cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Evaluation von Informationssystemen zu Klimawandel und Gesundheit
Creators: name: Sturm, Diethard
Publisher: name: My University
Year: 2015
Subjects: subject: Anpassung an den Klimawandel
subject: Allgemeine Gesundheit
subject: Fachinformationssystem
subject: UV-Strahlung
subject: Hitze [Wetterlage]
subject: Pollenflug
subject: Ozonvorhersage
subject: Klima | Energie
subject: Gesundheit
subject: Climate | Energy
subject: Health

description: Der Klimawandel wirkt sich durch kontinuierliche Veränderungen, durch ein häufigeres und/oder verstärktes Auftreten von extremen Wetterereignissen und durch zunehmende Klimavariabilität auch auf die menschliche Gesundheit aus. Nationale Informations- und Frühwarnsysteme (UV-Index, Hitzewarnsystem, Pollenflug- und Ozonvorhersage) haben das Potenzial, Schutz- bzw. Anpassungsmaßnahmen durch die Bevölkerung auszulösen und somit die Gesundheit vor den Umweltfaktoren zu schützen. Mit Befragungen der Bevölkerung, Behörden und Einrichtungen des Umwelt- und Gesundheitswesens erfolgte die Evaluation der Informations- und Frühwarnsysteme. Auf dieser Basis wurde ein Kommunikationskonzept entwickelt.
Quelle: http://www.umweltbundesamt.de/
description: Der ⁠Klimawandel⁠ wirkt sich durch kontinuierliche Veränderungen, durch ein häufigeres und/oder verstärktes Auftreten von extremen Wetterereignissen und durch zunehmende ⁠Klimavariabilität⁠ auch auf die menschliche Gesundheit aus. Nationale Informations- und Frühwarnsysteme (UV-Index, Hitzewarnsystem, Pollenflug- und Ozonvorhersage) haben das Potenzial, Schutz- bzw. Anpassungsmaßnahmen durch die Bevölkerung auszulösen und somit die Gesundheit vor den Umweltfaktoren zu schützen. Mit Befragungen der Bevölkerung, Behörden und Einrichtungen des Umwelt- und Gesundheitswesens erfolgte die Evaluation der Informations- und Frühwarnsysteme. Auf dieser Basis wurde ein Kommunikationskonzept entwickelt.
Review of Modified AES for Lightweight Implementation for IoT Devices
Creators: name: Astha, Malviya
name: Rajeev, Thakur
Publisher: name: Zenodo
Year: 2024

description: The rapid proliferation of Internet of Things (IoT) devices necessitates robust yet lightweight security mechanisms to protect sensitive data. The Advanced Encryption Standard (AES) is widely recognized for its security and efficiency, but its conventional implementation can be too resource-intensive for IoT devices, which often have stringent constraints on power consumption, processing capacity, and memory. This review paper explores various modified AES algorithms tailored for lightweight implementation in IoT environments. We systematically analyze modifications aimed at reducing computational complexity, memory usage, and power consumption while maintaining or enhancing security levels. Our comprehensive survey covers optimization techniques such as algorithmic simplifications, hardware-friendly operations, and compact key management schemes. By evaluating these modified AES versions, we aim to provide insights into their suitability for different IoT applications, thereby guiding future research and development in securing IoT infrastructure effectively and efficiently.
Amastus edaphus Dyar 1913
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus edaphus

description: Amastus edaphus Dyar, 1913
Amastus edaphus Dyar, 1913a: 286.
TYPE LOCALITY. — Mexico, [Pueblo], Tehuacán.
TYPE SPECIMEN. — Holotype male no. 15 220 (USNM).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 298, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Amastus medica
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus medica

description: Amastus medica (Dognin, 1891)
Phaegoptera medica Dognin, 1891e: 242.
TYPE LOCALITY. — [Ecuador], [Loja], environs de Loja.
TYPE SPECIMEN. — Holotype female no. 30 395 (USNM).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 298, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Reflections on Immigration, Industry, and Innovation
Creators: name: Chan, Adrienne
Publisher: name: Unknown
Year: 2024
Subjects: subject: kerosene
subject: propane
subject: electricity
subject: vehicle manufacturing
subject: alternative energy
subject: 1973 oil crisis
subject: immigration
subject: transportation
subject: domestic labor

description: Adrienne Chan interviews father Ken Chan, who grew up in Hong Kong in the 1960s and immigrated to San Francisco in the 1970s. In Hong Kong, he reflects on the widespread use of kerosene, propane, and limited access to electricity. Domestic life involved manual labor, from handwashing clothes to boiling water for showers. Upon immigrating to the U.S., Ken observes the shift in energy practices, notably the introduction of hot running water, washing machines, and larger living spaces. He discusses the impact of the 1970s Arab Oil Embargo, which led to a shift towards energy-efficient vehicles and alternative energy research, contrasting it with the later American preference for SUVs and larger homes. Ken also notes his personal decisions to invest in solar heating and the fluctuating industrial interest in nuclear energy with his unique perspective in the vehicle manufacturing industry.
Burden of Disease Due to Traffic Noise in Germany
Creators: name: Hintzsche, Matthias
name: Myck, Thomas
name: Plaß, Dietrich
name: Tobollik, Myriam
name: Wothge, Jördis
Publisher: name: My University
Year: 2019
Subjects: Lärm
Fluglärm
Straßenverkehrslärm
Eisenbahn
Bundesrepublik Deutschland

