cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cultivation-dependent and cultivation-independent characterization of hydrocarbon-degrading bacteria in Guaymas Basin sediments
Creators: name: Aitken, Michael D.
name: Teske, Andreas
name: Gutierrez, Tony
name: Biddle, Jennifer F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Marine hydrocarbon-degrading bacteria perform a fundamental role in the biodegradation of crude oil and its petrochemical derivatives in coastal and open ocean environments. However, there is a paucity of knowledge on the diversity and function of these organisms in deep-sea sediment. Here we used stable-isotope probing (SIP), a valuable tool to link the phylogeny and function of targeted microbial groups, to investigate polycyclic aromatic hydrocarbon (PAH)-degrading bacteria under aerobic conditions in sediments from Guaymas Basin with uniformly labeled [13C]-phenanthrene (PHE). The dominant sequences in clone libraries constructed from 13C-enriched bacterial DNA (from PHE enrichments) were identified to belong to the genus Cycloclasticus. We used quantitative PCR primers targeting the 16S rRNA gene of the SIP-identified Cycloclasticus to determine their abundance in sediment incubations amended with unlabeled PHE and showed substantial increases in gene abundance during the experiments. We also isolated a strain, BG-2, representing the SIP-identified Cycloclasticus sequence (99.9% 16S rRNA gene sequence identity), and used this strain to provide direct evidence of PHE degradation and mineralization. In addition, we isolated Halomonas, Thalassospira, and Lutibacterium sp. with demonstrable PHE-degrading capacity from Guaymas Basin sediment. This study demonstrates the value of coupling SIP with cultivation methods to identify and expand on the known diversity of PAH-degrading bacteria in the deep-sea.
title: Schultoiletten als diskriminierungsfreie Räume gestalten
Creators: name: Schwaderer, Carla
Publisher: name: DuEPublico
Year: 2022

description: blog interdisziplinäre geschlechterforschung
description: Schultoiletten sind politische Räume, die hart umkämpft werden. Einerseits kann hier Unzufriedenheit und Wut durch Vandalismus zum Ausdruck gebracht werden und andererseits dienen sie als Rückzugsraum, weil sie die einzige Möglichkeit in einem Schulgebäude bieten, legitimiert allein und unbeobachtet zu sein. Sie können diskriminierend sein, indem durch binäre Geschlechtertrennung bzw. durch nicht gegebene Barrierefreiheit bestimmte Personengruppen benachteiligt oder sogar ausgeschlossen werden. Wird diese Binarität aber aufgebrochen, können sie zu einem Diskurs über Genderaspekte anregen. Sie können Geschlechterrollen reproduzieren und gleichzeitig hinterfragen und die Schüler*innen zum Nachdenken über bestehende Diskriminierungsformen anregen. Die Berücksichtigung all dieser Aspekte bei der räumlichen Positionierung und Ausgestaltung dieser Räume sollte an Bedeutsamkeit gewinnen.
Schreibkompetenz thailändischer Studierender mit Deutsch als Nebenfach am Beispiel von narrativen Texten unter dem Aspekt der Textkohärenz
Creators: name: Supatcha Jennasombut
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2021
Subjects: Schreibkompetenz
Textkohärez
Narrativer Text

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 21, 2, 472-499
การให้เหตุผลสนับสนุนความรู้ที่มาจากวิกิพีเดีย: มุมมองญาณวิทยาว่าด้วยคำบอกเล่าของประจักษ์พยาน
Creators: name: เด่นพงษ์ แสนคำ
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2021
Subjects: วิกิพีเดีย
คำบอกเล่าของประจักษ์พยาน
ความรู้
ญาณวิทยาเชิงสังคม

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 21, 2, 500-531
Linear conic optimization for inverse optimal control
Creators: name: Pauwels, Edouard
name: Henrion, Didier
name: Lasserre, Jean-Bernard
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: We address the inverse problem of Lagrangian identification based on trajecto-ries in the context of nonlinear optimal control. We propose a general formulation of the inverse problem based on occupation measures and complementarity in linear programming. The use of occupation measures in this context offers several advan-tages from the theoretical, numerical and statistical points of view. We propose an approximation procedure for which strong theoretical guarantees are available. Finally, the relevance of the method is illustrated on academic examples.
บทบาทของสถาบันคลังสมอง (Think Tank) ในการกำหนดนโยบายต่างประเทศของสหพันธรัฐรัสเซีย
Creators: name: กฤษฎา พรหมเวค
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2021
Subjects: คลังสมอง
รัสเซีย
นโยบายต่างประเทศ

