cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Polaronic hole-trapping in doped $\rm BaBiO_3$
Creators: name: Franchini, C.
name: Kresse, G.
name: Podloucky, R.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The present {\em ab initio} study shows that in BaBiO$_3$, Bi$^{3+}$ sites can trap two holes from the valence band to form Bi$^{5+}$ cations. The trapping is accompanied by large local lattice distortions, therefore the composite particle consisting of the electronic-hole and the local lattice phonon field forms a polaron. Our study clearly shows that even $sp$ elements can trap carriers at lattice sites, if local lattice relaxations are sufficiently large to screen the localised hole. The derived model describes all relevant experimental results, and settles the issue of why hole doped BaBiO$_3$ remains semiconducting upon moderate hole doping.
description: Physical Review Letters, accepted (2009)
The (Double) White Dwarf Binary SDSS 1257+5428
Creators: name: Kulkarni, S. R.
name: van Kerkwijk, M. H.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: SDSS 1257+5428 is a white dwarf in a close orbit with a companion that has been suggested to be a neutron star. If so, it hosts the closest known neutron star, and its existence implies a great abundance of similar systems and a rate of white-dwarf neutron-star mergers similar to that of the type Ia supernova rate. Here, we present high signal-to-noise spectra of SDSS 1257+5428, which confirm an independent finding that the system is in fact composed of two white dwarfs, one relatively cool and with low mass, and the other hotter and more massive. With this, the demographics and merger rate are no longer puzzling (various factors combine to lower the latter by more than two orders of magnitude). We show that the spectra are fit well with a combination of two hydrogen model atmospheres, as long as the lines of the higher-gravity component are broadened significantly relative to what is expected from just pressure broadening. Interpreting this additional broadening as due to rotation, the inferred spin period is short, about 1 minute. Similarly rapid rotation is only seen in accreting white dwarfs that are magnetic; empirically, it appears that in non-magnetized white dwarfs, accreted angular momentum is lost by nova explosions before it can be transferred to the white dwarf. This suggests that the massive white dwarf in SDSS 1257+5428 is magnetic as well, with B~10^5 G. Alternatively, the broadening seen in the spectral lines could be due to a stronger magnetic field, of ~10^6 G. The two models could be distinguished by further observations.
description: 9 pages, 3 figures, submitted to ApJ
Computational experiment comprehension using provenance summarization
Creators: name: Boufford, Nichole
Publisher: name: University of British Columbia
Year: 2024

description: Scientists often use complex multistep workflows to computationally analyze data. These workflows might include downloading datasets, installing packages, data processing, model training and evaluating the results. It is difficult to effectively manage and track these computational workflows. The fast-paced and iterative nature of research programming leads these workflows to include unused code, multiple versions of the same script, and untracked dependencies. These issues cause difficulties when researchers try to reproduce code that someone else has written, or even code that they have written themselves. Research programmers can address these problems by collecting data provenance: a record of what happened during an experiment, including files touched, execution order, and software dependencies. Provenance provides a record of experiment execution, but provenance graphs are often large and complicated, and quickly become incomprehensible. We propose a new method for summarizing provenance graphs using recent advances in prompting large language models. We use large language model prompting to develop textual summaries of provenance graphs. We perform a user study to compare textual summaries to traditional node-link diagrams for experiment reproduction tasks. Our results show that textual summaries are a promising approach to summarizing provenance for experiment reproduction. We use qualitative results from the user study to motivate future designs for reproducibility tools.
Superconductivity in New Iron Pnictide Oxide (Fe2As2)(Sr4(Mg,Ti)2O6)
Creators: name: Sato, Shinya
name: Ogino, Hiraku
name: Kawaguchi, Naoto
name: Katsura, Yukari
name: Kishio, Kohji
name: Shimoyama, Jun-ichi
name: Kotegawa, Hisashi
name: Tou, Hideki
Publisher: name: arXiv
Year: 2009
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We have discovered a new iron pnictide oxide superconductor (Fe2As2)(Sr4(Mg,Ti)2O6). This material is isostructual with (Fe2As2)(Sr4M2O6) (M = Sc, Cr, V), which were found in previous studies. The structure of this compound is tetragonal with a space group of P4/nmm and consists of the anti-fluorite type FeAs layer and perovskite-type block layer. The lattice constants are a = 3.935 A and c = 15.952 A for (Fe2As2)(Sr4MgTiO6). Bulk superconductivity with Tc(onset) of ~26 K was observed for a partially Co substituted sample. Moreover, Co-free and Ti-rich samples exhibited higher Tc(onset)'s above 35 K, which were further enhanced by applying high pressures up to ~43 K.