description: Traffic noise is nearly ubiquitous and thus can affect the health of many people. Using the German noise mapping data according to the Directive 2002/49/EC of 2017 and exposure-response functions for ischemic heart disease, noise annoyance and sleep disturbance assessed by the World Health Organizationâ€Ìs Environmental Noise Guidelines for the European Region the burden of disease due to traffic noise is quantified. The burden of disease is expressed in disability-adjusted life years (DALYs) and its components. The highest burden was found for road traffic noise, with 75,896 DALYs when only considering moderate evidence. When including all available evidence, 176,888 DALYs can be attributable to road traffic noise. The burden due to aircraft and railway noise is lower because fewer people are exposed. Comparing the burden by health outcomes, the biggest share is due to ischemic heart disease (90%) in regard to aircraft noise, however, the lowest evidence was expressed for the association between traffic noise and ischemic heart disease. Therefore, the results should be interpreted with caution. Using alternative input parameters (e.g., exposure data) can lead to a much higher burden. Nevertheless, environmental noise is an important risk factor which leads to considerable loss of healthy life years. Quelle: https://www.mdpi.com
Amastus coprophora subsp. coprophora de Toulgoët 1986
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus coprophora
Amastus coprophora coprophora (herrich-Schäffer, [1853])

description: Amastus coprophora coprophora
(Herrich-Schäffer, [1853])
Phaegoptera coprophora Herrich-Schäffer, [1853] a: wrapper to pl. 15, fig. 63.
TYPE LOCALITY. — Venezuela.
TYPE SPECIMENS. — Undisclosed number of syntypes (ZIL; not found).
REMARK
A male specimen of A.coprophora labeled “ coprophora fig 63 ” in Herrich-Schäffer’s hand (ZMHB) could be a syntype. This specimen was illustrated as a “type” by Toulgoët (1986b: fig. 7).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 298, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Ritual dimension of union with Christ in Paul's thought
Creators: name: Chen, Yu
Publisher: name: The University of Edinburgh
Year: 2021
Subjects: ritual
union with Christ
participation
transformation

description: The study of the ritual (sacramental) aspect of participation in Christ has long been marginalised in the literature due to an anti-ritual bias that has several strands. Theologically, given the Biblical studies conducted under Protestant, word-centred, faith-focused principles in the past two centuries, any serious study of ritual practices in the nascent Christ movement would face suspicion of opus operatum. Intellectually, the rational approach to the studies of religion, developed during the Enlightenment period that so prized human reason, has led to the downplaying of rituals as superstitious practices, viewing the body as an unreliable source for truth, as opposed to the structure of the mind, where truth is located. Methodologically, the historical-critical approach practised by the Biblical studies guild and guided by text-centred and philologically focused principles, has resulted in the marginalisation of rituals in scholarship; ritual references are treated as a mere metaphor or a theological discourse. To give rituals their rightful place in the study of the New Testament, this study proposes that one needs to treat baptism and the Lord’s Supper in the New Testament as ritual practices rather than mere metaphor, with the aid of frameworks and theories developed in ritual studies. Chapter one of this study surveys the current scholarship on the topic and develops a new theoretical framework, the ritual transformation model, to study baptism and the Lord’s Supper. In chapters two and three, this study applies the ritual transformation model to study these two rituals, while chapters four and five address the exegetical issues of the relations amongst ritual, pistis, and “in Christ” language. In its conclusion, the study demonstrates that ritual and pistis are not antithetical to each other as body versus mind, that baptism and the Lord’s Supper are the two cardinal practices of the early Christ movement, and that the New Testament texts point to the religious experience of early Christ followers’ encounter with the risen messiah, an experience that is made accessible by the ritual performance.
Directional analysis of community wildfire evacuation capabilities
Creators: name: Kim, Amy M.
name: Beverly, Jennifer L.
name: Al Zahid, Abdullah
Publisher: name: The University of British Columbia
Year: 2026

