cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Endophytic colonization and nitrogen fixation by Paenibacillus polymyxa in association with lodgepole pine and western redcedar
Creators: name: Anand, Richa
Publisher: name: University of British Columbia
Year: 2010

description: In this study I provide evidence of biological nitrogen fixation by endophytic, diazotrophic bacteria as a possible source of nitrogen for lodgepole pine (Pinus contorta var. latifolia (Dougl. Engelm.) and western redcedar (Thuja plicata Donn.); conifers that are known for their ability to grow in nitrogen-poor forests of western North America. Diazotrophic bacteria were isolated from root, stem and needle tissues of both tree species, growing on forested sites with contrasting N availability in the interior of British Columbia, Canada. Members of the genera Bacillus and Paenibacillus dominated the culturable, endophytic bacterial community in tissues of both tree species. A Paenibacillus polymyxa isolate strain P2b-2R from lodgepole pine at the nitrogen deficient site near Williams Lake, B.C., demonstrated high (5.1705 μmols C₂H₄/ml), replicable, nitrogenase activity, under laboratory conditions. P. polymyxa strain P2b-2R inoculated and control lodgepole pine and cedar seedlings were grown in a sand – turface mixture enriched with a 5 atom % excess ¹⁵N [Ca(¹⁵NO₃)₂] solution. Root, shoot and seedling length, fresh weight and dry weight demonstrated that both tree species accumulated significantly higher biomass when inoculated with strain P2b-2R. ¹⁵N atom % excess indicated that P2b-2R inoculated lodgepole pine and western redcedar derived 67.53 and 21.94% of their total foliar nitrogen from the atmosphere, respectively. Using in situ confocal laser scanning microscopy, cells of strain P2b-2R tagged with green fluorescent protein were found to colonize the root and stem cortical cells of lodgepole pine, both inter- and intracellularly. Sequences of nif B, H and D genes of strain P2b-2R were obtained using PCR. Phylogenies based on nifH and nifD genes of strain P2b-2R place these genes in monophyletic groups with those of free-living cyanobacteria and root nodule-forming Frankia, respectively. Within the genus Paenibacillus, based on nifH and nifD phylogenies, P. polymyxa was most closely related to P. massiliensis T7, a bacterium isolated from the rhizosphere of willow trees (Salix spp.) in Beijing. These results provide the first evidence of significant endophytic nitrogen fixation in conifer species growing under nitrogen-limited conditions and support the possibility of a novel, ecologically significant interaction between coniferous trees and diazotrophic bacteria.
Correlated and zonal errors of global astrometric missions: a spherical harmonic solution
Creators: name: Makarov, V. V.
name: Dorland, B. N.
name: Gaume, R. A.
name: Hennessy, G. S.
name: Berghea, C. T.
name: Dudik, R. P.
name: Schmitt, H. R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We propose a computer-efficient and accurate method of estimation of spatially correlated errors in astrometric positions, parallaxes and proper motions obtained by space and ground-based astrometry missions. In our method, the simulated observational equations are set up and solved for the coefficients of scalar and vector spherical harmonics representing the output errors, rather than for individual objects in the output catalog. Both accidental and systematic correlated errors of astrometric parameters can be accurately estimated. The method is demonstrated on the example of the JMAPS mission, but can be used for other projects of space astrometry, such as SIM or JASMINE.
description: Accepted by AJ, to be published in 2012
Consistent treatment of coherent and incoherent energy transfer dynamics using a variational master equation
Creators: name: McCutcheon, Dara P. S.
name: Nazir, Ahsan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We investigate the energy transfer dynamics in a donor-acceptor model by developing a time-local master equation technique based on a variational transformation of the underlying Hamiltonian. The variational transformation allows a minimisation of the Hamiltonian perturbation term dependent on the system parameters, and consequently results in a versatile master equation valid over a range of system-bath coupling strengths, temperatures, and environmental spectral densities. While our formalism reduces to the well-known Redfield, Foerster and polaron forms in the appropriate limits, in general it is not equivalent to perturbing in either the system-environment or donor-acceptor coupling strengths, and hence can provide reliable results between these limits as well. Moreover, we show how to include the effects of both environmental correlations and non-equilibrium preparations within the formalism.
description: 13 pages, 6 figures, comments welcome. Published version, minor changes to text, references added
Time-variant infrastructures and dynamical adaptivity for higher degrees of complexity in autonomous music feedback systems: the Order from noise (2017) project
Creators: name: Sanfilippo, Dario
Publisher: name: Musica/Tecnologia
Year: 2018

