cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Stakeholders‟ Perception and Preferences of Post-harvest Quality Traits of Tomato in Ghana
Creators: name: Osei, Michael K.
name: Danquah, Agyemang
name: Blay, Essie
name: Danquah, Eric
name: Adu-Dapaah, Hans
name: Osei, Michael K.
name: Danquah, Agyemang
name: Blay, Essie
name: Danquah, Eric
name: Adu-Dapaah, Hans
Publisher: name: Unknown
Year: 2018
Subjects: subject: Crop Production/Industries
subject: tomato
subject: post-harvest traits
subject: PRA
subject: FGD
subject: descriptive study

description: The high levels of tomato consumption coupled with wide production levels in Ghana make the crop economically viable. Food preferences vary among individuals and geographical locations. Traits to select during crop improvement therefore, depend on the target beneficiaries. Breeders sometimes fail to consider preferences of end users probably because they are oblivious of them. This study used Participatory Rural Appraisal (PRA) and surveys to identify preferences and perceptions of end users in tomato value chain, for making proper breeding choices according to the information collected. The strategy employed for this research was descriptive survey. The target population included tomato farmers, market players and consumers. A multi-stage sampling was used to select the study sample. More than half (57.3%) of the respondents had been involved in tomato production for over 10 years. Sixteen variables were discussed with each group. The first three principal components (PCs) with Eigen values greater than 1.0 together explained 100% of total variation in the data set. Scores for ranking popular vegetable and ranking causes for poor shelf life were not significantly associated with any of the components. The Focus Group Discussion (FGDs) also established that, seven main vegetable crops were cultivated and produced by the communities and ranked tomato as number one. Similarly, six important quality traits of tomato were mentioned by stakeholders as their favorite. Respondents showed extreme preferences for firmness and shelf life as the most important quality traits of tomato. Seventy-seven-point five percent (77.5%) of the consumers use tomatoes every day in their food preparation. The study revealed stakeholders‟ desire and plea for firmness and extended shelf life of tomato fruits in Ghana. Consequently, the survey validated the need to regulate tomato breeding goals to develop high yielding tomatoes with improved fruit quality and prolonged shelf life.
Additional file 1 of Determinants of acute kidney injury during high-power mechanical ventilation: secondary analysis from experimental data
Creators: name: Gattarello, Simone
name: Lombardo, Fabio
name: Romitti, Federica
name: D’Albo, Rosanna
name: Velati, Mara
name: Fratti, Isabella
name: Pozzi, Tommaso
name: Nicolardi, Rosmery
name: Fioccola, Antonio
name: Busana, Mattia
name: Collino, Francesca
name: Herrmann, Peter
name: Camporota, Luigi
name: Quintel, Michael
name: Moerer, Onnen
name: Saager, Leif
name: Meissner, Konrad
name: Gattinoni, Luciano
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: Additional file 1: The supplemental material reports further details on the methodology we used to carried out the experiment and the analysis, as well as further results.
GDI D2.1 First analysis of cost elements for the setup of 1+MG infrastructure
Creators: name: Rasmussen, Troels
name: Hooft, Rob
Publisher: name: Zenodo
Year: 2024
Subjects: GDI
European Genomic Data Infrastructure
1+MG
1+Million Genomes Initiative
B1MG
Organisational Costs

description: Long-term financial sustainability is vital for any data infrastructure – but it is particularly true for infrastructures like 1+MG that depend on the accumulation of data over time to function. To accommodate the sensitive nature of the data, the computing infrastructure needs to be made available to users in secure processing environments and there needs to be sufficient storage in place. Coordinating and aligning compute hardware infrastructure, the data and services across many stakeholders and countries is challenging. The infrastructure will need to be able to support a large number of different users, working in research, health care and innovation.

This deliverable provides the first step in building the financial underpinnings of this understanding: it defines the functional elements across the infrastructure with their independent functions in operating the infrastructure, and provides lists of cost items for each of these functions including how they scale with regard to the size of the infrastructure. Future work will focus on possible sources of financing that can be appealed to for the maintenance of each of these functions.
Thin-film based ultralow noise SQUID magnetometer
Creators: name: Schmelz, M.
name: Zakosarenko, V.
name: Chwala, A.
name: Schönau, T.
name: Stolz, R.
name: Anders, S.
name: Linzen, S.
name: Meyer, H. -G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report on the development of an ultralow noise thin-film based SQUID magnetometer. A niobium thin-film pickup coil is connected to the input coil of a SQUID current sensor. The low capacitance of the used sub-micrometer cross-type Josephson junctions enable superior noise performance of the device. Application scenarios e.g. in geophysics and ultra-low field magnetic resonance imaging are discussed.
description: 3 pages, 2 figures
Additional file 1 of Sacral neuromodulation for constipation and fecal incontinence in children and adolescents – study protocol of a prospective, randomized trial on the application of invasive vs. non-invasive technique
Creators: name: Besendörfer, Manuel
name: Kirchgatter, Annemarie
name: Carbon, Roman
name: Weiss, Christel
name: Müller, Hanna
name: Matzel, Klaus E.
name: Diez, Sonja
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Chemical Sciences not elsewhere classified
Science Policy

description: Supplementary Material 1.
