cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Bridging the gap between web interfaces and notebooks in the eWaterCycle II project
Creators: name: Drost, Niels
name: Hut, Rolf
name: van de Giesen, Nick
name: van Werkhoven, Ben
name: Aerts, Jerom
name: Pelupessy, Inti
name: Weel, Berend
name: Dzigan, Yifat
name: de Vos, Martine
name: Verhoeven, Stefan
name: van den Oord, Gijs
name: van Haren, Ronald
name: van der Zwaan, Janneke
name: van Meersbergen, Maarten
Publisher: name: Zenodo
Year: 2019

description: A large number of online systems for creating, processing, or analyzing scientific data exist. More and more such an online environment is seen as the ideal way to give users quick and easy access to large amounts of data, software, and hardware resources. Often these systems provide a web interface for easy access and exploration of the available data. Recently, notebook environments are becoming popular for providing advanced access to large datasets and HPC resources. When designing and building an online system, developers are often faced with a choice: either provide a ready made user interface, with limited options for users, or provide a notebook environment, requiring advanced knowledge about the system from a user to use effectively, hindering explorative use.

In the eWaterCycle II project (www.ewatercycle.org) we provide a novel solution to this problem: We have created a web interface allowing a user to select models, data, and other options, from a pre-made set. Our system is then capable of generating a notebook specifically for the settings chosen by the user. This notebook can be run by the users to do the requested computation or analysis (in our case running a Hydrological model and providing a first hydrograph). It also forms the perfect basis for a user to start tinkering with the experiment, and change it any way she or he sees fit. This method thus allows novice users to get going quickly, while still allowing advanced users all the freedom they require.

Our system is build on and would not be possible without Free and Open Source Software (FOSS). Our data and model explorer is based on a modified version of Terriajs. The notebook generator builds on OpenAPI to provide a service to create Jupyter notebooks, and in turn calls a JupyterHub service. Of course all our software is available as FOSS, available at https://github.com/eWaterCycle.
Shielding of a small charged particle in weakly ionized plasmas
Creators: name: Chaudhuri, Manis
name: Khrapak, Sergey A.
name: Kompaneets, Roman
name: Morfill, Gregor E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In this paper we present a concise overview of our recent results concerning the electric potential distribution around a small charged particle in weakly ionized plasmas. A number of different effects which influence plasma screening properties are considered. Some consequences of the results are discussed, mostly in the context of complex (dusty) plasmas.
description: This is a short review paper
Spin and Valley Splittings in Multilayered Massless Dirac Fermion System
Creators: name: Tajima, N.
name: Sato, M.
name: Sugawara, S.
name: Kato, R.
name: Nishio, Y.
name: Kajita, K.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The inter-layer magnetoresistance in a multilayered massless Dirac fermion system, $α$-(BEDT-TTF)$_2$I$_3$, under hydrostatic pressure was investigated. We succeeded in detecting the zero-mode (n=0) Landau level and its spin splitting in the magnetic field normal to the 2D plane. We demonstrated that the effective Coulomb interaction in the magnetic field intensifies the spin splitting of zero-mode Landau carriers. At temperatures below 2K, magnetic fields above several Tesla break the twofold valley degeneracy.
description: 4 page, 4 figures
title: Welfare assessment of fatal methaemoglobinaemia in adult rats (Rattus norvegicus)
Creators: name: Gibson, T.J.
name: Gregory, N.G.
name: Quy, R.J.
name: Eason, C.T.
Publisher: name: Julius Kühn-Institut
Year: 2011
Subjects: subject: cerebral depression
subject: death
subject: methaemoglobinaemia
subject: methaemoglobin (MetHb)
subject: welfare

description: Julius-Kühn-Archiv; 432; 148-149
General polarization modes for the Rosen gravitational wave
Creators: name: Cropp, Bethan
name: Visser, Matt
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Strong-field gravitational plane waves are often represented in either the Rosen or Brinkmann forms. While these two metric ansatze are related by a coordinate transformation, so that they should describe essentially the same physics, they rather puzzlingly seem to treat polarization states quite differently. Both ansatze deal equally well with + and X linear polarizations, but there is a qualitative difference in they way they deal with circular, elliptic, and more general polarization states. In this article we will develop a general formalism for dealing with arbitrary polarization states in the Rosen form of the gravitational wave metric, representing an arbitrary polarization by a trajectory in a suitably defined two dimensional hyperbolic plane.
description: V1: 12 pages, no figures. V2: still 12 pages, reformatted. Minor technical edits, discussion of Riemann tensor added, two references added, no significant physics changes. This version accepted for publication in Classical and Quantum Gravity
title: Automatic and permanent rodent-monitoring - a proper method to evaluate rodenticide effects?
Creators: name: Fuelling, O.
name: Klemann, N.
name: Endepols, S.
Publisher: name: Julius Kühn-Institut
Year: 2011
Subjects: subject: EPPO guideline
subject: monitoring
subject: Mus musculus
subject: Rattus norvegicus
subject: registration
subject: rodentic

description: Julius-Kühn-Archiv; 432; 150-151
The Link between General Relativity and Shape Dynamics
Creators: name: Gomes, Henrique
name: Koslowski, Tim
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show that one can construct two equivalent gauge theories from a linking theory and give a general construction principle for linking theories which we use to construct a linking theory that proves the equivalence of General Relativity and Shape Dynamics, a theory with fixed foliation but spatial conformal invariance. This streamlines the rather complicated construction of this equivalence performed previously. We use this streamlined argument to extend the result to General Relativity with asymptotically flat boundary conditions. The improved understanding of linking theories naturally leads to the Lagrangian formulation of Shape Dynamics, which allows us to partially relate the degrees of freedom.
description: 19 pages, LaTeX, no figures
Soybean roots defence against cadmium and its dependence on dose in a non-linear manner
Creators: name: Mészáros, Patrik
name: Rybanský, Ľubomír
name: Bardáčová, Monika
name: Roszival, Marcel
name: Matušíková, Ildikó
Publisher: name: Brill Online
Year: 2021
Subjects: subject: 60299 Ecology not elsewhere classified
subject: FOS: Biological sciences

