cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Absolutely Maximally Entangled states, combinatorial designs and multi-unitary matrices
Creators: name: Goyeneche, Dardo
name: Alsina, Daniel
name: Latorre, José I.
name: Riera, Arnau
name: Życzkowski, Karol
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Absolutely Maximally Entangled (AME) states are those multipartite quantum states that carry absolute maximum entanglement in all possible partitions. AME states are known to play a relevant role in multipartite teleportation, in quantum secret sharing and they provide the basis novel tensor networks related to holography. We present alternative constructions of AME states and show their link with combinatorial designs. We also analyze a key property of AME, namely their relation to tensors that can be understood as unitary transformations in every of its bi-partitions. We call this property multi-unitarity.
description: 18 pages, 2 figures. Comments are very welcome
Appendix
Creators: name: Pflügner
name: Maier, Christian
name: Thatcher, Jason Bennett
name: Mattke, Jens
name: Weitzel, Tim
Publisher: name: figshare
Year: 2023
Subjects: Information systems not elsewhere classified

description: Online Appendix to the paper "Deconstructing technostress: A configurational approach to explaining job burnout and job performance"
Point-of-use sensors in agriculture with cellulose fabric materials
Creators: name: Grell, Maximilian
Publisher: name: Imperial College London
Year: 2020

description: There is a compelling need for more efficient food production; 20% of farmland is now degraded due to over-intensive farming, only 6% of agricultural dry biomass gets eaten and the human population continues to rise. This need has fuelled the adoption of precision farming with point-of-use (PoU) sensors. In Chapter 1, I introduce the topic of this thesis by reviewing the PoU sensing mechanisms and devices that are emerging using cellulose fabrics, I then highlight the trends in recent applications. In Chapter 2, I present a low-cost method to grow metals such as Au, Ag and Pt autocatalytically inside the fibrous networks of cellulose fabrics. I demonstrate a range of applications including an electrochemical biosensor that uses metallised paper to measure DNA biomarkers of Mycobacterium avium spp. Paratuberculosis, the causative agent of Johne’s disease that affects ruminant animals such as cattle and sheep. In the future, this method of fabric metallisation may pave the way for new classes of PoU devices in life science and agricultural applications. In Chapter 3 I dive into soil nutrients. Most farmers have no way to measure their fertiliser requirements, so practical guidance leans toward over-fertilisation, to maximise yields. I demonstrate a robust and selective PoU NH4+ sensor that measures 3±1ppm in soil (R2=0.70), and a machine learning model that predicts NO3- (R2=0.87) from only PoU and weather data. Finally, I show how a recurrent neural network predicts NH4+ and NO3- up to 12 days into the future. The outlook is that farmers, with little or zero access to soil measurements, can predict crucial soil nutrients with enough accuracy to reduce over-fertilisation or improve crop yields. In closing, I consider the outlook for PoU sensors with cellulose fabrics in agriculture, the central role they will take in food production and the challenges they must overcome.
'THz Torch' wireless communications links
Creators: name: Ren, Hang
Publisher: name: Imperial College London
Year: 2020

description: The low-cost 'THz Torch’ technology, which exploits the thermal infrared spectrum (ca. 10 to 100 THz), was recently introduced to provide secure low data rate communications links across short ranges. In this thesis, the channel model for 'THz Torch’ wireless communications links is redeveloped from a thermodynamics perspective. Novel optimization-based channel estimators are also proposed to calibrate parameters in the channel model. Based on these theoretical advances, a cognitive 'THz Torch’ receiver, which combines conventional digital communications with state-of-the-art deep learning techniques, is presented to achieve cognitive synchronization and demodulation. The newly reported 'THz Torch’ wireless link is capable of bypassing the thermal time constant constraints normally associated with both the thermal emitter and sensor, allowing truly asynchronous data transfer with direct electronic modulation. Experimental results obtained in both laboratory environments and field trials demonstrate step-change improvements in channel range, bit rate, bit error rate and demodulation speed. This work represents a paradigm shift in modulation-demodulation with a thermal-based physical layer and offers a practical solution for implementing future ubiquitous secure 'THz Torch’ wireless communications links. The cognitive receiver concept also has wide-ranging implications for future communications and sensor technologies, making them more resilient when operating in harsh environments.
title: Anterior shoulder instability: Evaluation using MR arthrography.
Creators: name: Purohit, Neeraj
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Trauma
subject: Arthrography
subject: MR
subject: Extremities

