cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: of Evidence supporting regulatory-decision making on orphan medicinal products authorisation in Europe: methodological uncertainties
Creators: name: Pontes, Caridad
name: Fontanet, Juan
name: Vives, Roser
name: Aranzazu Sancho
name: Mònica Gómez-Valent
name: Ríos, José
name: Morros, Rosa
name: Martinalbo, Jorge
name: Posch, Martin
name: Koch, Armin
name: Roes, Kit
name: Rengerink, Katrien
name: Torrent-Farnell, Josep
name: Torres, Ferran
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Table S1. Characteristics used to describe the evidence supporting marketing authorization application in European Public Assessment Reports of Orphan Medicinal Products. Table S2. Clustering of the 85 medical conditions in European Public Assessment Reports of Orphan Medicinal Products. Table S3. Dictionary of some methodological terms. Figure S1. Number of European Public Assessment Reports in each cluster. (DOCX 47 kb)
Innovation Oakland: Direction, Information, Destination
Creators: name: Carter, Donald K.
name: Gatti, Elise
name: Brill, Christine
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 120501 Community Planning
subject: FOS: Social and economic geography
subject: 120508 Urban Design

description: Innovation Oakland In 2009, the Remaking Cities Institute developed a community-wide wayfinding infrastructure initiative that celebrates the Oakland community as an international center of new technology and research innovation. Oakland, the educational and medical heart of Pittsburgh, is the third largest business district in Pennsylvania after downtown Philadelphia and downtown Pittsburgh. Innovation Oakland combines technology, design, sustainable practices, and multi-layered community planning in a comprehensive wayfinding system. It highlights Oakland's unique assets while providing critical information such as real time public transportation schedules, parking availability and locations, ZipCar locations and availability, bike rack locations, community events, hospital facilities, museum exhibits, and business locations. The Project Sponsor was the Oakland Task Force(OTF) and the Lead Agency was the Oakland Business and Improvement District (OBID). The Research Team was led by the Remaking Cities Institute, with researchers from the Remaking Cities Institute, School of Design, School of Architecture, Heinz School for Public Policy, CyLab Mobility Research Center and the Entertainment Technology Center (ETC). Funding was provided by Carlow University, Carnegie Mellon University, Oakland Business Improvement District (OBID), University of Pittsburgh, UPMC, the CMU Traffic21 Initiative, and the Richard King Mellon Foundation.
Three-dimensional radiative transfer simulations of the scattering polarization of the hydrogen Ly$α$ line in a MHD model of the chromosphere-corona transition region
Creators: name: Stepan, Jiri
name: Bueno, Javier Trujillo
name: Leenaarts, Jorrit
name: Carlsson, Mats
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Probing the magnetism of the upper solar chromosphere requires measuring and modeling the scattering polarization produced by anisotropic radiation pumping in UV spectral lines. Here we apply PORTA (a novel radiative transfer code) to investigate the hydrogen Ly$α$ line in a 3D model of the solar atmosphere resulting from a state of the art MHD simulation. At full spatial resolution the linear polarization signals are very significant all over the solar disk, with a large fraction of the field of view showing line-center amplitudes well above the 1% level. Via the Hanle effect the line-center polarization signals are sensitive to the magnetic field of the model's transition region, even when its mean field strength is only 15 G. The breaking of the axial symmetry of the radiation field produces significant forward-scattering polarization in Ly$α$, without the need of an inclined magnetic field. Interestingly, the Hanle effect tends to decrease such forward-scattering polarization signals in most of the points of the field of view. When the spatial resolution is degraded, the line-center polarization of Ly$α$ drops below the 1% level, reaching values similar to those previously found in 1D semi-empirical models (i.e., up to about 0.5%). The center to limb variation of the spatially-averaged polarization signals is qualitatively similar to that found in 1D models, with the largest line-center amplitudes at $μ=\cosθ\approx 0.4$ ($θ$ being the heliocentric angle). These results are important, both for designing the needed space-based instrumentation and for a reliable interpretation of future observations of the Ly$α$ polarization.
description: 15 pages, 15 figures, accepted for publication in The Astrophysical Journal
Short Timescale Evolution of the Polarized Radio Jet during V404 Cygni's 2015 Outburst
Creators: name: Hughes, Andrew K.
name: Sivakoff, Gregory R.
name: Macpherson, Christopher E.
name: Miller-Jones, James C. A.
name: Tetarenko, Alexandra J.
name: Altamirano, Diego
name: Anderson, Gemma E.
name: Belloni, Tomaso M.
name: Heinz, Sebastian
name: Jonker, Peter G.
name: Körding, Elmar G.
name: Maitra, Dipankar
name: Markoff, Sera B.
name: Migliari, Simone
name: Mooley, Kunal P.
name: Rupen, Michael P.
name: Russell, David M.
name: Russell, Thomas D.
name: Sarazin, Craig L.
name: Soria, Roberto
name: Tudose, Valeriu
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a high time resolution, multi-frequency linear polarization analysis of Very Large Array (VLA) radio observations during some of the brightest radio flaring (~1 Jy) activity of the 2015 outburst of V404 Cygni. The VLA simultaneously captured the radio evolution in two bands (each with two 1 GHz base-bands), recorded at 5/7 GHz and 21/26 GHz, allowing for a broadband polarimetric analysis. Given the source's high flux densities, we were able to measure polarization on timescales of ~13 minutes, constituting one of the highest temporal resolution radio polarimetric studies of a black hole X-ray binary (BHXB) outburst to date. Across all base-bands, we detect variable, weakly linearly polarized emission (<1%) with a single, bright peak in the time-resolved polarization fraction, consistent with an origin in an evolving, dynamic jet component. We applied two independent polarimetric methods to extract the intrinsic electric vector position angles and rotation measures from the 5 and 7 GHz base-band data and detected a variable intrinsic polarization angle, indicative of a rapidly evolving local environment or a complex magnetic field geometry. Comparisons to the simultaneous, spatially-resolved observations taken with the Very Long Baseline Array at 15.6 GHz, do not show a significant connection between the jet ejections and the polarization state.
description: 24 pages, 9 figures, accepted by MNRAS
THE ECOCENTRIC ENVIRONMENTAL PARADIGM IN COEHLO'S THE ALCHEMIST
Creators: name: Mantha Padmabandhavi Prakashrao
Publisher: name: Zenodo
Year: 2022
Subjects: Ecocentrism, ecosystem, humanity, self-interest and ethics.

