cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Intensive care nurses' perceptions of brain death
Creators: name: White, Geoff
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Cyclist and pedestrian trust in automated vehicles: An on-road and simulator trial
Creators: name: Parkin, John
name: Crawford, Fiona
name: Flower, Jonathan
name: Alford, Chris
name: Morgan, Phillip
name: Parkhurst, Graham
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 111714
subject: Mental Health

description: Automated vehicles (AVs) need to be trusted by cyclists and pedestrians where they will share the road. To test trust, cyclists and pedestrians, and a comparison cohort of drivers, observed trials of both a road and simulator AV undertaking three common priority-based maneuvers: a right turn into a side road, overtaking a parked car, and passing over a pedestrian priority (zebra) crossing. The AV made the maneuvers either giving way, or not giving way, to a pedestrian or cyclist. One hundred and thirty-four participants aged 18 to 79 years were recruited based on being predominantly either a pedestrian, cyclist, or driver in their regular road use. For the on-road trials, the cyclist and pedestrian participants observed the AV maneuvers from the adjacent footway, and the driver participants observed from inside the AV. In the simulation environment, all participants were inside the automated vehicle. Trust scores were higher when participants observed a maneuver where the AV had to give way to a cyclist, and this can be linked with the re-assurance provided by the behavior of the AV in such an encounter. There was no significant difference in trust by road user type (cyclist, pedestrian or driver), age or driving experience, suggesting messaging to road users about the impacts of automated vehicles need not be differentiated by road user type. There was some evidence of differences in trust, especially for more complex maneuvers, between the on-road trial and the simulator, suggesting a need for caution in reliance on simulation-only experiments.
Pressure effect on superconductivity in FeSe0.5Te0.5
Creators: name: Shylin, Sergii I.
name: Ksenofontov, Vadim
name: Naumov, Pavel G.
name: Medvedev, Sergey A.
name: Tsurkan, Vladimir
name: Deisenhofer, Joachim
name: Loidl, Alois
name: Schoop, Leslie M.
name: Palasyuk, Taras
name: Wortmann, Gerhard
name: Felser, Claudia
Publisher: name: arXiv
Year: 2016
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Due to the simple layered structure, isostructural FeSe and FeSe0.5Te0.5 are clue compounds for understanding the principal mechanisms of superconductivity in the family of Fe-based superconductors. High-pressure magnetic, structural and Mössbauer studies have been performed on single-crystalline samples of superconducting FeSe0.5Te0.5 with Tc = 13.5 K. Susceptibility data have revealed a strong increase of Tc up to 19.5 K for pressures up to 1.3 GPa, followed by a plateau in the Tc(p) dependence up to 5.0 GPa. Further pressure increase leads to a disappearance of the superconducting state around 7.0 GPa. X-ray diffraction and Mössbauer studies explain this fact by a tetragonal-to-hexagonal structural phase transition. Mössbauer parameters of the non-superconducting high-pressure phase indicate less covalency of Fe-Se bonds. Based on structural and susceptibility data we conclude about a common character of Tc(p) diagrams for both FeSe and FeSe0.5Te0.5 superconductors.
description: 7 pages, 8 figures, published in Phys. Status Solidi B
The social and discursive construction of boys' experience of their schooling
Creators: name: Whelen, John Donald
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field. Winner of the Mollie Holman Doctoral Medal for Excellence
Charge transfer at hybrid inorganic-organic interfaces
Creators: name: Wang, Xiaoming
name: Esfarjani, Keivan
name: Zebarjadi, Mona
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Organic dopants are frequently used to surface-dope inorganic semiconductors. The resulted hybrid inorganic-organic materials have a crucial role in advanced functional materials and semiconductor devices. In this article, we study charge transfer at hybrid silicon-molecule interfaces theoretically. The idea is to filter out the best molecular acceptors to dope silicon with hole densities as high as 1013 cm-2. Here, we use a combinatorial algorithm merging chemical hardness method and first-principles DFT and GW calculations. We start by using the chemical hardness method which is simple and fast to narrow down our search for molecular dopants. Then, for the most optimistic candidates, we perform first-principles DFT calculations and discuss the necessity of GW corrections. This screening approach is quite general and applicable to other hybrid interfaces.
Some New Evidence on the Relationship Between School Provision and Parental Labor Supply
Creators: name: Ward, Jason Michael
Publisher: name: University of Illinois at Chicago
Year: 2019
Subjects: Uncategorized

description: This work provides new evidence on the strength of the relationship between school provision for children and parental labor supply. This link is explored using two distinct sources of variation in school provision, the four-day school week (4DW), and the annual summer break. Chapter 1 assesses the effect of the 4DW on parental labor supply and other measures of household welfare. Difference-in-differences results indicate that married mothers of all grade-school-aged children reduce employment and hours worked in an economic and statistically significant manner in response to the 4DW. Both married fathers and single mothers do not reduce employment and reduce their hours worked in only a marginally significant manner. Chapter 2 describes a meaningful decline in both employment and presence at work among married mothers of grade-school-aged children across the months of the summer break. Single mothers reduce their summer labor supply less and I observe some responsiveness among married fathers in presence at work over the summer. The role of this decline in summer labor supply on the gender gap in experience and earnings, as well as household time use and child cognitive and non-cognitive skills are also explored.
