cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Vaccine-induced skewing of t cell responses protects against chikungunya virus disease
Creators: name: Streblow, Daniel N.
name: Broeckel, Rebecca M.
name: Smith, Patricia
name: Dmitriev, Igor
name: DeFilippis, Victor
name: Messaoudi, Ilhem
name: Morrison, Thomas E.
name: Ando, Takeshi
name: Kreklywich, Craig N.
name: Haese, Nicole
name: Denton, Michael
name: Power, John
name: Curiel, David T.
name: Heise, Mark
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Chikungunya virus (CHIKV) infections can cause severe and debilitating joint and muscular pain that can be long lasting. Current CHIKV vaccines under development rely on the generation of neutralizing antibodies for protection; however, the role of T cells in controlling CHIKV infection and disease is still unclear. Using an overlapping peptide library, we identified the CHIKV-specific T cell receptor epitopes recognized in C57BL/6 infected mice at 7 and 14 days post-infection. A fusion protein containing peptides 451, 416, a small region of nsP4, peptide 47, and an HA tag (CHKVf5) was expressed using adenovirus and cytomegalovirus-vectored vaccines. Mice vaccinated with CHKVf5 elicited robust T cell responses to higher levels than normally observed following CHIKV infection, but the vaccine vectors did not elicit neutralizing antibodies. CHKVf5-vaccinated mice had significantly reduced infectious viral load when challenged by intramuscular CHIKV injection. Depletion of both CD4+ and CD8+ T cells in vaccinated mice rendered them fully susceptible to intramuscular CHIKV challenge. Depletion of CD8+ T cells alone reduced vaccine efficacy, albeit to a lesser extent, but depletion of only CD4+ T cells did not reverse the protective phenotype. These data demonstrated a protective role for CD8+ T cells in CHIKV infection. However, CHKVf5-vaccinated mice that were challenged by footpad inoculation demonstrated equal viral loads and increased footpad swelling at 3 dpi, which we attributed to the presence of CD4 T cell receptor epitopes present in the vaccine. Indeed, vaccination of mice with vectors expressing only CHIKV-specific CD8+ T cell epitopes followed by CHIKV challenge in the footpad prevented footpad swelling and reduced proinflammatory cytokine and chemokines associated with disease, indicating that CHIKV-specific CD8+ T cells prevent CHIKV disease. These results also indicate that a T cell-biased prophylactic vaccination approach is effective against CHIKV challenge and reduces CHIKV-induced disease in mice.
Simulation of Anderson localization in two-dimensional ultracold gases for point-like disorder
Creators: name: Morong, William
name: DeMarco, Brian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Anderson localization has been observed for a variety of media, including ultracold atomic gases with speckle disorder in one and three dimensions. However, observation of Anderson localization in a two-dimensional geometry for ultracold gases has been elusive. We show that a cause of this difficulty is the relatively high percolation threshold of a speckle potential in two dimensions, resulting in strong classical localization. We propose a realistic point-like disorder potential that circumvents this percolation limit with localization lengths that are experimentally observable. The percolation threshold is evaluated for experimentally realistic parameters, and a regime of negligible classical trapping is identified. Localization lengths are determined via scaling theory, using both exact scattering cross sections and the Born approximation, and by direct simulation of the time-dependent Schrödinger equation. We show that the Born approximation can underestimate the localization length by four orders of magnitude at low energies, while exact cross sections and scaling theory provide an upper bound. Achievable experimental parameters for observing localization in this system are proposed.
The Collaborative Cross: A Systems Genetics Resource for Studying Host-Pathogen Interactions
Creators: name: Noll, Kelsey E.
name: Ferris, Martin T.
name: Heise, Mark T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Host genetic variation plays an important role in shaping infectious disease susceptibility. Noll et al. review the application of a genetically diverse mouse reference population, the Collaborative Cross, to study variation in disease response across multiple pathogens, highlighting advances in model development and genetic mapping. © 2019 Elsevier Inc.Host genetic variation has a major impact on infectious disease susceptibility. The study of pathogen resistance genes, largely aided by mouse models, has significantly advanced our understanding of infectious disease pathogenesis. The Collaborative Cross (CC), a newly developed multi-parental mouse genetic reference population, serves as a tractable model system to study how pathogens interact with genetically diverse populations. In this review, we summarize progress utilizing the CC as a platform to develop improved models of pathogen-induced disease and to map polymorphic host response loci associated with variation in susceptibility to pathogens.
Electronic Supplementary Material from Ocular lens morphology is influenced by ecology and metamorphosis in frogs and toads
Creators: name: Mitra, Amartya T.
name: Womack, Molly C.
name: Gower, David J.
name: Streicher, Jeffrey W.
name: Clark, Brett
name: Bell, Rayna C.
name: Schott, Ryan K.
name: Fujita, Matthew K.
name: Thomas, Kate N.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Supplementary materials for Mitra et al. (2022) Ocular lens morphology is influenced by ecology and metamorphosis in frogs and toads
The universality of the virial halo mass function and models for non-universality of other halo definitions
Creators: name: Despali, Giulia
name: Giocoli, Carlo
name: Angulo, Raul E.
name: Tormen, Giuseppe
name: Sheth, Ravi K.
name: Baso, Giacomo
name: Moscardini, Lauro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The abundance of galaxy clusters can constrain both the geometry and growth of structure in our Universe. However, this probe could be significantly complicated by recent claims of nonuniversality -- non-trivial dependences with respect to the cosmological model and redshift. In this work we analyse the dependance of the mass function on the way haloes are identified and establish if this can cause departures from universality. In order to explore this dependance, we use a set of different N-body cosmological simulations (Le SBARBINE simulations), with the latest cosmological parameters from the Planck collaboration; this first suite of simulations is followed by a lower resolution set, carried out with different cosmological parameters. We identify dark matter haloes using a Spherical Overdensity algorithm with varying overdensity thresholds (virial, 2000rho_c, 1000rho_c, 500rho_c, 200rho_c and 200rho_b) at all redshifts. We notice that, when expressed in term of the rescaled variable nu, the mass functionfor virial haloes is a nearly universal as a function of redshift and cosmology, while this is clearly not the case for the other overdensities we considered. We provide fitting functions for the halo mass function parameters as a function of overdensity, that allow to predict, to within a few percent accuracy, the halo mass function for a wide range of halo definitions, redshifts and cosmological models. We then show how the departures from universality associated with other halo definitions can be derived by combining the universality of the virial definition with the expected shape of the density profile of halos.
description: 22 pages, 21 figures, accepted for publication in MNRAS - some changes with respect to the previous version and a new appendix
CudaChain: A Practical GPU-accelerated 2D Convex Hull Algorithm
Creators: name: Mei, Gang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Geometry (cs.CG)
subject: FOS: Computer and information sciences

