cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Characterisation of three essential protein kinases in Trypanosoma brucei reveals they are required for cytokinesis
Creators: name: De La Torre Olvera, Helena Maritza
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Trypanosoma brucei, cell cycle, cytokinesis, kinases.

description: Trypanosoma brucei is a protozoan parasite that causes Human African Trypanosomiasis (HAT), also known as sleeping sickness and Animal African Trypanosomiasis (AAT) or nagana in livestock, which results in major health and economic burdens in Sub-Saharan Africa. Although possible treatments are available, they possess several disadvantages as toxicity, high costs of the drugs, difficulty in administration and the development of drug resistance by the parasites complicate timely treatment. The life cycle of the parasite is complex, involving a mammalian host and an insect vector (tsetse fly, Glossina spp.). A previous RNAi screen (Jones et al., 2014) of the protein kinome of the bloodstream form (BSF) of T. brucei identified 24 putative cell cycle regulators as playing a key role in the cell cycle of the parasite in vitro. From these candidates, TbKKT10, TbMAPK6, TbULK, TbCAMK, TbAEK1 and TbMAK kinases were potentially involved in cytokinesis and chosen for further analysis using a combination of an inducible RNAi silencing system, overexpression and kinase activity-dead mutants. Here, more detailed analysis reveals that TbMAK, TbCAMK and TbAEK1 are essential for cytokinesis, while TbKKT10, TbMAPK6, TbULK are essential for proliferation of the parasite, but do not play a role in cytokinesis. Depletion of TbCAMK or TbAEK1 led to inhibition of cell division, while depletion of TbMAK blocked the initiation of cytokinesis furrowing. Inducible overexpression of TbMAK6myc (but not TbAEK16myc or TbCAMK6myc) was lethal due to defective cytokinesis. Catalytically inactive kinases were generated by altering the ATP binding site, replacing the invariant lysine with methionine. Overexpression of catalytically inactive TbMAK(K33M)6myc abrogated the deleterious effects of overexpressing wild type TbMAK6myc, arguing that excess TbMAK activity is toxic to the cell and that expression of TbMAK is tightly regulated in wild type cells. Overexpression of catalytically inactive TbCAMK6myc or TbAEK16myc had no effect on cell proliferation. Moreover, analysis of immunoprecipitated TbMAK revealed that the kinase phosphorylates the generic kinase substrates, myelin basic protein and histone H1, but not α- or β-casein and is capable of autophosphorylating. Immunoprecipitated TbCAMK was able to autophosphorylate and phosphorylate myelin basic protein, α- or β-casein and histone H1. Additionally, preliminary mass spectrometry of TbMAK12myc immunoprecipitates indicate that TbMAK interacts with, and may potentially phosphorylate, various cytoskeletal proteins, thereby suggesting a putative mode of action for this kinase.
title: Conscious states during dreamless sleep: a philosophical and psychological exploration
Creators: name: Alcaraz Sánchez, Adriana
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Dreamless sleep, phenomenal consciousness, Indian philosophy.

description: Deep sleep has traditionally been deemed as a period that lack consciousness. However, recent evidence challenges this assumption and highlights the possibility of experiencing awareness during deep sleep. By drawing from Indian philosophical traditions, this thesis defends a positive view of consciousness during dreamless sleep – the period of sleep where we are aware but not dreaming. Moreover, this thesis also challenges classic views on the nature of conscious states where consciousness is reduced to representational content. For that purpose, this thesis develops a taxonomy of dreamless sleep that, contrary to other research in the area, considers the existence of different sorts of awareness with different degrees of content. Thus, a full spectrum of mental states during conscious dreamless sleep are considered: from awareness of substantial content to awareness devoid of content altogether. The aim of the thesis is to show how such a taxonomy can encourage a shift from a two-dimensional view of consciousness to a multidimensional one — from a view that only considers brain activation and reportable content to one that assesses conscious states on different level of analysis. This shift will result in an adequate conceptualisation of dreamless sleep as a period where we could have conscious states with content, but also, conscious states without content. Moreover, this shift on a multidimensional approach will allow us to undertake a proper comparison compare between different sleep phenomena. In order to develop this taxonomy of dreamless sleep, I explore definitions on awareness during dreamless sleep found in Indian philosophical traditions and Western analytical philosophy. From the definitions found in the literature, I argue that all the types of conscious states proposed in my taxonomy can be identified. Then, I test my taxonomy in a pilot study about awareness during deep sleep that I carried out. The results show that the different types of awareness can be recognised in the phenomenological descriptions gathered from the participants. Finally, I compare the phenomenon of dreamless sleep with other associated experiences, such as dreams and hypnagogia. My claim is that the differences among sleep phenomena are gradual and that in some cases there is not a strict cut-off line between them. Notwithstanding this assumption, I defend the development of future research were my proposed taxonomy can be improved by considering typical cases of dreamless sleep.
title: A mixed methods study of the relationship between illness perceptions and the cascade genetic screening process in hypertophic cardiomyopathy, and clinical research portfolio
Creators: name: Irvine, Bruce
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Illness perceptions, hypertrophic cardiomyopathy.

