cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The pink adipocytes
Creators: name: Cinti, Saverio
Publisher: name: Firenze University Press
Year: 2017
Subjects: Adipose organ; plasticity; mammary gland; pink adipocytes; electron microscopy

description: Most of white and brown adipocytes, in spite of their well-known different functions: i.e. storing energy (white) and thermogenesis (brown), are contained together in visceral and subcutaneous depots (adipose organ) in all mammals including humans (1, 2). A growing body of evidence suggests that the reason for this anatomical mixture could reside in the fact that adipocytes have peculiar plastic properties allowing them to convert directly each other under appropriate stimuli (3). Under chronic cold exposure white convert into brown to support the need for thermogenesis and under obesogenic diet brown convert into white to satisfy the need of energy storing. Adipocyte population in the mammary gland offers another striking example of adipocyte plasticity: during pregnancy and lactation adipocytes transdifferentiate into milk-producing epithelial cells (we propose to call them: pink adipocytes) and vice versa in the post-lactation period (4, 5, 6). The white into brown transdifferentiation is of great medical interest because the brown phenotype of the adipose organ is associated with obesity resistance and drugs inducing the brown phenotype curb obesity and related disorders (7). We recently showed by transmission electron microscopy that in the post-lactating mammary gland interscapular multilocular adipocytes found close to the mammary alveoli contain milk protein granules. Lineage tracing system allowed showing that the involuting mammary gland of whey acidic protein-Cre/R26R mice, whose secretory alveolar cells express the lacZ gene during pregnancy, contains some X-Gal-stained and uncoupling protein 1 immunoreactive interscapular multilocular adipocytes. These data suggest that during mammary gland involution some milk- secreting epithelial cells in the anterior subcutaneous depot may transdifferentiate to brown adipocytes, highlighting a hitherto unappreciated feature of mouse adipose organ plasticity (8).
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
Sarcoglycan sub-complex in the adipose organ: a molecular and immunofluorescence study
Creators: name: Cinti, Saverio
name: Rizzo, Giuseppina
name: Vermiglio, Giovanna
name: Spoto, Cecilia
name: Centofanti, Antonio
name: Cutroneo, Giuseppina
Publisher: name: Firenze University Press
Year: 2017
Subjects: White adipocyte; brown adipocyte; sarcoglycans; mice; cold-exposure

description: The sarcoglycan sub-complex (SGC) is made up of six glycoproteins which connect the cytoskeleton to the extracellular matrix in skeletal muscle. Recent data show that this complex is also expressed in epithelial tissue such as gingival, breast and prostatic ones [1]. The adipose organ is organized in multiple fat depots consisting of white and brown adipose cells. White adipocytes can store energy in triglycerides; brown adipocytes can dissipate energy for thermogenesis. It has been demonstrated that white adipocytes transdifferentiate to brown adipocytes after cold exposure [3].  In this study we examined the expression of sarcoglycans (SGs) in the adipose organ from two groups of mice: the first group was exposed at 25 C°, as control, and the second one was exposed at low temperature (4 C°) for 24 hours and 4 days. Fat depots from the visceral and interscapular region, but also from the mammary gland, have been examined by histological, immunofluorescence and molecular techniques. Results have shown that SGC is expressed in the adipose organ, both in brown and white adipocytes of mice exposed at 25 C°. The main results is that the expression level of all sarcoglycans increase in cold exposure experiment. For the first time the expression of all SGs in the adipose organ has been demonstrated, both at mRNA and protein levels. Since we found an increase in SGs expression after transdifferentiation from white to brown adipocytes cold exposure induced, we hypothesize that sarcoglycans could be associated with β3 adrenergic receptor; sarcoglycans associations with other receptors, as GABAr, has been already demonstrated in central nervous system. Although that, the function of these glycoproteins in the adipose organ remain still unclear and further investigation are required.
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
Demographics And Case Studies Of Galactic Outflows In The Local Universe
Creators: name: Rupke, David
Publisher: name: Zenodo
Year: 2017

description: Galactic outflows driven by both star formation and active black holes

are an important driver of galaxy evolution. The local universe is a

sensitive laboratory for understanding the scaling relations that

characterize these winds and the physics that govern them. I will

review what we know from statistical studies about the prevalance and

properties of nearby galactic winds and how these properties depend on

those of the host galaxy or power source. I will also highlight

detailed case studies of key objects that illustrate the multiphase

structure of these winds.
Additional file 1 of IDSL_MINT: a deep learning framework to predict molecular fingerprints from mass spectra
Creators: name: Baygi, Sadjad Fakouri
name: Barupal, Dinesh Kumar
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1: Figure S1. Training curves for the lipid annotation model
title: Einfluss verschiedener Verarbeitungsmethoden auf die chemischen, physikalischen und sensorischen Eigenschaften von Äpfeln
Creators: name: Pichler, Manuela
Year: 2008

