cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Engineering Polydopamine as a Novel Drug Delivery Nanocarrier
Creators: name: Batul, Rahila
Publisher: name: Swinburne
Year: 2024

description: This thesis states the research work based on polydopamine nanostructures (nanoparticles and nanocoatings) to be used as drug delivery nanocarriers. Polydopamine nanostructures were in situ loaded with variable antimicrobials to present their long-term drug release, hence exhibiting antimicrobial effects over an extended period. These approaches could overcome the side-effects of the drug by providing an on-demand pH-dependent drug release at the targeted site, hence can maintain the drug efficacy and improve the patience compliance.
title: Per- and polyfluoroalkyl substances in blood plasma - Results of the German Environmental Survey for children and adolescents 2014-2017 (GerES V)
title: Per- and polyfluoroalkyl substances in blood plasma - Results of the German Environmental Survey for children and adolescents 2014-2017 (GerES V)
titleType: AlternativeTitle
Creators: name: Conrad, André
name: Duffek, Anja
name: Kolossa-Gehring, Marike
name: Lange, Rosa
name: Rucic, Enrico
name: Schulte, Christoph
name: Wellmitz, Jörg
Publisher: name: My University
Year: 2020
Subjects: Human-Biomonitoring

description: The 5th cycle of the German Environmental Survey (GerES V) investigated the internal human exposure of children and adolescents aged 3-17 years in Germany to per- and polyfluoroalkyl substances (PFAS). The fieldwork of the population-representative GerES V was performed from 2014 to 2017. In total, 1109 blood plasma samples were analysed for 12 PFAS including perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and perfluorohexane sulfonic acid (PFHxS). PFOS was quantified in all and PFOA in almost all samples, demonstrating ubiquitous exposure. The highest geometric mean concentrations measured were 2.49 ng/mL for PFOS, followed by PFOA (1.12 ng/mL) and PFHxS (0.36 ng/mL), while concentrations of other PFAS were found in much lower concentrations. The 95th percentile levels of PFOS and PFOA were 6.00 and 3.24 ng/mL, respectively. The results document a still considerable exposure of the young generation to the phased out chemicals PFOS and PFOA. The observed exposure levels vary substantially between individuals and might be due to different multiple sources. The relative contribution of various exposure parameters such as diet or the specific use of consumer products need to be further explored. Although additional investigations on the time trend of human exposure are warranted, GerES V underlines the need for an effective and sustainable regulation of PFAS as a whole. Source: © 2020 Elsevier GmbH
Stochastic analysis of robot-safety systems.
Creators: name: Fashandi, Ali R. M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Engineering, Mechanical.

description: Robot population is increasing at an incredible pace. Over the last fifteen years, robot population grew from 30,000 in 1983, to the forecasted 820,000 by the end of 1998. Their infancy period has come to an end and they are not just being used in the automotive industry or required to perform simple tasks. They are now being employed in various sectors of industry and handle much more complex operations. Increased robot system complexity and their critical applications utilization have led to various reliability and safety problems. In 1982, the Machine Tool Trade Associations guidelines stated that a working robot can be a potential hazard to personnel under certain circumstances. The need for robot system safety was highlighted by a 10-million dollar lawsuit awarded to the family of a worker killed by an industrial robot in 1983. This study presents a detailed introductory aspect of robot safety, an identification of the most appropriate robot systems reliability and safety assessment techniques, and probabilistic modelling of robot-safety systems. The domain of the probabilistic models include: a stochastic analysis of a system containing one robot with n-redundant safety units, a stochastic analysis of a system composed of n-redundant robots with one safety unit, and an availability analysis of robot systems susceptible to common-cause failure. The primal intent of the analyses is to develop generalized and numerical expressions relating to the performance indices for robot systems operating with or without the safety unit. Generalized models are introduced and generalized expressions including reliability, time-dependent availability, steady-state availability, and mean time to failure (MTTF) are developed. In order to assess performance indices, some special cases of the generalized models are presented resulting in the formation of numerical values. Robot system performance indices are determined by means of the Markovian and non-Markovian methods. The method of supplementary variables and the device of stages are used to deal with the non-Markovian models. Various failed system repair time distributions (i.e., exponential, gamma, Weibull, Rayleigh, and log-normal distributions) have been considered to obtain generalized steady state availability expressions. Markov method is utilized in models where failure and repair rates are assumed constant. With the aid of Laplace transforms, a system of first-order differential equations are solved and generalized reliability and MTTF expressions are developed.
Immersive virtual reality technology as a tool to enhance children's cognition and learning
Creators: name: Araiza Alba, Paola
Publisher: name: Swinburne
Year: 2024

description: Children are consumers of a wide variety of media technologies, including TV, video games, touchscreen and more recently, virtual reality (VR). Historically, every time new technology is introduced in our lives, it comes with concerns and doubts about the potential, benefits, and effects on children. While VR technology has been predominately used with adults, some pilot studies have established the value of using VR in different disciplines related to its use with children; however, these are not abundant. This research body focuses on investigating the most evidence-based applications of immersive VR with children and the effects of this technology on children's cognition and learning.
title: Telerradiología de urgencias: Nuestra experiencia en cuatro años.
Creators: name: Esteve Krauel, Pablo
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Management
subject: Computer applications

