cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
CD-loop Extension in Zika Virus Envelope Protein Key for Stability and Pathogenesis
Creators: name: Ng, Thiam-Seng
name: Lim, Elisa X.Y.
name: Lok, Shee-Mei
name: Lim, Xin-Ni
name: Gallichotte, Emily N.
name: Baric, Ralph S.
name: Dinnon III, Kenneth H.
name: Menachery, Vineet D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: With severe disease manifestations including microcephaly, congenital malformation, and Guillain-Barré syndrome, Zika virus (ZIKV) remains a persistent global public health threat. Despite antigenic similarities with dengue viruses, structural studies have suggested the extended CD-loop and hydrogen-bonding interaction network within the ZIKV envelope protein contribute to stability differences between the viral families. This enhanced stability may lead to the augmented infection, disease manifestation, and persistence in body fluids seen following ZIKV infection. To examine the role of these motifs in infection, we generated a series of ZIKV recombinant viruses that disrupted the hydrogen-bonding network (350A, 351A, and 350A/351A) or the CD-loop extension (Δ346). Our results demonstrate a key role for the ZIKV extended CD-loop in cell-type-dependent replication, virion stability, and in vivo pathogenesis. Importantly, the Δ346 mutant maintains similar antigenicity to wild-type virus, opening the possibility for its use as a live-attenuated vaccine platform for ZIKV and other clinically relevant flaviviruses.
"Die wahre Entdeckung Amerikas steht noch in den Anfängen"
Creators: name: Rodríguez Maradiaga, Oscar Andrés
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 46 Nr. 1 (1992): Herder Korrespondenz, Band 46, Heft 1
Πτυχές του καθημερινού βίου των μοναχών στο «Λειμωνάριον» του Ιωάννου Μόσχου
Creators: name: Κατσικλή, Μαρία Αφροδίτη Ηλία
Publisher: name: Aristotle University of Thessaloniki
Year: 2025
Subjects: Μοναχική ζωή
Ασκητική παράδοση
Πνευματικές διηγήσεις
Ασκητές
Θαύματα
Καθημερινός βίος
Πνευματικότητα
Προσευχή
Παλαιστινιακή έρημος
Ψυχοφελείς διηγήσεις
Έρημος
Λαύρα
Ησυχαστής
Αββάς
Διήγηση
Κοινόβιο
Αναχωρητής
Monastic life
Ascetic tradition
Spiritual narratives
Hermits
Miracles
Daily life
Spirituality
Prayer
Palestinian desert
Spiritually beneficial stories
Desert
Lavra
Hesychast
Abbot
Narrative
Coenobium
Anchorite

description: Το έργο «Λειμωνάριο» του Ιωάννη Μόσχου, το οποίο αποτελεί μια σημαντική συλλογή πνευματικών διηγήσεων και βιογραφικών σημειωμάτων μοναχών και ερημιτών της Ανατολής τον 6ο και 7ο αιώνα. Ο Ιωάννης Μόσχος, με τη βοήθεια του μαθητή του, Σωφρόνιου, συνέταξε αυτό το έργο, καταγράφοντας μαρτυρίες και περιστατικά που αντικατοπτρίζουν την πνευματική ζωή και τις δοκιμασίες της ασκητικής παράδοσης. Το σύγγραμμα προσφέρει ηθικά και πνευματικά διδάγματα μέσα από σύντομες αφηγήσεις που περιγράφουν τον αγώνα των μοναχών για αυτοπειθαρχία και αφοσίωση στην προσευχή, καθώς και την καθημερινότητά τους. Το έργο περιλαμβάνει επίσης θαύματα και διδαχές που αναδεικνύουν τις πνευματικές αξίες της εποχής. Η γραφή του Μόσχου είναι απλή και προσιτή, με στόχο να μεταφέρει πνευματικά διδάγματα τόσο σε μοναχούς όσο και σε λαϊκούς. Ο σκοπός της μελέτης εστιάζει στην καταγραφή της καθημερινότητας των μοναζόντων και η διερεύνηση της ζωής τους σε όλες τις εκφάνσεις και τις αλληλεπιδράσεις που θα μπορούσε να έχει.
description: The work Leimonarion by John Moschus is a significant collection of spiritual narratives and biographical notes about monks and hermits of the East during the 6th and 7th centuries. John Moschus, with the assistance of his disciple Sophronius, compiled this work, documenting accounts and incidents that reflect the spiritual life and the challenges of the ascetic tradition. The text offers moral and spiritual lessons through brief stories that describe the monks' struggle for self-discipline and dedication to prayer, as well as their daily lives. The work also includes miracles and teachings that highlight the spiritual values of the era. Moschus' writing is simple and accessible, aiming to convey spiritual lessons to both monks and laypeople. The purpose of this study focuses on documenting the daily life of monastics and exploring their existence in all its aspects and interactions that it might encompass.
description: Μεταπτυχιακό σε συνεργασία με το Τμήμα Κοινωνικής Θεολογίας και Θρησκειολογίας του Εθνικού και Καποδιστριακού Πανεπιστημίου Αθηνών
For Partial Fulfillment of the Requirements of the Degree of Master in Business Administration in Management
Creators: name: Mustefa Muhammed
Publisher: name: Zenodo
Year: 2014

