cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Computing the Effective Action with the Functional Renormalization Group
Creators: name: Codello, Alessandro
name: Percacci, Roberto
name: Rachwal, Leslaw
name: Tonero, Alberto
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The "exact" or "functional" renormalization group equation describes the renormalization group flow of the effective average action $Γ_k$. The ordinary effective action $Γ_0$ can be obtained by integrating the flow equation from an ultraviolet scale $k=Λ$ down to $k=0$. We give several examples of such calculations at one-loop, both in renormalizable and in effective field theories. We use the results of Barvinsky, Vilkovisky and Avramidi on the non-local heat kernel coefficients to reproduce the four point scattering amplitude in the case of a real scalar field theory with quartic potential and in the case of the pion chiral lagrangian. In the case of gauge theories, we reproduce the vacuum polarization of QED and of Yang-Mills theory. We also compute the two point functions for scalars and gravitons in the effective field theory of scalar fields minimally coupled to gravity.
description: 40 pages
Collaboratively Understanding and Improving Outcomes for the Mother, Fetus, and Infant
Creators: name: Patel, R.M.
name: Manuck, T.A.
Publisher: name: W.B. Saunders
Year: 2018

description: Birth is an incredibly exciting and yet potentially dangerous period for a woman and her fetus, who attempts to navigate the complex transition to neonatal life. Many events during this period establish or disrupt long-lasting health for both the mother and her infant. The challenges during this period are too numerous to quantify, but yield oppor-tunities for prevention and treatment strategies to improve perinatal care and neonatal outcomes. In this issue of Clinics of Perinatology, we highlight these opportunities by including articles that span across obstetrics and neonatology.
(101727) Anna Maria Moore
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Quality Improvement in Perinatal Medicine and Translation of Preterm Birth Research Findings into Clinical Care
Creators: name: Manuck, T.A.
name: McFarlin, B.L.
name: Fry, R.C.
Publisher: name: W.B. Saunders
Year: 2018

description: Billions of dollars are spent yearly in perinatal medicine on studies designed to improve outcomes for mothers and their neonates. However, implementing research findings is challenging and imperfect. Strategies for implementation must be multifaceted and comprehensive. These implementation challenges extend to, and are often greater in, translational and basic science research. The purpose of this review is to discuss current challenges in the provision of quality perinatal and neonatal medical care, particularly those related to preterm birth, and provide examples of prematurity-related perinatal quality collaborative initiatives. Finally, the authors review considerations in implementing both clinical and translational/basic science prematurity research.
title: Head injuries and helmets – a study of the Isle of Man TT motorcycle races
Creators: name: Butt, Muhammad
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Trauma
subject: CNS
subject: CT
subject: Radiation safety
subject: Acute

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The Isle of Man TT (tourist trophy) races are the oldest road races in the world. It is well known that motorcycle racing is a dangerous sport that results in significant morbidity and mortality but despite that TT's attracts hundreds of...
(101723) Albert Spender
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A Family Based Study of Carbon Monoxide and Nitric Oxide Signalling Genes and Preeclampsia
Creators: name: Magnus, P.
name: Yang, J.
name: Luo, J.
name: Morgan, L.
name: Harmon, Q.E.
name: Trogstad, L.
name: Manuck, T.A.
name: Engel, S.M.
name: Wu, M.C.
name: Bauer, A.E.
name: Avery, C.L.
name: Klungsøyr, K.
name: Shi, M.
name: Weinberg, C.R.
name: Williams, N.
name: Olshan, A.F.
name: McGinnis, R.
Publisher: name: Blackwell Publishing Ltd
Year: 2018

description: Background: Preeclampsia is thought to originate during placentation, with incomplete remodelling and perfusion of the spiral arteries leading to reduced placental vascular capacity. Nitric oxide (NO) and carbon monoxide (CO) are powerful vasodilators that play a role in the placental vascular system. Although family clustering of preeclampsia has been observed, the existing genetic literature is limited by a failure to consider both mother and child. Methods: We conducted a nested case–control study within the Norwegian Mother and Child Birth Cohort of 1545 case-pairs and 995 control-pairs from 2540 validated dyads (2011 complete pairs, 529 missing mother or child genotype). We selected 1518 single-nucleotide polymorphisms (SNPs) with minor allele frequency >5% in NO and CO signalling pathways. We used log-linear Poisson regression models and likelihood ratio tests to assess maternal and child effects. Results: One SNP met criteria for a false discovery rate Q-value <0.05. The child variant, rs12547243 in adenylate cyclase 8 (ADCY8), was associated with an increased risk (relative risk [RR] 1.42, 95% confidence interval [CI] 1.20, 1.69 for AG vs. GG, RR 2.14, 95% CI 1.47, 3.11 for AA vs. GG, Q = 0.03). The maternal variant, rs30593 in PDE1C was associated with a decreased risk for the subtype of preeclampsia accompanied by early delivery (RR 0.45, 95% CI 0.27, 0.75 for TC vs. CC; Q = 0.02). None of the associations were replicated after correction for multiple testing. Conclusions: This study uses a novel approach to disentangle maternal and child genotypic effects of NO and CO signalling genes on preeclampsia.
title: Optimised isotropic 3D T1- weighted Spoiled Gradient Echo (SPGR) with Dixon technique for hepatocyte phase imaging at 3T
Creators: name: Nguyen, Bac
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Metastases
subject: Cysts
subject: Cancer
subject: Physics
subject: MR
subject: Pancreas
subject: Oncology
subject: Liver

