cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
3D printing applications in Ophthalmology
Creators: name: Αντωνιάδου, Χριστίνα Αντωνίου
Publisher: name: Aristotle University of Thessaloniki
Year: 2023
Subjects: Τρισδιάστατη εκτύπωση
Οφθαλμολογία
Εφαρμογές
3d printing
Ophthalmology
Applications

description: 3D printing, is a term referred to a number of manufacturing techniques that utilize digital data obtained by 3D scanning or computer-aided design software in order to generate 3D physical objects. While actual applications of 3D printing in medicine used to be considered a product of fiction, today 3D printing is used to produce medical implants, aid in surgical procedure planning and has a part in medical education and research. In the world of ophthalmology, a field of medicine that traditionally integrates new technology in its practice, these advancements are having a major impact and are altering everyday practice on so many levels. The purpose of this review, is to inform the readers about the areas of ophthalmology in which 3D printing applications are found and shed light to the impact of 3D printing in these areas. By raising awareness of 3d printing applications and their possibilities this review article could potentially be of use in clinicians, researchers and optometrists when searching for a solution in a complex problem.
description: Η τρισδιάστατη εκτύπωση είναι ένας όρος που αναφέρεται σε έναν αριθμό κατασκευαστικών τεχνικών που χρησιμοποιούν ψηφιακά δεδομένα που λαμβάνονται από τρισδιάστατη σάρωση ή λογισμικό σχεδιασμού με τη βοήθεια υπολογιστή για τη δημιουργία τρισδιάστατων φυσικών αντικειμένων. Ενώ οι πραγματικές εφαρμογές της τρισδιάστατης εκτύπωσης στην ιατρική θεωρούνταν προϊόν μυθοπλασίας, σήμερα η τρισδιάστατη εκτύπωση χρησιμοποιείται για την παραγωγή ιατρικών εμφυτευμάτων, βοηθά στον προγραμματισμό χειρουργικών επεμβάσεων και συμμετέχει στην ιατρική εκπαίδευση και έρευνα. Στον κόσμο της οφθαλμολογίας, έναν τομέα της ιατρικής που παραδοσιακά ενσωματώνει τη νέα τεχνολογία στην πρακτική του, αυτές οι εξελίξεις έχουν σημαντικό αντίκτυπο και αλλάζουν την καθημερινή πρακτική σε τόσα πολλά επίπεδα. Σκοπός αυτής της ανασκόπησης, είναι να ενημερώσει τους αναγνώστες για τους τομείς της οφθαλμολογίας στους οποίους εντοπίζονται εφαρμογές τρισδιάστατης εκτύπωσης και να ρίξει φως στον αντίκτυπο της τρισδιάστατης εκτύπωσης σε αυτούς τους τομείς. Αυξάνοντας την ευαισθητοποίηση σχετικά με τις εφαρμογές τρισδιάστατης εκτύπωσης και τις δυνατότητές τους, αυτό το άρθρο ανασκόπησης θα μπορούσε ενδεχομένως να είναι χρήσιμο σε κλινικούς ιατρούς, ερευνητές και οπτομέτρες όταν αναζητούν λύση σε ένα περίπλοκο πρόβλημα.
Associations of dietary intake patterns identified using reduced rank regression with markers of arterial stiffness among youth with type 1 diabetes
Creators: name: Jaacks, L M
name: Dabelea, D
name: Liese, A D
name: Black, M H
name: Merchant, A T
name: Crandell, J L
name: Mayer-Davis, E J
name: Urbina, E M
name: Lamichhane, A P
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Youth with type 1 diabetes (T1DM) are at substantially increased risk for adverse vascular outcomes, but little is known about the influence of dietary behavior on cardiovascular disease (CVD) risk profile. We aimed to identify dietary intake patterns associated with CVD risk factors and evaluate their impact on arterial stiffness (AS) measures collected thereafter in a cohort of youth with T1DM.
Rechtliche und organisatorische Aspekte aus Betreibersicht
Creators: name: Ebert, Barbara
Publisher: name: Zenodo
Year: 2023
Subjects: NFDI4Biodiversity
Rechtsfragen

description: Mit dem Portal "Lebendiger Atlas Natur Deutschland" wird das Ziel verfolgt, Verbreitungsdaten über alle Arten in Deutschland verfügbar zu machen. Als Datengeber sind hier nicht die Datenerzeuger:innen selbst angesprochen, sondern Datenarchive und andere Intermediäre, die entsprechende Datensammlungen vorhalten. Ob Daten von diesen Betreibern weitergegeben werden können (und wenn ja: welche), hängt von den Vereinbarungen ab, die sie mit den Datenerzeuger:innen getroffen haben. Der Lebendige Atlas ist also Teil einer längeren Liefer- und Verwertungskette für Daten. Der Impulsvortrag thematisiert ausgewählte Rechtsfragen, die aus Betreibersicht zu klären sind.
description: Impulsvortrag im Rahmen des Workshops "Lebendiger Atlas Natur Deutschlands" am 30. und 31. März 2023 in Leipzig. Die Arbeit der Autorin und der Workshop sind finanziert von der Deutschen Forschungsgemeinschaft im Rahmen des Projekts NFDI4Biodiversity (Projektnummer 442032008).
title: The synthesis and biological evaluation of natural and unnatural cyclopentenone prostanoids
Creators: name: J. Snape, Timothy
Publisher: name: University of Liverpool Repository
Year: 2023

