cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Combined pharmacological inhibition of cyclophilins, FK506-finding proteins, Hsp90, and Hsp70 protects cells from clostridium botulinum C2 toxin
Creators: name: Ernst, Katharina
name: Kling, Carolin
name: Landenberger, Marc
name: Barth, Holger
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Bacterial protein toxin
subject: PPIases
subject: FK506 binding proteins
subject: Chaperones
subject: Membrane translocation
subject: Protein interaction
subject: Specific pharmacological inhibition
subject: DDC 610 / Medicine & health
subject: Bacterial proteins
subject: Protein-protein interactions
subject: Botulinum toxins
subject: Molecular chaperones
subject: Cyclophilins

description: The Clostridium botulinum C2 toxin is an exotoxin causing severe enterotoxic symptoms. The C2 toxin consists of the binding/translocation component C2II, and the enzymatic active component C2I. After proteolytic activation, C2IIa forms heptamers that bind C2I. The C2IIa/C2I complex is taken up into mammalian target cells via receptor-mediated endocytosis. Acidification of endosomes leads to conformational changes in both components. C2IIa heptamers form a pore into the endosomal membrane, and C2I becomes unfolded and translocates through the narrow C2IIa pores into the cytosol of the cell. Here, C2I covalently transfers an ADP-ribose moiety from its co-substrate NADC onto G-actin, which leads to depolymerization of F-actin resulting in rounding up of adherent cells. Translocation of C2I into the cytosol depends on the activity of the chaperones Hsp90 and Hsp70 and peptidyl-prolyl cis/trans isomerases of the cyclophilin (Cyp) and FK506-binding protein (FKBP) families. Here, we demonstrated that C2I is detected in close proximity with Hsp90, Cyp40, and FKBP51 in cells, indicating their interaction. This interaction was dependent on the concentration of C2 toxin and detected in mammalian Vero and human HeLa cells. Moreover, the present study reveals that combination of radicicol, VER-155008, cyclosporine A, and FK506, which are specific pharmacological inhibitors of Hsp90, Hsp70, Cyps, and FKBPs, respectively, resulted in a stronger inhibition of intoxication of cells with C2 toxin compared to application of the single inhibitors. Thus, the combination of inhibitors showed enhanced protection of cells against the cytotoxic effects of C2 toxin. Cell viability was not significantly impaired by application of the inhibitor combination. Moreover, we confirmed that the combination of radicicol, VER-155008, CsA, and FK506 in particular inhibit the membrane translocation step of C2I into the cytosol whereas receptor binding and enzyme activity of the toxin were not affected. Our findings further characterize the mode of action of Hsp90, Hsp70, Cyps, and FKBPs during membrane translocation of bacterial toxins and furthermore supply starting points for developing of novel therapeutic strategies against diseases caused by bacterial toxins that depend on Hsp90, Hsp70, Cyps, and FKBPs.
Empathy and the space between: investigating the role of digitally enhanced apparel in promoting remote empathetic connection
Creators: name: Heiss, Leah
Publisher: name: RMIT University
Year: 2024

description: This body of work is the culmination of a two year investigation into the role of electronically enhanced apparel and artefacts in providing empathetic linkage between people who do not share physical space. The research draws from the diverse fields of philosophy, communications theory, neuropsychology, presence technologies and technologically advanced textiles, and proposes that a nexus of these disciplines may provide significant opportunities for enhancing the user interactivity of garments and artefacts. Remote emotional connection is investigated through the creation of sensor embedded garments and artefacts that have been developed in collaboration with a fashion designer and an electronics engineer. The prototypes encourage remote empathetic connection through the real-time transference of heartbeat.

The exegesis is structured into five chapters which consider remote presence, flexible consciousness, the architecture of empathy, plasticity in sense perception and the development of prototypes. The project chapter focuses in the development of and testing of a rnage of garments and artefacts thatt conduct presence information between remotely located people. The garments sense, process, transmit and receive the heartbeat signal (ECG). They are enabled with ECG sensors, signal processing equipment, small vibration motors and radio transceivers which allow users to 'feel' the heartbeat of a remote friend/lover/relative as vibration through their garment. The prototypes aim to enrich the remote communications experience through reintroducing an embodied, tactile dimension that is present in face-to-face communication. A range of user testing trials are discussed in the thesis which have been undertaken to assess the impact of the garments at a conscious and a non-conscious level. Conscious experiences were gauged through qualitative testing by way of interviews and unsolicited written reactions. Non-conscious physiological ractions were assessed by recording ECG throughout user-testing periods. This data has been processed by using HRV (heart rate variability) analysis software, running on MatLab.

