cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Standard Model CP-violation and Baryon asymmetry Part II: Finite Temperature
Creators: name: Gavela, M. B.
name: Hernandez, P.
name: Orloff, J.
name: Pène, O.
name: Quimbay, C.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We consider the scattering of quasi-particles off the boundary created during a first order electroweak phase transition. Spatial coherence is lost due to the quasi-quark damping rate, and we show that reflection on the boundary is suppressed, even at tree-level. Simply on CP considerations, we argue against electroweak baryogenesis in the Standard Model via the charge transport mechanism. A CP asymmetry is produced in the reflection properties of quarks and antiquarks hitting the phase boundary. An effect is present at order $α_W^2$ in rate and a regular GIM behaviour is found, which can be expressed in terms of two unitarity triangles. A crucial role is played by the damping rate of quasi-particles in a hot plasma, which is a relevant scale together with $M_W$ and the temperature. The effect is many orders of magnitude below what observation requires.
description: 44 pages, CERN-TH.7263/94, LPTHE Orsay-94/49, HUTP-94/A015, HD-THEP-94-20, FTUAM-94/14, NSF-ITP-94-65
MOESM6 of Understanding the potential bias of variance components estimators when using genomic models
Creators: name: Cuyabano, Beatriz
name: A. Sørensen
name: Sørensen, Peter
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 6. Comparison of $${\mathbf{G}}$$ G to $${\mathbf{G}}_{{\rm Q}}$$ G Q for 2000 completely unrelated individuals by: (1) direct comparison of values, (2) comparison of eigen-values ( $$\lambda_{{\rm i}}$$ λ i ), and (3) comparison of $$\lambda_{{\rm i}}$$ λ i to $$\kappa_{{\rm i}}$$ κ i , and comparison of $$\hat{\hbox{h}}^{2}_{{\rm REML}}$$ h ^ REML 2 to $$\hbox{h}^{2}$$ h 2 simulated with parameter 0.25,0.5,0.75, for 100 replicates of each simulation parameter. $${\mathbf{G}}_{{\rm Q}}$$ G Q consisted of 3000 QTL and $${\mathbf{G}}$$ G consisted of 3000 markers in complete LE with the QTL, such that $$\hbox{f}_{{\rm MAF}_{_{{\rm QTL}}}} \neq \hbox{f}_{{\rm MAF}_{_{{\rm markers}}}}$$ f MAF QTL ≠ f MAF markers .
MOESM5 of Understanding the potential bias of variance components estimators when using genomic models
Creators: name: Cuyabano, Beatriz
name: A. Sørensen
name: Sørensen, Peter
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 5. Comparison of $${\mathbf{G}}$$ G to $${\mathbf{G}}_{{\rm Q}}$$ G Q for 2000 completely unrelated individuals by: (1) direct comparison of values, (2) comparison of eigen-values ( $$\lambda_{{\rm i}}$$ λ i ), and (3) comparison of $$\lambda_{{\rm i}}$$ λ i to $$\kappa_{{\rm i}}$$ κ i , and comparison of $$\hat{\hbox{h}}^{2}_{{\rm REML}}$$ h ^ REML 2 to $$\hbox{h}^{2}$$ h 2 simulated with parameter 0.25,0.5,0.75, for 100 replicates of each simulation parameter. $${\mathbf{G}}_{{\rm Q}}$$ G Q consisted of 100 QTL and $${\mathbf{G}}$$ G consisted of these 100 QTL plus 1900 markers in complete LE with the QTL, such that $$\hbox{f}_{{\rm MAF}_{_{{\rm QTL}}}} \neq {\rm f}_{{\rm MAF}_{_{{\rm markers}}}}$$ f MAF QTL ≠ f MAF markers .
Additional file 7 of Prognostic perspectives of PD-L1 combined with tumor-infiltrating lymphocytes, Epstein-Barr virus, and microsatellite instability in gastric carcinomas
Creators: name: Choi, Euno
name: Chang, Mee Soo
name: Byeon, Sun-ju
name: Jin, Heejin
name: Jung, Kyeong Cheon
name: Kim, Haeryoung
name: Lee, Kook Lae
name: Kim, Won
name: Park, Jin Hyun
name: Kim, Ki Hwan
name: Kim, Jin-Soo
name: Choi, In Sil
name: Han, Dong-Seok
name: Ahn, Hye Seong
name: Heo, Seung Chul
Publisher: name: figshare
Year: 2020
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 7: Supplemental Table 2. Univariate and Multivariate Analyses in the Entire Cohort (N = 514) (corresponding to Fig. 2a, b & e)
HII Galaxies as deep cosmological probes
Creators: name: Melnick, Jorge
name: Terlevich, Roberto
name: Terlevich, Elena
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We re-investigated the use of the Hubble diagram to measure the cosmological constant ($Λ$) and the mass density of the Universe ($Ω_M$). We find an important focusing effect in $Λ$ for redshifts about 3. This effect implies that the apparent magnitude of a standard candle at redshifts z=2-3 has almost no dependence on $Λ$ for $Ω_M>0.2$. This means that $Ω_M$ can be measured independently of $Ω_Λ$ by targeting the redshift range according to an estimate of the value of $Ω_M$. We explore the evidence in support of the suggestion that extreme starburst galaxies also known as HII galaxies can be used as distance estimators over a wide range of redshifts and reaching very high values. We have compiled literature data of HII galaxies up to $z\sim 3$ and found a good correlation between their luminosity and velocity dispersion measured from their strong emission lines, thus confirming the correlation already known to exist for HII galaxies in the nearby Universe. Several systematic effects such as age, extinction, kinematics, and metallicity are discussed as well as the effects of different cosmologies.
