cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Disclosure and attraction : the Carnegie effect
Creators: name: Wiggins, Candace Taylor
Publisher: name: University of British Columbia
Year: 2010

description: Considerable evidence indicates that disclosing personal information tends to increase the listener's attraction to the discloser. Wiggins and Paulhus (1984) demonstrated the complementary effect -- subtly inducing a person to talk about herself increases liking for the listener (The Carnegie Effect). A study was designed to replicate their findings and examine the processes that underlie the Carnegie Effect. In addition, it was predicted that intimacy would moderate the disclosure-attraction relationship. Eighty-four female subjects were assigned to one of six cells in a 2 (talk-time: low vs. high) x 3 (topic intimacy: low, moderate or high) ANOVA design. After completing several individual difference measures, each subject participated in a 14-minute conversation with a confederate. Following the interaction, subjects completed state self-evaluation and affect measures, rated their impressions of the discussion, and rated the confederate on several liking and evaluation indexes. In general, the Carnegie Effect was confirmed: Subjects encouraged to talk about themselves expressed high global liking for the confederate, indicated a desire for future interaction with her, and rated her positively on a number of likeability items. Ratings of interestingness, however, were unaffected by the talk-time manipulation. There was no main effect for intimacy, although a number of interesting interactions emerged between that factor and the individual difference variables. Of the several intervening processes examined, inferred liking appears to be the variable that mediates the Carnegie Effect. Results are discussed in the context of the multidimensional nature of interpersonal attract ion.
An Alternative approach to regional planning : a carrying-capacity framework for achieving a viable region
Creators: name: Inoue, Yūichi
Publisher: name: University of British Columbia
Year: 2010

description: The purpose of this thesis is to develop an alternative approach to regional planning based on the concept of carrying capacity. I assume that the relationship between human society and its ecological resource base has substantially changed because of the unprecedented economic expansion subsidized by fossil fuel and consequently we can no longer behave as if the natural environment had unlimited capability to accommodate human economic activity. In this situation, in order to ensure the long-term welfare of regional residents, it is necessary to improve the viability of a region by restructuring its economy in such a way as to promote regional economic self-reliance and ensure sensible natural resource management. Efforts should be made to achieve a self-reliant economy using regional resources on a sustainable basis. The concept of carrying capacity, which is an explicit representation of limits to growth, can provide a valuable framework for these efforts. I propose a conceptual framework of carrying capacity, where four variables are incorporated. They are [1] natural capability, [2] human intervention, [3] material standard of living, and [4] interregional transfer of commodities. The exploration of this alternative approach to regional planning involves four steps. First, I examine the present nature-human relationship paying special attention to the prevailing assumption about the natural environment and the role of fossil fuel in industrial society. Second, I consider what the viability of a regional economy is and how it can be improved under the circumstances clarified in the preceding step. Third, I examine the meaning of carrying capacity criticizing the existing applications, and develop a carrying-capacity framework that can help achieve a viable region. Fourth, I describe how the proposed framework be applied to the efforts to design a mode of production and consumption that is compatible with a viable region.
Orbital current patterns in doped two-leg Cu-O Hubbard ladders
Creators: name: Chudzinski, P.
name: Gabay, M.
name: Giamarchi, T.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In the weak coupling limit, we investigate two-leg ladders with a unit cell containing both Cu and O atoms, as a function of doping. For purely repulsive interactions, using bosonization, we find significant differences with the single orbital case: a completely massless quantum critical regime is obtained for a finite range of carrier concentration. In a broad region of the phase diagram the ground state consists of a pattern of orbital currents plus a density wave. NMR properties of the Cu and O nuclei are presented for the various phases.
Different effects of single and fractionated light delivery regimes in photodynamic therapy with hypericin on HT-29 cells in vitro
Creators: name: Grada Kulikova, Lucia
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2009

