cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Proteomics instrumentation development in densitometry, electrophoresis, and microplates
Creators: name: Tan, Han Yen
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Proteomic studies are highly dependent on instrumentation. In this project, aspects of electrophoresis, densitometry and microplate technology have been developed. In the work on densitometry, the first notion was to develop a refined laser densitometer system. In view of the prohibitive cost of such a system, adapted flatbed scanners were developed instead to quantify electrophoresis gels with the aid of accurate optical density calibration using step wedges. Various aspects of illumination using light emitting diode and liquid crystal display backlighting were also investigated. In advancing the microplate technology, the use of microplate wells to function like capillaries for filling of samples in high throughput screening without precise instrumentation was introduced. The principle of light shielding and total internal reflection by light emitting diodes was also implemented for non imaging quantification of protein samples without optical filters. With the imaging quantification approach, the problematic effects of point spread function and liquid meniscus of small liquid volumes on standard microplates were shown. In that vein, the capability of our capillary wells microplate design to overcome this limitation was demonstrated. In another aspect of imaging quantification, an innovative capillary wells microplate approach that permitted side viewing, as compared to standard microplates which only allows top viewing, was implemented. With this approach, errors arising from bubbles during measurement could be revealed and pipetting errors detected during actual assay runs. In the effort related to electrophoresis, we developed a coverslip fluidic approach that potentially could be used for simple and cost effective capillary electrophoresis. Currently, this is done using capillary tubes which makes quantification possible only with specialized instrumentation.
3D for D3 right colon resection: role of anatomy
Creators: name: Stimec, Bojan
Publisher: name: Université de Genève
Year: 2018
Subjects: info:eu-repo/classification/ddc/612
D3 right colectomy
Anatomy
Vascular roadmapping
Lymphatic resection

description: The D3 right colectomy with extended lymphadenectomy has proven higher oncological quality. The prerequisites for such performing this radical operation are good anatomical knowledge of the lymph node and vessel distribution in the D3 area and a precise morphometric insight in the individual patient's three-dimensional vascular pattern of the superior mesenteric vessels, their branches and affluents. This is accomplished by engaging a professional anatomist in the multi-centric randomized, prospective clinical trial “Safe radical D3 right hemicolectomy for cancer through preoperative biphasic MDCT angiography”. A 3D vascular road mapping based on segmentation of high-resolution pre-operative CT can accurately present the multitude of vascular variations and anomalies, rendering the D3 surgical procedure safe and efficient. An anatomical micro-dissectional study has given valuable data concerning the actual morphometry and the 3D pattern of the colic artery lymphovascular bundle, i.e. defining the limits and extent of a sufficient lymphatic resection during D3 colectomy.
Private Sequential Hypothesis Testing for Statisticians: Privacy, Error Rates, and Sample Size
Creators: name: Zhang, Wanrong
name: Mei, Yajun
name: Cummings, Rachel
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: Statistics Theory (math.ST)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: The sequential hypothesis testing problem is a class of statistical analyses where the sample size is not fixed in advance. Instead, the decision-process takes in new observations sequentially to make real-time decisions for testing an alternative hypothesis against a null hypothesis until some stopping criterion is satisfied. In many common applications of sequential hypothesis testing, the data can be highly sensitive and may require privacy protection; for example, sequential hypothesis testing is used in clinical trials, where doctors sequentially collect data from patients and must determine when to stop recruiting patients and whether the treatment is effective. The field of differential privacy has been developed to offer data analysis tools with strong privacy guarantees, and has been commonly applied to machine learning and statistical tasks. In this work, we study the sequential hypothesis testing problem under a slight variant of differential privacy, known as Renyi differential privacy. We present a new private algorithm based on Wald's Sequential Probability Ratio Test (SPRT) that also gives strong theoretical privacy guarantees. We provide theoretical analysis on statistical performance measured by Type I and Type II error as well as the expected sample size. We also empirically validate our theoretical results on several synthetic databases, showing that our algorithms also perform well in practice. Unlike previous work in private hypothesis testing that focused only on the classical fixed sample setting, our results in the sequential setting allow a conclusion to be reached much earlier, and thus saving the cost of collecting additional samples.
Additional file 1: of Utility of posaconazole therapeutic drug monitoring and assessment of plasma concentration threshold for effective prophylaxis of invasive fungal infections: a meta-analysis with trial sequential analysis
Creators: name: Chen, Lu
name: Wang, Yan
name: Zhang, Tao
name: Li, Ying
name: Meng, Ti
name: Liu, Leichao
name: Hao, Ruifang
name: Dong, Yalin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S1. Summary of sensitive analysis for prophylaxis efficacy. Figure S1. Source of bias in two randomized trials following Cochrane Collaborationâ s tool. Figure S2. Sensitive analysis of individual study involved at cut-off value of 0.5Â mg/L (A) and 0.7Â mg/L (B). Statement for detailed searching strategy. (PDF 301 kb)
Four days of light and it’s dark again: dementia care in India
Creators: name: Brijnath, Bianca
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: As the world ages, the prevalence of age-related diseases like dementia will increase. In South Asia and the Western Pacific regions, particularly India and China, rates of dementia are expected to escalate by 314-336 percent in four decades (Ferri et al., 2005b). Yet there is limited work on dementia in this region – on idioms of dementia and ageing, understandings of rights and entitlements, and experiences of caregiving. In redressing this gap, this thesis adds to the current literature by examining the lives of urban Indian families who care for a person living with dementia. The main research question is: In New Delhi, India, how are people with age-related dementia cared for and what are the barriers to carers to access support? Data were gathered in Delhi, with additional work in Kolkata, Bangalore and parts of Kerala. A critical ethnographic method was used. From January to October 2008, in Delhi, 20 families caring for a person with dementia were followed to document their understanding and experiences of diagnosis and prognosis, medication management, enablers and barriers to care, and the extent to which this varied by class, gender, caste and age. This was supplemented with 21 interviews with key service providers and approximately 250 hours of observation in home, hospital and community settings. I argue that caregiving is intimate work and deeply felt but that carers also draw upon broader frameworks – medical pluralism and hope for a cure, the emotional currency of feeding and eating, and the powerful bonds of kinship and reciprocity – to make sense of their everyday worlds and practices. I describe how carers and people with dementia engage with institutions of health, law and money, which exclude and exploit them at different points but that these practices in turn are shaped by shortages in resources and capacity. Existing systems, inequities and roles are challenged as illness and loss forces changes in identity for the carer and the person with dementia. Ultimately what I will show is that care work is ambiguous; at once full of cruelty, tragedy and exploitation but also hope, kinship, and love. It is only through explicating these aspects of care, can we begin to think of culturally meaningful ways to support families and people with dementia.
Additional file 1: of SGK1 inhibition-induced autophagy impairs prostate cancer metastasis by reversing EMT
Creators: name: Liu, Weiwei
name: Wang, Xuchu
name: Wang, Yiyun
name: Dai, Yibei
name: Xie, Yiyi
name: Ping, Ying
name: Yin, Binbin
name: Yu, Pan
name: Liu, Zhenping
name: Duan, Xiuzhi
name: Liao, Zhaoping
name: Chen, Yuhua
name: Liu, Chunhua
name: Li, Xiang
name: Tao, Zhihua
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Figure S1. GSK650394 impairs DU145 cells migration capability.Wound healing assays of DU145 cells treated with DMSO or 20 μM GSK650394. Phase-contrast images were acquired at 0 and 24 h after scratching and representative images of three independent experiments are shown. The wound healing area was analyzed by using ImageJ software and the corresponding data, relative to 0 h, expressed in the graph. (DOCX 961 kb)
Additional file 3: of New indexes of body fat distribution and sex-specific risk of total and cause-specific mortality: a prospective cohort study
Creators: name: Rost, Susanne
name: Freuer, Dennis
name: Peters, Annette
name: Thorand, Barbara
name: Holle, Rolf
name: Linseisen, Jakob
name: Meisinger, Christa
Publisher: name: figshare
Year: 2018
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology

description: Different anthropometric measures and CVD mortality. Hazard ratios (HR) and confidence intervals (CI) for the association between the different anthropometric measures and CVD mortality for persons <=/>â 60Â years by quartiles; the second quartile was set as the reference category. (DOCX 21Â kb)
Additional file 4: of New indexes of body fat distribution and sex-specific risk of total and cause-specific mortality: a prospective cohort study
Creators: name: Rost, Susanne
name: Freuer, Dennis
name: Peters, Annette
name: Thorand, Barbara
name: Holle, Rolf
name: Linseisen, Jakob
name: Meisinger, Christa
Publisher: name: figshare
Year: 2018
Subjects: subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Different anthropometric measures and cancer mortality. Hazard ratios (HR) and confidence intervals (CI) for the association between the different anthropometric measures and cancer mortality for persons <=/>â 60Â years by quartiles; the second quartile was set as the reference category. (DOCX 21Â kb)
Additional file 1: of RNA-seq analysis of lncRNA-controlled developmental gene expression during puberty in goat & rat
Creators: name: Gao, Xiaoxiao
name: Ye, Jing
name: Yang, Chen
name: Luo, Lei
name: Liu, Ya
name: Ding, Jianping
name: Zhang, Yunhai
name: Ling, Yinghui
name: Huang, Weiping
name: Zhang, Xiaorong
name: Zhang, Kaifa
name: Li, Xiumei
name: Zhou, Jie
name: Fang, Fugui
name: Cao, Zubing
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: The identification of the first estrous cycle phase. (DOCX 4296 kb)
Transmission policy for wireless sensor networks
Creators: name: Azad, AKM
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Wireless sensor networks (WSNs) are commonly recognized as the technological cornerstone in achieving ubiquitous computing, where future computing devices will be invisibly embedded in the world around us and accessed through simple and intelligent interfaces. From applications’ perspective, WSNs can be classified as data gathering and query-based networks, where in the former, sensors send their data proactively, either periodically or on detecting some events, and in the later, sensors only report in response to explicit user request. Irrespective of their data models, deployment of a WSN posses a number of technical challenges that stem primarily from i) the constraints imposed by simple sensor devices, e.g., limited power, transmission range, bandwidth, etc., ii) the node heterogeneity in terms of data rate, energy storage, deployment density, etc., and iii) the scalability since the network size and the number of nodes deployed can vary widely. Moreover, WSNs exhibit highly unbalanced traffic flow due to the many-to-one communication paradigm, where a large number of sensors communicate concomitantly with a central sink which reduces network lifetime drastically. This thesis aims to address these issues by developing transmission policy for transmitting sensor data which regulates the communication ranges and their associated duty cycles that nodes use over lifetime. The policy attains efficient and balanced energy usage among sensors despite the inherent unbalanced traffic flow of WSNs and thereby, significantly extends the network lifetime, a key deployment issue. We start by designing transmission policies for data gathering homogeneous sensor networks, where the transmission policies differ in terms of their degree of flexibility in using variable transmission ranges and associated duty cycles among nodes. Then, we extend our formulations for multi-tier heterogeneous sensor networks. We develop a traffic model considering collaboration among multiple services deploying multiple classes of heterogeneous sensors. Finally, we propose a distributed query optimization and processing framework for such collaborative heterogeneous sensor networks. Vigorous analytical and experimental analyses confirm the efficacy of the proposed new strategies over the notable works in the related area.
The market reaction to stock splits and the ability to earn abnormal returns
Creators: name: Nguyen, Phuong Anh
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: A stock split is often regarded as a pure cosmetic accounting treatment and yet prior research shows that the market reacts positively upon the arrival of the split announcement. However, up to now, there has not been any convincing explanation for this favourable response while there is intense debate amongst researchers about whether these positive abnormal returns persist in the future. We revisit the issues related to the performance of splitting companies both around and following the announcement date. This allows us to study the information content of the event and assess whether the market has incorporated the implication of such information in a timely manner. In addition, we hope to draw meaningful inference about the profitability of trading following the announcement date. Our findings suggest that there is information in the split announcements, which is positively valued by the market. However, abnormal returns cannot be earned with certainty following the event. This is evident in both the option market and the stock market. Specifically, if informed investors use the option market to trade on their information, then our results indicate that informed investors do not believe in the success of a strategy that buys splitting companies subsequent to the announcement date. This is because the post-split announcement drift does not exist following every split; it is conditioned on whether the firms will split again in the future. While prior studies argue that the long-run abnormal returns are sensitive to the time period, we find that the aggregate long-run abnormal returns are higher in a time period where there is a large proportion of companies that split multiple times. Nevertheless, knowing whether the companies have split multiple times in the past will not lead to positive abnormal returns ex-ante; these returns can only be guaranteed if investors are able to forecast accurately which sample firms will implement another split in the future. Once the split again condition is controlled for, there is no role for the time period to influence the magnitude and significance of the abnormal returns. We also discover that firms that have not split before consistently outperform firms that have. This implies that instead of buying every company that splits, investors can achieve higher returns by focusing on those that have not split in the recent past. However, the profitability of this strategy depends on the state of the market (bull versus bear market). In summary, the thesis shows that while stock splits are perceived as good news by investors, abnormal returns cannot be guaranteed following the announcement date. The information contained in a stock split is incorporated into stock prices in a timely manner, however, what type of information this event is capturing remains an open question.
The schematic diagram for oxytocin in ischemia/reperfusion injury
Creators: name: Xiong, Wei
Publisher: name: Zenodo
Year: 2020