Additional file 1: Figures S1–S12. of Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Creators: name: Sanfilippo, Piero
name: Jiayu Wen
name: Lai, Eric
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Figure S1. Correlation of gene expression measurements derived using either RNA-seq or 3′-seq of matched ovary or testis samples. Figure S2. Principal component analysis of 3′-seq and RNA-seq data. Figure S3. Distribution of reads and 3′ ends onto genomic features. Figure S4. Examples of a gene with diverse APA patterns. Figure S5. Rare events maintain a signature of bona fide 3′ ends. Figure S6. Un-scaled analysis of weighted 3′ UTR length. Figure S7. Additional examples of APA dynamics in cell lines. Figure S8. APA dynamics during embryogenesis. Figure S9. Nucleotide distribution around D. yakuba and D. virilis 3′ ends. Figure S10. Numbers of additional miRNA sites and example of deeply conserved targets. Figure S11. Nucleotide distribution around D. melanogaster 3′ ends subdivided by class. Figure S12. Comparison of structural forming potential of the proximal and distal PAS-polyA regions. (PDF 4462 kb)
title: Les outils numériques au service de la compréhension en lecture d’élèves à besoins éducatifs particuliers
title: Les outils numériques au service de la compréhension en lecture d’élèves à besoins éducatifs particuliers
titleType: AlternativeTitle
Creators: name: Bovard, Lisa
name: Aldaz, Andrés
Publisher: name: Unknown
Year: 0
Subjects: subject: élèves à besoins éducatifs particuliers
subject: compréhension de texte
subject: outils numériques

description: Le numérique a pris une grande place dans nos vies quotidiennes, que ce soit à la maison ou à l’école. Nous nous sommes donc demandés si ces outils numériques pouvaient également être utilisés au bénéfice des apprentissages de nos élèves, notamment ceux à besoins éducatifs particuliers. Nous avons par conséquent décidé de lier ce domaine avec la compréhension de texte en français. Nous nous sommes demandés quel impact pouvaient possiblement avoir des outils numériques, et s’ils pouvaient permettre à nos élèves à besoins éducatifs particuliers de mieux réussir cette tâche complexe qu’est la compréhension d’un texte. Notre recherche consiste en une étude de sept cas, comportant des élèves dyslexiques, dysphasique, dyspraxiques ou encore dysharmoniques psychotiques. Nous leurs avons proposé deux compréhensions de texte différentes, la première sans outil numérique, et la seconde avec diverses technologies que les élèves pouvaient choisir d’utiliser ou non. Ces outils sont les suivants : l’écoute du texte préenregistré par l’enseignant.e ou par une personne tierce, la dictée à l’ordinateur et la lecture sur l’écran. Certains élèves ont décidé d’utiliser seulement l’écoute, tandis que d’autres ont utilisé les trois outils proposés. Les résultats obtenus suite à cette recherche ont montré que la plupart de ces sept élèves ont mieux réussi la deuxième compréhension de texte, mais qu’il est cependant difficile d’évaluer dans quelle mesure l’outil numérique a contribué à cette amélioration des résultats. Après avoir effectué des interviews avec ces élèves, et d’avoir discuté de leur ressenti et de leurs impressions, il en est ressorti qu’ils ont eu plus de temps pour se concentrer sur les questions en utilisant les diverses technologies proposées, et qu’ils ont éprouvé une moins grande fatigue ainsi qu’un meilleur sentiment de réussite.
