cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Association between pregnancy at enrollment into HIV care and loss to care among women in the Democratic Republic of Congo, 2006-2013
Creators: name: Lelo, P.
name: Ross, J.
name: Hoover, D.R.
name: Anastos, K.
name: Yotebieng, M.
name: Shi, Q.
name: Behets, F.
name: Edmonds, A.
Publisher: name: Public Library of Science
Year: 2018

description: Background Loss to care is high among asymptomatic HIV-infected women initiated on antiretroviral therapy (ART) during pregnancy or in the postpartum period. However, whether pregnancy itself plays a role in the high loss to care rate is uncertain. We compared loss to care over seven years between pregnant and non-pregnant women at enrollment into HIV care in the Democratic Republic of Congo (DRC). Methods We conducted a retrospective analysis of all ART-naive women aged 15-45 initiating HIV care at two large clinics in Kinshasa, DRC, from 2007-2013. Pregnancy status was recorded at care enrollment. Patients were classified as having no follow-up if they did not return to care after the initial enrollment visit. Among those with at least one follow-up visit after enrollment, we classified patients as lost to care if more than 365 days had passed since their last clinic visit. We used logistic regression to model the association between pregnancy status and no follow-up, and Cox proportional hazards regression to model the association between pregnancy status and time to loss to care. Results Of 2175 women included in the analysis, 1497 (68.8%) were pregnant at enrollment. Compared to non-pregnant women, pregnant women were less likely to be over 35 years of age (19.1% vs. 31.9%, p<0.0001) and less likely to be in WHO stage III or IV (9.0% vs. 26.3%, p<0.0001). Among pregnant women, 106 (7.1%) were not seen after enrollment, versus 25 (3.7%) non-pregnant women (adjusted odds ratio 2.01, 95% CI 1.24-3.24). Of the 2,044 women with at least one follow-up visit, 46.5% of pregnant women and 46.7% of non-pregnant women were lost to care by 5 years; hazards of loss to care were similar for pregnant and non-pregnant women (adjusted hazard ratio 1.08, 95% CI 0.93-1.26). Conclusions In this large cohort of HIV-infected women, patients pregnant at care enrollment were more likely to never return for follow-up. Among those who attended at least one follow-up visit, loss to care was not different between pregnant and non-pregnant women, suggesting that pregnancy itself may not be the main driver of the high attrition observed in this cohort.
Epidemiologie Vancomycin-resistenter Enterokokken in Krankenhäusern in Deutschland
Creators: name: Remschmidt, Cornelius Christian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Enterococci
subject: Vancomycin-Resistance
subject: VRE
subject: Epidemiology
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Die vorliegende Habilitationsschrift beschäftigt sich mit der Epidemiologie Vancomycin-resistenter Enterokokken in Deutschland. Dabei wird gezeigt, dass die VRE-Rate unter Enterokokken-Infektionen in den letzten Jahren in deutschen Krankenhäusern kontinuierlich zugenommen hat. Besonders ausgeprägt ist dieser Anstieg auf Intensivstationen, wo im Jahr 2016 bereits jede sechste Enterokokken-Blutstrominfektion (BSI) durch VRE bedingt war. Dieser kontinuierliche Anstieg wird aufgrund der höheren Liegedauer und einer erhöhten Letalität bei einer Enterokokken-BSI mit Vancomycin-sensiblen und Vancomycin-resistenten E. faecium im Vergleich zu E. faecalis auch enorme Auswirkungen auf die Kosten des Gesundheitssystems haben. Die Ergebnisse dieser Arbeit zeigen weiterhin, dass die zunehmende Anwendung spezifischer Breitspektrumantibiotika aber auch die zunehmende VRE-Prävalenz bei Patienten in Krankenhäusern die Ausbreitung von VRE weiter begünstigen. Dies unterstreicht die Notwendigkeit der Implementierung von Antibiotic Stewardship-Teams und von krankenhaushygienischen Maßnahmen. Aufgrund des komplexen Selektionsprozesses von VRE, der persistierenden Kolonisierung im Gastrointestinaltrakt sowie fehlender effektiver Dekolonisationsmaßnahmen sind die bei MRSA erfolgreichen Präventionsmaßnahmen bei VRE nicht ausreichend und müssen weiter diskutiert und angepasst werden. Um die Epidemiologie von VRE, regionalen Unterschiede und die Ausbreitungswege relevanter klonaler Linien besser zu verstehen, sollte außerdem die mikrobiologische Diagnostik und insbesondere die Genotypisierung von Enterokokken weiter intensiviert werden.
SIGNIFICANCE OF ONLINE COLLABORATION TOOLS IN ENHANCING COMMUNICATION AND ENGAGEMENT AMONG ESP STUDENTS
Creators: name: Rashidova, Munavvar
Publisher: name: Zenodo
Year: 2024

