cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The feasibility and acceptability of a task-shifted intervention for perinatal depression among women living with HIV in Malawi: a qualitative analysis
Creators: name: Go, V.F.
name: Kutengule, A.
name: Dussault, J.M.
name: LeMasters, K.
name: Meltzer-Brody, S.
name: Kulisewa, K.
name: Hosseinipour, M.C.
name: Mphonda, S.M
name: Midiani, D.
name: Gaynes, B.N.
name: Udedi, M
name: Pence, B.W
name: Bengtson, A.M
Publisher: name: BioMed Central Ltd
Year: 2022

description: Background: Perinatal depression (PND) is prevalent and negatively impacts HIV care among women living with HIV (WLHIV), yet PND remains under-identified in Malawian WLHIV. Accordingly, this formative study explored perceptions of the feasibility and acceptability of an integrated, task-shifted approach to PND screening and treatment in maternity clinics. Methods: We completed consecutive PND screenings of HIV+ women attending pre- or post-natal appointments at 5 clinics in Lilongwe district, Malawi. We conducted in-depth interviews with the first 4-5 women presenting with PND per site (n = 24 total) from July to August 2018. PND classification was based on a score ≥ 10 on the Edinburgh Postnatal Depression Scale (EPDS). We conducted 10 additional in-depth interviews with HIV and mental health providers at the 5 clinics. Results: Most participants endorsed the feasibility of integrated PND screening, as they believed that PND had potential for significant morbidity. Among providers, identified barriers to screening were negative staff attitudes toward additional work, inadequate staffing numbers and time constraints. Suggested solutions to barriers were health worker training, supervision, and a brief screening tool. Patient-centered counselling strategies were favored over medication by WLHIV as the acceptable treatment of choice, with providers supporting the role of medication to be restricted to severe depression. Providers identified nurses as the most suitable health workers to deliver task-shifted interventions and emphasized further training as a requirement to ensure successful task shifting. Conclusion: Improving PND in a simple, task-shifted intervention is essential for supporting mental health among women with PND and HIV. Our results suggest that an effective PND intervention for this population should include a brief, streamlined PND screening questionnaire and individualized counselling for those who have PND, with supplemental support groups and depression medication readily available. These study results support the development of a PND intervention to address the gap in treatment of PND and HIV among WLHIV in Malawi.
Connections on the State-Space over Conformal Field Theories
Creators: name: Ranganathan, K.
name: Sonoda, H.
name: Zwiebach, B.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Motivated by the problem of background independence of closed string field theory we study geometry on the infinite vector bundle of local fields over the space of conformal field theories (CFT's). With any connection we can associate an excluded domain $D$ for the integral of marginal operators, and an operator one-form $ω_μ$. The pair $(D, ω_μ)$ determines the covariant derivative of any correlator of local fields. We obtain interesting classes of connections in which $ω_μ$'s can be written in terms of CFT data. For these connections we compute their curvatures in terms of four-point correlators, $D$, and $ω_μ$. Among these connections three are of particular interest. A flat, metric compatible connection $\HG$, and connections $c$ and $\bar c$ having non-vanishing curvature, with $\bar c$ being metric compatible. The flat connection cannot be used to do parallel transport over a finite distance. Parallel transport with either $c$ or $\bar c$, however, allows us to construct a CFT in the state space of another CFT a finite distance away. The construction is given in the form of perturbation theory manifestly free of divergences.
description: 54pp. MIT-CTP-2193
H.E.S.S. observations following multi-messenger alerts in real-time
Creators: name: Schüssler, Fabian
name: Backes, M.
name: Balzer, A.
name: Brun, F.
name: Füßling, M.
name: Hoischen, C.
name: Lenain, J. -P.
name: Lypova, I.
name: Ohm, S.
name: Parsons, D.
name: Pühlhofer, G.
name: Reimer, A.
name: Rowell, G.
name: Seglar-Arroyo, M.
name: Taylor, A. M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The H.E.S.S. Imaging Air Cherenkov Telescope system is, due to its fast reaction time and its comparably low energy threshold, very well suited to perform follow-up observations of detections at other wavelengths or other messengers like high-energy neutrinos and gravitational waves. These advantages are utilized optimally via a fully automatized system reacting to alerts from various partner observatories covering various wavelengths and astrophysical messengers. In this contribution we'll provide an overview and present recent results from H.E.S.S. programs to follow up on multi-wavelength and multi-messenger alerts. To illustrate the capabilities of the system we present several real-time ToO observations searching for high-energy gamma-ray emission in coincidence with high-energy neutrinos detected by the IceCube and ANTARES neutrino telescopes and outline our program to search for gravitational wave counterparts.
