cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Higher risk for chronic graft‐versus‐host disease (GvHD) in HLA‐G mismatched transplants following allogeneic hematopoietic stem cell transplantation : a retrospective study
Creators: name: Neuchel, Christine
name: Gowdavally, Sowmya
name: Tsamadou, Chrysanthi
name: Platzbecker, Uwe
name: Sala, Elisa
name: Wagner‐Drouet, Eva
name: Valerius, Thomas
name: Kröger, Nicolaus
name: Wulf, Gerald
name: Einsele, Hermann
name: Thurner, Lorenz
name: Schaefer‐Eckart, Kerstin
name: Freitag, Sebastian
name: Casper, Jochen
name: Dürholt, Mareike
name: Kaufmann, Martin
name: Hertenstein, Bernd
name: Klein, Stefan
name: Ringhoffer, Mark
name: Frank, Sandra
name: Amann, Elisa Maria
name: Rode, Immanuel
name: Schrezenmeier, Hubert
name: Mytilineos, Joannis
name: Fürst, Daniel
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: DDC 610 / Medicine & health
subject: Hematopoietic stem cell transplantation; Adverse effects
subject: Graft vs host disease
subject: HLA antigens
subject: Periphere Stammzellentransplantation
subject: Transplantat-Wirt-Reaktion
subject: HLA

description: Introduction Graft‐versus‐host disease (GvHD) is a major complication after allogeneic hematopoietic stem cell transplantation (allo‐HSCT) and is highly influenced by the degree of HLA matching between recipient and donor. The HLA‐class Ib molecule HLA‐G has been shown to promote tolerogenicity through its interaction with inhibitory receptors found on several immunocompetent cells. We hypothesized that in an allo‐HSCT setting, HLA‐G mismatches may negatively impact the HLA‐G‐mediated tolerogenicity either due to inefficient interaction with the inhibitory receptors of the transplanted immune cells or due to direct allorecognition of mismatched HLA‐G on host cells by the immune cells of the donor. Methods In order to explore this hypothesis, we investigated the impact of HLA‐G mismatching in 2.083 10/10 matched high resolution HLA‐typed allo‐HSCT transplants. Results We found that the risk of chronic GvHD was significantly higher in HLA‐G‐mismatched transplant cases as compared with the HLA‐G‐matched control group (HR: 1.46, 95%CI = 1.11–1.91, p = 0.006). Sub‐analysis of the mismatch vector revealed that this effect was only detectable in the GvH (HR: 1.89, 95%CI 1.39–2.57, p < 0.001) but not the HvG direction (HR: 1.01, 95%CI = 0.63–1.63, p = 0.967). In addition, the negative impact of HLA‐G mismatching on chronic GvHD was only significant in younger patients (<30y HR: 3.02, 95%CI = 1.25–7.28, p = 0.014; >29y HR: 1.28, 95%CI = 0.94–1.72, p = 0.113). Discussion Our results indicate that HLA‐G mismatches may contribute to the onset of chronic GvHD, especially in younger patients and should therefore be avoided when possible.
ИЗМЕНЕНИЕ АГРОКЛИМАТИЧЕСКОГО РАЙОНИРОВАНИЯ ТЕРРИТОРИИ СТАВРОПОЛЬСКОГО КРАЯ ДЛЯ ПОВЫШЕНИЯ ПРОДУКТИВНОСТИ АГРОЛАНДШАФТОВ
Creators: name: АНТОНОВ СЕРГЕЙ АНАТОЛЬЕВИЧ
Publisher: name: Оренбургский государственный аграрный университет (Оренбург)
Year: 2018

description: Цель исследования - разработка нового агроклиматического районирования территории Ставропольского края с учётом современных климатических условий для повышения продуктивности агроландшафтов. Проведена корректировка районирования на основе данных периода 1988-2017 гг. Согласно новому районированию в крае отмечается тенденция увеличения тепло- и влагообеспеченности вегетационного периода (рост суммы активных температур, снижение суровости зимы), что привело к изменению границ агроклиматических районов. Сократилась площадь очень засушливого и засушливого районов на 5 и 3% соответственно, увеличилась суммарная площадь неустойчивого влажного, умеренно влажного и влажного районов с 20510 км2 (31%) до 27787 км2 (42% площади края). Установлено, что по умеренно влажному району за период 1988-2017 гг. рост активных температур составил 336°С, и на 35 мм увеличилась сумма осадков вегетационного периода. Полученные результаты свидетельствуют о необходимости корректировки региональных систем земледелия на основе нового агроклиматического районирования Ставропольского края. Основным направлением корректировки является оптимизация структуры посевных площадей с расширением спектра возделываемых теплолюбивых культур (нут, могар, хлопчатник) и сокращением площадей чистых паров и зерновых культур путём их замены на более рентабельные.
Additional file 2 of Effects of Sjogren’s syndrome and high sugar diet on oral microbiome in patients with rampant caries: a clinical study
Creators: name: Tang, Yifei
name: Nie, Hua
name: Zhang, Yu
name: Wei, Yuan
name: Huang, Yequan
name: Zhuang, Yuan
name: Yang, Weidong
name: Zhu, Yanan
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Supplementary Material 2.
Uma Rede De Citações Para A Biblioteca Digital De Teses E Dissertações Da Universidade Federal Do Paraná
Creators: name: Silva Gonçalves, Aluísio Augusto
Publisher: name: Zenodo
Year: 2018
Subjects: Citation network
Digital repository
Record linkage
Bibliometrics

description: This work presents a tool for generating citation networks from documents stored in a digital repository, developed in order to discover the most influential works in the Electronic Theses and Dissertations Library of the Federal University of Paraná. Tools with similar objectives were evaluated, but they either operate with a curated, and therefore limited, corpus, or they do not support limiting queries to documents produced by authors affiliated with a given entity.

