cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Change of variable in spaces of mixed smoothness and numerical integration of multivariate functions on the unit cube
Creators: name: Nguyen, Van Kien
name: Ullrich, Mario
name: Ullrich, Tino
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: In a recent article by two of the present authors it turned out that Frolov's cubature formulae are optimal and universal for various settings (Besov-Triebel-Lizorkin spaces) of functions with dominating mixed smoothness. Those cubature formulae go well together with functions supported inside the unit cube $[0,1]^d$. The question for the optimal numerical integration of multivariate functions with non-trivial boundary data, in particular non-periodic functions, arises. In this paper we give a general result that the asymptotic rate of the minimal worst-case integration error is not affected by boundary conditions in the above mentioned spaces. In fact, we propose two tailored modifications of Frolov's cubature formulae suitable for functions supported on the cube (not in the cube) which provide the same minimal worst-case error up to a constant. This constant involves the norms of a ``change of variable'' and a ``pointwise multiplication'' mapping, respectively, between the function spaces of interest. In fact, we complement, extend and improve classical results by Bykovskii, Dubinin and Temlyakov on the boundedness of change of variable mappings in Besov-Sobolev spaces of mixed smoothness. Our proof technique relies on a new characterization via integral means of mixed differences and maximal function techniques, general enough to treat Besov and Triebel-Lizorkin spaces at once. The second modification, which only tackles the case of periodic functions, is based on a pointwise multiplication and is therefore most likely more suitable for applications than the (traditional) ``change of variable'' approach. These new theoretical insights are expected to be useful for the design of new (and robust) cubature rules for multivariate functions on the cube.
description: 33 pages
ESB: a low-cost EEG Syncronization Box (project repository)
Creators: name: Bilucaglia, Marco
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medical Sciences
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Medicine and Health Sciences
subject: Electrical and Computer Engineering
subject: Engineering
subject: Biomedical Engineering and Bioengineering
subject: EEG
subject: ERP
subject: Marker
subject: Synchronization
subject: Synchronization Box
subject: Trigger

description: Project repository (including bill of materials and design files) for the paper "ESB: a low-cost EEG Syncronization Box"
D6.1 - Creation of the project website, graphical identity and other online tools
Creators: name: START Project
Publisher: name: Zenodo
Year: 2022

description: The present deliverable fulfils the requirements of demonstrating the achievement of the following objectives:
 • Creation of a graphical identity for the project.
 • Creation of the project website: www.START-HEproject.com. Also a second domain was bought (www.HE-START.eu) and automatically redirected to the main address.
 • Creation of other online tools:
 - a LinkedIn page (https://www.linkedin.com/company/start-he-project/)
 - a YouTube channel (https://www.youtube.com/channel/UCHVjEhpVz9uaEgzICj2InPA)
 - a Twitter account (https://twitter.com/START_Heproject)
 - a Twitch account (https://www.twitch.tv/start_he_project)
 - a SlideShare account (https://es.slideshare.net/StartProject/)
Endorsement Deduction and Ranking in Social Networks
Creators: name: Pérez-Rosés, Hebert
name: Sebé, Francesc
name: Ribó, Josep Maria
Publisher: name: arXiv
Year: 2015
Subjects: subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences
subject: H.3.3; H.3.4

description: Some social networks, such as LinkedIn and ResearchGate, allow user endorsements for specific skills. In this way, for each skill we get a directed graph where the nodes correspond to users' profiles and the arcs represent endorsement relations. From the number and quality of the endorsements received, an authority score can be assigned to each profile. In this paper we propose an authority score computation method that takes into account the relations existing among different skills. Our method is based on enriching the information contained in the digraph of endorsements corresponding to a specific skill, and then applying a ranking method admitting weighted digraphs, such as PageRank. We describe the method, and test it on a synthetic network of 1493 nodes, fitted with endorsements.
description: 32 pages
Additional file 1 of Individual-specific networks for prediction modelling – A scoping review of methods
Creators: name: Gregorich, Mariella
name: Melograna, Federico
name: Sunqvist, Martina
name: Michiels, Stefan
name: Van Steen, Kristel
name: Heinze, Georg
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Additional file 1. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist
Risk factors for intimate partner violence and abuse among adolescents and young adults: Extended Data
Creators: name: Herbert, Annie
name: Heron, Jon
name: Barter, Christine
name: Szilassy, Eszter
name: Barnes, Maria
name: Howe, Laura
name: Feder, Gene
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: Adolescents
subject: ALSPAC
subject: Cohort studies
subject: Dating Violence
subject: Intimate Partner Violence
subject: Young Adults