Karyological and molecular analysis of Leucanthemum (Compositae, Anthemideae) in Corsica
Creators: name: Oberprieler, Christoph
name: Schinhärl, Lena
name: Wagner, Florian
name: Hugot, Laetitia
name: Vogt, Robert
Publisher: name: Freie Universität Berlin
Year: 2019
Subjects: subject: AFLP fingerprinting
subject: Anthemideae
subject: Asteraceae
subject: chromosome numbers
subject: Compositae
subject: Corse
subject: Corsica
subject: cytology
subject: Leucanthemum
subject: morphology
subject: taxonomy
subject: 500 Naturwissenschaften und Mathematik::580 Pflanzen (Botanik)::580 Pflanzen (Botanik)

description: Karyological, flow-cytometric and molecular analyses indicate that the genus Leucanthemum Mill. (Compositae, Anthemideae) is represented in Corsica (Corse) by two species: the tetraploid L. ircutianum DC. and the hexaploid L. corsicum (Less.) DC. The indication of the occurrence of the diploid L. vulgare Lam. on the island and of a tetraploid chromosome number for L. corsicum, given in former treatments of the genus for Corsica, could not be corroborated. AFLP fingerprinting further suggests that the infraspecific taxonomy of L. corsicum with two subspecies (L. corsicum subsp. corsicum and subsp. fenzlii) and three forms (L. corsicum f. corsicum, f. pinnatifidum and f. eschenlohrianum), which is mainly based on differences in the degree of leaf dissection, is not backed by genetic discontinuities. Owing to the observed little variation in leaf dissection within populations in the wild and the constancy of these features under cultivation, we propose the rank of varieties to taxonomically acknowledge these different stages in the broad spectrum of leaf-dissection grades exhibited by L. corsicum. As a consequence, the two new combinations L. corsicum var. eschenlohrianum (Gamisans) Vogt, Hugot & Oberpr. and L. corsicum var. fenzlii (Gamisans) Vogt, Hugot & Oberpr. are proposed.
A non-planar two-loop three-point function beyond multiple polylogarithms
Creators: name: von Manteuffel, Andreas
name: Tancredi, Lorenzo
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the analytic calculation of a two-loop non-planar three-point function which contributes to the two-loop amplitudes for $t \bar{t}$ production and $γγ$ production in gluon fusion through a massive top-quark loop. All subtopology integrals can be written in terms of multiple polylogarithms over an irrational alphabet and we employ a new method for the integration of the differential equations which does not rely on the rationalization of the latter. The top topology integrals, instead, in spite of the absence of a massive three-particle cut, cannot be evaluated in terms of multiple polylogarithms and require the introduction of integrals over complete elliptic integrals and polylogarithms. We provide one-fold integral representations for the solutions and continue them analytically to all relevant regions of the phase space in terms of real function, extracting all imaginary parts explicitly. The numerical evaluation of our expressions becomes straightforward in this way.
description: 27 pages, 1 figure, 1 ancillary file
Case-crossover study for the association between increased hospital admissions for respiratory diseases and the increase in atmospheric PM2.5 and PM2.5-bound trace elements in Pretoria, South Africa
Creators: name: Howlett-Downing, Chantelle
name: Boman, Johan
name: Molnár, Peter
name: Shirinde, Joyce
name: Wichmann, Janine
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Outdoor PM2.5 was sampled in Pretoria, 18 April 2017 to 28 February 2020. A case-crossover epidemiology study was associated for increased PM2.5 and trace elements with increased hospital admissions for respiratory disorders (J00-J99). The results included a significant increase in hospital admissions, with total PM2.5 of 2.7% (95% CI: 0.6, 4.9) per 10 µg·m−3 increase. For the trace elements, Ca of 4.0% (95% CI: 1.4%−6.8%), Cl of 0.7% (95% CI: 0.0%−1.4%), Fe of 3.3% (95% CI: 0.5%−6.1%), K of 1.8% (95% CI: 0.2–3.5) and Si of 1.3% (95% CI: 0.1%−2.5%). When controlling for PM2.5, only Ca of 3.2% (95% CI: 0.3, 6.1) and within the 0–14 age group by 5.2% (95% CI: 1.5, 9.1). Controlling for a co-pollutant that is highly correlated with PM2.5 does reduce overestimation, but further studies should include deposition rates and parallel sampling analysis.
Effects of mechanical processing and annealing on optical coherence properties of Er$^{3+}$:LiNbO$_3$ powders
Creators: name: Lutz, Thomas
name: Veissier, Lucile
name: Thiel, Charles W.
name: Woodburn, Philip J. T.
name: Cone, Rufus L.
name: Barclay, Paul E.
