cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A heme periplasmic-binding protein hHBP mediates heme transport in Haemophilus ducreyi
Creators: name: Robinson, Renee
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Biology, Microbiology.

description: Haemophilus ducreyi, a Gram-negative and heme-dependent bacterium, is the causative agent of chancroid, a genital ulcer sexually transmitted infection. Although the precise molecular mechanism of heme acquisition in H. ducreyi is unclear, heme uptake likely proceeds via a receptor mediated process. The initial event involves binding to either of two outer membrane receptors, TdhA and HgbA. Once heme is deposited into the periplasmic space, a heme permease is postulated to transport heme across the periplasmic space to the inner membrane. In prior experiments, using protein expression profiling of the H. ducreyi periplasmic proteome, we identified a periplasmic-binding protein hHBP that we propose is a component of a heme trafficking operon. Biochemical and genetic approaches were used to functionally characterize hHBP. First, purified hHBP was incubated with increasing concentrations of heme and the mixtures were resolved by non-denaturing polyacylamide gel electrophoresis. Separated proteins were transferred onto PVDF membranes and heme-protein complexes were detected by enhanced chemiluminescence (ECL). Second, the hhbp gene was cloned in the E. coli recombinant mutant E. coli FB827 dppA::Km mppA::Cm (pAM238-HasR) which expresses the Serratia marcescens HasR heme receptor allowing heme translocaton into the periplasm, but denies heme entry into the cytoplasm because of the presence of the double mutation (dppA::Km mppA::Cm) resulting in a mutant lacking the two periplasmic proteins DppA and MppA. We found that heme binding to hHBP was saturable as determined by ECL. Genetic complementation in trans with hhbp repaired the growth defect of the mutant E. coli for heme utilization as an iron source. The growth restoration was comparable to that seen with the E. coli mutant complemented with the intact Dpp permease. Additionally, growth of the mutant was not rescued with the empty plasmid vector. We concluded that H. ducreyi hHBP functionally binds heme. Complementation of the E. coli mutant for heme competency supports the proposal that hHBP participates in the transit of heme in H. ducreyi.
Neosebastidae Matsubara 1943
Creators: name: Smith, W. Leo
name: Everman, Elizabeth
name: Richardson, Clara
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Scorpaeniformes
Neosebastidae

description: Neosebastidae Matsubara, 1943   Type genus: Neosebastes Guichenot, 1867
 Sister taxon: Plectrogeniidae
 Concept and content: 18 species classified in two genera: Maxillicosta and Neosebastes
 Phenotypic diagnosis: No unambiguously optimized morphological synapomorphies diagnose Neosebastidae, although the family is supported by a morphological transformation through accelerated character optimization.
 Support statistics: The bootstrap support for this clade was 1.00.
 Systematic comment: Familial and generic composition and species recognition follow Eschmeyer et al. (2017).
description: Published as part of Smith, W. Leo, Everman, Elizabeth & Richardson, Clara, 2018, Phylogeny and Taxonomy of Flatheads, Scorpionfishes, Sea Robins, and Stonefishes (Percomorpha: Scorpaeniformes) and the Evolution of the Lachrymal Saber, pp. 94-119 in Copeia 106 (1) on page 118, DOI: 10.1643/CG-17-669, http://zenodo.org/record/13230683
Millennial-scale climate variability in North America during the past 14,000 years
Creators: name: Viau, Andre Ernest J
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Physical Geography.
subject: Geophysics.

description: Variations in the Earth's climate occur on many time and space scales. A recent focus of paleoclimate research is the so-called 1500-year North Atlantic quasi-periodic cycle, and has revolved around three main themes. First, what are the underlying causes and physical mechanisms governing these millennial-scale variations? Next, are they global or restricted to certain sensitive regions of the planet? Last, what is the magnitude of the temperature changes of these variations, and do they vary in time and space? This dissertation explores millennial-scale climate variability in North America during the past 14,000 years using a dense network of fossil pollen data, which is used as proxy for climate variations. Three independent approaches are used to quantify these changes. A mixture modelling analysis of radiocarbon dates on pollen transitions, a principal component analysis of pollen diagrams from all of North America, and a mean July temperature reconstruction based on the method of modern analogue (MAT) all reveal millennial-scale climate variability throughout North America during the past 14,000 years. The identified transitions generally correlate well with other proxy-climate records from the North Atlantic region. However, certain mismatches occurred particularly at 9, 6 and 4 ka BP. If we assume the dominant millennial-scale period is 1150-years, the records become more consistent. North American temperature variability was not unidirectional nor uniformly distributed in space, suggesting large-scale ocean-atmospheric reorganizations at the transitions. Correlation between the proxy-climate and cosmogenic nuclide records supports a variable solar output hypothesis as the fundamental cause for century to millennial-scale climate variability. The mean July temperature of North America varied on the order of 0.2 to 0.4°C during the Holocene and 0.4° and 0.6°C during the deglaciation. Temperature was more variable during the late glacial, possibly due to the impact on the climate of massive meltwater pulses into the North Atlantic, further amplified through ocean dynamic processes. Recent global warming estimated as an increase in temperature of 0.4--0.6°C, is therefore greater than the estimated natural variation of the past 10,000 years, providing further evidence that recent increases in atmospheric CO2 have played a major role in modern warming.
Protein factors involved in the assembly of very low density lipoproteins
Creators: name: Links, Philip Harold
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Chemistry, Biochemistry.

