cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Performance of Type III stilling basins for stepped spillways
Creators: name: Frizell, K. W.
name: Svoboda, C.
name: Matos, J.
name: Colorado State University. Department Of Engineering, Publisher
Publisher: name: Mountain Scholar
Year: 2016
Subjects: energy dissipation
stepped spillways
stilling basin
Froude number

description: Presented at the Protections 2016: 2nd international seminar on dam protection against overtopping: concrete dams, embankment dams, levees, tailings dams held on 7th-9th September, 2016, at Colorado State University in Fort Collins, Colorado, USA. The increasing demand for dam and levee safety and flood protection has motivated new research and advancements and a greater need for cost-effective measures in overtopping protection as a solution for overtopping concerns at levees and dams. This seminar will bring together leading experts from practice, research, development, and implementation for two days of knowledge exchange followed by a technical tour of the Colorado State University Hydraulic Laboratory with overtopping flume and wave simulator. This seminar will focus on: Critical issues related to levees and dams; New developments and advanced tools; Overtopping protection systems; System design and performance; Applications and innovative solutions; Case histories of overtopping events; Physical modeling techniques and recent studies; and Numerical modeling methods.
description: Includes bibliographical references.
description: Energy dissipation within hydraulic structures continues to be one of the major issues facing the designer of new or rehabilitated facilities, such as for overtopping protection of embankment dams. The energy dissipation characteristics of stepped spillways have been well documented, both for low- and high-head dams. Interestingly, much of the generalized research on stepped channels and spillways over the past few decades, while concerned with the amount of energy dissipated on the steps themselves, has contributed very little to generalized design criteria for terminal dissipation structures/stilling basins. Many site specific studies have included work on modifications to stilling basins to account for the increased energy dissipation on the steps, typically resulting in a shortening of the basin length. Others have included some stilling basin parameters within their studies. A few studies have attempted to provide generalized design guidance for the use of specific types of stilling basins with stepped chutes and spillways. This paper will focus on recent studies at the Reclamation laboratory that evaluated the application of smooth channel design criteria for Type III stilling basins to a variety of stepped spillway slopes. While there is a lack of specific generalized studies for stilling basin performance over the range of all types of stepped spillways that exist, there appears to be adequate data available to allow the designer to select and size an appropriate stilling basin for most types of stepped spillways currently in use, including RCC overtopping protection systems.
Axial Sensory Tricks in Chorea–Acanthocytosis: Insights into Phenomenology
Creators: name: Bhidayasiri, Roongroj
name: Jitkritsadakul, Onanong
name: Walker, Ruth H.
Publisher: name: Columbia University
Year: 2017
Subjects: Phenomenology
Neurology
Chorea
Kinesiology
Movement disorders

description: Background: Trunk flexion and axial extension are characteristic symptoms of chorea–acanthocytosis (ChAc).

Phenomenology Shown: A 41-year-old male with ChAc (confirmed by VPS13A mutations) reported that his involuntary axial movements were significantly ameliorated by either folding his arms over his chest or putting his hands behind his head.

Educational Value: These apparent “sensory tricks” suggest a dystonic pathophysiology, and also merit further study to analyze their potential for symptom control in ChAc.
Remarks on the Rayleigh-Benard Convection on Spherical Shells
Creators: name: Wang, Shouhong
name: Yang, Ping
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences
subject: 35, 76, 86

description: The main objective of this article is to study the effect of spherical geometry on dynamic transitions and pattern formation for the Rayleigh-Benard convection. The study is mainly motivated by the importance of spherical geometry and convection in geophysical flows. It is shown in particular that the system always undergoes a continuous (Type-I) transition to a $2l_c$-dimensional sphere $S^{2lc}$, where lc is the critical wave length corresponding to the critical Rayleigh number. Furthermore, it has shown in [12] that it is critical to add nonisotropic turbulent friction terms in the momentum equation to capture the large-scale atmospheric and oceanic circulation patterns. We show in particular that the system with turbulent friction terms added undergoes the same type of dynamic transition, and obtain an explicit formula linking the critical wave number (pattern selection), the aspect ratio, and the ratio between the horizontal and vertical turbulent friction coefficients.
title: An Earthquake Catalogue for Bulgaria and Adjacent Areas since 1981
Creators: name: Solakov, Dimcho
name: Simeonova, Stela
name: Raykova, Plamena
name: Aleksandrova, Irena
Publisher: name: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 432-442
Year: 2020
Subjects: subject: FOS: Earth and related environmental sciences

description: A homogeneous earthquake catalogue for Bulgaria and adjacent areas covering the period 1981–2019 is presented. The existing catalogues (including instrumental seismicity) for Bulgaria, covering the time period 1981–2000, were updated for the time period 2001-2019 using instrumentally determined focal earthquake parameters. In the present update catalogue, MW is calculated for the entire period 1981–2019 applying the regression equations converting magnitude scales used in Bulgarian seismological routine practice (Md and MP ) to the most reliable and widely used scale of magnitude, i.e. the seismic moment magnitude, MW. Thus, a magnitude homogeneous catalogue concerning MW scales is presented. The extended catalogue contains 645 independent events. The completeness test revealed that the catalogue is complete for moment magnitudes larger than or equal to 3.2 for the last 39 yr.
description: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 432-442
Portal de Periódicos Udesc no YouTube: compartilhar conhecimento vale a pena!
Creators: name: Souza, Marcela Reinhardt de
Publisher: name: figshare
Year: 2021
Subjects: subject: 80706 Librarianship
subject: FOS: Media and communications

