cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Deliberative capacity in post-Soviet transition : effects of colour revolutions, institutional design and international discourses on inter-cultural relations in Ukraine and Georgia
Creators: name: Salnykova, Anastasiya
Publisher: name: University of British Columbia
Year: 2015

description: This dissertation explores the issue of deliberative capacity in the context of inter-cultural relations in the democratizing post-Soviet states of Ukraine and Georgia. Specifically, it enquires about (1) the effect of deliberative capacity on inter-cultural relations, (2) the factors that affect deliberative capacity itself, and (3) the extent to which implementing deliberative democratic models is feasible in the context of post-Soviet Ukraine. It is argued that both ethnic studies and democratic transition studies significantly benefit from the application of the deliberative democracy approach. Based on the application of this approach, this work suggests three further arguments. First, deliberative capacity is the underlying feature of a multitude of ethnic mobilization theories. It suggests that instead of treating the different factors of ethnic conflict as competing, they can be looked at as each illuminating a different form or aspect of the deliberative capacity in a specific case. This dissertation suggests that such an overarching explanation simultaneously provides a more comprehensive and parsimonious story of ethnic radicalization while, usually, nuanced complexity and parsimony are at odds in theory building. Second, this study argues that a variety of factors that influence deliberative capacity affect its various components in different ways. It follows that factors of deliberative capacity are not necessarily entirely positive or negative. Instead, certain factors may create mixed effects on deliberative capacity by facilitating some of its features while jeopardizing the others. This is illustrated with the examples of such factors as colour revolutions, institutional design and the international national minority regime. Third, this dissertation draws attention to the existence of different kinds of deliberative systems that create very different contexts for politics and policies. This dissertation also explored the difficulties of applying the deliberative model in Ukraine and found that it is as difficult as it is necessary. These difficulties are nevertheless counterbalanced by a number of opportunities, and several deliberation precedents. Finally, the work formulates practical recommendations for national ethnic policy-makers, institutional designers, deliberation experiments developers, and international actors, that are expected to increase the level of deliberative capacity and thereby the level of inter-cultural peace.
Distributed Agile Software Development: A Review
Creators: name: Shrivastava, Suprika Vasudeva
name: Date, Hema
Publisher: name: arXiv
Year: 2010
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Distribution of software development is becoming more and more common in order to save the production cost and reduce the time to market. Large geographical distance, different time zones and cultural differences in distributed software development (DSD) leads to weak communication which adversely affects the project. Using agile practices for distributed development is also gaining momentum in various organizations to increase the quality and performance of the project. This paper explores the intersection of these two significant trends for software development i.e. DSD and agile. We discuss the challenges faced by geographically distributed agile teams and proven practices to address these issues, which will help in building a successful distributed team.
description: Submitted to Journal of Computer Science and Engineering, see http://sites.google.com/site/jcseuk/volume-1-issue-1-may-2010
Jaynes-Cummings model:Counter rotating effect on the vacuum Rabi splitting and atom-cavity dynamics
Creators: name: Zhang, Yu-Yu
name: Chen, Qing-Hu
name: Zhu, Shi-Yao
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: he effect of the counter-rotating terms in the Jaynes-Cummings model is investigated with an extended coherent-state approach. The counter-rotating terms greatly modify the vacuum Rabi splitting. Two peaks with different heights in the weak coupling regime and more than two peaks in the intermediate coupling regime are predicted. The collapses and revivals in the evolution of the atomic population inversion disappear in the intermediate coupling regime, but reappear in the strong coupling regime. This reappearance is similar to that under the rotating-wave approximation, attributed to the summation of periodic cosine functions of the evolution.
description: 4 pages, 3 figures
MERLIN H2020 Project: MERLIN.CIV.3.3.7.D2.6-MatchmakingContent
Creators: name: MERLIN Consortium
Publisher: name: Zenodo
Year: 2019

description: This document, D2.6 —  Matchmaking and I Bring the Idea content– is a deliverable of the MERLIN project, which is funded by the European Union's Horizon 2020 under Grant Agreement #780460, and has been prepared by taking into account the template of the "Guidelines on FAIR Data Management in Horizon 2020" and the "Fact Sheet: Open Access in Horizon 2020".

Merlin aims to foster and accelerate the transfer of knowledge from the projects funded in FP7 and H2020, be it on the form of license agreement, patent or ideally, spinoff or startup to directly exploit them, by organising practical hands-on workshops; meet ups with potential partners, customers and investors; and by attending scientific conferences to reach a wider public. The programme will equip participants with knowledge, skills and a network to generate market-led business models to unlock potential and accelerate this journey.