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
-EVALUAR EL SISTEMA DE TELERADIOLOGÍA DE URGENCIAS REALIZADO EN NUESTRO CENTRO. -DESCRIBIR LAS VENTAJAS E INCONVENIENTES DEL...
Die (Re)produktion von Weiblichkeitskonstruktionen durch Werbung am Beispiel der Videospots Zalandos
Creators: name: Fritzsche, Ricarda
Publisher: name: Medien- und Informationszentrum, Leuphana Universität Lüneburg
Year: 2021
Subjects: classificationCode: 330
subject: 330 Wirtschaft

description: Die Bachelorarbeit untersucht mithilfe der Film- und Fernsehanalyse nach Lothar Mikos den Werbespot "Banküberfall" der Werbeagentur Jung von Matt für den deutschen Online-Versandhandel Zalando in Hinblick auf die Darstellungsweise von Weiblichkeit. Das Material wird daraufhin analysiert, welche Weiblichkeitskonstruktionen es liefert. Es soll erforscht werden, auf welche Praktiken, Mechanismen und Formen der Geschlechterherstellung zurückgegriffen wird, um Weiblichkeit als binäre Struktur zu inszenieren. Der Spot wird dabei im Kontext des vorausgehenden theoretischen Teils analysiert. Dieser stützt sich auf Judith Butlers Annahmen zum prozessualen Sein und Werden von Weiblichkeit. Es wird die These aufgestellt, dass der Zalando-Werbespot, indem er geschlechtsspezifisch agierende Figuren nutzt und Stereotype abbildet, die bereits vorgefertigten Bilder des Frauseins, sowie eine binäre Geschlechterordnung (re)produziert. Diese Annahme wird jedoch nach Lothar Mikos Methode ebenso auf Brüche und Ambivalenzen untersucht. Das Ziel der Arbeit mündet darin aufzuzeigen, durch welche diskursiven, verbalen, sowie nonverbalen Verfahren Weiblichkeit erst als übergreifendes Gesellschaftskonstrukt und später als konkretes Konstrukt im Werbespot hergestellt wird. Das Aufzeigen einer greifbaren Weiblichkeitsvorstellung in der Reklame soll exemplarisch dafür stehen, wie standhaft sich bestimmte Vorstellungen über die Frau auch heutzutage noch in der Gesellschaft, den Medien und der Werbung halten.
title: Correlación Clínica de las Variantes Anatómicas Óseas del Carpo: Hallazgos en TC y RM.
Creators: name: García González, Claudia Nelly
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Tissue characterisation
subject: Diagnostic procedure
subject: Computer Applications-3D
subject: CT
subject: MR
subject: Musculoskeletal system
subject: Extremities

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Las variaciones en la anatomía ósea de las estructuras de la muñeca se diagnostican fácilmente mediante métodos de imagen. Los objetivos del presente estudio son: Evaluar las variaciones en la estructura ósea del carpo y su diagnóstico...
Supplementary document for Demonstration of tailorable and durable substrate-engraved antireflective metasurfaces for high power laser applications - 4559144.pdf
Creators: name: Ray, Nathan
name: Yoo, Jae Hyuck
name: Nguyen, Hoang
name: Johnson, Michael
name: Elhadj, Selim
name: Baxamusa, Salmaan
name: Feigenbaum, Eyal
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores
Creators: name: Chen, Lawrence M.
name: Yao, Nelson
name: Garg, Elika
name: Zhu, Yuecai
name: Nguyen, Thao T. T.
name: Pokhvisneva, Irina
name: Hari Dass, Shantala A.
name: Unternaehrer, Eva
name: Gaudreau, Hélène
name: Forest, Marie
name: McEwen, Lisa M.
name: MacIsaac, Julia L.
name: Kobor, Michael S. (Geneticist)
name: Greenwood, Celia M. T.
name: Silveira, Patricia P.
name: Meaney, Michael J.
name: O’Donnell, Kieran J.
Publisher: name: BioMed Central
Year: 2018

description: Background: Polygenic risk scores (PRS) describe the genomic contribution to complex phenotypes and consistently account for a larger proportion of variance in outcome than single nucleotide polymorphisms (SNPs) alone. However, there is little consensus on the optimal data input for generating PRS, and existing approaches largely preclude the use of imputed posterior probabilities and strand-ambiguous SNPs i.e., A/T or C/G polymorphisms. Our ability to predict complex traits that arise from the additive effects of a large number of SNPs would likely benefit from a more inclusive approach. Results: We developed PRS-on-Spark (PRSoS), a software implemented in Apache Spark and Python that accommodates different data inputs and strand-ambiguous SNPs to calculate PRS. We compared performance between PRSoS and an existing software (PRSice v1.25) for generating PRS for major depressive disorder using a community cohort (N = 264). We found PRSoS to perform faster than PRSice v1.25 when PRS were generated for a large number of SNPs (~ 17 million SNPs; t = 42.865, p = 5.43E-04). We also show that the use of imputed posterior probabilities and the inclusion of strand-ambiguous SNPs increase the proportion of variance explained by a PRS for major depressive disorder (from 4.3% to 4.8%). Conclusions: PRSoS provides the user with the ability to generate PRS using an inclusive and efficient approach that considers a larger number of SNPs than conventional approaches. We show that a PRS for major depressive disorder that includes strand-ambiguous SNPs, calculated using PRSoS, accounts for the largest proportion of variance in symptoms of depression in a community cohort, demonstrating the utility of this approach. The availability of this software will help users develop more informative PRS for a variety of complex phenotypes.
title: Gradación de los astrocitomas mediante histogramas de diferentes parámetros de perfusión tisular obtenidos con RM
Creators: name: Revert Ventura, Antonio J.
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
La proliferación vascular es uno de los descriptores histológicos que se usan para clasificar los tumores gliales en grados de malignidad.
Los estudios de perfusión por RM basados en la inyección de un medio de contraste exógeno proporcionan...
Les agressions sexuelles en milieu carcéral : une perspective des prisonniers canadiens.
Creators: name: Guérette, Micheline Roxane.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Sociology, Criminology and Penology.

