilgan.
Quantum Valley Hall Effect and Perfect Valley Filter Based on Photonic Analogs of Transitional Metal Dichalcogenides
Creators: name: Bleu, O.
name: Solnyshkov, D. D.
name: Malpuech, G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We consider theoretically staggered honeycomb lattices for photons which can be viewed as photonic analogs of transitional metal dichalcogenides (TMD) monolayers. We propose a simple realization of a photonic Quantum Valley Hall effect (QVHE) at the interface between two TMD analogs with opposite staggering on each side. This results in the formation of valley-polarized propagating modes whose existence relies on the difference between the valley Chern numbers, which is a $\mathbb{Z}_2$ topological invariant. We show that the magnitude of the photonic spin-orbit coupling based on the energy splitting between TE and TM photonic modes allows to control the number and propagation direction of these interface modes. Finally, we consider the interface between a staggered and a regular honeycomb lattice subject to a non-zero Zeeman field, therefore showing Quantum Anomalous Hall Effect (QAHE). In such a case, the topologically protected one-way modes of the QAHE become valley-polarized and the system behaves as a perfect valley filter.
title: ИССЛЕДОВАНИЕ ФИНАНСОВО-ЭКОНОМИЧЕСКОГО СОСТОЯНИЯ ПРЕДПРИЯТИЙ IT-ОТРАСЛИ НА ОСНОВЕ АНАЛИЗА ИНТЕРНЕТ-ДАННЫХ
title: Статья
titleType: Subtitle
Creators: name: Горбунов, С.Н.
name: Усатый, Р.С.
name: Саплев, М.В.
Publisher: name: "Южный Университет (ИУБиП)"
Year: 2020
Subjects: АНАЛИЗ ДАННЫХ
ОТКРЫТЫЕ ИНТЕРНЕТ-ИСТОЧНИКИ
ФИНАНСОВО-ЭКОНОМИЧЕСКОЕ СОСТОЯНИЕ

Abstract
Развитие представлений о теории мочеобразования (XVII–XX века)
Creators: name: А. С. Панова
name: Р. И. Айзман
name: М. А. Суботялов
Publisher: name: Историко-биологические исследования
Year: 2019
Subjects: история физиологии
физиология почек и водно-солевого обмена
мальпигиевы тельца
капсула Шумлянского-Боумена
теория мочеобразования
клиренс
осморецепция.

description: В статье представлены предпосылки становления современной физиологии почек и водно-солевого обмена. Актуальность настоящей статьи обусловлена необходимостью обобщения и дополнения фрагментарных исследований о процессе становления и развития почечной физиологии в историконаучном аспекте, что позволит выявить ключевые этапы в формировании целостного представления о процессах мочеобразования. В связи с этим целью данного обзора является анализ основных достижений в области физиологии почек и водно-солевого обмена, начиная с открытия в XVII веке беллиниевых протоков и мальпигиевых телец и заканчивая исследованиями середины XX столетия. Авторами представлено развитие двух конкурирующих гипотез мочеобразования: виталистической концепции У. Боумена, в которой основополагающая роль в процессе образования мочи отводится «жизненной силе», и в противовес ей — антивиталистической механистической теории мочеобразования К. Людвига, целиком сводимой к физическим процессам. Борясь с двумя конкурирующими гипотезами своего времени, в начале XX века А. Кэшни, подытожив всю доступную на тот момент литературу о функции почек, сформулировал «современную теорию» образования мочи. Окончательно уладить спор 80-летней давности позволили эксперименты А. Ричардса и Д. Вирна. Благодаря последующим исследованиям, проведенным независимо Д. Ван Слайком, Г. Смитом и Л.А. Орбели, на смену представлениям о роли почки только как органа экскреции пришло понимание её значения для обеспечения постоянства внутренней среды организма. Таким образом, к середине XX века было сформировано целостное представление о механизме мочеобразования.
