cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Differential gene expression in primary fibroblasts induced by proton and cobalt-60 beam irradiation
Creators: name: Nielsen, Steffen
name: Bassler, Niels
name: Grzanka, Leszek
name: Swakon, Jan
name: Olko, Pawel
name: Andreassen, Christian Nicolaj
name: Overgaard, Jens
name: Alsner, Jan
name: Sørensen, Brita Singers
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Introduction: Proton beam therapy delivers a more conformal dose distribution than conventional radiotherapy, thus improving normal tissue sparring. Increasing linear energy transfer (LET) along the proton track increases the relative biological effectiveness (RBE) near the distal edge of the Spread-out Bragg peak (SOBP). The severity of normal tissue side effects following photon beam radiotherapy vary considerably between patients. Aim: The dual study aim was to identify gene expression patterns specific to radiation type and proton beam position, and to assess whether individual radiation sensitivity influences gene expression levels in fibroblast cultures irradiated in vitro. Methods: The study includes 30 primary fibroblast cell cultures from patients previously classified as either radiosensitive or radioresistant. Cells were irradiated at three different positions in the proton beam profile: entrance, mid-SOBP and at the SOBP distal edge. Dose was delivered in three fractions × 3.5 Gy(RBE) (RBE 1.1). Cobalt-60 (Co-60) irradiation was used as reference. Real-time qPCR was performed to determine gene expression levels for 17 genes associated with inflammation response, fibrosis and angiogenesis. Results: Differences in median gene expression levels were observed for multiple genes such as IL6, IL8 and CXCL12. Median IL6 expression was 30%, 24% and 47% lower in entrance, mid-SOBP and SOBP distal edge groups than in Co-60 irradiated cells. No genes were found to be oppositely regulated by different radiation qualities. Radiosensitive patient samples had the strongest regulation of gene expression; irrespective of radiation type. Conclusions: Our findings indicate that the increased LET at the SOBP distal edge position did not generally lead to increased transcriptive response in primary fibroblast cultures. Inflammatory factors were generally less extensively upregulated by proton irradiation compared with Co-60 photon irradiation. These effects may possibly influence the development of normal tissue damage in patients treated with proton beam therapy.
Re-examination of the Etiology of Fatal Undifferentiated Fever/Bovine Resipratory Disease
Creators: name: Booker, C. W.
name: Guichon, P. T.
name: Jim, G. K.
name: Schunicht, O. C.
name: Wildman, B. K.
name: Pittman, T. J.
name: Perrett, T.
name: Morley, P. S.
name: Jones, C. W.
name: Pollock, C. M.
name: Janzen, E. D.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Results of this study demonstrate that several etiologic agents and pathologic processes are involved in fatal BRD of feedlot cattle, with MH (peracute, acute, and subacute cases) and MB (subacute, bronchiolar, and chronic cases) identified as the predominant pathogens in the vast majority of fatal BRD cases.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Influence of Using Fan and Sprinkler Cooling Systeins on Physiological Responses of Heat-Stressed Holstein Cows
Creators: name: Baei, S. F. Rezazadeh
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Lactating dairy cattle produce large amounts of heat due to digestion and metabolic processes; this heat must be exchanged with the environment to maintain normal body temperature. The Temperature Humidity Index (THI) could be used to evaluate thermal stress caused by the environment. This index combines relative humidity (RH) and ambient temperature (Ta) into a single value to estimate the potential environmental heat load. An environment is generally considered stressful for cattle when the THI exceeds 72. Sprinkling and supplemental airflow -to-reduce heat stress (HS) has been evaluated in many studies. Thirty Holstein dairy cows were used in this study to evaluate the effect of three different cooling systems on physiological responses, including rectal temperature (RT), respiration (RR) and heart rate (HR), during August and September, with daily average Ta between 73 and 86°F (23 and 30°C) and Rh between 67 and 91 % at Sari City, Northern Iran. Control cows had access to six fans (C). A second group was cooled with twelve fans (F), and the third group of cows was cooled with twelve fans and sprinklers (F/S). The maximum THI during the trial ranged from 73.1 to 99.7 (83.63 ± 3.333). Ta, and as a result THI, were less (P<0.05) in F/S (77.8 ± 6.58°F and 74.9 ± 5.62) and F (82.4 ± 7.44°F and 78.8 ± 6.44) groups compared to the C group (83. 7 ± 7. 71 °F and 79.9 ± 6.64). The average of RT (103.1 ± l.02°F; 39.5 ± 0.566°C), RR (79.2 ± 10.2 breaths/min) and HR (79.4 ± 4.32 beats/ min) of cows in the C group were higher (P < 0.05) than those in the F (102.6 ± 0.96°F [39.2 ± 0.638°C], 67.7 ± 12.8 and 77.3 ± 3.98) and S/F (101.7 ± 0.94°F [38.7 ± 0.521°C], 55.1 ± 12.7 and 76.7 ± 4.60) groups, respectively. These results indicate that a cooling system based on spray and fans is an effective alternative to alleviate the negative effects of HS on physiological responses in lactating Holstein cows under warm and humid conditions.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Christopher Landau: A Theology of Disagreement
Creators: name: Sandnes, Karl Olav
Publisher: name: Tidsskrift for Praktisk Teologi
Year: 2022

