cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: A practical approach to blinded sample size re-estimation in a randomized trial with a survival endpoint
Creators: name: Pfirrmann, Markus
name: Ziegler, Anette-Gabriele
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: clinical trial
subject: survival analysis
subject: sample size re-estimation
subject: 610 Medical sciences; Medicine

description: Background: In the Fr1da trial (ClinicalTrials.gov identifier: NCT04039945), trial numbers were based on oral insulin halving the exponentially distributed hazard of the events dysglycemia and diabetes as compared with placebo. After recruitment of 163 children, a blinded sample size re-estimation [for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
title: Analyzing propensity score methods on randomized controlled clinical trials
Creators: name: Dieckmann, Daliah
name: Götte, Heiko
name: Jahn, Antje
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Propensity score methods are widely used for analyzing treatment effects in non-randomized controlled trials and observational studies. They account only for observable confounder via analysis. In contrast to that randomized trials account for observable and unobservable confounder via design,[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Δημόσιο χρέος και τεχνική αποτελεσματικότητα:
Creators: name: Πενλίογλου, Γρηγόριος Αχιλλέα
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Δημόσιο χρέος
Τεχνική αποτελεσματικότητα
Περιβάλλουσα ανάλυση δεδομένων
Public debt
Technical efficiency
Data envelopment analysis

description: Η παρούσα διατριβή διερευνά τις επιπτώσεις του δημοσίου χρέους στην τεχνική αποτελεσματικότητα. Η έρευνα αφορά την ομάδα 25 χωρών μελών του ΟΟΣΑ, για τα έτη 1990-2009. Πηγές των δεδομένων αποτελούν οι βάσεις του ΔΝΤ, οι Δείκτες της Παγκόσμιας Τράπεζας, ο ΟΟΣΑ και δεδομένα από τη βάση Penn World Tables. Η εμπειρική ανάλυση αποτελείται από δύο στάδια. Αρχικά, εκτιμάται η προσανατολισμένη προς τις εκροές τεχνική αποτελεσματικότητα, μέσω της Περιβάλλουσας Ανάλυσης Δεδομένων (DEA), υπό την υπόθεση των μεταβλητών αποδόσεων κλίμακας του ορίου παραγωγής, το οποίο χρησιμοποιεί την εργασία και το μετοχικό κεφάλαιο για την παραγωγή ΑΕΠ. Στην συνέχεια η εμπειρική ανάλυση πραγματεύεται την εκτίμηση των επιπτώσεων του δημόσιου χρέους στην τεχνική αποτελεσματικότητα, με τη χρήση της παλινδρόμησης εκτίμησης υπό σταθερές επιδράσεις. Επιπρόσθετα, μια σειρά από μεταβλητές ελέγχου, όπως οι κρατικές δαπάνες, η συνολική επένδυση και το άνοιγμα της οικονομίας, προστίθενται ώστε να εξασφαλιστεί η αξιοπιστία των εκτιμώμενων επιπτώσεων του δημοσίου χρέους στην τεχνική αποτελεσματικότητα. Συνολικά, τα αποτελέσματα δείχνουν ότι το δημόσιο χρέος έχει μια σταθερά αρνητική επίδραση στην τεχνική αποτελεσματικότητα, ακόμη και όταν οι μεταβλητές ελέγχου λαμβάνονται υπόψη.
description: The present thesis attempts to investigate the impact of public debt on technical efficiency. The research concerns a panel of 25 OECD member countries, for the years 1990-2009. The utilized data are obtained from the databases of IMF, World Bank Indicators, OECD and Extended Penn World Tables. The empirical analysis consists of two stages. Firstly, the output oriented technical efficiency is estimated using Data Envelopment Analysis (DEA), whilst assuming that the production frontier, which utilizes labor and capital stock to produce GDP, exhibits variable returns to scale. The analysis then proceeds with the estimation of the impact of public debt on the technical efficiency, by using fixed effects regression estimation. Additionally, a series of control variables such as government spending, total investment and economy openness are added to ensure the robustness of the estimated impact of public debt on technical efficiency. Overall the results indicate that public debt has a persistent negative influence on technical efficiency even when the control variables impact is taken into account.
title: Modeling Multi-Species Distributions in Ecology – an Application of Multivariate Conditional Transformation Models
Creators: name: Barbanti, Luisa
name: Hothorn, Torsten
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: multi-species distributions
subject: multivariate regression
subject: Gaussian copula
subject: most likely transformations
subject: 610 Medical sciences; Medicine

description: Background: Tools for modelling multi-species distributions are of great interest in ecology. The reasons for this are twofold: first, they allow for both a marginal interpretation which provides information about the distribution one species at a time. Secondly, they allow for a joint interpretation,[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Τυπολογία της Ιστορικής Αφήγησης: Ανάλυση του Λόγου των φοιτητών για την Κατοχή και τον Εμφύλιο:
Creators: name: Μουκούλη, Αλίκη Νικολάου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Ανάλυση Λόγου
Κατοχή-Εμφύλιος
Τυπολογία Rusen
Discourse Analysis
Occupation-Civil War
Rusen Typology

