cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Timor's fauna influence of scale, history and land-use on faunal patterning
Creators: name: Trainor, Colin
Publisher: name: Charles Darwin University
Year: 2010

description: This study has focussed on the impact of forest disturbance and forest type on community patterns in the bird, mammal, reptile and ant faunas of Timor-Leste, with particular focus on the Lautem district of the far east of the island, and on patterns in the distributional ecology of birds. Island area was the overwhelming factor underlying bird species richness in a biogeographic analysis of 51 Lesser Sunda islands, highlighting the importance of habitat area; but the avifauna had ‘relaxed’ since Pleistocene-era sea levels. Bird species similarity decayed monotonically (particularly for specialised forest birds, endemics, globally threatened and pigeons) with distance indicating the importance of isolation. The responses of bird groups and individual bird species to habitat type and forest cover was examined for West and East Timor, and for the well-forested Lautem district in East Timor. The abundance of forest birds, pigeons and frugivorous birds was 20-45% greater in East Timor compared to the West; forest cover was also twice as extensive in the East. There was a high similarity of bird species composition of ‘wooded’ habitats in the Lautem district analysis. Bird abundance increased where forest cover within 3 km was more extensive; for threatened and also restricted-range birds, abundance doubled when forest extent was >10 km2. The savanna woodland community was dominated by forest specialists and was most similar to the dry forest avifauna, but forest birds were shown to be only abundant in savanna when extensive primary tropical forest is available nearby. The ant fauna was species poor and dominated mostly by South East Asian forest ants with a small proportion of Australian taxa including several Iridomyrmex species previously considered as Australian endemics. The land mammal and reptile fauna has been greatly impacted by recent introductions. Further support for land mammal decline is documented, and native geckos may also have undergone decline.
Rock outcrops as potential biodiversity refugia under climate change in North Patagonia
Creators: name: Speziale, Karina L.
name: Ezcurra, Cecilia
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Evolutionary Biology

description: Background: Under climate-change scenarios, rock outcrops, by providing microclimatically diverse habitats, different from those of surrounding zonal vegetation matrix, may serve as climatic refugia and thereby facilitate the persistence of specialist species.Aim: We tested whether rock outcrops of southern temperate latitudes could act as local refugia for a cold-adapted flora in the face of global warming.Methods: We related species composition of 50 outcrops and that of their surrounding vegetation to climatic data at local and regional scales to establish whether species distributions reflected differences that could indicate the existence of climatic refugia.Results: While at a regional scale, species composition of the outcrops across the study area was related to mean annual precipitation and mean annual maximum temperature, locally, southern faces of outcrops had different species and lower maximum temperatures than insolated north faces and surrounding vegetation plots.Conclusions: South faces of outcrops by providing cool microhabitats, and currently harbouring species not found in the surrounding zonal vegetation matrix, could serve as local refugia for heat-intolerant plants and other microthermic organism. The degree of ‘stability’ of these refugia will depend on the degree of future change in climate. Therefore, it is important to plan protected area networks that maximise local environmental heterogeneity, including the protection of rock outcrops both as refugia for cold-adapted species and as potential stepping stones that would allow dispersal of these species between supportive environments through unfavourable ones.
A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos
Creators: name: Yu, B.
name: Morrison, A.C.
name: Boerwinkle, E.
name: Grove, M.L.
name: Qi, Q.
name: Chen, H.
name: Jia, P.
name: Feofanova, E.V.
name: North, K.E.
name: Dai, Y.
name: Laurie, C.C.
name: Kaplan, R.C.
name: Cai, J.
name: Daviglus, M.
Publisher: name: Cell Press
Year: 2020

description: Variation in levels of the human metabolome reflect changes in homeostasis, providing a window into health and disease. The genetic impact on circulating metabolites in Hispanics, a population with high cardiometabolic disease burden, is largely unknown. We conducted genome-wide association analyses on 640 circulating metabolites in 3,926 Hispanic Community Health Study/Study of Latinos participants. The estimated heritability for 640 metabolites ranged between 0%–54% with a median at 2.5%. We discovered 46 variant-metabolite pairs (p value < 1.2 × 10−10, minor allele frequency ≥ 1%, proportion of variance explained [PEV] mean = 3.4%, PEVrange = 1%–22%) with generalized effects in two population-based studies and confirmed 301 known locus-metabolite associations. Half of the identified variants with generalized effect were located in genes, including five nonsynonymous variants. We identified co-localization with the expression quantitative trait loci at 105 discovered and 151 known loci-metabolites sets. rs5855544, upstream of SLC51A, was associated with higher levels of three steroid sulfates and co-localized with expression levels of SLC51A in several tissues. Mendelian randomization (MR) analysis identified several metabolites associated with coronary heart disease (CHD) and type 2 diabetes. For example, two variants located in or near CYP4F2 (rs2108622 and rs79400241, respectively), involved in vitamin E metabolism, were associated with the levels of octadecanedioate and vitamin E metabolites (gamma-CEHC and gamma-CEHC glucuronide); MR analysis showed that genetically high levels of these metabolites were associated with lower odds of CHD. Our findings document the genetic architecture of circulating metabolites in an underrepresented Hispanic/Latino community, shedding light on disease etiology.
Factores de riesgo para macrosomía fetal. Hospital Gineco Obstétrico Isidro Ayora (HGOIA), Quito.
Creators: name: Vasco-Morales, Santiago
name: Arturo-Delgado, Linda
name: Toapanta-Pinta, Paola
Publisher: name: Zenodo
Year: 2018
Subjects: Macrosomía Fetal, Factores de Riesgo

