cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MOESM2 of Measles case, immunization coverage and its determinant factors among 12–23 month children, in Bassona Worena Woreda, Amhara Region, Ethiopia, 2018
Creators: name: Ayele Abebe
name: Tamiru Mengistu
name: Abinet Mekuria
Publisher: name: figshare
Year: 2019
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Computational Biology

description: Additional file 2: Table S1. Institutional related factorof respondents, Bassona worena woreda, North Shoa zone, Ethiopia 2017 (n = 575).
title: Martha Washington: A Life
Creators: name: Roy Rosenzweig Center For History And New Media, /
Publisher: name: Roy Rosenzweig Center for History and New Media
Year: 2009
Subjects: subject: Digital history
subject: Women's history
subject: US history
subject: Martha Washington
subject: Mount Vernon

description: The WARC file must be opened using a program like Webrecorder.io. The ZIP contains a static version of the website.
description: A collaborative project with George Washington's Mount Vernon, Martha Washington: A Life is a biography, digital exhibit, and series of lesson plans about the life of the first First Lady of the United States. marthawashington.us
Comment on "Hara's theorem in the constituent quark model"
Creators: name: Zenczykowski, P.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It is pointed out that current conservation alone does not suffice to prove Hara's theorem as it was claimed recently. By explicit calculation we show that the additional implicit assumption made in such "proofs" is that of a sufficiently localized current.
description: 8 pages, Latex
title: Evaluation of the expanded Southampton pilot study (Phase 2) for use of saliva-based lamp testing in asymptomatic populations: Final report, 16th November 2020
Creators: name: Godfrey, Keith
name: Bagust, Lisa
name: Baird, Janis
name: Barker, Mary
name: Batchelor, James
name: Bryant, Sian
name: Colbain, Claire
name: Everest, Helen
name: Flockhart, Andrew
name: Glyn-Owen, Kate Anne
name: Gow, Jessica
name: Hall, Mike
name: Halliday, Barbara
name: Haydon, Melanie
name: Inskip, Hazel
name: Kerr, Katharine
name: Kutty, Harry
name: Johnson, Luke
name: Johnston, Ben
name: Lovelock, Donna
name: Mortimore, Andrew
name: Musgrove, Joanna
name: Olden, Mark
name: Parker, Hayley L.
name: Pearson, Richard
name: Roderick, Paul
name: Sandford, Greg
name: Slater-Jefferies, Joanne
name: Stock, Chris
name: Watson, Daniella
name: Woods-Townsend, Kathryn
name: Ziauddeen, Nida
Publisher: name: University of Southampton
Year: 2020
Subjects: Covid-19
public health

description: This report serves to describe the Southampton Phase 2 saliva testing programme. Separate to formal reporting requirements of the DHSC-funded service evaluation, the aim is for this report to provide a form of manual as guidance for any group that wishes to undertake similar testing.

The report below begins with a general overview of the programme, but then more detailed sections follow relating to: the overall programme; the work in schools; and the work in the University.

Further details are given in the annexes, as follows:

1. Process maps of the entire testing system
2. Instruction leaflet for providing a saliva sample
3. 'Google jam boards' containing the reflections of the teams on their work
4. Communication team overview of the University students and staff experience
5. Newsletters sent to schools each week
6. Post-it notes from pupils at the secondary school giving their views on saliva testing
Primordial Black Holes and the String Swampland
Creators: name: Kawasaki, Masahiro
name: Takhistov, Volodymyr
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The "swampland conjectures" have been recently suggested as a set of criteria to assess if effective field theories (EFTs) are consistent with a quantum gravity embedding. Such criteria, which restrict the behavior of scalar fields in the theory, have strong implications for cosmology in the early universe. As we demonstrate, they will also have direct consequences for formation of primordial black holes (PBHs) and dark matter (DM).
description: 4 pages; v2: minor modifications, added references, published version
Phase Transition in Perovskite Manganites with Orbital Degree of Freedom
Creators: name: Okamoto, S.
name: Ishihara, S.
name: Maekawa, S.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Roles of orbital degree of freedom of Mn ions in phase transition as a function of temperature and hole concentration in perovskite manganites are studied. It is shown that the orbital order-disorder transition is of the first order in the wide region of hole concentration and the N$\rm \acute{e}$el temperature for the anisotropic spin ordering, such as the layer-type antiferromagnetic one, is lower than the orbital ordering temperature due to the anisotropy in the orbital space. The calculated results of the temperature dependence of the spin and orbital order parameters explain a variety of the experiments observed in manganites.
description: 10 pages, 5 figures
title: Newspaper Column: What's in a Name: Smelling the Roses
Creators: name: Nicoson, William J.
Publisher: name: The Connection
Year: 1999

