cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Insulin Resistance, Metabolic Syndrome and Diabetes in Women at High Risk for Breast Cancer
Creators: name: Dumais, Valerie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Diabetes
Insulin Resistance
Breast Cancer
Metabolic Syndrome
High Risk

description: Purpose: The overall objective of this prospective study was to quantify the prevalence of insulin resistance (IR), metabolic syndrome (MetS) and type 2 diabetes (T2D) in women at high risk for breast cancer, stratified by menopausal status. We also aimed to calculate the sample size required for a future case-control study comparing these prevalences to those of the general population. Methods: Participants consisted of 100 Caucasian women above the age of 35 with an estimated 5yr risk of breast cancer ≥1.7%. A comprehensive metabolic profile was obtained for each participant based on a questionnaire, fasting blood sample and biophysical measurements. Results: In comparison to published prevalence’s of IR, MetS and T2D in the general population, the prevalence of IR and MetS is higher in our study sample. High risk postmenopausal women have a higher prevalence of body mass index, waist circumference, MetS and hypertension than premenopausal women. We have shown a significant correlation between Gail score and high-density lipoprotein cholesterol. Conclusions: The sample size calculation, based on the prevalence’s obtained in the present study, support the significance and feasibility of a future case control study comparing the prevalence of IR and MetS in women at high risk and average risk for breast cancer. Further studies are needed to clarify the underlying mechanisms for the association between IR, MetS, T2D and breast cancer risk.
Supplementary document for Characterization of a chromatic confocal displacement sensor integrated with an optical laser head - 5146256.pdf
Creators: name: Zakrzewski, Adrian
name: Jurewicz, Piotr
name: Koruba, Piotr
name: Cwikla, Michal
name: Reiner, Jacek
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Surface parameters of selected materials.
La argumentación en los ensayos de William Ospina
Creators: name: Peralta-Sánchez, Andrés-Felipe
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: William Ospina, Argumentation, Essay (Literary Genre), Latin American Literature, Colombian Literature

description: This thesis analyzes the political essays of critically-acclaimed and best-selling Colombian author William Ospina (b. March 2, 1954) within the context of the contemporary political Spanish American essays published post 1989. Taking into account his original Romantic answer to the Spanish American left ideological crisis at the end of the 20th century, and the debate which arose among his commentators on the merits of his rhetorical and argumentative techniques used to justify his theses, I examine Ospina´s main political essays using Belgian philosopher Chaïm Perelman's argumentation theory. I claim that, despite his prominence as one of Colombia´s public opinion leaders and most politically engaged intellectuals, his originality within recent Spanish American essay and thought, and the relevance of his warnings against modern society's biggest problems and contradictions, the author’s controversial rhetoric and argumentation fell short of supporting his critique of Western civilization and promoting his Romantic alternatives to current problems. I also claim that Ospina's preference for certain argumentative devices results in literary texts which struggle between the essay and the pamphlet, and oversimplifies the Romantic ideas he tries to defend. Finally, my work has allowed me to point out the lack of academic studies and concrete textual analysis on Ospina´s essays and literary works, the recent Spanish American essay after 1989, and the study of the Spanish American essay’s argumentative purpose, structure and techniques, making this study a first step in the further development of these fields.
The origins of the Olympic Village: Los Angeles 1932 and Berlin 1936.
Le origini del Villaggio Olimpico. Los Angeles 1932 e Berlino 1936.
Creators: name: Bortolotti, Massimo; Università Di Udine
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2009

description: Regarding the transformations produced by the housing projects for the Olympic Games, the construction and following reuse of the Olympic Villages is an interesting studying matter. During the hundred-year-old history of the modern Olympics the realization of the Olympic Village, which finds reference in the de Coubertin’s writings, and the town planning transformations, to this correlated, have revealed in different ways.
The essay mainly concerns the origins of the Olympic Village and the first settlements which characterized the Games in the thirties: Los Angeles 1932 and Berlin 1936. In these two cities, even though with different motivations, politico-economical stimulus and different images, the prototypes of the modern Olympic sport facilities, which find in the village an in the stadium the symbol of the event, were born.
description: Nell’ambito delle trasformazioni generate dagli interventi per le Olimpiadi la costruzione ed il successivo riuso dei Villaggi Olimpici costituisce un interessante caso di studi. Nella centenaria storia delle Olimpiadi moderne la realizzazione del Villaggio Olimpico, che trova riferimento negli scritti di de Coubertin, e le operazioni di trasformazione urbanistica ad esso correlate si sono manifestate in modi diversi. Lo scritto si concentra sulle origini del Villaggio Olimpico e sulle prime due realizzazioni che caratterizzano i Giochi degli anni trenta del novecento: Los Angeles 1932 e Berlino 1936. In queste due città, sia pur con motivazioni, spinte politiche, economiche ed immagini diverse, nascono i prototipi dei moderni impianti sportivi olimpici che trovano proprio nel villaggio e nello stadio il simbolo della manifestazione.
Influence of Menarche on Body Weight. A Systematic Review and Meta-Analysis.
Creators: name: Chiasson, Martine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Menarche
Weight gain
Adipose tissue
Obesity
Body fat distribution

