cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Measuring Coherent Elastic Neutrino Nucleus Scattering With The Cenns-10 Liquid Argon Detector
Creators: name: ZETTLEMOYER, Jacob
Publisher: name: Zenodo
Year: 2018

description: The COHERENT experiment recently made the first measurement of coherent elastic neutrino nucleus scattering (CEvNS) at the 6.7σ
\sigma
level with a 14.6 kg CsI(Na) crystal at the Oak Ridge National Laboratory. COHERENT uses the Spallation Neutron Source at ORNL as the neutrino source and also plans to test the N2
^2
dependence of the CEvNS cross section by making measurements on multiple targets. To that end, COHERENT also deploys a 22 kg fiducial mass liquid argon detector CENNS-10, which was commissioned at ORNL in late 2016. There have been two dedicated data runs of CENNS-10, one in early 2017 and one in late 2017 after an upgrade of the light collection ability and increased shielding. I will present initial results of the first data run, a first look at the second data run, and the future plans of the COHERENT liquid argon program.
The Difficulties in Measuring Individual Utilities of Product Attributes: A Choice Based Experiment
Creators: name: Meixner, Oliver
name: Haas, Rainer
Publisher: name: CentMa, Intern Center for Management, Communication, and Research
Year: 2017

description: The study combines different theoretical approaches in the field of conjoint analysis to estimate the im-portance of product related attributes. This is of major importance in food marketing, where we still try to find a valid answer, in particular, how to measure the real willingness to pay (WTP) for specific product specifica-tions. Based on a comprehensive literature analysis, a common method was used to approximate the im-portance of several product attributes. As usually suggested in literature, we used discrete choice modeling and developed a choice based experimental design considering selected product attributes. The study object was frozen pizza, a convenience good frequently bought by most households.
Up to this point, there is nothing special about the choice based experiment in comparison to direct measure-ment of the importance of product attributes. However, one of the core problems of discrete choice modeling – the approximation of individual utility functions – was then addressed by transforming the choices of con-sumers into scores. With these scores traditional conjoint measurement can be used to approximate individual utilities even in choice based experiments. The individual part-worth utilities will be compared with a usual but very complex approach to approximate individual part-worth utilities, the hierarchical Bayes method. Our ap-proach addresses methodological considerations concerning the restrictions of discrete choice modeling, namely the complexity of approximating individual utilities which is of huge importance in particular for market segmentation.
description: Proceedings in Food System Dynamics, Proceedings in System Dynamics and Innovation in Food Networks 2017
Racial Residential Segregation and Race Differences in Ideal Cardiovascular Health among Young Men
Creators: name: Thorpe, Roland J.
name: Baxter, Samuel L. K.
name: Frerichs, Leah
name: Weinberger, Morris
name: Chung, Richard
name: Skinner, Asheley C.
Publisher: name: MDPI
Year: 2021

description: BACKGROUND: Race disparities in cardiovascular disease (CVD) related morbidity and mortality are evident among men. While previous studies show health in young adulthood and racial residential segregation (RRS) are important factors for CVD risk, these factors have not been widely studied in male populations. We sought to examine race differences in ideal cardiovascular health (CVH) among young men (ages 24-34) and whether RRS influenced this association. METHODS: We used cross-sectional data from young men who participated in Wave IV (2008) of the National Longitudinal Survey of Adolescent to Adult Health (N = 5080). The dichotomous outcome, achieving ideal CVH, was defined as having ≥4 of the American Heart Association's Life's Simple 7 targets. Race (Black/White) and RRS (proportion of White residents in census tract) were the independent variables. Descriptive and multivariate analyses were conducted. RESULTS: Young Black men had lower odds of achieving ideal CVH (OR = 0.67, 95% CI = 0.49, 0.92) than young White men. However, RRS did not have a significant effect on race differences in ideal CVH until the proportion of White residents was ≥55%. CONCLUSIONS: Among young Black and White men, RRS is an important factor to consider when seeking to understand CVH and reduce future cardiovascular risk.
Food Losses in Supply Chains for Fruits, Vegetables and Potatoes between Field and Retail Shelf in North-Rhine Westphalia, Germany
Creators: name: Meyer, Christian
name: Frieling, Dominik
name: Hamer, Martin
name: Oertzen, Gero
Publisher: name: CentMa, Intern Center for Management, Communication, and Research
Year: 2017

description: Food losses occur for many reasons at all stages of supply chains for fruits, vegetables and potatoes. They cause immense economic, environmental and social costs – not only in developing countries but also in developed countries. According to the European Commission, about 90 million tonnes of food are wasted annually in Europe alone. However, particularly for the early stages of supply chains for fruits, vegetables and potatoes there is still a lack of reliable data. Thus, one objective of this study is to contribute to the quantification of food losses between field and retail, where the main focus is set on potatoes, apples, carrots, strawberries and asparagus. Furthermore, neither reasons why products are removed from the supply chains nor their alternative uses are fully examined yet. This is why, the study takes a look on those issues, too. Results are based on data from an online survey among producers of fruits, vegetables and potatoes in North-Rhine Westphalia, Germany and on interviews with producers and other supply chain experts. Findings suggest that the products’ size and form, their storage capabilities and food safety issues have big impacts on food losses. Despite a small sample size, these findings are in line with recent studies.
description: Proceedings in Food System Dynamics, Proceedings in System Dynamics and Innovation in Food Networks 2017
Biochemical characterization of MeCP2 in the brain
Creators: name: SCOTT STUART MAXWELL
Publisher: name: Monash University
Year: 2017
Subjects: subject: 60404 Epigenetics (incl. Genome Methylation and Epigenomics)
subject: FOS: Biological sciences