description: PDF file distilled from original WordPerfect document. Original size 11" x 8.5".
description: Juliet Capulet convinced herself that Romeo Montague’s name, hateful to the Capulets, insignificant compared to her love for him. In our later litigious days, her question usually implies that enormous value, rather than insignificance, attaches to a name which someone seeks to borrow. The Herndon Observer, for example, has brought suit against The Fairfax City Observer, claiming that one more Observer in the area is one too many. The Herndon paper has been observing since 1976, while the Fairfax City paper started observing only in 1995.
Inelastic Photoproduction at HERA: a Second Charmonium Crisis?
Creators: name: Eboli, O. J. P.
name: Gregores, E. M.
name: Halzen, F.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The measurement of the inelastic photoproduction of charmonium at HERA seems to have ignited a new charmonium crisis. The (already discredited) color singlet model fits the data for large charmonium energy fraction z, where the NRQCD model qualitatively fails. We here point out that by the straightforward inclusion of color singlet and octet processes in the soft color (color evaporation) scheme, the HERA data can be accommodated for all z. We anticipate that the color singlet model will fail at low z, as it does in hadroproduction.
description: 10 pages, Revtex, uses epsfig.sty to include 4 postscript figures. Also available from the UW-Madison Phenomenology preprint archives at http://pheno.physics.wisc.edu/pub/preprints/1998/madph-98-1045.ps.Z or at ftp://pheno.physics.wisc.edu/pub/preprints/1998/madph-98-1045.ps.Z
Improving DM estimates using low-frequency scattering-broadening estimates
Creators: name: Singha, Jaikhomba
name: Joshi, Bhal Chandra
name: Krishnakumar, M. A.
name: Kareem, Fazal
name: Bathula, Adarsh
name: Dwivedi, Churchil
name: Jacob, Shebin Jose
name: Desai, Shantanu
name: Tarafdar, Pratik
name: Arumugam, P.
name: Arumugam, Swetha
name: Bagchi, Manjari
name: Batra, Neelam Dhanda
name: Dandapat, Subhajit
name: Deb, Debabrata
name: Debnath, Jyotijwal
name: Gopakumar, A
name: Gupta, Yashwant
name: Hisano, Shinnosuke
name: Kato, Ryo
name: Kikunaga, Tomonosuke
name: Marmat, Piyush
name: Nobleson, K.
name: Paladi, Avinash K.
name: B., Arul Pandian
name: Prabu, Thiagaraj
name: Rana, Prerna
name: Srivastava, Aman
name: Surnis, Mayuresh
name: Susobhanan, Abhimanyu
name: Takahashi, Keitaro
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: A pulsar's pulse profile gets broadened at low frequencies due to dispersion along the line of sight or due to multi-path propagation. The dynamic nature of the interstellar medium makes both of these effects time-dependent and introduces slowly varying time delays in the measured times-of-arrival similar to those introduced by passing gravitational waves. In this article, we present an improved method to correct for such delays by obtaining unbiased dispersion measure (DM) measurements by using low-frequency estimates of the scattering parameters. We evaluate this method by comparing the obtained DM estimates with those, where scatter-broadening is ignored using simulated data. A bias is seen in the estimated DMs for simulated data with pulse-broadening with a larger variability for a data set with a variable frequency scaling index, $α$, as compared to that assuming a Kolmogorov turbulence. Application of the proposed method removes this bias robustly for data with band averaged signal-to-noise ratio larger than 100. We report the measurements of the scatter-broadening time and $α$ from analysis of PSR J1643$-$1224, observed with upgraded Giant Metrewave Radio Telescope as part of the Indian Pulsar Timing Array experiment. These scattering parameters were found to vary with epoch and $α$ was different from that expected for Kolmogorov turbulence. Finally, we present the DM time-series after application of this technique to PSR J1643$-$1224.
description: 10 pages, 8 figures, Accepted for publication in MNRAS
Molecular profiling of spontaneous differentiation in a Retinal Pigmented Epithelial cell line
Creators: name: Swann, Carolyn
Publisher: name: Imperial College London
Year: 2023

description: Age-related macular degeneration (AMD) is one of the most common causes of blindness, and results from damage to the macula at the back of the eye. The adult retinal pigmented epithelial-19 (ARPE-19) cell line is currently being used to assist in developing therapies for AMD as these cells display many ‘RPE-like’ characteristics, including a pigmentation-specific gene expression profile similar to that observed in primary human RPE cells. Generation of these differentiated phenotypes require extended periods of culture, but specific culture conditions can result in more rapid cell maturation compared with those in standard culture media. To characterise the molecular events associated with maturation, ARPE-19 cells were cultured in different media (DMEM-based media or X-VIVOTM 10), and serial sampling of cell material and extracellular culture media was conducted over two time-course experiments at regular intervals. Metabolomics (1H quantitative NMR spectroscopy), transcriptomics (RNA-Seq) and proteomics (LC-MS/MS) were used to generate complementary omics data for collected materials. Significant differences between conditions over the experimental culture time course were derived and included in pathway analysis. Visual pigmentation was observed from week three with cells cultured in X-VIVOTM 10 based media compared to those cultured in DMEM-based media. The rate of change of 24 media metabolites by 1H NMR spectroscopy was evaluated and revealed the rate of tyrosine uptake was higher with cells maturing in X-VIVOTM 10 media, consistent with melanogenesis. RNA-Seq analysis showed significant transcriptional changes in the X-VIVOTM 10 cell system including upregulation of key pathways: Wnt and ERK/ MAPK signalling cascade; transcription factor MITF; tyrosine-metabolism pathway genes melanogenic enzymes tyrosinase, tyrosinase-related protein 1, and dopachrome tautomerase. This study provides a novel complementary omic approach in altered melanogenesis/pigmentation pathways associated with ARPE-19 cell maturation and demonstrates the potential use of non-invasive 1H NMR quantitative profiling methods in the monitoring of cell maturation/differentiation in vitro using extracellular media.
Controlled Quasi-Latitudinal Solutions for ultra-fast Spin-Torque Precessional Magnetization Switching
Creators: name: Fortunati, Alessandro
name: d'Aquino, Massimiliano
name: Serpico, Claudio
Publisher: name: arXiv
Year: 2023
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: Primary: 78A25, 34D10, 34H05. Secondary: 37C50, 37C75