description: Cette thèse veut faire l'étude d'un groupe d'anciens prisonniers afin de connaître et d'analyser leur point de vue concernant les agressions sexuelles en milieu carcéral, l'importance du problème et les conséquences pour les acteurs, dans le but d'améliorer la situation des prisonniers et de sensibiliser le public et la communauté scientifique à cette réalité souvent négligée. Cette étude offrira aussi une perspective canadienne sur les agressions sexuelles entre prisonniers. Afin d'obtenir l'opinion des prisonniers sur les agressions sexuelles, nous avons interrogé six ancien(ne)s prisonnier(ère)s ayant purgé au moins une sentence dans un établissement carcéral canadien dans une ou plusieurs provinces. Ces entrevues de type non-directif portaient sur la sexualité des prisonniers et les agressions sexuelles en prison. À la lumière de ces entrevues, les agressions sexuelles sont une forme de violence auxquelles doivent faire face les prisonniers. Elles sont présentes dans les établissements carcéraux canadiens quoique moins fréquentes que les autres formes d'agressions. Toutefois, si nous incluons les échanges sexuels qui se produisent dans les relations wolf -jeune et les paiements des dettes accumulées, l'importance de cette réalité peut être plus grande due à l'ambiguïté du consentement qui est fortement influencé par le besoin de se protéger et de survivre. (Abstract shortened by UMI.)
Reducing occupational sitting: Workers' perspectives on participation in a multi-component intervention
Creators: name: Hadgraft, Nyssa
name: Willenberg, Lisa
name: LaMontagne, Anthony D.
name: Malkoski, Keti
name: Dunstan, David W.
name: Healy, Genevieve N.
name: Moodie, Marj
name: Eakin, Elizabeth G.
name: Owen, Neville
name: Lawler, Sheleigh P.
Publisher: name: Swinburne
Year: 2024

description: Background: Office workers spend much of their time sitting, which is now understood to be a risk factor for several chronic diseases. This qualitative study examined participants' perspectives following their involvement in a cluster randomised controlled trial of a multi-component intervention targeting prolonged workplace sitting (Stand Up Victoria). The intervention incorporated a sit-stand workstation, individual health coaching and organisational support strategies. The aim of the study was to explore the acceptability of the intervention, barriers and facilitators to reducing workplace sitting, and perceived effects of the intervention on workplace culture, productivity and health-related outcomes. Methods: Semi-structured interviews (n = 21 participants) and two focus groups (n = 7) were conducted with intervention participants at the conclusion of the 12 month trial and thematic analysis was used to analyse the data. Questions covered intervention acceptability, overall impact, barriers and facilitators to reducing workplace sitting, and perceived impact on productivity and workplace culture. Results: Overall, participants had positive intervention experiences, perceiving that reductions in workplace sitting were associated with improved health and well-being with limited negative impact on work performance. While sit-stand workstations appeared to be the primary drivers of change, workstation design and limited suitability of standing for some job tasks and situations were perceived as barriers to their use. Social support from team leaders and other participants was perceived to facilitate behavioural changes and a shift in norms towards increased acceptance of standing in the workplace. Conclusions: Multi-component interventions to reduce workplace sitting, incorporating sit-stand workstations, are acceptable and feasible; however, supportive social and environmental conditions are required to support participant engagement. Best practice approaches to reduce workplace sitting should address the multiple levels of influence on behaviour, including factors that may act as barriers to behavioural change.
Supplementary document for Demonstration of tailorable and durable substrate-engraved antireflective metasurfaces for high power laser applications - 4559144.pdf
Creators: name: Ray, Nathan
name: Yoo, Jae Hyuck
name: Nguyen, Hoang
name: Johnson, Michael
name: Elhadj, Selim
name: Baxamusa, Salmaan
name: Feigenbaum, Eyal
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplemental Document
Exploring Medical Expert Testimony and its Contribution to Miscarriages of Justice An Examination of the Flawed Pathological Evidence of Dr Charles Smith
Creators: name: Thom, Ashley C
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Law.
subject: Sociology, Criminology and Penology.

