cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification of mRNA isoform switching in breast cancer
Creators: name: Hoadley, Katherine
name: Parker, Joel
name: Perou, Charles
name: Zhao, Wei
Publisher: name: BioMed Central
Year: 2016

description: Abstract Background Alternative splicing provides a major mechanism to generate protein diversity. Increasing evidence suggests a link of dysregulation of splicing associated with cancer. While previous genomic-based studies demonstrated the expression of a handful of tumor-specific isoforms, genome-wide alterations in the balance between isoforms and cancer subtypes is understudied. Result We systematically analyzed the isoform-level expression patterns and isoform switching events of 819 breast tumor and normal samples assayed by mRNA-seq from TCGA project. On average, 2.2 isoforms per gene were detected and 67.5 % of detected genes (i.e. expressed) showed 1–2 isoforms only. While the majority of isoforms for a given gene were positively correlated with each other and the overall gene level, 470 pairs of isoforms displayed an inverse correlation suggesting a switching event. Most of the isoform switching events were associated with molecular subtypes, including a Basal-like-associated switching in CTNND1. 88 genes showed switching independent of subtypes, among which the isoform pattern of PRICKLE1 was associated with a large genomic signature of biological significance. Conclusion Our results reveal that the majority of genes do not undergo complex mRNA splicing within breast cancers, and that there is a general concordance in isoform and gene expression levels in breast tumors. We identified hundreds of isoform switching events across breast tumors, most of which were associated with differences in tumor subtypes. As exemplified by the detailed analysis of CTNND1 and PRICKLE1, these isoform switching events potentially provide new insights into the post-transcriptional regulatory mechanisms of tumor subtypes and cancer biology.
title: Wrong place, wrong time: Imaging and embryological features of congenital renal anomalies
Creators: name: Osman, Mahomed
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Education and training
subject: Developmental disease
subject: Congenital
subject: Normal variants
subject: Education
subject: Ultrasound
subject: Fluoroscopy
subject: CT
subject: Urinary Tract / Bladder
subject: Kidney
subject: Anatomy

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To understand the normal embryological development of the kidneys. To understand the development of congenital renal ectopia and fusion resulting from failures in embryological development. To be able to recognize and correctly diagnose renal fusion...
Pengaruh Kualitas Layanan dan Kepuasan Pelanggan Terhadap Loyalitas Pelanggan di Boncafe Pentacity Mall Balikpapan
Creators: name: Mei Dita Maharani, Iswati
Publisher: name: Zenodo
Year: 2024

description: Penelitian ini bertujuan mengetahui pengaruh Kualitas Pelayanan terhadap Kepuasan Pelanggan dan Loyalitas Pelanggan. Penelitian ini di laksanakan di Boncafe Pentacity Mall Balikpapan Pada Tahun 2024 yang Dimana peneliti berhadapan langsung dengan responden. Responden dalam penelitian ini merupakan pengunjung yang loyal sehingga berkunjung lebih dari satu kali, Jumlah responden dalam penelitian ini ditetapkan 50 responden dengan menggunakan teknik pengambilan sampel yang skala Likert untuk menilai variabel-variabel yang diteliti. Analisis data dilakukan melalui serangkaian uji statistik, termasuk uji validitas dan reliabilitas untuk memastikan keandalan instrumen, serta analisis koefisien determinasi, regresi linier berganda, uji t, dan uji F untuk menguji hipotesis penelitian.Hasil penelitian ini menunjukkan bahwa: Terdapat pengaruh positif langsung Kualitas Pelayanan terhadap Kepuasan. Terdapat Pengaruh positif langsung Kepuasan terhadap Loyalitas. Terdapat pengaruh positif langsung Kualitas Pelayanan terhadap Loyalitas. Terdapat pengaruh positif tidak langsung Kualitas Pelayanan berpengaruh terhadap Loyalitas.
Anisotropy of Heat Conduction in Fibre-Reinforced Composites
Creators: name: Grove, SM
Publisher: name: University of Plymouth
Year: 1985

description: Merged with duplicate record 10026.1/2749 on 27.03.2017 by CS (TIS)
description: Fibre-reinforced composites usually exhibit anisotropy of thermal as well as mechanical properties. For example, in a unidirectional carbon fibre-reinforced plastic of 60% volume fraction, the longitudinal thermal conductivity may be greater than that in the transverse direction by a factor of 50, and greater than that of the unreinforced polymer by more than two orders of magnitude. In order to evaluate the engineering applications of thermal anisotropy, this thesis concentrates on the development and validation of a generalised finite element model of heat conduction in an anisotropic medium. This uses a variational formulation of the anisotropic time-dependent heat conduction equation, and is implemented for two and threedimensional quadratic finite elements. The model may be used for the solution of problems having any combination of steady or time-dependent boundary conditions (fixed temperature, convection, radiation, heat flux and internal heat generation), as well as nonlinear properties. Anisotropy is specified by the components of the two or threedimensional thermal conductivity tensor; efficient representation of nonhomogeneous materials is achieved by the specification of properties at element integration points. Theoretical validation of the model is carried out by means of a number of mathematical solutions to orthotropic and anisotropic problems. Experimental validation is performed by comparison of calculations with measured steady-state surface temperatures on a cylindrical specimen of unidirectional carbon fibre-reinforced epoxy resin. The thermal property data for this exercise are obtained from measurements of principal thermal conductivities on absolute and comparative steady-state apparatus. The use of the finite element model in two industrial applications is briefly described. These concern thermal cycling during composite fabrication with reinforced thermoplastic tape, and an analysis of heat transfer in a composite propeller blade.
Trends in equity in use of maternal health services in urban and rural Bangladesh
Creators: name: Curtis, Sian
Publisher: name: BioMed Central
Year: 2016

