cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Joint constraints on reionization: a framework for combining the global 21cm signal and the kinetic Sunyaev-Zel'dovich effect
Creators: name: Bégin, Joëlle-Marie
name: Liu, Adrian
name: Gorce, Adélie
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Recent measurements from the CMB and from high-redshift galaxy observations have placed rough constraints on the midpoint and duration of the Epoch of Reionization. Detailed measurements of the ionization history remain elusive, although two proposed probes show great promise for this purpose: the 21cm global signal and the kinetic Sunyaev-Zel'dovich (kSZ) effect. We formally confirm the common assumption that these two probes are highly complementary, with the kSZ being more sensitive to extended ionization histories and the global signal to rapidly evolving ones. We do so by performing a Karhunen-Loève (KL) transformation, which casts the data in a basis designed to emphasize the information content of each probe. We find that reconstructing the ionization history using both probes gives significantly more precise results than individual constraints, although carefully chosen, physically motivated priors play a crucial part in obtaining a bias-free reconstruction. Additionally, in the KL basis, measurements from one probe can be used to detect the presence of residual systematics in the other, providing a safeguard against systematics that would go undetected when data from each probe is analyzed in isolation. Once detected, the modes contaminated by systematics can be discarded from the data analysis to avoid biases in reconstruction.
description: 21 pages, 10 figures. Replaced to match the version accepted by PRD. Added to introduction and discussion, clarified some points. No qualitative changes to results. References updated
Romans 9:6-13 and John Piper's The Justification of God
Creators: name: Williams, Jonathan
Publisher: name: Zenodo
Year: 2020
Subjects: Election
Predestination
Calvinism
Arminianism
Paul
Apostle Paul
Theology of Paul
Covenants
Salvation of Israel
Romans 9
Epistle of Romans
John Piper
Sovereignty of God
Isaac and Ishmael
Jacob and Esau
children of promise
children of flesh