description: Proceedings 35th International Cosmic Ray Conference (ICRC2017), Busan/South Korea
Additional file 2: of Effectiveness and sustainability of a structured group-based educational program (MEDIHEALTH) in improving medication adherence among Malay patients with underlying type 2 diabetes mellitus in Sarawak State of Malaysia: study protocol of a randomized controlled trial
Creators: name: Chuo Ting
name: Shahren Ahmad Zaidi Adruce
name: Hassali, Mohamed
name: Hiram Ting
name: Lim, Chien
name: Ting, Rachel Sing-Kiat
name: Jabar, Abu Abd
name: Nor Osman
name: Izzul Shuib
name: Shing Loo
name: Sim, Sui
name: Lim, Su
name: Morisky, Donald
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: MEDIHEALTH content and intervention mapping. (PDF 193Â kb)
The anisotropic non-equilibrium hydrodynamic attractor
Creators: name: Strickland, Michael
name: Noronha, Jorge
name: Denicol, Gabriel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We determine the dynamical attractors associated with anisotropic hydrodynamics (aHydro) and the DNMR equations for a 0+1d conformal system using kinetic theory in the relaxation time approximation. We compare our results to the non-equilibrium attractor obtained from exact solution of the 0+1d conformal Boltzmann equation, Navier-Stokes theory, and second-order Mueller-Israel-Stewart theory. We demonstrate that the aHydro attractor equation resums an infinite number of terms in the inverse Reynolds number. The resulting resummed aHydro attractor possesses a positive longitudinal to transverse pressure ratio and is virtually indistinguishable from the exact attractor. This suggests that kinetic theory involves not only a resummation in gradients (Knudsen number) but also a novel resummation in inverse Reynolds number. We also demonstrate that the DNMR result provides a better approximation to the exact kinetic theory attractor than Mueller-Israel-Stewart theory. Finally, we introduce a new method for obtaining approximate aHydro equations which relies solely on an expansion in inverse Reynolds number, carry out this expansion to third order, and compare these third-order results to the exact kinetic theory solution.
description: 25 pages, 7 figures
Refinement of protein-protein complexes in contact map space with metadynamics simulations
Creators: name: Pfeiffenberger, Erik
name: Bates, Paul A
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Structural Biology & Biophysics
Computational & Systems Biology

description: Accurate protein-protein complex prediction, to atomic detail, is a challenging problem. For flexible docking cases, current state-of-the-art docking methods are limited in their ability to exhaustively search the high dimensionality of the problem space. In this study, to obtain more accurate models, an investigation into the local optimization of initial docked solutions is presented with respect to a reference crystal structure. We show how physics-based refinement of protein-protein complexes in contact map space (CMS), within a metadynamics protocol, can be performed. The method uses 5 times replicated 10 ns simulations for sampling and ranks the generated conformational snapshots with ZRANK to identify an ensemble of n snapshots for final model building. Furthermore, we investigated whether the reconstructed free energy surface (FES), or a combination of both FES and ZRANK, referred to as CSα , can help to reduce snapshot ranking error.
Ab initio study of Li, Mg and Al insertion into rutile VO2: Fast diffusion and enhanced voltages
Creators: name: Kulish, Vadym V.
name: Koch, Daniel
name: Manzhos, Sergei
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Vanadium oxides are among the most promising materials that can be used as electrodes in rechargeable metal-ion batteries. In this work, we systematically investigate thermodynamic, electronic and kinetic properties associated with the insertion of Li, Mg and Al atoms in rutile VO2. Using first-principles calculations, we systematically study the structural evolution and voltage curves of LixVO2, MgxVO2 and AlxVO2 (0
Adaptation of a Problem-solving Program (Friendship Bench) to Treat Common Mental Disorders Among People Living With HIV and AIDS and on Methadone Maintenance Treatment in Vietnam: Formative Study
Creators: name: Tran, H.V.
name: Le, G.M.
name: Nguyen, M.X.
name: Gaynes, B.N
name: Pence, B.W.
name: Nong, H.T.T.
name: Landrum, K.R.
name: Filipowicz, T.R.
name: Tran, T.T.T.
name: Ho, H.T
name: Go, V.F
name: Verhey, R
name: Chibanda, D.
Publisher: name: JMIR Publications Inc.
