cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A review of reviews on principles, strategies, outcomes and impacts of research partnerships approaches: a first step in synthesising the research partnership literature
Creators: name: Hoekstra, Femke
name: Mrklas, K. J.
name: Khan, M.
name: McKay, R. C.
name: Vis-Dunbar, Mathew
name: Sibley, K. M.
name: Nguyen, T.
name: Graham, I. D.
name: Gainforth, Heather
Publisher: name: BioMed Central
Year: 2020

description: Background: Conducting research in partnership with stakeholders (e.g. policy-makers, practitioners, organisations, patients) is a promising and popular approach to improving the implementation of research findings in policy and practice. This study aimed to identify the principles, strategies, outcomes and impacts reported in different types of reviews of research partnerships in order to obtain a better understanding of the scope of the research partnership literature. Methods: This review of reviews is part of a Coordinated Multicenter Team approach to synthesise the research partnership literature with five conceptually linked literature reviews. The main research question was ‘What principles, strategies, outcomes and impacts are reported in different types of research partnership approaches?’. We included articles describing a literature review of research partnerships using a systematic search strategy. We used an adapted version of the Revised Assessment of Multiple Systematic Reviews tool to assess quality. Nine electronic databases were searched from inception to April 2018. Principles, strategies, outcomes and impacts were extracted from the included reviews and analysed using direct content analysis. Results: We included 86 reviews using terms describing several research partnership approaches (e.g. community-based participatory research, participatory research, integrated knowledge translation). After the analyses, we synthesised 17 overarching principles and 11 overarching strategies and grouped them into one of the following subcategories: relationship between partners; co-production of knowledge; meaningful stakeholder engagement; capacity-building, support and resources; communication process; and ethical issues related to the collaborative research activities. Similarly, we synthesised 20 overarching outcomes and impacts on researchers, stakeholders, the community or society, and the research process. Conclusions: This review of reviews is the first that presents overarching principles, strategies, outcomes and impacts of research partnerships. This review is unique in scope as we synthesised literature across multiple research areas, involving different stakeholder groups. Our findings can be used as a first step to guide the initiation and maintenance of research partnerships and to create a classification system of the key domains of research partnerships, which may improve reporting consistency in the research partnership literature. Trial registration: This study is registered via Open Science Framework: https://doi.org/10.17605/OSF.IO/GVR7Y.
Perspectives of Significant Others in Dialysis Modality Decision-Making
Creators: name: De Rosenroll, Alexis J
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Dialysis
Decision making
Significant other

description: Objective: To understand the experiences of the dialysis decision-making process from the perspective of the significant other, specifically their role, influencing factors and the supportive interventions of the interprofessional team. Method: An interpretive description qualitative study was conducted using individual interviews and results were triangulated with decisional conflict and decisional regret quantitative results. Results: Ten participants described their role as advocating, providing a positive outlook, ‘being with’ the patient, learning together, sharing opinions, and communicating about values, preferences, feasibility of options. Environmental factors that influenced decision making included unexpected life change, choosing life, and personal health problems. Factors related to implementation of the treatment modality decision were unanticipated events, relationship changes, recreational travel changes, and the caregiver role. Nursing interventions are required to realign treatment expectations. Relevance: Significant others have an important role in supporting the patient making the dialysis decision and are often instrumental in implementing the decision.
SMEs risk management: an analysis of the existing literature considering the different risk streams
Creators: name: Brancia, Adriana
Publisher: name: Swinburne
Year: 2024

description: The analysis developed in this paper has been dedicated to the deep study of the founded papers about the risk management in SMEs and especially the comparison inside the same risk stream for evidencing the percentage of interest paid for each different risk type and the considered phase of the risk management process. At the same time have been mentioned the new practical instruments devised for SMEs for helping them in individuating the risks inside their firms by the use of simple and efficient tools.
Supplementary document for Terahertz transmissive half-wave metasurface with enhanced bandwidth - 5321532.pdf
Creators: name: You, Xiaolong
name: Ako, Rajour
name: Lee, Wendy
name: Bhaskaran, Madhu
name: Sriram, Sharath
name: Fumeaux, Christophe
name: Withayachumnankul, Withawat
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplemental Document
Entrepreneurship education: How socially focused should we be?
Creators: name: Maluwetig, Michelle
name: Verreynne, Martie-Louise
Publisher: name: Swinburne
Year: 2024

description: Even before the financial crisis, the business academia and mainstream media have called into question the relevance of a business education. The business community is facing declining trust, and employers and consumers alike are demanding a new breed of leaders and innovators. This paper presents empirical evidence that firstly, social dimensions are dominant themes in business education among high-performing universities and secondly, that this integration is statistically associated with gains in reputation and higher incomes for students after graduation. Leading universities are already accruing social and economic value by staying abreast of social innovation. These developments also have the opportunity to improve the outcomes for the broader university sector.
Centre expérimental Mhea® de M'Diq (Maroc) “Epuration des eaux usées urbaines” : Problème de communication ou incapacité d’intégration
Creators: name: Ennabili, Abdeslam
Publisher: name: figshare
Year: 2020
Subjects: subject: 90410 Water Treatment Processes
subject: FOS: Chemical engineering
subject: 90703 Environmental Technologies
subject: FOS: Environmental engineering

