cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
L'herbier de force l'intertextualité botanique chez Jacques Ferron et Réjean Ducharme
Creators: name: Cullen, Heather
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Literature, Canadian (French).

description: Cette étude cherche à déterminer le fonctionnement des inscriptions narratives, discursives et thématiques de l'intertextualité botanique dans les oeuvres de Jacques Ferron et de Réjean Ducharme. Ces deux écrivains, par ailleurs très différents l'un de l'autre, partagent cependant une même pratique, celle d'insérer dans leurs écrits des citations et des emprunts tirés d'un traité botanique très célèbre au Québec: la Flore laurentienne (1935) du frère Marie-Victorin. L'oeuvre scientifique de cet ecclésiastique de renommée mondiale---fondateur, durant les années 1930, de l'Institut Botanique et du Jardin Botanique de Montréal---se trouve transformée dans son nouveau contexte fictionnel. À la lumière de l'éco-critique (nouvelle méthode d'approche du texte littéraire qui s'inspire de la critique intertextuelle et de la science de l'écologie), notre projet cherche à decouvrir comment Jacques Ferron et Réjean Ducharme, qui appartiennent à deux générations différentes d'écrivains, ont tous deux manifesté le même désir d'employer et de renouveler un herbier particulier. Nous étudierons les multiples moyens par lesquels Ferron et Ducharme ont donné à l'ouvrage de Marie-Victorin le statut de texte sacré, comme s'il s'agissait d'un herbier "de force".
title: Infecciones Intracraneales y Raquídeas
Creators: name: Stolowicz Wien, Carol
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: CT
subject: MR
subject: Emergency
subject: Education

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
- Revisar los hallazgos radiológicos en Tomografía Computarizada (TC) y/o Resonancia Magnética (RM) de los procesos infecciosos que afectan a la médula espinal,
el cerebro y las meninges. - Describir los patrones de diseminación habitual de las...
Homogeneous locally nilpotent derivations and affine ML-surfaces
Creators: name: Kolhatkar, Ratnadha
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Mathematics.

description: Let B = k[X0, X1, X2] be the polynomial ring in three variables over an algebraically closed field k of characteristic zero. We consider the homogeneous case of the problem of describing locally nilpotent derivations of B. Given integers a0, a1, a 2 satisfying gcd{a0, a 1, a2} = 1, we define a Z -grading g on B by declaring that Xi is homogeneous of degree ai (for i = 0, 1, 2). In this thesis, we give an explicit description of the g -homogeneous locally nilpotent derivations of B when the integers a0, a1, a2 are not pairwise relatively prime. In the case where a0, a1, a 2 are pairwise relatively prime, we characterize the kernels of g -homogeneous locally nilpotent derivations of B among all subalgebras of B. Now assume that k is an arbitrary field of characteristic zero. In the remainder of this thesis, we study properties of affine k-surfaces which have trivial Makar-Limanov invariant. In particular, we prove that such surfaces have only finitely many singular points. As an application, we also prove that a complete intersection surface with trivial Makar-Limanov invariant is normal; in particular, any hypersurface of the affine space A3k with trivial Makar-Limanov invariant is normal.
Supplementary document for Coherence effects on estimating two-point separation - 4920328.pdf
Creators: name: Liang, Kevin
name: Wadood, Sultan Abdul
name: Vamivakas, Nickolas
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplemental Material for the derivation of the density matrix, derivation of the spanning set of eigenvectors, and a comparison of the quantum FI with direct intensity measurements
What strategies do desk-based workers choose to reduce sitting time and how well do they work? Findings from a cluster randomised controlled trial 11 Medical and Health Sciences 1117 Public Health and Health Services
Creators: name: Stephens, Samantha K.
name: Eakin, Elizabeth G.
name: Clark, Bronwyn K.
name: Winkler, Elisabeth A.H.
name: Owen, Neville
name: Lamontagne, Anthony D.
name: Moodie, Marj
name: Lawler, Sheleigh P.
name: Dunstan, David W.
name: Healy, Genevieve N.
Publisher: name: Swinburne
Year: 2024

