cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Two-Flavor Chiral Phase Transition in Lattice QCD with the Kogut-Susskind Quark Action
Creators: name: JLQCD Collaboration
name: Aoki, S.
name: Fukugita, M.
name: Hashimoto, S.
name: Ishizuka, N.
name: Iwasaki, Y.
name: Kanaya, K.
name: Kuramashi, Y.
name: Mino, H.
name: Okawa, M.
name: Ukawa, A.
name: Yoshié, T.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: A summary is presented of a scaling study of the finite-temperature chiral phase transition of two-flavor QCD with the Kogut-Susskind quark action based on simulations on $L^3\times4$ ($L$=8, 12 and 16) lattices at the quark mass of $m_q=0.075, 0.0375, 0.02$ and 0.01. We find a phase transition to be absent for $m_q\geq 0.02$, and also quite likely at $m_q=0.01$. The quark mass dependence of susceptibilities is consistent with a second-order transition at $m_q=0$. The exponents, however, deviate from the O(2) and O(4) values theoretically expected.
description: 3 pages, Latex(espcrc2,epsf), 3 ps figures, Poster presented at Lattice 97
Totally asymmetric exclusion process with site-wise dynamic disorder
Creators: name: Waclaw, Bartlomiej
name: Cholewa-Waclaw, Justyna
name: Greulich, Philip
Publisher: name: arXiv
Year: 2018
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Cellular Automata and Lattice Gases (nlin.CG)
subject: FOS: Physical sciences

description: We propose an extension of the totally asymmetric simple exclusion process (TASEP) in which particles hopping along a lattice can be blocked by obstacles that dynamically attach/detach from lattice sites. The model can be thought as TASEP with site-wise dynamic disorder. We consider two versions of defect dynamics: (i) defects can bind to any site, irrespective of particle occupation, (ii) defects only bind to sites which are not occupied by particles (particle-obstacle exclusion). In case (i) there is a symmetric, parabolic-like relationship between the current and particle density, as in the standard TASEP. Case (ii) leads to a skewed relationship for slow defect dynamics. We also show that the presence of defects induces particle clustering, despite the translation invariance of the system. For open boundaries the same three phases as for the standard TASEP are observed, albeit the position of phase boundaries is affected by the presence of obstacles. We develop a simple mean-field theory that captures the model's quantitative behaviour for periodic and open boundary conditions and yields good estimates for the current-density relationship, mean cluster sizes and phase boundaries. Lastly, we discuss an application of the model to the biological process of gene transcription.
description: submitted to J. Phys. A
Somatomedins/insulin-like growth factors, their receptors and binding proteins are present during mouse embryogenesis
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1987

description: Somatomedins/insulin-like growth factors (Sm/IGFs) are considered to have important roles in regulating fetal growth; however, because of limited quantities of tissue, few studies have been performed on their effects on embryonic growth. To assess a potential role for these factors, we evaluated mouse embryonic tissues for the presence of Sm/IGF and insulin receptors and Sm/IGF-binding proteins by chemical affinity labelling. In addition, we measured extractable Sm-C/IGF-I radioimmunoactivity in mouse embryonic tissues. Finally, we compared these data with those from the embryonal carcinoma cell line, PC13. All embryos from day 9 (3-4 somites) to day 12 (45 somites) possessed both Sm-C/IGF-I and IGF-II receptors in apparent greater abundance than insulin receptors. The visceral yolk sac appeared to have proportionally more insulin receptors than the corresponding embryonic tissue. Extracts from the embryos contained immunoreactive Sm-C/IGF-I and binding proteins of 30-45 X 10(3) Mr. PC13 cells possessed all three receptors and the apparent abundance of the insulin and IGF-II receptors was reduced after differentiation was induced with retinoic acid. PC13 cells released both immunoreactive Sm-C/IGF-I- and Sm-C/IGF-I-binding proteins into their medium. When differentiated, the binding proteins resembled the native ones extracted from the intact embryos. The presence of Sm/IGF activity, receptors and binding proteins in early embryogenesis suggests a role for these factors in embryonic growth. The PC13 cell line appears to only partially reflect normal development.
title: Using Interaction Logs for Creation and Maintenance of Trace Links
Creators: name: Hübner, Paul
name: Paech, Barbara
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: requirements
subject: trace link
subject: traceability
subject: maintenance
subject: precision
subject: recall
subject: ILCom
subject: commit
subject: log