description: Effective supply chain management (SCM) has become a potentially valuable way of securing competitive advantage through enhancing operational and improving organizational performances since competition is no longer between organizations, but among supply chains. This research conceptualizes and develops five dimensions of SCM practice (strategic supplier partnership, customer relationship, level of information sharing, quality of information sharing, and internal lean practices) and tests the relationships between SCM practices, operational performance, and organizational performance. The data for the study was collected from 42 employees of Awash tannery Plc. The relationships proposed in the framework were tested using Pearson correlation, and the causal relations were analyzed using regression analysis. From the result of the analysis it is concluded that there is strong relationship between SCM practices, operational performance and organizational performance. Besides, SCM practices have an influence both on operational performance and organizational performance. On the other hand, operational performance has also an influence on organizational performance. Therefore, in order to achieve advancement in marketing and financial performance in the long-run through enhancing organizational performance, it is better for the organization to give due emphasis to the constructs of SCM practices and the measures of operational performance.
Multilingualism and Psychosis: A Scoping Review
Creators: name: Hodgins, Vegas
name: Mouslih, Chaimaa
name: Rukh-E-Qamar, Hani
name: Titone, Debra
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Linguistics
subject: FOS: Languages and literature
subject: Psychiatry and Psychology
subject: Medicine and Health Sciences
subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: bilingualism
subject: delusion
subject: hallucination
subject: multilingualism
subject: psychosis
subject: schizoaffective disorder
subject: schizophrenia
subject: scoping review

description: The proposed scoping review aims to gather the literature on (1) the modulating impact of L1/L2 social or situational context on language usage in people with psychosis, (2) the impact of multilingualism on symptom expression in individuals with psychosis, and (3) specific struggles faced by multilinguals with psychosis in navigating social and healthcare systems. In this way, we hope to synthesize the literature from a (1) psycholinguistic, (2) phenomenological, and (3) sociological perspective.
"Die Orthodoxie bleibt Struktur und Lehre der ungeteilten Kirche treu"
Creators: name: Papandreu, Damaskēnos
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 46 Nr. 1 (1992): Herder Korrespondenz, Band 46, Heft 1
Energy-Tunable Quantum Dot with Minimal Fine Structure Created by Using Simultaneous Electric and Magnetic Fields
Creators: name: Pooley, M. A.
name: Bennett, A. J.
name: Stevenson, R. M.
name: Shields, A. J.
name: Farrer, I.
name: Ritchie, D. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The neutral biexciton cascade of single quantum dots is a promising source of entangled photon pairs. The character of the entangled state is determined by the energy difference between the excitonic eigenstates known as fine-structure splitting (FSS). Here we reduce the magnitude of the FSS by simultaneously using two independent tuning mechanisms: in-plane magnetic field and vertical electric field. We observe that there exists a minimum possible FSS in each quantum dot which is independent of these tuning mechanisms. However, with simultaneous application of electric and magnetic fields, we show the FSS can be reduced to its minimum value as the energy of emission is tuned over several meV with a 5-T magnet.
Assessment of Somatosensory and Motor Processing Time in Retired Athletes with a History of Repeated Head Trauma
Creators: name: Pearce, Alan
name: King, D
name: Kidgell, DJ
name: Frazer, Ashlyn
name: Tommerdahl, M
name: Suter, CM
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 5204
subject: Cognitive and computational psychology
classificationCode: 4207
subject: Sports science and exercise
classificationCode: 420703
subject: Motor control
classificationCode: 3209
subject: Neurosciences
subject: FOS: Clinical medicine
classificationCode: 4201
subject: Allied health and rehabilitation science

description: Measurement of the adverse outcomes of repeated head trauma in athletes is often achieved using tests where the comparator is ‘accuracy’. While it is expected that ex-athletes would perform worse than controls, previous studies have shown inconsistent results. Here we have attempted to address these inconsistencies from a different perspective by quantifying not only accuracy, but also motor response times. Age-matched control subjects who have never experienced head trauma (n = 20; 41.8 ± 14.4 years) where compared to two cohorts of retired contact sport athletes with a history of head trauma/concussions; one with self-reported concerns (n = 36; 45.4 ± 12.6 years), and another with no ongoing concerns (n = 19; 43.1 ± 13.5 years). Participants performed cognitive (Cogstate) and somatosensory (Cortical Metrics) testing with accuracy and motor times recorded. Transcranial magnetic stimulation (TMS) investigated corticospinal conduction and excitability. Results showed that there was little difference between groups in accuracy scores. Conversely, motor times in all but one test revealed that ex-athletes with self-reported concerns were significantly slower compared to other groups (p ranges 0.031 to <0.001). TMS latency showed significantly increased time (p = 0.008) in the group with ongoing concerns. These findings suggest that incorporating motor times is more informative than considering accuracy scores alone.
Emergence of novel human norovirus GII.17 strains correlates with changes in blockade antibody epitopes
Creators: name: Donaldson, Eric F.
name: Baric, Ralph S.
name: Debbink, Kari
name: Swann, Excel W.
name: Mallory, Michael L.
name: Lindesmith, Lisa C.
name: Kocher, Jacob F.
name: Brewer-Jensen, Paul D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Background
Human norovirus is a significant public health burden, with >30 genotypes causing endemic levels of disease and strains from the GII.4 genotype causing serial pandemics as the virus evolves new ligand binding and antigenicity features. During 2014–2015, genotype GII.17 cluster IIIb strains emerged as the leading cause of norovirus infection in select global locations. Comparison of capsid sequences indicates that GII.17 is evolving at previously defined GII.4 antibody epitopes.