description: It has been shown that post-menarcheal girls are more likely to have increased their body weight and body mass index (BMI) than pre-menarcheal girls of the same age. In addition to the metabolic changes which occur during this interval, behavioural risk factors synergize to promote weight gain, putting adolescents at a much higher risk for excess weight gain and its associated health complications. Moreover, obesity during adolescence increase the risk of becoming an obese adult. A systematic review of English and French articles using MEDLINE, EMBASE, Cochrane, and CINAHL was conducted. Studies underwent a three level screening assessment by two independent assessors. Only studies with post-menarcheal weight change information were selected for data extraction and quality assessment, which was conducted by two independent reviewers. A meta-analysis was conducted for weight change and included 389 girls. Five studies discussed the effects of menarche on body weight change. Pooled results for three studies indicated a 10.39 kg increase from pre to post-menarche (95% CI, 9.16-11.62). The other two studies showed significant increases in body fat mass (p<0.05) and higher skinfolds measurements for post-menarcheal girls compared to pre-menarcheal girls. It is important to further explore the bio-psychosocial and environmental factors influencing the weight, especially the total fat mass and body fat distributions in young adolescent girls during the menarche transition in order to develop and evaluate preventive intervention strategies to prevent adolescent and adult obesity.
Communication of architectural design and Prefab-houses.
Prefab-houses e comunicazione del progetto.
Creators: name: Ballabeni, Massimo; Università Di Bologna
name: Cipriani, Luca; Università Di Bologna
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2009

description: The article investigates the relationship between architecture design and its communication, within the study of the prefab-houses, which now are widespread in Europe, as this housing type is characterized by the design research of optimized and innovative residential solutions. The operational experience conducted on case studies of “Prefab-Houses”, offered original ideas because these buildings, while exceptionally compact, share many features with larger buildings. These can be studied for their aggregability, combinatorial possibilities, furniture, the materials used and development of construction details. The communication of the project and its digital representation is particularly important as retailers generally promote these houses through catalogues. Specialized visualisation systems are therfore needed to represent effectively the inner-outer spaces, materials and customizations, with different techniques such as drawings, abstract-photorealistic rendering and animation. The match between case studies and research was considered successful in terms of teaching goals and besides research directions concerning the relationship between design representation means, modeling and 3D digital design communication systems.
description: L’articolo indaga il disegno del progetto di architettura in rapporto alla sua comunicazione, attraverso lo studio di una particolare tipologia edilizia: le case prefabbricate; oggi di grande diffusione in Europa, e interessata dalla ricerca progettuale di soluzioni residenziali ottimizzate e innovative. Le esperienze operative svolte sui casi di studio delle “Prefab-Houses”, hanno offerto spunti di particolare originalità perché sono costruzioni dimensionalmente limitate, ma che presentano tutti gli aspetti di organismi più estesi. Consentono di approfondire l’aggregabilità, le possibilità combinatorie, l’arredamento, la scelta e il tipo dei materiali e per lo sviluppo dei particolari costruttivi. La comunicazione del progetto e della rappresentazione digitale è particolarmente importante perché la promozione avviene su “catalogo” e non sul “costruito”, e quindi utilizza dei sistemi di visualizzazione particolarmente efficaci per mostrare lo spazio interno-esterno, i materiali e le personalizzazioni, mediante diverse tecniche: schemi grafici, renderizzazioni astratte-fotorealistiche e animazioni. La convergenza tra casi di studio-ricerca si è rivelata particolarmente positiva sul piano dell’insegnamento, ed inoltre, emergono ulteriori indirizzi di ricerca, legati all’approfondimento del rapporto tra disegno di progetto e la modellazione tridimensionale e ai sistemi di comunicazione digitale del progetto.
Klimaschutzplan 2050 der Bundesregierung
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: subject: Klimaschutzpolitik
subject: Treibhausgasminderung
subject: Reduktion der Treibhausgasemission
subject: Treibhausgasemissionsminderung
subject: Treibhausgasreduzierung
subject: Klima | Energie
subject: Climate | Energy

description: Ziel dieses Papiers ist es, konkrete Vorschläge und aus Sicht des Umweltbundesamtes notwendige Schritte für eine nachhaltige und ambitionierte Ausgestaltung in den Prozess zur Erstellung des Klimaschutzplanes 2050 der Bundesregierung einzuspeisen. Der Fokus liegt auf der Darstellung strategischer Maßnahmen und Instrumente für den Zeitraum 2020 bis 2030, die somit unmittelbar an das Aktionsprogramm Klimaschutz 2020 der Bundesregierung anschließen. Maßstab ist dabei der obere Rand des nationalen und europäischen Zielkorridors: eine Minderung der Treibhausgasemissionen bis 2050 um 95 Prozent. Quelle: https://www.umweltbundesamt.de
description: Ziel dieses Papiers ist es, konkrete Vorschläge und aus Sicht des Umweltbundesamtes notwendige Schritte für eine nachhaltige und ambitionierte Ausgestaltung in den Prozess zur Erstellung des Klimaschutzplanes 2050 der Bundesregierung einzuspeisen. Der Fokus liegt auf der Darstellung strategischer Maßnahmen und Instrumente für den Zeitraum 2020 bis 2030, die somit unmittelbar an das Aktionsprogramm ⁠Klimaschutz⁠ 2020 der Bundesregierung anschließen. Maßstab ist dabei der obere Rand des nationalen und europäischen Zielkorridors: eine Minderung der Treibhausgasemissionen bis 2050 um 95 Prozent.
Supplementary document for Optical characterization of Y3Al5O12 and Lu3Al5O12 single crystals - 5146626.pdf
Creators: name: Hrabovsky, Jan
name: Kucera, Miroslav
name: Palousova, Lucie Lucie
name: Bi, Lei
name: Veis, Martin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Optical Properties of Materials

