cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Reinvigorating AMR resilience: leveraging CRISPR–Cas technology potentials to combat the 2024 WHO bacterial priority pathogens for enhanced global health security—a systematic review
Creators: name: Okesanya, Olalekan John
name: Ahmed, Mohamed Mustaf
name: Ogaya, Jerico Bautista
name: Amisu, Blessing Olawunmi
name: Ukoaka, Bonaventure Michael
name: Adigun, Olaniyi Abideen
name: Manirambona, Emery
name: Adebusuyi, Olakulehin
name: Othman, Zhinya Kawa
name: Oluwakemi, Olanegan Gloria
name: Ayando, Oluwaseunayo Deborah
name: Tan, Maria Ivy Rochelle S.
name: Idris, Nimat Bola
name: Kayode, Hassan Hakeem
name: Oso, Tolutope Adebimpe
name: Ahmed, Musa
name: Kouwenhoven, M. B. N.
name: Ibrahim, Adamu Muhammad
name: Lucero-Prisno, Don Eliseo
Publisher: name: figshare
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary material 1.
Convective hydrocodes for radial stellar pulsation. Physical and numerical formulation
Creators: name: Smolec, R.
name: Moskalik, P.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this paper we describe our convective hydrocodes for radial stellar pulsation. We adopt the Kuhfuss (1986) model of convection, reformulated for the use in stellar pulsation hydrocodes. Physical as well as numerical assumptions of the code are described in detail. Described tests show, that our models are numerically robust and reproduce basic observational constraints. We discuss the effects of different treatment of some quantities in other pulsation hydrocodes. Our most important finding concerns the treatment of the turbulent source function in convectively stable regions. In our code we allow for negative values of source function in convectively stable zones, which reflects negative buoyancy. However, some authors restrict the source term to non-negative values. We show that this assumption leads to very high turbulent energies in convectively stable regions. The effect looks like overshooting, but it is not, because turbulence is generated by pulsations. Also, turbulent elements do not carry kinetic nor thermal energy, into convectively stable layers. The range of this artificial overshooting (as we shall call it) is as large as 6 local pressure scale heights, leading to unphysical internal damping through the eddy-viscous forces, in deep, convectively stable parts of the star.
description: 43 pages, 12 figures; accepted for publication in Acta Astronomica
Additional file 1 of Defining expert opinion in clinical guidelines: insights from 98 scientific societies – a methodological study
Creators: name: Nagavci, Blin
name: Gáspár, Zsófia
name: Lakatos, Botond
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Protocol.
Deep Transfer Learning for Classification of Variable Sources
Creators: name: Kim, Dae-Won
name: Yeo, Doyeob
name: Bailer-Jones, Coryn A. L.
name: Lee, Giyoung
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Ongoing or upcoming surveys such as Gaia, ZTF, or LSST will observe light-curves of billons or more astronomical sources. This presents new challenges for identifying interesting and important types of variability. Collecting a sufficient number of labelled data for training is difficult, however, especially in the early stages of a new survey. Here we develop a single-band light-curve classifier based on deep neural networks, and use transfer learning to address the training data paucity problem by conveying knowledge from one dataset to another. First we train a neural network on 16 variability features extracted from the light-curves of OGLE and EROS-2 variables. We then optimize this model using a small set (e.g. 5%) of periodic variable light-curves from the ASAS dataset in order to transfer knowledge inferred from OGLE/EROS-2 to a new ASAS classifier. With this we achieve good classification results on ASAS, thereby showing that knowledge can be successfully transferred between datasets. We demonstrate similar transfer learning using Hipparcos and ASAS-SN data. We therefore find that it is not necessary to train a neural network from scratch for every new survey, but rather that transfer learning can be used even when only a small set of labelled data is available in the new survey.
description: 18 pages, 12 figures, 8 tables, Accepted for publication in Astronomy & Astrophysics
Additional file 2 of Defining expert opinion in clinical guidelines: insights from 98 scientific societies – a methodological study
Creators: name: Nagavci, Blin
name: Gáspár, Zsófia
name: Lakatos, Botond
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Included societies and details on guidance manuals and utilization of EO.
An essential oil blend significantly modulates immune responses and the cell cycle in human cell cultures
Creators: name: Xuesheng Han
name: Parker, Tory L.
name: Dorsett, Jeff
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: In the current study, we examined the biological activities of an essential oil blend (EOB) in validated human cell cultures, which model the molecular biology of autoimmune diseases and chronic inflammation. EOB is primarily composed of essential oils from wild orange, clove, cinnamon, eucalyptus, and rosemary. These disease models allow the measurement of changes in protein biomarkers induced by EOB treatment. Four T cell autoimmune disease systems and one skin cell system were used for biomarker analysis. Biomarkers levels were measured both before and after EOB treatment for statistic analysis. EOB exhibited significant effects on the levels of protein biomarkers that are critically involved in inflammation, immune modulation, and tissue remodeling processes. The overall inhibitory effect of EOB on these protein biomarkers suggests that it has anti-inflammatory and immune modulating properties. EOB also showed significant anti-proliferative activity against these cells. We next investigated the effect of EOB on genome-wide gene expression in a skin disease model. EOB significantly modulated global gene expression in the skin disease model. Further analysis showed that EOB robustly affected signaling pathways related to inflammation, immune function, and cell cycle control. This study documents the biological activities of EOB in complex human disease models, and indicates that EOB affects various biological and physiological processes in human cells. This study suggests that EOB possesses significant anti-inflammatory and immune modulating properties.