description: Extrait de l'Introduction:
Ce papier donne un survol sur divers aspects de ce Centre pour combler le manque chronique d‟informations précises à ce propos, et contribuer au débat sur la “volonté/capacité” de nos acteurs universitaires à valoriser in situ les acquis de la coopération internationale auprès de leurs partenaires socio-économiques
Cultivando Violetas: Vamos falar da violência contra a pessoa idosa?
Creators: name: Mass, Ana Carolina Pereira
name: Falarino, Carolina Silva
name: Silva Lima, Eliseu da Neto
name: Gimenez, Fernanda Vieira
name: Murgo, Rafael Nascimento
name: Vernasque, Juliana Ribeiro da Silva
name: Marin, Maria José Sanches
Publisher: name: Zenodo
Year: 2024
Subjects: Abuso de idosos
Saúde do idoso
Idosos
Violência
Educação em saúde

description: O livreto intitulado "Cultivando Violetas: Vamos falar da violência contra a pessoa idosa?" aborda de maneira abrangente e informativa a temática da violência contra os idosos. A cartilha tem por objetivo informar a população de modo geral, com uma abordagem facilitada para a compreensão do grande público, inclusive à população idosa.

Dividido em seções claras e concisas, o material começa explicando a escolha do nome "Violetas", uma referência ao Junho Violeta, mês de Conscientização da Violência contra a Pessoa Idosa, estabelecido pela ONU em 2006. A definição de violência contra a pessoa idosa é delineada pelo Estatuto da Pessoa Idosa, descrevendo-a como qualquer ação ou omissão que cause dano físico, psicológico, ou morte à pessoa idosa. O livreto explora diversas formas de violência, desde as mais visíveis, como a violência física e sexual, até as mais sutis, como a psicológica e a financeira.

O livreto possui a abordagem mais recente que envolve a população idosa, uma vez que durante a pandemia de Covid-19, a vulnerabilidade dos idosos à violência aumentou devido ao isolamento social. O livreto ressalta os sinais de abuso, tanto físicos quanto emocionais, comportamentais, sexuais e financeiros, que podem indicar a ocorrência de violência contra os idosos.

Além disso, são discutidas as barreiras que impedem as vítimas de denunciarem os abusos, como o medo de represálias e o sentimento de culpa. As consequências para os agressores também são abordadas, destacando as penalidades previstas pelo Estatuto da Pessoa Idosa para os diversos tipos de abuso.

O material também destaca os direitos da pessoa idosa garantidos pelo Estatuto, incluindo o direito à vida, saúde, alimentação, educação, entre outros. Por fim, ressalta a importância da valorização da pessoa idosa na sociedade, destacando a necessidade de políticas públicas e ações que promovam o respeito, dignidade e autonomia dos idosos.
Diplomacia científica
Creators: name: Ordoñez Matamoros, Héctor Gonzalo
name: Caro Vargas, Soraya Stella
name: Aya Smitmans, María Teresa
name: Piñeros Ayala, Rafael Enrique
Publisher: name: Universidad Externado de Colombia
Year: 2022

description: Este curso profundiza en las relaciones entre la diplomacia y el ámbito científico, tecnológico y de innovación, reconociéndolos como pilares esenciales para la construcción de consensos políticos sólidos, el desarrollo de estrategias efectivas y la implementación de políticas públicas de éxito. Además de analizar estas conexiones, el curso explora detalladamente cómo estas áreas colaboran en la resolución de desafíos a distintos niveles, ya sea a escala global, regional, nacional o local, fomentando la cooperación entre actores tanto del sector público como del privado.
Introducción a la economía de mercado - MOOC
Creators: name: Herrera Saavedra, Juan Pablo
Publisher: name: Universidad Externado de Colombia
Year: 2022

description: Objetivos generales: Dar a conocer el funcionamiento de los mercados, sus componentes y la forma como se relacionan. Objetivos específicos: * Introducir conceptos básicos del funcionamiento de un mercado, sus componentes y la forma como se relacionan. * Introducir el concepto de elasticidad y sus implicaciones en el modelo básico de oferta y demanda. * Introducir los conceptos básicos que constituyen los determinantes de los excedentes del consumidor y el productor.
description: En este curso tendremos la oportunidad de entender qué es un mercado y su relevancia dentro del análisis económico. De esta manera, exploraremos cómo funcionan los mercados y de qué manera las transacciones que se llevan a cabo, podrían generar la distribución eficiente de los recursos entre vendedores y compradores. Igualmente, tendremos la oportunidad de presentar algunas herramientas que nos permitan explicar los límites y los alcances de la forma en que opera una economía de mercado.
Electivas técnicas y especializadas en neurociencia social
Creators: name: Corredor Silva, Dana Kamila
Publisher: name: Universidad Externado de Colombia
Year: 2022

