cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Health and Wellbeing of Female Street Sex Workers
Creators: name: Elliott, Nalishebo
Publisher: name: UH Research Archive
Year: 2017
Subjects: Health and wellbeing
street sex workers
prostitution
health needs
lived experience
mental health
social inequality
physical health
social health

description: Previous research on female street sex workers (FSSWs) has primarily concentrated on the stigmatisation of women’s involvement in the sex industry particularly with reference to the spread of HIV/AIDS. The response of the criminal justice system to the regulation of the illegal aspects of women’s engagement in street sex work has also been criticised. However, the impact of street sex work on the health and wellbeing of these women requires further research. The aim of this study was to explore the perceptions and needs of female street sex workers in relation to their own health and wellbeing. The study used a qualitative mixed methods approach that included analysis of three sets of data: visual data, secondary data and primary data. There were 10 FSSWs recruited for the primary data sample. The epistemological position underpinning this study is social constructivism and a feminist paradigm has informed the conduct of the research process and data analysis. The theoretical application of Bourdieu’s framework of habitus, capital and field has provided the lens through which to explore the socially constructed experiences of FSSWs health and wellbeing. Findings from this study revealed that FSSWs experienced poor physical, mental and social health and wellbeing. They faced limited life choices and often felt discriminated against by the agencies and institutions that should have offered support. The women spoke of their personal histories especially traumatic life events in childhood consisting of sexual abuse, neglect, loss, rejection as well as intimate partner violence in adult life. The loss of their children to social services, housing difficulties and addiction to alcohol and crack cocaine were also significant in contributing to social exclusion and their multiple positions of vulnerability. This study contributes to the body of work on women’s health and wellbeing. In particular, it adds to our understanding of the lived experiences of women involved in street sex work. A key public health priority should be the development of policies and systems to provide quality services to support the health, safety and wellbeing of FSSWs.
Direct syntheses of a series of cucurbit[n]uril-anchored polyacrylamides
Creators: name: Xiao, Bo
name: Fan, Ying
name: Ji, Ning-Ning
name: Cheng, Xiao-Jie
name: Wang, Chuan-Zeng
name: Zhou, Jia-Jia
name: Xue, Sai-Feng
name: Tao, Zhu
name: Zhu, Qian-Jiang
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Biochemistry
subject: Biophysics

description: Using the one-pot, direct strategy reported by Su and co-workers, we have synthesised a series of cucurbit[n]urils (Q[n], n = 5–8) and alkyl-substituted cucurbit[6]urils (SQ[6]s) anchored on polymers. Acrylamide, as a typical monomer, was used to synthesise a series of Q[n]s (n = 5–8) and SQ[6]-anchored polyacrylamides (PAMs) using a persulfate salt as initiator and oxidant. The Q[n]s (n = 5–8) and SQ[6]-anchored PAM samples have been characterised by 1H NMR, 1H NMR titrations of probe guests, Fourier-transform infrared and thermogravimetric analyser. The results confirmed that PAM chains had been successfully grafted on the back of the Q[n]s (n = 5–8) and SQ[6]s through an in situ radical polymerisation approach. It was further confirmed that the hydrophobic cavities of the Q[n]s on the polymers were still freely accessible. This synthetic approach may be extended to a variety of Q[n]s that are difficult to functionalise.
The Experiences of Reflective Practice Groups as Part of Doctoral Clinical Psychology Training: an IPA Study
Creators: name: Lyons, Amy
Publisher: name: UH Research Archive
Year: 2017
Subjects: Reflective Practice
Reflection
Clinical Psychology
Clinical Psychology training
Reflective learning

description: Despite many Clinical Psychology training programmes utilizing reflective practice groups as part of clinical training, there remains little research examining the experiences of such groups from a trainee perspective. However, it remains the preferred method of developing reflective practice skills during training. This research used interviews and Interpretative Phenomenological Analysis to explore the experiences of attending reflective practice groups as part of doctoral Clinical Psychology training. A purposive sample of eight participants were recruited for a single, semi-structured interview. The interviews were audio-recoded, transcribed and analysed by the researcher. Five superordinate themes were constructed: ‘the process: there were so many layers’, ‘the impact: an ongoing process’, ‘the facilitator: a presence who was not always present’, ‘commitment: I hated it, but I still went’ and ‘getting through it: finding ways to cope’. Nineteen corresponding subordinate themes were constructed from the data. The research findings illustrate the varied and complex experiences of the participants. Whilst the experience was often difficult, participants appeared committed to attending and sought out ways in which to navigate the experience. The results are conceptualised in terms of existing psychological theory and literature. A critique of the research and suggestions for future studies are offered, which include exploring the views of the facilitators of such groups and comparing how groups are utilized within different training institutions. Recommendations are made related to the development of future reflective practice groups, which include recommendations related to the style of facilitation and the frequency and size of the group.
The Role of the Boundary Layer and the Associated Physical Processes During Hot Days and Heatwaves in Southeastern Australia
Creators: name: Huang, Qinuo
Publisher: name: Monash University
Year: 2025
Subjects: classificationCode: 370105
subject: Atmospheric dynamics

