cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 10 of Reducing catheter-associated urinary tract infections: a systematic review of barriers and facilitators and strategic behavioural analysis of interventions
Creators: name: Atkins, Lou
name: Sallis, Anna
name: Chadborn, Tim
name: Shaw, Karen
name: Schneider, Annegret
name: Hopkins, Susan
name: Bunten, Amanda
name: Michie, Susan
name: Lorencatto, Fabiana
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 10. All reported barriers and facilitators within each TDF domain** identified across all care settings (primary, community, secondary and tertiary care, and care homes), nested according to COM-B
Physical properties of the solar magnetic photosphere under the MISMA hypothesis III: sunspot at disk center
Creators: name: Almeida, J. Sanchez
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Small-scale fluctuations of magnetic field and velocity may be responsible for the Stokes asymmetries observed in all photospheric magnetic structures (the MISMA hypothesis). We support the hypothesis showing that atmospheres with optically-thin micro-structure reproduce the polarization of FeI 6301 A and FeI 6302 A observed in a sunspot. Ten thousand spectra were fitted by model MISMAs with two magnetic components interleaved along the line-of-sight. Combining all the fits, we set up a semi-empirical model sunspot characterized by two components with very different magnetic field inclination. The major component, which contains most of the mass, is more vertical than the minor component. The field lines of the minor component are inclined below the horizontal plane throughout the penumbra. Magnetic field lines and mass flows are parallel, consequently, both upflows and downflows are present everywhere on the penumbra. Major and minor components have very different velocities (several hundred m/s for the major component versus 10 km/s for the minor component), but the mass transported per unit time is similar. The similarity between the vertical mass flow and the magnetic flux of the two components suggests that field lines emerging as major component may return to the photosphere as minor component. If so, the observed magnetic field strength difference between components leads to a siphon flow whose magnitude and direction agree with the inferred Evershed flow. Several tests support the internal consistency of the retrieved model sunspot. The magnetic field vector {B} does not violate the {nabla {B}=0} condition. The model sunspot reproduces the net circular polarization of the observed lines, plus the abnormal behavior of FeI 15648 A.
description: To appear in ApJ. 20 pages and 27 figures
How Many Components? Quantifying the Complexity of the Metallicity Distribution in the Milky Way Bulge with APOGEE
Creators: name: Rojas-Arriagada, A.
name: Zasowski, G.
name: Schultheis, M.
name: Zoccali, M.
name: Hasselquist, S.
name: Chiappini, C.
name: Cohen, R. E.
name: Cunha, K.
name: Fernández-Trincado, J. G.
name: Fragkoudi, F.
name: García-Hernández, D. A.
name: Geisler, D.
name: Lian, J.
name: Majewski, S.
name: Minniti, D.
name: Nitschelm, C.
name: Queiroz, A. B. A.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We use data of $\sim$13,000 stars from the SDSS/APOGEE survey to study the shape of the bulge MDF within the region $|\ell|\leq11^\circ$ and $|b|\leq13^\circ$, and spatially constrained to ${\rm R_{GC}\leq3.5}$ kpc. We apply Gaussian Mixture Modeling and Non-negative Matrix Factorization decomposition techniques to identify the optimal number and the properties of MDF components. We find the shape and spatial variations of the MDF (at ${\rm [Fe/H]\geq-1}$ dex) are well represented as a smoothly varying contribution of three overlapping components located at [Fe/H]=+$0.32$, $-0.17$ and $-0.66$ dex. The bimodal MDF found in previous studies is in agreement with our trimodal assessment once the limitations in sample size and individual measurement errors are taken into account. The shape of the MDF and its correlations with kinematics reveal different spatial distributions and kinematical structure for the three components co-existing in the bulge region. We confirm the consensus physical interpretation of metal-rich stars as associated with the secularly evolved disk into a boxy/peanut X-shape bar. On the other hand, metal-intermediate stars could be the product of in-situ formation at high redshift in a gas-rich environment characterized by violent and fast star formation. This interpretation would help to link a present-day structure with those observed in formation in the center of high redshift galaxies. Finally, metal-poor stars may correspond to the metal-rich tail of the population sampled at lower metallicity from the study of RR Lyrae stars. Conversely, they could be associated with the metal-poor tail of the early thick disc.
description: This article has been accepted for publication in Monthly Notices of the Royal Astronomical Society, Published by Oxford University Press on behalf of the Royal Astronomical Society. 21 pages, 19 Figures
Additional file 4 of Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway
Creators: name: Morimatsu, Maho
name: Yamashita, Erika
name: Seno, Shigeto
name: Sudo, Takao
name: Kikuta, Junichi
name: Mizuno, Hiroki
name: Okuzaki, Daisuke
name: Motooka, Daisuke
name: Ishii, Masaru
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 4: Supplementary Figure 1. Intravital two-photon imaging at different phases of progression. Representative intravital two-photon MIP skull images from C57Bl6 mice 10 days (left), 18 days (middle), and 27 days (right) after AML cell injection (day 0). Green, EGFP-expressing AML cells; red, blood vessels (Alexa Fluor 594); blue, bone tissues (SHG). Scale bar, 50 μm. See also Video 1.
Hypochthonius C. L. Koch 1835
Creators: name: Behan-Pelletier, Valerie M.
name: Lindo, Zoë
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Hypochthoniidae
Hypochthonius