description: This paper presents a practical GPU-accelerated convex hull algorithm and a novel Sorting-based Preprocessing Approach (SPA) for planar point sets. The proposed algorithm consists of two stages: (1) two rounds of preprocessing performed on the GPU and (2) the finalization of calculating the expected convex hull on the CPU. We first discard the interior points that locate inside a quadrilateral formed by four extreme points, and then distribute the remaining points into several (typically four) sub regions. For each subset of points, we first sort them in parallel, then perform the second round of discarding using SPA, and finally form a simple chain for the current remaining points. A simple polygon can be easily generated by directly connecting all the chains in sub regions. We at last obtain the expected convex hull of the input points by calculating the convex hull of the simple polygon. We use the library Thrust to realize the parallel sorting, reduction, and partitioning for better efficiency and simplicity. Experimental results show that our algorithm achieves 5x ~ 6x speedups over the Qhull implementation for 20M points. Thus, this algorithm is competitive in practical applications for its simplicity and satisfied efficiency.
Some advances on Sidorenko's conjecture
Creators: name: Conlon, David
name: Kim, Jeong Han
name: Lee, Choongbum
name: Lee, Joonkyung
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: A bipartite graph $H$ is said to have Sidorenko's property if the probability that the uniform random mapping from $V(H)$ to the vertex set of any graph $G$ is a homomorphism is at least the product over all edges in $H$ of the probability that the edge is mapped to an edge of $G$. In this paper, we provide three distinct families of bipartite graphs that have Sidorenko's property. First, using branching random walks, we develop an embedding algorithm which allows us to prove that bipartite graphs admitting a certain type of tree decomposition have Sidorenko's property. Second, we use the concept of locally dense graphs to prove that subdivisions of certain graphs, including cliques, have Sidorenko's property. Third, we prove that if $H$ has Sidorenko's property, then the Cartesian product of $H$ with an even cycle also has Sidorenko's property.
description: 19 pages
Studies on Dibenzylamines as Inhibitors of Venezuelan Equine Encephalitis Virus
Creators: name: Rasmussen, Lynn
name: Bonin, Kiley
name: Streblow, Cassilyn
name: Tower, Nichole A.
name: Heise, Mark T.
name: Augelli-Szafran, Corinne E.
name: Sarkar, Sanjay
name: Taft-Benz, Sharon
name: Morrison, Thomas E.
name: Haese, Nicole
name: DeFilippis, Victor
name: Nguyen, Theresa H.
name: Pathak, Ashish K.
name: Bostwick, Robert
name: Streblow, Daniel N.
name: Madadi, Nikhil
name: Suto, Mark J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Alphaviruses are arthropod-transmitted members of the Togaviridae family that can cause severe disease in humans, including debilitating arthralgia and severe neurological complications. Currently, there are no approved vaccines or antiviral therapies directed against the alphaviruses, and care is limited to treating disease symptoms. A phenotypic cell-based high-throughput screen was performed to identify small molecules that inhibit the replication of Venezuelan Equine Encephalitis Virus (VEEV). The compound, 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-fluoro-4-methoxybenzyl)ethan-1-amine (1), was identified as a highly active, potent inhibitor of VEEV with an effective concentration for 90% inhibition of virus (EC90) of 0.89 μM and 7.49 log reduction in virus titers at 10 μM concentration. These data suggest that further investigation of compound 1 as an antiviral therapeutic against VEEV, and perhaps other alphaviruses, is warranted. Experiments suggested that the antiviral activity of compound 1 is directed at an early step in the VEEV replication cycle by blocking viral RNA and protein synthesis.
การศึกษาปัญหาสุนัขจรจัดในบริบทชุมชนเมืองสู่แนวทางการแก้ปัญหาด้วยสถาปัตยกรรมขนาดเล็ก
Creators: name: ยศพร จันทองจีน
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: ปัญหาสุนัขจรจัด
สถาปัตยกรรมขนาดเล็ก
สวัสดิภาพสุนัข