description: Background: Hypertrophic Cardiomyopathy (HCM) a relatively common inherited cardiac disease, symptoms include breathlessness, palpitations, chest pain and more rarely, sudden cardiac death. Cascade genetic screening where individuals already diagnosed with HCM are tasked with communicating genetic risk to relatives is an increasingly viable means of confirming HCM associated gene carriers and identifying their at-risk relatives, however uptake of such testing is suboptimal. The common-sense model of illness perceptions has frequently been used to understand behaviours linked to health within individuals (Leventhal et al., 1980). Less is understood about how these perceptions may influence communication of health information to others. Aims: The primary aim of the study was to explore whether illness perceptions of those who first undergo genetic testing for the HCM gene mutation predict uptake of cascade genetic screening by at-risk first-degree relatives. Methods: A mixed method, single centre, cross-sectional design was employed. Fifty-seven individuals with HCM undergoing genetic testing completed measures of illness perceptions, closeness to relatives and perceived self-efficacy. Data on uptake of cascade screening by respective first-degree relatives was obtained from the host clinic. Semi-structured interviews were conducted on a sub-group of six individual focusing on those who had low associated illness identity. Transcripts were explored using Thematic Analysis (TA). Results: Overall first-degree relative uptake within the sample was 65%. A linear regression indicated that relatives of individuals who perceived HCM to be a more acute condition were 13% more likely to have undergone genetic screening. Thematic analyses of interview transcripts yielded three superordinate themes: The confusing HCM experience, the reasons for testing and doubts about testing. Conclusions: The findings of this study should be considered with caution due to the limits placed on the analysis as a result of the small sample recruited. However, the findings of the analysis indicating a link between the illness perceptions of the individual tasked with communicating risk to relatives and subsequent relative uptake merits further investigation.
Teaching Heroes – Accounts of their Personal and Professional Approaches to Teaching
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 160506 Education Policy
subject: FOS: Political science
subject: Education
subject: 130103 Higher Education
subject: FOS: Educational sciences

description: This Forum Insight paper summarises key findings from a piece of qualitative research undertaken by the National Forum to explore the personal and professional approaches to teaching of the first group of Teaching Heroes (2014).
Digital Learning: Myths and Reality
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: As part of the report, Teaching and learning in Irish Higher Education: A Roadmap for Enhancement in a Digital World 2015-2017, this forum insight looks at some of the myths and reality of digital learning.
title: Data‑driven prediction of the surface layer state in hard‑turning for optimization of component quality
Creators: name: Wittich, Felix
name: Wegener, Thomas
name: Liehr, Alexander
name: Zinn, Wolfgang
name: Niendorf, Thomas
name: Kroll, Andreas
Publisher: name: Universität Kassel
Year: 2024
Subjects: subject: Surface integrity
subject: Data-driven modeling
subject: Hard-turning
subject: Residual stress
subject: 620
subject: Oberfläche
subject: Modellierung
subject: Integrität
subject: Stress

