cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens
Creators: name: Nightingale, James. W.
name: Smith, Russell J.
name: He, Qiuhan
name: O'Riordan, Conor M.
name: Kegerreis, Jacob A.
name: Amvrosiadis, Aristeidis
name: Edge, Alastair C.
name: Etherington, Amy
name: Hayes, Richard G.
name: Kelly, Ash
name: Lucey, John R.
name: Massey, Richard J. Massey Richard J.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Supermassive black holes (SMBHs) are a key catalyst of galaxy formation and evolution, leading to an observed correlation between SMBH mass $M_{\rm BH}$ and host galaxy velocity dispersion $σ_{\rm e}$. Outside the local Universe, measurements of $M_{\rm BH}$ are usually only possible for SMBHs in an active state: limiting sample size and introducing selection biases. Gravitational lensing makes it possible to measure the mass of non-active SMBHs. We present models of the $z=0.169$ galaxy-scale strong lens Abell~1201. A cD galaxy in a galaxy cluster, it has sufficient `external shear' that a magnified image of a $z = 0.451$ background galaxy is projected just $\sim 1$ kpc from the galaxy centre. Using multi-band Hubble Space Telescope imaging and the lens modeling software $\texttt{PyAutoLens}$ we reconstruct the distribution of mass along this line of sight. Bayesian model comparison favours a point mass with $M_{\rm BH} = 3.27 \pm 2.12\times10^{10}\,$M$_{\rm \odot}$ (3$σ$ confidence limit); an ultramassive black hole. One model gives a comparable Bayesian evidence without a SMBH, however we argue this model is nonphysical given its base assumptions. This model still provides an upper limit of $M_{\rm BH} \leq 5.3 \times 10^{10}\,$M$_{\rm \odot}$, because a SMBH above this mass deforms the lensed image $\sim 1$ kpc from Abell 1201's centre. This builds on previous work using central images to place upper limits on $M_{\rm BH}$, but is the first to also place a lower limit and without a central image being observed. The success of this method suggests that surveys during the next decade could measure thousands more SMBH masses, and any redshift evolution of the $M_{\rm BH}$--$σ_{\rm e}$ relation. Results are available at https://github.com/Jammy2211/autolens_abell_1201.
description: Accepted in MNRAS, 27 pages, 22 figures
(3255) Louis Albert Reunert
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Urban geomorphology of the Vistula River valley in Warsaw
Creators: name: Wierzbicki, Grzegorz
name: Ostrowski, Piotr
name: Bartold, Piotr
name: Bujakowski, Filip
name: Falkowski, Tomasz
name: Osiński, Piotr
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Using ALS LIDAR DEM and OpenStreetMap data we visualise in ArcGIS the geomorphic features of a large, lowland river which flows through the area impacted by urbanisation of a big city – the capital of Poland. We present on one map the main geomorphological surfaces and their exact boundaries: valley edge, terrace front and floodplain juxtaposed with buildings and the main transportation corridors. We identify convex aeolian and fluvial landforms: dunes, levees, sandy lobes including crevasse splays, ridges between swales, sandy bars, islands; and concave erosional landforms: floodplain channels, crevasse channels, oxbow lakes, palaeo-meanders, tributary channels, and chute channels. We draw implications for flood management, geo-archaeology geo-heritage conservation. We search for traces of extreme flood events in the Holocene, also on the higher terraces which the river developed by its deposition in the Pleistocene.
An integrated sea-land approach for analyzing forms, processes, deposits and the evolution of the urban coastal belt of Cagliari
Creators: name: Porta, Marco
name: Buosi, Carla
name: Trogu, Daniele
name: Ibba, Angelo
name: De Muro, Sandro
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Using a comprehensive cartographic product, this paper aims to illustrate the evolution of the urban geomorphological setting of the urban coastal belt of Cagliari (southern Sardinia, Italy, western Mediterranean Sea). The geomorphological map (1:14,000) presented herein summarizes different data (e.g. urban development, anthropogenic features, geomorphological elements, recent deposits, sedimentological distribution, hydrodynamics and ecological components) acquired through an integrated sea-land approach and a multidisciplinary-multitemporal investigation. The main significant environmental changes are linked to urbanization, the development of port infrastructures (embankments along the shoreline and the construction of the canal harbour), remediation work and filling activities, and the hardening of dune and beach systems and cliffs. These man-made interventions have increased the vulnerability of the shore zones to flood hazards and risks, which are linked to sea-level rises and global warming.
THE ADVENTURE OF THE WESTERN STAR by Agatha Christie, The Gunston Trust on Ipad
Creators: name: Hill
Publisher: name: Zenodo
Year: 2024

description: THE ADVENTURE OF THE WESTERN STAR by Agatha Christie, The Gunston Trust

