cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Der Pessimismus des Verstands und der Optimismus des Willens
Creators: name: Srubar, Ilja
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Wer sich ins Reich der Werte begibt, bewegt sich auf unsicherem Boden. Denn eine Sache ist es, dieses Reich quasi von außen als einen Gegenstand der Analyse zu betrachten, und eine andere, die Genese der Werte, ihrer Geltung sowie der möglichen Universalisierung ihrer Inhalte zu ergründen. Im ersten Falle ist es ein relativ Leichtes, zu zeigen, dass es irgendwelche Werte und Moralen überall und immer gibt, dass man sie so als eine anthropologische Universalie ansehen kann, deren integrative bzw. polemogene Funktionen empirisch erfasst und beschrieben werden können. Man kann sich zwar immer noch streiten, ob die Genese der Moralen und Werte eher in interaktiven oder in (nur) kommunikativen Prozessen liegt, wie auch darüber, worauf den genau ihre Institutionalisierung, Überlieferung bzw. ihr Wandel zurückzuführen sind, aber im Großen und Ganzen steht der Soziologe hier – spätestens seit Parsons – vor keinem großen Geheimnis, von einem Tremendum gar zu schweigen.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Die Sakralität der Person oder Können Kollektive konvertieren?
Creators: name: Wohlrab-Sahr, Monika
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Hans Joas hat mit seinem Buch »Die Sakralität der Person« einen neuen Baustein zu etwas hinzugefügt, das sich – im Wortsinn – zunehmend als »Werk« darstellt. Eine zum Teil aufeinander aufbauende, zum Teil sich im Nachhinein zusammenfügende Folge von Schriften, die an einer Stelle aufgeworfene Fragen an einer anderen Stelle zu beantworten suchen, die sich wechselseitig kommentieren, ergänzen, bestätigen, aber auch manche frühere Vereinseitigung zurechtrücken. Erkennbar wird hier ein Weiterschreiben, Weiterdenken an einer Linie, die von »Die Kreativität des Handelns« über »Die Entstehung der Werte«, »Das Leben als Gabe«, »Kriege und Werte«, »Braucht der Mensch Religion?« bis hin zum neuesten Buch über »Die Sakralität der Person« führt.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Yip Sing, Lorna Yip, Chong Fow, Mah Fong, Yuey Chong, Gow Leong Ton, Lew Hung, Lee Chong Moon, Lee Nin Non, Wong On.
Die Erfahrung der Menschenwürde und ihre Grenzen
Creators: name: Adloff, Frank
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Hans Joas hat sich mit »Die Sakralität der Person« zum Ziel gesetzt, eine alternative Geschichte der Menschenrechte und ihrer Begründung zu liefern. Die Kluft zwischen Philosophie und Geschichtswissenschaft soll mittels eines Aufeinanderbeziehens der Begründungsargumente und der historischen Reflexion überwunden werden. Dieses Projekt belegt Joas mit dem Begriff der affirmativen Genealogie. Es geht nicht um eine rationale Begründung der Menschenrechte als letzte Werte, sondern die verknüpfende Erzählung der Entstehung und Ausbreitung mit ihrer Begründung wird angestrebt. Die Bindungen an Werte beruhen auf spezifischen, historisch rekonstruierbaren Erfahrungen, das heißt, sie sind kontingent, doch daraus folgt für Joas nicht, dass ihre Evidenz fragwürdig wird – ganz im Gegenteil. Joas formuliert damit eine klar konturierte und fundamentale Alternative zu rationalistischen Begründungen der Menschenrechte, wie sie Habermas oder Rawls vertreten, ohne dabei in einen historistischen Relativismus zu verfallen.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Eng Ghim Hong, Jang Yen Him, Chow Yue Luk, Lew Heam, Chin Ah Foon, Fong Lee Chu, Leong Tai Sun, Lew Man Sing, Lee Jack, Ching Yuen.
Flows of water on a nineteenth-century Australian goldfield
Creators: name: Davies, Peter
name: Lawrence, Susan
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 37
subject: Earth sciences
classificationCode: 3707
subject: Hydrology
classificationCode: 44
subject: Human society
classificationCode: 4406
subject: Human geography

description: No description supplied.
Flows of water on a nineteenth-century Australian goldfield
Creators: name: PW Davies
name: S Lawrence
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: The goldrush in Victoria during the 1850s and 1860s created new awareness of the many meanings and values of water. Most mining technologies required substantialquantities of water to power machinery and separate gold from the earth, but available supplies were often inadequate. Miners responded by constructing dams and lengthy races to capture, store and distribute water to mining claims. In the process they created extensive landscapes of water management, where the natural flow of water was layered with industrial, legal, commercial and social flows as well. Experience in water manipulation on the Victorian goldfields played an important role in the later development of water laws and state water management.
Dimerization of Bacterial Diaminopimelate Decarboxylase Is Essential for Catalysis
Creators: name: Peverelli, MG
name: Soares-da-Costa, Tatiana
name: Kirby, N
name: Perugini, Matthew
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences

description: Diaminopimelate decarboxylase (DAPDC) catalyzes the final step in the diaminopimelate biosynthesis pathway of bacteria. The product of the reaction is the essential amino acid L-lysine, which is an important precursor for the synthesis of the peptidoglycan cell wall, housekeeping proteins, and virulence factors of bacteria. Accordingly, the enzymeisapromising antibacterial target. Previous structural studies demonstrate that DAPDC exists as monomers, dimers, and tetramers in the crystal state. However, the active oligomeric form has not yet been determined. We show using analytical ultracentrifugation, small angle x-ray scattering, and enzyme kinetic analyses in solution that the active form of DAPDC from Bacillus anthracis, Escherichia coli, Mycobacterium tuberculosis, and Vibrio cholerae is a dimer. The importance of dimerization was probed further by generating dimerization interface mutants (N381A and R385A) of V. cholerae DAPDC. Our studies indicate that N381A and R385A are significantly attenuated in catalytic activity, thus confirming that dimerization of DAPDC is essential for function. These findings provide scope for the development of new antibacterial agents that prevent DAPDC dimerization.
From discrete integrable equations to Laurent recurrences
Creators: name: Hamad, Khaled
name: Van Der Kamp, Pieter
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 49
subject: Mathematical sciences
classificationCode: 4901
subject: Applied mathematics
classificationCode: 4904
subject: Pure mathematics

description: We show how to obtain relations for the divisors of terms generated by a homogenized version of a rational recurrence. When the rational recurrence confines singularities the relations take the form of a rational recurrence, possibly with periodic coefficients. As the recurrence generates polynomials one expects it to possess the Laurent property. The method we develop uses ultra-discretization and recursive factorization. It is applied to certain QRT-maps which gives rise to Somos-k (k = 4, 5) sequences with periodic coefficients. Novel (N + 3)-rd order recurrences are obtained from the Nth order DTKQ-equation (N = 2, 3). In each case the resulting recurrence equation has the Laurent property. The method is equally applicable to non-integrable or non-confining equations. However, in the latter case the degree and the order of the relation might display unbounded growth. We demonstrate the difference, by considering different parameter choices in a generalized Lyness equation.
From discrete integrable equations to Laurent recurrences
Creators: name: Hamad, Khaled
name: Van Der Kamp, Pieter
Publisher: name: La Trobe
Year: 2022

description: We show how to obtain relations for the divisors of terms generated by a homogenized version of a rational recurrence. When the rational recurrence confines singularities the relations take the form of a rational recurrence, possibly with periodic coefficients. As the recurrence generates polynomials one expects it to possess the Laurent property. The method we develop uses ultra-discretization and recursive factorization. It is applied to certain QRT-maps which gives rise to Somos-k (k = 4, 5) sequences with periodic coefficients. Novel (N + 3)-rd order recurrences are obtained from the Nth order DTKQ-equation (N = 2, 3). In each case the resulting recurrence equation has the Laurent property. The method is equally applicable to non-integrable or non-confining equations. However, in the latter case the degree and the order of the relation might display unbounded growth. We demonstrate the difference, by considering different parameter choices in a generalized Lyness equation.
Supplementary document for Strong Interlayer Coupling in p-Te/n-CdSe van der Waals Heterojunction for Self-Powered Photodetectors with Fast Speed and High Responsivity - 6432697.pdf
Creators: name: Hu, Yanjie
name: Song, Xiaohui
name: Jia, Dongliang
name: Su, Wanhan
name: Lv, Xiaojing
name: Li, Lin
name: Li, Xueping
name: Yan, Yong
name: Jiang, Yurong
name: Xia, Congxin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1 for device fabrication, material characterization,Ids-Vds curves,photocurrent response,Table 1
Replik
Creators: name: Joas, Hans
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Mein Buch von 2011 zur Geschichte und Begründung der Menschenrechte hat nicht nur in der breiteren Öffentlichkeit, sondern auch in einer ganzen Reihe von akademischen Fächern – Jurisprudenz und Geschichte, Philosophie und Theologie – ein für mich erfreulich lebhaftes Interesse gefunden. Zur Lebhaftigkeit gehört, dass viele meiner Thesen und meine Vorgehensweise insgesamt auch durchaus kontrovers beurteilt werden. Manchmal hat das öffentliche oder das interdisziplinäre Interesse an einem Buch jedoch paradoxerweise zur Kehrseite, dass das eigene Fach mit Fremdheitsgefühlen reagiert. Es ist für mich deshalb besonders wichtig, dass sich diese noch junge Zeitschrift und mehrere renommierte Vertreter meines eigenen Faches zu einer so breiten und gründlichen Auseinandersetzung mit der »Sakralität der Person« entschieden haben.1 Das Angebot, auf diese kritischen Darlegungen zu reagieren, nehme ich deshalb dankbar und gerne an.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
K. Brad Wray (2011): Kuhn’s Evolutionary Social Epistemology
Creators: name: Seidel, Markus
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Ni hon eus eur c'hogik yaouank
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2024

