cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
P. Herc. 1057: detailed study
Creators: name: Marichal, Robert
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015

description: vue 100
description: A list of 6 latin papyri (P.Herc. 153, 1057, 1491, 1624, 1665, 76) under the category: 'Capital baroque cursive. Mayuscule élégante et baroque', with the drawing of the letters on the left of the sheet; most details are about P.Herc. 1057; 2 micro-photographic negatives of P.Herc. 1057 attached to this sheet; notes on the writing angle of P.Herc. 1057. - A detailed papyrological description of P.Herc. 1057 (cornici and pezzi, puntuation, critical and lectional signs, abbreviations, accents) is followed by annotations on the personal names occuring in the papyrus, with sources and bibliography; all these pages are numbered (red ink; upper right corner) from 1 to 13. - Sheets enclosed in one folder (entitled 'Les Pisons') containing a detailed study on the Roman family of Pisones: family tree and biographical details on some of the members; except for the family tree, all pages have the indication "Propriétaires de la Villa dei Papiri“ (also in a shortened form). - Papyrological description of P.Herc. 1057 (cornici, punctuation, lectional and critical signs, abbreviation, ecc.: draft of the pages which open the folder?), and transcription; each page is marked by the very same sign written with a red ink in the upper right corner, and many items are cossed out with red ink. Several sheets of the same format containing detailed annotations on the occurrences of puntuation, accent, and various signs are crossed out with red ink. Drawings of the fragments placed in each frame; addings and remarks written with different ink (dark pink and light green); additional notes and the indication 'Vu 54' are written in the upper right corner.Typed transcriptions of frr. 10 and 11. Pictures of each described and transcribed fragment with the date on the back. The cover page of the folder contains the title: 'P.1057. Discours au Senat'
description: Source: 4MAR_10_2_5-19.3
description: Relation: 4MAR_2_5-13.1, 4MAR_2_5-19.2,4MAR_2_5-19.4, 4MAR_2_5-19.5, 4MAR_2_5-19.7, 4MAR_2_5-19.8, 4MAR_42_4-3, 4MAR_42_4-6, 4MAR_42_4-7
description: created: n.d., 1957
Additional file 1 of Comparing the contents of patient-reported outcome measures for fatigue: EORTC CAT Core, EORTC QLQ-C30, EORTC QLQ-FA12, FACIT, PRO-CTCAE, PROMIS, Brief Fatigue Inventory, Multidimensional Fatigue Inventory, and Piper Fatigue Scale
Creators: name: Rothmund, Maria
name: Pilz, Micha J.
name: Egeter, Nathalie
name: Lidington, Emma
name: Piccinin, Claire
name: Arraras, Juan I.
name: Groenvold, Mogens
name: Holzner, Bernhard
name: van Leeuwen, Marieke
name: Petersen, Morten Aa.
name: Ramage, John
name: Schmidt, Heike
name: Young, Teresa
name: Giesinger, Johannes M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 1.
A20 as a Potential New Tool in Predicting Recurrence and Patient’s Survival in Oral Squamous Cell Carcinoma
Creators: name: Spoerl, Steffen
name: Erber, Ramona
name: Gerken, Michael
name: Taxis, Juergen
name: Ludwig, Nils
name: Nieberle, Felix
name: Biermann, Niklas
name: Geppert, Carol Immanuel
name: Ettl, Tobias
name: Hartmann, Arndt
name: Beckhove, Philipp
name: Reichert, Torsten E.
name: Spanier, Gerrit
name: Spoerl, Silvia
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: oral squamous cell carcinoma; OSCC; A20; tissue microarray; TNFAIP3
subject: 610 Medizin