description: Wrongful convictions have garnered recent increased attention in Canada, but specific concern with the use of medical expert evidence in criminal trials is especially timely. With the recent Inquiry into Pediatric Forensic Pathology in Ontario, it has become clear that flawed medical expert evidence can have devastating effects on individuals and criminal trials. The theoretical framework of social constructionism was used in a cross-case pattern analysis to provide a foundation for examining the problematic expert testimony of Dr. Charles Smith in eight cases of unexplained child death. The findings suggest that Dr. Smith's expert evidence was not adequately evaluated at the gate of admissibility, and may have been evaluated by internalized judgments rather than direct assessments of that evidence. The results indicate a combination of contributing factors of Dr. Smith's flawed expert evidence and the subsequent miscarriages of justice, as Dr. Smith's flaws were overlooked and his testimony accepted uncritically.
title: Caracterización de las lesiones adrenales mediante TC y RM: todo lo que un radiológo general debe conocer.
Creators: name: Quintana Valcarcel, Paula
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: CT
subject: MR
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
1.
Revisar la embriología y anatomía de las glándulas adrenales. 2. Mostrar las características radiológicas de un amplio espectro de patologías frecuentes y no frecuentes que afectan a las glándulas adrenales,mediante diferentes técnicas de...
The Experiences and Sibling Relationships of Adult Children of Holocaust Survivors
Creators: name: Krauskopf, Irene
Publisher: name: Swinburne
Year: 2024

description: Dr Krauskopf’s research investigated the impact of trauma transmission in Holocaust survivor families from the perspective of siblings and the role of sibling relationships. Her research demonstrated that the burden of parental Holocaust history does not fall equally on siblings in the same family with some siblings experiencing negative effects while others learned messages of resilience from their parents. The research also uniquely identified that supportive sibling relationships can ameliorate the effects of parental trauma. These novel findings extend the understanding of Holocaust survivor families and have important implications for future research on families impacted by trauma.
title: Correlación radio-patológica en el diagnóstico de lesiones pulmonares mediante PAAF guiada por TC
Creators: name: Canales Lachén, Elena
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Lung
subject: CT
subject: Puncture
subject: Diagnostic procedure

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Evaluar el papel de la punción aspiración con aguja fina (PAAF) guiada por tomografía computarizada (TC) en el diagnóstico de las lesiones pulmonares. Analizar su validez diagnóstica como patrón de referencia,
así como sus ventajas y...
Efficient estimation of the probability of extreme cell delays
Creators: name: Lamothe, Gilles
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Mathematics.

description: We wish to estimate the probability of extreme cell delays for a particular virtual connection (VC) or virtual path (VP) in an Asynchronous Transfer Mode (ATM) network. Since extreme cell delays are rare events we cannot efficiently estimate the probability of extreme cell delays using crude Monte-Carlo methods. We increase (exponentially twist) the workload of a related Markov additive chain, which we call the encumbrance, and use the A-cycle sampling technique to analyse switches with finite buffers multiplexing cells from Bernoulli interrupted sources with constant bit rate during bursts.
Supplementary document for Electro-optic coherent interface for ultra-sensitive time-domain cavity quantum electrodynamics experiments from microwaves to terahertz frequencies - 4560740.pdf
Creators: name: Benea-Chelmus, Ileana-Cristina
name: Salamin, Yannick
name: Settembrini, Francesca Fabiana
name: Fedoryshyn, Yuriy
name: Heni, Wolfgang
name: Elder, Delwin
name: Dalton, Larry
name: Leuthold, Juerg
name: Faist, Jérôme
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplementary material
Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses
Creators: name: Twardziok, M.
name: Meierhofer, D.
name: Boerno, S.
name: Timmermann, B.
name: Jaeger, S.
name: Boral, Senguel
name: Eggert, A.
name: Delebinski, C. I.
name: Seifert, G.
Publisher: name: Freie Universität Berlin
Year: 2017
Subjects: subject: Childhood cancer
subject: Alternative medicine
subject: Phytotherapy
subject: ER stress
subject: Oleanolic acid
subject: Betulinic acid
subject: MAPK
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background The hydrophobic triterpenes, oleanolic and betulinic acid as well as the hydrophilic mistletoe lectins and viscotoxins possess anticancer properties. They do all occur in combination in European mistletoe (Viscum album L.). Commercial Viscum album L. extracts are aqueous, excluding the insoluble triterpenes. We have previously shown that mistletoe lectins and triterpene acids are effective against Ewing sarcoma in vitro, ex vivo and in vivo. Methods We recreated a total mistletoe effect (viscumTT) by combining an aqueous extract (viscum) and a triterpene extract (TT) solubilised with cyclodextrins and analysed the effects of viscumTT and the single extracts on TC-71 Ewing sarcoma cells in vitro by transcriptomic and proteomic profiling. Results Treatment with the extracts strongly impacted Ewing sarcoma cell gene and protein expression. Apoptosis-associated and stress-activated genes were upregulated, proteasomal protein abundance enhanced and ribosomal and spliceosomal proteins downregulated. The mechanism of action of viscum, TT and viscumTT in TC-71 and MHH-ES-1 cells suggests the involvement of the unfolded protein response. While viscum and viscumTT extract treatment indicate response to oxidative stress and activation of stress-mediated MAPK signalling, TT extract treatment suggests the involvement of TLR signalling and autophagy. Conclusions Since the combinatory extract viscumTT exerts highly effective pro-apoptotic effects on Ewing sarcoma cells in vitro, this phytopolychemotherapy could be a promising adjuvant therapeutic option for paediatric patients with Ewing sarcoma.
Mapping The Text
Creators: name: Isherwood, Timothy
name: Kendall, Judy
Publisher: name: University of Salford
Year: 2019
Subjects: classificationCode: 470101
subject: Communication studies
classificationCode: 360201
subject: Creative writing (incl. scriptwriting)
classificationCode: 360699
subject: Visual arts not elsewhere classified
classificationCode: 360199
subject: Art history, theory and criticism not elsewhere classified
classificationCode: 330399
subject: Design not elsewhere classified

