cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
1-hydroxy-6,6-Dimethyl-3-Phenyl-1,6-Dihydropyridine-2,5-Dione as a Promising Inhibitor of the SARS-CoV-2 Proteins: insight into the Crystal Structure, Hirshfeld Surface Analysis and Computational Study
Creators: name: Babashkina, Maria G.
name: Taskin-Tok, Tugba
name: Burkhanova, Tatyana M.
name: Safin, Damir A.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: In this work detailed studies of 1-hydroxy-6,6-dimethyl-3-phenyl-1,6-dihydropyridine-2,5-dione (1), which is of potential biological interest, are reported. The molecule of 1 is stabilized by O–H···O and two C–H···O hydrogen bonds. The former interaction yields a pseudo-aromatic hydrogen bonded five-membered ring. The overall crystal packing of 1 is mainly described by O–H···O hydrogen bonds and π···π interactions, yielding a 1D supramolecular ribbon-like chain. These chains are linked through weak C–H···O hydrogen bonds. The reciprocal favored intermolecular H···H/C/O and C···C contacts are main contributors to the total Hirshfeld surface of 1. The structure, electronic and optical properties of 1 were verified with the DFT calculations, which revealed that 1 is a strong electrophile with the most pronounced nucleophilic and electrophilic centers located on the carbonyl oxygen atoms and on the hydroxyl hydrogen atom, respectively. Values for the calculated polarizability and first-order hyperpolarizability parameters for a molecule of 1 are higher in comparison to those of urea. Bioavailability, druggability as well as absorption, distribution, metabolism, excretion and toxicity properties of 1 were evaluated using the SwissADME, BOILED-Egg and ProTox-II tools. It was established that for 1, the human blood-brain barrier penetration property is positive and gastrointestinal absorption property is high with the negative PGP effect on the molecule. Molecular docking was applied to examine the influence of this compound on a series of the SARS-CoV-2 proteins, of which 1 exhibits the best affinity behavior toward RdRp-RNA, nonstructural protein 14 (N7-MTase) and N protein (NCB site).
Marital Quality and Depressive Symptoms among Older Hispanic Adults in the United States
Creators: name: Nazario-Acevedo, Jaminette M.
name: Yamashita, Takashi
name: Bulanda, Jennifer Roebuck
name: Brown, J. Scott
Publisher: name: Oxford University Press
Year: 2024

description: Objectives Despite the cultural importance of marriage as a social support system and its well-established link to mental health, older Hispanic adult populations, which are the largest racial and ethnic minoritized groups, remain understudied. The current study examined how positive and negative dimensions of marital quality are associated with depressive symptoms. Methods Data from Hispanic adults aged 51 years and older (n = 1,012) were obtained from the 2016 and 2018 Health and Retirement Study (HRS) waves. The CES-D scale (0-8 symptoms) was modeled as a function of positive and negative marital quality measures (1-4), as well as the relevant covariates. Results Results from a negative binomial regression model showed that a one-unit change in positive and negative marital quality was associated with a 23.61% reduction and a 23.74% increase, respectively, in depressive symptoms. The interaction terms with marital quality and gender, as well as marital quality and religion, were not statistically significant. Discussion In the U.S., a large percentage of older Hispanic adults are immigrants, and their extended family tends to reside in their countries of origin. As such, older Hispanic adults may have smaller social networks, and marital quality most likely represents a culturally important social support network in later life. Significant associations between depressive symptoms and marital quality among older Hispanic adults should receive more attention in family and public health policy discussions, particularly given the increasing diversity in U.S. society.
title: Multiculturalism, Identities and National Uncertainties in Southwest Europe: The Rise of Xenophobia and Populism in Catalonia (Spain)
Creators: name: Clua I Fainé, Montserrat
Publisher: name: University of Massachusetts Amherst
Year: 2012
Subjects: subject: Social and Cultural Anthropology

description: The analysis of the discourses about the migratory threat takes a special feature in the Catalan case, where there is an historical strong nationalist movement that seeks to defend its own Catalan national and cultural identity against Spain. A nationalist discourse that has been self-defined as a "civic nationalism" because it claims that has historically receipted and integrated the different peoples that have arrived at its territory. But it has showed in some moments a clear xenophobic discourse against immigration, especially during the 60s and 70s, against the massive arrival of Spanish migrants that was produced at that time in Catalonia (Clua 2011). Now it seems that it reappears in public sphere, to achieve political representation at last local elections (22/5/2011). I refer mainly to the rise of PxC (Platform for Catalonia, a xenophobic far-right party) but I also refer to some candidates for mayor that are members of the PP (Popular Party, a moderate conservative party that has won recent national elections in Spain). These candidates have used a discourse of rejection to the immigration (and the problems of crime and insecurity that this supposedly implied) to win elections in cities as Badalona. But the thesis of the paper is that, before the public presence of this populist discourse against immigration (or behind or underneath), there is evidence of previous exclusion actions, that were already incubating racist discourses in towns and cities of Catalonia with a significant immigrant presence.
The use of social media to gather qualitative data: A case of government E-procurement implementation and use
Creators: name: Nurdin, Nurdin
name: Stockdale, Rosemary
name: Scheepers, Helana
Publisher: name: Swinburne
Year: 2024

