cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons
Creators: name: Lowery-Gionta, Emily
name: Tecott, Laurence H.
name: Urban, Daniel J.
name: Aryal, Dipendra K.
name: Michaelides, Michael
name: Oshibuchi, Hidehiro
name: Hurd, Yasmin L.
name: Wetsel, William C.
name: Rhea, Darren
name: Zhu, Hu
name: Olsen, Reid H. J.
name: Kash, Thomas L.
name: Marcinkiewcz, Catherine A.
name: Roth, Bryan L.
name: Farrell, Martilias S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Elucidating how the brain's serotonergic network mediates diverse behavioral actions over both relatively short (minutes–hours) and long period of time (days–weeks) remains a major challenge for neuroscience. Our relative ignorance is largely due to the lack of technologies with robustness, reversibility, and spatio-temporal control. Recently, we have demonstrated that our chemogenetic approach (eg, Designer Receptors Exclusively Activated by Designer Drugs (DREADDs)) provides a reliable and robust tool for controlling genetically defined neural populations. Here we show how short- and long-term activation of dorsal raphe nucleus (DRN) serotonergic neurons induces robust behavioral responses. We found that both short- and long-term activation of DRN serotonergic neurons induce antidepressant-like behavioral responses. However, only short-term activation induces anxiogenic-like behaviors. In parallel, these behavioral phenotypes were associated with a metabolic map of whole brain network activity via a recently developed non-invasive imaging technology DREAMM (DREADD Associated Metabolic Mapping). Our findings reveal a previously unappreciated brain network elicited by selective activation of DRN serotonin neurons and illuminate potential therapeutic and adverse effects of drugs targeting DRN neurons.
Population dynamics of Paranomus spathulatus in Garcia state forest, Langeberg, site 3321CC/1
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Langeberg
population dynamics
Paranomus spathulatus
Garcia state forest

description: This is a scanned copy of a document on the population dynamics of Paranomus spathulatus in Garcia state forest, Langeberg, site 3321CC/1. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
title: Hidden Probabilistic One-Counter Automata
Creators: name: Kurucan, Mehmet
Publisher: name: University of Liverpool Repository
Year: 2025

description: This thesis furthers the ongoing study of devising faster algorithms for the learning problem of infinite-state systems. We examine the Hidden Probabilistic One-Counter Machine (HP1CA) model, a natural extension of both Probabilistic One-Counter Automata (P1CA) and Hidden Markov Model (HMM) in this thesis. HP1CAs allow for the quadratic time complexity of learning the parameters of the model based on observational data. This gives them a big advantage over other infinite-state systems, e.g., probabilistic pushdown automata for which the same task requires cubic time. An HP1CA is a P1CA where both the control states and the counter values are hidden, but the output sequence is not (note that there is no input sequence). Such a model has a non-negative counter whose value can change by at most one during a transition. The probability of a transition depends only on the current control state and whether the counter value is zero or not. The probability of a given output symbol depends on the current control state, but not on the value of the counter. A sequence of transitions is valid only if it starts and ends in a special initial control state and final control state, respectively, with the counter value equal zero. After introducing the model, we adapt Baum-Welch algorithm, which is a special case of the Expectation-Maximization algorithm used in unsupervised learning in HMM, to update the parameters of an HP1CA. Furthermore, we also adopted two dynamic programming algorithms which are called Forward algorithm and Backward algorithm, respectively to our new model. Our adapted algorithms have worst-case quadratic time complexity as compared to the linear time for HMM. At the same time, its complexity is linear if the maximum value of the counter is assumed to be bounded by a constant (as it is commonly in practice). After that, we look at other possible HP1CA models that differ depending on the semantic of what a valid transition sequence is. This can depend on the initial and final terminal state conditions as follows. First, an HP1CA can either start in (1) a fixed control state with counter zero or (2) have multiple initial control states, and some fixed probability distribution specifies the likelihood of starting in a given control state (with a counter value zero). Second, an HP1CA may be required to end with (A) a unique final control state with counter value zero, (B) a unique final control state with arbitrary counter value, (C) multiple final control states with zero counter value. This gives rise to six possible semantics, and only (1-A) semantic studied by us earlier. We adapt the learning and dynamic programming algorithms to the remaining five models. In the end, we demonstrate that our HP1CA model leads to better accuracy and lower fit error of observation sequences as compared to HMMs through an implementation.
Sonnenfleckenzeichnung Nr. 28577.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.07.1992, erstellt von Hans Ulrich Keller
Creators: name: Eidgenössische Sternwarte in Zürich (ETH Zürich bzw. vor 1911 Polytechnikum)
Publisher: name: [s.n.]
Year: 1992