description: Photodynamic therapy (PDT) is an alternative cancer cure which involves the selective uptake and retention of a photosensitizer in a cancer tissue, followed by irradiation with light of a specific wavelength to kill tumour cells via the production of reactive oxygen species (ROS). Fractionation of the light administration is one of the protocol modifications in PDT based on the hypothesis of tissue reoxygenation during the one or more dark intervals between illuminations with a subsequent greater production of singlet oxygen and thus greater PDT effect. However we demonstrate in the present study that two-fold illumination scheme with equal light doses (3 or 6 J.cm-2) separated by a dark interval 1 or 6 h do not enhanced, even reduced hypericin-mediated photocytotoxic effect in HT-29 adenocarcinoma cells in vitro by illumination with unequal light doses (1 + 11 J.cm-2) separated with a longer dark pause (6 h). Fractionation with a longer dark pause increased cell number and cell survival in HT-29 cells when compared with such treatment but with a 1 h dark pause or with a single light delivery (12 J.cm-2). Even proportion of cells in G1 and G2 phase of cell cycle were near to control. Longer dark pause also repressed cell death and enhanced clonogenic potential of HT-29 cells. Since longer dark interval after the irradiation by first sub-lethal light dose (1 J.cm-2) makes cells resistant to the effect of the lethal light dose (11 J.cm-2), we studied the events proceeded during a dark pause after sub-lethal dose (1 J.cm-2) up to the second illumination. We show that pre-sensitization did not affect physiological elimination of hypericin however administration regime affected hypericin elimination after lethal dose. Inhibition of p38 MAPK did not improve photocytotoxic effect of light fractionation. Cell pre-sensitization induced ROS production, increased activity of redox-regulated nuclear transcription factor NF-κB and expression of proteins connected with a cell survival (NF-κB p50 and p65 subunits, IκB-α, Mcl-1, HSP70, GRP94, Clusterin-α). Although the role of heat shock proteins was generally established in response upon photo-induced stress, we uncovered that HSPs are not necessarily the “key” molecules in photo-resistance. Our findings indicate that timing of the second light dose before or after NF-κB activation could be crucial for the fate of cancer cell. We estimate successful application of hypericin in a high-dose multi-fraction PDT with dark intervals reduced bellow 1 h that might yield improved outcome.
Construction of Large Constant Dimension Codes With a Prescribed Minimum Distance
Creators: name: Kohnert, Axel
name: Kurz, Sascha
Publisher: name: arXiv
Year: 2008
Subjects: subject: Information Theory (cs.IT)
subject: Discrete Mathematics (cs.DM)
subject: Combinatorics (math.CO)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: In this paper we construct constant dimension space codes with prescribed minimum distance. There is an increased interest in space codes since a paper by Koetter and Kschischang were they gave an application in network coding. There is also a connection to the theory of designs over finite fields. We will modify a method of Braun, Kerber and Laue which they used for the construction of designs over finite fields to do the construction of space codes. Using this approach we found many new constant dimension spaces codes with a larger number of codewords than previously known codes. We will finally give a table of the best found constant dimension space codes.
description: 13 pages, 1 figure, 1 table, submitted
Metal-Enhanced Fluorescence from Nanoparticulate Zinc Films
Creators: name: Aslan, Kadir
name: Previte, Michael J. R.
name: Zhang, Yongxia
name: Geddes, Chris
Publisher: name: ACS
Year: 2008

description: A detailed study of metal-enhanced fluorescence (MEF) from fluorophores in the blue-to-red spectral region placed in close proximity to thermally evaporated zinc nanostructured films is reported. The zinc nanostructured films were deposited onto glass microscope slides as individual particles and were 1?10 nm in height and 20?100 nm in width, as characterized by Atomic Force Microscopy. The surface plasmon resonance peak of the zinc nanostructured films was ?400 nm. Finite-difference time-domain calculations for single and multiple nanostructures organized in a staggered fashion on a solid support predict, as expected, that the electric fields are concentrated both around and between the nanostructures. Additionally, Mie scattering calculations show that the absorption and scattering components of the extinction spectrum are dominant in the UV and visible spectral ranges, respectively. Enhanced fluorescence emission accompanied by no significant changes in excited-state lifetimes of fluorophores with emission wavelengths in the visible blue-to-red spectral range near-to zinc nanostructured films were observed, implying that MEF from zinc nanostructured films is mostly due to an electric field enhancement effect.
Comment on ``Precision measurement of the Casimir-Lifshitz force in a fluid''
Creators: name: Geyer, B.
name: Klimchitskaya, G. L.
name: Mohideen, U.
name: Mostepanenko, V. M.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: General Physics (physics.gen-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Recently J.N. Munday and F. Capasso [Phys. Rev. A {\bf 75}, 060102(R) (2007); arXiv:0705.3793] claimed that they have performed a precision measurement of the Casimir force between a sphere and a plate coated with Au, both immersed in ethanol. The measurement results were claimed to be consistent with the Lifshitz theory. We demonstrate that the calculation of the Casimir force between the smooth bodies following the authors prescription has a discrepancy up to 25% with respect to authors result. We show also that the attractive electrostatic force only due to the surface potential differences was underestimated by a factor of 590 and the charge double layer interaction was not taken into account. All this leads to the conclusion that the results of this experiment are in fact uncertain.
description: 5 pages, 1 figure, submitted to Physical Review A; corrections are made in accordance to referee's suggestions
Additional file 1 of DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data
Creators: name: Muskovic, Walter
name: Powell, Joseph E.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 1. A document containing supplementary figures 1-8 and supplementary tables 1-3 referenced in the main text of the manuscript
title: Living Life: Young Men’s Experiences of Long-Term Imprisonment
Creators: name: Tynan, Rachel
Publisher: name: Goldsmiths, University of London
Year: 2022

description: This research is concerned with the long-term imprisonment of young men aged 15-18 and is based on fieldwork conducted at a single site in England. Using empirical, qualitative data obtained through ethnographic methods of observation, participation and interviewing, the thesis investigates how young men cope with long-term imprisonment and how they imagine their futures. Young people’s experiences of imprisonment are understood from the perspective of their own biographies, and the thesis argues that studies of youth imprisonment should incorporate this perspective.

