cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: The Limes in the province of Pannonia inferior (AD 106-294)
Creators: name: Gudea, Nicolae
Publisher: name: University Library Heidelberg
Year: 2015

description: Die Arbeit stellt den Abschluss der Untersuchungen des Autors zum Limes in Dakien und seinen Nachbarprovinzen dar. Daher beschränkt sie sich in ihrer historischen Auswertung nicht allein auf eine Darstellung der Entwicklung des Limes in Pannonia inferior und der stationierten Truppen vom 1.-4. Jahrhundert, sondern berücksichtigt in besonderem Maße die enge militärische Verbindung zwischen Pannonia inferior, Dacia superior, Dacia Porolissensis und Moesia superior während der kriegerischen Auseinandersetzungen der Römer mit den Dakern und Sarmaten. Wie schon in den Studien zuvor enthält der Aufsatz einen umfangreichen, reich bebilderten Katalogteil, in dem alle niederpannonischen Kastelle mit ihrer Lage im Gelände, ihren Bauphasen und Hinweisen auf dort nachgewiesene Militäreinheiten beschrieben sind.
description: The article represents the conclusion of the author‘s investigations into the Limes in Dacia and its neighbouring provinces. In its historical evaluation, therefore, it is not only restricted to a representation of the development of the Limes in Pannonia inferior and the troops stationed from the 1st to 4th century, but considers in particular the close military connection between Pannonia inferior, Dacia superior, Dacia Porolissensis and Moesia superior during the warring struggles of the Romans with the Dacians and Sarmatians. As in previous studies the paper contains an extensive, richly illustrated catalogue, in which all Lower Pannonian forts are described together with their topographical situations, construction periods and evidence of military units serving there.
title: AutorInnen dieses Heftes
Creators: name: Redaktion, Die
Publisher: name: University Library Heidelberg
Year: 2015

description: kritische berichte - Zeitschrift für Kunst- und Kulturwissenschaften, Bd. 37, Nr. 1 (2009): kritische berichte, Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
title: G. Ulrich Großmann: Die Welt der Burgen. Geschichte, Architektur, Kultur
Creators: name: Schneider, Alois
Publisher: name: University Library Heidelberg
Year: 2015

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 44, Nr. 2 (2015), Beginn und Erscheinungsfrequenz: Ausgaben pro Band: 4
title: Rasmussen's encephalitis
Creators: name: Shaj, Aswathy
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Neuroradiology
subject: Neuroradiology brain
subject: Paediatric
subject: MR
subject: Clinical Cases

description: Clinical History: An eight-year-old boy presented with recurrent focal tonic-clonic seizures for the past one year. Video EEG showed focal epilepsy of the posterior head region origin. Despite being on anti-epileptic medications he now presented with recurrent focal seizures with weakness of the right upper and lower limbs.

description: 8 years, male
Fast Magnetosonic Waves Observed by Van Allen Probes: Testing Local Wave Excitation Mechanism
Creators: name: Min, Kyungguk
name: Liu, Kaijun
name: Wang, Xueyi
name: Chen, Lunjin
name: Denton, Richard
Publisher: name: American Geophysical Union
Year: 2018

description: Linear Vlasov theory and particle-in-cell (PIC) simulations for electromagnetic fluctuations in a homogeneous, magnetized, and collisionless plasma are used to investigate a fast magnetosonic wave event observed by the Van Allen Probes. The fluctuating magnetic field observed exhibits a series of spectral peaks at harmonics of the proton cyclotron frequency Omega p and has a dominant compressional component, which can be classified as fast magnetosonic waves. Furthermore, the simultaneously observed proton phase space density exhibits positive slopes in the perpendicular velocity space, partial derivative f(p)/partial derivative v(perpendicular to) > 0, which can be a source for these waves. Linear theory analyses and PIC simulations use plasma and field parameters measured in situ except that the modeled proton distribution is modified to have larger partial derivative f(p)/partial derivative v(perpendicular to) under the assumption that the observed distribution corresponds to a marginally stable state when the distribution has already been scattered by the excited waves. The results show that the positive slope is the source of the proton cyclotron harmonic waves at propagation quasi-perpendicular to the background magnetic field, and as a result of interactions with the excited waves the evolving proton distribution progresses approximately toward the observed distribution.
title: ВЛАГООБЕСПЕЧЕННОСТЬ И УРОЖАЙНОСТЬ ОЗИМОЙ ПШЕНИЦЫ ПО ПОЛУПАРУ В ЗЕРНОВЫХ СЕВООБОРОТАХ С ЧИСТЫМ И ЗАНЯТЫМ ПАРОМ В ЗАСУШЛИВОЙ ЗОНЕ СТАВРОПОЛЬСКОГО КРАЯ
Creators: name: МОРОЗОВ , Николай Александрович
Publisher: name: ИЗВЕСТИЯ ГОРСКОГО ГОСУДАРСТВЕННОГО АГРАРНОГО УНИВЕРСИТЕТА
Year: 2019