Characteristics of Interplanetary Discontinuities in the Inner Heliosphere Revealed by Parker Solar Probe
Creators: name: Liu, Y. Y.
name: Fu, H. S.
name: Cao, J. B.
name: Liu, C. M.
name: Wang, Z.
name: Guo, Z. Z.
name: Xu, Y.
name: Bale, S. D.
name: Kasper, J. C.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: We present a statistical analysis for the characteristics and spatial evolution of the interplanetary discontinuities (IDs) in the solar wind, from 0.13 to 0.9 au, by using the Parker Solar Probe measurements on Orbits 4 and 5. 3948 IDs have been collected, including 2511 rotational discontinuities (RDs) and 557 tangential discontinuities (TDs), with the remnant unidentified. The statistical results show that (1) the ID occurrence rate decreases from 200 events/day at 0.13 au to 1 events/day at 0.9 au, following a spatial scaling r-2.00, (2) the RD to TD ratio decreases quickly with the heliocentric distance, from 8 at r<0.3 au to 1 at r>0.4 au, (3) the magnetic field tends to rotate across the IDs, 45° for TDs and 30° for RDs in the pristine solar wind within 0.3 au, (4) a special subgroup of RDs exist within 0.3 au, characterized by small field rotation angles and parallel or antiparallel propagations to the background magnetic fields, (5) the TD thicknesses normalized by local ion inertial lengths (di) show no clear spatial scaling and generally range from 5 to 35 di, and the normalized RD thicknesses follow r-1.09 spatial scaling, (6) the outward (anti-sunward) propagating RDs predominate in all RDs, with the propagation speeds in the plasma rest frame proportional to r-1.03. This work could improve our understandings for the ID characteristics and evolutions and shed light on the study of the turbulent environment in the pristine solar wind.
description: Accepted by ApJS
title: Frontmatter, Table of Contents, Preface, Workshop Organization
Creators: name: Caprara, Alberto
name: Kontogiannis, Spyros
Publisher: name: Schloss Dagstuhl – Leibniz-Zentrum für Informatik
Year: 2011
Subjects: subject: Frontmatter
subject: Table of contents
subject: Preface
subject: Workshop Organization

description: Frontmatter, Table of contents, Preface, Workshop Organization
description: OASIcs, Vol. 20, 11th Workshop on Algorithmic Approaches for Transportation Modelling, Optimization, and Systems, pages i-ix
Energy dependence of phi meson production in central Pb+Pb collisions at sqrt(s_nn) = 6 to 17 GeV
Creators: name: Alt, C.
name: Anticic, T.
name: Baatar, B.
name: Barna, D.
name: Bartke, J.
name: Betev, L.
name: Bialkowska, H.
name: Blume, C.
name: Boimska, B.
name: Botje, M.
name: Bracinik, J.
name: Bramm, R.
name: Buncic, P.
name: Cerny, V.
name: Christakoglou, P.
name: Chung, P.
name: Chvala, O.
name: Cramer, J. G.
name: Csato, P.
name: Dinkelaker, P.
name: Eckardt, V.
name: Flierl, D.
name: Fodor, Z.
name: Foka, P.
name: Friese, V.
name: Gal, J.
name: Gazdzicki, M.
name: Genchev, V.
name: Georgopoulos, G.
name: Galadysz, E.
name: Grebieszkow, K.
name: Hegyi, S.
name: Hoehne, C.
name: Kadija, K.
name: Karev, A.
name: Kikola, D.
name: Kliemant, M.
name: Kniege, S.
name: Kolesnikov, V. I.
name: Kollegger, T.
name: Kornas, E.
name: Korus, R.
name: Kowalski, M.
name: Kraus, I.
name: Kreps, M.
name: Kresan, D.
name: Laszlo, A.
name: Lacey, R.
name: van Leeuwen, M.
name: Levai, P.
name: Litov, L.
name: Lungwitz, B.
name: Makariev, M.
name: Malakhov, A. I.
name: Mateev, M.
name: Melkumov, G. L.
name: Mischke, A.
name: Mitrovski, M.
name: Molnar, J.
name: Mrowczynski, St.
name: Nicolic, V.
name: Palla, G.
name: Panagiotou, A. D.
name: Panayotov, D.
name: Petridis, A.
name: Peryt, W.
name: Pikna, M.
name: Pluta, J.
name: Prindle, D.
name: Puehlhofer, F.
name: Renfordt, R.
