cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
GENERAL ISSUES OF IMAGE PROCESSING AND ANALYSIS ANDCAPABILITIES OF WEB PROGRAMMING LANGUAGES
Creators: name: Jurayev, Suhrobjon
Publisher: name: Zenodo
Year: 2024

description: In this article, general issues of image processing and analysis andprovides information about the capabilities of web programming languages.Images can be obtained not only in the visible frequency range of electromagnetic waves, but also in the frequency range of acoustic, infrared, ultraviolet, ultrasound, X-ray waves and gamma rays. The means of their creation and preservation are very diverse. Scientific research, production and new methods of creating and storing information in the form of images, as well as the increase in the speed of use and application of modern tools, increase the volume of such information.
Interactions of tetracyclines with milk allergenic protein (casein): a molecular and biological approach
Creators: name: Dantas, Maria Dayanne De A.
name: Silva, Marina De Magalhães
name: Osmar Nascimento Silva
name: Franco, Octavio Luiz
name: Fensterseifer, Isabel Cristina Marques
name: Tenório, Humberto De Araújo
name: Pereira, Hugo Juarez V.
name: Figueiredo, Isis M.
name: Santos, Josué Carinhanha C.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: 60506 Virology

description: Tetracycline (TC), oxytetracycline (OTC), and chlortetracycline (CTC) interactions with the allergenic milk protein casein (CAS) were here evaluated simulating food conditions. The antibiotics assessed interact with CAS through static quenching and form non-fluorescent complexes. At 30 °C, the binding constant (Kb) varied from 0.05 to 1.23 × 106 M−1. Tetracycline interacts with CAS preferably through electrostatic forces, while oxytetracycline and chlortetracycline interactions occur by hydrogen bonds and van der Waals forces. The interaction process is spontaneous, and the magnitude of interaction based on Kb values, followed the order: TC S. aureus, demonstrated that the interaction process possibly alters the biological properties of antibiotics and the own protein, in the food conditions. Communicated by Ramaswamy H. Sarma
Charmonium dissociation at high baryon chemical potential
Creators: name: Tong, Bo
name: Chen, Baoyi
Publisher: name: arXiv
Year: 2022
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the charmonium dissociation in the hot medium with finite baryon chemical potential $μ_B$. Charmonium bound states are dissociated in the medium by the color screening effect and the random scatterings with thermal partons, which are included in the real and imaginary parts of the potential respectively. $J/ψ$ fraction in the $c\bar c$ pair defined to be the quantum overlap between the wave package and the wave function of $J/ψ$ eigenstate decreases with time due to the complex potentials. When $μ_B$ is large compared with the medium temperature, the Deybe mass is increased evidently. We consider $μ_B$-dependent Deybe mass in both real and imaginary parts of the potential to calculate the $J/ψ$ survival probability in the static medium and the Bjorken medium. $J/ψ$ survival probability is reduced evidently by the $μ_B$ effect at low temperatures available in the medium produced in Beam Energy Scan experiments, while this effect becomes not apparent at high temperatures.
description: 6 pages, 6 figures
Curvature-induced changes in the magnetic energy of vortices and skyrmions in paraboloidal nanoparticles
Creators: name: Carvalho-Santos, V. L.
name: Elias, R. G.
name: Fonseca, J. M.
name: Altbir, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Curvature effects are important for a proper description of the properties of magnetic systems. In this paper the exchange and dipolar energy of vortices on a paraboloidal shell is studied. Using analytical calculations it is shown that the in-plane component of vortices has larger energy on a paraboloidal shell than in a planar disk with same thickness. On the other hand, the dipolar energy associated to the vortex core diminishes if the vortex core is on a paraboloidal surface. This reduction in the dipolar energy may cause a vortex pinning mechanism by a paraboloidal shaped defect in a planar nanomagnet. Regarding skyrmions, by using an in-plane anisotropy approximation to the dipolar energy, it is shown that the skyrmion must have its width shrunk in order to diminishes the magnetostatic energy and satisfy geometrical constraints of the system.
Single exciton trapping in an electrostatically defined 2D semiconductor quantum dot
Creators: name: Shanks, Daniel N.
name: Mahdikhanysarvejahany, Fateme
name: Koehler, Michael R.
name: Mandrus, David G.
name: Taniguchi, Takashi
name: Watanabe, Kenji
name: LeRoy, Brian J.
name: Schaibley, John R.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Interlayer excitons (IXs) in 2D semiconductors have long lifetimes and spin-valley coupled physics, with a long-standing goal of single exciton trapping for valleytronic applications. In this work, we use a nano-patterned graphene gate to create an electrostatic IX trap. We measure a unique power-dependent blue-shift of IX energy, where narrow linewidth emission exhibits discrete energy jumps. We attribute these jumps to quantized increases of the number occupancy of IXs within the trap and compare to a theoretical model to assign the lowest energy emission line to single IX recombination.