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 1-14
Quantum Phase Analysis of Field-Free Molecular Alignment
Creators: name: Yun, Sang Jae
name: Kim, Chul Min
name: Lee, Jongmin
name: Nam, Chang Hee
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We present quantum mechanical explanations for unresolved phenomena observed in field-free molecular alignment by a femtosecond laser pulse. Quantum phase analysis of molecular rotational states reveals the physical origin of the following phenomena: strong alignment peaks appear periodically, and the temporal shape of each alignment peak changes in an orderly fashion depending on molecular species; the strongest alignment is not achieved at the first peak; the transition between aligned and anti-aligned states is very fast compared to the time scale of rotational dynamics. These features are understood in a unified way analogous to that describing a carrier-envelope-phase-stabilized mode-locked laser.
Apios delavayi var. pteridietorum Handel-Mazzetti 1933
Creators: name: Zhang, Fan
name: Feng, Si
name: Zhou, Jianjun
name: Zhang, Rong
name: Liu, Linhan
name: Yang, Chengzi
name: Yu, Xunlin
name: Pan, Bo
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Apios
Apios delavayi
Apios delavayi var. pteridietorum handel-Mazzetti (1933: 580)

description: Apios delavayi var. pteridietorum Handel-Mazzetti (1933: 580).
 Type:— CHINA. Yunnan: Salween, H. Handel-Mazzetti 8990 (holotype WU! Isotype E!).
 Flowers yellowish violet, light purple, or dark purple. This variety represents A. delavayi populations west of the Mekong-Salween Divide.
 Distribution and habitat: —This variety is distributed in China (Xizang and Yunnan) and India (Assam). It grows in pine forests, mixed forests or thickets at elevations between 1700–3500 m above sea level.
 Phenology: —Flowering from June to September; fruiting from July to October.
 Specimens examined:— CHINA. Xizang: Baiba, 17 June 1952, Bu-Qiu Zhong 6643 (PE). Bomi, between Bomi and Tongmai, 2600–2800 m, Su-Gong Wu et al. 105962 (KUN). Chayu, Xialun, 1860 m, 31 July 1980, Zhi-Cheng Ni et al. 942 (PE). Chayu, Tongmai to Lulang, 2210 m, 27 July 1965, Yong-Tian Zhang & Kai-Yong Lang 939 (PE). Gorge of the Tsangpo, 8000–10000 ft, 19 July1924, F.K. Ward 5961 (E). Linzhi, Dongjiu to Chayuan, 2900 m, 17 June 1972, Xizang Medicinal Plants Team 3466 (PE). Pome, near Showa, Satang, 7500 ft, 19 September 1947, Ludlow et al. 13192 (E). Salween-Kiuchiang Divide, July 1919, G. Forrest 19321 (E). Salween valley, 10000 ft, 22 October 1917, F.K. Ward 5420 (E). Yunnan: Deqin, 3000 m, July 1935, Qi-Wu Wang 64738 (PE). Dulongjiang, Longdang to Longjigeng, 1900–2100 m, 3 September 1982, Qingzang Team 9873 (KUN). Gongshan, Yu’en, 3300 m, 25 August 1940, Feng 6898 (PE). Kiukiang Valley, Taron, Chiengen, 1700 m, 26 July 1938, T.T. Yü 19419 (E, PE). INDIA. Assam: Di Chu Gorge, 7000 ft, 6 August 1950, F.K. Ward 20115 (E).
description: Published as part of Zhang, Fan, Feng, Si, Zhou, Jianjun, Zhang, Rong, Liu, Linhan, Yang, Chengzi, Yu, Xunlin & Pan, Bo, 2018, Apios chendezhaoana (Fabaceae), an overlooked species and a new combination from China: evidence from morphological and molecular analyses, pp. 1-16 in Phytotaxa 371 (1) on page 10, DOI: 10.11646/phytotaxa.371.1.1, http://zenodo.org/record/13728810
Ross River virus envelope glycans contribute to disease through activation of the host complement system
Creators: name: Heise, Mark T.
name: Gunn, Bronwyn
name: Jones, Jennifer E.
name: Sarkar, Sanjay
name: Whitmore, Alan C.
name: Morrison, Thomas E.
name: Blevins, Lance K.
name: Shabman, Reed S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Mannose binding lectin (MBL) generally plays a protective role during viral infection, yet MBL-mediated complement activation promotes Ross River virus (RRV)-induced inflammatory tissue destruction, contributing to arthritis and myositis. As MBL binds to carbohydrates, we hypothesized that N-linked glycans on the RRV envelope glycoproteins act as ligands for MBL. Using a panel of RRV mutants lacking the envelope N-linked glycans, we found that MBL deposition onto infected cells was dependent on the E2 glycans. Moreover, the glycan-deficient viruses exhibited reduced disease and tissue damage in a mouse model of RRV-induced myositis compared to wild-type RRV, despite similar viral load and inflammatory infiltrates within the skeletal muscle. Instead, the reduced disease induced by glycan-deficient viruses was linked to decreased MBL deposition and complement activation within inflamed tissues. These results demonstrate that the viral N-linked glycans promote MBL deposition and complement activation onto RRV-infected cells, contributing to the development of RRV-induced myositis.
การพัฒนาผลิตภัณฑ์ชุมชนประเภทของที่ระลึกด้วยศิลปะทวารวดี
Creators: name: ณิชกานต์ ไชยจักร์
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: วิสาหกิจชุมชน
ผลิตภัณฑ์ชุมชน
ของที่ระลึก
ศิลปะทวารวดี

