cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Time-scales of close-in exoplanet radio emission variability
Creators: name: See, V.
name: Jardine, M.
name: Fares, R.
name: Donati, J. -F.
name: Moutou, C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We investigate the variability of exoplanetary radio emission using stellar magnetic maps and 3D field extrapolation techniques. We use a sample of hot Jupiter hosting stars, focusing on the HD 179949, HD 189733 and tau Boo systems. Our results indicate two time-scales over which radio emission variability may occur at magnetised hot Jupiters. The first is the synodic period of the star-planet system. The origin of variability on this time-scale is the relative motion between the planet and the interplanetary plasma that is co-rotating with the host star. The second time-scale is the length of the magnetic cycle. Variability on this time-scale is caused by evolution of the stellar field. At these systems, the magnitude of planetary radio emission is anticorrelated with the angular separation between the subplanetary point and the nearest magnetic pole. For the special case of tau Boo b, whose orbital period is tidally locked to the rotation period of its host star, variability only occurs on the time-scale of the magnetic cycle. The lack of radio variability on the synodic period at tau Boo b is not predicted by previous radio emission models, which do not account for the co-rotation of the interplanetary plasma at small distances from the star.
description: 10 pages, 7 figures, 2 tables, accepted in MNRAS
title: Ca-cough-phony: harbinger of tuberculosis
Creators: name: Pai, Vivek
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Lung
subject: Mediastinum
subject: Musculoskeletal system
subject: CT-High Resolution
subject: Education
subject: Infection

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: The purpose of this educational exhibit is to present an exhaustive compilation of thoracic tuberculosis diagnosed using computed tomography (CT). The exhibit aims at describing the pulmonary complications of tuberculosis and possible imaging...
Menopausal Hormone Therapy and Subclinical Cardiovascular Disease in Women With and Without Human Immunodeficiency Virus
Creators: name: Jackson, E.A.
name: Kaplan, R.C.
name: Hoover, D.R.
name: Tien, P.C.
name: Yin, M.T.
name: Anastos, K.
name: Levine, S.R.
name: Adimora, A.A.
name: Ofotokun, I.
name: Peters, B.A.
name: Sharma, A.
name: Michel, K.G.
name: Moran, C.A.
name: Haberlen, S.A.
name: Alcaide, M.L.
name: Hodis, H.N.
name: Hanna, D.B.
name: Cohen, M.
name: Shi, Q.
Publisher: name: Oxford University Press
Year: 2023

description: Background: Estrogen-based hormone therapy (HT) may have beneficial cardiovascular effects when initiated in early menopause. This has not been examined in women with human immunodeficiency virus (HIV), who have heightened immune activation and cardiovascular risks. Methods: Among 609 postmenopausal women (1234 person-visits) in the Women's Interagency HIV Study, we examined the relationship of ever HT use (oral, patch, or vaginal) with subclinical atherosclerosis: carotid artery intima-media thickness (CIMT), distensibility, and plaque assessed via repeated B-mode ultrasound imaging (2004-2013). We also examined associations of HT with cross-sectional biomarkers of immune activation and D-dimer. Statistical models were adjusted for sociodemographic, behavioral, and cardiometabolic factors. Results: Women (mean age, 51 years; 80% HIV positive) who ever used HT at baseline were older, and more likely to be non-Hispanic White and report higher income, than never-users. Women who ever used HT had 43% lower prevalence of plaque (prevalence ratio, 0.57 [95% confidence interval {CI},. 40-.80]; P <. 01), 2.51 μm less progression of CIMT per year (95% CI, -4.60, to -.41; P =. 02), and marginally lower incidence of plaque over approximately 7 years (risk ratio, 0.38 [95% CI,. 14-1.03; P =. 06), compared with never-users, adjusting for covariates; ever HT use was not associated with distensibility. These findings were similar for women with and without HIV. Ever HT use was associated with lower serum D-dimer, but not with biomarkers of immune activation after covariate adjustment. Conclusions: HT may confer a subclinical cardiovascular benefit in women with HIV. These results begin to fill a knowledge gap in menopausal care for women with HIV, in whom uptake of HT is very low.
Quench Dynamics of Two Coupled Ionic Zig-Zag Chains
Creators: name: Klumpp, Andrea
name: Liebchen, Benno
name: Schmelcher, Peter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: We explore the non-equilibrium dynamics of two coupled zig-zag chains of trapped ions in a double well potential. Following a quench of the potential barrier between both wells, the induced coupling between both chains due to the long-range interaction of the ions leads to their complete melting. The resulting dynamics is however not exclusively irregular but leads to phases of motion during which various ordered structures appear with ions arranged in arcs, lines and crosses. We quantify the emerging order by introducing a suitable measure and complement our analysis of the ion dynamics using a normal mode analysis showing a decisive population transfer between only a few distinguished modes.
R statistical language training workshop for IFPRI and FMARD personnel
Creators: name: Blessing, Agada
name: Hegarty, Philip
name: Blessing, Agada
name: Hegarty, Philip
Publisher: name: Unknown
Year: 2021
Subjects: subject: Agricultural and Food Policy
subject: Nigeria
subject: Training
subject: Agriculture
subject: Economics

