cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Application and comparison of dynamic routing models for unsteady flow in simple and compound channels.
Creators: name: Chatila, Jean George.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Engineering, Civil.

description: The present research investigates the numerical modelling aspects of unsteady flow in compound channels, with special interest in the "flood plain conveyance" aspects. This is examined through applications of three unsteady flow dynamic routing models: DWOPER, EXTRAN, and ONE-D to both laboratory and field data sets. In the context of applying DWOPER to the data sets three different approaches to define "off-channel" storage areas were considered. The first, which viewed the composite flow field as a single hydraulic unit without storage, produced significant differences between simulated and observed stage and discharge hydrographs. The second and third options separated the shallow and deep zones of the compound flow fields using different types of (imaginary) interface planes. The second option, which considered vertical interface planes, gave generally good results for the laboratory data but was less successful when applied to the field data. The third option used diagonal interface planes to define flood plain storage areas. The inclination of the diagonal plane to the horizontal ($\Theta$) was adjusted to reflect changing hydraulic conditions. The form of the simulated hydrographs using this particular approach was found to be sensitive to variations in $\Theta$. Statistical analyses were performed to determine optimum $\Theta$-values for a wide range of hydraulic conditions. Finally, an equation was developed to define the flood plain hydraulic boundaries.
Fractal analyses and geometrical models of fracture surfaces in rock.
Creators: name: Roach, Daniel Edward.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Geology.

description: Fracture propagation in rock often produces complex patterns, such as the branching patterns of fracture networks, or the irregular radiating patterns on fracture surfaces. These patterns often appear complex because they are unpredictable in detail, yet predictable in the sense that smaller pieces of the pattern, when suitably enlarged, are statistically similar to larger pieces of the pattern. This property of statistical self-similarity can be quantified using fractal geometry. The fractal nature of rock fracture patterns is related to lithological properties and to the dynamics of the fracturing processes. Joint surfaces in homogeneous rocks display rough radiating ridges. A "plumose joint" surface was analyzed using the slit island method and found to have a fractal dimension (D$\sb{\rm f}$) of 2.24 $\pm$.14 (95%). Surfaces with similar fractal dimensions (2.2-2.5) are produced by a three-dimensional computer simulation of jointing. In the simulation, randomly-distributed defects cause local mis-orientations of the stress field and local deflection of the propagating fracture front. After passing through the defect the joint surface is re-oriented relative to remote stresses, and a planar radial fracture segment (i.e. inclusion hackle) is formed. Collectively, the numerous inclusion hackle form the plumose surface pattern. For the simulation results, D$\sb{\rm f}$ increases (i.e. the surface gets rougher) in proportion to the log of the defect density. The simulation also demonstrates a complex relationship between D$\sb{\rm f}$ of the propagating fracture front and D$\sb{\rm f}$ of the fracture surface. Shatter cones are conical fracture surfaces produced during high energy events such as meteorite impact and nuclear explosion. These fractures also display radiating surface features. Using a modified version of the slit island method, the fractal dimension of a shatter cone surface in limestone is estimated to be 2.24 $\pm$ 0.09. The observation of shingled convex fracture surfaces within the conical envelope surrounding the shatter cone surface is demonstrated to support the genetic model of Johnson and Talbot (1964). Striations on these fracture surfaces are reinterpreted as micro-fracture intersections. The measured fractal dimensions of the joint and shatter cone surfaces (i.e 2.24) are within the range reported for most fracture surfaces in metals (i.e. 2.1 $\sim$ 2.3).
title: Moral Panic of Islamist Extremism: Elite-Engineered fear harming the Hierarchy of Credibility
Creators: name: French, P
Publisher: name: Liverpool John Moores University
Year: 2024

description: Moral panics can lead to substantial changes in a society, but their framework should be re-evaluated in light of the effects of modern communication technology. This study focused on the moral panic surrounding Islamist extremism, including its impact on the Hierarchy of Credibility, the dominance of Western elites in shaping public opinion, and the role of new communication technologies such as the Internet and social media. The study also examined the influence of disinformation on social trustworthiness and the function of elite figures in framing social issues, contributing to mass fear and negative portrayals. The research aimed to enhance academic understanding of moral panic theory by examining the impact of technological advancements on moral panic framework and the roles of social actors, with the goal of modernizing the field. It is crucial for researchers to consider the influence of new communication technologies and address the lack of extensive research on moral panic in the context of terrorism and conspiracy theories. The study used a non-experimental, interpretative case study design, collecting news headlines from Lexis Library, Google search engine, and Facebook, and analysing approximately 2,477 of them thematically. Additionally, approximately 2,500 Facebook comments from 13 selected news articles published in 2016 were collected to examine discourse and frames presented by elite social figures. The research uncovered multiple themes, both quantitative and qualitative, with quantitative data showing that news coverage of terrorism surpassed that of other potentially more hazardous events. This coverage reached its peak in 2017, following a series of Islamist-inspired terrorist attacks in the UK. The study's results indicate that Western elites must be mindful of how sensitive issues are distorted and how this impacts their reputational legitimacy and the trustworthiness of the information they disseminate. Furthermore, the study emphasizes the significance of considering conspiracy theories and the role disinformation plays in shaping public opinion. The analysis of Facebook comments revealed a broad range of concerns, including widespread fear, a deep mistrust of government and news media, and support for extreme solutions. The implications of this study emphasize the relevance of moral panic theory in contemporary society. The research findings illustrate the applicability of moral panic to Islamist terrorism and how elite-driven panics can affect the public's beliefs, resulting in the proliferation of conspiracy theories and the erosion of traditional power structures.
Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus
Creators: name: Duncan, Maggie C.
name: Onguéné, Pascal Amoa
name: Kihara, Ibuki
name: Nebangwa, Derrick N.
name: Naidu, Maya E.
name: Williams, David E.
name: Balgi, Aruna D.
name: Andrae-Marobela, Kerstin
name: Roberge, Michel
name: Andersen, Raymond J.
name: Niikura, Masahiro
name: Ntie-Kang, Fidele
name: Tietjen, Ian
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2020