description: Research into the synthesis and biological properties of the cyclopentenone prostaglandins has become the focus of many research groups over the past few years. The ability for cyclopentenone prostaglandins, for example prostaglandin AI. to reduce virus yields and inflammation, both in vitro and in vivo, and to act as anticancer agents in vitro has made them important biological targets. o .••",~COOH OH prostaglandin Al In view of this, a great deal of work is currently being undertaken towards the preparation of cyclopentenone prostaglandin analogues, in the hope of harnessing the innate biological activity of this system. Part of the ongoing research into the cyclopentenone prostaglandins is the work currently being undertaken at The University of Liverpool, and this Ph.D. thesis is part of the contribution made by the Roberts' group. This thesis begins with an introductory section, Chapter 1, outlining the background and biological properties of the natural prostaglandins, along with examples of their chemical syntheses and some of the work carried out on other, related cyclopentenone-based natural products. Chapter 2 goes on to elaborate upon the biological results obtained during the course of this Ph.D., the synthesis of various prostaglandin analogues and the discussion of these results. The latter part of Chapter 2 describes the synthesis and ultimately the revision of stereochemistry of a natural product isolated from ascomycete strain A23-98. It has been shown that a-iodo-cyclopentenone 160, generated in 7 steps from Dribose, can undergo a palladium-catalysed Stille reaction, followed by deprotection of the masked diol, to reveal the natural product syn-163. n-ribose steps i) (PhCNhPdCI2' CuI, AsPh] HO""' ..~ -~ HO,)JT~ syn-l63 (Z)-tributylpropenylstannane 160 ii) PPTS, MeOH Following the synthesis it was subsequently discovered that the geometry of the sidechain is cis, as shown in syn-163, and not trans as proposed by NMR studies and correlation to similar natural products. Finally, Chapter 3 describes the experimental details associated with the compounds prepared throughout this thesis, followed by a reference section giving relevant citations in the chemical literature.
Timing of complementary food introduction and age at diagnosis of type 1 diabetes: the SEARCH nutrition ancillary study (SNAS)
Creators: name: Norris, J M
name: Pettitt, D J
name: Rodriguez, B L
name: Mayer-Davis, E J
name: Fangman, M T
name: Crandell, J
name: Dabelea, D
name: Crume, T L
name: O'Connor, R
name: Dolan, L
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The association between timing of complementary food introduction and age at diagnosis of type 1 diabetes was investigated among 1077 children in the SEARCH for Diabetes in Youth study. Age at diagnosis was 5-month earlier for children introduced to sugar-sweetened beverages (SSB) in the first 12 months of life compared to those who were not (9.0 ± 0.2 vs. 9.5 ± 0.1; p=0.02), independent of HLA-risk status. Analyses stratified by HLA-risk status found that children with a high risk HLA genotype had an earlier age at diagnosis if they were introduced to fruit juice in the first year of life (mean age of diagnosis=9.3 ± 0.1, 9.1 ± 0.1 and 9.6 ± 0.2 for introduction at ≤ 6 months, between 7 and 11 months, and ≤12 months, respectively; p=0.04). Introduction of SSB in the first year of life may accelerate onset of type 1 diabetes independent of HLA-risk status.
Anomalous transport in periodic photonic chains with designed loss
Creators: name: Peshko, I.
name: Slepyan, G. Ya.
name: Mogilevtsev, D.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Here we show that a coherent random walk in a perfectly periodic chain of bosonic modes with designed loss can exhibit a variety of different anomalous transfer regimes in dependence on the initial state of the chain. In particular, for any given finite initial time-interval there is a set of initial states leading to a hyperballistic transport regime. Also, there are initial states allowing one to achieve a subdiffusive regime or even localization for a given time-interval, or change an asymptotic long-time diffusion rate. We show how these anomalous transport regimes can be practically realized in a laser-written network of single-mode waveguides in balk glass or how a planar system of coupled single-mode waveguides can be realized with an integrated photonic platform.
description: It is a published version
The impact of token manipulation in Natural Language Generation systems
Creators: name: Vedd, Nihir
Publisher: name: Imperial College London
Year: 2024

