cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Sellar and Parasellar pathologies: a comprehensive review on MRI
Creators: name: Sahni, Shivam
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Cancer
subject: Imaging sequences
subject: MR
subject: CNS

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To discuss various sellar and parasellar lesions with an emphasis on MR imaging To develop a comprehensive approach for driving to a differential diagnosis To emphasize the role of MR imaging in preoperative evaluation of sellar and parasellar...
In Vivo Inhibition of TRPC6 by SH045 Attenuates Renal Fibrosis in a New Zealand Obese (NZO) Mouse Model of Metabolic Syndrome
Creators: name: Zheng, Zhihuang
name: Xu, Yao
name: Krügel, Ute
name: Schaefer, Michael
name: Grune, Tilman
name: Nürnberg, Bernd
name: Köhler, May-Britt
name: Gollasch, Maik
name: Tsvetkov, Dmitry
name: Markó, Lajos
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: TRPC6
subject: UUO
subject: NZO mice
subject: inflammation
subject: fibrosis
subject: CKD
subject: SH045
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Metabolic syndrome is a significant worldwide public health challenge and is inextricably linked to adverse renal and cardiovascular outcomes. The inhibition of the transient receptor potential cation channel subfamily C member 6 (TRPC6) has been found to ameliorate renal outcomes in the unilateral ureteral obstruction (UUO) of accelerated renal fibrosis. Therefore, the pharmacological inhibition of TPRC6 could be a promising therapeutic intervention in the progressive tubulo-interstitial fibrosis in hypertension and metabolic syndrome. In the present study, we hypothesized that the novel selective TRPC6 inhibitor SH045 (larixyl N-methylcarbamate) ameliorates UUO-accelerated renal fibrosis in a New Zealand obese (NZO) mouse model, which is a polygenic model of metabolic syndrome. The in vivo inhibition of TRPC6 by SH045 markedly decreased the mRNA expression of pro-fibrotic markers (Col1 alpha 1, Col3 alpha 1, Col4 alpha 1, Acta2, Ccn2, Fn1) and chemokines (Cxcl1, Ccl5, Ccr2) in UUO kidneys of NZO mice compared to kidneys of vehicle-treated animals. Renal expressions of intercellular adhesion molecule 1 (ICAM-1) and alpha-smooth muscle actin (alpha-SMA) were diminished in SH045- versus vehicle-treated UUO mice. Furthermore, renal inflammatory cell infiltration (F4/80+ and CD4+) and tubulointerstitial fibrosis (Sirius red and fibronectin staining) were ameliorated in SH045-treated NZO mice. We conclude that the pharmacological inhibition of TRPC6 might be a promising antifibrotic therapeutic method to treat progressive tubulo-interstitial fibrosis in hypertension and metabolic syndrome.
Cosmological Constant from a Deformation of the Wheeler-DeWitt Equation
Creators: name: Garattini, Remo
name: Faizal, Mir
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we consider the Wheeler-DeWitt equation modified by a deformation of the second quantized canonical commutation relations. Such modified commutation relations are induced by a Generalized Uncertainty Principle. Since the Wheeler-DeWitt equation can be related to a Sturm-Liouville problem where the associated eigenvalue can be interpreted as the cosmological constant, it is possible to explicitly relate such an eigenvalue to the deformation parameter of the corresponding Wheeler-DeWitt equation. The analysis is performed in a Mini-Superspace approach where the scale factor appears as the only degree of freedom. The deformation of the Wheeler-DeWitt equation gives rise to a Cosmological Constant even in absence of matter fields. As a Cosmological Constant cannot exists in absence of the matter fields in the undeformed Mini-Superspace approach, so the existence of a non-vanishing Cosmological Constant is a direct consequence of the deformation by the Generalized Uncertainty Principle. In fact, we are able to demonstrate that a non-vanishing Cosmological Constant exists even in the deformed flat space. We also discuss the consequences of this deformation on the big bang singularity.
description: 11 pages, 0 figures, Accepted in Nucl. Phys. B
Risk, resilience, and depressive symptoms in low-income African American fathers.
Creators: name: Stanton, Annette L.
name: Schetter, Christine Dunkel
name: Thorp, John
name: Raju, Tonse
name: Lanzi, Robin Gaines
name: Schafer, Peter
name: Bamishigbin, Olajide N.
name: Shalowitz, Madeleine
name: Guardino, Christine M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: OBJECTIVE: Parental depression influences family health but research on low-income African American fathers is limited. The primary goal of the present study was to examine the role of paternal risk factors and resilience resources in predicting depressive symptoms in the year after birth of a child in a sample of African American fathers. We hypothesized that paternal risk factors (low socioeconomic status [SES], perceived stress, negative life events, racism, avoidant coping style) and resources (social support, self-esteem, collective efficacy, approach-oriented coping style) would predict depressive symptoms in fathers at 1 year postbirth controlling for depressive symptoms at 1 month postbirth.

METHOD: African American fathers (n = 296) of predominantly low SES from 5 U.S. regions were interviewed at 1 and 12 months after birth of a child regarding potential risk factors, resilience resources, and depressive symptoms.