Year: 2022

description: Background: The prevalence of common mental disorders (CMDs) among people living with HIV and people who inject drugs is high worldwide and in Vietnam. However, few evidence-informed CMD programs for people living with HIV who inject drugs have been adapted for use in Vietnam. We adapted the Friendship Bench (FB), a problem-solving therapy (PST)-based program that was successfully implemented among patients with CMDs in primary health settings in Zimbabwe and Malawi for use among people living with HIV on methadone maintenance treatment (MMT) with CMDs in Hanoi, Vietnam. Objective: This study aimed to describe the adaptation process with a detailed presentation of 4 phases from the third (adaptation) to the sixth (integration) of the Assessment-Decision-Adaptation-Production-Topical Experts-Integration-Training-Testing (ADAPT-ITT) framework. Methods: The adaptation phase followed a qualitative study design to explore symptoms of CMDs, facilitators, and barriers to conducting FB for people living with HIV on MMT in Vietnam, and patient, provider, and caretaker concerns about FB. In the production phase, we revised the original program manual and developed illustrated PST cases. In the topical expert and integration phases, 2 investigators (BNG and BWP) and 3 subject matter experts (RV, DC, and GML) reviewed the manual, with reviewer comments incorporated in the final, revised manual to be used in the training. The draft program will be used in the training and testing phases. Results: The study was methodologically aligned with the ADAPT-ITT goals as we chose a proven, effective program for adaptation. Insights from the adaptation phase addressed the who, where, when, and how of FB program implementation in the MMT clinics. The ADAPT-ITT framework guided the appropriate adaptation of the program manual while maintaining the core components of the PST of the original program throughout counseling techniques in all program sessions. The deliverable of this study was an adapted FB manual to be used for training and piloting to make a final program manual. Conclusions: This study successfully illustrated the process of operationalizing the ADAPT-ITT framework to adapt a mental health program in Vietnam. This study selected and culturally adapted an evidence-informed PST program to improve CMDs among people living with HIV on MMT in Vietnam. This adapted program has the potential to effectively address CMDs among people living with HIV on MMT in Vietnam.
MOESM1 of DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis
Creators: name: Fortezza, Marco La
name: Grigolon, Giovanna
name: Cosolo, Andrea
name: Pindyurin, Alexey
name: Breimann, Laura
name: Blum, Helmut
name: Steensel, Bas Van
name: Anne-Kathrin Classen
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Additional file 1. SupplementalÂ figures S1â S5.
Additional file 1 of Culture types and period impact gametophyte morphogenesis and sporophyte formation of eastern bracken
Creators: name: Jang, Bo-Kook
name: Cho, Ju-Sung
name: Kang, Shin-Ho
name: Lee, Cheol Hee
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Additional file 1: Table S1. Effect of gametophyte morphogenesis in accordance with culture type on sporophyte formation and growth of eastern bracken in ex vitro conditions. Figure S1. Experimental design diagram of ex vitro sporophyte propagation according to culture types and periods. zLiquid culture is more efficient for gametophyte proliferation than solid culture (shorter culture period and easier handling).
Unbinding Transition Induced by Osmotic Pressure in Relation to Unilamellar Vesicle Formation
Creators: name: Yamada, N. L.
name: Hishida, M.
name: Seto, H.
name: Tsumoto, K.
name: Yoshimura, T.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Small-angle X-ray scattering and phase-contrast microscopy experiments were performed to investigate the effect of the osmotic pressure on vesicle formation in a dioleoylphosphatidylcholine (DOPC)/water/NaI system. Multi-lamellar vesicles were formed when a pure lipid film was hydrated with an aqueous solution of NaI. On the other hand, uni-lamellar vesicles (ULVs) were formed when a lipid film mixed with an enough amount of NaI was hydrated. To confirm the effect of the osmotic pressure due to NaI, a free-energy calculation was performed. This result showed that the osmotic pressure induced an unbinding transition on the hydration process, which resulted in ULV formation.
title: ADCO, Cartulaire de Cîteaux pour les possessions d’Izeure (XVe siècle), Cart. 178 (11 H 80), 82 folios, f. 0016
Creators: name: de la Côte d'Or, Archives départementales
name: CG21/F.PETOT/2015
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les possessions d’Izeure (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 178 (11 H 80), 82 folios, f. 0016, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions d’Izeure (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 178 (11 H 80), 82 folios, f. 0016, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration
Creators: name: Pristerà, Alessandro
name: Blomeley, Craig
name: Lopes, Emanuel
name: Threlfell, Sarah
name: Merlini, Elisa
name: Burdakov, Denis
name: Cragg, Stephanie
name: Guillemot, François
name: Siew-Lan Ang
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Model organisms
subject: Imaging
subject: Gene Expression
subject: Genetics & Genomics
subject: Developmental Biology
subject: Microfabrication & Bioengineering
subject: Stem Cells
subject: Ecology,Evolution & Ethology
subject: Metabolism
subject: Computational & Systems Biology

description: Midbrain dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in controlling cognitive processes, reward mechanisms, and motor functions. The hormonal actions of insulin-like growth factor 1 (IGF-1) produced by the liver have been well described, but the role of neuronally derived IGF-1 remains largely unexplored. We discovered that dopamine neurons secrete IGF-1 from the cell bodies following depolarization, and that IGF-1 controls release of dopamine in the ventral midbrain. In addition, conditional deletion of dopamine neuron-derived IGF-1 in adult mice leads to decrease of dopamine content in the striatum and deficits in dopamine neuron firing and causes reduced spontaneous locomotion and impairments in explorative and learning behaviors. These data identify that dopamine neuron-derived IGF-1 acts as a regulator of dopamine neurons and regulates dopamine-mediated behaviors.