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 15-28
ภูมิปัญญาท้องถิ่นตาลโตนดของชุมชนตำบลห้วยกรด อำเภอสรรคบุรี จังหวัดชัยนาท
Creators: name: จุฑารัตน์ นกแก้ว
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: ตาลโตนดห้วยกรด
ภูมิปัญญาท้องถิ่นตาลโตนด
องค์ความรู้ภูมิปัญญาท้องถิ่นตาลโตนดห้วยกรด
อาชีพทำตาล

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 29-41
title: Mental health stigma and professional help-seeking attitudes a comparison between Cuba and Germany
Creators: name: Nohr, Laura
name: Ruiz, Alexis Lorenzo
name: Sandoval Ferrer, Juan E.
name: Buhlmann, Ulrike
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2022
Subjects: subject: 150 Psychology

description: Globally the burden due to mental disorders is continuously increasing. Still, professional help-seeking behavior is not fully understood. To conceive cultural determinants of help-seeking is crucial to reduce personal and social costs of (untreated) mental disorders. The current study investigates mental health stigma and help-seeking attitudes in a Cuban (n = 195) and a German (n = 165) sample. In a questionnaire survey we asked for attitudes towards mental illness and professional help-seeking in the general Cuban and German populations. The cultural context was associated with mental health stigma and professional help-seeking attitudes. Interestingly, Cuban participants reported stronger mental health stigma and more willingness to seek help. In multiple hierarchical regression analyses, community attitudes towards the mentally ill significantly predicted help-seeking attitudes, especially in the Cuban sample. Only in the German sample, more negative individual beliefs about mental illness predicted more self-stigma on help-seeking. Beyond that, cultural context moderated the association between mental health stigma and help-seeking attitudes with a stronger association between the measures in the German sample. However, gender did not predict help-seeking attitudes and self-stigma on help-seeking and no interactions between community attitudes, cultural context, and gender were found in the prediction of help-seeking attitudes. Similarities and differences between the samples are discussed in the light of the cultural contexts and peculiarities of the current samples. Concluding, implications of the current findings are reviewed.
description: Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Towards relativistic quantum geometry
Creators: name: Ridao, Luis Santiago
name: Bellini, Mauricio
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We obtain a gauge-invariant relativistic quantum geometry by using a Weylian-like manifold with a geometric scalar field which provides a gauge-invariant relativistic quantum theory in which the algebra of the Weylian-like field depends on observers. An example for a Reissner-Nordström black-hole is studied.
description: 9 pages, no figures, improved version
คำฉันท์สรเสริญพระมหามณีรัตนปฏิมากร : การศึกษาในฐานะวรรณกรรมเฉลิมพระเกียรติ
Creators: name: ณัฐพล ใจเอี่ยม
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: คำฉันท์สรเสริญพระมหามณีรัตนปฏิมากร
วรรณกรรมเฉลิมพระเกียรติ
แนวคิดการเฉลิมพระเกียรติ

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 42-58
Liquid-liquid dewetting: Morphologies and rates
Creators: name: Bommer, Stefan
name: Seemann, Ralf
name: Jachalski, Sebastian
name: Peschka, Dirk
name: Wagner, Barbara
Publisher: name: Weierstrass Institute
Year: 2016
Subjects: subject: Free boundary problems
subject: interface dynamics
subject: experimental methods
subject: numerical simulations
subject: 68.05.Cf
subject: 02.60.Cb

description: The dependence of the dissipation on the local details of the flow field of a liquid polymer film dewetting from a liquid polymer substrate is shown, solving the free boundary problem for a two-layer liquid system. As a key result we show that the dewetting rates of such a liquid bi-layer system can not be described by a single power law but shows transient behaviour of the rates, changing from increasing to decreasing behaviour. The theoretical predictions on the evolution of morphology and rates of the free surfaces and free interfaces are compared to measurements of the evolution of the polystyrene(PS)-air, the polymethyl methacrylate (PMMA)-air and the PS-PMMA interfaces using in situ atomic force microscopy (AFM), and they show excellent agreement.
การศึกษาผู้นำในวรรณกรรมสามก๊กด้วยทฤษฎีจิตวิทยาบุคลิกภาพ
Creators: name: บุษดี อรสิริวรรณ
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: สามก๊ก
ผู้นำ
บุคลิกภาพ

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 59-74
นวัตกรรมการพัฒนาตัวแบบการนำนโยบายการกระจายอำนาจสู่การปฏิบัติ เพื่อส่งเสริมความเป็นอิสระในการบริหารสถานศึกษาขั้นพื้นฐาน
Creators: name: วิสุทธิ์ วิจิตรพัชราภรณ์
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: นวัตกรรมการพัฒนาตัวแบบ
การนำนโยบายสู่การปฏิบัติ
ความเป็นอิสระในการบริหารสถานศึกษา

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 75-87
The Future of the University: Commonalities Between Research 1 Institutions With Significant Graduate-Level Online Enrollments
Creators: name: Rodenfels, Jack
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019
Subjects: Qualitative research
Distance education
Web-based instruction
Postsecondary education

description:  The purpose of this research study is to identify the shared characteristics for developing and administering online learning initiatives among leading nonprofit higher education institutions. By conducting qualitative, in-depth interviews with university leadership at 12 of the 15 institutions enrolling the greatest amount of online graduate students, the researcher identified the commonalities present in regard to developing and administering online graduate courses for their respective institution.  

