cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ASSESSING FOREST RESOURCES AND THEIR ROLE IN FOSTERING SUSTAINABLE RURAL LIVELIHOODS: AN INVESTIGATION INTO THE SUB-DIVISIONS OF DARJEELING HILLS, WEST BENGAL
Creators: name: NOEL GIRI
name: Dr. P. MURUGESAN
Publisher: name: Zenodo
Year: 2023
Subjects: Forest Resources, Rural development, Sustainability, Darjeeling Hills, Rural Community, Forest Community, Rural Livelihood.

description: Abstract
Promoting sustainable rural development through the utilization of natural forest resources holds significant potential for enhancing rural livelihoods. It is imperative not to disregard issues concerning forest resources and their impact on rural livelihoods when making policy decisions and implementing interventions. Therefore, it is essential for various agencies to take proactive measures to ensure the efficient and responsible utilization of forest resources, as this stands as an effective means of enhancing the well-being of rural households. The study also underscores the lack of attention given to the cultural, traditional, and environmental value of forest resources in the Darjeeling hills. Awareness programs conducted by both governmental and non-governmental organizations in the study area are limited. Furthermore, some communal areas created through land reform processes often need to pursue their development independently, facing minimal or no external assistance. It has been observed that rural households employ a variety of livelihood strategies beyond agriculture and forestry income. Active involvement of local communities is pivotal in achieving sustainable development objectives.
Lumpy AdS$\bf{_5\times}$ S$\bf{^5}$ Black Holes and Black Belts
Creators: name: Dias, Oscar J. C.
name: Santos, Jorge E.
name: Way, Benson
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Sufficiently small Schwarzschild black holes in global AdS$_5\times$S$^5$ are Gregory-Laflamme unstable. We construct new families of black hole solutions that bifurcate from the onset of this instability and break the full SO$(6)$ symmetry group of the S$^5$ down to SO$(5)$. These new "lumpy" solutions are labelled by the harmonics $\ell$. We find evidence that the $\ell = 1$ branch never dominates the microcanonical/canonical ensembles and connects through a topology-changing merger to a localised black hole solution with S$^8$ topology. We argue that these S$^8$ black holes should become the dominant phase in the microcanonical ensemble for small enough energies, and that the transition to Schwarzschild black holes is first order. Furthermore, we find two branches of solutions with $\ell = 2$. We expect one of these branches to connect to a solution containing two localised black holes, while the other branch connects to a black hole solution with horizon topology $\mathrm S^4\times\mathrm S^4$ which we call a "black belt".
description: 20 pages (plus 17 pages for Appendix on Kaluza-Klein Holography), 14 figures
title: Inequality in outcome for oesophago-gastric cancer in England : is there an association with gastroscopy rates in general practice populations?
Creators: name: Shawihdi, Mustafa
Publisher: name: University of Liverpool Repository
Year: 2014

