cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Die Europaschule-Linz
Creators: name: Leeb, Johannes
name: Soukup-Altrichter, Katharina
Publisher: name: WE_OS Jahrbuch
Year: 2020

description: Die Europaschule-Linz ist eine Schule der Sechs- bis Vierzehnjährigen und vereint die Praxisvolksschule sowie die Praxismittelschule der Pädagogischen Hochschule Oberösterreich. Um das gesamte Bildungsspektrum an Schüler*innen abzubilden, werden bewusst in jedem Jahrgang Kinder mit unterschiedlichsten soziökonomischen Hintergründen und Kinder mit Sonderpädagogischem Förderbedarf aufgenommen, in die einzelnen Klassen integriert und somit Inklusion erleb- und erfahrbar gemacht. Hochqualifizierte Pädagog*innen arbeiten daran, auf Basis von Erkenntnissen aus der pädagogischen Forschung selbst Modelle in den Bereichen der Schulorganisation, Fachdidaktik und Unterrichtsentwicklung umzusetzen und auf ihre Praxistauglichkeit hin zu beforschen. The “Europaschule” Linz is a school for 6 to 14 year old students and combines the training school “Volksschule” and the training school “Neue Mittelschule” of the Teacher Training College Upper Austria. In order to cover the entire educational spectrum of pupils, each class consciously includes children from different socio-economic backgrounds and children with special educational needs, integrates them into the individual classes, and thus makes inclusion a tangible experience.
description: WE_OS Jahrbuch, Bd. 3 (2020): Kooperation von Universitäten und Schulen – Gründungsschrift des Verbunds Universitäts- und Versuchsschulen (VUVS)
title: Projets d'intégration et pratiques collaboratives entre pédagogues en éducation précoce spécialisée et enseignants, lors de la première transition vers l'école
title: Projets d'intégration et pratiques collaboratives entre pédagogues en éducation précoce spécialisée et enseignants, lors de la première transition vers l'école
titleType: AlternativeTitle
Creators: name: Tonti-Vuillaume, Emilie
Publisher: name: Unknown
Year: 0
Subjects: subject: transition scolaire
subject: collaboration
subject: éducation précoce spécialisée
subject: besoins éducatifs particuliers
subject: intégration
subject: éducation inclusive

description: Ce travail de mémoire réalisé en vue de l’obtention de la Maîtrise universitaire en éducation précoce spécialisée, est une recherche menée auprès de quatre enseignantes de 1ère primaire HarmoS et de quatre pédagogues du Service Educatif Itinérant, dans le canton de Fribourg. La recherche pose la question de la collaboration interprofessionnelle, lors de la première transition scolaire d’enfants à besoins spécifiques, vers l’école régulière. Plus précisément, cette étude cherchera à découvrir quelles sont les expériences de collaboration entre enseignantes et pédagogues SEI et quel regard elles portent sur les effets de leur collaboration pour les projets d’intégration. Les enjeux relatifs aux pratiques collaboratives, en termes d’obstacles et de facilitateurs, seront également étudiés. Finalement, ce travail alerte sur l’importance de soigner l’entrée en scolarité d’enfants à besoins éducatifs particuliers et sur les enjeux relatifs à l’accompagnement de cette étape.
Die „Heliosschulen – Inklusive Universitätsschulen der Stadt Köln“
Creators: name: Hensel, Marion
name: Niessen, Andreas
name: Reuther, Ellen
name: Rosen, Lisa
name: Sehnbruch, Lucia
name: Şengüler, Burak
name: Weber, Birgit
name: Werker, Bünyamin
Publisher: name: WE_OS Jahrbuch
Year: 2020