The evaluation of the tool on a subset of 7,275 documents from the UFPR Theses and Dissertations repository revealed a low percentage of bibliographic references internal to this repository. It is expected that tweaks to the parameters of the reference extraction and linking processes will reveal a more accurate picture of the scientific communication at the University.
Adiponectin, leptin and visfatin in hypoxia and its effect for weight loss in obesity
Creators: name: Rausch, Linda K.
name: Hofer, Maximilian
name: Pramsohler, Stephan
name: Kaser, Susanne
name: Ebenbichler, Christoph
name: Haacke, Sven
name: Gatterer, Hannes
name: Netzer, Nikolaus C.
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Visfatin
subject: DDC 610 / Medicine & health
subject: Hypoxia
subject: Obesity
subject: Weight loss
subject: Adiponectin
subject: Leptin
subject: Nicotinamide phosphoribosyltransferase
subject: Exercise
subject: Hypoxie
subject: Fettsucht
subject: Gewichtsabnahme
subject: Leptine
subject: Nicotinamid-Phosphoribosyltransferase

description: Rationale: Hypoxia induces leptin gene expression in human adipocytes via hypoxia-inducible factors (HIF-α/β). Under ambient moderate hypoxia, leptin in adipocytes is elevated for at least 14 days. Leptin is supposedly involved in the reduced food intake, increased utilization of fatty acids for energy production and possible weight loss observed at high altitudes. Literature on adiponectin and visfatin in high altitude is inconsistent with reports of elevated levels and non-elevated levels. Exercise in hypoxia studies in obese subjects have shown a significant weight loss after up to 3 weeks, but it is unclear if this effect holds up for longer time periods. Therefore, we aimed to investigate 32 obese subjects completing 52 exercise and rest sessions within 8 months at either moderate or sham hypoxia and to analyze leptin, adiponectin, and visfatin mRNA-expression at different time points of exposure. Methods: Abdominal subcutaneous fat biopsies were taken from 32 obese subjects before, after 3 months and after 8 months of intervention. Subjects were randomly divided into two groups and exercised at moderate intensity at two different study sites twice a week. The IG was exposed to normobaric hypoxia (FiO2: 14.0 ± 0.2%,) at exercise and at rest (FiO2: 12.0 ± 0.2%) and the CG to sham hypoxia. Quantitative real-time polymerase chain reaction (qPCR) was used in order to determine mRNA-levels of leptin, adiponectin, and visfatin. Results: No differences in leptin levels after 3 and 8 months compared to baseline and between groups were found. There was no significant difference regarding adiponectin or visfatin at any time point compared to baseline in the hypoxia group, but an increase after 3 months was seen in the control group at normoxia compared to the hypoxia group (adiponectin: p = 0.029 and visfatin: p = 0.014). Conclusion: In this first several months' duration randomized sham controlled hypoxia exercise and rest study with obese subjects, we found no time extended leptin mRNA-expression in subjects under hypoxia after 3 and 8 months compared to baseline levels. Moderate exercise in normoxia not in hypoxia leads to elevated adiponectin and visfatin levels after 3 months.
Un Método Geométrico para la Resolución de Ecuaciones Diferenciales del Tipo Cauchy-Euler sin Ecuación Característica
Creators: name: Adán Estudillo Anillo
Publisher: name: Zenodo
Year: 2025

description: Este trabajo presenta un enfoque geométrico innovador para la resolución de ecuaciones diferenciales del tipo Cauchy-Euler. A diferencia del método clásico, que se basa en la ecuación característica y la manipulación algebraica de raíces, el método aquí propuesto utiliza la construcción de un plano geométrico determinado por tres puntos clave. Esta técnica permite obtener la solución de manera directa, sin depender de artificios algebraicos.

El enfoque geométrico propuesto revela que el comportamiento logarítmico y lineal de la solución naturalmente como consecuencia de la estructura del plano, lo que aporta una interpretación más fundamental del problema. Además, este método introduce una constante adicional , que permite una mayor flexibilidad en la solución sin requerir la manipulación clásica de términos complejos.

Este trabajo destaca la simplicidad y elegancia del enfoque, que proporciona una alternativa más intuitiva y eficiente para la resolución de ecuaciones diferenciales homogéneas de segundo orden con coeficientes variables.
A conceptual approach to an open hospital information system
Creators: name: Kuhn, Klaus
name: Reichert, Manfred
name: Nathe, Michael
name: Beuter, Thomas
name: Heinlein, Christian
name: Dadam, Peter
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Distributed databases
subject: Information storage and retrieval systems. Hospitals
subject: Object-oriented databases
subject: Krankenhausinformationssystem

description: N/A
Additional file 1 of APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer
Creators: name: Yang, Shimin
name: Du, Jingxiao
name: Wang, Wei
name: Zhou, Dongmei
name: Xi, Xiaowei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health