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of this abstract is highlighting the advantages of an optimised isotropic 3D T1-weighted SPGR Dixon tecnhique for hepatocyte phase imaging at...
title: MR neurography of Piriformis syndrome: A Myth or reality
Creators: name: Vadapalli, Ram Mohan
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neoplasia
subject: Inflammation
subject: Oedema
subject: Diagnostic procedure
subject: MR
subject: Neuroradiology spine
subject: Neuroradiology peripheral nerve
subject: Musculoskeletal soft tissue

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To elucidate the anatomy and pathophysiology and etiological scenarios of Piriformis syndrome and its imaging correlates. Clinical Symptoms and Signs of Piriformis syndrome are illustrated. Common and uncommon pathologies of piriformis syndrome are...
(101721) Charles Spender
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(101722) Louisa Spender
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Epigenetic Regulation of the Nitric Oxide Pathway, 17-α Hydroxyprogesterone Caproate, and Recurrent Preterm Birth
Creators: name: Martin, E.M.
name: Tomlinson, M.S.
name: Smeester, L.
name: Fry, R.C.
name: Varner, M.W.
name: Manuck, T.A.
name: Smith, C.
Publisher: name: Thieme Medical Publishers, Inc.
Year: 2018

description: Objective We sought to evaluate nitric oxide pathway placental gene expression and the epigenome (CpG methylation) among women receiving 17-α hydroxyprogesterone caproate (17-OHPC) with and without recurrent preterm birth (PTB). Study Design This was a case-control study. We prospectively recruited women with ≥ 1 prior singleton spontaneous PTB <34 weeks receiving 17-OHPC. DNA and RNA were isolated from placentas. RNA abundance (gene expression) and the methylome were analyzed for 84 genes in nitric oxide pathways. Women with recurrent PTB <34 weeks (cases) were compared with those delivering at term (controls). Statistical analysis included multivariable models with Bonferroni's corrected p -values. Results In this study, 17 women met inclusion criteria; 7 preterm cases (delivered at 22.6 ± 2.9 weeks) and 10 term controls (delivered at 38.5 ± 0.8 weeks). Groups had similar PTB history, race/ethnicity, and socioeconomic risk factors for PTB. Twenty-seven nitric oxide genes displayed differential expression (p < 0.05 and q < 0.10) when comparing placentas from preterm cases and term controls; all were downregulated in preterm cases. Eight hundred sixty corresponding CpG sites were differentially methylated between the preterm cases and term controls (Bonferroni's p -value <0.05). Conclusion CpG methylation and gene expression patterns in nitric oxide pathway genes differ among placentas from recurrent PTB compared with term birth following 17-OHPC exposure.
Explicit solution to dynamic portfolio choice problem : The continuous-time detour
Creators: name: Legendre, François
name: Togola, Djibril
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Finance (q-fin.CP)
subject: Portfolio Management (q-fin.PM)
subject: Pricing of Securities (q-fin.PR)
subject: Statistical Finance (q-fin.ST)
subject: FOS: Economics and business

description: This paper solves the dynamic portfolio choice problem. Using an explicit solution with a power utility, we construct a bridge between a continuous and discrete VAR model to assess portfolio sensitivities. We find, from a well analyzed example that the optimal allocation to stocks is particularly sensitive to Sharpe ratio. Our quantitative analysis highlights that this sensitivity increases when the risk aversion decreases and/or when the time horizon increases. This finding explains the low accuracy of discrete numerical methods especially along the tails of the unconditional distribution of the state variable.
The Oxytocin Product Correlates with Total Oxytocin Received during Labor: A Research Methods Study
Creators: name: Seco, A.
name: Grotegut, C.A.
name: James, A.H.
name: Allen, T.K.
name: Manuck, T.A.
name: Lewis, L.L.
name: Deneux-Tharaux, C.
Publisher: name: Thieme Medical Publishers, Inc.
Year: 2018

