cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Lessons learned and recommendations for data coordination in collaborative research: The CSER consortium experience
Creators: name: Li, T.
name: Murali, P.
name: Chen, F.
name: Green, R.
name: Kvale, M.
name: Crosslin, D.R.
name: Muenzen, K.D.
name: Farnan, L.
name: Powell, B.C.
name: Amendola, L.M.
name: Kauffman, T.L.
name: Fullerton, S.M.
name: Lawlor, J.M.J.
name: Ou, J.
name: Robinson, J.O.
name: Hindorff, L.A.
name: Angelo, F.
name: Mittendorf, K.F.
name: Bensen, J.T.
name: Jarvik, G.P.
Publisher: name: Cell Press
Year: 2022

description: Integrating data across heterogeneous research environments is a key challenge in multi-site, collaborative research projects. While it is important to allow for natural variation in data collection protocols across research sites, it is also important to achieve interoperability between datasets in order to reap the full benefits of collaborative work. However, there are few standards to guide the data coordination process from project conception to completion. In this paper, we describe the experiences of the Clinical Sequence Evidence-Generating Research (CSER) consortium Data Coordinating Center (DCC), which coordinated harmonized survey and genomic sequencing data from seven clinical research sites from 2020 to 2022. Using input from multiple consortium working groups and from CSER leadership, we first identify 14 lessons learned from CSER in the categories of communication, harmonization, informatics, compliance, and analytics. We then distill these lessons learned into 11 recommendations for future research consortia in the areas of planning, communication, informatics, and analytics. We recommend that planning and budgeting for data coordination activities occur as early as possible during consortium conceptualization and development to minimize downstream complications. We also find that clear, reciprocal, and continuous communication between consortium stakeholders and the DCC is equally important to maintaining a secure and centralized informatics ecosystem for pooling data. Finally, we discuss the importance of actively interrogating current approaches to data governance, particularly for research studies that straddle the research-clinical divide.
Inter-layer Degree Correlations in Heterogeneously Growing Multiplex Networks
Creators: name: Fotouhi, Babak
name: Momeni, Naghmeh
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The multiplex network growth literature has been confined to homogeneous growth hitherto, where the number of links that each new incoming node establishes is the same across layers. This paper focuses on heterogeneous growth. We first analyze the case of two preferentially growing layers and find a closed-form expression for the inter-layer degree distribution, and demonstrate that non-trivial inter-layer degree correlations emerge in the steady state. Then we focus on the case of uniform growth. Surprisingly, inter-layer correlations arise in the random case, too. Also, we observe that the expression for the average layer-2 degree of nodes whose layer-1 degree is k, is identical for the uniform and preferential schemes. Throughout, theoretical predictions are corroborated using Monte Carlo simulations.
African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer
Creators: name: Kote-Jarai, Z.
name: The PRACTICAL Consortium
name: Dale, A.M.
name: Petrovics, G.
name: Truong, T.
name: Goodman, P.J.
name: Multigner, L.
name: Fowke, J.
name: Mills, I.G.
name: Karunamuni, R.A.
name: Brureau, L.
name: Cussenot, O.
name: Thompson, I.M., Jr.
name: Menegaux, F.
name: Crawford, D.C.
name: Leach, R.J.
name: Lin, H.-Y.
name: Cullen, J.C.
name: Romana, M.
name: Mohler, J.L.
name: Muir, K.
name: Andreassen, O.A.
name: Huynh-Le, M.-P.
name: UKGPCS Collaborators
name: Sanderson, M.
name: Tangen, C.M.
name: Cancel-Tassin, G.
name: Seibert, T.M.
name: Aldrich, M.
name: Park, J.Y.
name: Hu, J.J.
name: John, E.M.
name: Fontham, E.T.H.
name: Parent, M.-É.
name: Blot, W.J.
name: Taylor, J.A.
name: Drake, B.F.
name: Bush, W.S.
name: Blanchet, P.
name: Fan, C.C.
name: Bensen, J.T.
name: Kibel, A.S.
name: Zheng, W.
name: Lophatananon, A.
name: Srivastava, S.
name: Eeles, R.A.
name: Thompson, W.
Publisher: name: John Wiley and Sons Inc
Year: 2021

description: Polygenic hazard score (PHS) models are associated with age at diagnosis of prostate cancer. Our model developed in Europeans (PHS46) showed reduced performance in men with African genetic ancestry. We used a cross-validated search to identify single nucleotide polymorphisms (SNPs) that might improve performance in this population. Anonymized genotypic data were obtained from the PRACTICAL consortium for 6253 men with African genetic ancestry. Ten iterations of a 10-fold cross-validation search were conducted to select SNPs that would be included in the final PHS46+African model. The coefficients of PHS46+African were estimated in a Cox proportional hazards framework using age at diagnosis as the dependent variable and PHS46, and selected SNPs as predictors. The performance of PHS46 and PHS46+African was compared using the same cross-validated approach. Three SNPs (rs76229939, rs74421890 and rs5013678) were selected for inclusion in PHS46+African. All three SNPs are located on chromosome 8q24. PHS46+African showed substantial improvements in all performance metrics measured, including a 75% increase in the relative hazard of those in the upper 20% compared to the bottom 20% (2.47-4.34) and a 20% reduction in the relative hazard of those in the bottom 20% compared to the middle 40% (0.65-0.53). In conclusion, we identified three SNPs that substantially improved the association of PHS46 with age at diagnosis of prostate cancer in men with African genetic ancestry to levels comparable to Europeans.
Charge order induced in an orbital density-wave state
Creators: name: Singh, Dheeraj Kumar
name: Takimoto, Tetsuya
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Motivated by the recent ARPES measurements (Evtushinsky et. al., PRL {\bf 105}, 147201 (2010)) and evidence for the density-wave state for the charge and orbital ordering (García et al., PRL {\bf 109}, 107202 (2012)) in La$_{0.5}$Sr$_{1.5}$MnO$_4$, the issue of charge and orbital ordering in a two orbital tight-binding model for layered manganite near half doping is revisited. We find that the charge order with an ordering wavevector 2${\bf Q}$ = $(π, π)$ is induced by the orbital order of $B_{1g}$ representation with a different ordering wavevector ${\bf Q}$, where the primary order parameter results from the strong Fermi-surface nesting. The orbital and charge order parameters develop according to $\sqrt{T_{CO}-T}$ and $T_{CO}-T$, respectively, by decreasing the temperature below the orbital ordering temperature $T_{CO}$. Moreover, the orbital order is found to stabilize the CE-type spin arrangement observed experimentally below $T_{CE} < T_{CO}$.
Dal dialogo al conflitto
Creators: name: Vattimo, Gianni
Publisher: name: Trópos
Year: 2023