description: The use of recursive time-variant networks for musical applications dates back to the 1960s with the seminal work of Gordon Mumma who implemented his own systems and circuits in the analogue domain. Practitioners like Nicolas Collins followed the same approach in the 1970s – particularly with works such as Pea Soup (1976) – and, in more modern times, this technique has been extended to the digital domain and thoroughly explored by composers such as Agostino Di Scipio and the author. The general framework for this approach is to establish several interdependent relationships among the information which is extracted from sound and the variables which affect sound itself, while also creating a structural coupling, i.e. a feedback loop, between information and sound processing. This configuration is the basis for the realisation of systems which can adapt – very broadly speaking – to the context they operate in, and that, under the right circumstances and implementations, can exhibit a complex autonomous behaviour, albeit maintaining a convincing variety over a long time span is a particularly challenging goal. The work presented here is based on a novel idea developed by the author, that is a time-variant network where the relationships between information and sound processing are themselves time-variant and context-dependent, resulting in a dynamical adaptivity, with the scope of enhancing the long-term variety and complexity of autonomous music systems. The author, after a discussion on adaptive systems which is necessary to better contextualise the conceptual and technical framework of the work, will proceed through a description of the system while providing connections to the artistic ideas and implications of this approach on the practice of live performance with autonomous systems.
description: Musica/Tecnologia, XI-XII (2017-2018)
Real-time In Situ Electron Spin Resonance Measurements on Fungal Spores of Penicillium digitatum during Exposure of Oxygen Plasmas
Creators: name: Ishikawa, Kenji
name: Moriyama, Hiroko
name: Tanaka, Hiromasa
name: Tamiya, Kazuhiro
name: Hashizume, Hiroshi
name: Ohta, Takayuki
name: Ito, Masafumi
name: Iseki, Sachiko
name: Takeda, Keigo
name: Kondo, Hiroki
name: Sekine, Makoto
name: Hori, Masaru
Publisher: name: arXiv
Year: 2012
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We report the kinetic analysis of free radicals on fungal spores of Penicillium digitatum interacted with atomic oxygen generated plasma electric discharge using real time in situ electron spin resonance (ESR) measurements. We have obtained information that the ESR signal from the spores was observed and preliminarily assignable to semiquinone radical with a g-value of around 2.004 and a line width of approximately 5G. The decay of the signal is possibly linked to the inactivation of the fungal spore. The real-time in situ ESR has proven to be a useful method to elucidate plasma-induced surface reactions on biological specimens.
description: 11 pages, 5 figures
Relating Timbre and Shape in the Audiovisual Composition S Phase
Creators: name: Putnam, Lance
Publisher: name: Musica/Tecnologia
Year: 2018

description: S Phase is a computer-generated audiovisual composition that was led by a desire to create an abstract form that had a sense of living and breathing and to associate sound and graphics on a deep level. This article discusses the motivation for the work, details of its construction and compositional interface, and some of the timbre-shape associations explored in the work. Basic sound synthesis parameters were used to control higher-level features of the graphical representation such as rotational and translational symmetry and roundedness.
description: Musica/Tecnologia, XI-XII (2017-2018)
Static and Fatigue Behaviour of Concrete Truss Girder Connection Reinforced with Double-Headed Glass FRP Bars
Creators: name: Hadizadeh Harandi, Marjan
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Engineering--Civil
subject: Truss
subject: Hybrid
subject: Precast
subject: Bridge
subject: Static
subject: Fatigue
subject: Double-headed GFRP bar
subject: CFFT

description: Glass fibre-reinforced polymer (FRP) materials have been recently employed in different reinforced concrete structures in order to eliminate the detrimental effects of steel corrosion and enhance durability of concrete structure. Therefore, the needs for research on the behaviour of glass FRP (GFRP) materials are increasing with the increase in their use in various applications. The research presented in this thesis focuses on investigating the static and fatigue performance of precast prestressed concrete truss girder connections reinforced with double-headed GFRP bars. For this application the efficiency of the anchoring heads of the individual double-headed GFRP bars under static and fatigue loading needs to be tested first. Therefore, a total of eighteen specimens of individual double-headed GFRP bars with each head embedded in a concrete-filled steel cylinder are tested. Three of the headed bars were tested under monotonic loading increasing from zero to failure. The remaining fifteen bars were tested under fatigue loading. A total of eight truss girder connections were tested. Two of the truss connections, one reinforced with 12-mm double-headed GFRP bars and one reinforced with 16-mm double-headed GFRP bars, were loaded monotonically to failure. The remaining six connections were reinforced with 16-mm double-headed GFRP bars and tested under fatigue loading of different ranges. The results of this research were compared with those of previous research on the similar connections reinforced with long double-headed steel bars and spliced single-headed steel bars.
Additional file 9: of Genome-wide analysis of three histone marks and gene expression in Paulownia fortunei with phytoplasma infection
Creators: name: Yan, Lijun
name: Fan, Guoqiang
name: Li, Xiaoyu
Publisher: name: figshare
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Virology

description: Table S2. Primer sequences of genes used for ChIP-qPCR (DOCX 14 kb)
On low-energy predictions of unification models inspired by F-theory
Creators: name: Jelinski, Tomasz
name: Pawelczyk, Jacek
name: Turzynski, Krzysztof
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The aim of this paper is to discuss phenomenological consequences of a particular unification model (Z_3 model) inspired by F-theory. The most distinctive feature of this model is a variety of (cosmologically feasible) options for the NLSP and NNLSP, beyond the usually considered benchmark scenarios.
description: LaTeX, 11 pages, 12 figures
The New Woman and Comedy: Form and Function on the Modern British Stage
Creators: name: Flynn, Rebecca
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Theater
subject: The New Woman
subject: Comedy
subject: First-wave feminism