description: Our genomes contain a complete set of blueprints that instruct how each and every part of us is made. However, while the genome stores all this information, an additional level of management is required to ensure specific information is used at the correct time. These controlling or “epigenetic” factors include a protein called MeCP2. This thesis used various techniques to explore and gain greater understanding of MeCP2 function in the brain. Finally, we find new interactions of MeCP2 and highlight additional mechanisms of genome control that may be relevant to MeCP2 and its related neurological conditions.
Rates of Co-occurring Psychiatric Disorders in Autism Spectrum Disorder Using the Mini International Neuropsychiatric Interview
Creators: name: Lowery, Sarah C.
name: Greene, Rachel K.
name: Dichter, Gabriel S.
name: McWeeny, Sean
name: Mosner, Maya G.
name: Mazefsky, Carla A.
name: Shah, Jasmine S.
name: Kinard, Jessica L.
Publisher: name: Springer Nature
Year: 2019

description: Individuals with autism spectrum disorder (ASD) often meet criteria for at least one additional psychiatric disorder. The present study evaluated the utility of the Mini International Neuropsychiatric Interview (MINI) in assessing co-occurring psychiatric disorders in children, adolescents, and young adults with ASD. Ninety-one percent of children/adolescents and thirty-one percent of young adults were diagnosed with one or more co-occurring diagnoses using the MINI. MINI diagnostic rates were comparable to those found in the literature on children/adolescents with ASD; however, in young adults, MINI diagnostic rates were lower relative to rates found in the literature on young adults with ASD. Implications for treatment, transitioning to adulthood, and the need for instruments developed specifically to diagnose co-occurring disorders in ASD are discussed.
68350: Letter: To H.N. Howells.
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Describes arriving in France / assumptions about being put in the front lines immediately, but now in reserve trenches / glad that Howells has a weak heart, and is not in France / thoughts about death, wounding, neurasthenia (mental illness) / possible outcomes of surviving the war / mentions a Welsh colleague ('E. Kemp') who he may not see again, and who he spent time with / looking at the sky, thinking of poetry, and hearing machinegun fire in a communication trench / praises fellow soldiers / describes the look of the villages in France.
Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The "PRONE" study
Creators: name: Franzone, John
name: Friedman, Eugene
name: Castiblanco, Saramaria Afanador
name: Gupta, Ishaan
name: Ko, Emily R
name: Zaeh, Sandra
name: Zak, Martin
name: Damarla, Mahendra
name: Alavian, Naseem
name: Schwartz, Adam
name: Drummond, M Bradley
name: Punjabi, Naresh M
name: Suber, Tomeka
name: Linstrum, Kelsey
name: Bain, William
name: Corey, Kristin
name: Mock, Jason
Publisher: name: Elsevier
Year: 2021

description: While benefits of prone position in mechanically-ventilated patients have been well-described, a randomized-control trial to determine the effects of prone positioning in awake, spontaneously-breathing patients with an acute pneumonia has not been previously conducted. Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 PatiEnts: the "PRONE" Study (PRONE) was conducted in non-intubated hospitalized patients with coronavirus disease 2019 (COVID-19) pneumonia as defined by respiratory rate ≥ 20/min or an oxyhemoglobin saturation (SpO2) ≤ 93% without supplemental oxygen [1]. The PRONE trial was designed to investigate the effects of prone positioning on need for escalation in respiratory support, as defined by need for transition to a higher acuity level of care, increased fraction of inspired oxygen (FiO2), or the initiation of invasive mechanical ventilation. Secondary objectives were to assess the duration of effect of prone positioning on respiratory parameters such as respiratory rate and SpO2, as well as other outcomes such as time to discharge or transition in level of care.
A Mixed Methods Approach Towards Mapping and Economic Valuation of the Divici-Pojejena Wetland Ecosystem Services in Romania
Creators: name: Lamprinakis, L.
name: Rodriguez, D. G. P.
name: Prestvik, A. S.
name: Veidal, A.
name: Klimek, B.
Publisher: name: CentMa, Intern Center for Management, Communication, and Research
Year: 2017

description: Mapping and valuating ecosystem services has gained increasing attention over the last years and remains high in the research agenda. In this paper, a mixed methods approach is used to valuate ecosystem services provided by the Divici-Pojejena wetland in Romania. A qualitative part relied on focus group discussions and interviews to identify key stakeholders and the ecosystem services provided by the wetland site. The benefit transfer (BT) method was used for the monetary valuation of the identified ecosystem services that the wetland provides. Bird watching opportunities, water quality, and flood prevention services are among the highest valued services, while the amenity services are the least valued among all wetland services.
description: Proceedings in Food System Dynamics, Proceedings in System Dynamics and Innovation in Food Networks 2017
Quelles vitesses d’ajustement pour quels niveaux d’équilibre pour le taux d’intérêt interbancaire marocain ? Estimation et comparaison d’un modèle à réversion quadratique
Creators: name: HAMZAOUI, Moustapha
name: BOUSALAM, Issam
Publisher: name: Revue Economie, Gestion et Société
Year: 2015
Subjects: Processus SWING, Taux d’intérêt interbancaire marocain, LIBOR, EURIBOR, Méthode des moments généralisée (GMM).