description: Metal pollution represents a serious issue for sustainable agronomy and food safety. Activation of plants' protective mechanisms has been shown to depend on the extent of soil contamination with metal, but reports on dose-dependent responses (especially to extreme concentrations) are rather rare. In this research we exposed soybean (Glycine max L.) roots at a very early stage to a scale of cadmium concentrations, including doses far exceeding the amounts found in nature. Spectrophotometrical and enzyme in-gel detection assays were used to examine ongoing defence responses. The results confirmed commonly reported findings on inhibited growth and the activation of several superoxide dismutase isoforms in a dose-dependent manner. Contrary to expectations, the hydrogen peroxide levels, proline accumulation and the rate of lipid peroxidation were suppressed with increasing metal doses. More importantly, the linearity of Cd accumulation in soybean roots was interrupted at 200 mg.l-1 of cadmium, which coincides with peculiar responses of several chitinase family members. No such nonlinear response was observable for proline accumulation or any of the SOD isoforms. Possible explanations are provided and the importance of considering the metal stress dose is stressed to avoid false generalizations on plant defence responses.
Synthesis and structure-activity relationship study of benzofuran-based chalconoids bearing benzylpyridinium moiety as potent acetylcholinesterase inhibitors
Creators: name: Ziarani, Ghodsi Mohammadi
Publisher: name: figshare
Year: 2021
Subjects: subject: Organic Chemistry
subject: FOS: Chemical sciences
subject: 30201 Bioinorganic Chemistry
subject: 30504 Organic Green Chemistry

description: A series of benzofuran-based chalconoids 6a–v were designed and synthesized as new potential AChE inhibitors. The in vitro assay of synthesized compounds 6a–v showed that most compounds had significant anti-AChE activity at micromolar or sub-micromolar levels. Among the tested compounds, 3-pyridinium derivative 6m bearing N-(2-bromobenzyl) moiety and 7-methoxy substituent on the benzofuran ring exhibited superior activity. This compound with IC50 value of 0.027 μM was as potent as standard drug donepezil
The creativity of social innovation : a complex systems framework for social systems intervention
Creators: name: Unrau, Mike
Publisher: name: University of British Columbia
Year: 2022

description: This manuscript-style dissertation assists to fill the gap in the social innovation literature of social intervention methods that account for worldview bias and the nonlinear dynamical processes of social systems innovation. I investigate a critical consciousness approach to worldview bias and link the result to a nonlinear dynamical approach to creativity in systems transformation so that social innovators may uncover novel transitions in systems dynamics and generate creative solution spaces for beneficial change. The dissertation results in a transdisciplinary theoretical framework for “systemic-dynamic creativity” and four publishable manuscripts on key topics that help guide changemakers in an internal and external reflexive process on social innovation. In the first manuscript I investigate an “internal” approach to Freire’s critical consciousness and how it relates to a complex systems approach to creative consciousness. I show that by making novel distinctions between static and dynamic worldviews, social innovators may become mindfully aware and transform internal bias. In the next manuscript, I move to an “external” approach and examine nonlinear dynamical systems theory to identify the “birthplace” of creativity as it arises applies to multiple systems. I produce a novelty assessment that can aid changemakers in finding “transition points” for systemic innovation, and offer four preconditions to novelty to leverage such points in a Meadows-like intervention toward systemic change. In the third manuscript, I take this nonlinear understanding, apply it to social systems, and find that Schumpeter’s “creative destruction” resembles entropic processes of disordering also found in collective worldviews. I show that the oppositional “negentropic” processes may transform social complexities toward the ordering of creative solutions. Such “internal” and “external” approaches to social change are then synthesized in the fourth manuscript, where I build upon other social innovation methodologies (e.g., Checkland’s soft systems methodology and “social labs”) to generate a method informed by nonlinear dynamics and worldview bias considerations for social innovation intervention. The four publishable manuscripts contribute to scholarship on creativity and social innovation by offering a conception of “creative critical consciousness,” a low-recurrence approach to novelty generation, and a practical social innovation method for changemakers to use when addressing complex social systems challenges.
title: Integrating ecology and technology to create innovative pest control devices
Creators: name: Blackie, H.
name: MacMorran, D.
name: Shapiro, L.
name: Woodhead, I.
name: Diegel, O.
name: Murphy, E.
name: Eason, C.T.
Publisher: name: Julius Kühn-Institut
Year: 2011
Subjects: subject: Mustela erminea
subject: para-aminopropiophenone
subject: resetting toxin delivery systems

description: Julius-Kühn-Archiv; 432; 152-153
Papers in Southeast Asian Linguistics No. 8: Tonation
Creators: name: Bradley, David (Ed.)
Publisher: name: Pacific Linguistics
Year: 1982