description: Introduction: Oesophago-gastric (OG) cancers remain a worldwide challenge with little sign of major improvements in survival rates. Modern guidelines focus on alarm (or ‘red flag’) symptoms as key triggers for gastroscopy and recommend empirical symptomatic treatment and non-invasive H. pylori testing in those with simple dyspepsia. However, the early symptoms of OG cancer are very common and non-specific, and the traditional alarm symptoms have poor sensitivity or specificity for malignancy. Diagnosis therefore necessitates investigation of symptoms though upper GI endoscopy in a relatively large group of patients, most of whom do not have malignant disease. This has fuelled considerable controversy regarding the role for gastroscopy in detecting cancer at a treatable stage. Objectives: Firstly, to develop data extraction and linkage methods for studying OG cancer outcome, and General Practice population rates of elective diagnostic gastroscopy, using administrative data for English hospitals (Hospital Episode Statistics). Secondly, to confirm the face-validity of the methodology using external sources of information and local audit data. Thirdly, to test the hypothesis that variations in rates of gastroscopy in English General Practice (GP) populations are associated with inequalities in OG cancer outcome. Fourthly, to explore whether practices with lower rates of gastroscopy exhibit a higher yield of serious pathology, consistent with more selective referral practice. Fifthly, to confirm the existence of wide variation in gastroscopy rate between practices in close geographical proximity, Design and methods: Analysis of Hospital Episode Statistics (2006-8) linked to death registry and practice population data. General practices with new cases of OG cancer were included, grouped into tertiles according to standardised elective gastroscopy rate per capita (low, medium or high). Outcome measures for cancer cases were: emergency admission during diagnostic pathway; major surgical resection and mortality at 1 year. Co-variates were age, gender, co-morbidity, and deprivation. Associations between the gastroscopy rate at the patient’s general practice and cancer outcomes were tested in binary logistic regression models, with extensive sensitivity testing of gastroscopy rate ‘exposure’ variable. An algorithm was developed to analyse coded diagnoses for all first elective gastroscopies, using both national and local audit data. Practices were mapped based on postal code. Results: 22,488 incident cases of OG cancer from 6,513 general practices. Mean OGD rate for Low, Middle, High practices: 4.4 vs 8.1 vs 12.9 per 1,000. Mean age of patients undergoing OGD was highest for low tertile practices (60.2 vs 59.5 vs 58.4 yrs; p
Emergence of Spontaneously Broken Supersymmetry on an Anti-D3-Brane in KKLT dS Vacua
Creators: name: Kallosh, Renata
name: Wrase, Timm
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The KKLT construction of de Sitter vacua includes an uplifting term coming from an anti-D3-brane. Here we show how this term can arise via spontaneous breaking of supersymmetry, based on the emergence of a nilpotent chiral supermultiplet on the world-volume of the anti-D3-brane. We establish and use the fact that both the DBI as well as the WZ term, with account of orientifolding, acquire a form of the Volkov-Akulov action. For an O3 orientifold involution of $\mathbb{R}^{9,1}$ we demonstrate the cancellation between the fermionic parts of the DBI and WZ term for the D3-brane action. For the anti-D3-brane we show that the DBI action and the WZ action combine and lead to the emergence of the goldstino multiplet which is responsible for spontaneous breaking of supersymmetry. This provides a string theoretic explanation for the supersymmetric uplifting term in the KKLT effective supergravity model supplemented by a nilpotent chiral multiplet.
description: 17 pages; v2: added clarifying comments and a reference
Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis
Creators: name: Brouwer, Kim L. R.
name: Sidney Barritt, A.
name: Xie, Guoxiang
name: Ferslew, Brian C.
name: Jia, Wei
name: Johnston, Curtis K.
name: Stewart, Paul W.
name: Su, Mingming
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The prevalence of non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) is increasing at an alarming rate. The role of bile acids in the development and progression of NAFLD to NASH and cirrhosis is poorly understood. This study aimed to quantify the bile acid metabolome in healthy subjects and patients with non-cirrhotic NASH under fasting conditions and after a standardized meal.
Looking Back to Look Forward: Reanimating Textiles for Novel Design and Manufacturing
Creators: name: Hagan, Brooks
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Exhibit presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
title: Reconstructing historical sea-level trends for the Croatian coast of the Adriatic Sea using salt-marsh foraminifera
Creators: name: Shaw, Timothy
Publisher: name: University of Liverpool Repository
Year: 2014

description: The application of salt-marsh foraminifera to reconstruct historical sea-level trends was investigated for the Croatian coast of the Adriatic Sea using a transfer function approach. This technique, whilst well practised from north Atlantic sites along the shores of America and UK, has previously evaded any published study in the Mediterranean region. A total of 70 surface samples were collected across separate transects established at two micro-tidal salt-marsh sites from the central Croatian coastline to establish a modern dataset of foraminifera. In addition, environmental variables were also investigated including salinity, pH, organic matter, particle size, distance (from open water) and altitude, relative to the Croatian national datum. Three sediment cores were sampled for fossil foraminifera and composite chronologies involving short-lived radionuclides, radiocarbon dating and pollution indicators from XRF. Age-depth models were created using classical and Bayesian approaches. Quantitative analysis of the foraminiferal assemblages revealed on average three faunal zones in which characteristic species occurred. This comprised a faunal zone composed almost exclusively of agglutinated species; J. macrescens, T. inflata and M. fusca extending between mean tidal level (MTL) and beyond MHWST (higher altitude). A second faunal zone was more variable and comprised of a mixed assemblage of agglutinated species described above in addition to calcareous species; Ammonia spp., Elphidium spp., Haynesina germanica and Quinqueloculina spp. This zone spanned a large vertical range above and below MTL. In a third faunal zone calcareous species dominated and was restricted to the lower altitudes of the salt-marsh environments. Further quantitative measures were employed to test the hypothesis that foraminiferal distributions were controlled by altitude. Partial ordination techniques revealed altitude as a statistically significant control confirming their suitability as proxies for sea-level in transfer function reconstructions. An analysis of species environment relationships revealed strong linear response suggesting the use of PLS regression models. Transfer functions were then developed for both site specific and a total combined dataset, where small r2 jack values largely reflected the short environmental gradients despite relatively low predictions errors (RMSEP jack =
Latitudinal Distribution of the Photospheric Magnetic Fields of Different Magnitudes
Creators: name: Vernova, E. S.
name: Tyasto, M. I.
name: Baranov, D. G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Photospheric magnetic fields are studied using synoptic maps from 1976 to 2003 produced at the National Solar Observatory, Kitt Peak (NSO/KP). Synoptic maps were averaged over the time interval of nearly three solar cycles (Solar Cycles 21-23). The change in the latitudinal distribution was considered for the following groups of magnetic field values: B = 0-5 G, B = 5-15 G, B = 15-50 G, and B>50 G. Magnetic fields in each of the above groups have common latitudinal distribution features, while for different field groups these features are significantly different. Each of the groups is closely related to a certain manifestation of solar activity. Strong magnetic fields are connected with two types of solar activity: active regions (magnetic fields B>15 G)that are related to sunspot zones, and polar faculae (magnetic fields 50 G > B > 15 G) that occupy latitudes around 65$^\circ$-75$^\circ$. Fields from 5 to 15 G occupy the polar regions and are connected with polar coronal holes (the global solar dipole). Fields of B<5 G occupy a) the equatorial region and b) latitudes 40$^{\circ}$-60$^\circ$.
description: 11 pages, 8 figures
Nicalimnesia andha Cook 1967
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Limnesiidae
Nicalimnesia
Nicalimnesia andha