name: Roland, C.
name: Roland, G.
name: Rybczynski, M.
name: Rybicki, A.
name: Sandoval, A.
name: Schmitz, N.
name: Schuster, T.
name: Seyboth, P.
name: Sikler, F.
name: Sitar, B.
name: Skrzypczak, E.
name: Slodkowski, M.
name: Stefanek, G.
name: Stock, R.
name: Strabel, C.
name: Stroebele, H.
name: Susa, T.
name: Szentpetery, I.
name: Sziklai, J.
name: Szuba, M.
name: Szymanski, P.
name: Trubnikov, V.
name: Varga, D.
name: Vassiliou, M.
name: Veres, G. I.
name: Vesztergombi, G.
name: Vranic, D.
name: Wetzler, A.
name: Walodarczyk, Z.
name: Yoo, I. K.
name: Zimanyi, J.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Phi meson production is studied by the NA49 Collaboration in central Pb+Pb collisions at 20A, 30A, 40A, 80A and 158A GeV beam energy. The data are compared with measurements at lower and higher energies and to microscopic and thermal models. The energy dependence of yields and spectral distributions is compatible with the assumption that partonic degrees of freedom set in at low SPS energies.
description: 18 pages, 12 figures, 6 tables
The rough fur (ruf) mutation in mice is an allele of myelin protein zero-like 3 (Mpzl3)
Creators: name: Palanza, Kenneth M.
name: Legairre A. Radden II
name: Rabah, Mohammed A.
name: Nguyen, Tu V.
name: Kohm, Audra C.
name: Connor, Malcolm E.
name: Ricci, Morgan M.
name: Jachius J. Stewart
name: Eragene, Sidney
name: King, Thomas R.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Background: The recessive rough fur mutation (ruf)―named for the unkempt, greasy appearance of the hair coat in homozygotes―has previously been mapped on mouse Chromosome 9. However, the assignment of ruf to a particular gene is needed to facilitate a complete molecular analysis of the mutant phenotype. Results: To establish a more refined location for ruf (as a basis for positional cloning) DNA isolated from a large backcross family was typed for microsatellite and single-nucleotide markers on Chromosome 9. This analysis restricted the location of ruf between sites that flank only four genes known to be expressed in skin, one of which―Mpzl3, for myelin protein zero-like 3―generates a similar hair phenotype in mice homozygous for engineered and spontaneous null-alleles. A cross between ruf mutants and mice heterozygous for the Mpzl3rc mutation (which controls a recessive phenotype called rough coat) produced offspring that displayed matted, damp-looking fur, indicating that ruf is a mutant allele of Mpzl3. However, sequence analysis of the Mpzl3 promoter, exons and splice junctions revealed no mutant-specific DNA defect. Conclusion: The results presented indicate that ruf is a mutant allele of Mpzl3. With a genetic assignment in hand, the rough fur variant can now be more fully characterized to advance our understanding of Mpzl3’s role in normal skin development and function, hepatic triglyceride synthesis, weight regulation, energy and glucose homeostasis; and to model-related human disorders.
Worldline master formulas for the dressed electron propagator, part 2: On-shell amplitudes
Creators: name: Ahmadiniaz, Naser
name: Guzman, Victor Miguel Banda
name: Bastianelli, Fiorenzo
name: Corradini, Olindo
name: Edwards, James P.
name: Schubert, Christian
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the first part of this series, we employed the second-order formalism and the ``symbol'' map to construct a particle path-integral representation of the electron propagator in a background electromagnetic field, suitable for open fermion-line calculations. Its main advantages are the avoidance of long products of Dirac matrices, and its ability to unify whole sets of Feynman diagrams related by permutation of photon legs along the fermion lines. We obtained a Bern-Kosower type master formula for the fermion propagator, dressed with $N$ photons, in terms of the ``$N$-photon kernel,'' where this kernel appears also in ``subleading'' terms involving only $N$-$1$ of the $N$ photons. In this sequel, we focus on the application of the formalism to the calculation of on-shell amplitudes and cross sections. Universal formulas are obtained for the fully polarised matrix elements of the fermion propagator dressed with an arbitrary number of photons, as well as for the corresponding spin-averaged cross sections. A major simplification of the on-shell case is that the subleading terms drop out, but we also pinpoint other, less obvious simplifications. We use integration by parts to achieve manifest transversality of these amplitudes at the integrand level and exploit this property using the spinor helicity technique. We give a simple proof of the vanishing of the matrix element for ``all $+$'' photon helicities in the massless case, and find a novel relation between the scalar and spinor spin-averaged cross sections in the massive case. Testing the formalism on the standard linear Compton scattering process, we find that it reproduces the known results with remarkable efficiency. Further applications and generalisations are pointed out.
description: 40 pages, 3 figures. Part 2 of a series started by arXiv:2004.01391 [hep-th]
Language and computer design for effective software systems
Creators: name: Lillich, Alan W.
