cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ToPs: Ensemble Learning with Trees of Predictors
Creators: name: Yoon, Jinsung
name: Zame, William R.
name: van der Schaar, Mihaela
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: We present a new approach to ensemble learning. Our approach constructs a tree of subsets of the feature space and associates a predictor (predictive model) - determined by training one of a given family of base learners on an endogenously determined training set - to each node of the tree; we call the resulting object a tree of predictors. The (locally) optimal tree of predictors is derived recursively; each step involves jointly optimizing the split of the terminal nodes of the previous tree and the choice of learner and training set (hence predictor) for each set in the split. The feature vector of a new instance determines a unique path through the optimal tree of predictors; the final prediction aggregates the predictions of the predictors along this path. We derive loss bounds for the final predictor in terms of the Rademacher complexity of the base learners. We report the results of a number of experiments on a variety of datasets, showing that our approach provides statistically significant improvements over state-of-the-art machine learning algorithms, including various ensemble learning methods. Our approach works because it allows us to endogenously create more complex learners - when needed - and endogenously match both the learner and the training set to the characteristics of the dataset while still avoiding over-fitting.
description: 12 pages, 2 figures
On the origin of the bi-drifting subpulse phenomenon in pulsars
Creators: name: Szary, Andrzej
name: van Leeuwen, Joeri
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The unique and highly unusual drift feature reported for PSR J0815+0939, wherein one component's subpulses drift in the direction opposite of the general trend, is a veritable challenge to pulsar theory. In this paper, we observationally quantify the drift direction throughout its profile, and find that the second component is the only one that exhibits "bi-drifting", meaning that only second component moves in the direction opposite of the others. We here present a model that shows that the observed bi-drifting phenomenon follows from the insight that the discharging regions, i.e. sparks, do not rotate around the magnetic axis per se, but rather around the point of electric potential extremum at the polar cap: minimum in the pulsar case ($\mathbfΩ \cdot \mathbf{B} < 0$) and maximum in the antipulsar case ($\mathbfΩ \cdot \mathbf{B} > 0$). We show that a purely dipolar surface magnetic field cannot exhibit bi-drifting behaviour, though certain non-dipolar configurations can. We can distinguish two types of solutions, with relatively low ($\sim 10^{12} \,{\rm G}$) and high ($\sim 10^{14} \,{\rm G}$) surface magnetic fields. Depending on the strength of the surface magnetic field, the radius of the curvature of magnetic field lines ranges from $10^{5} \,{\rm cm}$ to $10^{7}\,{\rm cm}$. Pulsar \J~allows us to gain an understanding of the polar-cap conditions essential for plasma generation processes in the inner acceleration region, by linking the observed subpulse shift to the underlying spark motion.
description: 14 pages, 21 figures, published in ApJ, editorial and erratum corrections added
Additional file 4: Figure S4. of Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border
Creators: name: Carrillo-HernĂĄndez, Marlen
name: Ruiz-Saenz, Julian
name: Villamizar, Lucy
name: GĂłmez-Rangel, Sergio
name: MartĂ­Nez-Gutierrez, Marlen
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Phylogenetic analysis of CHIKV strains circulating in Villa del Rosario. The evolutionary history was deduced using the Neighbor-Joining protocol for Env protein gene, using a fragment of 326 nucleotides. (DOCX 418 kb)
К ВОПРОСУ О ВНУТРЕННЕЙ ПРИЧИННОСТИ И ЕЕ СВЯЗИ С ОБЩЕЙ ПРОФИЛАКТИКОЙ: ФИЛОСОФСКИЙ АСПЕКТ
Creators: name: Евгений Семенович Жигарев
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: диалектический материализм
противоречие
причинность (внутренняя и внешняя)
диалектический идеализм
общая профилактика
устранение причин

description: Известно, что профилактическая деятельность органов внутренних дел направлена на сдерживание количественных и качественных показателей преступности, в первую очередь, путем устранения ее причин. Термин «устранить причины» обязан своему происхождению советскому времени, когда теория предупреждения преступности формировалась на основе монистического учения диалектического материализма. Именно тогда у криминологов сложилось весьма странное понимание сущности детерминантов, порождающих преступления. Цель этой статьи как раз состоит в том, чтобы обратить внимание сегодняшних криминологов на ошибочность понимания причинности в качестве объективной категории, которая якобы порождает преступность без прямого участия самой личности индивида, которую не устраняют, а изолируют от общества на определенное время.
Constructing Hopf braces
Creators: name: Agore, A. L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Algebra (math.QA)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics

description: We investigate Hopf braces, a concept recently introduced by Angiono, Galindo and Vendramin in connection to the quantum Yang-Baxter equation. More precisely, we propose two methods for constructing Hopf braces. The first one uses matched pairs of Hopf algebras while the second one relies on category theoretic tools.
ОСОБЕННОСТИ КВАЛИФИКАЦИИ ХИЩЕНИЙ С НЕЗАКОННЫМ ПРОНИКНОВЕНИЕМ В ИНОЕ ХРАНИЛИЩЕ (НА ОСНОВЕ ОБОБЩЕНИЯ МАТЕРИАЛОВ СУДЕБНОЙ ПРАКТИКИ)
Creators: name: Галина Васильевна Журавлева
name: Наталия Анатольевна Карпова
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: уголовная ответственность за хищение
хранилище как место совершения преступления
незаконное проникновение
проблемы квалификации

description: Рассматриваются особенности квалификации хищений, сопряженных с незаконным проникновением в иное хранилище. Анализируются объективные признаки, характеризующие место совершения преступления — «иное хранилище» и способ совершения преступления — незаконность проникновения. Теоретические положения статьи подкрепляются анализом материалов существующей судебной практики. Вносятся предложения по совершенствованию практики применения уголовного закона.
Moduli spaces of representations of special biserial algebras
Creators: name: Carroll, Andrew T.
name: Chindris, Calin
name: Kinser, Ryan
name: Weyman, Jerzy
Publisher: name: arXiv
Year: 2017
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 16G20

description: We show that the irreducible components of any moduli space of semistable representations of a special biserial algebra are always isomorphic to products of projective spaces of various dimensions. This is done by showing that irreducible components of varieties of representations of special biserial algebras are isomorphic to irreducible components of products of varieties of circular complexes, and therefore normal, allowing us to apply recent results of the second and third authors on moduli spaces.
description: 14 pages. v2: various improvements thanks to referees' comments. Some numbering changes due to a lemma being removed. v3: minor improvements, final version to be published
ПРАВОВЫЕ ПОСЛЕДСТВИЯ НЕЗАКОННОГО ПОТРЕБЛЕНИЯ НАРКОТИЧЕСКИХ СРЕДСТВ, ПСИХОТРОПНЫХ ВЕЩЕСТВ ИЛИ ИХ АНАЛОГОВ
Creators: name: Наталья Николаевна Заливина
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: наркотические средства
психотропные вещества
криминализация
уголовная ответственность
легализация
наркотизация
марихуана
слабые наркотики

description: Рассматривается дискуссионный на сегодняшний день вопрос: необходима ли в России криминализация незаконного потребления наркотических средств и психотропных веществ или их аналогов. Проанализированы точки зрения ученых на данную проблематику; изучен зарубежный опыт уголовно-правовой регламентации действий, касающихся незаконного потребления наркотических средств, психотропных веществ или их аналогов; изложена собственная точка зрения по данному вопросу с учетом практики расследования уголовных дел, возбужденных по преступлениям, связанным с незаконным потреблением наркотических средств, психотропных веществ или их аналогов.
УЧЕТ ИСТОРИЧЕСКОГО И ЗАРУБЕЖНОГО ОПЫТА ПРИ СОВЕРШЕНСТВОВАНИИ СТ. 68 УК РФ «НАЗНАЧЕНИЕ НАКАЗАНИЯ ПРИ РЕЦИДИВЕ ПРЕСТУПЛЕНИЙ»
Creators: name: Владимир Геннадьевич Кокорев
name: Лейла Фатуллаевна Аскерова
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: повторение преступлений
рецидивист
назначение наказания при рецидиве преступлений
специальный рецидив
уголовное законодательство
уголовная политика

description: Дается характеристика рецидива, отражаются статистические данные о количестве рецидива совершаемых преступлений от общего числа зарегистрированных преступлений и вынесенных обвинительных приговоров. Рассматривается отечественный опыт назначения наказания за рецидив, подчеркивается, что в дореволюционной России устанавливалось дифференцированное наказание за специальный рецидив, имеющий место и в УК РСФСР. Обращается внимание на зарубежный опыт некоторых стран по регламентации особенностей назначения наказания за рецидив. В соответствии с проводимой уголовной политикой автор приходит к выводу о необходимости введения в уголовный закон Российской Федерации такого института, как административная преюдиция — в ст. 68 УК РФ предусмотреть дифференциацию наказания в зависимости от вида рецидива.
Additional file 1: of The economic impact of sight loss and blindness in the UK adult population
Creators: name: Pezzullo, Lynne
name: Streatfeild, Jared
name: Simkiss, Philippa
name: Shickle, Darren
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: The economic impact of sight loss and blindness in the UK adult population â prevalence rates by age, gender, ethnicity and severity. This additional file provides a detailed overview of methods to estimate prevalence, any assumptions and the prevalence data sources underlying this research article. (DOCX 47 kb)
[Puchita : No sé si hoy ha ocurrido algún hecho histórico.]
Creators: name: Manuel, Vázquez Portal
name: Vázquez Portal, Manuel
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: Prison de Aguadores
Lutte politique