description: This article explores the significance of online collaboration tools in modern education, highlighting their role in enhancing communication, engagement, and project management among students and educators. By facilitating real-time interaction and collaborative work, these tools promote active learning and inclusivity, catering to diverse learning styles. The article emphasizes the importance of developing essential skills such as teamwork and digital literacy, preparing students for the demands of the modern workforce. Additionally, it discusses the role of educators in effectively integrating these tools into their teaching practices, fostering environments that support collaboration and critical thinking.
Constituent System Design: A Software Architecture Approach
Creators: name: Teixeira, Paulo Gabriel
name: Lebtag, Bruno Araújo Lebtag
name: Santos, Rodrigo Pereira dos
name: Fernandes, Juliana
name: Mohsin, Ahmad
name: Kassab, Mohamad
name: Graciano Neto, Valdemar Vicente
Publisher: name: Zenodo
Year: 2020
Subjects: systems-of-systems, constituent systems, software architecture

description: Over the years, knowledge on how to engineer software-intensive system-of-systems (SoS) have been expanded and advanced. With the emergence of smart cities, which is a remarkable example of SoS, there is also an emerging need that almost any type of system should be prepared to join the smart city system and become a constituent of that SoS, even temporarily. However, several attempts to build a real SoS have stumbled on the limitations of single systems, also known as Constituent System (CS), to fully interoperate in the context of a SoS. The majority of the existing systems were not designed to bepart of a SoS, interoperate in a instantaneous way, or maintain their operational independence despite their participation in oneor more SoS. Based on this context, the main contribution of this paper is to exploit how to design a software architecture for systems that are intended to become part of a SoS in the future. We conducted a software architecture design process to conceive a constituent architecture for Urban Mobility domain as CS. We evaluated the architecture by means of simulation. Preliminary results reveal that our proposal comply with the requirements raised during the architectural design process and can increase the possibility of a system to be a constituent of SoS.
D5.5 Commissioning
Creators: name: Ferriere, Alain
Publisher: name: Zenodo
Year: 2022

description: This document is the deliverable D5.5 of the project POLYPHEM. It is planned in the framework of the Work Package 5 (Manufacturing and installation of the prototype plant). The deliverable D5.5 reports on the commissioning of the components installed at Themis site as parts of the prototype plant POLYPHEM. These components are: the combustor, the recovery heat exchanger, the thermal oil piping, the ORC group and the thermal energy storage system. The solar receiver could not be delivered. The gas turbine has been commissioned at the test-bench of KAEFER in Bremen (Germany).
Refined Applications of the "Collapse of the Wavefunction"
Creators: name: Stodolsky, Leo
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In a two-part system the "collapse of the wavefunction" of one part can put the other part in a state which would be difficult or impossible to achieve otherwise, in particular one sensitive to small effects in the `collapse' interaction. We present some applications to the very symmeteric and experimentally accessible situations of the decays $ϕ(1020)\to K^oK^o$, $ψ(3770)\to D^oD^o$, or $Υ(4s)\to B^oB^o$, involving the internal state of the two-state $K^o$, $D^o$ or $B^o$ mesons. The "collapse of the wavefunction" occasioned by a decay of one member of the pair (`away side') fixes the state vector of that side's two-state system. Bose-Einstein statistics then determines the state of the recoiling meson (`near side'), whose evolution can then be followed further. In particular the statistics requirement dictates that the `away side' and `near side' internal states must be orthogonal at the time of the "collapse". Thus a CP violation in the `away side', decay implies a complementary CP impurity on the `near side', which can be detected in the further evolution. The CP violaion so manifested is necessarily direct CP violation, since neither the mass matrix nor time evolution was involved in the "collapse". A parametrization of the direct CP violation is given and various manifestations are presented. Certain rates or combination of rates are identified which are nonzero only if there is direct CP violation. The very explicit and detailed use made of "collapse of the wavefunction" makes the procedure interesting with respect to the fundamentals of quantum mechanics. We note an experimental consistency test for our treatment of the "collapse of the wavefunction", which can be carried out by a certain measurement of partial decay rates.
description: Twenty-four pages, no figures, further typos corrected, In section 6.4 `' direct CP violation for the flavor eigenstates' replaced by `flavor change for the flavor eigenstates'
Toward a Period-Specific Optimized Neural Network for OCR Error Correction of Historical Hebrew Texts
Creators: name: Suissa, Omri
name: Zhitomirsky-Geffet, Maayan
name: Elmalech, Avshalom
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Over the past few decades, large archives of paper-based historical documents, such as books and newspapers, have been digitized using the Optical Character Recognition (OCR) technology. Unfortunately, this broadly used technology is error-prone, especially when an OCRed document was written hundreds of years ago. Neural networks have shown great success in solving various text processing tasks, including OCR post-correction. The main disadvantage of using neural networks for historical corpora is the lack of sufficiently large training datasets they require to learn from, especially for morphologically-rich languages like Hebrew. Moreover, it is not clear what are the optimal structure and values of hyperparameters (predefined parameters) of neural networks for OCR error correction in Hebrew due to its unique features. Furthermore, languages change across genres and periods. These changes may affect the accuracy of OCR post-correction neural network models. To overcome these challenges, we developed a new multi-phase method for generating artificial training datasets with OCR errors and hyperparameters optimization for building an effective neural network for OCR post-correction in Hebrew.
title: Front Matter, Table of Contents, Preface, Conference Organization
Creators: name: Aldrich, Jonathan
name: Salvaneschi, Guido
Publisher: name: Schloss Dagstuhl – Leibniz-Zentrum für Informatik
Year: 2024
Subjects: subject: Front Matter
subject: Table of Contents
subject: Preface
subject: Conference Organization
subject: Software and its engineering → General programming languages