description: Objective Total dose of oxytocin received during labor is an important variable in studies of human labor but is difficult to calculate. We sought to identify a surrogate measure for total dose of oxytocin received. Study Design For each subject receiving oxytocin during labor, the oxytocin total dose received in labor was calculated as the area under the curve. Maximal oxytocin infusion rate, total duration of oxytocin infusion, and the product of both, defined as the oxytocin product, were then each correlated with the total dose of oxytocin received using the Pearson's correlation coefficient. Results Oxytocin dosing data were available from 402 women at Duke and 6,907 women from Pithagore6. The two variables alone, or combined as the oxytocin product, demonstrated a high correlation with the oxytocin total dose (r > 0.7), with the oxytocin product demonstrating the highest (r > 0.9). This was true whether labor was induced or augmented and whether delivery was vaginal or cesarean. Conclusion The oxytocin product, composed of two easily obtained variables, demonstrated a very high correlation with total oxytocin dose received in labor and represents a simple and accurate surrogate for total dose of oxytocin received during labor. The oxytocin product can be used in clinical studies in which oxytocin dose is an important variable.
Το σύγχρονο ελληνικό φαρμακείο τον 21ο αιώνα
Creators: name: Παππά, Ζαχαρούλα
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2023
Subjects: subject: Φαρμακείο
subject: Φαρμακοποιός
subject: Μέλλον

description: Το φαρμακείο αποτελεί το διαχρονικό φορέα στον οποίο θα απευθυνθεί πρωτίστως ο ασθενής για να αναφέρει κάποιο πρόβλημα υγείας που τον απασχολεί και να ζητήσει συμβουλές. Με τον τρόπο αυτό συνεισφέρει στη διατήρηση της υγείας του κοινωνικού συνόλου είτε άμεσα, προσφέροντας λύση στο πρόβλημα του, είτε έμμεσα κατευθύνοντας σωστά τον ασθενή στην εύρεση της καλύτερης δυνατής λύσης στο πρόβλημα. Για να είναι βιώσιμο το σύγχρονο φαρμακείο πρέπει να είναι σε θέση να συνεχίσει να εξελίσσεται και να ανακαλύπτει διαρκώς νέους τρόπους για να ανταποκριθεί στις ανάγκες των ασθενών. Η σύγχρονη πρακτική του φαρμακείου περιστρέφεται γύρω από τη φροντίδα των ασθενών: αξιολόγηση, συνταγογράφηση, παρακολούθηση και εκπαίδευση. Ο ρόλος του φαρμακοποιού είναι να αφουγκράζεται τις εξελίξεις και τις ανάγκες του πληθυσμού που εξυπηρετεί και να βρίσκει τρόπους να καινοτομεί με τις δράσεις του. Οι πρόσφατες μεταρρυθμίσεις του εθνικού συστήματος υγείας, μαζί με μια άνευ προηγουμένου εποχή τεχνολογικών, οικονομικών και δημογραφικών εξελίξεων παρουσιάζουν τόσο προκλήσεις όσο και ευκαιρίες για το φαρμακευτικό επάγγελμα. Υπάρχουν πολλά οράματα για το φαρμακείο του μέλλοντος και πολλά νέα μοντέλα άσκησης του επαγγέλματος, ωστόσο δεν έχουν καταφέρει να συμπληρωθούν σε ένα συνεκτικό πρότυπο για τον ρόλο που θα παίξει το φαρμακείο στο ελληνικό εθνικό σύστημα υγείας. Σκοπός της συγκεκριμένης εργασίας είναι η μελέτη του φαρμακείου σήμερα και η προσπάθεια πρόβλεψης του φαρμακείου στο εγγύς μέλλον. Η εκπόνηση αυτής της εργασίας έχει στόχο να αποτελέσει την αφετηρία και για άλλες εργασίες πάνω στον τομέα των φαρμακείων καθώς και να αξιοποιηθεί ως ένα σύγχρονο και επικαιροποιημένο εργαλείο για την πορεία που πρέπει να ακολουθήσουν τα φαρμακεία και οι φαρμακοποιοί ώστε να ανταποκριθούν στις ανανεωμένες ανάγκες των ασθενών και του συστήματος υγείας.
title: Ultrasound imaging of Lisfranc ligament - examination technique, anatomy, injuries.
Creators: name: Olchowy, Cyprian
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Anatomy
subject: Musculoskeletal soft tissue
subject: Musculoskeletal system
subject: Ultrasound
subject: Education
subject: Education and training
subject: Athletic injuries

