cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Spontaneous intra-abdominal hemorrhage: Looking for the cause.
Creators: name: Barba Arce, Ana Belén
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Emergency
subject: Abdomen
subject: CT-Angiography
subject: CT
subject: Surgery
subject: Embolisation
subject: Acute
subject: Haemorrhage
subject: Blood

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. To describe the clinic and to identify the most common causes of spontaneous intra-abdominal hemorrhage. 2. To explain the Computed Tomography (CT) study protocol in case of suspected acute bleeding. 3. To review the CT findings that are...
Additional file 1 of Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes
Creators: name: Ueno, Masanobu
name: Miyagawa, Ippei
name: Miyazaki, Yusuke
name: Hanami, Kentaro
name: Fukuyo, Shunsuke
name: Kubo, Satoshi
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Figure S1. Flow cytometry gating strategy. The proportion of A. CD4+ T cells subsets to CD3+ and CD4+ T cells (%), B. CD8+ T cells subsets to CD3+ and CD8+ T cells (%), C. a)-e) Activated CD4+ T cells to CD3+ and CD4+ T cells (%) f) Activated CD8+ T cells to CD3+ and CD8+ T cells (%), D. B cells subsets to CD3- and CD19+ B cells (%), E. Classical and non-classical monocytes to CD3-, CD19-, CD20- and CD14+ cells (%), F. Myeloid and Plasmacytoid DCs to CD3-, CD19-, CD20- CD14- and human leukocyte antigen-DR+ cells (%), G. CD16+ and CD16- NK cells to CD3-, CD19-, CD20- CD14- and CD56+ cells (%).
Strain driven sequential magnetic transitions in strained GdTiO3 on compressive substrates: a first-principles study
Creators: name: Yang, Li-Juan
name: Weng, Ya-Kui
name: Zhang, Hui-Min
name: Dong, Shuai
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The compressive strain effects on the magnetic ground state and electronic structure of strained GdTiO 3 have been studied by the first-principles method. Different from the congeneric YTiO3 and LaTiO3 cases both of which becomes the A-type antiferromagnetism on the (001) LaAlO3 substrate despite their contrastive magnetism, the ground state of strained GdTiO3 on the LaAlO3 substrate changes from the original ferromagnetism to G-type antiferromagnetim, instead of the A-type one although Gd 3+ is between Y3+ and La3+. Only when the in-plane compressive strain is large enough, e.g. on the (001) YAlO3 substrate, the ground state finally becomes the A-type one. The band structure calculation shows that these compressive strained GdTiO3 remain insulating, although the band gap changes a little in these strained GdTiO3.
description: 18 pages, 5 figures, 3 tables
Localizing gravitational wave sources with optical telescopes and combining electromagnetic and gravitational wave data
Creators: name: Ghosh, Shaon
name: Nelemans, Gijs
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Neutron star binaries, which are among the most promising sources for the direct detection of gravitational waves (GW) by ground based detectors, are also potential electromagnetic (EM) emitters. Gravitational waves will provide a new window to observe these events and hopefully give us glimpses of new astrophysics. In this paper, we discuss how EM information of these events can considerably improve GW parameter estimation both in terms of accuracy and computational power requirement. And then in return how GW sky localization can help EM astronomers in follow-up studies of sources which did not yield any prompt emission. We discuss how both EM source information and GW source localization can be used in a framework of multi-messenger astronomy. We illustrate how the large error regions in GW sky localizations can be handled in conducting optical astronomy in the advance detector era. We show some preliminary results in the context of an array of optical telescopes called BlackGEM, dedicated for optical follow-up of GW triggers, that is being constructed in La Silla, Chile and is expected to operate concurrent to the advanced GW detectors.
description: 8 pages, 8 figures, Proceeding for Sant Cugat Forum for Astrophysics
title: Electrochemically switchable calixarene ionophores.
Creators: name: Dougherty, Gary.
Publisher: name: University of Liverpool Repository
Year: 2023

description: The synthesis of a series of p-tert-butylcalixI4Iarcne based, electrochemically switchable, ionophores (1), (2), (3), (4) and (5) is described. Their electrochemical properties were investigated in the presence of added Croup I metal perchloratcs. Both compounds (1) and (2) displayed no enhancement of binding for metal ions, due to electrostatic interactions, upon electrochemical reduction. This behaviour is explained on steric grounds, as deduced by molecular modelling. Compounds (3), (4) and (5) all display significant enhancements of metal ion binding upon electrochemical reduction. Compounds (4) and (5) appear to display a high selectivity for sodium ions over other Croup I metal ions. Compound (3) displayed the highest binding enhancements yet recorded for both sodium (3.138 x loS) and potassium (1.398 x 103) ions. Compound (6) (from which (3), (4) and (5) were malic) could be converted to m,my other compounds in which the side arms bear difierent functional groups in an eiiort to control selectivity. For example thio esters or thin arnides for silver, ethyl groups tor potassium.
