cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Two essays in merger clauses
Creators: name: Wu, Ge
Publisher: name: No Publisher Supplied
Year: 2018

description: This dissertation studies the impact of merger clauses. Merger clauses allocate the risks between the target and the bidder, share information among different parties in the deal and manage the negotiation process and disputes.In the first essay, I look at reverse termination fees (henceforth, referred to as RTFs). RTFs are required payments by bidders when they “walk away” from a merger or acquisition, and vary significantly in size and design. I find inefficient RTFs correlate with lower bidder returns, even in a subsample where disclosure of RTF terms lags deal announcements by more than two days. I also find inclusion of certain RTFs in consolidating industries reveals private information to the market, resulting in negative abnormal returns. Finally, I find a negative significant relationship between the probability of deal completion and inefficient and negative signal RTFs, consistent with the fact that deals with inefficiently designed RTFs signal the bidder’s lower commitment to the current deal and deals with negative signal RTFs are adopted in consolidating industries where both deal competition and antitrust issues are higher than in other deal settings.In the second essay, I construct merger clauses indices based on legal scholars’ ex-ante prediction and examine the relationship between announcement returns and different types of merger clauses. I find that bidder protective clauses correlate with higher bidder returns while target protective clauses and pro-competition clauses correlate with higher target returns. I also find that bidder and target protective indices have larger impacts on announcement abnormal returns for “bad” deals than for “good” deals. Finally, I find that the inclusion of more bidder protective clauses leads to lower deal completion rates while the inclusion of more target protective clauses and pro-competition clauses has no impact on deal completion rates. These results are consistent with the expert lawyer/efficient contracting view of Cain, Macias, and Davidoff Solomon (2014), and Coates (2016), and against merger contracts as boilerplate agreements.
How robust are particle physics predictions in asymptotic safety?
Creators: name: Kotlarski, Wojciech
name: Kowalska, Kamila
name: Rizzo, Daniele
name: Sessolo, Enrico Maria
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The framework of trans-Planckian asymptotic safety has been shown to generate phenomenological predictions in the Standard Model and in some of its simple new physics extensions. A heuristic approach is often adopted, which bypasses the functional renormalization group by relying on a parametric description of quantum gravity with universal coefficients that are eventually obtained from low-energy observations. Within this approach a few simplifying approximations are typically introduced, including the computation of matter renormalization group equations at 1~loop, an arbitrary definition of the position of the Planck scale at $10^{19}$ GeV, and an instantaneous decoupling of gravitational interactions below the Planck scale. In this work we systematically investigate, both analytically and numerically, the impact of dropping each of those approximations on the predictions for certain particle physics scenarios. In particular we study two extensions of the Standard Model, the gauged $B-L$ model and the leptoquark $S_3$ model, for which we determine a set of irrelevant gauge and Yukawa couplings. In each model, we present numerical and analytical estimates of the uncertainties associated with the predictions from asymptotic safety.
description: 37 pages, 6 figures, 2 tables. Added sec. 3.4 on relevant abelian gauge couplings. Matches published version
Latent semantics of action verbs reflect phonetic parameters of intensity and emotional content
Creators: name: Petersen, Michael Kai
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences
subject: I.2.4; I.2.7
subject: 68T50

description: Conjuring up our thoughts, language reflects statistical patterns of word co-occurrences which in turn come to describe how we perceive the world. Whether counting how frequently nouns and verbs combine in Google search queries, or extracting eigenvectors from term document matrices made up of Wikipedia lines and Shakespeare plots, the resulting latent semantics capture not only the associative links which form concepts, but also spatial dimensions embedded within the surface structure of language. As both the shape and movements of objects have been found to be associated with phonetic contrasts already in toddlers, this study explores whether articulatory and acoustic parameters may likewise differentiate the latent semantics of action verbs. Selecting 3 x 20 emotion, face, and hand related verbs known to activate premotor areas in the brain, their mutual cosine similarities were computed using latent semantic analysis LSA, and the resulting adjacency matrices were compared based on two different large scale text corpora; HAWIK and TASA. Applying hierarchical clustering to identify common structures across the two text corpora, the verbs largely divide into combined mouth and hand movements versus emotional expressions. Transforming the verbs into their constituent phonemes, the clustered small and large size movements appear differentiated by front versus back vowels corresponding to increasing levels of arousal. Whereas the clustered emotional verbs seem characterized by sequences of close versus open jaw produced phonemes, generating up- or downwards shifts in formant frequencies that may influence their perceived valence. Suggesting, that the latent semantics of action verbs reflect parameters of intensity and emotional polarity that appear correlated with the articulatory contrasts and acoustic characteristics of phonemes
description: 15 pages
Additional file 1 of Determinants of the implementation of eHealth-based long-term follow-up care for young cancer survivors: a qualitative study
Creators: name: Stamer, Tjorven
name: Traulsen, Pia
name: Rieken, Johannes
name: Schmahl, Teresa
name: Menrath, Ingo
name: Steinhäuser, Jost
Publisher: name: figshare
Year: 2024
Subjects: Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 1
Dynamics of tilted Bianchi models of types III, IV, V in presence of diffusion
Creators: name: Shogin, Dmitry
name: Hervik, Sigbjørn
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We investigate the three types of class B Bianchi cosmologies filled with a tilted perfect fluid undergoing velocity diffusion in a scalar field background. We consider the two most importantcases: dust and radiation. A complete numerical integration of the Einstein field equations coupled with the diffusion equations is done to demonstrate how the presence of diffusion can affect the dynamics of cosmological evolution, where the most attention is paid to changes to the late-time behaviour. We show that aside from quantitative effects, diffusion can result in significant qualitative differences. For example, the cosmologies may recollapse if diffusion is sufficiently strong, or evolve towards the de Sitter state otherwise. In constrast to the diffusionless case, radiation isotropizes in presence of diffusion, and the tilt decreases exponentially at later times: $V\sim e^{-0.25τ}$; also, we determine the decay rates of energy density, which become slower when the diffusion term is non-zero.
description: 26 pages, 8 figures
Role of cGMP as second messenger of adenosine in the inhibition of renin release
Creators: name: Kurtz, Armin
name: Della Bruna, R.
name: Pfeilschifter, J.
name: Bauer, Christian
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Adenosine/physiology
subject: Animals
subject: Calcium/metabolism
subject: Cells, Cultured
subject: Cyclic AMP/metabolism
subject: Cyclic GMP/physiology
subject: Cytoplasm/metabolism
subject: Juxtaglomerular Apparatus/metabolism
subject: Kidney/metabolism
subject: Rats
subject: Renin/secretion