description: Congedo fino a un certo punto. Io progetto di stare ancora in contatto con gli studenti che lo vorranno attraverso seminari liberi e lavori di ricerca. Dunque forse non era necessario creare una specifica occasione come questa, e io ho avuto a lungo questo dubbio. Da ultimo, mi è sembrato che, come si dice, mi sarei fatto notare troppo di più con il non esserci che con l’esserci. Finiva per essere un atto di piccola arroganza, anche di fronte alla solennità con cui l’hanno affrontata i miei maggiori, penso soprattutto a Luigi Pareyson, maestro non solo di filosofia per me, che nella sua lezione di congedo aveva come inaugurato una ultima fase del suo pensiero niente affatto ripetitiva o epigonica. Perciò prego gli amici e colleghi, che mi fanno l’onore di essere qui, di considerare questa lezione come la semplice assoluzione di un dovere accademico che compio con un certo imbarazzo – visto che lo compio per la prima volta.
description: Trópos, V. 2 N. 1 (2009): Dialogo e conflitto
Generating nonclassical photon-states via longitudinal couplings between superconducting qubits and microwave fields
Creators: name: Zhao, Yan-Jun
name: Liu, Yu-Long
name: Liu, Yu-xi
name: Nori, Franco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Besides the conventional transverse couplings between superconducting qubits (SQs) and electromagnetic fields, there are additional longitudinal couplings when the inversion symmetry of the potential energies of the SQs is broken. We study nonclassical-state generation in a SQ which is driven by a classical field and coupled to a single-mode microwave field. We find that the classical field can induce transitions between two energy levels of the SQs, which either generate or annihilate, in a controllable way, different photon numbers of the cavity field. The effective Hamiltonians of these classical-field-assisted multiphoton processes of the single-mode cavity field are very similar to those for cold ions, confined to a coaxial RF-ion trap and driven by a classical field. We show that arbitrary superpositions of Fock states can be more efficiently generated using these controllable multiphoton transitions, in contrast to the single-photon resonant transition when there is only a SQ-field transverse coupling. The experimental feasibility for different SQs is also discussed.
description: 15 pages, 8 figures
Modeling Strangeness Enhancements to resolve the Muon Excess in Cosmic Ray Extensive Air Shower Data
Creators: name: Manshanden, Julien
name: Sigl, Günter
name: Garzelli, Maria V.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Experimental observations of extensive air showers have revealed an excess of the muon content with respect to their theoretical simulations, which we refer to as the muon puzzle. This muon puzzle hampers a precise determination of the ultra-high-energy cosmic ray mass composition. We investigate the potential of producing states of dense quark-gluon matter (which we call fireballs) to resolve the muon puzzle as quantified with data from the Pierre Auger Observatory on the depth of the shower maximum and the number of muons at ground. Adopting a phenomenological fireball model, we find that the inelasticity enhancement associated with the formation of a plasma state is in tension with data on the electromagnetic longitudinal shower development. Instead, we restrict the fireball model to only enhance the strangeness produced in Standard Model hadronic interactions, and dub this model the strangeball model. With an analytic approach based on the Heitler-Matthews model we then find explicit sets of strangeball parameters that resolve the muon puzzle. Constraints from data on shower-to-shower fluctuations of the muon number require strangeness enhancements already at energies accessible to current-generation collider experiments. At Tevatron and LHC energies we estimate 40% of the interactions to produce strangeballs, corresponding to a 5-9% increase of the average fraction of energy retained in the hadronic cascade compared to predictions from current hadronic interaction models. A comparison with relevant measurements of the LHCf and LHCb detectors does not directly exclude this scenario, though the obtained tension with LHCb suggests a stringent test at 14 TeV.
description: This is the Accepted Manuscript version of an article accepted for publication in Journal of Cosmology and Astroparticle Physics. Neither SISSA Medialab Srl nor IOP Publishing Ltd is responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at DOI 10.1088/1475-7516/2023/02/017. 29 pages, 13 figures, 3 tables
L’ermeneutica come ricostruzione della razionalità
Creators: name: Martinengo, Alberto
Publisher: name: Trópos
Year: 2023

