cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Magnetic hybrid Pd/Fe-oxide nanoparticles meet the demands for ablative thermo-brachytherapy
Creators: name: van Oossanen, Rogier
name: Maier, Alexandra
name: Godart, Jérémy
name: Pignol, Jean-Philippe
name: Denkova, Antonia G.
name: van Rhoon, Gerard C.
name: Djanashvili, Kristina
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: To investigate the potential of hybrid Pd/Fe-oxide magnetic nanoparticles designed for thermo-brachytherapy of breast cancer, considering their specific loss power (SLP) and clinical constraints in the applied magnetic field. Hybrid nanoparticles consisting of palladium-core and iron oxide shell of increasing thickness, were suspended in water and their SLPs were measured at varying magnetic fields (12–26 mT peak) and frequencies (50–730 kHz) with a commercial alternating magnetic field generator (magneTherm™ Digital, nanoTherics Ltd.). Validation of the heating device used in this study with commercial HyperMag-C nanoparticles showed a small deviation (±4%) over a period of 1 year, confirming the reliability of the method. The integration of dual thermometers, one in the center and one at the bottom of the sample vial, allowed monitoring of homogeneity of the sample suspensions. SLPs measurements on a series of nanoparticles of increasing sizes showed the highest heating for the diameter of 21 nm (SLP = 225 W/g) at the applied frequencies of 346 and 730 kHz. No heating was observed for the nanoparticles with the size <14 nm, confirming the importance of the size-parameter. The heating ability of the best performing Pd/Fe-oxide-21 was calculated to be sufficient to ablate tumors with a radius ±4 and 12 mm using 10 and 1 mg/mL nanoparticle concentration, respectively. Nanoparticles consisting of non-magnetic palladium-core and magnetic iron oxide shell are suitable for magnetic hyperthermia/thermal ablation under clinically safe conditions of 346 kHz and 19.1 mT, with minimal eddy current effects in combination with maximum SLP.
Controproposta al ticket d’ingresso
Creators: name: Rampoldi, Stian
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 12 N. 16 (2024): Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
Ablerus promacchiae Viggiani & Ren 1993
Creators: name: Wang, Zhu Hong
name: Huang, Jian
name: Polaszek, Andrew
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Aphelinidae
Ablerus
Ablerus promacchiae

description: 10. Ablerus promacchiae Viggiani & Ren, 1993
Ablerus promacchiae Viggiani & Ren, 1993: 220.
Holotype ♀. China: Guangdong (GEIG); Paratype 1 ♀ in IEUN.
MATERIAL
No specimens examined, and originally described from Guangdong and Guangxi, China, by Viggiani & Ren (1993).
HOST
Unknown.
DISTRIBUTION
China (Guangdong, Guangxi).
REMARKS
Ablerus promacchiae resembles Ablerus macchiae (Annecke & Insley,1970) but is distinguished from the latter by the following characters: antenna with F1 not longer than F2, mid-lobe of mesoscutum with only 2 setae, narrower forewings and longer fringe (Viggiani & Ren 1993).
description: Published as part of Wang, Zhu Hong, Huang, Jian & Polaszek, Andrew, 2016, The species of genus Ablerus Howard (Hymenoptera: Chalcidoidea: Azotidae) from China, with description of a new species, pp. 395-405 in Florida Entomologist 99 (3) on page 404, DOI: 10.1653/024.099.0310, http://zenodo.org/record/11494126
Italian translation of "Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer: a plain language summary of the DESTINY-Breast03 study"
Creators: name: Cortés, Javier
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?This is a summary of a publication about the DESTINY-Breast03 study, which was published in the New England Journal of Medicine in March 2022. The study included 524 adults with advanced breast cancer that is HER2-positive, which means it has high levels of a protein called HER2. All of the participants in this study had their cancer worsen after previously receiving treatment. The treatment that was previously given to participants was a combination of a drug called trastuzumab with a type of chemotherapy called a taxane. The researchers wanted to know whether a drug called trastuzumab deruxtecan (T-DXd) could improve participants' cancer more than the standard treatment. The standard treatment is a drug called trastuzumab emtansine (T-DM1). The researchers looked at the results of this study before it was finished. This is a summary of those results.What were the results?Researchers in this study found that the risk of dying or the participants' cancer getting worse was reduced by 72% in the T-DXd group compared with the T-DM1 group. This is also called progression-free survival.79.7% of participants in the T-DXd group had their tumors shrink significantly or disappear, compared to 34.2% of those in the T-DM1 group.During the study, 10.9% of participants who received T-DXd had serious drug-related medical problems, compared to 6.1% who received T-DM1.Of the participants who received T-DXd, 10.5% experienced drug-related interstitial lung disease (ILD) or pneumonitis, compared to 1.9% of those who received T-DM1. ILD and pneumonitis are potentially serious lung problems.When the researchers first looked at the results, they could not yet be certain that T-DXd helped participants survive longer overall than T-DM1. But, when they looked at the results later in the study, they found that T-DXd did help participants to survive longer overall than T-DM1. These newer results were published separately and are not part of this summary. A link to more information about the newer results can be found at the end of this summary.What do the results mean?T-DXd gave participants a meaningful benefit overall compared to T-DM1. T-DXd could be a treatment option for people with advanced HER2-positive breast cancer that has been previously treated.
Spazi intermedi. Quali relazioni, quali esiti, quali apprendimenti
Creators: name: Cancellieri, Adriano
name: Grassi, Paola
name: Olcuire, Serena
name: Pappalardo, Giusy
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 12 N. 16 (2024): Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
Exploring the impact of insufficient thermal ablation on hepatocellular carcinoma: NDST2 overexpression mechanism and its role in facilitating growth and invasion of residual cancer cells
Creators: name: Wan, Weijun
name: Guo, Danxia
name: Kang, Tong
name: Pang, Jinshu
name: Pan, Yunjing
name: Chen, Jiamin
name: Liao, Wei
name: Chen, Yuji
name: Lin, Peng
name: Li, Lipeng
name: Yang, Hong
name: He, Yun
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Incomplete thermal ablation (ITA) fosters the malignancy of residual cells in Hepatocellular carcinoma (HCC) with unclear mechanisms now. This study aims to investigate the expression changes of NDST2 following ITA of HCC and its impact on residual cancer cells. An in vitro model of heat stress-induced liver cancer was constructed to measure the expression of NDST2 using Quantitative Real-Time PCR and Western blotting experiments. The sequencing data from nude mice were used for validation. The clinical significance of NDST2 in HCC was evaluated by integrating datasets. Gene ontology and pathway analysis were conducted to explore the potential signaling pathways regulated by NDST2. Additionally, NDST2 was knocked down in heat stress-induced HCC cells, and the effects of NDST2 on these cells were verified using Cell Counting Kit-8 assays, scratch assays, and Transwell assays. NDST2 expression levels are elevated in HCC, leading to a decrease in overall survival rates of HCC patients. Upregulation of immune checkpoint levels in high NDST2-expressing HCC may contribute to immune evasion by liver cancer cells. Additionally, the low mutation rate of NDST2 in HCC suggests a relatively stable expression of NDST2 in this disease. Importantly, animal and cell models treated with ITA demonstrate upregulated expression of NDST2. Knockdown of NDST2 in heat stress-induced liver cancer cells results in growth inhibition associated with gene downregulation. The upregulation of NDST2 can accelerate the progression of residual HCC after ITA, suggesting a potential role for NDST2 in the therapeutic efficacy and prognosis of residual HCC.
EFFECT OF CAPITAL EMPLOYED EFFICIENCY ON CORPORATE PERFORMANCE OF LISTED CONSUMER GOODS FIRMS IN NIGERIA.
Creators: name: Okoye, Jane, Frances N
name: Ezejiofor,, Raymond A
Publisher: name: SADI journals
Year: 2024
Subjects: Capital employed efficiency, Corporate Performance and Consumer goods firms

