cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Electromagnetic Effective Degree of Freedom of a MIMO System in Free Space
Creators: name: Yuan, Shuai S. A.
name: He, Zi
name: Chen, Xiaoming
name: Huang, Chongwen
name: Sha, Wei E. I.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Information Theory (cs.IT)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Effective degree of freedom (EDOF) of a multiple-input-multiple-output (MIMO) system represents its equivalent number of independent single-input-single-output (SISO) systems, which directly characterizes the communication performance. Traditional EDOF only considers single polarization, where the full polarized components degrade into two independent transverse components under the far-field approximation. However, the traditional model is not applicable to complex scenarios especially for the near-field region. Based on an electromagnetic (EM) channel model built from the dyadic Green's function, we first calculate the EM EDOF to estimate the performance of an arbitrary MIMO system with full polarizations in free space. Then, we clarify the relations between the limit of EDOF and the optimal number of sources/receivers. Finally, potential benefits of near-field MIMO communications are demonstrated with the EM EDOF, in which the contribution of the longitudinally polarized source is taken into account. This work establishes a fundamental EM framework for MIMO wireless communications.
description: 5 pages, 5 figures
Munqidh Min Al Dalal and the Question of “Prophecy” – A Comparative Analysis of the Position of Muslim Philosophers and Al-Ghazali
Creators: name: Khan, Muhammad
Publisher: name: figshare
Year: 2021
Subjects: subject: 220402 Comparative Religious Studies
subject: FOS: Philosophy, ethics and religion

description: This essay explores Al-Ghazali’s response to the position of the falasafa (philosophers) on the nature of prophecy in the Munqidh min al dalal (Deliverance from Error). Munqidh is an autobiographical account of Al-Ghazali’s journey as a seeker of truth who explores different schools of Islamic thought to attain the true path. In this work he defends the orthodox conception of the prophet as a man endowed with a spiritual authority among the faithful, a divine scripture and a mission to invite the transgressors towards the right path. The falasafa distorted this view to rationalize prophecy as an intellectual experience of the prophet. The article underlines the position of Al-Farabi and Avicenna to present a case for the philosophers, and explores the implications of Al-Ghazali’s criticism of their views. While doing so, this article also delves into the fundamental idea of the nature of prophecy, and transcendental attributes associated with it.
Organism, Self, Umwelt: A New Approach to Organismic Individuality
Creators: name: Koutroufinis, Spyridon A.
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Organisms exhibit a specific form of biological individuality. In contemporary biosciences, explanations of organismic dynamics are often reduced to mechanistic descriptions. It is taken for granted that complex biological processes of different kinds are reducible to molecular and other “mechanisms”. In this paper, I show (1) that organisms express a form of individuality that is realized by a particular kind of causality and (2) that organismic causality transcends the logic of mechanisms used in contemporary biosciences. Based on new insights about organismic dynamics as well as Jakob von Uexküll’s concept of “Umwelt” (meaningful environment), I analyze organismic causality and show that the latter constitutes a form of selfhood alien to both inorganic nature and mechanisms.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Kantian monads in a Platonic world. Some remarks on the philosophical background of Jakob von Uexküll’s Umweltlehre
Creators: name: Brentari, Carlo
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: This paper aims at investigating some philosophical assumptions of Jakob von Uexküll’s biological Umweltlehre. After a short exposition of Uexküll’s (Kantian) idea of the animal subjectivity, the contribution will focus on the correction strategies Uexküll puts into act, in different places of his works, to remedy the main limit of his subjectivism (i.e., the risk of solipsism). We will examine, in particular, three of these strategies, showing that they resume (explicitly or implicitly) some classical patterns of thought of Western philosophy: 1) Aristotelian (neo)vitalistic notions; 2) “Leibnizian” forms of pre-established harmony; 3) Platonic idealism. In the concluding remarks, the paper will highlight some limits of the philosophical toolkit through which Uexküll faces the problems arising from his ‘modified Kantism’. This criticism opens up the possibility to assign the role of coordinating and harmonizing the different species-specific Umwelten to evolution by natural selection (in the way some current evolutionists think of it).
