cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Role of the Ste20-like Kinase in Embryonic Development and Neu-induced Mammary Tumorigenesis
Creators: name: Al-Zahrani, Khalid
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2018
Subjects: SLK
Breast Cancer
HER2
Sox10

description: Over the past two decades, the mammalian Ste20-like kinase (SLK) has been characterized for its role in regulating cellular migration, proliferation and apoptosis in fibroblasts and myoblasts. In mammary epithelial cells, SLK has been shown to be required for efficient epithelial-to-mesenchymal transition and to be activated downstream of the HER2/Neu-oncogene to control chemotactic cellular migration. Here, we assessed the role of SLK in HER2/Neu-induced mammary tumorigenesis in vivo. As SLK is activated downstream of HER2/Neu, we hypothesized that the loss of SLK would significantly delay tumor progression in a mouse model of HER2-positive breast cancer. As we have shown that global attenuation of SLK kinase activity results in embryonic lethality, a conditional SLK knockout mouse model was generated. To study the role of SLK in HER2-positive breast cancer, we crossed these conditional SLK knockout mice with mice expressing HER2/Neu linked to Cre recombinase in the mammary luminal epithelium. Unexpectedly, we have demonstrated that conditional deletion of SLK significantly accelerates Neu-induced mammary tumor onset and decreases overall survival. SLK deletion results in the induction of Sox10 which drives mammary stem/progenitor activity and cooperates with HER2/Neu to drive tumor growth. Using the Cancer Genome Atlas, we have supported previous findings and validated Sox10 as a potential biomarker of the Triple-negative Breast Cancer subtype. Furthermore, we have uncovered that SLK deletion results in enhanced activation of both PDK1 and AKT. We provide evidence that Sox10 induction requires signaling through a novel AKT/Sox9-dependent pathway following SLK deletion. Taken together, our data suggests that SLK may be required to maintain cells in a fully differentiated state and that loss of SLK in HER2/Neu-induced breast cancer drives a more basal/stem-like phenotype through the induction of Sox10.
Diversity investigation by application of DNA barcoding: a case study of lepidopteran insects in Xinjiang wild fruit forests, China
Creators: name: Zhan, Jinyu
name: Zheng, Yufeng
name: Xia, Qing
name: Wang, Jin
name: Liu, Sibo
name: Yang, Zhaofu
Publisher: name: Zenodo
Year: 2023

description: To investigate the species diversity of lepidopteran insects in Xinjiang wild fruit forests, establish insect community monitoring systems and determine the local species pool, we test the applicability of DNA barcoding based on cytochrome c oxidase subunit I (COI) gene for accurate and rapid identification of insect species. From 2017 to 2019, a total of 212 samples with ambiguous morphological identification were selected for DNA barcoding analysis. Five sequence-based methods for species delimitation (ABGD, BINs, GMYC, jMOTU and bPTP) were conducted for comparison to traditional morphology-based identification. In total, 2,422 samples were recorded, representing 143 species of 110 genera in 17 families in Lepidoptera. The diversity analysis showed that the richness indices for Noctuidae was the highest (54 species), and for Pterophoridae, Cossidae, Limacodidae, Lasiocampidae, Pieridae and Lycaenidae were the lowest (all with 1 species). The Shannon-Wiener species diversity index (H') and Pielou's evenness (J') of lepidopteran insects first increased and then decreased across these three years, while the Simpson diversity index showed a trend of subtracted-then-added. For molecular-based identification, 67 lepidopteran species within 61 genera in 14 families were identified through DNA barcoding. Neighbor Joining (NJ) analysis showed that conspecific individuals were clustered together and formed monophyletic groups with a high support value, except for Lacanobia contigua (Denis & Schiffermüller, 1775) (Noctuidae: Hadeninae). Sixty-seven morphospecies were classified into various numbers of MOTUs based on ABGD, BINs, GMYC, jMOTU and bPTP (70, 96, 2, 71, and 71, respectively). In Xinjiang wild fruit forests, the family with the largest number of species is Noctuidae, followed by Geometridae, Crambidae, and the remaining families. The highest Shannon diversity index is observed for the family Noctuidae. Our results indicate that the distance-based methods (ABGD and jMOTU) and character-based method (bPTP) outperform GMYC. BINs is inclined to overestimate species diversity compared to other methods.
description: Funding provided by: National Natural Science Foundation of China
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100001809
Award Number: 31772508
description: Diversity indices were analyzed following Subedi et al. (2021). Traditonal morphological methods were used for species identification. Ambiguous morphological identification were assigned through a similarity search against the GenBank public database (https://www.ncbi.nlm.nih.gov/) and BOLD system (Barcode of Life Data System) (http://www.boldsystems.org/) based on DNA barcodes.
Testing the effect of hemolymph from selected insect species on cell viability
Creators: name: Knežić, Teodora
name: Avramov, Miloš
name: Tatić, Vanja
name: Popović, Željko
name: Petrović, Miloš
name: Gadjanski, Ivana
Publisher: name: Zenodo
Year: 2023