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The objectives of this presentation are: To become familiar with normal anatomy of Lisfranc ligament (educational illustrations) To present ultrasound scanning technique and high-quality ultrasound images. To become familiar with typical mechanisms...
Lipoprotein particle concentration measured by nuclear magnetic resonance spectroscopy is associated with gestational age at delivery: a prospective cohort study
Creators: name: Herring, A.H.
name: Vladutiu, C.J.
name: Grace, M.R.
name: Thorp, J.T.
name: Savitz, D.
name: Manuck, T.A.
name: Nethery, R.C.
name: Siega-Riz, A.M.
Publisher: name: Blackwell Publishing Ltd
Year: 2018

description: Objective: To estimate the association between lipoprotein particle concentrations in pregnancy and gestational age at delivery. Design: Prospective cohort study. Setting: The study was conducted in the USA at the University of North Carolina. Population: We assessed 715 women enrolled in the Pregnancy, Infection, and Nutrition study from 2001 to 2005. Methods: Fasting blood was collected at two time points (<20 and 24–29 weeks of gestation). Nuclear magnetic resonance (NMR) quantified lipoprotein particle concentrations [low-density lipoprotein (LDL), high-density lipoprotein (HDL), very-low density lipoprotein (VLDL)] and 10 subclasses of lipoproteins. Concentrations were assessed as continuous measures, with the exception of medium HDL which was classified as any or no detectable level, given its distribution. Cox proportional hazards models estimated hazard ratios (HR) for gestational age at delivery adjusting for covariates. Main outcome measures: Gestational age at delivery, preterm birth (<37 weeks of gestation), and spontaneous preterm birth. Results: At <20 weeks of gestation, three lipoproteins were associated with later gestational ages at delivery [large LDL NMR (HR 0.78, 95% CI 0.64–0.96), total VLDL NMR (HR 0.77, 95% CI 0.61–0.98), and small VLDL NMR (HR 0.78, 95% CI 0.62–0.98], whereas large VLDL NMR (HR 1.19, 95% CI 1.01–1.41) was associated with a greater hazard of earlier delivery. At 24–28 weeks of gestation, average VLDL NMR (HR 1.25, 95% CI 1.03–1.51) and a detectable level of medium HDL NMR (HR 1.90, 95% CI 1.19–3.02) were associated with earlier gestational ages at delivery. Conclusion: In this sample of pregnant women, particle concentrations of VLDL NMR , LDL NMR , IDL NMR , and HDL NMR were each independently associated with gestational age at delivery for all deliveries or spontaneous deliveries <37 weeks of gestation. These findings may help formulate hypotheses for future studies of the complex relationship between maternal lipoproteins and preterm birth. Tweetable abstract: Nuclear magnetic resonance spectroscopy may identify lipoprotein particles associated with preterm delivery.
(101724) Augustus Stevens
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Thoracic Manifestations of Amyloidosis in Cross Sectional Imaging
Creators: name: Au Yong, Tracy
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Education and training
subject: Education
subject: MR
subject: CT
subject: Lung
subject: Cardiac

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: This pictoral review aims to demonstrate the recognized patterns of cross-sectional abnormalities in thoracic...
Revisiting the vortex-core tunnelling spectroscopy in YBa$_2$Cu$_3$O$_{7-δ}$
Creators: name: Bruér, Jens
name: Maggio-Aprile, Ivan
name: Jenkins, Nathan
name: Ristić, Zoran
name: Erb, Andreas
name: Berthod, Christophe
name: Fischer, Øystein
name: Renner, Christoph
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The observation by scanning tunnelling spectroscopy (STS) of Abrikosov vortex cores in the high-temperature superconductor YBa$_2$Cu$_3$O$_{7-δ}$ (Y123) has revealed a robust pair of electron-hole symmetric states at finite subgap energy. Their interpretation remains an open question because theory predicts a different signature in the vortex cores, characterised by a strong zero-bias conductance peak. We present STS data on very homogeneous Y123 at 0.4 K revealing that the subgap features do not belong to vortices: they are actually observed everywhere along the surface with high spatial and energy reproducibility, even in the absence of magnetic field. Detailed analysis and modelling show that these states remain unpaired in the superconducting phase and belong to an incoherent channel which contributes to the tunnelling signal in parallel with the superconducting density of states.
description: Final version with supplementary material
title: Preoperative imaging of potential renal transplant recipients
Creators: name: El-Diasty, Mohamed
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Kidney
subject: Urinary Tract / Bladder
subject: CT
subject: Ultrasound
subject: Fluoroscopy
subject: Diagnostic procedure
subject: Transplantation

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review the role of different imaging modalities in the pre-surgical assessment of potential renal transplant recipients. Provide a suggested imaging approach and checklist for imaging end-stage renal disease ERSD...
Pharmacogenomics of 17-alpha hydroxyprogesterone caproate for recurrent preterm birth: a case–control study
Creators: name: Saade, G.
name: Esplin, M.S.
name: Jorde, L.B.
name: Bukowski, R.
name: The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Genomics and Proteomics Network for Preterm Birth Research (GPN-PBR)
name: Ilekis, J.
name: Sadovsky, Y.
name: Biggio, J.
name: Reddy, U.M.
name: Andrews, W.
name: Yandell, M.
name: Manuck, T.A.
name: Zhan, H.
name: Parry, S.
name: Watkins, W.S.
name: Huang, H.
name: Varner, M.W.
Publisher: name: Blackwell Publishing Ltd
Year: 2018

