cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants
Creators: name: Pérez-Vargas, Jimena
name: Worrall, Liam J.
name: Olmstead, Andrea D.
name: Ton, Anh-Tien
name: Lee, Jaeyong
name: Villanueva, Ivan
name: Thompson, Connor A. H.
name: Dudek, Svenja
name: Ennis, Siobhan
name: Smith, Jason R.
name: Shapira, Tirosh
name: De Guzman, Joshua
name: Gang, Shutong
name: Ban, Fuqiang
name: Vuckovic, Marija
name: Bielecki, Michael
name: Kovacic, Suzana
name: Kenward, Calem
name: Hong, Christopher Yee
name: Gordon, Danielle G.
name: Levett, Paul N.
name: Krajden, Mel
name: Leduc, Richard
name: Boudreault, Pierre-Luc
name: Niikura, Masahiro
name: Paetzel, Mark
name: Young, Robert N.
name: Cherkasov, Artem
name: Strynadka, Natalie C. J.
name: Jean, François
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Antivirals with broad coronavirus activity are important for treating high-risk individuals exposed to the constantly evolving SARS-CoV-2 variants of concern (VOCs) as well as emerging drug-resistant variants. We developed and characterized a novel class of active-site-directed 3-chymotrypsin-like protease (3CLpro) inhibitors (C2-C5a). Our lead direct-acting antiviral (DAA), C5a, is a non-covalent, non-peptide with a dissociation constant of 170 nM against recombinant SARS-CoV-2 3CLpro. The compounds C2-C5a exhibit broad-spectrum activity against Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) and seasonal human coronavirus-229E infection in human cells. Notably, C5a has median effective concentrations of 30 – 50 nM against BQ.1.1 and XBB.1.5 in two different human cell lines. X-ray crystallography has confirmed the unique binding modes of C2-C5a to the 3CLpro, which can limit virus cross-resistance to emerging Paxlovid-resistant variants. We tested the effect of C5a with two of our newly discovered host-directed antivirals (HDAs): N-0385, a TMPRSS2 inhibitor, and bafilomycin D (BafD), a human vacuolar H+-ATPase [V-ATPase] inhibitor. We demonstrated a synergistic action of C5a in combination with N-0385 and BafD against Omicron BA.5 infection in human Calu-3 lung cells. Our findings underscore that a SARS-CoV-2 multi-targeted treatment for circulating Omicron subvariants based on DAAs (C5a) and HDAs (N-0385 or BafD) can lead to therapeutic benefits by enhancing treatment efficacy. Furthermore, the high-resolution structures of SARS-CoV-2 3CLpro in complex with C2-C5a will facilitate future rational optimization of our novel broad-spectrum active-site-directed 3C-like protease inhibitors.
LA MATERIALIZACIÓN DE LA AUTONOMÍA MUNICIPAL
Creators: name: Campos Campos, Oscar Gabriel
Publisher: name: DE IURE
Year: 2022

description: El Municipio tiene como una de sus características Constitucionales su “Autonomía”, pero ésta no es ni casualidad ni un invento Legal. La Autonomía del Municipio se define desde su propia naturaleza jurídica, desde la teoría general del Federalismo en el mundo. La autonomía municipal se concebirá entonces como la facultad de auto regularse administrativa, financiera y políticamente, es decir, la propia entidad municipal será la encargada de definir sus procesos administrativos, recaudar y erogar sus ingresos propios y tomar las decisiones sociales por sí mismos. Ahora bien, ¿Todas estas formas de Autonomía, se materializan en esta entidad con base en la Federación? Para contestar, resulta pertinente que se aborde a la Autonomía desde su concepción teórica profunda, hasta su estructura de facto de nuestros días. The Municipality has as one of its Constitutional features its "autonomy", but this is neither coincidence nor Legal invention. The Autonomy of the town is defined by its own legal status, from the general theory of federalism in the world. The municipal autonomy was then conceived as the empowering self regulated administratively, financially and politically; ie municipal entity itself is responsible for defining their business processes, collect and disburse its own revenue and make social decisions for themselves. Now, all these forms of autonomy, are embodied in this base entity of the Federation? to answer, it is pertinent to address deeply Theoretical Autonomy from conception to its structure de facto today.
description: DE IURE, Vol. 4 Núm. 2 (2022): Volumen 4, Número 2, Junio Año 2022
The inhomogeneous $p$-Laplacian equation with Neumann boundary conditions in the limit $p\to\infty$
Creators: name: Bungert, Leon
Publisher: name: arXiv
Year: 2021
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35D30, 35D40, 49Q22