description: Supplementary Material 1
sj-docx-1-rsm-10.1177_1321103X221128733 – Supplemental material for Self-regulation strategies and behaviors in the initial learning of the viola and violin with the support of software for real-time instrumental intonation assessment
Creators: name: López-Calatayud, Fernando
name: Tejada, Jesús
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-rsm-10.1177_1321103X221128733 for Self-regulation strategies and behaviors in the initial learning of the viola and violin with the support of software for real-time instrumental intonation assessment by Fernando López-Calatayud and Jesús Tejada in Research Studies in Music Education
Enhancing Type Safety in MPI with Rust: A Statically Verified Approach for RSMPI
Creators: name: Iqbal, Nafees
name: Brown, Jed
Publisher: name: Zenodo
Year: 2025

description: The Message Passing Interface (MPI) is a fundamental tool for building high-performance computing (HPC) applications, enabling efficient communication across distributed systems. Despite its widespread adoption, MPI’s low-level interface and lack of built-in type safety make it prone to runtime errors, undefined behavior, and debugging challenges, especially in large-scale applications. Rust, a modern systems programming language, offers a compelling solution with its strong type system, which enforces memory and type safety at compile time without compromising performance. This paper introduces a type-safe communication framework for MPI, built on the RSMPI library, to address the limitations of traditional MPI programming. At its core is the TypedCommunicator, an abstraction that enforces static type safety in point-to-point communication operations. By leveraging Rust’s Equivalence trait, our framework guarantees that only compatible types can participate in communication, catching mismatches either at compile time or through runtime validation. The framework supports both single-value and slice-based communication, providing an intuitive API for diverse data structures. Our implementation demonstrates that this approach eliminates common MPI errors, improves developer productivity, and maintains performance, adhering to Rust’s principle of zero-cost abstractions. This work lays the foundation for extending type safety to collective operations, advancing the robustness of parallel computing in Rust.
NG2-Glia transiently overcome their homeostatic network and contribute to wound closure after brain injury
Creators: name: Von Streitberg, Axel
name: Jäkel, Sarah
name: Eugenin Von Bernhardi, Jaime
name: Straube, Christoph
name: Buggenthin, Felix
name: Marr, Carsten
name: Dimou, Leda
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Proliferation
subject: Migration
subject: Polarization
subject: Stab wound injury
subject: In vivo two-photon imaging
subject: DDC 610 / Medicine & health
subject: Brain injuries
subject: Neuroglia
subject: Regeneration
subject: Schädel-Hirn-Trauma
subject: Gliazelle

description: In the adult brain, NG2-glia represent a cell population that responds to injury. To further investigate if, how and why NG2-glia are recruited to the injury site, we analyzed in detail the long-term reaction of NG2-glia after a lesion by time-lapse two-photon in vivo microscopy. Live imaging over several weeks of GFP-labeled NG2-glia in the stab wounded cerebral cortex revealed their fast and heterogeneous reaction, including proliferation, migration, polarization, hypertrophy, or a mixed response, while a small subset of cells remained unresponsive. At the peak of the reaction, 2–4 days after the injury, NG2-glia accumulated around and within the lesion core, overcoming the homeostatic control of their density, which normalized back to physiological conditions only 4 weeks after the insult. Genetic ablation of proliferating NG2-glia demonstrated that this accumulation contributed beneficially to wound closure. Thus, NG2-glia show a fast response to traumatic brain injury (TBI) and participate in tissue repair.
Micro- and macrovascular contributions to layer-dependent blood volume fMRI: a multi-modal, multi-species comparison
Creators: name: Huber, Laurentius
name: Goense, Jozien
name: Aneyrin Kennerley
name: Guidi, Maria
name: Trampel, Robert
name: Turner, Robert
name: Moeller, Harald E.
Publisher: name: F1000Research
Year: 2017

description: This study investigates cortical layer-dependent functional changes of cerebral blood volume (CBV) in humans, monkeys and rats at 7 T. Using multiple imaging modalities including vascular space occupancy (VASO), iron-oxide contrast agent based fMRI, and optical imaging spectroscopy, we investigated the contributions of pial macrovasculature and layer-specific microvasculature to CBV based fMRI signals. Based on the results presented here, we suggest that the pial macrovasculature can introduce constructive or destructive contributions to layer-dependent CBV responses. These contaminations manifest themselves differently, depending on the units (ml or %) used in the evaluation procedure.
The psychological and behavioral patterns of online psychological help-seekers before and during COVID-19 pandemic: a text mining-based longitudinal ecological study
Creators: name: Huang, Yinghui
name: Liu, Hui
name: Zhang, Lin
name: Li, Shen
name: Wang, Weijun
name: Ren, Zhihong
name: Zhou, Zongkui
name: Ma, Xueyao
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: online psychological help-seeking behavior
subject: online mental health service
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: COVID-19; Psychology
subject: Mental health services
subject: Telemedicine
subject: China
subject: Data mining
subject: COVID-19
subject: Telemedizin
subject: Notfallpsychiatrie
subject: Text Mining

description: Online mental health service (OMHS) platforms have contributed significantly to the public’s mental health during the COVID-19 pandemic in China. However, it remains unclear why the public used OMHS platforms for psychological help-seeking (PHS) behavior and how PHS behavior varied across different stages of the COVID-19 pandemic. Based on the ecological PHS behavior data from two OMHS platforms, we extracted population, psychological problems, and influential factors of PHS behavior by text mining and time series analysis methods. Seven top-ranked psychological problems (i.e., depression and anxiety, lack of interest, suicidal tendencies, social phobia, feelings of being worried and afraid, suffering, anger) and seven influential factors (i.e., interpersonal relationships, love, family, work, psychotherapy, personal characteristics, marriage) were found. The online PHS behaviors related to different psychological problems and influential factors remained a growing trend before 2020 and have been increasing significantly due to the COVID-19 outbreak. Four main stages were found during the pandemic according to the changes in the online PHS population: sharp growth, significant decline, slight rebound, and slow decline. This study identified large-scale, spontaneous PHS behaviors among the online public during the COVID-19 pandemic and the various psychological problems and influential factors that varied across different stages of the pandemic, suggesting that the government and health practitioners should adopt effective policies and strategies to prevent and intervene in mental health problems for the online public.
Information-centric networks in the IoT
Creators: name: Kammerer, Annalena
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: IoT
subject: Research Challenges
subject: ICN
subject: Data aware networking
subject: Content-centric Networking
subject: CCN
subject: DDC 004 / Data processing & computer science
subject: Internet of things
subject: Routing (Computer network management)
subject: Network architectures
subject: Information networks
subject: Internet der Dinge
subject: Routing