description: Определение запасов продуктивной влаги в различные периоды роста и развития растений, а также изучение влияния различных звеньев севооборота на урожайность повторной озимой пшеницы является актуальным. Исследования проводили в 2012-2017 гг. в засушливой зоне Ставрополья, в отделе земледелия Прикумской опытно-селекционной станции в двух 6-польных зерновых севооборотах, различающихся чистым и занятым паром. Цель исследований - изучение влияния различных звеньев севооборота на урожайность второй озимой пшеницы. Посев проводили в оптимальные сроки с 1 по 10 октября. Продолжительность появления всходов по годам значительно различалась (10-38 дней). Запасы влаги в пахотном слое почвы перед посевом озимой пшеницы составляли в среднем 16,2 мм, в метровом - 49,9 мм, к началу весенней вегетации - 117,3 мм, а к уборке - 45,8 мм. Эффективность использования влаги из почвы составила в среднем 33%, а весенне-летних осадков - 67%. Однако, в одни годы (2014 г.) влаги больше (53,2%) потреблялось из почвы, а в другие годы (2017 г.) - из осадков (100%). Самое продуктивное использование влаги наблюдали в 2016 и 2017 гг. (74-75 мм/т), а наименее продуктивное (171 мм/т) в засушливом 2012 г. Максимальная урожайность второй озимой пшеницы в двух севооборотах получена в 2014 и 2017 гг., а минимальная - в 2013 и 2012 гг. По урожайности лидировал севооборот с занятым паром. Прибавка в урожае на контроле составила 0,93 т/га или 89,4%, а на удобренном фоне - 0,78 т/га или 42,6% в сравнении с севооборотом с чистым паром. За ротацию урожайность в севообороте с занятым паром на контроле на 0,14 т/га выше, чем на удобренном фоне в севообороте с чистым паром. Эффективность использования минеральных удобрений была примерно одинаковой. Возделывание в севообороте бобовой культуры позволяет дополнительно получить продукцию, обогатить почву азотом и значительно снизить применение минеральных удобрений в зерновых севооборотах.
title: УРОЖАЙНОСТЬ ОЗИМОЙ ПШЕНИЦЫ ПОСЛЕ КУКУРУЗЫ НА ЗЕЛЁНЫЙ КОРМ В ЗЕРНОВЫХ СЕВООБОРОТАХ С ЧИСТЫМ И ЗАНЯТЫМ ПАРОМ
Creators: name: НИКОЛАЙ АЛЕКСАНДРОВИЧ, АЛЕКСАНДР ИВАНОВИЧ, ЕЛЕНА НИКОЛАЕВНА, МОРОЗОВ, ХРИПУНОВ , ОБЩИЯ
Publisher: name: Оренбургский государственный аграрный университет
Year: 2019

description: Цель исследования - изучение влияния различных звеньев севооборота на урожайность озимой пшеницы по предшественнику кукуруза на зелёный корм. Исследование проведено в засушливой зоне Ставропольского края в двух шестипольных зерновых севооборотах, различающихся чистым и занятым паром, в 2012-2017 гг. Озимая пшеница высевалась в оптимальные сроки с 1 по 10 октября. Результаты исследования показали, что два севооборота, различающиеся только наличием чистого и занятого пара, по-разному влияют на урожайность озимой пшеницы и эффективность использования минеральных удобрений по предшественнику кукуруза на зелёный корм. Максимальная урожайность озимой пшеницы в севооборотах как с чистым, так и с занятым паром получена в 2015 г., а минимальная - в 2013 г. В среднем за 6 лет исследования, или полную ротацию севооборотов, урожайность озимой пшеницы в севообороте с занятым паром была почти такая же, как в севообороте с чистым паром на удобренном фоне. Т.е. возделывание занятого пара (эспарцета на зелёный корм) позволяет не только дополнительно получить продукцию, обогащая почву корневыми остатками, но и значительно снизить применение минеральных удобрений в зерновых севооборотах засушливой зоны.
title: The origin of orbitotemporal diversity in lepidosaurs: insights from tuatara chondrocranial anatomy
Creators: name: Yaryhin, Oleksandr
name: Werneburg, Ingmar
Publisher: name: Senckenberg Gesellschaft für Naturforschung
Year: 2019

description: Sphenodon punctatus, the tuatara, is the last survivor of the formerly widely distributed group of Rhynchocephalia, which is the sister group of Squamata. The skull anatomy of S. punctatus and its fossil relatives is comparably well known; however, embryological data of skull development are rare, incomplete, and mostly represented by dated works. Knowing the anatomy of the chondrocranium of S. punctatus is crucial to an understanding of chondrocranial evolution in reptiles and particularly in lepidosaurs. Here, based on the historical histological collection of Hugo Schauinsland, we reexamined the anatomy of the fully formed chondrocranium in S. punctatus and describe a very early stage of its chondrocranium formation, which was not considered in any previous study. The architecture of the fully formed chondrocranium of S. punctatus represents one of the most complex ones among sauropsids. We observed a number of characters, that are absent in other reptiles and were never previously described in S. punctatus. We consider the robust lateral braincase wall in S. punctatus to represent an ancestral condition. In the lepidosaurian ancestor it likely had the potential for further diversification of the orbitotemporal region in squamates. Certainly, it provided extra mechanical strength to the chondrocranium as a whole. At the same time, the strong cartilaginous lateral wall of the chondrocranium in S. punctatus could also be a rudimentary form of the more distant ancestor of lepidosaurs, in which the chondrocranium played a more functional role.
A growing importance of large fires in conterminous United States during 1984-2012
Creators: name: Yang, Jia
name: Tian, Hanqin
name: Tao, Bo
name: Ren, Wei
name: Pan, Shufen
name: Liu, Yongqiang
name: Wang, Yuhang
Publisher: name: American Geophysical Union
Year: 2015