description: The study determined the effect of capital employed efficiency on the corporate performance of listed consumer goods firms in Nigeria. The study employed an ex-post facto research design. The population of this study consists of the twenty-one (21) listed consumer goods firms on the Nigerian Exchange Group. Non-probability sampling technique was deployed to determine the sample size comprising sixteen (16) listed companies. The research employed secondary data sourced from audited annual reports and accounts of the chosen companies, from 2013 to 2022. To test the hypotheses, the data were subjected to analysis using the pooled Ordinary Least Squares method. The study revealed that capital employed efficiency has a positive but insignificant effect on the return on equity of listed consumer goods firms in Nigeria. It was recommended that recognizing the positive correlation between capital employed efficiency and ROE encourages consumer goods firms in Nigeria to focus on optimizing asset utilization, managing debt levels prudently, and making strategic investment decisions to enhance overall financial performance
Ablerus williamsi
Creators: name: Wang, Zhu Hong
name: Huang, Jian
name: Polaszek, Andrew
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Aphelinidae
Ablerus
Ablerus williamsi

description: 11. Ablerus williamsi (Annecke & Insley, 1970)
Azotus williamsi Annecke & Insley, 1970: 244.
Holotype ♀. Paratypes 1 ♀, 2 ♂♂. Mauritius: Tamarin (PPRI).
Ablerus williamsi (Annecke & Insley, 1970): Hayat, 1994: 84.
MATERIAL
China. Fujian: 1 ♀, Shaxian, 1980, Nai-Quan Lin, by sweeping.
HOST
The following host has been recorded: Diaspididae: Aulacaspis tegalensis, (Annecke & Insley 1970).
DISTRIBUTION
China (Fujian), Mauritius.
description: Published as part of Wang, Zhu Hong, Huang, Jian & Polaszek, Andrew, 2016, The species of genus Ablerus Howard (Hymenoptera: Chalcidoidea: Azotidae) from China, with description of a new species, pp. 395-405 in Florida Entomologist 99 (3) on page 404, DOI: 10.1653/024.099.0310, http://zenodo.org/record/11494126
Посадка и уход за молодыми насаждениями земляники садовой
Creators: name: Павлова О.А.
name: Сорокопудов В.Н.
Publisher: name: Zenodo
Year: 2024

description: Даны рекомендации по подготовке участка для земляники, схемам посадки, уходу за растениями, а также по мерам борьбы с распространенными заболеваниями
Rhinolophus landeri Martin 1837
Creators: name: Decher, Jan
name: Hoffmann, Anke
name: Schaer, Juliane
name: N Orris, Ryan W.
name: Kadjo, Blaise
name: Astrin, Jonas
name: Monadjem, Ara
name: Hutterer, Rainer
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Rhinolophidae
Rhinolophus
Rhinolophus landeri