description: Cet article a pour objet d’estimer les paramètres du modèle de retour à la moyenne (SWING à tendance aléatoire) appliqué au taux moyen pondéré interbancaire marocain et ses équivalents pour d’autres pays de comparaison (USA, Italie, Turquie et la Grèce). Nous cherchons à vérifier si les deux vitesses d’ajustement du processus vers l’équilibre sont différentes l’une de l’autre ou pas, et par la même occasion, déterminer les intervalles d’équilibres pour chacun des taux d’intérêt traités. Les résultats montrent que les deux vitesses de retour à l’équilibre (ascendante et descendante) pour tous les taux étudiés sont statistiquement différentes l’une de l’autre et il existe plusieurs intervalles d’équilibre dépendamment de celles-ci. Les résultats de la comparaison soulèvent également les différences structurelles des marchés de taux en comparaison et les comportements des acteurs y intervenant.
description: Revue Economie, Gestion et Société, No 2 (2015)
61042: Prizes awarded to Thomas Edgar Borrill at Rickett and Colman, Hull
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Copies from pages of 'Ours', the 'Reckitt Magazine', showing prizes awarded Thomas Edgar Borrill (1897-1917) before he joined the army.
Lance Corporal Thomas Edgar Borrill (1897-1917), service no. 30938, 2/8th Battalion, Sherwood Foresters (Notts & Derby Regt.)., service no. 30938, 2/8th Battalion, Sherwood Foresters (Notts & Derby Regt.).
Towards Automated Neutrino Selection At Microboone Using Tomographic Event Reconstruction
Creators: name: RUSSELL, Brooke
Publisher: name: Zenodo
Year: 2018

description: MicroBooNE is an approximately 90 metric ton single-phase liquid argon time projection chamber (LArTPC) and the first of a trio of LArTPCs in the Short Baseline Neutrino (SBN) program which will search for a light sterile neutrino and measure neutrino-argon interaction cross sections. Located in the Booster neutrino beam at Fermi National Accelerator Laboratory, MicroBooNE has taken neutrino data since October 2015. The near-surface operation of a LArTPC presents challenges in discriminating neutrino events from cosmic backgrounds. In this poster, we will describe the status of various technical components for selecting and analyzing neutrino-candidate events using Wire-Cell tomographic event reconstruction. In particular, we emphasize the interplay between scintillation light and ionization charge signals in identifying beam-spill coincident neutrino-candidate activity. Latest results will be shown.
Benchmarking Agri-Food Value Chain Performance Factors in South Mediterranean Countries
Creators: name: Mili, Samir
Publisher: name: CentMa, Intern Center for Management, Communication, and Research
Year: 2017

description: Fruits and vegetables (F&V) and olive oil are in South Mediterranean Countries (SMCs) two prominent agricultural activities in terms of contribution to national economy and exports. However, both are affected by inefficiencies and poor performance, in particular on the export market. In this paper we assess and compare performance factors between F&V and olive oil value chains (VCs) in Tunisia, Morocco, Egypt and Turkey, on the one side, and in Spain and Italy taken as benchmarks, on the other side. We propose an adapted Value Chain Maturity Model to benchmark performance factors in these VCs in SMCs. The proposed method could help to identifying poor performing areas in these VCs in order to suggest measures to improve their overall performance in general and export performance in particular. Findings confirm a robust association between VC maturity and performance. VC participants should learn from best practices and incorporate them for improvement, in particular in the areas of VC organization, responsiveness and technology adoption and implementation. In addition, more efficient agri-food exportation from SMCs needs more focus on trade facilitation issues including improvements in administrative procedures, infrastructure and technologies that reduce costs and time to export and facilitate investment. Further challenges outline the need for improvements in the areas of transparency, standards, certification, food safety, traceability and sustainability, taking into consideration that long-term partnerships are desired by international buyers to ensure product supply and quality. Public policies should be refocused towards these new challenges considering not only purely economic performance in these countries but also social development and environmental protection and resource preservation.
description: Proceedings in Food System Dynamics, Proceedings in System Dynamics and Innovation in Food Networks 2017
Regioselective Arene C-H Alkylation Enabled by Organic Photoredox Catalysis
Creators: name: Holmberg-Douglas, Natalie
name: Onuska, Nicholas P. R.
name: Nicewicz, David A.
Publisher: name: Wiley
Year: 2020