description: Fire frequency, extent, and size exhibit a strong linkage with climate conditions and play a vital role in the climate system. Previous studies have shown that the frequency of large fires in the western United States increased significantly since the mid-1980s due to climate warming and frequent droughts. However, less work has been conducted to examine burned area and fire emissions of large fires at a national scale, and the underlying mechanisms accounting for the increases in the frequency of large fires are far from clear. In this study, we integrated remote-sensed fire perimeter and burn severity data sets into the Dynamic Land Ecosystem Model to estimate carbon emissions from large fires (i.e., fires with size larger than 1000acres or 4.05km(2)) in conterminous United States from 1984 to 2012. The results show that average area burned by large fires was 1.44x10(4)km(2)yr(-1) and carbon emissions from large fires were 17.65TgCyr(-1) during the study period. According to the Mann-Kendall trend test, annual burned area and pyrogenic carbon emissions presented significant upward trends at the rates of 810km(2)yr(-1) and 0.87TgCyr(-1), respectively. Characteristic fire size (fire size with the largest contribution to the total burned area) in the period of 2004-2012 increased by 176.1% compared to the period of 1984-1993. We further found that the larger fires were associated with higher burn severity and occurred more frequently in the warmer and drier conditions. This finding implies that the continued warming and drying trends in the 21st century would enhance the total burned area and fire emissions due to the contributions of larger and more severe wildfires.
Spectral properties and associated plasma energization by magnetosonic waves in the Earth's magnetosphere: Particle-in-cell simulations
Creators: name: Sun, Jicheng
name: Gao, Xinliang
name: Lu, Quanming
name: Chen, Lunjin
name: Liu, Xu
name: Wang, Xueyi
name: Tao, Xin
name: Wang, Shui
Publisher: name: American Geophysical Union
Year: 2017

description: In this paper, we perform a 1-D particle-in-cell (PIC) simulation model consisting of three species, cold electrons, cold ions, and energetic ion ring, to investigate spectral structures of magnetosonic waves excited by ring distribution protons in the Earth's magnetosphere, and dynamics of charged particles during the excitation of magnetosonic waves. As the wave normal angle decreases, the spectral range of excited magnetosonic waves becomes broader with upper frequency limit extending beyond the lower hybrid resonant frequency, and the discrete spectra tends to merge into a continuous one. This dependence on wave normal angle is consistent with the linear theory. The effects of magnetosonic waves on the background cold plasma populations also vary with wave normal angle. For exactly perpendicular magnetosonic waves (parallel wave number k(parallel to) = 0), there is no energization in the parallel direction for both background cold protons and electrons due to the negligible fluctuating electric field component in the parallel direction. In contrast, the perpendicular energization of background plasmas is rather significant, where cold protons follow unmagnetized motion while cold electrons follow drift motion due to wave electric fields. For magnetosonic waves with a finite k(parallel to), there exists a nonnegligible parallel fluctuating electric field, leading to a significant and rapid energization in the parallel direction for cold electrons. These cold electrons can also be efficiently energized in the perpendicular direction due to the interaction with the magnetosonic wave fields in the perpendicular direction. However, cold protons can be only heated in the perpendicular direction, which is likely caused by the higher-order resonances with magnetosonic waves. The potential impacts of magnetosonic waves on the energization of the background cold plasmas in the Earth's inner magnetosphere are also discussed in this paper.
title: Infundibulo-neurohypophysitis in a pediatric patient
Creators: name: DÍAZ MORENO, ALEJANDRO
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Neuroradiology
subject: Neuroradiology brain
subject: MR
subject: Clinical Cases

description: Clinical History: A 4-year-old girl with intermittent headache, polydipsia, polyuria and nocturia of very dilute and hypotonic urine in the past 4 weeks. No relevant personal or family history. She was admitted to the pediatric unit for further examination. MRI of the brain was performed.

description: 4 years, female
Heartfield im Zentralbüro für Kunstausstellungen (Centralne Biuro Wystaw Artystycznych) in Warschau (1964)
Creators: name: Świtek, Gabriela
Publisher: name: Humboldt-Universität zu Berlin
Year: 2018
Subjects: subject: John Heartfield, DDR, Polen, Deutschland, Ausstellung, Rezeption, Dada, Kunstpolitik
subject: 700 Künste

description: The paper explores some political and art-historical aspects of the exhibition Unfortunately Still Current: John Heartfield’s Photomontages (GDR) shown in the Central Office for Art Exhibitions in Warsaw (February 1964). While Heartfield’s works of the 1920s and the 1930s are still subject to new challenging interpretations, less analysed is their post-war reception including the travelling exhibitions of the 1960s. On the one hand, the Warsaw show was one of Heartfield’s post-war exhibitions which travelled to Czechoslovakia, Hungary, Italy, Sweden or Great Britain. On the other hand, the presentation of his work in the Central Office for Art Exhibitions, the largest state gallery in the Polish People’s Republic, was part of a geopolitically planned art exchange between Poland and other countries behind the Iron Curtain. What is discussed in this context are some differences between the exhibitions of contemporary art from the German Democratic Republic and the Federal Republic of Germany organized in Warsaw in the 1950s and the 1960s. The 1964 Warsaw exhibition rhetoric is confronted with some paragraphs of Wieland Herzfelde’s biography of his brother John Heartfield: Leben und Werk (originally published in 1962 and reedited twice in the 1970s) as well as with Heartfield’s reception in Poland due to his artistic contacts with Mieczysław Berman. The validity of Heartfield’s exhibition is also discussed in relation to Dadaism’s revival in the 1960s, marked with the publication of Hans Richter’s DaDa – Kunst und Antikunst in 1964.
Principles of Open Source Witchcraft: emic perspectives on freedom of knowledge
Creators: name: Fitzpatrick, Joanne
Publisher: name: Zenodo
Year: 2022
Subjects: library
information
library science
information science
librarianship
open access
open source
witchcraft
paganism
occult
magick