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der ehem. Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit den statistischen Angaben, für die Werte g, f und mit einer Spalte für A: von blossem Auge sichtbare Flecken, beobachtet mit Hilfe eines korrekt-reduzierenden optischen Filters (naked eye sunspots).
Beobachtungstätigkeit am erwähnten Ort im Auftrag des Schweizerischen Militärdepartements, Bundesamt für Übermittlungstruppen (BAUEM): Zählungen am Fraunhoferschen Normalrefraktor und Zeichnungen am Zeiss-Coudé-Refraktor
title: Veränderung der Choriokapillaris in der Umgebung einer CNV bei exsudativer AMD
Creators: name: Wilming, Pia
name: Rothaus, K.
name: Farecki, M.L.
name: Faatz, H.
name: Ziegler, M.
name: Gutfleisch, M.
name: Spital, G.
name: Lommatzsch, A.
name: Pauleikhoff, D.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Bisher wurde angenommen, dass die Choriokapillaris (CC) im Rahmen der exsudativen AMD nur lokalisiert „dekompensiert“, allerdings sind in der OCT-A Veränderungen der CC in der direkten CNV-Umgebung zu beobachten. Ziel der Studie ist es aufzuzeigen, inwiefern sich die CC[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 181. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte
Sonnenfleckenzeichnung Nr. 28603.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.08.1992, erstellt von Hans Ulrich Keller
Creators: name: Eidgenössische Sternwarte in Zürich (ETH Zürich bzw. vor 1911 Polytechnikum)
Publisher: name: [s.n.]
Year: 1992

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der ehem. Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit den statistischen Angaben, für die Werte g, f und mit einer Spalte für A: von blossem Auge sichtbare Flecken, beobachtet mit Hilfe eines korrekt-reduzierenden optischen Filters (naked eye sunspots).
Beobachtungstätigkeit am erwähnten Ort im Auftrag des Schweizerischen Militärdepartements, Bundesamt für Übermittlungstruppen (BAUEM): Zählungen am Fraunhoferschen Normalrefraktor und Zeichnungen am Zeiss-Coudé-Refraktor
Optimal protocols for slowly-driven quantum processes
Creators: name: Zulkowski, Patrick R.
name: DeWeese, Michael R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The design of efficient quantum information processing will rely on optimal nonequilibrium transitions of driven quantum systems. Building on a recently-developed geometric framework for computing optimal protocols for classical systems driven in finite-time, we construct a general framework for optimizing the average information entropy for driven quantum systems. Geodesics on the parameter manifold endowed with a positive semi-definite metric correspond to protocols that minimize the average information entropy production in finite-time. We use this framework to explicitly compute the optimal entropy production for a simple two-state quantum system coupled to a heat bath of bosonic oscillators, which has applications to quantum annealing.
Lateral Hypothalamus GABAergic Neurons Modulate Consummatory Behaviors Regardless of the Caloric Content or Biological Relevance of the Consumed Stimuli
Creators: name: Burnham, Nathan W
name: Thiele, Todd E.
name: Mazzone, Christopher M
name: Navarro, Montserrat
name: Olney, Jeffrey J
name: Kash, Thomas L
name: Pleil, Kristen E
name: Lowery-Gionta, Emily G
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: It was recently reported that activation of a subset of lateral hypothalamus (LH) GABAergic neurons induced both appetitive (food-seeking) and consummatory (eating) behaviors in vGat-ires-cre mice, while inhibition or deletion of GABAergic neurons blunted these behaviors. As food and caloric-dense liquid solutions were used, the data reported suggest that these LH GABAergic neurons may modulate behaviors that function to maintain homeostatic caloric balance. Here we report that chemogenetic activation of this GABAergic population in vGat-ires-cre mice increased consummatory behavior directed at any available stimulus, including those entailing calories (food, sucrose, and ethanol), those that do not (saccharin and water), and those lacking biological relevance (wood). Chemogenetic inhibition of these neurons attenuated consummatory behaviors. These data indicate that LH GABAergic neurons modulate consummatory behaviors regardless of the caloric content or biological relevance of the consumed stimuli.
以EGFR少见突变及TMB高的为主要特征的非小细胞肺癌患者
Creators: name: 刘寅强(Yinqiang Liu)
Publisher: name: CNGB
Year: 2023
Subjects: Variation
Multiisolate
Medical