description: A20, known as a potent inhibitor of NF-κB signaling, has been characterized in numerous clinical as well as preclinical studies. Recently, especially in various malignant diseases, the prognostic and therapeutic relevance of A20 was investigated. In oral squamous cell carcinoma (OSCC) however, the characterization of A20 is uncharted territory. We analyzed a tissue microarray (TMA) of 229 surgically-treated OSCC patients (2003–2013). Immunohistochemical (IHC) stainings were performed for A20 and CD3; additionally, standard haematoxylin-eosin staining was applied. IHC findings were correlated with a comprehensive dataset, comprising clinical and pathohistological information. A20 expression was analyzed in tumor cells as well as in tumor infiltrating lymphocytes (TILs) and correlated with the overall survival (OS) and recurrence-free survival (RFS) using uni- and multivariable Cox regression. The median follow-up time was 10.9 years and the A20 expression was significantly decreased in CD3+ TILs compared to mucosa-infiltrating lymphocytes (MILs). In the Kaplan–Meier analyses, higher A20 expression in TILs was correlated with better OS (p = 0.017) and RFS (p = 0.020). In the multivariable survival analysis, A20 overexpression correlated with improved OS (HR: 0.582; 95% CI 0.388–0.873, p = 0.009) and RFS (HR 0.605; 95% CI 0.411–0.889, p = 0.011). Our results indicate a novel prognostic role for A20 in OSCC. Due to its elevated expression in TILs, further research is highly desirable, which therefore could offer new therapeutic opportunities for patients suffering from OSCC.
Opposing MMP-9 Expression in Mesenchymal Stromal Cells and Head and Neck Tumor Cells after Direct 2D and 3D Co-Culture
Creators: name: Waltera, Anna
name: Schulz, Daniela
name: Schaefer, Nicole
name: Stoeckl, Sabine
name: Pion, Eric
name: Haerteis, Silke
name: Reichert, Torsten E.
name: Ettl, Tobias
name: Bauer, Richard J.
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: HNSCC; head and neck cancer; BMSC; bone marrow-derived stromal cells; angiogenesis; MMP; matrix metalloproteinase; CAM; chorioallantoic membrane; in ovo, 2D; 3D
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor cell-derived signals, such as inflammatory cytokines and growth factors. As a result, the inflammatory tumor microenvironment may lead to the recruitment of BMSCs. Whether BMSCs in the tumor environment are more likely to promote tumor growth or tumor suppression is still controversial. In our experiments, direct 3D co-culture of BMSCs with tumor cells from the head and neck region (HNSCC) results in strong expression and secretion of MMP-9. The observed MMP-9 secretion mainly originates from BMSCs, leading to increased invasiveness. In addition to our in vitro data, we show in vivo data based on the chorioallantoic membrane (CAM) model. Our results demonstrate that MMP-9 induces hemorrhage and increased perfusion in BMSC/HNSCC co-culture. While we had previously outlined that MMP-9 expression and secretion originate from BMSCs, our data showed a strong downregulation of MMP-9 promoter activity in HNSCC cells upon direct contact with BMSCs using the luciferase activity assay. Interestingly, the 2D and 3D models of direct co-culture suggest different drivers for the downregulation of MMP-9 promoter activity. Whereas the 3D model depicts a BMSC-dependent downregulation, the 2D model shows cell density-dependent downregulation. In summary, our data suggest that the direct interaction of HNSCC cells and BMSCs promotes tumor progression by significantly facilitating angiogenesis via MMP-9 expression. On the other hand, data from 3D and 2D co-culture models indicate opposing regulation of the MMP-9 promoter in tumor cells once stromal cells are involved.
Correspondence (1910-1992)
Creators: name: Corbier, Mireille
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015

description: vue 24
description: "Letters to Marichal dated between 1991 and 1992 on various subjects . -  Letter (with envelop) from  Mireille Corbier (date: 03-01-1991) asking Marichal elucidations on the evolution of Latin writing. - Letter (with envelop) from Michel Lejeune (date: 11-01-1991) on the reading of a graffito found at Chátillon-sur-Seiche; the image of the graffito is attached to the letter. – Letter by Xavier RInchel (date: 15-02-1991) asking information concerning the passage from the format of the roll to one of the codex (mention of R. Marichal, Du volumen au codex, in H.-J. Martin, J Vezin éds. Mise en page et mise en texte du livre et du manuscrit, Paris 1990, pp. 45-54).- Letters (the first is a copy) from Elisabeth Lalou (date: 19-02-1991, 16-05-1991) concerning the preparation and publication of the article 'Les tablettes à écrire dans le monde Romain', in éd. E. Lalou Les Tablettes à écrire de l'Antiquité à l'époque moderne , Brepols 1992 (= Bibliologia 12), pp. 165-18; a third sheet is attached to the others containing a summary (not written by Marichal) of the requests made by E. Lalou. - Greeting letter from Jaqueline Bonneval (02-03-1991), a pupil of Marichal. - Letter from Fiorella Romano (Biblioteca Nazionale di Napoli; date: 24-04-1991) concerning Marichal's request of sending in France P.Herc. Paris 2 (containing the mention of Vergil) for an exibition organized by the Bibliothèque de l'Institut de France). - Letter from Marcello Gigante (date: 22-04-1991) on the P. Herc. Paris 2 (mentioning Vergil) and on the work made by Marichal on the Latin writing in Herculaneum papyri; mention of to CE XI and XII. - Letter from Marcello Gigante (date: 30-04-1991) on the opening of P. Herc. Paris 1 and P. Herc. Paris 2 by K. Kleve (1985-1989). - Application form for buying P. Salat, Verborum Ratio. Exemple d'études statistiques portant sur le vocabulaire latin, Publications de la Faculté des Lettres de l'Université Blaise-Pascal, 350 (1991). - Letter from Denis Muzerelle (Secretary of the Comité International de Paleographie Latin; date 17-09-1991) announcing the death of Bernhard Bischiff. - Letter from Ivan Gorby (date 25-09-1991) asking Marichal to become a member of the 'Comité d'Honneur' of the School St. Louis; a depliant of the School is attached to the letter. - Greeting Message from Valeria and Marcello Gigante  (23-07-1991).- Letter from F. Feury-Hue (11-10-1991) on inscriptions of Sidrac. - Report (21-01-1992) of the meeting of the 'Comité de l'association amicale des anciens élèves de l'école Saint-Aspais de Melun', held the 21st of December 1991. - Letter (inside the evnvelop) dated at 06-01-1992 with greetings to Robert and his wife, and with indication of a possible meeting. -  2 invitations (for Robert Marichal and his wife) to the meeting organized by the Institut de France on 11-02-1992."
description: Source: 4MAR_28_6_2-4
description: created: 1991-1992
Akodon (Akodon) paranaensis Christoff, Fagundes, Sbalqueiro, Mattevi, and Yonenaga-Yassuda 2000
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Akodon
Akodon paranaensis