description: Genetic data have suggested a correlation between apolipoprotein C-III (apoC-III) and familial combined hyperlipidemia (FCHL). This observation has been confirmed by clinical data that show an elevation of circulating apoC-III in FCHL patients. Yet the underlying mechanism for the hyperlipidemic effect of apoC-III remains unclear. We postulate that an elevation of apoC-III expression might be associated with enhanced hepatic very low density lipoprotein (VLDL) secretion. To test this hypothesis, human apoC-III cDNA was transfected into McA-RH7777 rat hepatoma cells, that lacked endogenous apoC-III protein; triacylglycerol (TG) apolipoprotein B and VLDL secretion was determined. In transient (p<.0005) and stable transfectants (p<.0008), expression of recombinant apoC-III led to a two-fold increase in 3H-TG secretion only in the presence of 0.4 mM exogenous oleate (OA). This increased 3H-TG secretion was specifically associated with the VLDL1 sub fraction ( Sf) > 100. ApoB-100 in the VLDL1 sub fraction also increased with apoC-III expression. I postulated that structural determinants shared by the other apoC proteins, apoC-I and apoC-II may also lead to an increase in VLDLI. Stable cell lines expressing apoC-I and apoC-II also stimulated 3H-TG secretion as well as apoB100 in the VLDL 1 fraction. Thus, hepatic apoC levels increase VLDL1 secretion particularly in the presence of OA. Finally I attempted to identify a novel TG synthetic enzyme, phosphatidate phosphohydrolase (PAP-1). This enzyme activity hydrolyzes the phosphate group of phosphatidic acid to produce diacylglycerol (DG) for TG production. Since limiting TG levels lead to apolipoprotein B-100 degradation and aborted lipoprotein synthesis I postulate that PAP-1 may be involved in lipoprotein assembly and secretion. This research addresses two accessory protein factors apoC-III and PAP-1, involved in lipid mobilization for TG rich lipoprotein assembly and secretion.
Platycephalidae Swainson 1839
Creators: name: Smith, W. Leo
name: Everman, Elizabeth
name: Richardson, Clara
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Scorpaeniformes
Platycephalidae

description: Platycephalidae Swainson, 1839   Type genus: Platycephalus Bloch, 1795
 Sister taxon: Hoplichthyidae þ Triglidae
 Concept and content: 84 species classified in two subfamilies and 17 genera: Oniigociinae: Ambiserrula, Cociella, Cymbacephalus, Grammoplites, Inegocia, Kumococius, Onigocia, Papilloculiceps, Ratabulus, Rogadius, Solitas, Suggrundus, Sunagocia, and Thysanophrys; Platycephalinae: Elates and Platycephalus; incertae sedis: Leviprora
 Phenotypic diagnosis: No unambiguously optimized morphological synapomorphies diagnose Platycephalidae, although the family is supported by a morphological transformation through accelerated character optimization.
 Support statistics: The bootstrap support for this clade was 0.97.
 Systematic comment: Familial and subfamilial classification follows Imamura (1996). Generic composition and species recognition follow Eschmeyer et al. (2017) except for the synonymy of Sorsogona in Ratabulus following Imamura (1996).
description: Published as part of Smith, W. Leo, Everman, Elizabeth & Richardson, Clara, 2018, Phylogeny and Taxonomy of Flatheads, Scorpionfishes, Sea Robins, and Stonefishes (Percomorpha: Scorpaeniformes) and the Evolution of the Lachrymal Saber, pp. 94-119 in Copeia 106 (1) on page 118, DOI: 10.1643/CG-17-669, http://zenodo.org/record/13230683
title: Building Scientific Tools : From Heat Transport to Particulate Systems
Creators: name: Kopera, Bernd
Publisher: name: University of Bayreuth
Year: 2020
Subjects: subject: heat transport
subject: particulate systems
subject: 540

description: During my PhD, I developed automated measurement and data analysis tools and applied them to specific research questions. These tools allowed my colleagues and me to gain a better understanding of nanostructured particulate systems. Furthermore, we could deduce structure-property relationships that govern heat flow in particulate matter. Most of the tools I created come in the form of software. My programming languages of choice are Python 3 and C++. They allow both rapid and object oriented software development. My research focused on two main topics: heat transport and particulate systems. Both topics are intertwined in the diverse projects I completed during my PhD. Each project had its own, unique challenges that I addressed with programming.
Plectrogeniidae Fowler 1938
Creators: name: Smith, W. Leo
name: Everman, Elizabeth
name: Richardson, Clara
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Scorpaeniformes
Plectrogeniidae