description: 通过二代测序（NGS）的方法，明确一群以EGFR少见突变及TMB高的为主要特征的非小细胞肺癌患者，分析EGFR少见突变肺癌小分子抑制剂的治疗疗效
title: Screening bei Patienten unter Hydroxy-/Chloroquintherapie
Creators: name: Freimuth, Marc-Aurel
name: Rating, P.
name: Bornfeld, N.
name: Bechrakis, N.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die ersten Zeichen einer toxischen Makulopathie lassen sich durch geeignete Untersuchungsverfahren vor Symptombeginn feststellen. Eine späte Diagnosestellung kann mit irreversiblem Visusverlust einhergehen, andererseits ist ein Absetzen der Therapie ohne Hinweis auf eine toxische [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 181. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte
title: Virtuelle Implantation von Intraokularlinsen mit Zusatzfunktionen bei Patienten mit Makulaerkrankungen
Creators: name: Kaymak, Hakan
name: Nienhaus, S.
name: Fricke, A.
name: Breyer, D.R.H.
name: Klabe, K.
name: Langenbucher, A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die funktionellen Ergebnisse nach Implantation von Multifokallinsen bei Patienten mit Makulaerkrankungen sind systematisch bisher nicht untersucht worden. Hier präsentieren wir unsere Ergebnisse. Methoden: Die zu testenden Intraokularlinsen (asphärische monofokale IOL (L1),[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 181. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte
Supplementary documentation for SAEON's field instrument data collected at the Cathedral Peak 3C station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cathedral Peak
Meteorological
Tipping bucket
Precipitation

description: This package contains supporting information for the meteorological data collected at Cathedral Peak's 3C station, as part of the South African Environmental Observation Network's monitoring projects.
Maltreatment Exposure, Brain Structure and Fear Conditioning in Children and Adolescents
Creators: name: Gold, Andrea L.
name: Wojcieszak, Zuzanna
name: McLaughlin, Katie A.
name: Pine, Daniel S.
name: Lambert, Hilary K.
name: Peverill, Matthew
name: Shechner, Tomer
name: Heleniak, Charlotte
name: Sheridan, Margaret A.
name: Duys, Andrea
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Alterations in learning processes and the neural circuitry that supports fear conditioning and extinction represent mechanisms through which trauma exposure might influence risk for psychopathology. Few studies examine how trauma or neural structure relates to fear conditioning in children. Children (n=94) aged 6–18 years, 40.4% (n=38) with exposure to maltreatment (physical abuse, sexual abuse, or domestic violence), completed a fear conditioning paradigm utilizing blue and yellow bells as conditioned stimuli (CS+/CS−) and an aversive alarm noise as the unconditioned stimulus. Skin conductance responses (SCR) and self-reported fear were acquired. Magnetic resonance imaging data were acquired from 60 children. Children without maltreatment exposure exhibited strong differential conditioning to the CS+ vs CS−, based on SCR and self-reported fear. In contrast, maltreated children exhibited blunted SCR to the CS+ and failed to exhibit differential SCR to the CS+ vs CS− during early conditioning. Amygdala and hippocampal volume were reduced among children with maltreatment exposure and were negatively associated with SCR to the CS+ during early conditioning in the total sample, although these associations were negative only among non-maltreated children and were positive among maltreated children. The association of maltreatment with externalizing psychopathology was mediated by this perturbed pattern of fear conditioning. Child maltreatment is associated with failure to discriminate between threat and safety cues during fear conditioning in children. Poor threat–safety discrimination might reflect either enhanced fear generalization or a deficit in associative learning, which may in turn represent a central mechanism underlying the development of maltreatment-related externalizing psychopathology in children.
Projection predictive model selection for Gaussian processes
Creators: name: Piironen, Juho
name: Vehtari, Aki
Publisher: name: arXiv
Year: 2015
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: We propose a new method for simplification of Gaussian process (GP) models by projecting the information contained in the full encompassing model and selecting a reduced number of variables based on their predictive relevance. Our results on synthetic and real world datasets show that the proposed method improves the assessment of variable relevance compared to the automatic relevance determination (ARD) via the length-scale parameters. We expect the method to be useful for improving explainability of the models, reducing the future measurement costs and reducing the computation time for making new predictions.
description: A few minor changes in text
title: Erfolgreiche Nanosekunden-Laser-Behandlung bei Chorioretinopathia Centralis Serosa in Abhängigkeit von der Autofluoreszenz
Creators: name: Funk, Saskia
name: Breyer, D.R.H.
name: Klabe, K.
name: Fulga, R.
name: Kaymak, H.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Chorioretinopathia Centralis Serosa (CCS) ist eine ein- oder beidseitige Makulaerkrankung mit einer Abhebung der neurosensorischen Retina. Die Spontanresorption der subretinalen Flüssigkeit (SRF) bei der akuten CCS liegt bei etwa 68% innerhalb von 4 Monaten und 84% innerhalb[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 181. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte
Sonnenfleckenzeichnung Nr. 28594.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.07.1992, erstellt von Hans Ulrich Keller
Creators: name: Eidgenössische Sternwarte in Zürich (ETH Zürich bzw. vor 1911 Polytechnikum)
Publisher: name: [s.n.]
Year: 1992