description: Tra i numerosi equivoci più o meno rilevanti che sono sorti attorno al pensiero debole, il meno trascurabile è senza dubbio quello che attribuisce all’ermeneutica di Gianni Vattimo la scelta di abbandonare in toto il lessico della razionalità, per sostituirlo con un’imprecisata opzione irrazionalistica. Dalla tesi nietzscheana secondo cui tutto è interpretazione, molti hanno derivato l’idea che per l’ermeneutica “debolista” non vi sarebbero né verità né argomentazione, ma soltanto il flusso indefinito dei discorsi culturalmente situati. Questa lettura contestualista del pensiero di Vattimo ha avuto buon gioco a diffondersi e a riscuotere un discreto successo, anche grazie al forte impulso che negli ultimi decenni del ’900 hanno registrato gli studi sul multiculturalismo e sull’antropologia culturale, in Europa e in Italia. Più o meno esplicitamente, il pensiero debole è stato dunque interpretato come un vasto terreno comune, tanto ampio quanto indeterminato, in grado di tenere assieme diversi approcci e sensibilità teoriche, senza porre in alcun modo l’esigenza di una sintesi.
description: Trópos, V. 1 N. Speciale (2008): L'apertura del presente. Sull'ontologia ermeneutica di Gianni Vattimo
Hamiltonian cycles of balanced hypercube with more faulty edges
Creators: name: Lan, Ting
name: Lü, Huazhong
Publisher: name: arXiv
Year: 2022
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 68R10

description: The balanced hypercube $BH_{n}$, a variant of the hypercube, is a novel interconnection network for massive parallel systems. It is known that the balanced hypercube remains Hamiltonian after deleting at most $4n-5$ faulty edges if each vertex is incident with at least two edges in the resulting graph for all $n\geq2$. In this paper, we show that there exists a fault-free Hamiltonian cycle in $BH_{n}$ for $n\ge 2$ with $\left | F \right |\le 5n-7$ if the degree of every vertex in $BH_{n}-F$ is at least two and there exists no $f_{4}$-cycles in $BH_{n}-F$, which improves some known results.
Constraining the Extra Polarization Modes of Gravitational Waves with Double White Dwarfs
Creators: name: Xie, Ning
name: Zhang, Jian-dong
name: Huang, Shun-Jia
name: Hu, Yi-Ming
name: Mei, Jianwei
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The detection of gravitational wave (GW) has opened a new window to test the theory of gravity in the strong field regime. In general relativity (GR), GW can only possess two tensor polarization modes, which are known as the $+$ and $\times$ modes. However, vector and scalar modes can exist in some modified theories of gravity, and we can test the gravitational theories by probing these extra polarization modes. As a space-borne GW detector, TianQin will be launched in the 2030s, and it is expected to observe plenty of GW signals, including those from nearly ten-thousands double white dwarfs (DWDs) in our galaxy. This offers an excellent chance for testing the existence of extra polarization modes. In this article, we analyze the capability of detecting the extra polarization modes with DWDs. For the extra modes, we consider both the leading order dipole radiation and the subleading quadrupole radiation. We find that the capability of TianQin has very strong dependency on the source orientation. We also analyze all the verification binaries with determined position and frequency, and find that ZTF J1539 can give the best constraint on the extra polarization modes. We have also considered the case of TianQin twin constellation, and the joint observation with LISA.
description: 13 pages, 18 figures, 5 tables, matches the published version
title: Μοντελοποίηση και βελτιστοποίηση χρηματοοικονομικών ροών εταιρείας

Creators: name: Κωστακη Αννα-Μαρια
Publisher: name: Technical University of Crete
Year: 2022

