cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Clinical Versus Rapid Molecular HIV Diagnosis in Hospitalized African Infants: A Randomized Controlled Trial Simulating Point-of-Care Infant Testing
Creators: name: Maliwichi, Madalitso
name: McCollum, Eric D.
name: Horst, Charles van der
name: Preidis, Geoffrey A.
name: Kazembe, Peter N.
name: Hoffman, Irving
name: Hosseinipour, Mina C.
name: McCrary, L. Madeline
name: Olson, Dan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Many African infants fail to receive their diagnostic HIV molecular test results and subsequently, antiretroviral therapy (ART). To determine whether a point-of-care molecular HIV test increases ART access for hospitalized Malawian infants, we simulated a point-of-care test using rapid HIV RNA polymerase chain reaction (Rapid PCR) and compared patient outcomes to an optimized standard care that included assessment with the World Health Organization (WHO) clinical algorithm for HIV infection plus a DNA PCR with a turnaround time of several weeks (standard care).
Large language models for epidemiological research via automated machine learning
Creators: name: Wibaek, Rasmus
name: Hulman, Adam
Publisher: name: figshare
Year: 2022
Subjects: subject: 111706 Epidemiology
subject: FOS: Health sciences
subject: 80107 Natural Language Processing
subject: FOS: Computer and information sciences

description: This poster was designed by Rasmus Wibaek and Adam Hulman, for the 'Danish Data Science 2022' conference, and presented by AH on Nov 8, 2022.
 The study was conducted in collaboration with Gregers Stig Andersen, Christina C. Dahm and Daniel R. Witte. The full manuscript is available online as a preprint.
La carriera teatrale di ‘A Harlot’s Progress’ di William Hogarth
Creators: name: Barbieri, Maria Chiara
Publisher: name: Drammaturgia
Year: 2017

description: The ‘theatrical career’ of William Hogarth’s series A Harlot’s Progress reached its peak in 1733, when the «grotesque pantomime» by Theophilus Cibber The Harlot’s Progress, or The Ridotto al Fresco was staged at Drury Lane Theatre in London. The scenario is here published in the original English and in Italian translation, preceded by an essay that examines features and theatrical fortune of the pantomime and some aspects of the careers of Hogarth and Cibber.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
Interplay between the conserved pore residues Thr-91 and His-209 controls formate translocation through the FocA channel
Creators: name: Kammel, Michelle
name: Trebbin, Oliver
name: Sawers, Robert Gary
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 570

description: The formate channel A (FocA) belongs to the formate-nitrite transporter (FNT) family, members of which permeate small monovalent anions. FocA from Escherichia coli translocates formate/formic acid bi-directionally across the cytoplasmic membrane during fermentative growth. Two residues are particularly well-conserved within the translocation pores of FNTs: threonine-91 and histidine-209, based on E. coli FocA numbering. These residues are located at the tips of two broken transmembrane helices and control anion passage. H209 is the only charged residue within the pore and interacts with T91. Here, we addressed the role of the T91-H209 interaction network in the permeation of formate in vivo through FocA by performing an extensive amino acid-exchange study. Monitoring changes in intracellular formate using a formate-responsive fdhFP::lacZ reporter system revealed that T91 is essential for the ability of FocA to translocate formate bi-directionally. Only exchange for serine was partially tolerated, indicating that the hydroxyl group of T91 is mechanistically important. Substitution of H209 with N or Q was previously shown to convert FocA into a formate efflux channel. We show here that residue exchanges A, I, and T at this position resulted in a similar phenotype. Moreover, efflux function was confirmed for these FocA variants by measuring excreted formate in the culture medium. Substitution of bulky or charged residues for H209 prevented bi-directional formate passage. Studies using hypophosphite, a toxic analogue of formate taken up by FocA, and which causes impaired growth, confirmed that T91 and H209 substitutions essentially abolished, or drastically reduced, FocA’s translocation activity, as shown by effects on growth rate. The exceptions were T91S- and T91Y-exchange variants that retained partial ability to take up inhibitory hypophosphite. Together, our findings indicate that T91 is essential for formate permeation in both directions; however, it is particularly important to allow anion efflux. Moreover, H209 is essential for formate uptake by FocA, strongly suggesting that protonation-deprotonation of this residue plays a role in formate uptake. Finally, our results substantiate the premise that efflux and influx of formate by FocA are mechanistically distinct processes that are controlled by the interplay between T91 and H209.
CARCA: Context and Attribute-Aware Next-Item Recommendation via Cross-Attention
Creators: name: Rashed, Ahmed
name: Elsayed, Shereen
name: Schmidt-Thieme, Lars
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Retrieval (cs.IR)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: In sparse recommender settings, users' context and item attributes play a crucial role in deciding which items to recommend next. Despite that, recent works in sequential and time-aware recommendations usually either ignore both aspects or only consider one of them, limiting their predictive performance. In this paper, we address these limitations by proposing a context and attribute-aware recommender model (CARCA) that can capture the dynamic nature of the user profiles in terms of contextual features and item attributes via dedicated multi-head self-attention blocks that extract profile-level features and predicting item scores. Also, unlike many of the current state-of-the-art sequential item recommendation approaches that use a simple dot-product between the most recent item's latent features and the target items embeddings for scoring, CARCA uses cross-attention between all profile items and the target items to predict their final scores. This cross-attention allows CARCA to harness the correlation between old and recent items in the user profile and their influence on deciding which item to recommend next. Experiments on four real-world recommender system datasets show that the proposed model significantly outperforms all state-of-the-art models in the task of item recommendation and achieving improvements of up to 53% in Normalized Discounted Cumulative Gain (NDCG) and Hit-Ratio. Results also show that CARCA outperformed several state-of-the-art dedicated image-based recommender systems by merely utilizing image attributes extracted from a pre-trained ResNet50 in a black-box fashion.
Factors Associated With Delayed Hepatitis B Viral Suppression on Tenofovir Among Patients Coinfected With HBV-HIV in the CNICS Cohort
Creators: name: Kim, H. Nina
name: Geng, Elvin
name: Boswell, Stephen
name: Crane, Heidi M.
name: Moore, Richard
name: Rodriguez, Benigno
name: Martin, Jeffrey
name: Van Rompaey, Stephen
name: Saag, Michael S.
name: Mathews, W. Christopher
name: Thio, Chloe L.
name: Kitahata, Mari M.
name: Overton, Edgar T.
name: Eron, Joseph J.
name: Mugavero, Michael
name: Rodriguez, Carla V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Despite widespread use in HIV and hepatitis B virus (HBV) infection, the effectiveness of tenofovir (TDF) has not been studied extensively outside of small HBV-HIV coinfected cohorts. We examined the effect of prior lamivudine treatment (3TC) and other factors on HBV DNA suppression with TDF in a multi-site clinical cohort of coinfected patients.
« Les savoirs des acteurs italiens » : une collection numérique pour la mémoire des savoirs
Creators: name: De Luca, Emanuele
Publisher: name: Drammaturgia
Year: 2017

