cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Body image concerns in men with localized prostate cancer
Creators: name: Peeters, Corien A
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Psychology, Clinical.

description: It has been proposed that body image is an important aspect of quality of life that has received insufficient attention in research on medical populations (Pruzinsky & Cash, 2002). The present study was designed to assess the level of body image concerns in androgen-deprived and non-androgen deprived men undergoing radiation therapy for localized prostate cancer, and a comparison group of men without cancer. The relationship between body image concerns and quality of life, and the influences of disease-specific factors, physical functioning, and cognitive investment in appearance on body image was examined. 55 men receiving androgen deprivation therapy (ADT) and radiation therapy, 41 men receiving radiation only (RT), and 56 cancer-free men (CG) completed global and disease-specific measures of body image and quality of life. Only a minority of men with localized prostate cancer (13-30%) endorsed body image concerns above normative levels. After controlling for educational status, levels of body image concerns were comparable across the three groups. Higher levels of body image distress were associated with worse quality of life scores (mental health subscale, 36-item Short-Form Medical Outcomes Study Heath Survey); however, there was no group for whom this relationship was most salient. Despite ongoing interest in quality of life outcomes associated with ADT, findings from the present study suggest that ADT (for a minimum of 3 months) does not increase risk of body image concerns during radiation treatment. However, bother associated with hormone symptoms, as well as marital status, sexual functioning, perceived physical functioning, and cognitive investment in appearance were associated with body image concerns. Findings provided preliminary support for the cognitive-behavioural model of body image disturbance in cancer patients proposed by White (2000), such that cognitive investment in appearance predicted body image concerns above and beyond demographic, medical, sexual and physical functioning variables. By focusing on men receiving radiation therapy, including a comparison group, and including a comprehensive battery of disease-specific and theoretically-based body image measures, the present study addressed some of the gaps in the previous research. Findings suggest targeting several factors amenable to counselling or behavioural interventions, such as partner support, cognitive investment in appearance, and bother associated with ADT and physical functioning, to reduce body image concerns. Whereas diverse factors were relevant to body image concerns, findings showed that a specific focus on men's perceived physical functioning, and losing weight would likely improve body satisfaction in men undergoing treatment for localized prostate cancer.
Diacylglycerol kinase zeta regulates Rac1-mediated remodeling of the actin cytoskeleton
Creators: name: Abramovici, Hanan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Biology, Neuroscience.

description: The lipid second messengers diacylglycerol (DAG) and phosphatidic acid (PA) regulate the activity and localization of actin reorganizing proteins that participate in cellular shape changes underlying important biological processes. DAG kinases (DGKs) phosphorylate DAG to yield PA, thereby attenuating the activity of DAG-activated proteins and stimulating proteins that respond to PA. Using cell biological and biochemical approaches, I explored the hypothesis that DGKzeta regulates actin cytoskeleton remodeling in mammalian cells by associating with and promoting the activity of the Rho GTPase Rac1 and the Rac1-activated kinase PAK1. I found that DGKzeta forms a complex with both proteins, and that PA from DGKzeta promotes the release of Rac1 from its inhibitor RhoGDI, triggering Rac1 activation. DGKzeta also regulates the localization and activity of PAK1. Furthermore, the ability of DGKzeta to promote Rac1 activity appears to underlie important physiological processes requiring the restructuring of the actin cytoskeleton such as cell migration, neurite outgrowth, and myoblast fusion. Localization of signaling complexes to specific cellular domains is required for complex changes in cell morphology. Because subcellular localization is critical for DGKzeta function, I investigated the molecular mechanisms underlying its targeting to different cellular compartments. I found that both PKC-mediated phosphorylation of the MARCKS domain and binding of the C-terminus to syntrophins regulate DGKzeta recruitment to the plasma membrane. Collectively, my results define a molecular mechanism that regulates the recruitment of DGKzeta to the membrane and that couples changes in DAG and PA to the activation of PAK1 and Rac1. These findings have uncovered a novel role for DGKzeta in actin cytoskeleton organization.
Stem cell differentiation study: Statistical analysis and application to microarray data
Creators: name: Li, Shenggang
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Mathematics.