description: To appear in MNRAS, 7 pages, 6 figures
Effects of a strong magnetic field on internal gravity waves: trapping, phase mixing, reflection and dynamical chaos
Creators: name: Loi, Shyeh Tjing
name: Papaloizou, John C. B.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The spectrum of oscillation modes of a star provides information not only about its material properties (e.g. mean density), but also its symmetries. Spherical symmetry can be broken by rotation and/or magnetic fields. It has been postulated that strong magnetic fields in the cores of some red giants are responsible for their anomalously weak dipole mode amplitudes (the "dipole dichotomy" problem), but a detailed understanding of how gravity waves interact with strong fields is thus far lacking. In this work, we attack the problem through a variety of analytical and numerical techniques, applied to a localised region centred on a null line of a confined axisymmetric magnetic field which is approximated as being cylindrically symmetric. We uncover a rich variety of phenomena that manifest when the field strength exceeds a critical value, beyond which the symmetry is drastically broken by the Lorentz force. When this threshold is reached, the spatial structure of the g-modes becomes heavily altered. The dynamics of wave packet propagation transitions from regular to chaotic, which is expected to fundamentally change the organisation of the mode spectrum. In addition, depending on their frequency and the orientation of field lines with respect to the stratification, waves impinging on different parts of the magnetised region are found to undergo either reflection or trapping. Trapping regions provide an avenue for energy loss through Alfven wave phase mixing. Our results may find application in various astrophysical contexts, including the dipole dichotomy problem, the solar interior, and compact star oscillations.
description: 22 pages, 15 figures, accepted for publication in MNRAS
Genetic stratification of depression in UK Biobank
Creators: name: Wray N.R
name: Adams M.J
name: McIntosh A.M
name: Coleman J.R.I
name: Sullivan P.F
name: Glanville K
name: Hagenaars S.P
name: Lewis C.M
name: Werge T
name: Breen G
name: Porteous D
name: Howard D.M
name: Han B
name: Clarke T.-K
name: Campbell A
name: Folkersen L
Publisher: name: Springer Nature
Year: 2020

description: Depression is a common and clinically heterogeneous mental health disorder that is frequently comorbid with other diseases and conditions. Stratification of depression may align sub-diagnoses more closely with their underling aetiology and provide more tractable targets for research and effective treatment. In the current study, we investigated whether genetic data could be used to identify subgroups within people with depression using the UK Biobank. Examination of cross-locus correlations were used to test for evidence of subgroups using genetic data from seven other complex traits and disorders that were genetically correlated with depression and had sufficient power (>0.6) for detection. We found no evidence for subgroups within depression for schizophrenia, bipolar disorder, attention deficit/hyperactivity disorder, autism spectrum disorder, anorexia nervosa, inflammatory bowel disease or obesity. This suggests that for these traits, genetic correlations with depression were driven by pleiotropic genetic variants carried by everyone rather than by a specific subgroup.
Triviality, perturbation theory and $Z\to b \overline b$
Creators: name: Aoki, Kenichiro
name: Peris, Santiago
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We compute the large-$m_t$ contributions to the $Zb\overline b$ vertex in the Standard Model non-perturbatively using both the $1/\nc$ and the $1/\nf$ expansions. Triviality and its consequences for the perturbative result are systematically analyzed. In particular, we point out that the effect of triviality is already important at the two-loop level for a heavy Higgs ($600\gev
description: 12pages (incl. figs.), TIT/HEP--258,CERN-TH.7287/94
ZFIRE: 3D Modeling of Rotation, Dispersion, and Angular Momentum of Star-Forming Galaxies at z~2
Creators: name: Alcorn, Leo Y.
name: Tran, Kim-Vy
name: Glazebrook, Karl
name: Straatman, Caroline M.
name: Cowley, Michael
name: Forrest, Ben
name: Kacprzak, Glenn G.
name: Kewley, Lisa J.
name: Labbé, Ivo
name: Nanayakkara, Themiya
name: Spitler, Lee R.