description: A Theology of Disagreement: New Testament Ethics for Ecclesial Conflicts
description: Tidsskrift for Praktisk Teologi, Vol 39 Nr 1 (2022): Tidsskrift for praktisk teologi
Serum Neutralizing Antibody to the Alpha Toxin of Clostridium perfringens type A in Dairy Calves Fed Colostrum from Immunized Dams
Creators: name: Van Metre, David C.
name: Morley, Paul S.
name: Walz, Michelle L.
name: Dobberstein, Skye E.
name: Nichols, Jeruesha A. R.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: The goal of this study was to determine if immunization of pregnant dairy cows and heifers with a commercially available vaccine affected the serum neutralizing antibody titer to alpha toxin (AbAT) in their colostrum-fed calves.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Evaluation of Castration Technique, Pain Manageinent, and Castration Tiining in Young Feedlot Bulls in Alberta
Creators: name: Wildman, B. K.
name: Pollock, C. M.
name: Schunicht, O. C.
name: Booker, C. W.
name: Guichon, P. T.
name: Jim, G. K.
name: Pittman, T. J.
name: Perrett, T.
name: Morley, P. S.
name: Jones, C. W.
name: Lee, S. R.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: A randomized commercial feedlot study was conducted to evaluate the effect of castration technique (band castration (BC) versus surgical castration (SC)), pain management (anesthesia/analgesia (AA) versus no anesthesia/analgesia (NA)), and castration timing (allocation (DO) versus 70 days post-allocation (D70)) on animal health, feedlot performance, and carcass characteristic variables of young bulls. There were 960 bulls and 48 pens used in a complete block design, with no commingling of animals from different experimental groups in the same pens. In the preliminary feedlot performance data summary from allocation to D159, ADG ( +0.051 lb./day, P=0.188) and DM:G (-0.117, P=0.060) were improved in pens castrated at DO versus pens castrated at D70; ADG ( +0.076 lb./day, P=0.049) and DM:G (-0.069, P=0.264) were improved in pens castrated using BQ versus pens castrated using SC; and ADG ( +0.025 lb/day, P=0.511) and DM:G (-0.079, P=0.204) were improved in pens castrated with NA versus those castrated with AA. There were no significant interactions detected between castration timing, castration technique, and pain management strategies. There were minimal differences in mortality from DO to D159 between the pens in each of the castration options (DO versus D70; BC versus SC; or AA versus NA). The preliminary data from DO to D159 are interesting; however, final data from allocation through slaughter are necessary to complete the overall assessment of each castration option. Understanding the relative cost-effectiveness of each castration option will help bridge the gap that currently exists in determining optimal castration management in commercial feedlot settings.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
title: Nachweis von zirkulierenden Urothelkarzinomzellen in Blutproben mittels verschiedenen größenbasierten Anreicherungssystemen
Creators: name: Verst, L.-M.
name: Humberg, V.
name: Schlack, K.
name: Bögemann, M.
name: Schrader, A. J.
name: Bernemann, C.
name: Krabbe, L.-M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Liquid Biopsy, d.h. die Blutentnahme mit dem Ziel, Aussagen über die Krebserkrankung eines Patienten zu treffen, hat in den letzten Jahren große Fortschritte erzielt. So ist das EpCAM-basierte Cellsearch®-System als Detektionssystem für zirkulierende Tumorzellen (CTCs)[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 66. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie
title: Onkologisches Outcome, Lebensqualität und psychosoziale Belastung nach radikaler Zystektomie (RC) wegen Urothelkarzinoms der Harnblase – Versorgungsforschung anhand der Daten aus der fachurologischen Anschlussrehabilitation (AHB)
Creators: name: Müller, Guido
name: Butea-Bocu, Marius
name: Bahlburg, Henning
name: Otto, Ullrich
name: Noldus, Joachim
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Vor dem Hintergrund der Zunahme von fast-track-Konzepten und neoadjuvanter Chemotherapie soll das aktuelle Outcome der Patienten nach RC dargestellt werden. Methode: 532 Patienten nach RC und Anlage einer Harnableitung (Conduit/Neoblase), die zwischen 4/2018 und 3/2019[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 66. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie
Drop-in-dåp gir tilgang på mere kunnskap om dåp
Creators: name: Ellinggard, Stein
Publisher: name: Tidsskrift for Praktisk Teologi
Year: 2022

