cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Untitled
Creators: name: Young, Tim
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Selection on metabolic pathway function in the presence of mutation-selection-drift balance leads to rate-limiting steps that are not evolutionarily stable
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: Metabolic pathway evolution
Systems biology
Population genetics

description: © 2013 van Poelgeest et al. Background: While commonly assumed in the biochemistry community that the control of metabolic pathways is thought to be critical to cellular function, it is unclear if metabolic pathways generally have evolutionarily stable rate limiting (flux controlling) steps. Results: A set of evolutionary simulations using a kinetic model of a metabolic pathway was performed under different conditions to evaluate the evolutionary stability of rate limiting steps. Simulations used combinations of selection for steady state flux, selection against the cost of molecular biosynthesis, and selection against the accumulation of high concentrations of a deleterious intermediate. Two mutational regimes were used, one with mutations that on average were neutral to molecular phenotype and a second with a preponderance of activity-destroying mutations. The evolutionary stability of rate limiting steps was low in all simulations with non-neutral mutational processes. Clustering of parameter co-evolution showed divergent inter-molecular evolutionary patterns under different evolutionary regimes. Conclusions: This study provides a null model for pathway evolution when compensatory processes dominate with potential applications to predicting pathway functional change. This result also suggests a possible mechanism in which studies in statistical genetics that aim to associate a genotype to a phenotype assuming independent action of variants may be mis-specified through a mis-characterization of the link between individual gene function and pathway function. A better understanding of the genotype-phenotype map has potential applications in differentiating between compensatory changes and directional selection on pathways as well as detecting SNPs and fixed differences that might have phenotypic effects.
David Lindsay's A voyage to Arcturus ; allegorical dream fantasy as a literary mode
Creators: name: Schofield, Jack
Publisher: name: University of British Columbia
Year: 2011

description: David Lindsay's A Voyage to Arcturus must be read as an allegorical dream fantasy for its merit to be correctly discerned. Lindsay's central themes are introduced in a study of the man and his work. (Ch. 1). These themes are found to be common in allegorical dream fantasy, the phenomenological background of which is established (Ch. 2). A distinction can then be drawn between fantasy and romance, so as to define allegorical dream fantasy as a literary mode (Ch. 3). After the biographical, theoretical and literary backgrounds of A Voyage have been established in the first three chapters, the second three chapters explicate the structure of the book as an allegorical dream fantasy. Finally, the dichotomies which have been found in Lindsay (between Lloyd's underwriter and visionary dreamer), between the dream and the real world, between fantasy and romance, are found to be unified by Norman N. Holland's theory of literature as transformation
Superstring-inspired supergravity as the universal source of inflation and quintessence
Creators: name: Gates, S. James
name: Ketov, Sergei V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We prove (in superspace) the equivalence between the higher-derivative N=1 supergravity, defined by a holomorphic function F of the chiral scalar curvature superfield, and the standard theory of a chiral scalar superfield with a chiral superpotential W, coupled to the (minimal) Poincare supergravity in four spacetime dimensions. The relation between the holomorphic functions F and W is found. It can be used as the technical framework for the possible scenario unifying the early Universe inflation and the present Universe acceleration. We speculate on the possible origin of our model as the effective supergravity generated by quantum superstrings, with a dilaton-axion field as the leading field component of the chiral superfield.
description: 12 pages, Latex, no figures; some corrections in the equations of sect.8, more references added
ВСТРЕЧИ НА СВЕЖЕМ ВОЗДУХЕ: ПО ОДИНОЧКЕ И ВМЕСТЕ
Creators: name: Паркер-Белл Барбара
Publisher: name: Экопоэзис: экогуманитарные теория и практика
Year: 2021
Subjects: ЭКО-АРТ-ТЕРАПИЯ
ПРИРОДА
ПСИХОЛОГИЧЕСКАЯ САМОПОМОЩЬ
САМОРЕГУЛЯЦИЯ