description: Abstract:  In the present world’s geographical scenario , the status of environment is a vital issue. Despite the efforts of Government and Ecocentric groups, the question of the environment has remained unchanged. And this exacting key matter has been observed by many scientists, ecologists and writers throughout the world. Paulo Coelho, a Brazilian novelist also dealt with such issues for conserving the nature and its resources. The terms Ecocentrism and Anthropocentrism are like two poles. The philosophy of Ecocentrism regards nature as the centre for man while Anthropocentrism believes in self-centeredness of human. In the Alchemist, the author advocates the Ecocentric values among the readers. One can perceive these ethics in the actions and beliefs of Santiago, a protagonist. Santiago is a shepherd boy and his fondness for the sheep conveys the message of love for the nature and the animals. Paulo Coelho’s perception of Ecocentrism can be explicated when we find Santiago’s growing concern for nature, sea and desert. On his journey to find the treasure, Santiago chance upon many creatures and things on the earth. He begins to observe and learn many things from the animals, things and desert. Coelho, a staunch believer of Ecocentric values, reveals that it is man’s responsibility to save and care for earth and nature. In the Alchemist, the impressions of anthropocentric philosophy can be seen, where man is self-centered. As a human being, the shepherd boy also longs for wealth. In order to fulfill his dreams, he sets out on journey to seek out the treasure. In due course of time, he meets the Alchemist, who gains the wisdom to convert a metal into gold. In The Alchemist, Coelho promotes the message of love and belief in God. Santiago stalks his dreams and pursue till the end. Through the character of Santiago, Coelho illustrates the importance of ecosystem and the ethics of humans on the earth, for creating healthy humans as well as healthy minds on the earth.
Search for supersymmetry at the Large Hadron Collider
Creators: name: Obikhod, T. V.
name: Negliad, V. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Search for supersymmetry is carried out in the framework of the Minimal Supersymmetric Standard Model (MSSM). Using the software programs SOFTSUSY and PROSPINO, the mass spectrum and the production cross-sections of superpartners are calculated. The results obtained are of importance for searching the new physics at the LHC.
description: 11 pages, 2 figures
Reactivity of stabilized Criegee intermediates (sCIs) from isoprene and monoterpene ozonolysis toward SO2 and organic acids
Creators: name: Sipilä, M.
name: Jokinen, T.
name: Berndt, T.
name: Richters, S.
name: Makkonen, R.
name: Donahue, N.M.
name: Mauldin III, R.L.
name: Kurtén, T.
name: Paasonen, P.
name: Sarnela, N.
name: Ehn, M.
name: Junninen, H.
name: Rissanen, M.P.
name: Thornton, J.
name: Stratmann, F.
name: Herrmann, H.
name: Worsnop, D.R.
name: Kulmala, M.
name: Kerminen, V.-M.
name: Petäjä, T.
Publisher: name: München : European Geopyhsical Union
Year: 2014
Subjects: subject: atmospheric chemistry
subject: atmospheric pressure
subject: isoprene
subject: monoterpene
subject: organic acid
subject: sulfur dioxide
subject: sulfuric acid
subject: 550