description: Background: Large amounts of sitting at work have been identified as an emerging occupational health risk, and findings from intervention trials have been reported. However, few such reports have examined participant-selected strategies and their relationships with behaviour change. Methods: The Stand Up Victoria cluster-randomised controlled trial was a workplace-delivered intervention comprising organisational, environmental and individual level behaviour change strategies aimed at reducing sitting time in desk-based workers. Sit-stand workstations were provided, and participants (n = 134; intervention group only) were guided by health coaches to identify strategies for the 'Stand Up', 'Sit Less', and 'Move More' intervention targets, including how long they would stand using the workstation. Three-month workplace sitting and activity changes (activPAL3-assessed total sitting, prolonged sitting (i.e., sitting ≥30 min continuously) and purposeful walking) were evaluated in relation to the number (regression analysis) and types of strategies (decision-tree analysis). Results: Over 80 different strategies were nominated by participants. Each additional strategy nominated for the 'Stand Up' intervention target (i.e. number of strategies) was associated with a reduction in prolonged sitting of 27.6 min/8-h workday (95% CI: -53.1, - 2.1, p = 0.034). Types of strategies were categorised into 13 distinct categories. Strategies that were task-based and phone-based were common across all three targets. The decision tree models did not select any specific strategy category as predicting changes in prolonged sitting ('Stand Up'), however four strategy categories were identified as important for total sitting time ('Sit Less') and three strategy categories for purposeful walking ('Moving More'). The uppermost nodes (foremost predictors) were nominating > 3 h/day of workstation standing (reducing total workplace sitting) and choosing a 'Move More' task-based strategy (purposeful walking). Conclusions: Workers chose a wide range of strategies, with both strategy choice and strategy quantity appearing relevant to behavioural improvement. Findings support a tailored and pragmatic approach to encourage a change in sitting and activity in the workplace. Evaluating participant-selected strategies in the context of a successful intervention serves to highlight options that may prove feasible and effective in other desk-based workplace environments. Trial registration: This trial was prospectively registered with the Australian New Zealand Clinical Trials register (ACTRN12611000742976) on 15 July 2011,
Supplementary document for Breaking Planar Symmetries by Single Layered Metasurface for Realizing Unique On-chip Chiroptical Effects - 4921885.pdf
Creators: name: MEHMOOD, MUHAMMAD QASIM
name: Naeem, Taimoor
name: Sarwar, Ahsan
name: Zubair, Muhammad
name: Tauqeer, Tauseef
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary Information
Vibrational Time Theory
Creators: name: Benaglia, Angelo
Publisher: name: Zenodo
Year: 2025

description: Este é um preprint de física teórica que propõe a Teoria Vibracional do Tempo (VTT), incluindo derivações formais, simulações e previsões que podem ser testadas observacionalmente. O trabalho complementa a relatividade geral e a mecânica quântica, visando uma unificação por meio do surgimento do tempo baseado em frequência.
The Three Hundred project: A large catalogue of theoretically modelled galaxy clusters for cosmological and astrophysical applications
Creators: name: Cui, Weiguang
name: Knebe, Alexander
name: Yepes, Gustavo
name: Pearce, Frazer
name: Power, Chris
name: Dave, Romeel
name: Arth, Alexander
name: Borgani, Stefano
name: Dolag, Klaus
name: Elahi, Pascal
name: Mostoghiu, Robert
name: Murante, Giuseppe
name: Rasia, Elena
name: Stoppacher, Doris
name: Vega-Ferrero, Jesus
name: Wang, Yang
name: Yang, Xiaohu
name: Benson, Andrew
name: Cora, Sofía A.
name: Croton, Darren
name: Sinha, Manodeep
name: Stevens, Adam R.H.
name: Vega-Martínez, Cristian A.
name: Arthur, Jake
name: Baldi, Anna S.
name: Cañas, Rodrigo
name: Cialone, Giammarco
name: Cunnama, Daniel
name: De Petris, Marco
name: Durando, Giacomo
name: Ettori, Stefano
name: Gottlöber, Stefan
name: Nuza, Sebastián E.
name: Old, Lyndsay J.
name: Pilipenko, Sergey
name: Sorce, Jenny G.
name: Welker, Charlotte
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 5101
subject: Astronomical sciences

description: We introduce the THE THREE HUNDRED project, an endeavour to model 324 large galaxy clusters with full-physics hydrodynamical re-simulations. Here we present the data set and study the differences to observations for fundamental galaxy cluster properties and scaling relations.We find that the modelled galaxy clusters are generally in reasonable agreement with observations with respect to baryonic fractions and gas scaling relations at redshift z = 0. However, there are still some (model-dependent) differences, such as central galaxies being too massive, and galaxy colours (g - r) being bluer (about 0.2 dex lower at the peak position) than in observations. The agreement in gas scaling relations down to 1013 h -1 M· between the simulations indicates that particulars of the sub-grid modelling of the baryonic physics only has a weak influence on these relations.We also include - where appropriate - a comparison to three semi-analytical galaxy formation models as applied to the same underlying dark-matteronly simulation. All simulations and derived data products are publicly available.
Neuropilins: Their transcriptional regulation and role in ischemia-induced neuronal cell death
Creators: name: Sheldrick, Melissa Lynn
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Neuroscience.

description: Elucidation of molecular mechanisms modulating the death and failure of neurons to regenerate after cerebral ischemia is important in developing therapeutics to stroke. Here, results demonstrate that the pro-death transcription factor E2F1 inhibits neuronal survival through up-regulation of the receptor for axon repulsive guidance molecule, NRP-1. First, NRP-1 is shown as a direct target of E2F1 based on: reactivation of NRP-1 expression in E2F1-/- neurons after E2F1 replacement, EMSA and reporter assays confirming E2F1 binding and activation of the NRP-1 promoter, respectively. Second, pharmacological and genetic inhibition of NRP-1 conferred neuroprotection. Collectively, these findings support a model in which E2F1 targets NRP1 to modulate axonal damage and neuronal death in response to cerebral ischemia. Future work should determine the differential contributions of NRP-1 and NRP-2 in neuronal survival. Studies in vivo will also confirm the therapeutic benefit of inhibition of NRPs in stroke recovery.
Globular cluster and galaxy formation: M31, the Milky Way, and implications for globular cluster systems of spiral galaxies
Creators: name: Burstein, David
name: Li, Yong
name: Freeman, Kenneth C.
name: Norris, John E.
name: Bessell, Michael S.
name: Bland-Hawthorn, Joss
name: Gibson, Brad K.
name: Beasley, Mlchael A.
name: Lee, Hyun Chul
name: Barbuy, Beatriz
name: Huchra, John P.
name: Brodif, Jean P.
name: Forbes, Duncan
Publisher: name: Swinburne
Year: 2024

