cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ПЕРЛ С БАКНИНГ «САХИЙ ЕР» РОМАНИДА ХИТОЙДА ИНҚИЛОБДАН ОЛДИНГИ ДАВРДА СОДИР БЎЛГАН ГЛОБАЛ ЎЗГАРИШЛАРНИНГ БАДИИЙ  ИНЪИКОСИ
Creators: name: Маманабиева, Шахризода
Publisher: name: Zenodo
Year: 2024

description: Мазкур тезисда Хитой  халқининг улуғ анъаналари, хитойлик оилаларнинг эътиқодлари, стратегияси  ва одатлари, Хитойда инқилобдан олдинги даврда содир бўлган ўзгаришларнинг жиддийлиги ҳақида Америка ёзувчиси талқинида  жўшиб гапирилади. Бундай  ўзига  хослиги   билан тезисда биринчи жаҳон  урушидан кейинги   Хитой   давлати   ҳаётида,  Шарқ  ва  Ғарб  халқлари ўртасида дўстона муносабатларнинг сақланиб қолинишига салмоқли таъсир кўрсатганлигини ўрганишга  ҳаракат  қилинган.
Alternative Estimation Prodecures For Multiplicative Models: Implications for Projecting Recreational Use
Creators: name: Green, Richard
name: Johnston, Warren
name: Green, Richard
name: Johnston, Warren
Publisher: name: Unknown
Year: 1975
Subjects: Resource /Energy Economics and Policy

description: This paper deals with the difficulties in using results from multiplicative models of recreational use(demand) for projecting recreational use of for estimating consumer surplus values and offers alternatives--theoretically optimal MSE-estimators--to traditional OLS estimators. Empirical comparisons of OLS and alternative estimators are given.
Determination of the Higgs-boson couplings and H-A mixing in the generalized SM-like Two Higgs Doublet Model
Creators: name: Niezurawski, P.
name: Zarnecki, A. F.
name: Krawczyk, M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The feasibility of measuring the Higgs-boson properties at the Photon Collider at TESLA has been studied in detail for masses between 200 and 350 GeV, using realistic luminosity spectra and detector simulation. We consider the Two Higgs Doublet Model (II) with SM-like Yukawa couplings for h, parametrized by only one parameter (tan(beta)). The combined measurement of the invariant-mass distributions in the ZZ and W+W- decay-channels is sensitive to both the two-photon width Gamma_{gamma gamma} and phase Phi_{gamma gamma}. From the analysis including systematic uncertainties we found out that after one year of Photon Collider running with nominal luminosity the expected precision in the measurement of tan(beta) is of the order of 10%, for both light (h) and heavy (H) scalar Higgs bosons. The H-A mixing angle Phi_{HA}, characterizing a weak CP violation in the model with two Higgs doublets, can be determined to about 100 mrad, for low tan(beta).
description: 17 pages, 9 figures; published version
The variety of dual mock-Lie algebras
Creators: name: Camacho, Luisa M.
name: Kaygorodov, Ivan
name: Lopatkin, Victor
name: Salim, Mohamed A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics

description: We classify all complex $7$- and $8$-dimensional dual mock-Lie algebras by algebraic and geometric way. Also we find all non-trivial complex $9$-dimensional dual mock-Lie algebras.
description: arXiv admin note: substantial text overlap with arXiv:1905.05361 and text overlap with arXiv:1907.00685
Suitable Design for Electromagnetic Pulse Processes
Creators: name: Marschner, O.
name: Pabst, C.
name: Schäfer, R.
name: Pasquale, P.
Publisher: name: TU Dortmund
Year: 2021
Subjects: subject: electromagnetic pulse processes
subject: crimping
subject: welding
subject: electrical mobility
subject: 620
subject: 670

description: Basic conventional production processes, such as arc welding or forming, are more or less thoroughly investigated, reliable process guidelines have been developed and trained engineers are available. This allows them to be put into use usually fast, thus facilitating a wide application. The usage of electromagnetic pulse processes, on the contrary, still lacks a broad propagation. Despite having a history reaching back several decades, these processes are mostly limited to niche applications. Admittedly, theoretical considerations have been made and various experiments have been carried out. However, when a given joining or forming task needs to be realized with electro-magnetic force, a huge invest is necessary even before the first part is made. This involves the design of the machine, especially of the tool coil, as well as the design of the workpieces to be processed. In industrial environmentsthis challenge is tackled step by step: After the theoretical product concept in close collaboration with the customer, numerical and experimental trials are carried out. In many cases, iterations are necessary and both geometry and process are optimized. The experimental trials can be conducted with universal sheet welding tool coils or tube compression tool coils with custom field shapers. This procedure allows keeping the prototyping costs low, but at the same time provides valid information on the feasibility in general, the requirements to the workpieces, the design of the tool coil and the properties of the pulse generator. Subsequently, the tool coil is designed and manufactured according to the prior findings. The pulse generator as modular component is assembled and adapted to the customer’s requirements. The iterative product and process design is the most important phase of the whole procedure, which is in accordance with good project management. It significantly lowers the risk of an expensive project cancellation during the late steps.
The World Sugar Economy
Creators: name: Abou-Bakr, Ahmed
name: Harrington, A.H.
name: Abou-Bakr, Ahmed
name: Harrington, A.H.
Publisher: name: Unknown
Year: 1975
Subjects: Demand and Price Analysis