description: Während zu dem Gründungskonzept der „Heliosschulen – Inklusive Universitätsschulen der Stadt Köln“ bereits vergleichsweise viele Publikationen insbesondere mit Blick auf Inklusion existieren (Reich, 2014, 2019; Reich, Asselhoven & Kargl, 2015), wollen wir in diesem Beitrag gewissermaßen einen Blick hinter die Kulissen werfen und weniger das pädagogische Konzept in den Vordergrund stellen, sondern die Entwicklung der Heliosschulen als Universitätsschulen. Zum einen werden wir die Gründungsgeschichte skizzieren und dazu auf ein zentrales Vorläuferprojekt an der Universität zu Köln eingehen. Zum anderen werden wir Meilensteine im Projektverlauf darstellen, wie den Spatenstich des Neubauvorhabens der Universitätsschule sowie aktuelle Initiativen der Wissenschaftlichen Leitung, die dazu dienen, die Universitätsschulen sowohl als Forschungsschulen als auch als Ausbildungsschulen zu konturieren. While there are already many publications on the founding concept of the “Helios Schools – Inclusive University Schools of the City of Cologne”, especially with regard to inclusion (Reich, 2014, 2018; Reich, Asselhoven & Kargl, 2015), in this article we want to take a look behind the scenes and focus less on the pedagogical concept and more on the development of the Helios Schools as university schools. On the one hand, we will outline the history of the founding of the Helios Schools and, in this context, we will look at a central predecessor project at the University of Cologne. On the other hand, we will present milestones in the course of the project, such as the ground-breaking for the construction of the new university schools and current initiatives of the scientific management, which serve to define the university schools both as research schools and as training schools.
description: WE_OS Jahrbuch, Bd. 3 (2020): Kooperation von Universitäten und Schulen – Gründungsschrift des Verbunds Universitäts- und Versuchsschulen (VUVS)
Why do mutant allele frequencies in oncogenes peak around .40 and rapidly decrease?
Creators: name: Kasthuri Kannan
name: Heguy, Adriana
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: The mutant allele frequencies in oncogenes peak around .40 and rapidly decrease. In this article, we explain why this is the case. Invoking a key result from mathematical analysis in our model, namely, the inverse function theorem, we estimate the selection coefficients of the mutant alleles as a function of germline allele frequencies. Under complete dominance of oncogenic mutations, this selection function is expected to be linearly correlated with the distribution of the mutant alleles. We demonstrate that this is the case by investigating the allele frequencies of mutations in oncogenes across various cancer types, validating our model for mean effective selection. Consistent with the population genetics model of fitness, the selection function fits a gamma-distribution curve that accurately describes the trend of the mutant allele frequencies. While existing equations for selection explain evolution at low allele frequencies, our equations are general formulas for natural selection under complete dominance operating at all frequencies. We show that selection exhibits linear behaviour at all times, favouring dominant alleles with respect to the change in recessive allele frequencies. Also, these equations show, selection behaves like power law against the recessive alleles at low dominant allele frequencies.
Laborschule Bielefeld
Creators: name: Textor, Annette
name: Devantié, Rainer
name: Dorniak, Marlena
name: Gold, Johanna
name: Zenke, Christian Timo
name: Zentarra, Dominik
Publisher: name: WE_OS Jahrbuch
Year: 2020

description: In diesem Beitrag wird zunächst anhand ausgewählter Themenbereiche das Konzept der Laborschule Bielefeld dargestellt. So wird der Großraum als Rahmen für das Lernen beschrieben, und es werden die Aktivitäten und die Organisation im Bereich der Inklusion und des Lernens durch Erfahrung vorgestellt. Anschließend wird das Modell der Forschung und Entwicklung an der Laborschule thematisiert. Insbesondere wird der Fokus auf die Strukturen und Prozesse gelegt, die die Praxisforschung an der Laborschule unterstützen. In this article, first, the concept of the Laborschule (Laboratory School) Bielefeld is presented using selected topics. Thus, the open plan layout of the school building is described as a framework for learning as well as the activities and organization in the field of inclusion and learning by experience. Second, the model of research and development at the Laboratory School is discussed. The focus lies, in particular, on the structures and processes that support action research at the Laboratory School.
description: WE_OS Jahrbuch, Bd. 3 (2020): Kooperation von Universitäten und Schulen – Gründungsschrift des Verbunds Universitäts- und Versuchsschulen (VUVS)
Strategische Partnerschaft zwischen dem Institut für Erziehungswissenschaft der Universität Kassel und Versuchsschulen des Landes Hessen als Impuls für Schulentwicklung und Forschung
Creators: name: Hofmann, Julia
name: Koch, Barbara
name: Kuhn, Hans Peter
Publisher: name: WE_OS Jahrbuch
Year: 2020

description: In diesem Beitrag wird die strategische Partnerschaft zwischen dem Institut für Erziehungswissenschaft der Universität Kassel und Versuchsschulen des Landes Hessen präsentiert. Dazu werden die Akteure der Zusammenarbeit vorgestellt. Es wird die Form der Zusammenarbeit erläutert und an zwei Forschungsprojekten illustriert. Erkennbar wird, dass durch die unterschiedlichen Formate der Zusammenarbeit Impulse für die Entwicklung von Schulen und für die Gewinnung erziehungswissenschaftlicher Erkenntnisse entstehen. The article presents the strategic partnership between the Institute of Educational Science of the University of Kassel and experimental schools of the state of Hesse. For this purpose, the actors of the cooperation are presented. The form of cooperation is explained and illustrated by two research projects. It becomes apparent that the different formats of cooperation generate impulses for school development and for the acquisition of educational science knowledge.
description: WE_OS Jahrbuch, Bd. 3 (2020): Kooperation von Universitäten und Schulen – Gründungsschrift des Verbunds Universitäts- und Versuchsschulen (VUVS)
Can we play together? Inclusive playgrounds as an example to enhance resilience in public spaces
Creators: name: Wenger, Ines
name: Schulze, Christina
name: Lundström, Ulrica
name: Prellwitz, Maria
Publisher: name: Zenodo
Year: 2021
Subjects: outdoor play, inclusion, inclusive playground

