cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Free Phenolic Acids in Shanxi Aged Vinegar: Changes During Aging and Synergistic Antioxidant Activities
Creators: name: Hengye Chen
name: Youxiang Zhou
name: Yanchun Shao
name: Fusheng Chen
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Shanxi aged vinegar (SAV) is the most famous one among the four typical famous vinegars in China, which is produced by spontaneous solid-state fermentation using sorghum, bran, and millet chaff and Daqu. In this study, free phenolic acids (FPAs) species and changes during SAV aging, and the synergistic antioxidant activities between FPAs was investigated. The results revealed that eight FPAs, including protocatechuic acid, p-hydroxybenzoic acid, salicylic acid, dihydro sinapic acid, p-coumaric acid, sinapic acid, dihydro ferulic acid, and ferulic acid, stably existed during SAV 0–5 year aging periods, whereas during the aging time evaporation of water and FPAs combining with melanoidins made prediction of precise FPAs contents difficult. With regard to FPAs synergistic antioxidant activities, it was observed that the FPAs antioxidative interrelations were antagonism in antiradical activity experiments. And, only a few groups of FPAs mixtures showed antagonism in reduction experiments.
Enantioselective Synthesis of ((1R,2R)-Cyclohexane-1,2-diyl)bis(methylene)dimethanesulfonate, a Lurasidone Hydrochloride Intermediate
Creators: name: K. Ravi Ganesh
name: Pachore, Sharad S.
name: T. V. Pratap
name: K. Umesh
name: M. V. Basaveswara Rao
name: C. Murthy
name: M. Suresh Babu
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: A concise, economical, and highly enantioselective synthesis of bismesylate intermediate of lurasidone HCl, an antipsychotic, has been developed. The key steps involved in the synthesis are thionyl chloride–catalyzed esterification of tetrahydrophthalic anhydride in MeOH, epimerization of cis to trans isomer, hydrolysis of the diester, resolution of the diacid, reduction with Red-Al, and finally bismesylation of the corresponding diol, which provided the desired intermediate ((1 R,2 R)-cyclohexane-1,2-diyl)bis(methylene) dimethanesulfonate in overall good yield.
The Australian Football League’s social agenda
Creators: name: Gill, Robert
Publisher: name: Swinburne
Year: 2024

description: National sport codes are in the position of being leaders for upholding and promoting social responsibility values, due to their engagement with the public and media commentary. Sport is ideally placed to be lead awareness for social issues, particularly around equality and inclusion. In Australia, the biggest national sport code is the Australian Football League (AFL) governed by its Commission. The AFL Commission is very aware of its ability to lead social discussion and drive policy around many community issues and challenges. The code at its professional level has evolved from a localism culture to a ‘commodified sport’, characterised by high-level business objectives, technology and sport elitism. The code has a strong emphasis on brand and reputation resulting in advanced professionalism and commercialisation. The Commission endeavours to protect its brand, and appears well aware of the importance of ‘social responsibility positioning’ in order to manage and enhance its brand. This paper looks at the social agenda the AFL promotes and analyses its positions against Organisational – Public Relationship theory to understand if the AFL motive is for commercial branding or is for contributing to the greater good in the communities it AFL operates in. This case study reviews the social agendas the AFL promotes through its media and community presence. The case study approach of comparing the analysed media and policy output from the AFL against contemporary academic literature on social responsibility will aid sports organisations in developing their strategic communication.
Free phenolic acids in Shanxi aged vinegar: changes during aging and synergistic antioxidant activities
Creators: name: Yanchun Shao
name: Fusheng Chen
name: Hengye Chen
name: Youxiang Zhou
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Developmental Biology
Biological Sciences
Chemistry
Earth and Environmental Sciences
Neuroscience
Medicine
Biochemistry

description: ABSTRACTShanxi aged vinegar (SAV) is the most famous one among the four typical famous vinegars in China, which is produced by spontaneous solid-state fermentation using sorghum, bran and millet chaff and Daqu. In this study, free phenolic acids (FPAs) species and changes during SAV aging, and the synergistic antioxidant activities between FPAs was investigated. The results revealed that 8 FPAs, including protocatechuic acid, p-hydroxybenzoic acid, salicylic acid, dihydro sinapic acid, p-coumaric acid, sinapic acid, dihydro ferulic acid and ferulic acid, stably existed during SAV 0-5 year aging periods, whereas during the aging time evaporation of water and FPAs combining with melanoidins made prediction of precise FPAs contents difficult. With regard to FPAs synergistic antioxidant activities, it was observed that the FPAs antioxidative interrelations were antagonism in antiradical activity experiments. And, only a few groups showed antagonism in reduction experiments.
Photocatalytic Degradation of Malachite Green by Magnetic Photocatalyst
Creators: name: Farhadian, Mousa
name: Kazemzad, Mahmood
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Cancer
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Molecular Biology