description: This paper is designed to describe and analyze the recent operation of the world sugar economy under what we call protection or control policy. The analysis is also extended to study the effect Of the removal of protectionist policy on world sugar supply, demand and price.
Coherent Quantum Channel Discrimination
Creators: name: Wilde, Mark M.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: This paper introduces coherent quantum channel discrimination as a coherent version of conventional quantum channel discrimination. Coherent channel discrimination is phrased here as a quantum interactive proof system between a verifier and a prover, wherein the goal of the prover is to distinguish two channels called in superposition in order to distill a Bell state at the end. The key measure considered here is the success probability of distilling a Bell state, and I prove that this success probability does not increase under the action of a quantum superchannel, thus establishing this measure as a fundamental measure of channel distinguishability. Also, I establish some bounds on this success probability in terms of the success probability of conventional channel discrimination. Finally, I provide an explicit semi-definite program that can compute the success probability.
description: 12 pages, 5 figures, submission to ISIT 2020
Clinical development of valbenazine for tics associated with Tourette syndrome
Creators: name: Farber, Robert H.
name: Angelov, Angel
name: Kim, Kristine
name: Carmack, Tara
name: Thai-Cuarto, Dao
name: Roberts, Eiry
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Introduction: Significant need exists for effective, well-tolerated pharmacologic treatments for Tourette syndrome (TS). Medications that inhibit vesicular monoamine transporters (i.e. VMAT2 inhibitors) downregulate presynaptic packaging and release of dopamine into the neuronal synapse and are effective in treating hyperkinetic movement disorders such as Huntington’s chorea and tardive dyskinesia (TD); thus, they may be useful in treating TS. Areas covered: This review describes the clinical program evaluating the safety and efficacy of valbenazine in the treatment of involuntary tics associated with TS in adult and pediatric subjects. While there was a trend in the 6 completed trials toward greater improvement in valbenazine-treated versus placebo subjects on the primary efficacy endpoint (Yale Global Tic Severity Scale Total Tic Score), this difference did not reach statistical significance. Valbenazine was generally well-tolerated in the studies, and treatment-emergent adverse events were consistent with valbenazine studies in TD. Expert opinion: Due to the failure to meet the primary endpoint in these trials, further investigation of valbenazine for TS is unlikely. Given the need for safe and effective TS therapies and the key role of VMAT2 in modulating dopaminergic activity, it is reasonable for future studies to investigate other VMAT2 inhibitors as potential treatments for TS.
Leptostylus pulcherrimus Bates 1880
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Leptostylus
Leptostylus pulcherrimus

description: 61. Leptostylus pulcherrimus Bates, 1880
Type locality — Mexico, Veracruz: Córdoba. (BMNH). Distribution — Mexico (Veracruz) to Nicaragua.
 Leptostylus pulcherrimus Bates, 1880a: 148; Lameere, 1883: 69 (cat.); Chemsak et al., 1992: 140 (cat.); Noguera & Chemsak, 1996: 406 (cat.).
description: Published as part of Monné, Miguel A., 2005, Catalogue of the Cerambycidae (Coleoptera) of the Neotropical Region. Part II. Subfamily Lamiinae, pp. 1-760 in Zootaxa 1023 (1) on pages 1-760, DOI: 10.11646/zootaxa.946.1.1, http://zenodo.org/record/5049553
Codes from symmetric polynomials
Creators: name: Datta, Mrinmoy
name: Johnsen, Trygve
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Theory (cs.IT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 05E45, 94B05, 05B35, 13F55

description: We define and study a class of Reed-Muller type error-correcting codes obtained from elementary symmetric functions in finitely many variables. We determine the code parameters and higher weight spectra in the simplest cases.
Asymmetry index of entrance use from Multiple nest entrances alter foraging and information transfer in ants
Creators: name: Lehue, Marine
name: Collignon, Bertrand
name: Detrain, Claire
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: The table presents the asymmetry index of entrance use measured after 5 and 120 minutes.
Accelerating Cosmologies from S-Branes
Creators: name: Ohta, Nobuyoshi
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We point out that the recently proposed model of a flat 4-dimensional universe with accelerated expansion in string/M-theory is a special case of time-dependent solutions that the author found under the name of ``S-branes.'' We also show that similar accelerating models can be obtained from S-branes if the internal space is chosen to be hyperbolic or flat spaces.
description: 8 pages, 4 figures, comments added, a typo corrected, final version to appear in Phys. Rev. Lett
Sarcosine as an add-on treatment to antipsychotic medication for people with schizophrenia: a systematic review and meta-analysis of randomized controlled trials
Creators: name: Marchi, Mattia
name: Galli, Giacomo
name: Magarini, Federica Maria
name: Mattei, Giorgio
name: Galeazzi, Gian Maria
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background: N-methyl-glycine (sarcosine) may improve symptoms of schizophrenia via NMDA-receptor modulation. We undertook a systematic review and meta-analysis to determine the short- and long-term effectiveness of sarcosine for schizophrenia. Research design and methods: The databases Medline, Scopus, EMBASE, Cochrane Library, and PsycINFO were searched. We included six independent randomized controlled trials of sarcosine as add-on treatment to current antipsychotic medication, involving 234 adult participants with schizophrenia, and reporting data on symptom severity. Standardized mean differences (SMDs) were used to assess continuous outcomes. Results: In all of the trials, sarcosine was administered orally at 2 g/day. Treatment with sarcosine did not show a significant effect size at any of the pre-established time points (2, 4, 6, or >6 weeks), due to marked quantitative heterogeneity. However, sarcosine was associated with significant reductions of symptom severity in the subgroups of people with chronic schizophrenia and no treatment resistance (namely, without added-on clozapine) in relation to the SMD after 6 weeks treatment at −0.36 and −0.31, respectively. Conclusions: People with chronic and non-refractory schizophrenia may benefit from the use of sarcosine as an add-on treatment to antipsychotic medication. Due to the good tolerability of this compound, future trials with larger sample sizes appear worthwhile.
Transportation in Rural America--Problems and Research Needs
Creators: name: Reinsel, Edward I.
name: Reinsel, Edward I.
Publisher: name: Unknown
Year: 1975
Subjects: Public Economics

