cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mechanistic insights into the inflammatory pathogenesis of visual disturbances after traumatic brain injury
Creators: name: Evans, Lucy Pratt
Publisher: name: University of Iowa
Year: 2022
Subjects: blast
retina
TBI
public abstract
Inflammation
Traumatic Brain Injury
Vision

description: Traumatic brain injuries (TBI) cause long-lasting physical, cognitive, and psychological disorders, including persistent visual impairment. The retina is a central nervous system (CNS) tissue that is especially vulnerable to blast-induced TBI (bTBI). Individuals with bTBI often suffer from visual dysfunction which may manifest months to years after the initial exposure. While patients can report a wide range of problems, little is known about the molecular changes in both the retina and higher order visual processing centers that lead to visual dysfunction. With TBI mortality decreasing due to advancements in medical and protective technologies, there is growing interest in understanding the pathology of visual dysfunction after bTBI. No known therapies are currently utilized in humans to lessen the lingering and often serious symptoms. In this thesis, I discuss visual outcomes after TBI and possible targets for clinical drug applications. I established that while ocular injury is present in multiple murine TBI models, the pathologic changes seen can vary widely. However, one commonality I observed across models was a heightened inflammatory response (Chapter 2) resulting in secondary injury that exacerbates initial neuronal insult and could be a potential therapeutic strategy for treating TBI. The interleukin-1 (IL-1) pathway is a major contributor to the neuroinflammatory response within the brain after TBI. This pathway can be easily targeted by the drug anakinra, an IL-1 receptor type I (IL-1RI) antagonist that is currently utilized in humans for other inflammatory conditions. Anakinra was successfully repurposed and could prevent visual deficits arising from retinal ganglion cell (RGC) dysfunction in a mouse model of bTBI (Chapter 3).
description: Using mice with genetic mutations in portions of the IL-1 pathway, we attempted to further characterize the important players in visual dysfunction after bTBI. These studies again implicated the IL-1 pathway as a causative agent of RGC damage after blast, however, genetic deletion from birth did not result in a complete rescue from the damaging visual out comes caused by bTBI. A separate analysis revealed that biological sex does not have an effect on the visual outcomes evaluated after bTBI. Insight gained from these studies may eventually be used to design novel, targeted, TBI therapies to help patients have better, longer lives.
The Herschel virgo cluster survey - XIV. Transition-type dwarf galaxies in the virgo cluster
Creators: name: De Looze, I.
name: Baes, M.
name: Boselli, A.
name: Cortese, Luca
name: Fritz, J.
name: Auld, R.
name: Bendo, G. J.
name: Bianchi, S.
name: Boquien, M.
name: Clemens, M.
name: Ciesla, L.
name: Davies, J.
name: di Serego Alighieri, S.
name: Grossi, M.
name: Jones, A.
name: Madden, S. C.
name: Pappalardo, C.
name: Pierini, D.
name: Smith, M. W. L.
name: Verstappen, J.
name: Vlahakis, C.
name: Zibetti, S.
Publisher: name: Swinburne
Year: 2024

description: We use dust scaling relations to investigate the hypothesis that Virgo cluster transition-type dwarfs are infalling star-forming field galaxies, which is argued based on their optical features (e.g. discs, spiral arms and bars) and kinematic properties similar to late-type galaxies. After their infall, environmental effects gradually transform them into early-type galaxies through the removal of their interstellar medium and quenching of all star formation activity. In this paper, we aim to verify whether this hypothesis holds using far-infrared diagnostics based on Herschel observations of the Virgo cluster taken as part of the Herschel Virgo Cluster Survey. We select transition-type objects in the nearest cluster, Virgo, based on spectral diagnostics indicative for their residual or ongoing star formation. We detect dust (Md ~ 105-6 M⊙) in 36 per cent of the transition-type dwarfs located on the high end of the stellar mass distribution. This suggests that the dust reservoirs present in non-detections fall just below the Herschel detection limit (≲1.1 × 105M⊙). Dust scaling relations support the hypothesis of a transformation between infalling late-type galaxies to quiescent low-mass spheroids governed by environmental effects, with dust-tostellar mass fractions for transition-type dwarfs in between values characteristic for late-type objects and the lower dust fractions observed in early-type galaxies. Several transition-type dwarfs demonstrate blue central cores, hinting at the radially outside-in removal of gas and quenching of star formation activity. The fact that dust is also confined to the inner regions suggests that metals are stripped in the outer regions along with the gas. In the scenario of most dust being stripped from the galaxy along with the gas, we argue that the ejected metals by transition-type dwarfs significantly contribute to the enrichment of the intracluster medium over the lifetime of the Virgo cluster. The accretion of gas through tidal interactions and reignition of star formation in the centres of transition-type dwarfs could provide an alternative explanation for the observed dust scaling relations and blue central cores.
Multichannel photonic networks.
Creators: name: Savov, Emil I.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Engineering, Electronics and Electrical.

