cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Spin-Orbit Torque and Nernst Eﬀect in Bi-Sb/Co Heterostructures
Creators: name: Roschewsky, Niklas
name: Walker, Emily S.
name: Muschinske, Sarah E.
name: Hellman, Francis
name: Bank, Seth R.
name: Salahuddin, Sayeef
Publisher: name: The University of Texas at Austin
Year: 2018
Subjects: Nernst
Bi-Sb/Co

description: Harmonic measurements of the longitudinal and transverse voltages in Bi-Sb/Co bilayers are presented. A large second harmonic voltage signal due to the ordinary Nernst eﬀect is observed. In experiments where a magnetic ﬁeld is rotated in the ﬁlm plane, the ordinary Nernst eﬀect shows the same angular dependence in the transverse voltage as the damping-like spin-orbit torque and in the longitudinal voltage as the unidirectional spin-Hall magneto-resistance respectively. Therefore, the ordinary Nernst eﬀect can be a spurious signal in spin-orbit torque measurements, leading to an overestimation of the spin-Hall angle in topological insulators or semimetals.
Supplemental Tables.pdf
Creators: name: van Reenen, Kees
Publisher: name: figshare
Year: 2021
Subjects: subject: 70299 Animal Production not elsewhere classified
subject: FOS: Animal and dairy science

description: Supplemental Tables S1, S2 and S3 of research article entitled 'Calf and dam characteristics and calf transport age affect immunoglobulin titers and hematological parameters of veal calves', Journal of Dairy Science, https://doi.org/10.3168/jds.2021-20636.
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
Creators: name: Pausch, M.H.
name: Herlitze, S.
name: Roth, B.L.
name: Li, X.
name: Armbruster, B.N.
Publisher: name: National Academy of Sciences
Year: 2007

description: We evolved muscarinic receptors in yeast to generate a family of G protein-coupled receptors (GPCRs) that are activated solely by a pharmacologically inert drug-like and bioavailable compound (clozapine-N-oxide). Subsequent screening in human cell lines facilitated the creation of a family of muscarinic acetylcholine GPCRs suitable for in vitro and in situ studies. We subsequently created lines of telomerase-immortalized human pulmonary artery smooth muscle cells stably expressing all five family members and found that each one faithfully recapitulated the signaling phenotype of the parent receptor. We also expressed a Gi-coupled designer receptor in hippocampal neurons (hM4D) and demonstrated its ability to induce membrane hyperpolarization and neuronal silencing. We have thus devised a facile approach for designing families of GPCRs with engineered ligand specificities. Such reverse-engineered GPCRs will prove to be powerful tools for selectively modulating signal-transduction pathways in vitro and in vivo.
Ethnobotany in Mexico: An Annotated Bibliography
Creators: name: Aguirre, Hervé Gabriel
Publisher: name: Benson Latin American Collection
Year: 1997
Subjects: Indigenous peoples
Botany--Mexico
Mexico

description: The discovery of the New World resulted in the discovery and subsequent utilization of many new species of plants, such as potato, avocado, chocolate, and coca. Ethnobotany, the study of the use of plants by native people and the relationship to their environment, has been a part of the literature of the New World since the sixteenth century. Bernardino de Sahagún, a Franciscan friar, was first to examine the plant use of the Nahua. Since then, many others have studied the relationship of the people of Mexico to their environment. The publications listed here are located in the Benson Latin American Collection stacks, unless otherwise indicated.
Entropy/Area spectra of the charged black hole from quasinormal modes
Creators: name: Wei, Shao-Wen
name: Liu, Yu-Xiao
name: Yang, Ke
name: Zhong, Yuan
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: With the new physical interpretation of quasinormal modes proposed by Maggiore, the quantum area spectra of black holes have been investigated recently. Adopting the modified Hod's treatment, results show that the area spectra for black holes are equally spaced and the spacings are in a unified form, $\triangle A=8π\hbar$, in Einstein gravity. On the other hand, following Kunstatter's method, the studies show that the area spectrum for a nonrotating black hole with no charge is equidistant. And for a rotating (or charged) black hole, it is also equidistant and independent of the angular momentum $J$ (or charge $q$) when the black hole is far from the extremal case. In this paper, we mainly deal with the area spectrum of the stringy charged Garfinkle-Horowitz-Strominger black hole, originating from effective action that emerges in the low-energy string theory. We find that both methods give the same results-that the area spectrum is equally spaced and does not depend on the charge $q$. Our study may provide new insights into understanding the area spectrum and entropy spectrum for stringy black holes.
description: 13 pages, no figures
Additional file 3 of DTX-P7, a peptide–drug conjugate, is highly effective for non-small cell lung cancer
Creators: name: Jiang, Yao
name: Huang, Wei
name: Sun, Xiaojiao
name: Yang, Xiaozhou
name: Wu, Youming
name: Shi, Jiaojiao
name: Zheng, Ji
name: Fan, Shujie
name: Liu, Junya
name: Wang, Jun
name: Liang, Zhen
name: Yang, Nan
name: Liu, Zhenming
name: Liu, Yanyong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Additional file 3: Supplementary Figure S2. Biodistribution of DTX-P7 in nude mice bearing A549 xenograft tumor. DTX-P7 was quantified by free DTX released from the conjugate. a) Plasma concentration of DTX and DTX-P7 in plasma samples throughout 72-h treatment. b-e) Distribution of DTX in the heart, liver, spleen, lungs, kidneys, and brain in 1 h (b), 2 h (c), 4 h (d) and 8 h (e) after DTX or DTX-P7 was administrated to mice implanted with A549 xenograft tumor. Data are given as mean ± SD (n = 3). * p < 0.05 vs. DTX group.
Inverse design of multicomponent assemblies
Creators: name: Piñeros, William D.
name: Lindquist, Beth A.
name: Jadrich, Ryan B.
name: Truskett, Thomas M.
Publisher: name: AIP Publishing
Year: 2018
Subjects: design

