cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Quantifying White-Tailed Deer Density and Its Impact on Agricultural Systems
Creators: name: Matthews, Jonathan A.
Publisher: name: University of Kentucky Libraries
Year: 2019

description: White-tailed deer (Odocoileus virginianus) commonly consume row crops, with yield losses often attributed to their browsing. Deer density and field morphology may predict yield losses within local areas. We sought to 1) determine the effects of deer browsing on corn and soybean yields and investigate if deer density or field morphology correlated to yield loss in western Kentucky, and 2) compare pellet-based distance sampling to game camera surveys to determine if a distance sampling technique could accurately estimate deer density during the growing season. Overall, deer reduced corn and soybean yields on one-half of surveyed properties. Deer density did not influence yield losses in either crop; however, field morphology correlated with soybean yield losses. Pellet-based distance sampling provided statistically similar estimates as our game camera survey technique; however, at the individual farm level distance sampling estimates proved unreliable. Inaccurate model parameter (i.e., defecation rates) and inability to detect pellet groups in dense vegetation complicated the reliability of distance sampling models. Overall, yield losses from deer occur in western Kentucky and may be a localized event. Finally, game camera surveys should be used over pellet-based distance sampling during the growing season until detection issues and inaccurate model parameters are solved.
description: Copyright © Jonathan A. Matthews 2019
description: Funding information: Funding was provided by the Kentucky Soybean Board and National Corn Growers Association.
Efficiently Cooled Stellar Wind Bubbles in Turbulent Clouds II. Validation of Theory with Hydrodynamic Simulations
Creators: name: Lancaster, Lachlan
name: Ostriker, Eve C.
name: Kim, Jeong-Gyu
name: Kim, Chang-Goo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In a companion paper, we develop a theory for the evolution of stellar wind driven bubbles in dense, turbulent clouds. This theory proposes that turbulent mixing at a fractal bubble-shell interface leads to highly efficient cooling, in which the vast majority of the input wind energy is radiated away. This energy loss renders the majority of the bubble evolution momentum-driven rather than energy-driven, with expansion velocities and pressures orders of magnitude lower than in the classical Weaver77 solution. In this paper, we validate our theory with three-dimensional, hydrodynamic simulations. We show that extreme cooling is not only possible, but is generic to star formation in turbulent clouds over more than three orders of magnitude in density. We quantify the few free parameters in our theory, and show that the momentum exceeds the wind input rate by only a factor ~ 1.2-4. We verify that the bubble/cloud interface is a fractal with dimension ~ 2.5-2.7. The measured turbulent amplitude (v_t ~ 200-400 km/s) in the hot gas near the interface is shown to be consistent with theoretical requirements for turbulent diffusion to efficiently mix and radiate away most of the wind energy. The fraction of energy remaining after cooling is only 1-Θ~ 0.1-0.01, decreasing with time, explaining observations that indicate low hot-gas content and weak dynamical effects of stellar winds.
description: Accepted for publication in ApJ, 36 pages, 25 figures, but short summary and conclusion. Comments welcome
Herriott-Cavity-Assisted Closed-Loop Xe Isotope Comagnetometer
Creators: name: Hao, Chuanpeng
name: Yu, QianQian
name: Yuan, Chunqi
name: Liu, Siqi
name: Sheng, Dong
Publisher: name: arXiv
Year: 2021
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We present in this paper a Herriott-cavity-assisted closed-loop Xe isotope gas comagnetometer. In this system, $^{129}$Xe and $^{131}$Xe atoms are pumped and probed by polarized Rb atoms, and continuously driven by oscillating magnetic fields, whose frequencies are kept on resonance by phase-locked loops (PLLs). Different from other schemes, we use a Herriott cavity to improve the Rb magnetometer sensitivity instead of the parametric modulation method, and this passive method is aimed to improve the system stability while maintaining the sensitivity. This system has demonstrated an angle random walk (ARW) of 0.06 $^\circ$/h$^{1/2}$, and a bias instability of 0.2 $^\circ$/h (0.15 $μ$Hz) with a bandwidth of 1.5 Hz. By adding a closed-loop Rb isotope comagnetometer, we can extend this system to dual simultaneously working comagnetometers sharing the same cell. This extended system has wide applications in precision measurements, where we can simultaneously and independently measure the coupling of anomalous fields with proton spin and neutron spin.
description: Accepted by Physical Review A
Random Quantum Operations
Creators: name: Bruzda, Wojciech
name: Cappellini, Valerio
name: Sommers, Hans-Jürgen
name: Życzkowski, Karol
Publisher: name: arXiv
Year: 2008
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We define a natural ensemble of trace preserving, completely positive quantum maps and present algorithms to generate them at random. Spectral properties of the superoperator Phi associated with a given quantum map are investigated and a quantum analogue of the Frobenius-Perron theorem is proved. We derive a general formula for the density of eigenvalues of Phi and show the connection with the Ginibre ensemble of real non-symmetric random matrices. Numerical investigations of the spectral gap imply that a generic state of the system iterated several times by a fixed generic map converges exponentially to an invariant state.
Cross-beam energy transfer saturation by ion trapping-induced detuning
Creators: name: Nguyen, K. L.
name: Yin, L.
name: Albright, B. J.
name: Hansen, A. M.
name: Froula, D. H.
name: Turnbull, D.
name: Follett, R. K.
name: Palastro, J. P.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The performance of direct-drive inertial confinement fusion implosions relies critically on the coupling of laser energy to the target plasma. Cross-beam energy transfer (CBET), the resonant exchange of energy between intersecting laser beams mediated by ponderomotively driven ion-acoustic waves (IAW), inhibits this coupling by scattering light into unwanted directions. The variety of beam intersection angles and varying plasma conditions in an implosion results in IAWs with a range of phase velocities. Here we show that CBET saturates through a resonance detuning that depends on the IAW phase velocity and that results from trapping-induced modifications to the ion distribution functions. For smaller phase velocities, the modifications to the distribution functions can rapidly thermalize in the presence of mid-Z ions, leading to a blueshift in the resonant frequency. For larger phase velocities, the modifications can persist, leading to a redshift in the resonant frequency. Ultimately, these results may reveal pathways towards CBET mitigation and inform reduced models for radiation hydrodynamics codes to improve their predictive capability.
Structure of Quasiparticles and Their Fusion Algebra in Fractional Quantum Hall States
Creators: name: Barkeshli, Maissam
name: Wen, Xiao-Gang
Publisher: name: arXiv
Year: 2008
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: It was recently discovered that fractional quantum Hall (FQH) states can be classified by the way ground state wave functions go to zero when electrons are brought close together. Quasiparticles in the FQH states can be classified in a similar way, by the pattern of zeros that result when electrons are brought close to the quasiparticles. In this paper we combine the pattern-of-zero approach and the conformal-field-theory (CFT) approach to calculate the topological properties of quasiparticles. We discuss how the quasiparticles in FQH states naturally form representations of a magnetic translation algebra, with members of a representation differing from each other by Abelian quasiparticles. We find that this structure dramatically simplifies topological properties of the quasiparticles, such as their fusion rules, charges, and scaling dimensions, and has consequences for the ground state degeneracy of FQH states on higher genus surfaces. We find constraints on the pattern of zeros of quasiparticles that can fuse together, which allow us to obtain the fusion rules of quasiparticles from their pattern of zeros, at least in the case of the (generalized and composite) parafermion states. We also calculate from CFT the number of quasiparticle types in the generalized and composite parafermion states, which confirm the result obtained previously through a completely different approach.
description: v2: 16 pages. New section added and some substantial changes to previous version
Finite-size scaling of directed percolation in the steady state
Creators: name: Janssen, Hans-Karl
name: Lubeck, Sven
name: Stenull, Olaf
Publisher: name: arXiv
Year: 2007
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Recently, considerable progress has been made in understanding finite-size scaling in equilibrium systems. Here, we study finite-size scaling in non-equilibrium systems at the instance of directed percolation (DP), which has become the paradigm of non-equilibrium phase transitions into absorbing states, above, at and below the upper critical dimension. We investigate the finite-size scaling behavior of DP analytically and numerically by considering its steady state generated by a homogeneous constant external source on a d-dimensional hypercube of finite edge length L with periodic boundary conditions near the bulk critical point. In particular, we study the order parameter and its higher moments using renormalized field theory. We derive finite-size scaling forms of the moments in a one-loop calculation. Moreover, we introduce and calculate a ratio of the order parameter moments that plays a similar role in the analysis of finite size scaling in absorbing nonequilibrium processes as the famous Binder cumulant in equilibrium systems and that, in particular, provides a new signature of the DP universality class. To complement our analytical work, we perform Monte Carlo simulations which confirm our analytical results.
description: 21 pages, 6 figures
Towards a community-endorsed data steward profession description for life science research - Poster: KSA
Creators: name: Scholtens, Salome
name: Anbeek, Petronella
name: Böhmer, Jasmin
name: Brullemans-Spansier, Mirjam
name: Geest, Marije Van Der
name: Jetten, Mijke
name: Staiger, Christine
name: Slouwerhof, Inge
name: Gelder, Celia W G Van
Publisher: name: Zenodo
Year: 2019
Subjects: Data Management
Data Stewardship
Skill building
Competencies
Life Sciences

