cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Multiwavelength studies of MHD waves in the solar chromosphere: An overview of recent results
Creators: name: Jess, D. B.
name: Morton, R. J.
name: Verth, G.
name: Fedun, V.
name: Grant, S. D. T.
name: Giagkiozis, I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The chromosphere is a thin layer of the solar atmosphere that bridges the relatively cool photosphere and the intensely heated transition region and corona. Compressible and incompressible waves propagating through the chromosphere can supply significant amounts of energy to the interface region and corona. In recent years an abundance of high-resolution observations from state-of-the-art facilities have provided new and exciting ways of disentangling the characteristics of oscillatory phenomena propagating through the dynamic chromosphere. Coupled with rapid advancements in magnetohydrodynamic wave theory, we are now in an ideal position to thoroughly investigate the role waves play in supplying energy to sustain chromospheric and coronal heating. Here, we review the recent progress made in characterising, categorising and interpreting oscillations manifesting in the solar chromosphere, with an impetus placed on their intrinsic energetics.
description: 48 pages, 25 figures, accepted into Space Science Reviews
Substantial increase in acceleration potential of pyroelectric crystals
Creators: name: Shafroth, S. M.
name: Lynam, S. M.
name: Tornow, W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We report on a substantial increase in the acceleration potential achieved with a LiTaO3 pyroelectric crystal. With a single 2.5 cm diameter and 2.5 cm long z-cut crystal without electric field-enhancing nanotip we produced positive ion beams with maximal energies between 300 and 310 keV during the cooling phase when the crystal was exposed to 5 mTorr of deuterium gas. These values are about a factor of 2 larger than previously obtained with single pyroelectric crystals.
(2837) Annie Lee
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Read online: When No One Is Watching by Alyssa Cole
Creators: name: Tolentino
Publisher: name: Zenodo
Year: 2024

description: When No One Is Watching by Alyssa Cole

 

 

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When No One Is Watching

Alyssa Cole

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ISBN: 9780063111615

Publisher: HarperCollins Publishers

 

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Neutrino pair and gamma beams from circulating excited ions
Creators: name: Yoshimura, M.
name: Sasao, N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We propose a new method of producing neutrino pair beam that consists of a mixture of neutrinos and anti-neutrinos of all flavors. The idea is based on a coherent neutrino pair emission from excited ions in circular motion. High energy gamma ray much beyond the keV range may also be produced by a different choice of excited level.
description: 15 pages, 5 figures.Previous version v1 separated into two papers. This revision v2 is on neutrino pair and gamma production (essentially the same content as in the corresponding parts of v1), and the next paper soon to be updated contains extended and corrected results on neutrino oscillation experiments
DOWNLOAD [PDF] {EPUB} Learn Your Lesson by Kandi Steiner
Creators: name: Tate
Publisher: name: Zenodo
Year: 2024

description: Learn Your Lesson by Kandi Steiner

 

 

