cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: of The power of support from companion animals for people living with mental health problems: a systematic review and narrative synthesis of the evidence
Creators: name: Brooks, Helen
name: Rushton, Kelly
name: Lovell, Karina
name: Bee, Penny
name: Walker, Lauren
name: Grant, Laura
name: Rogers, Anne
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Qualitative Quality Table. Quality scores related to the included qualitative studies. (DOCX 18Â kb)
Structure-based virtual screening of anti-breast cancer compounds from Artemisia absinthium—insights through molecular docking, pharmacokinetics, and molecular dynamic simulations
Creators: name: Gnanaselvan, Suvathika
name: Yadav, Sangilimuthu Alagar
name: Manoharan, Sowmya Priya
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Breast cancer is the world’s second most frequent malignancy, with a significant mortality and morbidity rate. Nowadays, natural breast cancer medicine has piqued attention as disease-curing agent with low side effects. Herein, the leaf powder of Artemisia absinthium was extracted with ethanol, and GC-MS and LC-MS methods were employed to identify the phytocompounds. Using commercial software SeeSAR-9.2 and StarDrop, identified phytocompounds were docked with estrogen and progesterone breast cancer receptors as they promote breast cancer growth to find the binding affinity of the ligands, drugability, and toxicity. Hormone-mediated breast cancer accounts for about 80% of all cases of breast cancer. Cancer cells proliferate when estrogen and progesterone hormones are attached to these receptors. The molecular docking results demonstrated that 3’,4’,5,7-Tetrahydroxyisoflavanone (THIF) has stronger binding efficacy than standard drugs and other phytocompounds with −28.71 (3 hydrogen bonds) and −24.18 kcal/mol (6 hydrogen bonds) binding energies for estrogen and progesterone receptors, respectively. Pharmacokinetics and toxicity analysis were done to predict the drug-likeness of THIF which results in good drugability and less toxicity. The best fit THIF was subjected to a molecular dynamics simulation analysis by using Gromacs to analyze the conformational changes that occurred during protein-ligand interaction and found that, the structural changes were observed. The results from MD simulation and pharmacokinetic studies suggested that THIF can be expected that in vitro and in vivo research on this compound may lead to the development of a potent anti-breast cancer drug in the future. Communicated by Ramaswamy H. Sarma
Democratic innovations against climate change: the French Citizens’ Convention on Climate
Creators: name: Trettel, Martina
Publisher: name: Eurac Research
Year: 2021

description: On July 6th, 2021 the French senate blocked the possibility of holding a referendum on whether to enshrine the fight against climate change in its Constitution. President Macron promised the referendum would put into effect the proposals developed and advanced by Citizens’ Convention on Climate which launched in October 2019.
title: Επικοινωνία στη μουσική-θεραπεία-παιδεία
title: Προσέγγιση CO.M.P.A.S.S.
titleType: AlternativeTitle
Creators: name: Psaltopoulou, Theodora
name: Zafranas, Nikolaos
name: Kaminis, Ioannis
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΕΠΙΚΟΙΝΩΝΙΑ
ΜΟΥΣΙΚΗ ΕΚΠΑΙΔΕΥΣΗ
ΜΟΥΣΙΚΟΘΕΡΑΠΕΙΑ
ΨΥΧΑΝΑΛΥΤΙΚΗ ΠΡΟΣΕΓΓΙΣΗ
Communication
Music Education
Music Therapy
Psychoanalytic Approach