name: Tomczak, Adam
name: Yuan, Tiantian
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We perform a kinematic and morphological analysis of 44 star-forming galaxies at $z\sim2$ in the COSMOS legacy field using near-infrared spectroscopy from Keck/MOSFIRE and F160W imaging from CANDELS/3D-HST as part of the ZFIRE survey. Our sample consists of cluster and field galaxies from $2.0 < z < 2.5$ with K band multi-object slit spectroscopic measurements of their H$α$ emission lines. H$α$ rotational velocities and gas velocity dispersions are measured using the Heidelberg Emission Line Algorithm (HELA), which compares directly to simulated 3D data-cubes. Using a suite of simulated emission lines, we determine that HELA reliably recovers input S$_{0.5}$ and angular momentum at small offsets, but $V_{2.2}/σ_g$ values are offset and highly scattered. We examine the role of regular and irregular morphology in the stellar mass kinematic scaling relations, deriving the kinematic measurement S$_{0.5}$, and finding $\log(S_{0.5}) = (0.38\pm0.07)\log(M/M_{\odot}-10) + (2.04\pm0.03)$ with no significant offset between morphological populations and similar levels of scatter ($\sim0.16$ dex). Additionally, we identify a correlation between M$_{\star}$ and $V_{2.2}/σ_g$ for the total sample, showing an increasing level of rotation dominance with increasing M$_{\star}$, and a high level of scatter for both regular and irregular galaxies. We estimate the specific angular momenta ($j_{disk}$) of these galaxies and find a slope of $0.36\pm0.12$, shallower than predicted without mass-dependent disk growth, but this result is possibly due to measurement uncertainty at M$_{\star}$ $
description: Accepted to ApJ
Additional file 1: of CLOUD: a non-parametric detection test for microbiome outliers
Creators: name: Montassier, Emmanuel
name: Al-Ghalith, Gabriel
name: Hillmann, Benjamin
name: Viskocil, Kimberly
name: Kabage, Amanda
name: McKinlay, Christopher
name: Sadowsky, Michael
name: Khoruts, Alexander
name: Knights, Dan
Publisher: name: figshare
Year: 2018
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: R code for calculating the neighborhood diameter. (DOCX 58 kb)
Genetics of response to cognitive behavior therapy in adults with major depression: a preliminary report
Creators: name: Andersson E
name: Schalling M
name: Lu Y
name: Mataix-Cols D
name: Sullivan P.F
name: Rück C
name: Svanborg C
name: Boberg J
name: Mattheisen M
name: Ljótsson B
name: Kaldo V
name: Kähler A.K
name: Crowley J.J
name: Mattsson S
name: Karlsson R
name: Hedman-Lagerlöf E
name: Lindefors N
name: Lavebratt C
name: Forsell E
name: El Alaoui S
Publisher: name: Nature Publishing Group
Year: 2019

description: Major depressive disorder is heritable and a leading cause of disability. Cognitive behavior therapy is an effective treatment for major depression. By quantifying genetic risk scores based on common genetic variants, the aim of this report was to explore the utility of psychiatric and cognitive trait genetic risk scores, for predicting the response of 894 adults with major depressive disorder to cognitive behavior therapy. The participants were recruited in a psychiatric setting, and the primary outcome score was measured using the Montgomery Åsberg Depression Rating Scale-Self Rated. Single-nucleotide polymorphism genotyping arrays were used to calculate the genomic risk scores based on large genetic studies of six phenotypes: major depressive disorder, bipolar disorder, attention-deficit/hyperactivity disorder, autism spectrum disorder, intelligence, and educational attainment. Linear mixed-effect models were used to test the relationships between the six genetic risk scores and cognitive behavior therapy outcome. Our analyses yielded one significant interaction effect (B = 0.09, p < 0.001): the autism spectrum disorder genetic risk score correlated with Montgomery Åsberg Depression Rating Scale-Self Rated changes during treatment, and the higher the autism spectrum disorder genetic load, the less the depressive symptoms decreased over time. The genetic risk scores for the other psychiatric and cognitive traits were not related to depressive symptom severity or change over time. Our preliminary results indicated, as expected, that the genomics of the response of patients with major depression to cognitive behavior therapy were complex and that future efforts should aim to maximize sample size and limit subject heterogeneity in order to gain a better understanding of the use of genetic risk factors to predict treatment outcome.
sakk1614_codes.zip
Creators: name: Schmid, Dominic
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 321104
subject: Cancer therapy (excl. chemotherapy and radiation therapy)

description: This file contains all code and raw data to reproduce the findings in the publication below: https://www.researchsquare.com/article/rs-4144547/v1
New bright soft X-ray selected ROSAT AGN II. Optical emission line properties
Creators: name: Grupe, D.
name: Beuermann, K.
name: Mannheim, K.
name: Thomas, H. -C.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the emission line properties of a sample of 76 bright soft X-ray selected ROSAT Active Galactic Nuclei. All optical counterparts are Seyfert 1 galaxies with rather narrow permitted lines, strong optical FeII line blends, and weak forbidden lines. By selection, they also have steep soft X-ray spectra when compared with typical Seyfert 1 galaxies. We discuss possible origins of these peculiar trends employing detailed correlation analyses, including a Principal Component Analysis. The optical spectra are presented in the Appendix.
