cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Проповедь об успении Девы Марии из «Исландской книги проповедей» (предисловие и перевод)
Creators: name: ГОЛОВАНЕНКО ДЕНИС АНДРЕЕВИЧ
Publisher: name: Vox medii aevi
Year: 2019
Subjects: Дева Мария; Исландия; «Исландская книга проповедей»; проповедь; успение

description: Проповедь об успении Девы Марии (Assumptio sancte Marie) входит в состав сборника, известного в историографии как «Исландская книга проповедей». Составленная, по всей видимости, до 1200 г., проповедь является одним из образцов ранней исландской письменности и христианской литературы. Перед составителем проповеди стояла нетривиальная задача: выразить новые понятия и описать новые явления непривычным к ним языком, и результат ее решения, с одной стороны, напоминает разговорную речь родовых саг, а с другой — это достаточно темный ученый стиль, стремящийся повторить, по-видимому, латинские риторические приемы. Неясно, предназначалась ли эта проповедь для чтения перед аудиторией или являлась своего рода образцом и опорой для проповедника. В пользу последнего говорит неоднородная структура «Книги» в целом, а также наличие в ней текстов нелитургического характера, в то время как в пользу первого — использование местоимений первого лица и прямых обращений к слушателям. В этой публикации предлагается перевод проповеди, снабженный краткими вступительными замечаниями.
The SAMI Galaxy Survey: Data Release Two with absorption-line physics value-added products
Creators: name: Scott, Nicholas
name: van de Sande, Jesse
name: Croom, Scott M.
name: Groves, Brent
name: Owers, Matt S.
name: Poetrodjojo, Henry
name: D'Eugenio, Francesco
name: Medling, Anne M.
name: Barat, Dilyar
name: Barone, Tania M.
name: Bland-Hawthorn, Joss
name: Brough, Sarah
name: Bryant, Julia
name: Cortese, Luca
name: Foster, Caroline
name: Green, Andrew W.
name: Oh, Sree
name: Colless, Matthew
name: Drinkwater, Michael J.
name: Driver, Simon P.
name: Goodwin, Michael
name: Gunawardhana, Madusha L.P.
name: Federrath, Christoph
name: Harischandra, Lloyd
name: Jin, Yifei
name: Lawrence, J. S.
name: Lorente, Nuria P.
name: Mannering, Elizabeth
name: O'Toole, Simon
name: Richards, Samuel N.
name: Sanchez, Sebastian F.
name: Schaefer, Adam L.
name: Sealey, Katrina
name: Sharp, Rob
name: Sweet, Sarah
name: Taranu, Dan S.
name: Varidel, Mathew
Publisher: name: Swinburne
Year: 2024

description: We present the second major release of data from the Sydney - Australian Astronomical Observatory Multi-Object Integral Field Spectrograph (SAMI) Galaxy Survey. Data Release Two includes data for 1559 galaxies, about 50 per cent of the full survey. Galaxies included have a redshift range 0.004 < z < 0.113 and a large stellar mass range 7.5 < log (M-*/M-circle dot) < 11.6. The core data for each galaxy consist of two primary spectral cubes covering the blue and red optical wavelength ranges. For each primary cube, we also provide three spatially binned spectral cubes and a set of standardized aperture spectra. For each core data product, we provide a set of value-added data products. This includes all emission line value-added products from Data Release One, expanded to the larger sample. In addition, we include stellar kinematic and stellar population value-added products derived from absorption line measurements. The data are provided online through Australian Astronomical Optics' Data Central. We illustrate the potential of this release by presenting the distribution of similar to 350 000 stellar velocity dispersion measurements from individual spaxels as a function of R/R e , divided in four galaxy mass bins. In the highest stellar mass bin [log (M-*/M-circle dot) > 11], the velocity dispersion strongly increases towards the centre, whereas below log (M-*/M-circle dot) < 10 we find no evidence for a clear increase in the central velocity dispersion. This suggests a transition mass around log (M-*/M-circle dot) similar to 10 for galaxies with or without a dispersion-dominated bulge.
Споры о падении Рима: от «старого порядка» до создания «поздней Античности»
Creators: name: ИЭН ВУД
Publisher: name: Vox medii aevi
Year: 2019
Subjects: германские варвары; историография; национализм; падение Римской империи; поздняя Античность.

