cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Indicadores para el diseño de recursos multimedia
Creators: name: Ernesto Paz Enrique, Luis
name: Hernández Alfonso, Eduardo Alejandro
name: Tunal Santiago, Gerardo
Publisher: name: unknown
Year: 2020
Subjects: subject: Interactive multimedia

description: La divulgación, evaluación y descripción de la ciencia ha sido un aspecto esencial en la sociedad moderna. Los resultados de investigación en los países del llamado Tercer Mundo se caracterizan por su escaza socialización y mínima absorción significativa en los educandos o pares académicos. Se plantea como objetivo del estudio: establecer indicadores para el diseño de recursos multimedia. La investigación clasifica como descriptiva con aporte teórico. En este sentido, las representaciones multimedia favorecen que los resultados de investigación se difundan con mayor impacto, a través de los actuales recursos tecnológicos. Los indicadores contienen las fases imprescindibles para el diseño de presentaciones multimedia que faciliten la socialización del conocimiento, y no derive en lo que se conoce como ciencia perdida.
Indicadores para el diseño de recursos multimedia
Creators: name: Ernesto Paz Enrique, Luis
name: Hernández Alfonso, Eduardo Alejandro
name: Tunal Santiago, Gerardo
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Interactive multimedia

description: La divulgación, evaluación y descripción de la ciencia ha sido un aspecto esencial en la sociedad moderna. Los resultados de investigación en los países del llamado Tercer Mundo se caracterizan por su escaza socialización y mínima absorción significativa en los educandos o pares académicos. Se plantea como objetivo del estudio: establecer indicadores para el diseño de recursos multimedia. La investigación clasifica como descriptiva con aporte teórico. En este sentido, las representaciones multimedia favorecen que los resultados de investigación se difundan con mayor impacto, a través de los actuales recursos tecnológicos. Los indicadores contienen las fases imprescindibles para el diseño de presentaciones multimedia que faciliten la socialización del conocimiento, y no derive en lo que se conoce como ciencia perdida.
Real-world psoriasis treatment patterns and disease burden in Germany, with a focus on biologics and apremilast: data from a German statutory health insurance database
Creators: name: Pinter, Andreas
name: Schulte, Marcus
name: Kossack, Nils
name: Pignot, Marc
name: Schultze, Michael
name: Feldhus, Andrea
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Psoriasis is a chronic, systemic, inflammatory skin disease, with increasing prevalence; however, few studies have reported real-world prescription patterns and healthcare burden. This retrospective, observational cohort study used statutory health insurance claims data (January 2014–December 2019) to estimate prevalence/incidence of moderate-to-severe psoriasis in Germany. Patient characteristics, treatment patterns/compliance, and healthcare resource utilization (HCRU)/costs were evaluated, focusing on apremilast and anti-interleukin (IL), and anti-tumor necrosis factor (TNF) biologics. The epidemiology population included adults with psoriasis; 1-year prevalence/incidence rates were extrapolated to the statutory health insurance population. The HCRU/costs population included adults with psoriasis and a first prescription for a drug of interest (index date). Baseline periods were 12 or 48 months before the index date, with 12‑month follow-up. In 2019, the estimated psoriasis prevalence/incidence was 2,672.9 per 100,000 individuals/508.7 per 100,000 person-years. Of 2,809 patients in the HCRU/costs population, 3.6% (n = 101) received index drug apremilast, 10.2% (n = 287) anti-IL, 6.8% (n = 191) anti-TNF, and 79.4% (n = 2,230) traditional/other systemic therapy. Patients initiating apremilast were older and were more often biologic-naïve than those initiating anti-IL/TNF biologics. Twelve months after treatment initiation, drug adherence (medication possession rate >80%) and persistence (<60 days between prescriptions/no switch) were lower for apremilast vs. anti-IL and anti-TNF groups (24.8% vs. 59.6% and 53.9%; 36.6% vs. 66.9% and 57.6%, respectively). During a 12-month baseline period, psoriasis-related hospitalization was lower for apremilast vs. anti-IL and anti-TNF groups (4.95% vs. 15.68% and 14.14%) and higher during 12 months’ follow-up (5.94% vs. 2.44% and 3.14%). Adjusted index drug costs during follow-up were €4,105, €3,498, and €13,777 higher for adalimumab, other anti-TNF and anti-IL biologics vs. apremilast, respectively, and the main driver for lower overall apremilast costs. Given variation in treatment adherence/persistence, HCRU, and costs between apremilast and biologics, these findings could be key considerations during treatment selection.
Estándares para el diseño visual e informacional de aplicaciones móviles
Creators: name: Canto Hernández, Lauren Reyis
name: Ernesto Paz Enrique, Luis
name: Hernández Alfonso, Eduardo Alejandro
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Information services