description: Adenosine is known to be a potent inhibitor of renin release from the kidneys. The aim of this study was to investigate the transmembrane signalling avenue that the second messenger of adenosine causes inhibition of renal renin release. Using short term cultures of juxtaglomerular cells isolated from rat kidneys, we found that adenosine inhibited spontaneous renin release from these cells up to 40% of control, in a dose dependent fashion between 10(-10) M to 10(-6) M. Half maximal inhibition was observed at 2 X 10(-8) M adenosine. The inhibitory effect of adenosine on renin release could be mimicked by the A1-receptor agonist N6-cyclohexyladenosine (CHA) and could be attenuated by the A-receptor antagonist theophylline (5 X 10(-5) M). The A2-receptor agonist 5'-N-ethylcarboxamideadenosine (NECA) had no inhibitory effect on renin release. These findings indicate that the inhibitory effect of adenosine is mediated by A1-receptors on juxtaglomerular cells. Adenosine had no effect on either transmembrane calcium influx or the cytosolic free calcium concentration in the isolated juxtaglomerular cells. Adenosine also did not alter the cellular level of cyclic AMP in the concentration range employed. However, adenosine led to a dose dependent increase of the cellular level of cyclic GMP. Half maximal increase of cGMP was observed at 10(-8) M adenosine. The effect of adenosine on cyclic GMP could be mimicked by the A1-receptor agonist CHA and could be attenuated by the A-receptor antagonist, theophylline.(ABSTRACT TRUNCATED AT 250 WORDS)
Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure
Creators: name: Kindler, J.
name: Eckardt, Kai-Uwe
name: Ehmer, B.
name: Jandeleit, K.
name: Kurtz, Armin
name: Schreiber, A.
name: Scigalla, P.
name: Sieberth, H. G.
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Adult
subject: Aged
subject: Dose-Response Relationship, Drug
subject: Erythropoietin/pharmacokinetics
subject: Female
subject: Glomerular Filtration Rate
subject: Humans
subject: Injections, Intravenous
subject: Kidney Failure, Chronic/therapy
subject: Kidney Function Tests
subject: Male
subject: Middle Aged
subject: Recombinant Proteins/pharmacokinetics

description: The pharmacokinetic profile of recombinant human erythropoietin (rHuEpo) was studied after a single intravenous dose of 150 U/kg in ten patients with various degrees of renal function: group I, creatinine clearance greater than 80 ml/min, n = 2; group II, creatinine clearance 10-50 ml/min, n = 6; group III, creatinine clearance less than 3 ml/min (patients undergoing haemodialysis) n = 2. Erythropoietin concentrations in serum and urine samples obtained over 48 h were measured by RIA. rHuEpo was cleared from circulation in an exponential fashion, the half-life ranged from 6.5 to 12.7 h (mean 9.03 h) and was not different between the groups. The apparent volume of distribution varied from 0.041 to 0.099 l/kg (mean 0.070 l/kg) this corresponds to 1.5 times the plasma volume and was unrelated to kidney function. Renal clearance (groups I, II) accounted for less than 3% of total body clearance, both parameters were unaffected by decreasing renal function. These results indicate that, in accordance with animal data, the elimination of rHuEpo occurs mainly through non-renal mechanisms.
Citizen centric stakeholder theory
Creators: name: Yaqub, Ussama
Publisher: name: No Publisher Supplied
Year: 2018

