cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dirac gauginos and unification in F-theory
Creators: name: Davies, Rhys
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Supersymmetric models in which the gauginos acquire Dirac masses, rather than Majorana masses, offer an appealing alternative to the minimal supersymmetric standard model, especially in the light of the bounds set on superpartner masses by the 2011 LHC data. Dirac gauginos require the presence of chiral multiplets in the adjoint representation of the gauge group, and the realisation of such scenarios in F-theory is the subject of this paper. The chiral adjoints drastically alter the usual picture of gauge coupling unification, but this is disturbed anyway in F-theory models with non-trivial hypercharge flux. The interplay between these two factors is explored, and it is found for example that viable F-theory unification can be achieved at around the reduced Planck scale, if there is an extra vector-like pair of singlet leptons with TeV-scale mass. I then discuss the conditions which must be satisfied by the geometry and hypercharge flux of an F-theory model with Dirac gauginos. One nice possibility is for the visible sector to be localised on a K3 surface, and this is discussed in some detail. Finally, I describe how to achieve an unbroken discrete R-symmetry in such compactifications, which is an important ingredient in many models with Dirac gauginos, and write down a simple example which has adjoint chiral multiplets, an appropriate R-symmetry, and allows for viable breaking of SU(5) by hypercharge flux.
description: 25 pages, 4 figures. v2: Minor changes; references added. v3: Section 4 modified and expanded; other minor changes
Equivalence of the Path Integral for Fermions in Cartesian and Spherical Coordinates
Creators: name: Briggs, Andrew
name: Camblong, Horacio E.
name: Ordonez, Carlos R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The path-integral calculation for the free energy of a spin-1/2 Dirac-fermion gas is performed in spherical polar coordinates for a flat spacetime geometry. Its equivalence with the Cartesian-coordinate representation is explicitly established. This evaluation involves a relevant limiting case of the fermionic path integral in a Schwarzschild background, whose near-horizon limit has been shown to be related to black hole thermodynamics.
description: 16 pages
Deficiency of DNAJC19 Leads to Upregulation of Cellular Stress Responses
Creators: name: Wachoski-Dark, Emily Mary Ann
Publisher: name: Cumming School of Medicine
Year: 2023
Subjects: subject: Mitochondria
subject: Cellular stress response
subject: Disease mechanism
subject: Integrated stress response
subject: Unfolded protein response
subject: DCMA
subject: Biology--Cell
subject: Microbiology
subject: FOS: Biological sciences

description: The dilated cardiomyopathy with ataxia syndrome (DCMA) is a rare autosomal recessive mitochondrial disease that results from mutations in the poorly characterized DNAJC19 gene and is frequently associated with premature death in children. DNAJC19 is a component of the TIM23 complex which imports proteins into mitochondria but has also been implicated in cardiolipin maturation. Better understanding of the role of DNAJC19 will provide insight into the mechanism of disease. Since previous work did not identify abnormalities in cardiolipin content within patient cells, I hypothesized that deficiency of DNAJC19 would negatively impact mitochondrial protein homeostasis. To address my hypothesis, I quantified the impact of DNAJC19 deficiency on the proteome of DCMA patient dermal fibroblasts. I identified an increase in mitochondrial fission, confirming previous observations. Pathway analysis predicted an upregulation of eukaryotic translation initiation factor 2 (EIF2) signaling in patient cells, indicating increased cellular stress. I identified significant increases in gene expression for key genes involved in the integrated stress response (ISR) and the mitochondrial unfolded protein response (UPRmt). Activation of these stress responses was not accompanied by increases in apoptosis, potentially indicating that patient cells can mitigate the cellular stress they face. I then tested two potential therapeutics: SS-31, which reduces oxidative stress, and tauroursodeoxycholic acid (TUDCA), which refolds proteins in the cytosol. Both compounds prevented upregulation of the ISR and the UPRmt. In conclusion, I have identified a novel upregulation of two key cellular stress response pathways in DCMA patient fibroblasts. This work also identified TUDCA as a potentially novel treatment for DCMA and supports the classification of DCMA as a disease of mitochondrial proteostasis.
Agricultural Bargaining: Process--Problems--Potentials: Proceedings of the 25th National Bargaining Conference Held at the Diplomat Hotel, Hollywood Beach, Florida, January 15-16, 1981
Creators: name: Agricultural Cooperative Service
name: Agricultural Cooperative Service
Publisher: name: Unknown
Year: 1981
Subjects: subject: Agribusiness
subject: Crop Production/Industries
subject: International Relations/Trade
subject: Livestock Production/Industries
subject: Marketing
subject: FOS: Economics and business

description: Excerpt from the report Preface: These proceedings have been published by Agricultural Cooperative Service, U.S. Department of Agriculture, as a part of its activity of arranging and conducting the 25th National Bargaining Conference at the request of bargaining and marketing cooperatives. The conference was held Jan. 15-16, 1981. Proceedings include speeches delivered at the conference and related information.
Synthesis and Characterization of Novel Piezoelectric Solid Solutions
Creators: name: Rowe, Thomas Michael
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Ferroelectricity
subject: Piezoelectricity
subject: Structure and Property Relationships
subject: Materials Science
subject: Chemistry--Inorganic