The purpose of this deliverable is to provide the content and structure of the two kind of meetups - Matchmaking and I Bring the Idea content - that will be organized and delivered by all the members
description: File Naming Convention: MERLIN.PartnerName.CSACode.DatasetName
NEW OPPORTUNITIES TO LEARN A FOREIGN LANGUAGE IN UZBEKISTAN
Creators: name: Orzikulova, Nigina
name: Rahmonova, Madina
name: Jorayeva, Nafisa
name: Azizova, Aisha
name: Khonsaidova, Maktuba
Publisher: name: Zenodo
Year: 2025

description: The article analyzes the introduction of teaching foreign languages in Uzbekistan, the processes associated with new opportunities for teaching languages, as well as the problems of training specialists in foreign languages on the basis of archival data and government decisions.
Stress intensity factor due to screw dislocations. from Meso-scale dislocations and friction of shape-complementary soft interfaces
Creators: name: He, Zhenping
name: Liu, Zezhou
name: Li, Meng
name: Hui, Chung-Yuen
name: Jagota, Anand
Publisher: name: The Royal Society
Year: 2021

description: Stress intensity factor due to applied screw dislocation density for a periodic array of cracks
Centrality dependence of proton and antiproton spectra in Pb+Pb collisions at 40A GeV and 158A GeV measured at the CERN SPS
Creators: name: Anticic, T.
name: Baatar, B.
name: Barna, D.
name: Bartke, J.
name: Beck, H.
name: Betev, L.
name: Bialkowska, H.
name: Blume, C.
name: Bogusz, M.
name: Boimska, B.
name: Book, J.
name: Botje, M.
name: Buncic, P.
name: Cetner, T.
name: Christakoglou, P.
name: Chung, P.
name: Chvala, O.
name: Cramer, J. G.
name: Eckardt, V.
name: Fodor, Z.
name: Foka, P.
name: Friese, V.
name: Gazdzicki, M.
name: Grebieszkow, K.
name: Höhne, C.
name: Kadija, K.
name: Karev, A.
name: Kolesnikov, V. I.
name: Kowalski, M.
name: Kresan, D.
name: Laszlo, A.
name: Lacey, R.
name: van Leeuwen, M.
name: Mackowiak, M.
name: Makariev, M.
name: Malakhov, A. I.
name: Mateev, M.
name: Melkumov, G. L.
name: Mitrovski, M.
name: Mrowczynski, S.
name: Nicolic, V.
name: Pálla, G.
name: Panagiotou, A. D.
name: Peryt, W.
name: Pluta, J.
name: Prindle, D.
name: Pühlhofer, F.
name: Renfordt, R.
name: Roland, C.
name: Roland, G.
name: Rybczyński, M.
name: Rybicki, A.
name: Sandoval, A.
name: Schmitz, N.
name: Schuster, T.
name: Seyboth, P.
name: Sikler, F.
name: Skrzypczak, E.
name: Slodkowski, M.
name: Stefanek, G.
name: Stock, R.
name: Strobele, H.
name: Susa, T.
name: Szuba, M.
name: Utvic, M.
name: Varga, D.
name: Veres, M. Vassiliou G. I.
name: Vesztergombi, G.
name: Vranic, D.
name: Włodarczyk, Z.
name: Wojtaszek-Szwarc, A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The yields of (anti-)protons were measured by the NA49 Collaboration in centrality selected Pb+Pb collisions at 40A GeV and 158A GeV. Particle identification was obtained in the laboratory momentum range from 5 to 63 GeV/c by the measurement of the energy loss dE/dx in the TPC detector gas. The corresponding rapidity coverage extends 1.6 units from mid-rapidity into the forward hemisphere. Transverse mass spectra, the rapidity dependences of the average transverse mass, and rapidity density distributions were studied as a function of collision centrality. The values of the average transverse mass as well as the midrapidity yields of protons when normalized to the number of wounded nucleons show only modest centrality dependences. In contrast, the shape of the rapidity distribution changes significantly with collision centrality, especially at 40A GeV. The experimental results are compared to calculations of the HSD and UrQMD transport models.
description: 25 pages, 12 figures, submitted to PRC
Spectroscopy Unveils the Complex Nature of Terzan 5
Creators: name: Origlia, L.
name: Rich, R. M.
name: Ferraro, F. R.
name: Lanzoni, B.
name: Bellazzini, M.
name: Dalessandro, E.
name: Mucciarelli, A.
name: Valenti, E.
name: Beccari, G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the chemical abundance analysis of 33 red giant stars belonging to the complex stellar system Terzan 5. We confirm the discovery of two stellar populations (Ferraro et al. 2009, Nature, 462,483) with distinct iron abundances: a relatively metal-poor component with [Fe/H]=-0.25 +/- 0.07 r.m.s., and another component with [Fe/H]=+0.27 +/- 0.04 r.m.s., exceeding in metallicity any known Galactic globular cluster. The two populations also show different [alpha/Fe] abundance ratios. The metal-poor component has an average [alpha/Fe]=+0.34 +/- 0.06 r.m.s., consistent with the canonical scenario for rapid enrichment by core collapse supernovae (SNe). The metal-rich component has [alpha/Fe]=+0.03 +/-i 0.04 r.m.s., suggesting that the gas from which it formed was polluted by both type II and type Ia SNe on a longer timescale. Neither of the two populations shows evidence of the [Al/Fe] over [O/Fe] anti-correlation, that is typically observed in Galactic globular clusters. Because these chemical abundance patterns are unique, we propose that Terzan 5 is not a true globular cluster, but a stellar system with a much more complex history of star formation and chemical enrichment.
MPEC 2023-H195 : 2022 HX3
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Solvent and Substituent Effects on the Conversion of 4-methoxypyridines to N-Methyl-4-pyridones
Creators: name: Yi, Xiao
name: Chen, Jing
name: Xu, Xiuling
name: Ma, Yongmin
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Molecular Biology
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Computational Biology