description: Objective: To compare maternal genotypes between women with and without significant prolongation of pregnancy in the setting of 17-alpha hydroxyprogesterone caproate (17-P) administration for the prevention of recurrent preterm birth (PTB). Design: Case–control. Setting: Three tertiary-care centres across the USA. Population: Women (n = 99) with ≥ 1 prior singleton spontaneous PTB, receiving 17-P. Methods: Women were classified as having successful prolongation of pregnancy during the 17-P treated pregnancy, in two ways: (1) Definition A: success/non-success based on difference in gestational age at delivery between 17-P-treated and untreated pregnancies (success: delivered ≥ 3 weeks later with 17-P) and (2) Definition B: success/non-success based on reaching term (success: delivered at term with 17-P). Main outcome measures: To assess genetic variation, all women underwent whole exome sequencing. Between-group sequence variation was analysed with the Variant Annotation, Analysis, and Search Tool (VAAST). Genes scored by VAAST with P < 0.05 were then analysed with two online tools: (1) Protein ANalysis THrough Evolutionary Relationships (PANTHER) and (2) Database for Annotation, Visualization, and Integrated Discovery (DAVID). Results: Using Definition A, there were 70 women with successful prolongation and 29 without; 1375 genes scored by VAAST had P < 0.05. Using Definition B, 47 women had successful prolongation and 52 did not; 1039 genes scored by VAAST had P < 0.05. PANTHER revealed key differences in gene ontology pathways. Many genes from definition A were classified as prematurity genes (P = 0.026), and those from definition B as pharmacogenetic genes (P = 0.0018); (P, non-significant after Bonferroni correction). Conclusion: A novel analytic approach revealed several genetic differences among women delivering early vs later with 17-P. Tweetable abstract: Several key genetic differences are present in women with recurrent preterm birth despite 17-P treatment.
(101719) Elizabeth Smith
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The distribution of work performed on a NIS junction
Creators: name: Santos, Jaime E.
name: Ribeiro, Pedro
name: Kirchner, Stefan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We propose an experimental setup to measure the work performed in a normal-metal/insulator/superconducting (NIS) junction, subjected to a voltage change and in contact with a thermal bath. We compute the performed work and argue that the associated heat release can be measured experimentally. Our results are based on an equivalence between the dynamics of the NIS junction and that of an assembly of two-level systems subjected to a circularly polarised field, for which we can determine the work-characteristic function exactly. The average work dissipated by the NIS junction, as well as its fluctuations, are determined. From the work characteristic function, we also compute the work probability-distribution and show that it does not have a Gaussian character. Our results allow for a direct experimental test of the Crooks-Tasaki fluctuation relation.
description: 30 pages, 2 figures
Screening for spontaneous preterm birth and resultant therapies to reduce neonatal morbidity and mortality: A review
Creators: name: Manuck, T.A.
name: Glover, A.V.
Publisher: name: W.B. Saunders Ltd
Year: 2018

description: Despite considerable effort aimed at decreasing the incidence of spontaneous preterm birth, it remains the leading cause of perinatal morbidity and mortality. Screening strategies are imperfect. Approaches used to identify women considered by historical factors to be low risk for preterm delivery (generally considered to be women with singleton pregnancies without a history of a previous preterm birth) as well as those at high risk for preterm birth (those with a previous preterm birth, short cervix, or multiple gestation) continue to evolve. Herein, we review the current evidence and approaches to screening women for preterm birth, and examine future directions for clinical practice. Further research is necessary to better identify at-risk women and provide evidence-based management.
(101720) Elizabeth Smith
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
RXTE/HEXTE Analysis of the Crab Pulsar Glitch of July 2000
Creators: name: Vivekanand, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Hard xray data from the RXTE observatory (HEXTE energy range 15 to 240 keV) have been analyzed to obtain a phase coherent timing solution for the Crab pulsar glitch of 15 July 2000. The results are: (1) step change in the rotation frequency $ν_0$ of the Crab pulsar at the epoch of the glitch is $Δν_0 = (30 \pm 3) \times 10^{-9} \times ν_0$, (2) step change in its time derivative is $Δ\dot ν_0 = (4.8 \pm 0.6) \times 10^{-3} \times \dot ν_0$, and (3) the time scale of decay of the the step change is $τ_d = 4.7 \pm 0.5$ days. The first two results are consistent with those obtained at radio frequencies by the Jodrell Bank observatory. The last result has not been quoted in the literature, but could be an underestimate due to lack of observations very close to the glitch epoch. By comparing with the monthly timing ephemeris published by the Jodrell group for the Crab pulsar, the time delay between the main peaks of the hard xray and radio pulse profiles is estimated to be $+411 \pm 167$ $μ$sec. Although this number is not very significant, it is consistent with the number derived for the 2 to 16 keV energy range, using the PCA instrument of RXTE. The separation between the two peaks of the integrated pulse profile of the Crab pulsar, and the ratio of their intensities, both are statistically similar before and after the glitch. The dead time corrected integrated photon flux within the integrated pulse profile appears to decrease after the glitch, although this is not a statistically strong result. This work achieves what can be considered to be almost absolute timing analysis of the Crab pulsar hard xray data.
description: Accepted for publication by ApJ on 28 Mar 2015
title: MR diagnostics of adnexal masses
Creators: name: Nikolic, Olivera
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Pelvis
subject: MR
subject: Imaging sequences
subject: Neoplasia
subject: Metastases
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: This lecture will cover: 1. MRI indications, 2. patient preparation, 3. protocol and 4. categorization of adnexal masses. Variety of selected cases will be...
title: Bowel disease in patients with HIV-positive patients: evaluation with CT.
Creators: name: Sokolina, Irina
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Lymphoma
subject: Infection
subject: AIDS
subject: Endoscopy
subject: Contrast agent-oral
subject: Contrast agent-intravenous
subject: Image manipulation / Reconstruction
subject: CT
subject: Conventional radiography
subject: Lymph nodes
subject: Colon
subject: Abdomen