Abstract
Die Herausforderung des impliziten Wissens für die theoretische Soziologie
Creators: name: Gubo, Michael
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Wong Sik Quon, Quon Gow, Quan Mary, Quan Ben Dick, Quan Mon Dick, Joe Man Sum, Lee San Y, Lee Chuang, Chin Ming Shek, Yip Sar Quon, Lew Lett Nine, Lai Mow, Chin Yuen Bing.
Robert Schmidt (2012): Soziologie der Praktiken. Konzeptionelle Studien und Empirische Analysen
Creators: name: Bochmann, Annett
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Emphysematous pancreatitis
Creators: name: Navarro BaÃ±O, Antonio
Publisher: name: EURORAD
Year: 2016
Subjects: subject: Abdomen
subject: CT
subject: Surgery
subject: Acute

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 68 years
description: Clinical History: A 68 years-old man without known allergies. No DM. No arterial hypertension. Non-smoker. Isquemic stroke 11 years ago. Peptic esophagitis. No surgical history of interest. In the last year an ultrasound and gastroscopy was performed without pathological f... Final Diagnosis: Emphysematous pancreatitis.
Appendiceal metastatic neuroendocrine tumor
Creators: name: Sousa, Marta
Publisher: name: EURORAD
Year: 2016
Subjects: subject: Abdomen
subject: Cardiovascular system
subject: Gastrointestinal tract
subject: CT
subject: MR
subject: Nuclear medicine conventional
subject: Diagnostic procedure
subject: Metastases
subject: Neoplasia

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 62 years
description: Clinical History: A 62 year old man was admitted in the emergency room for right quadrant abdominal pain. He was under diagnostic investigation for cardiac failure in our institution. The patient also referred few months lasting diarrhea and flushing. Final Diagnosis: Appendiceal carcinoid with mesenteric and liver metastasis, associated with carcinoid syndrome.
Molecular and structural characterization of a novel Escherichia coli interleukin receptor mimic protein
Creators: name: Moriel, DG
name: Heras, Begona
name: Paxman, Jason
name: Lo, AW
name: Tan, L
name: Sullivan, MJ
name: Dando, SJ
name: Beatson, SA
name: Ulett, GC
name: Schembri, MA
Publisher: name: La Trobe
Year: 2023

description: Urinary tract infection (UTI) is a disease of extremely high incidence in both community and nosocomial settings. UTIs cause significant morbidity and mortality, with approximately 150 million cases globally per year. Uropathogenic Escherichia coli (UPEC) is the primary cause of UTI and is generally treated empirically. However, the rapidly increasing incidence of UTIs caused by multidrug-resistant UPEC strains has led to limited available treatment options and highlights the urgent need to develop alternative treatment and prevention strategies. In this study, we performed a comprehensive analysis to define the regulation, structure, function, and immunogenicity of recently identified UPEC vaccine candidate C1275 (here referred to as IrmA). We showed that the irmA gene is highly prevalent in UPEC, is cotranscribed with the biofilm-associated antigen 43 gene, and is regulated by the global oxidative stress response OxyR protein. Localization studies identified IrmA in the UPEC culture supernatant. We determined the structure of IrmA and showed that it adopts a unique domain-swapped dimer architecture. The dimeric structure of IrmA displays similarity to those of human cytokine receptors, including the interleukin-2 receptor (IL-2R), interleukin-4 receptor (IL-4R), and interleukin-10 receptor (IL-10R) binding domains, and we showed that purified IrmA can bind to their cognate cytokines. Finally, we showed that plasma from convalescent urosepsis patients contains high IrmA antibody titers, demonstrating the strong immunogenicity of IrmA. Taken together, our results indicate that IrmA may play an important role during UPEC infection.IMPORTANCE Uropathogenic E. coli (UPEC) is the primary cause of urinary tract infection (UTI), a disease of major significance to human health. Globally, the incidence of UPEC-mediated UTI is strongly associated with increasing antibiotic resistance, making this extremely common infection a major public health concern. In this report, we describe the regulatory, structural, functional, and immunogenic properties of a candidate UPEC vaccine antigen, IrmA. We demonstrate that IrmA is a small UPEC protein that forms a unique domain-swapped dimer with structural mimicry to several human cytokine receptors. We also show that IrmA binds to IL-2, IL-4, and IL-10, is strongly immunogenic in urosepsis patients, and is coexpressed with factors associated with biofilm formation. Overall, this work suggests a potential novel contribution for IrmA in UPEC infection.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Chin Fong, Jung Hem Yick, Leong Jack Wing, Sam Shee, Lee Gip Choon, Chou You, Lee Gim, Toy Yuen Chow, Sam Marr, Lim Sin Art.
»Ist Gesellschaft ein soziologisch gehaltvoller Begriff?«
Creators: name: Korte, Jasper W.
name: Gubo, Michael
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Dynamic Modelling Reveals 'Hotspots' on the Pathway to Enzyme-Substrate Complex Formation
Creators: name: Gordon, Shane
name: Weber, DK
name: Downton, MT
name: Wagner, J
name: Perugini, Matthew
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 310106
subject: Enzymes