description: Expanding the toolbox of C-H functionalization reactions applicable to the late-stage modification of complex molecules is of interest in medicinal chemistry, wherein the preparation of structural variants of known pharmacophores is a key strategy for drug development. One manifold for the functionalization of aromatic molecules utilizes diazo compounds and a transition-metal catalyst to generate a metallocarbene species, which is capable of direct insertion into an aromatic C-H bond. However, these high-energy intermediates can often require directing groups or a large excess of substrate to achieve efficient and selective reactivity. Herein, we report that arene cation radicals generated by organic photoredox catalysis engage in formal C-H functionalization reactions with diazoacetate derivatives, furnishing sp2 -sp3 coupled products with moderate-to-good regioselectivity. In contrast to previous methods utilizing metallocarbene intermediates, this transformation does not proceed via a carbene intermediate, nor does it require the presence of a transition-metal catalyst.
An Assessment of the Food Companies Sustainability Policies through a Greenwashing Indicator
Creators: name: Zanasi, Cesare
name: Rota, Cosimo
name: Trerè, Simona
name: Falciatori, Sharon
Publisher: name: CentMa, Intern Center for Management, Communication, and Research
Year: 2017

description: There is an increasing interest in green marketing as a powerful tool to enhance the agrifood companies’ reputation and competitiveness; this makes it necessary to provide tools, for the consumers and the other stakeholders in the food system, able to detect the presence of distorted or false information often defined as greenwashing. It is also important for the agrifood companies to be able to prevent their communication to be unintentionally perceived as greenwashing, thus fully exploiting the value added provided by an effective communication of their sustainability policies.
The goal of this paper is to provide a monitoring tool able to support the food companies definition of effective green marketing strategies, avoiding the risk of greenwashing; moreover supporting the other food system stakeholders’ critical analysis of the sustainability communication coming from the food companies.
To this end a list of indicators coming from different organizations (Greenpeace, EnviroMedia Social Marketing and Oregon University, Terrachoice, Futerra) and authors (J.Grant, 2009) have been chosen and integrated in order to cover a broad range of sustainability dimensions and communication suggestions finalised to avoiding greenwashing in the agrifood sector.
The level of correctness and relevance of the companies communication as been assessed by measuring the number of actions described in the food companies’ Sustainability Report, falling within the indicators belonging to the different categories of green marketing and greenwashing.
The indicators have been tested on a large Italian food company: Barilla, by considering its Sustainability Report for the year 2016.
The results showed that the sustainability actions related to possible greenwashing represent a relatively low share of the total action implemented by Barilla. Most interesting is the capacity of this analytical tool to encompass a broad range of dimensions related to the companies green marketing strategies evaluation; this allows also other stakeholders to more clearly analyse the capacity of a company to provide a clear honest and complete report on their sustainability activities.
Further studies should weigh the different green marketing and greenwashing indicators in order to appreciate their relevance in contributing to the overall level of correct communication.
A sample of representative food chain stakeholders should be involved in providing an expert evaluation.
description: Proceedings in Food System Dynamics, Proceedings in System Dynamics and Innovation in Food Networks 2017
Regulation of large and small G proteins by ubiquitination
Creators: name: Campbell, Sharon L
name: Dohlman, Henrik G
Publisher: name: Elsevier
Year: 2019

description: Many sensory and chemical signal inputs are transmitted by intracellular GTP-binding (G) proteins. G proteins make up two major subfamilies: "large" G proteins comprising three subunits and "small" G proteins, such as the proto-oncogene product RAS, which contains a single subunit. Members of both subfamilies are regulated by post-translational modifications, including lipidation, proteolysis, and carboxyl methylation. Emerging studies have shown that these proteins are also modified by ubiquitination. Much of our current understanding of this post-translational modification comes from investigations of the large G-protein α subunit from yeast (Gpa1) and the three RAS isotypes in humans, NRAS, KRAS, and HRAS. Gα undergoes both mono- and polyubiquitination, and these modifications have distinct consequences for determining the sites and mechanisms of its degradation. Genetic and biochemical reconstitution studies have revealed the enzymes and binding partners required for addition and removal of ubiquitin, as well as the delivery and destruction of both the mono- and polyubiquitinated forms of the G protein. Complementary studies of RAS have identified multiple ubiquitination sites, each having distinct consequences for binding to regulatory proteins, shuttling to and from the plasma membrane, and degradation. Here, we review what is currently known about these two well-studied examples, Gpa1 and the human RAS proteins, that have revealed additional mechanisms of signal regulation and dysregulation relevant to human physiology. We also compare and contrast the effects of G-protein ubiquitination with other post-translational modifications of these proteins.
Additional file 2 of Nuclear lncRNA NORSF reduces E2 release in granulosa cells by sponging the endogenous small activating RNA miR-339
Creators: name: Wang, Miaomiao
name: Wang, Yang
name: Yang, Liu
name: Du, Xing
name: Li, Qifa
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Science Policy
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Hematology

description: Additional file 2: Fig. S1. The RNA expression profile of five DELs in sow follicular theca cells and GCs. Fig. S2. Heatmap of miR-144, miR-378, miR-339 and miR-375 signals in sow follicles and GCs. Fig. S3. Other two potential MREs of miR-339 in LOC102164325. Fig. S4. Identification of lncRNA NORSF. Fig. S5. NORSF negatively regulates CYP19A1 expression in GCs. Fig. S6. Percentage of lncRNA nucleoplasm in multiple human cell types. Fig. S7. Interaction networks of lncRNAs and miRNAs in the nucleus of multiple human cell types. Fig. S8. Nuclear lncRNAs MALAT1 and NEAT1 interact with multiple miRNAs in the nucleus of human GCs. Fig. S9. miR-339 mature sequences are highly conserved among vertebrates. Fig. S10. The MRE motifs of miR-339 in human LOC124906953.
Leveraging High Performance CIP Processes to Reduce Water Usage in the Beverage Industry
Creators: name: Weber, Curt M.
name: Roy, Sharon
Publisher: name: CentMa, Intern Center for Management, Communication, and Research
Year: 2017