description: This thesis presents several alternatives for fibre-optic local and metropolitan area networks. The issues considered are mainly related to the physical layer of the networks, i.e., the topology and the optical communications problems. The following approaches were considered in more detail: photonic switching using spatial light modulators; subcarrier-multiplexing techniques using direct optical detection, and in particular the transmission of 64-QAM signals by optical fibre; and subcarrier-multiplexing techniques combined with coherent optical detection. The spatial light modulator appears to be one of the most promising means for building a large-size (e.g., 1000 $\times$ 1000) optical space switch. The main constraints are the attenuation of the optical signal and the crosstalk between the channels. Other problems such as fan-in and fan-out are also addressed. Theoretical and experimental results are presented on the fibre-optic transmission of microwave 64-QAM signals at 90 Mb/s rate. Two important methods of improving the system performance are discussed and demonstrated: laser reflection-induced intensity noise minimization, and error-correction coding using a self-orthogonal convolutional code. The applicability of this transmission technique to the distribution of digital video services is assessed. The concept of photonic networks which use subcarrier-multiplexing techniques together with coherent optical detection is presented. The different radio and optical modulation formats that can be used are investigated and compared for several system modes of operation. The effects of laser phase noise on the system performance are also addressed. An 8-port homodyne phase-diversity receiver is analyzed theoretically.
Handlungsempfehlungen zur Weiterentwicklung des Kompetenzzentrums Nachhaltiger Konsum
Creators: name: Muster, Viola
name: Wagner, Masha
name: Fischer, Corinna
Publisher: name: Umweltbundesamt
Year: 2023
Subjects: subject: Nachhaltiger Konsum
subject: Öffentliche Einrichtung
subject: Nachhaltigkeitspolitik
subject: Öffentliche Institution
subject: Nationales Programm für nachhaltigen Konsum
subject: Wirtschaft | Konsum
subject: Nachhaltigkeit | Strategien | Internationales

description: Nachhaltiger Konsum ist ein Querschnittsthema der Bundesregierung. Entsprechend sind auch viele unterschiedliche Ministerien und Behörden für die Förderung eines nachhaltigen Konsums in Deutschland verantwortlich. Im Februar 2016 wurde das Nationale Programm für Nachhaltigen Konsum (NPNK) von der Bundesregierung verabschiedet. Für die institutionelle Begleitung des Programms wurden eine Interministerielle Arbeitsgruppe Nachhaltiger Konsum (IMA NK) und das Kompetenzzentrum Nachhaltiger Konsum (KNK) gegründet. Zudem wurde zur Einbindung von Stakeholdern das Nationale Netzwerk Nachhaltiger Konsum (NNNK) initiiert. Der vorliegende Bericht zeigt auf, unter welchen Ausgangsbedingungen des KNK gegründet wurde und gibt Empfehlungen, wie das KNK weiterentwickelt werden sollte, um seine vorhandenen Potentiale unter den gegebenen Bedingungen bestmöglich auszuschöpfen. Der vorliegende Bericht wurde im September 2020 fertiggestellt. Quelle: Forschungsbericht
description: Sustainable consumption is a cross-cutting issue of the Federal Government. Accordingly, many different ministries and authorities are also responsible for promoting sustainable consumption in Germany. In February 2016, the National Programme for Sustainable Consumption (NPNK) was adopted by the Federal Government. An Interministerial Working Group on Sustainable Consumption (IMA NK) and the Competence Centre for Sustainable Consumption (KNK) were founded to provide institutional support for the programme. In addition, the National Network for Sustainable Consumption (NNNK) was initiated to involve stakeholders. This report shows the initial conditions under which the KNK was founded and makes recommendations on how the KNK should be further developed in order to make the best possible use of its existing potential under the given conditions. This report was completed in September 2020. Quelle: Forschungsbericht
description: Im Februar 2016 wurde das Nationale Programm für Nachhaltigen Konsum (NPNK) von der Bundesregierung verabschiedet. Für die institutionelle Begleitung des Programms wurde u.a. das Kompetenzzentrum Nachhaltiger Konsum (KNK) gegründet. Der Bericht analysiert die Arbeitsgrundlagen bzw. Ausgangsbedingungen des KNK und entwickelt aufbauend auf der Analyse anderer Kompetenzzentren in Deutschland Handlungsempfehlungen zur strategischen und operativen Weiterentwicklung des KNK.
RESEARCH OF THE INFLUENCE OF AGROECOLOGICAL CONDITIONS AND MINERAL FERTILIZERS ON THE PRODUCTIVITY AND QUALITY OF TOMATOES IN THE GREY-BROWN SOILS OF ABSHERON BASED ON MODERN TECHNOLOGIES
Creators: name: Aliyeva, Konul
Publisher: name: Zenodo
Year: 2025
Subjects: agroecology, tomato, productivity, mineral fertilizers, Absheron, soil science, agricultural technology

description: The main purpose of the research is to study the agroecological characteristics of the grey-brown soils of Absheron based on modern methods and instruments, to map the peninsula using satellite imagery based on GIS, to increase the productivity of the sort of tomato “Ilkin” and obtain a quality product in accordance with local soil and climatic conditions, by introducing optimal norms of fertilizers in the conditions of Absheron in order to ensure food security. The following tasks were performed to achieve the objectives of the research:

Drawing up of a route map for field research on the basis of map-fund materials in the territory of the Absheron Peninsula; Conducting soil research at selected reference points of the peninsula, taking soil samples from genetic layers along the soil profile and studying the agroecological characteristics of soils, compiling sections that characterize the area in accurate geographical coordinates based on GPS; Determination of humus, nitrogen, phosphorus, potassium, pH,Nelectrical conductivity, dry residue, absorbed bases, hygroscopic moisture, carbonate, macro- and microelement content and granulometric composition in soil samples taken; Compilation of Digital Elevation Model map, Land Surface Temperature maps and Normalized Difference Vegetation Index map of Absheron Peninsula using satellite images and multispectral images with the most modern calculations and methods GIS-based; Study of agrochemical and physicochemical properties, microelement and mineralogical composition soils under vegetable in the field of experiment; Research of the effect of fertilization under the tomato plant on the dynamics of the amount of nutrients accumulated in the soil and in the plant; Research of the effect of different norms of urea and ammonium nitrate fertilizers on the productivity and quality of tomato plants on the background of 10 t/ha manure + P90K90; Determination of the economic efficiency of the use of fertilizers for tomatoes in the conditions of Absheron.
3451200.pdf
Creators: name: Pfeiffer, Martin
name: Liu, Junqiu
name: Raja, Arslan
name: Morais, Tiago
name: Ghadiani, Bahareh
name: Kippenberg, Tobias
Publisher: name: Optica Publishing Group
Year: 2018
Subjects: Uncategorized

description: Document containing supplementary information to the manuscript
Design of asynchronous sequential circuits with asynchronous unit delays.
Creators: name: Singh, Shanker.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1968
Subjects: subject: Engineering, Electronics and Electrical.

description: An asynchronous unit delay is an n-input n-output sequential circuit in which the present value of the output n-tuple is equal to the value of the input n-tuple prior to the last input change. This thesis considers the problem of realization of the asynchronous unit delay and its use in the design of asynchronous circuits. Asynchronous fundamental mode flow tables have been classified as "asynchronous definite" and "asynchronous indefinite", where asynchronous definite and asynchronous indefinite properties are modifications of the definite and indefinite properties of synchronous sequential machines respectively. It is shown that a fundamental mode table is realizable as a feedback-free connection of asynchronous unit delays if and only if the table is asynchronous definite. Straight-forward methods of realizing asynchronous definite and asynchronous indefinite flow tables without critical races by circuits of asynchronous unit delays and combinational gates are developed. The use of asynchronous unit delays avoids complicated secondary assignment problems, results in circuits with very simple structure and brings closer the theories of synchronous and asynchronous sequential machines.
Beta-hemolytic Streptococcus dysgalactiae strains isolated from horses are a genetically distinct population within the Streptococcus dysgalactiae taxon
Creators: name: Pinho, Marcos D.
name: Erol, Erdal
name: Ribeiro-Goncalves, Bruno
name: Mendes, Catarina I.
name: Carrico, Joao A.
name: Matos, Sandra C.
name: Luebke-Becker, Antina
name: Wieler, Lothar H.
name: Melo-Cristino, Jose
name: Ramirez, Mario
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie

description: The pathogenic role of beta-hemolytic Streptococcus dysgalactiae in the equine host is increasingly recognized. A collection of 108 Lancefield group C (n = 96) or L (n = 12) horse isolates recovered in the United States and in three European countries presented multilocus sequence typing (MLST) alleles, sequence types and emm types (only 56% of the isolates could be emm typed) that were, with few exceptions, distinct from those previously found in human Streptococcus dysgalactiae subsp. equisimilis. Characterization of a subset of horse isolates by multilocus sequence analysis (MLSA) and 16S rRNA gene sequence showed that most equine isolates could also be differentiated from S. dysgalactiae strains from other animal species, supporting the existence of a horse specific genomovar. Draft genome information confirms the distinctiveness of the horse genomovar and indicates the presence of potentially horse-specific virulence factors. While this genomovar represents most of the isolates recovered from horses, a smaller MLST and MLSA defined sub-population seems to be able to cause infections in horses, other animals and humans, indicating that transmission between hosts of strains belonging to this group may occur.
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation
Creators: name: Hartmann, Luise
name: Dutta, Sayantanee
name: Opatz, Sabrina
name: Vosberg, Sebastian
name: Reiter, Katrin
name: Leubolt, Georg
name: Metzeler, Klaus H.
name: Herold, Tobias
name: Bamopoulos, Stefanos A.
name: Bräundl, Kathrin
name: Zellmeier, Evelyn
name: Ksienzyk, Bianka
name: Konstandin, Nikola P.
name: Schneider, Stephanie
name: Hopfner, Karl-Peter
name: Graf, Alexander
name: Krebs, Stefan
name: Blum, Helmut
name: Middeke, Jan Moritz
name: Stölzel, Friedrich
name: Thiede, Christian
name: Wolf, Stephan
name: Bohlander, Stefan K.
name: Preiss, Caroline
name: Chen-Wichmann, Linping
name: Wichmann, Christian
name: Sauerland, Maria Cristina
name: Büchner, Thomas
name: Berdel, Wolfgang E.
name: Wörmann, Bernhard J.
name: Braess, Jan
name: Hiddemann, Wolfgang
name: Spiekermann, Karsten
name: Greif, Philipp A.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Biological sciences
subject: FOS: Biological sciences
subject: Cancer
subject: Genetics
subject: Molecular biology
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The t(8;21) translocation is one of the most frequent cytogenetic abnormalities in acute myeloid leukaemia (AML) and results in the RUNX1/RUNX1T1 rearrangement. Despite the causative role of the RUNX1/RUNX1T1 fusion gene in leukaemia initiation, additional genetic lesions are required for disease development. Here we identify recurring ZBTB7A mutations in 23% (13/56) of AML t(8;21) patients, including missense and truncating mutations resulting in alteration or loss of the C-terminal zinc-finger domain of ZBTB7A. The transcription factor ZBTB7A is important for haematopoietic lineage fate decisions and for regulation of glycolysis. On a functional level, we show that ZBTB7A mutations disrupt the transcriptional repressor potential and the anti-proliferative effect of ZBTB7A. The specific association of ZBTB7A mutations with t(8;21) rearranged AML points towards leukaemogenic cooperativity between mutant ZBTB7A and the RUNX1/RUNX1T1 fusion.
Auftreten und Vermeidung von Komplikationen bei elektrophysiologischen Eingriffen: Fokus auf besonders gefährdete Patientengruppen und Reduktion von Röntgenstrahlung
Creators: name: Attanasio, Philipp
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: catheter ablation
subject: cardiac device implantation
subject: complications
subject: radiation dose
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Das Ziel dieser Arbeit war die Effektivität und Sicherheit elektrophysiologischer Eingriffe bei Patientengruppen zu untersuchen, die einem besonderen Komplikationsrisiko unterliegen. Außerdem sollten Strategien entwickelt werden, um mögliche Komplikationen zu vermeiden. Die Schwerpunkte der vorgelegten Arbeiten waren: I. Untersuchung der Sicherheit und Effektivität der Eingriffe bei Patienten in höherem Alter II. Untersuchung der Sicherheit und Effektivität der Eingriffe bei Patienten mit einem BMI >30 kg/m². III Reduktion der Strahlendosis ohne Gefährdung der Sicherheit und Effektivität der Prozeduren
description: This habilitation thesis investigates the safety and efficacy of electrophysiological procedures in patient groups that are at a higher risk for complications. It also includes strategies to avoid these complications. Main focus was on: I. Investigating safety and efficacy of electrophysiological procedures in elderly patients. II. Investigating safety and efficacy of electrophysiological procedures in patients with a BMI >30 kg/m². III. Reducing radiation dose without compromising safety and efficacy of these procedures.
Phase equilibria of non-ideal solutions.
Creators: name: Chang, Shinn-Der.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1968
Subjects: subject: Engineering, Chemical.

description: In this investigation new and more efficient means for obtaining, processing and screening the urgently needed vapor-liquid equilibrium data were proposed. Experimental vapor-liquid equilibrium data for the binary and ternary mixtures of the components nitrogen, methane and ethane were obtained at -240°F by means of a modified forced recirculation apparatus. Liquid-liquid-vapor equilibrium data of the ternary system were also obtained at the same temperature. Two methods were proposed for computing vapor phase compositions from total pressure and liquid composition data. One was for low and medium pressure conditions, in which a hypothetical component concept was employed and thus extended the method for binary systems to ternary systems at isothermal condition. The proposed method was successfully applied to the ternary system nitrogen-argon-oxygen. The other was proposed for high pressure systems in which an adjusted activity coefficient was introduced in conjunction with the appropriate symmetric and unsymmetric conventions. As a result, the indirect method was generalized and extended to the high pressure and multicomponent systems. Moreover a nonlinear regression technique was introduced making possible the evaluation of the adjustable parameters. Three binary systems were used to illustrate the proposed method with good results. A general thermodynamic consistency test method which permits a point-by-point evaluation of the vapor-liquid equilibrium data was proposed and the maximum experimental error bounds were also established analytically. Vapor-liquid equilibrium data of one ternary and five binary systems were effectively evaluated by the proposed method. In addition, the total pressure method of Barker was generalized, the composition resolution method of Van Ness was extended to the ternary systems and a five-junction copper-constantan thermopile was built and its calibration table was also prepared.
ROTOR NOISE-AWARE NOISE COVARIANCE MATRIX ESTIMATION FOR UNMANNED AERIAL VEHICLE AUDITION
Creators: Yameizhen Li
Yusuke Hioka
Publisher: name: IEEE Signal Processing Society
Year: 2024

description: A noise covariance matrix (NCM) estimation method for unmanned aerial vehicle (UAV) audition is proposed with rotor noise reduction as its primary focus. The proposed NCM estimation method could be incorporated into audio processing algorithms using UAV-mounted microphone array systems. The NCM is formed through accurate estimation of the microphone array input signal's amplitude and phase by using a multi-sensory rotor noise power spectral density (PSD) estimator and a filter formed by exploiting the acoustical relationship between the microphone array and the rotor noise sources, respectively. The estimated NCM aims to be readily incorporable into several source enhancement algorithms to reduce the effects of rotor noise and improve the resultant audio quality. Experiment evaluation using real in-flight UAV rotor noise recordings shows that the estimated NCM significantly improves rotor noise reduction (of up to ~28dB) and the quality of the target sound.
Human cytomegalovirus interactions with human fibroblast cells: Characterization of a neutralization epitope and identification of cell signalling events.
Creators: name: Haun, Mathias.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Biology, Cell.

