cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: The size of things II
title: Movement, features, and interpretation
titleType: Subtitle
Creators: name: Shen, Zheng (Ed.)
name: Laszakovits, Sabine (Ed.)
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: size effects in movement
subject: agreement
subject: interpretation
subject: 400 Sprache::410 Linguistik::410 Linguistik

description: Synopsis: This book focuses on the role size plays in grammar. Under the umbrella term size fall the size of syntactic projections, the size of feature content, and the size of reference sets. This Volume II discusses size effects in movement, agreement, and interpretation while the contributions in Volume I focus on size and structure building. Part I of Volume II investigates how size interacts with head movement and various phrasal movement including left branch extraction, object shift, tough movement, and multiple wh movement. Part II of this volume discusses the role size plays in agreement and morphology-related matters like allomorphy. Contributions in Part III focus on semantic-oriented issues, in particular the size of reference domains and NPI licensing. The languages covered in this volume include American Sign Language, Bosnian-Croatian-Serbian and various other Slavic languages, German, Icelandic, dialects of Italian, Japanese, Nancowry, Panoan languages, and Tamil.
Infinite order $Ψ$DOs: Composition with entire functions, new Shubin-Sobolev spaces, and index theorem
Creators: name: Pilipović, Stevan
name: Prangoski, Bojan
name: Vindas, Jasson
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35S05, 47G30, 46E35, 35P20, 46F05