description: TESTING THE EFFECT OF HEMOLYMPH FROM SELECTED INSECT SPECIES ON CELL VIABILITY
Teodora Knežić,1 Miloš Avramov,2 Vanja Tatić,2 Željko D. Popović,2 Miloš Petrović,3 Ivana Gadjanski1
1 Center for Biosystems, BioSense Institute, University of Novi Sad; Serbia; 2 Department of Biology and Ecology, Faculty of Sciences, University of Novi Sad; Serbia; 3 Department of Plant and Environmental Protection, Faculty of Agriculture, University of Novi Sad; Serbia
Introduction: Insects have long been an important nutrient source for human consumption worldwide. Given that they are protein-rich, especially their hemolymph, insects represent one of the most promising sustainable solutions to the global problem of protein deficiency due to the growing world population. However, insect proteomes are generally understudied, which is one of the obstacles for insects to be accepted as future food. Therefore, it is very important that insect proteins, as well as hemolymph as their primary source, be well characterized. The first step would be to elaborate their biological functions and potential biotoxicity, so here the effect of hemolymph from Tenebrio molitor and Zophobas morio larvae on MRC-5 cell viability was investigated.
Methods: Hemolymph was collected from T. molitor and Z. morio larvae, hemocytes were removed and the concentration of total hemolymph proteins was determined by Bradford assay. Next, MRC-5 cells were treated with different hemolymph concentrations. Finally, the effect of hemolymph on the viability of MRC-5 cells after 48h was examined by MTT assay.
Results: Obtained results showed that T. molitor hemolymph had no negative effect on MRC-5 cell viability after 48h regardless of concentration, while only the highest concentration of Z. morio hemolymph slightly decreased cell viability after 48h.
Conclusion: Given that all tested concentrations of T. molitor hemolymph, as well as most concentrations of Z. morio hemolymph, had no cytotoxic effect on MRC-5 cells as a model of normometabolic human cells, they could be used in further research as a source of potential alternative proteins.
Key words: insects; hemolymph; cell viability; alternative proteins; future food
Acknowledgements: This study was supported by the Ministry of Science, Technological Development and Innovation of the Republic of Serbia, grant nos. 451-03-47/2023-01/200358, 451-03-47/2023-01/200125 and 451-03-47/2023-01/200117, MSCA-RISE H2020 project IPANEMA grant agreement no. 872662 and European Union's Horizon 2020 research and innovation program under grant agreement no. 739570 (ANTARES).
VALIDATION OF LAMP ASSAY FOR KLEBSIELLA AEROGENES DETECTION IN THREE VEGETABLE SPECIES
Creators: name: Pavlović, Marija
name: Djisalov, Mila
name: Šašić Zorić, Ljiljana
name: Janjušević, Ljiljana
name: Popović, Željko
name: Gadjanski, Ivana
Publisher: name: Zenodo
Year: 2023