description: Destinataire : Huerga Cedeño, Yolanda
description: Description : Lettre de Vázquez Portal à son épouse. L'auteur de la lettre commence par une déclaration d'amour à sa femme. Il évoque ses conditions de détention, la privation de liberté, la pensée, les valeurs, l'opinion générale, le naufrage politique, la souffrance et le futur de Cuba.
description: Notes : Lettre envoyée depuis la Prison de Aguadores. Les pages sont numérotées de 1/4 à 4/4.
description: Source: Cote : MVP-B-2003-09-20
description: Source: Localisation du document : États-Unis, Miami (Floride)
ОСНОВНЫЕ КРИМИНАЛЬНЫЕ ТЕНДЕНЦИИ В СФЕРЕ РАЗВИТИЯ НОВЫХ ЭКОНОМИЧЕСКИХ ОТНОШЕНИЙ
Creators: name: Александр Макарович Никитин
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: экономика
капитал
государство
организованная преступная группа
предупреждение

description: Рассматриваются основные криминальные тенденции в сфере экономики государства. Анализируется преступная деятельность в области рынка, бизнеса, кредитно-финансовых отношений, а также влияние организованной преступности на такие процессы.
The Correlations of Barley Vitality and Storage Reserve Mobilization during Early Germination
Creators: name: Hu, Shumin
name: Qin, Qingqing
name: Liu, Jia
name: Yin, Hua
name: Meng, Qingshang
name: Yu, Junhong
name: Huang, Shuxia
name: Ma, Zengxin
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: The elucidation of the genetic relationship about storage reserve mobilization and enzymatic activity during barley germination is of particular importance for breeding and malt production. In addition to plant hormones such as gibberellic acid (GA) and abscisic acid (ABA), recent research has highlighted the importance of reactive oxygen species (ROS) signaling with hydrolase induction and plant growth. In this study, the correlation of barley vitality and mobilization of storage reserves during early seed germination was investigated. The activity of important hydrolases, as well as ROS-producing NADPH (nicotinamide adenine dinucleotide phosphate) oxidases, was monitored between six different cultivars. Associated gene expression from imbibition to germination was also analyzed by correlation analysis and cluster analysis. During early germination, the activities of α-amylase, limit dextrinase, and β-glucanase had significant positive correlations with each other and affected seed germination. Gene expression analysis showed that RbohB1 and RbohF1 (NADPH oxidases) had strong correlations with AMY1 (α-amylase) and LD (limit dextrinase). The GA synthesis gene GA3ox2 was found to have a significant correlation with protease genes Cys (cysteine protease) and Ser (serine protease), while the ABA synthesis gene NCED1 (nine-cis-epoxycarotenoid dioxygenase) had significant negative correlations with Cys and GA3ox2. Gene expression and enzyme assays indicated that NADPH oxidase, α-amylase, and limit dextrinase correlated well with barley vitality during early germination. The expression of the GA synthesis genes correlated well with glucanase and protease. These results provide information about barley gene regulation by analyzing correlations between genes.
БЕСПОМОЩНОЕ СОСТОЯНИЕ ПОТЕРПЕВШЕГО КАК КВАЛИФИЦИРОВАННЫЙ ВИД УБИЙСТВА: ОТДЕЛЬНЫЕ ВОПРОСЫ КВАЛИФИКАЦИИ
Creators: name: Юлия Владимировна Никонорова
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: квалифицированные виды убийства
беспомощное состояние
сон потерпевшего
состояние опьянения потерпевшего
престарелый