description: Αρχικά, καταγράφονται οι σχέσεις ανάμεσα στη γλώσσα και την Ιστορία όπως αυτές παρουσιάζονται στην ελληνική και ξενόγλωσση βιβλιογραφία. Στη συνέχεια γίνεται αναφορά του ιστορικού πλαισίου, που αφορά στα γεγονότα της Κατοχής και του Εμφύλιου πολέμου. Παρουσιάζονται όλες οι λεπτομέρειες που σχετίζονται με την ερευνητική διαδικασία, καθώς και λεπτομερείς πληροφορίες σχετικά με τη διαδικασία των συνεντεύξεων. Ακόμα, αναλύονται τα κριτήρια βάσει των οποίων επιλέχθηκε η μη δομημένη συνέντευξη ως η καταλληλότερη μέθοδος για τη συλλογή των ποιοτικών δεδομένων. Τέλος, εξετάζεται ο τρόπος με τον οποίο τα αποτελέσματα της ανάλυσης βρίσκουν εφαρμογή στην τυπολογία του Rüsen.
description: At first, recorded the relationship between language and History as presented in greek and foreign bibliography. Then, we presented the historical context, relating the events of Occupation and Civil War. We analyzed all details related to the research process as well as detailed information about the interview process. Furthermore, we analyzed the criteria for selecting the semi-structured interview as the most appropriate method for collecting qualitative data. Finally, we examined the way in which the results of the analysis can be applied to the typology of Rüsen.
Two-spin entanglement distribution near factorized states
Creators: name: Baroni, Fabrizio
name: Fubini, Andrea
name: Tognetti, Valerio
name: Verrucchi, Paola
Publisher: name: arXiv
Year: 2007
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the two-spin entanglement distribution along the infinite $S=1/2$ chain described by the XY model in a transverse field; closed analytical expressions are derived for the one-tangle and the concurrences $C_r$, $r$ being the distance between the two possibly entangled spins, for values of the Hamiltonian parameters close to those corresponding to factorized ground states. The total amount of entanglement, the fraction of such entanglement which is stored in pairwise entanglement, and the way such fraction distributes along the chain is discussed, with attention focused on the dependence on the anisotropy of the exchange interaction. Near factorization a characteristic length-scale naturally emerges in the system, which is specifically related with entanglement properties and diverges at the critical point of the fully isotropic model. In general, we find that anisotropy rule a complex behavior of the entanglement properties, which results in the fact that more isotropic models, despite being characterized by a larger amount of total entanglement, present a smaller fraction of pairwise entanglement: the latter, in turn, is more evenly distributed along the chain, to the extent that, in the fully isotropic model at the critical field, the concurrences do not depend on $r$.
description: 14 pages, 6 figures. Final version
title: Simultaneous estimation in Cox proportional hazards model with measurement errors
Creators: name: Chernova, Oksana
name: Kukush, Alexander
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: Cox proportional hazards model
subject: measurement errors
subject: simultaneous estimation of baseline hazard rate and regression parameter
subject: 610 Medical sciences; Medicine

description: Background: The Cox proportional hazards (PH) model is a regression model that can be used in medical research, engineering, finance or insurance for investigating the association between the survival time (the so-called lifetime) of an object and predictor variables. In practice, some covariates could[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Exploring patterns of histone modifications and binding proteins to identify cis-regulatory modules (CRMs) driving the restricted gene expression in dorsal cells of D. melanogaster embryos
Creators: name: Dominguez, Calixto
name: Medina, David
name: Cambiazo, Veronica
name: Perez-Acle, Tomás
name: Holmes, David S
Publisher: name: F1000Research
Year: 2015

description: The primary DNA sequence encodes the regulatory program for the patterning in multicellular organisms. However epigenetic modifications, including histone modifications can modulate the physical access to this program, which is driven by cis-regulatory modules (CRMs) in a temporal-space manner. Genome wide explorations with specific histone modification antibodies at different developmental stage in D. melanogaster have been modelled by numerical representation, which are been associated with functional states. In order to disclose the chromatin states that represent regions with enriched regulatory functions we used a learning algorithm based on multivariate hidden Markov model (HMM).

The dorsal patterning in Drosophila is controlled by an extracellular gradient of the morphogen Decapentlaplegic (Dpp). Dpp signal is transduced to the nucleus by the transcription factors, Mad/Medea. The transcriptional effectors exert their regulation in a graded-manner eliciting at least three threshold responses: high, intermediate and low. We are interested to know whether the patterns on the chromatin are feasible features to specify the CRMs temporal-space restriction. For doing so, we modeled the chromatin states considering 31 genomic marks retrieved from the repository site of the Modencode project. Separate ChIP-chip data from Mad and Medea as well as DNA accessibility data were used to identify the proper model for representing the CRMs chromatin states.

A 14 state model was obtained which largely recovered the set of known CRMs. Remarkably, the genomic segments for the state 4 allowed the identification of the subset of CRMs that drive the gene expression at the embryos dorsal cells. Additionally, 3 putative CRMs were analysed by in situ hybridisation in transgenic reporter lines, which recapitulated the endogenous restricted dorsal expression for genes controlled by the Dpp pathway.
title: Bootstrap approaches for nonparametric factorial repeated measures designs with missing data
Creators: name: Amro, Lubna
name: Pauly, Markus
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Repeated measure designs and split plot plans are widely employed in scientific and medical research. The analysis of such designs is typically based on MANOVA models, requiring complete data, and certain assumption on the underlying parametric distribution such as normality or covariance matrix homogeneity.[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
A Bayesian tensor factorization method to predict drug response in cancer cell lines
Creators: name: Lazar, Nathan
name: Gonen, Mehmet
name: Carbone, Lucia
name: McWeeney, Shannon
name: Margolin, Adam
name: Sonmez, Kemal
Publisher: name: F1000Research
Year: 2015

description: Precision oncology aims to improve cancer patient outcomes by identifying the putative networks that drive a given patient's tumor and attacking these drivers with combinations of targeted therapies. Cell line screening panels give information on how specific tumors may respond to drugs by measuring the growth of tumor cells after exposure to compounds at varying doses in a high-throughput manner. By combining information from these panels with ‘omic profiles of cell lines as well as structural and target information on drugs we can build models to predict response and gain insight into the mechanisms governing response.