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The World Health Organization (WHO) identified HIV/AIDS as the world`s most urgent public health challenge, as AIDS represents the greatest lethal epidemic in recent history. The gastrointestinal (GI) tracts is a major site of disease in HIV...
Some results on equivariant contact geometry for partial flag varieties
Creators: name: Crooks, Peter
name: Rayan, Steven
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: Algebraic Geometry (math.AG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 32M10 (primary), 14J45, 14M15, 22F30, 53D10 (secondary)

description: We study equivariant contact structures on complex projective varieties arising as partial flag varieties $G/P$, where $G$ is a connected, simply-connected complex simple group of type $ADE$ and $P$ is a parabolic subgroup. We prove a special case of the LeBrun-Salamon conjecture for partial flag varieties of these types. The result can be deduced from Boothby's classification of compact simply-connected complex contact manifolds with transitive action by contact automorphisms, but our proof is completely independent and relies on properties of $G$-equivariant vector bundles on $G/P$. A byproduct of our argument is a canonical, global description of the unique $SO_{2n}(\mathbb C)$-invariant contact structure on the isotropic Grassmannian of $2$-planes in $\mathbb C^{2n}$.
description: 11 pages
Maternal race and intergenerational preterm birth recurrence
Creators: name: Miles, G.
name: Manuck, T.A.
name: Grant, J.H.
name: Smid, M.C.
name: Chapman, D.A.
name: Lee, J.H.
name: Stoddard, G.J.
Publisher: name: Mosby Inc.
Year: 2017