description: 13 pages, 5 figures, the paper included all spectra is available at http://www.xray.mpe.mpg.de/~dgrupe/research/refereed.html
New Horizon and Vision of Teacher Education
Creators: name: Dhal, Pravat
Publisher: name: figshare
Year: 2020
Subjects: Education

description: AbstractIt is obvious that in the world scenario the teacher education had varied beginnings as to their thinking and imagination. Its development has been promoted according to their sociocultural and political set ups. Teacher education in every country is neglected due to ignorance. There are several pitfalls in this field. In spite of all these, it is true that teacher education in India is progressing as compare to other countries in the world. But it is said that “If we educate a boy, we educate one individual, if we educate one girl, we educate the whole family and if we educate one teacher, we educate the whole community.’’ It is said that, teacher is a ‘friend, philosopher and guide’ or ‘facilitator and manager’. If we introspect ourselves some questions raise: Does the teacher education institution provide this opportunity? Do we want really some changes in teacher education? Are we happy with present conditions of teacher education? Do we think about it? If yes, then how much time we think! Do we take accountability in our work? Do we have sincerity? Is there any synchronization of our words and deeds? Is there any hidden agenda? Do we look transparency in work? Do we love our profession? Are we open to every situation? Do we have excellence in our life? Do we have a good work culture? Do we have a positive attitude? Do we enjoy our profession? Certainly, the answer is No. Then, how do we want Excellency in teacher education! Opening more teacher education institutions for the sake of accessibility only will not sufficient. Along with this development of quality administration, quality management, quality curriculum, quality faculty, quality environment etc. are needed. What education should try to provide is
On Measuring $CP$ Violation in Neutral $B$-meson Decays at the $Υ(4S)$ Resonance
Creators: name: Fritzsch, H.
name: Wu, D.
name: Xing, Z.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Within the standard model we carry out an analysis of $CP$-violating observables in neutral $B$-meson decays at the $Υ(4S)$ resonance. Both time-dependent and time-integrated $CP$ asymmetries are calculated, without special approximations, to meet various possible measurements at symmetric and asymmetric $e^{+}e^{-}$ $B$ factories. We show two ways to distinguish between direct and indirect $CP$-violating effects in the $CP$-eigenstate channels such as $B^{0}_{d}/\bar{B}^{0}_{d}\rightarrow π^{+}π^{-}$ and $π^{0} K_{S}$. Reliable knowledge of the Cabibbo-Kobayashi-Maskawa phase and angles can in principle be extracted from measurements of some non-$CP$-eigenstate channels, e.g. $B^{0}_{d}/\bar{B}^{0}_{d}\rightarrow D^{\pm}π^{\mp}$ and $\stackrel{(-)}{D}$$^{(*)0}K_{S}$, even in the presence of significant final-state interactions.
description: Latex file 13 pages, CERN-TH.7194/94 and PVAMU-HEP-94-2 (Phys. Lett. B328 (1994) 477). (A few minor typing errors have been corrected.)
MOESM4 of Understanding the potential bias of variance components estimators when using genomic models
Creators: name: Cuyabano, Beatriz
name: A. Sørensen
name: Sørensen, Peter
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 4. Scatterplot of $$\lambda_{{\rm i}}$$ λ i versus $$(\mathbf{y}\prime \mathbf{U}_{{\rm i}})^{2}$$ ( y ′ U i ) 2 for one replicate on all the eight scenarios, when considering 3000 QTL and 2000 individuals. Distributions are presented for $${\mathbf{G}}$$ G assuming the genomic model with QTL plus markers.
Additional file 9 of Prognostic perspectives of PD-L1 combined with tumor-infiltrating lymphocytes, Epstein-Barr virus, and microsatellite instability in gastric carcinomas
Creators: name: Choi, Euno
name: Chang, Mee Soo
name: Byeon, Sun-ju
name: Jin, Heejin
name: Jung, Kyeong Cheon
name: Kim, Haeryoung
name: Lee, Kook Lae
name: Kim, Won
name: Park, Jin Hyun
name: Kim, Ki Hwan
name: Kim, Jin-Soo
name: Choi, In Sil
name: Han, Dong-Seok
name: Ahn, Hye Seong
name: Heo, Seung Chul
Publisher: name: figshare
Year: 2020
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 9: Supplemental Table 4. Univariate Analysis in MSI-high Gastric Carcinomas (n = 53) (corresponding to Fig. 4d & e)
Millepora compressa Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Cnidaria
Hydrozoa
Anthoathecata
Milleporidae
Millepora
Millepora compressa

description: Millepora compressa [spec. nov.]
M. ramis compressiusculis subdichotomis distantibus, poris undique prominulis scabris.
Habitat in M. Mediterraneo. D. D. Kaehler.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 792, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
On the Unitarity Triangles of the CKM Matrix
Creators: name: WU, Dan-di
name: XING, Zhi-zhong
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The unitarity triangles of the $3\times 3$ Cabibbo-Kobayashi-Maskawa (CKM) matrix are studied in a systematic way. We show that the phases of the nine CKM rephasing invariants are indeed the outer angles of the six unitarity triangles and measurable in the $CP$-violating decay modes of $B_{d}$ and $B_{s}$ mesons. An economical notation system is introduced for describing properties of the unitarity triangles. To test unitarity of the CKM matrix we present some approximate but useful relations among the sides and angles of the unitarity triangles, which can be confronted with the accessible experiments of quark mixing and $CP$ violation.