description: This thesis explores what happens in the atmospheric boundary layer (from the surface to approximately 3 km) and how these processes contribute to heatwaves in southeastern Australia from an observational and modelling perspective. It is found that a northwesterly nocturnal jet transports warm air into the hot day region and the initially high nighttime temperatures resulting from subsidence associated with an upper-level high pressure system determine a hot day. Single hot days can turn into heatwaves when the upper-level high pressure system moves slowly over the region.
The Flight from History: From H G Wells to Doctor Who – and Back Again
Creators: name: Charles, Alec
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200599 Literary Studies not elsewhere classified
subject: FOS: Languages and literature

description: This paper examines how, in the wake of 9/11, BBC Television s Doctor Who has symbolically explored that catastrophe and the efforts to con-struct a new world order in its aftermath. In doing so, it witnesses parallels with the apocalyptic and utopian visions of the programme s own greatest literary influence, the seminal science fiction of H G Wells.
On Failure and Revolution in Utopian Fiction and Science Fiction of the 1960s and 1970s
Creators: name: Jorgensen, Darren
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200599 Literary Studies not elsewhere classified
subject: FOS: Languages and literature

description: Ursula Le Guin’s The Dispossessed (1974) was a bestselling novel of its time, and remains a classic work of contemporary utopian fiction. Despite its successes, utopian scholar Tom Moylan describes it as a flawed example of his own model of a critical utopian form particular to the 1970s. He considers Joanna Russ’s The Female Man (1975), Samuel Delany’s Triton (1976) and Marge Piercy’s Woman on the Edge of Time (1979) to be more adequately critical, as they call into question the stasis of a passively perfect society with an engaged, open, critical utopia. This kind of self-reflexivity toward the closures of the utopian imagination was necessitated in the 1970s by the totalitarian tendencies of the twentieth century, as Nazi Germany, Stalin’s Soviet Union, Mao’s China and corporate America pro-claimed their utopian credentials but with little of the happiness and liberty that was supposed to accompany utopia’s realisation. The experimental, open-ended play of Piercy, Russ and Delany responds to this historical situation by dialogically interrogating the narrative conventions of closure, to push generic boundaries and negate the utopian claims of historical states.
Synthesis, crystal structure, and application as a Ag+ chemodosimeter of phosphorescent iridium complexes
Creators: name: Xue, Fengfeng
name: Lu, Yang
name: Zhou, Zhiguo
name: Zhang, Chen
name: Fang, Shichao
name: Yang, Hong
name: Yang, Shiping
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The syntheses and crystal structures of two iridium complexes, (dfppy)2IrPyCl (1) and [(dfppy)2Ir(Py)2]PF6 (2), are reported. 1 can selectively detect Ag+ with UV–vis absorption and emission spectra. In the presence of Ag+, the obvious decrease of the luminescence intensity at 476 nm was observed, which could be monitored by the naked eyes. The phosphorescence quantum yield decreases from 0.024 to 0.012. No obvious changes of the luminescence intensity were observed upon addition of a large excess of other transition metal ions. Due to the strong interaction between chloride and Ag+, the special chemical reaction induced by Ag+ is responsible for the significant change of absorption and luminescence spectra.
Synthesis, crystal structure and application as a Ag+ chemodosimeter of phosphorescent iridium complexes
Creators: name: Xue, Fengfeng
name: Lu, Yang
name: Zhou, Zhiguo
name: Zhang, Chen
name: Fang, Shichao
name: Yang, Hong
name: Yang, Shiping
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: The syntheses and crystal structures of two iridium complexes, (dfppy)2IrPyCl (1) and [(dfppy)2Ir(Py)2]PF6 (2), are reported. 1 can selectively detect Ag+ with UV-Vis absorption and emission spectra. In the presence of Ag+, the obvious decrease of the luminescence intensity at 476 nm was observed, which could be monitored by the naked eyes. The phosphorescence quantum yield decreases from 0.024 to 0.012. No obvious changes of the luminescence intensity were observed upon addition of a large excess of other transition metal ions. Due to the strong interaction between chloride and Ag+, the special chemical reaction induced by Ag+ is responsible for the significant change of absorption and luminescence spectra.
Responses of People With Physical Health Conditions to Changes in Disability Benefits: A Grounded Theory Study
Creators: name: Saffer, Jessica
Publisher: name: UH Research Archive
Year: 2017
Subjects: Disability benefit
Physical health
Welfare reform
Mental health
Austerity
Grounded theory