description: A-62
description: Contents iiiINTRODUCTION. {David Bradley} vi{Philip John Rose} 1 ACOUSTIC CHARACTERISTICS OF THE SHANGHAI-ZHENHAI SYLLABLE TYPES. 0. Introduction 1 1. Previous Studies 3 2. Syllable-Types 3 3. Syllable Structure 5 4. Procedure (General) 5 5. Procedure (Mensural) and Instrumentation 7 6. Results 10 7. Discussion 11 8. Fundamental Frequency 37 9. Duration 38 10. Amplitude 39 11 Interparametric Correlations - F₀ and A₀ 40 12. Interparametric Correlations - F₀ and Duration 43 13. Effect of Syllable-Final Velar Nasal 45 14. Final Nasal and F₀ 45 15. Nasal Onset Point and Duration 46 16. Effect of Initial Sonorant 47 17. Summary 48Notes 49 Bibliography 51{Vũ Thanh Phương} 55PHONETIC PROPERTIES OF VIETNAMESE TONES ACROSS DIALECTS. 0. Introduction 55 1. An Overview of Vietnamese Tones 55 2. Procedures 57 2.1. Informants 57 2.2. Word Lists 57 2.3. Instruments 57 2.4. Measurements 57 3. Results 59 4. Discussion 68 4.1. Physical Phonetic Parameters in Normalised Values 68 4.2. Common Characteristics and Differences 70 5. Conclusion 74Notes 75Bibliography 76Map 58{U Thein Tun} 77SOME ACOUSTIC PROPERTIES OF TONES IN BURMESE. 1. Phonological Tones 77 2. Experiment 1 78 3. Experiment 2 82 4. Tables Showing the Average Lengths of the Tones 85 4.1. Total Lengths of the Tones 87 5. Component Durations of the Monophthongal Nuclei 92 6. Component Durations of the Diphthongal Nuclei 93 7. Conclusion from the Two Experiments 93 8. Experiment 3 93 8.1. Spectral Qualities of the Tones on Vocalic Nuclei 93 8.2. Monophthongal Nuclei 94 8.3. Non-Nasalised Monophthongal Nuclei 94 8.4. Nasalised Monophthongal Nuclei 97 8.5. Diphthongal Nuclei 102 8.6. Method of Measuring 102 9. General Conclusion from the Three Experiments 114Bibliography 115{David Bradley} 117REGISTER IN BURMESE. 0. Introduction 117 1. Prosodies in Burmese 120 2. Burmese as a Register Language 122 3. Burmese and Austroasiatic 127Notes 130Bibliography 131{Anthony Diller} 133A NEW HIGH TONE IN SOUTHERN THAI. 0. Introduction 133 1. KIHT: Tonogenesis-in-progress 133 2. Kra Isthmus Tonal Systems 134 3. The Origin of KIHT 138 4. Retention and Loss of Final Stops in Tai 143 5. Sociolinguistic Confrontation 144 6. Tai Tones and Tonogenetic Theory 147Notes 151Bibliography 153{Jack Gandour and Mary Jane Gandour} 155THE RELATIVE FREQUENCY OF TONES IN THAI. 0. Introduction 155 1. Method 155 2. Results and Discussion 156Bibliography 158
Exact spin quantum Hall current between boundaries of a lattice strip
Creators: name: de Gier, Jan
name: Nienhuis, Bernard
name: Ponsaing, Anita
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Employing an inhomogeneous solvable lattice model, we derive an exact expression for a boundary-to-boundary edge current on a lattice of finite width. This current is an example of a class of parafermionic observables recently introduced in an attempt to rigorously prove conformal invariance of the scaling limit of critical two-dimensional lattice models. It also corresponds to the spin current at the spin-Quantum Hall transition in a model introduced by Chalker and Coddington, and generalized by Gruzberg, Ludwig and Read. Our result is derived from a solution of the $q$-deformed Knizhnik-Zamolodchikov equation, and is expressed in terms of a symplectic Toda-lattice wave-function.
description: 22 pages, 26 postscript figures, revised version
Dark Matter Annihilation Signatures from Electroweak Bremsstrahlung
Creators: name: Bell, Nicole F.
name: Dent, James B.
name: Jacques, Thomas D.
name: Weiler, Thomas J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We examine observational signatures of dark matter annihilation in the Milky Way arising from electroweak bremsstrahlung contributions to the annihilation cross section. It has been known for some time that photon bremsstrahlung may significantly boost DM annihilation yields. Recently, we have shown that electroweak bremsstrahlung of W and Z gauge bosons can be the dominant annihilation channel in some popular models with helicity-suppressed 2 --> 2 annihilation. W/Z-bremsstrahlung is particularly interesting because the gauge bosons produced via annihilation subsequently decay to produce large correlated fluxes of electrons, positrons, neutrinos, hadrons (including antiprotons) and gamma rays, which are all of importance in indirect dark matter searches. Here we calculate the spectra of stable annihilation products produced via gamma/W/Z-bremsstrahlung. After modifying the fluxes to account for the propagation through the Galaxy, we set upper bounds on the annihilation cross section via a comparison with observational data. We show that stringent cosmic ray antiproton limits preclude a sizable dark matter contribution to observed cosmic ray positron fluxes in the class of models for which the bremsstrahlung processes dominate.
description: 11 pages, 6 figures. Updated to match PRD version
title: Searching for alternative methods for a sustainable population management of the common vole (Microtus arvalis) in Saxony-Anhalt
Creators: name: Eggert, J.
name: Wolff, C.
name: Richter, K.
Publisher: name: Julius Kühn-Institut
Year: 2011
Subjects: subject: common vole
subject: gradation
subject: Microtus arvalis
subject: Sachsen-Anhalt
subject: Saxony-Anhalt
subject: tillage
subject: weather