description: Supplemental figure 1. Schematic diagram. (A) Preliminary experiment: Thirty-six rats were assigned to sham, MIRI, EOT-I/R, LOT-I/R, MOT-I/R, and HOT-I/R stochastically. EOT-I/R with forced swimming for 30 min. LOT-I/R, MOT-I/R and HOT-I/R were pretreated with 0.01 μg/kg, 0.1 μg/kg or 1 μg/kg OT respectively. (B) Formal experiment: Seventy-two rats were randomized into CK, I/R, OTP-I/R, MCD, MCD-I/R, and OTP-MCD-I/R. OTP-I/R and OTP-MCD-I/R were pretreated with OT (0.1 μg/kg, i.p) for 30 min before MIRI operation. MCD, MCD-I/R, and OTP-MCD-I/R were administrated with C48/80 (0.5 mg/kg, i.v.) before I/R injury. Except for the animals in sham, CK, and MCD groups, which were threaded without ligation, the animals in other groups underwent I/R injury, which were mediated by ligature for 30 min and reperfusion for 120 min. (C) Cell experiment: H9C2(2-1) and RBL-2H3 cells were cocultured and then randomly divided into the following 3 groups: Group S, untreated; Group C, treated with C48/80 (10 μg/ml) for 30 min; Group OC, OT (0.01 ng/ml) pretreated for 60 min, followed by C48/80 (10 μg/ml) treated for 30 min. Black arrows indicate the time points of different interventions or monitoring indicators. FST, forced swimming test; UM, untreated medium; i.p., intraperitoneal injection; i.v., intravenous injection.
Supporting Data: The ‘strength of weak ties’ among female baboons: fitness-related benefits of social bonds.
Creators: name: Mcfarland, Richard
name: Murphy, Derek
name: Lusseau, David
name: Henzi, Peter
name: Parker, Jessica
name: Pollet, Thomas
name: Barrett, Louise
Publisher: name: figshare
Year: 2017
Subjects: subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Supporting data: The ‘strength of weak ties’ among female baboons: fitness-related benefits of social bonds. Animal Behaviour.
Causal models for a risk-based assessment of stressor pathways for an operational uranium mine
Creators: name: Bartolo, Renée E.
name: Harford, Andrew J.
name: Bollhöfer, Andreas
name: Dam, Rick A. Van
name: Parker, Scott
name: Breed, Krissy
name: Erskine, Wayne
name: Humphrey, Chris L.
name: Jones, David
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Protection of the environment and people from the potential impacts of uranium mining and milling is a global issue as the world's demand for power generation derived from uranium increases. We present a framework for deriving multiple stressor-pathway causal models for an operational uranium mine that can be used to identify research and monitoring needs for environmental protection. Additionally the framework enabled us to categorize the importance of pathways in the system. An interdisciplinary approach to causal model development was undertaken in order to ensure the potential impacts of mining on the natural environment and human health were identified and assessed by researchers with the appropriate knowledge. An example of a causal model and supporting narrative is provided for the most important stressor pathway, transport of inorganic toxicants via the surface water to surface water pathway. This risk-based screening approach can be applied to mining operations where environmental protection (including human health) is underpinned by quantitative interdisciplinary research and monitoring.
Immunological issues of blood transfusion
Creators: name: Waldvogel Abramowski, Sophie
Publisher: name: Université de Genève
Year: 2019
Subjects: info:eu-repo/classification/ddc/616
Blood transfusion
Alloimmunization

