cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(501871) Jane Belwood Holland
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Projective objects and the modified trace in factorisable finite tensor categories
Creators: name: Gainutdinov, Azat M.
name: Runkel, Ingo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Algebra (math.QA)
subject: High Energy Physics - Theory (hep-th)
subject: Category Theory (math.CT)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 18D10, 18G05, 18F30, 17B69

description: For C a factorisable and pivotal finite tensor category over an algebraically closed field of characteristic zero we show: 1) C always contains a simple projective object; 2) if C is in addition ribbon, the internal characters of projective modules span a submodule for the projective SL(2,Z)-action; 3) the action of the Grothendieck ring of C on the span of internal characters of projective objects can be diagonalised; 4) the linearised Grothendieck ring of C is semisimple iff C is semisimple. Results 1-3 remain true in positive characteristic under an extra assumption. Result 1 implies that the tensor ideal of projective objects in C carries a unique-up-to-scalars modified trace function. We express the modified trace of open Hopf links coloured by projectives in terms of S-matrix elements. Furthermore, we give a Verlinde-like formula for the decomposition of tensor products of projective objects which uses only the modular S-transformation restricted to internal characters of projective objects. We compute the modified trace in the example of symplectic fermion categories, and we illustrate how the Verlinde-like formula for projective objects can be applied there.
description: 61 pages, v2: minor changes + references updated
title: An investigation of the radiation damage experienced by the CCDs on the Gaia focal plane
Creators: name: Ahmed, Saad
Publisher: name: The Open University
Year: 2023

description: The European Space Agency’s Gaia spacecraft was launched in December 2013 with the aim of making the largest and most precise map of the Milky Way by taking measurements of over one billion astronomical objects. It has a payload of 106 charge-coupled devices (CCDs) to help achieve its objectives. During the pre-flight testing phase of the mission, the non-ionizing energy loss (NIEL) radiation damage on the detectors was identified as a major factor that would affect the science goals of the mission. From analysis of the in-flight data, the degradation of the CCDs from radiation damage, measured as the charge-transfer inefficiency (CTI), was found to be significantly less than what was predicted from the pre-flight on-ground tests. This thesis further investigates the radiation damage of the Gaia CCDs to more precisely understand the CTI behaviour; this helps to maintain credibility in the pre-flight tests and to better prepare for future space missions. Further in-flight data is analysed and a number of new insights are revealed about the data, related to differences in behaviour between device variants and the nature of radiation damage across Gaia’s focal plane. Different factors that have combined to result in the lower in-flight CTI measurements are also studied with analysis of on-ground data and the use of different simulation models to better understand the datasets. Finally, all these factors are combined together to make an assessment on the CTI differences between Gaia’s in-flight and on-ground CCDs and propose future testing to determine any additional sources of radiation.
Quaternionic Projective Bundle Theorem and Gysin Triangle in MW-Motivic Cohomology
Creators: name: Yang, Nanjun
Publisher: name: arXiv
Year: 2017
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: In this paper, we show that the motive of the quaternionic Grassmannian $HP^n$ (as defined by I. Panin and C. Walter) splits in the category of effective MW-motives (as defined by B. Calmès, F. Déglise and J. Fasel). Moreover, we extend this result to an arbitrary symplectic bundle, obtaining the so-called quaternionic projective bundle theorem. Finally, we give the Gysin triangle in MW-motivic cohomology.
description: Final version, 16 pages, substantially revised, results improved, to appear in Manuscripta Mathematica
Observing, understanding and developing learning dispositions in an early years centre.
Creators: name: Allan, Susan
Publisher: name: Cardiff Metropolitan University
Year: 2022
Subjects: Early childhood education

description: EdD This longitudinal study investigated young children's learning within an early years
 education and care environment. The qualitative research design adopted an action
 research approach. The research methodology included; parent and staff semistructured
 and structured interviews, staff questionnaires, child observations and
 interviews. A key term in the research was that of learning dispositions to describe
 children's attitudes, actions and approaches to learning
 The study paid particular attention to children's voice, to professional debate and the
 learning environment and to how these support the development of reflective
 practitioners and reflexive practice. This research aimed to link learning theory and
 child development with early years practice in a naturalistic setting. As a professional
 doctorate it linked research project design and implementation with pedagogic
 planning and practice over a three year period. The researcher played a pivotal role as
 the manager of the study setting.
