cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the co-existence of spot and contract markets: an analysis of quality
Creators: name: Olmos, Marta Fernandez
name: Rosell-Martinez, Jorge
name: Espitia-Escuer, Manuel Antonio
name: Olmos, Marta Fernandez
name: Rosell-Martinez, Jorge
name: Espitia-Escuer, Manuel Antonio
Publisher: name: Unknown
Year: 2008
Subjects: subject: Marketing
subject: FOS: Economics and business

description: The possible co-existence of spot and contract market that can emerge in the presence of quality issues with a number of growers and processors in each stage is something that has largely remained an open question in the literature. This paper is an attempt to fill this void. We use a straightforward two-stage Cournot oligopoly model with specific demand and cost functions. In the first stage, processors decide simultaneously whether or not to set an incentive contract. The second stage is the stage in which growers choose their levels of quantity and quality based on the industry structure developed in the first stage. With the help of numerical simulations we conducted the study of the equilibrium structures. Our results suggest that for a wide range of number of participants in both markets, participation in both markets constitutes a Nash equilibrium for the model.
Raised-Aggregate, Lane-Delineation Stripe
Creators: name: Pigman, Jerry G.
name: Agent, Kenneth R.
Publisher: name: Kentucky Transportation Center, University of Kentucky
Year: 1976
Subjects: subject: Transportation Engineering

description: Experimental raised-aggregate (1/2 inch (13 mm) to 1 inch (25 mm)) traffic stripes were installed on approximately 0.4 mile (644 m) of US 60 just north of the intersection with US 421 in Franklin County. Installation was during June 1974. Aggregate stripes were painted yellow and used as skip lines inside the continuous channelization stripes to indicate no crossing into the two-way, left-turn lane except for turning movements.  Observations indicated that the raised-aggregate stripes had good durability after being exposed to 2 years of wear. During dry, nighttime conditions, the paint stripes were slightly more effective than the aggregate stripes; but raised, pavement markers simulating a paint stripe were superior to either method of delineation. Aggregate stripes provided a substantial improvement over paint stripes during wet, nighttime conditions; but raised, pavement markers were most effective.  The aggregate stripes produced an increase of approximately 3 dBA in the noise level compared to an increase of 5 dBA when driving over raised, pavement markers arranged to simulate paint stripes.  Raised-aggregate stripes were uneconomical when compared to regular paint stripes, thermoplastic striping, and raised, pavement markers. The cost of aggregate stripes would most likely decrease if installation were on a larger scale.
Analyticity of the scattering operator for semilinear dispersive equations
Creators: name: Carles, Rémi
name: Gallagher, Isabelle
Publisher: name: arXiv
Year: 2008
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We present a general algorithm to show that a scattering operator associated to a semilinear dispersive equation is real analytic, and to compute the coefficients of its Taylor series at any point. We illustrate this method in the case of the Schrodinger equation with power-like nonlinearity or with Hartree type nonlinearity, and in the case of the wave and Klein-Gordon equations with power nonlinearity. Finally, we discuss the link of this approach with inverse scattering, and with complete integrability.
description: 29 pages
MPEC 2024-A90 : 2013 JZ28
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Temporary architectures inside static architectures
Creators: name: Claudi De Saint Mihiel, Alessandro
Publisher: name: TECHNE - Journal of Technology for Architecture and Environment
Year: 2020

description: The circumstances that produce architecture have profoundly changed and, among these, precisely those which perceive and use space-time in a different way in comparison with the past. This paper defines a conceptual reference framework by positioning the time factor in relation to the role of the project as an innovative and operational procedural tool in terms of sustainable conversion of cities. The essay aims to investigate the “addition strategy” as a paradigm of architectural grafting to achieve a balanced relationship between temporariness and permanence. It outlines scenarios in which a new design culture is capable of guiding the processes of transformation of the built environment by placing the idea of impermanence in a perspective that is closer to the current socio-technical condition.
description: TECHNE - Journal of Technology for Architecture and Environment, TECHNE 20 (2020): Time and architecture
Mandatory Food Recalls
Creators: name: Thomsen, Michael R.
name: Ollinger, Michael
name: Crandall, Philip G.
name: O'Bryan, Corliss
name: Thomsen, Michael R.
name: Ollinger, Michael
name: Crandall, Philip G.
name: O'Bryan, Corliss
Publisher: name: Unknown
Year: 2008
Subjects: Food Consumption/Nutrition/Food Safety