description: Rural transportatipn problems seem less acute than two years ago. However, problems remain and extensive multi-disciplinary research on major modes is suggested. Mobility problems of people and relationships between rural development and transportation require study. Forecasting of supply and demand for services is needed. ERS transportation research is outlined.
INCOMMENSURABLES, TRADEOFFS AND THE MULTIPLE PRODUCT MODELS: WHY THE CONFUSION
Creators: name: Lynne, Gary D.
name: Lynne, Gary D.
Publisher: name: Unknown
Year: 1975
Subjects: Health Economics and Policy

description: The outline of this paper is as follows. First, a conceptual model is presented that is useful for dealing with the multiple objective problem. The model is very familiar to, I hope, all production economists and those economists who find the study of welfare economics a useful endeavor. Second, it will be shown where several attempts to deal with the multiple objective problem have gone awry. Third, a simplified example will be presented which illustrates an attempt at" applying the conceptual lesson that must be learned by all those analysts, concerned with multiple objective planning.
A non-equilibrium quantum many-body Rydberg atom engine
Creators: name: Carollo, Federico
name: Gambetta, Filippo M.
name: Brandner, Kay
name: Garrahan, Juan P.
name: Lesanovsky, Igor
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The standard approach to quantum engines is based on equilibrium systems and on thermodynamic transformations between Gibbs states. However, non-equilibrium quantum systems offer enhanced experimental flexibility in the control of their parameters and, if used as engines, a more direct interpretation of the type of work they deliver. Here we introduce an out-of-equilibrium quantum engine inspired by recent experiments with cold atoms. Our system is connected to a single environment and produces mechanical work from many-body interparticle interactions arising between atoms in highly excited Rydberg states. As such, it is not a heat engine but an isothermal one. We perform many-body simulations to show that this system can produce work. The setup we introduce and investigate represents a promising platform for devising new types of microscopic machines and for exploring quantum effects in thermodynamic processes.
description: 10 pages, 5 figures
ADAPTATIONS OF REACTIVE PROGRAMMING IN SPATIAL AND TEMPORAL SIMULATION ANALYSIS
Creators: name: O'Rourke, A. Desmond
name: O'Rourke, A. Desmond
Publisher: name: Unknown
Year: 1975
Subjects: Research and Development/Tech Change/Emerging Technologies

description: This paper reviews some of the conceptual and practical problems which have arisen in the application of reactive programming to spatial and temporal studies of Northwest agriculture. It suggests that while reactive programming has passed the test as an effective tool for applied research, its potential and its limitations are not yet fully understood.
Leptostylus quintalbus Bates 1885
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Leptostylus
Leptostylus quintalbus

description: 63. Leptostylus quintalbus Bates, 1885
Type locality — Panama, Chiriquí: Bugaba. (BMNH). Distribution — Panama.
 Leptostylus quintalbus Bates, 1885: 389, pl. 24, fig. 2; Chemsak & Linsley, 1970: 412 (lect.); Chemsak et al., 1992: 140 (cat.).
description: Published as part of Monné, Miguel A., 2005, Catalogue of the Cerambycidae (Coleoptera) of the Neotropical Region. Part II. Subfamily Lamiinae, pp. 1-760 in Zootaxa 1023 (1) on pages 1-760, DOI: 10.11646/zootaxa.946.1.1, http://zenodo.org/record/5049553
Analyzing Control Flow Integrity with LLVM-CFI
Creators: name: Muntean, Paul
name: Neumayer, Matthias
name: Lin, Zhiqiang
name: Tan, Gang
name: Grossklags, Jens
name: Eckert, Claudia
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Control-flow hijacking attacks are used to perform malicious com-putations. Current solutions for assessing the attack surface afteracontrol flow integrity(CFI) policy was applied can measure onlyindirect transfer averages in the best case without providing anyinsights w.r.t. the absolute calltarget reduction per callsite, and gad-get availability. Further, tool comparison is underdeveloped or notpossible at all. CFI has proven to be one of the most promising pro-tections against control flow hijacking attacks, thus many effortshave been made to improve CFI in various ways. However, there isa lack of systematic assessment of existing CFI protections. In this paper, we presentLLVM-CFI, a static source code analy-sis framework for analyzing state-of-the-art static CFI protectionsbased on the Clang/LLVM compiler framework.LLVM-CFIworksby precisely modeling a CFI policy and then evaluating it within aunified approach.LLVM-CFIhelps determine the level of securityoffered by different CFI protections, after the CFI protections weredeployed, thus providing an important step towards exploit cre-ation/prevention and stronger defenses. We have usedLLVM-CFIto assess eight state-of-the-art static CFI defenses on real-worldprograms such as Google Chrome and Apache Httpd.LLVM-CFIprovides a precise analysis of the residual attack surfaces, andaccordingly ranks CFI policies against each other.LLVM-CFIalsosuccessfully paves the way towards construction of COOP-like codereuse attacks and elimination of the remaining attack surface bydisclosing protected calltargets under eight restrictive CFI policies.
description: Accepted for publication at ACSAC'19 conference. arXiv admin note: substantial text overlap with arXiv:1812.08496
Comparison of the methods for discrete approximation of the fractional-order operator
Creators: name: Dorcak, L.
name: Petras, I.
name: Terpak, J.
name: Zborovjan, M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 26A33, 93C55 (Primary) 65D25, 93C05 (Secondary)