description: Paper presented at Magickal Women Conference Sat 15th Oct 2022 Includes 10 'Principles of Open Source Witchcraft' devised from examining key open research frameworks and applying them to practices in witchcraft and magick Also includes a link to a Miro diagram that maps considerations in this area https://miro.com/app/board/uXjVPcqhGek=/ Abstract: https://www.magickalwomenconference.com/joanne-fitzpatrick-2022 The tightrope between saliency and secrecy is a complex one for practitioners of Contemporary Paganism and Western Esoteric traditions. Previously only concerned with doing a certain degree of public work to allow access points for new adherents: tradition, liturgy and knowledge are generally closed and protected by oaths. Borrowing the ‘open source’ term from software development, several groups are experimenting with more open practices, such as non-initiatory structures or online publishing of original liturgy, and this activity is increasing in pace. There is certainly appetite for open access material, evidenced in the prolific downloading of pirated eBooks in the discipline, grown out of the as yet unsubstantiated myth that the most commonly stolen items from libraries and archives are occult texts. There are perceived and actual implications of removing kept gates from occult knowledge, and applying information science and open research frameworks to work by Pagan and Occult practitioners provides insight and a method of doing this well. Conclusions are offered to support open source alternative religion and spirituality as a positive force. In many ways, avoidance or poor application of open working can cause problems with the resilience, visibility and respectability of Pagan and Occult traditions.
description: {"references": ["https://doi.org/10.1558/pome.22512"]}
Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells.
Creators: name: Nakanoh, Shota
name: Kadiwala, Juned
name: Pinte, Laetitia
name: Morell, Carola Maria
name: Lenaerts, An-Sofie
name: Vallier, Ludovic
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research Article
Biology and life sciences
Medicine and health sciences
Research and analysis methods

description: Acknowledgements: We thank Stephany Brown for the technical supports, Dr. Toshihiko Fujimori for discussion and Fatima Lugtu for English proofreading.
description: Funder: European Research Council
description: Funder: Cambridge Hospitals National Institute for Health Research Biomedical Research Center
description: Funder: National Centre for the Replacement Refinement and Reduction of Animals in Research; funder-id: http://dx.doi.org/10.13039/501100010757
description: Funder: Wellcome Trust and Medical Research Council - Cambridge Stem Cell Institute
description: RB is a well-known cell cycle regulator controlling the G1 checkpoint. Previous reports have suggested that it can influence cell fate decisions not only by regulating cell proliferation and survival but also by interacting with transcription factors and epigenetic modifiers. However, the functional redundancy of RB family proteins (RB, RBL1 and RBL2) renders it difficult to investigate their roles during early development, especially in human. Here, we address this problem by generating human embryonic stem cells lacking RB family proteins. To achieve this goal, we first introduced frameshift mutations in RBL1 and RBL2 genes using the CRISPR/Cas9 technology, and then integrated the shRNA-expression cassette to knockdown RB upon tetracycline treatment. The resulting RBL1/2_dKO+RB_iKD cells remain pluripotent and efficiently differentiate into the primary germ layers in vitro even in the absence of the RB family proteins. In contrast, we observed that subsequent differentiation into foregut endoderm was impaired without the expression of RB, RBL1 and RBL2. Thus, it is suggested that RB proteins are dispensable for the maintenance and acquisition of cell identities during early development, but they are essential to generate advanced derivatives after the formation of primary germ layers. These results also indicate that our RBL1/2_dKO+RB_iKD cell lines are useful to depict the detailed molecular roles of RB family proteins in the maintenance and generation of various cell types accessible from human pluripotent stem cells.
Einleitung
Creators: name: Wenninger, Regina
name: Wienert, Annika
Publisher: name: Humboldt-Universität zu Berlin
Year: 2018
Subjects: subject: histoire croisée, Kunstgeschichte, Deutschland, Polen, Kunsthistoriographie, Denkmalpflege, Ausstellung, Kulturpolitik
subject: 700 Künste