description: Magnetic photocatalyst nanoparticles with the nanocomposite structures of Fe3O4@TiO2 (FT) and Fe3O4@SiO2@TiO2 (FST) have been prepared by applications of different wet chemical procedures. Various characterization techniques have been utilized to confirm the formation of the core-shell nanoparticles. Then, studying the kinetics of photocatalytic degradation of malachite green (MG) by prepared samples showed that FST sample has superior photocatalytic activity than FT samples. Investigation of the recyclability of prepared samples showed that the high degradation efficiency of 87% could be obtained by the prepared FST nanoparticles after five cycles of utilization.
GN5-1 Status of Cyber Security Awareness within National Research and Education Networks
Creators: name: Luyten, Davina
name: van Genuchten, Charlie
name: Norman, Rosanna
name: Tysom, Mark
name: Dimić Vugec, Marina
Publisher: name: GÉANT
Year: 2024
Subjects: WP8
Security
Human Factor

description: This report describes the outcomes of a survey conducted by GN5-1 Work Package 8, Task 2 Human Factor (WP8 T2), subtask Awareness, on the status of cyber security awareness within the National Research and Education Networks.
Cysteine-Functionalized Chitosan Magnetic Nano-Based Particles for the Recovery of Uranium (VI): Uptake Kinetics and Sorption Isotherms
Creators: name: Galhoum, Ahmed A.
name: Mahfouz, Mohammad G.
name: Nabawia A. Gomaa
name: Abdel-Rehem, Sayed S.
name: Asem A. Atia
name: Vincent, Thierry
name: Guibal, Eric
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: Medicine
subject: Physics
subject: Biochemistry
subject: Biophysics

description: Magnetic-chitosan nanoparticles, functionalized with cysteine, were synthesized and characterized by element analysis, FT-IR, XRD, TEM, and vibrating sample magnetometry. The sorbent was tested for U(VI) recovery, considering: (a) pH effect, (b) sorption isotherms (fitted by Langmuir equation), and (c) uptake kinetics (modeled using the PSORE Maximum sorption capacity approached 100 mg U g−1. The nanometric size of sorbent reduces the impact of resistance to intraparticle diffusion; this may explain the fast kinetics (equilibrium within 50 min). The reaction is exothermic, spontaneous. The metal could be desorbed using acidified urea solution and the sorbent could be recycled for 5 cycles.
24-hour pattern of falls in hospitalized and long-term care institutionalized elderly persons: A systematic review of the published literature
Creators: name: López-Soto, Pablo Jesús
name: Manfredini, Roberto
name: Smolensky, Michael H.
name: Rodríguez-Borrego, María Aurora
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biotechnology
subject: Neuroscience
subject: Genetics
subject: FOS: Biological sciences
subject: Medicine

description: Falls are common among the elderly > 65 years of age and can result in both serious trauma and costly medical care. The epidemiology of falls in the elderly typically focuses on identifying contributory exogenous environmental and endogenous age-related physical, cognitive and other health status factors; however, one potentially important variable seldom considered is time of fall. We sought to determine if falls in hospitalized/institutionalized elderly persons exhibit 24 h and other temporal patterns, since knowledge of such could be useful in their prevention. We conducted a systematic review of the published literature to critically appraise and synthesize the methods and findings of previous reports addressing clock-time, day-of-week and month-of-year fall patterns of institutionalized elderly cohorts. Medline, SCOPUS, Ovid SP and Web of Knowledge were systematic assessed, entering search terms of “accidental fall”, “circadian rhythm”, “biological clocks”, “circadian clocks”, “activity cycles”, “periodicity”, and with databases accepting an age limiter, “age of 65+ years”. Methodological quality was assessed by STROBE and CONSORT checklists, respectively, in observational and clinical studies. Publications were reviewed if meeting inclusion criteria of: (i) being an empirical study, (ii) adopting circadian and/or other period rhythmicity as a fall risk, and (iii) focusing on hospitalized/institutionalized falls in those ≥ 65 years of age; plus exclusion criteria of: (i) cohort
An Enantioselective Synthesis of ((1R,2R)-Cyclohexane-1,2-diyl)bis(methylene)dimethanesulfonate, a Lurasidone Hydrochloride Intermediate
Creators: name: K. Ravi Ganesh
name: Pachore, Sharad S.
name: T. V. Pratap
name: K. Umesh
name: M. V. Basaveswara Rao
name: C. Murthy
name: M. Suresh Babu
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: :A concise, economical and highly enantioselective synthesis of bis mesylate intermediate of Lurasidone HCl, an antipsychotic has been developed. The key steps involved in the synthesis are, thionyl chloride catalyzed esterification of tetrahydro phthalic anhydride in MeOH, epimerization of cis to trans isomer, hydrolysis of the di ester, resolution of the di acid, reduction with Red-Al and finally bis mesylation of the corresponding diol provided the desired intermediate ((1 R,2 R)-cyclohexane-1,2-diyl)bis(methylene) dimethanesulfonate in overall good yield.
Independent association between symptom onset time and infarct size in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention
Creators: name: Wieringa, Wouter G.
name: Hillege, Hans L.
name: Mahmoud, Karim D.
name: Nijsten, Maarten W.
name: Ottervanger, Jan P.
name: Holmes, David R.
name: Arnoud W. Van 'T Hof
name: Lipsic, Erik
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Genetics
subject: Biochemistry