description: El desarrollo tecnológico tiene entre sus principales ejemplos la tecnología móvil. Es por ello que, en la última década se incrementó el uso de aplicaciones para dispositivos móviles. Se identifica una presencia considerable de desarrolladores de aplicaciones móviles, con la finalidad de aumentar la visibilidad de sus diseños realizados en función de las necesidades del usuario. Se plantearon como objetivos del estudio: 1) Determinar aspectos teórico - conceptuales acerca del surgimiento y desarrollo del diseño visual e informacional para aplicaciones móviles y 2) Identificar los estándares usados para el diseño visual e informacional para aplicaciones móviles. Para la obtención de los resultados se emplearon métodos en los niveles teóricos y empíricos. Se utilizó como técnica la revisión de documentos para identificar los estándares más empleados en la producción científica publicada al respecto. Se establecieron generalidades sobre los estándares para el diseño visual e informacional de las aplicaciones móviles. Los estándares para el diseño visual e informacional establecidos constituyen una guía para el trabajo de los profesionales e instituciones encargadas del diseño de una aplicación móvil.
A Swedish cost-utility analysis of ferric derisomaltose versus ferric carboxymaltose in the treatment of iron deficiency anemia in patients with inflammatory bowel disease
Creators: name: Lindgren, Stefan C
name: Strid, Hans
name: Hjortswang, Henrik
name: Manxhuka, Bardh
name: Nanu, Neesha
name: Pollock, Richard F.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Iron deficiency anemia (IDA) is a common extraintestinal manifestation of inflammatory bowel disease (IBD), driven by impaired iron absorption, inflammation of intestinal mucosa and blood loss due to intestinal bleeding. Exogenous iron is indicated to correct iron deficiency, with intravenous iron preferred in patients with malabsorption or intolerance of oral iron, active bleeding, systemic inflammation, or a need for rapid iron replenishment. The objective was to assess the cost-utility of two high-dose, rapid-infusion iron formulations — ferric derisomaltose (FDI) and ferric carboxymaltose (FCM) — in the treatment of patients with IBD and IDA in Sweden. The analysis used a previously-published micro-simulation model. Phosphate monitoring was modeled based on the product labelling, while iron need and disease-related quality of life (QoL) were modeled based on data from the PHOSPHARE-IBD randomized controlled trial. Cost-utility was evaluated from the national healthcare payer perspective over a five-year time horizon. Sensitivity and scenario analyses were performed. For each iron treatment course, patients treated with FDI required 0.41 fewer infusions than those treated with FCM. The reduced number of infusions resulted in savings of SEK 9,876 over five years from iron administration costs alone (SEK 44,216 with FCM versus SEK 34,340 with FDI). Phosphate monitoring in patients treated with FCM cost SEK 2,776 over five years versus no monitoring costs with FDI. Total cost savings with FDI were SEK 14,962. FDI also resulted in a 0.076 quality-adjusted life year (QALY) improvement versus FCM driven primarily by the QoL improvements reported in PHOSPHARE-IBD, and FDI was therefore the dominant intervention. The analysis did not capture costs or outcomes associated with hypophosphatemic osteomalacia or fractures. Relative to FCM, fewer infusions of FDI were required, there was no need for phosphate monitoring, and disease-related QoL was improved, while overall costs were reduced.
Fuzzy Minimal and Maximal δ-Open Sets
Creators: name: D. R., Kirubaharan
name: S, Joseph
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Fuzzy logic
subject: Fuzzy mathematics
subject: Fuzzy sets

description: The aim of this article is to introduce fuzzy minimal δ-open and fuzzy maximal δ-open sets in fuzzy topological space. Further, we investigate some properties with these new sets.
Fuzzy Paraopen Sets and Maps in Fuzzy Topological Spaces
Creators: name: A, Swaminathan
name: R, Balakumar
name: S, Joseph
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Fuzzy sets
subject: Fuzzy mathematics
subject: Fuzzy numbers
subject: Fuzzy topology

description: The purpose of this article is to study the concepts of fuzzy para open and fuzzy para closet sets in fuzzy topological spaces Further, we introduce a few classes of fuzzy maps namely fuzzy part continuous, fuzzy part continuous, fuzzy para irresolute, fuzzy minimal part continuous, fuzzy maximal part continuous mappings and study their properties.
Stanisław Karłowski (1879-1939): Pioneer of Biodynamic Farming and Organic Agriculture in Poland
Creators: name: Bietkowski, Pawel
name: Paull, John
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Organic farming
subject: Biodynamic agriculture
subject: Anthroposophy
subject: Anthroposophists
subject: Sustainable development
subject: Sustainable agriculture
subject: Agriculture
subject: Poland
subject: Bankers
subject: Extrajudicial executions

