cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
PJI-TNM als neues Klassifikationssystem für Endoprotheseninfektionen
Creators: name: Rupp, Markus
name: Kerschbaum, Maximilian
name: Freigang, Viola
name: Bärtl, Susanne
name: Baumann, Florian
name: Trampuz, Andrej
name: Alt, Volker
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: KNEE ARTHROPLASTY; HIP; Biofilms; Arthroplasty; Periprosthetic joint infections; Retrospective studies; TNM classification
subject: 610 Medizin

description: Background Current classifications for periprosthetic joint infections (PJIs) often lack a detailed description of the overall underlying situation of a patient. The PJI-TNM classification uses the principles of the TNM classification from oncology for the description of critical parameters in PJIs: affected joint, type of implant and implant stability, soft tissue conditions, maturity of biofilm formation, causative microorganism, comorbidities of the patient and recurrence of infection. The aim of the current work is to evaluate the feasibility of this new PJI-TNM classification in clinical practice. Methods The PJI-TNM classification was used in 20 patients with hip, knee and shoulder PJIs. Based on a retrospective chart review, the respective parameters T (tissue and implants), N (non-eukaryotic cells and fungi), M (morbidity) and r (reinfection) were classified for each case. Results All 20 cases (12 male, 8 female, average age 72.2 (40-88 years)) with 13 hip, 6 knee and 1 shoulder PJIs were to be classified with the new TNM-PJI classification system. There was a considerable heterogeneity among the cases: 12 protheses were fixed (T0), 6 were loosened (T1) and 2 were associated with a soft tissue defect (T2). Biofilm formation was considered immature in 7 cases (N0). Out of the PJIs, 13 were considered to be associated with mature biofilm formation. Out of the patients, 9 were systemically not or only mildly compromised (M0), 7 patients moderately (M1) and 3 patients (M2) severely compromised. One patient refused surgical treatment (M3a). Recurrent infections (r) were diagnosed in three cases. Conclusions The principles of the TNM classification from oncology can also be used for the classification of PJIs. Despite the limited number of cases in this study, a considerable heterogeneity of the evaluated PJIs is shown, which is a phenomenon that is also known from clinical practice. This heterogeneity can be adequately addressed by this new classification, which might be beneficial in decision-making in the future.
uPA‐PAI‐1 heteromerization promotes breast cancer progression by attracting tumorigenic neutrophils
Creators: name: Uhl, Bernd
name: A Mittmann, Laura
name: Dominik, Julian
name: Hennel, Roman
name: Smiljanov, Bojan
name: Haring, Florian
name: B Schaubächer, Johanna
name: Braun, Constanze
name: Padovan, Lena
name: Pick, Robert
name: Canis, Martin
name: Schulz, Christian
name: Mack, Matthias
name: Gutjahr, Ewgenija
name: Sinn, Peter
name: Heil, Jörg
name: Steiger, Katja
name: Kanse, Sandip M
name: Weichert, Wilko
name: Sperandio, Markus
name: Lauber, Kirsten
name: Krombach, Fritz
name: Reichel, Christoph A
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: PLASMINOGEN-ACTIVATOR INHIBITOR-1; ADJUVANT CHEMOTHERAPY; BLOOD-VESSELS; HIGH-RISK; UROKINASE; RECEPTOR; TYPE-1; COMPLEX; PAI-1; THERAPY; biomarker; breast cancer; fibrinolysis; innate immunity; neutrophils
subject: 610 Medizin

description: High intratumoral levels of urokinase-type plasminogen activator (uPA)-plasminogen activator inhibitor-1 (PAI-1) heteromers predict impaired survival and treatment response in early breast cancer. The pathogenetic role of this protein complex remains obscure. Here, we demonstrate that heteromerization of uPA and PAI-1 multiplies the potential of the single proteins to attract pro-tumorigenic neutrophils. To this end, tumor-released uPA-PAI-1 utilizes very low-density lipoprotein receptor and mitogen-activated protein kinases to initiate a pro-inflammatory program in perivascular macrophages. This enforces neutrophil trafficking to cancerous lesions and skews these immune cells toward a pro-tumorigenic phenotype, thus supporting tumor growth and metastasis. Blockade of uPA-PAI-1 heteromerization by a novel small-molecule inhibitor interfered with these events and effectively prevented tumor progression. Our findings identify a therapeutically targetable, hitherto unknown interplay between hemostasis and innate immunity that drives breast cancer progression. As a personalized immunotherapeutic strategy, blockade of uPA-PAI-1 heteromerization might be particularly beneficial for patients with highly aggressive uPA-PAI-1(high) tumors.
Exploring Viral Interference Using Peptides: Molecular Determinants of HIV‐1 Inhibition by a Peptide Derived from Human Pegivirus‐1 Envelope Protein E2
Creators: name: Hoffmann, Rebecca
name: Ruegamer, Tamara
name: Schaubächer, Johanna
name: Rohrhofer, Anette
name: Kirmeß, Peter
name: Fiebig, Karen M.
name: Schmidt, Barbara
name: Eichler, Jutta
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: ; gp120 V3 loop; HIV-1; human pegivirus; peptides; viral interference
subject: 610 Medizin