 During the research an observational framework, the child learning disposition'
 observation tool (CLDOT), was developed. This was used to complete a series of
 child learning disposition observations (CLDOs). These observations identified
 children's learning dispositions and whether they adapted them to the different
 learning environments of inside or outside, adult-led or child-led activities. These
 observations then became part of the learning disposition activity (LDA) cycle. The
 LDA cycle gave staff a practical and objective process through which they could:
 think about children's learning and use this in the planning process; observe the
 children's leaming comparing planning to practice; and deepen the reflections of
 practitioners and involve children in the process. The LDA instigated improvements
 to pedagogy and provided all involved in the research with a shared vocabulary and
 understanding of learning in the early years.
 As such, the study makes a contribution to the education debate about what is the
 right start for our youngest children at this most precious time: their early years.
(501870) Mary Ann Holland
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Lifting the Cartier transform of Ogus-Vologodsky modulo $p^n$
Creators: name: Xu, Daxin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: Let $W$ be the ring of the Witt vectors of a perfect field of characteristic $p$, $\mathfrak{X}$ a smooth formal scheme over $W$, $\mathfrak{X}'$ the base change of $\mathfrak{X}$ by the Frobenius morphism of $W$, $\mathfrak{X}_{2}'$ the reduction modulo $p^{2}$ of $\mathfrak{X}'$ and $X$ the special fiber of $\mathfrak{X}$. We lift the Cartier transform of Ogus-Vologodsky defined by $\mathfrak{X}_{2}'$ modulo $p^{n}$. More precisely, we construct a functor from the category of $p^{n}$-torsion $\mathscr{O}_{\mathfrak{X}'}$-modules with integrable $p$-connection to the category of $p^{n}$-torsion $\mathscr{O}_{\mathfrak{X}}$-modules with integrable connection, each subject to suitable nilpotence conditions. Our construction is based on Oyama's reformulation of the Cartier transform of Ogus-Vologodsky in characteristic $p$. If there exists a lifting $F:\mathfrak{X}\to \mathfrak{X}'$ of the relative Frobenius morphism of $X$, our functor is compatible with a functor constructed by Shiho from $F$. As an application, we give a new interpretation of Faltings' relative Fontaine modules and of the computation of their cohomology.
description: 96 pages, final version, to appear in M\'emoires de la Soci\'et\'e Math\'ematique de France
Prescribed mean curvature equation on the unit ball in the presence of reflection or rotation symmetry
Creators: name: Ho, Pak Tung
Publisher: name: arXiv
Year: 2017
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: Using the flow method, we prove some existence results for the problem of prescribing the mean curvature on the unit ball. More precisely, we prove that there exists a conformal metric on the unit ball such that its mean curvature is $f$, when $f$ possesses certain reflection or rotation symmetry.
description: 12 pages. Now published in Proc. Roy. Soc. Edinburgh Sect. A. Some typos are corrected
Single bag high dose intravenous N-acetylcysteine associated with decreased hepatotoxicity compared to triple bag intravenous N-acetylcysteine in high-risk acetaminophen ingestions
Creators: name: Shah, Kartik R.
name: Beuhler, Michael C.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: There is controversy that the triple bag intravenous (IV) N-acetylcysteine (NAC) regimen may be underdosing the sickest patients in its current, common usage. We hypothesize that a higher dose IV NAC regimen improves some outcomes. We conducted a poison center based retrospective observational study from January 1, 2016 to December 31, 2017 comparing a single bag higher dose IV NAC regimen (150 mg/kg over 1 h, 15 mg/kg/hour) to the triple bag IV NAC regimen (150 mg/kg over 1 h, 12.5 mg/kg/hour for 4 h, 6.25 mg/kg/hour). In a high-risk population of patients with acetaminophen ingestion (defined as multiplication product ≥ 10,000 mg/L IU/L, not acute ingestions receiving NAC within 8 h, and not hepatotoxic on first contact), we evaluated the rate of hepatotoxicity, peak transaminase, and rate of laboratory coagulopathy. 89 patients met the inclusion criteria. 12 of the 23 patients (52%) who received triple bag NAC became hepatotoxic and 10 (43%) became coagulopathic, while only 19 of 66 patients (29%) who received single bag NAC became hepatotoxic and 15 (23%) became coagulopathic; p = .043 and .057, resp. Mean peak transaminase was 4481 IU/L vs 2143 IU/L in those receiving triple bag NAC vs single bag NAC, difference of means 2338 IU/L; p = .026. In this exploratory study of a high-risk population of patients with acetaminophen ingestions, the single bag IV NAC regimen was associated with lower peak transaminase and fewer patients becoming hepatotoxic as compared to the triple bag IV NAC regimen.