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Learn Your Lesson

Kandi Steiner

Page: 470

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ISBN: 9781960649263

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Figure S4 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Eukaryotic microbes have three primary mechanisms for obtaining nutrients and energy: phagotrophy, photosynthesis and osmotrophy. Traits associated with the latter two functions arose independently multiple times in the eukaryotes. Fungi successfully coupled osmotrophy with filamentous growth, similar traits are also manifested in the Pseudofungi (oomycetes and hyphochytriomycetes). Both the Fungi and the Pseudofungi encompass a diversity of plant and animal parasites. Genome-sequencing efforts have focused on host-associated microbes (mutualistic symbionts or parasites), providing limited comparisons with free-living relatives. Here we report the first draft genome sequence of a hyphochytriomycete ‘pseudofungus’; Hyphochytrium catenoides. Using phylogenomic approaches, we identify genes of recent viral ancestry, with related viral derived genes also present on the genomes of oomycetes, suggesting a complex history of viral coevolution and integration across the Pseudofungi. H. catenoides has a complex life cycle involving diverse filamentous structures and a flagellated zoospore with a single anterior-tinselate flagellum. We use genome comparisons, drug sensitivity analysis and high-throughput culture arrays to investigate the ancestry of oomycete/pseudofungal characteristics and metabolic traits, demonstrating that many of the genetic features associated with pathogenic traits evolved specifically within the oomycete radiation. Comparative genomics also identified differences in the repertoire of genes associated with filamentous growth between the Fungi and the Pseudofungi, including differences in vesicle trafficking systems, cell-wall synthesis pathways and motor protein repertoire, demonstrating that unique cellular systems underpinned the convergent evolution of filamentous osmotrophic growth in these two eukaryotic groups.
Comparison of Buoy-Mounted and Bottom-Moored ADCP Performance at Gray’s Reef
Creators: name: Edwards, Catherine R.
name: Seim, Harvey E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Simultaneous ADCP profile measurements are compared over a 2-month period in late 2003. One set of measurements comes from a National Data Buoy Center (NDBC) buoy-mounted ADCP, the other from a bottom-mounted, upward-looking ADCP moored roughly 500 m from the buoy. The study was under- taken to evaluate the proficiency of an experimental configuration by NDBC; unfortunately, the ADCP was not optimally configured. The higher temporally and vertically resolved bottom-mounted ADCP data are interpolated in time and depth to match the buoy-mounted ADCP measurements. It is found that the two ADCP measurements are significantly different. The buoy-mounted measurements are affected by high- frequency (10 h period) noise that is vertically coherent throughout the profiles. This noise results in autospectra that are essentially white, unlike the classic red spectra formed from the bottom-mounted ADCP observations. The spectra imply a practical noise floor of 0.045 m s1 for the buoy-mounted system. Contamination by surface waves is the likely cause of this problem. At tidal frequencies the buoy-mounted system underestimates major axis tidal current magnitude by 10%-40%; interference from the buoy chain and/or fish or plankton are considered the most likely cause of the bias. The subtidal velocity field (periods greater than 40 h) is only partially captured; the correlation coefficient for the east-west current is 0.49 and for the north-south current is 0.64.
(2832) John William Mountain
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 1 of The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial analysis
Creators: name: Schmidt, Chris A.
name: Cromwell, Elizabeth A.
name: Hill, Elex
name: Donkers, Katie M.
name: Schipp, Megan F.
name: Johnson, Kimberly B.
name: Pigott, David M.
name: Hay, Simon I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1: Supplementary Appendix. This file contains a GATHER compliance checklist, a list of data sources used in the present analysis, and further details of the analytical methodology and results.
Complex EOF Analysis as a Method to Separate Barotropic and Baroclinic Velocity Structure in Shallow Water
Creators: name: Edwards, Catherine R.