description: Rhinolophus landeri Martin, 1837
New material
ZFMK 2008.0282 +0283, ♀♀, W1, 3 March 2008; ZFMK 2009.0021, ♂, PF, 9 December 2008.
A total of four individuals of this common West African rhinolophid were captured, two over the creek in the W1 ravine, one at PF, and one in the WSV. One female caught at W1 on 3 March 2008 carried a 23 mm long embryo (crown-rump length). Small aggregations of this bat are most likely roosting together with other species in the cliffs, caves, and hollow trees found at the top of the W1 ravine and in the rocks on the west side of the hilltop at PF, which had already been partially clear-cut and mark- ed for bulldozing when we re-visited it in December 2008. One individual of this species was caught in a harp trap during the Pic de Fon RAP at the Banko forest site (Fahr and Ebigbo, 2004). This species roosts in caves, abandoned mines, and occasionally hollow trees or roofs (Fahr, 1996; Happold, 2013 b). At Mount Cameroon R. landeri was found at elevations up to 1,250 m (Fedden and McLeod, 1986).
Conservation status
Least Concern. Population trend is unknown (IUCN, 2015).
description: Published as part of Decher, Jan, Hoffmann, Anke, Schaer, Juliane, N Orris, Ryan W., Kadjo, Blaise, Astrin, Jonas, Monadjem, Ara & Hutterer, Rainer, 2015, Bat diversity in the Simandou Mountain Range of Guinea, with the description of a new white-winged vespertilionid, pp. 255-282 in Acta Chiropterologica 17 (2) on page 264, DOI: 10.3161/15081109ACC2015.17.2.003, http://zenodo.org/record/3943621
The Use of Evaluation Methods for Physiotherapy Treatment in Infants With Bronchiolitis—a Survey Study
Creators: name: Marforio, Sonja Andersson
name: Hansson, Eva Ekvall
name: Josenby, Annika Lundkvist
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: The aim of this study was to identify and describe methods that physiotherapists use to evaluate the immediate effects of their interventions for infants in hospital with acute respiratory tract infections. We constructed an anonymous digital survey to physiotherapists working with infants aged 0–24 months in Sweden. The survey was distributed by e-mail and posted on web pages for seven weeks, which included a reminder. Replies were obtained from 88 respondents, and 52 completed surveys remained to be analyzed. All 21 counties in Sweden were represented. The most prevalent answer options were as follows: more productive/increased or decreased cough (73%), increased oxygen saturation (35%), changed secretion sounds (33%), reduced work of breathing (20%), and parental report (16%). The physiotherapists reported to use diverse methods for evaluation of their interventions. However, to a large degree they used subjective measures, which depend on the individual clinician’s assessment and interpretation. The evaluation methods vary in psychometric properties and robustness. This study identifies the need for consensus about valid, reliable, and clinically relevant evaluation methods for this patient group.
Aotidae Elliot 1913
Creators: name: Russell A. Mittermeier
name: Anthony B. Rylands
name: Don E. Wilson
Publisher: name: Lynx Edicions
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Primates
Aotidae

description: Family AOTIDAE
(NIGHT MONKEYS)
* Small to medium-sized monkeys with small, rounded head, large, globose eyes, inconspicuous ears, white to off-white hair above eyes and around muzzle, variously distinct triradiate, black stripes on head, and long tail.
60-90 cm
vv ... z u ...
• Neotropical Region.
• Moist tropical and subtropical, submontane and montane, dry deciduous and semi-deciduous, gallery and Chacoan forests.
• 1 genus, 11 species, 13 taxa.
• 4 species Vulnerable; none Extinct since 1600.
description: Published as part of Russell A. Mittermeier, Anthony B. Rylands & Don E. Wilson, 2013, Aotidae, pp. 414-431 in Handbook of the Mammals of the World – Volume 3 Primates, Barcelona :Lynx Edicions on page 414, DOI: 10.5281/zenodo.5726960
Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
Creators: name: Cellamare, Carlo
name: Ostanel, Elena
Publisher: name: Tracce urbane. Rivista italiana transdisciplinare di studi urbani
Year: 2024

