cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Chaos in high-dimensional dynamical systems
Creators: name: Ispolatov, Iaroslav
name: Doebeli, Michael
name: Allende, Sebastian
name: Madhok, Vaibhav
Publisher: name: arXiv
Year: 2014
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: For general dissipative dynamical systems we study what fraction of solutions exhibit chaotic behavior depending on the dimensionality $d$ of the phase space. We find that a system of $d$ globally coupled ODE's with quadratic and cubic non-linearities with random coefficients and initial conditions, the probability of a trajectory to be chaotic increases universally from $\sim 10^{-5} - 10^{-4}$ for $d=3$ to essentially one for $d\sim 50$. In the limit of large $d$, the invariant measure of the dynamical systems exhibits universal scaling that depends on the degree of non-linearity but does not depend on the choice of coefficients, and the largest Lyapunov exponent converges to a universal scaling limit. Using statistical arguments, we provide analytical explanations for the observed scaling and for the probability of chaos.
description: 5 pages, 3 figures
TOWARDS A UNIFIED REFERENCE ARCHITECTURE IN AECOO INDUSTRY
Creators: name: Several Authors
Publisher: name: Zenodo
Year: 2023

description: Nowadays, discussion across the construction industry about moving away from silos in different phases of the design and construction process has become a hot topic. Utilising key project data through integrated systems and technologies in an effort to eliminate common problems such as re-entry of data or data redundancy is a matter of traceability and trustworthiness, hence controlling the risks. In order to achieve such an integrated information flow across the life cycle of an asset, data interoperability is extremely important in the AECOO (Architecture, Engineering and Construction, Owner and Operator) industry as the industry encounters a lot of complexity like many stakeholders, one-off projects and an ever-changing environment.
Archiv der Max-Planck-Gesellschaft, Berlin
Creators: name: Giltaij, Jacob
name: Tuori, Kaius
Publisher: name: Zenodo
Year: 2018
Subjects: Helmut Coing

description: Archival notes from Archiv der Max-Planck-Gesellschaft zu Berlin, Abteilung III, Repositur 103. Jacob Giltaij: Documents from the Nachlass Helmut Coing at the Archiv der Max-Planck-Gesellschaft in Berlin. Kaius Tuori: The papers of Coing beginning from 1963, when he was selected director of the MPIeR. Papers were handed over to the archive between 2010-2012. Contains his unpublished autobiography.
CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: NF-Y binds a CCAAT motif found in many eukaryotic polymerase II-dependent promoters. In the HLA-DRA promoter it has been demonstrated that stereo-specific alignment between this motif and the upstream elements X1 and X2 is required for activation. To study the underlying mechanism for this requirement, a panel of transfected cell lines that maintained integrated, wild-type and mutant promoters were analyzed by in vivo genomic footprinting. Cell lines harboring a mutated CCAAT element exhibited a loss of interactions at the CCAAT site, as expected, and no transcriptional activity.
Canonical Formulation of $O(N)$ Vector/Higher Spin Correspondence
Creators: name: Koch, Robert de Mello
name: Jevicki, Antal
name: Rodrigues, João P.
name: Yoon, Junggi
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the canonical structure of the collective formulation of Vector Model/Higher Spin Duality in AdS$_4$. This involves a construction of bulk AdS Higher Spin fields through a time-like bi-local Map, with a Hamiltonian and canonical structure which are established to all orders in $1/N$.
description: 24 pages; v2: minor changes, references added, version to be submitted to J. Phys. A; v3: reference added and typos corrected. Minor improved. An appendix about algebra of bi-local operators added
Archiv der Ludwig-Maximilians-Universität, Munich
Creators: name: Giltaij, Jacob
Publisher: name: Zenodo
Year: 2018
Subjects: Paul Koschaker