Борьба с гриппом в середине XIX в. в Казанской губернии
Creators: name: М. В. Трушин
Publisher: name: Историко-биологические исследования
Year: 2019
Subjects: грипп
Казанская губерния
Казанский университет
профилактика
лечение

description: Грипп является актуальной проблемой человечества на протяжении тысячелетий. В Российской империи регулярные описания вспышек гриппа начинают встречаться с конца XVIII в. Уже в начале следующего столетия он рассматривался как самостоятельное заболевание. Данная работа посвящена описанию вспышек гриппа в Казанской губернии в середине XIX в. Представлены данные архивных документов с описанием патологических изменений, вызванных гриппом, а также ряд профилактических мер. Проводится обсуждение эффективности противогриппозных мероприятий, рекомендованных казанскими лекарями.
Rethinking the binary: how Dungeons and dragons complicates the player/game relationship
Creators: name: Spence, Jeremy Alexander Hall
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This thesis will explore how tabletop role-playing games use a three-part game system in order to construct player experience, and how such a system complicates the traditionally very clear divide between player and game that much of the current game studies' literature suggests. To do so, it will look at how the three main units of the Dungeons and Dragons game system: the rules, the dungeon master, and the players, each function independently to shape the game experience, but also how each unit of the system limits the control that the other two units possess over the game. The thesis will primarily be drawing upon literature from the field of game studies, both concerning video games and tabletop role-playing games, but will also employ theorists from broader disciplines. It will utilize the anthropological works of Victor Turner in order to understand tabletop role-playing games as a social ritual, possible worlds theory,as described by Marie-Laurie Ryan, to discuss the multiple fictional worlds that exist simultaneously within games such as Dungeons and Dragons, and Michel de Certeau's views on power, in order to analyse the power relations between the three units of the game system.
Magnetic excitations in the normal and nematic phases of iron pnictides
Creators: name: Zhang, Hai-Yang
name: Xu, Ning
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In this paper, we study theoretically the behaviors of the magnetic excitations(MEs) in the normal and nematic phases of iron pnictides. The normal state MEs exhibit commensurability to diamond and to square-like structure transition with the increase of energy. This structure transition persists in the spin and orbital scenarios of nematic phases, although the MEs show anisotropic behaviors due to the C4 symmetry breaking induced by the nematic orders. The MEs exhibit distinct energy evolution behaviors between the spin and orbital scenarios of nematicity. For the spinnematic scenario, the anisotropy of the MEs persists up to the high energy region. In contrast, for the orbital-nematic scenario, it reduces dramatically in the low energy region and is negligible in the high energy region. These distinct behaviors of the MEs are attributed to the different origins between the spin and orbital scenarios of nematic orders.
description: 13 pages, 6 figures
Научный путь Евгении Николаевны Ивановой (к 130-летию со дня рождения)
Creators: name: А. В. Собисевич
name: Н. Г. Лисевич
Publisher: name: Историко-биологические исследования
Year: 2019
Subjects: почвоведение
классификация почв
география почв.

description: Е.Н. Иванова стала одним из знаковых учёных-почвоведов XX в. Начало её деятельности связано с участием экспедициях под руководством географа и почвоведа С.С. Неуструева в Оренбургской губернии. Позднее она самостоятельно руководила экспедиционными исследованиями, в которых принимали ставшие впоследствии известными такие почвоведы, как И.П. Герасимов, Е.В. Лобова, Н.Н. Розов. Работала в Почвенном отделении КЕПС. Пройдя практику в лаборатории специалиста в области химии почв К.К. Гедройца, Е.Н. Иванова смогла выработать оригинальные лабораторно-экспериментальные методы изучения почв. Её исследования позволили внести значимый вклад в развитие географии почв Советского Союза.
