cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Development and evaluation of novel recombinant adenovirus-based vaccine candidates for infectious bronchitis virus and Mycoplasma gallisepticum in chickens
Creators: name: Zhang, Dongchao
name: Long, Yuqing
name: Li, Meng
name: Gong, Jianfang
name: Li, Xiaohui
name: Lin, Jing
name: Meng, Jiali
name: Gao, Keke
name: Zhao, Ruili
name: Jin, Tianming
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Avian infectious bronchitis caused by the infectious bronchitis virus (IBV), and mycoplasmosis caused by Mycoplasma gallisepticum (MG) are two major respiratory diseases in chickens that have resulted in severe economic losses in the poultry industry. We constructed a recombinant adenovirus that simultaneously expresses the S1 spike glycoprotein of IBV and the TM-1 protein of MG (pBH-S1-TM-1-EGFP). For comparison, we constructed two recombinant adenoviruses (pBH-S1-EGFP and pBH-TM-1-EGFP) that express either the S1 spike glycoprotein or the TM-1 protein alone. The protective efficacy of these three vaccine constructs against challenge with IBV and/or MG was evaluated in specific pathogen free chickens. Groups of seven-day-old specific pathogen free chicks were immunized twice, two weeks apart, via the oculonasal route with the pBH-S1-TM-1-EGFP, pBH-S1-EGFP, or pBH-TM-1-EGFP vaccine candidates or the commercial attenuated infectious bronchitis vaccine strain H52 and MG vaccine strain F-36 (positive controls), and challenged with virulent IBV or MG two weeks later. Interestingly, by days 7 and 14 after the booster immunization, pBH-S1-TM-1-EGFP-induced antibody titre was significantly higher (P < 0.01) compared to attenuated commercial IBV vaccine; however, there was no significant difference between the pBH-S1-TM-1-EGFP and attenuated commercial MG vaccine groups (P > 0.05). The clinical signs, the gross, and histopathological lesions scores of the adenovirus vaccine constructs were not significantly different from that of the attenuated commercial IBV or MG vaccines (positive controls) (P > 0.05). These results demonstrate the potential of the bivalent pBH-S1-TM-1-EGFP adenovirus construct as a combination vaccine against IB and mycoplasmosis.
Respiratory disease of small ruminants
Creators: name: MacKay, Evelyn
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: goat
sheep
pneumonia
respiratory disease

description: Although respiratory disease of small ruminants manifests and responds similarly to respiratory disease of cattle, there is much less research and resources aimed at diagnosis and treatment. Limited vaccinations, diagnostic tests and approved pharmaceuticals make it a more challenging landscape to navi­gate for the practitioner. Despite this, similar approaches in case workup, treatment selection and monitoring can be uti­lized as with other species. A few diseases unique to small ru­minants should be kept in mind, and proper drug usage should be in the forefront of practitioners’ minds when managing these cases.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Common emergency and musculoskeletal repairs in the small ruminant
Creators: name: Muir, Andrew
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: musculoskeletal
emergency
small ruminant
external coaptation

description: Small ruminants suffer musculoskeletal disease most com­monly due to fracture, wildlife attack, fence injuries, infec­tious or degenerative diseases. Due to their size, behavior and physiologic healing capacity compared to other species, they are excellent orthopedic patients. External coaptation is well tolerated in these species and can be applied in many cases, and often results in a satisfactory clinical outcome. In unfor­tunate circumstances where limb amputation is elected, small ruminants appear to tolerate this procedure and can have fair to good long-term outcomes.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Efficient Semiparametric Inference Under Two-Phase Sampling, With Applications to Genetic Association Studies
Creators: name: Tao, Ran
name: Zeng, Donglin
name: Lin, Dan-Yu
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: In modern epidemiological and clinical studies, the covariates of interest may involve genome sequencing, biomarker assay, or medical imaging and thus are prohibitively expensive to measure on a large number of subjects. A cost-effective solution is the two-phase design, under which the outcome and inexpensive covariates are observed for all subjects during the first phase and that information is used to select subjects for measurements of expensive covariates during the second phase. For example, subjects with extreme values of quantitative traits were selected for whole-exome sequencing in the National Heart, Lung, and Blood Institute (NHLBI) Exome Sequencing Project (ESP). Herein, we consider general two-phase designs, where the outcome can be continuous or discrete, and inexpensive covariates can be continuous and correlated with expensive covariates. We propose a semiparametric approach to regression analysis by approximating the conditional density functions of expensive covariates given inexpensive covariates with B-spline sieves. We devise a computationally efficient and numerically stable EM-algorithm to maximize the sieve likelihood. In addition, we establish the consistency, asymptotic normality, and asymptotic efficiency of the estimators. Furthermore, we demonstrate the superiority of the proposed methods over existing ones through extensive simulation studies. Finally, we present applications to the aforementioned NHLBI ESP. Supplementary materials for this article are available online