description: Archival notes from Universitätsarchiv München. Universitätsarchiv München, Personalakte der Juristischen Fakultät, L-IX-037: Personal documents regarding Koschaker at the law faculty of the LMU. Universitätsarchiv München, Personalakte des akademischen Senats, Koschaker E-II-02093: Documents of the senate of the LMU regarding Paul Koschaker.
MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Pheromone-stimulated yeast cells and haploid gpa1 deletion mutants arrest their cell cycle in G1. Overexpression of a novel gene called MSG5 suppresses this inhibition of cell division. Loss of MSG5 function leads to a diminished adaptive response to pheromone. Genetic analysis indicates that MSG5 acts at a stage where the protein kinases STE7 and FUS3 function to transmit the pheromone-induced signal. Since loss of MSG5 function causes an increase in FUS3 enzyme activity but not STE7 activity, we propose that MSG5 impinges on the pathway at FUS3. Sequence analysis suggests that MSG5 encodes a protein tyrosine phosphatase. This is supported by the finding that recombinant MSG5 has phosphatase activity in vitro and is able to inactivate autophosphorylated FUS3. Thus MSG5 might stimulate recovery from pheromone by regulating the phosphorylation state of FUS3.
Exploring the Anomalous Higgs-top Couplings
Creators: name: Khatibi, Sara
name: Najafabadi, Mojtaba Mohammadi
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Top quark with its large Yukawa coupling is crucially important to explore TeV scale physics. Therefore, the study of Higgs-top sector is highly motivated to look for any deviations from the standard model predictions. The most general lowest order Lagrangian for the Higgs-top Yukawa coupling has scalar ($κ$) and pseudoscalar ($\tildeκ$) components. Currently, these couplings are constrained indirectly using the present experimental limits on the Higgs-$γ$-$γ$ and Higgs-gluon-gluon couplings. Furthermore, stronger bounds on $κ$ and $\tildeκ$ are obtained using the limits on the electric dipole moments (EDM). In this work, we propose an asymmetry-like observable $O_ϕ$ in $t\bar{t}H$ production at the LHC to probe the Higgs-top coupling and to distinguish between the scalar and pseudoscalar components. We also show that the presence of the pseudoscalar component in the Higgs-top Yukawa coupling leads to a sizeable value for the top quark EDM. It is shown that a limit of $10^{-19}$ e.cm, which is achievable by the future $e^{-}e^{+}$ collider, allows us to exclude a significant region in the $(κ,\tildeκ)$ plane.
description: 15 pages, 8 figures
РОССИЯ ФЕДЕРАЦИЯСИ ФЕДЕРАЛ ҚЎШИНЛАРИНИНГ ЖАНГОВАР ҲАРАКАТЛАРДА ФРОНТ ОРТИ ТАЪМИНОТИ ВА АХЛОҚИЙ-РУҲИЙ ТАЪМИНОТНИ ТАШКИЛЛАШТИРИШ ТАЖРИБАСИ
Creators: name: Бекназаров, Асқар
Publisher: name: Zenodo
Year: 2023

description: Ушбу мақолада Росссий федерацияси Қуролли Кучлари федерал қўшинларининг Шимолий Кавказ минтақасида жанговар ҳаракатлардаги фронт орти таъминотини ва ахлоқий-руҳий таъминотни ташкиллаштириш бўйича тажрибалари, жанговар ҳаракатларда фронт орти таъминотини ҳамда ахлоқий-руҳий таъминотни ташкиллшириш бўйича камчиликлар ва ташкиллаштириш ва олиб боришнинг таҳлили, хулосалари хусусида сўз юритилади.
Universality far from equilibrium: From superfluid Bose gases to heavy-ion collisions
Creators: name: Berges, J.
name: Boguslavski, K.
name: Schlichting, S.
name: Venugopalan, R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Isolated quantum systems in extreme conditions can exhibit unusually large occupancies per mode. This over-population gives rise to new universality classes of many-body systems far from equilibrium. We present theoretical evidence that important aspects of non-Abelian plasmas in the ultra-relativistic limit admit a dual description in terms of a Bose condensed scalar field theory.
description: 5 pages, 5 figures, PRL version, minor changes
Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends.
Creators: name: Endow, S
name: Kang, S
name: Rose, M
name: Satterwhite, L
name: Salmon, E
name: Skeen, V
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Mutants of the yeast Kar3 protein are defective in nuclear fusion, or karyogamy, during mating and show slow mitotic growth, indicating a requirement for the protein both during mating and in mitosis. DNA sequence analysis predicts that Kar3 is a microtubule motor protein related to kinesin, but with the motor domain at the C-terminus of the protein rather than the N-terminus as in kinesin heavy chain. We have expressed Kar3 as a fusion protein with glutathione S-transferase (GST) and determined the in vitro motility properties of the bacterially expressed protein. The GST-Kar3 fusion protein bound to a coverslip translocates microtubules in gliding assays with a velocity of 1-2 microns/min and moves towards microtubule minus ends, unlike kinesin but like kinesin-related Drosophila ncd. Taxol-stabilized microtubules bound to GST-Kar3 on a coverslip shorten as they glide, resulting in faster lagging end, than leading end, velocities. Comparison of lagging and leading end velocities with velocities of asymmetrical axoneme-microtubule complexes indicates that microtubules shorten preferentially from the lagging or minus ends. The minus end-directed translocation and microtubule bundling of GST-Kar3 is consistent with models in which the Kar3 protein crosslinks internuclear microtubules and mediates nuclear fusion by moving towards microtubule minus ends, pulling the two nuclei together. In mitotic cells, the minus end motility of Kar3 could move chromosomes polewards, either by attaching to kinetochores and moving them polewards along microtubules, or by attaching to kinetochore microtubules and pulling them polewards along other polar microtubules.(ABSTRACT TRUNCATED AT 250 WORDS)
Detecting Malicious Domains Using Statistical Internationalized Domain Name Features in Top Level Domains
Creators: name: Almarzooqi, Alshaima
name: Mahmoud, Jawahir
name: Alzaabi, Bayena
name: Ghebremichael, Arsiema
name: Aldwairi, Monther
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: The Domain Name System (DNS) is a core Internet service that translates domain names into IP addresses. It is a distributed database and protocol with many known weaknesses that subject to countless attacks including spoofing attacks, botnets, and domain name registrations. Still, the debate between security and privacy is continuing, that is DNS over TLS or HTTP, and the lack of adoption of DNS security extensions, put users at risk. Consequently, the security of domain names and characterizing malicious websites is becoming a priority. This paper analyzes the difference between the malicious and the normal domain names and uses Python to extract various malicious DNS identifying characteristics. In addition, the paper contributes two categories of features that suppers Internationalized Domain Names and scans domain system using five tools to give it a rating. The overall accuracy of the Random Forest Classifier was 95.6%.
Fast inversion of solar Ca II spectra
Creators: name: Beck, C.
name: Choudhary, D. Prasad
name: Rezaei, R.
name: Louis, R. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a fast (<< 1 s per profile) inversion code for solar Ca II lines. The code uses an archive of spectra that are synthesized prior to the inversion under the assumption of local thermodynamic equilibrium (LTE). We show that it can be successfully applied to spectrograph data or more sparsely sampled spectra from two-dimensional spectrometers. From a comparison to a non-LTE inversion of the same set of spectra, we derive a first-order non-LTE correction to the temperature stratifications derived in the LTE approach. The correction factor is close to unity up to log tau ~ -3 and increases to values of 2.5 and 4 at log tau = -6 in the quiet Sun and the umbra, respectively.
description: 8 pages, 10 figures, accepted for publication in ApJ; version updated for an error in the references
Seaweeds: A Sustainable Revolution in Livestock Feed
Creators: name: Adis Mirel Ahmed
Publisher: name: The Science world a Monthly e magazine
Year: 2024