description: The aim of the paper is to present a novel class of time-dependent controls to realize ultra-fast magnetization switching in nanomagnets driven by spin-torques produced by spin-polarized electric currents. Magnetization dynamics in such systems is governed by the Landau-Lifshitz-Slonczewski equation which describes the precessional motion of (dimensionless) magnetization vector on the unit-sphere. The relevant case of nanoparticles with uniaxial anisotropy having in-plane easy and intermediate axes and out-of-plane hard axis is considered. By exploiting the characteristic smallness of damping and spin-torque intensity, the aforementioned controls are constructed via suitable perturbative tools in a way to realise approximate \emph{latitudinal solutions} (i.e. motions on a sphere in which the out-of-plane magnetization component stays constant) with the effect to fast ``switch'' the system from one stationary state to another. The possibility to keep a (``small'') bounded value of the out-of-plane coordinate throughout this process of ``transfer'', turns out to be advantageous in the applications as it sensibly reduces the post-switching relaxation oscillations that may cause the failure of switching in real samples. Further relevant quantitative results on the behaviour of the solutions during the pre- and post-switching stages (termed ``expulsion'' and ``attraction'', respectively), are given as a byproduct. A selection of validating numerical experiments is presented alongside the corresponding theoretical results.
description: 28 pages, 7 figures
Role and value of flexibility options in supporting cost-effective power system expansion planning under uncertainties
Creators: name: Borozan, Stefan
Publisher: name: Imperial College London
Year: 2023

description: Decarbonisation actions are driving progressive changes in the technological landscape and operational paradigms in power systems, leading to major challenges and uncertainties. Among else, substantial infrastructure investments are required to accommodate new assets and higher demand, but decision-makers face difficulties as the commitment to flawed investment plans could result in considerable economic, social, and environmental costs. This research aims to address the needs for enhanced coordination, advanced modelling frameworks, and flexible investment options in efforts to manage the risks associated with planning under uncertainties and to facilitate a cost-effective transition to a sustainable future. First, the computational performance of sophisticated modelling frameworks is addressed through the development of a machine learning-enhanced multicut Benders decomposition approach for the stochastic power system expansion planning problem. Its application in the case studies enables the solution of a previously intractable large-scale problem and leads to reductions in average master problem computation times of up to 72%. The focus is then placed on turning the challenge of accommodating future electrical demand of electric vehicles into an opportunity for strategic decision-making by employing smart charging concepts as investment options. For this purpose, the roles and values of Grid-to-Vehicle, Vehicle-to-Grid, and Vehicle-to-Building, in supporting cost-effective expansion planning, are evaluated through novel computationally efficient modelling in a multi-stage stochastic programming framework. Lastly, this research proposes a multi-stage integrated transmission and distribution expansion planning model that co-optimises investments in assets with diverse techno-economic characteristics to investigate the benefits of flexibility options in this context. The role of smart investment alternatives is evaluated with emphasis on investment flexibility as a means to hedge against uncertainties and their value is quantified using insights from Real Options Theory. The case studies validate flexibility options, including smart charging concepts, as viable and highly valuable alternatives to infrastructure reinforcements under all examined conditions.
Unraveling Multifractality and Mobility Edges in Quasiperiodic Aubry-André-Harper Chains through High-Harmonic Generation
Creators: name: Dziurawiec, Marlena
name: de Almeida, Jessica O.
name: Bera, Mohit Lal
name: Płodzień, Marcin
name: Maśka, Maciej M.
name: Lewenstein, Maciej
name: Grass, Tobias
name: Bhattacharya, Utso
Publisher: name: arXiv
Year: 2023
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Quasicrystals are fascinating and important because of their unconventional atomic arrangements, which challenge traditional notions of crystalline structures. Unlike regular crystals, they lack translational symmetry and generate unique mechanical, thermal, and electrical properties, holding promise for numerous applications. In order to probe the electronic properties of quasicrystals, tools beyond linear response transport measurements are needed, since all spectral regions can be affected by the non-periodic geometry. Here we show that high-harmonic spectroscopy offers an advanced avenue for this goal. Focusing on the quasiperiodic 1D Aubry-André-Harper (AAH) model, we leverage high-harmonic spectroscopy to delve into their intricate characteristics: By carefully analyzing emitted harmonic intensities, we extract the multifractal spectrum -- an essential indicator of the spatial distribution of electronic states in quasicrystals. Additionally, we address the detection of mobility edges, vital energy thresholds that demarcate localized and extended eigenstates within generalized AAH models. The precise identification of these mobility edges sheds light on the metal-insulator transition and the behavior of electronic states near these boundaries. Merging high-harmonic spectroscopy with the AAH model provides a powerful framework for understanding the interplay between localization and extended states in quasicrystals for an extremely wide energy range not captured within linear response studies, thereby offering valuable insights for guiding future experimental investigations.
Additional file 1: of Pneumonia in hospitalized neurologic patients: trends in pathogen distribution and antibiotic susceptibility
Creators: name: Lee, Han Sang
name: Jangsup Moon
name: Hye-Rim Shin
name: Ahn, Seon Jae
name: Tae-Joon Kim
name: Jun, Jin-Sun
name: Soon-Tae Lee
name: Keun-Hwa Jung
name: Park, Kyung-Il
name: Jung, Ki-Young
name: Manho Kim
name: Lee, Sang Kun
name: Chu, Kon
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Table S1. Frequency of MDR or non-MDR isolates in HAP cases with or without MDR risk factors. Table S2. Frequency of MDR or non-MDR S. aureus isolates in HAP cases with S. aureus infection. Figure S1. Yearly proportion of isolated pathogens in hospitalized neurologic patients with pneumonia. The ‘Other’ category comprises 30 distinct species. Figure S2. The yearly proportion of pneumonia in hospitalized neurologic patients categorized by the location of the infection. Figure S3. Antibiotic susceptibility of S. aureus in each study period. Figure S4. Antibiotic susceptibility of S. aureus in each study period. Figure S5. Antibiotic susceptibility of S. pneumoniae in the early (n = 6) and late (n = 10) period. (DOCX 538 kb)
Implications of a J^PC exotic
Creators: name: Page, Philip R.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recent experimental data from BNL on the isovector J^PC =1^-+ exotic at 1.6 GeV in ρπindicate the existence of a non-quarkonium state consistent with lattice gauge theory predictions. We discuss how further experiments can strengthen this conclusion. We show that the ρπ, η'πand ηπcouplings of this state qualitatively support the hypothesis that it is a hybrid meson, although other interpretations cannot be eliminated.
description: 10 pages, LaTeX, minor numerical corrections
Synthesis and characterisation of chitosan-coated thermosensitive liposomes for triggered release
Creators: name: Wang, Wenxin
Publisher: name: Imperial College London
Year: 2023