description: Stanisław Karłowski (1879-1939) was one of the great champions of Biodynamic farming during its formative years. After an illustrious career as an international banker, in 1920 he purchased the Szelejewo Estate in Poland comprising 1,724 hectares. Rudolf Steiner (1861-1925) presented his Agriculture Course at Koberwitz (now Kobierzyce, Poland) in the summer of 1924. Rudolf Steiner called for farming to be based on natural and biological principles and the farm to be considered as an organism. Steiner's seminal course laid the grounds for the subsequent development of Biodynamic and organic farming. Karłowski encountered Biodynamics in 1929. He converted his Szelejewo Estate to Biodynamics, thereby creating what was, at the time, likely the largest Biodynamic (BD) farm in Europe, and perhaps the world (c.f. Ehrenfried Pfeiffer’s farm, Loverendale, Netherlands, was 320 hectares). Karłowski published a series of seven booklets (in Polish) promoting the practice of Biodynamics (including a translation of Ehrenfried Pfeiffer); these are believed to be the first Biodynamics publications in Polish. Stanisław Karłowski ran courses on Biodynamics at his Estate and made the BD preparations available. He implemented Rudolf Steiner’s injunction to test the ideas of the Agriculture Course and he published his results and observations in ‘Demeter’. Karłowski was a member of Rudolf Steiner’s ‘Experimental Circle of Anthroposophic Farmers and Gardeners’, the ‘inner sanctum’ of those pioneering the development of Biodynamics in its gestational years of the turbulent interwar period.  He brought to the task an economic viewpoint, the attention to detail of a banker, and the independence of thought of a non-Anthroposophist. Within weeks of the German invasion of Poland, Karłowski was executed by a Nazi firing squad in the town square of Gostyń, his wife was deported, his beloved Szelejewo Estate was appropriated by the Nazis, and Poland was extinguished as a sovereign state.
Additional file 1 of Prioritization of pig farm biosecurity for control of Salmonella and hepatitis E virus infections: results of a European expert opinion elicitation
Creators: name: Galipó, Erika
name: Zoche-Golob, Veit
name: Sassu, Elena Lucia
name: Prigge, Christopher
name: Sjölund, Marie
name: Tobias, Tijs
name: Rzeżutka, Artur
name: Smith, Richard Piers
name: Burow, Elke
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1. Table S1. Number of invited experts and number of respondents kept in the analysis, by country. Table S2. Summary of the frequency of setting combination as selected in the 46 responses from experts that were kept in the analysis. Table S3. Participants’ self-assessed knowledge ranking in each of the five domains: on indoor farming systems, outdoor farming systems, Salmonella spp., HEV and on-farm biosecurity. Tables S4-S7. All biosecurity categories and all individual biosecurity measures included in the questionnaire and applied to the control of Salmonella spp. and HEV in indoor and outdoor farming, ranked by relevance and agreement. Figure S1. Distribution of all participants to the survey in the self-assessed knowledge ranks in percentages.
Systemic sclerosis presenting TAFRO syndrome-like manifestations including renal glomerular microangiopathy: a case report and literature review
Creators: name: Kawahara, Hiroyuki
name: Hara, Satoshi
name: Iwaki, Noriko
name: Ikeda, Hiroko
name: Inoue, Dai
name: Mizushima, Ichiro
name: Nomura, Hideki
name: Masaki, Yasufumi
name: Iwata, Yasunori
name: Kawano, Mitsuhiro
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Virology
subject: Computational Biology

description: TAFRO syndrome is a systemic inflammatory disorder of unknown etiology, and its diagnosis requires the exclusion of autoimmune diseases. A 42-year-old Japanese woman presented with TAFRO syndrome-like manifestations, but had undiagnosed limited-cutaneous systemic sclerosis preventing a definitive diagnosis of TAFRO syndrome. However, her clinical course and pathological findings, including renal glomerular microangiopathy, were consistent with TAFRO syndrome. We performed a systematic review of the literature to evaluate how autoimmunity affects the clinical characteristics of TAFRO syndrome/idiopathic multicentric Castleman disease (iMCD)-TAFRO. We reviewed 95 reported cases of TAFRO syndrome/iMCD-TAFRO and found that at least 41 (43.6%) had various autoantibodies. In particular, the positive rates of anti-nuclear antibody, anti-SS-A antibody, anti-SS-B antibody, PA-IgG, and direct Coombs test were high. Furthermore, we identified 14 cases of autoimmune diseases with TAFRO syndrome-like manifestations. We compared the clinical characteristics of these 14 with those of the autoantibody-positive and -negative cases among the 95 cases of TAFRO syndrome/iMCD-TAFRO. Apart from sex ratio, we found no significant difference in clinical presentation, treatment, or outcome among the groups. In conclusion, TAFRO syndrome/iMCD-TAFRO often accompanies autoantibodies and shares many clinical characteristics with other autoimmune diseases. Clinicians should be aware that some autoimmune diseases mimic TAFRO syndrome/iMCD-TAFRO.
title: Технологический процесс механической обработки детали «втулка»
title: бакалаврская работа
titleType: Subtitle
Creators: name: Яцков, Илья Александрович
Publisher: name: Unknown
Year: 2016
Subjects: технологический процесс
операционная наладка
базирование

description: В бакалаврской работе разработан технологический процесс на механическую обработку детали втулка, изготовленной из Стали 45 ГОСТ 1050-88. Наружная поверхность - ступенчатая. Дана характеристика конструктивной и технологической особенности детали. Произведен выбор метода получения заготовки, последовательность обработки, технологическое оборудование,  обеспечивающие минимальную трудоемкость и себестоимость изготавливаемой детали при достижении заданного качества. Исходя из этого, рассчитаны припуски и режимы резания с нормированием операций для условий серийного производства. Разработана конструкция приспособления для обработки детали. В дипломном проекте выполнен анализ существующего технологического процесса механической обработки втулки и выявлены его недостатки. Спроектирован технологический процесс с использованием вертикально-фрезерных, горизонтально-фрезерных, вертикально-сверлильных и токарно-винторезных станков. Сконструировано контрольно-измерительное приспособление.
Gloomy Divergence: Death/Doom Metal as Dark Leisure
Creators: name: Yavuz, M.Selim
Publisher: name: unknown
Year: 2016
Subjects: subject: Culture
subject: Musical analysis
subject: Musicology
subject: Heavy metal (Music)--Instruction and study
subject: Popular music
subject: Music--Sociological aspects

