cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany
Creators: name: Auzanneau, Marie
name: Eckert, Alexander J.
name: Meyhöfer, Sebastian M.
name: Heni, Martin
name: Gillessen, Anton
name: Schwettmann, Lars
name: Jehle, Peter M.
name: Hummel, Michael
name: Holl, Reinhard W.
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Type 1 diabetes
subject: adults
subject: diabetes technology
subject: CGM
subject: pump
subject: age
subject: gender
subject: deprivation
subject: DDC 610 / Medicine & health

description: Introduction: Diabetes technology improves glycemic control and quality of life for many people with type 1 diabetes (T1D). However, inequalities in access to diabetes technology exist in many countries. In Germany, disparities in technology use have been described in pediatric T1D, but no data for adults are available so far. We therefore aimed to analyze whether demographic factors and area deprivation are associated with technology use in a representative population of adults with T1D. Materials and methods: In adults with T1D from the German prospective diabetes follow-up registry (DPV), we analyzed the use of continuous subcutaneous insulin infusion (CSII), continuous glucose monitoring (CGM), and sensor augmented pump therapy (SAP, with and without automated insulin delivery) in 2019-2021 by age group, gender, migration background, and area deprivation using multiple adjusted regression models. Area deprivation, defined as a relative lack of area-based resources, was measured by quintiles of the German index of Multiple Deprivation (GIMD 2015, from Q1, least deprived, to Q5, most deprived districts). Results: Among 13,351 adults with T1D, the use of technology decreased significantly with older age: CSII use fell from 56.1% in the 18−<25-year age group to 3.1% in the ≥80-year age group, CGM use from 75.3% to 28.2%, and SAP use from 45.1% to 1.5% (all p for trend <0.001). The use of technology was also significantly higher in women than in men (CSII: 39.2% vs. 27.6%; CGM: 61.9% vs. 58.0%; SAP: 28.7% vs. 19.6%, all p <0.001), and in individuals without migration background than in those with migration background (CSII: 38.8% vs. 27.6%; CGM: 71.1% vs. 61.4%; SAP: 30.5% vs. 21.3%, all p <0.001). Associations with area deprivation were not linear: the use of each technology decreased only from Q2 to Q4. Discussion: Our real-world data provide evidence that higher age, male gender, and migration background are currently associated with lower use of diabetes technology in adults with T1D in Germany. Associations with area deprivation are more complex, probably due to correlations with other factors, like the higher proportion of migrants in less deprived areas or the federal structure of the German health care system.
School of Advanced Professional Studies - Jahresbericht 2014
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: Weiterbildende Masterstudiengänge
subject: Wissenschaftliche Weiterbildung
subject: Berufsbegleitendes Studium
subject: Zertifikatskurs
subject: Blended Learning
subject: E-Learning
subject: Sensorsystemtechnik
subject: Innovations- und Wissenschaftsmanagement
subject: Aktuarwissenschaften
subject: Aufstieg durch Bildung: offene Hochschulen
subject: SAPS
subject: School of Advanced Professional Studies
subject: DDC 050 / General serial publications
subject: DDC 370 / Education
subject: Continuing education
subject: Universities; Germany; Ulm
subject: Kontaktstudium
subject: Universität Ulm

description: Die SAPS konnte sich als Zentrum für berufsbegleitende universitäre Weiterbildung im Jahr 2014 bundesweit positionieren: die Universität Ulm schickt sich an, ab 2015 eines von drei Regionalzentren des bundesweiten Netzwerks der »Offenen Hochschulen« zu werden. Seit Gründung der SAPS wurde ein umfangreiches Methodenarsenal in der Online-Lehre aufgebaut und anhand zweier Pilotstudiengänge evaluiert. Die ersten beiden weiterbildenden Studiengänge »Innovations- und Wissenschaftsmanagement« und »Sensorsystemtechnik« nahmen ihren Betrieb auf. In einem neuen Fördervorhaben »Effizient Interaktiv Studieren – EffIS«, beantragt in der zweiten Förderrunde von »Aufstieg durch Bildung: offene Hochschulen«, erhielt die Universität Ulm den Zuschlag. Im Projekt wird u.a. untersucht, ob technisch anspruchsvolle Methoden wie z. B. Online-Simulationen in der Weiterbildung tatsächlich zu einem besseren Lernerfolg führen. Im Rahmen des vom MWK geförderten Vorhabens "NOW:Master" wird ein dritter berufsbegleitender Studiengang »Aktuarwissenschaften« aufgebaut.
Open Life Science - Training and Mentoring programme - Website release 2019-2021
Creators: name: Batut, Bérénice
name: Yehudi, Yo
name: Sharan, Malvika
name: Tsang, Emmy
name: Community, Open Life Science
Publisher: name: Forschungzentrum Jülich
Year: 2021
Subjects: Website, Jekyll, GitPage