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: We present a pictorialreview of the evaluation of anterior shoulder instability with MR Arthrography. Thedominant patternsof osseous and soft tissue pathologyare described along with key imaging findings. The following pathologies are shown: Bankart...
Tropomyosin Promotes Lamellipodial Persistence by Collaborating with Arp2/3 at the Leading Edge
Creators: name: Hardeman, Edna C.
name: Gunning, Peter W.
name: Bryce, Nicole S.
name: Bear, James E.
name: Schevzov, Galina
name: Haynes, Elizabeth M.
name: Brayford, Simon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: At the leading edge of migrating cells, protrusion of the lamellipodium is driven by Arp2/3-mediated polymerization of actin filaments [1]. This dense, branched actin network is promoted and stabilized by cortactin [2, 3]. In order to drive filament turnover, Arp2/3 networks are remodeled by proteins such as GMF, which blocks the actin-Arp2/3 interaction [4, 5], and coronin 1B, which acts by directing SSH1L to the lamellipodium where it activates the actin-severing protein cofilin [6, 7]. It has been shown in vitro that cofilin-mediated severing of Arp2/3 actin networks results in the generation of new pointed ends to which the actin-stabilizing protein tropomyosin (Tpm) can bind [8]. The presence of Tpm in lamellipodia, however, is disputed in the literature [9-19]. Here, we report that the Tpm isoforms 1.8/9 are enriched in the lamellipodium of fibroblasts as detected with a novel isoform-specific monoclonal antibody. RNAi-mediated silencing of Tpm1.8/9 led to an increase of Arp2/3 accumulation at the cell periphery and a decrease in the persistence of lamellipodia and cell motility, a phenotype consistent with cortactin- and coronin 1B-deficient cells [2, 7]. In the absence of coronin 1B or cofilin, Tpm1.8/9 protein levels are reduced while, conversely, inhibition of Arp2/3 with CK666 leads to an increase in Tpm1.8/9 protein. These findings establish a novel regulatory mechanism within the lamellipodium whereby Tpm collaborates with Arp2/3 to promote lamellipodial-based cell migration.
Quantum simulation of confinement dynamics
Creators: name: Vovrosh, Joseph William
Publisher: name: Imperial College London
Year: 2022

description: Quantum computers have generated much excitement over recent years due to their potential to outperform classical computers in many difficult problems. While a fully fault tolerant quantum device is yet to be built, there has been much work pushing for noisy intermediate-scale quantum (NISQ) devices to achieve quantum advantage. One of the most promising fields to accomplish this is in quantum simulation of quantum many-body systems. A classical computer is able to simulate a general quantum system but suffers from exponential memory requirements in system size. Thus, for exact results, classical computers are limited to simulating just tens of particles whereas realistic quantum systems are comprised of $\sim 10^{23}$. Quantum computers are able to reduce this memory cost to polynomial growth making them key to understand the physics of many-body systems. One area that is notably difficult to simulate is confinement physics. Confinement is the phenomenon in which the energy of two particles grows indefinitely with their separation - most prominently found between quarks in quantum chromodynamics (QCD). In this work we will consider the application of quantum devices to simulate such phenomena. In particular, we consider simple condensed matter systems, namely variations of the Ising model, that exhibit confinement physics. In the first half of this work we perform an analytical and numerical study of confinement, and develop a trotterization protocol to enable the quantum simulation of such physics on a digital quantum computer. We present results obtained directly on an IBM quantum computer showing the non-equilibrium effects of confinement in such systems. In order to achieve these results we developed state-of-the-art error mitigation methods to combat the large errors inherently faced in current NISQ devices. In the latter half, we propose physical phenomena that may act as a benchmark for quantum devices in the future. Collisions of mesons (boundstates of two particles) with impurities are considered in which a long-lived metastable state is found to form. Such collisions have potential to be simulated on digital quantum computers in the near future. We then consider collisions of mesons in systems with long-range interactions. We show how collisions of interacting mesons can lead to the formation of hadrons (boundstates of many constituent particles) in a fusion type event. While these proposals are beyond current digital quantum computer capabilities, analogue quantum simulation devices such as trapped ion setups or Rydberg atom experiments are well suited to realise this physics.
title: Imaging features of sinonasal lymphoma
Creators: name: Beh, Chan Yiing
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Lymphoma
subject: Education
subject: MR
subject: CT
subject: Head and neck

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To determine the imaging features of sinonasal lymphoma by a retrospective...
Efficient estimators for likelihood ratio sensitivity indices of complex stochastic dynamics
Creators: name: Arampatzis, Georgios
name: Katsoulakis, Markos A.
name: Rey-Bellet, Luc
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We demonstrate that centered likelihood ratio estimators for the sensitivity indices of complex stochastic dynamics are highly efficient with low, constant in time variance and consequently they are suitable for sensitivity analysis in long-time and steady-state regimes. These estimators rely on a new covariance formulation of the likelihood ratio that includes as a submatrix a Fisher Information Matrix for stochastic dynamics and can also be used for fast screening of insensitive parameters and parameter combinations. The proposed methods are applicable to broad classes of stochastic dynamics such as chemical reaction networks, Langevin-type equations and stochastic models in finance, including systems with a high dimensional parameter space and/or disparate decorrelation times between different observables. Furthermore, they are simple to implement as a standard observable in any existing simulation algorithms without additional modifications.
description: Revision of the paper. Added a new estimator
title: Organ doses and cancer LAR evaluations in scoliosis examinations with the EOS Imaging System
Creators: name: Branchini, Marco
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Radioprotection / Radiation dose
subject: Bones
subject: Teleradiology
subject: Conventional radiography
subject: Radiation safety
subject: Diagnostic procedure
subject: Teleradiology
subject: Dosimetric comparison