description: Inverse design can be a useful strategy for discovering interactions that drive particles to spontaneously self-assemble into a desired structure. Here, we extend an inverse design methodology—relative entropy optimization—to determine isotropic interactions that promote assembly of targeted multi- component phases, and we apply this extension to design interactions for a variety of binary crystals ranging from compact triangular and square architectures to highly open structures with dodecago- nal and octadecagonal motifs. We compare the resulting optimized (self- and cross) interactions for the binary assemblies to those obtained from optimization of analogous single-component systems. This comparison reveals that self-interactions act as a “primer” to position particles at approxi- mately correct coordination shell distances, while cross interactions act as the “binder” that reﬁnes and locks the system into the desired conﬁguration. For simpler binary targets, it is possible to successfully design self-assembling systems while restricting one of these interaction types to be a hard-core-like potential. However, optimization of both self- and cross interaction types appears necessary to design for assembly of more complex or open structures.
Design of two-dimensional particle assemblies using isotropic pair interactions with an attractive well
Creators: name: Jadrich, Ryan B.
name: Truskett, Thomas M.
Publisher: name: AIP Publishing
Year: 2017
Subjects: isotrope

description: Using ground-state and relative-entropy based inverse design strategies, isotropic interactions with an attractive well are determined to stabilize and promote assembly of particles into two-dimensional square, honeycomb, and kagome lattices. The design rules inferred from these results are discussed and validated in the discovery of interactions that favor assembly of the highly open truncated-square and truncated-hexagonal lattices.
title: Environmental and Social monitoring in existing building structures – results of a case study within several historical buildings
Creators: name: Redlein, Alexander
name: Thrainer, Lisa
Publisher: name: TU Wien
Year: 2022
Subjects: ESG
Sustainability reporting and real-time monitoring
Technology platforms for optimal energy management
Human-centric Internet of Things solutions
Internet of Things (IoT)
Big Data
Analytics
Artificial Intelligence (AI)

description: One year ago the European Union defined the Environmental, Social and Governance (ESG) directive to foster investment in sustainability. This directive asks for energy monitoring / optimization and actions to foster human well-being. To cover that demand especially historical buildings in Europe need solutions in these respects, to be more energy efficient and at the same time to safeguard the well-being of its users. These buildings have almost no building automation installed. So, the basic prerequisite to identify high energy consumers valid usage data is not available. For that, the following research questions have to be answered: Which data is necessary to reach both, the environmental and social goals? How can data be captured in a valid and efficient way? How can data be made available to optimize energy usage and well-being? To answer these questions, a literature research was executed to define the relevant parameters. Firstly, based on the results of that step and a previous mixed-methods-research project, the relevant tools and the IT architecture were defined. Secondly, based on the ESG-reporting demands, data structure and relevant building structures were defined. Thirdly, a case study was conducted, which is based on the previously defined IT architecture, using IoT measuring devices, two different databases and two analytic tools. As a result, this paper presents the final decision on the database and the analytics tool, based on the users’ interaction and feedback of the case study.
Latina and Latino Literature: Anthologies of the 1990s, A Selected Bibliography
Creators: name: Gutiérrez, Margo
Publisher: name: Benson Latin American Collection
Year: 1998
Subjects: Latin American literature
Political culture--Latin America
Latin America

description: Latino literature in the 1990s has come into its own, finally recognized by mainstream publishers as a legitimate, indeed integral, part of American letters. In addition to major publishing houses, small and university presses as well as recognized Hispanic or Latino publishers continue to provide an eager and growing reading public with the rich and diverse literary expressions that make up the Latina and Latino experience. This bibliography makes no attempt to be comprehensive or all-inclusive; it is merely meant to provide readers with a sampling of titles published this decade, many of which are still in print. In general, theater has been omitted unless included in works with other genres. Thanks to R. Joseph Rodríguez and Amanda Salinas for their assistance.
A pair of new oxindole alkaloids isolated from Uncaria macrophylla
Creators: name: Liang, Xin-Xin
name: Yang, Jin-Xuan
name: Li, Jian-Mei
name: Huang, Jia-Bi
name: Yang, Liu-Meng
name: Sun, Tian-Tian
name: Luo, Rong-Hua
name: Xiao, Wei-Lie
name: Zheng, Yong-Tang
name: Li, Xiao-Li
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: A pair of new oxindole alkaloids, named macrophyllines C (1) and D (2), together with two known oxindole alkaloids isorhynchophylline (3) and corynoxine (4) were isolated from Uncaria macrophylla. Their structures were elucidated based on detailed spectroscopic analysis and by comparison with literature data. In addition, all the isolates were tested for their anti-HIV activities and cytotoxicities in C8166 cells and compounds 2–4 showed weak anti-HIV activities with EC50 values of 11.31 ± 3.29 μM, 18.77 ± 6.14 μM and 30.02 ± 3.73 μM, respectively.
Specialized Bilingual Dictionaries
Creators: name: Schroer, Craig
Publisher: name: Benson Latin American Collection
Year: 1998
Subjects: Spanish language--Idioms--Dictionaries--English
Spanish language--Dictionaries
Portuguese language--Dictionaries