 

 

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THE ADVENTURE OF THE WESTERN STAR

Agatha Christie, The Gunston Trust

Page: 44

Format: pdf, ePub, mobi, fb2

ISBN: 9798881154714

Publisher: Barnes & Noble Press

 

Free pdb ebook download THE ADVENTURE OF THE WESTERN STAR FB2 English version 9798881154714 by Agatha Christie, The Gunston Trust

PDF THE ADVENTURE OF THE WESTERN STAR by Agatha Christie, The Gunston Trust EPUB Download Share link here and get free ebooks to read online. Share link here and get free ebooks to read online. Format PDF | EPUB | MOBI ZIP RAR files. You should be able to download your books shared forum THE ADVENTURE OF THE WESTERN STAR EPUB PDF Download Read Agatha Christie, The Gunston Trust Review. You can download your books fast THE ADVENTURE OF THE WESTERN STAR. Fans love new book EPUB THE ADVENTURE OF THE WESTERN STAR By Agatha Christie, The Gunston Trust PDF Download.

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Comparisons between different techniques for measuring mass segregation
Creators: name: Parker, Richard J.
name: Goodwin, Simon P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We examine the performance of four different methods which are used to measure mass segregation in star-forming regions: the radial variation of the mass function $\mathcal{M}_{\rm MF}$; the minimum spanning tree-based $Λ_{\rm MSR}$ method; the local surface density $Σ_{\rm LDR}$ method; and the $Ω_{\rm GSR}$ technique, which isolates groups of stars and determines whether the most massive star in each group is more centrally concentrated than the average star. All four methods have been proposed in the literature as techniques for quantifying mass segregation, yet they routinely produce contradictory results as they do not all measure the same thing. We apply each method to synthetic star-forming regions to determine when and why they have shortcomings. When a star-forming region is smooth and centrally concentrated, all four methods correctly identify mass segregation when it is present. However, if the region is spatially substructured, the $Ω_{\rm GSR}$ method fails because it arbitrarily defines groups in the hierarchical distribution, and usually discards positional information for many of the most massive stars in the region. We also show that the $Λ_{\rm MSR}$ and $Σ_{\rm LDR}$ methods can sometimes produce apparently contradictory results, because they use different definitions of mass segregation. We conclude that only $Λ_{\rm MSR}$ measures mass segregation in the classical sense (without the need for defining the centre of the region), although $Σ_{\rm LDR}$ does place limits on the amount of previous dynamical evolution in a star-forming region.
description: 13 pages, 9 figures, accepted for publication in MNRAS
Figure S7: Differential metabolite abundances and enzyme associated gene expression in the pyrimidine metabolism pathway between control and aposymbiotic tsetse from Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveals highly integrated physiological networks.
Creators: name: Bing, XiaoLi
name: Attardo, Geoffrey M.
name: Vigneron, Aurelien
name: Aksoy, Emre
name: Scolari, Francesca
name: Malacrida, Anna
name: Weiss, Brian L.
name: Aksoy, Serap
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Physiology