description: The increasing prevalence of drug-resistant influenza viruses emphasizes the need for new antiviral countermeasures. The M2 protein of influenza A is a proton-gated, proton-selective ion channel, which is essential for influenza replication and an established antiviral target. However, all currently circulating influenza A virus strains are now resistant to licensed M2-targeting adamantane drugs, primarily due to the widespread prevalence of an M2 variant encoding a serine to asparagine 31 mutation (S31N). To identify new chemical leads that may target M2(S31N), we performed a virtual screen of molecules from two natural product libraries and identified chebulagic acid as a candidate M2(S31N) inhibitor and influenza antiviral. Chebulagic acid selectively restores growth of M2(S31N)-expressing yeast. Molecular modeling also suggests that chebulagic acid hydrolysis fragments preferentially interact with the highly-conserved histidine residue within the pore of M2(S31N) but not adamantane-sensitive M2(S31). In contrast, chebulagic acid inhibits in vitro influenza A replication regardless of M2 sequence, suggesting that it also acts on other influenza targets. Taken together, results implicate chebulagic acid and/or its hydrolysis fragments as new chemical leads for M2(S31N) and influenza-directed antiviral development.
Supplementary document for Nicotinamide effects on metabolism of human fibroblasts and keratinocytes assessed by quantitative, label-free fluorescence imaging - 5369079.pdf
Creators: name: liu, Zhiyi
name: Chiang, Chung-Yi
name: Nip, John
name: Feng, Lin
name: Zhang, Yang
name: Rocha, Sheila
name: Georgakoudi, Irene
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental materials
exoALMA IV: Substructures, Asymmetries, and the Faint Outer Disk in Continuum Emission
Creators: name: Curone, Pietro
name: Facchini, Stefano
name: Andrews, Sean M.
name: Testi, Leonardo
name: Benisty, Myriam
name: Czekala, Ian
name: Huang, Jane
name: Ilee, John D.
name: Isella, Andrea
name: Lodato, Giuseppe
name: Loomis, Ryan A.
name: Stadler, Jochen
name: Winter, Andrew J.
name: Bae, Jaehan
name: Barraza-Alfaro, Marcelo
name: Cataldi, Gianni
name: Cuello, Nicolás
name: Fasano, Daniele
name: Flock, Mario
name: Fukagawa, Misato
name: Galloway-Sprietsma, Maria
name: Garg, Himanshi
name: Hall, Cassandra
name: Izquierdo, Andrés F.
name: Kanagawa, Kazuhiro
name: Lesur, Geoffroy
name: Longarini, Cristiano
name: Menard, Francois
name: Orihara, Ryuta
name: Pinte, Christophe
name: Price, Daniel J.
name: Rosotti, Giovanni
name: Teague, Richard
name: Wafflard-Fernandez, Gaylor
name: Wilner, David J.
name: Wölfer, Lisa
name: Yen, Hsi-Wei
name: Yoshida, Tomohiro C.
name: Zawadzki, Brianna
Publisher: name: arXiv
Year: 2025
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The exoALMA Large Program targeted a sample of 15 disks to study gas dynamics within these systems, and these observations simultaneously produced continuum data at 0.9 mm (331.6 GHz) with exceptional surface brightness sensitivity at high angular resolution. To provide a robust characterization of the observed substructures, we performed a visibility space analysis of the continuum emission from the exoALMA data, characterizing axisymmetric substructures and nonaxisymmetric residuals obtained by subtracting an axisymmetric model from the observed data. We defined a nonaxisymmetry index and found that the most asymmetric disks predominantly show an inner cavity and consistently present higher values of mass accretion rate and near-infrared excess. This suggests a connection between outer disk dust substructures and inner disk properties. The depth of the data allowed us to describe the azimuthally averaged continuum emission in the outer disk, revealing that larger disks (both in dust and gas) in our sample tend to be gradually tapered compared to the sharper outer edge of more compact sources. Additionally, the data quality revealed peculiar features in various sources, such as shadows, inner disk offsets, tentative external substructures, and a possible dust cavity wall.
description: This paper is part of the exoALMA Focus Issue of The Astrophysical Journal Letters
title: Heat and health in the WHO European Region: updated evidence for effective prevention
title: Heat and health in the WHO European Region: updated evidence for effective prevention
titleType: AlternativeTitle
Creators: name: Bjerglund Andersen, Nina
name: Böckmann, Melanie
name: Bowen, Kathryn
name: Mücke, Hans-Guido
Publisher: name: WHO
Year: 2021
Subjects: Städtebau
Klimaänderung
Volksgesundheit
Risikomanagement
Europa