description: This bibliography offers a cross-section of bilingual dictionaries devoted to specific subjects or to those with special features (such as pictorial dictionaries) with a focus on those which are most up-to-date. In a few cases the items listed may not be recent but are deemed of significant value for other reasons (e.g., authoritative reference works which have not been updated). Bilingual dictionaries of a general nature are not included but may be located by searching the online catalog by subject under "Spanish language-Dictionaries-English;" "English language-Dictionaries-Portuguese;" etc.
Additional file 18 of CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease
Creators: name: Yu, Dahyun
name: Zarate, Nicole
name: White, Angel
name: Coates, De’jah
name: Tsai, Wei
name: Nanclares, Carmen
name: Cuccu, Francesco
name: Yue, Johnny S.
name: Brown, Taylor G.
name: Mansky, Rachel H.
name: Jiang, Kevin
name: Kim, Hyuck
name: Nichols-Meade, Tessa
name: Larson, Sarah N.
name: Gundry, Katherine
name: Zhang, Ying
name: Tomas-Zapico, Cristina
name: Lucas, Jose J.
name: Benneyworth, Michael
name: Öz, Gülin
name: Cvetanovic, Marija
name: Araque, Alfonso
name: Gomez-Pastor, Rocio
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 18. Supplementary Methods.
title: Attention Aided CSI Wireless Localization
Creators: name: Salihu, Artan
name: Schwarz, Stefan
name: Rupp, Markus
Publisher: name: TU Wien
Year: 2022
Subjects: Attention
Deep Learning
Localization
Massive MIMO
Transformer

description: Deep neural networks (DNNs) have become a popular approach for wireless localization based on channel state information (CSI). A common practice is to use the raw CSI in the input and allow the network to learn relevant channel representations for mapping to location information. However, various works show that raw CSI can be very sensitive to system impairments and small changes in the environment. On the contrary, hand-designing features may hinder the limits of channel representation learning of the DNN. In this work, we propose attention-based CSI for robust feature learning. We evaluate the performance of attended features in centralized and distributed massive MIMO systems for ray-tracing channels in two non-stationary railway track environments. By comparison to a base DNN, our approach provides exceptional performance.
p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling
Creators: name: Brüning, J.C.
name: Deutch, A.Y.
name: Hufeisen, S.J.
name: Garcia, B.G.
name: Leahy, P.
name: Roth, B.L.
name: Kroeze, W.K.
name: Sheffler, D.J.
Publisher: name: National Academy of Sciences
Year: 2006

description: G protein-coupled receptors (GPCRs) are essential for normal central CNS function and represent the proximal site(s) of action for most neurotransmitters and many therapeutic drugs, including typical and atypical antipsychotic drugs. Similarly, protein kinases mediate many of the downstream actions for both ionotropic and metabotropic receptors. We report here that genetic deletion of p90 ribosomal S6 kinase 2 (RSK2) potentiates GPCR signaling. Initial studies of 5-hydroxytryptamine (5-HT)2A receptor signaling in fibroblasts obtained from RSK2 wild-type (+/+) and knockout (-/-) mice showed that 5-HT 2A receptor-mediated phosphoinositide hydrolysis and both basal and 5-HT-stimulated extracellular signal-regulated kinase 1/2 phosphorylation are augmented in RSK2 knockout fibroblasts. Endogenous signaling by other GPCRs, including P2Y-purinergic, PAR-1-thrombinergic, β1-adrenergic, and bradykinin-B receptors, was also potentiated in RSK2-deficient fibroblasts. Importantly, reintroduction of RSK2 into RSK2-/-fibroblasts normalized signaling, thus demonstrating that RSK2 apparently modulates GPCR signaling by exerting a "tonic brake" on GPCR signal transduction. Our results imply the existence of a novel pathway regulating GPCR signaling, modulated by downstream members of the extracellular signal-related kinase/ mitogen-activated protein kinase cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is manifested by mental retardation, growth deficits, skeletal deformations, and psychosis. Because RSK2-inactivating mutations in humans lead to Coffin-Lowry syndrome, our results imply that alterations in GPCR signaling may account for some of its clinical manifestations.
An immunofluorescent demonstration of nuclear proteins
Creators: name: David, Lyle Anacletus
Publisher: name: University of British Columbia
Year: 2011