Rail Infrastructure in Port City -Surabaya, Indonesia
Creators: name: Ravitharan, Ravi
name: LaBrooy, Andrew
name: Widyastuti, Hera
name: Chiu, Wing Kong
Publisher: name: Figshare
Year: 2017
Subjects: subject: 90505 Infrastructure Engineering and Asset Management
subject: FOS: Civil engineering
subject: 150702 Rail Transportation and Freight Services
subject: FOS: Economics and business

description: The aim of this paper is to report on a preliminary study to identify the critical issues in rail infrastructure and assist with the establishment of a firm basis for a large project which will address the asset life extension of the rail infrastructure and the improvement of safety and efficiency of rail transportation in Indonesia.
Foundation Ark: Accruing and Reusing Knowledge for Superior and Robust Performance
Creators: name: Ma, DongAo
name: Pang, Jiaxuan
name: Gotway, Michael B.
name: Liang, Jianming
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Deep learning nowadays offers expert-level and sometimes even super-expert-level performance, but achieving such performance demands massive annotated data for training (e.g., Google's proprietary CXR Foundation Model (CXR-FM) was trained on 821,544 labeled and mostly private chest X-rays (CXRs)). Numerous datasets are publicly available in medical imaging but individually small and heterogeneous in expert labels. We envision a powerful and robust foundation model that can be trained by aggregating numerous small public datasets. To realize this vision, we have developed Ark, a framework that accrues and reuses knowledge from heterogeneous expert annotations in various datasets. As a proof of concept, we have trained two Ark models on 335,484 and 704,363 CXRs, respectively, by merging several datasets including ChestX-ray14, CheXpert, MIMIC-II, and VinDr-CXR, evaluated them on a wide range of imaging tasks covering both classification and segmentation via fine-tuning, linear-probing, and gender-bias analysis, and demonstrated our Ark's superior and robust performance over the SOTA fully/self-supervised baselines and Google's proprietary CXR-FM. This enhanced performance is attributed to our simple yet powerful observation that aggregating numerous public datasets diversifies patient populations and accrues knowledge from diverse experts, yielding unprecedented performance yet saving annotation cost. With all codes and pretrained models released at GitHub.com/JLiangLab/Ark, we hope that Ark exerts an important impact on open science, as accruing and reusing knowledge from expert annotations in public datasets can potentially surpass the performance of proprietary models trained on unusually large data, inspiring many more researchers worldwide to share codes and datasets to build open foundation models, accelerate open science, and democratize deep learning for medical imaging.
description: Best Paper Award Runner-Up at Medical Image Computing and Computer Assisted Intervention (MICCAI) 2023
Coherent feedback in optomechanical systems in the sideband-unresolved regime
Creators: name: Guo, Jingkun
name: Gröblacher, Simon
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Preparing macroscopic mechanical resonators close to their motional quantum groundstate and generating entanglement with light offers great opportunities in studying fundamental physics and in developing a new generation of quantum applications. Here we propose an experimentally interesting scheme, which is particularly well suited for systems in the sideband-unresolved regime, based on coherent feedback with linear, passive optical components to achieve groundstate cooling and photon-phonon entanglement generation with optomechanical devices. We find that, by introducing an additional passive element - either a narrow linewidth cavity or a mirror with a delay line - an optomechanical system in the deeply sideband-unresolved regime will exhibit dynamics similar to one that is sideband-resolved. With this new approach, the experimental realization of groundstate cooling and optomechanical entanglement is well within reach of current integrated state-of-the-art high-Q mechanical resonators.
Defining rail track input conditions using an instrumented revenue vehicle
Creators: name: Te-Liang Chong
name: Awad, Michael
name: Nithurshan Nadarajah
name: Chiu, Wing Kong
name: Lingamanaik, Siva
name: Hardie, Glenn
name: Ravitharan, Ravi
name: Widyastuti, Hera
Publisher: name: Figshare
Year: 2017
Subjects: subject: 150702 Rail Transportation and Freight Services
subject: FOS: Economics and business
subject: 90505 Infrastructure Engineering and Asset Management
subject: FOS: Civil engineering

description: To model the dynamic response of a train running over a given length of rail, the input conditions must be adequately defined. This paper explores the use of an instrumented rail vehicle to assist in the definition of this input condition.
Radiative corrections to the Lorentzian EPRL spin foam propagator
Creators: name: Donà, Pietro
name: Frisoni, Pietropaolo
name: Wilson-Ewing, Edward
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We numerically estimate the divergence of several two-vertex diagrams that contribute to the radiative corrections for the Lorentzian EPRL spin foam propagator. We compute the amplitudes as functions of a homogeneous cutoff over the bulk quantum numbers, fixed boundary data, and different Immirzi parameters, and find that for a class of two-vertex diagrams, those with fewer than six internal faces are convergent. The calculations are done with the numerical framework sl2cfoam-next.
description: 20 pages, 11 figures
Using Instrumented Revenue Vehicles to Inspect Track Integrity and Rolling Stock Performance in a Passenger Network During Peak Times
Creators: name: Lingamanaik, Siva
name: Thompson, Cameron
name: Nirthursan Nadaradjah
name: Ravitharan, Ravi
name: Widyastuti, Hera
name: Chiu, Wing Kong
Publisher: name: Figshare
Year: 2017
Subjects: subject: 150702 Rail Transportation and Freight Services
subject: FOS: Economics and business
subject: 90505 Infrastructure Engineering and Asset Management
subject: FOS: Civil engineering

description: This paper discusses the use of Instrumented Revenue Vehicles, developed by the Institute of Railway Technology at Monash University, to evaluate track condition and assess the dynamic performance of rolling stock during peak operating hours in a passenger network in Indonesia between Lamongon and Surabaya.