description: Ziel dieser Arbeit war es, die auf unterschiedliche Weise getrockneten Apfelwürfel hinsichtlich ihrer chemischen, physikalischen und sensorischen Eigenschaften zu vergleichen. Zwei Apfelsorten (Granny Smith, Gala) wurden auf verschiedenen Wegen verarbeitet. Dabei wurde einerseits die Art der Trocknung, andererseits auch die Art der Vorbehandlung variiert. Zum Einsatz kamen die osmotische Vorbehandlung und die Vorbehandlung durch Vakuumimprägnierung in verschiedenen Tauchlösungen. Bei beiden Methoden wurden sowohl die Dauer der Vorbehandlung, als auch die Konzentration der Lösung verändert. Anschließend wurde der Trockensubstanzgehalt, Ascorbinsäuregehalt, aw-Wert, die Textur, Farbe und der Zuckergehalt aller Proben ermittelt und die einzelnen Proben untereinander verglichen. Je sechs Proben einer Apfelsorte wurden zusätzlich zur Bestimmung der Adsorptionsisotherme herangezogen. Zudem wurde mit ausgewählten, getrockneten Apfelstücken eine sensorische Untersuchung durchgeführt. Der gefriergetrocknete, mit Zitronensäurelösung vorbehandelte Granny Smith wurde von den Testern zum beliebtesten Produkt gewählt. Während der gesamten Dauer der Versuche wurde auch der frische Rohstoff regelmäßig hinsichtlich der oben genannten Parameter analysiert. Zusätzlich wurde davon der Reifeindex nach Streif bestimmt.
description: The aim of this work was to compare different types of dried apples concerning their chemical, physical and sensory characteristics. Two types of apples (Granny Smith, Gala) were processed in different ways. On the one hand the type of drying, on the other hand the type of pretreatment varied. Osmotic pretreatment and vacuum impregnation technology with different solutions came into operation. In both methods the duration of pretreatment as well as the concentration of the solutions varied. Then, dry matter, ascorbic acid, aw-value, texture, colour and sugar content of all samples were determined and compared with each other. Six different treated samples of each apple variety were used to obtain the adsorption isotherm. In addition, a sensory testing of selected, dried apple pieces was investigated. The freeze-dried, in citric acid pretreated Granny Smith apple was chosen to be the best product. During the whole period the fresh apples were analysed regarding the parameters mentioned above. Additionally, the Streif-index was determined.
Способы основной обработки агрочерноземов Каменной Степи и их физические свойства.
Creators: name: Гармашов В.М., Чевердин Ю.И.
Publisher: name: «АГРУС»
Year: 2018

description: Было установлено, что уже через год проведения опыта с разными основными обработками на слабоглинистых миграционно-мицелярных агрочерноземах произошли существенные изменения объемной массы и структурного состояния, что необходимо отслеживать для принятия соотвествующих мер по предотвращению деградационных процессов.
Ключевые слова: агрочерноземы, структурное состояние, объемная масса, обработки почв.
Ресурсосберегающая технология на богарных землях юго-востока Казахстана
Creators: name: Кененбаев С.Б., Киреев А.К.
Publisher: name: «АГРУС»
Year: 2018

description: Обработка почвы изменяет, прежде всего, её сложение – плотность, которая является важным показателем физического состояния почвы и рассматривается как один из факторов плодородия почвы. Исследованиями установлены оптимальные значения плотности сложения пахотного слоя серозёмных почв в паровом поле, обеспечивающем лучшее сохранение почвенной влаги. Установлено также, что прямой посев более эффективен на серозёмных почвах легкого механического состава, чем на светло-каштановых почвах вследствие повышения плотности сложения этих почв при исключении их обработки.
Ключевые слова: плотность сложения, обработка почвы, минимализация, прямой посев, пар, богара, сероземы.
Additional file 2 of Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
Creators: name: Calvo-Rodriguez, Maria
name: Kharitonova, Elizabeth K.
name: Snyder, Austin C.
name: Hou, Steven S.
name: Sanchez-Mico, Maria Virtudes
name: Das, Sudeshna
name: Fan, Zhanyun
name: Shirani, Hamid
name: Nilsson, K. Peter R.
name: Serrano-Pozo, Alberto
name: Bacskai, Brian J.
Publisher: name: figshare
Year: 2024
Subjects: Biochemistry
Medicine
Cell Biology
Neuroscience
Chemical Sciences not elsewhere classified

description: Additional file 2: Supplemental Table 1. Analysis of neuronal mitochondrial antioxidant capacity in AD vs. normal aging brain. The expression levels for genes encoding antioxidant enzymes (CAT, GLRX, GPX, GSR, GST, IDH, PRDX, ME, NNT, SOD2, TXN2, and TXNRD) were compared between control (B1, Braak NFT stages 0/I/II) and AD (B3, Braak NFT stages V/VI) individuals of a publicly available human single-nuclei RNA-seq [44]. The average expression level for each gene and group are shown, together with the log fold change and the adjusted p-value of the individual gene models, and the z-scores and the p-values of the mixed models.
Traveling Fronts and the Smoothing of the Collective-Motion Phase Transition in Vibrated Polar Disks
Creators: name: Dauchot, Caleb J. Anderson Olivier
name: Fernandez-Nieves, Alberto
Publisher: name: arXiv
Year: 2024
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: One of the most well known features of active matter is the tendencey of self-propelled particles to undergo system-wide collective motion. With low enough rotational noise or high enough global density, these systems spontaneously break symmetry and transition to a state with nonzero net momentum. The transition is currently understood as discontinuous, with phase coexistence manifesting in terms of dense travelling bands propagating through a dilute background. Here we show that the phase transition appears continuous in experiments with a system of hundreds of polar vibrated disks, and compare the fluctuations in this system to the traveling bands that are present in larger systems. We argue that this difference is due to finite size effects, which are often considered an artifact of simulations in studies with equilibrium systems, but that are of fundamental importance in many systems of self-propelled particles such as those composed of living individuals.
Обоснование ширины захвата  прицепного орудия для щелевания стерневых фонов к тракторам тягового класса 8
Creators: name: Комаров А.П., Лаптев Н.В.
Publisher: name: «АГРУС»
Year: 2018