Signatures of Secondary Collisionless Magnetic Reconnection Driven by Kink Instability of a Flux Rope
Creators: name: Markidis, S.
name: Lapenta, G.
name: Delzanno, G. L.
name: Henri, P.
name: Goldman, M. V.
name: Newman, D. L.
name: Intrator, T.
name: Laure, E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: The kinetic features of secondary magnetic reconnection in a single flux rope undergoing internal kink instability are studied by means of three-dimensional Particle-in-Cell simulations. Several signatures of secondary magnetic reconnection are identified in the plane perpendicular to the flux rope: a quadrupolar electron and ion density structure and a bipolar Hall magnetic field develop in proximity of the reconnection region. The most intense electric fields form perpendicularly to the local magnetic field, and a reconnection electric field is identified in the plane perpendicular to the flux rope. An electron current develops along the reconnection line in the opposite direction of the electron current supporting the flux rope magnetic field structure. Along the reconnection line, several bipolar structures of the electric field parallel to the magnetic field occur making the magnetic reconnection region turbulent. The reported signatures of secondary magnetic reconnection can help to localize magnetic reconnection events in space, astrophysical and fusion plasmas.
Small-Molecule Ligands of Methyl-Lysine Binding Proteins: Optimization of Selectivity for L3MBTL3
Creators: name: Arrowsmith, Cheryl H.
name: Janzen, William P.
name: Krichevsky, Liubov
name: Norris, Jacqueline L.
name: Korboukh, Victoria K.
name: Kireev, Dmitri B.
name: James, Lindsey I.
name: Jin, Jian
name: Herold, J. Martin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Lysine methylation is a key epigenetic mark, the dysregulation of which is linked to many diseases. Small molecule antagonism of methyl-lysine (Kme) binding proteins that recognize such epigenetic marks can improve our understanding of these regulatory mechanisms and potentially validate Kme binding proteins as drug discovery targets. We previously reported the discovery of 1 (UNC1215), the first potent and selective small molecule chemical probe of a methyl-lysine reader protein, L3MBTL3, which antagonizes the mono- and dimethyl-lysine reading function of L3MBTL3. The design, synthesis, and structure activity relationship studies that led to the discovery of 1 are described herein. These efforts established the requirements for potent L3MBTL3 binding and enabled the design of novel antagonists, such as compound 2 (UNC1679), that maintain in vitro and cellular potency with improved selectivity against other MBT-containing proteins. The antagonists described were also found to effectively interact with unlabeled endogenous L3MBTL3 in cells.
Additional file 2 of Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes
Creators: name: Ueno, Masanobu
name: Miyagawa, Ippei
name: Miyazaki, Yusuke
name: Hanami, Kentaro
name: Fukuyo, Shunsuke
name: Kubo, Satoshi
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 2: Figure S2. Comparison of treatment response at month 1 and 3. A. Rate of DAPSA-LDA Responders (%) B. Rate of DAPSA-REM Responders C. Rate of PPPASI-50 Responders (%) D. Rate of PPPASI-75 Responders E. Rate of PPPASI-90 Responders (%) at month q1 and 3. *p<0.05, by Fisher’s exact test. Abbreviation: PPPASI; Palmoplantar Pustulosis Area. Severity index, DAPSA; disease activity in psoriatic arthritis, LDA; low disease activity, REM; remission.
De soevereinen in België en elders: Vraagtekens bij staat, burgerschap en sociaal contract anno 2024
Creators: name: de Boer, Luuk
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 480302
subject: Comparative law
classificationCode: 480410
subject: Legal theory, jurisprudence and legal interpretation
classificationCode: 480405
subject: Law and society and socio-legal research

description: This extensive article is the product of my contribution to a KU Leuven-conference on contemporary citizenship. It offers the first cross-national explanation of the international sovereign citizen movement. Its roots I trace to libertarian criticism of social contract theory; its popularity I explain sociologically, stressing the pandemic-engendered clash between the promise of individual autonomy and the reality of minimal control.
title: Rectus abdominis and lumbar multifidus muscles evaluation by Ultrasound
Creators: name: Santos, Rute
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Radiographers
subject: Musculoskeletal soft tissue
subject: Musculoskeletal system
subject: Ultrasound
subject: Experimental investigations
subject: Tissue characterisation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Nowadays, postural changes affect all different age groups by the use of computers, cell phones or sedentary routines (1). A healthy spine needs a good posture, exercise and stretching (2). The promotion of a healthy spine and the prevention of...