description: Plectrogeniidae Fowler, 1938   Type genus: Plectrogenium Gilbert, 1905
 Sister taxon: Neosebastidae
 Concept and content: Four species classified in two genera: Bembradium and Plectrogenium
 Phenotypic diagnosis: Skinny lateral-line sensory canal between pterotic and preopercle absent (character 23, state 1); posterior pelvic fossa present, fossae meeting (character 52, state 1); dorsal-fin stay cartilaginous (character 66, state 2); anal-fin stay cartilaginous (character 67, state 2); hyohyoides inferioris present (character 84, state 1).
 Support statistics: The bootstrap support for this clade was 0.34.
 Systematic comment: Familial classification follows Imamura (1996). Generic composition and species recognition follow Eschmeyer et al. (2017).
description: Published as part of Smith, W. Leo, Everman, Elizabeth & Richardson, Clara, 2018, Phylogeny and Taxonomy of Flatheads, Scorpionfishes, Sea Robins, and Stonefishes (Percomorpha: Scorpaeniformes) and the Evolution of the Lachrymal Saber, pp. 94-119 in Copeia 106 (1) on page 118, DOI: 10.1643/CG-17-669, http://zenodo.org/record/13230683
Integrative TiSS profiling with iTiSS
Creators: name: Jürges, Christopher S.
name: Dölken, Lars
name: Erhard, Florian
Publisher: name: Zenodo
Year: 2020

description: Here we present all our data and scripts necessary to reproduce all our figures and tables for our publication of iTiSS. Each folder includes a start.bash file, which can be executed to run all scripts in its and its subdirectory folders. Those start.bash files include detail comments on each script executed. To prevent any legal problems, the other tools tested are not included in this upload and need to be downloaded separately (see start.bash file in the programs-folder for instructions).
Communication and inquiry: John Dewey on the role of language in intelligence
Creators: name: Zaslow, Josh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Philosophy.

description: In this thesis I examine John Dewey's discussion of the natural bases of inquiry---his attempt to show how intelligent behaviour is continuous with, and a special case of, organic behaviour more generally conceived. I argue that as "the tool of tools", he takes language to be a crucial element in intelligence as it enables an organism to exert control over the formation of its habits through inquiry (EN: 134). For behaviour to be intelligent, he thinks, not only requires an organism to exert control over its habit formation but also requires that an organism exercise control over its behaviour using the best means available. The scientific method of forming beliefs, he claims, provides the best available basis for intelligent action. It is for this reason that Dewey takes scientific inquiries, in particular, to be exemplary of inquiry and why he identifies the scientific method as method of intelligence.
Learning to cope with trips: retention and generalisability of fall-resisting skills across the adult lifespan
Creators: name: Koenig, Matthias
Publisher: name: London South Bank University
Year: 2020

description: Daily-life locomotion constantly challenges our neuromotor system, requiring adjustments in motor strategies to cope with external perturbations (e.g. a trip), control stability and avoid falls. Though knowledge about the effectiveness of perturbation-based interventions for improving fall-resisting skills in older adults has grown considerably, the effects of age and different protocol parameters on the adaptability (i.e adaptation, retention, generalisability) of the balance control system are not well established. This dissertation examined the adaptability and specificity of fall-resisting skills across the adult lifespan, with the perspective that the insight gained could improve both the effectiveness and efficicency of the assessment and training of fall-resisting skills. Four studies were conducted, comprising of both cross-sectional and longitudinal (14 weeks) designs. The first part of the dissertation focused on the specificity of the assessment of reactive dynamic stability control and the second part on adaptability to trip-perturbation exposure and how this varies with practice dose or age (i.e. young, middle-aged, old). Firstly, a gradual, age-related decline in reactive stepping performance was confirmed for different stepping modes. More importantly, it appears that volitional stepping characteristics have limited potential for discriminating between individuals or groups with quite different balance recovery capabilities. Therefore, volitional stepping tasks may not be sensitive enough for clinical application. Secondly, although the adaptability of reactive gait stability control during a single bout of trip-perturbations remains highly effective across the adult lifespan (which could counteract the initially poorer ability to cope with sudden balance loss in older age), retention of these improvements over several months seems to be diminished with ageing and dependent on a specific number of perturbations. Finally, the robust adaptations in stability control could not benefit recovery performance in an untrained reactive balance task, suggesting task specificity of learning. Profound differences in the spatiotemporal organisation of muscle activation patterns, i.e. muscle synergies, indicate a diverging modular control to different perturbations, possibly preventing inter-task generalisation of adaptations in stability control.
Investigation of the oncolytic activity of vesicular stomatitis virus in murine cancer models
Creators: name: Paterson, Jennifer Marie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Chemistry, Biochemistry.
subject: Health Sciences, Immunology.
subject: Health Sciences, Oncology.