Wastewater analysis for psychoactive substances at music festivals across New South Wales, Australia in 2019–2020
Creators: name: Brett, Jonathan
name: Siefried, Krista J.
name: Healey, Amy
name: Harrod, Mary Ellen
name: Franklin, Erica
name: Barratt, Monica J.
name: Masters, Jem
name: Nguyen, Lynn
name: Adiraju, Santosh
name: Gerber, Cobus
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Implementation of wastewater surveillance at music festivals has been limited to date. We aimed to use wastewater analysis and a self-report survey to determine the range of psychoactive substances being used during a music festival season in New South Wales, Australia. We sampled six single-day music festivals requiring a music festival license in New South Wales from March 2019 to March 2020; between 15% and 100% of portaloos (temporary, un-fixed toilet facilities) were sampled at each festival. Samples were screened for 98 psychoactive substances and/or their metabolites with results qualitatively expressed as detection frequencies for each substance at each festival and across all festivals. We compared these data with the results of surveys of self-reported drug use at four of the six festivals. Festival attendance ranged from 6200 to 14,975 people. Amphetamine, cocaine, ketamine, methylone, MDMA, MDA, alprazolam, diazepam, etizolam, oxazepam and temazepam were found in almost all samples from all festivals. Ethylone, mephedrone and methcathinone were also found in over 50% of festivals. A norfentanyl (a fentanyl metabolite) and n-ethylpentylone were found at 2/6 and 1/6 festivals. No festival survey participant reported intentionally taking cathinones. The detection frequency for cathinones was higher than expected relative to recent other data sources and this may represent adulteration or substitution. Similarly, the appearance of etizolam may be related to the use of counterfeit alprazolam. The detection of highly toxic substances such as N-ethylpentylone and norfentanyl may warrant public health alerts. If provided close to real time, wastewater analysis at festivals could be complemented with information sources such as drug checking, on-site surveys, medical presentations and intelligence from peer networks to feed into early warning systems, public health alerts and peer-based harm reduction education during the festival season.
A Correlative Denoising Autoencoder to Model Social Influence for Top-N Recommender System
Creators: name: Pan, Yiteng
name: He, Fazhi
name: Yu, Haiping
Publisher: name: arXiv
Year: 2017
Subjects: subject: Information Retrieval (cs.IR)
subject: Machine Learning (cs.LG)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: In recent years, there are numerous works been proposed to leverage the techniques of deep learning to improve social-aware recommendation performance. In most cases, it requires a larger number of data to train a robust deep learning model, which contains a lot of parameters to fit training data. However, both data of user ratings and social networks are facing critical sparse problem, which makes it not easy to train a robust deep neural network model. Towards this problem, we propose a novel Correlative Denoising Autoencoder (CoDAE) method by taking correlations between users with multiple roles into account to learn robust representations from sparse inputs of ratings and social networks for recommendation. We develop the CoDAE model by utilizing three separated autoencoders to learn user features with roles of rater, truster and trustee, respectively. Especially, on account of that each input unit of user vectors with roles of truster and trustee is corresponding to a particular user, we propose to utilize shared parameters to learn common information of the units that corresponding to same users. Moreover, we propose a related regularization term to learn correlations between user features that learnt by the three subnetworks of CoDAE model. We further conduct a series of experiments to evaluate the proposed method on two public datasets for Top-N recommendation task. The experimental results demonstrate that the proposed model outperforms state-of-the-art algorithms on rank-sensitive metrics of MAP and NDCG.