The development of biosignal sensing garments has raised a range of issues including: innovative potentials for embedded peripheral awareness media; the expansion of the classical body to incorporate remotely sensed information; the issue iof data semantics and the development of intensely personal non-verbal languages; and the issue of corporeal privacy when one's biological information is exposed for potential download. They also bring into question how our bodily experiences might change when we incorporate remote sensory systems.
D3.4 – GNSS customization options
Creators: name: Voskakis, Michael
name: Kaminiaris, Mike
name: Tsiropoulos, Zisis
name: Krukowski, Artur
Publisher: name: Zenodo
Year: 2023

description: As the AgriBIT GNSS sub-systems have already been developed, the current deliverable presents a set of customization options to best fit the needs of diverse type of applications depending on GNSS in modern Agriculture, together with end users. The current work is directly linked with the WP6 and 7 of the project to correspond to the needs of the pilots and market. This also allows the AgriBIT consortium to exploit the applicability of project results to other markets depending on GNSS needs.
sj-docx-2-ine-10.1177_15910199221133167 - Supplemental material for Outcomes of wake-up stroke undergoing mechanical thrombectomy: A systematic review and meta-analysis
Creators: name: Liu, Michael
name: Kobeissi, Hassan
name: Ghozy, Sherief
name: Kallmes, David F
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Neuroscience

description: Supplemental material, sj-docx-2-ine-10.1177_15910199221133167 for Outcomes of wake-up stroke undergoing mechanical thrombectomy: A systematic review and meta-analysis by Michael Liu, Hassan Kobeissi, Sherief Ghozy and David F Kallmes in Interventional Neuroradiology
sj-docx-1-tct-10.1177_15330338221123109 - Supplemental material for Susceptibility of TNFAIP8, TNFAIP8L1, and TNFAIP2 Gene Polymorphisms on Cancer Risk: A Comprehensive Review and Meta-Analysis of Case–Control Studies
Creators: name: Bhowmik, Khokon Kanti
name: Barek, Md Abdul
name: Aziz, Md. Abdul
name: Islam, Mohammad Safiqul
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 110320 Radiology and Organ Imaging
subject: Biochemistry

description: Supplemental material, sj-docx-1-tct-10.1177_15330338221123109 for Susceptibility of TNFAIP8, TNFAIP8L1, and TNFAIP2 Gene Polymorphisms on Cancer Risk: A Comprehensive Review and Meta-Analysis of Case–Control Studies by Khokon Kanti Bhowmik, Md Abdul Barek, Md. Abdul Aziz and Mohammad Safiqul Islam in Technology in Cancer Research & Treatment
High Performance Fractional-N PLL Design and Its Application for 5G New Radio Slides
Creators: Wanghua Wu
Publisher: name: IEEE
Year: 2024

Webinar Slides
Abstract: High performance fractional-N phase-locked loops (PLLs) are essential elements of any
advanced electronic systems. In recent years, both analog and all-digital PLLs employing sampling or sub-sampling phase detector have gained popularity and demonstrated below 100-fs integrated jitter and superior figure-of-merit. This talk focuses on this PLL architecture and elaborates the advanced design techniques to achieve low jitter, low fractional spurs, and low power operation. Both analog circuits design and digital calibration techniques will be presented in detail. In addition, a complete LO chain design example for 5G New Radio will be illustrated in a 28/39 GHz dual-polarized 5G mm-wave cellular chipset, supporting 256-QAM and non-contiguous carrier aggregation.
title: eCHO: Supporting Cancer Patients by recommending Complementary Methods based on Individual Complaints
Creators: name: Hollenbenders, Yasmin
name: Brandl, Lea
name: Kappler, Robin
name: Mezger, Marc
name: Prokosch, Martin
name: Zsebedits, Daniel
name: Zowalla, Richard
name: Hübner, Jutta
name: Wiesner, Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Introduction: Complementary and alternative methods (CAM) are increasingly used by many cancer patients [ref:1]. CAM enable them to actively participate in their healing process. Unfortunately, many patients hesitate to involve their oncologist, yet search CAM on their own [ref:2].[for full text, please go to the a.m. URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Additional file 1 of A non-negative spike-and-slab lasso generalized linear stacking prediction modeling method for high-dimensional omics data
Creators: name: Shen, Junjie
name: Wang, Shuo
name: Dong, Yongfei
name: Sun, Hao
name: Wang, Xichao
name: Tang, Zaixiang
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified

description: Additional file 1. Supplementary figures.
On the largest common subgraph problem
Creators: name: Verbitsky, Oleg
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Largest common subgraph problem
subject: DDC 004 / Data processing & computer science
subject: Graph theory
subject: Teilgraph

description: Given two graphs G 1 = and G 2 = , |V 1I = IV 2| = n, to determine whether they have a size-k common subgraph is one of the earliest examples of an NP-complete problem (by a trivial reduction from the Maximum Clique problem). We show that this problem for equally sized G 1 and G 2, i.e. when IE 1I = IE 2I = m, remains NP-complete.
Origins, procedure and artefact
Creators: name: Shukuroglou, Vicky
Publisher: name: RMIT University
Year: 2024

description: Found and collected natural (organic) and industrial materials are conducive to Vicky Shukuroglou's making of artefacts. They have particular properties of materiality and origin for engagement, interpretation and intervention. Materials are sourced, selected and collected from such diverse environments as urban industries and remote coastal environs. They are chosen for their working properties, personal associations, and qualities such as colour, form, texture, weight, structure and material composition. Her observations of and responses to these diverse environments and their local materials become the influence in the process of making. Objects - such as hair and bone - are investigated and reflected upon as they hold certain qualities that appeal and intrigue, and inspire creative responses. Materials are significantly altered from their original form and utilised for the construction of works, or engaged with as 'objects' for inclusion that remain largely as they were found. They are built onto, extended, reconstructed, enclosed or joined with the constructed elements. Visual energy and ambiguity created from common and opposing qualities is considered and utilised in the interpretation of found forms. In the building of these objects or assemblages, they take on a detailed and intimate identity, whose scale expands beyond the hand held object.