description: Chitosan has been frequently utilized in many areas including drug delivery system, microcapsules, antibacterial agents, blood anti-coagulants and ophthalmology. Most of the liposomes modified by chitosan were used for oral, ocular and pulmonary delivery. Very little research has been undertaken to investigate the effect of chitosan coating on the characterization of liposomes for intravenous injection. HaT (Hyperthermia-Activated Cytotoxic) liposome was selected as the plain liposome formulation in this thesis, which has demonstrated faster release both in vitro and in vivo and superior ability to inhibit tumour growth and lower toxicity to healthy tissues than LTSL (Lysolipid-Containing Thermosensitive Liposome) after intravenous injection followed by hyperthermia. The aim of this thesis is to develop chitosan coated HaT liposomes encapsulated with calcein disodium salt and doxorubicin, respectively and compare their release characteristics with those of plain HaT liposomes. TEM images of plain liposomes and low, medium, and high MW chitaosan coated liposomes (freshly made and stored ones) were compared. Among all three concentrations (0.1%, 0.2% and 0.3% (w/w)), 0.1% (w/w) medium molecular weight chitosan coated HaT liposomes displayed the best overall performance with the lowest increase on both zeta potential and particle size after storage. Therefore, it was selected for the investigations of release property and shelf life of chitosan coated HaT liposomes. The coating of 0.1% (w/w) medium molecular weight chitosan can increase the stability of HaT liposomes encapsulated with calcein disodium salt or doxorubicin at 37 °C and enhance the shelf life of HaT liposomes both at room temperature and at 4 °C after storage. At 40 and 42 °C, the release percentages of chitosan coated liposomes were still substantial with a slight decrease compared to plain HaT liposomes. Finally, several commonly-used pharmaceutical kinetic models were selected to model the release curves of both calcein and doxorubicin encapsulated liposomes.
title: Increase Trust in Finance Section by Using Machine Learning Approach
Creators: name: Muraleedharakumar, Dipukumar
Publisher: name: George Mason University
Year: 2021
Subjects: subject: Finance
subject: Trust
subject: Machine learning
subject: Discrimination