description: Background: Play is one of the central occupations of children and essentially contributes to children’s physical,
 cognitive and social development, wellbeing and participation in society. The playground, as a public space,
 provides children with opportunities for play, social interaction and participation and can become a place to
 build resilience. For children with disabilities, however, participation in playgrounds is often limited due to
 environmental barriers.
 Objective: The project aims to identify resources and challenges regarding the participation and inclusion of
 children with and without disabilities on inclusive playgrounds.
 Methods: Observations of children playing on six inclusive playgrounds located in Switzerland have been collected.
 The observations were explored with a transactional perspective.
 Results: The application of universal design in the construction of inclusive playgrounds enables all children to
 participate. However, children with disabilities are rarely socially included on inclusive playgrounds. Suggestions
 to apply a transactional perspective as one way to enhance social inclusion and help to build up resilience
 will be illustrated.
 Conclusion: Considering occupational science theories could enable occupational therapist to become active on
 community level and to increase social inclusion and resilience on public playgrounds.
Impact des programmes d'accompagnement financière de soutien à l'entrepreneuriat des jeunes et inclusion financière au Maroc
Creators: name: Souad EL MORABIT
name: Abid ihadiyan
name: Achoura Nadia JARIDI
Publisher: name: Zenodo
Year: 2024

description: L'inclusion financière au Maroc vise à rendre les services financiers accessibles à tous, y compris aux exclus du système traditionnel. Des initiatives telles que l'extension des services bancaires en zones rurales, les solutions financières mobiles, et la sensibilisation à une gestion financière saine ont été mises en place.

En parallèle, le Maroc soutient l'entrepreneuriat des jeunes à travers des programmes de formation, des subventions, des prêts à taux avantageux, et la création d'incubateurs et d'espaces collaboratifs. L'inclusion financière est cruciale pour le succès de ces programmes, permettant aux jeunes entrepreneurs d'accéder aux financements nécessaires pour lancer et développer leurs projets.

Ces efforts visent à encourager l'indépendance économique des jeunes, stimuler l'innovation et la création d'emplois, et promouvoir un développement économique durable, créant ainsi un environnement propice à l'émergence de nouveaux entrepreneurs dynamiques et créatifs.
The Effects of Maternal Under-Nutrition and a Post-Natal High Fat Diet on Lens Growth, Transparency and Oxidative Defense Systems in Rat Offspring
Creators: name: Sachini K. Jayaratne
name: Donaldson, Paul J.
name: Vickers, Mark H.
name: Lim, Julie C.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Computational Biology

description: Purpose: A poor early life nutrition environment is well established to result in a range of cardiometabolic disorders in offspring in later life. These effects can be exacerbated via exposure to an obesogenic dietary environment. To date, the effect of maternal diet and/or a post-natal obesogenic nutritional environment on key characteristics related to lens growth and oxidative stress has not been undertaken. The present study, therefore, examined the characteristics and oxidative status of the lens. Materials and Methods: Using a model of moderate maternal under-nutrition, rat dams were fed either a control diet (100% ad libitum, CON) or undernourished throughout pregnancy (50% of ad libitum intake, UN) and offspring fed either a control (5% fat, C) or high fat (30% fat, HF) diet post-weaning, resulting in four nutritional groups; CON-C, CON-HF, UN-C, and UN-HF. Offspring lenses were extracted at 160 days of age, weighed, imaged under dark and bright field microscopy, and then dissected into cortical and core fractions for biochemical analyses of oxidative stress markers. Results: Our findings reveal that lenses from all groups were transparent. However, gender specific changes were evident at the biochemical level with increased oxidative stress detected in the cortex and core of female but not male UN-C lenses, and in the cortex of male but not female CON-HF lenses. The greatest increase in oxidative stress was detected in the UN-HF group in the cortex and core regions of the lens and for both genders. Conclusions: These findings show that oxidative stress is exacerbated in the lens as a result of a combination of altered pre-natal and post-natal diet. This demonstrates a novel interaction between the two developmental windows and warrants further investigations toward devising appropriate nutritional strategies for minimizing oxidative stress in the lens.
Children's perceptions of factors enhancing play value and inclusion on outdoor playgrounds: a synthesis of qualitative evidence
Creators: name: Wenger, Ines
name: Lynch, Helen
name: Prellwitz, Maria
name: Schulze, Christina
Publisher: name: Zenodo
Year: 2021

description: The protocol describes the review question, search strategy, and inclusion and exclusion criteria for a synthesis of qualitative evidence about children's perceptions of factors enhancing play value and inclusion on outdoor playgrounds. Furthermore, it contains information about the planned data extraction process, quality assessment, and data synthesis procedure.
Spiel, Spass und Spannung am Spielplatz : welche Rolle spielt die Umwelt?
Creators: name: Morgenthaler, Thomas
name: Schulze, Christina
Publisher: name: Zenodo
Year: 2022
Subjects: outdoor play
occupational therapy
experience of fun
playground

