cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
sj-pdf-1-asp-10.1177_0003702820949928 - Supplemental material for Behind the Scene of “The Holy Family with St. Anne and the Young St. John” by Bernardino Luini: A Computer-Assisted Method to Unveil the Underdrawings
Creators: name: Caccia, Michele
name: Bonizzoni, Letizia
name: Martini, Marco
name: Fontana, Raffaella
name: Villa, Valeria
name: Galli, Anna
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, sj-pdf-1-asp-10.1177_0003702820949928 for Behind the Scene of “The Holy Family with St. Anne and the Young St. John” by Bernardino Luini: A Computer-Assisted Method to Unveil the Underdrawings by Michele Caccia, Letizia Bonizzoni, Marco Martini, Raffaella Fontana, Valeria Villa and Anna Galli in Applied Spectroscopy
NIV@Home: a pilot randomized controlled trial of in-home noninvasive ventilation initiation compared to a single-day admission model
Creators: name: Sheers, Nicole L.
name: Hannan, Liam M.
name: Rautela, Linda
name: Graco, Marnie
name: Jones, Jennifer
name: Retica, Sarah
name: Saravanan, Krisha
name: Burgess, Nicola
name: McGaw, Rebekah
name: Donovan, Ashleigh
name: Clohessy, Talia
name: Chao, Caroline
name: Charles, Cameron
name: Howard, Mark E.
name: Berlowitz, David J.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Objective: Noninvasive ventilation (NIV) is the primary treatment for respiratory insufficiency in neuromuscular disease. NIV implementation is usually conducted within hospitals; however, in-home implementation with intensive follow-up is an effective alternative. This pilot study aimed to assess model feasibility, acceptability, and NIV usage at 12-weeks after a single visit in-home implementation of NIV with remote monitoring follow-up (NIV@Home) compared to an in-hospital day admission NIV initiation plus planned polysomnography (Usual care). Methods: A single-blinded randomized controlled trial (www.anzctr.org.au ACTRN12620000682943) of adults with neuromuscular disease referred for NIV implementation. Participants were stratified by disease (MND or Other diagnoses) and bulbar symptoms before randomization to NIV@Home or Usual care, with follow-up at 12-weeks. The primary outcome was NIV usage. Secondary outcomes included feasibility, health-related quality of life, symptoms, carer burden, and NIV experience (semi-structured qualitative interviews). Results: Twenty-three participants (MND bulbar = 9, MND non-bulbar = 11, Other = 3) were randomized (NIV@Home = 9). No statistical differences were observed in the percentage of MND participants using NIV for >4 hours/day (NIV@Home = 33% vs. Usual care = 60%, p = 0.370), average use (NIV@Home = 2.4 [1.5–9.3] vs. 5.3 [1.8–7.0] hours/day, p = 0.568), or secondary outcomes. In-home NIV implementation was feasible and safe but took more therapist time (NIV@Home = 278 [270–305] vs. 172 [130–200] minutes, p < 0.001). Participants in the NIV@Home group reported substantial advantages to receiving care in home. Conclusion: In-home NIV implementation is feasible and acceptable to people with MND but requires more therapist time. Larger studies are required to determine whether there are clinically important differences between this model of NIV initiation and a traditional hospital-based model.
Estimating the minimum important difference in the ALSFRS-R-instrument in people living with MND
Creators: name: Boddy, Sarah L.
name: Simpson, Rebecca M.
name: Walters, Stephen J.
name: Bamford, Hannah
name: Walsh, Theresa
name: McDermott, Christopher J.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Objective: The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) is a commonly used outcome measure in clinical trials for motor neuron disease (MND) therapies. As such, understanding how differences in scores relate to patient perception of their disease status is important when interpreting ALSFRS-R data. Our study sought to estimate the minimal important difference (MID) for the ALSFRS-R, the smallest difference in scores at which patients perceive a change in their quality of life. Methods: Data were collected as part of a longitudinal, observational saliva management study, ProSec3. These included both the ALSFRS-R and a global rating of change question (GRoC), which asked participants to rate how their disease had progressed since the previous visit. Anchor-based and distribution-based methods have been used to estimate the MID of the ALSFRS-R. The MID was estimated using two methods of calculating the total ALSFRS-R score, the original summation scale method and the recently proposed interval scale method. Results: A total of 145 people with MND had longitudinal ALSFRS-R and GRoC data. Different methods estimated the ALSFRS-R MID to be in the range of 2.02–5.43 for the summation scale and 1.23–3.31 for the interval scale method over a 3-month period, the time between study visits. Using anchor-based methods our MID estimates for the ALSFRS-R are 3.8 points and 2 points, respectively. Conclusions: The results of this study can guide clinicians and researchers in the interpretation of ALSFRS-R data. However, further studies are required to more precisely estimate the ALSFRS-R MID.
Additional file 1 of Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion
Creators: name: Wojtowicz, Edyta E.
name: Mistry, Jayna J.
name: Uzun, Vladimir
name: Hellmich, Charlotte
name: Scoones, Anita
name: Chin, Desmond W.
name: Kettyle, Laura M.
name: Grasso, Francesca
name: Lord, Allegra M.
name: Wright, David J.
name: Etherington, Graham J.
name: Woll, Petter S.
name: Belderbos, Mirjam E.
name: Bowles, Kristian M.
name: Nerlov, Claus
name: Haerty, Wilfried
name: Bystrykh, Leonid V.
name: Jacobsen, Sten Eirik W.
name: Rushworth, Stuart A.
name: Macaulay, Iain C.
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1. Correlation between barcode counts recovered from cDNA or gDNA. 1. Correlation between normalized read count recovered from cDNA and gDNA in single clones. Obtained raw reads in each sample were normalized per 1000 and plotted. 2. Assessment of cDNA and gDNA linear correlation using 3 barcoded clones depicted in panel A. The Pearson correlation coefficient is r=0.85. A pseudocount of 0.001 is used to plot non detected clones in gDNA samples. 3. Scatter plot showing the normalised barcode read count recovered from cDNAor gDNAfrom the same unequally mixed sample, included 2 technical replicates.
Neurologists’ understanding of reproductive medicine options for genetic forms of motor neuron disease
Creators: name: Allen, Shanice
name: Howard, Jade
name: Mcdermott, Christopher J
name: Boardman, Felicity
name: Mcneill, Alisdair
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: To examine the knowledge, confidence and practice of motor neuron disease (MND) clinicians toward discussing reproductive options with people who carry a causal variant in an MND gene (both clinically affected and asymptomatic). An online cross-sectional survey was distributed nationwide to UK MND clinicians and clinical geneticists and genetic counselors. The survey assessed respondents’ understanding on reproductive medicine techniques; their confidence in discussing reproductive medicine options and their access to information resources. Seventy six clinicians responded to the online survey (45 neurology clinicians and 31 clinical geneticists). MND clinicians had limited knowledge and low confidence in discussing reproductive medicine options. Geneticists were more likely to carry out reproductive genetic counseling with very few MND clinicians reporting undertaking these discussions. Further, 57% of the 45 MND clinicians surveyed reported to have never made a referral for reproductive genetic counseling. Multiple barriers to offering reproductive counseling or referral were identified including a lack of knowledge, lack of awareness of the different options, lack of clinic time and uncertainty around issues such as funding for PGT and whose responsibility it comes under. There is a need for training and education on reproductive options and referral for these options needs to be integrated within the health system. Developing more resources for both clinicians and patients is required as MND clinicians reported a lack of resources.
sj-pdf-1-asp-10.1177_0003702820949129 - Supplemental material for Vibrational Spectroscopic Monitoring of the Gelation Transition in Nafion Ionomer Dispersions
Creators: name: Liang, Ying
name: Kitt, Jay P.
name: Minteer, Shelley D.
name: Harris, Joel M.
name: Korzeniewski, Carol
Publisher: name: SAGE Journals
Year: 2020
Subjects: Engineering not elsewhere classified