description: Στην παρούσα εργασία θα απεικονιστούν αναλυτικά τα βήματα οικονομικής μοντελοποίησης μιας εταιρείας. Το όνομα της εταιρείας είναι Manufacturing SA η οποία δραστηριοποιείται στο χώρο της κατασκευής δεξαμενών αποθήκευσης πετρελαίου και του φυσικού αερίου.
Η οικονομική μοντελοποίηση είναι χρήσιμη για κάθε εταιρεία. Στην παρούσα εργασία η οικονομική μοντελοποίηση θα περιλαμβάνει την απεικόνιση των ιστορικών οικονομικών στοιχείων 3 προηγούμενων ετών με σκοπό βέβαια να γίνει και πρόβλεψη για τα 5 επόμενα έτη. Αυτό θα δώσει στην εταιρεία την ευελιξία πολυπαραγοντικά/πολυκριτηριακά να παρατηρεί όλη την εικόνα της ώστε να κατανοήσει την παρούσα κατάστασης της καθώς και να λαμβάνει τις βέλτιστες μελλοντικές αποφάσεις. Η οικονομική μοντελοποίηση δίνει την ικανότητα στις εταιρείες δύσκολα και πολύπλοκα προβλήματα να φαίνονται απλά.
Ο σκοπός της συγκεκριμένης μοντελοποίησης αφορά τον στρατηγικό σχεδιασμό που θα ακολουθήσει η εταιρεία για τα επόμενα 5 χρόνια. Η εταιρεία έχει να αποφασίσει ανάμεσα σε 3 σενάρια (plans)  προσφορών συνεργασίας. H διαφοροποίηση τους αφορά τις διαφορετικές τιμές που αφορούν κάποιες μεταβλητές πάνω στις οποίες θα βασιστεί και όλη μοντελοποίηση. Ο δείκτης που έχει θέσει ως προτεραιότητα αφορά τα Καθαρά Έσοδα προς διάθεση (Net Income to Common) και συγκεκριμένα επιθυμεί μεσοσταθμικά αυτός ο δείκτης για τα επόμενα 5 έτη να είναι ο βέλτιστος.
Θα επισυναφθούν 2 αρχεία Excel. Το ένα θα έχει το όνομα basic modeling Manufacturing Sa και το άλλο Strategy planning Manufacturing SA. Στο πρώτο απεικονιστεί όλη η μοντελοποίηση της επιχείρησης αναλύοντας 3 σενάρια το negative, basic, positive και θα χρησιμοποιηθεί για την παρουσίαση όλης της διαδικασίας της μοντελοποίησης. Ενώ στο δεύτερο  θα παρουσιαστεί μόνο στο τελευταίο κεφάλαιο της εργασίας στα αποτελέσματα-συμπεράσματα καθώς εκεί θα εξεταστούν τα 3 διαφορετικά σενάρια (plans) για τα οποία η εταιρεία καλείται να λάβει την βέλτιστη πολυπαραγοντικά/πολυκριτηριακά απόφαση.
An Incentive-Compatible Mechanism for Decentralized Storage Network
Creators: name: Vakilinia, Iman
name: Wang, Weihong
name: Xin, Jiajun
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: The dominance of a few big companies in the storage market arising various concerns including single point of failure, privacy violation, and oligopoly. To eliminate the dependency on such a centralized storage architecture, several Decentralized Storage Network (DSN) schemes such as Filecoin, Sia, and Storj have been introduced. DSNs leverage blockchain technology to create a storage platform such that the micro storage providers can also participate in the storage market. To verify the accurate data storage by the storage providers during a storage contract, DSNs apply a Proof of Storage (PoS) scheme to continuously inspect the storage service. However, continuous verification of the storage provider imposes an extra cost to the network and therefore end-users. Moreover, DSN's PoS verification is vulnerable to a service denying attack in which the storage provider submits valid PoS to the network while denying the service to the client. Considering the benefits and existing challenges of DSNs, this paper introduces a novel incentive-compatible DSN scheme. In this scheme, the PoS is conducted only if the client submits a challenge request. We model the storage service as a repeated dynamic game and set the players' payoffs such that the storage provider's dominant strategy is to honestly follow the storage contract. Our proposed mechanism leverages the smart-contract and oracle network to govern the storage agreement between the client and storage provider efficiently. Furthermore, our scheme is independent of a specific blockchain platform but can be plugged into any blockchain platform with smart-contract execution capability. As a proof of concept, we have implemented our scheme using solidity language and chainlink oracle network. The performance analysis demonstrates the applicability of our scheme.
Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry
Creators: name: Ruiz-Narváez, E.A.
name: Ambs, S.
name: Easton, D.F.
name: Yao, S.
name: Press, M.F.
name: Du, Z.
name: Nathanson, K.L.
name: Haddad, S.A.
name: Ahearn, T.
name: Haiman, C.A.
name: Lunetta, K.L.
name: Zirpoli, G.
name: Weinberg, C.R.
name: Dennis, J.
name: Deming, S.L.
name: Garcia-Closas, M.
name: Wiafe-Addai, B.
name: Gao, G.
name: Adedokun, B.
name: Taylor, J.A.
name: Ingles, S.A.
name: Michailidou, K.
name: Hu, J.J.
name: Blot, W.
name: John, E.M.
name: Bernstein, L.
name: Bandera, E.V.
name: Ogundiran, T.O.
name: Yarney, J.
name: Conti, D.V.
name: Rodriguez-Gil, J.L.
name: Olshan, A.F.
name: Olopade, O.I.
name: Bolla, M.K.
name: Kitahara, C.M.
name: Wang, Q.
name: Mancuso, N.
name: Palchoudhury, P.
name: Figueroa, J.
name: Ziegler, R.G.
name: Pharoah, P.D.P.
name: Nyante, S.
name: Chanock, S.J.
name: Nemesure, B.
name: Zheng, W.
name: Sucheston-Campbell, L.E.
name: Hennis, A.
name: Huo, D.
name: Awuah, B.
name: Dunning, A.M.
name: Palmer, J.R.
name: Ambrosone, C.B.
name: Ojengbe, O.
name: Sandler, D.P.
name: Bensen, J.T.
name: Troester, M.A.
Publisher: name: Oxford University Press
Year: 2021

description: Background: Polygenic risk scores (PRSs) have been demonstrated to identify women of European, Asian, and Latino ancestry at elevated risk of developing breast cancer (BC). We evaluated the performance of existing PRSs trained in European ancestry populations among women of African ancestry. Methods: We assembled genotype data for women of African ancestry, including 9241 case subjects and 10 193 control subjects. We evaluated associations of 179- and 313-variant PRSs with overall and subtype-specific BC risk. PRS discriminatory accuracy was assessed using area under the receiver operating characteristic curve. We also evaluated a recalibrated PRS, replacing the index variant with variants in each region that better captured risk in women of African ancestry and estimated lifetime absolute risk of BC in African Americans by PRS category. Results: For overall BC, the odds ratio per SD of the 313-variant PRS (PRS313) was 1.27 (95% confidence interval [CI] = 1.23 to 1.31), with an area under the receiver operating characteristic curve of 0.571 (95% CI = 0.562 to 0.579). Compared with women with average risk (40th-60th PRS percentile), women in the top decile of PRS313 had a 1.54-fold increased risk (95% CI = 1.38-fold to 1.72-fold). By age 85 years, the absolute risk of overall BC was 19.6% for African American women in the top 1% of PRS313 and 6.7% for those in the lowest 1%. The recalibrated PRS did not improve BC risk prediction. Conclusion: The PRSs stratify BC risk in women of African ancestry, with attenuated performance compared with that reported in European, Asian, and Latina populations. Future work is needed to improve BC risk stratification for women of African ancestry.
Analysis of the Correlation Dimension for Inertial Particles
Creators: name: Gustavsson, Kristian
name: Mehlig, Bernhard
name: Wilkinson, Michael
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We obtain an implicit equation for the correlation dimension which describes clustering of inertial particles in a complex flow onto a fractal measure. Our general equation involves a propagator of a nonlinear stochastic process in which the velocity gradient of the fluid appears as additive noise. When the long-time limit of the propagator is considered our equation reduces to an existing large-deviation formalism, from which it is difficult to extract concrete results. In the short-time limit, however, our equation reduces to a solvability condition on a partial differential equation. We show how this approach leads to a perturbative expansion of the correlation dimension, for which the coefficients can be obtained exactly and in principle to any order. We derive the perturbation series for the correlation dimension of inertial particles suspended in three-dimensional spatially smooth random flows with white-noise time correlations, obtaining the first 33 non-zero coefficients exactly.
description: 22 pages, 3 figures
Additional file 1 of The effect of CGRP and SP and the cell signaling dialogue between sensory neurons and endothelial cells
Creators: name: Leroux, Alice
name: Roque, Micaela
name: Casas, Elina
name: Leng, Jacques
name: Guibert, Christelle
name: L’Azou, Beatrice
name: Oliveira, Hugo
name: Amédée, Joëlle
name: Paiva dos Santos, Bruno
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: Computational Biology