description: Cette thèse traite des différents mécanismes immunologiques qui s'opposent aux transfusions sanguines homologue.
A facile method for regioselective synthesis of new N-acetyl/thioacetyl-(E)-stilbene benzenesulfonamide derivatives via N-acetyl/thioacetyl sulfonamide formation
Creators: name: Ahmadian-Moghaddam, Maryam
name: Ahmadreza Bekhradnia
name: Monire Tatar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A series of new N-acetyl/thioacetyl-(E)-stilbene benzenesulfonamide derivatives were synthesized regioselectively in moderate to high yields by following a convenient, three-step procedure. The procedure consists of the direct oxidative conversion of a thiol compound to the corresponding sulfonyl chloride using TMSCl/KNO3, followed by a room temperature reaction in a one-pot transformation of the resultant sulfonyl chloride into N-acetyl/thioacetyl sulfonamide, which undergoes a further Pd-catalyzed coupling reaction, giving rise to the stilbene compounds reported for the first time.
Additional file 2: of A high-resolution genetic linkage map and QTL fine mapping for growth-related traits and sex in the Yangtze River common carp (Cyprinus carpio haematopterus)
Creators: name: Feng, Xiu
name: Yu, Xiaomu
name: Fu, Beide
name: Wang, Xinhua
name: Liu, Haiyang
name: Pang, Meixia
name: Tong, Jingou
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: Figure S1. Genomic synteny visualized using Oxford grids between linkage groups of C. c. haematopterus and LGs of C. c. carpio. (PDF 1100Â kb)
Additional file 3: of A high-resolution genetic linkage map and QTL fine mapping for growth-related traits and sex in the Yangtze River common carp (Cyprinus carpio haematopterus)
Creators: name: Feng, Xiu
name: Yu, Xiaomu
name: Fu, Beide
name: Wang, Xinhua
name: Liu, Haiyang
name: Pang, Meixia
name: Tong, Jingou
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Figure S2. Genomic synteny visualized using Oxford grids between linkage groups of C. c. haematopterus and chromosomes Danio rerio. (PDF 32Â kb)
Neutron spectroscopy evidence for a possible magnetic-field-induced gapless quantum-spin-liquid phase in a Kitaev material $α$-RuCl$_3$
Creators: name: Zhao, Xiaoxue
name: Ran, Kejing
name: Wang, Jinghui
name: Bao, Song
name: Shangguan, Yanyan
name: Huang, Zhentao
name: Liao, Junbo
name: Zhang, Bo
name: Cheng, Shufan
name: Xu, Hao
name: Wang, Wei
name: Dong, Zhao-Yang
name: Meng, Siqin
name: Lu, Zhilun
name: Yano, Shin-ichiro
name: Yu, Shun-Li
name: Li, Jian-Xin
name: Wen, Jinsheng
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: As one of the most promising Kitaev quantum-spin-liquid (QSL) candidates, $α$-RuCl$_3$ has received a great amount of attention. However, its ground state exhibits a long-range zigzag magnetic order, which defies the QSL phase. Nevertheless, the magnetic order is fragile and can be completely suppressed by applying an external magnetic field. Here, we explore the evolution of magnetic excitations of $α$-RuCl$_3$ under an in-plane magnetic field, by carrying out inelastic neutron scattering measurements on high-quality single crystals. Under zero field, there exist spin-wave excitations near the $M$ point and a continuum near the $\mitΓ$ point, which are believed to be associated with the zigzag magnetic order and fractional excitations of the Kitaev QSL state, respectively. By increasing the magnetic field, the spin-wave excitations gradually give way to the continuous excitations. On the verge of the critical field $μ_0H_{\rm c}=7.5$ T, the former vanish and only the latter is left, indicating the emergence of a pure QSL state. By further increasing the field strength, the excitations near the $\mitΓ$ point become more intense. By following the gap evolution of the excitations near the $\mitΓ$ point, we are able to establish a phase diagram composed of three interesting phases, including a gapped zigzag order phase at low fields, possibly-gapless QSL phase near $μ_0H_{\rm c}$, and gapped partially polarized phase at high fields. These results demonstrate that an in-plane magnetic field can drive $α$-RuCl$_3$ into a long-sought QSL state near the critical field.
description: 9 pages, 4 figures
Additional file 4: of A high-resolution genetic linkage map and QTL fine mapping for growth-related traits and sex in the Yangtze River common carp (Cyprinus carpio haematopterus)
Creators: name: Feng, Xiu
name: Yu, Xiaomu
name: Fu, Beide
name: Wang, Xinhua
name: Liu, Haiyang
name: Pang, Meixia
name: Tong, Jingou
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: Figure S3. Genomic synteny visualized using Oxford grids between linkage groups of C. c. haematopterus and LGs of Ctenopharyngodon idellus. (PDF 31Â kb)
Non-alcoholic fatty liver disease: molecular mechanisms induced by free fatty acids
Creators: name: Foti, Michelangelo
Publisher: name: Université de Genève
Year: 2010
Subjects: info:eu-repo/classification/ddc/612
Non-alcoholic fatty liver diseases
Steatosis
Insulin resistance
Steatohepatitis
Fibrosis
Hepatocellular carcinoma
Fatty acids
PTEN