A Necessary and Suffcient Condition for Uniqueness of the Trivial Solution in Semilinear Parabolic Equations
Creators: name: Laister, R.
name: Robinson, J. C.
name: Sierzega, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In their 1968 paper Fujita and Watanabe considered the issue of uniqueness of the trivial solution of semilinear parabolic equations with respect to the class of bounded, non-negative solutions. In particular they showed that if the underlying ODE has non-unique solutions (as characterised via an Osgood-type condition) {\em and} the nonlinearity $f$ satisfies a concavity condition, then the parabolic PDE also inherits the non-uniqueness property. This concavity assumption has remained in place either implicitly or explicitly in all subsequent work in the literature relating to this and other, similar, non-uniqueness phenomena in parabolic equations. In this paper we provide an elementary proof of non-uniqueness for the PDE without any such concavity assumption on $f$. An important consequence of our result is that uniqueness of the trivial solution of the PDE is equivalent to uniqueness of the trivial solution of the corresponding ODE, which in turn is known to be equivalent to an Osgood-type integral condition on $f$.
Gamma-ray line constraints on Coy Dark Matter
Creators: name: Hektor, Andi
name: Marzola, Luca
name: Tuvi, Taavi
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Coy dark matter is an effective scheme in which a fermionic dark matter candidate interacts with the Standard Model fermions via a pseudoscalar mediator. This simple setup avoids the strong constraints posed by direct detection experiments in a natural way and explains, on top of the observed dark matter relic abundance, the spatially extended gamma-ray excess recently detected at the Galactic Center. In this Letter we study the phenomenology of coy dark matter accounting for a novel signature of the model: the diphoton annihilation signal induced by the Standard Model fermions at the loop level. By challenging the model with the observations of spheroidal dwarf satellite galaxies and the results of gamma-ray line searches obtained by the Fermi LAT experiment, we assess its compatibility with the measured dark matter relic abundance and the Galactic Center excesses. We show that despite the gamma-ray line constraint rules out a significant fraction of the considered parameter space, the region connected to the observed Galactic Center excess remains currently viable. Nevertheless, we find that next-generation experiments such as DAMPE, HERD and GAMMA-400 have the potential to probe exhaustively this elusive scenario.
description: 9 pages, 3 figures; references and a footnote added; a latex error corrected
Emotion and gesture effects on narrative comprehension: do gestures moderate emotion enhanced memory?
Creators: name: Guilbert, Daniel
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Research in the field of emotion suggests that emotionally negative stories are more memorable than positive or neutral stories (e.g., Van Bergen, Wall, & Salmon, 2015). Similarly, research has found that people remember stories more effectively when the narrator provides relevant hand gestures to accompany story content (Hostetter, 2011). Given the relative difficulty associated with remembering positive or neutral stories, this study explores whether gestures can be used to compensate for this recall deficit, by testing gesture effects for negative, neutral,and positive stories. In Experiment 1, fifty children aged 4-6 years viewed a video containing two negative, two positive, and two neutral stories. Gesture condition was manipulated between groups, such that participants watched a video in which the narrator provided: (i) gestures reflecting the main emotion of each story; (ii) gestures reflecting the main event of each story; or (iii) no gestures. Children recalled negative emotions more effectively than positive or neutral emotions. Compared to children who viewed no gestures, children who viewed emotion gestures or event gestures recalled more narrative content. Crucially, the memorial benefits of gesture remained consistent across emotional valence conditions. To examine the developmental aspects of these phenomena, seventy-four adults were tested in Experiment 2, using the same stimuli as Experiment 1. Adults recalled events more effectively from negative stories rather than positive or neutral stories. Compared to adults who viewed no gestures, those who viewed emotion gestures did not recall more narrative content, while those who viewed event gestures recalled significantly less narrative content. Again, these findings were consistent across emotional valence conditions. Overall, the results of this study suggest that the extent to which viewing relevant gestures can facilitate narrative comprehension depends less on the emotional valence of the narratives, and more on the difficulty of the task, and the age and cognitive ability of viewers. This research has important implications when deciding how and when to use gestures to best facilitate listeners’ narrative comprehension.