description: Статья подготовлена на основе доклада доктора Паркер-Белл, представленного на 24-ой ежегодной конференции «Арт-терапия сегодня» 7-8 мая 2021 г. Представлен опыт проведения занятий изобразительным искусством, посвященных развитию навыков психологической саморегуляции у выпускников арт-терапии в Университете штата Флорида во время пандемии COVID-19. Из-за ограничений, связанных с необходимостью проведения онлайн-обучения в период пандемии, реализация мастер-класса в учебной аудитории оказалась сложной задачей. Поэтому было решено использовать эко-арт-терапевтический формат обучения, проводя занятия на свежем воздухе на территории и в окрестностях Таллахасси. В статье представлены работы и размышления преподавателя и студентов, касающиеся ценности занятий изобразительным искусством на свежем воздухе с целью психопрофилактики. Темы, которые были затронуты в результате размышлений, включали повышение осведомленности о полезности взаимодействия с природой для снижения стресса, восстановление связи с природой и другими людьми, а также переживание положительных эмоций, связанных с созерцанием природы и работой с натуральными материалами.
Reward sensitivity enhances ventrolateral prefrontal cortex activation during free choice
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: choice
cognitive control
perceived control
striatum

description: © 2016 Cho, Smith and Delgado. Expressing one's preference via choice can be rewarding, particularly when decisions are voluntarily made as opposed to being forced. An open question is whether engaging in choices involving rewards recruits distinct neural systems as a function of sensitivity to reward. Reward sensitivity is a trait partly influenced by the mesolimbic dopamine system, which can impact an individual's neural and behavioral response to reward cues. Here, we investigated how reward sensitivity contributes to neural activity associated with free and forced choices. Participants underwent a simple decision-making task, which presented free- or forced-choice trials in the scanner. Each trial presented two cues (i.e., points or information) that led to monetary reward at the end of the task. In free-choice trials, participants were offered the opportunity to choose between different reward cues (e.g., points vs. information), whereas forced-choice trials forced individuals to choose within a given reward cue (e.g., information vs. information, or points vs. points). We found enhanced ventrolateral prefrontal cortex (VLPFC) activation during free choice compared to forced choice in individuals with high reward sensitivity scores. Next, using the VLPFC as a seed, we conducted a PPI analysis to identify brain regions that enhance connectivity with the VLPFC during free choice. Our PPI analyses on free vs. forced choice revealed increased VLPFC connectivity with the posterior cingulate and precentral gyrus in reward sensitive individuals. These findings suggest reward sensitivity may recruit attentional control processes during free choice potentially supporting goal-directed behavior and action selection.
Design, analysis, and testing of a microdot apodizer for the Apodized Pupil Lyot Coronagraph. II. The dot size impact. (Research Note)
Creators: name: Martinez, P.
name: Dorrer, C.
name: Kasper, M.
name: Boccaletti, A.
name: Dohlen, K.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The Apodized Pupil Lyot Coronagraph (APLC) is a promising coronagraphic device for direct exoplanets detection on the European-Extremely Large Telescope. We present new near-IR laboratory results using binary apodizers -- the so-called microdots apodizer -- which represent a very attractive and advantageous solution for the APLC. Microdots apodizers introduce high-frequency noise whose characteristics depend on the pixel size. The aim of this work is to characterize the impact of the pixel size on the coronagraphic image. Estimation of both the noise intensity and its localization in the field of view is the objective of this study. Stray-light diffraction introduced by the finite pixel size was measured during experiment. Intensity decreases, and radial distance increases, when the pixel size gets smaller. The physical properties of these microdots apodizers have been demonstrated in laboratory. The microdots apodizer is a suitable solution for any coronagraph using pupil amplitude apodization if properly designed.
description: Accepted in Astronomy and Astrophysics 2009
ГОРОД ЕЛЕНЫ: ИМПУЛЬС ДЛЯ НОВОГО НАЧАЛА
Creators: name: Харрисон Ньютон
Publisher: name: Экопоэзис: экогуманитарные теория и практика
Year: 2021
Subjects: СЕТЬ ЖИЗНИ
ЭКОЛОГИЧЕСКОЕ ГОРОДСКОЕ ОБРАЗОВАНИЕ
БИОРАЗНООБРАЗИЕ
ШЕСТОЕ МАССОВОЕ ВЫМИРАНИЕ
ЭКОПОЭЗИС
АУТОПОЭЗИС