description: In this paper we will present some alternative types of discretization methods (discrete approximation) for the fractional-order (FO) differentiator and their application to the FO dynamical system described by the FO differential equation (FDE). With analytical solution and numerical solution by power series expansion (PSE) method are compared two effective methods - the Muir expansion of the Tustin operator and continued fraction expansion method (CFE) with the Tustin operator and the Al-Alaoui operator. Except detailed mathematical description presented are also simulation results. From the Bode plots of the FO differentiator and FDE and from the solution in the time domain we can see, that the CFE is a more effective method according to the PSE method, but there are some restrictions for the choice of the time step. The Muir expansion is almost unusable.
description: PDF Version 1.3, 6 pages, 4 figures
First eROSITA-TESS results for M dwarfs: Mass dependence of the X-ray activity rotation relation and an assessment of sensitivity limits
Creators: name: Magaudda, E.
name: Stelzer, B.
name: Raetz, St.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present a study of the activity-rotation relation for M dwarf stars, using new X-ray data from the ROentgen Survey with an Imaging Telescope Array (eROSITA) on board the Russian Spektrum-Roentgen-Gamma mission (SRG), combined with photometric rotation periods from the Transiting Exoplanet Survey Satellite (TESS). The stars used in this work are selected from the superblink proper motion catalog of nearby M dwarfs. We study the 135 stars with both a detection in the first eROSITA survey (eRASS1) and a rotation period measurement from TESS jointly with the sample of 197 superblink M dwarfs re-adapted from our previous work. We fit the activity-rotation relation for stars with rotation periods shorter than ~10 d (saturated regime) using three mass bins. The surprising positive slope for stars in our lowest mass bin ($M_{\star} \leq 0.4 {\rm M_\odot}$) is due to a paucity of stars with intermediate rotation periods (~ 1-10 d), probably caused by fast period evolution. The much higher fraction of eRASS1 detections compared to stars that have also rotation periods from TESS shows that eROSITA is also sensitive for slower rotating M dwarfs that are in the unsaturated regime with periods inaccessible to TESS.
Development of culture-free methods for selecting host-specific bacteriophages and the characterisation of unusual bacteriophages
Creators: name: Imam, Mohammed A. A.
Publisher: name: University of Leicester
Year: 2020
Subjects: Uncategorized

description: Bacteriophages show great potential in many applications. Their abundance exceeds the bacterial population by ten-fold. Studying phages and their characteristics requires culturing of the bacterial host, allowing the phage to propagate by lysing cells forming plaques on a bacterial lawn. However, the number of isolated host-specific phages does not reflect the wide variety of phages in the environment.This study aimed to design a culture-independent method of selecting host-specific bacteriophages from complex mixtures of bacteriophages. Firstly, lipopolysaccharides (LPS) were used to isolate host-specific phages. Pseudomonas LPS was immobilised onto glass beads to work as an affinity sorbent that selects for only Pseudomonas aeruginosa phages. It was observed that phages non-specifically bound to the beads and remained bound even after multiple washing steps. Therefore, another method was devised involving the use of outer membrane vesicles (OMVs) to select for the DNA of host-specific phages. Analysis of the OMV-based method revealed successful selection of a P. aeruginosa phage from a mixture containing different known phages, as assessed by PCR. Further optimisation is required to apply this method to analyse environmental samples containing a complex mixture of unknown phages.During this study, novel bacteriophages infecting P. aeruginosa and E. coli strains were isolated from a horse manure sample by the traditional method of phage isolation (plaque assay). Genomic and biological analysis of these isolated phages revealed the presence of unusual features. One of the isolated phages was, phage MIJ3. This is a jumbo phage which has genome size of 288,170bp; it is capable of infecting most of the P. aeruginosa Liverpool Epidemic Strains along with other multi-drug resistant strains. Bioinformatic analysis of the phage genome revealed that the phage encodes several “host-like” proteins, some of which have not been reported in phages before.Another isolated phage from the horse sample was phage MiEL, which has a genome size of 176,867 bp. Phage MiEL infects a variety of E. coli clinical strains isolated from urinary tract infection patients. It is also able to enter a pseudolysogenic state during poor bacterial growth conditions. Thus, novel phages infecting clinical strains can be isolated from a variety of sources.
Xanthones as P-glycoprotein modulators and their impact on drug bioavailability
Creators: name: Silva, Vera
name: Gil-Martins, Eva
name: Silva, Bárbara
name: Rocha-Pereira, Carolina
name: Sousa, Maria Emília
name: Remião, Fernando
name: Silva, Renata
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Plant Biology
subject: FOS: Biological sciences

