cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Synthesis, DFT and In Silico Anti-COVID Evaluation of Novel Tetrazole Analogues
Creators: name: Devasia, Jyothis
name: Chinnam, Sampath
name: Khatana, Kavita
name: Shakya, Sonam
name: Joy, Francis
name: Rudrapal, Mithun
name: Nizam, Aatika
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biophysics
Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: A new series of 3-aryl/heteroaryl-2-(1H-tetrazol-5-yl) acrylamides have been synthesized through catalyst-free, one-pot cascade reactions, utilizing click chemistry approach and evaluated for their anti-COVID activities against two proteins in silico. The structural properties of the synthesized molecules were evaluated based on DFT calculations. Total energy of the synthesized tetrazole compounds were obtained through computational analysis which indicate the high stability of the synthesized compounds. The Frontier Molecular Orbitals (FMO) and associated energies and molecular electrostatic potential (MEP) surfaces were generated for the compounds. Spectral analysis by DFT gave additional evidence to the structural properties of the synthesized molecules. All tetrazole analogues come under good ADMET data as they followed the standard value for ADMET parameters. Docking studies offered evidence of the molecules displaying excellent biological properties as an anti-Covid drug. Compound 4 g exhibited excellent anti-COVID-19 properties with four hydrogen binding interactions with amino acids GLN 2.486 Å, GLN 2.436 Å, THR 2.186 Å and HSD 2.468 Å with good full-fitness score (–1189.12) and DeltaG (–7.19). Similarly, compound 4d shown potent activity against anti-COVID-19 mutant protein (PDB: 3K7H) with three hydrogen binding interactions, i.e., SER 2.274 Å, GLU 1.758 Å and GLU 1.853 Å with full-fitness score of –786.60) and DeltaG (–6.85). The result of these studies revealed that the compounds have the potential to become lead molecules in the drug discovery process.
Non-Absoluteness of Model Existence at $\aleph_ω$
Creators: name: Milovich, David
name: Souldatos, Ioannis
Publisher: name: arXiv
Year: 2017
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 03C48, 03C55 (Primary) 03E35, 03E55, 03C52, 03C75 (Secondary)

description: In [FHK13], the authors considered the question whether model-existence of $L_{ω_1,ω}$-sentences is absolute for transitive models of ZFC, in the sense that if $V \subseteq W$ are transitive models of ZFC with the same ordinals, $φ\in V$ and $V\models "φ\text{ is an } L_{ω_1,ω}\text{-sentence}"$, then $V \models "φ\text{ has a model of size } \aleph_α"$ if and only if $W \models "φ\text{ has a model of size } \aleph_α"$. From [FHK13] we know that the answer is positive for $α=0,1$ and under the negation of CH, the answer is negative for all $α>1$. Under GCH, and assuming the consistency of a supercompact cardinal, the answer remains negative for each $α>1$, except the case when $α=ω$ which is an open question in [FHK13]. We answer the open question by providing a negative answer under GCH even for $α=ω$. Our examples are incomplete sentences. In fact, the same sentences can be used to prove a negative answer under GCH for all $α>1$ assuming the consistency of a Mahlo cardinal. Thus, the large cardinal assumption is relaxed from a supercompact in [FHK13] to a Mahlo cardinal. Finally, we consider the absoluteness question for the $\aleph_α$-amalgamation property of $L_{ω_1,ω}$-sentences (under substructure). We prove that assuming GCH, $\aleph_α$-amalgamation is non-absolute for $1
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Cart. 189 (11 H 74), 316 folios, f. 0263r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0263r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0263r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
An EPQ model with time proportion deterioration and ramp type demand under different payment schemes with fuzzy uncertainties
Creators: name: Supakar, Puja
name: Mahato, Sanat Kumar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: To ensure the order of goods and to attract the retailers and small vendors through discounts, the advance payment is a well-practised real life phenomenon in present market scenario and is being well studied in the field of inventory modelling and supply chain. Almost all inventory models depend upon the demands of the customers. Thus, demand is an important characteristic. The items may decay or deteriorate with time and loss their values partly or in full. The parameters might fluctuate due to various reasons and is more realistic to consider the uncertainty of the parameters rather than their fixed values. A deteriorating inventory model for a single item without shortage is developed in this paper. The crisp models are developed without and with advance payment schemes having time dependent ramp type demand and time proportion deterioration rate. The corresponding fuzzy models are formulated in which several parameters involved are taken as pentagonal fuzzy numbers to incorporate the uncertainties. We used the Regular Weighted Point method to convert the fuzzy numbers into the crisp numbers in order to make the computations affordable. We presented some numerical examples and studied the changing effects of different inventory parameters. Managerial insights are also described.
Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies
Creators: name: Iqbal, Jamshed
name: El-Gamal, Mohammed I.
name: Ejaz, Syeda Abida
name: Lecka, Joanna
name: Sévigny, Jean
name: Oh, Chang-Hyun
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 60506 Virology