description: Взгляды на проблему «падения Рима» неизменно отражали главные политические темы периодов, в которые они появлялись. Во Франции начала XVIII в. «падение Рима» обсуждалось в контексте споров об абсолютизме и правах аристократии, которая, как предполагалось, вела свое происхождение от варварских новопоселенцев. В эпоху Великой французской революции эти пришельцы считались и борцами за свободу, и предками знати. Эти противоречащие друг другу точки зрения были отвергнуты Огюстеном Тьерри, подчеркивающим угнетенное положение исконного населения. Данную модель позже взял на вооружение итальянец Алессандро Мандзони, и она стала элементом в интеллектуальной атмосфере Рисорджименто и обсуждении проблемы присутствия чужестранцев на итальянской земле. В качестве аргумента против подобного прочтения с его этническими и классовыми подтекстами было выдвинуто прочтение религиозное: после уничтожения варварами в сущности прогнившего римского мира, цивилизация восстала из пепла стараниями церкви. Хотя подобные толкования выдвигались и позже, в конце XIX в. споры вращались в основном вокруг роли германских народов. Исследователи, затронутые движением немецкого объединения, видели варваров преимущественно в националистическом свете. Другие, напротив, занижали значимость их вторжений и настаивали на внутренней слабости Римской империи, одновременно указывая на преемственность с постримским периодом. Из этих двух интерпретаций националистическая оказалась сильнее в период двух мировых войн. Вслед за поражением Рейха рассматривать варваров в положительном ключе стало невозможно: они либо превратились в разрушителей, либо практически исчезли из поля зрения историков. Акцент на культурных достижениях позднеи постримского периодов создал почву для более позитивного прочтения в 1970-х гг. понятия «поздней Античности», хотя старые трактовки живы и сегодня, частично в связи с обсуждением места США в мировом порядке. Другими словами, актуальная политическая и социальная повестка дня неизбывно обращалась к «падению Рима» — историографию невозможно отделить от ее контекста.
Microaggressions: An Approach to Understanding the Health of Workers in Long‐Term Care Settings
Creators: name: Eckert, J Kevin
name: Harris Wallace, Brandy
name: Zimmerman, Sheryl
name: Roth, Erin G
Publisher: name: Wiley
Year: 2016

description: To the Editor: In recent news, a nurse filed suit against her
employer, an assisted living organization, alleging that the
organization “failed to protect her from abusive racism
from residents.”1 Claims of racism in long-term care
(LTC) settings have been reported by minority workers for
more than two decades.2 Regrettably, the literature in this
area is limited, particularly research addressing the health
outcomes of minority staff resulting from negative racial
interactions in the workplace.
Dynamique du nationalisme québécois, 1960--1976
Creators: name: Kapenda, Marc
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: History, Canadian.
subject: Canadian Studies.

description: Le mouvement nationaliste québécois persiste malgré un contrôle social fédéral hostile à son égard et la mondialisation qui tend à homogénéiser la culture. Quels facteurs soutiennent cette persistance? À l'aide de la théorie des mouvements sociaux de Neil Smelser, un regard sur la période 1960 à 1976 permet d'établir que le nationalisme québécois est un mouvement social axé sur des valeurs. Il tire sa conductibilité dans une cohésion sociale et est soutenue par plusieurs facteurs. Des tensions sociales dans la communauté francophone du Québec, des représentations qui y sont formulées, des motivations et des moyens qui sont développés en vue de résoudre les tensions, le leadership ainsi que les effets du contrôle social interviennent dans une dynamique. Chacun de ces facteurs, ajouté à la dynamique, contribué à déterminer la persistance du mouvement. Tant que la dynamique demeurera, le Parti Québécois, le leadership nationaliste, peut maintenir la mobilisation en faveur de l'objectif de l'autonomie nationale, présentée comme une solution adéquate aux tensions de divers niveaux (politiques, économiques, culturelles et sociales), Plutôt qu'un contrôle social hostile, les négociations politiques offriraient de meilleures chances d'intégration constitutionnelle des aspirations nationalistes.
ADSL-VDSL interference mitigation for the fiber to the cabinet architecture using adaptive filtering and the longitudinal signal as a reference
Creators: name: Kamkar-Parsi, A. Homayoun
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Engineering, Electronics and Electrical.

description: With architectures such as fiber to the cabinet, the possible combination of shorter lines deployed from the cabinet with longer lines deployed from the Central Office in the same bundle can cause the far-end crosstalk from the transmitters located at the cabinet to severely degrade the performance of the long lines. External interference (including crosstalk) mostly couples to the twisted-pair line as a longitudinal signal, and then leaks to differential mode because of the lack of ideal line balance. This thesis offers a possible solution to mitigate crosstalk impairments worsened by the fiber to the cabinet architecture. This thesis uses the longitudinal signal as a reference to an adaptive wideband crosstalk canceller, aiming to decrease the crosstalk in the corrupted differential signal. Simulations show that the canceller can substantially reduce the crosstalk in the differential signal and evaluates three distinct adaptive algorithms for convergence speed and complexity.
Methodologic Issues when Estimating Risks in Pharmacoepidemiology
Creators: name: Gokhale, Mugdha
name: Hester, Laura L.
name: Lesko, Catherine R.
name: Edwards, Jessie K.
Publisher: name: Springer Nature
Year: 2016

description: Risk is an important parameter to describe the occurrence of health outcomes over time. However, many outcomes of interest in healthcare settings, such as disease incidence, treatment initiation, and cause-specific mortality, may be precluded from occurring by other events, often referred to as competing events. Here, we review straightforward approaches to estimate risk in the presence of competing events.Recent Findings We illustrate the application of these methods using timely examples in pharmacoepidemiologic research and compare results to those obtained using analytic simplifications commonly used to handle competing events. Summary These examples demonstrate how the analytic methods used to account for competing events affect the interpretation of results from pharmacoepidemiologic studies.
The role of prostaglandin EP receptors in a model of glomerulonephritis
Creators: name: Rahal, Sherine S
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Biology, Molecular.

