cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Tris-chelated complexes of nickel(II) with bipyridine derivatives: DNA binding and cleavage, BSA binding, molecular docking, and cytotoxicity
Creators: name: Anjomshoa, Marzieh
name: Torkzadeh-Mahani, Masoud
name: Sahihi, Mehdi
name: Rizzoli, Corrado
name: Ansari, Mehdi
name: Janczak, Jan
name: Esfahani, Sheila Sherafat
name: Farangis Ataei
name: Monireh Dehkhodaei
name: Bagher Amirheidari
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Two nickel(II) complexes with substituted bipyridine ligand of the type [Ni(NN)3](ClO4)2, where NN is 4,4′-dimethyl-2,2′-bipyridine (dimethylbpy) (1) and 4,4′-dimethoxy-2,2′-bipyridine (dimethoxybpy) (2), have been synthesized, characterized, and their interaction with DNA and bovine serum albumin (BSA) studied by different physical methods. X-ray crystal structure of 1 shows a six-coordinate complex in a distorted octahedral geometry. DNA-binding studies of 1 and 2 reveal that both complexes sit in DNA groove and then interact with neighboring nucleotides differently; 2 undergoes a partial intercalation. This is supported by molecular-docking studies, where hydrophobic interactions are apparent between 1 and DNA as compared to hydrogen bonding, hydrophobic, and π–π interactions between 2 and DNA minor groove. Moreover, the two complexes exhibit oxidative cleavage of supercoiled plasmid DNA in the presence of hydrogen peroxide as an activator in the order of 1 > 2. In terms of interaction with BSA, the results of spectroscopic methods and molecular docking show that 1 binds with BSA only via hydrophobic contacts while 2 interacts through hydrophobic and hydrogen bonding. It has been extensively demonstrated that the nature of the methyl- and methoxy-groups in ligands is a strong determinant of the bioactivity of nickel(II) complexes. This may justify the above differences in biomolecular interactions. In addition, the in vitro cytotoxicity of the complexes on human carcinoma cells lines (MCF-7, HT-29, and U-87) has been examined by MTT assay. According to our observations, 1 and 2 display cytotoxicity activity against selected cell lines. Communicated by Ramaswamy H. Sarma
title: Analysis of Experimental Wood Chipper Trauma on Bone
Creators: name: Domenick, Kenneth
Publisher: name: George Mason University
Year: 2012
Subjects: subject: Wood Chipper
subject: Anthropology
subject: FOS: Sociology
subject: Bone
subject: Trauma
subject: Forensic
subject: Dismemberment

description: In the literature and research relating to human corpse dismemberment and mutilation, there are few studies focusing on wood chipper induced trauma. Most of what is known about wood chipper trauma is based on a handful of documented cases in which wood chippers were used for dismemberment. In pop culture media such as movies, television, and the internet, body disposal via wood chipper is portrayed as a quick and effective method of getting rid of a body and eliminating evidence while avoiding detection. This thesis addresses these shortcomings by providing thorough case reviews and a preliminary study on wood chipper induced trauma. Several case studies are analyzed in which wood chippers were used in criminal cases to dispose of bodies. From these we learn that when wood chippers are used to dispose of human remains and that small potentially difficult to recover bone fragments are produced. Furthermore, a laboratory experiment was designed to test the trauma produced when domestic pig (Sus scrofa) limbs were inserted into a home model wood chipper. Results show that bone fragment sizes range from 45 mm to less than 1 mm. Many of the larger fragments have one or two cuts with those cuts creating fragments with consistent diameters. This wood chipper also produced bone alterations including square, V-shaped, and W-shaped kerfs that were dissimilar to other types of sharp force trauma. Some of these defects may be class characteristics associated with this model of wood chipper while others may be individual characteristics due to wear-related defects of the specific wood chipper used. This thesis will assist the forensic community by providing information regarding trauma that can expected to be observed following dismemberment via wood chipper thereby facilitating event reconstruction, victim identification, and conviction of perpetrators.
Pionic decay of a possible d'-dibaryon and the short-range NN interaction
Creators: name: Obukhovsky, I. T.
name: Itonaga, K.
name: Wagner, Georg
name: Buchmann, A. J.
name: Faessler, Amand
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the pionic decay of a possible dibaryon d' --> N N πin the microscopic quark shell model. The initial d' dibaryon wave function (J^P=0^-, T=0) consists of one 1\hbarωsix-quark shell-model s^5p[51]_X configuration. The most important final six-quark configurations s^6[6]_X, s^4p^2[42]_X and (s^4p^2-s^52s)[6]_X are properly projected onto the NN channel. The final state NN interaction is investigated by means of two phase-equivalent - but off-shell different - potential models. We demonstrate that the decay width Γ_d' depends strongly on the short-range behavior of the NN wave function. In addition, the width Γ_d' is very sensitive to the mass and size of the d' dibaryon. For dibaryon masses slightly above the experimentally suggested value M_d'=2.065 GeV, we obtain a pionic decay width of Γ_d' = 0.18 - 0.32 MeV close to the experimental value Γ_d' = 0.5 MeV.
description: 28 pages, Revtex, three ps-figures included, accepted for publication in Phys.Rev.C (1997)
WIMPs and stellar-mass primordial black holes are incompatible
Creators: name: Adamek, Julian
name: Byrnes, Christian T.
name: Gosenca, Mateja
name: Hotchkiss, Shaun
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We recently showed that postulated ultracompact minihalos with a steep density profile do not form in realistic simulations with enhanced initial perturbations. In this paper we assume that a small fraction of the dark matter consists of primordial black holes (PBHs) and simulate the formation of structures around them. We find that in this scenario halos with steep density profiles do form, consistent with theoretical predictions. If the rest of the dark matter consists of weakly interacting massive particles (WIMPs), we also show that WIMPs in the dense innermost part of these halos would annihilate and produce a detectable gamma-ray signal. The non-detection of this signal implies that PBHs make up at most one billionth of the dark matter, provided that their mass is greater than one millionth of the mass of the Sun. Similarly, a detection of PBHs would imply that the remaining dark matter could not be WIMPs.
description: 10 pages, 8 figures. v2: Minor changes to match the published version
Megascolecidae
Creators: name: Dudas, Rafaela T.
name: Demetrio, Wilian C.
name: Maia, Liliane S.
name: Sátiro, José N. O.
name: Silva, Karlo A.
name: Nicola, Vitoria B.
name: Kille, Peter
name: Oliveira, Cintía M. R.
name: Afonso, Rita O.
name: Russell, Georgina
name: Ferreira, Nuno G. C.
name: Cunha, Luis
name: Brown, George G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Opisthopora
Megascolecidae