description: In recent years, Natural Language Generation (NLG) systems have achieved human-level performance on a variety of tasks, primarily using encoder-decoder or decoder-only architectures. Training these decoders on downstream data has been enhanced by techniques that manipulate token presence. For instance, BART employs methods such as token masking, sentence permutation, and token deletion to corrupt inputs. We introduce the term "token manipulation" to describe these methods that alter token presence to impact language models. Our hypothesis posits that token manipulation can improve NLG system performance, which we classify into input-side and output-side approaches. Input-side manipulation occurs before a model processes inputs, whereas output-side manipulation happens after. Our research includes novel token manipulation strategies for both uni-modal and multi-modal tasks. Initially, we explored masking during fine-tuning, noting substantial improvements over baseline models. Encouraged by input-side manipulation’s success, we tested output-side manipulation by applying artificial tokenisations to an auxiliary decoder, which also yielded significant enhancements without increasing parameter count or computational complexity. Furthermore, we applied input-side token manipulation to a multi-modal Visual Question Generation (VQG) task, introducing three new strategies for token imputation during modeling, achieving significant performance gains. Combining our input-side and output-side models resulted in our most effective model, showing a 14.5% increase in metrics across various uni-lingual generative tasks. In translation benchmarks, we observed a 2.4 BLEU-4 improvement in IWSLT DE-EN, 0.8 in WMT '16 DE-EN, and 1.6 in WMT '16 EN-RO. Our VQG model surpassed state-of-the-art results by more than 9 BLEU-4 points at publication.
Slow early growers have more muscle in relation to adult activity: evidence from Cebu, Philippines
Creators: name: McDade, T W
name: Workman, M
name: Adair, L S
name: Kuzawa, C W
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Adult skeletal muscle mass (SMM) protects against type 2 diabetes but little is known about its developmental antecedents. We examined whether pace of early weight gain predicted adult SMM in a birth cohort from Cebu City, Philippines. Additionally, we examined whether increases in SMM associated with adult muscle-building exercise varied according to early growth.
The double burden of under- and overnutrition and nutrient adequacy among Chinese preschool and school-aged children in 2009–2011
Creators: name: Wang, D
name: Wang, Z
name: Su, C
name: Du, S
name: Popkin, B M
name: Piernas, C
name: Zhang, B
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Coincident with economic development, China has experienced a dramatic transition from undernutrition to overweight/obesity over the last few decades. We aimed to explore the burden of under- and overnutrition and nutrient adequacy among 2-12 y-old Chinese children.
Supplementary document for Electric Field Measurement of Femtosecond Time-Resolved Four-Wave Mixing Signals in Molecules - 5963485.pdf
Creators: name: Walz, Francis
name: Pandey, Siddhant
name: Tan, Liang
name: Shivaram, Niranjan
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Supplemental document containing information on electric field retrieval and lineouts of the measured electric field
The d-separation criterion in Categorical Probability
Creators: name: Fritz, Tobias
name: Klingler, Andreas
Publisher: name: arXiv
Year: 2022
Subjects: subject: Statistics Theory (math.ST)
subject: Logic in Computer Science (cs.LO)
subject: Category Theory (math.CT)
subject: Probability (math.PR)
subject: Machine Learning (stat.ML)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: Primary: 18M30, 62A09, Secondary: 18M35, 60A05, 62D20

description: The d-separation criterion detects the compatibility of a joint probability distribution with a directed acyclic graph through certain conditional independences. In this work, we study this problem in the context of categorical probability theory by introducing a categorical definition of causal models, a categorical notion of d-separation, and proving an abstract version of the d-separation criterion. This approach has two main benefits. First, categorical d-separation is a very intuitive criterion based on topological connectedness. Second, our results apply both to measure-theoretic probability (with standard Borel spaces) and beyond probability theory, including to deterministic and possibilistic networks. It therefore provides a clean proof of the equivalence of local and global Markov properties with causal compatibility for continuous and mixed random variables as well as deterministic and possibilistic variables.
description: 42 pages, v2: more examples and an extended introduction, v3: corrected typo in Def. 4
Multi-wavelength observations of 3C 279 during the extremely bright gamma-ray flare in 2014 March-April
Creators: name: Paliya, Vaidehi S.
name: Sahayanathan, S.
name: Stalin, C. S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The well studied blazar 3C 279 underwent a giant $γ$-ray outburst in 2014 March-April. The measured $γ$-ray flux (1.21 $\pm$ 0.10 $\times$ 10$^{-5}$ ph cm$^{-2}$ s$^{-1}$ in 0.1-300 GeV energy range) is the highest detected from 3C 279 by Fermi Large Area Telescope. Hour scale $γ$-ray flux variability are observed, with a flux doubling time as short as 1.19 $\pm$ 0.36 hours detected during one flare. The $γ$-ray spectrum is found to be curved at peak of the flare suggesting low probability of detecting very high energy (VHE; E $>$ 100 GeV) emission, which is further confirmed by the Very Energetic Radiation Imaging Telescope Array System observations. The $γ$-ray flux increased by more than an order in comparison to low activity state and the flare consists of multiple sub-structures having fast rise and slow decay profile. The flux enhancement is seen in all the wavebands though at a lesser extent compared to $γ$-rays. During the flare, a considerable amount of the kinetic jet power gets converted to $γ$-rays and the jet becomes radiatively efficient. A one zone leptonic emission model is used to reproduce the flare and we find increase in the bulk Lorentz factor as a major cause of the outburst. From the observed fast variability, lack of VHE detection, and the curved $γ$-ray spectrum, we conclude that the location of the emission region cannot be far out from the broad line region (BLR) and contributions from both BLR and torus photons are required to explain the observed $γ$-ray spectrum.
description: 42 pages, 8 figures, 7 tables, to appear in the Astrophysical journal
Seismic assessment models for cross-laminated timber buildings
Creators: name: Junda, Eknara
Publisher: name: Imperial College London
Year: 2024