description: Metabolite data was derived from bacteriome specific metabolomic analysis. Differential enzyme transcription was derived from transcriptomic data from whole guts of control and aposymbiotic flies. Enzymes are represented as rectangles and defined by their KEGG Enzyme ID numbers and metabolites/cofactors are represented as circles and are labeled with metabolite names. Enzyme and metabolite symbols are colored to reflect their increased (blue) or decreased (red) expression (for enzymes) or abundance (for metabolites). Light blue/red symbols represent changes in abundance approaching significance (p-value between 0.1 - 0.05). Green symbols reflect Wigglesworthia derived enzymes/metabolites. Numerical representation of metabolite data is in Table S7 and enzyme gene expression data is in Table S9.
Refinement of schizophrenia GWAS loci using methylome-wide association data
Creators: name: Nerella, Srilaxmi
name: Hultman, Christina M.
name: Clark, Shaunna L.
name: Adkins, Daniel E.
name: Sullivan, Patrick F.
name: Kim, Yunjung
name: Kumar, Gaurav
name: van den Oord, Edwin J.C.G.
name: Chan, Robin
name: Shabalin, Andrey A.
name: Aberg, Karolina A.
name: Xie, Linying
name: McClay, Joseph L.
name: Magnusson, Patrik K.E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Recent genome-wide association studies (GWAS) have made substantial progress in identifying disease loci. The next logical step is to design functional experiments to identify disease mechanisms. This step, however, is often hampered by the large size of loci identified in GWAS that is caused by linkage disequilibrium (LD) between SNPs. In this study, we demonstrate how integrating methylome-wide association study (MWAS) results with GWAS findings can narrow down the location for a subset of the putative casual sites. We use the disease schizophrenia as an example. To handle “data analytic” variation we first combined our MWAS results with two GWAS meta-analyses (N=32,143 and 21,953), that had largely overlapping samples but different data analysis pipelines, separately. Permutation tests showed significant overlapping association signals between GWAS and MWAS findings. This significant overlap justified prioritizing loci based on the concordance principle. To further ensure that the methylation signal was not driven by chance, we successfully replicated the top three methylation findings near genes SDCCAG8, CREB1 and ATXN7 in an independent sample using targeted pyrosequencing. In contrast to the SNPs in the selected region, the methylation sites were largely uncorrelated explaining why the methylation signals implicated much smaller regions (median size 78bp). The refined loci showed considerable enrichment of genomic elements of possible functional importance and suggested specific hypotheses about schizophrenia etiology. Several hypotheses involved possible variation in transcription factor binding efficiencies.
{pdf download} Close to Home: A Novel by Michael Magee
Creators: name: Fontaine
Publisher: name: Zenodo
Year: 2024

description: Close to Home: A Novel by Michael Magee

 

 

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Close to Home: A Novel

Michael Magee

Page: 288

Format: pdf, ePub, mobi, fb2

ISBN: 9780374608323

Publisher: Farrar, Straus and Giroux

 

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Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans
Creators: name: Le Marchand, Loïc
name: Haile, Robert
name: Casey, Graham
name: Fortini, Barbara K.
name: Wang, Hansong
name: Pande, Mala
name: Keku, Temitope O.
name: Sandler, Robert S.
name: Newcomb, Polly A.
name: Stram, Daniel O.
name: Burnett, Terrilea
name: Haiman, Christopher A.
name: Amos, Christopher I.
name: Henderson, Brian E.
name: West, Dee W.
name: Berndt, Sonja I.
name: Blot, William J.
name: Signorello, Lisa B.
name: Kolonel, Laurence N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Genome-wide association studies of colorectal cancer (CRC) in Europeans and Asians have identified 21 risk susceptibility regions [29 index single-nucleotide polymorphisms (SNPs)]. Characterizing these risk regions in diverse racial groups with different linkage disequilibrium (LD) structure can help localize causal variants. We examined associations between CRC and all 29 index SNPs in 6597 African Americans (1894 cases and 4703 controls). Nine SNPs in eight regions (5q31.1, 6q26-q27, 8q23.3, 8q24.21, 11q13.4, 15q13.3, 18q21.1 and 20p12.3) formally replicated in our data with one-sided P-values <0.05 and the same risk directions as reported previously. We performed fine-mapping of the 21 risk regions (including 250 kb on both sides of the index SNPs) using genotyped and imputed markers at the density of the 1000 Genomes Project to search for additional or more predictive risk markers. Among the SNPs correlated with the index variants, two markers, rs12759486 (or rs7547751, a putative functional variant in perfect LD with it) in 1q41 and rs7252505 in 19q13.1, were more strongly and statistically significantly associated with CRC (P < 0.0006). The average per allele risk was improved using the replicated index variants and the two new markers (odds ratio = 1.14, P = 6.5 × 10−16) in African Americans, compared with using all index SNPs (odds ratio = 1.07, P = 3.4 × 10−10). The contribution of the two new risk SNPs to CRC heritability was estimated to be 1.5% in African Americans. This study highlights the importance of fine-mapping in diverse populations.
[Pdf/ePub] Of Knights and Books and Falling In Love by Rita A. Rubin download ebook
Creators: name: Vanderhoof
Publisher: name: Zenodo
Year: 2024

description: Of Knights and Books and Falling In Love by Rita A. Rubin

 