description: This thesis has two main aims: (1) To develop new statistical and data mining procedures for modeling stem cell genes during the differentiation process, (2) To present biological interpretations of "sternness" genes based on time-course expression patterns and genetic networks. Stem cells have been of much interest over the past few years. Up to now, scientists have recognized many crucial features that distinguish stem cells from other types of cells: first, stem cells are capable of renewing themselves, serving as the organism's repair system. Second, they can differentiate into many types of adult cells that finally form over 200 kinds of specialized cells in the body. Given the vast information in gene expression data, it is possible to develop simple and reliable methods to investigate the differentiation of stem cells. However, very little is known about the mechanisms that characterize the genome-wide dynamic regulation of gene expression controlling stem cell differentiation. Relatively few research efforts have tackled stem cell differentiation problems using statistical procedures on time-course expression data. There is no doubt that understanding the time course of differentiation is of great significance since it should enable scientists to artificially induce stem cells to generate the appropriate intended specialized cells, such as the beating cells of the heart muscle or the insulin-producing cells of the pancreas. In this thesis, we approach the time-course differentiation of stem cells, as measured by expression data, through some new statistical and data mining procedures. Our framework can be outlined as following: (1) Develop new detection methods for differential gene expression to identify "sternness" genes that drive and repress stem cell differentiation. (2) Develop time-course expression clustering analysis techniques and apply them to stem cells. (3) Explore new efficient analyzes for generalized linear models (GLM) that can be potentially applied in gene interaction network. Validations of computational performance are based on the experimental data available from StemBase, a well-cited public collection of DNA microarray data on stem cells designed for the purpose of facilitating stem cell research. Keywords. stem cells, differentiation, embryonic stern cells (ESC), microarray, gene expression, clustering, gene regulatory network, time course, differential genes, Gene Ontology(GO), similarity measures, quasi-likelihood, mixture model
Comprehensive analysis of traumatic rupture of the aorta in road traffic crashes: incorporating epidemiological insights and K-prototype clustering
Creators: name: Ma, Zhengwei
name: Zhang, Liming
name: Qiu, Changren
name: Xu, Gang
name: Liang, Ziyang
name: Wei, Wei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: The identification of crash characteristics associated with traumatic rupture of the aorta (TRA) can significantly enhance countermeasures against TRA. Conventional epidemiological approaches struggle to adequately handle the substantial variability of traffic crash data. Consequently, this study aims to integrate conventional epidemiological analysis with data-driven cluster analysis to more comprehensively analyze TRA-related crash characteristics. A total of 350 unweighted TRA crashes were extracted from traffic crash databases including comprehensive crash details and injury descriptions. Initially, a selection was made of 11 continuous variables and 9 categorical variables, describing crash characteristics. After correlation analysis and principal component analysis were applied to the dataset, K-prototype clustering was finally conducted using 6retained categorical variables and 6 principal components derived from the continuous variables. This study found significant age and gender disparities among TRA victims, with 50% falling within the age range of 25–59 years and an overwhelming majority (62.2%) being males. Side impacts emerged as the primary cause of TRA-related crashes (37.2%), followed by collisions with off-road objects (28.6%) and head-on collisions (24.8%). Cluster analyses revealed 6 distinct clusters within the TRA-related crash dataset. These clusters were characterized by factors such as vehicle model year, curb weight, collision dynamics, and seatbelt usage, providing a deeper understanding of the heterogeneity in TRA incidents and their associated factors. Although limitations related to available data sources and factors such as accompanying injuries and vehicle weight warrant further comprehensive investigations in the future, this study contributes valuable insights into TRA analysis to enhance understanding and prevention strategies.
Precise motion with piezoelectric actuator.
Creators: name: Giurgea, Constantin.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Engineering, Mechanical.

description: The purpose of this study is to determine the displacement performance of a high accuracy-positioning device equipped with three piezo ceramic actuators. The displacement performance of each individual actuator is investigated in order to perform controlled motion over a very small range. A nanometric precision three-degrees of freedom positioner was designed and fabricated. In order to design a proper closed-loop controller, the open loop characteristics of the nanopositioner were experimentally investigated.
"A singular person": Portraits of subjectivity in the poetry and prose of Matilda Betham
Creators: name: Bailey, Elaine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Biography.
subject: Literature, English.

description: 'A Singular Person': Portraits of Subjectivity in the Poetry and Prose of Matilda Betham represents the first book-length study of Matilda Betham's literary output. A poet, biographer, and portrait artist, Betham is best remembered for her friendships with S. T. Coleridge, the Lambs, and Robert Southey. Referring to manuscript and printed material, this thesis uses feminist and New Historical critical methods to examine Betham's contribution to British Romanticism. It offers a biography of Betham and a historically contextualised analysis of her own construction of women's role in civic affairs. Betham's political affiliations, as well as the generic range of her poetic and scholarly representations of history, suggest her engagement with contemporary discussions surrounding subjectivity and self-representation. Her Biographical Dictionary participates in a construction of female identity that redefines the feminine while acknowledging the influence of preceding historians. The location and recovery of her autobiographical writings inform this examination of Betham's biographical research. The thesis argues that Betham's political views surrounding broad social representation also emerge in her exploration of the relationship between the lyrical voice and enfranchised selfhood. Betham combines her scholarly and poetic depictions of the individual enacting social change in The Lay of Marie , a historically informed metrical romance that compares to compositions by poets, both male and female, who similarly consider the demands of subjective interpretation of publicly available modes of historical discourse.
The electromagnetic correlates of gaseous dissociative anaesthesia in humans
Creators: name: Pelentritou, Antria
Publisher: name: Swinburne
Year: 2024