description: 9 Latex pages; LMU-07/94 and PVAMU-HEP-94-5 (A few minor changes are made, accepted for publication in Phys. Lett. B)
Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways
Creators: name: Noblin E.S
name: Kleinman A
name: Sazonova O.V
name: McCreight J.C
name: Furlotte N.A
name: Fontanillas P
name: Wang X
name: Shringarpure S
name: Pitts S.J
name: Hjerling-Leffler J
name: Bell R.K
name: Tiemeier H
name: Wilson C.H
name: Elson S.L
name: Stringer S
name: Sullivan P.F
name: Mountain J.L
name: Hammerschlag A.R
name: Huber K.E
name: Alipanahi B
name: Shelton J.F
name: Nagel M
name: Auton A
name: Savage J.E
name: Bryc K
name: Skene N
name: Bryois J
name: Agee M
name: Muñoz-Manchado A.B
name: Northover C.A.M
name: Litterman N.K
name: Jansen P.R
name: McIntyre M.H
name: Hinds D.A
name: Vacic V
name: Benjamins J.S
name: Sathirapongsasuti J.F
name: Posthuma D
name: Smit A.B
name: White T
name: Tian C
name: Watanabe K
name: Tung J.Y
name: van der Sluis S
name: Van Someren E.J.W
name: de Leeuw C.A
name: Polderman T.J.C
Publisher: name: Nature Publishing Group
Year: 2019

description: Insomnia is the second most prevalent mental disorder, with no sufficient treatment available. Despite substantial heritability, insight into the associated genes and neurobiological pathways remains limited. Here, we use a large genetic association sample (n = 1,331,010) to detect novel loci and gain insight into the pathways, tissue and cell types involved in insomnia complaints. We identify 202 loci implicating 956 genes through positional, expression quantitative trait loci, and chromatin mapping. The meta-analysis explained 2.6% of the variance. We show gene set enrichments for the axonal part of neurons, cortical and subcortical tissues, and specific cell types, including striatal, hypothalamic, and claustrum neurons. We found considerable genetic correlations with psychiatric traits and sleep duration, and modest correlations with other sleep-related traits. Mendelian randomization identified the causal effects of insomnia on depression, diabetes, and cardiovascular disease, and the protective effects of educational attainment and intracranial volume. Our findings highlight key brain areas and cell types implicated in insomnia, and provide new treatment targets.
Additional file 1 of Diabetes risk loci-associated pathways are shared across metabolic tissues
Creators: name: Bouland, Gerard A.
name: Beulens, Joline W. J.
name: Nap, Joey
name: van der Slik, Arno R.
name: Zaldumbide, Arnaud
name: ’t Hart, Leen M.
name: Slieker, Roderick C.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. a Frequency of tissues in which a certain eGene was identified. X-axis, genes under influence of a diabetes SNP, y-axis, frequency of tissues in which the QTL was identified. Figure S2. Scatterplot of expression of RP11-613D13.10 versus the expression of HSD17B12. X-axis, expression of RP11-613D13.10; y-axis expression of HSD17B12. Figure S3. a Frequency of the number of times an enriched pathway was found across the twelve tested tissues. X-axis, pathway investigated; y-axis, frequency of tissues. Blue bars indicate pathways associated with HLA-genes. Figure S4. Relation between KEGG pathways identified in each of the tissues. Tissues include subcutaneous fat (a), visceral fat (b), sigmoid colon (c), transverse colon (d), pituitary (e), small intestine (f), stomach (g), thyroid (h), whole blood (i). Figure S5. Chromatin state segmentations for rs601945 in various tissues and cell lines (data from Epigenomics Roadmap). Plus-symbol indicates a SNP in LD and blood cell types are colored in blue. X-axis, location on the genome; y-axis cell type.
Genome-Wide Association Analysis of Neonatal White Matter Microstructure
Creators: name: Ahn, M
name: Zou, F
name: Szatkiewicz, J.P
name: Jha, S.C
name: Knickmeyer, R.C
name: Blanchett, R
name: Styner, M
name: Zhang, J
name: Crowley, J.J
name: Zhu, H
name: Gilmore, J.H
name: Xia, K
Publisher: name: Oxford University Press
Year: 2021

description: A better understanding of genetic influences on early white matter development could significantly advance our understanding of neurological and psychiatric conditions characterized by altered integrity of axonal pathways. We conducted a genome-wide association study (GWAS) of diffusion tensor imaging (DTI) phenotypes in 471 neonates. We used a hierarchical functional principal regression model (HFPRM) to perform joint analysis of 44 fiber bundles. HFPRM revealed a latent measure of white matter microstructure that explained approximately 50% of variation in our tractography-based measures and accounted for a large proportion of heritable variation in each individual bundle. An intronic SNP in PSMF1 on chromosome 20 exceeded the conventional GWAS threshold of 5 × 10-8 (p = 4.61 × 10-8). Additional loci nearing genome-wide significance were located near genes with known roles in axon growth and guidance, fasciculation, and myelination.
Infrared spectra of C2H4 dimer and trimer
Creators: name: Barclay, A. J.
name: Esteki, K.
name: McKellar, A. R. W.
name: Moazzen-Ahmadi, N.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: FOS: Physical sciences

description: Spectra of ethylene dimers and trimers are studied in the nu11 and (for the dimer) nu9 fundamental band regions of C2H4 (~2990 and 3100 cm-1) using a tunable optical parametric oscillator source to probe a pulsed supersonic slit jet expansion. The deuterated trimer has been observed previously, but this represents the first rotationally resolved spectrum of (C2H4)3. The results support the previously determined cross-shaped (D2d) dimer and barrel-shaped (C3h or C3) trimer structures. However, the dimer spectrum in the nu9 fundamental region of C2H4 is apparently very perturbed and a previous rotational analysis is not well verified.