A New Sample of Cool Subdwarfs from SDSS: Properties and Kinematics
Creators: name: Savcheva, Antonia
name: West, Andrew A.
name: Bochanski, John J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a new sample of M subdwarfs compiled from the 7th data release of the Sloan Digital Sky Survey. With 3517 new subdwarfs, this new sample significantly increases the number of spectroscopically confirmed low-mass subdwarfs. This catalog also includes 905 extreme and 534 ultra sudwarfs. We present the entire catalog including observed and derived quantities, and template spectra created from co-added subdwarf spectra. We show color-color and reduced proper motion diagrams of the three metallicity classes, which are shown to separate from the disk dwarf population. The extreme and ultra subdwarfs are seen at larger values of reduced proper motion as expected for more dynamically heated populations. We determine 3D kinematics for all of the stars with proper motions. The color-magnitude diagrams show a clear separation of the three metallicity classes with the ultra and extreme subdwarfs being significantly closer to the main sequence than the ordinary subdwarfs. All subdwarfs lie below (fainter) and to the left (bluer) of the main sequence. Based on the average $(U,V,W)$ velocities and their dispersions, the extreme and ultra subdwarfs likely belong to the Galactic halo, while the ordinary subdwarfs are likely part of the old Galactic (or thick) disk. An extensive activity analysis of subdwarfs is performed using H$α$ emission and 208 active subdwarfs are found. We show that while the activity fraction of subdwarfs rises with spectral class and levels off at the latest spectral classes, consistent with the behavior of M dwarfs, the extreme and ultra subdwarfs are basically flat.
description: 66 pages, 23 figures, accepted in ApJ
Additional file 3 of Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes
Creators: name: Ueno, Masanobu
name: Miyagawa, Ippei
name: Miyazaki, Yusuke
name: Hanami, Kentaro
name: Fukuyo, Shunsuke
name: Kubo, Satoshi
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 3: Figure S3. Impact of guselkumab treatment on peripheral blood immune phenotypes. Changes in the proportion of A. CD4+ T cells subsets to CD3+ and CD4+ T cells (%), B. CD8+ T cells subsets to CD3+ and CD8+ T cells (%), C. a)-e) Activated CD4+ T cells to CD3+ and CD4+ T cells (%) f) Activated CD8+ T cells to CD3+ and CD8+ T cells (%), D. B cells subsets to CD3- and CD19+ B cells (%), E. Classical and non-classical monocytes to CD3-, CD19-, CD20- and CD14+ cells (%), F. Myeloid and Plasmacytoid DCs to CD3-, CD19-, CD20- CD14- and human leukocyte antigen-DR+ cells (%), G. CD16+ and CD16- NK cells to CD3-, CD19-, CD20- CD14- and CD56+ cells(%). *p<0.05, by Wilcoxon signed rank test.
Additional file 4 of Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes
Creators: name: Ueno, Masanobu
name: Miyagawa, Ippei
name: Miyazaki, Yusuke
name: Hanami, Kentaro
name: Fukuyo, Shunsuke
name: Kubo, Satoshi
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 4: Figure S4. Impact of adalimumab treatment on peripheral blood immune phenotypes. Changes in the proportion of A. CD4+ T cells subsets to CD3+ and CD4+ T cells (%), B. CD8+ T cells subsets to CD3+ and CD8+ T cells (%), C. a)-c) Activated CD4+ T cells to CD3+ and CD4+ T cells (%) d) Activated CD8+ T cells to CD3+ and CD8+ T cells (%), D. B cells subsets to CD3- and CD19+ B cells (%), E. Classical and non-classical monocytes to CD3-, CD19-, CD20- and CD14+ cells (%), F. Myeloid and Plasmacytoid DCs to CD3-, CD19-, CD20- CD14- and human leukocyte antigen-DR+ cells (%), G. CD16+ and CD16- NK cells to CD3-, CD19-, CD20- CD14- and CD56+ cells(%). *p<0.05, by Wilcoxon signed rank test.
title: Usefulness of right ventricular function with time intensity curve of rest perfusion cardiac MRI
Creators: name: Tachibana, Kenta
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Cardiac
subject: MR-Functional imaging
subject: Technical aspects
subject: Haemodynamics / Flow dynamics

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Background Recently, right ventricular ejection fraction (RV-EF) has been shown to be an important prognostic factor of left heart failure, in addition to left ventricle ejection fraction (LV-EF), and is used to conventionally measure cardiac...
title: Development of an abdominal phantom simulating the fibrotic lesions for diffusion-weighted imaging
Creators: name: Harada, Nobuaki
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Tissue characterisation
subject: Pathology
subject: Technology assessment
subject: Molecular imaging
subject: MR-Diffusion/Perfusion
subject: Abdomen

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Diffusion-Weighted Imaging (DWI) is a magnetic resonance imaging (MRI) technique which has important roles for detection of acute cerebral infarction, characterization of tumorous lesions, and assessment of therapeutic response (1-3). The...