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The radiological investigation of spinal and bone structure deformity, both in adult and in pediatric patients, is an essential tool in the identification of pathological changes and in guiding the surgeon in choosing the best and least invasive...
A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges
Creators: name: Rehain-Bell, Kathryn
name: Werner, Michael E.
name: MacLeod, Ian
name: Love, Andrew
name: Maddox, Amy Shaub
name: Yates, John R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Germ cells in most animals are connected by intercellular bridges, actin-based rings that form stable cytoplasmic connections between cells promoting communication and coordination [1]. Moreover, these connections are required for fertility [1, 2]. Intercellular bridges are proposed to arise from stabilization of the cytokinetic ring during incomplete cytokinesis [1]. Paradoxically, proteins that promote closure of cytokinetic rings are enriched on stably open intercellular bridges [1, 3, 4]. Given this inconsistency, the mechanism of intercellular bridge stabilization is unclear. Here, we used the C. elegans germline as a model for identifying molecular mechanisms regulating intercellular bridges. We report that bridges are actually highly dynamic, changing size at precise times during germ cell development. We focused on the regulation of bridge stability by anillins, key regulators of cytokinetic rings and cytoplasmic bridges [1, 4-7]. We identified GCK-1, a conserved serine/threonine kinase [8], as a putative novel anillin interactor. GCK-1 works together with CCM-3, a known binding partner [9], to promote intercellular bridge stability and limit localization of both canonical anillin and non-muscle myosin II (NMM-II) to intercellular bridges. Additionally, we found that a shorter anillin, known to stabilize bridges [4, 7], also regulates NMM-II levels at bridges. Consistent with these results, negative regulators of NMM-II stabilize intercellular bridges in the Drosophila egg chamber [10, 11]. Together with our findings, this suggests that tuning of myosin levels is a conserved mechanism for the stabilization of intercellular bridges that can occur by diverse molecular mechanisms.
title: A pictorial review of common Müllerian duct anomalies
Creators: name: Chi, Hsi-Ping
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Obstetrics
subject: Developmental disease
subject: Congenital
subject: Hysterosalpingography
subject: MR
subject: Fluoroscopy
subject: Pelvis
subject: Obstetrics (Pregnancy / birth / postnatal period)
subject: Genital / Reproductive system female

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Understand the common Müllerian duct anomalies, their aetiologies and associated featuresbased on the processesof embryonic development Appreciate the ways in whichMüllerian duct anomalies can be diagnosed based on their radiological appearances...
The structure and dynamics of the near-sun solar wind
Creators: name: Woolley, Thomas
Publisher: name: Imperial College London
Year: 2022

description: The solar wind is a collisionless plasma that flows at hundreds of km/s away from the Sun into interplanetary space. Despite over half a century of solar wind research many questions remain unanswered. To address these questions, in situ data from small heliocentric distances is required. To date, Parker Solar Probe (PSP) is the only spacecraft to measure data within 0.29 au. Therefore, the PSP data set offers a unique opportunity to study the near-Sun solar wind. The data from the Solar Probe Cup instrument are fitted to extract bulk solar wind parameters. These parameters are used in conjunction with data from the SPAN and MAG instruments to analyse three structures found in the solar wind: switchbacks, patches and quiet periods. The ion velocity distribution functions within full-reversal switchbacks are shown to be consistent with a velocity-space rotation of the background plasma. This suggests that the proton core parallel temperature is the same inside and outside of full-reversal switchbacks despite the enhanced plasma velocity above the background. The solar wind associated with two switchback patches is found to be consistent with slow Alfv\'enic solar wind from near the boundary of the southern polar coronal hole. A patch is also found to have a particularly low $\alpha-$particle abundance which is in contrast to a subsequent study, suggesting that $\alpha-$particle abundance within patches is variable. Quiet periods are found to be consistent with longitudinal solar wind streams in close proximity to the heliospheric current sheet (HCS). The typical longitudinal scale size of these quiet periods is $\sim$2$^{\circ}$. However, most quiet period durations are not consistent with this scale, as they are modulated by PSP's orbital trajectory and the HCS dynamics.
title: The yield of magnetic resonance cholangiopancreatography in identifying choledocholithiasis in patients with suspected acute cholecystitis
Creators: name: Chi, Hsi-Ping
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Obstruction / Occlusion
subject: Inflammation
subject: Calcifications / Calculi
subject: Surgery
subject: Ultrasound
subject: MR
subject: Pancreas
subject: Biliary Tract / Gallbladder
subject: Anatomy