description: Uncovering the neural correlates of consciousness remains at the forefront of neuroscientific investigations. Anaesthesia is an ideal tool for such investigations, allowing for the controlled and reversible manipulation of the degree of consciousness. This work probed anaesthetic induced unconsciousness using the under-utilized gaseous anaesthetics Xenon and Nitrous Oxide. Electrophysiological neuroimaging techniques were used to investigate brain neurophysiology during reduced consciousness in healthy volunteers to uncover shared and disparate pathways to unconsciousness. The search for universal mechanisms of anaesthesia is expected to meaningfully contribute to understanding the mechanistic distinction between conscious and unconscious processing and thus inform clinical anaesthesia practice.
Avoided Costs of Climate Services : Lake Ice Extent (LIE) Service as an Example
Creators: name: Lehtinen, Enni
Publisher: name: Zenodo
Year: 2024
Subjects: lake ice extent
climate service
economic evaluation
avoided-cost assessment

description: Lake ice is vital for functioning of the lake ecosystems and provides multiple key ecosystem services to the Arctic societies. Climate change changes lake ice conditions which affects these ecosystems and ecosystem services provided by the lake ice. To assess changes of the lake ice in the Northern hemisphere, a climate service providing information on the lake ice extent (LIE) has been set up. The LIE service generates also other types of benefits to for example sector of hydroelectricity and recreation.

Potential of climate services has not been fully realised by stakeholders and decision-makers. Economic evaluation may support communicating their value especially in times when objectives of public economy are preferred. Moreover, impacts of small climate services can be difficult to perceive, and certain types of benefits can be challenging to observe. These benefits include avoided costs using climate services.

In this thesis avoided costs of the LIE service are estimated both quantitatively and qualitatively using avoided-cost assessment. Used data includes interview results, statistical data, and previous literature. Avoided costs the service generates comprise mainly of avoided in-situ lake ice monitoring trips and travel expenses, avoided flood and infrastructure damages, and potentially avoided injuries and mortality through improved safety. Although quantitatively assessed avoided costs are quite low, level of avoided costs using the LIE service are considerable when quantitatively and qualitatively assessed avoided costs are combined. Moreover, the benefit-cost ratio (BCR) of the avoided costs is reasonable.

Findings underline the importance of understanding benefits of climate services that are difficult to quantify. Understanding these benefits also supports justifying financing of climate services. Nonetheless, results are highly uncertain and prospective assessments are required.
Road traffic crash data in Southwestern Nigeria: a qualitative analysis of sources, contents and management methods
Creators: name: Odinfono, Jude Ubaka
name: Olawole, Moses Olaniran
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: This study qualitatively examined road traffic crash (RTC) data collection and management in southwest Nigeria, with the goal of addressing the tenets of the UN Decade of Action Plan on Road Safety’s call for an effective data system. Data on RTCs data collection in the study area was obtained through key informant interviews with five hospital accident emergency unit directors, three Federal Road Safety Commission (FRSC) Sector commanders, and three Nigeria Police Force (NPF) commissioners. Datasets were transcribed, categorized, and interpreted using content analysis, descriptive statistics, and WHO recommended minimal crash data element requirements. The study found disparate systems, a lack of synergy, and discrepancy in the various data sources in the country when compared with WHO recommendations on road traffic data collection systems, with 55% of agencies using non-standardized paper forms. The study also reveals that the minimum crash data elements recommended by WHO are not consistently captured in the NPF, FRSC, and hospital traffic crash data sources. The study suggested the use of an upgraded National Road Traffic Crash Data Management System (NRTCDMS) Data Template to unify data gathering and linkage issues, but recommends a digital version of the template.
MEDIA IN THE CONFLICT BETWEEN INTERNATIONAL DIPLOMACY AND PUBLIC OPINION: CASE STUDY OF BAN OF VISAS FOR SEVEN MUSLIM COUNTRIES
Creators: name: Shayegan, Hamed
Publisher: name: TuEngr Group
Year: 2019
Subjects: Media diplomacy
International Relations
Media on foreign policy
Political conflict
Impact of media on public opinion
US Government

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 13, 10A13M: 1-16
Integration of Power to Gas/ Power to Liquids into the ongoing transformation process
Creators: name: Adlunger, Kirsten
name: Burger, Andreas
name: Hain, Benno
name: Klaus, Thomas
name: Lange, Martin
name: Lehmann, Harry
name: Mönch, Lars
name: Osiek, Dirk
name: Proske, Christopher
name: Purr, Katja
name: Schmied, Martin
name: Vollmer, Carla
Publisher: name: My University
Year: 2016
Subjects: subject: Power-to-Gas
subject: Power to Liquid
subject: Power to Gas
subject: power to liquid
subject: alternative Kraftstoffe
subject: Regenerative Energien
subject: Regenerative Energieerzeugung
subject: Climate | Energy