description: This thesis focuses on female comic characters in modern drama as they relate to the emergence of first-wave feminism in late-nineteenth and early-twentieth-century Britain. More specifically, it examines the position of the figure of the new woman within the conventions of traditional comedy. Analyzing specific character traits and elements of dramatic composition that allow this figure to exist within the comic form, I consider how select playwrights deploy comedy in order to shape the reception of the new woman. Using three case studies that include parodies of Henrik Ibsen’s plays, suffrage comedy, and the work of George Bernard Shaw, I explore how comedy was used in different contexts to both empower and diminish the complexity of the new woman. I conclude that the comic new woman was defined by her reassessment and re-inscription on the modern stage as well as the social, political, and cultural change she facilitated.
Estremo d’ombra: an interactive electronic composition
Creators: name: Morciano, Lara
Publisher: name: Musica/Tecnologia
Year: 2018

description: In Estremo d’ombra, for five soloists and electronics (2015), an interactive system was developed in order to enable the synchronisation between the performers and the live electronics – consisting of real-time processing and synthesis – to be composed in detail. This system led to the creation of a ‘centralised’ score for the electronics realised in the Antescofo programming language, which pilots electroacoustic processes executed in the SuperCollider and Max/MSP environments and displays scores for the performers in openFrameworks. The Antescofo system allows for the expression of temporally complex interactions involving the instrumentalists, rendering the composition of the real-time electronics more dynamic and expressive. This system eliminated the need for a conductor or a pedal of activation, thereby allowing the performers to interact and move more freely. The staging of the work is emphasised by lighting and a symbolic dramatic narrative.
description: Musica/Tecnologia, XI-XII (2017-2018)
Poster: Proximity, Frequency and Duration of Close Patient Contacts among Nurses in a COVID-19 Intensive Care Unit: An Electronic Measurement
Creators: name: Neuwirth, Meike
name: Pommeranz, Tanja
name: Mattner, Frauke
name: Otchwemah, Robin
Publisher: name: Zenodo
Year: 2021
Subjects: surveillance
SARS-Cov-2
COVID-19
CLOSE PATIENT CONTACTS
ELECTRONIC MEASUREMENT

description: Introduction:
 SARS-CoV-2 is mainly transmitted via respiratory ingestion of virus-containing particles. In principle, the
 likelihood of exposure to infectious particles of any size is increased within a distance of 1-2 meters to an infected person.
 Nurses are particularly at risk of contracting COVID-19 from patients due to the close patient contact and the number of
 intensive contacts. Objectives:
 It has not yet been investigated, how long and often nurses are exposed to a close patient contact due to the
 intensive care during their service. The study aimed to determine the duration and frequency of close patient contacts
 between nurses and COVID-19 patients during nursing activities. Methods:
 In the period from 14.12.2020 to 28.02.2021, 12 beds of a COVID-19 pulmonary intensive care unit were equipped with Bluetooth Low Energy (BLE) transmitters and 12 nurses were equipped with BLE wearables (Clinaris GmbH, Germany) in order to record the frequency and duration of patient contact as well as the distance of nurses to the headboard (face) of the patient bed. For the data evaluation, only the measurement data with at least two directly consecutive (chained) measurement contacts longer than 1 sec. and a maximum distance of 1.5 m from the patient's head were considered as relevant. Results:
 Per eight-hour shift a nurse had an average of 73.6 relevant patient contacts with a mean length of stay of 45.7 sec. per contact. The most frequent and longest contacts occurred during the early shift (6:00-14:00 o'clock) with an average number of 87.7 contacts and an average duration of 47.9 sec. This was followed by the late shift (14:00-22:00; 85.1 contacts; duration 44.1 sec.) and the night shift (22:00-6:00; 42.6 contacts; 44.6 sec.). A nurse was closer than 1.5 m to patients' heads for an average of 60.29 min. per shift. Conclusion:
 The results show for the first time how many relevant contacts take place when caring for Covid-19 intensive care patients and provide initial indications for assessing the risk of infection in the daily work of intensive care nurses. In general, nurses work approx. 1/8 of their working time closer than 1.5 m to the head area of COVID-19 infected patients and are, directly exposed to SARS-CoV-2 within the typical droplet distance.
Optimization of Li-ion Conductivity of Garnet-type Li5La3Nb2O12 by Nb-site Substitution Approach
Creators: name: Pinzaru, Dana
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Chemistry--Physical
subject: Garnet-type
subject: Li-ion Electrolytes
subject: Solid State Batteries