name: Tittel, Wolfgang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Optical coherence lifetimes and decoherence processes in erbium-doped lithium niobate (Er$^{3+}$:LiNbO$_3$) crystalline powders are investigated for materials that underwent different mechanical and thermal treatments. Several complimentary methods are used to assess the coherence lifetimes for these highly scattering media. Direct intensity or heterodyne detection of two-pulse photon echo techniques was employed for samples with longer coherence lifetimes and larger signal strengths, while time-delayed optical free induction decays were found to work well for shorter coherence lifetimes and weaker signal strengths. Spectral hole burning techniques were also used to characterize samples with very rapid dephasing processes. The results on powders are compared to the properties of a bulk crystal, with observed differences explained by the random orientation of the particles in the powders combined with new decoherence mechanisms introduced by the powder fabrication. Modeling of the coherence decay shows that paramagnetic materials such as Er$^{3+}$:LiNbO$_3$ that have highly anisotropic interactions with an applied magnetic field can still exhibit long coherence lifetimes and relatively simple decay shapes even for a powder of randomly oriented particles. We find that coherence properties degrade rapidly from mechanical treatment when grinding powders from bulk samples, leading to the appearance of amorphous-like behavior and a broadening of up to three orders of magnitude for the homogeneous linewidth even when low-energy grinding methods are employed. Annealing at high temperatures can improve the properties in some samples, with homogeneous linewidths reduced to less than 10 kHz, approaching the bulk crystal linewidth of 3 kHz under the same experimental conditions.
description: 13 pages, 7 figures
Effective approach for taking into account interactions of quasiparticles from the low-temperature behavior of a deformed fermion-gas model
Creators: name: Algin, Abdullah
name: Arikan, Ali Serdar
Publisher: name: arXiv
Year: 2017
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A deformed fermion gas model aimed at taking into account thermal and electronic properties of quasiparticle systems is devised. The model is constructed by the fermionic Fibonacci oscillators whose spectrum is given by a generalized Fibonacci sequence. We first introduce some new properties concerning the Fibonacci calculus. We then investigate the low-temperature thermostatistical properties of the model, and derive many of the deformed thermostatistical functions such as the chemical potential and the entropy in terms of the model deformation parameters p and q. We specifically focus on the p,q-deformed Sommerfeld parameter for the heat capacity of the model, and its behavior is compared with those of both the free-electron Fermi theory and the experimental data for some materials. The results obtained in this study reveal that the present deformed fermion model leads to an effective approach accounting for interaction and compositeness of quasiparticles, which have remarkable implications in many technological applications such as in nanomaterials.
description: 33 pages, 6 figures, 1 table
title: Cellular structures – computational biology of the macula
Creators: name: Luthert, Philip J.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: The macula has evolved to offer detection of light over a very wide range of intensities and at exquisitely graded resolution whilst presumably optimising energy consumption as photoreceptors are intrinsically energy demanding and the system is ‘always on’. This is achieved through the[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
Carnet nº 4, commencé à Novorossiïsk (p. 82)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 14-6-1929
Escherichia coli isolates from meat and abattoirs environment in Egypt: molecular characterization and control by nanosilver particles
Creators: name: Mansour, Alaa M.
name: Nossair, Mohamed A.
name: Soliman, Faten S.
name: Tawfik, Rasha Gomaa
name: Elekhnawy, Engy
name: Al-Kuraishy, Hayder M.
name: Batiha, Gaber El-Saber
name: Mahmoud, Mohamed H.
name: Alexiou, Athanasios
name: Shawky, Michael M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Three hundred samples, including meat from the slaughtered carcass and water, air samples, and swabs from the floor, wall, and employees' hands, were collected from five municipal abattoirs spread across several Egyptian provinces. The Escherichia coli was isolated from floor swabs, meat, air, wall, hand, and water samples. Serotyping of the recovered isolates clarified the presence of various serotypes, including enterohemorrhagic serotypes (O111: H4, O128: H2, and O127: H6) and enterotoxigenic serotypes (O44: H18 and O125: H21). The isolates were resistant to cefotaxime (100%), amoxiclav (80%), then rifampin (66.7%). The stx1 gene, stx2 gene, eaeA gene, blaCMY2 gene and iss gene were detected in 10-80 % of the isolates. Nanosilver (AgNPs) showed that 12.5 ppm was the lowest concentration that prevented bacterial growth. It was observed that 12% of workers wore a clean white coat, only 24% washed their hands between activities during work, only 14% used soap for hand washing, and 42% utilized the same knife for meat and its offal.