description: For several years, the number of physical devices connected to the Internet has steadily grown. Consequently, the produced and exchanged amount of data has increased, leading the current standard of the Internet to its limits. Therefore, a new approach said to solve this problem, has been introduced. Information-centric Networking (ICN) is an approach focused on evolving the Internet infrastructure away from a host-centric paradigm to a network architecture with the core principle of uniquely named data. By retrieving content using names, it is possible to identify named information independent from its location, application, storage and means of transportation. This way, the ICN approach aims to overcome the limitations of the current Internet standard, which, on the contrary, uses the location of the data to receive the content requested. This paper provides a general overview of ICN, its core principles, the most commonly proposed architecture concepts, the advantages and disadvantages of this new and revolutionary approach as well as current research challenges and opportunities.
Additional file 2 of APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer
Creators: name: Yang, Shimin
name: Du, Jingxiao
name: Wang, Wei
name: Zhou, Dongmei
name: Xi, Xiaowei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health

description: Supplementary Material 2
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 346 (48. Jg.), November 2018
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Zahnklinik zwischen Studium und Praxis
subject: Uni-Gesicht: Physik-Feuerwerk und Weihnachtsvorlesung
subject: Exzellent in der Batterieforschung
subject: Willkommen im Wintersemester
subject: DDC 050 / General serial publications
subject: Universities; Germany; Ulm
subject: Universities and colleges; Germany
subject: Universität Ulm

description: uni ulm intern - das Ulmer Universitätsmagazin mit Themen aus Forschung, Lehre und vom Campus
description: uni ulm intern, Das Ulmer Universitätsmagazin mit Themen aus Forschung, Lehre und vom Campus, Heft Nr. 346 (48. Jahrgang), November 2018
Supplemental Material - Using Behavioral Insights to Market a Workplace Safety Program: Evidence From a Multi-Armed Experiment
Creators: name: Juras, Randall
name: Gorman, Amy
name: Klerman, Jacob Alex
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental Material for Using Behavioral Insights to Market a Workplace Safety Program: Evidence From a Multi-Armed Experiment by Randall Juras, Amy Gorman and Jacob Alex Klerman in Evaluation Review
sj-docx-1-jht-10.1177_10963480221133778 – Supplemental material for Effects of Ethnocentrism on International Hospitality Brands: A Cross-Country Study of Starbucks
Creators: name: Cassia, Dr.Fabio
name: Magno, Dr.Francesca
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental material, sj-docx-1-jht-10.1177_10963480221133778 for Effects of Ethnocentrism on International Hospitality Brands: A Cross-Country Study of Starbucks by Dr.Fabio Cassia and Dr.Francesca Magno in Journal of Hospitality & Tourism Research
ศักยภาพภูมิปัญญาท้องถิ่นด้านอาหารพื้นบ้านของชุมชนแพรกหนามแดง อำเภออัมพวา จังหวัดสมุทรสงคราม
Creators: name: พจนีย์  บุญนา
name: ทรงสิริ  วิชิรานนท์
name: เปรมระพี  อุยมาวีรหิรัญ
Publisher: name: มหาวิทยาลัยเทคโนโลยีราชมงคลพระนคร
Year: 2018
Subjects: ภูมิปัญญาท้องถิ่น
อาหารพื้นบ้าน
ชุมชนแพรกหนามแดง

description: วารสารวิชาการและวิจัย มทร.พระนคร สาขามนุษยศาสตร์และสังคมศาสตร์, 3, 1, 63-74
title: Darstellung von Lesestrategien in Deutsch-als-Fremdsprache-Lehrwerken em Hauptkurs und Aspekte B1+
Creators: name: Horváthová, Veronika
Year: 2009