description: Food recalls are important for two reasons. One is that they mitigate harm when product failures occur. Another is that they augment incentives to invest in safety. When recalls are justified for their mitigation value, it makes sense that regulatory bodies be granted more control of the recall process in order to improve the manner in which recalls are conducted. Such is the stated intent of most proposals for changing the food recall system. However, we show that recalls can be justified by their incentive effect alone. In fact, recalls can be beneficial even when the social value of the harm they mitigate is so small as to be less than the costs of carrying them out. In these cases, it is important that proposals designed to improve the recall process avoid unintended side effects. First, proposals should avoid redirecting regulatory resources towards recall oversight and away from other, more pressing, food safety priorities. Second, it is important to avoid creating an environment in which agencies face a greater need to justify their recall requests. When the mitigation value of recalls is small, this may inadvertently prevent the initiation of recalls that could otherwise play a positive role in aligning incentives for safety.
Schedule quality evaluation for Construction Project Management
Creators: name: Bragadin, Marco Alvise
name: Kahkonen, Kalle
Publisher: name: TECHNE - Journal of Technology for Architecture and Environment
Year: 2020

description: The construction schedule is the most important construction document as it indicates total project duration, project stages and times of activities, costs, logical sequences, quality and safety. Hence, the quality of a phase schedule presented by a contractor must be assessed by the owner’s consultant either before the commencement of works or during the bidding phase. Only few international standards concerning schedule quality exist, and most of them are not specific for construction. A construction-oriented schedule quality evaluation procedure, based upon a set of 75 requirements has been proposed. Three different versions of a construction schedule for a case study of a seismic rehabilitation project have been evaluated with the aim of performing the proposed method’s proof-of-concept.
description: TECHNE - Journal of Technology for Architecture and Environment, TECHNE 20 (2020): Time and architecture
Toward permanent emergency: Design-Build-Living Reversible
Creators: name: Antonini, Ernesto
name: Giglio, Francesca
name: Boeri, Andrea
Publisher: name: TECHNE - Journal of Technology for Architecture and Environment
Year: 2020

description: Temporary life has become a topic of discussion in the architectural debate concerning both post-catastrophic events and critical peaks in the housing demand. The strategies adopted to deal with emergency contexts can provide a stimulating testing ground that yields suitable approaches, which can be applied when facing the present permanent environmental crisis at a global scale. This is particularly true for certain post-catastrophe strategies adopted in the poorest countries, where local resources and Low-Tech processes can respond to housing and climate needs, compensating for the limited resources available with the intelligence of design solutions. Some criteria established to map the relationship between quality performance and durability of products are later applied to the critical analysis of three emblematic case studies of emergency housing in extreme contexts to identify their innovation content.
description: TECHNE - Journal of Technology for Architecture and Environment, TECHNE 20 (2020): Time and architecture
Do Inventory and Time-to-Delivery Effects Vary Across Futures Contracts? Insights from a Smoothed Bayesian Estimator
Creators: name: Karali, Berna
name: Dorfman, Jeffrey H.
name: Thurman, Walter N.
name: Karali, Berna
name: Dorfman, Jeffrey H.
name: Thurman, Walter N.
Publisher: name: Unknown
Year: 2008
Subjects: subject: Marketing
subject: FOS: Economics and business
subject: volatility
subject: theory of storage
subject: futures markets
subject: Bayesian econometrics
subject: lumber

description: We apply a new Bayesian approach to multiple-contract futures data to allow the inventory and time-to-delivery effects on volatility to vary across contracts. We find a varying negative relationship between lumber inventories and lumber futures price volatility. The inventory effect is smaller for the most recent contracts possibly due to increasing inventories over time. While this approach reveals the downward bias on the inventory effect introduced by restricting this parameter across contracts, it does not change the time-to-delivery effect.
description: Replaced with revised version of paper 07/15/08.
MPEC 2024-A91 : 2015 AK1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Holomorphic Motions and Normal Forms in Complex Analysis
Creators: name: Jiang, Yunping
Publisher: name: arXiv
Year: 2005
Subjects: subject: Dynamical Systems (math.DS)
subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 37F99, 32H02

description: We give a brief review of holomorphic motions and its relation with quasiconformal mapping theory. Furthermore, we apply the holomorphic motions to give new proofs of famous Konig's Theorem and Bottcher's Theorem in classical complex analysis.
Gaining Environmental Benefits from Positive Land Management: Practical Experience from the North Kent Marshes
Creators: name: Merricks, Philip
name: Merricks, Philip
Publisher: name: Unknown
Year: 2002
Subjects: Farm Management
Land Economics/Use

description: Whilst Environmental Cross Compliance may be one way of reducing environmental disbenefits or negative externalities, it is argued that a better way of providing environmental benefits or positive externalities is to clarify the objectives of environmental policy and to link payments more directly to the achievement of those objectives. Experience at Elmley shows how this has been achieved in the UK. The 1200 ha Elmley Estate is managed both as a working farm and for wildlife as the Elmley National Nature Reserve. The whole estate falls within the North Kent Marshes Environmentally Sensitive Area. The Estate now supports a greater number of breeding waders than any other lowland wet grassland site in England. This growth in wildlife has been achieved through the positive management of water levels and the grazing of sheep and cattle together with other land management techniques. It provides a successful example of practical and integrated farm management producing prime quality store livestock and greatly increased wildlife.
Additional file 1 of Longitudinal changes of frailty in 8 years: comparisons between physical frailty and frailty index
Creators: name: Hwang, An-Chun
name: Lee, Wei-Ju
name: Huang, Nicole
name: Chen, Liang-Yu
name: Peng, Li-Ning
name: Lin, Ming-Hsien
name: Chou, Yiing-Jenq
name: Chen, Liang-Kung
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: Computational Biology