title: Qu’est-ce qu’une « bonne collaboration » entre enseignant.es et parents ? :
title: Points de vue croisés et pratiques
titleType: Subtitle
title: Qu’est-ce qu’une « bonne collaboration » entre enseignant.es et parents ? :
titleType: AlternativeTitle
Creators: name: Salzmann, Elodie
name: Porchet, Maurane
Publisher: name: Unknown
Year: 0

description: De nos jours, la collaboration est un aspect important et qui doit être pris en compte lorsque nous sommes enseignant.es. Nous sommes amenés à collaborer avec les différents acteurs qui interviennent en classe, mais aussi avec ceux qui travaillent avec nos élèves en dehors de l’école. Actuellement, la collaboration est une composante importante autant au sein des établissements que dans la loi elle-même. L’école et ses responsables cherchent désormais à faire des parents des collaborateurs au sein de l’environnement scolaire de leur enfant et non plus de simples spectateurs. Au travers d’une enquête ethnographique, notre travail de mémoire professionnel aborde la question de la collaboration entre les familles et les enseignant.es. Plus précisément, nous nous sommes intéressées à ce qui, aux yeux des enseignant.es et des parents, correspond à une « bonne collaboration » entre parents et enseignant.es. Pour essayer de répondre à cette problématique, nous avons effectué plusieurs entretiens avec les parents de nos classes respectives de stage et avons également interviewé nos praticiennes formatrices. Ces entretiens nous ont permis de faire ressortir les différents points de vue de chacun sur la question de la collaboration et, de ce fait, les éléments phares qui nous ont aidés à la rédaction de notre travail de Bachelor. Afin d’étayer davantage notre travail, nous nous sommes également penchées sur les différents travaux des auteurs ayant effectué des recherches sur la collaboration entre les écoles et les familles. Bon nombre d’éléments sont ressortis de ces lectures et nous avons pu nous baser sur ces connaissances pour comprendre avec plus de recul et de précision toute l'ampleur et la complexité du sujet. Grâce à cela, nous avons pu construire des parallèles entre le vécu des sujets interrogés et les recherches bibliographiques que nous avons menées afin d’en faire émerger les points les plus pertinents.
title: Molecular microarchitecture of macula in health and AMD
Creators: name: Curcio, Christine A.
name: Kar, D.
name: Dacey, D.M.
name: Anderson, D.M.G.
name: Kotnala, A.
name: Schey, K.L.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background: In normal human macula, we investigated with comprehensive molecular and ultrastructural technologies an ecosystem that contributes to drusen lipids (PMID 30357337). Two features of high-risk drusen and their precursors in Bruch’s membrane implicate macular biology: enrichment in [for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
Additional file 1: of Expanding the spectrum of A20 haploinsufficiency in two Chinese families: cases report
Creators: name: Li, Guo-min
name: Liu, Hai-mei
name: Guan, Wan-zhen
name: Xu, Hong
name: Wu, Bing-bing
name: Sun, Li
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Genes associated with auto-inflammatory diseases. (DOCX 18Â kb)
Evidence for a White-light Flare on 10 September 1886
Creators: name: Vaquero, J. M.
name: Vázquez, M.
name: Almeida, J. Sánchez
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: We present evidence for the occurrence of a white-light flare on 10 September 1886. It represents the third of such rare events reported in the history of astronomy. The flare was mentioned by Valderrama (1886, L'Astronomie 5, 388). In this article we have used the original logbook of the observer, J. Valderrama y Aguilar, an amateur astronomer that lived in Madrid and Santa Cruz de Tenerife at that time.
description: 11 pages, 3 figures, accepted for publication in Solar Physics
title: Addressing choriocapillaris degeneration in AMD: cause, consequences, and potential therapies
Creators: name: Mullins, Robert F.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Both histological approaches and new imaging modalities reveal vascular loss in the choroid in AMD. Quantification of choroidal vascular lumen areas using a marker for viable endothelial cells shows loss of the choriocapillaris under intact RPE in early dry AMD, with more severe vascular degeneration[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
Ordonnance du conseil souverain, portant règlement touchant les salaires des baillis, lieutenans, hommes de fiefs, francs-allotiers, échevins & greffiers du bailliage de Tournay, Tournésis, Mortagne, Saint-Amand, etc., pour le relief des fiefs, adhéritances, etc.
Creators: name: Plouvain, Pierre-Antoine-Samuel-Joseph (1754-1832)
name: Six, Philippe-Josse-Auguste-Joseph (1732-1793)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: Justice royale
Organisation judiciaire
Rémunération
Office d'Ancien Régime

description: Source: http://nordnum.univ-lille.fr/ark:/72505/a0115224001360im5Ol/from/a011522400136ypxWl2
description: Coverage: Parlement de Flandre
description: issued: 27/05/1672
Applications of image-based high-throughput phenotypic profiling (HTPP) for hazard evaluation of environmental chemicals
Creators: name: Nyffeler, Johanna
name: Willis, Clinton
name: Culbreth, Megan
name: Brockway, Richard E.
name: Everett, Logan J.
name: Patlewicz, Grace
name: Shah, Imran
name: Chang, Daniel
name: Wambaugh, John
name: Friedman, Katie Paul
name: Harrill, Joshua A.