description: Objetivos generales: Abrir un espacio que le permita a los estudiantes fortalecer sus conocimientos y habilidades en el desarrollo de proyectos de generación del conocimiento. Objetivos específicos; * Revisar los conceptos fundamentales ligados al estudio de los comportamientos complejos y su modelación. * Brindar las herramientas teóricas y prácticas para el procesamiento y el análisis de la información cualitativa de distinto tipo (texto, audio, video, imágenes, bases de datos, redes sociales, entre otros), así como capacitar a los estudiantes en el manejo de software como NVivo y Atlas.ti, diseñados para el acompañamiento en estas fases de sus investigaciones. * Discutir y aportar conocimientos históricos, teóricos y epistemológicos necesarios para entender los conceptos de la neurociencia tradicional y cómo estos son usados como fundamento para la neurociencia social desde un punto de vista técnico electrofisiológico.
description: El curso se centra en las técnicas de la neurociencia social en las que se realizará un trayecto del análisis y las herramientas que nos ayudarán a entender los conceptos que se hablarán en este curso. Se iniciará viendo las aproximaciones y los abordajes desde la complejidad, un procesamiento y análisis de la información cualitativa, y los registros electrofisiológicos de la neurociencia social. Además, se realizarán diseños experimentales en neurociencia, pruebas psicométricas y unos registros observacionales en neurociencia que le permitirá a los estudiantes tener un mejor conocimiento para el desarrollo de proyectos de generación del conocimiento.
Interpretación económico-legal del daño en inversiones
Creators: name: Álvarez Zarate, José Manuel
Publisher: name: Universidad Externado de Colombia
Year: 2022

description: Objetivos generales: Brindar las herramientas para la interpretación de tratados internacionales y emplear las metodologías existentes para la valoración de los daños en un arbitraje internacional. Objetivos específicos * Dar a conocer las formas de interpretación existente para las normas aplicables. * Brindar información sobre las metodologías más utilizadas para el cálculo-valoración de los daños.
description: Este curso contiene un panorama general del derecho económico internacional en inversiones, que será complementado con la interpretación de los tratados internacionales de inversión, el daño en las inversiones y los activos de los inversionistas, por medio del análisis de los requisitos del daño resarcible, el principio de reparación y las formas de reparación del daño. También, se aprenderá sobre la expropiación y la compensación o indemnización de los principios aplicables a esta y en torno a otro tipo de violaciones, finalmente se socializará sobre el valor justo del mercado y las metodologías para su determinación, reducciones y diferentes tipos de activos.
The Role of SirT1 in Resveratrol Toxicity
Creators: name: Morin, Katy
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: SirT1
resveratrol
toxicity
cancer
embryonic stem cells
MEFs

description: SirT1 is a class III histone deacetylase that has beneficial roles in various diseases related to aging such as cancer, diabetes and neurodegenerative disease. Resveratrol is a natural compound that mimics most of the beneficial effects attributed to SirT1. Resveratrol has toxicity towards cancer cells and has been reported to be a direct activator of SirT1. Interestingly, SirT1 over-expression has also been reported to be toxic. We set out to determine if resveratrol toxicity is mediated through activation of SirT1. We have assessed resveratrol toxicity in embryonic stem cells and mouse embryonic fibroblast (MEFs) across different SirT1 genotypes. Our data indicates that SirT1 is not implicated in resveratrol toxicity in either normal or transformed MEFs. Thus, resveratrol toxicity does not appear to be mediated by SirT1.
title: Mitteilungen des Kunsthistorischen Institutes in Florenz, Bd. 53 Nr. 1 (2009): Mitteilungen des Kunsthistorischen Institutes in Florenz
title: Mitteilungen des Kunsthistorischen Institutes in Florenz
titleType: AlternativeTitle
Creators: name: Mitteilungen Des Kunsthistorischen Institutes In Florenz
Publisher: name: Mitteilungen des Kunsthistorischen Institutes in Florenz
Year: 2018

description: Band LIII (2009), Heft 1
description: The True Identity of the Anonimo Magliabechiano...157-168
Il Recupero di un Autografo del Botticelli...150-156
Il Ritratto "Caricato in Forma Strana, i Ridicolosa, e con Tanta Felicità di Somiglianza". La Nascita della Caricatura e i suoi Sviluppi in Italia Fino al Settecento...73-144
Curso para auxiliares de investigación - CIPE
Creators: name: Vargas. Paola
name: Harte, Marie
Publisher: name: Universidad Externado de Colombia
Year: 2022

description: Objetivos generales: Fortalecer las habilidades de investigación de los auxiliares de investigación mediante los conocimientos, las técnicas y las prácticas efectivas. Objetivos específicos: Resultados de aprendizaje + Identificar las principales acciones que determinan las buenas prácticas en la etapa hermenéutica, en particular con las actividades de apoyo en la recolección de la información. * Fortaler sus habilidades para identificar y recolectar las fuentes de información académicas y periodísticas confiables. * Diferenciar y manejar las herramientas digitales y las diferentes bases de datos para una búsqueda y una recuperación eficiente de la información.
description: Este curso se encuentra orientado a la identificación de problemas y la proposición de soluciones desde la academia; por ende, niciará con una revisión bibliográfica que se logrará con el conocimiento de la ética de la investigación, la consulta de las bases de datos, las revisiones de prensa y la sistematización de las fuentes bibliográficas. Además, se tratará el apoyo en espacios académicos que se realizará con la elaboración de las actas, las memorias de trabajo y la técnica de toma de apuntes; por último, los productos de investigación que serán apoyados con la transcripción de entrevistas, consejos, consultas, uso de base de datos y redacción de resúmenes.
Striving Towards an Understanding of Experienced Teachers’ Perceptions of the Usefulness, Ease of Use and Effective Integration of Technology in their Classroom
Creators: name: Faw, Kieran
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Narrative Theory
Teachers
Perceptions
Technology
Integration
Limits
Strategies
Resources
Perceived Usefulness
Perceived Ease of Use