description: In Romans 9:1-5, the Apostle Paul records his sorrow and grief over the plight of his kinsmen. They are the covenant people of God. To them belongs the covenant promises and many other blessings. Yet they have failed to embrace the Messiah. How could this be? Paul explains this paradox beginning in 9:6-13. While some could say that God has not kept his promises, Paul adamantly promotes his view that God has been faithful to his word. He explains how he has been faithful to his covenant promises pulling illustrations from the history of his people to show how God has always worked. Thus, the lessons from the past explain his current situation. But Calvinists have seized upon Paul's explanation and found in them supposed proof for unconditional election to salvation. Is the Calvinist interpretation of Paul correct? Is Paul promoting unconditional election in 9:6-13? I think not. My paper exposes some of the fallacies in Calvinist thinking, exhibited pre-eminently in John Piper's scholarly work, "The Justification of God."
description: This paper is part of a requirement for a Ph.D. in Biblical Studies at Trinity Seminary. Because it deals only with Romans 9:6-13, and not the rest of Romans 9, the author recognizes that many issues will remain unaddressed. However, a previous paper has been uploaded dealing with 9:1-5 and a subsequent paper will deal with the rest of Romans 9 and the issues that arise from those verses. The author also welcomes interaction and can be contacted at jonathan@WGSministries.org.
Unified approach to cyclotron and plasmon resonances in a periodic 2DEG hosting the Hofstadter butterfly
Creators: name: Gudmundsson, Vidar
name: Mughnetsyan, Vram
name: Abdullah, Nzar Rauf
name: Tang, Chi-Shung
name: Moldoveanu, Valeriu
name: Manolescu, Andrei
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present theoretical calculations for the cyclotron resonance and various magnetoplasmon modes of a Coulomb interacting two-dimensional GaAs electron gas (2DEG) modulated as a lateral superlattice of quantum dots subjected to an external perpendicular constant magnetic field. We use a real-time excitation approach based on the Liouville-von Neumann equation for the density operator, that can go beyond linear response delivering information of all longitudinal and transverse collective modes of interest to the same order. We perform an extensive analysis of the coexisting collective modes due to the lateral confinement and the magnetic field for a different number of electrons in each dot. In the limit of vanishing dot modulation of the 2DEG we find signs of the structure of the Hofstadter butterfly in the excitation spectra.
description: RevTeX - pdfLaTeX, 10 pages with 9 pdf-figures included
Long-term viable bioaerosol sampling using a temperature- and humidity-controlled filtration apparatus, a laboratory investigation using culturable E. coli.
Creators: name: Walls, Howard J.
name: Kim, Jean H.
name: Yaga, Robert W.
name: Harvey, Lauren A.
name: Haines, Laura G.
name: Ensor, David S.
name: Hering, Susanne V.
name: Spielman, Steven R.
name: Kreisberg, Nathan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Sampling for culturable (e.g., viable) aerosolized microbes (bioaerosols) is a useful means to provide information for public health monitoring and studies. However, it is challenging to maintain microbe culturability when sampling at high flow rates (>12 L/min) and extended periods of time (≥4 h). We developed a first-generation, viable bioaerosol collection system (VBCS) utilizing temperature (T) and relative humidity (RH)–conditioned filtration at a flow rate of 25 L/min. A two-stage system of tube-in-shell Nafion™ exchange units provides cooling to ≤10°C and RH conditioning to 80–95%. Aerosol particles are collected on a polyurethane nanofiber filter providing a physical collection efficiency of >95% for sizes 0.06–10 µm. The T and RH conditions at the collection filter are maintained, despite changes to ambient conditions. The initial testing of the VBCS was done under indoor, laboratory conditions with aerosolized, vegetative E. coli. A scenario of a 30-min challenge of bioaerosol followed by continued sampling of clean air for various times was used to judge culturability maintenance under extended-term sampling. An initial loss of culturability upon collection onto the filter was observed; 23 ± 13% relative to 4-mm all-glass impinger. However once collected, 98% of culturability was maintained for an additional 4.5 h of sampling. An exponential decay in culturability was observed from 8 h to 15 h of sampling. Also, 24-h cold storage of the filters collected was studied. The VBCS is based on the use of dry filter cassettes, needs minimal maintenance, and preserves culturability of vegetative bacteria for >4 h. © 2017 RTI International and Aerosol Dynamics Inc.
Federated 3GPP Mobile Edge Computing Systems: A Transparent Proxy for Third Party Authentication with Application Mobility Support
Creators: name: Ali, Asad
name: Khan, Samin Rahman
name: Sakib, Sadman
name: Hossain, Md. Shohrab
name: Lin, Ying-Dar
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Multi-Access or Mobile Edge Computing (MEC) is being deployed by 4G/5G operators to provide computational services at lower latencies. Federating MECs across operators expands capability, capacity, and coverage but gives rise to two issues - third-party authentication and application mobility - for continuous service during roaming without re-authentication. In this work, we propose a Federated State transfer and 3rd-party Authentication (FS3A) mechanism that uses a transparent proxy to transfer the information of both authentication and application state across operators to resolve these issues. The FS3A proxy is kept transparent, with virtual counterparts, to avoid any changes to the existing MEC and cellular architectures. FS3A provides users with a token, when authenticated by an MEC, which can be reused across operators for faster authentication. Prefetching of subscription and state is also proposed to further reduce the authentication and application mobility latencies. We evaluated FS3A on an OpenAirInterface (OAI)-based testbed and the results show that token reuse and subscription prefetching reduce the authentication latency by 53-65%, compared to complete re-authentication, while state prefetching reduces application mobility latency by 51-91%, compared to no prefetching. Overall, FS3A reduces the service interruption time by 33%, compared to no token reuse and prefetching.
description: 14 pages. 8 figures. Submitted to IEEE Access
Additional file 1: of Carbon black suppresses the osteogenesis of mesenchymal stem cells: the role of mitochondria
Creators: name: Shen, Yulai
name: Wu, Lu
name: Qin, Dongdong
name: Xia, Yankai
name: Zhou, Zhu
name: Zhang, Xuemei
name: Wu, Xin
Publisher: name: figshare
Year: 2018
Subjects: Biochemistry
Medicine
Molecular Biology
Biological Sciences not elsewhere classified
Developmental Biology

description: Table S1. Primers used for real-time polymerase chain reaction (DOC 37Â kb)
Major Depressive Disorder – A Clinical Perspective: Concept, Treatment and the Place of Neurostimulation
Creators: name: Kosel, Markus Mathaus
Publisher: name: Université de Genève
Year: 2013
Subjects: info:eu-repo/classification/ddc/616.89
Major depression
Deep brain stimulation
Transcranial magnetic stimulation
Electroconvulsive therapy
Magnetic seizure therapy
Vagus nerve stimulation