description: We investigate the limiting behavior of solutions to the inhomogeneous $p$-Laplacian equation $-Δ_p u = μ_p$ subject to Neumann boundary conditions. For right hand sides which are arbitrary signed measures we show that solutions converge to a Kantorovich potential associated with the geodesic Wasserstein-$1$ distance. In the regular case with continuous right hand sides we characterize the limit as viscosity solution to an infinity Laplacian / eikonal type equation.
description: Corrected some typos
Female erectile organs and sexual dysfunction after radiotherapy: a scoping review
Creators: name: Marshall, Deborah
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medical Sciences
subject: Anatomy
subject: Other Medicine and Health Sciences
subject: Medicine and Health Sciences
subject: Medical Specialties
subject: Other Medical Specialties
subject: Oncology
subject: Medical Biophysics
subject: Reproductive and Urinary Physiology

description: The aim of this scoping review is to identify, categorize and report current research for the effect and related toxicities of radiotherapy on female erectile tissues.
title: Low dose CT for renal colic: How to do it?
Creators: name: Gervaise, Alban
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Radioprotection / Radiation dose
subject: Urinary Tract / Bladder
subject: CT
subject: Computer Applications-Detection, diagnosis
subject: Dosimetry
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To learn what is a low dose CT for renal colic. To show how to use low dose CT for renal colic in clinical practice. To discuss the different ways of reducing the CT radiation dose by considering both behavioural and technological...
title: CT evaluation : odontogenic origin causing obstructive maxillary sinusitis
Creators: name: Kim, Gihong
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Emergency
subject: Interventional vascular
subject: Interventional non-vascular
subject: CT-Angiography
subject: MR-Angiography
subject: MR-Diffusion/Perfusion
subject: Angioplasty
subject: Safety
subject: Arterial access
subject: Aneurysms
subject: Acute
subject: Dissection

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: According to previous study, Dr. yoshiura et al. reported that odontogenic maxillary sinusit is used in many situations where maxillary sinusitis and dental lesion co-exist and in korea, Sinusitis with an odontogenic source accounts for 10% of all...
title: Should the study of the pulmonary veins be systematic on coronary computed tomography angiography
Creators: name: Ben Amara, Imen
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Cardiac
subject: Anatomy
subject: CT-Angiography
subject: Decision analysis
subject: Haemodynamics / Flow dynamics