description: Poster presented at ELIXIR EXCELERATE All Hands meeting 2019 displaying a selection of knowledge, skills and abilities (KSAs) for Data Stewards in the Life Sciences. Special focus on responsibility areas, tasks, KSAs and learning objective matrix of Data Steward Type A, which is concerned with policies and procedures: a collection of responsibilities and activities related to FAIR data, compliance to scientific integrity, and institutional research data management policy.
description: This project is funded by the ZonMw Personalised Medicine Programme under Dossier number: 80-84600-98-3007. The project period is Aug 2018 - July 2019. Additional funding will be provided by UMCG, UMCU, Radboud University Nijmegen, Radboudumc and DTL/ELIXIR-Netherlands.
Predication of topological states in the allotropes of group-IV elements
Creators: name: Zhong, Chengyong
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Three-dimensional topological insulators have been studied for approximately fifteen years, but those made from group-IV elements, especially Ge and Sn, seem particularly attractive owing to their nontoxicity, sizable intrinsic spin-orbit coupling (SOC) strength and natural compatibility with the current semiconductor industry. However, group-IV elemental TIs have rarely been reported, except for the low temperature phase of alpha-Sn under strain. Here, based on first-principles calculations, we propose new allotropes of Ge and Sn, named T5-Ge(Sn), as desirable TIs. These new allotropes are also highly anisotropic Dirac semimetals if the SOC is turned off. To the best of our knowledge, T5-Ge(Sn) are the first 3D allotropes of Ge(Sn) that possess topological states in their equilibrium state at room temperature. Additionally, their isostructures of C and Si are metastable indirect and direct semiconductors. Our work not only reveals two promising TIs, but more profoundly, we justify the advantages of group-IV elements as topological quantum materials (TQMs) for fundamental research and potential practical applications, and thus reveal a new direction in the search for desirable TQMs.
description: 15 pages,6 figures,has been accepted by Frontiers of Physics
Pyrrolizine-3-ones: Synthesis and evaluation of photophysical properties
Creators: name: Tasgin, Dilek Isik
name: Bayraktar, Irem
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: We describe a synthetic approach for pyrrolizine-3-one derivatives and their photophysical properties. These compounds are prepared by a series of reactions employing the substituted pyrroles in one-pot, two-step oxidation, and intramolecular cyclization processes. The photophysical properties of the synthesized compounds were studied by using UV–Vis and fluorescence spectroscopy in different solvents. Maximum absorbance peaks were observed around 306–416 nm and maximum fluorescence emission around 603–614 nm and 465–498 nm for pyrrolyl and N-methyl pyrrolyl substituents, respectively. The introduction of a pyrrolyl substituent had a significant impact on the Stokes shifts (192–206 nm) and quantum yield values ranged from 0.002 to 0.046.
A simple and convenient synthesis of labeled 9-hydroxy[13C6]phenanthrene as internal standard for mass spectrometry quantification of a key phenanthrene metabolite in human urines
Creators: name: Sancéau, Jean-Yves
name: Gaudreau, Éric
name: Maltais, René
name: Poirier, Donald
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Hematology
subject: Plant Biology