description: Apresenta o trabalho realizado na Biblioteca Universitária da UDESC com o desenvolvimento da playlist para capacitação de pessoas no contexto de editoração científica.
Overflow for the complete failure of the downstream shell of a rockfill dam
Creators: name: Alves, R. M.
name: Toledo, M. Á.
name: Morán, R.
name: Colorado State University. Department Of Engineering, Publisher
Publisher: name: Mountain Scholar
Year: 2016
Subjects: overtopping
rockfill dam
failure flow
dam protection

description: Presented at the Protections 2016: 2nd international seminar on dam protection against overtopping: concrete dams, embankment dams, levees, tailings dams held on 7th-9th September, 2016, at Colorado State University in Fort Collins, Colorado, USA. The increasing demand for dam and levee safety and flood protection has motivated new research and advancements and a greater need for cost-effective measures in overtopping protection as a solution for overtopping concerns at levees and dams. This seminar will bring together leading experts from practice, research, development, and implementation for two days of knowledge exchange followed by a technical tour of the Colorado State University Hydraulic Laboratory with overtopping flume and wave simulator. This seminar will focus on: Critical issues related to levees and dams; New developments and advanced tools; Overtopping protection systems; System design and performance; Applications and innovative solutions; Case histories of overtopping events; Physical modeling techniques and recent studies; and Numerical modeling methods.
description: Includes bibliographical references.
description: This paper presents the results of experimental research using physical models regarding the failure of the downstream shoulder of rockfill dams caused by overtopping. The aim of this investigation is to analyze how different parameters such as the rockfill permeability, the main geometric dimensions of the dam, or the impervious element type affect the flow that initiates failure and also the ultimate flow needed to break the downstream shell of the dam. The primary objective of this study is to develop predictive models for both discharge flows. For this purpose, tests with stepwise flow increments were performed by varying the rockfill size, the height and width of the dam, the downstream slope and the type of impervious element. The regression analysis was based on results from 61 experimental tests: 50 tests were used to calibrate the formulas and 11 were used for validation. The analysis shows that, for a given dam height, the failure and the initiation discharges depend essentially on the rockfill permeability and, to a lesser extent, on the slope of the downstream shell. The type of impervious element, central core, upstream face or the absence of this element, seems to have no significant effect.
Local mapping of dissipative vortex motion
Creators: name: Raes, B.
name: Van de Vondel, J.
name: Silhanek, A. V.
name: Silva, C. de Souza
name: Gutierrez, J.
name: Kramer, R. B. G.
name: Moshchalkov, V. V.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We explore, with unprecedented single vortex resolution, the dissipation and motion of vortices in a superconducting ribbon under the influence of an external alternating magnetic field. This is achieved by combing the phase sensitive character of ac-susceptibility, allowing to distinguish between the inductive-and dissipative response, with the local power of scanning Hall probe microscopy. Whereas the induced reversible screening currents contribute only inductively, the vortices do leave a fingerprint in the out-of-phase component. The observed large phase-lag demonstrates the dissipation of vortices at timescales comparable to the period of the driving force (i.e. 13 ms). These results indicate the presence of slow microscopic loss mechanisms mediated by thermally activated hopping transport of vortices between metastable states.
description: 5 pages, 2 figures
RDA TIGER D4.1 – Description of Output Support Services and Maintenance Platform
Creators: name: Hugo, Wim
name: Saldner, Simon
Publisher: name: Zenodo
Year: 2023
Subjects: open science
EOSC
RDA

description: Research Data Alliance’s (RDA) Working Groups (WGs) aim to solve a specific research data related issue in a relatively short period of time. In practice, these groups are created by the RDA community, and rely on the voluntary contributions from the community to achieve its stated objectives. While this approach has been demonstrated to be successful in the last decade, certain areas have been identified where improvements can be made. The RDA TIGER project addresses some of these improvements [1]. RDA TIGER establishes a suite of concrete services to support the Working Groups (WG) of the Research Data Alliance (RDA). Work Package 4 in the TIGER project oversees the service for WG Output Support, particularly the RDA Maintenance Platform (RDA-MP), and various output guidance services. The objectives are to ensure high quality, usefulness, maintenance and sustainability of the WG outputs. This report provides a work plan for the activities, outputs and, and services envisaged for the work package.
Do Bradykinesia and Tremor Interfere in Voluntary Movement of Essential Tremor Patients? Preliminary Findings
Creators: name: Goubault, Etienne
name: Nguyen, Hung P.
name: Ayachi, Fouaz S.
name: Bogard, Sarah
name: Duval, Christian
Publisher: name: Columbia University
Year: 2017
Subjects: Tremor
Movement disorders
Motor ability
Neurology

description: Background: The aim of this study was to determine whether tremor and bradykinesia impacted a dexterous activity performed by patients with essential tremor (ET).