description: Один из пионеров и лидеров движения эко-арта, Ньютон Харрисон представляет проект создания экопоселения, органично связанного с глобальной «сетью жизни». Наиболее вероятной территорией для реализации данного проекта автору представляется территория Российской Федерации. Создание подобных поселений ставит своей целью ответить на вопрос: каким образом может быть организована жизнедеятельность человека в условиях небольших общин при повышении температуры на Сибирской равнине, которая будет возможным местом поселения групп беженцев, прибывающих как изнутри Российской Федерации, так и извне.
Supplementary document for Bragg gratings with novel waveguide models fabricated in bulk glass via fs-laser writing and their slow-light effects - 6768916.pdf
Creators: name: Chen, Qingtao
name: Boisvert, Jean-Sébastien
name: SHARAWI, Mohammad
name: Kashyap, Raman
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Schematic of setup for measurments, some supporting results, calculations and so on
ИНТЕРВЬЮ С АЛЕКСАНДРОЙ ДВОРНИКОВОЙ
Creators: name: Дворникова Александра
Publisher: name: Экопоэзис: экогуманитарные теория и практика
Year: 2021
Subjects: ИСКУССТВО
КРАСОТА
ЛЕС
ПРИРОДА
ТВОРЧЕСТВО

description: Художница из Санкт-Петербурга, Александра Дворникова, дала интервью нашему журналу, рассказав о своем творчестве и его связи с природой, о роли художника в продвижении экологических ценностей и экологической культуры, формировании экологического сознания, об общении с миром природы как источнике вдохновения, красоты и исцеления.
A bound on the scrambling index of a primitive matrix using Boolean rank
Creators: name: Akelbek, Mahmud
name: Fital, Sandra
name: Shen, Jian
Publisher: name: arXiv
Year: 2009
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 15A48; 05C20; 05C50; 05C75

description: The scrambling index of an $n\times n$ primitive matrix $A$ is the smallest positive integer $k$ such that $A^k(A^{t})^k=J$, where $A^t$ denotes the transpose of $A$ and $J$ denotes the $n\times n$ all ones matrix. For an $m\times n$ Boolean matrix $M$, its {\it Boolean rank} $b(M)$ is the smallest positive integer $b$ such that $M=AB$ for some $m \times b$ Boolean matrix $A$ and $b\times n$ Boolean matrix $B$. In this paper, we give an upper bound on the scrambling index of an $n\times n$ primitive matrix $M$ in terms of its Boolean rank $b(M)$. Furthermore we characterize all primitive matrices that achieve the upper bound.
description: 13 pages, 3 tables
Archaeology at Letchworth Museum: telling stories about the past
Creators: name: Fitzpatrick-Matthews, Keith
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Quantum group connections
Creators: name: Lewandowski, Jerzy
name: Okolow, Andrzej
Publisher: name: arXiv
Year: 2008
Subjects: subject: Mathematical Physics (math-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The Ahtekar-Isham C*-algebra known from Loop Quantum Gravity is the algebra of continuous functions on the space of (generalized) connections with a compact structure Lie group. The algebra can be constructed by some inductive techniques from the C*-algebra of continuous functions on the group and a family of graphs embedded in the manifold underlying the connections. We generalize the latter construction replacing the commutative C*-algebra of continuous functions on the group by a non-commutative C*-algebra defining a compact quantum group.
description: 40 pages, LaTeX2e, minor mistakes corrected, abstract slightly changed
Iron Age Slag - No Puns Please!
Creators: name: McLaren, Dawn
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Dirac-Kahler Theory and Massless Fields
Creators: name: Pletyukhov, V. A.
name: Strazhev, V. I.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Three massless limits of the Dirac-Kahler theory are considered. It is shown that the Dirac-Kahler equation for massive particles can be represented as a result of the gauge-invariant mixture (topological interaction) of the above massless fields.
description: 10 pages, to appear in Proceedings of International conference in honor of Ya. B. Zeldovich 95th Anniversary, April 20-23, 2009, Minsk, Belarus
Additional file 1 of Identifying the critical states and dynamic network biomarkers of cancers based on network entropy
Creators: name: Liu, Juntan
name: Ding, Dandan
name: Zhong, Jiayuan
name: Liu, Rui
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Additional file 1. Supplementary information of LNE.
The asymptotic distribution and Berry--Esseen bound of a new test for independence in high dimension with an application to stochastic optimization
Creators: name: Liu, Wei-Dong
name: Lin, Zhengyan
name: Shao, Qi-Man
Publisher: name: arXiv
Year: 2009
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60F05 (Primary) 62F05 (Secondary)