description: Megascolecidae (juveniles)   BRPR1220, 1 individual with DNA analysis (GAN: OQ077063), BRPR1954, 1 individual with DNA analysis (GAN: OQ077065), in annual crop under No-Tillage System in Palmeira – PR, - 25.38990°S, - 49.97696°W, 897 msnm, June 2018 R. T. Dudas, K.A. da Silva, W.C. Demetrio, L.S. Maia, A. Pasini, C.M. R. Oliveira, G.G. Brown, M.L.C. Bartz colls.
description: Published as part of Dudas, Rafaela T., Demetrio, Wilian C., Maia, Liliane S., Sátiro, José N. O., Silva, Karlo A., Nicola, Vitoria B., Kille, Peter, Oliveira, Cintía M. R., Afonso, Rita O., Russell, Georgina, Ferreira, Nuno G. C., Cunha, Luis & Brown, George G., 2023, Earthworm communities in long-term no-tillage systems and secondary forest fragments in Paraná, Southern Brazil, pp. 347-361 in Zootaxa 5255 (1) on page 355, DOI: 10.11646/zootaxa.5255.1.28, http://zenodo.org/record/7745029
Thermodynamic Properties of Generalized Exclusion Statistics
Creators: name: Yang, Hyun Seok
name: Lee, Bum-Hoon
name: Park, Chanyong
Publisher: name: arXiv
Year: 1996
Subjects: subject: Condensed Matter (cond-mat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We analytically calculate some thermodynamic quantities of an ideal $g$-on gas obeying generalized exclusion statistics. We show that the specific heat of a $g$-on gas ($g \neq 0$) vanishes linearly in any dimension as $T \to 0$ when the particle number is conserved and exhibits an interesting dual symmetry that relates the particle-statistics at $g$ to the hole-statistics at $1/g$ at low temperatures. We derive the complete solution for the cluster coefficients $b_l(g)$ as a function of Haldane's statistical interaction $g$ in $D$ dimensions. We also find that the cluster coefficients $b_l(g)$ and the virial coefficients $a_l(g)$ are exactly mirror symmetric ($l$=odd) or antisymmetric ($l$=even) about $g=1/2$. In two dimensions, we completely determine the closed forms about the cluster and the virial coefficients of the generalized exclusion statistics, which exactly agree with the virial coefficients of an anyon gas of linear energies. We show that the $g$-on gas with zero chemical potential shows thermodynamic properties similar to the photon statistics. We discuss some physical implications of our results.
description: 24 pages, Revtex, Corrected typos
Enhancements to the GW space-time method
Creators: name: Steinbeck, L.
name: Rubio, A.
name: Reining, L.
name: Torrent, M.
name: White, I. D.
name: Godby, R. W.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We describe the following new features which significantly enhance the power of the recently developed real-space imaginary-time GW scheme (Rieger et al., Comp. Phys. Commun. 117, 211 (1999)) for the calculation of self-energies and related quantities of solids: (i) to fit the smoothly decaying time/energy tails of the dynamically screened Coulomb interaction and other quantities to model functions, treating only the remaining time/energy region close to zero numerically and performing the Fourier transformation from time to energy and vice versa by a combination of analytic integration of the tails and Gauss-Legendre quadrature of the remaining part and (ii) to accelerate the convergence of the band sum in the calculation of the Green's function by replacing higher unoccupied eigenstates by free electron states (plane waves). These improvements make the calculation of larger systems (surfaces, clusters, defects etc.) accessible.
description: 10 pages, 6 figures
title: Development for Housing Analytics-HomeRun
Creators: name: Deshpande, Saurabh
Publisher: name: George Mason University
Year: 2020
Subjects: subject: Android
subject: Real estate
subject: Google Maps
subject: Heat maps
subject: Listviews