Publisher: name: University of British Columbia
Year: 2010

description: This thesis describes two distinct, but mutually supportive, research projects. The first is the design and implementation of a high level language intended to be suitable for writing operating systems among other large software products. It provides facilities for the creation and control of asynchronous processes along with powerful data and "sequential" control structures. The second project is the design and implementation of a machine architecture which is a congenial host for modern block structured languages. This machine has several advantages compared to most of today's computers; code generation is simple, the object code is very compact and the machine is reasonably fast. Effective software systems are well designed, reliable, have "low" space-time products and are developed, maintained and used with a minimum amount of human effort. The work presented here is intended to be a viable first step towards the production of an environment for the production of effective software systems.
Effects of Magnetic Fields on the Diskoseismic Modes of Accreting Black Holes
Creators: name: Fu, Wen
name: Lai, Dong
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The origin of the rapid quasi-periodic variabilities observed in a number of accreting black hole X-ray binaries is not understood. It has been suggested that these variabilities are associated with diskoseismic oscillation modes of the black hole accretion disk. In particular, in a disk with no magnetic field, the so-called g-modes (inertial oscillations) can be self-trapped at the inner region of the disk due to general relativistic effects. Real accretion disks, however, are expected to be turbulent and contain appreciable magnetic fields. We show in this paper that even a weak magnetic field (with the magnetic energy much less than the thermal energy) can modify or "destroy" the self-trapping zone of disk g-modes, rendering their existence questionable in realistic black hole accretion disks. The so-called corrugation modes (c-modes) are also strongly affected when the poloidal field approaches equal-partition. On the other hand, acoustic oscillations (p-modes), which do not have vertical structure, are not affected qualitatively by the magnetic field, and therefore may survive in a turbulent, magnetic disk.
description: 21 pages, 5 figures, accepted for publication in ApJ
Quintessential Kination and Thermal Production of SUSY e-WIMPs
Creators: name: Gomez, M. E.
name: Lola, S.
name: Pallis, C.
name: Rodriguez-Quintero, J.
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The impact of a kination-dominated phase generated by a quintessential exponential model on the thermal abundance of Supersymmetric (SUSY) extremely Weekly Interacting Massive Particles (e-WIMPs) is investigated. For values of the quintessential energy-density parameter on the eve of nucleosynthesis close to its upper bound, we find that: (i) the gravitino constraint is totally evaded for unstable gravitinos; (ii) the thermal abundance of stable gravitinos is not sufficient to account for the cold dark matter of the universe; (iii) the thermal abundance of axinos can satisfy the cold dark matter constraint for values of the initial (``reheating'') temperature well above those required in the standard cosmology.
description: To appear in the proceedings of 4th International Workshop On The Dark Side Of The Universe (DSU 2008) 1-5 Jun 2008, Cairo, Egypt
الانزياح التركيبي في مرثيات الحنساء لأخيها صخر دراسة في أسلوبيات الإبداع وجماليات التشكيل اللغوي
Creators: name: ibrahim, ihab
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 470317
subject: Middle Eastern languages

description: موضوع هذه الدراسة هو دراسة الانزياح التركيبي -بصفته سمةً أسلوبيةً تمتازُ بها الكتابةُ الشعريةُ -في الغالب- ويلجأ إليها المبدعُ لإنتاج معانٍ شعرية غيرِ تلك التي تُنتجها الصياغة المعيارية؛ بُغية التمكين في نفس المتلقي لمعنى يقصده، أو زيادة التأثير في وجدانه- في مرثيات الخنساء لأخيها صخر، لما تعكسه هذه المرثيات من تجربة شعرية ووجدانية صادقة لا يُشكُّ في صدقها -بحسب ما تناقلته الأخبار حولها-؛ فكانت عنايةُ الدراسة متوجهةً إلى بيان مدى تأثير ذلك النوع من الانزياح في تمكين معاني الرثاء التي أبدعتها الشاعرة في نفس المتلقي لرثائها، وبيانِ إلى أي حدٍّ أسهم في نقل إحساسها بفجيعتها في فقد أخيها صخر إلى الآخرين.
Controllable inter-skyrmion attractions and resulting skyrmion-lattice structures in two-dimensional chiral magnets with in-plane anisotropy
Creators: name: Kameda, Mai
name: Koyama, Rio
name: Nakajima, Takuro
name: Kawaguchi, Yuki
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study inter-skyrmion interactions and stable spin configurations in a 2D chiral magnet with in-plane anisotropies of a tilted magnetic field and the magneto-crystalline anisotropy on a (011) thin film. We find that in both cases a small deformation of a skyrmion shape makes the inter-skyrmion interaction anisotropic, and that the skyrmions are weakly bounded along a certain direction due to an emergent attractive interaction. Furthermore, when the magneto-crystalline anisotropy is comparable to the Zeeman energy, skyrmions embedded in a uniform magnetization are tightly bound by creating a magnetic domain between them. The formation of the magnetic domain, and thus the strength of the inter-skyrmion interaction, can be controlled by the direction of an external magnetic field. The anisotropic interaction also affects the skyrmion alignment in the skyrmion crystal (SkX) phase. By employing the Monte Carlo simulation and the micromagnetic simulation, we obtain an elongated triangular lattice structure in the SkX phase. In particular, in the presence of a strong magneto-crystalline anisotropy, magnetic domains appear in the background of the lattice structure, and bimerons aligned on the domain walls form an elongated triangular lattice. We also find a parameter region that the SkX phase is stabilized due to the inter-skyrmion attraction.