description: Let $\mathbf{X}_1,...,\mathbf{X}_n$ be a random sample from a $p$-dimensional population distribution. Assume that $c_1n^α\leq p\leq c_2n^α$ for some positive constants $c_1,c_2$ and $α$. In this paper we introduce a new statistic for testing independence of the $p$-variates of the population and prove that the limiting distribution is the extreme distribution of type I with a rate of convergence $O((\log n)^{5/2}/\sqrt{n})$. This is much faster than $O(1/\log n)$, a typical convergence rate for this type of extreme distribution. A simulation study and application to stochastic optimization are discussed.
description: Published in at http://dx.doi.org/10.1214/08-AAP527 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Sarah Matthews: Senior Processor Top to Toe in Mud
Creators: name: White, Steve
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Sacrilege in Marlborough
Creators: name: Pitts, Mike
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
KADINLARIN GEBELİĞİ SONLANDIRMA HAKKINDAKİ BİLGİ DÜZEYLERİNİN ÖLÇÜLMESİ
Creators: name: Şeyma Sancak, Merve
Publisher: name: Zenodo
Year: 2019
Subjects: Gebeliği sonlandırılması,kürtaj,anne,baba,cinayet...

description: Ülkemizdeki kadınların gebeliği sonlandırma hakkındaki bilgi düzeylerinin ölçülmesi amaçlanmıştır.
ИНТЕРПРЕТАЦИЯ ПРИРОДНОГО: СОВРЕМЕННЫЕ ВЗГЛЯДЫ НА СКАЛЫ УЧЕНЫХ
Creators: name: Додсон Донна
Publisher: name: Экопоэзис: экогуманитарные теория и практика
Year: 2021
Subjects: ГУНШИ
СКАЛЫ УЧЕНЫХ
СУСОК
СУЙСЕКИ
СКАЛА ТАЙХУ

description: В статье рассматривается феномен «скал ученых», представленный в искусстве Восточной Азии и выступивший в качестве основы кураторского проекта автора при организации выставки, проведенной 21 октября - 30 ноября 2020 г. на базе Корейского культурного центра в Нью-Йорке. Данная выставка обсуждается с точки зрения традиционной эстетики Стран Востока. Обсуждаются характерные для разных культурных традиций связи между искусством и природой. Из-за ограничений, вызванных пандемией COVID-19, автор статьи разработала серию онлайн-мероприятий, чтобы обсудить основные темы выставки с художниками и кураторами музеев, историками искусства и частными коллекционерами.
ИСКУССТВО НЕЖНОСТИ: ВОПЛОЩЕННАЯ МУДРОСТЬ В ЭКОЛОГИЧЕСКОЙ АРТ-ТЕРАПИИ
Creators: name: Э’Коурт Беверли
Publisher: name: Экопоэзис: экогуманитарные теория и практика
Year: 2021
Subjects: АРТ-ТЕРАПИЯ
ВНИМАНИЕ
НЕЖНОСТЬ
ОСОЗНАННОСТЬ
ПОЭЗИЯ
ПРИРОДА
ТИШИНА
ЭКОЛОГИЯ

description: Данная статья подготовлена на основе доклада Беверли Э’Коурт, представленного на первой международной научно-практической онлайн конференции «Экологическая/природоцентрированная арт-терапия: международные и мультикультурные перспективы». В статье раскрывается свойство нежности как обращенное к разным формам жизни и реализуемое не только в отношениях между людьми, но и их отношениях с миром природы. Арт-терапия при этом выступает в качестве средства развития этого драгоценного качества в повседневной жизни и вносит свой вклад в восстановление гармоничных отношений с природой.
Development of stabilizing shoe inserts and testing apparatus to mitigate ankle injury in sports
Creators: name: Grothen, Evan
name: Dowd, Teal
name: Hansen, Colin
name: Mansson, Jan-Anders
Publisher: name: Loughborough University
Year: 2024