description: As the global population is approaching the 9 billion mark by 2050, there is an urgent need to enhance food production by 70%, with a particular focus on sustainable practices in the livestock industry. This article explores the potential of seaweeds as innovative and eco-friendly feed additives for livestock. Drawing on historical practices dating back thousands of years and recent research findings, this article provides an in-depth understanding of seaweeds, categorizing them into green, red, and brown algae. The nutritional attributes of seaweeds including macronutrients and micronutrients are highlighted presenting a diverse and comprehensive profile. Studies revealed their positive impact on animal nutrition, performance, and health, showcasing antibacterial and antioxidant properties. Seaweeds emerge as a game-changer for sustainable and nutritious livestock feed, signalling a crucial shift toward resilience and eco-conscious practices in animal production. Ongoing research should optimise inclusion levels and processing methods for maximal benefit.
Westfälische Wilhelms-Universität, Münster
Creators: name: Beggio, Tommaso
Publisher: name: Zenodo
Year: 2018
Subjects: Paul Koschaker
C. Bradford Welles

description: Archival notes from Westfälische Wilhelms-Universität Münster, Institut für Rechtsgeschichte. Welles to Koschaker letters: Five letters from Professor C. Bradford Welles to Paul Koschaker. Die Ehe von Ruth: A manuscript entitled “Die Ehe von Ruth” (unknown author).
2-D structure of the Neurospora crassa plasma membrane ATPase as determined by electron cryomicroscopy.
Creators: name: Auer, M
name: Cyrklaff, M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: Large, well-ordered 2-D crystals of the dodecylmaltoside complex of the Neurospora crassa plasma membrane H(+)-ATPase grow rapidly on the surface of a polyethylene glycol-containing mixture similar to that originally developed for growing 3-D crystals of this integral membrane transport protein. Negative stain electron microscopy of the crystals shows that many are single layers. Cryoelectron microscopy of unstained specimens indicates that the crystals have a p6 layer group with unit cell dimensions of a = b = 167 A. Image processing of selected electron micrographs has yielded a projection map at 10.3 A resolution. The repeating unit of the ATPase crystals comprises six 100 kDa ATPase monomers arranged in a symmetrical ring. The individual monomers in projection are shaped like a boot. These results provide the first indications of the molecular structure of the H(+)-ATPase molecule. They also establish the feasibility of precipitant-induced surface growth as a rapid, simple alternative to conventional methods for obtaining 2-D crystals of the integral membrane proteins useful for structure analysis.
Ivermectin: Panacea or true promise for COVID-19?
Creators: name: Heimfarth, Luana
name: Santos, Victor Santana
name: Araújo, Adriano Antunes De Souza
name: Quintans-Júnior, Lucindo José
name: Martins-Filho, Paulo Ricardo
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2020
Subjects: SARS-CoV-2
ivermectin
drug

description: EXCLI Journal; 19:Doc1517; ISSN 1611-2156
Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy.
Creators: name: Wang, Y
name: Cech, T
name: Zaug, A
name: Nakamura, T
name: Griffith, J
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: The relative orientation of helical elements in a folded RNA molecule provides key information about its three-dimensional architecture. We have developed a method that involves extending peripheral helices of an RNA, mounting for electron microscopy in the absence of protein and measuring interhelical angles. As a control, extended anticodon and acceptor stems of tRNA(Phe) were found to form a 92 +/- 20 degrees angle, consistent with the X-ray structure. Single, double and triple extensions (50-80 bp) of helical elements P2.1, P6b and P8 of the Tetrahymena group I ribozyme did not alter its catalytic activity. The measured angle between P6b and P8 is consistent with the Michel-Westhof structural model, while the P2.1-P6b and P2.1-P8 angles allow P2.1 to be positioned in the model. The angle distributions of the ribozyme are broader than those of the tRNA, which may reflect the dynamics of the RNA. Helix extension allows low-resolution electron microscopy to provide much higher resolution information about the disposition of helical elements in RNA. It should be applicable to diverse RNAs and ribonucleoprotein complexes.
Bond Option Valuation
Creators: name: Lee, David
Publisher: name: Zenodo
Year: 2023
Subjects: Bond Option Valuation