description: El recién nacido macrosómico es aquel que pesa 4000 gr o más, esta condición aumenta la morbilidad y mortalidad materno-fetal, además de aumentar el riesgo de sobrepeso, obesidad, y enfermedades crónicas no trasmisibles. Se realizó un estudio observacional retrospectivo, analítico caso control, de la base de datos del Sistema Informático Perinatal (SIP) del hospital Gineco Obstétrico Isidro Ayora de los últimos 8 años, los datos se analizaron mediante modelos de regresión logística simple y múltiple, se incluye el valor OR y su intervalo de confianza 95%, los datos se procesaron con el programa R 3.3.1 (2016). Las variables asociadas a macrosomía fueron: diabetes, edad gestacional, edad materna, gestas previas, estado civil y sexo del recién nacido. Además se encontró mayor porcentaje de nacimientos vía cesárea, y asociacion negativa con embarazo múltiple. La mayoría de los factores que se reportan asociación con macrosomía en las diferentes publicaciones, se encontró en este estudio.
Associations of maternal arsenic exposure with adult fasting glucose and insulin resistance in the Strong Heart Study and Strong Heart Family Study
Creators: name: Domingo-Relloso, A.
name: Howard, B.V.
name: Cole, S.A.
name: Tinkelman, N.E.
name: Tellez-Plaza, M.
name: Umans, J.G.
name: North, K.E.
name: Spratlen, M.J.
name: Factor-Litvak, P.
name: Francesconi, K.A.
name: MacCluer, J.
name: Grau-Perez, M.
name: Navas-Acien, A.
name: Goessler, W.
Publisher: name: Elsevier Ltd
Year: 2020

description: Experimental and prospective epidemiologic evidence suggest that arsenic exposure has diabetogenic effects. However, little is known about how family exposure to arsenic may affect risk for type 2 diabetes (T2D)-related outcomes in adulthood. We evaluated the association of both maternal and offspring arsenic exposure with fasting glucose and incident T2D in 466 participants of the Strong Heart Family Study. Total arsenic (ΣAs) exposure was calculated as the sum of inorganic arsenic (iAs) and methylated (MMA, DMA) arsenic species in maternal and offspring baseline urine. Median maternal ΣAs at baseline (1989–91) was 7.6 µg/g creatinine, while median offspring ΣAs at baseline (2001–03) was 4.5 µg/g creatinine. Median offspring glucose in 2006–2009 was 94 mg/dL, and 79 participants developed T2D. The fully adjusted mean difference (95% CI) for offspring glucose was 4.40 (−3.46, 12.26) mg/dL per IQR increase in maternal ΣAs vs. 2.72 (−4.91 to 10.34) mg/dL per IQR increase in offspring ΣAs. The fully adjusted odds ratio (95%CI) of incident T2D was 1.35 (1.07, 1.69) for an IQR increase in maternal ΣAs and 1.15 (0.92, 1.43) for offspring ΣAs. The association of maternal ΣAs with T2D outcomes were attenuated with adjustment for offspring adiposity markers. Familial exposure to arsenic, as measured in mothers 15–20 years before offspring follow-up, is associated with increased odds of offspring T2D. More research is needed to confirm findings and better understand the importance of family exposure to arsenic in adult-onset diabetes.
Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems
Creators: name: Fornage, M.
name: Hou, L.
name: Baccarelli, A.
name: Li, Y.
name: Melton, P.E.
name: Justice, A.E.
name: Demerath, E.
name: Lim, E.
name: Whitsel, E.A.
name: Conneely, K.
name: Heard-Costa, N.
name: Grove, M.L.
name: Mori, T.A.
name: Beilin, L.J.
name: Cupples, L.A.
name: Levy, D.
name: Stewart, J.D.
name: Liu, C.-T.
name: Fernandez-Rhodes, L.
name: Huang, R.-C.
name: Guan, W.
name: Bressler, J.
name: Boerwinkle, E.
name: Howard, A.G.
name: Gordon-Larsen, P.
name: North, K.E.
name: Gondalia, R.
name: Chittoor, G.
Publisher: name: Future Medicine Ltd.
Year: 2020

description: Aim: We conducted a methylome-wide association study to examine associations between DNA methylation in whole blood and central adiposity and body fat distribution, measured as waist circumference, waist-to-hip ratio and waist-to-height ratio adjusted for body mass index, in 2684 African-American adults in the Atherosclerosis Risk in Communities study. Materials & methods: We validated significantly associated cytosine-phosphate-guanine methylation sites (CpGs) among adults using the Women's Health Initiative and Framingham Heart Study participants (combined n = 5743) and generalized associations in adolescents from The Raine Study (n = 820). Results & conclusion: We identified 11 CpGs that were robustly associated with one or more central adiposity trait in adults and two in adolescents, including CpG site associations near TXNIP, ADCY7, SREBF1 and RAP1GAP2 that had not previously been associated with obesity-related traits.
title: Magnetic NiFe₂O₄ Nanoparticles Prepared via Non-Aqueous Microwave-Assisted Synthesis for Application in Electrocatalytic Water Oxidation
Creators: name: Simon, Christopher
name: Zakaria, Mohamed Barakat
name: Kurz, Hannah
name: Tetzlaff, David
name: Blößer, André
name: Weiß, Morten
name: Timm, Jana
name: Weber, Birgit
name: Apfel, Ulf-Peter
name: Marschall, Roland
Publisher: name: University of Bayreuth
Year: 2021
Subjects: subject: degree of inversion
subject: microwave synthesis
subject: nanoparticles
subject: oxygen evolution reaction
subject: spinelferrites
subject: 540