description: Ergotherapeutinnen/-therapeuten schätzen Spiel als die Hauptbetätigung von Kindern. Je doch wird Spiel eher als Mittel zum Zweck eingesetzt, um Fertigkeiten zu trainieren und Entwicklung voranzutreiben. Im Gegensatz dazu erleben Kinder das Spiel als Prozess der Freude und Spass. Es ermöglicht ihnen, mit Freunden zusammen zu sein, selbst Entscheidungen zu treffen, was/wie sie spielen möchten und neue Herausforderungen zu meistern. Öffentliche Spielplätze werden regelmässig von Kindern und Familien besucht und sind ein wichtiger Teil in ihrem Alltag. Nicht alle Kinder können gleichermassen vom Spielplatz profitieren und manche Spielplätze werden von Kindern als langweilig empfunden. In der Ergotherapie werden Umweltaspekte erhoben, welche sich förderlich und/oder hinderlich auf das Spiel auswirken können. Durch eine Anpassung der Umwelt können Bedingungen geschaffen werden, die Spiel von Kindern unterstützen. In diesem Vortrag wird ein internationales Forschungsprojekt vorgestellt, welches Umweltaspekte auf dem Spielplatz untersucht und das Ziel verfolgt, ein ergotherapeutisches Assessment zu entwickeln. Dieses Basislager bietet Raum zum Vernetzen von Expertinnen/Experten und Interessierten rund um das Thema Spielen am Spielplatz und Spiel in der pädiatrischen Ergotherapie.
Characterization of Rabbit Corneas Subjected to Stromal Stiffening by the Açaí Extract (Euterpe oleracea)
Creators: name: Bersanetti, Patrícia A.
name: Tatiane L. N. Bueno
name: Morandim-Giannetti, Andreia De A.
name: Nogueira, Regina F.
name: Jivaldo R. Matos
name: Schor, Paulo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Purpose: In this study, we characterized rabbit corneas subjected to corneal cross-linking (CXL) with açaí extract compared with a riboflavin photo-stimulated procedure. Materials and Methods: The corneas of the slaughterhouse rabbits were divided into three groups: control, consisting of untreated corneal samples; riboflavin/UVA, where corneas were treated with 0.1% riboflavin photo-stimulated at 365 nm as the standard protocol; and açaí, where the samples were subjected to 4% açaí extract for 0.5–2 h. After the CXL procedure, corneas of the three groups were characterized by analyzing their elastic modulus and thermal denaturation profile. Results: The elastic modulus at 3% strain showed an approximately threefold increase in the riboflavin/UVA group and 10.5 times in the corneas treated with 4% açaí extract for 2 h, compared with the control group (p < 0.01). The denaturation temperature values of the two groups of crosslinked corneas increased significantly (p < 0.05) and were more pronounced in the açaí group. Conclusions: The açaí extract was effective in promoting CXL in rabbit corneas as characterized by the different techniques.
Auf dem Weg. Aachener Kooperationsverbund
Creators: name: Haupt, Selma
name: Hering, Sabine
name: Unger, Tim
Publisher: name: WE_OS Jahrbuch
Year: 2020

description: Ausgehend von der Unzufriedenheit der Lehrenden und Studierenden in den Bildungswissenschaften haben wir uns auf den Weg gemacht, die Aachener Lehrer*innenbildung zu verändern. Unsere zentrale Frage ist dabei: Wieviel Freiheit für Persönlichkeitsentwicklung können wir im bildungswissenschaftlichen Studium ermöglichen und gleichzeitig die Qualität der Lehramtsausbildung garantieren? Unser Anliegen ist es, sowohl für uns als auch für die Studierenden die Veränderungen zu durchleben, die notwendig sind, um Innovationen im Bildungssystem – in der Schule wie im Lehramtsstudium – mitzugestalten. Unser Ansatz liegt darin, Kooperation in Forschung und Lehre zu praktizieren, als Lehrende und als Wissenschaftler*innen. Der Aachener Kooperationsverbund befindet sich auf dem Weg. Realisiert sind bereits das Denkkollektiv, die Aachener Bildungsgespräche und einige Kooperationen mit Schulen. Auf dem weiteren Weg wollen wir daran festhalten, gemeinsam Veränderung zu durchleben und Innovationen mitzugestalten. Based on the dissatisfaction of teachers and students in the educational sciences, we have set out to change teacher education in Aachen. Our central question is: How much freedom for personal development can we allow in the study of educational science and at the same time guarantee the quality of teacher training? It is our concern, both for us and for the students, to experience the changes that are necessary to help shape innovations in the educational system – in schools and in teacher training. Our approach as teachers and as scientists is to practice cooperation in research and teaching. The Aachen cooperation network is on the way. The “Denkkollektiv” [“thinking collective”], the “Aachener Bildungsgespräche” [“Aachen Education Talks”] and a number of cooperations with schools have already been realized. On the way ahead, we want to continue to experience change and help shape innovations together.
description: WE_OS Jahrbuch, Bd. 3 (2020): Kooperation von Universitäten und Schulen – Gründungsschrift des Verbunds Universitäts- und Versuchsschulen (VUVS)
Composite Designs Based on Orthogonal Arrays and Definitive Screening Designs
Creators: name: Yong-Dao Zhou
name: Hongquan Xu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: Hematology

