cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
LPCAT2 Knockdown Influences Rc, Re, and Smooth LPS-Induced TLR4 Signalling in Macrophages
Creators: name: Poloamina, Victory Ibigo
name: Wondwossen Abate
name: Gyorgy Fejer
name: Jackson, Simon K.
Publisher: name: figshare
Year: 2019
Subjects: subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Biological Techniques
subject: Cell Biology
subject: 60107 Enzymes
subject: 60405 Gene Expression (incl. Microarray and other genome-wide approaches)
subject: Immunology
subject: FOS: Clinical medicine
subject: Molecular Biology
subject: Pharmacology
subject: 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)

description: Introduction: Recognition of bacterial lipopolysaccharide (LPS) by TLR4 and its co-receptors leads to inflammation through the interaction of TLR4 signalling adaptor proteins and other proteins downstream. We have previously shown that TLR4 signalling is reduced when LPCAT2 (a phospholipid modifying enzyme) is knocked down. Smooth and Rough LPS may possess differential mechanisms of regulating TLR4 signalling, however, it is not known if the knockdown of LPCAT2 would have the same effect on TLR4 signalling induced by both smooth LPS and rough LPS.
 Materials and Methods: RAW264.7 macrophages were transfected with LPCAT2 siRNA. After 48hours, RAW264.7 were stimulated with 100ng/ml of E. Coli O111: B4, J5, and K12 LPS for 6hours to determine mRNA, and TNF-alpha protein, and 24hours to determine IL6 and IP10 protein by ELISA. Total RNA was isolated, quantified, and used for analysis of mRNA expression by real-time RT-PCR. Statistical analysis was carried out using GraphPad Prism Software.
 Results: Rough LPS (J5 and K12) induced MyD88-dependent cytokines (IL6 and TNF-alpha) about 2-fold more than smooth LPS (O111:B4), but there was no difference in the induction of MyD88-independent cytokines (IP10 and IFN-beta). Moreover, both rough and smooth LPS-induced cytokines were significantly reduced when LPCAT2 was knocked down (>70 percent ).
 Conclusions: LPCAT2 does not show a differential influence on inflammation induced by rough and smooth LPS. Moreover, LPCAT2 knockdown might be affecting the MyD88-dependent TLR4 signalling pathway more than the MyD88-independent pathway. LPCAT2 plays a role in TLR4 signalling which is important in innate immunity. Therefore, LPCAT2 can be an effective target for anti-inflammatory treatments.
Mesosathes Gaud, Atyeo and Berla
Creators: name: Barreto, Mauricio
name: Burbano, María E.
name: Proctor, Heather C.
name: Mironov, Serge V.
name: Wauthy, Georges
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Astigmata
Crypturoptidae
Mesosathes

description: Genus Mesosathes Gaud, Atyeo and Berla
 Mesosathes meniscurus Gaud, Atyeo and Berla, 1972
 Hosts and distribution. This species was described ex Crypturellus boucardi (Sclater) (Tinamiformes: Tinamidae) from Mexico, with additional material ex C. eurytropus (Pelzeln) from Guayana and Brazil and ex C. noctivagus (Wied-Neuwied) from Venezuela and Colombia (Gaud et al. 1972). This mite has never been recollected since the original description.
 Remark. According to Clements et al. (2011), C. noctivagus is restricted to Eastern Brazil, therefore it is probable that M. meniscurus was recovered from another Crypturoptes sp. in Venezuela and Colombia.
 Mesosathes schizurus Gaud, Atyeo and Berla, 1972
 Hosts and distribution. This species was described ex Crypturellus soui (Hermann) (Tinamiformes: Tinamidae) from Colombia (Dept. Norte de Santander, Petrólea; Dept. Caquetá, Puerto Venecia), with additional material from the same host from Brazil, and ex C. variegatus (Gmelin) from Venezuela and C. bartletti (Sclater and Salvin) from Peru (Gaud et al. 1972). This mite has never been recollected since the original description.
description: Published as part of Barreto, Mauricio, Burbano, María E., Proctor, Heather C., Mironov, Serge V. & Wauthy, Georges, 2012, Feather mites (Acariformes: Psoroptidia) from Colombia: Preliminary list with new records 3516, pp. 1-68 in Zootaxa 3516 on page 34
$h$-adic quantum vertex algebras associated with rational $R$-matrix in types $B$, $C$ and $D$
Creators: name: Butorac, Marijana
name: Jing, Naihuan
name: Kožić, Slaven
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Algebra (math.QA)
subject: Mathematical Physics (math-ph)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We introduce the $h$-adic quantum vertex algebras associated with the rational $R$-matrix in types $B$, $C$ and $D$, thus generalizing the Etingof--Kazhdan's construction in type $A$. Next, we construct the algebraically independent generators of the center of the $h$-adic quantum vertex algebra in type $B$ at the critical level, as well as the families of central elements in types $C$ and $D$. Finally, as an application, we obtain commutative subalgebras of the dual Yangian and the families of central elements of the appropriately completed double Yangian at the critical level, in types $B$, $C$ and $D$.
description: 27 pages
Jeans' gravitational instability and nonextensive kinetic theory
Creators: name: Lima, J. A. S.
name: Silva, R.
name: Santos, J.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The concept of Jeans gravitational instability is rediscussed in the framework of nonextensive statistics and its associated kinetic theory. A simple analytical formula generalizing the Jeans criterion is derived by assuming that the unperturbed self- gravitating collisionless gas is kinetically described by the $q$-parameterized class of power law velocity distributions. It is found that the critical values of wavelength and mass depend explicitly on the nonextensive $q$-parameter. The standard Jeans wavelength derived for a Maxwellian distribution is recovered in the limiting case $q$=1. For power-law distributions with cutoff, the instability condition is weakened with the system becoming unstable even for wavelengths of the disturbance smaller than the standard Jeans length $λ_J$.
description: 5 pages, including 3 figures. Accepted for publication in A&A
Profiling Players with Engagement Predictions
Creators: name: del Río, Ana Fernández
name: Chen, Pei Pei
name: Periáñez, África
Publisher: name: arXiv
Year: 2019
Subjects: subject: Machine Learning (cs.LG)
subject: Social and Information Networks (cs.SI)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The possibility of using player engagement predictions to profile high spending video game users is explored. In particular, individual-player survival curves in terms of days after first login, game level reached and accumulated playtime are used to classify players into different groups. Lifetime value predictions for each player---generated using a deep learning method based on long short-term memory---are also included in the analysis, and the relations between all these variables are thoroughly investigated. Our results suggest this constitutes a promising approach to user profiling.
description: Accepted for IEEE Conference on Games (CoG) 2019
Omphalosathes Gaud, Atyeo and Berla
Creators: name: Barreto, Mauricio
name: Burbano, María E.
name: Proctor, Heather C.
name: Mironov, Serge V.
name: Wauthy, Georges
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Astigmata
Crypturoptidae
Omphalosathes