Essential Elements Regulating HDAC8 Inhibition: A Classification Based Structural Analysis and Enzyme-Inhibitor Interaction Study of Hydroxamate Based HDAC8 Inhibitors
Creators: name: Suvankar Banerjee
name: Sk. Abdul Amin
name: Nilanjan Adhikari
name: Jha, Tarun
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 60506 Virology

description: Histone deacetylase 8 (HDAC8) expressions are correlated with a variety of cancer and tumor conditions. For the pathophysiological contributions of HDAC8, it is classified as an important target for cancer research. The hydroxamate derivatives are identified as more efficient HDAC8 inhibitors. However, strong chelating properties of hydroxamate group with the catalytic zinc ion of HDAC8 resulted in some demerits. Hence, in this current study, classification based chemoinformatic approaches including Bayesian modeling and recursive partitioning studies were conducted on a large and diverse set of 607 hydroxamates having less, very poor to high HDAC8 inhibitory properties. The main motto of this study is to identify and analyze the pivotal structural features of the cap and linker moieties required to obtain better HDAC8 inhibition. Moreover, a scrutiny of the HDAC8 crystal bound inhibitors was performed to correlate enzyme-inhibitor interactions with important molecular features resulted from these two classification-based models. The approach may be used to design novel HDAC8 inhibitors.
No scale SUGRA SO(10) derived Starobinsky Model of Inflation
Creators: name: Garg, Ila
name: Mohanty, Subhendra
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We show that a supersymmetric renormalizable theory based on gauge group SO(10) and Higgs system {\bf {10 $\oplus$ 210 $\oplus$ 126 $\oplus$ $\overline{\bf 126}$}} with no scale supergravity can lead to a Starobinsky kind of potential for inflation. Successful inflation is possible in the cases where the potential during inflation corresponds to $SU(3)_C \times SU(2)_L \times SU(2)_R \times U(1)_{B-L}$, $SU(5)\times U(1)$ and flipped $SU(5)\times U(1)$ intermediate symmetry with a suitable choice of superpotential parameters. The reheating in such a scenario can occur via non perturbative decay of inflaton i.e. through "preheating". After the end of reheating, when universe cools down, the finite temperature potential can have a minimum which corresponds to MSSM.
description: 6 pages, 2 figures, Replaced with version to appear in Phys Lett B
Solving the multi-messenger puzzle of the AGN-starburst composite galaxy NGC 1068
Creators: name: Eichmann, Björn
name: Oikonomou, Foteini
name: Salvatore, Silvia
name: Dettmar, Ralf-Jürgen
name: Tjus, Julia Becker
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Multi-wavelength observations indicate that some starburst galaxies show a dominant non-thermal contribution from their central region. These active galactic nuclei (AGN)-starburst composites are of special interest, as both phenomena on their own are potential sources of highly-energetic cosmic rays and associated gamma-ray and neutrino emission. In this work, a homogeneous, steady-state two-zone multi-messenger model of the non-thermal emission from the AGN corona as well as the circumnuclear starburst region is developed and subsequently applied to the case of NGC 1068, which has recently shown some first indications of high-energy neutrino emission. Here, we show that the entire spectrum of multi-messenger data - from radio to gamma-rays including the neutrino constraint - can be described very well if both, starburst and AGN corona, are taken into account. Using only a single emission region is not sufficient.