description: VALIDATION OF LAMP ASSAY FOR KLEBSIELLA AEROGENES DETECTION IN THREE VEGETABLE SPECIES
Marija Pavlović2, Mila Djisalov1, Ljiljana Šašić Zorić1, Ljiljana Janjušević1, Željko D. Popović2, Ivana Gadjanski1
1 BioSense Institute, University of Novi Sad, Dr Zorana Đinđića 1, 21000 Novi Sad, Serbia; 2 Department of Biology and Ecology, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia
Introduction: Klebsiella aerogenes is a foodborne pathogen that contaminates fruits and vegetables. Detecting it in a timely manner is essential to prevent its transmission through contaminated food sources. In this regard, the LAMP method proved to be a robust, highly sensitive and highly specific method for real-time pathogen detection, and thus method of choice for detection of K. aerogenes.
Methods: We selected three distinct vegetable types (carrot, cucumber, and lettuce) that were artificially contaminated (spiked) with a bacterial suspension containing 1.5 x 109 CFU/mL of K. aerogenes. DNA extraction from the samples was performed using two approaches: Chelex approach for fast extraction, and Plant/Fungi DNA Isolation Kit (Norgen Biotek Corp., Canada) for spin-column extraction. The total DNA extracted from both methods was subsequently diluted to a concentration of 1 ng/μL and used for the LAMP assay. 
Results: The results indicated successful detection of K. aerogenes by LAMP using total DNA from both extraction approaches. DNA isolated with a commercial kit reaches the exponential phase of the reaction approximately five minutes earlier compared to DNA obtained by the Chelex method. This can be related to the fact that fast DNA extracts often contain nucleic acid amplification inhibitors.
Conclusion: The presented research highlights the remarkable potential of the LAMP methodology that can be efficiently combined with fast DNA extraction methods for in-field detection of pathogens.
Key words: LAMP, Klebsiella aerogenes, foodborne pathogens, molecular diagnostics
Acknowledgements: This research was funded by MSCA-RISE H2020 project IPANEMA (grant agreement number 872662) and by the Ministry of Science, Technological Development, and Innovations of the Republic of Serbia (grant agreement number 451-03-47/2023-01/200358).
Additional file 1 of Health-related quality of life in children and adolescents with overweight and obesity: results from the German KIGGS survey
Creators: name: Meixner, Lara
name: Cohrdes, Caroline
name: Schienkiewitz, Anja
name: Mensink, Gert B. M.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1 Table S1. Predicting Health-Related Quality of Life Domains (Social Support & Peers, School Environment) by Children’s and Adolescent’s Weight Status Separately for Girls (n = 936) and Boys (n = 834), While Controlling for Relevant Health Determinants.
Asymptotic solution of the diffusion equation in slender impermeable tubes of revolution. I. The leading-term approximation
Creators: name: Traytak, Sergey D.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The anisotropic 3D equation describing the pointlike particles diffusion in slender impermeable tubes of revolution with cross section smoothly depending on the longitudial coordinate is the object of our study. We use singular perturbations approach to find the rigorous asymptotic expression for the local particles concentration as an expansion in the ratio of the characteristic transversal and longitudial diffusion relaxation times. The corresponding leading-term approximation is a generalization of well-known Fick-Jacobs approximation. This result allowed us to delineate the conditions on temporal and spatial scales under which the Fick-Jacobs approximation is valid. A striking analogy between solution of our problem and the method of inner-outer expansions for low Knudsen numbers gas kinetic theory is established. With the aid of this analogy we clarify the physical and mathematical meaning of the obtained results.
description: 44 pages, 2 figures
Mapping of Topological Quantum Circuits to Physical Hardware
Creators: name: Paler, Alexandru
name: Devitt, Simon J.
name: Nemoto, Kae
name: Polian, Ilia
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Topological quantum computation is a promising technique to achieve large-scale, error-corrected computation. Quantum hardware is used to create a large, 3-dimensional lattice of entangled qubits while performing computation requires strategic measurement in accordance with a topological circuit specification. The specification is a geometric structure that defines encoded information and fault-tolerant operations. The compilation of a topological circuit is one important aspect of programming a quantum computer, another is the mapping of the topological circuit into the operations performed by the hardware. Each qubit has to be controlled, and measurement results are needed to propagate encoded quantum information from input to output. In this work, we introduce an algorithm for mapping an topological circuit to the operations needed by the physical hardware. We determine the control commands for each qubit in the computer and the relevant measurements that are needed to track information as it moves through the circuit.
description: 16 Pages, 8 Figures, to Appear Sci. Rep
New generation of continuous hydrothermal flow synthesis materials for environmental applications
Creators: name: Baragau, Ioan - Alexandru
Publisher: name: London South Bank University
Year: 2021

description: The demands for new materials such as carbonaceous nanomaterials and their nanocomposites that are produced in a more efficient, economical, and environmentally friendly manner, as well as the need to integrate them into applications that address global issues, is a current challenge. The focus of this doctoral research project was to develop faster, cleaner synthetic methods to produce materials with superior physical and chemical properties utilising sustainable and/or renewable precursors, ultimately delivering solutions to challenges in environmental applications and beyond. This was accomplished using a continuous hydrothermal flow synthesis approach. Continuous hydrothermal flow synthesis is an unconventional method that uses supercritical water as a reaction environment, and it was designed for the very fast, continuous flow production of high quality and high quantity nanomaterials, with real-time control over the process parameter (temperature, pressure, precursors concentration, pH, and flow rates). For the first time, by developing and applying CHFS methodologies, carbon quantum dots (CQDs) and nitrogen-doped carbon quantum dots (NCQDs) were synthesized. The CHFS CQDs and NCQDs were produced from biomass-related precursors: glucose and citric acid; the synthetic process can be classified not only as green but sustainable too. The reduction of graphene oxide with a non-corrosive and reusable reducing agent (formic acid) was achieved. The reduced graphene oxide with different oxygen content (17.37 at%, 16.82 at% and 13.3 at%) was synthesised. A new CHFS method to produce nano TiO2 (anatase) has been developed to pioneer the one-pot synthesis of carbonaceous nanocomposites of TiO2 with NCQDs and reduced graphene oxide (rGO). All the materials produced in this study have been characterised and tested in environmental-related applications: a) toxic ions sensing (CQDs, NCQDs) with promising limits of detection for hexavalent chromium (LODCQDs= 3.62 ppm and LODNCQDs=0.365 ppm), b) graphene-related membrane-based water treatment with good performances, and photocatalysis where the TiO2 and its carbonaceous nanocomposites were tested for photodegradation of methylene blue with excellent conversions and rates constants (the best photocatalyst, TiO2-NCQDs-rGO(1), showed a conversion of 93.45% and a rate constant of 25.24 x10-5 s-1). This research project designed and engineered new promising carbonaceous materials, expanding the CHFS portfolio to new frontiers. The as-prepared materials exhibited superior physical, chemical, and morphological characteristics demonstrating their potential for environmental applications and beyond.
Aprison_Figure S1 from The serotonin circuit that coordinates germline proliferation and egg laying with other reproductive functions in Caenorhabditis elegans
Creators: name: Aprison, Erin Z.
name: Dzitoyeva, Svetlana
name: Ruvinsky, Ilya
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Developmental Biology