description: The emergence of social media is enabling researchers to consider new data collection and triangulation strategies. Quantitative researchers have taken advantage of the emergence of the Internet as a medium to gather data. Meanwhile, interpretive researchers are only now being able to harness the potential that social media provide in generating more insight into collected data. Using a case of government e-procurement implementation and use in an Indonesian regency, we illustrate how social media exchange, postings, and conversations can be used as a source of rich qualitative data to enhance understanding of a topic being studied. Our findings show that monitoring social media exchange, postings, and conversation can strengthen our understanding and interpretation of offline data (such as interviews). This study contributes to literature on the use of online media for interpretive data collection.
Fabrication and Characterization of Copper (II) Complex Supported on Magnetic Nanoparticles as a Green and Efficient Nanomagnetic Catalyst for Synthesis of Diaryl Sulfones
Creators: name: Abdelbasset, Walid Kamal
name: Mohsen, Ahmed M.
name: Kadhim, Mustafa M.
name: Alkaim, Ayad F.
name: Mustafa, Yasser Fakri
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified

description: A novel magnetically recoverable copper catalyst was successfully fabricated through the immobilization of Cu(OAc)2 on the surface of silica-coated magnetic Fe3O4 nanoparticles (Fe3O4@SiO2) functionalized with amine and thiol groups as ligand. The as-fabricated Fe3O4@SiO2-Imine/Thio-Cu(II) nanocomposite was fully characterized by FT-IR spectroscopy, SEM, EDX, TEM, XRD, VSM, ASS and ICP-OES techniques. The Fe3O4@SiO2-Imine/Thio-Cu(II) nanocomposite exhibited high catalytic activity in the synthesis of biologically active diaryl sulfones. According to our research on the literature, this is the first report in the use of magnetic copper nanocatalyst for the synthesis of diaryl sulfones via sulfonylative Suzuki–Miyaura cross-coupling reactions. This method gives notable advantages such as easy separation of the catalyst by external magnetic field; excellent yields, short reaction times, nontoxic metal catalyst, and simplicity of operation make this method a facile tool for the synthesis of diaryl sulfones.
How can effective governance build business opportunities between australia and the visegrád countries?
Creators: name: Perenyi, Aron
name: Esposto, Alexis
Publisher: name: Swinburne
Year: 2024

description: Australia’s economic ties to Europe relatively weakened over the past decades, the Asian Century opened up new opportunities, and diverted attention from a Euro-centric political and economic view. This paper does not challenge the merit of Australia’s current global orientation. However, it does take the opportunity to a possibility for diversification, using effective leadership in raising business opportunities with the emerging region of Europe: the Visegrád Countries. This group of nations have been earmarked as the best performing, latest additions to the EU. Outcomes of a round table discussion with key stakeholders of the Australia – Central Europe business relations are documented and cross-referenced with extant literature to highlight the main areas in which effective leadership can build business opportunities.
Biotreatment of Chlorpyrifos in a Bench Scale Bioreactor using Psychrobacter Alimentarius T14
Creators: name: Saira Khalid
name: Hashmi, Imran
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Microbiology
subject: FOS: Biological sciences
subject: Engineering
subject: Biochemistry

description: Bacteria tolerant to high pesticide concentration could be used for designing an efficient treatment technology. Bacterial strains T14 was isolated from pesticide contaminated soil in mineral salt medium (MSM) and identified as Psychrobacter alimentarius T14 using 16S rRNA gene sequence analysis. Bench scale bioreactor was evaluated for biotreatment of high Chlorpyrifos (CP) concentration using P. alimentarius T14. Effect of various parameters on bioreactor performance was examined and optimum removal was observed at optical density (OD600nm) 0.8, pH; 7.2, CP concentration; 300 mg L-1 and hydraulic retention time (HRT) 48h. At optimum conditions 70.3/79% of CP/COD removal was achieved in batch bioreactors. In addition P. alimentarius T14 achieved 95/91, 62.3/75, 69.8/64% CP/COD removal efficiency with addition of CS (co-substrates), CS1 (yeast extract + synthetic wastewater), CS2 (glucose + synthetic wastewater) and CS3 (yeast extract) respectively. Addition of CS1 to bioreactor could accelerate CP removal rate upto many cycles with considerable efficiency. However accumulation of 3, 5, 6-trichloro-2-pyridinol(TCP) affects reactor performance in cyclic mode. First order rate constant k1 0.062 h-1 and t1/2 11.1 h demonstrates fast degradation. Change in concentration of total chlorine and nitrogen could be result of complete mineralization. Photodegradation of CP in commercial product was more than its pure form. Commercial formulation accelerated photodegradation process; however no effect on biodegradation process was observed. After bio-photodegradation negligible toxicity for seeds of Triticum aestivum was observed. Study suggests an efficient treatment of wastewater containing CP and its metabolites in batch bioreactors could be achieved using P. alimentarius.
Synthesis of New Substituted Thiophene Derivatives and Evaluating their Antibacterial and Antioxidant Activities
Creators: name: Mehdhar, Fatima S.
name: Abdel-Galil, Ebrahim
name: Saeed, Ali
name: Abdel-Latif, Ehab
name: Ghani, Ghada E. Abd El
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology

description: p-Fluorophenacyl chloride (1) was used as a building block for the preparation of new tetra-substituted thiophene derivatives. The basic-catalyzed reaction of 1 with various thiocarbamoyl compounds such as 2-acetyl-2-substituted-thioacetanilides 2a,b, 3-arylazo-4-mercapto-4-phenylamino-buten-2-ones 5a–c, ethyl 2-arylazo-3-mercapto-3-phenylamino-acrylates 8a–c, N-aryl-2-cyano-3-mercapto-3-phenylamino-acrylamides 11a–c, N-aryl-2-(mercapto(phenylamino)methylene)-3-oxo-butanamides 14a–c, and 2-mercapto-4,6-dimethylnicotinonitrile 17 led to the production of their corresponding substituted thiophene compounds 4a–b, 7a–c, 10a–c, 13a–c, 16a–c, and 19 in moderate yields. The newly synthesized thiophene compounds were deduced according to FTIR, 1H NMR, 13C NMR, 19F NMR, and mass analyses along with micro-analytical data. The synthesized thiophene compounds were tested to evaluate their antibacterial and antioxidant activities. The majority of the synthesized thiophenes showed good to moderate anti-bacterial and antioxidant activities. The hydroxythiophene compound 4a showed extremely high antibacterial activity with inhibition zones 15–21 mm (from 60 to 87.5% activity indices). It inhibits bacterial growth and approaches the activity of Ampicillin, which inhibits bacteria with areas of inhibition from 23 to 25 mm. The hydroxythiophene compound 4a showed excellent antioxidant properties (85.9%) relative to the reference, Ascorbic acid (88.0%).
Applied Machine Learning for Information Security
Creators: name: Samtani, Sagar
name: Raff, Edward
name: Anderson, Hyrum
Publisher: name: ACM
Year: 2024
Subjects: applied machine learning
artificial intelligence
cybersecurity
deep learning
information security

description: Information security has undoubtedly become a critical aspect of modern cybersecurity practices. Over the last half-decade, numerous academic and industry groups have sought to develop machine learning, deep learning, and other areas of artificial intelligence-enabled analytics into information security practices. The Conference on Applied Machine Learning (CAMLIS) is an emerging venue that seeks to gather researchers and practitioners to discuss applied and fundamental research on machine learning for information security applications. In 2021, CAMLIS partnered with ACM Digital Threats: Research and Practice (DTRAP) to provide opportunities for authors of accepted CAMLIS papers to submit their research for consideration into ACM DTRAP via a Special Issue on Applied Machine Learning for Information Security. This editorial summarizes the results of this Special Issue.
Scholarly information repository services at Monash University
Creators: name: Harrison, Andrew
name: Clarke, Suzanne
name: Searle, Samantha
Publisher: name: figshare
Year: 2015
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: Monash University has a serious commitment to repositories and research data management. This is demonstrated by its leadership role in the National Systemic Information Infrastructure projects ARROW http://arrow.edu.au/, DART http://dart.edu.au/ and ARCHER http://archer.edu.au/ as well as the Monash University Information Management Strategy and specific data management activities. In recognition of its commitment to data management, Monash University is now the lead agent in the Australian National Data Service (ANDS) http://ands.org.au/. This is a national project which is working to develop good data management practice, collaboration, infrastructure and services. This paper outlines the development of government policy and programs in Australia as they relate to open access and the development of institutional repositories. It then provides an overview of the Monash University ARROW Repository http://arrow.monash.edu.au/vital/access/manager/Index. The main content of the paper is an examination of the way in which Monash University has responded to policy drivers around open access by establishing a complex, multi-purpose institutional repository that contains not only research publications, but also research data and multimedia research collections, providing discipline-specific support for publishing and dissemination. Conclusions are made about the future of the ARROW repositories and the learnings from the journey outlined above. Clarke, S.; Harrison, A.; Searle, S. Scholarly information repository services at Monash University. Presented at: IATUL 30th Annual Conference; 2009 Jun 1-4; Leuven, Belgium. 11 leaves.
Network agnosticism: Why networks must disappear
Creators: name: Barnet, Belinda
Publisher: name: Swinburne
Year: 2024

description: This article discusses pervasive computing as it relates to mobile content and mobile networks in particular, and argues that we need a unified networking concept that can bridge fixed and wireless networks and heterogeneous wireless technologies. It also discusses contemporary software applications that provide a content strategy that can transport a user's personal content and identity between networks, and calls for more work in this area. The article discusses current interconnectivity and interoperability between networks in Australia and recommends more work in this area.
Morpholine Stabilized on Nano Silica Sulfuric Acid: A Reusable Catalyst for the Synthesis of Two Important Derivatives (Thio) Barbituric Acid
Creators: name: Kakavand, Rodabeh
name: Azimi, Seyyedeh Cobra
name: Jolodar, Omid Gholi
name: Shirini, Farhad
name: Tajik, Hassan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Hematology