description: Akodon (Akodon) paranaensis Christoff, Fagundes, Sbalqueiro, Mattevi, and Yonenaga-Yassuda 2000
Akodon (Akodon) paranaensis Christoff, Fagundes, Sbalqueiro, Mattevi, and Yonenaga-Yassuda 2000, J. Mammal., 81: 844.
Type Locality: Brazil, Paraná State, Piraquara, Estação Ecologica Canguiri.
Vernacular Names: Parana Akodont.
Distribution: NE Argentina (Misiones Prov.), SE Brazil (Paraná and Rio Grande do Sul).
Discussion: Subgenus Akodon. Populations assigned to this species had been formerly identified as A. serrensis (e.g., Liascovich and Reig, 1989), but karyotypic and morphometric separation from that form clarified by Christoff et al. (2000). Similar in size to members of the A. mollis species group (sensu Hershkovitz, 1990 c), but Christoff et al. (2000) left the assignment of A. paranaensis as species group indeterminate pending additional study of its relationship. Also see remarks under A. mystax and involved discussion by Pardiñas et al. (2003 a) on the tenuous basis for segregating paranaensis and reigi; resolution is needed.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1098, DOI: 10.5281/zenodo.7316535
Chorioallantoic Membrane Assay at the Cross-Roads of Adipose-Tissue-Derived Stem Cell Research
Creators: name: Oliinyk, Dmytro
name: Eigenberger, Andreas
name: Felthaus, Oliver
name: Haerteis, Silke
name: Prantl, Lukas
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: adipose-derived stem cells; mesenchymal stem cells; chorioallantoic membrane; CAM assay; wound healing; tissue regeneration; tissue engineering; scaffolds; biocompatibility
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: With a history of more than 100 years of different applications in various scientific fields, the chicken chorioallantoic membrane (CAM) assay has proven itself to be an exceptional scientific model that meets the requirements of the replacement, reduction, and refinement principle (3R principle). As one of three extraembryonic avian membranes, the CAM is responsible for fetal respiration, metabolism, and protection. The model provides a unique constellation of immunological, vascular, and extracellular properties while being affordable and reliable at the same time. It can be utilized for research purposes in cancer biology, angiogenesis, virology, and toxicology and has recently been used for biochemistry, pharmaceutical research, and stem cell biology. Stem cells and, in particular, mesenchymal stem cells derived from adipose tissue (ADSCs) are emerging subjects for novel therapeutic strategies in the fields of tissue regeneration and personalized medicine. Because of their easy accessibility, differentiation profile, immunomodulatory properties, and cytokine repertoire, ADSCs have already been established for different preclinical applications in the files mentioned above. In this review, we aim to highlight and identify some of the cross-sections for the potential utilization of the CAM model for ADSC studies with a focus on wound healing and tissue engineering, as well as oncological research, e.g., sarcomas. Hereby, the focus lies on the combination of existing evidence and experience of such intersections with a potential utilization of the CAM model for further research on ADSCs.
Akodon (Akodon) pervalens Thomas 1925
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Akodon
Akodon pervalens

description: Akodon (Akodon) pervalens Thomas 1925
Akodon (Akodon) pervalens Thomas 1925, Ann. Mag. Nat. Hist., ser. 9, 15: 579.
Type Locality: Bolivia, Tarija Dept., Caraparí, 1000 m.
Vernacular Names: Tarija Akodont.
Distribution: SC Bolivia, 900-2100 m (presumably into N Argentina).
Discussion: Subgenus Akodon. Status and relationship variously recognized: named as a subspecies of A. sylvanus by Thomas (1925; as followed by Musser and Carleton, 1993); reallocated to a subspecies of A. varius by Cabrera (1961); retained as a nominal species similar to A. cursor by Myers (1989); placed as a synonym of A. serrensis by Hershkovitz (1990 c). As dryly noted by Anderson (1997), who also listed pervalens as species, the want of unanimity in its treatment underlines the need for taxonomic resolution.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1098, DOI: 10.5281/zenodo.7316535
Study and develop stabilization treatment for multi-materials and galvanic corrosion assessment - Deliverable D3.2
Creators: name: Guilminot Elodie
name: Escobar Claros Cesar
Publisher: name: Zenodo
Year: 2023
Subjects: PROCRAFT
Cultural Heritage
Aircraft
Archaeology
WWII
Aluminium Alloy
Duralumin
Conservation
Aviation Archaeology

description: The purpose of this deliverable is to report on the work carried out in Task 3.2 of WP3 (Curative conservation treatments), concerning the study and development of treatments for multi-materials (Al alloys associated with steel).
Akodon (Akodon) reigi González, Langguth, and Oliveira 1998
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Akodon
Akodon reigi