description: Background Preterm birth is a complex disorder with a heritable genetic component. Studies of primarily White women born preterm show that they have an increased risk of subsequently delivering preterm. This risk of intergenerational preterm birth is poorly defined among Black women. Objective Our objective was to evaluate and compare intergenerational preterm birth risk among non-Hispanic Black and non-Hispanic White mothers. Study Design This was a population-based retrospective cohort study, using the Virginia Intergenerational Linked Birth File. All non-Hispanic Black and non-Hispanic White mothers born in Virginia 1960 through 1996 who delivered their first live-born, nonanomalous, singleton infant ≥20 weeks from 2005 through 2009 were included. We assessed the overall gestational age distribution between non-Hispanic Black and White mothers born term and preterm (<37 weeks) and their infants born term and preterm (<37 weeks) using Cox regression and Kaplan-Meier survivor functions. Mothers were grouped by maternal gestational age at delivery (term, ≥37 completed weeks; late preterm birth, 34-36 weeks; and early preterm birth, <34 weeks). The primary outcomes were: (1) preterm birth among all eligible births; and (2) suspected spontaneous preterm birth among births to women with medical complications (eg, diabetes, hypertension, preeclampsia and thus higher risk for a medically indicated preterm birth). Multivariable logistic regression was used to estimate odds of preterm birth and spontaneous preterm birth by maternal race and maternal gestational age after adjusting for confounders including maternal education, maternal age, smoking, drug/alcohol use, and infant gender. Results Of 173,822 deliveries captured in the intergenerational birth cohort, 71,676 (41.2%) women met inclusion criteria for this study. Of the entire cohort, 30.0% (n = 21,467) were non-Hispanic Black and 70.0% were non-Hispanic White mothers. Compared to non-Hispanic White mothers, non-Hispanic Black mothers were more likely to have been born late preterm (6.8% vs 3.7%) or early preterm (2.8 vs 1.0%), P <.001. Non-Hispanic White mothers who were born (early or late) preterm were not at an increased risk of early or late preterm delivery compared to non-Hispanic White mothers born term. The risk of early preterm birth was most pronounced for Black mothers who were born early preterm (adjusted odds ratio, 3.26; 95% confidence interval, 1.77–6.02) compared to non-Hispanic White mothers. Conclusion We found an intergenerational effect of preterm birth among non-Hispanic Black mothers but not non-Hispanic White mothers. Black mothers born <34 weeks carry the highest risk of delivering their first child very preterm. Future studies should elucidate the underlying pathways leading to this racial disparity.
A model for melting of confined DNA
Creators: name: Werner, E.
name: Reiter-Schad, M.
name: Ambjörnsson, T.
name: Mehlig, B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biomolecules (q-bio.BM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: When DNA molecules are heated they denature. This occurs locally so that loops of molten single DNA strands form, connected by intact double-stranded DNA pieces. The properties of this "melting" transition have been intensively investigated. Recently there has been a surge of interest in this question, caused by experiments determining the properties of partially bound DNA confined to nanochannels. But how does such confinement affect the melting transition? To answer this question we introduce, and solve a model predicting how confinement affects the melting transition for a simple model system by first disregarding the effect of self-avoidance. We find that the transition is smoother for narrower channels. By means of Monte-Carlo simulations we then show that a model incorporating self-avoidance shows qualitatively the same behaviour and that the effect of confinement is stronger than in the ideal case.
description: 5 pages, 4 figures, supplementary material
21cm-line bispectrum as method to probe Cosmic Dawn and Epoch of Reionization
Creators: name: Shimabukuro, Hayato
name: Yoshiura, Shintaro
name: Takahashi, Keitaro
name: Yokoyama, Shuichiro
name: Ichiki, Kiyotomo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Redshifted 21cm signal is a promising tool to investigate the state of intergalactic medium (IGM) in the Cosmic Dawn (CD) and Epoch of Reionization(EoR). In our previous work (Shimabukuro et al 2015), we studied the variance and skewness to give a clear interpretation of 21cm power spectrum and found that skewness is a good indicator of the epoch when X-ray heating becomes effective. Thus, the non-Gaussian feature of the spatial distribution of the 21cm signal is expected to be useful to investigate the astrophysical effects in the CD and EoR. In this paper, in order to investigate such a non-Gaussian feature in more detail, we focus on the bispectrum of the 21cm signal. It is expected that the 21cm brightness temperature bispectrum is produced by non-gaussianity due to the various astrophysical effects such as Wouthysen-Field (WF) effect, X-ray heating and reionization. We study the various properties of 21cm bispectrum such as scale dependence, shape dependence and redshift evolution. And also we study the contribution from each component of 21cm bispectrum. We find that the contribution from each component has characteristic scale-dependent feature, and it is expected that we could obtain more detailed information on the IGM in the CD and EoR by using the 21cm bispectrum in the future experiments, combined with the power spectrum and skewness.
description: 11 pages, 7 figures, published in MNRAS
title: Creutzfeldt-Jakob Disease…exploring new fields.
Creators: name: Gatt, Simon
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Dementia
subject: Education
subject: MR-Diffusion/Perfusion
subject: MR
subject: Neuroradiology brain
subject: Infection

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To delineate the various types of Creutzfeldt-Jakob Disease (CJD) with particular emphasis on the sporadic variant. To highlight the main presenting features of this neurodegenerative disease and define the most important diagnostic criteria. To...
Quantum Darwinism and non-Markovian dissipative dynamics from quantum phases of the spin-1/2 XX model
Creators: name: Giorgi, Gian Luca
name: Galve, Fernando
name: Zambrini, Roberta
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum Darwinism explains the emergence of a classical description of objects in terms of the creation of many redundant registers in an environment containing their classical information. This amplification phenomenon, where only classical information reaches the macroscopic observer and through which different observers can agree on the objective existence of such object, has been revived lately for several types of situations, successfully explaining classicality. We explore quantum Darwinism in the setting of an environment made of two level systems which are initially prepared in the ground state of the XX model, which exhibits different phases; we find that the different phases have different ability to redundantly acquire classical information about the system, being the "ferromagnetic phase" the only one able to complete quantum Darwinism. At the same time we relate this ability to how non-Markovian the system dynamics is, based on the interpretation that non-Markovian dynamics is associated to back flow of information from environment to system, thus spoiling the information transfer needed for Darwinism. Finally, we explore mixing of bath registers by allowing a small interaction among them, finding that this spoils the stored information as previously found in the literature.
Il procedimento sanzionatorio Consob alla luce delle recenti evoluzioni legislative e giurisprudenziali
Creators: name: TOSA, ALESSANDRA
Publisher: name: Universit� degli studi di Genova
Year: 2019