description: [No abstract]
Вестник Харьковского Регионального Института Проблем Общественного Здравоохранения, 2019, 6(92)
Creators: name: Шевченко А.С., ред.
Publisher: name: Zenodo
Year: 2019
Subjects: периодическое научное издание

description: RU: Вестник Харьковского Регионального Института Проблем Общественного Здравоохранения / ред. Шевченко А.С. - 2019. - Том 92, № 6. - 87 с. https://doi.org/10.5281/zenodo.3694367 UA:  Вісник Харківського Регіонального Інституту Проблем Громадської Охорони Здоров'я / ред. Шевченко О.С. - 2019. - Том 92, № 6. - 87 с. https://doi.org/10.5281/zenodo.3694367 EN:  Bulletin of Kharkov Regional Institute of Public Health Services / ed. Shevchenko A.S. - 2019. - Vol. 92, No. 6. - 87 p. https://doi.org/10.5281/zenodo.3694367 На странице института https://www.facebook.com/permalink.php?story_fbid=2546435988977701&id=2352104365077532
title: Comparative analysis of vertical green façades with movable panels from the perspective of their thermal performance  and applicability in sustainable urban areas
Creators: name: Seyrek Şık, Cansu Iraz
name: Widera, Barbara
Publisher: name: Conference Proceedings XXIX International Seminar on Urban Form ISUF 2022 Urban Redevelopment and Revitalisation A Multidisciplinary Perspective/Lodz University of Technology Press
Year: 2023
Subjects: Vertical green façades, Movable green panels, Energy efficient cities, New European Bauhaus

description: The positive effects of urban green spaces on both the health of city residents and urban ecosystems cannot be denied. Green urban spaces help prevent environmental problems such as air pollution, urban heat island effect and are necessary for citizens to socialize, appreciate nature and foster a healthier society. However, with the urban tissue densification, decrease is observed in the amount of green urban areas. During the revitalization process, in order to create inclusive and sustainable cities, it is important to design alternative green public spaces. We argue that vertical green façade systems can be used as one of the most effective options for active interaction between the residents and nature. The perspective for the vertical green spaces as an important part of the holistic approach to the decarbonization and urban green transition is discussed in the light of the New European Bauhaus.
The purpose of this study is to present a comparative review of vertical green façades with the perspective of their thermal performance. The authors highlight the energy saving potential of vertical green systems for different spatial, structural and bioclimatic solutions. Moreover, as a result of this review, the authors explain the parameters that designers should consider for achieving the best thermal performance of a vertical green system. The paper also analyses the pros and cons of the application of movable green panels.
Le temps dans les traductions français-mandarin et mandarin-français : convergence ou divergence ?
Creators: name: Sun, Juan
name: Grisot, Cristina
Publisher: name: Université de Genève
Year: 2019
Subjects: info:eu-repo/classification/ddc/410
Temps verbaux du français
Corpus de traduction
Langue tensée
Langue non-tensée
Expression du temps en mandarin
Particules aspectuelles
Divergence formelle