description: Front Matter, Table of Contents, Preface, Conference Organization
description: LIPIcs, Vol. 313, 38th European Conference on Object-Oriented Programming (ECOOP 2024), pages 0:i-0:xx
Additional file 1 of Bayesian spatial modelling of malaria burden in two contrasted eco-epidemiological facies in Benin (West Africa): call for localized interventions
Creators: name: Damien, Barikissou Georgia
name: Sode, Akoeugnigan Idelphonse
name: Bocossa, Daniel
name: Elanga-Ndille, Emmanuel
name: Aguemon, Badirou
name: Corbel, Vincent
name: Henry, Marie-Claire
name: Glèlè Kakaï, Romain Lucas
name: Remoué, Franck
Publisher: name: figshare
Year: 2022
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 1: Figure A1. Correlation between preselected covariates (c & d) and their similarity groups (a & b) for the OKT region (top panel) and DCO region (bottom panel) – Cells with crosses are correlation coefficients that are not statistically significant.
ESM 1
Creators: name: Stacey, Natasha
name: Gibson, Emily
name: Loneragan, Neil
name: Warren, Carol
name: Budy Wiryawan
name: Dedi Adhuri
name: Fitriana, Ria
Publisher: name: figshare
Year: 2019
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy

description: (DOCX 14Â kb)
RCT Study of the Colorado RESEA
Creators: name: Mueser, Peter
name: Poe-Yamagata, Eileen
name: Michaelides, Marios
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Social and Behavioral Sciences

description: This project will use a Randomized Control Trial (RCT) methodology to assess the effectiveness of the Colorado Reemployment Services and Eligibility Assessment (RESEA) program in reducing the dependence of UI claimants on UI benefits and improve their reemployment outcomes.
title: Hierarchy in the Early Helladic Peloponnese
Creators: name: Michael Smith, David
Publisher: name: University of Liverpool Repository
Year: 2023

description: The Early Helladic period in the Peloponnese (c. 3100 -2000 BC) is traditionally viewed as a phase of incipient hierarchical social organisation. This interpretation rests with a series of socio-economic developments perceived to represent an increased socio-economic complexity over that visible during the Late and Final Neolithic, including the appearance of organised, highly-socialised burial practices, a monumental architectural tradition, a non-uniform shift in Peloponnesian settlement patterns, the advent of sealing practices, an expansion of overland and maritime trade relationships and an increased visibility for metallurgical practice and Other specialist technologies. The second phase of the period, Early Helladic (E!"!) Il, and particularly so its later stages, is seen to represent a socio-cultural apex for the Early Helladic period and that for which the existence of elite groups on the Early Bronze Age Greek mainland -: has been most fervently proposed. There is a persistent belief that these dynamic multi-scale changes represent correlative developments articulated within a coherent and contemporary 'system' of social behaviours, within which social hierarchy was present from the start or out of which it quickly developed. Through the analysis of infant and adult burial practices, regional settlement activity and the use of monumental architecture in multiple modes of social interaction, this thesis demonstrates that a far more complex situation is evident. One in which systemic centralisation of 'elite' behaviours can be largely deconstructed in favour of temporally- and spatially-specific developments resulting from inter-group interaction or the particular geological, geographical or socio-political position of the study area. Increasingly accurate artefactual chronologies have allowed the identification of local and regional variation in behaviour which challenge existing ideas of 'hierarchy' and its operation in the Early Bronze Age Peloponnese, and suggests instead that the evident complexity of the period may find its origins in non-stratified communal and inter-communal action.
title: Micro- and Nanoplastic Analysis in Soils
Creators: name: Bigalke, Moritz
name: Filella, Montserrat
name: Fischer, Daniela
name: Muntwyler, Anna
name: Scheurer, Michael
name: Watts, Benjamin
Publisher: name: Swiss Chemical Society
Year: 2022

description: MP and NP particles in soils can be analyzed by wet chemical sample preparation, FTIR microscopy and STXM to investigate their occurrence and fate in the environment.
title: The Re-Production of Gender in Early Childhood Education: A Feminist New Materialist Analysis
Creators: name: Mallet, Rochelle
Publisher: name: The Open University
Year: 2025