description: Hypochthonius sp.
 Geographic Location and Habitats: BC: Upper Klanawa Mainline site, near Franklin River (Berch et al. 2001); SK: Matador IBP Site, dry mixed prairie (Willard 1974); ON: Sudbury, 20-year tailing site with moss, lichens, grasses, Trembling aspen, Black locust, Jack pine and Red pine (St. John et al. 2002); QC: Mont Tremblant (Behan et al. 1978).
 Family Mesoplophoridae
 Genus Archoplophora van der Hammen, 1959
description: Published as part of Behan-Pelletier, Valerie M. & Lindo, Zoë, 2019, Checklist of oribatid mites (Acari: Oribatida) of Canada and Alaska, pp. 1-180 in Zootaxa 4666 (1) on page 22, DOI: 10.11646/zootaxa.4666.1.1, http://zenodo.org/record/4000595
Glassy dynamics: effective temperatures and intermittencies from a two-state model
Creators: name: Naspreda, M.
name: Reguera, D.
name: Perez-Madrid, A.
name: Rubi, J. M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We show the existence of intermittent dynamics in one of the simplest model of a glassy system: the two-state model, which has been used to explain the origin of the violation of the fluctuation-dissipation theorem. The dynamics is analyzed through a Langevin equation for the evolution of the state of the system through its energy landscape. The results obtained concerning the violation factor and the non-Gaussian nature of the fluctuations are in good qualitative agreement with experiments measuring the effective temperature and the voltage fluctuations in gels and in polymer glasses. The method proposed can be useful to study the dynamics of other slow relaxation systems in which non-Gaussian fluctuations have been observed.
description: 4 pages, 4 figures
Access to research in Cameroon: potential for the democratization of knowledge
Creators: name: Jonas, Randall Anthony
Publisher: name: University of British Columbia
Year: 2009