description: In the context of the profound changes that the scientific community is facing within the new epistemological processes and research, inspired and provoked by the new digital era, new technologies and the web, this article aims to address the relationship between the history of theater and the modern digital humanities, through the digital collection «Les savoirs des acteurs italiens», directed by Andrea Fabiano at the IRPMF. Firstly, we shall question the last decade historiographical acquisitions that the collection offers about the cultural and theatrical exchanges between France and Italy in the 18th century and, secondly, the analysis instruments and availability of the data in the context of the new digital humanities. The role of the Comédie-Italienne in Paris for the transmission of the knowledge is also the key to the understating of the frame within which this knowledge is collocated, a domain that is both theatrical and musical, Italian as French. Similarly, this collection might be considered a melting point between the past and the present of the paper book and the digital documentation. It is also projected towards a future in which, increasingly, the new instruments will offer a different fruition of the materials and of the research experiences.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
The combination of vermicompost and arbuscular mycorrhizal fungi improves the physiological properties and chemical composition of Opuntia ficus-indica under semi-arid conditions in the field
Creators: name: Lahbouki, Soufiane
name: Ben-Laouane, Raja
name: Outzourhit, Abdelkader
name: Meddich, Abdelilah
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Drought is one of the major threats to food security in arid and semi-arid regions. Therefore, significant changes in agricultural production systems will be required to meet the challenges of food security while addressing water scarcity. Prickly pear is a drought tolerant plant, as well as a source of sustainable food and feed. Nonetheless, in dry conditions, its growth and performance are restricted. The aim of this study was to evaluate the effect of arbuscular mycorrhizal fungi (AMF), vermicompost (Vc) or the combination of AMF + Vc on yield, growth and physio-chemical parameters of cactus grown under field drought conditions. Two irrigation regimes were applied, non-irrigated (grown under rainfed conditions) and irrigated plants (8 mm of water per week). After eight months of cultivation, the finding demonstrated that drought reduced growth, physiological and biochemical parameters of cactus. However, the application of biostimulants, especially Vc and AMF + Vc, can mitigate the negative effect of drought by increasing cladode dry weight (93% and 109%), total chlorophyll (78% and 75%), total phenolic content (83% and 81%). Those treatments are also efficient in enhancing activities of enzymatic and non enzymatic antioxidants in cactus cladodes and fruits. These results suggest that the use of these biostimulants can mitigate the challenges associated with drought, by improving the physiological and biochemical responses of cactus.
Geometric integration of classical spin dynamics via a mean-field Schrödinger equation
Creators: name: Dahlbom, David
name: Zhang, Hao
name: Miles, Cole
name: Bai, Xiaojian
name: Batista, Cristian D.
name: Barros, Kipton
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The Landau-Lifshitz equation describes the time-evolution of magnetic dipoles, and can be derived by taking the classical limit of a quantum mechanical spin Hamiltonian. To take this limit, one constrains the many-body quantum state to a tensor product of coherent states, thereby neglecting entanglement between sites. Expectation values of the quantum spin operators produce the usual classical spin dipoles. One may also consider expectation values of polynomials of the spin operators, leading to quadrupole and higher-order spin moments, which satisfy a dynamical equation of motion that generalizes the Landau-Lifshitz dynamics [Zhang and Batista, Phys. Rev. B 104, 104409 (2021)]. Here, we reformulate the dynamics of these $N^2-1$ generalized spin components as a mean-field Schrödinger equation on the $N$-dimensional coherent state. This viewpoint suggests efficient integration methods that respect the local symplectic structure of the classical spin dynamics.
Alle origini della storia degli attori. Francesco S. Bartoli, Pietro Antonio Colomberti, Luigi Rasi
Creators: name: Simoncini, Francesca
Publisher: name: Drammaturgia
Year: 2017