description: Verflechtung und Abgrenzung. Polnisch-deutsche Perspektiven in der Kunstgeschichte seit 1945. Einführung Die vorliegende Themenausgabe beruht auf ausgewählten Beiträgen einer gleichnamigen Tagung, die im November 2017 im Deutschen Historischen Institut Warschau stattfand. Ausgehend vom Konzept der histoire croisée (Verflechtungsgeschichte) setzten sich die Teilnehmerinnen und Teilnehmer zum Ziel, verbindende und trennende Aspekte der Kunstgeschichte in Polen und Deutschland zu analysieren, wobei der Fokus auf dem 20. und 21. Jahrhundert lag. Dabei konnten methodische Problemstellungen der histoire croisée anhand eines breiten Themenspektrums erörtert werden. In der Einführung skizzieren die Autorinnen zunächst den methodischen Ansatz der histoire croisée. Im Anschluss daran werden verschiedene Aspekte kritisch diskutiert und auf das Themenfeld der deutsch-polnischen Kunstgeschichte bezogen. Zwei Fragekomplexe werden dabei herausgearbeitet: Zunächst geht es um die Kritik der histoire croisée am nationalen Paradigma der Geschichtswissenschaften. Andererseits wird erörtert, ob der Ansatz nicht negative Pendants der Verflechtung vernachlässigt – Phänomene der Abwehr, Abgrenzung und Ent-flechtung. An diese Überlegungen schließt sich ein Resümee der Diskussionen an, die auf der Tagung ausgehend von den präsentierten Fallstudien geführt wurden. Hierbei steht die Frage im Vordergrund, was die histoire croisée der Kunstgeschichte als Fach Neues hinzufügen kann. Abschließend werden die Beiträge des Heftes vorgestellt, wobei jeweils zwei Beiträge unter einer inhaltlichen Klammer in Bezug zueinander gesetzt werden. Unter dem Titel „Kunstausstellungen und ihre Kontexte“ finden sich der Beitrag von Gabriela Świtek zu Ausstellungen von John Heartfield in Polen sowie Marta Smolińskas Analyse aktueller Kunstprojekte, die sich mit polnisch-deutschen Grenz- und Erinnerungsorten auseinandersetzen. Die Aspekte „bilateral und international“ finden sich in den Beiträgen von Julia Röttjer zur UNESCO-Kommission und von Angelika Weißbach zur DDR-Beteiligung an der Internationale Biennale der Grafik in Krakau. „Schwieriges Erbe“ nehmen Nawojka Cieślińska-Lobkowicz und Aleksandra Paradowska in diachroner Perspektive in den Blick; erstere beschäftigt sich mit der Provenienzforschung, letztere mit dem Umgang mit dem architektonischen Erbe des Nationalsozialismus in Westpolen.
Approximate message passing with spectral initialization for generalized linear models*
Creators: name: Mondelli, Marco
name: Venkataramanan, Ramji
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Paper
Machine Learning 2022
machine learning
message-passing algorithms
statistical inference
learning theory

description: Abstract We consider the problem of estimating a signal from measurements obtained via a generalized linear model. We focus on estimators based on approximate message passing (AMP), a family of iterative algorithms with many appealing features: the performance of AMP in the high-dimensional limit can be succinctly characterized under suitable model assumptions; AMP can also be tailored to the empirical distribution of the signal entries, and for a wide class of estimation problems, AMP is conjectured to be optimal among all polynomial-time algorithms. However, a major issue of AMP is that in many models (such as phase retrieval), it requires an initialization correlated with the ground-truth signal and independent from the measurement matrix. Assuming that such an initialization is available is typically not realistic. In this paper, we solve this problem by proposing an AMP algorithm initialized with a spectral estimator. With such an initialization, the standard AMP analysis fails since the spectral estimator depends in a complicated way on the design matrix. Our main contribution is a rigorous characterization of the performance of AMP with spectral initialization in the high-dimensional limit. The key technical idea is to define and analyze a two-phase artificial AMP algorithm that first produces the spectral estimator, and then closely approximates the iterates of the true AMP. We also provide numerical results that demonstrate the validity of the proposed approach.
The application of an age adjusted D-dimer threshold to rule out suspected venous thromboembolism (VTE) in an emergency department setting: a retrospective diagnostic cohort study.
Creators: name: Barrett, Liam
name: Jones, Tom
name: Horner, Daniel
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research
Venous thromboembolism (VTE)
D-dimer
DVT
PE
Emergency medicine
Compression Ultrasonography

description: BACKGROUND: Venous Thromboembolic disease (VTE) poses a diagnostic challenge for clinicians in acute care. Over reliance on reference standard investigations can lead to over treatment and potential harm. We sought to evaluate the pragmatic performance and implications of using an age adjusted D-dimer (AADD) strategy to rule out VTE in patients with suspected disease attending an emergency department (ED) setting. We aimed to determine diagnostic test characteristics and assess whether this strategy would result in proportional imaging reduction and potential cost savings. METHODS: Design: Single centre retrospective diagnostic cohort study. All patients > 50 years old evaluated for possible VTE who presented to the emergency department over a consecutive 12-month period between January and December 2016 with a positive D-dimer result. Clinical assessment records and reference standard imaging results were followed up by multiple independent adjudicators and coded as VTE positive or negative. RESULTS: During the study period, there were 2132 positive D-dimer results. One thousand two hundred thirty-six patients received reference standard investigations. A total increase of 314/1236 (25.1%) results would have been coded as true negatives as opposed to false positive if the AADD cut off point had been applied, with 314 reference standard tests subsequently avoided. The AADD cut off had comparable sensitivity to the current cut off despite this increase in specificity; sensitivities for the diagnosis of DVT were 99.28% (95% CI 96.06-99.98%) and 97.72% for PE (95% CI 91.94% to 97.72). There were 3 false negative results using the AADD strategy. CONCLUSIONS: In patients with suspected VTE with a low or moderate pre-test probability, the application of AADD appears to increase the proportion of patients in which VTE can be excluded without the need for reference standard imaging. This management strategy is likely to be associated with substantial reduction in anticoagulation treatment, investigations and cost/time savings.
Bilateral im universellen Rahmen? Polnische und deutsche Denkmalpfege in internationalen Organisationen
Creators: name: Röttjer, Julia
Publisher: name: Humboldt-Universität zu Berlin
Year: 2018
Subjects: subject: UNESCO, ICOMOS, Polen, Deutschland, Kunstpolitik, Denkmalpflege
subject: 700 Künste