description: Trace links between requirements and source code are beneficial for many software engineering tasks during development, e.g. maintenance, program comprehension and reengineering. It is necessary to keep trace links up-to-date for the continuous usage of the links during a project. Thus, maintenance of links along with changes in linked artefact is essential. Existing automatic trace link creation approaches are not capable to continuously provide and maintain links with high precision for direct usage by developers during a project. We therefore extended the commit linking by data captured from developers work. In our completely automatic approach ILCom, we use interaction logs recorded in an IDE while a developer is working on code files to implement a requirement. To assign the recorded interaction logs automatically to the requirement worked on, ILCom uses the issue IDs of requirements provided by developers in commit messages. This enables continuous link creation after each commit without manual effort from the developers. We evaluated our approach in several studies and showed that our ILCom approach is the first trace link creation and maintenance approach with very good precision and recall which does not require any manual work from the developers besides the common commitbased linking. In our presentation we introduce ILCom and the results of the evaluation studies. Further we sketch how maintenance of existing links along with changes in linked artefacts can be integrated in ILCom.
Patterns of N-CAM expression during myogenesis in Xenopus laevis
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1988

description: The neural cell adhesion molecule (N-CAM) is seen in the membrane of nerves and muscles from several vertebrate species. Using indirect immunofluorescence, we have examined the expression of this protein during embryonic and postembryonic myogenesis in the African clawed frog, Xenopus laevis. While good staining for N-CAM was seen in neuronal tissues at all stages examined, no staining of embryonic muscle was observed, including both mononucleated and polynucleated myoblasts. In contrast, limb muscles formed at metamorphosis showed strong expression of N-CAM. The developing limb muscles eventually lose their N-CAM, but will reexpress it dramatically when denervated. These observations suggest that myogenesis programs executed at different stages of development can display distinct patterns of N-CAM expression.
Getting the Most From Atmospheric Neutrinos
Creators: name: Pantaleone, J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Observations of atmospheric neutrinos by the SuperKamiokande collaboration have demonstrated large mixing of the muon-neutrino. However the present atmospheric neutrino data does not significantly constrain the associated mixing of the electron-neutrino, or the sign of the mass-squared difference. Here we identify the diagnostics for these quantities and they also test the theory of how matter affects neutrino oscillations. These diagnostics are a dip in the sub-GeV muon flux at a zenith angle of 110 degrees, a bump in the electron up-down asymmetry at multi-GeV energies and a bump in the muon-antimuon upward asymmetry.
description: 13 pages, 2 figures To be published in Physical Review Letters
title: Generische Negativszenarien in der Entwicklung kollaborativer cyber-physischer Systeme
Creators: name: Stenkova, Viktoria
name: Daun, Marian
name: Brings, Jennifer
name: Weyer, Thorsten
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: Negativszenario
subject: Misuse Case
subject: Sicherheit
subject: cyber-physisches System
subject: Kollaboration

description: Negativszenarien beschreiben beispielhafte Systemabläufe, die nicht gewünscht sind und somit zu Problemen und Gefahren bei der Benutzung des Systems führen können. Für kollaborative cyber-physischen Systeme ergeben sich neue Herausforderungen bezogen auf die Identifikation und Spezifikation von Negativszenarien. Im Zusammenspiel mit anderen Systemen formieren sich dynamische Systemverbünde. Durch die mannigfaltigen Möglichkeiten in der Zusammensetzung dieser Systemverbünde ergibt sich eine sehr große Anzahl zu berücksichtigender Negativszenarien. Generische Negativszenarien fassen mehrere Negativszenarien zusammen und gruppieren durch die Nutzung von Abstraktionsmechanismen gleichartige Instanzen und Nachrichten, um die Lesbarkeit zu erhöhen und den Umfang der Spezifikation zu verringern. Der vorgeschlagene Ansatz zur Spezifikation generischer Negativszenarien wurde bisher an einem industriellen Fallbeispiel evaluiert. Als Beispielsystem wurde eine kooperative adaptive Fahrgeschwindigkeitsregelung ausgewählt.
On the Use of Non-Contact Capacitive Sensors for the Assessment of Postural Hand Tremor of Individuals with Parkinson's Disease
Creators: name: Oliveira, Fábio Henrique M
name: Rabelo, Amanda G
name: Luiz, Luiza M D
name: Pereira, Adriano A
name: Vieira, Marcus F
name: Andrade, Adriano O
Publisher: name: Zenodo
Year: 2019
Subjects: Postural tremor
Parkinson's disease
Non-contact capacitive sensor
Frequency analysis

description: Parkinsonian tremor manifests in different types: rest, postural, and action tremors. The postural tremor occurs while a body part is held straight out from the body in a stable position against gravity. The Unified Parkinson’s Disease Rating Scale (UPDRS), which is a subjective assessment performed by the qualitative judgment of neurologists, is the clinical standard for parkinsonian tremor assessment. Despite the common use of subjective methods, inertial measurement unit (IMU) sensors are largely used in many studies as a motion capture system to objective assessment of tremors. However, this kind of sensor must be attached to the patient’s body, it limits the patient’s movements and requires specific techniques for correct positioning in the limb. In this sense, non-contact capacitive (NCC) sensors are an alternative proposed in this research to record the motor activity of the hand and wrist during a pose against gravity. In order to assess the postural tremor and evaluate this novel sensing technology, data from ten subjects, five with Parkinson’s disease (PD) and five neurologically healthy (H) matched in age and sex, were collected. We analyzed the instantaneous mean frequency (IMNF) of the signals from NCC and gyroscope sensors for both groups. The selected descriptive statistical variables allowed discrimination (p < 0.05) among subjects from H and PD groups while using the gyroscope or the NCC sensor. The obtained results indicate that the NCC sensor can measure the postural hand tremor, and also that frequency features extracted from the collected signals can be used to discriminate subjects from both groups.
Teratogens and craniofacial malformations: relationships to cell death
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1988