description: Suppl.1. Fit error analysis, Suppl.3. Two-oscillator Sellmeier model
Unstable Identity in Caryl Churchill's Love and Information
Creators: name: Gowans, Caitlin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Caryl Churchill
Logical identity
Love and Information

description: Caryl Churchill’s play, Love and Information, presents a shift in focus from unstable personal and political identity towards unstable logical identity, a philosophical concept that takes identity out of the realm of identity politics.. As a new play Love and Information has understandably been subject to very little scholarly analysis. This thesis situates the play within Churchill’s corpus in order to consider how the depersonalized identities of this play fit within the broader scope of Churchill’s work. Anchored in Elin Diamond’s study of gender identity in Churchill’s corpus, this thesis will further incorporate theories of logical identity as well as theories of language in order to define what I argue is Churchill’s shift towards logical identity. Through a study of both the text of Love and Information and the 2014 New York première, I conclude that Love and Information represents a shift in focus while Churchill maintains her playwriting methodology.
Investigation of a framework for epidemiological studies of Campylobacter jejuni based on the combination of genetic markers and MALDI-TOF MS typing schemes
Creators: name: Ahmed, Monir Uddin
Publisher: name: Swinburne
Year: 2024

description: Campylobacter jejuni is the most common foodborne bacterial pathogen responsible for a significant burden to public health worldwide. Bacterial typing schemes play an important role in the control of foodborne infections by helping source tracing and revealing the routes of transmission of pathogens. This study investigated the suitability of combinations of genetic markers based typing schemes and Matrix assisted laser desorption/ Ionization- time of flight mass spectrometry. The application of the developed framework addressed the need for more rapid, cost effective and accurate methodological approach to identify the origin and thus control C. jejuni infections.
Supplementary document for Optical characterization of Y3Al5O12 and Lu3Al5O12 single crystals - 5146626.pdf
Creators: name: Hrabovsky, Jan
name: Kucera, Miroslav
name: Palousova, Lucie Lucie
name: Bi, Lei
name: Veis, Martin
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Optical Properties of Materials

description: Suppl.1. Fit error analysis, Suppl.3. Two-oscillator Sellmeier model
The architectural plan and the moving image. Audio-visual media for the plan: to document, to present, to diffuse.
Il progetto architettonico e l’immagine in movimento. L’audiovisivo per il progetto: documentare, presentare, divulgare.
Creators: name: Gagliardi, Maria Letizia; Università Di Udine
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2009

description: The architecture needs to be communicated and to communicate, that’s why, in every period, the architect has used innovative tools which could “make public” his work. From the convention of the architectural drawing, to the prospective, photography, cinema, computer and tele-vision, architecture’s communication has found in the dynamic image the right tool for the representation of the relation between space, time and human being, a relation which implies contrasts and framings, that is a succession of images.
In this article we will identify three different ways of telling architecture through moving images, three narrations that correspond to three different techniques of planning, shooting and post-production: the documentary, the simulation and the tele-vision.
description: L’architettura ha bisogno di essere comunicata e di comunicare, per questo, in ogni epoca, l’architetto si è servito di strumenti innovativi che potessero “rendere pubblico” il proprio lavoro. Dalla convenzione del disegno architettonico, alla prospettiva, alla fotografia, al cinema, al computer, alla tele-visione, la comunicazione dell’architétura ha trovato nell’immagine dinamica, lo strumento adeguato per la rappresentazione del rapporto tra lo spazio, il tempo e l’uomo, rapporto che implica contrasti e inquadrature, ovvero una successione di immagini. In questo articolo individueremo tre diversi modi di raccontare l’architettura attraverso le immagini in movimento, tre narrazioni che equivalgono a tre diverse tecniche di progettazione, di ripresa e di post produzione: il documentario, la simulazione, la tele-visione.
Pour ou contre l'utilisation d'animaux en science? Enquête sur les représentations sociales qui informent le débat
Creators: name: Belleau, Pascale
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: utilisation d'animaux en science
représentations sociales
utilité
moralité
oppositions
émotions

description: Notre recherche porte sur le savoir de sens commun créé, partagé et utilisé par les étudiants quant à l’utilisation d’animaux en science, une pratique faisant l’objet d’un débat polarisé. Notre objectif est d’aller au-delà des attitudes individuelles qui varient selon plusieurs facteurs et d’interroger ce qui relève plus généralement du collectif. Nous avons eu recours à la théorie des représentations sociales formulée par Serge Moscovici pour répondre à notre question de recherche: « Quelles sont les représentations sociales de l’utilisation d’animaux en science chez les étudiants? ». L’approche utilisée fut qualitative et empirique. Nous avons mené deux groupes de discussion composés d’étudiants de l’Université d’Ottawa et effectué une analyse qualitative des discussions. Nos résultats montrent que les représentations partagées par ces individus sont générées par les aspects « descriptifs » de l’utilisation, son utilité et sa moralité, souvent antinomiques ou émotives et influencées par les images diffusées dans les médias.
Zur Bedeutung der Listen bekannt gemachter Mittel und Verfahren für behördlich angeordnete Entseuchungen, Entwesungen und zur Bekämpfung von Wirbeltieren auf Grundlage des § 18 Infektionsschutzgesetz
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2014
Subjects: Desinfektion
Entwesung
Schädlingsbekämpfung