description: This thesis is an ethnographic study of three Early Childhood Education settings in the East of England. It examines the ways that gender is produced and reproduced in these nursery settings. Participants included the infants and young children who attended the settings, the adults who worked there, and the environment itself. Drawing on feminist new materialism as a theoretical framework, a shift in focus towards the material world has informed how the research was designed, conducted, and analysed. This drew focus to the messiness and unpredictability of how gender manifests across and between the social and material world. Using diffractive analysis to de-centre the human, this thesis focuses on time and space, power, and the material world to examine how intra–acting networks of social and material entities reproduce gender. As a researcher I am implicated in these networks and contribute to the reproduction of gender. This thesis argues that gender is not a fixed and stable phenomenon which simply exists. Rather, concepts of gender are continuously generated through human and more-than-human relations which span across the social and material world. As such, gender does not always get reproduced in normative ways. Infants and young children are continuously negotiating their knowledge and understanding of the gendered self, gendered other, and the gendered material in ways that sometimes reshape human-social gender norms.
Extensions of set-theoretic solutions of the Yang-Baxter equation and a conjecture of Gateva-Ivanova
Creators: name: Vendramin, L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Algebra (math.QA)
subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: We develop a theory of extensions for involutive and nondegenerate solutions of the set-theoretic Yang-Baxter equation and use it to produce new families of solutions. As an application we construct an infinite family of counterexamples to a conjecture of Gateva-Ivanova related to the retractability of square-free solutions.
description: 12 pages
Additional file 2 of Bayesian spatial modelling of malaria burden in two contrasted eco-epidemiological facies in Benin (West Africa): call for localized interventions
Creators: name: Damien, Barikissou Georgia
name: Sode, Akoeugnigan Idelphonse
name: Bocossa, Daniel
name: Elanga-Ndille, Emmanuel
name: Aguemon, Badirou
name: Corbel, Vincent
name: Henry, Marie-Claire
name: Glèlè Kakaï, Romain Lucas
name: Remoué, Franck
Publisher: name: figshare
Year: 2022
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 2: Table A1. Simple binomial GLM fitted to the OKT data.
title: Molecular epidemiology of Giardia duodenalis
Creators: name: Taweenan, Weerapol
Publisher: name: University of Liverpool Repository
Year: 2023

description: Giardia duodenalis is a parasitic protozoan that affects the gastrointestinal tract, causing abdominal disorders of various animals and humans. To date, G. duodenalis has been genotypically divided into seven groups (assemblages), namely A to G, found in different host ranges. Whilst assemblages C to G are specific genotypes affecting restricted animal hosts, assemblages A and B parasitise both humans and a number of animal species, and have been considered as having zoonotic potential. The main objective of the current study was to investigate the molecular epidemiology of G. duodenalis in animals and humans in the UK. The current study also evaluated multilocus genotyping and determined the protein changes between assemblages A and B.
Mortality and losses to follow-up among adolescents living with HIV in the IeDEA global cohort collaboration
Creators: name: Penazzato, M.
name: Davies, M.-A.
name: Yotebieng, M.
name: IeDEA
name: Ayaya, S.
name: Vinikoor, M.
name: Machado, D.M.
name: Pinto, J.
name: Sohn, A.H.
name: McGowan, C.
name: Edmonds, A.
name: Malateste, K.
name: Leroy, V.
name: Kariminia, A.
name: Hazra, R.
name: Adedimeji, A., Albert Einstein College of Medicine, Bronx, NY, United States
name: Fairlie, L.
name: Takassi, E.
name: Law, M.
name: Vreeman, R.
name: Wools-Kaloustian, K.
Publisher: name: John Wiley and Sons Inc.
Year: 2018

description: Introduction: We assessed mortality and losses to follow-up (LTFU) during adolescence in routine care settings in the International epidemiology Databases to Evaluate AIDS (IeDEA) consortium. Methods: Cohorts in the Asia-Pacific, the Caribbean, Central, and South America, and sub-Saharan Africa (Central, East, Southern, West) contributed data, and included adolescents living with HIV (ALHIV) enrolled from January 2003 and aged 10 to 19 years (period of adolescence) while under care up to database closure (June 2016). Follow-up started at age 10 years or the first clinic visit, whichever was later. Entering care at <15 years was a proxy for perinatal infection, while entering care ≥15 years represented infection acquired during adolescence. Competing risk regression was used to assess associations with death and LTFU among those ever receiving triple-drug antiretroviral therapy (triple-ART). Results: Of the 61,242 ALHIV from 270 clinics in 34 countries included in the analysis, 69% (n = 42,138) entered care <15 years of age (53% female), and 31% (n = 19,104) entered care ≥15 years (81% female). During adolescence, 3.9% died, 30% were LTFU and 8.1% were transferred. For those with infection acquired perinatally versus during adolescence, the four-year cumulative incidences of mortality were 3.9% versus 5.4% and of LTFU were 26% versus 69% respectively (both p < 0.001). Overall, there were higher hazards of death for females (adjusted sub-hazard ratio (asHR) 1.19, 95% confidence interval (CI) 1.07 to 1.33), and those starting treatment at ≥5 years of age (highest asHR for age ≥15: 8.72, 95% CI 5.85 to 13.02), and in care in mostly urban (asHR 1.40, 95% CI 1.13 to 1.75) and mostly rural settings (asHR 1.39, 95% CI 1.03 to 1.87) compared to urban settings. Overall, higher hazards of LTFU were observed among females (asHR 1.12, 95% CI 1.07 to 1.17), and those starting treatment at age ≥5 years (highest asHR for age ≥15: 11.11, 95% CI 9.86 to 12.53), in care at district hospitals (asHR 1.27, 95% CI 1.18 to 1.37) or in rural settings (asHR 1.21, 95% CI 1.13 to 1.29), and starting triple-ART after 2006 (highest asHR for 2011 to 2016 1.84, 95% CI 1.71 to 1.99). Conclusions: Both mortality and LTFU were worse among those entering care at ≥15 years. ALHIV should be evaluated apart from younger children and adults to identify population-specific reasons for death and LTFU.
Maladaptive Avoidance and Fear Conditioning in Social Anxiety Disorder
Creators: name: Ball, Tali
name: Gross, James
Publisher: name: Open Science Framework
Year: 2020