description: Consob sanctioning proceeding was subject to considerable and recent legislative changes in the last few years. Regulatory innovation is basically due to the increasingly significant role of the ?ex post? Authority?s enforcement concerning the financial markets on the one hand, and the constantly evolving jurisprudential application at national and supernational level, on the other. This relates mainly to the evolution of the concept of ?sanction? and essential corollaries stemming from its legal qualification such as the application of the principle of fair trial, the unfolding of the so-called ?ne bis in idem?, the peculiarities of ?double track? sanctions in market abuse. It is an aim of this research work to understand if the currently exsisting ?ex post? Consob enforcement and its sanctioning proceeding is sufficiently effective in terms of deterrence and procedural safeguards.
Correlation functions in conformal invariant stochastic processes
Creators: name: Alcaraz, Francisco C.
name: Rittenberg, Vladimir
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider the problem of correlation functions in the stationary states of one-dimensional stochastic models having conformal invariance. If one considers the space dependence of the correlators, the novel aspect is that although one considers systems with periodic boundary conditions, the observables are described by boundary operators. From our experience with equilibrium problems one would have expected bulk operators. Boundary operators have correlators having critical exponents being half of those of bulk operators. If one studies the space-time dependence of the two-point function, one has to consider one boundary and one bulk operators. The Raise and Peel model has conformal invariance as can be shown in the spin 1/2 basis of the Hamiltonian which gives the time evolution of the system. This is an XXZ quantum chain with twisted boundary condition and local interactions. This Hamiltonian is integrable and the spectrum is known in the finite-size scaling limit. In the stochastic base in which the process is defined, the Hamiltonian is not local anymore. The mapping into an SOS model, helps to define new local operators. As a byproduct some new properties of the SOS model are conjectured. The predictions of conformal invariance are discussed in the new framework and compared with Monte Carlo simulations.
description: 21 pages, 11 figures
Maternal obesity and major intraoperative complications during cesarean delivery
Creators: name: Stamilio, D.M.
name: Smid, M.C.
name: Vladutiu, C.J.
name: Dotters-Katz, S.K.
name: Boggess, K.A.
name: Manuck, T.A.
Publisher: name: Mosby Inc.
Year: 2017

description: Background Multiple studies have demonstrated an association between maternal obesity and postoperative complications, but there is a dearth of information about the impact of obesity on intraoperative complications. Objective To estimate the association between maternal obesity at delivery and major intraoperative complications during cesarean delivery (CD). Methods This is a secondary analysis of the deidentified Maternal-Fetal Medicine Unit Cesarean Registry of women with singleton pregnancies. Maternal body mass index (BMI) at delivery was categorized as BMI 18.5 to 29.9 kg/m2, BMI 30 to 39.9 kg/m2, BMI 40 to 49.9 kg/m2, and BMI ≥ 50 kg/m2. The primary outcome, any intraoperative complication, was defined as having at least 1 major intraoperative complication, including perioperative blood transfusion, intraoperative injury (bowel, bladder, ureteral injury; broad ligament hematoma), atony requiring surgical intervention, repeat laparotomy, and hysterectomy. Log-binomial models were used to estimate risk ratios of intraoperative complication in 2 models: model 1 adjusting for maternal race, and preterm delivery <37 weeks; and model 2 adjusting for confounders in Model 1 as well as emergency CD, and type of skin incision. Results A total of 51,218 women underwent CD; 38% had BMI 18.5 to 29.9 kg/m2, 47% BMI 30 to 39.9 kg/m2, 12% BMI 40 to 49.9 kg/m2 and 3% BMI ≥ 50 kg/m2. Having at least 1 intraoperative complication was uncommon (3.4%): 3.8% for BMI 18.5 to 29.9 kg/m2, 3.2% BMI 30 to 39.9 kg/m2, 2.6% BMI 40 to 49.9 kg/m2 and 4.3% BMI ≥ 50 kg/m2 (P < .001). In the fully adjusted model 2, women with BMI 40 to 49.9 kg/m2 had a lower risk of any intraoperative complication (adjusted risk ratio [ARR], 0.76; 95% confidence interval [CI], 0.64 to 0.89) compared with women with BMI 18.5 to 29.9 kg/m2. Women with BMI 30 to 39.9 kg/m2 (ARR, 0.93; 95% CI, 0.84 to 1.03) had a similar risk of any intraoperative complication compared with nonobese women. Among super obese women, there was evidence of effect modification by emergency CD. Compared with nonobese women, neither super obese women undergoing nonemergency CD (ARR, 1.13; 95% CI, 0.84 to 1.52) nor those undergoing emergency CD (ARR, 0.59; 95% CI, 0.32 to 1.10) had an increased risk of intraoperative complication. Conclusion In contrast to the risk for postcesarean complications, the risk of intraoperative complication does not appear to be increased in obese women, even among those with super obesity.