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Cholecystitis is typically investigated by ultrasound assessment of the biliary tract, which has good sensitivity and specificity in identifying gallbladder stones [1] This is routinely followed by magnetic resonance cholangiopancreatography (MRCP)...
Relativistic effects in Lyman-alpha forest
Creators: name: Iršič, Vid
name: Di Dio, Enea
name: Viel, Matteo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present the calculation of the Lyman-alpha (Lyman-$α$) transmitted flux fluctuations with full relativistic corrections to the first order. Even though several studies exist on relativistic effects in galaxy clustering, this is the first study to extend the formalism to a different tracer of underlying matter at unique redshift range ($z=2-5$). Furthermore, we show a comprehensive application of our calculations of the Quasar-Lyman-$α$ cross-correlation function. Our results indicate that the signal of relativistic effects is sizeable at Baryonic Acoustic Oscillation (BAO) scale mainly due to the large difference in density bias factors of our tracers. We construct an observable, the anti-symmetric part of the cross-correlation function, that is dominated by the relativistic signal and offers a new way to measure the relativistic terms at relatively small scales. The analysis shows that relativistic effects are important when considering cross-correlations between tracers with very different biases, and should be included in the data analysis of the current and future surveys. Moreover, the idea presented in this paper is highly complementary to other techniques and observable trying to isolate the effect of the relativistic corrections and thus test the validity of the theory of gravity beyond the Newtonian regime.
description: 39 pages, 9 figures; added sections on bias of the relativistic effects & S/N ratio analysis; version matches one published in JCAP
The Gribov Legacy, Gauge Theories and the Physical S-Matrix
Creators: name: White, Alan R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Reggeon unitarity and non-abelian gauge field copies are focussed on as two Gribov discoveries that, it is suggested, may ultimately be seen as the most significant and that could, in the far distant future, form the cornerstones of his legacy. The crucial role played by the Gribov ambiguity in the construction of gauge theory bound-state amplitudes via reggeon unitarity is described. It is suggested that the existence of a physical, unitary, S-Matrix in a gauge theory is a major requirement that could even determine the theory.
title: Identifying Posterior Cortical Atrophy (PCA) with multimodal and functional MRI
Creators: name: Heinz-Peer, Gertraud
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Image registration
subject: Dementia
subject: Diagnostic procedure
subject: Computer Applications-Detection, diagnosis
subject: MR-Functional imaging
subject: MR-Diffusion/Perfusion
subject: Image manipulation / Reconstruction
subject: Neuroradiology brain
subject: MR physics

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Teaching to identify Posterior Cortical Atrophy (PCA) with modern multimodal and functional...
title: Transitional cell carcinoma of the urinary tract: Topography oriented review
Creators: name: Pereira, Pedro
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: MR
subject: CT
subject: Urinary Tract / Bladder
subject: Pelvis
subject: Oncology
subject: Staging
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Review the role of imaging in the diagnosis, staging and surveillance of transitional cell carcinomas (TCCs); Illustrate the spectrum of appearances of TCCs according to the affected urinary tract segment, using cross-sectional imaging techniques;...
Iron biofortification: a much-needed strategy for prevailing conditions of micronutrient malnutrition
Creators: name: Mushtaq, Zain
name: Nazir, Anum
name: Jaffar, Muhammad Tauseef
Publisher: name: EQA - International Journal of Environmental Quality
Year: 2023