description: This essay and self-directed case study focuses on the impact of the typeface in which written texts are set. It argues for the potential that can be realised from foregrounding typefaces in the creative process through typographic-poetic collaborations. By selecting poems to suit typefaces or creating poems for typefaces, poetry can benefit creatively from a typeface's materiality.
title: Patient perspectives on the use of digital medical devices and sensitive health data for AI-driven personalized medicine in Parkinson
Creators: name: Ivana Paccoud
name: Mayca Marín Valero
name: Laura Carrasco Marín
name: Noémi Bontridder
name: Alzhraa Ibrahim
name: Jürgen Winkler
name: Messaline Fomo
name: Stefano Sapienza
name: Fouad Khoury
name: Jean-Christophe Corvol
name: Holger Fröhlich
name: Jochen Klucken
Publisher: name: LCSB
Year: 2024

description: Introduction: Parkinson’s Disease (PD) affects around 8.5 million people currently with numbers expected to rise to 12 million by 2040. PD is characterized by fluctuating motor and non-motor symptoms demanding accurate monitoring. Recent advancements in digital medical devices (DMDs) like wearables and AI offer promise in addressing these needs. However, the successful implementation of DMDs in healthcare relies on patients' willingness to adopt and engage with these digital tools.
Methods: To understand patient perspectives in individuals with PD, a cross-sectional study was conducted as part of the EU-wide DIGIPD project across France, Spain, and Germany. Multidisciplinary teams including neurodegenerative clinics and patient organizations conducted surveys focusing on (i) sociodemographic information, (ii) use of DMDs (iii) acceptance of using health data (iv) preferences for the DMDs use. We used descriptive statistics to understand the use of DMDs and patient preferences and logistic regression models to identify predictors of willingness to use DMDs and to share health data through DMDs.
Results: In total 333 individuals with PD participated in the study. Findings revealed a high willingness to use DMDs (90.3% ) and share personal health data (97.4%,) however this differed across sociodemographic groups and was more notable among older age groups (under 65=17.9% vs over 75= 39.29%, p=0.001) and those with higher education levels less willing to accept such use of data (university level = 78.6% vs 21.43% with secondary level, p=0.025).  Providing Instruction on the use and receiving feedback on the results of the data collection significantly increased the willingness to use DMDs (OR=3.57, 95% CI= 1.44-8.89) and reports (OR=3.77, 95% CI= 1.01-14.12), respectively.
Conclusion: The study emphasizes the importance of considering patient perspectives for the effective deployment of digital technologies, especially for older and more advanced disease-stage patients who stand to benefit the most.
The Relationship Between Immunity and Aging in D.Melanogaster
Creators: name: Silva, Ashley
Publisher: name: Zenodo
Year: 2024
Subjects: D.melanogaster
aging
immunity
experimental evolution

description: Human populations have variations in lifespan, aging, and immunity and generally experience worsened immune defense at old ages. Understanding the relationship between aging and immune defense is facilitated through model organism research, including the fruit fly Drosophila melanogaster. In D.melanogaster, some aspects of immunity improve with age, but others get worse. For instance, studies depict that the process of undergoing selection for improved immunity directly favors the activation of canonical immune defense genes, which directly target pathogens but can sometimes have detrimental effects on lifespan. These genes are classified as antagonistic. Meanwhile, in studies that depict a selection for improved longevity in pathogen-free environments, the evolved longevity is associated with enhanced overall robustness and stress resistance and improvements in immune function without directly targeting classical immune-specific genes. These genes are classified as cooperative and improve the host condition broadly, allowing the host to better tolerate pathogenic infection.
Supplementary Material from A first vocal repertoire characterisation of long-finned pilot whales (Globicephala melas) in the Mediterranean Sea: a machine learning approach
Creators: name: Poupard, Marion
name: Best, Paul
name: Morgan, Jay Paul
name: Pavan, Gianni
name: Glotin, Hervé
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: Figure
Pastoral care of Eastern Catholic faithful residing outside their historical territory with particular reference to the United States and Canada
Creators: name: Oonnonny, George N
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Religion, General.
subject: Law.