RESULTS: Depressive symptoms were low on average. However, hierarchical linear regression analyses revealed that avoidant coping style and experiences of racism predicted more depressive symptoms in fathers nearly a year after the birth of a child controlling for symptoms at 1 month.

CONCLUSIONS: How fathers cope with stress and common everyday experiences of racism contributed to depressive symptoms in the year following birth of a child. Interventions that target race-related stressors and decrease avoidant coping may promote better outcomes in this important and understudied population. (PsycINFO Database Record
Design and early development of a UAV terminal and a ground station for laser communications
Creators: name: Carrasco-Casado, Alberto
name: Vergaz, Ricardo
name: Sanchez-Pena, Jose M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: A free-space laser communication system has been designed and partially developed as an alternative to standard RF links from UAV to ground stations. This project belongs to the SINTONIA program (acronym in Spanish for low environmental-impact unmanned systems), led by BR&TE (Boeing Research and Technology Europe) with the purpose of boosting Spanish UAV technology. A MEMS-based modulating retroreflector has been proposed as a communication terminal onboard the UAV, allowing both the laser transmitter and the acquisition, tracking and pointing subsystems to be eliminated. This results in an important reduction of power, size and weight, moving the burden to the ground station. In the ground station, the ATP subsystem is based on a GPS-aided two-axis gimbal for tracking and coarse pointing, and a fast steering mirror for fine pointing. A beacon-based system has been designed, taking advantage of the retroreflector optical principle, in order to determine the position of the UAV in real-time. The system manages the laser power in an optimal way, based on a distance-dependent beam-divergence control and by creating two different optical paths within the same physical path using different states of polarization.
description: 9 pages, 12 figures. Appears in Proceedings of the SPIE Security+Defence (Prague, Czech Republic, 2011)
Encouraging Additional Summer Enrollment (EASE)
Creators: name: Weiss, Michael
name: Anzelone, Caitlin
name: Headlam, Camielle
name: Boynton, Melissa
name: Gupta, Himani
name: Stein, Devon
Publisher: name: Open Science Framework
Year: 2022

description: Randomized trial testing 2 interventions designed to increase summer enrollment among community college students.
The effects of economic and sociocultural stressors on the well-being of children of Latino immigrants living in poverty.
Creators: name: Watamura, Sarah Enos
name: Perreira, Krista M.
name: Mendoza, Marina M.
name: Dmitrieva, Julia
name: Hurwich-Reiss, Eliana
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: This paper explored whether preschooler's physical (body mass index and salivary cortisol levels) and psychological (internalizing/externalizing behaviors) well-being were predicted by economic hardship as has been previously documented, and further whether parental immigration-related stress and/or acculturation level moderated this relationship in low-income Latino families.
Towards consensus on fear appeals
Creators: name: Peters, Gjalt - Jorn
name: Ruiter, Robert
name: ten Hoor, Gill
name: Kessels, Loes
name: Kok, Gerjo
Publisher: name: Open Science Framework
Year: 2022

description: The aim of this project is to establish a consensus regarding for which populations and behaviors (if any) fear appeals seem a wise choice as behavior change method. It originated with a debate in Health Psychology Review in early 2018.
title: Imaging findings after breast implant removal.
Creators: name: Francolin, Erica
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Prostheses
subject: Screening
subject: Complications
subject: Ultrasound
subject: MR
subject: Mammography
subject: Breast

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - Describe the main reasons for breast implant removal. - Describe the imaging findings in mammogram, ultrasound and magnetic resonance after explantation. - Reiterate the importance of clinical history for correct exam...
Epigenetic Dysfunction in Turner Syndrome Immune Cells
Creators: name: Whitmire, Jason K.
name: Thrasher, Bradly J.
name: Hong, Lee Kyung
name: Su, Maureen A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Turner syndrome (TS) is a chromosomal condition associated with partial or complete absence of the X chromosome that involves characteristic findings in multiple organ systems. In addition to well-known clinical characteristics such as short stature and gonadal failure, TS is also associated with T cell immune alterations and chronic otitis media, suggestive of a possible immune deficiency. Recently, ubiquitously transcribed tetratricopeptide repeat on the X chromosome (UTX), a histone H3 lysine 27 (H3K27) demethylase, has been identified as a downregulated gene in TS immune cells. Importantly, UTX is an X-linked gene that escapes X-chromosome inactivation and thus is haploinsufficient in TS. Mice with T cell-specific UTX deficiency have impaired clearance of chronic viral infection due to decreased frequencies of T follicular helper (Tfh) cells, which are critical for B cell antibody generation. In parallel, TS patients have decreased Tfh frequencies in peripheral blood. Together, these findings suggest that haploinsufficiency of the X-linked UTX gene in TS T cells underlies an immune deficit, which may manifest as increased predisposition to chronic otitis media.
Idea, orizzonte, totalità: verso una cosmologia fenomenologica
Creators: name: Terzi, Roberto
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2022