description: Supplementary Material 1
Additional file 1 of SYK promotes the formation of neutrophil extracellular traps by inducing PKM2 nuclear translocation and promoting STAT3 phosphorylation to exacerbate hepatic ischemia-reperfusion injury and tumor recurrence
Creators: name: Chen, Xuejiao
name: Jiang, Chuanwei
name: Chen, Minhao
name: Li, Xiangdong
name: Yu, Wenjie
name: Qiu, Aigang
name: Sun, Linfeng
name: Pu, Liyong
name: Shi, Yuhua
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1
Oscillating bound states in non-Markovian photonic lattices
Creators: name: Lim, Kian Hwee
name: Mok, Wai-Keong
name: Kwek, Leong-Chuan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is known that the superposition of two bound states in the continuum (BIC) leads to the phenomenon of an oscillating bound state, where excitations mediated by the continuum modes oscillate persistently. We perform exact calculations for the oscillating BICs in a 1D photonic lattice coupled to a "giant atom" at multiple points. Our work is significantly distinct from previous proposals of oscillating BICs in continuous waveguide systems due to the presence of a finite energy band contributing band-edge effects. In particular, we show that the bound states outside the energy band are detrimental to the oscillating BIC phenomenon, and can be suppressed by increasing either the number of coupling points or the separation between each coupling point. Crucially, non-Markovianity is necessary for the existence of oscillating BIC, and the oscillation amplitude increases with the characteristic delay time of the giant atom interactions. We also propose a novel initialization scheme in the BIC subspace. Our work be experimentally implemented on current photonic waveguide array platforms and opens up new prospects in utilizing reservoir engineering for the storage of quantum information in photonic lattices.
description: 20 pages, 8 figures
Genetic variants in anti-Müllerian hormone-related genes and breast cancer risk: results from the AMBER consortium
Creators: name: Young, K.
name: Hong, C.-C.
name: Yao, S.
name: Haiman, C.A.
name: Lunetta, K.L.
name: Nichols, H.B.
name: Graff, M.
name: Palmer, J.R.
name: Olshan, A.F.
name: Troester, M.A.
name: Williams, L.A.
name: Ambrosone, C.B.
name: Ruiz-Narváez, E.A.
name: O’Brien, K.M.
name: Bensen, J.T.
Publisher: name: Springer
Year: 2021

description: Purpose: Circulating anti-Müllerian hormone (AMH) levels are positively associated with time to menopause and breast cancer risk. We examined breast cancer associations with single nucleotide polymorphisms (SNPs) in the AMH gene or its receptor genes, ACVR1 and AMHR2, among African American women. Methods: In the AMBER consortium, we tested 65 candidate SNPs, and 1130 total variants, in or near AMH, ACVR1, and AMHR2 and breast cancer risk. Overall, 3649 cases and 4230 controls contributed to analyses. Odds ratios (OR) and 95% confidence intervals (CI) for breast cancer were calculated using multivariable logistic regression. Results: After correction for multiple comparisons (false-discovery rate of 5%), there were no statistically significant associations with breast cancer risk. Without correction for multiple testing, four candidate SNPs in ACVR1 and one near AMH were associated with breast cancer risk. In ACVR1, rs13395576[C] was associated with lower breast cancer risk overall (OR 0.84; 95% CI 0.72, 0.97) and for ER+ disease (OR 0.75; CI 0.62, 0.89) (p < 0.05). Rs1220110[A] and rs1220134[T] each had ORs of 0.89–0.90 for postmenopausal and ER+ breast cancer (p ≤ 0.03). Conversely, rs1682130[T] was associated with higher risk of ER+ breast cancer (OR 1.17; 95% CI 1.04, 1.32). Near AMH, rs6510652[T] had ORs of 0.85–0.90 for breast cancer overall and after menopause (p ≤ 0.02). Conclusions: The present results, from a large study of African American women, provide limited support for an association between AMH-related polymorphisms and breast cancer risk and require replication in other studies.
La fede nella continuità
Creators: name: Bagetto, Luca
Publisher: name: Trópos
Year: 2023