description: An R programing language training for statistical analysis was conducted for personnel of the International Food and Policy Research Institute (IFPRI) and Ministry staff of the Federal Ministry of Agriculture and rural development (FMARD). It took place from the 27th to 29th of September 2021 at the conference room of the Fadama III House Wuse II FCT, Abuja.
(3978) Helene S McFarlane
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Biosynthesis of a reserve endopolysaccharide in the hyperthermophilic archaeon Thermococcus hydrothermalis
Creators: name: GRUYER, Sebastien
name: LEGIN, Estelle
name: BLIARD, Christophe
name: DUCHIRON, Francis
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2002

Abstract
title: Evaluating the Relationship between Incidental Non-Alcoholic Fatty Liver Disease on CT Imaging and Risk of Coronary Artery Disease
Creators: name: Bullen, Paul
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Cardiovascular system
subject: Computer applications
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Metabolic disorders

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Non-alcoholic fatty liver disease (NAFLD) is a common condition that histologically ranges from simple steatosis, steatohepatitis to advanced fibrosis. NAFLD is an increasingly common cause of chronic liver disease and affects up to 30% of the adult...
title: Rain penetration and its control
Creators: name: Garden, G. K.
Publisher: name: National Research Council of Canada. Division of Building Research
Year: 1963
Subjects: subject: Rainscreen walls
valueUri: urn:ircsubjects:IRC03821
subject: Murs à écran pare-pluie
valueUri: urn:ircsubjects:IRC03821
subject: rain penetration
subject: pénétration de la pluie
subject: walls
subject: mur
subject: rain screens
subject: écran pare-pluie

description: It is only recently that scientific studies have been undertaken to explain the mechanisms of rain penetration. Through better understanding of these mechanisms it should be possible to design and construct walls from which the problem is virtually eliminated.
Oncogenic Activity of Ect2 Is Regulated through Protein Kinase Cι-mediated Phosphorylation
Creators: name: Justilien, Verline
name: Fields, Alan P.
name: Rossman, Kent L.
name: Der, Channing J.
name: Jameison, Lee
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The Rho GTPase guanine nucleotide exchange factor Ect2 is genetically and biochemically linked to the PKCι oncogene in non-small cell lung cancer (NSCLC). Ect2 is overexpressed and mislocalized to the cytoplasm of NSCLC cells where it binds the oncogenic PKCι-Par6 complex, leading to activation of the Rac1 small GTPase. Here, we identify a previously uncharacterized phosphorylation site on Ect2, threonine 328, that serves to regulate the oncogenic activity of Ect2 in NSCLC cells. PKCι directly phosphorylates Ect2 at Thr-328 in vitro, and RNAi-mediated knockdown of either PKCι or Par6 leads to a decrease in phospho-Thr-328 Ect2, indicating that PKCι regulates Thr-328 Ect2 phosphorylation in NSCLC cells. Both wild-type Ect2 and a phosphomimetic T328D Ect2 mutant bind the PKCι-Par6 complex, activate Rac1, and restore transformed growth and invasion when expressed in NSCLC cells made deficient in endogenous Ect2 by RNAi-mediated knockdown. In contrast, a phosphorylation-deficient T328A Ect2 mutant fails to bind the PKCι-Par6 complex, activate Rac1, or restore transformation. Our data support a model in which PKCι-mediated phosphorylation regulates Ect2 binding to the oncogenic PKCι-Par6 complex thereby activating Rac1 activity and driving transformed growth and invasion.
Electrodynamics on Cosmological Scales
Creators: name: Li, Li-Xin
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Maxwell's equations cannot describe a homogeneous and isotropic universe with a uniformly distributed net charge, because the electromagnetic field tensor in such a universe must be vanishing everywhere. For a closed universe with a nonzero net charge, Maxwell's equations always fail regardless of the spacetime symmetry and the charge distribution. The two paradoxes indicate that Maxwell's equations need be modified to be applicable to the universe as a whole. We consider two types of modified Maxwell equations, both can address the paradoxes. One is the Proca-type equation which contains a photon mass term. This type of electromagnetic field equations can naturally arise from spontaneous symmetry breaking and the Higgs mechanism in quantum field theory, where photons acquire a mass by eating massless Goldstone bosons. However, photons loose their mass when symmetry is restored, and the paradoxes reappear. The other type of modified Maxwell equations, which are more attractive in our opinions, contain a term with the electromagnetic potential vector coupled to the spacetime curvature tensor. This type of electromagnetic field equations do not introduce a new dimensional parameter and return to Maxwell's equations in a flat or Ricci-flat spacetime. We show that the curvature-coupled term can naturally arise from the ambiguity in extending Maxwell's equations from a flat spacetime to a curved spacetime through the minimal substitution rule. Some consequences of the modified Maxwell equations are investigated. The results show that for reasonable parameters the modification does not affect existing experiments and observations. However, the field equations with a curvature-coupled term can be testable in astrophysical environments where mass density is high or the gravity of electromagnetic radiation plays a dominant role in dynamics, e.g., interior of neutron stars and the early universe.
description: 23 pages, including 1 figure. Version matching publication in GRG
p53-inducible DHRS3 Is an Endoplasmic Reticulum Protein Associated with Lipid Droplet Accumulation
Creators: name: Deisenroth, Chad
name: Tollini, Laura
name: Jin, Aiwen
name: Zhang, Yanping
name: Itahana, Yoko
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The transcription factor p53 plays a critical role in maintaining homeostasis as it relates to cellular growth, proliferation, and metabolism. In an effort to identify novel p53 target genes, a microarray approach was utilized to identify DHRS3 (also known as retSDR1) as a robust candidate gene. DHRS3 is a highly conserved member of the short chain alcohol dehydrogenase/reductase superfamily with a reported role in lipid and retinoid metabolism. Here, we demonstrate that DHRS3 is an endoplasmic reticulum (ER) protein that is shuttled to the ER via an N-terminal endoplasmic reticulum targeting signal. One important function of the ER is synthesis of neutral lipids that are packaged into lipid droplets whose biogenesis occurs from ER-derived membranes. DHRS3 is enriched at focal points of lipid droplet budding where it also localizes to the phospholipid monolayer of ER-derived lipid droplets. p53 promotes lipid droplet accumulation in a manner consistent with DHRS3 enrichment in the ER. As a p53 target gene, the observations of Dhrs3 location and potential function provide novel insight into an unexpected role for p53 in lipid droplet dynamics with implications in cancer cell metabolism and obesity.
title: Five year outcomes after adjuvant post prostatectomy image-guided intensity-modulated radiotherapy (IG-IMRT) using Australian guidelines
Creators: name: Chin, Stephen
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Image guided radiotherapy
subject: Cancer
subject: Radiation therapy / Oncology
subject: Intensity Modulated Radiotherapy (IMRT)
subject: Efficacy studies
subject: CT
subject: Oncology
subject: Genital / Reproductive system male
subject: Quality assurance