Hybrid optomechanical cooling by atomic $Λ$ systems
Creators: name: Bariani, F.
name: Singh, S.
name: Buchmann, L. F.
name: Vengalattore, M.
name: Meystre, P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We investigate a hybrid quantum system consisting of a cavity optomechanical device optically coupled to an ultracold quantum gas. We show that the dispersive properties of the ultracold gas can be used to dramatically modify the optomechanical response of the mechanical resonator. We examine hybrid schemes wherein the mechanical resonator is coupled either to the motional or the spin degrees of freedom of the ultracold gas. In either case, we find an enhancement of more than two orders of magnitude in optomechanical cooling due to this hybrid interaction. Significantly, based on demonstrated parameters for the cavity optomechanical device, we identify regimes that enable the ground state cooling of the resonator from room temperature. In addition, the hybrid system considered here represents a powerful interface for the use of an ultracold quantum gas for state preparation, sensing and quantum manipulation of a mesoscopic mechanical resonator.
description: 14 pages, 12 figures
title: Preliminary experiences of DBT (Digital Breast Tomosynthesis) and hybrid 18F–FDG-PETMR for neoadjuvant chemotherapy (NAC) cases in breast cancer
Creators: name: Uchiyama, Nachiko
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Pathology
subject: Image verification
subject: Image registration
subject: Diagnostic procedure
subject: Computer Applications-General
subject: Chemotherapy
subject: PET-MR
subject: Image manipulation / Reconstruction
subject: Digital radiography
subject: Oncology
subject: Management
subject: Breast

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To verify clinical findings of new diagnostic modalities of DBT and 18F–FDG-PETMR for evaluations of loco-regional staging and treatment response of NAC in comparison with pathological...
Integrable Systems with Unitary Invariance from Non-stretching Geometric Curve Flows in the Hermitian Symmetric Space Sp(n)/U(n)
Creators: name: Anco, Stephen C.
name: Asadi, Esmaeel
name: Dogonchi, Asieh
Publisher: name: arXiv
Year: 2014
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: A moving parallel frame method is applied to geometric non-stretching curve flows in the Hermitian symmetric space Sp(n)/U(n) to derive new integrable systems with unitary invariance. These systems consist of a bi-Hamiltonian modified Korteweg-de Vries equation and a Hamiltonian sine-Gordon (SG) equation, involving a scalar variable coupled to a complex vector variable. The Hermitian structure of the symmetric space Sp(n)/U(n) is used in a natural way from the beginning in formulating a complex matrix representation of the tangent space sp(n)/u(n) and its bracket relations within the symmetric Lie algebra (u(n),sp(n)).
description: 14 pages
Additional file 5 of Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes
Creators: name: Ueno, Masanobu
name: Miyagawa, Ippei
name: Miyazaki, Yusuke
name: Hanami, Kentaro
name: Fukuyo, Shunsuke
name: Kubo, Satoshi
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 5: Figure S5. Changes in serum TNF-α and IL-17 concentration during 6 months of treatment. TNF-α (pg/ml), B. IL-17A (fg/ml). *p<0.05, by Wilcoxon signed rank test. TNF; tumor necrosis factor.
فضاء النص السردي عند الكاتبة الأستاذة ريم أبوعيد
Creators: name: Mounir, Ayman
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 470530
subject: Stylistics and textual analysis

description: ان فضاء النص السردي في رواية "ليل وناي وقمر" يؤكد على نجاح الكاتبة في اختيار معجم متميز أتاح للقارئ إمكانية الوصول الى مضمون العمل. من هنا نستطيع التأكيد على أن التوظيف الجمالي لهذا العُنوان بهذا الشكل المعجمي رجع الى رغبة الكاتبة في استيفاء المعنى وتعميق جمالية لغة الكلام وتقريب وظيفة العنوان التأثيرية الى ذهن القارئ.