description: Solid state Li ion electrolytes based on the garnet type crystal structure have been successfully synthesized using the ceramic method. The approach employed in this thesis was doping of the Nb-site in Li5La3Nb2O12 with Sm and Gd and Li stuffing into the garnet-like oxides for charge balance. The resulting family of compounds have a nominal formula Li5+2xLa3Nb2-xSmxO12 (0 ≤ x ≤ 0.7) and Li5+2xLa3Nb2-xGdxO12 (0 ≤ x ≤ 0.45). Experimental techniques used for the characterization of the solid state materials include powder X-ray diffraction (PXRD) to determine the crystal structure, scanning electron microscopy (SEM) to analyze the microstructure, energy dispersive spectroscopy (EDS) to confirm the elemental composition, AC impedance spectroscopy to determine the lithium ion conductivity Fourier transform infrared spectroscopy (FTIR) to confirm the presence of OH- and CO32- groups in the samples and thermogravimetric analysis (TGA) to test the thermal stability of the compound. The most promising samples were the x = 0.3 member of the Sm-doped family and the x = 0.45 member of the Gd-doped family. Li5.6La3Nb1.7Sm0.3O12 showed a conductivity of 5.84 x 10-5 S cm-1 at room temperature, with an activation energy of 0.38 eV in the 25-225 °C. temperature range Li5+2xLa3Nb2-xGdxO12 showed the highest conductivity of 1.91 x 10-5 S cm-1 at room temperature with an activation energy of 0.38 eV in the temperature range 25-225 °C. Both show an order of magnitude higher conductivity than the parent compound, Li5La3Nb2O12.
Social and psychological impact of musical collective creative processes in virtual environments; The Avatar Orchestra Metaverse in Second Life
Creators: name: Martín, Gema F.B.
Publisher: name: Musica/Tecnologia
Year: 2018

description: Social networks, date webs, multi-player online games and other technological resources enabling remote personal interactions have a rising social impact that is changing some paradigms of the human relationships. The rise of such impact is determining that governs are adapting their legal system to affront new challenges arising from those new technologies. In this paper, it has been assessed whether personal interaction trough immersive virtual environments allow, or even enhances, collective creativity thanks to technological features as described below. First, the possibility to overcome technological barriers found in the physical world. Second, a different symbolic connection emerges from the lack of face-to-face contact. Third, individuals should focus their attention on the environment, in this case, Second Life (SL), during the rehearsal. Fourth, the wide diversity of age, ethnic and geographical features of the participants. To assess these insights, a case-study, focused on the Avatar Orchestra Metaverse (AOM), an orchestra based on SL, has been performed based on a participative observation, where valuable parameters have been identified during an immersive experience of the researcher. After then, participants of the case-study orchestra were subjected to specific test describing their experience and impressions at the social and creative levels in Second Life. Thus, it has been found that, in the AOM, the virtual environment could have created an appropriate space promoting the collective creativity.
description: Musica/Tecnologia, XI-XII (2017-2018)
Manipulating infrared photons using plasmons in transparent graphene superlattices
Creators: name: Yan, Hugen
name: Li, Xuesong
name: Chandra, Bhupesh
name: Tulevski, George
name: Wu, Yanqing
name: Freitag, Marcus
name: Zhu, Wenjuan
name: Avouris, Phaedon
name: Xia, Fengnian
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Superlattices are artificial periodic nanostructures which can control the flow of electrons. Their operation typically relies on the periodic modulation of the electric potential in the direction of electron wave propagation. Here we demonstrate transparent graphene superlattices which can manipulate infrared photons utilizing the collective oscillations of carriers, i.e., plasmons of the ensemble of multiple graphene layers. The superlattice is formed by depositing alternating wafer-scale graphene sheets and thin insulating layers, followed by patterning them all together into 3-dimensional photonic-crystal-like structures. We demonstrate experimentally that the collective oscillation of Dirac fermions in such graphene superlattices is unambiguously nonclassical: compared to doping single layer graphene, distributing carriers into multiple graphene layers strongly enhances the plasmonic resonance frequency and magnitude, which is fundamentally different from that in a conventional semiconductor superlattice. This property allows us to construct widely tunable far-infrared notch filters with 8.2 dB rejection ratio and terahertz linear polarizers with 9.5 dB extinction ratio, using a superlattice with merely five graphene atomic layers. Moreover, an unpatterned superlattice shields up to 97.5% of the electromagnetic radiations below 1.2 terahertz. This demonstration also opens an avenue for the realization of other transparent mid- and far-infrared photonic devices such as detectors, modulators, and 3-dimensional meta-material systems.
description: under review
ANTIDINAMICA (2015-2016). Da 1 a 4 sassofoni e live electronics, per Gianpaolo Antongirolami
Creators: name: Doati, Roberto
Publisher: name: Musica/Tecnologia
Year: 2018