description: This thesis uses Narrative Theory and Technology Acceptance Model to uncover the experiences, perceptions, and challenges that five experienced teachers face when using and integrating technology in their classroom. It gives narrative consideration of the value of unique experience by focusing on the stories of each participant, and it analyzes narrative themes. This study found that there were numerous impacts on teachers’ perceptions on the usefulness and ease of use of technology: this included (a) Limits: technology limits, teacher limits, student limits, and practical limits; (b) Support: school board, resources, equipment, parents; and (c) Dynamic environment (teacher-student feedback loop) which influence strategies for integrating technology: attitude, teaching orientation, classroom management, technology management, technology tools, and participant-observer strategies. Study limitations and recommendations are discussed.
Diplomado Habilidades gerenciales para la reactivación, la sostenibilidad y la paz - Córdoba y Antioquia
Creators: name: Gutiérrez Yepes, Paula Andrea
name: Zarama Salazar, Felipe
name: Chavarro Mayusa, María Paula
name: Contreras, Luisa
name: Mosquera Ángulo, Tatiana
name: Méndez Lacorazza, María Lucía
name: Yepes Mejía, Alejandro
name: Quevedo Gualteros, Carolina
name: Rojas Gómez, Santiago
name: Vargas González, Paola Andrea
name: Marín, Isabela
name: Camacho Murillo, Giovanni Andrés
name: Sánchez Garzón, Mary Sol
name: Vélez Llanos, Nosliu Zeley
name: De La Cuesta Zuluaga, Luisa
Publisher: name: Universidad Externado de Colombia
Year: 2022

description: Objetivos generales: Fortalecer las capacidades de los empresarios para lograr una reactivación económica que aporte a la transformación territorial, a la equidad de género y a la sostenibilidad en regiones de alta afectación por el conflicto armado. Objetivos específicos: * Entender el contexto económico, político y social a nivel nacional, regional y local que permitan al empresario tomar decisiones informadas. * Maximizar el impacto de las empresas y potenciar su liderazgo en clave de sostenibilidad, construcción de paz y transformación del territorio. * Hacer más sostenibles y fortalecer los negocios.
description: En este módulo se abordará un análisis detallado del entorno económico regional, la reactivación económica y las comunicaciones de liderazgo. Además, se explorará el fortalecimiento del rol de los empresarios para la transformación del territorio en clave de paz y sostenibilidad, acompañado de temas como: las empresas, su construcción de paz y desarrollo sostenible; la equidad de género para esta actividad y la sostenibilidad e inclusión social; por último, se hablará sobre las brechas de los DDHH y la paz para la actividad empresarial, la definición del modelo de negocio e implementación y medición.
Dyslexic and entrepreneur: typologies, commonalities and differences
Creators: name: Franks, Karen
name: Frederick, Howard
Publisher: name: Swinburne
Year: 2024

description: There is anecdotal evidence as well as a small but growing research literature indicating there may be a higher incidence of dyslexia amongst entrepreneurs compared to business managers and to the general population. Studies indicate that while dyslexics may resist entry into mainstream businesses due to their generally low literacy levels, there appears to be no such barrier for dyslexics wanting to start new ventures. Given that dyslexics also dislike imposed structure, have strong oral and spatial skills, are intuitive/insightful/curious as well as resilient and determined, it is not surprising that they gravitate toward self-employment as opposed to highly organised corporate professions.
Oviductal Extracellular Vesicles Improve Post-Thaw Sperm Function in Red Wolves and Cheetahs
Creators: name: De Almeida Monteiro Melo Ferraz, Marcia
name: Nagashima, Jennifer Beth
name: Noonan, Michael J.
name: Crosier, Adrienne E.
name: Songsasen, Nucharin
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2020

description: Artificial insemination (AI) is a valuable tool for ex situ wildlife conservation, allowing the re-infusion and dissemination of genetic material, even after death of the donor. However, the application of AI to species conservation is still limited, due mainly to the poor survival of cryopreserved sperm. Recent work demonstrated that oviductal extracellular vesicles (oEVs) improved cat sperm motility and reduced premature acrosomal exocytosis. Here, we build on these findings by describing the protein content of dog and cat oEVs and investigating whether the incubation of cryopreserved red wolf and cheetah sperm with oEVs during thawing improves sperm function. Both red wolf and cheetah sperm thawed with dog and cat oEVs, respectively, had more intact acrosomes than the non-EV controls. Moreover, red wolf sperm thawed in the presence of dog oEVs better maintained sperm motility over time (>15%) though such an improvement was not observed in cheetah sperm. Our work demonstrates that dog and cat oEVs carry proteins important for sperm function and improve post-thaw motility and/or acrosome integrity of red wolf and cheetah sperm in vitro. The findings show how oEVs can be a valuable tool for improving the success of AI with cryopreserved sperm in threatened species.
title: Assessing the use of places of worship through a social resilience framework: an empirical study of managing disaster risks in Barangay San Andres, Cainta, Philippines
Creators: name: Ong, John John
Publisher: name: University of Reading
Year: 2022