description: Additional file 1: Supplementary Table 1. Modified frailty phenotype and corresponding variables in the Taiwan Longitudinal Study on Aging. Supplementary Table 2. Frailty index variables and corresponding variables in the Taiwan Longitudinal Study on Aging. Supplementary Table 3. Major time-dependent variables by trajectory groups. Supplementary Table 4. Logistic regression between associated factors and frailty trajectory groups. Supplementary Figure 1. Major variables transitions among frailty phenotype trajectory groups (A–E).
Wolf-Rayet galaxies in SDSS-IV MaNGA. II. Metallicity dependence of the high-mass slope of the stellar initial mass function
Creators: name: Liang, Fu-Heng
name: Li, Cheng
name: Li, Niu
name: Zhou, Shuang
name: Yan, Renbin
name: Mo, Houjun
name: Zhang, Wei
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: As hosts of living high-mass stars, Wolf-Rayet (WR) regions or WR galaxies are ideal objects for constraining the high-mass end of the stellar initial mass function (IMF). We construct a large sample of 910 WR galaxies/regions that cover a wide range of stellar metallicity (from Z~0.001 up to Z~0.03), by combining three catalogs of WR galaxies/regions previously selected from the SDSS and SDSS-IV/MaNGA surveys. We measure the equivalent widths of the WR blue bump at ~4650 A for each spectrum. They are compared with predictions from stellar evolutionary models Starburst99 and BPASS, with different IMF assumptions (high-mass slope α of the IMF ranging from 1.0 up to 3.3). Both singular evolution and binary evolution are considered. We also use a Bayesian inference code to perform full spectral fitting to WR spectra with stellar population spectra from BPASS as fitting templates. We then make model selection among different α assumptions based on Bayesian evidence. These analyses have consistently led to a positive correlation of IMF high-mass slope α with stellar metallicity Z, i.e. with steeper IMF (more bottom-heavy) at higher metallicities. Specifically, an IMF with α=1.00 is preferred at the lowest metallicity (Z~0.001), and a Salpeter or even steeper IMF is preferred at the highest metallicity (Z~0.03). These conclusions hold even when binary population models are adopted.
description: 22 pages, 11 figures, accepted by ApJ
Risk Analyses of Disposal of Pig Carcasses Smaller Than 40 KG in The Netherland
Creators: name: Mul, Monique F.
name: Bokma-Bakker, Martien H.
name: Eijick, Ineke
name: Mul, Monique F.
name: Bokma-Bakker, Martien H.
name: Eijick, Ineke
Publisher: name: Unknown
Year: 2002
Subjects: subject: Livestock Production/Industries
subject: Risk analyses
subject: pig
subject: carcasses
subject: disposal
subject: spread of disease
subject: odour nuisance
subject: pig farms
subject: rendering plant