description: The following research has been carried out in order to assess the current state of access to both print and electronic scholarship at 6 universities in the developing nation of Cameroon and to gather information about the perceptions and needs that students, professors and librarians have regarding open access to scholarly resources through the use of the Internet. This has been done in order to discover how open access via the Internet can make a positive contribution to the scholarly lives of people who find themselves victims of the digital divide and the knowledge gap and to promote the democratization of knowledge access via this mode of information dissemination. Using questionnaires, this research asked 91 participants topical questions regarding these issues and discovered that the importance of increasing both access to technology and research literature is appreciated and supported. The questionnaires were prepared by John Willinsky and Henry Kang. Two librarians from Buea University in Cameroon, Kivin Wirsiy and Rosemary Sutcliffe, were hired to distribute, collect and then send the results back to Vancouver, Canada. The results of this thesis will be combined with the analysis conducted by Kivin Wirsiy and Rosemary Sutcliffe to form a joint international publication of the larger project. What was found as a result of this study is both a source of concern and hope. Even though their access to the Internet was restrained and often at their own personal expenditure, the Cameroonians participating in this study were committed to the use and possibilities of this medium to increase their access to academic literature and at the same time they positively anticipate overcoming the currently inferior state of access by the ameliorating capacities posed by online journals both from abroad and, more so among students, from Africa, for their research and teaching.
Entropy driven formation of a chiral liquid crystalline phase of helical filaments
Creators: name: Barry, Edward
name: Hensel, Zach
name: Shribak, Michael
name: Oldenbourg, Rudolf
name: Dogic, Zvonimir
Publisher: name: arXiv
Year: 2005
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We study the liquid crystalline phase behavior of a concentrated suspension of helical flagella isolated from {\it Salmonella typhimurium}. Flagella are prepared with different polymorphic states, some of which have a pronounced helical character while others assume a rod-like shape. We show that the static phase behavior and dynamics of chiral helices are very different when compared to simpler achiral hard rods. With increasing concentration, helical flagella undergo an entropy driven first order phase transition to a liquid crystalline state having a novel chiral symmetry.
description: 5 pages, 5 figures. submitted to Physical Review Letters. to appear in Phys. Rev. Lett
Generating Sparse Stochastic Processes Using Matched Splines
Creators: name: Dadi, Leello
name: Aziznejad, Shayan
name: Unser, Michael
Publisher: name: arXiv
Year: 2020
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We provide an algorithm to generate trajectories of sparse stochastic processes that are solutions of linear ordinary differential equations driven by Lévy white noises. A recent paper showed that these processes are limits in law of generalized compound-Poisson processes. Based on this result, we derive an off-the-grid algorithm that generates arbitrarily close approximations of the target process. Our method relies on a B-spline representation of generalized compound-Poisson processes. We illustrate numerically the validity of our approach.
Gauge Theory on Fuzzy S^2 x S^2 and Regularization on Noncommutative R^4
Creators: name: Behr, Wolfgang
name: Meyer, Frank
name: Steinacker, Harold
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We define U(n) gauge theory on fuzzy S^2_N x S^2_N as a multi-matrix model, which reduces to ordinary Yang-Mills theory on S^2 x S^2 in the commutative limit N -> infinity. The model can be used as a regularization of gauge theory on noncommutative R^4_θin a particular scaling limit, which is studied in detail. We also find topologically non-trivial U(1) solutions, which reduce to the known "fluxon" solutions in the limit of R^4_θ, reproducing their full moduli space. Other solutions which can be interpreted as 2-dimensional branes are also found. The quantization of the model is defined non-perturbatively in terms of a path integral which is finite. A gauge-fixed BRST-invariant action is given as well. Fermions in the fundamental representation of the gauge group are included using a formulation based on SO(6), by defining a fuzzy Dirac operator which reduces to the standard Dirac operator on S^2 x S^2 in the commutative limit. The chirality operator and Weyl spinors are also introduced.
description: 39 pages. V2-4: References added, typos fixed
Additional file 1 of Respiratory diseases and allergy in farmers working with livestock: a EAACI position paper
Creators: name: Sigsgaard, T.
name: I. Basinas
name: G. Doekes
name: F. De Blay
name: I. Folletti
name: D. Heederik
name: A. Lipinska-Ojrzanowska
name: D. Nowak
name: M. Olivieri
name: S. Quirce
name: M. Raulf
name: J. Sastre
name: V. Schlünssen
name: J. Walusiak-Skorupa
name: A. Siracusa
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. Appendix S1 Search strategy.
Towards gravitationally assisted negative refraction of light by vacuum
Creators: name: Lakhtakia, Akhlesh
name: Mackay, Tom G.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Optics (physics.optics)
subject: Astrophysics (astro-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: Propagation of electromagnetic plane waves in some directions in gravitationally affected vacuum over limited ranges of spacetime can be such that the phase velocity vector casts a negative projection on the time-averaged Poynting vector. This conclusion suggests, inter alia, gravitationally assisted negative refraction by vacuum.
description: 6 pages
Review of Artificial Intelligence Techniques in Imaging Data Acquisition, Segmentation and Diagnosis for COVID-19
Creators: name: Shi, Feng
name: Wang, Jun
name: Shi, Jun
name: Wu, Ziyan
name: Wang, Qian
name: Tang, Zhenyu
name: He, Kelei
name: Shi, Yinghuan
name: Shen, Dinggang
Publisher: name: arXiv
Year: 2020
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: (This paper was submitted as an invited paper to IEEE Reviews in Biomedical Engineering on April 6, 2020.) The pandemic of coronavirus disease 2019 (COVID-19) is spreading all over the world. Medical imaging such as X-ray and computed tomography (CT) plays an essential role in the global fight against COVID-19, whereas the recently emerging artificial intelligence (AI) technologies further strengthen the power of the imaging tools and help medical specialists. We hereby review the rapid responses in the community of medical imaging (empowered by AI) toward COVID-19. For example, AI-empowered image acquisition can significantly help automate the scanning procedure and also reshape the workflow with minimal contact to patients, providing the best protection to the imaging technicians. Also, AI can improve work efficiency by accurate delination of infections in X-ray and CT images, facilitating subsequent quantification. Moreover, the computer-aided platforms help radiologists make clinical decisions, i.e., for disease diagnosis, tracking, and prognosis. In this review paper, we thus cover the entire pipeline of medical imaging and analysis techniques involved with COVID-19, including image acquisition, segmentation, diagnosis, and follow-up. We particularly focus on the integration of AI with X-ray and CT, both of which are widely used in the frontline hospitals, in order to depict the latest progress of medical imaging and radiology fighting against COVID-19.
description: Added journal submission info
Block orbital-selective Mott insulators: a spin excitation analysis
Creators: name: Herbrych, J.
name: Alvarez, G.
name: Moreo, A.
name: Dagotto, E.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a comprehensive study of the spin excitations - as measured by the dynamical spin structure factor $S(q,ω)$ - of the so-called block-magnetic state of low-dimensional orbital-selective Mott insulators. We realize this state via both a multi-orbital Hubbard model and a generalized Kondo-Heisenberg Hamiltonian. Due to various competing energy scales present in the models, the system develops periodic ferromagnetic islands of various shapes and sizes, which are antiferromagnetically coupled. The 2$\times$2 particular case was already found experimentally in the ladder material BaFe$_2$Se$_3$ that becomes superconducting under pressure. Here we discuss the electronic density as well as Hubbard and Hund coupling dependence of $S(q,ω)$ using density matrix renormalization group method. Several interesting features were identified: (1) An acoustic (dispersive spin-wave) mode develops. (2) The spin-wave bandwidth establishes a new energy scale that is strongly dependent on the size of the magnetic island and becomes abnormally small for large clusters. (3) Optical (dispersionless spin excitation) modes are present for all block states studied here. In addition, a variety of phenomenological spin Hamiltonians have been investigated but none matches entirely our results that were obtained primarily at intermediate Hubbard $U$ strengths. Our comprehensive analysis provides theoretical guidance and motivation to crystal growers to search for appropriate candidate materials to realize the block states, and to neutron scattering experimentalists to confirm the exotic dynamical magnetic properties unveiled here, with a rich mixture of acoustic and optical features.
The Study of the Pioneer Anomaly: New Data and Objectives for New Investigation
Creators: name: Turyshev, Slava G.
name: Toth, Viktor T.
name: Kellogg, Larry R.
name: Lau, Eunice. L.
name: Lee, Kyong J.
Publisher: name: arXiv
Year: 2005
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Radiometric tracking data from Pioneer 10 and 11 spacecraft has consistently indicated the presence of a small, anomalous, Doppler frequency drift, uniformly changing with a rate of ~6 x 10^{-9} Hz/s; the drift can be interpreted as a constant sunward acceleration of each particular spacecraft of a_P = (8.74 \pm 1.33) x 10^{-10} m/s^2. This signal is known as the Pioneer anomaly; the nature of this anomaly remains unexplained. We discuss the efforts to retrieve the entire data sets of the Pioneer 10/11 radiometric Doppler data. We also report on the recently recovered telemetry files that may be used to reconstruct the engineering history of both spacecraft using original project documentation and newly developed software tools. We discuss possible ways to further investigate the discovered effect using these telemetry files in conjunction with the analysis of the much extended Doppler data. We present the main objectives of new upcoming study of the Pioneer anomaly, namely i) analysis of the early data that could yield the direction of the anomaly, ii) analysis of planetary encounters, that should tell more about the onset of the anomaly, iii) analysis of the entire dataset, to better determine the anomaly's temporal behavior, iv) comparative analysis of individual anomalous accelerations for the two Pioneers, v) the detailed study of on-board systematics, and vi) development of a thermal-electric-dynamical model using on-board telemetry. The outlined strategy may allow for a higher accuracy solution for a_P and, possibly, will lead to an unambiguous determination of the origin of the Pioneer anomaly.
description: 43 pages, 40 figures, 3 tables, minor changes before publication
Eniochthonius mahunkai Norton and Behan-Pelletier 2007
Creators: name: Behan-Pelletier, Valerie M.
name: Lindo, Zoë
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Eniochthoniidae
Eniochthonius
Eniochthonius mahunkai