description: Oxidation processes in Earth's atmosphere are tightly connected to many environmental and human health issues and are essential drivers for biogeochemistry. Until the recent discovery of the atmospheric relevance of the reaction of stabilized Criegee intermediates (sCIs) with SO2, atmospheric oxidation processes were thought to be dominated by a few main oxidants: ozone, hydroxyl radicals (OH), nitrate radicals and, e.g. over oceans, halogen atoms such as chlorine. Here, we report results from laboratory experiments at 293 K and atmospheric pressure focusing on sCI formation from the ozonolysis of isoprene and the most abundant monoterpenes (α-pinene and limonene), and subsequent reactions of the resulting sCIs with SO2 producing sulfuric acid (H2SO4). The measured total sCI yields were (0.15 ± 0.07), (0.27 ± 0.12) and (0.58 ± 0.26) for α-pinene, limonene and isoprene, respectively. The ratio between the rate coefficient for the sCI loss (including thermal decomposition and the reaction with water vapour) and the rate coefficient for the reaction of sCI with SO2, k(loss) /k(sCI + SO2), was determined at relative humidities of 10 and 50%. Observed values represent the average reactivity of all sCIs produced from the individual alkene used in the ozonolysis. For the monoterpene-derived sCIs, the relative rate coefficients k(loss) / k(sCI + SO2) were in the range (2.0–2.4) × 1012 molecules cm−3 and nearly independent of the relative humidity. This fact points to a minor importance of the sCI + H2O reaction in the case of the sCI arising from α-pinene and limonene. For the isoprene sCIs, however, the ratio k(loss) / k(sCI + SO2) was strongly dependent on the relative humidity. To explore whether sCIs could have a more general role in atmospheric oxidation, we investigated as an example the reactivity of acetone oxide (sCI from the ozonolysis of 2,3-dimethyl-2-butene) toward small organic acids, i.e. formic and acetic acid. Acetone oxide was found to react faster with the organic acids than with SO2; k(sCI + acid) / k(sCI + SO2) = (2.8 ± 0.3) for formic acid, and k(sCI + acid) / k(sCI + SO2) = (3.4 ± 0.2) for acetic acid. This finding indicates that sCIs can play a role in the formation and loss of other atmospheric constituents besides SO2.
Are we reasoning about cloud application vulnerabilities in the right way?
Creators: name: Simonetto, Stefano
name: Bosch, Peter
Publisher: name: Zenodo
Year: 2023

description: Abstract: Enterprises are quickly transitioning to container orchestrators, like Kubernetes, which helps developers and engineers manage a large number of container images, pods, and nodes. However, this new approach does not solve the problem of software vulnerabilities but arguably it makes vulnerability management harder. Most of the time, companies have to deal with thousands of containers in a dynamic environment since they can fail, and be rescheduled in other nodes. All these factors have a great impact on the vulnerability management system because the vulnerabilities and misconfigurations in the system are too many to be manually operated, so we seek a tool to highlight the most dangerous (we need a clear definition of dangerous) to prioritize them. This paper wants to emphasize the need for a vulnerability prioritization method and a defense technique improvement.
title: There's something not right with this gallbladder! Lymphoeosinophilic cholecystitis, the other acalculus cholecystitis.
Creators: name: Taylor, Andrew
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2023
Subjects: subject: Abdomen
subject: CT
subject: MR
subject: Surgery
subject: Inflammation

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To describe a case report of lymphoeosinophilic cholecystitis. To demonstrate the imaging findings of lymphoeosinophilic...
CMS Tracker Alignment Activities during LHC Long Shutdown 2
Creators: name: Rodríguez, Sandra Consuegra
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The strategies for and the performance of the CMS tracker alignment during the 2021-2022 LHC commissioning preceding the Run 3 data-taking period are described. The results of the very first tracker alignment after the pixel reinstallation, performed with cosmic ray muons recorded with the solenoid magnet off are presented. Also, the performance of the first alignment of the commissioning period with collision data events, collected at center-of-mass energy of 900 GeV, is presented. Finally, the tracker alignment effort during the final countdown to LHC Run 3 is discussed.
description: on behalf of the CMS Collaboration, 41st International Conference on High Energy physics - ICHEP2022, 6-13 July, 2022
The cross-sectional association of stressful life events with depression severity among patients with hypertension and diabetes in Malawi
Creators: name: Udedi M.
name: Pence B.W.
name: Kulisewa K.
name: Zimba C.C.
name: Hosseinipour M.C.
name: Dussault J.M.
name: Gaynes B.N.
name: Landrum K.R.
name: Malava J.K.
name: Masiye J.
name: Akello H.
Publisher: name: Public Library of Science
Year: 2022