description: In this work, morpholine was stabilized on nano silica sulfuric acid. The stabilization process was confirmed using Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and thermogravimetric techniques. The obtained reagent was identified. Then it was used as a novel acidic reagent for the promotion of the synthesis of 5-aryl methylene barbituric and pyrano[2,3-d]pyrimidinone (thione) derivatives. The procedure leads to the requested products with excellent yields during very short reaction times. Also, the introduced catalyst can be reused for several times without considerable loss of its catalytic activity.
Reinforcement Learning-Based Offloading for RIS-Aided Cloud-Edge Computing in IoT Networks: Modeling, Analysis and Optimization
Creators: name: Zhang, Tiantian
name: Xu, Dongyang
name: Tolba, Amr
name: Yu, Keping
name: Song, Houbing
name: Yu, Shui
Publisher: name: IEEE
Year: 2024
Subjects: Optimization
Cloud computing
cloud-edge offloading
Energy consumption
Internet of Things
reconfigurable intelligent surface
Reconfigurable intelligent surfaces
Reinforcement learning
resource allocation
Task analysis
Wireless communication

description: The rapid advancement of wireless communication and artificial intelligence (AI) has led to a plethora of emerging applications that require exceptional connectivity, minimal latency, and substantial computing resources. The widespread adoption of cloud-edge intelligence is propelling the development of future networks capable of supporting intelligent computing. Mobile edge computing (MEC) technology facilitates the movement of computing resources and storage to the network’s edge, enabling cost-effective offloading of computational tasks for related applications which needs for reduced latency and improved energy efficiency. However, the offloading efficiency is hindered by limitations of wireless transmission capacity. This paper aims to address this issue by integrating reconfigurable intelligent surfaces (RISs) into a cell-free network within an intelligent cloud-edge system. The core idea is to strategically deploy passive RISs around base stations (BSs) to reconstruct the transmission channel and improve the corresponding capacity. Subsequently, we formulate an optimal problem involving joint beamforming for RISs and BSs, which is characterized by non-convexity and complexity. To tackle this challenge, we employ an alternating optimization scheme to ensure the effectiveness of joint beamforming. In particular, deep reinforcement learning (DRL) is leveraged to reduce the computational complexity involved in optimizing task offloading. Additionally, Lyapunov optimization is utilized to model the latency queue and improve the learning efficiency of the offloading framework. We conduct comprehensive evaluations on the wireless system’s capacity, average latency, and energy consumption, considering the integration of RIS with the DRL offloading framework. Experimental results demonstrate that our proposed scheme achieves superior efficiency and robustness.
High-energy extension of the gamma-ray band observable with an electron-tracking Compton camera
Creators: name: Oka, Tomohiko
name: Ogio, Shingo
name: Abe, Mitsuru
name: Hamaguchi, Kenji
name: Ikeda, Tomonori
name: Kubo, Hidetoshi
name: Kurosawa, Shunsuke
name: Miuchi, Kentaro
name: Mizumura, Yoshitaka
name: Nakamura, Yuta
name: Sawano, Tatsuya
name: Takada, Atsushi
name: Takemura, Taito
name: Tanimori, Toru
name: Yoshikawa, Kei
Publisher: name: Elsevier
Year: 2024
Subjects: Compton imaging
Gamma detectors
Gaseous detectors
Scintillators
Time projection chambers