description: We present a pricing model for bond option. Assuming that the bond price at the maturity of the option is lognormal, the model adopts the Black’s analytical closed-form solution. both the underlying spot price of bond and the strike price are clean prices (quoted prices), while dirty prices are used in the price dynamic and the closed-form solution.
description: https://ia904707.us.archive.org/2/items/variable-mbs/VariableMbs.pdf
A pathway in the yeast cell division cycle linking protein kinase C (Pkc1) to activation of Cdc28 at START.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: In an effort to study further the mechanism of Cdc28 function and cell cycle commitment, we describe here a genetic approach to identify components of pathways downstream of the Cdc28 kinase at START by screening for mutations that decrease the effectiveness of signaling by Cdc28. The first locus to be characterized in detail using this approach was PKC1 which encodes a homolog of the Ca(2+)-dependent isozymes of the mammalian protein kinase C (PKC) superfamily (Levin et al., 1990). By several genetic criteria, we show a functional interaction between CDC28 and PKC1 with PKC1 apparently functioning with respect to bud emergence downstream of START. Consistent with this, activity of the MAP kinase homolog Mpk1 (a putative Pkc1 effector) is stimulated by activation of Cdc28. Furthermore, we demonstrate a cell cycle-dependent hydrolysis of phosphatidylcholine to diacylglycerol (a PKC activator) and choline phosphate at START. Diacylglycerol production is stimulated by Cdc28 in cycling cells and is closely associated with Cdc28 activation at START. These results imply that the activation of Pkc1, which is known to be necessary during bud morphogenesis, is mediated via the CDC28-dependent stimulation of PC-PLC activity in a novel cell cycle-regulated signaling pathway.
Deep scene-scale material estimation from multi-view indoor captures
Creators: name: Prakash, Siddhant
name: Rainer, Gilles
name: Bousseau, Adrien
name: Drettakis, George
Publisher: name: arXiv
Year: 2022
Subjects: subject: Graphics (cs.GR)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences
subject: I.3
subject: 68U05

description: The movie and video game industries have adopted photogrammetry as a way to create digital 3D assets from multiple photographs of a real-world scene. But photogrammetry algorithms typically output an RGB texture atlas of the scene that only serves as visual guidance for skilled artists to create material maps suitable for physically-based rendering. We present a learning-based approach that automatically produces digital assets ready for physically-based rendering, by estimating approximate material maps from multi-view captures of indoor scenes that are used with retopologized geometry. We base our approach on a material estimation Convolutional Neural Network (CNN) that we execute on each input image. We leverage the view-dependent visual cues provided by the multiple observations of the scene by gathering, for each pixel of a given image, the color of the corresponding point in other images. This image-space CNN provides us with an ensemble of predictions, which we merge in texture space as the last step of our approach. Our results demonstrate that the recovered assets can be directly used for physically-based rendering and editing of real indoor scenes from any viewpoint and novel lighting. Our method generates approximate material maps in a fraction of time compared to the closest previous solutions.
description: 17 pages
The structure and function of the replication terminator protein of Bacillus subtilis: identification of the 'winged helix' DNA-binding domain.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: The replication terminator protein (RTP) of Bacillus subtilis impedes replication fork movement in a polar mode upon binding as two interacting dimers to each of the replication termini. The mode of interaction of RTP with the terminus DNA is of considerable mechanistic significance because the DNA-protein complex not only localizes the helicase-blocking activity to the terminus, but also generates functional asymmetry from structurally symmetric protein dimers. The functional asymmetry is manifested in the polar impedance of replication fork movement. Although the crystal structure of the apoprotein has been solved, hitherto there was no direct evidence as to which parts of RTP were in contact with the replication terminus. Here we have used a variety of approaches, including saturation mutagenesis, genetic selection for DNA-binding mutants, photo cross-linking, biochemical and functional characterizations of the mutant proteins, and X-ray crystallography, to identify the regions of RTP that are either in direct contact with or are located within 11 angstroms of the replication terminus. The data show that the unstructured N-terminal arm, the alpha3 helix and the beta2 strand are involved in DNA binding. The mapping of amino acids of RTP in contact with DNA, confirms a 'winged helix' DNA-binding motif.
High-Tc Phase of PrO0.5F0.5BiS2 single crystal induced by uniaxial pressure
Creators: name: Fujioka, Masaya
name: Nagao, Masanori
name: Denholme, Saleem J.
name: Tanaka, Masashi
name: Takeya, Hiroyuki
name: Yamaguchi, Takahide
name: Takano, Yoshihiko
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We demonstrated a pressure-induced phase transition from a low-Tc phase (3.5 K) to a high-Tc phase (8.7 K) in single crystalline PrO0.5F0.5BiS2. The high-Tc phase is easily observed even at 0.7 GPa by uniaxial pressure obtained from a geometric effect of a single crystal with an extremely-thin thickness. For this phase transition, superconducting anisotropy and the coherence length along the c axis change from γ = 20 to 9.3 and from ξc = 0.56 to 0.71 nm respectively. It is suggested that a shrinkage in the c lattice constant by applied uniaxial pressure enhances the three dimensionality in the superconducting state.
description: 12 pages, 4 figures, Appl. Phys. Lett., accepted
Universitätsbibliothek, Ludwig-Maximilians-Universität, Munich
Creators: name: Giltaij, Jacob
Publisher: name: Zenodo
Year: 2018
Subjects: Helmut Coing
Karl Larenz
Franz Wieacker