description: Phase-pure spinel-type magnetic nickel ferrite (NiFe₂O₄) nanocrystals in the size range of 4 to 11 nm were successfully synthesized by a fast and energy-saving microwave-assisted approach. Size and accessible surface areas can be tuned precisely by the reaction parameters. Our results highlight the correlation between size, degree of inversion, and magnetic characteristics of NiFe₂O₄ nanoparticles, which enables fine-tuning of these parameters for a particular application without changing the elemental composition. Moreover, the application potential of the synthesized powders for the electrocatalytic oxygen evolution reaction in alkaline media was demonstrated, showing that a low degree of inversion is beneficial for the overall performance. The most active sample reaches an overpotential of 380 mV for water oxidation at 10 mA cm−2 and 38.8 mA cm−2 at 1.7 V vs. RHE, combined with a low Tafel slope of 63 mV dec−1.
Covering Kiruna: a natural experiment in Arctic awareness
Creators: name: Steinberg, Philip E.
name: Bruun, Johanne M.
name: Medby, Ingrid A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Science Policy
Developmental Biology
Biological Sciences

description: At a time when the Arctic is attracting increasing international attention and a variety of actors are positioning themselves in anticipation of future developments, news reporters across the world face the challenge of explaining why the Arctic is relevant to the lives and realities of audiences, some of whom are far from the region itself. This challenge was felt particularly profoundly in May 2013, when events and controversies surrounding the Kiruna Arctic Council meeting tasked journalists around the world with explaining to their audiences what it means to have a legitimate interest in the Arctic and why the Arctic matters on a global scale. Media coverage from the eight Arctic Council member states, six candidate states, and six existing permanent observer states thus presented a natural experiment in Arctic awareness. In this article, an analysis of 280 news stories reporting on the Kiruna meeting is used to reveal how the media frame the Arctic as a region of increasing global significance – a region in which present-day participation is a strategic positioning for the future, and in which political presence holds symbolic significance for geopolitical relations far beyond the region's latitudinal borders.
Genetically Determined Height and Risk of Non-hodgkin Lymphoma
Creators: name: Wong Doo, N.
name: Brennan, P.
name: Berndt, S.I.
name: Machiela, M.J.
name: Ferri, G.M.
name: Monnereau, A.
name: Cerhan, J.R.
name: Jackson, R.D.
name: Cox, D.G.
name: Stewart, C.
name: Camp, N.J.
name: Conde, L.
name: Moore, A.
name: North, K.E.
name: Clavel, J.
name: Hjalgrim, H.
name: Piro, S.
name: Weinstein, S.
name: Patel, A.V.
name: Vijai, J.
name: Kane, E.
name: Link, B.K.
name: Teras, L.R.
name: McKay, J.
name: Wang, Z.
name: Southey, M.C.
name: Boffetta, P.
name: Bisanzi, S.
name: Molina, T.J.
name: Vermeulen, R.C.H.
name: Panagiotou, O.A.
name: Glimelius, B.
name: Glenn, M.
name: Offit, K.
name: Bracci, P.M.
name: Brooks-Wilson, A.R.
name: Chatterjee, N.
name: Cozen, W.
name: Weiderpass, E.
name: Liebow, M.
name: Albanes, D.
name: Canzian, F.
name: Chanock, S.J.
name: Vajdic, C.M.
name: Tinker, L.F.
name: Padoan, M.
name: Zheng, T.
name: Benavente, Y.
name: Severson, R.K.
name: de Sanjose, S.
name: Milne, R.L.
name: Ghesquières, H.
name: Riboli, E.
name: Giles, G.G.
name: Birmann, B.M.
name: Rothman, N.
name: Smedby, K.E.
name: Slager, S.L.
name: Spinelli, J.J.
name: Salles, G.
name: Staines, A.
name: Skibola, C.F.
name: Maynadie, M.
name: Zhang, Y.
name: Lan, Q.
name: Becker, N.
name: Nieters, A.
name: Adami, H.-O.
name: Habermann, T.M.
name: Ravichandran, V.
name: Travis, R.C.
name: Gapstur, S.M.
name: Foretova, L.
name: Miligi, L.
name: Arslan, A.A.
name: Curtin, K.
name: Melbye, M.
name: Morton, L.M.
name: Purdue, M.P.
Publisher: name: Frontiers Media S.A.
Year: 2020