Publisher: name: F1000 Research Limited
Year: 2020

description: Poster presented at the ISMB 2020 conference (virtual).
title: Objective evaluation of human hearing
Creators: name: Picton, Terence
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Human hearing is generally evaluated using behavioral tests that assess a) hearing thresholds at different frequencies – the pure tone audiogram, and b) the recognition of spoken words at supra-threshold levels – speech audiometry. In certain cases, most importantly in newborn infants,[for full text, please go to the a.m. URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
title: Development of a genotyping assay for AMD: the EYE-RISK Consortium
Creators: name: de Breuk, Anita
name: Acar, I.E.
name: Kersten, E.
name: Schijvenaars, M.M.V.A.P.
name: Meester-Smoor, M.A.
name: Delcourt, C.
name: Klaver, C.C.W.
name: Monés, J.
name: Pauleikhoff, D.
name: Silva, R.
name: Fauser, S.
name: Hoyng, C.B.
name: Coenen, M.J.H.
name: den Hollander, A.I.
name: Consortium EYE-RISK
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Current genetic tests for age-related macular degeneration (AMD) are limited to a low number of genetic variants and vary widely in their risk assessment capacity. We aimed to develop an AMD genotyping assay that covers all currently known genetic variants and that can detect novel rare [for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
A TGAS/Gaia DR1 parallactic distance to the sigma Orionis cluster
Creators: name: Caballero, J. A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: With the new Tycho-Gaia Astrometric Solution, I derive a new parallactic distance to the young sigma Orionis open cluster, which is a cornerstone region for studying the formation and evolution of stars and substellar objects from tens of solar masses to a few Jupiter masses. I started with the list of the 46 brightest cluster stars of Caballero (2007). After identifying the 24 TGAS stars in the 30 arcmin-radius survey area and accounting for 11 FGKM-type dwarfs and giants in the fore- and background, I got a list of 13 cluster members and candidates with new parallaxes. Of them, I discarded five cluster member candidates with questionable features of youth and/or discordant parallaxes and proper motions, including a distant Herbig Ae/Be star, and proceeded with the remaining eight stars. The sigma Orionis mean heliocentric distance is d =360^{+44}_{-35} pc, which is consistent with a contemporaneous interferometric determination that concludes a two-decade dispute on the cluster distance. As a by-product, the re-classification of those five cluster member candidates, now interlopers, shows a manifest deficit of cluster stars between 1.2 and 2.1 Msol, which leaves the door open to new astrometric membership analyses with the next Gaia data releases.
description: Astronomische Nachrichten, accepted
title: Genetic Risk Score has added value over initial clinical grading stage in predicting disease progression in patients with non-advanced age-related macular degeneration – the Muenster Aging and Retina Study (MARS)
Creators: name: Heesterbeek, Thomas J.
name: de Jong, E.K.
name: Acar, I.E.
name: Groenewoud, J.M.M.
name: Liefers, B.
name: Sánchez, C.I.
name: Peto, T.
name: Hoyng, C.B.
name: Pauleikhoff, D.
name: Hense, H.W.
name: den Hollander, A.I.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Several prediction models for progression of age-related macular degeneration (AMD) have been developed, but the added value of using genetic information in those models in addition to clinical characteristics is ambiguous. In this study, we investigated the association between the genetic[for full text, please go to the a.m. URL]
description: 7th International Symposium on AMD: Age-related Macular Degeneration - Understanding Pathogenetic Mechanisms of Disease
THE IMPACT OF IMMERSIVE VIRTUAL REALITY ENVIRONMENTS ON LEARNING OUTCOMES AND ENGAGEMENT IN ONLINE HIGHER EDUCATION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Creators: name: LOBNA ELAMRANI
name: MOHAMED MOUGHIT
Publisher: name: Zenodo
Year: 2024
Subjects: Virtual Reality, Online Learning, Higher Education, Learning Outcomes, Student Engagement, Systematic Review, Meta-Analysis.

description: Abstract

The surge in student engagement in online learning during the COVID-19 pandemic has highlighted opportunities and challenges for higher education outside traditional classrooms. While online modalities offer flexibility, they often lack crucial elements for student engagement and hands-on learning. Immersive virtual reality (VR) aims to address this by digitally recreating physical learning environments through interactive 3D simulations. However, the evidence of VR's educational impact is limited. This study systematically reviews the effects of VR-enhanced online courses on cognitive and affective learning outcomes and student engagement among undergraduate and postgraduate learners compared to traditional online instruction. Seven academic journals and electronic literature sources were analyzed for experimental and quasi-experimental studies spanning from September 2013 to September 2023. Twenty studies involving 2,651 participants across disciplines, including health sciences, engineering, and teacher education, were included. Meta-analyses showed that VR significantly improved retention/recall test scores (SMD = 0.46, 95% CI 0.13 to 0.79, p = 0.006) and course assessments (SMD = 0.39, 95% CI 0.09 to 0.68, p = 0.01), indicating cognitive learning benefits. Qualitatively, VR enhanced student presence, collaboration, satisfaction, and motivation, particularly in learning procedural skills/processes. The study acknowledges a moderate risk of bias, mainly in randomization and blinding inadequacies. Despite limitations in study quality and generalizability, results suggest that VR positively impacts online higher education learners across cognitive and affective domains compared to traditional online instruction. While VR shows promise as an engagement tool, its effects may vary by domain. The study advocates for larger experimental studies directly comparing VR with online and blended modalities to further explore its potential in enhancing online learning experiences in higher education, positioning VR as a promising approach for educational improvement.