description: Eniochthonius cf. mahunkai Norton and Behan-Pelletier, 2007
 Geographic Location and Habitats: ON: near White River (Barreto & Lindo 2018).
description: Published as part of Behan-Pelletier, Valerie M. & Lindo, Zoë, 2019, Checklist of oribatid mites (Acari: Oribatida) of Canada and Alaska, pp. 1-180 in Zootaxa 4666 (1) on page 21, DOI: 10.11646/zootaxa.4666.1.1, http://zenodo.org/record/4000595
Mesoplophora Berlese 1904
Creators: name: Behan-Pelletier, Valerie M.
name: Lindo, Zoë
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Mesoplophoridae
Mesoplophora

description: Mesoplophora sp.
 Geographic Location and Habitats: NS: Cape Breton Highlands NP (Behan-Pelletier 2010).
 Superfamily Protoplophoroidea
 Family Cosmochthoniidae
 Genus Cosmochthonius Berlese, 1910
description: Published as part of Behan-Pelletier, Valerie M. & Lindo, Zoë, 2019, Checklist of oribatid mites (Acari: Oribatida) of Canada and Alaska, pp. 1-180 in Zootaxa 4666 (1) on pages 22-23, DOI: 10.11646/zootaxa.4666.1.1, http://zenodo.org/record/4000595
EXAMINATION OF LEADER COMMUNICATION IN AGRICULTURE
Creators: name: Dajnoki, Krisztina
name: Dajnoki, Krisztina
Publisher: name: Unknown
Year: 2007
Subjects: subject: Farm Management
subject: Institutional and Behavioral Economics
subject: Labor and Human Capital
subject: Teaching/Communication/Extension/Profession
subject: agricultural organisation
subject: leader communication
subject: interactioin examinations

description: My doctoral and research topic was significant in the examination and analysis of leader activities in the framework of a functional, modularly constructed empirical research program of the Department of Management Sciences. I could make statements and correspond about leader activities; these exercises and the influential factors on these activities were studied by the examinations and analyses of leader communication. In this article, I will demonstrate the research I made in on agricultural communication, as a Ph.D. student in the Department of Management Sciences.
title: Η προγνωστική αξία της ανοσοέκφρασης του υποδοχέα επιδερμικού αυξητικού παράγοντα EGFR/ΕrbB σε ασθενείς με μελάνωμα
title: The prognostic value of epidermal growth factor receptor EGFR/ΕrbB immunoexpression in melanoma patients
titleType: AlternativeTitle
Creators: name: Σαλαγιάννη, Γεωργία
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Υποδοχέας επιδερμικού αυξητικού παράγοντα (EGFR)
Πρόγνωση
Μελάνωμα
Βιοδείκτες
Θεραπεία