Our method decomposes a central three-dimensional tensor encoding the responses of breast cancer cell lines treated with various drugs at 10 doses into latent factors representing characteristics of the cell lines and compounds. By reconstructing the central tensor object from these latent factors, we predict full dose response curves for missing cell line-drug combinations and extrapolate to unseen cell lines and drugs. The use of Bayesian sparsity-inducing priors while training the model allows for the automatic determination of the most informative cell line and drug features. Our method predicts responses at each dose, circumventing issues that arise from using summary measures of drug response. Lastly, by incorporating all of the data into one model, we are able to leverage information from each cell line and drug for the prediction of the others and examine relationships between cell line and drug features.
Η σύμβαση οργανωμένου ταξιδιού σύμφωνα με το π.δ. 339/1996:
Creators: name: Κωνσταντινίδου, Ανατολή Βύρωνα
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: ταξίδι
διοργανωτής
καταναλωτής
organized tours
tour operator
consumer

description: Σκοπός της διατριβής ήταν η μελέτη της σύμβασης οργανωμένου ταξιδιού, η οποία στο ελληνικό δίκαιο ρυθμίζεται από το π.δ. 339/1996. Εξετάστηκαν οι απαραίτητες προϋποθέσεις που πρέπει να συντρέχουν για να υπάρχει οργανωμένο ταξίδι, τα συμβαλλόμενα μέρη (καταναλωτής και διοργανωτής ή/και πωλητής) και επιπλέον τα πρόσωπα που σχετίζονται με την παροχή του οργανωμένου ταξιδιού. Επίσης, εκτέθηκαν οι υποχρεώσεις του διοργανωτή οργανωμένου ταξιδιού αφενός για παροχή αυξημένου επιπέδου πληροφόρησης προς τον αντισυμβαλλόμενό του - καταναλωτή από το προσυμβατικό στάδιο έως το στάδιο κατάρτισης της σύμβασης και αφετέρου για ασφάλιση της επαγγελματικής αστικής ευθύνης της επιχείρησής του έναντι του κινδύνου μη εκπλήρωσης και πλημμελούς εκπλήρωσης της σύμβασης και του κινδύνου αφερεγγυότητας ή πτώχευσης της επιχείρησής του. Ένα άλλο θέμα που αναπτύχθηκε εκτενώς ήταν οι αξιώσεις του καταναλωτή στις περιπτώσεις ανώμαλης εξέλιξης της ενοχής, δηλαδή σε περίπτωση καταγγελίας, ματαίωσης ή πλημμελούς εκπλήρωσης του ταξιδιού. Τέλος, έγινε μία αντιπαραβολή του π.δ. 339/1996 και του Ν. 2251/1994 για την προστασία του καταναλωτή, όπως επίσης και της έννοιας του καταναλωτή που περιέχεται αντίστοιχα στα δύο νομοθετήματα. Σε όλα τα στάδια της διατριβής έγιναν συνεχείς σχετικές αναφορές σε νομολογία τόσο του Δικαστηρίου της Ευρωπαϊκής Ένωσης, όσο και εθνικών δικαστηρίων προς το σκοπό αποσαφήνισης εννοιών και υπόδειξής της πρακτικής διάστασής τους.
description: The aim of the present thesis was the study of organized tours, which are regulated in the greek law by the presidential decree 339/1996. We examined the required conditions that have to subserve, in order to exist an organized tour, the contracting parties (consumer and tour operator or/and package salesman) and moreover the people that are relevant to the provision of this. We also displayed the tour operator’s obligations about the provision of high level information towards his counterparty-consumer since the pre-contractual stage till the moment the contract is signed and also about his professional responsibility’s insurance against the danger of contract’s unfulfillment and incorrect fulfillment or the danger of his company’s insolvency or bankruptcy. Another topic, which was extensively analyzed in the present thesis was the consumer’s claims in case of abnormal evolution of the provision (for example cases of complaint, cancel or incorrect fulfillment). Finally, we have made a comparison between the presidential decree 339/1996 and the Law 2251/1994 about the consumer’s protection, as also the meanings of “consumer” that is included in both laws, that are referred above. Through the present thesis successive relevant references to the jurisprudence of both Court of Justice of the European Union and national courts were presented, in order to clarify the basic meanings and indicate their practical dimension.
Valaha-tanya: a multifunctional agroforestry organic farm in Hungary - Valaha-tanya: wielofunkcyjne gospodarstwo ekologiczne stosujące rozwiązania rolno-leśne na Węgrzech
Creators: name: Vityi, Andrea
name: Kulcsár, Balázs
Publisher: name: Zenodo
Year: 2018
Subjects: organic farm
orchard
wood pasture
biodiversity