description: Environmental agents including ethanol, 13-cis retinoic acid (RA, Accutane), the antimetabolite methotrexate, periods of hypoxia, ionizing radiation or hyperthermic stress, when administered acutely to pregnant experimental animals, induce stage-dependent craniofacial malformations comparable to those in corresponding human teratogen syndromes. Acute treatment regimens have allowed analysis of cell populations initially affected and subsequent dysmorphogenetic sequences as well as speculation relative to mechanisms of teratogenesis. In rodent models, ethanol and RA appear to affect similar cell populations and comparable malformations can be induced by both agents. When administered during gastrulation they cause a major insult to the anterior neural plate which results in characteristic ocular, brain and facial malformations comparable to those seen in the fetal alcohol syndrome. Exposure to these drugs at a time just prior to and during neural crest cell migration into the craniofacial and cervical regions results in malformations comparable to those seen in the Di-George sequence and/or retinoic acid embryopathy. Slightly later, at the time that the epibranchial placodes are active, insult results in mandibulofacial dysostosis-like syndromes. We propose that the pattern of these malformations is related to the particular vulnerability of cells in the vicinity of normal programmed cell death. Cell death is also associated with ionizing radiation and hyperthermia-induced malformations. Both of these teratogens are particularly damaging to the early development of the eye and central nervous system. Teratogenic temperature elevations result in arrest of mitotic activity and death of cells in mitosis. Hypoxia is also associated with cell death in specific regions and subsequent malformation. For example, death of cells in the invaginating olfactory placode has recently been associated with cleft lip formation. The relationship of hypoxia-induced cell death to energy requirements is being explored. Acute treatment with methotrexate results in frontonasal dysplasia (median facial clefts). Combined effects of fluid imbalance, lack of proliferation or death of frontonasal mesenchyme appear to be involved. Although the mechanisms of craniofacial malformation are complex, a common feature for many is excessive cell death for which the embryo may be unable to compensate. Excessive cell death in regions of programmed cell death represents an important, yet little appreciated, mechanism of teratogenesis.
Strong anisotropic interaction controls unusual sticking and scattering of CO at Ru(0001)
Creators: name: Lončarić, Ivor
name: Füchsel, Gernot
name: Juaristi, J. I.
name: Saalfrank, Peter
Publisher: name: arXiv
Year: 2018
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Complete sticking at low incidence energies and broad angular scattering distributions at higher energies are often observed in molecular beam experiments on gas-surface systems which feature a deep chemisorption well and lack early reaction barriers. Although CO binds strongly on Ru(0001), scattering is characterized by rather narrow angular distributions and sticking is incomplete even at low incidence energies. We perform molecular dynamics simulations, accounting for phononic (and electronic) energy loss channels, on a potential energy surface based on first principles electronic structure calculations that reproduce the molecular beam experiments. We demonstrate that the mentioned unusual behavior is a consequence of a very strong rotational anisotropy in the molecule-surface interaction potential. Beyond the interpretation of scattering phenomena, we also discuss implications of our results for the recently proposed role of a precursor state for the desorption and scattering of CO from ruthenium.
description: 6 pages, 4 figures
title: Correspondence: Leslie C. Heller and C. Harrison Mann, Jr., July 24, 1962-August 2, 1962
Creators: name: Mann, Charles Harrison, Jr., 1908-1977
name: Heller, Leslie C.
Publisher: name: George Mason University
Year: 2007
Subjects: subject: Mental institutions

description: Letter A: 3 pgs, typescript signed, 8.5" x 11" (21.6 cm x 27.9 cm); Letter B: 2 pgs, typescript unsigned, 8.5" x 11" (21.6 cm x 27.9 cm)
description: Correspondence between Leslie C. Heller and C. Harrison Mann, Jr. regarding understaffing in Virginia's mental health facilities. Heller includes in her letter a copy of a letter she sent to Virginia Governor Albertis S. Harrison regarding the same subject. C. Harrison Mann, Jr. Collection 22.02
Retinoic acid-induced spina bifida: evidence for a pathogenetic mechanism
Creators: name: Alles, A J
name: Sulik, K K
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1990