MORTE SÚBITA NEONATAL: Análise de conceito mediante protocolo de escopo
Creators: name: ROCHA, ROSSANA MARIA DA SILVA
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Medicine and Health Sciences
subject: Morte Súbita infantil

description: Este estudo é considerado uma Revisão de Escopo, que tem a utilidade de mapear os conceitos-chaves que sustentam um campo de pesquisa e esclarece as definições de trabalho e/ou os limites conceituais de um tópico, baseado na metodologia do Joana Briggs Instituto e no PRISMA ScR (Tricco).
The value of genuine partnership and reciprocity: a comparison of incremental vs. transformational innovation
Creators: name: Meenken, Esther
name: Warbrick, Lisa
name: Stevens, David
name: Wheeler, David
name: Pletnyakov, Peter
name: Zydenbos, Sue
Publisher: name: AgResearch
Year: 2023
Subjects: Agro-ecosystem function and prediction

description: Work in partnership between New Zealand Bioeconomy in the Digital Age (NZBIDA) and Te Pu Oranga Whenua (TPOW)
Influences of Major Depression and Posttraumatic Stress Disorder on Trauma and Alcohol Cue Reactivity
Creators: name: Hanaan Bing-Canar
Publisher: name: University of Illinois at Chicago
Year: 2019
Subjects: Uncategorized

description: Despite established support for the development of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) comorbidity by way of self-medication alcohol use, models of PTSD-AUD etiology rarely account for the role of other common comorbidities in risk processes, namely major depressive disorder (MDD). Past studies indicate that approximately 50.0% of individuals with PTSD and 40.3% of individuals with AUD meet criteria for current MDD. Importantly, MDD may interact with PTSD to influence AUD risk by enhancing incentive for self-medication and/or by increasing motivation for alcohol-related reward. Laboratory models of trauma and alcohol cue reactivity are well suited to evaluate how depression and PTSD may work together on risk for AUD. The trauma and alcohol cue reactivity paradigm assesses craving in response to four combinations of narrative (trauma vs. neutral) and beverage (alcohol vs. water) cues. The current study examined the main and interactive effects of PTSD (Clinician Administered PTSD scale for DSM-5; CAPS) and depression symptoms (Center for Epidemiologic Studies Depression Scale-Revised; CESD-R) on trauma and alcohol cue reactivity. Forward-fitted linear mixed effects models with deviance testing were conducted to ascertain the impact of the within-subjects factors (narrative cue and beverage cue) and covariates (PTSD symptoms and depressive symptoms) on self-reported and physiological (salivation, in grams) alcohol craving after controlling for cumulative trauma exposure. For craving, there was a main effect of total depressive symptoms on self-reported craving, after accounting for the interaction between PTSD symptoms and narrative cue, B = 0.418, p = .028, and improved model fit above an initial base model, X2 = 4.74, p < .05. However, total depressive symptoms did not significantly interact with narrative or beverage cues to predict craving, p’s > .05. Further, depression did not exhibit main or interactive effects on salivation, p’s > .05. These results suggest that depressive symptoms may increase subjective craving for alcohol, regardless of trauma or alcohol contextual cues. Further research is needed to explain the role of MDD in PTSD-AUD etiology and maintenance.
The marginalisation of theoretical knowledge in vocational qualifications in Australia : a blended Bernsteinian & critical realist analysis
Creators: name: Wheelahan, Elizabeth Mary
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Inverse source problem for time fractional diffusion with discrete random noise
Creators: name: Huy, Tuan Nguyen
name: Nane, Erkan
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 60K40

description: In this paper, we deal with the inverse source problem of determining a source in a time fractional diffusion equation where data are given at a fixed time. This problem is ill-posed, i.e., the solution does not depend continuously on the data. To regularize the instable solution, we use the trigonometric method in nonparametric regression associated with the truncated expansion method. We also investigate the convergence rate.
description: 12 Pages, submitted for publication
A transportable optical lattice clock with $7\times10^{-17}$ uncertainty
Creators: name: Koller, S. B.
name: Grotti, J.
name: Vogt, St.
name: Al-Masoudi, A.
name: Dörscher, S.
name: Häfner, S.
name: Sterr, U.