description: Genus Omphalosathes Gaud, Atyeo and Berla
 Omphalosathes opistopsalidus Gaud, Atyeo and Berla, 1972
 Hosts and distribution. This species was described ex Nothocercus bonapartei (Gray) (Tinamiformes: Tinamidae) from Colombia (Dept. Magdalena, Tierra Nueva; Dept. Huila, Belén), with additional material ex Nothocercus julius (Bonaparte) from Ecuador (Gaud et al. 1972). This mite has never been recollected since the original description.
description: Published as part of Barreto, Mauricio, Burbano, María E., Proctor, Heather C., Mironov, Serge V. & Wauthy, Georges, 2012, Feather mites (Acariformes: Psoroptidia) from Colombia: Preliminary list with new records 3516, pp. 1-68 in Zootaxa 3516 on page 34
Additional file 1 of Predicting outcomes in older ED patients with influenza in real time using a big data-driven and machine learning approach to the hospital information system
Creators: name: Tian-Hoe Tan
name: Chien-Chin Hsu
name: Chia-Jung Chen
name: Shu-Lien Hsu
name: Tzu-Lan Liu
name: Hung-Jung Lin
name: Jhi-Joung Wang
name: Chung-Feng Liu
name: Huang, Chien-Cheng
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
In-situ needle fenestration technique for preserving the left subclavian artery in emergent TEVAR
Creators: name: Peixoto, João
name: Usai, Marco Virgílio
name: Austernmann, Martin
Publisher: name: Angiologia e Cirurgia Vascular
Year: 2025

description: BACKGROUND: Open aortic repair is the gold standard in the treatment of diseases involving the aortic arch, but high-risk patients are often not suitable candidates for surgical repair. Thoracic endovascular aortic repair (TEVAR) is less invasive; however, endovascular repair including the aortic arch remains a challenge. LSA revascularization is linked with reduced risk of cerebrovascular events, spinal cord ischemia, and upper limb ischemia at the cost of complications associated with carotid-subclavian bypass. In-situ fenestration (ISF) seems an effective, safe, and feasible method for the totally endovascular aortic arch repair avoiding the risks associated with bypass surgery. This technique allows for rapid, “off-the-shelf” repair of arch lesions with minimal physiologic disturbances and lower perioperative complications.

CASE REPORT: An 86-year-old man is admitted to the emergency room due to chest pain and hoarseness. There was a previous medical history of TEVAR (proximally implanted in zone 3) for penetrating thoracic aortic; 8 months prior. Computed tomography angiography revealed aneurysmal dilation of the lesser curvature of the aortic arch with a maximum diameter of 65mm. The patient was submitted to TEVAR with proximal sealing in zone 2 of the arch (Ankura™ stent-graft) and revascularization of the left subclavian artery (LSA) was achieved using an ISF by needle fenstration with the deployment of a balloon-expandable covered stent. No complications were registered. Patient initiated broad spectrum antibiotics and underwent positron emission tomography revealing several metabolically active lymph nodes suggesting underlying neoplasm.