description: In the reaction of 4-methoxypyridine derivatives with alkyl iodides in the presence or absence of solvent, not only the pyridinium ions but also the related 1-methylpyridones are produced. The presence of solvent favours the formation of the 1-methylpyridone. Electron withdrawing groups on the pyridine ring also favours this conversion. A possible mechanism is presented.
Dependence of transport on adatom location for armchair-edge graphene nanoribbons
Creators: name: Chen, Xiongwen
name: Song, Kehui
name: Zhou, Benhu
name: Wang, Haiyan
name: Zhou, Guanghui
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the transport property for armchair-edge graphene nanoribbons (AGNRs) with an adatom coupling to a semi-infinite quantum wire. Using the nonequilibrium Green's function approach with tight-binding approximation, we demonstrate that the tunneling current through the system is sensitively dependent on both the AGNR width and adatom location. Interestingly, when the adatom locates onto a carbon atom in the 3$j$th chain from the edge of a metallic AGNR, the system shows a transmission gap accompanied by a threshold voltage in $I-V$ curve like a semiconducting AGNR. This effect may be useful in scanning tunneling microscopy experimental characterization on graphene samples.
description: 3 pages, 4 figures
An XMM-Newton spectral survey of 12 micron selected galaxies. II. Implications for AGN selection and unification
Creators: name: Brightman, Murray
name: Nandra, Kirpal
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present a multi-waveband analysis of a 126 galaxy sub-sample of the 12 micron galaxy sample (12MGS), for which we have carried out a detailed X-ray spectral analysis of in a previous paper. We present optical activity classes and we characterise these by their X-ray, 12 um and [OIII] luminosities and by their X-ray spectral properties. Our most interesting results are: Seyfert (Sy) 1s and Sy 2s show significantly different LX distributions from each other; Sy 2s with a detection of an HBLR show a significantly higher LX than those without a detection; Sy 1s also present a significantly different L(12um) distribution from both Sy1.2-1.9s and Sy 2s; the Sy 2 fraction decreases towards high LX; X-ray indications of AGN power agree well with the optical classifications; There is X-ray evidence for the presence of an AGN in 17% of HII/AGN composites and 40% of LINERs; we advocate the use of a LX >10^41 erg/s in the X-ray selection of AGN, which gives a contamination rate of only 3% from star-forming galaxies; Sy 1s and Sy 2 have the same intrinsic Γ; in 24% of cases the absorption measured in X-rays does not correspond directly with that implied in the optical band from the visibility of the BLRs; the obscured fraction in AGN is a strong function of LX peaking at 10^42 erg/s; The average obscured and Compton thick fractions for this sample are 62\pm5% and 20\pm4% respectively, which are higher than hard X-ray and optically selected samples; we assess the use of the T ratio (FX/F[OIII]) for selecting Compton thick candidates. We conclude here that this quantity can often be unreliable due uncertainties in the extinction corrections to the [OIII] flux. These results have important impacts on AGN selection and unification and the results from the 12MGS are particularly useful as a local analogue to z=1 24 um samples.
description: 27 pages, 12 figures, accepted for publication by MNRAS
Representation of States on Effect-Tribes and Effect Algebras by Integrals
Creators: name: Dvurečenskij, Anatolij
Publisher: name: arXiv
Year: 2010
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 81P15, 03G12, 03B50

description: We describe $σ$-additive states on effect-tribes by integrals. Effect-tribes are monotone $σ$-complete effect algebras of functions where operations are defined by points. Then we show that every state on an effect algebra is an integral through a Borel regular probability measure. Finally, we show that every $σ$-convex combination of extremal states on a monotone $σ$-complete effect algebra is a Jauch-Piron state.
description: 20 pages
Frothing properties of fatty acid collectors
Creators: name: Atrafi, Avishan
Publisher: name: University of British Columbia
Year: 2015

description: The gas dispersion and foaming properties of aqueous solutions of fatty acids of different hydrocarbon chain lengths were assessed through measurements of bubble size distributions, gas hold-up, foam volume and growth rate. The adsorption behavior of the tested fatty acids at the gas-solution interface was assessed and the results were supplemented by measurements of the partition of each surfactant between the bulk solution and foam phase as a result of continuous aeration. Two mechanisms of gas dispersion were identified depending on the pH and speciation of the tested solutions. Solutions of long chain fatty acids containing colloidal precipitates at low pH exhibited low surface tensions, and only a small decrease in bubble sizes was observed for such solutions compared to bubble sizes measured in water. This relatively small change in bubble sizes could theoretically be predicted based only on the corresponding change in the surface tension of the solutions. In contrast, true solutions of long chain fatty acids affected bubble sizes to a much greater extent even though their surface tension values were higher and in some cases comparable to the surface tension of water. A combination of the surface tension and surface tension gradient effects was found to be operative in this case. Experimental results strongly suggested that the associated acid species were more surface-active and more capable of reducing bubble sizes than the dissociated carboxylate anion. The ability of the surfactants to quickly generate a large foam volume was found to be a strong function of the chain length. Although bubble size measurements in bulk solution pointed towards similar gas dispersing abilities of fatty acids of different chain lengths, their foamabilities under the same conditions were remarkably enhanced by increasing chain length. Creation of large volumes of persistent foam was correlated with strong tendency to partition into the foam phase. Overall, the gas dispersing properties of fatty acids were comparable to those of a weak frother such as methyl isobutyl carbinol (MIBC), while only the foaming capabilities of hexanoate were similar to those of MIBC. Longer chain fatty acids were much stronger foaming agents than MIBC.
On properties not inherited by monoids from their Schutzenberger groups
Creators: name: Gray, Robert
name: Malheiro, António
name: Pride, Stephen J
Publisher: name: arXiv
Year: 2010
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20M50, 20M05, 68Q42

