cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Mendelian randomization study of circulating lipids and biliary tract cancer among East Asians
Creators: name: Wang, Jun
name: Zhuge, Jinke
name: Feng, Dongxu
name: Zhang, Bo
name: Xu, Jianying
name: Zhao, Dongkang
name: Fei, Zhewei
name: Huang, Xia
name: Shi, Wenjie
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Table S1.The genetic instruments used in Mendelian analysis for high-density lipoproteincholesterol. Table S2. The geneticinstruments used in Mendelian analysis for low-density lipoprotein cholesterol.Table S3. The genetic instrumentsused in Mendelian analysis for total cholesterol. Table S4. The genetic instruments used in Mendelian analysis fortriglyceride. Table S5. Associationof biliary tract cancer with levels of circulating lipids according todifferent. Figure S1. The forestplot of leave-one-out analysis for high-density lipoprotein cholesterol. Figure S2. The forest plot ofleave-one-out analysis for low-density lipoprotein cholesterol. Figure S3. The forest plot of leave-one-outanalysis for total cholesterol. FigureS4. The forest plot of leave-one-out analysis for triglyceride. Figure S5. Results of pairwisemultivariable Mendelian randomization analysis. Figure S6. Results of multivariable Mendelian randomizationanalysis.
SGT1-HSP90 Complex Is Required for CENP-A Deposition at Centromeres
Creators: name: Niikura, Yohei
name: Kitagawa, Risa
name: Ogi, Hiroo
name: Kitagawa, Katsumi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine

description: The centromere plays an essential role in accurate chromosome segregation, and defects in its function lead to aneuploidy and thus cancer. The centromere-specific histone H3 variant CENP-A is proposed to be the epigenetic mark of the centromere, as active centromeres require CENP-A–containing nucleosomes to direct the recruitment of multiple kinetochore proteins. CENP-A K124 ubiquitylation, mediated by CUL4A-RBX1-COPS8 E3 ligase activity, is required for CENP-A deposition at the centromere. However, the mechanism that controls the E3 ligase activity of the CUL4A-RBX1-COPS8 complex remains obscure. We have discovered that the SGT1-HSP90 complex is required for recognition of CENP-A by COPS8. Thus, the SGT1-HSP90 complex contributes to the E3 ligase activity of the CUL4A complex that is necessary for CENP-A ubiquitylation and CENP-A deposition at the centromere.
Das Herbarium: Objekt und Zeugnis der Forschung.
Creators: name: Uhl, Almut
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: W. D. J. Koch
subject: Wissenschaftsgeschichte der Biologie
subject: Herbarium
subject: 570 Biowissenschaften; Biologie

description: Herbarien stellen einen außergewöhnlichen Sammlungstyp dar: Sie umfassen naturentnommene, materielle Objekte systematischer botanischer Forschung und präsentieren eine konkrete stoffliche Pflanzenbibliothek der Natur- und Wissenschaftsgeschichte. Als Pflanzenstandorte eigener Art ermöglichen sie dem Botaniker den Zugang zu den realen, morphologischen und molekularbiologischen Merkmalen von Pflanzen fernab von Raum und Zeit ihres Vorkommens. Zusammen mit den jedem Fund beigefügten Informationen bildet das Herbarium mit den ungezählten Aufsammlungen, Tauschobjekten und Züchtungen in Botanischen Gärten das materielle Substrat und dokumentierte Abbild einer langen Forschungsarbeit. Im Promotionsprojekt der Verfasserin wird eine Verknüpfung von Wissenschaftsgeschichte und aktueller sys­te­ma­tischer Forschung in der Botanik hergestellt. Der erste Teil des Projektes befasst sich mit Daten, die aus Herbarmaterial ermittelt werden können. Dies soll zu einem biographischen Überblick über Leitgedanken, Arbeitsgebiete und -weisen des Erlanger Professors Wilhelm Daniel Joseph Koch führen. Im Mittelpunkt steht das wissenschaftliche Netzwerk, das er über ganz Europa zu einer Vielzahl bekannter Botaniker seiner Zeit geknüpft hat. Ausgehend von Kochs Wirken wird die Universitäts- und Wissenschaftsgeschichte des frühen 19. Jahrhunderts beleuchtet. In einem zweiten Teil wird durch einen Vergleich von aktueller Feldbotanik und genetischen Analysen und Herbarbelegen systematische Forschung an der Pflanzengruppe Senecio nemorensis L. vorgenommen. Dazu werden Pflanzen der Senecio nemorensis-Gruppe aus dem Koch-Herbar an ihren historischen Fundorten erneut aufgesucht und morphologisch und molekular miteinander verglichen.
Elucidating the role of WRKY27 in male sterility in Arabidopsis
Creators: name: M. Shahid Mukhtar
name: Xiaoyu Liu
name: Somssich, Imre E.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: The WRKY proteins belong to a superfamily of TFs that play pivotal roles in responses to a wide range of biotic, abiotic, developmental and physiological cues. Here, we assayed the accumulation of basal WRKY27 transcripts in diverse tissue including root, shoot, leaf and flowers. We demonstrated that plants over-expressing WRKY27 transcript levels exhibit growth aberrations and fertility defects. Scanning electron microscopic data suggest that WRKY27 overexpressor plants exhibit pollen dehiscence defects. Our fluorescein diacetate hydrolysis assay showed that flowers of plants overexpressing WRKY27 display significantly decreased pollen viability. These sterility-related phenotypes were not rescued by the exogenous applications of different phytohormones. Our results indicate the involvement of WRKY27 in particular for proper plant biomass accumulation and male fertility.
Additional file 1 of Exaggerated false positives by popular differential expression methods when analyzing human population samples
Creators: name: Li, Yumei
name: Ge, Xinzhou
name: Peng, Fanglue
name: Li, Wei
name: Li, Jingyi Jessica
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Figs. S1 to S30 and Table S1.
Objektinformationsanalyse.
Creators: name: Dahlke, Christian
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: Materiale Medizingeschichte
subject: Dermatologische Moulagen
subject: Objektinformationsanalyse
subject: 610 Medizin und Gesundheit