description: Nicalimnesia andha Cook, 1967
Records from the study area: Maharashtra, Karnataka, Kerala—Cook (1967); Prasad (1974); Pešić & Ranga Reddy (2009).
Habitat: Hyporheic interstitial.
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 24, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: the Johnston County Osteoarthritis Project
Creators: name: Kraus, Virginia B.
name: Schwartz, Todd A.
name: Elstad, Emily
name: Nelson, Amanda E.
name: Conaghan, Philip G.
name: Renner, Jordan B.
name: Jordan, Joanne M.
name: Golightly, Yvonne M.
name: DeVellis, Robert F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: To determine associations between multiple joint symptoms and radiographic osteoarthritis (rOA) and functional outcomes.
Toolkit for Researcher Career Development
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: The deliverable Toolkit for Researcher Career Development, produced by WP3, is an informative tool that aims to provide an intuitive summary of the different opportunities that the EC2U Alliance has to offer to its community, specifically for those working in Research and Innovation activities. Moreover, it provides access to all the resources produced by the Research and Innovation for Cities and Citizens (RI4C2) project, which serves as the link between the EC2U Alliance and the Research and Innovation dimension of its member universities.The Toolkit for Researcher Career Development can now be accessed on the EC2U Tools Page, which is referenced on the EC2U website.
Convexity for Hamiltonian torus actions on $b$-symplectic manifolds
Creators: name: Guillemin, Victor
name: Miranda, Eva
name: Pires, Ana Rita
name: Scott, Geoffrey
Publisher: name: arXiv
Year: 2014
Subjects: subject: Symplectic Geometry (math.SG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53D05, 53D17, 53D20

description: In [GMPS] we proved that the moment map image of a $b$-symplectic toric manifold is a convex $b$-polytope. In this paper we obtain convexity results for the more general case of non-toric hamiltonian torus actions on $b$-symplectic manifolds. The modular weights of the action on the connected components of the exceptional hypersurface play a fundamental role: either they are all zero and the moment map behaves as in classic symplectic one, or they are all nonzero and the moment map behaves as in the toric $b$-symplectic case studied in [GMPS].
description: 12 pages final version to appear at Mathematical Research Letters
Parent management of the school reintegration needs of children and youth following moderate or severe traumatic brain injury
Creators: name: Fleig, Denise K.
name: Knafl, Kathleen A.
name: Roscigno, Cecelia I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: School reintegration following children’s traumatic brain injury (TBI) is still poorly understood from families’ perspectives. We aimed to understand how both unique and common experiences during children’s school reintegration were explained by parents to influence the family.
The Service Shirt: ultra-slow fashion textile design research for industry
Creators: name: Earley, Rebecca
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Exhibit presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Reengineered AAV Vectors: Old Dog, New Tricks
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Adeno-Associated Viral (AAV) vectors have emerged in recent years as powerful tools for therapeutic gene transfer. Successes in clinical trials and the discovery of several hundreds of naturally occurring AAV isolates have triggered efforts to understand and manipulate this deceptively simple parvovirus for a myriad of gene therapy applications. Exciting breakthroughs based on directed evolution of novel tissue-specific variants from combinatorial AAV libraries have been reported. Recent approaches driven by the availability of structural information have yielded a new generation of reengineered AAV vectors.
Museum history at the service of new EU-funded museum projects. The Necropolis of Tarragona
Creators: name: Cecalupo, Chiara
Publisher: name: Zenodo
Year: 2023
Subjects: Museum
Archaeology
EU-Pillar
Heritage