description: Gefördert im Rahmen des Projekts DEAL
Inverse probability weighted Bayesian dynamic borrowing for estimation of marginal treatment effects with application to hybrid control arm oncology studies
Creators: name: Psioda, Matthew A.
name: Bean, Nathan W.
name: Wright, Brielle A.
name: Lu, Yuelin
name: Mantero, Alejandro
name: Majumdar, Antara
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: We propose an approach for constructing and evaluating the performance of inverse probability weighted robust mixture priors (IPW-RMP) which are applied to the parameters in treatment group-specific marginal models. Our framework allows practitioners to systematically study the robustness of Bayesian dynamic borrowing using the IPW-RMP to enhance the efficiency of inferences on marginal treatment effects (e.g. marginal risk difference) in a target study being planned. A key assumption motivating our work is that the data generation processes for the target study and external data source (e.g. historical study) will not be the same, likely having different distributions for key prognostic factors and possibly different outcome distributions even for individuals who have identical prognostic factors (e.g. different outcome model parameters). We demonstrate the approach using simulation studies based on both binary and time-to-event outcomes, and via a case study based on actual clinical trial data for a solid tumor cancer program. Our simulation results show that when the distribution of risk factors does in fact differ, the IPW-RMP provides improved performance compared to a standard RMP (e.g. increased power and reduced bias of the posterior mean point estimator) with essentially no loss of performance when the risk factor distributions do not differ. Thus, the IPW-RMP can safely be used in any situation where a standard RMP is appropriate.
title: Regulation of protein import by a thioredoxin reductive pathway in the intermembrane space of mitochondria
Creators: name: Cárdenas Rodríguez, Mauricio
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Mitochondria biogenesis, import, MIA pathway, redox regulation, thioredoxin sysyem, reducing, oxidation.

description: Mitochondria are organelles that fulfil main roles in cellular metabolism. From the total mitochondrial proteome, 99% of proteins are encoded in the nucleus and have to be imported into mitochondria. Hence, mitochondria have developed at least five import pathways to drive those proteins into the four mitochondrial compartments (the outer and inner membranes, the matrix and the mitochondrial intermembrane space (IMS)). The main pathways are the presequence pathway, the carrier pathway, the β-barrel pathway, the insertion of α-helical proteins and the oxidative folding (MIA) pathway. MIA pathway imports most proteins residing in the IMS by inserting disulfide bridges onto characteristic cysteine motifs in the incoming reduced protein precursors. The import through the MIA pathway depends on the redox homeostasis of the compartments where it takes place, the cytosol and the IMS. This redox homeostasis is the balance between the oxidative and reductive pathways. In particular, the main reductive pathways are the glutaredoxin (Grx) and thioredoxin (Trx) systems, both of which share NADPH as their final electron donor. Despite extensive knowledge on the oxidative pathway, a reducing mechanism in the IMS is yet to be discovered. In this work, we studied the molecular and mechanistic aspects of redox perturbations on the MIA pathway. We found that reductive impairment in the yeast cell specifically decreased the import through the MIA pathway because the key effector, Mia40 is in an unbalanced redox state towards its oxidising form. Furthermore, based on the recent discovery of cytosolic Trx system residing also in the mitochondrial IMS, we investigate its role as this unknown reductive system in this compartment. We found that Trx interacts with Mia 40 and restores its redox state to a functional balanced oxidising and reducing state and that this partially recovers the import capacity of this yeast strain. We conclude by proposing a model in which redox state of Mia40 acts as a sensor of the import of MIA substrates in a Trx-dependent manner.
title: Underwater optical communication systems
Creators: name: Giuliano, Giovanni
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Underwater optical communication, free-space optical communication, ocean optics.

description: I present in this thesis the results of my research in the field of underwater optical communication system (UOCS). Recently, underwater free-space optical (FSO) communication has been one of the major interesting research subjects due to the high demand for underwater activities that require high-bandwidth and flexible solutions. An optical communication system consists of three main blocks: transmitter, medium and receiver. Therefore, I provide an introduction to the topic, outlining the physical reasons and the engineering challenges that are behind the following sections. Among others, the optical properties of ocean water, the optimum wavelength selection and a description of the main system components are provided so that the system link budget can be subsequently optimised. Various modulation schemes adopted in free-space optics communication are evaluated and compared with a focus on the most power-efficient modulation format that offers successful and reliable data transmission. The system performances are numerically investigated using statistical analysis techniques over a typical range of achievable SNR in an underwater scenario. The characterisation and the data performance of a commercial GaN-based laser diode operating at 450 nm are presented. The detrimental impact of the solar background power on the system performance and the strategy to minimise its contribution is also discussed for a conventional Silicon PIN detector and the novel Silicon PhotoMultiplier (SiPM) technology. The design trade-off between the performance improvement given by an optical narrow bandpass filter matching a Fraunhofer line and the field-of-view of the receiver is also presented. A flexible MATLAB model has been developed to simulate a range of different scenarios and evaluate the system performances in different situations and the necessary design trade-off. A novel free-space waveguiding method is also presented for laser-based underwater communication systems. The proposed Underwater Wireless Acousto-Optic Waveguide (UWAOW) generates a localised modification of the refractive index of seawater in response to an acoustic field. Two geometries and their modelling are provided in order to take advantage of the proposed technique. These results show the importance of this emerging, challenging and fascinating contemporary research field.
title: Reading and understanding built environments in Quebec (Canada): Urban morphology at the service of a sustainable urban design approach
Creators: name: Racine, François
Publisher: name: Conference Proceedings XXIX International Seminar on Urban Form ISUF 2022 Urban Redevelopment and Revitalisation A Multidisciplinary Perspective/Lodz University of Technology Press
Year: 2023
Subjects: Urban form, Urban morphology, Urban design, Quebec, Canada.