description: There is a dearth of literature on the experiences of people with physical health conditions who make disability benefit claims and live as a benefit claimant, particularly since the recent and ongoing changes to the benefits system in the UK. This research aimed to explore the social processes that impact on people with a physical health condition who have experienced a loss of or change in disability benefits, particularly in relation to their identity and their relationships with society. In-depth interviews were conducted with fifteen people with physical health conditions or disabilities. Data was analysed using Grounded Theory methods and a theoretical model was co-constructed. Participants experienced the benefits system as dehumanising, and felt that they lived in a judgemental society, where they were perceived as ‘scroungers’ and faced discrimination from others. These experiences negatively affected their mental and physical health and wellbeing. Participants often internalised the stigma surrounding disability benefit claimants and they attempted to resist this in order to maintain a preferred sense of self. The findings demonstrate the significant impact of benefit changes on wellbeing and identity. The research highlights important implications for Psychologists, as well as staff in healthcare, the benefits system, and government.
Development of Sensitisation Resistant 5XXX series Aluminium Alloys
Creators: name: Hanning Shi
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: The study of 5xxx aluminium alloys based on the Al-Mg-Mn system, particularly for the prevention and reparation after sensitisation, has gained new attention in the past decade. AA 5083 alloys that exist on more than 200 commercial vessels as well as some navy vessels are reported to be susceptible to intergranular corrosion (IGC). However, compared with the significant efforts put into understanding and quantifying the sensitisation of 5xxx alloys, limited previous research has been performed to develop 5xxx alloys with better inherent resistance to IGC arising from sensitisation. This work will present an exploration towards the development of corrosion and sensitisation resistant 5xxx series. To achieve this, alloying additions of manganese were manipulated in amount, as well as alloying additions of silver, zinc and strontium were added to AA5083(Al-Mg-Mn) at low, medium and high levels, followed by a range of electrochemical tests and characterisation methods. Some major findings were made from the project, including that sensitisation behaviour was found to be largely independent of manganese elemental content over the expected range of its concentration in commercial 5083 alloys, while silver and zinc in small amounts improved nobility.
Formas emergentes de quotidianização da festa
Creators: name: Lages, Mário Ferreira
Publisher: name: Comunicação & Cultura
Year: 2010

description: O presente texto pretende entender alguns fenómenos sociais emergentes – fast feasts, subway parties, flash mobs, zombie walks, free hugs, quase todos surgidos em países de língua inglesa, mas presentes em todas as sociedades – no quadro de uma teoria da quotidianização da festa, segundo a qual, as classes urbanas mais afluentes, libertas das tarefas da produção de bens materiais, na sua função de agentes da transformação cultural, não se cansam de inventar novas formas festivas de lazer. Na impossibilidade de dar conta de todos os factos e circunstâncias que favoreceram o seu desenvolvimento, privilegiam-se os eventos de maior impacto e visibilidade sociais, muitas vezes porque estranhos e provocatórios. Tenta-se igualmente perceber em que medida alguns destes fenómenos começam a ritualizar-se, o que permite entrever o modo como os comportamentos se codificam e as culturas se transformam e estruturam.
description: Comunicação & Cultura, n. 10 (2010): A festa
Entrevista a Richard Grusin
Creators: name: Gonçalves, Diana
Publisher: name: Comunicação & Cultura
Year: 2010

description: Richard Grusin é director do Center for 21st Century Studies, na Universidade de Wisconsin-Milwaukee, onde lecciona Estudos de Cinema e Media, Nova Teoria dos Media e Estudos sobre a Modernidade. É co-autor de Remediation: Understanding New Media. É também autor do recém-publicado livro Premediation: Affect and Mediality in America after 9/11. A entrevista aqui transcrita decorreu em Lisboa, durante a conferência internacional sobre o tema «The Arts of Mediation», organizada pelo Centro de Estudos de Comunicação e Cultura (CECC) da Faculdade de Ciências Humanas da Universidade Católica Portuguesa, em Março de 2010.
description: Comunicação & Cultura, n. 10 (2010): A festa
Ambiguidades da secularização entre modernidade e pós-modernidade
Creators: name: Duque, João Manuel
Publisher: name: Comunicação & Cultura
Year: 2011

description: O artigo parte da consideração de uma espécie de dialéctica, inerente à modernidade, no que respeita à relação com o sagrado, que acabou por implicar deslocações deste para âmbitos considerados «profanos». A modernidade tardia e o denominado regresso do religioso apenas vieram revelar melhor essa dialéctica. Daí resulta uma possível leitura da secularização moderna como sacralização do «secular», enquanto âmbito de um novo absoluto. Em contrapartida, a tradição teológica da secularização pode ser entendida como crítica relativização do secular, em permanente processo de «desdivinização», ao que parece corresponder, como contrapartida estranha, um modo de neo-sacralização com base no religioso não teológico – numa religião sem Deus. É neste dinamismo ambivalente que se pode falar dos elementos que marcaram as ambiguidades da secularização moderna: a absolutização da natureza, a recuperação de uma religião civil, a divinização da razão científica, entre muitas outras versões.
description: Comunicação & Cultura, n. 11 (2011): Sagrado e modernidade
René Girard's apocalyptic modernity
Creators: name: Doran, Robert
Publisher: name: Comunicação & Cultura
Year: 2011