description: Prostaglandin E2 (PGE2) interacts with four E-Prostanoid (EP) receptor subtypes---designated EP1--4 . In glomerulonephritis (GN), a renal inflammatory disease, inhibition of enhanced renal PGE2 synthesis by nonsteroidal-anti-inflammatory drugs (NSAIDs), results in both beneficial anti-proteinuric effects and deleterious side effects on renal blood flow (RBF) and Na+ homeostasis, implying that one or more EP subtypes may mediate these actions. We set out to investigate the role of the EP1 receptor in GN since it localizes to the collecting duct, where it may regulate Na+ homeostasis, in podocytes and mesangial cells, where it could alter the permeability of the glomerulus, and in arterioles, where EP, receptors may induce vasoconstriction thereby reducing RBF. A mouse model of GN was induced in wildtype (wt) and EP1-/- mice using an anti-rat-glomerular basement membrane (anti-GBM) antibody. Proteinuria was similar in GN wt and GN EP1-/- groups thereby negating a role for this subtype in modulating filtration barrier permeability. (Abstract shortened by UMI.)
Regulatory reform: A case study of the Regulatory Advisory Committee (RAC) and the Canadian Environmental Assessment Act.
Creators: name: Alexander, Lawrence.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1996
Subjects: subject: Law.

description: This paper examines a consensus-based approach to regulation making known as "regulation negotiation" or "regneg," and pursues the question, can regneg improve the performance of the federal regulatory process? Successfully implemented by the United States Environmental Protection Agency, regneg allows parties likely to be affected by a regulation to negotiate the substance of it. Although its use is rare in Canada, a similar process was used to help develop key regulations under the Canadian Environmental Assessment Act. The paper argues that the performance of any regulatory process can be measured by its ability to accommodate the views of a more diverse range of interests, improve the quality of regulations, and hold regulation makers to a higher standard of accountability. Based on the U.S. and Canadian experience, the paper suggests that in certain circumstances, and with some refinements, regneg is capable of improving the regulatory process in all of these areas.
Integrated analysis of the multifunctional protein Aft1p
Creators: name: Berthelet, Sharon
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Chemistry, Biochemistry.

description: The Saccharomyces cerevisiae transcription factor Aft1p has an established role under iron-deplete conditions in the induction of genes involved in iron acquisition and utilization. Recent studies have indicated that Aft1p is required for faithful chromosome transmission and aft1Delta mutant cells have defects in cell cycle progression. This suggests that Aft1p has additional, but undefined, cellular roles under iron-replete conditions. To explore the role of Aft1p, two genome-wide screens were utilized to identify nonessential deletion mutants that are unable to tolerate defects in Aft1p function, and an Aft1p physical protein-protein interaction map was constructed using affinity purification and mass spectrometry. Our integrative analysis has produced an extended network of genetic and physical interactions, which connect Aft1p to a wide range of cellular functions including the RIM101 pH response pathway, DNA replication, and DNA repair. Our results establish that Aft1p is multifunctional with broad cellular roles.
Konzept der akademischen Ausbildung am Bundeswehrkrankenhaus Ulm
Creators: name: Becker, Heike
name: Claußsnitzer, Christian
name: Friemert, Benedikt
name: Grobecker, Susanne
name: Gümbel, Hermann
name: Häfner, Simon
name: Hoffmann, Ralf
name: Kremmeter, Susanne
name: Kulla, Martin
name: Lampl, Lorenz
name: Lorenz, Kai
name: Martinschek, Andreas
name: Mauer, Uwe
name: Metrikat, Jens
name: Sparwasser, Christoph
name: Tisch, Matthias
name: Wilde, Frank
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: Lehre
subject: Studium
subject: Medizin
subject: Humanmedizin
subject: DDC 610 / Medicine & health
subject: Education, medical, graduate; Germany
subject: Praktisches Jahr
subject: Medizinstudium

description: Das Manuskript "Konzept der akademischen Ausbildung am Bundeswehrkrankenhaus Ulm" dient der Information der Studierenden im Praktischen Jahr. Es enthält eine Übersicht der klinischen Abteilungen des Bundeswehrkrankenhauses Ulm sowie deren Ausbildungskonzepte und Ansprechpartner. Es wird im jährlichen Rhythmus überarbeitet und im A5 Format gedruckt. (Auflage ca, 150 Exemplare/ Jahr)
Factors Associated with PMTCT Cascade Completion in Four African Countries
Creators: name: Tita, Alan T. N.
name: Kasaro, Margaret
name: Ekouevi, Didier Koumavi
name: Welty, Thomas K.
name: Chi, Benjamin H.
name: Westfall, Andrew O.
name: Dionne-Odom, Jodie
name: Tih, Pius M.
Publisher: name: Hindawi
Year: 2016