description: Gospodarze Valaha-tanya prezentują dobry przykład połączenia rozwiązań rolno-leśnych z permakulturą i uprawą ekologiczną w zrównoważony system. Zakładając i zarządzając tym złożonym gospodarstwem jedynie przy pomocy własnych środków, właściciele zdobyli niesamowite doświadczenie, którym chętnie dzielą się z rolnikami zainteresowanymi wprowadzeniem podobnych rozwiązań.
title: The significance function and confidence valleys for holistic depiction of inference on a parameter
Creators: name: Franklin, Jeremy
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: null hypothesis significance test
subject: confidence interval
subject: inference
subject: p-value function
subject: 610 Medical sciences; Medicine

description: Background: Warning against mis- and over-interpretation of null hypothesis significance testing and the p-value, especially the dichotomisation of results as ‘significant’ or ‘non-significant’, have long been expressed and long remained unheeded. Based on previous suggestions[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Sheep as forest managers – Management of young forest stands by grazing sheep - Owce jako zarządcy lasu – wypas owiec a gospodarka młodymi drzewostanami
Creators: name: Herder, Michael Den
name: Paulo, Joana Amaral
Publisher: name: Zenodo
Year: 2019
Subjects: forest grazing
wood pasture
sheep
wypas w lesie
zadrzewione pastwiska
owce

description: W krajobrazie europejskim owce występują dość licznie, często hodowane są w celach ochrony przyrody lub zarządzania krajobrazem. Artykuł zwraca uwagę na to zagadnienie, omawiając przykłady oraz zagęszczenie hodowli, będące istotnymi czynnikami w zarządzaniu tymi terenami.
title: From baseline data to outcomes: are artificial intelligence based models really competitive?
Creators: name: Sacchetto, Lidia
name: Koechert, Karl
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Background: In trials a huge amount of clinical information is routinely collected per subject, consuming time and resources. Only a small fraction of these data is used in standard analyses, typically for stratification and regulatory assessment purposes. The popularity of Big Data and Artificial Intelligence[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
title: Beta-Binomial Models for Meta-Analysis with Binary Outcomes: Variations, Extensions, and Additional Insights from Econometrics
Creators: name: Mathes, Tim
name: Kuß, Oliver
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: Meta-analysis
subject: beta-binomial models
subject: econometrics
subject: simulation
subject: 610 Medical sciences; Medicine

description: The beta-binomial model has been proven a valuable statistical model for the meta-analysis of binary outcomes, especially in challenging situations with a low number of studies or events or even both. We present two variations of the model for meta-analysis, namely a “common-beta” and [for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
The regulation of intracellular calcium in cultured hippocampal neurons and the influence of calcium buffers
Creators: name: Abdel-Hamid, Khaled Mohammed
Publisher: name: University of British Columbia
Year: 2009

description: Excessive activation of the major neurotransmitter glutamate receptors has been blamed as a causative mechanism in a large number of neuro-pathological situations via a process known as excitotoxicity. Excessive influx of calcium (Ca²+, and the consequent loss of Ca²+ homeostasis in neurons subject to this form of excessive activation have been suggested to play a central role in the triggering of a series of events ending in neuronal death. Neuronal populations differ in their vulnerability to excitotoxicity and this difference has, controversially, been attributed to the variability in the calcium-load handling capacity of neurons. The latter may possibly reflect the level of expression of the high-capacity calcium-binding proteins such as calbindin-D28K (CaBP). This work aims at studying the potential influence of CaBP expression in cultured hippocampal neurons on agonist- and depolarization-induced Ca²+ responses, and on the vulnerability of these neurons to excitotoxic stimuli. Manipulation of neuronal Ca²+ buffering capacity could also be achieved by loading neurons with BAPTA-like Ca²+ buffers. We tested the hypothesis that enhancing neuronal Ca²+ buffering capacity, either by the expression of CaBP or by loading neurons with BAPTA-like buffers, will render them more resistant to glutamate-induced neuronal death in vitro. We found that neurons expressing CaBP or loaded with an artificial Ca²+ buffer, contrary to our hypothesis, were more vulnerable to excitotoxicity. The mechanism(s) involved in the enhancement of neuronal loss under conditions of increases Ca²+ buffering capacity are likely to include an increase in the net influx of Ca²+, secondary to the impairment ofCa²+-mediated inhibition of Ca²+ influx, and the prolongation of the recovery phase at the end of the excitotoxic stimulus. Such a prolongation may be a result of the increased Ca²+ influx and competition between the recovery mechanisms on one side, and the large number of high affinity Ca²+ binding sites of the buffer on the other. In neurons that express CaBP, an added vulnerability factor may be the consistently higher peak Ca²+ responses to glutamate receptor agonists and to depolarization observed in these neurons when compared to responses in neurons lacking CaBP. The biological effects of enhanced Ca²+ buffering capacity, particularly using fast and mobile buffers, would be subject to the cell-specific nature of the spatial and temporal pattern of the Ca²+ signal. Thus, the influence of Ca²+ buffering on neuronal vulnerability may be difficult to predict on a theoretical basis particularly in view of our results indicating the large impact of many factors in the culture environment on the vital properties of neurons in vitro. [Scientific formulae used in this abstract could not be reproduced.]
Measurement of Dicke Narrowing in Electromagnetically Induced Transparency
Creators: name: Shuker, M.
name: Firstenberg, O.
name: Pugatch, R.
name: Ben-Kish, A.
name: Ron, A.
name: Davidson, N.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Dicke narrowing is a phenomena that dramatically reduces the Doppler width of spectral lines, due to frequent velocity-changing collisions. A similar phenomena occurs for electromagnetically induced transparency (EIT) resonances, and facilitates ultra-narrow spectral features in room-temperature vapor. We directly measure the Dicke-like narrowing by studying EIT line-shapes as a function of the angle between the pump and the probe beams. The measurements are in good agreement with an analytic theory with no fit parameters. The results show that Dicke narrowing can increase substantially the tolerance of hot-vapor EIT to angular deviations. We demonstrate the importance of this effect for applications such as imaging and spatial solitons using a single-shot imaging experiment, and discuss the implications on the feasibility of storing images in atomic vapor.
description: Introduction revised
Measuring the business value of information technology: the case of financial electronic data interchange (EDI) in Canada
Creators: name: Bergeron, Marielle
Publisher: name: University of British Columbia
Year: 2009