description: The WHO Regional Office for Europe published guidance on heat-health action planning in 2008, and intends to update this to include the latest evidence. An in-depth review was initiated, based on recent epidemiological and environmental research and lessons learned from implementation in practice. This publication collates and summarizes the most relevant evidence published since 2008, focusing primarily on Member States in the WHO European Region. Findings are organized around the elements the original guidance document identified as "core" to a comprehensive heat-health action plan (HHAP), and these are complemented in each chapter with the results of a WHO survey of heat-health action planning in 2019, where relevant to the topic covered. Despite the existing gaps in knowledge, the evidence presented clearly points to a need to expand the number, coverage and reach of HHAPs in the Region. The updated guidance will be beneficial to support enhanced HHAP implementation. © World Health Organization
Interactive multimedia and problem based learning: experiencing project failure
Creators: name: Nulden, Urban
name: Scheepers, Helana
Publisher: name: Swinburne
Year: 2024

description: In this paper we discuss research on computer support for experiential learning and problem based learning (PBL). Experiential learning combined with interactive multimedia has received a great deal of attention in both educational practice and research. We suggest that the advancement of multimedia technology also provides an opportunity to extend problem based learning and combine it with experiential learning. We have focused on the very early phase of PBL, often called the “vignette.” The vignette is used by the teacher to present a problematic situation that should serve as stimulus for a self-directed learning process. We have surveyed experienced PBL students and teachers with the purpose of finding ideas on how the vignette can be enriched or transformed by interactive multimedia. The analysis of the survey then served as input for the design of an interactive multimedia vignette prototype. The prototype was evaluated in two different settings: university and industry. Our conclusion is that the prototype works as a tool to integrate experiential learning and problem based learning. We found that the interactive multimedia added important dimensions to the first phase of the PBL model. We end the paper with a systematization of the results from the evaluation into a methodology, PIE, for integrating problem based learning, interactive multimedia and experiential learning. A more extensive evaluation of the prototype and the methodology will be reported at a later date.
A Comprehensive Review on Mucoadhesive Drug Delivery System
Creators: name: Patil HD
name: Jain AS
name: Patil DR
name: Shaikh AZ
name: Shaikh SR
name: Dr. Pawar SP
Publisher: name: Zenodo
Year: 2024

description: Since the eyes are protected by a special architecture and physiology, the transport of medications administered using conventional dosage forms is restricted to the eye, and therapeutic drug concentrations in the target tissues are not sustained for an extended period of time. Various droppable items to extend the retention duration on the ocular surface have been introduced to the market for the treatment of the anterior portion of the eye. For the treatment of chronic vitreoretinal disorders, direct intravitreal implants made of biodegradable or non-biodegradable polymers have been extensively studied. The treatment of chronic diseases urgently requires the development of ocular drug delivery systems that offer controlled release and promote patient and physician convenience while lowering the frequency of dosage and intrusive treatment. This article reviews the development of ocular medication delivery systems that are now through clinical trials and late stages of experimentation.

Keywords: Anatomy and physiology of eye, cornea, contact lens, barriers of ocular drug delivery, drug delivery system for anterior and posterior segment of eye, implants, liposomes, Microemulsion
Dealing with Wastewater and Water Purification from the Age of Early Modernity to the Present: An Inquiry Into the Management of the Ottawa River
Creators: name: Murray, Matthew
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Ottawa River
City of Ottawa
Wastewater
Wastewater Treatment
Water Purification
Water Treatment
Management of the Ottawa River
Normal Accident Theory
Risk Management
Early Modernity

description: This thesis examines the impact of urban water infrastructure on the Ottawa River through an exploration of the City of Ottawa's historical development from the early modern period to the present. The primary aim is to explain how the Ottawa River came to be removed or ignored from the City of Ottawa's urban development strategy. The thesis focuses on the periods of 1910-1920 (early modernity) and 1999-2012 (present). The theories applied are risk, risk management, normal accident theory and the politics of infrastructure. The data and information for this thesis were primarily retrieved from the City of Ottawa website as well as from the archives of the City of Ottawa. The thesis identifies several factors explaining why the Ottawa River has been mistreated over time, as well as the challenges involved in reforming present-day practices and infrastructure. Several recommendations to fix the situation are advanced.
An Improved N2 Model for Predicting Gas Adsorption in MOFs and using Molecular Simulation to aid in the Interpretation of SSNMR Spectra of MOFs
Creators: name: Provost, Bianca
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: MOF
Nitrogen
Molecular simulation
Solid-state NMR
Parameterization
Carbon capture