name: Seim, Harvey E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Defining the vertical depth average of measured currents to be barotropic is a widely used method of separating barotropic and baroclinic tidal currents in the ocean. Away from the surface and bottom bound- ary layers, depth-averaging measured velocity is an excellent estimate of barotropic tidal flow, and internal tidal dynamics can be well represented by the difference between the measured currents and their depth average in the vertical. However, in shallow and/or energetic tidal environments such as the shelf of the South Atlantic Bight (SAB), bottom boundary layers can occupy a significant fraction of the water column, and depth averaging through the bottom boundary layer can overestimate the barotropic current by several tens of centimeters per second near bottom. The depth-averaged current fails to capture the bottom boundary layer structure associated with the barotropic tidal signal, and the resultant estimate of baroclinic tidal currents can mimic a bottom-trapped internal tide. Complex empirical orthogonal function (CEOF) analysis is proposed as a method to retain frictional effects in the estimate of the barotropic tidal currents and allow an improved determination of the baroclinic currents. The method is applied to a midshelf region of the SAB dominated by tides and friction to quantify the effectiveness of CEOF analysis to represent internal structure underlying a strong barotropic signal in shallow water. Using examples of synthesized and measured data, EOF estimates of the barotropic and baroclinic modes of motion are compared to those made using depth averaging. The estimates of barotropic tidal motion using depth-averaging and CEOF methods produce conflicting predictions of the frequencies at which there is meaningful baroclinic variability. The CEOF method preserves the frictional boundary layer as part of the barotropic tidal current structure in the gravest mode, providing a more accurate representation of internal structure in higher modes. The application of CEOF techniques to isolate internal structure co-occurring with highly energetic tidal dynamics in shallow water is a significant test of the method. Successful separation of barotropic and baroclinic modes of motion suggests that, by fully capturing the effects of friction associated with the barotropic tide, CEOF analysis is a viable technique to facilitate examination of the internal tide in similar environments.
Figure S6 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides.
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Eukaryotic microbes have three primary mechanisms for obtaining nutrients and energy: phagotrophy, photosynthesis and osmotrophy. Traits associated with the latter two functions arose independently multiple times in the eukaryotes. Fungi successfully coupled osmotrophy with filamentous growth, similar traits are also manifested in the Pseudofungi (oomycetes and hyphochytriomycetes). Both the Fungi and the Pseudofungi encompass a diversity of plant and animal parasites. Genome-sequencing efforts have focused on host-associated microbes (mutualistic symbionts or parasites), providing limited comparisons with free-living relatives. Here we report the first draft genome sequence of a hyphochytriomycete ‘pseudofungus’; Hyphochytrium catenoides. Using phylogenomic approaches, we identify genes of recent viral ancestry, with related viral derived genes also present on the genomes of oomycetes, suggesting a complex history of viral coevolution and integration across the Pseudofungi. H. catenoides has a complex life cycle involving diverse filamentous structures and a flagellated zoospore with a single anterior-tinselate flagellum. We use genome comparisons, drug sensitivity analysis and high-throughput culture arrays to investigate the ancestry of oomycete/pseudofungal characteristics and metabolic traits, demonstrating that many of the genetic features associated with pathogenic traits evolved specifically within the oomycete radiation. Comparative genomics also identified differences in the repertoire of genes associated with filamentous growth between the Fungi and the Pseudofungi, including differences in vesicle trafficking systems, cell-wall synthesis pathways and motor protein repertoire, demonstrating that unique cellular systems underpinned the convergent evolution of filamentous osmotrophic growth in these two eukaryotic groups.
LA HEREDERA DEL MAR JUAN FRANCISCO FERRANDIZ ePub gratis
Creators: name: Owens
Publisher: name: Zenodo
Year: 2024