description: Рассматривается состав преступления, предусмотренный п. «в» ч. 2 ст. 105 УК РФ, а также вопрос о возможности привлечения лица, совершившего убийство потерпевшего, находящегося в состоянии сна, состоянии алкогольного опьянения, а также в престарелом возрасте, к уголовной ответственности по п. «в» ч. 2 ст. 105 УК РФ.
Formation of Massive, Dense Cores by Cloud-Cloud Collisions
Creators: name: Takahira, Ken
name: Shima, Kazuhiro
name: Tasker, Elizabeth J.
name: Habe, Asao
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We performed sub-parsec ($\sim$ 0.014 pc) scale simulations of cloud-cloud collisions of two idealized turbulent molecular clouds (MCs) with different masses in the range of $0.76 - 2.67 \times 10^4$M$_{\odot}$ and with collision speeds of 5 $-$ 30 km/s. Those parameters are larger than Takahira, Tasker and Habe (2014) (paper I) in which the colliding system showed a partial gaseous arc morphology that supports the NANTEN observations of objects indicated to be colliding MCs by numerical simulations. Gas clumps with density greater than $10^{-20}$ g cm$^{-3}$ were identified as pre-stellar cores and tracked through the simulation to investigate the effect of mass of colliding clouds and collision speeds on the resulting core population. Our results demonstrate that smaller cloud property is more important for results of cloud cloud collisions. The mass function of formed cores can be approximated by a power law relation with index $γ$ = -1.6 in slower cloud cloud collisions ($v \sim 5 $ km/s), in good agreement with observation of MCs. A faster relative velocity increases the number of cores formed in the early stage of collisions and shortens gas accretion phase of cores in the shocked region, leading to suppression of core growth. The bending point appears in the high mass part of the core mass function and the bending point mass decreases with increasing of the collision velocity for the same combination of colliding clouds. The high mass part of the core mass function than the bending point mass can be approximated by a power law with $γ$ = -2.3 that is very similar to the power index of the massive part of the observed initial stellar mass function. We discuss implication of our results for the massive star formation in our Galaxy.
description: 15 pages, 15 figures, PASJ in press
Additional file 9: of HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors
Creators: name: Daemen, Anneleen
name: Manning, Gerard
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Characterization of the HER2 amplicon and HER2 co-amplification in breast cancer. (A) Chromosomal instability, shown as the number of breaks per kb per autosome, is higher in HER2A than non-HER2A TCGA tumors, with one-sided t test p values per chromosome ranging from 0.37 (chr 5) to 5e-26 (chr 17), and <0.05 for 17/22 autosomes. (B) Copy number levels in 106 HER2A TCGA breast tumors, for genes on chromosome 17 from 35 Mb to 40 Mb (ordered by genomic location). The core HER2 amplicon on top is shown in green, the broad HER2 amplicon in yellow, and genes outside of the broad HER2 amplicon on 17q in magenta. Shown in green on top is correlation between copy number and expression (log2 nRPKM + 1) for each gene across the 864 tumors. (C) HER2 amplicon profile in 133 HER2A Metabric tumors. See Fig. 2a legend for details. (D) Four HER2A TCGA breast tumors show 17q arm-level amplification without additional HER2 focality. Shown are total copy number levels for genes on 17q from 35 Mb to 40 Mb (colored as per panel (B)). (E) Fisher’s exact FDR p values for co-amplification of genes with HER2 in 1971 tumors from TCGA and Metabric cohorts. Amplification was defined as 4 or more ploidy-corrected copies. Chromosomes are colored alternatingly in black and gold. (F, G) We detected two regions with germline micro-deletions or micro-gains in normal breast tissue from TCGA: 34.4–34.6 Mb and 44.1–44.8 Mb. These regions are defined as loci with copy number levels either >2.4 or <1.6 in at least 5% of normal breast samples, and were removed from Fig. 2b for visual purposes. Shown are copy number levels in 765 matched normal breast samples, for all genes on chromosome 17, before (F) and after (G) removal of those two regions. (PDF 969 kb)
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Cart. 192 (11 H 77), 295 folios, f. 0123v
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0123v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0123v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
УГОЛОВНОЕ ЗАКОНОДАТЕЛЬСТВО ВЕЛИКОБРИТАНИИ ОБ ОТВЕТСТВЕННОСТИ ЗА ПРЕСТУПЛЕНИЯ ПРОТИВ ОБЩЕСТВЕННОЙ НРАВСТВЕННОСТИ
Creators: name: Роман Борисович Осокин
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: преступления против общественной нравственности
уголовное законодательство Великобритании
проституция
жестокое обращение с животными

description: Рассмотрены особенности регламентации уголовной ответственности за преступления против общественной нравственности. Проведен анализ общих и отличительных признаков уголовной ответственности за совершение данных преступлений по законодательству России и Великобритании.
Interpolation inequalities and spectral estimates for magnetic operators
Creators: name: Dolbeault, Jean
name: Esteban, Maria J.
name: Laptev, Ari
name: Loss, Michael
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We prove magnetic interpolation inequalities and Keller-Lieb-Thir-ring estimates for the principal eigenvalue of magnetic Schr{ö}dinger operators. We establish explicit upper and lower bounds for the best constants and show by numerical methods that our theoretical estimates are accurate.
ОРГАНЫ ВНУТРЕННИХ ДЕЛ В СИСТЕМЕ ГОСУДАРСТВЕННОЙ ВЛАСТИ В РОССИЙСКОЙ ФЕДЕРАЦИИ
Creators: name: Артур Левонович Миронов
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: Российская Федерация
законодательство
нормативный правовой акт
федеральный закон РФ
Кодекс РФ об административных правонарушениях от 20 декабря 2001 г.
Федеральный закон РФ «О полиции» от 28 января 2011 г.
органы внутренних дел
полиция
правоохранительный орган
система правоохранительных органов
государственная власть
органы исполнительной власти

