cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Assembly of Trunk and Limb Blood Vessels Involves Extensive Migration and Vasculogenesis of Somite-Derived Angioblasts
Creators: name: Burke, Ann
name: Ambler, Carrie
name: Bautch, Victoria
name: Nowicki, Julie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Vascular development requires the assembly of precursor cells into blood vessels, but how embryonic vessels are assembled is not well understood. To determine how vascular cells migrate and assemble into vessels of the trunk and limb, marked somite-derived angioblasts were followed in developing embryos. Injection of avian somites with the cell-tracker DiI showed that somite-derived angioblasts in unperturbed embryos migrated extensively and contributed to trunk and limb vessels. Mouse-avian chimeras with mouse presomitic mesoderm grafts had graft-derived endothelial cells in blood vessels at significant distances from the graft, indicating that mouse angioblasts migrated extensively in avian hosts. Mouse graft-derived endothelial cells were consistently found in trunk vessels, such as the perineural vascular plexus, the cardinal vein, and presumptive intersomitic vessels, as well as in vessels of the limb and kidney rudiment. This reproducible pattern of graft colonization suggests that avian vascular patterning cues for trunk and limb vessels are recognized by mammalian somitic angioblasts. Mouse-quail chimeras stained with both the quail vascular marker QH1 and the mouse vascular marker PECAM-1 had finely chimeric vessels, with graft-derived mouse cells interdigitated with quail vascular cells in most vascular beds colonized by graft cells. Thus, diverse trunk and limb blood vessels have endothelial cells that developed from migratory somitic angioblasts, and assembly of these vessels is likely to have a large vasculogenic component.
(2528) Marie Henriette Josephine "Jeanne" Aubry
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(2527) Thomas E Woolard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
LEADCOR User's Manual - Leadership Competencies in Correctional Settings - Module I -Stress and Burnout
Creators: name: Pires, Ana
name: Fernandes, ÂNgela
Publisher: name: Zenodo
Year: 2023
Subjects: Leadership
Stress
Burnout

description: Students' LEADCOR User’s Manual - Leadership Competencies in Correctional Settings - Module I -Stress and Burnout
Search for a Lorentz invariant velocity distribution of a relativistic gas
Creators: name: Curado, Evaldo M. F.
name: Germani, Felipe T. L.
name: Soares, Ivano Damiao
Publisher: name: arXiv
Year: 2015
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We examine numerically and analytically the problem of the relativistic velocity distribution in a 1-dim relativistic gas in thermal equilibrium. Our derivation is based on the special theory of relativity, the central limit theorem and the Lobachevsky structure of the velocity space of the theory, where the rapidity variable plays a crucial role. For v^2/c^2 << 1 and 1/β= k_B T/ m_0 c^2 << 1 the distribution tends to the Maxwell-Boltzmann distribution.
description: 15 pages, 4 figures
Using species traits to understand the mechanisms driving pollination and pest control ecosystem services
Creators: name: Greenop, Arran
Publisher: name: Lancaster University
Year: 2020

description: Modern intensive agricultural practices characteristic of Western Europe and North America, such as high usage of agro-chemicals, are cited as key drivers of biodiversity declines. Declines in biodiversity are likely to impact on a number of natural processes termed ‘ecosystem services’, which include pollination and pest control that play an important role in agricultural production. Because of the negative effects of intensive agricultural practices, there has been a search for alternative systems of production. One approach is ecological intensification, where ecosystem services are maximised in agriculture as a way to offset anthropogenic inputs that can damage the wider environment. Key to the success of ecological intensification is gaining a mechanistic understanding of how biodiversity supports the functioning of ecosystem services, so management can be targeted to maximise service delivery. In order to ensure that food production is sustainable in the face of constantly changing environments it is also important to understand how biodiversity responds to stressors, such as insecticide use. This thesis focuses on using invertebrate species morphological and behavioural characteristics—referred to collectively as traits—to gain a mechanistic understanding of how different components of biodiversity support the functioning and resilience of pollination and pest control ecosystem services. Results highlight that trait approaches provide higher accuracy in predicting the functioning and resilience of natural pest control and pollination, than measures such as species richness. I also highlight that common environmental stressors such as insecticides and extreme heat have the potential to limit pest control and pollination ecosystem services, respectively. My results broadly demonstrate that utilising invertebrate species behavioural and morphological traits are beneficial in understanding the mechanisms driving pollination and pest control ecosystem services.