description: The article focuses on Husserl's phenomenology after referring to Kant's critique of metaphysical cosmology and highlighting the potential and limits of Kant's analysis through a reading of Fink. In particular, it analyses the fundamental concept of the horizon, through which Husserl attempts to think about the problem of the world in order to emphasise its richness and originality compared to the Kantian position. However, the Husserlian concept of the horizon also runs into substantial limitations, which prevent it from adequately accounting for the phenomenon of the world. These limitations also illustrate the problems that later phenomenologists had to deal with and the demands that a phenomenological cosmology must fulfil. The article's last part quickly outlines the features of these phenomenological cosmologies, mainly through Patočka's thought, according to which the world must be thought of as an original totality and as the true locus of the transcendental insofar as it is the condition of every experience and every single manifestation.
description: Thaumàzein | Rivista di Filosofia, Vol. 10 No. 2 (2022): Cosmologia filosofica / Philosophical Cosmology
Stress Reduction by Yoga versus Mindfulness Training in Adults Suffering from Distress: A Three-Armed Randomized Controlled Trial including Qualitative Interviews (RELAX Study)
Creators: name: Fischer, Jan Moritz
name: Kandil, Farid-Ihab
name: Kessler, Christian S.
name: Nayeri, Lucas
name: Zager, Laura Sophie
name: Rocabado Hennhöfer, Theresa
name: Steckhan, Nico
name: Koppold-Liebscher, Daniela A.
name: Bringmann, Holger C.
name: Schäfer, Thomas
name: Michalsen, Andreas
name: Jeitler, Michael
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: yoga
subject: iyengar yoga
subject: mindfulness
subject: meditation
subject: stress reduction
subject: mixed methods
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Distress is a growing public health concern. In this three-armed randomized controlled trial, n = 102 adults with elevated stress levels and stress-related symptoms were randomly assigned to (1) "integrative" yoga classes which combined physical exercises, mindfulness training, and ethical/philosophical aspects of traditional yoga; to (2) Iyengar yoga classes which entailed primarily physical exercises; or to (3) mindfulness training without physical training. We hypothesized the synergistic effects of physical yoga exercises, mindfulness, and ethical/philosophical aspects. The primary outcome was the group difference on Cohen's Perceived Stress Scale (PSS) after 12 weeks. Secondary outcomes included burnout, quality of life, physical complaints, depression, anxiety, mindfulness, interoceptive awareness, self-regulation, spirituality, mysticism, and posttraumatic stress. All outcomes were evaluated at baseline (V0), after 12 weeks (V1), and after 24 weeks (V2). A subset of participants took part in qualitative interviews. A lasting and clinically relevant stress reduction was observed within all groups (PSS Delta V0-V1(Integrative Yoga) = -6.69 +/- 6.19; Delta V0-V1(Iyengar Yoga) = -6.00 +/- 7.37; Delta V0-V1(Mindfulness) = -9.74 +/- 7.80; all p < 0.00). Effect sizes were also statistically large at the end of the follow-up period (Cohen's d (Integrative Yoga) = 1.41; d (Iyengar Yoga) = 1.37; d (Mindfulness) = 1.23). There were no significant group differences or evidence of relevant synergistic effects from combining mindfulness and physical yoga exercises. All three interventions were found to be equally effective methods of stress reduction. Their use in practice should be based on availability and patient preference.
Determination of $|V_{ub}|$ from exclusive baryonic $B$ decays
Creators: name: Hsiao, Y. K.
name: Geng, C. Q.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We use the exclusive baryonic $B$ decays to determine the Cabibbo-Kobayashi-Maskawa (CKM) matrix element $V_{ub}$. From the relation $|V_{ub}|^2/|V_{cb}|^2=({\cal B}_π/{\cal B}_D){\cal R}_{ff}$ based on $B^-\to p\bar p π^-$ and $\bar B^0\to p\bar p D^0$ decays, where $|V_{cb}|$ and ${\cal B}_π/{\cal B}_D\equiv{\cal B}(B^-\to p\bar p π^-)/{\cal B}(\bar B^0\to p\bar p D^0)$ are the data input parameters, while ${\cal R}_{ff}$ is the one fixed by the $B\to p\bar p$ transition matrix elements, we find $|V_{ub}|=(3.48^{+0.87}_{-0.63}\pm 0.40\pm 0.07)\times 10^{-3}$ with the errors corresponding to the uncertainties from ${\cal R}_{ff}$, ${\cal B}_π/{\cal B}_D$ and $|V_{cb}|$, respectively. Being independent of the previous results, our determination of $|V_{ub}|$ has the central value close to those from the exclusive $\bar B\to π\ell\bar ν_\ell$ and $Λ_b\to pμ^-\bar ν_μ$ decays, but overlaps the one from the inclusive $\bar B\to X_u \ell\bar ν_\ell$ with the current uncertainties. The extraction of $|V_{ub}|$ in the baryonic $B$ decays is clearly very useful for the complete determination of the CKM matrix elements as well as the exploration of new physics.
description: 7 pages, 1 figure, revised version accepted for publication in PLB
title: Diagnostic accuracy of 3d mrcp in comparision with conventional mri in the evaluation of normal anatomical variants and pathologies of the biliary tract.
Creators: name: Budigi, Bhavana
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: MR
subject: MR
subject: Gastrointestinal tract
subject: Biliary Tract / Gallbladder
subject: Abdomen
subject: Cholangiography
subject: Inflammation
subject: Obstruction / Occlusion
subject: Artifacts