title: Minimizing Energy Use in Large Groundwater Supply Systems
Creators: name: Martin, Mikaela
Publisher: name: University of Massachusetts Amherst
Year: 2009
Subjects: subject: Environmental Engineering
subject: FOS: Environmental engineering

description: Two optimization formulations have been developed. The first formulation minimizes the energy required to pump water from an aquifer. This formulation is non- linear, requiring the use of quadratic terms in the objective function. The second formulation minimizes the maximum lift in an aquifer and is called the MINIMAX formulation. This formulation is linear and may be an acceptable substitution for the minimize energy formulation under conditions where there are small differences in initial lifts at the wells and where the demand is sufficient to require pumping at all wells such that the lifts at all wells are equal. The minimize energy and MINIMAX formulations were applied to four test models: a confined, homogeneous aquifer with two wells; a confined, homogeneous aquifer with 20 wells; a confined, heterogeneous aquifer with 20 wells; and an unconfined, homogeneous aquifer. The MINIMAX formulation produced the same results as the minimize energy formulation when the non-pumping lifts were the same. As the non-pumping lifts varied, the MINIMAX formulation deviated from the minimize energy formulation. A case study of the Lancaster subbasin of Antelope Valley, California, was used to further test the minimize energy and MINIMAX formulations. Two minimize energy formulations were examined, the first lifting water to the ground surface elevation at each well and the second lifting the water to a single reference elevation that took the value of the maximum ground surface elevation that was used in the first formulation. The MINIMAX formulation was applied to the case where the water was lifted to the reference elevation. The difference in total energy between the MINIMAX and minimize energy formulations was less than 10%, but the distribution of pumping among the wells varied greatly.
Electron Correlation Effects in Hyperfine Interactions in $^{45}$Sc and $^{89}$Y
Creators: name: Sahoo, Bijaya K.
name: Beier, Thomas
name: Das, B. P.
name: Chaudhuri, R. K.
name: Mukherjee, Debashis
Publisher: name: arXiv
Year: 2005
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The relativistic coupled-cluster theory has been employed to calculate the magnetic dipole and electric quadrupole hyperfine structure constants for the stable isotopes $^{45}$Sc and $^{89}$Y. The role of electron correlation is found to be very important. The trend exhibited by these effects is rather different from previously studied single valence atomic systems.
description: 5 pages, 1 figure, 3 tables
title: Périmètre d'irrigation des Abda - Doukkala. Carte des sols. Echelle 1/500 000
title: Périmètre d'irrigation des Abda - Doukkala. Carte des sols. Echelle 1/500 000
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Irrigation
subject: Périmètre irrigué
subject: Carte des sols

description: Echelle 1/500 000
description: Cartographie
description: BESM-carto_1954-63-p359_63-01
description: 359
description: 63
description: Bulletin économique et social du Maroc
description: Source: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Source: Bulletin économique et social du Maroc
description: Source: Bulletin économique et social du Maroc (BESM) > BESM (Cartographie)
description: Relation: https://cinumed.mmsh.univ-aix.fr/idurl/1/81725
description: Coverage: Maroc
description: Coverage: Doukkala
description: Coverage: Abda
description: Coverage: XXe siècle
description: Temporal: XXe siècle
description: Bibliographic citation: « Périmètre d'irrigation des Abda - Doukkala. Carte des sols. Echelle 1/500 000 », In Bulletin économique et social du Maroc (BESM), n° 63, 1954
description: Provenance: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Provenance: https://cinumed.mmsh.univ-aix.fr/
Orbital decomposition of CALIFA spiral galaxies
Creators: name: Zhu, Ling
name: Bosch, Remco van den
name: van de Ven, Glenn
name: Lyubenova, Mariya
name: Falcón-Barroso, Jesús
name: Meidt, Sharon E.
name: Martig, Marie
name: Shen, Juntai
name: Li, Zhao-Yu
name: Yildirim, Akin
name: Walcher, C. Jakob
name: Sanchez, Sebastian F.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Schwarzschild orbit-based dynamical models are widely used to uncover the internal dynamics of early-type galaxies and globular clusters. Here we present for the first time the Schwarzschild models of late-type galaxies: an SBb galaxy NGC 4210 and an S0 galaxy NGC 6278 from the CALIFA survey. The mass profiles within $2\,R_e$ are constrained well with $1σ$ statistical error of $\sim 10\%$. The luminous and dark mass can be disentangled with uncertainties of $\sim 20\%$ and $\sim 50\%$ respectively. From $R_e$ to $2\,R_e$, the dark matter fraction increases from $14\pm10\%$ to $18\pm10\%$ for NGC 4210 and from $15\pm10\%$ to $30\pm20\%$ for NGC 6278. The velocity anisotropy profiles of both $σ_r/σ_t$ and $σ_z/σ_R$ are well constrained. The inferred internal orbital distributions reveal clear substructures. The orbits are naturally separated into three components: a cold component with near circular orbits, a hot component with near radial orbits, and a warm component in between. The photometrically-identified exponential disks are predominantly made up of cold orbits only beyond $\sim 1\,R_e$, while they are constructed mainly with the warm orbits inside. Our dynamical hot components are concentrated in the inner regions, similar to the photometrically-identified bulges. The reliability of the results, especially the orbit distribution, are verified by applying the model to mock data.