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der ehem. Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit den statistischen Angaben, für die Werte g, f und mit einer Spalte für A: von blossem Auge sichtbare Flecken, beobachtet mit Hilfe eines korrekt-reduzierenden optischen Filters (naked eye sunspots).
Beobachtungstätigkeit am erwähnten Ort im Auftrag des Schweizerischen Militärdepartements, Bundesamt für Übermittlungstruppen (BAUEM): Zählungen am Fraunhoferschen Normalrefraktor und Zeichnungen am Zeiss-Coudé-Refraktor
Constraints to the magnetospheric properties of T Tauri stars - II. The Mg II ultraviolet feature
Creators: name: Lopez-Martinez, Fatima
name: de Castro, Ana Ines Gomez
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The atmospheric structure of T Tauri Stars (TTSs) and its connection with the large scale outflow is poorly known. Neither the effect of the magnetically mediated inter- action between the star and the disc in the stellar atmosphere is well understood. The Mg II multiplet is a fundamental tracer of TTSs atmospheres and outflows, and is the strongest feature in the near-ultraviolet spectrum of TTSs. The International Ultraviolet Explorer and Hubble Space Telescope data archives provide a unique set to study the main physical compounds contributing to the line profile and to derive the properties of the line formation region. The Mg II profiles of 44 TTSs with resolution 13,000 to 30,000 are available in these archives. In this work, we use this data set to measure the main observables: flux, broadening, asymmetry, terminal velocity of the outflow, and the velocity of the Discrete Absorption Components. For some few sources repeated observations are available and variability has been studied. There is a warm wind that at sub-AU scales absorbs the blue wing of the Mg II profiles. The main result found in this work is the correlation between the line broadening, Mg II flux, terminal velocity of the flow and accretion rate. Both outflow and magnetospheric plasma contribute to the Mg II flux. The flux-flux correlation between Mg II and C IV or He II is confirmed; however, no correlation is found between the Mg II flux and the ultraviolet continuum or the H2 emission.
description: 21 pages, 20 figures
Personenarchiv Wengen-Meyenrock, Fanny Rosalie à, Witwe, Rentière
Creators: name: Wengen-Meyenrock, Fanny Rosalie à
Publisher: name: [s.n.]
Year: 1891
Subjects: Haushaltsbuch
Treuhand
Unternehmensberatung

description: Enthält: 1 Hauptbuch
description: Firmensitz / Wohnsitz: Basel
description: Zeitraum des Bestehens / Lebensdaten: ?-?
description: Trägermaterial: Papier
description: Archivalienart: Manuskript
description: Geschenk
description: Deutsch
description: Zettelkatalog, Detailverzeichnis (gedruckt und als PDF)
description: Verzeichnung=Description=Inventaire Jahr unbekannt Erschliessungsgrad: Detailliert Bearbeiter/in unbekannt Akzession 1
title: Vergleichende Analyse der Lebenszeitexpression von PARK7/DJ-1 in dem Choroidea-Pigmentepithel-Komplex von Callithrix jacchus in Bezug zur Topographie
Creators: name: Lever, Mael
name: Hadrian, K.
name: Thanos, S.
name: Schlatt, S.
name: Wistuba, J.
name: König, S.
name: Bechrakis, N.E.
name: Böhm, M.R.R.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Altersbedingte strukturelle Veränderungen des Aderhaut-retinales Pignentepithel-Komplex (CC-RPE) tragen zur Entstehung von neurodegenerativen Netzhauterkrankungen bei. Oxidativer Stress zählt zu den wichtigen Pathomechanismen für das Auftreten solcher Erkrankungen. Die protektiven,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 181. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte
Mu Opioid Receptor Modulation of Dopamine Neurons in the Periaqueductal Gray/Dorsal Raphe: A Role in Regulation of Pain
Creators: name: McElligott, Zoe A
name: Lopez, Alberto J
name: McCall, Nora M
name: McKlveen, Jessica M
name: Kash, Thomas L
name: Lowery-Gionta, Emily G
name: Pleil, Kristen E
name: Li, Chia
name: Sugam, Jonathan A
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The periaqueductal gray (PAG) is a brain region involved in nociception modulation, and an important relay center for the descending nociceptive pathway through the rostral ventral lateral medulla. Given the dense expression of mu opioid receptors and the role of dopamine in pain, the recently characterized dopamine neurons in the ventral PAG (vPAG)/dorsal raphe (DR) region are a potentially critical site for the antinociceptive actions of opioids. The objectives of this study were to (1) evaluate synaptic modulation of the vPAG/DR dopamine neurons by mu opioid receptors and to (2) dissect the anatomy and neurochemistry of these neurons, in order to assess the downstream loci and functions of their activation. Using a mouse line that expresses eGFP under control of the tyrosine hydroxylase (TH) promoter, we found that mu opioid receptor activation led to a decrease in inhibitory inputs onto the vPAG/DR dopamine neurons. Furthermore, combining immunohistochemistry, optogenetics, electrophysiology, and fast-scan cyclic voltammetry in a TH-cre mouse line, we demonstrated that these neurons also express the vesicular glutamate type 2 transporter and co-release dopamine and glutamate in a major downstream projection structure—the bed nucleus of the stria terminalis. Finally, activation of TH-positive neurons in the vPAG/DR using Gq designer receptors exclusively activated by designer drugs displayed a supraspinal, but not spinal, antinociceptive effect. These results indicate that vPAG/DR dopamine neurons likely play a key role in opiate antinociception, potentially via the activation of downstream structures through dopamine and glutamate release.
Personenarchiv Burckhardt-Keller, Johann Jakob, Deputat
Creators: name: Burckhardt-Keller, Johann Jakob
Publisher: name: [s.n.]
Year: 1756
Subjects: Haushalt
Privater Haushalt