description: This thesis presents three studies in the synthesis and characterization of three ferroelectric solid solutions that were hypothesized to be viable replacements for the lead-based industry standard material Pb(Zr,Ti)O3 (PZT), due to both environmental concerns and physical property limitations. The first chapter is an introduction to ferro and piezoelectricity along with the perovskite structure. It also describes how element selection and structural deviation can be utilized to design novel materials with targeted properties. The first research chapter involves the (1-x) Na0.5Bi0.5TiO3 – (x)BaTiO3 (NBT-BT) system doping in group 13 elements onto the B-site in order to improve the ferroelectric properties. The third chapter explores the idea of using a polarization extension to form a Morphotropic Phase Boundary (MPB) between paraelectric and ferroelectric phases through compositional changes. The solid solution (1-x) NaNbO3 – (x)BaZrO3 (NN-BZ) was synthesized, and the electromechanical properties were measured in order to see if there was in increase in the piezoelectric response. Chapter four describes the synthesis of a ferroelectric solid solution that improves on PZT’s Curie temperature. Due to this research, a new solid solution (1-x)Bi(Fe2/8Ti3/8Mg3/8)O3 – (x)PbTiO3 (BFTM-PT) was synthesized, and the electromechanical properties were measured.
Characterizing waste rock using automated quantitative electron microscopy
Creators: name: Blaskovich, Randy J
Publisher: name: University of British Columbia
Year: 2013

description: The leaching of metals from waste rock is directly related to the mineralogical composition of the rock. The overall study objective was to evaluate the application of automated quantitative electron microscopy to weathering waste rock. The value of mineral liberation analysis in optimizing mineral processing operations has been well documented. Application of automated mineralogical techniques, such as the Mineral Liberation Analyzer, to environmental studies is less common with no waste rock characterization studies found that specifically use the Mineral Liberation Analyzer. Mineral Liberation Analyzer methodology limitations and advantages were explored in the context of detection and quantification of primary and secondary metal-associated mineral phases. Mineral Liberation Analyzer application to waste rock weathering studies was assessed using laboratory, field cell, and experimental pile samples which were separated into particle-size fractions. Mineral Liberation Analyzer characterization included bulk modal and metal-associated mineralogy, size distribution, and mineral liberation, association, and exposure or availability (to weathering processes) and mineralogical features useful to an environmental modeller. The Mineral Liberation Analyzer consisted of a FEI Quanta 600 scanning electron microscope equipped with dual Bruker-AXS silicon drift detectors, tungsten filament and proprietary software. The Mineral Liberation Analyzer demonstrated characterization of Antamina mine waste rock which would aid the understanding of weathering processes at this and other sites, such as tailings and heap leach activity. Important mineralogical and elemental features determined were: availability / exposure, particle / grain size and shape, association (such as locking and potential mineral-mineral interactions), quantity and type (such as crystal structure reactivity), fractures and porosity. The scope of this study does not extend to linking lithology to secondary mineralogy. The Mineral Liberation Analyzer, in conjunction with geochemistry, particle surface analysis tools, chemical speciation modeling and diagnostic sequential leach can advance waste rock characterization, to improve mitigation strategies for waste rock drainage.
Scaling behavior in the convection-driven Brazil-nut effect
Creators: name: Hejmady, Prakhyat
name: Bandyopadhyay, Ranjini
name: Sabhapandit, Sanjib
name: Dhar, Abhishek
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The Brazil-nut effect is the phenomenon in which a large intruder particle immersed in a vertically shaken bed of smaller particles rises to the top, even when it is much denser. The usual practice, while describing these experiments, has been to use the dimensionless acceleration Γ=a ω^2/g, where a and ωare respectively the amplitude and the angular frequency of vibration and g is the acceleration due to gravity. Considering a vibrated quasi-two-dimensional bed of mustard seeds, we show here that the peak-to-peak velocity of shaking v= aω, rather than Γ, is the relevant parameter in the regime where boundary-driven granular convection is the main driving mechanism. We find that the rise-time τof an intruder is described by the scaling law τ~ (v-v_c)^{-α}, where v_c is identified as the critical vibration velocity for the onset of convective motion of the mustard seeds. This scaling form holds over a wide range of (a,ω), diameter and density of the intruder.
description: 4 pages, 5 figures + supplementary information
Viste da fuori: le nuove identità urbane di Londra e Milano
Creators: name: Pirola, Maurizio Diego
Publisher: name: Università degli  Studi di Milano
Year: 2011

description: Scheda tesi: Viste da fuori: le nuove identità urbane di Londra e Milano
di Maurizio Diego Pirola
description: Altre Modernità, 2011: NUMERO SPECIALE 9/11/2011
Health outcome measures in an aging population : validity, reliability and interpretability
Creators: name: Macri, Erin M.
Publisher: name: University of British Columbia
Year: 2013