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Current guidelines recommend consideration of adjuvant radiotherapy (ART) after prostatectomy for high risk pathological features thought to be predictors of residual local disease such as seminal vesicle invasion, positive surgical margins or...
Visualizing the Pt doping effect on surface and electronic structure in Ir_{1-x}Pt_{x}Te_{2} by scanning tunneling microscopy and spectroscopy
Creators: name: Fujisawa, Y.
name: Machida, T.
name: Igarashi, K.
name: Kaneko, A.
name: Mochiku, T.
name: Ooi, S.
name: Tachiki, M.
name: Komori, K.
name: Hirata, K.
name: Sakata, H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report on the Pt doping effect on surface and electronic structure in Ir$_{\mathrm{1-x}}$Pt$_{\mathrm{x}}$Te$_ {\mathrm{2}}$ by scanning tunneling microscopy (STM) and spectroscopy (STS). The surface prepared by cleavage at 4.2 K shows a triangular lattice of topmost Te atoms. The compounds that undergo structural transition have supermodulation with a fixed wave vector $q = \frac{2π}{5a_m}$ (where $a_m$ is the lattice constant in the monoclinic phase) despite the different Pt concentrations. The superconducting compounds show patch structures. The surface of the compound that exhibits neither the superconductivity nor the structural transition shows no superstructure. In all doped samples, the dopant is observed as a dark spot in STM images. The tunneling spectra near the dopant show the change in the local density of state at approximately -200 mV. Such microscopic effects of the dopant give us the keys for establishing a microscopic model of this material.
description: 6 pages, 3 figures
REPRODUCTIVE ECOLOGY OF SOME NORTHERN NEW ZEALAND BRYOZOA
Creators: name: GORDON, D.P.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1970

description: The breeding seasons of 23 species of Bryozoa from Goat Island Bay, New Zealand are recorded. These species broadly show three breeding patterns; a very restricted breeding season, a year round breeding season and a season from spring to early winter. During the peak of reproductive activity almost all colonies of Fenestrulina malusii var. thyreophora above 25 mm2 in area contained embryos, and these are found in ovicells of 25 p. 100 of the zooids, on the average. The frequency of occurrence of various types of brood chamber among the cheilostomes at Goat Island Bay is recorded. Tables of substrate habitation of larvae and colours of embryos are given, and the abnormal occurrence of albino embryos in two species and its implications are discussed. Annual fluctuations in breeding activity are compared to sea water temperature and food availability and it is suggested that the latter has a more direct influence on initiation of reproduction.
title: Flame spread
Creators: name: Shorter, G. W.
Publisher: name: National Research Council of Canada. Division of Building Research
Year: 1963
Subjects: subject: flame spread
subject: propagation de la flamme
subject: fire compartments
subject: compartiment coupe feu
subject: flame spread ratings
subject: indice de propagation (flamme)
subject: building codes
subject: code du bâtiment