The process and activity of making is a vehicle for further observation and learning, generating an understanding and insight into the relationships of place, structure, form, movement, space, and personal methodologies.
title: Akzeptanz und Nutzungsverhalten von Fitness-Applikationen durch Mitglieder von Fitnessinstitutionen
Creators: name: Nguyen, Thien My
name: Andrzejewski, Dennis
name: Breitschwerdt, Rüdiger
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Einleitung: Mit der Digitalisierung und der Entwicklung von mobilen Endgeräten entsteht ein neuer Markt für das Gesundheitswesen [ref:1]. Die Kombination aus Digitalisierung und steigendem Konsumenten-Interesse für die Gesundheit bietet daher Chancen für die Etablierung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
title: Telemedizinische Beratung – Realisierung des organisatorischen Prozesses und der Videokonferenz
Creators: name: Hadidi, Lars
name: Gödeke, Jan
name: Panholzer, Torsten
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Anforderungen: Die telemedizinische Beratung ist eine aktuelle und innovative Methode zur Erweiterung der medizinischen Versorgung. Damit findet eine deutliche Zeit- und Kostenersparnis für die Teilnehmer in der heutigen, schnelllebigen Zeit statt. Arztkonsultationen sind leichter möglich [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
title: Persistent Identifiers (PID) as means to improve data protection and transparency of clinical trials
Creators: name: Kuchinke, Wolfgang
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Introduction: Persistent identifiers (PID) have grown in importance for data handling to deal with the growing amount and the increased complexity of data in many areas of research and the PID centered data management might be a solution for the automatisation of data flows and enhanced data provenance.[for full text, please go to the a.m. URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Integrierter Service: das Helpdesk des Kommunikations- und Informationszentrums (kiz) der Universität Ulm
Creators: name: Zwiesler, Karin
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Helpdesk
subject: kiz
subject: Ulm / Kommunikations- und Informationszentrum
subject: Reference services: Libraries
subject: Universities; Germany; Ulm
subject: Auskunftsdienst
subject: Bibliographische Auskunft
subject: Hotline
subject: Ulm / Universität

description: Das Kommunikations- und Informationszentrum (kiz) der Universität Ulm ist eine zentrale Betriebseinheit der Universität, die aus den ehemals selbständigen Einrichtungen Universitätsrechenzentrum, Universitätsbibliothek und der Zentrale für Photographie, Grafik und Reproduktion gebildet wurde. Der bereits vor der Integration in der Universitätsbibliothek bestehende Helpdesk sollte auf die Bedürfnisse der neuen Einrichtung angepasst und ausgebaut werden, um einen globalen 1st Level Support für die Nutzer der vom kiz angebotenen Dienste leisten zu können. Damit wurde ein zentraler Anlaufpunkt für Anfragen von Nutzern und Mitarbeitern etabliert. Der Informationsfluss innerhalb des kiz und nach außen sollte dadurch gebündelt werden, um damit vereinfacht und deutlich effizienter gestaltet zu werden. Hier sollen die praktischen Erfahrungen mit der Umsetzung eines konkreten Serviceangebotes in diesem neuen organisatorischen Rahmen dargestellt werden.
title: Eine neue Plattform für skalierbare Analysen und Abfragen onkologischer Daten
Creators: name: Frommolt, Peter
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Bioinformatik
subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Einleitung: Das Next-Generation Sequencing (NGS) hat sich zu einem Standardwerkzeug für Krebsstudien und klinische Forschung weiterentwickelt. Um die mit der Datenverarbeitung verbundenen technischen Herausforderungen bewältigen zu können, besteht ein hoher Bedarf an Systemen für[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
title: Bäuerliche Erbgewohnheiten in Oberösterreich am Beispiel der Bezirksgerichtssprengel Wels und Bad Leonfelden
Creators: name: Mack, Judith Maria
Year: 2009