CONCLUSION: ISF, due to its relative simplicity, is also suitable in urgent and emergent settings. It is a simple, quick technique to be added to our arsenal of endovascular procedures on the aortic arch. It may avoid the carotid-subclavian bypass as well as intentional embolization of the LSA in urgent/emergent patients. Prospective studies with long-term clinical follow-up are still lacking to fully assess the durability of these fenestrations.
description: Angiologia e Cirurgia Vascular, Vol. 20 No. 4 (2024): December
Tree Networks with Causal Structure
Creators: name: Bialas, P.
name: Burda, Z.
name: Jurkiewicz, J.
name: Krzywicki, A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Geometry of networks endowed with a causal structure is discussed using the conventional framework of equilibrium statistical mechanics. The popular growing network models appear as particular causal models. We focus on a class of tree graphs, an analytically solvable case. General formulae are derived, describing the degree distribution, the ancestor-descendant correlation and the probability a randomly chosen node lives at a given geodesic distance from the root. It is shown that the Hausdorff dimension $d_H$ of the causal networks is generically infinite, in contrast to the maximally random trees, where it is generically finite.
description: 9 pages, 2-column revtex format, 1 eps figure, misprints corrected
Additional file 5 of DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
Creators: name: Vehmeijer, Florianne O. L.
name: Küpers, Leanne K.
name: Sharp, Gemma C.
name: Salas, Lucas A.
name: Lent, Samantha
name: Jima, Dereje D.
name: Tindula, Gwen
name: Reese, Sarah
name: Qi, Cancan
name: Gruzieva, Olena
name: Page, Christian
name: Rezwan, Faisal I.
name: Melton, Philip E.
name: Nohr, Ellen
name: Escaramís, Geòrgia
name: Rzehak, Peter
name: Heiskala, Anni
name: Gong, Tong
name: Tuominen, Samuli T.
name: Gao, Lu
name: Ross, Jason P.
name: Starling, Anne P.
name: Holloway, John W.
name: Yousefi, Paul
name: Aasvang, Gunn Marit
name: Beilin, Lawrence J.
name: Bergström, Anna
name: Binder, Elisabeth
name: Chatzi, Leda
name: Corpeleijn, Eva
name: Czamara, Darina
name: Eskenazi, Brenda
name: Ewart, Susan
name: Ferre, Natalia
name: Grote, Veit
name: Gruszfeld, Dariusz
name: Håberg, Siri E.
name: Hoyo, Cathrine
name: Huen, Karen
name: Karlsson, Robert
name: Kull, Inger
name: Langhendries, Jean-Paul
name: Lepeule, Johanna
name: Magnus, Maria C.
name: Maguire, Rachel L.
name: Molloy, Peter L.
name: Monnereau, Claire
name: Mori, Trevor A.
name: Oken, Emily
name: Räikkönen, Katri
name: Rifas-Shiman, Sheryl
name: Ruiz-Arenas, Carlos
name: Sebert, Sylvain
name: Ullemar, Vilhelmina
name: Verduci, Elvira
name: Vonk, Judith M.
name: Xu, Cheng-jian
name: Yang, Ivana V.
name: Zhang, Hongmei
name: Zhang, Weiming
name: Karmaus, Wilfried
name: Dabelea, Dana
name: Muhlhausler, Beverly S.
name: Breton, Carrie V.
name: Lahti, Jari
name: Almqvist, Catarina
name: Jarvelin, Marjo-Riitta
name: Koletzko, Berthold
name: Vrijheid, Martine
name: Sørensen, Thorkild I. A.
name: Huang, Rae-Chi
name: Arshad, Syed Hasan
name: Nystad, Wenche
name: Melén, Erik
name: Koppelman, Gerard H.
name: London, Stephanie J.
name: Holland, Nina
name: Bustamante, Mariona
name: Murphy, Susan K.
name: Hivert, Marie-France
name: Baccarelli, Andrea
name: Relton, Caroline L.
name: Snieder, Harold
name: Jaddoe, Vincent W. V.
name: Felix, Janine F.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 5: Supplementary Information. Figures S1 – 6.
Envesting in an Agricultural Legacy: Impact of a Targeted Young and Beginning Farmer Loan Program in Arkansas
Creators: name: Goeringer, L. Paul
name: Goodwin, Harold L.
name: Dixon, Bruce L.
name: Popp, Michael P.
name: Goeringer, L. Paul
name: Goodwin, Harold L.
name: Dixon, Bruce L.
name: Popp, Michael P.
Publisher: name: Unknown
Year: 2012
Subjects: Agribusiness
Agricultural Finance
Farm Management
Production Economics

description: America’s agricultural producers continue to age. According to the U.S. Census of Agriculture, the average age of farm operators increased from 55.3 in 2002 to 57.1 in 2007. During the same period, the Census shows a thirty percent decrease in the number of farmers under the age of 25. Young and beginning producers (YBPs) entering agriculture can be faced with high startup costs and the lack of land to own or rent. To address this potential shortage of future farmers, we propose a program for the Farm Credit System to assist YBPs by offering Farm Service Agency guaranteed loans. In this program YBPs are given concessionary interest rates in consideration for adopting conservation and recommended “best” practices. To gauge the impact of the loan program, crop budgets were developed for corn, cotton, rice, soybeans, and wheat prior to participation in the loan program and then budgets were developed to determine the impact on a YBP’s profitability on these five crops from the adoption of no-till, a crop rotation, or a no-till crop rotation. Results found that a YBP’s profitability per acre can be improved by participating in the loan program and the adopting either no-till, a crop rotation, or a no-till crop rotation.
The use of through vial impedance spectroscopy (TVIS) for determination of ice nucleation, solidification end point, and mannitol crystallization during freezing and re-heating. Poster presentation at the APS PharmSci Conference 11-13th September 2019 Greenwich, UK
Creators: name: Ogugua, Longinus
name: Smith, Geoff
name: Orun, Ahmet
Publisher: name: De Montfort University
Year: 2019
Subjects: subject: 111504 Pharmaceutical Sciences
subject: FOS: Clinical medicine