description: Se plaçant dans la continuité des travaux théoriques, cet article présente une étude empirique basée sur corpus, dans le but de montrer comment le temps est exprimé et traduit d'une langue tensée (le français) vers une langue non-tensée du point de vue de la morphologie flexionnelle (le mandarin) et vice versa. En nous appuyant d'abord sur des descriptions théoriques, puis sur les résultats des analyses quantitatives des données, nous montrerons que la divergence perceptible au niveau formel est associée à une convergence identifiable au niveau de l'interprétation temporelle pertinente dans un contexte donné. La traduction d'une langue source vers une langue cible présente des ajustements systématiques au niveau formel pour que l'information temporelle pertinente puisse être identifiée avec succès dans la langue cible.
Appréhender le mécanisme du sens à travers la structure des concepts ad hoc
Creators: name: Gouroubera, Sayane
Publisher: name: Université de Genève
Year: 2019
Subjects: info:eu-repo/classification/ddc/410
Concepts "ad hoc"
Récursivité
Mécanisme
Sens
Pertinence

description: Les concepts "ad hoc" sont le résultat d'ajustements contextuels du sens des mots. Le calcul de la dénotation de ces concepts passe par la spécification de leur contenu encyclopédique et logique par inférence. Le présent travail vise à décrire la structure des concepts "ad hoc" dans une perspective atomiste et pertinentiste. Il s'agira pour nous de formaliser systématiquement le mécanisme de sélection des entrées logiques et encyclopédiques des concepts, au regard des principes de pertinence et d'en tirer des leçons.
The Research Software Engineer (RSE) - Who is that? A perspective from within the community
Creators: name: Goth, Florian
Publisher: name: Zenodo
Year: 2024

description: The Research Software Engineer (RSE) - Who is that? A perspective from within the community

At a community workshop at the RSE23 in Paderborn we talked about teaching RSEs. Among the questions considered were, what are the basic competencies of RSEs? Which institutions are required? Which changes are necessary in the current academic system? After this workshop we started to gather the input from the community and quickly noticed that the scope is bigger than a single short publication, and therefore the TeachingRSE project was born. In this talk I will present our first publication, on the foundational competencies of an RSE. In addition I will detail future steps of the projects and possibilities for contributing.
Additional file 6: of A high-resolution genetic linkage map and QTL fine mapping for growth-related traits and sex in the Yangtze River common carp (Cyprinus carpio haematopterus)
Creators: name: Feng, Xiu
name: Yu, Xiaomu
name: Fu, Beide
name: Wang, Xinhua
name: Liu, Haiyang
name: Pang, Meixia
name: Tong, Jingou
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences

description: Figure S4. The QTL region for head length on LG5 of C. c. haematopterus and its homologous region in genomes of Danio rerio and Ctenopharyngodon idellus. (PDF 135Â kb)
OUR STORIES, OUR EXPERIENCES AND THEIR IMPACT IN OUR CLASSROOM
Creators: name: Olive, Heriberto
Publisher: name: Zenodo
Year: 2022
Subjects: emergent multilingual
case study
comparative
asset-based
English learner
lifelong learner

description: The impact that labels such as English Learner (EL) have on students can have unintended lasting effects. In this qualitative comparative case study, six participants tell their stories growing up either an EL or not and the impact it has led to in their profession and practice. This was done through pre-survey questions, semi-structured interviews with participants, classroom observations, and a final reflection. This led to a within-case study analysis that looked at each participant individually and followed with a cross-case analysis that examined all participants against one another. The findings showed the negative impact that being labeled an EL had-on teachers by discussing their resentment and experiences as EL students. In comparison, teachers that were never labeled showed no negative impact. All participants shared the commonality of developing lifelong learners regardless of their label. Teachers used their experiences and perceptions of their own EL students to shape their practice in how they deliver their instruction and lesson to their students.
A green one-pot three-component synthesis of α-aminophosphonates under solvent-free conditions and ultrasonic irradiation using Fe3O4@SiO2-imid-PMAn as magnetic catalyst
Creators: name: Esmaeilpour, Mohsen
name: Zahmatkesh, Saeed
name: Javidi, Jaber
name: Elahe Rezaei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: An efficient and environment friendly process for the synthesis of α-aminophosphonates has been devised. Through a one-pot three-component condensation of various aldehydes, amines, and triethyl phosphite in the presence of Fe3O4@SiO2-imid-PMAn nanoparticles as magnetic catalysts under solvent-free conditions and ultrasonic irradiation, α-aminophosphonates were obtained with excellent yields. The reactions under solvent-free conditions at room temperature are compared with the ultrasonic-assisted reactions. This new procedure has notable advantages such as short reaction time, excellent yields, easy purification, and the absence of any tedious workup or purification. The aforementioned catalyst could be easily recovered by an external magnetic field and can be reused for six consecutive reaction cycles without significant loss of activity. In addition, SEM and DLS of the catalyst after the reaction cycle were investigated.
Le langage est-il vraiment un système de communication ambigu ?
Creators: name: Kabbach, Alexandre
Publisher: name: Université de Genève
Year: 2019
Subjects: info:eu-repo/classification/ddc/410
Langage et communication
Ambiguïté
Optimisation des systèmes de communication
Intelligence artificielle