description: Julius-Kühn-Archiv; 432; 154-155
Comment on "The quantum mechanics of electric conduction in crystals," by R. J. Olsen and G. Vignale [Am. J. Phys. 78 (9), 954-960 (2010)]
Creators: name: de Bianchi, Massimiliano Sassoli
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this note we use the notion of time-delay to explain the physical content of the transformation properties of transmission and reflection amplitudes, as a result of a displacement of the potential. Then, we reconsider the recent analysis of the scattering problem by a finite-periodic potential, by Olsen and Vignale, to obtain the total reflection condition in the limit of an infinite number of cells. In doing this, we obtain an expression of Hartman's effect, showing that the group velocity of the transmitted particle inside the potential chain can become arbitrary large, as the number of cells tends to infinity.
description: To be published in the Am. J. Phys., together with a reply from the authors
Stationary points approach to thermodynamic phase transitions
Creators: name: Kastner, Michael
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Nonanalyticities of thermodynamic functions are studied by adopting an approach based on stationary points of the potential energy. For finite systems, each stationary point is found to cause a nonanalyticity in the microcanonical entropy, and the functional form of this nonanalytic term is derived explicitly. With increasing system size, the order of the nonanalytic term grows, leading to an increasing differentiability of the entropy. It is found that only "asymptotically flat" stationary points may cause a nonanalyticity that survives in the thermodynamic limit, and this property is used to derive an analytic criterion establishing the existence or absence of phase transitions. We sketch how this result can be employed to analytically compute transition energies of classical spin models.
description: 5 pages, 2 figures. Contribution to the proceedings of the 11th Granada Seminar on Computational Physics
Rod-structure classification of gravitational instantons with U(1)xU(1) isometry
Creators: name: Chen, Yu
name: Teo, Edward
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The rod-structure formalism has played an important role in the study of black holes in D=4 and 5 dimensions with RxU(1)^{D-3} isometry. In this paper, we apply this formalism to the study of four-dimensional gravitational instantons with U(1)xU(1) isometry, which could serve as spatial backgrounds for five-dimensional black holes. We first introduce a stronger version of the rod structure with the rod directions appropriately normalised, and show how the regularity conditions can be read off from it. Requiring the absence of conical and orbifold singularities will in general impose periodicity conditions on the coordinates, and we illustrate this by considering known gravitational instantons in this class. Some previous results regarding certain gravitational instantons are clarified in the process. Finally, we show how the rod-structure formalism is able to provide a classification of gravitational instantons, and speculate on the existence of possible new gravitational instantons.
description: 43 pages, 5 figures, LaTeX; minor changes made and reference added, published version
title: The development of a light-weight, long-life diphacinone rodent bait
Creators: name: Ross, J.G.
name: Eason, C.T.
name: Sam, S.
name: Shapiro, L.
name: Blackie, H.
name: MacMorran, D.
name: Aylett, P.
name: Tucker, N.
name: Razzaq, H.
Publisher: name: Julius Kühn-Institut
Year: 2011
Subjects: subject: diphacinone
subject: long-life bait
subject: mice
subject: rats
subject: rodent control

description: Julius-Kühn-Archiv; 432; 156
title: ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¿ÐµÑÐµÑ Ð¾Ð´Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð¿ÑÐ¾ÑÐ¸Ð²Ð»ÐµÐ½Ð¸Ñ Ð²Ð°ÐºÑÑÐ¼Ð½ÑÑ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»ÐµÐ¹ Ð² Ð¿ÑÐ¾ÑÐµÑÑÐµ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Investigation of the transition resistance of vacuum circuit breakers during operation
Creators: name: ÐÐ¾Ð²ÐµÑÐ¾Ð², ÐÐµÑÐ¼Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð²Ð°ÐºÑÑÐ¼Ð½ÑÐµ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»Ð¸
Ð¿ÐµÑÐµÑ Ð¾Ð´Ð½Ð¾Ðµ ÑÐ¾Ð¿ÑÐ¾ÑÐ¸Ð²Ð»ÐµÐ½Ð¸Ðµ
ÑÐ¼Ð¸ÑÑÐ¸Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¾Ð²
ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ñ Ð²Ð°ÐºÑÑÐ¼Ð½ÑÑ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»ÐµÐ¹
vacuum circuit breakers
transient resistance
electron emission
operation of vacuum circuit breakers

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½ Ð¿ÑÐ¾ÑÐµÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÐµÑÐµÑÐ¾Ð´Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð¿ÑÐ¾ÑÐ¸Ð²Ð»ÐµÐ½Ð¸Ñ Ð²Ð°ÐºÑÑÐ¼Ð½Ð¾Ð³Ð¾ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»Ñ. ÐÐ°Ð½Ñ Ð¾Ð±ÑÐ¸Ðµ Ð¿Ð¾Ð½ÑÑÐ¸Ñ Ð¸ ÑÐµÑÐ¼Ð¸Ð½Ñ, Ð¾ÑÐ½Ð¾ÑÑÑÐ¸ÐµÑÑ Ðº ÑÐµÐ¼Ðµ Ð²Ð°ÐºÑÑÐ¼Ð½ÑÑ Ð²ÑÐºÐ»ÑÑÐ°ÑÐµÐ»ÐµÐ¹, ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¸Ñ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ñ, ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸Ñ Ðº Ð½Ð¸Ð¼ Ð¸ Ð¸Ñ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿ Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð·Ð°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÐµÐ¹ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº, Ð²Ð»Ð¸ÑÑÑÐ¸Ñ Ð½Ð° Ð¿ÐµÑÐµÑÐ¾Ð´Ð½Ð¾Ðµ ÐºÐ¾Ð½ÑÐ°ÐºÑÐ½Ð¾Ðµ ÑÐ¾Ð¿ÑÐ¾ÑÐ¸Ð²Ð»ÐµÐ½Ð¸Ðµ. ÐÐ·ÑÑÐµÐ½Ð° ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ñ Ð¸Ð·Ð¼ÐµÑÐµÐ½Ð¸Ñ Ð¿ÐµÑÐµÑÐ¾Ð´Ð½Ð¾Ð³Ð¾ ÑÐ¾Ð¿ÑÐ¾ÑÐ¸Ð²Ð»ÐµÐ½Ð¸Ñ.
description: The process of studying the transition resistance of a vacuum circuit breaker is presented in this work. There are the general concepts and terms related to the topic of vacuum circuit breaker. Their design, requirements and operating principle are considered. The analysis of the dependences of various characteristics that affect the transitional contact resistance is done. The technology of measuring transient resistance was studied.
A first approach to decipher the megabenthic trophic network in the Angolan cold-water coral mounds through stable isotope analysis
Creators: name: Vinha, Beatriz
name: Rossi, Sergio
name: Pennetta, Antonio
name: Gori, Andrea
name: Furu Mienis
name: Huvenne, Veerle
name: Hebbeln, Dierk
name: Wienberg, Claudia
name: Freiwald, Andre
name: Piraino, Stefano
name: Covadonga Orejas
Publisher: name: Zenodo
Year: 2021