description: Dermatologische Moulagen sind bemalte Wachsabformungen von erkrankten Hautpartien oder Körperteilen. Hautkliniken vermittelten vor gut 100 Jahren über dieses Lehrmittel Krankheitsbilder. Die Klinik und Poliklinik für Dermatologie und Venerologie an der Universitätsmedizin Rostock besitzt heute noch 32 von einst 2.000 bzw. 3.000 Moulagen. Im Sinne der Materialen Medizingeschichte dienen die genannten 32 Moulagen als Ausgangspunkt für eine Rekon­struktion der Sammlung und ihrer Geschichte. In der Dissertation des Verfassers wurde für die wissenschaftliche Untersuchung der Moulagen eine hermeneutische Methode entwickelt, die sogenannte Objektinformationsanalyse. Mit ihr werden sämtliche Objekt­informationen der Ein­zelmoulage dokumentiert und in Serie ausgewertet. Hierbei zeigten sich Phänomene, die begrifflich u. a. als Kontinui­tä­ten und Diskontinuitäten der Informationen bestimmt wurden. Die Phänomene wurden in einem weiteren Schritt his­torisch als Herstellung, Bearbeitung und Veränderung der Moulagen verstanden. Die Interpretation richtete sich zuletzt auf die mikrogeschichtlichen Zusammenhänge und wissenschaftsgeschichtlichen Diskurse. Am Beispiel des Diagnoseschildes – einem bedruckten Etikett mit einer Krankheitsbezeichnung – wird in diesem Beitrag der Weg von der Objektinformation zur Materialen Medizingeschichte aufgezeigt.
Ideologien und Kännchen.
Creators: name: Ludolph, Sophia
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: DDR-Design
subject: Mitropa
subject: rationell-Kännchen
subject: 700 Künste, Bildende und angewandte Kunst