description: This paper is aimed to present a book about the physical and spatial organization of villages, cities, and agglomerations of the territory of the province of Quebec, located in Canada. It will be of particular interest to people who intervene, exercise a professional practice or study in the fields of architecture, landscape architecture, urban planning, urban geography, heritage, and urban design. In addition to presenting the key notions of urban morphology opening the way to an in-depth understanding of the mode of structuring of human settlements, the book explains and applies, with the help of several case studies, the methods of analysis of this field of research to read and characterize the built environments of Quebec. Finally, examples show how morphological knowledge can be operationalized in intervention strategies and urban design projects at multiple scales. At a time when the crisis of climate change urges us to deeply rethink our ways of inhabiting and practicing the territory, it is essential to better understand the product of our collective experience in these matters. Why not draw useful lessons from this to feed the work of planning, design and management of the quality and integrity of our built environment?
Development of Planning-Stage Crash Prediction Tools
Creators: name: Duong, Vu Xuan Quynh
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 400512
subject: Transport engineering
classificationCode: 4611
subject: Machine learning

description: A thesis submitted in total fulfilment of the requirements for the degree of Master of Engineering to the School of Computing, Engineering and Mathematical Sciences, La Trobe University, Victoria, Australia.
Portfolio material to support training for target groups at all Research Infrastructures (RIs)
Creators: name: Gonzalez-Beltran, Alejandra
name: Minotti, Carlo
name: Chado, Idrissou
name: Krahl, Rolf Krahl
Publisher: name: Zenodo
Year: 2022
Subjects: Photon and Neutron
Training
Target Groups
Research Infrastructures
Data Curators
PaN Domain Researcher
Ontologies

description: We present the deliverable achieved for a Portfolio material to support training for target groups at all RIs. The work represents the achievement of deliverable D3.4 of the Horizon 2020 ExPaNDS project.
description: This deliverable is not yet approved by the European Commission.
description: {"references": ["Richter, Tobias et al. Common search API definition. (2020)"]}
SocratesEffect + SOM
Creators: name: Huynh, Alex
name: Grossmann, Igor
name: Santos, Henri C.
Publisher: name: OSF Registries
Year: 2017
Subjects: Developmental
Generativity
Political discourse
Politics
Reasoning
Self-investment
Socrates
Teaching
Wisdom