description: This essay examines how René Girard’s most recent book, Achever Clausewitz (2007), expands on Girard’s theory of the sacred to include a more specific and concrete notion of the apocalypse as a historically conditioned concept. In particular, I argue that the idea of “total war” (the kind of war engendered by mass conscription) is crucial to Girard’s critique of Clausewitz, which consists in pointing out the irreconcilability between Clausewitz’s famous formula “war is politics by other means” (i.e., war is contained or limited by politics) and Clausewitz’s idea of the “escalation to extremes” (uncontainable violence). I show how this reading of Clausewitz allows Girard to deconstruct the opposition between archaic (irrational) and modern (rational) violence that defines Enlightenment hope. Finally, I ask if the advent of post-9/11 terrorism, which is a form of total war, might not lead us to rethink the role of international institutions (such as the International Criminal Court) in stemming the explosive potential of non-localized violence.
description: Comunicação & Cultura, n. 11 (2011): Sagrado e modernidade
Yoked Sequences
Creators: name: Tangen, Jason M
name: Thompson, Matthew B
name: Vokey, John R
name: Searston, Rachel A.
Publisher: name: OSF Registries
Year: 2018

description: This component contains the full set of 146 pregenerated yoked participant sequences as unique .txt files that are read into the custom experiment presentation program: Scramble-Experiment01-SequencePresentationScript-RachelASearston.livecode. The "randomised" sequences are the 146 sequences as to be presented to participants in the experiment. The "sorted" sequences are the exact same set of 146 sequences, but sorted by trial type (i.e., match, mismatch).
The syntheses, crystal structures, and characterizations of two MnII/III-sandwiching polyoxometalate complexes based on [α-SeW9O33]8− units
Creators: name: Zhao, Yue
name: Xu, Kai-Cheng
name: Song, Ying
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Two sandwich-type polyoxometalates (POM) based on [α-SeW9O33]8− building blocks, K8[{MnII(H2O)}2(WO)(SeW9O33)2]·12H2O (1) and K6[{MnIII(H2O)}2(WO)(SeW9O33)2]·18H2O (2), have been synthesized and characterized by elemental analyses, IR, diffuse reflectance UV–vis-NIR spectra, TG, X-ray photoelectron spectroscopy, and single-crystal X-ray diffraction. Electrochemical properties and photocatalytic activities have also been investigated. Single-crystal X-ray diffraction analysis shows that the polyoxoanions of 1 and 2 have similar sandwich structures composed of [α-SeW9O33]8− units except for different oxidation states of Mn centers (II for 1, III for 2). Compound 2 is the first high-valent trinuclear-manganese (III)-substituted [α-SeW9O33]8−-based POM. Cyclic voltammograms of 1 and 2 show irreversible redox processes for Mn2+ and Mn3+, respectively. Compound 2 has better photocatalytic properties with photocatalytic degradation of Rhodamine-B (RhB) compared to 1.
Sobre a origem e a tradição do Feindbild Islão
Creators: name: Benz, Wolfgang
Publisher: name: Comunicação & Cultura
Year: 2011

description: Tomando como ponto de partida a publicação do livro de Thilo Sarrazin Deutschland schafft sich ab. Wie wir unser Land aufs Spiel setzen («A Alemanha está a anular‑se. Como arriscamos o futuro do nosso país»), o presente texto apresenta uma reflexão sobre a xenofobia e o racismo cultural na Europa contemporânea. O autor demonstra as raízes seculares do Feindbild Islão e como este foi construído ao longo dos séculos, invocando um mundo maniqueísta e aliviando frustrações políticas e sociais. Benz demonstra que hoje, tal como no passado, o discurso xenófobo, em crescimento na Alemanha e na Europa em geral, revela acima de tudo um profundo desconhecimento sobre o Islão.
description: Comunicação & Cultura, n. 11 (2011): Sagrado e modernidade
MOESM1 of Enhanced biosynthesis of arbutin by engineering shikimate pathway in Pseudomonas chlororaphis P3
Creators: name: Wang, Songwei
name: Fu, Cong
name: Bilal, Muhammad
name: Hu, Hongbo
name: Wang, Wei
name: Zhang, Xuehong
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 1. Additional Figure S1â S4 and Tables S1â S2. Table S1. Main primers designed and used in this study. Table S2. The corresponding accession numbers of nucleotide sequence data. Figure S1. Identification of arbutin by LC-MC analyses. Figure S2. The change of pH value of P3-Ar5 cultures in KBG medium. Figure S3. The arbutin titer of the plasmid-free strain P3-Ar5 after culturing for 1â 30 generations in KBG medium.
O diálogo ecuménico enquanto diálogo com o «outro»
Creators: name: Soares, Fernando Da Luz
Publisher: name: Comunicação & Cultura
Year: 2011