description: Abstract Background Maternal healthcare utilization is a major determinant of maternal mortality. Bangladesh is experiencing a rapid pace of urbanization with all future growth in population expected to be in urban areas. Health care infrastructure is different in urban and rural areas thus warranting an examination of equity in use rates of maternal healthcare. This paper addresses whether the urban–rural and rich-poor gaps in use of selected maternal healthcare indicators have narrowed or widened over the last decade. The paper also explores changes in the service provider environment in urban and rural domains. Methods The 2001 and 2010 Bangladesh Maternal Mortality and Health Care Survey data were used to examine trends in use of antenatal care from medically trained providers and in deliveries taking place at health facilities. Separate wealth quintiles were constructed for urban and rural areas. The concentration index was calculated for urban and rural areas to measure equity in distribution of antenatal care (ANC) and facility deliveries across wealth quintiles in urban and rural domains. Results The gap in use of ANC provided by medically trained personnel narrowed in urban and rural areas between 2001 and 2010 while that in facility deliveries widened. The difference in use of ANC by the rich and the poor was not as pronounced as that in utilization of facilities for deliveries. Over the last decade, equity in utilization of health facilities for deliveries has improved at a faster rate in urban areas. Private sector has surpassed the public sector and appears to be the dominant provider of maternal healthcare in both domains with the share of NGOs increasing in urban areas. Conclusions The faster pace of improvement in equity in maternal healthcare utilization in urban areas is reflective of the changing service environment in urban and rural areas, among other factors.
The weak ideal property and topological dimension zero
Creators: name: Pasnicu, Cornel
name: Phillips, N. Christopher
Publisher: name: arXiv
Year: 2016
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 46L05

description: Following up on previous work, we prove a number of results for C*-algebras with the weak ideal property or topological dimension zero, and some results for C*-algebras with related properties. Some of the more important results include: The weak ideal property implies topological dimension zero. For a separable C*-algebra~A, topological dimension zero is equivalent to RR (O_2 \otimes A) = 0, to D \otimes A having the ideal property for some (or any) Kirchberg algebra~D, and to A being residually hereditarily in the class of all C*-algebras B such that O_{\infty} \otimes B contains a nonzero projection. Extending the known result for Z_2, the classes of C*-algebras with topological dimension zero, with the weak ideal property, and with residual (SP) are closed under crossed products by arbitrary actions of abelian 2-groups. If A and B are separable, one of them is exact, A has the ideal property, and B has the weak ideal property, then A \otimes_{min} B has the weak ideal property. If X is a totally disconnected locally compact Hausdorff space and A is a C_0 (X)-algebra all of whose fibers have one of the weak ideal property, topological dimension zero, residual (SP), or the combination of pure infiniteness and the ideal property, then A also has the corresponding property (for topological dimension zero, provided A is separable). Topological dimension zero, the weak ideal property, and the ideal property are all equivalent for a substantial class of separable C*-algebras including all separable locally AH algebras. The weak ideal property does not imply the ideal property for separable Z-stable C*-algebras. We give other related results, as well as counterexamples to several other statements one might hope for.
description: 33 pages. Version 3 changes: Minor changes, mainly more discussion of previous work. Two added counterexamples related to previous work on the ideal property
Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits
Creators: name: Magnuson, Terry
name: Raab, Jesse R
name: Spear, Camarie C
name: Runge, John S
Publisher: name: BioMed Central
Year: 2017

description: Abstract Background SWI/SNF is a large heterogeneous multi-subunit chromatin remodeling complex. It consists of multiple sets of mutually exclusive components. Understanding how loss of one sibling of a mutually exclusive pair affects the occupancy and function of the remaining complex is needed to understand how mutations in a particular subunit might affect tumor formation. Recently, we showed that the members of the ARID family of SWI/SNF subunits (ARID1A, ARID1B and ARID2) had complex transcriptional relationships including both antagonism and cooperativity. However, it remains unknown how loss of the catalytic subunit(s) affects the binding and genome-wide occupancy of the remainder complex and how changes in occupancy affect transcriptional output. Results We addressed this gap by depleting BRG1 and BRM, the two ATPase subunits in SWI/SNF, and characterizing the changes to chromatin occupancy of the remaining subunit and related this to transcription changes induced by loss of the ATPase subunits. We show that depletion of one subunit frequently leads to loss of the remaining subunit. This could cause either positive or negative changes in gene expression. At a subset of sites, the sibling subunit is either retained or gained. Additionally, we show genome-wide that BRG1 and BRM have both cooperative and antagonistic interactions with respect to transcription. Importantly, at genes where BRG1 and BRM antagonize one another we observe a nearly complete rescue of gene expression changes in the combined BRG/BRM double knockdown. Conclusion This series of experiments demonstrate that mutually exclusive SWI/SNF complexes have heterogeneous functional relationships and highlight the importance of considering the role of the remaining SWI/SNF complexes following loss or depletion of a single subunit.
Low-income households’ responses to residential dissatisfaction: a phenomenological approach
Creators: name: ghezelseflou, saeid
name: emami, ali
Publisher: name: figshare
Year: 2023
Subjects: Architectural design
Housing policy
Phenomenology