description: На основе анализа юридической литературы и законодательства об органах внутренних дел и их месте в системе государственной власти Российской Федерации высказано несколько суждений: государственная власть в Российской Федерации осуществляется законодательными, исполнительными и судебными государственными органами; в систему государственных органов исполнительной ветви власти включаются органы внутренних дел; помимо системы государственных органов исполнительной ветви власти органы внутренних дел входят и в систему правоохранительных органов; конкуренция статусов органов внутренних дел должна разрешаться в пользу принадлежности к правоохранительным органам.
Estimating single molecule conductance from spontaneous evolution of a molecular contact
Creators: name: Gil, M.
name: Malinowski, T.
name: Iazykov, M.
name: Klein, H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present an original method to estimate the conductivity of a single molecule anchored to nanometric-sized metallic electrodes, using a Mechanically Controlled Break Junction (MCBJ) operated at room temperature in liquid. We record the conductance through the metal / molecules / metal nanocontact while keeping the metallic electrodes at a fixed distance. Taking advantage of thermal diffusion and electromigration, we let the contact naturally explore the more stable configurations around a chosen conductance value. The conductance of a single molecule is estimated from a statistical analysis of raw conductance and conductance standard deviation data for molecular contacts containing up to 14 molecules. The single molecule conductance values are interpreted as time-averaged conductance of an ensemble of conformers at thermal equilibrium.
description: 25 pages, 6 figures
ИСТОРИКО-ПРАВОВОЙ АНАЛИЗ ВОЗНИКНОВЕНИЯ И РАЗВИТИЯ ЗАКОНОДАТЕЛЬСТВА РОССИЙСКОГО ГОСУДАРСТВА ОБ ОТВЕТСТВЕННОСТИ ЗА ТОРГОВЛЮ ЛЮДЬМИ
Creators: name: Андрей Владимирович Староверов
Publisher: name: Вестник Московского университета МВД России
Year: 2019
Subjects: торговля людьми
подневольное состояние
противодействие торговле людьми
рабский труд
сексуальная эксплуатация
личная свобода

description: Раскрываются причины возникновения в России норм об ответственности за торговлю людьми; показывается генезис развития законодательства российского государства о такой ответственности, начиная от раннего средневековья и заканчивая настоящим временем; проводится авторская классификация периодов течения данного процесса.
Mézières Method as a practice of embodiment in patients with low back pain: a mixed study
Creators: name: Alfonso-Mora, Margareth Lorena
name: Guerra-Balic, Miriam
name: Sánchez-Martín, Ricardo
name: Pedraza-Gómez, Zandra
name: Ramírez-Moreno, José
name: Castellanos-Garrido, Adriana Lucía
name: Zambrano-Cristancho, Leidy Katerin
name: Varona, María Leonor Rengifo
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: The objectives of this study were to determine the effects of the Mézières Method (MM) on pain and disability related to low back pain (LBP), compared to a program of heat, massage and exercise, and to understand the meaning of the bodily experience with the MM. Mixed methods convergent parallel design, combining an equivalent randomized clinical trial with a qualitative phenomenological approach. Sixty-one participants aged 18–65 years with chronic non-specific LBP lasting more than 3 months. Patients were randomized into two groups: the MM group (n = 29) and the comparison group (CG) who received heat, massage plus flexibility and strengthening exercises (n = 31). MM and CG participants underwent 10 one-hour physical therapy sessions over a 5-week period and were evaluated three times: pre-intervention, post-intervention and follow-up at 6 weeks after the end of treatment. Both groups reported positive effects on LBP . MM group showed superior effects in pain relief in the short term (Cohen’s D 0.80; p = 0.004). Participants interpreted the interaction with the MM as a teaching–learning process that allowed body awareness. Both treatment were similarly beneficial but MM had superior effects on pain in the short term. MM is perceived by the participants as a teaching–learning process focused on body awareness that facilitate effective management of LBP.
Quantum spin liquid signatures in Kitaev-like frustrated magnets
Creators: name: Gohlke, Matthias
name: Wachtel, Gideon
name: Yamaji, Youhei
name: Pollmann, Frank
name: Kim, Yong Baek
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Motivated by recent experiments on $α$-RuCl$_3$, we investigate a possible quantum spin liquid ground state of the honeycomb-lattice spin model with bond-dependent interactions. We consider the $K-Γ$ model, where $K$ and $Γ$ represent the Kitaev and symmetric-anisotropic interactions between spin-1/2 moments on the honeycomb lattice. Using the infinite density matrix renormalization group (iDMRG), we provide compelling evidence for the existence of quantum spin liquid phases in an extended region of the phase diagram. In particular, we use transfer matrix spectra to show the evolution of two-particle excitations with well-defined two-dimensional dispersion, which is a strong signature of quantum spin liquid. These results are compared with predictions from Majorana mean-field theory and used to infer the quasiparticle excitation spectra. Further, we compute the dynamical structure factor using finite size cluster computations and show that the results resemble the scattering continuum seen in neutron scattering experiments on $α$-RuCl$_3$. We discuss these results in light of recent and future experiments.
description: Modified manuscript: 17 pages, 21 figures
Small-Scale Challenges to the $Λ$CDM Paradigm
Creators: name: Bullock, James S.
name: Boylan-Kolchin, Michael
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The dark energy plus cold dark matter ($Λ$CDM) cosmological model has been a demonstrably successful framework for predicting and explaining the large-scale structure of Universe and its evolution with time. Yet on length scales smaller than $\sim 1$ Mpc and mass scales smaller than $\sim 10^{11} M_{\odot}$, the theory faces a number of challenges. For example, the observed cores of many dark-matter dominated galaxies are both less dense and less cuspy than naively predicted in $Λ$CDM. The number of small galaxies and dwarf satellites in the Local Group is also far below the predicted count of low-mass dark matter halos and subhalos within similar volumes. These issues underlie the most well-documented problems with $Λ$CDM: Cusp/Core, Missing Satellites, and Too-Big-to-Fail. The key question is whether a better understanding of baryon physics, dark matter physics, or both will be required to meet these challenges. Other anomalies, including the observed planar and orbital configurations of Local Group satellites and the tight baryonic/dark matter scaling relations obeyed by the galaxy population, have been less thoroughly explored in the context of $Λ$CDM theory. Future surveys to discover faint, distant dwarf galaxies and to precisely measure their masses and density structure hold promising avenues for testing possible solutions to the small-scale challenges going forward. Observational programs to constrain or discover and characterize the number of truly dark low-mass halos are among the most important, and achievable, goals in this field over then next decade. These efforts will either further verify the $Λ$CDM paradigm or demand a substantial revision in our understanding of the nature of dark matter.
description: 47 pages, 15 figures. Draft of a review to appear in ARAA, volume 55. See http://www.annualreviews.org/doi/10.1146/annurev-astro-091916-055313 for updated version. Final online publication date: August 18, 2017. v2: corrected coefficients for Eqs. 8-10
Community Discovery in Dynamic Networks: a Survey
Creators: name: Rossetti, Giulio
name: Cazabet, Rémy
Publisher: name: arXiv
Year: 2017
Subjects: subject: Social and Information Networks (cs.SI)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences
subject: A.1; E.1; G.2.2; I.5.3