description: A simple and convenient synthesis of 9-hydroxy[13C6]phenanthrene has been developed from one-ring labeled [13C6]phenanthrene in three steps, involving a copper-ethyl acetate catalyzed “Ullmann-type” reaction. The mild conditions of this nucleophilic aromatic substitution are particularly advantageous in the case of expensive labeled material. Stable-labeled 9-hydroxy[13C6]phenanthrene has proven to be an ideal [M + 6]isotopomer for use as an internal standard for quantification of OH-polycyclic aromatic hydrocarbons by gas chromatography with tandem mass spectrometry (GC-MS/MS) in human urines.
La misura della sostenibilità alla scala provinciale attraverso la valutazione ambientale strategica. Una proposta di metodo.
Creators: name: Calenda, Cristina
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2008

description: L’impellente necessità di tradurre nella pratica le disposizioni della Direttiva Comunitaria n. 42/2001 unita ai poco consolidati riferimenti metodologici esistenti nel settore hanno rappresentato due punti di partenza per sviluppare questo progetto di ricerca, che si propone come finalità la costruzione di una proposta di metodo per l’esecuzione della valutazione ambientale strategica di un piano territoriale di coordinamento provinciale.
La finalità è stata articolata nei seguenti obiettivi, ciascuno dei quali ha contraddistinto una fase di articolazione del presente lavoro:
1.la ricostruzione del dibattito scientifico sulle valutazioni di sostenibilità di piani e programmi e la definizione del contesto normativo esistente in materia a livello internazionale, nazionale e regionale;
2.la conoscenza delle applicazioni di VAS più significative e l’individuazione dei principali approcci metodologici adottati nel settore;
3.la messa a punto di una proposta metodologica per l’esecuzione della valutazione ambientale strategica da applicare ad un piano territoriale di coordinamento provinciale, fondata sulla misura della disponibilità del territorio a subire trasformazioni;
4.l’applicazione e la verifica del metodo proposto.
Design, Synthesis and Biological Evaluation of Aryl Benzimidazole-Pyridones as Cytotoxic Agents
Creators: name: Sabita, G.
name: Syed, Tasqeeruddin
name: Savitha, R.
name: Divya, K.
name: Somaiah, Nalla
name: Bhaskar, K.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology

description: A new library of Aryl Benzimidazole-Pyridones (9a–j) has been synthesized, their structures were determined by 1HNMR,13CNMR and mass spectral data. Further, these compounds explored for their anticancer application on four human cancer cell lines such as human prostate cancer cell line (PC3), lung cancer (A549), breast cancer (MCF-7) and human ovarian cancer (A2780) by employing MTT assay and results were compared with known anticancer agent asetoposide. All these compounds displayed remarkable cytotoxic activity. Among them, five compounds 9a, 9b, 9c, 9h and 9i displayed more potent activity. All compounds exhibited a discerning cytotoxic effect on cancer cells while not affecting normal Vero cells (IC50 = >22 µM), so providing justification for the strategic design approach employed in the development of a targeted anticancer drug.
title: Transport Legislation Amendment Bill 2023: Bill Brief
Creators: name: Tonkin, Angus
name: Wright, Annie
Publisher: name: Parliamentary Library and Information Service (Vic)
Year: 2023

description: The Transport Legislation Amendment Bill 2023 introduces a number of amendments across Victoria’s transport framework. The most heavily publicised provision is the introduction of a closed-track trial to investigate how medicinal cannabis users can drive safely. This Bill Brief examines the amendments relating specifically to the road safety trial.
Approaching the Basis Set Limit in Gaussian-Orbital-Based Periodic Calculations with Transferability: Performance of Pure Density Functionals for Simple Semiconductors
Creators: name: Lee, Joonho
name: Feng, Xintian
name: Cunha, Leonardo A.
name: Gonthier, Jerome F.
name: Epifanovsky, Evgeny
name: Head-Gordon, Martin
Publisher: name: arXiv
Year: 2021
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Simulating solids with quantum chemistry methods and Gaussian-type orbitals (GTOs) has been gaining popularity. Nonetheless, there are few systematic studies that assess the basis set incompleteness error (BSIE) in these GTO-based simulations over a variety of solids. In this work, we report a GTO-based implementation for solids, and apply it to address the basis set convergence issue. We employ a simple strategy to generate large uncontracted (unc) GTO basis sets, that we call the unc-def2-GTH sets. These basis sets exhibit systematic improvement towards the basis set limit as well as good transferability based on application to a total of 43 simple semiconductors. Most notably, we found the BSIE of unc-def2-QZVP-GTH to be smaller than 0.7 m$E_h$ per atom in total energies and 20 meV in band gaps for all systems considered here. Using unc-def2-QZVP-GTH, we report band gap benchmarks of a combinatorially designed meta generalized gradient functional (mGGA), B97M-rV, and show that B97M-rV performs similarly (a root-mean-square-deviation (RMSD) of 1.18 eV) to other modern mGGA functionals, M06-L (1.26 eV), MN15-L (1.29 eV), and SCAN (1.20 eV). This represents a clear improvement over older pure functionals such as LDA (1.71 eV) and PBE (1.49 eV) though all these mGGAs are still far from being quantitatively accurate. We also provide several cautionary notes on the use of our uncontracted bases and on future research on GTO basis set development for solids.
Uplink Coverage in Heterogeneous mmWave Cellular Networks with Clustered Users
Creators: name: Wang, Xueyuan
name: Gursoy, M. Cenk
Publisher: name: arXiv
Year: 2021
Subjects: subject: Information Theory (cs.IT)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: A K-tier heterogeneous mmWave uplink cellular network with clustered user equipments (UEs) is considered in this paper. In particular, UEs are assumed to be clustered around small-cell base stations (BSs) according to a Gaussian distribution, leading to the Thomas cluster process based modeling. Specific and practical line-of-sight (LOS) and non-line-of-sight (NLOS) models are adopted with different parameters for different tiers. The probability density functions (PDFs) and complementary cumulative distribution functions (CCDFs) of different distances from UEs to BSs are characterized. Coupled association strategy and largest long-term averaged biased received power criterion are considered, and general expressions for association probabilities are provided. Following the identification of the association probabilities, the Laplace transforms of the inter-cell interference and the intra-cluster interference are characterized. Using tools from stochastic geometry, general expressions of the SINR coverage probability are provided. As extensions, fractional power control is incorporated into the analysis, tractable closed-form expressions are provided for special cases, and average ergodic spectral efficiency is analyzed. Via numerical and simulation results, analytical characterizations are confirmed and the impact of key system and network parameters on the performance is identified.
description: To be published in IEEE Access
Discovery of coherent millisecond X-ray pulsations in Aql X-1
Creators: name: Casella, P.
name: Altamirano, D.
name: Patruno, A.
name: Wijnands, R.
name: van der Klis, M.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the discovery of an episode of coherent millisecond X-ray pulsation in the neutron star low-mass X-ray binary Aql X-1. The episode lasts for slightly more than 150 seconds, during which the pulse frequency is consistent with being constant. No X-ray burst or other evidence of thermonuclear burning activity is seen in correspondence with the pulsation, which can thus be identified as occurring in the persistent emission. The pulsation frequency is 550.27 Hz, very close (0.5 Hz higher) to the maximum reported frequency from burst oscillations in this source. Hence we identify this frequency with the neutron star spin frequency. The pulsed fraction is strongly energy dependent, ranging from <1% (3-5 keV) to >10% (16-30 keV). We discuss possible physical interpretations and their consequences for our understanding of the lack of pulsation in most neutron star low-mass X-ray binaries. If interpreted as accretion-powered pulsation, Aql X-1 might play a key role in understanding the differences between pulsating and non-pulsating sources.
description: 5 pages, 3 figures, accepted by ApJ Letters after minor revisions. Slightly extended discussion. One author added. Uses emulateapj.cls
Allosteric Communications between Domains Modulate the Activity of Matrix Metalloprotease-1
Creators: name: Nash, Anthony
name: Lokender Kumar
name: Harms, Chase
name: Planas-Iglesias, Joan
name: Wright, Derek
name: Klein-Seetharaman, Judith
name: Susanta K. Sarkar
Publisher: name: figshare
Year: 2021
Subjects: Biophysics
Computational Biology
Structural Biology