description: In order for the banks to grow, the banks need people, and the people need banks for its money. It's a very simple complex but yet simple relationship. Think of it as one hand washes the other. Institutions such as banks can only become bigger if they are able to profit and capitalize from the interest it gains from its borrowers. To accomplish this goal, it boils down to the bank's ability to provide loans and manage which of its customers are a credit risk. So, in theory, based on the customer's credit score, the banks will determine who is a defaulter or non-defaulter by using it credit scoring analysis.
Imaginary-Temperature Zeros for Quantum Phase Transitions
Creators: name: Liu, Jinghu
name: Yin, Shuai
name: Chen, Li
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: While the zeros of complex partition functions, such as Lee-Yang zeros and Fisher zeros, have been pivotal in characterizing temperature-driven phase transitions, extending this concept to zero temperature remains an open question. In this work, we propose a solution to this issue by calculating the imaginary-temperature zeros (ITZs), which are defined as the roots of the imaginary-temperature partition function. We illustrate the analytical properties of ITZs in the transverse-field Ising chain, showing that the ITZs' distribution can distinguish between various phases and signify the critical exponents. Universal singular behaviors manifest in such quantities as the edge density of ITZs and the magnetization, with the scaling exponents remarkably differing from those in Lee-Yang theory. We further illuminate the consistency between ITZs and the zeros of the spectral form factor, which offers a practical path for the experimental detection of ITZs.
description: 10 pages, 10 figures
Atractylenolide II inhibits tumor-associated macrophages (TAMs)-induced lung cancer cell metastasis
Creators: name: Zhang, Yunting
name: Liu, Yuxi
name: Wang, Jianguang
name: Jiang, Zongying
name: Zhang, Lin
name: Cui, Yong
name: Zhao, Danyu
name: Wang, Yanjie
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: M2-like tumor-associated macrophages (TAMs) play a crucial role in promoting tumor proliferation, angiogenesis, and metastasis. In the current study, we investigated the relationship between macrophage polarization and the antitumor effect of Atractylenolide II (AT-II) in lung cancer cells. Cell viability, migration, and invasion were determined by MTT assay, wound healing assay, and transwell assay, respectively. Flow cytometry analysis showed the percentage of CD206+ cells. Gene expression was determined by real-time PCR, western blotting, and immunofluorescence staining. Lewis lung carcinoma mouse xenograft and metastasis models were used to examine the effects of AT-II on lung cancer in vivo. AT-II (2.5 and 5 µM) did not cause significant inhibition of A549 cell viability but markedly inhibited IL-4/IL-13-induced M2-like polarization, evidenced by the decreased expression of the M2 surface marker CD206, down-regulation of specific M2-marker genes (Arg-1, IL-10 and TGF-β) as well as inhibition of M2 macrophages-mediated invasion and migration of A549 cells. In addition, AT-II inhibited IL-4/IL-13-induced activation of the STAT6 signaling pathway that is vital in the M2-like polarization of macrophages. In animal models, administration of AT-II (50 mg kg−1, i.g., QD for 21 days) significantly inhibited tumor growth, reduced pulmonary metastatic nodules, and down-regulated the percentages of M2 macrophages (F4/80+ and CD206+) in total macrophages (F4/80+) in tumor tissues and pulmonary metastatic nodules. AT-II effectively inhibits M2-like polarization, thereby inhibiting lung cancer cell metastasis both in vivo and in vitro, revealing a novel potential strategy for the antitumor effect of AT-II.
The Greenwood Ledge
Creators: name: (:Null)
Publisher: name: Greenwood, B.C. : G. W. A. Smith
Year: 2016

