cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Network analysis of maternal parenting practices and adolescent mental health problems: a longitudinal study
Creators: name: Sun, Xinlu
name: Yuan, Ting
name: Chen, Feifei
name: Li, Yan
name: Jiang, Nengzhi
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Science Policy
Mental Health

description: Supplementary Material 1. Additional file 1: Table S1. Values of EI centrality indices. Figure S1. Confidence intervals around edge weights for T1-network (a) and T2-network (b). Figure S2. Edge weight difference tests for T1-network (a) and T2-network (b). Figure S3. Centrality difference tests for EI for T1-network (a) and T2-network (b). Figure S4. Temporal network containing autoregressive paths. Figure S5. Confidence intervals around edge weights for temporal network. Figure S6. Edge weight difference tests for temporal network. Figure S7. Centrality difference tests for in-prediction (a for cross-lagged, c for cross-construct) and out-prediction (b for cross-lagged, d for cross-construct)
Two-Stage Risk Analysis Application in Maritime Tanker Transportation
Creators: name: DEMIRCİ, Mücahit
name: ARICAN, Ozan Hikmet
Publisher: name: Zenodo
Year: 2025

description: In maritime transport, tanker ships have a strategic advantage in company fleets. It is necessary to evaluate the risks that may occur in this area. The aim of this study is to determine the risks that may occur in maritime tanker transport and to propose preventive measures in this direction. In addition, determining the importance levels of risk phenomena is another issue aimed within the scope of the study. In this context, a two-stage evaluation process was applied in the study. In the first phase of the study, Failure Mode Effects Analysis (FMEA) was applied. Risk factors determined in line with the views of experts in the field were put forward and their risk priority number was determined. Afterwards, preventive actions were identified in the study. In the second phase of the study, Fuzzy AHP method was applied. In this direction, risk factors were categorised and made comparable among themselves. Importance levels were determined within the scope of the opinions of sector representatives who are experts in their field. Thus, the objectivity level of the study was improved. According to the results of the study, the importance level of the administration and maintenance risk group was found to be the highest. Under this heading, maintenance deficiencies on board, transport of chemical hazardous materials and failure to manage them properly, failure to supply spare parts and critical equipment are listed. The technical failures group was evaluated as the other most important risk group. Under this heading, there are rudder equipment failure, machinery failure and generator failure risk situations.
Αναγνώριση και Ταυτοποίηση Προσώπων για Σκοπούς Δίωξης Εγκλήματος Σύμφωνα με το Σχέδιο Κανονισμού της ΕΕ για την Τεχνητή Νοημοσύνη
Creators: name: Παντιέρα, Χρυσούλα
Publisher: name: Επιθεώρηση Δικαίου Πληροφορικής
Year: 2024

description: Ο τομέας των τεχνολογιών αναγνώρισης προσώπων αναπτύσσεται γρήγορα, εγείροντας ερωτήματα για την ισορροπία μεταξύ ατομικού απορρήτου και κοινωνικής ασφάλειας. Η χρήση τέτοιων τεχνολογιών από τις υπηρεσίες επιβολής του νόμου αυξάνεται, προκαλώντας ανησυχίες σχετικά με την επιβολή και την επιτρεπτή έκταση της παρακολούθησης πολιτών. Στην Ευρωπαϊκή Ένωση, οι απαιτήσεις λογοδοσίας και οι νομικές προϋποθέσεις προστατεύουν τα δεδομένα και τα δικαιώματα των πολιτών, αλλά δεν υπάρχει παγκόσμιο η ενιαίο πλαίσιο για τη ρύθμιση των τεχνολογιών αυτών. Η ανάγκη για καθορισμό νομικού πλαισίου είναι σημαντική, ενώ η πρόταση της ΕΕ για την Πράξη για την Τεχνητή Νοημοσύνη αναδεικνύει συγκρούσεις και κοινά σημεία με το ποινικό δίκαιο. Είναι ζωτικής σημασίας η αξιολόγηση των επιπτώσεων στα δικαιώματα και η διασφάλιση διαφάνειας και ελέγχου στη χρήση των τεχνολογιών αυτών.
description: Επιθεώρηση Δικαίου Πληροφορικής, Vol 5, No 1 (2024)
"Translingual Shakespeare: An Afterword," Shakespeare in Succession: Translation and Time, ed. Michael Saenger and Sergio Costola (Montreal: McGill-Queen's University Press, 2023), 298-307
Creators: name: Joubin, Alexa Alice
Publisher: name: McGill-Queen's University Press
Year: 2023
Subjects: subject: Postcolonialism
subject: Translations
subject: Feature films
subject: Shakespeare, William, 1564-1616
subject: Film adaptations