description: Die Gestaltung der Dinge erhielt in der planwirtschaftlich organisierten DDR den Rang einer Staatsaufgabe und folgte der Prämisse, das sozialistische Lebensgefühl widerzuspiegeln und zu beeinflussen. Ökonomisches Zweckdenken in ideologischer Auslegung und kulturelle Legitimation durch traditionelle ästhetische Normensysteme charakterisierten die Produktkultur. Praxis und Theorie des Gestaltens waren dabei oftmals von Ambivalenzen geprägt, unterlagen einem Bewertungswandel und gerieten zum Politikum. Alltägliche Gegenstände wie das Kaffeekännchen der Gastronomieserie „rationell“ wurden zur umkämpften Bastion der unterschiedlichen Gestaltungsgrundsätze. Das „rationell“-Kännchen wurde 1969/70 von Margarete Jahny und Erich Müller entworfen. Innerhalb der Produktkultur der DDR nahm es eine originäre Stellung ein und ist sicherlich in jeder Sammlung, die sich der Alltags- und Kulturgeschichte Ostdeutschlands widmet, zu finden. Als Teil des am meisten verbreiteten Porzellangeschirrs in öffentlichen Einrichtungen der DDR ist es ein Repräsentant der industriellen Alltagskultur der 1970er und 1980er Jahre. Im folgenden Beitrag wird die Objektgeschichte des Kännchens, von der Genese der Form und des Dekors über die Produktion und Distribution bis hin zur Musealisierung, dargelegt. Widersprüche zwischen Anspruch und Wirklichkeit der Produktgestaltung der DDR werden offenkundig. Dabei handelt es sich nicht um eine bloße „Trivialanthropologie“ des „rationell“-Kännchens. Im Ergebnis steht vielmehr eine Schärfung des reflexiven Blicks auf die Ästhetik des Alltäglichen und deren weiterreichende Bedeutung, der sich die Autorin im Rahmen eines Dissertationsprojektes widmet.
DNA Methylation-Independent Growth Restriction and Altered Developmental Programming in a Mouse Model of Preconception Male Alcohol Exposure
Creators: name: Chang, Richard C.
name: Skiles, William M.
name: S. Chronister Sarah
name: Haiqing Wang
name: Sutton, Gabrielle I.
name: Yudhishtar S. Bedi
name: Snyder, Matthew
name: Long, Charles R.
name: Golding, Michael C.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: The preconception environment is a significant modifier of dysgenesis and the development of environmentally-induced disease. To date, Fetal Alcohol Spectrum Disorders (FASDs) have been exclusively associated with maternal exposures, yet emerging evidence suggests male-inherited alterations in the developmental program of sperm may be relevant to the growth-restriction phenotypes of this condition. Using a mouse model of voluntary consumption, we find chronic preconception male ethanol exposure associates with fetal growth restriction, decreased placental efficiency, abnormalities in cholesterol trafficking, sex-specific alterations in the genetic pathways regulating hepatic fibrosis, and disruptions in the regulation of imprinted genes. Alterations in the DNA methylation profiles of imprinted loci have been identified in clinical studies of alcoholic sperm, suggesting the legacy of paternal drinking may transmit via heritable disruptions in the regulation of imprinted genes. However, the capacity of sperm-inherited changes in DNA methylation to broadly transmit environmentally-induced phenotypes remains unconfirmed. Using bisulphite mutagenesis and second-generation deep sequencing, we find no evidence to suggest that these phenotypes or any of the associated transcriptional changes are linked to alterations in the sperm-inherited DNA methylation profile. These observations are consistent with recent studies examining the male transmission of diet-induced phenotypes and emphasize the importance of epigenetic mechanisms of paternal inheritance beyond DNA methylation. This study challenges the singular importance of maternal alcohol exposures and suggests paternal alcohol abuse is a significant, yet overlooked epidemiological factor complicit in the genesis of alcohol-induced growth defects, and may provide mechanistic insight into the failure of FASD children to thrive postnatally.
title: ADCO, Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0034
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0034, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Saint-Seine (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 165 (10 H 6, ms. 139), 354 pages, f. 0034, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Saint-Seine
description: Provenance: http://www.wikidata.org/entity/Q2820709
Lettre de Mario Maffei à [Scipione Maffei], 1744-07-10
Creators: name: Maffei, Mario
name: Maffei, Mario
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Antiquités (général)

description: Ill. sig.re Sig.re P.rone Col.mo
Sono stati ritrovati altri sepolcri etruschi con urne figurate dal sig.re Decano Giorgi, ma tutti al solito devastate, fra queste urne ve ne sono alcune con simboli nuovi, che ne ho fatte disegnare quattro delle migliori con tutta l’esattezza, e l’invio a Vs. Ill.ma, giacchè non mi è sortito poter avere due dell’istesse urne, che volevo mandarle per il suo museo. Sento che gl’antiquari di questi paesi facciano molto studio per indovinare il significato di quella, che vi è la nave, ed inclinerebbero a dire, che fosse Polifemo la figura gigantesca, ch’è in faccia alla nave, ma gli fa difficultà l’essere con ambedue gl’occhi in fronte.
A vs. Ill.ma sarà più facile il discifrarla qual’ora continui nel genio di scrivere sopra queste antichità, e può assicurarsi che il disegno è puntualissimo, e non so se saranno cosi puntuali i disegno, che anno avuto gl’altri antiquari, con quest’occasione pendo il vantaggio di rassegnare a Vs. Ill.ma il mio umilissimo ossequio, ed aver nuova della sua stimatissima persona con qualche suo stimatissimo commando mentre mi faccio sempre gloria d’essere 
Di Vs. Ill.ma 
Volterra 10 luglio 1744
Rev.do obbl. Serv.re
Mario Maffei
description: Source: [établissement de conservation] Nîmes, Bibliothèque Carré d'Art [cote] ms. 103_4, fol. 112
Additional file 3 of Exaggerated false positives by popular differential expression methods when analyzing human population samples
Creators: name: Li, Yumei
name: Ge, Xinzhou
name: Peng, Fanglue
name: Li, Wei
name: Li, Jingyi Jessica
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3. Review history.
title: ADCO, Cartulaire de Fontenay, second fragment (XIIIe siècle), Cart. 201 (15 H 9), folios 47-142, f. 055r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Fontenay, second fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), folios 47-142. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Fontenay, second fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), folios 47-142, f. 055r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Fontenay
description: Provenance: http://www.wikidata.org/entity/Q464918
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb119679755
description: Provenance: https://www.geonames.org/7874015
description: Provenance: http://www.idref.fr/027691802/id
„… der semptlichen Schifferen bruderschafft zu Nutz und Ehren“.
Creators: name: Hoppe, Lena
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: Silberschmiedekunst
subject: Lübeck
subject: Willkomm
subject: 700 Künste, Bildende und angewandte Kunst