description: The section is devoted to the biographical profiles of Francesco Saverio Bartoli (1745-1806), Antonio Colomberti (1806-1892), Luigi Rasi (1852-1918). Theatre professionals themselves, they narrated the lives of their colleagues. Their biographical dictionaries are still to be regarded today as important tools for studying the history of theatre and of italian actors.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
FEM-PrEP: Adherence Patterns and Factors Associated With Adherence to a Daily Oral Study Product for Pre-exposure Prophylaxis
Creators: name: Taylor, Doug
name: Corneli, Amy L.
name: Kashuba, Angela
name: Deese, Jennifer
name: Lombaard, Johan
name: Agot, Kawango
name: Wang, Meng
name: Van Damme, Lut
name: Kapiga, Saidi
name: Ahmed, Khatija
name: Manongi, Rachel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Background:Several clinical trials have demonstrated the safety and effectiveness of oral tenofovir disoproxil fumarate (TDF), with or without emtricitabine (FTC), as pre-exposure prophylaxis (PrEP) for reducing the risk of HIV acquisition. Adherence to the study product was insufficient to demonstrate the effectiveness of FTC/TDF in 2 PrEP clinical trials conducted among women (FEM-PrEP and the Vaginal and Oral Interventions to Control the Epidemic study), but further analyses of adherence in these studies may inform PrEP demonstration projects and future HIV prevention clinical trials.Methods:We randomly selected a subcohort of 150 participants randomized to FTC/TDF in 3 FEM-PrEP sites (Bondo, Kenya; Bloemfontein, South Africa; and Pretoria, South Africa) to examine adherence levels over time and to assess factors associated with adherence, based on plasma tenofovir and intracellular tenofovir diphosphate drug concentrations in specimens collected at 4-week visit intervals.Results:We observed drug concentrations consistent with good adherence in 28.5% of all visit intervals when drug was available to use, but only 12% of participants achieved good adherence throughout their study participation. In multivariate analysis, the Bloemfontein site [odds ratio (OR): 2.43; 95% confidence interval (CI): 1.32 to 4.48] and liking the pill color (OR: 2.93; 95% CI: 1.18 to 7.27) were positively associated with good adherence, whereas using oral contraceptive pills at enrollment was negatively associated with good adherence (OR: 0.37; 95% CI: 0.18 to 0.74).Conclusions:Most participants did not regularly adhere to the study product throughout their trial participation, although a small minority did. Few factors associated with good adherence to the study product were identified in FEM-PrEP.
Francesco Saverio Bartoli
Creators: name: Spinelli, Leonardo
Publisher: name: Drammaturgia
Year: 2017

description: A modestly talented actor and playwright, Bartoli acted with his wife Teodora Medebach in the theatre company directed by Antonio Sacco from 1771 to 1777. Sick with tuberculosis, he precociously retired from the stage to become a bookseller. He is renown as the author of the first biographical dictionary of italian actors, published in 1782. Conversely, the majority of his scholarly writings and historical-artistic works remain unpublished.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
Plant-soil interactions in response to grazing intensity in a semi-arid ecosystem from NE Spain
Creators: name: Navarro-Perea, Manuel
name: Pueyo, Yolanda
name: Moret, David
name: Valverde, Ángel
name: Igual, José Mariano
name: Alados, Concepción L.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Livestock grazing is an important element in ecosystem regulation since it may affect essential ecosystem functions, such as nutrient acquisition, organic matter decomposition, or litter accumulation in the soil. Overgrazing can threaten the conservation of ecosystems through excessive defoliation of plants or trampling. On the contrary, moderate grazing can have benefits on ecosystem dynamics by favoring nutrient cycling or the soil microbial activity. The aim of this study was to analyze these effects in a semi-arid Mediterranean shrubland located in NE Spain. We established six study sites including three grazing intensities, where we sampled vegetation biomass and soil properties: nitrogen content, microbial biomass, water infiltration capacity, porosity, and gypsum content. These parameters were included in a plant-soil interaction model tested through Structural Equation Modeling. Grazing had a direct negative effect on plant biomass (p < 0.01) and water infiltration capacity (p < 0.05) affecting soil nitrogen content (p < 0.001) and microbial biomass (p < 0.5), respectively. Infiltration capacity and porosity were primary drivers of plant biomass (p < 0.05, both cases), and plant biomass was the main contributor to the soil nitrogen pool. Microbial biomass was dependent on infiltration capacity (p < 0.05), porosity (p < 0.01), and nitrogen (p < 0.01). Grazing directly or indirectly affected the functioning of the ecosystem through effects on plant and soil attributes, which may result in changes in plant growth, litter decomposition, or plant nutrient acquisition. This study revealed that moderate grazing can maintain optimal ecosystem features and prevent ecosystem degradation.
An iterative data-driven turbulence modeling framework based on Reynolds stress representation
Creators: name: Yin, Yuhui
name: Zhang, Yufei
name: Chen, Haixin
name: Fu, Song
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Data-driven turbulence modeling studies have reached such a stage that the fundamental framework is basically settled, but several essential issues remain that strongly affect the performance, including accuracy, smoothness, and generalization capacity. Two problems are studied in the current research: (1) the processing of the Reynolds stress tensor and (2) the coupling method between the machine learning turbulence model and flow solver. The first determines the form of predicting targets and the resulting physical completeness and interpretability. The second determines the training process and intrinsic relevance between the mean flow features and Reynolds stress. For the Reynolds stress processing issue, we perform the theoretical derivation to extend the relevant tensor arguments of Reynolds stress in addition to the strain rate and rotation rate. Then, the tensor representation theorem is employed to give the complete irreducible invariants and integrity basis. In addition, an adaptive regularization term is employed to enhance the representation performance. For the coupling issue, an iterative coupling data-driven turbulence modeling framework with consistent convergence is proposed. The training data preparation, predicting target selection, and computation platform are illustrated. The framework is then applied to a canonical separated flow for verification. The mean flow results obtained by coupling computation of the trained machine learning model and flow solver have high consistency with the direct numerical simulation true values, which proves the validity of the current approach.
Pietro Antonio Colomberti
Creators: name: Bentoglio, Alberto
Publisher: name: Drammaturgia
Year: 2017