description: Supplemental material, sj-pdf-1-asp-10.1177_0003702820949129 for Vibrational Spectroscopic Monitoring of the Gelation Transition in Nafion Ionomer Dispersions by Ying Liang, Jay P. Kitt, Shelley D. Minteer, Joel M. Harris and Carol Korzeniewski in Applied Spectroscopy
Supp_Appendix_B – Supplemental material for Learning From Science News via Interactive and Animated Data Visualizations: An Investigation Combining Eye Tracking, Online Survey, and Cued Retrospective Reporting
Creators: name: Greussing, Esther
name: Kessler, Sabrina Heike
name: Boomgaarden, Hajo G.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Science Policy

description: Supplemental material, Supp_Appendix_B for Learning From Science News via Interactive and Animated Data Visualizations: An Investigation Combining Eye Tracking, Online Survey, and Cued Retrospective Reporting by Esther Greussing, Sabrina Heike Kessler and Hajo G. Boomgaarden in Science Communication
Additional file 8 of Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion
Creators: name: Wojtowicz, Edyta E.
name: Mistry, Jayna J.
name: Uzun, Vladimir
name: Hellmich, Charlotte
name: Scoones, Anita
name: Chin, Desmond W.
name: Kettyle, Laura M.
name: Grasso, Francesca
name: Lord, Allegra M.
name: Wright, David J.
name: Etherington, Graham J.
name: Woll, Petter S.
name: Belderbos, Mirjam E.
name: Bowles, Kristian M.
name: Nerlov, Claus
name: Haerty, Wilfried
name: Bystrykh, Leonid V.
name: Jacobsen, Sten Eirik W.
name: Rushworth, Stuart A.
name: Macaulay, Iain C.
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8: Fig. S4. Gating strategy for FACS purification of transduced progenitors and stem cells, summary of single cell RNA sequencing including average read count, gene count and marker genes annotating cell clusters. A. Gating strategy for FACS-purification of single BM populations: LT-HSC, CFU-E and MkP, which were sorted as GFP+. B. Violin plots showing the distribution of read count per cell, number of genes per single cell and fraction of mitochondrial genes in single cells within 3 analysed BM populations C. UMAP plot representing computationally assigned clusters of cells based on their transcriptomes (Seurat clusters). D. UMAP plot representing 3 clusters of cells split by their FACS phenotype. E. UMAP plots representing the expression of marker genes for LT-HSC (Procr, Slamf1, CD48, Mpl, Selp), MkP (Mpl, Slamf1, Selp) and CFU-E (Hba-a1, Slc25a21).
Author_Response – Supplemental material for Early predictors for mechanical ventilation in COVID-19 patients
Creators: name: Li, Wen
name: Lin, Fengyu
name: Dai, Minhui
name: Chen, Lingli
name: Han, Duoduo
name: Cui, Yanhui
name: Pan, Pinhua
Publisher: name: SAGE Journals
Year: 2020
Subjects: Aged Health Care
Pharmacology and Pharmaceutical Sciences not elsewhere classified
Respiratory Diseases