description: Resubmission of arXiv:0909.2945 with new data
Clinical characteristics, treatment patterns, disease burden, and persistence/adherence in patients with asthma initiating inhaled triple therapy: real-world evidence from Japan
Creators: name: Suzuki, Takeo
name: Fairburn-Beech, Jolyon
name: Sato, Keiko
name: Kaise, Toshihiko
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: To help optimize triple therapy use, treatment patterns and disease burden were investigated in patients in Japan with persistent asthma who initiated multi-inhaler triple therapy (inhaled corticosteroid/long-acting β2-agonist/long-acting muscarinic antagonist; ICS/LABA/LAMA). This retrospective, observational cohort study using health insurance claims data included adults with persistent asthma who initiated triple therapy in 2016. Patients who were prescribed ICS/LABA in 2016 were included as an ICS/LABA-matched cohort. Patients were stratified into those with asthma only and those with asthma and chronic obstructive pulmonary disease (COPD) codes (asthma-COPD overlap [ACO]). Patient data from 1-year prior to 1 year post index date were analyzed. For patients with asthma only in the triple therapy and ICS/LABA cohorts, baseline demographics were similar. A higher proportion of the triple-therapy cohort than the ICS/LABA cohort was receiving high-dose ICS at index (68.2% and 27.6%, respectively), and had experienced an exacerbation in the last year (64.0% and 29.4%, respectively). The proportion of patients with asthma only who developed any exacerbation was lower in the year following initiation of triple therapy compared with the year prior to initiation of triple therapy (45.8% vs 64.0%, respectively). For asthma only patients receiving triple therapy, the mean (standard deviation) proportion of days covered and medication possession ratio was 0.51 (0.36) and 0.86 (0.16), respectively. Similar trends were seen in patients with ACO in the triple-therapy and ICS/LABA cohorts. Evidence from this study may serve as a reference for the use of inhaled triple therapy for asthma.
Transit timing analysis of the exoplanets TrES-1 and TrES-2
Creators: name: Rabus, M.
name: Deeg, H. J.
name: Alonso, R.
name: Belmonte, J. A.
name: Almenara, J. M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The aim of this work is a detailed analysis of transit light curves from TrES-1 and TrES-2, obtained over a period of three to four years, in order to search for variabilities in observed mid-transit times and to set limits for the presence of additional third bodies. Using the IAC 80cm telescope, we observed transits of TrES-1 and TrES-2 over several years. Based on these new data and previously published work, we studied the observed light curves and searched for variations in the difference between observed and calculated (based on a fixed ephemeris) transit times. To model possible transit timing variations, we used polynomials of different orders, simulated O-C diagrams corresponding to a perturbing third mass and sinusoidal fits. For each model we calculated the chi-squared residuals and the False Alarm Probability (FAP). For TrES-1 we can exclude planetary companions (>1 M_earth) in the 3:2 and 2:1 MMRs having high FAPs based on our transit observations from ground. Additionally, the presence of a light time effect caused by e. g. a 0.09 M_sun mass star at a distance of 7.8 AU is possible. As for TrES-2, we found a better ephemeris of Tc = 2,453,957.63512(28) + 2.4706101(18) x Epoch and a good fit for a sine function with a period of 0.2 days, compatible with a moon around TrES-2 and an amplitude of 57 s, but it was not a uniquely low chi-squared value that would indicate a clear signal. In both cases, TrES-1 and TrES-2, we were able to put upper limits on the presence of additional perturbers masses. We also conclude that any sinusoidal variations that might be indicative of exomoons need to be confirmed with higher statistical significance by further observations, noting that TrES-2 is in the field-of-view of the Kepler Space Telescope.
description: 10 pages; accepted for publication in A&A; replaced abstract
title: Measuring Vulnerabilities in the Non-Financial Corporate Sector Using Industry- and Firm-Level Data
Creators: name: Grieder, Timothy
name: Lipsitz, Michal
Publisher: name: Bank of Canada
Year: 2018

description: Aggregate non-financial corporate debt-to-GDP has been growing rapidly in recent years and is at an all-time high. This growth began in 2011 and accelerated as the oil price shock affected the Canadian economy. In light of these developments, we use industry- and firm-level data to measure vulnerability indicators in the non-financial corporate sector. We find that developments in the oil and mining sectors have had a noticeable impact on aggregate non-financial corporate indebtedness and other vulnerability indicators.
description: Le ratio de la dette des sociétés non financières au PIB a augmenté rapidement ces dernières années et se situe à un sommet historique. Commencée en 2011, la hausse s’est accélérée à mesure que le choc des prix du pétrole faisait ressentir ses effets sur l’économie canadienne. C’est pourquoi nous utilisons des données sectorielles et des données sur les entreprises pour calculer des indicateurs de la vulnérabilité des sociétés non financières. Nous constatons que l’évolution des secteurs pétrolier et minier a eu des effets sensibles sur les indicateurs macroéconomiques de vulnérabilité, notamment ceux de la dette des sociétés non financières.
