cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
In vivo measured joint friction in hip implants during walking after a short rest
Creators: name: Damm, Philipp
name: Bender, Alwina
name: Duda, Georg
name: Bergmann, Georg
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Introduction It has been suspected that friction in hip implants is higher when walking is initiated after a resting period than during continuous movement. It cannot be excluded that such increased initial moments endanger the cup fixation in the acetabulum, overstress the taper connections in the implant or increase wear. To assess these risks, the contact forces, friction moments and friction coefficients in the joint were measured in vivo in ten subjects. Instrumented hip joint implants with telemetric data transmission were used to access the contact loads between the cup and head during the first steps of walking after a short rest. Results The analysis demonstrated that the contact force is not increased during the first step. The friction moment in the joint, however, is much higher during the first step than during continuous walking. The moment increases throughout the gait cycle were 32% to 143% on average and up to 621% individually. The high initial moments will probably not increase wear by much in the joint. However, comparisons with literature data on the fixation resistance of the cup against moments made clear that the stability can be endangered. This risk is highest during the first postoperative months for cementless cups with insufficient under- reaming. The high moments after a break can also put taper connections between the head and neck and neck and shaft at a higher risk. Discussion During continuous walking, the friction moments individually were extremely varied by factors of 4 to 10. Much of this difference is presumably caused by the varying lubrication properties of the synovia. These large moment variations can possibly lead to friction-induced temperature increases during walking, which are higher than the 43.1°C which have previously been observed in a group of only five subjects.
Host involvement in the replication of potato spindle tuber viroid and the evolutionary relationship between plant viroids and the hepatitis delta virus
Creators: name: Bojic, Teodora
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Chemistry, Biochemistry.
subject: Biology, Virology.

description: The present study examines the interaction between host RNA polymerase II (RNAP II) and potato spindle tuber viroid (PSTVd), with the goal of locating and characterizing a putative RNAP II promoter within the viroid's RNA genome. By using a co-immunoprecipitation approach coupled with deletion and mutational analysis, RNAP II was shown to specifically bind the left terminal hairpin loop of PSTVd(+) RNA. The interaction with RNAP II appears to be dependent on PSTVd secondary structure features, rather than a particular sequence. These findings provide direct evidence of association between RNAP II and PSTVd RNA, and render a unique example of a possible RNA promoter for RNAP II. The second part of the study examines the evolutionary relationship between viroids and the hepatitis delta virus (HDV), as these pathogens share key structural and functional characteristics. We conclude, based on infection experiments, that HDV and viroids share common strategies and host factors to fulfill their respective life-cycles. We found that both HDV and an HDV mutant lacking the HDAg protein-coding region (miniHDV) can replicate in a plant host. However, miniHDV and PSTVd can replicate in human cells only in the presence of the small delta antigen (HDAg-S). Together, these results provide support for the hypothesis that HDV evolved from a viroid-like element through the capture of a cellular transcript necessary for its adaptation to a human host.
title: Traumatismo craneoencefálico en niños: ¿SUTURA O FRACTURA?
Creators: name: Fernández Jara, Javier
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Paediatric
subject: Anatomy
subject: Musculoskeletal bone

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Claves para diferenciar sutura y fractura ante un traumatismo craneoencefálico en un niño Ilustrar la anatomía normal de las suturas normales y accesorias Ayudar en el diagnóstico con algunos casos...
Puberty, peers and risky behaviour: An examination of the relationships between pubertal development, peer affiliation, sexual behaviour and delinquency
Creators: name: Clark, Laurie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Psychology, Clinical.