description: Treatment of C57Bl/6J mice with three successive doses of all-trans retinoic acid (28 mg kg-1 body weight) on 8 day, 6 h (8d,6h), 8d,12h, and 8d,18h of gestation resulted in a high incidence (79%, 31/39 fetuses) of spina bifida with myeloschisis (spina bifida aperta) in near term fetuses. Twelve hours following the last maternal dose (9d,6h), the caudal aspects of treated embryos, were abnormal, with eversion of the neural plate at the posterior neuropore, as compared to its normal concavity in comparably staged control specimens. This eversion persisted in affected embryos through the time that the posterior neuropore should normally close. The distribution of cell death in control and experimental embryos was determined using vital staining with Nile blue sulphate and with routine histological techniques. Twelve hours following the maternal dosing regimen, experimental embryos showed evidence of excessive cell death, predominantly in the mesenchyme associated with the primitive streak and in the endoderm of the tail gut, both of which are readily identifiable sites of physiological cell death at this stage of development. In addition, the presumptive trunk neural crest cells located in the dorsal midline, cranial to the posterior neuropore, exhibited a marked amount of cell death in the experimental embryos. We propose that the major factor in the generation of spina bifida in this model is excessive cell death in the tail gut and mesenchyme ventral to the neuroepithelium of the posterior neuropore.(ABSTRACT TRUNCATED AT 250 WORDS)
Polar axis fixation in Fucus zygotes: components of the cytoskeleton and extracellular matrix
Creators: name: Quatrano, Ralph S
name: Aldridge, Joyce
name: Brian, Leigh
name: Schultz, Thomas
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: Polar axis formation and polar axis stabilization (or fixation) can be separated and analyzed in synchronously developing zygotes of the brown alga
Factorisation and Subtraction beyond NLO
Creators: name: Magnea, Lorenzo
name: Maina, Ezio
name: Pelliccioli, Giovanni
name: Signorile-Signorile, Chiara
name: Torrielli, Paolo
name: Uccirati, Sandro
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We provide a general method to construct local infrared subtraction counterterms for unresolved radiative contributions to differential cross sections, to any order in perturbation theory. We start from the factorised structure of virtual corrections to scattering amplitudes, where soft and collinear divergences are organised in gauge-invariant matrix elements of fields and Wilson lines, and we define radiative eikonal form factors and jet functions which are fully differential in the radiation phase space, and can be shown to cancel virtual poles upon integration by using completeness relations and general theorems on the cancellation of infrared singularities. Our method reproduces known results at NLO and NNLO, and yields substantial simplifications in the organisation of the subtraction procedure, which will help in the construction of efficient subtraction algorithms at higher orders.
description: 34 pages, 3 figures
Additional file 3: of The transcription factor PRO44 and the histone chaperone ASF1 regulate distinct aspects of multicellular development in the filamentous fungus Sordaria macrospora
Creators: name: Schumacher, David Immanuel
name: Lütkenhaus, Ramona
name: Altegoer, Florian
name: Teichert, Ines
name: Kück, Ulrich
name: Minou Nowrousian
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Figure S3. Southern blot analysis of Δcac2, Δrtt106 double mutants. A. Overview of the cac2 and rtt106 genomic loci in the wild type and the corresponding deletion mutants, with the probes for the Southern blot indicated. B. Strains Δrtt106,fus and Δcac2 were crossed and single ascospore isolates were obtained. Three single spore isolates were subjected to Southern blot analysis after digestion of genomic DNA with the indicated enzymes. The blots were probed with the indicated probes. The resulting signals are as expected for the single and double mutants. Triangles indicate the weak bands in two cases, the asterisks in the blot probed with the rtt106 deletion cassette indicate undigested high molecular weight DNA. (PDF 1231 kb)
Surface gravities for 15,000 Kepler stars measured from stellar granulation and validated with Gaia DR2 parallaxes
Creators: name: Pande, Durlabh
name: Bedding, Timothy R.
name: Huber, Daniel
name: Kjeldsen, Hans
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We have developed a method to estimate surface gravity (log g) from light curves by measuring the granulation background, similar to the "flicker" method by Bastien et al. (2016) but working in the Fourier power spectrum. We calibrated the method using Kepler stars for which asteroseismology has been possible with short-cadence data, demonstrating a precision in log g of about 0.05 dex. We also derived a correction for white noise as a function of Kepler magnitude by measuring white noise directly from observations. We then applied the method to the same sample of long-cadence stars as Bastien et al. We found that about half the stars are too faint for the granulation background to be reliably detected above the white noise. We provide a catalogue of log g values for about 15,000 stars having uncertainties better than 0.5 dex. We used Gaia DR2 parallaxes to validate that granulation is a powerful method to measure log g from light curves. Our method can also be applied to the large number of light curves collected by K2 and TESS.