description: Στην σχέση δασκάλου μαθητή η ποιότητα επικοινωνίας κατέχει μια ιδιαίτερα σημαντική θέση. Στους μαθητές μουσικής συχνά παρατηρείται ένα φαινόμενο «ψυχοσωματικής αντιγραφής» του δασκάλου: η γλώσσα του σώματος, η στάση, η συναισθηματική έκφραση, η γνωστική κατανόηση και γενικότερα η όλη μουσική εκτέλεση του μαθητή μοιάζει με μια «επανεκτύπωση» καλής ή/και κακής ποιότητας του τρόπου που παίζει ο δάσκαλος, καθώς και της γενικότερης σχέσης του με τη μουσική και το όργανό του. Πιθανότατα αυτό συμβαίνει διότι υπάρχει περιορισμένη εκπαίδευση σε θέματα επικοινωνίας στη μουσική παιδαγωγική με αποτέλεσμα ο δάσκαλος να λειτουργεί στο μάθημα σε μιμητική βάση έχοντας ως σημείο αφόρμησης προσωπικές εμπειρίες, συχνά παραγνωρίζοντας τη μοναδικότητα του κάθε μαθητή. Έτσι προκύπτουν ερωτήματα όπως: Ποιός είναι ο μαθητής; Ποια η αλήθεια του;Πως μπορεί να προχωρήσει σε προσωπική ανάπτυξη;
Για τους λόγους αυτούς δημιουργήθηκε μια νέα προσέγγιση Co.M.P.A.S.S: Communication Music Processes Awareness Strategies and Solutions (Psaltopoulou, Zafranas, Kaminis, 2014). Αποτελεί καινοτόμο προσέγγιση, η οποία αναδύθηκε μέσα από σχετική ποιοτική έρευνα, όπου επιχειρείται μεταφορά από ψυχαναλυτικό πλαίσιο σε διδακτικό. Το ψυχαναλυτικό υλικό αφορά στα τέσσερα είδη λόγου κατά Jacques Lacan. Βασικός στόχος της μελέτης ήταν η διερεύνηση και κατηγοριοποίηση στα είδη λεκτικής και μη-λεκτικής επικοινωνίας που χρησιμοποιούνται στην διαδραστική σχέση δασκάλου-μαθητή στο μάθημα πιάνου. Περαιτέρω, διερευνήθηκε η συμβολή της συνειδητότητας της ποιότητας του επικοινωνιακού λόγου στη γνωστική, συναισθηματική και γενικότερη ανάπτυξη της σχέσης του μαθητή με το δάσκαλο, τη μουσική και το όργανο.
Πρόκειται για πρωτοποριακή τομή διεπιστημονικής διασύνδεσης μουσικής παιδαγωγικής, επικοινωνίας, μουσικοθεραπείας και ψυχανάλυσης με ευρύ πεδίο άμεσων εφαρμογών και διεθνούς αναγνώρισης.
PACAP key interactions with PAC1, VPAC1, and VPAC2 identified by molecular dynamics simulations
Creators: name: Meireles, Fernando Augusto T. P.
name: Antunes, Deborah
name: Temerozo, Jairo R.
name: Bou-Habib, Dumith Chequer
name: Caffarena, Ernesto Raul
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Medicine
Neuroscience
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) belongs to the glucagon/secretin family. PACAP interacts with the pituitary adenylate cyclase-activating polypeptide receptor type 1 (PAC1) and vasoactive intestinal peptide receptors 1 and 2 (VPAC1 and VPAC2), exhibiting functions in the immune, endocrine, and nervous systems. This peptide is upregulated in numerous instances of brain injury, acting as a neuroprotective agent. It can also suppress HIV-1 and SARS-CoV-2 viral replication in vitro. This work aimed to identify, in each peptide-receptor system, the most relevant residues for complex stability and interaction energy communication via Molecular Dynamics (MD), Free Energy calculations, and Protein-energy networks, thus revealing in detail the underlying mechanisms of activation of these receptors. Hydrogen bond formation, interaction energies, and computational alanine scanning between PACAP and its receptors showed that His1, Asp3, Arg12, Arg14, and Lys15 are crucial to the peptide’s stability. Furthermore, several PACAP interactions with structurally conserved positions deemed necessary in GPCR B1 activation, including Arg2.60, Lys2.67, and Glu7.42, were significant for the peptide’s stability within the receptors. According to the protein-energy network, the connection between Asp3 of PACAP and the receptors’ conserved Arg2.60 represents a critical energy communication hub in all complexes. Additionally, the ECDs of the receptors were also found to function as energy communication hubs for PACAP. Although the overall binding mode of PACAP in the three receptors was found to be highly conserved, Arg12 and Tyr13 of PACAP were more prominent in complex with PAC1, while Ser2 of PACAP was with VPAC2. The detailed analyses performed in this work pave the way for using PACAP and its receptors as therapeutic targets. Communicated by Ramaswamy H. Sarma
Lokale Produkte in Gastronomie und Hotellerie– Die Reise hat erst begonnen
Creators: name: Corradini, Philipp
Publisher: name: Eurac Research
Year: 2021

description: „Also dieser Bauerntoast schmeckt irgendwie anders. Da ist ja auch Sauerkraut drin!“, höre ich einen deutschen Gast, gemütlich an einem Tisch sitzend, voller Begeisterung ausrufen. „Und der Bauchspeck und Marillensenf. Wow, einfach köstlich!“ Die Glurnser Gastwirtin nähert sich dem Tisch und erklärt: „Ja, ist mal eine andere Variante, diese Zusammensetzung der Zutaten ist bei unseren Kunden eigentlich sehr beliebt. Wobei nicht nur die Zusammensetzung, sondern vor allem die Herkunft der Zutaten das Besondere an unserem Bauerntoast ist. Kennen Sie Laas?“ „Ja, da sind wir vorbeigefahren!“, ruft der 10-jährige Sohn des deutschen Ehepaares aus.
Model Misspecification in ABC: Consequences and Diagnostics
Creators: name: Frazier, David T.
name: Robert, Christian P.
name: Rousseau, Judith
Publisher: name: arXiv
Year: 2017
Subjects: subject: Statistics Theory (math.ST)
subject: General Economics (econ.GN)
subject: Methodology (stat.ME)
subject: FOS: Mathematics
subject: FOS: Economics and business
subject: FOS: Computer and information sciences