Methods
Antigenicity of virus-like particles (VLPs) representative of clusters I, II, and IIIb GII.17 strains were compared by a surrogate neutralization assay based on antibody blockade of ligand binding.

Results
Sera from mice immunized with a single GII.17 VLP identified antigenic shifts between each cluster of GII.17 strains. Ligand binding of GII.17 cluster IIIb VLP was blocked only by antisera from mice immunized with cluster IIIb VLPs. Exchange of residues 393–396 from GII.17.2015 into GII.17.1978 ablated ligand binding and altered antigenicity, defining an important varying epitope in GII.17.

Conclusions
The capsid sequence changes in GII.17 strains result in loss of blockade antibody binding, indicating that viral evolution, specifically at residues 393–396, may have contributed to the emergence of cluster IIIb strains and the persistence of GII.17 in human populations.
Critical analysis of the philosophical conception of verification of being/the self in Heidegger's “Being and Time” against dao/the other in Laozi's Daodejing.
Creators: name: Green, Lucian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Arts and Humanities

description: That dao and being are correct as written about by Laozi and Heidegger respectively is exposed through eight perspectival points of verificationalism (which is correct because of the connectionism present in texts), connectionism present in texts, communication (which is correct because of the professional development of the other), professional development of the other, articulation (which is correct because of economic role-earning), accreditation, universalisation, and mimickry of nature. I aimed to model the verification of Heidegger’s ontology with Laozi’s nothingness on business, education and having children with humanist pedagogy. I will examine the magna opera Laozi’s “Daodejing” and Heidegger’s “Being and Time”.
Dissecting antibodies induced by a chimeric yellow fever-dengue, live-attenuated, tetravalent dengue vaccine (CYD-TDV) in naive and dengue-exposed individuals
Creators: name: Baric, Ralph
name: Bonaparte, Matthew
name: Jackson, Nicholas
name: Henein, Sandra
name: Shaik, S. Farzana
name: Swanstrom, Jesica
name: de Silva, Aravinda M.
name: Byers, Anthony M.
name: Guy, Bruno
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Sanofi Pasteur has developed a chimeric yellow feverÃ¢ÂÂdengue, live-attenuated, tetravalent dengue vaccine (CYD-TDV) that is currently approved for use in several countries. In clinical trials, CYD-TDV was efficacious at reducing laboratory-confirmed cases of dengue disease. Efficacy varied by dengue virus (DENV) serotype and prevaccination dengue immune status. We compared the properties of antibodies in naive and DENV-exposed individuals who received CYD-TDV. We depleted specific populations of DENV-reactive antibodies from immune serum samples to estimate the contribution of serotype-cross-reactive and type-specific antibodies to neutralization. Subjects with no preexisting immunity to DENV developed neutralizing antibodies to all 4 serotypes of DENV. Further analysis demonstrated that DENV4 was mainly neutralized by type-specific antibodies whereas DENV1, DENV2, and DENV3 were mainly neutralized by serotype cross-reactive antibodies. When subjects with preexisting immunity to DENV were vaccinated, they developed higher levels of neutralizing antibodies than naive subjects who were vaccinated. In preimmune subjects, CYD-TDV boosted cross-reactive neutralizing antibodies while maintaining type-specific neutralizing antibodies acquired before vaccination. Our results demonstrate that the quality of neutralizing antibodies induced by CYD-TDV varies depending on DENV serotype and previous immune status. We discuss the implications of these results for understanding vaccine efficacy.
Ultraviolet behavior of 6D supersymmetric Yang-Mills theories and harmonic superspace
Creators: name: Bossard, Guillaume
name: Ivanov, Evgeny
name: Smilga, Andrei
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We revisit the issue of higher-dimensional counterterms for the N=(1,1) supersymmetric Yang-Mills (SYM) theory in six dimensions using the off-shell N=(1,0) and on-shell N=(1,1) harmonic superspace approaches. The second approach is developed in full generality and used to solve, for the first time, the N=(1,1) SYM constraints in terms of N=(1,0) superfields. This provides a convenient tool to write explicit expressions for the candidate counterterms and other N=(1,1) invariants and may be conducive to proving non-renormalization theorems needed to explain the absence of certain logarithmic divergences in higher-loop contributions to scattering amplitudes in N=(1,1) SYM.
description: 55 pages, some signs in sections 3 and 4 are corrected without affecting further conclusions
Saperi buoni e utili: il punto di vista degli insegnanti in formazione
Creators: name: Parigi, Laura
name: Di Stasio, Margherita
Publisher: name: Form@re - Open Journal per la formazione in rete
Year: 2015