description: Although the MeV gamma-ray band is a promising energy-band window in astrophysics, the current situation of MeV gamma-ray astronomy significantly lags behind those of the other energy bands in angular resolution and sensitivity. An electron-tracking Compton camera (ETCC), a next-generation MeV detector, is expected to revolutionize the situation. An ETCC tracks each Compton-recoil electron with a gaseous electron tracker and determines the incoming direction of each gamma-ray photon; thus, it has a strong background rejection power and yields a better angular resolution than classical Compton cameras. Here, we study ETCC events in which the Compton-recoil electrons do not deposit all energies to the electron tracker but escape and hit the surrounding pixel scintillator array (PSA). The PSA provides additional information on the electron-recoil direction, which enables us to improve significantly the angular resolution. We developed an analysis method for this untapped class of events and applied it to laboratory and simulation data. We found that the energy spectrum obtained from the simulation agreed with that of the actual data within a factor of 1.2. We then evaluated the detector performance using the simulation data. The angular resolution for the new-class events was found to be twice as good as in the previous study at the energy range 1.0–2.0 MeV, where both analyses overlap. We also found that the total effective area is dominated by the contribution of the double-hit events above an energy of 1.5 MeV. Notably, applying this new method extends the sensitive energy range with the ETCC from 0.2–2.1 MeV in the previous studies to up to 3.5 MeV. Adjusting the PSA dynamic range should improve the sensitivity in even higher energy gamma-rays. The development of this new analysis method would pave the way for future observations by ETCC to fill the MeV-band sensitivity gap in astronomy.
Experimental Spectroscopic, Structural (Monomer and Dimer), Molecular Docking, Molecular Dynamics Simulation and Hirshfeld Surface Analysis of 2-Amino-6-Methylpyridine
Creators: name: Fatima, Aysha
name: Singh, Meenakshi
name: Abualnaja, Khamael M.
name: Althubeiti, Khaled
name: Muthu, S.
name: Siddiqui, Nazia
name: Javed, Saleem
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: 2-Amino-6-methylpyridine (2-AMP) was investigated experimentally using FT-IR, 1H, NMR, and UV-Vis spectra, as well as theoretically using DFT calculations. The quantum computational calculations (the optimized structure, FT-IR, NMR and UV-Vis.) to support experimental data were performed by DFT approach at B3LYP functional and 6–311 + +G(d,p) basis set. The optimized molecular geometry and wavenumber calculations were done in the gas phase, while theoretical NMR was performed in Chloroform (CHCL3) solvation. The “Potential Energy Distribution analysis” (PED) of the title compound was performed with VEDA analysis and these assignments were compared with the experimental FT-IR spectrum. Hirshfeld analysis was also performed and analyzed intermolecular interactions on the surface of crystal, However, the most significant contributions to the Hirshfeld surface come from N···H (17.3%), C···H/H···C (23%) and H···H (68.8%). Chemical reactivity studies, Molecular Electrostatic Potential (MEP) maps, and surface area maps were also conducted. To show electron delocalization in the molecule, researchers used the electron localization function (ELF). Other topics included topological and mulliken charge distribution studies. Natural Bond Order Analysis (NBO) was performed to interpret intermolecular charge transfer.The effect of temperature on thermodynamical parameters such as Gibbs free energy, enthalpy, and entropy was examined. TD-DFT analysis was also used to shed more light on how the electronic transitions in the UV–Vis spectra were estimated. For different solvents, the estimated maximum wavelength (λ) absorbance and the band-gap energy of 2-AMP were calculated and compared to experimental results. The molecule's bioactivity is described theoretically using the Electrophilicity index and the interaction between the ligand-protein is depicted using Molecular docking. The proteins 3DQS, 4UX6, 5ADF, 5TUD, and 6E9L were studied via molecular docking. The nature of the molecule was determined by its drug-likeness. A molecular dynamics simulation was used to explore biomolecular stability.
Molecular Docking, Dynamic Simulation and DFT Approach to Noble “2-Hydrazinobenzothiazole” Compound
Creators: name: Sharma, Arun
name: Fatima, Aysha
name: Malla, Manzoor A.
name: Khanum, Ghazala
name: Kumar, Anuj
name: Singh, Meenakshi
name: Abualnaja, Khamael M.
name: Althubeiti, Khaled
name: Muthu, S.
name: Siddiqui, Nazia
name: Javed, Saleem
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biophysics
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The ligand-protein complex was studied using an MD simulation. It provides a comprehensive grasp of a biomolecular system's dynamics, mechanism, and atom’s nature. Two distinct receptors have been docked with the target drug 2-Hydrazinobenzothiazole (2-HBT), also known as 1,3-benzothiazol-2-ylhydrazine (IUPCA name). All obtained observations of the 2-Hydrazinobenzothiazole drug are discussed with appropriate literature survey. Density functional theory using the higher-order basis set 6-311++G was used to determine the theoretical traits and characteristics. The spectroscopic characterizations of FT-IR, FT-Raman, UV-visible, and NMR were calculated throughout this work. This research adds to the examination of a pharmaceutically active “2-Hydrazinobenzothiazole” drug's geometrical structure, vibrational spectra, and corresponding assignments as well as PED values with electrical, thermodynamic, optical, and nonlinear properties. Theoretically and experimentally observed results of all characterizations were compared, including NMR, UV–visible, infrared, and Raman spectroscopy. The named drug exhibits good biological activity in nature, as demonstrated theoretically by molecular docking. Time-dependent density function theory (TD-DFT) highlighted the contrast in between Highest occupied (HOMO) and lowest unoccupied molecular orbital (LUMO) energy gap with UV absorption spectra. Besides , in Infrared and Raman characterization vibration spectra, a scaling factor eliminates the solid-to-gas phase transition.
Solution to the information paradox: Quantum Imagination Theory
Creators: name: Kitchen, Kris
Publisher: name: figshare
Year: 2015
Subjects: subject: Applied Physics
subject: M-Theory
subject: 20203 Particle Physics
subject: FOS: Physical sciences
subject: Plasma Physics
subject: Condensed Matter Physics
subject: Mechanics
subject: Thermodynamics
subject: Entropy
subject: Quantum Mechanics
subject: Special Relativity
subject: General Relativity
subject: Atomic Physics
subject: Computational Physics
subject: 91308 Solid Mechanics
subject: FOS: Mechanical engineering

description: Grand Unification Theory determined by Quantum Imagination Theory This appears to also be a solution to the information paradox
A Large Model’s Ability to Identify 3D Objects as a Function of Viewing Angle
Creators: name: Rubinstein, Jacob
name: Ferraro, Francis
name: Matuszek, Cynthia
name: Engel, Don
Publisher: name: IEEE
Year: 2024