description: Socrates, renowned for his wisdom, is often credited as one of the founders of modern pedagogy. One of the chief reasons for this reputation comes from Socrates’ approach to teaching. Whereas his contemporaries – Sophists – taught didactically, aiming to convince others of their opinions on issues, Socrates preferred a more integrative approach, engaging in discourse that was divest from his own personal opinions, and involving inquiries from multiple perspectives. Over centuries, scholars like Rousseau, Montessori, and Vygotsky have debated the impact of different teaching styles on students, overlooking the impact that teaching others might actually have on the teachers themselves. For example, how do people spontaneously reason when asked to teach others? Are humans intuitive Sophists or Socrateans? What factors influence people’s reasoning when teaching others? Here we investigate these questions across two experiments by asking people to explain contentious political issues to less knowledgeable others. Study 1 took place during the 2012 U.S. presidential elections, demonstrating that adopting a teaching mindset, compared to deliberating on the political issue (control condition) encourages a reasoning style that aligns with Socratic ideals – i.e., reasoning that acknowledges and integrates diverse perspectives (inclusive reasoning from here on). A pre-registered Study 2 conducted during the 2016 U.S. presidential elections demonstrates that adopting a teaching mindset also results in more inclusive reasoning, compared to explaining the same issue to a peer (control condition). Furthermore, Study 2 highlights that low self-investment, together with high generative motivations (i.e., a desire to nurture and guide others) functions as an underlying mechanism for promoting more inclusive reasoning. Additional tests ruled out other cognitive, affective, and motivational processes as potential mechanisms.
MOESM1 of Woody forages effect the intestinal bacteria diversity of golden pompano Trachinotus ovatus
Creators: name: Chen, Biao
name: Gao, Liu-ling
name: Pan, Qing
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 1. Additional table.
КИБЕРТОВЛАМАЧИЛИК УЧУН ЖИНОИЙ ЖАВОБГАРЛИКНИНГ АЙРИМ МАСАЛАЛАРИ
Creators: name: Эргашев Илёс Ўрол ўғли, Тошкент давлат юридик университети мустақил изланувчиси
Publisher: name: Zenodo
Year: 2024

description: Мазкур ишда муаллиф Ўзбекистон Республикаси Жиноят кодексининг 165-моддаси (Товламачилик) 1-қисми  диспозициясига киритилган ўзгартириш, яъни жабрланувчининг ахборот ресурсини йўқ қилиш, ўзгартириш, эгаллаб олиш ёки тўсиб қўйиш билан қўрқитган ҳолда товламачилик қилишнинг айрим ўзига ҳосликларини ўрганган.

Калит сўзлар: ахборот ресурси, товламачи дастур, кибертовламачилик, DDоS-ҳужум.
title: 02_1118
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: Parliament and prayer book: the theology and ecclesiology behind the Prayer Book Crisis
Creators: name: Cruickshank, Dan
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Theology, church history, liturgy, liturgical history, twentieth-century history, British history, English history, historical theology, ecclesiology.

description: This thesis considers the doctrinal and ecclesiological trends that were present during the construction of the revised Book of Common Prayer of 1927. Through the use of the records of both Convocations and of the National/Church Assembly, it looks at the discussions that took place within the Church of England during the construction of the revised Book. By analysing these debates, it considers the doctrinal shifts that were taking place within the Church of England after the ritual controversies of the nineteenth century. Focussing on the Communion service and the reservation of the elements for the communion of the sick, the thesis shows how much of what had been seen as ritualist had become part of the ‘mainstream’ of the Church. It challenges the idea that the revision process stalled in the First World War both by demonstrating how the process continued at the same pace during the war as it had done pre-1914, but also by showing how the birth of the National Assembly that took place during the war was born out of the revision process and a desire to avoid Parliamentary scrutiny of any revision. This will also demonstrate how the revision process created an atmosphere in which many in the Church of England had serious discussions about radically altering the ecclesiology of the Church, specifically in the area of Church-State relations. It will link into my previous work on the growth of ‘Two Kingdoms’ theology in the Church by showing how the revision process made many decide the State, in Parliament, should not have the right to debate and approve the liturgy of the Church of England. Examining the revision process in the National Assembly it will show the growth of lay power in the Church through the integral role they played in the revision process in the 1920s. Through the parliamentary debates, it will show how Parliament reasserted its right to decide the liturgy and doctrine of the Church of England, at the same time as many within the Church had decided they did not have that right. Finally it will examine how the rejection of the revised Books of 1927 and 1928 led to radical ecclesiological thinking within the Church, with many from the very top of the hierarchy advocating forms of disestablishment.
title: A system in ruins; the Victorian asylums of Britain
Creators: name: Cromey, James Martin
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Asylum, Britain, mental healthcare, historical, medicine, industrial archaeology, historical geography.