description: This project aims to validate a novel virtual reality paradigm to objectively assess maladaptive avoidance in adults with social anxiety disorder, and to examine how maladaptive avoidance behavior relates to fear and safety learning. The project is funded by the Brain and Behavior Research Foundation’s NARSAD Young Investigator Award.
title: A multi-modal investigation of structural and functional neural bases of pitch discrimination in musicians and non-musicians
Creators: name: Salem  Alghamdi, Jamaan
Publisher: name: University of Liverpool Repository
Year: 2023

description: Musicians represent an ideal model for understanding experience-driven neuroplasticity in the human brain, especially in auditory and motor domains. Musicians exert intensive and durable practice of various multimodal skills (e.g., motor, auditory, visual and memory). It has been reported that certain regions of the adult musicians' brains are structurally larger than non- musicians. Also musicians demonstrate more sensitive pitch discrimination abilities compared to non-musicians because pitch labelling plays an important role in music. Music is made of a highly structured and complex succession of tones that arranged in a specific rhythm and played at specific pitch. In this thesis I aimed to; (1) Explore the influence of musical proficiency on pitch discrimination ability with investigating the laterality pitch discrimination ability and exploring some factors that could affect pitch discrimination ability such as aging, type of musical instrument and duration of musical proficiency. (2) Investigate anatomical plasticity of selected brain structures in musicians with exploring musical proficiency and the instrument type effect on sulcal and gyral topography. (3) Study the correlations between pitch discrimination performance and some cortical features of selected brain structures. (4) Investigate tonotopic mapping in the human auditory cortex using functional magnetic resonance imaging and (fMRI) and magneto encephalography (MEG). (5) Examine the influence of musical proficiency expertise on frequency organization and cortical activation of the human auditory cortex. Different structural methods were implemented to study differences between musicians and non-musicians in some structural features. FMRI and MEG were used to study tonotopic mapping in the human auditory cortex. During pitch discrimination tasks, musicians demonstrated more sensitivity than non-musicians. Musicians also showed significantly larger volume in various brain regions and shape differences in sulcal and gyral anatomy and the right hippocampus. Additionally, there were significant correlations between pitch discrimination performance and different structural measurements. Musicians had stronger BOLD fMRI in the medial and lateral part of the left HG. ANOVA tests of the amplitude of neuromagnetic N100 component showed a group effect of borderline significance. Results clearly show behavioural, structural and functional differences between these two groups. These results indicate that the morphology and neurophysiology of various brain regions and the pitch labelling have an essential role in musical proficiency.
Additional file 3 of Bayesian spatial modelling of malaria burden in two contrasted eco-epidemiological facies in Benin (West Africa): call for localized interventions
Creators: name: Damien, Barikissou Georgia
name: Sode, Akoeugnigan Idelphonse
name: Bocossa, Daniel
name: Elanga-Ndille, Emmanuel
name: Aguemon, Badirou
name: Corbel, Vincent
name: Henry, Marie-Claire
name: Glèlè Kakaï, Romain Lucas
name: Remoué, Franck
Publisher: name: figshare
Year: 2022
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 3: Table A2. Simple binomial GLM fitted to the DCO data.
title: Involvement of deubiquitinating enzymes in TGF[beta] receptor trafficking and signalling
Creators: name: Chojnowska-Monga, Monika
Publisher: name: University of Liverpool Repository
Year: 2023