description: The article presents results from a study of drop-in baptisms in Norway. The study is based on interviews with parents who have chosen to baptise their children by drop- in baptism and with adults who have been baptised. They were baptised in different congregations in the Church of Norway from 2015 to 2019. The article tries to answer two questions: what were their reasons for being baptised, and why did they choose drop-in baptism? The study shows that the baptism functions as an initiation ritual into different communities, which gave a feeling of belonging and identity. It also shows that authenticity is important for people to explain their reason for baptism, and that drop-in baptism fits well into the life of the modern person. The study uncovers the diversity and complexity of the religiosity and shows the different motives humans have for choosing drop-in baptism. This study will contribute to a better understanding of what people are thinking about baptism and to the discussion about further practices in the church.
description: Tidsskrift for Praktisk Teologi, Vol 39 Nr 1 (2022): Tidsskrift for praktisk teologi
Spatial rectal dose/volume metrics predict patient-reported gastro-intestinal symptoms after radiotherapy for prostate cancer
Creators: name: Casares-Magaz, Oscar
name: Muren, Ludvig Paul
name: Moiseenko, Vitali
name: Petersen, Stine E.
name: Pettersson, Niclas Johan
name: Høyer, Morten
name: Deasy, Joseph O.
name: Thor, Maria
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 60506 Virology

description: Background: Gastro-intestinal (GI) toxicity after radiotherapy (RT) for prostate cancer reduces patient’s quality of life. In this study, we explored associations between spatial rectal dose/volume metrics and patient-reported GI symptoms after RT for localized prostate cancer, and compared these with those of dose–surface/volume histogram (DSH/DVH) metrics. Material and methods: Dose distributions and six GI symptoms (defecation urgency/emptying difficulties/fecal leakage, ≥Grade 2, median follow-up: 3.6 y) were extracted for 200 patients treated with image-guided RT in 2005–2007. Three hundred and nine metrics assessed from 2D rectal dose maps or DSHs/DVHs were subject to 50-times iterated five-fold cross-validated univariate and multivariate logistic regression analysis (UVA, MVA). Performance of the most frequently selected MVA models was evaluated by the area under the receiving–operating characteristics curve (AUC). Results: The AUC increased for dose-map compared to DSH/DVH-based models (mean SD: 0.64 ± 0.03 vs. 0.61 ± 0.01), and significant relations were found for six versus four symptoms. Defecation urgency and faecal leakage were explained by high doses at the central/upper and central areas, respectively; while emptying difficulties were explained by longitudinal extensions of intermediate doses. Conclusions: Predictability of patient-reported GI toxicity increased using spatial metrics compared to DSH/DVH metrics. Novel associations were particularly identified for emptying difficulties using both approaches in which intermediate doses were emphasized.
Spatial rectal dose/volume metrics predict patient-reported gastro-intestinal symptoms after radiotherapy for prostate cancer
Creators: name: Casares-Magaz, Oscar
name: Muren, Ludvig Paul
name: Moiseenko, Vitali
name: Petersen, Stine E.
name: Pettersson, Niclas Johan
name: Høyer, Morten
name: Deasy, Joseph O.
name: Thor, Maria
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 60506 Virology

description: Background: Gastro-intestinal (GI) toxicity after radiotherapy (RT) for prostate cancer reduces patient’s quality of life. In this study, we explored associations between spatial rectal dose/volume metrics and patient-reported GI symptoms after RT for localized prostate cancer, and compared these with those of dose–surface/volume histogram (DSH/DVH) metrics. Material and methods: Dose distributions and six GI symptoms (defecation urgency/emptying difficulties/fecal leakage, ≥Grade 2, median follow-up: 3.6 y) were extracted for 200 patients treated with image-guided RT in 2005–2007. Three hundred and nine metrics assessed from 2D rectal dose maps or DSHs/DVHs were subject to 50-times iterated five-fold cross-validated univariate and multivariate logistic regression analysis (UVA, MVA). Performance of the most frequently selected MVA models was evaluated by the area under the receiving–operating characteristics curve (AUC). Results: The AUC increased for dose-map compared to DSH/DVH-based models (mean SD: 0.64 ± 0.03 vs. 0.61 ± 0.01), and significant relations were found for six versus four symptoms. Defecation urgency and faecal leakage were explained by high doses at the central/upper and central areas, respectively; while emptying difficulties were explained by longitudinal extensions of intermediate doses. Conclusions: Predictability of patient-reported GI toxicity increased using spatial metrics compared to DSH/DVH metrics. Novel associations were particularly identified for emptying difficulties using both approaches in which intermediate doses were emphasized.
Open Pharma: status update Jan-Mar 2022
Creators: name: Ounsworth, Francesca
name: Edgell, Caitlin
name: Rosenberg, Adeline
Publisher: name: Open Pharma
Year: 2022
Subjects: Science, technology and engineering curriculum and pedagogy
Health care administration
Pharmacology and pharmaceutical sciences not elsewhere classified