description: Accepted by Frontiers of Computer Science
(501869) Henry Harrington Holland
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Quantity of phenibut in dietary supplements before and after FDA warnings
Creators: name: Cohen, Pieter A.
name: Ellison, Ross R.
name: Travis, John C.
name: Gaufberg, Slava V.
name: Gerona, Roy
Publisher: name: Taylor & Francis
Year: 2021
Subjects: Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Science Policy
Hematology

description: Phenibut is used to treat anxiety, insomnia, alcohol withdrawal and other conditions in Russia. The drug, however, has abuse potential and may cause lethargy, delirium, psychosis and coma. In the United States (US), the US Food and Drug Administration (FDA) has never approved the use of phenibut as a prescription medication, but the drug is available over-the-counter in dietary supplements. More than 80 cases of coma and death have been associated with phenibut consumption and withdrawal, and the FDA recently warned that the drug is not permitted in over-the-counter supplements. We designed our study to determine the presence and quantity of phenibut in over-the-counter supplements before and after the FDA warnings. Phenibut products were included if they (a) listed phenibut or a synonym as an ingredient on the label, (b) were labeled as a dietary supplement, and (c) were available for sale both before and after the FDA warning. Supplements were analyzed by liquid chromatography time-of-flight mass spectrometry; quantification was performed by isotope dilution method. Four brands of dietary supplements labeled as containing phenibut met the inclusion criteria. Prior to the FDA warnings, two of the four brands contained phenibut, at dosages of 484 mg and 487 mg per serving. After the FDA warning, all four products contained phenibut, ranging in dosages from 21 mg to 1,164 mg per serving. Phenibut was first detected only after the FDA warnings in two brands, and the quantity of phenibut increased in three of four products after the FDA warnings. Quantities detected per dose were as much as 450% greater than a typical 250 mg pharmaceutical tablet manufactured in Russia. Following FDA issuing an advisory that phenibut is not permitted in dietary supplements, the quantity of phenibut increased in 3 of 4 brands of over-the-counter phenibut supplements.
Linear syzygies, hyperbolic Coxeter groups and regularity
Creators: name: Constantinescu, Alexandru
name: Kahle, Thomas
name: Varbaro, Matteo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Commutative Algebra (math.AC)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: Primary: 13F55, 20F55, Secondary: 13D02

description: We show that the virtual cohomological dimension of a Coxeter group is essentially the regularity of the Stanley--Reisner ring of its nerve. Using this connection between geometric group theory and commutative algebra, as well as techniques from the theory of hyperbolic Coxeter groups, we study the behavior of the Castelnuovo--Mumford regularity of square-free quadratic monomial ideals. We construct examples of such ideals which exhibit arbitrarily high regularity after linear syzygies for arbitrarily many steps. We give a doubly logarithmic bound on the regularity as a function of the number of variables if these ideals are Cohen--Macaulay.
description: 22 pages, v2: final version as in Compositio Math
(501867) Charlotte Holland
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Virtual Resolutions for a Product of Projective Spaces
Creators: name: Berkesch, Christine
name: Erman, Daniel
name: Smith, Gregory G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Commutative Algebra (math.AC)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: Syzygies capture intricate geometric properties of a subvariety in projective space. However, when the ambient space is a product of projective spaces or a more general smooth projective toric variety, minimal free resolutions over the Cox ring are too long and contain many geometrically superfluous summands. In this paper, we construct some much shorter free complexes that better encode the geometry.