 

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Of Knights and Books and Falling In Love

Rita A. Rubin

Page: 204

Format: pdf, ePub, mobi, fb2

ISBN: 9780645092868

Publisher: Rita A. Rubin

 

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Overview

Jayce has little memory of life before entering servitude to the Dark Lord, and no hope of ever escaping. Until he meets Alexius, the knight with a heart of gold. He offers Jayce, his enemy, a chance to break free of the Dark Lord's clutches, and Jayce is not about to let such an opportunity pass. When the war comes to an end, Jayce finds himself finally free, with Alexius's help, and surrounded by a new world of opportunity. And the prospect of a new love. The more time Jayce spends with Alexius, the more he finds himself falling for this knight in shining armour.
FRATS: Functional Regression Analysis of DTI Tract Statistics
Creators: name: Gilmore, John H.
name: Zhu, Hongtu
name: Tang, Niansheng
name: Styner, Martin
name: Liu, Zhexing
name: Lin, Weili
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Diffusion tensor imaging (DTI) provides important information on the structure of white matter fiber bundles as well as detailed tissue properties along these fiber bundles in vivo. This paper presents a functional regression framework, called FRATS, for the analysis of multiple diffusion properties along fiber bundle as functions in an infinite dimensional space and their association with a set of covariates of interest, such as age, diagnostic status and gender, in real applications. The functional regression framework consists of four integrated components: the local polynomial kernel method for smoothing multiple diffusion properties along individual fiber bundles, a functional linear model for characterizing the association between fiber bundle diffusion properties and a set of covariates, a global test statistic for testing hypotheses of interest, and a resampling method for approximating the p-value of the global test statistic. The proposed methodology is applied to characterizing the development of five diffusion properties including fractional anisotropy, mean diffusivity, and the three eigenvalues of diffusion tensor along the splenium of the corpus callosum tract and the right internal capsule tract in a clinical study of neurodevelopment. Significant age and gestational age effects on the five diffusion properties were found in both tracts. The resulting analysis pipeline can be used for understanding normal brain development, the neural bases of neuropsychiatric disorders, and the joint effects of environmental and genetic factors on white matter fiber bundles.
[download pdf] Woom by Duncan Ralston
Creators: name: Floyd
Publisher: name: Zenodo
Year: 2024

description: Woom by Duncan Ralston

 

 

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Woom

Duncan Ralston

Page: 144

Format: pdf, ePub, mobi, fb2

ISBN: 9781988819174

Publisher: Shadow Work Publishing

 

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Overview

"Trust me when I say, this is messed up." - MATT SHAW, author of Sick B*stards. "I believe pain lingers," Angel said. "Do I believe in spirits? In the supernatural? Probably not." The Lonely Motel holds many dark secrets... and Room 6 just might possess the worst of them all. Angel knows all about pain. His mother died in this room. He's researched its history. Today he's come back to end it, no matter the cost, once and for all. Shyla, a plus-sized escort, thinks the stories Angel tells her can't be true. Secrets so vile, you won't want to let them inside you. But the Lonely Motel doesn't forget. It doesn't forgive. And it always claims its victim. "This book is a wet dream of abnormal sexual psychology." - Mort Stone, My Indie Muse WARNING: Don't buy this book if you have a weak stomach, if you're easily disturbed, or if you're looking for a light horror read. THIS IS NOT THAT BOOK. Seriously. You've been warned.
A Markov Random Field Groupwise Registration Framework for Face Recognition
Creators: name: Shen, Dinggang
name: Liao, Shu
name: Chung, Albert C.S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: In this paper, we propose a new framework for tackling face recognition problem. The face recognition problem is formulated as groupwise deformable image registration and feature matching problem. The main contributions of the proposed method lie in the following aspects: (1) Each pixel in a facial image is represented by an anatomical signature obtained from its corresponding most salient scale local region determined by the survival exponential entropy (SEE) information theoretic measure. (2) Based on the anatomical signature calculated from each pixel, a novel Markov random field based groupwise registration framework is proposed to formulate the face recognition problem as a feature guided deformable image registration problem. The similarity between different facial images are measured on the nonlinear Riemannian manifold based on the deformable transformations. (3) The proposed method does not suffer from the generalizability problem which exists commonly in learning based algorithms. The proposed method has been extensively evaluated on four publicly available databases: FERET, CAS-PEAL-R1, FRGC ver 2.0, and the LFW. It is also compared with several state-of-the-art face recognition approaches, and experimental results demonstrate that the proposed method consistently achieves the highest recognition rates among all the methods under comparison.
(3254) Frederick Reunert
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Download PDF The Fire Never Goes Out: A Memoir in Pictures by Noelle Stevenson
Creators: name: Deloach
Publisher: name: Zenodo
Year: 2024

description: The Fire Never Goes Out: A Memoir in Pictures by Noelle Stevenson

 