description: Interferon (IFN) inducing strains of Vesicular stomatitis virus (VSV) replicate selectively in transformed cells and exert impressive oncolytic abilities in murine tumour models. Interestingly, in some tumour models, complete tumour cures can only be obtained by administering multiple intravenous doses of virus, indicating that there must be barriers that limit the ability of a single dose of virus to eliminate a tumour. The goal of the current research was to examine the intravenous delivery of IFN inducing VSV to subcutaneous tumours, as well as subsequent spread and tumour killing activity. It was found that intravenous delivery is inefficient and seems to result in preferential delivery of virus to the tumour rim. However, apoptosis is induced throughout the uninfected core of the tumour, indicating that VSV may induce indirect killing of tumour cells. While the specific cause of this apparent bystander effect was not determined, it was observed that VSV treatment also resulted in collapse of functional tumour vasculature.
Design and evaluation of a dynamic knee-ankle-foot orthosis
Creators: name: Yakimovich, Terris
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Engineering, Biomedical.
subject: Engineering, Mechanical.

description: Conventional knee-ankle-foot orthoses (KAFOs) or leg braces lock the knee in full extension and therefore do not permit a natural gait pattern. A new electro-mechanical dynamic knee-ankle-foot orthosis (DKAFO) that incorporates a new dynamic knee joint (DKJ) was designed to provide a more natural gait for people with knee extensor muscle weakness. The DKAFO inhibits knee flexion while allowing knee extension during weight bearing. During swing or other non-weight bearing activities, the DKAFO allows free knee motion. A prototype knee joint was mechanically tested to determine the moment at failure, loading behaviour, and device safety. Quantitative kinematic gait analysis of three able-bodied subjects and three KAFO users showed that walking with the DKAFO had a minimal effect on normal gait. The DKAFO offered increased knee motion in swing and a reduction in gait abnormalities for some subjects with disabilities. Future efforts will be made to modify the design to increase the factor of safety, and reduce DKJ dimensions.
Expression of discoidin domain receptors in 3T3-L1 preadipocytes and adipocytes
Creators: name: Zurakowski, Honorata
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Biology, Cell.

description: Discoidin domain receptors (DDRs) are receptor tyrosine kinases, of which there are members, DDR1 and DDR2, which are activated by collagen and are involved in cellular proliferation. Therefore, given their role in extracellular matrix interactions and proliferation, both of which affect adipogenesis, we hypothesized that the DDRs influence preadipocyte biology, adipogenesis and adipocyte biology. DDR1 protein expression was decreased in 3T3-L1 a dipocytes versus preadipocytes, whereas, DDR1 mRNA expression was decreased at day 4 of 3T3-L1 adipogenesis compared to day 0. DDR2 mRNA expression was reduced at day 2 compared to day 0 of adipogenesis. DDR2-overexpressing preadipocytes display reduced subconfluent 3T3-L1 proliferation and reduced mitotic clonal expansion. DDR2-overexpressing adipocytes were larger and had a greater triacylglycerol mass compared to empty-vector control adipocytes. DDR2-overexpressing adipocytes exhibited a decrease in insulin-stimulated phophorylation of IRS-1 and an increase in Akt and ERK1/2 phosphorylation. Overexpression of DDR2 in preadipocytes also led to decreased phophorylation of IRS-1 upon stimulation with insulin, without an effect on Akt and ERK1/2 phosphorylation. These results suggest that DDR2 is pertinent to 3T3-L1 adipogenesis.
Targeting of SARS-CoV-2 nsp4 Crucial Binding Sites using Some Antiviral Drugs and Small Molecules: A molecular Docking Study
Creators: name: dewedar, doaa
name: Abdelmalek
name: Bayomi
Publisher: name: Zenodo
Year: 2024

description: In the field of structural bioinformatics, our research focused on targeting binding sites in the NSP4 protein of SARS-CoV-2. Utilizing molecular docking, secondary structure prediction, and homology modeling, we explored potential interactions with antiviral drugs and small molecules. Our study identified Verdinexor as a promising drug candidate with high binding affinity to NSP4, suggesting its potential as a broad-spectrum antiviral. These findings underscore the significance of inhibiting NSP4 to prevent viral replication and spread.
From fermionic spin-Calogero-Sutherland models to the Haldane-Shastry chain by freezing
Creators: name: Lamers, Jules
name: Serban, Didina
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mathematical Physics (math-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: The Haldane-Shastry spin chain has a myriad of remarkable properties, including Yangian symmetry and, for spin $1/2$, explicit highest-weight eigenvectors featuring (the case $α= 1/2$ of) Jack polynomials. This stems from the spin-Calogero-Sutherland model, which reduces to Haldane-Shastry in a special `freezing' limit.
 In this work we clarify various points that, to the best of our knowledge, were missing in the literature. We have two main results. First, we show that freezing the $\mathit{fermionic}$ spin-1/2 Calogero-Sutherland model naturally accounts for the precise form of the Haldane-Shastry wave functions, including the Vandermonde factor squared. Second, we use the fermionic framework to prove the claim of Bernard-Gaudin-Haldane-Pasquier that the Yangian highest-weight eigenvectors of the $SU(r)$-version of the Haldane-Shastry chain arise by freezing $SU(r-1)$ spin-Calogero-Sutherland eigenvectors at $α= 1/2$.
description: v1: 38 pages, 1 figure, 1 table. v2: various minor improvements; 43 pages, 2 figures, 1 table
Deux modèles d'intégration politique: Le multiculturalisme canadien et le républicanisme français
Creators: name: Picard, Hélène
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Political Science, General.