description: Partendo dal punto di vista di chi opera nella formazione, il presente contributo si propone di approfondire i giudizi degli insegnati con il fine di individuare i saperi che la comunità professionale considera rilevanti. A tal fine si sono analizzati gli esiti dell’indagine TALIS e i monitoraggi di alcuni corsi Indire, reputati rappresentativi per l’ampiezza della popolazione raggiunta. Se TALIS mette in evidenza come in presenza di buoni livelli di partecipazione e soddisfazione persista una percentuale significativa di insegnanti che considerano la proposta di formazione inadeguata, i monitoraggi Indire fanno emergere una richiesta di focalizzazione sui saperi d’esperienza ed evidenziano l’importanza di figure della comunità professionale (insegnanti, esperti disciplinari) che si fanno carico di mediare i saperi per insegnare in buone pratiche. Il confronto tra le fonti non produce esiti che hanno valore di generalizzazione, ma è proposto per mostrare come un’analisi di casi di formazione possa contribuire ad approfondire le tendenze emergenti nelle indagini internazionali.
description: Form@re - Open Journal per la formazione in rete, Vol. 15 No. 3 (2015): Ricerca didattica: fare il punto
Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus
Creators: name: Baric, Ralph S.
name: Madden Jr., Joseph C.
name: Tang, Hsin-Yao
name: Di, Han
name: Brinton, Margo A.
name: Morantz, Esther K.
name: Graham, Rachel L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Members of the order Nidovirales express their structural protein ORFs from a nested set of 3′ subgenomic mRNAs (sg mRNAs), and for most of these ORFs, a single genomic transcription regulatory sequence (TRS) was identified. Nine TRSs were previously reported for the arterivirus Simian hemorrhagic fever virus (SHFV). In the present study, which was facilitated by next-generation sequencing, 96 SHFV body TRSs were identified that were functional in both infected MA104 cells and macaque macrophages. The abundance of sg mRNAs produced from individual TRSs was consistent over time in the two different cell types. Most of the TRSs are located in the genomic 3′ region, but some are in the 5′ ORF1a/1b region and provide alternative sources of nonstructural proteins. Multiple functional TRSs were identified for the majority of the SHFV 3′ ORFs, and four previously identified TRSs were found not to be the predominant ones used. A third of the TRSs generated sg mRNAs with variant leader–body junction sequences. Sg mRNAs encoding E′, GP2, or ORF5a as their 5′ ORF as well as sg mRNAs encoding six previously unreported alternative frame ORFs or 14 previously unreported C-terminal ORFs of known proteins were also identified. Mutation of the start codon of two C-terminal ORFs in an infectious clone reduced virus yield. Mass spectrometry detected one previously unreported protein and suggested translation of some of the C-terminal ORFs. The results reveal the complexity of the transcriptional regulatory mechanism and expanded coding capacity for SHFV, which may also be characteristic of other nidoviruses.
How Self-Evaluation can make schools more effective
Creators: name: Capperucci, Davide
Publisher: name: Form@re - Open Journal per la formazione in rete
Year: 2015

description: Recent European and North American government policies, implementing new systems of evaluation and accountability, have highlighted the use of performance data to inform judgments about schools and stimulate school improvement. This has led to the implementation of school self-evaluation considered as an effective means to increase school quality and effectiveness. Decentralization of education systems has promoted a broadening of educational evaluation methodologies and a conceptualization of theoretical approaches and research about school effectiveness and improvement. This study presents a self-evaluation model, called the ISSEMod, thought to improve school accountability, combining central control managed by public authorities (external control) and the autonomy reserved for schools related to pedagogical, instructional and organizational practices (internal control). Using a sample of 58 Tuscan schools, an empirical and explorative model of school self-evaluation focused on a flexible system of areas and indicators to investigate and analyse school quality, is proposed here.
description: Form@re - Open Journal per la formazione in rete, Vol. 15 No. 3 (2015): Ricerca didattica: fare il punto
Per una Didattica come Scienza dell’Istruzione
Creators: name: Calvani, Antonio
Publisher: name: Form@re - Open Journal per la formazione in rete
Year: 2015