description: We’ve had a great start to the year, with lots of new research taking place and a strong Open Pharma presence at several meetings and conferences.
title: Das im Rahmen der radikalen Zystektomie entdeckte, inzidentelle Prostatakarzinom (IPCa) zeigt ein unterschiedliches miRNA Expressionsprofil im Vergleich zum bioptisch gesicherten PCa
Creators: name: Richter, Konstantin
name: von Brandenstein, Melanie
name: Köditz, Barbara
name: Fries, Jochen
name: Heidenreich, Axel
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Diagnose eines Prostatakarzinoms während einer radikalen Zytstektomie in Falle eines Harnblasenkarzinoms liegt bei 30–40%. Es besteht eine kontroverse Diskussion, ob ein IPCa das gleiche molekulare Profil hinsichtlich der Metastasierungstendenz aufweist wie Tumore, die[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 66. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie
title: Fallstricke der MRT-Fusionsbiopsie – Ein Case Report
Creators: name: Winter, Nicola
name: Machtens, Stefan
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die MRT-fusionierte Prostatabiopsie auf Basis eines multiparametrischen MRTs entwickelt sich zunehmend zu einem Standardverfahren in der Diagnostik des Prostatakarzinoms. In der aktuellen S3-Leitlinie ist sie für alle Re-Biopsien empfohlen. Dennoch handelt es sich noch um ein relativ[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 66. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie
Measure Process Maturity for Quality Management Systems
Creators: name: Bürgy, Pascal
Publisher: name: Hochschule für Wirtschaft FHNW
Year: 2015
Subjects: subject: Process
subject: Maturity Measurement
subject: Quality Management
subject: ISO 9001:2015
subject: COBIT 5 PAM
subject: Small and Mid-Sized Enterprises (SME)
subject: Swiss based
subject: Glaux Soft AG
subject: Master Thesis
subject: Design Science Research
subject: 004 - Computer Wissenschaften, Internet

description: ISO 9001:2015 is a widespread standard for quality management – also and espe-cially within the IT industry. As with every standard or best practice, quality manage-ment systems require a continuous improvement whose characteristics are defined on a high-level basis within ISO 9001:2015. Respectively, companies develop individ-ual improvement approaches, which makes comparison and industry benchmarking impossible. Therefore, this study establishes a COBIT 5 PAM based maturity measurement in-strument for ISO 9001 based process models, wherewith ISO 9001 certified compa-nies will be able to assess their individual process models along the standardized maturity measurement instruments of COBIT 5 PAM. This study analyses, based on a design science research approach, the current scientific and practical literature about quality management and process maturity measurement as well as that about respective combination approaches of these fields. With this foundation, a compre-hensive mapping of ISO 9001:2015 and COBIT 5 PAM needs to be defined. This map-ping then is the baseline for a prototype that allows process maturity measurement for ISO 9001 certified process models. Finally, this prototype need to be validated within a qualitative case study. Based on the combination of ISO 9001:2015 and COBIT 5 PAM on process level, the Process Improvement Prototype (PIP) is developed. This prototype covers two activ-ities, which participating companies need to perform. On the one hand, the PIP sup-ports its users when mapping their individual process maps with a generic ISO 9001:2015 process map (GPM-IT). This generalization, on the other hand, allows the execution of the PIPs second activity, whereas the measurement tools of COBIT 5 PAM are applied to define the capability level of individual ISO 9001:2015 processes and establish respective process improvement initiatives. The PIP has been validated within a practical environment together with Glaux Soft AG, a Swiss-based software development SME. Thereby, its overall usability is ap-proved by mapping Glaux Softs individual ISO 9001 processes with the generic pro-cesses of the GPM-IT and furthermore, by performing a process maturity measure-ment iteration with the PIPs tools and techniques. Thereby, certain limitations and improvement ideas are identified and either directly addressed within the study or highlighted as possible prospective research activities.
title: MRT/TRUS-Fusionsbiopsie der Prostata – die Saturation der tumorsuspekten Läsion verbessert die Detektionsrate gezielter Biopsien signifikant
Creators: name: Tschirdewahn, Stephan
name: Bonekamp, David
name: Wiesenfarth, Manuel
name: Harke, Nina
name: Kesch, Claudia
name: Püllen, Lukas
name: Guberina, Nika
name: Reis, Henning
name: Grünwald, Viktor
name: Giganti, Francesco
name: Forsting, Michael
name: Wetter, Axel
name: Hadaschik, Boris A.
name: Radtke, Jan Philipp
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die multiparametrische MRT (mpMRT) und MRT/TRUS-Fusionsbiopsien detektieren zuverlässig signifikante Prostatakarzinome (PC). Die adäquate Anzahl gezielter Biopsiezylinder zur präzisen Diagnostik ist jedoch unklar. In der vorliegenden Arbeit wurde die bioptische Saturation[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 66. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie
title: Vim3 – ein neuer serologischer Tumormarker
Creators: name: von Brandenstein, Melanie
name: Köditz, Barbara
name: Heidenreich, Axel
name: Fries, Jochen
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Prostatakarzinom (PCa) ist der am häufigsten diagnostizierte maligne Tumor in Männern. Die Bestimmung von Vim3 im Patientenserum könnte ein neuer und wichtiger Biomarker sein für die Bestimmung von biologisch aggressiven PCas. Unserer Meinung nach ist die Bestimmung der[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 66. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie
Übergangssystem stösst an Grenzen: «Mehrfachproblematiken» erfordern Kooperationen
Creators: name: Schaffner, Dorothee
name: Hirschfeld, Heidi
name: Chamakalayil, Lalitha
Publisher: name: Schweizerische Gesellschaft für angewandte Berufsbildungsforschung
Year: 2023
Subjects: subject: Übergangssystem
subject: Mehrfachproblematiken
subject: Interinstitutionelle Zusammenarbeit
subject: Bedarfsorientierung
subject: 300 - Sozialwissenschaften