description: We find that the globular cluster (GC) systems of the Milky Way and of our neighboring spiral galaxy, M31, comprise two distinct entities, differing in three respects. First, M31 has a set of young GCs, ranging in age from a few times 102 Myr to 5 Gyr old, as well as old GCs. No such very young GCs are known in the Milky Way. Second, we confirm that the oldest M31 GCs have much higher nitrogen abundances than do Galactic GCs at equivalent metallicities, while carbon abundances appear normal for the GCs in both galaxies. Third, Morrison and coworkers have shown that M31 has a subcomponent of GCs that follow closely the disk rotation curve of that galaxy. Such a GC system in our own Galaxy has yet to be found. The only plausible scenario for the existence of the young M31 GC comes from the hierarchical-clustering-merging (HCM) paradigm for galaxy formation. We infer that M31 has absorbed more of its contingent of dwarf systems in the recent past than has the Milky Way. This inference has three implications: First, all spiral galaxies could differ in their GC properties, depending on how many companions each galaxy has and when the parent galaxy absorbs them. In this spectrum of possibilities, apparently the Milky Way ties down one end, in which almost all of its GCs were absorbed 10-12 Gyr ago. Second, it suggests that young GCs are preferentially formed in the dwarf companions of parent galaxies and then absorbed by the parent galaxy during mergers. Third, the young GCs seen in tidally interacting galaxies might come from the dwarf companions of these galaxies, rather than be made anew in the tidal interaction. However, there is no ready explanation for the marked difference in nitrogen abundance for the stars in the old M31 GCs relative to those in the oldest Galactic GCs, especially the most metal-poor GCs in both galaxies. The predictions made by Li & Burstein regarding the origin of nitrogen abundance in GCs are consistent with what is found for the old M31 GCs compared to that for the two 5 Gyr old M31 GCs.
Introduction
Creators: name: Belladelli, Anna
Publisher: name: Iperstoria
Year: 2014

description: Negli ultimi quattro anni si è assistito a un crescendo di movimenti rivoluzionari e riformisti in tutto il mondo. Dalla Primavera Araba agli 15-M spagnoli (erroneamente definiti indignados), dalla protesta contro l’austerità selvaggia in Grecia a quella anti-Erdogan in Turchia, fino ai recentissimi risvolti drammatici delle manifestazioni pro-europeiste in Ucraina, le popolazioni in rivolta hanno catalizzato i media ufficiali e hanno anche pervaso i nuovi media grazie ai social network e al citizen journalism, che hanno consentito ai manifestanti non soltanto di rendersi più visibili, offrendo la propria versione degli eventi, ma anche di restare in contatto con movimenti affini in giro per il mondo. Ciò ha permesso un fenomeno nuovo e interessante sia dal punto di vista storico-politico e sociale, sia linguistico: si sono verificate migrazioni di slogan, contaminazioni linguistiche e consonanze di istanze e modalità di resistenza mai osservate nei decenni precedenti.
description: Iperstoria, No 3 (2014): Orizzonti di Occupy: il linguaggio di OWS e di altre forme odierne di protesta popolare
Supplementary document for Breaking Planar Symmetries by Single Layered Metasurface for Realizing Unique On-chip Chiroptical Effects - 4921885.pdf
Creators: name: MEHMOOD, MUHAMMAD QASIM
name: Naeem, Taimoor
name: Sarwar, Ahsan
name: Zubair, Muhammad
name: Tauqeer, Tauseef
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplementary Information
title: Was tun bei extremer Hitze?
title: Was tun bei extremer Hitze?
titleType: AlternativeTitle
Creators: name: Schneider, Achim G.
Publisher: name: My University
Year: 2020

description: Richtig heiße Tage werden aufgrund des Klimawandels auch in Deutschland immer häufiger. Warum gerade Ältere besser davor gewarnt werden müssten, wie Frankreich seine Bevölkerung schützt - und was die besten Tipps bei Hitze sind. Quelle: www.apotheken-umschau.de
System-identification of gene regulatory networks by systematic gene perturbation analysis
Creators: name: Abedi, Vida
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Biology, Genetics.