description: Residential dissatisfaction occurs due to a discrepancy between residents’ expectations and their residential environment. This phenomenon appears in a confrontation process, mostly in low-income families who cannot afford to relocate, calling for extracting their lived experiences. This study aimed to extract the consequences of residential dissatisfaction so that residents’ various coping strategies were narrated. This narrative was achieved through transcendental phenomenology and semi-structured interviews. The residents of Mehr housing scheme contributed to expressing the mentioned narrative through purposive sampling of Minudasht, Iran. Meanwhile, transcriptions were divided into three categories: revision of needs, change in the physical environment and relocation. The results included eight themes that residents showed to residential dissatisfaction. Residents’ strategies for dealing with residential dissatisfaction were also structured by an analytical framework encompassing individual/family, social, internal and external aspects. This article provides fresh insights into residents’ responses to residential dissatisfaction both in theory and practice.
title: A case study: The treatment of a solitary melanoma metastase of the frontal lobe using flattening filter free beams
Creators: name: Pham, Lucy
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Metastases
subject: VMAT and Tomotherapy
subject: Stereotactic radiotherapy
subject: Radiation therapy / Oncology
subject: MR
subject: CT
subject: Cone beam CT
subject: Head and neck

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: 1) Metastatic brain tumours are the most common intracranial neoplasm occurring in 8.5 to 9.6% of all adult cancer patients.[1] Studies have shown effective advance treatments of primary cancers such as lung, breast, rectal and melanoma have led to...
Density Jumps Near the Virial Radius of Galaxy Clusters
Creators: name: Patej, Anna
name: Loeb, Abraham
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Recent simulations have indicated that the dark matter halos of galaxy clusters should feature steep density jumps near the virial radius. Since the member galaxies are expected to follow similar collisionless dynamics as the dark matter, the galaxy density profile should show such a feature as well. We examine the potential of current datasets to test this prediction by selecting cluster members for a sample of 56 low-redshift (0.1
description: 11 pages, 8 figures
Unveiling a Rich System of Faint Dwarf Galaxies in the Next Generation Fornax Survey
Creators: name: Munoz, Roberto P.
name: Eigenthaler, Paul
name: Puzia, Thomas H.
name: Taylor, Matthew A.
name: Ordenes-Briceno, Yasna
name: Alamo-Martinez, Karla
name: Ribbeck, Karen X.
name: Angel, Simon
name: Capaccioli, Massimo
name: Cote, Patrick
name: Ferrarese, Laura
name: Galaz, Gaspar
name: Hempel, Maren
name: Hilker, Michael
name: Jordan, Andres
name: Lancon, Ariane
name: Mieske, Steffen
name: Paolillo, Maurizio
name: Richtler, Tom
name: Sanchez-Janssen, Ruben
name: Zhang, Hongxin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report the discovery of 158 previously undetected dwarf galaxies in the Fornax cluster central regions using a deep coadded $u, g$ and $i$-band image obtained with the DECam wide-field camera mounted on the 4-meter Blanco telescope at the Cerro Tololo Interamerican Observatory as part of the {\it Next Generation Fornax Survey} (NGFS). The new dwarf galaxies have quasi-exponential light profiles, effective radii $0.1\!\!75\%$ at luminosities brighter than $M_i\!\simeq\!-15.0$ mag to $0\%$ at luminosities fainter than $M_i\!\simeq\!-10.0$ mag. The two-point correlation function analysis of the NGFS dwarf sample shows an excess on length scales below $\sim\!100$ kpc, pointing to the clustering of dwarf galaxies in the Fornax cluster core.
description: 6 pages, 3 figures. Accepted for publication in The Astrophysical Journal Letters. Download the high-resolution version of the paper from the following link: https://www.dropbox.com/s/xb9vz8s29wlzjgf/ms.pdf?dl=0
title: Technique and early clinical outcomes for spinal and paraspinal tumours treated with stereotactic body radiotherapy
Creators: name: Finnigan, Renee
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Oncology
subject: Cone beam CT
subject: Radiation therapy / Oncology
subject: Cancer
subject: Radiotherapy techniques