The research also identifies the pains of imprisonment that young men describe and the function of violence within the institution and as a tool for constructing and maintaining identity prior to and during imprisonment. Young prisoners experience - and resist - the imposition of racial, class and legal status in specific ways and their resistance is what creates a unique ‘prison culture’ that is not held exclusively in the institution but travels with young people. Resistance is often realised through violence but young people’s recognition of violence is mediated through the same imposed characteristics.

The thesis advances the idea that young prisoners draw on their biographies and that this forms the basis of a carceral habitus, a set of inter-related dispositions that enable young people to navigate their sentence. This habitus is shaped by the geographical and social attributes of the institution but, more significantly, by their relationships with others inside and outside the prison. The thesis highlights that the relationship between biography and habitus is mediated through trauma and argues that the interaction between the two should not be overlooked.

Finally, the thesis sets out the need for studies of youth imprisonment to consider the wider sociological and historical factors that contribute to how imprisonment is constructed and how it is experienced by young people.
Signaling pathways and mechanism of action of the extracellular superoxide dismutase, SOD3
Creators: name: Laatikainen, Lilja Elisa
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2009

description: Reactive oxygen species (ROS) and especially hydrogen peroxide (H2O2) have been implicated in a multitude of cellular events ranging from pathogen eradication to finely tuned intracellular signal transduction under normal and pathological conditions. In some organs, such as thyroid gland, or in tissue injuries their expression is naturally high and requires special measures to keep it under control. Extracellular superoxide dismutase (SOD3) is an antioxidative enzyme, which converts superoxide into H2O2 thus reducing the harmful ROS burden of injured tissues. Recently, a more versatile role for SOD3 as an anti-inflammatory and signal modulating agent has begun to emerge. We studied the mechanism of action of SOD3 in tissue injury recovery and whether it has a role in the thyroid gland physiology and pathophysiology, which untill now have remained uncharacterized. We performed an adenovirally mediated gene transfer of SOD3 into rat hind limb and mouse peritoneum to assess its effect on tissue recovery and leukocyte migration. Our rat hind limb ischemia model provided an acute ischemic injury to study the effects of therapeutic molecules on the initiation of inflammation. A mouse peritonitis model allowed a more specific analysis of the infiltrating inflammatory cell subtypes. We also determined the expression of SOD3 and its influence on thyrocyte function from rat and human thyroid tissues and cell lines. SOD3 gene transfer markedly reduced the inflammatory cell accumulation into the rat hind limbs and the mouse peritonea as well as improved rat muscle tissue recovery. Interestingly, SOD3 seemed to have a pronounced effect on the macrophage population. Activation of the Ras-mitogen activated protein kinase (MAPK) pathway was upregulated whereas the expression of several inflammatory cytokines and cell adhesion molecules was downregulated. The SOD3 expression analysis and signal transduction studies on thyroid revealed high thyrotropin mediated SOD3 expression in normal rat thyroid and even higher in hyperproliferative goitrous tissue. Accordingly, silencing of SOD3 by small interfering RNA reduced thyrocyte proliferation. However, thyroid cancer tissue from human patients and rat thyroid cancer cell lines had significantly lower SOD3 expression. These studies describe a novel role for SOD3 in cell proliferation in injured tissue and in the thyroid gland physiology. Additionally, they elucidate the anti-inflammatory mechanism of SOD3. Thus, SOD3 could have therapeutic value in treatment of ischemic injuries, and in assessment of the degree of malignancy in thyroid hyperproliferative disorders.
Evolution of Low-Mass Helium Stars in Semidetached Binaries
Creators: name: Yungelson, L. R.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present results of a systematic investigation of the evolution of low-mass (0.35, 0.40, and 0.65 solar mass) helium donors in semidetached binaries with accretors - white dwarfs. In the initial models of evolutionary sequences abundance of helium in the center is between $\simeq 0.1$ and 0.98. Results of computations may be applied to the study of the origin and evolutionary state of AM CVn stars. It is shown that the minimum orbital periods of the systems only weakly depend on the total mass of the system and evolutionary state of the donor at RLOF and are equal to 9-11 min. The scatter in the mass-exchange rates at a given orbital period in the range between period minimum and about 40 min. does not exceed $\sim 2.5$. At orbital periods exceeding about 20 min. mass-losing stars are weakly degenerate homogeneous cooling objects and abundances of He, C, N, O, Ne in the matter lost by them depend on the extent of He-depletion at RLOF. For the systems which are currently considered as the most probable model candidates for AM CVn stars with helium donors these abundances are, approximately, Y$>$0.4, X_C$
description: 21 pages, 10 figures, to be published in Astronomy Letters, vol.34, no.9, 2008. Detailed results of computations are available at http://www.inasan.ru/~lry/HELIUM_STARS . P-logR_{He} curves in Fig. 3 corrected
Role of Leptin and metabolism in survival of autoreactive CD4+ T cells
Creators: name: Galgani, Mario
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2009