description: The transforming growth factor-β (TGF β) superfamily of ligands controls a wide range of biological processes, including cellular differentiation, proliferation, motility, adhesion and apoptosis. It exerts its biological processes mainly through the TGF β receptor and downstream Smad proteins. Deregulation of TGF β signalling is associated with a variety of human diseases, including cancer. Ubiquitination is a reversible post-translational modification implicated In a variety of cellular processes, including proteasome-mediated protein degradation, DNA repair, regulation of transcription, endocytosis and receptor trafficking. Reversible ubiquitination tightly regulates the TGF β signaling pathway by controlling the basal expression level of TGF β pathway components, terminating signals after prolonged activation of signalling cascade or regulating activity of transcription factors involved in regulation of TGF β target gene expression. In this study, I assessed the involvement of two deubiquitinating enzymes (DUBs) AMSH (~ssociated molecule with the SH3 domain of STAM) and AMSH-LP (AMSH like protein) in the signalling of the TGF~ superfamily of ligands. I compared cellular localisation of both DUBs in HeLa cells as well as their relative protein levels in HEK293T cells. I performed a comparative analysis of the interactions of both AMSH and AMSH-LP with the components of the Smad family of signal transducers using a yeast two- hybrid approach. I also demonstrated evidence for the role of AMSH and AMSH-LP in the regulation of signalling by the TGF~ superfamily ligands, using a luciferase reporter driven by the TGF β or BMP-responsive promoters. Importantly, I showed differential dependence of AMSH and AMSH-LP effect on TGF~ signalling on their DUB activity. I then tested the importance of endosomal localisation for the role of AMSH and AMSH-LP in TGF β signalling and presented evidence for AMSH regulation of TGF β type I receptor levels. Finally, I report on a comprehensive siRNA screen testing the involvement of other DUBs in these signalling pathways.
Heterogeneous Population Dynamics and Scaling Laws near Epidemic Outbreaks
Creators: name: Widder, Andreas
name: Kuehn, Christian
Publisher: name: arXiv
Year: 2014
Subjects: subject: Dynamical Systems (math.DS)
subject: Classical Analysis and ODEs (math.CA)
subject: Pattern Formation and Solitons (nlin.PS)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: In this paper, we focus on the influence of heterogeneity and stochasticity of the population on the dynamical structure of a basic susceptible-infected-susceptible (SIS) model. First we prove that, upon a suitable mathematical reformulation of the basic reproduction number, the homogeneous system and the heterogeneous system exhibit a completely analogous global behaviour. Then we consider noise terms to incorporate the fluctuation effects and the random import of the disease into the population and analyse the influence of heterogeneity on warning signs for critical transitions (or tipping points). This theory shows that one may be able to anticipate whether a bifurcation point is close before it happens. We use numerical simulations of a stochastic fast-slow heterogeneous population SIS model and show various aspects of heterogeneity have crucial influences on the scaling laws that are used as early-warning signs for the homogeneous system. Thus, although the basic structural qualitative dynamical properties are the same for both systems, the quantitative features for epidemic prediction are expected to change and care has to be taken to interpret potential warning signs for disease outbreaks correctly.
description: 37 pages, 13 figures
Ciência Aberta: considerações para a pesquisa na área da enfermagem
Creators: name: Lima, Franciane Dantas de
name: Afonso, Drielle Cristina da Cruz Souza
name: Stutz, Evandro Toledo Gerhardt
name: Alencar, Simone de Menezes
Publisher: name: Zenodo
Year: 2022

description: Apresentação realizada na sessão O meu Póster em 40 segundos da 13ª Conferência Lusófona de Ciência Aberta, formato híbrido, de 10 a 12 de outubro de 2022.
Fermion-sign-free Majarana-quantum-Monte-Carlo studies of quantum critical phenomena of Dirac fermions in two dimensions
Creators: name: Li, Zi-Xiang
name: Jiang, Yi-Fan
name: Yao, Hong
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Quantum critical phenomena may be qualitatively different when massless Dirac fermions are present at criticality. Using our recently-discovered fermion-sign-free Majorana quantum Monte Carlo (MQMC) method introduced by us in Ref. [1], we investigate the quantum critical phenomena of {\it spinless} Dirac fermions at their charge-density-wave (CDW) phase transitions on the honeycomb lattice having $N_s=2L^2$ sites with largest $L=24$. By finite-size scaling, we accurately obtain critical exponents of this so-called Gross-Neveu chiral-Ising universality class of {\it two} (two-component) Dirac fermions in 2+1D: $η=0.45(2)$, $ν=0.77(3)$, and $β=0.60(3)$, which are qualitatively different from the mean-field results but are reasonably close to the ones obtained from renormalization group calculations.
description: 5.3 pages, Published as part of "Focus on Topological Physics: From Condensed Matter to Cold Atoms and Optics" in New Journal of Physics
title: Frequent subgraph mining algorithms on weighted graphs
Creators: name: Jiang, Chuntao
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis describes research work undertaken in the field of graph-based knowledge discovery (or graph mining). The objective of the research is to investigate the benefits that the concept of weighted frequent subgraph mining can offer in the context of the graph model based classification. Weighted subgraphs are graphs where some of the vertexes/edges are considered to be more significant than others. How to discover frequent sub-structures with different strengths is the main issue to be resolved in this thesis. The main approach to addressing this issue is to integrate weight constraints into the frequent subgraph mining process. It is suggested that the utilization of weighted frequent subgraph mining generates more discriminate and significant subgraphs, which will have application in, for example, the classification and clustering of graph data.
Models of support for disclosure of HIV status to HIV-infected children and adolescents in resource-limited settings
Creators: name: Leroy, V.
name: Arrivé, E.
name: Davies, M.-A.
name: Ayaya, S.
name: Vreeman, R.C.
name: Lelo, P.
name: Edmonds, A.
name: Duda, S.N.
name: Kouakou, K.
name: Razali, K.A.
name: the IeDEA Pediatric Working Group
name: Fong, S.M.
name: Chimbetete, C.
Publisher: name: John Wiley and Sons Inc.
Year: 2018