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The expanding spectrum of biliary tract and gallbladder disease makes it necessary for the radiologist to precisely assess the normal anatomy, anatomical variants, pathology, etiology, location, level and extent of disease. This study aims to...
Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization
Creators: name: Soria-Tiedemann, Mariana
name: Michel, Geert
name: Urban, Iris
name: Aldrovandi, Maceler
name: O’Donnell, Valerie
name: Stehling, Sabine
name: Kuhn, Hartmut
name: Borchert, Astrid
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: sperm
subject: redox homeostasis
subject: fertility
subject: lipid peroxidation
subject: eicosanoids
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Glutathione peroxidase 4 (Gpx4) and arachidonic acid 15 lipoxygenase (Alox15) are counterplayers in oxidative lipid metabolism and both enzymes have been implicated in spermatogenesis. However, the roles of the two proteins in acrosomal exocytosis have not been explored in detail. Here we characterized Gpx4 distribution in mouse sperm and detected the enzyme not only in the midpiece of the resting sperm but also at the anterior region of the head, where the acrosome is localized. During sperm capacitation, Gpx4 translocated to the post-acrosomal compartment. Sperm from Gpx4(+/Sec46Ala) mice heterozygously expressing a catalytically silent enzyme displayed an increased expression of phosphotyrosyl proteins, impaired acrosomal exocytosis after in vitro capacitation and were not suitable for in vitro fertilization. Alox15-deficient sperm showed normal acrosome reactions but when crossed into a Gpx4-deficient background spontaneous acrosomal exocytosis was observed during capacitation and these cells were even less suitable for in vitro fertilization. Taken together, our data indicate that heterozygous expression of a catalytically silent Gpx4 variant impairs acrosomal exocytosis and in vitro fertilization. Alox15 deficiency hardly impacted the acrosome reaction but when crossed into the Gpx4-deficient background spontaneous acrosomal exocytosis was induced. The detailed molecular mechanisms for the observed effects may be related to the compromised redox homeostasis.
Unintended Immunological Consequences of Biologic Therapy
Creators: name: Ruffner, Melanie A.
name: Henrickson, Sarah E.
name: Kwan, Mildred
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Recent advances in the understanding of immune dysregulation in autoimmune diseases have enabled the development of new monoclonal antibody based drugs called biologics. Biologics have been used to target aberrant immune responses in many diseases, but patients with rheumatologic and other autoimmune diseases have benefited the most and improvements in outcomes have been significant. The use of biologics is not without hazard; however, as these agents block immune pathways adapted to protect the host. This has been borne out by increased rates of infections as well as induction of new autoimmune and hematologic adverse effects. As new drugs for the treatment of autoimmune conditions are entering the pipeline, it is incumbent on the practicing immunologist to understand the mechanism of these biologics and the implications of clinical use.
New class of planar ferroelectric Mott insulators via first principles design
Creators: name: Kim, Chanul
name: Park, Hyowon
name: Marianetti, Chris A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Inorganic perovskite oxide ferroelectrics have recently generated substantial interest for photovoltaic applications; however, existing materials suffer from excessive electronic band gaps and insufficient electric polarization. The recent resurgence of hybrid perovskite ferroelectrics addresses the aforementioned deficiencies, but they are highly unstable against environmental effects and an inorganic resolution may still be optimal. Here we use first-principles calculations to design a low band gap, planar ferroelectric by leveraging the complexity of layered double perovskite oxides AA$^\prime $BB$^\prime$O$_6$. We exploit A$\ne$A$^\prime$ size mismatch, a nominally empty $d$-shell on the B-site, and A cations bearing lone-pair electrons to achieve a large ferroelectric polarization. Additionally, B$^\prime\ne$B is chosen to achieve full charge transfer and a Mott susceptible filling on the B$^\prime$-site, yielding a low band gap. These principles are illustrated in BaBiCuVO$_6$, BaBiNiVO$_6$, BaLaCuVO$_6$, and PbLaCuVO$_6$, which could be realized in layer-by-layer growth. This new class of materials could lead to stable, high-efficiency photovoltaic.
description: 8 pages; 4 figures and 1 table for main text; 2 figures and 4 tables for supplemental material
A Review of Electronic Devices to Assess Inhaler Technique
Creators: name: George, Johnson
name: Sage, Adam J.
name: Carpenter, Delesha M.
name: Roberts, Courtney A.
name: Horne, Robert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Multiple electronic devices exist that provide feedback on the accuracy of patient inhaler technique. Our purpose is to describe the inhaler technique feedback provided by these devices, including specific technique steps measured, how feedback is displayed, target of feedback (patient, provider, researcher), and compatibility with inhaler type (metered-dose inhaler [MDI], diskus, etc.).
Sensitivity of Cutaneous T-Cell Lymphoma Cells to the Mcl-1 Inhibitor S63845 Correlates with the Lack of Bcl-w Expression
Creators: name: Sumarni, Uly
name: Zhu, Jiaqi
name: Sinnberg, Tobias
name: Eberle, Jürgen
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: non-Hodgkin lymphoma
subject: Bcl-2 proteins
subject: BH3 mimetics
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Long-term, curative treatment of cutaneous T-cell lymphomas (CTCL) remains a major challenge. Therapy resistance is often based on apoptosis deficiency, and may depend on antiapoptotic Bcl-2 proteins, such as Bcl-2, Bcl-x(L), Bcl-w and Mcl-1. For their targeting, several antagonists have been generated, which mimic the Bcl-2 homology domain 3 (BH3 mimetics). As dysregulation and overexpression of Mcl-1 has been reported in CTCL, the use of Mcl-1 inhibitors appears as an attractive strategy. Here, we investigated the effects of the selective Mcl-1 inhibitor S63845 in a series of four CTCL cell lines, in comparison to ABT-263 and ABT-737 (inhibitors of Bcl-2, Bcl-x(L) and Bcl-w). In two cell lines (HH, HuT-78), S63845 resulted in significant apoptosis induction, decrease in cell viability, loss of mitochondrial membrane potential and caspase activation, while two other cell lines (MyLa, SeAx) remained completely resistant. An inverse correlation was found, as S63845-resistant cells were highly sensitive to ABT-263/-737, and S63845-sensitive cells showed only moderate sensitivity to ABTs. Combinations of S63845 and ABT-263 partially yielded synergistic effects. As concerning Bcl-2 protein expression, weaker Mcl-1 expression was found in S63845-resistant MyLa and SeAx, while for Bcl-2 and Bcl-x(L), the lowest expression was found in the highly sensitive cell line HH. The most striking difference between S63845-resistant and -sensitive cells was identified for Bcl-w, which was exclusively expressed in S63845-resistant cells. Thus, CTCL may be efficiently targeted by BH3 mimetics, providing the right target is preselected, and Bcl-w expression may serve as a suitable marker.
title: Pitfalls of MRCP: What every radiologist must know!
Creators: name: Budigi, Bhavana
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Gastrointestinal tract
subject: Gastrointestinal tract
subject: MR
subject: Cholangiography
subject: Artifacts

