title: ÐÐ»Ð¸ÑÐ½Ð¸Ðµ ÑÐ³Ð»ÐµÑÐ¾Ð´Ð½ÑÑ Ð½Ð°Ð½Ð¾ÑÑÑÐ±Ð¾Ðº Ð½Ð° Ð¿ÑÐ¾ÑÐµÑÑ ÑÐ»ÐµÐºÑÑÐ¾ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð° Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ½ÑÑ Ð¼Ð°ÑÑÐ¸Ñ Ð´Ð»Ñ ÑÐºÐ°Ð½ÐµÐ²Ð¾Ð¹ Ð¸Ð½Ð¶ÐµÐ½ÐµÑÐ¸Ð¸
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐ°ÑÑÐµÐ½Ð¸ÑÐµÐ², ÐÑÐµÐ²Ð¾Ð»Ð¾Ð´
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÐÐ¾Ð»Ð¸Ð¸Ð¼Ð¸Ð´Ñ
ÐÐ°Ð½Ð¾ÑÑÑÑÐºÑÑÑÐ½ÑÐµ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ
ÐÐ¾Ð»Ð¸Ð¼ÐµÑÑ
Ð£Ð³Ð»ÐµÑÐ¾Ð´
Ð°Ð»Ð¸ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð°Ð¼Ð¸Ð´Ñ
Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ½ÑÐµ Ð¼Ð°ÑÑÐ¸ÑÑ
ÑÐºÐ°Ð½ÐµÐ²Ð°Ñ Ð¸Ð½Ð¶ÐµÐ½ÐµÑÐ¸Ñ
aliphatic copolyamide
polymer matrix
tissue engineering

description: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ ÑÐ¿Ð¾ÑÐ¾Ð±Ñ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾ÑÐ¸ÑÑÑÑ Ð¿Ð»ÐµÐ½Ð¾ÑÐ½ÑÑ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð¾Ð² Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÐºÐ¾Ð¼Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð½Ð°Ð½Ð¾Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½ Ð¸Ð· Ð°Ð»Ð¸ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð°Ð¼Ð¸Ð´Ð° (Ð¡ÐÐ) - ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ° Îµ-ÐºÐ°Ð¿ÑÐ¾Ð»Ð°ÐºÑÐ°Ð¼Ð° Ð¸ ÑÐ¾Ð»Ð¸ Ð°Ð´Ð¸Ð¿Ð¸Ð½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ Ñ Ð´Ð¾Ð±Ð°Ð²ÐºÐ¾Ð¹ Ð¾Ð´Ð½Ð¾ÑÑÐµÐ½Ð½ÑÑ ÑÐ³Ð»ÐµÑÐ¾Ð´Ð½ÑÑ Ð½Ð°Ð½Ð¾ÑÑÑÐ±Ð¾Ðº (ÐÐ£ÐÐ¢), Ð° ÑÐ°ÐºÐ¶Ðµ Ð½Ð°Ð½Ð¾Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½ Ð¸Ð· Ð¿Ð¾Ð»Ð¸Ð°Ð¼Ð¸Ð´Ð¾ÐºÐ¸ÑÐ»Ð¾ÑÑ (ÐÐÐ) Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð´Ð¸Ð°Ð½Ð³Ð¸Ð´ÑÐ¸Ð´Ð° 3,3', 4,4'- Ð´Ð¸ÑÐµÐ½Ð¸Ð» ÑÐµÑÑÐ°ÐºÐ°ÑÐ±Ð¾Ð½Ð¾Ð²Ð¾Ð¹ ÐºÐ¸ÑÐ»Ð¾ÑÑ Ð¸ Ð¾-ÑÐ¾Ð»Ð¸Ð´Ð¸Ð½Ð°. ÐÐµÑÐ¾Ð´Ð¾Ð¼ ÑÐµÑÐ¼Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÐºÐ»Ð¸Ð·Ð°ÑÐ¸ÐµÐ¹ Ð½Ð°Ð½Ð¾Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½ Ð¸Ð· ÐÐÐ Ð¿Ð¾Ð»ÑÑÐµÐ½Ñ Ð²Ð¾Ð»Ð¾ÐºÐ½Ð° Ð¸Ð· Ð°ÑÐ¾Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð¾Ð»Ð¸Ð¸Ð¼Ð¸Ð´Ð° (ÐÐ). ÐÐ¾ÐºÐ°Ð·Ð°Ð½Ð¾, ÑÑÐ¾ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð°Ñ Ð²ÑÐ·ÐºÐ¾ÑÑÑ ÑÐ°ÑÑÐ²Ð¾ÑÐ¾Ð² Ð¡ÐÐ Ð² ÑÐ¿Ð¸ÑÑÐ¾Ð²Ð¾Ð´Ð½Ð¾Ð¼ ÑÐ°ÑÑÐ²Ð¾ÑÐ¸ÑÐµÐ»Ðµ, ÑÐ¾Ð´ÐµÑÐ¶Ð°ÑÐ¸Ñ ÐÐ£ÐÐ¢, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°ÑÑÐ²Ð¾ÑÐ¾Ð² ÐÐÐ Ð² ÑÐ¼ÐµÑÐ¸ Ð°Ð¿ÑÐ¾ÑÐ¾Ð½Ð½ÑÑ Ð¸ Ð±ÐµÐ½Ð·Ð¾Ð¸Ð´Ð½ÑÑ ÑÐ°ÑÑÐ²Ð¾ÑÐ¸ÑÐµÐ»ÐµÐ¹ Ð·Ð°Ð²Ð¸ÑÐ¸Ñ Ð¾Ñ ÑÐºÐ¾ÑÐ¾ÑÑÐ¸ ÑÐ´Ð²Ð¸Ð³Ð°. ÐÑÐ±ÑÐ°Ð½Ñ Ð¾Ð¿ÑÐ¸Ð¼Ð°Ð»ÑÐ½ÑÐµ ÐºÐ¾Ð½ÑÐµÐ½ÑÑÐ°ÑÐ¸Ð¸ ÑÐ°ÑÑÐ²Ð¾ÑÐ¾Ð² Ð¸ ÑÐ¾Ð´ÐµÑÐ¶Ð°Ð½Ð¸Ðµ Ð½Ð°Ð½Ð¾ÑÐ°ÑÑÐ¸Ñ, Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑÐ¸Ðµ Ð¿Ð¾Ð»ÑÑÐ°ÑÑ Ð½Ð°Ð½Ð¾Ð²Ð¾Ð»Ð¾ÐºÐ½Ð° Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼ ÑÐ»ÐµÐºÑÑÐ¾ÑÐ¾ÑÐ¼Ð¾Ð²Ð°Ð½Ð¸Ñ. ÐÐ»ÐµÐ½Ð¾ÑÐ½ÑÐµ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÐºÐ¾Ð¼Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð½Ð°Ð½Ð¾Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½ Ð¸Ð· Ð¡ÐÐ Ð¸ ÐÐ£ÐÐ¢ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸Ð·ÑÑÑÑÑ Ð´Ð¸Ð°Ð¼ÐµÑÑÐ¾Ð¼ Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½ 100-400 Ð½Ð¼, Ð¼Ð¾Ð´ÑÐ»ÐµÐ¼ ÑÐ¿ÑÑÐ³Ð¾ÑÑÐ¸ Ð=85,71Â±9,03 ÐÐÐ°, Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÑÑ Ï¬=8,09Â±1,32 ÐÐÐ°, ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÐ° Ð½Ð°ÑÐ°Ð»Ð° ÑÐµÑÐ¼Ð¾Ð´ÐµÑÑÑÑÐºÑÐ¸Ð¸ Ð¢=173,3Â°Ð¡. ÐÐ°ÑÐµÑÐ¸Ð°Ð»Ñ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð½Ð°Ð½Ð¾Ð²Ð¾Ð»Ð¾ÐºÐ¾Ð½ Ð¸Ð· ÐÐ Ð¸Ð¼ÐµÑÑ Ð´Ð¸Ð°Ð¼ÐµÑÑ 100-300 Ð½Ð¼, Ð=71,5Â±8,34, Ï¬=7,03Â±0,89, ÑÐµÐ¼Ð¿ÐµÑÐ°ÑÑÑÑ Ð½Ð°ÑÐ°Ð»Ð° ÑÐµÑÐ¼Ð¾Ð´ÐµÑÑÑÑÐºÑÐ¸Ð¸ Ð¢=537Â°Ð¡. ÐÐµÑÐ¾Ð´Ð¾Ð¼ ÐÐ¢Ð¢ (Ð¾ÑÐµÐ½ÐºÐ° Ð¼Ð¸ÑÐ¾ÑÐ¾Ð½Ð´ÑÐ¸Ð°Ð»ÑÐ½Ð¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÐºÐ»ÐµÑÐ¾Ðº Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ Ð±ÑÐ¾Ð¼Ð¸Ð´Ð° 3-(4,5-Ð´Ð¸Ð¼ÐµÑÐ¸Ð»ÑÐ¸Ð°Ð·Ð¾Ð»-2-Ð¸Ð»)-2,5-Ð´Ð¸ÑÐµÐ½Ð¸Ð»ÑÐµÑÑÐ°Ð·Ð¾Ð»Ð¸Ñ) Ð¿Ð¾ÐºÐ°Ð·Ð°Ð½Ð¾ Ð¾ÑÑÑÑÑÑÐ²Ð¸Ðµ ÑÐ¸ÑÐ¾ÑÐ¾ÐºÑÐ¸ÑÐ½Ð¾ÑÑÐ¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½ÑÑ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð¾Ð². ÐÐ»ÐµÑÐºÐ¸, ÐºÑÐ»ÑÑÐ¸Ð²Ð¸ÑÑÐµÐ¼ÑÐµ Ð½Ð° Ð½Ð¸Ñ, Ð¾Ð±Ð»Ð°Ð´Ð°ÑÑ Ð²ÑÑÐ¾ÐºÐ¾Ð¹ Ð¿ÑÐ¾Ð»Ð¸ÑÐµÑÐ°ÑÐ¸Ð²Ð½Ð¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑÑ.
description: The purpose of the work is to process biocompatible nanofibers by electrospinning from synthetic polymers. These polymers are: 1) aliphatic copolyamide (CoPa) as a copolymer of Îµ-caprolactam and salt of adipic acid with or without single-walled carbon nanotubes (SWCNT); 2) aromatic polyamic acid (PAA), prepared from 3,3', 4,4'-biphenyl tetracarboxylic acid and o-tolidine) and 3) an aromatic polyimide (PI) obtained by thermal cyclization of PAA. It was shown that the effective viscosity of the solutions CoPA/SWCNT depended on the shear rate. The similar dependence for PAA solutions in a mixture of aprotic and benzenoid solvents was obtained. The optimal parameters for electrospinning of solutions were chosen. Film materials based on CoPA/SWCNT composite nanofibers with diameter 100-400 nm have Young modulus E = 85.71Â±9.03 MPa, tensile strength Ï¬=8.09Â±1.32 MPa, initiation temperature of thermal decomposition is 173.3Â°C. The films based on PI nanofibers with diameter of 100-300 nm have E=71.5Â±8.34 MPa, Ï¬=7.03Â±0.89 MPa, initiation temperature of thermal decomposition was 537Â°C. Lack of cytotoxicity of processed materials was shown by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) method. The cells cultured on such films are characterized by a good proliferative activity.