description: In Canada, older adults currently represent a record high proportion of about 15% of the population. Associated with aging is the increased prevalence of multiple morbidity, resulting in widely varied and complex health statuses among our aged. Identifying effective strategies to promote healthy aging and reduce comorbidity hinges on the ability to accurately measure health outcomes. This requires the use of valid and reliable instruments with associated reference statistics to enhance interpretability of test scores. In Chapter 2, I present a validity study of a patient-reported outcome measure, the Patellofemoral Pain and Osteoarthritis Outcome Scale (PFOOS). The PFOOS is designed to evaluate symptoms relating to patellofemoral (PF) pain and osteoarthritis. I recruited 54 adults aged 18+ with peri- or retro-patellar pain for ≥ 3 months, rated ≥3/10 on a numeric pain scale, aggravated by PF-loading tasks (e.g. squats). People with diffuse knee pain, history of total knee or hip replacement, or severe knee trauma in the past year were excluded. Recruitment was done through adverts to staff & students at an Australian University. Participants completed paper & online versions of the PFOOS, Anterior Knee Pain Scale and SF-36, and repeated the PFOOS in 1-2 weeks. Analysis included internal consistency (Cronbach’s α), test-retest & alternate forms reliability (ICC), and construct validation (hypothesis testing). ICCs were ≥ 0.79, Cronbach’s α ≥ 0.61. The PFOOS performed largely as hypothesized. Overall, the PFOOS demonstrated good validity & reliability in this sample. In Chapter 3, I report results of a cross-sectional study aimed to develop normative data for the de Morton Mobility Index (DEMMI). The DEMMI is a performance-based instrument that measures mobility across a spectrum from bed bound to functional independent mobility. A sample of 183 healthy, community-dwelling adults age 60+ were recruited. Mean DEMMI scores varied by age category, by living arrangement (independent vs. assisted living), and by use of mobility aid (p<0.05). Scores did not differ by sex (p=0.49) or falls history (p=0.21). Reference intervals were provided for individual and group comparison, to facilitate use of the DEMMI across the mobility spectrum in clinical and research settings.
A Precocious End of Innocence: Re-reading Children's Literature for Today
Creators: name: Vallorani, Nicoletta
Publisher: name: Università degli  Studi di Milano
Year: 2010

description: A Precocious End of Innocence: Re-reading Children's Literature for Today
(Laura Tosi (ed.), Hearts of Lightness: the Magic of Children's Literature, Venezia, Cafoscarina, 2001, p.197 ISBN88-88613-18-8)
by Nicoletta Vallorani
description: Altre Modernità, No 4 (2010): La morte e i suoi riti nella cultura contemporanea
The decay of Batchelor and Saffman rotating turbulence
Creators: name: Teitelbaum, T.
name: Mininni, P. D.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: The decay rate of isotropic and homogeneous turbulence is known to be affected by the large-scale spectrum of the initial perturbations, associated with at least two cannonical self-preserving solutions of the von Kármán-Howarth equation: the so-called Batchelor and Saffman spectra. The effect of long-range correlations in the decay of anisotropic flows is less clear, and recently it has been proposed that the decay rate of rotating turbulence may be independent of the large-scale spectrum of the initial perturbations. We analyze numerical simulations of freely decaying rotating turbulence with initial energy spectra $\sim k^4$ (Batchelor turbulence) and $\sim k^2$ (Saffman turbulence) and show that, while a self-similar decay cannot be identified for the total energy, the decay is indeed affected by long-range correlations. The decay of two-dimensional and three-dimensional modes follows distinct power laws in each case, which are consistent with predictions derived from the anisotropic von Kármán-Howarth equation, and with conservation of anisotropic integral quantities by the flow evolution.
title: T2 Mapping of Knee Cartilage: Value of Adding a Sequence for Detection of Early Chondromalacia
Creators: name: Teran Pareja, Vanessa
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Education and training
subject: Imaging sequences
subject: Diagnostic procedure
subject: MR-Functional imaging
subject: MR
subject: Musculoskeletal joint

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe chondral composition and morphologic and quantitative MR chondral evaluation. To review T2 mapping as a quantitative MR imaging technique compared to routine morphologic MR...
Electrokinetic Control of Interfacial Instabilities
Creators: name: Nwani, Benedicta Nkenchor
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Viscous fingering
subject: Electrokinetics
subject: Electrohydrodynamics
subject: Electric field
subject: Wettability
subject: Surfactant
subject: Interfacial tension
subject: Computational fluid dynamics
subject: Interfacial instability
subject: Hele-Shaw cell
subject: Numerical modelling
subject: Engineering--Chemical
subject: Engineering--Petroleum