description: doi:10.5281/ZENODO.5636584
description: The Open Life Science (OLS) program helps individuals and stakeholders in research to become Open Science ambassadors . About This is a 16-week long personal mentorship and cohort-based training , where participants (organisers, hosts, mentors and project leads/mentees) of this program will: share their expertise and gain knowledge essential to create, lead, and sustain an Open Science project connect with members across different projects, communities, backgrounds, and identities empower each other to become effective Open Science ambassadors in their communities
Timing of young radio pulsars - I. Timing noise, periodic modulation, and proper motion
Creators: name: Parthasarathy, A.
name: Shannon, Ryan
name: Johnston, S.
name: Lentati, L.
name: Bailes, Matthew
name: Dai, S.
name: Kerr, M.
name: Manchester, R. N.
name: Oslowski, Stefan
name: Sobey, C.
name: van Straten, Willem
name: Weltevrede, P.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 5101
subject: Astronomical sciences
classificationCode: 5109
subject: Space sciences

description: The smooth spin-down of young pulsars is perturbed by two non-deterministic phenomenon, glitches, and timing noise. Although the timing noise provides insights into nuclear and plasma physics at extreme densities, it acts as a barrier to high-precision pulsar timing experiments. An improved methodology based on the Bayesian inference is developed to simultaneously model the stochastic and deterministic parameters for a sample of 85 high-(E) over dot radio pulsars observed for similar to 10 yr with the 64-m Parkes radio telescope. Timing noise is known to be a red process and we develop a parametrization based on the red-noise amplitude ((Ared)) and spectral index (beta). We measure the median Ared to be -10.4(-1.7)(+1.8) yr(3/2) and ss to be -5.2(-3.8)(+3.0) and show that the strength of timing noise scales proportionally to nu(1)vertical bar(nu) over dot vertical bar(-0.6 +/- 0.1), where. is the spin frequency of the pulsar and.. is its spin-down rate. Finally, we measure significant braking indices for 19 pulsars and proper motions for 2 pulsars, and discuss the presence of periodic modulation in the arrival times of 5 pulsars.
L'originaire et l'activité de représentation : exposé critique de la théorie métapsychologique de Piera Aulagnier et comparaison avec la théorie cartésienne de la connaissance.
Creators: name: Dubois-Flynn, Geneviève.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Philosophy.

description: Cette these se propose d'etudier la theorie metapsychologique de P. Aulagnier sur "l'originaire". L'originaire serait l'un des trois espaces psychiques que P. Aulagnier postule pour rendre compte du fonctionnement psychique au niveau de l'infans. L'activite principale que P. Aulagnier lui associe est une activite de representation, qui donne lieu a des representations pictographiques. Mais, forclos au pouvoir de connaissance du Je, seuls les effets de l'originaire produits sur le Je peuvent etre percus et ce, dans des moments de vecu psychotique. Nous nous proposons d'abord de faire l'expose des theories de l'originaire et de la representation de l'auteure, pour en decouvrir ensuite les points forts et les insuffisances. Nous ramenerons ensuite la discussion sur un plan plus philosophique en comparant la theorie de la connaissance de P. Aulagnier avec la theorie cartesienne de la connaissance, autour du problene de la relation ame-corps, et autour du probleme de la representation. Nous verrons ainsi, bien que de facon sommaire, comment ces deux domaines du savoir peuvent etre source d'un eclairage mutuel. (Abstract shortened by UMI.)
Stratégie argumentative dans le discours des banques : la position du sujet.
Creators: name: Fauvel, Sébastien R.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Language, Rhetoric and Composition.

description: Cette thèse pose un regard nouveau sur un discours méconnu qui pourtant, joue un rôle d'influence important dans notre vie quotidienne: celui des banques. À l'aide des théories de l'énonciation, on arrive à dégager de ce discours qui se dit objectif des marques explicites et surtout, implicites, de subjectivité. Par l'analyse des choix lexicaux et des figures présentes dans ces textes, il devient possible de circonscrire un ensemble de valeurs constitutives de l'image et du rôle social que s'attribuent ces puissantes sociétés. Par un ensemble d'exemples tirés des textes entourant le débat sur les projets de fusions bancaires au Canada en 1998, nous arrivons à poser l'hypothèse que le discours des banques se caractérise par sa visée: imposer l'image d'une industrie solide qui se veut au service et à l'écoute des besoins de sa clientèle tout en étant une industrie responsable dont l'ensemble des activités sert les intérêts de tous les citoyens.
Setting paradise on fire: Men, women and the politics of devotion in the Grand siecle.
Creators: name: Legault, Lise.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Religion, History of.