description: In a relatively short period of time, social media has gained significant importance as a mass communication and public engagement tool. Rapid dissemination of information through social media platforms such as Facebook and Twitter, provides individuals and organizations with the ability to broadcast their message to a wide audience instantly and directly. Hence, we now witness almost all public and private organizations with a presence on popular social networks. However, unlike conventional media, social media allows users to wield tremendous influence over popular discussion topics and events. While in traditional media, the narrative is built by a group of established influencers, discussions remain fluid and decentralized on social networks. Although some users do wield more sway than others, all citizens utilizing the platform are stakeholders who have to be recognized and managed if any entity wishes to use these platforms to carry out their mission. The primary goal of this research is to perform analysis of the social media data to gain insights and to better understand the nature of the discourse taking place on popular social media platforms and how sentiment, keywords and users impact these discussions. Such understanding is important to enable prime movers of social media to accurately identify and engage their stakeholders, enabling them to foster more meaningful communication with online social network users.Towards this end, this dissertation has made the following contributions: First, it has developed a framework to analyze social media usage by adopting the time tested stakeholder theory for social media. It has proposed a Citizen Centric Stakeholder Theory for Social Media, where all users of social media platforms are treated as stakeholders. Second, it has utilized the above framework to investigate the nature and characteristics of social media usage by citizens from around the world. It has evaluated this participation through sentiment and user behavior analysis. As a case study, this dissertation has applied this citizen centric stakeholder theory to analyze Twitter data gathered during US Presidential Elections of November 2016 and UK General Elections of June 2017. Third, it has evaluated the social media communication of public sector organizations operating in the Northeast US to understand their communication strategy in terms of sentiment and message content. Fourth, it has studied the subjectivity and polarity of Twitter data with respect to the location of Tweets. Finally, a web-based system for geospatial visualization of current sentiments associated with a hashtag or word in Twitter messages has been developed.
Evaluation of the stability of human erythropoietin in samples for radioimmunoassay
Creators: name: Eckardt, Kai-Uwe
name: Kurtz, Armin
name: Hirth, P.
name: Scigalla, P.
name: Wieczorek, L.
name: Bauer, Christian
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Anemia, Aplastic/blood
subject: Blood Preservation/standards
subject: Erythropoietin/blood
subject: Freezing
subject: Humans
subject: Kidney Failure, Chronic/blood
subject: Polycystic Kidney Diseases/blood
subject: Radioimmunoassay/methods
subject: Reference Standards
subject: Renal Dialysis

description: Radioimmunoassays for erythropoietin are limited so far to a few specialized laboratories and this requires transport and storage of samples. We therefore tested the stability of immunoreactive erythropoietin in serum and plasma samples obtained from a uremic and a nonuremic anemic patient. No significant change in the concentration of immunoreactive erythropoietin was found in either serum or plasma samples for up to 14 days of storage. This type of stability was observed no matter whether the samples were stored at room temperature, 4 degrees C, or -20 degrees C. There was no difference between the estimates of erythropoietin in serum and heparinized plasma. Validity of the radioimmunoassay used in this study was demonstrated by parallelism of dilution curves of test specimens and the 2nd International Reference Preparation for erythropoietin and by a close correlation between the immunoreactivity and the bioactivity of the hormone, as assessed in the same samples by the exhypoxic polycythemic mouse bioassay. In conclusion the data obtained clearly indicate that the necessity of storage and transport of clinical samples does not limit the practicability of the radioimmunoassay for erythropoietin.
Position momentum Duality in the Entanglement Spectrum of Free Fermions
Creators: name: Lee, Ching Hua
name: Ye, Peng
name: Qi, Xiao-Liang
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Other Condensed Matter (cond-mat.other)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose an exact equivalence between the entanglement spectra of two completely different free-fermion systems at zero temperature. This equivalence follows from a position-momentum duality where the physical roles of the occupied band and real space projectors are exchanged. We examine the physical consequences of this duality in multi-band models, and as an example also physically motivate the equivalence of the entanglement spectrum of a real space partitioned two-band topological insulator with that of a bilayer Fermi gas with an interlayer partition. This duality has an interesting relation with the Wannier Spectrum in the high-temperature limit, and can also be extended to other basis-independent physical quantities like particle-number fluctuations.
description: 6 pages, 3 figures
Can a variation of Fine Structure Constant influence the fate of Gravitational Collapse?
Creators: name: Chakrabarti, Soumya
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that it is possible to steer clear of a spacetime singularity during gravitational collapse by considering the time-variation of a fundamental coupling, in this case, the fine structure constant α. We study a spherical distribution of cold dark matter coexisting with other fluid elements, collapsing under its own gravity. Dark matter is written as a scalar field interacting with electrically charged matter. This leads to a time variation of α and as a consequence, a breakdown of local charge conservation within the sphere. The exterior has no such field and therefore, Einstein's GR and standard equivalence principles remain valid. We derive the lowest possible bound on the collapse of this sphere beyond which there is a bounce and dispersal of most of the accumulated matter. We discuss the critical behavior of the system around this point and show that the bound is connected to a length scale of the order of Planck, introduced in theory for dimensional requirements.
description: 12 pages, 9 Figures
Physical limitations to the spatial resolution of solid-state detectors
Creators: name: Boronat, M.
name: Marinas, C.
name: Frey, A.
name: Garcia, I.
name: Schwenker, B.
name: Vos, M.
name: Wilk, F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: In this paper we explore the effect of $δ$-ray emission, fluctuations in th e signal deposition on the detection of charged particles in silicon-based detec tors. We show that these two effects ultimately limit the resolution that can be achieved by interpolation of the signal in finely segmented position-sensitive solid-state devices.
description: 5 pages
Additional file 2 of Determinants of the implementation of eHealth-based long-term follow-up care for young cancer survivors: a qualitative study
Creators: name: Stamer, Tjorven
name: Traulsen, Pia
name: Rieken, Johannes
name: Schmahl, Teresa
name: Menrath, Ingo
name: Steinhäuser, Jost
Publisher: name: figshare
Year: 2024
Subjects: Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 2
Bestimmungsmethoden für Erythropoietin [Assay methods for erythropoietin]
Creators: name: Kurtz, Armin
name: Eckardt, Kai-Uwe
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Animals
subject: Biological Assay
subject: Dose-Response Relationship, Drug
subject: Erythropoiesis/drug effects
subject: Erythropoietin/pharmacology
subject: Immunoassay
subject: Mice
subject: Rats