Smart electronic device for air quality and exposure risk assessment
Creators: name: Taamte, Jacob Mbarndouka
name: Siaka, Yvette Flore Tchuente
name: Nducol, Nasser
name: Younui, Susan Yakum-Ntaw
name: Ahmadou, Gouroudja
name: Essama, René Claude Etende
name: Noubé, Michaux Kountchou
name: Saïdou
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: This article reports on the measurement of air pollutants and assessment of health exposure risks in two reference hospitals in the city of Yaoundé, using a locally manufactured smart electronic device for the measurement of highly toxic air pollutants. This low-cost device is based on an Atmega328 microcontroller, toxic gas sensors (O3, PM2.5, CO, CO2 and NO2), temperature (T), relative humidity (RH) sensors, and XBee modules to establish the Internet of Things (IoT). In each of the two hospitals, 2 weeks of measurements conducted from October 15 to 30, 2023 at Biyem-assi Hospital and from September 1 to 15, 2023 at Central Hospital. The average values obtained were 0.96 ± 0.06 ppm and 0.37 ± 0.09 ppm for O3, 39.66 ± 10 µg/m3 and 39.72 ± 10 µg/m3 for PM2.5, 0.41 ± 0.01 ppm and 0.42 ± 0.02 ppm for CO, 316.55 ± 63 ppm and 305.84 ± 89 ppm for CO2, and 0.43 ± 0.01 ppm and 0.45 ± 0,02 ppm for NO2 in Biyem-assi and Central Hospitals, respectively. These values were used to assess the risk of exposure through the Air Quality Index (AQI) and the Air Quality Health Index (AQHI2.5).
title: Incidence of normal variants of Circle of Willis in Nepalese population: a CT angiographic study
Creators: name: Poudel, Arun
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Arteriovenous malformations
subject: Arteriosclerosis
subject: Aneurysms
subject: Angioplasty
subject: CT-Angiography
subject: Neuroradiology brain
subject: Arteries / Aorta
subject: Anatomy

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The Circle of Willis represents the important anastomotic cerebral vessels at the base of the brain.The blood supply to the brain consists of two vertebral arteries and two internal carotid arteries which distributes oxygen rich arterial blood to...
title: Preoperative Localization of Parathyroid Adenomas using Four-dimensional Computed Tomography (4DCT)
Creators: name: Zeina, Abdel-Rauf
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Head and neck
subject: CT
subject: Diagnostic procedure
subject: Metabolic disorders

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Four-dimensional parathyroid computed tomography (4D-CT) is a relatively new parathyroid imaging technique that provides functional and highly detailed anatomic information about parathyroid tumors. The aim of this retrospective study was to assess...
Low-metallicity star formation: Relative impact of metals and magnetic fields
Creators: name: Peters, Thomas
name: Schleicher, Dominik R. G.
name: Smith, Rowan J.
name: Schmidt, Wolfram
name: Klessen, Ralf S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Low-metallicity star formation poses a central problem of cosmology, as it determines the characteristic mass scale and distribution for the first and second generations of stars forming in our Universe. Here, we present a comprehensive investigation assessing the relative impact of metals and magnetic fields, which may both be present during low-metallicity star formation. We show that the presence of magnetic fields generated via the small-scale dynamo stabilises the protostellar disc and provides some degree of support against fragmentation. In the absence of magnetic fields, the fragmentation timescale in our model decreases by a factor of ~10 at the transition from Z=0 to Z>0, with subsequently only a weak dependence on metallicity. Similarly, the accretion timescale of the cluster is set by the large-scale dynamics rather than the local thermodynamics. In the presence of magnetic fields, the primordial disc can become completely stable, therefore forming only one central fragment. At Z>0, the number of fragments is somewhat reduced in the presence of magnetic fields, though the shape of the mass spectrum is not strongly affected in the limits of the statistical uncertainties. The fragmentation timescale, however, increases by roughly a factor of 3 in the presence of magnetic fields. Indeed, our results indicate comparable fragmentation timescales in primordial runs without magnetic fields and Z>0 runs with magnetic fields.
description: MNRAS in press
title: Local Staging of Colorectal Cancer Using Multidetector Computed Tomography (MDCT)
Creators: name: Zeina, Abdel-Rauf
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Colon
subject: CT
subject: Staging
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Imaging plays an important role in diagnosis, staging, treatment planning, and follow-up of patients with colorectal cancer (CRC). The main objective of this study was to evaluate the capability of quantitative assessment of the pericolonic...
Additional file 6 of Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes
Creators: name: Ueno, Masanobu
name: Miyagawa, Ippei
name: Miyazaki, Yusuke
name: Hanami, Kentaro
name: Fukuyo, Shunsuke
name: Kubo, Satoshi
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 6: Supplementary Table S1. Flow cytometry antibody panels used in this study.
Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8
Creators: name: Brown, Peter J.
name: Jin, Jian
name: Bleich, Rachel M.
name: Ma, Anqi
name: Li, Fengling
name: Frye, Stephen V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The lysine methyltransferase SETD8 is the only known methyltransferase that catalyzes monomethylation of histone H4 lysine 20 (H4K20). Monomethylation of H4K20 has been implicated in regulating diverse biological processes including the DNA damage response. In addition to H4K20, SETD8 monomethylates non-histone substrates including proliferating cell nuclear antigen (PCNA) and promotes carcinogenesis by deregulating PCNA expression. However, selective inhibitors of SETD8 are scarce. The only known selective inhibitor of SETD8 to date is nahuoic acid A, a marine natural product, which is competitive with the cofactor. Here, we report the discovery of the first substrate-competitive inhibitor of SETD8, UNC0379 (1). This small-molecule inhibitor is active in multiple biochemical assays. Its affinity to SETD8 was confirmed by ITC (isothermal titration calorimetry) and SPR (surface plasmon resonance) studies. Importantly, compound 1 is selective for SETD8 over 15 other methyltransferases. We also describe structure–activity relationships (SAR) of this series.
title: Impingement of offset jets on rigid and movable beds.