description: Death doom metal or death/doom emerges as a distinct style in early 1990s mostly focused in northern England. This style or, tentatively, sub-genre of doom may be argued to be a leisure space for participants in this culture. Dark leisure theory attempts to describe non-mainstream leisure activity, and even though it started in criminological and psychological approaches under moral absolutism relying heavily on deviancy and social control; with recent scholars such as Karl Spracklen, DJ Williams and Philip Stone and their work, this area is on its way to become a more fruitful perspective, especially in relation to extreme music subcultures. The presentation will introduce death doom metal style under the light of dark leisure through music and culture.
The religious struggle framework: Religious experience from struggle to transformation
Creators: name: Amali Aminnuddin, Nur
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Islam
subject: Muslims
subject: Experience (Religion)
subject: Struggle
subject: Social psychology
subject: Self-actualization (Psychology)
subject: Individual differences
subject: Individual differences--Religious aspects--Islam
subject: Positive psychology
subject: Counseling

description: The phenomenon of young individuals struggling with their religious beliefs can lead to wide-ranging consequences. Existing studies are dominantly Western in context, which may not be applicable in other settings. Therefore, as contextualized and rationalized through an Islamic perspective, the present study aims to build a framework to explore religious struggle. Through a qualitative research design, multiple methods were employed: responses from six Muslim interviewees were reconstructed into a single monologue using the composite narrative method, and then narrative analysis was done, followed by method theory and domain theory analyses being conducted. Constructs were identified and discussed, theories as lenses to view the phenomenon were employed, and further evaluations of the phenomenon and relevant constructs were done. A discussion was integrated with each analysis. Through synthesizing the findings, I propose a framework called the religious struggle framework (RSF). With the RSF’s flexible, adaptable, and modifiable nature, the framework can be used beyond the present study’s population. It can be utilized in both quantitative and qualitative research designs. Limitations and recommendations for further research were also presented.
Additional file 2 of Comparing pedigree and genomic inbreeding coefficients, and inbreeding depression of reproductive traits in Japanese Black cattle
Creators: name: Nishio, Motohide
name: Inoue, Keiichi
name: Ogawa, Shinichiro
name: Ichinoseki, Kasumi
name: Arakawa, Aisaku
name: Fukuzawa, Yo
name: Okamura, Toshihiro
name: Kobayashi, Eiji
name: Taniguchi, Masaaki
name: Oe, Mika
name: Ishii, Kazuo
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Figure S2. Scatter plot of ROH-based chromosomal inbreeding coefficients
All-cause healthcare resource utilization and costs among community-managed adults with long-COVID in France, 2020–2023
Creators: name: Yang, Jingyan
name: Cheikh Tamberou
name: Arnee, Elise
name: Squara, Pierre-Alexandre
name: Boukhlal, Ayoub
name: Nguyen, Jennifer L.
name: Volkman, Hannah R.
name: Fiévez, Stéphane
name: Lepoutre-Bourguet, Marina
name: Ren, Jinma
name: Romdhane, Haifa Ben
name: Crépey, Pascal
name: Robineau, Olivier
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The clinical and economic burden of long COVID is poorly understood. We aim to assess all-cause healthcare resource utilization (HCRU) and costs in the primary care setting among adults with long COVID in France. A retrospective cohort study using the electronic healthcare records (EHRs) of confirmed and/or probable COVID-19 patients from The Health Improvement Network (THIN) data between March 2020 and December 2022 was conducted. Long COVID was identified per World Health Organization (WHO) definition as suggestive symptoms present ≥3 months following acute SARS-CoV-2 infection. Patients’ characteristics, HCRU, direct healthcare and indirect costs (National Health Insurance-based prices) were summarized. Costs between patients with previous SARS-CoV-2 infection who developed long COVID, patients with previous SARS-CoV-2 infection who did not develop long COVID (COVID only), and contemporaneous controls without SARS-CoV-2 infection were compared (Non-COVID). Long COVID developed among 30,122 (11.6%) adults; mean (SD) age was 50 (17) years, 63.6% were female and 27.5% had a Charlson Comorbidity Index score >2. During the post-infection follow-up (mean = 13 months), 97.3% of patients had general practitioner consultations (GP) and 62.4% had nursing care. Costs were highest during the first post-diagnosis year with per patient per year costs of €2,443 (total cost of €52 million), including costs for GP (€208) and specialist (€170) consultations, outpatient procedures (€413), retail pharmacy use (€595), biological testing (€147), and medical device usage (€172). Patients with long COVID had additional costs of €163 and €176 when compared to patients in the COVID only and Non-COVID cohorts, respectively. Since the THIN database is generated from GP EHRs, there is the possibility of measurement/documentation errors and missing values which could compromise the validity and accuracy of certain results. Long COVID was associated with non-negligible HCRU, direct and indirect costs to the French healthcare system. These findings reinforce the importance of optimizing long-term resource allocation for patients infected with SARS-CoV-2.
Additional file 3 of Comparing pedigree and genomic inbreeding coefficients, and inbreeding depression of reproductive traits in Japanese Black cattle
Creators: name: Nishio, Motohide
name: Inoue, Keiichi
name: Ogawa, Shinichiro
name: Ichinoseki, Kasumi
name: Arakawa, Aisaku
name: Fukuzawa, Yo
name: Okamura, Toshihiro
name: Kobayashi, Eiji
name: Taniguchi, Masaaki
name: Oe, Mika
name: Ishii, Kazuo
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Figure S3. Trend lines of ROH-based inbreeding coefficients in chromosomes 2, 14, 19 and 22 which were associated with age at first calving at birth years from 1998 to 2020
Religiousness differences and associations of beliefs and practices: Muslims in religious and non-religious work environments
Creators: name: Amali Aminnuddin, Nur
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Islam
subject: Muslims--Ethnic identity
subject: Individual differences--Religious aspects
subject: Individual differences--Religious aspects--Islam
subject: Work environment
subject: Brunei
subject: Religiousness
subject: Faith
subject: Islam--Customs and practices
subject: Muslims