description: Microporous metal organic frameworks (MOFs) are a novel class of materials formed through self-assembly of inorganic and organic structural building units (SBUs). They show great promise for many applications thanks to record-breaking internal surface areas, high porosity as well as a wide variety of possible chemical compositions. Molecular simulation has been instrumental in the study of MOFs to date, and this thesis work aims to validate and expand upon these efforts through two distinct computational MOF investigations. Current separation technologies used for CO2/N2 mixtures, found in the greenhouse gas-emitting flue gas generated by coal-burning power plants, could greatly benefit from the improved cost-effective separation MOF technology offers. MOFs have shown great potential for CO2 capture due to their low heat capacities and high, selective uptake of CO2. To ensure that simulation techniques effectively predict quantitative MOF gas uptakes and selectivities, it is important that the simulation parameters used, such as force fields, are adequate. We show that in all cases explored, the force field in current widespread use for N2 adsorption over-predicts uptake by at least 50% of the experimental uptake in MOFs. We propose a new N2 model, NIMF (Nitrogen in MoFs), that has been parameterized using experimental N2 uptake data in a diverse range of MOFs found in literature. The NIMF force field yields high accuracy N2 uptakes and will allow for accurate simulated uptakes and selectivities in existing and hypothetical MOF materials and will facilitate accurate identification of promising materials for CO2 capture and storage as well as air separation for oxy-fuel combustion. We also present the results of grand canonical and canonical Monte Carlo (GCMC and canonical MC), DFT and molecular dynamics (MD) simulations as well as charge density analyses, on both CO2 and N,N-dimethylformamide adsorbed in Ba2TMA(NO3) and MIL-68(In), two MOFs with non-equivalent inorganic structural building units. We demonstrate the excellent agreement found between our simulation results and the solid-state NMR (SSNMR) experiments carried out by Professor Yining Huang (Western University) on these two MOFs. Molecular simulation enables discoveries which complement SSNMR such as the number, distribution and dynamics of guest binding sites within a MOF. We show that the combination of SSNMR and molecular simulation forms a powerful analytical procedure for characterizing MOFs, and this novel set of microscopic characterization techniques allows for the optimization of new and existing MOFs.
The composition and capacity of the clinical genetics workforce in high-income countries : A scoping review
Creators: name: Dragojlovic, Nick
name: Borle, Kennedy
name: Kopac, Nicola
name: Ellis, Ursula
name: Birch, Patricia
name: Adam, Shelin
name: Friedman, J. M. (Jan Marshall), 1947-
name: Nisselle, Amy
name: Elliott, Alison M.
name: Lynd, Larry D.
Publisher: name: Springer Nature
Year: 2021

description: As genetics becomes increasingly integrated into all areas of healthcare and the use of complex genetic tests continues to grow, the clinical genetics workforce will likely face greatly increased demand for its services. To inform strategic planning by healthcare systems to prepare to meet this future demand, we performed a scoping review of the genetics workforce in high-income countries, summarizing all available evidence on its composition and capacity published between 2010 and 2019. Five databases (MEDLINE, Embase, PAIS, CINAHL, and Web of Science) and grey literature sources were searched, resulting in 162 unique studies being included in the review. The evidence presented includes the composition and size of the workforce, the scope of practice for genetics and non-genetics specialists, the time required to perform genetics-related tasks, caseloads of genetics providers, and opportunities to increase efficiency and capacity. Our results indicate that there is currently a shortage of genetics providers and that there is a lack of consensus about the appropriate boundaries between the scopes of practice for genetics and non-genetics providers. Moreover, the results point to strategies that may be used to increase productivity and efficiency, including alternative service delivery models, streamlining processes, and the automation of tasks.
A Study to Assess the Effectiveness of Lamaze Breathing Technique in Pain Management During the First Stage of Labour in Apollo Women's Hospital, Chennai
Creators: name: Latha A.R.
name: Divya B R
name: Roopali W.
Publisher: name: gjrpublication
Year: 2024