description: An understanding of the structure-dynamics relationship is essential for understanding how a protein works. Prior research has shown that the activity of a protein correlates with intradomain dynamics occurring at picosecond to millisecond timescales. However, the correlation between interdomain dynamics and the function of a protein is poorly understood. Here, we show that communications between the catalytic and hemopexin domains of matrix metalloprotease-1 (MMP1) on type 1 collagen fibrils correlate with its activity. Using single-molecule Förster resonance energy transfer, we identified functionally relevant open conformations in which the two MMP1 domains are well separated, which were significantly absent for catalytically inactive point mutant (E219Q) of MMP1 and could be modulated by an inhibitor or an enhancer of activity. The observed relevance of open conformations resolves the debate about the roles of open and closed MMP1 structures in function. We fitted the histograms of single-molecule Förster resonance energy transfer values to a sum of two Gaussians and the autocorrelations to an exponential and power law. We used a two-state Poisson process to describe the dynamics and calculate the kinetic rates from the fit parameters. All-atom and coarse-grained simulations reproduced some of the experimental features and revealed substrate-dependent MMP1 dynamics. Our results suggest that an interdomain separation facilitates opening up the catalytic pocket so that the collagen chains come closer to the MMP1 active site. Coordination of functional conformations at different parts of MMP1 occurs via allosteric communications that can take place via interactions mediated by collagen even if the linker between the domains is absent. Modeling dynamics as a Poisson process enables connecting the picosecond timescales of molecular dynamics simulations with the millisecond timescales of single-molecule measurements. Water-soluble MMP1 interacting with water-insoluble collagen fibrils poses challenges for biochemical studies that the single-molecule tracking can overcome for other insoluble substrates. Interdomain communications are likely important for multidomain proteins.
Synthesis and characterization of four diastereomers of β-lactamase inhibitor drug intermediate
Creators: name: Pund, Amit
name: Varangaonkar, Aniruddha
name: Rane, Vipul
name: Ahirrao, Vinod
name: Rafeeq, Mohammad
name: Yeole, Ravindra
name: Merwade, Arvind
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Information Systems not elsewhere classified

description: A short and efficient stereo-specific synthesis of three stereoisomers (two diastereomer and one enantiomer) of Oxalate salt of benzyl (2S,5R)-5-(benzyloxyamino)piperidine-2-carboxylate (8) has been described. Compound 8 is a key intermediate in the synthesis of β-lactamase inhibitors, was synthesized in high diastereomeric excess using chirally pure L-pyroglutamic acid. In this report, we also describe a chiral high performance liquid chromatography (CHPLC) method to separate these isomers. The developed CHPLC method was validated for the accurate determination of the diastereomeric purity of compound 8.
Chip-scale terahertz frequency combs through integrated intersubband polariton bleaching
Creators: name: Mezzapesa, Francesco P.
name: Viti, Leonardo
name: Li, Lianhe
name: Pistore, Valentino
name: Dhillon, Sukhdeep
name: Davies, A. Giles
name: Linfield, Edmund
name: Vitiello, Miriam S.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Quantum cascade lasers (QCLs) represent a fascinating accomplishment of quantum engineering and enable the direct generation of terahertz (THz) frequency radiation from an electrically-biased semiconductor heterostructure. Their large spectral bandwidth, high output powers and quantum-limited linewidths have facilitated the realization of THz pulses by active mode-locking and passive generation of optical frequency combs (FCs) through intracavity four-wave-mixing, albeit over a restricted operational regime. Here, we conceive an integrated architecture for the generation of high power (10 mW) THz FCs comprising an ultrafast THz polaritonic reflector, exploiting intersubband cavity polaritons, and a broad bandwidth (2.3-3.8 THz) heterogeneous THz QCL. Quantum cascade lasers (QCLs) represent a fascinating accomplishment of quantum engineering and enable the direct generation of terahertz (THz) frequency radiation from an electrically-biased semiconductor heterostructure. By tuning the group delay dispersion in an integrated geometry, through the exploitation of light induced bleaching of the intersubband-based THz polaritons, we demonstrate spectral reshaping of the QCL emission and stable FC operation over an operational dynamic range of up to 38%, characterized by a single and narrow (down to 700 Hz) intermode beatnote. Our concept provides design guidelines for a new generation of compact, cost-effective, electrically driven chip-scale FC sources based on ultrafast polariton dynamics, paving the way towards the generation of mode locked THz micro-lasers that will strongly impact a broad range of applications in ultrafast sciences, data storage, high-speed communication and spectroscopy.
description: 18 Pages, 7 figures, This is the authors' version of the article submitted to Laser & Photonics Reviews and accepted for publication (2021, 2000575)
One-loop graviton corrections to the curvature perturbation from inflation
Creators: name: Dimastrogiovanni, Emanuela
name: Bartolo, Nicola
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute one-loop corrections to the power spectrum of the curvature perturbation in single-field slow-roll inflation arising from gravitons and inflaton interactions. The quantum corrections due to gravitons to the power spectrum of the inflaton field are computed around the time of horizon crossing and their effect on the curvature perturbation is obtained on superhorizon scales through the delta-N formalism. We point out that one-loop corrections from the tensor modes are of the same magnitude as those coming from scalar self-interactions, therefore they cannot be neglected in a self-consistent calculation.
description: LateX file; 29 pages; typo corrected; comments added to Sec. 3 and 4. Matches published version in JCAP
Green and eco-friendly synthesis of quinolone substituted indolyl-4H-chromenes via C–C bond formation
Creators: name: Burra, Satish Kumar
name: Lakinani, Vaikunta Rao
name: Akula, Raghunadh
name: Yankkanti, Chiranjeevi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Virology