description: During the past two centuries, millions of people belonging to Eastern Christian traditions, due to a variety of reasons, have found themselves uprooted from their native soil and planted in Western Europe, Canada, United States, Latin America and Australia. Five fundamental, but intrinsically related, issues constitute the core of our study of pastoral care of Eastern Catholics living in the diaspora. The first issue we consider is the origins of Eastern Catholic Churches, in order to identify and understand the root causes of the problem. If the Eastern and Western (Latin) traditions were identical, then there would have been no reason for raising the question in the first place. The second issue concerns the actual pastoral problems directly affecting those faithful who are displaced from their native territories and find themselves in the diaspora. The third issue is related to the source of the right of Eastern Catholics to proper pastoral care flowing from their legitimate ascription to a Church sui iuris. The fourth issue involves the proper authorities who have the primary obligation to provide pastoral care for the faithful. It includes the highly debated question of the jurisdiction of the patriarch or archieparch over their faithful who live outside their historical territory. The fifth issue concerns appropriate pastoral approaches to problems faced today by Eastern Catholics in the diaspora. Our study is divided into five chapters corresponding to the five issues mentioned above. Thus, the first chapter deals with the historical origins of the Eastern Catholic Churches. In the second and third chapters we examine the current pastoral problems of the Eastern Catholic faithful in the diaspora and their right to appropriate pastoral care in virtue of their ascription to a particular sui iuris Church. Historical evidence indicates that the Church has always demonstrated its pastoral solicitude toward migrants and displaced people. This is evident in the Church's documents and papal teachings. An analysis of these ecclesiastical documents is the thrust of the fourth chapter. In the final chapter we address some issues of practical and pastoral importance related to Eastern Catholics living in the diaspora. Also included in this final chapter is an analysis of the results of a questionnaire we sent out to selected arch/dioceses in the United States and Canada. (Abstract shortened by UMI.)
Supplementary document for Electro-optic coherent interface for ultra-sensitive time-domain cavity quantum electrodynamics experiments from microwaves to terahertz frequencies - 4560740.pdf
Creators: name: Benea-Chelmus, Ileana-Cristina
name: Salamin, Yannick
name: Settembrini, Francesca Fabiana
name: Fedoryshyn, Yuriy
name: Heni, Wolfgang
name: Elder, Delwin
name: Dalton, Larry
name: Leuthold, Juerg
name: Faist, Jérôme
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: supplementary material
Cancer-testis antigen cyclin A1 is broadly expressed in ovarian cancer and is associated with prolonged time to tumor progression after platinum-based therapy
Creators: name: Arsenic, Ruza
name: Braicu, Elena Ilona
name: Letsch, Anne
name: Dietel, Manfred
name: Sehouli, Jalid
name: Keilholz, Ulrich
name: Ochsenreither, Sebastian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: Immunotherapy
subject: Ovarian cancer
subject: Cytotoxic T-lymphocytes
subject: Cyclin A1
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Background Cyclin A1 is essential for male gametopoiesis. In acute myeloid leukemia, it acts as a leukemia-associated antigen. Cyclin A1 expression has been reported in several epithelial malignancies, including testicular, endometrial, and epithelial ovarian cancer (EOC). We analyzed Cyclin A1 expression in EOC and its correlation with clinical features to evaluate Cyclin A1 as a T-cell target in EOC. Methods Cyclin A1 mRNA expression in EOC and healthy tissues was quantified by microarray analysis and quantitative real-time PCR (qRT-PCR). Protein expression in clinical samples was assessed by immunohistochemistry (IHC) and was correlated to clinical features. Results Cyclin A1 protein was homogeneously expressed in 43 of 62 grade 3 tumor samples and in 1 of 10 grade 2 specimens (p
title: Lesiones quísticas pélvicas no ováricas: Qué tenemos que decir los radiólogos
Creators: name: Rubio Hervás, Carlos
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: Genital / Reproductive system female
subject: Pelvis
subject: Ultrasound
subject: CT
subject: MR
subject: Cysts

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir e ilustrar los hallazgos de imagen asociados a lesiones quísticas pélvicas no...
Die Risiken des Klimawandels für Deutschland
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2022
Subjects: subject: Klimaänderung
subject: Klimarisiko
subject: Anpassung an den Klimawandel
subject: Deutsche Anpassungsstrategie an den Klimawandel
subject: Klimawandel
subject: Klimaanpassung
subject: Klima | Energie