description: В статье представлены результаты исследований по обоснованию рациональных  ширины захвата прицепного орудия для щелевания стерневых фонов и скорости движения агрегата.
Ключевые слова: щелевание, прицепной щелеватель, ширина захвата, тяговое сопротивление, стерневой фон.
title: Электрические машины. Расчет и моделирование параметров синхронной машины в среде MathCad
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2024

description: В учебном пособии рассматриваются практические и теоретические вопросы изучения дисциплины «Электрические машины» по разделу «Синхронные электрические машины». Приведены подробные методические указания по выполнению практических работ, примеры расчетов, задания, тестовые вопросы и основные теоретические выкладки по изучаемым темам. Содержит подробную методику выполнения расчетов синхронной машины и основные приемы работы с программой MathCAD. Рассматриваются вопросы моделирования параметров синхронного двигателя. Даны подробные методические указания по выполнению работы, примеры расчета, теоретические выкладки. Подготовлено с учетом требований Федерального государственного образовательного стандарта высшего образования. Учебное пособие предназначено для студентов укрупненной группы направлений подготовки «Электро- и теплоэнергетика», выполняющих расчетные и практические задания, курсовой проект (курсовую работу) по дисциплине «Электрические машины». Может быть полезно также при выполнении курсовых работ и проектов по другим специальным дисциплинам и подготовке выпускной квалификационной работы (ВКР).
title: "Frauentheme"’ in der Neuen Freien Presse und in Der Reichspost im Jahr 1919
Creators: name: Lobarzewski, Sandra
Year: 2008

description: Die vorliegende Diplomarbeit beschäftigt sich mit (vermeintlichen) „Frauenthemen“ in den Tageszeitungen „Die Reichpost“ und die „Neue Freie Presse“ im Jahr 1919. Anfangs steht ein historischer Exkurs über die beiden Tageszeitungen, ihre Entstehung und ihre politischen Richtung. Darauf folgt ein Überblick über katholische und bürgerlich liberale Frauenbewegungen in Österreich im Fin de Siècle. Das Hauptaugenmerk der Arbeit liegt auf der quantitativen Analyse der für Frauen relevanten Beiträge beider Tageszeitungen, wobei hier besonders auf die gesellschaftliche und politische Bedeutung des Jahres 1919, in welchem erstmal nach dem Gesetz vom 18.12.1918 auch Frauen zur Wahlurne schreiten durften, eingegangen wird. Durch Gegenüberstellung der Beiträge beider Zeitungen, aber auch der Position der, der Richtung des Blatt nahe stehenden, Frauenbewegungen, wird versucht, ein von den Tageszeitungen transportiertes Frauenleitbild wiederzugeben und somit festzustellen, mit welchen Themen 1919 Frauen angesprochen bzw. nicht angesprochen wurden. Abschließend folgen Kurzbiographien ausgewählter zitierter Autoren und Autorinnen.
An improved numerical simulation methodology for nanoparticle injection through aerodynamic lens systems
Creators: name: Peravali, Surya Kiran
name: Samanta, Amit K.
name: Amin, Muhamed
name: Neumann, Philipp
name: Küpper, Jochen
name: Breuer, Michael
Publisher: name: arXiv
Year: 2025
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Aerosol injectors applied in single-particle diffractive imaging experiments demonstrated their potential in efficiently delivering nanoparticles with high density. Continuous optimization of injector design is crucial for achieving high-density particle streams, minimizing background gas, enhancing X-ray interactions, and generating high-quality diffraction patterns. We present an updated simulation framework designed for the fast and effective exploration of the experimental parameter space to enhance the optimization process. The framework includes both the simulation of the carrier gas and the particle trajectories within injectors and their expansion into the experimental vacuum chamber. A hybrid molecular-continuum-simulation method (DSMC/CFD) is utilized to accurately capture the multi-scale nature of the flow. The simulation setup, initial benchmark results of the coupled approach, and the validation of the entire methodology against experimental data are presented.
title: Интеллектуальные системы и технологии в инструментальной среде Matlab
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2024

