Initial analysis of archived non-human primate frontal and rear impact data from the biodynamics data resource
Creators: name: Ardyn V. Olszko
name: Beltran, Christine M.
name: Vasquez, Kimberly B.
name: McGhee, James S.
name: Valeta C. Chancey
name: Yoganandan, Narayan
name: Pintar, Frank A.
name: Baisden, Jamie L.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences
subject: FOS: Biological sciences

description: <b>Objective</b>: The research objective was to conduct an initial analysis of non-human primate (NHP) data from frontal and rear impact events archived in the Biodynamics Data Resource (BDR) records of the Naval Biodynamics Laboratory (NBDL). These rare data, collected between 1973 and 1989, will inform the safety community of upper-end tolerance limits of NHP and may be related to severe crash scenarios. <b>Methods</b>: Data from frontal and rear acceleration tests to 93 macaque NHP were examined. Each NHP was fully torso restrained, whereas the head–neck complex was unrestrained. Each NHP underwent between 1 and 21 total runs; 2 total runs was most common—a low-level run and then a high-level run. Following each impact exposure, the NHP was evaluated using a series of medical examinations. Now part of the legacy collection in the BDR, these evaluations were used to assess NHP exposures to be in one of 3 categories: noninjurious, injurious, or fatal. Using reported peak sled acceleration values, data were amenable to survival analysis statistical methodology to derive injury probability curves (IPCs). IPCs were derived for injury and fatality outcomes. <b>Results</b>: Fatal injuries for both frontal and rear impacts were mostly at the cranio-vertebral junction. In addition to hemorrhage, fatal frontal and rear impact tests both produced predominantly atlanto-occipital dislocations, with and without spinal cord transection. After exclusions, IPCs were derived for frontal and rear impact for both (1) fatal outcome and (2) injurious outcome (any injury including fatal injury). For frontal impact, 53 NHP qualified with 5, 25, and 50% risk for fatality at 89, 105, and 114 peak sled <i>G</i>s, respectively, and for injurious outcome at 70, 92, and 106 <i>G</i>s, respectively. For rear impact, 34 NHP qualified with 5, 25, and 50% risk for fatality at 96, 122, 138 peak sled <i>G</i>s, respectively, and for injurious outcome at 75, 99, and 115 <i>G</i>s, respectively. <b>Conclusions</b>: The majority of injuries were at the cranio-vertebral junction, indicating that the inertial head mass caused a tensile loading mechanism to the cervical spine. These data may be used in conjunction with finite element modeling to estimate risks to the human population. The most direct application in the automotive environment could be to the well-restrained child. The <i>N<sub>ij</sub></i> neck injury criteria, currently based on data from piglet studies, could also benefit because the NHP is a more accurate human surrogate. These types of tests are likely to never be repeated and will form an upper bound of tolerance information valuable to safety system designers.