description: Ziel dieser Diplomarbeit ist neben einer theoretischen Auseinandersetzung mit dem Lesen als kognitiven Prozess die Frage, inwiefern die Umsetzung und Thematisierung von Lesestrategien in ausgewählten Deutsch-als-Fremdsprache-Lehrwerken gegeben ist. Im theoretischen Teil der Diplomarbeit wird das Problem einer exakten Definition von Leseprozess und -strategien wie auch der kognitionspsychologische Hintergrund der Leseforschung näher erläutert. Besonderes Augenmerk wird auf Möglichkeiten des expliziten und impliziten Trainings von Lesestrategien im DaF-Unterricht gelegt. Ausgehend von mehreren im theoretischen Teil ausgearbeiteten (erwähnten) Klassifizierungen der Lesestrategien wird anschließend eine selbständige Klassifizierung zusammengestellt. Die einzelnen Lesestrategien werden beschrieben und näher erläutert. Im empirischen Teil werden die Lehrwerke em Hauptkurs und Aspekte B1+, die Lesestrategien betreffend, analysiert. In diesen beiden Exempeln wird untersucht, ob und wie die gewählten Lehrwerke das Lesen mit Hilfe von Lesestrategien fördern. Obwohl die Konzeptionen der beiden Lehrwerke viele Ähnlichkeiten aufweisen, konnten vor allem in Bezug auf die Vermittlung von Lesestrategien Unterschiede festgestellt werden. Diese Unterschiede werden z.B. beim Grad an expliziter und impliziter Vermittlung von Lesestrategien und bei der Umsetzung ebendieser Lesestrategien transparent. Als Ergebnis der Lehrwerkanalysen kann festgehalten werden, dass die Lesestrategien einen Eingang in die Lehrpläne für den Fremdsprachenunterricht gefunden haben und deren verstärkte Beachtung sich in den neuen Lehrwerken im Rahmen einer systematischen Entwicklung der Lesekompetenz niederschlägt.
Automotive radar interference mitigation using a sparse sampling approach
Creators: name: Bechter, Jonathan
name: Roos, Fabian
name: Rahman, Mahfuzur
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: DDC 620 / Engineering & allied operations
subject: Signal processing
subject: Radar
subject: Radar; Interference
subject: Radarortung
subject: Signalverarbeitung
subject: Interferenz

description: The application of radar sensors for driver assistance systems and autonomous driving leads to an increasing probability of radar interferences. Those interferences degrade the detection capabilities and can cause sensor blindness. This paper uses a realistic road scenario to address the problems of a common countermeasure that simply removes interference-affected parts of time domain radar signals and thereby introduces a gap. The paper solves the problem with the application of a sparse sampling signal recovery algorithm that is also used for compressed sensing problems. It is shown that the signal recovery can clearly overcome the shortcomings of just removing interfered signal parts. In the end of the paper, the applicability of the used algorithm is verified with measured radar data.
Bi-allelic loss-of-function variants in KIF21A cause severe fetal akinesia with arthrogryposis multiplex
Creators: name: Falb, Ruth J
name: Müller, Amelie J
name: Klein, Wolfram
name: Grimmel, Mona
name: Grasshoff, Ute
name: Spranger, Stephanie
name: Stöbe, Petra
name: Gauck, Darja
name: Kuechler, Alma
name: Dikow, Nicola
name: Schwaibold, Eva M C
name: Schmidt, Christoph
name: Averdunk, Luisa
name: Buchert, Rebecca
name: Heinrich, Tilman
name: Prodan, Natalia
name: Park, Joohyun
name: Kehrer, Martin
name: Sturm, Marc
name: Kelemen, Olga
name: Hartmann, Silke
name: Horn, Denise
name: Emmerich, Dirk
name: Hirt, Nina
name: Neumann, Armin
name: Kristiansen, Glen
name: Gembruch, Ulrich
name: Haen, Susanne
name: Siebert, Reiner
name: Hentze, Sabine
name: Hoopmann, Markus
name: Ossowski, Stephan
name: Waldmüller, Stephan
name: Beck-Wödl, Stefanie
name: Gläser, Dieter
name: Tekesin, Ismail
name: Distelmaier, Felix
name: Riess, Olaf
name: Kagan, Karl-Oliver
name: Dufke, Andreas
name: Haack, Tobias B
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Nervous system diseases; Genetics
subject: Neuromuscular diseases; Genetics
subject: Neuropathologie
subject: Neuromuskuläre Krankheit
subject: Genetik

description: BackgroundFetal akinesia (FA) results in variable clinical presentations and has been associated with more than 166 different disease loci. However, the underlying molecular cause remains unclear in many individuals. We aimed to further define the set of genes involved.MethodsWe performed in-depth clinical characterisation and exome sequencing on a cohort of 23 FA index cases sharing arthrogryposis as a common feature.ResultsWe identified likely pathogenic or pathogenic variants in 12 different established disease genes explaining the disease phenotype in 13 index cases and report 12 novel variants. In the unsolved families, a search for recessive-type variants affecting the same gene was performed; and in five affected fetuses of two unrelated families, a homozygous loss-of-function variant in the kinesin family member 21A gene (KIF21A) was found.ConclusionOur study underlines the broad locus heterogeneity of FA with well-established and atypical genotype–phenotype associations. We describe KIF21A as a new factor implicated in the pathogenesis of severe neurogenic FA sequence with arthrogryposis of multiple joints, pulmonary hypoplasia and facial dysmorphisms. This hypothesis is further corroborated by a recent report on overlapping phenotypes observed in Kif21a null piglets.
sj-docx-5-joh-10.1177_27551938231176374 - Supplemental material for Have COVID-19 Stimulus Packages Mitigated the Negative Health Impacts of Pandemic-Related Job Losses? A Systematic Review of Global Evidence from the First Year of the Pandemic
Creators: name: McNamara, Courtney L.
name: Kotzias, Virginia
name: Bambra, Clare
name: Labonté, Ronald
name: Stuckler, David
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-docx-5-joh-10.1177_27551938231176374 for Have COVID-19 Stimulus Packages Mitigated the Negative Health Impacts of Pandemic-Related Job Losses? A Systematic Review of Global Evidence from the First Year of the Pandemic by Courtney L. McNamara, Virginia Kotzias, Clare Bambra, Ronald Labonté and David Stuckler in International Journal of Social Determinants of Health and Health Services
Additional file 1 of CircHAS2 activates CCNE2 to promote cell proliferation and sensitizes the response of colorectal cancer to anlotinib
Creators: name: Li, Haosheng
name: Feng, Haoran
name: Zhang, Tao
name: Wu, Junwei
name: Shen, Xiaonan
name: Xu, Shuiyu
name: Xu, Lianghui
name: Wang, Shaodong
name: Zhang, Yaqi
name: Jia, Wenqing
name: Ji, Xiaopin
name: Cheng, Xi
name: Zhao, Ren
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Supplementary Material 1
Cerebral immunohistochemical characterization of the H2S and the oxytocin systems in a porcine model of acute subdural hematoma
Creators: name: Denoix, Nicole
name: Merz, Tamara
name: Unmuth, Sarah
name: Hoffmann, Andrea
name: Nespoli, Ester
name: Scheuerle, Angelika
name: Huber-Lang, Markus
name: Gündel, Harald
name: Waller, Christiane
name: Radermacher, Peter
name: McCook, Oscar
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: albumin
subject: cystathionine-E-lyase
subject: barrier dysfunction
subject: DDC 610 / Medicine & health
subject: Brain injuries, Traumatic
subject: Complement activation
subject: Resuscitation
subject: Hydrogen sulfide
subject: Neurogenesis
subject: Tissues
subject: Receptors, Oxytocin
subject: Edema
subject: Vasopressins
subject: Schädel-Hirn-Trauma
subject: Hirnödem
subject: Wiederbelebung
subject: Komplement
subject: Vasopressin
subject: Serumalbumine
subject: Schwefelwasserstoff