description: Real estate is a huge domain, and people think of selling, renting and purchasing the property which includes huge investments. The most important part comes while dealing with the property is “Searching”. There are millions of homes spread across US states and more and more people are hunting for properties, which suit their needs and pockets. Searching for a property has become easier because of the Internet Revolution. People have started listing the properties online. Now, as smartphones have gained huge popularity as they are handy and has access to the Internet on the go. There is an incredible growth in the operating systems that support mobile devices. Android OS and IOS are the leading operating systems that have millions of applications for their users. More than 75% of the mobile devices support Android. [1] Although these smartphones can be used to browse the web for searching the property, again one has to go do the tedious job of searching the property. Even if, one finds an interesting property listed they have to go to multiple websites to get all the information about that property and there is much more you do while considering your next home. Example, Google Maps for the location and navigation, different state websites listing corresponding state properties, list down all the details of the properties, locality inspection. To ease this process, an Android application ‘HomeRun’ which is a one-stop destination that provides users with all the necessary features integrated. One can search a property based on the location, which may include for a specific state, city or zip code. Users can also use detailed search option where they can feed in the desired number of bedrooms, price, area etc. and get a list of matching properties. Users can compare two or more properties using the feature of spider graph and also look for zones with residential areas with heat maps. Apart from all these features, the user has been provided with the ability to get directions to that property. [1] The application is developed in native Android development environment using JAVA.
Entinostat induces antitumor immune responses through immune editing of tumor neoantigens
Creators: name: Manocha, U
name: Krishnan, B
name: Utsumi, T
name: Rose, T.L
name: Perou, C.M
name: Milowsky, M.I
name: Smith, C.C
name: He, X
name: Vincent, B.G.
name: Bixby, L.M
name: Bailey, S.T.
name: Truong, A.S
name: Kim, W.Y
name: Wobker, S.E
name: Zhou, M
name: Stewart, K.G
name: Beck, W
Publisher: name: American Society for Clinical Investigation
Year: 2021

description: Although immune-checkpoint inhibitors (ICIs) have been a remarkable advancement in bladder cancer treatment, the response rate to single-agent ICIs remains suboptimal. There has been substantial interest in the use of epigenetic agents to enhance ICI efficacy, although precisely how these agents potentiate ICI response has not been fully elucidated. We identified entinostat, a selective HDAC1/3 inhibitor, as a potent antitumor agent in our immune-competent bladder cancer mouse models (BBN963 and BBN966). We demonstrate that entinostat selectively promoted immune editing of tumor neoantigens, effectively remodeling the tumor immune microenvironment, resulting in a robust antitumor response that was cell autonomous, dependent upon antigen presentation, and associated with increased numbers of neoantigen-specific T cells. Finally, combination treatment with anti–PD-1 and entinostat led to complete responses and conferred long-term immunologic memory. Our work defines a tumor cell–autonomous mechanism of action for entinostat and a strong preclinical rationale for the combined use of entinostat and PD-1 blockade in bladder cancer.
Comment on "The N = 3 Weyl Multiplet in Four Dimensions"
Creators: name: Hegde, Subramanya
name: Sahoo, Bindusar
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: N = 3 Weyl multiplet in four dimensions was first constructed in J van Muiden et al (2017) where the authors used the current multiplet approach to obtain the linearized transformation rules and completed the nonlinear variations using the superconformal algebra. The multiplet of currents was obtained by a truncation of the multiplet of currents for the N = 4 vector multiplet. While the procedure seems to be correct, the result suffers from several inconsistencies. The inconsistencies are observed in the transformation rules as well as the field dependent structure constants in the corresponding soft algebra. We take a different approach, and compute the transformation rule as well as the corresponding soft algebra by demanding consistency.
description: 7 pages, text revisions
Additional file 1 of ReUseData: an R/Bioconductor tool for reusable and reproducible genomic data management
Creators: name: Liu, Qian
name: Hu, Qiang
name: Liu, Song
name: Hutson, Alan
name: Morgan, Martin
Publisher: name: figshare
Year: 2024
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: Additional file 1. ReUseData package resources and practical use.
Additional file 1: of Incubation period of typhoidal salmonellosis: a systematic review and meta-analysis of outbreaks and experimental studies occurring over the last century
Creators: name: Awofisayo-Okuyelu, Adedoyin
name: McCarthy, Noel
name: Mgbakor, Ifunanya
name: Hall, Ian
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: List of studies excluded from the review. Table listing the studies excluded from the review. (DOCX 24 kb)
title: The cold shock Y-box protein-1 (YB-1) promotes survival of T cells and is deregulated in Systemic Lupus Erythematosus (SLE)
Creators: name: Meltendorf, Stefan
name: Fu, Hang
name: Pierau, Mandy
name: Gieseler-Halbach, Steffi
name: Handschuh, Juliane
name: Lindquist, Jonathon
name: Mertens, Peter
name: Ambach, Andreas
name: Thomas, Ulrich
name: Lingel, Holger
name: Finzel, Stephanie
name: Voll, Reinhard
name: Brunner-Weinzierl, Monika
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: The cold-shock protein YB-1 plays a central role in cell homeostasis. Here, we analyzed the relation of YB-1 to apoptosis in primarily activated T cells from healthy donors and patients suffering from Systemic Lupus Erythematosus (SLE). We could show that YB-1 expression is hardly upregulated[for full text, please go to the a.m. URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Realization spaces of 4-polytopes are universal
Creators: name: Richter-Gebert, Jürgen
name: Ziegler, Günter M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Metric Geometry (math.MG)
subject: FOS: Mathematics