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 21, 2, 532-563
Nitric oxide as a regulator of B. anthracis pathogenicity
Creators: name: Zhou, Weidong
name: Vaseghi, Haley
name: Espina, Virginia
name: Teunis, Allison
name: Popov, Serguei G.
name: Liotta, Lance A.
name: Popova, Taissia G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Nitric oxide (NO) is a key physiological regulator in eukaryotic and prokaryotic organisms. It can cause a variety of biological effects by reacting with its targets or/and indirectly inducing oxidative stress. NO can also be produced by bacteria including the pathogenic Bacillus anthracis; however, its role in the infectious process only begins to emerge. NO incapacitates macrophages by S-nitrosylating the intracellular proteins and protects B. anthracis from oxidative stress. It is also implicated in the formation of toxic peroxynitrite. In this study we further assessed the effects of B. anthracis NO produced by the NO synthase (bNOS) on bacterial metabolism and host cells in experiments with the bNOS knockout Sterne strain. The mutation abrogated accumulation of nitrite and nitrate as tracer products of NO in the culture medium and markedly attenuated growth in both aerobic and microaerobic conditions. The regulatory role of NO was also suggested by the abnormally high rate of nitrate denitrification by the mutant in the presence of oxygen. Anaerobic regulation mediated by NO was reflected in reduced fermentation of glucose by the mutant correlating with the reduced toxicity of bacteria toward host cells in culture. The toxic effect of NO required permeabilization of the target cells as well as the activity of fermentation-derived metabolite in the conditions of reduced pH. The host cells demonstrated increased phosphorylation of major survivor protein kinase AKT correlating with reduced toxicity of the mutant in comparison with Sterne. Our global proteomic analysis of lymph from the lymph nodes of infected mice harboring bacteria revealed numerous changes in the pattern and levels of proteins associated with the activity of bNOS influencing key cell physiological processes relevant to energy metabolism, growth, signal transduction, stress response, septic shock, and homeostasis. This is the first in vivo observation of the bacterial NO effect on the lymphatic system.
สถานภาพการใช้แนวคิดสัจนิยมมหัศจรรย์ (Magical Realism) ในงานวิชาการไทยรอบสองทศวรรษ (พ.ศ. 2543 - 2563)
Creators: name: อัษฎาวุธ ไชยวรรณ
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2021
Subjects: สถานภาพ
แนวคิดสัจนิยมมหัศจรรย์
สองทศวรรษ

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 21, 2, 564-590
เพลงเรื่อง เพลงแม่บทในมิติดนตรีไทย
Creators: name: ชยุติ ทัศนวงศ์วรา
Publisher: name: คณะศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์
Year: 2021
Subjects: เพลงเรื่อง
ดนตรีไทย
ทักษะดนตรี
เพลงแม่บท

description: วารสารศิลปศาสตร์ มหาวิทยาลัยธรรมศาสตร์, 21, 1, 459-475
Myxiops Zanata & Akama 2004, new genus
Creators: name: Zanata, Angela M.
name: Akama, Alberto
Publisher: name: Zenodo
Year: 2004
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Characiformes
Characidae
Myxiops

description: Myxiops, new genus Type species. Myxiops aphos, by monotypy and present designation. Diagnosis. Myxiops is a characid genus of relatively small body size (maximum known SL 56.1 mm). The following combination of derived features distinguishes Myxiops from all other characid fishes: (1) infraorbitals fused in a unique fashion, resulting in less than six autogenous bones; (2) presence of a single tooth row in the premaxilla; (3) presence of “cheirodontin-like teeth”, somewhat pedunculated, expanded and compressed distally, with cusps similar in shape and perfectly aligned along dorsal margin; (4) ventral margin of toothed portion of maxillary curved towards the ventral margin of the premaxilla and maxillary teeth forming a continuous series with premaxillary teeth; (5) margins of pre- and postzygapophyses with projections anteriorly and posteriorly directed; (6) accumulation of epithelial cells forming globular structures distributed over head and scales; and (7) base of anal-fin without scales covering basal portion of unbranched and anterior branched rays. Etymology. Myxiops from the Greek, myxa for slime, and iops for small fish, in reference to the copious amount of mucous covering the body, which makes the fish very slippery when alive and even for some period after fixation in formalin and storage in alcohol.
description: Published as part of Zanata, Angela M. & Akama, Alberto, 2004, Myxiops aphos, new characid genus and species (Characiformes: Characidae) from the rio Lençóis, Bahia, Brazil, pp. 45-54 in Neotropical Ichthyology 2 (2) on page 46, DOI: 10.1590/S1679-62252004000200001, http://zenodo.org/record/5416842
Die subfossil-feuchten Großreste aus dem spätneolithischen Fundplatz Quern-Neukirchen LA 28 (Tegelbarg), Kreis Schleswig-Flensburg
Creators: name: Schaller, Luise
name: Kirleis, Wiebke
Publisher: name: Offa
Year: 2018