description: Co-infection with the human pegivirus 1 (HPgV-1) often has a beneficial effect on disease progression in HIV-1-infected individuals. Several HPgV-1 proteins and peptides, including a 20-mer peptide (P6-2) derived from the N-terminal region of the HPgV-1 surface protein E2, have been associated with this phenomenon, which is referred to as viral interference. We identified the cysteine residues, the hydrophobic core tetrapeptide, as well as the C-terminal negative charge as key factors for the HIV-1 inhibitory activity of P6-2. Analysis of mutations in P6-2-resistant HIV-1 indicated a binding site for the peptide in the HIV-1 envelope glycoprotein gp120. In fact, P6-2 was shown to bind to soluble gp120, as well as to a peptide presenting the gp120 V3 loop. Furthermore, the HIV-1 inhibitory activity of P6-2 could be revoked by the V3 loop peptide, thus indicating a molecular mechanism that involves interaction of P6-2 with the gp120 V3 loop.
Additional file 4: Figure S2. of Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells
Creators: name: Vad-Nielsen, Johan
name: Jakobsen, Kristine
name: Daugaard, Tina Fuglsang
name: Thomsen, Rune
name: Brügmann, Anja
name: Boe Sørensen
name: Nielsen, Anders
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: TSA effects on CBX1, CBX3 and CBX5 expression. A) mRNA expression analysis of the CBX1, CBX3 and CBX5 response towards TSA. Relative expression levels of CBX mRNA in MCF7 and MDA-MB-231 cells after 24 h treatment with TSA or control DMSO. Relative expression was calculated from RT-qPCR using GAPDH expression for normalization. For all panels, bars represent mean values with standard deviations. B) Immunofluorescence analysis of HP1α (upper panels) or DAPI staining in MDA-MB-231 cells either untreated or TSA treated for 24 h. C) Zooming in on a representative immunofluorescence analysis of HP1α in MDA-MB-231 cells with arrows pointing on heterochromatic spots. (PDF 914 kb)
Aglotingis DRAKE 1954
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Aglotingis

description: Gattung Aglotingis DRAKE, 1954
Aglotingis basilewskyi SCHOUTEDEN, 1955 *
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 130, DOI: 10.5281/zenodo.7507194
title: ÐÐµÑÐ¾Ð´Ñ Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ Ð¿ÑÐ¸Ð½ÑÑÐ¸Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½ÑÐµÑÐºÐ¸Ñ ÑÐµÑÐµÐ½Ð¸Ð¹ Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸ÑÑ , Ð¾Ð±ÐµÑÐ¿ÐµÑÐ¸Ð²Ð°ÑÑÐ¸Ñ Ð¸Ð½ÑÑÐ°ÑÑÑÑÐºÑÑÑÑ ÑÐµÐ»ÐµÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¹
title: ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÑ 5.2.6. ÐÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½Ñ
titleType: Subtitle
Creators: name: ÐÐ¾Ð³Ð¸Ð½Ð¾Ð², ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: Ð¢ÐµÐ»ÐµÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¸
ÐÑÐ¸Ð½ÑÑÐ¸Ðµ ÑÐµÑÐµÐ½Ð¸Ð¹
Ð¼ÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½Ñ
Ð¼ÐµÑÐ¾Ð´Ñ
Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ
Ð¾Ð¿ÑÐ¸Ð¼Ð¸Ð·Ð°ÑÐ¸Ñ

description: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð² Ð¿ÑÐ¸Ð½ÑÑÐ¸Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½ÑÐµÑÐºÐ¸Ñ ÑÐµÑÐµÐ½Ð¸Ð¹ Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸ÑÑ, Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÑÑÐ¸Ñ Ð¿Ð¾Ð´Ð´ÐµÑÐ¶ÐºÑ ÑÐµÐ»ÐµÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¹ Ð² Ð¿ÐµÑÐ¸Ð¾Ð´ Ð°ÐºÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¸ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÑ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¹ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð²Ð¾ÑÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð½ÑÐ¼ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÐµÐ¼ Ð½Ð°ÑÑÐ½ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹. Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ ÑÐµÐ¾ÑÐµÑÐ¸ÐºÐ¾-Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð¾Ð»Ð¾Ð¶ÐµÐ½Ð¸Ð¹ Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð², ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²ÑÑÑÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑ Ð¿ÑÐ¸Ð½ÑÑÐ¸Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½ÑÐµÑÐºÐ¸Ñ ÑÐµÑÐµÐ½Ð¸Ð¹ Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸ÑÑ, Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÑÑÐ¸Ñ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ðµ ÑÐµÐ»ÐµÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð¸Ð½ÑÑÐ°ÑÑÑÑÐºÑÑÑÑ. ÐÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ñ Ð¼Ð¾Ð´ÐµÐ»Ð¸ Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ, Ð°Ð´Ð°Ð¿ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐµ Ðº ÑÐ¿ÐµÑÐ¸ÑÐ¸ÐºÐµ ÑÐµÐ»ÐµÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð¸Ð½ÑÑÐ°ÑÑÑÑÐºÑÑÑÑ Ñ Ð¾ÑÐµÐ½ÐºÐ¾Ð¹ Ð¸Ñ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð° Ð´Ð»Ñ ÑÐ»ÑÑÑÐµÐ½Ð¸Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð¸ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÐºÐ¾Ð½ÐºÑÑÐµÐ½ÑÐ¾ÑÐ¿Ð¾ÑÐ¾Ð±Ð½Ð¾ÑÑÐ¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¹.
Additional file 1: Table S1. of Tissue expression and antibacterial activity of host defense peptides in chicken
Creators: name: Lee, Mi
name: Hyun-Jun Jang
name: Deivendran Rengaraj
name: Seo-Yeong Yang
name: Han, Jae
name: Lamont, Susan
name: Womack, James
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Primers used in this study. (DOCX 14 kb)
Additional file 4: Figure S4. of Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas
Creators: name: Shamblott, Michael
name: O’Driscoll, Marci
name: Gomez, Danielle
name: McGuire, Dustin
Publisher: name: Figshare
Year: 2016
Subjects: Cell Biology
Molecular Biology
Science Policy
Computational Biology