description: A study based on the literature, an on- farm audit and expert knowledge, was carried out to determine 1) the risks of spread of animal diseases among farms; 2) odour nuisance due to carcasses at the rendering plant; and 3) measurements to reduce these risks. It was concluded that the possible risks of spread of animal diseases among farms due to the removal of carcasses mainly has to do with the entrance of the place from where the carcasses are collected by the driver of the truck , the contact of the grab of the haulier with the cadaver container or place and driving with the haulier which is not fully closed. The true size of the risk of spread of disease is unknown and is probably different for each pathogen. Strict hygiene measurements by the driver and farmer can reduce the risk of spread of animal diseases due to cadaver removal. According to the interviewees at the expert assessment session, the odour nuisance at the rendering plant due to carcasses is mainly caused by bacterial conversion of proteins. Cooling of carcasses contribute to the slowing down of the conversions. No unambigious answer could be obtained as to the cooling temperature: not lower than -7°C because of the processing at the rendering plant and preferably not higher than 5°C. Frequent removal of carcasses from the farms and a quick handling at the rendering plant may also reduce odour nuisance at the rendering plant.
Metadata record for the manuscript: Clinical Application of a Lung Cancer Organoid (Tumoroid) Culture System
Creators: name: Yokota, Etsuko
name: Iwai, Miki
name: Yukawa, Takuro
name: Yoshida, Masakazu
name: Naomoto, Yoshio
name: Haisa, Minoru
name: Monobe, Yasumasa
name: Nagio Takigawa
name: Minzhe Guo
name: Maeda, Yutaka
name: Fukazawa, Takuya
name: Yamatsuji, Tomoki
Publisher: name: figshare
Year: 2021
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Summary
 This metadata record provides details of the data supporting the claims of the related manuscript: “Clinical Application of a Lung Cancer Organoid (Tumoroid) Culture System”. The related study demonstrated the use of AO (airway organoid) media developed by the Clevers laboratory to generate 3 lung tumoroid lines for long-term culture (>13 months) from 41 lung cancer cases (primary or metastatic). Type of data: RNA sequencing, exome sequencing Subject of data: Homo sapiens, Human lung adenocarcinoma cell lines H1395 and H1666 Sample size: Three cases of lung tumoroids were analyxed from 41 cases of lung cancer Data access The RNA-seq data are openly available in the Gene Expression Omnibus repository under accession https://identifiers.org/geo:GSE157659, and the exome-seq data are openly available in the Sequence Read Archive repository under accession code https://identifiers.org/ncbi/bioproject:PRJNA689916. Corresponding author(s) for this study Takuya Fukazawa, M.D., Ph.D., Department of General Surgery, Kawasaki Medical School, Okayama, Japan, 700-8505. E-mail: fukazawat@med.kawasaki-m.ac.jp
 Study approval  The research protocol was approved by the Ethics Committee of Kawasaki Medical School (Reference Number: 3171-1). All patients participating in this study signed informed consent forms that were approved by the responsible authority.
Harmonic Analysis in d-dimensional Superconformal Field Theory
Creators: name: Buric, Ilija
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Superconformal blocks and crossing symmetry equations are among central ingredients in any superconformal field theory. We review the approach to these objects rooted in harmonic analysis on the superconformal group that was put forward in [J. High Energy Phys. 2020 (2020), no. 1, 159, 40 pages, arXiv:1904.04852] and [J. High Energy Phys. 2020 (2020), no. 10, 147, 44 pages, arXiv:2005.13547]. After lifting conformal four-point functions to functions on the superconformal group, we explain how to obtain compact expressions for crossing constraints and Casimir equations. The later allow to write superconformal blocks as finite sums of spinning bosonic blocks.
description: published version
Grammatical elicitation: Classifiers and narrative transcription
Creators: name: Calmo Jerónimo, Brenda
name: Lemon, Tyler
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2020
Subjects: subject: mvj

description: Attempting to determine what conditions the occurrence of classifiers. This session focuses on the animal classifier 'xal', testing whether definiteness, possession, numeral modification, or adjectival modification force its appearance or absence.
Development of Strategic Consultancy to Farm Managers: Experience from an Action Research Approach
Creators: name: Lund, Mogens
name: Larsen, Torben Ulf
name: Lund, Mogens
name: Larsen, Torben Ulf
Publisher: name: Unknown
Year: 2002
Subjects: Farm Management

description: A Danish action research approach to the development of strategic consultancy to farm managers is presented. The development principles adopted include separate investigations of the content and process of strategic consultancy resulting in the formulation of a development matrix and a procedure for knowledge transformations. The project activities were carried out by a self-organised team group with participants from both consultancy and research organisations. The produced knowledge and strategic tools have been tested in a number of farm cases by local consultants and the implemented evaluation programme indicates that the needs of farmers have been fulfilled and the local consultants have increased their strategic competences. Key words: Action research, strategic consultancy, process and content, development matrix, self-organisation, knowledge transformations, complex learning and consultancy processes.
Linear Stability Analysis of a Magnetic Rotating Disk with Ohmic Dissipation and Ambipolar Diffusion
Creators: name: Das, Indrani
name: Basu, Shantanu
Publisher: name: arXiv
Year: 2020
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We perform a linear analysis of the stability of isothermal, rotating, magnetic, self-gravitating sheets that are weakly ionized. The magnetic field and rotation axis are perpendicular to the sheet. We include a self-consistent treatment of thermal pressure, gravitational, rotational, and magnetic (pressure and tension) forces together with two nonideal magnetohydrodynamic (MHD) effects (Ohmic dissipation and ambipolar diffusion) that are treated together for their influence on the properties of gravitational instability for a rotating sheet-like cloud or disk. Our results show that there is always a preferred length scale and associated minimum timescale for gravitational instability. We investigate their dependence on important dimensionless free parameters of the problem: the initial normalized mass-to-flux ratio $μ_0$, the rotational Toomre parameter $Q$, the dimensionless Ohmic diffusivity $\tildeη_{\rm OD,0}$, and the dimensionless neutral-ion collision time $\tildeτ_{\rm{ni,0}}$ that is a measure of the ambipolar diffusivity. One consequence of $\tildeη_{\rm OD,0}$ is that there is a maximum preferred lengthscale of instability that occurs in the transcritical ($μ_0 \gtrsim 1$) regime, qualitatively similar to the effect of $\tildeτ_{\rm{ni,0}}$, but with quantitative differences. The addition of rotation leads to a generalized Toomre criterion (that includes a magnetic dependence) and modified lengthscales and timescales for collapse. When nonideal MHD effects are also included, the Toomre criterion reverts back to the hydrodynamic value. We apply our results to protostellar disk properties in the early embedded phase and find that the preferred scale of instability can significantly exceed the thermal (Jeans) scale and the peak preferred fragmentation mass is likely to be $\sim 10- 90 \ M_{\rm Jup}$.
description: 30 pages, 17 figures. Accepted for publication by ApJ
Farming in the "New Economy" : An Australian Perspective
Creators: name: McGregor, Murray J.
name: Bent, Martin J.M.
name: McGregor, Murray J.
name: Bent, Martin J.M.
Publisher: name: Unknown
Year: 2002
Subjects: Farm Management