Additional file 1 of Norepinephrine protects against cochlear outer hair cell damage and noise-induced hearing loss via α2A-adrenergic receptor
Creators: name: Tian, Chaoyong
name: Yang, Yang
name: Wang, Renfeng
name: Li, Yao
name: Sun, Fei
name: Chen, Jun
name: Zha, Dingjun
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
Wind Shear and Turbulence on Titan : Huygens Analysis
Creators: name: Lorenz, Ralph
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Wind shear measured by Doppler tracking of the Huygens probe is evaluated, and found to be within the range anticipated by pre-flight assessments (namely less than two times the Brunt-Vaisala frequency). The strongest large-scale shear encountered was ~5 m/s/km, a level associated with 'Light' turbulence in terrestrial aviation. Near-surface winds (below 4km) have small-scale fluctuations of ~0.2 m/s , indicated both by probe tilt and Doppler tracking, and the characteristics of the fluctuation, of interest for future missions to Titan, can be reproduced with a simple autoregressive (AR(1)) model. The turbulent dissipation rate at an altitude of ~500m is found to be 16 cm2/sec3, which may be a useful benchmark for atmospheric circulation models.
description: 19 Pages, 7 figures. Submitted to Icarus
New semicarbazones as gorge-spanning ligands of acetylcholinesterase and potential new drugs against Alzheimer’s disease: Synthesis, molecular modeling, NMR, and biological evaluation
Creators: name: Neto, Denise Cristian Ferreira
name: Lima, Josélia Alencar
name: Almeida, Joyce Sobreiro Francisco Diz De
name: Tanos Celmar Costa França
name: Nascimento, Claudia Jorge Do
name: Villar, José Daniel Figueroa
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Two new compounds (E)-2-(5,7-dibromo-3,3-dimethyl-3,4-dihydroacridin-1(2H)-ylidene)hydrazinecarbothiomide (3) and (E)-2-(5,7-dibromo-3,3-dimethyl-3,4-dhihydroacridin-1(2H)-ylidene)hydrazinecarboxamide (4) were synthesized and evaluated for their anticholinesterase activities. In vitro tests performed by NMR and Ellman’s tests, pointed to a mixed kinetic mechanism for the inhibition of acetylcholinesterase (AChE). This result was corroborated through further docking and molecular dynamics studies, suggesting that the new compounds can work as gorge-spanning ligands by interacting with two different binding sites inside AChE. Also, in silico toxicity evaluation suggested that these new compounds can be less toxic than tacrine.
The Effect of Transient Accretion on the Spin-Up of Millisecond Pulsars
Creators: name: Bhattacharyya, Sudip
name: Chakrabarty, Deepto
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: A millisecond pulsar is a neutron star that has been substantially spun up by accretion from a binary companion. A previously unrecognized factor governing the spin evolution of such pulsars is the crucial effect of non-steady or transient accretion. We numerically compute the evolution of accreting neutron stars through a series of outburst and quiescent phases considering the drastic variation of the accretion rate and the standard disk-magnetosphere interaction. We find that, for the same long-term average accretion rate, X-ray transients can spin up pulsars to rates several times higher than can persistent accretors, even when the spin down due to electromagnetic radiation during quiescence is included. We also compute an analytical expression for the equilibrium spin frequency in transients, by taking spin equilibrium to mean that no net angular momentum is transferred to the neutron star in each outburst cycle. We find that the equilibrium spin rate for transients, which depends on the peak accretion rate during outbursts, can be much higher than that for persistent sources. This explains our numerical finding. This finding implies that any meaningful study of neutron star spin and magnetic field distributions requires the inclusion of the transient accretion effect, since most accreting neutron star sources are transients. Our finding also implies the existence of a submillisecond pulsar population, which is not observed. This may point to the need for a competing spin-down mechanism for the fastest-rotating accreting pulsars, such as gravitational radiation.
description: 13 pages, 6 figures, accepted for publication in The Astrophysical Journal
300 лет первой научной экспедиции в Сибирь: Даниэль Готлиб Мессершмидт и изучение его научного наследия
Creators: name: Е. Ю. Басаргина
name: Л. Д. Бондарь
name: И. В. Тункина
Publisher: name: Историко-биологические исследования
Year: 2019
Subjects: Даниэль Готлиб Мессершмидт
академические экспедиции XVIII в.