description: Das gemeinsame Trinken und Zutrinken findet sich in so gut wie allen Kulturen und Epochen und drückt seit jeher die friedlichen Absichten der Anwesenden aus. Die hierbei verwendeten Gefäße waren zu keiner Zeit allein Gebrauchsgegenstände, sondern besaßen immer auch einen hohen symbolischen Aussagewert und wurden dementsprechend als Kommunikationsmedien eingesetzt. Hinter ihrer Gestaltung stecken bewusste und zielgerichtete Mechanismen, die Auskunft über die Wert- und Identitätsvorstellungen sozialer Gruppen geben können. Um diese zu entschlüsseln, bedarf es allerdings einer umfassenden Analyse, bei der die Zusammenhänge zwischen der formalen Gestaltung, dem ikonographischen Inhalt und dem historischen Kontext betrachtet werden. Am Beispiel des Willkomms der Lübecker Schiffergesellschaft soll in diesem Beitrag skizziert werden, mit welcher Herangehensweise der vielschichtige kulturhistorische Informationsgehalt von materiellen Objekten aufgezeigt werden kann. Es wird sich zeigen, dass der Pokal als komplexe Reaktion auf die gesellschaftspolitischen Ereignisse der Zeit zu betrachten ist und sich in ihm Sozialstrukturen der vorindustriellen Gesellschaft manifestieren.
Additional file 1 of Effectiveness of herb-partitioned moxibustion on the navel for pregnancy outcomes in patients with recurrent implantation failure undergoing in vitro fertilization and embryo transfer: a study protocol for a randomized controlled trial
Creators: name: Xia, Qingchang
name: Gao, Shuzhong
name: Song, Jingyan
name: Du, Dongqing
name: Li, Chunjing
name: Zhou, Yue
name: Zhang, Xiaobin
name: Dong, Zhibin
name: Ma, Yuning
name: Ma, Yuxia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
Additional file 1 of A multitask GNN-based interpretable model for discovery of selective JAK inhibitors
Creators: name: Wang, Yimeng
name: Gu, Yaxin
name: Lou, Chaofeng
name: Gong, Yuning
name: Wu, Zengrui
name: Li, Weihua
name: Tang, Yun
name: Liu, Guixia
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Additional file 1: Table S1. Approved JAK inhibitors and their current indications. Table S2. Some molecular graph features computed with RDKit. Table S3. Parameters’ settings of LightGBM based model for four tasks. Figure S1. Heat map of optimal hyper-parameters search for a MTATFP model. Here, the default parameters were learning rate (0.1, 0.01, 0001 and 0.0001), drop out (0.2, 0.3, 0.4, 0.5), and search for parameters at different batch size (64, 128, 256) to determine the best ones. The darker the color is, the better the R2 value of the validation set is. Figure S2. A curve graphs of Loss and R2 during training process on multitask models. Early stopping criterion for training is that the R2 on validation set is no longer improving in 20 epochs and get the best epoch 217 eventually. Figure S3. The chemical spatial distributions of the training, Davis and Anastassiadis dataset. It represented as the first three principal components of the PCA of the JAK small molecular inhibitors.
Additional file 2 of Effectiveness of herb-partitioned moxibustion on the navel for pregnancy outcomes in patients with recurrent implantation failure undergoing in vitro fertilization and embryo transfer: a study protocol for a randomized controlled trial
Creators: name: Xia, Qingchang
name: Gao, Shuzhong
name: Song, Jingyan
name: Du, Dongqing
name: Li, Chunjing
name: Zhou, Yue
name: Zhang, Xiaobin
name: Dong, Zhibin
name: Ma, Yuning
name: Ma, Yuxia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2.
The Reference System in the Model of PGE: Proposing a Generalized Description of Reference Products and their Interrelations
Creators: name: Albers, Albert
name: Rapp, Simon
name: Spadinger, Markus
name: Richter, Thilo
name: Birk, Clemens
name: Marthaler, Florian
name: Heimicke, Jonas
name: Kurtz, Victor
name: Wessels, Holger
Publisher: name: Karlsruhe
Year: 2019
Subjects: Design theory
Ontologies
Knowledge management