description: The present study is an investigation of the relationships between pubertal timing, peer and romantic relationships, and delinquent and risk-taking behaviour in a sample that included youth heavily involved in such behaviours. Ninety-nine youth, males and females aged 13 to 19, were recruited through public advertisements (Community Group) and community agencies who serve youth involved with the justice system (Justice Group) to participate in the study. Youth were interviewed individually to assess peer relationships, romantic relationships, delinquent behaviour and drug use, and completed questionnaires to assess pubertal development, sexual behaviour, relations with opposite-sex peers and social desirability response bias. In order to determine the relationship between pubertal timing and involvement with delinquent peers on the one hand, and the behaviours of interest on the other, standard regression analyses were conducted. It was found that pubertal timing did not account significantly for any of the variance in delinquency, drug use, or sexual behaviour scores with one minor exception. For males, both involvement with delinquent peers and pubertal timing were significant predictors of sexual behaviour variety scores, such that late pubertal timing and greater association with delinquent peers were associated with higher sexual variety scores. Gender comparisons, investigated via a series of ANCOVAs, found that males reported engaging in a greater variety of delinquent behaviours and a greater frequency of delinquent behaviours across their lifetime than did females. Males also reported an earlier age of onset of delinquent behaviour, by approximately 2 years. However, there was no gender difference in past year frequency of delinquent behaviour, nor on any of the indices of drug use and sexual behaviour. Justice Group Females reported significantly greater mean age differences (2.45 years) between their romantic partners and themselves in comparison to the three other participant groups.
Supplementary document for Probing variations of fibrous structures during the development of breast ductal carcinoma tissues via quantitative Mueller matrix imaging - 4746072.pdf
Creators: name: Dong, Yang
name: Shaoxiong, Liu
name: Shen, Yuanxing
name: He, Honghui
name: Ma, Hui
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: expanded description of method
title: Complementary medicine in nursing homes
title: results of a mixed methods pilot study
titleType: Subtitle
Creators: name: Ortiz, Miriam
name: Ammann, Eva Soom
name: Gross, Corina Salis
name: Schnabel, Katharina
name: Walbaum, Torsten
name: Binting, Sylvia
name: Fischer, Herbert Felix
name: Teut, Michael
name: Kottner, Jan
name: Suhr, Ralf
name: Brinkhaus, Benno
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background ‘Kneipp Therapy’ (KT) is a form of Complementary and Alternative Medicine (CAM) that includes a combination of hydrotherapy, herbal medicine, mind-body medicine, physical activities, and healthy eating. Since 2007, some nursing homes for older adults in Germany began to integrate CAM in the form of KT in care. The study investigated how KT is used in daily routine care and explored the health status of residents and caregivers involved in KT. Methods We performed a cross-sectional pilot study with a mixed methods approach that collected both quantitative and qualitative data in four German nursing homes in 2011. Assessments in the quantitative component included the Quality of Life in Dementia (QUALIDEM), the Short Form 12 Health Survey (SF-12), the Barthel-Index for residents and the Work Ability Index (WAI) and SF-12 for caregivers. The qualitative component addressed the residents’ and caregivers’ subjectively experienced changes after integration of KT. It was conceptualized as an ethnographic rapid appraisal by conducting participant observation and semi-structured interviews in two of the four nursing homes. Results The quantitative component included 64 residents (53 female, 83.2 ± 8.1 years (mean and SD)) and 29 caregivers (all female, 42.0 ± 11.7 years). Residents were multimorbid (8 ± 3 diagnoses), and activities of daily living were restricted (Barthel-Index 60.6 ± 24.4). The caregivers’ results indicated good work ability (WAI 37.4 ± 5.1), health related quality of life was superior to the German sample (SF-12 physical CSS 49.2 ± 8.0; mental CSS 54.1 ± 6.6). Among both caregivers and residents, 89% considered KT to be positive for well-being. The qualitative analysis showed that caregivers perceived emotional and functional benefits from more content and calmer residents, a larger variety in basic care practices, and a more self-determined scope of action. Residents reported gains in attention and caring, and recognition of their lay knowledge. Conclusion Residents showed typical characteristics of nursing home inhabitants. Caregivers demonstrated good work ability. Both reported to have benefits from KT. The results provide a good basis for future projects, e.g. controlled studies to evaluate the effects of CAM in nursing homes.
Verhaltensregeln für Ihren Besuch in der Antarktis
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2013
Subjects: subject: Antarktisvertrag
subject: Fremdenverkehr
subject: Öffentlichkeitsarbeit
subject: Antarktis
subject: Antarktikvertrag
subject: Tourismus
subject: Verhaltensmuster
subject: Nachhaltigkeit | Strategien | Internationales
subject: Sustainability | Strategies | International matters

description: Seit Beginn des Antarktistourismus, der sich vor allem auf die Antarktische Halbinsel konzentriert, haben die Besucherzahlen erheblich zugenommen. Um die einmalige Tier- und Pflanzenwelt trotz des wachsenden Besucherinteresses in seiner Ursprünglichkeit auch in Zukunft zu erhalten, gelten international verbindliche Verhaltensregeln für die Besucher der Antarktis. Beachten Sie diese Verhaltensregeln bei Ihrem Aufenthalt vor Ort, leisten Sie persönlich einen Beitrag zum Schutz der Antarktis leisten.
Teaching economics and environmentalism within a conservative curriculum
Creators: name: Harkness, Peter G. L.
Publisher: name: Swinburne
Year: 2024

description: Over the years the author has noticed his students seem to be becoming more conservative, politically. Even global warming and the impending environmental crisis bother few of them. They are inclined to regard our economic system and the status quo as entirely legitimate. That society could, or should be radically altered and improved has not occurred to most of them. If we don't teach our students to question society, and to see that it could be better, there is little hope that the next generation will endeavour to improve the world. This paper analyses the (conservative) way Economics typically explains two major social problems: poverty, and environmental degradation. Conservatives represent poverty and environmental degradation as unexpected aberrations in our otherwise benevolent capitalist economic system. Their solutions are usually minimalist and don't tamper with the system. More radical teachers view environmental destruction and poverty as inevitable outcomes of capitalism. These are symptoms of a more fundamental problem: modern capitalism. This is what needs to be fixed. This paper describes the essence of these two different perspectives. Furthermore, it summarises experiences in teaching critical thinking about questions of poverty and environmental degradation within an Economics curriculum which emphasizes a more conservative approach.
Correction: Fu et al. Long-Term Atmospheric Visibility Trends and Characteristics of 31 Provincial Capital Cities in China during 1957–2016. Atmosphere, 2018, 9, 318
Creators: name: Fu, Weicong
name: Chen, Ziru
name: Zhu, Zhipeng
name: Liu, Qunyue
name: Qi, Jinda
name: Dang, Emily
name: Wang, Minhua
name: Dong, Jianwen
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The authors would like to correct the published article[...]
Transparent electrodes based on silver nanowire networks: From physical considerations towards device integration
Creators: name: Bellet, Daniel
name: Lagrange, Melanie
name: Sannicolo, Thomas
name: Aghazadehchors, Sara
name: Nguyen, Viet Huong
name: Langley, Daniel
name: Munoz-Rojas, David
name: Jimenez, Carmen
name: Brechet, Yves
name: Nguyen, Ngoc Duy
Publisher: name: Swinburne
Year: 2024