Setting up yearly preventive health plan for sheep, goats, camelids
Creators: name: Miller, Blake
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: sheep
goats
camelids
llama
alpaca

description: The objective of this presentation is to provide useful and ap­plicable information about preventative medicine that can be imparted in an oral or written form to clients that own small ruminants or camelids. Owners often have serious issues re­quiring immediate attention that could have been avoided if proper husbandry and maintenance was provided prior to the incident, further reinforcing the idea that preventative medi­cine is the best medicine.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Knowledge management strategic orientation in SMEs
Creators: name: Azyabi, Naief Gashoor S
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: The research involved the development of a theoretical framework relating KM strategic orientation, business strategy, information technology/information systems (IT/IS) and contextual factors. KM strategic orientation was investigated in terms of four sets of dimensions: knowledge sources, knowledge types, KM processes and knowledge-base (broad and deep knowledge-base). Based on an organisation’s orientation towards these dimensions, three KM strategies were proposed: aggressive KM strategy, conservative KM strategy and balanced KM strategy. It is argued that business strategy has a great influence on KM strategy; thus these three strategies were linked to business strategies based on the typology of Miles and Snow (1978): prospectors, defenders and analysers respectively. Besides the influence of business strategy, the contextual factors (organisation size, age and industry sector) are believed to be important in determining the KM strategic orientation of SMEs. It was proposed that the level of use and types of IT/IS depend on the KM strategic orientation of SMEs. Employing mixed methods (survey and interviews), this research found that Saudi SMEs tended to rely on both internal and external sources of knowledge without any significant difference in such reliance. A tacit-orientation approach was adopted significantly more than an explicit-orientation approach because the explicit-orientation approach required more financial, human and technological resources. In regard to the KM processes, the exploitation approach was adopted significantly more than the exploration approach. Moreover, SMEs prepared and preferred their employees to be multi-skilled and able to perform different tasks within the organisations. The research confirmed the influence of business strategy on KM strategic orientation because the proposed relationship between Miles and Snow typology and the proposed KM strategies was confirmed. Besides the business strategy, SME decisions towards KM strategic dimensions were highly influenced by the contextual factors such as organisation size, age, industry sector, resources limitation, the influence of customers/suppliers and the manager’s characteristics. This research found that SMEs were oriented towards the non-expensive and easy to use IT/IS applications. The IT/IS applications were classified, based on the findings of this research into: Internet-based IT/IS, IT/IS for collaboration and IT/IS for codification. There were correlations found between KM strategy and IT/IS applications (i.e. between the aggressive KM strategy and IT/IS for collaboration, and between the conservative KM strategy and IT/IS for codification), which confirmed the association between KM strategy and IT/IS applications.
A global corrected SRTM DEM product for vegetated areas
Creators: name: Zhao, Xiaoqian
name: Su, Yanjun
name: Hu, Tianyu
name: Chen, Linhai
name: Gao, Shang
name: Wang, Rui
name: Jin, Shichao
name: Guo, Qinghua
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health
subject: Plant Biology

description: It has been found that the Shuttle Radar Topography Mission (SRTM) digital elevation model (DEM) is systematically higher than the actual land surface in vegetated areas. This study developed a new globally corrected SRTM DEM through reducing its systematic bias in vegetated areas. Over 150, 000 km2 airborne light detection and ranging (LiDAR) data along with spaceborne LiDAR, global canopy height data, global canopy cover data and global land cover data were collected to correct the SRTM DEM. A linear regression based method was used to estimate the original SRTM DEM error and therefore correct the SRTM DEM data. The results show that the original SRTM DEM data is around 6 m higher than the actual land surfaces on average across all vegetation types. Our corrected SRTM DEM data can significantly reduce the significant bias to near zero, and can also reduce the root-mean-square error by 1 m.