description: In questo lavoro intendo evidenziare come i significativi cambiamenti sopraggiunti negli ultimi decenni negli ambiti dell’Evidence Based Education (EBE) e dell’Instructional Design consentano a quel dominio conosciuto nel nostro Paese come “Didattica” di presentarsi ormai con i caratteri propri di un ambito scientifico. Conseguentemente si impongono nuove scelte e assunzioni di responsabilità circa l’impiego di criteri più rigorosi per valutare ed avvalersi di conoscenze affidabili. Anche i rapporti tra università e scuola, ricerca scientifica e pratica didattica possono risultarne riconfigurati secondo modalità che consentono un maggiore impatto. Al lavoro si aggiunge una breve riflessione sul significato di Evidence Based Education.
description: Form@re - Open Journal per la formazione in rete, Vol. 15 No. 3 (2015): Ricerca didattica: fare il punto
Resolution of diarrhea in an immunocompromised patient with chronic norovirus gastroenteritis correlates with constitution of specific antibody blockade titer
Creators: name: Marty, Francisco
name: Baric, Ralph S.
name: Yount, Boyd L.
name: Knoll, Bettina M.
name: Lindesmith, Lisa C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Norovirus gastroenteritis in immunocompromised hosts can result in a serious and prolonged diarrheal illness. We present a case of chronic norovirus disease during rituximab-bendamustine chemotherapy for non-Hodgkin's lymphoma. We show for the first time a correlation between norovirus strain-specific antibody blockade titers and symptom improvement in an immunocompromised host.
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro
Creators: name: Peel, Sheila A.
name: Bright, Patricia
name: Baric, Ralph S.
name: Yount, Boyd
name: Handy, Jean
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Stepwise selection for increased mefloquine resistance in a line of Plasmodium falciparum in vitro resulted in increased resistance to halofantrine and quinine, increased sensitivity to chloroquine, and amplification and overexpression of the P-glycoprotein gene homolog (pfmdr1). A point mutation (tyrosine to phenylalanine) noted at amino acid 86 in pfmdr1 in the mefloquine-resistant line W2mef was amplified in more resistant lines derived from it by in vitro selection pressure with mefloquine. Conversely, lines selected for increased chloroquine resistance exhibited a revertant phenotype that was sensitive to mefloquine and halofantrine. These lines also demonstrated increased sensitivity to quinine, loss of amplification of pfmdr1, loss of the mefloquine/halofantrine phenylalanine-86 mutation, and selection for a tyrosine-86 mutation previously associated with chloroquine resistance. These findings provide strong evidence for pfmdr1 mediating cross-resistance to halofantrine and mefloquine in P. falciparum in vitro.
Statistical analysis of the temporal single-photon response of superconducting nanowire single photon detection
Creators: name: He, Y. -H.
name: Chao-Lin, L.
name: Zhang, W. -J.
name: Zhang, L.
name: Wu, J. -J.
name: Chen, S. -J.
name: You, L. -X.
name: Wang, Z.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Counting rate is a key parameter of superconducting nanowire single photon detectors (SNSPD) and is determined by the current recovery time of an SNSPD after a detection event. We propose a new method to study the transient detection efficiency (DE) and pulse amplitude during the current recovery process by statistically analyzing the single photon response of an SNSPD under photon illumination with a high repetition rate. The transient DE results match well with the DEs deduced from the static current dependence of DE combined with the waveform of a single-photon detection event. This proves that the static measurement results can be used to analyze the transient current recovery process after a detection event. The results are relevant for understanding the current recovery process of SNSPDs after a detection event and for determining the counting rate of SNSPDs.
description: 11 pages,4 figures
Poisson reduction as a coisotropic intersection
Creators: name: Safronov, Pavel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: Mathematical Physics (math-ph)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We give a definition of coisotropic morphisms of shifted Poisson (i.e. $P_n$) algebras which is a derived version of the classical notion of coisotropic submanifolds. Using this we prove that an intersection of coisotropic morphisms of shifted Poisson algebras carries a Poisson structure of shift one less. Using an interpretation of Hamiltonian spaces as coisotropic morphisms we show that the classical BRST complex computing derived Poisson reduction coincides with the complex computing coisotropic intersection. Moreover, this picture admits a quantum version using brace algebras and their modules: the quantum BRST complex is quasi-isomorphic to the complex computing tensor product of brace modules.
description: 35 pages
Information search in times of crisis: How Google trends can inform policy makers
Creators: name: Rotter, Dominik
name: Doebler, Philipp
name: Schmitz, Florian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: COVID-19
subject: Infodemiology
subject: Infosurveillance
subject: Pandemic
subject: SARS-CoV-2 virus

description: In the face of the COVID-19 pandemic, the German government and the sixteen German federal states issued a variety of counter measures to decelerate the spread of the SARS-CoV-2 virus to prevent a collapse of the healthcare infrastructure. These measures comprised amongst others social distancing, the temporary closure of shops and schools, a ban of large public gatherings and meetings with others not living in the same household. It is fair to assume, that all measures, heavily affected social life and psychological functioning (Goldman, 2020; Steinmetz, Batzdorfer, & Bosnjak, 2020). As Google Trend data can be perceived as a proxy for psychological states and behaviours (Goldman, 2020), we intend to study the effects of countermeasures in conjunction with infection rates and the state of the national economy on people´s search interests during the pandemic. Changes in search interests and their relevant predictors can then be used in order to inform policy makers to adopt their intervention strategies allowing for supporting subpopulations at high risk (Knipe, Evans, Marchant, Gunnell, & John, 2020).
Goal Representation - Replication (mTurk2)
Creators: name: Cheung, Bernice
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: This is the second replication of the Goal Representation using mTurk samples. The goal of the present study is to replicate the 4-factor solution yield from the first mTurk replication study and to explore the individual-level relationship between the latent factors of goal representation and other psychological and cognitive individual differences.
Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro
Creators: name: Peel, Sheila A.
name: Merritt, Stephen C.
name: Handy, Jean
name: Baric, Ralph S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Serial passage of a multidrug-resistant clone of Plasmodium falciparum in concentrations of mefloquine hydrochloride ranging from 30 to 2,400 ng/ml resulted in the derivation of increasingly resistant parasite lines in vitro. Parasite lines isolated in mefloquine concentrations greater than 300 ng/ml demonstrated increased vacuolization, enhanced pigment production, and increased growth rates as compared with the progenitor clone, W2-mef. Although microdilution incorporation assays demonstrated that the 50% inhibitory concentration (IC50) of mefloquine were similar for all lines, the IC90, IC95, and IC99 levels were significantly increased. Growth rate assays performed in 5% hematocrit suspensions demonstrated different levels of mefloquine resistance among these lines. Under these conditions the most resistant line, Mef 2.4, grew efficiently in approximately 10-fold higher concentrations of mefloquine than the progenitor clone W2-mef. Analysis of drug susceptibility profiles to mefloquine hydrochloride, chloroquine diphosphate, quinine sulfate, and halofantrine hydrochloride indicated that selection for high levels of mefloquine resistance had resulted in significant increases in resistance to halofantrine and increased sensitivity to chloroquine. The phenotypic changes demonstrated in the most resistant line, Mef 2.4, reflect a multidrug resistant-like phenotype, and appear to mimic changes recently reported in drug susceptibility profiles of recrudescent isolates following mefloquine treatment failures in Thailand.
Exploring the experience of receiving a diagnosis of autism in adulthood: A systematic review protocol
Creators: name: Nayyar, Juwayriyah
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Adulthood
subject: Autism
subject: Autism Spectrum Condition
subject: Diagnosis