description: Why and how much should we invest in this information technology (IT)? The difficulty to formulate well-justified, convincing answers to those questions asked by corporate decision-makers has been identified as a major impediment to one rapid adoption of IT innovations by the business community. This study investigates the fundamental construct underlying these questions by performing a formal assessment of the business value of financial electronic data interchange (EDI) technology for corporate adopters in Canada. Three major Canadian financial institutions, seven cross-industry financial EDI user organizations (originators and receivers), several reference firms and more than fifty individuals actively participated in this study which follows a triangulation data collection approach. Within a cohesive financial EDI value measurement framework based on the theory of capital budgeting, a set of realistic and flexible models for measuring the business value of financial EDI was developed from a rigorous, item-by-item analysis of the data. Following a scenario-based approach, the data and models were used to estimate the magnitude of potential net benefits of financial EDI to corporate adopters. A formal evaluation of the expected and actual costs and benefits of financial EDI to participating user firms was conducted using the models. Several major conclusions were drawn from this in-depth study of financial EDI investments including, among others, the substantiated observation that from a payment process perspective, financial EDI is potentially more beneficial to corporate receivers than originators. Compared to non-financial EDI applications, potential economic gains from reduced payment cycles accrue primarily to the supplier community, rather than the initiators of financial EDI systems. Major contributions of this study include first, the development of a theory-based value measurement framework, and second, the presentation and application of a structured, iterative methodology for the evaluation of financial EDI investments. The proposed financial EDI cost/benefit models also offer a useful, practical set of tools to potential and actual user firms in evaluating the organizational value of future or current financial EDI programs. Finally, the study is also intended to assist Canadian financial institutions in their financial EDI diffusion effort.
title: Designing a Phase IIb trial and its futility interim analyses
Creators: name: Ring, Arne
name: Witt, Anke
name: von der Weth, Renate
name: Scharpenberg, Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: frequentist
subject: Bayesian
subject: 610 Medical sciences; Medicine

description: Background: Phase IIb actively controlled trial with event outcomes shall be designed aiming to obtain sufficient information for planning the subsequent phase III trial. Hence, the sample size of the Phase IIb trial shall be large enough to determine the treatment outcomes with sufficient precision.[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Diagonal Peg Solitaire
Creators: name: Bell, George I.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Combinatorics (math.CO)
subject: Discrete Mathematics (cs.DM)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 00A08; 97A20

description: We study the classical game of peg solitaire when diagonal jumps are allowed. We prove that on many boards, one can begin from a full board with one peg missing, and finish with one peg anywhere on the board. We then consider the problem of finding solutions that minimize the number of moves (where a move is one or more jumps by the same peg), and find the shortest solution to the "central game", which begins and ends at the center. In some cases we can prove analytically that our solutions are the shortest possible, in other cases we apply A* or bidirectional search heuristics.
description: 20 pages, 11 figures
Συμμετοχικός σχεδιασμός στην αρχιτεκτονική τοπίου: μέθοδοι και εργαλεία της κοινωνικής προσέγγισης στο σχεδιασμό.:
Creators: name: Ακτσελή, Ολγα Θεολόγου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Συμμετοχικός
Αρχιτεκτονική
Σχεδιασμός
Participatory
Design
Empowerment