description: The characterisation of trophic nets in the deep-sea is challenging due to the remoteness and the logistic constraints to reach and sample these habitats. Stable carbon and nitrogen isotope (δ13C and δ15N) analysis has proven to be a useful tool in identifying trophic relationships. The benthic trophic network of the fauna in the recently discovered Angolan cold-water coral (CWC) mounds is being investigated through carbon and nitrogen isotopic characterization. Samples were collected in 2016 during the M122 ("ANNA") expedition on board the R/V METEOR. Organisms belonging to different functional groups of Porifera, Cnidaria, Mollusca, Annelida, Bryozoa, Arthropoda, Echinodermata, and Chordata, as well as potential food sources (suspended particulate organic matter and organic matter of sediments) were analysed. The main aims of the study are: (1) to describe the megabenthic trophic guilds of the Angolan CWC mounds, (2) to estimate the total number of trophic levels, and (3) to compare this unexplored area with previous results from other CWC dominated communities. Our first results show that particulate organic matter presented a marine signature (δ13C from -20 to -25‰ V.P.D.B.). However, the analysed CWC species seem to prefer a diet which combined a mix of detrital and resuspended organic matter (δ13C from -15 to -20‰ V.P.D.B.), similar to what has been observed for Antarctic gorgonians and other CWC habitats. Porifera presented the highest δ15N ratios (20.19±1.81‰). We hypothesise this could be due to the assimilation of bacterioplankton as a food source which has been already documented for Porifera.
Выклікі і практыкі ўніверсітэцкіх бібліятэк. Што змянілася падчас пандэміі? / Challenges and Practices of University Libraries. What has changed during the pandemic?
Creators: name: Бруй, Оксана Николаевна
Publisher: name: Zenodo
Year: 2020
Subjects: университетские библиотеки
глобальные тренды
цифровизация
образование
открытые образовательные ресурсы
научные коммуникации
открытая наука
инновации
неформальное образование
информационное обслуживание
информационные технологии
издательская деятельность
научная деятельность
культурные проекты
дистанционная работа
корпоративное взаимодействие
онлайн-сервисы
open educational resources
open science

description: Доклад освещает вопросы, касающиеся влияния мировых тенденций на университетские библиотеки, обозначает проблемы, стоящие перед университетскими библиотеками, и способы реагирования на них, а также изменения в работе библиотек во время пандемии. Даклад асвятляе пытанні, якія тычацца ўплыву сусветных тэндэнцый на універсітэцкія бібліятэкі, пазначае праблемы, якія стаяць перад бібліятэкамі, і спосабы рэагавання на іх, а таксама змены ў рабоце бібліятэк падчас пандэміі. The report highlights issues related to the impact of global trends on university libraries, outlines the challenges facing libraries and how they respond to them, as well as changes in library work during the pandemic.
title: Avian predators as a biological control system of common vole (Microtus arvalis) populations in NW Spain: experimental set-up and preliminary results
Creators: name: Jareño, D.
name: Paz, A.
name: Arroyo, L.
name: Viñuela, J.
name: Arroyo, B.E.
name: Mougeot, F.
name: Luque-Larena, J.J
name: Fargallo, J.A.
Publisher: name: Julius Kühn-Institut
Year: 2011
Subjects: subject: Microtus arvalis
subject: outbreaks
subject: biological control
subject: Falco tinnunculus
subject: Tyto alba
subject: agriculture
subject: Spain

description: Julius-Kühn-Archiv; 432; 157-158
Compton degradation of gamma-ray line emission from radioactive isotopes in the classical nova V2491 Cygni
Creators: name: Suzuki, Akihiro
name: Shigeyama, Toshikazu
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: To account for the non-thermal emission from the classical nova V2491 Cygni, we perform a series of numerical calculations of radiative transfer of γ-ray photons from the radioactive isotope $^{22}$Na in the matter ejected from a white dwarf. Using a simple wind model for the dynamical evolution of the ejecta and a monte-carlo code, we calculate radiative transfer of the γ-ray photons in the ejecta. Repeated scattering of the γ-ray photons by electrons in the ejecta, i.e., Compton degradation, results in an extremely flat spectrum in the hard X-ray range, which successfully reproduces the observed spectrum of the X-ray emission from V2491 Cygni. The amount of the isotope $^{22}$Na synthesized in the ejecta is required to be 3\times 10^{-5} M_\odot to account for the flux of the hard X-ray emission. Our model indicates that the ejecta become transparent to the γ-ray photons within several tens days. Using the results, we briefly discuss the detectability of the γ-ray line emission by the {\it INTEGRAL} gamma-ray observatory and the {\it Fermi} Gamma-ray Space Telescope.
description: 5 pages, 4 figures, to appear in ApJL
Health and economic impact of the 13-valent pneumococcal conjugate vaccination program in British Columbia, Canada
Creators: name: Vadlamudi, Nirma Khatri
Publisher: name: University of British Columbia
Year: 2023

