cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Impact of fishmeal replacement with poultry meal on rainbow trout (Oncorhynchus mykiss) nutrition, physiology and performance
Creators: name: Latif, K
Publisher: name: University Of Tasmania
Year: 2023

description: The future sustainability of aquaculture will depend in part on the reduction of fishmeal (FM) used in fish feeds and the development of economically alternative protein sources. Poultry meal (PM) is one example of an alternative protein source. The aim of this study was to understand the effects of FM replacement with PM on nutrition, physiology and performance of rainbow trout. Four independent experiments using isoenergetic and isonitrogenous feeds (22 MJ GE `kg^-1` DM, 400 g `kg^-1` DM of crude protein) were carried out. An initial study investigated the effect of replacing FM protein with increasing amounts of PM protein in which 0, 20, 30 and 40% FM protein was replaced with PM protein. Fish were grown in freshwater at 15¬¨‚àûC for 84 days, during which time they were fed twice daily at 2% bw `d^-1`.The results indicated that PM protein can be used to replace up to 40% of the FM protein without impaired fish growth, apparent digestibility of crude protein, insulin like growth factor I (IGF I) and cortisol. A further study was carried out to determine the effects of replacement on apparent digestibility where twelve isoenergetic and isonitrogenous feeds were formulated in which 0, 10, 20, 30, 40, 50, 60, 70, 80, 90, 95 and 100% FM protein was replaced with PM protein. Fish were grown in freshwater at 15¬¨‚àûC for 27 days, during which time they were fed twice daily until satiation. Faeces were stripped from fish on day 3, 9 and day 27. Effects of poultry meal inclusion level on apparent digestibility showed the significant negative linear relationships between PM inclusion and apparent digestibility measured as AD crude protein, AD total lipid and AD gross energy. There were no significant differences in AD crude protein or AD total lipid between the three adaptation times. However, AD gross energy increased over time. A further experiment evaluated the effects of temperature on FM with increasing PM at two different temperatures (15¬¨‚àûC and 20¬¨‚àûC). Twelve isoenergetic and isonitrogenous feeds were formulated in which 0, 10, 20, 30, 40, 50, 60, 70, 80, 90, 95 and 100% FM protein was replaced with PM protein. Fish were fed twice daily at 2% bw `d^-1` for a period of 112 days. Results indicate the high potential of PM as an alternative protein source at optimal and high temperatures. In addition, result on histology of the distal intestine showed that increase in the number of goblet cells (GC) and decrease in the width of supranuclear vacuoles (SNV) in fish fed diets containing greater than 90% of PM protein at both temperatures. The last experiment was designed to test the effects of supplementary essential amino acids (L-lysine and L-histidine) on rainbow trout. Fish was fed either a set daily ration of 1.7% bw¬¨‚àë`d^-1` or fed to satiation. The results indicated that supplementary essential amino acids (EAA), L-lysine and Lhistidine in PM diet did not improve growth of rainbow trout.
Projected Crop Market and Tennessee Farm Income Impacts From the COVID-19 Pandemic
Creators: name: Smith, S. Aaron
name: English, Burton C.
name: Menard, R. Jamey
name: Hughes, David W.
name: Jensen, Kimberly L.
name: Smith, S. Aaron
name: English, Burton C.
name: Menard, R. Jamey
name: Hughes, David W.
name: Jensen, Kimberly L.
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Crop Production/Industries
subject: Demand and Price Analysis
subject: COVID-19
subject: producer
subject: income
subject: corn
subject: soybean
subject: cotton
subject: price

description: The COVID-19 pandemic has affected all aspects of agricultural commodity production and distribution. Substantial price declines have been experienced for Tennessee row crops, specialty crops, livestock and dairy producers. The 2019 crop’s price declines in Tennessee for corn, soybean, cotton and wheat from January 2 to the end of each crop’s 2019/20 marketing year are analyzed in this paper. Additionally, estimates of the federal aid issued to producers through Coronavirus Food Assistance Program (CFAP) direct payments are provided.
Is There Any Modern and Efficient Cure of nCOVID-19?
Creators: name: Alhiti, Hazim
Publisher: name: figshare
Year: 2021
Subjects: subject: 110804 Medical Virology
subject: FOS: Health sciences