description: Systems biology is an interdisciplinary field that combines engineering and molecular biology to better understand the 'design principles' of biological systems. One of the main goals in systems biology is to understand and map complex biological networks. In order to achieve this goal, tools able to process the non-linearity and high dimensionality of biological systems are urgently needed. To develop, test and benchmark tools for investigation of biological processes, it is important to utilize a model system that is able to provide a glimpse of complexity found in higher organisms, and be simple enough such that detailed studies can be performed rapidly, accurately, and reproducibly. Here, we have developed a system-identification framework for the extraction of quantitative and mechanistic information about causal relationship among genes using the canonical galactose utilization pathway in Saccharomyces cerevisiae. This framework, referred to as s&barbelow;ystematic g&barbelow;ene p&barbelow;erturbation a&barbelow;nalysis (SGPA), is based on the effects of systematic pair-wise gene deletions. In essence, the method establishes dynamical models of the regulatory network from single-cell measurements of steady-state input-output relationships, in systematically perturbed networks. SGPA framework is successful in identifying the network structure for the GAL system. This strategy leads the way to a better application of available resources and provides a scalable framework for system-identification and reverse-engineering of biological networks based on in vivo systematic data generation.
The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers
Creators: name: Zanetti-Domingues, Laura C.
name: Korovesis, Dimitrios
name: Needham, Sarah R.
name: Tynan, Christopher J.
name: Sagawa, Shiori
name: Roberts, Selene K.
name: Kuzmanic, Antonija
name: Ortiz-Zapater, Elena
name: Jain, Purvi
name: Roovers, Rob C.
name: Lajevardipour, Alireza
name: van Bergen en Henegouwen, Paul M. P.
name: Santis, George
name: Clayton, Andrew
name: Clarke, David T.
name: Gervasio, Francesco L.
name: Shan, Yibing
name: Shaw, David E.
name: Rolfe, Daniel J.
name: Parker, Peter J.
name: Martin-Fernandez, Marisa L.
Publisher: name: Swinburne
Year: 2024

description: Our current understanding of epidermal growth factor receptor (EGFR) autoinhibition is based on X-ray structural data of monomer and dimer receptor fragments and does not explain how mutations achieve ligand-independent phosphorylation. Using a repertoire of imaging technologies and simulations we reveal an extracellular head-to-head interaction through which ligand-free receptor polymer chains of various lengths assemble. The architecture of the head-to-head interaction prevents kinase-mediated dimerisation. The latter, afforded by mutation or intracellular treatments, splits the autoinhibited head-to-head polymers to form stalk-to-stalk flexible non-extended dimers structurally coupled across the plasma membrane to active asymmetric tyrosine kinase dimers, and extended dimers coupled to inactive symmetric kinase dimers. Contrary to the previously proposed main autoinhibitory function of the inactive symmetric kinase dimer, our data suggest that only dysregulated species bear populations of symmetric and asymmetric kinase dimers that coexist in equilibrium at the plasma membrane under the modulation of the C-terminal domain.
Indikatoren für die ökonomische Bedeutung von Wasser und Gewässern
Creators: name: Geyler, Stefan
name: Laforet, Lydie
name: Rüger, Jana
Publisher: name: My University
Year: 2018
Subjects: subject: Produzentenrente
subject: Konsumentenrente
subject: Opportunitätskosten
subject: Preisentwicklung
subject: Beschäftigungseffekt
subject: Nachhaltigkeit
subject: Binnenschifffahrt
subject: Kühlwasser
subject: Bewässerung
subject: Benchmarking
subject: Gewässernutzung
subject: ökonomischer Wert
subject: Nutzenstiftung
subject: öffentliche Trinkwassernutzung
subject: VGR
subject: UGR
subject: PSR-Ansatz
subject: Wasser

description: In der Studie werden Ansätze vorgestellt, die eine Abschätzung des ökonomischen Wertes von Wasser und Gewässern erlauben. Als Bewertungskonzept wurde mit einer „Landkarte der Bewertung“ ein mehrdimensionaler Bewertungsansatz entwickelt, welcher die wirtschaftliche Inanspruchnahme von Wasser abbildet. Der Bewertungsansatz wurde beispielhaft für vier ausgewählte Wassernutzungen angewendet: 1.    Für die Binnenschifffahrt zur Güterbeförderung, 2.    die öffentliche Wasserversorgung / Abwasserbeseitigung von Haushalten,3.    die Kühlung zur thermoelektrischen Stromproduktion sowie 4.    die Bewässerung in der Landwirtschaft. Für diese Wassernutzungen wurden die Bewertungsansätze in Bezug auf Deutschland, Nordrhein-Westfalen sowie Sachsen ausgewertet.
Novel bioconjugation methods for protein microarrays and cell surface labelling
Creators: name: Hoop, Kelly Anne
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Chemistry, Biochemistry.

description: Chemical tools play an important role in research across many fields in science. The development of new tools for use in biology is therefore of the utmost importance. This thesis will discuss the development of two new chemically based tools for the field of biology. In the first part, the development of a new bioconjugation reaction will be discussed. The benzoin condensation was explored as a possible new bioconjugation reaction for the functionalization of surfaces with biomolecules. Using thiamine and other N-heterocyclic carbenes, it was shown that aromatic aldehydes can be tethered to a Si surface bearing a second aromatic aldehyde in aqueous media. In the second part, development of a new imaging technique will be discussed. Surface enhanced Raman scattering was successfully employed to image multiple targets on the surface of a cell. The design and synthesis of various Raman active ligand functionalized Ag nanoparticles allowed for the simultaneous imaging of two membrane proteins present in cardiomyocyte cells.
Primary care practice in Ontario: An analysis of the factors that affect physician supply and activity
Creators: name: Donnelly, James G
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Business Administration, Management.
subject: Health Sciences, Health Care Management.