description: This is a short report of a recent activity in field of museology that provides an example on how historiography and cultural research on European archaeology and museums may be useful for policy making when it comes to enhance cultural heritage sites. It tells in brief how the Marie-Curie Cofund project “LIT! Living in the Catacombs” is contributing to the planning of the new museum of the necropolis of Tarragona after it was awarded funds from Next Generation EU.
Recent Gene Therapy Advancements for Neurological Diseases
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The past few years have seen rapid advancements in vector-mediated gene transfer to the nervous system and modest successes in human gene therapy trials. The purpose of this review is to describe commonly-used viral gene transfer vectors and recent advancements towards producing meaningful gene-based treatments for central nervous system (CNS) disorders. Gene therapy trials for Canavan disease, Batten disease, adrenoleukodystrophy, and Parkinson’s disease are discussed to illustrate the current state of clinical gene transfer to the CNS. Preclinical studies are under way for a number of diseases, primarily lysosomal storage disorders, using a newer generation of vectors and delivery strategies. Relevant studies in animal models are highlighted for Mucopolysaccharidosis IIB and Krabbe disease to provide a prelude for what can be expected in the coming years for human gene transfer trials, using recent advancements in gene transfer technology. In conclusion, recent improvements in CNS gene transfer technology are expected to significantly increase the degree of disease rescue in future CNS-directed clinical trials, exceeding the modest clinical successes that have been observed so far.
Viral Expression Cassette Elements to Enhance Transgene Target Specificity and Expression in Gene Therapy
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Over the last five years, the number of clinical trials involving AAV (adeno-associated virus) and lentiviral vectors continue to increase by about 150 trials each year. For continued success, AAV and lentiviral expression cassettes need to be designed to meet each disease's specific needs. This review discusses how viral vector expression cassettes can be engineered with elements to enhance target specificity and increase transgene expression. The key differences relating to target specificity between ubiquitous and tissue-specific promoters are discussed, as well as how endogenous miRNAs and their target sequences have been used to restrict transgene expression. Specifically, relevant studies indicating how cis-acting elements such as introns, WPRE, polyadenylation signals, and the CMV enhancer are highlighted to show their utility for enhancing transgene expression in gene therapy applications. All discussion bears in mind that expression cassettes have space constraints. In conclusion, this review can serve as a menu of vector genome design elements and their cost in terms of space to thoughtfully engineer viral vectors for gene therapy.
The two molecular clouds in RCW 38; evidence for formation of the youngest super star cluster in the Milky Way triggered by cloud-cloud collision
Creators: name: Fukui, Y.
name: Torii, K.
name: Ohama, A.
name: Hasegawa, K.
name: Hattori, Y.
name: Sano, H.
name: Ohashi, S.
name: Fujii, K.
name: Kuwahara, S.
name: Mizuno, N.
name: Dawson, J. R.
name: Yamamoto, H.
name: Tachihara, K.
name: Okuda, T.
name: Onishi, T.
name: Mizuno, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present distributions of two molecular clouds having velocities of 2 km s$^{-1}$ and 14 km s$^{-1}$ toward RCW 38, the youngest super star cluster in the Milky Way, in the $^{12}$CO ($J=$1--0 and 3--2) and $^{13}$CO ($J=$1--0) transitions. The two clouds are likely physically associated with the cluster as verified by the high intensity ratio of the $J$=3--2 emission to the $J$=1--0 emission, the bridging feature connecting the two clouds in velocity and their morphological correspondence with the infrared dust emission. The total mass of the clouds and the cluster is too small to gravitationally bind the velocity difference. We frame a hypothesis that the two clouds are colliding with each other by chance to trigger formation of the $\sim$20 candidate O stars which are localized within $\sim$0.3 pc of the cluster center in the 2 km s$^{-1}$ cloud. We suggest that the collision is currently continuing toward part of the 2 km s$^{-1}$ cloud where the bridging feature is localized. This is the third super star cluster alongside of Westerlund2 and NGC3603 where cloud-cloud collision triggered the cluster formation. RCW38 is the most remarkable and youngest cluster, holding a possible sign of on-going O star formation, and is the most promising site where we may be able to witness the moment of O-star formation.
title: Multifunctional catalysts for the one-step conversion of acetone to methyl isobutyl ketone
Creators: name: Hetterley, Robert
Publisher: name: University of Liverpool Repository
Year: 2023

description: Three contrasting classes of solid acid-base materials have been impregnated with palladium to produce active multifunctional catalysts for the one-step conversion of acetone to methyl isobutyl ketone (MIBK), an industrially important solvent. The Pd supported heteropolyacid, Pd/Cs2.5Ho.5PWi204o (Pd/Cs2.5PW), known to possess Bronsted acid sites high in strength, was tested in both liquid phase and gas phase reaction conditions [1]. The Pd/Cs2.5PW catalysts with low Pd concentration proved to be significantly more active in the liquid phase with a Pd loading of 0.1 wt% proving to be sufficient to give acetone conversions of up to 55% at over 90% MIBK selectivity, achieved at a temperature range of 180-200 °C. 1.
title: From transfer hydrogenation to transamination: new methods for the preparation of N-Heterocycles
Creators: name: Wu, Jianjun
Publisher: name: University of Liverpool Repository
Year: 2014