description: Akodon (Akodon) reigi González, Langguth, and Oliveira 1998
Akodon (Akodon) reigi González, Langguth, and Oliveira 1998, Comun. Zool. Mus. Hist. Nat. Montevideo, 12 (191): 2.
Type Locality: Uruguay, Lavalleja Dept., Paso Averias; 33º60′S, 54º40′W.
Vernacular Names: Reig's Akodont.
Distribution: Gallery forests of E Uruguay and extreme S Brazil (Rio Grande do Sul).
Discussion: Subgenus Akodon, A. cursor species group sensu Rieger et al. (1995). Principally contrasted to A. cursor and A. serrensis; see remarks by González et al. (1998) on karyotype (2n = 44) and misattributed reports of this new species as A. serrensis. Status and distributional limits with regard to A. mystax and especially A. paranaensis deserve careful review (see those accounts and discussion by Pardiñas et al., 2003 a).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1098, DOI: 10.5281/zenodo.7316535
title: Activité du port de Saint-Malo – 1756 – Cherbourg
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: produits manufacturés
subject: armes et munitions
subject: minerais et métaux

description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1756 avec le port "Cherbourg"
description: Marchandises arrivées à Saint-Malo : poudre ; balles ; fer ; papier
description: Catégories de marchandises arrivées à Saint-Malo : produits manufacturés ; armes et munitions ; minerais et métaux
description: Coverage: Petit cabotage
description: Bibliographic citation: CHARLOU, Auguste. Les Activités du port de Saint-Malo en 1756. DES : Histoire : Rennes : 1967 (Bibliothèque François-Lebrun, MH 1046)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
title: The Use of Complex Versus Normal Modes in Structural Model Improvement
Creators: name: Lin, Chih
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1983

description: In the past, normal modes approximation to complex modes was
employed by most researchers or users in the process of identification
or modification of structural systems. This is true, of course for
simple structures with no or proportional damping. For complex
structures with nonproportional damping, even level of which is small,
it will be shown that applying this approximation is inadequate. Use of
complex modes instead of approximated normal modes is Justified.

An algorithm is presented that computes a set of normal modes from
the corresponding measured complex modes. The computed normal modes are
then used in the Berman's technique to improve an analytical approximated
mass matrix. A numerical experiment is conducted to validate the
proposed theory. Results show that the use of computed normal modes in
the correction procedure produces better improvements in the mass matrix
than the use of approximated ones if complex modes exist in the measured
range.
Additional file 1 of Sexual dimorphism in the effects of maternal adipose tissue growth hormone receptor deficiency on offspring metabolic health
Creators: name: Ran, Liyuan
name: Wang, Xiaoshuang
name: Ma, Rui
name: Wang, Haoan
name: Wu, Yingjie
name: Yu, Zichao
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Computational Biology

description: Supplementary Material 1
Expression of pH-Sensitive TRPC4 in Common Skin Tumors
Creators: name: Kurz, Bernadett
name: Michael, Hannah Philine
name: Förch, Antonia
name: Wallner, Susanne
name: Zeman, Florian
name: Decking, Sonja-Maria
name: Ugele, Ines
name: Hintschich, Constantin
name: Haubner, Frank
name: Ettl, Tobias
name: Renner, Kathrin
name: Brochhausen, Christoph
name: Schreml, Stephan
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: TRPC4; skin tumors; melanoma; squamous cell carcinoma; basal cell carcinoma
subject: 610 Medizin

description: TRPCs (transient receptor potential classical or cation channels) play a crucial role in tumor biology, especially in the Ca2+ homeostasis in cancer cells. TRPC4 is a pH-sensitive member of this family of proteins. As solid tumors exhibit an inversed pH-gradient with lowered extracellular and increased intracellular pH, both contributing to tumor progression, TRPC4 might be a signaling molecule in the altered tumor microenvironment. This is the first study to investigate the expression profiles of TRPC4 in common skin cancers such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC), malignant melanoma (MM) and nevus cell nevi (NCN). We found that all SCCs, NCNs, and MMs show positive TRPC4-expression, while BCCs do only in about half of the analyzed samples. These data render TRPC4 an immunohistochemical marker to distinguish SCC and BCC, and this also gives rise to future studies investigating the role of TRPC4 in tumor progression, and especially metastasis as BCCs very rarely spread and are mostly negative for TRPC4.
Additional file 2 of Sexual dimorphism in the effects of maternal adipose tissue growth hormone receptor deficiency on offspring metabolic health
Creators: name: Ran, Liyuan
name: Wang, Xiaoshuang
name: Ma, Rui
name: Wang, Haoan
name: Wu, Yingjie
name: Yu, Zichao
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Computational Biology

description: Supplementary Material 1
title: Activité du port de Saint-Malo – 1763 – Granville
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: minerais et métaux
subject: armes et munitions
subject: épices et condiments
subject: textiles
subject: produits chimiques et médicinaux
subject: matériaux de construction
subject: produits de la mer
subject: poissons
subject: produits manufacturés
subject: produits agroalimentaires
subject: alcool
subject: produits combustibles
subject: personnes
subject: produits exotiques et ultramarins