description: Junge Menschen, denen «Mehrfachproblematiken» attestiert werden, haben oft keine eigenen Ressourcen oder informelle Hilfen aus dem sozialen Umfeld zur Bewältigung ihrer Probleme. Gleichzeitig sind auch die Berufsbildung und die Angebote des Übergangssystems häufig überfordert, wenn es um bedarfsorientierte Unterstützung geht. Dies zeigt eine Studie im Auftrag der Nationalen Plattform gegen Armut. Zu unübersichtlich ist die Struktur der verschiedenen Akteure, zu oft zielen diese Systeme auf eine einseitige Zielsetzung wie die Berufsintegration, auf der Strecke bleibt die soziale Integration. Die Studie macht deutlich, dass zur Umsetzung der Grundsätze einer «bedarfsorientierten Unterstützung» und «Koordination von Hilfen» Entwicklungen auf mindestens drei Systemebenen nötig sind: der strategischen Ebene, der Ebene der Fallführung und der Ebene der Fallbegleitung. Das Genfer Modellprojekt «Cité des Métiers» zeigt mögliche Ansatzpunkte.
title: 02_1628
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Thermal and chemical denaturation of Colocasia esculenta tuber agglutinin from α2β2 to unfolded state
Creators: name: Biswas, Himadri
name: Rajagopal Chattopadhyaya
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: The major tuber storage protein of Colocasia esculenta, is a monocot mannose-binding, widely used dietary lectin, containing two polypeptides of 12.0 and 12.4 kDa. By both gel filtration and dynamic light scattering at pH 7.2, the lectin has a α2β2 form of apparent molecular mass of 48.2 kDa and a hydrodynamic radius of 6.1 ± .2 nm; however, at pH 3, it migrates as αβ and has a reduced hydrodynamic radius of 4.6 ± .3 nm. Our circular dichroism spectroscopy studies show that the lectin retains approximately 100% of its secondary structure between pH 2–8, going down to ~90% for extreme acidic/alkaline conditions. The fluorescence emission maxima of 346 to 350 nm for pH 4 to 10 show that the tryptophan residues are relatively exposed. The unfolding is a simple two-state process, N4 ↔ 4U, as seen in our denaturation scan profiles. These denaturation profiles, monitored separately by fluorescence, far-UV CD, and near-UV CD, are completely super imposable. Analyses of these profiles provide an estimate of several thermodynamic parameters at each guanidinium chloride concentration, including the melting temperature Tg, which is 346.9 K in 0 M, but lowers to 321.8 K in 3.6 M. Dimeric and tetrameric interfaces observed in the crystal structure for the same protein are used to rationalize solution data in some detail.
Poster_MolecularMimicry_2017.pdf
Creators: name: Lang, Stefan
name: S. Germerodt
name: C. Glock
name: C. Skerka
name: P. F. Zipfel
name: S. Schuster
Publisher: name: figshare
Year: 2017
Subjects: subject: 10202 Biological Mathematics
subject: FOS: Mathematics
subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: Molecular mimicry is the formation of specific molecules by parasites to avoid recognition and suppression by the immune system of the host. This is analogous to uniforms misused by villains. Several pathogenic Ascomycota and Zygomycota show such a behaviour, deceiving, in particular, the innate immune system. For example,Candida albicans binds human regulators like complement factor H and, thus, hides from the complement system. Such a camouflage can reach a point where the immune system can no longer clearly distinguish between self and non-self. This implies that a trade-off between attacking possible pathogens and host cells has to be made, which can in turn lead to autoimmunity. Based on methods from signalling theory and protein-interaction modelling, we here present a model of molecular mimicry by C. albicans involving human immune regulatory factor H.
Mython akousas. Zum Grund der Dichtung bei Parmenides und Empedokles
Creators: name: Scheier, Claus-Artur
Publisher: name: Trier University
Year: 2022