Additional file 1 of Unilateral symptomatic Achilles tendinopathy has limited effects on bilateral lower limb ground reaction force asymmetries and muscular synergy attributes when walking at natural and fast speeds
Creators: name: Lalumiere, Mathieu
name: Bourbonnais, Daniel
name: Goyette, Michel
name: Perrino, Sarah
name: Desmeules, François
name: Gagnon, Dany H.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Additional file 1.
The Mass-Luminosity Relation in the L/T Transition: Individual Dynamical Masses for the New J-Band Flux Reversal Binary SDSSJ105213.51+442255.7AB
Creators: name: Dupuy, Trent J.
name: Liu, Michael C.
name: Leggett, S. K.
name: Ireland, Michael J.
name: Chiu, Kuenley
name: Golimowski, David A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We have discovered that SDSSJ105213.51+442255.7 (T0.5$\pm$1.0) is a binary in Keck laser guide star adaptive optics imaging, displaying a large J-to-K-band flux reversal ($Δ$J = -0.45$\pm$0.09 mag, $Δ$K = 0.52$\pm$0.05 mag). We determine a total dynamical mass from Keck orbital monitoring (88$\pm$5 $M_{\rm Jup}$) and a mass ratio by measuring the photocenter orbit from CFHT/WIRCam absolute astrometry ($M_B/M_A$ = 0.78$\pm$0.07). Combining these provides the first individual dynamical masses for any field L or T dwarfs, 49$\pm$3 $M_{\rm Jup}$ for the L6.5$\pm$1.5 primary and 39$\pm$3 $M_{\rm Jup}$ for the T1.5$\pm$1.0 secondary. Such a low mass ratio for a nearly equal luminosity binary implies a shallow mass$-$luminosity relation over the L/T transition ($Δ$log$L_{\rm bol}$/$Δ$log$M = 0.6^{+0.6}_{-0.8}$). This provides the first observational support that cloud dispersal plays a significant role in the luminosity evolution of substellar objects. Fully cloudy models fail our coevality test for this binary, giving ages for the two components that disagree by 0.2 dex (2.0$σ$). In contrast, our observed masses and luminosities can be reproduced at a single age by "hybrid" evolutionary tracks where a smooth change from a cloudy to cloudless photosphere around 1300 K causes slowing of luminosity evolution. Remarkably, such models also match our observed JHK flux ratios and colors well. Overall, it seems that the distinguishing features SDSSJ1052+4422AB, like a J-band flux reversal and high-amplitude variability, are normal for a field L/T binary caught during the process of cloud dispersal, given that the age (1.11$^{+0.17}_{-0.20}$ Gyr) and surface gravity (log$g$ = 5.0$-$5.2) of SDSSJ1052+4422AB are typical for field ultracool dwarfs.
description: Accepted to ApJ; 33 pages, 8 figures, 5 tables
(2526) Augusta Anne Pierrow Woollard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Cyclin E and Its Associated cdk Activity Do Not Cycle during Early Embryogenesis of the Sea Urchin
Creators: name: Schnackenberg, Bradley
name: Wessel, Gary
name: Nichols, Jason
name: Canman, Julie
name: Moore, Jennifer
name: Sumerel, Jan
name: Marzluff, William
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Female sea urchins store their gametes as haploid eggs. The zygote enters S-phase 1 h after fertilization, initiating a series of cell cycles that lack gap phases. We have cloned cyclin E from the sea urchin Cyclin E is synthesized during oogenesis, is present in the germinal vesicle, and is released into the egg cytoplasm at oocyte maturation. Cyclin E synthesis is activated at fertilization, although there is no increase in cyclin E protein levels due to continuous turnover of the protein. Cyclin E protein levels decline in morula embryos, while cyclin E mRNA levels remain high. After the blastula stage, cyclin E mRNA and protein levels are very low, and cyclin E expression is predominant only in cells that are actively dividing. These include cells in the left coelomic pouch, which forms the adult rudiment in the embryo. The cyclin E present in the egg is complexed with a protein kinase. Activity of the cyclin E/cdk2 changes little during the initial cell cycles. In particular, cyclin E-cdk2 levels remain high during both S-phase and mitosis. Our results suggest that progression through the early embryonic cell cycles in the sea urchin does not require fluctuations in cyclin E kinase activity.