Effect of bromine atom on the different tautomeric forms of microhydrated 5-bromouracil, in the DNA: RNA microhelix and in the interaction with human proteins
Creators: name: M. Alcolea Palafox
name: S. M. Chalanchi
name: J. Isasi
name: R. Premkumar
name: A. Milton Franklin Benial
name: V.K. Rastogi
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: This study focuses on the effects of the bromine atom on the molecular structure parameters in the main tautomeric forms of 5-bromouracil (5BrU), and as well, its effect on hydration and on the Watson-Crick (WC) pairs as compared to uracil molecule. The influence of the bromine atom when it was inserted in uracil and uridine molecules was studied in several environments. The hydration effect on the molecular structure and energies of the main tautomeric forms of 5BrU was analyzed by considering a variable number of water molecules in explicit form surrounding 5BrU. Up to 30 water molecules were used to simulate the first and second hydration shells. About two hundred clusters were optimized. The “mutagenic” 2-hydroxy-4-oxo (U2) enol tautomer of 5BrU, but not of uracil, was absolutely favored over the keto form in clusters with more than 20 explicit water molecules. For all calculations, B3LYP and M06-2X Density Functional (DFT) Methods have been used. In addition, the effect of the bromine atom when it was inserted into the natural and reverse Watson-Crick pairs uridine-adenosine was determined, and counterpoise (CP) corrected interaction energies were calculated. The effect of the bromine atom was analyzed in several DNA:RNA hybrid microhelices. Different backbone and helical parameters were calculated and compared. The bromine atom destabilizes its base pair, with a remarkable increase in the rise parameter (Dz) corresponding to the microhelix, and to a slight increase in the diameter (d). Molecular docking calculations were also carried out with 5BrU for targeted proteins associated with diabetes, hepatocellular carcinoma, and breast and lung cancers.The molecular docking analysis confirms that the 5BrU molecule may play an important role as a promising inhibitor against breast cancer.
Introducción a la didáctica universitaria y el currículo
Creators: name: Rivas, Jorge Luis Hilario
Publisher: name: Zenodo
Year: 2023
Subjects: didactica
curriculo

description: La didáctica universitaria es una disciplina que se enfoca en el estudio y desarrollo de los procesos de enseñanza y aprendizaje en el contexto de la educación superior. Esta disciplina busca desarrollar estrategias pedagógicas efectivas que permitan a los docentes facilitar el aprendizaje de los estudiantes y alcanzar los objetivos del currículo universitario.
Observation of low-field Feshbach resonances between $^{161}$Dy and $^{40}$K
Creators: name: Ye, Zhu-Xiong
name: Canali, Alberto
name: Soave, Elisa
name: Kreyer, Marian
name: Yudkin, Yaakov
name: Ravensbergen, Cornelis
name: Kirilov, Emil
name: Grimm, Rudolf
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We report on the observation of Feshbach resonances at low magnetic field strength (below 10 G) in the Fermi-Fermi mixture of $^{161}$Dy and $^{40}$K. We characterize five resonances by measurements of interspecies thermalization rates and molecular binding energies. As a case of particular interest for applications, we consider a resonance near 7.29 G, which combines accurate magnetic tunability and access to the universal regime of interactions with experimental simplicity. We show that lifetimes of a few 100 ms can be achieved for the optically trapped, resonantly interacting mixture. We also demonstrate the hydrodynamic expansion of the mixture in the strongly interacting regime and the formation of DyK Feshbach molecules. Our work opens up new experimental possibilities in view of mass-imbalanced superfluids and related phenomena.
In vitro anticancer activity of binuclear Ru(II) complexes with Schiff bases derived from 5-substituted salicylaldehyde and 2-aminopyridine with notably low IC50 values
Creators: name: Kahrović, Emira
name: Zahirović, Adnan
name: Pavelić, Sandra Kraljević
name: Turkušić, Emir
name: Harej, Anja
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: The binuclear Ru(II) complexes with Schiff bases derived from 5-chlorosalicyladehyde and 2-aminopyridine and its 5-substituted salicylideneimine homologues were tested in vitro against cervical carcinoma (HeLa), metastatic colorectal adenocarcinoma (SW620), lung adenocarcinoma (A549), breast adenocarcinoma (MCF-7), and human lung fibroblast (WI-38) cell lines. All compounds showed strong antiproliferative activity with extremely low IC50 values. The compounds expressed strong activity against gram-positive bacteria, Staphylococcus aureus and Enterococcus faecalis.
Beratung und Supervision in der Bildung von Lehrer*innen
Creators: name: Bender, Saskia
name: Griewatz, Hans-Peter
name: Klenner, Denise
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2022

description: Beratung und Supervision scheinen methodisch und systematisch jene Lücke zu füllen, die sich ergibt, wenn von Lehrkräften verlangt wird, die sich eröffnenden schulpädagogischen Handlungsoptionen insbesondere hinsichtlich der Förderung oder Einschränkung möglicher Lern- und Bildungsprozesse von Schüler*innen vor dem Hintergrund bestehender und erworbener Wissensbestände zu reflektieren. In diesem Zusammenhang werden zunehmend beratende Tätigkeiten insbesondere auch im Rahmen der Diskurse und Bemühungen um Kooperation, Diversität, Inklusion und multiprofessionelle Zusammenarbeit über alle drei Phasen der Lehrer*innenbildung hinweg adressiert und damit auch verstärkt Gegenstand wissenschaftlicher Auseinandersetzungen. Mit dem vorliegenden Themenheft, welches Beiträge der gleichnamigen Tagung aus dem Jahr 2021 dokumentiert, werden von den Autor*innen theoretisch-systematische und empirische Erkundungen vorgenommen, die vor allem auch aktuelle Entwicklungen und Maßnahmen in der Lehrer*innenbildung darstellen und reflektieren.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Bd. 4 Nr. 3 (2022): Beratung und Supervision in der Bildung von Lehrer*innen
Pulsations in B-type supergiants with masses $M<20M_\odot$ before and after core helium ignition
Creators: name: Ostrowski, J.