description: Major depression is one of the most devastating disorders as measured by years of lives lost and diminished quality of live. According to treatment guidelines, mild depression should mainly be treated by psychotherapy, but moderate and severe disorders need very often pharmacological treatment. Drug therapy has several limitations: delay in treatment response, lack of efficacy, pharmacokinetic interactions, unwanted effects and unsatisfactory compliancy, especially in the long term treatment. About 30%-40% of moderate to severely depressed patients do not achieve remission after 2 antidepressant trials. They subsequently undergo treatment trials which are mainly based on the clinical practice of their prescriber. This is frequently a scientifically uninformed ‘‘trial and error'' approach. Indeed, solid evidence concerning individual therapeutic approaches is lacking. Electroconvulsive therapy is widely considered as an efficient treatment of last resort. But it is associated with cognitive side effects and high relapse rates. Its use is limited by availability and sometimes a negative perception by the public. Therefore, there is a need to develop alternative treatment approaches. Despite tremendous advances in genetics, neuroimagery, basic neurosciences and other research areas, depression is still considered as a “heterogeneous disorder with a highly variable course, an inconsistent response to treatment, and no established mechanism” (2). In this thesis, we discuss the concept, the clinical course and unmet needs in the treatment of major depression based on selective reviews. A particularly troublesome aspect, emergent suicidality during antidepressant treatment, is illustrated by own work. Electroconvulsive therapy as the paradigmatic, controversial somatic treatment of depression is described, besides newer techniques such as repetitive transcranial magnetic stimulation. We present also our own contributions in the field of neurostimulation, especially magnetic seizure therapy, vagus nerve stimulation and deep brain stimulation and discuss their place in the treatment armamentarium of depression. We outline ongoing research activity to treat severe depression by modulation of glutamatergic neurotransmission using ketamine in a translational approach. We hope to contribute through our studies to better treat and understand depression, one of the major challenges in the field of mental disorders.
Semiconductor-Dielectric-Metal Solar Absorbers with High Spectral Selectivity
Creators: name: Tervo, Eric J.
name: Steiner, Myles A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: An ideal solar thermal absorber has a sharp transition between high and low absorptance at the wavelength where the blackbody emissive power begins to exceed the solar irradiance. However, most real selective absorbers have a fairly broad transition, leading to both solar absorption and thermal emission losses. Here, we model, fabricate, and characterize a highly selective semiconductor-dielectric-metal (Ga0.46In0.54As - MgF2 - Ag) solar absorber with an extremely sharp transition from high to low absorptance. The thin semiconductor serves as a selective filter, absorbing photons with wavelengths shorter than the bandgap and transmitting those with longer wavelengths. The highly reflective dielectric-metal rear mirror allows the structure to have very low emittance for longer wavelengths. These characteristics provide the absorber with a measured solar absorptance >91% below the bandgap wavelength and infrared emittance <5% at 100 C above the bandgap wavelength. This transition wavelength can be tuned by modifying the semiconductor composition, and modeling indicates that the absorber's optical properties should be stable at high temperatures, making the structure a good candidate for unconcentrated to highly concentrated solar thermal energy conversion.
description: 16 pages, 6 figures
Call for establishing benchmark science and engineering
Creators: name: Zhan, Jianfeng
Publisher: name: arXiv
Year: 2021
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Currently, there is no consistent benchmarking across multi-disciplines. Even no previous work tries to relate different categories of benchmarks in multi-disciplines. This article investigates the origin and evolution of the benchmark term. Five categories of benchmarks are summarized, including measurement standards, standardized data sets with defined properties, representative workloads, representative data sets, and best practices, which widely exist in multi-disciplines. I believe there are two pressing challenges in growing this discipline: establishing consistent benchmarking across multi-disciplines and developing meta-benchmark to measure the benchmarks themselves. I propose establishing benchmark science and engineering; one of the primary goals is to set up a standard benchmark hierarchy across multi-disciplines. It is the right time to launch a multi-disciplinary benchmark, standard, and evaluation journal, TBench, to communicate the state-of-the-art and state-of-the-practice of benchmark science and engineering.
Evaluation of hemodynamics in cerebral aneurysms: novel approaches using computational flow dynamics (CFD) and digital subtracted angiography
Creators: name: Mendes Pereira, Vitor
Publisher: name: Université de Genève
Year: 2013
Subjects: info:eu-repo/classification/ddc/616.0757
Computational flow dynamics
Intracranial aneurysms
Stenting
Angiography
Transcranial doppler
Hemodynamics

description: The evaluation of cerebral hemodynamics has been a challenge for researchers and medical professionals, particularly in the study of intracranial aneurysms. In contrast to high-quality anatomical imaging, hemodynamic and functional assessments are immature and imprecise. We are describing a series of experimental and clinical studies focusing on the assessment of the intracranial hemodynamics in a context of IAs using different modalities like: computational flow dynamics, transcranial Doppler and digital subtracted angiography. We report form the most experimental assessment and the technical challenges that it could present to the latest clinical application of the flow assessment in clinical patients. The translational link between the experimental to the clinical work is clear and necessary because in both ways validation is required and necessary. We present different experiments and studies on the domains of fluids and vascular science to determine the results and propose recommendations to facilitate a better understanding of the subject.
Principles of Superiority, Equivalence and Non-inferiority trials
Creators: name: Panuwat Pensawangwat
Publisher: name: Faculty of Pharmaceutical Sciences KKU, MSU, UBU
Year: 2020
Subjects: superiority, equivalence, non-inferiority, statistical significance, clinical significance