description: Aus dem Bereich des Unterlaufes der Habernisser Au sind mehrere neolithische Küstensiedlungen bekannt. Die archäobotanische Analyse bezieht sich auf die Neugrabung am Fundplatz Quern-Neukirchen LA 28 (Tegelbarg) im Jahr 2011. Sie gewährt neue Einblicke in die Wirtschaftsweise und Vegetationsverhältnisse der nordischen Dolchzeit zwischen 2200 und 1950 v. Chr. (Spätneolithikum 1). Im Verlauf der Grabung wurden 40 Bodenproben gewonnen, aus denen die untersuchten Großreste stammen. Das pflanzliche Material ist bis auf eine Ausnahme im subfossil-feuchten Zustand erhalten geblieben. Der Anbau von Kulturpflanzen hat offenbar in Quern-Neukirchen keine Rolle gespielt, denn es fehlen mit einer Ausnahme Getreidefragmente. Dem ist die aus verschiedenen Pflanzengesellschaften bestehende spätneolithische Landschaft entgegenzusetzen, die vom Menschen vielfältig genutzt wurde. Die naturräumlichen Voraussetzungen entlang der Küste waren für die Nahrungsbeschaffung besonders gut geeignet. Demnach sammelte man Muscheln und Schnecken an der Küste sowie in dem unter anderem aus Erlen (Alnus glutinosa), Eschen (Fraxinus) und Linden (Tilia) bestehenden, landeinwärts gelegenen Auwald Himbeeren (Rubus idaeus), Schlehen (Prunus spinosa) und Hagebutten (Rosa). Diese Tätigkeiten verweisen auf die saisonale Nutzung des in einem natürlichen Gunstraum gelegenen Fundplatzes.
description: Offa, 71/72 (2014/2015)
The Spatial Variation of the Cooling Lines in the Reflection Nebula NGC7023
Creators: name: Bernard-Salas, J.
name: Habart, E.
name: Köhler, M.
name: Abergel, A.
name: Arab, H.
name: Lebouteiller, V.
name: Pinto, C.
name: van der Wiel, M. H. D.
name: White, G. J.
name: Hoffmann, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Context: The north-west photo-dissociation region (PDR) in the reflection nebula NGC 7023 displays a complex structure. Filament-like condensations at the edge of the cloud can be traced via the emission of the main cooling lines, offering a great opportunity to study the link between the morphology and energetics of these regions. Aims: We study the spatial variation of the far-infrared fine-structure lines of [C II] (158 um) and [O I] (63 and 145 um). These lines trace the local gas conditions across the PDR. Methods: We used observations from the Herschel/PACS instrument to map the spatial distribution of these fine-structure lines. The observed region covers a square area of about 110" x 110" with an angular resolution that varies from 4" to 11". We compared this emission with ground-based and Spitzer observations of H2 lines, Herschel/SPIRE observations of CO lines, and Spitzer/IRAC 3.6 um images that trace the emission of polycyclic aromatic hydrocarbons. Results: The [C II] (158 um) and [O I] (63 and 145 um) lines arise from the warm cloud surface where the PDR is located and the gas is warm, cooling the region. We find that although the relative contribution to the cooling budget over the observed region is dominated by [O I]63 um (>30%), H2 contributes significantly in the PDR (35%), as does [C II]158 um outside the PDR (30%). Other species contribute little to the cooling ([O I]145 um 9%, and CO 4%). The [O I] maps resolve these condensations into two structures and show that the peak of [O I] is slightly displaced from the molecular H2 emission. The size of these structures is about 8" (0.015 pc) and in surface cover about 9% of the PDR emission. Finally, we did not detect emission from [N II]122 um, suggesting that the cavity is mostly filled with non-ionised gas.
description: 10 pages, 7 figures, 1 Table
title: Deconstructing the rock anthem : textual form, participation and collectivity
Creators: name: Dockwray, Ruth.
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis focuses on the main attributes of rock anthems. It asks the questions, 'What makes a rock anthem?' and 'How may we define a rock anthem?'. Through textual analysis and paralinguistic analysis, the thesis discusses aspects of multi-modal participation, such as singing, clapping, swaying and waving that have become identifiable features of rock anthems. The musical analysis highlights common musical and lyrical attributes that prove to be conducive in creating vocal participation from audiences. The pedagogical nature of rock anthems is highlighted, through musical analysis and also through an analysis of music video. The world-wide knowledge of the accompanying rock anthem gestures is discussed with reference to the influence of video as a form of mediation in teaching audiences how and when to participate. The gestural participation that is generated in rock anthem performances is discussed in terms of its communicative role and the production of collectivity. The thesis also further explores the idea of band/audience interaction in a live context to create one performer and the notion of the rock community, with particular reference to the 1985 'Live Aid' concert. The musical and social role of rock anthems is considered in new types of anthems. The discussion of other anthems such as football and dance anthems highlights the continuity-change that has taken place, emphasising the community building feature of anthems. While new forms of anthems, as socio-musical practices have emerged, the anthem as a term is also considered. The mass mediation of 'anthem' through CD compilations and the impact media has had on the spread of the 'anthem' as a label is also discussed
Phylogeography, Salinity Adaptations and Metabolic Potential of the Candidate Division KB1 Bacteria Based on a Partial Single Cell Genome
Creators: name: Nigro, Lisa M.
name: Hyde, Andrew S.
name: Teske, Andreas
name: MacGregor, Barbara J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Deep-sea hypersaline anoxic basins (DHABs) and other hypersaline environments contain abundant and diverse microbial life that has adapted to these extreme conditions. The bacterial Candidate Division KB1 represents one of several uncultured groups that has been consistently observed in hypersaline microbial diversity studies. Here we report the phylogeography of KB1, its phylogenetic relationships to Candidate Division OP1 Bacteria, and its potential metabolic and osmotic stress adaptations based on a partial single cell amplified genome (SAG) of KB1 from Orca Basin, the largest hypersaline seafloor brine basin in the Gulf of Mexico. Our results are consistent with the hypothesis – previously developed based on 14C incorporation experiments with mixed-species enrichments from Mediterranean seafloor brines - that KB1 has adapted its proteins to elevated intracellular salinity, but at the same time KB1 apparently imports glycine betaine; this compatible solute is potentially not limited to osmoregulation but could also serve as a carbon and energy source.
Study of SU(2) gauge theories with multiple Higgs fields in different representations
Creators: name: Catumba, Guilherme
name: Hiraguchi, Atsuki
name: Hou, George W.-S.
name: Jansen, Karl
name: Kao, Ying-Jer
name: Lin, C.-J. David
name: Ramos, Alberto
name: Sarkar, Mugdha
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2022
Subjects: temperature, 0
particle, spectrum
gauge field theory, SU(2)
electroweak interaction, critical phenomena
space-time, dimension, 4
superconductivity
finite temperature
condensed matter
doublet