description: Additional experiments in support of Figures 1A and 2A.
title: КЛИНИКО-ИНСТРУМЕНТАЛЬНЫЕ ПОКАЗАТЕЛИ КОМОРБИДНОЙ СОСУДИСТОЙ ОТЯГОЩЕННОСТИ У БОЛЬНЫХ МУЛЬТИФОКАЛЬНЫМ АТЕРОСКЛЕРОЗОМ
title: CLINICAL AND INSTRUMENTAL INDICATORS OF VASCULAR COMORBIDITY IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS
Creators: name: Хасанов, Азат  Хамитович
name: Давлетшин, Рашит Ахметович
name: Асфандияров, Фэрит Загитович
name: Колчина, Эмма Михайловна
name: Мехдиев, Джамаладдин Исаевич
name: Амирова, Альбина Мухарямовна
Publisher: name: Издательский центр СурГУ
Year: 2019

description: Цель - определение особенностей коморбидной отягощенности у больных с мультифокальным атеросклерозом с учетом гетерогенности клинической симптоматики для определения топики поражения и профилактики заболеваний. Материалы и методы. Методом иерархического анализа категориальных переменных больные были разделены на 3 кластера согласно клинической манифестации атеросклеротического поражения сердца (1-й - 96 человек), головного мозга (2-й - 96 человек) и артерий нижних конечностей (3-й - 96 человек), подтвержденного коронароангиографией, ультразвуковой допплероскопией магистральных артерий головы и нижних конечностей. У всех больных проводили оценку клинического состояния, ЭКГ, ЭХО-КГ. Результаты. У больных 1-го кластера установлено преобладание артериальной гипертензии III стадии и наличие стеноза в бассейне левой сонной артерии > 30 %. Гемодинамически значимый стеноз в бассейне правой общей сонной артерии, наличие атеросклеротической бляшки правой и левой общей сонной артерии преобладали среди больных 3-го кластера.
description: The aim of the study is to identify comorbidity characteristics in patients with multifocal atherosclerosis taking into account the heterogeneity of clinical symptomatology for estimation of disease topography and prevention. Materials and Methods. According to the hierarchical analysis of categorical variables patients are divided up into 3 clusters: cluster 1 (96 patients) - clinical manifestations of atherosclerotic cardiovascular disease; cluster 2 (96 patients) - cerebral atherosclerosis; cluster 3 (96 patients) - lower extremity arterial disease. The diseases are proved at coronary angiography, Doppler ultrasonography of the major artery of the head and lower extremities. Clinical state, electrocardiogram, and echocardiogram in all patients are evaluated. Results. Patients of the cluster 1 are diagnosed with a predominance of stage 3 arterial hypertension and stenosis > 30 % in the left internal carotid artery territory. Hemodynamically significant stenosis in the right common carotid artery territory, atherosclerotic plaques in the right and left common carotid arteries are dominant among patients of the cluster 3.
Additional file 1 of Clinicopathologic characteristics and surgical outcome of synthetic fiber conjunctival granuloma
Creators: name: Chen, Zhang
name: Tianyang Wang
name: Qintuo Pan
name: Zhang, Zhaoliang
name: Zongduan Zhang
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 1. Clinical photographs of 18 patients with synthetic fiber conjunctival granuloma (only for review).
The Astronomical Reach of Fundamental Physics
Creators: name: Burrows, Adam
name: Ostriker, Jeremiah P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Using basic physical arguments, we derive by dimensional and physical analysis the characteristic masses and sizes of important objects in the Universe in terms of just a few fundamental constants. This exercise illustrates the unifying power of physics and the profound connections between the small and the large in the Cosmos we inhabit. We focus on the minimum and maximum masses of normal stars, the corresponding quantities for neutron stars, the maximum mass of a rocky planet, the maximum mass of a white dwarf, and the mass of a typical galaxy. To zeroth order, we show that all these masses can be expressed in terms of either the Planck mass or the Chandrasekar mass, in combination with various dimensionless quantities. With these examples we expose the deep interrelationships imposed by Nature between disparate realms of the Universe and the amazing consequences of the unifying character of physical law.
description: Accepted as a Perspective to the Proceedings of the National Academy of Sciences (PNAS)
Categorification of Pre-Lie Algebras and Solutions of 2-graded Classical Yang-Baxter Equations
Creators: name: Sheng, Yunhe
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Rings and Algebras (math.RA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: In this paper, we introduce the notion of a pre-Lie 2-algebra, which is a categorification of a pre-Lie algebra. We prove that the category of pre-Lie 2-algebras and the category of 2-term pre-Lie$_\infty$-algebras are equivalent. We classify skeletal pre-Lie 2-algebras by the third cohomology of a pre-Lie algebra. We prove that crossed modules of pre-Lie algebras are in one-to-one correspondence with strict pre-Lie 2-algebras. $\mathcal O$-operators on Lie 2-algebras are introduced, which can be used to construct pre-Lie 2-algebras. As an application, we give solutions of 2-graded classical Yang-Baxter equations in some semidirect product Lie 2-algebras.
description: 22 pages
Sphere-plate Casimir interaction in (D+1)-dimensional spacetime
Creators: name: Teo, L. P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we derive the formula for the Casimir interaction energy between a sphere and a plate in $(D+1)$-dimensional Minkowski spacetime. It is assumed that the scalar field satisfies the Dirichlet or Neumann boundary conditions on the sphere and the plate. As in the $D=3$ case, the formula is of TGTG type. One of our main contributions is deriving the translation matrices which express the change of bases between plane waves and spherical waves for general $D$. Using orthogonality of Gegenbauer polynomials, it turns out that the final TGTG formula for the Casimir interaction energy can be simplified to one that is similar to the $D=3$ case. To illustrate the application of the formula, both large separation and small separation asymptotic behaviors of the Casimir interaction energy are computed. The large separation leading term is proportional to $L^{-D+1}$ if the sphere is imposed with Dirichlet boundary condition, and to $L^{-D-1}$ if the sphere is imposed with Neumann boundary condition, where $L$ is distance from the center of the sphere to the plane. For the small separation asymptotic behavior, it is shown that the leading term is equal to the one obtained using proximity force approximation. The next-to-leading order term is also computed using perturbation method. It is shown that when the space dimension $D$ is larger than 5, the next-to-leading order has sign opposite to the leading order term. Moreover, the ratio of the next-to-leading order term to the leading order term is linear in $D$, indicating a larger correction at higher dimensions.
description: 17 pages, 1 figure, 2 tables
Aprison_Table S2 from The serotonin circuit that coordinates germline proliferation and egg laying with other reproductive functions in Caenorhabditis elegans
Creators: name: Aprison, Erin Z.
name: Dzitoyeva, Svetlana
name: Ruvinsky, Ilya
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Developmental Biology