description: This paper presents the theatrical life of Antonio Colomberti. He was born in Viterbo on February 20, 1806 and died in Bologna on March 13, 1892, at the age of eighty-six. Throughout his long life, Colomberti played a variety of characters and directed some of the most important Italian theatre companies. In addition, he wrote and translated tragedies, comedies and historical dramas. His most important works are his autobiographical Memoirs and the Dictionary of Italian Actors. Colomberti wrote three versions of his Dictionary that consists of 1,400 biographical entries, in alphabetical order, preceded by extensive historical introductions.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
Homogeneous electron liquid in arbitrary dimensions beyond the random phase approximation
Creators: name: Duc Pham, L. V.
name: Sattler, Pascal
name: Marques, Miguel
name: Benavides-Riveros, Carlos L.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 530

description: The homogeneous electron liquid is a cornerstone in quantum physics and chemistry. It is an archetypal system in the regime of slowly varying densities in which the exchange-correlation energy can be estimated with many methods. For high densities, the behavior of the ground-state energy is well-known for 1, 2, and 3 dimensions. Here, we extend this model to arbitrary integer dimensions and compute its correlation energy beyond the random phase approximation (RPA). We employ the approach developed by Singwi, Tosi, Land, and Sjölander (STLS), whose description of the electronic density response for 2D and 3D for metallic densities is known to be comparable to Quantum Monte-Carlo. For higher dimensions, we compare the results obtained for the correlation energy with the values previously obtained using RPA. We find that in agreement with what is known for 2 and 3 dimensions, the RPA tends to over-correlate the liquid also at higher dimensions. We furthermore provide new analytical formulae for the unconventional-dimensional case both for the real and imaginary parts of the Lindhard polarizability and for the local field correction of the STLS theory, and illustrate the importance of the plasmon contribution at those high dimensions.
HIV Self-Testing Among Online MSM in China: Implications for Expanding HIV Testing Among Key Populations
Creators: name: Meng, Gang
name: Tucker, Joseph D.
name: Liu, Fengying
name: Emch, Michael E.
name: Han, Larry
name: Bien, Cedric H.
name: Muessig, Kathryn E.
name: Wei, Chongyi
name: Yang, Ligang
name: Yang, Min
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: HIV self-testing offers an alternative to facility-based testing that could expand HIV testing among MSM. We organized an online survey of MSM in China to better understand the frequency and correlates of HIV self-testing. A total of 1342 individuals completed the survey. 20.3% of MSM reported prior HIV self-testing. Self-testing was correlated with being married, having six or greater male anal sex partners in the past three months, and having HIV tested within 12 months in the multivariable analysis. Our study suggests that HIV self-testing may be able to reach sub-groups of high-risk MSM and enable more frequent HIV testing.
Supporting information from Phylogenetic meta-analysis reveals system-specific behavioural type – behavioural predictability correlations
Creators: name: Horváth, Gergely
name: Garamszegi, László Zsolt
name: Herczeg, Gábor
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Animal Behaviour