description: Ο συμμετοχικός σχεδιασμό είναι ένα εξελισσόμενος ερευνητικός τομέας και μια αναπτυσσόμενη πρακτική μεταξύ των επαγγελματιών του σχεδιασμού. Αντιπροσωπεύει μια νέα προσέγγιση του σχεδιασμού τοπίου κατά την οποία οι χρήστες ενός τόπου επέμβασης διαδραματίζουν έναν κρίσιμο ρόλο στο σχεδιασμό του, ούτως ώστε το τοπίο να ανταποκρίνονται στις ανάγκες και τις προσδοκίες τους. Για κάποιους, αυτή η προσέγγιση έχει μια πολιτική διάσταση αφού ενδυναμώνει τον πολίτη και προωθεί τον εκδημοκρατισμό. Για άλλους, θεωρείται ένας τρόπος ελαχιστοποίησης της ευθύνης του σχεδιασμού και της καινοτομίας από τους σχεδιαστές. Καθώς η ικανοποίηση των αναγκών και η αίσθηση ευθύνης για το τοπικό περιβάλλον είναι τα βασικά κριτήρια για τη βιώσιμη ανάπτυξη, η παρούσα διατριβή επιχειρεί να διερευνήσει τα κύρια ζητήματα που προκύπτουν πριν από την εφαρμογή του συμμετοχικού σχεδιασμού του τοπίου και ιδιαίτερα (1) τη φύση της συμμετοχής, (2) τις αρχές του σχεδιασμού, (3) τα εργαλεία και τις τεχνικές, (4) τα πλεονεκτήματα της εφαρμογής μιας τέτοιας προσέγγισης και (5) τους κινδύνους σχεδιασμού με μη ειδικούς πολίτες
description: Participatory Design is a maturing field of research and an evolving practice among de¬sign professionals. It represents a new approach towards landscape design in which pos¬sible users of a place play a critical role in designing it in order to meet their needs and aspirations. For some, this approach has a political dimension of user empowerment and democratization. For others, it is seen as a way of minimize design responsibility and in¬novation by designers. As satisfaction of needs and the sense of responsibility for the local surroundings are key criteria for a sustainable development, this paper attempts to inves¬tigate the main issues that occur before implementing participatory landscape design and especially (1) the nature of participation, (2) the politics and principles of PD, (3) tools and techniques, (4) the advantages of implementing such an approach and (5) the hazards of leaving the users to decide.
Additional file 10 of Plastid phylogenomic insights into relationships of all flowering plant families
Creators: name: Li, Hong-Tao
name: Luo, Yang
name: Gan, Lu
name: Ma, Peng-Fei
name: Gao, Lian-Ming
name: Yang, Jun-Bo
name: Cai, Jie
name: Gitzendanner, Matthew A.
name: Fritsch, Peter W.
name: Zhang, Ting
name: Jin, Jian-Jun
name: Zeng, Chun-Xia
name: Wang, Hong
name: Yu, Wen-Bin
name: Zhang, Rong
name: van der Bank, Michelle
name: Olmstead, Richard G.
name: Hollingsworth, Peter M.
name: Chase, Mark W.
name: Soltis, Douglas E.
name: Soltis, Pamela S.
name: Yi, Ting-Shuang
name: Li, De-Zhu
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 10: Figure S9. Topologies of a pruned Maximum Likelihood phylogeny of 431 representative species (“ML431_pruned”) and ASTRAL analysis (“astral431_BS10”) of a 43-species subdataset of angiosperms using 80 plastid genes. The ML bootstrap percentages and ASTRAL local posterior probabilities are shown, respectively.
Επιπτώσεις κλιματολογικών αλλαγών στη γεωργία:
Creators: name: Αθανασιάδου, Στεργιανή Βασιλείου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Κλιματική αλλαγή
Κατακρημνίσματα
Θερμοκρασία
Climate change
Precipitation
Temperature

description: Βασικός σκοπός της παρούσας διατριβής είναι η μελέτη της επίδρασης της κλιματικής αλλαγής στο επίπεδο της γεωργικής παραγωγής στην Ελλάδα και στα υπόλοιπα κράτη-μέλη της Ευρωπαϊκής Ένωσης. Χρησιμοποιήθηκαν πάνελ δεδομένα, ένα σύνολο γεωργικών μεταβλητών στο πλαίσιο της γεωργικής παραγωγής και περιβαλλοντικές μεταβλητές. Διαπιστώθηκε ότι η γεωργική παραγωγή της Ελλάδας έχει αρνητική συσχέτιση με τη θερμοκρασία και την κατακρήμνιση ενώ για την Ευρωπαϊκή Ένωση διαπιστώθηκε το ακριβώς αντίστροφο. Επίσης έγινε μία πρόβλεψη σε επίπεδο δεκαετίας για τις τρεις βασικές μεταβλητές της εργασίας (γεωργική παραγωγή, κατακρημνίσματα, θερμοκρασία) με σκοπό να διαπιστωθεί ο τρόπος μεταβολής τους.
description: The main purpose of this thesis is to estimate the impact of climate change on the level of agricultural production in Greece and other member-states of the European Union. Panel data were used, including a set of agricultural variables in agricultural production and environmental variables. The results suggest that agricultural production in Greece has a negative correlation with temperature and rainfall while for the European Union results indicate the exact opposite. There was also a provision at the decade for the three primary variables of this paper (agricultural production, precipitation, temperature) in order to forecast their change.
title: Analysis and sample size calculation within the Response Specific Exponential Survival (RSES) model
Creators: name: Kilian, Samuel
name: Krisam, Johannes
name: Kieser, Meinhard
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: survival analysis
subject: surrogate endpoint
subject: expedited approval
subject: sample size calculation
subject: statistical testing
subject: 610 Medical sciences; Medicine