description: ANTIDINAMICA is the first number of “Architetture invisibili”, a series of compositions devoted to form and acoustic instrument hidings. The compositional process will be described in detail. It starts with a transformation of a recorded saxophone improvisation by Gianpaolo Antongirolami. The spectral analysis of this transformation will generate the score for the four saxophones in ANTIDINAMICA. The performers can choose and change the metronome on every page, as well as what and how many staves to play – there are 6 in each page – but within a defined time length. Then they continue improvising on what in their memory the score left. The live electronics performer freely improvises on the parameters of an environment consisting of a 8 tracks filtered impulses convolution sent to 4 multitaps delay.
description: Musica/Tecnologia, XI-XII (2017-2018)
Dark goo: Bulk viscosity as an alternative to dark energy
Creators: name: Gagnon, Jean-Sebastien
name: Lesgourgues, Julien
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a simple (microscopic) model in which bulk viscosity plays a role in explaining the present acceleration of the universe. The effect of bulk viscosity on the Friedmann equations is to turn the pressure into an "effective" pressure containing the bulk viscosity. For a sufficiently large bulk viscosity, the effective pressure becomes negative and could mimic a dark energy equation of state. Our microscopic model includes self-interacting spin-zero particles (for which the bulk viscosity is known) that are added to the usual energy content of the universe. We study both background equations and linear perturbations in this model. We show that a dark energy behavior is obtained for reasonable values of the two parameters of the model (i.e. the mass and coupling of the spin-zero particles) and that linear perturbations are well-behaved. There is no apparent fine tuning involved. We also discuss the conditions under which hydrodynamics holds, in particular that the spin-zero particles must be in local equilibrium today for viscous effects to be important.
description: 21 pages, 14 figures. References added, typos corrected, figure 2 corrected, a few comments added, results unchanged
Three years of fragments: music, sound design, and sketching
Creators: name: Cera, Andrea
Publisher: name: Musica/Tecnologia
Year: 2018

description: This article describes an ongoing process, started in 2014, which brings together scientific research, artistic investigation, sound design tools development, and cooperation between various entities, institutional and non-institutional: the European project SkAT-VG, the independent Swiss platform Plakart, the Art Center of Château La Coste, social media. The artistic output of this process consists of series of sketches and fragments ([I titoli che seguono entro la parentesi tonda vanno tutti in corsivo] Pink Squirrels; S’i’ Fosse Suono; after the Gate-Machines; The Brown Lipstick Sketches). The focus on sketching activities (in the SkAT-VG project) and the fragmented nature of the Internet (in the Plakart platform) has driven me to develop autonomous narrative frameworks to unify a seemingly disparate collection of short forms. I introduce my presentation with a synopsis of my aesthetic position, which revolves around the interference between different, or even incompatible, cultural paradigms.
description: Musica/Tecnologia, XI-XII (2017-2018)
Hydraulic Fracturing and Flow-back Simulation in Unconventional Tight Reservoirs
Creators: name: Lin, Menglu
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Engineering--Petroleum
subject: Reservoir simulation, Hydraulic fracturing, Flow-back, Tight reservoirs

description: At present, combination of the multistage hydraulic fracturing and horizontal wells has become a widely used technology in stimulating unconventional tight reservoirs in Western Canadian Sedimentary Basin (WCSB). It is important to understand hydraulic fracture propagation mechanism, effects of their properties and controlling factors affecting flow-back recovery. In this thesis, based on tight reservoir models in WCSB, firstly we examine different fracture geometry distributions and further discuss their effects on well productions. Then reservoir simulation coupled with rock geomechanics is employed to perform dynamic hydraulic fracturing for predicting hydraulic fracture dimensions and simulating fracturing liquid distribution. At last, Design of Experiments and response surface methodology are conducted to explore well operational parameters affecting flow-back recovery and net present value (NPV). This study provides new insights on the hydraulic fracturing and can be a reference for fracturing treatments in unconventional tight reservoirs.
Role of the Alzheimer's predisposition factor CD2AP in brain endothelial cells
Creators: name: Gunn, Colin
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Biology--Cell
subject: Biology--Molecular
subject: Neuroscience
subject: CD2AP
subject: Alzheimer's
subject: Brain

description: Alzheimer disease (AD) is the most prevalent form of dementia in the elderly. Vascular degeneration plays a critical role in AD pathogenesis. For instance, APOE4 allele, the main genetic risk factor for AD, is linked to reduced cerebral blood flow and increased blood brain barrier (BBB) leakiness. CD2-associated protein (CD2AP) is an adaptor protein that regulates receptor endocytosis and recycling. Two single nucleotide polymorphisms in CD2AP are associated with higher risk for AD and levels of CD2AP are decreased in lymphocytes of sporadic AD patients. Recent human studies also show that CD2AP is linked to the burden of Aβ plaques, memory deficits and modulates AD symptoms in APOE4 patients. Interestingly, CD2AP is enriched in the brain microvascular endothelial cells (BMECs), a key component of the brain microvasculature. However, the basic functions of CD2AP in BMECs and its contribution to brain vasculature dysfunction in AD remain totally unknown. Here we show that siRNA-mediated depletion of CD2AP in both human brain endothelial cell line and mouse primary BMECs leads to the deregulation of proteins involved in AD pathogenesis. Of particular interest, we found that CD2AP interacts with one of these proteins, ApoER2, the receptor for ApoE that is targeted to degradation upon ligation by AD allele ApoE4. Similar to ApoE4, CD2AP loss reduced the levels of ApoER2. Finally, we discovered that downregulation of ApoER2 in CD2AP-depleted cells is modulated by Rab5 GTPase activity.
Lost in feedback (2014): soluzioni personali di musica mista tra il teatro musicale e la performance visuale
Creators: name: Cacciatore, Maurilio
Publisher: name: Musica/Tecnologia
Year: 2018