description: Power to gas (PtG) is a technology for producing hydrogen and methane using electricity, while power to liquids (PtL) is an electricity-based process for the generation of liquid fuels. Jointly with other so-called power-to-x technologies PtG and PtL make it possible to provide renewable energies for all applications. This position paper assesses the role and prospects of the power-to-gas/power-to-liquids (PtG/PtL) technology in a fully renewable energy system and identifies, in particular, the challenges for integration and further development of this technology in the ongoing transformation process, which should be addressed in the next few years.
description: Power to gas (⁠PtG⁠) is a technology for producing hydrogen and methane using electricity, while power to liquids (⁠PtL⁠) is an electricity-based process for the generation of liquid fuels. Jointly with other so-called power-to-x technologies PtG and PtL make it possible to provide renewable energies for all applications. This position paper assesses the role and prospects of the power-to-gas/power-to-liquids (PtG/PtL) technology in a fully renewable energy system and identifies, in particular, the challenges for integration and further development of this technology in the ongoing transformation process, which should be addressed in the next few years.
Neue Erkenntnisse aus dem IPCC-Sonderbericht über 1,5 ˚C globale Erwärmung
Creators: name: Berger, Juliane
name: Daschkeit, Achim
name: Fee, Eric
name: Kabel, Claudia
name: Knoche, Guido
name: Mattern, Kati
name: Marty, Michael
name: Voigt, Thomas
name: Bornschein, Mathias
Publisher: name: My University
Year: 2019
Subjects: subject: Klimarahmenkonvention
subject: Emissionsminderung
subject: Anpassung an den Klimawandel
subject: Nachhaltige Entwicklung
subject: IPCC
subject: Weltklimarat
subject: UNFCCC
subject: Deutsche Klimapolitik
subject: EU-Klimapolitik
subject: SDG
subject: SDGs
subject: Sustainable Development Goals
subject: Klima | Energie

description: Der ⁠IPCC⁠-Sonderbericht über 1,5 °C globale Erwärmung (SR1.5) fasst den weltweit vorhandenen wissenschaftlichen Kenntnisstand zu den Folgen von 1,5 °C globaler Erwärmung gegenüber vorindustriellen Bedingungen und zu den mit einer solchen Erwärmung konsistenten ⁠Treibhausgas⁠-Emissionspfaden zusammen. Er untersucht Maßnahmen zur Verstärkung und Beschleunigung der Aktivitäten zur Begrenzung des mensch-gemachten Klimawandels. Ein gesondertes Kapitel geht auf Berührungspunkte zu den globalen Zielen nachhaltiger Entwicklung (SDGs) ein.In einem Webinar für die Politikberatung am 26. Oktober 2018 stellte das Umweltbundesamt ausgewählte Erkenntnisse des Sonderberichtes vor. Das Webinar zielte darauf ab, wichtige Botschaften des Berichtes im klima- und umweltpolitischen Kontext darzustellen und für die Politikgestaltung verfügbar zu machen. Dieser Bericht dokumentiert die im Webinar präsentierten Inhalte und enthält im Anhang eine konsolidierte Beantwortung der im Webinar gestellten Teilnehmerfragen.
Modellierung und Kartierung atmosphärischer Stoffeinträge und kritischer Belastungsschwellen zur kontinuierlichen Bewertung der ökosystemspezifischen Gefährdung der Biodiversität in Deutschland - PINETI (Pollutant INput and EcosysTem Impact)
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2014
Subjects: Modellierung

description: Zur Bewertung der Risiken, denen naturnahe Ökosysteme durch den Eintrag von Luftschadstoffen ausgesetzt sind, wurde in diesem Vorhaben der Critical-Load-Ansatz verwendet und auf Natura 2000 Gebiete ausgedehnt. Werden die ökosystemspezifischen Critical Load durch die ebenfalls in diesem Vorhaben ermittelten Stoffeinträgen für die Jahre 2008 und 2009 überschritten, sind die Ökosysteme durch den Eintrag von Schwefel- und Stickstoffverbindungen einem Versauerungsri-siko ausgesetzt bzw. unterliegen einer unzulässigen Eutrophierung (nur Stickstoff). Damit einher geht die Gefährdung der Biodiversität in Deutschland. Beim Schutz vor Versauerung zeigen die Maßnahmen zur Luftreinhaltung große Wirkung. So verminderte sich der Anteil an Ökosystemen, die von Überschreitung der Critical Load für Säureeinträge betroffenen sind, von ehemals über 80 Prozent in den Jahren 1980 und 1990 auf nunmehr weniger als 20 Prozent (Jahr 2009). Deut-lich geringere Entlastungen gab es beim Schutz vor Eutrophierung, wo auch im Jahr 2009 noch die Hälfte aller Ökosysteme durch Stickstoffeinträge über den Critical Load hinaus gefährdet bleibt. Zur spezifischen Bewertung der Belastung von FFH-Gebieten wurden im Vorhaben metho-dische Grundlagen entwickelt.
Quelle: Forschungsbericht
description: To evaluate the risks that natural ecosystems are exposed by deposition of air pollutants, the critical load approach has been used and extended to Natura 2000 sites in this project. If the ecosystem specific critical load is exceeded due to air pollutant depositions determined in this project for the years 2008 and 2009, ecosystems are exposed to an acidification risk by the entry of sulfur and nitrogen compounds and/or are under risk of eutrophication (nitrogen only). This is accompanied by the threat to biodiversity in Germany. In protection against acidification the measures to avoid air pollution have a great effect. Thus, the proportion of ecosystems that are affected by critical load exceedances decreased from formerly more than 80 percent in the years 1980 and 1990 to recent below 20 percent (2009). But there was significantly less progress in the protection against eutrophication, where even half of all ecosystems remain endangered in 2009 by nitrogen deposition above the critical load. For specific assessment of FFH areas methodological principles were developed in the project.
Quelle: Forschungsbericht
Transfer of ascription in a church sui iuris with particular application to the archdiocese of Alba-Iulia, Romania.
Creators: name: Nagy, Laszlo.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Religion, General.