description: Micronutrient-malnutrition is one of the most serious battle human beings are fighting. The so-called Hidden hunger is all because of micronutrient deficiencies. Iron deficiency anemia is affecting more people than any other prevailing disorder. However, iron-supplementation aggravate the infectious diseases and present policies of iron therapy carefully evaluate the pros and cons. In current review, we have evaluated the biofortification approaches for combating hidden hunger, in the light of medical and nutritional advancements. Enhancement of iron in edible plant parts is expected to improve nutrient status of human beings via crops. The density of minerals and vitamins in staple foods consumed by the poor can be raised using either traditional plant breeding or transgenic approaches, a process known as biofortification. Microbial iron biofortification is a valuable approach for human being especially in developing countries where poor people cannot afford to buy expensive supplementation. Moreover, prevailing condition of Covid-19 demands a fighting immune system and iron is likely to play vital role in improving human immune system.
description: EQA - International Journal of Environmental Quality, Vol. 57 (2023)
Bloom Syndrome Helicase Promotes Meiotic Crossover Patterning and Homolog Disjunction
Creators: name: Kohl, Kathryn P.
name: McMahan, Susan
name: Hatkevich, Talia
name: Hartmann, Michaelyn A.
name: Williams, Andrew M.
name: Sekelsky, Jeff
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: In most sexually reproducing organisms, crossover formation between homologous chromosomes is necessary for proper chromosome disjunction during meiosis I. During meiotic recombination, a subset of programmed DNA double-strand breaks (DSBs) are repaired as crossovers, with the remainder becoming noncrossovers [1]. Whether a repair intermediate is designated to become a crossover is a highly regulated decision that integrates several crossover patterning processes, both along chromosome arms (interference and the centromere effect) and between chromosomes (crossover assurance) [2]. Because the mechanisms that generate crossover patterning have remained elusive for over a century, it has been difficult to assess the relationship between crossover patterning and meiotic chromosome behavior. We show here that meiotic crossover patterning is lost in Drosophila melanogaster mutants that lack the Bloom syndrome helicase. In the absence of interference and the centromere effect, crossovers are distributed more uniformly along chromosomes. Crossovers even occur on the small chromosome 4, which normally never has meiotic crossovers [3]. Regulated distribution of crossovers between chromosome pairs is also lost, resulting in an elevated frequency of homologs that do not receive a crossover, which in turn leads to elevated nondisjunction.
title: Challenging breast pathology. Don't underestimate the rare but dangerous. Mucinous breast cancer - pictorial review.
Creators: name: Couti, Claudia
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neoplasia
subject: Biopsy
subject: Ultrasound
subject: MR
subject: Mammography
subject: Oncology
subject: Breast

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To deepen the awareness over this type of invasive ductal cancer. To point out the unique characteristics of mucinous tumors. To exemplify these on every imagistic method available, in a pictorial...
National Open Access Monitor: General Consent Form
Creators: name: Ferris, Catherine
Publisher: name: Zenodo
Year: 2023
Subjects: research ethics
open access monitoring
open access
Ireland

description: This is an unsigned copy of the general consent form, which is a requirement for (non-stakeholder/non-Advisory Group) participation in the National Open Access Monitor Advisory Group under the Maynooth University research ethics procedures. A copy of the Maynooth University Ethics Approval can be found here: 10.5281/zenodo.7589178 The National Open Access Monitor Project Plan is available here: https://doi.org/10.5281/zenodo.7331431 This project is managed by IReL has received funding from Ireland’s National Open Research Forum under the NORF Open Research Fund. https://norf.ie/funding/ https://norf.ie/orf-projects-announcement/
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin
Creators: name: Woodham, Emma F.
name: Insall, Robert H.
name: Brakebusch, Cord H.
name: Paul, Nikki R.
name: Scribner, Michelle R.
name: Spence, Heather J.
name: Clark, William
name: Giampazolias, Evangelos
name: Marston, Daniel J.
name: Tyrrell, Benjamin
name: Swaminathan, Karthic
name: Hahn, Klaus M.
name: Machesky, Laura M.
name: Larue, Lionel
name: Kage, Frieda
name: Tait, Stephen W.G.
name: Hedley, Ann
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The individual molecular pathways downstream of Cdc42, Rac, and Rho GTPases are well documented, but we know surprisingly little about how these pathways are coordinated when cells move in a complex environment in vivo. In the developing embryo, melanoblasts originating from the neural crest must traverse the dermis to reach the epidermis of the skin and hair follicles. We previously established that Rac1 signals via Scar/WAVE and Arp2/3 to effect pseudopod extension and migration of melanoblasts in skin. Here we show that RhoA is redundant in the melanocyte lineage but that Cdc42 coordinates multiple motility systems independent of Rac1. Similar to Rac1 knockouts, Cdc42 null mice displayed a severe loss of pigmentation, and melanoblasts showed cell-cycle progression, migration, and cytokinesis defects. However, unlike Rac1 knockouts, Cdc42 null melanoblasts were elongated and displayed large, bulky pseudopods with dynamic actin bursts. Despite assuming an elongated shape usually associated with fast mesenchymal motility, Cdc42 knockout melanoblasts migrated slowly and inefficiently in the epidermis, with nearly static pseudopods. Although much of the basic actin machinery was intact, Cdc42 null cells lacked the ability to polarize their Golgi and coordinate motility systems for efficient movement. Loss of Cdc42 de-coupled three main systems: actin assembly via the formin FMNL2 and Arp2/3, active myosin-II localization, and integrin-based adhesion dynamics.
Adsorption of various heavy metals through dehydrated powder of two aquatic plants (Lemna minor and Eichhornia crassipes) from aqueous medium
Creators: name: Murtaza, Ghulam
name: Usman, Muhammad
name: Arif, Maham
Publisher: name: EQA - International Journal of Environmental Quality
Year: 2023