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Body enactivism and primordial affectivity. Max Scheler and Jacob von Uexküll’s aporia
Creators: name: Cusinato, Guido
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: This paper is aimed to discuss and reconsider life categories starting from German phenomenologist Max Scheler’s analysis of the “lived body” (Leib), which he developed between 1909 and 1928 independently of Husserl. For the philosophy of biology, Scheler’s phenomenology of corporeality is of outstanding importance, because the categories it applies to the Leib are not taken from the inorganic world, as is ultimately still the case with Husserl, but from Jacob von Uexküll’s biology and Bergson’s philosophy. It therefore represents one of the most significant attempts to rethink life in accordance with the categories proper to life itself. Scheler’s reception of Uexküll’s works was not straightforward. At first, Scheler read Uexküll against Kant and interpreted the theory of Bauplan in the sense of a merely selective activity (1909-1916). Subsequently, he used the notion of Bauplan to develop his own concept of body schema (Leibschema) as the enactive center of perception. At this point, Scheler was compelled to tackle the fundamental aporia at the center of Uexküll’s system: How do different species communicate with each other if they belong to different environments (Umwelten)? In order to find a way out of Uexküll’s aporia, Scheler posited a basic unity of life on the unipathic level (Einsfühlung). Scheler’s solution was thus the following: Living beings in different environments (Umwelten) communicate with each other because every living organism is endowed with an elementary «grammar of expression», which on the level of primordial affectivity enables a pre-representative communication of all living forms, including plants. The most significant aspect of this solution is that Scheler could develop an enactive perspective of the organism without falling into Uexküll’s aporias of Kantian subjectivism, which are still found in several forms of contemporary enactivism.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Form, function and value in the emerging and self-organizing processes of the natural evolution
Creators: name: Di Bernardo, Mirko
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Keeping S.A. Kauffman’s agency theory and W.J. Freeman’s neurobiology of meaning as a projection period, the contribution through the use of a specific epistemological approach linked to the theory of biological complexity examines the opportunity of interpreting life and cognition as emerging phenomena such as hierarchical levels of self-organization in continuous co-evolution. At this level the relationship between form, function and value becomes a generative biological information of always new dialectical processes of organizational closure. From this point of view, the hypothesis to investigate is that rudiments of semantics, intentionality and value arise with autonomous agents and therefore are intrinsically related to the notion of life itself.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Mixing-demixing transition and void formation in quasi-2D binary mixtures on a sphere
Creators: name: Truzzolillo, Domenico
Publisher: name: arXiv
Year: 2021
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Motivated by observations of heterogeneous domain structure on the surface of cells and vesicles and by domain formation due to the adsorption of complex molecules onto composite membranes, we consider a minimal quasi 2D-model to describe the structure of binary mixtures on the surface of a spherical particle. We study the effect of miscibility and adsorbing particle (AP) addition on the mixture structure. We define a new scalar quantity, the geodesic mixing parameter $Ξ$, through which we detail the effect of miscibility and the role of preferential affinity of APs with one of the two components of the mixture, distinguishing unambiguously between mixing and demixing solely induced by APs. Finally, by inspecting the distributions of void sizes, we show how void formation is ruled by miscibility and AP-mixture interactions, which control the transition from exponentially-tailed to fat-tailed distributions.
description: 13 pages, 15 figures, 2 tables. The following article has been accepted by The Journal of Chemical Physics. After it is published, it will be found at https://aip.scitation.org/journal/jcp
Towards Real-time Classification of Astronomical Transients
Creators: name: Mahabal, A.
name: Djorgovski, S. G.
name: Williams, R.
name: Drake, A.
name: Donalek, C.
name: Graham, M.
name: Moghaddam, B.
name: Turmon, M.
name: Jewell, J.
name: Khosla, A.
name: Hensley, B.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Exploration of time domain is now a vibrant area of research in astronomy, driven by the advent of digital synoptic sky surveys. While panoramic surveys can detect variable or transient events, typically some follow-up observations are needed; for short-lived phenomena, a rapid response is essential. Ability to automatically classify and prioritize transient events for follow-up studies becomes critical as the data rates increase. We have been developing such methods using the data streams from the Palomar-Quest survey, the Catalina Sky Survey and others, using the VOEventNet framework. The goal is to automatically classify transient events, using the new measurements, combined with archival data (previous and multi-wavelength measurements), and contextual information (e.g., Galactic or ecliptic latitude, presence of a possible host galaxy nearby, etc.); and to iterate them dynamically as the follow-up data come in (e.g., light curves or colors). We have been investigating Bayesian methodologies for classification, as well as discriminated follow-up to optimize the use of available resources, including Naive Bayesian approach, and the non-parametric Gaussian process regression. We will also be deploying variants of the traditional machine learning techniques such as Neural Nets and Support Vector Machines on datasets of reliably classified transients as they build up.