description: Στον τομέα της ογκολογικής έρευνας, ο προσδιορισμός προγνωστικών δεικτών είναι κρίσιμη διαδικασία, προσφέροντας πολύτιμες πληροφορίες για την εξέλιξη της νόσου, τη θεραπευτική ανταπόκριση και την έκβαση των ασθενών. Το μελάνωμα, μια από τις πιο συχνές και επιθετικές δερματικές κακοήθειες, χαρακτηρίζεται από την πρώιμη μετάσταση και αποτελεί τον πιο θανατηφόρο καρκίνο του δέρματος. Ο υποδοχέας του επιδερμικού αυξητικού παράγοντα (EGFR), επίσης γνωστός ως ErbB-1, είναι μια κινάση τυροσίνης που ανήκει στην οικογένεια ErbB. Τα τελευταία χρόνια, οι μοριακές μελέτες έχουν ρίξει φως στα περίπλοκα μονοπάτια που διέπουν την ανάπτυξη και την εξέλιξη του μελανώματος, μεταξύ των οποίων ο EGFR έχει αναδειχθεί να παίζει σημαντικό ρόλο. Σκοπός της παρούσας διπλωματικής εργασίας ήταν η ανασκόπηση και σύνθεση της υπάρχουσας βιβλιογραφίας σχετικά με την προγνωστική σημασία του EGFR στο μελάνωμα. Μέσω συστηματικής ανάλυσης και κριτικής αξιολόγησης πειραματικών δεδομένων, η εργασία εστίασε στη διερεύνηση των μοριακών μηχανισμών που εμπλέκονται στις προγνωστικές επιπτώσεις του EGFR, καθώς και στη χρησιμότητά του ως βιοδείκτη για τη θεραπευτική ανταπόκριση. Τα ευρήματα δείχνουν ότι η έκφραση του EGFR στο μελάνωμα παίζει σημαντικό ρόλο στην εξέλιξη, κινητικότητα και πρωτεολυτική ικανότητα των καρκινικών κυττάρων, προάγοντας τη μετάσταση και επηρεάζοντας αρνητικά την πρόγνωση. Ο EGFR σχετίζεται με το πάχος του όγκου, τη μετάσταση και την επιθετικότητα του μελανώματος, ενώ ρυθμίζει την ανοσολογική απόκριση. Επιπλέον, κρίσιμοι μηχανισμοί που επηρεάζουν την εξέλιξη του μελανώματος και προσφέρουν νέες θεραπευτικές δυνατότητες αναδεικνύονται από την ανασκόπηση. Συγκεκριμένα, η μείωση της πρωτεΐνης KIF22 καταστέλλει τον πολλαπλασιασμό και τη γλυκόλυση, ενώ προάγει την απόπτωση μέσω απενεργοποίησης του EGFR/STAT3. Η IGFBP2 ρυθμίζει το PD-L1 μέσω του άξονα EGFR STAT3, ενώ ο NRF2 είναι απαραίτητος για την ενεργοποίηση του EGFR/AKT. Επιπλέον, η ανασκόπηση αποκαλύπτει τη σύνθετη επίδραση του EGFR στην ανθεκτικότητα του μελανώματος, καθώς κύτταρα με υψηλή έκφραση EGFR δείχνουν ανθεκτικότητα στη βεμουραφενίμπη, συσχετιζόμενη με αυξημένη ενεργοποίηση των Erk, FRA-1 και PD-L1. Η απώλεια της ACK1 και του MITF ενισχύει την σηματοδότηση του EGFR, ενώ μη αναστρέψιμοι EGFR-TKIs, κουρκουμίνη, ροσμαρινικό οξύ και αναστολείς BET προτείνονται ως νέες θεραπευτικές στρατηγικές για την αντιμετώπιση της ανθεκτικότητας. Συμπερασματικά, ο EGFR στο μελάνωμα έχει σημαντική προγνωστική αξία, επηρεάζοντας την εξέλιξη, την επιθετικότητα και την ανθεκτικότητα του καρκίνου.
A theoretical framework for comprehensive modeling of steadily fed evaporating droplets and the validity of common assumptions
Creators: name: Akkus, Yigit
name: Cetin, Barbaros
name: Dursunkaya, Zafer
Publisher: name: arXiv
Year: 2020
Subjects: subject: Applied Physics (physics.app-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: A theoretical framework is established to model the evaporation from continuously fed droplets, promising tools in the thermal management of high heat flux electronics. Using the framework, a comprehensive model is developed for a hemispherical water droplet resting on a heated flat substrate incorporating all of the relevant transport mechanisms: buoyant and thermocapillary convection inside the droplet and diffusive and convective transport of vapor in the gas domain. At the interface, mass, momentum, and thermal coupling of the phases are also made accounting for all pertinent physical aspects including several rarely considered interfacial phenomena such as Stefan flow of gas and the radiative heat transfer from interface to the surroundings. The model developed utilizes temperature dependent properties in both phases including the density and accounts for all relevant physics including Marangoni flow, which makes the model unprecedented. Moreover, utilizing this comprehensive model, a nonmonotonic interfacial temperature distribution with double temperature dips is discovered for a hemispherical droplet having internal convection due to buoyancy in the case of high substrate temperature. Proposed framework is also employed to construct several simplified models adopting common assumptions of droplet evaporation and the computational performance of these models, thereby the validity of commonly applied simplifying assumptions, are assessed. Benchmark simulations reveal that omission of gas flow, i.e. neglecting convective transport in gas phase, results in the underestimation of evaporation rates by 23-54%. When gas flow is considered but the effect of buoyancy is modeled using Boussinesq approximation instead of assigning temperature dependent density throughout the gas domain, evaporation rate can be underestimated by up to 16%.
ANALYSIS OF THE EXPECTED INCOME OF SEVERAL FAMILY TYPES
Creators: name: Nagy, Adrian Szilard
name: Nagy, Adrian Szilard
Publisher: name: Unknown
Year: 2007
Subjects: subject: Agribusiness
subject: Consumer/Household Economics
subject: Farm Management
subject: income of family farms

description: In this essay, I deal with the problem of expected income of family holdings. Despite the fact that expected income is mentioned in numerous specialist publications and in political declarations, its definition and method of calculation are not detailed. On the basis of my research, I define the notion of expected income and I determine its scale concerning different family types for the year 2006, on the basis of a survey I carried out among 198 agriculturists.
Modulation of the local density of states within the $d$-density wave theory in the underdoped cuprates
Creators: name: Ghosal, Amit
name: Kopp, Angela
name: Chakravarty, Sudip
Publisher: name: arXiv
Year: 2004
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The low temperature scanning tunneling microscopy spectra in the underdoped regime is analyzed from the perspective of coexisting $d$-density wave and d-wave superconducting states. The calculations are carried out in the presence of a low concentration of unitary impurities and within the framework of the fully self-consistent Bogoliubov-de Gennes theory, which allows local modulations of the magnitude of the order parameters in response to the impurities. Our theory captures the essential aspects of the experiments in the underdoped BSCCO at very low temperatures.
description: 4 pages, 4 eps figures, RevTex4. New added material as well as references
Analysis of the second order BDF scheme with variable steps for the molecular beam epitaxial model without slope selection
Creators: name: Liao, Hong-lin
name: Song, Xuehua
name: Tang, Tao
name: Zhou, Tao
Publisher: name: arXiv
Year: 2020
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65M06, 65M12