description: Recent evidence has shown that leptin, the adipose-tissue derived hormone, can influence T cell homeostasis and survival through the control of genes involved in these processes. Leptin deficient ob/ob mice and humans show reduced circulating number of T cells particularly in the CD4+ compartment. Here, we investigate in vivo how leptin controls survival and proliferation of normal and autoreactive CD4+ T cells. We have previously observed the impaired capacity of myelin-olygodendrocyte glycoprotein peptide (MOG35-55)-specific CD4+ T cells, to transfer experimental autoimmune encephalomyeleitis (EAE) in ob/ob mice. In vivo this process was associated with a progressive decline in dalyed-type hypersensitivity responses (DTH) and proliferation against the MOG35-55 peptide. Adoptive transfer experiments with pathogenic-MOG35-55-activated CD4+ T cells labeled with the fluorescent die 5-6-carboxyfluorescein succinimidylester (CFSE) into normal wild-type (WT), ob/ob and ob/ob-recombinant leptin (rleptin) treated mice, showed in ob/ob mice a reduction of the number of CFSE+CD4+ T cells at different time points as well as increased apoptosis rate and reduced Bcl-2 expression. Similar results were obtained after transferring into ob/ob mice homogeneous, antigen-specific T cells from pigeon cytochrome c (PCC) transgenic (AND-TCR) mice. Next, we explored the molecular targets possibly involved in this process and concentrated our attention on the AKT-mammalian-target of rapamycin (mTOR) signaling pathway. We observed a reduced expression of the AKT and of the downstream mTOR target, S6 ribonuclear protein (S6), in MOG35-55-specific T cells transferred into ob/ob mice. The involvement of the mTOR pathway was also confirmed by a reduced survival of the CD4+ T cells in WT mice after treatment with rapamycin and subsequent reduction in circulating leptin levels. These data highlight the role of leptin in the regulation of survival and proliferation of autoreactive T cells and link the metabolism to autoimmunity.
A Detailed Study of Gas and Star Formation in a Highly Magnified Lyman Break Galaxy at z=3.07
Creators: name: Coppin, K. E. K.
name: Swinbank, A. M.
name: Neri, R.
name: Cox, P.
name: Smail, Ian
name: Ellis, R. S.
name: Geach, J. E.
name: Siana, B.
name: Teplitz, H.
name: Dye, S.
name: Kneib, J. -P.
name: Edge, A. C.
name: Richard, J.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the detection of CO(3-2) emission from a bright, gravitationally lensed Lyman Break Galaxy, LBGJ213512.73-010143 (the 'Cosmic Eye'), at z=3.07 using the Plateau de Bure Interferometer. This is only the second detection of molecular gas emission from an LBG and yields an intrinsic molecular gas mass of (2.4+/-0.4)x10^9 Mo. The lens reconstruction of the UV morphology of the LBG indicates that it comprises two components separated by ~2 kpc. The CO emission is unresolved, and appears to be centered on the intrinsically fainter (and also less highly magnified) of the two UV components. The width of the CO line indicates a dynamical mass of (8+/-2)x10^9csc(i)^2 Mo within the central 2 kpc. Employing mid-infrared observations from Spitzer we derive a stellar mass of ~(6+/-2)x10^9 Mo and a star-formation rate of ~60 Mo/yr, indicating that the molecular gas will be consumed in ~40 Myr. The gas fractions, star-formation efficiencies and line widths suggests that LBGJ213512 is a high-redshift, gas-rich analog of a local luminous infrared galaxy. This galaxy has a similar gas-to-dynamical mass fraction as observed in the submillimeter-selected population, although the gas surface density and star-formation efficiency is a factor of 3x less, suggesting less vigorous activity. We discuss the uncertainties in our conclusions arising from adopting a CO-to-H2 conversion factor appropriate for either the Milky Way or local luminous infrared galaxies. These observations demonstrate that current facilities, when aided by fortuitous gravitational magnification, can study 'ordinary' galaxies at high-redshift and so act as pathfinders for ALMA.
description: 8 pages, 3 figures, accepted for publication in ApJ
Human-Centric Resource Allocation for the Metaverse With Multiaccess Edge Computing
Creators: name: Long, Zijian
name: Dong, Haiwei
name: Saddik, Abdulmotaleb El
Publisher: name: arXiv
Year: 2023
Subjects: subject: Multimedia (cs.MM)
subject: Artificial Intelligence (cs.AI)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Multi-access edge computing (MEC) is a promising solution to the computation-intensive, low-latency rendering tasks of the metaverse. However, how to optimally allocate limited communication and computation resources at the edge to a large number of users in the metaverse is quite challenging. In this paper, we propose an adaptive edge resource allocation method based on multi-agent soft actor-critic with graph convolutional networks (SAC-GCN). Specifically, SAC-GCN models the multi-user metaverse environment as a graph where each agent is denoted by a node. Each agent learns the interplay between agents by graph convolutional networks with self-attention mechanism to further determine the resource usage for one user in the metaverse. The effectiveness of SAC-GCN is demonstrated through the analysis of user experience, balance of resource allocation, and resource utilization rate by taking a virtual city park metaverse as an example. Experimental results indicate that SAC-GCN outperforms other resource allocation methods in improving overall user experience, balancing resource allocation, and increasing resource utilization rate by at least 27%, 11%, and 8%, respectively.
STRUTTURE CRISTALLINE DI POLIMERI DERIVANTI DA MONOMERI DIENICI. INFLUENZA DEI DIFETTI COSTITUZIONALI E CONFIGURAZIONALI
Creators: name: Giusto, Giovangiuseppe
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2008