description: Prior to the Second Vatican Council, and even in the years immediately following, there was confusion in the Church regarding the meaning of the term "rite". In many instances, the official documents used the word in the sense of a Church itself; but, in others, the term referred principally to the various ceremonies and liturgical practices. Vatican II intended to apply the expression "Particular Church" to the Churches sui iuris existing in the East (a number of which comprised many Metropolinates and eparchies), but this was not in accordance with its use in other documents where the expression referred to a diocese or the equivalent. Various compromises in vocabulary were attempted. Yet, it was only with the promulgation of the Codex canonum Ecclesiarum orientalium in 1990 that the terminology was clarified. To illustrate this point, the expression "transfer of rite" can be considered. While previously, the expression referred to a transfer of membership in a Church sui iuris, according to the 1990 legislation, the correct expression would now be "transfer of membership". The norms governing transfer of membership are examined in detail, comparing the canons of the 1983 Code of Canon Law with those of the 1990 Oriental Code. There are significant differences. Because of the vicissitudes of history affecting Romania, the Latin Archdiocese of Alba-Iulia has experienced serious difficulties in determining the status of membership of many of the faithful who often changed adherence according to the political situation. To explain this, we must recall that Transylvania was part of Hungary; later, following the two World Wars, certain parts were annexed to Romania. An overview of the various facts leading to this complicated situation and papal and curial efforts to help clarify issues relating to membership are noted. In the final chapter of the dissertation, a number of practical issues are examined, keeping in mind their eventual relevance to the Archdiocese of Alba-Iulia. However, we must recognize at times that it is not only a question of law. The personalities involved sometimes influence the way in which the law is applied. The various calls to cooperation and inter-Church activity found in official Church documents are noted, more particularly, Pope John Paul II's Apostolic Letter for the third centenary of the union of the Greek-Catholic Church of Romania with the Church of Rome, May 7, 2000. The study concludes by noting that something must be done to respect the wishes of various Catholics who, in recent times, have transferred membership for a number of reasons (not all of which are recognized as canonically valid today), but who nevertheless are living in a somewhat ambiguous situation. Some points for future clarification are noted.
Brazilian Citizens’ Opinions and Attitudes about Farm Animal Production Systems
Creators: name: Yunes, Maria C.
name: Von Keyserlingk, Marina A. G.
name: Hötzel, Maria J.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The inclusion of societal input is needed for food animal production industries to retain their “social license to operate”; failure to engage with the public on this topic risks the long-term sustainability of these industries. The primary aim of this study was to explore the beliefs and attitudes of Brazilians citizens not associated with livestock production towards farm animal production. A related secondary aim was to identify the specific beliefs and attitudes towards systems that are associated with restriction of movement. Each participant was shown pictures representing two of five possible major food animal industries (laying hens, beef cattle, pregnant sows, lactating sows, and poultry meat). Participants were presented a six pages survey that included demographic questions plus two sets of two pictures and a series of questions pertaining to the pictures. Each set of pictures represented a particular industry where one picture represented a housing type that is associated with behavioural restrictions and the other picture represented a system that allowed for a greater degree of movement. Participants were asked their perceptions on the prevalence of each system in Brazil, then their preference of one picture vs. the other, and the reasons justifying their preference. Immediately following, the participant repeated the same exercise with the second set of two pictures representing another industry followed by the same series of questions as described above. Quantitative data were analysed with mixed effects logistic regression, and qualitative responses were coded into themes. The proportion of participants that believed animals are reared in confinement varied by animal production type: 23% (beef cattle), 82% (poultry), 81% (laying hens), and 60% (swine). A large majority (79%) stated that farm animals are not well-treated in Brazil. Overall, participants preferred systems that were not associated with behavioural restriction. The preference for free-range or cage-free systems was justified based on the following reasons: naturalness, animals’ freedom to move, and ethics. A minority of participants indicated a preference for more restrictive systems, citing reasons associated with food security and food safety, increased productivity and hygiene. Our results suggest that the majority of our participants, preferred farm animal production systems that provide greater freedom of movement, which aligned with their perception that these systems are better for the animal. Our results provide some evidence that the current farm animal housing practices that are associated with restriction of movement, which are gaining traction in Brazil, may not align with societal expectations.
title: Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis
title: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels
titleType: Subtitle
Creators: name: Watzlawick, Ralf
name: Kenngott, Elisabeth E.
name: Liu, Francesca Diane M.
name: Schwab, Jan M.
name: Hamann, Alf
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Rapid activation of the innate immune system is critical for an efficient host response to invading pathogens. However, the inflammatory reaction has to be strictly controlled to minimize harmful immunopathology. A number of mediators including the cytokine interleukin-27 (IL-27) appear to be responsible for limitation and resolution of inflammation. Despite increasing knowledge of its suppressive effects on T cells, the influence on neutrophils and macrophages is poorly understood. To determine the role of IL-27 in innate immune responses we analysed the effect of IL-27 in a T cell independent model of zymosan-induced peritonitis. Early administration of recombinant IL-27 strongly reduced the number of neutrophils recruited to the peritoneal cavity after zymosan application as well as the neutrophil frequency in the blood. Simultaneously, IL-27 reduced the release of neutrophils from the bone marrow upon inflammation. Although cytokine levels were not affected by IL-27 treatment, the levels of the chemokines KC, MCP-1 and MIP-1α in the peritoneal fluid were strongly decreased. These findings demonstrate that IL-27 is able to control mobilisation and recruitment of neutrophils into the peritoneal cavity and identify a novel mechanism to limit inflammation caused by innate immune cells.
Galaxy and Mass Assembly (GAMA): Improved emission lines measurements in four representative samples at 0.07 z 0.3
Creators: name: Rodrigues, M.
name: Foster, C.
name: Taylor, Edward
name: Wright, A. H.
name: Hopkins, A. M.
name: Baldry, I.
name: Brough, S.
name: Bland-Hawthorn, J.
name: Cluver, Michelle
name: Lara-López, M. A.
name: Liske, J.
name: López-Sánchez, Á. R.
name: Pimbblet, K. A.
Publisher: name: Swinburne
Year: 2024