description: Supplemental material, Author_Response for Early predictors for mechanical ventilation in COVID-19 patients by Wen Li, Fengyu Lin, Minhui Dai, Lingli Chen, Duoduo Han, Yanhui Cui and Pinhua Pan in Therapeutic Advances in Respiratory Disease
Can resting lung function predict the response of a person living with motor neuron disease to a hypoxic challenge test?
Creators: name: Clohessy, Talia A.
name: Sheers, Nicole L.
name: Berlowitz, David J.
name: Ruehland, Warren R.
name: Brazzale, Danny J.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: People living with MND (PlwMND) are at risk of altitude-related hypoxia during flight. The Hypoxic Challenge Test (HCT) determines whether in-flight oxygen is required but can be expensive and inaccessible. To assist with travel recommendations, we investigated the relationship between altitude simulation-induced hypoxemia and baseline lung function. Retrospective audit of clinical database of PlwMND who had HCT and lung function. Pearson’s correlation assessed relationships between oxygen saturation at altitude (AltSpO2) and lung function. Univariate logistic regression analysis and receiver operator characteristic (ROC) curves determined associations between lung function and HCT pass or fail. Between 2004–2023, 50 PlwMND were identified (median (IQR) diagnosis to HCT = 11.6 (16.9) months, mean ± SD forced vital capacity (FVC) = 2.4 ± 0.9 liters). Ten patients dropped below 85% SpO2 during testing (HCT fail). Baseline SpO2 was associated with AltSpO2 (r = 0.64) and predicted HCT pass or fail (OR 2.0 [95% CI 1.2–3.4], area under ROC curve (AUC) =0.8 [0.6–1.0]), as did FVC (AUC = 0.8 [0.6–0.9]). PlwMND with a FVC > 2.7L or a resting SpO2 > 97% are likely to pass HCT, whereas all those with FVC < 1L and SpO2 < 92% failed. PlwMND with FVC >2.7L or SpO2 >97% are unlikely to require oxygen or ventilatory supports for airline travel. A FVC below 2.7L will require a HCT to confidently determine HCT outcome, with testing still required for FVC <1L or baseline SpO2 <92%, to provide evidence to the airlines for in-flight respiratory support.
sj-pdf-1-chi-10.1177_1742395320959422 - Supplemental material for The prevalence and management of diabetes among Vietnamese Americans: A population-based survey of an understudied ethnic group
Creators: name: Souza, Leanne R De
name: Chan, Keith T
name: Kobayashi, Karen
name: Karasiuk, Alexis
name: Fuller-Thomson, Esme
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111702 Aged Health Care
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-chi-10.1177_1742395320959422 for The prevalence and management of diabetes among Vietnamese Americans: A population-based survey of an understudied ethnic group by Leanne R De Souza, Keith T Chan, Karen Kobayashi, Alexis Karasiuk and Esme Fuller-Thomson in Chronic Illness
Appendix – Supplemental material for Berberine for diarrhea in children and adults: a systematic review and meta-analysis
Creators: name: Yu, Mingkun
name: Jin, Xuejing
name: Liang, Changhao
name: Bu, Fanlong
name: Pan, Deng
name: He, Qian
name: Ming, Yang
name: Little, Paul
name: Du, Hongbo
name: Liang, Shibing
name: Hu, Ruixue
name: Li, Chengze
name: Hu, Yanhong Jessika
name: Cao, Huijuan
name: Liu, Jianping
name: Fei, Yutong
Publisher: name: SAGE Journals
Year: 2020
Subjects: Nutrition and Dietetics not elsewhere classified
Oncology and Carcinogenesis not elsewhere classified
Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, Appendix for Berberine for diarrhea in children and adults: a systematic review and meta-analysis by Mingkun Yu, Xuejing Jin, Changhao Liang, Fanlong Bu, Deng Pan, Qian He, Yang Ming, Paul Little, Hongbo Du, Shibing Liang, Ruixue Hu, Chengze Li, Yanhong Jessika Hu, Huijuan Cao, Jianping Liu and Yutong Fei in Therapeutic Advances in Gastroenterology
Exploring the role of anthropometric measurements to assess nutritional status in amyotrophic lateral sclerosis: a longitudinal prospective cohort study
Creators: name: Roscoe, Sarah
name: Allen, Scott P.
name: McDermott, Christopher
name: Stavroulakis, Theocharis