description: BACKGROUND: Streptococcus pneumoniae causes substantial health and economic burden. Two vaccines available to combat pneumococcal disease are the 23-valent pneumococcal polysaccharide vaccine (PPV23) for adults and the 13-valent pneumococcal conjugate vaccine (PCV13) for children. This thesis evaluated changes in health and economic burden from pneumococcal disease following the PCV13 introduction in the infant immunization program in British Columbia (BC), Canada. METHODS: A literature search and meta-analyses determined the indirect effect of the PCV13 childhood immunization on invasive pneumococcal disease (IPD) among adults worldwide. Then, pneumococcal disease, i.e., IPD, and acute otitis media (AOM), acute sinusitis (AS), and community-acquired pneumonia (CAP) cases and associated healthcare costs were identified using administrative databases for the years 2000-2018. Costs were adjusted to 2018 Canadian dollars. Changes in the incidence, annual healthcare utilization, and associated costs for pneumococcal disease were evaluated across vaccine eras (pre-PCV13 era: 2000-2010, PCV13 era: 2011-2018) using generalized linear models and adjusted for the PCV7 program (2004-2010). RESULTS: A substantial decline in overall IPD (18%), PCV7 (55%), and PCV13 (40%) serotype IPD were observed among adults following the PCV13 vaccine use in the infant immunization program globally. However, a concurrent 112% increase in non-vaccine serotype IPD occurred during the PCV13 period. Similar declines in overall IPD (18%), PCV7-related (70%), and PCV13-related (24%) vaccine serotype IPD among adults and increase in non-vaccine serotype (NVT) IPD (154%) were noted in BC. A substantial rate reduction in AOM (30%) and AS (15%) across all ages was recorded. Although CAP incidence decreased among young children aged 0-2 years (9%), there was a modest increase in the older age groups: 50-64 years (7%), and ≥65 years (5%). As such, temporal declines in total annual cost were observed in the PCV13 era for IPD (27%), AOM (30%), and AS (32%) compared to the pre-PCV13 era, but not CAP, where an increase of 4% in total costs was seen across all ages. CONCLUSIONS: Increasing NVT IPD and pneumonia rates in the post-PCV13 necessitates a need for newer vaccines and stresses the importance of improving public health messaging to increase the PPV23 uptake rates.
Higher dimensional conformal field theories in the Coulomb branch
Creators: name: Hoyos-Badajoz, Carlos
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We use the AdS/CFT correspondence to study flows of N=4 SYM to non-conformal theories. The dual geometries can be seen as sourced by a Wigner's semicircle distribution of D3 branes. We consider two cases, the first case corresponds to a point in the Coulomb branch and the theory flows to a six dimensional conformal field theory. In the second case a mass is introduced for a hypermultiplet and the theory flows to a five dimensional conformal field theory. We argue from the gravity and the field theory side that the low energy theories correspond to the (2,0) theory in six dimensions and to a theory with exceptional global symmetry $E_1$ in five dimensions.
description: 7 pages
Scaling theory of the Mott transition and breakdown of the Grüneisen scaling near a finite-temperature critical end point
Creators: name: Bartosch, Lorenz
name: de Souza, Mariano
name: Lang, Michael
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We discuss a scaling theory of the lattice response in the vicinity of a finite-temperature critical end point. The thermal expansivity is shown to be more singular than the specific heat such that the Grüneisen ratio diverges as the critical point is approached, except for its immediate vicinity. More generally, we express the thermal expansivity in terms of a scaling function which we explicitly evaluate for the two-dimensional Ising universality class. Recent thermal expansivity measurements on the layered organic conductor kappa-(BEDT-TTF)_2 X close to the Mott transition are well described by our theory.
description: 4 REVTeX pages, 4 figures; minor changes, as published
title: Ð¡Ð¾Ð·Ð´Ð°Ð½Ð¸Ðµ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð´Ð»Ñ ÑÐ°ÑÑÐ¸ÑÑÐ¾Ð²ÐºÐ¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¿Ð¾ Ð¾Ð±Ð½Ð°ÑÑÐ¶ÐµÐ½Ð¸Ñ ÑÐµÐ¿Ð»Ð¾Ð²ÑÑ Ð°Ð½Ð¾Ð¼Ð°Ð»Ð¸Ð¹ ÑÐµÐ¿Ð»Ð¾Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¾Ð²
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Creation of an automated application for decoding diagnostic results on detection of thermal anomalies of heat pipelines
Creators: name: ÐÐ¸Ð²Ð¾Ð²Ð°ÑÐ¾Ð², ÐÐ½Ð´ÑÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: ÑÐµÐ¿Ð»Ð¾Ð²Ð°Ñ Ð°Ð½Ð¾Ð¼Ð°Ð»Ð¸Ñ
ÑÐµÐ¿Ð»Ð¾Ð²Ð°Ñ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ°
PHP
MySQL
Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ðµ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ð¹
Ð±Ð°Ð·Ñ Ð´Ð°Ð½Ð½ÑÑ
a thermal anomaly
thermal diagnostics
software
databases

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð¾ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ Ð´Ð»Ñ ÑÐ°ÑÑÐ¸ÑÑÐ¾Ð²ÐºÐ¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¿Ð¾ Ð¾Ð±Ð½Ð°ÑÑÐ¶ÐµÐ½Ð¸Ñ ÑÐµÐ¿Ð»Ð¾Ð²ÑÑ Ð°Ð½Ð¾Ð¼Ð°Ð»Ð¸Ð¹ ÑÑÑÐ±Ð¾Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¾Ð². ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ ÑÐ¸Ð¿Ñ ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÐ½ÑÑ Ð°Ð½Ð¾Ð¼Ð°Ð»Ð¸Ð¹, Ð¾Ð¿Ð¸ÑÐ°Ð½Ð° Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ° Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð¹ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¾ ÑÐµÑÐ½Ð¸ÐºÐ¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ðµ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ Ð´Ð»Ñ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð¹ Ð´Ð¸Ð°Ð³Ð½Ð¾ÑÑÐ¸ÐºÐ¸ Ð¿Ð¾ Ð¾Ð±Ð½Ð°ÑÑÐ¶ÐµÐ½Ð¸Ñ Ð°Ð½Ð¾Ð¼Ð°Ð»Ð¸Ð¹ ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð¹ ÑÐµÑÐ¸, Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾, Ð²Ð½ÐµÐ´ÑÐ¸ÑÑ Ð½Ð° Ð¿ÑÐ°ÐºÑÐ¸ÐºÐµ, ÑÑÐ¾ Ð¿Ð¾Ð·Ð²Ð¾Ð»Ð¸Ñ ÑÐ·Ð½Ð°ÑÑ ÑÐ¾ÑÑÐ¾ÑÐ½Ð¸Ðµ ÑÑÑÐ±Ð¾Ð¿ÑÐ¾Ð²Ð¾Ð´Ð° Ð±ÐµÐ· Ð²ÑÐºÑÑÑÐ¸Ñ ÐºÐ°Ð½Ð°Ð»Ð° Ð¸ Ð½Ð°ÑÑÑÐµÐ½Ð¸Ñ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸.
description: In this paper, we developed an automated application for decoding the diagnostic results for the detection of thermal anomalies of pipelines. The types of temperature anomalies are determined, the technique of thermal diagnostics is described, a feasibility study is carried out. Developed an application for carrying out thermal diagnostics for the detection of thermal anomalies network may implement that will allow you to know the status of the pipeline without opening the channel and disturbance of the structure.
Dynamics of Entanglement and Bell-nonlocality for Two Stochastic Qubits with Dipole-Dipole Interaction
Creators: name: Altintas, Ferdi
name: Eryigit, Resul
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We have studied the analytical dynamics of Bell nonlocality as measured by CHSH inequality and entanglement as measured by concurrence for two noisy qubits that have dipole-dipole interaction. The nonlocal entanglement created by the dipole-dipole interaction is found to be protected from sudden death for certain initial states.
Search for Quark Compositeness with the Dijet Centrality Ratio in pp Collisions at sqrt(s)=7 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for quark compositeness in the form of quark contact interactions, based on hadronic jet pairs (dijets) produced in proton-proton collisions at sqrt(s)=7 TeV, is described. The data sample of the study corresponds to an integrated luminosity of 2.9 inverse picobarns collected with the CMS detector at the LHC. The dijet centrality ratio, which quantifies the angular distribution of the dijets, is measured as a function of the invariant mass of the dijet system and is found to agree with the predictions of the Standard Model. A statistical analysis of the data provides a lower limit on the energy scale of quark contact interactions. The sensitivity of the analysis is such that the expected limit is 2.9 TeV; because the observed value of the centrality ratio at high invariant mass is below the expectation, the observed limit is 4.0 TeV at the 95% confidence level.
Exceptional 20th century shifts in deep-sea ecosystems are spatially heterogeneous and associated with local surface ocean variability
Creators: name: O'Brien, Charlotte L.
name: Spooner, Peter T.
name: Wharton, Jack Hudak
name: Papachristopoulou, Eirini
name: Dutton, Nicolas
name: Fairman, David
name: Garratt, Rebecca
name: Tianying Li
name: Pallottino, Francesco
name: Stringer, Fiona
name: Thornalley, David J.R.
Publisher: name: Zenodo
Year: 2021