description: Depressive disorders are a leading cause of global morbidity and remain disproportionately high in low- and middle-income settings. Stressful life events (SLEs) are known risk factors for depressive episodes and worsened depressive severity, yet are under-researched in comparison to other depression risk factors. As depression is often comorbid with hypertension, diabetes, and other noncommunicable diseases (NCDs), research into this relationship among patients with NCDs is particularly relevant to increasing opportunities for integrated depression and NCD care. This study aims to estimate the cross-sectional association between SLEs in the three months preceding baseline interviews and baseline depressive severity among patients with at least mild depressive symptoms who are seeking NCD care at 10 NCD clinics across Malawi. SLEs were measured by the Life Events Survey and depressive severity (mild vs. moderate to severe) was measured by the Patient Health Questionnaire-9. The study population (n = 708) was predominately currently employed, grand multiparous (5–8 children) women with a primary education level. Two thirds (63%) had mild depression while 26%, 8%, and 3% had moderate, moderately severe, and severe depression, respectively. Nearly all participants (94%) reported at least one recent SLE, with the most common reported SLEs being financial stress (48%), relationship changes (45%), death of a family member or friend (41%), or serious illness of a family member or friend (39%). Divorce/separation, estrangement from a family member, losing source of income, and major new health problems were significant predictors of greater (moderate or severe) depressive severity compared to mild severity. Having a major new health problem or experiencing divorce/separation resulted in particularly high risk of more severe depression. After adjustment, each additional SLE was associated with a 9% increased risk of moderate or worse depressive severity compared to mild depressive severity (RR: 1.09; (95% CI: 1.05, 1.13), p<0.0001). Among patients with NCDs with at least mild depressive symptoms, SLEs in the prior 3 months were associated with greater depressive severity. While many SLEs may not be preventable, this research suggests that assessment of SLEs and teaching of positive coping strategies when experiencing SLEs may play an important role in integrated NCD and depression treatment models.
Additional file 1 of Exosomes in the pathogenesis and treatment of cancer-related cachexia
Creators: name: Ru, Qin
name: Chen, Lin
name: Xu, Guodong
name: Wu, Yuxiang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
Detection and imaging of the oxygen deficiency in single crystalline YBa$_{\text{2}}$Cu$_{\text{3}}$O$_{\text{7}-δ}$ thin films using a positron beam
Creators: name: Reiner, Markus
name: Gigl, Thomas
name: Jany, Rainer
name: Hammerl, German
name: Hugenschmidt, Christoph
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Single crystalline YBa$_{\text{2}}$Cu$_{\text{3}}$O$_{\text{7}-δ}$ (YBCO) thin films were grown by pulsed laser deposition (PLD) in order to probe the oxygen deficiency $δ$ using a mono-energetic positron beam. The sample set covered a large range of $δ$ (0.191
Additional file 2 of Exosomes in the pathogenesis and treatment of cancer-related cachexia
Creators: name: Ru, Qin
name: Chen, Lin
name: Xu, Guodong
name: Wu, Yuxiang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Supplementary Material 2
MPEC 2023-R05 : 2014 SQ143
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: CNS manifestations of Tuberous Sclerosis: Pictorial Review.
Creators: name: Taylor, Andrew
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2023
Subjects: subject: Neuroradiology brain
subject: MR
subject: Education
subject: Other

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To provide a pictorial review of the radiological signs associated with Tuberous Sclerosis in the CNS To provide an overview of Tuberous...
The enterovirus genome can be translated in an IRES-independent manner that requires the initiation factors eIF2A/eIF2D
Creators: name: Kim, Hyejeong
name: Shengjuler, Djoshkun
name: Sotoudegan, Mohamad S.
name: Arnold, Jamie J.
name: Aponte-Diaz, David
name: Cameron, Craig E.
Publisher: name: Public Library of Science
Year: 2023