description: The hydrogen sulfide (H2S) and the oxytocin/oxytocin receptor (OT/OTR) systems interact in trauma and are implicated in vascular protection and regulation of fluid homeostasis. Acute brain injury is associated with pressure-induced edema formation, blood brain barrier disruption, and neuro-inflammation. The similarities in brain anatomy: size, gyrencephalic organization, skull structure, may render the pig a highly relevant model for translational medicine. Cerebral biomarkers for pigs for pathophysiological changes and neuro-inflammation are limited. The current study aims to characterize the localization of OT/OTR and the endogenous H2S producing enzymes together with relevant neuro-inflammatory markers on available porcine brain tissue from an acute subdural hematoma (ASDH) model. In a recent pilot study, anesthetized pigs underwent ASDH by injection of 20 mL of autologous blood above the left parietal cortex and were resuscitated with neuro-intensive care measures. After 54 h of intensive care, the animals were sacrificed, the brain was removed and analyzed via immunohistochemistry. The endogenous H2S producing enzymes cystathionine-ɤ-lyase (CSE) and cystathionine-β-synthase (CBS), the OTR, and OT were localized in neurons, vasculature and parenchyma at the base of sulci, where pressure-induced injury leads to maximal stress in the gyrencephalic brain. The pathophysiological changes in response to brain injury in humans and pigs, we show here, are comparable. We additionally identified modulators of brain injury to further characterize the pathophysiology of ASDH and which may indicate future therapeutic approaches.
Effiziente Repräsentation von Vorlagen- und Instanzdaten in Prozess-Management-Systemen
Creators: name: Kreher, Ulrich
name: Reichert, Manfred
name: Rinderle-Ma, Stefanie
name: Dadam, Peter
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Implementierung von Prozess-Management-Systemen
subject: Process-aware information systems
subject: DDC 004 / Data processing & computer science
subject: ADEPT
subject: Management information systems
subject: Prozessinformationssystem
subject: Prozessmanagement

description: Ein Prozess-Management-System (PMS) muss umfangreiche Funktionen für die Steuerung, Verwaltung und Änderung von Geschäftsprozessen bieten. Um breit einsetzbar zu sein, ist eine performante Ausführung dieser Funktionen unverzichtbar, insbesondere bei großer Anzahl von Prozessinstanzen. In diesem Beitrag untersuchen wir einen wichtigen Performanzaspekt von PMS, die effiziente Speicherrepräsentation von Vorlagen- und Instanzdaten. Dazu setzen wir ein logisches Prozessmetamodell in programmiersprachenunabhängige technische Datenstrukturen um und zwar sowohl für Primär- als auch Sekundärspeicher. Wichtigstes Ziel ist die Minimierung des Primärspeicherbedarfs. Nur dadurch lässt sich zeitaufwendiges Ein- und Auslagern der zur Laufzeit benötigten Vorlagen- und Instanzdaten minimieren. Wir diskutieren grundlegende Realisierungsalternativen für die Speicherrepräsentation dieser Daten, und gehen darüber hinaus auf fortschrittliche Speicherkonzepte, wie die Clusterung von Prozessinstanzen, ein. Die vorgestellten Konzepte sind aktuell im ADEPT2-PMS umgesetzt.
Adaptive clustering for contour estimation of vehicles for high-resolution radar
Creators: name: Schlichenmaier, Johannes
name: Roos, Fabian
name: Kunert, Martin
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Laser radar
subject: Clustering algorithms
subject: Estimation
subject: Kernel
subject: Radar imaging
subject: Smoothing methods
subject: DDC 620 / Engineering & allied operations
subject: Cluster analysis
subject: Kernel functions
subject: Optical radar
subject: Cluster-Analyse
subject: Kernel
subject: Glättung
subject: Optischer Sensor