description: Engineering of Sport 15 - Proceedings from the 15th International Conference on the Engineering of Sport (ISEA 2024)
The ongoing effort to protect athletes in jumping sports centers around the ability to protect the ankle from injury. Ankle injuries are the most frequent injury to basketball and volleyball players, accounting for 58% and 63 % of all injuries respectively. From earlier NCAA studies, it was reported that 77.1 % of ankle sprain injuries are to the lateral ligament complex, which indicates a low ankle sprain. Multiple ankle sprain prevention methods already exist to resist the ankle sprain mechanism such as ankle braces. The weakest and primarily injured ligament of this complex is the anterior talofibular ligament (ATFL). An ankle sprain is induced by the rapid supination of the foot, with a 60-degree angle of supination being sufficient to injure the ATFL and the major component in injuring the ankle. Also, applying a stiff counterforce to the ankle will redirect the force induced to the leg in an ankle sprain up to the knee or hip, resulting in a more serious injury. Therefore, footwear that provides strength with force absorption to the ATFL and disallows a 60- degree angle of supination is ideal in preventing injury to the ATFL. This paper will discuss the fabrication of a tailored prototype that resists ankle supination and a method for prototype validation.
Contradiction of expectations based on specific and diffuse information
Creators: name: Frances, M. Reimer
Publisher: name: University of British Columbia
Year: 2011

description: Previous research concerned with self-other expectations has suggested that an individual's expectations can be based on two types of information. In a task-oriented group, information about prior performance behavior can lead to self-other expectations as can information regarding status differences. Within the conditions of the theory, these information types are defined as specific and diffuse characteristics respectively. It has been demonstrated that when an individual's expectations are contradicted there is a tendency for him to resist changing his expectations. In this paper it is proposed that expectations based on diffuse characteristics are more resistant to change than expectations based on specific characteristics. An experiment is conducted to examine what happens when each expectation type is contradicted. The results are not supportive, they indicate that expectations based on specific characteristics take longer to change than expectations based on diffuse characteristics. Suggestions are then made for a redevelopment of the theoretical structure.
Ontologies and Cuneiform
Creators: name: , Terhi
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Phamacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: pharmacometabolomics
pharmacometabonomics
metabolomics
breast
cancer

description: Defining biomarkers that predict therapeutic effects and adverse events is a crucial mandate to guide patient selection for personalized cancer treatments. In the present study, we applied a pharmacometabolomics approach to identify biomarkers potentially associated with pathological complete response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer patients. Based on histological response the 34 patients enrolled in the study were subdivided into two groups: good responders (n = 15) and poor responders (n = 19). The pre-treatment serum targeted metabolomics profile of all patients were analyzed by liquid chromatography tandem mass spectrometry and the differences in the metabolomics profile between the two groups was investigated by multivariate partial least squares discrimination analysis. The most relevant metabolites that differentiate the two groups of patients were spermidine and tryptophan. The Good responders showed higher levels of spermidine and lower amounts of tryptophan compared with the poor responders (p < 0.001, q < 0.05). The serum level of these two metabolites identified patients who achieved a pathological complete response with a sensitivity of 90% [0.79-1.00] and a specificity of 0.87% [0.67-1.00]. These preliminary results support the role played by the individual patients' metabolism in determining the response to cancer treatments and may be a useful tool to select patients that are more likely to benefit from the trastuzumab-paclitaxel treatment.
ИСПОЛЬЗОВАНИЕ ТЕХНИК ЭКОЛОГИЧЕСКОЙ АРТ-ТЕРАПИИ В ПРОЦЕССЕ РЕАБИЛИТАЦИИ УПОТРЕБЛЯЮЩИХ ПСИХОАКТИВНЫЕ ВЕЩЕСТВА
Creators: name: Богачёв Олег Владимирович
Publisher: name: Экопоэзис: экогуманитарные теория и практика
Year: 2021
Subjects: АРТ-ТЕРАПИЯ
КЛИНИЧЕСКАЯ СИСТЕМНАЯ АРТ-ТЕРАПИЯ
РЕАБИЛИТАЦИЯ
ПСИХОАКТИВНЫЕ ВЕЩЕСТВА
ЭКОЛОГИЧЕСКИЙ ПОДХОД