description: Health care reform is an essential and continuous process as a nation's medical system adjusts to meet changing needs in the population. It has been recognized that the Canadian health care system is in need of revolutionary change. Many other countries have had similar experiences to Canada in both resource shortages and reform process. The population of Ontario is growing and becoming older. Older persons place greater demands on the health care system. At the same time the Ontario physician workforce has decreased in size, increased in age and has more female entrants. Elderly physicians reduce their workloads as they reach the age of 65 years. Female physicians take on lower workloads than male physicians, especially in the early part of their careers. Over the past eight years there have been less entrants to Family Practice and more to specialty services. As well, in the past five years nearly 60 percent of Family Practice physicians have reduced their scope of care by limiting their practices. Taken together these observations demonstrate that while there is an increased need for primary and secondary care physicians there has also been a concurrent reduction of the number of physicians both in terms of census and also in terms of workload. In the past decade the Universities of Ontario have increased tuition fees significantly with respect to the other provinces. Financial pressures and control of hours (lifestyle control) may further limit the intake of post-graduate Family Practice physicians. Reversing these trends will require increasing the physician workforce and the development of programs to encourage entry into primary care.
Extraction and analysis of antioxidant capacity in rice bran extracts from different Sarawak local rice varieties
Creators: name: Xian Wen, Tan
Publisher: name: Swinburne
Year: 2024

description: Sarawak is blessed with many different local rice varieties. However, the nutritional contents and value-added processing possibilities of these local rice varieties remain underexplored. This research project was conducted to extract and assess natural antioxidant contents from rice bran of selected Sarawak local rice varieties. The rice bran extracts (RBE) were then further tested with in vitro chemical- and cell-based antioxidant assays preliminarily to evaluate their respective antioxidant capacities in alleviating oxidative injuries. The results revealed that RBE of different Sarawak local rice varieties contain significant amount of natural antioxidants. According to the current finding, Bajong LN RBE has the highest contents of phenolic compounds, flavonoids, and γ-oryzanol among all the tested samples. It was also discovered that higher average total phenolic, flavonoids, and tocotrienols contents were detected in RBE of Sarawak local rice varieties studied as compared to those in certain rice varieties cultivated elsewhere. In vitro chemical-based antioxidant assays further revealed the dose-dependent 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging capabilities of RBE to which the effectiveness differed among RBE of different local rice varieties. Among all the tested rice varieties, highest free-radical scavenging activity was detected with Bajong LN RBE and was significantly higher than that with RBE of commercial rice variety, MR219. Both Bajong LN and MR219 RBE were selected for in vitro cell-based antioxidant assay. Here, the H9c2(2-1) cardiomyocyte was used and the cellular induction effects with selected RBE and H2O2 were studied. Incubation of H9c2(2-1) with RBE and H2O2 showed dose-dependent cytotoxic effects respectively. Such observation revealed the potential prooxidant activity of RBE which consequently reduced cell viability at higher concentration. Cellular induction with safe dose range of RBE showed significant improvement in enzymatic activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) in H9c2(2-1). Co-incubation of H9c2(2-1) with RBE and H2O2 further revealed the potential of RBE in alleviating H2O2-induced oxidative injuries as observed through a right shift in IC50 of H2O2. Higher increment in IC50 of H2O2 was detected with Bajong LN RBE as compared to MR219 RBE. Besides that, significant up-regulations in enzymatic activity and
expression of CAT were also reported from H9c2(2-1) co-incubated with RBE and H2O2. As a summary, the present result put forward the potential of RBE as a source of antioxidants for alleviation of oxidative injuries in cardiovascular diseases (CVD). Additional studies are still required to further investigate the utilization of RBE as a strategy to combat oxidative stress-induced CVD.
North American and Greenland modern pollen data for multi-scale paleoecological and paleoclimatic applications
Creators: name: Whitmore, Johanne
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Geography.
subject: Paleoecology.

description: The status of the modern pollen network in North America and Greenland is presented by assembling a database for use in quantitative calibration studies and paleoenvironmental reconstructions. The geo-referenced database includes 4569 samples from all regions of the continent. The database includes 934 pollen taxa that range from common taxa to those that may be used for regional-scale reconstructions. Climate data and vegetation characteristics are assigned to every site. A series of procedures, both automated and manual, were used to check the qualify of the pollen data. Data are currently available for almost all of North America, with variable density. The squared-chord distance computed between samples shows that most modern pollen samples find analogues in the same vegetation zone and the temperature and precipitation computed from the best analogue are highly correlated with actual value at the site. Analysis of the contemporary distribution of pollen taxa in relation to their vegetation range illustrates factors that must be considered when using these data as well as the potential for more detailed analysis of understudied taxa.
A decentralized redundant peer-to-peer system based on Chord: Routing, scalability, robustness
Creators: name: Xie, Ming
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Computer Science.