исследование Сибири в XVIII в.
немецкие учёные на российской службе/

description: 6 марта 2019г. в Малом конференц-зале Санкт-Петербургского научного центра Российской академии наук (СПбНЦ РАН) состоялось открытое заседание Учёного совета СанктПетербургского филиала Архива Российской академии наук и Объединённого научного совета по общественным и гуманитарным наукам СПбНЦ РАН в формате научных чтений «К 300-летию начала экспедиции Даниэля Готлиба Мессершмидта в Сибирь (1719–1727)». Чтения стали центральным пунктом в ряде юбилейных мероприятий, посвящённых изучению научного наследия немецкого учёного-энциклопедиста, ставшего первым исследователем Сибири с позиций европейской науки. Это заседание, как и ряд других издательских проектов и научных сессий 2019 г., объединило ведущих академических и университетских мессершмидтологов Санкт-Петербурга, а также немецких коллег. Академики В. Лефельдт (Гёттинген), Н.Н. Казанский и петербургские исследователи Д.Г. Савинов, И.В. Тункина, Е.Ю. Басаргина, А.К. Сытин, Л.Д. Бондарь, С.И. Зенкевич, А.В. Зорин, А.В. Смирнов, Ю.А. Дунаева осветили большую часть научной биографии Д.Г. Мессершмидта: его приглашение на российскую службу, первый год пребывания в Сибири (в Тобольске) и ведение им врачебной практики, его разноплановую экспедиционную деятельность, проявившуюся в изучении зоологических, ботанических, археологических, этнографических объектов, языков сибирских и восточных народов, в картографических и метеорологических исследованиях, а также его художественное творчество, нашедшее проявление в рисовании и поэзии. По материалам выступлений на чтениях собран тематический сборник. Исследовательская работа международной команды мессершмидтологов находит свою реализацию в виде издательских проектов и в докладах на научных сессиях в России и за рубежом, посвящённых самоотверженному участию врача и ботаника из Данцига в научном освоении просторов Российской империи.
title: ADCO, Cart. 186 (11 H 71), f. 0236v
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la Côte-d'Or, C
art. 186 (11 H 71). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la
 Côte-d'Or, Cart. 186 (11 H 71), f. 0236v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-
project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Nutraceutical properties of whole dried sugarcane extracts studied by proteomics
Creators: name: Noble, Daniel Bucio
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Many chronic diseases are associated with the activation of inflammatory mediators. This can lead to excessive release of pro-inflammatory cytokines and the generation of reactive oxygen species (ROS). Some nutraceuticals are rich in polyphenols providing strong antioxidant attributes which have been reported to counteract some of the deleterious effects of ROS. However, cellular mechanisms underlying nutraceutical therapeutic properties are often not well elucidated. In this thesis, the anti-inflammatory properties of the nutraceutical, whole dried sugarcane (WDS), was investigated using proteomic techniques. Chemical assays of WDS ethanol extracts (WDS EE) showed the presence of polyphenols and flavonoids conferring potent antioxidant activity. In lipopolysaccharide (LPS)-stimulated SW480 colon cancer cells, WDS EE reversed the phosphorylation of NFκB and inhibited the secretion of IL-8 in a mechanism shown to be dependent of C-Raf and AKT phosphorylation. Mass spectrometry (MS)-based proteomics using label-free SWATH-MS demonstrated WDS EE to alter the expression of oxidative stress mediators FOXRED1 and the selenoprotein SELH, amongst others. Based on protein expression, prediction analysis proposed the down-regulation of NFκB pathway members TLR2, TLR4, NIK and IκB. In the same model, phosphoproteomics studies indicated that WDS EE interferes in the phosphorylation of cell stress regulator proteins c-Jun, EGFR, PKA, PKCβ and SIRT1, interpreted as regulating anti-inflammatory related signalling mechanisms. As a feed supplement to mice on high-fat diet (HFD), WDS was shown to reduce the plasma concentration of the circulating markers of inflammation IL-1β and GM-CSF. The proteomic analysis of liver tissue from WDS-feed, HFD mice showed changes to STAT3 and the selenium associated proteins SEP15 and SecS. Prediction analysis based on protein expression indicated the down-regulation of inflammatory-related hepatic functions. Taken xvitogether, this thesis has revealed some of the mechanisms associated with the anti-inflammatory properties of WDS extracts in in vitroand in vivomodels.