Additional file 1: of Effectiveness and safety of bifidobacteria and berberine in people with hyperglycemia: study protocol for a randomized controlled trial
Creators: name: Ming, Jie
name: Xu, Shaoyong
name: Liu, Chun
name: Liu, Xiangyang
name: Jia, Aihua
name: Ji, Qiuhe
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents*. (DOCX 591Â kb)
Particle Dynamics and Quasi-Periodic Oscillations in the GUP-Modified Schwarzschild Spacetime: Constraint Using Micro-Quasars Data
Creators: name: Hoshimov, Husanboy
name: Yunusov, Odil
name: Atamurotov, Farruh
name: Jamil, Mubasher
name: Abdujabbarov, Ahmadjon
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this work, we have worked out dynamical aspects for the particles moving around the GUP-corrected-Schwarzschild (S-GUP) black hole. We have calculated the innermost stable circular orbit (ISCO) around black hole and explored its implications for different microquasars. Additionally, we have shown that the Kerr black hole mimics S-GUP black hole after some tuning of parameters. Finally, considering the S-GUP black hole as a microquasar source, we have studied quasi-periodic oscillation (QPO). Further utilizing the available observational data of few microquasars, we have obtained constrains on the GUP parameter $ε$ as well.
description: 19 pages, 9 figures, 1 tables. To appear in Astroparticle Physics
Optimizing Cladding Elasticity to Enhance Sensitivity in Silicon Photonic Ultrasound Sensors
Creators: name: Erdogan, R. Tufan
name: Filonenko, Georgy A.
name: Picken, Stephen J.
name: Steeneken, Peter G.
name: Westerveld, Wouter J.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Optics (physics.optics)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Ultrasound is widely used in medical imaging, and emerging photo-acoustic imaging is crucial for disease diagnosis. Currently, high-end photo-acoustic imaging systems rely on piezo-electric materials for detecting ultrasound waves, which come with sensitivity, noise, and bandwidth limitations. Advanced applications demand a large matrix of broadband, high-resolution, and scalable ultrasound sensors. Silicon photonic circuits have been introduced to meet these requirements by detecting ultrasound-induced deformation and stress in silicon waveguides. Although higher sensitivities could facilitate the exploration of new applications, the high stiffness of the waveguide materials constrains the intrinsic sensitivity of the silicon photonic circuits to ultrasound signals. Here, we explore the impact of the mechanical properties of a polymer cladding on the sensitivity of silicon photonic ultrasound sensors. Our model and experiments reveal that optimizing the polymer cladding's stiffness enhances the resonance wavelength sensitivity. Experimentally, we show a fourfold increase in the sensitivity compared to the sensors without a cladding polymer and, a twofold sensitivity increase compared to the sensors with a cladding polymer of saturated cross-linking density. Interestingly, comparing experiments with the optomechanical model suggests that the change in Young's Modulus alone cannot explain the sensitivity increase. In conclusion, polymer-coated silicon photonic ultrasound sensors exhibit potential for advanced photo-acoustic imaging applications. It offers the prospect of increasing the ultrasound detection sensitivity of silicon photonic ultrasound sensors while using CMOS-compatible processes. This paves the way to integrate the polymer-coated silicon photonic ultrasound sensors with electronics to utilize the sensors in advanced medical imaging applications.
Are goats really just small cows?
Creators: name: Mongini, Andrea
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: goat
production
medicine

description: It would be so easy to make the bovine the standard by which we judge all ruminants. Unfortunately, nothing in life is ever so sim­ple. Yes, goats and cows have hair, four legs, and are ruminants. After that, the changes begin. In this talk, we will discuss both similarities and differences between cows and goats, with a bit of sheep information thrown in for good measure. There are many ways bovine veterinarians can easily cross over to the small ru­minant world but a few words of caution will be helpful to stay out of trouble. The focus of this talk is production medicine based but we will include some pharmacologic differences, too.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Additional file 1: of Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression
Creators: name: Zhang, Qi
name: Oh, Dong-Ha
name: DiTusa, Sandra
name: RamanaRao, Mangu
name: Baisakh, Niranjan
name: Dassanayake, Maheshi
name: Smith, Aaron
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Figure S1. Reproducibility of MNase-seq and RNA-seq. C1, control replicate 1; C2, control replicate 2; P1, −Pi replicate 1, P2, −Pi replicate 2. (A) Clustered heatmap of mapped MNase-seq samples with Spearman correlation coefficient (ρ). The distances among sample pairs are determined as 1-ρ. (B) Clustered heatmap of mapped rmRNA-seq samples with Pearson correlation coefficient (r). The distances among sample pairs are determined as 1-r. (PDF 161 kb)