description: The past few years have seen a considerable amount of research devoted to nanostructured transparent conducting materials (TCM), which play a pivotal role in many modern devices such as solar cells, flexible light-emitting devices, touch screens, electromagnetic devices, and flexible transparent thin film heaters. Currently, the most commonly used TCM for such applications (ITO: Indium Tin oxide) suffers from two major drawbacks: brittleness and indium scarcity. Among emerging transparent electrodes, silver nanowire (AgNW) networks appear to be a promising substitute to ITO since such electrically percolating networks exhibit excellent properties with sheet resistance lower than 10 W/sq and optical transparency of 90%, fulfilling the requirements of most applications. In addition, AgNW networks also exhibit very good mechanical flexibility. The fabrication of these electrodes involves low-temperature processing steps and scalable methods, thus making them appropriate for future use as low-cost transparent electrodes in flexible electronic devices. This contribution aims to briefly present the main properties of AgNW based transparent electrodes as well as some considerations relating to their efficient integration in devices. The influence of network density, nanowire sizes, and post treatments on the properties of AgNW networks will also be evaluated. In addition to a general overview of AgNW networks, we focus on two important aspects: (i) network instabilities as well as an efficient Atomic Layer Deposition (ALD) coating which clearly enhances AgNW network stability and (ii) modelling to better understand the physical properties of these networks.
title: Taxane-cisplatin-fluorouracil as induction chemotherapy for advanced head and neck cancer
title: a meta-analysis of the 5-year efficacy and safety
titleType: Subtitle
Creators: name: Qian, Xu
name: Ma, Chenming
name: Hoffmann, Thomas K.
name: Kaufmann, Andreas M.
name: Albers, Andreas E.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: Head and neck carcinoma
subject: Induction chemotherapy
subject: Docetaxel
subject: Cisplatin
subject: Fluoruracil
subject: Survival
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background The objective of this study was to compare the efficacy and safety of taxane (docetaxel or paclitaxel), cisplatin, and fluorouracil (Tax-PF) with cisplatin plus fluorouracil (PF) regimen by a meta-analysis of data retrieved from the literature. Methods Seven randomized clinical trials were identified, which included patients with advanced head and neck cancer who underwent induction chemotherapy with either a Tax-PF or PF protocol. The outcomes included the 3-year and 5-year overall survival (OS) and progression-free survival (PFS), overall response rate (ORR) and different types of adverse events. Results The 3-year OS rate (HR: 1.14; 95% CI: 1.03 to 1.25; P = 0.008), 3-year PFS rate (HR: 1.24; 95% CI: 1.08 to 1.43; P = 0.002), 5-year OS rate (HR: 1.30; 95% CI, 1.09 to 1.55;P = 0.003), 5-year PFS rate (HR: 1.39; 95% CI, 1.14 to 1.70; P = 0.001) and ORR to chemotherapy (OR 1.66; 95% CI, 1.35 to 2.05; P
Signatures of magnetism control by flow of angular momentum
Creators: name: Chen, L.
name: Sun, Y.
name: Mankovsky, S.
name: Meier, T. N. G.
name: Kronseder, M.
name: Sun, C.
name: Orekhov, A.
name: Ebert, H.
name: Weiss, D.
name: Back, C. H.
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: 530 Physik

description: Exploring new strategies to manipulate the order parameter of magnetic materials by electrical means is of great importance not only for advancing our understanding of fundamental magnetism but also for unlocking potential applications. A well-established concept uses gate voltages to control magnetic properties by modulating the carrier population in a capacitor structure1,2,3,4,5. Here we show that, in Pt/Al/Fe/GaAs(001) multilayers, the application of an in-plane charge current in Pt leads to a shift in the ferromagnetic resonance field depending on the microwave frequency when the Fe film is sufficiently thin. The experimental observation is interpreted as a current-induced modification of the magnetocrystalline anisotropy ΔHA of Fe. We show that (1) ΔHA decreases with increasing Fe film thickness and is connected to the damping-like torque; and (2) ΔHA depends not only on the polarity of charge current but also on the magnetization direction, that is, ΔHA has an opposite sign when the magnetization direction is reversed. The symmetry of the modification is consistent with a current-induced spin6,7,8 and/or orbit9,10,11,12,13 accumulation, which, respectively, act on the spin and/or orbit component of the magnetization. In this study, as Pt is regarded as a typical spin current source6,14, the spin current can play a dominant part. The control of magnetism by a spin current results from the modified exchange splitting of the majority and minority spin bands, providing functionality that was previously unknown and could be useful in advanced spintronic devices.
Studying the central spindle-associated Rho guanine nucleotide exchange factor ECT2 during meiotic cytokinesis
Creators: name: Arabi Katbi, Hadia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Chemistry, Biochemistry.