description: Central composite designs are widely used in practice for factor screening and building response surface models. We study two classes of new composite designs. The first class consists of a two-level factorial design and a three-level orthogonal array; the second consists of a two-level factorial and a three-level definitive screening design. We derive bounds of their efficiencies for estimating all and part of the parameters in a second-order model and obtain some general theoretical results. New composite designs are constructed. They are more efficient than central composite designs and other existing designs. Supplementary materials are available online.
Returning to the Onyx Womb: Collective Identity vs. Extractivism of a Sacred Stone
Creators: name: Adhara Gaytan Cuesta, Andrea
Publisher: name: Humanities Commons
Year: 2024

description: Leobardo walks with his teared-up sandals into the mountain of Onyx Ambar, in Zapotitlán Salinas, Puebla, which is part of the Tehuacán-Cuicatlán Biosphere Reserve, a UNESCO-protected area since 2018. As an example of social mining, Leobardo works in precarity on community-owned land but takes part in the Mexican production of onyx marble. He shows his hand-made tunnels in the heart of the mountain, going in for more than 70 kilometers. Showing his lost three fingers, wounded in an explosive accident, he carves, finds the vein of onyx, and sings with his rustic chisel. In this article, I analyze the documentary The Return to the Onyx Womb (2021) as part of El Universo de Hefesto, a collective of short films made by the filmmaker Benjamín Alcántara, accessible online. I aim to explore the close entanglements between territory, ancient knowledge, and production of onyx, contrasting the classical concept of extractivism with social mining, and the ecocritical decolonial approach of “Sentipensar con la Tierra” (ThinkingFeeling with the land). I argue that Alcántara allows the viewer to experience the mountain and the mining activity by engaging the senses through his images and sounds of artisanal mining inside the hill. Hand-held camera shots, closeups, and contrasting movements provide a full-bodied experience, highlighting onyx as an important part of cultural heritage and visibilizing artisanal labor as part of a collective identity in contrast to the modern mining industry and its processes of automatization, acceleration, and accumulation of resources. Keywords: embodied cinemas, extractivism, onyx, Mexico, social mining.
Composite Designs Based on Orthogonal Arrays and Definitive Screening Designs
Creators: name: Yong-Dao Zhou
name: Hongquan Xu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: Hematology

description: Central composite designs are widely used in practice for factor screening and building response surface models. We study two classes of new composite designs. The first class consists of a 2-level factorial design and a 3-level orthogonal array; the second consists of a 2-level factorial and a 3-level definitive screening design. We derive bounds of their efficiencies for estimating all and part of the parameters in a second-order model and obtain some general theoretical results. New composite designs are constructed. They are more efficient than central composite designs and other existing designs. Supplementary materials are available online.
Bayesian Phase I/II Biomarker-based Dose Finding for Precision Medicine with Molecularly Targeted Agents
Creators: name: Beibei Guo
name: Yuan, Ying
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: The optimal dose for treating patients with a molecularly targeted agent may differ according to the patient's individual characteristics, such as biomarker status. In this article, we propose a Bayesian phase I/II dose-finding design to find the optimal dose that is personalized for each patient according to his/her biomarker status. To overcome the curse of dimensionality caused by the relatively large number of biomarkers and their interactions with the dose, we employ canonical partial least squares (CPLS) to extract a small number of components from the covariate matrix containing the dose, biomarkers, and dose-by-biomarker interactions. Using these components as the covariates, we model the ordinal toxicity and efficacy using the latent-variable approach. Our model accounts for important features of molecularly targeted agents. We quantify the desirability of the dose using a utility function and propose a two-stage dose-finding algorithm to find the personalized optimal dose according to each patient's individual biomarker profile. Simulation studies show that our proposed design has good operating characteristics, with a high probability of identifying the personalized optimal dose.
In Pursuit of the Faceless Stranger: Depths and Surfaces in Margaret Atwood’s Bodily Harm
Creators: name: Lucking, David
Publisher: name: Humanities Commons
Year: 1990
Subjects: subject: Canadian literature

description: Margaret Atwood's Bodily Harm is in one sense about the tension between surface perception and depth perception. Whatever is trivial and banal is easier and therefore preferable to Rennie, the novel's protaganist. As the novel progresses, she discovers the depths of both intimacy and depravity. The novel, ostensibly a conventional thriller, ultimately both utilizes and undermines the conventions of genre; indeed, there is a formal dialectical tension between the underlying structure of this author's works and the direction of moral implication in which those same works tend.
Improving Democracy: Public Debate, Listening, and National Conversations
Creators: name: Woodland, Miranda
Publisher: name: unknown
Year: 2024
Subjects: subject: Communication
subject: Democracy