description: Archival notes from Universitätsbibliothek, Ludwig-Maximilians-Universität zu München, Munich. NL Larenz Coing 18.6.1952: A letter of Helmut Coing to Karl Larenz from the Nachlass Karl Larenz. NL Larenz Wieacker 25.11.1952-8.4.1970: Letters of Franz Wieacker to Karl Larenz from the Nachlass Karl Larenz.
The Ongoing Impact of Modular Localization on Particle Theory
Creators: name: Schroer, Bert
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Modular localization is the concise conceptual formulation of causal localization in the setting of local quantum physics. Unlike QM it does not refer to individual operators but rather to ensembles of observables which share the same localization region, as a result it explains the probabilistic aspects of QFT in terms of the impure KMS nature arising from the local restriction of the pure vacuum. Whereas it played no important role in the perturbation theory of low spin particles, it becomes indispensible for interactions which involve higher spin $s\geq1$ fields, where is leads to the replacement of the operator (BRST) gauge theory setting in Krein space by a new formulation in terms of stringlocal fields in Hilbert space. The main purpose of this paper is to present new results which lead to a rethinking of important issues of the Standard Model concerning massive gauge theories and the Higgs mechanism. We place these new findings into the broader context of ongoing conceptual changes within QFT which already led to new nonperturbative constructions of models of integrable QFTs. It is also pointed out that modular localization does not support ideas coming from string theory, as extra dimensions and Kaluza-Klein dimensional reductions outside quasiclassical approximations. Apart from hologarphic projections on null-surfaces, holograhic relations between QFT in different spacetime dimensions violate the causal completeness property, this includes in particular the Maldacena conjecture. Last not least, modular localization sheds light onto unsolved problems from QFT's distant past since it reveals that the Einstein-Jordan conundrum is really an early harbinger of the Unruh effect.
description: a small text overlap with unpublished arXiv:1201.6328
Collection Mario Varvaro, Palermo
Creators: name: Beggio, Tommaso
Publisher: name: Zenodo
Year: 2018
Subjects: Salvatore Riccobono
Franz Wieacker
Fritz Schulz
Paul Koschaker
Helene Koschaker

description: Archival notes from the collection of Professor Mario Varvaro (Università degli Studi di Palermo, Dipartimento di Storia del Diritto). Koschaker to Riccobono letters 1930-1951: Nine letters written by Paul Koschaker (plus three written by his wife, Helene) to Salvatore Riccobono. Schulz to Riccobono letters 1946: Two letters written by Fritz Schulz to Salvatore Riccobono. Wieacker to Riccobono letters 1940-1951: Four letters written by Franz Wieacker to Salvatore Riccobono.
NONLINEAR METHODS FOR DEVELOPMENT OF LABEL-FREE HIGH-CONTENT SCREENING INSTRUMENTATION
Creators: name: III, Kent Alan Brasseale
Publisher: name: Purdue University Graduate School
Year: 2023
Subjects: Sensor technology (incl. chemical aspects)
Analytical spectrometry

description: Fluorescent labeling and imaging techniques have become a standard for high-content screening (HCS), wherein autonomous spectroscopic imaging leads to detailed information related to multiple biological parameters. However, the chemical labels these fluorescent methods rely on introduce significant challenges to analyzing live cells, such as perturbation to metabolic pathways, poor chemical selectivity, and limited detection channels. Nonlinear spectroscopic methods have historically been incapable of demonstrating competency in high-content screening due to some of the unique qualifications required for sample excitation and signal collection. Nonlinear optical sources of excitation, notably coherent anti-Stokes Raman scattering (CARS), is a rapidly developing field with a label-free nature capable of successfully addressing the shortcomings of fluorescence spectroscopy in many experimental environments, while also presenting unique impediments of its own. Among these are the short working distance incompatible with microplates and the requirement of transmission signal detection to achieve high sensitivity, restricting the application of CARS for HCS. Early attempts to construct the desired HCS pipeline using visible stimulated Raman scattering (SRS) were diverted due to an inability to balance detrimental photodamage with the need for increased energy input to maintain satisfactory signal generation. We developed a label-free CARS HCS platform using a pulse-picking technology and supporting imaging software to image live cells in the epi-direction with high resolution. This configuration allows the use of microplates and a surrounding incubation chamber for precision sample control and the simultaneous label-free chemical analysis of up to 64 conditions. This novel CARS-HCS platform allows automatic quantification and time-lapse monitoring of numerous conditions within a precision-controlled microenvironment.
The transition of pre-BI to pre-BII cells is dependent on the VH structure of the mu/surrogate L chain receptor.
Creators: name: Clarke, S
name: Ye, J
name: McCray, S
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: We have demonstrated previously that the majority ( > 90%) of VH12 B cells are absent from the adult peripheral repertoire, and that most that remain have the fourth position at the D-J function (designated 10/G4). We report here that most VH 12-expressing pre-B cells are lost during the transition from the pre-BI to the pre-BII cell stage in normal mice, and that pre-BII cell productive (P) rearrangements ar enriched in 10/G4 CDR3. This coincides with the initial expression of H chain and the generation of the mu/surrogate L chain (SL) receptor. In contrast, there is not enrichment for 10/G4 CDR3 in mu MT mice, and the frequency of P rearrangements is as expected from a random rearrangement mechanism, ruling out a biased rearrangement mechanism unique to VH12. We have also demonstrated that non-10/G4 mu chains can associate with SL and be expressed on the cell surface, suggesting that they are available on the cell surface for selection. Thus, transition of pre-BI to pre-BII cells is dependent on the structure of the VH domain.
Pertanyaan Survey Pemilihan Platform E-Commerce dengan Metode Weigthed Product
Creators: name: Sim, Liefran
name: Christopher, Michael
name: Dhiya, Hasna
name: Panjaitan, Juan
name: Rakhmawati, Aini
Publisher: name: Zenodo
Year: 2022
Subjects: Weigthed Product
E-Commerce