description: Despite its closure prior to the beginning of the 21st century, echoes of the county and district asylum system still remain across Britain. These grand architectural monoliths housed hundreds of people in various sites at their peak, across the countryside of England, Ireland, Scotland and Wales, and offered care to mental health patients for over a century. Despite this, many will know the asylum complexes from whistle-blower accounts or newspaper articles declaring them unfit for purpose and highlighting incidents where negligence was commonplace. Furthermore, the fictional renditions of asylums in films, novels and video games has resulted in a lingering disparity between the asylums’ heritage, and the history as more commonly depicted and digested by the public. The cultural perception of asylums is such that the sites now act as a focal point for perceived wrongdoing in past mental health care. Consequently, the sites retain a negative ambiance, brought about by the stigma shown towards these vast institutions, now lying derelict. This thesis will focus on the architecture of the asylum buildings, which will allow a discussion in to the stigma of asylums and the extent to which it is unfounded, instead based on the fictional portrayal of the asylum sites, and not the institutions themselves.
Dinuclear organotin building blocks and their conversion into a tetranuclear macrocycle containing Sn-O-Sn linkages
Creators: name: Gómez-Jaimes, Gelen
name: Rojas León, Irán
name: Martínez Romero, Rodolfo
name: Beltrán, Hiram I.
name: Rodríguez-Molina, Braulio
name: Hiller, Wolf
name: Jurkschat, Klaus
name: Hernández, Irán F.
name: Höpfl, Herbert
Publisher: name: TU Dortmund
Year: 2021
Subjects: subject: Organotin compounds
subject: Metalla-macrocyclic chemistry
subject: DOSY NMR spectroscopy
subject: X-ray diffraction analysis
subject: Self-assembly with dinuclear building block (tecton)
subject: 540

description: Six dinuclear organotin building blocks of general composition RR′R′′SnCH2Si(CH3)2−biphenyl−Si(CH3)2CH2SnR′′R′R, in which the tin atoms are separated by a p,p′-biphenylene bridge and carry different substituents [BD1 with R, R′=CH2Si(CH3)3, R′′=Ph; BD2 with R, R′=CH2Si(CH3)3, R′′=Cl; BD3, with R, R′=CH2Si(CH3)3, R′′=I; BD4 with R=CH2Si(CH3)2(C5H4FeCp), R′, R′′=Ph; BD5 with R=CH2Si(CH3)2(C5H4FeCp), R′=Ph, R”=Cl; BD6 with R=CH2Si(CH3)2(C5H4FeCp), R′=Ph, R′′=I], were synthesized and characterized by spectroscopic and spectrometric methods. Furthermore, the crystal and molecular structures of BD2 were determined by single-crystal X-ray diffraction (SCXRD) analysis, revealing the formation of molecular strands through intermolecular Cl→Sn contacts. The 1D coordination polymer [BD2]n comprises macrocyclic rings of composition [BD2]2 that motivated the generation of a related molecular macrocyclic structure by reaction of BD2 with silver (I) oxide in a 2 : 2 stoichiometry. The [2+2] macrocyclization yielded the 30-membered tetra-nuclear ring structure M1, viz., {[R2SnCH2Si(CH3)2−biphenyl−(CH3)2SiCH2SnR2](μ-O)}2, in which two BD2 dinuclear building blocks are linked through two covalent Sn−O−Sn moieties. Examination by DFT calculations at the B3LYP/def2svp and B3LYP/6-31G*(C,H,O,Si)/LanL2DZ(Sn) levels of theory gave energy minima for molecular conformers of M1 carrying the Sn−O−Sn and p,p′-biphenylene bridges in syn- or anti-orientation.
description: Eur. J. Inorg. Chem.;2021(22)
Year 1 Feedback Project
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: This Forum Insight is both timely and relevant as the scope and form of the new enhancement theme, Assessment of/for/ as Learning is being delineated. The attention of this Insight centres on the area of feedback in the first year arising from recent findings of the Teaching & Learning Enhancement funded project
Some Key European and National Teaching and Learning Policy and Practice Documents
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: This Forum Insight presents a summary of some of the key European and national teaching and learning documents (see summary table overleaf) which can be used to encourage on-going dialogue and to inform teaching and learning enhancement within the context of wider drivers and issues.
Virtual Clothing Try On
Creators: name: R, Deeraj
name: Joel Raj P, Jeffrin
name: R, Madhan Kumar
name: Haran S, Hari
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460306
subject: Image processing
classificationCode: 460308
subject: Pattern recognition