description: Nous proposons de discuter de la question de l'ambiguïté du langage du point de vue du modèle de la communication de Shannon et Weaver (1949). Nous soutenons que le langage n'est pas un "système" de communication ambigu car (1) tout signal linguistique, même ambigu, peut être décodé par un récepteur une fois contextualisé ; et (2) seuls les signaux linguistiques contextualisés forment un objet d'étude pertinent pour statuer sur la nature ambiguë du langage en tant que système de communication, car eux seuls caractérisent les signaux échangés en situation réelle de communication. Nous soutenons que le problème du langage est davantage qu'il n'est pas un système de communication "efficace", en ce qu'il ne permet pas de s'assurer, au moment du décodage, que le message décodé par le récepteur est parfaitement identique au message encodé par l'émetteur. Nous proposons d'analyser cette inefficacité du langage à la lumière des différences structurelles existant entre les domaines contextuels utilisés par émetteurs et récepteurs pour encoder et décoder les messages transmis. Nous démontrons qu'en dépit de ces différences, les agents possèdent une compétence particulière à "faire sens" des signaux linguistiques auxquels ils sont exposés, c'est-à-dire à enrichir chaque signal linguistique d'un contexte non-linguistique permettant son décodage. Nous proposons de formaliser cette compétence comme fonction de réponse à un stimulus linguistique d'une intelligence artificielle. Nous démontrons qu'une telle formalisation permet de caractériser l'intelligence comme un processus de composition de concepts, où chaque concept peut être modélisé comme une combinaison linéaire d'un nombre fixe de concepts dits "primitifs". Nous concluons sur les connexions théoriques possibles entre notre formalisation et les travaux sur l'évolution du langage vue comme un mécanisme d'externalisation de la pensée (Reboul, 2017).
Fluxes - The European Greenhouse Gas Bulletin Volume 2: Nature-based solutions for net zero
Creators: name: ICOS ERIC
Publisher: name: ICOS ERIC
Year: 2023
Subjects: Greenhouse Gases
Carbon Cycle
Emission verification
Climate change

description: ICOS, the Integrated Carbon Observation System, is a European-wide greenhouse gas research infrastructure:
ICOS produces standardised data on greenhouse gas concentrations in the atmosphere, as well as on carbon fluxes between the atmosphere, the ecosystems, and the oceans. This ICOS-based knowledge supports policy and decision-making to combat climate
change and its impacts.
The high-quality ICOS data is based on the measurements from over 170 observation stations – run by top universities and research institutions across 16 European countries – and produced by the roughly 800 scientists in the community.
The ICOS Carbon Portal offers unlimited access to thousands of datasets and other advanced digital products and services. ICOS has the status of an ERIC, European Research Infrastructure Consortium, with a legal capacity recognised in all countries within the European Union.
FLUXES is a yearly publication by ICOS which aims at highlighting climate issues to an audience of policymakers, policy advisors, and climate journalists. The first volume was published in 2022.
In this issue the following topics are highlighted:
- Nature-based carbon sinks have a dual role in climate action
- The annual variability of carbon emissions and sinks
- The forest carbon sinks under pressure
- Coastal ecosystems, reservoirs of life
- Carbon farming - a path to more sustainable agriculture
- The complex chemistry behind the alarming growth in methane
Bien que : concession et corrélation
Creators: name: Lohiniva, Karoliina
Publisher: name: Université de Genève
Year: 2019
Subjects: info:eu-repo/classification/ddc/410
Connecteurs
Concession
Causalité
Corrélation
Common ground
At-issue

description: Dans cette contribution, nous verrons comment se passer de l'idée selon laquelle la concession doit être analysée en termes de causalité, sans pour autant perdre le lien intime et intuitif entre les deux notions. En particulier, il sera proposé que ce soit la corrélation, et non la causalité, qui intervient dans la présupposition concessive. Cette idée sera implémentée dans un modèle de discours dynamique où les locuteurs peuvent ajouter de l'information au common ground de leur conversation indirectement, en faisant des propositions d'ajouts, ou directement, en imposant une mise à jour du common ground. Spécifiquement, il sera proposé qu'au sein d'une structure concessive, la subordonnée donne lieu à une mise à jour impositive, ce qui change la ‘toile du fond' contre laquelle la principale est interprétée, et contribue à produire l'effet contre-tendanciel qui est associée à une présupposition causale ailleurs dans la littérature sur la concession.
Indexicaux diégétiques
Creators: name: Blunier, David Lucas Simon
Publisher: name: Université de Genève
Year: 2019
Subjects: info:eu-repo/classification/ddc/410
Indexicaux
Style indirect libre
Diégèse
David Kaplan
Gérard Genette
Sémantique
Dépendance au contexte