description: Polar body formation has been of great interest both as a fundamental process in sexual reproduction and as an extreme example of asymmetric cell division (cytokinesis) in cell biology. The guanine nucleotide exchange factor ECT2 regulates cytokinesis in all metazoans analyzed to date. Although it has been known that ECT2 is required for the localization of active RhoA to the equatorial cortex, its role in vertebrate polar body emission is not explored yet. It is believed that ECT2 is the GEF for RhoA during mitotic cytokinesis. However, there is no direct evidence supporting co-localization of ECT2 with Rho contractile ring, at least during the early stage of cytokinesis. To investigate this hypothesis, we employed fluorescence confocal microscopy to reveal for the first time that ECT2 never overlaps with the active RhoA zone in the oocytes during polar body emission. These results suggest that, although ECT2 function is required for Rho contractile ring formation and constriction, ECT2 is unlikely the direct activator of RhoA during polar body emission. More importantly, our time-lapse imaging experiments with ECT2 and active Rho reveals an exciting mechanism by which Cdc42, a small Rho GTPase, regulates polar body emission: during Rho contractile ring constriction, Cdc42 promotes membrane protrusion to "pull" one spindle pale and the associated polar body chromosomes into the forming polar body enclosure.
Power system blackouts: lessons learned
Creators: name: Hosseinzadeh, Nasser
Publisher: name: Swinburne
Year: 2024

description: In August 2003, large areas of the Midwest and Northeast United States and Ontario, Canada, experienced an electric power blackout. The outage affected 50 million people and about 62000 megawatts (MW) of electric load. The final report on the August 14, 2003 blackout by the US-Canada Power System Outage Task Force makes clear that this blackout could have been prevented! Similar events, but in a lesser extent, happened in Europe at about the same time. Some other major outages had occurred around the globe prior to the great blackout of 2003. What are the lessons learned from these blackouts? This paper will partially address this question. It will also explore the relevance of these lessons to the electric power network in Australia.
Comparability of activity monitors used in Asian and Western-country studies for assessing free-living sedentary behaviour
Creators: name: Kurita, Satoshi
name: Yano, Shohei
name: Ishii, Kaori
name: Shibata, Ai
name: Sasai, Hiroyuki
name: Nakata, Yoshio
name: Fukushima, Noritoshi
name: Inoue, Shigeru
name: Tanaka, Shigeho
name: Sugiyama, Takemi
name: Owen, Neville
name: Oka, Koichiro
Publisher: name: Swinburne
Year: 2024

description: This study aims to compare the outputs of the waist-worn Active style Pro HJA-350IT (ASP; used in studies with Asian populations), the waist-worn ActiGragh™GT3X+ using the normal filter (GT3X+) and the thigh-worn activPAL3 (AP) in assessing adults’ sedentary behaviour (total sedentary time, number of breaks) under free-living conditions. Fifty healthy workers wore the three monitors simultaneously during their waking hours on two days, including a work day and a non-work day. Valid data were at least 10 hours of wearing time, and the differences between monitors on the sedentary outputs using the AP as criterion measurement were analyzed by ANOVA. The number of participants who had complete valid data for work day and non-work day was 47 and 44, respectively. Total sedentary time and breaks estimated by the AP were respectively 466.5 ± 146.8 min and 64.3 ± 24.9 times on the work day and 497.7 ± 138.3 min and 44.6 ± 15.4 times on the non-work day. In total sedentary time, the ASP estimated 29.7 min (95%CI = 7.9 to 51.5) significantly shorter than the AP on the work day but showed no significant difference against the AP on the non-work day. The GT3X+ estimated 80.1 min (54.6 to 105.6) and 52.3 (26.4 to 78.2) significantly longer than the AP on the work day and the non-work day, respectively. For the number of breaks from sedentary time, on both days, the ASP and the GT3X+ estimated significantly more than the AP: 14.1 to 15.8 times (6.3 to 22.5) for the ASP and 27.7 to 28.8 times (21.8 to 34.8) for the GT3X+. Compared to the AP as the criterion, the ASP can underestimate total sedentary time and the GT3X+ can overestimate it, and more so at the lower levels of sedentary time. For breaks from sedentary time, compared to the AP, both the GT3X+ the ASP can overestimate.
title: Aneurisma de la arteria pancreaticoduodenal y estenosis del tronco celiaco, otra causa de sangrado gastrointestinal agudo.
Creators: name: Caldera Díaz, Adriana Carolina
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir la fisiopatología,
hallazgos radiológicos y tratamiento de los aneurismas de la arteria pancreaticoduodenal asociados a estenosis del tronco celíaco,
como causa de sangrado gastrointestinal...
Hyperspectral Unmixing with Bandwise Generalized Bilinear Model
Creators: name: Li, Chang
name: Liu, Yu
name: Cheng, Juan
name: Song, Rencheng
name: Peng, Hu
name: Chen, Qiang
name: Chen, Xun
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Generalized bilinear model (GBM) has received extensive attention in the field of hyperspectral nonlinear unmixing. Traditional GBM unmixing methods are usually assumed to be degraded only by additive white Gaussian noise (AWGN), and the intensity of AWGN in each band of hyperspectral image (HSI) is assumed to be the same. However, the real HSIs are usually degraded by mixture of various kinds of noise, which include Gaussian noise, impulse noise, dead pixels or lines, stripes, and so on. Besides, the intensity of AWGN is usually different for each band of HSI. To address the above mentioned issues, we propose a novel nonlinear unmixing method based on the bandwise generalized bilinear model (NU-BGBM), which can be adapted to the presence of complex mixed noise in real HSI. Besides, the alternative direction method of multipliers (ADMM) is adopted to solve the proposed NU-BGBM. Finally, extensive experiments are conducted to demonstrate the effectiveness of the proposed NU-BGBM compared with some other state-of-the-art unmixing methods.
title: Neuroimagen en el paciente VIH
Creators: name: Viguer Benavent, Rosa María
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: CT
subject: MR
subject: AIDS