description: Ziel dieser empirischen Untersuchung ist es, nicht nur die historische, sondern vor allem die aktuelle Praxis der Generationennachfolge in der Landwirtschaft in Oberösterreich näher zu beleuchten. Beide hängen unabdingbar zusammen. Die Untersuchung stützt sich auf die Auswertung sämtlicher Hofübergabeverträge in den Bezirksgerichtssprengeln Wels und Bad Leonfelden im Zeitraum von 1981 bis 2005 sowie auf die Befragung einer Vielzahl fachkundiger Personen im gesamten oberösterreichischen Raum. Überdies liegen dieser Arbeit Untersuchungen der Anerbenrechtsakten des Bezirksgerichtssprengels Wels und Erfahrungsberichte von Landwirten zugrunde. Zusammenfassend kann festgestellt werden, dass das mit Abstand wichtigste und am häufigesten praktizierte Instrument der bäuerlichen Generationennachfolge der Hofübergabevertrag ist, während die Intestaterbfolge sowie andere Übertragungsarten gänzlich in den Hintergrund treten. Als kritikwürdig in diesem Zusammenhang zeigt sich allerdings der Umstand, dass die Hofnachfolge mittels Übergabevertrag oftmals Regelungsgegenstand einer in Traditionalismus, Detailreichtum und Vertragsmustern befangenen Kautelarjurisprudenz ist, folglich den heutigen Ansprüchen nicht immer genügt. Eine Lösungsmöglichkeit für diese Problematik ist keineswegs die gesetzliche Regelung dieses Vertragstypus, vielmehr werden Vertragsverfasser aufgerufen die individuellen Bedürfnisse der Parteien über die Antiquiertheit starrer Vertragsmuster zu stellen. Trotz des starken Überwiegens der vorweggenommenen Erbfolge kann dem Anerbenrecht, als gesetzliche Erbfolge in Bauerngüter, keinesfalls die Nützlichkeit abgesprochen werden. Es ist ein unverzichtbares Instrumentarium, welches trotz eines gewissen Reformbedarfs im „Notfall“ den Weiterbestand eines Hofes zu garantieren vermag.
title: Integrating relational data into clinical information model based data repositories
Creators: name: Tute, Erik
name: Haarbrandt, Birger
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Introduction: A Clinical data warehouse (CDW) is a means for making routine data available for secondary use e.g. for supporting research. A clinical information model (CIM) based CDW has potential merits [ref:1], [ref:2]. Hannover Medical School (MHH) has a CDW based on a relational[for full text, please go to the a.m. URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Ionic liquid electrolytes for safer lithium batteries : I. investigation around optimal formulation
Creators: name: Moreno, M.
name: Simonetti, E.
name: Appetecchi, G. B.
name: Carewska, M.
name: Montanino, M.
name: Kim, G.-T.
name: Loeffler, N.
name: Passerini, S.
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: PYR13FSI
subject: Ionic liquid electrolyte mixtures
subject: PYR13TFSI
subject: DDC 540 / Chemistry & allied sciences
subject: Trapped ions
subject: Grafit

description: In this paper we report on the investigation of ionic liquid-based electrolytes with enhanced characteristics. In particular, we have studied ternary mixtures based on the lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) salt and two ionic liquids sharing the same cation (N-methyl-N-propyl pyrrolidinium, PYR13), but different anions, bis(trifluoromethanesulfonyl)imide (TFSI) and bis(fluorosulfonyl)imide (FSI). The LiTFSI-PYR13TFSI-PYR13FSI mixtures, found to be ionically dissociated, exhibit better ion transport properties (about 10−3 S cm−1 at −20°C) with respect to similar ionic liquid electrolytes till reported in literature. An electrochemical stability window of 5 V is observed in carbon working electrodes. Preliminary battery tests confirm the good performance of these ternary electrolytes with high-voltage NMC cathodes and graphite anodes
title: MAGIC – Ein Grund zum FHIRn? Der Brückenschlag zwischen inhaltlicher Erstellung und digitaler Verarbeitung von modularen Einwilligungen
Creators: name: Bialke, Martin
name: Geidel, Lars
name: Wolff, Robert
name: Lablans, Martin
name: Tremper, Galina
name: Drepper, Johannes
name: Bronsch, Tobias
name: Borg, Andreas
name: Bahls, Thomas
name: Hoffmann, Wolfgang
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Epidemiologie
subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Erhebung personenbezogener Daten erfordert im Regelfall die informierte Einwilligung des Betroffenen, den sogenannten Informed Consent (IC). Der TMF e.V. stellt neben dem generischen Datenschutz-Leitfaden [ref:1] Publikationen und Hilfsmittel zur Erstellung der notwendigen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Animated proportional Venn diagrams: a study into their description, construction and business application
Creators: name: Hingston, Phillip
Publisher: name: RMIT University
Year: 2024

description: Anecdotal observation of the way in which data visualisation techniques are utilised to present relationships in data to audiences informed the author's view that data visualisation had not evolved to utilise the capabilities of ubiquitous business computer equipment. In an information rich but attention poor business environment, a search for a new tool was undertaken to supplement those techniques available to help audiences understand statistical relationships in presentation data.

This search resulted in the development of a practical software tool based on animated Venn diagrams (Dvenn) that attempted to exploit the inherent human ability to perceive quantities visually, a faculty described herein as visual numeracy. The exploitation of this faculty is considered here to be a valuable aid for group understanding of business presentation data. The development of the tool was an essential part of the research that was undertaken and the resulting software forms a significant portion of this practise based research. The aim of the software development was to develop a readily accessible tool that could be utilised in a non-specialist business environment to better facilitate an honest shared meaning of numerical data between a presenter and their audience.

The development of the tool progressed through a number of iterations and the software that accompanies this work is an important component that needs to be viewed in conjunction with the text. The test of the final version was undertaken with undergraduate University students in an attempt to validate the efficacy of the data visualisation technique. The test of the Dvenn software was made against the mature yardstick of scatter-plots. Interestingly, the correlations presented by scatter-plot were not as readily identified as would have been assumed, however, the results for the Dvenn tests were not supportive of the technique for widespread adoption. Nevertheless, further research into the best method of harnessing visual numeracy would seem to be justified.
The politics of empowerment in Australian critical social work
Creators: name: Bay, Uschi
Publisher: name: RMIT University
Year: 2024

description: Critical social workers seek to practice in empowering ways with marginal groups and to transform power relations in organisations and society generally. This thesis explores how Foucault’s theorising has been used by Australian critical social workers to think about power and empowerment practice. However there are many authors who contest that Foucault’s theorising is useful for any kind of liberatory thinking or practice. This makes the use of Foucault’s insights on power to re-formulate empowerment practice contestable.