description: Marchandises au départ de Saint-Malo : mâtures ; sardines ; résine ; morues ; filain ; funain ; pain ; biscuits ; goudron ; eau de vie ; savon ; brai ; graisse ; planches ; passagers ; sucre ; fer ; sardines ; sel ; canons
description: Catégories de marchandises au départ de Saint-Malo : matériaux de construction ; produits de la mer ; poissons ; matériaux de construction ; produits manufacturés ; produits agroalimentaires ; alcool ; produits combustibles ; personnes ; produits exotiques et ultramarins ; minerais et métaux ; armes et munitions ; épices et condiments
description: Marchandises arrivées à Saint-Malo : morues ; paniers ; morues ; harengs ; passagers ; lin ; toiles ; pierre à chaux ; cidre ; clous ; meubles
description: Catégories de marchandises arrivées à Saint-Malo : produits de la mer ; poissons ; produits manufacturés ; personnes ; textiles ; produits chimiques et médicinaux ; produits agroalimentaires ; alcool
description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1763 avec le port "Granville"
description: Coverage: Petit cabotage
description: Bibliographic citation: CHEREL, Huguette. L'Activité du port de Saint-Malo en 1763. DES : Histoire : Rennes : 1967 (Bibliothèque François-Lebrun, MH 1052)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Pilot study of a smartphone-based tinnitus therapy using structured counseling and sound therapy: A multiple-baseline design with ecological momentary assessment
Creators: name: Engelke, Milena
name: Simões, Jorge
name: Vogel, Carsten
name: Schoisswohl, Stefan
name: Schecklmann, Martin
name: Wölflick, Stella
name: Pryss, Rüdiger
name: Probst, Thomas
name: Langguth, Berthold
name: Schlee, Winfried
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: 610 Medizin

description: Tinnitus affects a considerable part of the population and develops into a severe disorder in some sufferers. App-based interventions are able to provide low-threshold, cost-effective, and location-independent care for tinnitus patients. Therefore, we developed a smartphone app combining structured counseling with sound therapy and conducted a pilot study to evaluate treatment compliance and symptom improvement (trial registration: DRKS00030007). Outcome variables were Ecological Momentary Assessment (EMA) measured tinnitus distress and loudness and Tinnitus Handicap Inventory (THI) at baseline and final visit. A multiple-baseline design with a baseline phase (only EMA) followed by an intervention phase (EMA and intervention) was applied. 21 patients with chronic tinnitus (≥ 6 months) were included. Overall compliance differed between modules (EMA usage: 79% of days, structured counseling: 72%, sound therapy: 32%). The THI score improved from baseline to final visit indicating a large effect (Cohens d = 1.1). Tinnitus distress and loudness did not improve significantly from baseline phase to the end of intervention phase. However, 5 of 14 (36%) improved clinically meaningful in tinnitus distress (ΔDistress ≥ 10) and 13 of 18 (72%) in THI score (ΔTHI ≥ 7). The positive relationship between tinnitus distress and loudness weakened over the course of the study. A trend but no level effect for tinnitus distress could be demonstrated by a mixed effect model. The improvement in THI was strongly associated with the improvement scores in EMA of tinnitus distress (r = -0.75; 0.86). These results indicate that app-based structured counseling combined with sound therapy is feasible, has an impact on tinnitus symptoms and reduces distress for several patients. In addition, our data suggest that EMA could be used as a measurement tool to detect changes in tinnitus symptoms in clinical trials as has already been shown in other areas of mental health research.
Factores de posicionamiento en el SEO académico
Creators: name: Alcaraz Martínez, Rubén
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 461099
subject: Library and information studies not elsewhere classified

description: es: Factores de posicionamiento en el SEO académico (ASEO) clasificados por tipología (directo / indirecto), momento (prepublicación / postpublicación) y actor involucrado (autor / editor / bibliotecario). Para cada factor se incluye una descripción y referencias bibliográficas. Datos relacionados con el artículo: Alcaraz-Martínez, Rubén (2024). Identificación de factores de posicionamiento en el SEO académico (ASEO) a través de una scoping review. BiD, 53. https://doi.org/10.1344/bid2024.53.02en: Academic SEO ranking factors (ASEO) classified by typology (direct / indirect), moment (pre-publication / post-publication) and actor involved (author / publisher / librarian). For each factor a description and bibliographical references are included. Data related to the article: Alcaraz-Martínez, Rubén (2024). Identification of positioning factors in academic SEO (ASEO) through a scoping review. BiD, 53. https://doi.org/10.1344/bid2024.53.02
Akodon (Akodon) sanctipaulensis Hershkovitz 1990
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Akodon
Akodon sanctipaulensis

description: Akodon (Akodon) sanctipaulensis Hershkovitz 1990
Akodon (Akodon) sanctipaulensis Hershkovitz 1990, Fieldiana Zool., N. S., 57: 23.
Type Locality: Brazil, São Paulo, Primeiro Morro.
Vernacular Names: Sao Paulo Akodont.
Distribution: Serra do Mar, SE Brazil.
Conservation: IUCN – Lower Risk (nt).
Discussion: Subgenus Akodon, A. boliviensis species group (Hershkovitz, 1990 c). Morphological separation from A. cursor and A. serrensis amplified by Christoff et al. (2000).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1098, DOI: 10.5281/zenodo.7316535
Correspondence from Knut Kleve and various annotation on the Latin Herculaneum papyri
Creators: name: Kleve, Knut
name: Marichal, Robert
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015