description: Understanding the influence of places of worship in managing disasters is an 
important discourse in urban environment research. With the considerable presence of 
informal settlements in cities, this study analyses the resilience and social capacities of 
vulnerable communities in the informal built environment. This study aids academicians, 
professional practitioners, and government officials in determining the significance of places 
of worship in enhancing their contribution to social resilience. 
The focus of the study is situated in the informal settlements at Barangay San Andres 
in Cainta, Rizal, Philippines: a community along the riverbank of the Manggahan floodway 
that is prone to extreme weather events and disaster risks. This study examines how places 
of worship are used as a social infrastructure through the social resilience framework. 
Through a sequential exploratory research design, the qualitative data from 16 key informant 
interviews highlighted six (6) emerging themes of social resilience. A survey from 409 
respondents revealed the significance and positive effects of resilience in most social
dimensions except for social equity. Moreover, the structural equation modelling equation 
has determined that the relationships between the dimensions of social resilience to be non-linear. The framework also found social capital to have the highest influence or impact on the 
other components among all the social resilience dimensions.
The study thus presented a unique integrated social resilience framework as a 
method of assessing places of worship through a social resilience context. The study also 
provided additional insights to three religious/spiritual aspects of places of worship, namely 
(1) the spiritual space, (2) the spiritual capital, and (3) the spiritual beliefs. Hence, this study 
has introduced an integrated and transdisciplinary analysis across the social infrastructure, 
the social resilience, and the religious dimensions of places of worship.
The Transcriptional Repressor CC2D1A/Freud-1 Interacts with the Chromatin Remodeling Protein Brg1
Creators: name: Mirédin, Kim
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: CC2D1A
Freud-1

description: The serotonin-1A (5-HT1A) receptor plays an important role in the regulation of the serotonin (5-HT) system as an autoreceptor on 5-HT neurons. The transcription factor CC2D1A/Freud-1 is a potent repressor of the 5-HT1A promoter in neuronal but not in non-neuronal cells. The clinical relevance of Freud-1 is evident in a naturally occurring mutation, resulting in a truncated form of Freud-1 lacking its C-terminal half, that is associated with non syndromic mental retardation in humans. Thus, it is of interest to clarify the structure and function of Freud-1. As Freud-1 was shown to interact with the transcriptional regulator Brg1 at the 5-HT1A promoter, identification of the structural domains mediating the Brg1/Freud-1 interaction is required to assess the role of Brg1 in Freud-1 repression. In this study, I used pull-down assays with recombinant proteins, co-immunoprecipitation studies and immunofluorescent staining with confocal microscopy to show that Freud-1 interacts directly with the C-terminus of Brg1 and that the C-terminal domain of Freud-1 is required for this interaction.
Umweltbundesamt-Chef Messner: CO2-Preis für Kühe "folgerichtige Idee"
Creators: name: Kockerols, Konstantin
Publisher: name: My University
Year: 2022

description: Angesichts tierischer Emissionen hält UBA-Chef Messner einen CO2-Preis für Kühe für eine folgerichtige Idee. Konzentrieren sollte man sich jedoch auf die Reduktion der Tierzahlen in Deutschland. Quelle: https://www.topagrar.com/
Vietnamese Australian police officers: social judgements and identity constructions by other officers
Creators: name: McKernan, Helen
Publisher: name: Swinburne
Year: 2024

description: The paper explores the construction of identities of police officers with Vietnamese Australian heritage by three types of Anglo officers -- advocates, antagonists and ambivalent officers. The idea of cultural fix-points is utilised to investigate how conflict, bias and loyalty affect group identity constructions. The paper draws on data from the four-year ARC Linkage Project: Exploring the experience of security in the Australian Vietnamese community: practical implications for policing which commenced in July 2008 and concluded in 2011.The paper is based on 54 interviews with Anglo police officers in three Police Service Areas in Melbourne. The paper investigates the motivations and processes that lead to the ascription of particular identities to Vietnamese Australian officers by Anglo officers. The paper concludes with some implications for practice.
C16ORF70/Mytho promotes healthy aging in C. elegans and prevents cellular senescence in mammals.
Creators: name: Franco-Romero, Anais
name: Morbidoni, Valeria
name: Milan, Giulia
name: Sartori, Roberta
name: Wulff, Jesper
name: Romanello, Vanina
name: Armani, Andrea
name: Salviati, Leonardo
name: Conte, Maria
name: Salvioli, Stefano
name: Franceschi, Claudio
name: Buonomo, Viviana
name: Swoboda, Casey O
name: Grumati, Paolo
name: Pannone, Luca
name: Martinelli, Simone
name: Jefferies, Harold BJ
name: Dikic, Ivan
name: Van der Laan, Jennifer
name: Cabreiro, Filipe
name: Millay, Douglas P
name: Tooze, Sharon A
name: Trevisson, Eva
name: Sandri, Marco
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Signalling & Oncogenes
subject: Signalling & Oncogenes
classificationCode: Chemical Biology & High Throughput
subject: Chemical Biology & High Throughput
classificationCode: Model organisms
subject: Model organisms
classificationCode: Biochemistry & Proteomics
subject: Biochemistry & Proteomics
classificationCode: Cell Biology
subject: Cell Biology
classificationCode: Imaging
subject: Imaging