In this study I aim to draw distinctions between aspects of Foucault’s work that can make a contribution to empowerment practice and those aspects that do not or cannot assist critical social workers to think about empowerment. To draw these theoretical distinctions is particularly timely, as the term “empowerment” itself is used, over-used and misused and appears to have almost contradictory meanings when used by the so-called political left and right.

One of the limitations of Foucault’s insights on power, especially in his early and middle work is the underdeveloped notion of human agency. This short-coming in his theorising led me to draw on the work of a political theorist, Hannah Arendt, who starts with the notion of human agency when theorising power, politics and freedom. Hannah Arendt is a strikingly original and inspirational political thinker. Arendt seeks to reclaim and revalue “the political”. Her understanding of political action is considered novel and I aim to show that it is highly relevant for critical social workers in pursuing empowerment practice. I aim to show that Arendt’s notion of political action adds much to re-thinking critical social work empowerment practice by reflecting on two case studies.

The first case study is focused on empowering the poor in the 1970s Family Centre Project by the Brotherhood of St Laurence. The second case study is about equity practitioners’ work in Victorian Higher Education institutions (1990-1995) aimed at increasing the participation of the disadvantaged in further education. Both case studies aimed to alter and transform power relations and serve as historic specific events for thinking with Arendt and Foucault about power, politics, identity, participation and freedom.
Jahresbericht der Deutschen Gesellschaft für Epidemiologie 2010 – 2011
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2013
Subjects: subject: Jahresbericht DGEpi
subject: DDC 610 / Medicine & health
subject: Epidemiology
subject: Epidemiologie

description: Die „Deutsche Gesellschaft für Epidemiologie (DGEpi) e. V.“ ist eine unabhängige wissenschaftliche Fachgesellschaft, die im Jahr 2005 gegründet wurde und aus der Deutschen Arbeitsgemeinschaft für Epidemiologie (DAE) hervorging. Sie vertritt das Fach Epidemiologie in Forschung und Lehre. Im Zwei-Jahresbericht wird über die Aktivitäten der DGEpi in den Jahren 2010 und 2011 berichtet.
title: Ein Entscheidungsunterstützungssystem für das Informationsmanagement
Creators: name: Kücherer, Christian
name: Jahn, Franziska
name: Höffner, Konrad
name: Schneider, Birgit
name: Paech, Barbara
name: Smers, Stefan
name: Winter, Alfred
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Einleitung: Die Menge an Daten, die bei der Ausführung strategischer, taktischer und operativer Aufgaben im Informationsmanagement im Krankenhaus entstehen, wächst kontinuierlich. Gleichzeitig befinden sich diese Daten in unterschiedlichen Datensenken, Formaten und meist ohne semantische Auszeichnung.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Additional file 1 of Predictive models of recurrent implantation failure in patients receiving ART treatment based on clinical features and routine laboratory data
Creators: name: Fang, Qunying
name: Qiao, Zonghui
name: Luo, Lei
name: Bai, Shun
name: Chen, Min
name: Zhang, Xiangjun
name: Zong, Lu
name: Tong, Xian-hong
name: Wu, Li-min
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy

description: Supplementary Material 1
Longitudinal trajectories of metabolic control from childhood to young adulthood in type 1 diabetes from a large German/Austrian registry: A groupbased modelling approach
Creators: name: Schwandt, Anke
name: Hermann, Julia M.
name: Rosenbauer, Joachim
name: Boettcher, Claudia
name: Dunstheimer, Desiree
name: Grulich-Henn, Jürgen
name: Kuss, Oliver
name: Rami-Merhar, Birgit
name: Vogel, Christian
name: Holl, Reinhard
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: Glycemic control trajectories
subject: Cardiovascular risk-factors
subject: Impact
subject: Complications
subject: DDC 610 / Medicine & health
subject: Adolescent
subject: Child
subject: European Continental Ancestry Group
subject: Prospective Studies
subject: Registries
subject: Young Adult
subject: Risk factors
subject: Blood glucose; Metabolism
subject: Diabetes mellitus, Type 1; Therapy
subject: Body-mass index
subject: Exercise
subject: Multicenter studies
subject: Insulins
subject: Diabetes complications
subject: Glycated hemoglobin A; Metabolism
subject: Glykämischer Index
subject: Risikofaktor
subject: Body-Mass-Index
subject: Körperliche Aktivität
subject: Insulin