description: RNA recombination in positive-strand RNA viruses is a molecular-genetic process, which permits the greatest evolution of the genome and may be essential to stabilizing the genome from the deleterious consequences of accumulated mutations. Enteroviruses represent a useful system to elucidate the details of this process. On the biochemical level, it is known that RNA recombination is catalyzed by the viral RNA-dependent RNA polymerase using a template-switching mechanism. For this mechanism to function in cells, the recombining genomes must be located in the same subcellular compartment. How a viral genome is trafficked to the site of genome replication and recombination, which is membrane associated and isolated from the cytoplasm, is not known. We hypothesized that genome translation was essential for colocalization of genomes for recombination. We show that complete inactivation of internal ribosome entry site (IRES)-mediated translation of a donor enteroviral genome enhanced recombination instead of impairing it. Recombination did not occur by a nonreplicative mechanism. Rather, sufficient translation of the nonstructural region of the genome occurred to support subsequent steps required for recombination. The noncanonical translation initiation factors, eIF2A and eIF2D, were required for IRES-independent translation. Our results support an eIF2A/eIF2D-dependent mechanism under conditions in which the eIF2-dependent mechanism is inactive. Detection of an IRES-independent mechanism for translation of the enterovirus genome provides an explanation for a variety of debated observations, including nonreplicative recombination and persistence of enteroviral RNA lacking an IRES. The existence of an eIF2A/eIF2D-dependent mechanism in enteroviruses predicts the existence of similar mechanisms in other viruses.
Multivariate Classification with Random Forests for Gravitational Wave Searches of Black Hole Binary Coalescence
Creators: name: Baker, Paul T.
name: Caudill, Sarah
name: Hodge, Kari A.
name: Talukder, Dipongkar
name: Capano, Collin
name: Cornish, Neil J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Searches for gravitational waves produced by coalescing black hole binaries with total masses $\gtrsim25\,$M$_\odot$ use matched filtering with templates of short duration. Non-Gaussian noise bursts in gravitational wave detector data can mimic short signals and limit the sensitivity of these searches. Previous searches have relied on empirically designed statistics incorporating signal-to-noise ratio and signal-based vetoes to separate gravitational wave candidates from noise candidates. We report on sensitivity improvements achieved using a multivariate candidate ranking statistic derived from a supervised machine learning algorithm. We apply the random forest of bagged decision trees technique to two separate searches in the high mass $\left( \gtrsim25\,\mathrm{M}_\odot \right)$ parameter space. For a search which is sensitive to gravitational waves from the inspiral, merger, and ringdown (IMR) of binary black holes with total mass between $25\,$M$_\odot$ and $100\,$M$_\odot$, we find sensitive volume improvements as high as $70_{\pm 13}-109_{\pm 11}$\% when compared to the previously used ranking statistic. For a ringdown-only search which is sensitive to gravitational waves from the resultant perturbed intermediate mass black hole with mass roughly between $10\,$M$_\odot$ and $600\,$M$_\odot$, we find sensitive volume improvements as high as $61_{\pm 4}-241_{\pm 12}$\% when compared to the previously used ranking statistic. We also report how sensitivity improvements can differ depending on mass regime, mass ratio, and available data quality information. Finally, we describe the techniques used to tune and train the random forest classifier that can be generalized to its use in other searches for gravitational waves.
Intercomparison of air ion spectrometers: An evaluation of results in varying conditions
Creators: name: Gagné, S.
name: Lehtipalo, K.
name: Manninen, H.E.
name: Nieminen, T.
name: Schobesberger, S.
name: Franchin, A.
name: Yli-Juuti, T.
name: Boulon, J.
name: Sonntag, A.
name: Mirme, S.
name: Mirme, A.
name: Hõrrak, U.
name: Petäjä, T.
name: Asmi, E.
name: Kulmala, M.
Publisher: name: München : European Geopyhsical Union
Year: 2011
Subjects: subject: comparative study
subject: data processing
subject: growth rate
subject: guideline
subject: ion
subject: size distribution
subject: spectrometer
subject: 550

description: We evaluated 11 air ion spectrometers from Airel Ltd. after they had spent one year in field measurements as a part of the EUCAARI project: 5 Air Ion Spectrometers (AIS), 5 Neutral cluster and Air Ion Spectrometers (NAIS) and one Airborne NAIS (ANAIS). This is the first time that an ANAIS is evaluated and compared so extensively. The ion spectrometers' mobility and concentration accuracy was evaluated. Their measurements of ambient air were compared between themselves and to reference instruments: a Differential Mobility Particle Sizer (DMPS), a Balanced Scanning Mobility Analyzer (BSMA), and an Ion-DMPS. We report on the simultaneous measurement of a new particle formation (NPF) event by all 11 instruments and the 3 reference instruments. To our knowledge, it is the first time that the size distribution of ions and particles is measured by so many ion spectrometers during a NPF event. The new particle formation rates (~0.2 cm−3 s−1 for ions and ~2 cm−3 s−1 for particles) and growth rates (~25 nm h−1 in the 3–7 nm size range) were calculated for all the instruments. The NAISs and the ANAIS gave higher concentrations and formation rates than the AISs. For example, the AISs agreed with the BSMA within 11 % and 28 % for negative and positive ion concentration respectively, whereas the NAISs agreed within 23 % and 29 %. Finally, based on the results presented here, we give guidelines for data evaluation, when data from different individual ion spectrometers are compared.
Don't Trust, Verify: Empowering Last-Mile Security and Privacy in Web3
Creators: name: Weihong Wang
name: Van Cutsem, Tom
Publisher: name: Zenodo
Year: 2023

description: Abstract: The bridging of Web2 and Web3 infrastructure is a crucial step towards a fully decentralized internet. However, participating in blockchain systems can be a significant barrier for most users due to factors such as the high cost of operation and the computational resources required. To interact with the blockchain, Web3 application builders rely on endpoint API services, which can cause centralization issues in terms of privacy, availability, and security. In response, the community has turned to light nodes as a potential solution for resource-constrained clients such as smartphones and browsers to facilitate involvement. In this paper, we provide an overview of recent studies in light nodes, along with an analysis of light client implementations in Ethereum and their improvements. We conclude with a call for further development of light node technology to enable broader and more diverse participation in decentralized systems.
Therapeutic efficacy of Chloroquine for the treatment of uncomplicated Plasmodium vivax infection in Shewa Robit, Northeast Ethiopia
Creators: name: Gidey B.
name: Tamene A.A.
name: Assefa G.
name: Reta M.A.
name: Haile M.
name: Tasew G.
name: Sime H.
name: Bekele W.
name: Hailu T.
name: Belay H.
name: Alemu M.
name: Assefa A.
name: Hailegeorgies H.
name: Mohammed H.
Publisher: name: Public Library of Science
Year: 2023