description: We study two different SU(2) gauge-scalar theories in 3 and 4 spacetime dimensions. Firstly, we focus on the 3 dimensional SU(2) theory with multiple Higgs fields in the adjoint representation, that can be mapped to cuprate systems in condensed matter physics which host a rich phase diagram including high-Tc superconductivity. It has been proposed that the theory with 4 adjoint Higgs fields can be used to explain the physics of hole-doped cuprates for a wide range of parameters. We show exploratory results on the phase diagram of the theory. On the other hand, we are interested in the 4 dimensional theory with 2 sets of fundamental scalar (Higgs) fields, which is relevant to the 2 Higgs Doublet Model (2HDM), a proposed extension to the Standard Model of particle physics. The goal is to understand the particle spectrum of the theory at zero temperature and the electroweak phase transition at finite temperature. We present exploratory results on scale setting and the multi-parameter phase diagram of this theory.
Pichia pastoris-expressed dengue 3 envelope-based virus-like particles elicit predominantly domain III-focused high titer neutralizing antibodies
Creators: name: Tyagi, Poornima
name: Tripathi, Lav
name: Arora, Upasana
name: Swaminathan, Sathyamangalam
name: Khanna, Navin
name: de Silva, Aravinda
name: Mani, Shailendra
name: Poddar, Ankur
name: Raut, Rajendra
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Dengue poses a serious public health risk to nearly half the global population. It causes ~400 million infections annually and is considered to be one of the fastest spreading vector-borne diseases. Four distinct serotypes of dengue viruses (DENV-1, -2, -3, and -4) cause dengue disease, which may be either mild or extremely severe. Antibody-dependent enhancement (ADE), by pre-existing cross-reactive antibodies, is considered to be the major mechanism underlying severe disease. This mandates that a preventive vaccine must confer simultaneous and durable immunity to each of the four prevalent DENV serotypes. Recently, we used Pichia pastoris, to express recombinant DENV-2 E ectodomain, and found that it assembled into virus-like particles (VLPs), in the absence of prM, implicated in the elicitation of ADE-mediating antibodies. These VLPs elicited predominantly type-specific neutralizing antibodies that conferred significant protection against lethal DENV-2 challenge, in a mouse model. The current work is an extension of this approach to develop prM-lacking DENV-3 E VLPs. Our data reveal that P. pastoris-produced DENV-3 E VLPs not only preserve the antigenic integrity of the major neutralizing epitopes, but also elicit potent DENV-3 virus-neutralizing antibodies. Further, these neutralizing antibodies appear to be exclusively directed toward domain III of the DENV-3 E VLPs. Significantly, they also lack discernible ADE potential toward heterotypic DENVs. Taken together with the high productivity of the P. pastoris expression system, this approach could potentially pave the way toward developing a DENV E-based, inexpensive, safe, and efficacious tetravalent sub-unit vaccine, for use in resource-poor dengue endemic countries.
Primer and platform effects on 16S rRNA tag sequencing
Creators: name: Fern, Alison
name: Chen, Feng
name: Tremblay, Julien
name: Dangl, Jeffery L.
name: Tringe, Susannah G.
name: Kirton, Edward S.
name: Lee, Janey
name: Woyke, Tanja
name: Singh, Kanwar
name: He, Shaomei
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Sequencing of 16S rRNA gene tags is a popular method for profiling and comparing microbial communities. The protocols and methods used, however, vary considerably with regard to amplification primers, sequencing primers, sequencing technologies; as well as quality filtering and clustering. How results are affected by these choices, and whether data produced with different protocols can be meaningfully compared, is often unknown. Here we compare results obtained using three different amplification primer sets (targeting V4, V6–V8, and V7–V8) and two sequencing technologies (454 pyrosequencing and Illumina MiSeq) using DNA from a mock community containing a known number of species as well as complex environmental samples whose PCR-independent profiles were estimated using shotgun sequencing. We find that paired-end MiSeq reads produce higher quality data and enabled the use of more aggressive quality control parameters over 454, resulting in a higher retention rate of high quality reads for downstream data analysis. While primer choice considerably influences quantitative abundance estimations, sequencing platform has relatively minor effects when matched primers are used. Beta diversity metrics are surprisingly robust to both primer and sequencing platform biases.
Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infections
Creators: name: Nair, Madhavan
name: Mondal, Debasis
name: Roy, Upal
name: Barber, Paul
name: Tse-Dinh, Yuk-Ching
name: Batrakova, Elena V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Multi-Drug Resistance Proteins (MRPs) are members of the ATP binding cassette (ABC) drug-efflux transporter superfamily. MRPs are known to regulate the efficacy of a broad range of anti-retroviral drugs (ARV) used in highly active antiretroviral therapy (HAART) and antibacterial agents used in Tuberculus Bacilli (TB) therapy. Due to their role in efflux of glutathione (GSH) conjugated drugs, MRPs can also regulate cellular oxidative stress, which may contribute to both HIV and/or TB pathogenesis. This review focuses on the characteristics, functional expression, and modulation of known members of the MRP family in HIV infected cells exposed to ARV drugs and discusses their known role in drug-inefficacy in HIV/TB-induced dysfunctions. Currently, nine members of the MRP family (MRP1-MRP9) have been identified, with MRP1 and MRP2 being the most extensively studied. Details of the other members of this family have not been known until recently, but differential expression has been documented in inflammatory tissues. Researchers have found that the distribution, function, and reactivity of members of MRP family vary in different types of lymphocytes and macrophages, and are differentially expressed at the basal and apical surfaces of both endothelial and epithelial cells. Therefore, the prime objective of this review is to delineate the role of MRP transporters in HAART and TB therapy and their potential in precipitating cellular dysfunctions manifested in these chronic infectious diseases. We also provide an overview of different available options and novel experimental strategies that are being utilized to overcome the drug resistance and disease pathogenesis mediated by these membrane transporters.
A relevância da colaboração Sul-Sul para fomentar a Ciência Aberta não comercial em Angola e Moçambique
Creators: name: Gungula, Eurico Wongo
name: Garcia, Arianna Becerril
name: Lopez, Eduardo Aguado
name: Neupane, Bhanu
Publisher: name: Zenodo
Year: 2022