description: Tissue-nonspecific alkaline phosphatase (TNAP) is an important isozyme of alkaline phosphatases, which plays different pivotal roles within the human body. Most importantly, it is responsible for maintaining the balanced ratio of phosphate and inorganic pyrophosphate, thus regulates the extracellular matrix calcification during bone formation and growth. The elevated level of TNAP has been linked to vascular calcification and end-stage renal diseases. Consequently, there is a need to search for highly potent and selective inhibitors of alkaline phosphatases (APs) for treatment of disorders associated with the over-expression of APs. Herein, a series of tricyclic coumarin sulphonate 1a-za with known antiproliferative activity, was evaluated for AP inhibition against human tissue nonspecific alkaline phosphatase (h-TNAP) and human intestinal alkaline phosphatase (h-IAP). The methylbenzenesulphonate derivative 1f (IC50 = 0.38 ± 0.01 μM) was found to be the most active h-TNAP inhibitor. Another 4-fluorobenzenesulphonate derivative 1i (IC50 = 0.45 ± 0.02 μM) was found as the strongest inhibitor of h-IAP. Some of the derivatives were also identified as highly selective inhibitors of APs. Detailed structure-activity relationship (SAR) was investigated to identify the functional groups responsible for the effective inhibition of AP isozymes. The study was also supported by the docking studies to rationalise the most possible binding site interactions of the identified inhibitors with the targeted enzymes.
Additional file 4: of JNKi- and DAC-programmed mesenchymal stem/stromal cells from hESCs facilitate hematopoiesis and alleviate hind limb ischemia
Creators: name: Wei, Yimeng
name: Hou, Huixing
name: Zhang, Leisheng
name: Zhao, Nianhuan
name: Li, Chengwen
name: Huo, Jiali
name: Liu, Ying
name: Zhang, Wenxia
name: Li, Zongjin
name: Liu, Dengke
name: Han, Zhibo
name: Zhang, Lei
name: Song, Baoquan
name: Chi, Ying
name: Han, Zhongchao
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Developmental Biology
subject: Hematology
subject: Computational Biology

description: Figure S4. Identification of hematopoietic-supporting effect of hESC-MSCs. (PDF 232 kb)
Synthesis, Characterization and Molecular Docking of New Nucleosides and Schiff Bases Derived from Ampyrone as Antiviral Agents to Contain the COVID-19 Virus
Creators: name: Alotaibi, Saad H.
name: Amer, Hamada H.
name: Touil, Nadia
name: Abdel-Moneim, Ahmed S.
name: Soliman, Mohamed M.
name: Zaki, Yasser H.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: A new series of nucleoside derivatives was prepared from the reaction of 4-aminoantipyrene with different sugar moieties. In addition, ampyrone’s reaction with different aromatic aldehydes gave the corresponding Schiff base derivatives, which were also synthesized. Both molecular docking and in vitro antiviral activities at different concentrations of different synthesized compounds against SARS-CoV-2 were screened. All newly synthesized compounds were characterized on the basis of IR, 1H NMR and 13C NMR spectral data and physical data. The compounds were screened for potential cytotoxic activities. The molecular docking analysis showed that compounds 6b, 6e, 6c, 6f and 6d exhibited relatively higher binding energies (−8.1, −8.1, −8.3, −8.4 and −8.7 kcal/mol, respectively) compared to all the other compounds. However, the different compounds did not show any promising in vitro antiviral activities against SARS-CoV-2.
O silêncio como teatro – aproximações à produção dramática de António Torrado
Creators: name: Ramos, Ana Margarida
Publisher: name: Forma Breve
Year: 2007

description: É objectivo deste estudo proceder à caracterização da produção dramática de António Torrado a partir da noção de teatro mínimo. Assim, serão alvo de análise alguns dos seus textos mais breves destinados ao público infantil, os textos para teatro radiofónico e ainda uma colectânea de textos dramáticos, O Teatro do Silêncio, cuja contenção ao nível da linguagem verbal utilizada em palco permite lê-la enquanto exemplo de forma mínima.
description: Forma Breve, n.º 5 (2007): Teatro mínimo
title: Study on the Evolution of the Relationship Between Urban Housing Space and Topography in Chongqing’s Mountainous Old-town Riverfront in China’s Reform Era: An Environmental History’s Perspective
Creators: name: Chen, Liran
Publisher: name: Conference Proceedings  XXIX International Seminar on Urban Form ISUF 2022 Urban Redevelopment and Revitalisation A Multidisciplinary Perspective/ Lodz University of Technology Press
Year: 2023
Subjects: Vernacular Housing, Topography, Environmental History.