description: 21 pages,17 figures
IMPLEMENTATION OF PEDAGOGICAL TECHNOLOGY FOR FUTURE MARKETOLOGIST LEADERSHIP COMPETENCE FORMATION INTO THE PRACTICE OF UNIVERSITY EDUCATION
Creators: name: Proshkin V.V.
name: Kazakevych, O.I.
Publisher: name: Colloquium-journal
Year: 2021
Subjects: pedagogical technology for leadership competence formation
technology for future marketologist leadership competence formation
leadership competence formation
university education.

description: The article describes the process of implementation of the developed pedagogical technology for future marketologist leadership competence formation into the practice of university education. The paper describes the directions in which the content of the educational process was modernized.
Additional file 3 of Defining expert opinion in clinical guidelines: insights from 98 scientific societies – a methodological study
Creators: name: Nagavci, Blin
name: Gáspár, Zsófia
name: Lakatos, Botond
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3. EO terminology.
Melaleuca (Melaleuca alternifolia) essential oil demonstrates tissue-remodeling and metabolism-modulating activities in human skin cells
Creators: name: Xuesheng Han
name: Parker, Tory L.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry

description: Melaleuca (Melaleuca alternifolia) essential oil (MEO), commonly known as tea tree oil, is popularly used in skincare products. In the current study, we investigated the biological activity of a commercially available MEO (with terpinen-4-ol as the major active component) in pre-inflamed human dermal fibroblasts, which were designed to simulate chronic inflammation. We analyzed the levels of seventeen biomarkers that are important in inflammation and tissue remodeling. Additionally, we studied the effect of MEO on genome-wide gene expression. MEO showed a robust antiproliferative activity against the cells. It also increased the levels of monocyte chemoattractant protein 1, an inflammatory chemokine, and several tissue remodeling molecules such as epidermal growth factor receptor, matrix metalloproteinase 1, and tissue inhibitor of metalloproteinase-1 and -2. It was also noted that MEO diversely modulated global gene expression. Furthermore, Ingenuity Pathway Analysis showed that MEO affects many important signaling pathways that are closely related to metabolism, which suggests its potential modulation of metabolism. The results provide an important evidence of the biological activity of MEO in human dermal fibroblasts. They also suggest that MEO plays useful roles in tissue remodeling and metabolism; however, further research is needed to explore the mechanisms underlying these actions.
Experimental Realization of Schumacher's Information Geometric Bell Inequality
Creators: name: Rezaei, Tahereh
name: Aslmarand, Shahabeddin M.
name: Snyder, Robert
name: Khajavi, Behzad
name: Alsing, Paul M.
name: Fanto, Michael
name: Doyeol
name: Ahn
name: Miller, Warner A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Quantum mechanics can produce correlations that are stronger than classically allowed. This stronger-than-classical correlation is the "fuel" for quantum computing. In 1991 Schumacher forwarded a beautiful geometric approach, analogous to the well-known result of Bell, to capture non-classicality of this correlation for a singlet state. He used well-established information distance defined on an ensemble of identically-prepared states. He calculated that for certain detector settings used to measure the entangled state, the resulting geometry violated a triangle inequality -- a violation that is not possible classically. This provided a novel information-based geometric Bell inequality in terms of a "covariance distance." Here we experimentally-reproduce his construction and demonstrate a definitive violation for a Bell state of two photons based on the usual spontaneous parametric down-conversion in a paired BBO crystal. The state we produced had a visibility of $V_{ad}=0.970$. We discuss generalizations to higher dimensional multipartite quantum states.
description: 10 pages, 4 figures
title: Frontmatter, Table of Contents, Preface, Committees, List of Authors
Creators: name: Simões, Alberto
name: Queirós, Ricardo
name: da Cruz, Daniela
Publisher: name: Schloss Dagstuhl – Leibniz-Zentrum für Informatik
Year: 2012
Subjects: subject: Frontmatter
subject: Table of Contents
subject: Preface
subject: Committees
subject: List of Authors

description: Frontmatter, Table of Contents, Preface, Committees, List of Authors
description: OASIcs, Vol. 21, 1st Symposium on Languages, Applications and Technologies, pages i-xvii
Single-frequency integrated laser on erbium-doped lithium niobate on insulator
Creators: name: Xiao, Zeyu
name: Wu, Kan
name: Cai, Minglu
name: Li, Tieying
name: Chen, Jianping
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The erbium-doped Lithium niobate on insulator (Er:LNOI) platform has great promise in the application of telecommunication, microwave photonics, and quantum photonics due to its excellent electro-optic, piezo-electric, nonlinear nature as well as the gain characteristics in the telecommunication C-band. Here, we report a single-frequency Er:LNOI integrated laser based on dual-cavity structure. Facilitated by the Vernier effect and gain competition, the single-frequency laser can operate stably at 1531-nm wavelength with a 1484-nm pump laser. The output laser has a power of 0.31 uW, a linewidth of 1.2 MHz, and a side mode suppression ratio (SMSR) of 31 dB. Our work allows the direct integration of this laser source with existing LNOI components and paves the way for a fully integrated LNOI system.