description: LA HEREDERA DEL MAR de JUAN FRANCISCO FERRANDIZ

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LA HEREDERA DEL MAR

JUAN FRANCISCO FERRANDIZ

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788425366871

Editorial: GRIJALBO

Año de edición: 2024

 

 

 

 

 

Ebook para descarga de conocimiento general LA HEREDERA DEL MAR 9788425366871 (Spanish Edition)

 

Overview
(2833) Elizabeth [Mountain]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(2829) John Laycock
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Table S6 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides.
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Results and primers used to confirm viral presence in the H. catenoides genome
A principal possibility for computer investigation of evolution of dynamical systems with independent on time accuracy
Creators: name: Gurzadyan, V. G.
name: Harutyunyan, V. V.
name: Kocharyan, A. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Extensive N-body simulations are among the key means for the study of numerous astrophysical and cosmological phenomena, so various schemes are developed for possibly higher accuracy computations. We demonstrate the principal possibility for revealing the evolution of a perturbed Hamiltonian system with an accuracy independent on time. The method is based on the Laplace transform and the derivation and analytical solution of an evolution equation in the phase space for the resolvent and using computer algebra.
description: Eur Phys Journ C (in press), to match the version to appear, 7 pages, 3 figs
Fractal analysis for classification of breast carcinoma in optical coherence tomography
Creators: name: Hunt, John P.
name: Oldenburg, Amy L.
name: Sullivan, Amanda C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The accurate and rapid assessment of tumor margins during breast cancer resection using optical coherence tomography (OCT) has the potential to reduce patient risk. However, it is difficult to subjectively distinguish cancer from normal fibroglandular stromal tissues in OCT images, and an objective measure is needed. In this initial study, we investigate the potential of a one-dimensional fractal box-counting method for cancer classification in OCT. We computed the fractal dimension, a measure of the self-similarity of an object, along the depth axis of 44 ultrahigh-resolution OCT images of human breast tissues obtained from 4 cancer patients. Correlative histology was employed to identify distinct regions of adipose, stroma, and cancer in the OCT images. We report that the fractal dimension of stroma is significantly higher than that of cancer (P < 10(-5), t-test). Furthermore, by adjusting the cutoff values of fractal dimension between cancer, stroma, and adipose tissues, sensitivities and specificities of either 82.4% and 88.9%, or 88.2% and 81.5%, are obtained, respectively, for cancer classification. The use of fractal analysis with OCT could potentially provide automated identification of tumor margins during breast-sparing surgery.
Review of recent developments in stimulated emission depletion microscopy: applications on cell imaging
Creators: name: Wang, Gufeng
name: Neupane, Bhanu
name: Ligler, Frances S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Stimulated emission depletion (STED) microscopy is one type of far-field optical technique demonstrated to provide subdiffraction resolution. STED microscopy utilizes a donut-shaped depletion beam to limit the probe volume to be much smaller than a diffraction-limited spot. Resolutions as small as a few tens of nanometers laterally are reported for cell analysis. The different versions of STED microscopes are described and contrasted in terms of their applicability for biological imaging. Finally, we suggest likely avenues for improving the performance and increasing the utility of STED microscopy.
EL DESPERTAR DE LA MAGIA leer pdf
Creators: name: Parker
Publisher: name: Zenodo
Year: 2024

description: EL DESPERTAR DE LA MAGIA de MARALUCK

Descargar eBook gratis ➡ Link

Ficha técnica

EL DESPERTAR DE LA MAGIA

MARALUCK

Número de páginas: 160

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788402428882

Editorial: BRUGUERA

Año de edición: 2023

 

 

 

 

 

Descarga gratuita de google books EL DESPERTAR DE LA MAGIA 9788402428882 de MARALUCK

 