description: 21 pages, 4 figures
On Test of CPT Symmetry in CP Violating B Decays
Creators: name: Xing, Zhi-zhong
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Considering that the existing experimental limit for $CPT$ violation is still poor, we explore various possible ways to test $CPT$ symmetry in $CP$-violating $B$ decays at $e^{+}e^{-}$ $B$ factories and hadron machines. We find that it is difficult to distinguish between the effect of direct $CP$ violation and that of $CPT$ violation in the time-integrated measurements of neutral $B$ decays to $CP$ eigenstates such as $ψK_{S}$ and $π^{+}π^{-}$. Instead, a cleaner signal of small $CPT$ violation may appear in the time-integrated $CP$ asymmetries for a few non-$CP$-eigenstate channels, e.g., $B^{0}_{d}/\bar{B}^{0}_{d}\rightarrow D^{\pm}π^{\mp}$ and $\stackrel{(-)}{D}$$^{(*)0}K_{S}$. The time-dependent measurements of $CP$ asymmetries are available, in principle, to limit the size of $CPT$-violating effects in neutral $B$-meson decays.
description: 13 Latex pages; LMU-02/94 (Accepted for publication in Phys. Rev. D as a Rapid Communication)
Optical Observations of the Binary Pulsar System PSR B1718-19: Implications for Tidal Circularization
Creators: name: van Kerkwijk, M. H.
name: Kaspi, V. M.
name: Klemola, A. R.
name: Kulkarni, S. R.
name: Lyne, A. G.
name: Van Buren, D.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report on Keck and Hubble Space Telescope optical observations of the eclipsing binary pulsar system PSR B1718-19, in the direction of the globular cluster NGC 6342. These reveal a faint star ($m_{\rm F702W}=25.21\pm0.07$; Vega system) within the pulsar's 0\farcs5 radius positional error circle. This may be the companion. If it is a main-sequence star in the cluster, it has radius $\rcomp\simeq0.3 \rsun$, temperature $\teff\simeq3600 $K, and mass $\mcomp\simeq0.3 \msun$. In many formation models, however, the pulsar (spun up by accretion or newly formed) and its companion are initially in an eccentric orbit. If so, for tidal circularization to have produced the present-day highly circular orbit, a large stellar radius is required, i.e., the star must be bloated. Using constraints on the radius and temperature from the Roche and Hayashi limits, we infer from our observations that $\rcomp\simlt0.44 \rsun$ and $\teff\simgt3300 $K. Even for the largest radii, the required efficiency of tidal dissipation is larger than expected for some prescriptions.
description: 10 pages, 2 figures, aas4pp2.sty. Accepted for publication in ApJ
Minimal Supersymmetric Higgs Boson Decay Rate in O(α_s^2) Perturbative QCD
Creators: name: Surguladze, Levan R.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A short presentation of the results of the analytical evaluation of the O(α_s^2) QCD contributions in the fermionic decay rates of the neutral CP-odd minimal supersymmetric Higgs particle is made. The corrections due to the nonvanishing quark masses are included. The results are presented both in terms of running and pole quark masses.
description: 8 pages, LATeX, preprint OITS 544 (University of Oregon, USA, June 1994)
On the coupling of heavy mesons to pions in QCD
Creators: name: Colangelo, P.
name: Deandrea, A.
name: Di Bartolomeo, N.
name: Feruglio, F.
name: Gatto, R.
name: Nardulli, G.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We compute the strong coupling constant $g_{P^* P π}$, with $P$ and $P^*$ respectively pseudoscalar and vector heavy mesons by using the QCD sum rules approach. Our computation is based on the evaluation of the time ordered product of currents between the vacuum and the soft pion state. The so-called parasitic terms are taken into account and give a contribution to the sum rule of the same order of the lowest lying state, while higher dimension non perturbative terms have small numerical effects. The infinite heavy quark mass limit is also examined.
description: 11 pages, LaTeX, UGVA-DPT 1994/06-856 and BARI-TH/94-171
Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss
Creators: name: Gao Y
name: Li C.-M
name: Goedegebure A.
name: Mäkitie A
name: Sullivan P.F
name: Yao S
name: Freidin M.B
name: Magnusson P.K.E
name: Nalls M.A
name: Schweinfurth J.M
name: Saarentaus E
name: Krebs K
name: Bishop C
name: Kaprio J
name: Tropitzsch A
name: Shiroma E
name: Pratt S
name: Lee I.-M
name: Heard-Costa N.L
name: Hjelmborg J.V.B
name: Nagtegaal A.P.
name: Williams F.M.K.
name: Trpchevska N
name: Satizabal C.L
name: Bizaki-Vallaskangas A
name: Cherny S
name: Canlon B
name: Morton C.C
name: Lauschke V.M
name: Leonard H
name: Mengel-From J
name: Gudjonsson A
name: Nygaard M
name: Lallemend F
name: Castellana F
name: Zhou Y
name: Hjerling-Leffler J
name: Launer L.J
name: Spankovich C
name: Seshadri S
name: Palviainen T
name: Concas M.P
name: Estonian Biobank Research Team
name: Quaranta N
name: Christensen K
name: Cederroth C.R.