description: Virtual reality is progressively more widely used to support embodied AI agents, such as robots, which frequently engage in ‘sim-to-real’ based learning approaches. At the same time, tools such as large vision-and-language models offer new capabilities that tie into a wide variety of tasks and capabilities. In order to understand how such agents can learn from simulated environments, we explore a language model’s ability to recover the type of object represented by a photorealistic 3D model as a function of the 3D perspective from which the model is viewed. We used photogrammetry to create 3D models of commonplace objects and rendered 2D images of these models from an fixed set of 420 virtual camera perspectives. A well-studied image and language model (CLIP) was used to generate text (i.e., prompts) corresponding to these images. Using multiple instances of various object classes, we studied which camera perspectives were most likely to return accurate text categorizations for each class of object.
The Solana del Zamborino: Rediscovering a Late Middle Pleistocene Open-Air Campsite Half a Century Later (Granada, Spain)
Creators: name: Solano García, José Antonio
name: Lombera Hermida, Arturo
name: Serrano Ramos, Alexia
name: Sánchez Bandera, Christian
name: Herranz Rodrigo, Darío
name: Ortiz, Elisabeth
name: Gonzalez-Quiñones, Juan-José
name: Ochando Tomás, Juan
name: Gutiérrez Rodríguez, Mario
name: Jimenez-Arenas, Juan Manuel
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Prehistory
subject: Archaeology
subject: Middle Pleistocene
subject: Spain
subject: Lithic industry

description: The Solana del Zamborino: Rediscovering a Late Middle Pleistocene Open-Air Campsite Half a Century Later (Granada, Spain)

 

José A. Solano1*, Alexia Serrano-Ramos1, Christian Sánchez-Bandera2, Darío Herránz1, Elisabeth Ortiz1, Juan José González-Quiñones1, Juan Ochando3, Mario Gutiérrez4, Arturo de Lombera-Hermida5, Juan Manuel Jiménez-Arenas1.

1University of Granada, Spain.

2Institut Català de Paleoecologia Humana i Evolució Social, Spain.

3University of Murcia, Spain.

4University of Jaén, Spain.

5University of Oviedo, Spain.

 *Correspondence: solano@ugr.es

Keywords: Revisiting a site, Open-air camp, use of fire, Late Middle Pleistocene, southern Iberian Peninsula.

Mesopleistocene open-air sites with good preservation are rather scarce. These types of locations provide us with information about human activity and its interaction with the environment, which is different and complementary to cave sites.

La Solana del Zamborino is a rich multi-layered site, with nearly 10 meters of archaeological depth, located in the centre of the Guadix endorheic basin (Fonelas, Granada). Between 1972 and 1978, six excavation seasons were conducted, of which only the first two were published, along with a few subsequent studies of paleontological and archaeological research. These pioneering multidisciplinary works highlighted the significance of the site due to its rich archaeological and faunal record within a fluvial-marshy paleoenvironmental context during the Middle Pleistocene. Moreover, not only were traces of fire detected, but also a possible hearth structure delimited by stones was documented.

Recognising the importance of the site, various attempts at magnetostratigraphic dating have sparked lively ongoing debates, yet no archaeological excavation activities had been undertaken until 2024. Through a new stratigraphic survey, our overarching goal aims to address questions regarding human behaviour and activities outside their shelter/habitat zones and their interaction in open environments. To achieve this, we have implemented archaeological interventions primarily focused on recovering all analytical samples that allow us to reconstruct the formation of the site and the paleoenvironment in its diachronic development.

We present the new multidisciplinary project that has been launched and a preliminary report on the first excavation campaign, during which a substantial amount of lithic industry has been recovered and the initial sets of analytical samples have been taken.
“No Safe Spaces”: The Retraumatization and Dehumanization of Immigrant Survivors of Domestic Violence in the United States
Creators: name: Nayak, Sameera Shukanta
name: Efimov, Xenia
name: Ncube, Collette N.
name: Griffith, John
name: Molnar, Beth E.
Publisher: name: Taylor and Francise
Year: 2023
Subjects: Domestic violence
Immigrant health
Legal status
Structural discrimination
Undocumented

description: Immigrants in the United States suffer high rates of domestic violence (DV). Using data from six focus groups with 38 DV service providers, we examined how immigrant survivors navigate an often-hostile political climate and identified structural barriers to healing and help-seeking. Findings indicated that structural discrimination, social exclusion, and dehumanization compound existing trauma and negatively impact survivors’ well-being. Results underscore the need to restructure pathways of immigration relief such as the U Visa and the Violence Against Women Act (VAWA) Self-Petition. Structural interventions targeting the immigration system and enhancing access to more secure legal status could serve to augment population health.
Alignment of state-level policies and public attitudes towards abortion legality and government restrictions on abortion in the United States
Creators: name: Scoglio, Arielle A. J.
name: Nayak, Sameera Shukanta
Publisher: name: Elsevier
Year: 2023
Subjects: Abortion access
Government restrictions
Public attitudes
State policy