description: Introduction: Labor pain is a physiological phenomenon caused by the smooth muscles of the uterus contracting to assist the fetus down the birth canal. There are many causes of this pain, such as experience, fear and anxiety along with racial, cultural, social, and environmental factors and demographic and biological characteristics. Severe labor anxiety increases the likelihood of a cesarean section, which may be followed by cesarean delivery-related difficulties for both mother and fetus, putting financial strains on the family and the state and lengthening hospitalization time. Problem Statement: A study to assess the effectiveness of Lamaze breathing technique in pain management during the first stage of labour in Apollo Women’s Hospital, Chennai. Objectives: (a) To assess the pre and post test level of pain scores among mothers who are in the first stage of labour. (b) To evaluate the effectiveness of Lamaze breathing on the level of pain among mothers before and after who are in labour. (c) To associate the selected demographic variables with the mean differed score of pain among all mothers who are in labour. Methodology: Quantitative research approach with one group pre and post test design was adopted. The samples for this study consist of 30 samples selected by purposive sampling technique. Wong Bakers Pain scale was used to assess the pain level among mothers in the first stage of labour. Results: The pretest mean score of pain level among primigravida mothers was 6.6 and post test mean score of pain level among primigravida mothers was 1.57. The paired‘t’ value of the group was 14.631. Conclusion: The study shows that the Lamaze breathing technique is effective in reducing the level of pain.
Comparative judgment and proof comprehension: supplementary material
Creators: name: Davies, Benjamin
name: Alcock, Lara
name: Jones, Ian
Publisher: name: Loughborough University
Year: 2020
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences

description: Supplementary materials for 2016 research on proof summaries, comparative judgement and proof comprehension.
This folder contains two files. The first file includes transcriptions of students' summaries of a proof demonstrating the uncountability of the open unit interval. The other file contains three quantitative measures associated with our proof summaries research. Comparative judgment-based parameter estimates for students' proof summaries, alongside final course scores and scores on the multiple-choice comprehension test from Mejia-Ramos et al. (2017).
Bullying and Peer Victimization of Ethnic Majority and Minority Youth: Meta-Analyses and School Context
Creators: name: Vitoroulis, Irene
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Ethnicity
Meta-analysis
Bullying
School ethnic composition
Peer victimization

description: The study of ethnicity in bullying research has yielded inconsistent findings regarding the involvement and prevalence rates among ethnic majority and minority groups. On one hand, individual studies using ethnic group membership as a demographic variable indicate that ethnic minority groups are at times more or less likely to experience or perpetrate bullying compared to White students. On the other hand, contextual factors such as ethnic diversity have yielded more consistent findings showing that increased ethnic diversity is associated with lower bullying victimization among ethnic minority students. The role of ethnicity in bullying and peer victimization was examined in this dissertation by investigating both individual and contextual variables. Studies 1 and 2 consisted of two meta-analyses that systematically addressed comparisons between ethnic majority (i.e., White) and minority students (i.e., Black, Asian, Hispanic) on bullying perpetration and peer victimization. Results indicated small and non-significant overall effect sizes; however, methodological moderators suggested that ethnic groups differ on bullying and peer victimization across countries, measurements, and age groups. Study 3 examined school ethnic composition and bullying involvement in a population-based, ethnically diverse Canadian sample. Results indicated that ethnic minority students experienced less bullying victimization in schools with a higher proportion of ethnic minority peers. School ethnic composition was not associated with bullying victimization for White students or bullying perpetration across both ethnic groups. Taken together, these studies suggest that ethnicity as a demographic variable is not sufficient to account for differences in bullying involvement and that contextual variables are more adequate at explaining patterns of bullying across ethnic groups within the larger school and societal contexts.
Exploring dispersion dynamics in agitated mixers via numerical simulations and machine learning
Creators: name: Liang, Fuyue
Publisher: name: Imperial College London
Year: 2024