description: Cette recherche aborde la question de la transformation du modèle français d'intégration, vers une forme apparentée au multiculturalisme. Le but de cette recherche est de proposer la conception d'un modèle hybride d'intégration à partir d'une comparaison de deux modèles: le multiculturalisme canadien et le républicanisme français. Ce modèle hybride proposé fut baptisé de "multipublicanisme". Bien que de comparer le multiculturalisme avec le républicanisme soit paradoxale, il semble exister des liens intéressants dans l'arène intellectuelle afin de concevoir un nouveau modèle d'intégration pour le Canada et la France. Depuis plusieurs années, on assiste à des débats théorique et médiatique sur la situation de la laïcité (en France), des accommodements raisonnables (au Québec/Canada) sans oublier les problèmes qui émergent dans les villes canadiennes et les banlieues françaises. La présente thèse s'inscrit dans une démarche théorique et se penche sur la transformation progressive actuelle du modèle d'intégration français républicain vers une forme apparente au modèle d'intégration multiculturel canadien et ce, autour des plans religieux et urbains. Partant de grandes traditions théoriques (formelle et pragmatique), nous avons été en mesure de concevoir une définition embryonnaire du multipublicanisme qui pourrait servir à l'avancement de la recherche sur les questions d'intégration en France et au Canada.
Triglidae Rafinesque 1815
Creators: name: Smith, W. Leo
name: Everman, Elizabeth
name: Richardson, Clara
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Scorpaeniformes
Triglidae

description: Triglidae Rafinesque, 1815   Type genus: Trigla Linnaeus, 1758
 Sister taxon: Hoplichthyidae
 Concept and content: 173 species classified in four subfamilies and 15 genera: Peristediinae: Gargariscus, Heminodus, Paraheminodus, Peristedion, Satyrichthys, and Scalicus; Prionotinae: Bellator and Prionotus; Pterygotriglinae: Bovitrigla and Pterygotrigla; Triglinae: Chelidonichthys, Eutrigla, Lepidotrigla, Trigla, and Trigloporus
 Phenotypic diagnosis: First and third circumorbitals attached (character 2, state 1); third circumorbital and lateral ethmoid attached (character 4, state 1); nasal and neurocranium sutured (character 14, state 1); notch between ascending process and cranial condyle absent (character 27, state 1); transversus ventralis anterior and posterior separated (character 92, state 1); transversus ventralis posterior with a tendon anteriorly (character 93, state 1); division of bundles of adductor superficialis serving free pectoral-fin rays present (character 95, state 1).
 Support statistics: The bootstrap support for this clade was 1.00.
 Systematic comment: Familial classification and treatment of Peristediinae as a triglid subfamily follows our phylogeny and the phylogeny from Portnoy et al. (2017). The remaining triglid subfamilies follow the tribes from Richards and Jones (2002). Generic composition and species recognition follow Kawai (2008) and Eschmeyer et al. (2017).
description: Published as part of Smith, W. Leo, Everman, Elizabeth & Richardson, Clara, 2018, Phylogeny and Taxonomy of Flatheads, Scorpionfishes, Sea Robins, and Stonefishes (Percomorpha: Scorpaeniformes) and the Evolution of the Lachrymal Saber, pp. 94-119 in Copeia 106 (1) on page 119, DOI: 10.1643/CG-17-669, http://zenodo.org/record/13230683
"The concerned and thoughtful musical citizen": Music analysis as sufficient explanation
Creators: name: Fitzpatrick, Michael D
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Music.

description: Some scholars have proposed the application of scientific method to the practice of music theory and analysis. This thesis examines two such frameworks: one developed by Milton Babbitt, and another by Matthew Brown and Douglas Dempster. The first part presents Babbitt's prescriptions of "scientific language and method," along with his distinction between analytical explanation and description, and an outline of Hempel and Oppenheim's Deductive-Nomological model of explanation. The second part focuses on Brown and Dempster's application of scientific method to music theory and analysis and contrasts their view with Babbitt's. Within the thesis, I make the following restrictions to my theoretical framework: music theory and analysis are explanatory activities---as opposed to descriptive---and music theories are composed of generalized empirical statements concerning individual works on an analytical level. In its consideration of large methodological questions, this thesis promotes the continued integrity of the discipline of music theory and analysis.
title: Die Bedeutung der Liebe: Eindrücke aus Südasien [formal angepasste Version der ursprünglichen Textfassung vom November 2014]
Creators: name: Kachru, Sonam
Publisher: name: MPIB - Max Planck Institute for Human Development
Year: 2020

description: Geschichte der Gefühle - Einblicke in die Forschung
A new approach to ice-induced vibrations through the conservation of momentum
Creators: name: Jeong, Sumin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Engineering, Mechanical.