description: Different heavy metals can be eliminated by non-living or living biomass. Various aquatic plants species can be applied for the removal of metals. In this research, cadmium, copper, zinc and lead adsorption properties of Lemna minor L. and Eichhornia crassipes (Mart.) Solms were examined. This work was carried in the laboratory to ascertain the efficiency of aquatic plants Eichhornia crassipes and Lemna minor on the removal of various metals. Two plants Lemna minor and Eichhornia crassipes were obtained in a dehydrated powder type. The adsorption procedure of various metals was investigated under different pH ranges, metal ion concentration and reaction times as well as noticed the chemical composition of these plants. The results indicated that both submerged aquatic plant powders can be effectively used for heavy metal elimination under various factors. The FTIR spectra analysis showed a various functional groups in both aquatic plants, they accelerated the adsorption process.
description: EQA - International Journal of Environmental Quality, Vol. 57 (2023)
title: Imaging findings of developmental dysplasia of the hip in adults.
Creators: name: Arevalo, Noelia
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Dysplasias
subject: Education
subject: Diagnostic procedure
subject: MR
subject: CT
subject: Conventional radiography
subject: Musculoskeletal soft tissue
subject: Musculoskeletal joint

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To be familiar with the most useful radiographic measurements of the hip used to detect signs of developmental dysplasia of the hip (DDH) in adults. To discuss the role of cross-sectional imaging (including CT, MRI and MR arthrography) in the...
Resettlement, spatiotemporal dynamics of land use/cover and livelihood aspects in Chewaka district, southwestern Ethiopia
Creators: name: Abera, Alemayehu
Publisher: name: EQA - International Journal of Environmental Quality
Year: 2023

description: Ethiopia has a long tradition of resettling people from drought-prone and degraded areas to sparsely populated parts of the country. This study aimed to investigate resettlement, spatiotemporal dynamics of land use/cover and livelihood aspects in Chewaka district of Ethiopia. A combination of geospatial and socioeconomic data were utilized to attain the intended objectives. Through multistage sampling procedure, 384 households were selected from sample kebeles for household survey. Descriptive and inferential statistics along with multinomial logit model have been employed to analyze the data. The study found that resettlement has resulted in the spatiotemporal dynamics of land use/cover in Chewaka district. Rapid population growth following resettlement program, encroachment of farmland and settlement to vegetated areas, deforestation, human-induced forest fire, illegal settlement expansion, lack of land use plan, and poor management practices are driving unprecedented land use/cover change. It was also found that agriculture is the main economic activity and basis of livelihoods in the study area. Besides, resettlers pursue non/off-farm activities to generate additional income and cope with the challenges of their livelihoods. The study suggests urgent attention on improving infrastructure and social services, environment conservation, controlling illegal settlement expansions and human-induced forest fire as well as supporting resettlers to diversify their income sources for betterment of livelihoods in the area.
description: EQA - International Journal of Environmental Quality, Vol. 57 (2023)
Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development
Creators: name: Ji, Ming
name: Zhang, Yanping
name: Ren, Natalie S.X.
name: Wu, William K.K.
name: Sandler, Robert S.
name: Fargo, David C.
name: Xu, Xiaojiang
name: Lewis, DeAsia
name: Li, Xiangchun
name: Li, Xiaoling
name: Busch, Evan L.
name: Huang, Weichun
name: Keku, Temitope O.
name: Jin, Aiwen
name: Tokar, Erik J.
name: Li, Leping
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: SIRT1, the most conserved mammalian NAD+-dependent protein deacetylase, plays a vital role in the regulation of metabolism, stress responses, and genome stability. However, the role of SIRT1 in the multi-step process leading to transformation and/or tumorigenesis, as either a tumor suppressor or tumor promoter, is complex and maybe dependent upon the context in which SIRT1 activity is altered, and the role of SIRT1 in tumor metabolism is unknown. Here we demonstrate that SIRT1 dose-dependently regulates cellular glutamine metabolism and apoptosis, which in turn differentially impact cell proliferation and cancer development. Heterozygous deletion of Sirt1 induces c-Myc expression, enhancing glutamine metabolism and subsequent proliferation, autophagy, stress resistance and cancer formation. In contrast, homozygous deletion of Sirt1 triggers cellular apoptotic pathways, increases cell death, diminishes autophagy, and reduces cancer formation. Consistent with the observed dose-dependence in cells, intestine-specific Sirt1 heterozygous mice have enhanced intestinal tumor formation, whereas intestine-specific Sirt1 homozygous knockout mice have reduced development of colon cancer. Furthermore, SIRT1 reduction but not deletion is associated with human colorectal tumors, and colorectal cancer patients with low protein expression of SIRT1 have a poor prognosis. Taken together, our findings indicate that the dose-dependent regulation of tumor metabolism and possibly apoptosis by SIRT1 mechanistically contributes to the observed dual roles of SIRT1 in tumorigenesis. Our study highlights the importance of maintenance of a suitable SIRT1 dosage for metabolic and tissue homeostasis, which will have important implications in SIRT1 small molecule activators/inhibitors based therapeutic strategies for cancers.
Corrected constraints on big bang nucleosynthesis in a modified gravity model of $f(R) \propto R^n$
Creators: name: Kusakabe, Motohiko
name: Koh, Seoktae
name: Kim, K. S.
name: Cheoun, Myung-Ki
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Big bang nucleosynthesis in a modified gravity model of $f(R)\propto R^n$ is investigated. The only free parameter of the model is a power-law index $n$. We find cosmological solutions in a parameter region of $1< n \leq (4+\sqrt{6})/5$. We calculate abundances of $^4$He, D, $^3$He, $^7$Li, and $^6$Li during big bang nucleosynthesis. We compare the results with the latest observational data. It is then found that the power-law index is constrained to be $(n-1)=(-0.86\pm 1.19)\times 10^{-4}$ (95 % C.L.) mainly from observations of deuterium abundance as well as $^4$He abundance.
description: 6 pages, 2 figures, Published by APS at http://journals.aps.org/prd/abstract/10.1103/PhysRevD.91.104023
title: Evaluation of Cervical Lymph Nodes in malignant and non-malignant disease: ultrasonography combined with fine-needle aspiration cytology
Creators: name: Pasetto, Stefano
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Pathology
subject: Foreign bodies
subject: Acute
subject: Puncture
subject: Ultrasound
subject: Lymph nodes
subject: Interventional non-vascular