description: Zum Schutz des Menschen vor übertragbaren Krankheiten dürfen bei behördlich angeordneten Entseuchungen (Desinfektion), Entwesungen (Bekämpfung von Gliedertieren) und Maßnahmen zur Bekämpfung von Wirbeltieren, durch die Krankheitserreger verbreitet werden können, nur Mittel und Verfahren verwendet werden, die von der zuständigen Bundesoberbehörde in einer Liste im Bundesgesundheitsblatt bekannt gemacht worden sind. Die Aufnahme in die Liste erfolgt nur, wenn die Mittel und Verfahren hinreichend wirksam sind und keine unvertretbaren Auswirkungen auf Gesundheit und Umwelt haben (§ 18 IFSG). Für Hersteller von Desinfektionsmitteln und Schädlingsbekämpfungsmitteln besteht keine Verpflichtung, ihre Präparate in die Listen nach § 18 IfSG eintragen zu lassen. Insbesondere ist die Eintragung in die Listen keine Voraussetzung für den Marktzugang in Deutschland. Dem Anwender steht die Wahl des Mittels grundsätzlich frei, soweit es sich nicht um behördlich angeordnete Maßnahmen, d. h. Entseuchungen, Entwesungen oder Maßnahmen gegen Wirbeltiere gemäß § 17 IfSG handelt. Es ist jedoch dringend zu empfehlen, auch bei routinemäßiger Anwendung die oben genannten Listen zu Rate zu ziehen, da bei den dort aufgeführten Mitteln und Verfahren die Wirksamkeit durch behördliche, teilweise im Rahmen von Akkreditierungen qualitätsgesicherten Prüfungen oder Sachverständigengutachten belegt und von unabhängigen Institutionen bestätigt wurde.
© www.link.springer.com
Barriers and facilitators to the implementation of brief interventions targeting smoking, nutrition, and physical activity for indigenous populations: a narrative review
Creators: name: Fazelipour, Mojan
name: Cunningham, Frances
Publisher: name: BioMed Central
Year: 2019

description: Objective: This narrative review aimed to identify and categorize the barriers and facilitators to the provision of brief intervention and behavioral change programs that target several risk behaviors among the Indigenous populations of Australia, Canada, and New Zealand. Methods: A systematic database search was conducted of six databases including PubMeD, Embase, CINAHL, HealthStar, PsycINFO, and Web of Science. Thematic analysis was utilized to analyze qualitative data extracted from the included studies, and a narrative approach was employed to synthesize the common themes that emerged. The quality of studies was assessed in accordance with the Joanna Briggs Institute’s guidelines and using the software SUMARI – The System for the Unified Management, Assessment and Review of Information. Results: Nine studies were included. The studies were classified at three intervention levels: (1) individual-based brief interventions, (2) family-based interventions, and (3) community-based-interventions. Across the studies, selection of the intervention level was associated with Indigenous priorities and preferences, and approaches with Indigenous collaboration were supported. Barriers and facilitators were grouped under four major categories representing the common themes: (1) characteristics of design, development, and delivery, (2) patient/provider relationship, (3) environmental factors, and (4) organizational capacity and workplace-related factors. Several sub-themes also emerged under the above-mentioned categories including level of intervention, Indigenous leadership and participation, cultural appropriateness, social and economic barriers, and design elements. Conclusion: To improve the effectiveness of multiple health behavior change interventions among Indigenous populations, collaborative approaches that target different intervention levels are beneficial. Further research to bridge the knowledge gap in this topic will help to improve the quality of preventive health strategies to achieve better outcomes at all levels, and will improve intervention implementation from development and delivery fidelity, to acceptability and sustainability.
Parestesias misteriosas: trastorno orgánico vs síndrome conversivo
Creators: name: Ríos Vaquero, María
name: Lorenzo Chapatte, Gloria
name: Rojas Vázquez, Lorenzo
name: Monllor Lazarraga, Alfonso
name: Jiménez Aparicio, Teresa
name: Sobrino Conde, Luis
Publisher: name: Zenodo
Year: 2024

description: INTRODUCCIÓN Y OBJETIVOS

Se presenta un caso en el que se expone la dificultad del abordaje clínico a la hora de filiar episodios con sintomatología de posible etiología diferente frente a la categorización teórica de los mismos.

DESCRIPCIÓN DEL CASO

Se expone el caso de una mujer de 26 años de edad, de origen extranjero que visita en repetidas ocasiones en el servicio de urgencias por presentar episodios sincopales y alteración en la sensibilidad en hemicuerpo y hemicara izquierdos que tras estudio por neurología impresiona de posible síndrome conversivo. Sin embargo al realizar historia completa en las sucesivas visitas se detallaron otros posibles factores de interés como síndrome de churg Strauss del padre, epilepsia y valvulopatía mitral en hermana gemela y sintomatología depresiva en su madre. Se le cita para realización de varias pruebas complementarias a las que la paciente no acude, lo que llama la atención.