description: Let $P\subset\R^d$ be a $d$-dimensional polytope. The {\em realization space} of~$P$ is the space of all polytopes $P'\subset\R^d$ that are combinatorially equivalent to~$P$, modulo affine transformations. We report on work by the first author, which shows that realization spaces of \mbox{4-dimensional} polytopes can be ``arbitrarily bad'': namely, for every primary semialgebraic set~$V$ defined over~$\Z$, there is a $4$-polytope $P(V)$ whose realization space is ``stably equivalent'' to~$V$. This implies that the realization space of a $4$-polytope can have the homotopy type of an arbitrary finite simplicial complex, and that all algebraic numbers are needed to realize all $4$- polytopes. The proof is constructive. These results sharply contrast the $3$-dimensional case, where realization spaces are contractible and all polytopes are realizable with integral coordinates (Steinitz's Theorem). No similar universality result was previously known in any fixed dimension.
description: 10 pages
Coarsened Lattice Spatial Disorder in the Thermodynamic Limit
Creators: name: Piasecki, R.
name: Czainski, A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: In this Rapid Research Note the application of recently introduced [Physica A 277 (2000) 157] entropic measure S_Delta of spatial disorder for systems of finite-sized objects is presented. In the thermodynamic limit the critical behaviour of coarsened lattice model of random two-phase systems is illustrated for certain grain size distributions (GSDs) and chosen parameters. Also the changes of spatial disorder, quantified by S_Delta, between the limit GSDs clearly show that the topological equivalence of the two phases is broken.
description: 3 pages, 1 figure
Environmental pollution is associated with increased risk of psychiatric disorders in the US and Denmark
Creators: name: Brandt J
name: Rzhetsky A
name: Antonsen S
name: Geels C
name: Sullivan P.F
name: Khan A
name: Landecker H
name: Pedersen C.B
name: Plana-Ripoll O
Publisher: name: Public Library of Science
Year: 2019

description: The search for the genetic factors underlying complex neuropsychiatric disorders has proceeded apace in the past decade. Despite some advances in identifying genetic variants associated with psychiatric disorders, most variants have small individual contributions to risk. By contrast, disease risk increase appears to be less subtle for disease-predisposing environmental insults. In this study, we sought to identify associations between environmental pollution and risk of neuropsychiatric disorders. We present exploratory analyses of 2 independent, very large datasets: 151 million unique individuals, represented in a United States insurance claims dataset, and 1.4 million unique individuals documented in Danish national treatment registers. Environmental Protection Agency (EPA) county-level environmental quality indices (EQIs) in the US and individual-level exposure to air pollution in Denmark were used to assess the association between pollution exposure and the risk of neuropsychiatric disorders. These results show that air pollution is significantly associated with increased risk of psychiatric disorders. We hypothesize that pollutants affect the human brain via neuroinflammatory pathways that have also been shown to cause depression-like phenotypes in animal studies.
title: The "Fast and Frugal" Cognitive Architecture for Computational Social Simulations
Creators: name: Kennedy, William G.
name: Bassett, Jeffrey K.
Publisher: name: Behavior Representation in Modeling & Simulation (BRIMS) Conference 2011
Year: 2011
Subjects: subject: Cognitive Architecture
subject: Agent-Based Modeling

description: Two page abstract for poster presentation.
description: Computational social simulations involving humans require models of human behavior but their behavior can be represented and modeled in many ways. The two dimensions of this challenge we are interested in are the degree of cognitive plausibility in the representation of the behavior of humans and the computational intensity involved.
Particle-Flux Separation of Electrons in the Half-Filled Landau Level: Chargeon-Fluxon Approach
Creators: name: Ichinose, I.
name: Matsui, T.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Condensed Matter (cond-mat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Mechanism of the particle-flux separation in the Chern-Simons gauge theory coupled with nonrelativistic fermions is studied in a nonperturbative method. This problem is very important for the composite fermion approach to the fractional quantum Hall effect. We show that due to repulsive interactions between electrons the composite fermions are stable quasiexcitations in the half-filled Landau level at low temperature.
description: Latex, 34 pages
Epigenome editing of the CFTR-locus for treatment of cystic fibrosis
Creators: name: Shah, N.N
name: Reddy, T.E
name: Kabadi, A.M
name: Drowley, L
name: Dalal, N
name: McDowell, I
name: Machlin, L
name: Randell, S.H
name: Lee, R.E
Publisher: name: Elsevier B.V.
Year: 2022