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Atrial fibrillation (AF)is the most common arythmia (1). Since the knowledge of the pathophysiologicalmechanisms underlying AF, a new technique consisting on percutaneous ablation hasemerged (2). This procedure requires an accurate anatomic mapping...
Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study
Creators: name: Coresh, Joe
name: Boerwinkle, Eric
name: Ballantyne, Christie M.
name: Mosley, Tom
name: Sharrett, A. Richey
name: Couper, David
name: Virani, Salim
name: Agarwala, Anandita
name: Folsom, Aaron R.
name: Hoogeveen, Ron C.
name: Chambless, Lloyd
name: Astor, Brad C.
name: Nambi, Vijay
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Biomarkers and atherosclerosis imaging have been studied individually for association with incident cardiovascular disease (CVD); however, limited data exist on whether the biomarkers are associated with events with a similar magnitude in the presence of atherosclerosis. In this study, we assessed whether the presence of atherosclerosis as measured by carotid intima media thickness (cIMT) affects the association between biomarkers known to be associated with coronary heart disease (CHD) and incident cardiovascular disease (CVD) in a primary prevention cohort.
The elusive quantum anomalous Hall effect in MnBi2Te4: a materials perspective
Creators: name: Yan, Jiaqiang
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Observation of the quantum anomalous Hall effect (QAHE) in MnBi$_2$Te$_4$ flakes is one of the most exciting results in the study of the intrinsic magnetic topological insulator MnBi$_2$Te$_4$ and related compounds. This fascinating result is yet to be reproduced two years after its first report. The quality of starting MnBi$_2$Te$_4$ single crystals is believed to be the key factor. An interesting and important question to address is what is the right quality to enable the QAHE. In this perspective, we present possible approaches to tuning the magnetic and topological properties of MnBi$_2$Te$_4$ by using lattice imperfections, strain, stacking sequence, and interactions between the substrate and flakes/films. It is of critical importance to eventually identify the factor(s) responsible for the realization of QAHE.
description: 4 pages, 2 figures, submitted to ECS JSS focus issue honoring John Goodenough's 100th birthday
title: Diffusion-weighed MR imaging in autoimmune pancreatitis
Creators: name: Di Caro, Vanesa
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Pancreas
subject: MR-Diffusion/Perfusion
subject: MR
subject: Imaging sequences
subject: Inflammation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Autoimmune pancreatitis (AIP) is a disease that is being increasingly recognized as a distinct clinical entity worldwide 1,2 . AIP can occur as a primary disease of the pancreas or as part of a systemic disease associated with elevations in levels...
The uniqueness-of-norm problem for Calkin algebras
Creators: name: Skillicorn, Richard
Publisher: name: arXiv
Year: 2015
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: We examine the question of whether the Calkin algebra of a Banach space must have a unique complete algebra norm. We present a survey of known results, and make the observation that a recent Banach space construction of Argyros and Motakis (preprint, 2015) provides the first negative answer. The parallel question for the weak Calkin algebra also has a negative answer; we demonstrate this using a Banach space of Read (J. London Math. Soc. 1989).
Ankle-brachial index and physical function in older individuals: The Atherosclerosis Risk in Communities (ARIC) study
Creators: name: Heiss, Gerardo
name: Selvin, Elizabeth
name: Kalbaugh, Corey
name: Tanaka, Hirofumi
name: Hirsch, Alan T.
name: Loehr, Laura R.
name: Matsushita, Kunihiro
name: Sang, Yingying
name: Ballew, Shoshana H.
name: Windham, B. Gwen
name: Coresh, Josef
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Most prior studies investigating the association of lower extremity peripheral artery disease (PAD) with physical function were small or analyzed selected populations (e.g., patients at vascular clinics or persons with reduced function), leaving particular uncertainty regarding the association in the general community.
Prospective study of lung function and abdominal aortic aneurysm risk: The Atherosclerosis Risk in Communities study
Creators: name: Tang, Weihong
name: Kubota, Yasuhiko
name: Folsom, Aaron R.
name: Couper, David
name: Matsushita, Kunihiro
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Abstract Background and aims No prospective study has investigated whether individuals with respiratory impairments, including chronic obstructive pulmonary disease (COPD) and restrictive lung disease (RLD), are at increased risk of abdominal aortic aneurysm (AAA). We aimed to prospectively investigate whether those respiratory impairments are associated with increased AAA risk. Methods In 1987–1989, the Atherosclerosis Risk in Communities (ARIC) study followed 14,269 participants aged 45–64 years, without a history of AAA surgery, through 2011. Participants were classified into four groups, “COPD” [forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) <lower limit of normal (LLN)], “RLD” (FEV1/FVC ≥ LLN and FVC < LLN), “respiratory symptoms with normal spirometry” (without RLD or COPD), and “normal” (without respiratory symptoms, RLD or COPD, reference group). Results During the 284,969 person-years of follow-up, 534 incident AAA events were documented. In an age, sex, and race-adjusted proportional hazards model, individuals with respiratory impairments had a significantly higher risk of AAA than the normal reference group. After adjustment for AAA risk factors, including smoking status and pack-years of smoking, AAA risk was no longer significant in the respiratory symptoms with normal spirometry group [HR (95% CI), 1.25 (0.98–1.60)], but was still increased in the other two groups [RLD: 1.45 (1.04–2.02) and COPD: 1.66 (1.34–2.05)]. Moreover, continuous measures of FEV1/FVC, FEV1 and FVC were associated inversely with risk of AAA. Conclusions In the prospective population-based cohort study, obstructive and restrictive spirometric patterns were associated with increased risk of AAA independent of smoking, suggesting that COPD and RLD may increase the risk of AAA. Highlights • No prospective study has examined the association between lung function and abdominal aortic aneurysm (AAA). • We examined this association using a prospective population-based study in the US. • Chronic obstructive pulmonary disease (COPD) and restrictive diseases patterns were associated with increased AAA risk. • This study suggested COPD and restrictive lung diseases may increase AAA risk.
CZECH REPUBLIC - Migration and demographic patterns in Central-Eastern Europe
Creators: name: Magdziarz, Wiktor
name: Pędziwiatr, Konrad
name: Sikorska, Joanna
Publisher: name: Zenodo
Year: 2023
Subjects: migration
Czech republic
migration scenarios