description: Supporting material for a Wellcome Open Research article which requires a registered deposit.
ALOJA: A Framework for Benchmarking and Predictive Analytics in Big Data Deployments
Creators: name: Berral, Josep Ll.
name: Poggi, Nicolas
name: Carrera, David
name: Call, Aaron
name: Reinauer, Rob
name: Green, Daron
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (cs.LG)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences
subject: C.4; I.2.6

description: This article presents the ALOJA project and its analytics tools, which leverages machine learning to interpret Big Data benchmark performance data and tuning. ALOJA is part of a long-term collaboration between BSC and Microsoft to automate the characterization of cost-effectiveness on Big Data deployments, currently focusing on Hadoop. Hadoop presents a complex run-time environment, where costs and performance depend on a large number of configuration choices. The ALOJA project has created an open, vendor-neutral repository, featuring over 40,000 Hadoop job executions and their performance details. The repository is accompanied by a test-bed and tools to deploy and evaluate the cost-effectiveness of different hardware configurations, parameters and Cloud services. Despite early success within ALOJA, a comprehensive study requires automation of modeling procedures to allow an analysis of large and resource-constrained search spaces. The predictive analytics extension, ALOJA-ML, provides an automated system allowing knowledge discovery by modeling environments from observed executions. The resulting models can forecast execution behaviors, predicting execution times for new configurations and hardware choices. That also enables model-based anomaly detection or efficient benchmark guidance by prioritizing executions. In addition, the community can benefit from ALOJA data-sets and framework to improve the design and deployment of Big Data applications.
description: Submitted to IEEE Transactions on Emerging Topics in Computing (TETC). Part of the Aloja Project. Partially funded by European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement No 639595) - HiEST Project. arXiv admin note: substantial text overlap with arXiv:1511.02030
title: Mitigation of Heavy Ion-Stimulated Gas Desorption from Accelerator Components
Creators: name: Velthaus, Verena
Publisher: name: UNSPECIFIED
Year: 2023