description: vue 42
description: Letter from Knut Kleve (15-05-1991) asking a collaboration on the Latin Herculaneum papyri, with photographs of fragments of P.Herc. 21, P.Herc. s.n. cass. CXIV pap. I, P.Herc. Paris 1, P.Herc. Paris 2, and some drawings (published in "CErc" 19 (1989), 5-27 and "CErc" 20 (1990), 5-16. - Pages from the report of the French Academy of Sciences on the opening of the Herculaneum Papyri preserved in Paris (P.Herc. Paris). - Two lists of all the Latin Herculaneum papyri (63 in total) and various annotation: += 'oui dossier'; ++= 'recopié'; + with pink ink =xxx?. Each number is accompanied by the indication of the typology of writing; in one of the two list (the older?) additional pieces of information (mostly measures) are added with red ink. - Several sheets mostly of the same format (but with different prints) containing various kind of annotations: structure and order of the pieces of information to be given in presenting a papyrus from Herculaneum; list of bibliographical abbreviations; necessary pieces of information to be written in a catalogue; bibliographical references on various topic; annotations (sources and bibliography) about eminent Roman personalities.
description: Source: 4MAR_10_2_5-19.1
description: Relation: 4MAR_2_5-3, 4MAR_2_5-4, 4MAR_2_5-10, 4MAR_2_5-11, 4MAR_2_5-12, 4MAR_2_5-13, 4MAR_2_5-14, 4MAR_2_5-15, 4MAR_2_5-16, 4MAR_2_5-17, 4MAR_2_5-18
description: created: n.d., 1991
Thysanoplusia
Creators: name: Ronkay, Laszlo
name: Behounek, Gottfried
name: Müller, Günter C.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Noctuidae
Thysanoplusia

description: * Thysanoplusia (s.l.) distalagma (Hampson, 1913)
(Fig. 19)
Material examined. Bako Gazer woreda, Jinka. 1400m. VIII.2011. Leg. Kravchenko V. Literature. Hampson 1913.
General distribution pattern. The species is known from the eastern part of equatorial Africa (Kenya, Tanzania, and Uganda) and South Africa.
Distribution in Ethiopia. Southern Ethiopia (Omo region). Rare.
description: Published as part of Ronkay, Laszlo, Behounek, Gottfried & Müller, Günter C., 2015, PLusiinae (Excl. Abrostolini) (Lepidoptera: Noctuidae) of Ethiopia. A faunistical survey with biogeographical comments, pp. 235-251 in Zootaxa 4013 (2) on pages 240-241, DOI: 10.11646/zootaxa.4013.2.5, http://zenodo.org/record/234589
Vitamin D Deficiency in Orthopedic Patients in Different Latitudes—First Study Comparing German and Greek Populations
Creators: name: Mamilos, Andreas
name: Matzaroglou, Charalambos
name: Maier, Gerrit S.
name: Zawy Alsofy, Samer
name: Drees, Philipp
name: Kafchitsas, Konstantinos
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: vitamin D; hypovitaminosis D; sunlight exposure; Greek–German population
subject: 610 Medizin

description: Vitamin D plays a pivotal role in calcium metabolism and bone mineralization. Sufficient vitamin D levels are important for the health and functionality of the musculoskeletal system. Hypovitaminosis D is a phenomenon affecting orthopedic patients worldwide. This study researched whether most orthopedic patients in two different cities of different countries had hypovitaminosis D, whether there was a correlation between sunshine hours and vitamin D serum levels, and whether hours of sunshine alone were enough to achieve vitamin D sufficiency among orthopedic patients regardless of their activities. The vitamin D serum levels of 500 orthopedic patients in Regensburg and 500 in Patras were assessed, in addition to their medical histories. The mean sunshine hours throughout the year were also calculated. Both the German and Greek groups showed hypovitaminosis D. Older patients were more affected. Although there were more hours of sunshine in Greece, Greek orthopedic patients also showed hypovitaminosis D. Hypovitaminosis D affects orthopedic patients independent of their latitude. Supplementation of vitamin D may be considered among orthopedic patients to achieve sufficient levels in serum. Sufficient vitamin D levels may be helpful for the treatment of orthopedic patients, reduce the negative effects of operations or postoperational settings.
Macrophages: From Simple Phagocyte to an Integrative Regulatory Cell for Inflammation and Tissue Regeneration—A Review of the Literature
Creators: name: Mamilos, Andreas
name: Winter, Lina
name: Schmitt, Volker H.
name: Barsch, Friedrich
name: Grevenstein, David
name: Wagner, Willi
name: Babel, Maximilian
name: Keller, Karsten
name: Schmitt, Christine
name: Gürtler, Florian
name: Schreml, Stephan
name: Niedermair, Tanja
name: Rupp, Markus
name: Alt, Volker
name: Brochhausen, Christoph
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: macrophage; plasticity; monocytes; inflammation; tissue regeneration; biomaterials; M1-macrophages; M2-macrophages
subject: 610 Medizin

description: The understanding of macrophages and their pathophysiological role has dramatically changed within the last decades. Macrophages represent a very interesting cell type with regard to biomaterial-based tissue engineering and regeneration. In this context, macrophages play a crucial role in the biocompatibility and degradation of implanted biomaterials. Furthermore, a better understanding of the functionality of macrophages opens perspectives for potential guidance and modulation to turn inflammation into regeneration. Such knowledge may help to improve not only the biocompatibility of scaffold materials but also the integration, maturation, and preservation of scaffold-cell constructs or induce regeneration. Nowadays, macrophages are classified into two subpopulations, the classically activated macrophages (M1 macrophages) with pro-inflammatory properties and the alternatively activated macrophages (M2 macrophages) with anti-inflammatory properties. The present narrative review gives an overview of the different functions of macrophages and summarizes the recent state of knowledge regarding different types of macrophages and their functions, with special emphasis on tissue engineering and tissue regeneration.
Nebria (Barbonebriola) Huber & Schmidt, 2017, subgen. nov
Creators: name: Huber, Charles
name: Schmidt, Joachim
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Carabidae
Nebria

