Additional file 2 of Interventions to control nosocomial transmission of SARS-CoV-2: a modelling study
Creators: name: Pham, Thi Mui
name: Tahir, Hannan
name: van de Wijgert, Janneke H. H. M.
name: Van der Roest, Bastiaan R.
name: Ellerbroek, Pauline
name: Bonten, Marc J. M.
name: Bootsma, Martin C. J.
name: Kretzschmar, Mirjam E.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 2: Supplementary results. (1) Additional results for the main analysis: Table S1. Outcome measures for baseline and intervention scenarios. Figure S1. Positivity rate of screening interventions for different prevalence ranges. Figure S2. Positivity rate of contact tracing interventions for different prevalence ranges. Figure S3. Proportion of detected nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario. Figure S4. Transmission route contributions for nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario. Figure S5. Proportion of transmissions from HCWs and from patients for each simulation scenarios. Figure S6. Proportion of nosocomial transmissions in COVID- and non-COVID wards for each simulation scenario. Figure S7. Proportion of transmissions during different infection states for each simulation scenario. (2) Results of sensitivity analyses: Figure S8. Effective reproduction numbers for the nosocomial spread of the SARS-CoV-2 variant for each simulation scenario assuming 50% effective PPE. Figure S9. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario assuming 50% effective PPE. Figure S10. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario assuming 50% effective PPE. Figure S11. Effective reproduction numbers for the nosocomial spread of the SARS-CoV-2 variant for each simulation scenario assuming 70% effective PPE. Figure S12. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario assuming 70% effective PPE. Figure S13. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario assuming 70% effective PPE. Figure S14. Effective reproduction numbers for the nosocomial spread of the SARS-CoV-2 variant for each simulation scenario assuming equal reproduction numbers for symptomatically and asymptomatically infected individuals R_S=1·95 and R_A=1·95. Figure S15. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario assuming equal reproduction numbers for symptomatically and asymptomatically infected individuals R_S=1·95 and R_A=1·95. Figure S16. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario assuming equal reproduction numbers for symptomatic and asymptomatic individuals R_S=1·95 and R_A=1·95. Figure S17. Effective reproduction numbers for each simulation scenario assuming reproduction numbers of the wild-type SARS-CoV-2 variant. Figure S18. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario assuming reproduction numbers of the wild-type SARS-CoV-2 variant. Figure S19. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario assuming reproduction numbers of the wild-type SARS-CoV-2 variant. Figure S20. Effective reproduction numbers for the nosocomial spread of the SARS-CoV-2 variant for each simulation scenario assuming higher contact rates between HCWs. Figure S21. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario assuming higher contact rates between HCWs. Figure S22. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario assuming higher contact rates between HCWs. Figure S23. Effective reproduction numbers for the nosocomial spread of the SARS-CoV-2 variant for the high test sensitivity scenario. Figure S24. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario for the high test sensitivity scenario. Figure S25. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario for the high test sensitivity scenario. Figure S26. Effective reproduction numbers for the nosocomial spread of the SARS-CoV-2 variant for the low test sensitivity scenario. Figure S27. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario for the low test sensitivity scenario. Figure S28. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario for the low test sensitivity scenario. Figure S29. Effective reproduction numbers for the nosocomial spread of the SARS-CoV-2 variant for the recovery time sensitivity scenario. Figure S30. Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario for the recovery time sensitivity scenario. Figure S31. Daily percentage of absent HCWs during the hospital epidemic for each simulation scenario for the recovery time sensitivity scenario.