 

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The Fire Never Goes Out: A Memoir in Pictures

Noelle Stevenson

Page: 208

Format: pdf, ePub, mobi, fb2

ISBN: 9780062278265

Publisher: HarperCollins Publishers

 

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The Fire Never Goes Out: A Memoir in Pictures 9780062278265 Fire Never Goes Out : a Memoir in Pictures. Author. Noelle Stevenson. Format. Trade Paperback. Language. English. Topic. Comics & Graphic Novels / Biography  The Fire Never Goes Out: A Memoir in Pictures - LightSail Read The Fire Never Goes Out: A Memoir in Pictures by Stevenson, Noelle, lexile & reading level: , (ISBN: 9780062278289). Book enhanced with curriculum  The Fire Never Goes Out: A Memoir in Pictures Paperback The Fire Never Goes Out collects several years of Tumblr doodles and reflection by Noelle Stevenson. It is a powerful, very personal book that follows the  Fire Never Goes Out: A Memoir in Pictures HC - Atomic Empire Fire Never Goes Out: A Memoir in Pictures HC From Noelle Stevenson, the New York Times bestselling author-illustrator of Nimona, comes a captivating, honest  Graphic Novel Review: the fire never goes out: a memoir in Graphic Novel Review: the fire never goes out: a memoir in pictures by noelle stevenson. Posted on April 29, 2021 at 12:14 pm by Gene Ambaum. Fire Never Goes Out A Memoir In Pictures TP - Midtown Comics Fire Never Goes Out A Memoir In Pictures TP From Noelle Stevenson comes a captivating, honest graphic novel memoir that finds her turning an important  The Fire Never Goes Out: A Memoir in Pictures (Paperback) From Noelle Stevenson, the New York Times bestselling author-illustrator of Nimona, comes a captivating, honest illustrated memoir that  A Memoir in Pictures by Noelle Stevenson (2021, Trade Find many great new & used options and get the best deals for The Fire Never Goes Out : A Memoir in Pictures by Noelle Stevenson (2021, Trade Paperback) at  A Memoir in Pictures, Paperback by Stevenson, Noelle, B Fire Never Goes Out : A Memoir in Pictures, Paperback by Stevenson, Noelle, ISBN 0062278266, ISBN-13 9780062278265, Brand New, Free shipping in the US The  The Fire Never Goes Out: A Memoir in Pictures Archives - Wait 0:01-1:02:01: “How does it feel to be the new publisher of DC Comics?” asks Graeme McMillan of Jeff Lester, and if you're wondering if that's a reference of  The Fire Never Goes Out: A Memoir in Pictures (Paperback) Description. From Noelle Stevenson, the New York Times bestselling author-illustrator of Nimona, comes a captivating, honest illustrated memoir that finds Publisher: Quill Tree BooksPublication Date: July 6th, 2021Related Editions (all): Kobo eBook (March 3rd,
YaxAB, a Yersinia enterocolitica Pore-Forming Toxin Regulated by RovA
Creators: name: Borst, Luke B.
name: Millera, Virginia L.
name: Lin, Carolina P.
name: Wagner, Nikki J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: ABSTRACT The transcriptional regulator RovA positively regulates transcription of the Yersinia enterocolitica virulence gene inv . Invasin, encoded by inv , is important for establishment of Y. enterocolitica infection. However, a rovA mutant is more attenuated for virulence than an inv mutant, implying that RovA regulates additional virulence genes. When the Y. enterocolitica RovA regulon was defined by microarray analysis, YE1984 and YE1985 were among the genes identified as being upregulated by RovA. Since these genes are homologous to Xenorhabdus nematophila cytotoxin genes xaxA and xaxB , we named them yaxA and yaxB , respectively. In this work, we demonstrate the effects of YaxAB on the course of infection in the murine model. While a yaxAB mutant (Δ yaxAB ) is capable of colonizing mice at the same level as the wild type, it slightly delays the course of infection and results in differing pathology in the spleen. Further, we found that yaxAB encode a probable cytotoxin capable of lysing mammalian cells, that both YaxA and YaxB are required for cytotoxic activity, and that the two proteins associate. YaxAB-mediated cell death occurs via osmotic lysis through the formation of distinct membrane pores. In silico tertiary structural analysis identified predicted structural homology between YaxA and proteins in pore-forming toxin complexes from Bacillus cereus (HBL-B) and Escherichia coli (HlyE). Thus, it appears that YaxAB function as virulence factors by inducing cell lysis through the formation of pores in the host cell membrane. This characterization of YaxAB supports the hypothesis that RovA regulates expression of multiple virulence factors in Y. enterocolitica .
Comparison of Multiple Enzyme Activatable Near-Infrared Fluorescent Molecular Probes for Detection and Quantification of Inflammation in Murine Colitis Models:
Creators: name: Ding, Shengli
name: Blue, Randal E.
name: Lund, Pauline K.
name: Morgan, Douglas R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Activatable near-infrared fluorescent (NIRF) probes have been used for ex vivo and in vivo detection of intestinal tumors in animal models. We hypothesized that NIRF probes activatable by cathepsins or MMPs will detect and quantify dextran sulphate sodium (DSS) induced acute colonic inflammation in wild type (WT) mice or chronic colitis in IL-10 null mice ex vivo or in vivo.
Table S1: Transcriptomic and metabolomic datasets utilized in this study from Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveals highly integrated physiological networks
Creators: name: Bing, XiaoLi
name: Attardo, Geoffrey M.
name: Vigneron, Aurelien
name: Aksoy, Emre
name: Scolari, Francesca
name: Malacrida, Anna
name: Weiss, Brian L.
name: Aksoy, Serap
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Physiology