description: Enthält: 1 Briefkopierbuch
description: Darin: Lose Einlagen in separatem Umschlag
description: Firmensitz / Wohnsitz: Basel
description: Zeitraum des Bestehens / Lebensdaten: 17??-1820
description: Trägermaterial: Papier
description: Archivalienart: Manuskript
description: Alphons Koechlin Basel Geschenk 1954
description: Johann Jakob Burckhardt-Keller (17??-1820) bewohnte das Haus Fortuna, St. Johannsvorstadt in Basel. Er war mit Salomé Keller (1754-1792) verheiratet.
description: Französisch und Deutsch
description: Zettelkatalog, Detailverzeichnis (gedruckt und als PDF)
description: Der Band wurde dem SWA 1954 zusammen mit Unterlagen der Firma Thurneysen & Cie. (SWA HS 243) von Alphons Koechlin überreicht.
description: Verzeichnung=Description=Inventaire 1955 Erschliessungsgrad: Detailliert Hans Schaub Akzession 1954
Supplementary documentation for SAEON's field instrument data collected at the Cathedral Peak Ground level Mike's MET station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cathedral Peak
Meteorological
Tipping bucket
Precipitation

description: This package contains supporting information for the meteorological data collected at Cathedral Peak's Ground level Mike's MET station, as part of the South African Environmental Observation Network's monitoring projects.
Von Kooperation bis Netzwerkökonomie. Digitale Transformation verändert die Wertschöpfungsarchitektur
Creators: name: Lengsfeld, Jörn
Publisher: name: Zenodo
Year: 2023
Subjects: subject: Digital Transformation
subject: Digitization
subject: Digitalization
subject: Value Architecture
subject: Value Creation
subject: Value Chain
subject: Network Economy
subject: Interaction
subject: https://joernlengsfeld.com/en/definition/digital-transformation/
subject: https://joernlengsfeld.com/de/definition/digitalisierung/
subject: https://joernlengsfeld.com/de/definition/wertschoepfungsarchitektur/
subject: https://joernlengsfeld.com/de/definition/wertschoepfungskonzeption/
subject: https://joernlengsfeld.com/de/definition/wertschoepfungsgefuege/
subject: https://joernlengsfeld.com/de/definition/wertschoepfungsgeflecht/
subject: https://joernlengsfeld.com/de/definition/wertschoepfungskette/
subject: https://joernlengsfeld.com/de/definition/netzwerkoekonomie/
subject: https://joernlengsfeld.com/de/definition/wertschoepfung/
subject: https://joernlengsfeld.com/de/definition/interaktion/
subject: https://joernlengsfeld.com/de/definition/interaktionswissenschaften/
subject: https://joernlengsfeld.com/de/definition/funktionslogik/

description: Der Digitale Wandel verändert die Zusammenarbeit. Zwischen Menschen und zwischen Unternehmen. Spontan denken wir vielleicht an Videokonferenzen, Kollaborationssoftware und Automatisierung. Doch der Wandel geht tiefer: Es ändert sich die Art und Weise von Kooperation an sich. Interaktion vollzieht sich nach neuen Regeln. Prozesse werden umgestaltet. Kundennutzen entsteht unter neuen Bedingungen. Schließlich etabliert sich im Markt eine neue Funktionslogik: Die Netzwerkökonomie. Was folgt daraus für Unternehmer und Gründer? Chancen? Herausforderungen? Potentiale!
Fynbos population dynamics, Lebanon State Forest, Houwhoek, site 3419AA/11
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Fynbos
population dynamics
Lebanon State Forest
Houwhoek
Helichrysum
Protea
Serruria
Erica
Leucadendron
Tolpis
Brunia

description: This is a scanned copy of a document on fynbos population dynamics, Lebanon State Forest, Houwhoek, site 3419AA/11. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape.  SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
Caraipa caespitosa F. N. Cabral
Creators: name: Cabral, Fernanda Nunes
name: Bittrich, Volker
name: Hopkins, Michael John Gilbert
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Calophyllaceae
Caraipa
Caraipa caespitosa