description: Human cytomegalovirus (HCMV) hyperimmune globulins or intravenous immunoglobulin (IVIG) have been widely used as a means of passive immunoprophylaxis. The efficacy of these blood products has not been clearly demonstrated in terms of the correlation between anti-HCMV titres assayed by enzyme-linked immunoassay (ELISA) and viral neutralizing activity measured in vitro by plaque reduction assay. Recent advances in the characterization of HCMV surface glycoproteins have led to the identification of the immunodominant regions of these molecules. The mouse monoclonal anti-HCMV antibody CMVB1 was utilized to study the properties of a neutralization epitope. Chemical cross-linking experiments with a photoactivable, heterobifunctional and cleavable reagent identified a viral antigen with an apparent molecular weight of approximately 70 kDa. Microtitre plate binding assays verified that the epitope was unique to HCMV and not homologous to herpesvirus-1 or -2 (HSV-1, -2) antigenic sites. The lectin concanavalin A was found to partially block CMVB1 from binding to the viral epitope, suggesting that carbohydrate moieties may be part of the antigen. Lectin specific sugars such as D-glucose, D-mannose and N-acetylglucosamine did not block CMVB1 binding to HCMV. Cell signalling events induced by HCMV particle binding to human foreskin fibroblast cells were also examined. Central molecules involved in three major signal transduction pathways were studied. Tyrosine phosphorylation was investigated with immunoprecipitation and immunoblotting techniques. Intracellular cyclic adenosine monophosphate (cAMP) concentrations were measured by immunoassay and protein kinase C (PKC) activation was established by a peptide radiolabelling assay. With the methodologies utilized, no evidence of HCMV-induced tyrosine phosphorylation or elevated cAMP concentrations was detected. PKC activity was found to increase to levels typically observed in activated cells. (Abstract shortened by UMI.)
Le début d'application de la loi.
Creators: name: Tremblay, Richard.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1996
Subjects: subject: Law.

description: A la base de la question du debut d'application de la loi se situe la force imperative de la loi: la loi oblige d'Administration comme les citoyens. Cependant, les devoirs decoulant de la loi ne s'imposent pas exactement de la meme maniere a l'un et a l'autre, en particulier sur le plan de son application temporelle. La force imperative se subdivise en deux autres: la force executoire et la force obligatoire. La premiere consiste en un ordre taclte donne par le Parlement aux composantes subalternes de l'Etat, a savoir l'Executif et les tribunaux, de veiller a la mise a execution de la loi. La seconde est l'ordre tacite d'obeissance adresse aux citoyens. Concretement, la force executoire se traduit par l'obligation, pour l'Administration, de mettre en place la structure normative et la structure administrative propres a assurer la pleine effectivite de la loi des la date prevue pour son entree en vigueur. Contrairement a la force executoire, qui est toujours mise en oeuvre a compter de l'ediction de la loi, du moins partiellement, la force obligatoire peut debuter a tout moment: soit a la date meme de la sanction, soit a une date posterieure a la sanction, soit a une date anterieure a la sanction. Voila les trois seuls modes possibles d'entree en vigueur de la loi. (Abstract shortened by UMI.)
Moduli of representations of tame algebras
Creators: name: Gilbert, Cody
Publisher: name: University of Iowa
Year: 2023
Subjects: public abstract

description: In the first chapter, we prove irreducible components of moduli spacesof semistable representations of skewed-gentle algebras, and more generally,
description: clannish algebras, are isomorphic to products of projective spaces. This is achieved by showing irreducible components of varieties of representations of clannish algebras can be viewed as irreducible components of skewed-gentle algebras, which we show are always normal. The main theorem generalizes an analogous result for moduli of representations of special biserial algebras proven by Carroll-Chindris-Kinser-Weyman.
description: The second chapter concerns stability functions for Dynkin quivers, in the generality introduced by Rudakov. We show that relatively few inequalities
description: need to be satisfied for a stability function to be totally stable (i.e. to make every indecomposable stable). Namely, a stability function µ is totally stable if and only if µ(τV ) < µ(V ) for every almost split sequences 0 → τV → E →V → 0 where E is indecomposable. These can be visualized as those sequences around the “border” of the Auslander-Reiten quiver.
Multiplicity of glutamic acid decarboxylase genes: Molecular evolution and steroidal regulation.
Creators: name: Larivière, Katherine.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Biology, Molecular.