description: This paper presents a new catalog of emission lines based on the GAMA II data for galaxies between 0.07 9.4 at z ~ 0.1 and log M∗> 10.6 at z ~ 0.30. We have developed a dedicated code called MARVIN that automates the main steps of the data analysis, but imposes visual individual quality control of each measurement. We use this catalog to investigate how the sample selection influences the shape of the stellar mass - metallicity relation. We find that commonly used selection criteria on line detections and by AGN rejection could affect the shape and dispersion of the high-mass end of the M - Z relation. For log M∗> 10.6, common selection criteria reject about 65% of the emission-line galaxies. We also find that the relation does not evolve significantly from z = 0.07 to z = 0.34 in the range of stellar mass for which the samples are representative (log M∗> 10.6). For lower stellar masses (log M∗< 10.2) we are able to show that the observed 0.15 dex metallicity decrease in the same redshift range is a consequence of a color bias arising from selecting targets in the r-band. We highlight that this color selection bias affects all samples selected in r-band (e.g., GAMA and SDSS), even those drawn from volume-limited samples. Previously reported evolution of the M - Z relation at various redshifts may need to be revised to evaluate the effect of this selection bias.
Human biomonitoring guidance values (HBM-GVs) for priority substances under the HBM4EU initiative - new values derivation for deltamethrin and cyfluthrin and overall results
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2023
Subjects: Human-Biomonitoring
Gesundheitsgefährdung

description: The European Initiative HBM4EU aimed to further establish human biomonitoring across Europe as an important tool for determining population exposure to chemicals and as part of health-related risk assessments, thus making it applicable for policy advice. Not only should analytical methods and survey design be harmonized and quality assured, but also the evaluation of human biomonitoring data. For the health-related interpretation of the data within HBM4EU, a strategy for deriving health-based human biomonitoring guidance values (HBM-GVs) for both the general population and workers was agreed on. On this basis, HBM-GVs for exposure biomarkers of 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH), phthalates (diethyl hexyl phthalate (DEHP), di-n-butyl phthalate (DnBP), diisobutyl phthalate (DiBP), butyl benzyl phthalate (BBzP), and bis-(2-propylheptyl) phthalate (DPHP)), bisphenols A and S, pyrethroids (deltamethrin and cyfluthrin), solvents (1-methyl-2-pyrrolidone (NMP), 1-ethylpyrrolidin-2-one (NEP), N-dimethylformamide (DMF), N,N-dimethylacetamide (DMAC)), the heavy metal cadmium and the mycotoxin deoxynivalenol (DON) were developed and assigned a level of confidence. The approach to HBM-GV derivations, results, and limitations in data interpretation with special focus on the pyrethroids are presented in this paper. © 2023 The Authors
The quantification of fungal biomass and cellulase activity of Thielavia terrestris.
Creators: name: Wojtczak, Grazyna.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Biology, Botany.