description: 7 pages, 3 figures, to appear in proceedings of the Class2008 conference (Classification and Discovery in Large Astronomical Surveys, Ringberg Castle, 14-17 October 2008)
Modeling and Simulation of Scalable Cloud Computing Environments and the CloudSim Toolkit: Challenges and Opportunities
Creators: name: Buyya, Rajkumar
name: Ranjan, Rajiv
name: Calheiros, Rodrigo N.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences
subject: C.2.4

description: Cloud computing aims to power the next generation data centers and enables application service providers to lease data center capabilities for deploying applications depending on user QoS (Quality of Service) requirements. Cloud applications have different composition, configuration, and deployment requirements. Quantifying the performance of resource allocation policies and application scheduling algorithms at finer details in Cloud computing environments for different application and service models under varying load, energy performance (power consumption, heat dissipation), and system size is a challenging problem to tackle. To simplify this process, in this paper we propose CloudSim: an extensible simulation toolkit that enables modelling and simulation of Cloud computing environments. The CloudSim toolkit supports modelling and creation of one or more virtual machines (VMs) on a simulated node of a Data Center, jobs, and their mapping to suitable VMs. It also allows simulation of multiple Data Centers to enable a study on federation and associated policies for migration of VMs for reliability and automatic scaling of applications.
description: 11 pages, 11 figures
Identity, freedom, emergence. A reflection on the meaning of action
Creators: name: Zhok, Andrea
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Freedom and the meaningfulness of action are not just natural allies, as one might expect. They can be also incompatible instances, since radical absolute freedom threatens any action with emptiness and groundlessness. In the present pages we try to tackle this ‘paradox of freedom’, where actions deprived of all freedom, and actions radically free, appear both to be threatened by meaninglessness. We do so by outlining a comprehensive conception of agents’ freedom as possibilization, which reveals itself in the forms of biological, cultural and personal history, and which is capable of neutralizing the aporetic character of the ‘paradox of freedom’.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
NOMA Empowered Integrated Sensing and Communication
Creators: name: Wang, Zhaolin
name: Liu, Yuanwei
name: Mu, Xidong
name: Ding, Zhiguo
name: Dobre, Octavia A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: A non-orthogonal multiple access (NOMA) empowered integrated sensing and communication (ISAC) framework is investigated. A dual-functional base station serves multiple communication users employing NOMA, while the superimposed NOMA communication signal is simultaneously exploited for target sensing. A beamforming design problem is formulated to maximize the weighted sum of the communication throughput and the effective sensing power. To solve this problem, an efficient double-layer penalty-based algorithm is proposed by invoking successive convex approximation. Numerical results show that the proposed NOMA-ISAC outperforms the conventional ISAC in the underloaded regime experiencing highly correlated channels and in the overloaded regime.
description: 14 pages, 7 figures, accepted for the publication in IEEE Communications Letters
Meta-Identität / Unstable identities: towards a plastic morphology
Creators: name: Tedesco, Salvatore
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: The essay aims to investigate some developments in W.G. Sebald’s poetics, explaining the foundations of a morphology starting from the relationship with the theories of Viktor von Weizsäcker and Rudolf Bilz. The anthropological model elaborated by Rudolf Bilz, between the study of the origin of mythologemes and the investigation of unstable identities, allows us to investigate the presence in Sebald’s work of some decisive authors of modernity. In this way the proposal of a plastic morphology is outlined in its relationships with an unstable and multiple concept of identity, and in the very original resumption by Sebald of some mythological themes that finds expression in it.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Beyond the eidetics of living beings: contingency, plasticity, individuality
Creators: name: Lupo, Rosa Maria
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Saving living phenomena means saving their contingency, their plasticity, their individuality. A fruitful dialogue between metaphysics, phenomenology and morphology can be of help to investigate the ontological question of form, giving us the possibility to investigate the question of form and its epistemological significance providing a revision of that eidetic approach which instead is in danger of losing the sense of the continuous plastic morphogenesis of living beings.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Geniale Übersetzungen. Goethe – Benjamin – Spengler
Creators: name: Ophälders, Markus
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Morphology and metamorphosis are analyzed as ways of genial translations. In the case of Goethe as a translation of natural rules into artistical rules (Faust), in that of Spengler and Benjamin as that of natural morphology into proceedings of philosophy of history. Metamorphosis and translation are ways of mediation between different fields of scientific and cultural activities. Moreover, they represent a mimetic and intuitive way of dealing with problems which does not transcend into mere logical thought. This part is treated also in reference to Aristotle and Hegel. At the end the approaches of Benjamin and Spengler are briefly criticized and compared in reference to their Goethean origin and to the difference between their outcome and solutions.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Beyond the arché. Aristotle, Goethe, Heidegger, Schürmann