description: This essay explores the vital components necessary for a thriving democracy, focusing on the importance of effective public discourse, active listening, and inclusive national conversations. Through an examination of Angus's analysis of public spaces, Welton's emphasis on listening, and Pearce's concept of a national conversation, the essay highlights the critical role of robust communication practices in democratic participation, particularly within online spaces. Angus argues that genuine democracy extends beyond electoral processes, emphasizing the need for accessible public spaces for debate, while critiquing modern media for limiting authentic public discourse. Welton underscores the importance of listening as a fundamental skill for democratic citizenship, advocating for educational initiatives to address power imbalances and enhance mutual understanding. Pearce, on the other hand, calls for a more interactive and inclusive national conversation that transcends the limitations of mass communication. Together, these perspectives underscore the necessity of fostering a culture of open dialogue, reflective listening, and meaningful engagement to strengthen democratic processes, particularly in the digital age. The essay also reflects on the challenges posed by contemporary media and social divisions, offering insights into how digital platforms can be leveraged to promote a healthier democratic discourse.
Improving Democracy: Public Debate, Listening, and National Conversations
Creators: name: Woodland, Miranda
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Democracy
subject: Communication

description: This essay explores the vital components necessary for a thriving democracy, focusing on the importance of effective public discourse, active listening, and inclusive national conversations. Through an examination of Angus's analysis of public spaces, Welton's emphasis on listening, and Pearce's concept of a national conversation, the essay highlights the critical role of robust communication practices in democratic participation, particularly within online spaces. Angus argues that genuine democracy extends beyond electoral processes, emphasizing the need for accessible public spaces for debate, while critiquing modern media for limiting authentic public discourse. Welton underscores the importance of listening as a fundamental skill for democratic citizenship, advocating for educational initiatives to address power imbalances and enhance mutual understanding. Pearce, on the other hand, calls for a more interactive and inclusive national conversation that transcends the limitations of mass communication. Together, these perspectives underscore the necessity of fostering a culture of open dialogue, reflective listening, and meaningful engagement to strengthen democratic processes, particularly in the digital age. The essay also reflects on the challenges posed by contemporary media and social divisions, offering insights into how digital platforms can be leveraged to promote a healthier democratic discourse.
The Erotic Phenomenon of Charlotte Smith’s “Flora”
Creators: name: Sigler, David
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Smith, Charlotte
subject: Botany in literature
subject: Romanticism
subject: Phenomenology
subject: Marion, Jean-Luc, 1946-

description: A discussion of eroticism in Charlotte Smith's botanical poem Flora, as considered in light of Jean-Luc Marion's concept of "the erotic phenomenon."
Network Reconstruction From High Dimensional Ordinary Differential Equations
Creators: name: Shizhe Chen
name: Shojaie, Ali
name: Witten, Daniela M.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: We consider the task of learning a dynamical system from high-dimensional time-course data. For instance, we might wish to estimate a gene regulatory network from gene expression data measured at discrete time points. We model the dynamical system non-parametrically as a system of additive ordinary differential equations. Most existing methods for parameter estimation in ordinary differential equations estimate the derivatives from noisy observations. This is known to be challenging and inefficient. We propose a novel approach that does not involve derivative estimation. We show that the proposed method can consistently recover the true network structure even in high dimensions, and we demonstrate empirical improvement over competing approaches.
Chip on the shoulder? The hunchback heuristic predicts the attribution of anger to low status groups and calm to high status groups
Creators: name: Rubin, Mark
Publisher: name: figshare
Year: 2016
Subjects: Personality, Social and Criminal Psychology