description: Before China’s post-1978 reform era, the riverfront slopes of mountainous cities in Chongqing accommodated vernacular housing landscape intertwined with mountain-water topography. During the reform, such relationship between housing and topography changed drastically. This research investigates the changing relationship between housing space and topography in Chongqing in the reform era. Environmental history investigates the history of human-nature interactions, applying social division analysis to study how different groups developed their relations when occupying natural resources, and cultural construction analysis to study how humans developed their understandings about nature. This research applies environmental history’s research framework. In the 1980s, notwithstanding the introduction of modern high-rise housing to Chongqing, the city’s riverfront housing form and local residents’ daily life adapted to topography sensitively, which was similar to the pre-1978 period. In the 1990s, intense riverfront high-rise housing development flattened riverfront slopes and seduced wealthy groups to replace local residents to live in riverfront housing with river view, interpreted by the mass as Chongqing’s loss of its mountain-water urban feature. After the late 1990s, Chongqing government started preserving the remaining riverfront vernacular housing, but driven by commercial motives, such preservation produced commercial areas themed with “traditional mountain-water cityscape” and relocated local residents, detaching topography from local residents’ daily life. The changing relationship between housing and topography signified that Chongqing’s riverfront mountainous cityscape making shifted from the mass-oriented to the elite-oriented, from serving the mass’ daily needs to serving the elite’s interests/visions, due to the fact that the urban elites were not fully aware of the significance of the housing landscape in which the mass’ daily dwelling intertwined with topography for Chongqing city’s long-term development, and that there was a lack of a mechanism supporting the preservation of such housing landscape during urban renewal.
Long-time asymptotics for polymerization models
Creators: name: Calvo, Juan
name: Doumic, Marie
name: Perthame, Benoît
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: This study is devoted to the long-term behavior of nucleation, growth and fragmentation equations, modeling the spontaneous formation and kinetics of large polymers in a spatially homogeneous and closed environment. Such models are, for instance, commonly used in the biophysical community in order to model in vitro experiments of fibrillation. We investigate the interplay between four processes: nucleation, polymeriza-tion, depolymerization and fragmentation. We first revisit the well-known Lifshitz-Slyozov model, which takes into account only polymerization and depolymerization, and we show that, when nucleation is included, the system goes to a trivial equilibrium: all polymers fragmentize, going back to very small polymers. Taking into account only polymerization and fragmentation, modeled by the classical growth-fragmentation equation, also leads the system to the same trivial equilibrium, whether or not nucleation is considered. However, also taking into account a depolymer-ization reaction term may surprisingly stabilize the system, since a steady size-distribution of polymers may then emerge, as soon as polymeriza-tion dominates depolymerization for large sizes whereas depolymerization dominates polymerization for smaller ones-a case which fits the classical assumptions for the Lifshitz-Slyozov equations, but complemented with fragmentation so that " Ostwald ripening " does not happen.
description: https://link.springer.com/article/10.1007/s00220-018-3218-5
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0399
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0399, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0399, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Bidirectional Intimate Partner Violence Among Military Service Members and Veterans: A Scoping Review
Creators: name: Yeterian, Julie
name: Portnoy, Galina
name: Relyea, Mark
name: Demoss, Lauren
name: Stover, Carla
name: Coppola, Elizabeth
name: Brandt, Cynthia
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Social and Behavioral Sciences
subject: bidirectional intimate partner violence
subject: intimate partner violence
subject: military service members
subject: veterans

description: This preregistration is for a scoping review on bidirectional intimate partner violence (IPV) among military service members and veterans.
O poliedro da linguagem: as difrações imagéticas em «a pedra que não caiu»
Creators: name: Vitagliano, Karina Marize
Publisher: name: Forma Breve
Year: 2007