description: Introduction: Disclosure of HIV status to HIV-infected children and adolescents is a major care challenge. We describe current site characteristics related to disclosure of HIV status in resource-limited paediatric HIV care settings within the International Epidemiology Databases to Evaluate AIDS (IeDEA) consortium. Methods: An online site assessment survey was conducted across the paediatric HIV care sites within six global regions of IeDEA. A standardized questionnaire was administered to the sites through the REDCap platform. Results: From June 2014 to March 2015, all 180 sites of the IeDEA consortium in 31 countries completed the online survey: 57% were urban, 43% were health centres and 86% were integrated clinics (serving both adults and children). Almost all the sites (98%) reported offering disclosure counselling services. Disclosure counselling was most often provided by counsellors (87% of sites), but also by nurses (77%), physicians (74%), social workers (68%), or other clinicians (65%). It was offered to both caregivers and children in 92% of 177 sites with disclosure counselling. Disclosure resources and procedures varied across geographical regions. Most sites in each region reported performing staff members' training on disclosure (72% to 96% of sites per region), routinely collecting HIV disclosure status (50% to 91%) and involving caregivers in the disclosure process (71% to 100%). A disclosure protocol was available in 14% to 71% of sites. Among the 143 sites (79%) routinely collecting disclosure status process, the main collection method was by asking the caregiver or child (85%) about the child's knowledge of his/her HIV status. Frequency of disclosure status assessment was every three months in 63% of the sites, and 71% stored disclosure status data electronically. Conclusion: The majority of the sites reported offering disclosure counselling services, but educational and social support resources and capacities for data collection varied across regions. Paediatric HIV care sites worldwide still need specific staff members' training on disclosure, development and implementation of guidelines for HIV disclosure, and standardized data collection on this key issue to ensure the long-term health and wellbeing of HIV-infected youth.
title: Soil Contamination with Trace Metals: Quantification, Speciation, and Source Identification
Creators: name: Bigalke, Moritz
name: Schwab, Lorenz
name: Gygax, Sebastian
name: Mestrot, Adrien
Publisher: name: Swiss Chemical Society
Year: 2022

description: Developing new analytical techniques to measure heavy stable isotope ratios or to quantify the different species of trace metals present in the environment is essential to understand, ultimately prevent, and limit trace metal pollution in the environment.
Prediction of solar flares using neutrino detectors of the second generation
Creators: name: Boyarkin, Oleg
name: Boyarkina, Iren
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences
subject: F.2.2

description: The physics-based method of forecasting the high energy solar flares (SFs) with the help of the neutrino detectors utilizing the coherent elastic neutrino-nucleus scattering (CE$ν$NS) is considered. The behavior of the neutrino beams traveling through the coupled sunspots (CSs) being the sources of the future SFs is investigated. Two neutrino beams are included into consideration, namely, the $ν_{eL}$ beam and the $ν_{μL}$ beam which have been produced after the passage of the Micheev-Smirnov-Wolfenstein resonance. It is assumed that the neutrinos possess the charge radius, the magnetic and anapole moments while the CS magnetic field is vortex, nonhomogeneous and has twisting. Estimations of the weakening of the neutrino beams after traversing the resonant layers are given. It is demonstrated, that this weakening could be registered by the detectors employing CE$ν$NS only when the neutrinos have the Dirac nature.
description: 15 pages. arXiv admin note: substantial text overlap with arXiv:2301.08152
Additional file 4 of Bayesian spatial modelling of malaria burden in two contrasted eco-epidemiological facies in Benin (West Africa): call for localized interventions
Creators: name: Damien, Barikissou Georgia
name: Sode, Akoeugnigan Idelphonse
name: Bocossa, Daniel
name: Elanga-Ndille, Emmanuel
name: Aguemon, Badirou
name: Corbel, Vincent
name: Henry, Marie-Claire
name: Glèlè Kakaï, Romain Lucas
name: Remoué, Franck
Publisher: name: figshare
Year: 2022
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 4: Table A3. Bayesian binomial model with random noises fitted to the OKT data
D6.1 Measurement technique and experimental protocols for the testing and evaluation of the prototype of plant
Creators: name: Ferriere, Alain
name: Pithoud, Frédéric
Publisher: name: Zenodo
Year: 2022

description: This document is the deliverable D6.1 of the project POLYPHEM. The instrumentation is composed of sensors installed on the process at appropriated locations to measure the physical parameters which are relevant for the control of the plant and for the performance assessment. The sensors are connected to a data acquisition system capable of real time monitoring and recording of all data. The experimental protocols describe the operation parameters needed to validate the technology and assess the performance of each component and of the overall plant.
A residência de enfermagem para a qualidade do cuidado paliativo: revisão de escopo
Creators: name: Rithiely Rosa Feital Da Silva
name: De Andrade Silva, Rose Mary Costa Rosa
name: Pereira, Eliane Ramos
name: Janillê Luciana De Araújo
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Other Nursing
subject: Nursing
subject: FOS: Health sciences
subject: Medicine and Health Sciences
subject: Residência de Enfermagem
subject: Internship and Residency
subject: Residentes de Enfermería
subject: Residency, Nursing
subject: Nursing
subject: Residency
subject: Internato e Residência
subject: Palliative Care
subject: Residentes de Enfermagem
subject: Internato não Médico
subject: Internship, Nonmedical
subject: Internado y Residencia
subject: Residencia de Enfermería
subject: Cuidados Paliativos
subject: Residencia
subject: Internado no Médico
subject: Terminal Care
subject: Assistência Terminal
subject: Enfermagem
subject: Nursing Residents
subject: Cuidado Terminal
subject: Enfermería
subject: Residência