description: Dihydrodipicolinate synthase (DHDPS) catalyzes the first committed step in the diaminopimelate pathway of bacteria, yielding amino acids required for cell wall and protein biosyntheses. The essentiality of the enzyme to bacteria, coupled with its absence in humans, validates DHDPS as an antibacterial drug target. Conventional drug design efforts have thus far been unsuccessful in identifying potent DHDPS inhibitors. Here, we make use of contemporary molecular dynamics simulation and Markov state models to explore the interactions between DHDPS from the human pathogen Staphylococcus aureus and its cognate substrate, pyruvate. Our simulations recover the crystallographic DHDPS-pyruvate complex without a priori knowledge of the final bound structure. The highly conserved residue Arg140 was found to have a pivotal role in coordinating the entry of pyruvate into the active site from bulk solvent, consistent with previous kinetic reports, indicating an indirect role for the residue in DHDPS catalysis. A metastable binding intermediate characterized by multiple points of intermolecular interaction between pyruvate and key DHDPS residue Arg140 was found to be a highly conserved feature of the binding trajectory when comparing alternative binding pathways. By means of umbrella sampling we show that these binding intermediates are thermodynamically metastable, consistent with both the available experimental data and the substrate binding model presented in this study. Our results provide insight into an important enzyme-substrate interaction in atomistic detail that offers the potential to be exploited for the discovery of more effective DHDPS inhibitors and, in a broader sense, dynamic protein-drug interactions.
Adapting Business Models to Support Human Right for All—The 2024 A4S International Case Competition
Creators: name: Donovan, Claire
Publisher: name: University of Notre Dame
Year: 2025
Subjects: classificationCode: 41
subject: Environmental sciences

description: The A4S International Case Competition (A4SICC) challenges students to develop sustainable business models that align profits with human rights. Since 2018, A4SICC has provided a platform for graduate and undergraduate students to tackle global sustainability challenges. The 2024 theme focused on adapting business models to support human rights. The competition fosters networking, mentorship, and practical experience, empowering future professionals to drive sustainable change in the business world.
»Kritische Soziologie meets Critical Realism. A Dialogue between Social Research, Social Theory and Philosophy of Science.«
Creators: name: Sparsam, Jan
name: Hornei, Inga
name: Haubner, Tine
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 2 (2013): Soziologische Erklärung & Explanative Soziologie
Ancient mitochondrial DNA provides high-resolution time scale of the peopling of the Americas
Creators: name: Llamas, B
name: Fehren-Schmitz, L
name: Valverde, G
name: Soubrier, J
name: Mallick, S
name: Rohland, N
name: Nordenfelt, S
name: Valdiosera, Cristina
name: Richards, SM
name: Rohrlach, A
name: Romero, MI Barreto
name: Espinoza, I Flores
name: Cagigao, E Tomasto
name: Jimenez, L Watson
name: Makowski, K
name: Reyna, IS Leboreiro
name: Lory, J Mansilla
name: Torrez, JA Ballivian
name: Rivera, MA
name: Burger, RL
name: Ceruti, M Constanza
name: Reinhard, J
name: Wells, RS
name: Politis, G
name: Santoro, CM
name: Standen, VG
name: Smith, Colin
name: Reich, D
name: Ho, SYW
name: Cooper, A
name: Haak, W
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics
classificationCode: 430101
subject: Archaeological science
classificationCode: 44
subject: Human society
classificationCode: 4401
subject: Anthropology
subject: FOS: Sociology

description: The exact timing, route, and process of the initial peopling of the Americas remains uncertain despite much research. Archaeological evidence indicates the presence of humans as far as southern Chile by 14.6 thousand years ago (ka), shortly after the Pleistocene ice sheets blocking access from eastern Beringia began to retreat. Genetic estimates of the timing and route of entry have been constrained by the lack of suitable calibration points and low genetic diversity of Native Americans. We sequenced 92wholemitochondrial genomes from pre-Columbian South American skeletons dating from 8.6 to 0.5 ka, allowing a detailed, temporally calibrated reconstruction of the peopling of the Americas in a Bayesian coalescent analysis. The data suggest that a small population entered the Americas via a coastal route around 16.0 ka, following previous isolation in eastern Beringia for ∼2.4 to 9 thousand years after separation from eastern Siberian populations. Following a rapid movement throughout the Americas, limited gene flow in South America resulted in a marked phylogeographic structure of populations, which persisted through time. All of the ancient mitochondrial lineages detected in this study were absent from modern data sets, suggesting a high extinction rate. To investigate this further, we applied a novel principal components multiple logistic regression test to Bayesian serial coalescent simulations. The analysis supported a scenario in which European colonization caused a substantial loss of pre-Columbian lineages.
Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner
Creators: name: Polanco, JC
name: Scicluna, Benjamin J
name: Hill, Andrew
name: Gotz, J
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 310108
subject: Protein trafficking
classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences

description: The microtubule-associated protein tau has a critical role in Alzheimer disease and related tauopathies. There is accumulating evidence that tau aggregates spread and replicate in a prion-like manner, with the uptake of pathological tau seeds causing misfolding and aggregation of monomeric tau in recipient cells. Here we focused on small extracellular vesicles enriched for exosomes that were isolated from the brains of tau transgenic rTg4510 and control mice. We found that these extracellular vesicles contained tau, although the levels were significantly higher in transgenic mice that have a pronounced tau pathology. Tau in the vesicles was differentially phosphorylated, although to a lower degree than in the brain cells from which they were derived. Several phospho-epitopes (AT8, AT100, and AT180) thought to be critical for tau pathology were undetected in extracellular vesicles. Despite this, when assayed with FRET tau biosensor cells, extracellular vesicles derived from transgenic mice were capable of seeding tau aggregation in a threshold-dependent manner. We also observed that the dye used to label extracellular vesicle membranes was still present during nucleation and formation of tau inclusions, suggesting either a role for membranes in the seeding or in the process of degradation. Together, we clearly demonstrate that extracellular vesicles can transmit tau pathology. This indicates a role for extracellular vesicles in the transmission and spreading of tau pathology. The characteristics of tau in extracellular vesicles and the seeding threshold we identified may explain why tau pathology develops very slowly in neurodegenerative diseases such as Alzheimer disease.
title: Is it corruption? An institutional logic approach to corruption study in Thailand
Creators: name: Pumarin, Jiratdet
Publisher: name: University of Reading
Year: 2024

description: Corruption is a universal problem, and one that is extremely difficult to eradicate. In 
Thailand, corruption is rife, and despite various policy attempts by Thai government, there 
remains no solution for alleviating this issue. The aim of this thesis is to understand the meaning 
of corruption in Thai context and to recommend an appropriate plan that is suitable within that 
context. 
20 unstructured interviews were conducted on Thai business owners who shared their 
lived experience of corruption, with an institutional logic perspective applied as the method of 
analysis. The findings show that there are two prevalent justifications of corruption. First, 
corruption get things done. Second, corruption is an act of caring. This study shows that 
corruption holds different meanings in different contexts, and that to solve corruption, a 
specific anti-corruption campaign, suitable to the aforementioned contexts, is required. 
This approach helps examine the underlying principles and mechanisms through which 
corruption becomes normalised. In addition, it also challenges the perception that corruption is 
practised solely to maximise self-interest by showing that corruption, especially bribery, is not 
exclusively done out of pure self-interest, but also out of empathy, gratitude, and responsibility 
for one’s well-being.
Versuch eines »Kompositionistischen Manifests«
Creators: name: Latour, Bruno
name: Schölzel, Hagen
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Während Leute wie James Lovelock argumentierten, dass die menschliche Zivilisation durch »Gaias Rache« in ihrer Existenz bedroht sei (...), schaffte es die größte Zusammenkunft von Repräsentanten der Menschheit, tagelang herumzusitzen, ohne etwas zu tun oder die geringste Entscheidung zu treffen. Wem sollen wir glauben? Denen, die den Klimawandel als lebensbedrohliches Ereignis bezeichnen? Denen, die so tun als sei er ein gewöhnliches Ereignis und ohne großen Aufwand zu beherrschen? Oder denen, die meinen, der Fort-schritt solle weitergehen, was auch immer geschehe?
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 1 (2013): Science & Fiction
Physiotherapy for cystic fibrosis in Australia and New Zealand: a clinical practice guideline
Creators: name: Button, BM
name: Wilson, C
name: Dentice, R
name: Cox, Narelle
name: Middleton, A
name: Tannenbaum, E
name: Bishop, J
name: Cobb, R
name: Burton, K
name: Wood, M
name: Moran, F
name: Black, R
name: Bowen, S
name: Day, R
name: Depiazzi, J
name: Doiron, K
name: Doumit, M
name: Dwyer, T
name: Elliot, A
name: Fuller, L
name: Hall, K
name: Hutchins, M
name: Kerr, M
name: Lee, AL
name: Mans, C
name: O'Connor, L
name: Steward, R
name: Potter, A
name: Rasekaba, Tshepo
name: Scoones, R
name: Tarrant, Benjamin
name: Ward, Nathan
name: West, S
name: White, D
name: Wilson, L
name: Wood, J
name: Holland, Anne
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 420106
subject: Physiotherapy

description: Physiotherapy management is a key element of care for people with cystic fibrosis (CF) throughout the lifespan. Although considerable evidence exists to support physiotherapy management of CF, there is documented variation in practice. The aim of this guideline is to optimize the physiotherapy management of people with CF in Australia and New Zealand. A systematic review of the literature in key areas of physiotherapy practice for CF was undertaken. Recommendations were formulated based on National Health and Medical Research Council (Australia) guidelines and considered the quality, quantity and level of the evidence; the consistency of the body of evidence; the likely clinical impact; and applicability to physiotherapy practice in Australia and New Zealand. A total of 30 recommendations were made for airway clearance therapy, inhalation therapy, exercise assessment and training, musculoskeletal management, management of urinary incontinence, managing the newly diagnosed patient with CF, delivery of non-invasive ventilation, and physiotherapy management before and after lung transplantation. These recommendations can be used to underpin the provision of evidence-based physiotherapy care to people with CF in Australia and New Zealand.
title: Constructing localised pedagogies in Chinese literacy development: CFL teachers' pedagogical beliefs and classroom practices in Scottish secondary schools
Creators: name: Zhang, Leijun
Publisher: name: The University of Edinburgh
Year: 2025
Subjects: subject: Mandarin Chinese
subject: Chinese as a foreign language
subject: Scottish school curriculum
subject: Chinese literacy instruction
subject: linguistic skills
subject: (inter)cultural awareness
subject: global citizenship education
subject: CFL