description: Учебное пособие содержит рекомендации к выполнению расчетных заданий по дисциплинам «Информатика» и «Интеллектуальные системы и технологии», варианты исходных данных для заданий, а также сведения справочного характера. Приведенный перечень контрольных вопросов позволит узнать степень освоения материала. Даны подробные рекомендации по изучению современных способов и методов проектирования и эксплуатации информационных технологий в различных областях науки и техники. Рассматриваются вопросы реализации в инструментальной среде MATLAB линейных, многослойных нейронных сетей, сетей Кохонена, алгоритмов обучения нейронной сети, а также вопросы изучения гибридной системы класса ANFIS и способы ее построения. Подготовлено с учетом требований Федерального государственного образовательного стандарта высшего образования. Учебное пособие предназначено для студентов укрупненных групп направлений подготовки «Электро- и теплоэнергетика» и «Информатика и вычислительная техника». Может быть полезно также при выполнении курсовых работ и проектов по другим специальным дисциплинами и выпускной квалификационной работы (ВКР).
JWST Observations of Starbursts: Relations between PAH features and CO clouds in the starburst galaxy M 82
Creators: name: Villanueva, V.
name: Bolatto, A. D.
name: Herrera-Camus, R.
name: Leroy, A.
name: Fisher, D. B.
name: Levy, R. C.
name: Böker, T.
name: Boogaard, L.
name: Cronin, S. A.
name: Dale, D. A.
name: Emig, K.
name: De Looze, I.
name: Donnelly, G. P.
name: Lai, T. S. -Y.
name: Lenkic, L.
name: Lopez, L. A.
name: Lopez, S.
name: Meier, D. S.
name: Ott, J.
name: Relano, M.
name: Smith, J. D.
name: Tarantino, E.
name: Veilleux, S.
name: Walter, F.
name: van der Werf, P.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present a study of new 7.7-11.3 $μ$m data obtained with the James Webb Space Telescope Mid-InfraRed Instrument in the starburst galaxy M 82. In particular, we focus on the dependency of the integrated CO(1-0) line intensity on the MIRI-F770W and MIRI-F1130W filter intensities to investigate the correlation between CO content and the 7.7 and 11.3 $μ$m features from polycyclic aromatic hydrocarbons (PAH) in M 82's outflows. To perform our analysis, we identify CO clouds using archival $^{12}$CO($J$=1-0) NOEMA moment 0 map within 2 kpc from the center of M 82, with sizes ranging between $\sim$21 and 270 pc; then, we compute the CO-to-PAH relations for the 306 validated CO clouds. On average, the power-law slopes for the two relations in M 82 are lower than what is seen in local main-sequence spirals. In addition, there is a moderate correlation between $I_{\rm CO(1-0)}$-$I_{\rm 7.7μm} /I_{\rm 11.3μm}$ for most of the CO cloud groups analyzed in this work. Our results suggest that the extreme conditions in M 82 translate into CO not tracing the full budget of molecular gas in smaller clouds, perhaps as a consequence of photoionization and/or emission suppression of CO molecules due to hard radiation fields from the central starburst.
Additional file 1 of Vector competence of Ixodes ricinus instars for the transmission of Borrelia burgdorferi sensu lato in different small mammalian hosts
Creators: name: Lindsø, Lars K.
name: Viljugrein, Hildegunn
name: Mysterud, Atle
Publisher: name: figshare
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1: Table S1. An overview of samples sizes of captured small mammals with live and lethal traps per season between 2018 and 2022 in Son, Viken County, Norway. Table S2. Sequences and adjusted primer set and probe concentrations in respective multiplex real-time quantitative PCR assays for detecting (A) Borrelia burgdorferi s.l. and Anaplasma phagocytophilum and (B) Ixodes ricinus and I. trianguliceps. Table S3. Population level mean and median and interquartile range (IQR) of larval Ixodes ricinus tick burden on individual hosts, proportion of hosts infected with Borrelia burgdorferi s.l., mean proportion of fed I. ricinus larvae, and mean proportion of fed and B. burgdorferi s.l. infected I. ricinus larvae on captured small mammals between 2018 and 2022 in Son, Viken County, Norway. Table S4. Estimates of parameters in generalized linear mixed models on successful feeding in Ixodes ricinus larvae and nymphs and Borrelia burgdorferi s.l. infection in I. ricinus larvae on small mammals captured in southeast Norway (2018–2022) as a function of season and whether the host was found dead or alive.
title: Электрические машины. Расчет и моделирование параметров машин постоянного тока в среде MathCad
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2024