The solar Julia sets of basic quadratic Cremer polynomials
Creators: name: Blokh, A.
name: Buff, X.
name: Chéritat, A.
name: Oversteegen, L.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Dynamical Systems (math.DS)
subject: General Topology (math.GN)
subject: FOS: Mathematics
subject: 37F10 (Primary), 37B45, 37C25 (Secondary)

description: In general, little is known about the exact topological structure of Julia sets containing a Cremer point. In this paper we show that there exist quadratic Cremer Julia sets of positive area such that for a full Lebesgue measure set of angles the impressions are degenerate, the Julia set is connected im kleinen at the landing points of these rays, and these points are contained in no other impression.
description: 20 pages, 3 figures, to appear in Ergodic Theory and Dynamical Systems
Systematic exploration of the non-geometric flux landscape
Creators: name: AbdusSalam, Shehu
name: Gao, Xin
name: Leontaris, George K.
name: Shukla, Pramod
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Given the huge size of the generic four-dimensional scalar potentials arising from the type II supergravities based on toroidal orientifolds, it is even hard to analytically solve the extremization conditions, and therefore the previous studies have been mainly focused on taking some numerical approaches. In this work, using the so-called {\it axionic flux polynomials} we demonstrate that the scalar potential and the extremization conditions can be simplified to a great extent, leading to the possibility of performing an analytic exploration of the flux landscape. In this regard, we consider the isotropic case of a type IIB model based on the standard ${\mathbb T}^6/({\mathbb Z}_2 \times {\mathbb Z}_2)$ orientifold having the three-form fluxes $F_3/H_3$ and the non-geometric $Q$-flux. This model results in around 300 terms in the scalar potential which depend on 6 moduli/axionic fields and 14 flux parameters. Considering that the axionic flux polynomials can take either zero or non-zero values results in the need of analyzing $2^{14}=16384$ candidate configurations, and we find that more than 16200 of those result in No-Go scenarios for Minkowskian/de-Sitter vacua. Based on our systematic exploration of non-tachyonic flux vacua, we present a detailed classification of such No-Go scenarios as well as the leftover ``undecided" configurations for which we could not conclude about the presence/absence of the stable Minkowskian/de-Sitter vacua.
description: v3: 35 pages, 5 tables, Title changed, minor updates, references added, Published version
Detection of the 158 micron [CII] Transition at z=1.3: Evidence for a Galaxy-Wide Starburst
Creators: name: Hailey-Dunsheath, S.
name: Nikola, T.
name: Stacey, G. J.
name: Oberst, T. E.
name: Parshley, S. C.
name: Benford, D. J.
name: Staguhn, J. G.
name: Tucker, C. E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report the detection of 158 micron [CII] fine-structure line emission from MIPS J142824.0+352619, a hyperluminous (L_IR ~ 10^13 L_sun) starburst galaxy at z=1.3. The line is bright, and corresponds to a fraction L_[CII]/L_FIR = 2 x 10^-3 of the far-IR (FIR) continuum. The [CII], CO, and FIR continuum emission may be modeled as arising from photodissociation regions (PDRs) that have a characteristic gas density of n ~ 10^4.2 cm^-3, and that are illuminated by a far-UV radiation field ~10^3.2 times more intense than the local interstellar radiation field. The mass in these PDRs accounts for approximately half of the molecular gas mass in this galaxy. The L_[CII]/L_FIR ratio is higher than observed in local ULIRGs or in the few high-redshift QSOs detected in [CII], but the L_[CII]/L_FIR and L_CO/L_FIR ratios are similar to the values seen in nearby starburst galaxies. This suggests that MIPS J142824.0+352619 is a scaled-up version of a starburst nucleus, with the burst extended over several kiloparsecs.
description: 6 pages, 3 figures, accepted by ApJ Letters
Evidence for Universal Four-Body States Tied to an Efimov Trimer
Creators: name: Ferlaino, F.
name: Knoop, S.
name: Berninger, M.
name: Harm, W.
name: D'Incao, J. P.
name: Nägerl, H. -C.
name: Grimm, R.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We report on the measurement of four-body recombination rate coefficients in an atomic gas. Our results obtained with an ultracold sample of cesium atoms at negative scattering lengths show a resonant enhancement of losses and provide strong evidence for the existence of a pair of four-body states, which is strictly connected to Efimov trimers via universal relations. Our findings confirm recent theoretical predictions and demonstrate the enrichment of the Efimov scenario when a fourth particle is added to the generic three-body problem.