description: Introduction: P-glycoprotein (P-gp) is an important efflux pump responsible for the extruding of many endogenous and exogenous substances out of the cells. P-gp can be modulated by different molecules – including xanthone derivatives – to surpass the multidrug resistance (MDR) phenomenon through P-gp inhibition, or to serve as an antidotal strategy in intoxication scenarios through P-gp induction/activation. Areas covered: This review provides a perspective on P-gp modulators, with particular focus on xanthonic derivatives, highlighting their ability to modulate P-gp expression and/or activity, and the potential impact of these effects on the pharmacokinetics, pharmacodynamics and toxicity of P-gp substrates. Expert opinion: Xanthones, of natural or synthetic origin, are able to modulate P-gp, interfering with its protein synthesis or with its mechanism of action, by decreasing or increasing its efflux capacity. These modulatory effects make the xanthonic scaffold a promising source of new derivatives with therapeutic potential. However, the mechanisms beyond the xanthones-mediated P-gp modulation and the chemical characteristics that make them more potent P-gp inhibitors or inducers/activators are still understudied. Furthermore, a new window of opportunity exists in the neuropathologies field, where xanthonic derivatives with potential to modulate P-gp should be further explored to optimize the prevention/treatment of brain pathologies.
EXPLANATION AND USE OF AN AGRICULTURAL POLICY SIMULATOR(POLYSIM)
Creators: name: Ray, Daryll E.
name: Mariak, Theo F.
name: Ray, Daryll E.
name: Mariak, Theo F.
Publisher: name: Unknown
Year: 1975
Subjects: Agricultural and Food Policy

description: Decision makers at all levels need information on available options and the likely impacts of pursuing those options. National agricultural policy makers are, of course, among those that have a continuing need for up-to-date and accurate information for use in decision making. As an aid to providing expanded and more complete information to agricultural policy makers, an agricultural policy simulator has been developed and implemented for analysis of alternative agricultural policy proposals and economic conditions.
We are what we eat: An economic tool for tracing the origins of nutrients with entry points for action
Creators: name: Rutten, Martine
name: Tabeau, Andrzej
name: Godeschalk, Frans
name: Rutten, Martine
name: Tabeau, Andrzej
name: Godeschalk, Frans
Publisher: name: Unknown
Year: 2014
Subjects: subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: Food security
subject: diets
subject: nutrition
subject: health
subject: food supply chain
subject: economy-wide scenario analysis

description: We develop a methodology for incorporating nutrition impacts in economy-wide analyses, providing entry points for where, when and how to act. It accounts for three channels of consumption, directly via primary commodities and indirectly via processed foods and food-related services, and produces indicators showing content by nutrient (currently calories, proteins, fats and carbohydrates), channel, source region and sector. The paper applies the framework in a CGE model (MAGNET) and uses FAO data to project nutritional outcomes resulting from the global food system over time. The analysis confirms that developing regions catch up with developed regions, with the USA at the high-end of nutrient consumption, whilst Southern Africa lags behind. In the USA the processed food channel dominates, whereas in Southern Africa the direct channel dominates. In the USA, and similar regions, fat taxes (thin subsidies) on unhealthy (healthy) processed foods, technologies reducing bad ingredients (e.g. trans fats, salt), improved food labelling, information and marketing campaigns, and/or targeted cash transfers may be worthwhile to investigate. In Southern Africa, and regions alike, technological advances increasing nutrient availability via primary agriculture and/or cash transfers enabling access may be more pertinent. The relative fixedness of sectoral origins shows that consumption habits change slowly and are visible only in the long term. For certain regions, including Southern Africa and USA, nutrient import dependency increases with substantial variations in regional sourcing. This implies that concerted action across the globe is crucial to reach diet, nutrition and health goals, and should include upcoming Asian economies, Africa (excl. Southern Africa) and the Middle East. Heterogeneity of results necessitates future ex-ante quantitative policy analyses on a more detailed and context-specific basis.
Leptostylus sleeperi Hovore 1988
Creators: name: Monné, Miguel A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Leptostylus
Leptostylus sleeperi