description: The beverage industry around the world has been water-intensive, traditionally involving significant water usage, resulting in conflict over the viability of water sourcing vis-à-vis the respective surrounding ecosystems. Much of the usage has been related to the cleaning and sanitizing of manufacturing lines. With the advent of “clean-in-place” systems (CIP), it is possible to clean these lines in one minute in an environmentally friendly manner.
This article discusses the use of advanced CIP to improve the beverage production process through reduction of water consumption, and how continuous improvement will assist in solving a critical problem in food manufacture. The legal ramifications of treatment of water with a concentrated food cleaner will be discussed, as well as an investigation of attaining and exceeding established regulatory standards.
description: Proceedings in Food System Dynamics, Proceedings in System Dynamics and Innovation in Food Networks 2017
Relationship Between Central Artery Stiffness, Brain Arterial Dilation, and White Matter Hyperintensities in Older Adults: The ARIC Study-Brief Report
Creators: name: Palta, Priya
name: Tanaka, Hirofumi
name: Matsushita, Kunihiro
name: Qiao, Ye
name: Heiss, Gerardo
name: Wasserman, Bruce A.
name: Caughey, Melissa C.
name: Meyer, Michelle L.
Publisher: name: Wolters Kluwer
Year: 2021

description: Objective: Non-atherosclerotic outward remodeling of the large intracranial arteries may facilitate propagation of excessive aortic pulsatile energy into the cerebral microcirculation and has been associated with adverse cognitive outcomes. We sought to determine the relationship between central artery stiffness, brain arterial diameters, and white matter hyperintensity (WMH) volume in the general population of older adults. Approach and Results: We examined data from 1275 stroke-free participants of the Atherosclerosis Risk in Communities (ARIC) study (59% female, 30% Black, mean age 77 years) who underwent carotid-femoral pulse wave velocity (cf-PWV) testing and brain magnetic resonance imaging (MRI). A cf-PWV >12 m/s was considered elevated. Relationships between WMH and arterial diameters at the M1A1 segment of the middle and anterior cerebral arteries (whichever larger) were analyzed in the absence of artery-specific plaque, adjusting for intracranial volume and potential confounders. The average cf-PWV was 11.7 m/s and WMH volume was 11.2 cm3. Each 0.5 mm increment in M1A1 diameter was associated with 24% greater WMH volume in participants with elevated cf-PWV (exponentiated β = 1.24; 95% CI: 1.12 – 1.36), compared to a 10% greater WMH volume in participants without elevated cf-PWV (exponentiated β = 1.10; 95% CI: 1.01 – 1.19), P-interaction = 0.04. Conclusions: In this examination of older adults from the general population, larger, plaque-free arterial diameters in the middle cerebral circulation were associated with greater WMH volume, particularly among participants with elevated central artery stiffness. Strategies to reduce central artery stiffness may mitigate the association between cerebrovascular outward remodeling and microvascular damage.
Impasse budgétaire et incompressibilité des dépenses publiques au Maroc : Mise en Lumière d’un Rapport Critique
Creators: name: QACH, Nour-Eddine
Publisher: name: Revue Economie, Gestion et Société
Year: 2015
Subjects: Politique fiscale, politique budgétaire, dépenses publiques, conflit social.

description: Le présent essai entre en résonnance avec la situation de la crise fiscale et budgétaire traversant le Maroc où il est mis, en évidence, un monde économique et financier dominé plus par un conflit social se faisant vivement sentir en permanence, moins par la rationalité économique. Un monde où sont en lutte obstinée en effet, élus, administrateurs, groupes sociaux et lobbies (agricoles en particulier) ; pour faire triompher des visions divergentes, marchander ou décrocher des privilèges fiscaux ; et sur un autre plan, les politiques de réduction des dépenses publiques engendrent un douloureux destin social devant composer avec les stratégies des acteurs tant nationaux qu’internationaux.
description: Revue Economie, Gestion et Société, No 2 (2015)
Recent Progress On Wire-Cell Tomographic Event Reconstruction For Lartpcs
Creators: name: WEI, Hanyu
Publisher: name: Zenodo
Year: 2018

description: Event reconstruction is one of the most challenging tasks in analyzing the data from current and future massive liquid argon time projection chambers (LArTPCs) and its performance is critical to physics opportunities. MicroBooNE is an approximately 90 metric ton active volume single-phase LArTPC and the first of a trio of LArTPCs in the Short Baseline Neutrino (SBN) program which will search for a light sterile neutrino and measure neutrino-Argon interaction cross sections. A novel tomographic event reconstruction method, Wire-Cell, is under development and applied in MicroBooNE. In this poster, we will introduce the principle of Wire-Cell tomographic event reconstruction, which incorporates the time, charge, geometry, and sparsity information to reduce the ambiguity from wire readout. We will describe the challenges and realistic issues. The recent progress, including the latest 3D imaging results and the preliminary 3D clustering results, will be presented.
Simultaneous fMRI and fast-scan cyclic voltammetry bridges evoked oxygen and neurotransmitter dynamics across spatiotemporal scales
Creators: name: Shih, Yen-Yu Ian
name: Chao, Tzu-Hao Harry
name: Verber, Matthew
name: Lee, Sung-Ho
name: Walton, Lindsay R
name: Wightman, R Mark
Publisher: name: Elsevier
Year: 2021