description: Nos dois primeiros pontos deste artigo, explicita-se a tensão sentida, desde o início do Movimento Ecuménico, no entendimento da unidade cristã como, por um lado, uma mera condição prática para fazer a missão, a conquista de prosélitos, e, por outro, o diálogo entre as Igrejas, atitude de descoberta para chegar a uma Igreja unida. Para isso, analisam-se numa sucinta memória histórica alguns acontecimentos que marcaram o percurso do ecumenismo, desde a Conferência Missionária Mundial, realizada em 1910 em Edimburgo, considerada hoje o início do Movimento, até ao Vaticano II e ao seu decreto «O Ecumenismo». Referem-se também as posições de alguns ilustres teólogos, católicos e protestantes, relativamente ao exercício do ecumenismo como diálogo que leve a conhecer a realidade das diversas Igrejas e o valor da diferença. No terceiro ponto deste artigo, aborda-se a questão do «outro» e da alteridade. No quarto, liga-se esta questão às alterações sociológicas que se têm verificado na Europa Ocidental, nos últimos setenta anos, com os consequentes problemas para o diálogo ecuménico num contexto de pluralismo religioso. Apresentam-se em seguida duas histórias bíblicas de convivência em diversidade cultural: o caso de Abraão, no Antigo Testamento, e o Pentecostes, no Novo Testamento. Conclui-se, por fim, que a unidade cristã exige uma transformação na perspectiva de vida das Igrejas cristãs, que lhes permita uma atitude de verdadeira compreensão da diferença, centrada no mistério dos outros e no mistério de Deus.
description: Comunicação & Cultura, n. 11 (2011): Sagrado e modernidade
The syntheses, crystal structures and characterizations of two MnII/III-sandwiching polyoxometalate complexes based on [α-SeW9O33]8− units
Creators: name: Zhao, Yue
name: Xu, Kai-Cheng
name: Song, Ying
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: Two sandwhich-type polyoxometalates based on [α-SeW9O33]8− building blocks, K8[{MnII(H2O)}2(WO)(SeW9O33)2]·12H2O (1) and K6[{MnIII(H2O)}2(WO)(SeW9O33)2]·18H2O (2), have been synthesized and characterized by elemental analyses, IR, diffuse reflectance UV-vis-NIR spectra, TG, X-ray photoelectron spectroscopy (XPS) and single-crystal X-ray diffraction. Electrochemical properties and photocatalytic activities have also been investigated. Single crystal X-ray diffraction analysis shows that the polyoxoanions of 1 and 2 have similar sandwich structures composed of [α-SeW9O33]8− units except for different oxidation states of Mn centers (II for 1, III for 2). Compound 2 is the first high-valent trinuclear-manganese (III)-substituted [α-SeW9O33]8−-based polyoxometalate. Cyclic voltammograms of 1 and 2 show irreversible redox processes for Mn2+ and Mn3+, respectively. Compound 2 has better photocatalytic properties with photocatalytic degradation of rhodamine-B (RhB) compared to 1.
Deus na escola pública
Creators: name: Mucznik, Esther
Publisher: name: Comunicação & Cultura
Year: 2011

description: A modernidade – associada ao Iluminismo europeu – pôs em questão a importância de quase tudo o que está associado à palavra «religião». O novo paradigma era a ciência, condição absoluta do progresso social e humano, capaz por si só de forjar um mundo melhor. De forma dramática, o século xx veio desmentir esta ilusão e fazer-nos entender que as grandes religiões devem fazer parte do espaço e do diálogo público e, em primeiro lugar, do ensino público, mesmo num Estado laico. Os manuais são um dos principais veículos do programa escolar. São pois um reflexo privilegiado não só do lugar do fenómeno religioso no sistema de ensino, mas sobretudo das relações entre a religião e a sociedade. O texto apresentado é uma síntese da investigação realizada em 2007 para a Comissão de Liberdade Religiosa que teve como objectivo o conhecimento da forma como as religiões são abordadas nos manuais escolares.
description: Comunicação & Cultura, n. 11 (2011): Sagrado e modernidade
Hypolipidaemic and antioxidant properties of ethanol extract from Flos populi
Creators: name: Zhao, Yan
name: Tang, Guosheng
name: Cai, Enbo
name: Liu, Shuangli
name: Zhang, Lianxue
name: Wang, Shijie
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Uncategorised

description: This study was undertaken to evaluate antihyperlipidaemic and in vitro antioxidant activity of ethanolic extract of Flos populi (EFP). The results demonstrated that EFP contains 78.5% flavonoids and 10.4% phenolics, and it exhibited free radical-scavenging activity on 2,2-diphenyl-picrylhydrazyl (IC50 36.40 ± 0.62 μg/mL) and high reducing power (EC50 206.32 ± 1.6l μg/mL) under in vitro chemical assays. And irrespective of prophylactic administration or remedial administration, in high fat diet-induced hyperlipidaemic mice, oral treatment with EFP produced a decrease in the levels of serum total cholesterol, triglycerides, low-density lipoprotein-cholesterol and increase in high-density lipoprotein-cholesterol. In a word, in high fat diet-fed hyperlipidaemic mice, EFP (100, 200 and 400 mg/kg) significantly altered the plasma lipid levels to near normal. These results support a potential effect of EFP in cardiovascular disease.
Card shuffles and nucleotide sequences
Creators: name: Highmore, Roger
Publisher: name: figshare
Year: 2017
Subjects: subject: 60112 Structural Biology (incl. Macromolecular Modelling)
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 10104 Combinatorics and Discrete Mathematics (excl. Physical Combinatorics)
subject: FOS: Mathematics
subject: 10202 Biological Mathematics