description: Literary translations work with, rather than out of, the space between languages. Translations evolve not only across linguistic and cultural borders but also across time. It is notable that Shakespeare's own play texts feature translational properties that can be amplified in translation. This translingual property makes Shakespeare's text inherently translational in the dramaturgical and gestural senses. A frequently stated myth is that Shakespearean drama is all about its poetic language, and adaptations in another language would violate the "original." The history of performance and reception in and beyond the Anglophone world suggests otherwise. Literary translations rely on, and amplify, the translingual property of languages. Translingual echoes occur when semantically linked phrases mean similar but not identical things in more than one language. Even English-language performances engage in translational behaviors, because audiences would find many scenes confusing without seeing the actors performing them. In our times, most audiences encounter Shakespeare in truncated, often translational, forms, such as short video clips, memes, or quotes. This cross-fertilization and mobility are the norms, not the exceptions. Translation studies contribute site-specific epistemologies to our understanding of what Shakespeare means in different locations and in different times.
A 14-year influenza reinfection surveillance in Chongqing, China: A retrospective analysis
Creators: name: Wang, Ju
name: Xiong, Yu
name: Li, Baisong
name: Yang, Jule
name: Xiao, Dayong
name: Fu, Xiaoqing
name: Long, Jiang
name: Qi, Li
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Influenza poses a significant medical burden and has the potential to cause global pandemics. To better understand the epidemiological characteristics of influenza reinfections and identify factors associated with an increased risk of reinfection, we analyzed influenza data from 2010 to 2023 obtained from the National Notifiable Infectious Disease Reporting Information System in Chongqing, China. The Andersen-Gill model was used to evaluate the association between demographic characteristics and the risk of reinfection. A total of 676,811.47 person-years were observed, with a median time to reinfection of 9.40 months. The log-rank test revealed significant differences in reinfection probability by sex, age, occupation, and residence (p < .001). Independent risk factors for influenza reinfection included male sex (adjusted hazard ratio [aHR]: 1.026, 95% confidence interval [CI]: 1.004–1.049), age ≤ 5 years (aHR: 4.645, 95% CI: 4.292–5.027), 6–18 years (aHR: 3.891, 95% CI: 3.574–4.235), age 46–64 years (aHR: 1.336, 95% CI: 1.158–1.541), and age ≥ 65 years (aHR: 2.946, 95% CI: 2.533–3.426), urban residency (aHR: 1.353, 95% CI: 1.315–1.391), and preschool-aged children (aHR: 2.103, 95% CI: 1.830–2.416). Influenza reinfection in Chongqing is relatively common and significantly associated with several key factors, including male sex, age ≤ 18 or > 45 years, preschool-aged children, and urban residency. These findings underscore the importance of tailored public health strategies, particularly promoting influenza vaccination among at-risk groups, to protect vulnerable populations from reinfection. Future studies are needed to refine influenza prevention measures for at-risk individuals, especially those susceptible to reinfection.
Μετασύμπαν (metaverse) και προστασία προσωπικών δεδομένων
Creators: name: Καμπά, Ζαμίλε- Ειρήνη
Publisher: name: Επιθεώρηση Δικαίου Πληροφορικής
Year: 2024

description: Στη μελέτη αυτή εξετάζεται η συμβατότητα και η δυνατότητα εφαρμογής του Γενικού Κανονισμού Προστασίας Δεδομένων στο εικονικό περιβάλλον του μετασύμπαντος (metaverse). Η έντονη συζήτηση γύρω από αυτό το εικονικό περιβάλλον τα τελευταία χρόνια, καθώς και οι προβληματισμοί που τίθενται σε σχέση με την προστασία των προσωπικών δεδομένων των χρηστών καθιστούν αναγκαία την εκ των προτέρων πρόβλεψη προστασίας τους. Γίνεται μία προσπάθεια περιγραφής του περιβάλλοντος αυτού και στη συνέχεια η παρούσα εστιάζει σε δύο σημεία σε σχέση με την επεξεργασία δεδομένων προσωπικού χαρακτήρα των χρηστών. Το πρώτο σχετίζεται με το ερώτημα ποιος ή ποιοι θα είναι υπέυθυνος/οι επεξεργασίας σε μία τέτοια πλατφόρμα και το δεύτερο με την επεξεργασία βιομετρικών δεδομένων και την κατάρτιση προφίλ και προτείνονται σχήματα που επιτρέπουν την εφαρμογή των διατάξεων του ΓΚΠΔ στο μετασύμπαν. Στο τέλος της παρούσης, τίθενται και κάποια περαιτέρω ανοιχτά ερωτήματα σε σχέση με την εφαρμογή του ΓΚΠΔ στο μετασύμπαν, αναδεικνύοντας την ανάγκη να στραφεί ο νομικός κόσμος προς την επίλυση αυτών.
description: Επιθεώρηση Δικαίου Πληροφορικής, Vol 5, No 1 (2024)
Η Κυβερνοασφάλεια και τα Προσωπικά Δεδομένα
Creators: name: Τσουκαλάς, Αναστάσιος
Publisher: name: Επιθεώρηση Δικαίου Πληροφορικής
Year: 2024