description: Across societies, there is a tendency to associate members of low status groups with anger, and to associate members of high status groups with calm (i.e. the hunchback heuristic), but there is no empirical documentation for this phenomenon. Thus, in a pilot study (N = 30) we validated the stimuli that we generated to test the existence of a hunchback stereotype by distinguishing two interstatus contexts of skinshade and race in terms of social status: Dark-skinned Indians (and Blacks) were perceived as lower in social status compared to light-skinned Indians (and Whites). Using a multi-method approach comprising an IAT-like protocol and explicit self-reports, Study 2 (N = 80) revealed that perceivers associated dark-skinned Indians with anger, and light-skinned Indians with calm: An effect that was explained by perceived social status. Study 3 (N = 114) corroborated the evidence from Study 2, but in the interstatus contexts of Blacks vs. Whites, and large men vs. slim men. Blacks (and large men) were associated with anger, and Whites (and slim men) were associated with calm. Additionally, Study 3 ruled out “racial prejudice” as an explanation for these trends. We conclude with an outline of the theoretical and practical implications of these findings.
Land wealth generation and distribution in the process of land expropriation and development in Beijing, China
Creators: name: Jinfeng Du
name: Thill, Jean-Claude
name: Changchun Feng
name: Guangyin Zhu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Based on transaction data at the parcel level in Beijing, this paper itemizes the costs incurred in the process of transferring rural land to urban development, quantifies the exact magnitude of land appreciation generated in this process and examines how the land wealth is distributed among involved parties. The main findings include the following: first, the land appreciation and the costs incurred in the process of land expropriation and primary development both differ from case to case; second, conventional comparison of the compensation for expropriated land with land granting price substantially overestimates the magnitude of land appreciation; the average and the median land appreciations account for 44.8% and 44.0% of the mean and median prices of granted serviced land, respectively; last, the compensation paid to affected farmers has improved in absolute terms during our study period from 2003 to 2014; however, because the land granting price has been escalating at a faster pace, the land wealth received by local governments has trended up.
Birds of the Patos Lagoon Estuary and adjacent coastal waters, southern Brazil: species assemblages and conservation implications
Creators: name: Dias, Rafael Antunes
name: Maurício, Giovanni Nachtigall
name: Bugoni, Leandro
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Estuarine avifauna is usually diverse, with marked differences along the limnetic to marine gradient and strong influences from physical factors such as salinity, habitat heterogeneity and tidal regime. Here we describe the composition of the avifauna of the Patos Lagoon Estuary and adjacent marine beaches and waters, in southern Brazil, identify the main environmental factors determining variations in species richness along the limnetic-marine gradient, evaluate changes in species composition along this gradient, and discuss the role of the estuary for bird conservation. Overall, 268 bird species were detected at eight sites along the estuary. Despite similar observed richness in spring–summer (247 species) and autumn–winter (244), there was a strong seasonal influence in bird composition due to migrants. Estimated species richness at 94% coverage of sites ranged from 9 to 194.66. Species richness decreased markedly towards the lower estuary, with the single variable ‘distance from the upper estuary’, accounting for the most plausible model. The number of threatened species recorded per site was larger in the lower estuary due the predominance of seabirds and shorebirds on red lists. While the lower estuary holds key feeding and roosting areas for seabirds and shorebirds, the upper estuary harbours more species, mainly forest passerines and waterbirds. Our findings confirm that estuarine gradients strongly influence avian diversity and highlight the importance of estuaries for the conservation of birds, especially migratory sea and shorebirds, and resident saltmarsh-dependent species.
The Russian-African Summit 2023: Prospects, Hopes, and Chances
Creators: name: Saaida, Mohammed
Publisher: name: Zenodo
Year: 2023
Subjects: subject: Russian-African Summit
subject: Chances
subject: Political economy
subject: Political transitions
subject: Political sciences
subject: Political communication
subject: Political policies
subject: Foreign policy
subject: Political philosophy

description: The Russian-African Summit in St. Petersburg in July 2023, an unprecedented event bringing together leaders from Russia and various African countries, holds immense significance in the realm of international relations. This summit, aimed at fostering cooperation and strengthening ties between Russia and Africa, has sparked both hopes and skepticism within the global community. With Africa's growing economic potential and Russia's strategic interests, the summit bears the potential to yield substantial benefits for both parties involved. This essay delves into the prospects, hopes, and chances of the Russian-African Summit, exploring its implications for regional and global dynamics.
Play, Learn, Excel: Gamification in ELN Training  with The Chemotion Files
Creators: name: Golub, Benjamin
Publisher: name: Zenodo
Year: 2024
Subjects: Gamification
Chemotion
electronic lab notebooks

description: This presentation was given at the NFDI4Chem Stammtisch on March 22nd, 2024. It focuses on the aspect of gamification to teach features of electronic lab notebooks, and why this can be useful. In addition to the published slides, a live demo of "The Chemotion Files" was part of the presentation. "The Chemotion Files" is an escape-room-like game, and was shown as an example. To check out "The Chemotion Files" see the related works on this upload.

The upload consists of two files. One is the actual presentation as a PDF file, the other one is a collection of the links given in the presentation.
Endangered Languages: Rescuing the World’s Invisible Libraries
Creators: name: Hu, Xinlan Emily
Publisher: name: Stanford Digital Repository
Year: 2024
Subjects: College students' writings, endangered language, language preservation

description: This essay won or received an honorable mention for The Boothe Prize for excellence in first-year writing. The Boothe Prize recognizes and rewards outstanding expository and argumentative writing by undergraduate students in first-year classes that satisfy the WR 1 requirement. In each award-winning essay, student writers demonstrate clarity of argument, excellent integration of research-based evidence, and compelling prose style.
This essay considers the unintended consequences that thwart many well-meaning attempts to preserve endangered languages. Comparing two case studies of efforts to preserve languages in China and in Mexico, the author argues that governments, linguists, and others who wish to preserve languages must do the ethical work of also preserving the dignity of the users of those languages.
Swiftaid Rodin Event-B models
Creators: name: Williams, David M.
name: Darwish, Salaheddin
name: Schneider, Steve
name: Michael, David R.
Publisher: name: Zenodo
Year: 2020
Subjects: Event-B
Rodin
Formal Model