description: A escrita de Maria Gabriela Llansol desestabiliza as estruturas fi xas dos gêneros literários, promovendo um intenso diálogo entre eles. No conto «A pedra que não caiu» (Os pregos na erva, 1962) identifi ca-se um enredo desprovido de ações em contraposição a uma estrutura que exalta os sons e explora as potencialidades do texto por meio das «cenas fulgor» (expressão da autora). Há, portanto, um deslocamento da narratividade para a textualidade que nos convida a encarar a pedra-palavra como um poliedro capaz de difratar inúmeras imagens.
description: Forma Breve, n.º 5 (2007): Teatro mínimo
Assessments of preprocessing methods for Landsat time series images of mountainous forests in the tropics
Creators: name: Katsuto Shimizu
name: Ota, Tetsuji
name: Nobuya Mizoue
name: Shigejiro Yoshida
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Monitoring forest changes based on numerous satellite images has been recently conducted in the tropics. Preparation of a time series of satellite images, sometimes referred to as preprocessing, is essential for conducting robust detection of forest change. To create consistent and stable conditions in satellite images, the best methods have to be used in each step to correct various sources of noise. This study assessed three atmospheric correction methods, six topographic correction methods, and eight gap-filling methods to produce the best possible time series of Landsat images of tropical seasonal forests. The results showed that the best methods for atmospheric and topographic correction were relative corrections using a Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS), which is based on a 6S radiative transfer model, and the C-correction, respectively. Weighted linear regression and multiple linear regression models were selected as the best models for the filling of data gaps associated with Scan Line Corrector-off and clouds, respectively. This study provided the best possible image preprocessing for trajectory-based change detection using annual Landsat images. Although the best possible preprocessing methods might vary depending on the change detection methods used in different study areas, the results highlight the preferable preprocessing methods, even for different types of time series analysis.
A imagem no poema «A flor que ainda não nasceu na página», de António Ramos Rosa
Creators: name: Hoffmann, Rachel
Publisher: name: Forma Breve
Year: 2007

description: Esse trabalho pretende analisar o poema «A fl or que ainda não nasceu na página» de António Ramos Rosa a partir da observação da discussão que ele realiza sobre o próprio fazer poético. Desse modo, para realizarmos nossa interpretação, partimos de um levantamento de seus procedimentos formais, principalmente no que se refere a repetição e reformulação do signo «fl or», como um objeto artístico que se realiza e se desvenda durante o processo da leitura. Acreditamos que o debate sobre a natureza da linguagem literária proposto pelo poema de Rosa recoloca esse objeto como um espaço para a vacilação dos mais diversos discursos bem como de nossa relação com a palavra e com o mundo. Para lermos o poema dessa maneira, nos apoiamos principalmente nas observações de Chklovski (1973), Barthes (1978), Bosi (1977) e Paz (1982).
description: Forma Breve, n.º 5 (2007): Teatro mínimo
Testing the anisotropy of the Universe with the distance duality relation
Creators: name: Li, Xin
name: Tang, Li
name: Lin, Hai-Nan
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The distance duality relation (DDR) is valid in Riemannian spacetime. The astronomical data hint that the universe may have certain preferred direction. If the universe is described by anisotropic cosmological models based on Riemannian spacetime, then DDR still valid. If the anisotropy universe is described by other models which are not based on Riemannian spacetime, then DDR is violated. Thus, DDR could be used to test the validity of these anisotropic cosmological models. In this paper, we perform anisotropic DDR parametrization with the dipolar structures. The DDR is tested by comparing the luminosity distance from type-Ia supernovae (Union 2.1 and JLA compilations) and the angular diameter distance from strong gravitational lensing (SL) systems at the same redshift. It is shown that, the DDR is valid with the Union2.1 compilation, while is violated more than 1$σ$ confidence level with the JLA compilation. Additionally, we verify the statistical signification of our method with Monte Carlo simulations. Due to the large uncertainty of available data, no strong evidence is found to violate the DDR in the anisotropic models.
description: 10 pages,2 tables
Kinematics, activity and youth in the CARMENES input catalogue of M dwarfs
Creators: name: José A. Caballero
name: David Montes Gutiérrez
name: Carlos Cardona Guillén
name: Víctor J. S. Béjar
name: Hugo M. Tabernero
name: María R. Zapatero-Osorio
name: Perdo J. Amado
name: Sandra V. Jeffers
name: Marina Lafarga
name: Nicolas Lodieu
name: Andreas Quirrenbach
name: Ansgar Reiners
name: Ignasi Ribas
name: Patrick Schöfer
name: Andreas Schweitzer
name: Walter Seifert
Publisher: name: Zenodo
Year: 2024
Subjects: late-type stars
low mass stars
stellar kinematics
solar neighbourhood

description: We use the public code SteParKin to derive their galactic space velocities, which served us to locate them into the different galactic populations. We also identify candidate members in young stellar kinematic groups with SteParKin, LACEwING, and BANYAN Sigma based on their kinematics. From the combination of kinematic assignments as a proxy of age and rotation-activity features, we define five rotation-activity-spectral type relations that M dwarfs under 800 Ma satisfy. We are then able to assess youth in this regime from the available data. We identify around 170 young (age<800 Ma) M dwarfs in the solar neighbourhood, many of which have never been suggested before as young candidate stars. We also provide a list with 50 active M dwarfs and with the strongest surface magnetic fields among which there are 7 M dwarfs that are perhaps the youngest, most active, nearest M dwarfs observable from Calar Alto, with ages less than about 50 Ma.
Bibliometric analysis of production planning and control (1990–2016)
Creators: name: Adeel Akmal
name: Podgorodnichenko, Nataliya
name: Greatbanks, Richard
name: Everett, André M.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: Molecular Biology
Developmental Biology
Science Policy