description: This thesis describes the development of an immunofluorescent technique and its application to a cytochemical study of the intracellular distribution of a basic protein component which satisfies several criteria used to identify histone. The technique was developed in three steps: 1. Production of Antibody The method of nuclear protein extraction, the preparation of the inoculum, the immunisation procedure and the species of antigen donor and recipient were all considered contributory of the successful production of antibody. 2. Analyses of Antigen and Antibody Electrophoretic and chromatographic techniques were employed to characterise the nuclear protein antigens. The antiserum was purified by immunological absorption and chromatography. The antigen-antibody responses were studied using electrophoretic and immunodiffusion techniques, both singly and in combination. 3. Application to Cell Preparations Fluorescent antibody provided a protein tracer with which to demonstrate the precise cytological location of analytically defined nuclear proteins. The antibody was produced in the chicken against basic protein from calf thymus nuclei. It was specific for nuclei and chromosomes but was neither organ nor species specific.
Il gioco e la morte. Forme della poesia a Venezia nel Cinquecento
Creators: name: Galavotti, Jacopo
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Lyrik
subject: poesia lirica
subject: Venezia
subject: Venedig
subject: Gabriele Fiamma
subject: Veronica Franco
subject: Luigi Groto
subject: Celio Magno
subject: 800 Literatur::850 Italienische, rumänische, rätoromanische Literaturen::851 Italienische Versdichtung

description: Der Band enthält vier Studien zu Dichter:innen, die während der zweiten Hälfte des 16. Jahrhunderts in der Region Venedig aktiv waren. Der erste Beitrag analysiert die Druck- und Manuskripttradition der Rime spirituali von Gabriele Fiamma und bietet eine kritische Textausgabe der Dichtungen. Der zweite Artikel untersucht die Bedeutung des “wilden” (selvaghesco) hapax, den Veronica Franco in einem Kapitel verwendet hat, das sie an Maffio Venier adressiert hat. Der dritte Aufsatz bietet ein Repertoire an Kunst-Stilmitteln aus dem lyrischen Werk Luigi Grotos sowie eine Analyse seiner Textproduktion vor dem Hintergrund der gängigen Definitionen von Manierismus. Der letzte Beitrag beschäftigt sich mit emphatischen rhetorischen Figuren und der Wortordnung innerhalb der Rime von Celio Magno, auch in Bezug auf der Konstruktion des Makrotextes. Durch diese Studien von vier exemplarischen Autor:innen an der Schnittstelle zwischen Stilistik, Philologie, Sprach- und Literaturgeschichte, stellt der Band einige relevante Aspekte der italienischen Lyrik des späten 16. Jahrhunderts heraus.
description: Il volume raccoglie quattro studi relativi ad altrettanti poeti di area veneziana attivi nella seconda metà del Cinquecento. Il primo analizza la tradizione a stampa e manoscritta delle Rime spirituali di Gabriele Fiamma, offrendo il testo critico delle rime disperse. Il secondo studio indaga il significato dell'hapax "selvaghesco" utilizzato da Veronica Franco in un capitolo indirizzato a Maffio Venier. Il terzo ampio saggio offre un repertorio delle figure artificiose utilizzate nella poesia lirica di Luigi Groto, e un’analisi della sua produzione alla luce delle definizioni correnti di Manierismo. L'ultimo contributo è un attraversamento delle figure dell'enfasi e dell'ordine delle parole nelle Rime di Celio Magno, anche in relazione alla costruzione del macrotesto. Attraverso lo studio di quattro autori esemplari, realizzato incrociando stilistica, filologia, storia della lingua e storia della letteratura, il libro mette a fuoco alcuni aspetti rilevanti della lirica del tardo Cinquecento.
Smooth electron waveguides in graphene
Creators: name: Hartmann, R. R.
name: Robinson, N. J.
name: Portnoi, M. E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present exact analytical solutions for the zero-energy modes of two-dimensional massless Dirac fermions fully confined within a smooth one-dimensional potential V(x)= - α/cosh(βx), which provides a good fit for potential profiles of existing top-gated graphene structures. We show that there is a threshold value of the characteristic potential strength α/β for which the first mode appears, in striking contrast to the non-relativistic case. A simple relationship between the characteristic strength and the number of modes within the potential is found. An experimental setup is proposed for the observation of these modes. The proposed geometry could be utilized in future graphene-based devices with high on/off current ratios.
description: 8 Pages including 4 figures, an appendix and two additional figures added, references updated
Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Gαq-coupled protein receptors
Creators: name: Compton-Toth, B.
name: Roth, B.L.
name: Bhatnagar, A.
name: Sheffler, D.J.
name: Kroeze, W.K.
Publisher: name: American Society for Biochemistry and Molecular Biology Inc.
Year: 2004

description: 5-Hydroxytryptamine 2A (5-HT2A) serotonin receptors are important for a variety of functions including vascular smooth muscle contraction, platelet aggregation, and the modulation of perception, cognition, and emotion. In a search for 5-HT2A receptor-interacting proteins, we discovered that caveolin-1 (Cav-1), a scaffolding protein enriched in caveolae, complexes with 5-HT2A receptors in a number of cell types including C6 glioma cells, transfected HEK-293 cells, and rat brain synaptic membrane preparations. To address the functional significance of this interaction, we performed RNA interference-mediated knockdown of Cav-1 in C6 glioma cells, a cell type that endogenously expresses both 5-HT2A receptors and Cav-1. We discovered that the in vitro knockdown of Cav-1 in C6 glioma cells nearly abolished 5-HT2A receptor-mediated signal transduction as measured by calcium flux assays. RNA interference-mediated knockdown of Cav-1 also greatly attenuated endogenous Gαq-coupled P2Y purinergic receptor-mediated signaling without altering the signaling of PAR-1 thrombin receptors. Cav-1 appeared to modulate 5-HT2A signaling by facilitating the interaction of 5-HT2A receptors with Gαq. These studies provide compelling evidence for a prominent role of Cav-1 in regulating the functional activity of not only 5-HT 2A serotonin receptors but also selected Gαq-coupled receptors.
COVID-19 Test Positivity Rate as a marker for hospital overload
Creators: name: Gaspari, Mauro
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2021
Subjects: INF/01 Informatica