Creators: name: Porceddu Cilione, Pier Alberto
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: The aim of this article is to rethink the indispensable connection between aesthetics and life sciences. According to a consolidated tradition, the fundamental point of intersection between the two disciplines is represented by the concept of form. It is therefore to morphology that the task of thinking about the nature of form and the form of nature is ascribed. In this sense, Goethe and the debates on morphology arising from his texts represent an essential speculative starting point. However, the Goetheian teaching is, in this context, even more compelling, because morphology is already configured as a science of form that suspends the kinetic difference between natural and artificial beings, between nature and art/technique. If nature, physis, has still been thought of by Aristotle as the realm of arché, it will be a question of comprehend how, through the testimony of Heidegger and Schürmann, it is possible to metaphysically found morphology by understanding the essential “anarchic” character of nature.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
“history” of biodiversity. A Bergsonian look at the theory of evolution
Creators: name: Tahar, Mathilde
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Neo-Darwinism, through the combination of natural selection and genetics, has made possible an explanation of adaptive phenomena that claims to be devoid of metaphysical presuppositions. What Bergson already deplored and what we explore in this paper is the implicit finalism of such evolutionary explanations, which turn living beings into closed and static systems rather than understanding biological evolution as a process characterized by its interactions and temporal openness. Without denying the heuristic efficiency of the explanation resting upon natural selection, we analyze what it leaves out and what remains to be explored: the unpredictability of the evolutionary process. We will therefore study the role of contingency in evolution, as Stephen J. Gould proposed, but we will also consider the causality specific to the living world that makes it impossible to reduce it to a simple algorithm, as proposed by Daniel Dennett among others, but that it is really a creative causation, or dialectical spiral.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
living difference. Morphological issues in Ruyer, Simondon and Deleuze
Creators: name: Tenti, Gregorio
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Philosophical morphology carries on a difficult tradition, bound with different currents and periods of thought. During the 20th century, an original and profound reflection on the living form can be recognized in the so-called French biophilosophy. Morphology, thus, seems to re-emerge under the guise of a post-critical ontology of becoming. Thinkers like Raymond Ruyer, Gilbert Simondon and Gilles Deleuze showed that they were deeply aware of the manifold issues revolving around the notion of form and of their interconnections, and were able to provide original solutions to these problems in the framework of their thought systems. More recently, these reflections have asserted themselves in virtue of their coherence and their speculative force. This paper aims at a theoretical overview of the morphological spirit of biophilosophy that retraces the complex exchanges of influences between these three significant thinkers, Ruyer, Simondon and Deleuze. Along the focal nodes of temporality, spatiality and individuality, a renewed image of philosophical morphology will result from the vitality of their theoretical proposals.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Logic Shrinkage: Learned FPGA Netlist Sparsity for Efficient Neural Network Inference
Creators: name: Wang, Erwei
name: Davis, James J.
name: Stavrou, Georgios-Ilias
name: Cheung, Peter Y. K.
name: Constantinides, George A.
name: Abdelfattah, Mohamed S.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Hardware Architecture (cs.AR)
subject: FOS: Computer and information sciences

description: FPGA-specific DNN architectures using the native LUTs as independently trainable inference operators have been shown to achieve favorable area-accuracy and energy-accuracy tradeoffs. The first work in this area, LUTNet, exhibited state-of-the-art performance for standard DNN benchmarks. In this paper, we propose the learned optimization of such LUT-based topologies, resulting in higher-efficiency designs than via the direct use of off-the-shelf, hand-designed networks. Existing implementations of this class of architecture require the manual specification of the number of inputs per LUT, K. Choosing appropriate K a priori is challenging, and doing so at even high granularity, e.g. per layer, is a time-consuming and error-prone process that leaves FPGAs' spatial flexibility underexploited. Furthermore, prior works see LUT inputs connected randomly, which does not guarantee a good choice of network topology. To address these issues, we propose logic shrinkage, a fine-grained netlist pruning methodology enabling K to be automatically learned for every LUT in a neural network targeted for FPGA inference. By removing LUT inputs determined to be of low importance, our method increases the efficiency of the resultant accelerators. Our GPU-friendly solution to LUT input removal is capable of processing large topologies during their training with negligible slowdown. With logic shrinkage, we better the area and energy efficiency of the best-performing LUTNet implementation of the CNV network classifying CIFAR-10 by 1.54x and 1.31x, respectively, while matching its accuracy. This implementation also reaches 2.71x the area efficiency of an equally accurate, heavily pruned BNN. On ImageNet with the Bi-Real Net architecture, employment of logic shrinkage results in a post-synthesis area reduction of 2.67x vs LUTNet, allowing for implementation that was previously impossible on today's largest FPGAs.