description: We give an example of a monoid with finitely many left and right ideals, all of whose Schutzenberger groups are presentable by finite complete rewriting systems, and so each have finite derivation type, but such that the monoid itself does not have finite derivation type, and therefore does not admit a presentation by a finite complete rewriting system. The example also serves as a counterexample to several other natural questions regarding complete rewriting systems and finite derivation type. Specifically it allows us to construct two finitely generated monoids M and N with isometric Cayley graphs, where N has finite derivation type (respectively, admits a presentation by a finite complete rewriting system) but M does not. This contrasts with the case of finitely generated groups for which finite derivation type is known to be a quasi-isometry invariant. The same example is also used to show that neither of these two properties is preserved under finite Green index extensions.
description: 18 pages
Markov entropy decomposition: a variational dual for quantum belief propagation
Creators: name: Poulin, David
name: Hastings, Matthew B.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a lower bound for the free energy of a quantum many-body system at finite temperature. This lower bound is expressed as a convex optimization problem with linear constraints, and is derived using strong subadditivity of von Neumann entropy and a relaxation of the consistency condition of local density operators. The dual to this minimization problem leads to a set of quantum belief propagation equations, thus providing a firm theoretical foundation to that approach. The minimization problem is numerically tractable, and we find good agreement with quantum Monte Carlo for the spin-half Heisenberg anti-ferromagnet in two dimensions. This lower bound complements other variational upper bounds. We discuss applications to Hamiltonian complexity theory and give a generalization of the structure theorem of Hayden, Jozsa, Petz and Winter to trees in an appendix.
Implementation and analysis of a bubble packing method for surface mesh generation
Creators: name: Saini, Saurabh
Publisher: name: No Publisher Supplied
Year: 2019

description: This thesis presents an implementation and analysis of the bubble packing method used for surface mesh generation. The bubble packing method was first proposed by Dr Kenji Shimada in 1993 in his PhD thesis. The method generates a triangle mesh, a set of connected triangles that satisfy requirements of well-shaped triangles, compatible with a given domain, and with controlled node spacing or triangle size. This type of mesh is mainly used in finite element analysis and utilised in many simulations. There has not been much research on the bubble packing method since the 90s. The goal of this thesis is to implement and analyse the bubble packing method in order to create a path for possible future improvements and applicability of this approach to meshing. The approach in this method consists of three stages: placing nodes by spatial subdivision, moving nodes on proximity-based repulsive/attractive internode forces and finally, after nodes reach the required stability, connect nodes to create a set of well-shaped triangles by Delaunay triangulation. The first two stages, placement and movement of nodes, are carried out by placing a spherical region around each node and packing the spheres in the given domain as tightly as possible. The original description of the bubble packing method lacks many important details that are necessary for its practical implementation. This thesis also presents approaches to fill the gaps in the original algorithm so that it can be implemented.
Prospects of polarized fixed target Drell-Yan experiments
Creators: name: Liu, Ming X.
name: Jiang, Xiaodong
name: Crabb, Donald G.
name: Chen, Jian-ping
name: Bai, Mei
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: It has been proposed that the Siverse transverse single spin asymmetry in Drell-Yan production in transversely polarized p+p collisions would have an opposite sign compared to what has been observed in the polarized Semi-Inclusive Deep Inelastic Scattering (SIDIS) experiments. Experimental confirmation or disproval of this prediction would provide a new fundamental test of QCD and shed new light on our theoretical understanding of the transverse spin physics phenomena. We discuss the prospects and physics sensitivities of polarized fixed target Drell-Yan experiments that could utilize the existing proton and other hadron beams at Fermilab, and polarized proton beams at RHIC with a polarized solid proton and/or neutron target option. We show that if realized, the new experiments would provide critical measurements of not only the sign change (or not) of Sivers functions, but also the information of quark and antiquark's Sivers distributions over a wide kinematic range.
description: 8 pages, to appear in the proceedings of the 19th International Spin Physics Symposium (SPIN 2010), Julich, Germany, Sep 27- Oct 2, 2010
Velocity fields in and around sunspots at the highest resolution
Creators: name: Denker, Carsten
name: Verma, Meetu
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The flows in and around sunspots are rich in detail. Starting with the Evershed flow along low-lying flow channels, which are cospatial with the horizontal penumbral magnetic fields, Evershed clouds may continue this motion at the periphery of the sunspot as moving magnetic features in the sunspot moat. Besides these well-ordered flows, peculiar motions are found in complex sunspots, where they contribute to the build-up or relaxation of magnetic shear. In principle, the three-dimensional structure of these velocity fields can be captured. The line-of-sight component of the velocity vector is accessible with spectroscopic measurements, whereas local correlation or feature tracking techniques provide the means to assess horizontal proper motions. The next generation of ground-based solar telescopes will provide spectropolarimetric data resolving solar fine structure with sizes below 50 km. Thus, these new telescopes with advanced post-focus instruments act as a "zoom lens" to study the intricate surface flows associated with sunspots. Accompanied by "wide-angle" observations from space, we have now the opportunity to describe sunspots as a system. This review reports recent findings related to flows in and around sunspots and highlights the role of advanced instrumentation in the discovery process.
description: 6 pages, 1 figure, to be published in "Physics of Sun and star spots", Proc. IAU Symp. 273, D.P. Choudhary and K.G. Strassmeier (eds.)
Immune infiltration in ovarian cancer and its significance in chemotherapy
Creators: name: Lo, Charlotte Sum-Yee
Publisher: name: University of British Columbia
Year: 2015