description: Background. Many countries are working to reduce or eliminate mother-to-child transmission (MTCT) of HIV. Prevention efforts have been conceptualized as steps in a cascade but cascade completion rates during and after pregnancy are low. Methods. A cross-sectional survey was performed across 26 communities in Cameroon, Cote d'Ivoire, South Africa, and Zambia. Women who reported a pregnancy within two years were enrolled. Participant responses were used to construct the PMTCT cascade with all of the following steps required for completion: at least one antenatal visit, HIV testing performed, HIV testing result received, initiation of maternal prophylaxis, and initiation of infant prophylaxis. Factors associated with cascade completion were identified using multivariable logistic regression modeling. Results. Of 976 HIV-infected women, only 355 (36.4%) completed the PMTCT cascade. Although most women (69.2%) did not know their partner's HIV status; awareness of partner HIV status was associated with cascade completion (aOR 1.4, 95% CI 1.01-2.0). Completion was also associated with receiving an HIV diagnosis prior to pregnancy compared with HIV diagnosis during or after pregnancy (aOR 14.1, 95% CI 5.2-38.6). Conclusions. Pregnant women with HIV infection in Africa who were aware of their partner's HIV status and who were diagnosed with HIV before pregnancy were more likely to complete the PMTCT cascade.
Grassland Management Influences the Response of Soil Respiration to Drought
Creators: name: Moinet, Gabriel Y. K.
name: Midwood, Andrew J.
name: Hunt, John E.
name: Rumpel, Cornelia
name: Millard, Peter
name: Chabbi, Abad
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Increasing soil carbon stocks in agricultural grasslands has a strong potential to mitigate climate change. However, large uncertainties around the drivers of soil respiration hinder our ability to identify management practices that enhance soil carbon sequestration. In a context where more intense and prolonged droughts are predicted in many regions, it is critical to understand how different management practices will temper drought-induced carbon losses through soil respiration. In this study, we compared the impact of changing soil volumetric water content during a drought on soil respiration in permanent grasslands managed either as grazed by dairy cows or as a mowing regime. Across treatments, root biomass explained 43% of the variability in soil respiration (p < 0.0001). Moreover, analysis of the isotopic composition of CO₂ emitted from the soil, roots, and root-free soil suggested that the autotrophic component largely dominated soil respiration. Soil respiration was positively correlated with soil water content (p = 0.03) only for the grazed treatment. Our results suggest that the effect of soil water content on soil respiration was attributable mainly to an effect on root and rhizosphere activity in the grazed treatment. We conclude that farm management practices can alter the relationship between soil respiration and soil water content.
Supplementary document for A fast, non-iterative algorithm for quantitative integration of X-ray differential phase-contrast images - 4940956.pdf
Creators: name: Massimi, Lorenzo
name: Buchanan, Ian
name: Astolfo, Alberto
name: Endrizzi, Marco
name: Olivo, A
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: A latex version is available for this document
TC10, a mammalian Rho GTPase responsible for actin cytoskeleton reorganization and cardiac hypertrophy in the murine heart
Creators: name: Lalonde, Julie Kathleen
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Biology, Molecular.

description: Rho guanosine triphosphatases (GTPases) act as molecular switches, cycling between two conformational states: an active, GTP-bound state and an inactive, GDP-bound state to control many complex cellular events in eukaryotic cells. Many Rho GTPases, including RhoA, Cdc42 and Rac1, have been extensively characterized and are involved in actin reorganization, activation of MAPK cascades, cell cycle progression, cellular proliferation, invasion, differentiation and apoptosis. TC10 was identified and classified as a Rho GTPase over ten years ago, however the precise role of this protein, which is highly expressed in cardiac and skeletal muscle, has only recently been explored in vitro and remains unexplored in vivo. Based on the unique expression pattern of TC10, we set out to investigate the role of TC10 by generating transgenic mice over-expressing activated TC10Q75L under the control of the cardiac-specific alpha-myosin heavy chain promoter. Transgenic mice expressing high levels of TC10Q75L showed pronounced atrial enlargement, evidence of left ventricular hypertrophy and diminished cardiomyocyte membrane integrity. In vitro, transgenic primary cardiomyocytes showed marked reorganization of the actin cytoskeleton, leading to the formation of actin-containing filopodial extensions, loss of stress fibers and actin aggregation. Together, these data suggest that TC10 functions to regulate cellular signalling to the actin cytoskeleton and processes associated with cell growth, leading to cardiac hypertrophy in TC10Q75L transgenic mice.
Design and implementation of an agent-based Web service composition framework
Creators: name: Marquez-Rangel, Oscar
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Computer Science.

description: This thesis proposes the design of a Web service composition framework in which individual Web services are represented by software agents that collaborate to create composite services. The design includes the language to define composite services, the protocol that software agents follow when executing composite services and the architecture of the proposed framework. The proposed architecture provides: (i) the incorporation of standard technologies for service discovery into a dynamic service-discovery process; (ii) high levels of scalability and flexibility without requiring the service provider to host additional modules; and (iii) the incorporation of composite services that are successfully executed even when negligible individual services fail. The proposed framework was evaluated with different sets of users that simultaneously requested the same composite service. An improvement to the basic architecture was made to decrease the processing times when the number of users is increased. (Abstract shortened by UMI.)
Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients
Creators: name: Öztürk, Selcen
name: Paul, Yashna
name: Afzal, Saira
name: Gil-Farina, Irene
name: Jauch, Anna
name: Bruch, Peter-Martin
name: Kalter, Verena
name: Hanna, Bola
name: Arseni, Lavinia
name: Roessner, Philipp M.
name: Schmidt, Manfred
name: Stilgenbauer, Stephan
name: Dietrich, Sascha
name: Lichter, Peter
name: Zapatka, Marc
name: Seiffert, Martina
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Cancer genomics
subject: Cancer models
subject: Chronic lymphocytic leukaemia
subject: CHRONIC LYMPHOCYTIC-LEUKEMIA
subject: TRANSGENIC MOUSE
subject: TYROSINE KINASE
subject: MODEL
subject: PROGRESSION
subject: EVOLUTION
subject: FLT3
subject: CHECKPOINT
subject: EXPRESSION
subject: MUTATIONS
subject: DDC 610 / Medicine & health