description: Apresentação realizada na sessão Conferência de Encerramento da 13ª Conferência Lusófona de Ciência Aberta, formato híbrido, de 10 a 12 de outubro de 2022.
Functions of GSK-3 Signaling in Development of the Nervous System
Creators: name: Snider, William D.
name: Kim, Woo-Yang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Glycogen synthase kinase-3 (GSK-3) is central to multiple intracellular pathways including those activated by Wnt/β-catenin, Sonic Hedgehog, Notch, growth factor/RTK, and G protein-coupled receptor signals. All of these signals importantly contribute to neural development. Early attention on GSK-3 signaling in neural development centered on the regulation of neuronal polarity using in vitro paradigms. However, recent creation of appropriate genetic models has demonstrated the importance of GSK-3 to multiple aspects of neural development including neural progenitor self-renewal, neurogenesis, neuronal migration, neural differentiation, and synaptic development.
Wire Loop
Creators: name: COOLE, INDIANA JANE
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 360602
subject: Fine arts

description: Wire Loop investigates an expanded notion of choreography. From mushroom to bicycle, this research brings together two projects that consider choreography through material practice and performance. The aim is to bring disparate matter into relation, creating patterns of coordination, as well as discord and juxtaposition. The work cycles through different kinds of activity and motion, operating across various temporal rhythms and scales. Wire Loop explores how movement can be integrated within a system—how a gesture might trigger or respond to something else. This research draws on Karen Barad’s theory of agential realism and their proposition that individual entities are not separate determinately bound objects but rather entangled parts of phenomena. This informs my understanding of choreography as enacting systems of relation and connectivity.
Role of GSK3 Signaling in Neuronal Morphogenesis
Creators: name: Hur, Eun-Mi
name: Zhou, Feng-Quan
name: Snider, William D.
name: Kim, Yun Tai
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Glycogen synthase kinase 3 (GSK3) is emerging as a key regulator of several aspects of neuronal morphogenesis including neuronal polarization, axon growth, and axon branching. Multiple signaling pathways have been identified that control neuronal polarization, including PI3K, Rho-GTPases, Par3/6, TSC–mTOR, and PKA–LKB1. However, how these pathways are coordinated is not clear. As GSK3 signaling exhibits crosstalk with each of these pathways it has the potential to integrate these polarity signals in the control neuronal polarization. After neurons establish polarity, GSK3 acts as an important signaling mediator in the regulation of axon extension and axon branching by transducing upstream signaling to reorganization of the axonal cytoskeleton, especially microtubules. Here we review the roles of GSK3 signaling in neuronal morphogenesis and discuss the underlying molecular mechanisms.
MPEC 2023-U140 : 2023 UT2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 UT2