name: Daszyńska-Daszkiewicz, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Evolutionary tracks and pulsational analysis of models with masses of 13-18 $M_\odot$ are presented. We address two important questions. The first one deals with one of the most unresolved problems in astrophysics, i.e., the existence of a blue loop after core helium ignition; the so called "to loop or not to loop" problem. We show that inward overshooting from the outer convective zone in the red giant phase is prerequisite for the development of the blue loop. Our second question concerns pulsational instability of models in the core helium burning phase. We present for the first time that models on the blue loop can have unstable modes driven by the $κ$ mechanism operating in the $Z-$bump. Contrary to post-main sequence models in the shell hydrogen burning phases, pulsational instability of the blue loop models depends mainly on effective temperature and metallicity is of secondary importance. Finally, we try to interpret the oscillation spectrum of the blue supergiant HD 163899, the only member of the SPBsg class, and to get some clue on the evolutionary status of the star.
description: accepted for publication in MNRAS, 9 pages, 9 figures
Detection of Condensed Vehicle Gas Exhaust in LiDAR Point Clouds
Creators: name: Piroli, Aldi
name: Dallabetta, Vinzenz
name: Walessa, Marc
name: Meissner, Daniel
name: Kopp, Johannes
name: Dietmayer, Klaus
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: LiDAR sensors used in autonomous driving applications are negatively affected by adverse weather conditions. One common, but understudied effect, is the condensation of vehicle gas exhaust in cold weather. This everyday phenomenon can severely impact the quality of LiDAR measurements, resulting in a less accurate environment perception by creating artifacts like ghost object detections. In the literature, the semantic segmentation of adverse weather effects like rain and fog is achieved using learning-based approaches. However, such methods require large sets of labeled data, which can be extremely expensive and laborious to get. We address this problem by presenting a two-step approach for the detection of condensed vehicle gas exhaust. First, we identify for each vehicle in a scene its emission area and detect gas exhaust if present. Then, isolated clouds are detected by modeling through time the regions of space where gas exhaust is likely to be present. We test our method on real urban data, showing that our approach can reliably detect gas exhaust in different scenarios, making it appealing for offline pre-labeling and online applications such as ghost object detection.
description: Accepted for ITSC2022
Comparison of multi-mode Hong-Ou-Mandel interference and multi-slit interference
Creators: name: Guo, Yan
name: Yang, Zi-Xiang
name: Zeng, Zi-Qi
name: Ding, Chunling
name: Shimizu, Ryosuke
name: Jin, Rui-Bo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Hong-Ou-Mandel (HOM) interference of multi-mode frequency entangled states plays a crucial role in quantum metrology. However, as the number of modes increases, the HOM interference pattern becomes increasingly complex, making it challenging to comprehend intuitively. To overcome this problem, we present the theory and simulation of multi-mode-HOM interference (MM-HOMI) and compare it to multi-slit interference (MSI). We find that these two interferences have a strong mapping relationship and are determined by two factors: the envelope factor and the details factor. The envelope factor is contributed by the single-mode HOM interference (single-slit diffraction) for MM-HOMI (MSI). The details factor is given by $\sin(Nx)/ \sin(x)$ ($[\sin(Nv)/\sin(v)]^2$) for MM-HOMI (MSI), where $N$ is the mode (slit) number and $x (v)$ is the phase spacing of two adjacent spectral modes (slits). As a potential application, we demonstrate that the square root of the maximal Fisher information in MM-HOMI increases linearly with the number of modes, indicating that MM-HOMI is a powerful tool for enhancing precision in time estimation. We also discuss multi-mode Mach-Zehnder interference, multi-mode NOON-state interference, and the extended Wiener-Khinchin theorem. This work may provide an intuitive understanding of MM-HOMI patterns and promote the application of MM-HOMI in quantum metrology.
description: 16 pages, 7 figures
Análisis y diseño del currículo universitario
Creators: name: Rivas, Jorge Luis Hilario
Publisher: name: Zenodo
Year: 2023
Subjects: didactica
curriculo

description: Es un proceso complejo que implica la identificación de objetivos de aprendizaje, la definición de contenidos y actividades de enseñanza, la selección de estrategias de evaluación y la determinación de la estructura del programa.