description: Traditionally, deep-sea ecosystems have been considered to be insulated from the effects of modern climate change, but with the recognition of the importance of food supply from the surface ocean and deep-sea currents to sustaining these systems, the potential for rapid response of benthic systems to climate change is gaining increasing attention. However, very few ecological time-series exist for the deep ocean covering the twentieth century. Benthic responses to past climate change have been well-documented using marine sediment cores on glacial-interglacial timescales, and ocean sediments have also begun to reveal that planktic species assemblages are already being influenced by global warming. Here, we use benthic foraminifera found in mid-latitude and subpolar North Atlantic sediment cores to show that, in locations beneath areas of major surface water change, benthic ecosystems have also changed significantly over the last ~150 years. The maximum benthic response occurs in areas which have seen large changes in surface circulation, temperature and/or productivity. We infer that the observed surface-deep ocean coupling is due to changes in the supply of organic matter exported from the surface ocean and delivered to the seafloor. The local-to-regional scale nature of these changes highlights that accurate projections of changes in deep-sea ecosystems will require (1) increased spatial coverage of deep-sea proxy records and, (2) models capable of adequately resolving these relatively small-scale oceanographic features.
Experimental Evidence of Quantum Randomness Incomputability
Creators: name: Calude, Cristian S.
name: Dinneen, Michael J.
name: Dumitrescu, Monica
name: Svozil, Karl
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: Computational Complexity (cs.CC)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: In contrast with software-generated randomness (called pseudo-randomness), quantum randomness is provable incomputable, i.e.\ it is not exactly reproducible by any algorithm. We provide experimental evidence of incomputability --- an asymptotic property --- of quantum randomness by performing finite tests of randomness inspired by algorithmic information theory.
description: 23 pages, 5 figures, statistical analysis added, other sections greatly expanded
title: Smell you later - the repelling effect of secondary plant compounds against water voles and common voles
Creators: name: Fischer, D.
name: Prokop, A.
name: Wink, M.
name: Mattes, H.
name: Jacob, J.
Publisher: name: Julius Kühn-Institut
Year: 2011