description: Приводятся обоснование и некоторые результаты использования экологического подхода в арт-терапии в процессе реабилитации употребляющих психоактивные вещества. Техники экологической арт-терапии проиллюстрированы примерами из практической работы, связанной с проведением занятий на базе дневного стационара и амбулаторного культурно-оздоровительного клуба. Эффекты, проявившиеся в процессе создания арт-объектов и инсталляций из природных материалов и фотосъемки среды, свидетельствуют о разностороннем воздействии данных видов работы на личность и состояние реабилитируемых. Был показан значительный потенциал экологического подхода для гармонизации нарушенных отношений личности (с собой, природой, другими людьми, обществом и др.) на основе взаимодействия со средой.
Molecular phylogeny and taxonomy of the Epictia goudotii species complex (serpentes: Leptotyphlopidae: Epictinae) in Middle America and northern South America
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: Epictia albifrons
Epictia tenella
Middle America
Epictia goudotii Species complex
Northern South America
Threadsnakes
Molecular phylogeny

description: © 2016 McCranie and Hedges. Here we review the systematics of the threadsnakes of the Epictia goudotii Species complex in Middle and northern South America using external morphology and molecular data. Two species, Epictia goudotii and E. magnamaculata, are currently recognized from that region, but we provide evidence for recognizing, as species, three other nominal forms usually treated as subspecies of E. goudotii: E. ater, E. bakewelli, and E. phenops. Thus, together with E. columbi (Bahamas), we recognize six species in the Epictia goudotii Species complex. Because E. albifrons from northern South America has been confused with E. goudotii in the past, we also briefly discuss the taxonomic status of that species and its apparent close relative E. tenella, which are not members of the E. goudotii complex.
SecSip: A Stateful Firewall for SIP-based Networks
Creators: name: Lahmadi, Abdelkader
name: Festor, Olivier
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cryptography and Security (cs.CR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: SIP-based networks are becoming the de-facto standard for voice, video and instant messaging services. Being exposed to many threats while playing an major role in the operation of essential services, the need for dedicated security management approaches is rapidly increasing. In this paper we present an original security management approach based on a specific vulnerability aware SIP stateful firewall. Through known attack descriptions, we illustrate the power of the configuration language of the firewall which uses the capability to specify stateful objects that track data from multiple SIP elements within their lifetime. We demonstrate through measurements on a real implementation of the firewall its efficiency and performance.
Additional file 1 of A closed-loop ventilation mode that targets the lowest work and force of breathing reduces the transpulmonary driving pressure in patients with moderate-to-severe ARDS
Creators: name: Buiteman-Kruizinga, Laura A.
name: van Meenen, David M. P.
name: Bos, Lieuwe D. J.
name: van der Heiden, Pim L. J.
name: Paulus, Frederique
name: Schultz, Marcus J.
Publisher: name: figshare
Year: 2023
Subjects: Biophysics
Space Science
Medicine
Biotechnology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Science Policy