description: We study global regularity and spectral properties of power series of the Weyl quantisation $a^w$, where $a(x,ξ) $ is a classical elliptic Shubin polynomial. For a suitable entire function $P$, we associate two natural infinite order operators to $a^{w}$, $P(a^w)$ and $(P\circ a)^{w},$ and prove that these operators and their lower order perturbations are globally Gelfand-Shilov regular. They have spectra consisting of real isolated eigenvalues diverging to $\infty$ for which we find the asymptotic behaviour of their eigenvalue counting function. In the second part of the article, we introduce Shubin-Sobolev type spaces by means of $f$-$Γ^{*,\infty}_{A_p,ρ}$-elliptic symbols, where $f $ is a function of ultrapolynomial growth and $Γ^{*,\infty}_{A_p,ρ}$ is a class of symbols of infinite order studied in this and our previous papers. We study the regularity properties of these spaces, and show that the pseudo-differential operators under consideration are Fredholm operators on them. Their indices are independent on the order of the Shubin-Sobolev spaces; finally, we show that the index can be expressed via a Fedosov-Hörmander integral formula.
description: 36 pages. arXiv admin note: substantial text overlap with arXiv:1701.07907
Supplementary document for Super-resolved Raman imaging via galvo-painted structured line illumination - 6122741.pdf
Creators: name: Hu, Chuanzhen
name: Jiang, Ziling
name: Liu, Peng
name: YU, YAJUN
name: Chu, Kaiqin
name: Smith, Zachary
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Supplemental Material
Additional file 7: of X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells
Creators: name: Ho, Bianca
name: Greenlaw, Keelin
name: Tuwaijri, Abeer Al
name: Moussette, Sanny
name: Martínez, Francisco
name: Giorgio, Elisa
name: Brusco, Alfredo
name: Ferrero, Giovanni
name: Linhares, Natália
name: Eugênia Valadares
name: Svartman, Marta
name: Kalscheuer, Vera
name: Criado, Germán Rodríguez
name: Laprise, Catherine
name: Greenwood, Celia
name: Naumova, Anna
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Figure S3. Scatter plot of the first (PC1) and second (PC2) eigenvectors from a principal component analysis of methylation levels at 10 CpGs near the ZPBP2 transcriptional start site. The first principal component explains 59.2% of the variance in methylation levels. Points are colored by groups defined by presence of SRY and the number of X chromosomes. (DOCX 118 kb)
On two recent proposals for witnessing nonclassical gravity
Creators: name: Hall, Michael J. W.
name: Reginatto, Marcel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Two very similar proposals have been made recently for witnessing nonclassical features of gravity, by Bose et al. and by Marletto and Vedral. However, while these proposals are asserted to be very general, they are in fact based on a very strong claim: that quantum systems cannot become entangled via a classical intermediary. We point out that the support provided for this claim is only applicable to a very limited class of quantum-classical interaction models, corresponding to Koopman-type dynamics. We show that the claim is also valid for mean-field models, but that it is contradicted by explicit counterexamples based on the configuration-ensemble model. Thus, neither proposal provides a definitive test of nonclassical gravity.
description: New references added, minor corrections. Close to final version
Macrophages Phenotype Regulated by IL-6 Are Associated with the Prognosis of Platinum-Resistant Serous Ovarian Cancer: Integrated Analysis of Clinical Trial and Omics
Creators: name: Wu, Xiaoqing
name: Lu, Wenping
name: Xu, Chaojie
name: Jiang, Cuihong
name: Zhuo, Zhili
name: Wang, Ruipeng
name: Zhang, Dongni
name: Cui, Yongjia
name: Chang, Lei
name: Li, Chen
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Macrophages Phenotype
subject: IL-6
subject: Platinum-Resistant Serous Ovarian Cancer
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Background. The treatment of platinum-resistant recurrent ovarian cancer (PROC) is a clinical challenge and a hot topic. Tumor microenvironment (TME) as a key factor promoting ovarian cancer progression. Macrophage is a component of TME, and it has been reported that macrophage phenotype is related to the development of PROC. However, the mechanism underlying macrophage polarization and whether macrophage phenotype can be used as a prognostic indicator of PROC remains unclear. Methods. We used ESTIMATE to calculate the number of immune and stromal components in high-grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas database. The differential expression genes (DEGs) were analyzed via protein–protein interaction network, Kyoto Encyclopedia of Genes and Genomes (KEGG) and gene ontology (GO) analysis to reveal major pathways of DEGs. CD80 was selected for survival analysis. IL-6 was selected for gene set enrichment analysis (GSEA). A subsequent cohort study was performed to confirm the correlation of IL-6 expression with macrophage phenotype in peripheral blood and to explore the clinical utility of macrophage phenotype for the prognosis of PROC patients. Results. A total of 993 intersecting genes were identified as candidates for further survival analysis. Further analysis revealed that CD80 expression was positively correlated with the survival of HGSOC patients. The results of GO and KEGG analysis suggested that macrophage polarization could be regulated via chemokine pathway and cytokine–cytokine receptor interaction. GSEA showed that the genes were mainly enriched in IL-6-STAT-3. Correlation analysis for the proportion of tumor infiltration macrophages revealed that M2 was correlated with IL-6. The results of a cohort study demonstrated that the regulation of macrophage phenotype by IL-6 is bidirectional. The high M1% was a protective factor for progression-free survival. Conclusion. Thus, the macrophage phenotype is a prognostic indicator in PROC patients, possibly via a hyperactive IL-6-related pathway, providing an additional clue for the therapeutic intervention of PROC.
Additional file 6: of X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells
Creators: name: Ho, Bianca
name: Greenlaw, Keelin
name: Tuwaijri, Abeer Al
name: Moussette, Sanny
name: Martínez, Francisco
name: Giorgio, Elisa
name: Brusco, Alfredo
name: Ferrero, Giovanni
name: Linhares, Natália
name: Eugênia Valadares
name: Svartman, Marta
name: Kalscheuer, Vera
name: Criado, Germán Rodríguez
name: Laprise, Catherine
name: Greenwood, Celia
name: Naumova, Anna