description: Accepted manuscript uploaded 04/12/21. DOA 22/11/21
title: AGIRE L’ACCOGLIENZA. Percorso di ricerca sul lavoro sociale all’interno del Sistema di accoglienza e integrazione (SAI)
Creators: name: Giovannetti, Monia
name: Accorinti, Marco
Publisher: name: Roma TrE-Press
Year: 2023

description: L’operatore dei servizi per l’accoglienza di richiedenti asilo e rifugiati rappresenta ancora oggi nel panorama professionale italiano una figura connotata da un elevato grado di complessità e varietà di competenze. Tale eterogeneità emerge anche nella ricerca sociale che è alla base della presente pubblicazione e che propone, per la prima volta, a venti anni dalla costituzione del Sistema di Accoglienza e Integrazione (denominato prima SPRAR poi SIPROIMI e ora SAI), un approfondimento sul complesso mondo del lavoro sociale impegnato nell’accoglienza e nell’inserimento sociale, abitativo, educativo, formativo, professionale dei richiedenti e titolari di protezione internazionale. Il testo contiene anche un contributo originale di riflessione sulle caratteristiche dell’amministrazione condivisa nel lavoro sociale, redatto da Luciano Gallo e Luca Pacini. È inoltre allegata una analisi storico-organizzativa dell’evoluzione del sistema di accoglienza per richiedenti asilo e rifugiati in Italia.
Fantastic morphologies: animal form between mythology and Evo-Devo
Creators: name: Maggiore, Valeria
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: Since ancient times, man has shown a genuine passion for the recombination of visual elements in unusual and extraordinary forms; but, if the ancients admitted the existence of mythological creatures, today we are fully aware that their existence is limited to the ontological domain of the “merely thinkable” because imaginary beings are irreconcilable with physical and biological laws. In this article I try to elucidate what differentiates from a morphological point of view the imaginary beings described by the pens of poets (such as Sphinx, mermaids and centaurs) from bizarre but existing animals (i.e. the small South American Axolotl, the Yeti Crab, etc.) or from some specimens belonging to common animal species, but which present strange morphologies due to genetic errors. In dialogue with some positions of contemporary biology and literary criticism, I tried to investigate the rules of form to understand how historical and architectural constraints can influence the morphology of the living and why these existing creatures generate in us at the same time a feeling of wonder and dismay.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Living forms in becoming between old constraints and unexpected opportunities of change
Creators: name: Minelli, Alessandro
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: What does it mean to understand a biological form? Traditional approaches have tried to generate families of form through generative algorithms, often mathematically elegant (e.g., fractals) but very far from biological reality, or to explain it in terms of adaptation. In recent times, a different reading of living forms has been fueled by progress in developmental biology. The key point is that natural selection can only act on the products of the development mechanisms actually operating in nature. There are biological forms that, had they appeared, would have been successful, but simply never saw the light. There are also reciprocal examples of ‘monstrous’ individuals whose chances of survival are uncertain and are not able to reproduce, yet they often reach adulthood, demonstrating that existing developmental mechanisms are capable of constructing forms other than normal ones. Thus, to understand living forms as these exist in nature we cannot be satisfied either with the functionalist logic of evolutionary biology, or with the explanations provided by developmental biology in terms of ontogenetic processes: separately taken, neither is sufficient to explain the biological forms we find in nature. However, we can attempt to integrate between the two approaches, following the recent program of evolutionary developmental biology (evo-devo). Within this discipline, an original program has taken shape, focusing on evolvability, modularity and the origin of evolutionary novelties. Evolutionary and developmental changes of living forms can be modular or systemic. Modularity allows different kinds of development reprogramming: heterometry, heterotopy, heterochrony, which involve, in the order, changes in temporal, positional and quantitative aspects of the production of individual body parts during development. Despite the explosive development of studies on the genetic control of developmental processes, a thorough knowledge of the genotype of an animal or plant is not sufficient to predict its structure. The expression of one gene is generally involved in many traits (pleiotropy), while identical or almost identical traits can be achieved even in the presence of differences in the genes or in the gene networks involved in their control (convergence or redundancy). Moreover, the phenotype that actually shows up depends also on influences from the environment in which the development takes place (phenotypic plasticity), and on often standing and specific interactions with other organisms, as in the fungus-alga symbiosis of lichens and the interactions of multicellulars – humans included – with their microbiome.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