description: Additional file 1: Table S1. List of significant pairwise comparisons per time point, significance was determined at a P value < 0.003. Table S2. Specification of the generalized linear mixed model analysis. Figure S1. Line plots showing the mean changes and individual changes over time of transpulmonary ΔP, VT and RR during the two study blocks of the two ventilation modes in the study. Figure S2. CRS vs. VT between closed-loop ventilation and conventional ventilation, and transpulmonary ΔP vs. VT between closed-loop ventilation and conventional ventilation. A negative value means that the parameter decreased with closed-loop ventilation, and a higher value means that the parameter increased with closed-loop ventilation. All dots represent the mean value of an individual patient. Figure S3. Scatterplots of CRS vs. VT and transpulmonary ΔP vs. VT with closed-loop ventilation and conventional ventilation. Each dot was characterized by a single data point. Figure S4. Showing individual patient data of the effect of the change of the ventilation mode on PEEP setting. Figure S5. Showing transpulmonary ΔP per patient during every time point, with closed-loop ventilation and conventional ventilation. The head with number represents the corresponding patient, the x-axis represent the 16 time points per block. Figure S6. Showing PEEP per patient during every time point, with closed-loop ventilation and conventional ventilation. The head with number represents the corresponding patient, the x-axis represent the 16 time points per block. Figure S7. Showing the tidal volumeper patient during every time point, with closed-loop ventilation and conventional ventilation. The head with number represents the corresponding patient, the x-axis represent the 16 time points per block. Figure S8. Showing the respiratory rateper patient during every time point, with closed-loop ventilation and conventional ventilation. The head with number represents the corresponding patient, the x-axis represent the 16 time points per block. Figure S9. Violin plot of pairwise comparisons at individual time points of ΔP. Figure S10. Violin plot of pairwise comparisons at individual time points of transpulmonary ΔP. Figure S11. Violin plot of pairwise comparisons at individual time points of RR. Figure S12. Violin plot of pairwise comparisons at individual time points of MP. Figure S13. Violin plot of pairwise comparisons at individual time points of transpulmonary MP.
Metabolic determinants and anthropometric indicators impact clinical-pathological features in epithelial ovarian cancer patients
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: epithelial ovarian cancer
fasting glucose
body mass index
FIGO stage
tumour grade

description: © Ivyspring International Publisher. Background: Over the last twenty years, the efforts of the scientific community devoted to the comprehension and treatment of ovarian cancer have remained poorly remunerative, with the case-fatality ratio of this disease remaining disappointedly high. Limited knowledge of the basic principles regulating ovarian carcinogenesis and factors impacting the course of disease may significantly impair our ability to intervene in early stages and lessen our expectations in terms of treatment outcomes. In the present study, we sought to assess whether metabolic factors and anthropometric indicators, i.e., pre-treatment fasting glucose and body mass index, are associated with renown cancer related prognostic factors such as tumour stage and grade at diagnosis. Materials and Methods: Study participants were 147 women diagnosed with epithelial ovarian cancer and treated with platinum based regimens and/or surgery at the Regina Elena National Cancer Institute of Rome, Italy. Glucose levels were assessed at the institutional laboratories on venous blood collected in overnight fasting conditions and prior to any therapeutic procedure. Stage was coded according to the FIGO staging system based on the results of the diagnostic workup, while tumour grade was locally assessed by an expert pathologist. Participants' characteristics were descriptively analyzed for the overall study population and in a subgroup of 70 patients for whom data on body mass index (BMI) were available. FIGO stage and grade were compared by categories of pre-treatment fasting glucose defined upon the median value, i.e., 89 mg/dl. The association of interest was tested in regression models including BMI. Results: For the overall study population, patients in the lowest category of fasting glucose were significantly more likely to exhibit a FIGO stage III-IV at diagnosis compared with their counterpart in the highest glucose category (81.3 vs 66.7%, p: 0.021). Subgroup analysis in 70 patients with BMI data confirmed this association (81.5 vs 55.8, p: 0.049), which remained significant when tested in regression models including BMI (OR: 0.28 95% CI 0.086-0.89, p: 0.031). No relevant evidence emerged when testing the association between fasting glucose and tumour grade. Conclusions: In patients diagnosed with epithelial ovarian cancer, pre-treatment glucose levels appear to be inversely associated with FIGO stage. Further studies are warranted to eventually confirm and correctly interpret the implications of this novel finding.
Tim Braybrooke: Senior Archaeologist Daydreams of Experimental Archaeology & BBQs
Creators: name: White, Steve
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Integrating TRPV1 Receptor Function with Capsaicin Psychophysics
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: subject: 1115 Pharmacology and Pharmaceutical Sciences
subject: Biomedical
subject: Basic Science
subject: Pain Research
subject: Nutrition
subject: Dental/Oral and Craniofacial Disease
subject: Clinical Research
subject: Neurosciences
subject: FOS: Clinical medicine
subject: 2.1 Biological and endogenous factors
subject: 1.1 Normal biological development and functioning