description: Expression of NGN3 and hairy and enhancer of split-1 (HES1) mRNA following treatment with TRKB antagonist ANA-12. Quantitative RTPCR results of four biological replicate samples (A–D) treated with ANA-12 for four days. RQ, relative quantification of NGN3 and HES1 normalized to the level of cyclophillin A. ΔCt, change in threshold cycle (Ct). Mean and standard error of the mean (SEM), results of Student’s t-test (TTEST) and percentage of control are shown. (DOCX 50 kb)
Additional file 2: of Effectiveness of enhanced cognitive behavioral therapy (CBT-E) for eating disorders: study protocol for a randomized controlled trial
Creators: name: Jong, Martie De
name: Korrelboom, Kees
name: Meer, Iris Van Der
name: Deen, Mathijs
name: Hoek, Hans
name: Spinhoven, Philip
Publisher: name: Figshare
Year: 2016
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: SPIRIT figure: schedule of enrollment, interventions, and assessments. (DOC 57 kb)
Additional file 1: of Alcohol consumption and binge drinking in early pregnancy. A cross-sectional study with data from the Copenhagen Pregnancy Cohort
Creators: name: Iversen, Mette
name: SĂ¸Rensen, Nina
name: Broberg, Lotte
name: Damm, Peter
name: Hedegaard, Morten
name: Tabor, Ann
name: Hegaard, Hanne
Publisher: name: Figshare
Year: 2015
Subjects: subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Questionnaire. (PDF 823 kb)
Additional file 1: of Postoperative pulmonary complications following major elective abdominal surgery: a cohort study
Creators: name: Patel, Kamlesh
name: Hadian, Fatemeh
name: Ali, Aysha
name: Broadley, Graham
name: Evans, Kate
name: Horder, Claire
name: Johnstone, Marianne
name: Langlands, Fiona
name: Matthews, Jake
name: Prithish Narayan
name: Rallon, Priya
name: Roberts, Charlotte
name: Shah, Sonali
name: Vohra, Ravinder
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Developmental Biology
subject: Marine Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Supplementary tables. (DOCX 23Â kb)
Agramma STEPHENS 1829
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Agramma

description: Gattung Agramma STEPHENS, 1829
Agramma atricapillum (SPINOLA, 1837) * Agramma blandulum (HORVÁTH, 1905) Agramma confusum (PUTON, 1879)
Agramma fallax (HORVÁTH, 1906)
Agramma femorale THOMSON, 1871 Agramma laetum (FALLÉN, 1807
Agramma minutum HORVÁTH, 1874 Agramma nigrum FIEBER, 1844
Agramma ruficorne (GERMAR, 1835) Agramma subnotatum PÉRICART, 1981 * Agramma tropidopterum FLOR, 1860
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 130, DOI: 10.5281/zenodo.7507194
Additional file 1: of Effectiveness of enhanced cognitive behavioral therapy (CBT-E) for eating disorders: study protocol for a randomized controlled trial
Creators: name: Jong, Martie De
name: Korrelboom, Kees
name: Meer, Iris Van Der
name: Deen, Mathijs
name: Hoek, Hans
name: Spinhoven, Philip
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 125 kb)
Neurological symptoms and complications in predominantly hospitalized COVID‐19 patients: Results of the European multinational Lean European Open Survey on SARS‐Infected Patients (LEOSS)
Creators: name: Kleineberg, Nina N.
name: Knauss, Samuel
name: Gülke, Eileen
name: Pinnschmidt, Hans O.
name: Jakob, Carolin E. M.
name: Lingor, Paul
name: Hellwig, Kerstin
name: Berthele, Achim
name: Höglinger, Günter
name: Fink, Gereon R.
name: Endres, Matthias
name: Gerloff, Christian
name: Klein, Christine
name: Stecher, Melanie
name: Classen, Annika Y.
name: Rieg, Siegbert
name: Borgmann, Stefan
name: Hanses, Frank
name: Rüthrich, Maria M.
name: Hower, Martin
name: Tometten, Lukas
name: Haselberger, Martina
name: Piepel, Christiane
name: Merle, Uta
name: Dolff, Sebastian
name: Degenhardt, Christian
name: Jensen, Björn‐Erik O.
name: Vehreschild, Maria J. G. T.
name: Erber, Johanna
name: Franke, Christiana
name: Warnke, Clemens
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: ; COVID-19; neurological manifestations; SARS-CoV-2
subject: 610 Medizin