description: Introduction:  COVID-19 virus produces a viral infection disease that hits any person and  advances into threatening ailment and death. Besides, this respiratory outbreak was  identified in 2019 then transported by direct communication in 2020 till now.  Consequently, any person could send this virus despite the mild flu he suffered and  recovered without particular medication. Moreover, COVID communicability might  proceed to a critical state in distinct patients who had therapeutic ailments as  immunocompromised patients, asthmatics, and diabetic patients [1].  The well-known practice in simple sufferers began at home. Accordingly, the  doctors' advice constitutes bed rest, good hydration, vitamins supplements, oral medication  to alleviate aches plus lessen fever. Furthermore, the sufferer followed the official health  regulations and took the drugs in recorded applications. The treatment of medium-difficult  patients of nCOVID-19 necessitates hospital entry and an advanced drug regimen. Thus, a  professional doctor-on-call orders drug regimens: Tocilizumab, Dexamethasone,  Anticoagulation drugs, Baricitinib +/- remdesivir, monoclonal antibodies, patient’s plasma,  hydroxychloroquine, oxygen supply, and NSAID. Moreover, nCOVID-19 could cause death despite these recorded meditations [2].  Argument:  The respiratory experts are in doubt of the effectiveness of the bacteriophage and  nanoparticles on nCOVID-19 disease.
Nonequilibrium dynamics of weakly and strongly paired superconductors
Creators: name: Gurarie, V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study small oscillations of the order parameter in weakly and strongly paired superconductors driven slightly out of equilibrium, in the collisionless approximation. While it was known for quite some time that the amplitude of the oscillations in a weakly paired superconductor decays as 1/t^(1/2), we show that in a superconductor sufficiently strongly paired so that its fermions form bound states usually referred to as molecules, these oscillations decay as 1/t^(3/2). The transition between these two regimes happens when the chemical potential of the superconductor vanishes, thus the behavior of the oscillations can be used to distinguish weakly and strongly paired superconductors. These results are obtained in the mean field approximation which may not be reliable in the crossover region between the strong and weak pairing, so we also obtain identical results within the two-channel model, which can be tuned to be reliable throughout the entire crossover, although it then describes a special type of interactions between the fermions which may be difficult to observe experimentally. Finally, we interpret the result in the strongly paired superconductor as the probability of the molecular decay as a function of time.
Target and beam-target spin asymmetries in exclusive π+ and π- Electroproduction with 1.6- to 5.7-GeV electrons
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: nucl-ex

description: © 2016 American Physical Society. Beam-target double-spin asymmetries and target single-spin asymmetries in exclusive π+ and quasiexclusive π- electroproduction were obtained from scattering of 1.6- to 5.7-GeV longitudinally polarized electrons from longitudinally polarized protons (for π+) and deuterons (for π-) using the CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab. The kinematic range covered is 1.11.5 GeV. Very large target-spin asymmetries are observed for W>1.6 GeV. When combined with cross-section measurements, the present results can provide powerful constraints on nucleon resonance amplitudes at moderate and large values of Q2, for resonances with masses as high as 2.3 GeV.
Iodidobis(≠5-penta-methyl-cyclo-penta-dien-yl)titanium(III)
Creators: name: Kessler, M.
name: Spannenberg, A.
name: Rosenthal, U.
Publisher: name: Chester : International Union of Crystallography
Year: 2010
Subjects: subject: Crystal structure
subject: Chemistry
subject: Crystallography
subject: 540

description: In the title complex mol-ecule, [Ti(C10H15) 2I], the paramagnetic Ti(III) atom is coordinated by two penta-methyl-cyclo-penta-dienyl (Cp*) ligands and one iodide ligand. The two Cp*ligands are in a staggered orientation. The coordination geometry at the titanium atom can be described as distorted trigonal-planar.
Constraining new physics with B to K* mu+ mu- in the early LHC era
Creators: name: Bharucha, Aoife
name: Reece, William
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We investigate the observables available in the angular distribution of B to K* mu+ mu- to identify those suitable for measurements in the first few years of LHC data taking. As experimental uncertainties will dominate, we focus on observables that are simple to measure, while maximizing the potential for discovery. There are three observables that may be extracted by counting signal events as a function of one or two decay angles and correspond to large features of the full angular distribution in the Standard Model: Afb, Fl, and S5. Two of these are well known in the experimental community; however, we show that measuring S5 adds complementary sensitivity to physics beyond the Standard model. Like Afb, it features a zero-crossing point with reduced hadronic uncertainties at leading order and in the large recoil limit. We explore the experimental sensitivity to this point at LHCb and show that it may be measured with high precision due to the steepness of the S5 distribution. Current experimental model independent constraints on parameter space are presented and predictions made for the values of the Afb and S5 zero-crossing points. The relative impact of LHCb measurements of Afb, Fl, and S5, with 2 fb^(-1) of integrated luminosity, is assessed. These issues are explored with a new model of the decay that can be used with standard simulation tools such as EVTGEN.
description: 32 pages, 9 figures, 9 tables. v2: Figure caption corrected and 2 references added. Version submitted to journal.
Range conditions for a spherical mean transform
Creators: name: Agranovsky, Mark
name: Finch, David
name: Kuchment, Peter
Publisher: name: arXiv
Year: 2009
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 35L05, 92C55, 65R32, 44A12