description: В учебном пособии рассматриваются практические и теоретические вопросы изучения дисциплины «Электрические машины» по разделу «Электрические машины постоянного тока». Издание содержит подробную методику выполнения расчетов машин постоянного тока и основные приемы работы с программой MathCAD. Рассматриваются вопросы моделирования параметров машин постоянного тока. Даны подробные методические указания по выполнению работы, примеры расчета, теоретические выкладки. Подготовлено с учетом требований Федерального государственного образовательного стандарта высшего образования. Учебное пособие предназначено для студентов укрупненной группы направлений подготовки «Электро- и теплоэнергетика», выполняющих расчетные и практические задания, курсовой проект (курсовую работу) по дисциплине «Электрические машины». Может быть полезно также при выполнении курсовых работ и проектов по другим специальным дисциплинам и подготовке выпускной квалификационной работы (ВКР).
Harvesting Deformation Modes for Micromorphic Homogenization from Experiments on Mechanical Metamaterials
Creators: name: Maraghechi, S.
name: Rokoš, O.
name: Peerlings, R. H. J.
name: Geers, M. G. D.
name: Hoefnagels, J. P. M.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: A micromorphic computational homogenization framework has recently been developed to deal with materials showing long-range correlated interactions, i.e. displaying patterning modes. Typical examples of such materials are elastomeric mechanical metamaterials, in which patterning emerges from local buckling of the underlying microstructure. Because pattern transformations significantly influence the resulting effective behaviour, it is vital to distinguish them from the overall deformation. To this end, the following kinematic decomposition into three parts was introduced in the micromorphic scheme: (i) a smooth mean displacement field, corresponding to the slowly varying deformation at the macro-scale, (ii) a long-range correlated fluctuation field, related to the buckling pattern at the meso-scale, and (iii) the remaining uncorrelated local microfluctuation field at the micro-scale. The micromorphic framework has proven to be capable of predicting relevant mechanical behaviour, including size effects and spatial as well as temporal mixing of patterns in elastomeric metamaterials, making it a powerful tool to design metamaterials for engineering applications. The long-range correlated fluctuation fields need to be, however, provided a priori as input parameters. The main goal of this study is experimental identification of the decomposed kinematics in cellular metamaterials based on the three-part ansatz. To this end, a full-field micromorphic Integrated Digital Image Correlation (IDIC) technique has been developed. The methodology is formulated for finite-size cellular elastomeric metamaterial specimens deformed in (i) virtually generated images and (ii) experimental images attained during in-situ compression of specimens with millimetre sized microstructure using optical microscopy.
description: 27 pages, 8 figures, abstract shortened to fulfil 1920 character limit
title: Электрические машины постоянного тока
Creators: name: ELS IPR BOOKS
Publisher: name: Профобразование, Ай Пи Ар Медиа
Year: 2024

description: В учебном пособии рассматривается проектирование машин постоянного тока общего назначения, получивших наибольшее применение в современном электроприводе. Подробно изложены методика выполнения расчетов машин постоянного тока и основные приемы работы с программой MathCAD, вопросы моделирования параметров машин постоянного тока. Приведены методические указания, примеры расчета, теоретические выкладки. Подготовлено с учетом требований Федерального государственного образовательного стандарта среднего профессионального образования. Учебное пособие предназначено для студентов, обучающихся по укрупненной группе профессий и специальностей «Электро- и теплоэнергетика», изучающих дисциплину «Электрические машины».
title: Электрические синхронные машины
Creators: name: ELS IPR BOOKS
Publisher: name: Профобразование, Ай Пи Ар Медиа
Year: 2024

description: В учебном пособии рассмотрены вопросы расчета, проектирования и моделирования параметров электрических машин с помощью традиционных средств вычислительной техники и специализированных программ. Подробно изложены методика выполнения расчетов синхронной машины и основные приемы работы с программой MathCAD, вопросы моделирования параметров синхронного двигателя. Приведены методические указания, примеры расчета, теоретические выкладки. Подготовлено с учетом требований Федерального государственного образовательного стандарта среднего профессионального образования. Учебное пособие предназначено для студентов, обучающихся по укрупненной группе профессий и специальностей «Электро- и теплоэнергетика», изучающих дисциплину «Электрические машины».
Voltage-controlled non-axisymmetric vibrations of soft electro-active tubes with strain-stiffening effect
Creators: name: Zhu, F.
name: Wu, B.
name: Destrade, M.
name: Wang, H.
name: Bao, R.
name: Chen, W.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: Material properties of soft electro-active (SEA) structures are significantly sensitive to external electro-mechanical biasing fields (such as pre-stretch and electric stimuli), which generate remarkable knock-on effects on their dynamic characteristics. In this work, we analyze the electrostatically tunable non-axisymmetric vibrations of an incompressible SEA cylindrical tube under the combination of a radially applied electric voltage and an axial pre-stretch. Following the theory of nonlinear electro-elasticity and the associated linearized theory for superimposed perturbations, we derive the nonlinear static response of the SEA tube to the inhomogeneous biasing fields for the Gent ideal dielectric model. Using the State Space Method, we efficiently obtain the frequency equations for voltage-controlled small-amplitude three-dimensional non-axisymmetric vibrations, covering a wide range of behaviors, from the purely radial breathing mode to torsional modes, axisymmetric longitudinal modes, and prismatic diffuse modes. We also perform an exhaustive numerical analysis to validate the proposed approach compared with the conventional displacement method, as well as to elucidate the influences of the applied voltage, axial pre-stretch, and strain-stiffening effect on the nonlinear static response and vibration behaviors of the SEA tube. The present study clearly indicates that manipulating electro-mechanical biasing fields is a feasible way to tune the small-amplitude vibration characteristics of an SEA tube. The results should benefit experimental work on, and design of, voltage-controlled resonant devices made of SEA tubes.
title: Теория электропривода. Расчет параметров электрического привода и выбор его элементов
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2023