Creators: name: Ali Akbar Salehi Neyshabouri, Seyed
Publisher: name: University of Liverpool Repository
Year: 2023

description: The present thesis describes an experimental and theoretical investigation of the flow field and scour action of an offset jet. The hydraulic characteristics of the offset jet and the resulting scour developed in the bed were investigated in the laboratory. Tests were carried out using a fixed bed and a single offset ratio (height of jet above bed / jet thickness). Three flow rates were used. Velocity measurements in two directions, especially in the recirculating zone, were of help in understanding the flow field and in providing the necessary data for comparison with the theoretical results. The development of scour, on a uniform sand, was monitored at set time intervals, in most cases until the asymptotic state was reached. A new effective and simple method for measuring the scour profile, while the experiment was running, was devised. The experiments were conducted using four different offset ratios and several flow-rates. Results showed dependency of the scour characteristics on Froude number, time and especially the offset ratio. The findings of each experiment were combined dimensionlessly to produce relationships which describe the development of scour characteristics for the tested range of parameters. Scour profiles were found to be similar for a given offset ratio, but differed from one offset ratio to another. The second part of the work was concerned with developing a general integral method capable of the prediction of velocity fields of different flow situations, including those of offset jet impinging on rigidand eroded beds. The combination of strip integral method in a curvilinear system with the k-E and algebraic stress turbulence models provided such a method. Application of this method to a variety of selected test cases revealed the ability of the model to capture the main features of the flow within the considered range of interest. The algebraic stress model was found to give better results in curved and wall effected flows.
One-year incidence of chemotherapy-induced peripheral neuropathy in oxaliplatin- or taxane-based chemotherapy: a multicenter, prospective registry study (MiroCIP study)
Creators: name: Misawa, Sonoko
name: Denda, Tadamichi
name: Kodama, Sho
name: Suzuki, Takuji
name: Naito, Yoichi
name: Kogawa, Takahiro
name: Takada, Mamoru
name: Hino, Aoi
name: Shiosakai, Kazuhito
name: Kuwabara, Satoshi
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Chemotherapy-induced peripheral neuropathy (CIPN) and its associated pain negatively affect patient outcomes and quality of life (QoL). The two-part MiroCIP study included interventional and prospective observational studies. Here, we report the latter, describing CIPN incidence, risk factors, and outcomes. This 1-year, multicenter, prospective registry study (May 2021–April 2023) included patients aged ≥ 20 years with colorectal, gastric, non-small cell lung, or breast cancer who were scheduled to undergo chemotherapy with oxaliplatin or taxane. The primary endpoint was Grade ≥ 2 sensory CIPN incidence within 12 months after chemotherapy initiation. Subjective and objective symptoms, QoL, and pain were evaluated. Overall, 216 patients (female, 64.4%; mean age, 60.3 years) were included. Ninety-one (42.1%) and 131 (60.6%) patients received oxaliplatin- and taxane-based chemotherapy, respectively (six received both and were included in both groups). Grade ≥ 2 CIPN occurred in 96 patients (44.4%; 72.8/100 person-years), with 70.8% (68/96 patients) developing symptoms within 90 days. The most prominent CIPN symptoms were limb numbness/tingling and decreased vibration sensibility. No clinically meaningful risk factors were identified. We clarified CIPN incidence in cancer patients. Subjective symptoms (limb numbness/tingling, decreased vibration sensibility) and pain are important CIPN symptoms requiring careful monitoring. jRCTs031210101.
title: Acute spinal cord infarction in children – the diagnostic role of MRI
Creators: name: Zabret, Urška
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Trauma
subject: Acute
subject: Imaging sequences
subject: Diagnostic procedure
subject: MR
subject: Paediatric
subject: Neuroradiology spine
subject: CNS
subject: Ischaemia / Infarction

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To highlight magnetic resonance imaging (MRI) findings in spinal cord ischemia, to overview pathology, clinical characteristics and main differential diagnosis, to present features of fibrocartilaginous embolism, a possible cause of acute spinal...