description: The identification of genes that confer either extension of lifespan or accelerate age-related decline was a step forward in understanding the mechanisms of ageing and revealed that it is partially controlled by genetics and transcriptional programs. Here we discovered that the human DNA sequence C16ORF70 encoded for a protein, named MYTHO (Macroautophagy and YouTH Optimizer), which controls life- and health-span. MYTHO protein is conserved from C. elegans to humans and its mRNA was upregulated in aged mice and elderly people. Deletion of the ortholog myt-1 gene in C. elegans dramatically shortened lifespan and decreased animal survival upon exposure to oxidative stress. Mechanistically, MYTHO is required for autophagy likely because it acts as a scaffold that binds WIPI2 and BCAS3 to recruit and assemble the conjugation system at the phagophore, the nascent autophagosome. We conclude that MYTHO is a transcriptionally regulated initiator of autophagy that is central in promoting stress resistance and healthy ageing.
Végétation ripicole et gestion des eaux de surface, cas du bassin versant de l’oued Inaouène (NO du Maroc)
Creators: name: Libiad, Mohamed
name: Abdelmajid Khabbach
name: Ennabili, Abdeslam
Publisher: name: figshare
Year: 2020
Subjects: subject: Botany
subject: 60204 Freshwater Ecology
subject: FOS: Biological sciences
subject: 60310 Plant Systematics and Taxonomy

description: Riparian vegetation and management of surface water, the case of the Inaouène-Wadi watershed (NW Morocco). Integrated management of water resources interfere, directly or indirectly, with the biodiversity conservation. In Morocco, most studies on plant diversity of wetland interested especially ecological and functioning aspects. In this work, we tried to establish a relationship between human activities (planning, pollution …) and wetland flora and its conservation status. The specific plant diversity (Spermatophyta and Pteridophyta) of the Inaouène River was estimated based on the riparian flora exploration of 21 stations. The main ecological and anthropogenic factors (sampling, planning …) affecting plant groups were discussed as elements interfering with the rivers management. The study highlights the dependence of the population vis-à-vis plant resources, which may have a negative impact on surface water, and more rational measures should be taken, namely the plantation of the native wetland plants and particularly maintaining an ecological flow in the downstream side the Idriss 1st dam.
Investigating the Performance of Wood Portal Frames as Alternative Bracing Systems in Light-Frame Wood Buildings
Creators: name: Al Mamun, Abdullah
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Portal Frame
Alternative Bracing System
Lateral Bracing System
Light-Wood Building
Corner Joint Test
FRP
Finite Element Model

description: Light-frame shearwall assemblies have been successfully used to resist gravity and lateral loads, such as earthquake and wind, for many decades. However, there is a need for maintaining the structural integrity of such buildings even when large openings in walls are introduced. Wood portal frame systems have been identified as a potential alternative to meet some aspects of this construction demand. The overarching goal of the research is to develop wood portal frame bracing systems, which can be used as an alternative or in combination with light-frame wood shearwalls. This is done through investigating the behavior of wood portal frames using the MIDPLY shearwall framing technique. A total of 21 MIDPLY corner joint tests were conducted with varying bracing details. Also, a finite element model was developed and compared with test results from the current study as well as studies by others. It was concluded from the corner joint tests that the maximum moment resistance increased with the addition of metal straps or exterior sheathings. The test results also showed a significant increase in the moment capacity and rotational stiffness by replacing the Spruce-Pine Fir (SPF), header with the Laminated Veneer Lumber (LVL) header. The addition of the FRP to the standard wall configuration also resulted in a significant increase in the moment capacity. However, no significant effect was observed on the stiffness properties of the corner joint. The FE model was capable of predicting the behavior of the corner joints and the full-scale portal frames with realistic end-conditions. The model closely predicted the ultimate lateral capacity for all the configurations but more uncertainty was found in predicting the initial stiffness.The FE model used to estimate the behavior of the full-scale portal frames constructed using the MIDPLY framing techniques showed a significant increase in the lateral load carrying capacity when compared with the traditional portal frame. It was also predicted using the full-scale FE model that the lateral load carrying capacity of the MIDPLY portal frame would increase with the addition of the metal straps on exterior faces. A parametric study showed that using a Laminated Strand Lumber (LSL) header increased the lateral load carrying capacity and the initial stiffness of the frames relative to the SPF header. The study also showed that there was an increase in the capacity if high strength metal straps were used. Doubling of the nail spacing at header and braced wall segment had a considerable effect on the lateral capacity of portal frame. Also, the initial stiffness was reduced for all the configurations with the doubling of the nail spacing at the header and braced wall segment in comparison with the reference frame.
CLEWs: A Pathway to Greener Agriculture in Tamil Nadu
Creators: name: Lakshminarayanan, Balaji
Publisher: name: Zenodo
Year: 2024
Subjects: subject: CLEWs
subject: WEF Nexus
subject: Water management

description: This study examines the effects of transitioning to Renewable Energy (RE) and upgrading the irrigation system with solar pumps in Tamil Nadu, India, focusing on the climate, land, energy, and water sectors. Using the CLEWs framework and the OSeMOSYS tool, three scenarios were analyzed: Business As Usual (BAU), RE Transition, and RE Transition with Solar Pumps. The study evaluates their impacts on emissions, land use, and water demand.