description: Production Planning and Control (PPC) has been one of the primary publishing outlets for operations management research for nearly three decades. This paper presents bibliometric analysis of the journal from its inception through 2016. PPC was analysed from six different perspectives to provide reliable and in-depth information about the journal’s performance and development. The analysis considered the development of the journal itself, the countries of contributing authors, authors’ academic and practitioner organisation affiliations, the top publishing and most cited authors, the most cited articles, and finally the topics of published papers through analysis of titles, keywords and abstracts. It was found that the journal is considered an outlet for both practice and academic research, reflecting changes over time in the landscape of operations management.
Synthesis of N-Methylspiropyrrolidine Hybrids for Their Structural Characterization, Biological and Molecular Docking Studies
Creators: name: Asad, Mohammad
name: Arshad, Muhammad Nadeem
name: Asiri, Abdullah M.
name: T.N., Mohammed Musthafa
name: Khan, Salman A.
name: Rehan, Mohd
name: Oves, Mohammad
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: A set of novel N-methylspiropyrrolidine hybrids have been synthesized regio selectively employing 1,3-dipolar cycloaddition reaction of substituted chalcones with azomethine ylides (work up in situ from isatin and sarcosine). The spiropyrrolidines structures were studied using FT-IR, 1H and 13C NMR spectroscopic data, and was finally confirmed by X-ray diffraction study. Hirshfeld surface analysis was correlated with X-ray diffraction and described different intermolecular contacts. Good antibacterial activity was reported against gram-positive and gram-negative bacterial strains of Bacillus subtillis, Enterococcus faecalis, E. coli, and Pseudomonas aeruginosa. Initially, antibacterial activity of compounds was confirmed by the zone of inhibition. Most of the compounds have shown MIC and MBC in the range between 50-200 µg∕mL against both types of bacteria. Further, for mechanism of action, the tested compounds were checked for the inhibition of an established bacterial drug target, DNA gyrase using in silico approaches.
A escrita como magnífica impostura
Creators: name: Santos, Cristina Firmino
Publisher: name: Forma Breve
Year: 2007

description: O propósito deste ensaio é reflectir, tomando como objecto de análise o conto de J.L. Borges «Emma Zunz», sobre a aprendizagem literária como acto de reescrita e de insubordinação mimética que encontra o seu correlato na infâmia.
description: Forma Breve, n.º 5 (2007): Teatro mínimo
Ground state cooling in a hybrid optomechanical system with a three-level atomic ensemble
Creators: name: Li, Tan
name: Zhang, Shuo
name: Huang, He-Liang
name: Li, Feng-Guang
name: Fu, Xiang-Qun
name: Wang, Xiang
name: Bao, Wan-Su
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Cooling mechanical resonators is of great importance for both fundamental study and applied science. We investigate the hybrid optomechanical cooling with a three-level atomic ensemble fixed in a strong excited optical cavity. By using the quantum noise approach, we find the upper bound of the noise spectrum and further present three optimal parameter conditions, which can yield a small heating coefficient, a large cooling coefficient, and thus a small final phonon number. Moreover, through the covariance matrix approach, results of numerical simulation are obtained, which are consistent with the theoretical expectations. It is demonstrated that our scheme can achieve ground state cooling in the highly unresolved sideband regime, within the current experimental technologies. Compared with the previous cooling methods, in our scheme, there are fewer constraints on the drive strength of atomic ensemble and number of atoms in the ensemble. In addition, the tolerable ranges of parameters for ground state cooling are extended. As a result, our scheme is very suitable for experiments and can be a guideline for the research of hybrid optomechanical cooling.
description: 21 pages, 7 figures. Comments Welcome!
«A quantas gentes vês porás o freio»: o outro n’Os Lusíadas
Creators: name: Boechat, Virgínia Bazzetti
Publisher: name: Forma Breve
Year: 2007