Analysis and synthesis of slow wave structures for millimetre wave TWTs
Creators: name: Waring, Rob
Publisher: name: Lancaster University
Year: 2020

description: Traveling wave tubes (TWTs) and backward wave oscillators (BWOs) are the only solution for high power amplification and RF generation at millimetre waves and THz frequencies. With advances in microfabrication technology, it is now possible to realise these devices with dimensions to support those frequency regimes. Promising applications of millimetre wave TWTs are as high-power amplifiers for wireless communications systems, imaging and satellite communications. BWOs would enable new plasma diagnostic in nuclear fusion capabilities and high-resolution imaging. TWTs are usually constructed using a helical waveguide as slow wave structure (SWS) by which wave energy can propagate. However, fabrication of a helix small enough to support mm-wave is not feasible. Novel SWSs are required suitable to be fabricated with the available processes. The challenge of the simulation of TWTs or BWOs utilising a new SWS is the lack of fast code and the need to rely on powerful, yet slow, 3D electromagnetic software, which are computationally intensive. Both helices and the coupled cavity TWT can be simulated by fast simulation codes using Lagrangian methods. One of the aims of this thesis is to create a fast code for simulating arbitrary three-dimensional SWS, in particular the double corrugated waveguide. The code was validated by comparison with data of a Ka-band TWT available in literature. The second aim is the design of circuits based on double corrugated waveguide SWSs for TWTs and BWO at different frequency to enable different applications. New topologies of couplers were investigated. Extensive 3-dimensional simulations were performed to define dimensions and performance at different frequency bands.
Effects of chiral imbalance and magnetic field on pion superfluidity and color superconductivity
Creators: name: Cao, Gaoqing
name: Zhuang, Pengfei
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The effects of chiral imbalance and external magnetic field on pion superfluidity and color superconductivity are investigated in extended Nambu--Jona-Lasinio models. We take Schwinger approach to treat the interaction between charged pion condensate and magnetic field at finite isospin density and include simultaneously the chiral imbalance and magnetic field at finite baryon density. For the superfluidity, the chiral imbalance and magnetic field lead to catalysis and inverse catalysis effects, respectively. For the superconductivity, the chiral imbalance enhances the critical baryon density, and the magnetic field results in a de Haas--van Alphan oscillation on the phase transition line.
Drosophila Single-minded Represses Gene Transcription by Activating the Expression of Repressive Factors
Creators: name: Mosher, Jack
name: Estes, Patricia
name: Crews, Stephen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: The Drosophila single-minded gene controls CNS midline cell development by both activating midline gene expression and repressing lateral CNS gene expression in the midline cells. The mechanism by which Single-minded represses transcription was examined using the ventral nervous system defective gene as a target gene. Transgenic-lacZ analysis of constructs containing fragments of the ventral nervous system defective regulatory region identified sequences required for lateral CNS transcription and midline repression. Elimination of Single-minded:Tango binding sites within the ventral nervous system defective gene did not affect midline repression. Mutants of Single-minded that removed the DNA binding and transcriptional activation regions abolished ventral nervous system defective repression, as well as transcriptional activation of other genes. The replacement of the Single-minded transcriptional activation region with a heterologous VP16 transcriptional activation region restored the ability of Single-minded to both activate and repress transcription. These results indicate that Single-minded indirectly represses transcription by activating the expression of repressive factors. Single-minded provides a model system for how regulatory proteins that act only as transcriptional activators can control lineage-specific transcription in both positive and negative modes.