description: The oldest mining camp newspaper in British Columbia. ; The Ledge was published in Greenwood, in the Kootenay Boundary region of southern British Columbia. The Ledge was published by James W. Grier until 1907, and was subsequently published by R. T. Lowery (1907-1920) and G. W. A. Smith (1920-1929). The paper's longest-serving editor was R. T. Lowery (1906-1926), a prolific newspaper publisher, editor, and printer who was also widely acclaimed for his skill as a writer. The Ledge absorbed the Boundary Creek Times in April 1911, and was published under a variant title, the Greenwood Ledge, from August 1926 to May 1929.
A Measurement of the Branching Ratio of $π^0$ Dalitz Decay using $K_L \rightarrow π^0π^0π^0$ Decays
Creators: name: Abouzaid, E.
name: Arenton, M.
name: Barker, A. R.
name: Bellantoni, L.
name: Blucher, E.
name: Bock, G. J.
name: Cheu, E.
name: Coleman, R.
name: Corcoran, M. D.
name: Cox, B.
name: Erwin, A. R.
name: Escobar, C. O.
name: Glazov, A.
name: Golossanov, A.
name: Gomes, R. A.
name: Gouffon, P.
name: Hsiung, Y. B.
name: Jensen, D. A.
name: Kessler, R.
name: Kotera, K.
name: Ledovskoy, A.
name: McBride, P. L.
name: Monnier, E.
name: Nguyen, H.
name: Niclasen, R.
name: Phillips, D. G.
name: Ramberg, E. J.
name: Ray, R. E.
name: Ronquest, M.
name: Santos, E.
name: Slater, W.
name: Smith, D.
name: Solomey, N.
name: Swallow, E. C.
name: Toale, P. A.
name: Tschirhart, R.
name: Wah, Y. W.
name: Wang, J.
name: White, H. B.
name: Whitmore, J.
name: Wilking, M. J.
name: Winstein, B.
name: Winston, R.
name: Worcester, E. T.
name: Yamanaka, T.
name: Zimmerman, E. D.
name: Zukanovich, R. F.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present a measurement of $B(π^0 \rightarrow e^+e^- γ)/B(π^0 \rightarrow γγ)$, the Dalitz branching ratio, using data taken in 1999 by the E832 KTeV experiment at Fermi National Accelerator Laboratory. We use neutral pions from fully reconstructed $K_L$ decays in flight; the measurement is based on about 60 thousand $K_L \rightarrow π^0π^0π^0 \rightarrow γγ~γγ~e^+e^-γ$ decays. We normalize to $K_L \rightarrow π^0π^0π^0 \rightarrow 6γ$ decays. We find $B(π^0 \rightarrow e^+e^- γ)/B(π^0 \rightarrow γγ)$ $(m_{e^+e^-}$ > 15 MeV/$c^2)$ = $[3.920 \pm 0.016(stat) \pm 0.036 (syst)] \times 10^{-3}$. Using the Mikaelian and Smith prediction for the $e^+e^-$ mass spectrum, we correct the result to the full $e^+e^-$ mass range. The corrected result is $B(π^0 \rightarrow e^+e^- γ)/B(π^0 \rightarrow γγ) = [1.1559 \pm 0.0047(stat) \pm 0.0106 (syst)]$%. This result is consistent with previous measurements and the uncertainty is a factor of three smaller than any previous measurement.
description: 11 pages, 7 figures; v2 accepted version
MOESM1 of Measles case, immunization coverage and its determinant factors among 12â 23Â month children, in Bassona Worena Woreda, Amhara Region, Ethiopia, 2018
Creators: name: Ayele Abebe
name: Tamiru Mengistu
name: Abinet Mekuria
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. English version questionnaire for measles.
Spike-time encoding of gas concentrations using neuromorphic analog sensory front-end
Creators: name: Rastogi, Shavika
name: Dennler, Nik
name: Schmuker, Michael
name: van Schaik, André
Publisher: name: arXiv
Year: 2023
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Gas concentration detection is important for applications such as gas leakage monitoring. Metal Oxide (MOx) sensors show high sensitivities for specific gases, which makes them particularly useful for such monitoring applications. However, how to efficiently sample and further process the sensor responses remains an open question. Here we propose a simple analog circuit design inspired by the spiking output of the mammalian olfactory bulb and by event-based vision sensors. Our circuit encodes the gas concentration in the time difference between the pulses of two separate pathways. We show that in the setting of controlled airflow-embedded gas injections, the time difference between the two generated pulses varies inversely with gas concentration, which is in agreement with the spike timing difference between tufted cells and mitral cells of the mammalian olfactory bulb. Encoding concentration information in analog spike timings may pave the way for rapid and efficient gas detection, and ultimately lead to data- and power-efficient monitoring devices to be deployed in uncontrolled and turbulent environments.
description: \c{opyright} 2023 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works
CXCL12 secreted by pancreatic stellate cells accelerates gemcitabine resistance of pancreatic cancer by enhancing glycolytic reprogramming
Creators: name: Lu, Xiangyu
name: Wu, Yilei
name: Cao, Rui
name: Yu, Xiaojiong
name: Gong, Jun
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Pancreatic stellate cells (PSCs) are the primary cell components of pancreatic cancer (PC) and are involved in tumor growth, metastasis and resistance. However, the role and the mechanism of PSCs in gemcitabine (GEM) resistance to PC still need more investigation. We found that CXCL12 mRNA and secreted CXCL12 protein were higher in PSCs after GEM treatment. The conditioned medium (CM) from GEM-treated PSCs reduced the GEM sensitivity of PC cells. Blocking of CXCL12 in CM by anti-CXCL12 antibody partly restored the GEM sensitivity of PC cells. Blocking of CXCL12 decreased glucose consumption, lactate production, ECAR, and glycolysis-related gene expression in PC cells. The PI3K/AKT/mTOR pathway was activated by the binding of CXCL12 and CXCR4. Moreover, CXCR4 mRNA and protein expressions in PC cells were increased after GEM treatment. Our results indicated the cross-talk between PSCs and PC cells during GEM chemotherapy. CXCL12 secreted by PSCs reduces GEM sensitivity of PC cells by binding to CXCR4 and activating PI3K/AKT/mTOR-glycolysis pathway in PC. Our findings would lay the foundation for solving GEM resistance in PC.
World-Wide Web scaling exponent from Simon's 1955 model
Creators: name: Bornholdt, Stefan
name: Ebel, Holger
Publisher: name: arXiv
Year: 2000
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Recently, statistical properties of the World-Wide Web have attracted considerable attention when self-similar regimes have been observed in the scaling of its link structure. Here we recall a classical model for general scaling phenomena and argue that it offers an explanation for the World-Wide Web's scaling exponent when combined with a recent measurement of internet growth.
description: 1 page RevTeX, no figures
title: Paper: "Information About IASIS and CIM: Frequently Asked Questions, May 1990"
Creators: name: Warfield, John
Publisher: name: George Mason University
Year: 1990
Subjects: subject: Warfield, John N.
subject: Center for Interactive Management (CIM)
subject: Institute for Advanced Study in the Integrative Sciences (IASIS)