description: Tracce urbane. Rivista italiana transdisciplinare di studi urbani, V. 12 N. 16 (2024): Chi apprende da chi? Sguardi interdisciplinari tra azione pubblica e pratiche dal basso
Japanese translation of "Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer: a plain language summary of the DESTINY-Breast03 study"
Creators: name: Cortés, Javier
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?This is a summary of a publication about the DESTINY-Breast03 study, which was published in the New England Journal of Medicine in March 2022. The study included 524 adults with advanced breast cancer that is HER2-positive, which means it has high levels of a protein called HER2. All of the participants in this study had their cancer worsen after previously receiving treatment. The treatment that was previously given to participants was a combination of a drug called trastuzumab with a type of chemotherapy called a taxane. The researchers wanted to know whether a drug called trastuzumab deruxtecan (T-DXd) could improve participants' cancer more than the standard treatment. The standard treatment is a drug called trastuzumab emtansine (T-DM1). The researchers looked at the results of this study before it was finished. This is a summary of those results.What were the results?Researchers in this study found that the risk of dying or the participants' cancer getting worse was reduced by 72% in the T-DXd group compared with the T-DM1 group. This is also called progression-free survival.79.7% of participants in the T-DXd group had their tumors shrink significantly or disappear, compared to 34.2% of those in the T-DM1 group.During the study, 10.9% of participants who received T-DXd had serious drug-related medical problems, compared to 6.1% who received T-DM1.Of the participants who received T-DXd, 10.5% experienced drug-related interstitial lung disease (ILD) or pneumonitis, compared to 1.9% of those who received T-DM1. ILD and pneumonitis are potentially serious lung problems.When the researchers first looked at the results, they could not yet be certain that T-DXd helped participants survive longer overall than T-DM1. But, when they looked at the results later in the study, they found that T-DXd did help participants to survive longer overall than T-DM1. These newer results were published separately and are not part of this summary. A link to more information about the newer results can be found at the end of this summary.What do the results mean?T-DXd gave participants a meaningful benefit overall compared to T-DM1. T-DXd could be a treatment option for people with advanced HER2-positive breast cancer that has been previously treated.
The Effect of Mobility Assistance Dogs on Quality of Life in Children with Physical and Neurological Impairments
Creators: name: Curtin, Heather
name: Simms, Ciaran K.
name: Kiernan, Damien
name: Reilly, Richard B.
name: Spirtos, Michelle
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: To measure the quality of life in children with impaired walking who receive a mobility assistance dog (MAD). The parents of ten children who received a MAD completed the cerebral palsy quality of life questionnaire, before receiving their dog and at one, three, and six-month follow-up. Data were analyzed to assess changes for each participant and to the group. The group showed a positive change in the domains of social well-being and acceptance, feelings about functioning, and emotional well-being and self-esteem after six months. Children with less impairment (GMFCS I–II) showed a change in social-wellbeing and acceptance, feelings about functioning, participation, physical health, and emotional-wellbeing and self-esteem after six months. Children with more impairment (GMFCS III–IV) showed no change at any timepoint measured. This novel therapeutic area of receiving a MAD demonstrated some positive quality of life changes after six months for a small group of children with impaired walking. These are preliminary findings in a small sample and this intervention would benefit from further study.
Bimanual Coordination in Children with Bilateral Cerebral Palsy: A Cross-Sectional Study
Creators: name: Herard, Grace-Anne M.
name: Hung, Ya-Ching
name: Brandao, Marina B.
name: Gordon, Andrew M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: To compare bimanual coordination in children with bilateral cerebral palsy (BCP) with that of children with typical development (TD) and correlate bimanual coordination with clinical measures of hand function. 3-D kinematic data were collected from 14 children with BCP (mean age 13 years 1 month; range 7.3–17.2 years, 5 females) and 14 age-matched children with TD (mean age 13 years 1 month, range 7.0–16.0 years, 7 females) as they opened a drawer with one hand and activated a switch inside it with the other hand at self-paced and as-fast-as-possible speeds. Hand roles varied in each condition. Participants' hand function levels were classified using the Manual Ability Classification System. Unimanual dexterity and bimanual performance were evaluated using the Box and Blocks Test and Both Hands Assessment respectively. Participants with BCP performed the bimanual task more slowly (p < 0.001) and sequentially, as evidenced by greater time differences between the two hands achieving the end goal (p = 0.01). Faster speeds, particularly when the less affected hand opened the drawer, facilitated time-related measures of bimanual coordination (p < 0.05). Bimanual coordination correlated with all clinical measures of hand function (p < 0.05). For children with BCP, speed and hand used for each subcomponent of the task influence bimanual coordination. Better bimanual coordination is associated with less impairment of both hands.
Society of Research Software Engineering AGM 2024
Creators: name: Society of Research Software Engineering
Publisher: name: Zenodo
Year: 2025
Subjects: rse

description: The 2024 Annual General Meeting of the Society of Research Software Engineering will be held at 17:15 – 18:15 on Wednesday 4th September 2024 in G.41, Frederick Douglass Centre, Newcastle University, UK as part of RSECon24.

The purpose of the AGM is for the trustees to update the Society’s members on what we have been doing this year to develop the Society and further our shared aims, and for members, to vote on specific resolutions and to have the opportunity to ask questions and raise topics for future consideration. No member resolutions have been put forward to be voted upon during the AGM but we will be announcing the election of new trustees as described below.