Belongingness: Malaysian nurses’ experiences in the clinical workplace
Creators: name: Mohamed, Zainah
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: The need to belong has been proposed to be the most basic need for human psychological wellbeing. Lack of belongingness has been associated with stress, anxiety, and lack of esteem. Understanding the nature of nurses’ interconnection with others and their perceptions of belongingness has been linked to social and psychological functioning in the workplace. The purpose of this mixed-methods study was to explore factors contributing to Malaysian nurses’ sense of belonging in the workplace. Registered nurses (n = 437) from two hospitals in Kuala Lumpur, Malaysia, completed a previously validated questionnaires translated into the Malay language. Questionnaires were analysed using a variety of statistical measures for the close-ended questions, and content analysis for two open-ended questions. Subsequent to answering the survey, ten nurses participated in individual interviews which were thematically analysed. Nurses enhanced their sense of belonging through acceptance, ‘fitting in’, respect, and group harmony. There were no specific demographic factors contributing to the perceptions. The four core themes that emerged from the interview were: what it means to belong; being heard; finding a way to fit in; and the influence of Malay culture. The findings confirmed the positive effects of sense of belonging on feeling motivated, confidence level, and job satisfaction. The results also provide evidence for an effect of positive workplace culture which included supportive colleagues, the nursing manager and the other health care team members in enhancing a sense of belonging among nurses. Aspects of belongingness in Malaysian nurses reflect those of nurses elsewhere. However, there are specific cultural influences at play. Given the likely influence of Malaysian culture, development of a measurement scale based on Eastern culture would help in enhancing understanding of workplace practices among these groups of nurses.
Additional file 2: of Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression
Creators: name: Zhang, Qi
name: Oh, Dong-Ha
name: DiTusa, Sandra
name: RamanaRao, Mangu
name: Baisakh, Niranjan
name: Dassanayake, Maheshi
name: Smith, Aaron
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Plant Biology
subject: Computational Biology

description: Figure S2. Nucleosome patterns across the transcription termination site and gene body of rice genes. Regions 1000 bp upstream and downstream of the transcription termination site (TTS or 3′ boundary of the element), and gene body (GB, from TSS (5′ boundary) to TTS (3′ boundary) of a gene) were used to plot MNase-seq density under control conditions (A and B) and control and –Pi (C and D). (A) MNase-seq density for all rice genes across the TTS under control conditions. (B) MNase-seq density for all rice genes across the GB under control conditions. (C) MNase-seq density of PCG across the TTS from 24-h control and –Pi rice shoots. (D) MNase-seq density of PCG across the GB from 24-h control and –Pi rice shoots. (PDF 77 kb)
Additional file 3: of Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression
Creators: name: Zhang, Qi
name: Oh, Dong-Ha
name: DiTusa, Sandra
name: RamanaRao, Mangu
name: Baisakh, Niranjan
name: Dassanayake, Maheshi
name: Smith, Aaron
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: Computational Biology

description: Figure S3. Correlations between nucleosome patterns and gene expression. (A) Heatmap of MNase-seq density of PCG sorted by their expression level under control conditions from RNA-seq analysis of the same tissue (1st highest, 5th lowest). The vertical line in the middle of the heatmap indicates the TSS. (B) Average plot of the same data with genes grouped by their expression levels. (PDF 65Â kb)
The invisible cigarette, the production of smoking culture and identity in Indonesia
Creators: name: Priyatna, Centurion Chandratama
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This thesis examines how smoking culture is represented in Indonesia and how cigarette advertisements create identities as an aspiration for contemporary Indonesians, especially the influential middle class. The thesis examines smoking culture in light of the dramatic cultural change occurring in what is the largest Muslim country in the world. It involved fieldwork in advertising agencies in Indonesia, which revealed the processes entailed in producing advertisements, a semiotic analysis of cigarette advertisements and an examination of the sociocultural factors that shape smoking behaviours and policy responses to tobacco use. It is argued that the nexus between smoking culture and Indonesian identity needs to be understood in light of globalization and the hybridisation of local traditional influences (local smoking culture, identity, class, and religion) and modern influences (contemporary industry, lifestyle, and global health).