description: 68. Leptostylus sleeperi Hovore, 1988
Type locality — Mexico, Baja California: 26 mi S Santa Rosalía. (CASC). Distribution — Mexico (Baja California).
 Leptostylus sleeperi Hovore, 1988: 22, fig. 4c; Chemsak et al., 1992: 141 (cat.); Noguera & Chemsak, 1996: 406 (cat.).
description: Published as part of Monné, Miguel A., 2005, Catalogue of the Cerambycidae (Coleoptera) of the Neotropical Region. Part II. Subfamily Lamiinae, pp. 1-760 in Zootaxa 1023 (1) on pages 1-760, DOI: 10.11646/zootaxa.946.1.1, http://zenodo.org/record/5049553
A Mirage or an Oasis? Water Vapor in the Atmosphere of the Warm Neptune TOI-674 b
Creators: name: Brande, Jonathan
name: Crossfield, Ian J. M.
name: Kreidberg, Laura
name: Oklopčić, Antonija
name: Polanski, Alex S.
name: Barman, Travis
name: Benneke, Björn
name: Christiansen, Jessie L.
name: Dragomir, Diana
name: Foreman-Mackey, Daniel
name: Fortney, Jonathan J.
name: Greene, Thomas P.
name: Howard, Andrew W.
name: Knutson, Heather A.
name: Lothringer, Joshua D.
name: Mikal-Evans, Thomas
name: Morley, Caroline V.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We report observations of the recently discovered warm Neptune TOI-674 b (5.25 \rearth{}, 23.6 \mearth{}) with the Hubble Space Telescope's Wide Field Camera 3 instrument. TOI-674 b is in the Neptune desert, an observed paucity of Neptune-size exoplanets at short orbital periods. Planets in the desert are thought to have complex evolutionary histories due to photoevaporative mass loss or orbital migration, making identifying the constituents of their atmospheres critical to understanding their origins. We obtained near-infrared transmission spectroscopy of the planet's atmosphere with the G141 grism. After extracting, detrending, and fitting the spectral lightcurves to measure the planet's transmission spectrum, we used the petitRADTRANS atmospheric spectral synthesis code to perform retrievals on the planet's atmosphere to identify which absorbers are present. These results show moderate evidence for increased absorption at 1.4 $μ$m due to water vapor at 2.9$σ$ (Bayes factor = 15.8), as well as weak evidence for the presence of clouds at 2.2$σ$ (Bayes factor = 4.0). TOI-674 b is a strong candidate for further study to refine the water abundance, which is poorly constrained by our data. We also incorporated new TESS short-cadence optical photometry, as well as Spitzer/IRAC data, and re-fit the transit parameters for the planet. We find the planet to have the following transit parameters: $R_p/R_* = 0.1135\pm0.0006$, $T_0 = 2458544.523792\pm0.000452$ BJD, and $P = 1.977198\pm0.00007$ d. These measurements refine the planet radius estimate and improve the orbital ephemerides for future transit spectroscopy observations of this highly intriguing warm Neptune.
description: Accepted to the Astronomical Journal. 20 pages, 17 figures
High Resolution Images of Orbital Motion in the Trapezium Cluster: First Scientific Results from the MMT Deformable Secondary Mirror Adaptive Optics System
Creators: name: Close, Laird M.
name: Wildi, Francois
name: Lloyd-Hart, Michael
name: Brusa, Guido
name: Fisher, Don
name: Miller, Doug
name: Riccardi, Armando
name: Salinari, Piero
name: McCarthy, Donald W.
name: Angel, Roger
name: Allen, Rich
name: Martin, H. M.
name: Sosa, Richard G.
name: Montoya, Manny
name: Rademacher, Matt
name: Rascon, Mario
name: Curley, Dylan
name: Siegler, Nick
name: Duschl, Wolfgang J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the first scientific images obtained with a deformable secondary mirror adaptive optics system. We utilized the 6.5m MMT AO system to produce high-resolution (FWHM=0.07'') near infrared (1.6 um) images of the young (~1 Myr) Orion Trapezium theta 1 Ori cluster members. A combination of high spatial resolution and high signal to noise allowed the positions of these stars to be measured to within ~0.003'' accuracies. Including previous speckle data (Weigelt et al. 1999), we analyze a six year baseline of high-resolution observations of this cluster. Over this baseline we are sensitive to relative proper motions of only ~0.002''/yr (4.2 km/s at 450 pc). At such sensitivities we detect orbital motion in the very tight theta 1 Ori B2B3 (52 AU separation) and theta 1 Ori A1A2 (94 AU separation) systems. Such motions are consistent with those independently observed by Schertl et al. (2003) with speckle interferometry, giving us confidence that these very small (~0.002''/yr) orbital motions are real. All five members of the theta 1 Ori B system appear likely gravitationally bound. The very lowest mass member of the theta 1 Ori B system (B4) has K' ~11.66 and an estimated mass of ~0.2 Msun. There was very little motion (4+/-15 km/s) detected of B4 w.r.t B1 or B2, hence B4 is possibly part of the theta 1 Ori B group. We suspect that if this very low mass member is physically associated it most likely is in an unstable (non-hierarchical) orbital position and will soon be ejected from the group. The theta 1 Ori B system appears to be a good example of a star formation ``mini-cluster'' which may eject the lowest mass members of the cluster in the near future. This ``ejection'' process could play a major role in the formation of low mass stars and brown dwarfs.
description: To appear in the December 10, 2003 issue of the Astrophysical Journal 21 pages, 14 figures (some in color, but print OK in B&W)
Impact of work-life balance on Employee turnover and turnover intentions.pdf
Creators: name: Rabbir Rashedin Tirno
Publisher: name: figshare
Year: 2021
Subjects: subject: 150305 Human Resources Management
subject: FOS: Economics and business