description: English title: The nursing residency for the quality of palliative care: scoping review. Objetivo da pesquisa: Mapear através da literatura científica fatores que dão subsídios a formação de residência de enfermagem para formar profissionais mais qualificados na atenção paliativa.
Sahara dust events over South-Western Bulgaria during the late spring of 2013
Creators: name: Tchorbadjieff, Assen
name: Christo Angelov
name: Arsov, Todor
name: Nikolova, Nina
name: Kalapov, Ivo
name: Boyadjieva, Aneta
Publisher: name: Figshare
Year: 2019
Subjects: subject: 40101 Atmospheric Aerosols
subject: FOS: Earth and related environmental sciences
subject: Atmospheric Sciences
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences

description: The Basic Environmental Observatory (BEO) at Moussala peak is the main site for permanent uninterrupted in-situ observations of atmospheric aerosol properties in south-eastern Europe. It is a region, which suffers a very severe
impact of Sahara dust storms due to a long-range air mass transport. Despite the large distance away from the southernmost part of the region, direct Sahara dust events (SDEs) are common for the BEO site, mainly during late winter and spring. Moreover, in many cases particles of Saharan origin have been detected over Moussala, mainly after a SDE occurring over central and south-eastern Europe. This paper reports seven events registered at Moussala BEO by a 3563 TSI Nephelometer during the period between April 1 and June 30, 2013. The impact is also estimated quantitatively of the mineral dust particles on the overall optical depth for the period reported.
Retention and mortality on antiretroviral therapy in sub-Saharan Africa: Collaborative analyses of HIV treatment programmes: Collaborative
Creators: name: Poda, A.
name: Vinikoor, M.
name: Niyongabo, T.
name: Zaniewski, E.
name: Dabis, F.
name: Egger, M.
name: Nash, D.
name: Adedimeji, A.A.
name: Tanon, A.
name: Anderegg, N.
name: Edmonds, A.
name: Fox, M.P.
name: Sinayobye, J.D.
name: Haas, A.D.
name: Ford, N.
name: Davies, M.-A.
Publisher: name: John Wiley and Sons Inc.
Year: 2018

description: Introduction: By 2020, 90% of all people diagnosed with HIV should receive long-term combination antiretroviral therapy (ART). In sub-Saharan Africa, this target is threatened by loss to follow-up in ART programmes. The proportion of people retained on ART long-term cannot be easily determined, because individuals classified as lost to follow-up, may have self-transferred to another HIV treatment programme, or may have died. We describe retention on ART in sub-Saharan Africa, first based on observed data as recorded in the clinic databases, and second adjusted for undocumented deaths and self-transfers. Methods: We analysed data from HIV-infected adults and children initiating ART between 2009 and 2014 at a sub-Saharan African HIV treatment programme participating in the International epidemiology Databases to Evaluate AIDS (IeDEA). We used the Kaplan-Meier method to calculate the cumulative incidence of retention on ART and the Aalen-Johansen method to calculate the cumulative incidences of death, loss to follow-up, and stopping ART. We used inverse probability weighting to adjust clinic data for undocumented mortality and self-transfer, based on estimates from a recent systematic review and meta-analysis. Results: We included 505,634 patients: 12,848 (2.5%) from Central Africa, 109,233 (21.6%) from East Africa, 347,343 (68.7%) from Southern Africa and 36,210 (7.2%) from West Africa. In crude analyses of observed clinic data, 52.1% of patients were retained on ART, 41.8% were lost to follow-up and 6.0% had died 5 years after ART initiation. After accounting for undocumented deaths and self-transfers, we estimated that 66.6% of patients were retained on ART, 18.8% had stopped ART and 14.7% had died at 5 years. Conclusions: Improving long-term retention on ART will be crucial to attaining the 90% on ART target. Naïve analyses of HIV cohort studies, which do not account for undocumented mortality and self-transfer of patients, may severely underestimate both mortality and retention on ART.
Topic-adjusted visibility metric for scientific articles
Creators: name: Tan, Linda S. L.
name: Chan, Aik Hui
name: Zheng, Tian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Measuring the impact of scientific articles is important for evaluating the research output of individual scientists, academic institutions and journals. While citations are raw data for constructing impact measures, there exist biases and potential issues if factors affecting citation patterns are not properly accounted for. In this work, we address the problem of field variation and introduce an article level metric useful for evaluating individual articles' visibility. This measure derives from joint probabilistic modeling of the content in the articles and the citations amongst them using latent Dirichlet allocation (LDA) and the mixed membership stochastic blockmodel (MMSB). Our proposed model provides a visibility metric for individual articles adjusted for field variation in citation rates, a structural understanding of citation behavior in different fields, and article recommendations which take into account article visibility and citation patterns. We develop an efficient algorithm for model fitting using variational methods. To scale up to large networks, we develop an online variant using stochastic gradient methods and case-control likelihood approximation. We apply our methods to the benchmark KDD Cup 2003 dataset with approximately 30,000 high energy physics papers.