description: The use of antigen tests for the diagnosis of COVID-19 in Italy has risen sharply in autumn 2020. Italian regions like Alto Adige, Veneto, Toscana, Lazio, Piemonte and Marche did a large use of these tests for screening and surveillance purposes or for implementing diagnosis protocols in addition to molecular tests. As a consequence of this situation the basic test positivity rate (TPR) definition (i.e. number of new positive cases divided by the number of molecular tests) used at the beginning of the outbreak has lost in accuracy. In this paper, we emphasize the enormous potential of TPR index as a tool for monitoring the COVID-19 pandemic, and we show that the peaks of this index are related to the peaks of patients admitted in hospitals and intensive care units, which occurred on average from 16 and 12 days later approximately, considering all the Italian regions in the first phase of the pandemic. To conduct the study we have defined a novel version of the TPR index which takes into account the number of tests done with respect to the opulation, the number of infected individuals, and the number of patients healed, integrating it with antigen tests. Unfortunately, this index given the lack of data concerning antigen tests, so far cannot be computed for most Italian regions. However, using a limited set of data on antigen tests which were made available in November 2020, we have shown that the TPR forecasting properties are preserved in the second phase. Without any shadow of doubt, we argue that the defined TPR index could be successfully used as a forecasting tool to monitor the impact of COVID-19 in the healthcare system, and that antigen tests data should be standardized soon. We conclude the paper, defining an extended version of the TPR index to be used if more omplete data on antigen tests will be made available, also including vaccinate people.
Tsallis statistics as a tool for studying interstellar turbulence
Creators: name: Esquivel, A.
name: Lazarian, A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We used magnetohydrodynamic (MHD) simulations of interstellar turbulence to study the probability distribution functions (PDFs) of increments of density, velocity, and magnetic field. We found that the PDFs are well described by a Tsallis distribution, following the same general trends found in solar wind and Electron MHD studies. We found that the PDFs of density are very different in subsonic and supersonic turbulence. In order to extend this work to ISM observations we studied maps of column density obtained from 3D MHD simulations. From the column density maps we found the parameters that fit to Tsallis distributions and demonstrated that these parameters vary with the sonic and Alfvén Mach numbers of turbulence. This opens avenues for using Tsallis distributions to study the dynamical and perhaps magnetic states of interstellar gas.
description: 8 pages, 5 figures, 1 table. Accepted for publication in the Astrophysical Journal
Forage Production and Utilization in Feeding Dairy Cattle
Creators: name: Hodgson, Ralph E.
Publisher: name: Unknown
Year: 1955
Subjects: Crop Production/Industries
Dairy Farming
Farm Management
Land Economics/Use
Production Economics
Productivity Analysis

description: Modern concepts of livestock production revolve around growing and efficiently using farm-produced forage. The place of forages in the farm management scheme, in good land use practices, and in land conservation is established beyond doubt. Forages grown on efficiently managed land can be made to yield large amounts of essential feed nutrients comparable to those of other crops and at lower costs. On the other hand, poorly managed forage crops can be low yielding and expensive feeds. Unfortunately, too much of the land in forages is not as productive of feed nutrients as it could be, and there is opportunity here for farmers to increase their livestock feed supply.
description: Paper presented at a Joint Symposium on Forage Utilization by Dairy Cattle at the Annual Meeting of the American Dairy Science Association, East Lansing, Mich., June 22, 1955.
Surface Plasmon Enhanced Photoconductance of Gold Nanoparticle Arrays with Incorporated Alkane Linkers
Creators: name: Mangold, M. A.
name: Weiss, C.
name: Calame, M.
name: Holleitner, A. W.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We report on a photoconductive gain effect in two-dimensional arrays of gold nanoparticles, in which alkane molecules are inserted. The nanoparticle arrays are formed by a self-assembly process from alkanethiol-coated gold nanoparticles, and subsequently they are patterned on a Si/SiO2 chip by a microcontact printing technique. We find that the photoconductance of the arrays is strongly enhanced at the frequency of the surface plasmon of the nanoparticles. We interpret the observation as a bolometric enhancement of the conductance of the nanoparticle arrays upon excitation of the surface plasmon resonance.
The association between gas and galaxies III: The Cross-correlation of Galaxies and Ly-alpha Absorbers at z ~ 1
Creators: name: Shone, Allen M.
name: Morris, Simon L.
name: Crighton, Neil H. M.
name: Wilman, Richard
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We have measured the 2D 2-point correlation function, Xi_AG, between low column density Ly-alpha absorbers and galaxies at a redshift z ~ 1. We measured Ly-alpha absorbers between redshifts z=0.68 to 1.51 over a total redshift path length of Delta z=1.08 from HST STIS E230M absorption spectra towards the quasars HE 1122-1648 (z=2.4) and PKS 1127-145 (z=1.187). The column density of the Ly-alpha absorbers ranged from 13.2< log(N_HI (cm^-2))<17.4, with a median column density of log(N_HI)=14.0 . A total of 193 galaxy redshifts within the surrounding 6.8' x 5.7' field of view of both quasars were identified in a R magnitude limited survey (21.5
description: 22 pages, 18 figures. Accepted for publication in MNRAS
A direct interaction of PSD-95 with 5-HT2A serotonin receptors regulates receptor trafficking and signal transduction
Creators: name: Xia, Z.
name: Gray, J.A.
name: Roth, B.L.
name: Compton-Toth, B.A.
Publisher: name: American Society for Biochemistry and Molecular Biology Inc.
Year: 2003