description: Although the evidence is not consistent, epidemiologic studies have suggested that taller adult height may be associated with an increased risk of some non-Hodgkin lymphoma (NHL) subtypes. Height is largely determined by genetic factors, but how these genetic factors may contribute to NHL risk is unknown. We investigated the relationship between genetic determinants of height and NHL risk using data from eight genome-wide association studies (GWAS) comprising 10,629 NHL cases, including 3,857 diffuse large B-cell lymphoma (DLBCL), 2,847 follicular lymphoma (FL), 3,100 chronic lymphocytic leukemia (CLL), and 825 marginal zone lymphoma (MZL) cases, and 9,505 controls of European ancestry. We evaluated genetically predicted height by constructing polygenic risk scores using 833 height-associated SNPs. We used logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI) for association between genetically determined height and the risk of four NHL subtypes in each GWAS and then used fixed-effect meta-analysis to combine subtype results across studies. We found suggestive evidence between taller genetically determined height and increased CLL risk (OR = 1.08, 95% CI = 1.00–1.17, p = 0.049), which was slightly stronger among women (OR = 1.15, 95% CI: 1.01–1.31, p = 0.036). No significant associations were observed with DLBCL, FL, or MZL. Our findings suggest that there may be some shared genetic factors between CLL and height, but other endogenous or environmental factors may underlie reported epidemiologic height associations with other subtypes.
Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes
Creators: name: Yu, B.
name: Selvin, E.
name: Rebholz, C.M.
name: Mohney, R.P.
name: Mompeo, O.
name: Young, K.
name: Valdes, A.M.
name: Mangino, M.
name: Spector, T.D.
name: Menni, C.
name: North, K.E.
name: Bell, J.T.
name: Le Roy, C.I.
name: Zhu, J.
name: Boerwinkle, E.
Publisher: name: Taylor and Francis Inc.
Year: 2020

description: Type 2 diabetes (T2D) is associated with reduced gut microbiome diversity, although the cause is unclear. Metabolites generated by gut microbes also appear to be causative factors in T2D. We therefore searched for serum metabolites predictive of gut microbiome diversity in 1018 females from TwinsUK with concurrent metabolomic profiling and microbiome composition. We generated a Microbial Metabolites Diversity (MMD) score of six circulating metabolites that explained over 18% of the variance in microbiome alpha diversity. Moreover, the MMD score was associated with a significantly lower odds of prevalent (OR[95%CI] = 0.22[0.07;0.70], P = .01) and incident T2D (HR[95%CI] = 0.31[0.11,0.90], P = .03). We replicated our results in 1522 individuals from the ARIC study (prevalent T2D: OR[95%CI] = 0.79[0.64,0.96], P = .02, incident T2D: HR[95%CI] = 0.87[0.79,0.95], P = .003). The MMD score mediated 28%[15%,94%] of the total effect of gut microbiome on T2D after adjusting for confounders. Metabolites predicting higher microbiome diversity included 3-phenylpropionate(hydrocinnamate), indolepropionate, cinnamoylglycine and 5-alpha-pregnan-3beta,20 alpha-diol monosulfate(2) of which indolepropionate and phenylpropionate have already been linked to lower incidence of T2D. Metabolites correlating with lower microbial diversity included glutarate and imidazole propionate, of which the latter has been implicated in insulin resistance. Our results suggest that the effect of gut microbiome diversity on T2D is largely mediated by microbial metabolites, which might be modifiable by diet.
Epigenetic reprogramming in periodontal disease: Dynamic crosstalk with potential impact in oncogenesis
Creators: name: North, K.
name: Justice, A.
name: Tarran, R.
name: Fahimipour, F.
name: Scarel-Caminaga, R.M.
name: Barros, S.P.
name: Kim, S.
Publisher: name: Blackwell Munksgaard
Year: 2020

description: Periodontitis is a chronic multifactorial inﬂammatory disease associated with microbial dysbiosis and characterized by progressive destruction of the periodontal tissues. Such chronic infectious inflammatory disease is recognized as a major public health problem worldwide with measurable impact in systemic health. It has become evident that the periodontal disease phenotypes are not only determined by the microbiome effect, but the extent of the tissue response is also driven by the host genome and epigenome patterns responding to various environmental exposures. More recently there is mounting evidence indicating that epigenetic reprogramming in response to combined intrinsic and environmental exposures, might be particularly relevant due its plasticity and potential application towards precision health. The complex epigenetic crosstalk is reflected in the prognosis and progress of periodontal diseases and may also lead to a favorable landscape for cancer development. This review discusses epigenomics modifications focusing on the role of DNA methylation and pathways linking microbial infection and inflammatory pathways, which are also associated with carcinogenesis. There is a more clear vision whereas 'omics' technologies applied to unveil relevant epigenetic factors could play a significant role in the treatment of periodontal disease in a personalized mode, evidencing that public health approach should coexist with precision individualized treatment.
Plusiocampa (Dydimocampa) Paclt 1957
Creators: name: Sendra, Alberto
name: Antić, Dragan
name: Barranco, Pablo
name: Borko, Špela
name: Christian, Erhard
name: Delić, Teo
name: Fadrique, Floren
name: Faille, Arnaud
name: Galli, Loris
name: Gasparo, Fulvio
name: Georgiev, Dilian
name: Giachino, Pier Mauro
name: Kovac, L'ubomír
name: Lukić, Marko
name: Marcia, Paolo
name: Miculinić, Kazimir
name: Nicolosi, Giuseppe
name: Palero, Ferran
name: Paragamian, Kaloust
name: Pérez, Toni
name: Polak, Slavko
name: Prieto, Carlos E.
name: Turbanov, Ilya
name: Vailati, Dante
name: Reboleira, Ana Sofia P. S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Diplura
Campodeidae
Plusiocampa