description: The paper is devoted to the range description of the Radon type transform that averages a function over all spheres centered on a given sphere. Such transforms arise naturally in thermoacoustic tomography, a novel method of medical imaging. Range descriptions have recently been obtained for such transforms, and consisted of smoothness and support conditions, moment conditions, and some additional orthogonality conditions of spectral nature. It has been noticed that in odd dimensions, surprisingly, the moment conditions are superfluous and can be eliminated. It is shown in this text that in fact the same happens in any dimension.
Spontaneous spin current due to triplet superconductor--ferromagnet interfaces
Creators: name: Brydon, P. M. R.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We examine the appearance of a spontaneous bulk spin current in a triplet superconductor in contact with a metallic ferromagnet. The spin current results from the spin-flip of Cooper pairs upon reflection from the interface with the ferromagnet, and is shown to display strong similarities to the spontaneous charge current in a Josephson junction. We express the spin current in terms of the Andreev reflection coefficients, which are derived by the construction of the quasiclassical scattering wavefunctions. The dependence of the spin current upon a number of parameters is investigated, in particular the orientation of the magnetic moment of the ferromagnet, the exchange splitting, the temperature, and the orbital pairing state of the triplet superconductor.
description: 8 pages, 7 figures, RevTeX; revised version with corrected text and figure 5(c), added references
Parton fragmentation functions
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: High-energy collisions
Parton fragmentation
Spin physics

description: © 2016 Elsevier B.V. The field of fragmentation functions of light quarks and gluons is reviewed. In addition to integrated fragmentation functions, attention is paid to the dependence of fragmentation functions on transverse momenta and on polarization degrees of freedom. Higher-twist and di-hadron fragmentation functions are considered as well. Moreover, the review covers both theoretical and experimental developments in hadron production in electron–positron annihilation, deep-inelastic lepton–nucleon scattering, and proton–proton collisions.
Revisiting the fossil group candidates UGC 842 and NGC 6034
Creators: name: de Oliveira, Raimundo Lopes
name: Carrasco, Eleazar Rodrigo
name: de Oliveira, Claudia Mendes
name: Bortoletto, Daiana Ribeiro
name: Cypriano, Eduardo
name: Sodré, Laerte
name: Neto, Gastão Bierrenbach Lima
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a new insight on NGC 6034 and UGC 842, two groups of galaxies previously reported in the literature as being fossil groups. The study is based on optical photometry and spectroscopy obtained with the CTIO Blanco telescope and Sloan Digital Sky Survey archival data. We find that NGC 6034 is embedded in a large structure, dominated by three rich clusters and other small groups. Its first and next four ranked galaxies have magnitude differences in the r band and projected distances which violate the optical criteria to classify it as a fossil group. We confirm that the UGC 842 group is a fossil group, but with about half the velocity dispersion that is reported in previous works. The velocity distribution of its galaxies reveals the existence of two structures in its line of sight, one with sigmaV ~ 223 km/s and another with sigmaV ~ 235 km/s, with a difference in velocity of ~820 km/s. The main structure is dominated by passive galaxies, while these represent ~60% of the second structure. The X-ray temperature for the intragroup medium of a group with such a velocity dispersion is expected to be kT ~0.5-1 keV, against the observed value of kT ~1.9 keV reported in the literature. This result makes UGC 842 a special case among fossil groups because (1) it represents more likely the interaction between two small groups, which warms the intragroup medium and/or (2) it could constitute evidence that member galaxies lost energy in the process of spiraling toward the group center, and decreased the velocity dispersion of the system. As far as we know, UGC 842 is the first low-mass fossil group studied in detail.
description: 18 pages, 8 figures, published in AJ
D7.1.1 – Market Research and Strategy Report
Creators: name: Fotakidis, Dimitris
name: Manouselis, Nikos
name: Kouriantaki Eirini
name: Alina, Petri
name: Mpokogiani Ifigeneia
Publisher: name: Zenodo
Year: 2020
Subjects: food safety
big data
standards
certification

description: This document is the first version of the Market Research and Strategy Report (D7.1 due in M6)
 for the Food Safety Market Project (TheFSM), an Innovation Action supported by the Horizon 2020
 programme of the European Commission (Grant agreement ID: 871703). General information on
 the project, including its objectives and partners, facts and results, can be found on
 foodsafetymarket.eu.
 The document offers a preliminary market assessment report, starting with the identification of
 stakeholders in a broader context, and an analysis of the competitive Food Safety landscape.
 Second, value propositions for key customer segments have been identified, along with
 opportunities and challenges for market entry and growth. A methodology for risk analysis for
 the TheFSM adoption has been developed. Together, these pieces lay out the groundwork for
 business planning and business growth in the subsequent stages of the project.
 This deliverable builds on the critical findings from the D1.1 Report on Requirements for TheFSM.
 It is conceived as a living document that will be continually enriched with new insights and
 perspectives. The Report is centered around the following underlying objectives:
 • Formulate a business model and a growth strategy, supported by risk assessment and
 practical advice for the adoption of the TheFSM in key customer segments;
 • Deliver the exploitation strategy, for the benefit of the partners and the European Food
 Safety industry, while protecting intellectual property created by the project.
 Further work on the market analysis will be carried out in M12 of the TheFSM project, as part of
 the deliverable D7.2 Ongoing Documentation of Governance and Business Models. In M12, we
 will publish our Annual Report of Marketing, Sales & Partnership Activities (D7.3), whereas in M36
 we will release D7.4 Future Sustainability Roadmap for TheFSM.
Particulate matter emissions from biochar-amended soils as a potential tradeoff to the negative emission potential
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: 0503 Soil Sciences