description: Diese Broschüre enthält die wichtigsten Ergebnisse der Klimawirkungs- und Risikoanalyse 2021 für Deutschland (KWRA), ergänzt um die Schlussfolgerungen der Interministerielle Arbeitsgruppe "Anpassung an den Klimawandel" (IMA-A). Die KWRA zeigt, bei welchen Auswirkungen des Klimawandels und wo besondere Risiken, Möglichkeiten zur Anpassung und Handlungserfordernisse bestehen. Die IMA-A sieht in der KWRA eine wichtige Grundlage für die Weiterentwicklung der Deutschen Anpassungsstrategie, besonders für die nächsten Aktionspläne der Bundesregierung, und für das Anpassungshandeln anderer Akteure. Die Schlussfolgerungen sollten daher für das Anpassungshandeln aller Akteure in Deutschland handlungsleitend sein. Quelle: www.umweltbundesamt.de
description: Diese Broschüre enthält die wichtigsten Ergebnisse der Klimawirkungs- und Risikoanalyse 2021 für Deutschland (KWRA), ergänzt um die Schlussfolgerungen der Interministerielle Arbeitsgruppe „Anpassung an den Klimawandel“ (IMA-A). Die KWRA zeigt, bei welchen Auswirkungen des Klimawandels und wo besondere Risiken, Möglichkeiten zur Anpassung und Handlungserfordernisse bestehen. Die IMA-A sieht in der KWRA eine wichtige Grundlage für die Weiterentwicklung der Deutschen ⁠Anpassungsstrategie⁠, besonders für die nächsten Aktionspläne der Bundesregierung, und für das Anpassungshandeln anderer Akteure. Die Schlussfolgerungen sollten daher für das Anpassungshandeln aller Akteure in Deutschland handlungsleitend sein.
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis
Creators: name: Herold, Tobias
name: Schneider, Stephanie
name: Metzeler, Klaus H.
name: Neumann, Martin
name: Baldus, Claudia D.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Philadelphia-like B-cell precursor acute lymphoblastic leukemia (Ph-like ALL) is characterized by distinct genetic alterations and inferior prognosis in children and younger adults. The purpose of this study was a genetic and clinical characterization of Ph-like ALL in adults. Twenty-six (13%) of 207 adult patients (median age: 42 years) with B-cell precursor ALL (BCP-ALL) were classified as having Ph-like ALL using gene expression profiling. The frequency of Ph-like ALL was 27% among 95 BCP-ALL patients negative for BCR- ABL1 and KMT2A-rearrangements. IGH-CRLF2 rearrangements (6/16; P=0.002) and mutations in JAK2 (7/16; P<0.001) were found exclusively in the Ph-like ALL subgroup. Clinical and outcome analyses were restricted to patients treated in German Multicenter Study Group for Adult ALL (GMALL) trials 06/99 and 07/03 (n=107). The complete remission rate was 100% among both Ph-like ALL patients (n=19) and the “remaining BCP-ALL” cases (n=40), i.e. patients negative for BCR-ABL1 and KMT2A-rearrangements and the Ph-like subtype. Significantly fewer Ph-like ALL patients reached molecular complete remission (33% versus 79%; P=0.02) and had a lower probability of continuous complete remission (26% versus 60%; P=0.03) and overall survival (22% versus 64%; P=0.006) at 5 years compared to the remaining BCP-ALL patients. The profile of genetic lesions in adults with Ph-like ALL, including older adults, resembles that of pediatric Ph-like ALL and differs from the profile in the remaining BCP-ALL. Our study is the first to demonstrate that Ph-like ALL is associated with inferior outcomes in intensively treated older adult patients. Ph-like adult ALL should be recognized as a distinct, high-risk entity and further research on improved diagnostic and therapeutic approaches is needed. (NCT00199056, NCT00198991)
Water safety plan
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2014
Subjects: Trinkwasser
Risikomanagement
Wassergüte
Wasserversorgung

description: Sicheres Trinkwasser in hinreichender Quantität und annehmbarer Qualität ist eine zentrale Voraussetzung für gute Gesundheit, wirtschaftliche Entwicklung und nachhaltiges Auskommen der Familien in ländlichen Gemeinden. Durch planmäßiges Vorgehen kann in kleineren Versorgungssystemen sicheres Trinkwasser auf wirksamste Weise gewährleistet werden.
Dieser für den Einsatz vor Ort gedachte Leitfaden führt die in Landdistrikten an der Wasserversorgung beteiligten Menschen Schritt für Schritt mit Hilfe einer Reihe erprobter Modelle so in die Wassersicherheitsplanung ein, dass sie eigene derartige Pläne erstellen können.
Der Leitfaden wendet sich teils an die für den Betrieb und die Abwicklung der Wasserversorgung zuständigen Menschen in den ländlichen Gemeinden, teils an Bedienstete der örtlichen Gesundheitsämter und Wasserwerke, welche für die Sicherung der Trinkwasserqualität zuständig sind, sowie an nichtstaatliche Organisationen, welche die Sicherheit des Trinkwassers in den Landgemeinden unterstützen.
© www.euro.who.int
Supplementary Material from A first vocal repertoire characterisation of long-finned pilot whales (Globicephala melas) in the Mediterranean Sea: a machine learning approach
Creators: name: Poupard, Marion
name: Best, Paul
name: Morgan, Jay Paul
name: Pavan, Gianni
name: Glotin, HervÃ©
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: Figure
Supplementary document for Surface Plasmon Assisted Control of Hot-Electron Relaxation Time - 4563360.pdf
Creators: name: Memarzadeh, Sarvenaz
name: Kim, Jongbum
name: Aytac, Yigit
name: Munday, Jeremy
name: Murphy, Thomas
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental material_Adding new figure_Fig,S4
Testing Predictive Software Systems and A Case Study of Oil Drilling
Creators: name: Luu, Quang-Hung
Publisher: name: Swinburne
Year: 2024