description: In this work, we are concerned with the stability and convergence analysis of the second order BDF (BDF2) scheme with variable steps for the molecular beam epitaxial model without slope selection. We first show that the variable-step BDF2 scheme is convex and uniquely solvable under a weak time-step constraint. Then we show that it preserves an energy dissipation law if the adjacent time-step ratios $r_k:=τ_k/τ_{k-1}<3.561.$ Moreover, with a novel discrete orthogonal convolution kernels argument and some new discrete convolutional inequalities, the $L^2$ norm stability and rigorous error estimates are established, under the same step-ratios constraint that ensuring the energy stability., i.e., $0
description: 20 pages, 14 figures, 1 table
KEY ASPECTS OF INVESTMENT ANALYSIS
Creators: name: Nabradi, Andras
name: Szollosi, Laszlo
name: Nabradi, Andras
name: Szollosi, Laszlo
Publisher: name: Unknown
Year: 2007
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Financial Economics
subject: net present value
subject: internal rate of return
subject: profitability index
subject: payback period

description: This paper reviewed principally accepted methods applied to investment analysis. To describe every aspect of investment analysis fully would require far more space than available here, so we highlight only of few of its aspects. This study collects several well-known bibliographies, contrasts them with each other and provides explanations for having done so. There are many questions about which authors and companies agree, including about how to apply certain methods, but on others there is disagreement. Four dynamic methods (Net Present Value, Internal Rate of Return, Profitability Index, and Discounted Payback Period) are demonstrated from the viewpoint of application. Moreover, this study clarifies several sensitive questions, such as handling income taxes, inflation and uncertainty. Other examined issues are only mentioned at the end of this paper, and we will publish on these more thoroughly at a later date.
LAND REGULATION IN THE EUROPEAN UNION AND HUNGARY
Creators: name: Szabo, Erika
name: Szabo, Erika
Publisher: name: Unknown
Year: 2007
Subjects: subject: Agricultural and Food Policy
subject: Environmental Economics and Policy
subject: Farm Management
subject: Land Economics/Use
subject: land regulation
subject: land law

description: Land, as it constitutes one of the bases of agricultural production, has a special position in the economic-judiciary surroundings of states. In Hungarian history, land ownership has undergone many radical transitions. The decade starting from the political and land regulation reform is a short time in land tenure. In spite of it, there have been several important changes in land ownership structure. In the 1970s and 80s, large agricultural firms, especially co-operatives and state farms, were common in Hungary. State hegemony was typical of land ownership and use, with rather small, privately owned parcels. Since privatization began after 1989, this tendency has changed, with land owned by farmers. In the following article, I am going to review the laws regulating land ownership and land use in Hungary and in the European Union.
OPPORTUNITIES FOR THE INCLUSION OF LESS-FAVOURED AREAS IN THE NORTHERN GREAT PLAIN REGION
Creators: name: Bittner, Beata
name: Bittner, Beata
Publisher: name: Unknown
Year: 2007
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Environmental Economics and Policy
subject: Farm Management
subject: Land Economics/Use
subject: less-favoured areas
subject: small regions in the northern great plain

description: Agricultural economics and its part, rural economics plays a determining role in Hungary. Most rural families perform self-sufficient farm production for a living. In the present conditions of infrastructure and human resources, there are regions where the only rural alternative for employment is agriculture. There are significant differences among the regions considering natural resources and equipment available for farm production, and these differences affect potential income (Vörös et al. 1999). The primary aim of the European Union is to reduce such differences among the regions.The new research program of the University of Debrecen tackles the fundamental questions of regional development through the research and management of social asymmetries by using economic and other relevant tools. This program also provides suggestions for facilitating the development of less-favoured areas.
title: Πες μου ένα παραμύθι! Η θεραπευτική δύναμη της αφήγησης παραμυθιών σε συνδυασμό με την τέχνη στην ψηφιακή εποχή.
title: Tell me a fairy tale! The healing power of the fairy tales combined with the art in the digital age.
titleType: AlternativeTitle
Creators: name: Κωτσοπούλου, Αγγελική
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Παραμυθοθεραπεία
Βιβλιοθεραπεία
Αρχέτυπα
Σύμβολα
Ψηφιακή αφήγηση