description: accepted by MNRAS
The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens
Creators: name: Repana, Dimitra
name: Nulsen, Joel
name: Dressler, Lisa
name: Bortolomeazzi, Michele
name: Santhilata Kuppili Venkata
name: Tourna, Aikaterini
name: Yakovleva, Anna
name: Palmieri, Tommaso
name: Ciccarelli, Francesca D
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Genetics & Genomics
Genome Integrity & Repair
Gene Expression
Computational & Systems Biology

description: The Network of Cancer Genes (NCG) is a manually curated repository of 2372 genes whose somatic modifications have known or predicted cancer driver roles. These genes were collected from 275 publications, including two sources of known cancer genes and 273 cancer sequencing screens of more than 100 cancer types from 34,905 cancer donors and multiple primary sites. This represents a more than 1.5-fold content increase compared to the previous version. NCG also annotates properties of cancer genes, such as duplicability, evolutionary origin, RNA and protein expression, miRNA and protein interactions, and protein function and essentiality. NCG is accessible at http://ncg.kcl.ac.uk/ .
Global Aspects of p-Branes
Creators: name: Mickelsson, J.
name: Percacci, R.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We generalize to dimension $p>1$ the notion of string structure and discuss the related obstruction. We apply our results to a model of bosonic $p$-branes propagating on a principal $G$-bundle, coupled to a Yang--Mills field and an antisymmetric tensor field and in the presence of a Wess-Zumino term in the Lagrangian. We construct the quantization line bundle and discuss the action of background gauge transformations on wave functions.
description: 14 pages, plain TEX, SISSA 36/93/EP
Living With Chronic Pain: Recognising Grief And Strength Through Patient-Led Action Research
Creators: name: Clarke, Marian
Publisher: name: Royal College of Surgeons in Ireland
Year: 2022
Subjects: Clinical Psychology

description: Background: Many live with severe, disabling levels of chronic pain, accumulating pervasive life losses. Despite growing evidence that non-finite losses can lead to grief, scant literature connects chronic pain loss with expected grief trajectories.Problem: Little specific vocabulary exists to describe the experience of losses in living with chronic pain. Few therapeutic interventions create awareness or support those in pain recognising and understanding their response to these losses.Methods: Based in an Irish acute hospital Pain Management Programme, a patientinitiated collaborative project team created a narrative-based action research study, with focus groups and personal writing to explore themes of loss, grief and strength in living with chronic pain. Due to COVID-19 restrictions, the hospital-based clinical study has not yet progressed to implementation. Meanwhile, the patient-researcher used project methodology to analyse autoethnographic longitudinal data (email, WhatsApp).Process: Through reflexive thematic analysis, patterns of grief characteristics were recognised throughout the data. Themes include a battle to face living with loss, the ensuing grief and a need to tell about it.Results: Themes strongly correlate with grief models, grief assessments and the chronic pain literature, indicating that for the author, chronic pain has resulted in an ongoing experience of grief, including strength.Conclusion: Significant overlap of the data with grief models and chronic pain literature suggests that others may also experience grief and strength in response to loss in living with chronic pain, warranting further research in this area.
A proposal for a postgraduate education program in Tourism based on an integrated curriculum model
Creators: name: Vallejo Córdoba, José Víctor Manuel
name: Santiesteban-López, Norma Angélica
name: Pérez-Terrón, María Elena
name: Acle Mena, Ramón Sebastián
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390114
subject: Vocational education and training curriculum and pedagogy

description: The present research paper offers the criteria required by an education program for a new postgraduate degree in tourism, according to the requirements of the National Council for Science and Technology (CONACYT, for its abbreviation in Spanish) to be evaluated affiliate to the National Quality Postgraduate Program (PNPC, for its abbreviation in Spanish) within the Programs with Professional Orientation. The central purpose of the research is to compare the evaluation model of CONACYT’s PNPC (2015) professional orientation postgraduate programs with the curriculum model of Diaz-Barriga et al. (2013) to organize new postgraduate programs at public universities. An analysis of the elements that integrate the curriculum design is carried out. In this proposal of curriculum design, the elements that integrate it will be adapted to the area of tourism.
Additional file 1 of Investigation of the levels of circulating miR-29a, miR-122, sestrin 2 and inflammatory markers in obese children with/without type 2 diabetes: a case control study
Creators: name: Mohany, Khalid M.
name: Al Rugaie, Osamah
name: Al-Wutayd, Osama
name: Al-Nafeesah, Abdullah
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Additional file 1.