description: The VC-Try On Net is an innovative technology that addresses the limitations of existing virtual try-on applications. It provides a more effective and efficient way of trying on clothes without requiring a clean product image. The complexity of clothing items, the variety of textures, and the differences in body shapes have been significant challenges in the development of virtual try-on applications. However, through the use of the pose alignment network, the texture refinement network, and the fitting network, the VC-Try On Net has been able to overcome these challenges. Virtual clothing try-on applications serve not only to visualize garments but also to collect valuable data on customer preferences and sizes, enabling retailers to offer more personalized recommendations, inform product development decisions, and facilitate customization opportunities. By analyzing trends in customer preferences, retailers can enhance the shopping experience, increase customer satisfaction, and drive sales through tailored offerings and unique, customized products that resonate with individual styles and preferences..
REPORT: Transition from Further Education and Training to Higher Education
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: The first enhancement theme of the National Forum focused on transitions into and through higher education. Based on surveys and interviews with FET students, the research summarised in this insight begins to fill an important gap in our understanding of transitions, and it recognises the often substantially different experiences of those entering higher education from school, and those entering from the FET sector.
ENHANCEMENT THEME: Assessment OF, FOR and AS Learning: Continuing the Debate and Creating a Focus
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: Assessment OF, FOR and AS Learning is the National Forum’s enhancement theme for 2016- 2018. The National Seminar Series 2015-2016 has already facilitated some initial conversations on this theme. Feedback captured at the National Summit for the Enhancement of Teaching and Learning in Higher Education 2015 highlighted the significant changes to assessment practices and policies that could be driven by this enhancement theme.
title: The dual nature of properties: the powerful qualities view reconsidered
Creators: name: Giannotti, Joaquim
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Metaphysics of properties, dispositionalism, dispositions, powers, categoricalism, powerful qualities view, fundamentality.

description: Metaphysical orthodoxy holds that a privileged minority of properties carve reality at its joints. These are the so-called fundamental properties. This thesis concerns the contemporary philosophical debate about the nature of fundamental properties. In particular, it aims to answer two questions: (1) What is the most adequate conception of fundamental properties? (2) What is the “big picture” world-view that emerges by adopting such a conception? I argue that a satisfactory answer to both questions requires us to embrace a novel conception of powerful qualities, according to which properties are at once dispositional and qualitative. By adopting the proposed conception of powerful qualities, an original theory of fundamental properties comes to light. I call it Dual-Aspect Account. In this thesis, I defend the Dual-Aspect Account and its superiority with respect to rival views of fundamental properties. I illustrate this claim by examining Dispositionalism, the view defended among others by Alexander Bird and Stephen Mumford, Categoricalism, which has been advocated notably by David Lewis and David Armstrong, and the Identity Theory of powerful qualities, primarily championed by C. B. Martin and John Heil. The latter is the standard conception of powerful qualities. However, in the literature, the Identity Theory faces the charge of contradiction. A preliminary task is therefore to show that a conception of powerful qualities is coherent. To accomplish this aim, I introduce the notion of an aspect of a property. On this interpretation, powerful qualities can be thought of as having dispositional and qualitative aspects. I show that such a conception allows us to disambiguate the claim that a property’s dispositionality is identical with its qualitativity, and evade the charge of contradiction. Aspects bring us other theoretical benefits. I illustrate this claim by showing how the Dual-Aspect Account offers us a promising theory of resemblance. I then compare its merits with David Armstrong’s theory of partial identity. The conclusion of this thesis is that the Dual-Aspect Account is better suited to capturing the world as we find it in everyday life and scientific investigation as compared to the theoretical positions examined.
Assessment OF, FOR and AS Learning: Students as Partners in Assessment
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: This Forum Insight aims to give both students and staff some initial thoughts on how they can facilitate students to become partners in the assessment process. It builds on the outputs of a workshop organised in partnership between the Union of Students in Ireland (USI) and the National Forum for the Enhancement of Teaching and Learning. It presents both ideas that students have some control over and ideas that staff could consider in their assessment designs.
An Introduction to the Learning Analytics and Educational Data Mining for Learning Impact Project
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: This Forum Insight introduces the key concepts of learning analytics and educational data mining and summarises the National Forum’s Learning Analytics and Educational Data Mining for Learning Impact Project, which runs from September 2016 to June 2017.
Additional file 1: of Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C
Creators: name: Lin, Zhaoyu
name: Liu, Fei
name: Shi, Peiliang
name: Song, Anying
name: Huang, Zan
name: Zou, Dayuan
name: Chen, Qin
name: Li, Jianxin
name: Gao, Xiang
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Table S1. Primer Sequences. (DOCX 17 kb)
title: 03_0307
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Exploring how respect is articulated in Irish education policy, curriculum, circulars and legislation
Creators: name: Mc Cormack, Orla
name: O'Flaherty, Joanne
name: O'Grady, Emmanuel
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 39
subject: Education