description: Учебное пособие содержит рекомендации к выполнению курсового проекта (курсовой работы) по дисциплине «Теория электропривода», варианты исходных данных для заданий на курсовой проект, а также сведения справочного характера. Приведенный список тестов и контрольных вопросов позволит контролировать степень освоения материала. Даны подробные рекомендации по расчету параметров электрического привода и выбору его основных элементов, приведена подробная методика расчета с необходимыми пояснениями, содержание которых будет способствовать формированию требуемых компетенций у студентов. Подготовлено с учетом требований Федерального государственного образовательного стандарта высшего образования. Учебное пособие предназначено для студентов укрупненной группы направлений подготовки «Электро- и теплоэнергетика». Может быть полезно также при выполнении курсовых работ и проектов по другим специальным дисциплинами при выполнении выпускной квалификационной работы (ВКР).
Additional file 1 of Inflammatory markers are associated with infertility prevalence: a cross-sectional analysis of the NHANES 2013–2020
Creators: name: Chen, Yanfen
name: Xu, Huanying
name: Yan, Jianxing
name: Wen, Qidan
name: Ma, Mingjun
name: Xu, Ningning
name: Zou, Haoxi
name: Xing, Xiaoyan
name: Wang, Yingju
name: Wu, Suzhen
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1: Supplementary Figure 1. Distribution of inflammatory markers among individuals included. Legend: (A) SII; (B) LC; (C) PPN; (D) PLR; (E) NLR; (F) LMR were measured in 1×103 cells/μL. SII, systemic immune inflammation index; LC, lymphocyte count; PPN, product of platelet and neutrophil count; PLR, platelet to lymphocyte ratio; NLR, neutrophil to lymphocyte ratio; LMR, lymphocyte to monocyte ratio.
title: Электрические машины переменного тока
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2023

description: В учебном пособии рассматриваются практические и теоретические вопросы изучения дисциплины «Электрические машины» по разделу «Электрические машины переменного тока». Приведены подробные методические указания по выполнению практических работ, примеры расчетов, задания, тестовые вопросы и основные теоретические выкладки по изучаемым темам. Подготовлено с учетом требований Федерального государственного образовательного стандарта высшего образования. Учебное пособие предназначено для студентов укрупненной группы направлений подготовки «Электро- и теплоэнергетика», выполняющих расчетные и практические задания, курсовой проект (курсовую работу) по дисциплине «Электрические машины». Может быть полезно также при выполнении курсовых работ и проектов по другим специальным дисциплинам и подготовке выпускной квалификационной работы (ВКР).
title: Электрические машины. Расчет и моделирование параметров асинхронных электрических машин с короткозамкнутым ротором в среде Mathcad
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2023

description: Учебное пособие содержит подробную методику выполнения расчетов асинхронного электродвигателя с короткозамкнутым ротором и основные приемы работы с программой MathCAD. Рассматриваются вопросы моделирования параметров асинхронного двигателя. Приведены теоретические сведения по выполнению расчетов и работы с программой MathCAD, позволяющие освоить принципы проектирования электрических машин. Даны подробные методические указания по выполнению работы, примеры расчета, теоретические выкладки, а также рекомендации по расчету и моделированию параметров асинхронной электрической машины с короткозамкнутым ротором и выбору ее основных элементов. Изложена подробная методика расчета с необходимыми пояснениями, содержание которых будет способствовать формированию требуемых компетенций у студентов. Подготовлено с учетом требований Федерального государственного образовательного стандарта высшего образования. Учебное пособие предназначено для студентов укрупненной группы направлений подготовки «Электро- и теплоэнергетика», выполняющих курсовой проект (курсовую работу) по дисциплине «Электрические машины». Может быть полезно также при выполнении курсовых работ и проектов по другим специальным дисциплинами при выполнении выпускной квалификационной работы (ВКР).
title: Электрические машины переменного тока
Creators: name: ELS IPR BOOKS
Publisher: name: Профобразование, Ай Пи Ар Медиа
Year: 2023

description: В учебном пособии приведены методические указания по выполнению лабораторных работ, примеры расчетов, заданий, а также рассматриваются основные теоретические вопросы по темам: параллельная работа синхронных генераторов, изучение конструкции трехфазного асинхронного двигателя, однофазные и конденсаторные асинхронные двигатели, изучение конструкции и правил графического построения обмоток машин переменного тока. Подготовлено с учетом требований Федерального государственного образовательного стандарта среднего профессионального образования. Учебное пособие предназначено для студентов, обучающихся по укрупненной группе профессий и специальностей «Электро- и теплоэнергетика», изучающих дисциплину «Электрические машины».
Additional file 2 of Inflammatory markers are associated with infertility prevalence: a cross-sectional analysis of the NHANES 2013–2020
Creators: name: Chen, Yanfen
name: Xu, Huanying
name: Yan, Jianxing
name: Wen, Qidan
name: Ma, Mingjun
name: Xu, Ningning
name: Zou, Haoxi
name: Xing, Xiaoyan
name: Wang, Yingju
name: Wu, Suzhen
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2: Supplementary Figure 2. Distribution of log2-transformed inflammatory markers among individuals included. Legend: (A) log2-transformed SII; (B) log2-transformed LC; (C) log2-transformed PPN; (D)log2-transformed PLR; (E) log2-transformed NLR; (F) log2-transformed LMR. SII, systemic immune inflammation index; LC, lymphocyte count; PPN, product of platelet and neutrophil count; PLR, platelet to lymphocyte ratio; NLR, neutrophil to lymphocyte ratio; LMR, lymphocyte to monocyte ratio.
title: Электрический привод: расчет параметров и выбор его элементов
Creators: name: ELS IPR BOOKS
Publisher: name: Профобразование, Ай Пи Ар Медиа
Year: 2023

description: В учебном пособии рассматриваются основы анализа механической части, выбор и проверка электродвигателя, реализация расчета в среде Mathcad. Даны подробные рекомендации по расчету параметров электрического привода и выбору его основных элементов. Приведены лабораторные работы, примеры решения практических заданий, тесты, вопросы для самопроверки. Подготовлено с учетом требований Федерального государственного образовательного стандарта среднего профессионального образования. Учебное пособие предназначено для студентов, обучающихся по укрупненной группе профессий и специальностей «Электро- и теплоэнергетика», изучающих дисциплину «Основы электропривода».
AutoConf : Automated Configuration of Unsupervised Learning Systems using Metamorphic Testing and Bayesian Optimization
Creators: name: ENTRUST Horizon Europe
Publisher: name: Zenodo
Year: 2023

description: ©2023 IEEE

DOI 10.1109/ASE56229.2023.00094

 