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Table S4. Methylation percentages at the analyzed ZPBP2 DMR CGs from human non-transformed fibroblast cell lines, and the first PC of these values. (DOCX 14 kb)
Hawking radiation-quasinormal modes correspondence for large AdS black holes
Creators: name: Sun, Dao-Quan
name: Wang, Zi-Liang
name: He, Miao
name: Hu, Xian-Ru
name: Deng, Jian-Bo
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is well-known that the non-strictly thermal character of the Hawking radiation spectrum generates a natural correspondence between Hawking radiation and black hole quasinormal modes. This main issue has been analyzed in the framework of Schwarzschild black holes, Kerr black holes and nonextremal Reissner-Nordstrom black holes. In this paper, by introducing the effective temperature, we reanalysis the non-strictly thermal character of large AdS black holes. The results show that the effective mass corresponding to the effective temperature is approximatively the average one in any dimension. And the other effective quantities can also be obtained. Based on the known forms of frequency in quasinormal modes, we reanalysis the asymptotic frequencies of the large AdS black hole in three and five dimensions. Then we get the formulas of the Bekenstein-Hawking entropy and the horizon's area quantization with functions of the quantum "overtone" number $n$.
description: 6 pages
Toward Silicon-Matched Singlet Fission: Energy-Level Modifications Through Steric Twisting of Organic Semiconductors
Creators: name: Lee, Calvin J.
name: Sharma, Ashish
name: Panjwani, Naitik A.
name: Etchells, Isaac M.
name: Gholizadeh, Elham M.
name: White, Jonathan M.
name: Shaw, Paul E.
name: Burn, Paul. L.
name: Behrends, Jan
name: Rao, Akshay
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: diketopyrrolopyrroles
subject: organic semiconductors
subject: organic electronics
subject: photoenergy conversion
subject: singlet fission
subject: synthesis
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Singlet fission (SF) is a potential avenue for augmenting the performance of silicon photovoltaics, but the scarcity of SF materials energy-matched to silicon represents a barrier to the commercial realization of this technology. In this work, a molecular engineering approach is described to increase the energy of the S1 and T1 energy levels of diketopyrrolopyrrole derivatives such that the energy-level requirements for exothermic SF and energy-transfer to silicon are met. Time-resolved photoluminescence studies show that the silicon-matched materials are SF active in the solid state, forming a correlated triplet pair 1(TT) – a crucial intermediate in the SF process – as observed through Herzberg-Teller emission from 1(TT) at both 77 K and room temperature. Transient electron paramagnetic resonance studies show that the correlated triplet pair does not readily separate into the unbound triplets, which is a requirement for energy harvesting by silicon. The fact that the triplet pair do not separate into free triplets is attributed to the intermolecular crystal packing within the thin films. Nevertheless, these results demonstrate a promising route for energy-tuning silicon-matched SF materials.
Artefacts from the First and Second World Wars
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: The contributor explained that his grandfather, Francis "Frank" Kelland (1885-1969), had served in both the First and Second World Wars. Throughout the First World War, the contributor advised that Frank was an AB Seaman on HMS Conqueror, serving in the gunnery direction department of the battleship and surviving the main clash of fleets at Jutland in 1916. The contributor noted that, at the end of the war, HMS Conqueror and numerous other British ships were guarding the German High Seas Fleet which had been interned at Scapa Flow in Scotland.The contributor commented that the Germans had been forced under the terms of the 1918 Armistice to surrender their fleet, and in November 1918 they sailed across the North Sea to the Home Fleet base in Scotland. The contributor advised that the Germans had expected to be held for a short while and then released but, as the weeks turned into months, the German sailors who were being fed basic rations by the British were increasingly discontent. The contributor noted that they had fought for 5 years and now wished to return home as the war was over. The contributor shared that, in order to gain extra items like cigarettes and meat, the Germans bartered with their captors and this was likely how Frank had acquired the telescope. The contributor highlighted that, after seven months, the Germans became convinced that the British would seize the vessels for their own Navy and, on 21 June 1919, they scuttled their own fleet at Scapa Flow. The contributor added that the ships that carried the 15 cm SK L/45 that were interned at Scape Flow included the battleships Bayern, Derflinger, Hindenburg, Seydlitz, Grosser Kurfurst, Konig, Markgraf, and Kronprinz; as well as cruisers Brummer and Bremse. The contributor did not know from which ship the telescope was removed.The contributor shared about the items he had brought in, which had belonged to his grandfather. He noted that the spotting telescope was acquired from a battleship around 1914. The aircraft compass was from a PBY Catalina and was acquired by Frank during the Second World War. The contributor stated that the gas mask was issued from the mid 1930s by Pressed Steel Company and includes a section for spare lenses. When the gas mask was thrown away, its case could be used as a watertight container. The contributor described the book, "Forever England," as propaganda for children, which portrays the country in a very positive tone.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0245
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0245, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0245, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 5: of X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells
Creators: name: Ho, Bianca
name: Greenlaw, Keelin
name: Tuwaijri, Abeer Al
name: Moussette, Sanny
name: Martínez, Francisco
name: Giorgio, Elisa
name: Brusco, Alfredo
name: Ferrero, Giovanni
name: Linhares, Natália
name: Eugênia Valadares
name: Svartman, Marta
name: Kalscheuer, Vera
name: Criado, Germán Rodríguez
name: Laprise, Catherine
name: Greenwood, Celia
name: Naumova, Anna
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Developmental Biology
subject: Hematology