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Descubre la magia que te rodea de la mano de Maraluck, pagana, ocultista y bruja experta en MAGIA ÍBERA Desde que soy pagana y practicante de brujería siempre he intentado encontrar mi sitio. Con el tiempo, entendí que el lugar en el que vivimos, nuestro territorio, es parte de nosotros. Investigue a nuestros ancestros íberos y no tarde en enamorarme de la manera que tenían de entender el mundo y el territorio, su forma de proceder ante los actos mágicos y, por supuesto, de su brujería. Porque, sí, la brujería existe desde que el ser humano tiene uso de razón. Aquí encontrarásun repaso por la cultura íbera, su panteón de dioses, magia gráfica, ritos antiguos y cómo podemos integrarlos en nuestra práctica de la magia cotidiana. Te doy la bienvenida a la magia íbera.
Anaphase onset does not require the microtubule-dependent depletion of kinetochore and centromere-binding proteins
Creators: name: Sharma, Nitin
name: Canman, Julie C.
name: Fang, Guowei
name: Salmon, E. D.
name: Shannon, Katie B.
name: Straight, Aaron
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Spindle checkpoint proteins, such as Mad2 and BubR1, and the motors dynein/dynactin and CENP-E usually leave kinetochores prior to anaphase onset by microtubule-dependent mechanisms. Likewise, 'chromosome passenger proteins' including INCENP are depleted from the centromeres after anaphase onset and then move to the midzone complex, an event that is essential for cytokinesis. Here we test whether the cell cycle changes that occur at anaphase onset require or contribute to the depletion of kinetochore and centromere proteins independent of microtubules. This required the development of a novel non-antibody method to induce precocious anaphase onset in vivo by using a bacterially expressed fragment of the spindle checkpoint protein Mad1 capable of activating the APC/C, called GST-Mad1F10. By injecting PtK1 cells in nocodazole with GST-Mad1F10 and processing the cells for immunofluorescence microscopy after anaphase sister chromatid separation in nocodazole we found that Mad2, BubR1, cytoplasmic dynein, CENP-E and the 3F3/2 phosphoepitope remain on kinetochores. Thus depletion of these proteins (or phosphoepitope) at kinetochores is not required for anaphase onset and anaphase onset does not produce their depletion independent of microtubules. In contrast, both microtubules and anaphase onset are required for depletion of the 'chromosome passenger' protein INCENP from centromeres, as INCENP does not leave the chromosomes prior to anaphase onset in the presence or absence of microtubules, but does leave the centromeres after anaphase onset in the presence of microtubules.
(2831) George Quinney Mountain
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
PTP-PEST controls motility through regulation of Rac1
Creators: name: Burridge, Keith
name: Sastry, Sarita K.
name: Schaller, Michael D.
name: Lyons, Patrick D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The cytoplasmic protein tyrosine phosphatase, PTP-PEST, associates with the focal adhesion proteins p130cas and paxillin and has recently been implicated in cell migration. In this study, we investigated the mechanism by which PTP-PEST regulates this phenomenon. We find that PTP-PEST is activated in an adhesion-dependent manner and localizes to the tips of membrane protrusions in spreading fibroblasts. We show that the catalytic activity of PTP-PEST is a key determinant for its effects on motility. Overexpression of PTP-PEST, but not a catalytically inactive form, impairs haptotaxis, cell spreading and formation of membrane protrusions in CHOK1 cells. In addition, overexpression of PTP-PEST in Rat1 fibroblasts perturbs membrane ruffling and motility in response to PDGF stimulation. The expression level of PTP-PEST modulates the activity of the small GTPase, Rac1. PTP-PEST overexpression suppresses activation of Rac1 in response to both integrin-mediated adhesion or growth factor stimulation. In contrast, fibroblasts that lack PTP-PEST expression show enhanced Rac1 activity. Co-expression of constitutively active Rac1 with PTP-PEST overcomes the inhibition of cell spreading and migration indicating that PTP-PEST acts by antagonizing Rac1 activation. Our data suggest a model in which PTP-PEST is activated by integrins and localized to regions where it can control motile events at the leading edge through inhibition of the small GTPase Rac1.
Transient dynamics in the Anderson-Holstein model with interfacial screening
Creators: name: Perfetto, E.
name: Stefanucci, G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the combined effects of electron-phonon coupling and dot-lead repulsion in the transport properties of the Anderson-Holstein model. We employ a recently proposed nonperturbative method to calculate the transient response of the system. By varying the initial conditions for the time propagation the current exhibits transient oscillations of different nature. We are able to disentangle two dynamical processes, namely the local charge rearrangement due to the dot-lead contacting and the establishment of the nonequilbrium many-body state due to the application of the external bias. These processes involve either Franck-Condon excitations or transitions between the resonant level and the Fermi energy of the leads.
description: 6 pages, 6 figures
Figure S8 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides.
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Eukaryotic microbes have three primary mechanisms for obtaining nutrients and energy: phagotrophy, photosynthesis and osmotrophy. Traits associated with the latter two functions arose independently multiple times in the eukaryotes. Fungi successfully coupled osmotrophy with filamentous growth, similar traits are also manifested in the Pseudofungi (oomycetes and hyphochytriomycetes). Both the Fungi and the Pseudofungi encompass a diversity of plant and animal parasites. Genome-sequencing efforts have focused on host-associated microbes (mutualistic symbionts or parasites), providing limited comparisons with free-living relatives. Here we report the first draft genome sequence of a hyphochytriomycete ‘pseudofungus’; Hyphochytrium catenoides. Using phylogenomic approaches, we identify genes of recent viral ancestry, with related viral derived genes also present on the genomes of oomycetes, suggesting a complex history of viral coevolution and integration across the Pseudofungi. H. catenoides has a complex life cycle involving diverse filamentous structures and a flagellated zoospore with a single anterior-tinselate flagellum. We use genome comparisons, drug sensitivity analysis and high-throughput culture arrays to investigate the ancestry of oomycete/pseudofungal characteristics and metabolic traits, demonstrating that many of the genetic features associated with pathogenic traits evolved specifically within the oomycete radiation. Comparative genomics also identified differences in the repertoire of genes associated with filamentous growth between the Fungi and the Pseudofungi, including differences in vesicle trafficking systems, cell-wall synthesis pathways and motor protein repertoire, demonstrating that unique cellular systems underpinned the convergent evolution of filamentous osmotrophic growth in these two eukaryotic groups.
Additional file 1 of Development and validation of the body image scale for youth (BISY)
Creators: name: Jalali-Farahani, Sara
name: Amiri, Parisa
name: Zarani, Fariba
name: Zayeri, Farid
name: Azizi, Fereidoun
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Cardiology