description: Ion-stimulated desorption is a serious problem regarding intensity limitation for heavy ion circular accelerators. Lost beam ions colliding with the wall of the beam tube trigger the release of huge amounts of gas. This leads to local pressure increases up to three orders of magnitude, which in turn enhances further beam losses. Future accelerators, such as the Facility for Antiproton and Ion Research (FAIR), are designed to deliver ion beams of highest intensities. For stable beam conditions, this requires low desorbing surfaces for beam exposed accelerator components and excellent vacuum conditions with pressures in the range of 10⁻¹² mbar. The objective of this thesis was to develop surfaces with minimal ion-stimulated desorption by testing a large variety of pretreatment methods for copper, tungsten and aluminum samples including extended ex-situ thermal annealing and different combinations of lapping, polishing, etching and milling as well as sputter cleaning with keV argon ions. In addition, coatings with TiZrV, titanium nitride and carbon were tested. Ion-stimulated desorption was determined by irradiation experiments with calcium or gold ions with 4.8 MeV/u specific energy at the UNILAC beamline M1 at the GSI Helmholtz Center for Heavy Ion Research. In addition, ion-stimulated desorption measurements with highly charged ions (Au⁷⁸⁺) of different specific energies (2, 3 and 4.8 MeV/u) were conducted at CRYRING. For all experiments, desorption was quantified by recording the pressure increase with a total pressure gauge and a quadrupole mass spectrometer. For ion-stimulated desorption, the pressure increase during irradiation is converted into a number of desorbed molecules per impacting ion, the so-called desorption yield, while in complementary thermal desorption experiments outgassing is quantified by the amount of desorbed gas per surface area (mbar∙l/cm²). As surface treatments, diamond milling and polishing turned out to be appropriate solutions. Sputter cleaning with keV argon ions also result in a clear reduction of the desorption yield. Ex-situ annealing at 400 °C for about 4 h under ultra-high vacuum conditions was identified as excellent pretreatment method to reduce ion-stimulated desorption. The low desorption is preserved even after storage in atmosphere for at least 11 months. Storage in argon is recommendable, because these samples show lower desorption compared to atmosphere storage. The fact that the low desorption persists under storage in atmosphere is a strong indication that ion-stimulated desorption is not limited to the surface, but that the bulk also plays a significant role. To prepare accelerator components with minimal outgassing, both surface and bulk properties have to be optimized.
The problem of women in Hobbes's Leviathan
Creators: name: Mitchell, Megan.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Hobbes is sometimes interpreted as a proto-feminist, in that men and women are seemingly equal in the state of nature. A few scholars have argued that men and women are equally likely to establish political society. Carole Pateman denies this latter claim and maintains that despite their equal natural abilities, women become men's servants. She argues that women are weakened by their attempts to protect their children and thus, are easily conquered by men. Against Pateman, I argue that her interpretation violates psychological egoism, an essential feature of Hobbes's understanding of human nature. I advance a weak equality reading, in which men and women are equal in prudence but men are generally stronger. Eventually, men are able to conquer women and establish male dominion through contracts. Hobbes is a proto-feminist because the subordination of women is not justified by women's natural weakness, but through contracts to which women must consent.
The relationship between quadriceps/hamstring strength and anterior tibial shear force during a jump landing task
Creators: name: Bennett, Douglas R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Objective: To evaluate relationships between Anterior Tibial Shear Force (ATSF) and eccentric quadriceps strength (QuadEcc), concentric hamstring strength (HamCon), and the QuadEcc/HamCon ratio. Design: Correlational. Setting: Research laboratory. Participants: Thirty-three healthy female recreational athletes. Main Outcome Measure(s): ATSF was measured during a landing task via inverse dynamics. QuadEcc and HamCon were assessed at 60°/s, 180°/s, and 300°/s using isokinetic dynamometry. Results: QuadEcc and HamCon were not significantly related to ATSF at any testing velocity (p > 0.05). QuadEcc/HamCon was significantly related to ATSF at 60°/s (r = 0.529, p = 0.005) and 180°/s (r = 0.556, p = 0.003). Conclusion: QuadEcc and HamCon in isolation are not significantly related to ATSF. However, when considered as a functional ratio, these strength measures are predictors of ATSF. This suggests that high QuadEcc/HamCon ratios may predispose female athletes to higher ATSF and ACL injury risk. Key Words: knee injury, ACL, torque, strength ratios
Additional file 1 of Navigating a newly diagnosed cancer through clinician-facilitated discussions of health-related patient values: a qualitative analysis
Creators: name: Lynch, Kathleen A.
name: Bernal, Camila
name: Romano, Danielle R.
name: Shin, Paul
name: Nelson, Judith E.
name: Okpako, Molly
name: Anderson, Kelley
name: Cruz, Elizabeth
name: Desai, Anjali V.
name: Klimek, Virginia M.
name: Epstein, Andrew S.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Values Summary Template.
Perceived Responsiveness as an Indicator of Attachment Security
Creators: name: Rice, TeKisha
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: A core idea of attachment theory is that security develops when attachment figures are responsive to a person’s connection needs. In adult relationships, partners can foster security by understanding and addressing what each person needs from the relationship. Individuals whose partner’s efforts to be responsive are inconsistent, inappropriate, or insufficient may develop more insecure tendencies, including attachment anxiety and attachment avoidance. Some people may feel under-benefitted in their relationship, perceiving themselves as more responsive toward their partner than the partner is in turn; others feel over-benefitted, perceiving themselves as less responsiveness to their partner than the partner is in turn. Responsiveness is optimal when a person perceives and enacts similar levels of responsiveness with respect to a partner. The current project builds on prior research suggesting possible links between attachment styles and perceptions of a partner’s responsiveness, particularly between avoidant attachment tendencies and lower responsiveness (Beck et al., 2014), and links between receiving responsive support from a partner and greater mood and felt security (Feeney, 2004). The current study aims to explain the nature of association between perceptions of one’s own and one’s partner’s responsiveness and attachment security.
Additional file 3 of Individual-specific networks for prediction modelling – A scoping review of methods
Creators: name: Gregorich, Mariella
name: Melograna, Federico
name: Sunqvist, Martina
name: Michiels, Stefan
name: Van Steen, Kristel
name: Heinze, Georg
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Additional file 3. Supplementary Material S2. Questionnaire for full-text screening
Additional file 2 of Navigating a newly diagnosed cancer through clinician-facilitated discussions of health-related patient values: a qualitative analysis
Creators: name: Lynch, Kathleen A.
name: Bernal, Camila
name: Romano, Danielle R.
name: Shin, Paul
name: Nelson, Judith E.
name: Okpako, Molly
name: Anderson, Kelley
name: Cruz, Elizabeth
name: Desai, Anjali V.
name: Klimek, Virginia M.
name: Epstein, Andrew S.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Key Thematic Constructs and Illustrative Quotes.
Tutte's invariant approach for Brownian motion reflected in the quadrant
Creators: name: Franceschi, Sandro
name: Raschel, Kilian
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We consider a Brownian motion with drift in the quarter plane with orthogonal reflection on the axes. The Laplace transform of its stationary distribution satisfies a functional equation, which is reminiscent from equations arising in the enumeration of (discrete) quadrant walks. We develop a Tutte's invariant approach to this continuous setting, and we obtain an explicit formula for the Laplace transform in terms of generalized Chebyshev polynomials.
description: 14 pages, 3 figures
The Phenomenal Variation of Jim Costa's Collection
Creators: name: van Buren, Zoe
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: This thesis explores the work of Jim Costa, a collector and restorer of 18th and 19th century handmade work tools and material culture in Summers County, West Virginia. Based on a collaborative documentary project with Jim, this thesis highlights one of his collection’s central themes of “phenomenal variation,” a term Jim uses to describe the unlimited scope and potential for human creativity as evidenced by the infinite aesthetic and pragmatic variations of the handmade. I explore Jim’s collection and restoration work as communicative practices that evoke not only historical memory, but also a more timeless concern for human nature itself. This thesis engages questions of material culture, nostalgia, collections, and laborlore, using ethnographic methodology to complicate and expand upon the question of how the past lives in the present, and how concern for old things may also be concern for ourselves and our futures.
Additional file 2 of Individual-specific networks for prediction modelling – A scoping review of methods
Creators: name: Gregorich, Mariella
name: Melograna, Federico
name: Sunqvist, Martina
name: Michiels, Stefan
name: Van Steen, Kristel
name: Heinze, Georg
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Additional file 2: Supplementary Material S1. Detailed Methods. Table S1. Keyword sets used in the search strategy across the databases for article extraction. Figure S1. Year of publication of the identified studies. Table S2. Scale of the graph-theoretical features used as candidate predictors stratified by the area of application.
THE SYNTHETIC SCAFFOLDS FOR VENTRAL HERNIA REPAIR: PERSPECTIVES FOR REGENERATIVE SURGERY. SYSTEMATIC REVIEW
Creators: name: Licari, Leo
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Life Sciences
subject: regenerative surgery