EXPLORACIÓN Y PRUEBAS COMPLEMENTARIAS:

-RMN cerebral: Cisterna Magna Vs quiste aracnoideo retrocerebeloso. Nódulos subependimarios múltiples.

-RMN cervical sin hallazgos reseñables.

-RMN dorsolumbar, EEG y holter: no acude.

DIAGNÓSTICO DIFERENCIAL Y TRATAMIENTO

En este caso planteamos realizar el diagnóstico diferencial con diferentes patologías que también cursan con misma sintomatología como el sd. Churg Strauss, compresión vertebral de raíces nerviosas o causa funcional. Se realiza seguimiento en consultas de neurocirugía y de psiquiatría realizando tratamiento con escitalopram y alprazolam con ligera mejoría. Además realiza psicoterapia.

DISCUSIÓN Y CONCLUSIONES

En este caso no queda claro la presencia de patología orgánica dada la poca colaboración a la hora de realizar pruebas complementarias. Si bien esto apoya la impresión de ser de causa funcional o simulada. Revisando la literatura científica en algunos casos es dificultoso esclarecer la etiología del cuadro y se debe tener en cuenta una visión multidisciplinar abordando el caso en su conjunto.
Eighth Annual Conference of inVIVO Planetary Health: From Challenges to Opportunities
Creators: name: Prescott, Susan L.
name: Hancock, Trevor
name: Bland, Jeffrey
name: Bosch, Matilda Van Den
name: Jansson, Janet K.
name: Johnson, Christine C.
name: Kondo, Michelle
name: Katz, David
name: Kort, Remco
name: Kozyrskyj, Anita L.
name: Logan, Alan C.
name: Lowry, Christopher A.
name: Nanan, Ralph
name: Poland, Blake
name: Robinson, Jake
name: Schroeck, Nicholas
name: Sinkkonen, Aki
name: Springmann, Marco
name: Wright, Robert O.
name: Wegienka, Ganesa
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: inVIVO Planetary Health (inVIVO) is a progressive scientific movement providing evidence, advocacy, and inspiration to align the interests and vitality of people, place, and planet. Our goal is to transform personal and planetary health through awareness, attitudes, and actions, and a deeper understanding of how all systems are interconnected and interdependent. Here, we present the abstracts and proceedings of our 8th annual conference, held in Detroit, Michigan in May 2019, themed “From Challenges, to Opportunities”. Our far-ranging discussions addressed the complex interdependent ecological challenges of advancing global urbanization, including the biopsychosocial interactions in our living environment on physical, mental, and spiritual wellbeing, together with the wider community and societal factors that govern these. We had a strong solutions focus, with diverse strategies spanning from urban-greening and renewal, nature-relatedness, nutritional ecology, planetary diets, and microbiome rewilding, through to initiatives for promoting resilience, positive emotional assets, traditional cultural narratives, creativity, art projects for personal and community health, and exploring ways of positively shifting mindsets and value systems. Our cross-sectoral agenda underscored the importance and global impact of local initiatives everywhere by contributing to new normative values as part of a global interconnected grass-roots movement for planetary health.
Are circulating tumor cells (CTCs) ready for clinical use in breast cancer? An overview of completed and ongoing trials using CTCs for clinical treatment decisions
Creators: name: Schochter, Fabienne
name: Friedl, Thomas
name: De Gregorio, Amelie
name: Krause, Sabrina
name: Huober, Jens
name: Rack, Brigitte K.
name: Janni, Wolfgang
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Circulating tumor cells (CTCs)
subject: Breast cancer
subject: CTC-based treatment decisions
subject: DDC 610 / Medicine & health
subject: Neoplastic cells, Circulating
subject: Clinical trial
subject: Breast neoplasms
subject: Klinisches Experiment
subject: Brustkrebs

description: In recent years, breast cancer treatment has become increasingly individualized. Circulating tumor cells (CTCs) have the potential to move personalized medicine another step forward. The prognostic relevance of CTCs has already been proven both in early and metastatic breast cancer. In addition, there is evidence that changes in CTC numbers during the course of therapy can predict treatment response. Thus, CTCs are a suitable tool for repeated treatment monitoring through noninvasive liquid biopsy. The next step is to evaluate how this information can be used for clinical decision making with regard to the extension, modification, or abandonment of a treatment regimen. This review will summarize the completed and ongoing clinical trials using CTC number or phenotype for treatment decisions. Based on current knowledge, CTCs can be regarded as a useful prognostic and predictive marker that is well suited for both risk stratification and treatment monitoring in breast cancer patients. However, there is still the need to provide su cient and unequivocal evidence for whether CTCs may indeed be used to guide treatment decisions in everyday clinical practice. The results of the ongoing trials described in this review are eagerly awaited to answer these important questions.
The Rialto Bridge in Venice. Reconstruction of Andrea Palladio’s project by a “capriccio” of Canaletto.
Il ponte di Rialto a Venezia. Ricostruzione del progetto di Andrea Palladio da un “capriccio” di Canaletto.
Creators: name: Ersetig, Diego; Università Di Udine
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2009