description: This study addressed the following four questions: Does the influence of Islam is highly prevalent in the life of Malay Muslims in Brunei? Is the level of religiousness high? Are their religious beliefs associated with their religious practices? Are there any differences in religiousness between employees in religious work environment (RWE) and non-religious work environment (NRWE)? Using responses from 370 Malay Muslim employees, several measures of religiousness were analyzed. Analyses were done to determine descriptive statistics, correlations, and group differences. Findings showed that the influence of Islam was highly prevalent at all levels. They reported influence of Islam not only at personal level, but also at both upbringing and organizational levels. Religiousness was high, while beliefs and practices were interrelated. Malay Muslim employees in RWE were observed to have higher Islamic religiousness relative to those in NRWE. These findings highlight that in a theistic society where religiousness is already high, the nature of work environment can still potentially play a role in making a difference.
Cost-effectiveness and public health impact of using high dose influenza vaccine in the Japanese older adults
Creators: name: de Courville, Caroline
name: Tadera, Chiho
name: Arashiro, Takeshi
name: Bianic, Florence
name: Costa, Mafalda
name: Joshi, Mohit
name: Wang, Xinyu
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: High-dose (HD) influenza vaccine, which has demonstrated superior efficacy and acceptable safety compared to standard-dose (SD), has market authorization in many countries. This study evaluated the public-health impact and cost-effectiveness of HD versus SD in Japanese older-adults (OAs) from healthcare payer-perspective. Decision-tree model was employed assessing health outcomes for each vaccination strategy, simulating influenza cases, outpatient/emergency department (ED) visits, hospitalizations, and mortality, over one-year time-horizon. Incremental cost-effectiveness ratios (ICER) were assessed at Japanese willingness-to-pay (WTP) threshold. Base-case analysis considered influenza vaccines effective against influenza hospitalizations only, whereas complementary analyses reflected their efficacies against Pneumonia and Influenza (P&I), respiratory and cardiorespiratory hospitalizations possibly related to influenza among individuals ≥65 years. Scenario analysis extended target population to at-risk individuals aged 60–64 years. Uncertainty was assessed using sensitivity analyses. In base-case, switching from SD to HD prevented 174,863 influenza cases, 121,084 outpatient and 614 ED visits, annually. Further, 5,777 influenza hospitalizations, and 2,406 deaths related to influenza were avoided with HD vaccine. The HD vaccine was found to be a cost-effective strategy at WTP threshold of ¥5,000,000/Quality-Adjusted-Life-Years (QALY) with ICER of ¥4,876,512/(QALY). Sensitivity analyses confirmed the robustness of these findings. Complementary analyses showed notably improved outcomes, in terms of public-health, economic impact, and ICERs, when considering efficacy of influenza vaccines against P&I, respiratory, and cardiorespiratory hospitalizations possibly related to influenza. These results indicate that HD vaccine has a high economic value in Japan compared to SD. Implementing HD vaccine could effectively alleviate the burden on healthcare facilities for Japanese OAs.
Women of Colour: Using Corpus Analysis for Introducing Representations of Race in Nineteenth-Century Fiction
Creators: name: Norman, Annelise
name: Stecher, Gabrielle
Publisher: name: unknown
Year: 2021

description: As a digital humanities tool, corpus analysis allows students to visually map language use. Adopted as a tool for anti-racist pedagogy, corpus analysis allows us to recognize from a distance the role race plays in a given text, visualizing its prominences, patterns, and even silences. Because the tools used in corpus analysis strip context and subjectivity from these texts, the following activity allows students to think about documents from a distance. Presented with decontextualized language, students can predict how the texts engage with and represent matters of race. In making their predictions, students may uncover biases and assumptions about race, historical periods, and narrative voice that require further investigation.
Women of Colour: Using Corpus Analysis for Introducing Representations of Race in Nineteenth-Century Fiction
Creators: name: Norman, Annelise
name: Stecher, Gabrielle
Publisher: name: Humanities Commons
Year: 2021

description: As a digital humanities tool, corpus analysis allows students to visually map language use. Adopted as a tool for anti-racist pedagogy, corpus analysis allows us to recognize from a distance the role race plays in a given text, visualizing its prominences, patterns, and even silences. Because the tools used in corpus analysis strip context and subjectivity from these texts, the following activity allows students to think about documents from a distance. Presented with decontextualized language, students can predict how the texts engage with and represent matters of race. In making their predictions, students may uncover biases and assumptions about race, historical periods, and narrative voice that require further investigation.
D5.1 AgriBIT community platform (rev. 1)
Creators: name: Scrima, Piero
name: Vella, Giuseppe
Publisher: name: Zenodo
Year: 2021

description: The objective of this document is to explain how to use the AgriBIT Community Platform and to describe its components and functionalities. The document, in the first section (1 Introduction), introduces the platform providing information on its context and an overview of its functionalities.The second section (2 The platform technologies stack) deals with the technological stack, describing the subsystems of the platform, their role and showing an example of executive flow between the subsystems.