description: This is a study of the politics of devotion in the Grand siecle . It concentrates on the activities of a small group of devout Catholics in Paris, who from the beginning to the end of the century exercised an influence on public life out of proportion to their numbers. This group came to be known to historians as the parti devot . The men and women of the parti devot were celebrated both for their profound spirituality and their political activism in the Catholic cause. Devot women were visible everywhere, teaching the young, healing the sick and proselytizing their families. They were so much at the centre of French devotional life that at times they appeared to steal the initiative from men. Yet many in the Church continued to fear their influence, and to regard them as dangerously vulnerable to heresy. How, then, were they able to rise above their limitations and take a central place in the devotional life of the period? The answer lies in the political position of devot clerics. France in the seventeenth century was a nation haunted by fear of religious war and external attack. As a result, Catholic clergy were under scrutiny as they had seldom been before, forced to choose between God and Caesar. Their divided loyalties rendered them less effective as reformers. It was against this background that women came to be so important to the reform of French Catholicism. Devot clerics encouraged women to do what they could not do, say what they could not say, knowing that women were not taken seriously as either theologians or political leaders. Thus women were valuable to the Church precisely because they were marginal in society. They, in turn, were able to exploit the situation for their own benefit, discovering a world of devotion and religious activism which had previously been closed to them.
APM2 is a novel mediator of cisplatin resistance in a variety of cancer cell types in vitro and in xenograft models of cancer
Creators: name: Scott, Bradley James
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Health Sciences, Pharmacology.

description: Resistance to traditional modes of cancer therapy is a major obstacle facing cancer patients. The untreated HCT116 cell line was subcloned and each clone was assessed for its response to several drugs and X-radiation. One clone HCT116-K was resistant to cisplatin/etoposide/topotecan but sensitive to XR while another HCT116-2 was sensitive to cisplatin but resistant to XR. HCT116-10, a clone that responded to drugs and radiation in a manner similar to parental HCT116 cells was used as a control clone. Comparing gene expression between HCT116-K, or HCT116-2, vs. HCT116-10, we were able to identify several genes whose expressions were altered in clones that were resistant/sensitive to various insults. Each identified gene's expression was then examined in a panel of HCT116 clones to determine whether the expression observed in the resistant/sensitive clone was outside the normal expression distribution within the population. One gene APM2 was significantly upregulated in HCT116-K. Upon follow-up, APM2, was found to promote cisplatin resistance when overexpressed in sensitive HCT116 clones. Furthermore, silencing APM2, using sequence specific siRNAs, in a panel of cell lines encompassing all combinations of p53 status and MMR proficiency (HCT116-K, HCT116, SW620, MCF7, PC-3, and OV2008) resulted in sensitization regardless of these two factors. In addition, silencing APM2 stably, using shRNAs, also resulted in the sensitization of cells to cisplatin. More importantly, cisplatin inhibited the growth of APM2 silenced tumour xenografts (HCT116-K or OV2008 cells) significantly better than it inhibited the growth of xenografts carrying non-targeting control shRNAs. Additionally, APM2 was found to be localized to the cytoplasm and membrane. Further investigation revealed that HCT1 16 cells secrete APM2 to the extracellular space representing a possible mechanism by which APM2 promotes cellular resistance to cisplatin, by binding to and carrying cisplatin out of the cell. These findings represent a novel strategy that could be exploited to overcome cisplatin resistance in patients regardless of p53 status or ability to perform MMR.
Modelling future mortality in Ontario: Extension of the PREVENT model and development of an Ontario database.
Creators: name: Herbert, Margaret Elizabeth.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Health Sciences, Public Health.

description: PREVENT is a user-friendly, interactive computer program developed in the Netherlands which integrates the effects of demographic structure, risk factor prevalence, relative risks and mortality rates to estimate the impact of changes in risk factor prevalence on mortality. A new database for PREVENT has been developed with the following Ontario data: population structure, all-cause and disease-specific mortality, life expectancy, and birth projections. The current prevalence of smoking, obesity, alcohol and seat belt use is estimated from the Ontario Health Survey; the prevalence of hypertension and hypercholesterolemia from provincial heart health surveys. Future changes in risk factor prevalences for the simulation period are extrapolated from past trends. Sensitivity testing shows that the mortality varies directly with both the prevalence and relative risks. The shape of the mortality prevention curve is affected by two factors. In the first twenty years the latency and lag times and the spread in implementation of the intervention dictate the pattern. In later years mortality is affected by the changing demographic structure, age-specific mortality rates and future trends in risk factor prevalence that are in the model. Historical testing of the risk factor smoking, using a 1966 Ontario database, shows good agreement between PREVENT estimates and observed total mortality. The agreement between predicted and observed mortality is not as close for lung cancer, IHD and COLD.
Seismic performance of tall buildings designed following non-prescriptive design procedures
Creators: name: Kakoty, Preetish
name: Monfared, Alireza Eksir
name: Molina Hutt, Carlos
Publisher: name: The University of British Columbia
Year: 2020