description: Isan Journal ofPharmaceutical Sciences, 16, 1, 16-25
Test particle energization of heavy ions in magnetohydrodynamic turbulence
Creators: name: Pugliese, Facundo
name: Dmitruk, Pablo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In the present work, we study the energization and displacement of heavy ions through the use of test particles interacting with the electromagnetic fields of magnetohydrodynamic (MHD) turbulence. These fields are obtained from pseudospectral direct numerical solutions (DNSs) of the compressible three-dimensional MHD equations with a strong background magnetic field. We find particle energization to be predominantly perpendicular as the ions become heavier (lower charge-to-mass ratio) and that high displacement is detrimental for perpendicular energization. On the other hand, perpendicular displacement is unaffected by the charge-to-mass ratio, which we explain with a simple guide center model. Using Voronoi tessellation along with this model, we analyze preferential concentration and find that particles behave as tracers in the perpendicular plane, clustering in regions with $\nabla_\perp\cdot\mathbf{u}_\perp < 0$. These regions also have $(\nabla\times\mathbf{E})_z < 0$, which is optimal for perpendicular energization, thus providing a mechanism to understand precedent results.
CORE: A Knowledge Graph Entity Type Prediction Method via Complex Space Regression and Embedding
Creators: name: Ge, Xiou
name: Wang, Yun-Cheng
name: Wang, Bin
name: Kuo, C. -C. Jay
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: Entity type prediction is an important problem in knowledge graph (KG) research. A new KG entity type prediction method, named CORE (COmplex space Regression and Embedding), is proposed in this work. The proposed CORE method leverages the expressive power of two complex space embedding models; namely, RotatE and ComplEx models. It embeds entities and types in two different complex spaces using either RotatE or ComplEx. Then, we derive a complex regression model to link these two spaces. Finally, a mechanism to optimize embedding and regression parameters jointly is introduced. Experiments show that CORE outperforms benchmarking methods on representative KG entity type inference datasets. Strengths and weaknesses of various entity type prediction methods are analyzed.
Histological and Immunohistochemical Investigations of Acute Right Ventricular Damage in Forensic Pathology
Creators: name: Fracasso, Tony
Publisher: name: Université de Genève
Year: 2013
Subjects: info:eu-repo/classification/ddc/614.1
Right ventricle
Autopsy pathology
Forensic pathology
Heart ischemia
Pulmonary hypertention
Acute damage

description: The right ventricle has been considered for a long time as a mere passive chamber without relevant function. This misconception has led to the consequence that scientists concentrated their attention on the study of the left ventricle and that pathology and physiopathology of the right one have been relatively neglected. This is particularly evident in the medicolegal literature, in which specific studies miss, though a role of the right ventricle in the determination of death has been proposed in different causes of death. The leading thread of this work was the investigation of the pathology of the right ventricle in a series of different causes of death typically observed in forensic pathology, in which an acute stress of the right ventricular myocardium could be assumed. The investigated groups were: fatal pulmonary embolism, pulmonary fat embolism, carbon monoxide intoxications, ethanol intoxications and traumatic brain injuries. Besides conventional histology, we performed immunohistochemical investigations with the antibodies against fibronectin and the terminal complement complex C5b-9 on human cardiac autopsy samples from both ventricles. In the investigated groups fresh ischemic damage prevalently localized at the right ventricle was detected. Data from the literature suggest that acute persistent pulmonary hypertension can be the main factor determining right ventricular damage and failure in these groups.
Training Needs and Abilities in the Implementation of Consumer Protection Relating to Health Products at the District Level of Thailand
Creators: name: Jareeluck Hinsui
Publisher: name: Faculty of Pharmaceutical Sciences KKU, MSU, UBU
Year: 2020
Subjects: Competent Officials, Improvement of Skill, District Level, Competency, Public Health Executives

description: Isan Journal ofPharmaceutical Sciences, 16, 1, 26-36
ANA CLAUDIA FARRANHA.pdf
Creators: name: Farranha, Ana Claudia
Publisher: name: figshare
Year: 2017
Subjects: subject: Law
subject: FOS: Law

description: This article seeks to show some results about the Research “Public Administration and Social and Digital Networks”. The main questions about the research were: what the meaning of the presence of Public Administration in the Social and Digital Networks? It is possible to ask about the use that Brazilian Government do on Facebook? This use is good for more participation in the politics? For have some answers about these questions, we have done 04 interviews with communication managers of these institutions: The Ministry of Agrarian Development (MDA), the Ministry of Planning and Budget (MPOG) and the Special Secretariat for Racial Equality Policies (SEPPIR) and the Comptroller General of the Union (CGU). For methodology, we use the content analysis. This method supports to identify some elements that are presents in the government view about the social and digital networks. In the end, we try to offer some answers the question of research. We try to analyze some challenges to more politics participation in the actuality and how these issues can have some dialogs with Law and Politics.
title: Re-building untold histories to preserve historical fragments along the street Rua do Benformoso in Lisbon
Creators: name: Stellacci, Stefania
Publisher: name: Conference Proceedings XXIX International Seminar on Urban Form ISUF 2022 Urban Redevelopment and Revitalisation A Multidisciplinary Perspective/Lodz University of Technology Press
Year: 2023
Subjects: Community awareness, historical data, Lisbon, overhanging dwellings, spatial urban form.