description: Background The development of drug resistance to chloroquine is posing a challenge in the prevention and control efforts of malaria globally. Chloroquine is the first-line treatment for uncomplicated P.vivax in Ethiopia. Regular monitoring of anti-malarial drugs is recommended to help early detection of drug-resistant strains of malaria parasites before widely distributed. The emergence of P.vivax resistance to chloroquine in the country endangers the efficacy of P. vivax treatment. This study aimed to assess the therapeutic efficacy of chloroquine among uncomplicated P.vivax infections at Shewa Robit Health Center, northeast Ethiopia. Methods One-arm in vivo prospective chloroquine efficacy study was conducted from November 2020 to March 2021. Ninety participants aged between 16 months to 60 years confirmed with P.vivax mono-infection microscopically were selected and treated with a 25 mg/kg standard dose of chloroquine over three days. Thick and thin blood smears were prepared and examined. Clinical examination was performed over 28 follow-up days. Hemoglobin concentration level was measured on days 0, 14, and 28. Result Of the 90 enrolled participants, 86 (96%) completed their 28 days follow-up period. The overall cure rate of the drug was 98.8% (95% CI: 95.3-100%). All asexual stages and gametocytes were cleared within 48 hours with rapid clearance of fever. Hemoglobin concentration had significantly recovered between days 0 and 14, 0 and 28, and 14 and 28 days (P = 0.032, P<0.001, and P = 0.005), respectively. Fast resolution of clinical signs and symptoms was also observed. Severe adverse events were not recorded. Conclusion The present study revealed that chloroquine remains an efficacious and safe drug in the study setting for treating uncomplicated P.vivax in the study area. Large-scale continuous surveillance is needed to monitor the development of resistance in due time.
Additional file 1 of Targeting interleukin-6 as a treatment approach for peritoneal carcinomatosis
Creators: name: Dadgar, Neda
name: Sherry, Christopher
name: Zimmerman, Jenna
name: Park, Hyun
name: Lewis, Catherine
name: Donnenberg, Albert
name: Zaidi, Ali H.
name: Fan, Yong
name: Xiao, Kunhong
name: Bartlett, David
name: Donnenberg, Vera
name: Wagner, Patrick L.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
title: Don't shout at me!
Creators: name: Man, Ralph Xiu-Gee
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2023
Subjects: subject: Interventional non-vascular
subject: Other
subject: Biopsy
subject: Education
subject: Education and training

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To explore techniques to improve communication between the trainee inside and the supervising interventionalist outside of the procedure room using new...
On the algebraic structure of rational discrete dynamical systems
Creators: name: Viallet, Claude M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Algebraic Geometry (math.AG)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We show how singularities shape the evolution of rational discrete dynamical systems. The stabilisation of the form of the iterates suggests a description providing among other things generalised Hirota form, exact evaluation of the algebraic entropy as well as remarkable polynomial factorisation properties. We illustrate the phenomenon explicitly with examples covering a wide range of models.
Using Causal Inference to Extract Hidden Information from Dependency Modelling
Creators: name: Ayodeji Rotibi
name: Neetesh Saxena
name: Burnap, Pete
Publisher: name: Zenodo
Year: 2023

description: Abstract: Dependency Modelling is an established Probabilistic Risk Analysis method that is frequently used to identify and quantify cyber risks in complex environments, such as Industrial Control Systems. The method is useful for examining the interrelationships between different variables, but the limited data exposure in the modelling restricts its ability to analyse multiple independent variables simultaneously or sequentially. In response to this limitation, we present a new technique that leverages the Bayesian Network method to draw inferences from unrelated events and uncovers hidden insights that Dependency Modelling may overlook. We conducted an evaluation of our proposed technique using lab-generated data that mimics Colonial pipeline operations. Our results demonstrated that the proposed technique exposes previously undetected aspects of the dependency model, providing business and asset owners with a more comprehensive understanding of their cyber risks and facilitating better decision making. Our technique represents a significant advancement and is the first to apply this inference method to Dependency Modelling.
Writings of resistance
Creators: name: Levy, Deena Ruth
Publisher: name: No Publisher Supplied
Year: 2010