description: © 2016 The Author(s). Novel carbon sequestration strategies such as large-scale land application of biochar may provide sustainable pathways to increase the terrestrial storage of carbon. Biochar has a long residence time in the soil and hence comprehensive studies are urgently needed to quantify the environmental impacts of large-scale biochar application. In particular, black carbon emissions from soils amended with biochar may counteract the negative emission potential due to the impacts on air quality, climate, and biogeochemical cycles. We investigated, using wind tunnel experiments, the particulate matter emission potential of a sand and two agriculturally important soils amended with different concentrations of biochar, in comparison to control soils. Our results indicate that biochar application considerably increases particulate emissions possibly by two mechanisms-the accelerated emission of fine biochar particles and the generation and emission of fine biochar particles resulting from abrasion of large biochar particles by sand grains. Our study highlights the importance of considering the background soil properties (e.g., texture) and geomorphological processes (e.g., aeolian transport) for biochar-based carbon sequestration programs.
Interrelationships of child appetite, weight and snacking among Hispanic preschoolers
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2018
Subjects: Appetite
child
snacking
weight

description: © 2016 The Authors. Pediatric Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation. Background: Snacking among US preschoolers has increased in recent decades, raising questions about whether snacking contributes to dietary excess. Objectives: This research aimed to characterize snacking contributions to dietary excess and to evaluate associations with appetite and weight among preschool-aged children. Methods: This study is a cross-sectional, observational study of 187 Hispanic low-income preschoolers. Three 24-h dietary recalls were used to assess snacking frequency and parameters of dietary excess including energy, saturated fat, trans fats and added sugars. Parental reports of child satiety responsiveness, food responsiveness, and enjoyment of food were obtained. Child height and weight were measured. Results: Children consumed 28% (395 kcal) of daily energy from snacks eaten at 2.3 ± 1.0 occasions per day. Greater snacking frequency was associated with greater daily intakes of energy (p < 0.05) and added sugars (p < 0.001). Among overweight/obese children, higher enjoyment of food was associated with more frequent snacking and greater energy intake from snacks (p = 0.01). Inverse associations of enjoyment of food with snacking frequency and energy intake were seen among normal weight children (p < 0.05). Conclusions: More frequent snacking among low-income Hispanic preschoolers may contribute to excessive intakes of energy and added sugars, particularly among overweight/obese children with greater motivation to eat.
Measurement of collective excitations in VO2 by resonant inelastic x-ray scattering
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: cond-mat.str-el

description: © 2016 American Physical Society. Vanadium dioxide is of broad interest as a spin-12 electron system that realizes a metal-insulator transition near room temperature, due to a combination of strongly correlated and itinerant electron physics. Here, resonant inelastic x-ray scattering is used to measure the excitation spectrum of charge and spin degrees of freedom at the vanadium L edge under different polarization and temperature conditions, revealing excitations that differ greatly from those seen in optical measurements. These spectra encode the evolution of short-range energetics across the metal-insulator transition, including the low-temperature appearance of a strong candidate for the singlet-triplet excitation of a vanadium dimer.
title: Wskaźniki, parametry i modele w kształtowaniu intensywnej wielorodzinnej zabudowy mieszkaniowej
title: Indicators, parameters and models in shaping compact multi-family residental development
Creators: name: Bradecki, Tomasz
Publisher: name: Wydawnictwo Politechniki Śląskiej
Year: 2021
Subjects: projektowanie urbanistyczne
zespoły mieszkaniowe
ocena ilościowa
zwarta zabudowa
wskaźniki urbanistyczne
zrównoważona zabudowa mieszkaniowa
zabudowa wielorodzinna
intensywna zabudowa mieszkaniowa
środowisko mieszkaniowe
projektowanie architektoniczne
ocena walorów przestrzennych
modele architektoniczne
zabudowa mieszkaniowa