description: High grade serous carcinoma (HGSC), the most commonly diagnosed ovarian cancer subtype, is often presented as late stage disease with high recurrence rates, thus contributing to poor prognosis. Despite poor survival outcomes, the presence of tumour-infiltrating lymphocytes (TIL) in primary, untreated tumours is associated with increased survival. However, little is known about the phenotype and composition of TIL subsets in HGSC patients following treatment. In this thesis, we investigated the functional phenotype of TIL and the changes in immune composition in tumours over the course of chemotherapy. In Chapter 2, we investigated the association of cytotoxic TIL with the presence of apoptotic tumour cells in primary tumours. By immunohistochemistry (IHC), we found that the majority of the CD8⁺T cells lack cytotoxic Ganzyme B and that the presence of both CD8⁺ and Granzyme B⁺TIL were not associated with the presence of apoptotic cleaved caspase-3⁺ tumour cells. In Chapter 3, we investigated the composition of TIL subsets in HGSC following neoadjuvant chemotherapy in matching pre- and post-chemotherapy tumour samples. By IHC, we found an increased density of intraepithelial T cells, CD20⁺B cells, and TIA-1⁺ and PD-1⁺TIL. In contrast, no significant change was found in the density of intraepithelial Granzyme B⁺TIL, FoxP3⁺T cells, or CD68⁺ macrophages. Patients with high CD8⁺TIL density following chemotherapy showed prolonged survival. Thus, we found the immune response to cancer is dynamic, and TIL populations change during the course of treatment. The results from this study indicate chemotherapy can alter the immunologic microenvironment in which tumour prior to chemotherapy lacking cytotoxic T cells can have increased infiltration of cytotoxic T cells and B cells, as well as PD-1⁺TIL. This study indicates the increased TIL infiltration following chemotherapy could be further enhanced with immunotherapies, such as tumour-specific vaccines and immune modulators (PD-1 blockade), to eradicate remaining tumour cells and reduce recurrences in HGSC. This work contributes to a better understanding of the effects of chemotherapy on TIL and this can lead to a more strategic development of immunotherapies in order to harness the anti-tumour immune response and mitigate immunosuppression against cancer.
Towards a unified definition of solar limb during central eclipses and daily transits
Creators: name: Sigismondi, Costantino
name: Raponi, Andrea
name: Bazin, Cyril
name: Nugent, Richard
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The diameter of the Sun has been measured using Baily's beads during central eclipses, observed with portable telescopes. A blend of tiny emission lines produced in the first several hundred kilometers above the photosphere gives a light signal which prolonges the light curves of the beads. The simple criterion of light OFF/ON adopted in the previous approaches to define the timing of photosphere's disappearance/reappearance is modified. The technique of the limb darkening function reconstruction from the Baily's beads light curves is introduced here.
description: 9 pages, 6 figures, Proc. of the 2nd Galileo-Xu Guangqi Meeting, Ventimiglia - Villa Hanbury, Italy, 11-16 July 2010
A remark on Dickey's stabilizing chain
Creators: name: Svinin, Andrei K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We observe that Dickey's stabilizing chain can be naturally included into two-dimensional chain of infinitely many copies of equations of KP hierarchy.
description: 2 pages
The 198Au beta-half-life in the metal Au revisited
Creators: name: Fortak, K.
name: Kunz, R.
name: Gialanella, L.
name: Becker, H. -W.
name: Meijer, J.
name: Strieder, F.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The half-life of the beta-decay of 198Au has been measured for room temperature and 12 K. The resulting values of T(RT) = 2.684 +- 0.004 d and T(12 K) = 2.687 +- 0.005 d agree well within statistical uncertainties. An evidence for a temperature dependence of the half-life was not observed.
description: accepted for publication in Eur. Phys. J. A
Sortenwahl bei Sommerackerbohnen
Creators: name: Roth, Philipp
Publisher: name: Zenodo
Year: 2022
Subjects: Ackerbohnen
legumes