description: The biological significance of behavioural predictability (environment-independent within-individual behavioural variation) became accepted recently as an important part of an individual's behavioural strategy besides behavioural type (individual mean behaviour). However, we do not know how behavioural type and predictability evolve. Here, we tested different evolutionary scenarios: (i) the two traits evolve independently (lack of correlations), (ii) the two traits' evolution is constrained (abundant correlations) either due to (ii/a) proximate constraints (direction of correlations is similar) or (ii/b) local adaptations (direction of correlations is variable). We applied a set of phylogenetic meta-analyses based on 93 effect sizes across 44 vertebrate and invertebrate species, focusing on activity and risk-taking. The general correlation between behavioural type and predictability did not differ from zero. Effect sizes for correlations showed considerable heterogeneity, with both negative and positive correlations occurring. The overall absolute (unsigned) effect size was high (Zr = 0.58), and significantly exceeded the null expectation based on randomized data. Our results support the adaptive scenario: correlations between behavioural type and predictability are abundant in nature, but their direction is variable. We suggest that the evolution of these behavioural components might be constrained in a system-specific way.
Sustained growth factor delivery from bioactive PNIPAM-grafted-chitosan/heparin multilayers as a tool to promote growth and migration of cells
Creators: name: Lu, Yi-Tung
name: Hung, Pei-Tzu
name: Zeng, Kui
name: Menzel, Matthias
name: Schmelzer, Christian E. H.
name: Zhang, Kai
name: Groth, Thomas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 615

description: Delivery of growth factors (GFs) is challenging for regulation of cell proliferation and differentiation due to their rapid inactivation under physiological conditions. Here, a bioactive polyelectrolyte multilayer (PEM) is engineered by the combination of thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) and glycosaminoglycans to be used as reservoir for GF storage. PNIPAM-grafted-chitosan (PChi) with two degrees of substitution (DS) are synthesized, namely LMW* (DS 0.14) and HMW (DS 0.03), by grafting low (2 kDa) and high (10 kDa) molecular weight of PNIPAM on the backbone of chitosan (Chi) to be employed as polycations to form PEM with the polyanion heparin (Hep) at pH 4. Subsequently, PEMs are chemically crosslinked to improve their stability at physiological pH 7.4. Resulting surface and mechanical properties indicate that PEM containing HMW is responsive to temperature at 20 °C and 37 °C, while LMW is not. More importantly, Hep as terminal layer combined with HMW allows not only a better retention of the adhesive protein vitronectin but also a sustained release of FGF-2 at 37 °C. With the synergistic effect of vitronectin and matrix-bound FGF-2, significant promotion on adhesion, proliferation, and migration of 3T3 mouse embryonic fibroblasts is achieved on HMW-containing PEM compared to Chi-containing PEM and exogenously added FGF-2. Thus, PEM containing PNIPAM in combination with bioactive glycosaminoglycans like Hep represents a versatile approach to fabricate a GF delivery system for efficient cell culture, which can be potentially served as cell culture substrate for production of (stem) cells and bioactive wound dressing for tissue regeneration.
Agelena limbata Thorell 1879
Creators: name: Marusik, Yuri M.
name: Koponen, Seppo
Publisher: name: Zenodo
Year: 2000
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Agelenidae
Agelena
Agelena limbata

description: Agelena limbata Thorell, 1879 Agelena silvatica Oligcr, 1983: 628, figs. 7 -1 1, syn.n. Material examined: 3♂ ♀, [10] S part Ussuri Reserve, 43º39'N 132º33'E, 29- 31.07.1998, YM; 1 ♀, [09] env. of Anisimovka Vill, 43º10'N 132º46' E, 24- 28.07.1998, YM; 2♀♀ [17] Lazovski Reserve, Korpad' Camp, 43°16'N 134º08' E, 6— 9.08.1998, YM. COMMENTS. It is a rather common species in the Rus­ sian Far East. Study o f the topotype material o f A. silvatica proved identity of this species and A. limbata.
description: Published as part of Marusik, Yuri M. & Koponen, Seppo, 2000, New data on spiders (Aranei) from the Maritime Province, Russian Far East, pp. 55-68 in Arthropoda Selecta 9 (1) on page 56, DOI: 10.5281/zenodo.822713
description: {"references": ["Oliger T. I. 1983. New species of spider families (Pholcidae, Clubionidae, Agelcnidae) from the Lazovskiy State Reserve / / Zool. Zhurn. Vol. 62. No. 4. P. 627 - 629 [in Russian, with English summary],"]}
Luigi Rasi
Creators: name: Simoncini, Francesca
Publisher: name: Drammaturgia
Year: 2017

description: An atypical actor of the 19th century theatre world, Luigi Rasi retired from the stage early to assume, in 1882, the direction of the Royal Acting School in Florence. His most famous work, I Comici italiani. Biografia, Bibliografia, Iconografia, a two-volume biographical dictionary (1897-1905), is still regarded today as a precious source for the history of actors. The bibliographical and documentary material gathered by Rasi during his studies is kept at the Museo Biblioteca of Burcardo in Rome.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
Repositioning ethnicity and transnationalism : community resilience strategies among the non-migratory segment of Turkish Jewry
Creators: name: Moreno, Aviad
name: Karkason, Tamir
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 296