description: Ventral hernia (VH) frequently affects patients after abdominal surgery. The use of a mesh is often recommended. Different materials are described, from synthetic non-resorbable meshes to biological meshes. New generation meshes, also named scaffolds, aim to combine the advantages of both materials. The aim of this review is to provide an overview of the cytological, histological, biomechanical and clinical outcomes of the use of the newest resorbable synthetic scaffolds in VH repair, based on experimental studies in a pre-clinical setting. Methods: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and to the Assessing the Methodological Quality of Systematic Reviews (AMSTAR) guidelines. Only experimental studies were included. Outcome parameters were building technique, in-vitro cytocompatibility, in-vivo histocompatibility, biomechanical analysis, and clinical outcomes. Results: Nine articles were included. The total number of cases treated was 257. Materials analyzed included electrospun silk fibroin (SF)/poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) hybrid scaffolds, biodegradable polyester poly-ε-caprolactone (PCL) in the form of nanofibers, biodegradable mesh in poly-4-hydroxybutyrate, nanofibrous PLA scaffold with a PP material to generate a sandwich-like mesh, the collagen sponge CS group, the hybrid scaffold (HS) containing CS and poly-L-lactide (PLLA), and the hybrid scaffold (HS) + bone marrow (HSBM). Conclusions: Resorbable synthetic scaffolds are new, safe, surgical materials for the treatment or prevention of ventral hernia in animal models. Scaffolds should be tested in an contaminated surgical field for emergency use. Rigorous schematic indications for data collection are needed to improve the quality of the data in order to definitively clarify the pathway involved in inflammatory induced response.
The Influence of Psychological Distress on Baseline Concussion Measures
Creators: name: Baum, Michael
Publisher: name: University of North Carolina at Chapel Hill
Year: 2012

description: Accurate concussion baseline testing is necessary for appropriate post-injury comparisons to pre-injury measurements. The purpose of this study was to determine the influence of psychological distress on baseline concussion measures, and to examine the association between change in psychological distress and change in performance on clinical measures of concussion. We completed baseline testing and an assessment of psychological distress on 165 participants. Fifty-six participants completed the same procedure ten weeks later. One-way ANOVAs were used to examine differences in dependent variables at baseline between distress groups. Chi Square tests of independence were used to examine the association between change in distress and change in clinical measures of concussion. Significant differences existed between distress groups on verbal memory, and neurobehavioral and somatic symptom reporting. Significant associations were observed between distress and postural stability, and symptom reporting. However, when considering clinical significance, psychological distress may not be a confounding variable in concussion assessment.
Advances in Precision Calculations of Higgs Boson and Single Top Quark Production at the Large Hadron Collider
Creators: name: Juvin-Quarroz, Jérémie
Publisher: name: Karlsruher Institut für Technologie (KIT)
Year: 2023
Subjects: Top Quark
Higgs Boson
non-factorisable correction
precision calculations
LHC
charm Yukawa coupling
HL-LHC
FCC
expansion by regions