description: This report has been prepared as a part of the Horizon 2020 FUME project – Future Migration Scenarios for Europe (870649) and its deliverable “D.6.3. Report on migration and demographic patterns in the EU CEE countries and potential source countries”. It aims to analyse the migration profile of Czechia and to assess the country’s migration potential in order to provide material for the fine-tuning of the FUME migration projection model. Some of the variables the report takes into account are gender, age, country of origin and destination countries. The report is a first step in the analytical exercise which aims to determine migration movement potential both from and to the Czech Republic.
 For Czech Republic, analogously to other Visegrad Group states, international migration is a phenomenon that over the last few years became substantially important politically, demographically and economically. The development of the migration policy has been taking place in the country since the 1990s. While the Czech economy has been experiencing increasing demand for foreign labour, the mainstream public narrative concerning immigrants (and asylum seekers in particular) and, consequently, shaping migration policy agenda, has been, especially recently, predominantly a securitarian one.
 Some of the key moments concerning international migrations in the country’s recent history are the accession of Czechia to the European Union in 2004 and entering the Schengen Area three years later. The largest group of immigrants in the country is the group of Ukrainian citizens. Undoubtedly, the Russian annexation of Crimea and a military attack on Eastern Ukraine which subsequently led to the protracted armed conflict, has enhanced the inflow of Ukrainian migrants to the country and affected the structure of residence permits held by the nationals of this country, as we point out further in this analysis.
 This report aims to briefly present the historical background for migration movements in the Czech Republic, in order to provide a better understanding of current challenges Czech society faces with regard to increased migration movements in general and immigration in particular. The authors of this report provide a general outline of the demography of migrant groups currently residing in Czechia. A separate part of this paper is focusing on the issue of the Czech diaspora globally. Apart from those, the authors of the report sketch a general analysis of migration policies introduced in Czechia. Finally, local data gathered from the Czech sources are juxtaposed with Guy Abel’s calculations and, based on those, a quantitative analysis of migration movements to and from the country is conducted.
Ab initio studies on the lattice thermal conductivity of silicon clathrate frameworks II and VIII
Creators: name: Härkönen, Ville J.
name: Karttunen, Antti J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The lattice thermal conductivities of silicon clathrate frameworks II and VIII are investigated by using ab initio lattice dynamics and iterative solution of the linearized Boltzmann transport equation(BTE) for phonons. Within the temperature range 100-350 K, the clathrate structures II and VIII were found to have lower lattice thermal conductivity values than silicon diamond structure (d-Si) by factors of 1/2 and 1/5, respectively. The main reason for the lower lattice thermal conductivity of the clathrate structure II in comparison to d-Si was found to be the harmonic phonon spectra, while in the case of the clathrate structure VIII, the difference is mainly due to the harmonic phonon spectra and partly due to shorter relaxation times of phonons. In the studied clathrate frameworks, the anharmonic effects have larger impact on the lattice thermal conductivity than the size of the unit cell. For the structure II, the predicted lattice thermal conductivity differs approximately by factor of 20 from the previous experimental results obtained for a polycrystalline sample at room temperature.
description: 12 pages, 5 figures. The lattice thermal conductivities, relaxation times and related quantities have been recalculated. Noticeable changes in results are for the clathrate structure VIII
Mixed Hegselmann-Krause Dynamics II
Creators: name: Li, Hsin-Lun
Publisher: name: arXiv
Year: 2021
Subjects: subject: Dynamical Systems (math.DS)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 05C40, 05C90, 37N99, 60G42, 91C20, 91D25, 91D30, 93D50, 94C15

description: The mixed Hegselmann-Krause (HK) model consists of a finite number of agents characterized by their opinion, a vector in $\mathbf{R^d}$. For the deterministic case, each agent updates its opinion by the rule: decide its degree of stubbornness and mix its opinion with the average opinion of its neighbors, the agents whose opinion differs by at most some confidence threshold from its opinion at each time step. The mixed model is studied deterministically in \cite{mHK}. In this paper, we study it nondeterministically and involve a social relationship among the agents which can vary over time. We investigate circumstances under which asymptotic stability holds. Furthermore, we indicate the mixed model covers not only the HK model but also the Deffuant model.
description: 7 pages
"Hard" crystalline lattice in the Weyl semimetal NbAs
Creators: name: Luo, Yongkang
name: Ghimire, N. J.
name: Bauer, E. D.
name: Thompson, J. D.
name: Ronning, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report the effect of hydrostatic pressure on the magnetotransport properties of the Weyl semimetal NbAs. Subtle changes can be seen in the $ρ_{xx}(T)$ profiles with pressure up to 2.31 GPa. The Fermi surfaces undergo an anisotropic evolution under pressure: the extremal areas slightly increase in the $\mathbf{k_x}$-$\mathbf{k_y}$ plane, but decrease in the $\mathbf{k_z}$-$\mathbf{k_y}$($\mathbf{k_x}$) plane. The topological features of the two pockets observed at atmospheric pressure, however, remain unchanged at 2.31 GPa. No superconductivity can be seen down to 0.3 K for all the pressures measured. By fitting the temperature dependence of specific heat to the Debye model, we obtain a small Sommerfeld coefficient $γ_0=$ 0.09(1) mJ/(mol$\cdot$K$^2$) and a large Debye temperature, $Θ_D=$ 450(9) K, confirming a "hard" crystalline lattice that is stable under pressure. We also studied the Kadowaki-Woods ratio of this low-carrier-density massless system, $R_{KW}=$ 3.2$\times 10^4$ $μΩ$ cm mol$^2$ K$^2$ J$^{-2}$. After accounting for the small carrier density in NbAs, this $R_{KW}$ indicates a suppressed transport scattering rate relative to other metals.
description: 12 pages, 5 figures, 1 table
title: Differential diagnosis of Frontotemporal Dementia FTLD using visual rating scales
Creators: name: Manouvelou, Stamo
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Dementia
subject: Comparative studies
subject: MR
subject: Neuroradiology brain