description: A novel and green strategy for the construction of biologically relevant substituted indolyl-4H-chromenes scaffolds is reported using L-proline as a catalyst and water as a promoter solvent. The catalytic system offers wider applicability, crossing over a variety of substrates, besides affording exclusively the desired product in shorter reaction times and high yields. L-proline-Water was found to be an efficient and cheaper catalytic system for regioselective synthesis of indolyl-4H-chromenes. The reaction between 4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carbaldehyde (1) with active methylene compounds (2a–b) and substituted indoles(3a–f) in the presence of L-proline afforded quinolone substituted indolyl-4H-chromenes (4a–l) in excellent yields. Furthermore, the reactions involve easy workup giving high yields without the need of column chromatography, making it one of the most ideal conditions for green chemistry.
Studio degli effetti dei nuovi metodi di trattamento sulle proprietà funzionali e strutturali dei materiali polimerici per il Food Packaging
Creators: name: Sansone, Lucia
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2008

description: Il packaging alimentare rappresenta un fattore chiave nella conservazione degli alimenti, da materiale usato come semplice contenitore, diventa sempre più un mezzo in grado di ridurre la velocità di decadimento qualitativo del prodotto, proteggendolo dalla contaminazione microbiologica e chimica.
Ovviamente affinché tali procedimenti di stabilizzazione degli alimenti raggiungano l'obiettivo di prolungare la shelf-life, la progettazione o la scelta dei materiali e dei sistemi di confezionamento deve essere particolarmente oculata. È necessario quindi conoscere le caratteristiche del prodotto da conservare e quelle dei materiali impiegati nel packaging, considerando tutte le possibili modificazioni che possono verificarsi nel periodo intercorrente tra la produzione ed il consumo.
Al fine di salvaguardare la salute del consumatore e le caratteristiche qualitative dell'alimento, é fondamentale conoscere la costituzione chimica ed il comportamento dei materiali utilizzati, nonché la natura e l'entità delle eventuali contaminazioni dovute a fenomeni di migrazione, cessioni di componenti ed additivi del materiale polimerico.
Spin susceptibility of superconductors with strong spin-orbit coupling
Creators: name: Samokhin, K. V.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We show that in some trigonal and hexagonal crystals the Zeeman coupling of band electrons with an external magnetic field is strongly anisotropic and necessarily vanishes along the main symmetry axis. This leads to qualitative changes in the temperature dependence of the electron spin susceptibility in the superconducting state. In particular, the power-law exponents at low temperatures due to the contribution of the nodal quasiparticles are considerably modified compared to their textbook values.
description: 15 pages
The carnitine and carnitine ester content of rat bile and human duodenal fluid
Creators: name: Hamilton, Jennifer Jane
Publisher: name: University of British Columbia
Year: 2010