description: Unbalanced tourist flows combined with aggressive lending and real estate markets can threaten the preservation of the built heritage, its sensitive and adaptive reuse. The sustainable management of endangered (or underrepresented) buildings is particularly critical in overcrowded historic centres, such as Lisbon.
This research focuses on the spatial configuration of the street Rua do Benformoso in a traditional parish of Lisbon, where the building blocks remained unscathed after the 1755 earthquake. In revealing permanence, dissonance, and change of individual plots (or part of plots), this study draws attention on one of those physical features that characterized this street, the overhanging timber-frame constructions.
The importance of interpreting the changes of the street-blocks by combing different records and bringing urban morphology, history, architecture and engineering is emphasized. In future studies, distinct morphological periods can be analysed considering map-based information and archival photos. Keeping alive irreplaceable physical legacies (or historical fragments) can contribute to sustainable heritage management of popular tourist cities, like Lisbon.
Although this graspable memory is partial, it can represent a vehicle for a closer relationship to the past and for connecting urban morphology to heritage conservation practice.
Long-term viable bioaerosol sampling using a temperature- and humidity-controlled filtration apparatus, a laboratory investigation using culturable E. coli.
Creators: name: Walls, Howard J.
name: Kim, Jean H.
name: Yaga, Robert W.
name: Harvey, Lauren A.
name: Haines, Laura G.
name: Ensor, David S.
name: Hering, Susanne V.
name: Spielman, Steven R.
name: Kreisberg, Nathan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Sampling for culturable (e.g. viable) aerosolized microbes (bioaerosols) is a useful means to provide information for public health monitoring and studies. However, it is challenging to maintain microbe culturability when sampling at high flow rates (>12 L/min) and extended periods of time (≥4 hours). We developed a first-generation, viable bioaerosol collection system (VBCS) utilizing temperature (T) and relative humidity (RH)–conditioned filtration at a flow rate of 25 L/min. A two-stage system of tube-in-shell Nafion™ exchange units provides cooling to ≤10°C and RH conditioning to 80–95%. Aerosol particles are collected on a polyurethane nanofiber filter providing a physical collection efficiency of >95% for sizes 0.06–10 µm. The T and RH conditions at the collection filter are maintained, despite changes to ambient conditions. The initial testing of the VBCS was done under indoor, laboratory conditions with aerosolized, vegetative E. coli. A scenario of a 30-minute challenge of bioaerosol followed by continued sampling of clean air for various times was used to judge culturability maintenance under extended-term sampling. An initial, loss of culturability upon collection onto the filter was observed; 23±13% relative to 4-mm all-glass impinger. However once collected, 98% of culturability was maintained for an additional 4.5 hours of sampling. An exponential decay in culturability was observed from 8 hours to 15 hours of sampling. Also, 24-hour cold storage of the filters collected was studied. The VBCS is based on the use of dry filter cassettes, needs minimal maintenance, and preserves culturability of vegetative bacteria for >4 hours.
Development of Risk Score Model for Hospital-acquired Acute Kidney Injury in a Tertiary Care Hospital in Thailand
Creators: name: Nutcharin Lueangingkhasut
Publisher: name: Faculty of Pharmaceutical Sciences KKU, MSU, UBU
Year: 2020
Subjects: Hospital-Acquired Acute Kidney Injury, Risk Score Model