description: A protocol for a systematic review of research exploring the experience of receiving a diagnosis of autism in adulthood
A remark on norm inflation with general initial data for the cubic nonlinear Schrödinger equations in negative Sobolev spaces
Creators: name: Oh, Tadahiro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q55

description: In this note, we consider the ill-posedness issue for the cubic nonlinear Schrödinger equation. In particular, we prove norm inflation based at every initial condition in negative Sobolev spaces below or at the scaling critical regularity.
description: 18 pages. Updated references
MACROECONOMIC EFFECTS OF FOREIGN AID IN ETHIOPIA USING DYNAMIC COMPUTABLE GENERAL EQUILIBRIUM MODEL
Creators: name: Nguse Khasay
Publisher: name: Zenodo
Year: 2014

description: Macroeconomic effects of foreign aid depend on how it affects savings, investment and government behaviour. The study used recursive dynamic general equilibrium (DCGE), auto regressive distributed lag model approach to cointegration (ARDL) and vivid three gap based descriptive reports aiming to find out the preponderant effect. The data used in descrptive analysis and ARDL were collected from World Bank, Organization for Economic Cooperation and Development, and International Monetary Fund data bases. DCGE requires social accounting matrix (SAM) and that was obtained from Ethiopian Development Research Institute (EDRI). The SAM was built in 2005 and updated its key accounts in 20091 . Using recursive DCGE, the study shows that aid inflow can result in export reduction and exchange rate appreciation. But, it leads to higher gevernemt revenue, expenditure and savings. Aid"s effect in total absorption and gross domestic product is not discernible. Thus, the study"s results are ambiguous to generalize. The long run results of the ARDL model also show significant positive relationship between national income and domestic savings. However, the relationsip between Development Assistance Committee (DAC)-aid inflow and domestic savings is significantly inverse2 .
Funzioni esecutive in interazione con dispositivi di narrazione multilineare per una formazione generativa evidence based
Creators: name: Salmaso, Luisa
Publisher: name: Form@re - Open Journal per la formazione in rete
Year: 2015

description: La promozione degli apprendimenti in partecipazione e cooperazione con gli altri, la pianificazione da concretizzare attraverso azioni organizzate, il far scaturire dal problem setting narrativo un processo dinamico, prospettico e costruttivo, in cui l’alunno viene sostenuto dal formatore e dalla struttura narrativa che guida, sono in grado di sollecitare la scoperta di percorsi possibili, sostenendo il carico cognitivo implicato in processi complessi, quali le funzioni neuropsicologiche di tipo esecutivo (Hughes, 2011; Zoccolotti, 2010). Il modello qui presentato può permettere l’attivazione di processi di apprendimento multiplo, infatti, pur inquadrato nel paradigma socio-culturale costruzionista, implica anche strategie afferenti a modelli istruzionali, cognitivi e metacognitivi dell’apprendimento, offrendo una palestra articolata per uno sviluppo di abilità cognitive e sociali, in una prospettiva formativa generativa evidence based.
description: Form@re - Open Journal per la formazione in rete, Vol. 15 No. 3 (2015): Ricerca didattica: fare il punto
Superconducting nanowire single-photon detectors at a wavelength of 940 nm
Creators: name: Zhang, W. J.
name: Li, H.
name: You, L. X.
name: He, Y. H.
name: Zhang, L.
name: Liu, X. Y.
name: Yang, X. Y.
name: Wu, J. J.
name: Guo, Q.
name: Chen, S. J.
name: Wang, Z.
name: Xie, X. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We develop single-photon detectors comprising single-mode fiber-coupled superconducting nanowires, with high system detection efficiencies at a wavelength of 940 nm. The detector comprises a 6.5-nm-thick, 110-nm-wide NbN nanowire meander fabricated onto a Si substrate with a distributed Bragg reflector for enhancing the optical absorptance. We demonstrate that, via the design of a low filling factor (1/3) and active area (Φ = 10 μm), the system reaches a detection efficiency of ~60% with a dark count rate of 10 Hz, a recovery time <12 ns, and a timing jitter of ~50 ps.
description: 12 pages, 3 figures
Estudio De Caso Sobre Economía Política
Creators: name: Masís, Héctor
Publisher: name: Zenodo
Year: 2025