description: The methods that communities exploit to cope with national hegemonies that dispossess and exclude them have attracted the interest of migration scholars who emphasize the development of transnational strategies as community-building vehicles. Some scholars focus on migrant communities, whereas other studies analyze the “stayers”—those who remain in the countries of origin—in their analyses of the impacts of transnational trends on these groups. Yet how such transnational dynamics influence the “stayers” among ethnonational communities whose members rapidly “repatriate” en masse to their perceived nation-state, such as the migration of Middle Eastern Jews to Israel in the era of regional decolonization and nationalization, remain understudied. This article focuses on the community of “stayers” among Turkish Jews, whose leaders sought methods to cope with the effects of rising nationalism on their community structure and the intensity of an emigration crisis that engulfed them due to the vacuum they faced after losing 40 percent of their members in 1948–1949 to Israel. We analyze Şalom, the most important newspaper that Turkish Jewry continued to publish well after 1948. To escape marginalization and to re-establish their base in Turkey, one of Şalom’s main strategies, we find, is conveying to its readership in Turkey the advantage of connecting and twinning the two national centers that had become the focal points of most of the community by 1950—the Turkish Republic and the State of Israel.
Le statue del Cristo crocifisso e morto nelle azioni drammatiche della Passione (XIV-XV secolo). Linee di ricerca
Creators: name: Bino, Carla
Publisher: name: Drammaturgia
Year: 2017

description: This paper intends to provide an initial draft and a methodological framework for further investigations about the use of the statues of the crucified and dead Christ during the representations of the Passion from the XIV to the XV century. In particular, I will discuss four different types of artifact: crucifixes with moveble arms; so-called ‘talking’ crucifixies that have unmoveble limbs but a moveble tongue; jointed sculptures of the suffering Christ and artifacts made with several materials, coated with leather and totally jointed; carved statues of the dead Christ lying in a wooden sarcophagus covered with paintings. My proposal is to distinguish them according to those features that link to different performative actions and, therefore, to different rites celebrated in different spiritual contexts. I consider each of these artworks as a ‘performative image’, that was probably used for a specific performance, playing a certain scene on a very clear ‘stage’ in front of a particular audience.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
Managing Multiple Funding Streams and Agendas to Achieve Local and Global Health and Research Objectives: Lessons From the Field
Creators: name: Chi, Benjamin
name: Sikazwe, Izukanji
name: Chi, Harmony
name: Kapambwe, Sharon
name: Chilengi, Roma
name: Wambulawae, Inonge
name: Simbeye, Darius
name: Silwizya, Geoffrey
name: Godfrey, Katy
name: Topp, Stephanie M.
name: Holmes, Charles B.
name: Raelly, Roselyne L.
name: Sibajene, Sheila
name: Henostroza, German
name: Freeman, Bethany L.
name: Moore, Carolyn Bolton
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Multiple funding sources provide research and program implementation organizations a broader base of funding and facilitate synergy, but also entail challenges that include varying stakeholder expectations, unaligned grant cycles, and highly variable reporting requirements. Strong governance and strategic planning are essential to ensure alignment of goals and agendas. Systems to track budgets and outputs as well as procurement and human resources are required. A major goal is to transition leadership and operations to local ownership. This article details successful approaches used by the newly independent non-governmental organization, the Centre for Infectious Disease Research in Zambia (CIDRZ).
The Arkansas Poll: October 2005
Creators: name: Politics, Diane D. Blair Center Of Southern
Publisher: name: Roper Center for Public Opinion Research
Year: 2023

description: Most pressing issue/problem facing people in Arkansas (3); quality of life (3); evaluation of public officials (5); term limits law (2); school maintenance and operation (2); usage of state resources for new businesses (2); motivation for voting (2); marriage definition (2); gun control (3); abortion (3); medical marijuana (2); trust in government (3); health insurance (11); water quality (10).
Phylogenetic Studies of Transmission Dynamics in Generalized HIV Epidemics: An Essential Tool Where the Burden is Greatest?
Creators: name: Pillay, Deenan
name: Dennis, Ann M.
name: Fraser, Christophe
name: Cohen, Myron S.
name: Herbeck, Joshua T.
name: Kellam, Paul
name: de Oliveira, Tulio
name: Brown, Andrew L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Efficient and effective HIV prevention measures for generalized epidemics in sub-Saharan Africa have not yet been validated at the population-level. Design and impact evaluation of such measures requires fine-scale understanding of local HIV transmission dynamics. The novel tools of HIV phylogenetics and molecular epidemiology may elucidate these transmission dynamics. Such methods have been incorporated into studies of concentrated HIV epidemics to identify proximate and determinant traits associated with ongoing transmission. However, applying similar phylogenetic analyses to generalized epidemics, including the design and evaluation of prevention trials, presents additional challenges. Here we review the scope of these methods and present examples of their use in concentrated epidemics in the context of prevention. Next, we describe the current uses for phylogenetics in generalized epidemics, and discuss their promise for elucidating transmission patterns and informing prevention trials. Finally, we review logistic and technical challenges inherent to large-scale molecular epidemiological studies of generalized epidemics, and suggest potential solutions.
Palladium and platinum complexes of the antimetabolite fludarabine with vastly enhanced selectivity for tumour over non-malignant cells
Creators: name: Schleser, Sebastian W.
name: Krytovych, Oleksandr
name: Ziegelmeier, Tim
name: Groß, Elisabeth
name: Kasparkova, Jana
name: Brabec, Viktor
name: Weber, Thomas
name: Schobert, Rainer
name: Mueller, Thomas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: The purine derivative fludarabine is part of frontline therapy for chronic lymphocytic leukaemia (CLL). It has shown positive effects on solid tumours such as melanoma, breast, and colon carcinoma in clinical phase I studies. As the treatment of CLL cells with combinations of fludarabine and metal complexes of antitumoural natural products, e.g., illudin M ferrocene, has led to synergistically enhanced apoptosis, in this research study different complexes of fludarabine itself. Four complexes bearing a trans-[Br(PPh3)2]Pt/Pd fragment attached to atom C-8 via formal η1-sigma or η2-carbene bonds were synthesised in two or three steps without protecting polar groups on the arabinose or adenine. The platinum complexes were more cytotoxic than their palladium analogues, with low single-digit micromolar IC50 values against cells of various solid tumour entities, including cisplatin-resistant ones and certain B-cell lymphoma and CLL, presumably due to the ten-fold higher cellular uptake of the platinum complexes. However, the palladium complexes interacted more readily with isolated Calf thymus DNA. Interestingly, the platinum complexes showed vastly greater selectivity for cancer over non-malignant cells when compared with fludarabine.
Postpartum Depression and HIV Infection Among Women in Malawi
Creators: name: Dow, Anna
name: Van Rie, Annelies
name: Pence, Brian W.
name: Dube, Queen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: HIV-infected women face several risk factors for postpartum depression (PPD). We aimed to describe the prevalence and cumulative incidence of PPD in the low-income setting of Malawi, and to determine the association between maternal and infant HIV and PPD.
‘Terentius cum figuris’ (preliminari a una ricerca)
Creators: name: Vescovo, Piermario
Publisher: name: Drammaturgia
Year: 2017