description: 4 pages, 4 figures
The association between neuraxial anesthesia and the development of childhood asthma – a secondary analysis of the Newborn Epigenetics Study Cohort
Creators: name: Huang, Yueyang
name: Tzeng, Jung-Ying
name: Maguire, Rachel
name: Hoyo, Cathrine
name: Allen, Terrence
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Objectives: Childhood asthma is a common chronic illness that has been associated with mode of delivery. However, the effect of cesarean delivery alone does not fully account for the increased prevalence of childhood asthma. We tested the hypothesis that neuraxial anesthesia used for labor analgesia and cesarean delivery alters the risk of developing childhood asthma. Methods: Within the Newborn Epigenetics Study birth cohort, 196 mother and child pairs with entries in the electronic anesthesia records were included. From these records, data on maternal anesthesia type, duration of exposure, and drugs administered peripartum were abstracted and combined with questionnaire-derived prenatal risk factors and medical records and questionnaire-derived asthma diagnosis data in children. Logistic regression models were used to evaluate associations between type of anesthesia, duration of anesthesia, and the development of asthma in males and females. Results: We found that longer duration of epidural anesthesia was associated with a lower risk of asthma in male children (OR= 0.80; 95% CI =0.66 to 0.95) for each hour of epidural exposure. Additionally, a unit increase in the composite dose of local anesthetics and opioid analgesics administered via the spinal route was associated with a lower risk of asthma in both male (OR= 0.59, 95% CI =0.36 to 0.96) and female children (OR 0.26, 95% CI 0.09 to 0.82). Conclusion: Our data suggest that peripartum exposure to neuraxial anesthesia may reduce the risk of childhood asthma primarily in males. Larger human studies and model systems with longer follow-up are required to elucidate these findings.
Efficacy and safety of coenzyme A versus fenofibrate in patients with hyperlipidemia: a multicenter, double-blind, double-mimic, randomized clinical trial
Creators: name: Chen, Ya-Qin
name: Zhao, Shui-ping
name: Ye, Hui-Jun
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: We investigated the lipid-lowering efficacy and safety of coenzyme A (CoA) versus fenofibrate in Chinese patients with moderate dyslipidemia. A total of 417 subjects (aged 18–75 years) diagnosed with moderate dyslipidemia (triglyceride 2.3–6.5 mmol/L) from 13 large cardiovascular centers in China were recruited and randomly divided into a fenofibrate group (n = 207), which received 200 mg of fenofibrate orally once daily, and a CoA group (n = 210), which received 400 mg of CoA orally once a day. Blood lipoproteins, liver and renal function, creatine kinase, and blood glucose were measured at baseline, and after 4 and 8 weeks of treatment. The baseline triglyceride (TG) level in the fenofibrate group and the CoA group was 3.39 ± 0.99 mmol/L and 3.60 ± 1.11 mmol/L, respectively. After treatment for 4 and 8 weeks with fenofibrate, TG was reduced by 31.62% and 33.13%. In the CoA group, TG was reduced by 17.29% and 23.80%. Compared with baseline, total cholesterol (TC) was significantly decreased in both groups after either 4 or 8 weeks of treatment (p p Compared with fenofibrate, CoA has less effect on reducing plasma TG levels in subjects with moderate dyslipidemia. However, it has fewer adverse effects.
A one-dimensional Vlasov-Maxwell equilibrium for the force-free Harris sheet
Creators: name: Harrison, Michael G.
name: Neukirch, Thomas
Publisher: name: arXiv
Year: 2008
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In this paper the first non-linear force-free Vlasov-Maxwell equilibrium is presented. One component of the equilibrium magnetic field has the same spatial structure as the Harris sheet, but whereas the Harris sheet is kept in force balance by pressure gradients, in the force-free solution presented here force balance is maintained by magnetic shear. Magnetic pressure, plasma pressure and plasma density are constant. The method used to find the equilibrium is based on the analogy of the one-dimensional Vlasov-Maxwell equilibrium problem to the motion of a pseudo-particle in a two-dimensional conservative potential. This potential is equivalent to one of the diagonal components of the plasma pressure tensor. After finding the appropriate functional form for this pressure tensor component, the corresponding distribution functions can be found using a Fourier transform method. The force-free solution can be generalized to a complete family of equilibria that describe the transition between the purely pressure-balanced Harris sheet to the force-free Harris sheet.
description: 10 pages, 2 figures, submitted to PRL, revised version
The cost-effectiveness of radiofrequency ablation for treating patients with gastric antral vascular ectasia refractory to first line endoscopic therapy
Creators: name: Magee, Cormac
name: Graham, David
name: Leonard, Catherine
name: McMaster, Jessica
name: Davies, Heather
name: Skotchko, Maria
name: Lovat, Laurence
name: Murray, Charles
name: Mealing, Stuart
name: Smart, Howard
name: Haidry, Rehan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: This economic evaluation aims to provide a preliminary assessment of the cost-effectiveness of radiofrequency ablation (RFA) compared with argon plasma coagulation (APC) when used to treat APC-refractory gastric antral vascular ectasia (GAVE) in symptomatic patients. A Markov model was constructed to undertake a cost-utility analysis for adults with persistent symptoms secondary to GAVE refractory to first line endoscopic therapy. The economic evaluation was conducted from a UK NHS and personal social services (PSS) perspective, with a 20-year time horizon, comparing RFA with APC. Patients transfer between health states defined by haemoglobin level. The clinical effectiveness data were sourced from expert opinion, resource use and costs were reflective of the UK NHS and benefits were quantified using Quality Adjusted Life Years (QALYs) with utility weights taken from the literature. The primary output was the Incremental Cost-Effectiveness Ratio (ICER), expressed as cost per QALY gained. Over a lifetime time horizon, the base case ICER was £4840 per QALY gained with an 82.2% chance that RFA was cost-effective at a threshold of £20,000 per QALY gained. The model estimated that implementing RFA would result in reductions in the need for intravenous iron, endoscopic intervention and requirement for blood transfusions by 27.1%, 32.3% and 36.5% respectively. Compared to APC, RFA was associated with an estimated 36.7% fewer procedures. RFA treatment is likely to be cost-effective for patients with ongoing symptoms following failure of first line therapy with APC and could lead to substantive reductions in health care resource.