description: Multi-storey cross-laminated timber (CLT) buildings are being increasingly used around the globe. The growing popularity of CLT construction is due to its multiple advantages relative to traditional materials (like steel or concrete), which include less environmental impact, exceptional structural performance, and decreased construction time and expenses. Moreover, CLT is an attractive option in places prone to earthquakes because of the high resistance to lateral forces as a lateral force-resisting system. Due to these factors, the seismic behaviour of CLT structures has been extensively investigated via experimental and numerical studies during the last 20 years. Interestingly, due to the novelty of CLT buildings, there is a paucity of predictive models to estimate seismic demands in mid-to high-rise CLT structures. This is especially true for simple models that may be used for preliminary design evaluations or regional seismic assessments. The main objective of this thesis is to exploit the benefits and evaluate several Machine Learning (ML) models for estimating various seismic demands of CLT structures covering inelastic deformations, shear forces, and floor accelerations. A comprehensive database of 69 CLT structures, encompassing a diverse set of structural configurations, has been created. The structures, spanning mid-rise to tall timber buildings, are subjected to a collection of 1656 ground motions and used to create the training and testing datasets. Afterwards, efficient features are identified using ML-based feature selection algorithms, and regression models are developed to estimate seismic demands in multi-storey CLT structures. Furthermore, the study proposes a stochastic-based LCA framework for estimating the environmental impact of multi-storey CLT buildings. The proposed framework considers the impact of two critical factors: structural deterioration and seismic hazard, which are expected to influence the structural behaviour of CLT buildings substantially and consequently impact the outcomes of their LCA analysis. Finally, suggestions for future work are outlined.
Simple superelliptic Lie algebras
Creators: name: Cox, Ben
name: Guo, Xiangqian
name: Lu, Rencai
name: Zhao, Kaiming
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: Let $m\in N$, $P(t)\in C[t]$. Then we have the Riemann surfaces (commutative algebras) $R_m(P)=C[t^{\pm1},u | u^m=P(t)]$ and $S_m(P)=C[t , u| u^m=P(t)].$ The Lie algebras $\mathcal{R}_m(P)=Der(R_m(P))$ and $\mathcal{S}_m(P)=Der(S_m(P))$ are called the $m$-th superelliptic Lie algebras associated to $P(t)$. In this paper we determine the necessary and sufficient conditions for such Lie algebras to be simple, and determine their universal central extensions and their derivation algebras. We also study the isomorphism and automorphism problem for these Lie algebras.
description: Corrections on Corollaries 15 and 16
How Much Lookahead is Needed to Win Infinite Games?
Creators: name: Klein, Felix
name: Zimmermann, Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: Formal Languages and Automata Theory (cs.FL)
subject: FOS: Computer and information sciences

description: Delay games are two-player games of infinite duration in which one player may delay her moves to obtain a lookahead on her opponent's moves. For $ω$-regular winning conditions it is known that such games can be solved in doubly-exponential time and that doubly-exponential lookahead is sufficient. We improve upon both results by giving an exponential time algorithm and an exponential upper bound on the necessary lookahead. This is complemented by showing EXPTIME-hardness of the solution problem and tight exponential lower bounds on the lookahead. Both lower bounds already hold for safety conditions. Furthermore, solving delay games with reachability conditions is shown to be PSPACE-complete. This is a corrected version of the paper https://arxiv.org/abs/1412.3701v4 published originally on August 26, 2016.
CYP2C9 genotype and pharmacodynamic responses to losartan in patients with primary and secondary kidney diseases
Creators: name: Falk, Ronald J.
name: Goldstein, Joyce A.
name: Candiani, Corina
name: Hilliard, Tandrea
name: Blaisdell, Joyce
name: Joy, Melanie S.
name: Boyette, Tammy
name: Hu, Yichun
name: Dornbrook-Lavender, Kimberly
name: Hogan, Susan L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Losartan is used for anti-proteinuric as well as blood pressure effects in chronic kidney disease (CKD). It is metabolized by cytochrome P450 2C9 to active E-3174. Single nucleotide polymorphisms in CYP2C9 that reduce catalytic activity could reduce clinical benefits. The study aims were to determine whether CYP2C9 variant alleles (*2 and *3) altered urinary protein excretion, glomerular filtration rate, and blood pressure in Caucasians prescribed losartan. Differences between baseline and six-month follow-up outcomes were compared by CYP2C9 genotypes in 59 patients using unpaired T-test or Mann Whitney U test. Primary renal disease patients had a trend toward less favorable antiproteinuric response (−31.7±156 vs −125±323%; p=0.123) when carrying variant alleles. Patients with secondary renal diseases had less favorable diastolic blood pressure (9.8±16.0 mm Hg vs −3.2±10.6 mm Hg; p=0.043) and systolic blood pressure (16.2±27.1 mm Hg vs −5.5±17.5 mm Hg; p=0.044) with CYP2C9 variants. Preliminary results suggest a possible influence of CYP2C9 genotype on proteinuria and blood pressure in Caucasian CKD patients treated with losartan.
JETIR2209292.pdf
Creators: name: BHAT, RAMDAS
Publisher: name: figshare
Year: 2022
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 111504 Pharmaceutical Sciences
subject: Pharmacology
subject: 111502 Clinical Pharmacology and Therapeutics
subject: 111501 Basic Pharmacology