description: Figure S2. Sodium bisulfite sequencing methylation analysis of 51 CGs across the ZPBP2 promoter region shows higher methylation levels in fibroblast cell lines with two and three copies of the Xq arm. A: location of the 51 CGs interrogated using the sodium bisulfite sequencing assay shown in the context of the UCSC browser (hg19). B: heatmap representing mean methylation levels for each of the 51 CGs in cell lines with one X chromosome (two fibroblast cell lines with karyotype 45,X and no SRY region) and two or three copies of Xq (data from four fibroblast cell lines with karyotype 46,XX and two fibroblast cell lines from Turner syndrome patients with karyotype 46,i(Xq)). The black box beneath the heatmap shows the location of the 10 CGs analyzed by the pyrosequencing assay. The color scale for percent methylation is shown on the right. (DOCX 292 kb)
Optically levitated targets as a source for high brightness x-rays and a platform for mass-limited laser-interaction experiments
Creators: name: Giltrap, Samuel
Publisher: name: Imperial College London
Year: 2017

description: Targets on the scale of the wavelength of an irradiating laser have the potential to couple very strongly to ultra-short high-intensity laser fields through transient plasma resonances and Mie-like scattering processes, these targets are expected to absorb a significant fraction of the laser energy producing highly energetic x-rays and ions. Compared to bulk targets irradiated under similar conditions, mass-limited micro-targets are predicted to emit significantly higher x-ray photon energies as well as providing an enhancement to the ion acceleration fields. Optical levitation of microtargets enables a new class of experiments, with substantial modification of the charge up and neutralisation dynamics of a laser-plasma. Optically levitated targets (10micro-𝑚 droplets of silicon-based oil and ~100micro-𝑚 shells of silver coated glass) were characterised as both an x-ray and ion source. Experiments at low intensity (I ≅ 10E17Wcm−2) found a symmetric x-ray source in the 10 - 20micro-𝑚 size range, significantly smaller than comparable stalk mounted targets. This experiment also measured a two-temperature x-ray spectrum with electron temperatures of 0.6KeV and 2.3KeV. Experiments at the Vulcan facility RAL demonstrated levitated targets displayed a significantly increased front surface ion acceleration when compared to planar targets, with ions reaching energies of ~34M𝑒V whilst planar targets irradiated at a factor of 9 higher intensity produced ~12M𝑒V. The ion distribution from the droplet is found to have a weak preferential direction following the laser propagation axis, compared to planar targets which produce a tight beam emitted normal to the target surface. Several electromagnetic pulse (EMP) diagnostics were fielded; the levitated targets showed no EMP above the noise level of the detector (~40 V/m), stalk mounted targets showed significantly higher signal.
Memories of a Prisoner of War
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: The contributor spoke about the memoirs of her father, Dennis Ensor (born 5th August 1922), and some photographs from his life. Dennis joined the war effort before he was called up in December 1941 by joining the Air Raid Precautions (ARP) as a Warden. The contributor highlighted that his memoir retells one story of when he was demobbed in York, during which time he was working as a Wireless Operator. During the war, Dennis was held as a Prisoner of War at Stalag VII-A in southern Bavaria. The contributor brought a collection of letters from Sylvia, Dennis' wife, written while he was a Prisoner of War. Sylvia worked for the Auxiliary Fire Service during the war. Additionally, the contributor brought letters from the War Office stating that Dennis had gone missing on 31st August 1944, and later letters both speculating and, then, confirming that he was a prisoner of war at Stalag VII-A. The contributor highlighted one photograph she had brought of Dennis and Sylvia in 1946, 6 months after their marriage. Alongside the photographs, the contributor spoke about the additional objects she had brought: paybooks, ration books, identity books, and Dennis' Prisoner of War identity card. She noted that Dennis was awarded two medals for his service in the war: The War Medal (1939-1945) and the Star (1939-1945). Dennis served with the Royal Northfolk Regiment from 15th January 1942 until 12th September 1945 and, then, with the Royal Corps of Signals from 13th September 1945 until 6th January 1947. The contributor shared that Dennis had mentioned that he had seen a concentration camp but that he didn't talk about it. Finally, the contributor spoke about the items relating to her father in law, John Warwick, who was killed in action during Operation Torch.
Effective-field theory analysis of the $τ^- \to η^{(\prime)} π^- ν_τ$ decays
Creators: name: Garcés, E. A.
name: Villanueva, M. Hernández
name: Castro, G. López
name: Roig, P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The rare $τ^- \to η^{(\prime)} π^- ν_τ$ decays, which are suppressed by $G$-parity in the Standard Model (SM), can be sensitive to the effects of new interactions. We study the sensitivity of different observables of these decays in the framework of an effective field theory that includes the most general interactions between SM fields up to dimension six, assuming massless neutrinos. Owing to the strong suppression of the SM isospin breaking amplitudes, we find that the different observables would allow to set constraints on scalar interactions that are stronger than those coming from other low-energy observables.
description: 23 pages, 8 multiple figures and one table. Extended discussion of the hadronization of the tensor current and improved presentation of the plots. Accepted for publication in JHEP
How Can Research Projects Benefit from Standardized Metadata like DDI?
Creators: name: Perry, Anja
name: Watteler, Oliver
name: Zenk-Möltgen, Wolfgang
name: Gregory, Arofan
Publisher: name: Zenodo
Year: 2019
Subjects: data management
DDI
metadata
research projects

description: The DDI Standard is an open metadata standard for the Social Sciences and is mainly used by various data archives and larger research projects. The benefits of using standardized metadata and applying DDI are improved data documentation, automatic reports, interoperability, re-use of metadata, along with data comparison and harmonization.