description: Background and purpose During acute coronavirus disease 2019 (COVID-19) infection, neurological signs, symptoms and complications occur. We aimed to assess their clinical relevance by evaluating real-world data from a multinational registry. Methods We analyzed COVID-19 patients from 127 centers, diagnosed between January 2020 and February 2021, and registered in the European multinational LEOSS (Lean European Open Survey on SARS-Infected Patients) registry. The effects of prior neurological diseases and the effect of neurological symptoms on outcome were studied using multivariate logistic regression. Results A total of 6537 COVID-19 patients (97.7% PCR-confirmed) were analyzed, of whom 92.1% were hospitalized and 14.7% died. Commonly, excessive tiredness (28.0%), headache (18.5%), nausea/emesis (16.6%), muscular weakness (17.0%), impaired sense of smell (9.0%) and taste (12.8%), and delirium (6.7%) were reported. In patients with a complicated or critical disease course (53%) the most frequent neurological complications were ischemic stroke (1.0%) and intracerebral bleeding (ICB; 2.2%). ICB peaked in the critical disease phase (5%) and was associated with the administration of anticoagulation and extracorporeal membrane oxygenation (ECMO). Excessive tiredness (odds ratio [OR] 1.42, 95% confidence interval [CI] 1.20-1.68) and prior neurodegenerative diseases (OR 1.32, 95% CI 1.07-1.63) were associated with an increased risk of an unfavorable outcome. Prior cerebrovascular and neuroimmunological diseases were not associated with an unfavorable short-term outcome of COVID-19. Conclusion Our data on mostly hospitalized COVID-19 patients show that excessive tiredness or prior neurodegenerative disease at first presentation increase the risk of an unfavorable short-term outcome. ICB in critical COVID-19 was associated with therapeutic interventions, such as anticoagulation and ECMO, and thus may be an indirect complication of a life-threatening systemic viral infection.
MOESM2 of Allele-specific antibodies to Plasmodium vivax merozoite surface protein-1: prevalence and inverse relationship to haemoglobin levels during infection
Creators: name: Sepúlveda, Nuno
name: Cristiane Morais
name: Mourão, Luiza
name: Matheus Freire
name: Fontes, Cor
name: Lacerda, Marcus
name: Drakeley, Chris
name: Érika Braga
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2: Table S1. Haplotype frequencies among 41 P. vivax malaria patients and their associations with the block 10 polymorphic recombinant antigens used in the study.
Ammianus DISTANT 1903
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Ammianus

description: Gattung Ammianus DISTANT, 1903
Ammianus philippinensis (DISTANT, 1902) *
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 130, DOI: 10.5281/zenodo.7507194
Campylosteira FIEBER 1844
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Campylosteira

description: Gattung Campylosteira FIEBER, 1844
Campylosteira eximia HORVÁTH, 1892
Campylosteira heissi PÉRICART, 1981
Campylosteira orientalis HORVÁTH, 1881
Campylosteira verna (FALLÉN, 1826) *
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 130, DOI: 10.5281/zenodo.7507194
Catoplatus SPINOLA 1837
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Catoplatus

description: Gattung Catoplatus SPINOLA, 1837
Catoplatus anticus (REUTER, 1880) Catoplatus carthusianus (GOEZE, 1778) Catoplatus citrinus HORVÁTH, 1897 Catoplatus crassipes (FIEBER, 1861) * Catoplatus fabricii (STÅL, 1868)
Catoplatus fulvicornis (JAKOVLEV, 1889) Catoplatus hilaris HORVÁTH, 1906 * Catoplatus horvathi (PUTON, 1878) Catoplatus immarginatus GOLUB, 1974 Catoplatus longipes PÉRICART, 1984 Catoplatus mamorensis BERGEVIN, 1922 Catoplatus minor ŠTUSÁK, 1975
Catoplatus nigriceps HORVÁTH, 1905
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on pages 130-131, DOI: 10.5281/zenodo.7507194
Nowcasting the COVID‐19 pandemic in Bavaria
Creators: name: Günther, Felix
name: Bender, Andreas
name: Katz, Katharina
name: Küchenhoff, Helmut
name: Höhle, Michael
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: Bayesian hierarchical model; COVID‐ 19; epidemic surveillance; infectious disease epidemiology; nowcasting
subject: 610 Medizin