description: Recent studies have reported on circadian variation in infarct size in ST-elevation myocardial infarction (STEMI) patients. Controversy remains as to whether this finding indicates circadian dependence of myocardial tolerance to ischemia/reperfusion injury or that it can simply be explained by confounding factors such as baseline profile and ischemic time. We assessed the clinical impact and independent association between symptom onset time and infarct size, accounting for possible subgroup differences. From a multicenter registry, 6799 consecutive STEMI patients undergoing primary percutaneous coronary intervention (PCI) between 2004 and 2010 were included. Infarct size was measured using peak creatine kinase (CK). Infarct size exhibited circadian variation with largest infarct size in patients with symptom onset around 03:00 at night (estimated peak CK 1322 U/l; 95% confidence interval (CI): 1217–1436) and smallest infarct size around 11:00 in the morning (estimated peak CK 1071 U/l; 95% CI: 1001–1146; relative reduction 19%; p = 0.001). Circadian variation in infarct size followed an inverse pattern in patients with prior myocardial infarction (p-interaction <0.001) and prior PCI (p-interaction = 0.006), although the later did not persist in multivariable analysis. Symptom onset time remained associated with infarct size after accounting for these interactions and adjusting for baseline characteristics and ischemic time. Symptom onset time did not predict one-year mortality (p = 0.081). In conclusion, there is substantial circadian variation in infarct size, which cannot be fully explained by variations in baseline profile or ischemic time. Our results lend support to the hypothesis of circadian myocardial ischemic tolerance and suggest a different mechanism in patients with prior myocardial infarction.
Blockchains, Orphan Works, and the Public Domain
Creators: name: Goldenfein, Jake
name: Hunter, Dan
Publisher: name: Swinburne
Year: 2024

description: This Article outlines a blockchain based system to solve the orphan works problem. Orphan works are works still ostensibly protected by copyright for which an author cannot be found. Orphan works represent a significant problem for the efficient dissemination of knowledge, since users cannot license the works, and as a result may choose not to use them. Our proposal uses a blockchain to register attempts to find the authors of orphan works, and otherwise to facilitate use of those works.
There are three elements to our proposal. First, we propose a number of mechanisms, included automated systems, to perform a diligent search for a rights holder. Second, we propose a blockchain register where every search for a work’s owner can be recorded. Third, we propose a legal mechanism that delivers works into orphanhood, and affords a right to use those works after a search for a rights holder is deemed diligent. These changes would provide any user of an orphan work with an assurance that they were acting legally as long as they had consulted the register and/or performed a diligent search for the work’s owner.
The Article demonstrates a range of complementary legal and technological architectures that, in various formations, can be deployed to address the orphan works problem. We show that these technological systems are useful for enhancement of the public domain more generally, through the existence of a growing registry of gray status works and clarified conditions for their use. The selection and design of any particular implementation is a choice for policy makers and technologists. Rather than specify how that choice should look, the goal here is to demonstrate the utility of the technology and to clarify and promote its role in reforming this vexed area of law.
Negligible respiratory irritation and inflammation potency of pigmentary TiO2 in mice
Creators: name: Lehto, Maili
name: Wolff, Henrik
name: Veli-Matti Kosma
name: Alenius, Harri
name: Leppänen, Maija
name: Korpi, Anne
name: Yli-Pirilä, Pasi
name: Pasanen, Pertti
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Cell Biology
subject: Microbiology
subject: Medicine
subject: Biochemistry

description: Titanium dioxide (TiO2) is manufactured in millions of tons yearly, and it is used widely as pigment in various applications. Until recently, TiO2 was considered toxicologically harmless and without adverse health effects. In this study, respiratory irritation and inflammation potencies of commercially available pigmentary TiO2 particles (<5 µm, rutile) were studied. Single head-only exposures (30 min) of male Crl:OF1 mice at mass concentrations 6, 11, 21, and 37 mg/m3, and repeated exposures (altogether 16 h, 1 h/day, 4 days/week for 4 weeks) of female BALB/c/Sca mice at mass concentration of 16 mg/m3 to pigmentary TiO2 were conducted. Minor sensory irritation was observed during acute and repeated exposures seen as elongation of the break after the inhalation, which is typical in sensory irritation, and caused by closure of the glottis inhibiting airflow from the lungs after inspiration. No pulmonary irritation, airflow limitation, nasal or pulmonary inflammation was observed. In conclusion, the respiratory irritation and inflammation potencies of the studied pigmentary TiO2 particles seemed to be low and thus can serve as an ideal control exposure agent in short-term studies in mice.
title: Politique de dépôt dans la communauté REL Bib-CP Zenodo des universités universités québécoises (Université Laval)
title: Politique spécifique pour Université Laval, bibliothèque et centres de soutien à l'enseignement
titleType: Subtitle
Creators: name: Bibliothèque de l'Université Laval
Publisher: name: Université Laval
Year: 2024
Subjects: Ressources éducatives libres
Publications en libre accès