description: Η ραγδαία τεχνολογική εξέλιξη και η εκθετικά αυξανόμενη χρήση του διαδικτύου έχουν αναγάγει τις έννοιες της ιδιωτικής ζωής και της προστασίας των δεδομένων σε θέμα μείζονος ανησυχίας. Η συλλογή και αποθήκευση προσωπικών δεδομένων από παρόχους υπηρεσιών, διαχειριστές ιστότοπων, εφαρμογών και πλατφορμών κοινωνικής δικτύωσης, με στόχο την παροχή εξατομικευμένων υπηρεσιών, εγείρει εύλογα ερωτήματα σχετικά με την επάρκεια των μέτρων προστασίας των δεδομένων. Ωστόσο, η απουσία επαρκών εγγυήσεων για την προστασία των δεδομένων θέτει σε κίνδυνο την ασφάλεια των πληροφοριών, ενθαρρύνοντας παράλληλα την άνθηση εγκληματικών δραστηριοτήτων με ψηφιακή βάση σε παγκόσμια κλίμακα. Υπό το πρίσμα των ανωτέρω, η Ευρωπαϊκή Ένωση αναγνωρίζοντας την ανάγκη για μια ισχυρή και αξιόπιστη στρατηγική για την ασφάλεια στον κυβερνοχώρο, ώστε να διασφαλιστεί η εμπιστοσύνη στον κυβερνοχώρο και, κατά συνέπεια, να ενισχυθούν τα οφέλη από την καινοτομία, τη συνδεσιμότητα και την αυτοματοποίηση, διασφαλίζοντας τα θεμελιώδη δικαιώματα και ελευθερίες, συμπεριλαμβανομένων των δικαιωμάτων στην ιδιωτική ζωή και στην προστασία των προσωπικών δεδομένων.
description: Επιθεώρηση Δικαίου Πληροφορικής, Vol 5, No 1 (2024)
Visual analysis of the research frontiers, hotspots and development trends of immunization programs for women and children
Creators: name: Zhang, Jiachen
name: Zhang, Yani
name: Zhang, Litao
name: Wang, Jiaxing
name: Qu, Xinheng
name: Li, Mu
name: Zhang, Ruochen
name: Zhang, Bo
name: Zhang, Yuqing
name: Zhou, Jianping
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: The objective of this study is to gain insight into the current research frontiers, hotspots, and development trends in the field of immunization programs for women and children, and to provide scientific guidance and reference for follow-up research. Based on all the original research papers related to the research on immunization programs for women and children in the Web of Science Core Collection (WoSCC) database, bibliometric studies and visual analysis were carried out to explore the research frontiers, hotspots and development trends, and to analyze the risk factors affecting the vaccination coverage of immunization programs for women and children. Eight hundred forty-three papers obtained from 1,552 institutions in 96 countries/regions from January 1950 to August 2024, coauthored by 4,343 authors. With the largest number of papers published in the United States (408), Centers for Disease Control & Prevention – USA (169), Stokley S (15), and Pediatrics (143). The research frontiers of this discipline area mainly involve risk factors affecting the vaccination coverage of immunization programs for women and children, epidemiological surveillance, intervention research, changes in medical burden, adverse reactions, and vaccine development. Research hotspots mainly include measles, vaccine hesitancy, human papillomavirus, coverage, and pregnant women. The findings of the study informed policymakers, public health experts and researchers about the potential for modifying and improving policy systems and interventions related to the immunization programs for women and children. This had important implications for digital transformation and innovative research in health care providers’ clinical practice for the immunization programs for women and children.
Η εκτίμηση αντικτύπου στην προστασία προσωπικών δεδομένων: Μεθοδολογία και εφαρμογή σε συστήματα Τεχνητής Νοημοσύνης
Creators: name: Κωνσταντής, Νικόλαος
Publisher: name: Επιθεώρηση Δικαίου Πληροφορικής
Year: 2024

description: Στην παρούσα μελέτη αναλύεται η Εκτίμηση Αντικτύπου σχετικά με την Προστασία Προσωπικών Δεδομένων (ΕΑΠΔ) και συγκεκριμένα σε ποιες περιπτώσεις καθίσταται υποχρεωτική. Επιπλέον απαριθμούνται οι μεθοδολογικές προσεγγίσεις καθώς και τα βήματα που πρέπει να ακολουθηθούν κατά την εκπόνηση μιας ΕΑΠΔ. Στη συνέχεια αναφέρονται οι νομοθετικές εξελίξεις σε Ευρώπη και Ελλάδα σε σχέση με την Τεχνητή Νοημοσύνη (ΤΝ). Μέσα από αυτή την ανάλυση ανακύπτει το ζήτημα αν στα συστήματα που βασίζονται σε ΤΝ, η υιοθέτηση ενός συστήματος πιο εξελιγμένου από την ΕΑΠΔ, είναι αναγκαίο και απαραίτητο. Σε αυτό το ερώτημα απαντά τόσο ο Ν.4961/2022 με την υιοθέτηση της αλγοριθμικής εκτίμησης αντικτύπου όσο και η πρόσφατα νομοθετικά κατοχυρωμένη Πράξη για την ΤΝ.
description: Επιθεώρηση Δικαίου Πληροφορικής, Vol 5, No 1 (2024)
"Collaborative Rhizomatic Learning and Global Shakespeares," Reimagining Shakespeare Education: Teaching and Learning through Collaboration, ed. Liam E. Semler, Claire Hansen, and Jacqueline Manuel (Cambridge University Press, 2023), 225-238
Creators: name: Joubin, Alexa Alice
Publisher: name: Cambridge University Press
Year: 2023
Subjects: subject: Teaching
subject: Digital humanities
subject: Translations
subject: Social justice--Study and teaching
subject: Globalization
subject: Shakespeare, William, 1564-1616

description: Collaborative learning as a pedagogical method effectively reflects the communal character of the performing arts. By creating knowledge about Shakespearean performance collaboratively, students and educators lay claim to the ethics and ownership of that knowledge, an act that is particularly urgent and meaningful in the age of COVID-19 when we need to rebuild sociality. :::

 This chapter demonstrates how communal writing assignments and digital, video-based pedagogy turn textual and performative variants in Shakespeare's plays into a cluster of inclusive narratives for critical analysis. Shakespeare is no longer a white canon with culturally predetermined meanings. :::

 Through collaborative annotations of textual variants, this pedagogy encourages students to claim Shakespeare's language rather than aiming for interpretations that are gratuitous or merely politically correct. :::

 Working in tandem with collaborative textual analysis is video-centric collaboration. By turning a large number of performance versions into common objects of study, my digital video project makes links between adaptations that were previously regarded as distinct. In pedagogical contexts, the malleability of digital video puts play texts and performances to work in an interactive environment. :::

 Online performance video archives can encourage user curation and interaction with other forms of cultural records. In practice, this redistributes the power of collecting, re-arranging and archiving cultural records away from a centralised authority to the hands of student users. :::
Παρατηρήσεις στην απόφαση ΔΕΕ της 22ης Νοεμβρίου 2022, συνεκδικαζόμενες υποθέσεις С 37-20 και С 601-20 (1)
Creators: name: Ποντικόπουλος, Χαράλαμπος
Publisher: name: Επιθεώρηση Δικαίου Πληροφορικής
Year: 2024