description: Interfacial instabilities have significant impact on the efficiency of various processes that are present in our surroundings. These instabilities occur due to fluid-fluid interfacial perturbations which could be driven electrically, magnetically, via pressure, surface tension, etc. One of the most frequent occurrences of interfacial instabilities is the displacement of a more viscous fluid by a less viscous one which results in an instability known as ‘viscous fingering’. Controlling viscous fingering is challenging since it occurs at the onset of the displacement and affects the overall displacement pattern observed. Nevertheless, researchers have proposed passive and active control methods to address this issue. The objective of this thesis is to extensively explore the use of electric fields for actively controlling viscous fingering in both miscible and immiscible fluid systems. A combination of experimental and numerical techniques are employed to investigate this phenomenon. The first fluid system examined is immiscible, in which the resident fluid is a perfect dielectric fluid with a preferential wetting on the substrate and no notable fluid-fluid and fluid-wall interfacial charges. The second fluid system involves both miscible and conducting fluids with electro-neutral fluid-fluid interface. The immiscible third fluid system has significant interfacial charges between fluids due to added ionic surfactants in the invading brine, leading to preferential substrate wetting. The results of the first study conducted experimentally, indicated that viscous fingering can be effectively controlled even when one of the fluids is completely non-conductive. Regardless of the magnitude of the applied electric field, positive values stabilized the displacement, while negative values destabilized it. For the miscible fluid system, numerical simulations revealed that the effect of positive or negative electric fields on the displacement (de)-stabilization depended on whether the resident fluid experienced a higher or lower electroosmotic flow under the influence of an electric field. The third study’s experimental results revealed that the presence of the combination of electric field and ionic surfactants dramatically altered the system’s behavior, due to the presence of fluid-fluid interfacial charges that induced electro-Marangoni stresses at the interface when acted upon by an external electric field, which ultimately destabilized the displacement in most cases.
Topological Hubbard model and its high-temperature quantum Hall effect
Creators: name: Neupert, Titus
name: Santos, Luiz
name: Ryu, Shinsei
name: Chamon, Claudio
name: Mudry, Christopher
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The quintessential two-dimensional lattice model that describes the competition between the kinetic energy of electrons and their short-range repulsive interactions is the repulsive Hubbard model. We study a time-reversal symmetric variant of the repulsive Hubbard model defined on a planar lattice: Whereas the interaction is unchanged, any fully occupied band supports a quantized spin Hall effect. We show that at 1/2 filling of this band, the ground state develops spontaneously and simultaneously Ising ferromagnetic long-range order and a quantized charge Hall effect when the interaction is sufficiently strong. We ponder on the possible practical applications, beyond metrology, that the quantized charge Hall effect might have if it could be realized at high temperatures and without external magnetic fields in strongly correlated materials.
description: 11 pages, 5 figures
Localized charge bifurcation in the coupled quantum dots
Creators: name: Mantsevich, V. N.
name: Maslova, N. S.
name: Arseyev, P. I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We analyzed theoretically localized charge relaxation in a double quantum dot (QD) system coupled with continuous spectrum states in the presence of localized electrons Coulomb interaction in a single QD. We have found that for a wide range of system parameters charge relaxation occurs through two stable regimes with significantly different relaxation rates. A peculiar time moment exists in the system at which rapid switching between stable regimes takes place. We consider this phenomenon to be applicable for creation of active elements in nano-electronics based on the fast transition effect between two stable states.
description: 7 pages, 4 figures
title: Oncological emergencies : It exists !
Creators: name: Dkhil, Insaf
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Acute
subject: Complications
subject: MR
subject: CT
subject: Oncology
subject: Emergency

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - Illustrating through a serie of exams the radiological semiology of the most common emergencies in the oncology field - Reviewing the items to be included in a standard report in oncology...
Some Fundamental Properties of a Multivariate von Mises Distribution
Creators: name: Mardia, Kanti V.
name: Voss, Jochen
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: In application areas like bioinformatics multivariate distributions on angles are encountered which show significant clustering. One approach to statistical modelling of such situations is to use mixtures of unimodal distributions. In the literature (Mardia et al., 2011), the multivariate von Mises distribution, also known as the multivariate sine distribution, has been suggested for components of such models, but work in the area has been hampered by the fact that no good criteria for the von Mises distribution to be unimodal were available. In this article we study the question about when a multivariate von Mises distribution is unimodal. We give sufficient criteria for this to be the case and show examples of distributions with multiple modes when these criteria are violated. In addition, we propose a method to generate samples from the von Mises distribution in the case of high concentration.
description: fixed a typo in the article title, minor fixes throughout
title: Effectiveness of diffusion tensor imaging in evaluation of spinal cord compression
Creators: name: Khedr, Doaa
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Neoplasia
subject: Diagnostic procedure
subject: MR-Diffusion/Perfusion
subject: MR
subject: Neuroradiology spine