description: Notoriously, Terence’s comedies are the only tradition that comes from ancient times, through the centuries, accompanied by a set of images. Drawing the lines of a wider research, the essay suggests that the first modern edition cum figures (Lyon 1493) funds his project and his ‘comments for images’, which accompanies the commentary of words, on the late ancient tradition. In this perspective, the transmission and interpretation of elements of material culture of the ancient theater take on a different meaning, offered and turned across the images.
description: Drammaturgia, Vol 13 No 3 (2016): Anno XIII / n.s. 3 – 2016
Agelenopsis potteri Blackwall 1846
Creators: name: Marusik, Yuri M.
name: Koponen, Seppo
Publisher: name: Zenodo
Year: 2000
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Agelenidae
Agelenopsis
Agelenopsis potteri

description: Agelenopsis potteri (Blackwall, 1846) ** Chamberlin & Ivie, 1941: f. 3, 17, 42; Lehtinen, 1967: f. 248. Material examined 1 ♂, env. of Vladivostok, Okeanskaya, forest litter, 2.10.1997, YM; 1 ♂, Lazo Town, 43º22.7'N 133º54'E, in buildings, 11.1998 -03.1999. YS. Comparative material: 1 ♂ (BMM ♂ 7828), Washington, Jefferson Co. Quilcene/Cemetery Rd„ 70, 57.831ºN 122.884°W, 10.09.1991, I.E. Richards; 1 ♂ (BMM ♂ 8122), same state, Snohomish Co., Crabapple Lake, 420 ', 48.13°N 122.27ºW, 5.09.1966, J.R. Thomson; 1 ♂ (BMM ♂ 7403), same state, Chelan Co., Wenatchee, 815 ' 47.418ºN 120.328ºW, 10.09.1981, D. Carroll. COMMENTS. Agelenopsis is a Nearctic genus.A. potteri is known to be distributed from Pacific to Atlantic coasts of North America [Chamberlin & Ivie, 1941] as well as intro­ duced in Kirghizia [Zonstein et al., 1996], It has been also introduced in the M aritime Province from western USA. First male was found less than a hundred meter from “American V illage”, built for employers o f American Consulate and trade center in the vicinity o f Vladivostok. There seems to be two species in Nearctic treated under the same name. W ithin 3 males studied from W ashington State (see material) two are similar as illustrated by Chamber­ lin & Ivie [1941] while male from, Jefferson Co, is different and has similar palp as specimens from the Maritime Province (with wider course o f embolus).
description: Published as part of Marusik, Yuri M. & Koponen, Seppo, 2000, New data on spiders (Aranei) from the Maritime Province, Russian Far East, pp. 55-68 in Arthropoda Selecta 9 (1) on page 56, DOI: 10.5281/zenodo.822713
description: {"references": ["Chamberlin R. V., Ivie W. 1941. North American Agelenidae of the genera Agelcnopsis, Calilena, Ritalena and Tortolena / / Ann. Ent. Soc. Amer. Vol. 34. Nb, 3. P. 585 - 628.", "Lehtinen P. T. 1967. Classification of the Cribellate spiders and some allied families, with notes on the evolution of the suborder Araneomorpha / / Ann. Zool. Fennici. Vol. 4. No. 3. P. 199 - 467.", "Zonstein S. I., Gromov A. V, Zyuzin AA, Ovchinnikov S. V. 1996. Class Arachnida - terrestrial arachnids. Order Araneae - spiders / / Kadastr geneticheskogo fonda Kyrgyzstana. T. 2. Bishkek. P. 132 - 153 [in- Russian],"]}
Bioactivity and corrosion behavior of magnesium barrier membranes
Creators: name: Hornberger, Helga
name: Kissel, Hannah
name: Striegl, Birgit
name: Kronseder, Matthias
name: Vollnhals, Florian
name: Christiansen, Silke
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: bioactivity, corrosion rate, degradation, dental membrane, magnesium
subject: 530 Physik