description: Ο συγγραφέας σχολιάζει την απόφαση της 22.11.2022 του ΔΕΕ που θέτει ζητήματα σχετικά με τους περιορισμούς που απαιτείται να τεθούν (σύμφωνα με το άρθρο 5 παρ. 1 στοιχεία ά έως ΄γ του ΓΚΠΔ) στη δημόσια πρόσβαση του ευρύτερου κοινού στις πληροφορίες σχετικά με τους πραγματικούς δικαιούχους των εταιρειών και άλλων νομικών οντοτήτων
description: Επιθεώρηση Δικαίου Πληροφορικής, Vol 5, No 1 (2024)
Okul Öncesi Öğretmenlerinin Teknoloji Tutumları ve Psikolojik Dayanıklılık Düzeyleri Arasındaki İlişkinin İncelenmesi
Creators: name: AKDAĞ, İlyas
Publisher: name: Zenodo
Year: 2025

description: Araştırma, Denizli Çameli ilçesindeki okul öncesi öğretmenlerinin teknoloji kullanım tutumları ile psikolojik dayanıklılık düzeyleri arasındaki ilişkiyi incelemiştir. 130 okul öncesi öğretmeni araştırmanın evrenini oluştururken, 30 öğretmen basit seçkisiz örnekleme yöntemiyle seçilmiştir. Psikolojik Dayanıklılık ve Teknoloji Tutum ölçekleri kullanılarak elde edilen veriler SPSS 22 programı ile analiz edilmiştir. Bulgular, öğretmenlerin teknoloji kullanım tutumlarının cinsiyet, yaş, hizmet süresi ve eğitim düzeyi gibi faktörlerle ilişkili olduğunu göstermektedir. Kadın öğretmenlerin, genç ve daha yüksek eğitim düzeyine sahip olanların teknoloji kullanım tutumlarının daha yüksek olduğu tespit edilmiştir. Ayrıca, öğretmenlerin psikolojik dayanıklılık algıları ile teknoloji tutumları arasında ilişki olduğu belirlenmiştir. Bu bulgular, okul öncesi eğitimde teknoloji kullanımının ve öğretmenlerin psikolojik dayanıklılığının önemini vurgulamakta ve ilgili politika ve uygulamalara yol göstermektedir. Araştırmanın sınırlamaları ve gelecek çalışmalara öneriler de dikkate alınarak, konuyla ilgili daha derinlemesine araştırmaların yapılması önerilmektedir
Additional file 8 of Cannulated screws versus dynamic hip screw versus hemiarthroplasty versus total hip arthroplasty in patients with displaced and non-displaced femoral neck fractures: a systematic review and frequentist network meta-analysis of 5703 patients
Creators: name: Ramadanov, Nikolai
name: Jóźwiak, Katarzyna
name: Hauptmann, Michael
name: Lazaru, Philip
name: Marinova-Kichikova, Polina
name: Dimitrov, Dobromir
name: Becker, Roland
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 8: Forest plot of Harris Hip Score ≤ 6 months postoperatively (displaced femoral neck fractures only). CS, cannulated screw; DHS, dynamic hip screw; HA, hemiarthroplasty; THA, total hip arthroplasty; SD, standard deviation; MD, mean difference; CI, confidence interval.
Simultaneous quantification of five bacterial and plant toxins from complex matrices using a multiplexed fluorescent magnetic suspension assay
Creators: name: Pauly, Diana
name: Kirchner, Sebastian
name: Stoermann, Britta
name: Schreiber, Tanja
name: Kaulfuss, Stefan
name: Schade, Rüdiger
name: Zbinden, Reto
name: Avondet, Marc-André
name: Dorner, Martin
name: Dorner, Brigitte
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2009
Subjects: subject: Animals
subject: Mice
subject: Antibodies
subject: Time Factors
subject: Enzyme-Linked Immunosorbent Assay
subject: Reproducibility of Results
subject: Inbred BALB C
subject: Bacterial Toxins/analysis
subject: Fluorescence
subject: Monoclonal/immunology
subject: Antibody Specificity
subject: Bacterial Toxins/immunology
subject: Food Analysis
subject: Immunization
subject: Limit of Detection
subject: Magnetics
subject: Plants/chemistry
subject: Spectrometry
subject: Suspensions
subject: Toxins
subject: Biological/analysis
subject: Biological/immunology
subject: 610 Medizin