description: Work-life balance (WLB) is one of the burning issues in the business arenas to ensure the sustainable steady performance of the organizations. Work-life balance influences the turnover and turnover intentions of the employees which are the indicators of employees’ job satisfaction. In this rapid growing world, majority of the business sectors are now being occupied by giant Multinational Corporations, hence it is very challenging for the organizations to compete in this competitive world without satisfied motivated employees. The aim of this study is to find the impact of work-life balance on employees’ turnover and turnover intentions of multinational corporations working in Bangladesh. The research is basically based on primary data collected from different multinational corporations from different industries such as telecom, tobacco, fashion, consumer goods. To test the hypotheses different statistical tools such as One sample t test, ANOVA test, Correlation were used based on survey data. Linear regression analysis executed to establish a model to find out the impact of various dependent variables over independent variable. From the analysis of the survey it was found that poor work life balance leads to higher employees turnover and turnover intentions and proper work-life balance of employees has a positive effect over the performance of the organizations.
USO DE COMPUTAÇÃO PREDITIVA POR ANCORAGEM MOLECULAR DE COMPOSTOS DO ÓLEO ESSENCIAL DE COPAIFERA LANGSDORFFII DESF COMO INIBIDORES DO SARS-COV-2
Creators: name: COSTA, R.B.G.M.
name: MARTINS, R.M.G.
name: STAMFORD, T.C.M.
name: MACIEL, M.A.M
name: XAVIER-JUNIOR, F.H.
Publisher: name: figshare
Year: 2021
Subjects: Biotechnology

description: O atual cenário causado pelo novo coronavirus (SARS-CoV-2019) trouxe a imperativa necessidade de desenvolvimento de pesquisas que visem amortizar a taxa de transmissão, a busca da cura e de tratamentos que promovam a redução de mortes de indivíduos acometidos por Covid-19. Neste contexto, a pesquisa de novas substâncias de combate ao vírus que explora compostos naturais oriundos da flora brasileira tem um papel muito importante. O presente trabalho estudou a interação dos principais compostos do óleo essencial de Copaíba (Copaifera langsdorffii Desf) contra os 15 principais alvos conhecidos que favorecem a entrada do novo Coronavirus (SARS-CoV-2) no corpo humano: SARS-CoV-2 Mpro (protease principal), endoribonuclease NSP-15, RNA polimerase RNA?dependente, ECA-2 e domínio Spike-S, através de uma análise computacional in-silico. A caracterização do óleo de copaíba foi realizada por cromatografia gasosa acoplada a espectrofotometria de massas (CG-MS). AutoDockTools 4.2, AutoDock Vina, APBS e PyMol foram usados para a pesquisa de acoplamento e interação molecular. As moléculas estudadas foram previamente tratadas, desidratadas, adicionado hidrogênios em cadeias polares e plotado em um grid proporcional suficiente para encobrir as macromoléculas e os ligantes. O óleo essencial de copaíba apresentou 10 principais moléculas analisadas por cromatografia, com destaque para o β-bisaboleno (23,6%), β-cariofileno (21,7%) e α-bergamoteno (20,5%), corroborando com resultados encontrados por outros autores. O β-selineno (6.1%) apresentou um resultado de energia de ligação significativo de -7.2 , ligando-se a nove aminoácidos através de ligações hidrofóbicas na protease principal do vírus (SARS-CoV-2 Mpro). Ademais, as superfícies eletrostáticas obtidas através do uso do APBS (Advanced Poisson-Boltzmann Solver) demonstrou que a molécula liga-se no isocontorno da superfície de potencial eletrostático, demonstrando uma afinidade com regiões apolares, ligando-se por interações hidrofóbicas com os resíduos: Phe 3, Arg 4, Lis 5, Phe 291, Glu 288, Trp 207 e Leu 282, todos encontrados na cadeia A da protease principal do vírus. Os demais compostos estudados presentes no óleo essencial também apresentaram excelentes resultados de energia de ligação contra os principais alvos de inibição considerados neste estudo, indicando um importante caminho na descoberta de novas drogas para fins terapêuticos. Em conclusão, sesquiterpenos presentes no óleo essencial de Copaifera langsdorffii Desf representam uma promissora fonte de obtenção de compostos terapêuticos para utilização contra o novo coronavírus e seus potenciais danos à saúde humana.
Quantum hydrogen vibrational dynamics in LiH: new neutron measurements and variational Monte Carlo simulations
Creators: name: Boronat, J.
name: Cazorla, C.
name: Colognesi, D.
name: Zoppi, M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Hydrogen single-particle dynamics in solid LiH at T=20 K has been studied through the incoherent inelastic neutron scattering technique. A careful analysis of the scattering data has allowed for the determination of a reliable hydrogen-projected density of phonon states and, from this, of three relevant physical quantities: mean squared displacement, mean kinetic energy, and Einstein frequency. In order to interpret these experimental findings, a fully-quantum microscopic calculation has been carried out using the variational Monte Carlo method. The agreement achieved between neutron scattering data and Monte Carlo estimates is good. In addition, a purely harmonic calculation has been also performed via the same Monte Carlo code, but anharmonic effects in H dynamics were not found relevant. The possible limitations of the present semi-empirical potentials are finally discussed.
description: RevTex, 19 pages, accepted for publication in PRB
COVID-19 identification in chest X-ray images on flat and hierarchical classification scenarios
Creators: name: Pereira, Rodolfo M.
name: Bertolini, Diego
name: Teixeira, Lucas O.
name: Silla, Carlos N.
name: Costa, Yandre M. G.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The COVID-19 can cause severe pneumonia and is estimated to have a high impact on the healthcare system. The standard image diagnosis tests for pneumonia are chest X-ray (CXR) and computed tomography (CT) scan. CXR are useful in because it is cheaper, faster and more widespread than CT. This study aims to identify pneumonia caused by COVID-19 from other types and also healthy lungs using only CXR images. In order to achieve the objectives, we have proposed a classification schema considering the multi-class and hierarchical perspectives, since pneumonia can be structured as a hierarchy. Given the natural data imbalance in this domain, we also proposed the use of resampling algorithms in order to re-balance the classes distribution. Our classification schema extract features using some well-known texture descriptors and also using a pre-trained CNN model. We also explored early and late fusion techniques in order to leverage the strength of multiple texture descriptors and base classifiers at once. To evaluate the approach, we composed a database, named RYDLS-20, containing CXR images of pneumonia caused by different pathogens as well as CXR images of healthy lungs. The classes distribution follows a real-world scenario in which some pathogens are more common than others. The proposed approach achieved a macro-avg F1-Score of 0.65 using a multi-class approach and a F1-Score of 0.89 for the COVID-19 identification in the hierarchical classification scenario. As far as we know, we achieved the best nominal rate obtained for COVID-19 identification in an unbalanced environment with more than three classes. We must also highlight the novel proposed hierarchical classification approach for this task, which considers the types of pneumonia caused by the different pathogens and lead us to the best COVID-19 recognition rate obtained here.
description: Accepted for publication in the Computer Methods and Programs in Biomedicine Journal
Intergenerational fairness from an economic perspective: Overview of some theoretical and methodological issues
Creators: name: Chybalski, Filip
name: Chybalski, Filip
Publisher: name: Unknown
Year: 2018
Subjects: subject: Labor and Human Capital
subject: Population
subject: ageing
subject: generation
subject: intergenerational fairness
subject: welfare
subject: efficiency