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Los objetivos de este trabajo son: 1.
Revisión de la semiología radiológica de las afecciones del SNC en pacientes VIH más frecuentemente halladas en nuestro centro. 2.Repasar el manejo radiológico del paciente VIH con afectación neurológica....
Updating the waste prevention programme
Creators: name: Wilts, Henning
name: Azak, Gunda
name: Feder, Lina
Publisher: name: Umweltbundesamt
Year: 2020
Subjects: subject: Bewertung
subject: waste prevention programm
subject: Evaluation
subject: status of implementation
subject: Waste | Resources

description: Article 29 of Directive 2008/98/EC requires that Member States adopt waste prevention programmes (WPP). The German Federal Government first adopted the programme in July 2013 under the title "Abfallvermeidungsprogramm des Bundes unter Beteiligung der Länder"("Waste Prevention Programme of the German Government with the Involvement of the Federal States"). The German WPP is to be evaluated every 6 years and updated as required in Section 33 of the German Circular Economy Act. Under the circumstances of the upcoming review of the WPP due by 2019, the current status of the implementation of the WPP was to be determined and evaluated during this project. Other aspects not previously addressed in the WPP were also to be examined to see whether they contribute to waste prevention. Specific proposals to possibly develop and update the programme were elaborated based on the results of the analysis of the current status of the implementation of the WPP at the federal, state and municipal levels and an evaluation of existing prevention potentials. Specific proposals for measures concerning previously prioritised waste streams and relevant priority prevention approaches were developed to facilitate this. Quelle: Forschungsbericht
description: The waste prevention program (WPP) from 2013 must be evaluated every 6 years and updated if necessary. The review and evaluation of the implementation of the WPP took place within the scope of the project. Based on the analysis results for the implementation of the WPP at federal, state and municipal level and an assessment of existing prevention potentials, concrete proposals for a possible further development and updating of the program on prioritized waste streams and corresponding priority prevention approaches were developed. In addition, structural adjustment and change needs of the WPP were worked out and further research was shown.
An investigation of BMP-7 mediated alterations to BMP signalling components in human tenocyte-like cells
Creators: name: Klatte-Schulz, Franka
name: Giese, Gerry
name: Differ, Christopher
name: Minkwitz, Susann
name: Ruschke, Karen
name: Puts, Regina
name: Knaus, Petra
name: Wildemann, Britt
Publisher: name: Freie Universität Berlin
Year: 2016
Subjects: subject: Cell signalling
subject: Medical research
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The incidence of tendon re-tears post-surgery is an ever present complication. It is suggested that the application of biological factors, such as bone morphogenetic protein 7 (BMP-7), can reduce complication rates by promoting tenogenic characteristics in in vitro studies. However, there remains a dearth of information in regards to the mechanisms of BMP-7 signalling in tenocytes. Using primary human tenocyte-like cells (hTLCs) from the supraspinatus tendon the BMP-7 signalling pathway was investigated: induction of the BMP associated Smad pathway and non-Smad pathways (AKT, p38, ERK1/2 and JNK); alterations in gene expression of BMP-7 associated receptors, Smad pathway components, Smad target gene (ID1) and tenogenic marker scleraxis. BMP-7 increases the expression of specific BMP associated receptors, BMPR-Ib and BMPR-II, and Smad8. Additionally, BMP-7 activates significantly Smad1/5/8 and slightly p38 pathways as indicated by an increase in phosphorylation and proven by inhibition experiments, where p-ERK1/2 and p-JNK pathways remain mainly unresponsive. Furthermore, BMP-7 increases the expression of the Smad target gene ID1, and the tendon specific transcription factor scleraxis. The study shows that tenocyte-like cells undergo primarily Smad8 and p38 signalling after BMP-7 stimulation. The up-regulation of tendon related marker genes and matrix proteins such as Smad8/9, scleraxis and collagen I might lead to positive effects of BMP-7 treatment for rotator cuff repair, without significant induction of osteogenic and chondrogenic markers.
Supplementary document for Proposal for photoacoustic ultrasonic generator based on Tamm plasmon structures - 4746381.pdf
Creators: name: Girshova, Elizaveta
name: Mikitchuk, Alena
name: Belonovski, Alexey
name: Morozov, Konstantin
name: Pozina, Galia
name: Ivanov, Konstantin
name: Kozadaev, Konstantin
name: Egorov, Anton
name: Kaliteevskii, M A
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental document
Double-hit lymphoma of the male breast: a case report
Creators: name: Elgaafary, Shaymaa
name: Nagel, Inga
name: López, Cristina
name: Bens, Susanne
name: Szczepanowski, Monika
name: Wagener, Rabea
name: Klapper, Wolfram
name: Siebert, Reiner
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: MYC
subject: BCL2
subject: Burkitt
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Lymphoma
subject: Breast
subject: Male
subject: Burkitt-Lymphom