Skin spots on ‘Cripps Pink’ and ‘Elstar’ apples are identical
Creators: name: Khanal, Bishnu P.
name: Knoche, Moritz
Publisher: name: Journal of Applied Botany and Food Quality
Year: 2024

description: Brown spots have recently been reported on the surfaces of ‘Cripps Pink’ apples, grown in Marsillargues, France. Preliminary observations suggest the symptoms on ‘Cripps Pink’ apples resemble those reported earlier on ‘Elstar’ apples and then referred to as ‘Elstar skin spots’. Elstar skin spots occur particularly in coastal production areas of northern Europe, and in rainy seasons. The objective of this study was to establish more definitively whether the skin spots observed on ‘Cripps Pink’ are identical to those reported on ‘Elstar’. Hence, the morphological and anatomical characteristics of ‘Cripps Pink’ skin spots were assessed in more detail. The skin spots on ‘Cripps Pink’ develop on the non-blush side of the fruit. High resolution scanning light microscopy revealed a network of cuticular microcracks in both symptomatic and non-symptomatic regions of an affected fruit. When fruits with microcracks were dipped in a 1:1 chloroform:methanol mixture, the width and depth of the microcracks increased, indicating that the microcracks had previously been partially filled with wax. The microcracks on a symptomatic surface were wider and deeper than those on a non-symptomatic surface. After the cuticular wax had been extracted (as above), the microcracks on the symptomatic surface were found to be partially infiltrated with the fluorescent dye acridine orange; but not so the microcracks on a non-symptomatic surface. The fruit skin of symptomatic apples had a higher rate of water loss than that of non-symptomatic apples. Microscopy revealed that the epidermal and some of the hypodermal cells beneath the microcracks within a symptomatic area were brown and their cell walls lignified. We infer from these observations that the skin spots on ‘Cripps Pink’ are identical to the well-known skin spots on ‘Elstar’ apples.
description: Journal of Applied Botany and Food Quality, Vol. 97 (2024): Journal of Applied Botany and Food Quality
Substituted N -(Biphenyl-4′-yl)methyl ( R )-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium Channels
Creators: name: Dustrude, Erik T.
name: Kohn, Harold
name: Wilson, Sarah M.
name: Yang, Xiao-Fang
name: Lee, Hyosung
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: We prepared 13 derivatives of N-(biphenyl-4′-yl)methyl (R)-2-acetamido-3-methoxypropionamide that differed in type and placement of a R-substituent in the terminal aryl unit. We demonstrated that the R-substituent impacted the compound’s whole animal and cellular pharmacological activities. In rodents, select compounds exhibited excellent anticonvulsant activities and protective indices (PI = TD50/ED50) that compared favorably with clinical antiseizure drugs. Compounds with a polar, aprotic R-substituent potently promoted Na+ channel slow inactivation and displayed frequency (use) inhibition of Na+ currents at low micromolar concentrations. The possible advantage of affecting these two pathways to decrease neurological hyperexcitability is discussed.
title: Fatigue levels in female Maltese patients undergoing radiotherapy for early stage breast cancer
Creators: name: Farrugia, Maria
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Radiation therapy / Oncology
subject: Digital radiography
subject: Breast
subject: Cancer
subject: Radiation effects

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Breast cancer is the malignancy with the highest incidence (Figure1) [1] amongst Maltese females (n=300) and also in other European countries [2] With the number of cases of breast cancer being diagnosed, it is of relevance to understand the side...
Stellar Chemical Abundances: In Pursuit of the Highest Achievable Precision
Creators: name: Bedell, M.
name: Melendez, J.
name: Bean, J.
name: Ramirez, I.
name: Leite, P.
name: Asplund, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The achievable level of precision on photospheric abundances of stars is a major limiting factor on investigations of exoplanet host star characteristics, the chemical histories of star clusters, and the evolution of the Milky Way and other galaxies. While model-induced errors can be minimized through the differential analysis of spectrally similar stars, the maximum achievable precision of this technique has been debated. As a test, we derive differential abundances of 19 elements from high-quality asteroid-reflected solar spectra taken using a variety of instruments and conditions. We treat the solar spectra as being from unknown stars and use the resulting differential abundances, which are expected to be zero, as a diagnostic of the error in our measurements. Our results indicate that the relative resolution of the target and reference spectra is a major consideration, with use of different instruments to obtain the two spectra leading to errors up to 0.04 dex. Use of the same instrument at different epochs for the two spectra has a much smaller effect (~0.007 dex). The asteroid used to obtain the solar standard also has a negligible effect (~0.006 dex). Assuming that systematic errors from the stellar model atmospheres have been minimized, as in the case of solar twins, we confirm that differential chemical abundances can be obtained at sub-0.01 dex precision with due care in the observations, data reduction and abundance analysis.