description: OBJECTIVE: Worsening of glycemic control in type 1 diabetes during puberty is a common observation. However, HbA1c remains stable or even improves for some youths. The aim is to identify distinct patterns of glycemic control in type 1 diabetes from childhood to young adulthood. RESEARCH DESIGN AND METHODS: A total of 6,433 patients with type 1 diabetes were selected from the prospective, multicenter diabetes patient registry Diabetes-Patienten-Verlaufsdokumentation (DPV) (follow-up from age 8 to 19 years, baseline diabetes duration ≥2 years, HbA1c aggregated per year of life). We used latent class growth modeling as the trajectory approach to determine distinct subgroups following a similar trajectory for HbA1c over time. RESULTS: Five distinct longitudinal trajectories of HbA1c were determined, comprising group 1 = 40%, group 2 = 27%, group 3 = 15%, group 4 = 13%, and group 5 = 5% of patients. Groups 1-3 indicated stable glycemic control at different HbA1c levels. At baseline, similar HbA1c was observed in group 1 and group 4, but HbA1c deteriorated in group 4 from age 8 to 19 years. Similar patterns were present in group 3 and group 5. We observed differences in self-monitoring of blood glucose, insulin therapy, daily insulin dose, physical activity, BMI SD score, body-height SD score, and migration background across all HbA1c trajectories (all P ≤ 0.001). No sex differences were present. Comparing groups with similar initial HbA1c but different patterns, groups with higher HbA1c increase were characterized by lower frequency of self-monitoring of blood glucose and physical activity and reduced height (all P < 0.01). CONCLUSIONS: Using a trajectory approach, we determined five distinct longitudinal patterns of glycemic control from childhood to early adulthood. Diabetes self-care, treatment differences, and demographics were related to different HbA1c courses.
title: Entwicklung eines Tools zum Konvertieren von HL7 FHIR Questionnaires in das MOLGENIS EMX Format
Creators: name: Deppenwiese, Noemi
name: Ulrich, Hannes
name: Wrage, Jan-Hinrich
name: Kock, Ann-Kristin
name: Ingenerf, Josef
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Einleitung: Die Toolbox MOLGENIS [ref:1] ist im Biobanking-Kontext etabliert und verfügt über Module zur Annotierung von Metadaten und dem Matching von Datenelementen. Daten und Metadaten werden in MOLGENIS im entity model extensible (EMX) Tabellenformat gespeichert [ref:2].[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Engaging with modernity: Malay women, non-Western soap opera and watching competencies
Creators: name: Md Syed, Md Azalanshah
Publisher: name: RMIT University
Year: 2024

description: This thesis examines Malay women and their engagement with modernity. One of the most important cultural sites that Malay women can engage in contemporary Malaysia is non-Western soap opera. This television genre has been promoted by the Malaysian authorities as providing appropriate forms of modernity with culturally proximate values for audiences in Malaysia to emulate. The popularity of non-Western soap opera, however, has not been without its critics. Some have argued that non-Western soap operas corrode the standard of Malay womanhood, compromise cultural boundaries and undermine the state’s vision of Malaysian modernity. While this study employs audience ethnography to examine the consumption process of this popular television genre, it argues that Malay women are by no means naïve and unthinking viewers who passively consume non-Western soap opera. Rather they are more rightly seen as fluid consumers who engage with the consumption process as discerning viewers with sophisticated ‘watching competencies’ to deal with the content of these soap operas in a very subtle and complex ways. The field of non-Western soap opera consumption, defined by Malay women’s fluid engagement with global cultural influences on one hand, and the Malaysian state’s prescription of behaviour for its vision of a modern nation on the other, reveals something crucial about the continually renegotiated nature of the Malaysian modernity.
Associations of human milk oligosaccharides with otitis media and lower and upper respiratory tract infections up to 2 years : the Ulm SPATZ Health Study
Creators: name: Siziba, Linda P.
name: Mank, Marko
name: Stahl, Bernd
name: Kurz, Deborah
name: Gonsalves, John
name: Blijenberg, Bernadet
name: Rothenbacher, Dietrich
name: Genuneit, Jon
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: human milk oligosaccharides (HMOs)
subject: otitis media (OM)
subject: lower respiratory tract infections (LRTI)
subject: upper respiratory tract infections (URTI)
subject: human milk groups
subject: targeted LC-MS/MS2
subject: DDC 610 / Medicine & health
subject: Milk, Human; Immunology
subject: Respiratory tract infections
subject: Otitis media
subject: Oligosaccharides
subject: Muttermilch
subject: Immunität
subject: Mittelohrentzündung
subject: Atemwegsinfektion
subject: Oligosaccharide

description: Background: Human milk oligosaccharides (HMOs) support and concurrently shape the neonatal immune system through various mechanisms. Thereby, they may contribute to lower incidence of infections in infants. However, there is limited evidence on the role of individual HMOs in the risk of otitis media (OM), as well as lower and upper respiratory tract infections (LRTI and URTI, respectively) in children up to 2 years. Objective: To investigate whether individual HMO concentrations measured at 6 weeks of lactation were associated with risk of OM, LRTI or URTI up to 2 years in breastfed infants. Associations with OM, LRTI and URTI were determined for the most prominent human milk oligosaccharides including 13 neutral, partly isomeric structures (trioses up to hexaoses), two acidic trioses, and lactose. Design: HMO measurements and physician reported data on infections were available from human milk samples collected at 6 weeks postpartum (n = 667). Associations of HMOs with infections were assessed in crude and adjusted models using modified Poisson regression. Results: Absolute concentrations (median [min, max], in g/L) of 2′-fucosyllactose (2′-FL) tended (p = 0.04) to be lower, while lacto-N-tetraose (LNT) was higher in the milk for infants with OM in the 1st year of life (p = 0.0046). In the milk of secretor mothers, LNT was significantly higher in the milk for infants with OM (RR [95% CI]: 0.98 [0.15, 2.60]) compared to infants without OM (RR [95% CI]: 0.76 [0.14, 2.90]) at 1 year (p = 0.0019). No statistically significant milk group differences and associations were observed for OM, LRTI, and URTI (p > 0.0031). Conclusion: Our findings suggest that neither prominent neutral individual HMOs (ranging from 2′-FL to LNDFHs) nor acidic human milk sialyllactoses or lactose are significantly associated with a reduced or increased risk of infections in infants up to 2 years of age. Further research is needed to determine whether specific HMOs could potentially reduce the incidence or alleviate the course of distinct infections in early life.
SSIEM presentation: Fragment screening for drug discovery in primary hyperoxaluria type 1
Creators: name: Mackinnon, Sabrina
name: Yue, Wyatt
Publisher: name: Zenodo
Year: 2018
Subjects: SSIEM
Hyperoxaluria
HAO1
Fragment screening