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Spinal cord compression is a common disorder of spinal cord caused by different etiological factors which involve: spinal tumors, intervertebral disk herniation, trauma, spinal malformations, and others. The clinical symptoms of Spinal cord...
Developing a Non-aureus Staphylococcus Intramammary Probiotic as a Preventative Measure for Bovine Mastitis
Creators: name: Vu, Dennis
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Mastitis
subject: Probiotic
subject: Bovine
subject: Non-aureus Staphylococcus
subject: Genetic Manipulation
subject: Transformation
subject: Allelic Replacement
subject: Microbiology
subject: FOS: Biological sciences
subject: Veterinary Science

description: Bovine mastitis is the most common and economically important disease affecting the dairy industry. Intramammary infection (IMI) with Staphylococcus aureus is the leading cause of contagious mastitis. Interestingly, non-aureus staphylococci (NAS) are frequently found in cows with subclinical mastitis, but with a severity less than with S. aureus. Antibiotics are the main method for preventing and treating mastitis. Misuse and overuse of antibiotics have resulted in the emergence of antimicrobial-resistant bacteria, and thus, alternative treatments are required. Bacteriocins, antimicrobial peptides produced by bacteria, are a promising alternative. We hypothesized that by creating a NAS probiotic through genetically engineering a bacteriocin gene cluster into its genome, it will be able to inhibit S. aureus and prevent mastitis. To achieve this, we needed to find a persistent and non-inflammatory NAS strain that can colonize cow mammary glands by using an experimental mammary infusion model. After finding a persistent and non-inflammatory NAS, we will perform a bacteriocin gene cluster knock-in using allelic replacement. Finally, the probiotic will then be characterized through gene expression and killing assays. This thesis aimed to create an alternative treatment to prevent the growth of mastitis pathogens during the dry period. Ultimately, this will lower the usage of antibiotics and give us another preventative tool against mastitis. We identified S. warneri 2993 as the most persistent and non-inflammatory NAS but unfortunately, we were not able to perform our bacteriocin gene knock-in. Instead, we recommend future studies to re-attempt this gene knock-in but with a different bacteriocin gene cluster for an increased likelihood of success. The probiotic will then need testing in ¬in vivo¬ IMI experiments in mice and then in cows following the protocols we have designed.
Marketing and Bargaining Issues: The 26th Annual Agricultural Bargaining Conference Proceedings
Creators: name: Agricultural Cooperative Service
name: Agricultural Cooperative Service
Publisher: name: Unknown
Year: 1983
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Marketing
subject: FOS: Economics and business

description: Excerpts from the Preface: These proceedings have been published by Agricultural Cooperative Service, U.S. Department of Agriculture, as a part of its activity of arranging and conducting the 26th National Bargaining Conference at the request of bargaining and marketing cooperatives. The conference was held January 28-29, 1982. Proceedings include speeches delivered at the conference and related information.
La ricezione mediatica dell’uchod: The Death of Tolstoy di William Nickell
Creators: name: Illarionova, Elizaveta
Publisher: name: Università degli Studi di Milano
Year: 2010
Subjects: The death of Tolstoy, William Nickell, uchod

description: Il libro
Recensiamo il saggio di William Nickell The Death of Tolstoy: Russia on the Eve, Astapovo Station, Cornell University Press, Ithaca - London, 2010.
description: ENTHYMEMA, No 2 (2010)
Investigating the Mediating Fusion Machinery and Biological Role of a Novel Late-Stage Phagocytic Event
Creators: name: Nguyen, Jenny Ai
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Macrophage
subject: Phagosome
subject: Phagolysosome
subject: Membrane fusion
subject: Antigen presentation
subject: Autophagy
subject: Eructophagy
subject: Education--Health
subject: Education--Sciences
subject: Biology--Cell
subject: Biology--Molecular
subject: Immunology
subject: FOS: Clinical medicine
subject: Biochemistry