description: Background: Mechanisms governing the diversity of CFTR gene expression throughout the body are complex. Multiple intronic and distal regulatory elements are responsible for regulating differential CFTR expression across tissues. Methods: Drawing on published data, 18 high-priority genomic regions were identified and interrogated for CFTR-enhancer function using CRISPR/dCas9-based epigenome editing tools. Each region was evaluated by dCas9p300 and dCas9KRAB for its ability to enhance or repress CFTR expression, respectively. Results: Multiple genomic regions were tested for enhancer activity using CRISPR/dCas9 epigenome editing. dCas9p300 mediates a significant increase in CFTR mRNA levels when targeted to the promoter and a region 44 kb upstream of the transcriptional start site in a CFTR-low expressing cell line. Multiple gRNAs targeting the promoter induced a robust increase in CFTR protein levels. In contrast, dCas9KRAB-mediated repression is much more robust with 10 of the 18 evaluated genomic regions inducing CFTR protein knockdown. To evaluate the therapeutic efficacy of modulating CFTR gene regulation, dCas9p300 was used to induce elevated levels of CFTR from the endogenous locus in ΔF508/ΔF508 human bronchial epithelial cells. Ussing chamber studies demonstrated a synergistic increase in ion transport in response to CRISPR-induced expression of ΔF508 CFTR mRNA along with VX809 treatment. Conclusions: CRISPR/dCas9-based epigenome-editing provides a previously unexplored tool for interrogating CFTR enhancer function. Here, we demonstrate that therapeutic interventions that increase the expression of CFTR may improve the efficacy of CFTR modulators. A better understanding CFTR regulatory mechanisms could uncover novel therapeutic interventions for the development of cystic fibrosis therapies.
title: Cellular biomarkers in SLE to monitor immune cell- and cell signalling-dynamics
Creators: name: Baumgart, Sabine
name: Bertolo, Martina
name: Urbicht, Marie
name: Burns, Tyler
name: Biesen, Robert
name: Rose, Thomas
name: Enghard, Philipp
name: Schulz, Axel
name: Mei, Henrik
name: Grützkau, Andreas
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Cellular biomarkers are coming in focus to monitor disease activity, guide personalized treatment decisions and replace kidney biopsies in systemic lupus erythematosus (SLE). Hitherto, humoral biomarkers, such as autoantibodies, complement consumptions or creatinine are still the gold standard[for full text, please go to the a.m. URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Equitability of Individual and Population Interventions to Reduce Obesity: A Modeling Study in Mexico
Creators: name: Colchero M.A
name: Braverman-Bronstein A
name: Vidaña-Pérez D
name: Barrientos-Gutierrez T
name: Popkin B.M
name: Rivera-Dommarco J.A
name: Zepeda-Tello R
name: Camacho-García-Formentí D
Publisher: name: Elsevier Inc.
Year: 2022

description: Introduction: Modeling studies have estimated the potential impact and cost effectiveness of interventions to reduce obesity; few have focused on their equity across socioeconomic groups. This study aims to compare the equitability of individual- and population-level interventions to reduce obesity in Mexico. Methods: Mathematical models were implemented to estimate the expected effect of 2 sugar-sweetened beverage tax scenarios (10% and 20%) and bariatric surgery, pharmacotherapy, and dietary advice as individual interventions to reduce body weight. Individual interventions were modeled using meta-analytical weight change, inclusion and exclusion criteria, and the probability of access to healthcare services. For the tax, investigators obtained the baseline consumption of sugar-sweetened beverages from the National Health Survey 2012 and applied the reduction in sales observed in 2016 to estimate the caloric change and weight reduction. Implementation costs and cost per person, per kilogram, and equity were calculated for all interventions over a 1-year timeframe. Results: The 20% tax produced the largest estimated increase (4.50%) in normal BMI prevalence, was the most cost effective, and had the largest and most equitable decrease in obesity across socioeconomic categories. Pharmacotherapy and bariatric surgery produced sizable decreases in obesity prevalence (3.68% and 1.18%), particularly among the middle and high socioeconomic groups, whereas dietary advice had the lowest impact on normal and obese categories. Conclusions: Individual interventions were effective in reducing obesity; yet, they were more expensive and less equitable than population interventions. Obesity in Mexico affects all socioeconomic groups; available interventions need to be carefully analyzed to tailor a national strategy that is both effective and equitable.
Estimating the Complier Average Causal Effect in a Meta-Analysis of Randomized Clinical Trials With Binary Outcomes Accounting for Noncompliance: A Generalized Linear Latent and Mixed Model Approach
Creators: name: Zhou J
name: Zhou T
name: Chen Y
name: Cole S.R
name: Lin L
name: Chu H
name: Hodges J.S
Publisher: name: Oxford University Press
Year: 2022