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To assess pitfalls associated with MRCP in the evaluation of biliary tract and gallbladder. To illustrate the frequency of pitfalls, enumerate the causes and discuss troubleshooting...
title: "Hide and seek: multimodality diagnostic approach of invasive lobular carcinoma of the breast"
Creators: name: Catalá Isla, Andrés
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Education and training
subject: Cancer
subject: Imaging sequences
subject: Education
subject: Biopsy
subject: Ultrasound-Colour Doppler
subject: MR
subject: Mammography
subject: Breast

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of our educational exhibit is to: 1) Describe the most frequent imaging appearances of invasive lobular carcinoma (ILC) in mammography, ultrasound (US) and magnetic resonance imaging (MRI). 2) Compare the value of mammography, US and MRI...
Investigating Established EEG Parameter During Real-World Driving
Creators: name: Protzak, Janna
name: Gramann, Klaus
Publisher: name: Technische Universität Berlin
Year: 2018
Subjects: subject: 150 Psychologie
subject: MoBI
subject: real driving
subject: P300
subject: electroencephalography
subject: auditory feedback
subject: EEG

description: In real life, behavior is influenced by dynamically changing contextual factors and is rarely limited to simple tasks and binary choices. For a meaningful interpretation of brain dynamics underlying more natural cognitive processing in active humans, ecologically valid test scenarios are essential. To understand whether brain dynamics in restricted artificial lab settings reflect the neural activity in complex natural environments, we systematically tested the auditory event-related P300 in both settings. We developed an integrative approach comprising an initial P300-study in a highly controlled laboratory set-up and a subsequent validation within a realistic driving scenario. Using a simulated dialog with a speech-based input system, increased P300 amplitudes reflected processing of infrequent and incorrect auditory feedback events in both the laboratory setting and the real world setup. Environmental noise and movement-related activity in the car driving scenario led to higher data rejection rates but revealed comparable theta and alpha frequency band pattern. Our results demonstrate the possibility to investigate cognitive functions like context updating in highly artifact prone driving scenarios and encourage the consideration of more realistic task settings in prospective brain imaging approaches.
title: Accuracy of vertebral fracture assessment (VFA) by GE- iDXA scanner in comparison to conventional radiography
Creators: name: Diacinti, Davide
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Bones
subject: Absorptiometry / Bone densitometry
subject: Conventional radiography
subject: Diagnostic procedure
subject: Osteoporosis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Vertebral fractures (VF) are the most common of all osteoporotic fractures, occurring in approximately 25% of postmenopausal women(1,2)and men (3) . Most of VFs are clinically asymptomatic and as a consequence they often remain undiagnosed, and...
Low-Impact Air-to-Ground Free-Space Optical Communication System Design and First Results
Creators: name: Carrasco-Casado, Alberto
name: Oton, Eva
name: Vergaz, Ricardo
name: Geday, Morten A.
name: Sanchez-Pena, Jose M.
name: Oton, Jose M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: An air-to-ground free-space optical communication system has been designed and partially developed. The design covers both the communications between the airborne and the ground station, and the acquisition, tracking and pointing. A strong effort has been made in order to achieve the minimum payload power, size and weight, for which a MEMS modulating retroreflector has been chosen. In the ground station, a new technique for fine pointing, based on a liquid crystal device, is proposed and will be demonstrated, as well as other improvements with the aim of optimizing the ground station performance.
description: 4 pages, 9 figures, IEEE 2011 International Conference on Space Optical Systems and Applications (ICSOS). arXiv admin note: substantial text overlap with arXiv:1506.08854
title: Manuel Mexia da Silva
Creators: name: Serrão, Vera da Cunha
name: Conceição, Margarida
Publisher: name: CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa
Year: 2022