Probing lepton non-universality in tau neutrino Scattering
Creators: name: Liu, Hongkai
name: Rashed, Ahmed
name: Datta, Alakabha
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Recently hints of lepton flavor non-universality emerged in the BaBar and LHCb experiments. In this paper we propose tests of lepton universality in $ν_τ$ scattering. To parametrize the new physics we adopt an effective Lagrangian approach and consider the neutrino deep inelastic scattering processes $ν_τ+ N \to τ+ X$ and $ν_μ+ N \to μ+ X$ where we assume the largest new physics effects are in the $τ$ sector. We also consider an explicit leptoquark model in our calculations. In order to make comparison with the standard model and also in order to cancel out the uncertainties of the parton distribution functions, we consider the ratio of total and differential cross sections of tau-neutrino to muon-neutrino scattering. We find new physics effects that can possibly be observed at the proposed Search for Hidden Particles (SHiP) experiment at CERN.
description: 29 pages, 29 figures. Typos corrected
Additional file 1 of Copper and nanostructured anatase rutile and carbon coatings induce adaptive antibiotic resistance
Creators: name: Wasa, Alibe
name: Aitken, Jack
name: Jun, Hyunwoo
name: Bishop, Catherine
name: Krumdieck, Susan
name: Godsoe, William
name: Heinemann, Jack A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1.Response of E. coli to various concentrations of (A) Tetracycline (C)Chloramphenicol (E) Ciprofloxacin after surviving exposure to stainless steeland NsARC in the dark and (B) Tetracycline (D) Chloramphenicol (F)Ciprofloxacin after surviving exposure to stainless steel and NsARC undervisible light. Table S1 Bonferronicontrasts (light) for E.coli survivors challenged with kanamycin. Table S2 Bonferroni contrasts (Dark) for E. coli survivors challenged with kanamycin. Table S3 Bonferroni contrasts for E. coli survivors challenged with tetracycline. Table S4 Bonferroni contrasts for E. coli survivors challenged with chloramphenicol. Table S5 Bonferronicontrasts for E. colisurvivors challenged with ciprofloxacin. Figure. S2 Response of S. aureus tovarious concentrations of (A) kanamycin (C) vancomycin (E) erythromycin (G)oxacillin (I)tetracycline (K) fusidic acid after surviving exposure tostainless steel and NsARC in the dark and (B) kanamycin (D) vancomycin (F)erythromycin (H) oxacillin (J) tetracycline (L) fusidic acid after survivingexposure to stainless steel and NsARC under visible light. TableS6 Bonferroni contrasts (Dark) for S. aureussurvivors challenged with kanamycin. Table S7 Bonferronicontrasts (light) for S. aureussurvivors challenged with kanamycin. Table S8 Bonferronicontrasts for S. aureussurvivors challenged with vancomycin. Table S9 Bonferronicontrasts S. aureussurvivors challenged with erythromycin. TableS10 Bonferroni contrasts for S. aureussurvivors challenged with oxacillin. Table S11 Bonferronicontrasts for S. aureussurvivors challenged with tetracycline. TableS12 Bonferroni contrasts for S. aureussurvivor challenged with fusidic acid. TableS13 Tukey’s contrasts for E. coli expressing PtolC-mScarletunderuv light. Table S14 Tukey’s contrasts for E. coli expressingPtolC-mScarlet Under high intensityvisible light. Table S15 Tukey’s contrasts for E. coli expressing PtolC-mScarletunderAmbient light. Table S16 Tukey’s contrasts for E. coli expressing PtolC-mScarletinthe dark. Table S17 Tukey’s contrasts for E. coli expressing PsoxS-mScarletunderuv light. Table S18 Tukey’s contrasts for E. coli expressing PsoxS-mScarletunderhigh intensity visible light. Table S19 Tukey’s contrasts for E. coli expressingPsoxS-mScarlet under Ambient light. TableS20 Tukey’s contrasts for E. coli expressing PsoxS-mScarletinthe dark. Table S21: The minimumconcentration (MIC) of each antibiotic in µg/ml necessary to reducethe EOP of each test organism by at least 1000-fold. NT=not tested.