ABSTRACT

Unsupervised learning systems using clustering have gained significant attention for numerous applications due to their unique ability to discover patterns and structures in large unlabeled datasets. However, their effectiveness highly depends on their configuration, which requires domain-specific expertise and often involves numerous manual trials. Specifically, selecting appropriate algorithms and hyperparameters adds to the complexity of the configuration process. In this paper, we propose, apply, and assess an automated approach (AutoConf) for configuring unsupervised learning systems using clustering, leveraging metamorphic testing and Bayesian optimization. Metamorphic testing is utilized to verify the configurations of unsupervised learning systems by applying a series of input transformations. We use Bayesian optimization guided by metamorphic-testing output to automatically identify the optimal configuration. The approach aims to streamline the configuration process and enhance the effectiveness of unsupervised learning systems. It has been evaluated through experiments on six datasets from three domains for anomaly detection. The evaluation results show that our approach can find configurations outperforming the baseline approaches as they achieved a recall of 0.89 and a precision of 0.84 (on average).

 

AUTHORS

Lwin Khin Shar∗, Arda Goknil†, Erik Johannes Husom‡, Sagar Sen°◊, Yan Naing Tun¢“ and Kisub Kim 

School of Computing and Information Systems, Singapore Management University and SINTEF Digital, Norway

Email: ∗lkshar@smu.edu.sg, †arda.goknil@sintef.no, ‡erik.johannes.husom@sintef.no, °◊sagar.sen@sintef.no,

¢“yannaingtun@smu.edu.sg,  kisubkim@smu.edu.sg
O'ZBEK TILINING KELAJAK AVLOD HAYOTIDAGI O'RNI VA ZARURIYATI
Creators: name: Nasirov, Abdullo
name: Komilova, M.M
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada tilning o‘zi haqida qisqacha tushuncha berilgan, o‘zbek tilini o‘rganishda yoshlar duch kelayotgan muammo va qiyinchiliklar tahlil qilingan hamda yoshlar o‘rtasida o‘zbek tilini bilish sifatini oshirish bo‘yicha tavsiyalar berib o‘tilgan.
Dissecting stellar populations with manifold learning I. Validation of the method on a synthetic Milky Way-like galaxy
Creators: name: Neitzel, A. W.
name: Campante, T. L.
name: Bossini, D.
name: Miglio, A.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Different stellar populations may be identified through differences in chemical, kinematic, and chronological properties, suggesting the interplay of various physical mechanisms that led to their origin and subsequent evolution. As such, the identification of stellar populations is key for gaining insight into the evolutionary history of the Milky Way galaxy. This task is complicated by the fact that stellar populations share significant overlap in their chrono-chemo-kinematic properties, hindering efforts to identify and define stellar populations. Our goal is to offer a novel and effective methodology that can provide deeper insight into the nonlinear and nonparametric properties of the multidimensional physical parameters that define stellar populations. For this purpose we explore the ability of manifold learning to differentiate stellar populations with minimal assumptions about their number and nature. Manifold learning is an unsupervised machine learning technique that seeks to intelligently identify and disentangle manifolds hidden within the input data. To test this method, we make use of Gaia DR3-like synthetic stellar samples generated from the FIRE-2 cosmological simulations. These represent red-giant stars constrained by asteroseismic data from TESS. We reduce the 5-dimensional input chrono-chemo-kinematic parameter space into 2-dimensional latent space embeddings generated by manifold learning. We then study these embeddings to assess how accurately they represent the original data and whether they contain meaningful information that can be used to discern stellar populations. We conclude that manifold learning possesses promising abilities to differentiate stellar populations when considering realistic observational constraints.
description: Accepted for publication in A&A; 16 pages, 13 figures, 3 tables; appendix provided via Zenodo
Treatment with r-irisin prevents and recovers disuse-induced bone loss and muscle atrophy
Creators: name: Colaianni, Graziana
name: Lippo, Luciana
name: Pignataro, Paolo
name: Sanesi, Lorenzo
name: Severi, Ilenia
name: Brunetti, Giacomina
name: Mori, Giorgio
name: Colucci, Silvia
name: Reseland, Janne
name: Cinti, Saverio
name: Grano, Maria
Publisher: name: Firenze University Press
Year: 2017