description: The vascular contributions of neurotransmitters to the hemodynamic response are gaining more attention in neuroimaging studies, as many neurotransmitters are vasomodulatory. To date, well-established electrochemical techniques that detect neurotransmission in high magnetic field environments are limited. Here, we propose an experimental setting enabling simultaneous fast-scan cyclic voltammetry (FSCV) and blood oxygenation level-dependent functional magnetic imaging (BOLD fMRI) to measure both local tissue oxygen and dopamine responses, and global BOLD changes, respectively. By using MR-compatible materials and the proposed data acquisition schemes, FSCV detected physiological analyte concentrations with high temporal resolution and spatial specificity inside of a 9.4 T MRI bore. We found that tissue oxygen and BOLD correlate strongly, and brain regions that encode dopamine amplitude differences can be identified via modeling simultaneously acquired dopamine FSCV and BOLD fMRI time-courses. This technique provides complementary neurochemical and hemodynamic information and expands the scope of studying the influence of local neurotransmitter release over the entire brain.
Simultaneous recording of neuronal and vascular activity in the rodent brain using fiber-photometry
Creators: name: Shih, Yen-Yu Ian
name: Zhang, Wei-Ting
name: Chao, Tzu-Hao Harry
name: Cui, Guohong
Publisher: name: Elsevier
Year: 2022

description: Coupling of hemodynamic responses to neuronal activity is the foundation of several functional neuroimaging techniques. Here, we provide three fiber-photometry approaches to simultaneously measure neuronal and vascular signals in the rodent brain using a spectrometer-based system. Two out of these three approaches allow the removal of hemoglobin (Hb)-absorption artifacts and restore the underlying neuronal activity. This technique is applicable to different fluorescent sensors and provides a more accurate measurement of hemodynamic response function in any location of the rodent brain. For complete details on the use and execution of this protocol, please refer to Zhang et al. (2022).
Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree
Creators: name: Weaver, Valerie M
name: Giacometti, Simone
name: Fragiadakis, Gabriela K
name: Leonhardt, Laura
name: Lee, Jonghyun
name: Kim, Grace E
name: Hebrok, Matthias
name: Peng, Xianlu L
name: Rao, Arjun A
name: Li, Lucia Y
name: Smith, Jennifer A
name: Collisson, Eric A
name: Berrios, David I
name: Yeh, Jen Jen
name: Jiang, Honglin
name: Ashe, Sudipta
name: Hendley, Audrey M
name: Ye, Chun Jimmie
name: Pawlak, Mathias
name: Anderson, Mark S
Publisher: name: eLife
Year: 2021

description: To study disease development, an inventory of an organ's cell types and understanding of physiologic function is paramount. Here, we performed single-cell RNA-sequencing to examine heterogeneity of murine pancreatic duct cells, pancreatobiliary cells, and intrapancreatic bile duct cells. We describe an epithelial-mesenchymal transitory axis in our three pancreatic duct subpopulations and identify osteopontin as a regulator of this fate decision as well as human duct cell dedifferentiation. Our results further identify functional heterogeneity within pancreatic duct subpopulations by elucidating a role for geminin in accumulation of DNA damage in the setting of chronic pancreatitis. Our findings implicate diverse functional roles for subpopulations of pancreatic duct cells in maintenance of duct cell identity and disease progression and establish a comprehensive road map of murine pancreatic duct cell, pancreatobiliary cell, and intrapancreatic bile duct cell homeostasis.
Additional file 1 of Decentralized clinical trials and rare diseases: a Drug Information Association Innovative Design Scientific Working Group (DIA-IDSWG) perspective
Creators: name: Ghadessi, Mercedeh
name: Di, Junrui
name: Wang, Chenkun
name: Toyoizumi, Kiichiro
name: Shao, Nan
name: Mei, Chaoqun
name: Demanuele, Charmaine
name: Tang, Rui (Sammi)
name: McMillan, Gianna
name: Beckman, Robert A.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Biotechnology
Cancer
Science Policy
Mental Health

description: Supplementary Material
De l’interaction entre incitations pécuniaires et normes sociales : Une nouvelle explication des effets pervers des incitations
Creators: name: El MOUSSAOUI, Hicham
Publisher: name: Revue Economie, Gestion et Société
Year: 2015
Subjects: Incitations, normes sociales, motivation intrinsèque, approbation/désapprobation sociale, effet de substitution, effet de signal.