Small ruminant dairy production for the bovine practitioner
Creators: name: Mongini, Andrea
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: goat
sheep
dairy

description: Goat and sheep dairies are a growing subset of the dairy indus­try in the United States. Although sheep and goats differ signifi­cantly from cattle in some ways, bovine practitioners have a wealth of expertise that can and does greatly benefit the small ruminant dairy industry. The need for greater utilization of knowledge exists and can have a large impact on profitability and sustainability of small ruminant dairies. In this talk, we will review the areas of goat and sheep dairies where bovine veterinarians can have the most influence and how the small ruminants differ from cows in a dairy setting.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Giving and receiving feedback
Creators: name: Stup, Richard E.
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: leadership
feedback
performance
motivation
labor
employee development

description: Feedback is a powerful tool that can strongly influence human relationships, behaviors and careers. Professionals who master giving feedback can become exceptional leaders and effective practitioners. This workshop is about learning to give feed­back to employees, peers and clients to motivate change and improvement. It is also about learning to accept feedback as a powerful means for personal growth.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Characterization of a novel protein translocation system found ubiquitously in the membranes of Gram-negative bacteria
Creators: name: Selkrig, Joel
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Bacteria have evolved complex protein machinery to secrete proteins into the environment. In Gram-negative bacteria, secreted substrates require efficient targeting and translocation across the inner- and outer-membrane by protein secretion systems. The Omp85 protein superfamily is evolutionarily conserved and functions by translocating substrates into, or across, the outer membrane of Gram-negative bacteria. This thesis describes the discovery of a novel protein secretion machine that is required for the efficient delivery of a group of surface exposed proteins called autotransporters. We have named this protein secretion system the translocation and assembly module (TAM) which is composed of the Omp85 outer membrane component TamA and the inner membrane protein TamB which together interact to form a complex spanning the periplasmic space. Chapter three describes the genomic relationship between tamA and tamB and a bioinformatic analysis of the protein subdomains. The protein products within the operon were then localized and their membrane topology determined. Chapter 4 presents the protein-protein interactions within the TAM complex. Finally, determination of the function of the TAM complex and the requirements for particular subdomains is presented in Chapter 5. Together, these findings have uncovered a novel protein secretion system within the membranes of Gram-negative bacteria. Further, this work has elucidated the function of this protein complex as a mediator of efficient secretion of autotransporters. Due to the virulence associate functions of autotransporter substrates, therapeutic inhibition of the TAM complex may prove to be a viable pursuit to inhibit Gram-negative bacterial infections.
The political economy of emergency safeguard measures in trade in services agreements
Creators: name: Mohamed Khalid, Nor Arlinda
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Although escape clauses and safeguard measures found in most international agreements are theoretically deemed as uncertainty management devices that help to facilitate cooperation among states, this thesis shows that whether or not a safeguard measure can do so depends on the degree of complexity of the negotiating environment. This thesis presents the case based on the prolonged negotiations on Emergency Safeguard Measures (ESM) in concluding the services trade agreement at the World Trade Organization (WTO) and compares that case with progress made on ESM negotiations in bilateral and regional trade agreements. As uncertainty management devices, ESMs can help to mitigate the adverse political consequences of liberalization that cannot be fully predicted due to the informational and cognitive uncertainties surrounding services liberalization. Empirical evidence is gathered from primary interviews with trade representatives to the WTO in Geneva, ASEAN Secretariat official, policymakers and national trade negotiators of the bilateral and regional trade agreements, as well as documentary sources. The findings show that the level of acceptance of ESM for services trade differs at different levels of negotiations because of the different degrees of complexity at multilateral, regional and bilateral negotiations, which compound the informational and cognitive uncertainty associated with both services liberalisation and the use of ESM. The high degree of uncertainty surrounding the ESM has contributed to deadlock in ESM negotiations at the WTO. At the WTO, because of the high degree of complexity given by the large number of countries involved in the negotiations, the diversity of negotiating countries, and the multi-faceted and technical nature of services trade negotiations, an escape clause such as ESM itself acts as a source of uncertainty for developed countries in particular who are thus unwilling to agree to including ESM for services trade at the WTO. However, at regional and bilateral negotiations, ESM can act as an uncertainty management device because of the reduced complexity and thus lower degree of uncertainty at these negotiations. At the same time, developed countries seem willing to forgo the uncertainty generated by the ESM due to the anticipated non-economic longer-term gains from these bilateral and regional trade agreements, provided the ESM clauses in these agreements are ambiguously worded such that they create flexibility for both/all parties to the agreement. Whether or not the flexible ESM in these agreements is ultimately workable, remains to be seen.