Discovery and identification of putative adenosine kinase inhibitors as potential anti-epileptic agents from structural insights
Creators: name: Pakhuri Mehta
name: Malik, Ruchi
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: The seizure controlling activity of human adenosine kinase (AK) has been identified as a promising target for the development of small-molecule inhibitors to be used as potential anti-epileptic agents. Overexpression of AK has been considered as a pathologic hallmark of epilepsy. However, the exploration of AK for the treatment of epilepsy still remains a challenge in drug discovery. In a pursuit to recognize novel inhibitors of AK, a structure-based virtual screening study based on the molecular docking analysis of the compounds of Asinex database was performed. Crystal structure of human AK in complex with inhibitor revealed the crucial ligand–protein interactions (Asn14, Asn18, Ser65 and Phe170) within the active site and offers opportunities for further development of the potential anti-epileptic agents. Overall, 20 novel diverse potential hits appear to be important scaffolds for the design of novel AK inhibitors with better docking scores, dG bind scores with in silico desired pharmacokinetic parameters and synthetic accessibility scores than the co-crystallized ligand. Computational hits obtained through validated virtual screening protocol (superposition and enrichment) followed by simulation studies, quantum mechanics with better pharmacokinetic performance and hit optimization study provides in silico evidence for the applicability of these valuable tools in drug discovery and towards the development of a better therapeutic regime of epilepsy. Communicated by Ramaswamy H. Sarma
Inertial focusing of a dilute suspension in pipe flow
Creators: name: Aouane, Othmane
name: Sega, Marcello
name: Bäuerlein, Bastian
name: Avila, Kerstin
name: Harting, Jens
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The dynamics of rigid particle suspensions in a wall-bounded laminar flow present several non-trivial and intriguing features, including particle ordering, lateral transport, and the appearance of stable, preferential locations like the Segré-Silberberg annulus. The formation of more than one annulus is a particularly puzzling phenomenon that is still not fully explained. Here, we present numerical simulation results of a dilute suspension of particles in (periodic) pipe flow based on the lattice Boltzmann and the discrete element methods (DEM). Our simulations provide access to the full radial position history of the particles while traveling downstream. This allows to accurately quantify the transient and steady states. We observe the formation of the secondary, inner annulus and show that its position invariably shifts toward the Segré-Silberberg one if the channel is sufficiently long, proving that it is, in fact, a transient feature for Reynolds numbers (Re) up to 600. We quantify the variation of the channel focusing length ($L_s/2R$) with Re. Interestingly and unlike the theoretical prediction for a point-like particle, we observe that $L_s/2R$ increases with Re for both the single particle and the suspension.
Not our kind of crowd! How partisan bias distorts perceptions of political bots on Twitter (now X)
Creators: name: Lueders, Adrian
name: Reiss, Stefan
name: Dinkelberg, Alejandro
name: MacCarron, Pádraig
name: Quayle, Michael
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: Social bots, employed to manipulate public opinion, pose a novel threat to digital societies. Existing bot research has emphasized technological aspects while neglecting psychological factors shaping human–bot interactions. This research addresses this gap within the context of the US-American electorate. Two datasets provide evidence that partisanship distorts (a) online users' representation of bots, (b) their ability to identify them, and (c) their intentions to interact with them. Study 1 explores global bot perceptions on through survey data from N=452 Twitter (now X) users. Results suggest that users tend to attribute bot-related dangers to political adversaries, rather than recognizing bots as a shared threat to political discourse. Study 2 (N=619) evaluates the consequences of such misrepresentations for the quality of online interactions. In an online experiment, participants were asked to differentiate between human and bot profiles. Results indicate that partisan leanings explained systematic judgement errors. The same data suggest that participants aim to avoid interacting with bots. However, biased judgements may undermine this motivation in praxis. In sum, the presented findings underscore the importance of interdisciplinary strategies that consider technological and human factors to address the threats posed by bots in a rapidly evolving digital landscape.
MOESM1 of TIPS: a system for automated image-based phenotyping of maize tassels
Creators: name: Gage, Joseph
name: Miller, Nathan
name: Spalding, Edgar
name: Kaeppler, Shawn
name: Leon, Natalia De
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 1. List of parameters accepted by TIPS, their default values, and descriptions.
Strukturlogik supervisorischer Praxis
Creators: name: Leser, Christoph
name: Jornitz, Sieglinde
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2022

description: Im Beitrag wird ein strukturtheoretisches Modell der Supervision als Professionalisierungsinstrument in der Lehrer*innenbildung entfaltet. Dieses stützt sich auf die Strukturtheorie des professionalisierten Handelns von Ulrich Oevermann und bindet es ein in die pädagogische Theorie des Unterrichtens nach Andreas Gruschka. Anhand einer Supervisionssitzung, die in einer Förderschule im Förderschwerpunkt Sprache aufgezeichnet, verschriftet und mittels der Interpretationstechnik der Objektiven Hermeneutik ausgewertet wurde, wird das Strukturmodell der Supervision im Rahmen der Lehrer*innenbildung mit Rückgriff auf das analysierte Material herausgearbeitet und kritisch diskutiert.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Bd. 4 Nr. 3 (2022): Beratung und Supervision in der Bildung von Lehrer*innen
Echtzeit Datengewinnung, -auswertung und -visualisierung im Hörsaal. Das Audience Response System FreeQuizDome und mögliche Einsatzszenarien im akademischen Kontext.