description: The aim of this contribution is to briefly characterize the assays available for the quantitation of erythropoietin (EPO). The radioimmunological determination of EPO has gained priority for routine and screening measurements. The in vivo bioassay is the most reliable assay for biologic EPO activity. In vitro bioassays should be limited to situations in which radioimmunoassays are not available and for which in vivo bioassays are too insensitive.
Rat juxtaglomerular cells are endowed with DA-1 dopamine receptors mediating renin release
Creators: name: Kurtz, Armin
name: Della Bruna, R.
name: Pratz, J.
name: Cavero, I.
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Animals
subject: Benzazepines/pharmacology
subject: Blood Pressure/drug effects
subject: Decerebrate State
subject: Dopamine/pharmacology
subject: Fenoldopam
subject: Isoproterenol/pharmacology
subject: Juxtaglomerular Apparatus/metabolism
subject: Male
subject: Phentolamine/pharmacology
subject: Rats
subject: Rats, Inbred Strains
subject: Receptors, Dopamine/metabolism
subject: Renin/secretion
subject: Sulpiride/pharmacology
subject: Vasodilator Agents/pharmacology

description: Under control conditions a primary culture containing about 80-90% of granular juxtaglomerular (JG) cells prepared from rat kidneys continuously released renin into the culture medium at a rate of 17.9 +/- 1.4 ng angiotensin I/h per mg of cell proteins per 30 min (n = 14). Dopamine (1.0 microM), the DA-1 dopamine receptor agonist fenoldopam (0.5 microM), and isoproterenol (1.0 microM) increased renin secretion markedly (130-200%). Propranolol (0.1 microM) reduced the effects of isoproterenol significantly (80%), but not those of dopamine or fenoldopam. In contrast, SCH 23390 (0.01 microM), a DA-1 dopamine receptor antagonist, inhibited markedly only the renin release evoked by the latter two agonists, whereas S-sulpiride (10 microM), a DA-2 dopamine receptor antagonist, and phentolamine (10 microM), a nonselective alpha-adrenoceptor antagonist, did not modify the effects of either dopamine or fenoldopam. In rats, pithed to eliminate reflexogenic mechanisms regulating renin release, at the end of a 15 min i.v. infusion of fenoldopam (20 micrograms/kg per min) there was a significant increase in plasma renin activity. This effect was completely prevented by SCH 23390 (0.1 mg/kg i.v.) but not significantly changed by S-sulpiride (0.3 mg/kg i.v.) or phentolamine (3.0 mg/kg i.v.) plus propranolol (0.75 mg/kg i.v.). In conclusion, these results indicate that DA-1 dopamine receptors are present in rat kidney JG cells and that pharmacological stimulation of these receptors with dopamine or fenoldopam leads to renin secretion.
Regulation der Erythropoietin-Bildung [Regulation of erythropoietin synthesis]
Creators: name: Bauer, Christian
name: Kurtz, Armin
name: Eckardt, Kai-Uwe
name: Tannahill, L.
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Animals
subject: Anoxia/blood
subject: Diuretics/pharmacology
subject: Erythropoietin/genetics
subject: Humans
subject: Kidney/physiology
subject: Mice
subject: RNA, Messenger/genetics
subject: Rats
subject: Time Factors