description: Barriers to trade between countries have reduced through the general Agreement on Tariffs and Trade (GATT) and the World Trade Organisation (WTO). The nature of trade between businesses is also changing dramatically through developments in Information Technology but also due to adoption of quality assurance and new approaches to supply chain management. The impacts of this "New Economy" vary around the world. This paper considers the implications of these developments for Australian farmers. Whilst these changes can be regarded as generally advantageous to Australian farmers, they may be disadvantaged in some areas because of the relatively small size of the Australian farming sector, its geographical dispersion, the advent of a range of new technologies and the structure of agribusinesses. The potential changes to the nature of farming and farm management skills are discussed.
Trends and Future Perspectives of Organized Farms in Japan
Creators: name: Nagaki, Masakazu
name: Nagaki, Masakazu
Publisher: name: Unknown
Year: 2002
Subjects: Farm Management

description: This paper discussed the types of farm enterprises, recent trends of them entry into and establishment of farming business in Japan. The cooperative farm corporations (CFCs) that are controlled by the Agricultural Cooperatives Act have been distinguished from the enterprises that are controlled by the Code of Commerce. Distinctions and characteristics are evaluated along the historical backgrounds. Not many but young willing farmers are increasingly converting their business form into CFCs and expanding business size either by horizontal or vertical ways. Agribusiness enterprises are entering to include the production. However, their interest products are limited. Particularly staple food supply is entrusted much to CFCs and traditional family farms as usual. Emphasis must be placed to encourage CFCs since CFCs play important public roles in the rural community. One suggestion is to make arrangements so that CFCs can join enterprises and work together complementary.
Social Capital and Farmers' Willingness to Adopt Countryside Stewardship Schemes
Creators: name: Mathijs, Erik
name: Mathijs, Erik
Publisher: name: Unknown
Year: 2002
Subjects: Farm Management

description: The EU provides farmers with incentives to adopt Countryside Stewardship Schemes (CSS) using subsidies in the framework of the agri-environmental regulation of the EU (2078/92), now included in the more general regulation on rural development In this paper, a case study of 36 farmers in the village of Bierbeek, was carried out to investigate the determinants of the willingness to adopt a scheme involving taking care of arable field margins in particular. Bivariate and multivariate logit analysis confirmed not only the importance of personal, structural and financial factors, but also showed the importance of social capital. Farmers who are more open to both professional and nonprofessional contacts are more likely to adopt a CSS. Hence, government and extension agencies should undertake more efforts to involve farmers as much as possible in activities of professional, but also non-professional, nature to stimulate them to adopt sustainable farming practices.
Functional analysis of the escherichia coli hemolysin signal sequence by random oligonucleotide mutagenesis
Creators: name: Hui, David
Publisher: name: University of British Columbia
Year: 2009