description: A range of thermophilic fungi were screened for their ability to produce an effective extracellular cellulase enzyme system. Thielavia terrestris 255B was shown to be a promising organism as it produced an efficient, thermostable cellulolytic enzyme complex. The quantification of fungal growth was also studied using different biomass estimating procedures. It was apparent that fungal biomass was not directly related to cellulase production and that the latter peaked after fungal growth was completed. Although crude thermophilic enzymes can operate effectively at elevated temperatures, their activities were found to be comparable to commercial mesophilic cellulases. However, as thermophilic cellulases are much more thermostable, their half-lives are considerably longer and the enzymes can be used for prolonged reaction periods. A comparison of standard assay methods and the cellulase complexes overall hydrolytic potential was made. (Abstract shortened by UMI.)
3288021.pdf
Creators: name: Hamidfar, Tabassom
name: Tokmakov, Kirill
name: Mangan, Brian
name: Windeler, Robert
name: Dmitriev, Artemiy
name: Vitullo, Dashiell
name: Bianucci, Pablo
name: Sumetsky, Misha
Publisher: name: Optica Publishing Group
Year: 2018
Subjects: Uncategorized

description: supplementary material
Automated test system for ADSL equipment.
Creators: name: Syed, Tariq.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Engineering, Electronics and Electrical.

description: To achieve a competitive edge, reduced development cost, timely product delivery and product quality are the essential requirement for today's organization. Manual testing, requires skill workers which increases cost; increases testing time which delays product delivery; reduces number of test cases which affects product quality, is not a desirable choice. The low cost PC based automated system helps to get an edge by fulfilling the today's organization requirement. The automated testing system described in this thesis is developed to support functional testing of all testing phases of Nortel's 1-Meg Modem System (SUT). The SUT is an inherently complex ADSL product and its testing is far more complex than just verification of process faults. The complexity of ADSL system, renders automated test system an important and imperative part of ADSL testing. The requirement for an automated system has greatly increased due to the realization that manual testing is associated with additional resources and staffing constraints, which takes 15 to 90 minutes to run a single test on the SUT. Manual testing also requires additional time to perform re-execution for debugging and validation for fault correction. Whereas automation can do multiple re-execution of each test thereby increasing the amount of regression testing dramatically and improving the quality of feature testing on the SUT. This thesis shows the indispensable requirement of automated test system for ADSL testing and its advantageous of developing a competitive edge for the organization.
Roadmap for Healthy Buildings - 1st step
Creators: name: Reihlen, Antonia
name: Jepsen, Dirk
name: Rödig, Lisa
Publisher: name: My University
Year: 2018
Subjects: subject: Bauprodukt
subject: construction product
subject: EU Construction Products Regulation
subject: healthy buildings
subject: Waste | Resources

description: A harmonised documentation of emission test results of construction products is needed for the declarations of performance under the EU Construction Products Regulation. In the discussions regarding the level of information details to be provided it has been difficult to find consensus due to the conflicting interests of the various parties concerned. In the view of the German authorities a high level of protection for human health is the main aspect to be addressed by the documentation requirements. This report presents a summary of the main arguments exchanged during a parliamentarian lunch briefing in Brussels on the 19th of October 2017 on this issue.
Characterization of different CTC subpopulations in non-small cell lung cancer
Creators: name: Hanssen, Annkathrin
name: Wagner, Jenny
name: Gorges, Tobias M.
name: Taenzer, Aline
name: Uzunoglu, Faik G.
name: Driemel, Christiane
name: Stoecklein, Nikolas H.
name: Knoefel, Wolfram T.
name: Angenendt, Sebastian;
name: Hauch, Siegfried
name: Atanackovic, Djordje
name: Loges, Sonja
name: Riethdorf, Sabine
name: Pantel, Klaus
name: Wikman, Harriet
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Epithelial–mesenchymal transition
subject: Non-small-cell lung cancer
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Circulating tumour cells (CTCs) serve as valuable biomarkers. However, EpCAM positive CTCs are less frequently detected in NSCLC patients compared to other epithelial tumours. First, EpCAM protein expression was analysed in primary and metastatic lung cancer tissue. In both groups 21% of the samples were EpCAM negative. Second, the CellSearch system identified 15% of patients (n = 48) as CTC positive whereas a multiplex RT-PCR for PIK3CA, AKT2, TWIST, and ALDH1 following EGFR, HER2 and EpCAM based enrichment detected CTCs in 29% of the patients. Interestingly, 86% of CTC positive patients were found to express ALDH1. Only 11% of the patients were CTC-positive by both techniques. CTC positivity was associated with patient disease state when assessed by the multiplex RT-PCR assay (p = 0.015). Patients harbouring tumours with an altered EGFR genotype were more frequently CTC-positive compared to patients with EGFR wildtype tumours. In subsets of patients, CTCs were found to express genes involved in resistance to therapy such as HER3 and MET. In conclusion, using multiple targets for CTC capture and identification increases the sensitivity of CTC detection in NSCLC patients, which can be explained by the presence of different CTC subtypes with distinct molecular features.
Navigating Pathways to Community: Exploring the Experiences of Community-Engaged Humanities and Social Science Academics
Creators: name: Kelly, Wade
Publisher: name: Swinburne
Year: 2024