description: This thesis employs three-dimensional simulations combined with a hybrid front-tracking/level-set method to elucidate the complex interplay between flow dynamics and interfacial behaviours in a practical operational unit. Specifically, it examines the mixing of immiscible oil and water by a pitched blade turbine in a cylindrical vessel. The study focuses on the effects of impeller rotation frequency, the presence of surface active agents (surfactants) and their physiochemical properties on the evolution of interface and mixing performance, including interfacial area, dispersed drop number, and drop size distribution within the system. Furthermore, due to the high computational cost of high-fidelity simulations, several data-driven models based on recurrent neural network are constructed using the simulation data and evaluated as an alternative approach for predicting dispersion performance metrics over multiple future time-steps based on their initial observations. The results from this thesis provide a detailed picture of the underlying physics and interfacial dynamics within mixing systems as influenced by impeller speed, surfactant elasticity and solubility. This work bridges the gap in understanding of liquid-liquid dispersion process. Moreover, this thesis examines the applicability of several popular machine learning techniques in the field of multiphase flow mixing, highlighting the challenges and critical considerations involved in this process.
exoALMA XII: Weighing and sizing exoALMA disks with rotation curve modelling
Creators: name: Longarini, Cristiano
name: Lodato, Giuseppe
name: Rosotti, Giovanni
name: Andrews, Sean
name: Winter, Andrew
name: Stadler, Jochen
name: Izquierdo, Andrés
name: Galloway-Spriestma, Maria
name: Facchini, Stefano
name: Curone, Pietro
name: Benisty, Myriam
name: Teague, Richard
name: Bae, Jaehan
name: Barraza-Alfaro, Marcelo
name: Cataldi, Gianni
name: Czekala, Ian
name: Cuello, Nicolás
name: Fasano, Daniele
name: Flock, Mario
name: Fukakgwa, Misato
name: Garg, Himanshi
name: Hall, Cassandra
name: Hammond, Iain
name: Hardiman, Caitlyn
name: Hilder, Thomas
name: Huang, Jane
name: Ilee, John
name: Isella, Andrea
name: Kanagawa, Kazuhiro
name: Lesur, Geoffroy
name: Loomis, Ryan A.
name: Ménard, François
name: Orihara, Ryuta
name: Pinte, Christophe
name: Price, Daniel J.
name: Testi, Leonardo
name: Wafflard-Fernandez, Gaylor
name: Wölfer, Lisa
name: Yen, Hsi-Wei
name: Yoshida, Tomohiro C.
name: Zawadzki, Brianna
Publisher: name: arXiv
Year: 2025
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The exoALMA large program offers a unique opportunity to investigate the fundamental properties of protoplanetary disks, such as their masses and sizes, providing important insights in the mechanism responsible for the transport of angular momentum. In this work, we model the rotation curves of CO isotopologues $^{12}$CO and $^{13}$CO of ten sources within the exoALMA sample, and we constrain the stellar mass, the disk mass and the density scale radius through precise characterization of the pressure gradient and disk self gravity. We obtain dynamical disk masses for our sample measuring the self-gravitating contribution to the gravitational potential. We are able to parametrically describe their surface density, and all of them appear gravitationally stable. By combining dynamical disk masses with dust continuum emission data, we determine an averaged gas-to-dust ratio of approximately 400, not statistically consistent with the standard value of 100, assuming optically thin dust emission. In addition, the measurement of the dynamical scale radius allows for direct comparison with flux-based radii of gas and dust. This comparison suggests that substructures may influence the size of the dust disk, and that CO depletion might reconcile our measurements with thermochemical models. Finally, with the stellar mass, disk mass, scale radius, and accretion rate, and assuming self-similar evolution of the surface density, we constrain the effective $α_S$ for these systems. We find a broad range of $α_S$ values ranging between $10^{-5}$ and $10^{-2}$.
description: This paper is part of the exoALMA Focus Issue of The Astrophysical Journal Letters
Calcium Dynamics of Isolated Goldfish (Carassius auratus) Retinal Horizontal Cells: Effects of Oxygen-Glucose Deprivation
Creators: name: Campbell, Benjamin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Hypoxia
Goldfish
Horizontal Cell
Retina
Ischemia
Oxygen-Glucose Deprivation
Calcium
Microspectrofluorometry

description: Studies on the survival of central nervous system of hypoxia-tolerant species under challenges of reduced energy availability have characterised adaptive mechanisms of brain at the cell and tissue level that lead to reduced excitability and protection. However, evidence of hypoxic suppression of retinal activity in these species has not been followed up with mechanistic studies. Microspectrofluorometric monitoring of intracellular free Ca2+ concentration ([Ca2+]i) is useful for identifying cellular mechanisms that may lead to adaptive strategies, as unregulated increases in [Ca2+]i cause toxicity. Horizontal cells (HCs) are second order retinal neurons that receive tonic excitatory input from photoreceptors, and possess voltage-gated Ca2+ conductances and other channels that can facilitate toxic increases in [Ca2+]i under conditions of reduced energy availability (modeled as oxygen-glucose deprivation, OGD). It was demonstrated that isolated HCs of the hypoxia-tolerant goldfish display spontaneous, transient [Ca2+]i activity (SA) which decreased in amplitude and area under the curve following OGD or glucose removal (20 min) without recovery. SA was shown to be dependent on extracellular Ca2+ influx through voltage-gated Ca2+ channels, though mechanisms of SA generation and regulation has yet to be determined. Additionally, glutamate-elicited peak increases in [Ca2+]i were reduced after 20 min of OGD. The removal of O2 during OGD insult seemed to be protective as an increase in baseline [Ca2+]i was seen during and following glucose removal under normoxic conditions. The mechanisms mediating these decreases in spontaneous and elicited [Ca2+]i activity are currently unknown, though candidate pathways are discussed. This thesis contributes a hint towards how HCs may tolerate conditions of low energy availability, which may also inform investigations on their role in situ during these insults.
Progression ou régression dans les hautes sphères de la direction : qu'en est-il de la perception des femmes cadres des entreprises publiques?
Creators: name: Bastien, Christine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Femmes cadres
Perception
Obstacles et facteurs de réussite
Relations intergroupes
Changement