description: The E. coli hemolysin is an RTX toxin that is secreted by an ATP-binding cassette transporter complex consisting of HlyB, HlyD, and TolC. Translocation of this protein is dependent on a C-terminal signal sequence located within the last 60 amino acids. Previous studies demonstrated that the signal sequence of a similar toxin, P. haemolytica leukotoxin, could replace that of hemolysin and was efficiently transported. While the two signal sequences share little primary sequence similarities, circular dichroism and ¹⁵N nuclear magnetic resonance revealed a conserved helix-strand-helix motif, leading to the hypothesis that this motif is important for efficient secretion. A previous study using helical variants generated by a combinatorial approach suggested that any one of a large number of sequences that yielded a predicted amphiphilic helix in the upstream helical region is sufficient for transport (Morden, 1998). To further elucidate structural requirements of the signal sequence, the helix-strandhelix motif was divided into three regions (α1-linker- α2) and each was subjected to random oligonucleotide mutagenesis analysis. The last 16 residues of the extreme Cterminus was also analyzed using two contiguous random libraries (Cterml and Cterm2). This approach replaced the target region with a random sequence, and the presence or absence of any critical element(s) within each region was deduced by measuring the level of secretion of the mutant population. Based on the results from the five random libraries and the al helical library, a two-domain functional model of the hemolysin signal sequence was proposed. The first domain consists of the α1 and the linker regions. An amphiphilic helical structure in the al region appears to be both sufficient and required for transport. The second domain involves the last 8 residues of the signal sequence, and hydrophobicity in this region appears to be a major determinant of efficient transport. Connecting the two is a stretch of 19 residues, with no specific requirements. This is a surprise since this stretch of amino acids contains the second helix of the helix-strand-helix motif. Nevertheless, this study supports the model that the important features of the signal sequences are secondary structure (i.e. amphiphilic helix) and general biophysical property (i.e. hydrophobicity) rather than primary sequence.
Proton-Antiproton Annihilation in Baryonium
Creators: name: Ding, Gui-Jun
name: Yan, Mu-Lin
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A possible interpretation of the near-threshold enhancement in the $(p\bar{p})$-mass spectrum in $J/ψ{\to}γp{\bar p}$ is the of existence of a narrow baryonium resonance X(1860). Mesonic decays of the $(p\bar{p})$-bound state X(1860) due to the nucleon-antinucleon annihilation are investigated in this paper. Mesonic coherent states with fixed $G$-parity and $P$-parity have been constructed . The Amado-Cannata-Dedoder-Locher-Shao formulation(Phys Rev Lett. {\bf 72}, 970 (1994)) is extended to the decays of the X(1860). By this method, the branch-fraction ratios of $Br(X\to η4π)$, $Br(X\to η2π)$ and $Br(X\to 3η)$ are calculated. It is shown that if the X(1860) is a bound state of $(p\bar{p})$, the decay channel ($X\to η4π)$ is favored over $(X\to η2π)$. In this way, we develop criteria for distinguishing the baryonium interpretation for the near-threshold enhancement effects in $(p\bar{p})$-mass spectrum in $J/ψ{\to}γp{\bar p}$ from other possibilities. Experimental checks are expected. An intuitive picture for our results is discussed.
description: 19 pages, 3 figures
Commutatively Deformed General Relativity: Foundations, Cosmology, and Experimental Tests
Creators: name: de Vegvar, P. G. N.
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: An integral kernel representation for the commutative $\star$-product on curved classical spacetime is introduced. Its convergence conditions and relationship to a Drin'feld differential twist are established. A $\star$-Einstein field equation can be obtained, provided the matter-based twist's vector generators are fixed to self-consistent values during the variation in order to maintain $\star$-associativity. Variations not of this type are non-viable as classical field theories. $\star$-Gauge theory on such a spacetime can be developed using $\star$-Ehresmann connections. While the theory preserves Lorentz invariance and background independence, the standard ADM $3+1$ decomposition of 4-diffs in general relativity breaks down, leading to different $\star$-constraints. No photon or graviton ghosts are found on $\star$-Minkowski spacetime. $\star$-Friedmann equations are derived and solved for $\star$-FLRW cosmologies. Big Bang Nucleosynthesis restricts expressions for the twist generators. Allowed generators can be constructed which account for dark matter as arising from a twist producing non-standard model matter field. The theory also provides a robust qualitative explanation for the matter-antimatter asymmetry of the observable Universe. Particle exchange quantum statistics encounters \emph{thresholded} modifications due to violations of the cluster decomposition principle on the nonlocality length scale $\sim10^{3-5} \,L_P$. Precision Hughes-Drever measurements of spacetime anisotropy appear as the most promising experimental route to test deformed general relativity.
description: Revised and published version
Topological properties of black holes in five-dimensional gauged supergravity
Creators: name: He, Yucheng
name: Lei, Changxiang
name: Chen, Deyou
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, we study the topological properties of five-dimensional rotating charged black holes in different ensembles.The topological numbers for the black holes are gotten in the grand canonical and canonical ensembles, which are 1. When the charge and cosmological constant disappear, their topological numbers are 0. When the pressure is lower than the critical pressure, the phase transition exists in the canonical ensemble. However, the phase transition also exists in the grand canonical ensemble when the pressure is higher than the critical pressure and two independent rotational parameters are $a=1$ and $b=-1$. This may be due to the fact that the values of the rotational parameters change the supersymmetry of the black hole and lead to the phase transition.
description: 15 pages
Lehmann, Arno (Hrsg.), Gottes Volk in vielen Ländern
Creators: name: Mildenberger, Michael
Publisher: name: Ökumenische Rundschau
Year: 2025

description: Ökumenische Rundschau, Bd. 32 Nr. 2 (1983): Ökumenische Rundschau, Band 32, Heft 2
Consumers' Perception of Milk Safety
Creators: name: Novoselova, Tatiana A.
name: Meuwissen, Miranda P.M.
name: Van Der Lans, Ivo A.C.M.
name: Valeeva, Natasha I.
name: Novoselova, Tatiana A.
name: Meuwissen, Miranda P.M.
name: Van Der Lans, Ivo A.C.M.
name: Valeeva, Natasha I.
Publisher: name: Unknown
Year: 2002
Subjects: subject: Food Consumption/Nutrition/Food Safety
subject: food safety
subject: questionnaire survey
subject: risk attitudes
subject: risk perceptions
subject: willingness to pay
subject: willingness to buy.