description: 22 pages, 1 figure
(501866) John William Holland
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Rayleigh anomalies and disorder-induced mixing of polarizations at nanoscale in amorphous solids. Testing 1-octyl-3-methylimidazolium chloride glass
Creators: name: Izzo, Maria Grazia
name: Wehinger, Bjorn
name: Cazzato, Stefano
name: Matic, Aleksandar
name: Masciovecchio, Claudio
name: Gessini, Alessandro
name: Ruocco, Giancarlo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Acoustic excitations in topologically disordered media at mesoscale present anomalous features with respect to the Debye's theory. In a three-dimensional medium an acoustic excitation is characterized by its phase velocity, intensity and polarization. The so-called Rayleigh anomalies, which manifest in attenuation and retardation of the acoustic excitations, affect the first two properties. The topological disorder is, however, expected to influence also the third one. Acoustic excitations with a well-defined polarization in the continuum limit present indeed a so-called mixing of polarizations at nanoscale, as attested by experimental observations and Molecular Dynamics simulations. We provide a comprehensive experimental characterization of acoustic dynamics properties of a selected glass, 1-octyl-3-methylimidazolium chloride glass, whose heterogeneous structure at nanoscale is well-assessed. Distinctive features, which can be related to the occurrence of the Rayleigh anomalies and of the mixing of polarizations are observed. We develop, in the framework of the Random Media Theory, an analytical model that allows a quantitative description of all the Rayleigh anomalies and the mixing of polarizations. Contrast between theoretical and experimental features for the selected glass reveals an excellent agreement. The quantitative theoretical approach permits thus to demonstrate how the mixing of polarizations generates distinctive feature in the dynamic structure factor of glasses and to unambiguously identify them. The robustness of the proposed theoretical approach is validated by its ability to describe as well transverse acoustic dynamics.
description: 14 pages, 8 figures. Revised version, comparison between experimental data and theory is improved. Fig. 3 is new
The acute paraquat poisoning mortality (APPM) score to predict the risk of death in paraquat-poisoned patients
Creators: name: Chen, Chun-Kuei
name: Chen, Yen-Chia
name: Mégarbane, Bruno
name: Yeh, Ying-Tse
name: Chaou, Chung-Hsien
name: Chang, Chia-Hsun
name: Lin, Chih-Chuan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Mortality prediction in paraquat poisoning is a major issue since most prediction rules are inapplicable if the exact ingestion time cannot be determined and/or the serum paraquat concentration is not readily available, as in most countries. Therefore, we aimed to develop and validate a new prediction rule not requiring these two parameters. We designed a 10-year observational cohort study including all consecutive paraquat-poisoned patients managed in two Taiwanese hospitals. We built one cohort to define and one cohort to validate this prediction rule. Parameters independently related to mortality determined using a multivariate analysis were used to formulate the Acute Paraquat Poisoning Mortality (APPM) score. Overall, 321 paraquat-poisoned patients were included, 156 in the derivation and 165 in the validation cohort. Mortality rates in the derivation and validation cohorts were 73% and 81%, respectively (p = 0.20). The three parameters chosen of 28-day mortality at presentation were urine paraquat level >10 ppm (using a colorimetric sodium dithionite-based test; odds ratio (OR), 12.70; 95% confidence interval (CI), 2.64–61.24), white blood cells >13.0 G/L (OR, 5.50; CI, 1.41–21.48) and blood glucose >140 mg/dL [7.8 mmol/L] (OR, 7.45; CI, 1.70–32.86). In the derivation cohort, the area under the ROC curve (AUC-ROC) of the APPM score did not significantly differ from AUC-ROCs of serum paraquat (0.95, p = 0.25) and the Severity Index of Paraquat Poisoning (0.95, p = 0.33). AUC-ROCs of the APPM score in the derivation and validation cohorts were 0.91 and 0.94, respectively. We built and validated a reliable score to predict 28-day mortality in paraquat-poisoned patients at presentation, independently from the ingestion time and serum paraquat measurement.
(501865) Mary Ann Harrington
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Exact Time-Dependent Solution to the Three-Dimensional Euler- Helmholtz and Riemann-Hopf Equations for Vortex Flow of a Compressible Medium and the Sixth Millennium Prize Problem
Creators: name: Chefranov, Sergey G.