description: Manuscript: typescript, 8 pgs., 8.5" x 11" (21.6 cm x 29.7 cm)
description: Provides information on the Institute for Advanced Study in the Integrative Sciences (IASIS) and the Center for Interactive Management (CIM). Also lists where courses, degrees, and seminars relating to IASIS can be found, and describes current or future projects. Last updated January of 1990. John N. Warfield Collection 18.32.2
Transport properties in resonant tunneling heterostructures
Creators: name: Presilla, Carlo
name: Sjöstrand, Johannes
Publisher: name: arXiv
Year: 1996
Subjects: subject: Condensed Matter (cond-mat)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We use an adiabatic approximation in terms of instantaneous resonances to study the steady-state and time-dependent transport properties of interacting electrons in biased resonant tunneling heterostructures. This approach leads, in a natural way, to a transport model of large applicability consisting of reservoirs coupled to regions where the system is described by a nonlinear Schrödinger equation. From the mathematical point of view, this work is non-rigorous but may offer some fresh and interesting problems involving semiclassical approximation, adiabatic theory, non-linear Schrödinger equations and dynamical systems.
description: 25 pages including 9 postscript figures; requires REVTeX 3.0, psfig; uuencoded gz-compressed .tar file; preprint 1133 April 96 Ecole Polytechnique to be published in J. Math. Phys. october 1996
MOESM1 of Selection of the optimal reference genes for expression analyses in different materials of Eriobotrya japonica
Creators: name: Su, Wenbing
name: Yuan, Yuan
name: Zhang, Ling
name: Jiang, Yuanyuan
name: Gan, Xiaoqing
name: Bai, Yunlu
name: Peng, Jiangrong
name: Wu, Jincheng
name: Liu, Yuexue
name: Lin, Shunquan
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Samples used for reference gene selection. Table S2. Primer sequences for reference gene isolation. Figure S1. Melt curve analysis of the selected 11 candidate reference genes. 23 distinct tissues of loquat were tested to show single peak for each primer pair at a specific annealing temperature.
NIHAO XX: The impact of the star formation threshold on the cusp-core transformation of cold dark matter haloes
Creators: name: Dutton, Aaron A.
name: Macciò, Andrea V.
name: Buck, Tobias
name: Dixon, Keri L.
name: Blank, Marvin
name: Obreja, Aura
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We use cosmological hydrodynamical galaxy formation simulations from the NIHAO project to investigate the impact of the threshold for star formation on the response of the dark matter (DM) halo to baryonic processes. The fiducial NIHAO threshold, $n=10\, {\rm cm}^{-3}$, results in strong expansion of the DM halo in galaxies with stellar masses in the range $10^{7.5} < M_{star} < 10^{9.5} M_{\odot}$. We find that lower thresholds such as $n=0.1$ (as employed by the EAGLE/APOSTLE and Illustris/AURIGA projects) do not result in significant halo expansion at any mass scale. Halo expansion driven by supernova feedback requires significant fluctuations in the local gas fraction on sub-dynamical times (i.e., < 50 Myr at galaxy half-light radii), which are themselves caused by variability in the star formation rate. At one per cent of the virial radius, simulations with $n=10$ have gas fractions of $\simeq 0.2$ and variations of $\simeq 0.1$, while $n=0.1$ simulations have order of magnitude lower gas fractions and hence do not expand the halo. The observed DM circular velocities of nearby dwarf galaxies are inconsistent with CDM simulations with $n=0.1$ and $n=1$, but in reasonable agreement with $n=10$. Star formation rates are more variable for higher $n$, lower galaxy masses, and when star formation is measured on shorter time scales. For example, simulations with $n=10$ have up to 0.4 dex higher scatter in specific star formation rates than simulations with $n=0.1$. Thus observationally constraining the sub-grid model for star formation, and hence the nature of DM, should be possible in the near future.
description: 18 pages, 13 figures, accepted to MNRAS
title: Numerical analysis on the sublimation of low-temperature ablator models undergoing shape change in a supersonic wind-tunnel
Creators: name: BIANCHI, Daniele
Publisher: name: Proceedings of the 8th European Conference for Aeronautics and Space Sciences. Madrid, Spain, 1-4 july 2019
Year: 2019
Subjects: HYPERSONICS
CFD
MODELLING
WIND TUNNEL
MATERIALS

description: Ground testing of ablative materials aims at providing critical data on the material behaviour under relevant conditions for the mission. This is normally done in plasma wind tunnel facilities (i.e., ICP torches, arcjets) although the flow velocity is far from being in the hypersonic regime typical of the actual flight. Hence, in order to perform ablative tests with relevant shape change in a hypersonic facility, non-negligible technical challenges have to be faced. To overcome the limitation induced by the reduced total temperature of hypersonic wind tunnels, low-temperature ablators can be used. There is, in fact, a small number of readily available substances that sublimate or ablate in a fashion that can be described fairly accurately by theory at temperatures low enough to make them convenient for use at reasonable supersonic Mach numbers in continuous wind tunnels. Here, a numerical procedure based on CFD analysis to support the definition of the hypersonic capsule shape for the subsequent hypersonic/transonic capsule stability test campaign is presented. The first part of the paper is dedicated to a sensitivity analysis to support the capsule final shape and size selection for experimental testing in VKI facilities. Then, a description of the gas-surface-interaction models implemented into the CFD code for low-temperature ablators thermal response with a discussion of the relevant surface reaction thermodynamics and kinetics is presented. The second part is dedicated to the testing of low-temperature ablators models and their validation including coupled shape-change simulations with mesh evolution and a numerical rebuilding of an experimental test performed in a hypersonic wind tunnel with a camphor model.
Anthoceros agrestis Paton
Creators: name: Rimac, Anja
name: Šegota, Vedran
name: Alegro, Antun
name: Koletić, Nikola
name: Vuković, Nina
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Plantae
Anthocerotophyta
Anthocerotopsida
Anthocerotales
Anthocerotaceae
Anthoceros
Anthoceros agrestis