description: Reduction of N-heteroaromatic compounds is a challenging and important reaction. Transfer hydrogenation using organic molecules as hydrogen donors is a safe and operationally simple alternative to hydrogenation with H2. However, it has been underutilised and less developed. In this thesis, our contribution to the transfer hydrogenation of N-heteroaromatic compounds is described. Following a brief introduction of transfer hydrogenation of N-heteroaromatic compounds in Chapter 1, Chapter 2 presents a novel method for the mild reduction of quinolines, isoquinolines and quinoxalines to corresponding tetrahydro products. The most significant discovery is the remarkable accelerating effect of the simple iodide ion, which acts presumably by altering the reaction mechanism. Chapter 3 extends the above-mentioned system to the reduction of more challenging pyridines to afford not only piperidines but also the 3,4-unsaturated variants with high chemoselectivities. Chapter 4 describes a simple, complementary system, discovered during searching for new transfer hydrogenation catalysts, which allows for the hydrogenation of N-heteroaromatics with H2 using a cyclometalated iridium complex under exceptionally mild conditions (ambient temperature, 1 atm H2) in the absence of any additives. Chapter 5 demonstrates a new reaction for the rapid and direct preparation of various chiral piperidines from pyridines with high yields and exceptional diastereo- and enantioselectivities. Key to the success is the introduction of a chiral amine which is incorporated into the pyridine ring by transamination during the transfer hydrogenation process, presumably via forming previously unobtainable chiral tetrahydropyridinium intermediate in situ.
Die Förderung exekutiver Funktionen und die Verbesserung des Umgangs mit Verhaltensauffälligkeiten durch die gemeinsame Nutzung des Bilderbuchs «Ein verknottertes Schlüsselerlebnis» bei Kindern
Creators: name: Miljko, Ema
Publisher: name: Zenodo
Year: 2023
Subjects: Sonderpädagogik
Masterarbeit
Exekutive Funktionen
Verhaltensauffälligkeit

description: Die vorliegende Masterarbeit untersucht die Wirksamkeit des Bilderbuchs "Ein verknottertes Schlüsselerlebnis" in Zusammenarbeit mit Eltern zur Förderung exekutiver Funktionen bei Kindern und zur Reduzierung von Verhaltensauffälligkeiten. Exekutive Funktionen sind grundlegende kognitive Fähigkeiten, die für akademischen Erfolg, soziale Kompetenz und emotionale Intelligenz unerlässlich sind.
Die Forschungsfrage lautet: Inwieweit kann die gemeinsame Nutzung des Bilderbuchs «Ein verknottertes Schlüsselerlebnis» durch Eltern und Kinder dazu beitragen, exekutive Funktionen bei Kindern zu fördern und den Umgang mit Verhaltensauffälligkeiten zu verbessern? Um diese Frage zu beantworten, wird ein deskriptives, multi-methodisches Forschungsdesign verwendet, das auf der Analyse von Fragebögen basiert, welche von Klassenlehrpersonen und Eltern ausgefüllt wurden.
Die Stichprobe besteht aus Kindern mit Auffälligkeiten in den exekutiven Funktionen, ihren Erziehungsberechtigten und Klassenlehrpersonen. Die Intervention umfasst die Nutzung des Bilderbuchs zur Förderung exekutiver Funktionen über einen Zeitraum von einem Monat. Die Studie kombiniert qualitative und quantitative Ansätze zur Auswertung der erhobenen Daten.
Die Ergebnisse deuten darauf hin, dass der Einsatz des Bilderbuchs die Eltern-Kind-Beziehung stärken, die Motivation der Kinder erhöhen und sich positiv auf das Klassenklima auswirken kann. Darüber hinaus glauben die meisten Lehrpersonen und Eltern, dass das Bilderbuch zur Entwicklung der exekutiven Funktionen bei Kindern beitragen kann. Die Arbeit liefert wertvolle Einblicke in das Potenzial von Bilderbüchern zur Förderung der exekutiven Funktionen und zur Bewältigung von Verhaltensproblemen bei Kindern.
'Nonahedra' Virtual Fashion Film
Creators: name: Homewood, Rachel
name: Counsell, Alex
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Short paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Creation of four new Virtual Institutes
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: This report focuses on the formal and administrative establishment of four new Virtual Institutes within the EC2U Alliance. The creation of these new Virtual Institutes is part of the EC2U R&I Agenda that was designed through dialogues with Vice-Rectors of Research, Rectors and partner universities research support offices.
Hospitalizations for Cardiovascular Disease in African Americans and Whites with HIV/AIDS
Creators: name: Lawson, Kenneth A.
name: Koeller, Jim M.
name: Morse, Gene D.
name: Frei, Christopher R.
name: Oramasionwu, Christine U.
name: Brown, Carolyn M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Therapeutic advances have resulted in an epidemiological shift in the predominant causes of hospitalization for patients with HIV/AIDS. An emerging cause for hospitalization in this patient population is cardiovascular disease (CVD); however, data are limited regarding how this shift affects different racial groups. The objective of this observational, retrospective study was to evaluate the association between race and hospitalization for CVD in African Americans and whites with HIV/AIDS and to compare the types of CVD-related hospitalizations between African Americans and whites with HIV/AIDS. Approximately 1.5 million hospital discharges from the US National Hospital Discharge Surveys for the years of 1996 to 2008 were identified. After controlling for potential confounders, the odds of CVD-related hospitalization in patients with HIV/AIDS were 45% higher for African Americans than whites (odds ratio [OR]=1.45, 95% CI, 1.39–1.51). Other covariates that were associated with increased odds of hospitalization for CVD included chronic kidney disease (OR=1.43, 95% CI, 1.36–1.51), age≥50 years (OR=3.22, 95% CI, 2.94–3.54), region in the Southern United States (OR=1.17, 95% CI, 1.11–1.23), and Medicare insurance coverage (OR=1.71, 95% CI, 1.60–1.83). Male sex was not significantly associated with the study outcome (OR=0.99, 95% CI, 0.96–1.02). Compared to whites with HIV/AIDS, African Americans with HIV/AIDS had more hospitalizations for heart failure and hypertension, but fewer hospitalizations for stroke and coronary heart disease. In conclusion, African Americans with HIV/AIDS have increased odds of CVD-related hospitalization as compared to whites with HIV/AIDS. Furthermore, the most common types of CVD-related hospitalizations differ significantly in African Americans and whites. (Population Health Management 2012;16:201–207)
title: Dielectric relaxation and frequency dependence of Hf02 doped by lanthanide elements
Creators: name: Zhao, Chun
Publisher: name: University of Liverpool Repository
Year: 2014