description: 2.1 Caraipa caespitosa F.N. Cabral in Cabral et al. (2016b: 248) (Fig. 2D–F)
 Type:— BRAZIL. Roraima: Caracaraí, Parque Nacional do Viruá, igarapé Anauá, 23 March 2008, fr., Ferreira et al. 13082 (holotype: INPA!, barcode 253111).
Shrubs, up to 70 cm tall, with numerous (20–40) sparsely branched stems growing from a mound. Exudate cream or translucid. Leaves distichous, leaf blade 4–7.5 × 1.8–4.5 cm, coriaceous, elliptical to oval, apex rounded to acute or obtuse, base cordate to rounded, adaxial surface glabrous, abaxial surface with minute sessile stellate trichomes or glabrous, with bulliform cells; secondary veins 11–22 pairs, distant 4–6 mm; petiole 2.4–7.6(–10.5) mm long. Panicule, (1–)3–14-flowered, peduncle and pedicels tomentose, pedicel 3–13 mm long. Sepal lobes 2–4 × 2–4 mm. Petals 14–27 × 10–14 mm. Stamens 3–10 mm long, gland at the apex of the thecae. Ovary ca. 2 mm across, style ca. 4 mm long. Fruit 17–26 × 14–19 mm, ovoid to pyramidal, rugulose to smooth, densely covered with sessile and stipitate stellate hairs, exocarp separating from endocarp. Seeds ca. 10 × 8 mm.
 Phenology:—Flowering September to December; fruiting January to March.
 Distribution and habitat:— Brazil and Venezuela. In Brazil, it occurs in the north region (states of Amazonas and Roraima). Caraipa caespitosa occurs on white-sand vegetation.
 Specimens examined:— BRAZIL. Roraima: Caracaraí, Viruá National Park, elevation 62 m, 1º25’32’’N, 60º59’13’’W, 3 December 2009, fl., Cabral et al. 101 (INPA); Ibid., 1º23’39’’N, 61º13’25’’W, 22 January 2010, fr., Cabral et al. 167 (INPA); Ibid., 14 September 2010, fl., Cabral et al. 270 (INPA); Ibid., 12 October 2010, fl., Cabral et al. 294 (INPA) .
 Additional specimens:— BRAZIL. Amazonas: Final da Perimetral 1—Norte da Perimetral Norte (RR210), 25 March 1999, fr., Vicentini 1416 (MO!).
 Taxonomic notes:— Caraipa caespitosa is morphologically similar to C. grandifolia and C. longipedicellata. Caraipa caespitosa can be easily distinguished by its habit, which is small shrub with numerous sparsely branched stems growing from a mound, versus trees in C. grandifolia and C. longipedicellata. The species can also be identified by leaf size, number of secondary veins, and inflorescence size, see Cabral et al. (2016b) for more details.
description: Published as part of Cabral, Fernanda Nunes, Bittrich, Volker & Hopkins, Michael John Gilbert, 2017, Clusiaceae s. l. (Calophyllaceae, Clusiaceae s. s. and Hypericaceae) in the Viruá National Park, Roraima, Brazil, pp. 1-27 in Phytotaxa 329 (1) on pages 6-7, DOI: 10.11646/phytotaxa.329.1.1, http://zenodo.org/record/13721722
Attenuation of Frontostriatal Connectivity During Reward Processing Predicts Response to Psychotherapy in Major Depressive Disorder
Creators: name: Petty, Chris
name: Crowther, Andrew
name: Dichter, Gabriel S
name: Smoski, Moria J
name: Eisenlohr-Moul, Tory
name: Carl, Hannah
name: Gibbs, Devin
name: Walsh, Erin
name: Moore, Tyler
name: Minkel, Jared
name: Bizzell, Josh
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: There are few reliable predictors of response to antidepressant treatments. In the present investigation, we examined pretreatment functional brain connectivity during reward processing as a potential predictor of response to Behavioral Activation Treatment for Depression (BATD), a validated psychotherapy that promotes engagement with rewarding stimuli and reduces avoidance behaviors. Thirty-three outpatients with major depressive disorder (MDD) and 20 matched controls completed two runs of the monetary incentive delay task during functional magnetic resonance imaging after which participants with MDD received up to 15 sessions of BATD. Seed-based generalized psychophysiological interaction analyses focused on task-based connectivity across task runs, as well as the attenuation of connectivity from the first to the second run of the task. The average change in Beck Depression Inventory-II scores due to treatment was 10.54 points, a clinically meaningful response. Groups differed in seed-based functional connectivity among multiple frontostriatal regions. Hierarchical linear modeling revealed that improved treatment response to BATD was predicted by greater connectivity between the left putamen and paracingulate gyrus during reward anticipation. In addition, MDD participants with greater attenuation of connectivity between several frontostriatal seeds, and midline subcallosal cortex and left paracingulate gyrus demonstrated improved response to BATD. These findings indicate that pretreatment frontostriatal functional connectivity during reward processing is predictive of response to a psychotherapy modality that promotes improving approach-related behaviors in MDD. Furthermore, connectivity attenuation among reward-processing regions may be a particularly powerful endophenotypic predictor of response to BATD in MDD.
Population dynamics of Protea nitida and Protea arborea in the Cederberg, Groot Koupoort (Heuningvlei), site 3219AC/9
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
population dynamics
Protea nitida
Protea arborea
Groot Koupoort
Heuningvlei
Cederberg