description: Gamma-aminobutyric acid (GABA) is a key neurotransmitter for reproductive control. A major site for the control of GABA synthesis is the regulation of synthesis and activity of glutamic acid decarboxylase (GAD), which exists in three isoforms in goldfish. Previous sequence data suggested that GAD65 and GAD67 originated prior to teleost divergence. We have shown that this event occurred prior to 450 million years ago, before the emergence of Chondrichthyes. Previous data showed that estradiol and testosterone modulate GAD65 and GAD67 mRNA levels in sexually regressed goldfish brain. No previous data are available on the regulation of GAD3 in any animal. We found that levels of all three GADS vary seasonally. Steroid administration of testosterone, progesterone and estradiol had seasonal, brain-region and sex specific effects. This is the first evidence for seasonal variations in GAD3 and we show a likely role for progesterone in down-regulating GAD 65 and GAD67 in goldfish brain.
Nonmedical prescription opioid use and illegal drug use: initiation trajectory and related risks among people who use illegal drugs in Vancouver, Canada
Creators: name: Cheng, Tessa
name: Small, Will
name: Nosova, Ekaterina
name: Hogg, Robert S.
name: Hayashi, Kanna
name: Kerr, Thomas
name: DeBeck, Kora
Publisher: name: BioMed Central
Year: 2018

description: Objective: We investigated the prevalence of and risk factors associated with initiating nonmedical prescription opioid use (NMPOU) before and after illegal drugs using data from two linked cohort studies of street youth and adults who use illegal drugs in Vancouver, Canada. All participants who attended a study visit between 2013 and 2016 were eligible for the primary analyses. Results: Among 512 youth and 833 adult participants, the prevalence of NMPOU was extremely high (88% among street youth; 90% among adults), and over one-third of those who reported engaging in NMPOU had initiated NMPOU before illegal drug use (vs. transitioning from illegal drugs to NMPOU). Participants who reported either transitioning to or from NMPOU had higher risk profiles, particularly related to substance use, when compared with those who reported never engaging in NMPOU. Sub-analyses restricted to only those who engaged in NMPOU found few statistically significant differences between those who initiated NMPOU prior to illegal drugs versus those who initiated illegal drugs prior to NMPOU. Findings suggest that among people who use illegal drugs, early NMPOU trajectories do not appear to critically shape future patterns and practices.
Fostering collaborative learning through socially shared regulation prompts
Creators: name: Ham, Yeajin
Publisher: name: University of Iowa
Year: 2025
Subjects: collaborative learning
epistemic action
socially shared regulation of learning
public abstract

description: Collaborative learning presents learners with opportunities to construct knowledge that they may not be able to construct alone. These opportunities are reflected in learners' epistemic actions during collaborative learning, such as explaining concepts, discussing disagreements, and planning, monitoring, and evaluating the group's work. However, learners may hesitate to take epistemic actions due to the challenges they face, such as differing perspectives and understanding among group members, reluctance to externalize thoughts, and domination by one member. To address these challenges, learning environments must provide scaffolds for socially shared regulation of learning (SSRL), which activates regulatory processes to increase learners' awareness of and visibility into their learning processes.
description: In this study, I postulated that learners' epistemic actions could be the intermediate mechanism explaining how scaffolds for SSRL support the learning processes and outcomes. To test this hypothesis, I provided prompts for SSRL to two of the four sections in a science education methods course, while the other two sections did not receive the prompts. The comparison between the intervention and control groups was based on the patterns of epistemic actions as the intermediate process and learning outcomes, including group performance and individual achievement. The analysis showed that the students in the intervention group enacted more regulatory epistemic actions but fewer knowledge-related epistemic actions. Additionally, in the student groups that received the SSRL intervention, students enacted knowledge-related epistemic actions more equally and regulatory epistemic actions less equally. The student groups that received the SSRL intervention outperformed the control group in group performance, but the difference in individual achievement was not significant.
description: The study provides insights into the role of SSRL in collaborative learning and the mechanism through which scaffolds for SSRL support collaborative learning processes and outcomes. The findings have implications for instructional designers in designing regulatory scaffolds in collaborative learning environments and for future research on collaborative learning and the role of SSRL in collaborative learning.
3494038.pdf
Creators: name: Mennea, Paolo
name: clements, william
name: Smith, Devin
name: Gates, James
name: metcalf, ben
name: Bannerman, Rex
name: Burgwal, Roel
name: Renema, Jelmer
name: Kolthammer, W
name: Walmsley, Ian
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary material
Improving state exploration techniques for the automatic verification of concurrent systems.
Creators: name: Van Der Schoot, Johannes J. M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Computer Science.