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Aims and objectives Frontotemporal lobar degeneration (FTLD) represents the second most common early onset of neurodegenerative dementia in those less than 65 years of age [1]. The overlap between different kinds of Frontotemporal dementia is...
Constraining condensed-phase formation kinetics of secondary organic aerosol  components from isoprene epoxydiols
Creators: name: Thornton,
name: Chu,
name: Gold,
name: Lin,
name: Zhang,
name: Vizuete,
name: Surratt,
name: Riedel,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Isomeric epoxydiols from isoprene photooxidation (IEPOX) have been shown to produce substantial amounts of secondary organic aerosol (SOA) mass and are therefore considered a major isoprene-derived SOA precursor. Heterogeneous reactions of IEPOX on atmospheric aerosols form various aerosol-phase components or "tracers" that contribute to the SOA mass burden. A limited number of the reaction rate constants for these acid-catalyzed aqueous-phase tracer formation reactions have been constrained through bulk laboratory measurements. We have designed a chemical box model with multiple experimental constraints to explicitly simulate gas- and aqueous-phase reactions during chamber experiments of SOA growth from IEPOX uptake onto acidic sulfate aerosol. The model is constrained by measurements of the IEPOX reactive uptake coefficient, IEPOX and aerosol chamber wall losses, chamber-measured aerosol mass and surface area concentrations, aerosol thermodynamic model calculations, and offline filter-based measurements of SOA tracers. By requiring the model output to match the SOA growth and offline filter measurements collected during the chamber experiments, we derive estimates of the tracer formation reaction rate constants that have not yet been measured or estimated for bulk solutions.
EVOLUCIÓN Y FUNDAMENTOS TEORICOS DEL DERECHO INTERNACIONAL
Creators: name: Miranda, Agustin Aguilera
Publisher: name: DE IURE
Year: 2022

description: El derecho internacional ha sido cuestionado por considerársele como imperfecto, gracias a que carece de una autoridad que lo aplique y lo haga valer, lo que implica que en algunas circunstancias sea aplicado con toda rigurosidad y en otros casos sin gran impacto. Además de que consideramos que aún tiene áreas desconocidas sobre todo en lo referente al intercambio del derecho comparativo o del derecho convencional. Temas como la substanciación del proceso que coadyuban en la impartición de justicia de manera internacional no es un tema muy estudiado. Sin duda alguna México tiene grandes maestros en el ámbito del derecho internacional que se han preocupado y se han adentrado en su estudio y en difundir los resultados de sus conocimientos, sin embargo, en nuestra opinión falta que el derecho internacional tenga un mayor impacto y sobre todo el alcance deseado que pueda ser un derecho eficaz, que sea acatado por todos los países y se aplicara verdaderamente el respeto entre las naciones. Con el presente artículo, buscamos realizar un análisis del origen y los elementos más relevantes del derecho internacional y con sucesivos artículos plantearemos la importancia de esta materia que por desconocimiento no se ha apreciado su verdadera trascendencia, sobre todo en nuestro país ya que adopta a los tratados internacionales en el mismo rango que la constitución, tras la reforma del 10 de junio del año 2011, en la que se otorgan los derechos humanos en ligar de las garantías individuales.
description: DE IURE, Vol. 4 Núm. 2 (2022): Volumen 4, Número 2, Junio Año 2022
title: A Scoping Review on the Experiences of Queer and Trans Students in STEM
Creators: name: Tingey, Elliot P.
Publisher: name: Utah State University
Year: 2024