The findings revealed that graduate-level online learning helps expand access to the institution for an alternative type of learner. University leadership prioritized online learning by promoting its virtues and looked for avenues to strategically grow online learning opportunities on their respective campuses. These schools largely developed and administered online learning through a centralized unit that works to build relationships with faculty members across their campuses. The findings conclude as leaders considered the future of online learning at higher education institutions and how it will evolve over time. 
This research is meant for leadership at higher education institutions who are interested in mobilizing and scaling online learning opportunities at their respective campus by adapting and implementing the commonalities gleaned from leaders in the field in a way that is authentic and fits within the mission and vision of each individual institution.
Electronic structures of ferromagnetic superconductors $\mathrm{UGe}_2$ and $\mathrm{UCoGe}$ studied by angle-resolved photoelectron spectroscopy
Creators: name: Fujimori, Shin-ichi
name: Ohkochi, Takuo
name: Kawasaki, Ikuto
name: Yasui, Akira
name: Takeda, Yukiharu
name: Okane, Tetsuo
name: Saitoh, Yuji
name: Fujimori, Atsushi
name: Yamagami, Hiroshi
name: Haga, Yoshinori
name: Yamamoto, Etsuji
name: Onuki, Yoshichika
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The electronic structures of the ferromagnetic superconductors $\mathrm{UGe}_2$ and $\mathrm{UCoGe}$ in the paramagnetic phase were studied by angle-resolved photoelectron spectroscopy using soft X-rays ($hν=400-500$). The quasi-particle bands with large contributions from $\mathrm{U}~5f$ states were observed in the vicinity of $E_\mathrm{F}$, suggesting that the $\mathrm{U}~5f$ electrons of these compounds have an itinerant character. Their overall band structures were explained by the band-structure calculations treating all the $\mathrm{U}~5f$ electrons as being itinerant. Meanwhile, the states in the vicinity of $E_\mathrm{F}$ show considerable deviations from the results of band-structure calculations, suggesting that the shapes of Fermi surface of these compounds are qualitatively different from the calculations, possibly caused by electron correlation effect in the complicated band structures of the low-symmetry crystals. Strong hybridization between $\mathrm{U}~5f$ and $\mathrm{Co}~3d$ states in $\mathrm{UCoGe}$ were found by the $\mathrm{Co}~2p-3d$ resonant photoemission experiment, suggesting that $\mathrm{Co}~3d$ states have finite contributions to the magnetic, transport, and superconducting properties.
description: 9 pages, 4 figures
Auxiliary master equation approach within matrix product states: Spectral properties of the nonequilibrium Anderson impurity model
Creators: name: Dorda, Antonius
name: Ganahl, Martin
name: Evertz, Hans Gerd
name: von der Linden, Wolfgang
name: Arrigoni, Enrico
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Within the recently introduced auxiliary master equation approach it is possible to address steady state properties of strongly correlated impurity models, small molecules or clusters efficiently and with high accuracy. It is particularly suited for dynamical mean field theory in the nonequilibrium as well as in the equilibrium case. The method is based on the solution of an auxiliary open quantum system, which can be made quickly equivalent to the original impurity problem. In its first implementation a Krylov space method was employed. Here, we aim at extending the capabilities of the approach by adopting matrix product states for the solution of the corresponding auxiliary quantum master equation. This allows for a drastic increase in accuracy and permits us to access the Kondo regime for large values of the interaction. In particular, we investigate the nonequilibrium steady state of a single impurity Anderson model and focus on the spectral properties for temperatures T below the Kondo temperature T_K and for small bias voltages phi. For the two cases considered, with T=T_K/4 and T=T_K/10 we find a clear splitting of the Kondo resonance into a two-peak structure for phi close above T_K. In the equilibrium case (phi=0) and for T=T_K/4, the obtained spectral function essentially coincides with the one from numerical renormalization group.
description: 11 pages, 10 figures
Klebsiella pneumoniae LCT-KP182 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2013
Subjects: Genome sequencing and assembly
Monoisolate

description: In 2011, Shenzhou 8 took the strain of K. pneumoniae to the outer space about 17 days. After the successful landing, the strain become hemolysis to the sheep blood agar culture plates.
Klebsiella pneumoniae LCT-KP289 Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2013
Subjects: Genome sequencing and assembly
Monoisolate

description: In 2011, Shenzhou 8 took the strain of K. pneumoniae to the outer space about 17 days. After the successful landing, cotrimoxazole resistance found in the strain.
Salix arbutifolia strain:Kuandian Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2013
Subjects: genome sequencing
Monoisolate

description: The genomic analysis of S. arbutifolia may supply abundant genetic resources for full research and utilization of willow, and a detailed genomic comparison of S. arbutifolia and P. trichocarpa may provide insights into the evolution of the Salicaceae genome organization and the identification of the genetic background of their economically and biologically important traits. Collected from a natural forest of Dandong in the Liaoning Province of China
ความต้องการจำเป็นของการบริหารวิชาการโรงเรียนปฐมวัย ตามแนวคิดทักษะสมองเพื่อชีวิตที่สำเร็จ
Creators: name: ระวีวรรณ ทิพยานนท์
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: ทักษะสมองเพื่อชีวิตที่สำเร็จ
โรงเรียนปฐมวัย
การบริหารวิชาการ