description: It is recognized that factors other than flammability of lining materials -- ventilation, the nature and distribution of the contents and geometry of a compartment -- can materially affect the development of a fire. When these are equal, however, fire will develop more rapidly in the compartment having the more flammable lining. The selection of materials for the interior linings of buildings is therefore an important consideration; it affects not only the safety of property but also the safety of the occupants. The hazard exists, as well, for those in other areas who may be trapped by a rapidly spreading fire.
Pheromone- and RSP5-dependent Ubiquitination of the G Protein β Subunit Ste4 in Yeast
Creators: name: Torres, Matthew P.
name: Kelley, Joshua B.
name: Dohlman, Henrik G.
name: Zhu, Ming
name: Wang, Yuqi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Ste4 is the β subunit of a heterotrimeric G protein that mediates mating responses in Saccharomyces cerevisiae. Here we show that Ste4 undergoes ubiquitination in response to pheromone stimulation. Ubiquitination of Ste4 is dependent on the E3 ligase Rsp5. Disrupting the activity of Rsp5 abolishes ubiquitination of Ste4 in vivo, and recombinant Rsp5 is capable of ubiquitinating Ste4 in vitro. We find also that Lys-340 is a major ubiquitination site on Ste4, as pheromone-induced ubiquitination of the protein is prevented when this residue is mutated to an arginine. Functionally, ubiquitination does not appear to regulate the stability of Ste4, as blocking ubiquitination has no apparent effect on either the abundance or the half-life of the protein. However, when presented with a concentration gradient of pheromone, Ste4K340R mutant cells polarize significantly faster than wild-type cells, indicating that ubiquitination limits pheromone-directed polarized growth. Together, these findings reveal a novel stimulus-dependent posttranslational modification of a Gβ subunit, establish Ste4 as a new substrate of the E3 ligase Rsp5, and demonstrate a role for G protein ubiquitination in cell polarization.
(3980) Elisabeth Sinclair
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Phosphorylation of a PDZ Domain Extension Modulates Binding Affinity and Interdomain Interactions in Postsynaptic Density-95 (PSD-95) Protein, a Membrane-associated Guanylate Kinase (MAGUK)
Creators: name: King, David S.
name: Zhang, Jun
name: Petit, Chad M.
name: Lee, Andrew L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Postsynaptic density-95 is a multidomain scaffolding protein that recruits glutamate receptors to postsynaptic sites and facilitates signal processing and connection to the cytoskeleton. It is the leading member of the membrane-associated guanylate kinase family of proteins, which are defined by the PSD-95/Discs large/ZO-1 (PDZ)-Src homology 3 (SH3)-guanylate kinase domain sequence. We used NMR to show that phosphorylation of conserved tyrosine 397, which occurs in vivo and is located in an atypical helical extension (α3), initiates a rapid equilibrium of docked and undocked conformations. Undocking reduced ligand binding affinity allosterically and weakened the interaction of PDZ3 with SH3 even though these domains are separated by a ∼25-residue linker. Additional phosphorylation at two linker sites further disrupted the interaction, implicating α3 and the linker in tuning interdomain communication. These experiments revealed a novel mode of regulation by a detachable PDZ element and offer a first glimpse at the dynamic interaction of PDZ and SH3-guanylate kinase domains in membrane-associated guanylate kinases.
title: Endovascular stenting as a therapeutic option for adult pulmonary artery stenosis
Creators: name: Maggacis, Nicole
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Interventional vascular
subject: Oncology
subject: Vascular
subject: Catheter arteriography
subject: CT
subject: Fluoroscopy
subject: Stents
subject: Outcomes