description: Abstract Chronic lymphocytic leukemia (CLL) is a B-cell malignancy mainly occurring at an advanced age with no single major genetic driver. Transgenic expression of TCL1 in B cells leads after a long latency to a CLL-like disease in aged Eµ-TCL1 mice suggesting that TCL1 overexpression is not sufficient for full leukemic transformation. In search for secondary genetic events and to elucidate the clonal evolution of CLL, we performed whole exome and B-cell receptor sequencing of longitudinal leukemia samples of Eµ-TCL1 mice. We observed a B-cell receptor stereotypy, as described in patients, confirming that CLL is an antigen-driven disease. Deep sequencing showed that leukemia in Eµ-TCL1 mice is mostly monoclonal. Rare oligoclonality was associated with inability of tumors to develop disease upon adoptive transfer in mice. In addition, we identified clonal changes and a sequential acquisition of mutations with known relevance in CLL, which highlights the genetic similarities and therefore, suitability of the Eµ-TCL1 mouse model for progressive CLL. Among them, a recurrent gain of chromosome 15, where Myc is located, was identified in almost all tumors in Eµ-TCL1 mice. Interestingly, amplification of 8q24, the chromosomal region containing MYC in humans, was associated with worse outcome of patients with CLL.
description: Clonal evolution and genomic alterations in the Eµ-TCL1 mouse model mirror human CLL and identify Myc as oncogenic hit associated with disease progression in patients.
Transition theorems and almost sure invariance principles for strong martingales.
Creators: name: Fang, Youjian.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Mathematics.

description: In this thesis we establish almost sure invariance principles (ASIP's) for strong martingales indexed by two parameters. The method we use is that developed by Berkes and Philipp (Ann. Prob., 7, 1979). This thesis is organized in four chapters. In Chapter 1, we give a review of invariance principles. We introduce the origin of the concept of the invariance principle, describe the main methods for proving the ASIP's and state some basic results of the almost sure invariance principle. In Chapter 2, we prove some "transition theorems" which turn two-parameter strong martingales into one-parameter martingales and can help us to prove the ASIP's for two-parameter strong martingales. We also give several simple applications of the transition theorems, such as maximal inequalities with exponential bounds for two-parameter strong martingales and the Prohorov distance between the law of a two-parameter strong martingale and some appropriate normal law. In Chapter 3, we prove our main theorem--the almost sure invariance principle for two-parameter strong martingales and show some applications, including the functional law of the iterated logarithm for two-parameter strong martingales. In Chapter 4--the appendix, we state some known results we want to use and give the proofs of Theorem 2.2.1 in Chapter 2 and Lemma 3.2.10 in Chapter 3.
Supplementary document for A fast, non-iterative algorithm for quantitative integration of X-ray differential phase-contrast images - 4940956.pdf
Creators: name: Massimi, Lorenzo
name: Buchanan, Ian
name: Astolfo, Alberto
name: Endrizzi, Marco
name: Olivo, A
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: A latex version is available for this document
Measuring gait-event-related brain potentials (gERPs) during instructed and spontaneous treadmill walking: technical solutions and automated classification through artificial neural networks
Creators: name: Herbert, Cornelia
name: Munz, Michael
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Human gait analysis
subject: Motor potentials
subject: Event-related potentials (ERPs)
subject: Gait-ERPs
subject: Desynchronization
subject: DDC 530 / Physics
subject: DDC 540 / Chemistry & allied sciences
subject: DDC 620 / Engineering & allied operations
subject: Neural networks (Computer science)
subject: Machine learning
subject: Locomotion
subject: Cognition
subject: Attention
subject: Gait
subject: Electroencephalography
subject: Neuronales Netz
subject: Maschinelles Lernen
subject: Elektroencephalographie

description: The investigation of the neural correlates of human gait, as measured by means of non-invasive electroencephalography (EEG), is of central importance for the understanding of human gait and for novel developments in gait rehabilitation. Particularly, gait-event-related brain potentials (gERPs) may provide information about the functional role of cortical brain regions in human gait control. The purpose of this paper is to explore possible experimental and technical solutions for time-sensitive analysis of human gait ERPs during spontaneous and instructed treadmill walking. A solution (hardware/software) for synchronous recording of gait and EEG data was developed, tested and piloted. The solution consists of a custom-made USB synchronization interface, a time-synchronization module, and a data-merging module, allowing the temporal synchronization of recording devices, time-sensitive extraction of gait markers for the analysis of gERPs, and the training of artificial neural networks. In the present manuscript, the hardware and software components were tested with the following devices: A treadmill with an integrated pressure plate for gait analysis (zebris FDM-T) and an Acticap non-wireless 32-channel EEG system (Brain Products GmbH). The usability and validity of the developed solution was investigated in a pilot study (n = 3 healthy participants, n = 3 females, mean age = 22.75 years). The recorded continuous EEG data were segmented into epochs according to the detected gait markers for the analysis of gERPs. Finally, the EEG epochs were used to train a deep learning artificial neural network as classifier of gait phases. The results obtained in this pilot study, although preliminary, support the feasibility of the solution for the application of gait-related EEG analysis.
Performance analysis and robustness of the ATM adaptation layer 2 over wireless ATM networks.
Creators: name: Villasenor Gonzalez, Luis Armando.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Engineering, Electronics and Electrical.