description: Future automotive radars will be able to achieve much higher range and angular resolution compared to currently used radar sensors. This enables functionalities like vehicle contour estimation to be used in advanced driver assistance systems, thus heavily increasing their performance. In this paper, the application of an adaptive algorithm on basis of k-nearest-neighbours examination for clustering radar data as precursor to estimation of width, length, and position of vehicles is presented and compared to a more basic algorithm. The influence of the parameters of this KNN-DBSCAN algorithm and its performance dependency on the used MIMO radar system is discussed.
Additional file 2 of CircHAS2 activates CCNE2 to promote cell proliferation and sensitizes the response of colorectal cancer to anlotinib
Creators: name: Li, Haosheng
name: Feng, Haoran
name: Zhang, Tao
name: Wu, Junwei
name: Shen, Xiaonan
name: Xu, Shuiyu
name: Xu, Lianghui
name: Wang, Shaodong
name: Zhang, Yaqi
name: Jia, Wenqing
name: Ji, Xiaopin
name: Cheng, Xi
name: Zhao, Ren
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Supplementary Material 2
Die rätselhafte Größe E. Was kann man sich unter Entropie vorstellen? - Erweiterte und korrigierte Auflage
Creators: name: Kreiner, Welf A.
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Chemische Verschiebung
subject: Chemisches Gleichgewicht
subject: Joule-Thomson-Effekt
subject: Komplexion
subject: Makrozustand
subject: Maxwell-Boltzmann-Verteilung
subject: Mikrozustand
subject: Planck
subject: Reversibler Vorgang
subject: Statistisches Gewicht
subject: Stirling-Näherung
subject: System
subject: Überströmversuch
subject: Unordnung
subject: DDC 530 / Physics
subject: Brownian motion process
subject: Statistical thermodynamics
subject: Fluid dynamics
subject: Maxwell-Boltzmann distribution law
subject: Entropy
subject: Clausius, R. (Rudolf) 1822-1888
subject: Boltzmann-Konstante
subject: Brownsche Bewegung
subject: Entropie
subject: Isotherme
subject: Thermodynamischer Zustand
subject: Statistische Thermodynamik
subject: Osmose
subject: Wahrscheinlichkeit
subject: Zustandsgleichung
subject: Schmelzenthalpie

description: Frei bewegliche Moleküle breiten sich spontan und gleichmäßig über den gesamten zur Verfügung stehenden Raum aus. Dies erklärt Boltzmann damit, dass es dafür wesentlich mehr Verteilungsmuster gibt als wenn sich die Moleküle auf einen kleinen Raum beschränkten. Eine bestimmte räumliche Anordnung von Molekülen heißt ein Mikrozustand. Eine Anzahl W von Mikrozuständen mit makroskopisch gleichen Eigenschaften bilden zusammen einen Makrozustand. W ist sein statistisches Gewicht. Auf Boltzmann geht es zurück, den Entropiebegriff mit dem Logarithmus des statistischen Gewichts zu verknüpfen. Die Entropie ist ein Maß für die Wahrscheinlichkeit eines Makrozustands. Clausius führte den Entropiebegriff als Zustandsfunktion in der Form dS= δQrev/T ein. Er beobachtete, dass die im Carnot-Prozess entlang einer Isotherme reversibel zugeführte Wärmemenge proportional ist zur absoluten Temperatur, also Qrev/T temperaturunabhängig ist. Auch diese Form des Entropiebegriffs kann mit einer spontanen Ausbreitung der Moleküle über ein stetig zunehmendes Volumen in Verbindung gebracht werden. Während nach der mikroskopischen Vorstellung (Verteilung einzelner, im Prinzip identifizierbarer Moleküle) die Entropie der Logarithmus eines statistischen Gewichts ist, also eine dimensionslose Größe, hat nach Clausius ΔS= Qrev/T die Dimension Arbeit/absolute Temperatur in den Einheiten Joule/Kelvin. Um nun sowohl in der Dimension wie auch im Zahlenwert übereinstimmende Ergebnisse für die Entropie zu erhalten, wird, nach Planck, das lnW mit der Boltzmann-Konstante k multipliziert, so dass man die Entropie zu S= k·lnW erhält. Dies ist ein Absolutwert für die Entropie in einem bestimmten Zustand. Thermodynamisch kann mit ΔS=Qrev/T jedoch nur eine Entropiedifferenz gemessen werden. Die spontane Entropiezunahme aufgrund der Molekülbewegung als Ursache einiger bekannter Effekte (Joule-Thomson-Effekt, Osmose u.a.) sowie ihre Bedeutung für chemische Reaktionen wird diskutiert.
Levothyroxine treatment of euthyroid children with autoimmune hashimoto thyroiditis: results of a multicenter, randomized, controlled trial
Creators: name: Dörr, Helmuth G.
name: Bettendorf, Markus
name: Binder, Gerhard
name: Karges, Beate
name: Kneppo, Carolin
name: Schmidt, Heinrich
name: Voss, Egbert
name: Wabitsch, Martin
name: Dötsch, Jörg
Publisher: name: Universität Ulm
Year: 2015
Subjects: subject: Levothyroxine treatment
subject: Euthyroid children
subject: Hashimoto thyroiditis
subject: DDC 610 / Medicine & health
subject: Hashimoto disease
subject: Child
subject: Thyroxine; Therapeutic use
subject: Hashimoto-Thyreoiditis
subject: Kind
subject: Thyroxin