description: Lost in feedback is a work for electric vibraphone, percussions, stage performer and live electronics. The add of some captors under the keys of the vibraphone together with a series of non conventional techniques transform the sound in order to relate acoustic sources and electronic treatments. The canvas painted live by the stage performer also contributes to the electronics along the piece by a series of captors placed under the structure that holds the surface and the artist. The title of the piece refers to the strategy adopted for the realisation of the sound files and the live capturing; real-time and pre-recorded Larsen effects sustain the instrumental playing and use actively the custom spazialization adopted. A contact loudspeaker placed on a Timpano uses the instrument like a resonator and the vibraphone is amplified through an electric guitar amplifier. The software for managing the electronics has been programmed using a Max package of mine based on a modules collection for the live electronics combined with acoustic instruments called MMixte.
description: Musica/Tecnologia, XI-XII (2017-2018)
Waveguide single-photon detectors for integrated quantum photonic circuits
Creators: name: Sprengers, J. P.
name: Gaggero, A.
name: Sahin, D.
name: Nejad, S. Jahanmiri
name: Mattioli, F.
name: Leoni, R.
name: Beetz, J.
name: Lermer, M.
name: Kamp, M.
name: Höfling, S.
name: Sanjines, R.
name: Fiore, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The generation, manipulation and detection of quantum bits (qubits) encoded on single photons is at the heart of quantum communication and optical quantum information processing. The combination of single-photon sources, passive optical circuits and single-photon detectors enables quantum repeaters and qubit amplifiers, and also forms the basis of all-optical quantum gates and of linear-optics quantum computing. However, the monolithic integration of sources, waveguides and detectors on the same chip, as needed for scaling to meaningful number of qubits, is very challenging, and previous work on quantum photonic circuits has used external sources and detectors. Here we propose an approach to a fully-integrated quantum photonic circuit on a semiconductor chip, and demonstrate a key component of such circuit, a waveguide single-photon detector. Our detectors, based on superconducting nanowires on GaAs ridge waveguides, provide high efficiency (20%) at telecom wavelengths, high timing accuracy (60 ps), response time in the ns range, and are fully compatible with the integration of single-photon sources, passive networks and modulators.
description: 11 pages, 4 figures
Epitaffio di Silicio. Traccia per improvvisazione in live coding
Creators: name: Buso, Nicola
Publisher: name: Musica/Tecnologia
Year: 2018

description: The live coding practice entails many effects on musical activities for composers, performers and audience, in a hypothetical ‘theater of writing’. The new paradigm involves a new approach to the musical experience in its entirety, becoming not only a musical reality, but also a cultural fact, determined by new media.
description: Musica/Tecnologia, XI-XII (2017-2018)
The Roles of the Smc5/6 Complex in Heterochromatin Maintenance at Telomeres
Creators: name: Moradi Fard, Sareh
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Biology--Cell
subject: Genetics
subject: FOS: Biological sciences
subject: Biology--Molecular
subject: Biochemistry
subject: S. cerevisiae
subject: Telomere
subject: Sir4
subject: Smc5/6
subject: Rif2
subject: Silencing
subject: Heterochromatin

description: SMC proteins constitute the core members of the Smc5/6, cohesin and condensin complexes. I demonstrate that Smc5/6 is present at telomeres throughout the cell cycle and its association with chromosome ends is dependent on Nse3, a subcomponent of the complex. Cells harboring a temperature sensitive mutant, nse3-1, are defective in Smc5/6 localization to telomeres and have slightly shorter telomeres. Shorter telomeres in nse3-1 cells correlate with a loss of Est2 association to telomeres. Nse3 interacts physically and genetically with two Rap1-binding factors, Rif2 and Sir4. When nse3-1 is combined with rif2Δ, there is a partial reversion in telomere elongation resulting from the loss of RIF2 that is independent of homologous recombination (HR). Shortening of telomeres by nse3-1 appears to be specific to rif2Δ and not a general function towards long telomeres as telomere length of nse3-1/rif1Δ cells is indistinguishable from telomere length in rif1Δ cells. Using genetic approaches, I also find that nse3-1 epistatically relates to positive regulators of telomerase, Tel1 and YKu70. Reduction in telomere-associated Smc5/6 leads to defects in telomere clustering, dispersion of the silencing factor, Sir4, and a loss in transcriptional repression for sub-telomeric genes and noncoding telomeric repeat-containing RNA (TERRA). SIR4 recovery at telomeres is reduced in cells lacking Smc5/6 functionality and vice versa. However, nse3-1/sir4Δ double mutants show additive defects for telomere shortening and TERRA regulation indicating the contribution of Smc5/6 to telomere homeostasis is only in partial overlap with SIR factor silencing. These findings support a role for Smc5/6 in telomere maintenance that go beyond its canonical role(s) in HR-mediated events during replication and telomere elongation.
title: Crash Modification Factor Recommendation List
Creators: name: Souleyrette, Reginald R.
name: Tanzen, Riana
name: Green, Eric R.
name: Staats, William Nicholas
name: Lause, Federico
Publisher: name: Kentucky Transportation Center, University of Kentucky
Year: 2020
Subjects: subject: FOS: Civil engineering