description: The wireless and personal communication systems are experiencing an enormous growth due to recent advancements in wireless networking technologies. At the same time the cellular network infrastructure around the world is being upgraded to support the 3rd generation wireless communication networks, as defined by the International Mobile Telecommunications for the year 2000 (IMT-2000) and the Universal Mobile Telecommunication Systems (UMTS) standards. As a result there is great interest in evaluating diverse technologies that can be used to handle the heterogeneous traffic types and at the same time be able to provide quality of service guarantees and ATM has been identified as an ideal transport technology for this type of networks. The research presented in this thesis details the use of the ATM Adaptation Layer 2 (AAL2) standard, which is used to adapt low data rate and delay sensitive traffic in ATM networks. In this work we are interested in evaluating the performance of the AAL2 standard over error-prone wireless links. Therefore we are interested in proposing a mechanism to improve the performance that is observed at the AAL2 layer. The study begins by evaluating diverse analytical models to characterize the bit error process at the physical layer over error-prone links. This study has identified that the Finite State Markov Chain (FSMC) models provide a suitable analytical work frame to evaluate the impact of bit errors at the higher protocol layers, such as the AAL2. Based on the FSMC models we derive analytical expressions to evaluate the impact of bit errors at the AAL2 layer and numerical results are obtained to evaluate the performance of the AAL2 standard over the error-prone links. Later the analytical expressions are used to evaluate the performance improvements at the AAL2 layer when implementing diverse techniques that are commonly used to improve system performance. Such techniques include the use of Forward Error Correction codes and diversity techniques. Finally, a robust frame format is proposed for the AAL2 standard. The proposed frame format improves the performance of the AAL2 standard by introducing a robust mechanism for the delineation of AAL2 packets. In addition, the proposed mechanism can reduce the overhead introduce by the header fields that are required to achieve the delineation of the AAL2 packets inside the payload of the ATM cells.
Bartonella Endocarditis and Pauci-Immune Glomerulonephritis
Creators: name: Timpone, Joseph G
name: Raybould, Alison L
name: Lipkowitz, Michael S
name: Morales, Megan K
name: Zaheer, Misbah
name: Kumar, Princy N
name: Raybould, Jillian E
Publisher: name: Wolters Kluwer
Year: 2016

description: Among culture-negative endocarditis in the United States, Bartonella species are the most common cause, with Bartonella henselae and Bartonella quintana comprising the majority of cases. Kidney manifestations, particularly glomerulonephritis, are common sequelae of infectious endocarditis, with nearly half of all Bartonella patients demonstrating renal involvement. Although a pauci-immune pattern is a frequent finding in infectious endocarditis-associated glomerulonephritis, it is rarely reported in Bartonella endocarditis. Anti-neutrophil cytoplasmic antibody (ANCA) positivity can be seen with many pathogens causing endocarditis and has been previously reported with Bartonella species. In addition, ANCA-associated vasculitis can also present with renal and cardiac involvement, including noninfectious valvular vegetations and pauci-immune glomerulonephritis. Given the overlap in their clinical presentation, it is difficult to differentiate between Bartonella endocarditis and ANCA-associated vasculitis but imperative to do so to guide management decisions. We present a case of ANCA-positive Bartonella endocarditis with associated pauci-immune glomerulonephritis that was successfully treated with medical management alone.
Lianas and trees from a seasonally dry and a wet tropical forest did not differ in embolism resistance but did differ in xylem anatomical traits in the dry forest.
Creators: name: Smith-Martin, Chris M.
name: Jansen, Steven
name: Brodribb, Timothy J.
name: Medina-Vega, José A.
name: Lucani, Christopher
name: Huppenberger, Andrea
name: Powers, Jennifer S.
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: canopy crane
subject: plant functional traits
subject: plant hydraulic strategies
subject: P50 optical vulnerability technique
subject: rainfall gradient
subject: woody plant growth forms
subject: xylem intervessel pit membranes
subject: DDC 570 / Life sciences
subject: DDC 580 / Botanical sciences
subject: Panama, Isthmus of (Panama)
subject: Dürreresistenz