Additional file 5: of Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression
Creators: name: Zhang, Qi
name: Oh, Dong-Ha
name: DiTusa, Sandra
name: RamanaRao, Mangu
name: Baisakh, Niranjan
name: Dassanayake, Maheshi
name: Smith, Aaron
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Mental Health
subject: Plant Biology
subject: Computational Biology

description: Figure S4. Significantly enriched GO terms for clusters ABC (type I gene) and DEF (type II gene). The color of the node represents the corrected p-value with a color scale ranging from yellow (corrected p-value = 0.05) to dark orange (corrected p-value = 5 × 10−7). (PDF 443 kb)
Option pricing with a natural equivalent martingale measure for log-symmetric levy price processes
Creators: name: Tan, Ying Oon
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This thesis examines the pricing of options when the stock price follows a log-symmetric Levy process. Models in continuous time and discrete time are considered. We identify situations when there is an equivalent change of measure that preserves the Levy property, symmetry and the family of symmetric distributions of the returns (log-returns if discrete time), and makes the discounted price process into a martingale. We call such measures natural equivalent martingale measures. In continuous time, when a natural equivalent martingale measure exists it is unique. It can be obtained by changing only the location or the scale parameter of the symmetric distribution if the Brownian component in present or absent, respectively, in the Levy process. The analogous natural equivalent martingale measure in discrete time always exists but not unique. It can be obtained by changing the location and the scale parameters of the symmetric distribution. Option pricing with natural equivalent martingale measure is arbitrage-free. We apply this approach to obtain new and elegant option pricing formulae for log-symmetric variance gamma and log-symmetric normal inverse Gaussian models.
Vivencia Perezhivanie in the everyday life of children
Creators: name: Quinones, Gloria
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This thesis uses cultural – historical framework to research the everyday life of children in an urban and a rural community in Monterrey, Nuevo León, México. A wholeness approach was used to investigate preschool and family institutional practices and activities. The different practices and activities identified were play, mealtimes and homework and were analysed focusing on the emotional experiences children lived with others. The focus of this thesis was to examine children’s emotional, intense and dramatic experiences theorized in cultural-historical theory as perezhivanie in Russian and vivencia in Spanish. The literature review focused on analysing how emotions were researched. A common theme in these studies indicates researchers focused exclusively on the child when studying their emotions removing the child from the social and cultural context. Therefore, the research question in thesis focuses on the role that emotions play in the child’s social situation of development and in their everyday life experiences and how can emotions be researched to ascertain the significance of Mexican children’s learning and development. The review of the literature highlights the importance of researching emotions using innovative research methodologies. Much of the literature found argues that in order to investigate a complex topic such as emotions multiple approaches were needed. The focus of this thesis was to pay attention to multiple perspectives of children and the educators using visual methodologies. Visual methodologies allowed visually interpreting and discussing how children learned and made sense of their emotions in the social situations they occurred. A new methodological tool ‘Visual Vivencias’ is theorized and used to capture children’s moments of emotional intensity where they learn and develop across their participation in preschool and family institutions. Adding to cultural- historical scholarship models are proposed to study vivencia perezhivanie in everyday life of children and in play. These models argue that in order to study children’s emotions and affects, it needs to be studied in unity with intellect (cognition).This thesis discusses how children’s vivencias perezhivanie as their everyday emotional, intense and dramatic experiences needs to be recognized by educators as they enable children to learn and develop in their own cultural communities.
Brain structure and circuitry in body dysmorphic disorder (BDD) patients: a multimodal neuroimaging study
Creators: name: Buchanan, Benjamin
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Body dysmorphic disorder (BDD) is a mental disorder with five times the prevalence of anorexia, affecting up to 2.4% of the general population. The main symptom is a fixation on a feature of appearance that they attest looks ugly and they may engage in repetitive and ritualistic behaviour, including picking of their skin or checking their appearance in the mirror very frequently. The concern with appearance and associated behaviours are analogous to the obsessions and compulsions experienced in obsessive compulsive disorder (OCD). This thesis aimed to characterise the brain structure and circuitry of BDD to understand the mechanism that underlie the disorder's onset and maintenance. We acquired the largest BDD neuroimaging sample to date, scanning 20 BDD participants and compared them to 20 healthy controls. Three imaging techniques were reported; structural magnetic resonance imaging (MRI), diffusion tensor imaging (DTI) and resting state functional MRI. The structural data showed reduced volumes in the orbitofrontal and anterior cingulate cortex, while the DTI data revealed for the first time that BDD patients have compromised integrity of most major white matter tracts throughout the brain. Resting state functional MRI showed abnormalities in fronto-amygdala and occipital lobe connectivity. Collectively, our evidence contributed rich data showing widespread abnormalities in the brains of BDD participants. These abnormalities may be the foundation for BDD symptoms, including increased fearful threat perception, and dysfunction in self-reflection, executive function and visual processing. It was concluded that the frontal and fronto-amygdala deficits found in BDD are important to the disorder, and suggest it lies on a spectrum of anxiety disorders characterized by emotional dysregulation.