description: This is a study of the freezing/reheating behavior of aqueous solutions of mannitol with respect to lyophilization process development given the prevalent use of the excipient. Here, through-vial impedance spectroscopy (TVIS) was used to study the thermophysical kinetics of an aqueous solution of 5%w/v mannitol during a freezing and re-heating phase of a freeze-drying cycle. Temperature calibration of the TVIS parameter FPEAK enabled the determination of the ice nucleation temperature Tn at −13 oC while the ice solidification end point was observed based on the time profile of C' (0.2MHz), i.e. the real part capacitance at 0.2 MHz. A time difference of 20 min between the onset and end point then defines the ice solidification time ti. A later step in C' (0.2MHz) indicated that mannitol crystallized at -32 oC and 20 minutes from end of ice solidification. Upon reheating at 0.2 oC/min, a large increase in C' (0.2MHz) was seen at −32 oC indicating the onset of melting of mannitol crystals which then lasted 20 min.
Design of substrate supply contracts for biogas plants
Creators: name: Reise, Christian
name: Liebe, Ulf
name: Musshoff, Oliver
name: Reise, Christian
name: Liebe, Ulf
name: Musshoff, Oliver
Publisher: name: Unknown
Year: 2012
Subjects: subject: Resource /Energy Economics and Policy
subject: Renewable energy
subject: bioenergy
subject: substrate supply contract
subject: contract design
subject: (labeled) choice experiment

description: For a sustainable development of energy production in biogas plants, the continuous supply with substrates is essential. To the authors’ knowledge, there have not been carried out any quantitative investigations of farmers’ choices with regard to supply contracts for biogas plants. Thus, it has been only possible to a limited extent to make predictions for a targeted design of supply contracts. We therefore investigated different factors, which might be relevant for the conclusion of substrate supply contracts, by conducting a survey with 178 German farmers. The survey included a choice experiment, in which participants were confronted with different contract attributes (features). These attributes were varied systematically and thus revealed the influence of each individual feature on the probability of contract conclusion. It becomes clear that the farmers interviewed prefer to conclude contracts with other farmers or with a bioenergy village to non-agricultural investors. The probability of contract conclusion decreases with an increasing lifetime of the contract. However, a contract with a higher sales price is more attractive for the farmers. The investigation of the characteristics of respondents shows that the amount of the premium for one additional year of contractual lifetime depends on the individual valuation of the entrepreneurial freedom of the respective farm manager. It cannot be established that risk-averse farmers tend to prefer contracts with fixed prices over contracts with price adjustment clauses. In addition, there are no great differences in the choice behaviour of farmers who have signed a substrate supply contract and farmers without this experience. Regarding the expansion of renewable energies, these findings are meaningful for a target-aimed design of supply contracts.
Early type stars at high galactic latitudes II. Four evolved B-type stars of unusual chemical composition
Creators: name: Ramspeck, M.
name: Heber, U.
name: Edelmann, H.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the result of differential spectral analyses of a further four apparently normal B-type stars. Abundance anomalies (e.g. He, C, N enrichment), slow rotation and/or high gravities suggest that the programme stars are evolved low-mass B-type stars. In order to trace their evolutionary status several scenarios are discussed. Post-AGB evolution can be ruled out. PG 0229+064 and PG 1400+389 could be horizontal branch (HB) stars, while HD 76431 and SB 939 have already evolved away from the extreme HB (EHB). The low helium abundance of HD 76431 is consistent with post-EHB evolution. The enrichment in helium, carbon and nitrogen of the remaining stars can be explained either by deep mixing of nuclearly processed material to the surface or by diffusion processes modified by magnetic fields and/or stellar winds. A kinematic study of their galactic orbits indicates that the stars belong to an old disk population.
description: 10 pages, 5 eps-files, accepted for publication in Astronomy and Astrophysics
Growing networks with local rules: preferential attachment, clustering hierarchy and degree correlations
Creators: name: Vazquez, Alexei
Publisher: name: arXiv
Year: 2002
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The linear preferential attachment hypothesis has been shown to be quite successful to explain the existence of networks with power-law degree distributions. It is then quite important to determine if this mechanism is the consequence of a general principle based on local rules. In this work it is claimed that an effective linear preferential attachment is the natural outcome of growing network models based on local rules. It is also shown that the local models offer an explanation to other properties like the clustering hierarchy and degree correlations recently observed in complex networks. These conclusions are based on both analytical and numerical results of different local rules, including some models already proposed in the literature.
description: 17 pages, 14 figures (to appear in Phys. Rev E)
Additional file 1 of Testing telediagnostic obstetric ultrasound in Peru: a new horizon in expanding access to prenatal ultrasound
Creators: name: Toscano, Marika
name: Marini, Thomas J.
name: Drennan, Kathryn
name: Baran, Timothy M.
name: Kan, Jonah
name: Garra, Brian
name: Dozier, Ann M.
name: Ortega, Rafael L.
name: Quinn, Rosemary A.
name: Zhao, Yu T.
name: Egoavil, Miguel S.
name: Tamayo, Lorena
name: Carlotto, Claudia
name: Castaneda, Benjamin
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 1. Obstetric Training Video.
Tinamolichus Gaud, Atyeo and Berla
Creators: name: Barreto, Mauricio
name: Burbano, María E.
name: Proctor, Heather C.
name: Mironov, Serge V.
name: Wauthy, Georges
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Astigmata
Crypturoptidae
Tinamolichus