description: Several times during the last decade consumers have been warned about different incidents concerning food safety, like, salmonella in eggs, cheese and poultry, and pesticides residues in tomatoes. The problem of food safety is still to be a largely latent concern for consumers. The main research goal of this paper is to investigate consumers' risk attitudes and risk perceptions concerning milk safety and to estimate their willingness to pay for extra-safe milk. The data was collected in the Netherlands using a mail survey. 211 usable questionnaires (26%) were returned. Results show that, in general, consumers are not concerned about the safety of milk. However, the results of consumers' perceptions of the "riskiness of milk contamination" for vulnerable groups of people show that babies are considered to be more sensitive to different sources of contamination than other groups. This study supports the results of previous food safety studies showed that consumers are willing to pay a price premium to the traditional purchase price to avoid some perceived risks. 58% of respondents are willing to pay an additional price for extra-safe milk. The conjoint experiment results indicate that the most important factors for consumers' preference are risk of contamination and presence of a label. Based on a conjoint analysis four segments of respondents were distinguished: "Balanced Shoppers"; "Safety-Seekers"; "Safety-Indifferent"; and "Extreme-Safety Seekers".
Metadata record for the manuscript: Cisplatin with or without Rucaparib after preoperative chemotherapy in patients with triple-negative or BRCA mutated breast cancer
Creators: name: Maitri Kalra
name: Tong, Yan
name: Jones, David R.
name: Walsh, Tom
name: Danso, Michael A.
name: Ma, Cynthia X.
name: Silverman, Paula
name: Mary-Claire King
name: Badve, Sunil S.
name: Perkins, Susan M.
name: Miller, Kathy D.
Publisher: name: figshare
Year: 2021
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences
subject: Diseases
subject: Cancer
subject: 111203 Cancer Genetics
subject: FOS: Clinical medicine
subject: 111299 Oncology and Carcinogenesis not elsewhere classified

description: Summary
 This metadata record provides details of the data supporting the claims of the related manuscript: “Cisplatin with or without Rucaparib after preoperative chemotherapy in patients with triple-negative or BRCA mutated breast cancer ”. The related study tested the impact of DNA-damaging chemotherapy alone or with poly(ADP-ribose) polymerase (PARP) inhibition in the high-risk population of patients with triple negative breast cancer (TNBC) who have residual disease after neoadjuvant therapy. Type of data: DNA sequencing, clinical data Subject of data: Homo sapiens Sample size: Sample size was based on an estimated 2 year DFS of 40% in the control arm. Researchers targeted a HR 0.5 (corresponding to a 63.2% 2 year DFS) in the experimental arm with 80% power using a one-sided log rank test at the 01 significance level. Assuming accrual over 13-18 months and exponential survival 102 patients were required for the primary analysis. Total sample size was increased to allow for the planned safety run in cohorts and for drop-outs. Population characteristics: women, median age 47.5 years with a median residual tumour measuring 1.9 cm and involving 1 axillary node Recruitment: Subjects were recruited by participating investigators at 24 US sites. Trial registration number: NCT01074970 Data access The data are not publicly available for the following reason: data contain information that could compromise research participant privacy. However, the data can be made available upon reasonable request to the corresponding author. A list of all data files generated as part of the related study is available as part of this figshare data record in the file ‘Kalra_et_al_2021_underlying_data_availability.xlsx’. Corresponding author(s) for this study Dr. Kathy Miller Joseph E. Walther Hall 980 W. Walnut, Room C218E Indianapolis, IN 46202 Phone (317)948-3855 kathmill@iu.edu
 Study approval  Hoosier Cancer Research Network. IU Simon Cancer Center Data and Safety Monitoring Board.
Outbursts Upon Cooling of Low-Temperature Binary Mixtures: Experiments and Their Planetary Implications
Creators: name: Raposa, S. M.
name: Engle, A. E.
name: Tan, S. P.
name: Grundy, W. M.
name: Hanley, J.
name: Lindberg, G. E.
name: Umurhan, O. M.
name: Steckloff, J. K.
name: Thieberger, C. L.
name: Tegler, S. C.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: For many binary mixtures, the three-phase solid-liquid-vapor equilibrium curve has intermediate pressures that are higher than the pressure at the two pure triple points. This curve shape results in a negative slope in the high-temperature region near the triple point of the less volatile component. When freezing mixtures in the negative slope regime, fluid trapped below confined ice has latent heat released with more vapor upon cooling, and thus increases in pressure. If the rising pressure of the confined fluid overcomes the strength of the confining solid, which may be its own ice, it can produce an abrupt outburst of material and an increase in the system's overall pressure. Here, we report experimental results of freezing-induced outbursts occurring in the N2/CH4, CO/CH4, and N2/C2H6 systems, and provide insight into the phenomenon through a thermodynamics perspective. We also propose other binary systems that may experience outbursts and explore the geological implications for icy worlds like Titan, Triton, Pluto and Eris, as well as rocky bodies, specifically Earth and Mars.
description: 30 pages, 8 figures
Stability analysis of rotating beams rubbing on an elastic circular structure
Creators: name: Lesaffre, Nicolas
name: Sinou, Jean-Jacques
name: Thouverez, Fabrice
Publisher: name: arXiv
Year: 2008
Subjects: subject: Classical Physics (physics.class-ph)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: This paper presents the stability analysis of a system composed of rotating beams on a flexible, circular fixed ring, using the Routh-Hurwitz criterion. The model displayed has been fully developed within the rotating frame by use of an energy approach. The beams considered possess two degrees of freedom (dofs), a flexural motion as well as a traction/compression motion. In-plane deformations of the ring will be considered. Divergences and mode couplings have thus been underscored within the rotating frame and in order to simplify understanding of all these phenomena, the dofs of the beams will first be treated separately and then together. The dynamics of radial rotating loads on an elastic ring can create divergence instabilities as well as post-critical mode couplings. Moreover, the flexural motion of beam rubbing on the ring can also lead to mode couplings and to the locus-veering phenomenon. The presence of rubbing seems to make the system unstable as soon as the rotational speed of the beams is greater than zero. Lastly, the influence of an angle between the beams and the normal to the ring's inner surface will be studied with respect to system stability, thus highlighting a shift frequency phenomenon.
Neutron stars with Bogoliubov quark-meson coupling model
Creators: name: Rabhi, Aziz
name: Providência, Constança
name: Moszkowski, Steven A.
name: da Providência, João
name: Bohr, Henrik
Publisher: name: arXiv
Year: 2020
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A quark-meson coupling model based on the quark model proposed by Bogoliubov for the description of the quark dynamics is developed and applied to the description of neutron stars. Starting from a su(3) symmetry approach, it is shown that this symmetry has to be broken in order to satisfy the constraints set by the hypernuclei and by neutron stars. The model is able to describe observations such as two solar mass stars or the radius of canonical neutron stars within the uncertainties presently accepted. If the optical potentials for $Λ$ and $Ξ$ hyperons in symmetric nuclear matter at saturation obtained from laboratory measurements of hypernuclei properties are imposed the model predicts no strangeness inside neutron stars.
description: 14 pages, 4 figures, 1 table, revised and re submitted for publication to Physical Review C journal
Farm Sector Capital Structure Indicators in Estonia
Creators: name: Nurmet, Maire
name: Roots, Juri
name: Huirne, Ruud B.M.
name: Nurmet, Maire
name: Roots, Juri
name: Huirne, Ruud B.M.
Publisher: name: Unknown
Year: 2002
Subjects: Farm Management