description: Carnitine is necessary for the beta-oxidation of long-chain fatty acids. Carnitine esters are produced to transport fatty acids across the otherwise impermeable inner mitochondrial membrane. Although carnitine has been investigated in many tissues, the content and possible roles of carnitine in the gastrointestinal tract have not been completely investigated. The kinetics of carnitine absorption have been determined but the treatment and sources of carnitine in the intestinal tract are unknown. This study investigated the possible contribution of bile to the carnitine content of the intestinal lumen. First, the amounts of carnitine and carnitine esters in rat bile were measured. Then, the origin of carnitine in the bile was studied. Finally, the carnitine content of human bile-rich duodenal fluid was investigated. Bile was collected from eleven anaesthetized (pentobarbital) adult male rats. Bile flow was measured gravimetrically and carnitine and its esters were determined using a radiochemical carnitine assay. Specific types of carnitine esters were quantitated after first extracting the samples with chloroform and methanol. The origin of carnitine in the bile was investigated indirectly by measuring the carnitine content of bile from rats who were fasted for 72 hours or orally administered with tetradecylglycidic acid, an inhibitor of carnitine palmitoyltransferase I. These treatments differently affect the amounts and types of carnitine esters found in the liver and extrahepatically. The bile carnitine was compared to the serum and liver carnitine after these treatments to see if similarities existed. The origin of carnitine in the bile was further studied by administering [¹⁴C]carnitine intravenously and determining its recovery in the bile. Human bile-rich duodenal fluid was collected from ten patients with suspected cholelithiasis by duodenal aspiration using nasogastric intubation after pancreozymin-cholecystokinin injection. Large quantities of total carnitine and long-chain carnitine esters were found in rat bile relative to other tissues. It appears that carnitine enters the bile both directly from the newly synthesized or stored hepatic carnitine pool and also following hepatic uptake of carnitine from serum. The latter is first esterified in the liver before entering the bile. The types and amounts of carnitine esters in the bile, thus, appear to reflect the metabolic state at the time of bile formation. Carnitine was also found in human bile-rich duodenal fluid. The percentage of long-chain carnitine esters was similar to that found in rat bile. The discovery of carnitine in rat bile challenges the common assumption that only dietary carnitine is present in the intestinal tract. It also disputes the theory that urine is the sole route for carnitine excretion. In addition, it suggests that carnitine depletion could result if carnitine in the bile is not reabsorbed in the intestine. This might occur with general malabsorption syndromes.
Mutant knots with symmetry
Creators: name: Morton, H. R.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 57M25

description: Mutant knots, in the sense of Conway, are known to share the same Homfly polynomial. Their 2-string satellites also share the same Homfly polynomial, but in general their m-string satellites can have different Homfly polynomials for m>2. We show that, under conditions of extra symmetry on the constituent 2-tangles, the directed m-string satellites of mutants share the same Homfly polynomial for m<6 in general, and for all choices of m when the satellite is based on a cable knot pattern. We give examples of mutants with extra symmetry whose Homfly polynomials of some 6-string satellites are different, by comparing their quantum sl(3) invariants.
description: 15 pages
TA'LIM TIZIMIDA INNOVATSION METODLARNI TASHKIL ETISH VA UNING MUHIMLIGI
Creators: name: To`raqulova, Umida
name: To'raqulova, Mahliyo
Publisher: name: Zenodo
Year: 2023

description: Ushbu maqolada pedagogik jarayonni amalga oshirilishida innovatsion faoliyatning asosiy funktsiyasi, komponentlarini, maqsadi, ta’lim mazmuni, shakli, metodi, texnologiyasi, ta’lim vositalarini ta’lim mazmunini boyitgan holda o’zgartirish, shuningdek bu jarayonda axborot texnologiyalarining o’rni va ahamiyati haqida bayon etilgan.
Untersuchungen zur Wirtschaftlichkeit von Building Information Modeling (BIM) in der Planungs- und Realisierungsphase von Bauprojekten
Creators: name: Deubel, Maximilian
Publisher: name: KIT Scientific Publishing
Year: 2021
Subjects: Building Information Modeling
BIM
Anwendungsfälle
Nutzen
Aufwand
Wirtschaftlichkeit
use case
benefit
costs
efficiency

description: BIM wird als Chance gesehen, Bauprojekte verlässlicher fertigzustellen. Gleichzeitig werden verschiedene Herausforderungen diskutiert, die die Einführung erschweren. Bisher weniger im Fokus steht die Untersuchung der Wirtschaftlichkeit von BIM selbst. Ziel ist es daher, Aufwendungen und Nutzen von BIM bestimmbar zu machen. Im Ergebnis erhalten BIM-Anwender eine Hilfestellung, wie die Wirtschaftlichkeit einzelner BIM-Anwendungsfälle und damit in Summe von BIM bestimmt werden kann.
Performance Analysis and Optimization Opportunities for NVIDIA Automotive GPUs
Creators: name: Tabani, Hamid
name: Mazzocchetti, Fabio
name: Benedicte, Pedro
name: Abella, Jaume
name: Cazorla, Francisco J.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Hardware Architecture (cs.AR)
subject: FOS: Computer and information sciences