description: Genus * Tinamolichus Gaud, Atyeo and Berla
 Tinamolichus pachycaulus Gaud, Atyeo and Berla, 1972
 Material examined. Ex Tinamus major (Gmelin) (Tinamiformes: Tinamidae): 5 males and 2 females, Dept. Valle del Cauca: Buenaventura, 21 October 1973, coll. J.I. Borrero & G. Cataño, UV No. 4027.
 Hosts and distribution. This species was described ex Tinamus m. castaineiceps Salvadori from Panama (Darien), with additional material ex T. m. saturatus Griscom from Panama, and ex T. guttatus Pelzeln from Brazil, Ecuador and Venezuela (Gaud et al. 1972).
description: Published as part of Barreto, Mauricio, Burbano, María E., Proctor, Heather C., Mironov, Serge V. & Wauthy, Georges, 2012, Feather mites (Acariformes: Psoroptidia) from Colombia: Preliminary list with new records 3516, pp. 1-68 in Zootaxa 3516 on page 34
Automatic Segmentation of Vestibular Schwannoma from T2-Weighted MRI by Deep Spatial Attention with Hardness-Weighted Loss
Creators: name: Wang, Guotai
name: Shapey, Jonathan
name: Li, Wenqi
name: Dorent, Reuben
name: Demitriadis, Alex
name: Bisdas, Sotirios
name: Paddick, Ian
name: Bradford, Robert
name: Ourselin, Sebastien
name: Vercauteren, Tom
Publisher: name: arXiv
Year: 2019
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Automatic segmentation of vestibular schwannoma (VS) tumors from magnetic resonance imaging (MRI) would facilitate efficient and accurate volume measurement to guide patient management and improve clinical workflow. The accuracy and robustness is challenged by low contrast, small target region and low through-plane resolution. We introduce a 2.5D convolutional neural network (CNN) able to exploit the different in-plane and through-plane resolutions encountered in standard of care imaging protocols. We use an attention module to enable the CNN to focus on the small target and propose a supervision on the learning of attention maps for more accurate segmentation. Additionally, we propose a hardness-weighted Dice loss function that gives higher weights to harder voxels to boost the training of CNNs. Experiments with ablation studies on the VS tumor segmentation task show that: 1) the proposed 2.5D CNN outperforms its 2D and 3D counterparts, 2) our supervised attention mechanism outperforms unsupervised attention, 3) the voxel-level hardness-weighted Dice loss can improve the performance of CNNs. Our method achieved an average Dice score and ASSD of 0.87 and 0.43~mm respectively. This will facilitate patient management decisions in clinical practice.
description: 9 pages, 4 figures, submitted to MICCAI
Lambda<0 Quantum Gravity in 2+1 Dimensions I: Quantum States and Stringy S-Matrix
Creators: name: Krasnov, Kirill
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider the theory of pure gravity in 2+1 dimensions, with negative cosmological constant. The theory contains simple matter in the form of point particles; the later are classically described as lines of conical singularities. We propose a formalism in which quantum amplitudes for process involving black holes and point particles are obtained as Liouville field theory (LFT) correlation functions on Riemann surfaces X. Point particles are described by LFT vertex operators, black holes (asymptotic regions) are in correspondence with boundaries of X. We analyze two examples: the amplitude for emission of a particle by the BTZ black hole, and the amplitude of black hole creation by two point particles. We then define an inner product between quantum states. The value of this inner product can be interpreted as the amplitude for one set of point particles to go into another set producing black holes. The full particle S-matrix is then given by the sum of all such amplitudes. This S-matrix is that of a non-critical string theory, with the world-sheet CFT being essentially the Liouville theory. Lambda<0 quantum gravity in 2+1 dimensions is thus a string theory.
description: v1: 22+1 pages, figures, v2: 25+1 pages, remarks on entropy and unitarity added
Actinide-rich and Actinide-poor $r$-Process Enhanced Metal-Poor Stars do not Require Separate $r$-Process Progenitors
Creators: name: Holmbeck, Erika M.
name: Frebel, Anna
name: McLaughlin, G. C.
name: Mumpower, Matthew R.
name: Sprouse, Trevor M.
name: Surman, Rebecca
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The astrophysical production site of the heaviest elements in the universe remains a mystery. Incorporating heavy element signatures of metal-poor, $r$-process enhanced stars into theoretical studies of $r$-process production can offer crucial constraints on the origin of heavy elements. In this study, we introduce and apply the "Actinide-Dilution with Matching" model to a variety of stellar groups ranging from actinide-deficient to actinide-enhanced to empirically characterize $r$-process ejecta mass as a function of electron fraction. We find that actinide-boost stars do not indicate the need for a unique and separate $r$-process progenitor. Rather, small variations of neutron richness within the same type of $r$-process event can account for all observed levels of actinide enhancements. The very low-$Y_e$, fission-cycling ejecta of an $r$-process event need only constitute 10-30% of the total ejecta mass to accommodate most actinide abundances of metal-poor stars. We find that our empirical $Y_e$ distributions of ejecta are similar to those inferred from studies of GW170817 mass ejecta ratios, which is consistent with neutron-star mergers being a source of the heavy elements in metal-poor, $r$-process enhanced stars.
description: 14 pages, 11 figures, Submitted to ApJ
Enoclerus minas Opitz 2020, new species
Creators: name: Opitz, Weston
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cleridae
Enoclerus
Enoclerus minas