MOESM7 of Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile
Creators: name: Posukh, Olga
name: Maksimov, Daniil
name: Laktionov, Petr
name: Koryakov, Dmitry
name: Belyakin, Stepan
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Developmental Biology

description: Additional file 7: Figure S4. SuUR mutation has no effect of the expression levels of histone genes. Expression of the histone genes was measured using qPCR in SuUR mutant salivary glands and in wildÂ type control. No significant difference was detected using t test.
Primary data The relationship between serum CXCL8 and ET-1 expression levels and sepsis complicated with heart failure.xls
Creators: name: Wang, Kangning
Publisher: name: figshare
Year: 2022
Subjects: subject: 110708 Transplantation Immunology
subject: FOS: Clinical medicine

description: 探讨脓毒症并发心力衰竭与CXC趋化因子配体8（CXCL8）和内皮素-1（ET-1）表达水平的关系。
Nonequilibrium dynamics of probe filaments in actin-myosin networks
Creators: name: Gladrow, Jannes
name: Broedersz, Chase P.
name: Schmidt, Christoph F.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Active dynamic processes of cells are largely driven by the cytoskeleton, a complex and adaptable semiflexible polymer network, motorized by mechanoenzymes. Small dimensions, confined geome- tries and hierarchical structures make it challenging to probe dynamics and mechanical response of such networks. Embedded semiflexible probe polymers can serve as non-perturbing multi-scale probes to detect force distributions in active polymer networks. We show here that motor-induced forces transmitted to the probe polymers are reflected in non-equilibrium bending dynamics, which we analyze in terms of spatial eigenmodes of an elastic beam. We demonstrate how these active forces induce correlations among these mode amplitudes, which furthermore break time-reversal symmetry. This leads to a breaking of detailed balance in this mode space. We derive analytical predictions for the magnitude of resulting probability currents in mode space in the white-noise limit of motor activity. We relate the structure of these currents to the spatial profile of motor- induced forces along the probe polymers and provide a general relation for observable currents on two-dimensional hyperplanes.
description: 12 pages, 9 figures
Additional file 1: of An economic model of advance care planning in Australia: a cost-effective way to respect patient choice
Creators: name: Kim-Huong Nguyen
name: Sellars, Marcus
name: Agar, Meera
name: Kurrle, Sue
name: Kelly, Adele
name: Comans, Tracy
Publisher: name: figshare
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Data input and resources used in the economic model. (DOCX 70Â kb)
New butyrolactone and other metabolites from the bark of Endlicheria arenosa against of the phytopathogen Colletotrichum tamarilloi
Creators: name: Lady T. Albarracín
name: Wilman Delgado
name: Cuca, Luis Enrique
name: Ávila, Mónica C.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: In this work, screening of Lauraceae species for their antifungal activity against Collectotrichum tamarilloi was carried out and the ethanol extract derived from the bark of Endlicheria arenosa was found to be the best candidate. From the ethanolic extract of the bark of E. arenosa, the hexane and chloroform fractions were found to be active, from these five fatty acids were identified and two lactones were isolated. The most active fatty acid was the dodecanoic acid with a minimal inhibitory concentration (MIC) of 78.0 μM. The butyrolactone 3R,4R-licunolide A, it has not previously reported, and licunolide B show both the lowest MIC (55.3 μM). This is the first report of compounds of natural origin as growth inhibitors of C. tamarilloi.
MOESM6 of Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile
Creators: name: Posukh, Olga
name: Maksimov, Daniil
name: Laktionov, Petr
name: Koryakov, Dmitry
name: Belyakin, Stepan
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer

description: Additional file 6: Figure S3. Comparison of SUUR DamID profiles in Kc167 cells and in salivary gland. Data for Kc167 cells were taken from [5], profile in salivary glands was obtained in this study. The profiles are very consistent, although with some expectable cell type-specific differences (exemplified by black frame).