description: Publikasi ini berisi pertanyan-pertanyaan yang digunakan untuk survey dalam penelitian yang berjudul "Pemilihan Platform E-Commerce dengan Metode Weigthed Product".
description: {"references": ["Ramadhani, Hafni, \"FAKTOR PEMILIHAN E-MARKETPLACE DI INDONESIA DARI PERSPEKTIF PENJUAL (Studi Kasus: Tokopedia dan Shopee),\" Yogyakarta: Universitas Islam Indonesia, 2020.\tRamadhani, Hafni, \"FAKTOR PEMILIHAN E-MARKETPLACE DI INDONESIA DARI PERSPEKTIF PENJUAL (Studi Kasus: Tokopedia dan Shopee),\" Yogyakarta: Universitas Islam Indonesia, 2020.", "Sasmita, Dian, et al, \"ANALISIS KUALITAS LAYANAN PADA PLATFORM E-COMMERCE DI INDONESIA MENGGUNAKAN TOPIC MODELING DAN ANALISIS SENTIMEN (Studi Kasus: Tokopedia, Shopee, Bukalapak),\" e-Proceeding of Management: Vol.8, No.1, 2021"]}
Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Constitutive activation of growth factor receptor signaling pathways leads to uncontrolled growth, but why tumor cells become anchorage independent is less clear. The fact that integrins transmit signals required for cell growth suggests that constitutive activation of steps downstream from integrins mediates anchorage independence. Since the small GTPase Rho may mediate integrin signal transduction, the effects of serum and the Rho nucleotide exchange factor oncogenes dbl and lbc on cell growth and signaling pathways were examined. Our data show that these oncogenes induce anchorage-independent but serum-dependent growth and stimulation of signaling pathways. These results show, therefore, that anchorage-independent growth results from constitutive activation of integrin-dependent signaling events. They also support the view that Rho is a functionally important mediator of integrin signaling.
Azimuthally integrated HBT parameters for charged pions in nucleus-nucleus interactions versus collision energy
Creators: name: Okorokov, V. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the paper energy dependence of space-time extent of emission region obtained from Bose - Einstein correlations is studied for charged pions in various ion collisions for all experimentally available energies. There is no dramatic change of HBT parameters with increasing of collision energy per nucleon-nucleon pair, $\sqrt{s_{NN}}$, in domain of energies $\sqrt{s_{NN}} \geq 5$ GeV. Energy dependence of estimations for emission duration is almost flat for all energy domain under study within large error bars. Analytic function is suggested for smooth approximation of energy dependence of main HBT parameters. Fit curves demonstrate reasonable agreement with experimental data for most HBT parameters in energy domain $\sqrt{s_{NN}} \geq 5$ GeV. Estimations of some observables are obtained for energies of the LHC and FCC project.
description: 14 pages, 6 figures, 4 tables
High-precision $D^0 \to V^+P^-$ - more accurate than $D^0\to P^+P^-$
Creators: name: Gronau, Michael
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Recently we derived a nonlinear U-spin amplitude relation for $D^0\to P^+P^-$, $P=π, K$, predicted to hold up to fourth order U-spin breaking terms of order $10^{-3}$. Here we study a similar relation for $D^0\to V^+P^-, V =ρ, K^*(892), P = π, K$, expected to hold at an even higher accuracy of order $10^{-4}$. We confirm this prediction in spite of a large experimental error of about 20% in the amplitude of $D^0\to K^{*+}π^-$. We also comment briefly on U-spin breaking in $D^0\to P^+V^-$.
description: minor addition, to be published in Physical Review D
Spectral Design for Matrix Hamiltonians: Different Methods of Constructing of a Matrix Intertwining Operator
Creators: name: Sokolov, Andrey V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study intertwining relations for $n\times n$ matrix non-Hermitian, in general, one-dimensional Hamiltonians by $n\times n$ matrix linear differential operators with nondegenerate coefficients at $d/dx$ in the highest degree. Some methods of constructing of $n\times n$ matrix intertwining operator of the first order of general form are proposed and their interrelation is examined. As example we construct $2\times2$ matrix Hamiltonian of general form intertwined by operator of the first order with the Hamiltonian with zero matrix potential. It is shown that one can add for the final $2\times2$ matrix Hamiltonian with respect to the initial matrix Hamiltonian with the help of intertwining operator of the first order either up to two bound states for different energy values or up to two bound states described by vector-eigenfunctions for the same energy value or up to two bound states described by vector-eigenfunction and associated vector-function for the same energy value.
description: 39 pages
Domain movements of plasma membrane H+-ATPase: 3D structures of two states by electron cryo-microscopy
Creators: name: Scarborough, Gene A.
name: Henderson, Richard
name: Rhee, Kyong Hi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: H+-ATPase is a P-type ATPase that transports protons across membranes using the energy from ATP hydrolysis. This hydrolysis is coupled to a conformational change between states of the protein, in which the proton-binding site is alternately accessible to the two sides of the membrane with an altered affinity. When isolated from Neurospora crassa, H+-ATPase is a 600 kDa hexamer of identical 100 kDa polypeptides. We have obtained the three-dimensional structures of both ligand-free and Mg2+/ADP-bound states of this complex using single-particle electron cryo- microscopy. Structural comparisons, together with the difference map, indicate that there is a rearrangement of the cytoplasmic domain on Mg2+/ADP binding, which consists of a movement of mass towards the 6-fold axis causing the structure to become more compact, accompanied by a modest conformational change in the transmembrane domain.
Landesarchiv Nordrhein-Westfalen, Duisburg
Creators: name: Erkkilä, Ville
Publisher: name: Zenodo
Year: 2018
Subjects: Franz Wieacker
Carl Schmitt