description: accepted by MNRAS; added table1.dat (catalogue of log g values) as Ancilliary file; added Acknowledgement to Gaia project
Hierarchies without Symmetries from Extra Dimensions
Creators: name: Arkani-Hamed, Nima
name: Schmaltz, Martin
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It is commonly thought that small couplings in a low-energy theory, such as those needed for the fermion mass hierarchy or proton stability, must originate from symmetries in a high-energy theory. We show that this expectation is violated in theories where the Standard Model fields are confined to a thick wall in extra dimensions, with the fermions "stuck" at different points in the wall. Couplings between them are then suppressed due to the exponentially small overlaps of their wave functions. This provides a framework for understanding both the fermion mass hierarchy and proton stability without imposing symmetries, but rather in terms of higher dimensional geography. A model independent prediction of this scenario is non-universal couplings of the Standard Model fermions to the ``Kaluza-Klein'' excitations of the gauge fields. This allows a measurement of the fermion locations in the extra dimensions at the LHC or NLC if the wall thickness is close to the TeV scale.
description: 25 pages, 7 figures
Additional file 4: of The transcription factor PRO44 and the histone chaperone ASF1 regulate distinct aspects of multicellular development in the filamentous fungus Sordaria macrospora
Creators: name: Schumacher, David Immanuel
name: Lütkenhaus, Ramona
name: Altegoer, Florian
name: Teichert, Ines
name: Kück, Ulrich
name: Minou Nowrousian
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Figure S4. Southern blot analysis of Δcrc1 strains. A. Overview of the crc1 genomic locus in the wild type and the corresponding deletion mutant, with the probes for the Southern blot indicated. B. Southern blot analysis of the wild type, one primary transformant (T124.1) and nine single spore isolates of two different independent primary transformants after digestion of genomic DNA with the indicated enzymes. The blots were probed with the indicated probes. The resulting signals are as expected for the crc1 deletion for strains T124.1, S123582, S123587, S123615, S123617, S123635, S123637, and S123704 (6.8 kb band when probed with the deletion cassette, and no signal when probed with the gene-specific probe, whereas the wild type and non-deletion-carrying transformants give bands of 3.7 and 4.6 kb when probed with the deletion cassette, and a 8.2 kb band with the gene-specific probe). Deletion strains that were used in further experiments are labelled in red. (PDF 1362 kb)
Embryonic stem cell-derived cystic embryoid bodies form vascular channels : an in vitro model of blood vessel development
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: Murine embryonic stem cells can differentiate in vitro to form cystic embryoid bodies (CEB) that contain different structures and cell types. The blood islands are one such structure that consist of immature hematopoietic cells surrounded by endothelial cells, the first identifiable vascular cells. CEBs differentiated in vitro developed blood islands initially, and subsequently these blood islands matured to form vascular channels containing hematopoietic cells. Phase contrast microscopy demonstrated the presence of channels in mature CEBs grown in suspension culture, and high resolution light and electron microscopy showed that the cells lining these channels were endothelial cells. The channels appeared less organized than the vasculature of the mature yolk sac. The hematopoietic cells were occasionally seen 'flowing' through the CEB channels, although their numbers were reduced relative to the yolk sac. Analysis of primary CEB cultures showed the presence of cells with two characteristics of endothelial cells: approximately 30% of the cells labelled with fluorescent acetylated low density lipoprotein and a small number of cells were positive for von Willebrand's factor by immunostaining. Thus we conclude that a primitive vasculature forms in CEBs differentiated in vitro, and that not only primary differentiation of endothelial cells but also some aspects of vascular maturation are intrinsic to this cell culture system. CEBs are therefore a useful model for the study of developmental blood vessel formation.
title: Anforderungen und Rahmenwerk für den betrieblichen Datenschutz
Creators: name: Schmitt, Hartmut
name: Polst, Svenja
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: Datenschutz
subject: Anforderungserhebung
subject: Modellierung
subject: Lösungskonzeption
subject: Requirements Engineering
subject: agil