description: Wildfires are a natural part of forest ecosystems, but sometimes pose a threat to communities. In Canada, when public safety is threatened by a wildfire encroaching into the wildland-urban interface (WUI), fire management agencies will recommend that local authorities evacuate the area. If a fire spreads quickly towards a community and egress capacity is insufficient, public safety can be compromised. This paper presents an interdisciplinary approach for assessing community directional vulnerabilities for wildfire evacuation, combining techniques from wildland fire science and transportation engineering. For a selection of communities in Alberta that were assessed as being potentially vulnerable to wildfire, we explored the directional configuration of the transportation network in relation to a directional assessment of wildfire exposure. We first plotted the viable fire pathways and transportation facility characteristics, and then compared estimated fire encroachment times against estimated community egress times, directionally around each community to show evacuation vulnerabilities. Our results show that some communities, mainly within the Boreal Forest, Foothills and Rocky Mountain natural regions, have egress routes that are highly exposed to potential wildfire encroachment. Our findings also indicate that the evacuation timing for some larger communities needs attention, given relationships between estimated fire travel times and evacuation times. The results can be used to inform evacuation preparedness planning and proactive mitigation efforts.
Amastus porioni Toulgoet 1981
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus porioni

description: Amastus porioni Toulgoët, 1981
Amastus porioni Toulgoët, 1981a: 2.
TYPE LOCALITY. — Ecuador, [Azuay], Route Gualaceo à Mendez, Km 49.
TYPE SPECIMEN. — Holotype male (MNHN).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 298, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Implementation of Digital Twin in Actual Production: Intelligent Assembly Paradigm for Large-Scale Industrial Equipment
Creators: name: Ding, Huaqiu
name: Zhao, Lizhong
name: Yan, Jihong
name: Feng, Hsi-Yung
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2023

description: The assembly process of large-scale and non-standard industrial equipment poses significant challenges due to its inherent scale-related complexity and proneness to errors, making it difficult to ensure process cost, production cycle, and assembly accuracy. In response to the limitations of traditional ineffective production models, this paper aims to explore and propose a digital twin (DT)-based technology paradigm for the intelligent assembly of large-scale and non-standard industrial equipment, focusing on both the equipment structure and assembly process levels. The paradigm incorporates key technologies that facilitate the integration of virtual and physical information, including the establishment and updating of DT models for assembly structures using actual data, the assessment of structural assemblability based on DT models, the planning and simulation of assembly processes, and the implementation of virtual commissioning technology tailored to the actual assembly process. The effectiveness of the proposed paradigm is demonstrated through a case study involving the actual assembly of a large-scale aerodynamic experimental equipment. The results confirm its ability to provide valuable technical support for the design, evaluation, and optimization of industrial equipment assembly processes. By leveraging the DT-based methodological system proposed in this paper, significant improvements in the transparency and intelligence of industrial equipment production processes can be achieved.
Verified transformations for convex programming
Creators: name: Fernández Mir, Ramon
Publisher: name: The University of Edinburgh
Year: 2024
Subjects: theorem proving
formal verification
proof assistants
Lean
convex optimization
convex programming

description: This thesis is concerned with developing and enhancing several components of CvxLean, a convex optimization modeling framework based on the mechanical proof assistant Lean 4. Convex programming studies the class of optimization problems that are either convex (convex objective function and feasible set) or equivalent to a convex problem. In practice, solvers expect the input to be in conic form, a low-level representation of the problem. Transforming a problem to an equivalent problem in conic form is not straightforward. It often requires several steps and uses properties of the functions involved in the problem in nontrivial ways. This is exactly the process that we formally verify in this work. The main transformation we verified is the "DCP transformation" step. This required formalizing and extending disciplined convex programming (DCP), a popular technique to transform problems into conic form. It works by iteratively replacing applications of well-understood functions with new variables and conic constraints. In our development, each replacement is augmented with proof obligations that are then combined to produce an overall proof of equivalence between the starting problem and its conic form counterpart. DCP requires problems to follow a strict set of rules. Often, users need to adjust how they write problems to follow these rules. Instead, we propose an automated and verified "pre-DCP transformation" step using an e-graph-based rewriting system. This procedure explores the space of equivalent problems and finds a sequence of rewrites to transform initial user problems into DCP-compliant forms. The applicability of the methods that we describe throughout the thesis to real-world problems is backed by a number of examples and case studies.
Amastus nebulosus Toulgoet 1986
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus nebulosus

description: Amastus nebulosus Toulgoët, 1986
Amastus nebulosus Toulgoët, 1986b: 59.
TYPE LOCALITY. — Venezuela, Aragua, Route Maracay à Choroni.
TYPE SPECIMEN. — Holotype male (MNHN).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 298, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Towards the design and construction of self-replicating RNA nanostructures
Creators: name: Rubert, David
Publisher: name: TU Dortmund
Year: 2024
Subjects: subject: RNA
subject: Self-replicating RNA
subject: Cell-free
subject: pRNA
subject: 570
subject: 540
subject: RNS