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
France Lags Behind in the Application of Memory Science in the Courtroom
Creators: name: Dodier, Olivier
name: Morlet-Rivelli, Mickaël
name: Verkampt, Fanny
Publisher: name: Zenodo
Year: 2022

description: France has a strong psychoanalytical tradition in the application of psychology, and the legal field is no exception. In this article, we discuss the consequences of the limited use in court of knowledge about memory from cognitive sciences. As illustrations, we present published data showing the limited knowledge of French expert witnesses on memory, and a brief overview of two reports highlighting the failure of expert witnesses to mobilize reliable scientific knowledge in their reports and in the courtroom. Finally, we propose recommendations for improving practices.
Neural cell adhesion molecule, NCAM, regulates thalamocortical axon pathfinding and the organization of the cortical somatosensory representation in mouse
Creators: name: Brennaman, Leann H.
name: Maness, Patricia F.
name: Palazzetti, Cecilia
name: Fairén, Alfonso
name: Enriquez-Barreto, Lilian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: To study the potential role of neural cell adhesion molecule (NCAM) in the development of thalamocortical (TC) axon topography, wild type, and NCAM null mutant mice were analyzed for NCAM expression, projection, and targeting of TC afferents within the somatosensory area of the neocortex. Here we report that NCAM and its α-2,8-linked polysialic acid (PSA) are expressed in developing TC axons during projection to the neocortex. Pathfinding of TC axons in wild type and null mutant mice was mapped using anterograde DiI labeling. At embryonic day E16.5, null mutant mice displayed misguided TC axons in the dorsal telencephalon, but not in the ventral telencephalon, an intermediate target that initially sorts TC axons toward correct neocortical areas. During the early postnatal period, rostrolateral TC axons within the internal capsule along the ventral telencephalon adopted distorted trajectories in the ventral telencephalon and failed to reach the neocortex in NCAM null mutant animals. NCAM null mutants showed abnormal segregation of layer IV barrels in a restricted portion of the somatosensory cortex. As shown by Nissl and cytochrome oxidase staining, barrels of the anterolateral barrel subfield (ALBSF) and the most distal barrels of the posteromedial barrel subfield (PMBSF) did not segregate properly in null mutant mice. These results indicate a novel role for NCAM in axonal pathfinding and topographic sorting of TC axons, which may be important for the function of specific territories of sensory representation in the somatosensory cortex.
Stellar laboratories IV. New Ga IV, Ga V, and Ga VI oscillator strengths and the gallium abundance in the hot white dwarfs G191-B2B and RE0503-289
Creators: name: Rauch, T.
name: Werner, K.
name: Quinet, P.
name: Kruk, J. W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: For the spectral analysis of high-resolution and high-signal-to-noise (S/N) spectra of hot stars, advanced non-local thermodynamic equilibrium (NLTE) model atmospheres are mandatory. These atmospheres are strongly dependent on the reliability of the atomic data that are used to calculate them. Reliable Ga IV - VI oscillator strengths are used to identify Ga lines in the spectra of the DA-type white dwarf G191-B2B and the DO-type white dwarf RE0503-289 and to determine their photospheric Ga abundances. We newly calculated Ga IV - VI oscillator strengths to consider their radiative and collisional bound-bound transitions in detail in our NLTE stellar-atmosphere models for analyzing of Ga lines exhibited in high-resolution and high-S/N UV observations of G191-B2B and RE0503-289. We unambiguously detected 20 isolated and 6 blended (with lines of other species) Ga V lines in the Far Ultraviolet Spectroscopic Explorer (FUSE) spectrum of RE0503-289. The identification of Ga IV and Ga VI lines is uncertain because they are weak and partly blended by other lines. The determined Ga abundance is 3.5 +/- 0.5 x 10**-5 (mass fraction, about 625 times solar). The Ga IV / GA V ionization equilibrium, which is a very sensitive indicator for the effective temperature, is well reproduced in RE0503-289. We identified the strongest Ga IV lines (1258.801, 1338.129 A) in the HST/STIS (Hubble Space Telescope / Space Telescope Imaging Spectrograph) spectrum of G191-B2B and measured a Ga abundance of 2.0 +/- 0.5 x 10**-6 (about 22 times solar). Reliable measurements and calculations of atomic data are a prerequisite for stellar-atmosphere modeling. Observed Ga IV - V line profiles in two white dwarf (G191-B2B and RE0503-289) ultraviolet spectra were well reproduced with our newly calculated oscillator strengths. For the first time, this allowed us to determine the photospheric Ga abundance in white dwarfs.
description: 127 pages, 6 figures
The slope conjecture for graph knots
Creators: name: Motegi, Kimihiko
name: Takata, Toshie
Publisher: name: arXiv
Year: 2015
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 57M25, 57M27