Methods: Core bradykinesia was assessed in 27 controls and 15 patients with ET using a rapid alternating movement (RAM) task. Then, participants performed a “counting money” counting tasks while equipped with inertial measurement units to detect and quantify tremor during movement. The time required to perform subsections of the tasks and the rate of failure (errors) were compared between groups using Mann–Whitney U tests and a chi-square test, respectively.

Results: Patients with ET presented with significant bradykinesia during the RAM task and had more tremor during the counting money task. However, the time required to perform the task and rate of failure were similar between groups.

Discussion: Results show that even though bradykinesia was detected during fast movements, and that tremor was present during a task requiring dexterity, both symptoms did not interfere with the performance of patients with ET. This pilot study suggests that there may be a threshold at which tremor will become problematic. Determining this threshold for a wide range of daily activities may help determine when it is appropriate to initiate treatment for patients with ET.
title: The development and evaluation of the cardiovascular assessment screening program
Creators: name: Bruneau, Jill E. E.
Publisher: name: Memorial University of Newfoundland
Year: 2020

description: BACKGROUND: An exploratory mixed methods study, with the philosophical basis of pragmatism and interpretive description, was used to develop, implement, and evaluate an intervention called the Cardiovascular Assessment Screening Program (CASP) to address the underutilization of clinical practice guidelines for cardiovascular screening. The Knowledge-to-Action (KTA) Framework with guideline adaptation was used to guide the study.
 METHODS: In phase 1, the qualitative study, ten interviews and five focus groups were conducted with healthcare providers (HCPs), managers, and the public to gain different perspectives to inform the development of CASP. In phase 2, the quantitative study, CASP was tested in a randomized controlled trial (RCT) with eight nurse practitioners (NPs) and 167 patients aged 40-74 years without previously diagnosed cardiovascular disease (CVD). The intervention group implemented CASP while the control group provided usual care. Phase 3 integration examined the results from phases 1 and 2.
 RESULTS: From the focus groups and interviews conducted in the qualitative phase, themes emerged related to the barriers to, facilitators of, and strategies for CVD screening in the local context. The Theoretical Domains Framework (TDF) was applied to the themes to identify relevant behaviour change techniques and modes of delivery, from which specific intervention components for CASP were developed. Findings from Phase 2, the RCT, showed a statistically and clinically significant difference between the NP intervention group compared to the control group in terms of comprehensiveness of screening, RR = 43.9, 95% CI [13.4, 144.2], p < .0001. The NPs in the intervention group were able to identify multiple risk factors; determine their patients’ level of CVD risk; identify NPs’ and patients’ priorities for action; and encourage individualized goal-setting with patients for heart health. In Phase 3, the integration of results from phases 1 and 2 confirmed and refined strategies for knowledge translation. The mixed methods study results are reported in Manuscript 1, while Manuscript 2 focuses primarily on Phase 2, the results from the RCT. Manuscript 3 discusses strategies to address recruitment issues of HCPs such as nurses and NPs, as participants in research studies.
 CONCLUSION: CASP was effective and can be used by HCPs and patients for CVD screening and management utilizing current guidelines to identify risk factors and promote relevant actions to reduce CVD risk and promote healthy aging.
Polarization rotation, reference frames and Mach's principle
Creators: name: Brodutch, Aharon
name: Terno, Daniel R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Polarization of light rotates in a gravitational field. The accrued phase is operationally meaningful only with respect to a local polarization basis. In stationary space-times, we construct local reference frames that allow us to isolate the Machian gravimagnetic effect from the geodetic (mass) contribution to the rotation. The Machian effect is supplemented by the geometric term that arises from the choice of standard polarizations. The phase accrued along a close trajectory is gauge-independent and is zero in the Schwarzschild space-time. The geometric term may give a dominant contribution to the phase. We calculate polarization rotation for several trajectories and find it to be more significant than is usually believed, pointing to its possible role as a future gravity probe.
description: 4 pages. Final version
Parkinsonism and Tremor in a Patient with Plasmodium vivax Malaria
Creators: name: Park, Jung E.
Publisher: name: Columbia University
Year: 2017
Subjects: Plasmodium vivax
Parkinson's disease--Patients
Movement disorders--Patients
Malaria
Tremor

description: Background: A 57-year-old male diagnosed with Plasmodium vivax malaria presented with a subacute onset of hand tremor, slowness, and gait difficulty.

Phenomenology: A bilateral upper extremity kinetic tremor was seen, as well as a right upper extremity rigidity and body bradykinesia.