description: Having a wide range of applications from weather forecasts to self-driving vehicles, predictive software systems are developed to predict unknowns or future events. Their uncertainties and inaccuracies pose a grand challenge in testing due to the missing of a mechanism to validate their correctness. Metamorphic testing technique is used to derive effective metamorphic relations for testing three commonly-used systems which rely on multiple linear regression, neural networks and probability distribution. In addition to successful tests with random data, a case study is conducted with real-life oil drilling data where predictive models were constructed and well tested.
Maximal exercise capacity, peripheral muscle strength, sleep quality, and quality of life in adult patients with stable asthma
Creators: name: ÖZDEMİR, Furkan
name: GÜÇLÜ, Meral BOŞNAK
name: Prof., Hanım Eda GÖKTAŞ
name: Prof., İ. Kıvılcım OĞUZÜLGEN
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: The prevalence of asthma is increasing gradually worldwide. The pathophysiological process of asthma causes some alterations in the respiratory system and decreases oxygen-carbon dioxide exchange and respiration volume. These alterations may affect maximal exercise capacity, peripheral muscle strength, sleep quality, and disease-specific quality of life but have yet to be comprehensively investigated. To compare maximal exercise capacity, pulmonary function, peripheral muscle strength, dyspnea, sleep quality, and quality of life in adult patients with asthma, healthy controls were aimed. Forty-one adult stable asthmatic patients (GINA I-III) and 41 healthy subjects were compared. Exercise capacity (cardiopulmonary exercise test [CPET]), pulmonary function (spirometry), peripheral muscle strength (dynamometer), dyspnea (modified Medical Research Council [mMRC] dyspnea scale), quality of life (Asthma Quality of Life Questionnaire [AQLQ]) and sleep quality (Pittsburgh Sleep Quality Index [PSQI]) were evaluated. Peak VO2, VO2kg, MET, VE, HR, %VE, %HR, VCO2 parameters of CPET, FVC, FEV1, FEF25-75%, and FEV1/FVC and quadriceps femoris, shoulder abductors, and hand grip muscles strength were significantly decreased in patients with asthma (p < 0.05). MMRC dyspnea scale score was increased, and AQLQ and PSQI scores decreased in asthma patients (p < 0.05). Cardiac and pulmonary system responses to peak exercise worsened, and maximal exercise capacity and peripheral muscle strength decreased in adult patients with stable asthma. In addition, dyspnea during daily activities increases, and quality of life and sleep quality are impaired. A variety of exercise training that would benefit asthmatic patients' outcomes should be investigated.
Supplementary document for Surface Plasmon Assisted Control of Hot-Electron Relaxation Time - 4563360.pdf
Creators: name: Memarzadeh, Sarvenaz
name: Kim, Jongbum
name: Aytac, Yigit
name: Munday, Jeremy
name: Murphy, Thomas
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplemental material_Adding new figure_Fig,S4
Mineralogy and geochemistry of the Murdock Creek intrusion, Kirkland Lake, Ontario.
Creators: name: Rowins, Stephen Michael.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Geochemistry.

description: The Murdock Creek intrusion, immediately southwest of Kirkland Lake, Ontario, in the southern part of the Abitibi belt, is a member of a suite of late Archean ($\approx$2680 Ma) syenitic intrusions located within and adjacent to the Kirkland Lake-Larder Lake fault zone (KLF), which host virtually all of the gold mineralization in the Kirkland Lake camp. An early crystallizing mafic margin consisting of clinopyroxenite, meladiorite, melamonzodiorite, and melasyenite encloses an extensive felsic core of alkali-feldspar syenite. A coeval hornblendite unit with lamprophyric affinities, intrudes throughout the pluton and most closely approximates the mantel-derived liquids which differentiated to produce the suite of syenitic intrusions and possibly potassic alkaline extrusive rocks of the Timiskaming Group. The intrinsically oxidized nature of the pluton suggests a genetic link with gold mineralization in the Kirkland Lake camp. (Abstract shortened by UMI.)
Statistical Analysis of a Laboratory Study About the Effects of Bisphenol A on the Reproduction of the Ramshorn snail Marisa cornuarietis (Mesogastropoda: Ampullariidae)
Creators: name: Ratte, Hans Toni
Publisher: name: My University
Year: 2015
Subjects: subject: Bisphenol A
subject: snails
subject: statistical analysis
subject: Chemikalien
subject: Chemicals

description: This report provides the results of a statistical analysis of an experiment with Marisa cornu-arietis (Prosobranchia), the subtropical Ramshorn snail, which was performed during the EU Project "ComprendoŁ. This project aimed at studying the possible impact of endocrine dis-rupters mainly on invertebrate species. Exposure experiments with Bisphenol A (BPA) were performed as semistatic renewal systems under food surplus.
Quelle: http://www.umweltbundesamt.de/
description: This report provides the results of a statistical analysis of an experiment with Marisa cornu-arietis (Prosobranchia), the subtropical Ramshorn snail, which was performed during the EU Project “Comprendo”. This project aimed at studying the possible impact of endocrine dis-rupters mainly on invertebrate species. Exposure experiments with Bisphenol A (BPA) were performed as semistatic renewal systems under food surplus.
Propagation of transients in dispersive dielectric media.
Creators: name: Bui, Man Duc.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, Electronics and Electrical.

description: Propagation of transient electromagnetic fields in dispersive dielectric media is studied. The dielectric medium is assumed to be linear, isotropic, and homogeneous and is described by the Debye model. Incident fields are assumed to be TEM plane wave pulses. The dielectric can assume the form of infinite half space or infinite circular cylinder; either of which may be homogeneous or stratified. The electric fields induced in the dielectric are calculated from Time Domain Maxwell's equations using Finite Difference Time Domain method. The results of this investigation can be used for geophysical probing, subsurface communication and for investigating possible biological effects of pulsed electromagnetic fields.