THE ADHESION MOLECULE L1: A NOVEL PLAYER IN OVARIAN CANCER VASCULATURE
Creators: name: ANGIOLINI, FRANCESCA
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: Ovarian cancer represents an outstanding clinical challenge because of its high mortality rate, mainly due to tumor relapse and chemoresistance. The identification of novel targets and strategies for the treatment of OC is clearly an unmet need in clinical oncology. In this context, drugs that interfere with tumor neovascularization have shown promising results in recent clinical trials. However, the beneficial effect of anti-angiogenic therapies is often modest and transient: in OC patients, for example, it has been observed only a limited increase in progression-free survival. Thus, the definition of novel druggable targets within the tumor vasculature will have profound implications, particularly for those tumor types, such as OC, that respond poorly to conventional anti-cancer treatments. L1 is a transmembrane glycoprotein belonging to the immunoglobulin superfamily that was initially characterized as an adhesion molecule playing a key role in the development of nervous system. However, several studies have demonstrated its involvement in several types of human cancer, including ovarian carcinoma. In this context, L1 expression is generally associated with poor diagnosis, an aggressive behavior and advanced tumor stage. Moreover, L1 induces a motile and invasive phenotype, supporting metastatic spread, and promotes chemoresistance. Our laboratory has obtained compelling evidence that L1 is aberrantly expressed in tumor vasculature and exerts an unexpected, pleiotropic function in endothelial cells. Based on these findings and on the pivotal role of angiogenesis in ovarian cancer, in this work I have investigate the functional role of L1 within the OC-associated vasculature. My results revealed that L1 is particularly abundant in OC vasculature as compared to normal vessels. Moreover,, vascular L1 was found to be a causal player in OC progression, possibly due to an endothelial cell-autonomous effect on OC vascularization, concomitant to a positive regulation of ovarian cancer stem cell function. This research, besides giving insights into novel pathways involved in pathological angiogenesis, provides the rationale for exploring the clinical relevance of L1 expression and function in OC vessels and in their crosstalk with tumor cells, possibly opening new avenues for the development of innovative targeted therapies for OC malignancy.
Additional file 6 of Single-cell RNA sequencing reveals the mechanism of sonodynamic therapy combined with a RAS inhibitor in the setting of hepatocellular carcinoma
Creators: name: Wu, Bolin
name: Yuan, Yanchi
name: Liu, Jiayin
name: Shang, Haitao
name: Dong, Jing
name: Liang, Xitian
name: Wang, Dongxu
name: Chen, Yichi
name: Wang, Chunyue
name: Zhou, Yang
name: Jing, Hui
name: Cheng, Wen
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: Additional file 6: Table S1. Sequencing information.
title: Strategisches Management
Creators: name: Geißler-Piltz, Brigitte
name: Weiß, Kersti
name: Heimer, Thomas
name: Treperman, Jérôme
name: Schmitz, Stephan
name: Fröse, Marlies W.
name: Reiff, Gerda
name: Weiß, Malte
name: Ehmer, Susanne
name: Wind, Kathrin
name: Schmidt, Michael
name: Kaldenkerken, Carla van
name: Kunkel-van Kaldenkerken, Roland
name: Rothenberg, Günter
name: Fengler, Jörg
name: Birth, Gabriele
name: Kuchenbecker, Manuela
name: Nord, Ilona
Publisher: name: kassel university press
Year: 2012
Subjects: classificationCode: 300
subject: 300
classificationCode: 650
subject: 650
classificationCode: Strategisches Management
subject: Strategisches Management
classificationCode: Supervision
subject: Supervision
classificationCode: Coaching
subject: Coaching

description:
Was tun in für Unternehmen und Organisationen kritischen Zeiten? Den Kopf in den Sand stecken? Oder dem Prinzip „höher – schneller – weiter“ folgen? Oder besser innehalten,nachdenken und Entwicklungen planen?Aus verschiedenen Perspektiven – der Ökonomie, der Mediation, der Supervision, der Organisations- und Personalentwicklung, des Coachings sowie der von Führungskräften – werden hier alternative Ideen und SINN- und WERT-volle Strategien für produktive Entwicklungen beschrieben. Sie bieten Antworten u. a. auf die folgenden Fragen:
- Wie können Krisen, Konflikte und andere Veränderungen, die Organisationen und Menschen immer wieder erschüttern, verstanden und sinnvoll durchgestanden werden?
- Wie können interne und externe Beratungsprozesse koordiniert und in Supervision strategisch gedacht werden?
- Wie können gute Entwicklungen in einer wertorientierten großen Organisation gelingen?
Wissen, Liebe, Engagement, Zuversicht, Vertrauen – all dies sind Werte, die sich durch Teilen nicht verbrauchen, sondern potenzieren und so REICHTUM bilden; sie sind das Geheimnis erfolgreicher Strategien – für Personen wie für Organisationen. Kersti Weiß ist Diplom-Psychologin, Supervisorin (DGSv), psychologische Psychotherapeutin, Organisationsberaterin und Weiterbildnerin sowie Leiterin des Fachbereichs Supervision im Institut für Personalberatung, Organisationsentwicklung und Supervision (IPOS) in der Evangelischen Kirche Hessen und Nassau.