description: PowerPoint slides for oral presentation at the SSIEM Annual conference in Athens, September 2018. Talk title was 'Fragment screening for drug discovery in inborn errors of metabolism: Primary hyperoxaluria type 1 as an exemplar target'.
Additional file 2 of Predictive models of recurrent implantation failure in patients receiving ART treatment based on clinical features and routine laboratory data
Creators: name: Fang, Qunying
name: Qiao, Zonghui
name: Luo, Lei
name: Bai, Shun
name: Chen, Min
name: Zhang, Xiangjun
name: Zong, Lu
name: Tong, Xian-hong
name: Wu, Li-min
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy

description: Supplementary Material 2. Figure S1. Prediction model of subsequent first ET cycles in RIF patients The area under the ROC curve (AUC) of the training set was 0.673 (95% CI: 0.597?0.748).
Geological evolution of the Scaliger Crater Region on the Moon: Implications for the boundary of the Australe North Basin and magmatism in the region
Creators: name: Panwar, Neha
name: Srivastava, Neeraj
Publisher: name: figshare
Year: 2022
Subjects: Planetary Geology

description: The M3 mosaic of the study area for: Geological evolution of the Scaliger Crater Region on the Moon: Implications for the boundary of the Australe North Basin and magmatism in the region The crater count files for: Lacus Solitudinis Basalts Bowditch Crater Scaliger Crater
Frontotemporal lobar degeneration case with an N-terminal TUBA4A mutation exhibits reduced TUBA4A levels in the brain and TDP-43 pathology
Creators: name: Van Schoor, Evelien
name: Vandenbulcke, Mathieu
name: Bercier, Valérie
name: Vandenberghe, Rik
name: Van Der Zee, Julie
name: Van Broeckhoven, Christine
name: Otto, Markus
name: Hanseeuw, Bernard
name: Van Damme, Philip
name: Van Den Bosch, Ludo
name: Thal, Dietmar Rudolf
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: TUBA4A
subject: transactive response DNA-binding protein 43 kD
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Frontotemporal dementia
subject: DNA-binding proteins
subject: Frontotemporale Demenz
subject: DNS-Bindungsproteine

description: Recently, disease-associated variants of the TUBA4A gene were identified in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Here, we present the neuropathological report of a patient with the semantic variant of primary progressive aphasia with a family history of Parkinsonism, harboring a novel frameshift mutation c.187del (p.Arg64Glyfs*90) in TUBA4A. Immunohistochemistry showed abundant TAR DNA-binding protein 43 kDa (TDP-43) dystrophic neurite pathology in the frontal and temporal cortex and the dentate gyrus of the hippocampus, consistent with frontotemporal lobar degeneration (FTLD). The observed pathology pattern fitted best with that of FTLD-TDP Type C. qPCR showed the presence of mutant TUBA4A mRNA. However, no truncated TUBA4A was detected at the protein level. A decrease in total TUBA4A mRNA and protein levels suggests loss-of-function as a potential pathogenic mechanism. This report strengthens the idea that N-terminal TUBA4A mutations are associated with FTLD-TDP. These N-terminal mutations possibly exert their pathogenic effects through haploinsufficiency, contrary to C-terminal TUBA4A mutations which are thought to disturb the microtubule network via a dominant-negative mechanism.
sj-pdf-1-jcb-10.1177_0271678X221126280 - Supplemental material for Phenotypic variability in 446 CADASIL patients: Impact of NOTCH3 gene mutation location in addition to the effects of age, sex and vascular risk factors
Creators: name: Dupé, Charlotte
name: Guey, Stéphanie
name: Biard, Lucie
name: Dieng, Sokhna
name: Lebenberg, Jessica
name: Grosset, Lina
name: Alili, Nassira
name: Hervé, Dominique
name: Tournier-Lasserve, Elisabeth
name: Jouvent, Eric
name: Chevret, Sylvie
name: Chabriat, Hugues
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 110306 Endocrinology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 110320 Radiology and Organ Imaging
subject: Cell Biology
subject: Biochemistry
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jcb-10.1177_0271678X221126280 for Phenotypic variability in 446 CADASIL patients: Impact of NOTCH3 gene mutation location in addition to the effects of age, sex and vascular risk factors by Charlotte Dupé, Stéphanie Guey, Lucie Biard, Sokhna Dieng, Jessica Lebenberg, Lina Grosset, Nassira Alili, Dominique Hervé, Elisabeth Tournier-Lasserve, Eric Jouvent, Sylvie Chevret, Hugues Chabriat in Journal of Cerebral Blood Flow & Metabolism
Isotopically varying spectral features of silicon-vacancy in diamond
Creators: name: Dietrich, Andreas
name: Jahnke, Kay D.
name: Binder, Jan M.
name: Teraji, Tokuyuki
name: Isoya, Junichi
name: Rogers, Lachlan J.
name: Jelezko, Fedor
Publisher: name: Universität Ulm
Year: 2014
Subjects: subject: silicon vacancy center
subject: local vibrational mode
subject: phonon sideband
subject: ZPL
subject: DDC 530 / Physics
subject: Diamonds
subject: Isotopes
subject: Phonons
subject: Silicon
subject: Diamant
subject: Isotop
subject: Silicium