description: To assess the current dynamics of an epidemic, it is central to collect information on the daily number of newly diseased cases. This is especially important in real-time surveillance, where the aim is to gain situational awareness, for example, if cases are currently increasing or decreasing. Reporting delays between disease onset and case reporting hamper our ability to understand the dynamics of an epidemic close to now when looking at the number of daily reported cases only. Nowcasting can be used to adjust daily case counts for occurred-but-not-yet-reported events. Here, we present a novel application of nowcasting to data on the current COVID-19 pandemic in Bavaria. It is based on a hierarchical Bayesian model that considers changes in the reporting delay distribution over time and associated with the weekday of reporting. Furthermore, we present a way to estimate the effective time-varying case reproduction number Re(t) based on predictions of the nowcast. The approaches are based on previously published work, that we considerably extended and adapted to the current task of nowcasting COVID-19 cases. We provide methodological details of the developed approach, illustrate results based on data of the current pandemic, and evaluate the model based on synthetic and retrospective data on COVID-19 in Bavaria. Results of our nowcasting are reported to the Bavarian health authority and published on a webpage on a daily basis (). Code and synthetic data for the analysis are available from and can be used for adaption of our approach to different data.
Cochlochila STAL 1873
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Cochlochila

description: Gattung Cochlochila STÅL, 1873
Cochlochila bullita (STÅL, 1873) *
Cochlochila conchata (MATSUMURA, 1913)
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 131, DOI: 10.5281/zenodo.7507194
COVID‐19: Recovery from Chemosensory Dysfunction. A Multicentre study on Smell and Taste
Creators: name: Niklassen, Andreas Steenholt
name: Draf, Julia
name: Huart, Caroline
name: Hintschich, Constantin
name: Bocksberger, Simone
name: Trecca, Eleonora Maria Consiglia
name: Klimek, Ludger
name: Le Bon, Serge D.
name: Altundag, Aytug
name: Hummel, Thomas
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: ; COVID-19 smell taste recovery psychophysical
subject: 610 Medizin

description: Objective/Hypothesis With the COVID-19 pandemic, chemosensory dysfunction are among the most prevalent symptoms. Most reports are subjective evaluations, which have been suggested to be unreliable. The objective is to test chemosensory dysfunction and recovery based on extensive psychophysical tests in COVID-19 during the course of the disease. Study Design Prospective cohort study. Methods A total of 111 patients from four centers participated in the study. All tested positive for SARS-COV-2 with RT-PCR. They were tested within 3 days of diagnosis and 28 to 169 days after infection. Testing included extensive olfactory testing with the Sniffin' Sticks test for threshold, discrimination and identification abilities, and with the Taste Sprays and Taste Strips for gustatory function for quasi-threshold and taste identification abilities. Results There was a significant difference in olfactory function during and after infection. During infection 21% were anosmic, 49% hyposmic, and 30% normosmic. After infection only 1% were anosmic, 26% hyposmic, and 73% normosmic. For gustatory function, there was a difference for all taste qualities, but significantly in sour, bitter, and total score. Twenty-six percent had gustatory dysfunction during infection and 6.5% had gustatory dysfunction after infection. Combining all tests 22% had combined olfactory and gustatory dysfunction during infection. After infection no patients had combined dysfunction. Conclusions Chemosensory dysfunction is very common in COVID-19, either as isolated smell or taste dysfunction or a combined dysfunction. Most people regain their chemosensory function within the first 28 days, but a quarter of the patients show persisting dysfunction, which should be referred to specialist smell and taste clinics for rehabilitation of chemosensory function. Level of Evidence 3 Laryngoscope, 2021
Copium THUNBERG 1822
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Copium

description: Gattung Copium THUNBERG, 1822
Copium adumbratum (HORVÁTH, 1891) * Copium brevicorne (JAKOVLEV, 1879)
Copium clavicorne clavicorne (LINNAEUS 1758) Copium clavicorne reyi WAGNER, 1954
Copium clavicorne siculum TAMANINI, 1974 Copium teucrii intermedium (REY, 1888) Copium teucrii iranum WAGNER, 1969
Copium teucrii teucrii (HOST, 1788)
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 131, DOI: 10.5281/zenodo.7507194
Corythucha STAL 1873
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Corythucha

description: Gattung Corythucha STÅL, 1873
Corythucha arcuata (SAY, 1832) *
Corythucha ciliata (SAY, 1832)
Gattung Cysteochila STÅL, 1873
Cysteochila impressa HORVÁTH, 1910 * Cysteochila stricta stricta (BERGEVIN, 1929) Cysteochila suspecta (SCHOUTEDEN, 1953) Cysteochila zavattarii MANCINI, 1953
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 131, DOI: 10.5281/zenodo.7507194
Derephysia SPINOLA 1837
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Derephysia

