Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
Creators: name: Waters, Katrina M.
name: Peng, Yao
name: McPhail, Kerry L.
name: Zhang, Lixin
name: Dorrestein, Kathleen
name: Shi, Wenyuan
name: Allard, Pierre-Marie
name: Gerwick, Lena
name: Torres-Mendoza, Daniel
name: Pogliano, Kit
name: Moore, Bradley S.
name: Houson, Hailey
name: Kleigrewe, Karin
name: Kyle, Jennifer E.
name: Hsu, Cheng-Chih
name: Silva, Denise B.
name: Boya, Cristopher A.P.
name: Litaudon, Marc
name: Charusanti, Pep
name: Pace, Laura A.
name: Sedio, Brian E.
name: Shinn, Paul
name: Liu, Xueting
name: Sims, Amy C.
name: Pevzner, Pavel
name: Gurr, Joshua
name: Aigle, Bertrand
name: Pociute, Egle
name: Rodríguez, Andrés M. C.
name: Gavilan, Ronnie G.
name: Metz, Thomas O.
name: Maansson, Maria
name: Quinn, Robert A.
name: Palsson, Bernhard Ø
name: Dai, Jingqui
name: Carlson, Erin E.
name: Crüsemann, Max
name: Ryffel, Florian
name: Vuong, Lisa
name: Nothias, Louis-Felix
name: Linington, Roger G.
name: Alexandrov, Theodore
name: Phelan, Vanessa V.
name: Kharbush, Jenan J.
name: Zhang, Chen
name: Müller, Rolf
name: Lopes, Norberto P.
name: Phapale, Prasad
name: Bouslimani, Amina
name: Dorrestein, Pieter C.
name: Yang, Yu-Liang
name: Engene, Niclas
name: Elfeki, Maryam
name: McLean, Jeffrey
name: Neupane, Ram
name: O'Neill, Ellis C.
name: Murphy, Brian T.
name: Garg, Neha
name: Almaliti, Jehad
name: Helfrich, Eric J. N.
name: Dutton, Rachel J.
name: Wolfender, Jean-Luc
name: Melnik, Alexey V.
name: Marques, Lucas M.
name: Jelsbak, Lars
name: Baric, Ralph
name: Koyama, Nobuhiro
name: Nielsen, Kristian Fog
name: Johnson, Andrew R.
name: Klitgaard, Andreas
name: Esquenazi, Eduardo
name: Duggan, Brendan M.
name: Northen, Trent
name: Wang, Mingxun
name: Boudreau, Paul D.
name: Gutiérrez, Marcelino
name: Williams, Philip G.
name: Edlund, Anna
name: Michelsen, Charlotte F.
name: Demarque, Daniel P.
name: Mascuch, Samantha J.
name: Mohimani, Hosein
name: Lamsa, Anne
name: Tomasi, Sophie
name: Glukhov, Evgenia
name: Larson, Charles B.
name: Macherla, Venkat
name: Sandoval-Calderón, Mario
name: Jensen, Paul R.
name: Gerwick, William H.
name: Nguyen, Dac-Trung
name: Jadhav, Ajit
name: Meehan, Michael J.
name: Porto, Carla
name: Parrot, Delphine
name: Sidebottom, Ashley M.
name: Peryea, Tyler
name: Floros, Dimitrios J.
name: Vining, Oliver B.
name: Hoffman, Thomas
name: Sanchez, Laura M.
name: Gonzalez, David J.
name: VanLeer, Danielle
name: Vorholt, Julia A.
name: Briand, Enora
name: Sohlenkamp, Christian
name: Watrous, Jeramie
name: Kurita, Kenji L.
name: Kersten, Roland D.
name: Knight, Rob
name: Granatosky, Eve A.
name: Luzzatto-Knaan, Tal
name: Keyzers, Robert A.
name: Jenkins, Stefan
name: Liu, Wei-Ting
name: Traxler, Matthew F.
name: Silva, Ricardo R.
name: Piel, Jörn
name: Duncan, Katherine R.
name: Kapono, Clifford A.
name: Humpf, Hans-Ulrich
name: Nguyen, Don Duy
name: Bandeira, Nuno
name: Carver, Jeremy J.
name: Liaw, Chih-Chuang
name: Agarwal, Vinayak
name: Zeng, Yi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community has no way to share data other than in published papers. Although mass spectrometry techniques are well-suited to high-throughput characterization of natural products, there is a pressing need for an infrastructure to enable sharing and curation of data. We present Global Natural Products Social molecular networking (GNPS, http://gnps.ucsd.edu), an open-access knowledge base for community wide organization and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data. In GNPS crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations. Data-driven social-networking should facilitate identification of spectra and foster collaborations. We also introduce the concept of ‘living data’ through continuous reanalysis of deposited data.