description: The transition from an RNA-based world to DNA as the primary genetic material is a pivotal topic in origin-of-life research. This study aims to prototype a hybrid genome system combining DNA and RNA, capable of self-replication and evolution, initially in vitro and potentially in vivo. Using Qß replicase, segmented RNA genomes were synthesized, incorporating the Phi29 phage pRNA for self-assembly into nanorings. The replication efficacy of these replicons was evaluated both independently and in coupled assembly-replication reactions, with Qß chosen for its high amplification efficiency and template versatility. To mitigate the challenge of parasite RNA formation, which depletes essential replication components, a water-emulsion system was employed. The modular assembly of replicons into nanorings was further investigated, with a focus on system reproducibility and the effect of Mg2+ concentrations on nanoring stability. The final goal is to integrate self-replication with self-assembly, thereby creating a segmented, modular RNA genome for in vitro genetic information storage. This work addresses key challenges and advancements in developing synthetic self-replication systems for eventual genomic transplantation in E. coli.
Prüfkriterien für die Überwachung von Gaspendelsystemen
Creators: name: Pannier, Karen
name: Mante, Hilmar
Publisher: name: My University
Year: 2015

description: Gaspendelsysteme sind Einrichtungen, die in vielen Bereichen der Industrie und Wirtschaft eingesetzt werden, um diffuse Emissionen flüchtiger organischer Stoffe zu vermeiden. Diese Systeme müssen regelmäßig auf Funktion und Dichtheit geprüft werden. Diese Prüfungen werden im Bereich von Tanklagern und Tankstellen beim Umschlag von Ottokraftstoff und Rohbenzin mit der neu erstellten Richtlinie VDI 2291 [1] geregelt. Diese konkretisiert den Stand der Technik von Gaspendelsystemen im Geltungsbereich der 20. Bundes-Immissionsschutzverordnung (20.BImSchV).
Quelle: http://www.technische-sicherheit.de
Direct de/carboxylation of cannabidiolic acid (CBDA) and cannabidiol (CBD) from hemp plant material under supercritical CO2
Creators: name: Gao, Bao-Chang
name: Sun, Yu-Feng
name: Tian, Yuan
name: Shi, Yu
name: Zhang, Zhi-Guo
name: Mao, Guo-Liang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Many organic reactions rely on CO2 sources to generate important structural units and valuable chemicals. In this study, we compared the effects of cannabidiol (CBD) and cannabidiolic acid (CBDA) on the supercritical CO2 (scCO2)-induced de/carboxylation reaction. The results showed that CBD was directly carboxylated in the ortho-position to form CBDA with up to 62% conversion. Meanwhile, CBDA decarboxylation occurred on hemp plant material via varying composition. Mechanistic studies revealed that CBD carboxylation was influenced not only by the physical properties of scCO2, but also by the vegetable matrix.
Supplementary document for Ultra-broadband quadrature squeezing with thin-film lithium niobate nanophotonics - 5647113.pdf
Creators: name: Chen, Pao-Kang
name: Briggs, Ian
name: hou, songyan
name: Fan, Linran
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Additional measurement and simulation
Development of natural perfume as potential fungicide candidates: construction and biological evaluation of vanillin analogs bearing the 1,3,4-oxadiazole/1,3-thiazolidin-4-one fragments
Creators: name: Zhang, Cheng-Ran
name: Wei, Si-Qi
name: Zhi, Xiao-Yan
name: Shi, Hong-Cheng
name: Liang, Jing
name: Hao, Xiao-Juan
name: Cao, Hui
name: Yang, Chun
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Two series of vanillin derivatives containing 1,3,4-oxadiazole and 1,3-thiazolidin-4-one scaffolds were prepared and evaluated for their antifungal activity. The results revealed that compounds 6j (29.73 μg/ml) and 7a (38.15 μg/ml) displayed excellent inhibitory activity against the spore of Fusarium solani. The inhibitory activity of compound 7d (10.53 μg/ml) against the spore of Alternaria solani was more than 42-fold that of vanillin. Compound 7a (37.54 μg/ml) showed better antifungal activity against the spore of B. cinerea than positive controls. The cytotoxicity assay confirmed that compounds 6k, 7a, and 7d showed good selectivity and less toxicity to normal mammalian cells.
Prevalence of virulence determinants among HA-MRSA and CA-MRSA isolates and its associated pathogenicity using Caenorhabdidtis elegans model
Creators: name: Sowndarya, Betsy
name: Prithika  Udhayakumar
name: Jeevan  Malaiyan
name: Balamurugan  Krishnaswamy
name: Krishnan, Padma
Publisher: name: F1000Research
Year: 2016

description: Background:
Methicillin-resistant Staphylococcus aureus (MRSA) has established itself as a major human pathogen causing both hospital and community acquired infections, especially due to its ability to express a myriad of virulence factors. There is paucity in data regarding the prevalence of virulence factors among MRSA isolates and its role in the pathogenesis and associated severity of infections from our part of the country.  Hence, the present study has been designed to use C. elegans, a simple nematode model for pathogenicity testing and to demonstrate the virulence potential of HA & CA-MRSA isolates.