description: Entrada biográfica sobre Manuel Mexia da Silva, na plataforma eViterbo
description: Serrão, Vera da Cunha e Conceição, Margarida Tavares da. 2022. Manuel Mexia da Silva in eViterbo. CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa. eISBN: 978-989-8492-77-7
Jean de Muralt (deputé de Montreaux, Président du Grand Conseil vaudois)
Creators: name: (:Unkn) Unknown
Publisher: name: La Patrie Suisse
Year: 1920
Subjects: subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Muralt, Jean de
subject: Montreux

description: In: La Patrie suisse, No. 702, le 18 Août 1920
The role of tumour vasculature in fluid flow and drug transport in solid tumours
Creators: name: Alamer, Moath Zaid
Publisher: name: Imperial College London
Year: 2019

description: The aberrance of the vasculature in tumours has been linked to increased aggressiveness and poor drug delivery in tumours. Complexities in the microarchitecture of tumour vasculature occurring on microscopic scales can affect fluid flow and drug transport making it difficult to predict tumour response to treatment. Given this, mathematical models can play an important role in understanding the various aspects of the tumour vasculature that can promote invasiveness and limit drug delivery. In this work, computational models are developed to investigate the effect of tumour vasculature on fluid flow and drug distribution and novel imaging methods are assessed for their ability to characterise the tumour vasculature in whole human tumours. A mathematical angiogenesis model is used to generate microscopic details including individual vessel properties on a whole vascular network scale which are coupled with a fluid flow and drug transport model. The interstitial fluid pressure (IFP) in the tumour model was found to be elevated with increased heterogeneity caused by the presence of a necrotic core and heterogenous vessel permeability. Subtle changes to the network on a microscopic scale significantly influenced fluid flow in the tumour vessels and tissue. Delivery of doxorubicin to tumours was found to be highly dependent on the properties of tumour vasculature and blood flow, where regions with excessive branching and vessel tortuosity had reduced drug concentrations due to poor blood flow. Hence, the vascular density was not found to be the main factor in the accumulation of the drug within the tissue space and it’s uptake by cancer cells. An interplay between treatment strategy including dose and administration mode and properties of the vasculature was found by evaluating the spatial intracellular concentration. The fluid flow and drug transport models showed the significant effect of incorporating the microscopic properties of the tumour vasculature which can influence fluid flow and drug distribution on a macroscopic scale. The imaging methods assessed in this work shows that Optical projection tomography combined with fluorescent Immunohistochemistry labelling methods can be used to extract angiogenesis related parameters in whole human tumours. Additionally, the method was able to extract clean network topologies that show promise in application to understanding fluid flow and drug transport in real tumours.
Aktion 1. Juli in Berlin; 1965
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Technischen Universität Berlin
Year: 2018

description: Enthält: Aufruf zur Demonstration und Kundgebung am 1. Juli 1965.- Weitere Veranstaltungen an der Freien Universität, der Kirchlichen Hochschule und der Staatlichen Ingenieurschule Gauß am 28. Juni, 30. Juni und 1. Juli 1965.- Sitzung des Berufsschulparlaments am 1. Juli 1965.- Aktion 1. Juli zum Bildungsnotstand. 1 Seite. S/w.
title: Quantitative 1HMR Spectroscopy as a predictive biomarker of Pathological Complete Response during Neoadjuvant Chemotherapy for Localy Advanced Breast Cancer : results from early response assessement
Creators: name: Drisis, Stylianos
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Cancer
subject: Diagnostic procedure
subject: MR-Spectroscopy
subject: MR-Diffusion/Perfusion
subject: Oncology
subject: Breast

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To explore if early changes in the concentration oftotal choline –containing compounds tCho mesured by quantitative 1HMR spectroscopy (MRS) could predict pathological complete response (pCR) during neoadjuvant chemotherapy (NAC) for patients with...
title: When fat is good news: lipoid pneumonia, an overlooked differential diagnosis
Creators: name: Popirtac, Ana
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Education and training
subject: Education
subject: PET-CT
subject: Digital radiography
subject: CT
subject: Thorax
subject: Respiratory system
subject: Lung