description: Background Whereas lymphoma of the female breast is already rare, lymphoma of the male breast has only anecdotally been reported. Within a study of 32 lymphoma of the breast reported between 1973 and 2014 as Burkitt lymphoma, we observed a single male case, which we report here. Case presentation A 72-years-old Caucasian man presented with a mass in his left breast. Clinical history included prior basal cell carcinoma, leiomyosarcoma, and administration of spironolactone. The reference pathology diagnosis at presentation was Burkitt lymphoma according to the Kiel Classification. The present re-investigation using fluorescence in situ hybridization revealed an IGH-MYC translocation and a break in the BCL2 locus in the tumor cells. Thus, in light of the current WHO classification, the diagnosis was revised to high-grade B-cell lymphoma with MYC and BCL2 rearrangement, Burkitt morphology (so-called “double-hit” lymphoma). Genome-wide chromosomal imbalance mapping revealed a complex pattern of aberrations in line with this diagnosis. The aberrations, including copy-number gains in chromosomes 3q and 18 and focal homozygous loss in 9p21.3, resembled typical changes of lymphomas affecting “immune-privileged” sites. Conclusion The present case adds to the understanding of the pathogenesis of male breast lymphomas, about which hardly any molecular characterization has been published yet.
title: Sindrome de Vena Cava Superior: ¿El intervencionismo vascular es una opción terapéutica?
Creators: name: López Martínez, José Luis
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Obstruction / Occlusion
subject: Neoplasia
subject: Embolism / Thrombosis
subject: Recanalisation
subject: Stents
subject: Catheter venography
subject: Fluoroscopy
subject: Interventional vascular

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Exponer la alternativa del intervencionismo endovascular del síndrome de vena cava superior (SVCS) a la actitud clásica de la cirugía. Mostrar nuestra experiencia en la realización de las diferentes técnicas y material utilizado en el...
The positive keys to gazelles' success: empirical evidence
Creators: name: Zbierowski, P.
name: Bratnicki, M.
name: Kozlowski, R.
name: Gabrys, B.
Publisher: name: Swinburne
Year: 2024

description: The paper attempts to investigate what kind of positive traits and characteristics are possessed by highperforming SMEs and how are they used to achieve high performance. The study is built on two main areas of knowledge: positive organisational scholarship (POS) and high performance organisation (HPO). The model of positive characteristics of high performing SMEs based on theory of organisational fit is used. For each of components of organisational design positive characteristics leading to high performance are attributed. Those characteristics are put into research along with multidimensional objective and subjective measures of organisational performance. Research methods used is data envelopment analysis (DEA). Each of investigated companies has a different profile of both performance and positive characteristics. Performance profiles vary from focus on short-term performance to focus on growth, however all subjective measures are high and all firms managed to balance long- and short-term performance. Among input characteristics clear vision, committed leadership and flexible structure are common for entire group, other traits are also used in various patterns.
title: Semiología de las artropatías y sus complicaciones
Creators: name: Caba Cuevas, Monica
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Pathology
subject: Diagnostic procedure
subject: CT
subject: MR
subject: Musculoskeletal soft tissue
subject: Musculoskeletal bone

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Identificar los hallazgos radiológicos claves de las artropatías más frecuentes en la práctica clínica. Evaluar la utilidad de otras técnicas radiológicas como la Resonancia Magnética(RM) en la valoración de las...
Formation of substituted phenalenes from the Birch reduction of pyrene and perylene.
Creators: name: Das, N. C.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1967
Subjects: subject: Chemistry, Inorganic.

description: The Birch reduction of pyrene and perylene was investigated under a variety of conditions. 1. The reduction of pyrene (1) with four equivalents of sodium in liquid ammonia in the presence of ethanol (ether was used as a co-solvent) gave 89% of a mixture of 1,2,3,6-tetrahydropyrene (2) and 1,2,3,5-tetrahydropyrene (3) (in a ratio 2:1), 8% 1,2,3,3a,4,5,5a,6,7,8-decahydropyrene (5) and 3% recovered pyrene. 2. The reduction of pyrene with two equivalents of sodium under the same experimental conditions as [1] gave 45% tetrahydropyrenes (2 and 3), 2% decahydropyrene (5) and the balance was recovered pyrene. 3. The protonation of pyrene anion (prepared from pyrene with two equivalents of sodium in liquid ammonia - ether used as co-solvent) with ethanol or t-BuOH gave 30% tetrahydropyrenes (2 and 3), 10% 4,5-dihydropyrene (12) and the balance was recovered pyrene. 4. The protonation of pyrene anion (prepared as in [3]) with water gave 55% 1, 2-dihydropyrene (16), 5% 4,5-dihydropyrene (12) and the balance was recovered pyrene. 5. Methylation of the above pyrene anion gave 4-methylpyrene (76) and 2-methylpyrene (78) in the ratio 3:1 respectively. 6. Reduction of pyrene (1) with lithium in ethylenediamine (modified Birch reduction) gave tetrahydropyrenes (2 and 3) as absolute products. (Abstract shortened by UMI.)
The time of flight method applied to 2.37 MeV neutrons.
Creators: name: Hsu, Tung-Hong.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1964
Subjects: subject: Physics, Nuclear.