description: The increasing global popularity of Mandarin Chinese and growing interest in learning Chinese as a foreign language (CFL) has resulted in Chinese becoming a newly emergent global language. In the context of the ScoQsh formal schooling system, Mandarin Chinese has been introduced as one of the school curriculum’s modern languages under the ScoQsh government’s ‘1+2’ languages iniVaVve. This study provides a nuanced understanding of the pedagogical beliefs of twelve CFL teachers regarding CFL literacy development and examines their classroom pracVces in ScoQsh secondary schools. Through interviews and classroom observaVons, the study found that the teachers’ personal learning histories in literacy and their status as Chinese L1 speakers were largely responsible for many of the beliefs they held about Chinese literacy instrucVon, such as the clear emphasis on linguisVc skills. The findings showed that the teachers felt the need to move away from their deeply rooted Chinese lived pedagogies and reassess their own orientaVons to Chinese literacy instrucVon in order to reposiVon Chinese literacy development in a way that is more relevant to their situated contexts. Challenges and opportuniVes in teaching linguisVcally and culturally diverse CFL learners in Scotland, such as developing pupils (inter)cultural awareness, are framed against the new demands of educaVon for global ciVzenship. Building on the findings, the study concludes with a set of implicaVons for the sustainable development of CFL educaVon based on localised pedagogies that relate to CFL teachers, professional networks or communiVes of pracVce and teacher educaVon, before offering recommendaVons for future research into the emerging field of CFL literacy development.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Coa Ki, Chow Doo Chew, Wong Bark Quon, Jang Fook Chee, Lee Wo Ling, Wong Shew Fon, Hong Goon Lew, Low Hee Young, Luey Yee Mon, Eng Hawk Tong, Lee May Gim, Eng King Ching, Eng Choy Yow.
Where are the missing practices? Bruno Latours experimentale Metaphysik
Creators: name: Holzinger, Markus
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Der Begriff Praxis avancierte in der Philosophie und Gegenwartssoziologie nach dem »pragmatic turn« zu einem paradigmatischen Schlüsselbegriff, um soziale Beziehungen und die damit zusammenhängende Entstehung sozialer Ordnung zu verstehen. Betrachtet man jedoch einige Praxistheorien genauer, so fällt auf, dass den zentralen pragmatischen Ansätzen häufig ein essentielles Element fehlt: nämlich Praktiken. Zumindest bleibt die Praxis als fundierendes Ereignis in seiner systematischen Relevanz für die Theoriebildung unklar. Ziel des vorliegenden Beitrages ist es, zu zeigen, dass und wie sich das Kernanliegen der Praxistheorie im Rahmen von Bruno Latours Akteur-Netzwerk-Theorie präziser zur Geltung bringen lässt als in anderen geläufigen Praxistheorien. Latours zentraler Gedanke ist, dass alles, was die Soziologie über die Wirklichkeit der Alltagswelt wissen kann, über den Weg des Explizitmachens der faktischen Gepflogenheiten in tatsächlich bestehenden Situationskontexten zurückgeführt werden muss (Ludwig Wittgenstein). Der Aufsatz erkundet die heuristischen Potentiale von Latours Forschungsprogramm und versucht aufzuzeigen, welche Konsequenzen daraus für die soziologische Theoriebildung gezogen werden müssen.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 1 (2013): Science & Fiction
title: Effects of geometric individualisation of a human spine model on load sharing : neuro-musculoskeletal simulation reveals significant differences in ligament and muscle contribution
Creators: name: Meszaros-Beller, Laura
name: Hammer, Maria
name: Riede, Julia M.
name: Pivonka, Peter
name: Little, J. Paige
name: Schmitt, Syn
Publisher: name: Universität Stuttgart
Year: 2023
Subjects: subject: 620
subject: 610

description: In spine research, two possibilities to generate models exist: generic (population-based) models representing the average human and subject-specific representations of individuals. Despite the increasing interest in subject specificity, individualisation of spine models remains challenging. Neuro-musculoskeletal (NMS) models enable the analysis and prediction of dynamic motions by incorporating active muscles attaching to bones that are connected using articulating joints under the assumption of rigid body dynamics. In this study, we used forward-dynamic simulations to compare a generic NMS multibody model of the thoracolumbar spine including fully articulated vertebrae, detailed musculature, passive ligaments and linear intervertebral disc (IVD) models with an individualised model to assess the contribution of individual biological structures. Individualisation was achieved by integrating skeletal geometry from computed tomography and custom-selected muscle and ligament paths. Both models underwent a gravitational settling process and a forward flexion-to-extension movement. The model-specific load distribution in an equilibrated upright position and local stiffness in the L4/5 functional spinal unit (FSU) is compared. Load sharing between occurring internal forces generated by individual biological structures and their contribution to the FSU stiffness was computed. The main finding of our simulations is an apparent shift in load sharing with individualisation from an equally distributed element contribution of IVD, ligaments and muscles in the generic spine model to a predominant muscle contribution in the individualised model depending on the analysed spine level.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Yee Hon, Mark Tong, Dong Sai Yuey, Chan Ah Foon, Jim Guey, Jim Jung Fat, Mah Yuen Kee, Mah Lin, Mah Hung Big, Mah Hung King.
title: Evaluation of gravitational curvatures for a tesseroid and spherical shell with arbitrary-order polynomial density
Creators: name: Deng, Xiao-Le
Publisher: name: Universität Stuttgart
Year: 2023
Subjects: subject: 624