description: The present study was conducted to examine the anti-inflammatory activity of aqueous fruits extract of Malus sylvestris using suitable experimental models. Wister rats were divided into 5 groups of n=6 each using Aspirin (300 mg/kg, p.o) as the standard drug. The Aqueous extract of Malus sylvestris was given at three doses of 200 mg/kg, 400 mg/kg and 800 mg/kg p.o. in distilled water respectively. Prepared extract was administered orally once daily for 7 consecutive days one hour prior to the administration of 0.1ml carrageenan injection in sub-plantar region. The volume of the rat paw was measured at the end of 7th day. The present study reveals that the aqueous extract of Malus sylvestris at the doses of 400 mg/kg and 800 mg/kg significantly reduced the carrageenan induced paw edema (P<0.001) at 3hr and 6hr in a dose dependent manner as compared to the vehicle control. Whereas 200mg/kg does not show any significance with that of control. As a result of the foregoing findings, the aqueous extract of Malus sylvestris fruit was found to have considerable anti-inflammatory activity in the carrageenan induced paw edema but was unable to completely prevent the inflammation.
A cluster in the making: ALMA reveals the initial conditions for high-mass cluster formation
Creators: name: Rathborne, J. M.
name: Longmore, S. N.
name: Jackson, J. M.
name: Kruijssen, J. M. D.
name: Alves, J. F.
name: Bally, J.
name: Bastian, N.
name: Contreras, Y.
name: Foster, J. B.
name: Garay, G.
name: Testi, L.
name: Walsh, A. J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: G0.253+0.016 is a molecular clump that appears to be on the verge of forming a high mass, Arches-like cluster. Here we present new ALMA observations of its small-scale (~0.07 pc) 3mm dust continuum and molecular line emission. The data reveal a complex network of emission features, the morphology of which ranges from small, compact regions to extended, filamentary structures that are seen in both emission and absorption. The dust column density is well traced by molecules with higher excitation energies and critical densities, consistent with a clump that has a denser interior. A statistical analysis supports the idea that turbulence shapes the observed gas structure within G0.253+0.016. We find a clear break in the turbulent power spectrum derived from the optically thin dust continuum emission at a spatial scale of ~0.1 pc, which may correspond to the spatial scale at which gravity has overcome the thermal pressure. We suggest that G0.253+0.016 is on the verge of forming a cluster from hierarchical, filamentary structures that arise from a highly turbulent medium. Although the stellar distribution within Arches-like clusters is compact, centrally condensed and smooth, the observed gas distribution within G0.253+0.016 is extended, with no high-mass central concentration, and has a complex, hierarchical structure. If this clump gives rise to a high-mass cluster and its stars are formed from this initially hierarchical gas structure, then the resulting cluster must evolve into a centrally condensed structure via a dynamical process.
description: 76 pages, 46 figures. Accepted ApJ
Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis
Creators: name: Wang, Jinzhao
name: Hogan, Susan L.
name: Hu, Yichun
name: Smith, Philip C.
name: La, Mary
name: Boyette, Tammy
name: Dooley, Mary Anne
name: Stewart, Paul W.
name: Falk, Ronald J.
name: Joy, Melanie S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The role of pharmacogenomics, clinical and demographic parameters in pharmacokinetic predictions was evaluated in patients receiving mycophenolic acid (MPA).
Η συνοδική διοίκηση της Εκκλησίας της Ελλάδος
Creators: name: Μπαμπατζιάνης, Ιωάννης Θεοδώρου
Publisher: name: Aristotle University of Thessaloniki
Year: 2023
Subjects: Σύνοδος
Εκκλησία της Ελλάδος
Το αυτοδιοίκητο της Εκκλησίας της Ελλάδος
Synod
The Church of Greece
The self-government of the Church of Greece

description: Η παρούσα μεταπτυχιακή διπλωματική εργασία πραγματεύεται τα βασικά και ουσιώδη ζητήματα γύρω από την συνοδική διοίκηση της Εκκλησίας της Ελλάδος, τόσο από την Ιερά Σύνοδο της Ιεραρχίας, όσο και από την Διαρκή Ιερά Σύνοδο. Εξετάστηκε ενδελεχώς το συνοδικό σύστημα ως το θεμέλιο λειτουργίας της Εκκλησίας, καθώς και ο ρόλος και η λειτουργία της Ιεράς Συνόδου της Ιεραρχίας, όσο και της Διαρκούς Ιεράς Συνόδου. Έπειτα έγινε εκτενής αναφορά στην Αυτοκεφαλία της Εκκλησίας της Ελλάδος, μέσα από τον ρόλο που διαδραμάτισε και από την συνταγματική της κατοχύρωση. Αξίζει να σημειωθεί η σπουδαιότητα των δυο Πατριαρχικών και Συνοδικών κειμένων, του Τόμου της 29ης Ιουνίου του 1850 και της Πράξης της 4ης Σεπτεμβρίου του 1928, στην ιστορία και στην λειτουργία της Εκκλησίας της Ελλάδος. Τέλος, αναλύθηκε ο Καταστατικός της Χάρτης της Εκκλησίας της Ελλάδος ως ένα κείμενο που ορίζει τον τρόπο διοίκησης της Εκκλησίας. Επίσης το αυτοδιοίκητο της Εκκλησίας της Ελλάδος, σε σχέση με τα άρθρα 3 §1 και 13 του Συντάγματος που έχουν να κάνουν με θέματα θρησκείας, όπως και η σχέση του αυτοδιοίκητου με τα άρθρα 9 και 11 της Ευρωπαϊκής Σύμβασης Δικαιωμάτων του Ανθρώπου.
description: This postgraduate thesis deals with the basic and essential issues surrounding the synodal administration of the Church of Greece, both by the Holy Synod of the Hierarchy and by the Permanent Holy Synod. The synodal system as the foundation of the Church's operation was thoroughly examined, as well as the role and function of the Holy Synod of the Hierarchy, as well as the Permanent Holy Synod. Then an extensive reference was made to the Autocephaly of the Church of Greece, through the role it played and its constitutional enshrining. It is worth noting the importance of the two Patriarchal and Synodical texts, the Volume of June 29, 1850 and the Act of September 4, 1928, in the history and functioning of the Church of Greece. Finally, the Statutory Charter of the Church of Greece was analyzed as a text that defines the way of administration of the Church. Also the self-government of the Church of Greece, in relation to articles 3 §1 and 13 of the Constitution that have to do with matters of religion, as well as the relationship of the self-government with articles 9 and 11 of the European Convention on Human Rights.
Collaboration-Aware Graph Convolutional Network for Recommender Systems
Creators: name: Wang, Yu
name: Zhao, Yuying
name: Zhang, Yi
name: Derr, Tyler
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Retrieval (cs.IR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Graph Neural Networks (GNNs) have been successfully adopted in recommender systems by virtue of the message-passing that implicitly captures collaborative effect. Nevertheless, most of the existing message-passing mechanisms for recommendation are directly inherited from GNNs without scrutinizing whether the captured collaborative effect would benefit the prediction of user preferences. In this paper, we first analyze how message-passing captures the collaborative effect and propose a recommendation-oriented topological metric, Common Interacted Ratio (CIR), which measures the level of interaction between a specific neighbor of a node with the rest of its neighbors. After demonstrating the benefits of leveraging collaborations from neighbors with higher CIR, we propose a recommendation-tailored GNN, Collaboration-Aware Graph Convolutional Network (CAGCN), that goes beyond 1-Weisfeiler-Lehman(1-WL) test in distinguishing non-bipartite-subgraph-isomorphic graphs. Experiments on six benchmark datasets show that the best CAGCN variant outperforms the most representative GNN-based recommendation model, LightGCN, by nearly 10% in Recall@20 and also achieves around 80% speedup. Our code is publicly available at https://github.com/YuWVandy/CAGCN.
Quantization and injective submodules of differential operator modules
Creators: name: Conley, Charles H.
name: Grantcharov, Dimitar
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 17B10, 17B66