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: Stereotactic body radiotherapy (SBRT) involves the precise delivery of highly conformal and image-guided hypofractionated external beam radiotherapy to an extra-cranial target. 1 ,2 SBRT is increasingly being applied in the management of benign and...
title: Systematischer Ansatz zur archivischen Überlieferungsbildung
Creators: name: Luschin, Martina
Year: 2023

description: Die Masterarbeit befasst sich mit der archivischen Überlieferungsbildung österreichsicher Kommunalarchive. Das Ziel ist es, ein Dokumentationsprofil auf Grundlage der bundesdeutschen Diskussion zur Konzeption kommunaler Überlieferungsbildung und der daraus resultierenden, von Irmgard Christa Becker erstellten „Arbeitshilfe zur Erstellung eines Dokumentationsprofils für Kommunalarchive“ für das Stadtarchiv in Baden bei Wien zu erarbeiten. Durch die Evaluierung dieses Prozesses sollen allgemeine Anforderungen österreichischer Kommunalarchive an das Konzept ermittelt werden. Es lässt sich feststellen, dass sich die Anforderungen österreichischer Kommunalarchive im Allgemeinen nicht von jenen aus dem bundesdeutschen Raum unterscheiden. Herausforderungen bei der Erstellung entstehen hauptsächlich durch das Fehlen vergleichbarer Profile im österreichischen, aber auch im bundesdeutschen Raum, sowie durch die generell geringe Beteiligung österreichischer Kommunalarchive an der Diskussion zur archivischen Überlieferungsbildung, welche unter anderem auf die allgemeine finanzielle und personelle Situation eines Großteils der österreichischen Kommunalarchive zurückzuführen ist.
description: The master’s thesis deals with the acquisition strategies of Austrian community archives. The aim is to develop a documentation profile for the community archive of Baden near Vienna based on guidelines created by Irmgard Christa Becker, which are predicated on the concept of acquisition strategies form the Bundeskonferenz der Kommunalarchive in Germany. The evaluation of this process aims to determine general requirements of Austrian community archives for the concept. It can be said that the requirements of Austrian community archives generally do not differ from those of German archives. Challenges in the creation arise mainly from the lack of comparable profiles in Austria, but also in Germany, as well as from the in general low participation of Austrian community archives in the discussion on acquisition and appraisal strategies, which among other things is due to the general financial and personnel situation of a large part of Austrian community archives.
title: Inter- and intra-fraction motion in stereotactic body radiotherapy for spinal and paraspinal tumours using cone beam computed tomography and positional correction in six degrees of freedom
Creators: name: Finnigan, Renee
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Image verification
subject: Image guided radiotherapy
subject: Cancer
subject: Radiation therapy / Oncology
subject: Cone beam CT
subject: Oncology

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: Stereotactic body radiotherapy (SBRT) for spinal and paraspinal tumours involves the delivery of high biological equivalent doses in a small number of fractions to targets in close proximity to the spinal cord or cauda equina. With high doses per...
title: Open biomedical image analysis toolbox in the clouds
Creators: name: Arzhaeva, Yulia
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Computer applications
subject: Image manipulation / Reconstruction
subject: Computer Applications-General
subject: Image registration
subject: Molecular, genomics and proteomics

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: The primary goal of this work is to provide improved access to biomedical image processing and analysis software packages developed by CSIRO to nationwide research communities via remotely accessible...
Dual targeting of CCR2 and CX3CR1 in an arterial injury model of vascular inflammation
Creators: name: Jerath, Maya R
name: Patel, Dhavalkumar D
name: Liu, Peng
name: Rojas, Mauricio
name: Fong, Alan M
Publisher: name: BioMed Central Ltd
Year: 2010

description: Abstract Objectives The chemokine receptors CCR2 and CX3CR1 are important in the development of coronary artery disease. The purpose of this study is to analyze the effect of a novel CCR2 inhibitor in conjunction with CX3CR1 deletion on vascular inflammation. Methods The novel CCR2 antagonist MRL-677 was characterized using an in vivo model of monocyte migration. To determine the relative roles of CCR2 and CX3CR1 in vascular remodeling, normal or CX3CR1 deficient mice were treated with MRL-677. After 14 days, the level of intimal hyperplasia in the artery was visualized by paraffin sectioning and histology of the hind limbs. Results MRL-677 is a CCR2 antagonist that is effective in blocking macrophage trafficking in a peritoneal thioglycollate model. Intimal hyperplasia resulting from vascular injury was also assessed in mice. Based on the whole-blood potency of MRL-677, sufficient drug levels were maintained for the entire 14 day experimental period to afford good coverage of mCCR2 with MRL-677. Blocking CCR2 with MRL-677 resulted in a 56% decrease in the vascular injury response (n = 9, p < 0.05) in normal animals. Mice in which both CCR2 and CX3CR1 pathways were targeted (CX3CR1 KO mice given MRL-677) had an 88% decrease in the injury response (n = 6, p = 0.009). Conclusion In this study we have shown that blocking CCR2 with a low molecular weight antagonist ameliorates the inflammatory response to vascular injury. The protective effect of CCR2 blockade is increased in the presence of CX3CR1 deficiency suggesting that CX3CR1 and CCR2 have non-redundant functions in the progression of vascular inflammation.
title: Head and neck paraganglioma: Analysis of growth rates by radiologic imaging
Creators: name: Wang, Jeffrey Tzu-Yu
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Cancer
subject: Statistics
subject: MR
subject: CT
subject: Oncology
subject: Head and neck
subject: Ear / Nose / Throat
subject: Neoplasia