description: In diesem Beitrag berichten wir über einen Ansatz zur Entwicklung praxistauglicher und rechtskonformer Lösungen für den betrieblichen Datenschutz. Wir geben einen Überblick über unseren agilen Requirements Engineering-Prozess bei der Anforderungserhebung, Modellierung und Lösungskonzeption und berichten über die Besonderheiten, etwa beim Umgang mit gegensätzlichen Stakeholderinteressen und konkurrierenden Qualitätseigenschaften.
A model system for cell adhesion and signal transduction in Drosophila
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: Cells must cooperate and communicate to form a multicellular animal. Information about the molecules required for these processes have come from a variety of sources; the convergence between the studies of particular molecules by vertebrate cell biologists and the genes identified by scientists investigating development in
title: Tool-Supported Experiments for Continuously Collecting Data of Subjective Video Quality Assessments During Video Playback
Creators: name: Karras, Oliver
name: Klünder, Jil
name: Schneider, Kurt
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: requirements
subject: video
subject: video quality assessment
subject: tool
subject: experiment

description: In our research project ViViReq, we aspire to research what constitutes a good video in the context of requirements communication. As part of our research plan, we develop a quality model for videos to define and evaluate the quality of videos as RE artifacts. In addition to evaluating videos, this quality model can be used by software professionals as guidance for producing and using videos. Based on our quality model, we want to analyze how specific implementations of single video characteristics, e.g., pleasure, exactly affect the viewers’ quality assessment. In this research preview, we propose to support the conduct of experiments for subjective video quality assessments with a software tool which allows continuously collecting the assessment data for generic video characteristics during video playback. The proposed solution consists of five key concepts which are briefly explained in this article.
Hadron masses in qQCD with Wilson fermions near the chiral limit
Creators: name: Hoferichter, A.
name: Laermann, E.
name: Mitrjushkin, V. K.
name: Müller-Preussker, M.
name: Schmidt, P.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: In quenched lattice QCD with standard Wilson fermions the quark propagator is computed very close to the chiral limit in the zero-temperature case. Starting from our experience with lattice QED we employ a modified statistical method in order to estimate reliably hadron masses.
description: 8 (single column-) pages, contribution to LATTICE 97
ERADICATING HIV-1 RESERVOIRS: THE DEVELOPMENT OF DUAL-AGENTS FOR SIMULTANEOUSLY ACTIVATING HIV-1 LATENCY AND PREVENTING NEW INFECTION
Creators: name: Mitrevski, Adam D
Publisher: name: Purdue University Graduate School
Year: 2025
Subjects: classificationCode: 340502
subject: Natural products and bioactive compounds

description: The elimination of human immunodeficiency virus type-1 (HIV-1) from infected individuals persists as a major medical challenge. Although combined antiretroviral therapy (cART) has led to profound reduction in HIV-related morbidity and mortality, discontinuation of cART medications results in reinfection by HIV-1. This is due to latent reservoirs of replication-competent proviruses that persist within CD4+ memory cells, macrophages, and the central nervous system of HIV-positive patients.The shock and kill approach has been proposed to eradicate HIV reservoirs through the reactivation of latent provirus followed by the elimination of infected cells via immune-mediated clearance. However, it is imperative that reactivated reservoir cells must not produce new, infective virions. Most studies on the shock and kill approach to date utilize histone deacetylase inhibitors (HDACi’s) as the target for activating HIV-1 latency. We also identified HIV-1 protease (HIV PR) as the target for preventing new infection. Ideally, HDAC reactivation of HIV-1 latency should be spatially and temporally linked to the antiviral activity, leading to a need for dual-action agents targeting HIV PR and HDAC.Due to the lack of a resolved ligand-bound crystal structure of HDAC3, which is the isoform shown to be critical for latency reversal, we created a predicted fold of HDAC3 with RosettaFold®. In Schrodinger Maestro®, DESMOND molecular dynamics (MD) simulations with our molecular model led to the design of proposed dual HIV PR/HDAC3 inhibitors. The scaffolds for these compounds were derived from known, FDA-approved inhibitors of HIV PR and HDAC3. Dual inhibitors were synthesized and biologically evaluated against HIV PR and HDAC3, showing micromolar inhibition against both targets.
Control of CNS midline transcription by asymmetric E-box-like elements: Similarity to xenobiotic responsive regulation
Creators: name: Kasai, Y
name: Wharton, K A
name: Crews, S T
name: Franks, R G
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1994

description: Central nervous system midline cells constitute a discrete group of Drosophila embryonic cells with numerous functional and developmental roles. Corresponding to their separate identity, the midline cells display patterns of gene expression distinct from the lateral central nervous system. A conserved 5 base pair sequence (ACGTG) was identified in central nervous system midline transcriptional enhancers of three genes. Germ-line transformation experiments indicate that this motif forms the core of an element required for central nervous system midline transcription. The central nervous system midline element is related to the mammalian xenobiotic response element, which regulates transcription of genes that metabolize aromatic hydrocarbons. These data suggest a model whereby related basic-helix-loop-helix-PAS proteins interact with asymmetric E-box-like target sequences to control these disparate processes.
The Ratio of Jet Cross Sections at s**(1/2)=630 GeV and 1800 GeV
Creators: name: D0 Collaboration
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The DO Collaboration has measured the inclusive jet cross section in proton-antiproton collisions at s**2 = 630 GeV. The results for pseudorapidities -0.5 to 0.5 are combined with our previous results at s**2 = 1800 GeV to form a ratio of cross sections with smaller uncertainties than either individual measurement. Next-to-leading-order QCD predictions show excellent agreement with the measurement at 630 GeV; agreement is also satisfactory for the ratio. Specifically, despite a 10% to 15% difference in the absolute normalization, the dependence of the ratio on jet transverse momentum is very similar for data and theory.
description: 11 pages, 3 figures, 2 tables Note on V2: addressed PRL review comments with small wording changes. Note on V3: revised Figs. 2 and 3 with larger fonts and darker shading
title: A Darkroom
Creators: name: Tague, Melanie
Publisher: name: George Mason University
Year: 2022
Subjects: subject: Poetry
subject: Narrative
subject: Family