description: O presente ensaio propõe-se a observar n’Os Lusíadas o conjunto de informações acerca de povos não-europeus e não-cristãos – africanos, indianos e muçulmanos – no intuito de compreender as características e contradições apresentadas em tais imagens. Busca também estabelecer relações entre estas imagens e os interesses e a identidade portuguesa naquele tempo de nascimento do conceito de humanidade.
description: Forma Breve, n.º 5 (2007): Teatro mínimo
Noether-Wald energy in Critical Gravity
Creators: name: Anastasiou, Giorgos
name: Olea, Rodrigo
name: Rivera-Betancour, David
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Criticality represents a specific point in the parameter space of a higher-derivative gravity theory, where the linearized field equations become degenerate. In 4D Critical Gravity, the Lagrangian contains a Weyl-squared term, which does not modify the asymptotic form of the curvature. The Weyl$^{2}$ coupling is chosen such that it eliminates the massive scalar mode and it renders the massive spin-2 mode massless. In doing so, the theory turns consistent around the critical point. Here, we employ the Noether-Wald method to derive the conserved quantities for the action of Critical Gravity. It is manifest from this energy definition that, at the critical point, the mass is identically zero for Einstein spacetimes, what is a defining property of the theory. As the entropy is obtained from the Noether-Wald charges at the horizon, it is evident that it also vanishes for any Einstein black hole.
description: 7 pages, no figures, Final version for PLB
Electronic structure and glass forming ability in early and late transition metal alloys
Creators: name: Babić, E.
name: Ristić, R.
name: Figueroa, I. A.
name: Pajić, D.
name: Skoko, Ž.
name: Zadro, K.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A correlation between the change in magnetic susceptibility (Δ\c{hi}exp) upon crystallization of Cu-Zr, Hf metallic glasses (MG) with their glass forming ability (GFA) observed recently is found to apply to Cu-Ti and Zr-Ni alloys, too. In particular, a small Δ\c{hi}exp , which reflects similar electronic structures, ES, of glassy and corresponding crystalline alloys, corresponds to high GFA. Here, we studied Δ\c{hi}exp in five Cu-Ti and four Cu-Zr and Ni-Zr MGs. The fully crystalline final state of all alloys was verified from X-ray diffraction patterns. The variation of GFA with composition in Cu-Ti, Cu-Zr and Cu-Hf MGs was established from the variation of the corresponding critical casting thickness, dc. Due to the absence of data for dc in Ni-Zr MGs their GFA was described by using empirical criteria, such as the reduced glass transition temperature. A very good correlation between Δ\c{hi}exp and dc (and/or other criteria for GFA) was observed for all alloys studied. The correlation between the ES and GFA showed up best for Cu-Zr and NiZr2 alloys where direct data for the change in ES (ΔES) upon crystallization are available. The applicability of the Δ\c{hi}exp (ΔES) criterion for high GFA (which provides a simple way to select the compositions with high GFA) to other metal-metal MGs (including ternary and multicomponent bulk MGs) is briefly discussed.
description: 29 pages, 6 figures
Copper(II)-dipicolinate-mediated clickable azide–alkyne cycloaddition in water as solvent
Creators: name: Lahoucine Bahsis
name: Ayouchia, Hicham Ben El
name: Anane, Hafid
name: Triki, Smail
name: Julve, Miguel
name: Salah-Eddine Stiriba
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: Copper(II)-dipicolinate complex [CuII(dipic)(H2O)2] (1) (H2L = dipicolinic acid (H2dipic)) was synthesized via oxidation of copper(I) iodide and pyridine-2,6-dicarboxylic acid in water and acetonitrile in the presence of glycine. Complex 1 was characterized by FT-IR and elemental analysis and its structure confirmed by single crystal X-ray analysis. This complex is an efficient precatalyst that mediates azide–alkyne cycloaddition reactions in water at room temperature either in the absence or presence of a reducing agent. Compound 1-mediated azide–alkyne cycloaddition affords alkyl/aryl substituted 1,2,3-triazole heterocycles in a regioselective manner and excellent yields under very mild reaction conditions matching the criteria of greener protocols.
Additional file 1: of Relationship between the respiratory microbiome and the severity of airflow limitation, history of exacerbations and circulating eosinophils in COPD patients
Creators: name: Millares, Laura
name: Pascual, Sergi
name: Montón, Concepción
name: García-Núñez, Marian
name: Lalmolda, Cristina
name: Faner, Rosa
name: Casadevall, Carme
name: Setó, Laia
name: Capilla, Silvia
name: Moreno, Amàlia
name: Castro-Acosta, Ady Angélica
name: Alvarez-Martinez, Carlos
name: Sibila, Oriol
name: Peces-Barba, Germán
name: Cosio, Borja
name: Agustí, Alvar
name: Gea, Joaquim
name: Monsó, Eduard
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S1. Relative abundances of the phyla detected. Figure S1. The TM7 phylum had significantly lower relative abundance in patients with one exacerbation than patients without exacerbations the previous year (dotted line = median). Figure S2. Thirteen genera with significantly lower relative abundances in COPD patients with one exacerbation the previous year compared to non-exacerbators. Figure S3. A significant reduction in the RA of phyla TM7 and Spirochaetes in patients with ≥2 exacerbations the previous year, using patients without exacerbations as the reference (dotted line = median). Figure S4. Phyla with significantly higher relative abundances in COPD patients showing circulating eosinophils ≥2%. (DOCX 725 kb)
Copper(II)-dipicolinate-mediated clickable azide-alkyne cycloaddition in water as solvent
Creators: name: Lahoucine Bahsis
name: Ayouchia, Hicham Ben El
name: Anane, Hafid
name: Triki, Smail
name: Julve, Miguel
name: Salah-Eddine Stiriba
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: Copper(II)-dipicolinate complex [CuIIL(H2O)2] (1) (H2L = dipicolinic acid (H2dipic)) was synthesized via oxidation of copper(I) iodide and pyridine-2,6-dicarboxylic acid in water and acetonitrile in the presence of glycine. Complex 1 was characterized by FT-IR and elemental analysis and its structure confirmed by single crystal X-ray analysis. This complex is an efficient precatalyst that mediates azide-alkyne cycloaddition reactions in water at room temperature either in the absence or presence of a reducing agent. Compound 1-mediated azide-alkyne cycloaddition affords alkyl/aryl substituted 1,2,3-triazole heterocycles in a regioselective manner and excellent yields under very mild reaction conditions matching the criteria of greener protocols.
Crystal structures, DNA-binding ability and influence on cellular viability of gold(I) complexes of thiosemicarbazones
Creators: name: Almeida, Carolane M.
name: Nascimento, Gabriel P.
name: Magalhães, Kelly G.
name: Iglesias, Bernardo A.
name: Gatto, Claudia C.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology

description: The present study reports the synthesis and crystal structure of four novel gold(I) complexes with di-2-pyridyl ketone N(4)-ethylthiosemicarbazone (L1) and 2-acetylfuran-4-methyl-3-thiosemicarbazone (L2). All the gold(I) complexes were observed with monodentate thiosemicarbazones and exhibited gold(I) ions with linear geometries, bound to a sulfur atom of the ligand and a halogen ion (Br− or Cl−). The crystal structures of gold complexes with Br− and thiosemicarbazone are the first examples reported. Interestingly, 2[AuBr(HL1)]2Br was observed to have a Au⋯Au length of 3.155(8) Å, and this distance suggests an unusual Au⋯Au interaction in the solid state. The ability of the thiosemicarbazones and the corresponding gold(I) complexes to bind to DNA was studied by UV-vis and emission spectroscopy. The effect on cell viability of the compounds was evaluated against human breast cancer cell lines. The results show that the gold(I) complexes exhibit more potent inhibition of tumor growth than the free ligands.
Energy momentum tensor for translation invariant renormalizable noncommutative field theory
Creators: name: Baloitcha, Ezinvi
name: Lahoche, Vincent
name: Samary, Dine Ousmane
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we derive the energy momentum tensor for the translation invariant noncommutative Tanasa scalar field model. The Wilson regularization procedure is used to improve this tensor and the local conservation property is recovered. The same question is addressed in the case where the Moyal star product is deformed including the tetrad fields. It provides with an extension of the recent work [J. Phys. A: Math. Theor. 43 (2010) 155202], regarding the computation and properties of the Noether currents to the renormalizable models.
description: 12 pages
A escrita em metamorfose: uma leitura das Tisanas
Creators: name: Teixeira, Claudio Alexandre Barros
Publisher: name: Forma Breve
Year: 2007

description: Tisanas é um conjunto de poemas em prosa de Ana Hatherly que mesclam diferentes formas narrativas, como a fábula, a parábola, o verbete de enciclopédia, numa escrita híbrida e paródica, sem uma seqüência linear. Os temas são organizados em seqüências assimétricas, assistemáticas, com cruzamentos, variantes e interpolações temáticas.
description: Forma Breve, n.º 5 (2007): Teatro mínimo
SchNet: A continuous-filter convolutional neural network for modeling quantum interactions
Creators: name: Schütt, Kristof T.
name: Kindermans, Pieter-Jan
name: Sauceda, Huziel E.
name: Chmiela, Stefan
name: Tkatchenko, Alexandre
name: Müller, Klaus-Robert
Publisher: name: arXiv
Year: 2017
Subjects: subject: Machine Learning (stat.ML)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Deep learning has the potential to revolutionize quantum chemistry as it is ideally suited to learn representations for structured data and speed up the exploration of chemical space. While convolutional neural networks have proven to be the first choice for images, audio and video data, the atoms in molecules are not restricted to a grid. Instead, their precise locations contain essential physical information, that would get lost if discretized. Thus, we propose to use continuous-filter convolutional layers to be able to model local correlations without requiring the data to lie on a grid. We apply those layers in SchNet: a novel deep learning architecture modeling quantum interactions in molecules. We obtain a joint model for the total energy and interatomic forces that follows fundamental quantum-chemical principles. This includes rotationally invariant energy predictions and a smooth, differentiable potential energy surface. Our architecture achieves state-of-the-art performance for benchmarks of equilibrium molecules and molecular dynamics trajectories. Finally, we introduce a more challenging benchmark with chemical and structural variations that suggests the path for further work.
التفكير المنظومي
Creators: name: زكريا،محمود شريف احمد
Publisher: name: Zenodo
Year: 2022
Subjects: التفكير المنظومي،التفكير التقليدي،التفكير التحليلي،التفكير التركيبي