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To discuss endovascularstenting of the pulmonary arteries asa potential treatment option in cases of pulmonary artery stenosis which may occur due to a variety of conditions. We anecdotally report on the presentation, procedural details and outcome...
OGLE-IV: Fourth Phase of the Optical Gravitational Lensing Experiment
Creators: name: Udalski, A.
name: Szymański, M. K.
name: Szymański, G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present both the technical overview and main science drivers of the fourth phase of the Optical Gravitational Lensing Experiment (hereafter OGLE-IV). OGLE-IV is currently one of the largest sky variability surveys worldwide, targeting the densest stellar regions of the sky. The survey covers over 3000 square degrees in the sky and monitors regularly over a billion sources. The main targets include the inner Galactic Bulge and the Magellanic System. Their photometry spans the range of $12
description: 38 pages, 21 figures
The Hubble Space Telescope UV Legacy Survey of Galactic Globular Clusters. III. A quintuple stellar population in NGC2808
Creators: name: Milone, A. P.
name: Marino, A. F.
name: Piotto, G.
name: Renzini, A.
name: Bedin, L. R.
name: Anderson, J.
name: Cassisi, S.
name: D'Antona, F.
name: Bellini, A.
name: Jerjen, H.
name: Pietrinferni, A.
name: Ventura, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In this study we present first results from multi-wavelength Hubble Space Telescope (HST) observations of the Galactic globular cluster GC NGC2808 as an extension of the Hubble Space Telescope UV Legacy Survey of Galactic GCs (GO-13297 and previous proprietary and HST archive data). Our analysis allowed us to disclose a multiple-stellar-population phenomenon in NGC2808 even more complex than previously thought. We have separated at least five different populations along the main sequence and the red giant branch (RGB), that we name A, B, C, D and E (though an even finer subdivision may be suggested by the data). We identified the RGB bump in four out of the five RGBs. To explore the origin of this complex CMD, we have combined our multi-wavelength HST photometry with synthetic spectra, generated by assuming different chemical compositions. The comparison of observed colors with synthetic spectra suggests that the five stellar populations have different contents of light elements and helium. Specifically, if we assume that NGC2808 is homogeneous in [Fe/H] (as suggested by spectroscopy for Populations B, C, D, E, but lacking for Population A) and that population A has a primordial helium abundance, we find that populations B, C, D, E are enhanced in helium by Delta Y~0.03, 0.03, 0.08, 0.13, respectively. We obtain similar results by comparing the magnitude of the RGB bumps with models. Planned spectroscopic observations will test whether also Population A has the same metallicity, or whether its photometric differences with Population B can be ascribed to small [Fe/H] and [O/H] differences rather than to helium.
description: 49 pages, 19 figure, accepted for publication in ApJ
Phosphorylation of G Protein-coupled Receptor Kinase 1 (GRK1) Is Regulated by Light but Independent of Phototransduction in Rod Photoreceptors
Creators: name: Tserentsoodol, Nomingerel
name: Iuvone, P. Michael
name: Jo, Rebecca
name: Weiss, Ellen R.
name: Xiong, Yubin
name: Osawa, Shoji
name: Arshavsky, Vadim Y.
name: Reidel, Boris
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Phosphorylation of rhodopsin by G protein-coupled receptor kinase 1 (GRK1, or rhodopsin kinase) is critical for the deactivation of the phototransduction cascade in vertebrate photoreceptors. Based on our previous studies in vitro, we predicted that Ser21 in GRK1 would be phosphorylated by cAMP-dependent protein kinase (PKA) in vivo. Here, we report that dark-adapted, wild-type mice demonstrate significantly elevated levels of phosphorylated GRK1 compared with light-adapted animals. Based on comparatively slow half-times for phosphorylation and dephosphorylation, phosphorylation of GRK1 by PKA is likely to be involved in light and dark adaptation. In mice missing the gene for adenylyl cyclase type 1, levels of phosphorylated GRK1 were low in retinas from both dark- and light-adapted animals. These data are consistent with reports that cAMP levels are high in the dark and low in the light and also indicate that cAMP generated by adenylyl cyclase type 1 is required for phosphorylation of GRK1 on Ser21. Surprisingly, dephosphorylation was induced by light in mice missing the rod transducin α-subunit. This result indicates that phototransduction does not play a direct role in the light-dependent dephosphorylation of GRK1.
title: Many Faces of Meningiomas: Imaging Findings and Management Implications
Creators: name: Toodayan, Azhar
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: CT
subject: Oncology
subject: CNS
subject: MR
subject: Education
subject: Multidisciplinary cancer care
subject: Outcomes

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To highlight typical imaging findings of meningiomas at common sites To illustrate CT and MRI features of meningiomas at atypical sites with extension beyond the cranial vault and associated diagnostic management...
title: Thermal bridges in buildings
Creators: name: Brown, W. P.
name: Wilson, A. G.
Publisher: name: National Research Council of Canada. Division of Building Research
Year: 1963
Subjects: subject: Bridges
valueUri: urn:ircsubjects:IRC1140
subject: Ponts
valueUri: urn:ircsubjects:IRC1140
subject: Heat performance
valueUri: urn:ircsubjects:IRC0381
subject: Performance thermique
valueUri: urn:ircsubjects:IRC0381
subject: cold bridges
subject: pont thermique
subject: heat losses
subject: déperdition de chaleur