Creators: name: Senst, Erik
Publisher: name: Kolloquium Wissensinfrastruktur
Year: 2014

description: Kolloquium Wissensinfrastruktur, Sommersemester 2014
Neutrino mass and charged lepton flavor violation in an extended left-right symmetric model
Creators: name: Majumdar, Chayan
name: Senapati, Supriya
name: Sankar, S. Uma
name: Yajnik, Urjit A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider an $U(1)_{L_μ-L_τ}$ extended left-right symmetric gauge theory where the neutrino masses are generated through inverse seesaw mechanism. In this model the muon $(g-2)$ anomaly is accounted for by the mediation of $Z_{μτ}$, the gauge boson of $U(1)_{L_μ- L_τ}$ symmetry. The symmetries of the model require the light neutrino mass matrix to have a particular two-zero texture, which leads to non-trivial constraints in the minimum neutrino mass. In addition, the model predicts observable charged lepton flavor violation in $μ-τ$ sector.
description: 21 pages, 2 figures, 2 tables, Version accepted in Nucl. Phys. B
Molecular dynamics and computational study of Mannich-based coumarin derivatives: Potent tyrosine kinase inhibitor
Creators: name: Sahoo, Chita Ranjan
name: Paidesetty, Sudhir Kumar
name: Budheswar Dehury
name: Padhy, Rabindra Nath
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: The manifestation of bacterial UTI (Urinary Tract Infection) has been predominantly endemic, globally; eventually, the development of new UTI anti-bacterial agent(s) remains the call of the day. Herein, two series of Mannich-based 4-hydroxy coumarin derivatives, 7a-m and 8a-m were designed by suitable heterocyclic amines condensed with aldehydes. The synthesized molecules were interpreted by 1H and 13C NMR spectral analyses with in vitro antibacterial studies. The compound, 4-hydroxy-3-((4-hydroxy-3-methoxyphenyl)(morpholino)methyl)-2H-chromen-2-one 8l was the significant derivative against pathogenic bacteria Staphylococcus aureus and Escherichia coli with MIC values 12.50 and 25µM, respectively. Computational assessments with the Lipinski’s rule of five, ADMET properties and molecular docking studies revealed that analogues, 7f, 7l, 8d, 8j and 8k could be potent druggable molecules with significant binding affinity towards bacterial tyrosine kinase, as target. To understand the mode of binding and intrinsic stabilities of potent receptor-ligand complexes, each system was subjected molecular dynamics simulations for 100 ns. Inter-molecular contact analysis and intrinsic hydrogen-bond stability portrayed the analogues 8l form a number of non-bonded contacts with the receptor tyrosine kinase being mostly dominated by electrostatic and hydrophobic contacts. The results from the present structure-based designing approach might be a valuable tool towards identification of a new antibacterial drug candidate(s) against UTI in near future. List of Abbreviations: 4-HC, 4-hydroxy coumarin; ADMET, absorption, distribution, metabolism, excretion, toxicity; DCE, 1,2-dichloroethane; DCM, dichloromethane; DMSO, dimethyl sulfoxide ; MD, molecular dynamics; MIC, minimum inhibitory concentration; NMR, nuclear magnetic resonance; NPT, isothermal isobaric ensembles; NVT, canonical ensembles; PCA, principal component analysis; PDB, protein data bank; Rg, radius gyration, RMSF, root mean square fluctuations RSMD, root mean square deviation; UTI, Urinary Tract Infection.
Number of workers in each threshold class and raw data of the experiment 2 from Response threshold variance as a basis of collective rationality
Creators: name: Yamamoto, Tatsuhiro
name: Hasegawa, Eisuke
Publisher: name: Figshare
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Table S1 and S2 show number of workers in each threshold class through 3 measurements, and Table S3 and S4 show raw data of the experiment 2.
Neural network scoring for efficient computing
Creators: name: Waltsburger, Hugo
name: Libessart, Erwan
name: Ren, Chengfang
name: Kolar, Anthony
name: Guinvarc'h, Regis
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: I.2; I.4; C.4

description: Much work has been dedicated to estimating and optimizing workloads in high-performance computing (HPC) and deep learning. However, researchers have typically relied on few metrics to assess the efficiency of those techniques. Most notably, the accuracy, the loss of the prediction, and the computational time with regard to GPUs or/and CPUs characteristics. It is rare to see figures for power consumption, partly due to the difficulty of obtaining accurate power readings. In this paper, we introduce a composite score that aims to characterize the trade-off between accuracy and power consumption measured during the inference of neural networks. For this purpose, we present a new open-source tool allowing researchers to consider more metrics: granular power consumption, but also RAM/CPU/GPU utilization, as well as storage, and network input/output (I/O). To our best knowledge, it is the first fit test for neural architectures on hardware architectures. This is made possible thanks to reproducible power efficiency measurements. We applied this procedure to state-of-the-art neural network architectures on miscellaneous hardware. One of the main applications and novelties is the measurement of algorithmic power efficiency. The objective is to allow researchers to grasp their algorithms' efficiencies better. This methodology was developed to explore trade-offs between energy usage and accuracy in neural networks. It is also useful when fitting hardware for a specific task or to compare two architectures more accurately, with architecture exploration in mind.
description: 5 pages, 5 figures
Funktionen von Supervision in der Bildung von Lehrer*innen
Creators: name: Klenner, Denise
name: Griewatz, Hans-Peter
name: Bender, Saskia
name: Heinrich, Martin
Publisher: name: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung.