description: The main regulatory hormone for the control of erythropoiesis is erythropoietin (EPO). This glycoprotein has a molecular weight of 34,000 daltons, about 40% of which is represented by carbohydrates. EPO leads to an enhanced mitosis and differentiation of erythroid precursors (colony-forming unit erythroid) in the bone marrow by binding to specific receptors. The major stimulus for EPO formation in the kidney is hypoxia. The tubular parts that are intimately involved in this O2-sensing mechanism are the proximal tubular cells as can be inferred from the use of site-specific transport inhibitors. The minimal time necessary for a hypoxic signal to induce EPO formation was found to be 30 min, including wash out of oxygen stores, activation of the EPO gene and equilibration of the EPO distribution space. About 1.5 h after the onset of hypoxia, EPO mRNA was found to accumulate in the kidney, thus pointing toward the possibility of an oxygen-regulated transcription or oxygen-dependent regulation of the stability of EPO mRNA. Possibly, a decrease in the intracellular calcium concentration is involved in this signalling process.
Tidal Love numbers of a nonexotic compact object with a thin shell
Creators: name: Yang, Rui-Xin
name: Xie, Fei
name: Liu, Dao-Jun
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: As a possible alternative to black holes, horizonless compact objects have significant implications for gravitational-wave physics. In this work, we utilize the standard linearized theory of general relativity to calculate the quadrupolar tidal Love numbers of a nonexotic compact object with a thin shell proposed by Rosa and Piçarra. It is found that both types of tidal Love numbers are positive and increase with the initial radius for almost all values of the compactness parameter. Furthermore, they have an unexpected upper bound and vanish in the most compact configurations. As a result, this model is indeed a suitable mimicker of a black hole. However, we also observed that the speed of sound within the fluid on the shell diverges in the black hole limit.
description: 7 two-column pages, 3 figures; v2: typos corrected; v3: matching the published version in PRD
Erythropoiese und Serumerythropoietinkonzentration vor und nach Nierenallotransplantation [Erythropoiesis and serum erythropoietin concentrations before and after kidney allotransplantation]
Creators: name: Keusch, G.
name: Kurtz, Armin
name: Fehr, J.
name: Eckardt, Kai-Uwe
name: Frei, D.
name: Bauer, Christian
name: Binswanger, U.
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Erythropoiesis
subject: Erythropoietin/blood
subject: Hematocrit
subject: Humans
subject: Kidney Transplantation
subject: Radioimmunoassay
subject: Renal Dialysis
subject: Reticulocytes/analysis
subject: Time Factors

description: Hematological parameters and serum erythropoietin (EPO) levels were measured before and sequentially after grafting in 50 consecutive cadaver renal transplant recipients. EPO was estimated using a sensitive radioimmunoassay. Values for nonanemic controls were 15-25 mU/ml. Mean hematological values before transplantation were as follows: hemoglobin 9.7 +/- 2.4 g/dl; hematocrit 29 +/- 8%; corrected reticulocytes count 15 +/- 8% and EPO 29 +/- 23 (11-131) mU/ml. In the entire studied population, 35 patients had inadequate low EPO levels for their degree of anemia. In the whole population, there was a significant positive exponential correlation between EPO and hematocrit (r = 0.31; p less than 0.05). In the subset of patients with underlying cystic kidney disease and in hemodialysis patients treated with recombinant human EPO, hemoglobin, hematocrit and EPO levels were higher when compared to hemodialysis or CAPD patients with other kidney diseases. Following successful renal transplantation, EPO increased to 45 +/- 31 mU/ml at 1 month and then decreased to 25 +/- 18, 18 +/- 7 and 19 +/- 4 mU/ml at 3,6 and 9 months, respectively. Within the 1st month after transplantation there was a 4-fold increase in reticulocytes from 9 +/- 5 to 38 +/- 14%, followed by a slow decrease over the next several months to 23 +/- 11% at 9 months. In contrast, the hematocrit level rose more gradually from 28 +/- 7 to 44 +/- 6% at 9 months. In 25 of 36 patients with a functioning graft who were followed for more than 6 months, anemia was corrected and 11 patients remained slightly anemic with a mean hematocrit level of 36 +/- 4%.
Developing Optimization-Based Inverter Models for Short Circuit Studies
Creators: name: Mabote, Thabiso R.
name: Tabarez, Jose E.
name: Barnes, Arthur K.
name: Mate, Adam
name: Bent, Russell W.
name: Cotilla-Sanchez, Eduardo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: As inverter-based generation becomes more common in distribution networks, it is important to create models for use in optimization-based problems that accurately represent their non-linear behavior when saturated. This work presents models for grid-following and grid-forming inverters, and demonstrates their use in optimization-based fault studies. The developed models are shown to provide results in line with experimental tests from literature; however, grid-forming inverter models fail to provide feasible solutions for certain fault types even when currents, voltages, and powers from the models seem reasonable. This work lays down the foundation for the development of relaxed models for both grid-following and grid-forming inverter models for use in optimization problems.
description: 6 pages. 13 figures
Insulin-like growth factor I stimulates erythropoiesis in hypophysectomized rats
Creators: name: Kurtz, Armin
name: Zapf, J.
name: Eckardt, Kai-Uwe
name: Clemons, G.
name: Froesch, E. R.
name: Bauer, C.
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Animals
subject: Body Weight/drug effects
subject: Erythrocyte Count
subject: Erythropoiesis/drug effects
subject: Erythropoietin/blood
subject: Growth Hormone/pharmacology
subject: Hematocrit
subject: Hypophysectomy
subject: Insulin-Like Growth Factor I/pharmacology
subject: Male
subject: Rats
subject: Recombinant Proteins/pharmacology
subject: Reticulocytes
subject: Somatomedins/pharmacology