description: Empirical tests are provided to determine the optimal leverage adjustment in transitional economy. Econometric model of agricultural firm capital structure is specified and estimated in order to analyze, how different factors affect agricultural firm's capital structure. Issues in financial structure, that under particular ownership type should be considered in responding to changes in the operating environment, are found. The evidence suggests that profit, income tax, depreciation have an influence on increase in financial leverage. Results indicate that increase in firm's profits may induce firms to increase financial risk through capital structure adjustments.
Consumer Willingness to Pay for Organic Products in Urban Turkey
Creators: name: Akgungor, Sedef
name: Miran, Bulent
name: Abay, Canan
name: Akgungor, Sedef
name: Miran, Bulent
name: Abay, Canan
Publisher: name: Unknown
Year: 2007
Subjects: subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Organic fruits and vegetables
subject: consumer preferences
subject: willingness to pay
subject: perceived risk

description: The objective of the paper is to present the preliminary results of the survey project whose aim is to explore the Turkish consumer's perceptions regarding food safety and the tradeoff they make between chemical residues and cosmetic quality in fresh fruit and vegetable marketing chain. Previous research in Turkey contends that Turkey organic food exports are growing and that there is a small but growing domestic market. A lacking component of the prevailing studies is that none of the studies have focused on the cosmetic quality component of organic products. Another aspect that is missing in the previous studies is that it is not possible to make inferences for the Turkish urban consumers due to designs in sampling and population definition. The aim of the project will be fulfilled by estimating a representative sample of Turkish urban consumer's willingness to pay for reduced chemical residues in food and the tradeoff they make between cosmetic quality and food safety. The data is obtained through consumer focus group studies and consumer surveys with a representative sample of Turkish urban population. Higher income and educated individuals show more interest and have more knowledge regarding organic products. The choice for organic products is due to consumer perception that organic products have higher nutritional value and carry low health risk. It is also found that consumers do not perceive that organic products have higher prices than conventional counterparts. Consumer willingness to pay for products with organic labels and certified products is up to 36%, thus representing a strong demand potential for organic products in Turkey's urban markets.