description: Networks built to model real world phenomena are characeterised by some properties that have attracted the attention of the scientific community: (i) they are organised according to community structure and (ii) their structure evolves with time. Many researchers have worked on methods that can efficiently unveil substructures in complex networks, giving birth to the field of community discovery. A novel and challenging problem started capturing researcher interest recently: the identification of evolving communities. To model the evolution of a system, dynamic networks can be used: nodes and edges are mutable and their presence, or absence, deeply impacts the community structure that composes them. The aim of this survey is to present the distinctive features and challenges of dynamic community discovery, and propose a classification of published approaches. As a "user manual", this work organizes state of art methodologies into a taxonomy, based on their rationale, and their specific instanciation. Given a desired definition of network dynamics, community characteristics and analytical needs, this survey will support researchers to identify the set of approaches that best fit their needs. The proposed classification could also help researchers to choose in which direction should future research be oriented.
The best constant in the embedding of $W^{N,1}({\mathbb R}^N)$ into $L^\infty({\mathbb R}^N)$
Creators: name: Shafrir, Itai
Publisher: name: arXiv
Year: 2017
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: Primary 46E35, Secondary 35A23

description: We compute the best constant in the embedding of $W^{N,1}({\mathbb R}^N)$ into $L^\infty({\mathbb R}^N)$, extending a result of Humbert and Nazaret in dimensions one and two to any $N$. The main tool is the identification of $\log |x|$ as a fundamental solution of a certain elliptic operator of order $2N$.
Additional file 8: Table S3. of Inferring synteny between genome assemblies: a systematic evaluation
Creators: name: Liu, Dang
name: Hunt, Martin
name: Isheng Tsai
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology

description: Assembly statistics among Caenorhabditis species and Strongyloides species including ALLMAPS results. (DOCX 1Â kb)
Independent prognostic biomarker FERMT3 associated with immune infiltration and immunotherapy response in glioma
Creators: name: Zhuo, Shenghua
name: Tang, Caiying
name: Yang, Liangwang
name: Chen, Zhimin
name: Chen, Taixue
name: Wang, Kai
name: Yang, Kun
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Adult glioma progresses rapidly and has a poor clinical outcome. The focal adhesion protein Kindlin-3 (encoded by the FERMT3 gene) participates in tumor development, drug resistance, and progression. However, the relationship between Kindlin-3 and glioma prognosis or immune microenvironment is poorly understood. We comprehensively analyzed the expression, prognostic value, mutation landscape, functional enrichment, immune infiltration, and therapeutic role of FERMT3 in glioma using multiple datasets and validated Kindlin-3 expression in clinical tissue specimens by immunohistochemistry and multiple immunofluorescence staining. FERMT3 is an independent predictor of glioma prognosis and is highly expressed in glioblastoma tissues. Functional enrichment analyses indicated that FERMT3 participates in multiple immune-related pathways such as immune response and cytokine production. Furthermore, FERMT3 expression was positively correlated with the infiltration of several immune cells, immune scores, and the expression of genes related to immune checkpoints. Further analyses revealed that overexpression of FERMT3 was linked to a better response to anti-PD1 therapy. Data from single-cell RNA-seq reveal that FERMT3 was largely expressed in microglial cells and tissue-resident macrophages. Multiple immunofluorescence staining confirmed the overexpression of Kindlin-3 in the glioma-associated microglia/macrophages (GAMs). The findings of this study provide a new perspective on the role of Kindlin-3 in glioma and may have a significant impact on the discovery of novel biomarkers and targeting of GAMs in the future.
Jean-Paul Claverie (conseiller de mécénat du groupe LVMH)
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (6 pages). Pièce jointe : extrait de J. Leibowitch, "Pour en finir avec le sida".
IN03095 Dim̆bulā-gala Mārā-vīdye Rock Inscription
Creators: name: Wickremasinghe, Don Martino de Zilva
Publisher: name: Zenodo
Year: 2020
Subjects: IN03095
Epigraphia Zeylanica
Dim̆bulā-gala
Dimbulagala