name: Lisdat, Ch.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optics (physics.optics)
subject: Atomic Physics (physics.atom-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a transportable optical clock (TOC) with $^{87}$Sr. Its complete characterization against a stationary lattice clock resulted in a systematic uncertainty of ${7.4 \times 10^{-17}}$ which is currently limited by the statistics of the determination of the residual lattice light shift. The measurements confirm that the systematic uncertainty is reduceable to below the design goal of $1 \times 10^{-17}$. The instability of our TOC is $1.3 \times 10^{-15}/\sqrt{(τ/s)}$. Both, the systematic uncertainty and the instability are to our best knowledge currently the best achieved with any type of transportable clock. For autonomous operation the TOC is installed in an air-conditioned car-trailer. It is suitable for chronometric leveling with sub-meter resolution as well as intercontinental cross-linking of optical clocks, which is essential for a redefiniton of the SI second. In addition, the TOC will be used for high precision experiments for fundamental science that are commonly tied to precise frequency measurements and it is a first step to space borne optical clocks
description: 6 pages 4 figures 1 table
Fuzzy linear regression with global continuous optimization
Creators: name: Mashinchi, M. Hadi
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Finding the global optimum of an unknown system has attracted a great deal of interest in many engineering problems. In this setting, meta-heuristics are very common and efficient approaches for solving complex real-world problems in Global Continuous Optimization Problems (GCOPs) as they can approximate solutions without any need for mathematical assumptions such as differentiability. The application of global continuous optimization methods is essential in many engineering applications where an optimization problem has certain properties such as unreliable derivatives and/or black-box nature. Meta-heuristic based optimizations, as one of the promising approaches in global continuous optimization, have a slow rate of convergence. Hybridization frameworks are investigated as a potential way of enhancing the optimization speed, and the quality of solutions. -- Fuzzy linear regression analysis is a powerful tool to model the input-output relationship for forcasting purposes or studying the behavior of the data. The existing challenges in fuzzy linear regression are, dealing with non-transparent fitness measures, outlier detection and spread increasing problem. The application of global continuous optimization is investigated to tackle these issues. We propose an Unconstrained Global Continuous Optimization (UGCO) method based on tabu search and harmony search to support the design of Fuzzy Linear Regression models (FLR). The proposed approach offers the flexibility of using any kind of an objective function based on the client's requirements or requests and the nature of the data set, and then attains its minimum error. -- Fuzzy linear analysis may lead to an incorrect interpretation of data in case of being incapable of dealing with outliers. Both basic probabilistic and least squares approaches are sensitive to outliers. In order to detect outliers, we propose a two stage least squares approach based on global continuous optimization which outperforms some issues that exist in other methods. In both the first and second phases, the minimization of the model fitting measurement is achieved by hybrid optimixation which gives us the fliexibility of using any type of model fitting measures regardless of being continuous, differentiable, or transparent. -- Some of the fuzzy linear regression models suffer from constantly increasing spreads of the outputs with the increase in the magnitude of the inputs. Such models are known to have the so-called spread increasing problem. We introduce a model, obtained by the application of hybrid optimization, which is capable of having variable spreads for different input variables regardless of their magnitude. The proposed approach is also compared and contrasted with other models in terms of the number of parameters, the flexibility of spreads, and errors.
Frame- and Segment-Level Features and Candidate Pool Evaluation for Video Caption Generation
Creators: name: Shetty, Rakshith
name: Laaksonen, Jorma
Publisher: name: arXiv
Year: 2016
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: We present our submission to the Microsoft Video to Language Challenge of generating short captions describing videos in the challenge dataset. Our model is based on the encoder--decoder pipeline, popular in image and video captioning systems. We propose to utilize two different kinds of video features, one to capture the video content in terms of objects and attributes, and the other to capture the motion and action information. Using these diverse features we train models specializing in two separate input sub-domains. We then train an evaluator model which is used to pick the best caption from the pool of candidates generated by these domain expert models. We argue that this approach is better suited for the current video captioning task, compared to using a single model, due to the diversity in the dataset. Efficacy of our method is proven by the fact that it was rated best in MSR Video to Language Challenge, as per human evaluation. Additionally, we were ranked second in the automatic evaluation metrics based table.
Direct measurement of the critical pore size in a model membrane
Creators: name: Ilton, Mark
name: DiMaria, Christian
name: Dalnoki-Veress, Kari
Publisher: name: arXiv
Year: 2016
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We study pore nucleation in a model membrane system, a freestanding polymer film. Nucleated pores smaller than a critical size close, while pores larger than the critical size grow. Holes of varying size were purposefully prepared in liquid polymer films, and their evolution in time was monitored using optical and atomic force microscopy to extract a critical radius. The critical radius scales linearly with film thickness for a homopolymer film. The results agree with a simple model which takes into account the energy cost due to surface area at the edge of the pore. The energy cost at the edge of the pore is experimentally varied by using a lamellar-forming diblock copolymer membrane. The underlying molecular architecture causes increased frustration at the pore edge resulting in an enhanced cost of pore formation.
description: 5 pages, 5 figures
Konrad Grafs Commentarius in Metaphysicam Aristotelis: Transkription aus der Handschrift Pp 183 4°, Teil 2, Zentral- und Hochschulbibliothek Luzern [ZHB], Sondersammlung.