AN ACCURATE MASS MODEL OF THE GALAXY CLUSTER ABELL 2163 VIA STRONG GRAVITATIONAL LENSING
Creators: name: RESCIGNO, UMBERTO
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: The gravitational lensing effect is the phenomenon for which the electromagnetic radiation, departing from a luminous object is deflected in the proximity of a mass distribution (the gravitational lens), placed between the source and an observer. In the relativistic interpretation, massive objects curve the space-time continuum and light rays, which follow this curvature, are bent passing close to these deflectors. Thus, a gravitational lens essentially acts on light as a normal lens does in geometrical optics. Precise modeling of massive galaxy clusters acting as lenses is crucial: it would help to disentangle the discrepancies emerging between the predictions of the cosmological concordance model and the observations at the scale of collapsed structures. The gravitational lens which is the subject of the present thesis is Abell 2163, one of the most massive galaxy clusters known, at redshift 0.2. Abell 2163 is a challenging system and a goldmine for contemporary astrophysics: its complex structure shows a variety of interacting sub-systems manifesting their activity all over the electromagnetic spectrum. A missing key element to unveil the properties of this cluster is to map its mass distribution at high resolution. We perform such a reconstruction thanks to the presence, in its core, of the typical effects of the strong gravitational lensing regime, such as the presence of multiple images produced from single background sources. Using data from the Multi Unit Spectroscopic Explorer on the VLT, in Chile, we compile and release three astronomical catalogs, confirm known multiple images and discover new lensed galaxies. We then build, test and rank different mass models, using Hubble Space Telescope data and the positions of the observed multiple images as constraints. Finally, we provide the most precise strong lensing mass model of the Abell 2163 core: the model- predicted positions of the multiple images are, on average, only 2.5 pixels away from the observed ones. The precise results of the present thesis can improve a number of scientific programs and can contribute significantly to different lines of research, e.g., the definition of the Abell 2163 merging history and an initial test on a possible self-interaction of the dark matter.
Additional file 2 of Altered oxidant and antioxidant levels are associated with vascular stiffness and diabetic kidney disease in type 1 diabetes after exposure to acute and chronic hyperglycemia
Creators: name: Adeshara, Krishna
name: Di Marco, Elyse
name: Bordino, Marco
name: Gordin, Daniel
name: Bernardi, Luciano
name: Cooper, Mark E
name: Groop, Per-Henrik
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology

description: Supplementary Material 2
Spacetime Brout-Englert-Higgs effect in General Relativity interacting with p-brane matter
Creators: name: Bandos, Igor A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We review the manifestation of the Brout-Englert-Higgs effect in general relativity interacting with point-like and extended objects (p-branes including string for p=1 and membrane for p=2), which manifests itself in the appearance of the brane source in the Einstein equation while the graviton remains massless (hep-th/0112207, hep-th/0507197 and refs therein), and discuss briefly its relation and differences with the model for massive spin 2 field proposed recently by G. t'Hooft in [arXiv:0708.3184 [hep-th]].
description: LaTeX, jpconf class, 5 pages. Contribution to the Procs. of the ERE2009 Meeting, Bilbao, September 2009
Editors’ Introduction: Morphology, Organism, Evolution
Creators: name: Cusinato, Guido
name: Lupo, Rosa Maria
name: Minelli, Alessandro
name: Tedesco, Salvatore
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2021

description: In biology, interest in form was the prerogative of developmental biology, while it was practically neglected by evolutionary biology. This situation has changed a lot in recent decades and has led to a reinterpretation of the concept of evolution and evolutionism focusing more on the problem of form and morphology. In Italy, especially Alessandro Minelli, one of the editors of this issue, has dedicated his studies to the need to communicate form to structure, to reconnect morphology and evolution. This theme is a highly relevant one for philosophy, inasmuch as the question of form and morphology, since the days of Goethe and Bergson, has always been considered as the starting point for a philosophy of the living being endowed with its own categories that cannot be reduced to those of physics.