description: Noncompliance, a common problem in randomized clinical trials (RCTs), can bias estimation of the effect of treatment receipt using a standard intention-to-treat analysis. The complier average causal effect (CACE) measures the effect of an intervention in the latent subpopulation that would comply with their assigned treatment. Although several methods have been developed to estimate the CACE in analyzing a single RCT, methods for estimating the CACE in a meta-analysis of RCTs with noncompliance await further development. This article reviews the assumptions needed to estimate the CACE in a single RCT and proposes a frequentist alternative for estimating the CACE in a meta-analysis, using a generalized linear latent and mixed model with SAS software (SAS Institute, Inc.). The method accounts for between-study heterogeneity using random effects. We implement the methods and describe an illustrative example of a meta-analysis of 10 RCTs evaluating the effect of receiving epidural analgesia in labor on cesarean delivery, where noncompliance varies dramatically between studies. Simulation studies are used to evaluate the performance of the proposed method.
Olympic Villages and walkability. Analysis and application of the urban model of the 15-minute city.
Creators: name: Sala, Valerio Della
Publisher: name: Zenodo
Year: 2023
Subjects: Olympic Villages; 15-minute city; walkability; urban space; mobility.

description: The observation of the territorial impact of the Olympic Villages on the city, the introduction of new models of organisation and financing of the Olympic event, is considered essential in the analysis of the processes of territorialisation and deterritorialisation linked to the territory and its transformation over time. The aim of the following contribution is to examine the walkability within the summer and winter Olympic villages. By analysing the Olympic villages through the parameters of walkability, it will be possible to observe a comparison in terms of size and connectivity within the Olympic districts. Therefore, in view of the introduction of the new guidelines, cities have consolidated a new model for the development of the Olympic Games, based mainly on existing structures and the temporary transformation of venues. The evolution of the Olympic village models implies a critical reflection on how neighbourhoods can be transformed or integrated within the urban model proposed by the 15-minute city. The composition of new housing units in the central areas of metropolises may foment the emergence of new forms of gentrifying segregation within host cities.
Olympic Villages and walkability. Analysis and application of the urban model of the 15-minute city.
Creators: name: Della Sala, Valerio
Publisher: name: Zenodo
Year: 2023
Subjects: Olympic Villages; 15-minute city; walkability; urban space; mobility.

description: The observation of the territorial impact of the Olympic Villages on the city, the introduction of new models of organisation and financing of the Olympic event, is considered essential in the analysis of the processes of territorialisation and deterritorialisation linked to the territory and its transformation over time. The aim of the following contribution is to examine the walkability within the summer and winter Olympic villages. By analysing the Olympic villages through the parameters of walkability, it will be possible to observe a comparison in terms of size and connectivity within the Olympic districts. Therefore, in view of the introduction of the new guidelines, cities have consolidated a new model for the development of the Olympic Games, based mainly on existing structures and the temporary transformation of venues. The evolution of the Olympic village models implies a critical reflection on how neighbourhoods can be transformed or integrated within the urban model proposed by the 15-minute city. The composition of new housing units in the central areas of metropolises may foment the emergence of new forms of gentrifying segregation within host cities.
title: Lowered anti-beta1 adrenergic receptor antibody concentrations may have prognostic significance in acute coronary syndrome
Creators: name: Ernst, Diana
name: Westerberg, Johan
name: Jablonka, Alexandra
name: Sogkas, Georgios
name: Ahrenstorf, Gerrit
name: Schmidt, Reinhold E.
name: Heidecke, Harald
name: Wallentin, Lars
name: Riemekasten, Gabriela
name: Witte, Torsten
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Coronary heart disease is a very common comorbidity in rheumatological diseases. Risk factors predisposing to ACS are well established, but no reliable prognostic biomarkers for post-event survival or risk of reinfarction exist. Physiological levels of antibodies against anti-beta1 adrenergic[for full text, please go to the a.m. URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Control of a nonholonomic robot in an environment with obstacles
Creators: name: Kozlowski, Krzysztof
name: Kowalczyk, Wojciech
name: Pazderski, Dariusz
Publisher: name: Zenodo
Year: 2019
Subjects: human-robot interaction
5G
mixed-reality
cognitive system
AI
holographic instructions