Educational Value: Parkinsonism and tremor are neurological manifestations that may occur in malaria as a result of globus pallidi and dentate nuclei involvement.
Euchroeus pellucidus RADOSZKOWSKY 1877
Creators: name: Madl, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Chrysididae
Euchroeus
Euchroeus pellucidus

description: Euchroeus pellucidus RADOSZKOWSKY, 1877
Euchroeus pellucidus RADOSZKOWSKY, 1877: DU BUYSSON 1898b: 522 (tax., Obock).
Euchroeus pellucidus RADOSZKOWSKY, 1877: DU BUYSSON 1898c: 272 (cat. Djibouti).
Euchroeus pellucidus RADOSZKOWSKY, 1877: DU BUYSSON 1899: 162 (Obock, cat. MNHN). Euchroeus pellucidus RADOSZKOWSKY, 1877: MADL & ROSA 2012: 85 (cat. Afr. reg.).
D i s t r i b u t i o n: Obock.
Euchroeus pellucidus is known from the Afrotropical (Djibouti, Tanzania) and
Palaearctic (Egypt, Kazakhstan) regions. The record from Djibouti is not mentioned in BISCHOFF (1913: 29) and KIMSEY & BOHART (1990: 296).
description: Published as part of Madl, Michael, 2018, A preliminary catalogue of the Hymenoptera (Insecta) of the Republic of Djibouti, pp. 907-967 in Linzer biologische Beiträge 50 (2) on pages 915-916, DOI: 10.5281/zenodo.3776452
Treatment of Sydenham’s Chorea: A Review of the Current Evidence
Creators: name: Dean, Shannon L.
name: Singer, Harvey S.
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Chorea
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Immunological adjuvants
subject: Antipsychotic drugs
subject: Neurology

description: Background: Sydenham’s chorea (SC), the neurologic manifestation of rheumatic fever, remains the most prevalent form of chorea in children. Suggested treatments of chorea in SC include prophylactic penicillin, symptomatic (antipsychotic and anticonvulsant) medications, and immunomodulatory therapy (steroids, intravenous immunoglobulin (IVIG), and plasma exchange). In this manuscript, we undertook a systematic review of the published literature to examine the data supporting these therapeutic recommendations.

Methods: A search of PubMed, Embase, Psychinfo, and clinicaltrials.gov was conducted for publications pertaining to the treatment of SC/rheumatic chorea from 1956 to 2016.

Results: Penicillin prophylaxis appears to reduce the likelihood of further cardiac complications and the recurrence rate of chorea. Data on symptomatic therapy for chorea are limited to individual case reports or series and rare comparison studies. The efficacy of steroid use is supported by a single placebo-controlled study and several case series. Information on other immunomodulatory therapies such as IVIG and plasmapheresis are limited to a small number of reports and a single comparison study.

Discussion: Treatment decisions in SC are currently based on the treating physician’s clinical experience, the desire to avoid side effects, and the existence of only limited scientific evidence. Based on a review of the available literature, chorea often improves with symptomatic therapy and immunotherapy tends to be reserved for those who fail to respond. Steroids are beneficial; however, data using IVIG and plasmapheresis are very limited. Larger, well-controlled studies, using standardized assessment scales, are required if therapeutic decisions for SC are to be based on meaningful information.
Analytic study of properties of holographic superconductors in Born-Infeld electrodynamics
Creators: name: Gangopadhyay, Sunandan
name: Roychowdhury, Dibakar
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, based on the Sturm-Liouville eigenvalue problem, we analytically investigate several properties of holographic s-wave superconductors in the background of a Schwarzschild-AdS spacetime in the framework of Born-Infeld electrodynamics. Based on a perturbative approach, we explicitly find the relation between the critical temperature and the charge density and also the fact that the Born-Infeld coupling parameter indeed affects the formation of scalar hair at low temperatures. Higher value of the Born-Infeld parameter results in a harder condensation to form. We further compute the critical exponent associated with the condensation near the critical temperature. The analytical results obtained are found to be in good agreement with the existing numerical results.
description: 12 pages, LateX, To appear in JHEP
Improvement of Post-hypoxic Myoclonus with Bilateral Pallidal Deep Brain Stimulation: A Case Report and Review of the Literature
Creators: name: Ramdhani, Ritesh A.
name: Frucht, Steven J.
name: Kopell, Brian H.
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Brain stimulation--Therapeutic use
subject: Myoclonus
subject: Globus pallidus
subject: Neurosciences
subject: FOS: Clinical medicine

description: Background: Post-hypoxic myoclonus (PHM) is a syndrome that occurs when a patient has suffered hypoxic brain injury. The myoclonus is usually multifocal and generalized, often stemming from both cortical and subcortical origins. In severe cases, pharmacological treatments with antiepileptic medications may not satisfactorily control the myoclonus.

Methods: We present a case of a 23-year-old male with chronic medication refractory PHM following a cardiopulmonary arrest related to an asthmatic attack who improved with bilateral globus pallidus internus (GPi) deep brain stimulation (DBS). We review the clinical features of PHM, as well as the preoperative and postoperative Unified Myoclonus Rating Scale scores and DBS programming parameters in this patient and compare them with the three other published PHM-DBS cases in the literature.

Results: This patient experienced an alleviation of myoclonic jerks at rest and a 39% reduction in action myoclonus with improvement in both positive and negative myoclonus with bilateral GPi-DBS. High frequency stimulation (130 Hz) with amplitudes >2.5 V were needed for the therapeutic response.