description: This thesis proposes a new ice-induced vibration model which is not based on the existing ice-induced vibration (IIV) modeling approaches. The new model is derived from a different perspective so that it is able to respond to the influence of fluid flow and shortcomings in existing ice-induced vibration models. The effect of a flowing fluid on ice-induced vibrations has not been investigated in past research inspite of its significant contributions to the dynamics of both structure and ice. By combining the equation of a one degree-of-freedom oscillator with Morison's equation, the flow effect is added to the structural response and its influence is examined. The deficiencies of the existing IIV models are investigated by reproducing two existing models, and demonstrating the need for a new model. The new model, the impact IIV model, which is developed from the conservation of momentum is completed by the inclusion of the flow effect on the structure.
The evolution of paralogous enzymes MAT and MATX within the Euglenida and beyond
Creators: name: Szabová, Jana
name: Yubuki, Naoji
name: Leander, Brian S.
name: Triemer, Richard E.
name: Hampl, Vladimír
Publisher: name: BioMed Central
Year: 2015

description: Background. Methionine adenosyltransferase (MAT) is a ubiquitous essential enzyme that, in eukaryotes, occurs in two relatively divergent paralogues: MAT and MATX. MATX has a punctate distribution across the tree of eukaryotes and, except for a few cases, is mutually exclusive with MAT. This phylogenetic pattern could have arisen by either differential loss of old paralogues or the spread of one of these paralogues by horizontal gene transfer. Our aim was to map the distribution of MAT/MATX genes within the Euglenida in order to more comprehensively characterize the evolutionary history of MATX. Results: We generated 26 new sequences from 23 different lineages of euglenids and one prasinophyte alga Pyramimonas parkeae. MATX was present only in photoautotrophic euglenids. The mixotroph Rapaza viridis and the prasinophyte alga Pyramimonas parkeae, which harbors chloroplasts that are most closely related to the chloroplasts in photoautotrophic euglenids, both possessed only the MAT paralogue. We found both the MAT and MATX paralogues in two photoautotrophic species (Phacus orbicularis and Monomorphina pyrum). The significant conflict between eukaryotic phylogenies inferred from MATX and SSU rDNA data represents strong evidence that MATX paralogues have undergone horizontal gene transfer across the tree of eukaryotes. Conclusions: Our results suggest that MATX entered the euglenid lineage in a single horizontal gene transfer event that took place after the secondary endosymbiotic origin of the euglenid chloroplast. The origin of the MATX paralogue is unclear, and it cannot be excluded that it arose by a gene duplication event before the most recent common ancestor of eukaryotes.
Identifying meteorite droppers among the population of bright 'sporadic' bolides imaged by the Spanish Meteor Network during the spring of 2022
Creators: name: Peña-Asensio, Eloy
name: Trigo-Rodríguez, Josep M.
name: Rimola, Albert
name: Corretgé-Gilart, Marc
name: Koschny, Detlef
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The extraordinary weather conditions available between February and March 2022 over Spain have allowed us to analyze the brightest fireballs recorded by the monitoring stations of the Spanish Meteor Network (SPMN). We study the atmospheric flight of 15 large meteoroids to determine if they are meteorite dropper events to prepare campaigns to search for freshly fallen extraterrestrial material. We investigate their origins in the Solar System and their dynamic association with parent bodies and meteoroid streams. Employing our Python pipeline 3D-FireTOC, we reconstruct the atmospheric trajectory utilizing ground-based multi-station observations and compute the heliocentric orbit. In addition, we apply an ablation model to estimate the initial and terminal mass of each event. Using a dissimilarity criterion and propagating backward in time, we check the connection of these meteoroids with known complexes and near-Earth objects. We also calculate if the orbits are compatible with recent meteoroid ejections. We find that ~27% of these fireballs are dynamically associated with minor meteoroid streams and exhibit physical properties of cometary bodies, as well as one associated with a near-Earth asteroid. We identify two meteorite-producing events; however, the on-site search was unsuccessful. By considering that these fireballs are mostly produced by cm-sized rocks that might be the fragmentation product of much larger meteoroids, our findings emphasize the idea that the population of near-Earth objects is a source of near-term impact hazards, existing large Earth-colliding meteoroids in the known complexes.
description: Accepted in MNRAS
Canadian English teachers in South Korea: A look at how interpersonal and intercultural communication impacts the experience of working abroad
Creators: name: Pipin, Katarzyna
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: subject: Mass Communications.