description: We analyze the behavior of approximate Bayesian computation (ABC) when the model generating the simulated data differs from the actual data generating process; i.e., when the data simulator in ABC is misspecified. We demonstrate both theoretically and in simple, but practically relevant, examples that when the model is misspecified different versions of ABC can yield substantially different results. Our theoretical results demonstrate that even though the model is misspecified, under regularity conditions, the accept/reject ABC approach concentrates posterior mass on an appropriately defined pseudo-true parameter value. However, under model misspecification the ABC posterior does not yield credible sets with valid frequentist coverage and has non-standard asymptotic behavior. In addition, we examine the theoretical behavior of the popular local regression adjustment to ABC under model misspecification and demonstrate that this approach concentrates posterior mass on a completely different pseudo-true value than accept/reject ABC. Using our theoretical results, we suggest two approaches to diagnose model misspecification in ABC. All theoretical results and diagnostics are illustrated in a simple running example.
MOESM6 of Increase in relative skeletal muscle mass over time and its inverse association with metabolic syndrome development: a 7-year retrospective cohort study
Creators: name: Kim, Gyuri
name: Seung-Eun Lee
name: Jun, Ji
name: Lee, You-Bin
name: Jiyeon Ahn
name: Bae, Ji
name: Sang-Man Jin
name: Hur, Kyu
name: Jee, Jae
name: Moon-Kyu Lee
name: Kim, Jae
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 6: Table S6. Association between continuous variable of change in ASM/BMI index from baseline to year 1 and incidence of metabolic syndrome (Cox model).
Search for pair production of vector-like T and B quarks in single-lepton final states using boosted jet substructure in proton-proton collisions at sqrt(s) = 13 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for pair production of massive vector-like T and B quarks in proton-proton collisions at sqrt(s) = 13 TeV is presented. The data set was collected in 2015 by the CMS experiment at the LHC and corresponds to an integrated luminosity of up to 2.6 inverse femtobarns. The T and B quarks are assumed to decay through three possible channels into a heavy boson (either a W, Z or Higgs boson) and a third generation quark. This search is performed in final states with one charged lepton and several jets, exploiting techniques to identify W or Higgs bosons decaying hadronically with large transverse momenta. No excess over the predicted standard model background is observed. Upper limits at 95% confidence level on the T quark pair production cross section are set that exclude T quark masses below 860 GeV in the singlet, and below 830 GeV in the doublet branching fraction scenario. For other branching fraction combinations with B(tH) + B(bW) >= 0.4, lower limits on the T quark range from 790 to 940 GeV. Limits are also set on pair production of singlet vector-like B quarks, which can be excluded up to a mass of 730 GeV. These limits are among the most stringent to date for vector-like T quarks. The techniques showcased here for understanding highly-boosted final states are important as the sensitivity to new particles is extended to higher masses.
description: Replaced with thet published version. Added the journal reference and DOI. All the figures and tables can be found at http://cms-results.web.cern.ch/cms-results/public-results/publications/B2G-16-024 (CMS Public Pages)
Evaluation of phytochemicals from Thymus serpyllum as potential drug candidates to manage oxidative stress in transition dairy cows
Creators: name: Azhar, Jahanzaib
name: Nadeem, Asif
name: Javed, Maryam
name: Ahmad, Hafiz Ishfaq
name: Hassan, Faiz-ul
name: Shah, Faisal Sheraz
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Dairy cows undergo immense stress and experience autoimmune reactions during the transition period, majorly due to the generation of ROS in the body. So, pharmacological approaches are needed to manage oxidative stress in the transition cows. Recently, the use of phytochemicals as feed additives in cows’ nutrition has gained interest in managing various disease conditions. In the current study, we have evaluated the potential effects of phytochemicals derived from methanolic extract of Thymus serpyllum against oxidative stress and autoimmunity via inhibition of bovine nuclear factor kappa B (NF-κB). The free radical scavenging activity of Thymus serpyllum seed and leaf extracts was 71.8 and 75.6%, respectively at 100 µg/mL concentration. Similarly, both extracts displayed radicals reducing power and inhibition of lipid-peroxidation maximally at 100 µg/mL. A total of 52 bioactive compounds were identified when the plant extract was characterized by the GC-MS analysis, and five (Thymol, Luteolin 7-o-glucuronide, Rosmarinic acid, Apigenin 6,8-di-c-glucoside, Kaempferol) had binding free energy values of −11.6433, −10.002, −8.2615, −7.1714, −6.4870, respectively, in complexes with bovine NF-κB. Through computational analysis, the screened compounds showed good pharmacokinetic parameters, including non-toxicity, non-carcinogenic, high gastrointestinal absorption and thus can serve as potential drug candidates. MD simulation studies predicted the stability of complexes and the complex of Kaempferol was most stable based on RSMD value and MM/GBSA binding energy. The biochemical assays and computational studies indicated that Thymus serpyllum could be used as a promising feed additive in dairy cows to manage oxidative stress during the transition period. Communicated by Ramaswamy H. Sarma
MPEC 2024-U174 : 2024 UM5
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 UM5