Discussion: We demonstrate a robust improvement in a medication refractory PHM patient with bilateral GPi-DBS, and suggest that it is a viable therapeutic option for debilitating post-hypoxic myoclonus.
How Much Do We Know about Adult-onset Primary Tics? Prevalence, Epidemiology, and Clinical Features
Creators: name: Robakis, Daphne
Publisher: name: Columbia University
Year: 2017
Subjects: Tourette syndrome
Tic disorders
Epidemiology
Neurology

description: Background: Tic disorders are generally considered to be of pediatric onset; however, reports of adult-onset tics exist in the literature. Tics can be categorized as either primary or secondary, with the latter being the larger group in adults. Primary or idiopathic tics that arise in adulthood make up a subset of tic disorders whose epidemiologic and clinical features have not been well delineated.

Methods: Articles to be included in this review were identified by searching PubMed, SCOPUS, and Web of Science using the terms adult- and late-onset tics, which resulted in 120 unique articles. Duplicates were removed. Citing references were identified using Google Scholar; all references were reviewed for relevance.

Results: The epidemiologic characteristics, clinical phenomenology, and optimal treatment of adult-onset tics have not been ascertained. Twenty-six patients with adult-onset, primary tics were identified from prior case reports. The frequency of psychiatric comorbidities may be lower in adults than in children, and obsessive compulsive disorder was the most common comorbidity. Adult-onset primary tics tend to wax and wane, occur predominantly in males, are often both motor and phonic in the same individual, and are characterized by a poor response to treatment.

Discussion: We know little about adult-onset tic disorders, particularly ones without a secondary association or cause. They are not common, and from the limited data available, appear to share some but not all features with childhood tics. Further research will be important in gaining a better understanding of the epidemiology and clinical manifestations of this disorder.
Direct access to quantum fluctuations through cross-correlation measurements
Creators: name: Chernii, Iurii
name: Sukhorukov, Eugene V.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Detection of the quantum fluctuations by conventional methods meets certain obstacles, since it requires high frequency measurements. Moreover, quantum fluctuations are normally dominated by classical noise, and are usually further obstructed by various accompanying effects such as a detector backaction. In present work, we demonstrate that these difficulties can be bypassed by performing the cross-correlation measurements. We propose to use a pair of two-level detectors, weakly coupled to a collective mode of an electric circuit. Fluctuations of the current source accumulated in the collective mode induce stochastic transitions in the detectors. These transitions are then read off by quantum point contact (QPC) electrometers and translated into two telegraph processes in the QPC currents. Since both detectors interact with the same collective mode, this leads to a certain fraction of the correlated transitions. These correlated transitions are fingerprinted in the cross-correlations of the telegraph processes, which can be detected at zero frequency, i.e., with a long time measurements. Concerning the dependance of the cross-correlator on the detectors' energy splittings, the most interesting region is at the degeneracy points, where it exhibits a sharp non-local resonance, that stems from higher order processes. We find that at certain conditions the main contribution to this resonance comes from the quantum noise. Namely, while the resonance line shape is weakly broadened by the classical noise, the height of the peak is directly proportional to the square of the quantum component of the noise spectral function.
description: Added discussion of the time scales in the introduction and one figure. 14 pages, 8 figures
Focused Ultrasound for Essential Tremor: Review of the Evidence and Discussion of Current Hurdles
Creators: name: Rohani, Mohammad
name: Fasano, Alfonso
Publisher: name: Columbia University
Year: 2017
Subjects: Tremor
Thalamotomy
Brain--Magnetic resonance imaging
Surgery
Parkinson's disease--Treatment

description: Background. While there is no breakthrough progress in the medical treatment of essential tremor (ET), in the past decades several remarkable achievements happened in the surgical field, such as radiofrequency thalamotomy, thalamic deep brain stimulation and gamma knife thalamotomy. The most recent advance in this area is magnetic resonance-guided focused ultrasound (MRgFUS).

Methods. Purpose of this review is to discuss the new developments and trials of MRgFUS in the treatment of ET and other tremor disorders.

Results. MRgFUS is an incision-less surgery performed without anesthesia and ionizing radiation (no risk of cumulative dose and delayed side effects). Studies have shown the safety and effectiveness of unilateral MRgFUS-thalamotomy in the treatment of ET. It has been successfully used in few patients with Parkinson’s disease-related tremor and fewer patients with Fragile X-associated Tremor/Ataxia Syndrome. Safety and long-term effects of the procedure are still unclear, as temporary and permanent adverse events have been reported as well as reoccurrence of tremor.

Discussion. MRgFUS is a promising new surgical approach with still a number of unknowns and unsolved issues. It represents a valuable option particularly for patients who refused or could not be candidate for other procedures, deep brain stimulation in particular.
A Case of Myoclonus–Dystonia Responding to Low-frequency Pallidal Stimulation
Creators: name: Sarva, Harini
name: Miravite, Joan
name: Swan, Matthew C.
name: Deik, Andres
name: Raymond, Deborah
name: Severt, William L.
name: Kopell, Brian H.
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Myoclonus
subject: Brain stimulation
subject: Dystonia
subject: Neurosciences
subject: FOS: Clinical medicine

description: Background: High frequency pallidal stimulation has been shown to improve various types of dystonia, including myoclonus-dystonia.