description: Earliest Greek philosophy concurred with traditional poetry in its attempt to deliver cosmological thought about the Universe (τὰ πάντα); to this end, it used a paratactically descriptive prose style (Anaximander, Anaximenes). Adopted by a new kind of poetry criticizing the traditional myths as mere opinions (δόξαι) and mediated through its Pythagorean mathematization, philosophy gathers itself into its own critical principle: Identity (Xenophanes). Identity and Difference together (Heraclitus) differentiate the world-immanent Logos (λόγος ἐών). In human thought, this Logos presents itself as Judgement (κρίσις): Predication is reflected in a tropic prose style. The disentanglement of the resulting paradoxical unity of opposites calls forth the Principle of Contradiction and reinstates poetry as self-revelation of intellectual intuition (νοεῖν): while in the opinions of mortals, everything might be considered as merely asserted and ambiguous, contradiction is the ever-present presupposition in every act of thinking (Parmenides). The infinite progress of excluding contradiction (Anaxagoras) is itself dialectically shown as contradictory (Zenon): What remains is the perception of the sole, non-conceptualized phenomenon, whose apprehension existentially deepens into faith (πίστις). Linking up with pre-philosophical myth (Hesiod), it manifests itself once again as poetry, now already rhetorically (Empedocles).
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0658
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: cartulaire
subject: Chartes de la Bourgogne du Moyen Âge

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0658, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0658, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Developmental language disorders: Law enforcement (Benes & Lund, 2024)
Creators: name: Benes, Clare
name: Lund, Emily A.
Publisher: name: ASHA journals
Year: 2024
Subjects: classificationCode: 420110
subject: Speech pathology
classificationCode: 480401
subject: Criminal law

description: Purpose: The purpose of this study was to pilot test a survey of professionals within the justice system about their knowledge and perceptions of developmental language disorders (DLDs) and to gather initial data supporting their knowledge and perceptions.Method: One hundred thirty-six adults in Texas with law enforcement jobs, primarily police officers, participated in this study. Participants completed a survey consisting of 78 questions about their background, experiences with DLD, and beliefs about communication. Additionally, 42 adults who did not work in law enforcement completed the survey twice to establish the initial measures of survey reliability.Results: This survey demonstrated sufficient test–retest reliability with adults not in law enforcement, and results indicated the emergence of two subscales within the survey. Law enforcement professionals appeared to have limited knowledge of DLD, and many linked language-related behaviors with credibility. A majority did agree with giving accommodations to individuals who struggle with language and reported interest in receiving training to recognize and accommodate DLD.Conclusions: This pilot study demonstrates a need for collaboration between speech-language pathologists and law enforcement professionals and provides data for a survey that could be used across professional groups in the justice system to measure knowledge and perspectives of DLDs. This work represents an initial step in an iterative process of survey development for law enforcement professionals.Supplemental Material S1. Survey.Benes, C., & Lund, E. (2024). Knowledge and perspectives of developmental language disorders: The pilot development of a survey of professionals working in law enforcement. American Journal of Speech-Language Pathology, 33(2), 969–989. https://doi.org/10.1044/2023_AJSLP-22-00374
Access to water and sanitation infrastructures for primary schoolchildren in the south-central part of Côte d’Ivoire
Creators: name: Kouame, Parfait
name: Galli, Anais
name: Peter, Maryna
name: Loss, Georg
name: Wassa, Diriassouba
name: Bonfoh, Bassirou
name: Utzinger, Jürg
name: Winkler, Mirko
Publisher: name: MDPI
Year: 2021
Subjects: Côte d’Ivoire
Drinking water
Primary schools
Schoolchildren
Water
Sanitation
Hygiene (WASH)

description: In rural settings of Côte d’Ivoire, access to water, sanitation, and hygiene (WASH) at schools is often lacking. The purpose of this study was to assess the availability, quality, and use of WASH infrastructure in schools in the south-central part of Côte d’Ivoire, and to determine the hygiene practices of schoolchildren. A cross-sectional study was conducted in 20 primary schools with (n = 10) or without (n = 10) direct access to drinking water. The survey was comprised of a questionnaire directed at schoolchildren aged 8–17 years, an assessment of the WASH infrastructure, and the testing of drinking water samples for Escherichia coli and total coliforms. Overall, 771 schoolchildren were enrolled in the study. One out of four children (24.9%) reported that they used available toilets. Among those children not using toilets, more than half (57.5%) reported that they practised open defecation. Drinking water infrastructure was limited in most schools because of poor storage tanks, the low flow of water, or broken wells. All drinking water samples (n = 18) tested positive for total coliforms and 15 (83.3%) tested positive for E. coli. The lack of WASH infrastructures in primary schools in the south-central part of Côte d’Ivoire, in combination with poor hygiene practices, might govern disease transmission and absenteeism at school, especially among females.
The Poet as Fate: Schopenhauer’s Literary Vision
Creators: name: Dowthwaite, James
Publisher: name: Trier University
Year: 2022