description: In the current research, magnesium and its alloys have been intensively studied as resorbable implant materials. Magnesium materials combine their good mechanical properties with bioactivity, which make them interesting for guided bone regeneration and for the application as barrier membranes. In this study, the in vitro degradation behavior of thin magnesium films was investigated in cell medium and simulated body fluid. Three methods were applied to evaluate corrosion rates: measurements of (i) the gaseous volume evolved during immersion, (ii) volume change after immersion, and (iii) polarization curves. In this comparison, measurements of H2 development in Dulbecco's modified Eagle's medium showed to be the most appropriate method, exhibiting a corrosion rate of 0.5 mm·year−1. Observed oxide and carbon contamination have a high impact on controlled degradation, suggesting that surface treatment of thin foils is necessary. The bioactivity test showed positive results; more detailed tests in this area are of interest.
Time- and concentration-dependent adverse effects of Paclitaxel on non-neuronal cells in rat primary dorsal root ganglia
Creators: name: Elfarnawany, Amira
name: Dehghani, Faramarz
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Paclitaxel is a chemotherapeutic agent used to treat a wide range of malignant tumors. Although it has anti-tumoral properties, paclitaxel also shows significant adverse effects on the peripheral nervous system, causing peripheral neuropathy. Paclitaxel has previously been shown to exert direct neurotoxic effects on primary DRG neurons. However, little is known about paclitaxel’s effects on non-neuronal DRG cells. They provide mechanical and metabolic support and influence neuronal signaling. In the present study, paclitaxel effects on primary DRG non-neuronal cells were analyzed and their concentration or/and time dependence investigated. DRGs of Wister rats (6–8 weeks old) were isolated, and non-neuronal cell populations were separated by the density gradient centrifugation method. Different concentrations of Paclitaxel (0.01 µM–10 µM) were tested on cell viability by MTT assay, cell death by lactate dehydrogenase (LDH) assay, and propidium iodide (PI) assay, as well as cell proliferation by Bromodeoxyuridine (BrdU) assay at 24 h, 48 h, and 72 h post-treatment. Furthermore, phenotypic effects have been investigated by using immunofluorescence techniques. Paclitaxel exhibited several toxicological effects on non-neuronal cells, including a reduction in cell viability, an increase in cell death, and an inhibition of cell proliferation. These effects were concentration- and time-dependent. Cellular and nuclear changes such as shrinkage, swelling of cell bodies, nuclear condensation, chromatin fragmentation, retraction, and a loss in processes were observed. Paclitaxel showed adverse effects on primary DRG non-neuronal cells, which might have adverse functional consequences on sensory neurons of the DRG, asking for consideration in the management of peripheral neuropathy.
MIRACUM-Pipe : an adaptable pipeline for next-generation sequencing analysis, reporting, and visualization for clinical decision making
Creators: name: Metzger, Patrick
name: Hess, Maria Elena
name: Blaumeiser, Andreas
name: Pauli, Thomas
name: Schipperges, Vincent
name: Mertes, Ralf
name: Christoph, Jan
name: Unberath, Philipp
name: Reimers, Niklas
name: Scheible, Raphael
name: Illert, Anna Lena
name: Busch, Hauke
name: Andrieux, Geoffroy
name: Börries, Melanie
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: (1) Background: Next-generation sequencing (NGS) of patients with advanced tumors is becoming an established method in Molecular Tumor Boards. However, somatic variant detection, interpretation, and report generation, require in-depth knowledge of both bioinformatics and oncology. (2) Methods: MIRACUM-Pipe combines many individual tools into a seamless workflow for comprehensive analyses and annotation of NGS data including quality control, alignment, variant calling, copy number variation estimation, evaluation of complex biomarkers, and RNA fusion detection. (3) Results: MIRACUM-Pipe offers an easy-to-use, one-prompt standardized solution to analyze NGS data, including quality control, variant calling, copy number estimation, annotation, visualization, and report generation. (4) Conclusions: MIRACUM-Pipe, a versatile pipeline for NGS, can be customized according to bioinformatics and clinical needs and to support clinical decision-making with visual processing and interactive reporting.
Pregnancy Intentions Among Women Living With HIV in the United States
Creators: name: Stewart, Amanda
name: Sturdevant, Marcia S.
name: Rana, Aadia
name: Nguyen, Minh Ly
name: Cohn, Susan E.
name: Ellis, Pamala
name: Levison, Judy
name: Lazenby, Gweneth B.
name: Tandon, Richa
name: Badell, Martina
name: Kempf, Mirjam-Colette
name: Stewart, Robert D.
name: Rahangdale, Lisa
name: Cohan, Deborah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The number of HIV-infected women giving birth in the U.S. is increasing. Research on pregnancy planning in HIV-infected women is limited.