description: This dissertation explores the autobiographical writings of three women who participated in the Italian Resistance (1943-1945) during World War II, and whose narratives were written between 1943 and 2000. The narratives considered in detail are: Ragazzapartigiana (written in 1946 and published in1974) and Bortolina. Storia di una donna (1996) by Elsa Oliva, Diario partigiano (written between 1943-1945, revisited/revised from 1950 until its publication in 1956) by Ada Gobetti, and Con cuore di donna (2000) by Carla Capponi. I analyze the methods of and motivations behind their varied methods of self-fashioning. In particular, I articulate how these women fashion, create, and negotiate their own identity for themselves and with respect and in response to a greater national audience that has often misrepresented or not represented their wartime experiences. Such a practice then allows them to contribute to the construction of a national identity and national memory in which their individual experiences are accounted for.In executing my analysis, I draw from numerous historical sources (Bravo, Bruzzone, Saba, Alloisio, Beltrami, Pavone, Portelli) to contextualize the narratives, as it is imperative to understand the socio-historic, and cultural environment from which thesenarratives are generated. In addition to socio-historic considerations, I also approach these texts, to varying degrees, through the use of autobiographical (Bernstock, Friedman, Jelinek, Mason), psychological (Gilligan), and sociological (Rowbotham, Chodorow) theoretical material relating to women to illuminate the ways in which these narratives conform with, differ from, or exemplify noted trends of women’s self representation and to help interpret the narrative choices made by the authors. I also avail myself briefly of Italian feminist difference theory (Muraro and Cavarero). My focus throughout, however, is always on the narratives themselves.I ultimately argue that these writings are both inspired by Resistance participation and that for each writer, they are a form of continued resistance to gender based societal assumptions and/or personal historical legacy. That is, while it was their involvement in the Resistance movement that is the basis for the production of these narratives, each author uses her narration of these events to further resist easy or popular categorization of her experiences.
On the Complexity of Enumerating Prime Implicants from Decision-DNNF Circuits
Creators: name: de Colnet, Alexis
name: Marquis, Pierre
Publisher: name: arXiv
Year: 2023
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: We consider the problem EnumIP of enumerating prime implicants of Boolean functions represented by decision decomposable negation normal form (dec-DNNF) circuits. We study EnumIP from dec-DNNF within the framework of enumeration complexity and prove that it is in OutputP, the class of output polynomial enumeration problems, and more precisely in IncP, the class of polynomial incremental time enumeration problems. We then focus on two closely related, but seemingly harder, enumeration problems where further restrictions are put on the prime implicants to be generated. In the first problem, one is only interested in prime implicants representing subset-minimal abductive explanations, a notion much investigated in AI for more than three decades. In the second problem, the target is prime implicants representing sufficient reasons, a recent yet important notion in the emerging field of eXplainable AI, since they aim to explain predictions achieved by machine learning classifiers. We provide evidence showing that enumerating specific prime implicants corresponding to subset-minimal abductive explanations or to sufficient reasons is not in OutputP.
description: 13 pages, including appendices
Spin fluctuations in iron pnictides and chalcogenides: From antiferromagnetism to superconductivity
Creators: name: Inosov, Dmytro S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The present article reviews recent experimental investigations of spin dynamics in iron-based superconductors and their parent compounds by means of inelastic neutron scattering. It mainly focuses on the most contemporary developments in this field, pertaining to the observations of magnetic resonant modes in new superconductors, spin anisotropy of low-energy magnetic fluctuations that has now been observed in a wide range of chemical compositions and doping levels, as well as their momentum-space anisotropy incurred by the spin-nematic order. The implications of these new findings for our understanding of the superconducting state, along with the remaining unsettled challenges for neutron spectroscopy, are discussed.
description: Invited review article for a focus issue of Comptes Rendus Physique: 40 pages, 22 figures, 389 references
EARLINET Single Calculus Chain – technical – Part 1: Pre-processing of raw lidar data
Creators: name: D'Amico, Giuseppe
name: Amodeo, Aldo
name: Mattis, Ina
name: Freudenthaler, Volker
name: Pappalardo, Gelsomina
Publisher: name: München : European Geopyhsical Union
Year: 2016
Subjects: subject: algorithm
subject: backscatter
subject: data quality
subject: hardware
subject: lidar
subject: numerical method
subject: resolution
subject: signal
subject: signal processing
subject: smoothing
subject: software
subject: 550

description: In this paper we describe an automatic tool for the pre-processing of aerosol lidar data called ELPP (EARLINET Lidar Pre-Processor). It is one of two calculus modules of the EARLINET Single Calculus Chain (SCC), the automatic tool for the analysis of EARLINET data. ELPP is an open source module that executes instrumental corrections and data handling of the raw lidar signals, making the lidar data ready to be processed by the optical retrieval algorithms. According to the specific lidar configuration, ELPP automatically performs dead-time correction, atmospheric and electronic background subtraction, gluing of lidar signals, and trigger-delay correction. Moreover, the signal-to-noise ratio of the pre-processed signals can be improved by means of configurable time integration of the raw signals and/or spatial smoothing. ELPP delivers the statistical uncertainties of the final products by means of error propagation or Monte Carlo simulations. During the development of ELPP, particular attention has been payed to make the tool flexible enough to handle all lidar configurations currently used within the EARLINET community. Moreover, it has been designed in a modular way to allow an easy extension to lidar configurations not yet implemented. The primary goal of ELPP is to enable the application of quality-assured procedures in the lidar data analysis starting from the raw lidar data. This provides the added value of full traceability of each delivered lidar product. Several tests have been performed to check the proper functioning of ELPP. The whole SCC has been tested with the same synthetic data sets, which were used for the EARLINET algorithm inter-comparison exercise. ELPP has been successfully employed for the automatic near-real-time pre-processing of the raw lidar data measured during several EARLINET inter-comparison campaigns as well as during intense field campaigns.
title: Merits of timing a woman’s menstrual cycle in performing an MRI to stage endometriosis
Creators: name: McElroy, Sarah
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2023
Subjects: subject: Pelvis
subject: MR
subject: Screening
subject: Outcomes