description: Since the discovery of the Higgs boson in 2012, particle physics has entered an era of precision. With the upcoming increase in luminosity of the Large Hadron Collider (LHC), we will gain access to deep and detailed insights into the behaviour of fundamental particles. On the theoretical side, the description of partonic cross sections with next-to-next-to-leading order (NNLO) accuracy in Quantum Chromodynamics (QCD) is becoming a standard. Despite the astonishing agreement between the experiments and theoretical predictions, it is clear that the Standard Model (SM) of particle physics is incomplete. One way to search for New Physics is to push the accuracy of the theoretical predictions and experimental measurements further. In this thesis, we study three problems related to precision description of Higgs boson and top quark production at the LHC. In the first part, we investigate the interference contribution between two Higgs production mechanisms in the pp → H + jetc process. This process can be used to study the Yukawa coupling of the charm quark. The interference studied in this thesis requires a helicity flip on the charm-quark line, forcing us to treat the charm quarks as massive. This requirement leads to unconventional QCD phenomena, such as the importance of soft quarks and unusual collinear factorisation. In the second part, we calculate the so-called non-factorisable corrections to t-channel single top production. These corrections arise from the crosstalk between the two fermion lines present in this process. Until now, the non-factorisable contributions to single top production have been neglected because they do not appear at next-to-leading order (NLO) and they are colour-suppressed compared to the factorisable ones. However, recent studies indicate that the factorisable corrections are relatively small at NNLO and that the non-factorisable ones can be dynamically enhanced. We compute the non-factorisable corrections and discuss their numerical impact on t-channel single top production at the LHC and the Future Circular Collider (FCC). In the third part, we consider the same type of corrections to Higgs production in weak boson fusion (WBF). Contrary to the case of t-channel single top production, an exact computation of these corrections is currently impossible. We construct an expansion of the double-virtual contribution around the forward limit of the tagging jets. It turns out that the expression of the double-virtual contribution at the next-to-leading order in the eikonal approximation can be expressed in a quite compact form.
Naturally occurring caffeic acid phenethyl ester from chestnut honey-based propolis and virtual screening towards DYRK1A
Creators: name: Arslan, Idris
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Neurodegenerative diseases (NDDs) are disorders with dysfunction and ongoing loss of neurons, glial cells and the neural networks in the brain and spinal cord. DYRK1A protein was reported to modulate to the cytoskeletal fraction in human and mouse brain, and the remaining protein is located in the cytosolic and nuclear fractions. Caffeic acid phenethyl ester (CAPE) is a natural derivative of caffeic acid and found in propolis, a bee product. In this study, we focused on isolation and characterisation of CAPE from chestnut honey-based propolis by HPLC-MS/MS technique and virtual screening of CAPE towards DYRK1A by molecular docking methods. Results revealed that CAPE might be a beneficial option to treat Alzheimer disease (AD) by suppressing DYRK1A protein.
Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni
Creators: name: Rinaldi, Gabriel
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Life Sciences

description: Background. At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni. There is a pressing need to develop a reliable functional toolkit to translate these data into new biological insights and targets for intervention. CRISPR-Cas9 was recently demonstrated for the first time in S. mansoni, to produce somatic mutations in the omega-1 (ω1) gene. Methods. We employed CRISPR-Cas9 to introduce somatic mutations in a second gene, SULT-OR, a sulfotransferase expressed in the parasitic stages of S. mansoni, in which mutations confer resistance to the drug oxamniquine. A 262-bp PCR product spanning the region targeted by the gRNA against SULT-OR was amplified, and mutations identified in it by high-throughput sequencing. Results. We found that 0.3-2.0% of aligned reads from CRISPR-Cas9-treated adult worms showed deletions spanning the predicted Cas9 cut site, compared to 0.1-0.2% for sporocysts, while deletions were extremely rare in eggs. The most common deletion observed in adults and sporocysts was a 34 bp-deletion directly upstream of the predicted cut site, but rarer deletions reaching as far as 102 bp upstream of the cut site were also detected. The CRISPR-Cas9-induced deletions, if homozygous, are predicted to cause resistance to oxamniquine by producing frameshifts, ablating SULT-OR transcription, or leading to mRNA degradation via the nonsense-mediated mRNA decay pathway. However, no SULT-OR knock down at the mRNA level was observed, presumably because the cells in which CRISPR-Cas9 did induce mutations represented a small fraction of all cells expressing SULT-OR. Conclusions. Further optimisation of CRISPR-Cas protocols for different developmental stages and particular cell types, including germline cells, will contribute to the generation of a homozygous knock-out in any gene of interest, and in particular the SULT-OR gene to derive an oxamniquine-resistant stable transgenic line.
Genetische Kartierung des Inflorenszenztyps mittels Genotyping-by-Sequencing bei Hortensie (Hydrangea macrophylla)
Creators: name: Tränkner, Conny
name: Engel, Frauke
Publisher: name: Julius-Kühn-Archiv
Year: 2017
Subjects: Ballhortensie, Tellerhortensie; next generation sequencing; Kartierung