Case Report: We report a case of epsilon sarcoglycan mutation-negative myoclonus-dystonia (MD) with response to low frequency bilateral pallidal stimulation.

Discussion: Low frequency pallidal stimulation provides an effective means of treating various dystonias, regardless of genetic status, as in our case, as it provides increased programming options with less adverse effects.
TBC1D24 Mutations in a Sibship with Multifocal Polymyoclonus
Creators: name: Ngoh, Adeline
name: Bras, Jose
name: Guerreiro, Rita
name: McTague, Amy
name: Ng, Joanne
name: Meyer, Esther
name: Chong, W. Kling
name: Boyd, Stewart
name: MacLellan, Linda
name: Kirkpatrick, Martin
name: Kurian, Manju A.
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Myoclonus
subject: Genetics
subject: FOS: Biological sciences
subject: Mutation (Biology)

description: Background: Advances in molecular genetic technologies have improved our understanding of genetic causes of rare neurological disorders with features of myoclonus.

Case Report: A family with two affected siblings, presenting with multifocal polymyoclonus and neurodevelopmental delay, was recruited for whole-exome sequencing following unyielding diagnostic neurometabolic investigations. Compound heterozygous mutations in TBC1D24, a gene previously associated with various epilepsy phenotypes and hearing loss, were identified in both siblings. The mutations included a missense change c.457G>A (p.Glu157Lys), and a novel frameshift mutation c.545del (p.Thr182Serfs*6).

Discussion: We propose that TBC1D24-related diseases should be in the differential diagnosis for children with polymyoclonus.
Fusion products of Kirillov-Reshetikhin modules and the X = M conjecture
Creators: name: Naoi, Katsuyuki
Publisher: name: arXiv
Year: 2011
Subjects: subject: Representation Theory (math.RT)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 17B10, 17B65, 05E15, 81R10

description: In this article, we show in the ADE case that the fusion product of Kirillov-Reshetikhin modules for a current algebra, whose character is expressed in terms of fermionic forms, can be constructed from one-dimensional modules by using Joseph functors. As a consequence, we obtain some identity between fermionic forms and Demazure operators. Since the same identity is also known to hold for one-dimensional sums of nonexceptional type, we can show from these results the X = M conjecture for type $A_n^{(1)}$ and $D_n^{(1)}$.
description: 27 pages, added references and corrected typos
Energy-efficient algorithm design for wireless sensor networks
Creators: name: Shah-Mansouri, Vahid
Publisher: name: University of British Columbia
Year: 2011

description: Wireless sensor networks (WSNs) are composed of inexpensive sensor devices called sensor nodes. Sensors have limited power supply, computational capabilities, and memory. Different types of sensors can measure either temperature, light, sound, or pressure from the environment. Because the sensors have short transmission range, the generated data are gathered via multihop transmissions at a central processor called a sink. In this thesis, we propose several power efficient algorithms for WSNs. First, we formulate the lexicographically optimal commodity lifetime routing problem. We propose the lexicographically optimal node lifetime algorithm, which is suitable for practical implementation. Simulation results show that our proposed algorithm can increase the network lifetime compared to other schemes in the literature. Second, we study the problem of supporting multicast traffic in WSNs with network coding. We formulate the maximum-lifetime minimum-resource coding subgraph problem to study the lifetime-resource tradeoff. Results show that the network lifetime can be substantially increased using our algorithm. Next, we consider the problem of designing feedback mechanisms for WSNs using random linear network coding (RLNC). For an intermediate node, we determine the time at which the node can stop transmission of a particular flow. We propose novel link-by-link and end-to-end feedback mechanisms for RLNC with buffer sharing. Simulation results show that link-by-link feedback is more power-efficient compared to end-to-end feedback. Then, we study the passive loss inference problem in WSNs using RLNC. By inspecting the contents of packets at the sink, the sink can estimate the path loss rates from the sources and intermediate nodes. We propose a passive loss inference with RLNC algorithm. Simulation results show that our algorithm can identify the status of a higher number of links compared to a Bayesian inference algorithm. Finally, we study the problem of cardinality estimation in radio frequency identification systems with several readers. We introduce exclusive estimators to estimate the number of tags located exclusively in the zone of a reader. Then, we propose cardinality estimation algorithms. Our simulation results show that the variance of our proposed estimation algorithms increases linearly with the number of readers while it increases exponentially for existing algorithms.
Deep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid Depression
Creators: name: Patel, Amar S.
Publisher: name: Columbia University
Year: 2017
Subjects: Comorbidity
Parkinson's disease--Patients
Brain stimulation--Therapeutic use
Depression, Mental
Globus pallidus
Tremor

description: Clinical Vignette: A 67-year-old female with advanced Parkinson’s disease (PD), medically refractory tremor, and a history of significant depression presents for evaluation of deep brain stimulation (DBS) candidacy.