Conclusion:
The present study documents the prevalence of various virulence factors among MRSA isolates. This preliminary study using C. elegans model has indicated higher pathogenesis and rapid killing of  HA-MRSA strains which showed higher prevalence of leukocidins (pvl, lukD, lukE) and enterotoxins (sea, sec, seg, sei) than CA-MRSA and could serve as  a pathogenesis model for S. aureus isolates.
Amastus bolivari Toulgoet 1990
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus bolivari

description: Amastus bolivari Toulgoët, 1990
Amastus bolivari Toulgoët, 1990c: 61.
TYPE LOCALITY. — Venezuela, Bolivar, Route El Dorado à S[an]ta Elena PK 118.
TYPE SPECIMEN. — Holotype male (MNHN).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 298, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Confirmation of silent mutations in the rpoB gene locus of M. tuberculosis isolates using pyrosequencing and phenotypic DST
Creators: name: Nilma Hirani
name: Joshi, Ameeta
name: Ajbani, Kanchan
name: Rodrigues, Camilla
name: Rashmeet Kaur
name: Chowdhary, Abhay
Publisher: name: F1000Research
Year: 2016

description: More than 95% cases of rifampicin resistance in M.tuberculosis strains can be attributed to mutations in 81-bp hotspot region of rpoB gene locus called Rifampicin Resistance Determining Region. These mutations can be detected by rapid molecular diagnostic techniques such as Line Probe Assay (LPA), but detection of silent or noncanonical mutations on LPA may not necessarily confer rifampicin resistance and result in false rifampicin resistance reporting. These silent mutations can be confirmed by phenotypic Drug Sensitivity Testing (DST) and/or by DNA sequencing.

This study was undertaken to confirm the silent or noncanonical mutations using phenotypic DST (Gold standard) and pyrosequencing, a rapid real time method for sequencing small DNA segments by synthesis.

A total of 300 DNA extracts comprising of 101 silent/noncanonical mutation strains, 101 pan-sensitive, 96 MDR-TB and 02 rifampicin mono-resistant strains were processed for pyrosequencing following detection by LPA. Pyrosequencing was performed with sequence analysis mode of  PyroMark Q96 ID system (Qiagen, Valencia, CA). All 300 sputum concentrates were also processed for phenotypic DST, using solid and liquid culture methods. Pyrosequencing detected mutations in all 101 silent/noncanonical mutation strains, but 02 strains did not produce amino acid change and hence, no alteration in protein structure (true silent mutations). Maximum mutations were seen in 526 codon (35 strains) followed by 511 codon region (30 strains). Two novel mutations were reported: substitution in 529 codon CGA – CAA and 517-518 codon deletion. However, only 53/101 rifampicin resistant strains were rifampicin resistant by MGIT 960 and 59/101 by solid DST. This proves that low-level rifampicin resistance linked to specific rpoB mutations could be missed by phenotypic DST and this could be attributed to the critical concentration of rifampicin used. 101 pan-sensitive, 96 MDR-TB and 02 rifampicin mono-resistant strains used as controls were confirmed by pyrosequencing and showed 100% concordance with phenotypic DST.

Hence, to conclude, pyrosequencing is a confirmatory tool for detection of rifampicin resistance in silent or noncanonical mutation cases in M. tuberculosis and reiterates the fact that liquid DST may miss some rifampicin resistance conferring mutations compared to solid DST, further suggesting that the gold standard for rifampicin resistance be reconsidered.
Okanagan Waterways Past, Present and Future: Approaching Sustainability through Immersive Museum Exhibition
Creators: name: Dulic, Aleksandra
name: Thorogood, Miles
name: Sam, Marlowe
name: Correia, Maria
name: Alexis, Sarah
name: Armstrong, Jeannette C.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2023

description: This paper presents Waterways Past, Present and Future, a research project and exhibition in Okanagan Syilx territory, aimed at increasing awareness of the relationship between people and water towards catalyzing sustainable water practices. The exhibition’s multi-channel audio-visual media was designed to immerse, provoke, destabilize, transform and move visitors to take responsibility for water. Drawing on many ways of knowing and doing in the creative process, the exhibition opens different entry points to the research, thus encouraging an interdisciplinary and cross-cultural audience to engage with it. Waterways’ contribution to sustainability discourse lies in its empowerment of collaborative inquiry as a way of knowing, understanding and representing our world. The epistemological dimensions of the exhibit present multiplicities embedded in the social life of water, inviting dialogues, shaping cultural narratives and developing new forms of creativity. Through the sensual process of immersion and activation of lateral thinking, the exhibition facilitates connections across cultures, connections that act as agents for social transformation. Waterways’ experiential journey transcends our personal and dominant socio-cultural patterns, reaching beyond normative structures to new creative realms shared ethical space.
Identification of Bartonella spp and Rickettsia spp of human body lice from homeless people of Bogota D.C, Colombia
Creators: name: Márquez, Andrea Camila
name: Faccini-Martínez, Alvaro
name: López-Castillo, Christian
name: Hidalgo, Marylin
name: Cuervo, Claudia
Publisher: name: F1000Research
Year: 2016

description: Human body lice (Pediculus humanus humanus) is recognized as the vector of different pathogenic bacteria as Bartonella quintana and Rickettsia prowazekii, the etiological agents of trench fever and epidemic typhus, respectively, being these bacteria re-emerging pathogens in different countries.