description: Gattung Derephysia SPINOLA, 1837
Derephysia cristata (PANZER, 1806)
Derephysia foliacea foliacea (FALLÉN, 1807) Derephysia rectinervis rectinervis PUTON, 1887 Derephysia sinuatocollis PUTON, 1879 *
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 131, DOI: 10.5281/zenodo.7507194
Impact of the coronavirus disease 2019 pandemic on stroke teleconsultations in Germany in the first half of 2020
Creators: name: Vollmuth, Christoph
name: Miljukov, Olga
name: Abu‐Mugheisib, Mazen
name: Angermaier, Anselm
name: Barlinn, Jessica
name: Busetto, Loraine
name: Grau, Armin J.
name: Guenther, Albrecht
name: Gumbinger, Christoph
name: Hubert, Nikolai
name: Hüttemann, Katrin
name: Klingner, Carsten
name: Naumann, Markus
name: Palm, Frederick
name: Remi, Jan
name: Rücker, Viktoria
name: Schessl, Joachim
name: Schlachetzki, Felix
name: Schuppner, Ramona
name: Schwab, Stefan
name: Schwartz, Andreas
name: Trommer, Adrian
name: Urbanek, Christian
name: Volbers, Bastian
name: Weber, Joachim
name: Wojciechowski, Claudia
name: Worthmann, Hans
name: Zickler, Philipp
name: Heuschmann, Peter U.
name: Haeusler, Karl Georg
name: Hubert, Gordian Jan
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: COVID-19; COVID-19; SARS-CoV-2; stroke; survey; telemedicine
subject: 610 Medizin

description: Background and purpose The effects of the coronavirus disease 2019 (COVID-19) pandemic on telemedical care have not been described on a national level. Thus, we investigated the medical stroke treatment situation before, during, and after the first lockdown in Germany. Methods In this nationwide, multicenter study, data from 14 telemedical networks including 31 network centers and 155 spoke hospitals covering large parts of Germany were analyzed regarding patients' characteristics, stroke type/severity, and acute stroke treatment. A survey focusing on potential shortcomings of in-hospital and (telemedical) stroke care during the pandemic was conducted. Results Between January 2018 and June 2020, 67,033 telemedical consultations and 38,895 telemedical stroke consultations were conducted. A significant decline of telemedical (p < 0.001) and telemedical stroke consultations (p < 0.001) during the lockdown in March/April 2020 and a reciprocal increase after relaxation of COVID-19 measures in May/June 2020 were observed. Compared to 2018-2019, neither stroke patients' age (p = 0.38), gender (p = 0.44), nor severity of ischemic stroke (p = 0.32) differed in March/April 2020. Whereas the proportion of ischemic stroke patients for whom endovascular treatment (14.3% vs. 14.6%; p = 0.85) was recommended remained stable, there was a nonsignificant trend toward a lower proportion of recommendation of intravenous thrombolysis during the lockdown (19.0% vs. 22.1%; p = 0.052). Despite the majority of participating network centers treating patients with COVID-19, there were no relevant shortcomings reported regarding in-hospital stroke treatment or telemedical stroke care. Conclusions Telemedical stroke care in Germany was able to provide full service despite the COVID-19 pandemic, but telemedical consultations declined abruptly during the lockdown period and normalized after relaxation of COVID-19 measures in Germany.
Dictyla STAL 1874
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Dictyla

description: Gattung Dictyla STÅL, 1874
Dictyla convergens (HERRICH- SCHAEFFER, 1835)
Dictyla echii (SCHRANK, 1782)
Dictyla fulvescens (KIRITSHENKO, 1952)
Dictyla humuli (FABRICIUS, 1794)
Dictyla indigena (WOLLASTON, 1858) *
Dictyla lithospermi RIBES, 1967
Dictyla lupuli (HERRICH- SCHAEFFER, 1837) Dictyla montandoni (HORVÁTH, 1885)
Dictyla nassata (PUTON, 1874)
Dictyla nodipennis (HORVÁTH, 1910)
Dictyla platyoma (FIEBER, 1861)
Dictyla rotundata (HERRICH- SCHAEFFER, 1835)
Dictyla ruficeps (HORVÁTH, 1905)
Dictyla sima SEIDENSTÜCKER, 1975
Dictyla subdola (HORVÁTH, 1905)
Dictyla triconula (SEIDENSTÜCKER, 1954) *
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on pages 131-132, DOI: 10.5281/zenodo.7507194
A retrospective analysis of trends in primary knee arthroplasty in Germany from 2008 to 2018
Creators: name: Worlicek, Michael
name: Koch, Matthias
name: Popp, Daniel
name: Freigang, Viola
name: Angele, Peter
name: Alt, Volker
name: Kerschbaum, Maximilian
name: Rupp, Markus
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: ;
subject: 610 Medizin