description: Additional file 1. The BISY and its scoring procedure.
Coupling membrane protrusion and cell adhesion
Creators: name: DeMali, Kris A.
name: Burridge, Keith
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: The ability of cells to extend cell membranes is central to numerous biological processes, including cell migration, cadherin-mediated junction formation and phagocytosis. Much attention has been focused on understanding the signals that trigger membrane protrusion and the architecture of the resulting extension. Similarly, cell adhesion has been extensively studied, yielding a wealth of information about the proteins involved and how they signal to the cytoplasm. Although we have learned much about membrane protrusion and cell adhesion, we know less about how these two processes are coupled. Traditionally it has been thought that they are linked by the signaling pathways they employ - for example, those involving Rho family GTPases. However, there are also physical links between the cellular machineries that mediate cell adhesion and membrane protrusion, such as vinculin.
A Study of Academic Performance Factors of Prathom Sueksa Six Students
Creators: name: Nuthathai Kanthapong
Publisher: name: DR.KEN Institute of Academic Development and Promotion.
Year: 2023
Subjects: Academic Performance
Exploratory Factor Analysis
Prathom Sueksa Six Students

description: Interdisciplinary Academic and Research Journal, 3, 1, 553-572
Figure S6 from Comparative genomic analysis of the ‘psuedofungus’ Hyphochytrium catenoides
Creators: name: Leonard, Guy
name: Labarre, Aurélie
name: Milner, David S.
name: Monier, Adam
name: Soanes, Darren
name: Wideman, Jeremy G.
name: Maguire, Finlay
name: Stevens, Sam
name: Sain, Divya
name: Grau-Bove, Xavier
name: Arnau Sebe-Pedros
name: Stajich, Jason E.
name: Paszkiewicz, Konrad
name: Brown, Matthew W.
name: Hall, Neil
name: Wickstead, Bill
name: Richards, Thomas A.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Eukaryotic microbes have three primary mechanisms for obtaining nutrients and energy: phagotrophy, photosynthesis and osmotrophy. Traits associated with the latter two functions arose independently multiple times in the eukaryotes. Fungi successfully coupled osmotrophy with filamentous growth, similar traits are also manifested in the Pseudofungi (oomycetes and hyphochytriomycetes). Both the Fungi and the Pseudofungi encompass a diversity of plant and animal parasites. Genome-sequencing efforts have focused on host-associated microbes (mutualistic symbionts or parasites), providing limited comparisons with free-living relatives. Here we report the first draft genome sequence of a hyphochytriomycete ‘pseudofungus’; Hyphochytrium catenoides. Using phylogenomic approaches, we identify genes of recent viral ancestry, with related viral derived genes also present on the genomes of oomycetes, suggesting a complex history of viral coevolution and integration across the Pseudofungi. H. catenoides has a complex life cycle involving diverse filamentous structures and a flagellated zoospore with a single anterior-tinselate flagellum. We use genome comparisons, drug sensitivity analysis and high-throughput culture arrays to investigate the ancestry of oomycete/pseudofungal characteristics and metabolic traits, demonstrating that many of the genetic features associated with pathogenic traits evolved specifically within the oomycete radiation. Comparative genomics also identified differences in the repertoire of genes associated with filamentous growth between the Fungi and the Pseudofungi, including differences in vesicle trafficking systems, cell-wall synthesis pathways and motor protein repertoire, demonstrating that unique cellular systems underpinned the convergent evolution of filamentous osmotrophic growth in these two eukaryotic groups.
Merotelic kinetochore orientation occurs frequently during early mitosis in mammalian tissue cells and error correction is achieved by two different mechanisms
Creators: name: Moree, Ben
name: Canman, Julie C.
name: Cimini, Daniela
name: Salmon, E. D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Merotelic kinetochore orientation is an error that occurs when a single kinetochore becomes attached to microtubules from two spindle poles rather than just to one pole. We obtained the first evidence that merotelic kinetochore orientation occurs very frequently during early mitosis in mammalian tissue cells and that two different correction mechanisms are critical for accurate chromosome segregation in cells possessing bipolar spindles and unperturbed chromosomes. Our data show that about 30% of prometaphase PtK1 cells possess one or more merotelically oriented kinetochores. This frequency is increased to over 90% in cells recovering from a nocodazole-induced mitotic block. A delay in establishing spindle bipolarity is responsible for the high frequency of merotelic orientations seen in cells recovering from nocodazole, but not in untreated cells. The frequency of anaphase cells with merotelically oriented lagging chromosomes is 1% in untreated cells and 18% in cells recovering from nocodazole. Prolonging metaphase by 2 hours reduced the frequency of anaphase cells with lagging chromosomes both for untreated and for nocodazole-treated cells. Surprisingly, anaphase lagging chromosomes represented a very small fraction of merotelic kinetochore orientations present in late metaphase. Our data indicate that two correction mechanisms operate to prevent chromosome missegregation due to merotelic kinetochore orientation. The first, a pre-anaphase correction mechanism increases the ratio of kinetochore microtubules attached to the correct versus incorrect pole and might eventually result in kinetochore reorientation before anaphase onset. The increase in microtubule ratio to opposite poles is the groundwork for a second mechanism, active in anaphase, that promotes the segregation of merotelically oriented chromosomes to the correct pole.
Download PDF Empire Falling: A Twilight Wars Novel by Robbie MacNiven
Creators: name: Keiser
Publisher: name: Zenodo
Year: 2024