name: Chefranov, Artem S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Physics (physics.gen-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: For the first time the exact vortex solution of the Cauchy problem in unbounded space is obtained for the three-dimensional Euler-Helmholtz (EH) equation in the case of a nonzero-divergence velocity field for an ideal compressible medium. The solution obtained describes the inertial vortex motion and coincides with the exact solution to the three-dimensional Riemann-Hopf (RH) equation which simulates turbulence without pressure [Chefranov, 1991]. A necessary and sufficient condition of the onset of a singularity in the evolution of the enstrophy in finite time t=t0 is obtained for this solution when its continuation is possible in times t>=t0 in the Sobolev space H^0(R^3) but cannot be made in H^1(R^3). A closed description of the evolution of the enstrophy and the all other moments of the velocity and vortex fields is given, i.e., the main problem of theory of turbulence is solved exactly. The possibility of continuation of the obtained smooth solution to the EH an RH equations in the Sobolev space H^q(R^3) is also demonstrated for any q>=1 and t>=t0 due to introduction of a fairly large homogeneous friction or by introducing an arbitrary small effective volume viscosity. A new analytic solution of the Cauchy problem for the three-dimensional Navier-Stokes (NS) equation is obtained. This solution coincides with the above-mentioned smooth solution to the EH and RH equations, which take into account the viscosity effect of a compressible medium and also the sufficient condition of positive definiteness of the growth rate of the entropy in the form of a linear relation between the pressure and the divergence of the velocity field. This gives the positive solution to the generalization of the Millennium Prize Problem on the compressible Navier-Stokes equation where only the modification of viscous force is used (by introduction of homogeneous friction and etc.).
(501864) John George Grey Rea
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Covariant c-flation: a variational approach
Creators: name: Costa, Renato
name: Cuzinatto, Rodrigo R.
name: Ferreira, Elisa. M. G.
name: Franzmann, Guilherme
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We develop an action principle to construct the dynamics that give rise to a minimal generalization of Einstein's equations, where the speed of light ($c$), the gravitational constant ($G$) and the cosmological constant ($Λ$) are allowed to vary. Our construction preserves general covariance of the theory, which yields a general dynamical constraint on $c$, $G$ and $Λ$. This action is general and can be applied to describe different cosmological solutions. We apply this formulation to the initial condition puzzles of the early universe and show that it generates a dynamical mechanism to obtain the homogeneous and flat universe we observe today. We rewrite the conditions necessary to solve the horizon and flatness problems in this framework, which does not necessarily lead to an accelerated expansion as in inflation. Then, we show how the dynamics of the scalar field that represents $c$ or $G$ (and $Λ$) can be used to solve the problems of the early universe cosmology by means of different ways to c-inflate the horizon in the early universe. By taking $Λ= 0$, we show that the dynamics of the scalar field representing $c$ can be described once a potential is given.
description: 19 pages
(501863) Juliana [Lambert]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Clinical presentation of type 1 and type 2 pyrethroid poisoning in humans
Creators: name: Jacob, Manna Sera
name: Iyyadurai, Ramya
name: Jose, Arun
name: Fleming, Jude Joseph
name: Rebekah, Grace
name: Zachariah, Anand
name: Hansdak, Samuel George
name: Alex, Reginald
name: Chandiraseharan, Vignesh Kumar
name: Lenin, Audrin
name: Peter, John Victor
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Virology

description: It is unclear if the clinical presentation of poisoning with type 1 and type 2 pyrethroid compounds is different. This study was undertaken to detail the clinical profile and outcome of patients presenting with pyrethroid poisoning and to quantify serum pyrethroid levels. In this prospective study, patients were categorised as poisoning with type 1 pyrethroids or type 2 pyrethroids. Blood samples were sent for compound identification and quantification. Clinical features and outcomes were compared between the two groups. Factors associated with moderate and severe toxicity were explored using univariate logistic regression analysis and presented as odds ratio (OR) and 95% confidence intervals (CI). Type 1 pyrethroids were implicated in 16 patients and type 2 in 43 patients. The incidence of nausea and vomiting (81.2% vs. 81.3%) and tremor (37.5% vs. 32.6%) were similar in type 1 and type 2 poisoning; paraesthesia (6.2% vs. 32.6%, p = 0.04), hypersalivation (0% vs. 20.9%, p = 0.04), seizures (0% vs. 7%, p = 0.29) and depressed sensorium (0% vs. 18.6%, p = 0.03.) were observed more frequently in type 2 pyrethroid poisoning. Pyrethroids were detected in the serum samples of 24 patients; quantification was possible in 22 patients in whom serum levels ranged from 1.1 to 453 μg/ml. The compounds were undetectable in 35 patients. Two patients (lambda-cyhalothrin poisoning and cypermethrin poisoning) required intubation for low sensorium and respiratory distress. The median (interquartile range) duration of hospitalization was 12 (12–24) hours. All patients survived. Factors associated with moderate and severe toxicity included ingestion of a type 2 pyrethroid, lambda-cyhalothrin (OR 7.81, 95%CI 1.55–39.37, p = 0.01) and volume ingested (OR 1.01, 95%CI 1.00–1.02, p = 0.02). Patients with pyrethroid poisoning present predominantly with mild to moderate symptoms. Paraesthesia and hypersalivation are more frequent in type 2 poisoning. A favourable outcome can be expected.