description: This table contains the individual RNA-seq and metabolomic data sets utilized in this paper. Associated SRA numbers of tables are listed.
(3253) Samuel Harry Reunert
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
How Market Structure Drives Commodity Prices
Creators: name: Li, Bin
name: Wong, K. Y. Michael
name: Chan, Amos H. M.
name: So, Tsz Yan
name: Heimonen, Hermanni
name: Wei, Junyi
name: Saad, David
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Finance (q-fin.GN)
subject: Physics and Society (physics.soc-ph)
subject: General Economics (econ.GN)
subject: FOS: Economics and business
subject: FOS: Physical sciences

description: We introduce an agent-based model, in which agents set their prices to maximize profit. At steady state the market self-organizes into three groups: excess producers, consumers and balanced agents, with prices determined by their own resource level and a couple of macroscopic parameters that emerge naturally from the analysis, akin to mean-field parameters in statistical mechanics. When resources are scarce prices rise sharply below a turning point that marks the disappearance of excess producers. To compare the model with real empirical data, we study the relations between commodity prices and stock-to-use ratios of a range of commodities such as agricultural products and metals. By introducing an elasticity parameter to mitigate noise and long-term changes in commodities data, we confirm the trend of rising prices, provide evidence for turning points, and indicate yield points for less essential commodities.
description: 17 pages, 5 figures, 1 table, 15 pages of Supporting Information
Immunization Rates and Vaccine Beliefs Among Patients with Inflammatory Bowel Disease: An Opportunity for Improvement
Creators: name: Farraye, Francis A.
name: Kappelman, Michael D.
name: Sandler, Robert S.
name: Long, Millie D.
name: Calderwood, Audrey H.
name: Wasan, Sharmeel K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Immunosuppressive agents used to treat inflammatory bowel disease (IBD) can increase the risk for infections, several of which are preventable through vaccination. Our study aimed to describe vaccine utilization by immunosuppression status, examine reasons for vaccine refusal, and identify characteristics associated with lack of influenza vaccination in IBD patients.
The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention:
Creators: name: Jobin, Christian
name: Midura-Kiela, Monica
name: Ghishan, Fayez K.
name: Ramalingam, Rajalakshmy
name: Larmonier, Claire B.
name: Chase, John H.
name: Shehab, Kareem W.
name: Kiela, Pawel R.
name: Harrison, Christy A.
name: Caporaso, J. Gregory
name: Besselsen, David G.
name: Mcfadden, Rita Marie T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Intestinal microbiota influences the progression of colitis-associated colorectal cancer (CAC). With diet being a key determinant of the gut microbial ecology, dietary interventions are an attractive avenue for the prevention of CAC. Curcumin is the most active constituent of the ground rhizome of the Curcuma Longa plant, which has been demonstrated to have anti-inflammatory, anti-oxidative and anti-proliferative properties.
(3252) John Reunert
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Papia civitas gloriosa: urban geomorphology for a thematic itinerary on geocultural heritage in Pavia (Central Po Plain, N Italy)
Creators: name: Pelfini, Manuela
name: Brandolini, Filippo
name: D’Archi, Sara
name: Pellegrini, Luisa