description: Julius-Kühn-Archiv; 432; 159
Molecular insights in repurposing selective COX-2 inhibitor celecoxib against matrix metalloproteinases in potentiating delayed wound healing: a molecular docking and MMPB/SA based analysis of molecular dynamic simulations
Creators: name: Mude, Lavanya
name: Jupudi, Srikanth
name: Swaroop, Akey Krishna
name: Tallapaneni, Vyshnavi
name: Karri, Veera Venkata Satyanarayana Reddy
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Matrix metalloproteinases (MMPs) are proteolytic enzymes that play a role in healing, including reducing inflammation, promoting fibroblast and keratinocyte migration, and modifying scar tissue. Due to their pleiotropic functions in the wound-healing process in diabetic wounds, MMPs constitute a significant cause of delayed wound closure. COX-2 inhibitors are proven to inhibit inflammation. The present study aims to repurpose celecoxib against MMP-2, MMP-8 and MMP-9 through in silico approaches, such as molecular docking, molecular dynamics, and MMPB/SA analysis. We considered five selective COX-2 inhibitors (celecoxib, etoricoxib, lumiracoxib, rofecoxib and valdecoxib) for our study against MMPs. Based on molecular docking study and hydrogen bonding pattern, celecoxib in complex with three MMPs was further analyzed using 1 µs (1000 ns) molecular dynamics simulation and MMPB/SA techniques. These studies identified that celecoxib exhibited significant binding affinity −8.8, −7.9 and −8.3 kcal/mol, respectively, against MMP-2, MMP-8 and MMP-9. Celecoxib formed hydrogen bonding and hydrophobic (π–π) interactions with crucial substrate pocket amino acids, which may be accountable for their inhibitory nature. The MMPB/SA studies showed that electrostatic and van der Waal energy terms favoured the total free binding energy component, while polar solvation terms were highly disfavored. The in silico analysis of the secondary structures showed that the celecoxib binding conformation maintains relatively stable along the simulation trajectories. These findings provide some key clues regarding the accommodation of celecoxib in the substrate binding S1’ pocket and also provide structural insights and challenges in repurposing drugs as new MMP inhibitors with anti-inflammatory and anti-inflammatory wound-healing properties. Communicated by Ramaswamy H. Sarma
Gauged L_mu - L_tau and different Muon Neutrino and Anti-Neutrino Oscillations: MINOS and beyond
Creators: name: Heeck, Julian
name: Rodejohann, Werner
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: If a Z' gauge boson of a gauged L_mu - L_tau symmetry is very light, it is associated with a long-range leptonic force. In this case the particles in the Sun create via mixing of Z' with the Standard Model Z a flavor-dependent potential for muon neutrinos in terrestrial long-baseline experiments. The potential changes sign for anti-neutrinos and hence can lead to apparent differences in neutrino and anti-neutrino oscillations without introducing CP or CPT violation. This could for instance explain the recently found discrepancy in the survival probabilities of muon neutrinos and anti-neutrinos in the MINOS experiment. We obtain the associated parameters of gauged L_mu - L_tau required to explain this anomaly. The consequences for future long-baseline experiments and for the anomalous magnetic moment of the muon are discussed. The main feature of our explanation is that atmospheric neutrino mixing has to be non-maximal. Neutrino masses tend to be quasi-degenerate.
description: 20 pages, 7 figures. Section on current limits added
title: ÐÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¼ÐµÑÐ¾Ð´Ð¸Ðº Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÐ¸ Ð²Ð¾Ð·Ð´ÑÑÐ½ÑÑ Ð¿ÑÐ¾Ð¼ÐµÐ¶ÑÑÐºÐ¾Ð² Ð¿ÑÐ¸ Ð²Ð¾Ð·Ð´ÐµÐ¹ÑÑÐ²Ð¸Ð¸ ÑÑÐ°Ð½Ð´Ð°ÑÑÐ½ÑÐ¼ Ð³ÑÐ¾Ð·Ð¾Ð²ÑÐ¼ Ð¸Ð¼Ð¿ÑÐ»ÑÑÐ¾Ð¼
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Features of methods for assessing the dielectric strength of air gaps when exposed to a standard lightning impulse
Creators: name: ÐÐ¾ÑÐ¾Ð²Ð¸ÐºÐ¾Ð², ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: Ð­Ð»ÐµÐºÑÑÐ¾Ð¸Ð·Ð¾Ð»ÑÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ
Ð­Ð»ÐµÐºÑÑÐ¾Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ
Ð²Ð¾Ð»ÑÑ-ÑÐµÐºÑÐ½Ð´Ð½Ð°Ñ Ñ Ð°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ°
ÑÑÐ°Ð½Ð´Ð°ÑÑÐ½ÑÐ¹ Ð³ÑÐ¾Ð·Ð¾Ð²Ð¾Ð¹ Ð¸Ð¼Ð¿ÑÐ»ÑÑ
olt-second characteristic
standard thunderstorm pulse

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð½ÐµÑÐºÐ¾Ð»ÑÐºÐ¾ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÐ¸ Ð²Ð¾Ð·Ð´ÑÑÐ½ÑÑ Ð¿ÑÐ¾Ð¼ÐµÐ¶ÑÑÐºÐ¾Ð², ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¿ÑÐ¸Ð¼ÐµÐ½ÑÑÑÑÑ ÑÐµÐ³Ð¾Ð´Ð½Ñ Ð² Ð¼Ð¸ÑÐµ, Ð½Ð¾ Ð² ÑÐ¿ÑÐ¾ÑÐµÐ½Ð½Ð¾Ð¼ Ð²Ð¸Ð´Ðµ, ÑÐ°Ðº ÐºÐ°Ðº Ð´Ð»Ñ Ð±Ð¾Ð»ÐµÐµ Ð³Ð»ÑÐ±Ð¾ÐºÐ¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð½ÑÐ¶Ð½Ð¾ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑ Ð¼Ð½Ð¾Ð¶ÐµÑÑÐ²Ð¾ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ¾Ð². Ð Ð¿ÐµÑÐ²Ð¾Ð¹ ÑÐ°ÑÑÐ¸ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐ¸Ð²ÐµÐ´ÐµÐ½ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐ½ÑÐ¹ Ð¾Ð±Ð·Ð¾Ñ ÑÑÐ´Ð° Ð¸ÑÑÐ¾ÑÐ½Ð¸ÐºÐ¾Ð² Ñ ÑÐµÐ»ÑÑ Ð²ÑÑÐ²Ð»ÐµÐ½Ð¸Ñ Ð°ÐºÑÑÐ°Ð»ÑÐ½Ð¾ÑÑÐ¸ Ð´Ð°Ð½Ð½Ð¾Ð¹ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ ÑÐ°Ð¼Ð¸Ñ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð¾Ð² Ð¾ÑÐµÐ½ÐºÐ¸ Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÐ¸ Ð¸ÑÐºÑÐ¾Ð²ÑÑ Ð¿ÑÐ¾Ð¼ÐµÐ¶ÑÑÐºÐ¾Ð². ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¹ ÑÐ°ÑÑÐ¸ Ð¿ÑÐ¸Ð²ÐµÐ´ÐµÐ½Ð¾ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð´Ð°Ð½Ð½ÑÑ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð¾Ð² Ð´Ð»Ñ ÑÑÐ°Ð½Ð´Ð°ÑÑÐ½Ð¾Ð³Ð¾ Ð¸ Ð½ÐµÑÑÐ°Ð½Ð´Ð°ÑÑÐ½Ð¾Ð³Ð¾ Ð¸Ð¼Ð¿ÑÐ»ÑÑÐ¾Ð² Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½Ð¾Ð¹ Ð°Ð¼Ð¿Ð»Ð¸ÑÑÐ´Ð¾Ð¹.
description: In this paper, we consider several basic methods for assessing the electrical strength of air gaps that are used today in the world, but in a simplified form, since many experiments need to be carried out for a more in-depth analysis. In the first part of the work, a literature review of a number of sources is given in order to identify the relevance of this problem and to describe the approaches themselves for assessing the strength of spark gaps. The second part presents mathematical modeling of these approaches for standard and non-standard pulses with different amplitudes.