More information can be found athttps://society-rse.org/society-agm-2024/
Evaluation of magnetic resonance thermometry performance during MR-guided hyperthermia treatment of soft-tissue sarcomas in the lower extremities and pelvis
Creators: name: Karkavitsas, Spyridon N.
name: Göger-Neff, Marianne
name: Kawula, Maria
name: Sumser, Kemal
name: Zilles, Benjamin
name: Wadepohl, Martin
name: Landry, Guillaume
name: Kurz, Christopher
name: Kunz, Wolfgang G.
name: Dietrich, Olaf
name: Lindner, Lars H.
name: Paulides, Margarethus M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: This study evaluated the performance of magnetic resonance thermometry (MRT) during deep-regional hyperthermia (HT) in pelvic and lower-extremity soft-tissue sarcomas. 17 pelvic (45 treatments) and 16 lower-extremity (42 treatments) patients underwent standard regional HT and chemotherapy. Pairs of double-echo gradient-echo scans were acquired during the MR protocol 1.4 s apart. For each pair, precision was quantified using phase data from both echoes (‘dual-echo’) or only one (‘single-echo’) in- or excluding body fat pixels in the field drift correction region of interest. The precision of each method was compared to that of the MRT approach using a built-in clinical software tool (SigmaVision). Accuracy was assessed in three lower-extremity patients (six treatments) using interstitial temperature probes. The Jaccard coefficient quantified pretreatment motion; receiver operating characteristic analysis assessed its predictability for acceptable precision (<1 °C) during HT. Compared to the built-in dual-echo approach, single-echo thermometry improved the mean temporal precision from 1.32 ± 0.40 °C to 1.07 ± 0.34 °C (pelvis) and from 0.99 ± 0.28 °C to 0.76 ± 0.23 °C (lower extremities). With body fat-based field drift correction, single-echo mean accuracy improved from 1.4 °C to 1.0 °C. Pretreatment bulk motion provided excellent precision prediction with an area under the curve of 0.80–0.86 (pelvis) and 0.81–0.83 (lower extremities), compared to gastrointestinal air motion (0.52–0.58). Single-echo MRT exhibited better precision than dual-echo MRT. Body fat-based field-drift correction significantly improved MRT accuracy. Pretreatment bulk motion showed improved prediction of acceptable MRT temporal precision over gastrointestinal air motion.
Portuguese translation of "Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer: a plain language summary of the DESTINY-Breast03 study"
Creators: name: Cortés, Javier
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?This is a summary of a publication about the DESTINY-Breast03 study, which was published in the New England Journal of Medicine in March 2022. The study included 524 adults with advanced breast cancer that is HER2-positive, which means it has high levels of a protein called HER2. All of the participants in this study had their cancer worsen after previously receiving treatment. The treatment that was previously given to participants was a combination of a drug called trastuzumab with a type of chemotherapy called a taxane. The researchers wanted to know whether a drug called trastuzumab deruxtecan (T-DXd) could improve participants' cancer more than the standard treatment. The standard treatment is a drug called trastuzumab emtansine (T-DM1). The researchers looked at the results of this study before it was finished. This is a summary of those results.What were the results?Researchers in this study found that the risk of dying or the participants' cancer getting worse was reduced by 72% in the T-DXd group compared with the T-DM1 group. This is also called progression-free survival.79.7% of participants in the T-DXd group had their tumors shrink significantly or disappear, compared to 34.2% of those in the T-DM1 group.During the study, 10.9% of participants who received T-DXd had serious drug-related medical problems, compared to 6.1% who received T-DM1.Of the participants who received T-DXd, 10.5% experienced drug-related interstitial lung disease (ILD) or pneumonitis, compared to 1.9% of those who received T-DM1. ILD and pneumonitis are potentially serious lung problems.When the researchers first looked at the results, they could not yet be certain that T-DXd helped participants survive longer overall than T-DM1. But, when they looked at the results later in the study, they found that T-DXd did help participants to survive longer overall than T-DM1. These newer results were published separately and are not part of this summary. A link to more information about the newer results can be found at the end of this summary.What do the results mean?T-DXd gave participants a meaningful benefit overall compared to T-DM1. T-DXd could be a treatment option for people with advanced HER2-positive breast cancer that has been previously treated.
Russian translation of "Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer: a plain language summary of the DESTINY-Breast03 study"
Creators: name: Cortés, Javier
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?This is a summary of a publication about the DESTINY-Breast03 study, which was published in the New England Journal of Medicine in March 2022. The study included 524 adults with advanced breast cancer that is HER2-positive, which means it has high levels of a protein called HER2. All of the participants in this study had their cancer worsen after previously receiving treatment. The treatment that was previously given to participants was a combination of a drug called trastuzumab with a type of chemotherapy called a taxane. The researchers wanted to know whether a drug called trastuzumab deruxtecan (T-DXd) could improve participants' cancer more than the standard treatment. The standard treatment is a drug called trastuzumab emtansine (T-DM1). The researchers looked at the results of this study before it was finished. This is a summary of those results.What were the results?Researchers in this study found that the risk of dying or the participants' cancer getting worse was reduced by 72% in the T-DXd group compared with the T-DM1 group. This is also called progression-free survival.79.7% of participants in the T-DXd group had their tumors shrink significantly or disappear, compared to 34.2% of those in the T-DM1 group.During the study, 10.9% of participants who received T-DXd had serious drug-related medical problems, compared to 6.1% who received T-DM1.Of the participants who received T-DXd, 10.5% experienced drug-related interstitial lung disease (ILD) or pneumonitis, compared to 1.9% of those who received T-DM1. ILD and pneumonitis are potentially serious lung problems.When the researchers first looked at the results, they could not yet be certain that T-DXd helped participants survive longer overall than T-DM1. But, when they looked at the results later in the study, they found that T-DXd did help participants to survive longer overall than T-DM1. These newer results were published separately and are not part of this summary. A link to more information about the newer results can be found at the end of this summary.What do the results mean?T-DXd gave participants a meaningful benefit overall compared to T-DM1. T-DXd could be a treatment option for people with advanced HER2-positive breast cancer that has been previously treated.
Paraqianlabeo Zhao, Sullivan, Zhang & Peng, 2014, new genus
Creators: name: Zhao, Hai-Tao
name: Sullivan, John P.
name: Zhang, Yao-Guang
name: Peng, Zuo-Gang
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Cypriniformes
Cyprinidae
Paraqianlabeo