description: Εισαγωγή: Τα παραμύθια κατέχουν αξιοσημείωτο ρόλο και εξυπηρετούν παιδαγωγικούς και εκπαιδευτικούς σκοπούς. Μέσω των παραμυθιών τα παιδιά προσεγγίζουν την γνώση και μαθαίνουν αβίαστα και δημιουργικά ενώ παράλληλα καλλιεργούν την φαντασία τους και ακονίζουν την μνήμη και την αντίληψή τους. Από παραμύθια και μύθους-πολλές περιπέτειες, ήρωες, προσωποποιημένα ζώα, μαγεμένα δάση-τα παιδιά αποκτούν επιπλέον εμπειρίες, συναισθήματα και σκέψεις, μαθαίνοντας να αντιμετωπίζουν τις αναστολές και τη συστολή. Σύμφωνα με την ψυχαναλυτική ερμηνεία οι παιδικές ιστορίες οδηγούν τα παιδιά σε ένα βαθύ επίπεδο συνείδησης, που ασχολείται με τα θεμελιώδη ανθρώπινα ερωτήματα που εκφράζονται στη γλώσσα των συμβόλων. Πέρα από τους εκπαιδευτικούς σκοπούς τους τα παραμύθια μπορεί να λειτουργήσουν ως θεραπευτικό εργαλείο. Τόσο η παραδοσιακή αφήγηση ιστοριών όσο και η ψηφιακή αφήγηση επιτρέπει στα παιδιά να εκφράσουν και να αντιμετωπίσουν τους φόβους τους. Καθώς το περιεχόμενο των παραμυθιών είναι εξαιρετικά συμβολικό, βοηθά στη μετατροπή της εμπειρίας του παιδιού σε χαρακτήρες και καταστάσεις μέσα στην ιστορία, προωθώντας την καλύτερη κατανόηση των συναισθημάτων και των συμπεριφορών του. Σκοπός: Σκοπός της παρούσας εργασίας είναι να αναδείξει την βαθιά ριζωμένη αξία των παραμυθιών στην συνολική ανάπτυξη των μικρών παιδιών καθώς δεν αποτελούν μόνο πηγή διασκέδασης αλλά και ισχυρά εργαλεία που ενθαρρύνουν την ανάπτυξη της γνώσης, των συναισθημάτων και της κοινωνικοποίησης προς ένα ολοκληρωμένο άτομο. Επίσης, να αναδείξει την αξία και συμβολή της παραμυθοθεραπείας, ως μορφή τέχνης, στην ολόπλευρη ανάπτυξη των παιδιών. Μέθοδος: Πραγματοποιήθηκε αναζήτηση βάσει βιβλιογραφικής ανασκόπησης που εμπεριέχει τις πιο αντιπροσωπευτικές μελέτες του θέματος και οι οποίες παρουσιάζονται με το σύστημα APA. Η βιβλιογραφική ανασκόπηση έγινε σε Google Scholar, Embase και PubMed και από τις 250 μελέτες που εντοπίστηκαν, επιλέχθηκαν τελικώς 25 βάση καταλληλότητας. Αποτελέσματα: Πράγματι η βιβλιοθεραπεία μπορεί να βελτιώσει την αντίληψη των προσωπικών αξιών, τις διαπροσωπικές σχέσεις και την αποδοχή των ατομικών διαφορών. Επίσης, μπορεί να μειώσει τα συμπτώματα του κοινωνικού άγχους και να βελτιώσει την προσαρμογή στην ασθένεια. Η δύναμη της ακρόασης προκαλεί κάθαρση με αποτέλεσμα λιγότερο άγχος και αυτοεκτίμηση, βοηθώντας έτσι το παιδί να αντιμετωπίσει κάθε αντιξοότητα και να επικοινωνήσει τα συναισθήματα του. Συμπεράσματα: Στην εποχή της παγκοσμιοποίησης, με τις βαθιές κοινωνικοοικονομικές αλλαγές και την κατάρρευση του παραδοσιακού κοινωνικού ιστού, θα μπορούσαν τα παραμύθια να αποτελέσουν ένα χρήσιμο εργαλείο για την προώθηση της ατομικής ανάπτυξης, της κοινωνικής συνοχής και της βιώσιμης ανάπτυξης.
Infinitely many universally tight contact manifolds with trivial Ozsvath-Szabo contact invariants
Creators: name: Ghiggini, Paolo
Publisher: name: arXiv
Year: 2005
Subjects: subject: Geometric Topology (math.GT)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 57R17, 57R57

description: In this article we present infinitely many 3-manifolds admitting infinitely many universally tight contact structures each with trivial Ozsvath-Szabo contact invariants. By known properties of these invariants the contact structures constructed here are non weakly symplectically fillable.
description: This is the version published by Geometry & Topology on 2 April 2006
Regulación de la autogeneración de energía eléctrica en Colombia – incentivos para su desarrollo por parte de productores de petróleo y/o gas natural
Creators: name: Cadena Berdugo, Johan Sebastián
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Derecho minero - Aspectos jurídicos
subject: Petróleo - Colombia
subject: Energía - Legislación
subject: Autogeneración
subject: Energía Eléctrica
subject: Incentivos regulatorios
subject: Productores de petróleo