description: Negli ultimi anni, la lontananza dell’ontologia dell’indebolimento da ogni progetto di ritorno alle cose stesse è stata duramente censurata. Anche per chi non era molto interessato a Husserl, l’ermeneutica del declino segnava il prevalere della cultura sulla natura, e di una filosofia delle parole sulla filosofia delle cose e del loro funzionamento. Perché – si diceva – il manifesto dell’ermeneutica del declino avrebbe potuto essere riassunto in uno slogan an- tagonistico a Husserl: “via dalle cose stesse”. Esso definisce una filosofia che non vuole essere scientifica, ma congetturale. Un viaggio che non mira all’evidenza della conoscenza, ma prende le mosse da una effettiva e insuperabile vaghezza dei contorni delle cose. Il pensiero debole si ripara dalla luce eccessiva e non si sente sedotto dall’appello alla visione chiara e distinta.
description: Trópos, V. 1 N. Speciale (2008): L'apertura del presente. Sull'ontologia ermeneutica di Gianni Vattimo
Domain formation in magnetic polymer composites: an approach via stochastic homogenization
Creators: name: Alicandro, R.
name: Cicalese, M.
name: Ruf, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 49J45, 49J55, 49S05, 82B20, 82B24 (Primary), 49Q20 (Secondary)

description: We study the magnetic energy of magnetic polymer composite materials as the average distance between magnetic particles vanishes. We model the position of these particles in the polymeric matrix as a stochastic lattice scaled by a small parameter $\varepsilon$ and the magnets as classical $\pm 1$ spin variables interacting via an Ising type energy. Under surface scaling of the energy we prove, in terms of $Γ$-convergence that, up to subsequences, the (continuum) $Γ$-limit of these energies is finite on the set of Caccioppoli partitions representing the magnetic Weiss domains where it has a local integral structure. Assuming stationarity of the stochastic lattice, we can make use of ergodic theory to further show that the $Γ$-limit exists and that the integrand is given by an asymptotic homogenization formula which becomes deterministic if the lattice is ergodic.
description: 31 pages
Non-BCS thermodynamic properties of H2S superconductor
Creators: name: Durajski, Artur P.
name: Szczesniak, Radoslaw
name: Li, Yinwei
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The present paper determines the thermodynamic properties of the superconducting state in the ${\rm H_{2}S}$ compound. The values of the pressure from $130$ GPa to $180$ GPa were taken into consideration. The calculations were performed in the framework of the Eliashberg formalism. In the first step, the experimental course of the dependence of the critical temperature on the pressure was reproduced: $T_{C}\in\left<31,88\right>$ K, whereas the Coulomb pseudopotential equal to $0.15$ was adopted. Next, the following quantities were calculated: the order parameter at the temperature of zero Kelvin ($Δ\left(0\right)$), the specific heat jump at the critical temperature ($ΔC\left(T_{C}\right)\equiv C^{S}\left(T_{C}\right)-C^{N}\left(T_{C}\right)$), and the thermodynamic critical field ($H_{C}\left(0\right)$). It was found that the values of the dimensionless ratios: $R_Δ\equiv 2Δ(0)/k_{B}T_{C}$, $R_{C}\equiv{ΔC\left(T_{C}\right)}/{C^{N}\left(T_{C}\right)}$, and $R_{H}\equiv{T_{C}C^{N}\left(T_{C}\right)}/{H_{C}^{2}\left(0\right)}$ deviate from the predictions of the BCS theory: $R_Δ\in\left<3.64,4.16\right>$, $R_{C}\in\left<1.59,2.24\right>$, and $R_{H}\in\left<0.144, 0.163\right>$. Generalizing the results on the whole family of the ${\rm H_{n}S}$-type compounds, it was shown that the maximum value of the critical temperature can be equal to $\sim 290$ K, while $R_Δ$, $R_{C}$ and $R_{H}$ adopt the following values: $6.53$, $3.99$, and $0.093$, respectively.
description: 7 pages, 6 figures
Ermeneutica del declino
Creators: name: Palmero, Piero
Publisher: name: Trópos
Year: 2023

description: L’ontologia del declino1 è la realizzazione di un pensiero ispirato da Nietzsche, Heidegger e Gadamer che assume, in Vattimo, un sapore originale. È quel sapore particolare che ci spingeva, alla fine degli anni settanta, a seguire i corsi di Estetica – e i relativi seminari – con grande interesse. La motivazione della scelta, per molti di noi, non era solo di ordine culturale (anche se in quell’ambiente si riusciva, finalmente, a percepire l’esistenza viva della filosofia contemporanea, francese, tedesca e americana). Sentivamo, oltre a ciò, che “ne andava di noi” e che i corsi e i seminari del dipartimento di ermeneutica non erano solo commenti a testi filosofici ma autentiche aperture di orizzonti, utili per capire la complessità disorientante di quegli anni.
description: Trópos, V. 1 N. Speciale (2008): L'apertura del presente. Sull'ontologia ermeneutica di Gianni Vattimo
Interpretazione e liberazione
Creators: name: Tomatis, Francesco
Publisher: name: Trópos
Year: 2023