description: W monografii omówiono rolę wskaźników, parametrów oraz modeli w analizie i projektowaniu urbanistycznym zespołów mieszkaniowych. Przeanalizowano znaczenie powyższych dla kształtowania środowiska zabudowy w kontekście aktualnych tendencji, jakie można zaobserwować w projektach i realizacjach zabudowy mieszkaniowej w Polsce. Szczególną uwagę zwrócono na wzajemne relacje między wybranymi wskaźnikami i parametrami. W dysertacji zostało również poruszone zagadnienie kształtowania zabudowy mieszkaniowej w ujęciu ilościowym. Podjęta została dyskusja na temat możliwych wartości brzego-wych wskaźników i parametrów oraz przedstawiono liczne zrealizowane przykłady (w tym ich modele). Część opisanych przypadków to projekty z praktyki zawodowej autora (czynnego zawodowo architekta i urbanisty). Pozostałe przypadki przedstawione w pracy odwołują się do badań zrealizowanych zespołów mieszkaniowych w Polsce. W pracy zaproponowano nowe definicje wybranych wskaźników, a ponadto zaprezentowano przykłady analiz, projektów oraz eksperymentów wykonywanych za pomocą modeli w oprogramowaniu BIM oraz parametrycznym. Coraz powszechniejsze wykorzystanie wspomnianych technologii pozwala na szybkie, łatwe i wielokrotne tworzenie różnych modeli zabudowy w skali architektonicznej i urbanistycznej. Przedstawiona została również redefinicja modelu jednostki sąsiedzkiej w kontekście współczesnych kierunków w mieszkalnictwie. W dysertacji zaproponowano także autorski system oceny walorów przestrzennych zespołów mieszkaniowych. Daje to możliwość formułowania wniosków na temat możliwych kierunków rozwoju obszarów mieszkaniowych i sposobu ich zapisu przez modele cyfrowe oraz zapisy warunkowe wartości wskaźników w dokumentach planistycznych.
Percolation in Networks with Voids and Bottlenecks
Creators: name: Haji-Akbari, Amir
name: Ziff, Robert M.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: A general method is proposed for predicting the asymptotic percolation threshold of networks with bottlenecks, in the limit that the sub-net mesh size goes to zero. The validity of this method is tested for bond percolation on filled checkerboard and "stack-of-triangle" lattices. Thresholds for the checkerboard lattices of different mesh sizes are estimated using the gradient percolation method, while for the triangular system they are found exactly using the triangle-triangle transformation. The values of the thresholds approach the asymptotic values of 0.64222 and 0.53993 respectively as the mesh is made finer, consistent with a direct determination based upon the predicted critical corner-connection probability.
description: to appear, Physical Review E. Small changes from first version
Laser spectroscopic technique for direct identification of a single virus I: FASTER CARS
Creators: name: Deckert, Volker
name: Deckert-Gaudig, Tanja
name: Cialla-May, Dana
name: Popp, Jürgen
name: Zell, Roland
name: Deinhard-Emmer, Stefanie
name: Sokolov, Alexei V.
name: Yi, Zhenhuan
name: Scully, Marlan O.
Publisher: name: Washington, DC : National Acad. of Sciences
Year: 2020
Subjects: subject: coherent anti-Stokes Raman scattering (CARS)
subject: tip-enhanced Raman scattering (TERS)
subject: virus detection
subject: 000
subject: 500

description: From the famous 1918 H1N1 influenza to the present COVID-19 pandemic, the need for improved viral detection techniques is all too apparent. The aim of the present paper is to show that identification of individual virus particles in clinical sample materials quickly and reliably is near at hand. First of all, our team has developed techniques for identification of virions based on a modular atomic force microscopy (AFM). Furthermore, femtosecond adaptive spectroscopic techniques with enhanced resolution via coherent anti-Stokes Raman scattering (FASTER CARS) using tip-enhanced techniques markedly improves the sensitivity [M. O. Scully, et al, Proc. Natl. Acad. Sci. U.S.A. 99, 10994-11001 (2002)].
Measurement of target and double-spin asymmetries for the e- p- →eπ+(n) reaction in the nucleon resonance region at low Q2
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: nucl-ex

description: © 2016 American Physical Society. We report measurements of target- and double-spin asymmetries for the exclusive channel e - p - →eπ+(n) in the nucleon resonance region at Jefferson Lab using the CEBAF Large Acceptance Spectrometer (CLAS). These asymmetries were extracted from data obtained using a longitudinally polarized NH3 target and a longitudinally polarized electron beam with energies 1.1, 1.3, 2.0, 2.3, and 3.0 GeV. The new results are consistent with previous CLAS publications but are extended to a low Q2 range from 0.0065 to 0.35(GeV/c)2. The Q2 access was made possible by a custom-built Cherenkov detector that allowed the detection of electrons for scattering angles as low as 6. These results are compared with the unitary isobar models JANR and MAID, the partial-wave analysis prediction from SAID, and the dynamic model DMT. In many kinematic regions our results, in particular results on the target asymmetry, help to constrain the polarization-dependent components of these models.
Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer's disease-related signaling
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2017
Subjects: Alzheimer Disease
Amyloid Precursor Protein Secretases
Amyloid beta-Peptides
Animals
Cognition Disorders
Corticotropin-Releasing Hormone
Female
GTP-Binding Proteins
Humans
Male
Mice
Mice, Transgenic
Neurons
Phosphorylation
Protein Transport
Receptors, Corticotropin-Releasing Hormone
Sex Factors
Signal Transduction
Stress, Psychological
beta-Arrestin 2