description: Unicompartimental and total knee arthroplasty is one of the most successful and most performed operations worldwide. In the last years the number of primary knee arthroplasty increased constantly. The aim of this study is to analyze the rising numbers of primary knee arthroplasty and to see how it is used in Germany. In this retrospective study data, provided by the Federal Statistical Office of Germany from 2008 to 2018 was analyzed, using operation codes from the German procedure classification system and characteristics like age, sex and type of the prosthesis. We found a slight increase of unicompartimental and total knee arthroplasty over the investigated 10 years from 150.504 in 2008 up to 168.479 procedures in 2018, with a maximum of 169.334 in 2017. Most patients were female and over 65 years old. Interestingly, there was an obvious decrease of regular TKA in the year 2013, with a relevant impact on the total number of procedures. In the following years the number rised again reaching the former level in 2015 and is still increasing. The highest increase was found in partial knee arthroplasty, with a constant rise every year, starting with 7988 in 2008 up to 21.072 in 2018. In contrast, we found a relevant reduction of constrained prosthesis in primary TKA, whereas the number of semi-constrained prosthesis in primary TKA is again rising after a decrease in 2015. We found that the number of bicondylar TKA and especially UKA increased from 2008 to 2018. Regarding an aging population, we can expect a rising number for Primary knee arthroplasty and in consequence a rising number of revision arthroplasty in the future. This will be a challenging cost factor for the healthcare system in Germany.
Additional file 7: of DrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing
Creators: name: Naiem Issa
name: Kruger, Jordan
name: Wathieu, Henri
name: Rajarajan Raja
name: Byers, Stephen
name: Dakshanamurthy, Sivanesan
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Tutorial outlining the manual implementation of the DrugGenEx-NET methodology. (DOCX 14Â kb)
Thermal Performance of a Liquid-cooling Assisted Thin Wickless Vapor Chamber
Creators: name: Mukhopadhyay, Arani
name: Pal, Anish
name: Gukeh, Mohamad Jafari
name: Megaridis, Constantine M.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Applied Physics (physics.app-ph)
subject: Hardware Architecture (cs.AR)
subject: Systems and Control (eess.SY)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The ever-increasing need for power consumption in electronic devices, coupled with the requirement for thinner size, calls for the development of efficient heat spreading components. Vapor chambers (VCs), because of their ability to effectively spread heat over a large area by two-phase heat transfer, seem ideal for such applications. However, creating thin and efficient vapor chambers that work over a wide range of power inputs is a persisting challenge. VCs that use wicks for circulating the phase changing media, suffer from capillary restrictions, dry-out, clogging, increase in size and weight, and can often be costly. Recent developments in wick-free wettability patterned vapor chambers replace traditional wicks with laser-fabricated wickless components. An experimental setup allows for fast testing and experimental evaluation of water-charged VCs with liquid-assisted cooling. The sealed chamber can maintain vacuum for long durations, and can be used for testing of very thin wick-free VCs. This work extends our previous study by decreasing overall thickness of the wick-free VC down to 3 mm and evaluates its performance. Furthermore, the impact of wettability patterns on VC performance is investigated, by carrying out experiments both in non-patterned and patterned VCs. Experiments are first carried out on a wick-free VC with no wettability patterns and comprising of an entirely superhydrophilic evaporator coupled with a hydrophobic condenser. Thereafter, wettability patterns that aid the rapid return of water to the heated site on the evaporator and improve condensation on the condenser of the vapor chamber are implemented. The thermal characteristics show that the patterned VCs outperform the non-patterned VCs under all scenarios. The patterned VCs exhibit low thermal resistance independent of fluid charging ratio withstanding higher power inputs without thermal dry-outs.
description: Presented at IEEE ITherm (Intersociety Conference on Thermal and Thermomechanical Phenomena in Electronic Systems) 2023. Orlando, FL, US. Corresponding: cmm@uic.edu
Endodontic management of traumatized permanent teeth: a comprehensive review
Creators: name: Krastl, G.
name: Weiger, R.
name: Filippi, A.
name: Van Waes, H.
name: Ebeleseder, K.
name: Ree, M.
name: Connert, T.
name: Widbiller, M.
name: Tjäderhane, L.
name: Dummer, P. M. H.
name: Galler, K.
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: avulsion; dental trauma; diagnosis; endodontic management; tooth fracture; tooth injuries
subject: 610 Medizin

description: The pulp plays a key role in the treatment of traumatic dental injuries (TDIs) and is strongly associated with the outcome, particularly in severe cases. A correct pulp diagnosis is essential as it forms the basis for developing the appropriate management strategy. However, many TDIs are complex, and their treatment requires a profound knowledge of the physiological and pathological responses of the affected tissues. This comprehensive review will look at the dentine-pulp complex and its interaction with the surrounding tissues following TDIs. The literature up to 2020 was reviewed based on several searches on PubMed and the Cochrane Library using relevant terms. In addition to the recently revised guidelines of the International Association of Dental Traumatology, this article aims to provide background information with a focus on endodontic aspects and to gather evidence on which a clinician can make decisions on the choice of the appropriate endodontic approach for traumatized permanent teeth.
Additional file 2: of Multispectral imaging of formalin-fixed tissue predicts ability to generate tumor-infiltrating lymphocytes from melanoma
Creators: name: Zipei Feng
name: Puri, Sachin
name: Moudgil, Tarsem
name: Wood, William
name: Hoyt, Clifford
name: Chichung Wang
name: Urba, Walter
name: Curti, Brendan
name: Bifulco, Carlo
name: Fox, Bernard
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplemental methods. Detailed immunohistochemistry methods for multispectral analysis. (DOCX 20Â kb)
Dictyonota CURTIS 1827
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Dictyonota