description: Abstract The silicon-vacancy centre ( ) in diamond has exceptional spectral properties for single-emitter quantum information applications. Most of the fluorescence is concentrated in a strong zero phonon line (ZPL), with a weak phonon sideband extending for 100 nm that contains several clear features. We demonstrate that the ZPL position can be used to reliably identify the silicon isotope present in a single centre. This is of interest for quantum information applications since only the 29Si isotope has nuclear spin. In addition, we show that the sharp 64 meV phonon peak is due to a local vibrational mode of the silicon atom. The presence of a local mode suggests a plausible origin of the measured isotopic shift of the ZPL.
description: Video Abstract
title: Bacterial ghosts presenting fertility proteins for induction of immunocontraception in possum
Creators: name: Schlacher, Simone
Year: 2009

description: Ziel dieser vorliegenden Arbeit war die Produktion eines immunocontrazeptiven Impfstoffes auf Basis des Bacterial Ghost Systems, um die Opossum (Trichosurus vulpecula) Wildpopulation Neuseelands einzudämmen. Für die Herstellung eines fertilitätskontrollierenden Impfstoffes wurden zunächst vier unterschiedliche Ziel-Sequenzen ausgewählt: ZP2C, Zona Pellucida Protein 2, C-terminale Sequenz ZP2Copt, Zona Pellucida Protein, mit optimiertem Codon für E. coli Expression Cp4, Coat Protein 4 des Conceptus Vap1, Vesicle Associated Protein 1 der frühen Oogenese Die vier oben genannten immunologischen Sequenzen wurden in E. coli produziert, wobei die jeweilige Ziel-Sequenz in den periplasmatischen Raum transportiert wurde. Anschließend wurden die Bakterien durch E-gesteuerte Lyse in Bacterial Ghosts überführt. BG-Impfstoffe, stimulieren auf natürliche Weise das Immunsystem, ohne dass weitere Adjuvanten benötigt werden. Durch die Anwendung der sogenannten Impfstoffe in Opossums soll das Immunsystem der Tiere angeregt werden um eine humorale sowie zelluläre Immunantwort gegen die verwendeten Ziel-Proteine zu induzieren.
title: Recursive Expansive Dynamics
title: Hypatian Math
titleType: AlternativeTitle
title: Formal Proof of Recursive Topological Vertex, Recursive Mirror Symmetry, and Recursive Renormalization Group Flow
titleType: AlternativeTitle
title: Recursive Fractalization in Nonlinear Dynamics and Holographic Systems
titleType: AlternativeTitle
Creators: name: Del Bel, Julian
Publisher: name: Zenodo
Year: 2025

description: This framework scaffolds spectral geometry, operator theory, higher-dimensional and fractal spacetime structures, recursive algebra, and topological invariants—all aiming to capture a deeply recursive and self-modulating cosmos. In many areas of mathematics and physics, the concept of an annihilator—commonly used in affine subspace or dual spaces—captures the idea of “zeroing out” a structure. In our work, we propose an extension of this idea via the Inverse Zero Operator (IZO), a projection operating kernel that recursively extracts the stable, invariant core (the fixed-point) from a given operator sequence. Rather than simply annihilating a structure, the IZO acts as a memory-extracting mechanism, preserving the recursive influence inherent in the system. This paper introduces the IZO, formalizes its properties, and demonstrates its utility through several examples. Our goal is to provide both a rigorous mathematical foundation and an accessible exposition for further exploration in mathematical physics.
description: Running Adelic Integration...

Running Lie Algebra Analysis...
Standard deformation computed successfully.

Performing Cross-Validation...

==================================================
INTEGRATED ANALYSIS RESULTS
==================================================

Quantum-Consistent Adelic Integration Report
============================================
Computed Λ: 1.0
Balancing dx: 161609838460844346271680203925.5221527559065008578318525040070179605415904948086433123860082579364859

Component Structure:
Real Continuum: 6.975357535853769564018389183934484833544679824821000822079731605785973739106144495802573231793827148e+117
p-adic Spectrum: 1.433618269543802008859004043861336657399073684134227538127346850246125858773248934731423341494032307e-118
Prime 2 Contribution: 0.5
Prime 3 Contribution: 0.3333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333
Prime 5 Contribution: 0.2
Prime 7 Contribution: 0.1428571428571428571428571428571428571428571428571428571428571428571428571428571428571428571428571429
Prime 11 Contribution: 0.09090909090909090909090909090909090909090909090909090909090909090909090909090909090909090909090909091
... (and more primes)

Quantum Report:
• Product Deviation: 2.86e-101
• Log Spectral Std Dev: 1.17
• Expected Std Dev: 4.60
• Anomaly Detected: False

Exceptional Lie Algebra Analysis
================================
• Standard Deformation Norm: inf
• Safe Deformation Norm: nan

Cross-Validation Results
=======================
• Deformation Consistency: False
• Metrics Correlation: 0.0000
• System Consistency: False
• Consistency Score: 0.0000