Creators: name: Paladini, Chiara
Publisher: name: Zenodo
Year: 2023
Subjects: History of Philosophy
History of Metaphysics
History of Ontology
Swiss History
History of the Jesuits
Philosophy of the Early Modern Age
Second Scholasticism

description: Here I present the first version of the transcription of the Commentarius in Metaphysicam by Konrad Graf from Cod. Pp 183 4°, Teil 2, Zentral- und Hochschulbibliothek Luzern [ZHB], Sondersammlung (ff. 1r-56v), which collects Graf's lectures in metaphysics, held at the Lucerne Gymnasium in 1635-36. The transcription of the text was carried out at the Lucerne Faculty of Theology within the SNSF project "Zwischen monastischer und reformierter Metaphysik. Die schweizerische 'Wiege' der Ontologie im Zeitalter der Reformation" (SNSF project 100012_192559 - applicant: Prof. Dr. Giovanni Ventimiglia (TF- University of Lucerne), Employees: Marco Lamanna, Chiara Paladini. The project aimed to redefine the "cartography" of the Reformation in Switzerland on the traces of metaphysics teaching (Reportationes) in Swiss educational institutions and monastic poles, and thereby to gain a precise place for Swiss studies in the panorama of research on metaphysics and ontology in the early modern period. The project was based on a preliminary investigation that made it possible to recover new texts transmitting lessons on metaphysics held in Lucerne and Engelberg. The method was 1. to produce a systematic and comprehensive documentation based on an index of manuscripts and printed texts, most of them already identified, which testify to the existence of a cultural flourishing in Switzerland that has so far remained unexplored. 2. this documentation should be placed on a solid textual basis by transcribing and eventually critically editing those texts judged to be of interest in terms of their content and influence, in order to make them accessible to the scholarly community and to readers. 3. finally, we will examine the specific aspects of the teachings transmitted in these manuscripts.
description: The transcription was carried out as part of a project funded by the Swiss National Science Foundation (SNSF). Grant number: 192559
The organizing role of prior knowledge and advance organizers in chemical learning
Creators: name: West, Leo Henry Thomas
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
The RGS Protein Sst2 is Essential for Gradient Sensing in Mating Yeast
Creators: name: Bethanie-Michelle Statler
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: Chemotropism, or directed cell growth, depends on the ability of cells to accurately sense chemical gradients to properly establish cell polarity. During mating, the budding yeast Saccharomyces cerevisiae uses GPCRs to sense the pheromone secreted by mating partners. In response, yeast form a mating projection towards the nearest partner. The GPCR Ste2 is distributed uniformly on the plasma membrane in vegetative cells. Upon pheromone binding to the receptor, the activated G protein dissociates into Gα-GTP and Gβγ. It was previously thought that the receptor and G protein polarize directly to the chemotropic site (CS), in the direction of the pheromone source. We discovered that mating cells first polarize the receptor and G protein to the default polarity site (DS) before redistributing, or tracking, these proteins to the CS. The receptor and G protein then stabilize at the CS prior to morphogenesis. Sst2 stimulates the GTPase activity of Gα-GTP and preferentially binds to unphosphorylated receptor (Ballon et. al., 2006). Sst2 has been implicated in gradient sensing and proposed to act as a signaling barrier (Dixit et. al., 2014). We used time-lapse fluorescent microscopy to follow Sst2-GFP and Ste2-GFP localization in mating cells and ask how receptor tracking is affected in sst2∆ cells. Sst2 appeared at the DS after the receptor, started tracking before the receptor, and tracked from the DS to the CS like the receptor. Upon morphogenesis, Sst2 surrounded the receptor at the mating projection. Sst2 localization is likely determined by active-unphosphorylated receptor and Gα-GTP. This distribution is consistent with Sst2 serving as a signaling barrier. Notably, the receptor failed to track in sst2∆ cells, suggesting that the spatiotemporal dynamics of Sst2-catalyzed G-protein recycling is critical to gradient sensing.
Transkriptions- und Zoning-Guidelines für das Korpus Mastro (Mittelalterliche Stadtchroniken) Version 1.0
Creators: name: Hiltmann, Torsten
name: Odebrecht, Carolin
Publisher: name: Zenodo
Year: 2023

description: Transkriptions- und Zoning-Guidelines für das Korpus "MaStro – Korpus Mittelalterlicher Stadtchroniken – Bände, Version 1.0", verfügbar unter: https://www.laudatio-repository.org/browse/corpus/lFzOPIkBUnBk-z0fVtCF/corpora.