description: Cet article examine ce que récemment Maier (2017) a appelé « le puzzle du discours indirect libre », à savoir le fait que, dans ce genre particulier de discours, les pronoms et les temps, mais uniquement ceux-ci, semblent être pris en charge par le narrateur, tandis que le reste de l'énoncé rapporté, tant au niveau de son   contenu que de sa forme, semble être attribué entièrement au protagoniste. Mon analyse utilise les notions de contexte (au sens de Kaplan 1989), ainsi que de celle de diégèse telle qu'elle est définie par Gérard Genette (Genette 1966, 1972). Je soutiens que dans le discours indirect libre, les pronoms indexicaux ne peuvent pas être utilisés car le niveau diégétique dans lequel ils sont interprétés ne contient pas de paramètres d'agent et d'interlocuteur, contrairement aux contextes de communication linguistique; en revanche, la diégèse du discours indirect libre contient les paramètres de monde, de lieu et de temps, ce qui permet l'utilisation des indexicaux temporels (maintenant, demain) et locatifs (ici) dans ce mode. En d'autres termes, le contexte de la diégèse dans lequel le discours indirect libre est interprété est un contexte impropre, au sens de Predelli (1998).
Detección de violencia machista entre las mujeres atendidas por tentativa autolítica en un servicio de urgencias.
Creators: name: Merodio Ruiz, Igor
name: Cobo, Jesús
name: Canta López, Elena
name: Corrigüelas Marín, Mónica
name: Santiago Barragán, Ángel María
name: Camposo Montesinos, María Carmen
name: Rubio García, Alejandra
name: Llauradó Igual, Laura
name: Cosculluela Pérez, Albert
name: Aguayo Navarro, Raquel
name: Castro Pérez, Lourdes
name: Molla Robles, Paula
name: Muñoz Martínez, María Teresa
name: Palao Vidal, Diego J.
name: Granero Lázaro, Albert
Publisher: name: Psicosomàtica y Psiquiatría
Year: 2024

description: Psicosomàtica y Psiquiatría, Núm. 28 (2024): enero-febrero-marzo
3D-принтер в академічній бібліотеці: з досвіду роботи Наукової бібліотеки Національного університету "Києво-Могилянська академія"
Creators: name: Nazarovets, Serhii
Publisher: name: figshare
Year: 2017
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: The article describes the experience of the use of 3D-prin-ters in the National University of Kyiv-Mohyla Academy Library, its implementation in the educational process of the university. The establishment of such new library services using 3D-prin-ting technology can be easily repeated in other academic libraries.
Logique, sémantique, pragmatique
Creators: name: Moeschler, Jacques
Publisher: name: Université de Genève
Year: 2019
Subjects: info:eu-repo/classification/ddc/410
Connecteurs
Négation
Interface sémantique-pragmatique
Signification conceptuelle et procédurale
Présupposition
Implicature
Explicature

description: Cet article donne une synthèse du cadre théorique du projet LogPrag, plus spécifiquement des relations entre la sémantique des mots logiques et leur pragmatique. Il discute du cadre théorique dans lequel une telle relation peut être explicitée, et aussi des raisons pour lesquelles l'enrichissement pragmatique des connecteurs logiques et de la négation est requis. Nous défendrons l'hypothèse selon laquelle la signification linguistique correspond à la signification logique. La motivation principale est la capacité dérivationnelle d'une telle sémantique, complétée par une pragmatique inférentielle. Nous montrerons qu'une telle sémantique a un autre avantage : elle permet de donner une image précise de l'interface sémantique-pragmatique, et des raisons pour lesquelles la sémantique logique doit être complétée par une pragmatique inférentielle. Nous aborderons enfin la relation entre signification conceptuelle vs procédurale et type de significations sémantiques et pragmatiques.
Additional file 1: of Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC
Creators: name: Wei, Yongyue
name: Liang, Junya
name: Zhang, Ruyang
name: Guo, Yichen
name: Shen, Sipeng
name: Su, Li
name: Lin, Xihong
name: Moran, Sebastian
name: Helland, Ăslaug
name: BjaanĂŚs, Maria
name: Karlsson, Anna
name: Planck, Maria
name: Esteller, Manel
name: Fleischer, Thomas
name: Staaf, Johan
name: Zhao, Yang
name: Chen, Feng
name: Christiani, David
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Figure S1. Quality control processes for DNA methylation chip data. Quality control measures and exclusion criteria as applied to Harvard, Spain, Norway, Sweden, and The Cancer Genome Atlas (TCGA) sample cohorts. (PDF 642 kb)