description: Cette politique énonce les éléments à respecter lors d'un dépôt dans la communauté REL Bib-CP des universités québécoises de Zenodo pour les employées de la bibliothèque et des centres de soutien à l'enseignement à l'Université Laval. Elle est complémentaire à la politique de base de la communauté, disponible dans le document Traitement des dépôts de REL dans la communauté REL Bib-CP Zenodo.
description: Ressources éducatives libres

REL

Open educational resources

OER
description: Discipline : Éducation

Format : Texte/HTML

Type de la ressource : Objet d'apprentissage

Type de matériel pédagogique : Guide
Photocatalytic degradation of malachite green by magnetic photocatalyst
Creators: name: Farhadian, Mousa
name: Kazemzad, Mahmood
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Cancer
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Molecular Biology

description: Magnetic photocatalyst nanoparticles with the nanocomposite structures of Fe3O4@TiO2 (FT) and Fe3O4@SiO2@TiO2 (FST) have been prepared by applications of different wet chemical procedures. Various characterization techniques have been utilized to confirm the formation of the core-shell nanoparticles. Then, Studying the kinetics of photocatalytic degradation of malachite green (MG) by prepared samples showed that FST sample has superior photocatalytic activity than FT samples. Investigation of the recyclability of prepared samples showed that the high degradation efficiency of 87% could be obtained by the prepared FST nanoparticles after 5 cycles of utilization.
Glial and light-dependent glutamate metabolism in the suprachiasmatic nuclei
Creators: name: M. J. Leone
name: C. Beaule
name: L. Marpegan
name: T. Simon
name: E. D. Herzog
name: D. A. Golombek
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Molecular Biology
subject: Genetics
subject: Cell Biology

description: The suprachiasmatic nuclei, the main circadian clock in mammals, are entrained by light through glutamate released from retinal cells. Astrocytes are key players in glutamate metabolism but their role in the entrainment process is unknown. We studied the time dependence of glutamate uptake and glutamine synthetase (GS) activity finding diurnal oscillations in glutamate uptake (high levels during the light phase) and daily and circadian fluctuations in GS activity (higher during the light phase and the subjective day). These results show that glutamate-related astroglial processes exhibit diurnal and circadian variations, which could affect photic entrainment of the circadian system.
Influence of ultrasonic dual mode mixing on the morphology, molecular structure and thermo-physical properties of a SiO2-epoxy nanocomposite adhesive
Creators: name: Halder, Sudipta
name: M.S. Goyat
name: P.K. Ghosh
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Medicine
subject: Physics
subject: Engineering
subject: Biophysics

description: Silica nanoparticles (~15 nm) were introduced in an epoxy adhesive using an ultrasonic dual mode mixing route at different amplitudes to tune the thermo-physical properties. Processing at higher amplitude resulted in a homogeneous distribution of less clustered nanoparticles. Glass transition temperature, thermal stability, and activation energy of nanocomposites processed at 55% of amplitude showed a significant enhancement for a very low nanoparticle content of 0.5 wt%. Incorporation of a higher nanoparticle content from 2 to 5 wt% declines the properties of the composite possibly due to increasing the number of clusters rather than the cluster size which may adversely affect the cross-linking density of the base polymer.
One-Pot Synthesis of Pyrazole Ring Attached Novel Thiosemicarbazone Derivatives
Creators: name: İrfan Koca
name: Gümüş, Mehmet
name: Gökbaş, Latif
name: Er, Muhammet
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology

description: GRAPHICAL ABSTRACT
Talking about security with professional developers
Creators: name: Lopez, Tamara
name: Sharp, Helen
name: Tun, Thein
name: Bandara, Arosha
name: Levine, Mark
name: Nuseibeh, Bashar
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 4612
subject: Software engineering

description: This paper describes materials developed to engage professional developers in discussions about security. First, the work is framed in the context of ethnographic studies of software development, highlighting how the method is used to explore and investigate research aims for the Motivating Jenny research project. A description is given of a series of practitioner engage?ments, that were used to develop a reflection and discussion tool using security stories taken from media and internet sources. An explanation is given for how the tool has been used to collect data within field sites, offering a way to clarify and member check findings, and to provide a different view on practice and process.The report concludes with observations and notes about future aims for supporting and encouraging professionals to engage with security in practice.
GN5-1 M7.4 Example Workflow Orchestrator with IMS and IPAM Integration
Creators: name: Trompert, Hans
Publisher: name: GÉANT
Year: 2023