description: This is a scanned copy of the population dynamics of Protea nitida and Protea arborea in the Cederberg, Groot Koupoort (Heuningvlei), site 3219AC/9. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
title: Rethinking Contemporary Feminist Activism: Zines, Social Media and Body Politics in the Fourth-Wave
Creators: name: Matich, Margaret
Publisher: name: University of Liverpool Repository
Year: 2525

description: By focusing on feminist zines and zine communities as a significant platform where contemporary feminists are waging their war on the kyriarchy, this thesis presents a cross-section of contemporary feminist activism by surfacing some of the key features of the fourth-wave. Employing an interpretivist feminist standpoint approach and an ethnographic study design, this thesis critically examines the online, offline and trans-generational means of transmission that fourth-wave feminists are using to assert their agency, autonomy and authorial presence, with the aim of disturbing the dominant, oppressive hegemonic ‘other’. The findings of this thesis draw out the micro, meso and macro level significance and impact of these practices. From my study findings, I argue that these practices provide vital enclaves of resistance and sanctuaries of solidarity, that allow feminists of the fourth-wave to develop identities, aesthetics, tactics, vocabularies and communities. I will suggest that these practices manifest in and reveal a type of ‘technical composting’ and ‘strategic nostalgia,’ whereby modern-day feminists are drawing on feminism’s ‘already there’ to reinvigorate longstanding practices and use them in nuanced reconfigurations within contemporary contexts. The study also examines how the body is being politicised and represented in these spaces. The findings show that by leveraging the intersectional, alienated and abject body, fourth-wave feminists are utilising their corporeal identities to push for visibility and representation in order to glitch the hegemonic regimes of the kyriarchy and to postulate new feminist futures. However, this work comes not without critique - the contemporary fourth-wave feminist quest for visibility and representation fosters an uneasy relationship with the market, and the threat of co-option, recuperation and sublimation pervade discussions around the nature of fourth-wave feminist activism.
Spontaneous stochasticity of velocity in turbulence models
Creators: name: Mailybaev, Alexei A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We analyze the phenomenon of spontaneous stochasticity in fluid dynamics formulated as the nonuniqueness of solutions resulting from viscosity at infinitesimal scales acting through intermediate on large scales of the flow. We study the finite-time onset of spontaneous stochasticity in a real version of the GOY shell model of turbulence. This model allows high-accuracy numerical simulations for a wide range of scales (up to ten orders of magnitude) and demonstrates non-chaotic dynamics, but leads to an infinite number of solutions in the vanishing viscosity limit after the blowup time. Thus, the spontaneous stochasticity phenomenon is clearly distinguished from the chaotic behavior in turbulent flows. We provide the numerical and theoretical description of the system dynamics at all stages. This includes the asymptotic analysis before and after the blowup leading to universal (periodic and quasi-periodic) renormalized solutions, followed by nonunique stationary states at large times.
description: 20 pages, 9 figures
title: Expression und Charakterisierung von Cathepsin B im retinalen Pigmentepithel
Creators: name: Hadrian, Karina
name: Lever, M.
name: Schlatt, S.
name: Wistuba, J.
name: Klein-Hitpass, L.
name: Rahmann, S.
name: König, S.
name: Thanos, S.
name: Bornfeld, N.
name: Bechrakis, N.E.
name: Böhm, M.R.R.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Während des Alterungsprozesses des Auges kommt es zu signifikanten molekularbiologischen Veränderungen des retinalen Pigmentepithels (RPE). In Vorarbeiten konnten in Transkriptom- und Proteomanalysen des alternden RPEs insbesondere eine erhöhte Expression von Cathepsin B [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 181. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte
Widdringtonia Cederbergensis enumeration in the Cedar Preserve, Cederberg
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Sneeukop
Cederberg