description: Stimulation of erythropoiesis during growth is necessary to ensure proportionality between erythrocyte mass and body mass. However, the way by which erythrocyte formation is adapted to body growth is still unknown. Growth arrest in hypophysectomized rats is accompanied by decreased erythropoiesis. We have, therefore, examined whether insulin-like growth factor I (IGF-I), the mediator of growth hormone effects on body growth, is able to restore erythropoiesis in these animals. Subcutaneous infusions of 120 micrograms of recombinant human IGF-I per day in hypophysectomized rats led to increases in body weight, 59Fe incorporation into erythrocytes, and the number of reticulocytes that were similar to increases caused by infusions of 28 milliunits of human growth hormone per day. Body weight gain and 59Fe incorporation were linearly correlated. Like growth hormone, IGF-I also caused a significant rise in serum erythropoietin concentrations. However, the stimulatory effect on erythropoiesis occurred before serum erythropoietin levels had risen. These results demonstrate that IGF-I mediates the stimulatory effect of growth hormone on erythropoiesis in vivo and thus further support the somatomedin concept. They also show that IGF-I can stimulate erythropoiesis in an endocrine manner, and they suggest two possible routes of action: a direct one and an indirect one by means of enhanced erythropoietin production.
Estimating the properties of single positive air streamers from measurable parameters
Creators: name: Bouwman, Dennis
name: Francisco, Hani
name: Ebert, Ute
Publisher: name: arXiv
Year: 2023
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: We develop an axial model for single steadily propagating positive streamers in air. It uses observable parameters to estimate quantities that are difficult to measure. More specifically, for given velocity, radius, length and applied background field, our model approximates the ionization density, the maximal electric field, the channel electric field, and the width of the charge layer. These parameters determine the primary excitations of molecules and the internal currents. Our approach is to first analytically approximate electron dynamics and electric fields in different regions of a uniformly-translating streamer head, then we match the solutions on the boundaries of the different regions to model the streamer as a whole, and we use conservation laws to determine unknown quantities. We find good agreement with numerical simulations for a range of streamer lengths and background electric fields, even if they do not propagate in a steady manner. Therefore quantities that are difficult to access experimentally can be estimated from more easily measurable quantities and our approximations. The theoretical approximations also form a stepping stone towards efficient axial multi-streamer models.
Stimulation of renin secretion by potassium-channel activation with cromakalim
Creators: name: Ferrier, C. P.
name: Kurtz, Armin
name: Lehner, P.
name: Shaw, S. G.
name: Pusterla, C.
name: Saxenhofer, H.
name: Weidmann, P.
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Adult
subject: Angiotensin II/pharmacology
subject: Benzopyrans/pharmacology
subject: Blood Pressure/drug effects
subject: Cells, Cultured
subject: Cromakalim
subject: Heart Rate/drug effects
subject: Humans
subject: Juxtaglomerular Apparatus/metabolism
subject: Male
subject: Potassium Channels/drug effects
subject: Pyrroles/pharmacology
subject: Renin/secretion
subject: Stimulation, Chemical

description: The cardiovascular and endocrine profile of cromakalim has been studied in 8 healthy men (age 25 +/- 2 years: means SEM) and its influence on renin release from cultured rat juxtaglomerular cells in vitro has also been examined. According to a double-blind, randomized sequence the subjects received placebo or cromakalim 1 mg as a single daily oral dose for 5 days. Compared to placebo, cromakalim significantly increased plasma renin activity (+ 122%; from 1.73 to 3.87 ng AI.ml-1.h-1), angiotensin II (+ 105%; from 5.1 to 10.5 pg.ml-1), and norepinephrine (+ 61%) levels, and heart rate (+ 8%). Plasma aldosterone, blood pressure and indices of the electrolyte-fluid volume state were unchanged. Cromakalim in vitro stimulated renin release, from 9.9 to 36.5 ng AI.h-1.30 min.mg cell protein, from juxtaglomerular cells. It appears that the presumed K+-channel activator cromakalim increases renin release in vivo at least in part by direct stimulation of renal juxtaglomerular cells.
Accelerating microstructure modelling via machine learning: a new method combining Autoencoder and ConvLSTM
Creators: name: Ahmad, Owais
name: Kumar, Naveen
name: Mukherjee, Rajdip
name: Bhowmick, Somnath
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Phase-field modeling is an elegant and versatile computation tool to predict microstructure evolution in materials in the mesoscale regime. However, these simulations require rigorous numerical solutions of differential equations, which are accurate but computationally expensive. To overcome this difficulty, we combine two popular machine learning techniques, autoencoder and convolutional long short-term memory (ConvLSTM), to accelerate the study of microstructural evolution without compromising the resolution of the microstructural representation. After training with phase-field generated microstructures of ten known compositions, the model can accurately predict the microstructure for the future nth frames based on previous m frames for an unknown composition. Replacing n phase-field steps with machine-learned microstructures can significantly accelerate the in silico study of microstructure evolution.
Non-Nehari manifold method for asymptotically periodic Schrödinger equation
Creators: name: Tang, Xianhua
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35J20, 35J60