description: Samsung recently introduced a new smartphone display with increased breaking resistance, which will probably be relevant for future cars as well. This example shows that subsystems, in general artefacts from former development processes can be relevant for subsequent projects. Their integration has to be planned, i.a. even before the original product is in the market and across branches. The research on supporting methods requires a suitable description model for this phenomenon. Research in design reuse and PGE – product generation engineering addresses this only partially yet. Design reuse focuses on the informational aspect, PGE refers primarily to reference products. This contribution aims at closing this gap as a basis for future research. Two case studies from industry projects by the authors and an example from foresight and product planning show the role of artefacts from former development processes in running projects. It is described which artefacts are used as a reference, why they are used and when. Based on these findings the authors propose the term “reference system” to depict the whole set of artefacts, which serves as a basis for every product development project.
title: The design of Flow Injection manifolds to give the best detection limits for methods involving on-line chemical derivatisation Part 2. The spectrophotometric determination of chloride
Creators: name: Tyson, Julian
name: Fogg, A. G.
name: Wang, X.
Publisher: name: University of Massachusetts Amherst
Year: 1989
Subjects: subject: Flow injection analysis
subject: manifold design
subject: chloride determination
subject: double-line manifold
subject: noise
subject: sensitivity
subject: Analytical Chemistry
subject: FOS: Chemical sciences
subject: Chemistry

description: The optimisation of a flow injection manifold for the spectrophotometric determination of chloride is described. Factors contributing to the baseline noise due to refractive index and reagent absorption effects are removed by a combination of design features. Firstly, a double-line manifold is used; secondly, pulse-dampers and a packed bed reactor are incorporated into the flow lines and thirdly a delay coil is introduced to resolve the valve switching peaks from the determinand peaks. The appropriate conditions for obtaining the maximum sensitivity are found from an off-line experiment and the guidelines established on the basis of the well-stirred tank model for dispersion applied to the design of the operating parameters of flow rate ratio and volume injected. Good agreement between the predicted and experimentally determined values were obtained. The resulting manifold gave a linear calibration from the detection limit (4.5-8.0 ppb) to 2.00 ppm.
Additional file 1 of Characterization of the wheat VQ protein family and expression of candidate genes associated with seed dormancy and germination
Creators: name: Cheng, Xinran
name: Gao, Chang
name: Liu, Xue
name: Xu, Dongmei
name: Pan, Xu
name: Gao, Wei
name: Yan, Shengnan
name: Yao, Hui
name: Cao, Jiajia
name: Min, Xiaoyu
name: Lu, Jie
name: Chang, Cheng
name: Zhang, Haiping
name: Ma, Chuanxi
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 1: Figure S1. Sliding window plots of the VQ genes. Figure S2. Chromosomal locations of TaVQ genes. Chromosome numbers are indicated above each bar. Table S1 Detailed information about the ZmVQ, OsVQ, PtVQ and AtVQ genes. Table S2. Numbers of VQ genes and VQ genes without introns in different species. Table S3. VQ domain types in different species. Table S4. Information on 20 conserved motifs of the TaVQ protein family. Table S5. Transcriptome data for VQ genes. Table S6. Microarray data for VQ genes. Table S7. Promoter analysis of the TaVQ protein family. Table S8. Gene ontology (GO) annotations of TaVQ proteins. Table S9. Subcellular localization of TaVQs predicted by WOLF PSORT. Table S10. qRT-PCR primers for TaVQ genes. Table S11. Data of seed germination index (GI) of six wheat varieties. Table S12. Data of seed germination rate (GR) of six wheat varieties.
Additional file 1 of Metallic phase enabling MoS2 nanosheets as an efficient sonosensitizer for photothermal-enhanced sonodynamic antibacterial therapy
Creators: name: Chen, Huizhi
name: He, Xiaojun
name: Zhou, Zhan
name: Wu, Zhikang
name: Li, Hai
name: Peng, Xinsheng
name: Zhou, Yubin
name: Tan, Chaoliang
name: Shen, Jianliang
Publisher: name: figshare
Year: 2022
Subjects: Space Science
Medicine
Biological Sciences not elsewhere classified
Cancer