description: The slope conjecture proposed by Garoufalidis asserts that the Jones slopes given by the sequence of degrees of the colored Jones polynomials are boundary slopes. We verify the slope conjecture for graph knots, i.e. knots whose Gromov volume vanish.
description: We found a gap in the proof of Lemma 3.1 in the last version (1501.01105v2). This lemma is replaced by Proposition 3.2 in [Kalfagianni and Tran; Knot cabling and the degree of the colored Jones polynomial (1501.01574v1)]. The title of the paper is also changed
Biology of adeno-associated viral vectors in the central nervous system
Creators: name: Samulski, Richard J.
name: Asokan, Aravind
name: Murlidharan, Giridhar
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Gene therapy is a promising approach for treating a spectrum of neurological and neurodegenerative disorders by delivering corrective genes to the central nervous system (CNS). In particular, adeno-associated viruses (AAVs) have emerged as promising tools for clinical gene transfer in a broad range of genetic disorders with neurological manifestations. In the current review, we have attempted to bridge our understanding of the biology of different AAV strains with their transduction profiles, cellular tropisms, and transport mechanisms within the CNS. Continued efforts to dissect AAV-host interactions within the brain are likely to aid in the development of improved vectors for CNS-directed gene transfer applications in the clinic.
METHODOLOGICAL ASPECTS OF DEVELOPING METHODS OF INDEPENDENT EDUCATIONAL ACTIVITY OF FUTURE TEACHERS IN THE ENVIRONMENT OF DIGITAL EDUCATION
Creators: name: Mirzamakhmudova, Nilufar
name: Mirzamaxmudova, Nilufar
Publisher: name: Zenodo
Year: 2025

description: Today, educational reform has set the task of forming a creative, inquisitive teacher who thinks in a new way, can find the right path in the flow of information in the process of globalization, who is productive in information, who can use it in the education and upbringing of the younger generation, and who is able to learn professions. The importance of this work is that no matter how much pedagogical experience introduces innovations into the content of education, no matter how perfect programs, textbooks and educational standards are created, their implementation in the educational process depends on the personality and pedagogical skills of the teacher. Multimedia materials created using digital technologies have unparalleled potential in the field of education with their ability to clearly present images, create special effects for a deeper understanding of information, and provide a wide range of visual information.
Visual search behavior and performance in luggage screening: effects of time pressure, automation aid, and target expectancy
Creators: name: Rieger, Tobias
name: Heilmann, Lydia
name: Manzey, Dietrich
Publisher: name: Technische Universität Berlin
Year: 2021
Subjects: subject: 150 Psychologie
subject: time pressure
subject: visual search
subject: automation support
subject: target expectancy
subject: luggage screening

description: Visual inspection of luggage using X-ray technology at airports is a time-sensitive task that is often supported by automated systems to increase performance and reduce workload. The present study evaluated how time pressure and automation support influence visual search behavior and performance in a simulated luggage screening task. Moreover, we also investigated how target expectancy (i.e., targets appearing in a target-often location or not) influenced performance and visual search behavior. We used a paradigm where participants used the mouse to uncover a portion of the screen which allowed us to track how much of the stimulus participants uncovered prior to their decision. Participants were randomly assigned to either a high (5-s time per trial) or a low (10-s time per trial) time-pressure condition. In half of the trials, participants were supported by an automated diagnostic aid (85% reliability) in deciding whether a threat item was present. Moreover, within each half, in target-present trials, targets appeared in a predictable location (i.e., 70% of targets appeared in the same quadrant of the image) to investigate effects of target expectancy. The results revealed better detection performance with low time pressure and faster response times with high time pressure. There was an overall negative effect of automation support because the automation was only moderately reliable. Participants also uncovered a smaller amount of the stimulus under high time pressure in target-absent trials. Target expectancy of target location improved accuracy, speed, and the amount of uncovered space needed for the search. Significance Statement Luggage screening is a safety–critical real-world visual search task which often has to be done under time pressure. The present research found that time pressure compromises performance and increases the risk to miss critical items even with automation support. Moreover, even highly reliable automated support may not improve performance if it does not exceed the manual capabilities of the human screener. Lastly, the present research also showed that heuristic search strategies (e.g., areas where targets appear more often) seem to guide attention also in luggage screening.
Understanding the impact of time pressure and automation support in a visual search task
Creators: name: Rieger, Tobias
name: Manzey, Dietrich
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 300 Sozialwissenschaften
subject: human-automation interaction
subject: visual search
subject: decision making
subject: trust in automation
subject: compliance and reliance
subject: stress