Fluctuations in quantum mechanics and field theories from a new version of semiclassical theory. II
Creators: name: Escobar-Ruiz, M. A.
name: Shuryak, E.
name: Turbiner, A. V.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This is the second paper on semiclassical approach based on the density matrix given by the Euclidean time path integral with fixed coinciding endpoints. The classical path, interpolating between this point and the classical vacuum, called "flucton", plus systematic one- and two-loop corrections, has been calculated in the first paper \cite{Escobar-Ruiz:2016aqv} for double-well potential and now extended for a number of quantum-mechanical problems (anharmonic oscillator, sine-Gordon potential). The method is based on systematic expansion in Feynman diagrams and thus can be extended to QFTs. We show that the loop expansion in QM reminds the leading log-approximations in QFT. In this sequel we present complete set of results obtained using this method in unified way. Alternatively, starting from the Schrödinger equation we derive a {\it generalized} Bloch equation which semiclassical-like, iterative solution generates the loop expansion. We re-derive two loop expansions for all three above potentials and now extend it to three loops, which has not yet been done via Feynman diagrams. All results for both methods are fully consistent with each other. Asymmetric (tilted) double-well potential (non-degenerate minima) is also studied using the second method.
Additional file 1 of Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition
Creators: name: Deben, Christophe
name: Boullosa, Laurie Freire
name: Fortes, Felicia Rodrigues
name: De La Hoz, Edgar Cardenas
name: Le Compte, Maxim
name: Seghers, Sofie
name: Peeters, Marc
name: Vanlanduit, Steve
name: Lin, Abraham
name: Dijkstra, Krijn K.
name: Van Schil, Paul
name: Hendriks, Jeroen M. H.
name: Prenen, Hans
name: Roeyen, Geert
name: Lardon, Filip
name: Smits, Evelien
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Supplementary Material 1.
Additional file 1: of Iron oxide nanoparticles induce reversible endothelial-to-mesenchymal transition in vascular endothelial cells at acutely non-cytotoxic concentrations
Creators: name: Wen, Tao
name: Du, Lifan
name: Chen, Bo
name: Yan, Doudou
name: Yang, Aiyun
name: Liu, Jian
name: Gu, Ning
name: Meng, Jie
name: Xu, Haiyan
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Figure S1. Representative morphology of low density of HUVECs treated with 300 and 600 μg/mL PSC-Fe2O3. Figure S2. PSC-Fe2O3 inhibited CD31 protein and gene expression, which was rescued by antioxidants. (A) Three replications of CD31 immunoblots. (B) Quantification of CD31 expression for HUVECs with different treatments. (C) Gene expression of CD31 for endothelial cell with different treatments. Data are mean ± SD, one-way ANOVA with LSD-t, ** p < 0.01. Figure S3. Representative of liver sections stained for mesenchymal markers α-SMA, and the endothelial markers CD31. Figure S4. Effects of bare Fe2O3 nanoparticles (bare-Fe2O3) on HUVECs. (A) TEM image for bare-Fe2O3. (B) Cell viability of HUVECs treated with different concentrations of bare-Fe2O3 for 24 h or 48 h. (C) Representative immunoblots of VE-Cadherin and α-SMA of HUVECs treated with 0, 10, 50 and 300 μg/mL of bare-Fe2O3 for 48 h. (D) Microscope observation of HUVEC cells treated with different concentrations of bare-Fe2O3 after Prussian blue staining. (DOCX 1010 kb)
title: Quellen der auditorisch evozierten Aktivität – EEG und MEG
Creators: name: Scherg, Michael
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Auditorisch evozierte Potentiale (AEP) bzw. magnetische Felder (AEF) werden z.B. durch kurze auditorische Stimuli wie Klicks oder kurze Tonepips ausgelöst. In audiologischen und neurologischen Untersuchungen werden sie nicht-invasiv als Spannungsdifferenz z.B. zwischen einer frontalen Elektrode[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 22. Jahrestagung der Deutschen Gesellschaft für Audiologie
On supersymmetric AdS6 solutions in 10 and 11 dimensions
Creators: name: Gutowski, J. B.
name: Papadopoulos, G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We prove a non-existence theorem for smooth, supersymmetric, warped AdS6 solutions with connected, compact without boundary internal space in D=11 and (massive) IIA supergravities. In IIB supergravity we show that if such AdS6 solutions exist, then the NSNS and RR 3-form fluxes must be linearly independent and certain spinor bi-linears must be appropriately restricted. Moreover we demonstrate that the internal space admits an so(3) action which leaves all the fields invariant and for smooth solutions the principal orbits must have co-dimension two. We also describe the topology and geometry of internal spaces that admit such a so(3) action and show that there are no solutions for which the internal space has topology F * S^2, where F is an oriented surface.
description: 26 pages, latex