description: This dissertation investigates eructophagy, a newly discovered process in which macrophages release soluble contents of the phagolysosome (PL) through fusion with the plasma membrane (PM). This study aims to determine the molecular machinery involved in membrane fusion during eructophagy and its role in antigen presentation. Macrophages play a crucial role in combating infections and maintaining homeostasis by phagocytosing invading pathogens and cellular debris into the phagolysosome (PL). It was believed that the contents of the PL that were not employed for antigen presentation were completely digested and recycled as primary building blocks, while indigestible material were stored in lysosomes. Therefore, how macrophages make immunostimulatory molecules, such as nucleic acids, polysaccharides, or lipids, available for immune detection is not well understood. Recently, eructophagy emerged as a novel process that allows macrophages to expel soluble components of the PL into the external environment, potentially serving as a form of intercellular communication to disseminates otherwise unavailable bioactive molecules during inflammation. The molecular machinery underlying membrane fusion during eructophagy has not been elucidated. To address this, we used a lentiviral short hairpin RNA knockdown library of conditionally immortalized monocytes to target genes involved in fusion, fission, and trafficking events to examine their potential role in eructophagy. A novel microscopy-based assay that reports eructophagy events as flashes of fluorescence was used, and it was found that eructophagy is dependent on genes involved in degradative and secretory autophagy. This led to further exploration of the role of autophagosomes in eructophagy. Vesicular blebs protruding from PLs were observed before eructophagy and vanished after resolution. Interfering with autophagosome-PL or autophagosome-PM fusion modulated the incidences of PL-associated blebs, thereby suggesting that these structures are autophagosomes. Immunofluorescence demonstrated that blebs colocalize with markers of the mature autophagosome ATG5 and LC3B. Furthermore, using supernatant transfer and triple cell coculture experiments, we demonstrate that eructophagy is used by macrophages to transfer antigens to vicinal APCs to enhance antigen presentation to T cells. Collectively, this dissertation reveals a novel mechanism of macrophage-mediated antigen transfer and suggests a putative model in which blebs are mature autophagosomes bridging the PL to the PM to facilitate eructophagy.
NLL soft and Coulomb resummation for squark and gluino production at the LHC
Creators: name: Falgari, P.
name: Schwinn, C.
name: Wever, C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present predictions of the total cross sections for pair production of squarks and gluinos at the LHC, including the stop-antistop production process. Our calculation supplements full fixed-order NLO predictions with resummation of threshold logarithms and Coulomb singularities at next-to-leading logarithmic (NLL) accuracy, including bound-state effects. The numerical effect of higher-order Coulomb terms can be as big or larger than that of soft-gluon corrections. For a selection of benchmark points accessible with data from the 2010-2012 LHC runs, resummation leads to an enhancement of the total inclusive squark and gluino production cross section in the 15-30 % range. For individual production processes of gluinos, the corrections can be much larger. The theoretical uncertainty in the prediction of the hard-scattering cross sections is typically reduced to the 10 % level.
description: 45 pages, 16 Figures, LaTex. v2: published version. Grids with numerical results for the NLL cross sections for squark and gluino production at the 7/8 TeV LHC are included in the submission and are also available at http://omnibus.uni-freiburg.de/~cs1010/susy.html
title: Acromioclavicular Joint Injuries: Pictorial Review
Creators: name: Scherer, Matías
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Education
subject: MR
subject: CT
subject: Conventional radiography
subject: Musculoskeletal soft tissue
subject: Musculoskeletal joint
subject: Musculoskeletal bone
subject: Trauma

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe and illustrate the characteristic findings on acromioclavicular joint injury, making a review of specific anatomic structures involved, injury mechanisms and...
Stefano Bartezzaghi, Scrittori giocatori
Creators: name: Rossi, Laura Lucia
Publisher: name: Università degli Studi di Milano
Year: 2010
Subjects: Stefano Bartezzaghi, Italo Calvino, Primo Levi, David Forster Wallace

description: Questo articolo presenta la recensione dell’ultimo libro del semiologo, critico, enigmista Stefano Bartezzaghi dal titolo Scrittori giocatori in cui l’autore propone un itinerario attraverso le opere di alcuni scrittori (tra i quali Primo Levi, Italo Calvino e David Foster Wallace) che detengono un rapporto privilegiato con il gioco nelle sue varie accezioni: il gioco vero e proprio (scrittori scacchisti, enigmisti, tennisti ecc.), il gioco come elemento narrativo, il gioco linguistico e il gioco come paradigma teorico della letteratura. Stefano Bartezzaghi, Scrittori giocatori, Einaudi, Torino, 2010.
description: ENTHYMEMA, No 2 (2010)
Bice Mortara Garavelli, Il parlar figurato. Manualetto di figure retoriche
Creators: name: Tripodi, Carlo
Publisher: name: Università degli Studi di Milano
Year: 2010
Subjects: Bice Mortara Garavelli, retorica, manuale, figure retoriche

description: Recensiamo il libro di Bice Mortara Garavelli, Il parlar figurato. Manualetto di figure retoriche, Laterza, Roma – Bari, 2010.
description: ENTHYMEMA, No 2 (2010)
title: Extra-hepatic collateral supply to hepatocellular carcinoma: what a radiologist should know
Creators: name: Arora, Abhishek
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Liver
subject: Gastrointestinal tract
subject: Interventional vascular
subject: Catheter arteriography
subject: MR
subject: MR-Cholangiography
subject: Chemoembolisation
subject: Embolisation
subject: Neoplasia
subject: Cirrhosis