Bayesian Gates for Reliable Logical Operations under Noisy Condition
Creators: name: Kobayashi, Tetsuya J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Other Computer Science (cs.OH)
subject: Quantum Physics (quant-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The reliability of logical operations is indispensable for the reliable operation of computational systems. Since the down-sizing of micro-fabrication generates non-negligible noise in these systems, a new approach for designing noise-immune gates is required. In this paper, we demonstrate that noise-immune gates can be designed by combining Bayesian inference theory with the idea of computation over a noisy signal. To reveal their practical advantages, the performance of these gates is evaluated in comparison with a stochastic resonance-based gate proposed previously. This approach for computation is also demonstrated to be better than a conventional one that conducts information transmission and computation separately.
description: 3figures + 3 supplementary figures
(501862) John Lambert
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Asymptotic analysis of the EPRL model with timelike tetrahedra
Creators: name: Kaminski, Wojciech
name: Kisielowski, Marcin
name: Sahlmann, Hanno
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We perform the stationary phase analysis of the vertex amplitude for the EPRL spin foam model extended to include timelike tetrahedra. We analyse both, tetrahedra of signature $---$ (standard EPRL), as well as of signature $+--$ (Hnybida-Conrady extension), in a unified fashion. However, we assume all faces to be of signature $--$. The stationary points of the extended model are described again by $4$-simplices and the phase of the amplitude is equal to the Regge action. Interestingly, in addition to the Lorentzian and Euclidean sectors there appear also split signature $4$-simplices.
description: v2: 97 pages, 4 figures, as published in CQG
Computational-based drug design of novel small molecules targeting p53-MDMX interaction
Creators: name: Egbemhenghe, Abel Ujaigbe
name: Aderemi, Olajide Enoch
name: Omotara, Bamidele Samson
name: Akhimien, Faith Iyayi
name: Osabuohien, Faith Osaretin
name: Adedapo, Habeebulah Ajibola
name: Temionu, Oluwakemi Rita
name: Egejuru, Winner Amaka
name: Ajala, Chinedum Favour
name: Ihunanya, Meejay Francis
name: Oluwafemi, Oluwatosin Oluwafunmilola
name: Onu, Chinyere Felicia Duncan
name: Ajibare, Abosede Christiana
name: Ddamulira, Christopher
name: Abalum, Justin Onyekachukwu
name: Afolayan, Olanrewaju Michael
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: The regulation of the p53 tumor suppressor pathway is critically dependent on the activity of Murine Double Minute 2 (MDM2) and Murine Double Minute X (MDMX) proteins. In certain types of cancer cells, excessive amount of MDMX can poly-ubiquitinate p53, which can result in its degradation, leading to a subsequent reduction in the levels of this protein. Therefore, the design of small-molecule inhibitors targeting the MDMX-p53 interaction has emerged as a promising strategy for cancer therapy. In this study, we employed computational techniques including pharmacophore modeling and molecular docking to identify three potential small molecule inhibitors (CID_25094615, CID_137634453, and CID_25094344) of the MDMX-p53 interaction from a PubChem database. Molecular dynamics of 100000 ps were conducted to assess the stability of the MDMX-inhibitor complexes. Our results showed that all three compounds exhibit stable binding with MDMX, with significantly lower root mean square deviation (RMSD) and fluctuation (RMSF) values than the control ligand, indicating superior stability. Additionally, the three compounds exhibit stronger intermolecular hydrogen bond (HBOND) interactions compared to the control, suggesting stronger stability. Overall, our findings highlight the potential of these compounds as lead candidates for the development of novel anticancer agents that target the MDMX-p53 interaction. Communicated by Ramaswamy H. Sarma
Polynomial time decodable codes for the binary deletion channel
Creators: name: Guruswami, Venkatesan
name: Li, Ray
Publisher: name: arXiv
Year: 2017
Subjects: subject: Information Theory (cs.IT)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: In the random deletion channel, each bit is deleted independently with probability $p$. For the random deletion channel, the existence of codes of rate $(1-p)/9$, and thus bounded away from $0$ for any $p < 1$, has been known. We give an explicit construction with polynomial time encoding and deletion correction algorithms with rate $c_0 (1-p)$ for an absolute constant $c_0 > 0$.