Relativistic k.p Hamiltonians for centrosymmetric topological insulators from ab initio wave functions
Creators: name: Nechaev, I. A.
name: Krasovskii, E. E.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present a method to microscopically derive a small-size k$\cdot$p Hamiltonian in a Hilbert space spanned by physically chosen ab initio spinor wave functions. Without imposing any complementary symmetry constraints, our formalism equally treats three- and two-dimensional systems and simultaneously yields the Hamiltonian parameters and the true $\mathbb{Z}_2$ topological invariant. We consider bulk crystals and thin films of Bi$_{2}$Se$_{3}$, Bi$_{2}$Te$_{3}$, and Sb$_{2}$Te$_{3}$. It turns out that the effective continuous k$\cdot$p models with open boundary conditions often incorrectly predict the topological character of thin films.
description: 6 pages, 4 figures, 1 table
Low-Intensity Vibration as a Treatment for Traumatic Muscle Injury
Creators: name: Corbiere, Thomas
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: Traumatic muscle injuries are a devastating consequence of motor vehicle accidents, limb salvage surgeries for the removal of tumors and military combat. These injuries are characterized by a significant loss of tissue and inadequate healing leading to impaired muscle function, joint stiffness, and loss of mobility. Low-intensity vibration (LIV) is a promising candidate for physical therapy that provides mechanical stimulation without requiring active muscle contraction. The goal of this study was to determine if LIV improves the healing of injured muscle and if these effects are mediated by IGF-1 and associated downstream pathways using a mouse model of laceration injury and a cell culture model of myoblast differentiation. We found that whole-body LIV (WBV) at 45 Hz and 0.4g increased myofiber area, while WBV at 90 Hz and 0.2g increased both myofiber area and diameter at day 14 in a mouse model of laceration injury. Additionally, we showed that local LIV at 90 Hz and 0.2g increased both myofiber area and diameter in injured muscle at day 14 post-injury while also increasing percent area of peripherally-nucleated myofibers (associated with mature muscle) and decreasing percent damaged area. These LIV-induced effects on muscle were not associated with an increase in IGF-1 protein or mRNA expression. Furthermore, LIV also increased differentiation and growth of cultured myotubes at day 6 post-differentiation. There was an increase in total Akt in muscle at the day 7 post-injury and in cultured myotubes at day 3 post-differentiation while, phosphorylated to total Akt ratio increased at day 14 post-injury in muscle and at day 6 post-differentiation in cultured myotubes. Taken together, LIV enhances growth of myofibers following laceration injury, muscle cells are capable of directly transducing LIV signals into enhanced differentiation and growth, and Akt may be involved in this process. Therefore, LIV could be a promising therapeutic option for the healing of traumatic muscle injury.
On the Riesz means of $δ_k(n)$
Creators: name: Singh, Saurabh Kumar
Publisher: name: arXiv
Year: 2016
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: Let $k\geq 1$ be an integer. Let $δ_k(n)$ denote the maximum divisor of $n$ which is co-prime to $k$. We study the error term of the general $m$-th Riesz mean of the arithmetical function $δ_k(n)$ for any positive integer $m \ge 1$, namely the error term $E_m(x)$ where \[ \frac{1}{m!}\sum_{n \leq x}δ_k(n) \left( 1-\frac{n}{x} \right)^m = M_{m, k}(x) + E_{m, k}(x). \] We establish a non-trivial upper bound for $\left | E_{m, k} (x) \right |$, for any integer $m\geq 1$.
Thiostrepton in Phospholipid Micelles: Development of Scalable Production Method and In Vivo Evaluation
Creators: name: Esparza, Karina
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: For over two decades, our laboratory has explored the use of sterically stabilized micelle (SSM) as a safe and practical nanocarrier for the delivery of water-insoluble drugs and amphiphilic peptides. This nanocarrier is composed of distearoyl phosphatidylethanolamine-polyethylene glycol 2000 (DSPE-PEG2000), a biodegradable and biocompatible ingredient that self-assembles in aqueous media above the micellar concentration forming a nanocarrier with a hydrophobic core and a PEGylated hydrophilic shell. However, our group has identified two important limitations with this nanocarrier: (1) loss of drug activity upon encapsulation of charged amphiphilic antibiotics in SSM and (2) lack of scalability of the conventional hydrophobic drug encapsulation method for industrial purposes. To address these challenges, we selected the hydrophobic non-charged antibiotic thiostrepton (TST) as a better antimicrobial drug candidate for delivery in SSM and developed a novel scalable drug encapsulation method using co-solvent freeze-drying. Our hypothesis was that TST could be encapsulated into SSM using a scalable co-solvent freeze-drying method to provide a stable, safe, and effective nanomedicine against resistant staphylococcal pneumonia and sepsis. By systematically altering key process parameters of the co-solvent freeze-drying method, we identified ideal process conditions to generate an optimized stable TST-SSM nanomedicine with drug loading similar to the thin-film hydration method (5 drug molecules per micelle). TST-SSM nanomedicine was 4-8-fold more active than free TST dissolved in 4% DMSO against various Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA) USA300. This result was because SSM protected TST from degradation at the bacterial media. We evaluated the antibiotic activity of TST-SSM in a murine model of MRSA pneumonia but found no significant changes possibly due to the interference of the anti-inflammatory activity of TST which inhibits the immune response required for efficient bacterial clearance. On the other hand, TST-SSM exhibited significant improvement in the survival and inflammatory markers of mice with polymicrobial sepsis induced by cecum ligation and puncture. These results are likely due to the reported TLR-9 inhibitory activity of TST which reduces the exacerbated host inflammatory activity characteristic of sepsis. In conclusion, we developed a new TST-SSM nanomedicine using a scalable co-solvent freeze-drying method that is suitable for large scale production and can facilitate the clinical translation of TST-SSM nanomedicine for the treatment of sepsis and possibly other immunological disorders.