description: Isan Journal ofPharmaceutical Sciences, 16, 1, 37-48
Multi-photon multi-quantum transitions in the spin-3/2 silicon-vacancy centers of SiC
Creators: name: Singh, Harpreet
name: Hollberg, Mario Alex
name: Anisimov, Andrei N.
name: Baranov, Pavel G.
name: Suter, Dieter
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Silicon vacancy centers in silicon carbide are promising candidates for storing and manipulating quantum information. Implementation of fast quantum gates is an essential requirement for quantum information processing. In a low magnetic field, the resonance frequencies of silicon vacancy spins are in the range of a few MHz, the same order of magnitude as the Rabi frequencies of typical control fields. As a consequence, the rotating wave approximation becomes invalid and nonlinear processes like the absorption and emission of multiple photons become relevant. This work focuses on multi-photon transitions of negatively charged silicon vacancies driven by a strong RF field. We present continuous-wave optically detected magnetic resonance (ODMR) spectra measured at different RF powers to identify the 1-, 2-, and 3-RF photon transitions of different types of the silicon vacancy in the 6$H$-SIC polytype. Time-resolved experiments of Rabi oscillations and free induction decays of these multiple RF photon transitions were observed for the first time. Apart from zero-field data, we also present spectra in magnetic fields with different strength and orientation with respect to the system's symmetry axis.
Spreading of a droplet impacting on a smooth flat surface: how liquid viscosity influences the maximum spreading time and spreading ratio
Creators: name: Aksoy, Yunus Tansu
name: Eneren, Pinar
name: Koos, Erin
name: Vetrano, Maria Rosaria
Publisher: name: arXiv
Year: 2021
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Existing energy balance models, which estimate maximum droplet spreading, insufficiently capture the droplet spreading from low to high Weber and Reynolds numbers and contact angles. This is mainly due to the simplified definition of the viscous dissipation term and incomplete modeling of the maximum spreading time. In this particular research, droplet impact on a smooth sapphire surface is studied for seven glycerol concentrations between 0% - 100%, and 294 data points are acquired using high-speed photography. Fluid properties such as density, surface tension, and viscosity are also measured. For the first time according to the authors' knowledge, we incorporate the fluid viscosity in the modeling of the maximum spreading time based on the recorded data. We also estimate the characteristic velocity of the viscous dissipation term in the energy balance equation. These viscosity-based characteristic scales help to formulate a more comprehensive maximum droplet spreading model. Thanks to this improvement, our model successfully fits the data available in the literature for various fluids and surfaces compared to the existing models.
Consecutive level spacings in the chiral Gaussian unitary ensemble: From the hard and soft edge to the bulk
Creators: name: Akemann, G.
name: Gorski, V.
name: Kieburg, M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The local spectral statistics of random matrices forms distinct universality classes, strongly depending on the position in the spectrum. Surprisingly, the spacing between consecutive eigenvalues at the spectral edges has received little attention, where the density diverges or vanishes, respectively. This different behaviour is called hard or soft edge. We show that the spacings at the edges are almost indistinguishable from the spacing in the bulk of the spectrum. We present analytical results for consecutive spacings between the $k$th and $(k+1)$st smallest eigenvalues in the chiral Gaussian unitary ensemble, both for finite- and large-$n$. The result depends on the number of the generic zero modes $ν$ and the number of flavours $N_{\rm f}$, which are given in terms of characteristic polynomials, as motivated by Quantum Chromodynamics (QCD). We find that the convergence in $n$ is very rapid. The same can be said separately about the limit $k\to\infty$ (limit to the bulk) and $ν\to\infty$ (limit to the soft edge). Interestingly, the Wigner surmise is a very good approximation for all these cases and, apart from $k=1$, shows a deviation below one percent. These findings are corroborated with Monte-Carlo simulations. We finally compare for $k=1$ with data from QCD on the lattice, being in this symmetry class.
description: 25 pages, 8 figures; v2: typos corrected and references added, accepted in J. Phys. A special issue to honour Fritz Haake
In Vitro Antioxidant and Cytoprotective Activities of Extracts from Four Solanum Fruits
Creators: name: Pannarat Akanitapichat
Publisher: name: Faculty of Pharmaceutical Sciences KKU, MSU, UBU
Year: 2020
Subjects: Solanum, antioxidant, cytoprotective

description: Isan Journal ofPharmaceutical Sciences, 16, 1, 49-58
Spontaneous Radiation of Black Holes
Creators: name: Zeng, Ding-fang
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We provide an explicitly hermitian hamiltonian description for the spontaneous radiation of black holes, which is a many-level, multiple-degeneracy generalization of the usual Janeys-Cummings model for two-level atoms. By standard Wigner-Wiesskopf approximation, we show that for the first one or few particles' radiation our model yields completely the same power spectrum as hawking radiation requires. While in the many-particle radiation cases, numeric methods allow us to follow the evolution of microscopic state of a black hole exactly, from which we can get the firstly increasing then decreasing entropy variation trend for the radiation particles just as the Page-curve exhibited. Basing on this model analysis, we claim that two ingredients are necessary for resolutions of the information missing puzzle, a spontaneous radiation like mechanism for the production of hawking particles and proper account of the macroscopic superposition happening in the full quantum description of a black hole radiation evolution and, the working logic of replica wormholes is an effect account of this latter ingredient. As the basis for our interpretation of black hole Hawking radiation as their spontaneous radiation, we also provide a fully atomic like inner structure models for their microscopic states definition and origins of their Bekenstein-Hawking entropy, that is, exact solution families to the Einstein equation sourced by matter constituents oscillating across the central point and their quantization. Such a first quantization model for black holes' microscopic state is non necessary for our spontaneous radiation description, but has advantages comparing with other alternatives, such as string theory fuzzball or brick wall models.
description: references rearranging, some expressions refining. Version to appear in Nucl.Phys.B
Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes
Creators: name: Kissing, Sandra
name: Rudnik, Sönke
name: Damme, Markus
name: Lüllmann-Rauch, Renate
name: Atsuhiro Ichihara
name: Kornak, Uwe
name: Eeva-Liisa Eskelinen
name: Jabs, Sabrina
name: Heeren, Jörg
name: Brabander, Jef K. De
name: Haas, Albert
name: Saftig, Paul
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine

description: The vacuolar-type H+-translocating ATPase (v-H+-ATPase) has been implicated in the amino acid-dependent activation of the mechanistic target of rapamycin complex 1 (MTORC1), an important regulator of macroautophagy. To reveal the mechanistic links between the v-H+-ATPase and MTORC1, we destablilized v-H+-ATPase complexes in mouse liver cells by induced deletion of the essential chaperone ATP6AP2. ATP6AP2-mutants are characterized by massive accumulation of endocytic and autophagic vacuoles in hepatocytes. This cellular phenotype was not caused by a block in endocytic maturation or an impaired acidification. However, the degradation of LC3-II in the knockout hepatocytes appeared to be reduced. When v-H+-ATPase levels were decreased, we observed lysosome association of MTOR and normal signaling of MTORC1 despite an increase in autophagic marker proteins. To better understand why MTORC1 can be active when v-H+-ATPase is depleted, the activation of MTORC1 was analyzed in ATP6AP2-deficient fibroblasts. In these cells, very little amino acid-elicited activation of MTORC1 was observed. In contrast, insulin did induce MTORC1 activation, which still required intracellular amino acid stores. These results suggest that in vivo the regulation of macroautophagy depends not only on v-H+-ATPase-mediated regulation of MTORC1.
MOESM1 of Overexpression of a type III PKS gene affording novel violapyrones with enhanced anti-influenza A virus activity
Creators: name: Hou, Lukuan
name: Huang, Huiming
name: Li, Huayue
name: Wang, Shuyao
name: Ju, Jianhua
name: Li, Wenli
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health

description: Additional file 1: Table S1. Plasmids and strains used in this study. Table S2. Primer pairs used in this study. Table S3. Homologous locus of vioAB in different Streptomyces genomes. Figure S1. Relative yields for compounds 1â 14 in different strains. Figure S2. Spectral data of 1. Figure S3. Spectral data of 2. Figure S4. Spectral data of 3. Figure S5. Spectral data of 4. Figure S6. Spectral data of 5. Figure S7. Spectral data of 6. Figure S8. Spectral data of 7. Figure S9. Spectral data of 8. Figure S10. Spectral data of 9. Figure S11. Spectral data of 10. Figure S12. Spectral data of 11. Figure S13. Spectral data of 12. Figure S14. Spectral data of 13. Figure S15. Spectral data of 14. Figure S16. Multiple-sequence alignments of VioA with selected type III PKSs. Figure S17. Site-directed mutagenesis study of VioA.
Combining randomized field experiments with observational satellite data to assess the benefits of crop rotations on yields
Creators: name: Kluger, Dan M.
name: Owen, Art B.
name: Lobell, David B.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences
subject: 62P12, 62D20