description: This is a scanned copy of a document noting a line intercept in the Cederberg, Sneeukop, site 3219AC/20. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
title: Operations-assoziierte unerwünschte Ereignisse des Argus II Retinaprothesensystems
Creators: name: Schaffrath, Kim
name: Schellhase, H.
name: Walter, P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Das Argus II Retinaprothesensystem (Second Sight Medical Products Inc., Sylmar, CA, USA) ist ein epiretinales Netzhaut-Implantat, das die verbliebene Sehfunktion von Patienten mit degenerativen Netzhauterkrankungen, beispielsweise Retinitis pigmentosa, unterstützen und verbessern soll.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 181. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte
Metrics for Optimization of Large Synoptic Survey Telescope Observations of Stellar Variables and Transients
Creators: name: Lund, Michael B.
name: Siverd, Robert J.
name: Pepper, Joshua A.
name: Stassun, Keivan G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The Large Synoptic Survey Telescope (LSST) will be the largest time-domain photometric survey ever. In order to maximize the LSST science yield for a broad array of transient stellar phenomena, it is necessary to optimize the survey cadence, coverage, and depth via quantitative metrics that are specifically designed to characterize the time-domain behavior of various types of stellar transients. In this paper we present three such metrics built on the LSST Metric Analysis Framework (MAF) model (Jones et al. 2014). Two of the metrics quantify the ability of LSST to detect non-periodic and/or non-recurring transient events, and the ability of LSST to reliably measure periodic signals of various timescales. The third metric provides a way to quantify the range of stellar parameters in the stellar populations that LSST will probe. We provide example uses of these metrics and discuss some implications based on these metrics for optimization of the LSST survey for observations of stellar variables and transients.
description: 17 pages, 19 figures; for submission to PASP
The route to magnetic order in the spin-$1/2$ kagome Heisenberg antiferromagnet: The role of interlayer coupling
Creators: name: Götze, Oliver
name: Richter, Johannes
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: While the existence of a spin-liquid ground state of the spin-1/2 kagome Heisenberg antiferromagnet (KHAF) is well established, the discussion of the effect of an interlayer coupling (ILC) by controlled theoretical approaches is still lacking. Here we study this problem by using the coupled-cluster method to high orders of approximation. We consider a stacked KHAF with a perpendicular ILC $J_\perp$, where we study ferro- as well as antiferromagnetic $J_\perp$. We find that the spin-liquid ground state (GS) persists until relatively large strengths of the ILC. Only if the strength of the ILC exceeds about 15\% of the intralayer coupling the spin-liquid phase gives way for $q=0$ magnetic long-range order, where the transition between both phases is continuous and the critical strength of the ILC, $|J^c_\perp|$, is almost independent of the sign of $J_\perp$. Thus, by contrast to the quantum GS selection of the strictly two-dimensional KHAF at large spin $s$, the ILC leads first to a selection of the $q=0$ GS. Only at larger $|J_\perp|$ the ILC drives a first-order transition to the $\sqrt{3}\times\sqrt{3}$ long-range ordered GS. As a result, the stacked spin-1/2 KHAF exhibits a rich GS phase diagram with two continuous and two discontinuous transitions driven by the ILC.
description: 7 pages, 3 figures, version as accepted in Europhys. Lett. (EPL), one formula and a few typos corrected
Binge-Like Alcohol Exposure During Adolescence Disrupts Dopaminergic Neurotransmission in the Adult Prelimbic Cortex
Creators: name: Pandey, Subhash C.
name: Mulholland, Patrick J.
name: Krishnan, Harish R.
name: Gass, Justin T.
name: Floresco, Stan B.
name: Judson Chandler,
name: Trantham-Davidson, Heather
name: Glover, Elizabeth J.
name: Crews, Fulton T.
name: Centanni, Samuel W.
name: Garr, S Corrin
name: New, Natasha N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Repeated binge-like exposure to alcohol during adolescence has been reported to perturb prefrontal cortical development, yet the mechanisms underlying these effects are unknown. Here we report that adolescent intermittent ethanol exposure induces cellular and dopaminergic abnormalities in the adult prelimbic cortex (PrL-C). Exposing rats to alcohol during early-mid adolescence (PD28–42) increased the density of long/thin dendritic spines of layer 5 pyramidal neurons in the adult PrL-C. Interestingly, although AIE exposure did not alter the expression of glutamatergic proteins in the adult PrL-C, there was a pronounced reduction in dopamine (DA) D1 receptor modulation of both intrinsic firing and evoked NMDA currents in pyramidal cells, whereas D2 receptor function was unaltered. Recordings from fast-spiking interneurons also revealed that AIE reduced intrinsic excitability, glutamatergic signaling, and D1 receptor modulation of these cells. Analysis of PrL-C tissue of AIE-exposed rats further revealed persistent changes in the expression of DA-related proteins, including reductions in the expression of tyrosine hydroxylase and catechol-O-methyltransferase (COMT). AIE exposure was associated with hypermethylation of the COMT promoter at a conserved CpG site in exon II. Taken together, these findings demonstrate that AIE exposure disrupts DA and GABAergic transmission in the adult medial prefrontal cortex (mPFC). As DA and GABA work in concert to shape and synchronize neuronal ensembles in the PFC, these alterations could contribute to deficits in behavioral control and decision-making in adults who abused alcohol during adolescence.