(2525) Gertrude Smith
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A study of positive energy condition in Bianchi V spacetimes via Noether symmetries
Creators: name: Ali, Sajid
name: Hussain, Ibrar
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we use Noether symmetries of the geodesic Lagrangian in Bianchi V spacetimes to study various cosmological solutions of Einstein's field equations. Our first result is the identification of the subalgebras of Noether symmetries of the equations of motions in such spacetimes with dimension 4, 5, 6, 7, 9 or 10 of the maximal algebra of Lie point symmetries of dimension 13. Secondly we give physical interpretation of new cosmological solutions which satisfy positive energy condition and yield critical bounds on the expansion coefficient $α$, in which the underlying non-flat spacetimes carry interesting physical properties. Specifically the energy density behaves in one of the following ways. (i) It is positive and constant for all time. (ii) It varies with time and attains a global maximum after some time and then asymptotically converges to zero. (iii) It increases for all time and attains a maximum value at the asymptotic limit $t\rightarrow \infty$. In particular a non-flat spacetime is obtained that mimics the expansion in a flat FRW universe dominated by vacuum energy such that the expansion factor has the same form in both. However, the energy density is dynamical in the former.
description: Some typos are corrected. Some considerations into f(R) gravity is also carried out in the light of obtained results. Accepted for publication in EPJC
On the Sum of the Square of a Prime and a Square-Free Number
Creators: name: Dudek, Adrian
name: Platt, Dave
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We prove that every integer $n \geq 10$ such that $n \not\equiv 1 \text{mod} 4$ can be written as the sum of the square of a prime and a square-free number. This makes explicit a theorem of Erdős that every sufficiently large integer of this type may be written in such a way. Our proof requires us to construct new explicit results for primes in arithmetic progressions. As such, we use the second author's numerical computation regarding GRH to extend the explicit bounds of Ramaré-Rumely.
description: 12 pages
Additional file 1 of Sex-specific patterns and lifetime risk of multimorbidity in the general population: a 23-year prospective cohort study
Creators: name: Velek, Premysl
name: Luik, Annemarie I.
name: Brusselle, Guy G. O.
name: Stricker, Bruno Ch.
name: Bindels, Patrick J. E.
name: Kavousi, Maryam
name: Kieboom, Brenda C. T.
name: Voortman, Trudy
name: Ruiter, Rikje
name: Ikram, M. Arfan
name: Ikram, M. Kamran
name: de Schepper, Evelien I. T.
name: Licher, Silvan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1. Ascertainment of diseases. A summary of methods of ascertainment of the ten diseases selected diseases.
Stabilization in relation to wavenumber in HDG methods
Creators: name: Gopalakrishnan, J.
name: Lanteri, S.
name: Olivares, N.
name: Perrussel, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: Simulation of wave propagation through complex media relies on proper understanding of the properties of numerical methods when the wavenumber is real and complex. Numerical methods of the Hybrid Discontinuous Galerkin (HDG) type are considered for simulating waves that satisfy the Helmholtz and Maxwell equations. It is shown that these methods, when wrongly used, give rise to singular systems for complex wavenumbers. A sufficient condition on the HDG stabilization parameter for guaranteeing unique solvability of the numerical HDG system, both for Helmholtz and Maxwell systems, is obtained for complex wavenumbers. For real wavenumbers, results from a dispersion analysis are presented. An asymptotic expansion of the dispersion relation, as the number of mesh elements per wave increase, reveal that some choices of the stabilization parameter are better than others. To summarize the findings, there are values of the HDG stabilization parameter that will cause the HDG method to fail for complex wavenumbers. However, this failure is remedied if the real part of the stabilization parameter has the opposite sign of the imaginary part of the wavenumber. When the wavenumber is real, values of the stabilization parameter that asymptotically minimize the HDG wavenumber errors are found on the imaginary axis. Finally, a dispersion analysis of the mixed hybrid Raviart-Thomas method showed that its wavenumber errors are an order smaller than those of the HDG method.
(2524) Elizabeth Alexander
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Drosophila APC2 and APC1 Have Overlapping Roles in the Larval Brain Despite Their Distinct Intracellular Localizations
Creators: name: Peifer, Mark
name: McCartney, Brooke
name: Akong, Kathryn
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The tumor suppressor APC and its homologs, first identified for a role in colon cancer, negatively regulate Wnt signaling in both oncogenesis and normal development, and play Wnt-independent roles in cytoskeletal regulation. Both Drosophila and mammals have two APC family members. We further explored the functions of the Drosophila APCs using the larval brain as a model. We found that both proteins are expressed in the brain. APC2 has a highly dynamic, asymmetric localization through the larval neuroblast cell cycle relative to known mediators of embryonic neuroblast asymmetric divisions. Adherens junction proteins also are asymmetrically localized in neuroblasts. In addition they accumulate with APC2 and APC1 in nerves formed by axons of the progeny of each neuroblast-ganglion mother cell cluster. APC2 and APC1 localize to very different places when expressed in the larval brain: APC2 localizes to the cell cortex and APC1 to centrosomes and microtubules. Despite this, they play redundant roles in the brain; while each single mutant is normal, the zygotic double mutant has severely reduced numbers of larval neuroblasts. Our experiments suggest that this does not result from misregulation of Wg signaling, and thus may involve the cytoskeletal or adhesive roles of APC proteins.