description: The Lie algebra of vector fields on $R^m$ acts naturally on the spaces of differential operators between tensor field modules. Its projective subalgebra is isomorphic to $sl_{m+1}$, and its affine subalgebra is a maximal parabolic subalgebra of the projective subalgebra with Levi factor $gl_m$. We prove two results. First, we realize all injective objects of the parabolic category O$^{gl_m}(sl_{m+1})$ of $gl_m$-finite $sl_{m+1}$-modules as submodules of differential operator modules. Second, we study projective quantizations of differential operator modules, i.e., $sl_{m+1}$-invariant splittings of their order filtrations. In the case of modules of differential operators from a tensor density module to an arbitrary tensor field module, we determine when there exists a unique projective quantization, when there exists no projective quantization, and when there exist multiple projective quantizations.
description: 30 pages, presentation reorganized
Adoção do software DSpace 7 no RCAAP
Creators: name: Carvalho, José
name: Truta, Raquel
name: Graça, Paulo
name: Lopes, Paulo
name: Ribeiro, Fernando
Publisher: name: Zenodo
Year: 2022

description: Apresentação realizada na sessão O meu Póster em 40 segundos da 13ª Conferência Lusófona de Ciência Aberta, formato híbrido, de 10 a 12 de outubro de 2022.
Variability in drug metabolizing enzyme activity in HIV-infected patients
Creators: name: Jones, Amanda E.
name: Blake, Mike
name: Werner, Rebecca E.
name: Brown, Kevin C.
name: Hein, David W.
name: Gotzkowsky, Karl
name: Gaedigk, Andrea
name: Kashuba, Angela D. M.
name: van der Horst, Charles
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: To evaluate variability in cytochrome P450 (CYP) 1A2, CYP2D6, CYP3A, N-acetyltransferase 2 (NAT2), and xanthine oxidase (XO) activity in HIV-infected patients and compare this with data from uninfected, healthy volunteers.
Optimization models of natural communication
Creators: name: Ferrer-i-Cancho, Ramon
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Computation and Language (cs.CL)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: A family of information theoretic models of communication was introduced more than a decade ago to explain the origins of Zipf's law for word frequencies. The family is a based on a combination of two information theoretic principles: maximization of mutual information between forms and meanings and minimization of form entropy. The family also sheds light on the origins of three other patterns: the principle of contrast, a related vocabulary learning bias and the meaning-frequency law. Here two important components of the family, namely the information theoretic principles and the energy function that combines them linearly, are reviewed from the perspective of psycholinguistics, language learning, information theory and synergetic linguistics. The minimization of this linear function is linked to the problem of compression of standard information theory and might be tuned by self-organization.
GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults
Creators: name: Clemmons, D
name: Ho, K
name: Cianfarani, S
name: Johannsson, G
name: Erfurth, E M
name: Chihara, K
name: Kopchick, J
name: Burman, P
name: Cohen, P
name: Robison, L
name: Lee, P
name: Radovick, S
name: Backeljauw, P
name: Grimberg, A
name: Clayton, P
name: Butler, G
name: Hokken-Koelega, A
name: Boguszewski, M
name: Pollak, M
name: Christiansen, J
name: Rosenfeld, R
name: Bidlingmaier, M
name: Hoffman, A R
name: Deal, C
name: Allen, D B
name: Dunger, D
name: Haymond, M
name: Biller, B M K
name: Higham, C
name: Juul, A
name: Fuqua, J S
name: Darendeliler, F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Recombinant human GH (rhGH) has been in use for 30 years, and over that time its safety and efficacy in children and adults has been subject to considerable scrutiny. In 2001, a statement from the GH Research Society (GRS) concluded that ‘for approved indications, GH is safe’; however, the statement highlighted a number of areas for on-going surveillance of long-term safety, including cancer risk, impact on glucose homeostasis, and use of high dose pharmacological rhGH treatment. Over the intervening years, there have been a number of publications addressing the safety of rhGH with regard to mortality, cancer and cardiovascular risk, and the need for long-term surveillance of the increasing number of adults who were treated with rhGH in childhood. Against this backdrop of interest in safety, the European Society of Paediatric Endocrinology (ESPE), the GRS, and the Pediatric Endocrine Society (PES) convened a meeting to reappraise the safety of rhGH. The ouput of the meeting is a concise position statement.
Existence of quasi-ergodic measures and conditioned Lyapunov exponents for open random dynamical systems
Creators: name: Manzatto De Castro, Matheus
Publisher: name: Imperial College London
Year: 2024