 

The results indicate that the RE Transition scenario, which relies on renewable energy, results in the lowest emissions and water usage. Additionally, replacing diesel and electric pumps with solar pumps can significantly cut CO2 emissions by 20 million tonnes per year and 44.5 billion cubic meters of water are conserved. The study highlights the value of CLEWs NEXUS modelling for ensuring sustainable and renewable energy solutions in irrigation.

 

Recommendations include integrating water and land management strategies into energy planning, prioritizing investments in renewable energy with minimal water and land impacts, and exploring various technologies to address energy and climate needs while reducing carbon emissions and environmental effects.
Supplementary document for Light recycling in LED-pumped Ce:YAG luminescent concentrators - 5321995.pdf
Creators: name: Pichon, Pierre
name: NOURRY-MARTIN, Maxime
name: Darbon, Stephane
name: Druon, Frederic
name: Balembois, Francois
name: Georges, Patrick
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Service quality, segmentation and casino player retention
Creators: name: Prentice, Catherine
Publisher: name: Swinburne
Year: 2024

description: Competition is intense between casinos within the Asia-Pacific region and this creates pressure for casinos to implement strategies which can build competitive advantage. Building and maintaining service quality is one means of retaining customers and thus establishing competitive advantage. To achieve an appropriate balance between using resources efficiently and maximising customer profitability, some casinos have established a system of segmenting players by tier. Conducted in Asia, the current study investigated the relationship between casino service quality, player segments and customer retention using tiered segmentation. The results provide insights into how the various tiers of casino player perceive the key dimensions of service quality and how such perceptions affect future purchase intentions. A number of significant implications are identified for casino managers.
Organic Template-Assisted Synthesis & Characterization of Active Materials for Li-ion Batteries
Creators: name: Yim, Chae-Ho
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Li-ion battery
template assisted synthesis
LiFePO4
SnO2
hybrid pulse power characterization
3DOM

description: The Lithium-ion (Li-ion) battery is one of the major topics currently studied as a potential way to help in reducing greenhouse gas emissions. Major car manufacturers are interested in adapting the Li-ion battery in the power trains of Plug-in Hybrid Electric Vehicles (PHEV) to improve fuel efficiency. Materials currently used for Li-ion batteries are LiCoO2 (LCO) and graphite—the first materials successfully integrated by Sony into Li-ion batteries. However, due to the high cost and polluting effect of cobalt (Co), and the low volumetric capacity of graphite, new materials are being sought out. LiFePO4 (LFP) and SnO2 are both good alternatives for the cathode and anode materials in Li-ion batteries. But, to create high-performance batteries, nano-sized carbon-coated particles of LFP and SnO2 are required. The present work attempts to develop a new synthesis method for these materials: organic template-assisted synthesis for three-dimensionally ordered macroporous (3DOM) LFP and porous SnO2. With the newly developed synthesis, highly pure materials were successfully synthesized and tested in Li-ion batteries. The obtained capacity for LFP was 158m Ah/g, which is equivalent to 93% of the theoretical capacity. The obtained capacity for SnO2 was 700 mAh/g, which is equivalent to 90% of the theoretical capacity. Moreover, Hybrid Pulse Power Characterization (HPPC) was used to test LFP and LCO for comparison and feasibility in PHEVs. HPPC is generally used to test the feasibility and capacity fade for PHEVs. It simulates battery use in various driving conditions of PHEVs to study pulse energy consumption and regeneration. In this case, HPPC was conducted on a half-cell battery for the first time to study the phenomena on a single active material, LFP or LCO. Based on the HPPC results, LFP proved to be more practical for use in PHEVs.
Enteroviral and herpes simplex virus central nervous system infections in infants < 90 days old: a Paediatric Investigators’ Collaborative Network on Infections in Canada (PICNIC) study
Creators: name: Petel, Dara
name: Barton, Michelle
name: Renaud, Christian
name: Ouchenir, Lynda
name: Brophy, Jason
name: Bowes, Jennifer
name: Khan, Sarah
name: Bitnun, Ari
name: McDonald, Jane
name: Boisvert, Andrée-Anne
name: Ting, Joseph
name: Roberts, Ashley
name: Robinson, Joan L
Publisher: name: BioMed Central
Year: 2020