description: Practitioners use Crash Modification Factors/Functions (CMFs) to calculate the number of crashes expected once a countermeasure has been implemented. When evaluating design alternatives, CMFs can be used in conjunction with safety performance functions (SPFs) to derive crash predictions. The Federal Highway Administration (FHWA) maintains the CMF Clearinghouse as a repository for CMFs. Contributions are submitted by researchers across the U.S., Canada, and throughout the world. Typically, multiple CMFs are associated with a single countermeasure. Some CMFs only apply to specific facility or crash types. Furthermore, CMF quality varies, and some only apply to specific facility and/or crash types, regions, or times. Using the Clearinghouse to identify an appropriate CMF for a given situation demands considerable time and significant expertise. This report describes the development and implementation of a spreadsheet-based tool that Kentucky Transportation Cabinet staff and the agency’s design consultants can use to select CMFs most appropriate for the state’s highways and conditions. Guidance instructs users on use of the tool. A web-based form was also developed, which must be filled out and submitted to KYTC’s CMF committee when a CMF is planned for use on a project.
description: © 2020 University of Kentucky, Kentucky Transportation Center
Religious Print Culture and the British and Foreign Bible Society in Canada, 1820-1904
Creators: name: Barnard, Stuart Wayne
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Economics--History
subject: History--Canadian
subject: History--Church
subject: Religion
subject: Bible
subject: Bible societies
subject: Canada
subject: evangelicalism
subject: print culture
subject: British and Foreign Bible Society

description: This study addresses the central question of how Canadians came to obtain the bibles they read in nineteenth century Canada. Historians of religion in Canada have recognized the importance of evangelicalism in nineteenth century Canada, but have rooted their analyses largely in denominational and intellectual frameworks. This study seeks to examine Protestant evangelicalism through its outworking in the British and Foreign Bible Society, one of the largest voluntary societies in Canada in this period. The Bible Society’s organization, its methods in Bible distribution, and its expansion across Canada in the nineteenth century reveal the enormous influence of evangelical Protestant faith in English-speaking Canada. The Bible Society garnered considerable support across Protestant denominations, building a broad coalition of evangelicals whose active involvement in the BFBS’s enterprise was fuelled by their commitment to religious voluntarism and the centrality of the Bible in an individual’s salvation. The BFBS’s leaders in Canada defined themselves using popular ideas of anti-Catholicism, and used anecdotes of Catholic opposition to their Bible enterprise to highlight the importance of liberty and individual freedom in matters of faith and conscience. By the end of the nineteenth century, the Bible Society operated within a competitive book trade in which emerging consumer tastes created new demands on the Bible Society that challenged the way it operated as both a religious organization and a competitive bookseller. The BFBS’s enterprise in Canada in the nineteenth century highlights the importance of the evangelical movement in Canadian society and offers a unique lens on religion and print culture in this period.
Iterative summation of path integrals for nonequilibrium molecular quantum transport
Creators: name: Hützen, R.
name: Weiss, S.
name: Thorwart, M.
name: Egger, R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We formulate and apply a nonperturbative numerical approach to the nonequilibrium current, $I(V)$, through a voltage-biased molecular conductor. We focus on a single electronic level coupled to an unequilibrated vibration mode (Anderson-Holstein model), which can be mapped to an effective three-state problem. Performing an iterative summation of real-time path integral (ISPI) expressions, we accurately reproduce known analytical results in three different limits. We then study the crossover regime between those limits and show that the Franck-Condon blockade persists in the quantum-coherent low-temperature limit, with a nonequilibrium smearing of step features in the $IV$ curve.
description: 4 pages, 4 figures
Depressive patients are more impulsive and inconsistent in intertemporal choice behavior for monetary gain and loss than healthy subjects- an analysis based on Tsallis' statistics
Creators: name: Takahashi, Taiki
name: Oono, Hidemi
name: Inoue, Takeshi
name: Boku, Shuken
name: Kako, Yuki
name: Kitaichi, Yuji
name: Kusumi, Ichiro
name: Masui, Takuya
name: Nakagawa, Shin
name: Suzuki, Katsuji
name: Tanaka, Teruaki
name: Koyama, Tsukasa
name: Radford, Mark H. B.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Other Quantitative Biology (q-bio.OT)
subject: FOS: Biological sciences

description: Depression has been associated with impaired neural processing of reward and punishment. However, to date, little is known regarding the relationship between depression and intertemporal choice for gain and loss. We compared impulsivity and inconsistency in intertemporal choice for monetary gain and loss (quantified with parameters in the q-exponential discount function based on Tsallis' statistics) between depressive patients and healthy control subjects. This examination is potentially important for advances in neuroeconomics of intertemporal choice, because depression is associated with reduced serotonergic activities in the brain. We observed that depressive patients were more impulsive and time-inconsistent in intertemporal choice action for gain and loss, in comparison to healthy controls. The usefulness of the q-exponential discount function for assessing the impaired decision-making by depressive patients was demonstrated. Furthermore, biophysical mechanisms underlying the altered intertemporal choice by depressive patients are discussed in relation to impaired serotonergic neural systems. Keywords: Depression, Discounting, Neuroeconomics, Impulsivity, Inconsistency, Tsallis' statistics
Land Ice Monitoring via GRACE and Satellite Altimetry in the Canadian Arctic Archipelago
Creators: name: Tsali, Iliana
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Geodesy
subject: Geodesy
subject: Hydrology
subject: Atmospheric Sciences
subject: FOS: Earth and related environmental sciences
subject: Remote Sensing