description: Gattung Dictyonota CURTIS, 1827
Dictyonota albipennis BAERENSPRUNG, 1858
Dictyonota atlantica PÉRICART, 1981
Dictyonota fuliginosa A. COSTA, 1853*
Dictyonota horvathi (KIRITSHENKO, 1914)
Dictyonota lepida (HORVÁTH, 1905)
Dictyonota marmorea BAERENSPRUNG, 1858 *
Dictyonota opaca (LINNAVUORI R., 1965)
Dictyonota phoenicea SEIDENSTÜCKER, 1963
Dictyonota strichnocera FIEBER, 1844
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 132, DOI: 10.5281/zenodo.7507194
Additional file 1: of The acute effects of targeted abdominal muscle activation training on spine stability and neuromuscular control
Creators: name: Southwell, Daniel
name: Hills, Nicole
name: McLean, Linda
name: Graham, Ryan
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Document containing the full listing and positions of tracking and calibration markers used to determine 3D whole body kinematics. (PDF 4Â kb)
Additional file 4: of Quantitative estimates of dietary intake with special emphasis on snacking pattern and nutritional status of free living adults in urban slums of Delhi: impact of nutrition transition
Creators: name: Singh, Archna
name: Gupta, Vidhu
name: Ghosh, Arpita
name: Lock, Karen
name: Suparna Ghosh-Jerath
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Percentage Distribution (PDF, .pdf); Percentage of households for different Nutrient Adequacy Ratio categories in study HHs. (PDF 137Â kb)
Elasmotropis STAL 1874
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Elasmotropis

description: Gattung Elasmotropis STÅL, 1874
Elasmotropis testacea selecta (HORVÁTH, 1891)
Elasmotropis testacea testacea (HERRICH- SCHAEFFER, 1830)*
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 132, DOI: 10.5281/zenodo.7507194
Offloading Revenue Maximization in Multi-UAV-Assisted Mobile Edge Computing for Video Stream
Creators: name: Li, Bin
name: Shan, Huimin
Publisher: name: arXiv
Year: 2024
Subjects: subject: Emerging Technologies (cs.ET)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Traditional video transmission systems assisted by multiple Unmanned Aerial Vehicles (UAVs) are often limited by computing resources, making it challenging to meet the demands for efficient video processing. To solve this challenge, this paper presents a multi-UAV-assisted Device-to-Device (D2D) mobile edge computing system for the maximization of task offloading profits in video stream transmission. In particular, the system enables UAVs to collaborate with idle user devices to process video computing tasks by introducing D2D communications. To maximize the system efficiency, the paper jointly optimizes power allocation, video transcoding strategies, computing resource allocation, and UAV trajectory. The resulting non-convex optimization problem is formulated as a Markov decision process and solved relying on the Twin Delayed Deep Deterministic policy gradient (TD3) algorithm. Numerical results indicate that the proposed TD3 algorithm performs a significant advantage over other traditional algorithms in enhancing the overall system efficiency.
description: 10 pages, 8 figures
Systematic Evaluation of Fluorination as Modification for Peptide‐Based Fusion Inhibitors against HIV‐1 Infection
Creators: name: Huhmann, Susanne
name: Nyakatura, Elisabeth K.
name: Rohrhofer, Anette
name: Moschner, Johann
name: Schmidt, Barbara
name: Eichler, Jutta
name: Roth, Christian
name: Koksch, Beate
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: GP41 CORE STRUCTURE; AMINO-ACIDS; PROTEOLYTIC STABILITY; MEMBRANE-FUSION; COILED-COIL; TYPE-1 GP41; SALT BRIDGE; PROTEIN; ENTRY; ENFUVIRTIDE; fluorinated amino acids; gp41; medicinal chemistry; protein engineering; protein-protein interactions
subject: 610 Medizin

description: With the emergence of novel viruses, the development of new antivirals is more urgent than ever. A key step in human immunodeficiency virus type 1 (HIV-1) infection is six-helix bundle formation within the envelope protein subunit gp41. Selective disruption of bundle formation by peptides has been shown to be effective; however, these drugs, exemplified by T20, are prone to rapid clearance from the patient. The incorporation of non-natural amino acids is known to improve these pharmacokinetic properties. Here, we evaluate a peptide inhibitor in which a critical Ile residue is replaced by fluorinated analogues. We characterized the influence of the fluorinated analogues on the biophysical properties of the peptide. Furthermore, we show that the fluorinated peptides can block HIV-1 infection of target cells at nanomolar levels. These findings demonstrate that fluorinated amino acids are appropriate tools for the development of novel peptide therapeutics.