description: The research underlying this thesis concerns the verification of concurrent systems. In particular, strategies are studied to tackle the state explosion problem which arises during the verification of concurrent systems by state space exploration. State (space) exploration, commonly known also as reachability analysis, amounts to exploring in a systematic manner the entire state space of a system. One of the main causes of the state explosion problem in the verification of concurrent systems is the modeling of concurrency by the exploration of all possible interleavings of concurrent events/transitions. During reachability analysis, each possible way in which the execution of concurrent transitions can be ordered in time is examined. Several of the strategies proposed to relieve the state explosion problem in the verification of concurrent systems have proved promising indeed. This thesis contributes by proposing improvements of three existing relief strategies, namely fair reachability analysis, simultaneous reachability analysis and partial-order reduction methods. First, the technique of fair reachability analysis (FRA) is generalized from cyclic protocols to multi-cyclic protocols modeled as networks of communicating finite state machines (CFSMs). FRA is established as an effective and efficient relief strategy for the detection of deadlocks in multi-cyclic protocols with a finite fair reachable state space. It is also shown that FRA is infeasible as a relief strategy beyond the class of multi-cyclic protocols. Secondly, a technique called leaping reachability analysis (LRA) is presented as an incremental improvement of simultaneous reachability analysis (SRA), which was proposed as a relief strategy for the verification of logical correctness properties of protocols specified in the CFSM model without topological or structural constraints. LRA is proven to maintain the power of SRA to detect all deadlocks, all non-executable transitions, all unspecified receptions and all buffer overflows of the protocol. These analytical results are complemented by an empirical evaluation of the performance of LRA and SRA. Lastly, an enhancement of partial-order reduction methods is proposed for linear-time temporal logic (LTL) model-checking. More precisely, the concepts underlying LRA are integrated with those underlying partial-order reduction methods to enable further savings in both space and time for the verification of linear-time temporal properties of general, finite-state concurrent systems. This approach is subsequently fine-tuned for protocols specified in the CFSM model. (Abstract shortened by UMI.)
Demographic and psychosocial components of health behaviour clusters in Canadian military males.
Creators: name: Moloughney, Brent Ward Patrick.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Biology, Biostatistics.

description: This study explored the inter-relationships between health behaviours and their association with demographic and psychosocial measures in a population of Canadian military males. The objectives of this thesis were to determine first, whether health behaviours are independent of each other and if not, second, whether their inter-relationships vary (i) based upon the manner in which the health behaviours are scored; and (ii) between demographic sub-groups. The third objective was to determine whether the association between health behaviour clusters and psychosocial measures varied for different clusters of behaviours. Additional analyses were performed exploring the relationship between health behaviours and health status. While individuals reporting excellent health status performed on average twice as many health behaviours at a positive level compared to those reporting poor health, substantial variability in the relationship was observed. This is a reminder that there are many factors other than personal behaviours which influence health status. (Abstract shortened by UMI.)
Improving Remote Health Monitoring: A Low-Complexity ECG Compression Approach
Creators: name: Elgendi, Mohamed
name: Al-Ali, Abdulla
name: Mohamed, Amr
name: Ward, Rabab Kreidieh
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Recent advances in mobile technology have created a shift towards using battery-driven devices in remote monitoring settings and smart homes. Clinicians are carrying out diagnostic and screening procedures based on the electrocardiogram (ECG) signals collected remotely for outpatients who need continuous monitoring. High-speed transmission and analysis of large recorded ECG signals are essential, especially with the increased use of battery-powered devices. Exploring low-power alternative compression methodologies that have high efficiency and that enable ECG signal collection, transmission, and analysis in a smart home or remote location is required. Compression algorithms based on adaptive linear predictors and decimation by a factor B / K are evaluated based on compression ratio (CR), percentage root-mean-square difference (PRD), and heartbeat detection accuracy of the reconstructed ECG signal. With two databases (153 subjects), the new algorithm demonstrates the highest compression performance ( CR = 6 and PRD = 1.88 ) and overall detection accuracy (99.90% sensitivity, 99.56% positive predictivity) over both databases. The proposed algorithm presents an advantage for the real-time transmission of ECG signals using a faster and more efficient method, which meets the growing demand for more efficient remote health monitoring.
Strength through sharing: Mi'kmaq political thought to 1761
Creators: name: Leech, David J
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Political Science, General.
subject: Native American Studies.

description: We stand witness at the dawn of the 21st century to increasing tensions between Aboriginal people in Canada, and the Canadian state, largely as a result of conflict over natural resources. Do these conflicts imply that we are unable to understand each other? Does the meaning of our words get 'lost in translation' as it crosses the space between us? If this is so, then how can we envision dialogue between the two craft depicted in the Kaswentha, when---from a Canadian perspective---we don't understand the words each of us is using? When we don't understand the meaning of 'sovereignty' from the perspective of an Aboriginal participant in the dialogue, how can we understand what possibilities of cooperation are open to us? The Mi'kmaq, in their own traditions and 'worldview', clearly articulated their own understanding of 'sovereignty' based on their traditions of political thought and action. Through their economic, legal, spiritual, political and 'environmental' articulations, the Mi'kmaq projected their understanding of 'sovereignty' into the creation of relationships with the French, Jesuit and English immigrants which arrived on their shores. Through an analysis of these articulations, we gain a new appreciation for Mi'kmaq sovereignty---one founded on the concept of sharing. The three pillars of continuity, responsibility---for themselves and their 'extended European kin'---and relationship-building characterized this shared space within which the Mi'kmaq founded their relationship with their blue-eyed 'kin'. In all of its aspects---environment and land; spiritual, political and legal; and economic---Mi'kmaq sovereignty was about the paths and passes that allowed them to build relationships with others. Indeed, in its content and structure, Mi'kmaq sovereignty was, and is, shared sovereignty---an idea that opens our minds to a new way of understanding the political landscape of 21st century Mi'kma'ki. Drawing on this concept of shared sovereignty, ideas with respect to the co-management of natural resources are discussed. These ideas draw to a conclusion the thesis, and open avenues for further research and reflection on the place of Aboriginal political thought in the foundations of political culture in Canada.
Study of lanthanum-based cathode materials for organic light-emitting devices.
Creators: name: Gorjanc, Timothy C.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Physics, Condensed Matter.