description: Archival notes from Landesarchiv Nordrhein-Westfalen, Duisburg, Germany. Nachlass Carl Schmitt, RW 0265_17971-17978: Seven letters from Franz Wieacker to Carl Schmitt, 1935-1944.
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy
Creators: name: Lavi, Sara
name: Neckers, Len
name: Patterson, Cam
name: Alroy, Iris
name: Grammatikakis, Nicolas
name: Citri, Ami
name: Fry, David W.
name: Xu, Wanping
name: Rubin, Chanan
name: Yarden, Yosef
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Overexpression of ErbB-2/HER2 is associated with aggressive human malignancies, and therapeutic strategies targeting the oncoprotein are currently in different stages of clinical application. Tyrosine kinase inhibitors (TKIs) that block the nucleotide-binding site of the kinase are especially effective against tumors. Here we report an unexpected activity of TKIs: along with inhibition of tyrosine phosphorylation, they enhance ubiquitylation and accelerate endocytosis and subsequent intracellular destruction of ErbB-2 molecules. Especially potent is an irreversible TKI (CI-1033) that alkylates a cysteine specific to ErbB receptors. The degradative pathway stimulated by TKIs appears to be chaperone mediated, and is common to the heat shock protein 90 (Hsp90) antagonist geldanamycin and a stress-induced mechanism. In agreement with this conclusion, CI-1033 and geldanamycin additively inhibit tumor cell growth. Based upon a model for drug-induced degradation of ErbB-2, we propose a general strategy for selective destruction of oncoproteins by targeting their interaction with molecular chaperones.
Synapsis of DNA ends by DNA-dependent protein kinase
Creators: name: Griffith, Jack D.
name: DeFazio, Lisa G.
name: Chu, Gilbert
name: Stansel, Rachel M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The catalytic subunit of DNA-dependent protein kinase (DNA-PKCS) is required for a non-homologous end-joining pathway that repairs DNA double-strand breaks produced by ionizing radiation or V(D)J recombination; however, its role in this pathway has remained obscure. Using a neutravidin pull-down assay, we found that DNA-PKCS mediates formation of a synaptic complex containing two DNA molecules. Furthermore, kinase activity was cooperative with respect to DNA concentration, suggesting that activation of the kinase occurs only after DNA synapsis. Electron microscopy revealed complexes of two DNA ends brought together by two DNA-PKCS molecules. Our results suggest that DNA-PKCS brings DNA ends together and then undergoes activation of its kinase, presumably to regulate subsequent steps for processing and ligation of the ends.
An analysis of the intermediate field theory of $T^4$ tensor model
Creators: name: Nguyen, Viet Anh
name: Dartois, Stephane
name: Eynard, Bertrand
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we analyze the multi-matrix model arising from the intermediate field representation of the tensor model with all quartic melonic interactions. We derive the saddle point equation and the Schwinger-Dyson constraints. We then use them to describe the leading and next-to-leading eigenvalues distribution of the matrices.
description: 16 pages, 2 figures
Archives of the Society for the Protection of Science and Learning, Bodleian Library, Oxford
Creators: name: Giltaij, Jacob
Publisher: name: Zenodo
Year: 2018
Subjects: Fritz Pringsheim
Fritz Schulz