On Fixed Points of Lüders Operation
Creators: name: Weihua, Liu
name: Junde, Wu
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this paper, we prove that if $\mathcal{A}=\{E_i\}_{i=1}^{n}$ is a finite commutative quantum measurement, then the fixed points set of Lüders operation $L_{\cal A}$ is the commutant ${\cal A}'$ of ${\cal A}$, the result answers an open problem partially. We also give a concrete example of a Lüders operation $L_{\cal A}$ with $n=3$ such that $L_{\cal A}(B)=B$ does not imply that the quantum effect $B$ commutes with all $E_1, E_2$ and $E_3$, this example answers another open problem.
58 Radio Sources Near Bright Natural Guide Stars
Creators: name: Stalder, B.
name: Chambers, K. C.
name: Vacca, William D.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a preliminary survey of 58 radio sources within the isoplanatic patches (r < 25") of bright (111) that are now within the capabilities of the current generation of AO-fed integral-field spectrographs. These objects constitute a unique sample that can be used for detailed ground-based AO studies of galactic structure, evolution, and AGN formation at high redshift.
description: 41 pages, 29 figures, accepted to ApJS
Cost-effectiveness of increased screening and treatment of chronic hepatitis C in Korea
Creators: name: Kim, Do Young
name: Wong, Gabriel
name: Lee, Janet
name: Kim, Myung Hwa
name: Smith, Nathaniel
name: Blissett, Rob
name: Kim, Hyung Joon
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Given a hepatitis C virus (HCV) elimination goal by 2030, World Health Organization (WHO) guidelines recommend scaling up HCV screening and treatment with highly-effective direct-acting antivirals (DAAs). This study investigated the cost-effectiveness of various screening and treatment strategies for chronic HCV patients in South Korea in patients aged over 40 as compared to currently screening only high-risk patients. A published Markov disease progression model was used with a screening/treatment decision-tree to model different screening and treatment strategies for Korean HCV patients (aged over 40) from a national payer perspective over a lifetime time horizon. The screening strategies included “screen-all” (upfront only: “once”; or upfront and age 65: “twice”) or a “high-risk only” screening strategy followed by treatment. Treatment strategies included either ledipasvir/sofosbuvir (LDV/SOF), SOF + ribavirin (SOF + RBV; in GT2 only), or glecaprevir/pibrentasvir (GLE/PIB). Model inputs were sourced from published literature and costing databases and validated by Korean hepatologists. Regardless of treatment strategy, a “screen all twice” scenario led to the lowest rates of advanced liver disease events compared to “screen all once” and “high-risk only” screening scenarios. In this screening scenario, treatment with LDV/SOF for GT1/2 dominates (i.e. is more effective and less4costly) LDV/SOF in GT1 and SOF + RBV in GT2, while GLE/PIB is not cost-effective relative to LDV/SOF (₩105,124,920/QALY) at a willingness-to-pay threshold of 1xGDP per capita. Screening all South Korean patients twice followed by LDV/SOF treatment is cost-effective as compared current high-risk screening. Adopting this strategy can help achieve WHO HCV elimination goals.
"BOBURNOMA"GA ZAMONAVIY YONDASHUVLARDA SAIDBEK HASANOVNING O'RNI
Creators: name: Musaev, Islomxon
Publisher: name: Zenodo
Year: 2025

description: XX asr oxiri va XXI asr boshlarida o‘zbek adabiyotshunosligida yangi metodologik qarashlar shakllanib, adabiy matnlarni tahlil qilishda tarixiylik, badiiylik, g‘oyaviy-estetiklik, lingvistik va falsafiy yo‘nalishlar uyg‘unlashdi. Bu jarayonda klassik asarlarni, xususan, Zahiriddin Muhammad Bobur qalamiga mansub “Boburnoma”ni yangicha nuqtayi nazardan tahlil qilishga ehtiyoj sezildi. Ana shunday ilmiy ehtiyojni qondirish yo‘lida fidokorona izlanishlar olib borgan olimlardan biri Saidbek Hasanov bo‘ldi. U “Boburnoma”ni nafaqat tarixiy-biografik manba, balki chuqur falsafiy, badiiy va madaniy fenomen sifatida o‘rgangan ilk zamonaviy tadqiqotchilardan biridir.