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Insieme per sfidare le convenzioni  a colpi di ortaggi
Creators: name: Agosti , Elisa
Publisher: name: Eurac Research
Year: 2021

description: Un viaggio a Cermes equivale ad un biglietto di sola andata nel paese della monocoltura. Dopo aver lasciato il traffico di Bolzano in un pomeriggio di luglio ci ritroviamo circondati da filari di meleti tutti uguali, tutti geometricamente ordinati, molti dei quali coperti da costose reti antigrandine. La spiritualità dei contadini contro il maltempo arriva solo fino ad un certo punto, da lì in poi meglio andare sul sicuro, lasciare le preghiere da parte e affidarsi agli sviluppi tecnologici.
Lettre de Jean-François Séguier à Pierre Joseph Amoreux, 1774-07-25
Creators: name: Séguier, Jean-François
name: Jean-François Séguier
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021

description: [transcription] Je profite, Monsieur, de l’occasion que me fournit Madame votre sœur pour vous envoyer le commentaire de Brisson sur la loi du code théod. où il est parlé des spectacles que vous souhaitez de voir. Je n’ai point le traité de Boulanger dont vous m’avez déjà écrit. On m’a remis les livres que vous m’avez renvoyés. Tous ceux que j’ai sont à votre service. Monsieur Escher est à la foire de Beaucaire. De là, il part pour Zurich sa patrie où il m’a offert ses services. J’ai été fâché que votre voyage n’ait pas eu lieu et que j’aie été privé de vous voir.
Je regrette Monsieur de Soubry. C’était un galant homme fort obligeant et qui m’honorait de son amitié. Nous décampons tous, qui plutôt, qui plus tard. Mon ami Bassi à Bologne en Italie est aussi décédé. Je ne sais si vous connaissez son bel ouvrage sur les bains de Porotta en Italie &c.
Conservez-moi votre amitié et soyez assuré de la continuation de la mienne. Je suis votre bon serviteur.
Séguier
Ce 25e juillet 1774
[fol. 140v] [Du 14 juillet 1774
Monsieur Séguier]
description: [personnes citées] Boulanger, Jules César,…, Escher, Bassi, Jean-André Ignace Soubry (1705-1774), avocat au parlement et trésorier de France au bureau de Lyon.
description: [reférence bibliographique citée] Bassi Ferdinando, Delle Terme Porrettane, Rome, G. Zempel, 1768.
description: Source: ark:/12148/btv1b52508797m
description: Source: [lieu de Conservation] Paris, Bibliothèque nationale de France [cote]NAF 6571, fol. 139
Search for new physics in the monophoton final state in proton-proton collisions at sqrt(s) = 13 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search is conducted for new physics in a final state containing a photon and missing transverse momentum in proton-proton collisions at sqrt(s) = 13 TeV. The data collected by the CMS experiment at the CERN LHC correspond to an integrated luminosity of 12.9 inverse femtobarns. No deviations are observed relative to the predictions of the standard model. The results are interpreted as exclusion limits on the dark matter production cross sections and parameters in models containing extra spatial dimensions. Improved limits are set with respect to previous searches using the monophoton final state. In particular, the limits on the extra dimension model parameters are the most stringent to date in this channel.
description: Replaced with the published version. Added the journal reference and DOI. All the figures and tables can be found at http://cms-results.web.cern.ch/cms-results/public-results/publications/EXO-16-039 (CMS Public Pages)
Glucose regulation by newly synthesized boronic acid functionalized molecules as dipeptidyl peptidase IV inhibitor: a potential compound for therapeutic intervention in hyperglycaemia
Creators: name: Prajapati, Namrata
name: Sharma, Dilip
name: Bidve, Pankaj Ashok
name: Chouhan, Deepak
name: Allani, Meghana
name: Patel, Sagar kumar
name: Chowdhury, Moumita Ghosh
name: Shard, Amit
name: Tiwari, Vinod
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified

description: Management of type 2 diabetes mellitus (T2DM) using dipeptidyl peptidase IV (DPP IV) inhibitors is gaining precedence as this enzyme plays an indispensable role in cleaving and inactivating peptides, such as glucagon-like peptide-1 (GLP-1), incretin hormones, and glucose-dependent insulinotropic polypeptide (GIP). There are several DPP IV inhibitors used to treat T2DM, but limited by side effects such as disturbed GIT, flu-like symptoms, etc. Thus, there is an urgent need for the development of novel and better DPP IV inhibitors for the management of the same. In the present study, we investigated the effect of new boronic acid-based thiazole compounds as DPP IV inhibitors. We used substituted anilines that were progressively modified through a multi-step synthesis and then chemically characterised. These molecules have good binding affinity and molecular interactions at the active site of the DPP IV enzyme. Two boronic acid-based molecules, i.e. PC06R58 and PC06R108, were used for the assessment of their in-vitro enzymatic activities. Both molecules (PC06108 and PC06R58) exhibited potent uncompetitive DPP IV enzyme inhibition at two different concentrations of 90.9 and 15.6 nM, respectively, compared to sitagliptin having an IC50 of 17.3 nM. Furthermore, the oral glucose tolerance test suggested significantly reduced blood glucose levels at 20 mg/kg of the body weight upon administration of PC06R58 and PC06R108 molecules in rats after glucose ingestion (2 g/kg of the body weight). The compounds showed satisfactory DPP IV inhibition. Furthermore, DPP IV inhibitory activity and acceptable pre-ADME/Tox profile indicate it is a lead compound in this novel class of DPP IV inhibitors. Communicated by Ramaswamy H. Sarma
Object-Oriented Software for Functional Data
Creators: name: Happ, Clara
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computation (stat.CO)
subject: FOS: Computer and information sciences