description: The decreasing sizes in complementary metal oxide semiconductor (CMOS) transistor technology requires the replacement of SiO2 with gate dielectrics that have a high dielectric constant (k). When the SiO2 gate thickness was reduced below 1.4 nm, electron tunneling effects and high leakage currents occurred which presented serious obstacles for the reliability issue in terms of metal-oxide-semiconductor field-effect transistor (MOSFET) devices. In recent years, various alternative gate dielectrics have been researched. Following the introduction of HfO2 into the 45 nm process by Intel in 2007, the screening and selection of high-k gate stacks, understanding their properties, and their integration into CMOS technology has been a very active research area. Frequency dispersion of high-k dielectrics was commonly observed and classified into two parts: extrinsic and intrinsic causes. The frequency dependence of the dielectric constant (k-value), that is the intrinsic frequency dispersion, could not be assessed before suppressing the effects of extrinsic frequency dispersion, such as the effects of the lossy interfacial layer (between the high-k thin film and silicon substrate) and the parasitic effects. The significance of parasitic effects (including series resistance and the back metal contact of the metal-oxide-semiconductor (MOS) capacitor) on frequency dispersion was studied. The effect of the lossy interfacial layer on frequency dispersion was investigated and modeled using a dual frequency technique. The effect of surface roughness on frequency dispersion is also investigated. Several mathematical models were discussed to describe the dielectric relaxation of high-k dielectrics. Some of the relaxation behavior can be modeled using the Curie-von Schweidler (CS) law, the Kohlrausch-Williams-Watts (KWW) relationship and the Havriliak-Negami (HN) relationship. Other relaxation models were also introduced. For the physical mechanism, dielectric relaxation was found to be related to the degree of polarization, which was dependent on the structure of the high-k material. The degree of polarization was attributed to the enhancement of the correlations among polar nano-scale size domain within the materials. The effect of grain size for the high-k materials' structure mainly originated from higher surface stress in smaller grain size due to its higher concentration of grain boundary.
EC2U R&I agenda
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: This report describes a comprehensive and participative process initiated in April 2023, intended to be a consensus-building initiative, and expected to deliver a common Research and Innovation agenda for the next 10 years, together with the tools for its implementation within the EC2U Alliance (4 Virtual Institutes as defined in the RI4C2 Project Proposal). The process involved Vice-Rectors for Research and Innovation, Research Managers, and Support Officers, aiming at drawing up a common EC2U Research and Innovation (R&I) Agenda. The initiation of this R&I agenda represents our Alliance’s efforts towards the achievement of one of the SwafS transformation modules established by the European Commission for convergent R&I actions of European University Alliances.
title: The structural characterisation of two DNA protectants during stress; the tandem RRM domains of mouse TDP-43 and E.coli DPS
Creators: name: Austin, James
Publisher: name: University of Liverpool Repository
Year: 2014