description: Accepted for publication in ApJ; 13 pages, 6 figures, 7 tables
Highly frustrated spin-lattice models of magnetism and their quantum phase transitions: A microscopic treatment via the coupled cluster method
Creators: name: Bishop, R. F.
name: Li, P. H. Y.
name: Campbell, C. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We outline how the coupled cluster method of microscopic quantum many-body theory can be utilized in practice to give highly accurate results for the ground-state properties of a wide variety of highly frustrated and strongly correlated spin-lattice models of interest in quantum magnetism, including their quantum phase transitions. The method itself is described, and it is shown how it may be implemented in practice to high orders in a systematically improvable hierarchy of (so-called LSUB$m$) approximations, by the use of computer-algebraic techniques. The method works from the outset in the thermodynamic limit of an infinite lattice at all levels of approximation, and it is shown both how the "raw" LSUB$m$ results are themselves generally excellent in the sense that they converge rapidly, and how they may accurately be extrapolated to the exact limit, $m \rightarrow \infty$, of the truncation index $m$, which denotes the {\it only} approximation made. All of this is illustrated via a specific application to a two-dimensional, frustrated, spin-half $J^{XXZ}_{1}$--$J^{XXZ}_{2}$ model on a honeycomb lattice with nearest-neighbor and next-nearest-neighbor interactions with exchange couplings $J_{1}>0$ and $J_{2} \equiv κJ_{1} > 0$, respectively, where both interactions are of the same anisotropic $XXZ$ type. We show how the method can be used to determine the entire zero-temperature ground-state phase diagram of the model in the range $0 \leq κ\leq 1$ of the frustration parameter and $0 \leq Δ\leq 1$ of the spin-space anisotropy parameter. In particular, we identify a candidate quantum spin-liquid region in the phase space.
Additional file 7 of Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes
Creators: name: Ueno, Masanobu
name: Miyagawa, Ippei
name: Miyazaki, Yusuke
name: Hanami, Kentaro
name: Fukuyo, Shunsuke
name: Kubo, Satoshi
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 7: Supplementary Table S2. Comparison of activated Th1 and Th17 at baseline between with DMARDs group (N = 16) and without DMARDs group (N = 6). Data are shown by median(quartile) or n (%). P values were determined by the Wilcoxon rank sum test. p*<0.05: with DMARDs (N = 16) vs without DMARDs (N = 6).
UNC2025 , a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor
Creators: name: Lee, Minjung
name: Glaros, Trevor G.
name: Zhang, Weihe
name: Zhang, Dehui
name: Cummings, Christopher T.
name: Frye, Stephen V.
name: Hunter, Debra
name: Sather, Susan
name: Wang, Xiaodong
name: Newton, Dianne L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: We previously reported a potent small molecule Mer tyrosine kinase inhibitor UNC1062. However, its poor PK properties prevented further assessment in vivo. We report here the sequential modification of UNC1062 to address DMPK properties and yield a new potent and highly orally bioavailable Mer inhibitor, 11, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow. Kinome profiling versus more than 300 kinases in vitro and cellular selectivity assessments demonstrate that 11 has similar subnanomolar activity against Flt3, an additional important target in acute myelogenous leukemia (AML), with pharmacologically useful selectivity versus other kinases examined.
title: Reliability of the apparent diffusion coefficient assessment of cervical lymph nodes in phantoms and healthy volunteers
Creators: name: Beaumont, Hubert
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Oncology
subject: Molecular imaging
subject: Lymph nodes
subject: MR-Diffusion/Perfusion
subject: Experimental investigations
subject: Instrumentation
subject: Normal variants

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Apparent Diffusion Coefficient (ADC) can quantify the level of free water diffusion restricted by an increase in tissue cellularity. Applications of ADC in cancer imaging has motivated intensive research: ADC is now one of the main QIBs derived from...
Frequency comb vernier spectroscopy in the near infrared
Creators: name: Zhu, F.
name: Bounds, J.
name: Bicer, A.
name: Strohaber, J.
name: Kolomenskii, A. A.
name: Gohle, C.
name: Amani, M.
name: Schuessler, H. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We perform femtosecond frequency comb vernier spectroscopy in the near infrared with a femtosecond Er doped fiber laser, a scanning high-finesse cavity and an InGaAs camera. By utilizing the properties of a frequency comb and a scanning high-finesse cavity such spectroscopy provides broad spectral bandwidth, high spectral resolution, and high detection sensitivity on a short time scale. We achieved an absorption sensitivity of ~8E-8 cm-1Hz-1/2 corresponding to a detection limit of ~70 ppbv for acetylene, with a resolution of ~1.1 GHz in single images taken in 0.5 seconds and covering a frequency range of ~5 THz. These measurements have broad applications for sensing other greenhouse gases in this fingerprint near IR region with a simple apparatus.
description: 14 pages, 5 figures