description: Additional file 1: Fig. S1 (a) SEM images of 2H-phase MoS2 bulk crystals and (b) its XRD pattern with simulated reference. Fig. S2 (a) TEM image of S-MoS2 nanosheets and (b) the HRTEM image of a typical S-MoS2 nanosheet. (c) AFM height image of S-MoS2 nanosheets. (d) Atomic-resolution HAADF-STEM image of a typical S-MoS2 nanosheet. (e) The filtered of the marked squire regime in (d) and (f) the corresponding crystal structure of semiconducting 2H-phase MoS2. Fig. S3 (a) UV–vis-NIR absorption spectra of M-MoS2 nanosheets dispersed in water at different concentrations and (b) its corresponding normalized absorbance intensity divided by the characteristic length of the cell (A/L) at different concentrations for λ = 1064 nm. Fig. S4 (a) Thermal images of PVP-modified M-MoS2 and PVP-modified S-MoS2 nanosheets with different concentrations (0, 10, 20, and 50 ppm) under the irradiation by a laser at 1.0 W cm−2 for 6 min. Photothermal heating curves water solutions containing (b) PVP-modified M-MoS2 and (c) PVP-modified S-MoS2 nanosheets at different concentrations (0, 5, 10, 20 and 50 ppm). (d) Photothermal heating curves water solutions containing 50 ppm PVP-modified M-MoS2 irradiated with a laser at different power density. (e) Heating of solution of 50 ppm PVP-modified M-MoS2 and S-MoS2 nanosheets for five On/Off cycles. Fig. S5 (a) The molecular structure of the reaction between RB and active oxygen species. (b,c) UV–vis spectra of RB in absence of and in presence of 50 ppm (b) M-MoS2 and (c) S-MoS2 nanosheets after US treatments with different times. Fig. S6 Relative viabilities of cells (L929) after incubation in PVP-modified M-MoS2 and S-MoS2 nanosheets with different concentrations (0, 5, 10, 20, 40, 80, 100, 120, 150 and 200 ppm) for 24 h. Fig. S7 The bacterial survival from the bacterial colonies in Fig. 5b. Fig. S8 Gram, masson trichrome, and hematoxylin–eosin (H&E) and staining of wound tissues after exposure to different treatment (PBS, M-MoS2, M-MoS2 + Laser, M-MoS2 + US, and M-MoS2 + Laser + US) for 10 days. Fig. S9 H&E staining of main organs (heart, liver, spleen, lung, and kidney) in different treatment groups.
Group compositions, solvers, discrete TADA results and video links from Social learning in otters
Creators: name: Ladds, Zosia
name: Hoppitt, William
name: Boogert, Neeltje J.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: This file contains information on otter group compositions (Table S1), number of solvers for each task in smooth-coated otters (Table S2) and Asian short-clawed otters (Table S3), discrete TADA results (Table S4) and dropbox links to Videos 1-3
Appendix A from Flexural edge waves generated by steady-state propagation of a loaded rectilinear crack in an elastically supported thin plate
Creators: name: Nobili, Andrea
name: Radi, Enrico
name: Lanzoni, Luca
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Mechanics
subject: 90506 Structural Engineering
subject: FOS: Civil engineering
subject: 10299 Applied Mathematics not elsewhere classified
subject: FOS: Mathematics

description: A conservative integral for steady-state crack propagation in an elastically supported thin plate
Supplementary data for Association between maternal fasting glucose levels throughout pregnancy and preschoolers' refractive errors.
Creators: name: Guo, Yufan
name: Zhou, Jixing
name: Lu, Jingru
name: Zhu, Linlin
name: Hao, Xuemei
name: Yan, Shuangqin
name: Tong, Juan
name: Tao, Shuman
name: Xu, Shaojun
name: Tao, Fangbiao
name: Huang, Kun
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420601
subject: Community child health

description: supplementary tables
Supplementary Material from Ancient whales did not filter feed with their teeth
Creators: name: Hocking, David P.
name: Marx, Felix G.
name: Fitzgerald, Erich M. G.
name: Evans, Alistair R.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: Supplementary Methods, Supplementary Discussion of Coronodon, Diagnosis of NMV P252376, Supplementary Tables S1-S6
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0197
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0197, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0197, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 1 of Associations of maternal exposure to fine particulate matter with preterm and early-term birth in high-risk pregnant women
Creators: name: Cao, Kaixin
name: Jin, Hongyan
name: Li, Haoxin
name: Tang, Mengmeng
name: Ge, Jianhong
name: Li, Zekang
name: Wang, Xiaoyun
name: Wei, Xuetao
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
Long-term predictions of ambient dose equivalent rates after the Fukushima Daiichi nuclear power plant accident
Creators: name: Kinase, Sakae
name: Takahashi, Tomoyuki
name: Saito, Kimiaki
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: To analyze radiation protection strategies and rehabilitation programs in Fukushima, prediction models have been developed for ambient dose equivalent rate distributions within the 80 km-radius around the Fukushima Daiichi nuclear power plant. The prediction models characterized by ecological half-lives of radioactive caesium for land-use, enable Fukushima residents to obtain distribution maps of ambient dose equivalent rates after the Fukushima Daiichi nuclear power plant accident. Model parameters such as the ecological half-lives for the short-term component and the fractional distribution of short-term component were evaluated using ambient dose equivalent rates through car/vehicle-borne surveys. It was found that the ecological half-lives among land-use differ only slightly, whereas the fractional distributions of the short-term component are clearly dependent on land-use. In addition, uncertainties concerning predictions of ambient dose equivalent rates arising from variability in model parameters were assessed using Monte Carlo simulations. Long-term changes of ambient dose equivalent rates were predicted for different land-use areas. Distribution maps of ambient dose equivalent rates for the next 30 years after the accident, created by the prediction models are expected to be useful for follow-up of the radiological situation since they provide information on the space variation of the ambient dose equivalent rates in inhabited areas.
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00152
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00152, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00152, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
VIVO: A Community-driven Research Information Management System (NISO Virtual Conference)
Creators: name: Javed, Muhammad
Publisher: name: figshare
Year: 2017
Subjects: subject: 80707 Organisation of Information and Knowledge Resources
subject: FOS: Media and communications

description: VIVO is a community-driven open source software that creates a connected, integrated record of scholarly works ready for reporting, visualization and analysis. VIVO uses Linked Data model and in the core of this application is VIVO-ISF ontology – a data model used by many institutions around the world and thus makes the data interoperable.