description: The claim that a thinker concerned with the development of a totalizing metaphysical system can be a literary philosopher may seem hard to justify. For Arthur Schopenhauer, the entire world is the representation or appearance of the will to life, the metaphysical essence of all being. And yet, because this will must always appear and always take form, it is only formally that we can grasp it, only in concrete instances. For this reason, the poet “shows us how the will behaves under the influence of motives and reflection. He presents us this for the most part in the most perfect of its appearances” (WWRII, 310). In this paper, I will argue that Schopenhauer founds a philosophical approach which comes to rest on literary foundations and which alights at key moments on the strength of his literary as well as his philosophical forebears. I will do this by means of looking at how Schopenhauer treats the concept of fate. It is my contention that the fatalism inherent in Schopenhauer’s ethics is a direct result of a fundamentally literary approach to the concept. This enables us to conceive of fate from a literary and not solely from a metaphysical standpoint. I will begin by outlining the place of the literary in Schopenhauer’s philosophy, including a brief account of those writers whose work he incorporates into his analysis, and then I will demonstrate its relation to his fatalism.
Beobachtungsbogen zur Beurteilung der Arbeitsfähigkeit: Ein arbeitsdiagnostisches Hilfsmittel für die berufliche Eingliederung
Creators: name: Wagner, Andrea Lara
Publisher: name: Hochschule für Angewandte Psychologie FHNW
Year: 2022
Subjects: Arbeitsfähigkeit
Messinstrument
Beurteilung
Arbeitsdiagnostik
berufliche Eingliederung

description: Die vorliegende Arbeit befasst sich mit der Beurteilung der Arbeitsfähigkeit von Menschen, die für einen Einstieg oder Wiedereinstieg ins Berufsleben trainieren. Auf Basis des „Kreises der Arbeitsfähigkeit“ und der „Hilfen zur Befunderhebung/Arbeitsdiagnostik“ nach Köser (2019) wurde für die berufliche Eingliederung der BBI Züri West ein Beobachtungsbogen entwickelt. Die Objektivität (Beobachterunabhängigkeit) wird durch die Standardisierung des Beobachtungsbogens eingehalten. Die Reliabilität (Beobachterübereinstimmung) wurde mit 12 Beobachterpaaren geprüft und erreichte durchschnittlich einen mittleren Effekt τ = .37, p .055 (Korrelationswert nach Kendall-Tau und unter Ausschluss eines Ausreissers). Die Validität wurde geprüft mit den Daten einer systematischen Literaturanalyse sowie Experteninterviews und kann lediglich im Bereich der „individuellen Faktoren“ der Arbeitsfähigkeit eingehalten werden. 11 Fachpersonen der beruflichen Integration beurteilten das Verfahren abschliessend mit einer mittleren Akzeptanz. Damit die Arbeitsfähigkeit als Ganzes beurteilt werden kann, bedarf es einer Erweiterung durch die Beurteilung von Kontextfaktoren und gesundheitlichen Aspekten.
Best-worst scaling to assess the most important barriers and facilitators for the use of health technology assessment in Austria
Creators: name: Feig, Chiara
name: Cheung, Kei Long
name: Hiligsmann, Mickaël
name: Evers, Silvia M. A. A.
name: Simon, Judit
name: Mayer, Susanne
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Background: Although Health Technology Assessment (HTA) is increasingly used to support evidence-based decision-making in health care, several barriers and facilitators for the use of HTA have been identified. This best-worst scaling (BWS) study aims to assess the relative importance of selected barriers and facilitators of the uptake of HTA studies in Austria. Methods: A BWS object case survey was conducted among 37 experts in Austria to assess the relative importance of HTA barriers and facilitators. Hierarchical Bayes estimation was applied, with the best-worst count analysis as sensitivity analysis. Subgroup analyses were also performed on professional role and HTA experience. Results: The most important barriers were ‘lack of transparency in the decision-making process’, ‘fragmentation’, ‘absence of appropriate incentives’, ‘no explicit framework for decision-making process’, and ‘insufficient legal support’. The most important facilitators were ‘transparency in the decision-making process’, ‘availability of relevant HTA research for policy makers’, ‘availability of explicit framework for decision-making process’, ‘sufficient legal support’, and ‘appropriate incentives’. Conclusion: This study suggests that HTA barriers and facilitators related to the context of decision makers, especially ‘policy characteristics’ and ‘organization and resources’ are the most important in Austria. A transparent and participatory decision-making process could improve the adoption of HTA evidence.
Lettre de Giovan Jacopo Dionisi à Jean-François Séguier, 1778-05-26
Creators: name: Dionisi, Giovan Jacopo
name: Dionisi, Giovan Jacopo
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021

description: [transcription] Monsieur

Verona 26 maggio 1778

Quando ho spedito i due libri da me ultimamente dati alla luce, con una mia [...] a V.S. Ill.ma, non avea per anche avuto dal Padre da Prato la lettera sua per lei in risposta delle commissioni da lui eseguite per parte sua, di cui ne ho partecipato ancor io delle grazie sue nel suo bellissimo libro sopra la maison carrée. Io mi consolo di nuovo [...] di si bel libro, e della felice divinazione [...], che non puo' essere nè più giusta, nè più veritiera. Monsig. Suarez anch`esso ha trattato questo punto. Joseph. Mariae Suaresii De foraminibus lapidum in priscis aedificiis, e le avrebbe dato molto per illustrar affatto il suo punto.