description: Several neuropsychiatric and neurodegenerative disorders share stress as a risk factor and are more prevalent in women than in men. Corticotropin-releasing factor (CRF) orchestrates the stress response, and excessive CRF is thought to contribute to the pathophysiology of these diseases. We previously found that the CRF 1 receptor (CRF 1) is sex biased whereby coupling to its GTP-binding protein, Gs, is greater in females, whereas β-arrestin-2 coupling is greater in males. This study used a phosphoproteomic approach in CRF-overexpressing (CRF-OE) mice to test the proof of principle that when CRF is in excess, sex-biased CRF 1 coupling translates into divergent cell signaling that is expressed as different brain phosphoprotein profiles. Cortical phosphopeptides that distinguished female and male CRF-OE mice were overrepresented in unique pathways that were consistent with Gs-dependent signaling in females and β-arrestin-2 signaling in males. Notably, phosphopeptides that were more abundant in female CRF-OE mice were overrepresented in an Alzheimer's disease (AD) pathway. Phosphoproteomic results were validated by demonstrating that CRF overexpression in females was associated with increased tau phosphorylation and, in a mouse model of AD pathology, phosphorylation of β-secretase, the enzyme involved in the formation of amyloid β. These females exhibited increased formation of amyloid β plaques and cognitive impairments relative to males. Collectively, the findings are consistent with a mechanism whereby the excess CRF that characterizes stress-related diseases initiates distinct cellular processes in male and female brains, as a result of sex-biased CRF 1 signaling. Promotion of AD-related signaling pathways through this mechanism may contribute to female vulnerability to AD.
The PROSPECT physics program
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: reactor neutrino experiments
scintillator detectors
neutrino oscillation
research reactors

description: © 2016 IOP Publishing Ltd. The precision reactor oscillation and spectrum experiment, PROSPECT, is designed to make a precise measurement of the antineutrino spectrum from a highly-enriched uranium reactor and probe eV-scale sterile neutrinos by searching for neutrino oscillations over a distance of several meters. PROSPECT is conceived as a 2-phase experiment utilizing segmented 6Li-doped liquid scintillator detectors for both efficient detection of reactor antineutrinos through the inverse beta decay reaction and excellent background discrimination. PROSPECT Phase I consists of a movable 3 ton antineutrino detector at distances of 7-12 m from the reactor core. It will probe the best-fit point of the disappearance experiments at 4σ in 1 year and the favored region of the sterile neutrino parameter space at in 3 years. With a second antineutrino detector at 15-19 m from the reactor, Phase II of PROSPECT can probe the entire allowed parameter space below 10 eV2 at 5σ in 3 additional years. The measurement of the reactor antineutrino spectrum and the search for short-baseline oscillations with PROSPECT will test the origin of the spectral deviations observed in recent experiments, search for sterile neutrinos, and conclusively address the hypothesis of sterile neutrinos as an explanation of the reactor anomaly.
e-GRASP: An integrated evolutionary and GRASP resource for exploring disease associations
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: Polymorphism
SNP
GWAS
GRASP
Conservation
Disease
Phenotype

description: © 2016 The Author(s). Background: Genome-wide association studies (GWAS) have become a mainstay of biological research concerned with discovering genetic variation linked to phenotypic traits and diseases. Both discrete and continuous traits can be analyzed in GWAS to discover associations between single nucleotide polymorphisms (SNPs) and traits of interest. Associations are typically determined by estimating the significance of the statistical relationship between genetic loci and the given trait. However, the prioritization of bona fide, reproducible genetic associations from GWAS results remains a central challenge in identifying genomic loci underlying common complex diseases. Evolutionary-aware meta-analysis of the growing GWAS literature is one way to address this challenge and to advance from association to causation in the discovery of genotype-phenotype relationships. Description: We have created an evolutionary GWAS resource to enable in-depth query and exploration of published GWAS results. This resource uses the publically available GWAS results annotated in the GRASP2 database. The GRASP2 database includes results from 2082 studies, 177 broad phenotype categories, and ~8.87 million SNP-phenotype associations. For each SNP in e-GRASP, we present information from the GRASP2 database for convenience as well as evolutionary information (e.g., rate and timespan). Users can, therefore, identify not only SNPs with highly significant phenotype-association P-values, but also SNPs that are highly replicated and/or occur at evolutionarily conserved sites that are likely to be functionally important. Additionally, we provide an evolutionary-adjusted SNP association ranking (E-rank) that uses cross-species evolutionary conservation scores and population allele frequencies to transform P-values in an effort to enhance the discovery of SNPs with a greater probability of biologically meaningful disease associations. Conclusion: By adding an evolutionary dimension to the GWAS results available in the GRASP2 database, our e-GRASP resource will enable a more effective exploration of SNPs not only by the statistical significance of trait associations, but also by the number of studies in which associations have been replicated, and the evolutionary context of the associated mutations. Therefore, e-GRASP will be a valuable resource for aiding researchers in the identification of bona fide, reproducible genetic associations from GWAS results. This resource is freely available at http://www.mypeg.info/egrasp.
Heidegger's language
Creators: name: Staples, AJ
Publisher: name: University Of Tasmania
Year: 2023