description: We consider the semilinear Schrödinger equation $$ \left\{ \begin{array}{ll} -\triangle u+V(x)u=f(x, u), \ \ \ \ x\in {\R}^{N}, u\in H^{1}({\R}^{N}), \end{array} \right. $$ where $f$ is a superlinear, subcritical nonlinearity. We mainly study the case where $V(x)=V_0(x)+V_1(x)$, $V_0\in C(\mathbb{R}^N)$, $V_0(x)$ is 1-periodic in each of $x_1, x_2, \ldots, x_N$ and $\sup[σ(-\triangle +V_0)\cap (-\infty, 0)]<0
description: 19 pages,0 figures, SCIENCE CHINA Mathematics 2014
The Origin and Universality of the Stellar Initial Mass Function
Creators: name: Offner, Stella S. R.
name: Clark, Paul C.
name: Hennebelle, Patrick
name: Bastian, Nathan
name: Bate, Matthew R.
name: Hopkins, Philip F.
name: Moraux, Estelle
name: Whitworth, Anthony P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We review current theories for the origin of the Stellar Initial Mass Function (IMF) with particular focus on the extent to which the IMF can be considered universal across various environments. To place the issue in an observational context, we summarize the techniques used to determine the IMF for different stellar populations, the uncertainties affecting the results, and the evidence for systematic departures from universality under extreme circumstances. We next consider theories for the formation of prestellar cores by turbulent fragmentation and the possible impact of various thermal, hydrodynamic and magneto-hydrodynamic instabilities. We address the conversion of prestellar cores into stars and evaluate the roles played by different processes: competitive accretion, dynamical fragmentation, ejection and starvation, filament fragmentation and filamentary accretion flows, disk formation and fragmentation, critical scales imposed by thermodynamics, and magnetic braking. We present explanations for the characteristic shapes of the Present-Day Prestellar Core Mass Function and the IMF and consider what significance can be attached to their apparent similarity. Substantial computational advances have occurred in recent years, and we review the numerical simulations that have been performed to predict the IMF directly and discuss the influence of dynamics, time-dependent phenomena, and initial conditions.
description: 24 pages, 6 figures. Accepted for publication as a chapter in Protostars and Planets VI, University of Arizona Press (2014), eds. H. Beuther, R. S. Klessen, C. P. Dullemond, Th. Henning
Non-Abelian Gauge Symmetry and the Higgs Mechanism in F-theory
Creators: name: Grassi, Antonella
name: Halverson, James
name: Shaneson, Julius L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Algebraic Geometry (math.AG)
subject: Geometric Topology (math.GT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Singular fiber resolution does not describe the spontaneous breaking of gauge symmetry in F-theory, as the corresponding branch of the moduli space does not exist in the theory. Accordingly, even non-abelian gauge theories have not been fully understood in global F-theory compactifications. We present a systematic discussion of using singularity deformation, which does describe the spontaneous breaking of gauge symmetry in F-theory, to study non-abelian gauge symmetry. Since this branch of the moduli space also exists in the defining M-theory compactification, it provides the only known description of gauge theory states which exists in both pictures; they are string junctions in F-theory. We discuss how global deformations give rise to local deformations, and also give examples where local deformation can be utilized even in models where a global deformation does not exist. Utilizing deformations, we study a number of new examples, including non-perturbative descriptions of $SU(3)$ and $SU(2)$ gauge theories on seven-branes which do not admit a weakly coupled type IIb description. It may be of phenomenological interest that these non-perturbative descriptions do not exist for higher rank $SU(N)$ theories.
description: 30 pages. v2: Updated codes, added references, and discussed how local deformation can be utilized even when a global deformation does not exist (the case of non-Higgsable clusters). v3: final version, published in Communications in Mathematical Physics
Matched filter optimization of kSZ measurements with a reconstructed cosmological flow field
Creators: name: Li, Ming
name: Angulo, Raul E.
name: White, Simon D. M.
name: Jasche, Jens
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We develop and test a new statistical method to measure the kinematic Sunyaev-Zel'dovich (kSZ) effect. A sample of independently detected clusters is combined with the cosmic flow field predicted from a galaxy redshift survey in order to derive a matched filter that optimally weights the kSZ signal for the sample as a whole given the noise involved in the problem. We apply this formalism to realistic mock microwave skies based on cosmological $N$-body simulations, and demonstrate its robustness and performance. In particular, we carefully assess the various sources of uncertainty, cosmic microwave background primary fluctuations, instrumental noise, uncertainties in the determination of the velocity field, and effects introduced by miscentring of clusters and by uncertainties of the mass-observable relation (normalization and scatter). We show that available data (\plk\ maps and the MaxBCG catalogue) should deliver a $7.7σ$ detection of the kSZ. A similar cluster catalogue with broader sky coverage should increase the detection significance to $\sim 13σ$. We point out that such measurements could be binned in order to study the properties of the cosmic gas and velocity fields, or combined into a single measurement to constrain cosmological parameters or deviations of the law of gravity from General Relativity.
description: 17 pages, 10 figures, 3 tables. Submitted to MNRAS. Comments are welcomed
Rate of erythropoietin formation in humans in response to acute hypobaric hypoxia
Creators: name: Eckardt, Kai-Uwe
name: Boutellier, U.
name: Kurtz, Armin
name: Schopen, M.
name: Koller, E. A.
name: Bauer, Christian
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Adult
subject: Anoxia/metabolism
subject: Atmospheric Pressure
subject: Erythropoietin/biosynthesis
subject: Humans
subject: Male
subject: Radioimmunoassay