 Very few small- and medium-sized research projects have adopted DDI so far. Challenges to adopt include high initial costs to implement DDI as part of new project management workflows, as well as the traditional working processes of researchers. A business case can be made for initial investments, as these will save costs in the long-term, but often these do not directly benefit the researchers. Adjustments in how research is conducted, however, can help researchers realize the benefits of standardized metadata during the course of a research project and afterwards. Such approaches could benefit from adjustments in the basic software tools researchers are accustomed to using.

 This paper aims to present straight forward ways and tools for these research projects to implement DDI and thus realize benefits from the start of a project. This paper examines the challenges faced by small- and medium-sized projects, and how DDI could be realistically used through the adjustment of working practices. It also identifies those areas where existing research software tools could be adjusted to better support metadata standards, and help to realize the benefits of their use.

 Thus, the paper addresses researchers and will reveal ways to make their research data management more efficient. It promotes DDI as an effective tool which can be applied by researchers in small- and medium-sized projects. Once accustomed to DDI, these researchers will have the skills and knowledge to use this standard in larger projects later in their careers, thereby contributing to the strength of the larger DDI community.
DNA methylation in lung cancer patients: Opening a "window of life" under precision medicine
Creators: name: Liang, Runzhang
name: Li, Xiaosong
name: Li, Weiquan
name: Zhu, Xiao
name: Li, Chen
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: DNA methylation
subject: Lung cancer
subject: Liquid biopsy
subject: Biomarker
subject: Treatment
subject: Prognosis
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in DNA sequence under the catalysis of DNA methyltransferase (DNMT) to produce 5-methyl cytosine. Some current studies have elucidated the mechanism of lung cancer occurrence and causes of lung cancer progression and metastasis from the perspective of DNA methylation. Moreover, many studies have shown that smoking can change the methylation status of some gene loci, leading to the occurrence of lung cancer, especially central lung cancer. This review mainly introduces the role of DNA methylation in the pathogenesis, early diagnosis and screening, progression and metastasis, treatment, and prognosis of lung cancer, as well as the latest progress. We point out that methylation markers, sample tests, and methylation detection limit the clinical application of DNA methylation. If the liquid biopsy is to become the main force in lung cancer diagnosis, it must make efficient use of limited samples and improve the sensitivity and specificity of the tests. In addition, we also put forward our views on the future development direction of DNA methylation.
Test one to test many: a unified approach to quantum benchmarks
Creators: name: Bai, Ge
name: Chiribella, Giulio
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum benchmarks are routinely used to validate the experimental demonstration of quantum information protocols. Many relevant protocols, however, involve an infinite set of input states, of which only a finite subset can be used to test the quality of the implementation. This is a problem, because the benchmark for the finitely many states used in the test can be higher than the original benchmark calculated for infinitely many states. This situation arises in the teleportation and storage of coherent states, for which the benchmark of 50% fidelity is commonly used in experiments, although finite sets of coherent states normally lead to higher benchmarks. Here we show that the average fidelity over all coherent states can be indirectly probed with a single setup, requiring only two-mode squeezing, a 50-50 beamsplitter, and homodyne detection. Our setup enables a rigorous experimental validation of quantum teleportation, storage, amplification, attenuation, and purification of noisy coherent states. More generally, we prove that every quantum benchmark can be tested by preparing a single entangled state and measuring a single observable.
description: 18 pages, 6 figures, fixed typos
Additional file 1 of The association of lipid ratios with hyperuricemia in a rural Chinese hypertensive population
Creators: name: Yu, Yu
name: Lan, Tian
name: Wang, Dandan
name: Fang, Wangsheng
name: Tao, Yu
name: Li, Minghui
name: Huang, Xiao
name: Zhou, Wei
name: Wang, Tao
name: Zhu, Lingjuan
name: Bao, Huihui
name: Cheng, Xiaoshu
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 1
The Mac Series of Educational Physiological Simulations
Creators: name: Bloch, Ralph
name: Ingram, David
name: Sweeney, George D.
name: Ahmed, Kursheed
Publisher: name: Zenodo
Year: 2024