Clinical Dilemma: Traditionally, stimulation of the subthalamic nucleus (STN) has been the preferred target for patients with significant PD tremor. However, STN stimulation is avoided in patients with a significant pre-surgical history of mood disorder.

Clinical Solution: Bilateral DBS of the globus pallidus interna led to significant short term improvement in PD motor symptoms, including significant tremor reduction.

Gap in Knowledge: There is insufficient evidence to support or refute clinicians’ traditional preference for STN stimulation in treating refractory PD tremor. Similarly, the available evidence for risk of worsening depression and/or suicidality after STN DBS is mixed. Both questions require further clarification to guide patient and clinician decision-making.
RISER: Raising RISC-V to the cloud
Creators: name: Marazakis, Manolis
name: Louloudakis, Stelios
Publisher: name: Zenodo
Year: 2023

description: First public announcement of the RISER ('RISC-V for Cloud Services') project, in the HiPEACInfo magazine (issue Nr. 68, January 2023).
Charge density dependent nongeminate recombination in organic bulk heterojunction solar cells
Creators: name: Rauh, D.
name: Deibel, C.
name: Dyakonov, V.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Apparent recombination orders exceeding the value of two expected for bimolecular recombination have been reported for organic solar cells in various publications. Two prominent explanations are bimolecular losses with a carrier concentration dependent prefactor due to a trapping limited mobility, and protection of trapped charge carriers from recombination by a donor--acceptor phase separation until reemission from these deep states. In order to clarify which mechanism is dominant we performed temperature and illumination dependent charge extraction measurements under open circuit as well as short circuit conditions at poly(3-hexylthiophene-2,5-diyl):[6,6]-phenyl-C$_{61}$butyric acid methyl ester (P3HT:PC$_{61}$BM) and PTB7:PC$_{71}$BM (Poly[[4,8-bis[(2-ethylhexyl)oxy]benzo[1,2-b:4,5-b']dithiophene-2,6-diyl][3-fluoro-2-[(2-ethylhexyl)carbonyl]thieno[3,4-b]thiophenediyl]]) solar cells in combination with current--voltage characteristics. We show that the charge carrier density $n$ dependence of the mobility $μ$ and the recombination prefactor are different for PC$_{61}$BM at temperatures below 300K and PTB7:PC$_{71}$BM at room temperature. Therefore, in addition to $μ(n)$ a detrapping limited recombination in systems with at least partial donor--acceptor phase separation is required to explain the high recombination orders.
description: 7 pages, 4 figures
title: Remembering Nathan Edelson
Creators: name: Alexander, Don
Publisher: name: Planning Institute of British Columbia
Year: 2023
Subjects: subject: Edelson, Nathan, 194-2023
subject: City planners--Canada

description: Copyright (2023) Planning Institute of British Columbia. The following article originally appeared as: Alexander, D. (2023). Remembering Nathan Edelson. Planning West, 65(4), 28. The PIBC website can be found at: https://www.pibc.bc.ca/
description: Obituary for Nathan Edelsen.
MAGPHYS: a publicly available tool to interpret observed galaxy SEDs
Creators: name: da Cunha, Elisabete
name: Charlot, Stephane
name: Dunne, Loretta
name: Smith, Dan
name: Rowlands, Kate
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a simple, physically-motivated model to interpret consistently the emission from galaxies at ultraviolet, optical and infrared wavelengths. We combine this model with a Bayesian method to obtain robust statistical constraints on key parameters describing the stellar content, star formation activity and dust content of galaxies. Our model is now publicly available via a user-friendly code package, MAGPHYS at www.iap.fr/magphys. We present an application of this model to interpret a sample of ~1400 local (z<0.5) galaxies from the H-ATLAS survey. We find that, for these galaxies, the diffuse interstellar medium, powered mainly by stars older than 10 Myr, accounts for about half the total infrared luminosity. We discuss the implications of this result to the use of star formation rate indicators based on total infrared luminosity.
description: 4 pages, 3 figures, to appear in the Conference Proceedings of IAU Symposium No. 284: The Spectral Energy Distribution of Galaxies, R. J. Tuffs & C.C. Popescu, eds.; MAGPHYS code package available at http://www.iap.fr/magphys
Non-invasive Brain Stimulation for Essential Tremor
Creators: name: Shih, Ludy C.
name: Pascual-Leone, Alvaro
Publisher: name: Columbia University
Year: 2017
Subjects: Brain stimulation--Therapeutic use
Tremor
Movement disorders--Treatment
Motor ability--Physiological aspects

description: Background: There is increasing interest in the use of non-invasive brain stimulation to characterize and potentially treat essential tremor (ET). Studies have used a variety of stimulation coils, paradigms, and target locations to make these observations. We reviewed the literature to compare prior studies and to evaluate the rationale and the methods used in these studies.

Methods: We performed a systematic literature search of the PubMed database using the terms “transcranial,” “noninvasive,” “brain stimulation,” “transcranial magnetic stimulation (TMS),” “transcranial direct current stimulation (tDCS),” “transcranial alternating current stimulation (tACS),” and “essential tremor.”