description: arXiv admin note: substantial text overlap with arXiv:1612.06335. The published version of this paper incorrectly states the alphabet size in Theorem 3.4. This version states the result correctly
Enterprise: the academic's challenge
Creators: name: Jones, Gillian
Publisher: name: Cardiff Metropolitan University
Year: 2022
Subjects: Higher education

description: The role of academic staff in Higher Education is complex and ever changing. The notion of the 'entrepreneurial university', a move towards diversifying a university's funding base has been instrumental in the transformation of this role. Role expectations are often confused by the interchangeable use of the terms 'enterprise', 'third mission' and 'innovation and engagement'. This can be compounded by a limited understanding of social enterprise and resistance to commercialising knowledge. This study is concerned with a critical exploration of engagement with enterprise in the Cardiff School of Education and was undertaken between 2009-2013 at Cardiff Metropolitan University.
 A case study approach was adopted using quantitative and qualitative methods for data collection. All sixty-three academic staff were invited to complete an on-line questionnaire that was provided in English and Welsh and forty-five responses were collated. Twenty-four staff were interviewed gathering viewpoints of academic staff, support staff, managers and senior managers.
 Results showed that the longer academic staff were employed at the university, the more likely they were to engage with enterprise. That is, there was an increasing awareness of the contribution of the skills of the entrepreneur to the University's strategic imperatives. Staff had a narrow understanding of enterprise, primarily focussing on income generation. Project managers, whilst supported in their role, often lacked an awareness of appropriate skills. Effective engagement required a marrying of enterprise projects to academic expertise and staff sought incentivisation.
 Themes that emerged from the data analysis led to the creation of an original model for enterprise, S4E. This has been based on four essential components which are: Strategic significance for Enterprise, Support for Enterprise, Synergy for Enterprise and Success for Enterprise. The recommendations have potential to inform practice in other academic schools and schools of education regionally, nationally and internationally.
Zero-Delay Source-Channel Coding with a One-Bit ADC Front End and Correlated Side Information at the Receiver
Creators: name: Varasteh, Morteza
name: Rassouli, Borzoo
name: Simeone, Osvaldo
name: Gunduz, Deniz
Publisher: name: arXiv
Year: 2017
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: Zero-delay transmission of a Gaussian source over an additive white Gaussian noise (AWGN) channel is considered with a one-bit analog-to-digital converter (ADC) front end and a correlated side information at the receiver. The design of the optimal encoder and decoder is studied for two performance criteria, namely, the mean squared error (MSE) distortion and the distortion outage probability (DOP), under an average power constraint on the channel input. For both criteria, necessary optimality conditions for the encoder and the decoder are derived. Using these conditions, it is observed that the numerically optimized encoder (NOE) under the MSE distortion criterion is periodic, and its period increases with the correlation between the source and the receiver side information. For the DOP, it is instead seen that the NOE mappings periodically acquire positive and negative values, which decay to zero with increasing source magnitude, and the interval over which the mapping takes non-zero values, becomes wider with the correlation between the source and the side information.
S1 Supplementary Data - Fung Characterization.pdf
Creators: name: Isawumi, Abiola
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 320203
subject: Clinical microbiology
classificationCode: 320207
subject: Emergency medicine
classificationCode: 320211
subject: Infectious diseases
classificationCode: 320212
subject: Intensive care
classificationCode: 320703
subject: Medical mycology
classificationCode: 320702
subject: Medical infection agents (incl. prions)
classificationCode: 310705
subject: Mycology
classificationCode: 310702
subject: Infectious agents
classificationCode: 310703
subject: Microbial ecology

description: Isolates of fungi from Ghanaian autopsy rooms