Clinical characteristics, treatment patterns, disease burden, and persistence/adherence in patients with asthma initiating inhaled triple therapy: real-world evidence from Japan
Creators: name: Suzuki, Takeo
name: Fairburn-Beech, Jolyon
name: Sato, Keiko
name: Kaise, Toshihiko
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Objectives: To help optimize triple therapy use, treatment patterns and disease burden were investigated in patients in Japan with persistent asthma who initiated multi-inhaler triple therapy (inhaled corticosteroid/long-acting β2-agonist/long-acting muscarinic antagonist; ICS/LABA/LAMA). Methods: This retrospective, observational cohort study using health insurance claims data included adults with persistent asthma who initiated triple therapy in 2016. Patients who were prescribed ICS/LABA in 2016 were included as an ICS/LABA-matched cohort. Patients were stratified into those with asthma only and those with asthma and chronic obstructive pulmonary disease (COPD) codes (asthma-COPD overlap [ACO]). Patient data from 1-year prior to 1-year post index date were analyzed. Results: For patients with asthma only in the triple therapy and ICS/LABA cohorts, baseline demographics were similar. A higher proportion of the triple-therapy cohort than the ICS/LABA cohort was receiving high-dose ICS at index (68.2% and 27.6%, respectively), and had experienced an exacerbation in the last year (64.0% and 29.4%, respectively). The proportion of patients with asthma only who developed any exacerbation was lower in the year following initiation of triple therapy compared with the year prior to initiation of triple therapy (45.8% vs 64.0%, respectively). For asthma only patients receiving triple therapy, the mean (standard deviation) proportion of days covered and medication possession ratio was 0.51 (0.36) and 0.86 (0.16), respectively. Similar trends were seen in patients with ACO in the triple-therapy and ICS/LABA cohorts. Conclusion: Evidence from this study may serve as a reference for the use of inhaled triple therapy for asthma.
Multiple quantum NMR dynamics of spin-1/2 carrying molecules of a gas in nanopores
Creators: name: Doronin, S. I.
name: Fedorova, A. V.
name: Fel'dman, E. B.
name: Zenchuk, A. I.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We consider the multiple quantum (MQ) NMR dynamics of a gas of spin carrying molecules in nanocavities. MQ NMR dynamics is determined by the residual dipole-dipole interactions which are not averaged completely due to the molecular diffusion in nanopores. Since the averaged non-secular Hamiltonian describing MQ NMR dynamics depends on only one coupling constant, this Hamiltonian commutes with the square of the total spin angular momentum $\hat I^2$. We use the basis of common eigenstates of $\hat I^2$ and the projection of $I$ on the external magnetic field for investigation of MQ NMR dynamics. This approach allows us to study MQ NMR dynamics in systems consisting of several hundreds of spins. The analytical approximation of the stationary profile of MQ coherences is obtained. The analytical expressions for MQ NMR coherence intensities of the five-spin system in a nanopore are found. Numerical investigations allow us to find the dependencies of intensities of MQ coherences on their orders (the profiles of MQ coherences) in systems consisting of 600 spins and even more. It is shown that the stationary MQ coherence profile in the considered system is an exponential one.
description: 8 pages, 5 figures
Tetragonal tungsten bronze compounds: relaxor vs mixed ferroelectric - dipole glass behavior
Creators: name: Stephanovich, V. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We demonstrate that recent experimental data (E. Castel et al J.Phys. Cond. Mat. {\bf 21} (2009), 452201) on tungsten bronze compound (TBC) Ba$_2$Pr$_x$Nd$_{1-x}$FeNb$_4$O$_{15}$ can be well explained in our model predicting a crossover from ferroelectric ($x=0$) to orientational (dipole) glass ($x=1$), rather then relaxor, behavior. We show, that since a "classical" perovskite relaxor like Pb(Mn$_{1/3}$ Nb$_{2/3}$)O$_3$ is never a ferroelectric, the presence of ferroelectric hysteresis loops in TBC shows that this substance actually transits from ferroelectric to orientational glass phase with $x$ growth. To describe the above crossover theoretically, we use the simple replica-symmetric solution for disordered Ising model.
description: 5 two-column pages, 4 figures
Efficacy and safety of Coenzyme A versus fenofibrate in patients with hyperlipidemia: a multicenter, double-blind, double-mimic, randomized clinical trial
Creators: name: Chen, Ya-Qin
name: Zhao, Shui-ping
name: Ye, Hui-Jun
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Backgroud: We investigated the lipid-lowering efficacy and safety of coenzyme A (CoA) versus fenofibrate in Chinese patients with moderate dyslipidemia. Methods: A total of 417 subjects (aged 18–75 years) diagnosed with moderate dyslipidemia (triglyceride, 2.3-6.5 mmol/L) from 13 large cardiovascular centers in China were recruited and randomly divided into a fenofibrate group (n = 207), which received 200mg of fenofibrate orally once daily, and a CoA group (n = 210), which received 400mg of CoA orally once a day. Blood lipoproteins, liver and renal function, creatine kinase, and blood glucose were measured at baseline and after 4 and 8 weeks of treatment. Results: The baseline triglyceride (TG) level in the fenofibrate group and the CoA group was 3.39 ± 0.99 mmol/L and 3.60 ± 1.11 mmol/L, respectively. After treatment for 4 and 8 weeks with fenofibrate, TG was reduced by 31.62% and 33.13%. In the CoA group, TG was reduced by 17.29% and 23.80%. Compared with baseline, total cholesterol (TC) was significantly decreased in both groups after either 4 or 8 weeks of treatment (P Conclusions: Compared with fenofibrate, CoA has less effect on reducing plasma TG levels in subjects with moderate dyslipidemia. However, it has fewer adverse effects.