description: In internationalen Organisationen wie UNESCO und ICOMOS arbeiteten polnische und west- wie ostdeutsche Denkmalpfleger eng zusammen. Der Beitrag analysiert, wie sich die spannungsreichen bilateralen Konstellationen im Kontext dieser internationalen Gremien ausprägten: Wo kam es zu Abgrenzung oder Annäherung, Konflikten oder Allianzen und welche Auswirkungen hatte dies auf denkmalpflegerische Konzepte? Deutlich wird dabei auch, dass nationale Kategorien eine wichtige Bezugsgröße in diesen Aushandlungsprozessen bildeten, wenn sie auch immer wieder überlagert wurden durch transnationale Konzepte wie Ost und West oder Europa. Aus verflechtungsgeschichtlicher Perspektive gilt es jene Bezugnahmen kritisch zu hinterfragen, ohne jedoch ihre Funktion im untersuchten historischen Kontext aus dem Blick zu verlieren.
A Shigella sonnei clone with extensive drug resistance associated with waterborne outbreaks in China.
Creators: name: Qiu, Shaofu
name: Liu, Kangkang
name: Yang, Chaojie
name: Xiang, Ying
name: Min, Kaiyuan
name: Zhu, Kunpeng
name: Liu, Hongbo
name: Du, Xinying
name: Yang, Mingjuan
name: Wang, Ligui
name: Sun, Yong
name: Zhou, Haijian
name: Mahe, Muti
name: Zhao, Jiayong
name: Li, Shijun
name: Yu, Deshan
name: Hawkey, Jane
name: Holt, Kathryn E
name: Baker, Stephen
name: Yang, Juntao
name: Xu, Xuebin
name: Song, Hongbin
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/326/41/1470
/631/326/1762
/631/326/22/1290
/631/326/22/1434
/38/23
/38/77
/45/43
/45/88
article

description: Funder: National Key R&D Program of China (grant number 2017YFC1600100) National Key Program for Infectious Diseases of China (no. 2012ZX10004215) National Nature Science Foundation of China (no. 82173580) National Nature Science Foundation of China (no. 81872678) Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2021-I2M-1-044)
description: Antimicrobial resistance of Shigella sonnei has become a global concern. Here, we report a phylogenetic group of S. sonnei with extensive drug resistance, including a combination of multidrug resistance, coresistance to ceftriaxone and azithromycin (cefRaziR), reduced susceptibility to fluoroquinolones, and even colistin resistance (colR). This distinct clone caused six waterborne shigellosis outbreaks in China from 2015 to 2020. We collect 155 outbreak isolates and 152 sporadic isolates. The cefRaziR isolates, including outbreak strains, are mainly distributed in a distinct clade located in global Lineage III. The outbreak strains form a recently derived monophyletic group that may have emerged circa 2010. The cefRaziR and colR phenotypes are attributed to the acquisition of different plasmids, particularly the IncB/O/K/Z plasmid coharboring the blaCTX-M-14, mphA, aac(3)-IId, dfrA17, aadA5, and sul1 genes and the IncI2 plasmid with an mcr-1 gene. Genetic analyses identify 92 accessory genes and 60 single-nucleotide polymorphisms associated with the cefRaziR phenotype. Surveillance of this clone is required to determine its dissemination and threat to global public health.
title: Regulation of beta2-adrenoceptors by steroid hormones in asthma
Creators: name: Tan, Kia Soong
Publisher: name: University of Glasgow
Year: 1998
Subjects: subject: Pharmacology.