description: IN03095 Dim̆bulā-gala Mārā-vīdye Rock Inscription - Transcript and Translation Source: Wickremasinghe, Don Martino de Zilva. (1924). ‘No. 34. Dim̆bulā-gala: Mārā-vīdye Rock-Inscription,’ Epigraphia Zeylanica 2 (1912-27), pp. 194-202.
Energy preserving model order reduction of the nonlinear Schrödinger equation
Creators: name: Karasözen, Bülent
name: Uzunca, Murat
Publisher: name: arXiv
Year: 2017
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65P10, 65M60, 365Q55, 37M15, 93A15

description: An energy preserving reduced order model is developed for two dimensional nonlinear Schrödinger equation (NLSE) with plane wave solutions and with an external potential. The NLSE is discretized in space by the symmetric interior penalty discontinuous Galerkin (SIPG) method. The resulting system of Hamiltonian ordinary differential equations are integrated in time by the energy preserving average vector field (AVF) method. The mass and energy preserving reduced order model (ROM) is constructed by proper orthogonal decomposition (POD) Galerkin projection. The nonlinearities are computed for the ROM efficiently by discrete empirical interpolation method (DEIM) and dynamic mode decomposition (DMD). Preservation of the semi-discrete energy and mass are shown for the full order model (FOM) and for the ROM which ensures the long term stability of the solutions. Numerical simulations illustrate the preservation of the energy and mass in the reduced order model for the two dimensional NLSE with and without the external potential. The POD-DMD makes a remarkable improvement in computational speed-up over the POD-DEIM. Both methods approximate accurately the FOM, whereas POD-DEIM is more accurate than the POD-DMD.
Assessing vaccine effectiveness for varicella in Wuxi, China: a time-series analysis
Creators: name: Wang, Lingling
name: Yang, Xu
name: Wang, Xuwen
name: Shi, Ping
name: Zhang, Xuhui
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: The varicella vaccine is not included in the national childhood immunization schedules in China. Varicella epidemics and outbreaks are frequently reported, and the evidence for the effectiveness of the varicella vaccine remains unclear. The aim of this study was to investigate varicella vaccine effectiveness in Wuxi, China. Varicella surveillance data were extracted from the China Information System for Disease Control and Prevention, and vaccination data were obtained from the Vaccination Integrated Service Management Information System of Jiangsu Province, China. Time-series analysis approaches were used to estimate varicella vaccine effectiveness. A total of 16,093 varicella cases among children aged 1–6 years between January 2016 and December 2020 were analysed. A total of 217,297 children completed a two-dose varicella vaccination series. Compared with districts with lower vaccination rates, districts in Wuxi with higher varicella vaccination rates had a lower proportion of cases (p < 0.001). In the time-series approach, 0.8% fewer varicella cases were associated with a 1% increase in the two-dose varicella vaccination rate (p < 0.001), and similar effects were found in both the male and female populations. Two-dose varicella vaccination was recommended as an effective health intervention to prevent varicella in Wuxi, China. Varicella vaccination is urgently needed in routine childhood immunisation programs. The introduction of two-dose varicella vaccination was an effective intervention to prevent varicella in Wuxi, China. Varicella vaccination is urgently needed in routine childhood immunization programmes.
Additional file 3: Figure S3. of Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border
Creators: name: Carrillo-HernĂĄndez, Marlen
name: Ruiz-Saenz, Julian
name: Villamizar, Lucy
name: GĂłmez-Rangel, Sergio
name: MartĂ­Nez-Gutierrez, Marlen
Publisher: name: figshare
Year: 2018
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Phylogenetic analysis of DENV-3 strains isolated in Villa del Rosario. The evolutionary history was deduced by using the Neighbor-Joining protocol for gene pr-M protein, using a fragment of 430 nucleotides. (DOCX 392 kb)
Black Hole Mergers in Galactic Nuclei Induced by the Eccentric Kozai-Lidov Effect
Creators: name: Hoang, Bao-Minh
name: Naoz, Smadar
name: Kocsis, Bence
name: Rasio, Frederic A.
name: Dosopoulou, Fani