description: Proteotoxins such as ricin, abrin, botulinum neurotoxins type A and B (BoNT/A, BoNT/B) and staphylococcal enterotoxin B (SEB) are regarded as potential biological warfare agents which could be used for bioterrorism attacks on the food chain. In this study we used a novel immunisation strategy to generate high-affinity monoclonal and polyclonal antibodies against native ricin, BoNT/A, and BoNT/B. The antibodies were used along with antibodies against SEB and abrin to establish a highly sensitive magnetic and fluorescent multiplex bead array with excellent sensitivities between 2 ng/L and 546 ng/L from a minimal sample volume of 50 µL. The assay was validated using 20 different related analytes and the assay precision was determined. Advancing the existing bead array technology, the novel magnetic and fluorescent microbeads proved amenable to enrichment procedures, by further increasing sensitivity to 0.3–85 ng/L, starting from a sample volume of 500 µL. Furthermore, the method was successfully applied for the simultaneous identification of the target toxins spiked into complex food matrices like milk, baby food and yoghurt. On the basis of our results, the assay appears to be a good tool for large-scale screening of samples from the food supply chain.
Impact of FcRn antagonism on vaccine-induced protective immune responses against viral challenge in COVID-19 and influenza mouse vaccination models
Creators: name: Warang, Prajakta
name: Singh, Gagandeep
name: Moshir, Mahan
name: Binazon, Ornella
name: Laghlali, Gabriel
name: Chang, Lauren A.
name: Wouters, Heidi
name: Vanhoenacker, Peter
name: Notebaert, Margo
name: Elhemdaoui, Nadia
name: Augustynková, Kateřina
name: Steeland, Sophie
name: Ulrichts, Peter
name: Baumeister, Judith
name: Schotsaert, Michael
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Antagonism of the neonatal Fc receptor through an engineered antibody Fc fragment, such as efgartigimod, results in a decrease in immunoglobulin G levels. This approach is being evaluated as a therapeutic strategy for the treatment of IgG-mediated autoimmune diseases. Our goal was to evaluate the impact of mFc-ABDEG, a mouse-adapted antibody Fc fragment with a mode of action highly similar to efgartigimod, on vaccine-induced protective immune responses against viral infections. Therefore, mouse vaccination models for COVID-19 and influenza were employed, utilizing an mRNA COVID-19 vaccine (COMIRNATY) and an adjuvanted, inactivated quadrivalent influenza vaccine (Seqirus+AddaVax), respectively. In both models, vaccination induced robust humoral responses. As expected, animals treated with mFc-ABDEG had lower levels of virus-specific IgG, while virus-specific IgM responses remained unaffected. The COVID-19 vaccine induced a strong Th1-type T cell response irrespective of mFc-ABDEG treatment. Influenza vaccination resulted in a poor T cell induction, regardless of mFc-ABDEG treatment, due to the Th2-biased response that inactivated influenza vaccines typically induce. Importantly, mFc-ABDEG treatment had no effect on protective immunity against live viral challenges in both models. Vaccinated animals treated with mFc-ABDEG were equally protected as the non-treated vaccinated controls. These non-clinical data demonstrate that FcRn antagonism with mFc-ABDEG did not affect the generation of vaccine-induced protective humoral and cellular responses, or protection against viral challenges. These data substantiate the clinical observations that, although IgG titers were reduced, FcRn antagonism with efgartigimod did not impair the ability to generate new specific IgG responses, regardless of the timing of vaccination.
CRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses
Creators: name: Hrincius, Eike R.
name: Wixler, Viktor
name: Wolff, Thorsten
name: Wagner, Ralf
name: Ludwig, Stephan
name: Ehrhardt, Christina
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2010
Subjects: subject: Cell Line
subject: Humans
subject: Animals
subject: Viral Nonstructural Proteins/metabolism
subject: JNK Mitogen-Activated Protein Kinases/metabolism
subject: Protein Binding
subject: Activating Transcription Factor 2
subject: Adaptor Proteins
subject: Signal Transducing/metabolism
subject: Apoptosis
subject: Chick Embryo
subject: Dogs
subject: Influenza A virus/growth & development
subject: Nuclear Proteins/metabolism
subject: Proto-Oncogene Proteins c-crk/metabolism
subject: 610 Medizin

description: The non-structural protein 1 (A/NS1) of influenza A viruses (IAV) harbours several src-homology domain (SH) binding motifs that are required for interaction with cellular proteins. The SH3 binding motif at aa212-217 [PPLPPK] of A/NS1 was shown to be essential for binding to the cellular adaptor proteins CRK and CRKL. Both regulate diverse cellular effector pathways, including activation of the MAP-kinase JNK that in turn mediates antiviral responses to IAV infection. By studying functional consequences of A/NS1–CRK interaction we show here that A/NS1 binding to CRK contributes to suppression of the antiviral-acting JNK–ATF2 pathway. However, only IAV that encode an A/NS1-protein harbouring the CRK/CRKL SH3 binding motif PPLPPK were attenuated upon downregulation of CRKI/II and CRKL, but not of CRKII alone. The PPLPPK site-harbouring candidate strains could be discriminated from other strains by a pronounced viral activation of the JNK–ATF2 signalling module that was even further boosted upon knock-down of CRKI/II. Interestingly, this enhanced JNK activation did not alter type-I IFN-expression, but rather resulted in increased levels of virus-induced cell death. Our results imply that binding capacity of A/NS1 to CRK/CRKL has evolved in virus strains that over-induce the antiviral acting JNK–ATF2 signalling module and helps to suppress the detrimental apoptosis promoting action of this pathway.
Notes relative to the treatment of Rubiaceae tribe VIII. Coffeeae in Flore d'Afrique centrale
Creators: name: Robbrecht, Elmar
Publisher: name: Meise Botanic Garden
Year: 2024
Subjects: Empogona
Belonophora
Sericanthe
Tricalysia
Argocoffeopsis
Coffea
Psilanthus
Rwanda
Burundi
Democratic Republic of the Congo
Flora
Plants

description: These notes explain some of the taxonomic decisions made for the treatment of some Coffeeae taxa in Flore d’Afrique centrale (Robbrecht et al. 2024), the rationale being too long for being included in the Flore itself.
Cases of community-acquired meticillin-resistant Staphylococcus aureus in an asylum seekers centre in Germany, November 2010
Creators: name: Dudareva, Sandra
name: Barth, A.
name: Paeth, K.
name: Krenz-Weinreich, A.
name: Layer, Franziska
name: Deleré, Yvonne
name: Eckmanns, Tim
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2011
Subjects: subject: Adolescent
subject: Humans
subject: Female
subject: Germany
subject: Male
subject: Middle Aged
subject: Animals
subject: Adult
subject: Aged
subject: Polymerase Chain Reaction/methods
subject: Methicillin Resistance
subject: Contact Tracing
subject: Young Adult
subject: Community-Acquired Infections/microbiology
subject: Methicillin-Resistant Staphylococcus aureus/isolation & purification
subject: Staphylococcal Infections/microbiology
subject: Methicillin-Resistant Staphylococcus aureus/genetics
subject: Bacterial Toxins/isolation & purification
subject: Community-Acquired Infections/transmission
subject: Exotoxins/isolation & purification
subject: Furunculosis/diagnosis
subject: Leukocidins/isolation & purification
subject: Molecular Typing
subject: Nose/microbiology
subject: Refugees
subject: Somalia/ethnology
subject: Staphylococcal Infections/diagnosis
subject: Staphylococcal Infections/ethnology
subject: 610 Medizin