description: Currently enforced building code requirements for earthquakes, including the guidelines for seismic design of tall buildings using non-prescriptive design procedures, are primarily intended to minimize life-safety risks due to structural damage under extreme earthquakes. While tall buildings designed under current standards are expected to achieve such life-safety goal, this study estimates their performance could require recovery times on the order of 3 to 9 months to repair damage from a designlevel earthquake (roughly equivalent to ground motion shaking with a 10% chance of exceedance in 50 years). This study evaluates how recovery-based design guidelines may address these extensive downtime risks by enforcing: (i) tighter drift limits under expected ground motions; (ii) enhanced design criteria for critical nonstructural components; and (iii) measures to mitigate externalities that impede recovery. To illustrate these findings, a 42-story residential reinforced concrete shear wall building in San Francisco, CA is used as a case study. This paper is a summary of Part 3 of San Francisco’s Tall Buildings Study, a recently completed Applied Technology Council Project for the City and County of San Francisco, in which the authors participated.
"Led by the spirit of humanity": Canadian military nursing, 1914-1929.
Creators: name: Newell, Margaret Leslie.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1996
Subjects: subject: History, Canadian.

description: This study examines Canadian military nursing from the onset of the 1914 Great War to the end of the first post-War decade in 1929. Its purpose is to focus on the experience of military nursing in an attempt to discover the specifics of the profession, particularly during the interwar years, and to analyse the factors that affected military nursing during that era. The analysis of military nursing in context with the era revealed three main conclusions. First, unlike the peacetime experience, military nursing during the Great War was a professionally and culturally liberating experience that set Military Nurses apart form their civil peers. Unfortunately, during the interwar years, the re-instatement of Nursing Sisters to pre-War military positions of administration, removed them from the clinical setting, was deleterious to the profession, and did not accord them the opportunity to apply the practice element of their profession. Second, the introduction of non-commissioned men as hospital orderlies provided the major hospital military workforce that maintained the Nursing Sister's distance from the bedside and usurped them of their clinical focus and the opportunity to provide patient care. As an unfavourable offshoot to this, Military Nurses were restricted to administration. Without a practice component to their profession, Military Nurses had little in common with their civil peers who were actively engaged in practice and in activities to advance the profession. Last, the limitation imposed upon Nursing Sisters' by their appointment of relative rank precluded them from advancing within the military organization, from participating in the re-structuring of the CAMC and from influencing any policy that affected patient services or the Nursing profession. (Abstract shortened by UMI.)
Heterologous rhamnolipid biosynthesis: advantages, challenges, and the opportunity to produce tailor-made rhamnolipids
Creators: name: Wittgens, Andreas
name: Rosenau, Frank
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: rhamnolipids
subject: Burkholderia glumae
subject: heterologous production
subject: quorum sensing
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Biosurfactants
subject: Surface-active agents
subject: Microbiological phenomena
subject: Pseudomonas aeruginosa
subject: Biotechnology; Methods
subject: Drug discovery
subject: Biotensid
subject: Rhamnolipide
subject: Pseudomonas putida

description: The first heterologous expression of genes responsible for the production of rhamnolipids was already implemented in the mid-1990s during the functional identification of the rhlAB operon. This was the starting shot for multiple approaches to establish the rhamnolipid biosynthesis in different host organisms. Since most of the native rhamnolipid producing organisms are human or plant pathogens, the intention for these ventures was the establishment of non-pathogenic organisms as heterologous host for the production of rhamnolipids. The pathogenicity of producing organisms is one of the bottlenecks for applications of rhamnolipids in many industrial products especially foods and cosmetics. The further advantage of heterologous rhamnolipid production is the circumvention of the complex regulatory network, which regulates the rhamnolipid biosynthesis in wild type production strains. Furthermore, a suitable host with an optimal genetic background to provide sufficient amounts of educts allows the production of tailor-made rhamnolipids each with its specific physico-chemical properties depending on the contained numbers of rhamnose sugar residues and the numbers, chain length and saturation degree of 3-hydroxyfatty acids. The heterologous expression of rhl genes can also enable the utilization of unusual carbon sources for the production of rhamnolipids depending on the host organism.
Corticotropin-releasing hormone (CRH) alters mitochondrial morphology and function by activating the NF-kB-DRP1 axis in hippocampal neurons
Creators: name: Battaglia, Chiara R.
name: Cursano, Silvia
name: Calzia, Enrico
name: Catanese, Alberto
name: Böckers, Tobias M.
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Mechanisms of disease
subject: Stress and resilience
subject: S-NITROSYLATION
subject: NITRIC-OXIDE
subject: COMPLEX-I
subject: CRISTAE
subject: DYNAMICS
subject: DDC 610 / Medicine & health
subject: Neurodegenerative diseases
subject: Alzheimer disease
subject: Gene expression
subject: NF-kappa B
subject: Brain
subject: Proteins
subject: Alzheimerkrankheit
subject: Genexpression
subject: Nuklearfaktor Kappa B