In this presentation, we will discuss some of the history of VIVO project and question ourselves that “is VIVO a research data recording system only”? “Can VIVO be evolved in a research information management system where VIVO not only records the data but also provides aggregate views of the scholarship and scholarly work”. Can VIVO answer questions such as “who are the experts in what subject area” without having any manual input from faculty members? Can VIVO answer questions about internal and global collaborations for a specific academic unit? Can VIVO be used to collect impact evidences of a faculty member’s research for next grant application. We will discuss the opportunities and the challenges in the light of our work “Scholars@Cornell” at Cornell University Library.
Gauss’ Law and string-localized quantum field theory
Creators: name: Mund, Jens
name: Rehren, Karl-Henning
name: Schroer, Bert
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: gauge symmetry
subject: global symmetries
subject: space-time symmetries
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: The quantum Gauss Law as an interacting field equation is a prominent feature of QED with eminent impact on its algebraic and superselection structure. It forces charged particles to be accompanied by “photon clouds” that cannot be realized in the Fock space, and prevents them from having a sharp mass [7, 19]. Because it entails the possibility of “measurement of charges at a distance”, it is well-known to be in conflict with locality of charged fields in a Hilbert space [3, 17]. We show how a new approach to QED advocated in [25, 26, 30, 31] that avoids indefinite metric and ghosts, can secure causality and achieve Gauss’ Law along with all its nontrivial consequences. We explain why this is not at variance with recent results in [8].
Additional file 3 of The use of predictive fall models for older adults receiving aged care, using routinely collected electronic health record data: a systematic review
Creators: name: Seaman, Karla
name: Ludlow, Kristiana
name: Wabe, Nasir
name: Dodds, Laura
name: Siette, Joyce
name: Nguyen, Amy
name: Jorgensen, Mikaela
name: Lord, Stephen R.
name: Close, Jacqueline C. T.
name: O’Toole, Libby
name: Lin, Caroline
name: Eymael, Annaliese
name: Westbrook, Johanna
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Information Systems not elsewhere classified
Science Policy

description: Additional file 3.
Additional file 1 of The use of predictive fall models for older adults receiving aged care, using routinely collected electronic health record data: a systematic review
Creators: name: Seaman, Karla
name: Ludlow, Kristiana
name: Wabe, Nasir
name: Dodds, Laura
name: Siette, Joyce
name: Nguyen, Amy
name: Jorgensen, Mikaela
name: Lord, Stephen R.
name: Close, Jacqueline C. T.
name: O’Toole, Libby
name: Lin, Caroline
name: Eymael, Annaliese
name: Westbrook, Johanna
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Information Systems not elsewhere classified
Science Policy

description: Additional file 1.
Additional file 2 of The use of predictive fall models for older adults receiving aged care, using routinely collected electronic health record data: a systematic review
Creators: name: Seaman, Karla
name: Ludlow, Kristiana
name: Wabe, Nasir
name: Dodds, Laura
name: Siette, Joyce
name: Nguyen, Amy
name: Jorgensen, Mikaela
name: Lord, Stephen R.
name: Close, Jacqueline C. T.
name: O’Toole, Libby
name: Lin, Caroline
name: Eymael, Annaliese
name: Westbrook, Johanna
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Information Systems not elsewhere classified
Science Policy

description: Additional file 2.
The experiences of artificial intelligence utilization in healthcare services and healthcare professionals workloads: a qualitative systematic review
Creators: name: Fernandes, Carla Sílvia
name: Martins, Maria Manuela
name: Amadigi, Felipa Rafaela
name: De Pires, Denise Elvira Pires
name: Lino, Monica Motta
name: Celuppi, Ianka Cristina
Publisher: name: OSF
Year: 2023