description: Thaumàzein | Rivista di Filosofia, V. 8 (2020): Morphology, Plasticity, and Transformation between Philosophy and Biology
Ultra high frequency radio echo sounding of glaciers
Creators: name: Narod, B. Barry
Publisher: name: University of British Columbia
Year: 2010

description: For determining the thickness of ice, radio echo sounding of glaciers is well established as a technique for rapid gathering of data. However it has become evident that radio echo sounder parameters must be tailored to meet specific requirements in order to achieve best results. In particular rapid sounding of temperate, alpine glaciers and larger polar valley glaciers could be surveyed by a radio echo sounder having a very short pulse, very wide land response and narrow beam antenna. Such requirements can be fulfilled by Ultra High Frequency (300 MHz - 3 GHz) radio echo sounders, improved performance being achieved at the expense of decreased maximum range. This thesis, after considering previous attempts at radio echo sounding of glaciers, with respect to surveying valley and temperate glaciers, proposes and details a UHF radio echo sounder operating at 840 MHz. Conventional performance is predicted, and some new experiments, possible because of the short wavelength, are proposed. Appended to the thesis is a review and discussion of problems associated with the use of thermistors as thermometers in snow or ice. A procedure is described for optimizing the techniques of thermistor selection and use.
Electroweak physics at the Tevatron
Creators: name: Nunnemann, Thomas
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Recent measurements of processes involving the electroweak bosons, Z and W, performed at the Fermilab Tevatron Collider are summarized. The large integrated luminosities collected by both the D0 and CDF Collaborations enable precise measurements of differential single boson production cross sections, the determination of the W mass with unprecedented precision, and the observation of diboson production including ZZ.
description: 6+1 pages, plenary talk at Physics at LHC 2008, Split, Croatia (for the D0 and CDF Collaborations)
MECHANISMS CONTROLLING THE INTEGRITY OF CONVERGING FORKS DURING REPLICATION TERMINATION
Creators: name: CHOUDHARY, RAMVEER
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: During S phase, natural fork pausing elements including replication termination zones (TERs) and transcribed genes, can easily lead to genotoxicity and chromosome fragility at fragile sites (CFs), known as hotspots for DNA breaks and chromosomal rearrangements, particularly in cancer cells. However, the key factors and pathways protecting the integrity of CFSs are not well understood. In order to elucidate these mechanisms, we used yeast as a model system, and combined genetic and genomic studies aimed at identifying fragile sites genome-wide. We found that centromeres, rDNA, telomeres and TERs represent hot spots for copy number variation (CNV) in wild-ype yeast cells exposed to replication stress. We found that top2 contributes to relieve the topological stress and extensive fork pausing during termination at TERs. We also observed that fragility at these sites is greatly enhanced in checkpoint mutants (Tel1-ATM1 and Mec1-ATR1), likely due to their inability to uncouple transcription from gene gating, thus leading to topological stress in front of replication forks. TER fragility in checkpoint defective cells can be partially rescued by Top2 and Condensin complex inactivation. We further demonstrated that Pif1 family helicase, Rrm3, regulate extensive fork pausing at TERs and endogenous pausing sites by suppressing RNA:DNA hybrid (R-loops) accumulation. Alongside, a RNA:DNA helicase Senataxin1 (Sen1) coordinates replication and transcription collision at TERs and endogenous fork pausing. Absence of Sen1 accumulates CNVs at TERs and double-strand DNA breaks. We show that programmed fork pausing and resolution of R-loops are key processes for TER integrity. Accordingly, sen1 rrm3 double mutants, accumulate gaps and RNA:DNA hybrids at TERs and fail to fuse replicons; moreover, these mutants exhibit unscheduled condensation events at TERs leading to chromosome entangling. Taken together, our data strongly suggests that, the replication checkpoint, Sen1 and Rrm3, coordinate replication termination to prevent accumulation of unsolved topological constrains and premature recruitment of Condensins and Top2.
Additional file 1 of Sleep and nighttime behavior disorders in older adults: associations with hypercholesterolemia and hypertriglyceridemia at baseline, and a predictive analysis of incident cases at 12 months follow-up
Creators: name: Hallab, Asma
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 1.
title: LLM-Supported Safety Annotation in High-Risk Environments
Creators: name: Eskandari, Mohammad
name: Indukuri, Murali
name: Lukin, Stephanie M.
name: Matuszek, Cynthia
Publisher: name: Open Review
Year: 2025
Subjects: subject: Human-Robot Interaction
subject: UMBC Interactive Robotics and Language Lab
subject: Safety Annotation
subject: Hazard Detection
subject: Virtual Reality
subject: Large Language Models

description: HRI 2025 Workshop VAM Submission
description: This paper explores how large language model-based robots assist in detecting anomalies in high-risk environments and how users perceive their usability and reliability in a safe virtual environment. We present a system where a robot using a state-of-the-art vision-language model autonomously annotates potential hazards in a virtual world. The system provides users with contextual safety information via a VR interface. We conducted a user study to evaluate the system's performance across metrics such as trust, user satisfaction, and efficiency. Results demonstrated high user satisfaction and clear hazard communication, while trust remained moderate.