Role of an intermediate state in homogeneous nucleation
Creators: name: Monnai, Takaaki
name: Sugita, Ayumu
name: Nakamura, Katsuhiro
Publisher: name: arXiv
Year: 2006
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We explore the role of an intermediate state (phase) in homogeneous nucleation phenomenon by examining the decay process through a doubly-humped potential barrier. As a generic model we use the fourth- and sixth-order Landau potentials and analyze the Fokker-Planck equation for the one-dimensional thermal diffusion in the system characterized by a triple-well potential. In the low temperature case we apply the WKB method to the decay process and obtain the decay rate which is accurate for a wide range of depth and curvature of the middle well. In the case of a deep middle well, it reduces to a doubly-humped-barrier counterpart of the Kramers escape rate: the barrier height and the curvature of an initial well in the Kramers rate are replaced by the arithmetic mean of higher(or outer) and lower(or inner) partial barriers and the geometric mean of curvatures of the initial and intermediate wells, respectively. It seems to be a universal formula. In the case of a shallow-enough middle well, Kramers escape rate is alternatively evaluated within the standard framework of the mean-first-passage time problem, which certainly supports the WKB result. The criteria whether or not the existence of an intermediate state can enhance the decay rate are revealed.
description: 9pages, 11figures
Slégami, Open Access - Manuale d'uso per i ricercatori
Creators: name: Rosa, Matteo Di
name: Iasillo, Claudia
name: Giglia, Elena
name: Secinaro, Emanuela
name: Galimberti, Paola
name: Girard, Maria
name: Guttilla, Sara
name: Lorenzi, Luisa
name: Sala, Monica
name: MariaLaura Vignocchi
Publisher: name: Zenodo
Year: 2019
Subjects: open science, open access, open data

description: Il seguente documento nasce nell’ambito delle attività svolte dal Gruppo di Lavoro (GdL) APRE dedicato all’Open Science e si sviluppa come un manuale d’uso per i ricercatori sul tema Scienza Aperta e, nello specifico, sull’Open Access e l’Open Data.
 La sua redazione ha coinvolto attivamente tutti i membri del Gruppo di lavoro, composto da rappresentanti delle biblioteche e degli uffici di supporto alla ricerca di diverse università e centri di ricerca italiani (è possibile consultare la lista dei partecipanti nell’ultima pagina di questo documento).
 Il manuale è il prodotto finale di un lavoro che si è svolto in 3 fasi. Inizialmente, c’è stata una fase di raccolta delle domande più comuni poste dai ricercatori presso le strutture di supporto (siano esse Biblioteche o Grant Office) dei loro enti di appartenenza in materia di Open Access e Open Data. Nella fase successiva le domande sono state consolidate e aggregate in 6 clusters: (I) I falsi miti; (II) Considerazioni individuali; (III) Peer Review e Impact Factor, (IV) La proprietà intellettuale e il contratto con l’editore; (V) Quello che i ricercatori non sanno; (VI) Open Access e Progetti Europei.
 Durante la terza e ultima fase dello sviluppo del documento, alcuni membri, su base volontaria, hanno curato la redazione delle risposte, successivamente emendate in più riprese dall’intero gruppo di lavoro.
Variable Iron K-alpha Lines in Seyfert 1 Galaxies
Creators: name: Weaver, K. A.
name: Gelbord, J.
name: Yaqoob, T.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We find that variability of the iron K-alpha line is common in Seyfert 1 galaxies. Using data from the ASCA archive for objects that have been observed more than once during the mission, we study the time-averaged spectra from individual observations, thereby probing variability on timescales that range from days to years. Since the statistics of the data do not warrant searches for line variability in terms of a complex physical model, we use a a simple Gaussian to model the gross shape of the line, and then use the centroid energy, intensity and equivalent width as robust indicators of changes in the line profile. We find that ~70% of Seyfert 1s (ten out of fifteen) show variability in at least one of these parameters: the centroid energy, intensity, and equivalent width vary in six, four, and eight sources respectively. Due to the low S/N, limited sampling and time averaging, we consider these results to represent lower limits to the rate of incidence of variability. In most cases changes in the line do not appear to track changes in the continuum. In particular, we find no evidence for variability of the line intensity in NGC 4151, suggesting an origin in a region larger than the putative accretion disk, where most of the iron line has been thought to originate. Mkn 279 is investigated on short timescales. The time-averaged effective line energy is 6.5 keV in the galaxy rest frame. As the continuum flux increases by 20% in a few hours, the Fe K line responds with the effective line energy increasing by 0.22 keV (~10,500 km s^-1). Problems with the ASCA and Rosat calibration that affect simultaneous spectral fits are discussed in an appendix.