A story of instructional research and simulation in aviation (air traffic control)
Creators: name: Webster, Leonard L.
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Mechanisms of Action of Ribosome-Binding Antimicrobial Peptides
Creators: name: Florin, Tanja
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: Today’s urgent need for better antibiotics calls for multifaceted approaches not only to search for new compounds but also to understand their mode of action to develop them as effective inhibitors of microbial growth. As contributors to this task, our lab focuses on deciphering the molecular mechanisms of antimicrobials that target the protein synthesis process in bacteria. Antimicrobial peptides (AMPs) have recently gained attention as promising candidates for new antibiotics. AMPs are produced by organisms of all kingdoms to protect themselves from bacterial infections. AMPs are structurally dissimilar and have a diverse array of bacterial targets. In these studies, we are demonstrating that two different types of AMPs, odilorhabdins (ODLs) and proline-rich antimicrobial peptides (PrAMPs), inhibit protein synthesis by targeting the ribosome. However, their binding sites within the ribosome and their strategies to stop protein synthesis are completely different and novel. The bacterium Xenorhabdus nematophila produces ODLs to kill competing bacteria co-residing in the nematode host. By binding to a unique location of the ribosome, ODLs can affect protein synthesis in two ways: at low concentrations, they cause ribosomes to make mistakes, while high concentrations block the assembly of new proteins. Importantly, the inhibitory action of ODLs effectively eradicates infections caused by drug-resistant bacteria in mice, a property that has advanced ODLs into the antibiotic development pipeline. As part of their immune systems, insects, crustaceans, and mammals produce PrAMPs. A common feature of PrAMPs is that they enter the exit tunnel through which newly made proteins leave the ribosome. Once inside the tunnel, while type I PrAMPs, i.e. Onc112 and Bac7, stop ribosomes from starting to make proteins, type II PrAMP Apidaecin allows assembly of the entire protein but impedes its release from the ribosome. Besides contributing to design of treatments for bacterial infections, the knowledge of the detailed mechanisms of action of AMPs extends beyond their application as pharmaceutical drugs. For example, Onc112 was used as a tool to discover new bacterial genes and we are taking advantage of the inhibitory properties of Apidaecin to develop molecular biology screens and to study translation regulation in a variety of organisms.
Stimulated Brillouin scattering enhancement in silicon inverse opal waveguides
Creators: name: Smith, M. J. A.
name: Wolff, C.
name: de Sterke, C. Martijn
name: Lapine, M.
name: Kuhlmey, B. T.
name: Poulton, C. G.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Silicon is an ideal material for on-chip applications, however its poor acoustic properties limit its performance for important optoacoustic applications, particularly for Stimulated Brillouin Scattering (SBS). We theoretically show that silicon inverse opals exhibit a strongly improved acoustic performance that enhances the bulk SBS gain coefficient by more than two orders of magnitude. We also design a waveguide that incorporates silicon inverse opals and which has SBS gain values that are comparable with chalcogenide glass waveguides. This research opens new directions for opto-acoustic applications in on-chip material systems.
description: 4 pages, 6 figures
Bi+ People’s Experiences in the Post Gay Era
Creators: name: Lain Mathers
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: In this dissertation, I draw on 40 in-depth interviews with bi+ people between the ages of 21 and 30 in the Chicagoland area to better understand the ways they construct identity, navigate forming connections to LGBTQ and bi+ community, and conceptualize social changes that would impact bi+ people. My findings suggest that bi+ people navigate pervasive stigma and construct their identities in relation to these stigmas. They struggled to find community with other bi+ people in the wake of this exclusion. Interviewees showed difficulty naming a core issue for bi+ people beyond increasing visibility. My findings suggest this is because they may not have a solid network of people with a shared bi+ consciousness when it comes to major political concerns. These findings suggest that monosexism is reproduced through social interaction, and my analysis reveals some of the pathways by which this happens. I coin the term “the monosexual imaginary” to highlight how bi+ existence is rendered invisible and monosexism is maintained in contemporary U.S. society.