description: Teaching English abroad, particularly in South Korea, is a popular choice for many Canadian university graduates. This research begins to examine the unique experiences of young, educated Canadians who lived and worked in this East Asian country for an extended period of time. This study is based on a qualitative approach, using semi-structured interviews with 10 Canadians in the Ottawa area who taught English in South Korea for a period of one year or longer between 2001 and 2006. The findings show that while most of those interviewed had little knowledge of South Korea before leaving, their communication with other expatriates and the local Korean population resulted in predominantly positive perceptions of both their time abroad and of the Korean culture. This thesis contributes to the field of expatriate literature, where limited attention has been devoted to teaching abroad, and adds to the field of communication by bringing into it existing literature on expatriate management. Key words: expatriate management, social support, intercultural contact, repatriation.
The political and electoral geography of Quebec: A critical analysis of the 1998 Quebec provincial election
Creators: name: Klaas, Zachary
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Geography.
subject: Political Science, General.

description: The results of the 1998 provincial election in Quebec reveal the existence of six distinct "electoral regions" in the province. The concentration of the vote for the three major political parties, the Parti Quebecois (PQ), the Parti liberal du Quebec (PLQ) and the Action democratique du Quebec (ADQ) defines these regions, in conjunction with information provided by a geographical and statistical database of indicators representing spaces, actors and rationales of action. The portrait of Quebec afforded us by an analysis of such a research database suggests strongly that there are "many Quebecs" rather than a unitary Quebec. A Quebec seeking to remain a political unity must culturally recognise the existence of six distinct regions within it, a number of which differ on basic matters with the majority culture of the province.
Trade and labor standards: A theoretical and empirical analysis of the linkages
Creators: name: Samy, Yiagadeesen
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Economics, General.

description: This thesis contains three essays and a short introductory chapter. The main theme of the thesis is the interaction of international trade and labor standards, which has been at the forefront of recent trade negotiations, both at the regional and multilateral level. Even though the essays in this thesis share a common theme, they can be read independently without impeding the reader's understanding of the issues discussed in each. The first essay theoretically considers the impact of labor standards on comparative advantage through their effects on the terms of trade. I use a standard Heckscher-Ohlin trade model and analyze the effects of incorporating a standard that takes resources away from the tradeable sectors. I find that movement in the terms of trade due to the imposition of a standard depends on whether the standard withdraws resources from the import or the export sector, and also on the capital-labor ratios of the tradeable goods. These results imply that there exist grounds for countries to set higher than optimal levels of standards in order to obtain terms of trade gains. The second essay makes use of cross sectional data for a sample of more than seventy (developed and developing) countries to analyze the issue of trade and labor standards. It seeks to answer two questions, first, whether the imposition of labor standards affects the export performance of countries, and second, whether labor standards affect foreign direct investment (FDI) flows. The third essay, unlike the general approach in the literature which is based on cross-sectional analysis, uses a time series approach based on the structural change literature to analyze and compare the effects of different measures of labor standards on the behavior of exports for Canada and the United States. It also provides an analysis of the issue of convergence of labor standards between the two countries within the context of the North-American Free Trade Agreement. Overall, the empirical results from the second and third essays suggest that caution should be exercised before drawing broad conclusions regarding the magnitude and direction of the effects of labor standards on both export performance and FDI flows, which can have very different policy implications.
Hierarchical multinomial processing tree models for meta-analysis of diagnostic accuracy studies
Creators: name: Guolo, Annamaria
Publisher: name: arXiv
Year: 2023
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences
subject: 62F03, 62F12, 62P10

description: Meta-analysis represents a widely accepted approach for evaluating the accuracy of diagnostic tools in clinical and psychological investigations. This paper investigates the applicability of multinomial tree models recently suggested in the literature under a fixed-effects formulation for assessing the accuracy of binary classification tools. The model proposed in this paper extends previous results to a hierarchical structure accounting for the variability between the studies included in the meta-analysis. Interestingly, the resulting hierarchical multinomial tree model resembles the well-known bivariate random-effects model under an exact within-study distribution for the number of true positives and true negatives subjects, with the additional advantage of providing an estimate of the prevalences of disease from each study. The proposal is in line with a latent-trait approach, where inference is performed according to a frequentist point of view. The applicability of the proposed model and its performance with respect to the approximate bivariate random-effects model based on normality assumptions commonly used in the literature is evaluated in a series of simulation studies. Methods are applied to a real meta-analysis about the accuracy of the confusion assessment method as delirium screening tool.
Glucose, glucose transporters and neurogenesis
Creators: name: Teutenberg, Kevin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Neuroscience.
subject: Psychology, Physiological.

description: Since the pioneering work of Altman in the late 60's, much has been learned about the generation of neurons in the adult brains of several species, including mice, rats, and humans. An underlying assumption is that these newborn neurons acquire their energy, in the form of glucose, in a similar manner to mature neurons: via glucose transporters. Using BRDU and double immunohistochemistry, we investigated the relationship between hippocampal neurogenesis and glucose transporters, as well as monocarboxylate transporters. Unexpectedly, the results suggest that newborn neurons do not acquire their energy via the major glucose transporters (1, 3, 4, and 8), nor via either monocarboxylate transporter tested (1 and 2). Future studies will have to resolve whether lesser known glucose transporters carry this function or if other mechanisms are used to provide metabolic energy to newborn neurons.
An investigation of the relationship between emotional intelligence and specific learning difficulties (SLDs)
Creators: name: McLean, Lana D.
Publisher: name: Swinburne
Year: 2024

description: The present thesis provides empirical evidence of a significant correlation between EI and SLDs which includes dyslexia, dyscalculia, dyspraxia and ADD. This supports the growing recognition that emotions significantly impact on the way a person performs, interacts and learns. The findings in the two studies contribute to the growing interest of professionals in the field of education and mental health to help find preventions and treatments for SLDs.
Process engineering of Pichia pastoris cultivation for the production of a phytase with GAP promoter
Creators: name: Tang, Shuiquan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Engineering, Chemical.