description: Paraqianlabeo, new genus
Type species: Paraqianlabeo lineatus, new species (Figs. 2, 4)
Diagnosis. Paraqianlabeo can be distinguished from all other genera of the Garraina (sensu Stiassny & Getahun 2007) by its uniquely modified oromandibular morphology; i.e., arched, wide, rudimentary sucker formed by raised front and lateral margins of lower lip, postlabial groove and mental groove between middle and lateral lobes of lower lip chevron-shaped (Fig. 2). The genus is further distinguished by having a unique combination of the following characters: anteroventral margin of rostral cap arched, thin and papillose; rostral cap not overlying upper lip, upper lip connected with lower lip around corners of mouth; well developed upper lip free from upper jaw; lower lip divided into two lateral fleshy lobes and one central plate, these two lateral fleshy lobes small and short, median lobe of lower lip large; anterior and anterolateral edges of upper and lower lip finely papillose; shallow, straight groove between lower lip and lower jaw; lower jaw bearing thin, cornified cutting edge; scales in ventral medial region from pectoral fins to pelvic fins half-hidden and subcutaneous; 3 scale rows below lateral line; 7½-8 branched dorsal-fin rays.
Etymology. The generic name is from a combination of the Latin word Para (beside; beyond or outside; associated with) and Qian (abbreviation for Guizhou Province), where the type species was collected, and the Latin word Labeo, a generic name and commonly utilized suffix for Labeoninae genera. Gender: masculine.
Specimen Voucher Locality GenBank Source No.
Ingroup
JX074207
Osteochilus salsburyi IHBCY0308001 China: Rong’an, Guangxi HM536883 Yang & Mayden (2010) Stenorynchoacrum xijian- KIZDLN20080001 China: Guilin, Guangxi GU086597 Zheng et al. (2010)
gensis
Sinocrossocheilus labia- KIZZLP20090021 GU086596 Zheng et al. (2010)
tus China: Tongzi, Guizhou
description: Published as part of Zhao, Hai-Tao, Sullivan, John P., Zhang, Yao-Guang & Peng, Zuo-Gang, 2014, Paraqianlabeo lineatus, a new genus and species of labeonine fishes (Teleostei: Cyprinidae) from South China, pp. 257-270 in Zootaxa 3841 (2) on pages 259-260, DOI: 10.11646/zootaxa.3841.2.5, http://zenodo.org/record/230269
Long-term re-intervention after USgHIFU and prediction of NPVR in different ages of patients with uterine fibroids
Creators: name: Li, Shuang
name: Ma, Wang-wa
name: Yang, Mei-Jie
name: Deng, Yong-Bin
name: Hu, Liang
name: Chen, Jin-Yun
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Long-term re-intervention after ultrasound-guided high intensity focused ultrasound (USgHIFU) ablation was reported, and the prediction of non-perfusion volume ratio (NPVR) in differently aged patients with uterine fibroids (UFs) was explored. Patients with UFs who underwent USgHIFU ablation from January 2012 to December 2019 were enrolled and divided into < 40-year-old and ≥ 40-year-old groups. Cox regression was used to analyze the influencing factors of re-intervention rate, and receiver operating characteristic (ROC) curve was used to analyze the correlation between NPVR and re-intervention rate. A total of 2141 patients were enrolled, and 1558 patients were successfully followed up. The 10-year cumulative re-intervention rate was 21.9%, and the < 40-year-old group had a significantly higher rate than the ≥ 40-year-old group (30.8% vs. 19.1%, p < 0.001). NPVR was an independent risk factor in both two groups. When the NPVR reached 80.5% in the < 40-year-old group and 75.5% in the ≥ 40-year-old group, the risk of long-term re-intervention was satisfactory. The long-term outcome of USgHIFU is promising. The re-intervention rate is related to NPVR in differently aged patients. Young patients need a high NPVR to reduce re-intervention risk.
Tetramorium hungaricum Roszler 1935
Creators: name: Kiran, Kadri
name: Karaman, Celal
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Tetramorium
Tetramorium hungaricum