description: Enoclerus minas Opitz, new species
Figures 1, 4.
 Type material. Holotype. ♂. Type locality: Brazil, Minas Geraes (MNHN). Paratypes: 28. Colombia: Departamento de Caldas; Manizales, collection date not noted, A. M. Patino (WOPC, 2; MNHN, 1). Brazil: Estado do Goías; Rio Verde,?-?- 1908, G. A. Baer (WOPC, 5; MNHN, 4); Jatahy, unknown- 1902, H. Donckier (WOPC, 1; MNHN, 1);?- IX-1897 (WOPC, 2); Goias (MNHN, 6); Trinidae, collection date not noted, Ch. Pujol (MNHN, 3); Estado do Amazonas; Santo Paulo de’Oliveça, collection date not noted, Hahnel (MNHN, 1); Estado do Bahia; Diamantina, collection date not noted, R. P. Torgue (MNHN,1); Rio Grande do Sul; Porto Alegre, collection date not noted, collector not noted (MNHN, 1).
 Diagnosis. Aedeagus comprised of two subparallel phallic plates, plates narrow near apex; antennae and legs testaceous; cranium black; elytra mostly black, each elytron with three yellow maculae, anterior two maculae nearly contiguous; elytral apex slightly setose.
 Description. Size: Length 6.0 mm; width 1.0 mm. Form: As in Figure 4. Head: Capitulum slightly acuminate; (EW/FW 20/53). Thorax: Elytral disc slightly roughened (PL/PW 80/80); (EL/EW 220/50). Abdomen: Aedeagus (Fig. 1).
 Variation. Length 6.0–8.0 mm; width 1.0–1.1 mm.
 Etymology. The trivial name, minas, constitutes a noun in apposition and refers to the type locality.
 Remarks. Enoclerus minas is from the Cordillera Oriental Complex and the Brazilian Highlands (Opitz 2005). The red legs and elytral color pattern, along with a subparallel aedeagus that is narrowed apically distinguish this species from all others in this region.
description: Published as part of Opitz, Weston, 2020, Three new species of South American checkered beetles (Coleoptera: Cleridae: Clerinae), pp. 1-5 in Insecta Mundi 2020 (832) on page 2, DOI: 10.5281/zenodo.5353866
INVESTIGATING THE INFLUENCE OF DOXORUBICIN AND PACLITAXEL ON THE ACTIVITY AND EXPRESSION OF CYTOCHROME P450s IN MOUSE LIVER MICROSOME USING VIVID ASSAYS
Creators: name: Poloamina, Victory Ibigo
Publisher: name: figshare
Year: 2019
Subjects: subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Biological Techniques
subject: Cell Biology
subject: 60107 Enzymes
subject: 60405 Gene Expression (incl. Microarray and other genome-wide approaches)
subject: Immunology
subject: FOS: Clinical medicine
subject: Molecular Biology
subject: Pharmacology
subject: 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)

description: Proteins are primary effectors of drug action, hence it is essential to study how drugs can affect protein expression, and activity. In cancer research, it is common to study the effects of anticancer drugs on proteins. Pharmacoproteomics plays an important role in determining the effects of anti-cancer drugs on protein expression. More so, the effect of drugs on protein activity can be studied using enzymatic assays, such as vivid assay. The influence of doxorubicin, doxorubicin-solvent, paclitaxel, and paclitaxel-solvent on the activity of cytochrome p450 enzymes present in mouse liver microsomes was analysed. The differences in gender was also observed. Given that vivid assays are designed for human models, the ability to use mouse models for vivid assays was also determined. Vivid assay revealed that female mice had generally higher activity than male mice, after analysis with 20mg/ml (male) and 100mg/ml (female) mouse liver microsomal fraction. The exact alteration in cytochrome p450 activity cannot be determined due to the lack of specificity of the substrates and the presence of other proteins in the samples. However, the protein activity observed could be partly due to the presence of CYP450 enzymes in the samples. There was a significant difference between treated and untreated female samples (p ≥ 0.05), however, treated and untreated male samples showed no significant difference (p ≤ 0.05). This experiment showed that it is possible to use mouse models for vivid assays although some improvements may be necessary.
A Study of the Effect of Resolving Negation and Sentiment Analysis in Recognizing Text Entailment for Arabic
Creators: name: AL-Khawaldeh, Fatima T.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Recognizing the entailment relation showed that its influence to extract the semantic inferences in wide-ranging natural language processing domains (text summarization, question answering, etc.) and enhanced the results of their output. For Arabic language, few attempts concerns with Arabic entailment problem. This paper aims to increase the entailment accuracy for Arabic texts by resolving negation of the text-hypothesis pair and determining the polarity of the text-hypothesis pair whether it is Positive, Negative or Neutral. It is noticed that the absence of negation detection feature gives inaccurate results when detecting the entailment relation since the negation revers the truth. The negation words are considered stop words and removed from the text-hypothesis pair which may lead wrong entailment decision. Another case not solved previously, it is impossible that the positive text entails negative text and vice versa. In this paper, in order to classify the text-hypothesis pair polarity, a sentiment analysis tool is used. We show that analyzing the polarity of the text-hypothesis pair increases the entailment accuracy. to evaluate our approach we used a dataset for Arabic textual entailment (ArbTEDS) consisted of 618 text-hypothesis pairs and showed that the Arabic entailment accuracy is increased by resolving negation for entailment relation and analyzing the polarity of the text-hypothesis pair.
description: 5 pages
Integral Motives and Special Values of Zeta Functions
Creators: name: Milne, James S.
name: Ramachandran, Niranjan
Publisher: name: arXiv
Year: 2002
Subjects: subject: Number Theory (math.NT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 11G99, 14G15, 14F42

description: For each field k, we define an abelian category of rationally decomposed mixed motives with integer coefficients. When k is finite, we show that the category is Tannakian, and we prove formulas relating the behaviour of zeta functions near integers to certain Ext groups. This is the submitted version, with minor corrections and additions from the first version.
title: Wpływ nauczania w formie zdalnej w pandemii COVID-19 na motywację do nauki studentów uczelni wyższych w kontekście teorii A. Maslowa
Creators: name: Grzelczak, Agnieszka Urszula
name: Smektała, Natalia
name: Sobczyk, Paulina
Publisher: name: Poznań University of Technology
publisherIdentifier: https://ror.org/00p7p3302
publisherIdentifierScheme: ROR
Year: 2023