description: In this dissertation I attempt to provide a cogent reading of Heidegger's fledgling account of the being of language. Emphasis is placed on the analysis of language in Being and Time in particular; for it is with respect to Being and Time that interpretations of Heidegger's fledgling account are developed, and against which his mature account is usually contrasted. Amongst these interpretations are the derivativist and instrumentalist accounts of language, which suppose that language is itself pre-figured by a pre- or non-linguistic grasp of phenomena. Against these accounts, the structure and arguments for which I lay bare, I contend that language is in each case already there, meaningfully articulating the world, affecting understanding ab initio; that language is not therefore prefigured by ‚Äö- and in the first instance absent from ‚Äö- the being-in-the-world which is our own. This, I claim, is also Heidegger's stance; a stance which, formed in Being and Time in essence, founds his subsequent, increasingly dedicated thinking about what language, as such, 'is'. In addition to my critique of instrumentalism and derivativism in this dissertation, I contest the contemporary pragmatist reading of Being and Time inasmuch as it is occasionally employed to champion a non-linguistic normative pragmatism with which to explain just how a non- or pre-linguistic grasp of phenomena might properly occur. As such, this dissertation encourages the reorientation of the philosophy of language (as well as contemporary thinking about Heidegger's own account of the phenomenon) away from the temptation to think language 'formally' according to an hierarchical structure of being-in-the-world, and towards the role and function of language in the structural articulation of the world itself, human being-there, and the hermeneutic tradition in which we inevitably find ourselves to be. As such, it outlines and suggests the possibility and preferability of a phenomenological ‚Äö- as opposed to a metaphysical ‚Äö- account of what language is, attempts to show the universality and ubiquitousness of language in human being, and illustrates the opening 'way' to language qua language which Heidegger's mature thinking was eventually to take.
Regdanvimab: First Approval
Creators: name: Syed, Yahiya Y.
Publisher: name: Adis Journals
Year: 2021
Subjects: Medicine

description: Declarations
Funding The preparation of this review was not supported by any external funding.
Authorship and Conflict of interest During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. Yahiya Y. Syed is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to the review and are responsible for the article content.
Ethics approval, Consent to participate, Consent to publish, Availability of data and material, Code availability not applicable
Additional information about this Adis Drug Review can be found here
Abstract
Regdanvimab (Regkirona™) is a recombinant human monoclonal antibody targeted against the severe acute respiratory syndrome coronavirus 2. It is being developed by Celltrion Inc. for the treatment of coronavirus disease 2019 (COVID-19). In September 2021, regdanvimab received full approval in South Korea for the treatment of COVID-19 in elderly patients aged > 50 years with at least one underlying medical condition (obesity, cardiovascular disease, chronic lung disease, diabetes, chronic kidney disease, chronic liver disease, and patients on immunosuppressive agents) and mild symptoms of COVID-19 and in adult patients with moderate symptoms of COVID-19. This article summarizes the milestones in the development of regdanvimab leading to this first approval for COVID-19.
© Springer Nature Switzerland AG 2021
The standard model of star formation applied to massive stars: accretion disks and envelopes in molecular lines
Creators: name: Keto, Eric
name: Zhang, Qizhou
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We address the question of whether the formation of high-mass stars is similar to or differs from that of solar-mass stars through new molecular line observations and modeling of the accretion flow around the massive protostar IRAS20126+4104. We combine new observations of NH3(1,1) and (2,2) made at the Very Large Array, new observations of CHCN(13-12) made at the Submillimeter Array, previous VLA observations of NH(3,3), NH(4,4), and previous Plateau de Bure observations of C34S(2-1), C34S(5-4), and CHCN(12-11) to obtain a data set of molecular lines covering 15 to 419 K in excitation energy. We compare these observations against simulated molecular line spectra predicted from a model for high-mass star formation based on a scaled-up version of the standard disk-envelope paradigm developed for accretion flows around low-mass stars. We find that in accord with the standard paradigm, the observations require both a warm, dense, rapidly-rotating disk and a cold, diffuse infalling envelope. This study suggests that accretion processes around 10 M stars are similar to those of solar mass stars.
description: Accepted MNRAS
Limits on Active to Sterile Neutrino Oscillations from Disappearance Searches in the MINOS, Daya Bay, and Bugey-3 Experiments
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: Daya Bay Collaboration
MINOS Collaboration

description: © 2016 American Physical Society. Searches for a light sterile neutrino have been performed independently by the MINOS and the Daya Bay experiments using the muon (anti)neutrino and electron antineutrino disappearance channels, respectively. In this Letter, results from both experiments are combined with those from the Bugey-3 reactor neutrino experiment to constrain oscillations into light sterile neutrinos. The three experiments are sensitive to complementary regions of parameter space, enabling the combined analysis to probe regions allowed by the Liquid Scintillator Neutrino Detector (LSND) and MiniBooNE experiments in a minimally extended four-neutrino flavor framework. Stringent limits on sin22θμe are set over 6 orders of magnitude in the sterile mass-squared splitting Δm412. The sterile-neutrino mixing phase space allowed by the LSND and MiniBooNE experiments is excluded for Δm412<0.8 eV2 at 95% CLs.
title: Synthesis and Assembly of Zinc Oxide Microcrystals by a Low‐Temperature Dissolution–Reprecipitation Process: Lessons Learned About Twin Formation in Heterogeneous Reactions
Creators: name: Hoffmann, Rudolf C.
name: Trapp, Maximilian
name: Erdem, Emre
name: Kratzer, Markus
name: Teichert, Christian
name: Kleebe, Hans‐Joachim
name: Schneider, Jörg J.
Publisher: name: Wiley-VCH Verlag GmbH & Co. KGaA
Year: 2022