description: A set of best common practices is explained using an orchestrator implementation based on the open source Workflow Orchestrator.  A basic set of NREN products and workflow are modelled for a Node, Core Link, Customer port and L2VPN service, together with an IMS and IPAM integration using NetBox.
Analysis of gene expression identifies candidate markers and pathways in pre-eclampsia
Creators: name: P. He
name: D. Shao
name: M. Ye
name: G. Zhang
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Biological Sciences
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Microbiology
subject: Biochemistry

description: Pre-eclampsia is a serious multisystem disorder and causes significant increase in both maternal and foetal morbidity and perinatal mortality globally. Due to the limited understanding of the molecular mechanism of pre-eclampsia, the current study conducted bioinformatic analyses to screen key regulators involved in pre-eclampsia. The gene expression profiling dataset GSE44711 containing 8 early-onset pre-eclampsia placentas and 8 gestational-age-matched control placentas was downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) were screened by limma software package, which were then subjected to Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analysis on the Database for Annotation, Visualization, and Integrated Discovery website. Finally, protein–protein interaction network was constructed using the Search Tool for the Retrieval of Interacting Genes database. In total, 192 DEGs including 106 upregulated and 86 downregulated genes were obtained. Proteoglycan 2 and podoplanin were the most significantly up- and downregulated genes, respectively. In addition, three potential pathways and their related DEGs: spermidine/spermine N1-acetyltransferase 1, amiloride-binding protein 1 and adenosylmethionine decarboxylase 1 were associated with arginine and proline metabolism. Vascular endothelial growth factor C; phosphatidylinositol-4, 5-bisphosphate 3-kinase, catalytic subunit beta; collagen, type I, alpha 1 (COL1A1); and fibronectin 1 (FN1) were associated with focal adhesion. COL6A1 as well as COL1A1 and FN1 were involved in extra-cellular matrix–receptor interaction. The current study identified several potential genes and three pathways which may be considered as candidate targets for diagnosis and therapy of pre-eclampsia.
Copolymers enhance selective bacterial community colonization for potential root zone applications
Creators: name: Pham, Vy
name: Murugaraj, Pandiyan
name: Mathes, Falko
name: Tan, Boon K.
name: Truong, Vi Khanh
name: Murphy, Daniel V.
name: Mainwaring, David
Publisher: name: Swinburne
Year: 2024

description: Managing the impact of anthropogenic and climate induced stress on plant growth remains a challenge. Here we show that polymeric hydrogels, which maintain their hydrous state, can be designed to exploit functional interactions with soil microorganisms. This microbial enhancement may mitigate biotic and abiotic stresses limiting productivity. The presence of mannan chains within synthetic polyacrylic acid (PAA) enhanced the dynamics and selectivity of bacterial ingress in model microbial systems and soil microcosms. Pseudomonas fluorescens exhibiting high mannan binding adhesins showed higher ingress and localised microcolonies throughout the polymeric network. In contrast, ingress of Bacillus subtilis, lacking adhesins, was unaltered by mannan showing motility comparable to bulk liquids. Incubation within microcosms of an agricultural soil yielded hydrogel populations significantly increased from the corresponding soil. Bacterial diversity was markedly higher in mannan containing hydrogels compared to both control polymer and soil, indicating enhanced selectivity towards microbial families that contain plant beneficial species. Here we propose functional polymers applied to the potential root zone which can positively influence rhizobacteria colonization and potentially plant growth as a new approach to stress tolerance.
title: Modelling and Simulation of Building Material Flows: Assessing the Potential for Concrete Recycling in the German Construction Sector
Creators: name: Mostert, Clemens
name: Weber, Christian
name: Bringezu, Stefan
Publisher: name: Universität Kassel
Year: 2022
Subjects: subject: concrete recycling
subject: mineral construction waste
subject: recycled aggregates
subject: building material flows
subject: residential buildings stock
subject: urban mining
subject: system dynamics
subject: 620
subject: 710
subject: Beton
subject: Recycling
subject: Bauschutt
subject: Baustoff
subject: Wohnungsbestand
subject: Urban Mining
subject: System Dynamics

description: Gefördert durch den Publikationsfonds der Universität Kassel
Synthesis and Surface Characterization Studies of Polyether-Linked Symmetric Higher Sulfanyl-1,3,4-Oxadiazoles
Creators: name: A. Yıldırım
name: S. Öztürk
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences

description: GRAPHICAL ABSTRACT
Analysis of gene expression identifies candidate markers and pathways in pre-eclampsia
Creators: name: P. He
name: D. Shao
name: M. Ye
name: G. Zhang
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Microbiology
subject: Biochemistry