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 88-97
Structural divergence creates new functional features in alphavirus genomes
Creators: name: Madden, Emily A.
name: Vincent, Heather A.
name: Moorman, Nathaniel J.
name: Kutchko, Katrina M.
name: Laederach, Alain
name: Heise, Mark T.
name: Long, Kristin M.
name: Cisneros, Marta C. Cruz
name: Sanders, Wes
name: Plante, Kenneth S.
name: Morrison, Clayton
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Alphaviruses are mosquito-borne pathogens that cause human diseases ranging from debilitating arthritis to lethal encephalitis. Studies with Sindbis virus (SINV), which causes fever, rash, and arthralgia in humans, and Venezuelan equine encephalitis virus (VEEV), which causes encephalitis, have identified RNA structural elements that play key roles in replication and pathogenesis. However, a complete genomic structural profile has not been established for these viruses. We used the structural probing technique SHAPE-MaP to identify structured elements within the SINV and VEEV genomes. Our SHAPE-directed structural models recapitulate known RNA structures, while also identifying novel structural elements, including a new functional element in the nsP1 region of SINV whose disruption causes a defect in infectivity. Although RNA structural elements are important for multiple aspects of alphavirus biology, we found the majority of RNA structures were not conserved between SINV and VEEV. Our data suggest that alphavirus RNA genomes are highly divergent structurally despite similar genomic architecture and sequence conservation; still, RNA structural elements are critical to the viral life cycle. These findings reframe traditional assumptions about RNA structure and evolution: rather than structures being conserved, alphaviruses frequently evolve new structures that may shape interactions with host immune systems or co-evolve with viral proteins.
Two-Fold Homotopy of 2-Crossed Module Maps of Commutative Algebras
Creators: name: Akça, İ. İlker
name: Emir, Kadir
name: Martins, João Faria
Publisher: name: arXiv
Year: 2015
Subjects: subject: Category Theory (math.CT)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55U10 (principal), 18D05, 18D20, 55Q15 (secondary)

description: We address the homotopy theory of 2-crossed modules of commutative algebras. In particular, we define the concept of a 2-fold homotopy between a pair of 1-fold homotopies connecting 2-crossed module maps $\A \to \A'$. We also prove that if the domain 2-crossed module $\A$ is free up to order one (i.e. if the bottom algebra is a polynomial algebra) then we have a 2-groupoid of 2-crossed module maps $\A \to \A'$ and their homotopies and 2-fold homotopies.
description: 24 pages, to appear in Communications in Algebra
Workshop Sistemas Ambientais e Saúde Pública: Avaliação de Riscos e Estratégias de Adaptação às Alterações Climáticas
Creators: name: Mónica Rodrigues
name: Secretaria-Geral da Educação e Ciência
Publisher: name: Zenodo
Year: 2024

description: A Universidade de Coimbra (UC) promove, em colaboração com a Secretaria-Geral de Educação e Ciência (SGEC), no próximo dia 20 de setembro, pelas 9h00, um Workshop sobre "Sistemas Ambientais e Saúde Pública: Avaliação de Riscos e Estratégias de Adaptação às Alterações Climáticas”, em formato virtual e cujo programa se apresenta.

Este evento, de cariz multissetorial, reúne especialistas da Academia e de instituições relevantes da Comissão Europeia e de Portugal.

Os conteúdos programáticos do Workshop integram temas prementes sobre clima, saúde e adaptação às alterações climáticas.

· Alterações Climáticas: Passado, Presente e Futuro;

· Modelação dos Impactos das Alterações Climáticas na Saúde Humana: Riscos e Respostas;

· O Setor da Saúde e a Adaptação às Alterações Climáticas;

·  Alterações Climáticas, Vetores e Doenças Infeciosas;

·  Avaliação de Riscos Climáticos e Preparação dos Planos de Adaptação às Alterações Climáticas a Nível Local;

·  Roteiro Nacional para a Adaptação 2100;

·  Planeamento e Desenvolvimento Urbano Sustentável;

·  Estratégias do PMUS-Plano de Mobilidade Urbana Sustentável.