description: 4 pages, 4 figures
Excited-state spectroscopy using single-spin manipulation in diamond
Creators: name: Fuchs, G. D.
name: Dobrovitski, V. V.
name: Hanson, R.
name: Batra, A.
name: Weis, C. D.
name: Schenkel, T.
name: Awschalom, D. D.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We use single-spin resonant spectroscopy to study the spin structure in the orbital excited-state of a diamond nitrogen-vacancy center at room temperature. We find that the excited state spin levels have a zero-field splitting that is approximately half of the value of the ground state levels, a g-factor similar to the ground state value, and a hyperfine splitting ~20x larger than in the ground state. In addition, the width of the resonances reflects the electronic lifetime in the excited state. We also show that the spin-splitting can significantly differ between NV centers, likely due to the effects of local strain, which provides a pathway to control over the spin Hamiltonian and may be useful for quantum information processing.
description: 15 pages, 3 figures
PHYSIOLOGICAL EFFECTS AS A RESULT OF PROFESSIONAL BURNOUT SYNDROME
Creators: name: Horbatiuk Iryna Borysivna
name: Horbatiuk Inna Borysivna
Publisher: name: Colloquium-journal
Year: 2021
Subjects: burnout
physiological effects
body
stress.

description: Burnout is “a type of psychological distress-a chronic negative psychological condition that results as day-to-day work stressors take their toll” on educators (Roloff & Brown, 2011). Teachers who experience burnout have three categories of symptoms: exhaustion, depersonalization, and diminished personal achieve-ment. Exhaustion is experienced when a teacher feels as though all of his “emotional resources are used up” (Roloff & Brown, 2011). Depersonalization occurs when one separates himself from colleagues, family, and friends. Separation may manifest through a physical isolation or through distancing oneself emotionally (Rol-off & Brown, 2011). All burnt-out teachers feel a sense of decreased personal value and as though they are incompetent in their careers (Roloff & Brown, 2011). Like many other psychological conditions, burnout is caused by an interaction of environmental and physiological factors.
Etomidate decreases adrenal gland apoptosis and necrosis associated with hemorrhagic shock in a rat model (Rattus norvegicus)
Creators: name: Félix, Nuno M.
name: Goy-Thollot, Isabelle
name: Walton, Ronald S.
name: Borralho, Pedro M.
name: Pissara, Hugo
name: Matos, Ana S.
name: Rodrigues, Cecília M.P.
name: Niza, Maria M.R.E.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Purpose: Evaluate if etomidate modulates adrenal apoptosis and if this influences the development of critical illness-related corticosteroid insufficiency (CIRCI) in hemorrhagic shock (HS). Material and methods: Four groups of 16 male Wistar rats: G0 (control group anesthetized with isoflurane and mechanical ventilation), G1 (like G0, but with buprenorphine), G2 (like G1 with HS), and G3 (like G2 with etomidate 1 mg/kg, IV, before HS). HS induced by collecting 30% of blood volume. Resuscitation performed 90 min later with the collected blood and normal saline. Hemodynamic parameters, blood gas analysis, adrenocorticotropic hormone (ACTH), corticosterone (CS), and TNF-α, IL6, IL10 were determined at 0, 90, 150, and 240 min post-HS induction (at the corresponding time points in G0 and G1). Apoptosis and necrosis were determined by TUNEL and caspase-3 immunofluorescence and a necrosis score, respectively. Results: HS groups had significantly higher levels of apoptosis and necrosis than G1 and G0. Compared with G2, etomidate-treated animals had significantly lower levels of CS (compatible with CIRCI), PO2, PO2/FiO2, BE, HCO3, apoptosis, and necrosis and significantly higher cytokine levels. Conclusions: Etomidate was associated with CIRCI. HS was associated with adrenal gland apoptosis and necrosis. The latter were decreased by etomidate, possibly by both direct and indirect mechanisms.
THE MAIN ASPECTS OF PROFESSIONAL BURNOUT SYNDROME
Creators: name: Horbatiuk Iryna Borysivna
name: Horbatiuk Inna Borysivna
Publisher: name: Colloquium-journal
Year: 2021
Subjects: burnout
teacher
work
stress.