description: Walls and roofs designed today often incorporate details that have a lower resistance to heat flow than the main construction. In general, these details are thermally weak because high-conductivity structural elements project partly or wholly through materials of lower conductivity; in this Digest they are referred to as "thermal bridges". To provide a basis for recognizing and minimizing the problems presented by thermal bridges, this Digest deals with a few examples and illustrates factors that influence their thermal performance.
The Effect of Menopausal Status, Age, and Human Immunodeficiency Virus (HIV) on Non-AIDS Comorbidity Burden Among US Women
Creators: name: Golub, E.T.
name: Adimora, A.A.
name: Ofotokun, I.
name: Kassaye, S.
name: Anastos, K.
name: Sheth, A.N.
name: Mehta, C.C.
name: Tien, P.C.
name: Fischl, M.A.
name: French, A.L.
name: Palella, F.J.
name: Collins, L.F.
name: Taylor, T.N.
name: Naggie, S.
name: Fatade, Y.
name: Kempf, M.-C.
Publisher: name: Oxford University Press
Year: 2023

description: Menopause may impact the earlier onset of aging-related comorbidities among women with versus without human immunodeficiency virus (HIV). We found that menopausal status, age, and HIV were independently associated with higher comorbidity burden, and that HIV impacted burden most in the pre-/perimenopausal phases.
title: Assessment of therapeutic benefit of Hysterosalpingo-Contrast-Sonography (HyCoSy) in sub-fertile women to increase the chance of spontaneous or assisted reproductive technology pregnancies.
Creators: name: Pearce, Sarah
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Obstetrics (Pregnancy / birth / postnatal period)
subject: Ultrasound
subject: Hysterosalpingography
subject: Obstetrics

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The diagnostic accuracy of hysterosalpingo-contrast-sonography (HyCoSy) is well documented in recent studies and has the potential to replace the hysterosalpingogram as a diagnostic test due to its tolerability and efficacy. 1-5 Many studies have...
Low Temperature metamagnetism and Hall effect anomaly in Kondo compound CeAgBi2
Creators: name: Thomas, S. M.
name: Rosa, P. F. S.
name: Lee, S. B.
name: Parameswaran, S. A.
name: Fisk, Z.
name: Xia, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Heavy fermion (HF) materials exhibit a rich array of phenomena due to the strong Kondo coupling between their localized moments and itinerant electrons. A central question in their study is to understand the interplay between magnetic order and charge transport, and its role in stabilizing new quantum phases of matter. Particularly promising in this regard is a family of tetragonal intermetallic compounds Ce{$TX$}$_2$ ($T=$ transition metal, $X=$ pnictogen), that includes a variety of HF compounds showing $T$-linear electronic specific heat $\bf{C_e \sim γT}$, with $γ\sim$ 20-500 mJ$\cdot$mol$^{-1}$~K$^{-2}$, reflecting an effective mass enhancement ranging from small to modest. Here, we study the low-temperature field-tuned phase diagram of high-quality CeAgBi$_2$ using magnetometry and transport measurements. We find an antiferromagnetic transition at ${T_{N} = 6.4}$~K with weak magnetic anisotropy and the easy axis along the $c$-axis, similar to previous reports (${T_{N} = 6.1}$~K). This scenario, along with the presence of two anisotropic Ruderman-Kittel-Kasuya-Yosida (RKKY) interactions, leads to a rich field-tuned magnetic phase diagram, consisting of five metamagnetic transitions of both first and second order. In addition, we unveil an anomalous Hall contribution for fields $H<54$ kOe which is drastically altered when $H$ is tuned through a trio of transitions at 57, 78, and 84~kOe, suggesting that the Fermi surface is reconstructed in a subset of the metamagnetic transitions.
description: (*equal contribution)
An Ant Colony Optimization Algorithm for Partitioning Graphs with Supply and Demand
Creators: name: Jovanovic, Raka
name: Tuba, Milan
name: Voss, Stefan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: In this paper we focus on finding high quality solutions for the problem of maximum partitioning of graphs with supply and demand (MPGSD). There is a growing interest for the MPGSD due to its close connection to problems appearing in the field of electrical distribution systems, especially for the optimization of self-adequacy of interconnected microgrids. We propose an ant colony optimization algorithm for the problem. With the goal of further improving the algorithm we combine it with a previously developed correction procedure. In our computational experiments we evaluate the performance of the proposed algorithm on both trees and general graphs. The tests show that the method manages to find optimal solutions in more than 50% of the problem instances, and has an average relative error of less than 0.5% when compared to known optimal solutions.
Supplementary materials for: The accuracy of field classifications for journals in Scopus
Creators: name: Thelwall, Mike
name: Pinfield, Stephen
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 461005
subject: Informetrics