description: Genotyping-by-Sequencing facilitates genetic mapping of the inflorescence type in Hydrangea
description: Julius-Kühn-Archiv, Nr. 457 (2017): Zweites Symposium Zierpflanzenzüchtung in Quedlinburg, 13. - 14. März 2017 - Proceedings -
Additional file 1 of The effect of personalised versus non-personalised study invitations on recruitment within the ENGAGE feasibility trial: an embedded randomised controlled recruitment trial
Creators: name: Thiblin, Ella
name: Woodford, Joanne
name: Öhman, Mattias
name: von Essen, Louise
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
Superconductivity and other phase transitions in a hybrid Bose-Fermi mixture formed by a polariton condensate and an electron system in two dimensions
Creators: name: Cotleţ, Ovidiu
name: Zeytinoǧlu, Sina
name: Sigrist, Manfred
name: Demler, Eugene
name: Imamoǧlu, Ataç
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Interacting Bose-Fermi systems play a central role in condensed matter physics. Here, we analyze a novel Bose-Fermi mixture formed by a cavity exciton-polariton condensate interacting with a two-dimensional electron system. We show that that previous predictions of superconductivity [F.P. Laussy, Phys. Rev. Lett. 10, 104 (2010)] and excitonic supersolid formation [I.A. Shelykh, Phys. Rev. Lett. 14, 105 (2010)] in this system are closely intertwined- resembling the predictions for strongly correlated electron systems such as high temperature superconductors. In stark contrast to a large majority of Bose-Fermi systems analyzed in solids and ultracold atomic gases, the renormalized interaction between the polaritons and electrons in our system is long-ranged and strongly peaked at a tunable wavevector, which can be rendered incommensurate with the Fermi momentum. We analyze the prospects for experimental observation of superconductivity and find that critical temperatures on the order of a few Kelvins can be achieved in heterostructures consisting of transition metal dichalcogenide monolayers that are embedded in an open cavity structure. All optical control of superconductivity in semiconductor heterostructures could enable the realization of new device concepts compatible with semiconductor nanotechnology. In addition the possibility to interface quantum Hall physics, superconductivity and nonequilibrium polariton condensates is likely to provide fertile ground for investigation of completely new physical phenomena.
description: 20 pages, 6 figures
Pre-registration: How does the perception of gossip affect reactions to gossip?
Creators: name: Dores Cruz, Terence
name: Testori, Martina
name: Beersma, Bianca
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Industrial and Organizational Psychology
subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: gossip

description: Theoretical background and hypotheses for a experimental vignette study on how perceptions of gossip affect reactions to gossip
Neutrinoless double electron capture
Creators: name: Kotila, J.
name: Barea, J.
name: Iachello, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Direct determination of the neutrino mass is at the present time one of the most important aims of experimental and theoretical research in nuclear and particle physics. A possible way of detection is through neutrinoless double electron capture, $0νECEC$. This process can only occur when the energy of the initial state matches precisely that of the final state. We present here a calculation of prefactors (PF) and nuclear matrix elements (NME) within the framework of the microscopic interacting boson model (IBM-2) for $^{124}$Xe, $^{152}$Gd, $^{156}$Dy, $^{164}$Er, and $^{180}$W. From PF and NME we calculate the expected half-lives and obtain results that are of the same order as those of $ 0νβ^+β^+$ decay, but considerably longer than those of $0νβ^-β^-$ decay.
Speaker Verification Systems Under Various Noise and SNR Conditions
Creators: name: Wan, Qianhui
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Speaker verification
Various noise
SNR conditions

description: In speaker verification, the mismatches between the training speech and the testing speech can greatly affect the robustness of classification algorithms, and the mismatches are mainly caused by the changes in the noise types and the signal to noise ratios. This thesis aims at finding the most robust classification methods under multi-noise and multiple signal to noise ratio conditions. Comparison of several well-known state of the art classification algorithms and features in speaker verification are made through examining the performance of small-set speaker verification system (e.g. voice lock for a family). The effect of the testing speech length is also examined. The i-vector/Probabilistic Linear Discriminant Analysis method with compensation strategies is shown to provide a stable performance for both previously seen and previously unseen noise scenarios, and a C++ implementation with online processing and multi-threading is developed for this approach.
REFERENCE EXPERIMENTS ON YOUNG CONIFERS AT WOBURN EXPERIMENTAL FARM, 1961-69 , Rothamsted Experimental Station Report for 1973 Part 2
Creators: name: BLANCHE BENZIAN And S. C. R. FREEMAN
Publisher: name: Lawes Agricultural Trust
Year: 1974
Subjects: subject: rothamsted research
subject: woburn experimental farm
subject: conifers