The content structure of the platform is the subject of the third section (3 Content structure). In the first part (3.1 General) covers the analysis of the common elements of the pages, such as menus, search bars and data structure. The next part of the third section is the subchapter that deals with the OpenAPI (OpenAPI GUI), it starts with an overview of the OpenAPI1 standard and then address the description of the structure and the components of the user interface provided by the APIs pages of the platform. The section ends explaining how users can execute an API request by means this user interface. The topics of the rest of chapter encompasses the contents of the different sections and pages of the platform. The document ends with the conclusions that highlight the function of this document in this phase of the project.
Additional file 3 of Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study
Creators: name: Yao, Chongjie
name: Zhang, Yuchen
name: Lu, Ping
name: Xiao, Bin
name: Sun, Pingping
name: Tao, Jiming
name: Cheng, Yanbin
name: Kong, Lingjun
name: Xu, Dongsheng
name: Fang, Min
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Additional file 3: Supplementary file 3. MR results of localized pain on risk of sleeplessness/insomnia, anxiety/panic attacks and depression with scatter plots.
Real-world perioperative treatment patterns and economic burden of recurrence in early-stage HER2-negative breast cancer: a SEER-Medicare study
Creators: name: Earla, Jagadeswara Rao
name: Kponee-Shovein, Kalé
name: Kurian, Allison W.
name: Mahendran, Malena
name: Song, Yan
name: Hua, Qi
name: Hilts, Annalise
name: Sun, Yezhou
name: Hirshfield, Kim M.
name: Mejia, Jaime A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: This study aimed to describe treatment patterns and quantify the economic impact of recurrence in early-stage human epidermal growth factor receptor 2 (HER2)-negative breast cancer (BC). Medicare beneficiaries with stages I–III HER2-negative BC and lumpectomy or partial/total mastectomy were identified from SEER-Medicare data (2010–2019). Perioperative therapies were reported in the neoadjuvant and adjuvant setting. Locoregional recurrence and distant metastasis were identified using a claims-based algorithm developed with clinical input and consisting of a diagnosis-based and treatment-based indicator. All-cause and BC-related healthcare resource utilization (HRU) per-patient-month and monthly healthcare costs were estimated from the recurrence date for patients with recurrence and from an imputed index date for patients without recurrence using frequency matching. HRU and costs were compared between groups stratified by hormone receptor-positive (HR+) or triple negative BC (TNBC) using multivariable regression models. Of 28,655 patients, 8.5% experienced recurrence, 90.4% had HR+ disease, and 5.6% received neoadjuvant therapy. Relative to patients without recurrence, patients with recurrence had more advanced disease (stage II/III: 73.7% vs. 34.0%) and higher-grade tumors (Grade 3/4: 40.6% vs. 18.0%) at diagnosis. Recurrence in HR+/HER2-negative BC and TNBC was associated with higher rates of all-cause hospitalizations (incidence rate ratio [IRR]: 2.84 and 3.65), emergency department (ED) visits (IRR: 1.75 and 2.00), and outpatient visits (IRR: 1.46 and 1.55; all p < 0.001). Similarly, recurrence was associated with higher rates of BC-related HRU, particularly for ED visits in HR+/HER2-negative BC (IRR: 4.24; p < 0.001) and hospitalizations in TNBC (IRR: 11.71; p < 0.001). Patients with HR+/HER2-negative BC and TNBC recurrence incurred higher monthly all-cause (cost difference [CD]: $3988 and $4651) and BC-related healthcare costs (CD: $3743 and $5819). Our findings highlight the considerable economic burden of recurrence in early-stage HER2-negative BC and underscore the unmet need for optimization of therapies that reduce recurrence in this population.
Properties and antibacterial effectiveness of metal-ion doped borate-based bioactive glasses
Creators: name: Fakher, Sarah
name: Westenberg, David
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Space Science
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology

description: Bioactive glasses (BGs) are physiologically reactive surface biomaterials widely used in biomedical applications and various treatments. Borate bioactive glasses (BBGs) are third-generation BGs, and they exhibit superior biodegradable, bioactive, osteoconductive, antibacterial, and biocompatible properties compared to other types of BGs. Certain concentrations of dopant ions can be incorporated into the chemical structure of BBGs to enhance their biological functionalities and antimicrobial properties. It was demonstrated that those ions play a crucial role in the biological responsiveness in vitro and in vivo once in contact with a physiological environment. The dissolution products of ion-doped BBGs were noted in their ability to stimulate gene expression related to cell differentiation and proliferation, promote angiogenesis, display anti-inflammatory effects, and inhibit bacterial growth within a few hours. Thus, metal-ion-doped BBGs address several limitations encountered by biomedical, tissue engineering, and infection control applications. Considering the research studies on BBGs to date, this review aims to analyze metal-ion-doped BBGs based on their primary antibacterial properties and effectiveness. This paper explores borate bioactive glasses (BBGs), innovative materials designed to help heal wounds, repair body tissues and fight infections. These glasses break down quickly in the body and turn into a substance that bonds well with bones, making them ideal for medical applications. By adding tiny amounts of metals like copper, silver, or zinc, these glasses gain powerful properties which can stop harmful bacteria from growing and forming protective layers that are hard to treat. BBGs can be used in many ways, such as coatings for implants, dressings for wounds and carriers for antibiotics. They have shown great success in clinical trials for healing chronic wounds and preventing infections, especially in hospital settings. While these materials hold exciting promise for improving healthcare, more research is needed to fully understand how they work and ensure they are safe and effective for different uses.
बहुजन साहित्य प्रगतिशील और दलित साहित्य का विस्तार है: प्रमोद रंजन
Creators: name: Ranjan, Pramod
Publisher: name: unknown
Year: 2022
Subjects: subject: Literary movements
subject: Criticism
subject: Hindi literature--Dalit authors
subject: Dalits in literature
subject: Progressivism in literature
subject: Hindi literature
subject: Caste in literature

description: -आज समाचार सेवा, पटना-
*बहुजन साहित्य प्रगतिशील और दलित साहित्य का विस्तार है*
*प्रमोद रंजन से बातचीत*

प्रश्न: आपने बहुजन साहित्य की अवधारणा पर भी काम किया है। इस अवधारणा के बारे में कुछ बताएं।

प्रमोद रंजन: बहुजन साहित्य का अर्थ है– अभिजन के विपरीत बहुजन का साहित्य और उनकी वैचारिकी। प्रगतिशील- मार्क्सवादी विचारधारा में जो 'जन' है, 'बहुजन' उसकी अगली कड़ी भी है। मार्क्सवाद के 'जन' का अर्थ भारत के सामाजिक-यथार्थ के संदर्भ में न सिर्फ अस्पष्ट और अनिश्‍चित बना रहता है, बल्कि वह हमारे सांस्कृतिक मंतव्यों को प्रकट नहीं करता। जब हम 'जन' में 'बहु' प्रत्यय जोड़ते हैं तो इससे बना शब्द हिंदुस्तानी परिप्रेक्ष्य में वैचारिक और दार्शनिक रूप से भी जीवंत बन उठता है। यह हमें भारत की श्रमणवादी धारा के दार्शनिकों, कौत्स, बुद्ध, मक्खली गोशाल, अजित केशकंबली आदि की वैज्ञानिक चेतना से जोड़ देता है और उनके दर्शन को समकालीन आवश्यकता के अनुरूप विकसित करने के लिए प्रेरित करता है। "बहुजन" में बहुलता का भाव है। नए भाषा संकेतों का सहारा लेकर कहें तो यह जन + (जन प्लस) भी है। जन+ के अर्थ में यह पिछले दो दशक से पश्चिम में चर्चित हो रही उत्तर-मानववाद जैसी धारणााओं को तार्किक दिशा देने में भी सक्षम है। कहना प्रगतिशील साहित्य में वंचित तबकों के दु:खों का चित्रण तो हुआ, लेकिन वह उन दाहक दु:खों के कारण के रूप में ब्राह्मणवाद को चिन्हित में सक्षम नहीं था। दलित साहित्य को दु:ख देने वाला भी दिखा, उसने उन दु:खों के कारणों को गहराई से रेखांकित किया। बहुजन साहित्य की अवधारणा से दु:ख भी दिखता है, दु:ख देने वाला भी दिखता है, और दुख से मुक्ति का उपाय भी दिखता है।
Cost-effectiveness of a machine learning risk prediction model (LungFlag) in the selection of high-risk individuals for non-small cell lung cancer screening in Spain
Creators: name: Trujillo, Juan Carlos
name: Soriano, Joan B.
name: Marzo, Mercè
name: Higuera, Oliver
name: Gorospe, Luis
name: Pajares, Virginia
name: Olmedo, María Eugenia
name: Arrabal, Natalia
name: Flores, Andrés
name: García, José Francisco
name: Crespo, María
name: Carcedo, David
name: Heuser, Carolina
name: Obradović, Milan M. S.
name: Olghi, Nicolò
name: Choman, Eran N.
name: Seijo, Luis M.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: The LungFlag risk prediction model uses individualized clinical variables to identify individuals at high-risk of non-small cell lung cancer (NSCLC) for screening with low-dose computed tomography (LDCT). This study evaluates the cost-effectiveness of LungFlag implementation in the Spanish setting for the identification of individuals at high-risk of NSCLC. A model combining a decision-tree with a Markov model was adapted to the Spanish setting to calculate health outcomes and costs over a lifetime horizon, comparing two hypothetical scenarios: screening with LungFlag versus non-screening, and screening with LungFlag versus screening the entire population meeting 2013 US Preventive Services Task Force (USPSTF) criteria. Model inputs were obtained from the literature and the clinical practice of a multidisciplinary expert panel. Only direct costs (€of 2023), obtained from local sources, were considered. Deterministic and probabilistic sensitivity analyses were performed to assess the robustness of our results. A cohort of 3,835,128 individuals meeting 2013 USPSTF criteria would require 2,147,672 LDCTs scans. However, using LungFlag would only require 232,120 LDCTs scans. Cost-effectiveness results showed that LungFlag was dominant versus non-screening scenario, and outperformed the scenario where the entire population were screened since the observed loss of effectiveness (-224,031 life years [LYs] and −97,612 quality-adjusted life years [QALYs]) was largely offset by the significant cost savings provided (€7,053 million). The resulting incremental cost-effectiveness ratio (ICER) for this strategy of screening the whole population versus using LungFlag was €72,000/QALY, showing that LungFlag is cost-effective. Various were described, such as the source of the efficacy or adherence rates, and other limitations inherent to cost-effectiveness analyses. Using LungFlag for the selection of high-risk individuals for NSCLC screening in Spain would be a cost-effective strategy over screening the entire population meeting USPSTF 2013 criteria and is dominant over non-screening.
Additional file 6 of Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study
Creators: name: Yao, Chongjie
name: Zhang, Yuchen
name: Lu, Ping
name: Xiao, Bin
name: Sun, Pingping
name: Tao, Jiming
name: Cheng, Yanbin
name: Kong, Lingjun
name: Xu, Dongsheng
name: Fang, Min
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Additional file 6: Supplementary file 6. Results of Leave-one-out analysis.
बहुजन साहित्य प्रगतिशील और दलित साहित्य का विस्तार है: प्रमोद रंजन
Creators: name: Ranjan, Pramod
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Hindi literature
subject: Criticism
subject: Caste in literature
subject: Literary movements
subject: Hindi literature--Dalit authors
subject: Dalits in literature
subject: Progressivism in literature