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To know the prevalence, sources and significance of extrahepatic collateral supply (ECS) in hepatocellular carcinoma (HCC). To identify the signs suggesting ECS on multiphase contrast enhanced CT/MRI and Digital Subtraction Angiography (DSA) . To...
Electron spin relaxation in graphene with random Rashba field: Comparison of D'yakonov-Perel' and Elliott-Yafet--like mechanisms
Creators: name: Zhang, P.
name: Wu, M. W.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Aiming to understand the main spin relaxation mechanism in graphene, we investigate the spin relaxation with random Rashba field induced by both adatoms and substrate, by means of the kinetic spin Bloch equation approach. The charged adatoms on one hand enhance the Rashba spin-orbit coupling locally and on the other hand serve as Coulomb potential scatterers. Both effects contribute to spin relaxation limited by the D'yakonov-Perel' mechanism. In addition, the random Rashba field also causes spin relaxation by spin-flip scattering, manifesting itself as an Elliott-Yafet--like mechanism. Both mechanisms are sensitive to the correlation length of the random Rashba field, which may be affected by the environmental parameters such as electron density and temperature. By fitting and comparing the experiments from the Groningen group [Józsa {\it et al.}, Phys. Rev. B {\bf 80}, 241403(R) (2009)] and Riverside group [Pi {\it et al.}, Phys. Rev. Lett. {\bf 104}, 187201 (2010); Han and Kawakami, {\it ibid.} {\bf 107}, 047207 (2011)] which show either D'yakonov-Perel'-- (with the spin relaxation rate being inversely proportional to the momentum scattering rate) or Elliott-Yafet--like (with the spin relaxation rate being proportional to the momentum scattering rate) properties, we suggest that the D'yakonov-Perel' mechanism dominates the spin relaxation in graphene. The latest experimental finding of a nonmonotonic dependence of spin relaxation time on diffusion coefficient by Jo {\it et al.} [Phys. Rev. B {\bf 84}, 075453 (2011)] is also well reproduced by our model.
description: 13 pages, 9 figures, to be published in New J. Phys
title: «Diagnosis and Identification of Etiology in Hemoptysis: Radiological Findings»
Creators: name: LLANOS GONZALEZ, ANA BELEN
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Arteriovenous malformations
subject: Aneurysms
subject: Diagnostic procedure
subject: CT-High Resolution
subject: CT-Angiography
subject: Thorax
subject: Lung
subject: Emergency

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Hemoptysis is the expectoration of blood from the tracheobronchial tree, for an optimal treatment we must know the origin and etiology. Depending on the amount of blood, hemoptysis could be: sputum with blood (hemoptysis sputum), frank hemoptysis...
Pino Menzio, Nel darsi della pagina. Un'etica della scrittura letteraria
Creators: name: Sotgiu, Antonio
Publisher: name: Università degli Studi di Milano
Year: 2010
Subjects: Etica interna, etica esterna, conoscenza, pietas, orientamento

description: Recensiamo Nel darsi della pagina. Un’etica della scrittura letteraria di Pino Menzio, Libreria Stampatori Torino, Torino, 2010.
description: ENTHYMEMA, No 2 (2010)
title: Secretin-Enhanced MRCP: Where Are We Now?
Creators: name: Zalaquett, Eugenio
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Obstruction / Occlusion
subject: Education
subject: MR-Functional imaging
subject: MR-Cholangiography
subject: MR
subject: Pancreas
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To understand the physiologic role of secretin and its utility in magnetic resonance cholangiopancreatography (S-MRCP). To illustrate procedure details when performing S-MRCP. To review some typical and atypical imaging findings in secretin-enhanced...
Nikolaj I. Nikolaev, La critica non ufficiale al «metodo formale» nella cultura russa degli anni '20
Creators: name: Larocca, Giuseppina
Publisher: name: Università degli Studi di Milano
Year: 2010
Subjects: M. M. Bachtin; Scuola filosofica di Nevel’; critica non ufficiale; formalismo; cultura russa anni ’20

description: Il brano che presentiamo in traduzione è tratto dall’articolo M. M. Bachtin, Nevel’skaja škola filosofii i kul’turnaja istorija ’20-ch gg. (M. M. Bachtin, La scuola filosofica di Nevel’ e la storia culturale degli anni ’20), uscito nella curatela di V. L. Machlin intitolata Bachtinskij sbornik (Moskva 2004). Esso intende ricostruire la storia della critica non ufficiale (e quindi non marxista) al metodo formale nel corso degli anni ’20 attraverso una ricca documentazione bibliografica fra cui spiccano i carteggi, gli articoli e le recensioni pubblicate fra il 1921 e il 1930 da parte di numerosi intellettuali del periodo, come il poeta e critico Vladislav Chodasevič (1886-1939), il teorico simbolista Vjačeslav Ivanov (1866-1949), il poeta Andrej Belyj (1880-1934) e il filosofo Michail Bachtin (1895-1975). A questo composito materiale si aggiungono le testimonianze e i saggi di coloro che invece hanno gravitato attorno agli ambienti formalisti e che poi ne hanno preso le distanze; è questo il caso di Viktor Žirmunskij (1891-1971), dei membri del gruppo della rivista «Hermes» legati all’ermeneutica filosofica di Gustav Špet, e dello studioso Viktor Vinogradov (1894-1970).
description: ENTHYMEMA, No 2 (2010)
Landau-Zener-Stuckelberg Interferometry of a Single Electron Charge Qubit
Creators: name: Stehlik, J.
name: Dovzhenko, Y.
name: Petta, J. R.
name: Johansson, J. R.
name: Nori, F.
name: Lu, H.
name: Gossard, A. C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We perform Landau-Zener-Stuckelberg interferometry on a single electron GaAs charge qubit by repeatedly driving the system through an avoided crossing. We observe coherent destruction of tunneling, where periodic driving with specific amplitudes inhibits current flow. We probe the quantum dot occupation using a charge sensor, observing oscillations in the qubit population resulting from the microwave driving. At a frequency of 9 GHz we observe excitation processes driven by the absorption of up to 17 photons. Simulations of the qubit occupancy are in good agreement with the experimental data.
description: Related papers at http://pettagroup.princeton.edu
Correlated molecular plasmas
Creators: name: Morrison, Jonathan P.
Publisher: name: University of British Columbia
Year: 2013