description: Empire Falling: A Twilight Wars Novel by Robbie MacNiven

 

 

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Empire Falling: A Twilight Wars Novel

Robbie MacNiven

Page: 352

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MAP kinases and cell migration
Creators: name: Huang, Cai
name: Jacobson, Ken
name: Schaller, Michael D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Recent studies have demonstrated that mitogen-activated protein kinases (MAPKs), including Jun N-terminus kinase (JNK), p38 and Erk, play crucial roles in cell migration. JNK, for example, regulates cell migration by phosphorylating paxillin, DCX, Jun and microtubule-associated proteins. Studies of p38 show that this MAPK modulates migration by phosphorylating MAPK-activated protein kinase 2/3 (MAPKAP 2/3), which appears to be important for directionality of migration. Erk governs cell movement by phosphorylating myosin light chain kinase (MLCK), calpain or FAK. Thus, the different kinases in the MAPK family all seem able to regulate cell migration but by distinct mechanisms.
(2826) Kenneth Sporswood Jones
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Phase transitions in the q-voter model with noise on a duplex clique
Creators: name: Chmiel, Anna
name: Sznajd-Weron, Katarzyna
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: We study a nonlinear q-voter model with stochastic noise, interpreted in the social context as independence, on a duplex network. To study the role of the multi-levelness we propose three methods of transferring the model from a mono- to a multiplex network. They take into account two criteria -- one related to the status of independence (LOCAL vs. GLOBAL) and one related to peer pressure (AND vs. OR). In order to examine the influence of the presence of more than one level in the social network, we perform simulations on a particularly simple multiplex -- a duplex clique, which consists of two fully overlapped complete graphs (cliques). Solving numerically the rate equation and simultaneously conducting Monte Carlo simulations, we provide evidence that even a simple rearrangement into a duplex topology may lead to significant changes in the observed behavior. However, qualitative changes in the phase transitions can be observed for only one of the considered rules -- LOCAL&AND. For this rule the phase transition becomes discontinuous for q=5, whereas for a monoplex such a behavior is observed for q=6. Interestingly, only this rule admits construction of realistic variants of the model, in line with recent social experiments.
description: 11 pages,13 figures