description: A time of flight system using an associated particle detector was developed for use with DD neutrons of 2.37 MeV. As part of this system a new method of neutron gamma discrimination based on the Owen principle was developed; this method distinguishes 0.5 MeV neutrons from a very wide energy range of gamma rays. This apparatus was then used to measure the angular distributions of the neutrons scattered from the ground state and the 0.845 MeV state of Fe56.
title: Embolización Arterial de la Hemorragia Digestiva Alta No Variceal (HDANV)
Creators: name: Rodriguez Rosales, Gracia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Interventional vascular
subject: Gastrointestinal tract
subject: Emergency
subject: Catheter arteriography
subject: Embolisation
subject: Haemorrhage

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Fig. 1 Revisar el papel de la embolización arterial en la HDANV,
describiendo las indicaciones,
la técnica y los resultados en las diferentes series...
A network analysis of the fear of COVID-19 scale (FCV-19S): a large-scale cross-cultural study in Iran, Bangladesh, and Norway
Creators: name: Lecuona, Oscar
name: Lin, Chung-Ying
name: Rozgonjuk, Dmitri
name: Norekvål, Tone M.
name: Iversen, Marjolein M.
name: Mamun, Mohammed A.
name: Griffiths, Mark D.
name: Lin, Ting-I
name: Pakpour, Amir H.
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: network analysis
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Bangladesh
subject: Iran
subject: System analysis
subject: Norway
subject: COVID-19
subject: Fear
subject: Bangladesch
subject: Furcht
subject: Netzwerkanalyse
subject: Norwegen

description: The rapid spread of the coronavirus disease 2019 (COVID-19) has led to high levels of fear worldwide. Given that fear is an important factor in causing psychological distress and facilitating preventive behaviors, assessing the fear of COVID-19 is important. The seven-item Fear of COVID-19 Scale (FCV-19S) is a widely used psychometric instrument to assess this fear. However, the factor structure of the FCV-19S remains unclear according to the current evidence. Therefore, the present study used a network analysis to provide further empirical evidence for the factor structure of FCV-19S. A total of 24,429 participants from Iran (n = 10,843), Bangladesh (n = 9906), and Norway (n = 3680) completed the FCV-19S in their local language. A network analysis (via regularized partial correlation networks) was applied to investigate the seven FCV-19S items. Moreover, relationships between the FCV-19S items were compared across gender (males vs. females), age groups (18–30 years, 31–50 years, and >50 years), and countries (Iran, Bangladesh, and Norway). A two-factor structure pattern was observed (three items concerning physical factors, including clammy hands, insomnia, and heart palpitations; four items concerning psychosocial factors, including being afraid, uncomfortable, afraid of dying, and anxious about COVID-19 news). Moreover, this pattern was found to be the same among men and women, across age groups and countries. The network analysis used in the present study verified the two-factor structure for the FCV-19S. Future studies may consider using the two-factor structure of FCV-19S to assess the fear of COVID-19 during the COVID-19 era.
Ausschreibung von Regionalstrom durch öffentliche Auftraggeber
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2022
Subjects: subject: Beschaffung
subject: Umweltverträglichkeit
subject: Regionalstrom
subject: Regionalnachweise
subject: Strom
subject: umweltfreundlich
subject: regional
subject: Klima | Energie

description: Das Gutachten setzt sich mit der Frage auseinander, ob öffentliche Auftraggeber im Rahmen eines Vergabeverfahrens i.S.v. § 97 ff. GWB als Beschaffungsgegenstand Regionalstrom (nach § 79a EEG oder anderweitig nachgewiesen) festlegen dürfen. Das aus dem vergaberechtlichen Wettbewerbsgrundsatz folgende "Gebot der produktneutralen Ausschreibung" scheint dem zunächst entgegenzustehen. Allerdings rechtfertigt das Prinzip der "Regionalen Klimaneutralität" sachlich eine Ausnahme von diesem Gebot. Im Ergebnis wird die Ausschreibung von Regionalstrom durch den öffentlichen Auftraggeber daher als vergaberechtlich zulässig angesehen, solange und soweit dies nachweislich zur Umsetzung eines entsprechenden Klimaschutzkonzeptes erfolgt. Quelle: Forschungsbericht
description: The expert opinion deals with the question whether public-sector customers may specify regional electricity (according to § 79a EEG (German Renewable Energies Act) or otherwise proven) as the object of procurement within the framework of a public procurement procedure in the sense of § 97 et seq. GWB (German Act against Restraints of Competition). The "requirement of product-neutral procurement", which follows from the competition principle under public procurement law, initially seems to contradict this. However, the principle of "regional climate neutrality" objectively justifies an exception to this requirement. In conclusion, the procurement of regional electricity by public-sector customers is therefore considered permissible under public procurement law as long as and to the extent that this is demonstrably carried out for the implementation of a corresponding climate protection concept. Quelle: Forschungsbericht
description: Das Gutachten setzt sich mit der Frage auseinander, ob öffentliche Auftraggeber im Rahmen eines Vergabeverfahrens i.S.v. § 97 ff. GWB als Beschaffungsgegenstand Regionalstrom (nach § 79a EEG oder anderweitig nachgewiesen) festlegen dürfen. Das aus dem vergaberechtlichen Wettbewerbsgrundsatz folgende „Gebot der produktneutralen Ausschreibung“ scheint dem zunächst entgegenzustehen. Allerdings rechtfertigt das Prinzip der „Regionalen Klimaneutralität“ sachlich eine Ausnahme von diesem Gebot. Im Ergebnis wird die Ausschreibung von Regionalstrom durch den öffentlichen Auftraggeber daher als vergaberechtlich zulässig angesehen, solange und soweit dies nachweislich zur Umsetzung eines entsprechenden Klimaschutzkonzeptes erfolgt.
The anti-adipogenic effect of macrophage-conditioned medium on on 3T3-L1 and human adipogenesis
Creators: name: Yarmo, Michelle Nada
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Chemistry, Biochemistry.