(2523) Willie MacGowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The evaluation of non-topological components in Berry phase and momentum relaxation time in a gapped 3D topological insulator
Creators: name: Sengupta, Parijat
name: Klimeck, Gerhard
name: Bellotti, Enrico
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The zero gap surface states of a 3D-topological insulator host Dirac fermions with spin locked to the momentum. The gap-less Dirac fermions exhibit electronic behaviour different from those predicted in conventional materials. While calculations based on a simple linear dispersion can account for observed experimental patterns, a more accurate match is obtained by including higher order $ \overrightarrow{k}$ terms in the Hamiltonian. In this work, in presence of a time reversal symmetry breaking external magnetic field and higher order warping term, alteration to the topologically ordained Berry phase of $ (2n + 1)π$, momentum relaxation time, and the magneto-conductivity tensors is established.
description: 6 pages 4 figures
(2522) Eliza MacGowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Peaks Sets of Classical Coxeter Groups
Creators: name: Diaz-Lopez, Alexander
name: Harris, Pamela E.
name: Insko, Erik
name: Perez-Lavin, Darleen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 05A05, 05A10, 05A15

description: We say a permutation $π=π_1π_2\cdotsπ_n$ in the symmetric group $\mathfrak{S}_n$ has a peak at index $i$ if $π_{i-1}π_{i+1}$ and we let $P(π)=\{i \in \{1, 2, \ldots, n\} \, \vert \, \mbox{$i$ is a peak of $π$}\}$. Given a set $S$ of positive integers, we let $P (S; n)$ denote the subset of $\mathfrak{S}_n$ consisting of all permutations $π$, where $P(π) =S$. In 2013, Billey, Burdzy, and Sagan proved $|P(S;n)| = p(n)2^{n-\lvert S\rvert-1}$, where $p(n)$ is a polynomial of degree $\max(S)- 1$. In 2014, Castro-Velez et al. considered the Coxeter group of type $B_n$ as the group of signed permutations on $n$ letters and showed that $\lvert P_B(S;n)\rvert=p(n)2^{2n-|S|-1}$ where $p(n)$ is the same polynomial of degree $\max(S)-1$. In this paper we partition the sets $P(S;n) \subset \mathfrak{S}_n$ studied by Billey, Burdzy, and Sagan into subsets of $P(S;n)$ of permutations with peak set $S$ that end with an ascent to a fixed integer $k$ or a descent and provide polynomial formulas for the cardinalities of these subsets. After embedding the Coxeter groups of Lie type $C_n$ and $D_n$ into $\mathfrak{S}_{2n}$, we partition these groups into bundles of permutations $π_1π_2 \cdotsπ_n|π_{n+1}\cdots π_{2n}$ such that $π_1π_2\cdots π_n$ has the same relative order as some permutation $σ_1σ_2\cdotsσ_n \in \mathfrak{S}_n$. This allows us to count the number of permutations in types $C_n$ and $D_n$ with a given peak set $S$ by reducing the enumeration to calculations in the symmetric group and sums across the rows of Pascal's triangle.
description: 24 pages
Additional file 2 of Sex-specific patterns and lifetime risk of multimorbidity in the general population: a 23-year prospective cohort study
Creators: name: Velek, Premysl
name: Luik, Annemarie I.
name: Brusselle, Guy G. O.
name: Stricker, Bruno Ch.
name: Bindels, Patrick J. E.
name: Kavousi, Maryam
name: Kieboom, Brenda C. T.
name: Voortman, Trudy
name: Ruiter, Rikje
name: Ikram, M. Arfan
name: Ikram, M. Kamran
name: de Schepper, Evelien I. T.
name: Licher, Silvan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 2. Sensitivity analysis. Results of the five sensitivity analyses presented.