description: Abstract Neuronal stress-adaptation combines multiple molecular responses. We have previously reported that thorax trauma induces a transient loss of hippocampal excitatory synapses mediated by the local release of the stress-related hormone corticotropin-releasing hormone (CRH). Since a physiological synaptic activity relies also on mitochondrial functionality, we investigated the direct involvement of mitochondria in the (mal)-adaptive changes induced by the activation of neuronal CRH receptors 1 (CRHR1). We observed, in vivo and in vitro, a significant shift of mitochondrial dynamics towards fission, which correlated with increased swollen mitochondria and aberrant cristae. These morphological changes, which are associated with increased NF-kB activity and nitric oxide concentrations, correlated with a pronounced reduction of mitochondrial activity. However, ATP availability was unaltered, suggesting that neurons maintain a physiological energy metabolism to preserve them from apoptosis under CRH exposure. Our findings demonstrate that stress-induced CRHR1 activation leads to strong, but reversible, modifications of mitochondrial dynamics and morphology. These alterations are accompanied by bioenergetic defects and the reduction of neuronal activity, which are linked to increased intracellular oxidative stress, and to the activation of the NF-kB/c-Abl/DRP1 axis.
There's nothing routine about depression
Creators: name: Tumarkin, Maria
Publisher: name: Swinburne
Year: 2024

description: A recent study from the World Health Organisation has identified depression as the world's most debilitating illness. It is debilitating for the millions of individual sufferers, for the fabric of our societies and, of course, for the economy. Increasingly, the question of depression is demanding serious political engagement from any self-respecting (and suitably astute) government.
Cognitive bias modification for interpretation (CBM-I) for post-traumatic stress disorder: study protocol of an app-based randomised controlled trial
Creators: name: Kroener, Julia
name: Greiner, Alexander
name: Sosic-Vasic, Zrinka
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Clinical trials
subject: Adult psychiatry
subject: Anxiety disorders
subject: DDC 610 / Medicine & health

description: IntroductionPrevious studies indicate that computerised trainings implementing cognitive bias modification (CBM) for interpretation bias might be promising treatments for trauma-related cognitive distortions and symptoms. However, results are mixed, which might be related to the implemented task (sentence completion task), setting, or training duration. Within the present study, we aim to evaluate the efficacy and safety of an app-based intervention for interpretation bias using standardised imagery audio scripts, which is designed as a standalone treatment.Methods and analysisThe study is a randomised controlled trial, implementing two parallel arms. 130 patients diagnosed with post-traumatic stress disorder (PTSD) will be allocated to either the intervention group or the waiting-list control group receiving treatment as usual. The intervention consists of 3 weeks of an app-based CBM training for interpretation bias using mental imagery, with three training sessions (20 min) per week. Two months after the last training session, 1 week of booster CBM treatment will be implemented, consisting of three additional training sessions. Outcome assessments will be conducted pretraining, 1 week post-training, 2 months post-training, as well as 1 week after the booster session (approximately 2.5 months after initial training termination). The primary outcome is interpretation bias. Secondary outcomes include PTSD-related cognitive distortions and symptom severity, as well as negative affectivity. Outcome assessment will be conducted by intention-to-treat analysis, as well as per-protocol analysis using linear mixed models.Ethics and disseminationThe study was approved by the Ethics Committee of the State Chamber of Physicians in Baden-Wuerttemberg, Germany (number of approval: F-2022-080). Scientific findings will be published in peer-reviewed journals informing future clinical studies, which focus on the reduction of PTSD-related symptoms using CBM.Trial registration numberGerman Clinical Trials Register (DRKS00030285; https://drks.de/search/de/trial/DRKS00030285).
'Don't measure profits, go for the goals': preliminary investigation into how owner-operator objectives impact perceived SME performance
Creators: name: Newby, Rick
name: Watson, John
Publisher: name: Swinburne
Year: 2024

description: By examining their relative usefulness in explaining the utility owners receive from their firms, this study finds that both 'objective' economic return and 'subjective' owner-operator goal achievement play a significant role. However, 'objective' economic return was found to be less effective than its 'subjective' alternative, thereby debunking the argument that income/wealth maximization is the only, or even the best, way to assess a SME owner's utility. The findings also support the contention that measures of SME performance should incorporate how effectively firms in achieving their owner-operators' goals.
Principes humanistes des lumières et problématique fondationnelle des droits de l'homme.
Creators: name: Sosoé, Varus Atadi.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Philosophy.