description: Background Contextual factors can shape public opinion towards abortion. We investigated the association between the state-level abortion legislative climate and individual attitudes towards abortion legality and government restrictions of abortion access in the United States. Methods Data come from the 2020 Cooperative Congressional Election Study (n = 61,000). Using multivariable logistic regression with generalized estimating equations, we explored whether state-level abortion policy climates (based on the Guttmacher Institute’s 2020 rating of state abortion policies) were associated with individual attitudes (1) towards abortion legality, and (2) towards government restriction of abortion access, controlling for individual socio-demographic factors. Results Eighty-eight percent of participants supported the legality of abortion in some or all circumstances. Conversely, 30% of the sample opposed all federal government restrictions on abortion. More than 60% of the sample lived in highly abortion-restrictive states. Participants living in states with a more supportive abortion legislative climate were more likely to support the legality of abortion in some or all circumstances (AOR = 1.07, (95% CI 1.05, 1.09). Participants in states with more supportive abortion policies were more likely to oppose federal governmental restrictions (AOR = 1.03, 95% CI 1.02, 1.04). Low religiosity, higher educational attainment, and politically liberal views were associated with increased support for abortion legality and increased opposition to government restrictions on abortion. Conclusions State-level abortion policy contexts were positively associated with public attitudes towards abortion. While attitudes towards abortion legality are favorable across the country; there is also strong support at least one type of government restriction on abortion access. Results highlight a disconnect between multifaceted public attitudes towards abortion and polarized state contexts, suggesting that policymaking on abortion represents a higher level of polarization than exists at the individual level. Policymakers and legislators should more carefully consider the desires of the public when designing abortion legislation.
Martin Austermuhle on WAMU Layoffs
Creators: name: Dasgupta, Sunil
name: Austermuhle, Martin
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: I Hate Politics

description: Listen to this episode from I Hate Politics Podcast on Spotify. In yet another setback to news reporting, Washington DC public radio station WAMU closes its local news website, DCist, and lays off 16 staffers. Sunil Dasgupta talks with longtime WAMU and DCist reporter Martin Austermuhle about how mismanagement killed a popular news source. Austermuhle left the station on his own a few months before the layoffs and is not bound by a non-disparagement agreement. Music from DC garage punk band, Apollo 66: apollo66rock.com.
Biotreatment of chlorpyrifos in a bench scale bioreactor using Psychrobacter alimentarius T14
Creators: name: Saira Khalid
name: Hashmi, Imran
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Microbiology
subject: FOS: Biological sciences
subject: Engineering
subject: Biochemistry

description: Bacteria tolerant to high pesticide concentration could be used for designing an efficient treatment technology. Bacterial strains T14 was isolated from pesticide-contaminated soil in mineral salt medium (MSM) and identified as Psychrobacter alimentarius T14 using 16S rRNA gene sequence analysis. Bench scale bioreactor was evaluated for biotreatment of high Chlorpyrifos (CP) concentration using P. alimentarius T14. Effect of various parameters on bioreactor performance was examined and optimum removal was observed at optical density (OD600 nm): 0.8; pH: 7.2; CP concentration: 300 mg L−1 and hydraulic retention time: 48 h. At optimum conditions, 70.3/79% of CP/chemical oxygen demand (COD) removal was achieved in batch bioreactors. In addition, P. alimentarius T14 achieved 95/91, 62.3/75, 69.8/64% CP/COD removal efficiency with addition of CS (co-substrates), CS1 (yeast extract + synthetic wastewater), CS2 (glucose + synthetic wastewater) and CS3 (yeast extract), respectively. Addition of CS1 to bioreactor could accelerate CP removal rate up to many cycles with considerable efficiency. However, accumulation of 3, 5, 6-trichloro-2-pyridinol affects reactor performance in cyclic mode. First-order rate constant k1 0.062 h−1 and t1/2 11.1 h demonstrates fast degradation. Change in concentration of total chlorine and nitrogen could be the result of complete mineralization. Photodegradation of CP in commercial product was more than its pure form. Commercial formulation accelerated photodegradation process; however no effect on biodegradation process was observed. After bio-photodegradation, negligible toxicity for seeds of Triticum aestivum was observed. Study suggests an efficient treatment of wastewater containing CP and its metabolites in batch bioreactors could be achieved using P. alimentarius.
Surface Modification of Nerve Guide Conduits with ECM Coatings and Investigating Their Impact on Schwann Cell Response
Creators: name: Pinzon-Herrera, Luis
name: Magness, John
name: Apodaca-Reyes, Hector
name: Sanchez, Jesus
name: Almodovar, Jorge
Publisher: name: Wiley
Year: 2024
Subjects: collagen
heparin
human Schwann cells
layer-by-layer
NGCs
tissue engineering

description: In this study, layer-by-layer coatings composed of heparin and collagen are proposed as an extracellular mimetic environment on nerve guide conduits (NGC) to modulate the behavior of Schwann cells (hSCs). The authors evaluated the stability, degradation over time, and bioactivity of six bilayers of heparin/collagen layer-by-layer coatings, denoted as (HEP/COL)₆. The stability study reveals that (HEP/COL)₆ is stable after incubating the coatings in cell media for up to 21 days. The impact of (HEP/COL)₆ on hSCs viability, protein expression, and migration is evaluated. These assays show that hSCs cultured in (HEP/COL)₆ have enhanced protein expression and migration. This condition increases the expression of neurotrophic and immunomodulatory factors up to 1.5-fold compared to controls, and hSCs migrated 1.34 times faster than in the uncoated surfaces. Finally, (HEP/COL)₆ is also applied to a commercial collagen-based NGC, NeuraGen, and hSC viability and adhesion are studied after 6 days of culture. The morphology of NeuraGen is not altered by the presence of (HEP/COL)₆ and a nearly 170% increase of the cell viability is observed in the condition where NeuraGen is used with (HEP/COL)₆. Additionally, cell adhesion on the coated samples is successfully demonstrated. This work demonstrates the reparative enhancing potential of extracellular mimetic coatings.
title: Variation in the structure and function of invertebrate-associated bacterial communities
Creators: name: Blow, F
Publisher: name: University of Liverpool Repository
Year: 2017