description: Unter den gängigen Körnerleguminosen haben Ackerbohnen die höchsten Ansprüche an Boden­güte und Wasserverfügbarkeit. Liegen passende Standortbedingungen vor, kann mithilfe einer gezielten Sortenwahl der Grundstein für einen erfolgreichen Ackerbohnenanbau gelegt werden. Insgesamt gibt es zwar eine geringe Auswahl an Ackerbohnensorten, dennoch sind in den letzten Jahren in Deutschland einige neue Sorten mit unterschiedlichen Eigenschaften auf den Markt gekommen. Die wesentlichen Unterschiede der in Deutschland angebauten Sorten liegen im Kornertragspotential und Rohproteingehalt, den antinutritiven Inhaltsstoffen, der Tausend­kornmasse (TKM) sowie in gewissem Maße der Krankheitsanfälligkeit. Of all the common legumes, field beans are the most demanding in terms of soil quality and water availability. If the site conditions are suitable, the foundation for successful field bean cultivation can be laid with the help of a targeted selection of varieties. Although there is a small overall selection of field bean varieties, a number of new varieties with different characteristics have come onto the market in Germany in recent years. The main differences between the varieties grown in Germany lie in their grain yield potential and crude protein content, the antinutritional ingredients, the thousand grain mass (TKM) as well as to a certain extent the disease incidence.
Picard satellite for solar astrometry
Creators: name: Sigismondi, Costantino
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The Picard solar satellite has been launched on June 15, 2010. This mission is dedicated to the measurement of the solar diameter with an expected accuracy of milliarcseconds of arc. The radiometer onboard is to measure the total solar irradiance. The final goal is the evaluation of the W, the logarithmic ratio of radius and luminosity. This parameter will help the climatologists to recover past values of the solar luminosity when the radius is available from ancient eclipses data.
description: 5 pages, 2 figures, Proc. 2nd Galileo-Xu Guangqi Meeting, Ventimiglia - Villa Hanbury, Italy, 11-16 July 2010
The timing and genesis of the Blackwater gold-silver deposit, central British Columbia : constraints from geology, geochronology and stable isotopes
Creators: name: Looby, Erin Lynn
Publisher: name: University of British Columbia
Year: 2015

description: The Blackwater Au-Ag deposit of central British Columbia is hosted by a lithic-rich, latite lapilli tuff and felsic volcanic rock sequence. U/Pb zircon geochronology shows that these two volcanic rock sequences are Late-Cretaceous, and were deposited at ca. 73.5 and 73.1 Ma, respectively. These host rocks overlie plagioclase to hornblende porphyritic andesite lava flows, mudstone, chert and conglomerate. A monzonite intruded the western portion of the deposit. Felsic dykes or sills are inferred to have intruded felsic volcanic rocks at ca. 68 Ma. A post-mineralization, dacitic sill intruded contacts between sedimentary rocks and lithic-rich, latite tuffs in the south of the Blackwater deposit at ca. 53 Ma. High temperature (>300⁰C), biotite-sericite-sulfide, actinolite-sulfide and garnet-sulfide assemblages alter rocks at the deposit’s perimeter. Low temperature (250-350⁰C), Au-mineralizing fluids precipitated the early main-stage green sericite-quartz-pyrite and the late main-stage green sericite-chlorite-quartz-base metal sulfide assemblages located in the deposit’s centre. ⁴⁰Ar/³⁹Ar geochronology suggests that high temperature alteration minerals precipitated prior to Au-mineralization, between ~68-64 Ma, and that Au-mineralization took place at ca. 65.6-63.9 Ma. The ⁴⁰Ar/³⁹Ar systematics of biotite were reset at ca. 59 Ma during a thermal event. High temperature, barren alteration is attributed to fluids with stable isotope compositions distinct from those that precipitated low temperature alteration. High temperature alteration minerals are enriched in ¹⁸O relative to primary magmatic waters (δ¹⁸OH₂O = 8.9-12.6‰) and have variable δD values (δD =-93.9 to -66.1‰). This, in conjunction with depleted, sedimentary δ³⁴S values (δ³⁴Smineral =-17.7 to -7.7‰) suggests a combination of exchanged meteoric waters, sedimentary formation and/or magmatic fluid sources. A component of magmatic fluids ± evolved meteoric fluids is inferred for low temperature, Au mineralizing fluids. Calculated stable isotope compositions of fluids in equilibrium with green sericite (δ¹⁸O =6.6 - 7.1‰, δD = -79.2 to -62.9‰) plot within the primary magmatic water field while isotopic compositions of associated sulfides (δ³⁴Smineral =-1.8 - 0.3‰) provide evidence for igneous derived sulfur. Blackwater’s host rocks, tectonic environment, metal signature and alteration match those of an intermediate-sulfidation epithermal system with both low- and intermediate sulfidation state sulfide minerals.
Atomic scale 0-pi transition in a high-Tc superconductor/ferromagnetic-insulator/high-T superconductor Josephson junction
Creators: name: Kawabata, Shiro
name: Tanaka, Yukio
name: Asano, Yasuhiro
Publisher: name: arXiv
Year: 2011
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the Josephson transport in a high-Tc superconductor/ferromagnetic-insulator(FI)/high-Tc superconductor numerically. We found the formation of a pi-junction in such systems. More remarkably the ground state of such junction alternates between 0- and pi-states when thickness of FI is increasing by a single atomic layer. We propose an experimental setup for observing the atomic-scale 0-pi transition. Such FI-based pi-junctions can be used to implement highly-coherent quantum bits.
description: 4 pages, 3 figures
Complete Genome Sequence of a Hepatitis E Virus Genotype 1e Strain from an Outbreak in Nigeria, 2017
Creators: name: Akanbi, Olusola Anuoluwapo
name: Harms, Dominik
name: Wang, Bo
name: Opaleye, Oluyinka Oladele
name: Adesina, Olufisayo
name: Osundare, Folakemi Abiodun
name: Ogunniyi, Abiodun
name: Naidoo, Dhamari
name: Devaux, Isabelle
name: Wondimagegnehu, Alemu
name: Peter, Clement
name: Ifeanyi, Okudo
name: Ogundiran, Opeayo
name: Ugochukwu, Uzoma
name: Mba, Nwando
name: Omilabu, Sunday A.
name: Ihekweazu, Chikwe
name: Bock, C. Thomas
Publisher: name: Robert Koch-Institut
Year: 2019
Subjects: subject: 610 Medizin und Gesundheit