description: Ultracold neutral plasmas (UNPs) are highly correlated, charged-particle systems studied in standard atomic-molecular optical physics laboratories. Advances in ultracold physics techniques have led to the development of magneto-optical traps that permit the localization of micro-Kelvin temperature atomic samples (10⁸ - 10¹⁰ cm -³ that can be photoionized with a defined excess laser energy. Magneto-optical trapping of molecules proves difficult, and to date, lags in reaching conditions attainable for atoms. Molecules possess additional degrees of freedom where energy can flow during laser trapping and cooling. Alternatively, elastic collisions with inert gases offer another route to low temperatures. Super-sonic expansions of target molecules seeded in a noble gas can reduced the translational temperature to values as low as 0.1 K. Here I report on the formation of a molecular ultracold plasma in a molecular beam of nitric oxide seeded in an inert gas. Our method does not directly form a plasma, but instead, I create a Rydberg gas that spontaneously evolves to a plasma. I have verified the transition to a collective plasma state by applying pulsed-fields to the field-free flight region, and observe a signal that persists well beyond classical field amplitudes required to ionize individual Rydberg states. Electric field screening is a collective effect occurring over a characteristic distance, quantified by the Debye length, λ_D. Molecular ultracold plasmas described here exhibit Debye lengths smaller than the overall size, λ_D<<σ. Plasmas of this nature offer an exotic environment for which to study fundamental phenomena. While plasmas are generally thought of as hot, UNPs exist at low enough temperatures that electrostatic interaction energy between particles is greater than their kinetic energy. At this point, charged particles begin to find themselves in local potential energy minima. Over the entire sample this translates to long-range order, or correlation. It is of great interest for researchers studying UNPs to maximize particle correlation, which requires UNPs to remain very cold, and dense through their lifetime.
title: The differentiation of low- and high-grade gliomas using radiomics and machine learning on [18F]FET PET and T1ce MRI
Creators: name: Donche, Sam
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Pathology
subject: Cancer
subject: Computer Applications-Detection, diagnosis
subject: Biopsy
subject: PET-CT
subject: MR
subject: Oncology
subject: Nuclear medicine
subject: Artificial Intelligence

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Gliomas are the most frequent malignant primary brain tumours in adults and can be classified into low-grade glioma (LGG) and high-grade glioma (HGG). Due to the importance of an accurate and early diagnosis, for which histopathology is the gold...
title: "Iodine Allergy" is a Fake Diagnosis
Creators: name: Nairz, Knud
Publisher: name: European Congress of Radiology
Year: 2019
Subjects: subject: Contrast agent-intravenous
subject: CT
subject: Contrast agents
subject: Drugs / Reactions

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To learn that a real «iodine allergy» would be lethal. To understand that the term «iodine allergy» covers a variety of allergies (contrast agent allergy, allergy against iodine-containing antiseptics, even sea-food allergy). To appreciate that...
Simplicial energy and simplicial harmonic maps
Creators: name: Hass, Joel
name: Scott, Peter
Publisher: name: arXiv
Year: 2012
Subjects: subject: Geometric Topology (math.GT)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 58E20 (Primary) 53C43, 57R35, 57M99 (Secondary)

description: We introduce a combinatorial energy for maps of triangulated surfaces with simplicial metrics and analyze the existence and uniqueness properties of the corresponding harmonic maps. We show that some important applications of smooth harmonic maps can be obtained in this setting.
description: Version 1: 51 pages, 5 figures. Version 2: 52 pages, 6 figures. Several minor corrections, and some slightly modified statements and proofs in light of referee's comments. Version 3: 53 pages, 7 figures. Some further clarification added
Predictive Analysis of Air Pollutants: Harnessing Meteorological Data to Forecast Air Quality Concentrations in Cork, Ireland
Creators: name: Rashidunnabi, Md
Publisher: name: Zenodo
Year: 2025

description: Air quality in urban regions worldwide, including Cork, Ireland, is deteriorating dueto pollutants like nitrogen dioxide (NO2) and particulate matter (PM2.5). These pollutants have significant health and environmental implications. This study leveragesrich datasets spanning three decades, from strategic monitoring sites in Cork and meteorological data from Cork Airport. By utilizing machine learning algorithms such asRandom Forests, XGBoost, and CatBoost, this research aims to elucidate how meteorological factors influence NO2 and PM2.5 concentrations and to forecast their futurelevels. The modeling process addresses challenges like missing data and the influenceof external factors like traffic patterns. Initial investigations have shown promising results, especially with ensemble learning models that combine the strengths of individualalgorithms. Ultimately, this research seeks to provide policymakers and urban plannerswith tools to ensure sustainable and healthy urban environments.Keywords: NO2, PM2.5, air quality, Cork, Ireland, meteorological data, machine learning, Random Forests, XGBoost, CatBoost, predictive analysis, urban pollution.