description: Background: Endpoints of clinical trials should be appropriate for the medical question, objectively measurable, and relevant for patients. Therefore, overall survival is usually the primary endpoint in oncology. However, when comparing a new therapy with the present gold standard, differences in overall[for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
Can the third dredge-up extinguish hot-bottom burning in massive AGB stars?
Creators: name: Marigo, Paola
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Marigo (2002) has highlighted the crucial importance of molecular opacities in modelling the evolution of AGB stars at varying surface C/O ratio. In particular, it has been shown the large inadequacy of solar-scaled opacities when applied to models of carbon stars, and hence the need for correctly coupling the molecular opacities to the current surface chemical composition of AGB stars. The aim of the present follow-up study is to investigate the effects of variable molecular opacities on the evolutionary properties of luminous AGB stars with massive envelopes, i.e. with initial masses from ~3.5 Msun up to 5-8 Msun, which are predicted to experience both the third dredge-up and hot-bottom burning. It is found that if the dredge-up of carbon is efficient enough to lead to an early transition from C/O<1 to C/O>1, then hot-bottom burning may be weakened, extinguished, or even prevented. The physical conditions for this occurrence are analysed and a few theoretical and observational implications are discussed. Importantly, it is found that the inclusion of variable molecular opacities could significantly change the current predictions for the chemical yields contributed by intermediate-mass AGB stars, with M~3.5 - 4.0 Msun that make as much as ~ 30-50 % of all stars expected to undergo hot-bottom burning.
description: 10 pages, 5 figures, accepted for publication in A&A
Additional file 1 of Analysis of sex-based differences in clinical and molecular responses to ischemia reperfusion after lung transplantation
Creators: name: Chacon-Alberty, Lourdes
name: Ye, Shengbin
name: Daoud, Daoud
name: Frankel, William C.
name: Virk, Hassan
name: Mase, Jonathan
name: Hochman-Mendez, Camila
name: Li, Meng
name: Sampaio, Luiz C.
name: Taylor, Doris A.
name: Loor, Gabriel
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: Additional file 1: Demographic and clinical characteristics of 40 lung transplant recipients with prospectively collected biomarkers.
Ευθύνη στρατιωτικών διοικητών και πολιτικών προϊσταμένων: μεταξύ αυτουργίας και συμμετοχής:
Creators: name: Ανδρεάδης-Παπαδημητρίου, Παύλος Αλέξανδρου-Λεωνίδα
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: ευθύνη ανωτέρων
αυτουργία
έμμεση αυτουργία
συμμετοχή
γνήσιο έγκλημα παράλειψης
ιδιόμορφο είδος ποινικής ευθύνης
superior responsibility
mode of liability
direct or indirect perpetration
accessorial liability
separate crime of omission
sui generis mode of attribution

description: Τα εγκλήματα που τυποποιούνται στο Καταστατικό του Διεθνούς Ποινικού Δικαστηρίου συνήθως τελούνται από πρόσωπα που είναι ενταγμένα σε ιεραρχικά δομημένους συλλογικούς σχηματισμούς. Τα πρόσωπα αυτά κατά κανόνα δρουν είτε σε εκτέλεση διαταγών των ιεραρχικά ανωτέρων τους, είτε σε εκτέλεση ενός σχεδίου που οργανώθηκε από κοινού με αυτούς, είτε αυτόνομα, όταν οι ανώτεροί τους δεν ασκούν την κατάλληλη εποπτεία. Οι τελευταίοι με τη σειρά τους όμως κατέχουν μία εγγυητική θέση απέναντι στα έννομα αγαθά που ενδέχεται να κινδυνεύσουν από τη δράση του σχηματισμού που διοικούν, και για το λόγο αυτό έχουν μια ιδιαίτερη υποχρέωση να αποτρέπουν τις προσβολές τους κατά παράβαση του διεθνούς δικαίου. Η θέση αυτή αποτελεί το θεμέλιο του άρθρου 28 ΚΔΠΔ, με το οποίο αναγνωρίζεται η ποινική ευθύνη των ανωτέρων για την παράλειψη της αποτροπής ή της καταστολής τέτοιων προσβολών. Η μελέτη διερευνά τις ειδικότερες προϋποθέσεις του, αλλά και τις δογματικές του προεκτάσεις, καθώς δεν είναι εξ αρχής σαφές αν τελικά πρόκειται για ένα αυτοτελές έγκλημα, για ευθύνη αυτουργική ή συμμετοχική, ή για ένα εντελώς ιδιόμορφο είδος ποινικής ευθύνης.
description: Crimes under the jurisdiction of the International Criminal Court are typically committed by members of hierarchically organised structures, often in adherence to superior orders or as part of a joint criminal effort of superiors and subordinates alike. In some occasions, however, subordinates may commit these crimes not because they were so ordered, but as a result of improper supervision by their superiors, who in turn are under a duty to ensure the proper conduct of their subordinates and prevent violations of international criminal law. This principle is codified in article 28 of the Rome Statute, which provides for the individual criminal responsibility of superiors who fail to prevent, repress or report such crimes to the competent authorities. Its interpretation, however, is far from a simple task, not only due to its somewhat obscure wording, but also because of its ambiguity regarding the precise offence and mode of attribution. The dissertation endeavours to clarify the doctrine of superior responsibility and reflects on whether article 28 of the Rome Statute constitutes a separate offence or conforms to traditional forms of attribution, or whether, as a sui generis scheme, it actually transcends them.
title: Dose-Response-Metaanalysen für Fragestellungen in der Versorgungsforschung
Creators: name: Mathes, Tim
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: In der Versorgungsforschung existieren häufig Fragestellungen, bei denen Expositionen mit mehr als einer Ausprägung vorliegen (z.B. Menge einer Leistung). Standard Metaanalyse-Verfahren (SMA) sind nur für den Vergleich von zwei Expositionen(-sausprägungen) geeignet. [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)
The cosmological billiard attractor
Creators: name: Heinzle, J. Mark
name: Uggla, Claes
name: Rohr, Niklas
Publisher: name: arXiv
Year: 2007
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This article is devoted to a study of the asymptotic dynamics of generic solutions of the Einstein vacuum equations toward a generic spacelike singularity. Starting from fundamental assumptions about the nature of generic spacelike singularities we derive in a step-by-step manner the cosmological billiard conjecture: we show that the generic asymptotic dynamics of solutions is represented by (randomized) sequences of heteroclinic orbits on the `billiard attractor'. Our analysis rests on two pillars: (i) a dynamical systems formulation based on the conformal Hubble-normalized orthonormal frame approach expressed in an Iwasawa frame; (ii) stochastic methods and the interplay between genericity and stochasticity. Our work generalizes and improves the level of rigor of previous work by Belinskii, Khalatnikov, and Lifshitz; furthermore, we establish that our approach and the Hamiltonian approach to `cosmological billiards', as elaborated by Damour, Hennaux, and Nicolai, can be viewed as yielding `dual' representations of the asymptotic dynamics.
description: 88 pages, 18 figures
Σχεδιασμός και υλοποίηση έρευνας ερωτηματολογίου ικανοποίησης επιβατών στις δημόσιες συγκοινωνίες
Creators: name: Αντωνίου, Πηνελόπη-Κοκονιά Χριστόφορου
Publisher: name: Aristotle University of Thessaloniki
Year: 2013
Subjects: Δημόσιες Συγκοινωνίες
Ποιότητα
Έρευνες ικανοποίησης επιβατών
Public transport
Quality
Passenger satisfaction surveys