description: This study analyzes the architectonic “capriccio” built by Canaletto in 1742: Rialto with project of Andrea Palladio and other palladian buildings.
The research investigates the painting about the perspective representation and the threedimensional reconstruction of the second project of 1569 by Andrea Palladio for the Rialto bridge in Venice. This architectural concept was never realized and appears to be the main theme of the work of Canaletto.
This “capriccio” can be regarded as one of the first architectural photomontages of the history.
description: Lo studio in oggetto analizza il “capriccio” architettonico realizzato dal Canaletto nel 1742: Rialto con il progetto di Palladio e altri edifici palladiani. L’indagine riguarda la raffigurazione dal punto di vista prospettico e la ricostruzione tridimensionale del secondo progetto di Andrea Palladio del 1569 per il ponte di Rialto a Venezia, mai realizzato e figura centrale dell’opera del Canaletto. Il capriccio può essere considerato come uno dei primi fotomontaggi di progetto architettonico della storia.
Mineralogy, petrology and petrogenesis of syenitic rocks of the Porcupine-Destor fault zone near Matheson, Ontario
Creators: name: Pigeon, Luc
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Geology.
subject: Mineralogy.

description: The mineralogy, petrology and petrogenesis of a representative suite of late Archean syenitic intrusions emplaced along the Porcupine-Destor fault zone near Matheson, Ontario in the southern Abitibi greenstone belt are studied using a combined approach involving field work, petrography, mineral chemistry and, major and trace element geochemistry. Members of the Matheson suite are from east to west: Iris, Garrison, Emens, Ludgate and Pangea intrusions. The Iris, Emens, Ludgate and Pangea intrusions are mostly composed of syenitic rocks with compositions ranging from alkali-feldspar quartz-syenite to melasyenite. Textures range from equigranular to porphyritic. Iris and Pangea intrusions also contain related mafic rocks. The Garrison intrusion is composed of hornblende quartz-monzonite. All intrusions but one have hypersolvus feldspar assemblages; the exception being Garrison intrusion, which displays a subsolvus feldspar assemblage. The occurrence of late aegirine-augite, magnesioriebeckite and widespread albite replacement, especially in rocks from Ludgate and Iris intrusions, indicates that late or post-magmatic sodium-rich fluids variably affected the rocks. Two magmatic series were identified based on silica-saturation properties and alkali-contents. (Abstract shortened by UMI.)
Northeast fish. Something like tracing straight lines.
Un pesce a nordest. In fin dei conti si tratta di tracciare linee dritte.
Creators: name: Florian, Christian; Università Di Udine
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2009

description: This article/interview with Marzio Perin (Permasteelisa Group) investigates the cause-effect relations between the adoption of cutting-edge digital tools and the positive achievements in design, project management and construction of architectural envelopes complex geometries. It is the case, for example, of the Gehry Partners Barcelona Olympic Fish, first “digital project” of the american firm and first of several collaborations with the Permasteelisa group, world leader in Curtain wall projects. The article discusses the various aspects of the construction of a complex envelope: from design coordination, to production, installation and maintenance.
description: L’articolo/intervista a Marzio Perin (Permasteelisa Group) indaga il rapporto di causa effetto tra l’adozione di strumenti digitali all’avanguardia e il successo nel progetto, gestione e realizzazione di involucri architettonici geometricamente complessi. È il caso, ad esempio, del Barcelona Olympic Fish di Gehry Partners, primo “progetto digitale” della firma americana e prima di una serie di collaborazioni con il gruppo italiano leader mondiale nel curtain wall. L’articolo affronta i diversi aspetti della realizzazione di un involucro architettonico complesso, dalla progettazione digitale e il coordinamento, alla produzione, messa in opera e manutenzione.
Biomechanical analysis of two methods of descending stairs
Creators: name: Beaulieu, Francois G. D
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Health Sciences, Recreation.

description: The activity of descending stairs increases loading at the joints of the lower extremities (Andriacchi et al., 1980) as compared to walking (McFadyen and Winter, 1988), which may cause certain discomfort and or difficulties in completing the task. This study compared and contrasted the kinematics and kinetics of forward and backward stair descent to Winter's level walking (1991). We compared the support moments and moment powers of the lower limb joints while descending stairs and secondly, performed an analysis of the position of the foot on the step (ground reaction forces) to determine which method was more likely to reduce the risk of slipping. Larger double peak support moments with reduced ankle plantar flexor and increased knee extensor moments were found. The hip moments were relatively small and highly variable. There was a significantly reduced peak knee extensor eccentric power (P = 0.005) with backwards descent. These results demonstrate that stair descent (forward and backward) required higher moments at the knee than level walking but backward descent demanded less peak knee moment and eccentric power than forward descent. Overall, the use of a backward approach, offer an alternative for people unable to access stairs in the forward fashion. (Abstract shortened by UMI.)
Smarte Geräte: schnell unbrauchbar dank Software
Creators: name: Köhn, Marina
name: Pospesch, Jonas
Publisher: name: My University
Year: 2023

description: Egal ob Kaffeemaschinen, Fernseher oder E-Bikes: Immer mehr Geräte sind nicht nur digital, sondern auch online. Das kann teure Folgen haben. © rbb
Models of urban development in XVII sec. Bologna. San Luca and Alemanni porticos. Surveying and drawing.
Modelli di evoluzione urbana: addizioni seicentesche a Bologna. Rilievi e disegni dei portici di San Luca e degli Alemanni.
Creators: name: Ballabeni, Massimo; Università Di Bologna
name: Cipriani, Luca; Università Di Bologna
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2009