description: Cobalt-doped zinc oxide single crystals with the shape of hexagonal platelets were synthesized by thermohydrolysis of zinc acetate, cobalt acetate, and hexamethylenetetramine (HMTA) in mixtures of ethanol and water. The mineralization proceeds by a low-temperature dissolution–reprecipitation process from the liquid phase by the formation of basic cobalt zinc salts as intermediates. The crystal shape as well as twin formation of the resulting oxide phase can be influenced by careful choice of the solvent mixture and the amount of doping. An understanding of the course of the reaction was achieved by comprehensive employment of analytical techniques (i.e., SEM, XRD, IR) including an in-depth HRTEM study of precipitates from various reaction stages. In addition, EPR as well as UV/Vis spectroscopic measurements provide information about the insertion of the cobalt dopant into the zincite lattice. The Langmuir–Blodgett (LB) technique is shown to be suitable for depositing coatings of the platelets on glass substrates functionalized with polyelectrolyte multilayers and hence is applied for the formation of monolayers containing domains with ordered tessellation. No major differences are found between deposits on substrates with anionic or cationic surface modification. The adherence to the substrates is sufficient to determine the absolute orientation of the deposited polar single crystals by piezoresponse force microscopy (PFM) and Kelvin probe force microscopy (KPFM) studies.
Series Solution and Minimal Surfaces in AdS
Creators: name: Jevicki, Antal
name: Jin, Kewang
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: According to the Alday-Maldacena program the strong coupling limit of Super Yang-Mills scattering amplitudes is given by minimal area surfaces in AdS spacetime with a boundary consisting of a momentum space polygon. The string equations in AdS systematically reduce to coupled Toda type equations whose Euclidean classical solutions are then of direct relevance. While in the simplest case of AdS_3 exact solutions were known from earlier studies of the sinh-Gordon equation, there exist at present no similar exact forms for the generalized Toda equations related to AdS_d with d>=4. In this paper we develop a series method for the solution to those equations and evaluate their contribution to the finite piece of the worldsheet area. For the known sinh-Gordon case the method is seen to give results in excellent agreement with the exact answer.
description: 19 pages, no figures; references added, one note added
Improved Search for a Light Sterile Neutrino with the Full Configuration of the Daya Bay Experiment
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: Daya Bay Collaboration

description: © 2016 American Physical Society. This Letter reports an improved search for light sterile neutrino mixing in the electron antineutrino disappearance channel with the full configuration of the Daya Bay Reactor Neutrino Experiment. With an additional 404 days of data collected in eight antineutrino detectors, this search benefits from 3.6 times the statistics available to the previous publication, as well as from improvements in energy calibration and background reduction. A relative comparison of the rate and energy spectrum of reactor antineutrinos in the three experimental halls yields no evidence of sterile neutrino mixing in the 2×10-4|Δm412|0.3 eV2 mass range. The resulting limits on sin22θ14 are improved by approx imately a factor of 2 over previous results and constitute the most stringent constraints to date in the |Δm412|0.2 eV2 region.
Quantum Electrodynamics and the Origins of the Exchange, Dipole-Dipole, and Dzyaloshinsky-Moriya Interactions in Itinerant Fermion Systems
Creators: name: Belitz, D.
name: Kirkpatrick, T. R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: It is shown how the exchange interaction, the dipole-dipole interaction, and the Dzyaloshinsky-Moriya interaction between electronic spin-density fluctuations emerge naturally from a field-theoretic framework that couples electrons to the fluctuating electromagnetic potential. Semi-quantitative estimates are given to determine when the dipole-dipole interaction, which is often neglected, needs to be considered, and various applications are discussed, with an emphasis on weak ferromagnets and on helimagnets.
description: 12pp, 3 figs
Oxidation of arsenite to arsenate on birnessite in the presence of light
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: Arsenic remediation
Birnessite
Photochemistry
As(III) oxidation

description: © 2016 The Author(s). The effect of simulated solar radiation on the oxidation of arsenite [As(III)] to arsenate [As(V)] on the layered manganese oxide, birnessite, was investigated. Experiments were conducted where birnessite suspensions, under both anoxic and oxic conditions, were irradiated with simulated solar radiation in the presence of As(III) at pH 5, 7, and 9. X-ray absorption spectroscopy (XAS) was used to determine the nature of the adsorbed product on the surface of the birnessite. The oxidation of As(III) in the presence of birnessite under simulated solar light irradiation occurred at a rate that was faster than in the absence of light at pH 5. At pH 7 and 9, As(V) production was significantly less than at pH 5 and the amount of As(V) production for a given reaction time was the same under dark and light conditions. The first order rate constant (kobs) for As(III) oxidation in the presence of light and in the dark at pH 5 were determined to be 0.07 and 0.04 h-1, respectively. The As(V) product was released into solution along with Mn(II), with the latter product resulting from the reduction of Mn(IV) and/or Mn(III) during the As(III) oxidation process. Post-reaction XAS analysis of As(III) exposed birnessite showed that arsenic was present on the surface as As(V). Experimental results also showed no evidence that reactive oxygen species played a role in the As(III) oxidation process.