description: Pour cette thèse de recherche, nous nous sommes intéressées à la perception des femmes gestionnaires des entreprises publiques dans le secteur des communications, quant à leurs conditions de travail, notamment les obstacles et les facteurs de réussite rencontrés au cours de leur progression de carrière. Au Québec et ailleurs en occident, les mouvements féministes ont lutté pour que les femmes soient reconnues au même titre que les hommes et aient les mêmes droits face à l’État. Ainsi les femmes ont eu accès, entres autres, à la contraception et aux études supérieures. Ces pionnières sont donc entrées dans des milieux traditionnellement masculins, un changement qui provoqua plusieurs réactions négatives de la part des partisans et partisanes du statu quo. Ces femmes se retrouvaient en minorité, notamment dans les hautes sphères de la gestion, niveau cadre. Aujourd’hui, les femmes cadres sont toujours en minorité, une bonne vingtaine d’années après que les premières femmes soient entrées à ces niveaux. Dans ce contexte, il est plausible de penser, avec les théories de l’identité sociale et du changement, que les femmes cadres font face à différents obstacles lors de leur progression de carrière, de même que certains facteurs favorisant leur réussite dans l’ascension de la hiérarchie. Ainsi, cette thèse aborde un sujet dans la continuité des recherches féministes qui semblent de plus en plus oubliées, alors que l’égalité entre les hommes et les femmes n’est pas atteinte. Les résultats obtenus entendent garder vivant le sujet des femmes comme groupe minoritaire, pour ne pas oublier que les obstacles qu’elles rencontrent sont bien réels mais plus sournois qu’auparavant. Quant aux facteurs de réussite, les résultats obtenus sont encourageants et apportent de l’espoir, toujours pour la quête de l’égalité entre les hommes et les femmes, ici, en milieu de travail.
L’agentivité et la naissance de la femme-sujet dans la littérature algérienne contemporaine
Creators: name: Van Deventer, Rachel
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010

description: Cette étude élargit le champ de la recherche sur l’écriture féminine algérienne contemporaine au moyen de la théorie de l’agentivité révisée au contact d’un corpus polymorphologique composé d’essais, de recueils de nouvelles et de romans. Si les études sur la francophonie et les littératures francophones ont suscité récemment un intérêt croissant, il n’existait guère jusqu’à aujourd’hui d’étude d’une ampleur significative sur les stratégies employées par les écrivaines algériennes depuis les premiers écrits d’Assia Djebar jusqu’aux récits récents de Nina Bouraoui. L’objectif principal de cette thèse est de mettre au grand jour les stratégies que Djebar, Sebbar, Bey et Bouraoui déploient pour positionner la femme comme agent et sujet de son discours. En outre, l’étude cherche à cerner la manière dont elles se démarquent à l’intérieur du champ littéraire algérien. Pour ce faire, l’approche agentiviste proposée par Havercroft a été revisitée. Alors que Havercroft propose une analyse à deux volets (l’agentivité extratextuelle et intratextuelle), cette étude s’appuie sur une approche à quatre volets permettant de mieux examiner la relation étroite entre les écrivaines, le milieu socioculturel et le champ littéraire. Les quatre volets consistent en une étude de l’agentivité extratextuelle, transtextuelle, interdiscursive et intratextuelle. Le premier volet traite des conditions de publication, des effets de la publication, et du lien entre le vécu, l’autobiographie et le texte. Le deuxième volet, dans une optique genettienne, examine les occurrences textuelles telles que le paratexte, l’architexte et l’intertexte. Le rôle de l’Histoire/histoire et le reversement des discours dominants, notamment la subversion du discours colonial contemporain et la remise en question du discours patriarcal, font l’objet d’un troisième volet. Enfin, le dernier volet met en relief des choix thématiques, l’onomastique des personnages féminins, le choix de vocabulaire et la voix narrative. L’analyse textuelle renforce l’aspect théorique de la thèse en ce qui concerne la constitution d’un sous-champ littéraire algérien au féminin. En tenant compte des théories de Bourdieu quant à la capacité des agents sociaux à avoir un impact sur la production culturelle ainsi qu’à sa définition du concept de l’habitus, et de celles d’Isabelle Boisclair (2004) sur le processus constitutif d’un sous-champ au féminin, il est possible de proposer l’existence d’un sous-champ algérien au féminin. Cette thèse ouvre ainsi une nouvelle perspective sur l’histoire littéraire algérienne contemporaine. D’une part, elle montre que la naissance de la femme-sujet a eu lieu bien avant l’Indépendance algérienne et, d’autre part, elle définit les paramètres perméables et changeants dans lesquels s’épanouit la femme algérienne agente.
World Food Atlas Project
Creators: name: Rostami, Ali
name: Xie, Z
name: Ishino, A
name: Yamakata, Y
name: Aizawa, K
name: Jain, Ramesh
Publisher: name: arXiv
Year: 2025
Subjects: subject: Information Retrieval (cs.IR)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: A coronavirus pandemic is forcing people to be "at home" all over the world. In a life of hardly ever going out, we would have realized how the food we eat affects our bodies. What can we do to know our food more and control it better? To give us a clue, we are trying to build a World Food Atlas (WFA) that collects all the knowledge about food in the world. In this paper, we present two of our trials. The first is the Food Knowledge Graph (FKG), which is a graphical representation of knowledge about food and ingredient relationships derived from recipes and food nutrition data. The second is the FoodLog Athl and the RecipeLog that are applications for collecting people's detailed records about food habit. We also discuss several problems that we try to solve to build the WFA by integrating these two ideas.
Digitale Techniken und Green Economy
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2022
Subjects: Nachhaltigkeit
Grüne Wirtschaft