description: Penso che per comprendere l’originalità della filosofia di Gianni Vattimo, caratterizzante tutto il suo cammino di pensiero nei differenti luoghi che abbia frequentato, occorra volgersi ad ascoltare e approfondire la correlazione, che essa mostra incessantemente, fra interpretazione e liberazione. Esaminare uno solo dei termini nel suo pensiero, condurrebbe indubbiamente a collocarlo fra i massimi esponenti del pensiero ermeneutico per un verso, per l’altro fra i filosofi che più abbiano criticato le strutture violente della razionalità e civiltà non solo occidentale, ricercando una dimensione ulteriore, capace di dar esistenza e voce alle differenti realtà umane nelle loro seppur minime peculiarità. Comprendere invece la reciproca interdipendenza, la circolarità fra interpretazione e liberazione propria al filosofare di Vattimo, oltre a coglierne il tratto forse distintivo implica anche accedere ad una visione sulle questioni attuali e avvenire dell’uomo di grande respiro, unicità intellettuale, capacità di ascolto di molteplici interrogativi, esigenze, prospettive.
description: Trópos, V. 1 N. Speciale (2008): L'apertura del presente. Sull'ontologia ermeneutica di Gianni Vattimo
Quantum field theory with ghost pairs
Creators: name: Liu, Jiangfan
name: Modesto, Leonardo
name: Calcagni, Gianluca
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We explicitly show that general local higher-derivative theories with only complex conjugate ghosts and normal real particles are unitary at any perturbative order in the loop expansion. The proof presented here relies on integrating the loop energies on complex paths resulting from the deformation of the purely imaginary paths, when the external energies are continued from imaginary to real values. Contrary to the case of nonlocal theories, where the same integration path was first proposed, for the classes of theories studied here the same procedure is not analytic, but the resulting theory is unitary and unique when the complex ghosts are present in pairs. As an explicit application, a special class of higher-derivative super-renormalizable or finite gravitational and gauge theories turns out to be unitary at any perturbative order if we exclude the complex ghosts from the spectrum of the theory, as it is normally accepted for Becchi-Rouet-Stora-Tyutin (BRST) ghosts. Finally, we propose an analogy between confined gluons in quantum Yang-Mills theory and classical complex pairs in local higher-derivative theories. According to such interpretation, complex ghosts will not appear on shell as asymptotic states because confined in what is natural to name "ghostballs."
description: 44 pages, 3 figures; v2: title changed, section 5 on gauge theories and gravity considerably expanded with diagrammatic proof of unitarity
SnowApp climate service for winter tourism centres
Creators: name: Mettiäinen, Ilona
name: Coath, Martin
name: Grist, Hannah
name: Harvey, Will
Publisher: name: Zenodo
Year: 2020
Subjects: climate service
winter tourism
sustainable tourism
climate adaptation

description: Leaflet on the climate service for winter tourism industry, co-designed by Blue-Action: Arctic Impact on Weather and Climate (EU Horizon 2020) WP5 CS1. English language version.
Loop quantum cosmology in 2+1 dimension
Creators: name: Zhang, Xiangdong
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: As a first step to generalize the structure of loop quantum cosmology to the theories with the spacetime dimension other than four, the isotropic model of loop quantum cosmology in 2+1 dimension is studied in this paper. We find that the classical big bang singularity is again replaced by a quantum bounce in the model. The similarities and differences between the 2+1 dimensional model and the 3+1 dimensional one are also discussed.
description: 13 pages, typos fixed
A proposito del rapporto tra elettrificazione e soviet
Creators: name: Salizzoni, Roberto
Publisher: name: Trópos
Year: 2023

description: In uno dei suoi ultimi libri, Ecce Comu. Come si ridiventa ciò che si era, Vattimo propone di riprendere e rilanciare del comunismo «l’aspetto ideale... quello che aspirava a una società libera dai rapporti di dominio e perciò dalle strutture proprietarie», ciò che sarebbe possibile soltanto «accompagnando l’ideale comunista con il rifiuto dell’economicismo, per giunta con pretese scientifiche, che l’ha affiancato nella sua formulazione marxista-sovietica. Secondo una ragionevole visione delle cose è solo quando il comunismo eredita... l’ideale del progresso associato allo sviluppo, oggi al PIL, che diventa comunismo to- talitario e disciplinare» (Vattimo 2007: 107-9). Sfrondato dell’economicismo il comunismo si presenterebbe nel suo assetto originario, quello di una combinazione di “elettrificazione e soviet” mosso soltanto da un ideale di emancipazione. Perché il rapporto tra elettrificazione e soviet, tra tecnica e gestione politica resti fondamentalmente libertario, è necessario che accanto al riconoscimento delle conoscenze oggettive, necessarie perché l’elettrificazione funzioni, ci sia anche quello del carattere soggettivo-discrezionale del soviet: «Il soviet, però, è sovrano, rispetta la “natura” solo nella misura in cui gli serve per costruire una società libera dal dominio» (ivi: 120). Visto che «Una volta conosciuta l’esperienza sovietica degli anni di Stalin e seguenti, nessuno può più in buona fede identificare il comunismo con questa sua immagine deformata» (ivi: 107), l’indicazione essenziale per il recupero del buon comunismo originario è «riassumibile brutalmente così: non si dà comunismo libertario, “sovietico”, senza nichilismo e rifiuto della metafisica» (ivi: 122).
description: Trópos, V. 1 N. Speciale (2008): L'apertura del presente. Sull'ontologia ermeneutica di Gianni Vattimo
Multi-dark soliton solutions of the two-dimensional multi-component Yajima-Oikawa systems
Creators: name: Chen, Junchao
name: Chen, Yong
name: Feng, Bao-Feng
name: Maruno, Ken-ichi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences
subject: 35C08, 35Q51, 37K40

description: We present a general form of multi-dark soliton solutions of two-dimensional multi-component soliton systems. Multi-dark soliton solutions of the two-dimensional (2D) and one-dimensional (1D) multi-component Yajima-Oikawa (YO) systems, which are often called the 2D and 1D multi-component long wave-short wave resonance interaction systems, are studied in detail. Taking the 2D coupled YO system with two short wave and one long wave components as an example, we derive the general $N$-dark-dark soliton solution in both the Gram type and Wronski type determinant forms for the 2D coupled YO system via the KP hierarchy reduction method. By imposing certain constraint conditions, the general $N$-dark-dark soliton solution of the 1D coupled YO system is further obtained. The dynamics of one dark-dark and two dark-dark solitons are analyzed in detail. In contrast with bright-bright soliton collisions, it is shown that dark-dark soliton collisions are elastic and there is no energy exchange among solitons in different components. Moreover, the dark-dark soliton bound states including the stationary and moving ones are discussed. For the stationary case, the bound states exist up to arbitrary order, whereas, for the moving case, only the two-soliton bound state is possible under the condition that the coefficients of nonlinear terms have opposite signs.
description: 35 pages, 8 figures
SnowApp-ilmastopalvelu Pohjois-Suomen hiihtokeskuksille
Creators: name: Mettiäinen, Ilona
Publisher: name: Zenodo
Year: 2020
Subjects: ilmastopalvelu
climate service
kestävä matkailu
climate adaptation
ilmastonmuutokseen sopeutuminen
sustainable tourism
winter tourism
talvimatkailu
hiihtokeskukset
ski resorts