description: Pichia pastoris (P. pastoris) is a popular host for recombinant protein production. In this work, phytase production with P. pastoris under GAP promoter was studied. In the first part of this study, feasibility of using crude glycerol from biodiesel production as the sole carbon source for P. pastoris cultivation was investigated. Although growth inhibition was found in batch cultivations stated with high concentration of biodiesel glycerol, efficient high cell density production was realized by fed-batch cultivation started with a low concentration of biodiesel glycerol. The second part of this work focused on the study of growth kinetics with continuous cultivations under different dilution rates. The influences of dilution rate upon cell growth and phytase production were revealed and characterized with empirical equations. Based on these results, a simple kinetic model was established and model parameters were estimated mainly based on these results as well. Good agreement with experimental results was found when this model was applied to the prediction of cell growth and phytase production in regular fed-batch cultivation processes.
Sweeping gas membrane evaporative cooling for the enhanced performance of vapour compression refrigeration
Creators: name: Smith, Benjamin D
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Engineering, Chemical.

description: A sweeping gas membrane evaporative (SGME) cooling system was developed to remove heat from the condenser of a vapour compression chiller. The chiller was designed for hot environments and could only achieve a coefficient of performance (COP) of 1.0 using an air-cooled condenser. In this work, the condenser was modified to have circulating water absorb heat, which was then cooled in membrane modules by evaporation across a hydrophobic membrane into an air stream. Steady-state operation of the chiller was achieved with the SGME system. Increasing either air flow or water circulation rate increased the COP of the chiller, which reached a value of 1.83 with an optimal heat load of 435 W. The SGME system was then compared to cooling towers, a conventional method of evaporative heat removal. It was found that the SGME system provided more heat removal per unit volume and per unit of air flow than any investigated cooling tower. 89% of the heat removal was attributed to evaporation, and only 1.5% of the water entering the module was lost to evaporation, making the system more compact and efficient than towers. The sweeping gas membrane evaporation system was superior to both air-cooled condensers and to cooling towers.
Statut canonique de l'école Catholique au Congo-Zaïre à la lumière du Canon 803
Creators: name: Kabongo Lukunda, Bertrand
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Religion, General.
subject: Law.
subject: Education, Administration.

description: Toute institution a ses règles de bonne gouvernance qui fixent son champ de compétence et définissent sa nature juridique. Il en est de meme de l'Église catholique et de ses institutions. Les institutions scolaires catholiques sont non seulement soumises aux exigences canoniques qui leur assurent leur catholicité, mais aussi aux lois civiles qui déterminent leur nature. Cette thèse présente les raisons, historiques et actuelles du dysfonctionnement du système scolaire congolais en général et de l'enseignement catholique en particulier. Elle propose aussi les voies qui ouvrent vers une école réellement catholique. Au Congo, l'école catholique est soit privée, soit publique confessionnelle. C'est sous ce dernier aspect que son étude devient intéressante. L'État et l'Église se sont engagés comme collaborateurs sur base de la Convention de gestion signée en 1977. Celle-ci définit le champ de compétence de chacun. Malheureusement, cette convention qui devrait garantir le bon fonctionnement des écoles est aussi source des conflits qui opposent les principaux signataires. Il ne peut en être autrement dans un régime dictatorial ou la volonté d'une seule personne ou d'un groupe de personnes a aussi force de loi. La loi-cadre de l'enseignement national promulguée en 1986, tout en fournissant les éléments valables pour la bonne gestion des écoles, connaît aussi le sort des autres textes juridique Congolais. Les enfants catholique comme tous les autres enfants, ont droit a une éducation saine et intégrale. L'Église comme "mère et éducatrice" se fait le devoir de fonder et de gérer ses propres écoles. Elle donne les éléments formels et substantiels qui déterminent l'identité d'une école qui se veut catholique. Ces éléments fixent les quatre champs de compétence de l'école catholique: qualité de l'enseignement général, qualité de l'enseignement religieux, qualité de l'éducation catholique, implication de l'école catholique dans la mission de l'Église. Comment concilier la législation civile et la législation canonique? L'étude du canon 803 du Code de droit canonique fournit des éléments valables pour un nouveau débat sur la nature juridique des écoles au Congo. C'est le travail que nous avons réalisé dans cette thèse pour l'interêt de tous, parents, élèves, Église et État.