name: Bollati, Irene
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: The interaction between geomorphological processes and anthropogenic activities produces an impressive association of geomorphological and archaeological heritage in urban contexts. We analyzed the urban geomorphology and the geo- and cultural heritage in the town of Pavia (N Italy). The city is located in a strategic position, on a series of fluvial terraces where the Romans founded a colony, probably in the place of an Iron Age Gaul settlement. In Medieval Times and the Modern Era, Pavia sprawled outside the Roman walls, creating new urban areas and modifying the landscape. Geomorphological and GIS-spatial analyses integrated with anthropic landform surveying, archaeological data and historical cartography were performed. This multi-disciplinary approach allowed an investigation into how urban development was firstly adapted and then superimposed onto fluvial landforms. As a result, a flexible geocultural itinerary is proposed for linking geoheritage with cultural heritage, and for disseminating urban geomorphology key-concepts.
Performance of rapid influenza H1N1 diagnostic tests: a meta-analysis: Accuracy of rapid H1N1 diagnostic tests
Creators: name: Chu, Haitao
name: Lofgren, Eric T.
name: Cole, Stephen R.
name: Kuan, Pei F.
name: Hudgens, Michael
name: Halloran, M. Elizabeth
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Following the outbreaks of 2009 pandemic H1N1 infection, rapid influenza diagnostic tests have been used to detect H1N1 infection. However, no meta-analysis has been undertaken to assess the diagnostic accuracy when this manuscript was drafted.
(3251) Theodore Reunert
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
[Descargar pdf] EL REY
Creators: name: Suarez
Publisher: name: Zenodo
Year: 2024

description: EL REY de JENNIFER L. ARMENTROUT

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EL REY

JENNIFER L. ARMENTROUT

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788419131454

Editorial: TITANIA

Año de edición: 2024

 

 

 

 

 

Descargar libros electrónicos de epub gratis para Android EL REY

 

Overview

Una historia en el universo deáCazadora de hadasEl Príncipe ahora es el Reyáy nada puede pararle.áPero Brightonáno sigue órdenes.Tras la proclamación de Caden como rey, Brighton Jussier haávuelto a la normalidad. No quiere que nada ni nadie se interpongaáentre ella y su venganza contra el asesino de su madre. Pero Cadenáno se lo pondrá nada fácil, ya que el desea lo mismo: acabar conáAric, el fae antiguo que le robó tantos años de vida.No pueden admitir sus sentimientos con todo lo que está enájuego, y, cuando el rey se ve en posición de elegir entre Brightonáy su corte, piensa que lo mejor para ambos es mantener las distancias.áPero todo cambia cuando Brighton cae en manos de Aric,áque planea utilizarla para que Caden le ayude a liberar a la reinaáde una vez por todas.Brighton sabe que rendirse no es una opción, pero cuando todaáesperanza parece desaparecer delante de sus ojos, ¿será suficienteásu voluntad para sobrevivir?
(3250) Mary Elizabeth Strutt
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Online Read Ebook Bridesmaid for Hire by Meghan Quinn
Creators: name: Douglas
Publisher: name: Zenodo
Year: 2024

description: Bridesmaid for Hire by Meghan Quinn

 

 

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Bridesmaid for Hire

Meghan Quinn

Page: 448

Format: pdf, ePub, mobi, fb2

ISBN: 9781728294360

Publisher: Sourcebooks

 