description: Anthoceros agrestis Paton
 SPECIMEN EXAMINED. — Croatia. Nebojan Village, open ground in a hazelnut plantation, 45.4818°N, 16.1976°E, 190 m a.s.l., 20.IV.2013, leg. Rimac A., det. Rimac A. & Šegota V., ZA[ZA49732]; Ibidem, open ground on the lawn in a yard, 45.4959°N, 16.2038°E, 176 m a.s.l., 7.VIII.2018, leg. Rimac A., det. Rimac A. & Šegota V., ZA[ZA49733]
description: Published as part of Rimac, Anja, Šegota, Vedran, Alegro, Antun, Koletić, Nikola & Vuković, Nina, 2019, Novelties in the hornwort flora of Croatia and Southeast Europe, pp. 289-295 in Cryptogamie, Bryologie 20 (22) on page 290, DOI: 10.5252/cryptogamie-bryologie2019v40a22, http://zenodo.org/record/7822134
LeXInt: GPU-accelerated Exponential Integrators package
Creators: name: Deka, Pranab J
name: Moriggl, Alexander
name: Einkemmer, Lukas
Publisher: name: arXiv
Year: 2023
Subjects: subject: Numerical Analysis (math.NA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Mathematical Physics (math-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We present an open-source CUDA-based package that consists of a compilation of exponential integrators where the action of the matrix exponential or the $φ_l$ functions on a vector is approximated using the method of polynomial interpolation at Leja points. Using a couple of test examples on an NVIDIA A100 GPU, we show that one can achieve significant speedups using CUDA over the corresponding CPU code. LeXInt, written in a modular format, facilitates easy integration into any existing software package, and can be used for temporal integration of any differential equation.
description: Open-source code available at https://github.com/Pranab-JD/LeXInt; Comments & suggestions are highly welcome; if you need help using the software, please reach out
Notothylas orbicularis A. Gray
Creators: name: Rimac, Anja
name: Šegota, Vedran
name: Alegro, Antun
name: Koletić, Nikola
name: Vuković, Nina
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Plantae
Anthocerotophyta
Anthocerotopsida
Notothyladales
Notothyladaceae
Notothylas
Notothylas orbicularis

description: Notothylas orbicularis (Schwein.) A. Gray
 SPECIMEN EXAMINED. — Croatia. Nebojan Village, open ground on the lawn in a yard, 45.4959°N, 16.2038°E, 176 m a.s.l., 7.VIII.2018, leg. Rimac A., det. Rimac A. & Šegota V., ZA[ZA49736].
description: Published as part of Rimac, Anja, Šegota, Vedran, Alegro, Antun, Koletić, Nikola & Vuković, Nina, 2019, Novelties in the hornwort flora of Croatia and Southeast Europe, pp. 289-295 in Cryptogamie, Bryologie 20 (22) on page 291, DOI: 10.5252/cryptogamie-bryologie2019v40a22, http://zenodo.org/record/7822134
Cascading Constraints from Neutrino Emitting Blazars: The case of TXS 0506+056
Creators: name: Reimer, Anita
name: Boettcher, Markus
name: Buson, Sara
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present a procedure to generally constrain the environments of neutrino-producing sites in photomeson production models of jetted Active Galactic Nuclei (AGN) where any origin of the dominant target photon field can be accommodated. For this purpose we reconstruct the minimum target photon spectrum required to produce the (observed) neutrino spectrum, and derive the distributions of all corresponding secondary particles. These initiate electromagnetic cascades with an efficiency that is linked to the neutrino production rate. The derived photon spectra represent the minimum radiation emerging from the source that is strictly associated with the photo-hadronically produced neutrinos. Using the 2014-15 neutrino spectrum observed by IceCube from TXS 0506+056, we conduct a comprehensive study of these cascade spectra and compare them to the simultaneous multi-wavelength emission. For this set of observations, photopion production from a co-spatially produced (co-moving) photon target can be ruled out as well as a setup where synchrotron or Compton-synchrotron supported cascades on a stationary (AGN rest frame) target photon field operate in this source. However, a scenario where Compton-driven cascades develop in the stationary soft-X-ray photon target which photo-hadronically produced the observed neutrinos appears feasible with required proton kinetic jet powers near the Eddington limit. The source is then found to produce neutrinos inefficiently, and emits GeV photons significantly below the observed Fermi-LAT-flux. Hence, the neutrinos and the bulk of the gamma rays observed in 2014/2015 from TXS 0506+056 cannot have been initiated by the same process.
description: 19 pages, 18 figures. Affiliation corrected. Accepted by ApJ