description: In questa tesi di dottorato di ricerca sono state studiate le strutture cristalline di polimeri stereoregolari derivanti dalla polimerizzazione di monomeri dienici, quali il butadiene e i suoi derivati alchil sostituiti. In particolare tale studio è stato rivolto alla comprensione dell’influenza della sostituzione di uno o più atomi di idrogeno del 1,3-butadiene con gruppi alchilici sulla struttura cristallina e sul polimorfismo. Tale studio è stato condotto mediante l'uso congiunto della diffrazione dei raggi X e tecniche teoriche della meccanica molecolare per il calcolo dell’energia conformazionale e dell’energia di impacchettamento. È stato studiato l’impacchettamento del 1,2-poli(1,3-butadiene) sindiotattico, in particolare sono stati studiati folds con rientro adiacente. I risultati dell’analisi di impacchettamento hanno indicato che la crescita del cristallo in questo polimero avviene preferibilmente lungo la direzione 100 e che i folds costituiti da quattro unità monomeriche sono energeticamente favoriti. Il lavoro di fold calcolato dai nostri modelli è risultato in ottimo accordo con i dati sperimentali riportati in letteratura. È stata determinata la struttura cristallina del 1,2-poli(E-3-metil-1.3-pentadiene) sindiotattico e del 1,4-cis-poli(1,3-esadiene) isotattico, ottenendo un ottimo accordo con i dati sperimentali. Questo è stato possibile anche grazie ad opportune assunzioni di simmetria basate su analogie con polimeri aventi simile costituzione e configurazione e grazie alla disponibilità di un discreto set di funzioni di potenziale. Del 1,2-poli(E-3-metil-1,3-pentadiene) sindiotattico è stata considerata anche la presenza difetti di stereoregolarità. Sempre la meccanica molecolare ci ha permesso di studiare l’influenza che ha la sostituzione di uno o più atomi di idrogeno del 1,3-butadiene con gruppi alchilici. Tale studio ci ha permesso di capire che gruppi alchilici poco ingombranti provoca generalmente, sia nelle poliolefine che nei polidieni, variazioni delle dimensioni delle celle elementari lasciando inalterate le conformazioni delle catene e i gruppi spaziali. Contrariamente gruppi alchilici molto ingombranti hanno un’influenza destabilizzante sulla conformazione della catena e sul suo impacchettamento, impedendo completamente la cristallizzazione.
title: [Gesuch um Errichtung einer zweiten Postannahmestelle zu Marburg (Hessen)]
Creators: name: Müller, Ludwig
Publisher: name: Philipps-Universität Marburg
Year: 1891
Subjects: Marburg
Generalities
Allgemeines, Wissenschaft
Hassiaca

description: Elektronische Reproduktion von:[Gesuch um Errichtung einer zweiten Postannahmestelle zu Marburg (Hessen)]. Plan der Stadt Marburg / entw. von L. Müller. - [Marburg], 1891. - [3] Bl. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: 085 4 2017/01316. - Bemerkungen: (Hassiaca) Digitalisiert 2021
Plasmonic engineering of singlet oxygen generation
Creators: name: Zhang, Yongxia
name: Aslan, Kadir
name: Previte, Michael J. R.
name: Geddes, Chris
Publisher: name: PNAS
Year: 2008

description: In this article, we report metal-enhanced singlet oxygen generation (ME1O2). We demonstrate a direct relationship between the singlet oxygen yield of a common photosensitizer (Rose Bengal) and the theoretical electric field enhancement or enhanced absorption of the photosensitizer in proximity to metallic nanoparticles. Using a series of photosensitizers, sandwiched between silver island films (SiFs), we report that the extent of singlet oxygen enhancement is inversely proportional to the free space singlet oxygen quantum yield. By modifying plasmon coupling parameters, such as nanoparticle size and shape, fluorophore/particle distance, and the excitation wavelength of the coupling photosensitizer, we can readily tune singlet oxygen yields for applications in singlet oxygen-based clinical therapy.
Optimal quantum estimation in spin systems at criticality
Creators: name: Invernizzi, Carmen
name: Korbman, Michael
name: Venuti, Lorenzo Campos
name: Paris, Matteo G. A
Publisher: name: arXiv
Year: 2008
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is a general fact that the coupling constant of an interacting many-body Hamiltonian do not correspond to any observable and one has to infer its value by an indirect measurement. For this purpose, quantum systems at criticality can be considered as a resource to improve the ultimate quantum limits to precision of the estimation procedure. In this paper, we consider the one-dimensional quantum Ising model as a paradigmatic example of many-body system exhibiting criticality, and derive the optimal quantum estimator of the coupling constant varying size and temperature. We find the optimal external field, which maximizes the quantum Fisher information of the coupling constant, both for few spins and in the thermodynamic limit, and show that at the critical point a precision improvement of order $L$ is achieved. We also show that the measurement of the total magnetization provides optimal estimation for couplings larger than a threshold value, which itself decreases with temperature.
description: 8 pages, 4 figures
Additional file 2 of DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data
Creators: name: Muskovic, Walter
name: Powell, Joseph E.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 2. Review history
"Star di casa in città come in giardino”: figure e misure dell’abitabilità negli spazi domestici
Creators: name: Colace, Valentina
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2006