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: To estimate the growth rate of a glomus vagale, and to investigate the systematic difference between computed tomography (CT) and magnetic resonance imaging (MRI) in delineating the greatest axial diametre of head and neck (H&N) paragangliomas....
title: Implementing a left-sided breast deep inspiration breath hold technique using ABC by Elekta. The POW experience
Creators: name: Ambat, Julius
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Radiotherapy techniques
subject: Image guided radiotherapy
subject: Radiation therapy / Oncology
subject: CT
subject: Oncology
subject: Breast

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: To implement a Deep Inspiration Breath-Hold (DIBH) technique at Radiation Oncology department of the Prince of Wales Hospital (POWH), Randwick, using the Active Breathing Coordinator (ABC) device by Elekta, for the treatment of left-sided Breast...
title: The dosimetric impact of a systematic cranial-caudal shift in applicator needle position for high dose rate brachytherapy treatment to the prostate
Creators: name: Artschan, Rebecca
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Radioprotection / Radiation dose
subject: Ultrasound
subject: Brachytherapy
subject: Cancer

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: The treatment of prostate cancer using high dose rate (HDR) brachytherapy allows steep dose gradients to be shaped around the target; enabling a high dose to be delivered to the target whilst sparing organs at risk. During applicator...
5'-Serial Analysis of Gene Expression studies reveal a transcriptomic switch during fruiting body development in Coprinopsis cinerea
Creators: name: Wilke, Sarah K
name: Pukkila, Patricia J
Publisher: name: BioMed Central Ltd
Year: 2013

description: Abstract: Background: The transition from the vegetative mycelium to the primordium during fruiting body development is the most complex and critical developmental event in the life cycle of many basidiomycete fungi. Understanding the molecular mechanisms underlying this process has long been a goal of research on basidiomycetes. Large scale assessment of the expressed transcriptomes of these developmental stages will facilitate the generation of a more comprehensive picture of the mushroom fruiting process. In this study, we coupled 5'-Serial Analysis of Gene Expression (5'-SAGE) to high-throughput pyrosequencing from 454 Life Sciences to analyze the transcriptomes and identify up-regulated genes among vegetative mycelium (Myc) and stage 1 primordium (S1-Pri) of Coprinopsis cinerea during fruiting body development. Results: We evaluated the expression of >3,000 genes in the two respective growth stages and discovered that almost one-third of these genes were preferentially expressed in either stage. This identified a significant turnover of the transcriptome during the course of fruiting body development. Additionally, we annotated more than 79,000 transcription start sites (TSSs) based on the transcriptomes of the mycelium and stage 1 primoridum stages. Patterns of enrichment based on gene annotations from the GO and KEGG databases indicated that various structural and functional protein families were uniquely employed in either stage and that during primordial growth, cellular metabolism is highly up-regulated. Various signaling pathways such as the cAMP-PKA, MAPK and TOR pathways were also identified as up-regulated, consistent with the model that sensing of nutrient levels and the environment are important in this developmental transition. More than 100 up-regulated genes were also found to be unique to mushroom forming basidiomycetes, highlighting the novelty of fruiting body development in the fungal kingdom. Conclusions: We implicated a wealth of new candidate genes important to early stages of mushroom fruiting development, though their precise molecular functions and biological roles are not yet fully known. This study serves to advance our understanding of the molecular mechanisms of fruiting body development in the model mushroom C. cinerea.
title: Positional coincidence testing of kV and MV isocentres for cranial stereotactic radiotherapy delivery using both cine-EPID image based software and film acquisition
Creators: name: Artschan, Rebecca
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Radiation physics
subject: Cone beam CT
subject: Image manipulation / Reconstruction
subject: Radiation therapy / Oncology
subject: Stereotactic radiotherapy
subject: Quality assurance
subject: Image guided radiotherapy
subject: Radiotherapy techniques

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: Spatial accuracy of 1 mm or better is required for safe delivery of cranial stereotactic radiosurgery(SRS) and stereotactic radiotherapy (SRT) [1]. Intrinsic to SRT/SRS commissioning is establishing a test to evaluate the positional coincidence of...
Engaging with research ethics in central francophone africa: reflections on a workshop about ancillary care
Creators: name: Rennie, Stuart
Publisher: name: BioMed Central Ltd
Year: 2012

description: AbstractResearch ethics is predominantly taught and practiced in Anglophone countries, particularly those in North America and Western Europe. Initiatives to build research ethics capacity in developing countries must attempt to avoid imposing foreign frameworks and engage with ethical issues in research that are locally relevant. This article describes the process and outcomes of a capacity-building workshop that took place in Kinshasa, Democratic Republic of Congo in the summer of 2011. Although the workshop focused on a specific ethical theme – the responsibilities of researchers to provide health-related care to their research participants – we argue that the structure of the workshop offers a useful method for engaging with research ethics in general, and the theme of ancillary care encourages a broad perspective on research ethics that is highly pertinent in low-income countries. The workshop follows an interactive, locally driven model that could be fruitfully replicated in similar settings.
title: Point spread dose kernel distortion by in-line and perpendicularly aligned magnetic fields typical of MRI-linacs
Creators: name: Gargett, Maegan
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Physics
subject: MR
subject: Computer applications
subject: Radiation physics
subject: MR physics
subject: Radiotherapy techniques