Initial conditions, equations of state and final state in hydrodynamics
Creators: name: Csanad, Mate
Publisher: name: arXiv
Year: 2009
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In this paper we present properties of relativistic and non-relativistic perfect hydrodynamical models. In particular we show illustrations of the fact that different initial conditions and equations of state can lead to the same hadronic final state. This means that alone from the hadronic observables one cannot determine either of the above, one needs for example penetrating probes that inherit their properties from each timeslice of the evolution of the fireball.
description: Presented at the IV Workshop on Particle Correlations and Femtoscopy. 6 pages, 3 figures
Global AdS Picture of 1/2 BPS Wilson Loops
Creators: name: Okuyama, Kazumi
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the holographic dual string configuration of 1/2 BPS circular Wilson loops in N=4 super Yang-Mills theory by using the global coordinate of AdS. The dual string worldsheet is given by the Poincare disk AdS_2 sitting at a constant global time slice of AdS_5. We also analyze the correlator of two concentric circular Wilson loops from the global AdS perspective and study the phase transition associated with the instability of annulus worldsheet connecting the two Wilson loops.
description: 14 pages, 3 figures, v2: discussion on two branches corrected, v3: reference added
SOCIAL PSYCHOLOGICAL FACTORS OF STRESS TOLERANCE OF STUDENTS IN EDUCATIONAL ACTIVITIES
Creators: name: Abdurakhimova Shakhnoza Rakhmonjonovna Andijan State Pedagogical Institute Teacher of the Department of Pedagogy and Psychology
Publisher: name: Zenodo
Year: 2023

description: This article explores the intricate relationship between social psychological factors and stress tolerance among students engaged in educational activities. The study investigates the impact of social support, coping mechanisms, and other relevant factors on the stress levels of students, ultimately influencing their ability to cope with academic challenges. A comprehensive literature analysis, methodological approach, results, and discussion sections contribute to a deeper understanding of the complex interplay between social psychological factors and stress tolerance in the educational context.
Keywords:
 Stress tolerance, students, educational activities, social psychological factors, coping mechanisms, social support, academic performance
Cost-effectiveness of increased screening and treatment of chronic hepatitis C in Korea
Creators: name: Kim, Do Young
name: Wong, Gabriel
name: Lee, Janet
name: Kim, Myung Hwa
name: Smith, Nate
name: Blissett, Rob
name: Kim, Hyung Joon
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Background: Given a hepatitis C virus (HCV) elimination goal by 2030, World Health Organization (WHO) guidelines recommend scaling up HCV screening and treatment with highly-effective direct-acting antivirals (DAAs). This study investigated the cost-effectiveness of various screening and treatment strategies for chronic HCV patients in South Korea in patients aged over 40 as compared to currently screening only high-risk patients. Methods: A published Markov disease progression model was used with a screening/treatment decision-tree to model different screening and treatment strategies for Korean HCV patients (aged over 40) from a national payer perspective over a lifetime time horizon. The screening strategies included ‘screen-all’ (upfront only: ‘once’; or upfront and age 65: ‘twice’) or a ‘high-risk only’ screening strategy followed by treatment. Treatment strategies included either ledipasvir/sofosbuvir (LDV/SOF), SOF + ribavirin (SOF + RBV; in GT2 only), or glecaprevir/pibrentasvir (GLE/PIB). Model inputs were sourced from published literature and costing databases and validated by Korean hepatologists. Results: Regardless of treatment strategy, a ‘screen all twice’ scenario led to the lowest rates of advanced liver disease events compared to ‘screen all once’ and ‘high-risk only’ screening scenarios. In this screening scenario, treatment with LDV/SOF for GT1/2 dominates (i.e., is more effective and less4costly) LDV/SOF in GT1 and SOF + RBV in GT2, while GLE/PIB is not cost-effective relative to LDV/SOF (₩105,124,920/QALY) at a willingness-to-pay threshold of 1xGDP per capita. Conclusion: Screening all South Korean patients twice followed by LDV/SOF treatment is cost-effective as compared current high-risk screening. Adopting this strategy can help achieve WHO HCV elimination goals.