description: The aim of the study is to re-discover the suburban arcades of the XVII and XVIII century in Bologna, as they were always considered independent elements rather than elements guiding the development of the city. Their evolution model returns an interpretative key for today’s urban development design.  These urban structures formed outside the city walls during the eighteenth and seventeenth century. The two arcades connected the places where the ramparts stood to the Sanctuary of San Luca and to the church of Santa Maria Lacrimosa of Alemanni. The Alemanni Portico is today recognizable only visually, as it is surrounded by urban blocks. While the hill side of San Luca Portico , which was completed much later with the arcade of Meloncello, remains a strong and distinct sign welcoming people entering Bologna from North and West. Within this research, the city is studied by surveying, drawings and photographs, so as to return its representation. The graphic processing completes the conceptual and analytical framework and demonstrates the connection between reading and project, and therefore, it can be considered as useful mean of analysis and intervention on the existing city.
description: L’obiettivo dello studio è indagare i sistemi porticati extraurbani del XVII e XVIII secolo di Bologna e il loro sviluppo. L’interpretazione del loro modello di crescita fornisce una chiave di lettura importante dei modi di progettare lo sviluppo urbano nel nostro tempo. Queste architetture da sempre considerate elementi “autonomi”, sono invece elementi “ordinatori” dello sviluppo della città. Caratteristica dello sviluppo bolognese è data dai marcati segni al di fuori della cinta muraria urbana formatisi nel corso di Seicento e Settecento. Le strutture porticate esaminate collegano i luoghi dove sorgevano i bastioni al Santuario di San Luca e alla chiesa di Santa Maria Lacrimosa degli Alemanni. Oggi il portico degli Alemanni è riconoscibile solo visivamente perché inglobato nel tessuto urbano. Al contrario, il portico di San Luca, sviluppato sulla collina e terminato più tardi con la costruzione dell’arco del Meloncello, è un segno marcato che accoglie chi arriva a Bologna da Nord e da Ovest. Con il presente studio, la città esistente è indagata per mezzo di rilievi, disegni e fotografie che ne restituiscono la rappresentazione. Successive elaborazioni grafiche e concettuali completano il quadro analitico fornendo elementi di connessione tra lettura e progetto, e quindi, di analisi e intervento sulla città esistente. L’obiettivo è di oltrepassare i limiti di strumenti di controllo della forma urbana basati sugli “stereotipi formali” delle forme del passato.
Nanotechnologies applied to building sector.
Le nanotecnologie applicate all’edilizia.
Creators: name: Rossetti, Massimo; Università Di Udine
Publisher: name: Alma Mater Studiorum, Università di Bologna
Year: 2009

description: The article presents the state of the art and the most important tendencies of one of the most promising sectors within the scenario of technological innovation in constructions: the application to materials and components of the nanotechnologies, a kind of technologies that modify at infinitesimal scale the physical, chemical and mechanical characteristics of materials in a way which is not with the traditional technologies. A sector that has seen in the last years an exponential increase of technical solutions and brevets, most of them being born in other industrial sectors and then transferred and suited for the construction industry, to improve the performances of the materials used in terms of maintenance and conservation, performances, energy saving, aesthetics.
description: L’articolo intende presentare lo stato dell’arte e le principali tendenze di uno dei settori più promettenti nel panorama dell’innovazione tecnologica nelle costruzioni: l’applicazione ai materiali e componenti per l’edilizia delle nanotecnologie, tecnologie che intervengono a scala infinitesimale per modificare le caratteristiche fisiche, chimiche e meccaniche della materia in modi altrimenti non ottenibili con le tecnologie tradizionali. Un settore che ha visto negli ultimi anni un aumento esponenziale di soluzioni tecniche e brevetti, quasi sempre nati in altri ambiti industriali e quindi trasferiti e adattati al mondo delle costruzioni, che permettono di migliorare le prestazioni dei materiali utilizzati in edilizia in termini di conservazione e manutenzione, prestazioni, risparmio energetico, aspetto.
La pédérastie dans le "Banquet" et le "Phèdre" : bonheur et finitude
Creators: name: Gravelle, Gilles
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: pratique philosophique
Éros
désir
initiation