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: Conventional treatment planning systems (TPS) use convolution algorithms to compute dose through the superposition of TERMA with energy deposition kernels (scaled for density), for example using a “collapsed cone” technique. The purpose of this...
Spectro-photometric characterization of high proper motion sources from WISE
Creators: name: Beamín, J. C.
name: Ivanov, V. D.
name: Minniti, D.
name: Smart, R. L.
name: Muzic, K.
name: Mendez, R. A.
name: Beletsky, Y.
name: Bayo, A.
name: Gromadzki, M.
name: Kurtev, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The census of the solar neighborhood is almost complete for stars and becoming more complete in the brown dwarf regime. Spectroscopic, photometric and kinematic characterization of nearby objects helps us to understand the local mass function, the binary fraction, and provides new targets for sensitive planet searches. We aim to derive spectral types and spectro-photometric distances of a sample of new high proper motion sources found with the WISE satellite, and obtain parallaxes for those objects that fall within the area observed by the Vista Variables in the Vía Láctea survey (VVV). We used low resolution spectroscopy and template fitting to derive spectral types, multiwavelength photometry to characterize the companion candidates and obtain photometric distances. Multi-epoch imaging from the VVV survey was used to measure the parallaxes and proper motions for three sources. We confirm a new T2 brown dwarf within $\sim$15 pc. We derived optical spectral types for twenty four sources, mostly M dwarfs within 50 pc. We addressed the wide binary nature of sixteen objects found by the WISE mission and previously known high proper motion sources. Six of these are probably members of wide binaries, two of those are new, and present evidence against the physical binary nature of two candidate binary stars found in the literature, and eight that we selected as possible binary systems. We discuss a likely microlensing event produced by a nearby low mass star and a galaxy, that is to occur in the following five years.
description: 13 pages, 5 figures, 5 tables, accepted MNRAS
title: Challenges in RT treatment of a pregnant patient: fetus safety and RT plan optimisation
Creators: name: Siddiqi, Fahim
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Radioprotection / Radiation dose
subject: Head and neck
subject: CT-High Resolution
subject: Radiation therapy / Oncology
subject: Radiation safety
subject: Radiotherapy techniques

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: To address the challenges involved in the treatment of a 26 weeks pregnant patient with SCC of the Right...
Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research
Creators: name: Garland, Eric L
name: Howard, Matthew O.
Publisher: name: BioMed Central
Year: 2018

description: Abstract Contemporary advances in addiction neuroscience have paralleled increasing interest in the ancient mental training practice of mindfulness meditation as a potential therapy for addiction. In the past decade, mindfulness-based interventions (MBIs) have been studied as a treatment for an array addictive behaviors, including drinking, smoking, opioid misuse, and use of illicit substances like cocaine and heroin. This article reviews current research evaluating MBIs as a treatment for addiction, with a focus on findings pertaining to clinical outcomes and biobehavioral mechanisms. Studies indicate that MBIs reduce substance misuse and craving by modulating cognitive, affective, and psychophysiological processes integral to self-regulation and reward processing. This integrative review provides the basis for manifold recommendations regarding the next wave of research needed to firmly establish the efficacy of MBIs and elucidate the mechanistic pathways by which these therapies ameliorate addiction. Issues pertaining to MBI treatment optimization and sequencing, dissemination and implementation, dose–response relationships, and research rigor and reproducibility are discussed.
Numerical and Analytical Modelling of Transit Time Variations
Creators: name: Hadden, Sam
name: Lithwick, Yoram
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We develop and apply methods to extract planet masses and eccentricities from observed transit time variations (TTVs). First, we derive simple analytic expressions for the TTV that include the effects of both first- and second-order resonances. Second, we use N-body Markov chain Monte Carlo (MCMC) simulations, as well as the analytic formulae, to measure the masses and eccentricities of ten planets discovered by Kepler that have not previously been analyzed. Most of the ten planets have low densities. Using the analytic expressions to partially circumvent degeneracies, we measure small eccentricities of a few percent or less.
description: 19 pages, 18 figures, submitted to ApJ
C*-algebraic partial compact quantum groups
Creators: name: De Commer, Kenny
Publisher: name: arXiv
Year: 2015
Subjects: subject: Operator Algebras (math.OA)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics

description: In this paper, we introduce C*-algebraic partial compact quantum groups, which are quantizations of topological groupoids with discrete object set and compact morphism spaces. These C*-algebraic partial compact quantum groups are generalisations of Hayashi's compact face algebras to the case where the object set can be infinite. They form the C*-algebraic counterpart of an algebraic theory of partial compact quantum groups developed in an earlier paper by the author and T. Timmermann, the correspondence between which will be dealt with in a separate paper. As an interesting example to illustrate the theory, we show how the dynamical quantum SU(2) group, as studied by Etingof-Varchenko and Koelink-Rosengren, fits into this framework.
description: 31 pages
On Local Strong Solutions to the Cauchy Problem of Two-Dimensional Density-Dependent Magnetohydrodynamic Equations with Vacuum
Creators: name: Lv, Boqiang
name: Xu, Zhonghai
name: Zhong, Xin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: This paper concerns the Cauchy problem of the nonhomogeneous incompressible magnetohydrodynamic (MHD) equations on the whole two-dimensional (2D) space with vacuum as far field density. In particular, the initial density can have compact support. We prove that the 2D Cauchy problem of the nonhomogeneous incompressible MHD equations admits a unique local strong solution provided the initial density and the initial magnetic decay not too slow at infinity.
description: 22 pages. arXiv admin note: text overlap with arXiv:1306.4752 by other authors
title: Radiation dose in fluoroscopy guided transforaminal nerve root and epidural steroid injections
Creators: name: Sheldon, James
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Musculoskeletal spine
subject: Fluoroscopy
subject: Radiation effects
subject: Quality assurance

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: To establish the radiation dose to the patient during a fluoroscopy guided transforaminal nerve root or transforaminal epidural injection at our institution. Determine whether there was a difference in radiation dose between the two fluoroscopy...
Orbital Differential Imaging: A New High-Contrast Post-Processing Technique For Direct Imaging of Exoplanets
Creators: name: Males, Jared R.
name: Belikov, Ruslan
name: Bendek, Eduardo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Current post-processing techniques in high contrast imaging depend on some source of diversity between the exoplanet signal and the residual star light at that location. The two main techniques are angular differential imaging (ADI), which makes use of parallactic sky rotation to separate planet from star light, and spectral differential imaging (SDI), which makes use of differences in the spectrum of planet and star light and the wavelength dependence of the point spread function (PSF). Here we introduce our technique for exploiting another source of diversity: orbital motion. Given repeated observations of an exoplanetary system with sufficiently short orbital periods, the motion of the planets allows us to discriminate them from the PSF. In addition to using powerful PSF subtraction algorithms, such an observing strategy enables temporal filtering. Once an orbit is determined, the planet can be ``de-orbited'' to further increase the signal-to-noise ratio. We call this collection of techniques Orbital Differential Imaging (ODI). Here we present the motivation for this technique, present a noise model, and present results from simulations. We believe ODI will be an enabling technique for imaging Earth-like planets in the habitable zones of Sun-like stars with dedicated space missions.
description: 9 page, 5 figures. Presented at SPIE 2015 (9605-42). See other ACESat papers by Belikov, Bendek, and Thomas
Speciation of Mercury by Chromatography Coupled with Atomic Spectrometry
Creators: name: Armstrong, Helen Elisabeth Louise
Publisher: name: University of Plymouth
Year: 2000

description: A commercial GC-AFS instrument has been developed and optimised for the speciation of organomercury. This instrument couples a GC oven to a modified atomic fluorescence detector via a ceramic pyrolyser. Organomercury compounds in dichloromethane solvent were directly injected through a Programmable Temperature Vaporiser Injector onto a DBl Megabore column. Once separated, the compounds eluted from the column and were atomised in the pyrolyser then detected by AFS. The direct injection technique, ceramic pyrolysis design and argon purged detector have improved previous instrument designs by enhancing and maintaining sensitivity. The instrumental limit of detection was determined to be 0.25 pg Hg absolute. Methods were developed for the extraction of methylmercury from a variety of marine samples. The techniques were validated using mussel homogenate and dogfish liver (IAEA 142, SRM 8044 and DOLT-2) certified reference materials. An interlaboratory comparision exercise was participated in and a method was developed for the detemination of methylmercury in Fucus sea plant (IAEA 140). A concentration of 0.63 ± 0.006 ng g-1 was reported. The material is now certified at 0.626 +0.139 ng g-1. Of all the participating laboratories, this was the closest result to the certified value. The instrument and methods were also applied to soil and sediment samples. Once again validation was performed with a CRM sediment, IAEA 356. Although this material has been reported to give positive artifact formation when using a steam distillation sample preparation procedure, good agreement and no artifects were observed upon analysis. A further contaminated land, an uncontaminated soil and sediment sample were also studied. For all the samples studied by GC-AFS total mercury measurements were also made following an appropriate digestion procedure and CV-AFS. A gas chromatograph was also coupled with ICP-MS and HPLC was coupled to CV-AFS as comparative techniques. Both approaches were optimised and validated with CRM's. The GC-ICP-MS had the advantage of providing additional element information and confirmed the presence of methylmercury bromide in the final mussel homogenate extract. The HPLC approach found to be much less sensitive than the GC techniques and also suffered from vapour generation interferences. The PTV injector was considered for large volume injection and thermal desorption techniques. Injector breakdown problems were overcome by optimising the conditions and solid phase adsorbent for cold splitless injection. A recovery of 70% was achieved for a 50 ul large volume injection of methylmercury chloride in DCM. This technique indicated the possibility that LVI may in the future offer increased method sensitivity.
Complex field-induced states in Linarite PbCuSO$_4$(OH)$_2$ with a variety of high-order exotic SDW$_p$ states
Creators: name: Willenberg, B.
name: Schäpers, M.
name: Wolter, A. U. B.
name: Drechsler, S. -L.
name: Reehuis, M.
name: Büchner, B.
name: Studer, A. J.
name: Rule, K. C.
name: Ouladdiaf, B.
name: Süllow, S.
name: Nishimoto, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Low-temperature neutron diffraction and NMR studies of field-induced phases in linarite are presented for magnetic fields $H \parallel b$ axis. A two-step spin-flop transition is observed as well as a transition transforming a helical magnetic ground state into an unusual magnetic phase with sine-wave modulated moments $\parallel H$. An effective $\tilde{J}_1$-$\tilde{J}_2$ single-chain model with a magnetization-dependent frustration ratio $α_{\rm eff} = -\tilde{J}_2/\tilde{J}_1$ is proposed. The latter is governed by skew interchain couplings and shifted to the vicinity of the ferromagnetic critical point. It explains qualitatively the observation of a rich variety of exotic (for strongly correlated cuprate spin-1/2 Heisenberg systems) longitudinal collinear spin-density wave SDW$_p$ states ($9 \geq p \geq 2$).
title: Pathology of the facial nerve: A pictorial review
Creators: name: Kwan, Pei Fun
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2014
Subjects: subject: Head and neck
subject: Anatomy
subject: CT
subject: MR
subject: Contrast agent-intravenous
subject: Education
subject: Education and training
subject: Pathology