description: Dans l’économie standard des incitations, le Principal peut infléchir le comportement de l’Agent dans le sens désiré en mettant en place des règles de récompense ou de punition pécuniaire. Les incitations pécuniaires sont supposées – toutes choses égales par ailleurs - induire toujours les comportements désirés par le Principal. La validité de cette proposition est contestable à la fois sur le plan théorique et sur le plan empirique. Cet article cherche à expliquer pourquoi les incitations pécuniaires n’induisent pas l’effet escompté. Face à L’insuffisance de l’explication par l’éviction de la motivation intrinsèque, nous proposons une nouvelle explication dans la fonction expressive des (effets de signal) incitations employées et la manière dont le signal peut renforcer ou contredire la norme sociale. Nous démontrerons que l’effet final des incitations pécuniaires dépendra du rapport de force entre deux effets : l’effet de substitution (variation des prix relatifs des actions désirées et non désirées) et de l’effet de signal (variation de l’utilité lié à la variation de l’approbation ou désapprobation sociale).
description: Revue Economie, Gestion et Société, No 2 (2015)
61045: Special edition of the Reckitt & Sons company magazine 'Our's' recording the names of the fallen of the Great War
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Special edition of the Reckitt & Sons company magazine 'Our's' recording the names of the fallen of the Great War. This part of a collection that relates to T.E. Borrill whose name is recorded in the magazine.
Lance Corporal Thomas Edgar Borrill (1897-1917), service no. 30938, 2/8th Battalion, Sherwood Foresters (Notts & Derby Regt.).
Sliding window correlation analysis: Modulating window shape for dynamic brain connectivity in resting state
Creators: name: Laurienti, Paul J
name: Akhlaghi, Milad I
name: Wu, Guorong
name: Simpson, Sean L
name: Mokhtari, Fatemeh
Publisher: name: Elsevier
Year: 2019

description: The sliding window correlation (SWC) analysis is a straightforward and common approach for evaluating dynamic functional connectivity. Despite the fact that sliding window analyses have been long used, there are still considerable technical issues associated with the approach. A great effort has recently been dedicated to investigate the window setting effects on dynamic connectivity estimation. In this direction, tapered windows have been proposed to alleviate the effect of sudden changes associated with the edges of rectangular windows. Nevertheless, the majority of the windows exploited to estimate brain connectivity tend to suppress dynamic correlations, especially those with faster variations over time. Here, we introduced a window named modulated rectangular (mRect) to address the suppressing effect associated with the conventional windows. We provided a frequency domain analysis using simulated time series to investigate how sliding window analysis (using the regular window functions, e.g. rectangular and tapered windows) may lead to unwanted spectral modulations, and then we showed how this issue can be alleviated through the mRect window. Moreover, we created simulated dynamic network data with altering states over time using simulated fMRI time series, to examine the performance of different windows in tracking network states. We quantified the state identification rate of different window functions through the Jaccard index, and observed superior performance of the mRect window compared to the conventional window functions. Overall, the proposed window function provides an approach that improves SWC estimations, and thus the subsequent inferences and interpretations based on the connectivity network analyses.
Socioeconomic inequalities in early adulthood disrupt the immune transcriptomic landscape via upstream regulators
Creators: name: Harris, Kathleen Mullan
name: Ravi, Sudharshan
name: Cole, Steven W.
name: Levitt, Brandt
name: Shanahan, Michael J.
Publisher: name: Springer Nature
Year: 2024

description: Disparities in socio-economic status (SES) predict many immune system-related diseases, and previous research documents relationships between SES and the immune cell transcriptome. Drawing on a bioinformatically-informed network approach, we situate these findings in a broader molecular framework by examining the upstream regulators of SES-associated transcriptional alterations. Data come from the National Longitudinal Study of Adolescent to Adult Health (Add Health), a nationally representative sample of 4543 adults in the United States. Results reveal a network-of differentially expressed genes, transcription factors, and protein neighbors of transcription factors-that shows widespread SES-related dysregulation of the immune system. Mediational models suggest that body mass index (BMI) plays a key role in accounting for many of these associations. Overall, the results reveal the central role of upstream regulators in socioeconomic differences in the molecular basis of immunity, which propagate to increase risk of chronic health conditions in later-life.
Additional file 1 of Analgesic benefits of pre-operative versus postoperative transversus abdominis plane block for laparoscopic cholecystectomy: a frequentist network meta-analysis of randomized controlled trials
Creators: name: Dost, Burhan
name: De Cassai, Alessandro
name: Balzani, Eleonora
name: Geraldini, Federico
name: Tulgar, Serkan
name: Ahiskalioglu, Ali
name: Karapinar, Yunus Emre
name: Beldagli, Müzeyyen
name: Navalesi, Paolo
name: Kaya, Cengiz
Publisher: name: figshare
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health

description: Additional file 1: Supplementary material 1. Search Strategy.
Passenger Falls on Trams
Creators: name: Valenza, Luke
Publisher: name: Monash University
Year: 2020
Subjects: classificationCode: 330309
subject: Industrial and product design

description: The primary aim of this project is to identify the frequency, nature and contributing factors in relation to the incidence of falls on trams, which will provide an evidence base on which effective countermeasures can be developed to reduce the incidence and severity of falls and fall-related injuries on board trams.
แนวทางการพัฒนาและส่งเสริมการใช้จักรยานภายในมหาวิทยาลัยสีเขียว:มหาวิทยาลัยวลัยลักษณ์ จังหวัดนครศรีธรรมราช
Creators: name: นันท์นภัส เพชรคงทอง
Publisher: name: Thammasat Printing House
Year: 2017
Subjects: แนวทาง
โครงข่ายเส้นทางจักรยาน
จักรยาน
มหาวิทยาลัยสีเขียว