description: Efforts to increase diversity in STEM (science, technology, engineering, and mathematics) are ongoing, but within these efforts queer and trans individuals are often left out. While initial data does suggest that queer and trans individuals are significantly absent from the STEM workforce, research into the causes of such underrepresentation is scattered. Given the importance of educational experiences in the pursuit of a STEM career, it is likely that these early experiences may play a role. Therefore, the purpose of this paper is to investigate the current research on the experiences of queer and trans students in STEM educational spaces, what methods are best for supporting them, and where more research is needed. To that end this study employs the use of scoping review methodology in order to draw conclusions from a wide variety of studies. Data was organized into broad categories so as to draw qualitative descriptions of the current literature. This analysis revealed that overall, the experiences of queer and trans students in STEM are primarily negative, dominated by invisibility and isolation created by cultures of that prioritize and normalize cisgender and heterosexual perspectives and experiences and are therefore unwelcoming of queer and trans identities. More research is needed in order to determine how to improve the experiences of queer and trans students in STEM, but acknowledgements of queer and trans identities within STEM spaces as well as queer affinity groups do seem to have some positive impact for students. Other gaps in the literature identified include a significant lack of research on K-12 queer and trans students in STEM as well as the need for studies specific to trans students, those of specific queer identities, and those engaged in specific STEM fields as well as intersectional studies. Recommendations for research and practice are included.
Gravitational waves from dark matter collapse in a star
Creators: name: Kurita, Yasunari
name: Nakano, Hiroyuki
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the collapse of clusters of weakly interacting massive particles (WIMPs) in the core of a Sun-like star and the possible formation of mini-black holes and the emission of gravitational waves. When the number of WIMPs is small, thermal pressure balances the WIMP cluster's self gravity. If the number of WIMPs is larger than a critical number, thermal pressure cannot balance gravity and the cluster contracts. If WIMPs are collisionless and bosonic, the cluster collapses directly to form a mini-black hole. For fermionic WIMPs, the cluster contracts until it is sustained by Fermi pressure, forming a small compact object. If the fermionic WIMP mass is smaller than $4\times 10^2$ GeV, the radius of the compact object is larger than its Schwarzschild radius and Fermi pressure temporally sustains its self gravity, halting the formation of a black hole. If the fermionic WIMP mass is larger than $4\times 10^2$ GeV, the radius is smaller than its Schwarzschild radius and the compact object becomes a mini-black hole. If the WIMP mass is 1 TeV, the size of the black hole will be approximately 2.5 cm and ultra high frequency gravitational waves will be emitted during black hole formation. The central frequency $f_c$ of ringdown gravitational waves emitted from the black hole will be approximately 2 GHz. To detect the ringdown gravitational waves, the detector's noise must be below $\sqrt{S_h(f_c)}\approx 10^{-30}/\sqrt{\rm Hz}$.
description: 25 pages, 5 figures, typos corrected, comments added. Version accepted by PRD
Holomorphic reflexivity for locally finite and profinite groups: the abelian and general cases
Creators: name: Aristov, Oleg
Publisher: name: arXiv
Year: 2021
Subjects: subject: Rings and Algebras (math.RA)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: Akbarov's theory of holomorphic reflexivity for topological Hopf algebras has been developed in two directions, namely, by the complication of definitions when expanding the scope and by their simplification when restricting. In the framework of the latter approach, we establish the holomorphic reflexivity for topological Hopf algebras associated with locally finite countable groups and second-countable profinite groups. In the Abelian case, the reflexivity is described in terms close to the classical ones.
description: version 4: English transl (by Math. Notes), earlier versions in Russian, version 3: Introduction rewritten
Positivity vs. slope semistability for bundles with vanishing discriminant
Creators: name: Fulger, Mihai
name: Langer, Adrian
Publisher: name: arXiv
Year: 2021
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14C17, 14C20, 14F06, 14H60, 14N05

description: We give an algebraic proof valid in arbitrary characteristic for the known equivalence between (strongly) slope semistable vector bundles with vanishing discriminant and vanishing determinant and numerically flat bundles. We also address a related question of Misra.
description: Second named author added. The main results are extended to arbitrary characteristic. A new counterexample to Misra's question added. An optimistic application of the Mehta-Ramanathan theorem in Corollary 3.2 of the initial submission has been corrected
title: Imaging features of abdominal epiploic ischemic lesions
Creators: name: Ben Farhat, Leila
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Abdomen
subject: CT
subject: Diagnostic procedure
subject: Ischaemia / Infarction

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: ‐ To describe the clinical presentation of ischemic epiploic intra-abdominal lesions. ‐ To illustrate the imaging features in ultrasound and CT scan of epiploic appendagitis and omental...
title: Supporting young people's experience of preparing to leave children's homes to live independently : implications for leadership - a view from practice
Creators: name: O'Brien, Nat
Publisher: name: Strathprints - University of Strathclyde
Year: 2015

description: This paper considers the value of shared leadership and co-production techniques when enabling young people to progress towards independence. Two examples are discussed to illustrate where this worked particularly well in bringing about developments in practice. The first relates to identifying goals for change for young people: My Steps to Success. The second focuses on the production of 'young people friendly' pathway plans. The paper concludes by thinking about some of the ways shared leadership can serve to improve the experiences of young people who are preparing to leave residential care to live independently.
title: A prospective study of patient perception of pain and satisfaction, with regards to sedation, during interventional radiology procedures
Creators: name: Clifford, Simon
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Interventional vascular
subject: Interventional non-vascular
subject: Management
subject: Fluoroscopy
subject: CT
subject: Ultrasound
subject: Perception image
subject: Efficacy studies
subject: Outcomes analysis
subject: Drugs / Reactions
subject: Outcomes
subject: Quality assurance

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The purpose of this studywas to prospectively assess patient perception of pain and satisfaction for Interventional Radiological (IR) procedures [1]. This included interventional fluoroscopy, interventionalcomputed tomography (CT)...
Project ENHANCE
Creators: name: Lane, Kathleen
name: Buckman, Mark
name: Schatschneider, Chris
name: Oakes, Wendy
name: Common, Eric
name: Briesch, Amy
name: Hicks, Tyler
name: Royer, David
name: Chafouleas, Sandra
Publisher: name: Open Science Framework
Year: 2022

description: Project ENHANCE: Assessing Professional Learning Needs for Ci3T
Stability of variable-step BDF2 and BDF3 methods
Creators: name: Li, Zhaoyi
name: Liao, Hong-lin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65M06, 65M12