description: Advanced Driver Assistance Systems (ADAS) and Autonomous Driving (AD) bring unprecedented performance requirements for automotive systems. Graphic Processing Unit (GPU) based platforms have been deployed with the aim of meeting these requirements, being NVIDIA Jetson TX2 and its high-performance successor, NVIDIA AGX Xavier, relevant representatives. However, to what extent high-performance GPU configurations are appropriate for ADAS and AD workloads remains as an open question. This paper analyzes this concern and provides valuable insights on this question by modeling two recent automotive NVIDIA GPU-based platforms, namely TX2 and AGX Xavier. In particular, our work assesses their microarchitectural parameters against relevant benchmarks, identifying GPU setups delivering increased performance within a similar cost envelope, or decreasing hardware costs while preserving original performance levels. Overall, our analysis identifies opportunities for the optimization of automotive GPUs to further increase system efficiency.
A one-sided direct forcing immersed boundary method using moving least squares
Creators: name: Bale, Rahul
name: Bhalla, Amneet Pal Singh
name: Griffith, Boyce E.
name: Tsubokura, Makoto
Publisher: name: arXiv
Year: 2021
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: This paper presents a one-sided immersed boundary (IB) method using kernel functions constructed via a moving least squares (MLS) method. The resulting kernels effectively couple structural degrees of freedom to fluid variables on only one side of the fluid-structure interface. This reduces spurious feedback forcing and internal flows that are typically observed in IB models that use isotropic kernel functions to couple the structure to fluid degrees of freedom on both sides of the interface. The method developed here extends the original MLS methodology introduced by Vanella and Balaras (J Comput Phys, 2009). Prior IB/MLS methods have used isotropic kernel functions that coupled fluid variables on both sides of the boundary to the interfacial degrees of freedom. The original IB/MLS approach converts the cubic spline weights typically employed in MLS reconstruction into an IB kernel function that satisfies particular discrete moment conditions. This paper shows that the same approach can be used to construct one-sided kernel functions (kernel functions are referred to as generating functions in the MLS literature). We also examine the performance of the new approach for a family of kernel functions introduced by Peskin. It is demonstrated that the one-sided MLS construction tends to generate non-monotone interpolation kernels with large over- and undershoots. We present two simple weight shifting strategies to construct generating functions that are positive and monotone, which enhances the stability of the resulting IB methodology. Benchmark cases are used to test the order of accuracy and verify the one-sided IB/MLS simulations in both two and three spatial dimensions. This new IB/MLS method is also used to simulate flow over the Ahmed car model, which highlights the applicability of this methodology for modeling complex engineering flows.
description: In Press, Journal of Computational Physics (2021)
DEVELOPMENT OF CREATIVE IMAGINATION OF PEDAGOGICAL STUDENTS OF HIGHER EDUCATIONAL INSTITUTIONS
Creators: name: Boltaboyev, Ilxomjon
Publisher: name: Zenodo
Year: 2023

description: Today, as a result of the rapid development of Science and technology, the volume of scientific knowledge, understanding and imagination is sharply increasing. In such a society, the need for pedagogical personnel of creative quality is increasing and requires a high level of personal competence in them. In the process of modern education, the importance of higher education is considered important.
Heavy metal levels in grasses and legumes grown on Highland Valley Copper Mine tailings and the effect of artificial weathering on tailings growth production capability
Creators: name: Hackinen, Coleen Marie
Publisher: name: University of British Columbia
Year: 2010

description: Samples of agronomic grasses and legumes grown on copper mine tailings under two surficial amendment regimes and two fertilizer treatments were analyzed for Ca, Cu, Fe, K, Mg, Mn, Mo, N, Ni, P, and Zn. These values were compared to National Research Council and Agriculture Canada diet recommendations for beef cattle. Foliar Ca, Fe, Mn, Ni and P concentrations were satisfactory. Zn levels in most species were in the deficient range. Some samples contained excessive K or Mg, although overall foliar concentrations for these minerals were satisfactory. Copper and molybdenum concentrations were well above normal levels. Copper concentrations in the legumes and grasses averaged 63 and 44 mg/kg, respectively. Mean molybdenum concentrations were found to be 52 mg/kg in the grasses and 237 mg/kg in the legumes. Cu:Mo ratios in all species violated recommended dietary guidelines for beef cattle. Fluctuations in Cu:Mo ratios were attributable mainly to variations in foliar Cu. Most species were subjected to severe grazing by rodents, producing abnormal growth habits. As a result, assessment of relative species success was difficult. Grazing stress may also have affected foliar elemental levels. Tailings material was artificially weathered by leaching with 0.3 N acetic acid for seven weeks in a Soxhlet extraction chamber. Leached and unleached samples were analyzed for pH, 0.1 N HCl available Cu, Fe, Mn, Ni, and Zn, acid ammonium oxalate extractable Mo, total elemental levels and mineralogical composition. As a result of leaching, the pH of the tailings was reduced from 6.6 to 3.5. Declines in available Cu, Fe, Mn, Zn, and Mo were noted after leaching. No qualitative changes in tailings mineralogy were detected after artificial weathering. During leaching, three general elemental release patterns were observed. These were attributed to the sequential dissolution of readily soluble salts and carbonates, followed by the degradation of micas, pyroxenes, amphiboles and host ore minerals. The relatively inert minerals, such as, quartz, some alumino-silicates and oxyhydroxides of Fe and Al represented the third group. At present, the tailings are unsuitable as a forage production area for beef cattle as a result of toxic Cu:Mo ratios in the foliage. Based on chemical changes induced by artificial weathering, it is probable that forage grown on the tailings will become less toxic over time. Various management practices may be employed to accelerate improvement in growth medium parameters.