description: Presentation at the "Ilmastonmuutokseen sopeutuminen Arktisella alueella" workshop on 28.10.2020. Organized by ACAF project, Natural Resources Institute Finland (LUKE).
Ilmastopalvelun yhteissuunnittelu Pohjois-Suomen talvimatkailualalle
Creators: name: Mettiäinen, Ilona
Publisher: name: Zenodo
Year: 2020
Subjects: ilmastopalvelu
climate service
kestävä matkailu
sustainable tourism
ilmastonmuutokseen sopeutuminen
climate adaptation
ski resorts
hiihtokeskukset

description: Presentation to the Energiatehokas Arktinen lumi (ERDF) project's steering committee in their meeting on 29.5.2020.
Fractional Hall Conductivity and Spin-c Structure in Solvable Lattice Hamiltonians
Creators: name: Han, Zhaoyu
name: Chen, Jing-Yuan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The Kapustin-Fidkowski no-go theorem forbids $U(1)$ symmetric topological orders with non-trivial Hall conductivity in (2+1)d from admitting commuting projector Hamiltonians, where the latter is the paradigmatic method to construct exactly solvable lattice models for topological orders. Even if a topological order would intrinsically have admitted commuting projector Hamiltonians, the theorem forbids so once its interplay with $U(1)$ global symmetry which generates Hall conductivity is taken into consideration. Nonetheless, in this work, we show that for all (2+1)d $U(1)$ symmetric abelian topological orders of such kind, we can construct a lattice Hamiltonian that is controllably solvable at low energies, even though not "exactly" solvable; hence, this no-go theorem does not lead to significant difficulty in the lattice study of these topological orders. Moreover, for the fermionic topological orders in our construction, we introduce the lattice notion of spin-c structure -- a concept important in the continuum that has previously not been adequately introduced in the lattice context.
description: v3: 26 pages, published version
Non-equilibrium statistical field theory for classical particles: Basic kinetic theory
Creators: name: Viermann, Celia
name: Fabis, Felix
name: Kozlikin, Elena
name: Lilow, Robert
name: Bartelmann, Matthias
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Recently Mazenko and Das and Mazenko introduced a non-equilibrium field theoretical approach to describe the statistical properties of a classical particle ensemble starting from the microscopic equations of motion of each individual particle. We use this theory to investigate the transition from those microscopic degrees of freedom to the evolution equations of the macroscopic observables of the ensemble. For the free theory, we recover the continuity and Jeans equations of a collisionless gas. For a theory containing two-particle interactions in a canonical perturbation series, we find the macroscopic evolution equations to be described by the Born-Bogoliubov-Green-Kirkwood-Yvon hierarchy (BBGKY hierarchy) with a truncation criterion depending on the order in perturbation theory. This establishes a direct link between the classical and the field-theoretical approaches to kinetic theory that might serve as a starting point to investigate kinetic theory beyond the classical limits.
description: 13 pages, 1 figures, Phys. Rev. E, volume 91, June 2015
Alla ricerca del Vattimo fuggente
Creators: name: Mastroianni, Roberto
Publisher: name: Trópos
Year: 2023

description: La «leggerezza» è la prima delle proposte per il nuovo millennio che Calvino affida alle «Lezioni Americane». In essa la contrapposizione «leggerezza-peso» si articola in un attraversamento mitologico, che vede Perseo (la leggerezza) opporsi alla Gorgone (la pesantezza), metafore di forze che da sempre si affrontano nella storia della letteratura, raccontando una realtà in cui «tutto può trasformarsi in nuove forme», in cui «la conoscenza del mondo è dissoluzione della compattezza del mondo», in cui «c’è parità essenziale tra tutto ciò che esiste, contro ogni gerarchia di poteri e di valori». Insomma, sembra che la leggerezza calviniana, come prospettiva con cui guardare alla pesantezza della realtà, al linguaggio ed alla letteratura nel nuovo millennio, sia molto simile a quel nichilismo ermeneutico, per il quale «non ci sono fondamenti ultimi davanti a cui la nostra libertà debba fermarsi, come invece hanno sempre preteso di farci credere le autorità di ogni tipo che volevano comandare proprio in nome di queste strutture ultime». Un pensiero che si fa spazio di emancipazione dalle strutture metafisiche e dal portato di violenza che ad esse si accompagna.
description: Trópos, V. 1 N. Speciale (2008): L'apertura del presente. Sull'ontologia ermeneutica di Gianni Vattimo
Additional file 1 of Polycyclic aromatic hydrocarbon exposure effects on trajectories of maternal and adolescent mental health
Creators: name: DeSerisy, Mariah
name: Salas, Leilani
name: Akhundova, Emiliya
name: Pena, Dahiana
name: Cohen, Jacob W.
name: Pagliaccio, David
name: Herbstman, Julie
name: Rauh, Virginia
name: Margolis, Amy E.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biotechnology
Science Policy
Mental Health

description: Supplementary material 1