description: The serotonin (5-hydroxytryptamine) 2A receptor (5-HT2A) is an important G protein-coupled receptor (GPCR) that mediates the effects of hallucinogens and is the target of a number of commonly prescribed medications including atypical antipsychotics, antidepressants, and anxiolytics. The 5-HT2A receptor possesses a canonical Type I PDZ-binding domain (X-Ser/Thr-X-Φ) at the carboxyl terminus and has been predicted, but never demonstrated, to interact with PDZ domain-containing proteins. We discovered that PSD-95, a prototypic PDZ domain-containing protein, directly associates with the 5-HT2A receptor and regulates 5-HT2A receptor-mediated signaling and trafficking in HEK-293 cells. Co-immunoprecipitation studies revealed that the native 5-HT2A receptor, but not a mutant lacking the PDZ-binding domain, interacted directly with PSD-95. The association with PSD-95 enhanced 5-HT2A receptor-mediated signal transduction, a novel action of PSD-95 on GPCRs. The augmentation of 5-HT2A receptor signaling by PSD-95 was not accompanied by alteration in the kinetics of 5-HT2A receptor desensitization but was associated with the inhibition of agonist-induced 5-HT2A receptor internalization. Additional studies demonstrated that 5-HT2A receptor and PSD-95 were co-localized in clusters on the cell surface of HEK-293 cells. Taken together, the present work elucidates novel roles for PSD-95 in regulating the functional activity and intracellular trafficking of 5-HT2A receptors and possibly other GPCRs.
Beyond the Convict System: the Aged Poor and Institutionalisation in Colonial Tasmania
Creators: name: Piper, AKS
Publisher: name: University Of Tasmania
Year: 2023

description: Colonial Tasmania's aged poor were initially managed through incarceration in government institutions under strict discipline and supervision. Essentially regimented penal environments, they were founded as a means to isolate, seclude and control pauper emancipists who were perceived as a social contagion. The incipient charitable institution housed an undifferentiated pauper population in which all inmates were seen as undeserving. This thesis investigates the mechanisms by which one constituent, the aged poor, transcended its mid-century categorisation to join the, ranks of the deserving. At first the agencies which dealt with invalids were ad hoc and marked by incompetence. As administrators learnt from their mistakes and came to - better understand the scale of the problem confronting them, new approaches were implemented. These may be characterised as refined inmate classification, institutional specialisation, centralisation of administrative power, bureaucratic professionalism and medicalisation of institutions. These tools, along with other measures, particularly coerced labour, strict discipline, confinement, surveillance, regimentation and punishment were used increasingly to control the lives of pauper invalids. They were also the means which led to reformers fighting for progressive invalid management regimes. Invalids were not passive participants in these events. They resisted the control measures imposed upon them and they proved to be proficient adversaries in manipulating the charitable system to their advantage. Classification, specialisation and surveillance resulted in a greater understanding of the issues confronting invalids. As the middle class involved themselves directly with invalids, the significance of the issues which had alienated them waned. Increasingly they were perceived as a medical rather than a moral problem. Coupled with this there were many changes in the conditions of institutional life which by our modern standards we would judge as progress. While there continued, and continues, to be unsavoury aspects to the management of the aged poor, what differed in 1901 when compared to earlier periods was that a greater number of people were prepared to involve themselves in changing the system for the better. Part of this was the result of increased knowledge. Foucault has drawn our attention to the link between knowledge and power. While he has focused attention upon the use of this power to discipline and punish this thesis demonstrates that knowledge can also be used as a vehicle for progressive reform.
Analytic treatment of complete and incomplete geodesics in Taub-NUT space-times
Creators: name: Kagramanova, Valeria
name: Kunz, Jutta
name: Hackmann, Eva
name: Laemmerzahl, Claus
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present the complete set of analytical solutions of the geodesic equation in Taub-NUT space-times in terms of the Weierstrass elliptic function. We systematically study the underlying polynomials and characterize the motion of test particles by its zeros. Since the presence of the "Misner string" in the Taub-NUT metric has led to different interpretations, we consider these in terms of the geodesics of the space-time. In particular, we address the geodesic incompleteness at the horizons discussed by Misner and Taub, and the analytic extension of Miller, Kruskal and Godfrey, and compare with the Reissner-Nordström space-time.
description: 22 pages, 14 figures, accepted for publication in PRD
Constructing elliptic curves over finite fields with prescribed torsion
Creators: name: Sutherland, Andrew V.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11G05, 11G07 (Primary) 11-04, 14H10 (Secondary)