Year: 2022

description: Der Beitrag nimmt Supervision in der Bildung von Lehrer*innen aus einer empirisch-rekonstruktiven Perspektive in den Blick. Zunächst werden Ergebnisse aus Fallrekonstruktionen vorgestellt, die auf Mitschnitten von Gruppensupervisionssitzungen im Bachelorstudium basieren, welche – begleitend zu einer Praxisphase –die Förderung von (Selbst-)Reflexions- und Professionalisierungsprozessen ermöglichen sollten. Hier zeigt sich, dass Lehramtsstudierende das Setting faktisch zu einem Raum umfunktionieren, in dem vor allem Entlastung, Stabilisierung und Vergemeinschaftung erfahren werden sollen. Eine supervisorische Fallarbeit, die explizit reflexiv angelegt ist und impliziert, dass Studierende sich immer auch selbst „zum Fall“ machen, steht der Bedürfnislage der Studierenden damit diametral entgegen. Die daraus resultierende Vermutung, dass Supervision als Professionalisierungsimpuls sinnvoll erst in späteren Phasen der Lehrer*innenbildung zu verorten wäre, muss angesichts weiterer Fallrekonstruktionen von Interviews mit berufserfahrenen Lehrkräften zu deren Erfahrungen mit Supervision ebenfalls relativiert werden. Auch hier werden andere Aspekte von Supervision als positiv und hilfreich gerahmt: wiederum die Stabilisierung, im Sinne von Selbstermächtigung und Unterstützung bei der Wiederherstellung von Ordnung (Regelschule), sowie Diagnostik und fachliche Weiterbildung (Förderschule). Supervisorische Praxis erscheint damit hier in einer funktionalen Dimension, wobei die rekonstruierten Funktionen auf eine klare Lokalisierung des Problemkerns im Außen zielen (typischerweise in problematischen, „schwierigen“ Schüler*innen) sowie auf Vereindeutigung und Komplexitätsreduktion – anstatt auf tatsächliche Selbstreflexion, die auch Offenheit für Irritationen und eine selbstkritische Perspektive auf das eigene Wahrnehmen, Deuten und professionelle Handeln zuließe. Im Anschluss an diese Ergebnisse stellen sich Fragen nach der Konturierung von Supervision im Kontext Lehrer*innenbildung und Schule, die auf der einen Seite die Bedürfnisse (angehender) Lehrer*innen ernst nimmt, ohne auf der anderen Seite ihr selbstreflexives Potenzial einzubüßen.
description: PraxisForschungLehrer*innenBildung. Zeitschrift für Schul- und Professionsentwicklung., Bd. 4 Nr. 3 (2022): Beratung und Supervision in der Bildung von Lehrer*innen
In-silico design of peptide inhibitors of K-Ras target in cancer disease
Creators: name: Mehreen Ghufran
name: Rehman, Ashfaq Ur
name: Masaud Shah
name: Ayaz, Muhammad
name: Ng, Ho Leung
name: Wadood, Abdul
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Cancer
subject: Computational Biology

description: Cancer is a leading cause of death, over one million individuals analyzed, and around 500,000 deaths happen due to cancer every year alone in the United States. The Ras is a significant protein in the signaling transduction pathways and has a leading role in cell proliferation. Above 30% of all human tumors arises due to the mutations in genes that encode a Ras protein that operate signaling cascades necessary for malignant transformation, tumor angiogenesis, and metastasis. The Ras gene family comprised of 36 total genes in human. The N-Ras, K-Ras, and H-Ras are accounted for to assume noticeable function in human cancer. The mutation in K-Ras protein is most commonly found in tumors. K-Ras is the most crucial driver in lung and pancreatic cancers. Among the mutations of N-Ras, H-Ras, and K-Ras, the mutant K-Ras is the most prevalent target for the development of Lungs, colon, and pancreatic cancers. The study aimed to develop the peptide inhibitors of the K-Ras G12D. The crystal structure of the mutant K-Ras/R11.1.6 G12D complex was retrieved from the protein databank. The protein R11.1.6 directly blocks interaction with Raf and diminishes signaling through the Raf-MEK-ERK signaling pathway. Here, in this study, we designed novel peptides from the truncated reference peptide (R11.1.6) through residue scan methodology. The top ten designed peptides (based on binding free energies) were subjected to molecular dynamics simulations using AMBER to evaluate stability. Our results indicate that the top ten selected peptides have strong interactions with K-Ras than the reference peptide (R11.1.6) and have the potency to prevent the binding of Raf and K-Ras. Communicated by Ramaswamy H. Sarma