description: Hepatitis E virus genotype 1 (HEV-1) is associated with large epidemics. Notably, HEV subtype 1e (HEV-1e) has caused HEV outbreaks in sub-Saharan Africa. We report here the second full-length genome sequence of an HEV-1e strain (NG/17-0503) from a recent outbreak in Nigeria in 2017. It shares 94.2% identity with an HEV-1e strain from Chad.
On limits of ab initio calculations of pairing gap in nuclei
Creators: name: Saperstein, E. E.
name: Baldo, M.
name: Lombardo, U.
name: Pankratov, S. S.
name: Zverev, M. V.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A brief review of recent microscopic calculations of nuclear pairing gap is given. A semi-microscopic model is suggested in which the ab-initio effective pairing interaction is supplemented with a small phenomenological addendum. It involves a parameter which is universal for all medium and heavy nuclei. Calculations for several isotopic and isotonic chains of semi-magic nuclei confirm the relevance of the model.
description: 16 pages, 6 figs
The role of cardiac-resident mesenchymal progenitors in the development of fibrosis in the heart
Creators: name: Paylor, Ben Arthur
Publisher: name: University of British Columbia
Year: 2016

description: Fibrosis is a response to injury that involves cell proliferation and deposition of extracellular matrix; pathological fibrosis can be considered to be imperfect wound healing that impairs organ function. Our understanding of the role and source of cardiac fibroblasts (CFs) in the development of pathological fibrosis is severely hampered by a lack of robust in vivo markers and understanding of the heterogeneity within this vaguely defined population. Here we demonstrate the existence of cardiac-resident mesenchymal progenitor cells (cMSCs, identified as CD31-:CD45-:PDGFRα+:Sca-1+) and show that their in vivo pharmacological modulation with the receptor tyrosine kinase inhibitors nilotinib or imatinib reduces fibrosis and improves cardiac function following acute or chronic cardiac injury. We observed in vivo the initial expansion of Sca-1+ cMSCs following acute cardiac injury contributes to mature collagen-producing PDGFRα+:Sca-1- CFs. In two models of acute injury, isoproterenol treatment and ligation of the left anterior descending artery (LAD), treatment with nilotinib led to reduced proliferation of both cMSCs and CFs but an increased relative prevalence of cMSCs, suggesting a blockade in the fibrogenic differentiation of these cells. Extending these observations into mdx mice, a model of chronic myocardial dystrophy displaying cardiac fibrosis after one year of age, we investigated the effects of long-term treatment with imatinib as a potential pharmacologic therapy. mdx mice treated with imatinib for 15 months displayed improved cardiac function and reduced cardiac fibrosis. These improvements were matched by a reduced quantity of cMSCs within treated myocardial tissue. Finally, given the well-known role of PDGFRα+ Sca-1+ mesenchymal progenitors in the development of fibrofatty infiltration in skeletal muscle, we postulated a role for phenotypically similar cMSCs in the fibrofatty infiltrate observed inarrhythmogenic cardiomyopathy. Using a genetic model that dysregulates quiescence in mesenchymal populations, we observed hyperproliferation of cMSCs and spontaneous generation of adipose deposits within the myocardium, supporting our hypothesis that cMSCs are the cellular source of the fibrofatty infiltrate. In their entirety, our findings demonstrate the importance of differing subsets of mesenchymal cell populations within the heart and potential therapeutic benefit of targeting them pharmacologically following acute ischemic damage or during chronic dystrophic injury.
Noise Performance Comparison of 1.5 um Correlated Photon Pair Generation in Different Fibers
Creators: name: Zhou, Qiang
name: Zhang, Wei
name: Cheng, Jie-rong
name: Huang, Yi-dong
name: Peng, Jiang-de
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, the noise performances of 1.5 um correlated photon pair generations based on spontaneous four wave-mixing in three types of fibers, i.e., dispersion shifted fiber, highly nonlinear fiber, and highly nonlinear microstructure fiber are investigated experimentally. Result of the comparison shows that highly nonlinear microstructure fiber has the lowest Raman noise photon generation rate among the three types of fibers while correlated photon pair generation rate is the same. Theoretical analysis shows that the noise performance is determined by the nonlinear index and Raman response of the material in fiber core. The Raman response raises with increasing doping level, however, the nonlinear index is almost unchanged with it. As a result, highly nonlinear microstructure fiber with pure silica core has the best noise performance and has great potential in practical sources of correlated photon pairs and heralded single photons.
description: 10 pages, 6 figures
A critical review of "The Origins of SARS-CoV-2: A Critical Review" by Holmes et al.
Creators: name: Nymton, Ema
Publisher: name: Zenodo
Year: 2021