description: La thèse entend démontrer que la droite pédérastie par sa dimension cyclique (dans le Banquet) et répétitive (dans le Phèdre) est une réponse à l'incarnation et à la finitude qui en découle, puisqu'en permettant à l’humain l’accès au Beau au moyen de la réminiscence (dans le Phèdre) et de la contemplation (dans le Banquet) ainsi qu’en offrant un modèle divin à imiter autant qu'il est possible, elle le conduit au bonheur. La droite pédérastie est ainsi une pratique eudémoniste. Platon affirme dans nombre de ses dialogues que le but de tout humain est le bonheur dont la vertu est l’élément constitutif. Lorsque l’expérience érotique sous l’égide d’Éros est correctement dirigée, l’humain peut satisfaire son désir de bonheur. Toutefois, la finitude humaine, qui s’exprime notamment par le caractère éphémère de toute possession, que ce soit celle de la connaissance ou de la vertu, prive l’humain du bonheur qu’il doit toujours reconquérir. Pour contrevenir à cette imperfection de nature, et s’approcher autant que possible du divin, le Banquet et le Phèdre proposent le recours à la droite pédérastie comme style de vie. La connaissance et la vertu ne suffisent pas au bonheur parce que celui-ci nous échappe toujours. Il faut une pratique ritualisée, la droite pédérastie, que l’humain peut répétée à chaque fois que le bonheur, la connaissance et la vertu disparaissent. C’est pourquoi la pédérastie est de nature cyclique. Il s’agit d’une pratique qu’il faut réitérer lorsque le bonheur n’est plus présent. Sans la répétition – dont la circularité imite l’éternité –, toute possession de la connaissance, de la vertu et par conséquent du bonheur est vouée à la disparition. La connaissance, la vertu et le bonheur laissent place à l’ignorance, l’intempérance et au malheur. Bien que la corporéité de l’humain soit problématique puisqu'elle porte en elle la finitude, ces deux dialogues ne proposent pas de vivre dans la pure intellection. Le corps est en effet la première étape de l’initiation érotique. Bien que la contemplation du Beau ou sa réminiscence ne soit pas immédiatement accessible, par la présence du corps désirable, l’élan érotique porte l’âme incarnée vers les belles choses, c'est-à-dire en dernier ressort vers le bonheur. La solution à la finitude humaine se découvre au cœur même de sa manifestation : le corps.
Calcium and vitamin-D deficiency marginally impairs fracture healing but aggravates posttraumatic bone loss in osteoporotic mice
Creators: name: Fischer, Verena
name: Haffner-Luntzer, Melanie
name: Prystaz, Katja
name: Vom Scheidt, Annika
name: Busse, Björn
name: Schinke, Thorsten
name: Amling, Michael
name: Ignatius, Anita
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: mineral ion homeostasis
subject: receptor-ablated mice
subject: d supplementation
subject: osteoblast differentiation
subject: global perspective
subject: elderly-patients
subject: dietary calcium
subject: rats
subject: Post-traumatic Bone Loss
subject: Intact Skeleton
subject: Callus Mineralization
subject: Reduced Bone Mass
subject: DDC 610 / Medicine & health
subject: Aged
subject: Fracture healing
subject: Hip fractures
subject: Bone density
subject: Vitamin D
subject: Calcium
subject: Homeostasis
subject: Alter
subject: Frakturheilung
subject: Knochendichte
subject: Vitamin-D-Mangel
subject: Calciummangel
subject: Homöostase

description: Calcium and vitamin-D (Ca/VitD) deficiency is a major risk factor for osteoporosis. It may also contribute to the compromised bone healing frequently observed in osteoporotic patients, since calcium is essential for fracture-callus mineralization. Additionally, clinical data suggest systemic bone loss following fracture, which may aggravate osteoporosis and thus increase the risk for fragility fractures in osteoporotic patients further. However, the role of Ca/VitD in fracture healing and posttraumatic bone turnover has to date been poorly investigated. Here, we studied bone regeneration and posttraumatic bone turnover in C57BL/6 J mice with ovariectomy-induced osteoporosis. Mice were fed a standard or a Ca/VitD-deficient diet. Notably, fracture healing was only marginally disturbed in Ca/VitD-deficient mice. However, deficient mice displayed significantly increased serum parathyroid hormone levels and osteoclast activity, as well as reduced bone mass in the intact skeleton post-fracture, suggesting considerably enhanced calcium mobilization from the intact skeleton during bone regeneration. Ca/VitD supplementation initiated post-fracture prevented posttraumatic bone loss by reducing bone resorption and furthermore improved bone repair. These results imply that adequate Ca/VitD supply post-fracture is essential to provide sufficient calcium for callus-mineralization in order to prevent posttraumatic bone loss and to reduce the risk for secondary fractures in osteoporotic patients with Ca/VitD deficiency.
Regulation of Adipocyte Lipolysis by TSH and its Role in Macrophage Inflammation
Creators: name: Durand, Jason AJ
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Adipocyte
Lipolysis
Macrophage
subclinical hypothyroidism
cardiovascular disease
TSH
thyroid-stimulating hormone
inflammation
cytokine

description: Elevated Thyroid-Stimulating Hormone (TSH) is associated with an increased risk of cardiovascular disease (CVD). We hypothesized that TSH-stimulated FA release from adipocytes contributes to macrophage inflammation. 3T3-L1 and human subcutaneous differentiated adipocytes were treated with TSH for 4 hours under various conditions and lipolysis assessed via glycerol secretion. Optimal conditions were determined and protein expression of ATGL, HSL and perilipin remained stable. TSH-stimulated 3T3-L1 or human adipocyte-conditioned medium (T-ACM) was placed on murine J774 or human THP-1 macrophages, respectively, and macrophage cytokine mRNA levels (IL-1β, IL-6, MCP-1, and TNFα) were measured by real-time RT-PCR. T-ACM did not change cytokine mRNA expression in J774 macrophages or THP-1 macrophages when compared to ACM. Absence of BSA in the medium may have hindered release of FA from differentiated adipocytes into the medium, BSA may be required to permit adequate FA accumulation in the medium to then evaluate the effect of T-ACM on macrophages. Further investigation is required to determine the effect of FA on J774 and THP-1 inflammatory response.