description: This repository contains the formal Event-B models of the Swiftaid system for automated Gift Aid that were developed using the Rodin tool.
DURABILITY OF LAKATAN (MUSA ACUMINATA) PSEUDO-STEM AS A SUSTAINABLE SOURCE FOR PAPER PRODUCTION: A COMPARATIVE STUDY OF TENSILE STRENGTH, ABRASION, AND THICKNESS
Creators: name: Aguilar, Marjorie A.
name: Anselmo, Charlie T.
name: Boral, Jenna Mae B.
name: Corpuz, Reygime I.
name: Corpuz, Reygime I.
name: Ingente, Ma. Andrea G.
Publisher: name: Humanities Commons
Year: 2024

description: This study aimed to evaluate the durability of an alternative organic paper made from the lakatan (Musa acuminata) pseudostem as a sustainable source for paper production. The research was conducted at Isabela State University, Cauayan Campus. Three treatments were tested: commercial Manila paper made from 8 g, lakatan paper made from 5 g, and lakatan paper made from 3 g of pseudostem. The durability of the paper was assessed by tensile strength, abrasion, and thickness tests. The results revealed significant differences among the treatments. The 5 g lakatan pseudostem paper exhibited the highest tensile strength and abrasion resistance compared to the other treatments. Additionally, the 5 g lakatan pseudostem paper was thicker than the commercial Manila paper. These findings suggest that lakatan (Musa acuminata) pseudostem paper is durable and can be recommended as an alternative source of material for paper production. This study highlights the potential of utilizing banana pseudostem waste as a sustainable alternative to traditional paper production methods, which contributes to deforestation and air pollution. The use of the lakatan pseudostem for paper production could help reduce the environmental impact of the paper industry, while providing valuable use for agricultural waste.
Analysis on Data Governance Policy in the Health Sector of Zambia: Perspective of Big Data
Creators: name: Chikwanda, Kampamba
name: Daka, Steven
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Big data
subject: Data protection

description: The study explored the data governance policy in Zambia's health sector, focusing on big data. To fully realize the potential of data in our digital age, proper data governance is required. However, questions have been expressed concerning Zambia's health sector's ability to exploit data as a valuable resource due to the state of data governance. This study attempts to address this critical issue and shed light on the functions of big data governance aspects in the health sector. This work is significant because it has the potential to improve healthcare service quality, decision-making, and resource allocation through strong data governance. This study aims to bridge the gap between data governance and the requirements of big data in the Zambian health sector by reviewing existing policies, procedures, and practices. A mixed methods approach is used in the research, involving qualitative interviews with key informants and secondary data analysis. To get a full understanding of data governance difficulties, practices, and their alignment with big data demands, thematic and content analysis methodologies were used. The findings show that data governance is critical to managing data in the health sector, yet gaps in governance procedures impede the efficient implementation of ICT efforts. These concerns are exacerbated by challenges relating to competent human resources and ICT infrastructure. Accountability and transparency are also identified as areas for improvement. While this study offers insight on the existing state of affairs, it recognizes its limits and advocates for further research to investigate specific aspects of policy implementation. Nonetheless, this study contributes significantly to the field of big data and data governance in the Zambian health sector, encouraging stakeholders to work for an ICT driven, data-governed future that promotes openness, accountability, and improved healthcare results.
3R’S EVERY HOUR: UNMASKING THE VIEWS OF SENIOR HIGH SCHOOL STUDENTS TOWARDS PROPER WASTE MANAGEMENT
Creators: name: Balingit, Mark Andrei
name: Canlas, Jermineryn
name: De Jesus, Emelita
name: Dela Cruz, Diana Roxette
name: Dela Cruz, Diana Roxette
name: Jaque, Aaliyah Robin
name: Liam, Kathrina Irish
name: Liwanag, John Abraham
name: Marcaida, John Louise
name: Membrado, Tyron Jay
name: Perez, Carlo Don Daz
Publisher: name: Humanities Commons
Year: 2024

description: This study was geared to unmask the views of senior high school students towards proper waste management in a private institution in Pampanga, Philippines. The researchers interviewed 30 senior high school students who voluntarily participated by responding to an open-ended questionnaire. The findings of the open-ended questionnaire deciphered the views of the senior high school students towards proper waste management. This study utilized Braun and Clarke's Thematic analysis. The study revealed five emerging themes that described the views of the senior high school students towards proper waste management, namely: (1) Trash Breaks: Applying Intervals to Classroom Cleanup. (2) Inconsistent Commitment to Continuous Workplace Cleanliness. (3) Disciplinary Measures and Academic Consequences of Inadequate Trash Disposal. (4) Promoting responsible waste management and environmental initiatives (5) Educational Engagement and Behavior Adjustment About Proper Waste Management. The findings offer actionable insights for private institutions, recommending the initiation of eco-friendly programs and educational workshops to improve waste management practices.