description: We prove that the two-step backward differentiation formula (BDF2) method is stable on arbitrary time grids; while the variable-step BDF3 scheme is stable if almost all adjacent step ratios are less than 2.553. These results relax the severe mesh restrictions in the literature and provide a new understanding of variable-step BDF methods. Our main tools include the discrete orthogonal convolution kernels and an elliptic-type matrix norm.
description: 20 pages, 2 figures, 3 tables
Were we erring? The impact of worry and arousal on error‐related negativity in a non‐clinical sample
Creators: name: Härpfer, Kai
name: Carsten, Hannes Per
name: Spychalski, Daniel
name: Kathmann, Norbert
name: Riesel, Anja
Publisher: name: Humboldt-Universität zu Berlin
Year: 2020
Subjects: subject: action monitoring
subject: anxiety
subject: arousal
subject: ERN
subject: ERPs
subject: worry
subject: 150 Psychologie

description: The monitoring of one's own actions allows humans to adjust to a changing and complex world. Previous neuroscientific research found overactive action monitoring and increased sensitivity to errors to be associated with anxiety and it is assumed to contribute to the development and maintenance of anxiety symptoms. A largely shared decomposition of anxiety differentiates two dimensions: anxious apprehension (i.e., worry) and anxious arousal (i.e., physiological hyperarousal). Alterations in neural correlates of error monitoring have been more closely linked to anxious apprehension compared to anxious arousal. This study examined the relationship between anxiety dimensions and electrophysiological correlates of action monitoring (i.e., error‐related negativity, ERN, and correct‐response negativity, CRN). A total of 135 non‐clinical participants performed a flanker task while their electroencephalogram was recorded. We recruited participants with converging and diverging anxiety dimension profiles (i.e., above or below median in anxious apprehension and anxious arousal or above median in one and below in the other dimension). This grouping strategy facilitates disentangling possible interactions and allows the investigation of the isolated effect of each anxiety dimension. Regression analyses did not reveal a significant main or interaction effect of anxiety dimensions on ERN or CRN, irrespective of gender. In addition, Bayesian statistical analyzes yielded evidence for the absence of an association between both anxiety dimensions and ERN and CRN. Altogether, our results suggest that the association of anxiety dimensions, particularly anxious apprehension, and action monitoring might be smaller in non‐clinical samples as previous studies indicate.
Forming the Cold Classical Kuiper Belt in a light Disk
Creators: name: Shannon, Andrew
name: Wu, Yanqin
name: Lithwick, Yoram
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Large Kuiper Belt Objects are conventionally thought to have formed out of a massive planetesimal belt that is a few thousand times its current mass. Such a picture, however, is incompatible with multiple lines of evidence. Here, we present a new model for the conglomeration of Cold Classical Kuiper belt objects, out of a solid belt only a few times its current mass, or a few percent of the solid density in a Minimum Mass Solar Nebula. This is made possible by depositing most of the primordial mass in grains of size centimetre or smaller. These grains collide frequently and maintain a dynamically cold belt out of which large bodies grow efficiently: an order-unity fraction of the solid mass can be converted into large bodies, in contrast to the ~0.1% efficiency in conventional models. Such a light belt may represent the true outer edge of the Solar system, and it may have effectively halted the outward migration of Neptune. In addition to the high efficiency, our model can also produce a mass spectrum that peaks at an intermediate size, similar to the observed Cold Classicals, if one includes the effect of cratering collisions. In particular, the observed power-law break observed at ~30 km for Cold Classicals, one that has been interpreted as a result of collisional erosion, may be primordial in origin.
description: Accepted version, ApJ
A Griggs apparatus Upgrade for Stress-Controlled Testing of Geological Material at High Temperature and Pressure
Creators: name: soleymani, Hamidreza
name: Kidder, Steven
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Physical Sciences and Mathematics
subject: Materials Science and Engineering
subject: Earth Sciences
subject: Engineering