description: In an asylum seeker centre in Schleswig-Holstein, a resident was diagnosed with furuncle caused by a Panton-Valentine leukocidine (PVL)-positive community- acquired meticillin-resistant Staphylococcus aureus (CA-MRSA). As a result of active case finding, 232 of 427 persons (54% of all residents) were screened for MRSA and two further PVL-positive CA-MRSA cases were identified.
Additional file 2 of Network analysis of maternal parenting practices and adolescent mental health problems: a longitudinal study
Creators: name: Sun, Xinlu
name: Yuan, Ting
name: Chen, Feifei
name: Li, Yan
name: Jiang, Nengzhi
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Science Policy
Mental Health

description: Supplementary Material 2
Numerical Simulations of Gas Discharges for Flow Control Applications
Creators: name: Piskin, Tugba
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerodynamics (excl. hypersonic aerodynamics)
Plasma physics; fusion plasmas; electrical discharges
Applications in physical sciences
Computational methods in fluid flow, heat and mass transfer (incl. computational fluid dynamics)

description: In the aerospace industry, gas discharges have gained importance with the exploration of their performance and capabilities for flow control and combustion. Tunable properties of plasma make gas discharges efficient tools for various purposes. Since the scales of plasma and the available technology limit the knowledge gained from experimental studies, computational studies are essential to understand the results of experimental studies. The temporal and spatial scales of plasma also restrict the numerical studies. It is a necessity to use an idealized model, in which enough physics is captured, while the computational costs are acceptable.

In this work, numerical simulations of different low-pressure gas discharges are presented with a detailed analysis of the numerical approach. A one moment model is employed for DC glow discharges and nanosecond-pulse discharges. The cheap-est method regarding the modeling and simulation costs is chosen by checking the requirements of the fundamental processes of gas discharges. The verification of one-moment 1-D glow discharges with constant electron temperature variation is achieved by comparing other computational results.

The one moment model for pulse discharge simulation aims to capture the information from the experimental data for low-pressure argon discharges. Since the constant temperature assumption is crude, the local field approximation is investigated to obtain the data for electron temperature. It was observed that experimental data and computational data do not match because of the stagnant decay of electron number densities and temperatures. At the suggestion of the experimental group, water vapor was added as an impurity to the plasma chemistry. Although there was an improvement with the addition of water vapor, the results were still not in good agreement with experiment.

The applicability of the local field approximation was investigated, and non-local effects were included in the context of an averaged energy equation. A 0-D electron temperature equation was employed with the collision frequencies obtained from the local field approximation. It was observed that the shape of the decay profiles matched with the experimental data. The number densities; however, are less almost an order of magnitude.

As a final step, the two-moment model, one-moment model plus thermal electron energy equation, was solved to involve non-local effects. The two-moment model allows capturing of non-local effects and improves agreement with the experimental data. Overall, it was observed that non-local regions dominate low-pressure pulsed discharges. The local field approximation is not adequate to solve these types of discharges.
Alexa Alice Joubin and Elizabeth Rivlin, "Remedial Uses of Shakespeare," Shakespeare and Cultural Appropriation, ed. Vanessa I. Corredera, L.Monique Pittman, Geoffrey Way (Routledge, 2023), pp. 222-233
Creators: name: Joubin, Alexa Alice
Publisher: name: Routledge
Year: 2023
Subjects: subject: Novels
subject: Nostalgia
subject: Queer theory
subject: Ethics
subject: Shakespeare, William, 1564-1616
subject: Film adaptations

description: This chapter argues that cultural appropriation can be an exploitative act but need not be; it all depends on what users do with Shakespeare. Due to the unequal status of the parties engaged in appropriative exchange, some appropriations deploy Shakespeare to protect conventional power structures. Appropriations are rarely negotiated on a level playing field, especially when it comes to Shakespeare, because of the canon's long history of association with cultural elites and prestige. Cultural appropriation can also have subversive and counter-hegemonic effects. Marginalized agents have the power to expose and correct power imbalances. In other words, we addresses a wide range of intercultural and global appropriations of Shakespeare. Our study also complicates any simple definition of how cultural appropriation works and what ethical effects it might produce. Not only does "remedial" have diverging definitions, but it is also proximate to "remediation," in the sense given it by Jay David Bolter and Richard Grusin, namely, "the representation of one medium in another." If we conjoin this definition to acts of remedying or correcting, the implication is that such acts occur in-and as a result of-the process of media transformation. It is important to teach cultural appropriation, because in studying how authors, theater directors, and filmmakers appropriate Shakespeare to meet varied cultural priorities, students come to recognize themselves as potential agents of appropriation, with attendant power and responsibility.
AI-Based Decision Support Systems in Industry 4.0, A Review
Creators: name: Soori, Mohsen
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 401407
subject: Manufacturing management

description: The development of modern technologies such as the Internet of Things (IoT), cloud computing, and artificial intelligence (AI) resulted in a new era of industrial automation and data interchange, which is known as Industry 4.0. AI-based decision support systems (DSS) play a crucial role in this paradigm by enhancing the integration and processing of IoT and sensor data to optimize operations, improve productivity, and enable predictive maintenance. Machine learning models analyze production data and visual inspections to identify defects and ensure product quality. This review paper explores the transformative role of AI in enhancing DSS within Industry 4.0, highlighting key technologies including machine learning, deep learning, and natural language processing. It explores a number of applications, including supply chain optimization, energy management, predictive maintenance, quality control, and production planning, showing how AI-driven DSS can significantly boost operational dependability, cut costs, and improve efficiency. The article also discusses the AI-based DSS's architecture and implementation, with a focus on data management, user interface design, and IoT integration. Furthermore, it examines the challenges related to data quality, technical integration, and human factors, offering potential solutions and strategies for effective deployment. The study highlights the continued development of AI technologies and their potential to support autonomous decision-making in industrial settings by identifying new trends and areas for further research. This comprehensive review aims to provide valuable insights for researchers and practitioners, fostering a deeper understanding of the capabilities and future potential of AI-based DSS in Industry 4.0.
Yöneticilerin Dijital Okuryazarlık Düzeylerinin İncelenmesi
Creators: name: GÜÇLÜ, Aysun
Publisher: name: Zenodo
Year: 2025