description: Peer-to-peer systems can share the computing resources and services by directly communicating within a widely distributed network. Our research focuses on locating, routing, scalability and robustness in the decentralized redundant P2P system. Chord[1] is an efficient peer-to-peer lookup protocol for its simplicity, provable correctness and performance. It can locate a key through a sequence of O(log n) other nodes toward the destination, where n is the total number of nodes. In this thesis, we present three enhanced models based on Chord to improve the routing performance and data availability. The k-Chord model helps lookup to approach the destination rapidly within the first several hops. The successor routing model applies the successor list as a part of the routing table to locate the destination accurately by merging the last several hops into one hop if the current lookup location is located within the range of the successors. The hybrid model is a combination of the former two models, and nearly halves the routing path length of Chord system. We also discuss the scalability and fault tolerance of the three models.
Air Quality 2018
Creators: name: Dauert, Ute
name: Feigenspan, Stefan
name: Kessinger, Susan
name: Minkos, Andrea
Publisher: name: My University
Year: 2019
Subjects: subject: Luftgüte
subject: PM10
subject: PM2,5
subject: Stickstoffdioxid
subject: Ozon
subject: air quaility
subject: PM2.5
subject: nitrogen dioxide
subject: ozone
subject: Air

description: This evaluation of air quality in Germany in the year 2018 is based on preliminary data which has not yet been conclusively audited from the air monitoring networks of the federal states and the UBA, valid on 18rd January 2019. Due to the comprehensive quality assurance within the monitoring networks, the final data will only be available in mid-2019. The currently available data allows for a general assessment of the past year. The following pollutants were subject to consideration: particulate matter (PM10 and PM2.5), nitrogen dioxide (NO2) and ozone (O3), since, the limit and target values for the protection of human health are still exceeded for such substances. Quelle: Verlagsinformation
description: This evaluation of air quality in Germany in the year 2018 is based on preliminary data which has not yet been conclusively audited from the air monitoring networks of the federal states and the ⁠UBA⁠, valid on 18rd January 2019. Due to the comprehensive quality assurance within the monitoring networks, the final data will only be available in mid-2019. The currently available data allows for a general assessment of the past year. The following pollutants were subject to consideration: particulate matter (⁠PM10⁠ and PM2.5), nitrogen dioxide (NO2) and ozone (O3), since, the limit and target values for the protection of human health are still exceeded for such substances.
title: Afectación mamaria por procesos linfoproliferativos.
Creators: name: Escribano Talaya, Margarita
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Lymphoma
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Mammography
subject: Breast

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar los hallazgos radiológicos de la afectación mamaria por procesos linfoproliferativos y valorar el contexto clínico,
las características anatomo-patológicas y los aspectos pronósticos y...
Waste the waist: A pilot randomised controlled trial of a primary care based intervention to support lifestyle change in people with high cardiovascular risk
Creators: name: Greaves, Colin
name: Gillison, Fiona
name: Stathi, Afroditi
name: Bennett, Paul
name: Reddy, Prasuna
name: Dunbar, James
name: Perry, Rachel
name: Messom, Daniel
name: Chandler, Roger
name: Francis, Margaret
name: Davis, Mark
name: Green, Colin
name: Evans, Philip
name: Taylor, Gordon
Publisher: name: Swinburne
Year: 2024

description: Background: In the UK, thousands of people with high cardiovascular risk are being identified by a national risk-assessment programme (NHS Health Checks). Waste the Waist is an evidence-informed, theory-driven (modified Health Action Process Approach), group-based intervention designed to promote healthy eating and physical activity for people with high cardiovascular risk. This pilot randomised controlled trial aimed to assess the feasibility of delivering the Waste the Waist intervention in UK primary care and of conducting a full-scale randomised controlled trial. We also conducted exploratory analyses of changes in weight. Methods: Patients aged 40-74 with a Body Mass Index of 28 or more and high cardiovascular risk were identified from risk-assessment data or from practice database searches. Participants were randomised, using an online computerised randomisation algorithm, to receive usual care and standardised information on cardiovascular risk and lifestyle (Controls) or nine sessions of the Waste the Waist programme (Intervention). Group allocation was concealed until the point of randomisation. Thereafter, the statistician, but not participants or data collectors were blinded to group allocation. Weight, physical activity (accelerometry) and cardiovascular risk markers (blood tests) were measured at 0, 4 and 12 months. Results: 108 participants (22% of those approached) were recruited (55 intervention, 53 controls) from 6 practices and 89% provided data at both 4 and 12 months. Participants had a mean age of 65 and 70% were male. Intervention participants attended 72% of group sessions. Based on last observations carried forward, the intervention group did not lose significantly more weight than controls at 12 months, although the difference was significant when co-interventions and co-morbidities that could affect weight were taken into account (Mean Diff 2.6Kg. 95%CI: -4.8 to -0.3, p = 0.025). No significant differences were found in physical activity. Conclusions: The Waste the Waist intervention is deliverable in UK primary care, has acceptable recruitment and retention rates and produces promising preliminary weight loss results. Subject to refinement of the physical activity component, it is now ready for evaluation in a full-scale trial.
Gut Mucosal Proteins and Bacteriome Are Shaped by the Saturation Index of Dietary Lipids
Creators: name: Abulizi, Nijiati
name: Quin, Candice
name: Brown, Kirsty
name: Chan, Yee Kwan
name: Gill, Sandeep K.
name: Gibson, Deanna L.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The dynamics of the tripartite relationship between the host, gut bacteria and diet in the gut is relatively unknown. An imbalance between harmful and protective gut bacteria, termed dysbiosis, has been linked to many diseases and has most often been attributed to high-fat dietary intake. However, we recently clarified that the type of fat, not calories, were important in the development of murine colitis. To further understand the host-microbe dynamic in response to dietary lipids, we fed mice isocaloric high-fat diets containing either milk fat, corn oil or olive oil and performed 16S rRNA gene sequencing of the colon microbiome and mass spectrometry-based relative quantification of the colonic metaproteome. The corn oil diet, rich in omega-6 polyunsaturated fatty acids, increased the potential for pathobiont survival and invasion in an inflamed, oxidized and damaged gut while saturated fatty acids promoted compensatory inflammatory responses involved in tissue healing. We conclude that various lipids uniquely alter the host-microbe interaction in the gut. While high-fat consumption has a distinct impact on the gut microbiota, the type of fatty acids alters the relative microbial abundances and predicted functions. These results support that the type of fat are key to understanding the biological effects of high-fat diets on gut health.
title: Revisión de la ataxia mediante Resonancia Magnética
Creators: name: Ontañon Garcés, Jose Mª
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: MR
subject: Education
subject: Pathology