description: We present a method for constructing optimized equations for the modular curve X_1(N) using a local search algorithm on a suitably defined graph of birationally equivalent plane curves. We then apply these equations over a finite field F_q to efficiently generate elliptic curves with nontrivial N-torsion by searching for affine points on X_1(N)(F_q), and we give a fast method for generating curves with (or without) a point of order 4N using X_1(2N).
description: Corrected typos in the statement of Lemma 2, 17 pages
Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6
Creators: name: Kristiansen, K.
name: Weiner, D.M.
name: Kroeze, W.K.
name: Roth, B.L.
name: Shapiro, D.A.
Publisher: name: American Society for Biochemistry and Molecular Biology Inc.
Year: 2002

description: 5-Hydroxytryptamine 2A (5-HT2A) receptors are essential for the actions of serotonin (5-hydroxytryptamine (5-HT)) on physiological processes as diverse as vascular smooth muscle contraction, platelet aggregation, perception, and emotion. In this study, we investigated the molecular mechanism(s) by which 5-HT activates 5-HT2A receptors using a combination of approaches including site-directed mutagenesis, molecular modeling, and pharmacological analysis using the sensitive, cell-based functional assay R-SAT. Alanine-scanning mutagenesis of residues close to the intracellular end of H6 of the 5-HT2A receptor implicated glutamate Glu-318(6.30) in receptor activation, as also predicted by a newly constructed molecular model of the 5-HT2A receptor, which was based on the x-ray structure of bovine rhodopsin. Close examination of the molecular model suggested that Glu-318(6.30) could form a strong ionic interaction with Arg-173(3.50) of the highly conserved "(D/E)RY motif" located at the interface between the third transmembrane segment and the second intracellular loop (i2). A direct prediction of this hypothesis, that disrupting this ionic interaction by an E318(6.30)R mutation would lead to a highly constitutively active receptor with enhanced affinity for agonist, was confirmed using R-SAT. Taken together, these results predict that the disruption of a strong ionic interaction between transmembrane helices 3 and 6 of 5-HT2A receptors is essential for agonist-induced receptor activation and, as recently predicted by ourselves (B. L. Roth and D. A. Shapiro (2001) Expert Opin. Ther. Targets 5, 685-695) and others, that this may represent a general mechanism of activation for many, but not all, G-protein-coupled receptors.
title: The Planned Slovak Comprehensive Music Database
title: A Collaborative Knowledge Base of all Music Ever Made on the Territory of the Slovak Republic
titleType: Subtitle
Creators: name: Antal, Daniel
Publisher: name: Digital Music Observatory
Year: 2023

description: The idea of the `SKCMDb` is to create a public-private partnership that helps the small Slovak music businesses and individual artists' ensembles remain visible and competitive in the era of big data, machine learning recommenders, and generative AI.
The sulfur isotopic consequence of seawater sulfate distillation preserved in the Neoproterozoic Sete Lagoas post-glacial carbonate, eastern Brazil
Creators: name: Okubo, Juliana
name: Kaufman, Alan J.
name: Warren, Lucas V.
name: Evans, Michael N.
name: Marroquín, Selva
name: Varni, Michael A.
name: Misi, Aroldo
name: Bahniuk, Anelize M.
name: Xiao, Shuhai
Publisher: name: Geological Society of London
Year: 2022
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Fig. 12
Towards a consistent account of firm survival
Creators: name: Jones, CD
Publisher: name: University Of Tasmania
Year: 2023

description: This study commenced with an interest in the question; why do some firms survive for considerably longer periods of time when other apparently similar types of firms operating under apparently similar conditions do not? Considering this issue in the context of the Hobart pizza industry led to the initial discovery of a very interesting paradox; an increase in apparent competition over time was associated with increased firm survival. Thus, this study sought to explain why firms appear to gain a survival advantage in the face of apparent competition. A theory-building methodology from the critical realism paradigm was used to facilitate an explanation-based case study approach. The process of retroduction was used to develop a novel explanation of firm survival, incorporating a stratified reality in which mechanisms, events and experiences exist. Thus, the study sought to confirm or disconfirm the operation of a generative mechanism and describe the contingent conditions under which it operates and/or is suppressed. The study proceeded through two distinct phases. First, the history of the Hobart pizza industry (1975 to 2005) was recorded and its development was compared to three other independent market places in northern Tasmania and Victoria across the same (general) period of time. From this process, five specific areas of focus emerged through which the events related to an unobservable mechanism seemed explainable. Those areas were; non-harmful relations, environmental heterogeneity, the ability of firms to alter their environment, the presence of an invisible energy, and lastly, firm survival. From a review of the organizational studies and broader ecological literatures, an initial model of Transferred Demand emerged. Second, the empirical investigation of the proposed Transferred Demand model occurred in North Yorkshire (UK), covering the period 1975 to 2004. Strong support for the postulates suggests that the proposed model of Transferred Demand has empirical strength as a new and innovative explanation of firm survival. Importantly, during the second phase of the study the specific transfactual conditions related to the operation of Transferred Demand where determined. In summary, this study solved the initial contradiction of increased apparent competition occurring alongside increased firm survival by enlisting a range of broader ecological theories to redefine what competition actually is. An important opportunity for future research arising from this study is the need to better understand the positive and negative coactions occurring between franchised firms and independent firms during the process of franchisation.
Frequency dependence of dielectric anomaly around Neel temperature in bilayer manganite Pr(Sr0.1Ca0.9)2Mn2O7
Creators: name: Ghosh, Barnali
name: Bhattacharya, Dipten
name: Raychaudhuri, A. K.
name: Arumugam, S.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: A novel frequency dependence of anomaly in dielectric constant versus temperature plot, around the Neel temperature T_N (~150 K), has been observed in a single crystal of bilayer manganite Pr(Sr0.1Ca0.9)2Mn2O7. The anomaly in the permittivity (epsilon'||c) occurs at a temperature T_f which moves within a temperature window (delT_f) of ~40 K around T_N for a frequency range 50 kHz-5 MHz. The capacitive component Cp of the dielectric response exhibits a clear yet broad feature around T_N which establishes the intrinsic capacitive nature of the anomaly.
description: 15 pages with 4 figures; pdf only
Salvinorin A: A potent naturally occurring nonnitrogenous κ opioid selective agonist
Creators: name: Baner, K.
name: Steinberg, S.
name: Ernsberger, P.
name: Siebert, D.
name: Roth, B.L.
name: Rice, K.C.
name: Westkaemper, R.
name: Rothman, R.B.
Publisher: name: National Academy of Sciences
Year: 2002