description: Αντικείμενο και σκοπός της διπλωματικής εργασίας ήταν η ανάδειξη των ερευνών ικανοποίησης επιβατών ως σημαντικό εργαλείο για την εκτίμηση της αντιληπτής ποιότητας εξυπηρέτησης των δημοσίων συγκοινωνιών και η υλοποίηση αντίστοιχης έρευνας ερωτηματολογίου στις αστικές συγκοινωνίες της Θεσσαλονίκης. Αρχικά εξετάστηκε ο ορισμός της ποιότητας στις Δημόσιες Συγκοινωνίες και οι διάφορες εκφάνσεις της και παρουσιάστηκε η μεθοδολογία προσδιορισμού ποιότητας και τα κριτήρια ποιότητας σύμφωνα με το Ευρωπαϊκό πρότυπο ΕΝ13816:2002. Στη συνέχεια έγινε αναλυτική αναφορά στην έννοια της ικανοποίησης πελατών, στις έρευνες ικανοποίησης πελατών γενικά και ειδικότερα στον τομέα των υπηρεσιών, όπως είναι και οι δημόσιες συγκοινωνίες. Τέλος, παρουσιάστηκε η μεθοδολογία που ακολουθήθηκε για την εκπόνηση έρευνας ικανοποίησης επιβατών στην Θεσσαλονίκη και τα αποτελέσματά της, τα οποία οδήγησαν σε κάποια συμπεράσματα και προτάσεις.
description: The aim and objective of this thesis was to highlight passenger satisfaction surveys as an important tool for assessing the perceived service quality of public transport and the implementation of corresponding questionnaire research in urban transport of Thessaloniki. Firstly, the definition of quality in public transport and its various facets were examined and then the methodology of determination of quality and the quality criteria according to EN13816:2002 were presented. Then, a detailed reference to the concept of customer satisfaction was made, in terms of customer satisfaction surveys in general and in particular in the services’ sector, such as public transport. Finally, the methodology used to implement passenger satisfaction survey in Thessaloniki was presented, the results of this survey were presented and led to some conclusion and suggestions.
"Putkisalon kartano" farm, Rantasalmi, Finland - Gospodarstwo "Putkisalon kartano", Rantasalmi, Finlandia
Creators: name: Herder, Michael Den
Publisher: name: Zenodo
Year: 2018
Subjects: sheep
wooded pasture
lamb
wool
eco-tourism
owce
zadrzewione pastwisko
jagnięcina
wełna
agroturystyka

description: Gospodarstwo "Putkisalo kartano" znajduje się 300 km na północ od Helsinek. Obejmuje 20 ha pastwiska leśnego, z tego część mającą ponad 200 lat. Gospodarstwo zajmuje się hodowlą owiec i produkcją baraniny, jagnięciny oraz uprawą zbóż. Posiada również las produkcyjny oraz zarządza tradycyjnym krajobrazem wiejskim. Zapoznajcie się bliżej z tym wszechstronnym gospodarstwem!
title: Incorporation of Multiple Studies in Adjusted Indirect Comparisons
Creators: name: Weber, Dorothea
name: Jensen, Katrin
name: Kieser, Meinhard
Publisher: name: German Medical Science GMS Publishing House
Year: 2021
Subjects: subject: 610 Medical sciences; Medicine

description: Objective: In evidence synthesis, indirect comparisons are widely used to compare treatments where direct evidence is missing. However, methods for indirect comparisons showed bad performance in terms of power. The matching adjusted indirect comparison (MAIC) [ref:1] procedure is designed [for full text, please go to the a.m. URL]
description: 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)