description: List of strains in Figure 2A
Additional file 1 of Large and non-specific somatic disease burdens among ageing, long-term opioid maintenance treatment patients
Creators: name: Medved, David
name: Clausen, Thomas
name: Bukten, Anne
name: Bjørnestad, Ronny
name: Muller, Ashley Elizabeth
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplementary Table 1. Chronic conditions, health care utilization, and satisfaction by gender (NorComt study, Norway, 2012–2016). legend. The subgroup analyses by gender revealed few differences in chronic conditions, treatment received, and satisfaction.
On concentrators and related approximation constants
Creators: name: Bondarenko, A. V.
name: Prymak, A.
name: Radchenko, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: Primary 41A63 (46A10). Secondary 05D40, 05C35

description: Pippenger ([Pippenger, 1977]) showed the existence of $(6m,4m,3m,6)$-concentrator for each positive integer $m$ using a probabilistic method. We generalize his approach and prove existence of $(6m,4m,3m,5.05)$-concentrator (which is no longer regular, but has fewer edges). We apply this result to improve the constant of approximation of almost additive set functions by additive set functions from $44.5$ (established in [Kalton, Roberts, 1983]) to $39$. We show a more direct connection of the latter problem to the Whitney type estimate for approximation of continuous functions on a cube in $\mathbb{R}^d$ by linear functions, and improve the estimate of this Whitney constant from $802$ (proved in [Brudnyi, Kalton, 2000]) to $73$.
A network-patch methodology for adapting agent-based models for directly transmitted disease to mosquito-borne disease
Creators: name: Manore, Carrie A.
name: Hickmann, Kyle S.
name: Hyman, James M.
name: Foppa, Ivo M.
name: Davis, Justin K.
name: Wesson, Dawn M.
name: Mores, Christopher N.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences

description: Mosquito-borne diseases cause significant public health burden, mostly in tropical and sub-tropical regions, and are widely emerging or re-emerging in areas where previously absent. Understanding, predicting, and mitigating the spread of mosquito-borne disease in diverse populations and geographies are ongoing modeling challenges. We propose a hybrid network-patch model for the spread of mosquito-borne pathogens that accounts for the movement of individuals through mosquito habitats and responds to environmental factors such as rainfall and temperature. Our approach extends the capabilities of existing agent-based models for individual movement developed to predict the spread of directly transmitted pathogens in populations. To extend to mosquito-borne disease, agent-based models are coupled with differential equations representing `clouds' of mosquitoes in geographic patches that account for mosquito ecology, including heterogeneity in mosquito density, emergence rates, and extrinsic incubation period. We illustrate the method by adapting an agent-based model for human movement across a network to mosquito-borne disease. We investigated the importance of heterogeneity in mosquito population dynamics and host movement on pathogen transmission, motivating the utility of detailed models of individual behavior. We observed that the total number of infected people is greater in heterogeneous patch models with one high risk patch and high or medium human movement than it would be in a random mixing homogeneous model. Our hybrid agent-based/differential equation model is able to quantify the importance of the heterogeneity in predicting the spread and invasion of mosquito-borne pathogens. Mitigation strategies can be more effective when guided by realistic models created by extending the capabilities of existing agent-based models to include vector-borne diseases.
description: 34 pages, 13 figures
Quantum-Number Exotic Tetraquarks at Large $N_c$ in QCD(AS)
Creators: name: Cohen, Thomas D.
name: Lebed, Richard F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: It is shown that the large $N_c$ limit of QCD with quarks in the two-index antisymmetric color representation [QCD(AS)] has narrow tetraquark states with exotic flavor quantum numbers. They decay into mesons with a width that is parametrically $O(1/N_c^2)$. Tetraquarks with non-exotic quantum numbers mix at leading order with mesons of the same overall quantum numbers. QCD(AS) at $N_c=3$ corresponds to ordinary QCD; its large $N_c$ limit represents an alternative starting point for a $1/N_c$ expansion to the standard one with quarks in the fundamental color representation.
description: 5 pages, 2 .eps figures, ReVTeX
Building Knowledge Graphs for DH Data
Creators: name: Schlögl, Matthias
name: Tuominen, Jouni
Publisher: name: Zenodo
Year: 2023