description: We examine whether some ideas from the mathematics of card shuffles can usefully be applied to sequences of nucleotides in molecules. If certain orderings exist or can be achieved in sequences of nucleotides, they would help molecules bind to exact, unique locations.
Facile Method for the Large-Scale Synthesis of 6,7,4′-Trihydroxyisoflavanone
Creators: name: Liu, Jing
name: Yang, Zhangyou
name: Luo, Shenglin
name: Hao, Yuhui
name: Ren, Jiong
name: Su, Yongping
name: Wang, Weidong
name: Li, Rong
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: 6,7,4′-Trihydroxyisoflavanone, the main source of which is extracted from soybeans, has been found to have diverse significant bioactivities. A large-scale, cost-effective, and facile chemical synthesis of 6,7,4′-trihydroxyisoflavanone is presented herein. Its synthesis is characterized by three steps with an overall yield of 71% and a purity or more than 99.0%. This reaction can be scaled up to multikilogram quantities, providing a solid basis for its further bioactivity studies and drug development. With this same method, 6,7,3′,4′-tetrahydroxyisoflavanone, an analog of 6,7,4′-trihydroxyisoflavanone, also can be largely prepared, indicating this modified synthetic method is potentially available for large-scale synthesis of a broad range of multihydroxyl isoflavanones.
A Facile Method for the Large-Scale Synthesis of 6,7,4′-trihydroxyisoflavanone
Creators: name: Liu, Jing
name: Yang, Zhangyou
name: Luo, Shenglin
name: Hao, Yuhui
name: Ren, Jiong
name: Su, Yongping
name: Wang, Weidong
name: Li, Rong
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: 6,7,4′-Trihydroxyisoflavanone, the main source of which is extracted from soybeans, has been found to have diverse significant bioactivities. A large-scale, cost-effective and facile chemical synthesis of 6,7,4′-trihydroxyisoflavanone is presented herein. Its synthesis is characterised by three steps with an overall yield of 71% and a purity over 99.0%. This reaction can be scaled up to multi-kilogram quantities, providing a solid basis for its further bioactivity studies and drug development. With this same method, 6,7,3′,4′-tetrahydroxyisoflavanone, an analog of 6,7,4′-trihydroxyisoflavanone also can be largely prepared, indicating this modified synthetic method potentially available for large-scale synthesis of a broad range of multi-hydroxyl isoflavanones.
Cue additivity and adaptivity in predictive processing
Creators: name: Henry, Nick
name: Hopp, Holger
name: Jackson, Carrie N.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: This study tests how the parser adapts to input by considering how multiple redundant cues are integrated in predictive processing. We employ the visual world paradigm to investigate whether German native speakers use case and prosody together to anticipate post-verbal arguments. In Experiment 1, participants heard subject-first and object-first sentences containing either case and prosodic cues or only case cues in a single mixed block. In Experiments 2 and 3, sentences were presented in separate blocks, such that participants heard sentences with prosodic cues in either Block 1 (Experiment 3) or Block 2 (Experiment 2). The results show that participants used prosodic and case-marking cues additively to anticipate post-verbal arguments. Additive effects varied according to the distribution of the cues and their order of presentation. We conclude that the presence of multiple redundant cues facilitates sentence processing and that the parser adapts to the utility of cues based on their availability.
Characterisation of a Novel Flexing Diffusion Cell (CutaFlex TM) for Assessing Dermal Exposure to Nanoparticles
Creators: name: Viegas, Vanessa Ann
Publisher: name: University of Hertfordshire
Year: 2014
Subjects: dermal absorption
flexing skin
novel in vitro diffusion cell
nanoparticles

description: Nanoparticles are thought to present a unique hazard to human health. Furthermore, the increasing use of nanomaterials in consumer products has not been accompanied by relevant risk assessments. It is conceivable that skin flexion may assist the translocation of nanoparticles across the stratum corneum. However, current in vitro methodology to study dermal absorption involves the exclusive use of immobile skin within diffusion cells. Therefore, a novel skin-flexing diffusion cell system (“CutaFlex™”) was developed to incorporate reproducible skin flexing (2 flexes min-1; 6 mm maximum amplitude). The initial aims of this Thesis were to characterise the CutaFlex™ system to eliminate the possibility of flexion-induced (experimental) skin damage, demonstrate equivalence with historical permeability data to model compounds and assess the effect of skin flexing on barrier disruption. Subsequent work aimed to investigate the hypothesis that nanoparticles require dermal flexion to penetrate intact skin. In supporting these aims, this Thesis also performed work to assess the correlation between direct measurements of skin barrier function (using tritiated water) and transepidermal water loss (TEWL), the effect of flexing on the performance of topical skin protectants (barrier creams) and to further validate in vitro diffusion cell measurements against in vivo data acquired under identical conditions. The results demonstrated that skin flexing did not alter skin barrier function and that the CutaFlex™ system was in general agreement with historical measurements of skin permeability. Furthermore, controlled chemical or physical damage to the stratum corneum was not exacerbated by skin flexing. Skin flexion did not facilitate the dermal absorption of a range of nanoparticles (quantum dots). However, differences in the partitioning of nanoparticles into the stratum corneum were observed (independent of the degree of flexing), with greater amounts of negatively charged nanoparticles found in the superficial layers of the stratum corneum in comparison with positive or neutral nanoparticles. Flexing had a modest effect on the performance of a skin barrier cream which was limited to low dose applications; an effect tentatively ascribed to flexion-induced movement of cream to previously untreated areas. A poor correlation was found between 3H2O water permeability and TEWL flux. Most importantly, there was excellent agreement between in vitro skin permeability studies and in vivo studies (which used a surrogate measure of skin permeability). To summarise, the data in this Thesis has led to the development and characterisation of a novel diffusion cell (CutaFlex™), capable of simultaneously flexing skin whilst performing dermal absorption measurements comparable with the OECD-compliant models.
Using Multi-Modal Bio-Digital Technologies to Support the Assessment of Cognitive Abilities of Children with Physical and Neurological Impairments
Creators: name: Gan, Hock Chye
Publisher: name: University of Hertfordshire
Year: 2015
Subjects: Human System Interaction (HSI)
non-hand held devices
eye-track
brain-computer interface (BCI)
multi-modal human computer interface
Wisconsin Card Sorting Test (WCST)
Early Concept Development Test (ECDT)
probability streaks
disabled children
Physical and Neurological Impairments (PNI)
cerebral palsy
mental workload in multi-tasking