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The objective of this poster is to show the role of high frequency ultrasound and color Doppler imaging in the diagnostic evaluation of patients with cervical lymphadenopathy. Ultrasound is a useful imaging modality in evaluation of cervical...
Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk
Creators: name: Bennett, Brian J.
name: Meyer, Katie A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Over the past decade, the gut microbiome has emerged as a novel and largely untapped source of variability for metabolic and cardiovascular disease risk, including diabetes. Animal and human studies support several possible pathways through which the gut microbiome may impact health, including the production of health-related metabolites from dietary sources. Diet is considered important to shaping the gut microbiota; in addition, gut microbiota influence the metabolism of many dietary components. In the present paper, we address the distinction between compositional and functional analysis of the gut microbiota. We focus on literature that highlights the value of moving beyond surveys of microbial composition to measuring gut microbial functioning to delineate mechanisms related to the interplay between diet and gut microbiota in cardiometabolic health.
title: Radiologic evaluation of the finger: ultrasound pathologic findings with MR and CT correlation
Creators: name: Pasetto, Stefano
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Tissue characterisation
subject: Pathology
subject: Foreign bodies
subject: Education
subject: Ultrasound
subject: MR
subject: CT
subject: Musculoskeletal soft tissue
subject: Musculoskeletal joint

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: US is currently one of the main imaging tools used for evaluating the superficial structures of the finger. The aim of this poster is to review basic anatomy andscanning techniques, to illustrate theultrasound appearance of the normal fingers's...
The Hopf type theorem for equivariant gradient local maps
Creators: name: Bartłomiejczyk, Piotr
name: Nowak-Przygodzki, Piotr
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics

description: We construct a degree-type otopy invariant for equivariant gradient local maps in the case of a real finite dimensional orthogonal representation of a compact Lie group. We prove that the invariant establishes a bijection between the set of equivariant gradient otopy classes and the direct sum of countably many copies of $\mathbb{Z}$.
description: 18 pages, 5 figures, new figures, added references, corrected typos, extra explanations
The Promise and Challenge of Therapeutic MicroRNA Silencing in Diabetes and Metabolic Diseases
Creators: name: Sethupathy, Praveen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: MicroRNAs (miRNAs) are small, non-coding, RNA molecules that regulate gene expression. They have a long evolutionary history and are found in plants, viruses, and animals. Although initially discovered in 1993 in Caenorhabditis elegans, they were not appreciated as widespread and abundant gene regulators until the early 2000s. Studies in the last decade have found that miRNAs confer phenotypic robustness in the face of environmental perturbation, may serve as diagnostic and prognostic indicators of disease, underlie the pathobiology of a wide array of complex disorders, and represent compelling therapeutic targets. Pre-clinical studies in animal models have demonstrated that pharmacologic manipulation of miRNAs, mostly in the liver, can modulate metabolic phenotypes and even reverse the course of insulin resistance and diabetes. There is cautious optimism in the field about miRNA-based therapies for diabetes, several of which are already in various stages of clinical trials. This review will highlight both the promise and the most pressing challenges of therapeutic miRNA silencing in diabetes and related conditions.
Self-organised Limit-Cycles, Chaos and Phase-Slippage with a Superfluid inside an Optical Resonator
Creators: name: Piazza, Francesco
name: Ritsch, Helmut
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study dynamical phases of a driven Bose-Einstein condensate coupled to the light field of a high-Q optical cavity. For high field seeking atoms at red detuning the system is known to show a transition from a spatially homogeneous steady-state to a self-organized regular lattice exhibiting super-radiant scattering into the cavity. For blue atom pump detuning the particles are repelled from the maxima of the light-induced optical potential suppressing scattering. We show that this generates a new dynamical instability of the self-ordered phase, leading to the appearance of self-ordered stable limit-cycles characterized by large amplitude self-sustained oscillations of both the condensate density and cavity field. The limit-cycles evolve into chaotic behavior by period doubling. Large amplitude oscillations of the condensate are accompanied by phase-slippage through soliton nucleation at a rate which increases by orders of magnitude in the chaotic regime. Different from a superfluid in a closed setup, this driven dissipative superfluid is not destroyed by the proliferation of solitons since kinetic energy is removed through cavity losses.
description: 4 figures
Simulation of an extreme flood event in a Peruvian Andean basin. A first approach for implementing the WRF-Hydro model
Creators: name: Callan, Nadia
name: Rau, Pedro
name: Castillon, Fiorela
name: Lavado, Waldo
Publisher: name: figshare
Year: 2023
Subjects: Water resources engineering
Surface water hydrology