description: A central outcome of InTaVia is a knowledge graph, which harmonizes and links biographical
data from four prosopographical databases across Europe (FI, NL, AT, SI) and connects
them to related cultural objects from Wikidata and Europeana. For producing the InTaVia
Knowledge Graph the consortium has worked on three major outcomes. The InTaVia Data
Model (IDM-RDF), a CIDOC CRM and Bio CRM based ontology used to model the data in the
triplestore, pipeline components to convert and enrich the data and a Rest API in front of
the triplestore to deliver the data in a simplified and sanitised way to the web application
and interested users.
The presentation will give an overview of this architecture and discuss pros and cons of the
design decisions with regard to other semantic web applications and projects in the field.
On the $\partial\overline{\partial}$-Lemma and Bott-Chern cohomology
Creators: name: Angella, Daniele
name: Tomassini, Adriano
Publisher: name: arXiv
Year: 2014
Subjects: subject: Differential Geometry (math.DG)
subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 32Q99

description: On a compact complex manifold $X$, we prove a Frölicher-type inequality for Bott-Chern cohomology and we show that the equality holds if and only if $X$ satisfies the $\partial\overline{\partial}$-Lemma.
An Emergent Universe with Dark Sector Fields in a Chiral Cosmological Model
Creators: name: Beesham, A.
name: Chervon, S. V.
name: Maharaj, S. D.
name: Kubasov, A. S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider the emergent universe scenario supported by a chiral cosmological model with two interacting dark sector fields: phantom and canonical. We investigate the general properties of the evolution of the kinetic and potential energies as well as the development of the equation of state with time. We present three models based on asymptotic solutions and investigate the phantom part of the potential and chiral metric components. The exact solution corresponding to a global emergent universe scenario, starting from the infinite past and evolving to the infinite future, has been obtained for the first time for a chiral cosmological model. The behavior of the chiral metric components responsible for the kinetic interaction between the phantom and canonical scalar fields has been analyzed as well.
description: 16 pages, To appear in Quantum Matter
Revisiting surface-integral formulations for one-nucleon transfers to bound and resonance states
Creators: name: Escher, J. E.
name: Thompson, I. J.
name: Arbanas, G.
name: Elster, Ch.
name: Eremenko, V.
name: Hlophe, L.
name: Nunes, F. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: One-nucleon transfer reactions, in particular (d,p) reactions, have played a central role in nuclear structure studies for many decades. Present theoretical descriptions of the underlying reaction mechanisms are insufficient for addressing the challenges and opportunities that are opening up with new radioactive beam facilities. We investigate a theoretical approach that was proposed recently to address shortcomings in the description of transfers to resonance states. The method builds on ideas from the very successful R-matrix theory; in particular it uses a similar separation of the parameter space into interior and exterior regions, and introduces a parameterization that can be related to physical observables, which, in principle, makes it possible to extract meaningful spectroscopic information from experiments. We carry out calculations, for a selection of isotopes and energies, to test the usefulness of the new approach.
description: 6 figures (total of 24 figure panels)
Additional file 1 of Oral rehydration solution coverage in under 5 children with diarrhea: a tri-country, subnational, cross-sectional comparative analysis of two demographic health surveys cycles
Creators: name: Gona, Philimon N.
name: Gona, Clara M.
name: Chikwasha, Vasco
name: Haruzivishe, Clara
name: Sowmya R. Rao
name: Chabila C. Mapoma
Publisher: name: figshare
Year: 2020
Subjects: Medicine
Biotechnology
Cancer
Science Policy
Computational Biology

description: Additional file 1: Supplemental Table 1. Coverage of ORS by location, and mother’s characteristics, 2007/2010 (1st period). Supplemental Table 2. Coverage of ORS by location, and mother’s characteristics, 2013/2016 (2nd Period).
PSYCHOLOGICAL FEATURES OF TRAINING EMPLOYEES OF EDUCATIONAL ORGANIZATIONS FOR INNOVATIVE SERVICE
Creators: name: Biysekova, Sarbinaz
Publisher: name: Zenodo
Year: 2023