description: A rebuttal of the Cell paper "A critical review of “The Origins of SARS-CoV-2: A Critical Review” by Holmes et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373617/) detailing the flaws of the document and hte clear bias and dishonesty of the authors.
Overexpression of IRONMAN1 in Arabidopsis results into longer roots under alkaline condition
Creators: name: Gautam, Chandan Kumar
Publisher: name: figshare
Year: 2022
Subjects: subject: Molecular Biology
subject: 60705 Plant Physiology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Physiology

description: IRONMAN (IMA) peptides play an important role in iron (Fe) uptake (Grillet et al., 2018, Hirayama et al., 2018), and tolerance to non-available Fe (navFe) or alkaline condition (Gautam et al., 2021) where Fe is poorly available. Overexpression of IMAs result into upregulation of Fe-uptake, and coumarin pathway (Grillet et al., 2018, Hirayama et al., 2018, Gautam et al., 2021). Both IMA1(At1g47400) and IMA2(At1g47395) overexpressing lines shows tolerance to alkalinity in terms of better Fe uptake, and higher chlorophyll content in their shoots (Gautam et al., 2021). However, the root phenotype of these lines under navFe have been not been reported previously. Considering the significance of roots in nutrients uptake and response to edaphic factors, it becomes important to study their roots. Meng et al., 2021 have recently reported the increase in root length of IMA1ox lines under Fe-deficient condition created by Ferrozine addition into the nutrient media with no external Fe source. However, the root phenotype under navFe, which reflects the near-natural Fe-deficiency condition have not been reported. Here, we report our observation that the IMA1 overexpression lines show longer root length under navFe condition as compared to wild type (Col-0) seedlings (Fig. 1). In summary, overexpression of IMA1 leads to longer root length under Fe-deficiency induced by either Ferrozine at physiological pH, or FeCl3 at circumneutral pH. Thus, apart from enhancement of Fe uptake pathway and release of Fe mobilizing coumarins, IMA1ox lines undergo change in the root system architecture to enhance Fe uptake under Fe deficiency.
The role of Fas-mediated apoptotic pathway in amyloid-induced beta-cell death
Creators: name: Park, Yoo Jin
Publisher: name: University of British Columbia
Year: 2015

description: In type 2 diabetes (T2D), progressive dysfunction and loss of beta-cells in pancreatic islets eventually leads to hyperglycemia. The formation of toxic protein aggregates known as islet amyloid contributes to beta-cell dysfunction and death in T2D. Islet amyloid is formed mainly by aggregation of the beta-cell hormone named islet amyloid polypeptide (IAPP), which is produced and released along with insulin. Amyloid also forms in cultured and transplanted human islets, indicating that in addition to its role in pathogenesis of T2D, amyloid formation contributes to islet graft failure in type 1 diabetes (T1D). The mechanism(s) underlying amyloid-induced beta-cell death are still unclear. Fas is a cell death receptor that has been implicated in the pathogenesis of both T1D and T2D. We hypothesised that amyloid-induced beta-cell death is mediated, at least partially, by activation of the Fas apoptotic pathway and that blocking the key steps in this pathway may protect beta-cells from amyloid toxicity in T2D and islet grafts in T1D. Our studies showed that endogenously formed human IAPP aggregates induce beta-cell Fas upregulation leading to interaction of Fas and its ligand FasL, thereby promoting activation of the Fas apoptotic pathway initiated by caspase-8. Blocking Fas/FasL interaction reduced amyloid-induced beta-cell apoptosis, and beta-cell specific deletion of Fas or caspase-8 in hIAPP-expressing mouse islets improved beta-cell survival and function. We further demonstrated that amyloid-induced beta-cell Fas upregulation is mediated by interleukin-1beta (IL-1beta). Amyloid formation in cultured islets closely correlated with elevated IL-1beta production and blocking IL-1beta signalling reduced amyloid-induced beta-cell Fas upregulation, caspase-8 activation and apoptosis. Moreover, IL-1beta-induced beta-cell dysfunction caused impaired prohIAPP processing and potentiated amyloid formation, which was restored by blocking IL-1 receptor. These findings support a dual role for IL-1beta in amyloid formation and its beta-cell toxicity. Similarly, enhancing islet function by the GLP-1 receptor agonist exenatide improved impaired prohIAPP processing and reduced amyloid formation. In summary, our data show that the Fas apoptotic pathway plays a major role in amyloid-induced beta-cell death and that blocking the key mediators of this pathway may provide a new therapeutic strategy to preserve beta-cells in T2D and prolong islet graft survival in T1D.