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: To observe longitudinal correlations between limb anthropometry against weight, BMI and functional decline in patients with amyotrophic lateral sclerosis. A longitudinal, prospective, cohort study was undertaken. Four consecutive measurements of weight, height, triceps skinfold thickness (TSF), mid-upper arm (MUAC) and calf circumferences were collected at three-monthly intervals. Fat- and lean body mass were estimated using measurements of TSF and derivations of arm muscle area, respectively. Correlation analyses indicated associations between anthropometric assessments and functional decline (ALSFRS-R). Longitudinal changes were assessed using repeated measures analyses. Data from 18 participants was analyzed. At enrollment, weight positively correlated with MUAC (n = 17, p = 0.0001), arm muscle area (n = 17, p = 0.04) and calf circumference (n = 17, p < 0.0001). The ALSFRS-R score negatively correlated with weight (n = 17, p = 0.03), MUAC (n = 18, p = 0.01), TSF (n = 18, p = 0.04), and calf circumference (n = 18, p = 0.003). Function significantly declined by a difference of 6.3 points per month (p = 0.009). A positive correlation was observed between the changes in weight and calf circumference over nine months (r = 0.70, p = 0.02, n = 10). Limb anthropometric measurements may be surrogate indicators of weight and BMI; TSF may be a practical, reliable indicator of fat mass, whilst changes in calf circumference may be alternatively used to monitor changes in nutritional status in the clinic.
Enago-Certificate-YASLKJ-3. – Supplemental material for Midterm Outcomes of Autologous Osteochondral Graft Transplantation Only in the Femoral Condyle without Treating the Tibial Plateau with Subchondral Bone Exposed
Creators: name: Nakagawa, Yasuaki
name: Mukai, Shogo
name: Maeda, Takahiro
name: Akamatsu, Shota
name: Satomi, Kentaro
name: Nakamura, Ryota
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, Enago-Certificate-YASLKJ-3. for Midterm Outcomes of Autologous Osteochondral Graft Transplantation Only in the Femoral Condyle without Treating the Tibial Plateau with Subchondral Bone Exposed by Yasuaki Nakagawa, Shogo Mukai, Takahiro Maeda, Shota Akamatsu, Kentaro Satomi and Ryota Nakamura in CARTILAGE
10.1177_0309364620956868_Supplementary_Material – Supplemental material for Evaluation of a passive pediatric leg exoskeleton during gait
Creators: name: Zistatsis, Jessica
name: Peters, Keshia M
name: Ballesteros, Daniel
name: Feldner, Heather A
name: Bjornson, Kristie
name: Steele, Katherine M
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, 10.1177_0309364620956868_Supplementary_Material for Evaluation of a passive pediatric leg exoskeleton during gait by Jessica Zistatsis, Keshia M Peters, Daniel Ballesteros, Heather A Feldner, Kristie Bjornson and Katherine M Steele in Prosthetics and Orthotics International
Supplementary Material 1 - Supplemental material for Two New Geranylated Biphenyl Esters From Artocarpus altilis
Creators: name: Yitong Zhang
name: Xinghua Jin
name: Arancon, Norman Q.
name: Borris, Robert P.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, Supplementary Material 1, for Two New Geranylated Biphenyl Esters From Artocarpus altilis by Yitong Zhang, Xinghua Jin, Norman Q. Arancon and Robert P. Borris in Natural Product Communications
Spanish adaptation of the Rasch-Built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS)
Creators: name: Cadavid, Javier Mascías
name: Radakovic, Ratko
name: Radakovic, Chelsea
name: Benito, Yolanda Moran
name: Esteban, Saúl Marín
name: Rodríguez-Santos, Francisco
name: Campos, Teresa Salas
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Amyotrophic lateral sclerosis (ALS) is characterized functional decline, traditionally measured by the ALS Functional Rating Scale-Revised (ALSFRS-R). The Rasch-Built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS) is an alternative comprehensive, detailed functional disability measure for people with ALS (pwALS), not yet translated to Spanish. The aim of this study was to translate and validate the Spanish ROADS. 53 Spanish speaking pwALS were recruited. They completed the ALSFRS-R and Spanish ROADS. Reliability (internal consistency, intra-class correlation) and validity (ALSFRS-R total and item-total correlations) were determined. The Spanish ROADS internal consistency reliability was excellent (Cronbach’s standardized alpha = 0.94), the test-retest reliability intra-class correlation value was 0.93. There was a strong significant correlation between the Spanish ROADS and ALSFRS-R totals (rs(52) = .89, p < .001). Additionally, the ALSFRS-R subscales and ROADS items correlations showed domain-to-item specific expected significant correlations. The Spanish ROADS is a psychometrically robust, valid and reliable measure for quantifying functional disability for pwALS.
Determinants and progression of stigma in amyotrophic lateral sclerosis/motor neuron disease
Creators: name: Young, Carolyn A.
name: Chaouch, Amina
name: Mcdermott, Christopher J.
name: Al-Chalabi, Ammar
name: Chhetri, Suresh K.
name: Bidder, Caroline
name: Edmonds, Elizabeth
name: Ellis, Cathy
name: Annadale, Joe
name: Wilde, Lisa
name: Sharrack, Basil
name: Malaspina, Andrea
name: Leach, Oliver
name: Mills, Roger
name: Tennant, Alan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Neuroscience
Biological Sciences not elsewhere classified
Science Policy