description: La tesi assume l’abitabilità come principio di analisi e di progettazione della casa urbana. Attraverso una lettura comparata di alcuni passi più significativi (trattati, manuali, regolamenti) e di alcune immagini più rappresentative (quadri, architetture, città), emerge con chiarezza la qualità dello spazio domestico nella casa abitabile tra vicini in logge e giardini. Il “progetto” di simulazione e verifica dei principi assunti, si traduce in realtà nel rendere esplicito il gioco di variazioni che permette di rifare il disegno dell’isolato di Nea-polis per quello che è: un “capriccio” con rovine “abitabili” in cortile.
Hardware-Aware DNN Compression via Diverse Pruning and Mixed-Precision Quantization
Creators: name: Balaskas, Konstantinos
name: Karatzas, Andreas
name: Sad, Christos
name: Siozios, Kostas
name: Anagnostopoulos, Iraklis
name: Zervakis, Georgios
name: Henkel, Jörg
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Deep Neural Networks (DNNs) have shown significant advantages in a wide variety of domains. However, DNNs are becoming computationally intensive and energy hungry at an exponential pace, while at the same time, there is a vast demand for running sophisticated DNN-based services on resource constrained embedded devices. In this paper, we target energy-efficient inference on embedded DNN accelerators. To that end, we propose an automated framework to compress DNNs in a hardware-aware manner by jointly employing pruning and quantization. We explore, for the first time, per-layer fine- and coarse-grained pruning, in the same DNN architecture, in addition to low bit-width mixed-precision quantization for weights and activations. Reinforcement Learning (RL) is used to explore the associated design space and identify the pruning-quantization configuration so that the energy consumption is minimized whilst the prediction accuracy loss is retained at acceptable levels. Using our novel composite RL agent we are able to extract energy-efficient solutions without requiring retraining and/or fine tuning. Our extensive experimental evaluation over widely used DNNs and the CIFAR-10/100 and ImageNet datasets demonstrates that our framework achieves $39\%$ average energy reduction for $1.7\%$ average accuracy loss and outperforms significantly the state-of-the-art approaches.
description: 14 pages, 9 figures
Metal-enhanced excimer (P-type) fluorescence
Creators: name: Zhang, Yongxia
name: Aslan, Kadir
name: Previte, Michael J. R.
name: Geddes, Chris
Publisher: name: Elsevier
Year: 2008

description: In this Letter, we report the first observation of metal-enhanced excimer (P-type) fluorescence from pyrene. Pyrene in close proximity to silver island films (SIFs) shows enhanced pyrene excimer emission with a ?2.5-fold higher emission intensity observed from SIFs and 5×10?3M pyrene, as compared to a quartz control sample containing no silver nanoparticles. Our findings suggest two complementary methods for the enhancement: (i) surface plasmons can radiate coupled monomer and excimer fluorescence efficiently, and (ii) enhanced absorption (enhanced electric field) further facilitates enhanced emission. This observation is helpful in our laboratory’s continued goal to develop a unified plasmon–luminophore description.
Additional file 1 of 25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
Creators: name: Yang, Limin
name: Sato, Miori
name: Saito-Abe, Mayako
name: Irahara, Makoto
name: Nishizato, Minaho
name: Sasaki, Hatoko
name: Konishi, Mizuho
name: Ishitsuka, Kazue
name: Mezawa, Hidetoshi
name: Yamamoto-Hanada, Kiwako
name: Ohya, Yukihiro
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biotechnology
Science Policy
Computational Biology

description: Additional file 1:.
Improved Measurement of Time-Dependent CP Asymmetries and the CP-Odd Fraction in the Decay B0->D*+D*-
Creators: name: BaBar Collaboration
name: Aubert, B.
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present an updated measurement of the CP-odd fraction and the time-dependent CP asymmetries in the decay B0->D*+D*-using (383 +/- 4) \times 10^{6} BB pairs collected with the Babar detector. We determine the CP-odd fraction to be $0.143\pm0.034\stat\pm0.008\syst$. The time-dependent CP asymmetry parameters are determined to be $C_+ = -0.05\pm 0.14\stat \pm 0.02\syst$ and $S_+ = -0.72 \pm 0.19\stat \pm 0.05\syst$. The non-zero value of the measured $S_+$ indicates the evidence of CP violation at the $3.7 σ$ confidence level.
description: Minor changes of the text and reference for the publication
Pyridine nucleotide transhydrogenase of Escherichia coli: nucleotide sequence of the pnt gene and characterization of the enzyme complex
Creators: name: Clarke, David Morgan
Publisher: name: University of British Columbia
Year: 2010