description: Teacher burnout is a serious psychological condition that affects the lives of thousands of highly effective teachers throughout the developed countries. An educator who is experiencing burnout has low morale, low self-esteem, and is physically exhausted (Roloff & Brown, 2011). Teacher morale directly correlates with stu-dent achievement the higher the teacher morale, the greater the student achievement (Raines, 2011). The emo-tional experience of a teacher sets the tone for a class. Teacher burnout is one of the most common reasons that effective teachers leave the profession (Roloff & Brown, 2011). If more energy were put into providing emo-tional support for effective educators, they would be far more likely to continue to teach and to share their passion and knowledge in the years to come. If a teacher is clinically depressed, anxious, or experiencing phys-ical illness, he will be more likely to retire early or to cease working to his capacity than if he is emotionally and physically well. With appropriate treatment and care, a teacher who is experiencing burnout, will be revi-talized and refocused on his work. Taking preventative measures will help educators to avoid the physical and emotional effects of prolonged stress and will provide them with the energy to continue to be successful teach-ers throughout their careers. Low morale is not only a problem for students; it is a problem for the faculty members themselves. In fact, burnout is not only a mental state, but a true psychological condition that nega-tively affects every aspect of a teacher’s life. However, few educators realize that significance of the condition. Policymakers and community members often are completely unaware of the physiological and psychological ramifications of teaching (Raines, 2011). For this reason, little research has been done to determine the best ways to improve teacher morale and to provide psychological support for chronic stress. In order to help edu-cational leaders to better serve their students and faculty, this paper seeks to answer the following question: what causes teacher burnout, how can teacher burnout be prevented, and how can burnout be healed so that teachers can return to a healthy and productive state?
NW-FVA Waldschutzinfo 2023-08
Creators: name: Hurling, Rainer
name: Rommerskirchen, Andreas
Publisher: name: Zenodo
Year: 2023

description: Waldschutzinfo 2023-08 der Nordwestdeutschen Forstlichen Versuchsanstalt (NW-FVA) in Göttingen zum Thema Aktuelles im Pflanzenschutz.
The NEVOD-EAS air-shower array
Creators: name: Amelchakov, M. B.
name: Barbashina, N. S.
name: Bogdanov, A. G.
name: Chiavassa, A.
name: Gromushkin, D. M.
name: Khokhlov, S. S.
name: Kindin, V. V.
name: Kokoulin, R. P.
name: Kompaniets, K. G.
name: Konovalova, A. Yu.
name: Ovchinnikov, V. V.
name: Pasyuk, N. A.
name: Petrukhin, A. A.
name: Shulzhenko, I. A.
name: Shutenko, V. V.
name: Yashin, I. I.
name: Yurin, K. O.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The Experimental complex NEVOD includes several different setups for studying various components of extensive air showers (EAS) in the energy range from 10^10 to 10^18 eV. The NEVOD-EAS array for detection of the EAS electron-photon component began its data taking in 2018. It is a distributed system of scintillation detectors installed over an area of about 10^4 m^2. A distinctive feature of this array is its cluster organization with different-altitude layout of the detecting elements. The main goal of the NEVOD-EAS array is to obtain an estimation of the primary particle energy for events measured by various detectors of the Experimental complex NEVOD. This paper describes the design, operation principles and data processing of the NEVOD-EAS array. The criteria for the event selection and the accuracy of the EAS parameters reconstruction obtained on the simulated events are discussed. The results of the preliminary analysis of experimental data obtained during a half-year operation are presented.
Excess noise depletion of a Bose-Einstein condensate in an optical cavity
Creators: name: Szirmai, G.
name: Nagy, D.
name: Domokos, P.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum fluctuations of a cavity field coupled into the motion of ultracold bosons can be strongly amplified by a mechanism analogous to the Petermann excess noise factor in lasers with unstable cavities. For a Bose-Einstein condensate in a stable optical resonator, the excess noise effect amounts to a significant depletion on long timescales.
description: 4 pages, 2 figures included in text
Síntesis de diagnóstico integral sobre Acceso Abierto y Datos Abiertos en Angola
Creators: name: United Nations Educational, Scientific and Cultural Organization
name: Ministério Do Ensino Superior, Ciência
name: Redalyc-Universidad Autónoma Del Estado De México
name: AmeliCA
name: Universidade Óscar Ribas
Publisher: name: Zenodo
Year: 2022
Subjects: Acceso Abierto
Angola
África
Datos Abiertos
políticas editoriales
internacionalización

description: Trabajo derivado del proyecto de colaboración entre Redalyc UAEM, AmeliCA, MESCTI y U. Óscar Ribas financiado por UNESCO para el desarrollo de una estrategia de Acceso Abierto en Angola. Vol. 10 de 38
Investigation of intrinsic dynamics of enzymes involved in metabolic pathways using coarse-grained normal mode analysis
Creators: name: Meeuwsen, Sarah M.
name: Hodac, An N.
name: Adams, Lauren M.
name: McMunn, Ryan D.
name: Anschutz, Maxwell S.
name: Carothers, Kari J.
name: Egdorf, Rachel E.
name: Hanneman, Peter M.