description: Trabajo Evaluativo: "LO QUE TRAJO LA CRISIS PETROLERA DE 1973". Asignatura: ECONOMÍA POLÍTICA. Estudiante: HÉCTOR MASÍS. Docente: Doctor Mtro. CIRO LABRADA. Universidad: UNINI – MÉXICO.
Salty, neutral buffers provide a way to combine capillary electrophoresis enzyme activity and PCR gene expression assays.
Creators: name: Diiorio, Marisa
name: Peterson, Brae
name: Allbritton, Nancy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Capillary Electrophoresis (CE) is the technique behind many chemical cytometry assays. CE separates compounds in an electric field based off the size and charge or their electrophoretic mobility. Generally, the EO flow pushes positively and negatively charged molecules towards the cathode. By weakening the EO flow, negatively charged nucleic acids could be collected at the anode of the capillary while enzyme activity reporters are detected near the cathode. We show that salty and neutral buffers weaken the EO flow so that DNA and RNA have a net mobility towards the anode. We demonstrate that single cell levels of DNA (5 pg) can be collected at the anode and analyzed using PCR using this CE-Seq method.
Changes of Kondo effect in the junction with DIII-class topological and $s$-wave superconductors
Creators: name: Gao, Zhen
name: Gong, Wei-Jiang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We discuss the change of the Kondo effect in the Josephson junction formed by the indirect coupling between a one-dimensional \emph{DIII}-class topological and s-wave superconductors via a quantum dot. By performing the Schrieffer-Wolff transformation, we find that the single-electron occupation in the quantum dot induces various correlation modes, such as the Kondo and singlet-triplet correlations between the quantum dot and the $s$-wave superconductor and the spin exchange correlation between the dot and Majorana doublet. Moreover, it plays a nontrivial role in modifying the Josephson effect, leading to the occurrence of anisotropic and high-order Kondo correlation. In addition, due to the quantum dot in the Kondo regime, extra spin exchange correlations contribute to the Josephson effect as well. Nevertheless, if the \emph{DIII}-class topological superconductor degenerates into \emph{D}-class because of the destruction of time-reversal invariance, all such terms will disappear completely. We believe that this work shows the fundamental difference between the \emph{D}- and \emph{DIII}-class topological superconductors.
description: 10 pages, 3 figures. Any comment is welcome
BEER analysis of Kepler and CoRoT light curves: IV. Discovery of four new low-mass white dwarf companions in the Kepler data
Creators: name: Faigler, Simchon
name: Kull, Ilya
name: Mazeh, Tsevi
name: Kiefer, Flavien
name: Latham, David W.
name: Bloemen, Steven
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We report the discovery of four short-period eclipsing systems in the Kepler light curves, consisting of an A-star primary and a low-mass white dwarf (WD) secondary (dA+WD) - KIC 4169521, KOI-3818, KIC 2851474, and KIC 9285587. The systems show BEaming, Ellipsoidal and Reflection (BEER) phase modulations together with primary and secondary eclipses. These add to the 6 Kepler and 18 WASP short-period eclipsing dA+WD binaries that were previously known. The light curves, together with follow-up spectroscopic observations, allow us to derive the masses, radii, and effective temperatures of the two components of the four systems. The orbital periods, of 1.17-3.82 days, and WD masses, of 0.19-0.22 Msun, are similar to those of the previously known systems. The WD radii of KOI-3818, KIC 2851474, and KIC 9285587 are 0.026, 0.035, and 0.026 Rsun, respectively, the smallest WD radii derived so far for short-period eclipsing dA+WD binaries. These three binaries extend the previously known population to older systems with cooler and smaller WD secondaries. KOI-3818 displays evidence for a fast-rotating primary and a minute but significant eccentricity of ~0.0015. These features are probably the outcome of the mass-transfer process.
description: 23 pages, 7 figures and 4 tables. Accepted by The Astrophysical Journal
Exercising or gaming? Exergaming!!
Creators: name: Marasso, Danilo
Publisher: name: Form@re - Open Journal per la formazione in rete
Year: 2015