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Retrospectivamente revisamos informes de RM de pacientes con ataxia realizados en cinco centros diferentes entre 1990 y mediados de 2011. Todas las RM fueron realizadas en equipos de 1 o 1,5 T (Siemens o Phillips).
Los protocolos consistieron en...
Mechanisms governing the growth of self-assembled quantum dots.
Creators: name: Riel, Bruno J.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Physics, Condensed Matter.

description: We produced self-assembled quantum dot (QD) samples of InAs on GaAs by molecular beam epitaxy (MBE). With these, we explored growth effects as a function of InAs coverage for three arsenic pressures, and as a function of arsenic pressure at a specific InAs coverage. During growth, the samples were studied using reflection high energy electron diffraction (RHEED). These RHEED measurements were compared to low energy electron diffraction (LEED) measurements. To perform this ex-situ LEED characterisation, some samples were covered with an amorphous arsenic cap. This cap was thermally evaporated producing a clean, non-oxidised surface that was studied using LEED. We obtained non-ambiguous identification of the GaAs (001) surface reconstructions as well as timing information for the 2D to 3D transition during the growth of InAs on GaAs. Post growth characterisation of two sets of self-assembled QD samples, twelve samples in all, revealed the following: As a function of increasing the arsenic pressure used in QD growth, the photoluminescence (PL) of capped QDs is first redshifted at low arsenic pressures, and then blueshifted at high arsenic pressures. Scanning electron microscopy and atomic force microscopy of uncapped QDs show that as the arsenic pressure increases, the QD density increases while the average QD width and height decrease monotonically; these trends are consistent with the shift in PL for the high arsenic pressure samples, but are inconsistent with the shift in PL for the low pressure samples. This leads us to proposing a mechanism by which QDs may be modified as they are overgrown with capping material. We discuss the effects of adjusting the arsenic pressure on the formation of QDs and the mechanism by which QDs may be modified during capping.
Two fatal and four surviving cases after accidental infusion of ropivacaine
Creators: name: Winkler, Michaela
name: Alt, Andreas
name: Dietzsch, Susann
name: Kunz, Sebastian N.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: 3-OH-ropivacaine
subject: GC–MS
subject: Analgesic
subject: Fatal poisoning
subject: DDC 610 / Medicine & health
subject: Ropivacaine
subject: Analgesics
subject: Malpractice
subject: Ropivacain
subject: Analgetikum
subject: Medizinschaden

description: Purpose In this paper, we describe six cases, where patients were falsely treated with pre-filled ropivacaine solution instead of medical saline solution for postoperative settings. Two of the patients died because of fatal concentrations of ropivacaine in blood, four survived with no further physical injury, and two of them showed typical intoxication symptoms. The collected blood and urine samples of the deceased, as well as the surviving patients, were analyzed in laboratory routine screening. Methods Ropivacaine and its main metabolite 3-OH-ropivacaine were analyzed by gas chromatography–mass spectrometry. Results All of the six cases showed positive blood results of ropivacaine. Due to the poorly secured sample material of the survived patients at hospital, the quantitative examination of 3-OH-ropivacaine could not be carried out. In one fatal case, there were ropivacaine and 3-OH-ropivacaine traceable in urine. In all cases, metamizole was found in blood and traces of piritramide in urine. The amount of metamizole was within the upper limits of therapeutical treatment values. Patients with lower blood concentrations of ropivacaine showed more physical symptoms as compared to those with higher concentrations of active substances. Conclusions In the context of symptom development and intoxication, the speed of injection was a very important factor to cause fatal ropivacaine cases. To our knowledge, these are the first reported cases of fatal intoxication with ropivacaine.
title: Variantes vasculares de interés en angioTC/RM de arterias cervicales e intracraneales.
Creators: name: Salame Gamarra, Fares
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: CT-Angiography
subject: MR-Angiography
subject: Neuroradiology brain
subject: Head and neck
subject: Anatomy

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
La evaluación de las arterias cervicales y cerebrales es habitual,
sobre todo como parte del estudio etiológico de la patología isquémica cerebral. Revisamos las variantes vasculares más significativasbien porque plantean DD con patologías...
Cloning and expression of the glycoproteins of pichinde virus by vaccinia virus.
Creators: name: Wanas, Essam A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Biology, Microbiology.