description: Scanned PDF of REFERENCE EXPERIMENTS ON YOUNG CONIFERS AT WOBURN EXPERIMENTAL FARM, 1961-69 , part of Rothamsted Experimental Station Report for 1973 Part 2
Cochlear Implantation for Children with Unilateral Hearing Loss
Creators: name: Park, Lisa
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Speech and Hearing Science
subject: Speech Pathology and Audiology
subject: Medicine and Health Sciences
subject: Medical Specialties
subject: Communication Sciences and Disorders
subject: Rehabilitation and Therapy
subject: Pediatrics
subject: Otolaryngology

description: The aim of this project is to evaluate the benefits of cochlear implantation in preschool and kindergarten aged children with unilateral hearing loss and compare their outcomes to a group of peers with normal hearing
The presence of caring relations in current middle and high school mathematics teachers' discourses and practices
Creators: name: Chukhin, Dmitriy
Publisher: name: University of North Carolina at Chapel Hill
Year: 2011

description: Based on Nel Noddings' writings about an ethic of caring, five teachers (two high school, two middle school, and one pre-service) were interviewed in this pilot study to help determine 1. How do teachers perceive an ethic of caring in their classrooms? Particularly, a) how do they view themselves as caring for their students, b) how do they view their students as being cared for, and c) how caring relations are important with respect to mathematics, and 2. How do teachers' perceptions of an ethic of caring influence their behavior within the classroom, including their lesson plans, projects, or interactions with their students? Semi-structured interviews were used, resulting in the emergence of five major themes: 1.) fairness, 2.) a desire for their students' well-being, 3.) a desire for their students' academic success, 4.) fostering a relationship with their students, and 5.) involvement with parents. Other topics discussed include the relation of mathematics to caring relations, character education, and the role of culture in caring relations.
Additional file 2 of The effect of personalised versus non-personalised study invitations on recruitment within the ENGAGE feasibility trial: an embedded randomised controlled recruitment trial
Creators: name: Thiblin, Ella
name: Woodford, Joanne
name: Öhman, Mattias
name: von Essen, Louise
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2.
Aesthetics of Disppearance
Creators: name: Hope, Cat
Publisher: name: Monash University
Year: 2020
Subjects: subject: 190406 Music Composition
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: The Aesthetics of DisappearanceFor lapsteel, viola, cello, double bass (or any 3 low strings), percussion, organ and subtoneFor Daryl Buckley. In memorium Paul Virilio.
You will need the Decibel ScorePlayer to perform this work (see below).
PROGRAM NOTEThis piece is in the memory of Paul Virillo, whose book Art and Fear (2003) was a huge influence on my thinking. In his 1991 book,The Aesthetics of Disappearance, Virilio tracesout the relationship of biological optics to technologies of "production of appearance." This piece tests this idea with audibility, rather than optics. Perceptual gaps createillusions of continuity, where I attempt to highlight the paradox of empiricism in acoustic science as a kind of motion without mobility," as Virllo attempts in his book with optics.
NOTE TO PERFORMERS
The majority of my compositions use scores that are read on an iPad tablet computer, using the Decibel ScorePlayer, an application available on the App Store . Any fixed media is embedded in the score, and some feature automated functions. In the case of ensemble works, multiple iPads can be networked on a LAN or over the Internet so parts can be read in a synchronised way. You should upload the score file (ending with.dsz) to your iPad from your computer via AirDrop on an Apple, or cable from a PC. Instructions on how to do this and using the Decibel ScorePlayer, more generally are included in the Application, which ships with five other scores. Thus my works have different versions of the score, as you may see above. A PDF/PNG file of the score ‘image’, a DSZ file to upload onto the iPad for performance, and for some less complex scores, a video version. Hardcopies are also available from my publisher. You can find out more about the Decibel ScorePlayer, and how to make your own scores for it, here.
PERFORMANCESPremiered at Monash University, TENOR conference, July 2019.
Supplementary document for Monocular Depth Estimation Network with Single-Pixel Depth Guidance - 6202749.pdf
Creators: name: Lee, Hongjae
name: Park, Jinbum
name: Jeong, Wooseok
name: Jung, Seung-Won
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Supplemental Document
Structural Barriers to Green and Blue Spaces: A Scoping Review Protocol
Creators: name: Nejade, Rachel
name: Grace, Daniel
name: Bowman, Leigh
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Physical Sciences and Mathematics
subject: Medicine and Health Sciences
subject: blue prescriptions
subject: blue spaces
subject: green prescriptions
subject: green spaces
subject: nature-based intervention
subject: NBI