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Lipoid pneumonia (LP) is an uncommon disease triggered by a foreign body reaction caused by the presence of fatty material in the alveoli. Main learning points: classification diagnosis complications imaging findings differential...
title: Efficacy of an Automatic Decision Support System in Facilitating Diagnosis of the Breast Diseases
Creators: name: Hashoul, Sharbell
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: Mammography
subject: Ultrasound
subject: Efficacy studies
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To assess the clinical applicability of a novel Decision Support System (DSS) in the diagnosis of breast disease. Specifically, we aim to compare the performance of the DSS to the accuracy of decisions made by junior radiologists, suggesting that...
Development of a dry linear compressor for GM and pulse tube cryocoolers
Creators: name: Höhne, Jens
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Pressure Wave Systems GmbH has developed a dry compressor for GM and pulse tube cryocoolers. The concept is based on hydraulically driven metal bellows in which the Helium working gas is compressed. The system is operated in the region of 1 kW of electrical input power and has been successfully tested with a SHI RDK-101D GM cryocooler cold head. Set-up, performance and reliability of the compressor system will be discussed.
description: 4 pages, 4 figures, CEC/ICMC 2015 conference, Tuscon, Arizona
Devereux Slough Solinst Levelogger data (2018–2022)
Creators: name: Rickard, Alison
Publisher: name: Zenodo
Year: 2023
Subjects: pressure transducer
Solinst
Hydrology
Estuaries
Water quality