description: The MAC-SERIES of four educational computer simulations was developed jointly between 1970 and 1985 in close cooperation by colleagues from the Faculty of Health Sciences (McMaster University) in Canada and the Medical College of St. Batholomew's Hospital (University of London) in the UK. This allowed medical students to experiment with the vital functions of the cardiovascular, pulmonary, and renal systems and how drugs are handled in the body without exposing live humans or animals to risks or discomfort. The four computer programs were MacDope, MacMan, MacPee, and MacPuf.
Effects of Planetesimal Accretion on the Thermal and Structural Evolution of Sub-Neptunes
Creators: name: Chatterjee, Sourav
name: Chen, Howard
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: A remarkable discovery of NASA's Kepler mission is the wide diversity in the average densities of planets of similar mass. After gas disk dissipation, fully formed planets could interact with nearby planetesimals from a remnant planetesimal disk. These interactions would often lead to planetesimal accretion due to the relatively high ratio between the planet size and the hill radius for typical planets. We present calculations using the open-source stellar evolution toolkit MESA (Modules for Experiments in Stellar Astrophysics) modified to include the deposition of planetesimals into the H/He envelopes of sub-Neptunes (~1-20 MEarth). We show that planetesimal accretion can alter the mass-radius isochrones for these planets. The same initial planet as a result of the same total accreted planetesimal mass can have up to ~5% difference in mean densities several Gyr after the last accretion due to inherent stochasticity of the accretion process. During the phase of rapid accretion these differences are more dramatic. The additional energy deposition from the accreted planetesimals increase the ratio between the planet's radius to that of the core during rapid accretion, which in turn leads to enhanced loss of atmospheric mass. As a result, the same initial planet can end up with very different envelope mass fractions. These differences manifest as differences in mean densities long after accretion stops. These effects are particularly important for planets initially less massive than ~10 MEarth and with envelope mass fraction less than ~10%, thought to be the most common type of planets discovered by Kepler.
description: 19 Pages, 10 Figures, 1 Table; Accepted for Publication in the Astrophysical Journal
Additional file 4: of X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells
Creators: name: Ho, Bianca
name: Greenlaw, Keelin
name: Tuwaijri, Abeer Al
name: Moussette, Sanny
name: Martínez, Francisco
name: Giorgio, Elisa
name: Brusco, Alfredo
name: Ferrero, Giovanni
name: Linhares, Natália
name: Eugênia Valadares
name: Svartman, Marta
name: Kalscheuer, Vera
name: Criado, Germán Rodríguez
name: Laprise, Catherine
name: Greenwood, Celia
name: Naumova, Anna
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Table S3. Fibroblast cell lines used for mapping of the X-linked modifier of methylation. (DOCX 14 kb)
Comentário ao acórdão do Tribunal da Relação de Lisboa de 17 de novembro de 1999 – contrato de trabalho de serviço doméstico; inexistência de subordinação jurídica
Creators: name: Júlio, Alda Maria Ferreira
Publisher: name: Direito e Justiça
Year: 2004

description: Direito e Justiça, v. 18 n. 1 (2004)
Spitfire or Hurricane Drop Tank
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: The contributor shared the story of how they obtained the spitfire dump tank. The contributor stated that, in approximately 1985, their in-laws spoke to a neighbour who mentioned "the bomb." Around 1999, "the bomb" was found and was identified as an aluminium drop tank. The contributor clarified that the drop tank was a long range tank for a Hurricane of Spitfire, which would be attached to the bottom of the plane. The contributor shared that the house where the drop tank was found is close to the Royal Air Force base in Abingdon. They explained that such tanks were found all over the area, particularly near to the River Thames. The contributor added that children used to strap these tanks together and use them for rafting. The contributor noted that the family had thought the tank was German; however, it was identified by the RAF as British. The contributor also stated that, during the war, soldiers had complained about the beer in France, so Watney's flew tanks over from England that were filled with their beer. The contributor noted that they keep this tank in their garden, and it is a good conversation starter.
A new abietane diterpene tuurgan a from caryopteris mongholica
Creators: name: Dai, Nayintai
name: Wang, Qinghu
name: Bai, Meirong
name: Yang, Liguo
name: Zhao, Yu
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: Virology