description: In recent years, there are research trends from constant to variable density and low-order to high-order gravitational potential gradients in gravity field modeling. Under the research circumstances, this paper focuses on the variable density model for gravitational curvatures (or gravity curvatures, third-order derivatives of gravitational potential) of a tesseroid and spherical shell in the spatial domain of gravity field modeling. In this contribution, the general formula of the gravitational curvatures of a tesseroid with arbitrary-order polynomial density is derived. The general expressions for gravitational effects up to the gravitational curvatures of a spherical shell with arbitrary-order polynomial density are derived when the computation point is located above, inside, and below the spherical shell. When the computation point is located above the spherical shell, the general expressions for the mass of a spherical shell and the relation between the radial gravitational effects up to arbitrary-order and the mass of a spherical shell with arbitrary-order polynomial density are derived. The influence of the computation point’s height and latitude on gravitational curvatures with the polynomial density up to fourth-order is numerically investigated using tesseroids to discretize a spherical shell. Numerical results reveal that the near-zone problem exists for the fourth-order polynomial density of the gravitational curvatures, i.e., relative errors in log10scale of gravitational curvatures are large than 0 below the height of about 50 km by a grid size of 15′×15′. The polar-singularity problem does not occur for the gravitational curvatures with polynomial density up to fourth-order because of the Cartesian integral kernels of the tesseroid. The density variation can be revealed in the absolute errors as the superposition effects of Laplace parameters of gravitational curvatures other than the relative errors. The derived expressions are examples of the high-order gravitational potential gradients of the mass body with variable density in the spatial domain, which will provide the theoretical basis for future applications of gravity field modeling in geodesy and geophysics.
CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia
Creators: name: Williams, KL
name: Topp, S
name: Yang, S
name: Smith, B
name: Fifita, JA
name: Warraich, ST
name: Zhang, KY
name: Farrawell, N
name: Vance, C
name: Hu, X
name: Chesi, A
name: Leblond, CS
name: Lee, A
name: Rayner, SL
name: Sundaramoorthy, V
name: Dobson-Stone, C
name: Molloy, MP
name: van Blitterswijk, M
name: Dickson, DW
name: Petersen, RC
name: Graff-Radford, NR
name: Boeve, BF
name: Murray, ME
name: Pottier, C
name: Don, E
name: Winnick, C
name: McCann, EP
name: Hogan, A
name: Daoud, H
name: Levert, A
name: Dion, PA
name: Mitsui, J
name: Ishiura, H
name: Takahashi, Y
name: Goto, J
name: Kost, J
name: Gellera, C
name: Gkazi, AS
name: Miller, J
name: Stockton, J
name: Brooks, WS
name: Boundy, K
name: Polak, M
name: Munoz-Blanco, JL
name: Esteban-Perez, J
name: Rabano, A
name: Hardiman, O
name: Morrison, KE
name: Ticozzi, N
name: Silani, V
name: de Belleroche, J
name: Glass, JD
name: Kwok, JBJ
name: Guillemin, GJ
name: Chung, RS
name: Tsuji, S
name: Brown, RH
name: Garcia-Redondo, A
name: Rademakers, R
name: Landers, JE
name: Gitler, AD
name: Rouleau, GA
name: Cole, NJ
name: Yerbury, JJ
name: Atkin, Julie
name: Shaw, CE
name: Nicholson, GA
name: Blair, IP
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3105
subject: Genetics