name: Lowenheim H
name: Giersch A.B.S
name: Vona B
name: Oosterloo B.C
name: Hoffman H.J
name: Nardone G.G
name: Milani L
name: Elkon R
name: Rämö J
name: Sardone R
name: Kettunen J
name: Gudnason V
name: Shulman E
name: Kähler A.K
name: Girotto G
name: Hertzano R
name: Correa A
name: Simonsick E
name: Broer L
name: van Meurs J
name: Chasman D.I
Publisher: name: Cell Press
Year: 2022

description: Hearing loss is one of the top contributors to years lived with disability and is a risk factor for dementia. Molecular evidence on the cellular origins of hearing loss in humans is growing. Here, we performed a genome-wide association meta-analysis of clinically diagnosed and self-reported hearing impairment on 723,266 individuals and identified 48 significant loci, 10 of which are novel. A large proportion of associations comprised missense variants, half of which lie within known familial hearing loss loci. We used single-cell RNA-sequencing data from mouse cochlea and brain and mapped common-variant genomic results to spindle, root, and basal cells from the stria vascularis, a structure in the cochlea necessary for normal hearing. Our findings indicate the importance of the stria vascularis in the mechanism of hearing impairment, providing future paths for developing targets for therapeutic intervention in hearing loss.
Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations
Creators: name: Kuchenbaecker K
name: Vassos E
name: Bigdeli T.B
name: Sullivan P.F
name: Mowry B
name: Majara L
name: Schwarz E
name: Chen C.-Y
name: Su J
name: Chen J
name: Koen N
name: Peterson R.E
name: Strawbridge R.J
name: Brick L
name: Lam M
name: Huang H
name: Cuellar-Barboza A
name: Popejoy A.B
name: Periyasamy S
name: Edenberg H.J
name: Edwards A.C
name: Meyers J.L
name: Kalungi A
name: Stahl E.A
name: Walters R.K
name: Prieto M.L
name: Iyegbe C
name: Carey C.E
name: Martin A.R
name: Smoller J.W
name: Duncan L.E
Publisher: name: Cell Press
Year: 2019

description: Genome-wide association studies (GWASs) have focused primarily on populations of European descent, but it is essential that diverse populations become better represented. Increasing diversity among study participants will advance our understanding of genetic architecture in all populations and ensure that genetic research is broadly applicable. To facilitate and promote research in multi-ancestry and admixed cohorts, we outline key methodological considerations and highlight opportunities, challenges, solutions, and areas in need of development. Despite the perception that analyzing genetic data from diverse populations is difficult, it is scientifically and ethically imperative, and there is an expanding analytical toolbox to do it well. © 2019 Elsevier Inc.; With increasing representation of global populations in genetic studies, there is an opportunity for advanced methods development and a need for consensus “best practices” for analyzing datasets. We provide background on the scientific and ethical importance of including underrepresented groups in genetics research and offer guidance for genome-wide analysis of ancestrally diverse study cohorts.
Symmetry Principles toward Solutions of $μ$ Problem
Creators: name: Kim, Jihn E.
name: Nilles, Hans Peter
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We stress that a natural solution of the $μ$ problem requires two ingredients: a symmetry that would enforce $μ= 0$ as well as the occurence of a small breaking parameter that generates a nonzero $μ$. It is suggested that both the Peccei-Quinn symmetry and the spontaneously broken $R$ symmetry may be the sources of the needed $μ$ term in the minimal supersymmetric standard model provided that they are spontaneously broken at a scale $10^{10}-10^{12}$ GeV. To solve the strong CP problem with a hidden sector confining group, both of these symmetries are needed in superstring models with an anomalous $U(1)_A$.
description: Latex file, 13 pages
Time-Varying Fine-Structure Constant Requires Cosmological Constant
Creators: name: Kuhne, R. W.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Webb et al. presented preliminary evidence for a time-varying fine-structure constant. We show Teller's formula for this variation to be ruled out within the Einstein-de Sitter universe, however, it is compatible with cosmologies which require a large cosmological constant.
description: 3 pages, no figures, revtex, to be published in Mod. Phys. Lett. A
MOESM3 of Understanding the potential bias of variance components estimators when using genomic models
Creators: name: Cuyabano, Beatriz
name: A. Sørensen
name: Sørensen, Peter
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Plant Biology

description: Additional file 3. Scatterplot of $$\lambda_{{\rm i}}$$ λ i versus $$(\mathbf{y}\prime \mathbf{U}_{{\rm i}})^{2}$$ ( y ′ U i ) 2 for one replicate on all the eight scenarios, when considering 3000 QTL and 2000 individuals. Distributions are presented for $${\mathbf{G}}$$ G assuming the genomic model with markers only.