description: Supplementary materials for: The accuracy of field classifications for journals in ScopusS1: Software instructionsS2: Analysis of out-of-field journals for RQ3S3: Sample sizesS4 Additional research question
Positive Regulatory Domain I (PRDM1) and IRF8/PU.1 Counter-regulate MHC Class II Transactivator (CIITA) Expression during Dendritic Cell Maturation
Creators: name: Wright, Gabriela
name: Ozato, Keiko
name: Tailor, Prafullakumar
name: Wu, Jian
name: Wei, Sheng
name: Smith, Matthew A.
name: Piskurich, Janet F.
name: Wright, Kenneth L.
name: Ting, Jenny P.Y.
name: Chen, Xianghong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Dendritic cells (DCs) are key mediators of immune function through robust and tightly regulated presentation of antigen in the context of the MHC Class II. MHC Class II expression is controlled by the transactivator CIITA. CIITA expression in conventional DCs is uniquely dependent on an uncharacterized myeloid cell-specific promoter, CIITApI. We now identify in vivo the promoter structure and factors regulating CIITApI. In immature DCs transcription requires binding of PU.1, IRF8, NFκB, and Sp1 to the promoter. PU.1 binds independently at one site and in a required heterodimer with IRF8 at a composite element. DCs from IRF8-null mice have an unoccupied CIITApI promoter that can be rescued by reconstitution with IRF8 in vitro. Furthermore, mutation of either PU.1 site or the IFR8 site inhibits transcriptional activation. In vivo footprinting and chromatin immunoprecipitation reveals that DC maturation induces complete disassociation of the bound activators paralleled by recruitment of PRDM1/Blimp-1 to the promoter. PRDM1 is a transcriptional repressor with essential roles in B cells, T cells, NK cells, and DCs. We show that PRDM1 co-repressors, G9a and HDAC2, are recruited to CIITApI, leading to a loss of histone acetylation and acquisition of histone H3K9 dimethylation and heterochromatin protein 1γ (HP1γ). PRDM1 binding also blocks IRF8-mediated activation dependent on the PU.1/IRF composite element. Together these findings reveal the mechanisms regulating CIITA and, thus, antigen presentation in DCs, demonstrating that PRDM1 and IRF8/PU.1 counter-regulate expression. The activity of PRDM1 in silencing all three cell type-specific CIITA promoters places it as a central regulator of antigen presentation.
PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ
Creators: name: Liu, Chen Ying
name: Lei, Qun Ying
name: Xiong, Yue
name: Lv, Xianbo
name: Xu, Yanping
name: Guan, Kun Liang
name: Zhou, Xin
name: Li, Tingting
name: Zhao, Shimin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The Hippo pathway regulates organ size by controlling both cell proliferation and apoptosis. TAZ functions as a transcriptional co-activator downstream of the Hippo pathway and has been implicated in human cancer development. A key step in the Hippo-TAZ pathway is phosphorylation of TAZ by LATS kinase, which leads to TAZ inhibition by both cytoplasmic retention and degradation. However, the mechanism of TAZ dephosphorylation and the responsible phosphatase are unknown. Here, we identified PP1 as a bona fide TAZ phosphatase. PP1A dephosphorylates TAZ at Ser-89 and Ser-311, promotes TAZ nuclear translocation, and stabilizes TAZ by disrupting the binding to the SCF E3 ubiquitin ligase. Furthermore, ASPP2 facilitates the interaction between TAZ and PP1 to promote TAZ dephosphorylation. As a result, PP1 and ASPP2 increase TAZ-dependent gene expression. This study demonstrates that PP1A and ASPP2 play a critical role in promoting TAZ function by antagonizing the LATS kinase through TAZ dephosphorylation.
Analyses of 16S rRNA and RuBisCO large subunit genes from an abyssal low-temperature vent, Loihi Seamount, Hawaii
Creators: name: ELSAIED, Hosam E.
name: SATO, Makoto
name: NAKA, Jiro
name: NAGANUMA, Takeshi
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2002

Abstract
(3975) James Calder
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Recruitment and population structure of the vetigastropod Lepetodrilus elevatus at 13°N hydrothermal vent sites on East Pacific Rise
Creators: name: SADOSKY, Franck
name: THIEBAUT, Eric
name: JOLLIVET, Didier
name: SHILLITO, Bruce
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2002