description: This paper introduces the funData R package as an object-oriented implementation of functional data. It implements a unified framework for dense univariate and multivariate functional data on one- and higher dimensional domains as well as for irregular functional data. The aim of this package is to provide a user-friendly, self-contained core toolbox for functional data, including important functionalities for creating, accessing and modifying functional data objects, that can serve as a basis for other packages. The package further contains a full simulation toolbox, which is a useful feature when implementing and testing new methodological developments. Based on the theory of object-oriented data analysis, it is shown why it is natural to implement functional data in an object-oriented manner. The classes and methods provided by funData are illustrated in many examples using two freely available datasets. The MFPCA package, which implements multivariate functional principal component analysis, is presented as an example for an advanced methodological package that uses the funData package as a basis, including a case study with real data. Both packages are publicly available on GitHub and CRAN.
Additional file 1: of What gives rise to clinician gut feeling, its influence on management decisions and its prognostic value for children with RTI in primary care: a prospective cohort study
Creators: name: Turnbull, Sophie
name: Lucas, Patricia
name: Redmond, Niamh
name: Christensen, Hannah
name: Thornton, Hannah
name: Cabral, Christie
name: Blair, Peter
name: Delaney, Brendan
name: Thompson, Matthew
name: Little, Paul
name: Peters, Tim
name: Hay, Alastair
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Web Appendix Table S1. Determinants: univariable associations between sociodemographic, parent-reported symptoms, clinician-reported observations, clinician profile and gut feeling. This table presents the univariable associations between child and clinician variables and gut feeling. (DOCX 21Â kb)
Political communication and vaccination rates: Covid-19 insights from the US
Creators: name: Brooks, Aspen
Publisher: name: Eurac Research
Year: 2021

description: During my studies in Bologna, Italy this school year, Covid-19 was an inescapable presence and topic of conversation. Depending on case levels, we were in and out of lockdowns, as in much of Europe. When vaccines started getting approved and the rollout slowly began, we watched with envy as our friends in the United States started getting vaccinated and returning to a semi-normal life as our weeks in the *zona rossa* stretched on.
title: Πολιτισμικές συνιστώσες της πολιτικής διαδικασίας
Creators: name: Pantelidou Malouta, Maria
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΠΟΛΙΤΙΚΗ ΚΟΥΛΤΟΥΡΑ ΠΟΛΙΤΙΚΗ ΚΟΙΝΩΝΙΚΟΠΟΙΗΣΗ ΠΟΛΙΤΙΚΕΣ ΣΤΑΣΕΙΣ ΑΝΤΙΛΗΨΕΙΣ ΑΞΙΕΣ
ΦΥΛΟ ΕΛΛΗΝΙΚΗ ΠΟΛΙΤΙΚΗ ΚΟΥΛΤΟΥΡΑ
ΓΕΝΙΑ
Socialization
Political Attitudes
Values Political Behaviour Gender
Greek Political Culture Generations

description: Το βιβλίο αυτό στοχεύει στη διερεύνηση του ρόλου των πολιτισμικών παραμέτρων της πολιτικής διαδικασίας. Εξετάζεται η πολιτική κοινωνικοποίηση ως διαδικασία διαμόρφωσης πολιτικών στάσεων, αντιλήψεων και συμπεριφοράς, και ως συνιστώσα της αναπαραγωγής αλλά και της μετεξέλιξης της πολιτικής κουλτούρας μιας κοινωνίας. H προβληματική επικεντρώνεται στην ελληνική κοινωνικο-πολιτική πραγματικότητα, στους ιστορικούς παράγοντες που επέδρασαν στη διαμόρφωση της ελληνικής πολιτικής κουλτούρας, καθώς και στις σύγχρονες εκφράσεις της.