 

Os principais objetivos do Workshop são:

· Promover conhecimentos cientificamente sólidos sobre clima, saúde pública, sustentabilidade, resiliência e adaptação climáticas;

· Desenvolver e aprofundar conhecimentos sobre os efeitos das alterações climáticas e eventos extremos sobre a saúde;

· Fortalecer conhecimentos sobre o estabelecimento de sistemas de vigilância/monitorização e de informação à população e aos profissionais de saúde, assim como a integração da matéria - alterações climáticas - no planeamento em saúde;

· Promover conhecimentos especializados, sobre a avaliação de riscos climáticos, preparação e planeamento de respostas eficazes de adaptação às alterações climáticas;

· Capacitar para a promoção e integração de políticas de adaptação e programas relevantes em processos e estratégias de planeamento, em setores relevantes e a diferentes níveis;

· Compreender o território do ponto de vista do planeamento e desenvolvimento urbano sustentável;

· Aplicar instrumentos para a prossecução dos princípios patentes na legislação em matéria de mobilidade sustentável;

· Conhecer ações/medidas e boas práticas, que permitem a Portugal responder a exigentes desafios, como a prevenção dos riscos e resiliência às alterações climáticas.
Pochonia chlamydosporia Mitochondrial Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2013
Subjects: Genome sequencing
Monoisolate

description: The complete mitochondrial genome sequence of Pochonia chlamydosporia was determined. The conserved fungi mitochondrial genes were identified and the phylogenetic placement of Pochonia chlamydosporia was indicated. In this study, the evolution of mitochondrion size of fungi within Ascomycota was investigated.
Genetic control of alphavirus pathogenesis
Creators: name: Baxter, Victoria K.
name: Heise, Mark T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Alphaviruses, members of the positive-sense, single-stranded RNA virus family Togaviridae, represent a re-emerging public health concern worldwide as mosquito vectors expand into new geographic ranges. Members of the alphavirus genus tend to induce clinical disease characterized by rash, arthralgia, and arthritis (chikungunya virus, Ross River virus, and Semliki Forest virus) or encephalomyelitis (eastern equine encephalitis virus, western equine encephalitis virus, and Venezuelan equine encephalitis virus), though some patients who recover from the initial acute illness may develop long-term sequelae, regardless of the specific infecting virus. Studies examining the natural disease course in humans and experimental infection in cell culture and animal models reveal that host genetics play a major role in influencing susceptibility to infection and severity of clinical disease. Genome-wide genetic screens, including loss of function screens, microarrays, RNA-sequencing, and candidate gene studies, have further elucidated the role host genetics play in the response to virus infection, with the immune response being found in particular to majorly influence the outcome. This review describes the current knowledge of the mechanisms by which host genetic factors influence alphavirus pathogenesis and discusses emerging technologies that are poised to increase our understanding of the complex interplay between viral and host genetics on disease susceptibility and clinical outcome.
Geospiza fortis RefSeq Genome sequencing
Creators: name: BGI
Publisher: name: CNGB
Year: 2012
Subjects: RefSeq genome sequencing
Monoisolate

description: The medium ground finch (Geospiza fortis) is a seed-eating bird endemic to the Galapagos Islands of Ecuador. It inhabits subtropical or tropical dry forests and shrubland. The medium ground finch is one of "Darwin's finches"; a group of birds that evolved over a few million years from a single ancestral species into multiple species whose beak sizes and shapes are specialized for using different food resources. This species has been the subject of numerous evolutionary studies and is part of a project to sequence 10,000 vertebrate genomes (G10k).
Quantum simulation of energy transport with embedded Rydberg aggregates
Creators: name: Schönleber, D. W.
name: Eisfeld, A.
name: Genkin, M.
name: Whitlock, S.
name: Wüster, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We show that an array of ultracold Rydberg atoms embedded in a laser driven background gas can serve as an aggregate for simulating exciton dynamics and energy transport with a controlled environment. Spatial disorder and decoherence introduced by the interaction with the background gas atoms can be controlled by the laser parameters. This allows for an almost ideal realization of a Haken-Reineker-Strobl type model for energy transport. Physics can be monitored using the same mechanism that provides control over the environment. The degree of decoherence is traced back to information gained on the excitation location through the monitoring, turning the setup into an experimentally accessible model system for studying the effects of quantum measurements on the dynamics of a many-body quantum system.
description: 5 pages, 4 figures, 3 pages supp. inf
How misinformation reinforces the status of animals as food
Creators: name: Thew, David Anthony
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Humans and non-human animals are similar in many morally-relevant ways, however, the moral consideration we extend to humans, contrasted with that of animals, appears inconsistent. This inconsistency is made clear by the use of some animals for human consumption - on average, over 100 billion animals are slaughtered for human consumption every year. The extensive role that misinformation plays in the ongoing mistreatment of animals is under-explored. To remedy this deficit, this thesis examines how misinformation limits the moral consideration of some animals and reinforces their status as food. I begin by making an argument for increased moral consideration of animals, focusing on those animals that are commonly perceived as food in highly industrialized consumer cultures. I then explore misinformation in the context of animals through three lenses: (a) individual consumers, (b) animal-agricultural organizations, and (c) the media. Following this, I investigate the underlying mechanisms that reinforce the status of some animals as food. Consideration is first given to individual psychological mechanisms, before turning attention to the underlying socio-epistemological structures. I examine epistemic concepts of testimony, attention, trust, conformity, and expertise, to explain how and why false and misleading information takes hold, and ultimately reinforces the ongoing mistreatment of non-human animals.
A new approach toward geometrical concept of black hole thermodynamics
Creators: name: Hendi, S. H.
name: Panahiyan, S.
name: Panah, B. Elam
name: Momennia, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Motivated by the energy representation of Riemannian metric, in this paper we study different approaches toward the geometrical concept of black hole thermodynamics. We investigate thermodynamical Ricci scalar of Weinhold, Ruppeiner and Quevedo metrics and show that their number and location of divergences do not coincide with phase transition points arisen from heat capacity. Next, we introduce a new metric to solve these problems. We show that the denominator of the Ricci scalar of the new metric contains terms which coincide with different types of phase transitions. We elaborate the effectiveness of the new metric and shortcomings of the previous metrics with some examples. Furthermore, we find a characteristic behavior of the new thermodynamical Ricci scalar which enables one to distinguish two types of phase transitions. In addition, we generalize the new metric for the cases of more than two extensive parameters and show that in these cases the divergencies of thermodynamical Ricci scalar coincide with phase transition points of the heat capacity.
description: 13 pages with 7 figures, accepted in EPJC
Of mice and men: the host response to influenza virus infection
Creators: name: Pilzner, Carolin
name: Leist, Sarah R.
name: Kollmus, Heike
name: Heise, Mark
name: Schughart, Klaus
name: Geffers, Robert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Influenza virus (IV) infections represent a very serious public health problem. At present, no established biomarkers exist to support diagnosis for respiratory viral infections and more importantly for severe IV disease. Studies in animal models are extremely important to understand the biological, genetic, and environmental factors that contribute to severe IV disease and to validate biomarker candidates from human studies. However, mouse human cross-species comparisons are often compromised by the fact that animal studies concentrate on the infected lungs, whereas in humans almost all studies use peripheral blood from patients. In addition, human studies do not consider genetic background as variable although human populations are genetically very diverse. Therefore, in this study, we performed a cross-species gene expression study of the peripheral blood from human patients and from the highly genetically diverse Collaborative Cross (CC) mouse population after IV infection. Our results demonstrate that changes of gene expression in individual genes are highly similar in mice and humans. The top-regulated genes in humans were also differentially regulated in mice. We conclude that the mouse is a highly valuable in vivo model system to validate and to discover gene candidates which can be used as biomarkers in humans. Furthermore, mouse studies allow confirmation of findings in humans in a well-controlled experimental system adding enormous value to the understanding of expression and function of human candidate genes.
Detection of gene communities in multi-networks reveals cancer drivers
Creators: name: Cantini, Laura
name: Medico, Enzo
name: Fortunato, Santo
name: Caselle, Michele
Publisher: name: arXiv
Year: 2015
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Biological Physics (physics.bio-ph)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Physics and Society (physics.soc-ph)
subject: Genomics (q-bio.GN)
subject: FOS: Biological sciences
subject: FOS: Physical sciences
subject: 92D10