description: Since the dawn of the information age, the high technology industry has been driven to display more data and to create large area high-resolution displays. Organic light emitting diodes, introduced in the late 1980s, are emerging as an attractive alternative to other display technologies. These devices offer cheap materials, low operating voltages, high brightness and a wide viewing angle. The ability to spin coat molecular materials on large rigid or flexible substrates is unparalleled in existing technologies. Several different device geometries are possible, ranging from the simple homostructure, where there is only one organic material present, to the complex microcavity, where dielectric stacks are used to selectively filter out specific wavelengths of light. No matter which geometry is chosen, all of these devices have several common features: a high work function anode (usually transparent) and a low work function cathode. Due to the low work function requirement of the cathode, we are limited to the very reactive metals in the periodic table. In this thesis cathodes based on pure lanthanum, lanthanum-silver bilayers, and lanthanum-yttrium alloys were investigated. (Abstract shortened by UMI.)
Update of national and international resource use indicators
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2013
Subjects: subject: Ressourcenverbrauch
subject: Kenngröße
subject: Bewertungskriterium
subject: Berechnung
subject: Internationaler Vergleich
subject: Rohstoffnutzung
subject: Rohstoffverbrauch
subject: bioindicator
subject: domestic material consumption
subject: Total Material Requirement (TMR)
subject: Total Material Consumption (TMC)
subject: material amount
subject: Abfall | Ressourcen
subject: Waste | Resources

description: The study “Update of national and international resource use indicators” contains three main parts. In the first part central resource indicators for Germany such as Domestic Material Consumption (DMC) and ⁠Total Material Requirement⁠ (⁠TMR⁠) were updated until 2008. The final part of the study identifies further research questions that will need to be addressed in order to improve the quality of selected indicators of material analysis.
Parent and physician decision making in children with suspected ear infection presenting to a children's hospital emergency department.
Creators: name: Page, Jacqueline.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Health Sciences, Medicine and Surgery.

description: Problem statement. This study examines the parent decision to consult a physician, a physician diagnostic decision and a treatment decision in a common childhood illness, acute otitis media (AOM). Method. Physicians and parents of children with suspected ear infection consulting an emergency department in March--June 1998 were surveyed to describe factors related to parent and physician diagnostic and treatment decisions. Results. Parents consulted the ED when their usual caregiver was unavailable. Thirty-eight percent of 769 children were diagnosed with AOM. Presence of earache, absence of fever, parent suspicion of ear infection, and physician work status were each significantly associated with AOM diagnosis. Antibiotics were prescribed for 78% of AOM children. Presence of earache, fever and physician work status was each significantly associated with a decision to prescribe antibiotics. Conclusion. This study provides information to support the development of a physician-parent guide to the diagnosis and treatment of AOM.
3494038.pdf
Creators: name: Mennea, Paolo
name: clements, william
name: Smith, Devin
name: Gates, James
name: metcalf, ben
name: Bannerman, Rex
name: Burgwal, Roel
name: Renema, Jelmer
name: Kolthammer, W
name: Walmsley, Ian
Publisher: name: Optica Publishing Group
Year: 2018
Subjects: Uncategorized

description: Supplementary material
Formal modeling and test generation automation with Use Case Maps and LOTOS.
Creators: name: Charfi, Leila.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Computer Science.

description: This thesis addresses the problem of formal modelling and test generation, from system requirements represented in the form of Use Case Maps. In the first part of our thesis, we present an existent development methodology based on Use Case Maps for the design of the requirements and on LOTOS and SDL for the formal modeling of telecommunication systems. We follow this methodology for the formal specification and validation of a telephony system using LOTOS. In the second part of the thesis, we develop a method for the automatic generation of LOTOS scenarios from Use Case Maps called Ucm2LotosTests. The obtained scenarios can be used for the verification of the LOTOS specification built from the same Use Case Maps and for conformance testing purposes at the implementation stage. Finally, we propose a development methodology based on Use Case Maps for the design of the requirements and on LOTOS for the formal modeling of the system. In addition, this methodology offers a fast test generation process; it proposes the use of Ucm2LotosTests for the automatic generation of LOTOS scenarios from requirements in UCM and of TGV for the automatic generation of TTCN test suites from LOTOS. The methodology is illustrated with a case study which is a telephony system providing the basic call feature.