description: Zeszyty Naukowe Politechniki Poznańskiej. Organizacja i Zarządzanie, 87, 83-102
New composite supernova remnant toward HESS J1844-030?
Creators: name: Petriella, Alberto
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: AIMS: HESS J1844-030 is a newly confirmed TeV source in the direction of the X-ray pulsar wind nebula (PWN) candidate G29.4+0.1 and the complex radio source G29.37+0.1, which is likely formed by the superposition of a background radio galaxy and a Galactic supernova remnant (SNR). We investigate the possible connection between the SNR, the PWN G29.4+0.1, and HESS J1844-030 to shed light on the astrophysical origin of the TeV emission. METHODS: We performed an imaging and spectral study of the X-ray emission from the PWN G29.4+0.1 using archival observations obtained with the Chandra and XMM-Newton telescopes. Public radio continuum and HI data were used to derive distance constraints for the SNR that is linked to G29.37+0.1 and to investigate the interstellar medium where it is expanding. We applied a simple model of the evolution of a PWN inside an SNR to analyze the association between G29.4+0.1 and the radio emission from G29.37+0.1. We compared the spectral properties of the system with the population of TeV PWNe to investigate if HESS J1844-030 is the very high energy counterpart of the X-ray PWN G29.4+0.1. RESULTS: We conclude that G29.4+0.1 is a PWN and that a point source embedded on it is the powering pulsar. The HI data revealed that the SNR linked to G29.37+0.1 is a Galactic source at 6.5 kpc and expanding in a nonuniform medium. From the analysis of the pulsar motion and the pressure balance at the boundary of X-ray emission, we conclude that G29.4+0.1 could be a PWN that is located inside its host remnant, forming a new composite SNR. Based on the magnetic field of the PWN obtained from the X-ray luminosity, we found that the population of electrons producing synchrotron radiation in the keV band can also produce IC photons in the TeV band. This suggests that HESS J1844-030 could be the very high energy counterpart of G29.4+0.1.
description: Accepted for publication in A&A. The quality of some of the images has been degraded. Abstract length has been reduced
Summary of interviews with NFDI consortia for determining the need for an NFDI base service for Knowledge Graph Infrastructure
Creators: name: Förstner, Konrad
name: Sauerwein, Till
Publisher: name: Zenodo
Year: 2024

description: Summary of interviews with NFDI consortia for determining the need for an NFDI base service for Knowledge Graph Infrastructure. The intervies were conducted with 26 NFDI consortia between November 2023 and February 2024.
Additional file 1 of Maternal nutrition and its intergenerational links to non-communicable disease metabolic risk factors: a systematic review and narrative synthesis
Creators: name: Wilkins, Elizabeth
name: Kremlin Wickramasinghe
name: Pullar, Jessie
name: Demaio, Alessandro R.
name: Roberts, Nia
name: Karla-Maria Perez-Blanco
name: Noonan, Katharine
name: Townsend, Nick
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Cell Biology
Pharmacology
Biotechnology

description: Additional file 1. PRISMA checklist.
Additional file 2 of Maternal nutrition and its intergenerational links to non-communicable disease metabolic risk factors: a systematic review and narrative synthesis
Creators: name: Wilkins, Elizabeth
name: Kremlin Wickramasinghe
name: Pullar, Jessie
name: Demaio, Alessandro R.
name: Roberts, Nia
name: Karla-Maria Perez-Blanco
name: Noonan, Katharine
name: Townsend, Nick
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Cell Biology
Pharmacology
Biotechnology

description: Additional file 2. Search terms.
ESSENCE-IPD: Assessments and scoring for preterm infants
Creators: name: Luling Lin
Publisher: name: figshare
Year: 2019
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences

description: Evaluation of Sex-Specific Effects of Nutrition in Children born Early: An Individual Participant Data Meta-analysis (ESSENCE-IPD)

The aim of the ESSENCE-IPD is to assemble and analyse all the available evidence by undertaking an individual participant data (IPD) meta-analysis. We hope to determine the benefits and risks of different nutritional supplements for girls and boys born small.
Impact of type 2 diabetes on postoperative outcomes after endovascular aortic aneurysm repair – a cohort study
Creators: name: Duarte, António
name: Gonçalves, Hugo Fabian
name: Gouveia E Melo, Ryan
name: Amorim, Pedro
name: Fernandes E Fernandes, Ruy
name: Mendes Pedro, Luís
Publisher: name: Angiologia e Cirurgia Vascular
Year: 2025

description: INTRODUCTION: Although the incidence of abdominal aortic aneurysms (AAA) has declined over the last two decades, this condition has high mortality rates when symptomatic or ruptured. Paradoxically, diabetes seems to slow AAA progression or rupture. However, there is little and contradictory data regarding the postoperative setting. This study aims to evaluate the clinical impact of diabetes after standard EVAR.

MATERIALS AND METHODS: We performed a retrospective cohort study with consecutively enrolled patients who underwent EVAR at a tertiary center between January 2013 and April 2022. Patients were categorized according to the presence of type 2 diabetes. The primary outcome was the incidence rate of aortic events (aortic reinterventions, rupture, and mortality). Secondary outcomes comprised overall mortality, endoleak rate and sac diameter variation during follow-up. Pearson’s Chi-squared test was performed for descriptive analysis. Survival and multivariable analyses were performed through Cox proportional regression models.