description: Aim Methods and materials Results Conclusion Personal information References
description: Aim: Introduction: Pathology affecting the facial nerve is often clinically devastating as the facial nerve provides motor innervation to the muscle of facial expression. Imaging plays a crucial role in the diagnosis of facial nerve...
title: Inklusion chronisch kranker Mitarbeitender durch interne Kommunikation angesichts der COVID-19 Pandemie
Creators: name: Haberl, Susanne
Year: 2023

description: Die vorliegenden Masterarbeit beschäftigt sich mit dem Thema wie sich die internen Kommunikationsmaßnahmen im Hinblick auf chronisch kranke Mitarbeitende anlässlich der COVID-19 Pandemie auf die Beziehungsqualität zwischen Mitarbeitenden und Organisation und somit auf die Offenlegungsrate der Erkrankungen am Arbeitsplatz ausgewirkt haben sowie ob diese folglich einen Einfluss auf die Inklusion der Betroffenen hat? Durchgeführt wurde eine quantitative Studie (N=212) mittels Online-Befragung von österreichischen Arbeitnehmenden mit mindestens einer chronischen Erkrankung und/oder Behinderung. Die Forschungsarbeit bringt dabei die transparente symmetrische Kommunikation mit dem Erkennen von Vorteilen einer Offenlegung von Gesundheitsinformation, dem offenen Umgang mit einer chronischen Erkrankung am Arbeitsplatz, der Qualität der Beziehung zwischen Arbeitnehmenden und Organisation (EOR) und dem Grad der Inklusion in Verbindung.
Bright vigorous winds as signposts of supermassive black hole birth
Creators: name: Fiacconi, Davide
name: Rossi, Elena M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The formation of supermassive black holes is still an outstanding question. In the quasi-star scenario, black hole seeds experience an initial super-Eddington growth, that in less than a million years may leave a $10^4-10^5$ M$_{\odot}$ black hole at the centre of a protogalaxy at $z \sim 20-10$. Super-Eddington accretion, however, may be accompanied by vigorous mass loss that can limit the amount of mass that reaches the black hole. In this paper, we critically assess the impact of radiative driven winds, launched from the surface of the massive envelopes from which the black hole accretes. Solving the full wind equations coupled with the hydrostatic structure of the envelope, we find mass outflows with rates between a few tens and $10^4$ M$_{\odot}$ yr$^{-1}$, mainly powered by advection luminosity within the outflow. We therefore confirm the claim by Dotan, Rossi & Shaviv (2011) that mass losses can severely affect the black hole seed early growth within a quasi-star. In particular, seeds with mass $>10^4$ M$_{\odot}$ can only form within mass reservoirs $ \gtrsim 10^7$ M$_{\odot}$, unless they are refilled at huge rates ($ \gtrsim 100$ M$_{\odot}$ yr$^{-1}$). This may imply that only very massive halos ($>10^9$ M$_{\odot}$) at those redshifts can harbour massive seeds. Contrary to previous claims, these winds are expected to be relatively bright ($10^{44}-10^{47}$ erg s$^{-1}$), blue ($T_{\rm eff} \sim 8000$ K) objects, that while eluding the Hubble Space Telescope, could be observed by the James Webb Space Telescope.
description: 15 pages, 8 figures, accepted for publication in MNRAS