(2521) Charles MacGowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Drosophila APC2 and APC1 Play Overlapping Roles in Wingless Signaling in the Embryo and Imaginal Discs
Creators: name: McCartney, Brooke
name: Peifer, Mark
name: DeNofrio, Jan
name: Hayden, Melissa
name: Akong, Kathryn
name: Price, Meredith
name: Grevengoed, Elizabeth
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The regulation of signal transduction plays a key role in cell fate choices, and its disregulation contributes to oncogenesis. This duality is exemplified by the tumor suppressor APC. Originally identified for its role in colon tumors, APC family members were subsequently shown to negatively regulate Wnt signaling in both development and disease. The analysis of the normal roles of APC proteins is complicated by the presence of two APC family members in flies and mice. Previous work demonstrated that, in some tissues, single mutations in each gene have no effect, raising the question of whether there is functional overlap between the two APCs or whether APC-independent mechanisms of Wnt regulation exist. We addressed this by eliminating the function of both APC genes simultaneously. We find that APC1 and APC2 play overlapping roles in regulating Wingless signaling in the embryonic epidermis and the imaginal discs. Surprisingly, APC1 function in embryos occurs at levels of expression nearly too low to detect. Further, the overlapping functions exist despite striking differences in the intracellular localization of the two APC family members.
Novel Behavioral and Developmental Defects Associated with Drosophila single-minded
Creators: name: Pielage, Jan
name: Steffes, Georg
name: Lau, Dan
name: Parente, Beth
name: Crews, Stephen
name: Klämbt, Christian
name: Strauss, Roland
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: In Drosophila, the development of the midline cells of the embryonic ventral nerve cord depends on the function of the bHLH-PAS transcription factor Single-minded (Sim). The expression domain of sim, however, is also found anterior and posterior to the developing ventral cord throughout the germ band. Indeed, mutations in sim were identified based on their characteristic cuticle phenotype. Eight abdominal segments (A1–A8) can be easily seen in the larval cuticle, while three more can be identified during embryogenesis. Cells located in A8–A10 give rise to the formation of the genital imaginal discs, and a highly modified A11 segment gives rise to the anal pads that flank the anus. sim is expressed in all these segments and is required for the formation of both the anal pads and the genital imaginal discs. A new temperature-sensitive sim allele allowed an assessment of possible postembryonic function(s) of sim. Reduction of sim function below a 50% threshold leads to sterile flies with marked behavioral deficits. Most mutant sim flies were only able to walk in circles. Further analyses indicated that this phenotype is likely due to defects in the brain central complex. This brain region, which has previously been implicated in the control of walking behavior, expresses high levels of nuclear Sim protein in three clusters of neurons in each central brain hemisphere. Additional Sim localization in the medullary and laminar neurons of the optic lobes may correlate with the presence of ectopic axon bundles observed in the optic lobes of sim mutant flies.
Laminar-turbulent patterning in wall-bounded shear flows: a Galerkin model
Creators: name: Seshasayanan, K.
name: Manneville, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: On its way to turbulence, plane Couette flow - the flow between counter-translating parallel plates - displays a puzzling steady oblique laminar-turbulent pattern. We approach this problem via Galerkin modelling of the Navier-Stokes equations. The wall-normal dependence of the hydrodynamic field is treated by means of expansions on functional bases fitting the boundary conditions exactly. This yields a set of partial differential equations for the spatiotemporal dynamics in the plane of the flow. Truncating this set beyond lowest nontrivial order is numerically shown to produce the expected pattern, therefore improving over what was obtained at cruder effective wall-normal resolution. Perspectives opened by the approach are discussed.