description: Training employees of educational organizations for innovative service requires understanding and addressing the psychological features that influence their mindset and attitudes towards innovation. This includes cultivating a growth mindset, fostering psychological safety, developing creativity and problem-solving skills, promoting adaptability and flexibility, and addressing psychological barriers to change. By focusing on these psychological aspects, organizations can empower their employees to embrace innovation and drive positive change in the educational context.
Supplementary Material (specific Methods, FIgures and Tables) from Warming signals in temperate reef communities following more than a decade of ecological stability
Creators: name: Soler, G. A.
name: Edgar, G. J.
name: Barrett, N. S.
name: Stuart-Smith, R. D.
name: Oh, E.
name: Cooper, A.
name: Ridgway, K. R.
name: Ling, S. D.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Methods specifying calculations of Thermal Mid Points (MPs) and Linear Models used to determine the effect of Sea Surface Temperature (SST) in the metrics of interest (richness, biomass, abundance, macroalgae cover). Figures with SST by regions through time. Multi-decadal trends of biomass of herbivore fish, biomass of planktivore fish, abundance of herbivore macroinvertebrates, abundance of invertivore macroinvertebrates, abundance of planktivore macroinvertebrate and biomass of urchins in each region of Tasmania. Draftman's plots of correlations between metrics and covariates. List of sites surveyed around Tasmania. List of fish, invertebrates and macroalgae by region for each period. Statistical tables for PERMANOVA and linear model outputs. Fish, macroinvertebrate and macroalgae relative change against their Thermal MP.
Additional file 1 of Therapeutic efficacy of umbilical cord-derived stem cells for diabetes mellitus: a meta-analysis study
Creators: name: Kassem, Dina H.
name: Kamal, Mohamed M.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer

description: Additional file 1 : Supplementary Table S1. PRISMA checklist.
Testing the Titius-Bode law predictions for Kepler multi-planet systems
Creators: name: Huang, Chelsea X.
name: Bakos, Gáspár Á.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We use three and half years of Kepler Long Cadence data to search for the 97 predicted planets of Bovaird & Lineweaver (2013) in 56 of the multi-planet systems, based on a general Titius-Bode relation. Our search yields null results in the majority of systems. We detect five planetary candidates around their predicted periods. We also find an additional transit signal beyond those predicted in these systems. We discuss the possibility that the remaining predicted planets are not detected in the Kepler data due to their non-coplanarity or small sizes. We find that the detection rate is beyond the lower boundary of the expected number of detections, which indicates that the prediction power of the TB relation in general extra solar planetary systems is questionable. Our analysis of the distribution of the adjacent period ratios of the systems suggests that the general Titius-Bode relation may over-predict the presence of planet pairs near the 3:2 resonance.
description: Accepted by MNRAS
Supplementary_Material from Biological control interventions reduce pest abundance and crop damage while maintaining natural enemies in sub-Saharan Africa: a meta-analysis
Creators: name: Ratto, Fabrizia
name: Bruce, Toby
name: Chipabika, Gilson
name: Mwamakamba, Sithembile
name: Mkandawire, Rachel
name: Khan, Zeyaur
name: Mkindi, Angela
name: Pittchar, Jimmy
name: Sallu, Susannah M.
name: Whitfield, Stephen
name: Wilson, Kenneth
name: Sait, Steven M.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Literature search string;ROSES diagram; list of grey literature and electronic databases; articles included in meta-analysis;Fullen plots; Egger's test;Fail Safe numbers; Influential case diagnostics
Additional file 1 of Process data of allogeneic ex vivo-expanded ABCB5+ mesenchymal stromal cells for human use: off-the-shelf GMP-manufactured donor-independent ATMP
Creators: name: Ballikaya, Seda
name: Sadeghi, Samar
name: Niebergall-Roth, Elke
name: Nimtz, Laura
name: Frindert, Jens
name: Norrick, Alexandra
name: Stemler, Nicole
name: Bauer, Nicole
name: Rosche, Yvonne
name: Kratzenberg, Vanessa
name: Pieper, Julia
name: Ficek, Tina
name: Frank, Markus H.
name: Ganss, Christoph
name: Esterlechner, Jasmina
name: Kluth, Mark A.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 1 : Table S1. Tests and specifications for drug substance batch and final drug product release. Table S2. Mean live cell count per ABCB5+ cell isolate by donor. Table S3 Results from drug substance batch release testing by donor.
Experimental validation of the electric sail concept
Creators: name:  S. MAZOUFFRE
name:   U. WELLER
Publisher: name: Proceedings of the Aerospace Europe Conference - EUCASS - CEAS - 2023
Year: 2023
Subjects: ELECTRIC SAIL
INTERPLANETARY