description: Journal of Architectural/Planning Research and Studies, 14, 2, 89-104
Socioeconomic inequalities in molecular risk for chronic diseases observed in young adulthood
Creators: name: Levitt, Brandt
name: Cole, Steven W.
name: Chumbley, Justin
name: Xu, Wenjia
name: Shanahan, Michael J.
name: Aiello, Allison
name: Ravi, Sudharshan
name: Bodelet, Julien
name: Gaydosh, Lauren
name: Harris, Kathleen Mullan
name: Potente, Cecilia
Publisher: name: Proceedings of the National Academy of Sciences
Year: 2022

description: Many common chronic diseases of aging are negatively associated with socioeconomic status (SES). This study examines whether inequalities can already be observed in the molecular underpinnings of such diseases in the 30s, before many of them become prevalent. Data come from the National Longitudinal Study of Adolescent to Adult Health (Add Health), a large, nationally representative sample of US subjects who were followed for over two decades beginning in adolescence. We now have transcriptomic data (mRNA-seq) from a random subset of 4,543 of these young adults. SES in the household-of-origin and in young adulthood were examined as covariates of a priori-defined mRNA-based disease signatures and of specific gene transcripts identified de novo. An SES composite from young adulthood predicted many disease signatures, as did income and subjective status. Analyses highlighted SES-based inequalities in immune, inflammatory, ribosomal, and metabolic pathways, several of which play central roles in senescence. Many genes are also involved in transcription, translation, and diverse signaling mechanisms. Average causal-mediated effect models suggest that body mass index plays a key role in accounting for these relationships. Overall, the results reveal inequalities in molecular risk factors for chronic diseases often decades before diagnoses and suggest future directions for social signal transduction models that trace how social circumstances regulate the human genome.
Satellite data of Shanghai in 2015
Creators: name: Zhang, Hui
Publisher: name: Zenodo
Year: 2024

description: Name:S2B_MSIL2A_20241103T023759_N0511_R089_T51RUQ_20241103T043219.SAFE

 

Size:1099MB

 

Sensing time:2024-11-03T02:37:59.024000Z

 

Platform short name:SENTINEL-2

 

Instrument short name: MS

 

product ID:https://zipper.dataspace.copernicus.eu/odata/v1/Products(69b871c5-a915-46d7-a8d8-79ba5e70be76)/$value
Space wandering in the rodent default mode network
Creators: name: Branigan, Nicholas K.
name: Lee, Byeongwook
name: Nghiem, Trang-Anh Estelle
name: Mistry, Percy K.
name: Chao, Tzu-Hao Harry
name: Shih, Yen-Yu Ian
name: Menon, Vinod
Publisher: name: Proceedings of the National Academy of Sciences
Year: 2024

description: The default mode network (DMN) is a large-scale brain network known to be suppressed during a wide range of cognitive tasks. However, our comprehension of its role in naturalistic and unconstrained behaviors has remained elusive because most research on the DMN has been conducted within the restrictive confines of MRI scanners. Here, we use multisite GCaMP (a genetically encoded calcium indicator) fiber photometry with simultaneous videography to probe DMN function in awake, freely exploring rats. We examined neural dynamics in three core DMN nodes-the retrosplenial cortex, cingulate cortex, and prelimbic cortex-as well as the anterior insula node of the salience network, and their association with the rats' spatial exploration behaviors. We found that DMN nodes displayed a hierarchical functional organization during spatial exploration, characterized by stronger coupling with each other than with the anterior insula. Crucially, these DMN nodes encoded the kinematics of spatial exploration, including linear and angular velocity. Additionally, we identified latent brain states that encoded distinct patterns of time-varying exploration behaviors and found that higher linear velocity was associated with enhanced DMN activity, heightened synchronization among DMN nodes, and increased anticorrelation between the DMN and anterior insula. Our findings highlight the involvement of the DMN in collectively and dynamically encoding spatial exploration in a real-world setting. Our findings challenge the notion that the DMN is primarily a "task-negative" network disengaged from the external world. By illuminating the DMN's role in naturalistic behaviors, our study underscores the importance of investigating brain network function in ecologically valid contexts.
QARAQALPAQSTANDAǴI KOREYC DIASPORASI
Creators: name: Sharjaubayeva, Gúlpira
Publisher: name: Zenodo
Year: 2024

description: Házirgi kúnde milletler ara tatıwlıq, tuwsıqan xalıqlar arasındaǵı    mádeniy  qatnasıqlar hám baylanislar haqqında tereńırek úyreniw. Bul maqala mámleketshiligimizde turizim tarawin rawajlandiriwda qońsı etnomádeniyatlardı úyreniw.
Additional file 2 of Analgesic benefits of pre-operative versus postoperative transversus abdominis plane block for laparoscopic cholecystectomy: a frequentist network meta-analysis of randomized controlled trials
Creators: name: Dost, Burhan
name: De Cassai, Alessandro
name: Balzani, Eleonora
name: Geraldini, Federico
name: Tulgar, Serkan
name: Ahiskalioglu, Ali
name: Karapinar, Yunus Emre
name: Beldagli, Müzeyyen
name: Navalesi, Paolo
name: Kaya, Cengiz
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health

description: Additional file 2: Supplementary material 2. Funnel Plots.