ГЕОЛОГИЧЕСКАЯ ИЗУЧЕННОСТЬ УГОЛЬНЫХ МЕСТОРОЖДЕНИЙ КАК ФАКТОР ПОВЫШЕНИЯ ПРОМЫШЛЕННОЙ БЕЗОПАСНОСТИ
Creators: name: Писаренко Марина Владимировна
Publisher: name: Вектор ГеоНаук
Year: 2019
Subjects: угольные месторождения
геологическая изученность
многовариантная геометризация
геотехнологические решения
обрушение пород кровли.

description: при разработке горных проектов учет геологической изученности объекта освоения (неполных знаний о недрах) позволит повысить эффективность и безопасность принимаемых решений. Реализовать такой подход предлагается на основе многовариантной геометризации, порождает которую объективная неопределенность геологических званий об объекте освоения. Наличие многовариантных прогнозных карт потенциального состояния боковых пород, что показано на примерах реальных горных объектов, позволяет на стадии проектирования предусмотреть превентивные решения, направленные на повышение эффективности и безопасности ведения горных работ с учетом неполных знаний о недрах.
О ПОТЕНЦИАЛЕ ИСПОЛЬЗОВАНИЯ АЛЬТЕРНАТИВНЫХ ИСТОЧНИКОВ ЭНЕРГИИ В ФОРМИРОВАНИИ ЭНЕРГОЭФФЕКТИВНОСТИ ЗДАНИЙ
Creators: name: Черныш Надежда Дмитриевна
name: Сидякина Анастасия Юрьевна
Publisher: name: Вектор ГеоНаук
Year: 2019
Subjects: возобновляемые источники энергии
альтернативная энергетика
энергосбережение
энергоэффективность зданий

description: в статье приведены сведения о направлениях развития современной энергетики на основе использования возобновляемых энергетических источников. Это вызвано постепенным уменьшением природных ресурсов, ростом цен на них. Рассмотрены источники альтернативной энергии, используемые в России и Белгородской области, отражены преимущества и недостатки при их использовании. Выявлен потенциал и уровень использования альтернативных источников энергии в Белгородской области, их влияние на энергоэффективность объектов.
Perfect Elimination Orderings for Symmetric Matrices
Creators: name: Laurent, Monique
name: Tanigawa, Shin-ichi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: We introduce a new class of structured symmetric matrices by extending the notion of perfect elimination ordering from graphs to weighted graphs or matrices. This offers a common framework capturing common vertex elimination orderings of monotone families of chordal graphs, Robinsonian matrices and ultrametrics. We give a structural characterization for matrices that admit perfect elimination orderings in terms of forbidden substructures generalizing chordless cycles in graphs.