description: Subgenus Dydimocampa Paclt, 1957
Dydimocampa Paclt, 1957: 46.
Diagnosis (Paclt 1957; Condé 1996)
Dydimocampa shares with Plusiocampa s. str. the same taxonomic features, with the exception of the two dorsal femoral macrosetae. This fact, together with their distribution patterns, suggests that
Dydimocampa is an artificial subgenus based on a single apomorphic feature that has probably appeared several times in Plusiocampa s. str.
Habitat and distribution
The three species treated here are cave-dwellers with a subterranean life-style and they are distributed in three disjunct karst areas in Europe (Fig. 211).
description: Published as part of Sendra, Alberto, Antić, Dragan, Barranco, Pablo, Borko, Špela, Christian, Erhard, Delić, Teo, Fadrique, Floren, Faille, Arnaud, Galli, Loris, Gasparo, Fulvio, Georgiev, Dilian, Giachino, Pier Mauro, Kovac, L'ubomír, Lukić, Marko, Marcia, Paolo, Miculinić, Kazimir, Nicolosi, Giuseppe, Palero, Ferran, Paragamian, Kaloust, Pérez, Toni, Polak, Slavko, Prieto, Carlos E., Turbanov, Ilya, Vailati, Dante & Reboleira, Ana Sofia P. S., 2020, Flourishing in subterranean ecosystems: Euro-Mediterranean Plusiocampinae and tachycampoids (Diplura, Campodeidae), pp. 1-138 in European Journal of Taxonomy 591 on pages 20-21, DOI: 10.5852/ejt.2020.591, http://zenodo.org/record/3659823
Habitat use and demographic characteristics of the endangered Carpentarian Rock-rat, Zyzomys palatalis
Creators: name: Trainor, Colin
Publisher: name: Charles Darwin University
Year: 1996

description: The Carpentarian Rock-rat Zyzomys palatalis is a critically endangered conilurine rodent known from four gorges on Wollogorang Station, in the south east Gulf region of the Northern Territory. The conilurine rodents include many 'old endemic' Australian rodents which have proven highly susceptible to population declines and extinction probably because their low reproductive rate does not allow sufficient population growth under elevated levels of predation (from introduced species) particularly in association with habitat loss or alteration (e.g. grazing and fires) (Smith and Quin 1996). In this thesis, the floristic and environmental relations of Gulf region gorge systems are characterised in detail in Chapter 2 to provide a framework for explaining the patterning of Z.palatalis. The environment of the gulf gorges, as characterised by plant composition and habitat attributes are not unique to this region. The plants are composed of two major groups, both of which are patchily widespread in rocky ranges throughout north western Australia. In the first group I include monsoon rainforest plants (sensu Liddle et al. 1994) and also mesic broadleaf woodland taxa, and the second group includes the sclerophyllous 'arid adapted' woodland taxa such as eucalypts and hummock grass. Although rainforest patches often appear to be discrete there is a floristic continuum from monsoon rainforests to broadleaf woodlands. Monsoon rainforests and broadleafwoodlands are fire-sensitive and are almost entirely restricted to rugged within-gorge habitats. Many of the plants occurring in these communities are widespread because they have similar origins (part of a Gondwanan flora) and / or because of dispersal by animal vectors (Liddle et al. 1994). Large fleshy or woody fruits and seeds were common reproductive structures in the rainforest and broadleafwoodland species and were identified as key food resources for Z.palatalis.
The developmental evaluation of a knowledge translation project in Indigenous primary health care quality improvement
Creators: name: Laycock, Alison Frances
Publisher: name: Charles Darwin University
Year: 2019

description: Continuous quality improvement (CQI) approaches used by healthcare services and teams to improve care systems and health outcomes have potential for informing wider system and policy improvement. The work presented in this thesis investigates this potential and provides knowledge for engaging stakeholders with aggregated CQI data, to inform multi-level system improvement. A developmental evaluation approach was applied to an online interactive dissemination process through which stakeholders interpreted reports of CQI data aggregated from 175 Indigenous primary health care (PHC) centres across five Australian jurisdictions. The study used mixed methods including document analysis, stakeholder surveys, participant interviews and facilitated processes with the research team. Data analysis guided adaptations to improve the dissemination process and the accessibility and use of its findings, and enhanced understanding about scaling participatory research. The integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework was applied retrospectively to analyse stakeholder engagement and implementation. The study found that system-based participatory research using CQI data, CQI-based methods and established networks could be applied at scale without intense facilitation efforts to support knowledge exchange and improvement. Stakeholders in diverse roles, organisations and settings collaboratively identified system-wide priority evidence-practice gaps, barriers and strategies for improvement across the scope of PHC. Stakeholders perceived the findings to be applicable at different system levels for planning, policy development, identifying research needs, supporting evidence-based care and strengthening capacity in data use. Commitment to best practice, perceived data quality and relevance, reporting formats, facilitation, competing work pressures and the organisational environment for change mediated use. Interactive dissemination is a promising strategy for system-based knowledge translation and for engaging multi-disciplinary stakeholders in participatory research. Further research should examine the resources required for effective engagement and data use in different contexts, explore facilitation in system-level interventions and investigate further potential of developmental evaluation for supporting implementation.
Adversarial Machine Learning in Prediction of Malware Families
Creators: name: Anonymous
Publisher: name: Zenodo
Year: 2025