description: Current studies done using a learning test for children have problems as they only make evaluations of Physically and Neurologically Impaired (PNI) children who can succeed in the test and can be considered as a PASS/FAIL test. This pilot study takes a holistic view of cognitive testing of PNI children using a user-test-device triad model and provides a framework using non-PNI children and adults as controls. Comparisons using adapted off-the-shelf novel interfaces to the computer, in particular, an Electroencephalograph (EEG) head-set, an eye-tracker and a head-tracker and a common mouse were carried out. In addition, two novel multi-modal technologies were developed based on the use of brain-waves and eye-tracking as well as head-tracking technologies to support the study. The devices were used on three tests with increasing cognitive complexity. A self-developed measure based on success streaks (consecutive outcomes) was introduced to improve evaluations of PNI children. A theoretical model regarding a fit of ability to devices was initially setup and finally modified to fit the view of the empirical model that emerged from the outcomes of the study. Results suggest that while multi-modal technologies can address weaknesses of the individual component modes, a compromise is made between the user’s ability for multi-tasking between the modes and the benefits of a multi-modal device but the sample size is very small. Results also show children failing a test with a mouse but passing it subsequently when direct communication is used suggesting that a device can affect a test for children who are of a developing age. This study provides a framework for a more meaningful conversation between educational psychologists as well as other professionals and PNI parents because it provides more discrimination of outcomes in cognitive tests for PNI children. The framework provides a vehicle that addresses scientifically the concerns of parents and schools.
Syntheses of polyalkylated imidazoles
Creators: name: Sigvart Evjen
name: Fiksdahl, Anne
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology
subject: Plant Biology

description: We have developed improved general simple methods for large-scale preparation of polyalkylated imidazoles by improved multicomponent synthesis from commercially available starting materials. A large range of NH- and N-alkyl-polyalkylimidazoles (40 in total, including novel compounds) has been synthesized.
Synthesis, molecular modeling of N-acyl benzoazetinones and their docking simulation on fungal modeled target
Creators: name: Inul Ansary
name: Arijit Das
name: Parth Sarthi Sen Gupta
name: Bandyopadhyay, Amal Kumar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: A series of stable N-acyl benzoazetinones have been synthesized in moderate to good yields (58–85%) from easily available substrates such as 2-(N-acyl) amino benzoic acids through intramolecular amidation under mild conditions. These geometry-optimized benzoazetinones were docked in the model target of P450, class CYP53A15, a benzoate 4-monooxygenase abundantly found in the genome of ascomycetes and Basidiomycetes classes of pathogenic fungi. Low per residue root-mean-square deviation (RMSD) of modeled structure of the enzyme indicated similar topology as template (4D6Z.pdb). Observed score judges site-specific docking, and the interaction of quantum mechanically optimized benzoazetinone derivatives with the target enzyme. These results suggest that 3i is the best antifungal agent. The specific hydrophobic substituent in the benzoazetinones contributed to the stability of ligand–target complex. Overall, the study provided insight into the specificity of the site-specific interactions, thereby, facilitating the possibility of development of broad-spectrum antifungal agents against opportunistic and infectious fungi.
Narratives of Young People Living with a Diagnosis of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)
Creators: name: Solomons, Wendy
Publisher: name: UH Research Archive
Year: 2017
Subjects: chronic fatigue syndrome (CFS)
myalgic encephalomyelitis (ME)
CFS/ME
contested
chronic
medically unexplained symptoms
qualitative
constructionist
narrative
discourse
discursive psychology
children
young people
adolescent