description: Fragen der Green Economy werden bislang weitgehend getrennt von der Digitalisierung betrachtet. Im Forschungsbericht wurden die Transformationspotenziale von Big Data, Künstlicher Intelligenz (KI) und digitalen Plattformen auf dem Weg zu einer Green Economy in den Blick genommen. Dabei wurden sowohl die privatwirtschaftliche als auch staatliche Anwendung betrachtet. Auf Basis der gewonnenen Erkenntnisse werden Handlungsempfehlungen für umwelt-, klima- und nachhaltigkeitsbezogene Veränderungen der rechtlichen und regulatorischen Rahmenbedingungen entwickelt. Quelle: www.umweltbundesamt.de
Study of the Factors Affecting the Selectivity of Catalytic Ethylene Oligomerization
Creators: name: Albahily, Khalid
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Chromium
Ethylene Oligomerization
Trimerization
Alpha Olefins

description: Over the past decade, advances in ethylene oligomerization have witnessed explosive growth of interest from both commercial and academic standpoint, with chromium metal invariably being the metal of preference. A common feature in this literature was the extended long debate regarding the mechanism, metal oxidation states responsible for selectivity and the role of the ligand. This thesis work embarked on the isolation and characterization of new active intermediates called “single component catalysts” (or self activating) to address two important questions: (1) how the catalyst precursors re-arrange upon activation and (2) the real oxidation state of the activated species. Four different ligands systems have been examined for this purpose. The first part is a study on the NPIIIN ligand which can be described as a dynamic and non-spectator ligand. Upon aluminum alkyl activation, a series of single component chromium catalysts for selective ethylene oligomerization and polymerization have been isolated, fully characterized and tested. New selective single component chromium(I) catalysts have also been isolated and tested positively for ethylene trimerization. The second part includes a new series of chromium complexes based on the NPVN ligand. This ligands enabled to obtain the first polymer-free extremely active catalytic system. In both NPN ligand systems, a new activation pathway was discovered by using vinyl Grignard reagent [(CH2=CH)MgCl] as activator and/or reducing agent. The third part explores new modified pyrrole-chromium complexes which were found to be highly active and selective ethylene trimerization catalysts. This part was a continuation of previous work from our lab to complete the mechanistic picture of this highly successful pyrrole-chromium catalyst independently commercialized by Phillips-Chevron and Mitsubishi. Interestingly upon aluminum alkyl treatment, the first example of a Schrock-type chromium ethylidene complex has been isolated and characterized and found to be a potent catalyst for selective ethylene trimerization. Finally, the other ligands introduced in this thesis are new systems called pyridine-SNS and Si-SNS that introduce some modification to the known commercial SNS catalyst (Sasol technology). The introduction of a pyridine ring or a silyl unit in the ligand scaffold has allowed to understand the mechanism of action of this remarkable system.
Meta-Analysis : Exposure to Early Life Stress and Risk for Depression in Childhood and Adolescence
Creators: name: LeMoult, Joelle
name: Humphreys, Kathryn L.
name: Tracy, Alison
name: Hoffmeister, Jennifer-Ashley
name: Ip, Eunice
name: Gotlib, Ian H.
Publisher: name: Elsevier
Year: 2022

description: Objective: Early life stress (ELS) is associated with increased risk for the development of major depressive disorder (MDD) in adulthood; the degree to which ELS is associated with an early onset of MDD (i.e., during childhood or adolescence), however, is not known. In this meta-analysis, we estimated the associations between ELS and the risk for onset of MDD before age 18 years. In addition, we examined the associations between eight specific forms of ELS (i.e., sexual abuse, physical abuse, poverty, physical illness/injury, death of a family member, domestic violence, natural disaster, and emotional abuse) and risk for youth-onset MDD. Method: We conducted a systematic search in scientific databases for studies that assessed both ELS and the presence or absence of MDD before age 18 years. We identified 62 journal articles with a total of 44,066 unique participants. We assessed study quality using the Newcastle-Ottawa Scale. When heterogeneous effect sizes were detected, we tested whether demographic and/or methodological factors moderated the association between ELS and MDD. Results: Using a random-effects meta-analysis, we found that individuals who experienced ELS were more likely to develop MDD before the age of 18 than were individuals without a history of ELS (OR=2.50; 95% CI [2.08, 3.00]). Separate meta-analyses revealed a range of associations with MDD; while some types of ELS (e.g., poverty) were not associated with MDD, other types (e.g., emotional abuse) were associated more strongly with MDD than was ELS considered more broadly. Conclusion: These findings provide important evidence that the adverse effect of ELS on MDD risk manifests early in development, prior to adulthood, and varies by type of ELS.