description: We study the statistical properties of open random dynamical systems via absorbing Markov processes. This thesis is structured \add{into} two parts. The first \add{part} addresses the existence of quasi-ergodic measures, \add{and the second part} establishes \add{the existence of} conditioned Lyapunov exponents \add{under} suitable conditions. In Chapters \ref{chapter:SF} and \ref{chapter:F}, leveraging the Banach lattice theory, we establish the existence of quasi-stationary and quasi-ergodic measures via a functional analytic \add{approach} for a wide class of open random dynamical systems, \add{under mild} assumptions on their transition kernel and transitiv\add{ity} properties, \add{p}roposing a novel and effective approach to the existence of such measures. In Chapter \ref{Chapter:CLE}, we use the objects established in the previous chapters to prove the existence of a fully conditioned Lyapunov spectrum for open random dynamical systems. Also, we propose a method to treat smooth, conditioned dynamics effectively and robustly, providing a novel perspective on their long-term behaviour before escape.
Aspirin in the primary prevention of cardiovascular disease in the Women’s Health Study: Effect of noncompliance
Creators: name: Cole, Stephen R.
name: Cook, Nancy R.
name: Buring, Julie E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Randomized evidence for aspirin in the primary prevention of cardiovascular disease (CVD) among women is limited and suggests at most a modest effect for total CVD. Lack of compliance, however, can null-bias estimated effects. We used marginal structural models (MSMs) to estimate the etiologic effect of continuous aspirin use on CVD events among 39,876 apparently healthy female health professionals aged 45 years and older in the Women’s Health Study, a randomized trial of 100 mg aspirin every other day versus placebo. As-treated analyses and MSMs controlled for time-varying determinants of aspirin use and CVD. Predictors of aspirin use differed by randomized group and prior use and included medical history, CVD risk factors, and intermediate CVD events. Previously reported intent-to-treat analyses found small non-significant effects of aspirin on total CVD (hazard ratio (HR) =0.91, 95% confidence interval (CI) =0.81–1.03) and CVD mortality (HR=0.95, 95% CI=0.74–1.22). As-treated analyses were similar for total CVD with a slight reduction in CVD mortality (HR=0.88, 95%CI=0.67–1.16). MSMs, which adjusted for non-compliance, were similar for total CVD (HR=0.93; 95% CI: 0.81, 1.07) but suggested lower CVD mortality with aspirin use (HR = 0.76; 95% CI: 0.54, 1.08). Adjusting for non-compliance had little impact on the estimated effect of aspirin on total CVD, but strengthened the effect on CVD mortality. These results support a limited effect of low-dose aspirin on total CVD in women, but potential benefit for CVD mortality.
A search for dark matter among Fermi-LAT unidentified sources with systematic features in Machine Learning
Creators: name: Gammaldi, V.
name: Zaldívar, B.
name: Sánchez-Conde, M. A.
name: Coronado-Blázquez, J.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences

description: Around one third of the point-like sources in the Fermi-LAT catalogs remain as unidentified sources (unIDs) today. Indeed, these unIDs lack a clear, univocal association with a known astrophysical source. If dark matter (DM) is composed of weakly interacting massive particles (WIMPs), there is the exciting possibility that some of these unIDs may actually be DM sources, emitting gamma rays from WIMPs annihilation. We propose a new approach to solve the standard, Machine Learning (ML) binary classification problem of disentangling prospective DM sources (simulated data) from astrophysical sources (observed data) among the unIDs of the 4FGL Fermi-LAT catalogue. We artificially build two {\it systematic} features for the DM data which are originally inherent to observed data: the detection significance and the uncertainty on the spectral curvature. We do it by sampling from the observed population of unIDs, assuming that the DM distributions would, if any, follow the latter. We consider different ML models: Logistic Regression, Neural Network (NN), Naive Bayes and Gaussian Process, out of which the best, in terms of classification accuracy, is the NN, achieving around $93.3\% \pm 0.7\%$ performance. Other ML evaluation parameters, such as the True Negative and True Positive rates, are discussed in our work. Applying the NN to the unIDs sample, we find that the degeneracy between some astrophysical and DM sources can be partially solved within this methodology. Nonetheless, we conclude that there are no DM source candidates among the pool of 4FGL Fermi-LAT unIDs.
description: 14 pages, 18 figures, accepted by MNRAS
กลวิธีทางภาษาเพื่อการจัดการสัมพันธภาพของพนักงานสายการบินต้นทุนต่ำในการปฏิเสธการขอร้องต่อผู้โดยสาร
Creators: name: ศิรวัตร ไทยแท้
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2018
Subjects: การจัดการสัมพันธภาพ
ความสุภาพ
วจนกรรม
การปฏิเสธการขอร้อง
สายการบินต้นทุนต่ำ