description: 26 pages, 30 figures, accepted for publication in the Astrophysical Journal
Dilaton, Antisymmetric Tensor and Gauge Fields in String Effective Theories at the One--loop Level
Creators: name: Mayr, P.
name: Stieberger, S.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the dependence of the gauge couplings on the dilaton field in string effective theories at the one--loop level. First we resolve the discrepancies between statements based on symmetry considerations and explicit calculations in string effective theories on this subject. A calculation of the relevant one--loop scattering amplitudes in string theory gives us further information and allows us to derive the exact form of the corresponding effective Lagrangian. In particular there is no dilaton dependent one--loop correction to the holomorphic $f$--function arising from massive string modes in the loop. In addition we address the coupling of the antisymmetric tensor field to the gauge bosons at one--loop. While the string S--matrix elements are not reproduced using the usual supersymmetric Lagrangian with the chiral superfield representation for the dilaton field, the analogue Lagrangian with the dilaton in a linear multiplet naturally gives the correct answer.
description: Latex, 20 pages, 3 figures (available upon request), MPI--Ph/93--19
Low loss QKD optical scheme for fast polarization encoding
Creators: name: Duplinskiy, A.
name: Ustimchik, V.
name: Kanapin, A.
name: Kurochkin, V.
name: Kurochkin, Y.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a new optical scheme for BB84 protocol quantum key distribution (QKD). The proposed setup consists of a compact all-fiber polarization encoding optical scheme based on LiNbO3 phase modulators, single laser source and two single-photon detectors. Optical scheme consists of standard telecommunication components and is suitable for both fiber and free-space quantum communication channels. Low losses (~2dB) in Bob's device increase both the key generation rate and distance limit. A new technique for solving polarization mode dispersion (PMD) issue in LiNbO3 is implemented, allowing two crystals to neutralize the effect of each other. Several proof-of-concept experiments have been conducted at 10 MHz repetition frequency over 50 km of standard optical fiber under laboratory conditions and over 30 km of urban fiber with high losses (13dB), which is a link within a QKD network. To achieve this, calibration algorithms have been developed, allowing the system to work autonomously and making it promising for practical applications.
description: 11 pages, 7 figures
Effect of Quality of Caregiver-Adolescent Relationship on Sexual Debut, Transactional Sex, and on Age-Disparate Relationships Among Young Women in Rural South Africa Enrolled in HPTN 068
Creators: name: Stoner, M.
name: Gómez-Olivé, X.
name: Pence, B.
name: Shangase, N.
name: Pettifor, A.
name: Edwards, J.
name: Hussong, A.
name: Kahn, K.
name: Aiello, A.
Publisher: name: Lippincott Williams and Wilkins
Year: 2022

description: Background:Adolescent girls and young women (AGYW) remain burdened by the HIV epidemic. Positive caregiver-child relationships are associated with safe sexual behaviors in young people; yet, this literature often highlights the role of parent-child communication and parental monitoring, neglecting the importance of emotional relationships between a caregiver and adolescent.Setting:We used longitudinal data from HIV Prevention Trial Network 068 - conducted among 2533 AGYW (13-20 years) over a period of 5 years in Agincourt, South Africa.Method:Kaplan-Meier and Cox models were used to estimate the effect of quality of caregiver-adolescent relationships (caring and closeness) on sexual debut, and log-binomial models with generalized estimating equations were used to examine the relationship between our exposures and transactional sex and age-disparate relationships.Results:Sexual debut was delayed among those who reported high levels of caregiver caring [hazard ratio: 0.80, 95% confidence interval (CI): 0.69 to 0.93] and caregiver closeness (hazard ratio: 0.80, 95% CI: 0.68 to 0.95). AGYW who reported high quality caregiver-adolescent relationships had a lower risk of transactional sex [caring: risk ratio (RR): 0.67, 95% CI: 0.58 to 0.78; closeness: RR: 0.58; 95% CI: 0.50 to 0.67]. Similarly, those with high-quality caregiver-adolescent relationships were less likely to be in an age-disparate relationship (caring: RR: 0.68, 95% CI: 0.58 to 0.79; closeness: RR: 0.77, 95% CI: 0.66 to 0.90).Conclusions:Findings indicate high-quality caregiver-adolescent relationships are associated with delayed sexual debut, a lower risk of transactional sex, and having an older partner. Family-centered interventions are needed to improve relationships between AGYW and caregivers.
MOESM1 of DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis
Creators: name: Fortezza, Marco La
name: Grigolon, Giovanna
name: Cosolo, Andrea
name: Pinduyrin, Alexey
name: Breimann, Laura
name: Blum, Helmut
name: Steensel, Bas Van
name: Anne-Kathrin Classen
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Additional file 1. SupplementalÂ figures S1â S5.