description: Proceedings of the 3rd IAHR Young Professionals Congress. Online. 28 November - 2 December 2022
title: Victorino José dos Santos
Creators: name: Osório da Silva, Sandra
Publisher: name: CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa
Year: 2022

description: Entrada biográfica sobre Victorino José dos Santos, na plataforma eViterbo
description: Silva, Sandra Osório da. 2022. Victorino José dos Santos in eViterbo. CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa. eISBN: 978-989-8492-77-7
Fragmentation functions of $g\rightarrow η_c (^{1}S_0)$ and $g\rightarrow J/ψ(^{3}S_1)$ considering the role of heavy quarkonium spin
Creators: name: Nejad, S. M. Moosavi
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The production of heavy quarkonia is a powerful tool to test our understanding of strong interaction dynamics. It is well-known that the dominant production mechanism for heavy quarkonia with large transverse momentum is fragmentation. In this work we, analytically, calculate the QCD leading order contribution to the process-independent fragmentation functions (FFs) for a gluon to split into the vector ($J/ψ$) and pseudoscalar ($η_c$) $S$-wave charmonium states. The analyses of this paper differ in which we present, for the first time, an analytical form of the $g\rightarrow J/ψ$ FF using a different approach (Suzuki's model) in comparison with other results presented in literatures, where the Braaten's scheme was used and the two-dimensional integrals were presented for the gluon FFs which must be evaluated numerically. The universal fragmentation probability for the $g\rightarrow J/ψ$ is about $10^{-6}$ which is in good consistency with the result obtained in the Braaten's model.
Absolute order in general linear groups
Creators: name: Huang, Jia
name: Lewis, Joel Brewster
name: Reiner, Victor
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 20G40, 05E10, 20C33

description: This paper studies a partial order on the general linear group GL(V) called the absolute order, derived from viewing GL(V) as a group generated by reflections, that is, elements whose fixed space has codimension one. The absolute order on GL(V) is shown to have two equivalent descriptions, one via additivity of length for factorizations into reflections, the other via additivity of fixed space codimensions. Other general properties of the order are derived, including self-duality of its intervals. Working over a finite field F_q, it is shown via a complex character computation that the poset interval from the identity to a Singer cycle (or any regular elliptic element) in GL_n(F_q) has a strikingly simple formula for the number of chains passing through a prescribed set of ranks.
description: 26 pages. v2: Minor edits; Question 6.3 and some references added
Arsenic Exposure and Type 2 Diabetes: MicroRNAs as Mechanistic Links?
Creators: name: Beck, Rowan
name: Sethupathy, Praveen
name: Styblo, Miroslav
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: PURPOSE OF REVIEW: The goal of this review is to delineate the following: (1) the primary means of inorganic arsenic (iAs) exposure for human populations, (2) the adverse public health outcomes associated with chronic iAs exposure, (3) the pathophysiological connection between arsenic and type 2 diabetes (T2D), and (4) the incipient evidence for microRNAs as candidate mechanistic links between iAs exposure and T2D.

RECENT FINDINGS: Exposure to iAs in animal models has been associated with the dysfunction of several different cell types and tissues, including liver and pancreatic islets. Many microRNAs that have been identified as responsive to iAs exposure under in vitro and/or in vivo conditions have also been shown in independent studies to regulate processes that underlie T2D etiology, such as glucose-stimulated insulin secretion from pancreatic beta cells. Defects in insulin secretion could be, in part, associated with aberrant microRNA expression and activity. Additional in vivo studies need to be performed with standardized concentrations and durations of arsenic exposure in order to evaluate rigorously microRNAs as molecular drivers of iAs-associated diabetes.