description: One of the most prominent changes in neotropical forests has been the increase in abundance and size of lianas. Studies suggest that lianas have more acquisitive strategies than trees, which could allow them to take advantage of water more effectively when it is available in water-limited forests, but few studies compared across growth form (i.e., lianas vs. trees) and forest type (i.e., wet vs. seasonally dry). We measured hydraulic and anatomical traits of co-occurring lianas and trees that convey drought resistance (xylem embolism resistance and intervessel pit membranes) and water transport capacity (xylem vessel diameter and density) in a seasonally dry and a wet evergreen tropical forest to address: (1) Are there differences between vulnerability to embolisms (P50—water potential at 50% loss of hydraulic conductivity) and hydraulic safety margins (HSM) across growth form and forest type? (2) How do vessel diameter and density vary across growth form and forest type? (3) Are there differences in xylem intervessel pit membrane thickness across growth form and forest type and does it predict xylem embolism vulnerability in trees and lianas? We examined hydraulic and xylem anatomical traits of 32 species—eight lianas and eight trees in each forest type. We found no difference in P50 and HSMs between lianas and trees and between the wetter and drier forest. Dry forest lianas had 81% greater maximum vessel diameter and 125% greater range in vessel diameter sizes than dry forest trees but, there was no significant difference between life forms in the wet forest. Dry forest species had 50% greater vessel density and 30% greater maximum pit membrane thickness than wet forest ones. Maximum pit membrane thickness was correlated to P50 and HSMs. The main difference between lianas and trees occurred in the dry forest, where lianas had larger maximum xylem vessel size than trees, implying that they have proportionally greater hydraulic conductive capacity than the trees in seasonal forests.
The birth of a psychiatric orphan disorder: postpartum psychosis
Creators: name: Munk-Olsen, Trine
name: Bergink, Veerle
name: Di Florio, Arianna
Publisher: name: Elsevier
Year: 2016

description: To the Editor
February 29th is officially marked as “Rare Disease Day”. Hitherto, over 5,800 rare diseases
were officially recognized, but not a single adult psychiatric disorder. This leap year for the first
time postpartum psychosis is included in the list curated by Orphanet, the reference portal for
information on rare diseases.
Design and implementation of a Java H.263/G.726 decoder.
Creators: name: Leung, Spencer.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Engineering, Electronics and Electrical.

description: In this thesis, we present a decoder that is capable of performing real-time decoding of video and audio streams on Java-enabled platforms. We decompose the design phase into two stages: the declaration of design objectives and the proposition of a high level design. The design objectives are to build a decoder that is efficient, small in size, and adaptable to different platforms and network environments. The high level design is composed of key algorithms and major building blocks of the decoder. We document some challenges encountered during the implementation phase, some of which required revision of the initial design. We conduct test cases under some representative network environments to demonstrate the adaptability of the decoder. Lastly, we identify the work areas to be extended.
Factors affecting distance to the nearest physician in Canada: Changes from 1993-1999.
Creators: name: Amankwah, Nana Akwasi.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Health Sciences, Public Health.

description: Ability to pay for physician services is not a barrier to service in Canada, but travel distance may restrict some people's access, especially in rural areas. This thesis examines the distance to the nearest physician from a representative point within each of Canada's census enumeration areas in 1999, and the nature and extent of changes in these distances since 1993. The study is based on the 1999 postal codes of the 56,775 physicians in the Canadian Medical Association registry. Distance to the nearest physician has changed little since 1993; 87% of the population still live less than 5 km from the nearest physician. Distance to the nearest physician was greater in rural areas and small towns, in less urbanized provinces/territories, at higher latitudes, and in less urbanized low-income areas. Physicians-to-population ratios also decreased by 6% from 1993 to 1999.
Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study
Creators: name: Aousji, Oumayma
name: Feldengut, Simone
name: Antonucci, Stefano
name: Schön, Michael
name: Böckers, Tobias M.
name: Matschke, Jakob
name: Mawrin, Christian
name: Ludolph, Albert C.
name: Del Tredici, Kelly
name: Roselli, Francesco
name: Braak, Heiko
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Phosphorylated TDP-43
subject: Human spinal cord
subject: Synaptic loss
subject: pTDP-43
subject: DDC 610 / Medicine & health
subject: Amyotrophic lateral sclerosis
subject: Spinal cord
subject: Synaptophysin
subject: Synapses
subject: DNA-binding proteins
subject: Myatrophische Lateralsklerose
subject: Synapse
subject: Synaptophysin

description: Amyotrophic Lateral Sclerosis (ALS) is mainly characterized by the degeneration of corticospinal neurons and spinal α-motoneurons; vulnerable cells display prominent pTDP-43 inclusions. Evidence gathered from genetics, murine models, and iPSC-derived neurons point to the early involvement of synapses in the disease course and their crucial role in the pathogenic cascade. However, pathology studies, with specimens from large post-mortem cohorts, mapping the pattern of synaptic disturbances over clinical and neuropathological hallmarks of disease progression, are currently not available. Thus, the appearance and progression of synaptic degeneration in human ALS patients are currently not known, preventing a full validation of the murine and in vitro models. Here, we investigated the loss of synaptophysin-positive terminals in cervical, thoracic, and lumbar spinal cord samples from a retrospective cohort of n = 33 ALS patients and n = 8 healthy controls, and we correlated the loss of synapses against clinicodemographic features and neuropathological ALS stage. We found that, although dorsal and intermediate spinal cord laminae do not lose synapses, ALS patients displayed a substantial but variable loss of synapses in the ventral horn of lumbar and cervical spinal cord. The amount of synaptic loss was predicted by disease duration, by the clinical site of onset, and by the loss of α-motoneurons, although not by the fraction of pTDP-43-immunopositive α-motoneurons. Taken together, our findings validate the synaptic pathology observed in other models and suggest that pathogenic pathways unfolding in the spinal microenvironment are critical to the progressive disassembly of local synaptic connectivity.
The Large Early Galaxy Astrophysics Census (LEGA-C) Data Release 2: Dynamical and Stellar Population Properties of z ≲ 1 Galaxies in the COSMOS Field
Creators: name: Straatman, Caroline M.S.
name: Wel, Arjen Van Der
name: Bezanson, Rachel
name: Pacifici, Camilla
name: Gallazzi, Anna
name: Wu, Po Feng
name: Noeske, Kai
name: Barišić, Ivana
name: Bell, Eric F.
name: Brammer, Gabriel B.
name: Calhau, Joao
name: Chauke, Priscilla
name: Franx, Marijn
name: Houdt, Josha Van
name: Labbe, Ivo
name: Maseda, Michael V.
name: Munoz-Mateos, Juan C.
name: Muzzin, Adam
name: Sande, Jesse Van De
name: Sobral, David
name: Spilker, Justin S.
Publisher: name: Swinburne
Year: 2024