description: Key to species of Barbonebriola subgen. nov
1 Midlateral and basolateral setae of pronotum absent. Lateral groove of pronotum narrow. Far Western Nepal: Api Himal. ....... N. tenuisulcata sp. nov.
– One midlateral setae of pronotum present, basolateral seta absent. ..... 2
2 Striae of elytra on disc only faintly punctate or impunctate. Basal margin of pronotum straight, not incised. West Nepal, Kanjiroba Himal: Kagmara La. .............................................................................. N. kagmara sp. nov.
– Striae of elytra on disc strongly and densely punctate. Basal margin of pronotum distinctly incised. .................................................................... 3
3 Antennal scape short, ovoid. Lateral groove of pronotum narrow. India, Himachal Pradesh: Rohtang pass. ..................... N. ganeshi LEDOUx, 1984
– Antennal scape long, slender, subcylindrical, longer than the eye's diameter. Lateral groove of the pronotum wide. ........................................ 4
4 Elytra ovoid, laterally regularly rounded. Shoulder less pronounced. Far Western Nepal: Saipal Himal. .................................. N. rubostipes sp. nov.
– Elytra elliptic to subovoid, lateral margin subparallel. Shoulder pronounced. ................................................................................................. 5
5 Pronotum flattened, wide, ratio width/length =1.45. Kashmir Himalaya of India and Pakistan. ........................................ N. barbata ANDREWES, 1929
– Pronotum domed, slender, ratio width/length = 1.25. India, Uttarakhand: Badrinath. ............................................ N. restricta LEDOUx & ROUx, 2005
description: Published as part of Huber, Charles & Schmidt, Joachim, 2017, Notes on the Nebria subgenus Epinebriola K. DANIEL, 1904 with the description of Barbonebriola subgen. nov. and 13 new species from the Himalaya-Tibet orogen (Coleoptera, Carabidae, Nebriini), pp. 1-85 in Contributions to Natural History 36 on pages 78-79, DOI: 10.5169/seals-787049, http://zenodo.org/record/6285683
Additional file 3 of Immune alterations and overexpression of CTCF in endometrial carcinoma: insights from molecular subtyping
Creators: name: Wei, Caiping
name: Chen, Guowei
name: Chen, Kun
name: Fang, Shuang
name: He, Hongying
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3.
Quality Attributes and Shelf Life of Goat´s Milk Kefir
Creators: name: Ayed, Mariem
Publisher: name: Zenodo
Year: 2024
Subjects: Pasteurized goat milk
Kefir grains
Fermented beverages
Physicochemical
Microbiological
Sensory
Properties
Response surface

description: Thesis submitted to the School of Agriculture of the Polytechnic Institute of Bragança, Portugal, to obtain the Degree of Master in Food Quality and Safety, under the scope of the Double Diploma with Université Libre de Tunis, Tunisia.
Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model
Creators: name: Babl, Nathalie
name: Hofbauer, Joshua
name: Matos, Carina
name: Voll, Florian
name: Menevse, Ayse Nur
name: Rechenmacher, Michael
name: Mair, Ruth
name: Beckhove, Philipp
name: Herr, Wolfgang
name: Siska, Peter J.
name: Renner, Kathrin
name: Kreutz, Marina
name: Schnell, Annette
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: cholesterol, LDL (low-density lipoprotein), immunotherapy, PD-1, reactive oxygen species, CD154 (CD40L), central memory (T) CM, spheroid model
subject: 610 Medizin

description: Introduction: 
The discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows sufficient response to therapy. Hence, there is a need for identifying new checkpoints and predictive biomarkers with the objective of overcoming immune escape and resistance to treatment. Having been associated with both, treatment response and failure, LDL seems to be a double-edged sword in anti-PD1 immunotherapy. Being embedded into complex metabolic conditions, the impact of LDL on distinct immune cells has not been sufficiently addressed. Revealing the effects of LDL on T cell performance in tumor immunity may enable individual treatment adjustments in order to enhance the response to routinely administered immunotherapies in different patient populations. The object of this work was to investigate the effect of LDL on T cell activation and tumor immunity in-vitro.
Methods: 
Experiments were performed with different LDL dosages (LDLlow = 50 μg/ml and LDLhigh = 200 μg/ml) referring to medium control. T cell phenotype, cytokines and metabolism were analyzed. The functional relevance of our findings was studied in a HCT116 spheroid model in the context of anti-PD-1 blockade.
Results: 
The key points of our findings showed that LDLhigh skewed the CD4+ T cell subset into a central memory-like phenotype, enhanced the expression of the co-stimulatory marker CD154 (CD40L) and significantly reduced secretion of IL-10. The exhaustion markers PD-1 and LAG-3 were downregulated on both T cell subsets and phenotypical changes were associated with a balanced T cell metabolism, in particular with a significant decrease of reactive oxygen species (ROS). T cell transfer into a HCT116 spheroid model resulted in a significant reduction of the spheroid viability in presence of an anti-PD-1 antibody combined with LDLhigh.
Discussion: 
Further research needs to be conducted to fully understand the impact of LDL on T cells in tumor immunity and moreover, to also unravel LDL effects on other lymphocytes and myeloid cells for improving anti-PD-1 immunotherapy. The reason for improved response might be a resilient, less exhausted phenotype with balanced ROS levels.
title: Lettre n°661 de Paul d'Estournelles de Constant à Nicholas Murray Butler (1 mai 1920)
title: Letter number 661 from Paul d'Estournelles de Constant to Nicholas Murray Butler (May 1, 1920)
Creators: name: d'Estournelles de Constant, Paul
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Pacifisme
Guerre mondiale (1914-1918)