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 18, 1, 119-151
Quantifying the contributions of behavioral and biological risk factors to socioeconomic disparities in coronary heart disease incidence: the MORGEN study
Creators: name: Monique Verschuren, W. M.
name: Robinson, Whitney R.
name: Daviglus, Martha L.
name: Kershaw, Kiarri N.
name: Carnethon, Mercedes R.
name: Droomers, Mariël
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Quantifying the impact of different modifiable behavioral and biological risk factors on socioeconomic disparities in coronary heart disease (CHD) may help inform targeted, population-specific strategies to reduce the unequal distribution of the disease. Previous studies have used analytic approaches that limit our ability to disentangle the relative contributions of these risk factors to CHD disparities. The goal of this study was to assess mediation of the effect of low education on incident CHD by multiple risk factors simultaneously. Analyses are based on 15,067 participants of the Dutch Monitoring Project on Risk Factors for Chronic Diseases aged 20–65 years examined 1994–1997 and followed for events until January 1, 2008. Path analysis was used to quantify and test mediation of the low education-CHD association by behavioral (current cigarette smoking, heavy alcohol use, poor diet, and physical inactivity) and biological (obesity, hypertension, diabetes, and hypercholesterolemia) risk factors. Behavioral and biological risk factors accounted for 56.6% (95% CI: 42.6%–70.8%) of the low education-incident CHD association. Smoking was the strongest mediator, accounting for 27.3% (95% CI: 17.7%–37.4%) of the association, followed by obesity (10.2%; 95% CI: 4.5%–16.1%), physical inactivity (6.3%; 95% CI: 2.7%–10.0%), and hypertension (5.3%; 95% CI: 2.8%–8.0%). In summary, in a Dutch cohort, the majority of the relationship between low education and incident CHD was mediated by traditional behavioral and biological risk factors. Addressing barriers to smoking cessation, blood pressure and weight management, and physical activity may be the most effective approaches to eliminating socioeconomic inequalities in CHD.
มรณกรรมของหลินเปียวเมื่อ ค.ศ. 1971: จุดจบของผู้นำ ที่ทะเยอทะยานหรือเหยื่อของการปฏิวัติวัฒนธรรม?
Creators: name: สิทธิพล เครือรัฐติกาล
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2018
Subjects: หลินเปียว
เหมาเจ๋อตง
การปฏิวัติวัฒนธรรม

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 18, 1, 152-171
Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium
Creators: name: Brennan, Paul
name: Purdue, Mark P.
name: Stucker, Isabelle
name: Castellsague, Xavier
name: Leoncini, Emanuele
name: Zhang, Zuo-Feng
name: Olshan, Andrew F.
name: Levi, Fabio
name: Arzani, Dario
name: Kelsey, Karl
name: Shangina, Oxana
name: Petrelli, Livia
name: Dal Maso, Luigino
name: Ricciardi, Walter
name: Schwartz, Stephen M.
name: Franceschi, Silvia
name: Herrero, Rolando
name: Lazarus, Philip
name: Luce, Daniele
name: Winn, Deborah M.
name: Koifman, Sergio
name: Hayes, Richard B.
name: Vaughan, Thomas L.
name: La Vecchia, Carlo
name: Cadoni, Gabriella
name: McClean, Michael
name: Paludetti, Gaetano
name: Muscat, Joshua
name: Talamini, Renato
name: Matsuo, Keitaro
name: Morgenstern, Hal
name: Chen, Chu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Several epidemiological studies have shown a positive association between adult height and cancer incidence. The only study conducted among women on mouth and pharynx cancer risk, however, reported an inverse association. This study aims to investigate the association between height and the risk of head and neck cancer (HNC) within a large international consortium of HNC.
Strong coupling expansion in $\mathbf{\mathcal N=2}$ superconformal theories and the Bessel kernel
Creators: name: Beccaria, M.
name: Korchemsky, G. P.
name: Tseytlin, A. A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider strong 't Hooft coupling expansion in special four-dimensional $\mathcal N=2$ superconformal models that are planar-equivalent to $\mathcal N=4$ super Yang-Mills theory. Various observables in these models that admit localization matrix model representation can be expressed at large $N$ in terms of a Fredholm determinant of a Bessel operator. The latter previously appeared in the study of level spacing distributions in matrix models and, more recently, in four-point correlation functions of infinitely heavy half-BPS operators in planar $\mathcal N=4$ SYM. We use this relation and a suitably generalized Szego-Akhiezer-Kac formula to derive the strong 't Hooft coupling expansion of the leading corrections to free energy, half-BPS circular Wilson loop, and certain correlators of chiral primaries operators in the $\mathcal N=2$ models. This substantially generalizes partial results in the literature and represents a challenge for dual string theory calculations in AdS/CFT context. We also demonstrate that the resulting strong-coupling expansions suffer from Borel singularities and require adding non-perturbative, exponentially suppressed corrections. As a byproduct of our analysis, we determine the non-perturbative correction to the above mentioned four-point correlator in planar $\mathcal N=4$ SYM.
description: 65 pages. v2: misprints and eq.(4.20) corrected, note added; v3: minor clarifications