description: LabVIEW graphic script files, image of the script and wiring diagram used for Griggs apparatus upgrade
Seasonal characterization of submicron aerosol chemical composition and organic aerosol sources in the southeastern United States: Atlanta, Georgia,and Look Rock, Tennessee
Creators: name: Gold, Avram
name: Bairai, Solomon T.
name: Mueller, Stephen
name: Edgerton, Eric S.
name: Budisulistiorini, Sri Hapsari
name: Baumann, Karsten
name: Surratt, Jason D.
name: Knipping, Eladio M.
name: Shaw, Stephanie L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: A year-long near-real-time characterization of non-refractory submicron aerosol (NR-PM1) was conducted at an urban (Atlanta, Georgia, in 2012) and rural (Look Rock, Tennessee, in 2013) site in the southeastern US using the Aerodyne Aerosol Chemical Speciation Monitor (ACSM) collocated with established air-monitoring network measurements. Seasonal variations in organic aerosol (OA) and inorganic aerosol species are attributed to meteorological conditions as well as anthropogenic and biogenic emissions in this region. The highest concentrations of NR-PM1 were observed during winter and fall seasons at the urban site and during spring and summer at the rural site. Across all seasons and at both sites, NR-PM1 was composed largely of OA (up to 76 %) and sulfate (up to 31 %). Six distinct OA sources were resolved by positive matrix factorization applied to the ACSM organic mass spectral data collected from the two sites over the 1 year of near-continuous measurements at each site: hydrocarbon-like OA (HOA), biomass burning OA (BBOA), semi-volatile oxygenated OA (SV-OOA), low-volatility oxygenated OA (LV-OOA), isoprene-derived epoxydiols (IEPOX) OA (IEPOX-OA) and 91Fac (a factor dominated by a distinct ion at m∕z 91 fragment ion previously observed in biogenic influenced areas). LV-OOA was observed throughout the year at both sites and contributed up to 66 % of total OA mass. HOA was observed during the entire year only at the urban site (on average 21 % of OA mass). BBOA (15–33 % of OA mass) was observed during winter and fall, likely dominated by local residential wood burning emission. Although SV-OOA contributes quite significantly ( ∼  27 %), it was observed only at the urban site during colder seasons. IEPOX-OA was a major component (27–41 %) of OA at both sites, particularly in spring and summer. An ion fragment at m∕z 75 is well correlated with the m∕z 82 ion associated with the aerosol mass spectrum of IEPOX-derived secondary organic aerosol (SOA). The contribution of 91Fac to the total OA mass was significant (on average 22 % of OA mass) at the rural site only during warmer months. Comparison of 91Fac OA time series with SOA tracers measured from filter samples collected at Look Rock suggests that isoprene oxidation through a pathway other than IEPOX SOA chemistry may contribute to its formation. Other biogenic sources could also contribute to 91Fac, but there remains a need to resolve the exact source of this factor based on its significant contribution to rural OA mass.
Replication of Abel & Kruger (2010) Psychological Science
Creators: name: Dufner, Michael
name: Schmukle, Stefan
name: Brümmer, Martin
name: Chung, Joanne
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: longevity
subject: positive affect
subject: replication
subject: smiling

description: We are trying to replicate the findings of this article: Abel, E. L., & Kruger, M. L. (2010). Smile intensity in photographs predicts longevity. Psychological Science, 21(4), 542-544.
La Salud Publica en México y el Municipio
Creators: name: Rodriguez Valadez, Juan Manuel
Publisher: name: DE IURE
Year: 2022

description: La descentralización de los servicios de salud a nivel municipal fue una posibilidad que se planteó en la primera etapa del proceso en la década de los ochenta como respuesta a la promoción de establecer el municipio libre para el fortalecimiento del federalismo derivada de la reforma al artículo 115 constitucional publicada en el Diario Oficial de la Federación el 3 de febrero de 1983. Sin embargo, hay que recordar que el proceso de descentralización hacia los estados fue complicado y en la primera etapa ni siquiera logró concretarse en todo el país, por tanto, uno de los primeros aspectos a considerar antes de iniciar el procedimiento es la desigualdad que existe entre los municipios. La salud es causa y efecto del desarrollo. No puede mirarse a la salud como resultado automático del crecimiento económico, como si entre éste y el desarrollo social hubiera una relación ordinal. Por el contrario, salud y desarrollo están sujetos a una severa regla de concomitancia que lleva a que se muevan juntos y en la misma dirección, pues no hay pueblos saludables sin desarrollo y éste no puede darse con bajos niveles de salud.
description: DE IURE, Vol. 4 Núm. 2 (2022): Volumen 4, Número 2, Junio Año 2022
title: Stents change the life of cancer patients
Creators: name: Morita, Shinichi
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Abdomen
subject: Biliary Tract / Gallbladder
subject: Gastrointestinal tract
subject: CT
subject: Fluoroscopy
subject: Stents
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1.To review the different characteristics of various metallic stents. 2.To understand the indications, selection criteria, and placement techniques for metallic stents in patients with cancer. 3.To introduce the three important functions of metallic...
Path Integral approach to nonequilibrium potentials in multiplicative Langevin dynamics
Creators: name: Barci, Daniel G.
name: Arenas, Zochil González
name: Moreno, Miguel Vera
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We present a path integral formalism to compute potentials for nonequilibrium steady states, reached by a multiplicative stochastic dynamics. We develop a weak-noise expansion, which allows the explicit evaluation of the potential in arbitrary dimensions and for any stochastic prescription. We apply this general formalism to study noise-induced phase transitions. We focus on a class of multiplicative stochastic lattice models and compute the steady state phase diagram in terms of the noise intensity and the lattice coupling. We obtain, under appropriate conditions, an ordered phase induced by noise. By computing entropy production, we show that microscopic irreversibility is a necessary condition to develop noise-induced phase transitions. This property of the nonequilibrium stationary state has no relation with the initial stages of the dynamical evolution, in contrast with previous interpretations, based on the short-time evolution of the order parameter.
description: 6 pages, 1 figure. Final version accepted for publication in EPL