description: TAR DNA Binding protein (TDP-43) is a member of the heterogeneous nuclear ribonucleoprotein family with crucial splicing, transport and regulatory function of genetic material inside mammalian cells. Unfortunately, TDP-43 positive cytoplasmic aggregates occurring with post-translational modifications are a common hallmark in neurodegenerative diseases observed in Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis (ALS) and fronto-temporal lobar degeneration (FTLD) diseases. Mutations in the TARDBP gene responsible for encoding TDP-43, have been directly correlated with onset of ALS and FLTD. Disease models describing TDP-43 proteinopathy suggests onset may derive through either cytoplasmic mis-localisation or a loss of nuclear function but it is unclear if or how disease associated point-mutations contribute to these observations. In order to determine the effects these mutations have on the protein, a fragment containing the tandem RRM domains (residues 101-265), responsible for the proteins nucleic acid binding function was tested. Using small angle X-ray scattering, circular dichroism, isothermal titration calorimetry and thermal assay methodology it was demonstrated that initial structures of all variants are similar but mutations (D169G and K263E) confer resistance to thermal denaturation by up to 4.9 ± 0.6˚C. This stability positively correlated with an increase in half-life when tested in the full-length variant using a neuron cell model suggesting that protein turn-over is a contributing disease factor. This study was also concerned with solving an X-ray crystallographic DNA binding complex structure for E.coli DPS and mapping interactions with neighbouring DPS complexes. These mechanisms are important in DPS function to protect nucleic acids during prokaryote stress. DPS is conserved in almost all prokaryotes however not all species can interact with DNA. Using X-ray crystallography, a model of E.coli DPS was built to 2.8 Å resolution from DNA containing samples showing both DNA and N-terminal residues were absent. Stabilising polar interactions were shown to form between neighbouring dodecamer structures involving T12, R18, D20, N99, S100, S106 and K134. Polar contacts are observed in all compared crystallographic structures from different species but the residues involved are poorly conserved, despite strong similarities between sequence and structure. This suggests that these contacts may contribute to stabilising the DNA-DPS complexes but form indiscriminately between exposed polar residues available on the dodecamer surface. These interactions are likely to contribute to the thermal stability of DNA-DPS complexes to aid in the proteins protective function.
title: The definition and measurement of neurological fatigue in multiple sclerosis
Creators: name: John Mills, Roger
Publisher: name: University of Liverpool Repository
Year: 2023

description: Background Fatigue is one of the most complex and severely disabling symptoms in multiple sclerosis (MS). There is an absence of a clear definition of fatigue and Uttle consensus exists on its relationship to the other features of MS. The underlying pathophysiology of MS fatigue is unknown and there are no effective treatments. Fatigue has been thought of as difficult to define and usually considered to be multidimensional. These two points, however, immediately present a paradox for the measurement of fatigue, since the fundamental principles of measurement require both strict definition and unidimensionality. The central hypothesis was that the phenomenon of fatigue, as a symptom in multiple sclerosis, could be defined in a detailed and coherent way and could then be measured, in order to facilitate understanding of its pathophysiology. The hypothesis was proven and in doing so many questions regarding the fundamental nature of atigue in MS were answered. It also provided the basis from which to pose questions, in a logical manner, regarding the underlying pathophysiology of the symptom.
title: Investigating employability: the perspective of the business school graduate
Creators: name: Jackson, Victoria
Publisher: name: University of Liverpool Repository
Year: 2014

description: Graduate employability is a current and high profile concept, which has received much attention over recent decades. This attention however, has mostly centred on employer perspectives and their views regarding skill demands or shortfalls. Where the graduate viewpoint has been sought, this has largely involved the mass collection of career destination and employment outcome information (Woodley & Brennan, 2000; Tomlinson, 2007; Holmes, 2013). This career destination approach however, has been criticised for its simplicity, with arguments that it is not an accurate measure of employability (Harvey, 2001; Tymon, 2011). As a consequence, the graduate perspective of their employability enhancement is an under-researched and largely neglected area, resulting in a lack of understanding of this particular viewpoint (Nabi & Bagley, 1999; Harvey, 1999; Nabi, 2003; Shah et al. 2004; Sleep & Reed, 2006; Rothwell et al. 2009). To address this situation, the overall aim of this research is to investigate employability from the graduate perspective, and to research this within the context of the current economic climate. The critical realist philosophy was adopted for this research, which supports the implementation of a multiple case study methodology, utilising mixed data collection methods. Employing this approach, three key employability stakeholder perspectives were collected and analysed: graduates, curriculum developers and employers. A fourth stakeholder view, the policy makers, was obtained from secondary sources comprising of recent policy documents. Addressing the four stakeholder perspectives assists in the acquisition of a holistic understanding of the graduate employability concept. This facilitates the connection of the graduate perspective to those of the other stakeholders, which is currently lacking in the employability literature (Andrews & Higson, 2008). A range of interesting employability perspectives were produced, which most notably highlighted the importance of the type of institution attended, employer focuses upon behaviours over skills, and the significance of the prevailing economic climate. These fresh insights were incorporated into a revised model of graduate employability. The original contribution to knowledge is threefold. Firstly, a deeper understanding of the graduate perspective has been obtained. Secondly, clarity over employer requirements has been produced, and thirdly, the economic climate and labour market conditions have increased awareness of the effect these have upon stakeholder perceptions of graduate employability.
title: Functional outcomes after coronary artery bypass surgery
Creators: name: Sophia Groom, Christina
Publisher: name: University of Liverpool Repository
Year: 2023