Temperature dependence of the resistance of metallic nanowires (diameter $\geq$ 15 nm): Applicability of Bloch-Grüneisen theorem
Creators: name: Bid, Aveek
name: Bora, Achyut
name: Raychaudhuri, A. K.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We have measured the resistances (and resistivities) of Ag and Cu nanowires of diameters ranging from 15nm to 200nm in the temperature range 4.2K-300K with the specific aim to assess the applicability of the Bloch-Grüneisen formula for electron phonon resistivity in these nanowires. The wires were grown within polymeric templates by electrodeposition. We find that in all the samples the resistance reaches a residual value at T=4.2K and the temperature dependence of resistance can be fitted to the Bloch-Grüneisen formula in the entire temperature range with a well defined transport Debye temperature ($Θ_{R}$). The value of Debye temperature obtained from the fits lie within 8% of the bulk value for Ag wires of diameter 15nm while for Cu nanowires of the same diameter the Debye temperature is significantly lesser than the bulk value. The electron-phonon coupling constants (measured by $α_{el-ph}$ or $α_{R}$) in the nanowires were found to have the same value as that of the bulk. The resistivities of the wires were seen to increase as the wire diameter was decreased. This increase in the resistivity of the wires may be attributed to surface scattering of conduction electrons. The specularity p was estimated to be about 0.5. The observed results allow us to obtain the resistivities exactly from the resistance and gives us a method of obtaining the exact numbers of wires within the measured array (grown within the template).
description: 9 pages, 10 figures
Spectroscopic inversions of the Ca ii 8542 Å line in a C-class solar flare
Creators: name: Kuridze, D.
name: Henriques, V.
name: Mathioudakis, M.
name: Koza, J.
name: Zaqarashvili, T. V.
name: Rybák, J.
name: Hanslmeier, A.
name: Keenan, F. P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We study the C8.4 class solar flare SOL2016-05-14T11:34 UT using high-resolution spectral imaging in the Ca ii 8542 Å line obtained with the CRISP imaging spectropolarimeter on the Swedish 1-m Solar Telescope. Spectroscopic inversions of the Ca ii 8542 Å line using the non-LTE code NICOLE are used to investigate the evolution of the temperature and velocity structure in the flare chromosphere. A comparison of the temperature stratification in flaring and non-flaring areas reveals strong footpoint heating during the flare peak in the lower atmosphere. The temperature of the flaring footpoints between continuum optical depth at 500~nm, $\mathrm{log~τ_{500}~\approx -2.5~and~ -3.5}$ is $\mathrm{\sim5-6.5~kK}$, close to the flare peak, reducing gradually to $\mathrm{\sim5~kK}$. The temperature in the middle and upper chromosphere, between $\mathrm{log~τ_{500} \approx - 3.5~and~- 5.5}$, is estimated to be $\mathrm{\sim6.5 - 20~kK}$, decreasing to pre-flare temperatures, $\mathrm{\sim5 - 10~kK}$, after approximately 15 minutes. However, the temperature stratification of the non-flaring areas is unchanged. The inverted velocity fields show that the flaring chromosphere is dominated by weak downflowing condensations at the Ca ii 8542 Å formation height.
description: 9 pages, 6 figures, accepted in ApJ
The cost-effectiveness of depression screening for the general adult population
Creators: name: Swann, J.
name: Gaynes, B.N.
name: Pence, B.W.
name: Yildirim, M.
name: Keskinocak, P.
Publisher: name: Elsevier B.V.
Year: 2022

description: Background: Depression is a treatable disease, and untreated depression can lead to serious health complications and decrease the quality of life. Therefore, prevention, early identification, and treatment efforts are essential. Screening has an essential role in preventive medicine in the general population. Ideally, screening tools detect patients early enough to manage the disease and reduce symptoms. We aimed to determine the cost-effectiveness of routine screening schedules. Methods: We used a discrete-time nonstationary Markov model to simulate the progression of depression. We used Monte Carlo techniques to simulate the stochastic model for 20 years or during the lifetime of individuals. Baseline and screening scenario models with screening frequencies of annual, 2-year, and 5-year strategies were compared based on incremental cost-effectiveness ratios (ICER). Monte Carlo (MC) simulation and one-way sensitivity analysis were conducted to manage uncertainties. Results: In the general population, all screening strategies were cost-effective compared to the baseline. However, male and female populations differed based on cost over quality-adjusted life years (QALY). Females had lower ICERs, and annual screening had the highest ICER for females, with 11,134$/QALY gained. In contrast, males had around three times higher ICER, with annual screening costs of 34,065$/QALY gained. Limitations: We assumed that the screening frequency was not changing at any time during the screening scenario. In our calculations, false-positive cases were not taking into account. Conclusions: Considering the high lifetime prevalence and recurrence rates of depression, detection and prevention efforts can be one critical cornerstone to support required care. Our analysis combined the expected benefits and costs of screening and assessed the effectiveness of screening scenarios. We conclude that routine screening is cost-effective for all age groups of females and young, middle-aged males.