description: We propose a new multi-network-based strategy to integrate different layers of genomic information and use them in a coordinate way to identify driving cancer genes. The multi-networks that we consider combine transcription factor co-targeting, microRNA co-targeting, protein-protein interaction and gene co-expression networks. The rationale behind this choice is that gene co-expression and protein-protein interactions require a tight coregulation of the partners and that such a fine tuned regulation can be obtained only combining both the transcriptional and post-transcriptional layers of regulation. To extract the relevant biological information from the multi-network we studied its partition into communities. To this end we applied a consensus clustering algorithm based on state of art community detection methods. Even if our procedure is valid in principle for any pathology in this work we concentrate on gastric, lung, pancreas and colorectal cancer and identified from the enrichment analysis of the multi-network communities a set of candidate driver cancer genes. Some of them were already known oncogenes while a few are new. The combination of the different layers of information allowed us to extract from the multi-network indications on the regulatory pattern and functional role of both the already known and the new candidate driver genes.
description: minor modifications
Replication package for "Testing of Autonomous Driving Systems using Causal Discovery and Causal Inference"
Creators: name: CART
Publisher: name: figshare
Year: 2022
Subjects: subject: Computer Software
subject: FOS: Computer and information sciences
subject: 80309 Software Engineering

description: This is the replication package for "Testing of Autonomous Driving Systems using Causal Discovery and Causal Inference". It also includes the paper's appendix with the supplemental material.
การพัฒนารูปแบบการจัดการเรียนรู้วิทยาศาสตร์ สำหรับนักเรียนบนพื้นที่สูงภาคเหนือ
Creators: name: อุไรวรรณ หาญวงค์
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
Year: 2022
Subjects: รูปแบบการจัดการเรียนรู้วิทยาศาสตร์
การสืบเสาะทางวิทยาศาสตร์
อัตลักษณ์เชิงพื้นที่
ทักษะกระบวนการทางวิทยาศาสตร์
สมรรถนะการสื่อสาร

description: วารสารมหาวิทยาลัยศิลปากร, 42, 4, 98-111
Efficient all-optical control of solitons
Creators: name: Pickartz, Sabrina
name: Bandelow, Uwe
name: Amiranashvili, Shalva
Publisher: name: Weierstrass Institute
Year: 2016
Subjects: subject: Champion solitons
subject: All-optical switching
subject: Extreme events
subject: Soliton perturbation theory
subject: Event horizons
subject: 78A60
subject: 35Q60
subject: 70H11
subject: 42.65.-k
subject: 42.81.Dp
subject: 05.45.Yv
subject: 03.65.Nk

description: We consider the phenomenon of an optical soliton controlled (eg. amplified) by a much weaker second pulse which is efficiently scattered at the soliton. An important problem in this context is to quantify the small range of parameters at which the interaction takes place. This has been achieved by using adiabatic ODEs for the soliton characteristics, which is much faster than an empirical scan of the full propagation equations for all parameters in question.