description: This study was carried out to investigate the early changes in erythropoietin (EPO) formation in humans in response to hypoxia. Six volunteers were exposed to simulated altitudes of 3,000 and 4,000 m in a decompression chamber for 5.5 h. EPO was measured by radioimmunoassay in serum samples withdrawn every 30 min during altitude exposure and also in two subjects after termination of hypoxia (4,000 m). EPO levels during hypoxia were significantly elevated after 114 and 84 min (3,000 and 4,000 m), rising thereafter continuously for the period investigated. Mean values increased from 16.0 to 22.5 mU/ml (3,000 m) and from 16.7 to 28.0 mU/ml (4,000 m). This rise in EPO levels corresponds to 1.8-fold (3,000 m) and 3.0-fold (4,000 m) increases in the calculated production rate of the hormone. After termination of hypoxia, EPO levels continued to rise for approximately 1.5 h and after 3 h declined exponentially with an average half-life time of 5.2 h.
title: Παράγοντες που επηρεάζουν την ικανοποίηση των πελατών στην ηλεκτρονική εξυπηρέτηση των ελληνικών τραπεζών
title: Factors affecting customer satisfaction in the e-service of Greek banks
Creators: name: Κουκιανακη Χαραυγη
Publisher: name: Technical University of Crete
Year: 2022

description: Στο πρώτο κεφάλαιο προσεγγίζονται οι βασικές έννοιες της τραπεζικής. Βασικές έννοιες όπως του πιστωτικού ιδρύματος, της τράπεζας και των ειδών των τραπεζών, της τραπεζικής γενικότερα, του πελάτη και της ικανοποίησης του, εισάγονται σ’ αυτή την ενότητα.
Στο δεύτερο κεφάλαιο συνεχίζεται το χτίσιμο του θεωρητικού υπόβαθρου της εργασίας με την προσέγγιση της ηλεκτρονικής εξυπηρέτησης των πελατών των τραπεζών. Αρχικά αναφέρεται η εξέλιξη της ηλεκτρονικής τραπεζικής στην Ελλάδα και στην συνέχεια παρατίθενται οφέλη και τα μειονεκτήματα της. Το κεφάλαιο ολοκληρώνεται με συζήτηση πάνω στις υπηρεσίες ηλεκτρονικής τραπεζικής.
Το τρίτο κεφάλαιο περιλαμβάνει την ανάλυση της ερευνητικής μεθοδολογίας. Σε πρώτο επίπεδο γίνεται αναφορά στη ερευνητική προσέγγιση, τα μοντέλα εκτίμησης της ικανοποίησης και γενικότερα το θεωρητικό υπόβαθρο για να τεθεί και ο σκοπός της παρούσας έρευνας. Η ενότητα ολοκληρώνεται με μια σύντομη περιγραφή της μεθοδολογίας MUSA, που επιλέγεται ως εργαλείο για επεξεργασία των δεδομένων που συλλέχτηκαν από την έρευνα και εξαγωγή συμπερασμάτων.
Στο τέταρτο κεφάλαιο παρουσιάζεται το δείγμα της έρευνας για την παρούσα μεταπτυχιακή εργασία. Δημογραφικά και άλλα στοιχεία, όπως οι προτιμώμενες από τους ερωτηθέντες υπηρεσίες και μέσα διεκπεραίωσης τους, παρατίθενται εδώ, εξάγοντας το γενικότερο προφίλ του δείγματος.
Το πέμπτο κεφάλαιο παρουσιάζει διεξοδικά τα αποτελέσματα της έρευνας με βάση την μεθοδολογία ανάλυσης MUSA. Αρχικά παρουσιάζεται και αναλύεται η συνολική ικανοποίηση των πολιτών/χρηστών της ηλεκτρονικής τραπεζικής στην Ελλάδα. Στην συνέχεια παρουσιάζεται η ικανοποίηση των πελατών ανά κριτήριο (Ευχρηστία, Ασφάλεια και ιδιωτικότητα, Ανταπόκριση – Διεπικοινωνία, Αξιοπιστία), καθώς και για κάθε ένα από τα υποκριτήρια του εκάστοτε κριτηρίου. Έπειτα παρουσιάζονται τα βάρη και μέσοι δείκτες ικανοποίησης των κριτηρίων. Ακολουθούν τα διαγράμματα με την σειρά που εξάγονται από την μεθοδολογία, δηλαδή:
a. Διαγράμματα Απαιτητικότητας – Αποτελεσματικότητας
b. Διαγράμματα δράσης
c. Διαγράμματα βελτίωσης
Η ενότητα ολοκληρώνεται με την εκτίμηση προχωρημένων αποτελεσμάτων:
a. Ανάλυση Μεταβελτιστοποίησης
b. Συναρτήσεις Μερικής Ικανοποίησης
c. Ανάλυση Ευστάθειας
d. Πίνακας Πρόβλεψης
Στην ενότητα που ακολουθεί εκθέτονται αναλυτικά τα πολύ χρήσιμα συμπεράσματα τα οποία εξάγονται από την εκπόνηση της παρούσας έρευνας και της μελέτης των αποτελεσμάτων.
Τέλος στην έβδομη ενότητα καταθέτονται προβληματισμοί και σενάρια πιθανών μελλοντικών επεκτάσεων της παρούσας εργασίας, έτσι όπως προκύπτουν αμοιβαία από την διαδικασία που ακολουθήθηκε και τα συμπεράσματα που εξήχθησαν.