description: The industrial collaborative scenario is experiencing several changes, due to the influence of the new working paradigms introduced by the fourth technological revolution. In the proposed application, a cobot and a human agent have to collaborate to assemble the components of a thermostatic valve. The cobot is endowed with a cognitive unit, Smart Robots, equipped with artificial intelligence algorithms that enable it to recognize the latent co-worker intention and promote a proactive cooperation with the human partner, as well as adapting to his/her observed behaviour. Moreover, to facilitate the mutual understanding of the two agents and the fluency of the coop- eration, the application exploits the recent advances in terms of mixed-reality technologies, Microsoft HoloLens, to create a visual holographic communication channel with the co-worker. This mixed-reality wearable head-set is used to display in the operator field of view intuitive and easy-to-understand information in the form of holographic task-related projections through which he/she can be guided, assisted and warn during the various phases of the overall collaboration. Consistently with the paradigm of Industry 4.0, whose cornerstones are the flexibility and the strong interconnection among the industrial devices, the collaborative station has been endowed with ultra-fast 5G connectivity, so as to guarantee a highly reliable and very low latency data exchange between the devices. This collaborative task has proved its efficiency in terms of robustness to error propagation and cycle-time.
QED calculations of the $n=2$ to $n=1$ x-ray transition energies in middle-$Z$ heliumlike ions
Creators: name: Malyshev, A. V.
name: Kozhedub, Y. S.
name: Glazov, D. A.
name: Tupitsyn, I. I.
name: Shabaev, V. M.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Ab initio QED calculations of the four x-ray transitions from the $L$ to $K$ shell in heliumlike argon, titanium, iron, copper, and krypton are performed. The binding energies for all the $n=1$ and $n=2$ states are evaluated as well. The calculation approach combines the rigorous QED treatment in the first two orders of the perturbation theory constructed within the extended Furry picture with the third- and higher-order correlation effects evaluated in the Breit approximation. The obtained results are compared with the previous evaluations and available experimental data.
description: 7 pages, 2 figures, 4 tables
Glossoscolecidae
Creators: name: Bartz, Marie L. C.
name: Barreto, Julia
name: Santos, Alessandra
name: Dudas, Rafaela T.
name: Ferreira, Talita
name: Maia, Lilianne Dos Santos
name: Demetrio, Wilian C.
name: Smokanit, Manoela
name: Tavares, Alan A.
name: Schuster, Phillip A.
name: Hernani, Luis C.
name: Brown, George G.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Crassiclitellata
Glossoscolecidae

description: Glossoscolecidae (juveniles)   BRPR0953, 1 individual, surface soil under no-tillage in Rolândia — PR (23°18’58.02”S; 51°27’35.39”W), December 2016. M.L.C. Bartz, W.C. Demetrio, H.S. Nadolny, T. Ferreira, L.S. Maia, M. Smokanit, R. T. Dudas, A.A. T. Tavares, P.A. Shcuster colls. BRPR0954, 2 individuals, surface soil under riparian forest in Cambé — PR (23° 9’59.22”S; 51°14’16.67”W), December 2016. M.L.C. Bartz, W.C. Demetrio, H.S. Nadolny, T. Ferreira, L.S. Maia, M. Smokanit, R. T. Dudas, A.A. T. Tavares, P.A. ch (Schuster) colls. BRPR0955, 2 individuals, surface soil under riparian forest in Toledo — PR (24°48’58.54”S; 53°33’14.44”W), December 2016. M.L.C. Bartz, W.C. Demetrio, H.S. Nadolny, T. Ferreira, L.S. Maia, M. Smokanit, R. T. Dudas, A.A. T. Tavares, P.A. Shcuster colls. BRRS0294, 1 individual, surface soil under riparian forest in Sarandi —RS, (27°55’25.71”S 52°47’35.01”W) May 2019. M.L.C. Bartz, R. T. Dudas, J. Tomporowski, W.C. Demetrio colls.
description: Published as part of Bartz, Marie L. C., Barreto, Julia, Santos, Alessandra, Dudas, Rafaela T., Ferreira, Talita, Maia, Lilianne Dos Santos, Demetrio, Wilian C., Smokanit, Manoela, Tavares, Alan A., Schuster, Phillip A., Hernani, Luis C. & Brown, George G., 2023, Earthworm richness in no-tillage farming systems and riparian forests in Southern and Southeastern Brazil, pp. 362-376 in Zootaxa 5255 (1) on page 367, DOI: 10.11646/zootaxa.5255.1.29, http://zenodo.org/record/7745023
Multi-plexing single vial proces analytical technologies. Podium presentation at "Freeze Drying of Pharmaceutical and Biologicals", 2018 Sept 18 - 21, Garmisch-Partenkirchen, Germany
Creators: name: Smith, Geoff
name: Yowwares Jeeraruangrattana (Dmu Email)
Publisher: name: De Montfort University
Year: 2020
Subjects: subject: 111504 Pharmaceutical Sciences
subject: FOS: Clinical medicine

description: Cite as:Smith, G. (2018). Multi-plexing single vial proces analytical technologies. Podium presentation at "Freeze Drying of Pharmaceutical and Biologicals", Sept 18 - 21, Garmisch-Partenkirchen, Germany
 The presentation describes the use of a dual-electrode, through vial impedance spectroscopy (TVIS) method for the determination of drying rates and the prediction of ice interface and ice base temperatures from which the single vial heat transfer coefficient was calculated.
title: Anti-beta-adrenoceptor autoantibodies are elevated in systemic sclerosis
Creators: name: Dreyer, Tatjana Kathleen
name: Comdühr, Sara
name: Pitann, Silke
name: Kerstein, Anja
name: Marschner, Gabriele
name: Heidecke, Harald
name: Müller, Antje
name: Riemekasten, Gabriela
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: G protein-coupled receptors (GPCR) are expressed by many cells, including leukocytes. Apart from natural ligands, there are circulating anti-GPCR autoantibodies which are thought to modulate functions of GPCR. We hypothesise that GPCR expressed by immune cells interact with circulating anti-GPCR[for full text, please go to the a.m. URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Jeeraruangrattana et al. (2018) Poster presentation at "Freeze Drying of Pharmaceuticals and Biologicals", Sept 18-21, Garmisch-Partenkirchen, Germany
Creators: name: Smith, Geoff
name: Yowwares Jeeraruangrattana (Dmu Email)
Publisher: name: De Montfort University
Year: 2019
Subjects: subject: 111504 Pharmaceutical Sciences
subject: FOS: Clinical medicine