description: Machine learning models play a critical role in modern cybersecurity, particularly in the classification of malware families. However, these models are vulnerable to adversarial manipulation, which can degrade their performance and reliability. This project investigates how data poisoning impacts machine learning-based malware classifiers. We use a dataset of API call sequences from malware samples to train a Random Forest model under clean and adversarial conditions. We then apply mitigation techniques, including adversarial training and feature importance filtering, to recover model robustness. Our results demonstrate significant degradation due to poisoning, with strong recovery after mitigation.
Detoxification of 4-chlorophenol in TiO2 sunlight system: effect of raw and treated solution on seed germination and plants growth of various sensitive vegetables
Creators: name: Elghniji, Kais
name: Salem, Sabrine
name: Mongi Ben Mosbah
name: Elimame Elaloui
name: Moussaoui, Younes
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences

description: The mineralization and detoxification of 4-chlorophenol (4-CP) were studied using a TiO2-paper/sunlight system. The possibility of reusing the photocatalyst was examined to determine the cost effectiveness of the method. Experiments were performed to establish optimum conditions for 4-CP removal. Phytotoxicity of photo-treated and raw 4-CP (100 mg L−1) solutions on seed germination and plant growth were carried out with the aim of water reuse and environment protection. The seeds irrigated with raw 4-CP solution showed lower sprout length while increase in sprout length was observed with the photo-treated solution for tomato (Lycopersicon esculentum), lettuce (Lactuca sativa), onion (Allium cepa), and turnip (Brassica rapa). Plant growth tests with the photo-treated 4-CP solution did not affect the leaf numbers compared to those irrigated with tap water. Photo-treated 4-CP solution can be used for irrigation in agriculture.
Physiography of the Sicilian region (1:250,000 scale)
Creators: name: Fantappiè, Maria
name: Priori, Simone
name: Costantini, Edoardo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Physiographic maps summarize and group the landforms of a territory into homogeneous areas in terms of kind and intensity of the main geomorphological process. These maps are often produced at semi-detailed scales, while examples at the regional scale are much less common. However, because the region is the main administrative level in Europe, physiographic maps can be very useful for land planning in many fields, such as ecological studies, risk maps, and soil mapping. This work presents a methodological example of a regional physiographic map, compiled at a 1:250,000 scale, representing the whole Sicilian region, the largest of the Mediterranean islands. The physiographic units were classified according to the geomorphological processes that were identified by stereo-interpretation of aerial photographs. In addition, information from other published maps, representing geomorphological landforms, eolian deposits, anthropic terraced slopes, and landslide were used to improve the accuracy and reliability of the map.
Geology and sedimentary facies of the Pliocene succession of the Baronia Mountains (Ariano Basin, southern Italy)
Creators: name: Celma, Claudio Di
name: Rustichelli, Andrea
name: Tondi, Emanuele
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: An up to 1500 m-thick clastic succession, the late Zanclean Baronia Synthem, has been analysed in detail in the Ariano wedge-top Basin (southern Apennine, Italy). In the Baronia Mountains the studied sediments are well exposed and laterally mappable due to young uplift and exhumation and rest unconformably on a complexly deformed pre-Pliocene substratum formed by Triassic to Miocene allochthonous units. The Baronia Synthem has been resolved into seven facies associations that are representative of distinct fluvial, deltaic, nearshore and offshore depositional environments and can be grouped into lowstand, transgressive, and highstand systems tracts. Using an integrated approach comprising original geological field mapping at 1:10,000 scale, conventional sedimentary facies analysis and a sequence stratigraphic approach, this paper provides a detailed description and interpretation of facies associations and new insights on the stratigraphic architecture and the geological history of this portion of the basin fill.
Impact of timing of nintedanib initiation among patients newly diagnosed with idiopathic pulmonary fibrosis
Creators: name: Singer, David
name: Bengtson, Lindsay G. S.
name: Conoscenti, Craig S.
name: Anderson, Amy J.
name: Brekke, Lee
name: Shetty, Sharash S.
name: de Andrade, Joao
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: While nintedanib treatment has been shown to slow the progression of idiopathic pulmonary fibrosis (IPF) in patients across varying levels of lung function, the effect of treatment timing on outcomes has not been examined. We assessed hospitalization risk and medical costs among patients with IPF based on the timing of nintedanib initiation after IPF diagnosis. This retrospective administrative claims study included data from 04/01/2014–09/30/2019 for patients aged ≥40 years who initiated nintedanib within 1 year of IPF diagnosis. Patients were assigned to study cohorts based on the time from IPF diagnosis to nintedanib initiation. All-cause hospitalization and all-cause medical costs were modeled using marginal structural models including inverse probability weights to adjust for both baseline and time-varying characteristics. Of 11,195 patients diagnosed with IPF during the identification period, 449 met the study selection criteria (mean age 72.3 years, 68% male, mean follow-up time 13.3 months). Adjusted hospitalization risk and medical costs both varied significantly by the timing of nintedanib initiation (p p = .020, respectively). Adjusted weighted hospitalization risk was higher among untreated vs. treated patients in months 2–3, months 4–6, and months 7–12 after diagnosis (hazard ratio [95% CI] 1.97 [1.09–3.56], p = .026; 2.62 [1.22–5.63], p = .014; and 5.57 [2.31–13.45], p vs. month 1 (cost ratio [95% CI] 1.69 [1.20–2.38], p = .003). Disease severity could not be assessed because clinical data were unavailable; however, proxies such as oxygen use were included to adjust for between-cohort differences in disease severity. Patients who initiate nintedanib promptly after IPF diagnosis may have reduced hospitalization risk and medical costs compared with those who start treatment later. Additional studies are warranted to improve understanding of the impact of prompt antifibrotic therapy on patient outcomes.
Detoxification of 4-chlorophenol in TiO2 sunlight system: effect of raw and treated solution on seed germination and plants growth of various sensitive vegetables
Creators: name: Elghniji, Kais
name: Salem, Sabrine
name: Mongi Ben Mosbah
name: Elimame Elaloui
name: Moussaoui, Younes
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences

description: The mineralization and detoxification of 4-chlorophenol (4-CP) were studied using a TiO2-paper/sunlight system. The possibility of reusing the photocatalyst was examined to determine the cost effectiveness of the method. Experiments were performed to establish optimum conditions for 4-CP removal. Phytotoxicity of photo-treated and raw 4-CP (100 mg L−1) solutions on seed germination and plant growth were carried out with the aim of water reuse and environment protection. The seeds irrigated with raw 4-CP solution showed lower sprout length while increase in sprout length was observed with the photo-treated solution for tomato (Lycopersicon esculentum), lettuce (Lactuca sativa), onion (Allium cepa), and turnip (Brassica rapa). Plant growth tests with the photo-treated 4-CP solution did not affect the leaf numbers compared to those irrigated with tap water. Photo-treated 4-CP solution can be used for irrigation in agriculture.
Suomalaisten elohopea-altistus elintarvikkeista. Tiivistelmä kansallisen riskinarvioinnin tuloksista
Creators: name: Suomi, Johanna
Publisher: name: Zenodo
Year: 2020
Subjects: subject: mercury
subject: exposure assessment
subject: http://id.agrisemantics.org/gacs/C1470
subject: http://id.agrisemantics.org/gacs/C3980

description: This is a short document for the general reader on the dietary exposure of Finnish children and adults to inorganic mercury and methyl mercury. The results summarized in this document have been presented in more detail in two national risk assessments: https://doi.org/10.5281/zenodo.851785
 and
 http://doi.org/10.5281/zenodo.3772613

description: FI; PDF; johanna.suomi@ruokavirasto.fi
The Future of Genomic Studies Must Be Globally Representative: Perspectives from PAGE
Creators: name: Peters, U.
name: Bien, S.A.
name: Cheng, I.
name: Kenny, E.E.
name: North, K.E.
name: Hodonsky, C.J.
name: Matise, T.C.
name: Wojcik, G.L.
name: Gignoux, C.R.
Publisher: name: Annual Reviews Inc.
Year: 2019

description: The past decade has seen a technological revolution in human genetics that has empowered population-level investigations into genetic associations with phenotypes. Although these discoveries rely on genetic variation across individuals, association studies have overwhelmingly been performed in populations of European descent. In this review, we describe limitations faced by single-population studies and provide an overview of strategies to improve global representation in existing data sets and future human genomics research via diversity-focused, multiethnic studies. We highlight the successes of individual studies and meta-analysis consortia that have provided unique knowledge. Additionally, we outline the approach taken by the Population Architecture Using Genomics and Epidemiology (PAGE) study to develop best practices for performing genetic epidemiology in multiethnic contexts. Finally, we discuss how limiting investigations to single populations impairs findings in the clinical domain for both rare-variant identification and genetic risk prediction.
Geology and sedimentary facies of the Pliocene succession of the Baronia Mountains (Ariano Basin, southern Italy)
Creators: name: Celma, Claudio Di
name: Rustichelli, Andrea
name: Tondi, Emanuele
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: An up to 1500 m-thick clastic succession, the late Zanclean Baronia Synthem, has been analysed in detail in the Ariano wedge-top Basin (southern Apennine, Italy). In the Baronia Mountains the studied sediments are well exposed and laterally mappable due to young uplift and exhumation and rest unconformably on a complexly deformed pre-Pliocene substratum formed by Triassic to Miocene allochthonous units. The Baronia Synthem has been resolved into seven facies associations that are representative of distinct fluvial, deltaic, nearshore and offshore depositional environments and can be grouped into lowstand, transgressive, and highstand systems tracts. Using an integrated approach comprising original geological field mapping at 1:10,000 scale, conventional sedimentary facies analysis and a sequence stratigraphic approach, this paper provides a detailed description and interpretation of facies associations and new insights on the stratigraphic architecture and the geological history of this portion of the basin fill.
Physiography of the Sicilian region (1:250,000 scale)
Creators: name: Fantappiè, Maria
name: Priori, Simone
name: Costantini, Edoardo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Physiographic maps summarize and group the landforms of a territory into homogeneous areas in terms of kind and intensity of the main geomorphological process. These maps are often produced at semi-detailed scales, while examples at the regional scale are much less common. However, because the region is the main administrative level in Europe, physiographic maps can be very useful for land planning in many fields, such as ecological studies, risk maps, and soil mapping. This work presents a methodological example of a regional physiographic map, compiled at a 1:250,000 scale, representing the whole Sicilian region, the largest of the Mediterranean islands. The physiographic units were classified according to the geomorphological processes that were identified by stereo-interpretation of aerial photographs. In addition, information from other published maps, representing geomorphological landforms, eolian deposits, anthropic terraced slopes, and landslide were used to improve the accuracy and reliability of the map.
Gut microbiome composition in the Hispanic Community Health Study/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity
Creators: name: Moon, J.-Y.
name: Daviglus, M.L.
name: Schneiderman, N.
name: Talavera, G.A.
name: Burk, R.D.
name: Wu, M.C.
name: Shaffer, J.
name: Wang, Z.
name: Sotres-Alvarez, D.
name: Thyagarajan, B.
name: McDonald, D.
name: Williams-Nguyen, J.S.
name: Knight, R.
name: Vázquez-Baeza, Y.
name: North, K.E.
name: Kaplan, R.C.
name: Wang, T.
name: Sollecito, C.C.
name: Isasi, C.R.
name: Gellman, M.D.
name: Qi, Q.
name: Usyk, M.
Publisher: name: BioMed Central
Year: 2019