description: Pre-eclampsia is a serious multisystem disorder and causes significant increase in both maternal and foetal morbidity and perinatal mortality globally. Due to the limited understanding of the molecular mechanism of pre-eclampsia, the current study conducted bioinformatic analyses to screen key regulators involved in pre-eclampsia. The gene expression profiling dataset GSE44711 containing 8 early-onset pre-eclampsia placentas and 8 gestational-age-matched control placentas was downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) were screened by limma software package, which were then subjected to Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analysis on the Database for Annotation, Visualization, and Integrated Discovery website. Finally, protein–protein interaction network was constructed using the Search Tool for the Retrieval of Interacting Genes database. In total, 192 DEGs including 106 upregulated and 86 downregulated genes were obtained. Proteoglycan 2 and podoplanin were the most significantly up- and downregulated genes, respectively. In addition, three potential pathways and their related DEGs: spermidine/spermine N1-acetyltransferase 1, amiloride-binding protein 1 and adenosylmethionine decarboxylase 1 were associated with arginine and proline metabolism. Vascular endothelial growth factor C; phosphatidylinositol-4, 5-bisphosphate 3-kinase, catalytic subunit beta; collagen, type I, alpha 1 (COL1A1); and fibronectin 1 (FN1) were associated with focal adhesion. COL6A1 as well as COL1A1 and FN1 were involved in extra-cellular matrix–receptor interaction. The current study identified several potential genes and three pathways which may be considered as candidate targets for diagnosis and therapy of pre-eclampsia.
Surgical interventions for nephrolithiasis in ankylosing spondylitis and the general population
Creators: name: Jakobsen, Ane Krag
name: L. T. H. Jacobsson
name: O. Patschan
name: T. Hopfgarten
name: J. Askling
name: L. E. Kristensen
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Marine Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Earth and Environmental Sciences
subject: Medicine

description: Objective. The aim of this study was to estimate rates and type of definitive surgical interventions for nephrolithiasis in Swedish patients with ankylosing spondylitis (AS) compared to the general population. Materials and methods. This national prospective cohort study linked data from Swedish population and healthcare registries. Incidence rates and interventions for nephrolithiasis during follow-up in patients with AS were compared to general population comparator (GPC) subjects. Results. In total, 8572 AS patients were followed for 49,959 person-years and 39,639 matched GPCs were followed for 225,221 person-years. Mean age at study entry was 46 years [interquartile range (IQR) 36–56 years] and 65% were male. In AS patients with a diagnosis of nephrolithiasis during the study period, 29% (72/250) underwent similar intervention for nephrolithiasis compared to 24% (114/466) GPCs (p = 0.21). The incidence rate ratio (RR) in overall AS patients was 2.9 [95% confidence interval (CI) 2.1–3.8] during a median follow-up of 6.2 years (IQR 3.2–8.6 years). With prior diagnosis of nephrolithiasis, the RR for AS patients compared to GPCs was 3.7 (95% CI 1.8–7.7); without prior nephrolithiasis the RR was 2.1 (95% CI 1.5–3.0). Increasing age [odds ratio (OR) 1.02, 95% CI 1.01–1.03], prior nephrolithiasis diagnosis (OR 3.3, 95% CI 1.97–5.62) and atherosclerotic cardiac disease (OR 2.0, 95% CI 1.03–3.91) were identified as predictors of intervention for nephrolithiasis. Conclusions. Patients with AS have an almost three-fold increased risk of surgical intervention for kidney stones, with similar management, compared to the general population.
Inhibition of cell proliferation, invasion and migration by the cardenolides digitoxigenin monodigitoxoside and convallatoxin in human lung cancer cell line
Creators: name: Kreis, Wolfgang
name: Braga, Fernão C.
name: Simões, Cláudia M. O.
name: Schneider, Naira F. Z.
name: Geller, Fabiana C.
name: Persich, Lara
name: Marostica, Lucas L.
name: Pádua, Rodrigo M.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Developmental Biology
Biological Sciences
Chemistry
Pharmacology
Cell Biology
Biochemistry

description: Cardiac glycosides consist of a large family of naturally derived compounds that are clinically used to treat congestive heart failure, and also present anticancer properties. In this study, the cytotoxic effects of two cardenolides, digitoxigenin monodigitoxoside (DGX) and convallatoxin (CON) were screened in four human tumour cell lines. Both compounds showed anti-proliferative effects in all tumour cells, at nanomolar concentrations. Since the human lung cancer cell line A549 was the most sensitive, we investigated the anti-proliferative, anti-migratory and anti-invasive effects of these cardenolides. DGX and CON reduced A549 cell migration, being able to reduce more than 90% of cell invasion. Their effects on the expression of key regulators of metastatic mechanism showed decreased levels of MMP-2, MMP-9 and p-FAK. Both compounds also presented low toxicity for healthy cells. Finally, this work provides the first insights into the effects of these cardenolides on key steps of lung cancer metastasis.
The What, Who, How & Why: Building interpretive support models for the design of pediatric health education materials
Creators: name: Wahlin, Willhemina
name: Paulovich, Belinda
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 3303
subject: Design