description: Tetramorium hungaricum Röszler, 1935 **
Tetramorium caespitum subsp. hungarica Röszler, 1935: 78.
MATERIAL EXAMINED. — Turkey • 2 ☿; Bursa, Gemlik, Narlı Vill.; 40°28’53”N, 29°01’26”E; 350 m; 14.VIII.1998; K. Kiran leg.; EMTU K98 /0633 • 1 ☿; Denizli, Irlıganlı Town; 37°53’488”N, 29°11’647”E; 465 m; 11.VIII.2014; C. Karaman leg.; EMTU 07 /2197c • 8 ☿; İstanbul, Şile, Ağva; 41°08’N, 29°51’E; 0 m; 20.VIII.2012; C. Karaman leg.; EMTU 12 /0059 • 50 ☿; Kütahya; 39°12’22”N, 30°08’27”E; 1300 m; 13. VI.2004; K. Kiran leg.; EMTU 04 /0179 • 1 ☿; same collection data as for preceding; K. Kiran leg.; EMTU 04 /0184c • 20 ☿; Manisa, Köprübaşı, Kurtlar Vill.; 38°43’N, 28°17’E; 600 m; 10.VIII.2014; C. Karaman leg.; EMTU 07 /2115a.
DISTRIBUTION IN TURKEY. — Kırklareli. First record from Asia continent.
description: Published as part of Kiran, Kadri & Karaman, Celal, 2020, Additions to the Ant Fauna of Turkey (Hymenoptera, Formicidae), pp. 285-329 in Zoosystema 42 (18) on page 320, DOI: 10.5252/zoosystema2020v42a18, http://zenodo.org/record/3922267
title: Climate and society during the Late Bronze Age-Early Iron Age transition in the Eastern Mediterranean
Creators: name: Bowler, Lydia
Publisher: name: University of Reading
Year: 2024

description: During the 13th and 12th centuries BCE, the prosperous Late Bronze Age (LBA) came to 
an end across the eastern Mediterranean (EM). At this time, the EM saw the destruction 
and abandonment of important sites and the demise of once-powerful Empires and 
state systems. Following the events of the terminal LBA, the EM entered the Early Iron 
Age (EIA), which saw political fragmentation and cultural devolution. Proposed 
explanations for the end of the LBA are contentious and subject to debate. In recent 
decades, the climate change hypothesis, which proposes that climate change triggered 
the events of the LBA-EIA transition through widespread drought and food shortages, 
has become popular, with several EM palaeoclimate records identifying an onset of 
drier and cooler conditions at ca. 3.2 ka BP. However, this theory is subject to several 
limitations, and so this thesis has sought to provide a nuanced re-examination of the 
role of climate on the LBA-EIA transition. 
This interdisciplinary thesis presents an examination of climate and society across the 
EM through the analysis of key palaeoclimate proxy data and archaeological evidence. 
Through the examination of a new highly resolved stable isotope record from Kocain 
Cave in Türkiye and existing palaeoclimate proxy records from the EM and surrounding 
areas, we can identify a shift to drier and cooler conditions in several proxy records 
around 3.2 ka BP, coinciding with the LBA-EIA transition. However, heterogeneity can be 
identified in climatic and socio-political conditions across the EM. Whilst climate 
changes may have contributed to the end of the Hittite Empire and Mycenaean Palatial 
System, there is no simple cause-and-effect relationship between climate and the LBA-EIA transition across the EM, as has been presented by the existing climate hypothesis. 
The climate hypothesis, therefore, requires significant amendments in order to address 
the heterogeneity of EM climate and society.
Spanish translation of "Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer: a plain language summary of the DESTINY-Breast03 study"
Creators: name: Cortés, Javier
Publisher: name: Taylor & Francis
Year: 2024

description: What is this summary about?This is a summary of a publication about the DESTINY-Breast03 study, which was published in the New England Journal of Medicine in March 2022. The study included 524 adults with advanced breast cancer that is HER2-positive, which means it has high levels of a protein called HER2. All of the participants in this study had their cancer worsen after previously receiving treatment. The treatment that was previously given to participants was a combination of a drug called trastuzumab with a type of chemotherapy called a taxane. The researchers wanted to know whether a drug called trastuzumab deruxtecan (T-DXd) could improve participants' cancer more than the standard treatment. The standard treatment is a drug called trastuzumab emtansine (T-DM1). The researchers looked at the results of this study before it was finished. This is a summary of those results.What were the results?Researchers in this study found that the risk of dying or the participants' cancer getting worse was reduced by 72% in the T-DXd group compared with the T-DM1 group. This is also called progression-free survival.79.7% of participants in the T-DXd group had their tumors shrink significantly or disappear, compared to 34.2% of those in the T-DM1 group.During the study, 10.9% of participants who received T-DXd had serious drug-related medical problems, compared to 6.1% who received T-DM1.Of the participants who received T-DXd, 10.5% experienced drug-related interstitial lung disease (ILD) or pneumonitis, compared to 1.9% of those who received T-DM1. ILD and pneumonitis are potentially serious lung problems.When the researchers first looked at the results, they could not yet be certain that T-DXd helped participants survive longer overall than T-DM1. But, when they looked at the results later in the study, they found that T-DXd did help participants to survive longer overall than T-DM1. These newer results were published separately and are not part of this summary. A link to more information about the newer results can be found at the end of this summary.What do the results mean?T-DXd gave participants a meaningful benefit overall compared to T-DM1. T-DXd could be a treatment option for people with advanced HER2-positive breast cancer that has been previously treated.
Neillia D. Don
Creators: name: Pendry, Colin A.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rosaceae
Neillia