description: CFS/ME (Chronic Fatigue Syndrome/Myalgic Encephalomyelitis) is a distressing and potentially debilitating condition. It can also be understood as a contested condition, surrounded by controversy about its nature, causes and treatment. Previous research indicates that those affected experience this climate of contestation as a troubling and discrediting assault, not only on the nature of their condition, but also on their identities. However, little attention has been paid to the voices of young people living with CFS/ME. This thesis extends a relatively small literature in new directions, focusing a constructionist, discursive narrative lens on the accounts of ten young people (aged 13-18) living with a diagnosis of CFS/ME. Narratives constructed during repeated interviews over a year, and drawing on multimodal materials collected by participants over that period, were analysed for their content, structure and performance, with reference to the local and broader contexts of their production. This analysis demonstrates that teenagers construct rich, multi-layered narratives with the potential to enhance understanding of their situation and broader features of the social world. As they speak of the onset of illness, attempts to live with enduring, unpredictable symptoms and their psychosocial consequences, and (for some) the possibility of “moving on” from the worst of illness, this analysis throws new light on how young people’s narratives can be understood as simultaneously constructing the condition (“M.E.”) and the identities of those involved (“me” and others), in ways that engage with, reflect and resist prevailing discourses. It is argued that the discursive contexts of CFS/ME and adolescence raise particular challenges for young people as they try to construct credible narratives that convey the full extent of their difficulties, while resisting stigmatising identities (eg, as “complaining”, “lazy” or otherwise “not normal”). This analysis highlights implications for them, their families and those who work professionally with them; and for the ongoing social construction of CFS/ME in young people.
Additional file 4: of Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis
Creators: name: Lawlor, Rita
name: Veronese, Nicola
name: Pea, Antonio
name: Nottegar, Alessia
name: Smith, Lee
name: Pilati, Camilla
name: Demurtas, Jacopo
name: Fassan, Matteo
name: Cheng, Liang
name: Luchini, Claudio
Publisher: name: figshare
Year: 2019
Subjects: Space Science
Medicine
Pharmacology
Biotechnology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology
Science Policy

description: Table S3. Methodological quality of cohort studies included in the meta-analysis. This summarizing table shows the method of quality assessment of all the studies included in this systematic review and meta-analysis, using the Newcastle-Ottawa scale. (DOCX 16 kb)
Substratos sociais do sagrado festivo: uma aproximação antropológica
Creators: name: Teixeira, Alfredo
Publisher: name: Comunicação & Cultura
Year: 2010

description: Este ensaio situa-se no quadro de um projecto de pesquisa mais amplo, que tem como objecto as «novas teorias da religião», tomando como ponto de partida a conceptualidade de Wittgenstein, Eliade, Certeau, Bourdieu, Legendre e Girard. Propõe-se uma caracterização antropológica do sagrado festivo a partir de três substratos sociais: a organização da memória social, a regeneração social, a construção simbólica da colectividade.
description: Comunicação & Cultura, n. 10 (2010): A festa
Efficient Synthesis of Substances Related to Cinacalcet Hydrochloride via Heck Coupling
Creators: name: Lei, Fan
name: Qu, Boyi
name: Li, Xiaolong
name: Guo, Li
name: Guan, Mei
name: Hai, Li
name: Jin, Hui
name: Wu, Yong
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Pharmacology
Molecular Biology
Physics
Engineering
Biochemistry
Biophysics

description: Efficient synthetic methods to process substances related to cinacalcet hydrochloride 1, generated during the preparation, were described. The compounds were identified as [1-(7,8-dihydro-naphthalen-1-yl)-ethyl]-[3-(3-trifluoromethyl-phenyl)-propyl]-amine hydrochloride 2,[1-(5,6,7,8-tetrahydro-naphthalen-1-yl)-ethyl]-[3-(3-trifluoromethyl-phenyl)-propyl]-amine hydrochloride 3 and [1-(naphthalen-2-yl)-ethyl]-[3-(3-trifluoromethyl-phenyl)-propyl]-amine hydrochloride 4. All were prepared from commercially available materials in several linear steps and characterized by their respective spectral data.
Há festa na família…: contributos da psicologia para o estudo de rotinas, tradições, celebrações e rituais familiares
Creators: name: Pinto, Helena Rebelo
name: Ribeiro, Maria Teresa
Publisher: name: Comunicação & Cultura
Year: 2010

description: Apresenta-se uma revisão da literatura respeitante ao estudo de rotinas, tradições, celebrações e rituais, tomando a Família como enquadramento sociológico e os modelos de funcionamento familiar como referência conceptual. Nomeadamente, o paradigma do Ciclo de Vida Familiar (Carter & McGoldrick, 2001), através dos seus conceitos fundamentais, proporciona uma fundamentação teórica adequada à análise do tema Festa, às suas tipologias, bem como à sua natureza e significado para a Família. Do percurso conceptual seguido ressalta a importância do grupo familiar como referencial situacional adequado e útil para a compreensão do conceito de Festa, facilitando também a análise das suas múltiplas formas de expressão, culturalmente enraizadas. Por fim, emerge a importância da função desenvolvimental da Festa para a Família e para cada um dos seus membros, constituindo-se, por isso, como um desafio à acção educativa, social e terapêutica.
description: Comunicação & Cultura, n. 10 (2010): A festa