description: With climate change threatening agricultural productivity and global food demand increasing, it is important to better understand which farm management practices will maximize crop yields in various climatic conditions. To assess the effectiveness of agricultural practices, researchers often turn to randomized field experiments, which are reliable for identifying causal effects but are often limited in scope and therefore lack external validity. Recently, researchers have also leveraged large observational datasets from satellites and other sources, which can lead to conclusions biased by confounding variables or systematic measurement errors. Because experimental and observational datasets have complementary strengths, in this paper we propose a method that uses a combination of experimental and observational data in the same analysis. As a case study, we focus on the causal effect of crop rotation on corn (maize) and soy yields in the Midwestern United States. We find that, in terms of root mean squared error, our hybrid method performs 13% better than using experimental data alone and 26% better than using the observational data alone in the task of predicting the effect of rotation on corn yield at held-out experimental sites. Further, the causal estimates based on our method suggest that benefits of crop rotations on corn yield are lower in years and locations with high temperatures whereas the benefits of crop rotations on soy yield are higher in years and locations with high temperatures. In particular, we estimated that the benefit of rotation on corn yields (and soy yields) was 0.84 t/ha (0.23 t/ha) on average for the top quintile of temperatures, 1.02 t/ha (0.20 t/ha) on average for the whole dataset, and 1.18 t/ha (0.15 t/ha) on average for the bottom quintile of temperatures.
Biochemical analysis of force-sensitive responses using a large-scale cell stretch device
Creators: name: Renner, Derrick J.
name: Ewald, Makena L.
name: Kim, Timothy
name: Yamada, Soichiro
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: Physical force has emerged as a key regulator of tissue homeostasis, and plays an important role in embryogenesis, tissue regeneration, and disease progression. Currently, the details of protein interactions under elevated physical stress are largely missing, therefore, preventing the fundamental, molecular understanding of mechano-transduction. This is in part due to the difficulty isolating large quantities of cell lysates exposed to force-bearing conditions for biochemical analysis. We designed a simple, easy-to-fabricate, large-scale cell stretch device for the analysis of force-sensitive cell responses. Using proximal biotinylation (BioID) analysis or phospho-specific antibodies, we detected force-sensitive biochemical changes in cells exposed to prolonged cyclic substrate stretch. For example, using promiscuous biotin ligase BirA* tagged α-catenin, the biotinylation of myosin IIA increased with stretch, suggesting the close proximity of myosin IIA to α-catenin under a force bearing condition. Furthermore, using phospho-specific antibodies, Akt phosphorylation was reduced upon stretch while Src phosphorylation was unchanged. Interestingly, phosphorylation of GSK3β, a downstream effector of Akt pathway, was also reduced with stretch, while the phosphorylation of other Akt effectors was unchanged. These data suggest that the Akt-GSK3β pathway is force-sensitive. This simple cell stretch device enables biochemical analysis of force-sensitive responses and has potential to uncover molecules underlying mechano-transduction.
Additional file 1: of Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1
Creators: name: Liu, Liang
name: Ruiz, Jimmy
name: OâNeill, Stacey
name: Grant, Stefan
name: Petty, W.
name: Yang, Meng
name: Chen, Kexin
name: Topaloglu, Umit
name: Pasche, Boris
name: Zhang, Wei
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Methods and Materials. (DOCX 30Â kb)
Clinical Aspects of Olfactory and Gustatory Disorders
Creators: name: Landis, Basile Nicolas
Publisher: name: Université de Genève
Year: 2011
Subjects: info:eu-repo/classification/ddc/616.8
Olfaction
Gustation

description: Olfaction and taste are two well known human senses. Everybody would agree that both senses are crucial in daily activities such as eating or drinking. Olfactory and gustatory information is important for our quality of life. How should we otherwise enjoy an excellent wine or taste our favorite dish? On the other hand, both senses represent an alarm system providing us with information about spoiled food or leaking gas. It is undeniable that olfactory information influences our behavior, but to what extent olfactory and taste stimuli influence our interaction with other humans and biological processes, is still a matter of debate within the field. Which importance an intact olfactory and gustatory function have, becomes often clear when theses senses are affected. The following thesis reflects the authors own clinical experience and publications as well as the thoughts, concepts, state of the art knowledge and research questions shared with national and international colleagues working in the same field of chemosensory disorders. The thesis draws a general overview of current concepts in human smell and taste disorders.
Outcomes and prioritization
Creators: name: Rhon, Dan
name: Young, Jodi L.
name: Junkin, Jennifer
name: Vraa, Derek
Publisher: name: OSF Registries
Year: 2023

description: The primary outcome of this study is to assess the transparency of the reporting of clinical trials for manual therapy in patients with low back pain. Information will be collected about the registration and then will be compared to the report in the study publication.
Folding molecular dynamics simulation of T-peptide, a HIV viral entry inhibitor : Structure, dynamics, and comparison with the experimental data
Creators: name: Gkogka, Ioanna
name: Glykos, Nicholas M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Biomolecules (q-bio.BM)
subject: FOS: Biological sciences

description: Peptide T is a synthetic octapeptide fragment, which corresponds to the region 185-192 of the gp120 HIV coat protein and functions as a viral entry inhibitor. In this work, a folding molecular dynamics simulation of peptide T in a membrane-mimicking (DMSO) solution was performed with the aim of characterizing the peptide's structural and dynamical properties. We show that peptide T is highly flexible and dynamic. The main structural characteristics observed were rapidly interconverting short helical stretches and turns, with a notable preference for the formation of $β$-turns. The simulation also indicated that the C-terminal part appears to be more stable than the rest of the peptide, with the most preferred conformation for residues 5-8 being a $β$-turn. In order to validate the accuracy of the simulations, we compared our results with the experimental NMR data obtained for the T-peptide in the same solvent. In agreement with the simulation, the NMR data indicated the presence of a preferred structure in solution that was consistent with a $β$-turn comprising the four C-terminal residues. An additional comparison between the experimental and simulation-derived chemical shifts also showed a reasonable agreement between experiment and simulation, further validating the simulation-derived structural characterization of the T-peptide.