description: Objective: To understand the impact of time pressure and automated decision support systems (DSS) in a simulated medical visual search task. Background: Time pressure usually impairs manual performance in visual search tasks, but DSS support might neutralize this negative effect. Moreover, understanding the impact of time pressure and DSS support seems relevant for many real-world applications of visual search. Method: We used a visual search paradigm where participants had to search for target letters in a simulated medical image. Participants performed the task either manually or with support of a highly reliable DSS. Time pressure was varied within-subjects by either a trialwise time–pressure manipulation (Experiment 1) or a blockwise manipulation (Experiment 2). Performance was assessed based on signal detection measures. To further analyze visual search behavior, a mouse-over approach was used. Results: In both experiments, results showed impaired sensitivity under high compared to low time pressure in the manual condition, but no negative effect of time pressure when working with a highly reliable DSS. Moreover, participants searched less under time pressure and when receiving DSS support, indicating participants followed the automation without thoroughly checking recommendations. However, the human-DSS team’s sensitivity was always worse than that of the DSS alone, independent of the strength of time pressure. Conclusion: Negative effects of time pressure can be ameliorated when receiving support by a DSS, but joint overall performance remains below DSS-alone performance. Application: Highly reliable DSS seem capable of ameliorating the negative impact of time pressure in complex detection tasks.
Universal electric current of interacting resonant-level models with asymmetric interactions: An extension of the Landauer formula
Creators: name: Nishino, Akinori
name: Hatano, Naomichi
name: Ordonez, Gonzalo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the electron transport in open quantum-dot systems described by the interacting resonant-level models with Coulomb interactions. We consider the situation in which the quantum dot is connected to the left and right leads asymmetrically. We exactly construct many-electron scattering eigenstates for the two-lead system, where two-body bound states appear as a consequence of one-body resonances and the Coulomb interactions. By using an extension of the Landauer formula, we calculate the average electric current for the system under bias voltages in the first order of the interaction parameters. Through a renormalization-group technique, we arrive at the universal electric current, where we observe the suppression of the electric current for large bias voltages, i.e., negative differential conductance. We find that the suppressed electric current is restored by the asymmetry of the system parameters.
description: 27 pages, 3 figures
A Resilient Quantum Secret Sharing Scheme
Creators: name: Maitra, Arpita
name: Paul, Goutam
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Cryptography and Security (cs.CR)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: A resilient secret sharing scheme is supposed to generate the secret correctly even after some shares are damaged. In this paper, we show how quantum error correcting codes can be exploited to design a resilient quantum secret sharing scheme, where a quantum state is shared among more than one parties.
description: 12 pages, 2 figures
The coconut rhinoceros beetle (Oryctes rhinoceros) outbreak is well established on Efate, Vanuatu
Creators: name: Paudel, Sulav
name: Jackson, Trevor
name: Boulekouran, Sylvie
name: Tasale, Jeffline
name: Garae, Bill
name: Allanson, Patricia
name: Ero, Mark
name: Marshall, Sean
Publisher: name: AgResearch
Year: 2023
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences

description: The presence of coconut rhinoceros beetle (CRB: Oryctes rhinoceros) was reported on Efate, Vanuatu in 2019. The beetle population was determined to belong to the CRB-S group (Clade II), similar to populations found in the Bismark Archipelago, Papua New Guinea. An introduction of the CRB-G group (Clade IA) was discovered in 2021. Damage mapping, beetle trapping and genomic identification show that CRB-S has now spread around about half of the island from the site of the original introduction. CRB-G is mainly restricted to the seaport and surrounding areas of Port Vila with some outlying specimens. Through the efforts of Biosecurity Vanuatu, O. rhinoceros is still contained on the Efate group of islands and has not spread to the major copra-producing islands in other parts of the country. Sanitation efforts appear to have reduced damage from coconut rhinoceros beetle within the zone of first arrival of the pest (Mangaliliu, Efate). Oryctes rhinoceros damage, however, is severe in areas with old plantations and limited sanitation activities (e.g. Mele/Devil's point, Efate). A concerted effort is necessary to contain the beetle on Efate and to reduce further spread and impact on the island.
title: Female Leadership in the workforce - what do successful women in the industry have in common to reach higher management positions in a male-dominated environment.
Creators: name: Agin, Athena
Publisher: name: TU Wien
Year: 2022
Subjects: subject: female leadership
subject: upper management
subject: gender segregation

description: A lot has been done to reach gender balance at upper management levels, but the topic of femaleleadership has not lost its topicality. This leads to the assumption that the underlying problem still is not fully understood. On the other hand, it is evident that a few women successfully navigate in an upward direction within the male-dominated industry environment. Hence it is necessary to participate in the knowledge of these women and benefit from it to foster diversityand management that represents their customer base and therefore administers and manages inalignment with their customer needs.This study aims to clarify the picture of the underlying root cause that slows down the genderbalancing activities promoted by organizations and national legislation—investigating data onthe careers of successful female managers and revealing the common success strategies and the hindering factors.A quantitative approach within in-depth literature research was conducted to answer these questions.Concrete peer-reviewed papers in the scope of this thesis were undertaken by quantitative inductive content analysis to Mayring.Regarding the findings of this thesis, career-promoting factors common for successful women within the industry were Mentors, Network, Flexibility, and Support. As typical career inhibiting factors Organizational Structures, the Self, and Social Structures were identified. Further,the underlying root cause of slowing down the gender balancing activities was identified as gendered organizational structures.Further research regarding horizontal gender segregation could give further scientific insight with the potential to make further questioning of vertical gender segregation within the workforce unnecessary and even provide answers to the contradiction of gender-equal societies with evident gender-segregating structures.