description: Respect as a term or value is often evoked to highlight a sense of esteem or right that an individual or group should require or be afforded. It is frequently viewed as relational, and central to the way people ought to relate to each other. However, the use of the term respect within classrooms, schools and policy can sometimes become so ubiquitous to the extent that it can become meaningless. Set against this context, this research analyses education documents relating to early childhood, primary and post-primary to consider the espoused positioning of respect within the Irish context. Sources were searched systematically using specific inclusion criteria, which resulted in 620 documents included in the sample, legislation (n = 40), policies (n = 50), active circulars (n = 179), archived circulars (n = 249) and curriculum specifications (n = 102). Following the application of thematic analysis, the authors suggest that ‘respect’ tends to be understood in six main ways: Respecting difference and diversity; mutual respect/ respect as relational; respecting the child; respecting the environment; respecting parents’ rights, views and values; and respecting the ‘ethos’ of the school. Some ways of understanding these conceptualisations and potential implications for schooling are discussed.
title: An investigation into the role of thiamine and magnesium in the pathophysiology and treatment of alcohol withdrawal syndrome
Creators: name: Maguire, Donogh
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Thiamine, magnesium, lactate, alcohol withdrawal syndrome, transketolase, pyruvate dehydrogenase, systemic inflammatory response, mortality.

description: Thiamine and magnesium are essential nutrients for healthy human metabolism. The current thesis examines the relationship between these essential nutrients and their relationship to chronic disease states in a population of patients presenting to the Emergency Department with alcohol withdrawal syndrome.
LT Telescope and IO:O Throughput
Creators: name: Smith, Robert
name: Steele, Iain
Publisher: name: figshare
Year: 2017
Subjects: subject: 20102 Astronomical and Space Instrumentation
subject: FOS: Physical sciences
subject: Instrumentation, Techniques, and Astronomical Observations

description: We measure the absolute photon efficiency of the Liverpool Telescope using observations of photometric standard stars and a throughput model of the IO:O instrument. Over a period of one year following mirror re-coating the telescope transmission is in the range 73-79% over 4000-10000 Angstroms. Transmission in the u'-band (~3500 Angstroms) is slightly lower at 65%. Immediately following mirror re-coating the throughput is shown to be consistent within 4% to predictions for two reflections from bare-aluminium-coated optics. The telescope throughput (two reflections) degrades at a rate ~0.0002 mag/day. Also presented are the effective wavelengths and widths for the u',g',r',i',z',B,V broad-band filters, taking into account all optical components of the system.
MOESM10 of Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease
Creators: name: Skinner, Michael
name: Ben Maamar, Millissia
name: Sadler-Riggleman, Ingrid
name: Beck, Daniel
name: Nilsson, Eric
name: McBirney, Margaux
name: Klukovich, Rachel
name: Xie, Yeming
name: Tang, Chong
name: Yan, Wei
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 10: Table S8. F3 H3K27me3 DHR pÂ <Â 1eâ 06.
Deep dive: training resources FAIRification, community and future opportunities
Creators: name: Braukmann, Ricarda
name: Newbold, Elizabeth
name: Leenarts, Ellen
name: Iulianna Van Der Lek
name: Shanmugasundaram Venkataraman
name: Brvar, Irena Vipavc
Publisher: name: Zenodo
Year: 2022
Subjects: SSHOC
Social Sciences and Humanities Open Cloud
European Open Science Cloud
EOSC
Interoperability
Training Community
Training Toolkit
Training

description: Moderator: Ricarda Braukmann (DANS, SSHOC) Elizabeth Newbold (STFC) Ellen Leenarts (SSHOC, DANS) Iulianna van der Lek (SSHOC, CLARIN) Shanmugasundaram Venkataraman (EOSC Future, OpenAIRE)  Irena Vipavc Brvar (Univerza v Ljubljani, CESSDA)