Poor living conditions and limited access to public services are predisposing factors to increase high prevalence of body lice infestation in different populations such as homeless people.

In Bogota-Colombia, approximately 9.614 homeless people are living in unsanitary conditions. However, our country has no reports about the presence of louse-borne bacteria and infection caused by this. Therefore, the aim of this study was to establish the presence of Bartonella spp and Rickettsia spp in body lice collected from homeless people in Bogota.
Secofumitremorgins C and D, a pair of atropisomers from saltern-derived fungus Aspergillus fumigatus GXIMD00544
Creators: name: Zhang, Geng-Si
name: Li, Hai-Yan
name: Liang, Li-Fen
name: Fu, Chun-Qing
name: Yu, Qin
name: Liu, Kai
name: Su, Zhi-Wei
name: Zhou, Dong-Mei
name: Gao, Cheng-Hai
name: Xu, Xin-Ya
name: Liu, Yong-Hong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: A pair of atropisomers secofumitremorgins C (1a) and D (1b), together with fifteen known alkaloids (2-16), were isolated from a saltern-derived fungus Aspergillus fumigatus GXIMD00544. The structures of atropisomers 1a and 1b were elucidated by the detailed spectroscopic data, chemical reaction and quantum chemical calculations. Compounds 1 and 8 displayed antifungal spore germination effects against plant pathogenic fungus associated with sugarcane Fusarium sp. with inhibitory rates of 53% and 77% at the concentration of 100 µM, repectively. Atropisomers 1 also exhibited antifouling potential against Balanus amphitrite larval settlement with an inhibitory rate of 96% at the concentration of 100 µM.
Lycium barbarum polysaccharides regulate the gut microbiota to modulate metabolites in high-fat diet-induced obese rats
Creators: name: Fan, Yan-Na
name: Chi, Xi
name: Yan, Lu
name: Pu, Zhi-Yu
name: Yang, Jian-Jun
name: Zhang, Yan-Nan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Lycium Barbarum Polysaccharides (LBP) can benefit lipid parameters such as total cholesterol, triglyceride, and high-density lipoprotein levels and upregulate the level of Firmicutes, increase the diversity of gut microbiota and reduce metabolic disorders, finally relieving weight gain of obese rats. But it cannot reverse the outcome of obesity. Over 30 differential metabolites and four pathways are altered by LBP.
Macrophorins H and L, two new HMG-conjugate macrophorins from rihzospheric Penicillium sp. NX-05-G-3
Creators: name: Tang, Xiao-Long
name: Ran, Kai
name: Wang, Bo-Chu
name: Qu, Xian-You
name: Chen, Zhong-Zhu
name: An, Ya-Nan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Macrophorins H (4) and L (5), two rare HMG-conjugate macrophorins along with three known macrophorins (1-3), three DMOA-derived meroterpenoids (6-8) and two ergosterol derivates (9-10) were isolated from sterilized rice medium cultured Penicillium sp. NX-05-G-3. Their structures were elucidated by 1D and 2D NMR. The cytotoxicities of all compounds were evaluated, and compounds 1 and 2 showed extensive cytotoxicity against human cancer cell lines Hela, SCC15, MDA-MB-453 and A549, with IC50 values ranging from 17.6 to 32.8 µM.
Amastus flavicauda Rothschild 1909
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus flavicauda

description: Amastus flavicauda Rothschild, 1909
Amastus flavicauda Rothschild, 1909b: 278.
Amastus orosiana Seitz, 1925: 418. — Type locality: Costa Rica, [Cartago], Volcan Irazu. — Type specimens: Undisclosed number of syntypes (?)
TYPE LOCALITY. — Panama, Chiriqui.
TYPE SPECIMEN. — Described on 3 males and 10 females. We chose the male syntype with a white printed label “ Chiriqui, Panama.” / a white printed label “Rothschild Bequest B.M. 1939-1.” / a pink handwritten label “ Amastus flavicauda Type Rothsch[ild]” / a round red printed label “Type”, and designated it as lectotype. We have labeled it with a round blue label “ Lectotype ” and a white printed label “ Lectotype Amastus flavicauda ♂ by Vincent & Laguerre” (BMNH).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 299, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Periodic temperature changes drive the proliferation of self-replicating RNAs in vesicle populations
Creators: name: Salibi, Elia
name: Peter, Benedikt
name: Schwille, Petra
name: Mutschler, Hannes
Publisher: name: TU Dortmund
Year: 2023
Subjects: subject: Membrane biophysics
subject: Chemical origin of life
subject: Ribozymes
subject: RNA
subject: Synthetic biology
subject: 570
subject: 540