description: The Canadian Arctic Archipelago (CAA) was remarked as the third most significant contributor to the global sea level rise between 2003 and 2009, containing one third of the world’s freshwater as land ice (Gardner et al., 2011). Continuous monitoring of the long-term mass variability of the CAA is essential knowledge for gaining insight about their forthcoming impact due to climate change. The scope of this thesis is to determine independent mass balance estimates from GRACE gravity and ICESat laser altimetry data for both the Northern and the Southern Canadian Arctic (NCA; SCA), compare both estimates and assess them with respect to previous studies, while discussing the reasons of the potential discrepancies existing. GRACE data are available as spherical harmonic coefficients (Level-2) express the gravity field and they are expanded up to a certain degree and order. This hampers the recovery of regional scale mass anomalies, which need knowledge of higher spatial detail. The proposed approach reconstructs spatial averaging basin functions that mask the glaciated areas of the NCA and SCA and fits GRACE-Stokes coefficients to isolate the ice-signal. This methodology has been applied to large river basins and ice sheets, however the present algorithm is applied for the first time to ice caps and glaciers. Due to the basins’ nature of signal leaking outside the basin, an estimate of the basin leakage error is accounted as well. High correlation in the Stokes coefficients of shorter wavelengths produces artificial noise which has to be filtered. Four different filters were tested and assessed with respect to geophysical signal attenuation they induced. The impact of the different filtering has been neglected for ice applications up to now, however this thesis highlights mass trends differences up to 8 Gt/yr. The GIA and hydrology reduced GRACE mass balance was -27.5 ± 4.1 Gt/yr for the NCA and -19.8 ± 2.5 Gt/yr for the SCA from 2003 to 2009. 5-year-intervals were estimated between 2003 and 2014 and accelerating mass losses of 50-55 Gt/yr for the NCA and 20-25 Gt/yr for the SCA were noticed. ICESat repeat tracks are not repeated exactly, while the elevation sampling is relatively sparse for glaciers, ICESat operated 2-3 times/yr. The ICESat mass changes derivation involved the retrieval of elevation changes by fitting elevations into boxes, and the conversion to volume changes using Ordinary Kriging and mass changes assuming a constant ice density. The GIA-free ICESat mass changes of -39.4 ± 10.4 Gt/yr for the NCA and -23.9 ± 6.1 Gt/yr for the SCA showed greater mass losses compared with GRACE in the same period. The potential causes are discussed analytically and justified sufficiently in this thesis.
Correlations in the Ising antiferromagnet on the anisotropic kagome lattice
Creators: name: Apel, Walter
name: Everts, Hans-Ulrich
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the correlation function of middle spins, i. e. of spins on intermediate sites between two adjacent parallel lattice axes, of the spatially anisotropic Ising antiferromagnet on the kagome lattice. It is given rigorously by a Toeplitz determinant. The large-distance behaviour of this correlation function is obtained by analytic methods. For shorter distances we evaluate the Toeplitz determinant numerically. The correlation function is found to vanish exactly on a line J_d(T) in the T-J (temperature vs. coupling constant) phase diagram. This disorder line divides the phase diagram into two regions. For J less than J_d(T) the correlations display the features of an unfrustrated two-dimensional Ising magnet, whereas for J greater than J_d(T) the correlations between the middle spins are seen to be strongly influenced by the short-range antiferromagnetic order that prevails among the spins of the adjacent lattice axes. While for J less than J_d(T) there is a region with ferrimagnetic long-range order, the model remains disordered for J greater than J_d(T) down to T=0.
description: 26 pages, 9 figures, published version
Orbital magnetic susceptibility of finite-sized graphene
Creators: name: Ominato, Yuya
name: Koshino, Mikito
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the orbital magnetism of graphene ribbon in the effective-mass approximation, to figure out the finite-size effect on the singular susceptibility known in the bulk limit. We find that the susceptibility at T = 0 oscillates between diamagnetism and paramagnetism as a function of Fermi energy, in accordance with the subband structure formed by quantum confinement. In increasing T, the oscillation rapidly disappears once the thermal broadening energy exceeds the subband spacing, and the susceptibility approaches the bulk limit i.e., a thermally broadened diamagnetic peak centered at zero energy point. The electric current supporting the diamagnetism is found to flow near the edge with a depth which proportional to reciprocal of T, with v being the band velocity, while at T = 0 the current distribution spreads entirely in the sample reflecting the absence of the characteristic wavelength in graphene. The result is applied to estimate the three-dimensional random-stacked multilayer graphene, where we show that the external magnetic field is significantly screened inside the sample in low temperatures, in a much stronger manner than in graphite.