description: Background: Hispanics living in the USA may have unrecognized potential birthplace and lifestyle influences on the gut microbiome. We report a cross-sectional analysis of 1674 participants from four centers of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), aged 18 to 74 years old at recruitment. Results: Amplicon sequencing of 16S rRNA gene V4 and fungal ITS1 fragments from self-collected stool samples indicate that the host microbiome is determined by sociodemographic and migration-related variables. Those who relocate from Latin America to the USA at an early age have reductions in Prevotella to Bacteroides ratios that persist across the life course. Shannon index of alpha diversity in fungi and bacteria is low in those who relocate to the USA in early life. In contrast, those who relocate to the USA during adulthood, over 45 years old, have high bacterial and fungal diversity and high Prevotella to Bacteroides ratios, compared to USA-born and childhood arrivals. Low bacterial diversity is associated in turn with obesity. Contrasting with prior studies, our study of the Latino population shows increasing Prevotella to Bacteroides ratio with greater obesity. Taxa within Acidaminococcus, Megasphaera, Ruminococcaceae, Coriobacteriaceae, Clostridiales, Christensenellaceae, YS2 (Cyanobacteria), and Victivallaceae are significantly associated with both obesity and earlier exposure to the USA, while Oscillospira and Anaerotruncus show paradoxical associations with both obesity and late-life introduction to the USA. Conclusions: Our analysis of the gut microbiome of Latinos demonstrates unique features that might be responsible for health disparities affecting Hispanics living in the USA.
Physiography of the Sicilian region (1:250,000 scale)
Creators: name: Fantappiè, Maria
name: Priori, Simone
name: Costantini, Edoardo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences

description: Physiographic maps summarize and group the landforms of a territory into homogeneous areas in terms of kind and intensity of the main geomorphological process. These maps are often produced at semi-detailed scales, while examples at the regional scale are much less common. However, because the region is the main administrative level in Europe, physiographic maps can be very useful for land planning in many fields, such as ecological studies, risk maps, and soil mapping. This work presents a methodological example of a regional physiographic map, compiled at a 1:250,000 scale, representing the whole Sicilian region, the largest of the Mediterranean islands. The physiographic units were classified according to the geomorphological processes that were identified by stereo-interpretation of aerial photographs. In addition, information from other published maps, representing geomorphological landforms, eolian deposits, anthropic terraced slopes, and landslide were used to improve the accuracy and reliability of the map.
Le EMM Survey Registry et la situation des enquêtes auprès des minorités en France
Creators: name: Winn, Meredith
name: Ando, Yuma
Publisher: name: Zenodo
Year: 2021
Subjects: EMM Survey Registry
ETHMIGSURVEYDATA
survey research
France
migrant minorities
ethnic minorities
FAIR principles
Europe
social sciences

description: On 24 June 2021, COST Action 16111 – ETHMIGSURVEYDATA, FAIRETHMIGQUANT (a French Agence Nationale de la Recherche funded Open Science project based at Sciences Po, CEE), and MiDi - Migration et Diversité (Sciences Po), in partnership with Ined et l'IC Migrations, hosted a webinar in French to showcase the EMM (Ethnic and Migrant Minority) Survey Registry and the French surveys it captures to a French-speaking audience. During this webinar, Meredith Winn, a junior researcher supporting FAIRETHMIGQUANT, highlighted how the EMM Survey Registry can be leveraged to discover and learn about surveys undertaken with EMM (sub)populations in France and across Europe. She also conducted a live demo of the EMM Survey Registry to illustrate its various use cases. -- The EMM Survey Registry is jointly being produced by SSHOC’s Task 9.2 (Ethnic Migration Studies) team of Work Package 9 (Data Communities), in close collaboration with COST Action 16111 – ETHMIGSURVEYDATA (an international network of more than 200 researchers active in the ethnic and migration studies field) and FAIRETHMIGQUANT (a French Agence Nationale de la Recherche funded Open Science project).