Detection of node group membership in networks with group overlap
Creators: name: Sawardecker, Erin N.
name: Sales-Pardo, Marta
name: Amaral, Luís A. Nunes
Publisher: name: arXiv
Year: 2008
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Most networks found in social and biochemical systems have modular structures. An important question prompted by the modularity of these networks is whether nodes can be said to belong to a single group. If they cannot, we would need to consider the role of "overlapping communities." Despite some efforts in this direction, the problem of detecting overlapping groups remains unsolved because there is neither a formal definition of overlapping community, nor an ensemble of networks with which to test the performance of group detection algorithms when nodes can belong to more than one group. Here, we introduce an ensemble of networks with overlapping groups. We then apply three group identification methods--modularity maximization, k-clique percolation, and modularity-landscape surveying--to these networks. We find that the modularity-landscape surveying method is the only one able to detect heterogeneities in node memberships, and that those heterogeneities are only detectable when the overlap is small. Surprisingly, we find that the k-clique percolation method is unable to detect node membership for the overlapping case.
description: 12 pages, 6 figures. To appear in Euro. Phys. J B
Uncertainty principles for magnetic structures on certain coadjoint orbits
Creators: name: Beltita, Ingrid
name: Beltita, Daniel
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 81S30 (Primary); 22E25, 22E65, 35S05, 47G30 (Secondary)

description: By building on our earlier work, we establish uncertainty principles in terms of Heisenberg inequalities and of the ambiguity functions associated with magnetic structures on certain coadjoint orbits of infinite-dimensional Lie groups. These infinite-dimensional Lie groups are semidirect products of nilpotent Lie groups and invariant function spaces thereon. The recently developed magnetic Weyl calculus is recovered in the special case of function spaces on abelian Lie groups.
description: 19 pages
Fullerenes, Zero-modes, and Self-adjoint Extensions
Creators: name: Roy, Abhishek
name: Stone, Michael
Publisher: name: arXiv
Year: 2009
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We consider the low-energy electronic properties of graphene cones in the presence of a global Fries-Kekulé Peierls distortion. Such cones occur in fullerenes as the geometric response to the disclination associated with pentagon rings. It is well known that the long-range effect of the disclination deficit-angle can be modelled in the continuum Dirac-equation approximation by a spin connection and a non-abelian gauge field. We show here that to understand the bound states localized in the vicinity of a pair of pentagons one must, in addition to the long-range topological effects of the curvature and gauge flux, consider the effect the short-range lattice disruption near the defect. In particular, the radial Dirac equation for the lowest angular-momentum channel sees the defect as a singular endpoint at the origin, and the resulting operator possesses deficiency indices $(2,2)$. The radial equation therefore admits a four-parameter set of self-adjoint boundary conditions. The values of the four parameters depend on how the pentagons are distributed and determine whether or not there are zero modes or other bound states.
description: 20 pages LaTeX, 7 figures
The Two-Loop Hexagon Wilson Loop in N = 4 SYM
Creators: name: Del Duca, Vittorio
name: Duhr, Claude
name: Smirnov, Vladimir A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the planar N=4 supersymmetric Yang-Mills theory, the conformal symmetry constrains multi-loop n-edged Wilson loops to be given in terms of the one-loop n-edged Wilson loop, augmented, for n greater than 6, by a function of conformally invariant cross ratios. That function is termed the remainder function. In a recent paper, we have displayed the first analytic computation of the two-loop six-edged Wilson loop, and thus of the corresponding remainder function. Although the calculation was performed in the quasi-multi-Regge kinematics of a pair along the ladder, the Regge exactness of the six-edged Wilson loop in those kinematics entails that the result is the same as in general kinematics. We show in detail how the most difficult of the integrals is computed, which contribute to the six-edged Wilson loop. Finally, the remainder function is given as a function of uniform transcendental weight four in terms of Goncharov polylogarithms. We consider also some asymptotic values of the remainder function, and the value when all the cross ratios are equal.
description: 120 pages. References added and typos in Appendix G corrected.
Preserved Visual Acuity in Anterior Ischemic Optic Neuropathy Secondary to Giant Cell (temporal) Arteritis
Creators: name: Zeenat Qureshi Stroke Institutes
Publisher: name: Zenodo
Year: 2023

description: Objective—To evaluate the prevalence and clinical profile of patients with biopsy-proven arteritic anterior ischemic optic neuropathy presenting with preserved visual acuity of 20/40 or better and those with an initial poor visual acuity of 20/50 or worse through a retrospective chart review Results—Nine of 37 patients with arteritic anterior ischemic optic neuropathy presented with a preserved visual acuity of 20/40 or better in the affected eye. All patients with preserved visual acuity had initial visual field defects that spared the central field. All 37 patients immediately received high-dose corticosteroid therapy. Visual acuity worsened by > 2 lines in one of nine patients (11%) with preserved visual acuity, with a corresponding progression of visual field constriction. Conclusion—Although preserved visual acuity of 20/40 or better has traditionally been associated with the nonarteritic form of anterior ischemic optic neuropathy, giant cell arteritis should still be strongly considered, especially if they have giant cell arteritis systemic symptoms.