description: This thesis has been embargoed for 5 years and will not be available until April 2022 at the earliest.
description: A Darkroom is a poetic exploration of memory and loss within in a family unit. The backbone of this thesis is centered on a crown of sonnets that relies on film and innovation of the sonnet form to tell the story of the speaker and their relationship with their family.
Radiative decay of the lightest neutralino in an R-parity violating supersymmetric theory
Creators: name: Mukhopadhyaya, Biswarup
name: Roy, Sourov
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In an R-parity violating supersymmetric scenario, the lightest neutralino $\tilde χ^0_1$ is no longer a stable particle. We calculate the branching ratio for the decay mode $\tilde χ^0_1 \longrightarrow νγ$ which occurs at the one-loop level. Taking into account bilinear as well as trilinear lepton number violating interactions as the sources of R-parity violation, we make a detailed scan of the parameter space, both with and without gaugino mass unification and including the constraints on the neutrino sector from the recent Superkamiokande results. This study enables one to suggest interesting experimental signals distinguishing between the two types of R-parity breaking, and also to ascertain whether such radiative decays can give rise to collider signals of the type $γγ$ + $\not {\rm E}$ from pair-produced neutralinos.
description: 25 pages, LaTex including postscript figures. Uses axodraw.sty. Minor typographic errors corrected
Additional file 2: of The transcription factor PRO44 and the histone chaperone ASF1 regulate distinct aspects of multicellular development in the filamentous fungus Sordaria macrospora
Creators: name: Schumacher, David Immanuel
name: LĂźtkenhaus, Ramona
name: Altegoer, Florian
name: Teichert, Ines
name: KĂźck, Ulrich
name: Minou Nowrousian
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology

description: Figure S2. Co-immunoprecipitation of strain S198 expressing only egfp-pro44, but not ntap-pro44. TAP-tag-based immunoprecipitation was performed and the isolated proteins were analyzed by Western blot with an anti-GFP antibody. The part of the Western blot shown in Fig. 2 is labelled in red. Crude extract from the wild type as well as a result from a co-immunoprecipitation of strain S135826 expressing egfp-pro44 and ntap-pro44 were used as negative and positive controls, respectively. The unspecific band (green asterisk) seen in the region labelled in red (and in the wild type crude extract, green asterisk) is slightly lower than the EGFP-PRO44 protein detected in the co-IP of strain S135826 (blue asterisk). The Fig. shows a long exposure of the Western Blot detection to better visualize the unspecific bands. (PDF 214 kb)
title: Ties That Bind
Creators: name: Loda, Nathan
Publisher: name: George Mason University
Year: 2015
Subjects: subject: Art
subject: Painting
subject: History
subject: American
subject: Realism
subject: Culture

description: I started this series with a question, what is my identity? This led me to look at my childhood influences -- playmobil toys, adventure films, and my outdoor experiences – all of which started to inform the subject matter for the paintings. These influences led me to research more about the subject’s history and in turn, my own history. From a trove of artifacts, letters, photographs and family lore, I started using stories about ancestors as the narrative in my paintings, while continuing to use my childhood toys as symbolic representations. So began my series of paintings that explore the ties that bind people, places, and histories together. The paintings create open-ended and sometimes fictitious narratives that are derived from my ancestors’ stories. For example, a number of paintings follow the life of my fourth great grand father Cornelius K. Stribling. After forty years of service in the United States Navy, he had to cope with the death of his son, John Maxwell, who had left the Union to die in the Confederate Navy. Or my great great grandfather Ebenezer Lee Perry whose brother, Grant, went west in 1893 to work for the abolitionist American Missionary Association on the Fort Berthold Indian Reservation. Some of the recurring symbols and characters in the paintings, such as the little feathered doll I call the trickster, suggest that there is more than meets the eye, and perhaps things are not as they appear. Part of the reason for painting images or objects from the past is to call into question my own perceived understanding of history and perhaps imagine a different one. My hope is that these paintings offer an opportunity to examine the history of a country and culture that is continuously learning who it is through conflicting interpretations of shared histories.
Dilacreon (Eluzalmon) Fennah 1980
Creators: name: Chen, Xiang-Sheng
name: Zhi, Yan
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cixiidae
Dilacreon