description: Based on the rationale that Escherichia coli cells harboring plasmids containing the pnt gene would contain elevated levels of enzyme, three clones were isolated bearing the transhydrogenase gene from the Clarke and Carbon colony bank. The three plasmids were subjected to restriction endonuclease analysis. A 10.4-kilobase restriction fragment which overlapped all three plasmids was cloned into pUC13. Examination of several deletion derivatives of the resulting plasmids and subsequent treatment with exonuclease BAL31 revealed that enhanced transhydrogenase expression was localized within a 3.05-kilobase segment. This segment was located at 35.4 min in the E. coli genome. Plasmid pDC21 conferred on its host 70-fold overproduction of transhydrogenase. The protein products of plasmids carrying the pnt gene were examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis of membranes from cells containing the plasmids and by in vitro transcription/translation of pDC21. Two polypeptides of molecular weights 52,000 and 48,000 were coded by the 3.05-kilobase fragment of pDC21. Both polypeptides were required for expression of transhydrogenase activity. The transhydrogenase was purified from cytoplasmic membranes of E. coli by pre-extraction of the membranes with sodium cholate and Triton X-100, solubilization of the enzyme with sodium deoxycholate in the presence of 1 M potassium chloride, and centrifugation through a 1.1 M sucrose solution. The purified enzyme consists of two subunits, α and β, of molecular weights 52,000 and 48,000. During transhydrogenation between NADPH and 3-acetylpyridine adenine dinucleotide by both the purified enzyme reconstituted into liposomes and the membrane-bound enzyme, a pH gradient is established across the membrane as indicated by the quenching of fluorescence of 9-aminoacridine. It was concluded that E. coli transhydrogenase acts as a proton pump which is regulated primarily by a pH gradient rather than a membrane potential. Treatment of transhydrogenase with N,N'-dicyclohexylcarbodiimide results in an inhibition of proton pump activity and transhydrogenation, suggesting that proton translocation and catalytic activities are obligatorily linked. [¹⁴C]Dicyclohexylcarbodiimide preferentially labelled the a subunit. The transhydrogenase-catalyzed reduction of 3-acetylpyridine adenine dinucleotide by NADPH was stimulated over three-fold by NADH. It was concluded that NADH binds to an allosteric binding site on the enzyme. The nucleotide sequences of the pntA and pntB genes, coding for the transhydrogenase αand β subunits respectively, were established. The molecular masses of 53,906 (α) and 48,667 (β) and the N-terminal sequences of the predicted polypeptides agree well with the data obtained by analysis of the purified subunits. Several hydrophobic regions large enough to span the cytoplasmic membrane were observed for each subunit.
Angular-dependent metal-enhanced fluorescence from silver island films
Creators: name: Aslan, Kadir
name: Malyn, Stuart N.
name: Geddes, Chris
Publisher: name: Elsevier
Year: 2008

description: In this Letter we report the observation of angular-dependent metal-enhanced fluorescence (MEF) from fluorophores deposited onto silver island films (SiFs). When illuminated with laser light (473nm) at angles of 45° and 90° from the surface, SiFs scattered light at wide observation angles biased by the direction of the incident light. We observed angular-dependent MEF (10-fold) from FITC-HSA immobilized onto the SiFs, again slightly biased with respect to the direction of the incident light. We also measured the photostability of FITC from the back of the glass substrate at angles of 225° and 340°.
Additional file 2 of 25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
Creators: name: Yang, Limin
name: Sato, Miori
name: Saito-Abe, Mayako
name: Irahara, Makoto
name: Nishizato, Minaho
name: Sasaki, Hatoko
name: Konishi, Mizuho
name: Ishitsuka, Kazue
name: Mezawa, Hidetoshi
name: Yamamoto-Hanada, Kiwako
name: Ohya, Yukihiro
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biotechnology
Science Policy
Computational Biology

description: Additional file 2:.
Normalized Augmented Inverse Probability Weighting with Neural Network Predictions
Creators: name: Rostami, Mehdi
name: Saarela, Olli
Publisher: name: arXiv
Year: 2021
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: Computation (stat.CO)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The estimation of Average Treatment Effect (ATE) as a causal parameter is carried out in two steps, where in the first step, the treatment and outcome are modeled to incorporate the potential confounders, and in the second step, the predictions are inserted into the ATE estimators such as the Augmented Inverse Probability Weighting (AIPW) estimator. Due to the concerns regarding the nonlinear or unknown relationships between confounders and the treatment and outcome, there has been an interest in applying non-parametric methods such as Machine Learning (ML) algorithms instead. Some literature proposes to use two separate Neural Networks (NNs) where there's no regularization on the network's parameters except the Stochastic Gradient Descent (SGD) in the NN's optimization. Our simulations indicate that the AIPW estimator suffers extensively if no regularization is utilized. We propose the normalization of AIPW (referred to as nAIPW) which can be helpful in some scenarios. nAIPW, provably, has the same properties as AIPW, that is, the double-robustness and orthogonality properties. Further, if the first step algorithms converge fast enough, under regulatory conditions, nAIPW will be asymptotically normal. We also compare the performance of AIPW and nAIPW in terms of the bias and variance when small to moderate L1 regularization is imposed on the NNs.
Additional file 1 of Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017
Creators: name: Maquilón, César
name: Antolini, Mónica
name: Valdés, Nicolás
name: Andrade, Marianela
name: Canales, Krishnna
name: Rabec, Claudio
name: Olave, Cristian
name: Aguayo, Miguel
name: Rivas, Patricia
name: Andrade, Carmen
name: Venegas, Ángela
name: Zapata, Sandra
name: Torres, María Elena
name: Cabrera, Osvaldo
name: Villalobos, Jorge
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Technical standard for HMV programs. Ministry of Health, versions 2008, 2012 and 2013, Chile.doc.
Agostino e il problema del male. Dal Manicheismo alle Confessioni
Creators: name: Di Silva, Maurizio Filippo
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2010