description: The Devereux Slough is a temporary open-closed estuary (TOCE). There are pressure transducers placed throughout the watershed wich measure water depth fluctuations. Some pressure transducers that are closer to the mouth can detect breach events by recording tidal influence and salinity changes. Others are placed in freshwater inlets that typically only pick up water depth changes during large storms.
description: All data is in CSV format.Funding provided by: U.S. Fish and Wildlife Service
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000202
Award Number: 20151208
description: This data has been collected with Solinst devices listed on the Hydrology_equipment_data.csv sheet. Known elevation reference points are used to calculate the elevation of water surface. The data is not processed therefore any malfunctions in the devices are reflected in the data. Any gaps in data are due to removal and maintenance.
Distribution of a Chimpanzee Social Custom Is Explained by Matrilineal Relationship Rather Than Conformity
Creators: name: Machanda, Zarin P.
name: Rosen, Jeremiah
name: Wrangham, Richard W.
name: Muller, Martin N.
name: Bernard, Andrew B.
name: Otali, Emily
name: Koops, Kathelijne
name: Brazeau, Nicholas F.
name: Donovan, Ronan
name: Worthington, Steven
name: Wilke, Claudia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: High-arm grooming is a form of chimpanzee grooming in which two individuals mutually groom while each raising one arm. Palm-to-palm clasping (PPC) is a distinct style of high-arm grooming in which the grooming partners clasp each other's raised palms. In wild communities, samples of at least 100 observed dyads grooming with raised hands showed PPC frequencies varying from 30% dyads grooming (Kanyawara, Kibale), and in a large free-ranging sanctuary group, the frequency reached >80% dyads (group 1, Chimfunshi) [1, 2]. Because between-community differences in frequency of PPC apparently result from social learning, are stable across generations, and last for at least 9 years, they are thought to be cultural, but the mechanism of transmission is unknown [2]. Here, we examine factors responsible for individual variation in PPC frequency within a single wild community. We found that in the Kanyawara community (Kibale, Uganda), adults of both sexes varied widely in their PPC frequency (from 50%) and did not converge on a central group tendency. However, frequencies of PPC were highly consistent within matrilines, indicating that individuals maintained lifelong fidelity to the grooming style of their mothers. Matrilineal inheritance of socially learned behaviors has previously been reported for tool use in chimpanzees [3] and in the vocal and feeding behavior of cetaceans [4, 5]. Our evidence indicates that matrilineal inheritance can be sufficiently strong in nonhuman primates to account for long-term differences in community traditions.
title: Pictorial review of the spectrum of cross-sectional imaging findings in patients with intra-abdominal hematomas.
Creators: name: Ahmed, Najeeb
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Trauma
subject: Education and training
subject: Blood
subject: Education
subject: Diagnostic procedure
subject: Complications
subject: MR
subject: CT-Angiography
subject: CT
subject: Vascular
subject: Trauma
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: In this pictorial review we present thespectrum of cross sectionalfindings in patients with non-traumatic intra-abdominal hematomas, the various locations of haematomas, underlying pathologies highlighting the most useful imaging features which help...
Feedback-Controlled Transcranial Alternating Current Stimulation Reveals a Functional Role of Sleep Spindles in Motor Memory Consolidation
Creators: name: Mellin, Juliann M.
name: Vaughn, Bradley V.
name: Fröhlich, Flavio
name: Boyle, Michael R.
name: Alagapan, Sankaraleengam
name: Lustenberger, Caroline
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Transient episodes of brain oscillations are a common feature of both the waking and sleeping brain. Sleep spindles represent a prominent example of a poorly understood transient brain oscillation that is impaired in disorders such as Alzheimer’s disease and schizophrenia. Yet, the causal role of these bouts of thalamo-cortical oscillations remains unknown. Demonstrating a functional role of sleep spindles in cognitive processes has so far been hindered by the lack of a tool to target transient brain oscillations in real-time. Here, we show for the first time selective enhancement of sleep spindles with non-invasive brain stimulation in humans. We developed a system that detects sleep spindles in real-time and applies oscillatory stimulation. Our stimulation selectively enhanced spindle activity as determined by increased sigma activity after tACS application. This targeted modulation caused significant enhancement of motor memory consolidation that correlated with the stimulation-induced change in fast spindle activity. Strikingly, we found a similar correlation between motor memory and spindle characteristics during the sham night for the same spindle frequencies and electrode locations. Therefore, our results directly demonstrate a functional relationship between oscillatory spindle activity and cognition.
Hubble Tarantula Treasury Project. IV. The extinction law
Creators: name: De Marchi, Guido
name: Panagia, Nino
name: Sabbi, Elena
name: Lennon, Daniel
name: Anderson, Jay
name: van der Marel, Roeland
name: Cignoni, Michele
name: Grebel, Eva K.
name: Larsen, Soeren
name: Zaritsky, Dennis
name: Zeidler, Peter
name: Gouliermis, Dimitrios
name: Aloisi, Alessandra
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report on the study of interstellar extinction across the Tarantula nebula (30 Doradus), in the Large Magellanic Cloud, using observations from the Hubble Tarantula Treasury Project in the 0.3 - 1.6 micron range. The considerable and patchy extinction inside the nebula causes about 3500 red clump stars to be scattered along the reddening vector in the colour-magnitude diagrams, thereby allowing an accurate determination of the reddening slope in all bands. The measured slope of the reddening vector is remarkably steeper in all bands than in the the Galactic diffuse interstellar medium. At optical wavelengths, the larger ratio of total-to-selective extinction, namely Rv = 4.5 +/- 0.2, implies the presence of a grey component in the extinction law, due to a larger fraction of large grains. The extra large grains are most likely ices from supernova ejecta and will significantly alter the extinction properties of the region until they sublimate in 50 - 100 Myr. We discuss the implications of this extinction law for the Tarantula nebula and in general for regions of massive star formation in galaxies. Our results suggest that fluxes of strongly star forming regions are likely to be underestimated by a factor of about 2 in the optical.
description: 15 pages, 10 figures, accepted for publication in MNRAS; Updated references, corrected typos in Table 3
MRCK-1 Drives Apical Constriction in  C. elegans  by Linking Developmental Patterning to Force Generation
Creators: name: Goldstein, Bob
name: Higgins, Christopher D.
name: Cox, Amanda H.
name: Marston, Daniel J.
name: Moore, Regan P.
name: Kiehart, Daniel P.
name: Peters, Kimberly A.
name: Dickinson, Daniel J.
name: Pani, Ariel M.
name: Cupp, Timothy D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Apical constriction is a change in cell shape that drives key morphogenetic events including gastrulation and neural tube formation. Apical force-producing actomyosin networks drive apical constriction by contracting while connected to cell-cell junctions. The mechanisms by which developmental patterning regulates these actomyosin networks and associated junctions with spatial precision are not fully understood. Here, we identify a myosin light chain kinase MRCK-1 as a key regulator of C. elegans gastrulation that integrates spatial and developmental patterning information. We show that MRCK-1 is required for activation of contractile actomyosin dynamics and elevated cortical tension in the apical cell cortex of endodermal precursor cells. MRCK-1 is apically localized by active Cdc42 at the external, cell-cell contact-free surfaces of apically constricting cells, downstream of cell fate determination mechanisms. We establish that the junctional components α-catenin, β-catenin, and cadherin become highly enriched at the apical junctions of apically-constricting cells, and that MRCK-1 and myosin activity are required in vivo for this enrichment. Taken together, our results define mechanisms that position a myosin activator to a specific cell surface where it both locally increases cortical tension and locally enriches junctional components to facilitate apical constriction. These results reveal crucial links that can tie spatial information to local force generation to drive morphogenesis.
title: Aggressive Angiomyxoma: A rare pelvic mesenchymal neoplasm with a review of the anatomy and primary soft tissue masses of the perineum and pelvic retroperitoneum
Creators: name: Cullen, Anthony
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Tissue characterisation
subject: Pathology
subject: Cancer
subject: Surgery
subject: Contrast agent-intravenous
subject: Comparative studies
subject: Ultrasound
subject: MR
subject: CT
subject: Pelvis
subject: Oncology
subject: Anatomy

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Describe the aetiology, presentation, imaging characteristics and management of Aggressive Angiomyxoma. Describe the anatomy of the female perineum and pelvic retroperitoneal spaces. Review the primary pelvic retroperitoneal masses and their...