description: Objective: Stigma in amyotrophic lateral sclerosis/motor neurone disease (ALS/MND) may be felt or enacted; felt stigma covers feeling devalued by the illness, whereas enacted stigma refers to being treated differently because of it. Stigma in ALS/MND has been shown to increase social withdrawal, worsen quality of life, and reduce use of assistive devices, so we explored prevalence and factors influencing stigma. Methods: Participants in the Trajectories of Outcome in Neurological Conditions-ALS study completed scales measuring stigma, fatigue, spasticity, functioning, mood, worry, self-esteem, and perceived health, as well as demographic information and symptoms like head drop or emotional lability. Following transformation to interval-scale estimates, data were analyzed by regression, structural equation modeling, and trajectory models. Results: Stigma was experienced by 83.5% of 1059 respondents. Worry, disease severity (King’s stage ≥ 3), emotional lability, fatigue, spasticity, and bulbar onset increase stigma. In contrast, increasing age, living with spouse/partner, and greater self-esteem were associated with reduced stigma. Trajectory analysis over 30 months (N = 1049) showed three groups, the largest (70.2%) had high levels of stigma which significantly increased during follow-up. In a recently diagnosed subset of 347 participants, stigma was experienced early in the disease course (<7 months after diagnosis), and for 77.2% stigma significantly increased over time. Conclusions: Both felt and enacted stigma are frequently perceived by people living with ALS/MND. Younger people and those with bulbar onset, emotional lability, worry, fatigue, and spasticity, or at more advanced clinical stages, are at greater risk.
sj-pdf-2-lup-10.1177_0961203320966378 - Supplemental material for Improving sensitivity of the connective tissue disease screening questionnaire: A comparative study of various scoring methods
Creators: name: Xiang, Ling
name: Low, Andrea Hsiu Ling
name: Leung, Ying Ying
name: Fong, Warren
name: Mihir Gandhi
name: Xiaohui Xin
name: Uy, Elenore JB
name: Sparks, Jeffrey A
name: Karlson, Elizabeth W
name: Thumboo, Julian
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-2-lup-10.1177_0961203320966378 for Improving sensitivity of the connective tissue disease screening questionnaire: A comparative study of various scoring methods by Ling Xiang, Andrea Hsiu Ling Low, Ying Ying Leung, Warren Fong, Mihir Gandhi, Xiaohui Xin, Elenore JB Uy, Jeffrey A Sparks, Elizabeth W Karlson and Julian Thumboo in Lupus
4D_manometry_appendix_supplement – Supplemental material for Four-dimensional impedance manometry derived from esophageal high-resolution impedance-manometry studies: a novel analysis paradigm
Creators: name: Wenjun Kou
name: Carlson, Dustin A.
name: Neelesh A. Patankar
name: Kahrilas, Peter J.
name: Pandolfino, John E.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, 4D_manometry_appendix_supplement for Four-dimensional impedance manometry derived from esophageal high-resolution impedance-manometry studies: a novel analysis paradigm by Wenjun Kou, Dustin A. Carlson, Neelesh A. Patankar, Peter J. Kahrilas and John E. Pandolfino in Therapeutic Advances in Gastroenterology
Supplementary_file.2.doc – Supplemental material for A systematic review of randomized controlled trials of psychoeducation interventions for patients diagnosed with schizophrenia
Creators: name: Alhadidi, Majdi MB
name: Khatijah Lim Abdullah
name: Yoong, Tang Li
name: Lourance Al Hadid
name: Danaee, Mahmoud
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine

description: Supplemental material, Supplementary_file.2.doc for A systematic review of randomized controlled trials of psychoeducation interventions for patients diagnosed with schizophrenia by Majdi MB Alhadidi, Khatijah Lim Abdullah, Tang Li Yoong, Lourance Al Hadid and Mahmoud Danaee in International Journal of Social Psychiatry
Mucius, Alexander, Datysus and Chindeus, martyrs with healing power, mentioned by Victricius of Rouen
Creators: name: Admin, CSLA
Publisher: name: University of Oxford
Year: 2015
Subjects: History

description: All evidence related to Mucius, Alexander, Datysus and Chindeus, martyrs with healing power, mentioned by Victricius of Rouen.
Supplementary Material
Creators: name: Ellis, Sarah L H
name: Rodan, Ilona
name: Carney, Hazel C
name: Heath, Sarah
name: Rochlitz, Irene
name: Shearburn, Lorinda D
name: Sundahl, Eliza
name: Westropp, Jodi L
Publisher: name: SAGE Journals
Year: 2020
Subjects: Veterinary Medicine

description: Portuguese version of the Guidelines
Pers_and_Ret_Supplement_JAH2 – Supplemental Material for Personality, Retirement, and Cognitive Impairment: Moderating and Mediating Associations
Creators: name: Strickhouser, Jason E.
name: Sutin, Angelina R.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, Pers_and_Ret_Supplement_JAH2 for Personality, Retirement, and Cognitive Impairment: Moderating and Mediating Associations by Jason E. Strickhouser and Angelina R. Sutin in Journal of Aging and Health
Supplementary_material – Supplemental material for Occupational stress measures of tenure-track librarians
Creators: name: Cameron, Laura
name: Pierce, Stephanie
name: Conroy, Julia
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Supplemental material, Supplementary_material for Occupational stress measures of tenure-track librarians by Laura Cameron, Stephanie Pierce and Julia Conroy in Journal of Librarianship and Information Science
Ragota, Leonida, Anastasia and Anatoclia, martyrs with healing powers, mentioned by Victricius of Rouen
Creators: name: Admin, CSLA
Publisher: name: University of Oxford
Year: 2015
Subjects: History

description: All evidence related to Ragota, Leonida, Anastasia and Anatoclia, martyrs with healing powers, mentioned by Victricius of Rouen .
Semantic behavioral variant frontotemporal dementia and semantic dementia associated with TARDBP mutations
Creators: name: Piga, Giuseppe
name: Fadda, Laura
name: Borghero, Giuseppe
name: Maccabeo, Alessandra
name: Pala, Francesca
name: Murru, Maria Rita
name: Giglio, Sabrina
name: Puligheddu, Monica
name: Floris, Gianluca
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Frontotemporal dementia (FTD) is a highly heritable group of neurodegenerative disorders, characterized by varying clinical and pathological features. TARDBP gene has been described worldwide within the FTD/ALS spectrum but its association with right and left temporal variant of FTD (tvFTD) is still unclear. This study aimed to reclassify a Sardinian FTD cohort according to proposed criteria for the semantic behavioral variant FTD (sbvFTD), explore TARDBP mutations’ association with tvFTD, and review related literature. From our FTD cohort of 94 patients, ten fulfilled the criteria for sbvFTD. Therefore, in light of the diagnostic reclassification carried out, we describe the largest series of unrelated patients with TARDBP p.A382T missense mutation, including four new cases of tvFTD: two sbvFTD and two svPPA, exhibiting semantic and behavioral disorders and showing predominant right and left anterior temporal lobe involvement, respectively. We present for the first time two sbvFTD cases carrying the pA382T TARDBP mutation. Comparison with C9orf72 and non-mutated patients revealed lower age at onset (p = 0.006), and a higher prevalence of tvFTD, particularly sbvFTD (p < 0.001), and motor neuron disease in TARDBP carriers (p < 0.001). Our findings along with a review of the literature highlighted TARDBP mutations’ association with sbvFTD and semantic dementia, suggesting a genetic role in temporal variants of FTD and emphasizing the need for TARDBP mutation screening in these cases. Reclassifying FTD cohorts, including the sbvFTD phenotype, could aid in better defining the clinical spectrum of tvFTD and guide differential diagnosis across different FTD populations with TARDBP or other FTD-related mutations.
Associations between water exposure and the development of amyotrophic lateral sclerosis: a matched case-control study
Creators: name: Saucier, Daniel
name: Bélanger, Mathieu
name: Liu, Zikuan
name: Lavigne, Eric
name: O’Connell, Colleen
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Previous studies have hinted at an association between water exposure and the development of ALS. However, proximity measures to these water sources have been limited to questionnaires or large buffers due to a lack of fine geospatial measures. They also do not distinguish the various classes of hydrographic features. Thus, we created a robust database to investigate the association between proximity to water bodies at place of residence and the development of ALS. A matched (sex and year of birth) case-control study was conducted in New Brunswick, Canada from January 2003 to February 2021. Study population included 304 ALS patients and 1207 controls with their historical postal codes linked to spatial proximity datasets and air pollution index indicators (proxy measures for contamination by run-off). Odds of ALS were not significantly associated with proximity to water bodies, even within a 250 m buffer from place of residence (Oceans: 1.10, 0.60–2.00 [95% CI], Reservoirs/Ponds/Lakes: 1.24, 0.47–3.30 [95% CI]). As for interaction models investigating proximity to potentially contaminated water bodies, none of the final fitted models observed an association between proximity to water bodies with indicators of potential run-off sources and the development of ALS. No significant association between proximity to water bodies at place of residence and the development of ALS were observed in the current study. Future studies should consider taking direct measurements of water quality or utilize geomaps of spraying activities and cyanobacteria blooms alongside proximity measures. Household water quality is another avenue to explore, particularly well water use.
Care trajectories and adherence to respiratory management recommendations in persons living with amyotrophic lateral sclerosis: a ten-year cohort study in a French tertiary university centre
Creators: name: Tankéré, Pierre
name: Cascarano, Estelle
name: Raymond, Christel Saint
name: Mallaret, Martial
name: Ruiz, Cristina Toribio
name: Herquelot, Eléonore
name: Denis, Helene
name: Maurette, Mallory Cals
name: Tamisier, Renaud
name: Pépin, Jean Louis
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Virology