description: Ma these porte sur les droits de l'homme en tant que droits naturels, ante- et supra-positifs en prenant appui sur le principe de conservation de soi, base du positivisme juridique hobbesien. Elle defend la perspective du jusnaturalisme kantiano-rousseauiste via la reconstruction de leurs theories de l'etat de nature, et retient resolument le principe, qui leur est consubstantiel, de l'humanite, le principe de la dignite intangible de l'homme comme arche des arche, comme Idee des Idees regulatrices ethiques et juridico-politiques. Au-dela de la liberte egale pour tous et de la rationalite, qui sont generalement tenus pour les fondements des droits de l'homme par les critiques du droit et de l'Etat modernes, j'ai pose ce principe comme principe limitatif. C'est une conception qui obeit a cette pensee kantienne selon laquelle ce qui limite doit-etre necessairement different et superieur a ce qu'il sert a limiter, ce qui me semble rigoureusement fidele a l'esprit et a la lettre des Declarations des droits de l'homme de 1789, en passant par celui de 1946, jusqu' a nos jours. Partant de cette conception, je critique les perspectives contemporaines, en l'occurence, la perspective de la fondation communicationnelle de Habermas et celle, sceptique, anti-rationaliste de Kai Nielsen qui repose sur la methode dite de l'Equilibre Reflechi Large (ERL). Ainsi, ma these comporte ces trois moments importants: critique du positivisme juridique, critique de l'application de la theorie habermasienne au droit, et critique du scepticisme anti-fondationnaliste de Kai Nielsen, sans oublier, pour plus de precision, le second grand moment et le plus important, puisque c'est la tradition que j'ai defendue, mon interpretation et ma defense de la doctrine du droit naturel, en l'occurence moderne. En l'occurence, puisque j'ai essaye de relever les points de raccordement essentiels qui subsistent indeniablement entre cette doctrine et celle de l'Antiquite. (Abstract shortened by UMI.)
Unmapped Water Access: Locating the Role of Religion in Access to Municipal Water Supply in Ahmedabad
Creators: name: Mawani, Vrushti
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Poor access to municipal water in Ahmedabad’s Muslim areas has been tied to the difficulties of implementing a planning mechanism called the town planning scheme, which, in turn, have been premised on widespread illegal constructions that have developed across these sites. Residents, local politicians, and activists associate this causal explanation offered by engineers and planners for poor water access with a deliberate state-led intent to discriminate against them on the basis of religion. Using this causal association as a methodological entry-point, I examine through this paper how religious difference mediates decision-making and outcomes embodied by technical plans. Demonstrating how the uneven implementation of plans is not always a state-driven exercise as is often imagined, but instead a culmination of intense mediations between influential state and non-state actors with varying interests, I offer the following insights on water governance for sites divided by religion: (a) Negotiations driven by discourses on religious difference are a powerful force influencing the formulation of plans facilitating water access. However, these negotiations and plans are, simultaneously, also vulnerable to other political, legal, and economic pressures. Water governance across such sites thus often unfolds in an unstable landscape of unmapping and mapping; (b) influential legal actors from both majority and minority communities exert pressures obstructing the formulation and implementation of technical plans. The production of observable unmapped water access in minority areas thus, in reality, might not be contained within neat divides such as religion or illegality, but instead be a culmination of shifting interests, contestations, and negotiations confounding such categories; (c) institutionalized planning practices implicated in the intentional production of unmapping in such contexts might instead simply be discursive categories around which uneven water access coalesces.
EFFICIENT USE OF AGRICULTURAL LAND IN BANGLADESH: STRATEGIES FOR OPTIMIZATION
Creators: name: Yeasmin, Homayora
name: Sanawar, Saifa Binte
name: Sharmin, Shaila
name: Islam, Mohammad Amirul
name: Yeasmin, Homayora
name: Sanawar, Saifa Binte
name: Sharmin, Shaila
name: Islam, Mohammad Amirul
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Optimization
subject: agricultural land
subject: Bangladesh

description: Bangladesh is an agrarian country trying to feed an increasing population with gradually diminishing cultivable land. Majority of the population in Bangladesh depends directly or indirectly on agriculture. The agriculture of Bangladesh is capable of producing different types of crops all around the year. However, crop-wise nutritional value is different from crop to crop. As the amount of cultivable land is a major issue for crop cultivation, required domestic production is very much dependent on the optimum use of these lands. Every year, Bangladesh is to import and export various agricultural products to respond to additional demand and surplus production. The presence of strategies to maintain optimum use of land for each crop based on the domestic demand and export-import policies would stabilize the production system in Bangladesh. Cost of production and fair farm gate price of agricultural produce are two most important aspects related to the smooth marketing of the agricultural products, which also have significant impact on the production of a certain crop in successive years. As there is no alternative technique other than placing pressure on the scarce arable land of Bangladesh to ensure food security for its 168.96 million people, only a better planning for agricultural lands by expected crops may help solve the problem. The main objective of this research is to optimize the amount of land for each type of crop, especially for the rabi season, in order to maximize the farm-gate price and minimize the cost of production to help policy makers for devising better policy to ensure food security of the country. With the help of sophisticated statistical techniques this research suggests some alternative scenarios of optimum use of arable land by crops in rabi season that will enable the government to device appropriate strategies and incentive plans.
Implementing consumer health research: empirical results leading to social innovation in New Zealand
Creators: name: Boyd, Mary-Anne
name: Nel, Pieter
name: Hansen, Jens
Publisher: name: Swinburne
Year: 2024