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Download it once and read it on your PC or mobile device PDF Bridesmaid for Hire by Meghan Quinn EPUB Download. EPUB Bridesmaid for Hire By Meghan Quinn PDF Download Share link here and get free ebooks to read online. Begin reading PDF Bridesmaid for Hire by Meghan Quinn EPUB Download plot. Uploaded fiction and nonfiction Bridesmaid for Hire EPUB PDF Download Read Meghan Quinn. eBook reading shares PDF Bridesmaid for Hire by Meghan Quinn EPUB Download free link for reading and reviewing PDF EPUB MOBI documents. New EPUB Bridesmaid for Hire By Meghan Quinn PDF Download - Downloading to Kindle - Download to iPad/iPhone/iOS or Download to B&N nook. Get it in epub, pdf , azw, mob, doc format. HQ EPUB/MOBI/KINDLE/PDF/Doc Read EPUB Bridesmaid for Hire By Meghan Quinn PDF Download ISBN. New eBook was published downloads zip PDF Bridesmaid for Hire by Meghan Quinn EPUB Download Audio Download, Unabridged. Rate this book PDF Bridesmaid for Hire by Meghan Quinn EPUB Download novels, fiction, non-fiction.

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Landform modifications within an intramontane urban landscape due to industrial activity, Wałbrzych, SW Poland
Creators: name: Jancewicz, Kacper
name: Traczyk, Andrzej
name: Migoń, Piotr
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: The city of Wałbrzych represents a geomorphic landscape, heavily modified by nearly three centuries of industrial activity, related mainly to coal mining. The key landforms due to human impact include spoil tips of various types, extensive levelled terrains, waste ponds, and railway embankments and cuts. Ground subsidence due to mining and water pumping have affected large areas. The map shows the distribution of anthropogenic landforms due to industrial activity, mainly coal mining, over an area of 85 km2. The thematic symbol set for the main map contains 22 classes of objects which show 13 distinctive types of landform modification due to construction, excavation, levelling and complex features. The Main Map is accompanied by inset maps showing generalized geology of the area, extent and magnitude of ground subsidence, as well as relief visualization.
Shape transition in the even-even Cerium isotopes
Creators: name: Mohammed-Azizi, B.
name: Helmaoui, A.
name: Medjadi, D. E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences
subject: J.2

description: The deformation energy of the even-even nuclei of the Cerium isotopic chain is investigated by means of the Macroscopic-Microscopic method with a semi-classical shell correction. We consider axially symmetric shapes. Binding energy and two neutron separation energy are also evaluated. For the sake of clarity several important details of the calculations are also given. It turns out that all these nuclei have prolate equilibrium shape. The regions of maximum deformation are obtained around N=64 and N=102. There is no critical-point of quantum phase transition in this isotopic chain.
description: 14 pages, 7 figures
Descargar EL ESTADO DE LA UNIÓN NICK HORNBY Gratis - EPUB, PDF y MOBI
Creators: name: Russell
Publisher: name: Zenodo
Year: 2024

description: EL ESTADO DE LA UNIÓN de NICK HORNBY

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EL ESTADO DE LA UNIÓN

NICK HORNBY

Número de páginas: 112

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788433918840

Editorial: ANAGRAMA

Año de edición: 2023

 

 

 

 

 

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Overview

Las punzantes conversaciones de un matrimonio en crisis. Nick Hornby escruta los conflictos de pareja con grandes dosis de ingenio.Cada semana, Tom y Louise tienen una cita en un pub londinense antes de su sesión de terapia de pareja. Su relación parecía ir bien hasta que un desliz generó grietas y afloraron las tensiones. Ahora están intentando reconducir la situación, en un intento de salvar un matrimonio de quince años que les ha dado dos hijos.La novela, organizada en diez capítulos, reproduce los diez minutos previos a diez sesiones de terapia. Durante ese tiempo Tom y Louise conversan y observan lo que sucede a su alrededor: la gente que entra en el pub, las parejas que salen de su sesión con la terapeuta antes de que pasen ellos…El motor de la narración son esas mismas conversaciones, cargadas de agudeza, ironía y sinceridad. Una suerte de terapia previa a la terapia, en la que la pareja protagonista repasa su vida en común y habla de todo: el pasado, sus diferencias y complicidades, el sexo y el amor, las expectativas y los desengaños, incluso el Brexit.Este libro ingenioso, incisivo y profundo bajo su apariencia de liviandad es la formulación literaria de la serie de televisión del mismo título, dirigida por Stephen Frears y protagonizada por Rosamund Pike y Chris O’Dowd, de la que Nick Hornby es guionista.