description: Bu araştırmada, okul yöneticilerinin dijital okuryazarlık algılarının belirlenmesi ve değerlendirilmesi amaçlanmıştır. Günümüzde dijital teknolojinin eğitimdeki önemi giderek artmaktadır ve bu bağlamda, okul yöneticilerinin dijital okuryazarlık düzeylerinin anlaşılması önem arz etmektedir. Araştırmanın temel amacı, okul yöneticilerinin dijital okuryazarlık düzeylerini tanımlamak ve bu düzeyler arasındaki potansiyel farklılıkları ortaya koymaktır. Betimsel bir araştırma olan bu çalışma, mevcut durumu tanımlama ve belirli bir konuyu detaylı bir şekilde analiz etme amacı gütmektedir. Araştırmanın evrenini İstanbul ili Küçükçekmece ilçesinde yaşayan 953 öğretmen oluştururken, örneklemi basit seçkisiz örnekleme yöntemiyle seçilen 281 öğretmen oluşturmaktadır. Bu örneklem, ilçedeki farklı okullardan ve farklı branşlardan öğretmenleri kapsayacak şekilde dengeli bir şekilde seçilmiştir. Araştırmanın verileri, 2023-2024 eğitim-öğretim yılı bahar döneminde, nisan ve mayıs ayları arasında Google Formlar aracılığıyla çevrimiçi olarak toplanmıştır. Elde edilen veriler, istatistiksel analizlerle değerlendirilmiş ve sonuçlar elde edilmiştir. Araştırma bulgularına göre bu çalışma, katılımcıların genel dijital okuryazarlık düzeylerini cinsiyet, medeni durum, mesleki kıdem ve eğitim düzeyi değişkenlerine göre analiz etmiştir. Bulgular, katılımcıların genel olarak orta seviyede dijital okuryazarlık becerilerine sahip olduklarını göstermektedir. Kadın ve erkek katılımcılar arasında dijital okuryazarlık düzeyleri açısından anlamlı bir fark bulunmamıştır (t = -0.287, p = 0.603). Evli ve bekar katılımcılar arasında da dijital okuryazarlık düzeyleri açısından anlamlı bir fark tespit edilmemiştir (t = -0.783, p = 0.132). Mesleki kıdem grupları arasında yapılan karşılaştırmada da (t = 0.559, p = 0.643), dijital okuryazarlık düzeyleri açısından istatistiksel olarak anlamlı bir farklılık bulunmamıştır. Son olarak, lisans ve lisansüstü eğitim düzeyine sahip katılımcıların dijital okuryazarlık düzeyleri arasında da (t = 1.706, p = 0.187) istatistiksel olarak anlamlı bir fark saptanmamıştır.
IMAGE AND VIDEO QUALITY ASSESSMENT WITH APPLICATIONS IN FIRST-PERSON VIDEOS
Creators: name: Bai, Chen
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Electrical engineering not elsewhere classified

description: First-person videos (FPVs) captured by wearable cameras provide a huge amount of visual data. FPVs have different characteristics compared to broadcast videos and mobile videos. The video quality of FPVs are influenced by motion blur, tilt, rolling shutter and exposure distortions. In this work, we design image and video assessment methods applicable for FPVs.
Our video quality assessment mainly focuses on three quality problems. The first problem is the video frame artifacts including motion blur, tilt, rolling shutter, that are caused by the heavy and unstructured motion in FPVs. The second problem is the exposure distortions. Videos suffer from exposure distortions when the camera sensor is not exposed to the proper amount of light, which often caused by bad environmental lighting or capture angles. The third problem is the increased blurriness after video stabilization. The stabilized video is perceptually more blurry than its original because the masking effect of motion is no longer present.
To evaluate video frame artifacts, we introduce a new strategy for image quality estimation, called mutual reference (MR), which uses the information provided by overlapping content to estimate the image quality. The MR strategy is applied to FPVs by partitioning temporally nearby frames with similar content into sets, and estimating their visual quality using their mutual information. We propose one MR quality estimator, Local Visual Information (LVI), that estimates the relative quality between two images which overlap.
To alleviate exposure distortions, we propose a controllable illumination enhancement method that adjusts the amount of enhancement with a single knob. The knob can be controlled by our proposed over-enhancement measure, Lightness Order Measure (LOM). Since the visual quality is an inverted U-shape function of the amount of enhancement, our design is to control the amount of enhancement so that the image is enhanced to the peak visual quality.
To estimate the increased blurriness after stabilization, we propose a visibility-inspired temporal pooling (VTP) mechanism. VTP mechanism models the motion masking effect on perceived video blurriness as the influence of the visibility of a frame on the temporal pooling weight of the frame quality score. The measure for visibility is estimated as the proportion of spatial details that is visible for human observers.
Herausforderungen an die Gesundheitsforschung für eine alternde Gesellschaft am Beispiel „Multimorbidität“
Creators: name: Scheidt-Nave, Christa
name: Richter, S.
name: Fuchs, Judith
name: Kuhlmey, A.
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2010
Subjects: subject: Multimorbidität
subject: Gebrechlichkeit
subject: Versorgungsforschung
subject: Altern
subject: Bevölkerung
subject: Aging
subject: Population
subject: Multimorbidity
subject: Frailty
subject: Health care services research
subject: 610 Medizin