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: We undertook a review of the literature to assess if timing an endometriosis staging MRI examination to the patient’s menstrual cycle improves diagnosis. Secondary aims of the review were to collate information on MRI findings typically seen when...
Additional file 2 of Targeting interleukin-6 as a treatment approach for peritoneal carcinomatosis
Creators: name: Dadgar, Neda
name: Sherry, Christopher
name: Zimmerman, Jenna
name: Park, Hyun
name: Lewis, Catherine
name: Donnenberg, Albert
name: Zaidi, Ali H.
name: Fan, Yong
name: Xiao, Kunhong
name: Bartlett, David
name: Donnenberg, Vera
name: Wagner, Patrick L.
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 2
Flat band ferromagnetism without connectivity conditions in the flat band
Creators: name: Gulacsi, Miklos
name: Kovacs, Gyorgy
name: Gulacsi, Zsolt
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: It is known that a system which exhibits a half filled lowest flat band and the localized one-particle Wannier states on the flat band satisfy the connectivity conditions, is always ferromagnetic. Without the connectivity conditions on the flat band, the system is non-magnetic. We show that this is not always true. The reason is connected to a peculiar behavior of the band situated just above the flat band.
description: 15 pages, 4 figures
Additional file 1: of Evidence supporting regulatory-decision making on orphan medicinal products authorisation in Europe: methodological uncertainties
Creators: name: Pontes, Caridad
name: Fontanet, Juan
name: Vives, Roser
name: Aranzazu Sancho
name: Mònica Gómez-Valent
name: Ríos, José
name: Morros, Rosa
name: Martinalbo, Jorge
name: Posch, Martin
name: Koch, Armin
name: Roes, Kit
name: Rengerink, Katrien Oude
name: Torrent-Farnell, Josep
name: Torres, Ferran
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Table S1. Characteristics used to describe the evidence supporting marketing authorization application in European Public Assessment Reports of Orphan Medicinal Products. Table S2. Clustering of the 85 medical conditions in European Public Assessment Reports of Orphan Medicinal Products. Table S3. Dictionary of some methodological terms. Figure S1. Number of European Public Assessment Reports in each cluster. (DOCX 47 kb)
title: The role of post-op RT in Pelvic Ewing’s Sarcoma- a systematic review
Creators: name: Lim Yew Fai, Tracy
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2023
Subjects: subject: Paediatric
subject: Pelvis
subject: Soft tissues / Skin
subject: Other
subject: Radiation therapy / Oncology
subject: Multidisciplinary cancer care
subject: Outcomes
subject: Toxicity

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Ewing’s Sarcoma (ES) is a rare malignancy of bone and soft tissue, and approximately 20-26% of ES are located in the pelvis. Despite advances in treatment over time, pelvic ES continues to be associated with poorer outcomes compared to other...
Molecular clouds at the eastern edge of radio nebula W50
Creators: name: Sakemi, Haruka
name: Machida, Mami
name: Yamamoto, Hiroaki
name: Tachihara, Kengo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Microquasar SS 433 located at the geometric center of radio nebula W50 is a suitable source for investigating the physical process of how galactic jets affect the surrounding interstellar medium (ISM). Previous studies have searched for evidence of the interaction between the SS 433 jet and ISM, such as neutral hydrogen gas and molecular clouds; however, it is still unclear which ISM interacts with the jet. We looked for new molecular clouds that possibly interact at the terminal of the SS 433 eastern jet using the Nobeyama 45-m telescope and the Atacama Submillimeter Telescope Experiment (ASTE). We identified two molecular clouds, comprising many small clumps, in the velocity range of 30.1--36.5 km s$^{-1}$ for the first time. These clouds have complex velocity structures, and one of them has a density gradient toward SS 433. Although it is difficult to conclude the relation between the molecular clouds and the SS 433/W50 system, there is a possibility that the eastern structure of W50 constructed by the SS 433 jet swept up tiny molecular clumps drifting in the surroundings and formed the molecular clouds that we identified in this study.
description: 22 pages, 11 figures, accepted for publication in PASJ