description: Previous studies have demonstrated the facilitatory effects of corticosteroids on the beta2-adrenoceptor (beta2-AR). Tolerance or subsensitivity with regular beta2-agonist use is of concern m asthma therapy. As corticosteroids and beta2-agonists are often prescribed together, the aim of these studies was to investigate their mteraction on beta2-AR function. Our initial study showed that despite taking inhaled corticosteroids, asthma patients developed bronchodilator and systemic beta2-AR subsensitivity following regular formoterol use. Administration of systemic corticosteroid rapidly restored beta2-AR responsiveness. This reversibility did not appear to be related to beta2-AR polymorphism. However, the development of formoterol-induced bronchodilator subsensidvity was influenced by beta2-AR polymorphism, with glycine 16 homozygous patients developing greater desensitisation than those homozygous for arginine 16. We further demonstrated that inhaled corticosteroids failed to prevent the development of tolerance to the bronchoprotective effects of formoterol against methacholine and AMP, irrespective of formoterol dose and dosing frequency. beta2-AR polymorphism did not appear to influence the development of bronchoprotective tolerance, in contrast to bronchodilator tolerance. Unlike systemic corticosteroid, high-dose inhaled corticosteroid, in single and repeated doses, showed no significant facilitatory effect on lymphocyte beta2-AR parameters. In contrast, we demonstrated that low-dose systemic corticosteroid protected against the development of beta2-AR subsensitivity induced by regular formoterol treatment. Female sex steroid hormones also influence beta2-AR function. Indeed, abnormal beta2-AR regulation has been postulated as a cause of premenstrual asthma. We found that normal cyclical regulation of beta2-AR function was lost in female asthmatic patients. In addition, there was greater airway hyperresponsiveness to AMP during the premenstrual period compared to the follicular phase. Our studies showed that exogenous progesterone, but not oestradiol, had facilitatory effects on lymphocyte beta2- AR function m normal females. In contrast, exogenous progesterone had a 'paradoxical' down-regulating and desensitising effect on beta2-AR function in female asthmatic patients. Unlike those with natural menstrual cycles, female asthmatics taking the oral contraceptive pill had attenuated cyclical changes in airway hyperresponsiveness and diurnal peak flow rates. We therefore conclude that corticosteroids have significant facilitatory effects on beta2- AR function m asthma. Our findings also suggest that there may be abnormal hormonal regulation of beta2-AR in female asthma patients. Further studies examining the facilitatory effects of inhaled corticosteroid on beta2-AR function m asthma are indicated. Research into the role of exogenous sex hormones on beta2-AR function m premenstrual asthma, pregnancy and the menopause is also necessary.
Co-designed mini-games for children with visual impairment: a pilot study on their usability.
Creators: name: Battistin, Tiziana
name: Dalla Pozza, Nadir
name: Trentin, Silvia
name: Volpin, Giovanni
name: Franceschini, Andrea
name: Rodà, Antonio
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Human-computer Interaction
Serious Games
Children With Visual Impairment
Large Scale Interactive Environment

description: UNLABELLED: Digital games aimed at improving cognitive and/or motor-sensory skills need to be carefully designed to take into account the characteristics and needs of particular categories of users. Several novel mini-games explicitly aimed at children with visual impairment (VI) were co-designed by a multidisciplinary team which involved computer engineers and a therapy team from the Robert Hollman Foundation (Padova, Italy). These games are played by children moving within a large-scale interactive environment - i.e., a floor portion placed under a motion capture system capable of tracking one or more people - with the game linking the players movements to the audio and visual output to produce meaningful interactions. We report on a pilot study of the usability of the system involving 11 children with VI. The results allowed us to improve the system and to define a set of guidelines useful for designers and developers of similar systems. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11042-022-13665-7.
Characterizing palliative care needs in people with or at risk of developing diabetic foot ulcers.
Creators: name: Mendonça, Liliane
name: Antunes, Bárbara
name: Rigor, Joana
name: Martins-Mendes, Daniela
name: Monteiro-Soares, Matilde
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Recent challenges and future opportunities in caring for patients with diabetic foot disease
cohort analysis
chronic illness
diabetes
diabetic foot
Palliative care
wound care

description: Peer reviewed: True
description: AIMS: Diabetic foot ulcers (DFUs) have a significant impact on a patient's quality of life and life expectancy, with mortality rates comparable with malignant diseases. However, there is a lack of data regarding palliative care needs in this population. We aimed to characterize palliative care needs in people under diabetic foot surveillance using the Integrated Palliative care Outcome Scale (IPOS) and EuroQol-5D three-level version (EQ-5D-3L) and to assess differences between those with and without a DFU. METHODS: We conducted a cross-sectional study with consecutive sampling inclusion of patients followed in a tertiary hospital's Diabetic Foot Clinic between February and October 2019 with (n = 20) and without (n = 42) active DFU. RESULTS: The most frequent symptoms encountered were pain, weakness or lack of energy, sore or dry mouth and drowsiness. Patients with an active DFU were significantly more likely to report feeling anxious or worried in comparison with those without (95% versus 55%, p = 0.002). Only 10% of the participants with an active DFU said that they were always able to share how they felt with family and friends as much as they wanted in comparison with 45% of those without (p = 0.006). CONCLUSION: Our study identified palliative care needs in patients under diabetic foot surveillance with and without DFU, including a significant presence of physical symptoms. Patients in both groups showed signs of emotional/psychological distress, with a higher manifestation in patients with DFU. To the best of our knowledge, this is the first study addressing and characterizing palliative care needs in this population.
MPEC 2023-L68 : 2023 LA1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 LA1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Bank Muamalat Indonesia: Mapping Research Topics using Library Research
Creators: name: Andresta, Tara
name: Budianto, Eka Wahyu Hestya
name: Dewi, Nindi Dwi Tetria
Publisher: name: Zenodo
Year: 2023