description: This paper seeks to conceptualize the term of intergenerational fairness with particular attention paid to possible comparative cross-country studies in this field that would aim at searching for the most efficient welfare policies serving for long-term equilibrium between generations in terms of well-being. According to the concept proposed, intergenerational fairness means such relations between different age groups which, in the context of given economic, political and demographic conditions, do not discriminate against any age group in terms of its present and future living situation. This includes present transfers (today) and their impact on prospects (future). Thus, intergenerational fairness cannot be measured only with reference to the contemporary situation, it must also account for the future.
Trade Policy Coordination and Food Price Volatility
Creators: name: Gouel, Christophe
name: Gouel, Christophe
Publisher: name: Unknown
Year: 2015
Subjects: subject: Demand and Price Analysis
subject: International Relations/Trade
subject: commodity price stabilization
subject: export restrictions
subject: repeated game
subject: WTO

description: Many countries adjust their trade policies countercyclically with food prices, to the extent that the use by numerous food exporters of export restrictions has occasionally threatened the food security of food importing countries. These trade policies are inconsistent with the terms-of-trade motivation often retained to characterize the payoff frontier of self-enforcing trade agreements, as they can worsen the terms of trade of the countries that apply them. This paper analyzes trade policy coordination when trade policies are driven by terms-of-trade effects and a desire to reduce domestic food price volatility. This framework implies that importing and exporting countries have incentives to deviate from cooperation at different periods: the latter when prices are high and the former when prices are low. Since staple food prices tend to have asymmetric distributions, with more prices below than above the mean but with occasional spikes, a self-enforcing agreement generates asymmetric outcomes. Without cooperation, an importing country uses more frequently its trade policy because of the concentration of prices below the mean, but an exporting country has a greater incentive to deviate from a cooperative trade policy because positive deviations from the mean price are larger than negative ones. Thus, the asymmetry of the distribution of commodity prices can make it more difficult to discipline export taxes than tariffs in trade agreements.
Efficiency and client satisfaction of Islamic and conventional banks: A bilateral effect
Creators: name: Aldeehani, Talla M
name: Aldeehani, Talla M
Publisher: name: Unknown
Year: 2018
Subjects: subject: Public Economics
subject: Bank efficiency
subject: Islamic banks
subject: customer satisfaction bilateral effects

description: In this paper, we investigate the possible bidirectional causal relationship between bank efficiency and client satisfaction in the banking sector of Kuwait. For this purpose, we applied structural equation model (SEM) methodology. Based on a 5-point Likert scale questionnaire, data was gathered from Islamic banks (IBs) clients and conventional banks (CBs) client. We found a significant evidence of a, relatively, higher client satisfaction for IBs. The findings, also, provide evidence of a positive and significant bilateral causal relationship between client satisfaction and bank efficiency. This is a result that confirms an anticipated theoretical proposition related to the ultimate goal of firm value maximization. Discussions, interpretations, implications, and recommendations are provided.