Αρχικά προτείνεται ένα θεωρητικό πλαίσιο ανάλυσης με κριτική παρουσίαση της κλασικής βιβλιογραφίας για τις δύο έννοιες που συνθέτουν το αντικείμενό του, καθώς και για άλλα εννοιολογικά εργαλεία που βρίσκονται στο επίκεντρο κάθε σχετικής προβληματικής, όπως πολιτικές στάσεις, αντιλήψεις και αξίες, πολιτική γενιά, κ.ά. Στη συνέχεια, παρουσιάζεται μια προβληματική για την ελληνική πολιτική κουλτούρα και το ιστορικό της διαμόρφωσης του αντιφατικού και πολυποίκιλου χαρακτήρα της, με κατάληξη στην εξέλιξή της από τη Μεταπολίτευση και μετά και έμφαση στις συνθήκες της κρίσης. Η συζήτηση επικεντρώνεται τόσο σε σταθερές όσο και σε επίκαιρες εκφράσεις της ελληνικής πολιτικής κουλτούρας, με βάση στοιχεία από εμπειρικές έρευνες.

Το τελευταίο μέρος αναφέρεται σε πλευρές της πολιτικής κοινωνικοποίησης και στην εξέλιξη της πολιτικής φυσιογνωμίας των νέων στην Eλλάδα από τη Μεταπολίτευση μέχρι σήμερα, με αναφορές στις ευρύτερες τάσεις εξέλιξης στα αξιακά συστήματα των νέων στην Ευρώπη. Με τη βοήθεια εμπειρικών δεδομένων, διερευνάται η μεταβολή πολιτικών στάσεων και αντιλήψεων, με στόχο την ανάπτυξη προβληματικής σχετικά με τη σύνδεση της πολιτικής κοινωνικοποίησης της νέας γενιάς με την αναπαραγωγή και τη μετεξέλιξη της (ελληνικής) πολιτικής κουλτούρας.

Στο βιβλίο θα υπάρχει Εισαγωγή στο θέμα, καθώς και Συμπεράσματα που θα συνοψίζουν ευρήματα και κεντρικές υποθέσεις, οι απαραίτητοι πίνακες και γραφήματα καθώς και πλούσιος βιβλιογραφικός οδηγός.
Keine Innovation ohne soziale Energie
Creators: name: von Miller, Valeria
Publisher: name: Eurac Research
Year: 2021

description: Die pandemiebedingte Isolation hat uns mürbe gemacht und den Blick auf einen wichtigen Motor unserer Gesellschaft gerichtet: die soziale Energie. Sie ist der Schlüssel für die Entwicklung lebenswerter und nachhaltiger Regionen der Zukunft, sagt Karin Frick, Trend- und Zukunftsforscherin am Schweizer Gottlieb Duttweiler Institut - GDI. Am Freitag, 17. September, spricht sie bei der zweiten Auflage des Futurologischen Kongresses „Energy: The Universal Currency“ in Bozen.
Flavonostilbenes natural hybrids from Rhamnoneuron balansae as potential antitumors targeting ALDH1A1: molecular docking, ADMET, MM-GBSA calculations and molecular dynamics studies
Creators: name: Elsaman, Tilal
name: Ahmad, Iqrar
name: Eltayib, Eyman Mohamed
name: Mohamed, Malik Suliman
name: Yusuf, Osman
name: Saeed, Mohamed
name: Patel, Harun
name: Mohamed, Magdi Awadalla
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Several studies have linked Cancer stem cells (CSCs) to cancer resistance development to chemotherapy and radiotherapy. ALDH1A1 is a key enzyme that regulates the gene expression of CSCs and creates an immunosuppressive tumor microenvironment. It was reported that quercetin and resveratrol were among the inhibitors of ALDH1A1. In early 2022, it was reported that new 11 flavonostilbenes (rhamnoneuronal D–N) were isolated from Rhamnoneuron balansae as potential antiaging natural products. Rhamnoneuronal H (5) could be envisioned as a natural hybrid of quercetin and resveratrol. It was therefore hypothesized that 5 and its analogous isolates rhamnoneuronal D–G (1–4) and rhamnoneuronal I–N (6–11) would have potential ALDH1A1 inhibitory activity. To this end, all isolates were subjected to molecular docking, MM-GBSA, ADMET, and molecular dynamics simulations studies to assess their potential as new leads for cancer treatment targeting ALDH1A1. In silico findings revealed that natural hybrid 5 has a similar binding affinity, judged by MM-GBSA, to the ALDH1A1 active site when compared to the co-crystalized ligand (−64.71 kcal/mole and −64.12 kcal/mole, respectively). Despite having lesser affinity than that of the co-crystalized ligand, the rest of the flavonostilbenes, except 2–4, displayed better binding affinities (−37.55 kcal/mole to −58.6 kcal/mole) in comparison to either resveratrol (−34.44 kcal/mole) or quercetin (−36.48 kcal/mole). Molecular dynamic simulations showed that the natural hybrids 1, 5–11 are of satisfactory stability up to 100 ns. ADMET outcomes indicate that these hybrids displayed acceptable properties and hence could represent an ideal starting point for the development of potent ALDH1A1 inhibitors for cancer treatment. Communicated by Ramaswamy H. Sarma
Actions of Categories by Lipschitz morphisms on limits for the Gromov-Hausdorff Propinquity
Creators: name: Latremoliere, Frederic
Publisher: name: arXiv
Year: 2017
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 46L89, 46L30, 58B34