description: Macrophages accumulate in the adipose tissue of obese rodents and humans. We and others have reported that macrophage-secreted factors inhibit adipogenesis. This study aims to investigate the molecular mechanisms underlying this inhibitory effect. Murine 3T3-L1 preadipocytes were differentiated with medium conditioned by murine J774 macrophages (J774-MacCM) or human THP-1 macrophages (THP-1-MacCM). Clonal expansion, an early required adipogenic event, was inhibited by both MacCMs Rb phosphorylation, required for cell cycle progression, was impaired by J774-MacCM. To expand our studies to a more physiological setting, human abdominal subcutaneous preadipocytes were differentiated with THP-1-MacCM or with conditioned medium from blood monocyte-derived macrophages (MDM-CM) activated with LPS. The IKKbeta/NF-kappabeta pathway appeared to be required for the THP-1 MacCM anti-adipogenic effect. Furthermore, human preadipocytes differentiated in MDM-CM (LPS) displayed a distinct morphology, altered fibronectin expression, as well as reduced lipid accumulation and expression of adipogenic markers. These studies suggest that macrophage-secreted factors impair proximal events in the adipogenic program.
title: Estudio de las masas renales mediante mediante TC
Creators: name: Benitez Vazquez, Ana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: CT-High Resolution
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar los hallazgos radiológicos de las tumoraciones renales en el TC multidetector (TCMD) Presentar los principales aspectos técnicos del TCMD y el protocolo para el estudio de las masas renales. Discutir las ventajas que ofrece el TCMD en la...
Small systems, big challenges : Review of small drinking water system governance
Creators: name: Harris, Leila
name: McFarlane, Kiely
Publisher: name: NRC Research Press
Year: 2020

description: Small drinking water systems (SDWS) are widely identified as presenting particular challenges for drinking water management and governance in industrialised nations, due to their small customer base, geographic isolation, and limited human and financial capacity. Consequently, an increasing number and range of scholars have examined SDWS over the last 30 years. Much of this work has been technocentric in nature, focused on SDWS technologies and operations, with limited attention to how these systems are managed, governed, and situated within broader social and political-economic contexts. This review seeks to provide a comprehensive overview of the governance dimensions of SDWS by drawing together existing literature relating to SDWS governance, and exploring its key themes, research foci, and emerging directions. This overview is intended to provide guidance to scholars and practitioners interested in specific aspects of SDWS governance, and a baseline against which researchers can position future work. The review identified 117 academic articles published in English-language journals between 1990-2016 that referred to some aspect of drinking water governance in small, rural, and Indigenous communities in industrialised nations. The articles’ content and bibliographic information were analysed to identify the locations, methods, journals, and themes included in research on SDWS governance. Further analysis of SDWS’ governance dimensions is organised around four questions identified as central to SDWS research: what governance challenges are experienced by SDWS, and what are their causes, solutions, and effects? Overall, the review revealed that the SDWS governance literature is piecemeal and fragmented, with few attempts to theorise SDWS governance, or to engage in interdisciplinary, cross-jurisdictional conversations. The majority of articles examine North American SDWS, retain a technocratic orientation to drinking water governance, and are published in technical or industry journals. Such research tends to focus on the governance challenges SDWS face, and proposed solutions to systems’ performance, capacity, and regulatory challenges. A small but growing number of studies examine the causal factors underpinning these governance challenges, and their sociospatially differentiated impacts on communities. Looking forward, the review argues for a more holistic, integrative approach to research on SDWS governance, building on a water governance framework.
QSM Processing Pipeline for SWAN GE Multi-echo Data
Creators: name: Salman, Fahad
name: Schweser, Ferdinand
Publisher: name: Zenodo
Year: 2025

description: This repository contains the slurm-based QSM (and SWI) processing pipeline utilized to reconstruct susceptibility maps for SWAN GE multi-echo data at the Buffalo Neuroimaging Analysis Center, University at Buffalo.

This is a copy of the following internal code base: https://gitlab.com/schweser/mbl_swan_qsm/-/tree/v1.0_20250312?ref_type=tags (tag: v1.0_20250312; commit: f00658592816c31e49f6792e2e366f6b96979715)