description: to appear in Fluid Dynamics Research; 14 pages, 5 figures
LEADCOR User's Manual - Leadership Competencies in Correctional Settings - Module II -Leadership Conceptual Background
Creators: name: Pires, Ana Rita
name: Fernandes, Ângela
Publisher: name: Zenodo
Year: 2023
Subjects: Leadership
Theories
Corrections

description: Students' LEADCOR User’s Manual - Leadership Competencies in Correctional Settings - Module II -Leadership Conceptual Background
Ass. Professor
Creators: name: Kjær, Christina
Publisher: name: Zenodo
Year: 2021
Subjects: ARRAY
Transcriptomics
mesial temporal lobe epilepsy
re-analysis

description: This is re-analysis of data from a study by Venugopal et al. (J Proteomics Bioinform. 2012;5(2)) obtained from the Gene Expression Omnibus (GEO Accession #GSE25453), who identified changes in gene expression profile of treatment-resistant mTLE by whole human genome microarray analysis on hippocampal (spiking seizure zone) and temporal lobe cortex (non-spiking non-seizure zone) brain tissue samples from ten confirmed cases of treatment resistant mTLE. The main tool for analyzing the data is the IPython notebook ‘ArrayExpress - Raw data analysis2.ipynb’ and a list of python dependencies can be found in the 'requirements.txt' file. Data can be downloaded from www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-25453/.
(2520) Ellen MacGowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(2519) Elizabeth MacGowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(2518) Joseph Whitworth MacGowan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Toward a fractal spectrum approach for neutron and gamma pulse shape discrimination
Creators: name: Liu, Mingzhe
name: Liu, Bingqi
name: Zuo, Zhuo
name: Wang, Lei
name: Zan, Guibin
name: Tuo, Xianguo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: There is a key research issue to accurately select out neutron signals and discriminate gamma signals from a mixed radiation field in the neutron detection. This paper proposes a fractal spectrum discrimination approach by means of different spectrum characteristics of neutron and gamma. Figure of merit and average discriminant error ratio are adopted together to evaluate the discriminant effects. Different neutron and gamma signals with various noises and pulse pile-ups are simulated according to real data in the literature. The proposed approach is compared with the digital charge integration and pulse gradient methods. It is found that the fractal approach exhibits the best discriminant performance among three methods. The fractal spectrum approach is not sensitive to the high frequency noises and pulse pile-ups. It means that the proposed approach takes the advantages of anti-noises and high discriminant ability, and can be used to better discriminate neutron and gamma in neutron detection.
description: 10 pages, 8 figures, 6 tables in Chinese Physics C 2016
(2517) Bathsheba Elizabeth Tinker
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Cyclin B synthesis is required for sea urchin oocyte maturation
Creators: name: Wessel, Gary
name: Voronina, Ekaterina
name: Marzluff, William
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Sea urchins are members of a limited group of animals in which meiotic maturation of oocytes is completed prior to fertilization. This is different from oocytes of most animals such as mammals and amphibians in which fertilization reactivates an arrested meiotic cycle. Using a recently developed technique for in vitro maturation of sea urchin oocytes, we analyzed the role of cyclin B, the regulatory component of maturation-promoting factor, in the control of sea urchin oocyte meiotic induction and progression. Oocytes of the sea urchin Lytechinus variegatus accumulate significant amounts of cyclin B mRNA and protein during oogenesis. We analyzed cyclin B synthetic requirements in oocytes and early embryos by inhibiting cyclin B synthesis with DNA and morpholino antisense oligonucleotides. Cyclin B synthesis is not necessary for the entry of G2-arrested oocytes into meiosis; however, it is required for the proper progression through meiotic divisions. Surprisingly, mature sea urchin eggs contain significant cyclin B protein following meiosis that serves as a maternal store for early cleavage divisions. We also find that cyclin A can functionally substitute for cyclin B in early embryos but not in oocytes. These studies provide a foundation for understanding the mechanism of meiotic maturation independent of the zygotic cell cycle.
Additional file 3 of Sex-specific patterns and lifetime risk of multimorbidity in the general population: a 23-year prospective cohort study
Creators: name: Velek, Premysl
name: Luik, Annemarie I.
name: Brusselle, Guy G. O.
name: Stricker, Bruno Ch.
name: Bindels, Patrick J. E.
name: Kavousi, Maryam
name: Kieboom, Brenda C. T.
name: Voortman, Trudy
name: Ruiter, Rikje
name: Ikram, M. Arfan
name: Ikram, M. Kamran
name: de Schepper, Evelien I. T.
name: Licher, Silvan
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 3. Population characteristics of excluded participants.