description: Objective: This study determined real-life care trajectories before and after initiation of noninvasive ventilation (NIV) in patients with amyotrophic lateral sclerosis (ALS). Caregiver adherence to respiratory management recommendations and the associated survival rate of people with ALS were also assessed. Methods: Data were obtained from a tertiary center prospective ALS database that included 10 years of follow-up data for people with ALS. Results are presented numerically and with graphical time sequence analysis through K clustering (TAK) representation. Kaplan Meier and Cox models were used to determine survival and associated prognostic factors. Results: 109 patients with ALS patients were included; median [interquartile range] follow-up was 25.0 months [15.3–43.3]. During study timeframe patients had a median of 4.0 [2.0–6.0] clinical visits; death occurred in 54.1%. Median time between clinical visits was 3.9 [2.8–6.5] months, between arterial blood gases was 4.3 months [3.0–6.6], between spirometry testing was 5.8 months [4.1–8.2], and between nocturnal oximetry was 4.4 months [3.0–7.8]. Visualization of care trajectories TAK show marked heterogeneity in survival, time to NIV initiation, and time from NIV initiation to death. Mortality was correlated with NIV initiation and arterial carbon dioxide pressure increase. Conclusions: The current framework in ALS guidelines should be adapted to the ALS disease stage and individual patient characteristics. Understanding how subgroups of patients with ALS use healthcare services over time could help to highlight fragility areas and priorities in the allocation of care resources and implementation of best practices.
‘Frederick Street’ - Feasibility Study Immersive Digital Story
Creators: name: Turpin, Holly
Publisher: name: Loughborough University
Year: 2025

description: A 360 degree narrated video.

A co-created immersive digital story from a feasibility study part of the PhD research 'Understanding Homelessness in Loughborough Through Co-Creative Immersive Digital Storytelling'.
‘Frederick Street’ - Feasibility Study Immersive Digital Story
Creators: name: Turpin, Holly
Publisher: name: Loughborough University
Year: 2024

description: A 360 degree narrated video.

A co-created immersive digital story from a feasibility study part of the PhD research 'Understanding Homelessness in Loughborough Through Co-Creative Immersive Digital Storytelling'.
ZeroPM science-policy webinar 7 - Update on the PFAS restriction proposal
Creators: name: Dannenburg, Carl
Publisher: name: Zenodo
Year: 2025

description: The slides that were presneted at the 7th ZeroPM science - policy workshop held on the 8th of May 2025. The presentation was given by Carl Dannenburg from BaUA and had the title "Update on the PFAS restriction proposal".

Please note the slides represent the status at the time of the presentation - 8th May 2025, and future changes to any aspect of the universal PFAS restriction is beyond the control of the authour.
Anti-Trypanosoma cruzi activity of clerodane diterpenes and their methyl ester derivatives from Aquarius grandiflorus (Alismataceae)
Creators: name: Borges, Mariana Magalhães
name: Moriconi, João Pedro Valdo
name: de Pinho, Amanda Oliveira
name: Londero, Vinicius Silva
name: Tempone, Andre G.
name: Lago, João Henrique G.
name: Ferreira, Edgard Antonio
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Chemical Sciences not elsewhere classified

description: The effect of the EtOAc extract of Aquarius grandiflorus leaves against Trypanosoma cruzi (trypomastigotes) was evaluated in vitro. As this extract caused 100% parasite reduction (at 300 µg/mL), it was subjected to chromatographic fractionation to obtain two related diterpenes, clerodermic (1) and patagonic (2) acids. Both compounds showed antiparasitic potential against T. cruzi with EC50 of 41.7 µM (trypo)/60.7 µM (ama) and 37.6 µM (trypo)/73.1 µM (ama), respectively. Considering that the antiparasitic activity of carboxylic acid diterpenoids may be enhanced after esterification, methylation of both compounds was performed. The EC50 values for methyl esters 1a and 2a were determined to be 19.7 µM (trypo)/7.5 µM (ama) and 21.8 µM (trypo)/9.3 µM (ama), respectively. Based on the potency of the methyl esters, they may be future candidates for optimisation studies to design new drugs for treatment of Chagas’ disease.
title: Primary mediastinal choriocarcinoma with lung metastases
Creators: name: Vanrietvelde, Bastiaan
Publisher: name: EURORAD
Year: 2025
Subjects: subject: Chest imaging
subject: Mediastinum
subject: Thorax
subject: CT
subject: Clinical Case

description: Clinical History: A 32-year-old man with erectile dysfunction and bilateral gynaecomastia showed elevated prolactin (21.3 µg/L), testosterone (1348 ng/dL total testosterone) and human chorionic gonadotropin (38.3 U/L) levels. Further work-up showed normal breast ultrasound and scrotum ultrasound.