description: 16 pages, 3 figures
Using a best-worst scaling choice experiment to investigate sport sponsorship's impact on fans' purchase intentions
Creators: name: Almaiman, Khaled Hamad
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Purpose: Increasing customers' purchase intention levels is one of the main reasons companies engage in sport sponsorship deals. Previous studies in the sport sponsorship context have utilised rating scales to measure fans' purchase intentions. However, this approach has some serious limitations, such as acquiescence bias and hypothetical bias. To overcome the limitations associated with rating scales, this small-scale research uses a best-worst scaling method to experimentally investigate sponsorship's effects on fans' purchase intentions. Design/methodology approach: This research follows a quantitative approach applying best-worst scaling as the main method of research, enhanced by employing several well-known sport sponsorship constructs. The sample of this research consists of fans of two Australian soccer teams. Findings: The results of this study did not find any evidence of the effects of sport sponsorship on fans' purchase intentions from their favourite team's sponsors. Fans are more likely to consider buying the brand and the product they like without considering any sponsorship deal. Research limitations/implications: This study has three limitations related to the BWS design, the context of the research, and the level of sponsorship. However, this research provides a methodological implication by applying best minus worst method in BWS case 3 at attributes' level. Originality/value: This research is the first study to employ a best-worst scaling method in investigating the effects of sport sponsorship on fans' purchase intentions.
Carnet nº 18, commencé à Canton (p. 1)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 1-1-1931
Personality Functioning, Narcissism and Borderline Traits in the General Population Predict Deviations from the Optimal Time Perspective
Creators: name: Dussault, Olivier
name: Grondin, Simon
name: Laverdière, Olivier
Publisher: name: Brill Online
Year: 2024
Subjects: classificationCode: 520406
subject: Sensory processes, perception and performance

description: The aim of this article is to clarify and describe the relationships between levels of personality functioning, pathological personality traits from the borderline and narcissistic functioning, and time perspective (TP). The study was conducted online, and 210 participants completed eight questionnaires: Inventory of Personality Organization, Boredom Proneness Scale, Rejection Sensitivity Questionnaire, Barratt Impulsiveness Scale, Hypersensitive Narcissism Scale, Narcissistic Admiration and Rivalry Questionnaire, Depressive Experience Questionnaire, and Zimbardo Time Perspective Inventory. The results reveal that the pathological personality functioning was consistently associated with a deviation on each dimension of TP and the Deviation from the Balanced Time Perspective (DBTP) while the higher functioning personality indicator was associated with a balanced time perspective. When accounting for all traits in the regression, pathological personality traits predicted variance of Past-Negative, Present-Hedonistic, Present-Fatalistic, and the DBTP. Borderline and narcissistic traits were associated with the DBTP but demonstrated different time perspective profiles. Borderline traits showed an overall negative TP with a tendency to seek quick and intense pleasure in the present with no regards toward the future. These results show that there can be TP profile differences between borderline personalities, depending on their specific trait profile. Impulsivity plays an important role in how borderline personalities cope with their negative temporalities. Vulnerable narcissism is characterized by a negative past with the ability to recruit the future, while grandiose narcissism denotes an overall more balanced time perspective than their vulnerable counterpart.
Computational screening of fatty acid synthase inhibitors against thioesterase domain
Creators: name: Wanwisa Panman
name: Bodee Nutho
name: Supakarn Chamni
name: Supaporn Dokmaisrijan
name: Nawee Kungwan
name: Thanyada Rungrotmongkol
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Thioesterase (TE) domain of fatty acid synthase (FAS) is an attractive therapeutic target for design and development of anticancer drugs. In this present work, we search for the potential FAS inhibitors of TE domain from the ZINC database based on similarity search using three natural compounds as templates, including flavonoids, terpenoids, and phenylpropanoids. Molecular docking was used to predict the interaction energy of each screened ligand compared to the reference compound, which is methyl γ-linolenylfluorophosphonate (MGLFP). Based on this computational technique, rosmarinic acid and its eight analogs were observed as a new series of potential FAS inhibitors, which showed a stronger binding affinity than MGLFP. Afterward, nine docked complexes were studied by molecular dynamics simulations for investigating protein–ligand interactions and binding free energies using MM-PB(GB)SA, MM-3DRISM-KH, and QM/MM-GBSA methods. The binding free energy calculation indicated that the ZINC85948835 (R34) displayed the strongest binding efficiency against the TE domain of FAS. There are eight residues (S2308, I2250, E2251, Y2347, Y2351, F2370, L2427, and E2431) mainly contributed for the R34 binding. Moreover, R34 could directly form hydrogen bonds with S2308, which is one of the catalytic triad of TE domain. Therefore, our finding suggested that R34 could be a potential candidate as a novel FAS-TE inhibitor for further drug design.