Results: Single pulses of TMS to the primary motor cortex have long been known to reset tremor. Although there are relatively few studies showing alterations in motor cortical physiology, such as motor threshold, short and long intracortical inhibition, and cortical silent period, there may be some evidence of altered intracortical facilitation and cerebello-brain inhibition in ET. Repetitive TMS, theta burst stimulation, tDCS, and tACS have been applied to human subjects with tremor with some preliminary signs of tremor reduction, particularly in those studies that employed consecutive daily sessions.

Discussion: A variety of stimulation paradigms and targets have been explored, with the increasing rationale an interest in targeting the cerebellum. Rigorous assessment of coil geometry, stimulation paradigm, rationale for selection of the specific anatomic target, and careful phenotypic and physiologic characterization of the subjects with ET undergoing these interventions may be critical in extending these preliminary findings into effective stimulation therapies.
Athermal Phase Separation of Self-Propelled Particles with no Alignment
Creators: name: Fily, Yaouen
name: Marchetti, M. Cristina
Publisher: name: arXiv
Year: 2012
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Cell Behavior (q-bio.CB)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We study numerically and analytically a model of self-propelled polar disks on a substrate in two dimensions. The particles interact via isotropic repulsive forces and are subject to rotational noise, but there is no aligning interaction. As a result, the system does not exhibit an ordered state. The isotropic fluid phase separates well below close packing and exhibits the large number fluctuations and clustering found ubiquitously in active systems. Our work shows that this behavior is a generic property of systems that are driven out of equilibrium locally, as for instance by self propulsion.
description: 5 pages, 4 figures
Additional file 1 of Improving lung cancer risk stratification leveraging whole transcriptome RNA sequencing and machine learning across multiple cohorts
Creators: name: Choi, Yoonha
name: Qu, Jianghan
name: Wu, Shuyang
name: Hao, Yangyang
name: Zhang, Jiarui
name: Ning, Jianchang
name: Yang, Xinwu
name: Lofaro, Lori
name: Pankratz, Daniel G.
name: Babiarz, Joshua
name: Walsh, P. Sean
name: Billatos, Ehab
name: Lenburg, Marc E.
name: Kennedy, Giulia C.
name: McAuliffe, Jon
name: Huang, Jing
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1 Fig. S1: Consort diagram of training and validation sets. Fig. S2: DE analysis on B vs M, smoking status, specimen collection timing, and cohort. Fig. S3: Smoking index score distribution on test set. (a) Box plots of smoking index for smoking status. Scatter plots of smoking index distribution vs smoking-related variables, (b) pack-years and (c) years since quitting smoking. The smoking index is positively correlated with pack-years (Pearson’s correlation = 0.23) and negatively correlated with years since quitting smoking (Pearson’s correlation = − 0.61). Fig. S4: Cross validated model score distribution and model performance by inhaled medication. Model GLM(i + I) is similar to GLM(i), except that the additional clinical feature -- subject currently taking inhaled medication -- is included in the input feature set as main effect and for interactions with genomic features. (a) CV score distribution for within-indication low/intermediate pre-test risk samples, shown separately by subject label and inhaled medication. (b) CV performance for down-classification of within-indication low/intermediate pre-test risk samples. Fig. S5: Pairwise scatter plot of individual model in the final ensemble classifier for samples in test set. Benign and malignant samples are colored in blue and red respectively. The four models are (1) clinical heavy logistic regression model (2) genomic-only SVM model (3) clinical-genomic logistic regression model and (4) hierarchical logistic regression model.
Early Head Tremor in Essential Tremor: A Case Series and Commentary
Creators: name: Louis, Elan D.
name: Badejo, Funmi M.
name: Cristal, Ashley D.
name: Meyers, James
name: Hernandez, Nora
name: Chen, Karen P.
name: Naranjo, Kelly V.
name: Park, Jemin
name: Clark, Lorraine N.
Publisher: name: Columbia University
Year: 2017
Subjects: Tremor
Head
Movement disorders--Diagnosis

description: Background: Classically, the onset of head tremor in essential tremor (ET) patients follows that of hand tremor, such that there is a somatotopic spread of involved areas. Here we present a series of seven self-reportedly “unaffected” relatives of ET cases. These seven were clinically asymptomatic and had normal levels of arm tremor on examination, yet each evidenced a transient head wobble on examination. We estimate the prevalence of this phenotype within the two studies from which cases were ascertained.

Methods: ET cases and their self-reportedly affected and unaffected relatives, enrolled in two family studies, underwent a medical history and videotaped neurological examination.

Results: In seven self-reportedly “unaffected” relatives, a transient and subtle head wobble was seen, always during sustained phonation, speech, or reading aloud. Total tremor score (a measure of arm tremor) ranged from 5 to 12 (i.e., mild tremor within the range of normal). The prevalence of this phenotype of early head tremor was 3.7% in one study and 23.1% in the other.

Discussion: We present a series of seven individuals who had early head tremor in an evolving transition state from normal to ET. These cases raise a number of broad clinical, phenotypic, and pathophysiological issues about ET.