description: Growth and division of biological cells are based on the complex orchestration of spatiotemporally controlled reactions driven by highly evolved proteins. In contrast, it remains unknown how their primordial predecessors could achieve a stable inheritance of cytosolic components before the advent of translation. An attractive scenario assumes that periodic changes of environmental conditions acted as pacemakers for the proliferation of early protocells. Using catalytic RNA (ribozymes) as models for primitive biocatalytic molecules, we demonstrate that the repeated freezing and thawing of aqueous solutions enables the assembly of active ribozymes from inactive precursors encapsulated in separate lipid vesicle populations. Furthermore, we show that encapsulated ribozyme replicators can overcome freezing-induced content loss and successive dilution by freeze-thaw driven propagation in feedstock vesicles. Thus, cyclic freezing and melting of aqueous solvents – a plausible physicochemical driver likely present on early Earth – provides a simple scenario that uncouples compartment growth and division from RNA self-replication, while maintaining the propagation of these replicators inside new vesicle populations.
description: Nature communications;14
Supplementary document for Ultra-broadband quadrature squeezing with thin-film lithium niobate nanophotonics - 5647113.pdf
Creators: name: Chen, Pao-Kang
name: Briggs, Ian
name: hou, songyan
name: Fan, Linran
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Additional measurement and simulation
Amastus umber Rothschild 1909
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus umber

description: Amastus umber Rothschild, 1909
Amastus umber Rothschild, 1909b: 279.
Amastus lichyi Toulgoët, 1984a: 42. — Type locality: Venezuela, [Merida], Vallée de la Mucuy. — Type specimen: Holotype male (MNHN).
TYPE LOCALITY. — Venezuela, Merida.
TYPE SPECIMENS. — Described from 1 male and 4 female syntypes (BMNH; one of the female syntypes labeled TYPE).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 299, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Ribozyme-mediated RNA synthesis and replication in a model Hadean microenvironment
Creators: name: Salditt, Annalena
name: Karr, Leonie
name: Salibi, Elia
name: Le Vay, Kristian
name: Braun, Dieter
name: Mutschler, Hannes
Publisher: name: TU Dortmund
Year: 2023
Subjects: subject: Chemical origin of life
subject: Ribozymes
subject: Synthetic biology
subject: 570
subject: 540

description: Enzyme-catalyzed replication of nucleic acid sequences is a prerequisite for the survival and evolution of biological entities. Before the advent of protein synthesis, genetic information was most likely stored in and replicated by RNA. However, experimental systems for sustained RNA-dependent RNA-replication are difficult to realise, in part due to the high thermodynamic stability of duplex products and the low chemical stability of catalytic RNAs. Using a derivative of a group I intron as a model for an RNA replicase, we show that heated air-water interfaces that are exposed to a plausible CO2-rich atmosphere enable sense and antisense RNA replication as well as template-dependent synthesis and catalysis of a functional ribozyme in a one-pot reaction. Both reactions are driven by autonomous oscillations in salt concentrations and pH, resulting from precipitation of acidified dew droplets, which transiently destabilise RNA duplexes. Our results suggest that an abundant Hadean microenvironment may have promoted both replication and synthesis of functional RNAs.
description: Nature communications;14
Search for magnetic monopoles and stable particles with high electric charges in √s = 13 TeV pp collisions with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: Springer Berlin Heidelberg
Year: 2024

description: We present a search for magnetic monopoles and high-electric-charge objects using LHC Run 2 √ s = 13 TeV proton-proton collisions recorded by the ATLAS detector. A total integrated luminosity of 138 fb−1 was collected by a specialized trigger. No highly ionizing particle candidate was observed. Considering the Drell-Yan and photon-fusion pair production mechanisms as benchmark models, cross-section upper limits are presented for spin-0 and spin-1/2 magnetic monopoles of magnetic charge 1gD and 2gD and for highelectric-charge objects of electric charge 20 ≤ |z| ≤ 100, for masses between 200 GeV and 4000 GeV. The search improves by approximately a factor of three the previous cross-section limits on the Drell-Yan production of magnetic monopoles and high-electric charge objects. Also, the frst ATLAS limits on the photon-fusion pair production mechanism of magnetic monopoles and high-electric-charge objects are obtained.
Glycoside constituents from Cayratia geniculata
Creators: name: Cuong, Dang Viet
name: Hanh, Tran Thi Hong
name: Huong, Pham Thi Mai
name: Huong, Nguyen Thi
name: Quang, Tran Hong
name: Cuong, Nguyen Xuan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Using various chromatographic separations, six glycoside derivatives (1–6), including one new ent-labdane glucoside named cayratioside (1), were isolated from the methanol extract of Cayratia geniculata stems and leaves. Their structures were elucidated by detailed analysis of the 1D, 2D NMR, and HRESIQTOF mass spectra. The inhibitory effect of 1–6 on LPS-induced NO production in RAW264.7 cells was also evaluated. Among isolated compounds, 1 exhibited moderate activity with an IC50 value of 59.65 ± 1.85 µM.
Amastus affinis Rothschild 1909
Creators: name: Vincent, Benoît
name: Laguerre, Michel
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Amastus
Amastus affinis