description: Archival notes from the Archives of the Society for the Protection of Science and Learning, Bodleian Library, Oxford. Schulz MS SPSL 129.1-129.2: Files from the archives of the Society for the Protection of Science and Learning (currently: CARA, Council for the Assistence of Refugee Academics):
 - MS. SPSL. folder 129.1, ordered by university, checked folder marked 'Oxford'.
 - MS. SPSL. folder 129.2, Oxford ordered by college, checked folder marked 'Balliol'. Pringsheim MS SPSL 272.1: Files from the archives of the Society for the Protection of Science and Learning (currently: CARA). Schulz MS SPSL 274.2: Files from the archives of the Society for the Protection of Science and Learning (currently: CARA). Folder contains MS. SPSL. 274.1-3, no subdivision is made within the folder, material on Schulz is assumed to be part of MS. SPSL. 274.2 alone, due to the reference in Wolfgang Ernst: “Fritz Schulz (1879-1957)”, in Jurists Uprooted (eds. Jack Beatson and Reinhard Zimmermann), Oxford: Oxford University Press, 2004, 105-203. Pringsheim MS SPSL 438.4: Files from the archives of the Society for the Protection of Science and Learning (currently: CARA), with special reference to the 'Deutsche Notgemeinschaft'. Schulz MS SPSL 441.2: Files from the archives of the Society for the Protection of Science and Learning (currently: CARA). Overlap with MS. SPSL. 129,2, folder 'Balliol'.
Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs
Creators: name: Schäcke, Heike
name: Bruckner-Tuderman, Leena
name: Zhou, Zhongjun
name: Tasanen, Kaisa
name: Lee, David C.
name: Franzke, Claus Werner
name: Fahrenholz, Falk
name: Zigrino, Paola
name: Mauch, Cornelia
name: Tryggvason, Karl
name: Sunnarborg, Susan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Collagen XVII, a type II transmembrane protein and epithelial adhesion molecule, can be proteolytically shed from the cell surface to generate a soluble collagen. Here we investigated the release of the ectodomain and identified the enzymes involved. After surface biotinylation of keratinocytes, the ectodomain was detectable in the medium within minutes and remained stable for >48 h. Shedding was enhanced by phorbol esters and inhibited by metalloprotease inhibitors, including hydroxamates and TIMP-3, but not by inhibitors of other protease classes or by TIMP-2. This profile implicated MMPs or ADAMs as candidate sheddases. MMP-2, MMP-9 and MT1-MMP were excluded, but TACE, ADAM-10 and ADAM-9 were shown to be expressed in keratinocytes and to be actively involved. Transfection with cDNAs for the three ADAMs resulted in increased shedding and, vice versa, in TACE-deficient cells shedding was significantly reduced, indicating that transmembrane collagen XVII represents a novel class of substrates for ADAMs. Functionally, release of the ectodomain of collagen XVII from the cell surface was associated with altered keratinocyte motility in vitro.
Long-term change in the cyclotron line energy in Hercules X-1
Creators: name: Staubert, R.
name: Klochkov, D.
name: Wilms, J.
name: Postnov, K.
name: Shakura, N. I.
name: Rothschild, R. E.
name: Fürst, F.
name: Harrison, F. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Aims. We investigate the long-term evolution of the Cyclotron Resonance Scattering Feature (CRSF) in the spectrum of the binary X-ray pulsar Her X-1 and present evidence of a true long-term decrease in the centroid energy Ecyc of the cyclotron line in the pulse phase averaged spectra from 1996 to 2012. Methods. Our results are based on repeated observations of Her X-1 by those X-ray observatories capable of measuring clearly beyond the cyclotron line energy of about 40 keV. Results. The historical evolution of the pulse phase averaged CRSF centroid energy Ecyc since its discovery in 1976 is characterized by an initial value around 35 keV, an abrupt jump upwards to beyond about 40 keV between 1990 and 1994, and an apparent decay thereafter. Much of this decay, however, was found to be due to an artifact, namely a correlation between Ecyc and the X-ray luminosity Lx discovered in 2007. In observations after 2006, however, we now find a statistically significant true decrease in the cyclotron line energy. At the same time, the dependence of Ecyc on X-ray luminosity is still valid with an increase of about 5% in energy for a factor of two increase in luminosity. A decrease in Ecyc by 4.2 keV over the 16 years from 1996 to 2012 can either be modeled by a linear decay, or by a slow decay until 2006 followed by a more abrupt decrease thereafter. Conclusions. We speculate that the physical reason could be connected to a geometric displacement of the cyclotron resonant scattering region in the polar field or to a true physical change in the magnetic field configuration at the polar cap by the continued accretion.
description: 11 pages, 6 figures, Astronomy & Astrophysics 2014
W-Trace: Robust and Effective Watermarking for GPS Trajectories
Creators: name: Dadwal, Rajjat
name: Funke, Thorben
name: Nüsken, Michael
name: Demidova, Elena
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: With the rise of data-driven methods for traffic forecasting, accident prediction, and profiling driving behavior, personal GPS trajectory data has become an essential asset for businesses and emerging data markets. However, as personal data, GPS trajectories require protection. Especially by data breaches, verification of GPS data ownership is a challenging problem. Watermarking facilitates data ownership verification by encoding provenance information into the data. GPS trajectory watermarking is particularly challenging due to the spatio-temporal data properties and easiness of data modification; as a result, existing methods embed only minimal provenance information and lack robustness. In this paper, we propose W-Trace - a novel GPS trajectory watermarking method based on Fourier transformation. We demonstrate the effectiveness and robustness of W-Trace on two real-world GPS trajectory datasets.
description: 4 pages, 1 figure