description: L’utilità dei videogiochi come strumenti per la didattica è un argomento controverso, in particolare per quando riguarda l’insegnamento dell’educazione fisica. L’obiettivo di questo intervento è proporre una revisione della letteratura che consenta di approfondire il dibattito sull’argomento, tramite l’analisi delle potenzialità e delle problematiche legate all’utilizzo dei videogiochi appartenenti alla categoria degli exergames. Gli aspetti considerati riguardano l’influenza degli exergames sui domini dell’apprendimento, con particolare attenzione agli aspetti legati al movimento e alla motivazione. Infine verranno presentati alcuni esempi di come è possibile integrare gli exergames all’interno delle lezioni di educazione fisica.
description: Form@re - Open Journal per la formazione in rete, Vol. 15 No. 3 (2015): Ricerca didattica: fare il punto
Selective Application of Gender Norms? Wartime Sexual Violence and Responses to Civil Conflict
Creators: name: Kreft, Anne-Kathrin
name: agerberg, mattias
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: This study is a follow-up experiment that is included in the project “Selective Application of Gender Norms? Wartime Sexual Violence and Responses to Civil Conflict.” The project was originally registered on EGAP on 2017-10-27 and is now stored on the OSF server (https://osf.io/jce3q/). The original pre-analysis plan is titled 20171027AA_PAP.
Study 1: Moral exemplars
Creators: name: Baumert, Anna
name: Sckopke (Halmburger), Anna
name: Sasse, Julia
name: Toribio-Flórez, Daniel
name: Wagner, Jenny
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: awards
subject: moral
subject: moral courage
subject: personality dispositions

description: This folder contains important information on Study 1 of the "Moral courage" project
Current Status of Genitourinary Cancer Survivorship in the United States; Review of the Literature and Analysis of the Health Care Cost and Utilization Project Database (HCUP)
Creators: name: Peterson, Andrew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Introduction: Improved care for patients with cancer is leading to an exponential growth in cancer survivors that may number over 20 million by 2024. I utilized data from the HealthCare Cost and Utilization Project (HCUP) along with a review of the contemporary literature to establish an understanding of the needs of cancer survivors in the United States.Methods:  After performing a Medline search to identify the needs of cancer survivors and relevant side effects, I utilized the National (Nationwide) Inpatient Sample (NIS) and Nationwide Emergency Department Sample (NEDS) to identify trends for radiation cystitis, radiation bowel problems and fistula disease.  Descriptive statistics are presented including initial rates per 100,000 of visits and discharges, hospital charges, costs, and ranges as well as standard deviation. I performed a regression analysis to assess linearity of the trends in the rates of visits to the emergency room (NEDS) and discharges from hospitals (NIS). I used Z statistical tests to assess the statistical significance of changes in interval scale data such as costs and charges for first year measurements compared to most recent measurements in HCUP.  All analyses were weighted using NIS and NEDS weights and covariance matrices. P-values were computed using an alpha of 0.05 and 95% confidence intervals as criteria for statistical significance. Results: The literature review produced 86 scientific articles for review. NED and NIS show that emergency room visits (P=0.0009) and discharges (P=<0.0001) for radiation cystitis (ICD-9 595.82, irradiation cystitis) per 100,000 increased from 1997 to 2014. The relative discharge proportion of men vs. women changed over this time period as well with men accounting for 66.8% of all discharges for radiation cystitis in 2006 and 81.7% of all discharges in 2015 (P<0.0001) and their average age increased significantly from 74.6 years (standard error 0.55) in 1997 to 77.0 years (standard error 0.46) in 2015 (P = 0.0014).Conclusion: With 16.9 million people, cancer survivors currently number more than twice the size of New York City and the number with side effects is increasing significantly. Literature review indicates that there are many opportunities to improve the care of this growing population. Recommendations for future research and policy development to increase resources for this population are suggested.
Performance Analysis and Prediction in Educational Data Mining: A Research Travelogue
Creators: name: Thakar, Pooja
name: Mehta, Anil
name: Manisha
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: In this era of computerization, education has also revamped itself and is not limited to old lecture method. The regular quest is on to find out new ways to make it more effective and efficient for students. Nowadays, lots of data is collected in educational databases, but it remains unutilized. In order to get required benefits from such a big data, powerful tools are required. Data mining is an emerging powerful tool for analysis and prediction. It is successfully applied in the area of fraud detection, advertising, marketing, loan assessment and prediction. But, it is in nascent stage in the field of education. Considerable amount of work is done in this direction, but still there are many untouched areas. Moreover, there is no unified approach among these researches. This paper presents a comprehensive survey, a travelogue (2002-2014) towards educational data mining and its scope in future.
description: 9 pages
Imparare a imparare attraverso il museo scolastico: tracce di nuove potenzialità di uno strumento didattico tardo-ottocentesco
Creators: name: Pizzigoni, Francesca Davida
Publisher: name: Form@re - Open Journal per la formazione in rete
Year: 2015

description: L’articolo mira ad approfondire una specifica pratica didattica, assai diffusa in Italia e all’estero tra la seconda metà dell’Ottocento e la prima metà del Novecento: il museo scolastico. Frutto del positivismo e del pensiero pedagogico legato all’attivismo, esso era una collezione presente in particolare presso le scuole primarie e si presentava come insieme di oggetti (naturali e artificiali) che circondavano la vita quotidiana dell’alunno e che venivano utilizzati di volta in volta a seconda della lezione trattata, al fine di creare legami solidi tra apprendimento e ambiente e tra apprendimento e contesto sociale. Dopo aver affrontato la storia di tale pratica didattica, l’articolo intende mostrare aspetti di attualità del museo scolastico e valutare l’opportunità di consideralo oggi come strumento capace di agevolare l’alunno nell’imparare a imparare.
description: Form@re - Open Journal per la formazione in rete, Vol. 15 No. 3 (2015): Ricerca didattica: fare il punto