description: Irisin is a hormone-like myokine secreted from skeletal muscle in response to exercise. We previously showed that treatment with recombinant Irisin (r-Irisin) in healthy mice improved cortical bone mass and geometry, supporting the idea that Irisin recapitulates some of the most important benefits of physical exercise on the skeleton and plays protective role on bone health (1). Here we show that treatment with r-Irisin prevented bone loss in hind-limb suspended mice when administered during suspension and induced recovery of bone mass when mice were injected after bone loss due to a suspension period of 4 weeks. MicroCT analysis of femurs showed that r-Irisin preserved both cortical and trabecular bone mineral density, and prevented the dramatic decrease of the trabecular bone volume fraction. Moreover, r-Irisin inhibited muscle mass decline during unloading, keeping proper fiber cross-sectional area. Notably, the decrease in myosin type II expression (MyHC II) in vastus lateralis of unloaded mice treated with r-Irisin was completely prevented. Our data reveal that r-Irisin treatment protects from disuse induced bone loss and muscle atrophy in mice. If these results will translate to humans, they may support a promising clinical strategy for the prevention and treatment of both osteoporosis and sarcopenia, particularly applicable to those patients who cannot perform physical activity, as occurs during aging, immobility and microgravity during space flight missions.
description: Italian Journal of Anatomy and Embryology, Vol. 122, No. 1 (Supplement) 2017
title: Regulation of Alzheimer’s disease-associated phenotypes by the transcription factor REST
Creators: name: Santos Vidal tomas, Mariana
Publisher: name: University of Central Lancashire
Year: 2025

description: Alzheimer’s disease (AD) is the major form of dementia. No cure is currently available, and a better understanding of the molecular and neurobiological mechanisms underlying AD is needed. The RE1-silencing transcription factor (REST) regulates the transcription of several genes in the brain. Recently it has been strongly implicated in AD, healthy ageing and longevity as neuroprotective (a role proposed to be lost in AD), however the exact mechanisms mediating that role are still unclear. The Director of Studies has previously generated a genetically modified conditional knockout (cKO) mouse model lacking REST specifically in neurons of the postnatal forebrain – Rest cKO. Characterization of this mouse model at the morphological and molecular levels is required to gain detailed insights into the role of REST in the brain, especially with relevance to AD. This research project aimed to take the next steps in this direction through a multidisciplinary approach, using biochemical, histological, molecular and computational modelling techniques.

The expression of certain key proteins (GSK3β, p35/p25) involved in one of the hallmarks of Alzheimer’s disease, tau phosphorylation, as well as the levels of phosphorylated tau were found increased in the hippocampus of Rest cKO mice. The levels of an important postsynaptic protein, PSD-95, also appeared to be altered in the brain of Rest cKO mice. Moreover, Rest cKO mice appear to suggest the presence of a very interesting vascular phenotype associated with phospho-tau (pSer202 and pThr205) and its associated kinase GSK3β. The possible presence in Rest cKO mice of common cellular traits of AD, such as neuronal, dendritic and synaptic degeneration and astrocytic activation, was studied through immunohistochemical analysis of the hippocampus. Quantitation of neurons labelled for a neuronal nuclei marker revealed no major neurodegeneration phenotype. However, a mild dendritic degeneration phenotype as well as astrocytic activation was suggested in Rest cKO mice. Analysis of transcriptomic (RNA-seq) results, suggest that postnatal inactivation of Rest down-regulates synaptic activity and neuronal pathways, while also triggering an immune response and enhanced angiogenesis. Furthermore, in an attempt to assist the future design of REST enhancers as potential AD therapeutics, the 3D structures of a) the DNA-binding domain of REST, and b) the consensus Re1 sequence (the REST binding site in the promoter of target genes) were predicted using computational modelling methods.

Overall, postnatal ablation of Rest appears to present a phenotype resembling several aspects of early mild AD, with pivotal mechanisms appearing affected in Rest cKO mice.
Answers to questions about medial layer graphs of self-dual regular and chiral polytopes
Creators: name: Conder, Marston
name: Steinmann, Isabelle
Publisher: name: arXiv
Year: 2024
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 52B15, 05E18

description: An abstract $n$-polytope $\mathcal{P}$ is a partially-ordered set which captures important properties of a geometric polytope, for any dimension $n$. For even $n \ge 2$, the incidences between elements in the middle two layers of the Hasse diagram of $\mathcal{P}$ give rise to the medial layer graph of $\mathcal{P}$, denoted by $\mathcal{G} = \mathcal{G}(\mathcal{P})$. If $n=4$, and $\mathcal{P}$ is both highly symmetric and self-dual of type $\{p,q,p\}$, then a Cayley graph $\mathcal{C}$ covering $\mathcal{G}$ can be constructed on a group of polarities of $\mathcal{P}$. In this paper we address some open questions about the relationship between $\mathcal{G}$ and $\mathcal{C}$ that were raised in a 2008 paper by Monson and Weiss, and describe some interesting examples of these graphs. In particular, we give the first known examples of improperly self-dual chiral polytopes of type $\{3,q,3\}$, which are also among the very few known examples of highly symmetric self-dual finite polytopes that do not admit a polarity. Also we show that if $p=3$ then $\mathcal{C}$ cannot have a higher degree of $s$-arc-transitivity than $\mathcal{G}$, and we present a family of regular $4$-polytopes of type $\{6,q,6\}$ for which the vertex-stabilisers in the automorphism group of $\mathcal{C}$ are larger than those for $\mathcal{G}$.