Long-term ENSO prediction with echo-state networks
Creators: name: Hassanibesheli, Forough
name: Kurths, Jürgen
name: Boers, Niklas
Publisher: name: Humboldt-Universität zu Berlin
Year: 2022
Subjects: subject: ENSO
subject: artificial neural networks
subject: echo state network
subject: 550 Geowissenschaften

description: The El Niño-Southern Oscillation (ENSO) is a climate phenomenon that profoundly impacts weather patterns and extreme events worldwide. Here we develop a method based on a recurrent neural network, called echo state network (ESN), which can be trained efficiently to predict different ENSO indices despite their relatively high noise levels. To achieve this, we train the ESN model on the low-frequency variability of ENSO indices and estimate the potential future high-frequency variability from specific samples of its past history. Our method reveals the importance of cross-scale interactions in the mechanisms underlying ENSO and skilfully predicts its variability and especially El Niño events at lead times up to 21 months. This study considers forecasts skillful if the correlation coefficients are above 0.5. Our results show that the low-frequency component of ENSO carries substantial predictive power, which can be exploited by training our model on single scalar time series. The proposed machine learning method for data-driven modeling can be readily applied to other time series, e.g. finance and physiology. However, it should be noted that our approach cannot straightforwardly be turned into a real-time operational forecast because of the decomposition of the original time series into the slow and fast components using low-pass filter techniques.
The national school system in Victoria, 1848-1962 : its origins and perspective
Creators: name: Waugh, Maxwell Neil
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Biased Antagonists of CXCR4 Avoid the Development of Antagonist Tolerance
Creators: name: Hitchinson, Ben
Publisher: name: University of Illinois at Chicago
Year: 2020
Subjects: Uncategorized

description: Despite reported tolerance to antagonists of multiple GPCRs, very few studies provide mechanistic insight and strategies to avoid it [50, 133, 134]. Tolerance to the only FDA–approved CXCR4 receptor antagonist AMD3100 can occur and significantly limits the potential to target the receptor in a variety of pathologies [50]. This tolerance is associated with increased receptor expression on the cell surface. In this thesis, we have investigated the mechanism of tolerance to AMD3100 and developed strategies to avoid it. We hypothesize that accumulation of CXCR4 on the cell surface leads to the development of tolerance, at least in part, due to the inhibition of receptor endocytosis by AMD3100. Thus, we hypothesized that antagonists that inhibited G protein signalling but not receptor endocytosis would avoid the development of tolerance. Few compounds of this type, called biased antagonists, have been discovered [135, 136]. By understanding the mechanisms through which tolerance develops, we believe that future pharmaceutical development will benefit from rational design of inhibitors that avoid these processes.
Improper ferroelectricity in stuffed aluminate sodalites for pyroelectric energy harvesting
Creators: name: Maeda, Yusaku
name: Wakamatsu, Toru
name: Konishi, Ayako
name: Moriwake, Hiroki
name: Moriyoshi, Chikako
name: Kuroiwa, Yoshihiro
name: Tanabe, Kenji
name: Terasaki, Ichiro
name: Taniguchi, Hiroki
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Ferroelectricity in stuffed aluminate sodalites is demonstrated in the present study. The present results indicate that stuffed aluminate sodalites exhibit excellent performance as a pyroelectric energy harvester, suggesting that they exhibit great promise as a class of materials for highly efficient energy harvesting devices. (See manuscript for the full abstract)
Fully gapped superconducting state in Au2Pb: a natural candidate for topological superconductor
Creators: name: Yu, Y. J.
name: Xu, Y.
name: Xing, Y.
name: Zhang, J.
name: Ying, T. P.
name: Hong, X. C.
name: Wang, M. X.
name: Zhang, X.
name: Jia, S.
name: Wang, J.
name: Li, S. Y.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We measured the ultra-low-temperature specific heat and thermal conductivity of Au$_2$Pb single crystal, a possible three-dimensional Dirac semimetal with a superconducting transition temperature $T_c \approx$ 1.05 K. The electronic specific heat can be fitted by a two-band s-wave model, which gives the gap amplitudes $Δ_1$(0)/$k_BT_c$ = 1.38 and $Δ_2$(0)/$k_BT_c$ = 5.25. From the thermal conductivity measurements, a negligible residual linear term $κ_0/T$ in zero field and a slow field dependence of $κ_0/T$ at low field are obtained. These results suggest that Au$_2$Pb has a fully gapped superconducting state in the bulk, which is a necessary condition for topological superconductor if Au$_2$Pb is indeed one.