description: Pichinde virus (Pic), like the other arenaviruses, possesses two glycoproteins, GP1 and GP2, that are derived by proteolytic cleavage from a precursor molecule, GPC. Within the arenaviruses, GP1 is the most heterogeneous protein, and GP1 of Pic differs from that of the other arenaviruses in having twice as many potential N-linked glycosylation sites, most of which appear to be utilized. In order to examine the effects of this heavy glycosylation on Pic GP1 structure and inmunogenicity, GPC of Pic was cloned and expressed in vaccinia virus. The recombinant vaccinia (vvGPC) expresses authentic Pic GPC as demonstrated by immunoprecipitation with MAb and several polyclonal anti-Pic sera. GPC expressed in vaccinia is fully glycosylated as it comigrates with Pic GPC. At the same time, sequence analysis of cDNA shows both nucleotide and amino acid changes compared to published sequences for Pic GPC, indicating that variation in the same strain of this virus occurs as virus is passaged in separate laboratories. Experiments to assess the ability of Pic GPC expressed in vaccinia to elicit anti-Pic antibody show that rabbit anti-vvGPC detects authentic Pic GPC and GP1. Site-directed mutagenesis was employed to remove a potential N-linked glycosylation site (aa 181-183) in Pic GPC. Attempts were made to produce recombinant vaccinia, vvGPC-183, harbouring the mutant Pic GPC.
Multimodal in vivo staging in amyotrophic lateral sclerosis using artificial intelligence
Creators: name: Behler, Anna
name: Müller, Hans-Peter
name: Del Tredici, Kelly
name: Braak, Heiko
name: Ludolph, Albert C.
name: Lulé, Dorothée
name: Kassubek, Jan Rainer
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: FIBER TRACKING
subject: DYSFUNCTION
subject: TDP-43
subject: MULTICENTER
subject: PATTERNS
subject: BULBAR
subject: SCREEN
subject: DDC 610 / Medicine & health
subject: Amyotrophic lateral sclerosis
subject: Neuropathology
subject: Diffusion tensor imaging
subject: Fiber optic technology; Methods
subject: Cluster analysis
subject: Myatrophische Lateralsklerose
subject: Neuropathologie
subject: Diffusionsgewichtete Magnetresonanztomografie
subject: Cluster-Analyse

description: Background The underlying neuropathological process of amyotrophic lateral sclerosis (ALS) can be classified in a four-stage sequential pTDP-43 cerebral propagation scheme. Using diffusion tensor imaging (DTI), in vivo imaging of these stages has already been shown to be feasible for the specific corticoefferent tract systems. Because both cognitive and oculomotor dysfunctions are associated with microstructural changes at the brain level in ALS, a cognitive and an oculomotor staging classification were developed, respectively. The association of these different in vivo staging schemes has not been attempted to date. Methods A total of 245 patients with ALS underwent DTI, video-oculography, and cognitive testing using Edinburgh Cognitive and Behavioral ALS Screen (ECAS). A set of tract-related diffusion metrics, cognitive, and oculomotor parameters was selected for further analysis. Hierarchical and k-means clustering algorithms were used to obtain an optimal cluster solution. Results According to cluster analysis, differentiation of patients with ALS into four clusters resulted: Cluster A showed the highest fractional anisotropy (FA) values and thereby the best performances in executive oculomotor tasks and cognitive tests, whereas cluster D showed the lowest FA values, the lowest ECAS scores, and the worst executive oculomotor performance across all clusters. Clusters B and C showed intermediate results regarding parameter values. Discussion In a multimodal dataset of technical assessments of brain structure and function in ALS, an artificial intelligence-based cluster analysis showed high congruence of DTI, executive oculomotor function, and neuropsychological performance for mapping in vivo correlates of neuropathological spreading.
Emerging Point-of-care Technologies for Food Safety Analysis
Creators: name: Choi, Jane Ru
name: Yong, Kar Wey
name: Choi, Jean Yu
name: Cowie, Alistair C.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Food safety issues have recently attracted public concern. The deleterious effects of compromised food safety on health have rendered food safety analysis an approach of paramount importance. While conventional techniques such as high-performance liquid chromatography and mass spectrometry have traditionally been utilized for the detection of food contaminants, they are relatively expensive, time-consuming and labor intensive, impeding their use for point-of-care (POC) applications. In addition, accessibility of these tests is limited in developing countries where food-related illnesses are prevalent. There is, therefore, an urgent need to develop simple and robust diagnostic POC devices. POC devices, including paper- and chip-based devices, are typically rapid, cost-effective and user-friendly, offering a tremendous potential for rapid food safety analysis at POC settings. Herein, we discuss the most recent advances in the development of emerging POC devices for food safety analysis. We first provide an overview of common food safety issues and the existing techniques for detecting food contaminants such as foodborne pathogens, chemicals, allergens, and toxins. The importance of rapid food safety analysis along with the beneficial use of miniaturized POC devices are subsequently reviewed. Finally, the existing challenges and future perspectives of developing the miniaturized POC devices for food safety monitoring are briefly discussed.
title: Biopsia del ganglio centinela: Visión del radiólogo general.
Creators: name: LOMEÑA ALVAREZ, GUILLERMO
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Biopsy
subject: Ultrasound
subject: Breast

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
- Puesta al día en la selección de pacientes,
indicaciones y contraindicaciones de la biopsia de ganglio centinela (BGC). - Mostrar resultados de BGC en nuestro...