description: © 2016 Gregory Smutzer and Roni K. Devassy. Capsaicin is a naturally occurring vanilloid that causes a hot, pungent sensation in the human oral cavity. This trigeminal stimulus activates TRPV1 receptors and stimulates an influx of cations into sensory cells. TRPV1 receptors function as homotetramers that also respond to heat, proinflammatory substances, lipoxygenase products, resiniferatoxin, endocannabinoids, protons, and peptide toxins. Kinase-mediated phosphorylation of TRPV1 leads to increased sensitivity to both chemical and thermal stimuli. In contrast, desensitization occurs via a calcium-dependent mechanism that results in receptor dephosphorylation. Human psychophysical studies have shown that capsaicin is detected at nanomole amounts and causes desensitization in the oral cavity. Psychophysical studies further indicate that desensitization can be temporarily reversed in the oral cavity if stimulation with capsaicin is resumed at short interstimulus intervals. Pretreatment of lingual epithelium with capsaicin modulates the perception of several primary taste qualities. Also, sweet taste stimuli may decrease the intensity of capsaicin perception in the oral cavity. In addition, capsaicin perception and hedonic responses may be modified by diet. Psychophysical studies with capsaicin are consistent with recent findings that have identified TRPV1 channel modulation by phosphorylation and interactions with membrane inositol phospholipids. Future studies will further clarify the importance of capsaicin and its receptor in human health and nutrition.
HUR protects NONO from degradation by mir 320 which is induced by p53 upon UV irradiation
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: DNA damage response
NONO
p53
HUR
mir320a

description: UV radiations challenge genomic stability and are a recognized cancer risk factor. We previously found that the RNA-binding protein NONO regulates the intra-S phase checkpoint and its silencing impaired HeLa and melanoma cell response to UV-induced DNA damage. Here we investigated the mechanisms underlying NONO regulation upon UVC treatment. We found that UVC rays induce the expression of mir320a, which can indeed target NONO. However, despite mir320a induction, NONO mRNA and protein expression are not affected by UVC. We found through RNA immunoprecipitation that UVC rays induce the ubiquitous RNA-binding protein HUR to bind NONO 5'UTR in a site overlapping mir320a binding site. Both HUR silencing and its pharmacological inhibition induced NONO downregulation following UVC exposure, whereas concomitant mir320a silencing restored NONO stability. UVC-mediated mir320a upregulation is triggered by p53 binding to its promoter, which lies within a region marked by H3K4me3 and H3K27ac signals upon UVC treatment. Silencing mir320a sensitizes cells to DNA damage. Overall our findings reveal a new mechanism whereby HUR protects NONO from mir320-mediated degradation upon UVC exposure and identify a new component within the complex network of players underlying the DNA damage response adding mir320a to the list of p53-regulated targets upon genotoxic stress.
Globalisation
Creators: name: Pagi, Hembo
Publisher: name: Archaeology Data Service
Year: 2012

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2016
Subjects: subject: 1112 Oncology and Carcinogenesis
subject: Biomedical
subject: Basic Science
subject: Cancer
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Stem Cell Research
subject: Brain Cancer
subject: Rare Diseases
subject: Brain Disorders
subject: Orphan Drug
subject: 2.1 Biological and endogenous factors

description: © 2016 Alessia Fidoamore et al. Among all solid tumors, the high-grade glioma appears to be the most vascularized one. In fact, "microvascular hyperplasia" is a hallmark of GBM. An altered vascular network determines irregular blood flow, so that tumor cells spread rapidly beyond the diffusion distance of oxygen in the tissue, with the consequent formation of hypoxic or anoxic areas, where the bulk of glioblastoma stem cells (GSCs) reside. The response to this event is the induction of angiogenesis, a process mediated by hypoxia inducible factors. However, this new capillary network is not efficient in maintaining a proper oxygen supply to the tumor mass, thereby causing an oxygen gradient within the neoplastic zone. This microenvironment helps GSCs to remain in a "quiescent" state preserving their potential to proliferate and differentiate, thus protecting them by the effects of chemo-and radiotherapy. Recent evidences suggest that responses of glioblastoma to standard therapies are determined by the microenvironment of the niche, where the GSCs reside, allowing a variety of mechanisms that contribute to the chemo-and radioresistance, by preserving GSCs. It is, therefore, crucial to investigate the components/factors of the niche in order to formulate new adjuvant therapies rendering more efficiently the gold standard therapies for this neoplasm.