description: Il presente lavoro delinea la desostanzializzazione del negativo agostiniana. L'analisi evidenzia l'identità di male e nulla tematizzando la crisi della sostanzializzazione del male manichea, la natura del peccato e il suo nesso con l'ordine e la nozione agostiniana di corruzione. Nell'identità del non essere e del negativo emerge la natura della desostanzializzazione del male agostiniana
Physico-chemical characterization of the interaction between thyroid transcription factor 1 (TTF-1) and DNA
Creators: name: Carullo, Paola
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2010

description: The thyroid transcription factor 1 (TTF-1) is a tissue-specific transcription factor involved in the development of thyroid and lung. It is a protein of 371 amino acids that possesses two independent transcriptional activation domains, one located in the N-terminal region of homeodomain and the other in the C-terminal region. The homeodomain is a highly conserved DNA-binding motif that is found in numerous transcription factors throughout a large variety of species from yeasts to human. These gene-specific transcription factors play critical roles in development and adult homeostasis, and therefore, any germline mutations associated with these proteins can lead to a number of congenital abnormalities. Remarkable features of structural and functional conservation have been observed within homeodomain family members. This high degree of conservation between the sequence and structure makes the homeodomain an ideal model for studying protein-DNA interactions and gene regulation. In this PhD thesis, the study on the conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain (TTF-1HD) is reported. Furthermore, to gain a molecular-level understanding of the interactions determining the association of TTF-1HD to the target DNA sequence, Some key point mutants (W48, Q50 and Y54) and a deletion mutant (desTTF-1HD), lacking five residues from the N-terminal region have been produced and studied. Since it has been demonstrated that N-terminal region of TTF-1 also interact with Pax-8 (transcription factor belonging to the PAX genes superfamily) in the regulation of thyroid-specific gene expression, the study of the thermal stability and DNA binding energetics of a fusion protein, containing the N-terminal region and the homeodomain of TTF-1 (TTF-1NH2HD), and a recombinant protein containing C-terminal region of Pax-8 (Pax-8 Prd) has been reported.
Electronic and magnetic properties of a quasi-one-dimensional spin chain system, Sr$_{3}$NiRhO$_{6}$
Creators: name: Pandey, S. K.
name: Maiti, Kalobaran
Publisher: name: arXiv
Year: 2008
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate the electronic structure of Sr$_3$NiRhO$_6$, a quasi-one-dimensional spin chain system using \emph{ab initio} band structure calculations. Spin polarized calculations within GGA reveal that Ni and Rh have finite moments and they are antiferromagnetically coupled along the chain axis in the ground state. While these results obtained within the local spin density approximations provide remarkable representation of the magnetic phase, the experimentally observed insulating behavior could not be captured within this method. GGA+$U$ calculations show that opening up of an insulating gap requires on-site Coulomb interaction among the Rh 4$d$ electrons, $U_{dd}^{Rh}$ $\approx$ 2.5 eV and the correlation among Ni 3$d$ electrons, $U_{dd}^{Ni}$ $\approx$ 4.5 eV suggesting this system to be a Mott insulator. Electron correlation among $d$ electrons leads to significant enhancement of the O 2$p$ character in the energy bands in the vicinity of the Fermi level and the $d$ bands appear at lower energies. Energy gap in the up spin density of states appears to be significantly small ($\sim$ 0.12 eV) while it is $>$ 2 eV in the down spin density of states suggesting possibility of spin polarized conduction in the semiconducting phase.
description: 7 pages, 7 figures and 1 table
Questioning the Questioning Skills of Preservice Elementary Teachers
Creators: name: Yang, Shuling
name: Mickey, Diane
name: Appleget, Carin
Publisher: name: East Tennessee State University
Year: 2022

description: The literacy educators collaboratively designed an interactive read-aloud assignment to explore elementary preservice teachers’ (PSTs) questioning skills. Following the Gradual Release of Responsibility framework, the PSTs worked with small groups and whole group to complete indepth analysis of their conversations before, during, and after the read aloud with the elementary students. Overall, the PSTs’ reflections indicated that this read-aloud assignment highlighted the complexity of questioning in ways they had not previously considered and they valued the opportunities to refine their questioning skills in authentic settings. We came to the conclusion that PSTs need explicit instruction on questioning.