description: Key to the species in Nepal
1a. Inflorescence an open panicle to 14 cm overall, with side branches of similar length to main axis. At anthesis flowers 3–6 mm apart ....................................................................................................................................... N. thyrsiflora
1b. Inflorescence a compact raceme to 6 cm overall, rarely with up to 5 distinctly shorter branches at base. At anthesis flowers 1–4 mm apart. .................................................................................................................................................. 2
2a. Ovary villous. Leaves villous above and below, velvety to the touch. ........................................................ N. velutina
2b. Ovary glabrous. Leaves glabrous or sparsely hairy above and below, not velvety to the touch. ............... N. rubiflora
description: Published as part of Pendry, Colin A., 2010, A new species of Neillia (Rosaceae) from Bhutan and eastern Nepal, pp. 38-40 in Phytotaxa 10 on page 40, DOI: 10.11646/phytotaxa.10.1.5, http://zenodo.org/record/4899750
Gold nanobipyramids-based laser-activated sealants for effective skin sealing and repair
Creators: name: Pallod, Shubham
name: Fuller, Gareth
name: Chowdhury, Trishita
name: Rege, Kaushal
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Computational Biology

description: Anisotropic gold nanostructures have gained increased attention for biomedical applications because of their remarkable optical properties. An emerging type of gold nanostructure—gold nanobipyramids (AuNBP)—has been shown to exhibit superior absorption properties compared to conventionally used gold nanoparticles, which makes them attractive for photothermal applications. We generated a high-shape-purity dispersion of AuNBP using a seed-mediated method and embedded them as photothermal conversion agents in a silk fibroin matrix to investigate their efficacy in photothermal sealing of incisional wounds in immunocompetent mice. These AuNBP-doped laser-activated sealants, or AuNBP-LASE were able to absorb near-infrared laser energy and convert it to heat, thereby inducing transient hyperthermia in the wound and the surrounding tissue. This photothermal conversion facilitated rapid sealing of the skin tissue by the AuNBP-LASE, which resulted in faster functional recovery of skin barrier function compared to nylon sutures at the early stages of repair. Further, the biomechanical properties of the healing skin closed with AuNBP-LASE those of intact skin more rapidly compared to incisions approximated with sutures. Histology studies indicated higher penetration of the LASE within the volume of the incision in skin tissue, lower scab formation, and a similar epidermal gap compared to conventional suturing. These results demonstrate that AuNBP-LASEs can be effective as wound approximation devices for photothermal sealing.
Tetramorium inerme Mayr 1877
Creators: name: Kiran, Kadri
name: Karaman, Celal
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Tetramorium
Tetramorium inerme

description: Tetramorium inerme Mayr, 1877
Tetramorium caespitum var. inerme Mayr, 1877: 17.
MATERIAL EXAMINED. — Turkey • 4 ☿; Şanlıurfa, Harran; 36°52’N, 39°01’E; 24.IV.2015; C. Karaman leg.; EMTU 15 /0009a.
DISTRIBUTION IN TURKEY. — Turkey?
REMARKS
Tetramorium inerme is distributed in Kazakhstan, Turkmenistan, Armenia, Azerbaijan, Iran and Caucasus (Mayr 1877, 1880; Paknia et al. 2008; Borowiec 2014). Borowiec (2014) noted this species also from Turkey without indicating an exact locality. This species was collected in locality along the border with Syria.
description: Published as part of Kiran, Kadri & Karaman, Celal, 2020, Additions to the Ant Fauna of Turkey (Hymenoptera, Formicidae), pp. 285-329 in Zoosystema 42 (18) on page 320, DOI: 10.5252/zoosystema2020v42a18, http://zenodo.org/record/3922267
Time series analysis combined with transcriptome sequencing to explore characteristic genes and potential molecular mechanisms associated with ultrasound-guided microwave ablation of glioma
Creators: name: Zhang, Qian
name: Yang, Guangfei
name: Chang, Ruijiao
name: Wang, Fuxia
name: Han, Tao
name: Tian, Jin
name: Wang, Wen
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: This study aimed to explore marker genes and their potential molecular mechanisms involved in US-guided MWA for glioma in mice. The differentially expressed genes (DEGs1 and DEGs2) and lncRNAs (DELs1 and DELs2) were obtained between Non (glioma tissues without MWA) and T0 groups (0h after MWA), as well as between Non and T24 groups (24h after MWA). The down-regulation cluster genes (CONDOWNDEGs) and upregulation cluster genes (CONUPDEGs) were identified by time series analysis. Candidate genes were obtained by overlapping CONDOWNDEGs with downregulation DEGs (DOWNDEGs)1 and DOWNDEGs2, as well as CONUPDEGs with up-regulation DEGs (UPDEGs)1 and UPDEGs2. The expressions of immune checkpoints and inflammatory factors, gene set enrichment analysis (GSEA), and protein subcellular localization were performed. The eXpression2Kinases (X2K), GeneMANIA, transcription factor (TF), and competing endogenous (ce) RNA regulatory networks were conducted. The expression of marker genes was validated by quantitative real-time polymerase chain reaction (qRT-PCR). Five marker genes (IL32, VCAM1, IL34, NFKB1 and CXCL13) were identified, which were connected with immune-related functions. Two immune checkpoints (CD96 and TIGIT) and six inflammatory factors played key roles in US-guided MWA for glioma. ceRNA regulatory networks revealed that miR-625-5p, miR-625-3p, miR-31-5p and miR-671-5p were associated with target genes. qRT-PCR indicated both IL32, VCAM1, and NFKB1 were potential markers under US-guided MWA-related time series analysis. The use of US-guided MWA might be a practical method for influencing the function of target genes, regulating time frames to decrease inflammation, and stimulating immune responses in glioma therapy.