description: We prove a compactness result for classes of actions of many small categories on quantum compact metric spaces by Lipschitz linear maps, for the topology of the covariant Gromov-Hausdorff propinquity. In particular, our result applies to actions of proper groups by Lipschitz isomorphisms on quantum compact spaces. Our result provides a first example of a structure which passes to the limit of quantum metric spaces for the propinquity, as well as a new method to construct group actions, including from non-locally compact groups seen as inductive limits of compact groups, on unital C*-algebras. We apply our techniques to obtain some properties of closure of certain classes of {\gQqcms s} for the propinquity.
description: 43 pages. Many typos corrected; use category in place of semigroupoids
Additional file 1: of A cross-sectional study assessing the association between online ratings and clinical quality of care measures for US hospitals: results from an observational study
Creators: name: Emmert, Martin
name: Meszmer, Nina
name: Schlesinger, Mark
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Word document. Overview of the applied categorization scheme & Codebook. (DOCX 42 kb)
Wie Bodenverbauung die Landwirtschaft unter Druck setzt
Creators: name: Laner, Peter
Publisher: name: Eurac Research
Year: 2021

description: Südtirols landwirtschaftliche Flächen schrumpfen, weil sie als Bauland verwendet werden. Nachbarländer wie die Schweiz machen vor, wie sie sich schützen lassen.
Higher-order compatible finite element schemes for the nonlinear rotating shallow water equations on the sphere
Creators: name: Shipton, J.
name: Gibson, T. H.
name: Cotter, C. J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We describe a compatible finite element discretisation for the shallow water equations on the rotating sphere, concentrating on integrating consistent upwind stabilisation into the framework. Although the prognostic variables are velocity and layer depth, the discretisation has a diagnostic potential vorticity that satisfies a stable upwinded advection equation through a Taylor-Galerkin scheme; this provides a mechanism for dissipating enstrophy at the gridscale whilst retaining optimal order consistency. We also use upwind discontinuous Galerkin schemes for the transport of layer depth. These transport schemes are incorporated into a semi-implicit formulation that is facilitated by a hybridisation method for solving the resulting mixed Helmholtz equation. We illustrate our discretisation with some standard rotating sphere test problems.
description: accepted version
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 843
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 843, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 843, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 7: Table S2. of Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis
Creators: name: Ruesen, Carolien
name: Lidya Chaidir
name: Laarhoven, Arjan Van
name: Sofiati Dian
name: Ganiem, Ahmad
name: Nebenzahl-Guimaraes, Hanna
name: Huynen, Martijn
name: Bachti Alisjahbana
name: Dutilh, Bas
name: Crevel, Reinout Van
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Ancestral reconstruction of SNP 261869TC in Rv0218. Listed are the internal nodes and leaves where the SNP in Rv0218 occurred according to the ancestral reconstruction of the SNP. (DOCX 72Â kb)
Automatic transversality in contact homology II: filtrations and computations
Creators: name: Nelson, Jo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics

description: This paper is the sequel to the previous paper [Ne15], which showed that sufficient regularity exists to define cylindrical contact homology in dimension three for nondegenerate dynamically separated contact forms, a subclass of dynamically convex contact forms. The Reeb orbits of these so-called dynamically separated contact forms satisfy a uniform growth condition on their Conley-Zehnder indices with respect to a free homotopy class; see Definition 1.7. {Given a contact form which is dynamically separated up to large action, we demonstrate a filtration by action on the chain complex and show how to obtain the desired cylindrical contact homology by taking direct limits.} We give a direct proof of invariance of cylindrical contact homology within the class of dynamically separated contact forms, {and elucidate the independence of the filtered cylindrical contact homology with respect to the choice of the dynamically separated contact form and almost complex structure.} We also show that these regularity results are compatible with geometric methods of computing cylindrical contact homology of prequantization bundles, proving a conjecture of Eliashberg [El07] in dimension three.
description: 76 pages, incorporates changes helpfully suggested by the referee. More details on filtered cylindrical contact homology and the embedded contact homology apparatus used to prove the main regularity results are given
Emocracy: an end or beginning?
Creators: name: Ingruber, Daniela
Publisher: name: Eurac Research
Year: 2021