description: Amastus affinis Rothschild, 1909
Amastus affinis Rothschild, 1909b: 278.
TYPE LOCALITY. — Peru, [Puno], Santo Domingo, Carabaya.
TYPE SPECIMEN. — Described on 10 males and 8 females. We chose the male syntype with a white printed label “S[anto] Domingo, Carabaya, 6000 ft, July 02 Dry s. (G. Ockenden)” / two white printed labels “Rothschild Bequest B.M. 1939-1.” / a pink handwritten label “ Amastus affinis Type Rothsch[ild]” / a round red printed label “Type”, and designated it as lectotype. We have labeled it with a round blue label “ Lectotype ” and a white printed label “ Lectotype Amastus affinis ♂ by Vincent & Laguerre” (BMNH).
description: Published as part of Vincent, Benoît & Laguerre, Michel, 2014, Catalogue of the Neotropical Arctiini Leach, [1815] (except Ctenuchina Kirby, 1837 and Euchromiina Butler, 1876) (Insecta, Lepidoptera, Erebidae, Arctiinae), pp. 137-533 in Zoosystema 36 (2) on page 299, DOI: 10.5252/z2014n2a1, http://zenodo.org/record/5395344
Prevalence of pneumococcal serotypes in adults ≥ 50 yrs of age
Creators: name: Wattal, Chand
name: Goel, Neeraj
name: S.P. Byotra
Publisher: name: F1000Research
Year: 2016

description: Background
Current study was undertaken to determine the antibiotic resistance pattern and the coverage of the PPV23 in the elderly population.

Conclusions:
Our study shows different pattern of susceptibility in S. pneumoniae in contrast to previously reported. The modest coverage of S. pneumoniae serotypes by PPV23 vaccine in Indian adult population and prevalence of diverse non vaccine makes it compelling to carry further studies from different regions of  India to assess their efficacy.
Exploring BIM Implementation Challenges in Complex Renovation Projects: A Case Study of UBC’s BRDF Expansion
Creators: name: Zadeh, Puyan A.
name: Han, Seungho
name: Staub-French, Sheryl
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2023

description: Renovation of existing buildings pose unique challenges to the projects, especially when facilities must remain operational during construction. Building Information Modeling (BIM) methods offer a potential solution by enhancing project management and coordination. Nevertheless, comprehensive case study research on BIM implementation challenges and benefits in renovation projects is lacking. This research addresses this gap through an ethnographic investigation of BIM implementation in a complex renovation project. The ethnographic methods involved direct observation of project meetings, active engagement in all project communications, and access to project data resources. Additionally, surveys and expert interviews with key decision-makers were conducted. The findings reveal how BIM implementation streamlined project management and improved communication, decision making, and output quality, despite limited prior BIM expertise among the major stakeholders. Challenges included a lack of BIM skills, absence of standardized practices, and unclear data management. Furthermore, valuable lessons were identified, including that the necessity of BIM requirements and proper procurement methods encompassing the entire project workflow, formalizing information exchange, preventing information fragmentation, facilitating model accessibility, and ensuring clarity in model detail and content are crucial for project success. This research sheds light on the potential of BIM in renovation projects and highlights key considerations for successful implementation.
»Going Dark«. Data tracking and data access at European level
Creators: name: Siems, Renke
Publisher: name: Zenodo
Year: 2024
Subjects: state surveillance
risk solutions
academic freedom

description: It sounds as if Brussels wants to become a cyberpunk metropolis: an expert group that is not allowed to be called that so that you can't know who its members are. Data access to devices, services and infrastructures whenever the »security« deems it necessary. Influence on industry standards so that this is always possible in real time. If not, it is regrettable that vulnerabilities will have to be exploited and penalties imposed on those who do not »co-operate«. What even the name - Going Dark - makes it look like the scorched no-man's land between Neuromancer and V for Vendetta, has an administrative designation: »High-Level Group on Access to Data for Effective Law Enforcement«. The far-reaching proposals of this EU working group were rated as „impressive and forward-looking“ by the Hungarian government and are to become the focus of the current Council Presidency. And always at the centre of this development, in past and present: scientific infrastructures.

This text is a machine-based translation of the weblog article »Going Dark. Datentracking und Datenzugriff auf europäischer Ebene« in order to provide easier access for non-German speaking interested parties, also the german language quotes were therefore transferred. Consider this version a »post-print derivative« and please refer to the original in case of references or citations: Siems, Renke (2024): „Going Dark“. Datentracking und Datenzugriff auf europäischer Ebene. In: Verantwortungsblog. https://zevedi.de/going-dark-datentracking-und-datenzugriff-auf-europaischer-ebene/. DOI: https://doi.org/10.60805/p7w9-d268