description: This research addresses how academics participate in the community. The findings explore what community engagement is and why and how it occurs, how social science and humanities academics conduct engagement activities and how they are, or are not, supported (through institutional units, colleagues, etc.), acknowledged (by superiors, colleagues, and community), and rewarded (through the promotions process). In spite of considerable institutional rhetoric proclaiming a commitment to community engagement, in many cases engagement activities are not well supported. Finally, the notion of 'societal impact' is considered, and participants reflected on how their research creates change in the communities they work with.
Analyse von Trends in der Schweizer Bankenwelt
Creators: name: (:Unkn) Unknown
Publisher: name: Hochschule für Wirtschaft FHNW
Year: 2013
Subjects: subject: Schweizer Banken
subject: Trends
subject: Regulierungen
subject: Risikoaversion
subject: Hypotheken
subject: Technologie
subject: 330 - Wirtschaft

description: Die Anforderungen an Banken aufgrund von Regulierungen, die steigende Risikoaversion der Kunden, Hypotheken im Pensionsalter und die technische Entwicklung im Bankensektor werden in dieser Bachelor Thesis untersucht und auf ihre Tauglichkeit als Trend für die kommenden fünf bis zehn Jahre bewertet.
Data for Policy 2021 information pack
Creators: name: Engin, Zeynep
name: Crowcroft, Jon
name: Verhulst, Stefaan
name: Data for Policy CIC
Publisher: name: Zenodo
Year: 2021

description: Information pack for Data for Policy 2021 "Lessons for policy-data interactions after Covid-19", held online 14-16 September 2021.
Circuit synthesis evolution using a hardware-based genetic algorithm.
Creators: name: Abielmona, Rami.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Engineering, Electronics and Electrical.

description: Genetic algorithm Synthesis (GaS) is presented in this thesis. GaS is based on a hardware implementation of a genetic algorithm (GA), aimed at evolving the logic circuit of a defined input function, while minimizing the total number of resources utilized on the underlying hardware platform. A GA bases its operation on society itself, attempting to imitate natural selection in computing systems [1]. It has been found that GAs are very good search techniques, to be used when either the search space is vast or the present deterministic techniques are too restrictive. The field of logic synthesis, as well as technology mapping onto a field-programmable gate array (FPGA), contain both of the aforementioned obstacles, and thus a new method must be realized to overcome these obstacles. GaS is the integration of a multitude of technologies, and the realization of a solution for the automated synthesis of combinational logic circuits. The work falls under the evolvable hardware (EHW) [2] domain which is a very novel field of research. The presented system is fully functional, and has been prototyped onto a computing platform, which embeds itself into a personal computer, with the main communications path being the local bus. The front-end of GaS consists of a command-line interface, whence the user inputs both the truth table representation of the Boolean function to be evolved, as well as a few initializing parameters. The system then proceeds to evolve a solution for the user's problem. Experimental results are presented in this thesis. In simple terms, the speedup factors are very promising, and in future versions of the system, the improvements that could be realized will usher in a new computing paradigm: evolvable computing.
Investigation of a surrogate measure-based safety index for predicting injury crashes at signalized intersections
Creators: name: Hasanpour, Maryam
name: Persaud, Bhagwant
name: Mansell, Robert
name: Milligan, Craig
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: The paper develops a machine learning-based safety index for classifying traffic conflicts that can be used to estimate the frequency of signalized intersection crashes, with a focus on the more severe ones that result in fatal and severe injury. The number of conflicts in different severity levels categorized by the safety index is used as an explanatory variable for developing statistical models for pro-actively estimating crashes. Video-derived conflicts in different severity levels between left-turning vehicles and opposing through vehicles, a well-recognized severe injury crash typology at signalized intersections, were identified by jointly integrating the indicators of frequency and severity, using an autoencoder neural network integration method to develop anomaly scores. Regression models were then developed to relate crashes at the same intersections to the classified conflicts based on the value of their safety indexes. Cumulative Residual plots were investigated. Finally, equations defining the boundary between consecutive anomaly score levels were developed to facilitate application in practice. Regression models for total and fatal plus severe (FSI) crashes utilizing classified extreme conflicts based on anomaly scores were found to outperform the models using total conflicts. The improvement is more pronounced for FSI crashes. The results also suggest that the machine learning integration method can efficiently classify conflicts accurately according to crash severity levels since the higher anomaly score is associated with a higher crash severity level (i.e., FSI). The proposed framework represents a methodological advancement in traffic conflict-based estimation of crashes using a machine learning model to classify conflicts by their anomaly scores. For jurisdictions without the resources to develop such a model to classify conflicts for their own datasets, the simple equations defining the boundary between consecutive anomaly score levels could be used as an approximation.