description: Health research is sometimes regarded as fragmented, competitive and highly specialized activity in which groups of researchers within scientific disciplines often work in isolation from other disciplines. Methodological approaches and the value placed on them differ across academic disciplines and their associated professions (Riehl & Roy, 1974; Zemke & Clark, 1996) and across cultures (de Rivero, 2003). Such factors adversely impact teamwork competency within health service organisations, and contribute to the fragmentation of health service experience for consumers. Importantly, there is often little effective communication and consultation between the producers of health research and the end users (Pang et al., 2003 p815). Greater involvement of laypeople in database management teams was recommended following a review of 105 clinical databases in UK (Black, Barker, & Payne, 2004), and an Australian review came to a similar conclusion (Daly, McDonald, & Willis, 1992). Involving consumers in the whole process of research from selection of topics through to report writing is a largely unexplored area. There is considerable scope for collaborative approaches with well-networked consumers, promoting skill and resource development, and creating contexts within which to develop and follow appropriate research practices (Oliver et al., 2004; Waterman, Tillen, Dickson, & Koning, 2001). The contention is that real world science can help inform decisions by stakeholders (Amador & Fitzpatrick, 2003). Consumer perspectives are basic to the design and local development of primary health care and innovative service integration, yet consumer research is underdeveloped in New Zealand.
A High Time-resolution Study of the Millisecond Pulsar J2241-5236 at Frequencies below 300 MHz
Creators: name: Kaur, D.
name: Bhat, N. D.R.
name: Tremblay, S. E.
name: Shannon, Ryan
name: McSweeney, S. J.
name: Ord, S. M.
name: Beardsley, A. P.
name: Crosse, B.
name: Emrich, D.
name: Franzen, T. M.O.
name: Horsley, L.
name: Johnston-Hollitt, M.
name: Kaplan, D. L.
name: Kenney, D.
name: Morales, M. F.
name: Pallot, D.
name: Steele, K.
name: Tingay, S. J.
name: Trott, C. M.
name: Walker, M.
name: Wayth, R. B.
name: Williams, A.
name: Wu, C.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 5101
subject: Astronomical sciences
classificationCode: 5109
subject: Space sciences

description: One of the major challenges for pulsar timing array (PTA) experiments is the mitigation of the effects of the turbulent interstellar medium (ISM) from timing data. These can potentially lead to measurable delays and/or distortions in the pulse profiles and scale strongly with the inverse of the radio frequency. Low-frequency observations are therefore highly appealing for characterizing them. However, in order to achieve the necessary time resolution to resolve profile features of short-period millisecond pulsars, phase-coherent dedispersion is essential, especially at frequencies below 300 MHz. We present the lowest-frequency (80-220 MHz), coherently dedispersed detections of one of the most promising pulsars for current and future PTAs, PSR J2241-5236, using our new beamformer software for the MWA's voltage capture system, which reconstructs the time series at a much higher time resolution of similar to 1 mu s by resynthesizing the recorded voltage data at 10 kHz/100 mu s native resolutions. Our data reveal a dual-precursor type feature in the pulse profile that is either faint or absent in high-frequency observations from Parkes. The resultant high-fidelity detections have enabled dispersion measure determinations with very high precision, of the order of (2-6) x 10(-6) pc cm(-3), owing to the microsecond level timing achievable for this pulsar at the MWA's low frequencies. This underscores the usefulness of low-frequency observations for probing the ISM toward PTA pulsars and informing optimal observing strategies for PTA experiments.
Conversion prevention in high alumina cement products.
Creators: name: Ding, Jian.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Engineering, Civil.

description: Mechanisms of stratlingite (C$\rm\sb2ASH\sb8)$ formation in the high alumina cement (HAC)--siliceous material--water systems were investigated. Different siliceous materials, e.g. natural zeolites, silica fume, fly ash, ground granulated blast-furnace slag, and different sodium salts, e.g. sodium silicate, sodium sulfate, etc. were employed. Reactions between CAH$\sb $ or C$\rm\sb2AH\sb8$ and dissolved silica occur. Acceleration of the silica dissolution by addition of chemical admixtures promoted the formation of stratlingite. A method for prevention of strength reduction of HAC products due to the conversion of thermodynamically unstable hexagonal calcium aluminates to cubic hydrogarnet is described. New conversion-preventing additives (CPA) to inhibit hydrogarnet formation in HAC products are described. Compressive strength development of HAC mortars containing the CPA additive was studied. The effect of curing conditions on strength development was also investigated. No strength reduction occurs for the HAC/CPA mortar water-cured at 38$\sp\circ$C. Stratlingite preferentially formed in the HAC paste containing the CPA additive. Durability of inhibited HAC products is also studied. Conversion inhibited high alumina cement binders have excellent characteristics for corrosion protection of reinforcement under severe test conditions. The HAC/CPA mortar can effectively resist the penetration of chloride ions. (Abstract shortened by UMI.)
Mainstreaming change: learning from community strengthening in Victoria
Creators: name: West, Sue
name: Wiseman, John
name: Bertone, Santina
Publisher: name: Swinburne
Year: 2024