description: Source: Archives de la Sarthe – France
Body Composition as a Comorbidity-Independent Predictor of Survival following Nephroureterectomy for Urothelial Cancer of the Upper Urinary Tract
Creators: name: Pickl, Christoph
name: Engelmann, Simon
name: Girtner, Florian
name: Gužvić, Miodrag
name: van Rhijn, Bas W. G.
name: Hartmann, Valerie
name: Holbach, Sonja
name: Kälble, Sebastian
name: Haas, Maximilian
name: Rosenhammer, Bernd
name: Breyer, Johannes
name: Burger, Maximilian
name: Mayr, Roman
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: sarcopenia; fat distribution; prognosis; skeletal muscle; urothelial neoplasm; transitional cell carcinoma
subject: 610 Medizin

description: Radical nephroureterectomy (NUE) is the gold standard treatment for high-risk urothelial cancer of the upper urinary tract (UTUC). Besides sarcopenia and frailty, fat distribution is moving increasingly into focus. Components of body composition were assessed in patients undergoing NUE due to UTUC. The study cohort included 142 patients. By using CT-based measurements, the skeletal muscle index (SMI), subcutaneous adipose tissue index (SATI), and visceral adipose tissue index (VATI) were measured at the height of the third lumbar vertebra. Overall survival (OS) and cancer-specific survival (CSS) were estimated using univariable und multivariable Cox regression models. The prevalence of sarcopenia in the study population (n = 142) was 37%. OS and CSS were significantly reduced in sarcopenic patients. In the multivariable cox regression analysis, including age, ACE-27, T-stage, R-stage, LVI and necrosis, sarcopenia remained a significant risk factor of OS (HR, 1.77; 95% CI 1.02–3.07; p = 0.042) and CSS (HR, 2.17; 95% CI 1.18–3.99; p = 0.012). High visceral adipose tissue seems to be protective, although not statistically significant. Sarcopenia is a comorbidity-independent risk factor in patients who underwent NUE due to UTUC. Visceral fat represents a potentially protective factor. These results suggest that specific factors of body composition can be used for better risk stratification.
Additional file 6 of Immune alterations and overexpression of CTCF in endometrial carcinoma: insights from molecular subtyping
Creators: name: Wei, Caiping
name: Chen, Guowei
name: Chen, Kun
name: Fang, Shuang
name: He, Hongying
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 6.
title: Activité du port de Saint-Malo – 1717 – Saint-Brieuc
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: produits manufacturés
subject: produits de la mer
subject: poissons
subject: alcool
subject: matériaux de construction
subject: minerais et métaux
subject: produits agroalimentaires
subject: céréales
subject: produits combustibles
subject: cuirs, peaux et laines

description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1717 avec le port "Saint-Brieuc"
description: Marchandises au départ de Saint-Malo : savon ; morue ; moulage ; bière ; fer ; moules ; plâtre
description: Catégories de marchandises au départ de Saint-Malo : produits manufacturés ; produits de la mer ; poissons ; alcool ; matériaux de construction ; minerais et métaux ; produits de la mer
description: Marchandises arrivées à Saint-Malo : miel ; froment ; brai ; bois à feu ; sabots ; peaux de veau ; planches d'orme ; laine ; fer ; douvelles ; chandelles ; planches
description: Catégories de marchandises arrivées à Saint-Malo : produits agroalimentaires ; céréales ; matériaux de construction ; produits combustibles ; produits manufacturés ; cuirs, peaux et laines
description: Coverage: Petit cabotage
description: Bibliographic citation: RUELLAND, Jean-Marc. Le Commerce malouin durant les années 1717-1718. DES : Histoire : Rennes, s.d. (Bibliothèque François-Lebrun, MH 1022)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Conversion of Hemicellulose into Furfural Using Solid Acid Catalysts in γ-Valerolactone
Creators: name: Gurbuz, Elif
name: Gallo, Jean Marcel
name: Martin Alonso, David
name: Wettstein, Sthephanie
name: Wee, Lim
name: Dumesic, James
Publisher: name: Wiley / Zenodo
Year: 2012

description: The hemicellulose fraction of lignocellulose can be converted into furfural in high yields (80 %) using solid acid catalysts (H-mordenite) in a monophasic system with γ-valerolactone (GVL) as the solvent. Furfural degradation reactions are decreased significantly when the water concentration in GVL is minimized, thus resulting in high furfural yields.