description: Poster title: Application of Impedance Based Technology to Investigate the Collapse of Freeze-dried Sugar-salt SolutionsYowwares Jeeraruangrattana, Irina Ermolina, Eugene Polygalov, Geoff Smith Pharmaceutical Technologies Group, Leicester School of Pharmacy, De Montfort University, UK
The d'-dibaryon in a colored cluster model
Creators: name: Buchmann, A. J.
name: Wagner, Georg
name: Faessler, Amand
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We calculate the mass and structure of a J^P=0^-, T=0 six-quark system using a colored diquark-tetraquark cluster wave function and a nonrelativistic quark model Hamiltonian. The calculated mass is some 350 MeV above the empirical value if the same confinement strength as in the nucleon is used. If the effective two-body confinement strength is weaker in a compound six-quark system than in a single baryon, as expected from a simple harmonic oscillator model, one obtains M_d' = 2092 MeV close to experiment.
description: 6 pages, Revtex, 2 ps-figures included, to appear in the Proceedings of the '6th Conference on the Intersections of Particle and Nuclear Physics' Big Sky, 1997
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0283
Creators: name: de la Côte d'Or, Archives départementales
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0283, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0283, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Gapless Color Superconductivity
Creators: name: Alford, M.
name: Berges, J.
name: Rajagopal, K.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present the dispersion relations for quasiparticle excitations about the color-flavor locked ground state of QCD at high baryon density. In the presence of condensates which pair light and strange quarks there need not be an energy gap in the quasiparticle spectrum. This raises the possibility of gapless color superconductivity, with a Meissner effect but no minimum excitation energy. Analysis within a toy model suggests that gapless color superconductivity may occur only as a metastable phase.
description: 4 pages, Revtex, eps figures included
Homotopy Lie groups
Creators: name: Møller, Jesper M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics

description: Homotopy Lie groups, recently invented by W.G. Dwyer and C.W. Wilkerson, represent the culmination of a long evolution. The basic philosophy behind the process was formulated almost 25 years ago by Rector in his vision of a homotopy theoretic incarnation of Lie group theory. What was then technically impossible has now become feasible thanks to modern advances such as Miller's proof of the Sullivan conjecture and Lannes's division functors. Today, with Dwyer and Wilkerson's implementation of Rector's vision, the tantalizing classification theorem seems to be within grasp. Supported by motivating examples and clarifying exercises, this guide quickly leads, without ignoring the context or the proof strategy, from classical finite loop spaces to the important definitions and striking results of this new theory.
description: 16 pages
Additional file 1 of Obstacles to access to community care in urban senior-only households: a qualitative study
Creators: name: Gong, Ni
name: Meng, Ya
name: Hu, Qin
name: Du, Qianqian
name: Wu, Xiaoyu
name: Zou, Wenjie
name: Zhu, Mengyao
name: Chen, Jiayan
name: Luo, Lan
name: Cheng, Yu
name: Zhang, Meifen
Publisher: name: figshare
Year: 2022
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1.
C*-algebras from actions of congruence monoids on rings of algebraic integers
Creators: name: Bruce, Chris
Publisher: name: arXiv
Year: 2019
Subjects: subject: Operator Algebras (math.OA)
subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: Primary 46L05, Secondary 11R04

description: Let $K$ be a number field with ring of integers $R$. Given a modulus $\mathfrak{m}$ for $K$ and a group $Γ$ of residues modulo $\mathfrak{m}$, we consider the semi-direct product $R\rtimes R_{\mathfrak{m},Γ}$ obtained by restricting the multiplicative part of the full $ax+b$-semigroup over $R$ to those algebraic integers whose residue modulo $\mathfrak{m}$ lies in $Γ$, and we study the left regular C*-algebra of this semigroup. We give two presentations of this C*-algebra and realize it as a full corner in a crossed product C*-algebra. We also establish a faithfulness criterion for representations in terms of projections associated with ideal classes in a quotient of the ray class group modulo $\mathfrak{m}$, and we explicitly describe the primitive ideals using relations only involving the range projections of the generating isometries; this leads to an explicit description of the boundary quotient. Our results generalize and strengthen those of Cuntz, Deninger, and Laca and of Echterhoff and Laca for the C*-algebra of the full $ax+b$-semigroup. We conclude by showing that our construction is functorial in the appropriate sense; in particular, we prove that the left regular C*-algebra of $R\rtimes R_{\mathfrak{m},Γ}$ embeds canonically into the left regular C*-algebra of the full $ax+b$-semigroup. Our methods rely heavily on Li's theory of semigroup C*-algebras.
description: final version, accepted for publication in Trans. Amer. Math. Soc.; updated introduction and bibliography; 29 pages