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Nuclear star clusters around massive black holes are expected to be abundant in stellar mass black holes and black hole binaries. These binaries form a hierarchical triple system with the massive black hole at the center. Gravitational perturbations from the massive black hole can cause high eccentricity excitation. During this process, the eccentricity may approach unity, and the pericenter distance may become sufficiently small that gravitational wave emission drives the binary to merge. In this paper, we consider a simple proof of concept and explore the effect of the eccentric Kozai-Lidov mechanism for unequal mass binaries. We perform a set of Monte Carlo simulations on BH-BH binaries in galactic nuclei with quadrupole and octupole-level secular perturbations, general relativistic precession, and gravitational wave emission. For a nominal number of steady-state BH-BH binaries, our model gives a total merger rate $\sim 1 - 3$$Gpc^{-3} yr^{-1}$, depending on the assumed density profile. Thus, our model potentially competes with other dynamical mechanisms, such as the dynamical formations and mergers of BH binaries in globular clusters or dense nuclear clusters without a massive black hole. We provide predictions for the distributions of these LIGO sources in galactic nuclei.
description: 10 pages, 12 figures, accepted to ApJ
Network pharmacology combined with molecular docking and experimental validation to explore the potential mechanism of Cinnamomi ramulus against ankylosing spondylitis
Creators: name: Wei, Wendi
name: Wu, Shaofeng
name: Zhou, Chenxing
name: Chen, Tianyou
name: Zhu, Jichong
name: Feng, Sitan
name: Zhan, Xinli
name: Liu, Chong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Cinnamomi ramulus (C. ramulus) is frequently employed in the treatment of ankylosing spondylitis (AS). However, the primary constituents, drug targets, and mechanisms of action remain unidentified. In this study, various public databases and online tools were employed to gather information on the compounds of C. ramulus, drug targets, and disease targets associated with ankylosing spondylitis. The intersection of drug targets and disease targets was then determined to identify the common targets, which were subsequently used to construct a protein-protein interaction (PPI) network using the STRING database. Network analysis and the analysis of hub genes and major compounds were conducted using Cytoscape software. Furthermore, the Metascape platform was utilized for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. Molecular docking studies and immunohistochemical experiments were performed to validate the core targets. The network analysis identified 2-Methoxycinnamaldehyde, cinnamaldehyde, and 2-Hydroxycinnamaldehyde as the major effective compounds present in C. ramulus. The PPI network analysis revealed PTGS2, MMP9, and TLR4 as the most highly correlated targets. GO and KEGG analyses indicated that C. ramulus exerts its therapeutic effects in ankylosing spondylitis through various biological processes, including the response to hormones and peptides, oxidative stress response, and inflammatory response. The main signaling pathways involved were IL-17, TNF, NF-kappa B, and Toll-like receptor pathways. Molecular docking analysis confirmed the strong affinity between the key compounds and the core targets. Additionally, immunohistochemical analysis demonstrated an up-regulation of PTGS2, MMP9, and TLR4 levels in ankylosing spondylitis. This study provides insights into the effective compounds, core targets, and potential mechanisms of action of C. ramulus in the treatment of ankylosing spondylitis. These findings establish a solid groundwork for future fundamental research in this field.
Additional file 8: of HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors
Creators: name: Daemen, Anneleen
name: Manning, Gerard
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Identification of ER- tumors that are AR-driven. (A) Top 10 C2 gene sets from MSigDB [22] enriched among genes differentially expressed between HER2E and other breast tumors. See Additional file 7B for the full list of C2 gene sets. (B) Overlap in number of genes between the top 10 C2 gene sets and androgen responsive gene sets (from Additional file 7B). (C) AR-ness score across PAM50 subtypes for 205 breast tumors from Metabric that are ER- by IHC. AR-ness score is calculated as the difference in average z-scored expression of 14 positive signature genes and average z-scored expression of 31 negative signature genes. Tumors are colored by HER2A status. (D) AR protein levels in 90 ER- TCGA tumors by AR-ness score. (E) Kaplan-Meier curve of overall survival (OS) in 977 Metabric tumors with a median follow up of 7.3 years, divided into 5 groups based on ER IHC status, PAM50 subtype, and AR activity (positive vs. negative AR-ness score). OS was truncated to 17 years of follow up. (F) Left, Kaplan-Meier curve of OS in 57 ER- HER2A tumors from Metabric, divided by AR-ness score. Right, Kaplan-Meier curve of OS in 121 ER- non-HER2A tumors from Metabric, divided by AR-ness score. OS was truncated to 17 years of follow up. (PDF 167 kb)