description: The electric sail is a type of propellant-less propulsion system that relies on the solar wind dynamic pressure to create thrust and move a spacecraft. In this contribution, we present recent experimental results on ion deflection by an electric sail. The sail is here represented by a thin tungsten wire polarized to high positive or negative voltages. A low-power Hall thruster generates a quasi-neutral ion beam that mimics the solar wind. Various electrostatic probes are placed downstream of the sail to analyse the plasma disturbance created when the voltage is applied and ramped up. Ions are deflected whatever the applied voltage, the impact being more marked for large values. Experiments therefore indirectly demonstrate momentum from the beam is imparted to the wire, the core principle of an electric sail.
A precision study of the fine tuning in the DiracNMSSM
Creators: name: Kaminska, Anna
name: Ross, Graham G.
name: Schmidt-Hoberg, Kai
name: Staub, Florian
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recently the DiracNMSSM has been proposed as a possible solution to reduce the fine tuning in supersymmetry. We determine the degree of fine tuning needed in the DiracNMSSM with and without non-universal gaugino masses and compare it with the fine tuning in the GNMSSM. To apply reasonable cuts on the allowed parameter regions we perform a precise calculation of the Higgs mass. In addition, we include the limits from direct SUSY searches and dark matter abundance. We find that both models are comparable in terms of fine tuning, with the minimal fine tuning in the GNMSSM slightly smaller.
description: 20 pages + appendices, 10 figures
Metabolizable Bi2Se3 Nanoplates: Biodistribution, Toxicity, and Uses for Cancer Radiation Therapy and Imaging
Creators: name: Zhang, Xiao-Dong
name: Chen, Jie
name: Min, Yuho
name: Park, Gyeong Bae
name: Shen, Xiu
name: Song, Sha-Sha
name: Sun, Yuan-Ming
name: Wang, Hao
name: Long, Wei
name: Xie, Jianping
name: Gao, Kai
name: Zhang, Lianfeng
name: Fan, Saijun
name: Fan, Feiyue
name: Jeong, Unyong
Publisher: name: arXiv
Year: 2013
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: Bi, a high atom number element, has a high photoelectric absorption coefficient, and Se element has anticancer activity. Hence, their compound chalcogenide (Bi2Se3) deserves a thorough investigation for biomedical applications. This study reveals that Bi2Se3 nanoplates (54 nm wide) protected with poly(vinylpyrollidone) (PVP) are biocompatible and have low toxicity even at a high dose of 20 mg/kg in mice. This conclusion was made through the studies on the biodistribution and 90-day long term in vivo clearance of the nanoplates. Liver and spleen were dominant organs for the nanoplates accumulation which was mainly due to RES absorption, but 93 % the nanoplates were cleared after 90 days treatment. Concentrations of Bi and Se in tumor tissue continuously increased until 72 h after intraperitoneal injection into mice. Such selective accumulation of Bi was utilized to enhance the contrast of X-ray CT images. The Bi elements concentrated in a tumor led to damage on the tumor cells when exposed to gamma radiation. Growth of the tumor significantly delayed and stopped after 16 days after the tumor was treated with the Bi2Se3 nanoplates and radiation. This work clearly shows that the Bi2Se3 nanoplates may be used for cancer radiation therapy and CT imaging. They deserve further studies for biological and medical applications.
description: 32 pages, 12 figures. Advanced Functional Materials, 2014
INHERITANCE AND VARIABILITY OF SOME MORPHOLOGICAL CHARACTERS IN ECOLOGICALLY AND GEOGRAPHICALLY DISTANT G' OZA HYBRIDS
Creators: name: Raupova, Iroda
Publisher: name: Zenodo
Year: 2023

description: In this article, we aim to study the genetic patterns and variability of selected morpho-economic traits in ecologically-geographically distant cotton hybrids. Through a review of existing literature and research, we highlight the importance of exploring and exploiting the genetic potential of these hybrids to improve cotton yield and sustainability. The results of such studies are expected to help develop new breeding strategies and select superior cotton varieties suitable for different environmental conditions.
Supplementary Methods and Results from Cannabinoid receptor 2 evolutionary gene loss makes parrots more susceptible to neuroinflammation
Creators: name: Divín, Daniel
name: Goméz Samblas, Mercedes
name: Kuttiyarthu Veetil, Nithya
name: Voukali, Eleni
name: Świderská, Zuzana
name: Krajzingrová, Tereza
name: Těšický, Martin
name: Beneš, Vladimír
name: Elleder, Daniel
name: Bartoš, Oldřich
name: Vinkler, Michal
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine

description: In vertebrates, cannabinoids modulate neuroimmune interactions through two cannabinoid receptors (CNRs) conservatively expressed in the brain (CNR1, syn. CB1) and in the periphery (CNR2, syn. CB2). Our comparative genomic analysis indicates several evolutionary losses in the CNR2 gene that is involved in immune regulation. Notably, we show that the CNR2 gene pseudogenised in all parrots (Psittaciformes). This CNR2 gene loss occurred due to chromosomal rearrangements. Our positive selection analysis suggests the absence of any specific molecular adaptations in parrot CNR1 that would compensate for the CNR2 loss in the modulation of the neuroimmune interactions. Using transcriptomic data from the brains of birds with experimentally induced sterile inflammation we highlight possible functional effects of such a CNR2 gene loss. We compare the expression patterns of CNR and neuroinflammatory markers in CNR2-deficient parrots (represented by the budgerigar, Melopsittacus undulatus and five other parrot species) with CNR2-intact passerines (represented by the zebra finch, Taeniopygia guttata). Unlike in passerines, stimulation with lipopolysaccharide resulted in the parrots in neuroinflammation linked with a significant upregulation of expression in proinflammatory cytokines (including interleukin 1 beta, IL1B and IL6) in the brain. Our results indicate the functional importance of the CNR2 gene loss for increased sensitivity to brain inflammation.