Three-body decay of linear-chain states in $^{14}$C
Creators: name: Baba, Tomoyuki
name: Kimura, Masaaki
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The decay properties of the linear-chain states in $^{14}$C are investigated by using the antisymmetrized molecular dynamics. The calculation predicts two rotational bands with linear-chain configurations having the $π$-bond and $σ$-bond valence neutrons. For the $π$-bond linear-chain, the calculated excitation energies and the widths of $α$-decay to the ground state of $^{10}{\rm Be}$ reasonably agree with the experimental candidates observed by the $α+{}^{10}{\rm Be}$ resonant scattering. On the other hand, the $σ$-bond linear-chain is the candidate of the higher-lying resonant states reported by the break-up reaction. As the evidence of the $σ$-bond linear-chain, we discuss its decay pattern. It is found that the $σ$-bond linear-chain not only decays to the excited band of $^{10}{\rm Be}$ but also decays to the three-body channel of $^{6}{\rm He}+α+α$, and the branching ratio of these decays are comparable. Hence, we suggest that this characteristic decay pattern is a strong signature of the linear-chain formation and a key observable to distinguish two different linear-chains.
Molecular dynamics of a far positioned SOD1 mutant V14M reveals pathogenic misfolding behavior
Creators: name: Dharma Rao Tompa
name: Saraboji Kadhirvel
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Human superoxide dismutase (Cu/Zn SOD1) is a homodimeric enzyme. Mutations in Cu/Zn SOD1 causes a familial form of amyotrophic lateral sclerosis (fALS), and aggregation of mutant SOD1 has been proposed to play a role in neurodegeneration. Though a majority of the mutations are point substitutions, there are a few changes that result in amino acid deletions or truncations of the polypeptide. These pathogenic mutations are scattered throughout the three-dimensional structure of the dimeric enzyme, which creates a puzzling pattern to investigate the molecular determinants of fALS. The most common hypothesis proposed that the misfolding of SOD1 mutants are primarily triggered by decreased affinity for metal ions. However, this hypothesis is challenging, as a significant number of disease-causing mutations are located far away from the metal-binding site and dimer interface. So in the present study, we have investigated the influence of such a far positioned pathogenic mutation, V14M, in altering the stability and folding of the Cu/Zn SOD1. Though the location of Val14 is far positioned, it has a vital role in the stability of SOD1 by preserving its hydrophobic cluster at one end of the β barrel domain. We have performed MD simulations of the V14M mutant for 80 ns timescale. The results reveal the fact that irrespective of its location, V14M mutation triggers a conformational change that is more similar to that of the metal-deficient holo form and could resemble an intermediate state in the folding reaction which results in protein misfolding and aggregation.
Super- and Anti-Principal Modes in Multi-Mode Waveguides
Creators: name: Ambichl, Philipp
name: Xiong, Wen
name: Bromberg, Yaron
name: Redding, Brandon
name: Cao, Hui
name: Rotter, Stefan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We introduce a new type of states for light in multimode waveguides featuring strongly enhanced or reduced spectral correlations. Based on the experimentally measured multi-spectral transmission matrix of a multimode fiber, we generate a set of states that outperform the established "principal modes" in terms of the spectral stability of their output spatial field profiles. Inverting this concept also allows us to create states with a minimal spectral correlation width, whose output profiles are considerably more sensitive to a frequency change than typical input wavefronts. The resulting "super-" and "anti-principal" modes are made orthogonal to each other even in the presence of mode-dependent loss. By decomposing them in the principal mode basis, we show that the super-principal modes are formed via interference of principal modes with closeby delay times, whereas the anti-principal modes are a superposition of principal modes with the most different delay times available in the fiber. Such novel states are expected to have broad applications in fiber communication, imaging, and spectroscopy.
description: 8 pages, 5 figures, plus supplementary material