MARS: Multi-sample Allocation through Russian roulette and Splitting
Creators: name: Meyer, Joshua
name: Rath, Alexander
name: Yazici, Ömercan
name: Slusallek, Philipp
Publisher: name: arXiv
Year: 2024
Subjects: subject: Graphics (cs.GR)
subject: FOS: Computer and information sciences
subject: I.3.7

description: Multiple importance sampling (MIS) is an indispensable tool in rendering that constructs robust sampling strategies by combining the respective strengths of individual distributions. Its efficiency can be greatly improved by carefully selecting the number of samples drawn from each distribution, but automating this process remains a challenging problem. Existing works are mostly limited to mixture sampling, in which only a single sample is drawn in total, and the works that do investigate multi-sample MIS only optimize the sample counts at a per-pixel level, which cannot account for variations beyond the first bounce. Recent work on Russian roulette and splitting has demonstrated how fixed-point schemes can be used to spatially vary sample counts to optimize image efficiency but is limited to choosing the same number of samples across all sampling strategies. Our work proposes a highly flexible sample allocation strategy that bridges the gap between these areas of work. We show how to iteratively optimize the sample counts to maximize the efficiency of the rendered image using a lightweight data structure, which allows us to make local and individual decisions per technique. We demonstrate the benefits of our approach in two applications, path guiding and bidirectional path tracing, in both of which we achieve consistent and substantial speedups over the respective previous state-of-the-art.
description: 18 pages, 13 figures, to be published in SIGGRAPH Asia 2024 Conference Papers
Additional file 6: of Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression
Creators: name: Zhang, Qi
name: Oh, Dong-Ha
name: DiTusa, Sandra
name: RamanaRao, Mangu
name: Baisakh, Niranjan
name: Dassanayake, Maheshi
name: Smith, Aaron
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Figure S6. Changes of total phosphorus and inorganic phosphate concentrations in response to phosphate starvation. All values are the mean ± standard error of the mean; n = 3 biological replicates with 3 technical repeats each. DW, dry weight; FW, fresh weight. (A) Total phosphorus (P) concentrations for shoots of 5-week-old seedlings grown under full nutrient (Ctrl) and Pi-starvation (−Pi) conditions. (B) Total P concentrations for roots of 5-week-old seedlings grown under full nutrient (Ctrl) and Pi-starvation (−Pi) conditions. (C) Inorganic phosphate (Pi) concentrations for shoots of 5-week-old seedlings grown under full nutrient (Ctrl) and Pi-starvation (−Pi) conditions. (D) Pi concentrations for roots of 5-week-old seedlings grown under full nutrient (Ctrl) and Pi-starvation (−Pi) conditions. (PDF 38 kb)
Animal Identification and Traceability in the United States: Market Impacts and Implications
Creators: name: Shear, Hannah E.
name: Pendell, Dustin L.
name: Shear, Hannah E.
name: Pendell, Dustin L.
Publisher: name: Unknown
Year: 2020
Subjects: Food Consumption/Nutrition/Food Safety
International Relations/Trade
Livestock Production/Industries

description: Livestock traceability has increasingly become a focus for the USDA, the National Cattlemen’s Beef Association, high-volume beef-exporting states, and other beef industry stakeholders. The focus on traceability within the United States began after several international animal disease outbreaks and continues to be of importance with African Swine Flu spreading across Asia. Mitigating adverse future disease outbreaks, as well as maintaining export markets through a positive international perception of U.S. beef has become a top priority. Implementing a national disease traceability program would enable the industry to track and reduce the potential losses due to an outbreak. However, such a system comes at a large cost, mainly to cow-calf producers. This study utilizes an equilibrium displacement model (EDM) to determine the impacts of a beef cattle disease traceability system in the United States. Utilizing the EDM allows us to provide a comparison of how the various beef sectors would need to respond to offset the costs of a national disease traceability program.