description: تبحث الدراسة الحالية في كيفية توظيف أحد المداخل المرتبطة بعلم النفس المعرفـي، في محاولة لفهم بعض القضايا المتعلقة بتخصص المكتبات والمعلومات، ألا وهـو: المـدخل المنظومي في التفكير أو التفكير المنظومي؛ إذ يصلح هذا المدخل- في ضوء نتائج الدراسـة الحالية وما أفضت إليه نتائج الدراسات السابقة وأدب الموضوع لأن يستعان بـه فـي فهـم بعض القضايا أو المشكلات أو الظواهر العلمية المرتبطة بتخصص المكتبـات والمعلومـات، على نحو أفضل وأكثر تكاملاً وأوضح تعبيراً ودلالة. وقد عنـي الباحـث بقـراءة مجموعـة متفرقة من تلك القضايا والمشكلات؛ سيما: ما يتعلق بـإدارة مؤسسـات المعلومـات، وإدارة الأزمات والكوارث بتلك المؤسسات، وظاهرة الاتصال العلمـي ومـا تنضـوي عليـه مـن ارتباطات، وتدريس برامج المكتبات والمعلومات، باعتبار أن كلاً من تلك المباحــث وغيرهـا إنما تعد بدورها منظومة، حيث تتكون من مجموعة من العناصر المتناغمة معاً، والتي لها مـا تتأثر به وتؤثر فيه، وبحيث يظر إلى كل عنصر منها بصـورة شـاملة، لا بصـورة فرديـة متجردة من أية دلالة أو علاقة أو ارتباط بغيرها. وعلى هذا، هدفت الدراسة الحالية إلى تقـديم رؤية تنظيرية فلسفية مستقاة من علم النفس المعرفي ونظريـة المعرفـة، ومصـاغة برؤيـة تخصصية خالصة، وذلك من أجل التعرف على احتمالات توظيف هذا المدخل المعرفـي فـي فهم مختلف المحاور البحثية التخصصية في مجال المكتبات والمعلومات
Growth of thin films of single-chain magnets on functionalized silicon surfaces
Creators: name: M. Castellano
name: J. Ferrando-Soria
name: N. Moliner
name: J. Cano
name: M. Julve
name: F. Lloret
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology

description: A one-pot strategy for the direct growth of continuous and regular thin films of a neutral oxamato-bridged heterobimetallic chain, synthesized from Co2+ nitrate and the tetramethylammonium salt of the anionic copper(II) complex (Me4N)2[Cu(2,6-Et2pa)2]·6H2O (1) (2,6-Etpa = N-2,6-diethylphenyloxamate) over Si(111) surfaces functionalized with carboxylic acid terminating groups has been developed. Variation of the growth conditions can provide important differences in the morphology of the obtained films when working in H2O at 20 °C. An anisotropic growth of 1-D fibers is observed under stoichiometric conditions (Co2+/1 = 1:1), while an isotropic growth of 3-D particles occurs for an excess of Co2+, as demonstrated by AFM. The dc magnetic measurements performed over the fiber- (3d) or particle-based films (3e) show a characteristic behavior of a 1-D ferrimagnetic chain compound. They are comparable to the ones of the bulk material of formula [CoCu(2,6-Et2pa)2(H2O)2] (2) prepared in H2O at 20 °C which possesses slow magnetic relaxation effects typical of a SCM.
Aspectos da modernidade em El Arco y la Lira, de Octavio Paz
Creators: name: Bueno, Danilo Rodrigues
Publisher: name: Forma Breve
Year: 2007

description: Este estudo propõe-se a indicar aspectos de Modernidade constantes do livro El Arco y La Lira, de Octavio Paz, sob a hipótese hermenêutica de que há uma dialética imanente entre as suas obras crítica e poética, elemento caracterizador da consciência crítica da poesia moderna.
description: Forma Breve, n.º 5 (2007): Teatro mínimo
HH e YHWH: Hilda Hilst e o deus javista
Creators: name: Amorim, Bernardo Nascimento
Publisher: name: Forma Breve
Year: 2007

description: Neste pequeno artigo, tento aproximar a poesia de Hilda Hilst da Bíblia hebraica, tendo como eixo de análise, em uma perspectiva comparatista, a observação sobre duas figuras: a do deus da Tanach e a de uma alteridade muito particular presente nos poemas de Hilst.
description: Forma Breve, n.º 5 (2007): Teatro mínimo