description: Subgenus Dilacreon (Eluzalmon) Fennah, 1980
 Dilacreon (Eluzalmon) Fennah, 1980: 246; Zhang & Chen, 2013a: 318.
 Type species: Dilacreon (Eluzalmon) caudatus Fennah, 1980, by original designation.
 Diagnosis. Frons with lateral margins distinctly anterolaterally produced. Forewing without a crossvein from MP to CuA 1 near CuA fork.
description: Published as part of Chen, Xiang-Sheng & Zhi, Yan, 2023, Taxonomic study of the Eucarpiini (Hemiptera: Fulgoromorpha: Cixiidae) from China, pp. 1-100 in Zootaxa 5347 (1) on page 11, DOI: 10.11646/zootaxa.5347.1.1, http://zenodo.org/record/8390836
extradenticle determines segmental identities throughout Drosophila development
Creators: name: Smith, K M
name: Wieschaus, E
name: Rauskolb, C
name: Peifer, M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: extradenticle (exd) and the homeotic selector proteins together establish segmental identities by coordinately regulating the expression of downstream target genes. The inappropriate expression of these targets in exd mutant embryos results in homeotic transformations and aberrant morphogenesis. Here we examine the role of exd in adult development by using genetic mosaics and a hypomorphic exd allele caused by a point mutation in the homeodomain. exd continues to be essential for the specification of segmental identities, consistent with a continuing requirement for exd as cofactor of the homeotic selector proteins. Loss of exd results in the homeotic transformation of abdominal segments to an A5 or A6 segmental identity, the antenna and arista to leg, and the head capsule to dorsal thorax or notum. Proximal leg structures are particularly sensitive to the loss of exd, although exd does not affect the allocation of proximal positional values of the leg imaginal disc. Using heat-shocks to induce expression of a hsp70-exd fusion gene, we show that, in contrast to the homeotic selector genes, ubiquitously high levels of exd expression do not cause pattern abnormalities or segmental transformations.
title: Neue RE-Dimensionen für Digitale Ökosysteme
Creators: name: Koch, Matthias
Publisher: name: Gesellschaft für Informatik e.V.
Year: 2020
Subjects: subject: Anforderungen
subject: Ökosystem
subject: Umfrage
subject: Informationsbedarf

description: Zur systematischen Untersuchung relevanter Aspekte, die im Kontext digitaler Ökosysteme hinsichtlich der Ableitung von Anforderungen an eine zentrale Plattform vorliegen, haben wir eine empirische Studie durchgeführt. Ziel dieser Studie war es, Informationsbedarfe aus der Sicht eines Plattformbesitzers im Rahmen digitaler Ökosystemprojekte zu identifizieren. Durch die Interviewserie mit sieben Teilnehmern, die aktiv an digitalen Ökosystemprojekten beteiligt waren, haben wir 61 Informationsbedarfe im Hinblick auf Anforderungen an eine digitale Plattform identifiziert. Um die Anzahl der Elemente besser zu handhaben, haben wir sie manuell auf höchster Ebene in die folgenden Gruppen, die sich durch Betrachtung der Nennung der Teilnehmer ergaben, eingeordnet: Ist-Situation mit 44 Einträgen, Historie mit 3 Einträgen, Onboarding mit 10 Einträgen und Soll-Situation mit 4 Einträgen. Die gesammelten Informationsbedarfe weisen einen großen Anteil an geschäftsrelevanten Aspekten, die für die Entscheidungsfindung im Hinblick auf die zukünftigen Anforderungen an ein digitales Ökosystem bzw. dessen Plattform relevant sind, auf.
Progenitor cells of the adult human airway involved in submucosal gland development
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: A bronchial xenograft model of the human airway was used to identify submucosal gland progenitor cells within the surface airway epithelium. Lineage analysis using recombinant retroviruses has demonstrated considerable diversity in the cellular composition of expanded clones within reconstituted xenograft airway epithelium. These findings provide evidence for the existence of multiple progenitors in the airway with either limited or pluripotent capacity for differentiation. Furthermore, the development of transgene-expressing submucosal glands was associated with a single subset of surface airway epithelial clones. This gland progenitor cell demonstrated two discernible characteristics consistent with the identification of an airway stem cell including: (1) pluripotent capacity for airway differentiation and (2) a two-fold higher proliferative rate than other observed clone types. The number of progenitor cells involved in gland development was also assessed by clonal analysis using alkaline phosphatase and beta-galactosidase transgenes. These studies demonstrated that more than one airway progenitor cell is involved in the initial stages of gland development. A second explanation for the high prevalence of non-clonality in developing glands was suggested from three-dimensional reconstruction of transgene marked glands. These reconstruction experiments demonstrated that 27% of glands contained more than one duct to the surface airway epithelium. This observation suggests a novel mechanism of gland morphogenesis by which independently formed glands interact to join glandular lumens. Such a mechanism of glandular development and morphogenesis may play an important role in normal submucosal gland development and/or the progression of hypersecretory diseases of the adult human airway as seen in cystic fibrosis, chronic bronchitis and asthma. The identification of progenitor cells with the capacity to form submucosal glands has implications on the targets for gene therapy in cystic fibrosis.