description: -आज समाचार सेवा, पटना- *बहुजन साहित्य प्रगतिशील और दलित साहित्य का विस्तार है* *प्रमोद रंजन से बातचीत*  प्रश्न: आपने बहुजन साहित्य की अवधारणा पर भी काम किया है। इस अवधारणा के बारे में कुछ बताएं।  प्रमोद रंजन: बहुजन साहित्य का अर्थ है– अभिजन के विपरीत बहुजन का साहित्य और उनकी वैचारिकी। प्रगतिशील- मार्क्सवादी विचारधारा में जो ‘जन’ है, ‘बहुजन’ उसकी अगली कड़ी भी है। मार्क्सवाद के ‘जन’ का अर्थ भारत के सामाजिक-यथार्थ के संदर्भ में न सिर्फ अस्पष्ट और अनिश्‍चित बना रहता है, बल्कि वह हमारे सांस्कृतिक मंतव्यों को प्रकट नहीं करता। जब हम ‘जन’ में ‘बहु’ प्रत्यय जोड़ते हैं तो इससे बना शब्द हिंदुस्तानी परिप्रेक्ष्य में वैचारिक और दार्शनिक रूप से भी जीवंत बन उठता है। यह हमें भारत की श्रमणवादी धारा के दार्शनिकों, कौत्स, बुद्ध, मक्खली गोशाल, अजित केशकंबली आदि की वैज्ञानिक चेतना से जोड़ देता है और उनके दर्शन को समकालीन आवश्यकता के अनुरूप विकसित  करने के लिए प्रेरित करता है। “बहुजन” में बहुलता का भाव है। नए भाषा संकेतों का सहारा लेकर कहें तो यह जन + (जन प्लस) भी है। जन+ के अर्थ में यह  पिछले दो दशक से पश्चिम में चर्चित हो रही उत्तर-मानववाद जैसी धारणााओं को तार्किक दिशा देने में भी सक्षम है। कहना प्रगतिशील साहित्य में वंचित तबकों के दु:खों का चित्रण तो हुआ, लेकिन वह उन दाहक दु:खों के कारण के रूप में ब्राह्मणवाद को चिन्हित में सक्षम नहीं था। दलित साहित्य को दु:ख देने वाला भी दिखा, उसने उन दु:खों के कारणों को गहराई से रेखांकित किया। बहुजन साहित्य की अवधारणा से दु:ख भी दिखता है, दु:ख देने वाला भी दिखता है, और दुख से मुक्ति का उपाय भी दिखता है।
Open access and closed discourses: Constructing open access as a development issue.
Creators: name: Haider, Jutta
Publisher: name: unknown
Year: 2008
Subjects: subject: Library science
subject: Information science
subject: Postcolonialism

description: This thesis investigates the connection between open access – the free online availability and distribution of scientific and scholarly publications – and the 'developing world' from a post- development perspective. It takes a discourse analytical approach, drawing predominantly on Michel Foucault's understanding of discourse and on postdevelopment studies and theory. It aims to answer the following questions: - Which notions of science, of development and progress, of knowledge as well as of information and technology are capitalised on in the open access debates and in which way are they shaped as a consequence? - Which discursive effects can be established, what are the results and of which kind are they?
MPEC 2025-F36 : 2025 FV
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 FV

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Creation, God, and the Coronavirus
Creators: name: Brett, Mark
name: Goroncy, Jason
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Theology, Doctrinal
subject: Creation
subject: Theodicy
subject: Bible

description: This short reflection argues that, in the face of natural crises that occur in the world, responsible Christian speech requires a much fuller and more thickly textured understanding of creation than is often presented. Reading the Bible leads us to avoid speculating on the origins or purposes of such crises. Rather, it bears witness to the divine promise of hope in the healing justice of God, and calls human persons and human communities to participate in that justice through responsible action.