description: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping, fatal neurodegenerative disorders in which the molecular and pathogenic basis remains poorly understood. Ubiquitinated protein aggregates, of which TDP-43 is a major component, are a characteristic pathological feature of most ALS and FTD patients. Here we use genome-wide linkage analysis in a large ALS/FTD kindred to identify a novel disease locus on chromosome 16p13.3. Whole-exome sequencing identified a CCNF missense mutation at this locus. Interrogation of international cohorts identified additional novel CCNF variants in familial and sporadic ALS and FTD. Enrichment of rare protein-altering CCNF variants was evident in a large sporadic ALS replication cohort. CCNF encodes cyclin F, a component of an E3 ubiquitin-protein ligase complex (SCFCyclin F). Expression of mutant CCNF in neuronal cells caused abnormal ubiquitination and accumulation of ubiquitinated proteins, including TDP-43 and a SCFCyclin F substrate. This implicates common mechanisms, linked to protein homeostasis, underlying neuronal degeneration.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Law Fon, Lew Shew Cheong, Louie Fon, Lew Lun, Lew Lun, Mary Lew, Edith Lew, Marguerite Lew, Annie Lew, Dan Lew, Archie Lew, Leong Yow, Lum Kee, Lou Bing On, Ng Git Ying, Seto Chong Yee, Yip Guey Gin.
Praktische Gewissheit und die Rationalität zweiter Ordnung
Creators: name: Renn, Joachim
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Die Schwierigkeit, Kriterien für die Rationalität der Beziehungen zwischen gesellschaftlich differenzierten Rationalitätskriterien und -bereichen anzugeben, gibt Anlass für eine Verlagerung des Fokus der zentralen soziologischen Rationalitäts-Frage. Eine Theorie gesellschaftlicher Rationalität und Rationalisierung profitiert deswegen weniger von der eventuellen Ausweisung normativer Grundlagen einer kritischen Soziologie oder von der womöglich abschließenden Evaluation der Tauglichkeit von Modellen des »rationalen Entscheiders« als von der Bearbeitung der Frage nach der Rationalität der Übergänge zwischen generalisierten Normen bzw. Regeln und Kriterien und jeweils spezifischen Kontexten ihrer Anwendung. Auf dem Wege der Bearbeitung dieser Frage kann zugleich der rationale Status des – traditional als kognitiv inferior betrachteten – impliziten bzw. praktischen Wissens freigelegt als auch die Relevanz eines solchermaßen handlungstheoretisch rehabilitierten impliziten Wissens für Fragen der Rationalität von differenzierten Makroordnungen erschlossen werden.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 1 (2013): Science & Fiction
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Soon Fong, George Soon, Rose Soon, John Soon, Jang Yin Shee, Dorothy Jang, Wong Hon Kew, Wong Mon Kwai, Lee Tone, Wong Dan Sai, Lim Hong Guey, Young Mow Bun, Soo Ngok Wing, Young Pon.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket Stubs for the following passengers: Song Get, Lung Loy, Go Ser Gim, Kwok Mong Choy, Kwok Wah Dang, Kwok Fon Kew, Lew Let Lai, Lew Nan Song, Lew Chong, Soon Tim Quai.
Polykontexturale Verhältnisse – disjunkte Rationalitäten am Beispiel von Organisationen
Creators: name: Vogd, Werner
name: Jansen, Till
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Organisationen stehen par excellence für die Kopräsenz unterschiedlicher, oftmals inkommensurabler Rationalitäten einer funktional differenzierten Gesellschaft. Im Rekurs auf die mehrwertige Logik Gotthard Günthers wird versucht, die hiermit verbundenen Verhältnisse in Organisationen konzeptionell als ein Arrangement von logischen Räumen (»Kontexturen«) zu fassen. Organisationale Praxis wird nun als eine wechselseitige Konditionierung unterschiedlicher Rationalitäten verstanden. Dabei zeigen sich verschiedene Techniken der Kopplung und Entkopplung, die einen Verbund von logischen Räumen konditionieren. Am empirischen Beispiel der Entscheidungsfindung im mitbestimmten Aufsichtsrat wird diese wechselseitige Konditionierung funktionale Differenzierungaufgezeigt.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 1 (2013): Science & Fiction
Supplementary document for SAFETRANS: a system for 3D visibility estimation and cloud cover detection - 6432929.pdf
Creators: name: de Lastic, Hector
name: Soupiona, Ourania
name: Kostopoulos, Vassilios
name: Georgoussis, Georgios
name: Papayannis, Alexandros
name: Mihelaraki, Maria
name: Siomos, Panagiotis
name: Koniditsiotis, Anastasios
name: Stavridis, Alexandros
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental material
Institutionendynamik. Zweck-, System- und Wertrationalität sozialen Handelns
Creators: name: Stachura, Mateusz
Publisher: name: Zeitschrift für Theoretische Soziologie
Year: 2013

description: Welche institutionelle Dynamik prägt die Entwicklung moderner Gesellschaften? Im ökonomischen Forschungsprogramm reagieren zweckrationale Akteure auf einen zunehmenden Umweltdruck mit dem Abbau institutioneller Normen. In der Systemtheorie reagieren soziale Systeme auf einen zunehmenden Umweltdruck mit dem Ausbau und der Verdichtung institutioneller Programme. Die Einseitigkeiten der jeweiligen Modellprognose (Institutionalisierung/Deinstitutionalisierung) legen es nahe, nach vermittelnden Alternativen Ausschau zu halten. Solch eine Alternative wird in einer Theorie sozialer »Spiele« identifiziert, die sich im Anschluss an Boltanski/Chiapello entwickeln lässt. Spiele sind Komplexe regelgeleiteten Handelns, das zugleich kompetitiv und normativ reguliert ist. Je nach der Spielkonstellation (Geschlossenheit oder Distinktionsschwäche) führt der zunehmende Konkurrenzdruck dabei entweder zu einer Verschärfung oder einer Entschärfung der institutionellen Spielregeln des Handelns.
description: Zeitschrift für Theoretische Soziologie, Bd. 2 Nr. 1 (2013): Science & Fiction