Abstract
Jahn-Teller induced nematic orbital order in tetragonal Sr$_2$VO$_4$
Creators: name: Teyssier, J.
name: Giannini, E.
name: Stucky, A.
name: Cerný, R.
name: Eremin, M. V.
name: van der Marel, D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Using high resolution X-Ray diffraction (XRD) on high purity powders, we resolved the structure and $ab$ symmetry of the intriguing compound \svo$ $ from room temperature down to 20 K to an unprecedented level of accuracy. Upon cooling, this new set of data unambiguously reveals a second order phase transition lowering the symmetry from tetragonal to orthorhombic at a temperature $T_{c2}=136$ K. The observation of an orthorhombic distortion of the $ab$-plane is attributed to nematic phase formation supported by local Jahn-Teller (JT) dynamical instability. At $T_{N}=105$ K, spins order and at $T_{c1}=100$ K the tetragonal structure is recovered with an elongated c-axis.
description: 4 pages, 2 figures
Additional file 1 of Diagnosis of pathogens causing bacterial meningitis using Nanopore sequencing in a resource-limited setting
Creators: name: Pallerla, Srinivas Reddy
name: Van Dong, Do
name: Linh, Le Thi Kieu
name: Van Son, Trinh
name: Quyen, Dao Thanh
name: Hoan, Phan Quoc
name: Trung, Ngo Tat
name: The, Nguyen Trong
name: Rüter, Jule
name: Boutin, Sébastien
name: Nurjadi, Dennis
name: Sy, Bui Tien
name: Kremsner, Peter G.
name: Meyer, Christian G.
name: Song, Le Huu
name: Velavan, Thirumalaisamy P.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Nanopore R9.4.1 flow cell sequencing results generated from EPI2ME cloud analysis of complete fastq reads.
Electronic structure of YbB$_{6}$: Is it a Topological Insulator or not?
Creators: name: Kang, Chang-Jong
name: Denlinger, J. D.
name: Allen, J. W.
name: Min, Chul-Hee
name: Reinert, F.
name: Kang, B. Y.
name: Cho, B. K.
name: Kang, J. -S.
name: Shim, J. H.
name: Min, B. I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: To resolve the controversial issue of the topological nature of the electronic structure of YbB$_{6}$, we have made a combined study using density functional theory (DFT) and angle resolved photoemission spectroscopy (ARPES). Accurate determination of the low energy band topology in DFT requires the use of modified Becke-Johnson exchange potential incorporating the spin-orbit coupling and the on-site Coulomb interaction $U$ of Yb $4f$ electrons as large as 7 eV. We have double-checked the DFT result with the more precise GW band calculation. ARPES is done with the non-polar (110) surface termination to avoid band bending and quantum well confinement that have confused ARPES spectra taken on the polar (001) surface termination. Thereby we show definitively that YbB$_{6}$ has a topologically trivial B 2$p$-Yb 5$d$ semiconductor band gap, and hence is a non-Kondo non-topological insulator (TI). In agreement with theory, ARPES shows pure divalency for Yb and a $p$-$d$ band gap of 0.3 eV, which clearly rules out both of the previous scenarios of $f$-$d$ band inversion Kondo TI and $p$-$d$ band inversion non-Kondo TI. We have also examined the pressure-dependent electronic structure of YbB$_{6}$, and found that the high pressure phase is not a Kondo TI but a \emph{p}-\emph{d} overlap semimetal.
description: The main text is 6 pages with 4 figures, and the supplementary information contains 6 figures. 11 pages, 10 figures in total To be appeared in Phys. Rev. Lett. (Online publication is around March 16 if no delays.)
(3976) Peter McFarlane
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Nonlinear acoustic wave generation in a three-phase seabed
Creators: name: Kukarkin, A. B.
name: Pushkina, N. I.
name: Zhileikin, Ya. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Generation of an acoustic wave by two pump sound waves is studied in a three-phase marine sediment that consists of a solid frame and the pore water with air bubbles in it. To avoid shock-wave formation the interaction is considered in the frequency range where there is a significant amount of sound velocity dispersion. Nonlinear equations are obtained to describe the interaction of acoustic waves in the presence of air bubbles. An expression for the amplitude of the generated wave is obtained and numerical analysis of its dependence on distance and on the resonance frequency of bubbles is performed.
description: 10 pages, 1 fig
ANATOMIE, HISTOLOGIE ET HISTOCHIMIE DES CAECUMS RECTAUX D'ASTERIAS RUBENS L. (ÉCHINODERME, ASTÉROÏDE)
Creators: name: BOUILLON, Jean
name: JANGOUX, Michel
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1970

description: The rectal caeca of Asterias rubens L. have four tissue layers: an internal epithelium with banal and glandular cells, a connective layer, one or more muscle layers with variable bearings and a thin external epithelium.
The histochemistry of the internal epithelium shows that glandular cells are mucous cells containing mixed polysaccharids and acidic mucopolysaccharids. The banal cells of this epithelium present typical brush border, lipoproteic granules associated to neutral mucopolysaccharids, aminopeptidase granules and high concentration in alcaline phosphatases (apical region) and in acid phosphatases (basal region). The external epithelium contains both triglycerids and acid phosphatases.
Habitat reversal in vent and seep mussels: seep species, Bathymodiolus heckerae, derived from vent ancestors
Creators: name: WON, Yong-Jin
name: MAAS, Paula A. Y.
name: VAN DOVER, Cindy Lee
name: VRIJENHOEK,
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2002

Abstract
(3977) Mary J McFarlane
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(3972) Jas M Morton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.