description: People are too often underestimated, they aren’t a compliant body that succumbs to every emotion and temptation. But, if they are not to withdraw from political coexistence they want and need to be taken seriously. Democracy needs change, constantly and cautiously.
Robust and Accurate Inference via a Mixture of Gaussian and Student's t Errors
Creators: name: Tak, Hyungsuk
name: Ellis, Justin A.
name: Ghosh, Sujit K.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: A Gaussian measurement error assumption, i.e., an assumption that the data are observed up to Gaussian noise, can bias any parameter estimation in the presence of outliers. A heavy tailed error assumption based on Student's t distribution helps reduce the bias. However, it may be less efficient in estimating parameters if the heavy tailed assumption is uniformly applied to all of the data when most of them are normally observed. We propose a mixture error assumption that selectively converts Gaussian errors into Student's t errors according to latent outlier indicators, leveraging the best of the Gaussian and Student's t errors; a parameter estimation can be not only robust but also accurate. Using simulated hospital profiling data and astronomical time series of brightness data, we demonstrate the potential for the proposed mixture error assumption to estimate parameters accurately in the presence of outliers.
Scale-invariant large nonlocality in polycrystalline graphene
Creators: name: Ribeiro, Mário
name: Power, Stephen R.
name: Roche, Stephan
name: Hueso, Luis. E.
name: Casanova, Fèlix
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The observation of large nonlocal resistances near the Dirac point in graphene has been related to a variety of intrinsic Hall effects, where the spin or valley degrees of freedom are controlled by symmetry breaking mechanisms. Engineering strong spin or valley Hall signals on scalable graphene devices could stimulate further practical developments of spin- and valleytronics. Here we report on scale-invariant nonlocal transport in large-scale chemical vapour deposition graphene under an applied external magnetic field. Contrary to previously reported Zeeman spin Hall effect, our results are explained by field-induced spin-filtered edge states whose sensitivity to grain boundaries manifests in the nonlocal resistance. This phenomenon, related to the emergence of the quantum Hall regime, persists up to the millimeter scale, showing that polycrystalline morphology can be imprinted in nonlocal transport. This suggests that topological Hall effects in large-scale graphene materials are highly sensitive to the underlying structural morphology, limiting practical realizations.
description: Main paper (14 pages, 5 figures) and Supplementary information (8 pages, 8 figures)
The creative side of South Tyrol
Creators: name: Psenner, Eleonora
Publisher: name: Eurac Research
Year: 2021

description: The Creative Industries are regarded as one of the key emerging industries in Europe. Networks of creatives urge to pay more attention to underrepresented, remote and rural communities and are mobilizing to foster social participation, innovation, inclusion, accessibility, and cooperation. These values and practices coincide with those we advocate for a sustainable, beautiful and inclusive transformation of our region. Creative hubs have a pivotal role in this process as they are naturally embedded in the local community, future-oriented and embrace a participatory approach.
Molecular dynamics simulations reveal phosphorylation-induced conformational dynamics of the fibroblast growth factor receptor 1 kinase
Creators: name: Mahapatra, Subhasmita
name: Jonniya, Nisha Amarnath
name: Koirala, Suman
name: Kar, Parimal
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: The Fibroblast Growth Factor Receptor1 (FGFR1) kinase wields exquisite control on cell fate, proliferation, differentiation, and homeostasis. An imbalance of FGFR1 signaling leads to several pathogeneses of diseases ranging from multiple cancers to allergic and neurodegenerative disorders. In this study, we investigated the phosphorylation-induced conformational dynamics of FGFR1 in apo and ATP-bound states via all-atom molecular dynamics simulations. All simulations were performed for 2 × 2 µs. We have also investigated the energetics of the binding of ATP to FGFR1 using the molecular mechanics Poisson-Boltzmann scheme. Our study reveals that the FGFR1 kinase can reach a fully active configuration through phosphorylation and ATP binding. A 3–10 helix formation in the activation loop signifies its rearrangement leading to stability upon ATP binding. The interaction of phosphorylated tyrosine (pTyr654) with positively charged residues forms strong salt-bridge interactions, driving the compactness of the structure. The dynamic cross-correlation map reveals phosphorylation enhances correlated motions and reduces anti-correlated motions between different domains. We believe that the mechanistic understanding of large-conformational changes upon the activation of the FGFR1 kinase will aid the development of novel targeted therapeutics. Communicated by Ramaswamy H. Sarma
Extracting a Short Distance Top Mass with Light Grooming
Creators: name: Hoang, Andre H.
name: Mantry, Sonny
name: Pathak, Aditya
name: Stewart, Iain W.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We propose a kinematic method based on a factorization formula for precisely measuring the top quark mass $m_t$ in $pp$ collisions using boosted top jets with light soft drop grooming. By using light grooming, which is an order of magnitude less aggressive than typical grooming, we retain a universal description of the top mass scheme and decay effects, while still effectively removing soft contamination from the top jet. We give field theory results for the hadronization corrections for jets induced by a heavy top quark, showing they are described by a universal hadronic parameter that also appears for groomed light quark jets. An important phenomenological application of our results is that one can obtain $m_t$ in a short distance scheme by fitting the hadron level jet mass distributions, predicted by our factorization formula, to data or by Monte-Carlo calibration. The peaked distributions for $pp$ and $e^+e^-$ collisions are similar, up to sensitivity to underlying event which is significantly reduced by soft drop. Since soft drop implies that the $t$ and $\bar t$ jet masses each can be independently measured, the analysis enables the use of lepton+jet samples.
description: v2: substantially extended text, now has 20 pages with 15 figures
title: 01_2556
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/