description: Designing information for pediatric health education that is easily interpreted by patients is complicated by factors including attitudes and complex power relationships. This study examines such factors in relation to three pediatric health education case studies on asthma management, chronic functional constipation and rehabilitation. They emphasize direct communication with pediatric patients with a view to increasing patient empowerment. Strategic graphic design is employed in collaboration with clinicians to create multimodal semiotic resources. This paper examines these cases within Wahlin’s CHaSSMM Model (Wahlin 2015), which combines social semiotics with multimodality and critical hermeneutics. CHaSSMM’s potential is making explicit the project’s underlying power structures and meaning potential of multimodal, semiotic resources. It begins with an overview of the pediatric health education case studies and the CHaSSMM Model of analysis, and then explains how CHaSSMM can provide support for the planning and interpretive stages of design projects.
Safety climate of ab-initio flying training organizations: the case of an Australian tertiary (collegiate) aviation program
Creators: name: Gao, Yi
name: Rajendran, Natalia
Publisher: name: Swinburne
Year: 2024

description: A healthy safety culture is essential to the safe operation of any aviation organization, including flight schools. This study aimed to assess the safety climate of an Australian tertiary (collegiate) aviation program using a self-constructed instrument. Factor analysis of the instrument identified four safety themes, which are Safety Reporting Culture, Safety Reporting Procedure, Organizational Culture and Practice, and General Safety Knowledge. The responses of student pilots suggested that the overall safety climate of the subject flight training academy was healthy at the time of the survey. Further analyses found that perceptions of students of different year groups on Reporting Culture and Organizational Culture and Practices were significantly different from each other, with the first-year students responding more positively. Besides addressing the safety climate of the subject flight training academy, this study also provided a template and a benchmark for other tertiary (collegiate) aviation programs to assess their own safety climate.
M&E-NetPay: A micropayment system for mobile and electronic commerce
Creators: name: Huang, Xiaodi
name: Bao, Jinsong
name: Dai, Xiaoling
name: Singh, Edwin
name: Huang, Weidong
name: Huang, Changqin
Publisher: name: Swinburne
Year: 2024

description: As an increasing number of people purchase goods and services online, micropayment systems are becoming particularly important for mobile and electronic commerce. We have designed and developed such a system called M&E-NetPay (Mobile and Electronic NetPay). With open interoperability and mobility, M&E-NetPay uses web services to connect brokers and vendors, providing secure, flexible and reliable credit services over the Internet. In particular, M&E-NetPay makes use of a secure, inexpensive and debit-based off-line protocol that allows vendors to interact only with customers, after validating coins. The design of the architecture and protocol of M&E-NetPay are presented, together with the implementation of its prototype in ringtone and wallpaper sites. To validate our system, we have conducted its evaluations on performance, usability and heuristics. Furthermore, we compare our system to the CORBA-based (Common Object Request Broker Architecture) off-line micro-payment systems. The results have demonstrated that M&E-NetPay outperforms the .NET-based M&E-NetPay system in terms of performance and user satisfaction.
GN5-1 M7.3 Common NREN Network Service Product Models
Creators: name: Trompert, Hans
Publisher: name: GÉANT
Year: 2023

description: This document describes a set of network service product models that are common to the NREN community and can be used in combination with the Workflow Orchestrator. Models for a node, port, L2 point-to-point service, L2 VPN service, and IP static service, are presented, along with descriptions of how the model building blocks can be extended and re-used.
Risk factors Associated prolonged stay in stabilization center among 6-59 Months children with severe acute malnutrition at selected hospital, Mogadishu-Somalia, 2023
Creators: name: Deko, Ali Hussein
Publisher: name: Zenodo
Year: 2025
Subjects: Risk factors Associated prolonged
stabilization center among 6-59 Months children
severe acute malnutrition at selected hospital, Mogadishu-Somalia, 2023

description:                            ABSTRACT

Introduction:   Malnutrition, defined as underweight, is a serious public-health problem that has been linked to a substantial increase in the risk of mortality and morbidity. Women and young children bear the brunt of the disease burden associated with malnutrition.
Helping hands: using augmented reality to provide remote guidance to health professionals
Creators: name: Mather, Carey
name: Barnett, Tony
name: Broucek, Vlasti
name: Saunders, Annette
name: Grattidge, Darren
name: Huang, Weidong
Publisher: name: Swinburne
Year: 2024