description: Background: The relative contribution of viruses to central nervous system (CNS) infections in young infants is not clear. For viral CNS infections, there are limited data on features that suggest HSV etiology or on predictors of unfavorable outcome. Methods: In this cross-sectional retrospective study, seven centers from the Pediatric Investigators Collaborative Network on Infections in Canada identified infants < 90 days of age with CNS infection proven to be due to enterovirus (EV) or herpes simplex virus (HSV) January 1, 2013 through December 31, 2014. Results: Of 174 CNS infections with a proven etiology, EV accounted for 103 (59%) and HSV for 7 (4%). All HSV cases and 41 (40%) EV cases presented before 21 days of age. Four HSV cases (57%) and 5 EV cases (5%) had seizures. Three (43%) HSV and 23 (23%) EV cases lacked cerebrospinal fluid (CSF) pleocytosis. HSV cases were more likely to require ICU admission (p = 0.010), present with seizures (p = 0.031) and have extra-CNS disease (p < 0.001). Unfavorable outcome occurred in 12 cases (11% of all EV and HSV infections) but was more likely following HSV than EV infection (4 (57%) versus 8 (8%); p = 0.002). Conclusions: Viruses accounted for approximately two-thirds of proven CNS infections in the first 90 days of life. Empiric therapy for HSV should be considered in suspected CNS infections in the first 21 days even in the absence of CSF pleocytosis unless CSF parameters are suggestive of bacterial meningitis. Neurodevelopmental follow-up should be considered in infants whose course of illness is complicated by seizures.
Privacy-Preserving Data Integration in Public Health Surveillance
Creators: name: Hu, Jun
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Privacy
Security
Data Integration
Business to Business
B2B
Record Linkage
De-identification
Public Health Surveillance
Identity Linking

description: With widespread use of the Internet, data is often shared between organizations in B2B health care networks. Integrating data across all sources in a health care network would be useful to public health surveillance and provide a complete view of how the overall network is performing. Because of the lack of standardization for a common data model across organizations, matching identities between different locations in order to link and aggregate records is difficult. Moreover, privacy legislation controls the use of personal information, and health care data is very sensitive in nature so the protection of data privacy and prevention of personal health information leaks is more important than ever. Throughout the process of integrating data sets from different organizations, consent (explicitly or implicitly) and/or permission to use must be in place, data sets must be de-identified, and identity must be protected. Furthermore, one must ensure that combining data sets from different data sources into a single consolidated data set does not create data that may be potentially re-identified even when only summary data records are created. In this thesis, we propose new privacy preserving data integration protocols for public health surveillance, identify a set of privacy preserving data integration patterns, and propose a supporting framework that combines a methodology and architecture with which to implement these protocols in practice. Our work is validated with two real world case studies that were developed in partnership with two different public health surveillance organizations.
Environmental guidelines for operation of Remotely Piloted Aircraft Systems (RPAS): Experience from Antarctica
Creators: name: Harris, Colin H.
name: Herata, Heike
name: Hertel, Fritz
Publisher: name: My University
Year: 2019
Subjects: Störfall
Umweltauswirkung
Politik
Antarktis

description: Remotely Piloted Aircraft Systems (RPAS), or drones, are increasingly being used in close proximity to wildlife. RPAS can disturb animals in their natural environment, potentially causing stress or harm. However, research on the potential impact of RPAS on wildlife is preliminary and remains poorly understood. RPAS offer many benefits for research applications and other purposes, and can also help reduce wildlife disturbance that might otherwise occur. The Antarctic Treaty Parties recognised a need to develop environmental guidelines for RPAS use as a means to help avoid and/or reduce disturbance to wildlife in Antarctica while allowing for their beneficial use. To do so, a framework based on the Pressure - State - Response model was developed to provide a systematic means to consider relevant influences on RPAS and wildlife interactions. This framework was used as an aid to draft comprehensive environmental guidelines for RPAS use in Antarctica, which were adopted by the Antarctic Treaty Parties in 2018. The guidelines include recommendations for pre-flight preparations, on-site and in-flight protocols, and for post-flight actions and reporting. The guidelines were based on examples developed elsewhere in the world, on available scientific evidence for environmental impacts from RPAS, and through consultation among governments and scientific and technical bodies operating in Antarctica. The environmental guidelines adopted for RPAS operations in Antarctica could provide a model for application elsewhere in the world where there is a need to manage interactions between RPAS and wildlife and to avoid or reduce potential impacts. © 2019 Elsevier Ltd. All rights reserved
Social Barriers to Physical Activity for Individuals with Physical Disabilities
Creators: name: Cappe, Shauna
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Physical Disability
Health Promotion
Discourse
Medical Model
Social Model
Critical Disability Studies
Stakeholders
End-Users

description: The purpose of this thesis was to explore socially constructed discursive barriers to physical activity for people with physical disabilities. This research was informed by a critical disability studies framework. Eight interviews were conducted, split between end-users and stakeholders. The end-user article discusses their perspectives with regard to their own PA participation, their use of PA resources, and their views of how disability is constructed. The stakeholder article deals with their views with regard to Canada’s progress in creating inclusive PA guidelines, the research process as it effects people with physical disabilities, and how disability is constructed. The results showed awareness among both groups of the social model of disability, but that the medical model is still firmly rooted. Work is needed to create inclusive promotional materials and disseminate them effectively. An effective advocacy and lobbying effort was suggested as one avenue towards a possible solution to this issue.
Supplementary document for Light recycling in LED-pumped Ce:YAG luminescent concentrators - 5321995.pdf
Creators: name: Pichon, Pierre
name: NOURRY-MARTIN, Maxime
name: Darbon, Stephane
name: Druon, Frederic
name: Balembois, Francois
name: Georges, Patrick
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplement 1