description: Five abietane diterpenes compounds were separated from petroleum ether extraction sites of ethanol extract of Caryopteris Mongholica, and Compound 1 was identified as a new abietane diterpenes compound by NMR and mass spectrometry, named as Tuurgan A of Caryopteris Mongholica; and Compounds 2-5 separated from Caryopteris Mongholica for the first time were identified as Ferruginol (2), Taxodione (3), Caryopterisoid Q (4), and Huperphlegmarin B (5). The anti-lung cancer activity of the Compounds 1-5 were determined, which results showed that they all had high A549 cytotoxicity.
Spectroscopic properties of luminous Lyman-α emitters at $z \approx 6 - 7$ and comparison to the Lyman-break population
Creators: name: Matthee, Jorryt
name: Sobral, David
name: Darvish, Behnam
name: Santos, Sérgio
name: Mobasher, Bahram
name: Paulino-Afonso, Ana
name: Röttgering, Huub
name: Alegre, Lara
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present spectroscopic follow-up of candidate luminous Ly$α$ emitters (LAEs) at $z=5.7-6.6$ in the SA22 field with VLT/X-SHOOTER. We confirm two new luminous LAEs at $z=5.676$ (SR6) and $z=6.532$ (VR7), and also present {\it HST} follow-up of both sources. These sources have luminosities L$_{\rm Lyα} \approx 3\times10^{43}$ erg s$^{-1}$, very high rest-frame equivalent widths of EW$_0\gtrsim 200$ Å and narrow Ly$α$ lines (200-340 km s$^{-1}$). VR7 is the most UV-luminous LAE at $z>6.5$, with M$_{1500} = -22.5$, even brighter in the UV than CR7. Besides Ly$α$, we do not detect any other rest-frame UV lines in the spectra of SR6 and VR7, and argue that rest-frame UV lines are easier to observe in bright galaxies with low Ly$α$ equivalent widths. We confirm that Ly$α$ line-widths increase with Ly$α$ luminosity at $z=5.7$, while there are indications that Ly$α$ lines of faint LAEs become broader at $z=6.6$, potentially due to reionisation. We find a large spread of up to 3 dex in UV luminosity for $>L^{\star}$ LAEs, but find that the Ly$α$ luminosity of the brightest LAEs is strongly related to UV luminosity at $z=6.6$. Under basic assumptions, we find that several LAEs at $z\approx6-7$ have Ly$α$ escape fractions $\gtrsim100$ \%, indicating bursty star-formation histories, alternative Ly$α$ production mechanisms, or dust attenuating Ly$α$ emission differently than UV emission. Finally, we present a method to compute $ξ_{ion}$, the production efficiency of ionising photons, and find that LAEs at $z\approx6-7$ have high values of log$_{10}(ξ_{ion}$/Hz erg$^{-1}) \approx 25.51\pm0.09$ that may alleviate the need for high Lyman-Continuum escape fractions required for reionisation.
description: 18 pages, 8 figures. Accepted for publication by MNRAS. Added new HST observations of VR7
Effects of tree shelterbelts on the hydrology of upland areas
Creators: name: Solloway, Imogen Abigail Sara
Publisher: name: Imperial College London
Year: 2012

description: Recent large flood events in the UK have focused attention on the effects of agricultural intensification and de-intensification on flood risk. Possible detrimental factors for these floods are thought to be the degradation of soil structure through compaction from grazing animals and agricultural machinery; while possible ameliorating factors may be the re-introduction of natural landscape features such as woodland and wetlands. In order to address this issue in an upland setting a multi-scale experimental programme has been implemented at Pontbren, a sheep-farmed headwater catchment of the River Severn, UK. The research aimed to evaluate the impact of different land management regimes on hydrological response. An integral component of this was to determine the role that native, broadleaf trees, planted as shelterbelts on intensively grazed pasture, may have in the reduction of flooding. Effects of trees on soil properties, soil moisture status, rainfall interception and overland flow were investigated Comparisons of soil hydraulic properties show significant increases in saturated moisture content and hydraulic conductivity of soil under trees compared to adjacent improved pasture. These effects, combined with increased interception and water use by the trees, have led to the soil under the trees being considerably drier than that under the pasture. The influence of the tree strips on rainfall patterns in the wider landscape is determined by the wind direction and inclination angle of the rain during rainfall events. The results show seasonal variation. Overland flow results show substantial differences in surface runoff between the grazed pasture and the ungrazed tree-planted area. Manipulation experiments reveal that, excluding sheep has a significant influence on surface hydrology at the plot scale, which is enhanced by planting trees. Data were used to underpin the conceptual understanding of the hydrological response, to support model development and thus make predictions under speculative land management scenarios.
FAIR Implementation Profiles (FIPs) and FAIR Enabling Resources (FERs) as accelerators of Interoperability and Reusability of Datasets across Multiple Communities.
Creators: name: Wyborn, Lesley
Publisher: name: Zenodo
Year: 2024
Subjects: Repositories
Identifiers
Infrastructure
Data
Vocabularies
Governance
Data Publishing

description: The Findable, Accessible, Interoperable, Reusable (FAIR) Guiding Principles of Wilkinson et al. (2016) put specific emphasis on using 'rich' metadata to enhance the ability of both humans and machines to find, access, aggregate and reuse data. Yet many datasets labelled as FAIR-compliant only meet Findable and Accessible and then only for humans. Few datasets are Interoperable and Reusable by machines mainly because there is insufficient specificity and granularity on the exact standards, formats and vocabularies implemented.