description: We present the second data release of the Large Early Galaxy Astrophysics Census (LEGA-C), an ESO 130-night public spectroscopic survey conducted with VIMOS on the Very Large Telescope. We release 1988 spectra with typical continuum S/N similar or equal to 20 angstrom(-1) of galaxies at 0.6 less than or similar to z less than or similar to 1.0, each observed for similar to 20 hr and fully reduced with a custom-built pipeline. We also release a catalog with spectroscopic redshifts, emission-line fluxes, Lick/IDS indices, and observed stellar and gas velocity dispersions that are spatially integrated quantities, including both rotational motions and genuine dispersion. To illustrate the new parameter space in the intermediate-redshift regime probed by LEGA-C, we explore relationships between dynamical and stellar population properties. The star-forming galaxies typically have observed stellar velocity dispersions of similar to 150 km s(-1) and strong H delta absorption (H delta(A) similar to 5 angstrom), while passive galaxies have higher observed stellar velocity dispersions (similar to 200 km s(-1)) and weak H delta absorption (H delta(A) similar to 0 angstrom). Strong [O III] 5007/H beta ratios tend to occur mostly for galaxies with weak H delta(A) or galaxies with higher observed velocity dispersion. Beyond these broad trends, we find a diversity of possible combinations of rest-frame colors, absorption-line strengths, and emission-line detections, illustrating the utility of spectroscopic measurements to more accurately understand galaxy evolution. By making the spectra and value-added catalogs publicly available we encourage the community to take advantage of this very substantial investment in telescope time provided by ESO.
The Binding Site Barrier Elicited by Tumor-Associated Fibroblasts Interferes Disposition of Nanoparticles in Stroma-Vessel Type Tumors
Creators: name: Miao, Lei
name: Zhang, Lu
name: Milowsky, Matthew I.
name: Xu, Feifei
name: Newby, Jay M.
name: Kim, William Y.
name: Lin, C. Michael
name: Forest, M. Gregory
name: Wobker, Sara E.
name: Lai, Samuel K.
name: Huang, Leaf
Publisher: name: American Chemical Society (ACS)
Year: 2016

description: The binding site barrier (BSB) was originally proposed to describe the binding behavior of antibodies to cells peripheral to blood vessels, preventing their further penetration into the tumors. Yet, it is revisited herein to describe the intratumoral cellular disposition of nanoparticles (NPs). Specifically, the BSB limits NP diffusion and results in unintended internalization of NPs by stroma cells localized near blood vessels. This not only limits the therapeutic outcome but also promotes adverse off-target effects. In the current study, it was shown that tumor-associated fibroblast cells (TAFs) are the major component of the BSB, particularly in tumors with a stroma-vessel architecture where the location of TAFs aligns with blood vessels. Specifically, TAF distance to blood vessels, expression of receptor proteins, and binding affinity affect the intensity of the BSB. The physical barrier elicited by extracellular matrix also prolongs the retention of NPs in the stroma, potentially contributing to the BSB. The influence of particle size on the BSB was also investigated. The strongest BSB effect was found with small (∼18 nm) NPs targeted with the anisamide ligand. The uptake of these NPs by TAFs was about 7-fold higher than that of the other cells 16 h post-intravenous injection. This was because TAFs also expressed the sigma receptor under the influence of TGF-β secreted by the tumor cells. Overall, the current study underscores the importance of BSBs in the delivery of nanotherapeutics and provides a rationale for exploiting BSBs to target TAFs.
title: Tumores de partes blandas , un reto para el radiólogo
Creators: name: Montull Ferrer, Caterina
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Pathology
subject: Neoplasia
subject: Tissue characterisation
subject: MR
subject: Musculoskeletal soft tissue

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Las lesiones de partes blandas representan a menudo un problema en la práctica diaria hospitalaria en RM,
ya que suele ser la última prueba a la que se recurre con objeto a caracterizar la lesión.
A pesar de los avances en imagen,
estas lesiones...
Supplementary document for Fluorescent bacterial biosensor E. coli/pTdcR-TurboYFP sensitive to terahertz radiation - 4941623.pdf
Creators: name: Serdyukov, Danil
name: Goryachkovskaya, Tatiana
name: Mescheryakova, Irina
name: Kuznetsov, Sergei
name: Popik, Vasiliy
name: Peltek, Sergey
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Table S1, figures S1-S3