description: This research aims to map research topics surrounding Bank Muamalat Indonesia using a qualitative approach, which is in the nature of a library research. The data collection technique is: first, open the Perish/Harzing software, then search for journals based on the title words category with the key word " Bank Muamalat Indonesia " within the entire year period. Second, collect journal title data in Microsoft Excel, and identify duplicate journal titles. Third, download files in RIS (Research Information Systems) and PDF (Portable Document Format) format from all journals for which data has been collected. Fourth, enter the RIS data file into Mendeley software Desktop. Data analysis technique by mapping research topics around Bank Muamalat Indonesia based on the journals that have been collected. The research results show that There are 7 mapping research topics using literature studies about Bank Muamalat Indonesia, namely: (1) Financial performance; (2) Employee performance; (3) Customer behavior; (4) Financing/credit products; (5) Savings/deposit products; (6) Accounting treatment; and (7) Other issues. The implication and contribution of this research is the mapping of research topics surrounding Bank Muamalat Indonesia, both frequently and rarely researched by researchers, so that other researchers can find out the gaps in research on this topic.
Supplementary material to World Mycotoxin Journal article: Assessment of agricultural practices by Ethiopian women farmers: existence of gender disparities in access to mycotoxins training
Creators: name: Cervini, Carla
name: Abegaz, B.
name: Mohammed, A.
name: Elias, R.
name: Medina, A.
name: Gebre, K.
name: Verheecke-Vaessen, C.
Publisher: name: Brill Online
Year: 2023
Subjects: Crop and pasture protection (incl. pests, diseases and weeds)
Food safety, traceability, certification and authenticity
Toxicology (incl. clinical toxicology)

description: Ethiopia is one of the countries with the lowest gender-equality performance in sub-Saharan Africa being ranked 121/134 in terms of the magnitude and scope of gender disparities by the United Nations Women’s Organisation. Within the farming communities, women represent 70% of the labour force, but they are neglected from accessing training events run by Ethiopian Universities (e.g. Haramaya University). A survey to assess the existence of gender disparities among Ethiopian women farmers with respect to agricultural labour and mycotoxins knowledge was conducted on three hundred and forty-nine women from the Oromia and Amhara regions. A higher illiteracy rate was found in women compared to men from both Oromia and Amhara regions. Women played a key role in agricultural activities while having limited access to modern technologies compared to their male counterparts. Women were mainly responsible for sorting spoiled crops. Especially in Amhara, these were intended for home consumption, representing a serious health risk for local people. Overall, women from Amhara were more aware than women from Oromia about what mycotoxins are (e.g. aflatoxins), their impact and risk of occurrence in crops. Women in Amhara were also more intended to act towards mycotoxins in the future compared to women from Oromia. Only 0.24% of women have previously attended a training on mycotoxins. The radio seemed to be the most efficient way to deliver training to Ethiopian women farmers from these regions. Mycotoxins trainings were the second option of choice by all women surveyed. Such findings clearly stated the existence of gender inequality in the two Ethiopian regions considered. Empower women’s knowledge about mycotoxins will not only benefit agricultural income and the national economy, but it will also provide women the recognition they equally deserve alongside their male counterparts in future agricultural training programs and interventions.
Arc Plasma Torch Modeling
Creators: name: Trelles, J. P.
name: Chazelas, C.
name: Vardelle, A.
name: Heberlein, J. V. R.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Arc plasma torches are the primary components of various industrial thermal plasma processes involving plasma spraying, metal cutting and welding, thermal plasma CVD, metal melting and remelting, waste treatment and gas production. They are relatively simple devices whose operation implies intricate thermal, chemical, electrical, and fluid dynamics phenomena. Modeling may be used as a means to better understand the physical processes involved in their operation. This paper presents an overview of the main aspects involved in the modeling of DC arc plasma torches: the mathematical models including thermodynamic and chemical non-equilibrium models, turbulent and radiative transport, thermodynamic and transport property calculation, boundary conditions and arc reattachment models. It focuses on the conventional plasma torches used for plasma spraying that include a hot-cathode and a nozzle anode.
Ramsey interferometry using the Zeeman sublevels in a spin-2 Bose gas
Creators: name: Sadgrove, M.
name: Eto, Y.
name: Sekine, S.
name: Suzuki, H.
name: Hirano, T.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We perform atom interferometry using the Zeeman sublevels of a spin-2 Bose-Einstein condensate of $^{87}$Rb. The observed fringes are strongly peaked, and fringe repetition rates higher than the fundamental Ramsey frequency are found in agreement with a simple theory based on spin rotations. With a suitable choice of initial states, the interferometer could function as a useful tool for magnetometry and studies of spinor dynamics in general.
Quantum cosmology from the de Broglie-Bohm perspective
Creators: name: Pinto-Neto, N.
name: Fabris, J. C.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We review the main results that have been obtained in quantum cosmology from the perspective of the de Broglie-Bohm quantum theory. As it is a dynamical theory of assumed objectively real trajectories in the configuration space of the physical system under investigation, this quantum theory is not essentially probabilistic and dispenses the collapse postulate, turning it suitable to be applied to cosmology. In the framework of minisuperspace models, we show how quantum cosmological effects in the de-Broglie-Bohm's approach can avoid the initial singularity, and isotropize the Universe. We then extend minisuperspace in order to include linear cosmological perturbations. We present the main equations which govern the dynamics of quantum cosmological perturbations evolving in non-singular quantum cosmological backgrounds, and calculate some of their observational consequences. These results are not known how to be obtained in other approaches to quantum theory. In the general case of full superspace, we enumerate the possible structures of quantum space and time that emerge from the de Broglie-Bohm picture. Finally, we compare some of the results coming from the de Broglie-Bohm theory with other approaches, and discuss the physical reasons for some discrepancies that occur.
description: Latex file, 75 pages, 3 figures in eps format. To appear in CQG as an invited Topical Review