Multisolitons in a Two-dimensional Skyrme Model
Creators: name: Piette, B. M. A. G.
name: Schroers, B. J.
name: Zakrzewski, W. J.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Skyrme model can be generalised to a situation where static fields are maps from one Riemannian manifold to another. Here we study a Skyrme model where physical space is two-dimensional euclidean space and the target space is the two-sphere with its standard metric. The model has topological soliton solutions which are exponentially localised. We describe a superposition procedure for solitons in our model and derive an expression for the interaction potential of two solitons which only involves the solitons' asymptotic fields. If the solitons have topological degree 1 or 2 there are simple formulae for their interaction potentials which we use to prove the existence of solitons of higher degree. We explicitly compute the fields and energy distributions for solitons of degrees between one and six and discuss their geometrical shapes and binding energies.
description: 20 pages, Latex, 6 figures available from BJS on request, DTP 94-23
Parameterization Invariance and the Resolution of the Unitary Gauge Puzzle
Creators: name: Kelly, P. F.
name: Kobes, R.
name: Kunstatter, G.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We examine the calculation of the critical temperature $T_c$ for the restoration of a spontaneously broken symmetry. Motivated by a set of recently developed gauge dependence identities, we give a gauge and parameterization independent definition of this temperature in terms of the physical mass of the scalar particle as determined by the propagator pole. As an explicit illustration, we consider the Abelian Higgs model in the unitary gauge, where the usual definition of the critical temperature based upon the effective potential leads to an erroneous result. We show how the gauge invariant definition reproduces the correct result as found in the ``renormalizable'' parameterizations.
description: MIT--CTP--2299, WIN--93--09, ENSLAPP--A--470/94, NSF--ITP--94--62, In plain TeX
Additional file 1 of SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism
Creators: name: Zhang, Yue
name: Li, Ting
name: Pan, Miaoxia
name: Wang, Wei
name: Huang, Wenhui
name: Yuan, Yafei
name: Xie, Zhanzhan
name: Chen, Yixin
name: Peng, Jun
name: Li, Xu
name: Meng, Ying
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 1 Original blots of Western Blot analysis. The figure legend of this file is the same as the legend of the corresponding figure in the main text.
Additional file 4: of A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle
Creators: name: Martin, Scott
name: Abhilash Chiramel
name: Schmidt, Marie
name: Chen, Yu-Chi
name: Whitt, Nadia
name: Watt, Ari
name: Dunham, Eric
name: Shifflett, Kyle
name: Traeger, Shelby
name: Leske, Anne
name: Buehler, Eugen
name: Martellaro, Cynthia
name: Brandt, Janine
name: Wendt, Lisa
name: MĂźller, Andreas
name: Peitsch, Stephanie
name: Best, Sonja
name: JĂźrgen Stech
name: Finke, Stefan
name: RĂśmer-OberdĂśrfer, Angela
name: Groseth, Allison
name: Feldmann, Heinz
name: Hoenen, Thomas
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 60506 Virology

description: Results of common seed analysis, pdf file format. (PDF 2900 kb)
Tipping the magnetic instability in paramagnetic Sr$_3$Ru$_2$O$_7$ by Fe impurities
Creators: name: Zhu, M.
name: Wang, Y.
name: Li, P. G.
name: Ge, J. J.
name: Tian, W.
name: Keavney, D.
name: Mao, Z. Q.
name: Ke, X.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report the magnetic and electronic properties of the bilayer ruthenate Sr$_3$Ru$_2$O$_7$ upon Fe substitution for Ru. We find that Sr$_3$(Ru$_{1-x}$Fe$_x$)$_2$O$_7$ shows a spin-glass-like phase below 4 K for $x$ = 0.01 and commensurate E-type antiferromagnetically ordered insulating ground state characterized by the propagation vector $q_c$ = (0.25 0.25 0) for $x$ $\geq$ 0.03, respectively, in contrast to the paramagnetic metallic state in the parent compound with strong spin fluctuations occurring at wave vectors $q$ = (0.09 0 0) and (0.25 0 0). The observed antiferromagnetic ordering is quasi-two-dimensional with very short correlation length along the $c$ axis, a feature similar to the Mn-doped Sr$_3$Ru$_2$O$_7$. Our results suggest that this ordered ground state is associated with the intrinsic magnetic instability in the pristine compound, which can be readily tipped by the local magnetic coupling between the 3$d$ orbitals of the magnetic dopants and Ru 4$d$ orbitals.
description: 19 pages, 4 figures
Broad band spectral properties of Seyfert 1 galaxies observed with BeppoSAX
Creators: name: Piro, L.
name: De Rosa, A.
name: Dadina, M.
name: Nicastro, F.
name: Matt, G.
name: Perola, G. C.
name: Grandi, P.
name: Fiore, F.
name: Mineo, T.
name: Maraschi, L.
name: Haardt, F.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We will present some results on the broad--band observations of BeppoSAX of the bright Seyfert galaxies NGC 4151 and NGC 5548.
description: 5 pages, 4 figures, Proc. of the 32 COSPAR Ass., Session E1.1 "Broad Band X-Ray Spectra of Cosmic Sources, ed.s K. Makishima, L. Piro, T. Takahashi, Advances in Space Research, in press
MOESM2 of Understanding the potential bias of variance components estimators when using genomic models
Creators: name: Cuyabano, Beatriz
name: A. Sørensen
name: Sørensen, Peter
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology

description: Additional file 2. Scatterplot of $$\lambda_{{\rm i}}$$ λ i versus $$({\mathbf{y}}\prime{\mathbf{U}}_{{\rm i}})^{2}$$ ( y ′ U i ) 2 for one replicate on all the eight scenarios, when considering 3000 QTL and 2000 individuals. Distributions are presented for $${\mathbf{G}}$$ G assuming the true model (QTL only).