FAIR Implementation Profiles (FIPs) enable a  community  to declare the implementation choices it makes for each FAIR principle. Each choice is then published as a FAIR-Enabling Resource (FER), which is a machine-actionable nano-publication of any object (vocabularies, services, metadata profiles, etc) used to comply with a FAIR principle. FIPs, combined with FERs, can accelerate machine-actionable interoperability and reusability of datasets acquired by different communities, and at scale. FIPs can be visualised as knowledge graphs to help identify commonalities across communities, and provide more specificity than existing FAIR assessment methodologies.

The CODATA and RDA-led WorldFAIR Project on Global Cooperation on FAIR Data Policy and Practice (https://worldfair-project.eu/), funded by the European Commission WIDERA Programme, reviewed different approaches to FIPs from eleven disciplinary case studies: Chemistry, Nanomaterials, Geochemistry, Social Surveys, Population Health, Urban Health, Biodiversity, Agricultural Biodiversity, Oceans, Disaster Risk Reduction and Cultural Heritage. This paper will highlight how the Geochemistry case study created FIPS at multiple  community  levels (repository, data collection, dataset and reference) and will then compare and contrast with approaches of the other disciplines.
Additional file 3: of X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells
Creators: name: Ho, Bianca
name: Greenlaw, Keelin
name: Tuwaijri, Abeer Al
name: Moussette, Sanny
name: Martínez, Francisco
name: Giorgio, Elisa
name: Brusco, Alfredo
name: Ferrero, Giovanni
name: Linhares, Natália
name: Eugênia Valadares
name: Svartman, Marta
name: Kalscheuer, Vera
name: Criado, Germán Rodríguez
name: Laprise, Catherine
name: Greenwood, Celia
name: Naumova, Anna
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Computational Biology

description: Table S2. Fibroblast cell lines used for exploratory analysis. (DOCX 16 kb)
Blowup solutions for a reaction-diffusion system with exponential nonlinearities
Creators: name: Ghoul, Tej-Eddine
name: Nguyen, Van Tien
name: Zaag, Hatem
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We consider the following parabolic system whose nonlinearity has no gradient structure: $$\left\{\begin{array}{ll} \partial_t u = Δu + e^{pv}, \quad & \partial_t v = μΔv + e^{qu}, u(\cdot, 0) = u_0, \quad & v(\cdot, 0) = v_0, \end{array}\right. \quad p, q, μ> 0, $$ in the whole space $\mathbb{R}^N$. We show the existence of a stable blowup solution and obtain a complete description of its singularity formation. The construction relies on the reduction of the problem to a finite dimensional one and a topological argument based on the index theory to conclude. In particular, our analysis uses neither the maximum principle nor the classical methods based on energy-type estimates which are not supported in this system. The stability is a consequence of the existence proof through a geometrical interpretation of the quantities of blowup parameters whose dimension is equal to the dimension of the finite dimensional problem.
description: 47 pages. add references, many typos have been corrected. arXiv admin note: text overlap with arXiv:1610.09883
Memories of the Bacon Family
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: My brother, Allan Bacon, is on the board of directors for the Friends of The Canadian War Museum. He writes articles for them, and all the evidence provided relates to his time in Brighton during WWII. Currently 86 years old, he has lived in Canada for over 40 years.My brother lived in a small road in Brighton, No 62 Richmond Building, 2 up 2 down, with a toilet at the end of the garden. On Friday nights, it was bath night, and all six of us shared the same bath water.He attended Sussex St Infants' School in 1941 (at reception age 5). Every day, they had lessons where they had to wear gas masks, which they carried everywhere with them in small cardboard boxes. During air raids, he would go to the shelter under the playground.My father, Edward Charles Bacon, received his call-up papers during the war. He can remember that the street up the hill from where we lived was severely damaged, the brewery at the end of the street was hit, and the local cinema was badly damaged. During the raid, he sat on the sidewalk with a friend who was hurt. The raid was a 'hit and run raid' with no air raid siren.His earliest memory is from February 23rd, 1940, when my mother was making my birthday cake for the following day. The postman arrived to deliver my father's summons for military service. He remembers Mum bursting into tears and running to the place where Dad worked, a wholesale grocery warehouse. He reported for duty with the Royal Engineers on March 5th, 1940.He had 10 days of training with the army before leaving for France. Between May 27th and June 4th, he was evacuated from the beaches of Dunkirk. He was posted to the School of Military Engineering in Ripon, Yorkshire, where he taught a variety of skills, including bridging, demolitions, map reading, and later in the war, escape and evasion skills to RCAF bomber crews serving with Bomber Command 6 Group.As a Salvation Army family, we took turns hosting a German prisoner of war named Johann, who came for meals on Sundays with us. He had served with the Wehrmacht in Germany. One of the most treasured memories was having meals with him. My brother has a wooden tank made by Johann.They have left a much longer typed account of this, which they have left for us as an artefact. Copies of photographs have also been given to support this story.