description: Indem ein wachsender Anteil der Bevölkerung ein hohes Alter erreicht, ändern sich Krankheitsspektrum und Versorgungsbedarf. Besondere Herausforderungen für das Gesundheitssystem ergeben sich durch Mehrfacherkrankung (Multimorbidität) älterer Menschen. Im Gegensatz zu krankheitsspezifischen Endpunkten treten Funktion im Alltag und subjektive Ergebnisdimensionen wie selbstbestimmte Lebensführung (Autonomie), soziale Teilhabe und Lebensqualität als Präventions- und Behandlungsziel in den Vordergrund. Die Gesundheitsforschung hat die Aufgabe, auf die Bedürfnisse spezifischer Zielgruppen alter Menschen abgestimmte Präventions- und Versorgungsmodelle zu entwickeln. Entscheidend dabei ist die Stärkung von personalen, sozialen und organisatorischen Ressourcen. Voraussetzung hierfür sind genaue Kenntnisse zur Entwicklung und zum Verlauf des Krankheitsgeschehens und zu zentralen Einflussfaktoren auf der Grundlage epidemiologischer Beobachtungsstudien. Gezielte Maßnahmen sind in Interventions- und Evaluationsstudien auf Wirksamkeit, Wirkung und Wirtschaftlichkeit zu überprüfen. Der vom Bundesministerium für Bildung und Forschung (BMBF) initiierte Förderungsschwerpunkt „Gesundheit im Alter“ fördert insgesamt sechs Forschungsverbünde zum Thema Multimorbidität, die hier kurz vorgestellt werden.
PCV20 for the prevention of invasive pneumococcal disease in the Mexican pediatric population: A cost-effectiveness analysis
Creators: name: Huerta, José Luis
name: Ta, An
name: Vinand, Elizabeth
name: Torres, Gustavo Ivan
name: Wannaadisai, Warisa
name: Huang, Liping
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Science Policy

description: The introduction of a pneumococcal conjugate vaccine (PCV) covering 13 serotypes (PCV13) into the Mexican pediatric national immunization program (NIP) has substantially reduced the burden of pneumococcal disease (PD) since 2010. This study aimed to estimate the impact of replacing either PCV13 or 15valent PCV (PCV15) with 20-valent PCV (PCV20) in the Mexican pediatric NIP. A decision-analytic Markov model was developed to compare the cost-effectiveness of PCV20 versus lower-valent vaccines from a Mexican public health sector (payer) perspective over 10 years. Epidemiological and cost inputs were sourced from Mexican data. Direct and indirect vaccine effects were estimated using PCV13 clinical effectiveness, 7-valent PCV efficacy studies, and PCV13 impact data in Mexico. The estimated disease and cost impact of PCV20 was compared with PCV13 and PCV15, all under a 2 + 1 dosing schedule. A discount rate of 5% per annum was applied to costs and health outcomes. Model robustness was evaluated through sensitivity analyses, including deterministic sensitivity analysis (DSA), probabilistic sensitivity analysis (PSA), and additional scenario assessments. PCV20 was estimated to provide considerably more health benefits than both comparators by averting more cases of PD compared with both PCV13 and PCV15, as well as a total cost saving of over 10 billion Mexican pesos. The DSA, PSA, and scenario assessments confirmed minimal deviation from the base case. Therefore, the introduction of PCV20 (2 + 1) into the Mexican pediatric NIP is expected to reduce the burden of PD and medical costs compared with lower-valent alternatives.
HDR Images via IIIF Image API
Creators: name: Mahnke, Christian
Publisher: name: Zenodo
Year: 2024
Subjects: HDR
IIIF
Cultural Heritage
Digital Libraries
GLAM
Museums
Exhibitions
Digital Images
Digital humanities communication

description: Device displays have made progress the last decade, starting with ever increasing pixel densities, the focus has shifted to more colors (color spaces) and increased brightness. These developments allow the display of HDR content and browsers are also gradually supporting displaying it. What is not unusual for YouTube videos, can now also be used for images: Either to increase immersion, i.e. to make a cultural artefact more interesting, or to support scientific visualization. This presentation introduces the prototype for an IIIF Image API endpoint with UltraHDR tiles and explains the next steps: There is currently an initiative to specify how such HDR content can be transported via the Image API. In this context, it may also emerge that additional metadata is desirable in the Presentation API.
Suppressed Narrator, Silenced Victim in Adania Shibli’s Minor Detail
Creators: name: Nashef, Hania
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Palestinian Nakba, 1947-1948, in literature
subject: Palestinian Arabs
subject: Bedouins
subject: Genocide
subject: Forced migration

description: Although the systematic eviction of Palestinians from their homeland has been recorded at length since the establishment of the state of Israel in  948, the documentation has namely concerned itself with urban centers or villages. Expulsion and removal of marginalized communities, namely the Bedouins’, from their ancestral encampments or homes have been given scant coverage by main stream media or even academia. A nomadic life is often stigmatized by the notion of transience, and thus barely considered as valuable as other lives. Furthermore, the ownership and rights to the lands that nomadic people occupy are rarely recognized. In her latest novel, Minor Detail, Palestinian writer Adania Shibli traces the story of a Bedouin girl in 1949 and her brutal slaying at the hands of Zionist gangs through the narrative of a young West Bank woman from Ramallah, who becomes obsessed with uncovering the burial site of the slain girl. The nameless narrator in the book embarks on a journey in an attempt to unravel the circumstances behind the death of the nameless Bedouin girl; her expedition results in unearthing minor details relating to the ethnic cleansing of the girl’s tribe along with their silenced history. The novel evolves into a story of parallel lives, albeit 25 years apart. The Ramallah woman’s insistence in finding the exact place in which the atrocity was committed develops into a quest that is haunted by specters from the past. In this paper, I will argue that exposing the story of the Bedouin girl and her community not only allows the reader to reconstruct the marginalized lives of a people who were and remain part of the fabric of a disappearing country but is also an attempt at marking an absent life.