description: 32 years, male
Computer-aided mathematical and structural optimization using an advanced stochastic algorithm
Creators: name: Goodarzimehr, Vahid
name: Fanaie, Nader
name: Mirjalili, Seyedali
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: In this study, the Special Relativity Search convergence rate is boosted based on the Gradient Descent mechanism for the optimum design of numerical and engineering problems. The mathematical model presented for Special Relativity Search is based on the interaction of particles in a magnetic field that moves under the effect of the Lorentz force. Because the particles in the magnetic field are lightweight and are moving at a high speed, Newtonian physics cannot be used to provide a mathematical model. Therefore, the physics of special relativity is used to develop the equations. Gradient Descent starts processing with a random point in the feasible space and moves in the negative direction from the gradient of the objective function toward the optimal point. Standard Special Relativity Search suffers from a weak local search and cannot search all the possible local optima, which leads to premature convergence. Applying Gradient Descent in the Special Relativity Search’s velocity vector, it is possible to find the local optima with higher accuracy and move the swarm toward the optimal point. Then, in the next step, Special Relativity Search, which has a high exploratory capability, moves toward the global optimum. A total of 160 bound constraints CEC-2021 and seven engineering problems with continuous, discrete, and combinatorial variables are presented. Friedman’s statistical test is utilized to rank and select the best algorithm. The results show that Special Relativity Search based Gradient Descent provides better outcomes compared to other metaheuristic methods in the majority of case studies.
sj-pdf-1-jcb-10.1177_0271678X20961854 - Supplemental material for Large-scale characterization of the microvascular geometry in development and disease by tissue clearing and quantitative ultramicroscopy
Creators: name: Hahn, Artur
name: Bode, Julia
name: Alexander, Allen
name: Kianush Karimian-Jazi
name: Schregel, Katharina
name: Schwarz, Daniel
name: Sommerkamp, Alexander C
name: Krüwel, Thomas
name: Abdollahi, Amir
name: Wick, Wolfgang
name: Platten, Michael
name: Bendszus, Martin
name: Tews, Björn
name: Kurz, Felix T
name: Breckwoldt, Michael O
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 110306 Endocrinology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 110320 Radiology and Organ Imaging
subject: Cell Biology
subject: Biochemistry
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jcb-10.1177_0271678X20961854 for Large-scale characterization of the microvascular geometry in development and disease by tissue clearing and quantitative ultramicroscopy by Artur Hahn, Julia Bode, Allen Alexander, Kianush Karimian-Jazi, Katharina Schregel, Daniel Schwarz, Alexander C Sommerkamp, Thomas Krüwel, Amir Abdollahi, Wolfgang Wick, Michael Platten, Martin Bendszus, Björn Tews, Felix T Kurz and Michael O Breckwoldt in Journal of Cerebral Blood Flow & Metabolism
sj-pdf-1-mso-10.1177_2055217320964502 - Supplemental material for Enlarged perivascular spaces are not associated with vascular co-morbidities, clinical outcomes, and brain volumes in people with secondary progressive multiple sclerosis
Creators: name: Wooliscroft, Lindsey
name: Boespflug, Erin
name: Hildebrand, Andrea
name: Shangraw, Kathleen
name: Silbermann, Elizabeth
name: Bourdette, Dennis
name: Spain, Rebecca
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Neuroscience

description: Supplemental material, sj-pdf-1-mso-10.1177_2055217320964502 for Enlarged perivascular spaces are not associated with vascular co-morbidities, clinical outcomes, and brain volumes in people with secondary progressive multiple sclerosis by Lindsey Wooliscroft Dennis Bourdette and Rebecca Spain in Multiple Sclerosis Journal – Experimental, Translational and Clinical
Impact of access point density on driving safety in underground loops: Examining drivers’ operational performance and visual characteristics
Creators: name: Zhang, Ting
name: Chen, Feng
name: Song, Mingtao
name: Chen, Zheng
name: Shi, Hailin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Neuroscience
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Underground loops, which are characterized by multiple access points (APs) and an enclosed environment, present unique driving safety challenges. This study investigated the impact of AP densities on driving safety in underground loops. We conducted field tests utilizing four AP conditions (7, 9, 12, and 14 APs/km) and collected data on drivers’ operational performance and visual characteristics. To analyze the differences in driving behavior across these conditions, one-way repeated measures ANOVA was applied. Additionally, a comprehensive evaluation model based on matter-element extension analysis was developed to evaluate the impact of AP density on driving safety. The results indicated that AP density significantly affects acceleration variations and eye movement characteristics. As the density of APs increased, drivers demonstrated improved speed control and enhanced driving stability. However, this also resulted in a wider visual search range, increased visual recognition difficulty, and a higher mental workload. The comprehensive evaluation revealed that under 7 APs/km conditions, the overall evaluation grade was “Good,” indicating better driving safety. In contrast, the 14 APs/km condition received a grade of “Poor,” suggesting a higher driving risk. These findings provide guidance for transportation management agencies aiming to improve driving safety in underground loops.
Supplemental Material, 005FV_13.7.20_Title_page_Manuscrit_overweighte_and_dietary_habits_and_physical_activity.docx - Weight status, dietary habits, physical activity, screen time and sleep duration among university students
Creators: name: Benaich, Souad
name: Mehdad, Slimane
name: Zineb Andaloussi
name: Boutayeb, Saber
name: Alamy, Meryem
name: Aguenaou, Hassan
name: Taghzouti, Khalid
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, 005FV_13.7.20_Title_page_Manuscrit_overweighte_and_dietary_habits_and_physical_activity.docx for Weight status, dietary habits, physical activity, screen time and sleep duration among university students by Souad Benaich, Slimane Mehdad, Zineb Andaloussi, Saber Boutayeb, Meryem Alamy, Hassan Aguenaou and Khalid Taghzouti in Nutrition and Health