description: Microorganisms are intricately involved in the ecology of many insects, often contributing to host fitness and forming evolutionarily stable associations. The interactions between hosts and microbes can significantly alter their evolutionary trajectories, enabling them to adapt to novel environmental conditions. In this thesis I have examined how host ecology can shape the interactions of bacteria with insects of agricultural and epidemiological importance. I have described the bacterial communities associated with Bactrocera oleae (the olive fruit fly) and generated draft genome sequences for several members of the gut microbiota, including the symbiotic bacterium “Candidatus Erwinia dacicola”. Comparative genomic analyses indicate that Ca. E. dacicola and a novel facultative bacterium Tatumella TA1 may perform key nutritional functions for the host, including the synthesis of essential amino acids and ammonia assimilation from host nitrogenous waste products. Tatumella TA1 is consistently associated with all life stages of populations collected in Israel and Crete at low relative abundance, and encodes large adhesion proteins that may assist in attachment to the host epithelium or other members of the microbiota in the B. oleae gut. I have also examined the variation in frequency and relative abundance of facultative microbes that infect several Glossina spp. (the tsetse fly): the sole vector of African trypanosomes in Sub-Saharan Africa. In addition to three vertically transmitted endosymbionts (Wigglesworthia, Sodalis, and Wolbachia), tsetse flies are infected with two additional potential reproductive manipulators: Spiroplasma and Rickettsia, and a novel strain of Klebsiella. The draft genomes generated for these taxa over the course of this thesis provide the opportunity for future studies in to their role in host biology and how community interactions can shape the transmission and evolutionary dynamics of host-associated microbes.
title: Examining the socio-cultural context of fishing lives on the Llŷn Peninsula, UK
Creators: name: Gustavsson, M
Publisher: name: University of Liverpool Repository
Year: 2017

description: It has been argued that socio-cultural aspects of fisheries sustainability have been omitted in favour of environmental and economic perspectives within marine and fisheries policy. Responding to recent calls to pay greater attention to these overlooked aspects, this thesis is examining fishing lives (including those of fishing family members) in their socio-cultural contexts. This is done by drawing on Bourdieu’s conceptual ideas of habitus, field and capital alongside three additional literatures: i) the application of Bourdieu’s ideas in the ‘good farmer’ literature, ii) the lifecourse approach, and iii) the gender identity lens – which taken together seeks to understand how fishing capitals are acquired over time from different positions within the fishing field. The research utilises qualitative semi-structured interviews and participant observation in a case study of the Llŷn peninsula small-scale fishery to investigate the socio-cultural context of fishing lives. A number of important contributions to the wider fisheries social sciences are made. First of all, the thesis develops the new conceptual idea of the ‘good fisher’ which is constructed around the display of embodied cultural capital alongside fishers’ reputation of complying with the unwritten ‘rules of the game’. Secondly, the thesis finds that the socio-cultural contexts are important for getting on the ‘fishing ladder’, and interrelated to this, the fishing lifecourse is linked across generations. A third contribution is that fishers construct a ‘localised socially dominant masculinity’ in which fishing masculinities are hybrid, multiple and situated. As a final point the thesis found that the pre-existing socio-cultural contexts are important for how fishers respond to marine and fisheries policy schemes and it is suggested that new policies need to recognise these contexts to be environmentally as well as culturally sustainable.
Reframing family homelessness: A citizenship approach
Creators: name: Hulse, Kathleen
name: Spinney, Angela
name: Kolar, Violet
Publisher: name: Swinburne
Year: 2024

description: This is the first paper from a project which draws on recent scholarship about citizenship, emphasising gender, culture and place (e.g. Lister, 2007), to develop a richer understanding of homelessness experienced by families with children, predominantly women with children This scholarship suggests that citizenship is not confined to formal relations between citizens and the state but also includes other types of relationships between citizens, some of which occur in the private rather than the public sphere. According to this work, citizenship is more than a formal statement of rights and responsibilities; it is practised on a day-to-day basis through a series of individual and cumulative interactions between people. The research frames the experiences of the homeless families in terms of 'citizenship as practice' (Desforges, Jones & Woods, 2005) and seeks to understand the everyday lived experience of homelessness. This paper presents the early findings from the first wave of a qualitative, longitudinal research project which enables families to detail and interpret their lived experiences as they deal with homelessness and attempt to improve their lives. The research findings suggest that homeless families have to make many compromises in daily practices in order to access crisis and transitional housing and that these compromises, as well as their material circumstances, affect their sense of control and agency in critical ways.