description: Evaluation of the experiences of artificial intelligence utilization in healthcare services and healthcare professionals workloads
The role of the lectin-like oxLDL receptor (LOX-1) in traffic-generated air pollution exposure-mediated alteration of the brain microvasculature in Apolipoprotein (Apo) E knockout mice
Creators: name: Lucero, JoAnn
name: Usa Suwannasual
name: Herbert, Lindsay M.
name: McDonald, Jacob D.
name: Lund, Amie K.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Recent studies have shown a strong correlation between air pollution-exposure and detrimental outcomes in the central nervous system, including alterations in blood brain barrier (BBB) integrity, neuroinflammation, and neurodegeneration. However, the mechanisms mediating these pathologies have not yet been fully elucidated. We have previously reported that exposure to traffic-generated air pollution results in increased circulating oxidized low-density lipoprotein (oxLDL), associated with alterations in BBB integrity, in atherosclerotic Apolipoprotein E null (ApoE−/−) mice. Thus, we investigated the role of the lectin-like oxLDL receptor (LOX)-1 in mediating these deleterious effects in ApoE−/− mice exposed to a mixture of gasoline and diesel engine exhaust (MVE: 100 PM µg/m3) for 6 h/d, 7d/week, for 30 d by inhalation. Concurrent with exposures, a subset of mice were treated with neutralizing antibodies to LOX-1 (LOX-1 Ab) i.p., or IgG (control) i.p., every other day during exposures. Resulting brain microvascular integrity, tight junction (TJ) protein expression, matrix metalloproteinase (MMP)-9/-2 activity, ROS, and markers of cellular adhesion and monocyte/macrophage sequestration were assessed. MVE-exposure resulted in decreased BBB integrity and alterations in microvascular TJ protein expression, associated with increased LOX-1 expression, MMP-9/-2 activities, and lipid peroxidation, each of which was attenuated with LOX-1 Ab treatment. Furthermore, MVE-exposure induced cerebral microvascular ROS and adhesion molecules, expression of which was not normalized through LOX-1 Ab-treatment. Such findings suggest that alterations in brain microvascular structure and integrity observed with MVE-exposure may be mediated, at least in part, via LOX-1 signaling.
VIVO: A Community-driven Research Information Management System
Creators: name: Javed, Muhammad
Publisher: name: figshare
Year: 2017
Subjects: subject: 80707 Organisation of Information and Knowledge Resources
subject: FOS: Media and communications

description: VIVO is a community-driven open source software that creates a connected, integrated record of scholarly works ready for reporting, visualization and analysis. VIVO uses Linked Data model and in the core of this application is VIVO-ISF ontology – a data model used by many institutions around the world and thus makes the data interoperable.

In this presentation, we will discuss some of the history of VIVO project and question ourselves that “is VIVO a research data recording system only”? “Can VIVO be evolved in a research information management system where VIVO not only records the data but also provides aggregate views of the scholarship and scholarly work”. Can VIVO answer questions such as “who are the experts in what subject area” without having any manual input from faculty members? Can VIVO answer questions about internal and global collaborations for a specific academic unit? Can VIVO be used to collect impact evidences of a faculty member’s research for next grant application. We will discuss the opportunities and the challenges in the light of our work “Scholars@Cornell” at Cornell University Library.
Deciding on the European Semester: the European Council, the Council and the enduring asymmetry between economic and social policy issues
Creators: name: Maricut, Adina
name: Puetter, Uwe
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: This contribution investigates the asymmetrical relationship between economic and social aspects under the European Semester by looking at the roles of the European Council and the Council between 2010 and 2016. Drawing on the theories of deliberative and new intergovernmentalism, this asymmetry is associated with an uneven evolution of the co-ordination infrastructure, notably the varying degree to which key policy issues are subject to informal policy dialogue. Not only are finance ministers better placed to conduct policy dialogue, they also control the European Semester policy priorities more effectively than their colleagues in the Employment, Social Policy, Health and Consumer Affairs Council (EPSCO). Finance ministers also are more closely linked to discussions at the highest political level, the European Council. Social affairs committees and the Commission managed to gain a greater role at the expert level and to integrate more social issues into policy recommendations. Yet, these successes are not matched by higher level political endorsement.
INVESTITSION OQIMNING YALPI ICHKI MAHSULOT (YALPI HUDUDIY MAHSULOT)GA TA`SIRINI STATISTIK BAHOLASH
Creators: name: Abdusattarova, Dilnoza
Publisher: name: Zenodo
Year: 2025

description: Yalpi ichki mahsulot (YIM) va yalpi hududiy mahsulot (YHM) - bu ikki turli iqtisodiy ko'rsatkich bo'lib, ular mamlakat yoki hududning iqtisodiy faoliyatini o'lchashda ishlatiladi. YIM barcha iqtisodiy faoliyatni o'lchaydi, shu jumladan, eksport va importni hisobga oladi, chunki u mamlakat hududidagi barcha ishlab chiqarilgan qiymatni o'z ichiga oladi. YHM esa bir hudud ichidagi faqat o'sha hududda amalga oshirilgan ishlab chiqarish faoliyatini o'lchaydi, ya'ni hududdagi ishlab chiqarilgan qiymatni hisoblaydi, import va eksportni hisobga olmaydi.