description: Cardiopulmonary Bypass (CPB) isolates the heart from the circulatory system. As a result, Coronary Artery Bypass Graft (CABG) surgery has become a common treatment for coronary artery disease (CAD) relieving angina and improving health related quality of life (HRQOL) and mood. However, CABG has been associated with Central Nervous System (CNS) dysfunction and successful surgery can be marred by cognitive impairment and/or poor HRQOL/ mood.
Health Care Savings with the Patient-Centered Medical Home: Community Care of North Carolina's Experience
Creators: name: Fillmore, Herbert
name: Jackson, Carlos T.
name: DuBard, C. Annette
name: Ritter, Grant A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: This study evaluated the financial impact of integrating a systemic care management intervention program (Community Care of North Carolina) with person-centered medical homes throughout North Carolina for non-elderly Medicaid recipients with disabilities during almost 5 years of program history. It examined Medicaid claims for 169,676 non-elderly Medicaid recipients with disabilities from January 2007 through third quarter 2011. Two models were used to estimate the program's impact on cost, within each year. The first employed a mixed model comparing member experiences in enrolled versus unenrolled months, accounting for regional differences as fixed effects and within physician group experience as random effects. The second was a pre-post, intervention/comparison group, difference-in-differences mixed model, which directly matched cohort samples of enrolled and unenrolled members on strata of preenrollment pharmacy use, race, age, year, months in pre-post periods, health status, and behavioral health history. The study team found significant cost avoidance associated with program enrollment for the non-elderly disabled population after the first years, savings that increased with length of time in the program. The impact of the program was greater in persons with multiple chronic disease conditions. By providing targeted care management interventions, aligned with person-centered medical homes, the Community Care of North Carolina program achieved significant savings for a high-risk population in the North Carolina Medicaid program. (Population Health Management 2013;17:141–148)
User Experience Study of Screen Readers for Visually Challenged Users
Creators: name: Hegde, Monica
Publisher: name: Purdue University Graduate School
Year: 2023
Subjects: classificationCode: 460806
subject: Human-computer interaction

description: The study investigates the user experience of visually impaired people using screen readers, concentrating on their accessibility and usability when navigating digital content. Screen readers are indispensable instruments for the blind and visually impaired, facilitating the completion of online tasks and access to information. While screen readers offer benefits such as customization and accessibility, they also present users with challenges such as cognitive burden, sequential navigation, and limitations with multimedia content.The research takes a user-centric approach, taking into account the particular requirements and preferences of visually impaired users. By conducting empirical research, the study gains valuable insights into the experiences, requirements, and pain points of screen reader users. The objective is to identify areas for enhancement and create solutions that enhance the user's efficiency and satisfaction.Recognizing the diverse subcategories within the visually impaired population, the thesis argues for design approaches that are tailored to specific needs. In addition, the incorporation of existing artificial intelligence systems, such as image caption generation and text extraction, is investigated to improve the functionality and usability of screen readers.Through this research, the thesis emphasizes the significance of creating digital content that is both functional and accessible. By embracing the curb cut effect and incorporating empirical research findings, developers can cultivate a more inclusive and equitable online environment for all users, thereby promoting inclusivity and ensuring that visually impaired users can effectively interact with digital content.
Imaginative Empathy and use of Somatic Perceptions in the Designing of a Therapeutic mask for Diabetic Retinopathy
Creators: name: Morehead, Sarah
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Survey on R&I Needs of the EC2U Alliance
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: This report presents the results of a large-scale survey on R&I needs that was carried out among the seven EC2U university communities (research groups, PhD students, etc.), the seven EC2U city and regional administrations, all EC2U associated partners (chambers of commerce, R&I parks, etc.) and a selection of other economic, social and cultural stakeholders (local and regional enterprises, citizens, cultural organisations, etc.) to (1) identifying priority interdisciplinary research and innovation activities that should be carried out inside the three existing EC2U Virtual Institutes (VI for Health and Well-Being, VI for Quality Education - Language and Cultural Diversity, VI for Sustainable Cities and Communities) and (2) to identify the main research topics of the new EC2U Virtual Institutes.