description: 6 pages, 4 figures
El Contrato de Construcción en Chile y la alternativa de la Estandarización.pdf
Creators: name: Vergara Bularz, Victor
Publisher: name: figshare
Year: 2023
Subjects: Construction engineering
Building construction management and project planning
Contract law
Conflict of laws (incl. private international law)

description: La construcción es una de las principales actividades y motores de la economía en Chile. Las cifras en torno a la actividad son cuantiosas y es una de las más sensibles a los ciclos de la economía, tanto por la velocidad con la que reacciona, como por la magnitud de su respuesta, además de tener un alto grado de significancia en el empleo. Las características propias de la ejecución de proyectos de ingeniería y construcción, entre estos, altos montos de inversión, ejecución dentro de plazos extensos y la intervención de diferentes profesionales, hacen que posea altos niveles de conflictividad entre los intervinientes, que repercuten directamente en el presupuesto estimado, los plazos previstos y que, incluso, pueden conllevar al fracaso o paralización de una obra determinada (Solminihac, 2020). Las cifras sobre conflictividad, medidas en aumento de costos y en extensiones de plazos en el desarrollo de los proyectos de infraestructura son considerables, tanto en Chile como en la experiencia comparada. Las formas contractuales utilizadas en tales proyectos son disímiles y comprenden desde documentos elaborados a medida por las partes, otros dados por el Ordenamiento Jurídico y otros que son el resultado de la estandarización contractual. No existe literatura concluyente sobre si el uso de un determinado tipo contractual contribuye a la disminución de conflictos. Las publicaciones sobre contratos estandarizados ponen de manifiesto sus virtudes, sin embargo, no entregan cifras comparativas entre contratos estandarizados y aquellos desarrollados a medida, que son los predominantemente utilizados en Chile. El presente trabajo busca evidenciar, de acuerdo a una evaluación crítica, la estructura del contrato de construcción, observando las formas contractuales que se utilizan en Chile, con la finalidad de compararlas con aquellas formas contractuales estandarizadas utilizadas en la experiencia comparada y verificar si existe una disparidad en sus resultados desde una perspectiva de controversias y litigiosidad.
Measurement of Exclusive $\pi^{+}\pi^{-}$ and $\rho^0$ Meson Photoproduction at HERA
Creators: name: H1 Collaboration
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2020
Subjects: pi: decay
meson: photoproduction
meson: mass
resonance: production
photon: dissociation
lead: production
photon: model
DESY HERA Stor
Regge poles
phase space
scattering
slope
Regge

description: Exclusive photoproduction of $\rho^0(770)$ mesons is studied using the H1 detector at the $ep$ collider HERA. A sample of about 900000 events is used to measure single- and double-differential cross sections for the reaction $\gamma p \to \pi^{+}\pi^{-}Y$. Reactions where the proton stays intact (${m_Y{=}m_p}$) are statistically separated from those where the proton dissociates to a low-mass hadronic system ($m_p{
Diphotons at the $Z$-pole in Models of the 750 GeV Resonance Decaying to Axion-Like Particles
Creators: name: Alves, Alexandre
name: Dias, Alex G.
name: Sinha, Kuver
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Models in which the 750 GeV resonance ($S$) decays to two light axion-like particles (ALPs $a$), which in turn decay to collimated photons mimicking the observed signal, are motivated by Hidden Valley scenarios and could also provide a mechanism by which a $S \to γγ$ signal persists while $S \to Z γ,\; ZZ$ and $WW$ remain subdued in the near future. We point out that these Hidden Valley like models invoking $S \to aa \to 4 γ$ must also contend with $Z \to a (\to γγ) γ$ constraints coming from CDF and ATLAS. Within an effective field theory framework, we work out the constraints on the couplings of $S$ to $a$ and gauge bosons coming from photonic $Z$ decays and ensuring that the ALPs decay inside the electromagnetic calorimeter, in two regimes - where $a$ decays primarily to photons, and where $a$ also has hadronic branchings. The analysis is done for both when $S$ has a large as well as a narrow width, and for different relative contributions to the signal coming from $S \to γγ$ and $a \to γγ$. Results for the particular case where $S$ and $a$ belong to the same complex field are also presented. A $γγ$ resonance at the $Z$-pole coming from $Z \to a γ$ is expected in this class of models. Taking benchmark ALP masses below around 0.4 GeV and, assuming reasonable values for the fake jet rate and the identification efficiency of the photon-jet, we find the prospects for the discovery of diphotons at the $Z$-pole.
description: 19 pages, 11 figures
The experience of river places in outdoor education : a phenomenological study
Creators: name: Wattchow, Brian James
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field. Winner of the Mollie Holman Doctoral Medal for Excellence