name: Kitzrow, Jonathan P.
name: Keonigsberg, Cynthia K.
name: Lopez-Martinez, Oscar
name: Matthew, Paul A.
name: Richter, Ethan H.
name: Schenk, Jonathan E.
name: Schmit, Heidi L.
name: Scott, Matthew A.
name: Volenec, Eva M.
name: Sanchita Hati
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Intrinsic dynamics of proteins are known to play important roles in their function. In particular, collective dynamics of a protein, which are defined by the protein’s overall architecture, are important in promoting the active site conformation that favors substrate binding and effective catalysis. The primary sequence of a protein, which determines its three-dimensional structure, encodes unique dynamics. The intrinsic dynamics of a protein actually link protein structure to its function. In the present study, coarse-grained normal mode analysis was performed to examine the intrinsic dynamic patterns of 24 different enzymes involved in primary metabolic pathways. We observed that each metabolic enzyme exhibits unique patterns of motions, which are conserved across multiple species and functionally relevant. Dynamic cross-correlation matrices (DCCMs) are visibly identical for a given enzyme family but significantly different from DCCMs of other protein families, reinforcing that proteins with similar function exhibit a similar pattern of motions. The present work also reasserted that correct identification of unknown proteins is possible based on their intrinsic mobility patterns.
Representing spatial experience and solving spatial problems in a simulated robot environment
Creators: name: Rowat, Peter Forbes
Publisher: name: University of British Columbia
Year: 2010

description: This thesis is concerned with spatial aspects of perception and action in a simple robot. To this end, the problem of designing a robot-controller for a robot in a simulated robot-environment system is considered. The environment is a two-dimensional tabletop with movable polygonal shapes on it. The robot has an eye which 'saes' an area of the tabletop centred on itself, with a resolution which decreases from the centre to the periphery. Algorithms are presented for simulating the motion and collision of two dimensional shapes in this environment. These algorithms use representations of shape both as a sequence, of boundary points and as a region in a digital image. A method is outlined for constructing and updating the world model of the robot as new visual input is received from the eye. It is proposed that, in the world model, the spatial problems of path-finding and object-moving be based on algorithms that find the skeleton of the shape of empty space and of the shape of the moved object. A new iterative algorithm for finding the skeleton, with the property that the skeleton of a connected shape is connected, is presented. This is applied to path-finding and simple object-moving problems. Finally, directions for future work, are outlined.
In vitro biological activities of Douglas fir essential oil in a human skin disease model
Creators: name: Xuesheng Han
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Although essential oils from Douglas fir are popular topical skincare products, research regarding their biological effects on human skin cells is scarce. Here, we studied the biological activity of a commercially available Douglas fir (Pseudotsuga menziesii) essential oil (DEO) in a human dermal fibroblast model of chronic inflammation and fibrosis induced by stimulation with cytokines. Chemical analysis of DEO indicated that its major chemical components (i.e. >5%) were beta-pinene (23%), sabinene (17%), terpinolene (14%), delta-3-carene (11%), and alpha-pinene (9%). We analyzed the effect of DEO on the levels of 17 important protein biomarkers associated with inflammation, immune system modulation, and tissue remodeling. DEO exhibited significant anti-proliferative activity in human fibroblasts. DEO also significantly inhibited the production of vascular cell adhesion molecule 1, collagen III, and plasminogen activator inhibitor 1. We also observed that DEO robustly modulated global gene expression levels in diverse ways. In particular, DEO affected the expression of genes involved in immune modulation and cancer signaling. This study provides the first evidence of biological activity of DEO in human dermal fibroblasts. Our results suggest that DEO may modulate immune responses and tumor signaling processes. Further research about the biological and pharmacological mechanisms of DEO action is recommended.
Borchers' Commutation Relations for Sectors with Braid Group Statistics in Low Dimensions
Creators: name: Mund, Jens
Publisher: name: arXiv
Year: 2008
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences
subject: 81T05

description: Borchers has shown that in a translation covariant vacuum representation of a theory of local observables with positive energy the following holds: The (Tomita) modular objects associated with the observable algebra of a fixed wedge region give rise to a representation of the subgroup of the Poincare group generated by the boosts and the reflection associated to the wedge, and the translations. We prove here that Borchers' theorem also holds in charged sectors with (possibly non-Abelian) braid group statistics in low space-time dimensions. Our result is a crucial step towards the Bisognano-Wichmann theorem for Plektons in d=3, namely that the mentioned modular objects generate a representation of the proper Poincare group, including a CPT operator. Our main assumptions are Haag duality of the observable algebra, and translation covariance with positive energy as well as finite statistics of the sector under consideration.
description: 15 pages
Additional file 1 of Nootropic foods in neurodegenerative diseases: mechanisms, challenges, and future
Creators: name: Nguyen, Le Anh Minh
name: Simons, Courtney Wayne
name: Thomas, Raymond
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy

description: Additional file 1. Figure S1. Flow chart of study selection in this review.