RESULTS: A total of 381 patients comprised this cohort, with 82 (21%, 95% CI 17.5-26) identified as diabetic. The average follow-up duration was 27±24 months. Diabetic patients showed a higher prevalence of dyslipidemia (91.4% vs. 74.3%, p<0.001) and hypertension (95.1% vs. 85.1%, p =0.016). Most patients were treated with oral antidiabetics (86.6%), primarily metformin (62.1%). Additionally, 9% of diabetics received insulin therapy. A non-significant trend indicated that diabetic patients experienced a higher incidence of aortic events, particularly after 12 months (adjusted hazard ratio [aHR]: 1.39, 95% confidence interval [CI] 0.71-2.73). Notably, mortality rates were significantly higher among diabetic patients (aHR: 1.86; p=0.02). However, diabetes did not affect sac shrinkage or endoleak rate.

CONCLUSION: While diabetes seems to slow AAA progression, this condition appears to have a negative influence after EVAR, with a higher rate of aortic events and overall mortality. Further studies should explore the interplay between these conditions.
description: Angiologia e Cirurgia Vascular, Vol. 20 No. 4 (2024): December
Enoclerus salta Opitz 2020, new species
Creators: name: Opitz, Weston
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cleridae
Enoclerus
Enoclerus salta

description: Enoclerus salta Opitz, new species
Figures 2, 5.
 Type material. Holotype. ♂. Type locality: Argentina, Salta, La Liña, 23-2-1992 (RGCM). Paratypes: 9. Argentina: Provincia de Salta; 3 km S Cnel Moldes, 23-I-1989, C. L. Bellamy (WFBM, 1); 4 km S Coronel Moldes, I-23-1989, 1,150, collector not noted (UCDC, 1); Provincia Santiago del Estero; Ojo de Agua, 4-III-1992, collector not noted (RGCM, 1); Provincia de Salta; Alemania, 23-II-1992, collector not noted (RGCM, 1); 5 km N Cnel Moldes, 23-I-1989, C. L. Bellamy (WOPC, 1); Sumalao,?- I-1992, collector not noted (WOPC, 1); Provincia de Córdaba;?- II-1939, M. J. Viana (WOPC, 2); Provincia de Tucumán; Tapia, 3-IV- 1903, 600 m, G. A. Baer (MNHN, 1).
 Diagnosis. Aedeagus comprised of two parallel sided phallic plates, plates obtusely rounted at apex; mouthparts, antennae, and legs testaceous; cranuim black; pronotum mostly testaceous, arch infustated and partialy setose; elytra tricolored, basal 1/3 setaceous, apical 2/3 mostly black, each elytral with two small punctiform maculae at base, and two crescentic maculae on apical third; elytral apex highly setose.
 Description. Size: Length 8.0 mm; width 1.3 mm. Form: As in Figure 5. Head: Capitulum slightly acuminate; (EW/FW 23/60). Thorax: Elytral disc slightly roughened (PL/PW 120/120); (EL/EW 270/80). Abdomen: Aedeagus (Fig. 2).
 Variation. Length 6.0 – 8.0 mm; width 1.0 – 1.3 mm. The forebody may be entirely testaceous.
 Etymology. The trivial name, salta, constitutes a noun in apposition and refers to the type locality.
 Remarks. Enoclerus salta is from the Argentinian Highlands (Opitz 2005). The crescentic elytral maculae and parallel sided aedeagus distinguish this species from all others from the region.
description: Published as part of Opitz, Weston, 2020, Three new species of South American checkered beetles (Coleoptera: Cleridae: Clerinae), pp. 1-5 in Insecta Mundi 2020 (832) on pages 2-4, DOI: 10.5281/zenodo.5353866
Image and Non-Image Parameters of Atmospheric Cherenkov Events: a comparative study of their gamma-ray/hadron classification potential in UHE regime
Creators: name: Razdan, A.
name: Haungs, A.
name: Rebel, H.
name: Bhat, C. L.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this exploratory simulation study, we compare the event-progenitor classification potential of a variety of measurable parameters of atmospheric Cherenkov pulses which are produced by ultra-high energy (UHE) gamma-ray and hadron progenitors and are likely to be recorded by the TACTIC array of atmospheric Cherenkov telescopes. The parameters derived from Cherenkov images include Hillas, fractal and wavelet moments, while those obtained from non-image Cherenkov data consist of pulse profile rise-time and base width and the relative ultraviolet to visible light content of the Cherenkov event. It is shown by a neural-net approach that these parameters, when used in suitable combinations, can bring about a proper segregation of the two event types, even with modest sized data samples of progenitor particles.
description: 18 pages, accepted at Astroparticle Physics
Conceptual design of the TRIUMF thermal neutron facility
Creators: name: Thorson, I. M.
name: Arrott, A. S.
Publisher: name: TRIUMF
Year: 2016

description: The report describes the conceptual design of the proposed thermal neutron facility (TNF) based on the neutron source produced by dumping the residual beam from the main TRIUMF proton beam line into a high atomic weight target. The maximum useful thermal neutron flux in a water-reflected, 120 cm diam heavywater- graphite moderator assembly surrounding a 15 cm diam Pb-Bi target is ~0.9 x 10¹³ cmｰ² secｰ¹ at 50 kW residual beam power; this figure is higher by a factor of ~2.5 for a natural uranium target. The neutron irradiation and beam tube facilities are described as well as facilities for carrying out proton beam irradiations. Heat dissipation and residual activity problems are discussed and a preliminary cost estimate is given. The total estimated cost, without any contingency allowance, is $434,000, of which 60% is for shielding.