description: Emerging evidence has demonstrated that nature-based interventions (NBIs) can improve mental and physical health. Considering that the global burden of poor mental health continues to rise, such interventions could be a cost-effective means to improve mental health, as well as serve to reconnect individuals with the natural world, thereby aiding conservation efforts. However, the effectiveness of NBIs as a prescriptive intervention is a function of access to blue and green spaces, as well as many other structural determinants. Accordingly, this scoping review will explore how structural inequalities influence the effectiveness of nature-based interventions as treatment options for mental ill health. A scoping review will be conducted to identify the barriers and facilitators associated with the utilisation of green and blue spaces. The review will follow the PRISMA-ScR guidelines, in addition to the associated Cochrane guidelines for scoping reviews. A literature search will be performed across six databases, and articles will be selected based on key inclusion/ exclusion criteria. All data will be extracted to a pre-defined charting table, and the primary outcomes will be physical and mental health. This review will better inform relevant stakeholders of the potential enablers and barriers of nature-based interventions, and thereby improve provision and implementation of NBIs as public health initiatives.
Aesthetics of Disppearance
Creators: name: Hope, Cat
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 360302
subject: Music composition and improvisation

description:
A composition for lapsteel/electric guitar, 2 low strings, 1 low wind, percussion, organ and sub toneFor Daryl Buckley. In memorium Paul Virilio.You will need the Decibel ScorePlayer to perform this work (see below).PROGRAM NOTEThis piece is in the memory of Paul Virillo, whose book Art and Fear (2003) was a huge influence on my thinking. In his 1991 book,The Aesthetics of Disappearance, Virilio traces out the relationship of biological optics to technologies of "production of appearance." This piece tests this idea with audibility, rather than optics. Perceptual gaps create illusions of continuity, where I attempt to highlight the paradox of empiricism in acoustic science as a kind of motion without mobility," as Virllo attempts in his book with optics.NOTE TO PERFORMERS
The majority of my compositions use scores that are read on an iPad tablet computer, using the Decibel ScorePlayer, an application available on the App Store . Any fixed media is embedded in the score, and some feature automated functions. In the case of ensemble works, multiple iPads can be networked on a LAN or over the Internet so parts can be read in a synchronised way. You should upload the score file (ending with.dsz) to your iPad from your computer via AirDrop on an Apple, or cable from a PC. Instructions on how to do this and using the Decibel ScorePlayer, more generally are included in the Application, which ships with five other scores.Thus my works have different versions of the score, as you may see above. A PDF/PNG file of the score ‘image’, a DSZ file to upload onto the iPad for performance, and for some less complex scores, a video version. Hardcopies are also available from my publisher. You can find out more about the Decibel ScorePlayer, and how to make your own scores for it, here.PERFORMANCESPremiered at Monash University, TENOR conference, July 2019 by ELISION and Decibel in collaboration.Elision Ensemble, August 2022, The Melbourne Recital Centre.
Stress in nurses’ caring for stroke patients and families: a mixed-method study
Creators: name: Saramago, Ines
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Other Nursing
subject: Nursing
subject: FOS: Health sciences

description: Data collected from surveys for the research article "Stress in nurses’ caring for stroke patients and families: a mixed-method study"
Point Sets with Small Integer Coordinates and with Small Convex Polygons
Creators: name: Duque, Frank
name: Fabila-Monroy, Ruy
name: Hidalgo-Toscano, Carlos
Publisher: name: arXiv
Year: 2016
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: In 1935, Erdős and Szekeres proved that every set of $n$ points in general position in the plane contains the vertices of a convex polygon of $\frac{1}{2}\log_2(n)$ vertices. In 1961, they constructed, for every positive integer $t$, a set of $n:=2^{t-2}$ points in general position in the plane, such that every convex polygon with vertices in this set has at most $\log_2(n)+1$ vertices. In this paper we show how to realize their construction in an integer grid of size $O(n^2 \log_2(n)^3)$.
Empirical Empire: Russian Geographical Explorations in the 1880s
Creators: name: Riegg, Stephen
Publisher: name: University of North Carolina at Chapel Hill
Year: 2012

description: Through the lens of empire building and the creation of knowledge about foreign others, this essay assesses explorations conducted by the Imperial Russian Geographical Society in the 1880s. Based on the reports of Russia's three most influential explorers--Nikolai Przheval'skii, Gregorii Potanin, and Nikolai Miklukho-Maklai--it illustrates how they worked to incorporate Russia into the global expansion of imperialism in the late nineteenth century. By examining some of the Geographical Society's principal expeditions beyond the periphery of the Russian Empire, the essay seeks to answer broader questions about the political and cultural significance of understanding distant peoples with whom Russians traditionally had little interaction.