Siamo dietro ad una nuova edizione delle opere del Zeno che veramente ne abbisogna. Non so se ella abbia avuto o da me o per altri alcune emendazioni arischiate per saggio del nostro arciprete Perazzini con suoi due libri. Se non le avesse mi avvisi, che gliele spediro' di nuovo. Il mal è che dopo la morte del buon nostro arciprete Muselli e specialmente del marchese Maffei Verona non è più Verona ed io mi vado ingegnando di tener viva l'antichità e le cose della patria; ma non v`è chi mi dia braccio ed aiuto, e solo non si puo' far cosa di buono; e solo piccole cose e strozzate si puo' dare per non lasciar un tal studio totalmente in abbandono. I tempi felici sono passati, e ci vuol pazienza e rabbia. Finisco per ora, col dimandarle scusa della libertà dello scrivere e dell'incivile foglio che per la necessità della contenanza mi conviene di usare, e qui con piena stima ed amicizia mi conservo

De vous monsieur

Devotissimo ed obligatissimo servitore

Jio Jiacopo Dionisi canonico

[fol. 16v]

A Monsieur Jean-Francois Seguier de l'Academie royale de Nismes etc.

A Nismes

Turin
description: [personnes citées] Bartolomeo Perazzini, Giovanni Francesco (archiprêtre) Muselli, Girolamo Da Prato, Joseph-Marie, évêque de Vaison Suarez, Scipione Maffei
description: [reférence bibliographique citée] Suarez, Joseph Maria, Diatriba de foraminibus lapidum in priscis aedificiis, Lugduni, apud G. Barbier, 1652.
. Le opere di S. Zenone volgarizzate dal marchese Gio. Jacopo Dionisi canonico veronese, Verona, Dionigi Ramanzini, 1784.
. Séguier, Jean-François, Dissertation sur l'ancienne inscription de la Maison-carrée de Nismes, Nimes, Gaude, 1776.
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 312_2, fol. 16
description: Source: ark:/12148/btv1b100159238
Insight into the Shortage of Food Aniinal Veterinarians
Creators: name: Schmitz, John A. (Jack)
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: A survey of Nebraska veterinarians was conducted to study factors that influence veterinarians in their choice of practice type and location, e.g. food animal or small animal veterinary practice, and the type of community where they practice, i.e. urban or rural. Objectives of the study were to determine if possible veterinary college admission criteria could be identified to improve selection of students that will ultimately pursue food animal and rural practices, and whether programs in veterinary medical colleges significantly influenced food animal and rural veterinary practice decisions of these graduates. Background characteristics significantly associated with food animal practice included: male, grew up on a working farm or ranch, parents had livestock, hometown population of 10,000 or less, and interest in food animal practice at time of admission to veterinary medical college.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006
Hypothesis 1
Creators: name: Harper, Madeline
name: Colley, Kelsie
name: Colley, Kelsie
name: Munk, Kennedy
name: Parisi, Skye
Publisher: name: OSF Registries
Year: 2022

description: Students are more likely to have worse self-perception if they cheat on their own academic work. This hypothesis has a negative directionality. The predicted effect is that their self-perception is lower.
The Copenhagen Invitation
Creators: name: Allen, Jamie
Publisher: name: Continent
Year: 2015
Subjects: subject: metaphors
subject: media
subject: geology
subject: 700 - Künste und Unterhaltung

description: What is a metaphor for? We might first assume that these unassuming little devices are fixers against incomprehension. They are often translative, mnemonics tricks, linguistically metamorphosing the unknown of a murky, muddy idea into to the crystalline clarity of the familiar. Language itself functions analogously — ”that is a chair” solidifies reference, subtended by tradition, culture and practice, from a concrete object to a gaseous concept, and sublimating back again. “No ideas but in things,” wrote W.C. Williams. (Duffey, Litz, & MacGowan, 1987) Karan Barad inverts this relation with her own rejoinder: “Language matters. Discourse matters. Culture matters. There is an important sense in which the only thing that does not seem to matter anymore is matter.” (Micciche, 2014)
The Use of Ultrasound in Cow/Calf Applications
Creators: name: Stroud, Brad
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2006

description: Transrectal guided real-time ultrasound has been used extensively to diagnose reproductive scenarios in the bovine female for almost 20 years. Uterine diagnoses include early pregnancy, multiple pregnancies, sex of the fetus, exudates in the uterine lumen, early embryonic death, stage of the estrous cycle (estrus vs. diestrous), and other abnormal conditions. Ovarian diagnoses include follicular dynamics, stage of estrous cycle (estrus vs. diestrous), presence or absence of corpora lutea, cystic ovarian disease, response to super stimulation of donors at estrus and diestrous, ovarian tumors, polycystic ovaries, and anestrous vs. cycling females. In addition, ultrasound has been used as an instrument for collecting oocytes for in vitro fertilization. This paper reviews the procedures, discusses the efficacy of the diagnoses of the various conditions, and reflects on the scenarios most commonly encountered in bovine practice. The learning curve for using ultrasound will also be thoroughly reviewed.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2006