description: Conforme avanza la regulación para desarrollar la actividad de autogeneración en Colombia, se observa que pueden existir incentivos regulatorios para que, bajo dicha actividad, empresas productoras de petróleo y/o gas natural vendan energía en el Mercado de Energía Mayorista. Este trabajo analiza la existencia de dichos incentivos. Para ello, se realiza una presentación detallada de la regulación de la actividad de autogeneración en Colombia, la cual permitirá identificar tres (3) condiciones que incentivan que empresas productoras de Petróleo y/o Gas Natural vendan energía directamente en el Mercado de Energía Mayorista a través de la figura de la autogeneración, así como una condición que limita dicha venta. Posteriormente, se analiza como aplicarían las condiciones previamente mencionadas a Ecopetrol, que es la principal empresa de producción de petróleo y gas en Colombia. Como resultado de ese análisis, se encuentra que la regulación actual permite que Ecopetrol pueda vender energía directamente en el Mercado de Energía Mayorista, a través de la figura de la autogeneración, con cierta flexibilidad e incentivos. En razón de lo anterior, también se analizan algunas medidas regulatorias que se podrían tomar para evitar el uso indebido de la figura de la autogeneración por parte de Ecopetrol.
description: Regarding the self-generation activity in Colombia, there may be regulatory incentives for oil and/or natural gas producing companies to sell energy in the Wholesale Energy Market under this activity. This paper analyzes the existence of such incentives. For this purpose, a detailed presentation of the regulation of the self-generation activity in Colombia is made. This presentation will deploy the basis for identifying three (3) conditions that encourage oil and/or natural gas producers to sell energy directly in the Wholesale Energy Market through the figure of self-generation. Another condition that limits such sale will be identified as well. These conditions will be analyzed in the case of Ecopetrol, which is the main oil and gas production company in Colombia. As a result of this analysis, it is found that the current regulation allows Ecopetrol to sell energy directly in the Wholesale Energy Market, through the figure of self-generation, with certain flexibility and incentives. Taking this into account, this work will present some regulatory measures that could be taken to avoid the improper use of the figure of self-generation by Ecopetrol.
Cosmochthonius Berlese 1910
Creators: name: Behan-Pelletier, Valerie M.
name: Lindo, Zoë
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Cosmochthoniidae
Cosmochthonius

description: Cosmochthonius sp.
 Geographic Location: BC: Osoyoos, Haynes Lease (Behan-Pelletier et al. 1987b); ON: 3 km south of Guelph (Broadbent & Tomlin 1979).
 Family Haplochthoniidae
 Genus Haplochthonius Willmann, 1930
description: Published as part of Behan-Pelletier, Valerie M. & Lindo, Zoë, 2019, Checklist of oribatid mites (Acari: Oribatida) of Canada and Alaska, pp. 1-180 in Zootaxa 4666 (1) on page 23, DOI: 10.11646/zootaxa.4666.1.1, http://zenodo.org/record/4000595
RISK AND RISK MANAGEMENT IN HUNGARIAN SHEEP PRODUCTION
Creators: name: Nabradi, Andras
name: Madai, Hajnalka
name: Nabradi, Andras
name: Madai, Hajnalka
Publisher: name: Unknown
Year: 2007
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Farm Management
subject: Food Security and Poverty
subject: risk sources
subject: risk management
subject: sheep farming
subject: EU accession
subject: field survey

description: The aim of this paper is to give an overview of the risk attitudes of Hungarian sheep producers regarding the changes they have had to go through since the political changes of 1989–1990. Moreover, the objective of this study is to strengthen the empirical basis for risk analysis by identifying the importance of farmers’ risk attitudes. The results of a nationwide survey of over 500 sheep farmers presented a framework of risk attitudes, risk sources and applied risk management techniques of livestock producers.
„GREEN” PUBLIC RELATIONS: PUBLIC RELATIONS IN THE SECTOR OF PRODUCTS AND SERVICES FOR POLISH AGRICULTURE
Creators: name: Wlodarski, Sebastian
name: Wlodarski, Sebastian
Publisher: name: Unknown
Year: 2007
Subjects: subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Environmental Economics and Policy
subject: Farm Management
subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: public relations
subject: polish agriculture

description: The field of Public Relations has undoubtedly been assuming growing importance in Poland. Understood as an element of marketing communication or a function of company management, it has a significant impact on company’s external and internal environment. According to Puls Biznesu3 the value of the Polish PR market amounted to 250m PLN in 2005, which is a 20% increase as compared to 2004. According to the author Urszula S´wiatl⁄owska, “the turnover of PR agencies is growing and even smaller companies demonstrate their interest in the services”. Considering this, it can be assumed that PR activities will soon be initiated by many smaller Polish companies, often connected with the agricultural sector. The change discussed by the authors of the article reflects the phenomenon of PR’s growing importance among other communication channels in Poland.
Deep Generative Modeling for Mechanistic-based Learning and Design of Metamaterial Systems
Creators: name: Wang, Liwei
name: Chan, Yu-Chin
name: Ahmed, Faez
name: Liu, Zhao
name: Zhu, Ping
name: Chen, Wei
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Metamaterials are emerging as a new paradigmatic material system to render unprecedented and tailorable properties for a wide variety of engineering applications. However, the inverse design of metamaterial and its multiscale system is challenging due to high-dimensional topological design space, multiple local optima, and high computational cost. To address these hurdles, we propose a novel data-driven metamaterial design framework based on deep generative modeling. A variational autoencoder (VAE) and a regressor for property prediction are simultaneously trained on a large metamaterial database to map complex microstructures into a low-dimensional, continuous, and organized latent space. We show in this study that the latent space of VAE provides a distance metric to measure shape similarity, enable interpolation between microstructures and encode meaningful patterns of variation in geometries and properties. Based on these insights, systematic data-driven methods are proposed for the design of microstructure, graded family, and multiscale system. For microstructure design, the tuning of mechanical properties and complex manipulations of microstructures are easily achieved by simple vector operations in the latent space. The vector operation is further extended to generate metamaterial families with a controlled gradation of mechanical properties by searching on a constructed graph model. For multiscale metamaterial systems design, a diverse set of microstructures can be rapidly generated using VAE for target properties at different locations and then assembled by an efficient graph-based optimization method to ensure compatibility between adjacent microstructures. We demonstrate our framework by designing both functionally graded and heterogeneous metamaterial systems that achieve desired distortion behaviors.