description: Background: Levothyroxine (L-T4) treatment of euthyroid children with Hashimoto thyroiditis (HT) is a controversial issue. Patients and Methods: We conducted a prospective, randomized, controlled clinical trial. Out of 79 identified euthyroid patients, 59 started the study; 25 patients (21 female, 4 male; age: 11.8 ± 2.3 years) received L-T4 at a mean dose of 1.6 µg/kg (SD, 0.8) daily, and 34 (27 female, 7 male; age: 12.6 ± 1.2 years) were not treated. Patients developing subclinical hypothyroidism during follow-up (n = 13) were treated with L-T4 and removed from the observation group. As the main outcome measures, thyroid gland volume (determined by ultrasound) as well as serum levels of TSH, free T4, and antibodies against thyroid peroxidase and thyroglobulin were assessed every 6 months for 36 months. Results: At the start, the mean thyroid volume (standard deviation score, SDS) was 2.5 in the treatment group and 1.6 in the observation group. There was a constant decline in mean thyroid volume (SDS) from 2.13 (month 12) to 1.12 (month 30) in the treated group, with a delta thyroid volume of -1.01 SDS. In the observation group, the mean delta thyroid volume increased to +0.27 SDS. The change of the delta thyroid volume was statistically significantly different between both groups during the 12- and 30-month time points (p < 0.05). L-T4 had no effect on thyroid function and serum thyroid antibodies. Conclusions: L-T4 treatment can decrease the thyroid volume in euthyroid children with HT, but the effect is limited to a definite time period. © In Copyright http://rightsstatements.org/vocab/InC/1.0/
Additional file 3 of CircHAS2 activates CCNE2 to promote cell proliferation and sensitizes the response of colorectal cancer to anlotinib
Creators: name: Li, Haosheng
name: Feng, Haoran
name: Zhang, Tao
name: Wu, Junwei
name: Shen, Xiaonan
name: Xu, Shuiyu
name: Xu, Lianghui
name: Wang, Shaodong
name: Zhang, Yaqi
name: Jia, Wenqing
name: Ji, Xiaopin
name: Cheng, Xi
name: Zhao, Ren
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: Supplementary Material 3
The effect of non-personalised tips on the continued use of self-monitoring mHealth applications
Creators: name: Unnikrishnan, Vishnu
name: Schleicher, Miro
name: Shah, Yash
name: Jamaludeen, Noor
name: Pryss, Ruediger
name: Schobel, Johannes
name: Kraft, Robin
name: Schlee, Winfried
name: Spiliopoulou, Myra
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: tinnitus
subject: ecological momentary assessments
subject: physician feedback
subject: mHealth
subject: self-monitoring
subject: non-personalised tips
subject: DDC 610 / Medicine & health
subject: Tinnitus
subject: Telemedicine
subject: Ohrgeräusch
subject: Telemedizin

description: Chronic tinnitus, the perception of a phantom sound in the absence of corresponding stimulus, is a condition known to affect patients’ quality of life. Recent advances in mHealth have enabled patients to maintain a ‘disease journal’ of ecologically-valid momentary assessments, improving patients’ own awareness of their disease while also providing clinicians valuable data for research. In this study, we investigate the effect of non-personalised tips on patients’ perception of tinnitus, and on their continued use of the application. The data collected from the study involved three groups of patients that used the app for 16 weeks. Groups A & Y were exposed to feedback from the start of the study, while group B only received tips for the second half of the study. Groups A and Y were run by different supervisors and also differed in the number of hospital visits during the study. Users of Group A and B underwent assessment at baseline, mid-study, post-study and follow-up, while users of group Y were only assessed at baseline and post-study. It is seen that the users in group B use the app for longer, and also more often during the day. The answers of the users to the Ecological Momentary Assessments are seen to form clusters where the degree to which the tinnitus distress depends on tinnitus loudness varies. Additionally, cluster-level models were able to predict new unseen data with better accuracy than a single global model. This strengthens the argument that the discovered clusters really do reflect underlying patterns in disease expression.
MPEC 2024-W67 : 2024 WC1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 WC1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Long term outcome of functional independence and quality of life after traumatic SCI in Germany
Creators: name: Möller, Florian
name: Rupp, Rüdiger
name: Weidner, Norbert
name: Gutenbrunner, Christoph
name: Kalke, Yorck-Bernhard
name: Abel, Rainer F.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: DDC 610 / Medicine & health
subject: Spinal cord diseases
subject: Spinal cord injuries
subject: Rückenmarkskrankheit
subject: Rückenmarksverletzung
subject: Trauma

description: Abstract Study design Multicenter observational study. Objective To describe the long-term outcome of functional independence and quality of life (QoL) for individuals with traumatic and ischemic SCI beyond the first year after injury. Setting A multicenter study in Germany. Methods Participants of the European multicenter study about spinal cord injury (EMSCI) of three German SCI centers were included and followed over time by the German spinal cord injury cohort study (GerSCI). Individuals’ most recent spinal cord independence measure (SCIM) scores assessed by a clinician were followed up by a self-report (SCIM-SR) and correlated to selected items of the WHO short survey of quality of life (WHO-QoL-BREF). Results Data for 359 individuals were obtained. The average time passed the last clinical SCIM examination was 81.47 (SD 51.70) months. In total, 187 of the 359 received questionnaires contained a completely evaluable SCIM-SR. SCIM scores remained stable with the exception of reported management of bladder and bowel resulting in a slight decrease of SCIM-SR of −2.45 points (SD 16.81). SCIM-SR scores showed a significant correlation with the selected items of the WHO-QoL-BREF (p < 0.01) with moderate to strong influence. Conclusion SCIM score stability over time suggests a successful transfer of acquired independence skills obtained during primary rehabilitation into the community setting paralleled by positively related QoL measurements but bladder and bowel management may need special attention.