description: Access to expert practitioners or geographic distance can compound the capacity for appropriate supervision of health professionals in the workplace. Guidance and support of clinicians and students to undertake new or infrequent procedures can be resource intensive. The Helping Hands remote augmented reality system is an innovation to support the development of, and oversee the acquisition of procedural skills through remote learning and teaching supervision while in clinical practice. Helping Hands is a wearable, portable, hands-free, low cost system comprised of two networked laptops, a head-mounted display worn by the recipient and a display screen used remotely by the instructor. Hand hygiene was used as the test procedure as it is a foundation skill learned by all health profession students. The technology supports unmediated remote gesture guidance by augmenting the object with the Helping Hands of a health professional. A laboratory-based study and field trial tested usability and feasibility of the remote guidance system. The study found the Helping Hands system did not compromise learning outcomes. This innovation has the potential to transform remote learning and teaching supervision by enabling health professionals and students opportunities to develop and improve their procedural performance at the workplace.
The surficial geology of the Delta 7.5-minute series quadrangle, Fulton County, Ohio, USA
Creators: name: Blockland, Joseph D.
name: Fisher, Timothy G.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The surficial geology of the Delta 7.5-minute series quadrangle, and sections of the adjacent quadrangles (ca. 54.5 km2), was mapped to elucidate the deglacial history of the Huron–Erie Lake Plain in northwest Ohio. Five depositional environments were identified: alluvial, aeolian, glacial, glaciolacustrine and glaciofluvial. The depositional environments were mapped on a hillshaded, light detecting and ranging digital elevation model using a sediment-landform approach. Map interpretations were field tested with borings, shallow pits, electrical resistivity and ground-penetrating radar surveys. Four prominent strandlines of Ancestral Lake Erie trend NNE to SSW across the study area at 238, 231, 224 and 221 m above sea level and are comprised of offshore bars, possible beaches and spits recording littoral drift from the NNE. This study emphasizes the importance of large-scale mapping and provides a framework for subsequent research in the region.
Assessment and Analysis of Workplace Violence in a Greek Tertiary Hospital
Creators: name: Mantzouranis, George
name: Fafliora, Eleftheria
name: Bampalis, Vasileios G.
name: Christopoulou, Ioanna
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Biological Sciences
Biotechnology

description: This study sought to assess workplace violence in a Greek tertiary hospital for the first time. The authors conducted a descriptive study with 175 participants and examined the characteristics of violent episodes, the responses of victims and the administration, and the perception of workplace safety in addition to the implications of these incidents. The vast majority of employees (83.4%) had experienced work-related violence; however, half of them (52%) had not reported the incident to the hospital administration. Verbal violence was the most common type of incident (98.6%). Nurses and other health care staff reported feeling safer than physicians (odds ratio [OR] = 4.47, 95% confidence interval [CI]: 1.94–10.28 and OR = 2.80, 95% CI: 1.64–8.74, respectively). A large proportion of victims (72.6%) suffered psychological consequences following the violent incident. This study reveals the high prevalence of workplace violence in a Greek tertiary hospital and underscores its negative impact on health care workers.
Retinal Histopathology in Eyes from a Patient with Stargardt disease caused by Compound Heterozygous ABCA4 Mutations*
Creators: name: Bonilha, Vera L.
name: Rayborn, Mary E.
name: Bell, Brent A.
name: Marino, Meghan J.
name: Fishman, Gerald A.
name: Hollyfield, Joe G.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Developmental Biology
subject: Computational Biology

description: Background: The goal of this study was to define the histopathology of the retina in donor eyes from a patient with Stargardt disease (STGD1) due to compound mutations in the ABCA4 gene. Materials and Methods: Eyes were obtained from a 66-year-old female and fixed within 18 hours postmortem. The fundi of the posterior globes were evaluated with macroscopic, SLO and OCT imaging. The perifoveal and peripheral regions were processed for electron microscopy and immunocytochemistry using cell specific antibodies. Two age-similar normal eyes were used as controls. Prior ophthalmic examinations and genetic test results were also reviewed. Results: All imaging modalities showed scattered bone spicules in the peripheral retina. Atrophy of the RPE was present around the optic nerve as evidenced by the absence of SLO autofluorescence. Histology analysis showed a severely degenerated fovea with little evidence of any retinal layering or remaining RPE. The fovea was severely degenerated, with little evidence of any retinal cell layer, including the RPE. In contrast, retinal nuclear layers were present in the periphery. The perifoveal region contained few cones labeled with cone-specific antibodies; some rhodopsin-labeled cells, reactive glia labeled with GFAP; and decreased autofluorescence of the RPE. The fovea was free of cone-specific labeling, contained a few disorganized rhodopsin-labeled cells and showed substantial GFAP labeling and no autofluorescent material in the retina. The periphery displayed stubby cells labeled with cone-specific antibodies, decreased rhodopsin-labeled cells, increased GFAP staining, and autofluorescent granules in the RPE. Conclusions: The histopathology of the retina in this patient with Stargardt disease displayed a highly degenerated fovea. In all retinal locations studied, cones were more severely affected than rods.