description: This paper considers the lessons from community strengthening projects instigated under the Victorian State Government's Community Building Initiative and considers the implications of these lessons for future community strengthening policy and practice in Victoria. The first section of the paper explores the rise of more 'community' focused policy and practice in Australia, the drivers behind this approach, and the tensions and issues along the way. This is followed by an outline of the specific policy context of community strengthening in Victoria and the approach by the Victorian State Government since 1999. The paper suggests that the policy direction in Victoria has moved from a projects based approach to looking at ways of 'mainstreaming' community strengthening. The paper then considers the findings of a research project which sought to understand, from a practice perspective, what factors have contributed to successful community strengthening. It is suggested that a community centred approach to community strengthening is what works best. The final section of the paper considers what these findings mean in the context of a search for more 'mainstreamed' approaches to community strengthening and a number of key strategies are identified. The paper concludes with some comments about the implications of the lessons from the 'experimenting' phase for alternative public policy ideas.
Characterization of lamins A and C expression during differentiation of HL-60 cells towards monocytes/macrophages in vitro.
Creators: name: Carson, Christine.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Biology, Cell.

description: The inducible human promyelocytic cell line HL-60 is known to express a limited complement of intermediate filament proteins (IFPs). In the undifferentiated state these cells express B-type nuclear lamins, but lack lamins A and C and the cytoplasmic IFP vimentin (Paulin-Levasseur et al., 1988). In the present study, the HL-60 cell system was used to determine whether expression of lamins A and C was associated with the differentiated phenotype. HL-60 were treated with two different inducers of monocyte/macrophage differentiation: vitamin $\rm D\sb3$ and TPA. A detailed kinetic analysis of lamins A and C protein expression throughout the differentiation period was made using immunofluorescence microscopy (IFM). The expression of vimentin, the monocyte marker 63D3 and transferrin receptor (TR) were assessed in like manner. HL-60 proliferation was monitored by cell counts, $\sp3$H-thymidineincorporation and cell cycle analysis. Induction of HL-60 cell differentiation by vitamin $\rm D\sb3$ did not lead to expression of either lamins A/C or vimentin. Treatment with TPA, on the other hand, resulted in expression of these proteins in the vast majority of cells within 24 hours. Examination of marker expression and proliferation confirmed that both vitamin $\rm D\sb3$ and TPA induced differentiation in the treated cells. However, exposure to the vitamin resulted in cells which were monocyte-like, while TPA treatment gave rise to cells that more closely resembled macrophages. Lamins A/C expression was clearly not associated with growth arrest in the vitamin $\rm D\sb3$-treated cells, and was found to follow inhibition of replication in TPA-treated populations. It was determined that lamins A/C expression was not coincident with expression of the differentiated phenotype. These results suggested that lamins A/C expression was a post-differentiation event in the HL-60 cell system. (Abstract shortened by UMI.)
A profile of children living in shelters: Parents' perspectives on their children's health and factors that influence it.
Creators: name: Robeson, Paula Marie.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Health Sciences, Nursing.

description: Objective. To describe a profile of school-aged children (5--14 years) living in shelters in Ottawa including risk and protective factors commonly associated with health related outcomes in children. Design. A descriptive research study using a pre-tested survey questionnaire designed by the researcher, based on the literature, and guided by a resilience framework. Setting. Three emergency family shelters in Ottawa. Participants. 34 parents with 61 children (aged 5 to 14 years) living at the shelters. Conclusions. Risk and protective factors at the individual, family, and community levels are presented. Protective factors of children living in shelters should be recognised, strengthened, and maintained. Efforts to minimise the risk factors should be undertaken. Implications for nursing practice and research are discussed. (Abstract shortened by UMI.)
title: Increasing Independence in Students with Disabilities Through the Use of Visual Activity Schedules Within the General Education Classroom
Creators: name: Stevens, Natalie
Publisher: name: Utah State University
Year: 2022

description: Individuals with disabilities such as autism spectrum disorder (ASD) often require more prompts and specialized instruction than their peers in the school setting. These individuals often benefit from using Visual Activity Schedules (VAS) to learn to complete routines and increase independence while decreasing the needs for adult help and prompts. This study uses VAS plus prompting to increase independence in three children with ASD within the general education elementary classroom. During the study, VAS were introduced and paired with specific prompts aimed to help students become more independent at completing a given routine throughout their school day. Results from the study indicate that using activity schedules with specific prompts resulted in an increase in independent task completion and a decrease in adult prompting across all three participants.