Balancing the hat rack
Creators: name: Kohtz, Elizabeth
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: work-life balance
self-care
burnout
well-being
mental health

description: Veterinary medicine is a wonderful and rewarding profession. It can also be a challenging, demanding and stressful career. Practitioners need to be able to balance family, work, hobbies and other responsibilities without becoming overwhelmed. There are a plethora of podcasts, blogs, articles and books on well-being and work-life balance. Unfortunately, there is not an easy solution to balance life; what works for one person might not work for another. In this lecture, completing the stress cycle will be discussed, a method to measure overall well-being will be introduced, and the need to set priorities and tips and suggestions for work-life balance will be explored.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings
Additional file 7: of Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression
Creators: name: Zhang, Qi
name: Oh, Dong-Ha
name: DiTusa, Sandra
name: RamanaRao, Mangu
name: Baisakh, Niranjan
name: Dassanayake, Maheshi
name: Smith, Aaron
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Figure S5. Changes in nucleosome occupancy at the exons of rice genes in response to phosphate starvation. MNase-seq density of exons grouped according to their length: (A) 170–240 bp; (B) 315–350 bp; (C) 480–550 bp (D) 645–715 bp under control and −Pi conditions. Plots are centered at the 5′ boundaries of the exons. (PDF 58 kb)
Fourier transform infrared microspectroscopy for the characterisation of human embryonic and human induced pluripotent stem cells
Creators: name: Cao, Julie Oanh
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen clinically destined pluripotent and multipotent stem cells. In this work, we explored the utility of this technique to distinguish between several human embryonic and human induced pluripotent stem cell lines and their differentiated progeny, based on their macromolecular chemistry. We observed both intra-class and inter-class biochemical variation within the undifferentiated stem cell cohorts, in addition to spectroscopic differences between both classes during their differentiation towards mesendodermal and ectodermal lineages. Chemometric comparisons of the progeny cells alone, indicated that they were phenotypically distinct, suggesting that current reprogramming methods do not yield human induced pluripotent stem cells that are equivalent to human embryonic stem cells, in spite of immunohistochemistry results suggesting the antithesis. However, whether these phenotypical changes are indicative of the inadequacies of the reprogrammed cells to form therapeutically useful lineage committed progeny needs to be established. To elucidate the basis of the phenotypic differences observed between these pluripotent stem cells, we decided to investigate the role of environmental factors influencing these spectral 'signatures', by varying their growth environments. Accordingly, we employed Fourier transform infrared (FTIR) microspectroscopy to acquire spectra from several hESC lines and their derived cell types maintained in both feeder dependent and feeder independent conditions, in KOSR based or mTESR based hESC medium, and either mechanically or enzymatically dissociated. It was found that hESC lines grown under different conditions possessed unique FTIR spectroscopic ‘signatures’ and that these spectroscopic differences persisted even upon differentiation towards mesendodermal lineages. The results from this study illustrates the power of this modality for defining macromolecular phenotypic differences between several lines of human embryonic stem cells and human induced pluripotent stem cells and their lineage committed progeny. The technique has been shown to be highly sensitive, as indicated by its ability to detect biochemical differences even between stem cell lines of the same class. Further, the results indicate that the spectroscopic phenotypes are sensitive to a combination of genetics and environmental factors.
Profitability of rural practice
Creators: name: Sellers, Glen
Publisher: name: American Association of Bovine Practitioners  Conference Proceedings
Year: 2023
Subjects: profitability
rural mixed animal practice
income
EBITDA

description: There is a crisis in rural veterinary medicine as rural practitio­ners face challenges in different business environments. Rural veterinary practices are complex organizational systems with economic and demographic challenges directly associated with various causal conditions which affect practice profitability and efficiency. Supported by a grant from the U.S. Department of Agriculture, data was collected from 16 mixed rural veteri­nary practices in the southeastern United States over 4 years. A 3-year financial analysis found profits and owners’ compen­sation of 20.3% of gross revenues, cost of goods sold (COGS) of 37.8% of gross revenues, practice and doctor averages cli­ent transactions of $102 and $117, respectively. Population and income averages within 40 miles of the practice were 452,939 people with household incomes of $67,780. Compared to the averaged Well-Managed Practice Benchmarks 2019, American Animal Hospital Association 2019, and American Veterinary Medical Association 2017 data, potential causal conditions chal­lenges for rural practices limiting profitability are COGS, clini­cal revenue production, and clinical work efficiency.
description: American Association of Bovine Practitioners Conference Proceedings, No. 55 (2022): 2022 Annual Conference Proceedings