description: Salvia divinorum, whose main active ingredient is the neoclerodane diterpene Salvinorin A, is a hallucinogenic plant in the mint family that has been used in traditional spiritual practices for its psychoactive properties by the Mazatecs of Oaxaca, Mexico. More recently, S. divinorum extracts and Salvinorin A have become more widely used in the U.S. as legal hallucinogens. We discovered that Salvinorin A potently and selectively inhibited 3H-bremazocine binding to cloned κ opioid receptors. Salvinorin A had no significant activity against a battery of 50 receptors, transporters, and ion channels and showed a distinctive profile compared with the prototypic hallucinogen lysergic acid diethylamide. Functional studies demonstrated that Salvinorin A is a potent κ opioid agonist at cloned κ opioid receptors expressed in human embryonic kidney-293 cells and at native κ opioid receptors expressed in guinea pig brain. Importantly, Salvinorin A had no actions at the 5-HT2A serotonin receptor, the principal molecular target responsible for the actions of classical hallucinogens. Salvinorin A thus represents, to our knowledge, the first naturally occurring nonnitrogenous opioid-receptor subtype-selective agonist. Because Salvinorin A is a psychotomimetic selective for κ opioid receptors, κ opioid-selective antagonists may represent novel psychotherapeutic compounds for diseases manifested by perceptual distortions (e.g., schizophrenia, dementia, and bipolar disorders). Additionally, these results suggest that κ opioid receptors play a prominent role in the modulation of human perception.
The Dynamin-dependent, Arrestin-independent Internalization of 5-Hydroxytryptamine 2A (5-HT2A) Serotonin Receptors Reveals Differential Sorting of Arrestins and 5-HT2A Receptors during Endocytosis
Creators: name: Benovic, J.L.
name: Woods, J.
name: Gray, J.A.
name: Bhatnagar, A.
name: Roth, B.L.
name: Willins, D.L.
Publisher: name: American Society for Biochemistry and Molecular Biology Inc.
Year: 2001

description: 5-Hydroxytryptamine 2A (5-HT2A) receptors, a major site of action of clozapine and other atypical antipsychotic medications, are, paradoxically, internalized in vitro and in vivo by antagonists and agonists. The mechanisms responsible for this paradoxical regulation of 5-HT2A receptors are unknown. In this study, the arrestin and dynamin dependences of agonist- and antagonist-mediated internalization were investigated in live cells using green fluorescent protein (GFP)-tagged 5-HT2A receptors (SR2-GFP). Preliminary experiments indicated that GFP tagging of 5-HT 2A receptors had no effect on either the binding affinities of several ligands or agonist efficacy. Likewise, both the native receptor and SR2-GFP were internalized via endosomes in vitro. Experiments with a dynamin dominant-negative mutant (dynamin K44A) demonstrated that both agonist- and antagonist-induced internalization were dynamin-dependent. By contrast, both the agonist- and antagonist-induced internalization of SR2-GFP were insensitive to three different arrestin (Arr) dominant-negative mutants (Arr-2 V53D, Arr-2-(319-418), and Arr-3-(284-409)). Interestingly, 5-HT2A receptor activation by agonists, but not antagonists, induced greater Arr-3 than Arr-2 translocation to the plasma membrane. Importantly, the agonist-induced internalization of 5-HT2A receptors was accompanied by differential sorting of Arr-2, Arr-3, and 5-HT2A receptors into distinct plasma membrane and intracellular compartments. The agonist-induced redistribution of Arr-2 and Arr-3 into intracellular vesicles and plasma membrane compartments distinct from those involved in 5-HT2A receptor internalization implies novel roles for Arr-2 and Arr-3 independent of 5-HT2A receptor internalization and desensitization.