cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Structural diversity of supramolecular networks formed between polycyanometalates and sulfur-based chalcogen bond donors
Creators: name: Streit, Tim-Niclas
name: Langwald, Jan
name: Gomila, Rosa M.
name: Frontera, Antonio
name: Malischewski, Moritz
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: supramolecular networks
subject: polycyanometalates
subject: chalcogen bond donors
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: The co-crystallization of S-(CF3)-dibenzothiophenium (“Umemoto” – abbreviated Ume) cations and polycyanometalates with different coordination geometries yields a large structural variety of supramolecular assemblies. In the case of [Ume+]2[Ni(CN)4]2−·CH2Cl2 all four cyanide groups of the square-planar dianion act as chalcogen bond acceptors whereas the sulfur atoms of the Umemoto cations act as biaxial chalcogen bond donors. For tetrahedral [Zn(CN)4]2− a more complex assembly of four Umemoto cations and two dianions is observed. In the case of [Ume+]3[Fe(CN)6]3−·CH2Cl2 one Umemoto cation even acts as a triaxial chalcogen bond donor whereas only 4 out of the 6 cyanide groups act as chalcogen bond acceptors. For [Ume+]3[W(CN)8]3− a polymeric chain structure is observed in which all Umemoto cations act as biaxial chalcogen bond donors. DFT investigations focus on the physical nature of the chalcogen bonds, encompassing energetic assessments, MEP surface plots, QTAIM, and NBO analysis, shedding light on the nature of chalcogen donor–acceptor interactions. The energetic results evidence that total contributions of chalcogen bonds in different synthons range from −7.6 to −16.3 kcal mol−1, surpassing that of hydrogen bonds that range from −4.9 to −11.8 kcal mol−1.
Power-Law Random Banded Matrix Ensemble as the Effective Model for Many-Body Localization Transition
Creators: name: Rao, Wen-Jia
Publisher: name: arXiv
Year: 2021
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We employ the power-law random band matrix (PRBM) ensemble with single tuning parameter $μ$ as the effective model for many-body localization (MBL) transition in random spin systems. We show the PRBM accurately reproduce the eigenvalue statistics on the entire phase diagram through the fittings of high-order spacing ratio distributions $P(r^{(n)})$ as well as number variance $Σ^{2}(l)$, in systems both with and without time-reversal symmetry. For the properties of eigenvectors, it's shown the entanglement entropy of PRBM displays an evolution from volume-law to area-law behavior which signatures an ergodic-MBL transition, and the critical exponent is found to be $ν=0.83\pm 0.15$, close to the value obtained in 1D physical model by exact diagonalization while the computational cost here is much less.
description: 8 pages, 6 figures
title: Treatment of dorsal defect finger with modified fibular free flap of great toe
Creators: name: Zhao, Linglong
name: Yu, Xuejun
name: Xiang, Shengtao
name: Zheng, Wen
name: Shi, Xiaoqiang
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: fibular side pulp flap of great toe
subject: finger
subject: transplantation
subject: microsurgery
subject: 610 Medical sciences; Medicine

description: Objectives/Interrogation: To evaluate the outcome of the procedure of using the free flap vascularized by the fibular side of the great toe to treat finger dorsal skin defect Methods: From June 2013 to August 2016, 18 patients with finger skin defects were repaired by modified fibular side[for full text, please go to the a.m. URL]
description: 14th Triennial Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT), 11th Triennial Congress of the International Federation of Societies for Hand Therapy (IFSHT)
Unidirectional quantum walk of two correlated particles: Separating bound-pair and unbound wavepacket components
Creators: name: Buarque, A. R. C.
name: Dias, W. S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 81V99, 81P40, 81Q93

description: We study the unidirectional transport of two-particle quantum wavepackets in a regular one-dimensional lattice. We show that the bound-pair state component behaves differently from unbound states when subjected to an external pulsed electric field. Thus, strongly entangled particles exhibit a quite distinct dynamics when compared to a single particle system. With respect to centroid motion, our numerical results are corroborated with an analytical expression obtained using a semi-classical approach. The wavefunction profile reveals that the particle-particle interaction induces the splitting of the initial wavepacket into two branches that propagate with specific directions and drift velocities. With a proper external field tunning, the wavepacket components can perform an unidirectional transport on the same or opposite directions. The amplitude of each mode is related to the degree of entanglement betweem particles, which presents a non-monotonic dependence on the interaction strength.
description: 6 pages, 4 figures
The dark side of the torsion: Dark Energy from propagating torsion
Creators: name: Benisty, David
name: Guendelman, Eduardo I.
name: van de Venn, Armin
name: Vasak, David
name: Struckmeier, Jürgen
name: Stoecker, Horst
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: An extension to the Einstein-Cartan (EC) action is discussed in terms of cosmological solutions. The torsion incorporated in the EC Lagrangian is assumed to be totally anti-symmetric, represented by a time-like axial vector $S^μ$. The dynamics of torsion is invoked by a novel kinetic term. Here we show that this kinetic term gives rise to dark energy, while the quadratic torsion term, emanating from the EC part, represents a stiff fluid that leads to a bouncing cosmology solution. A constraint on the bouncing solution is calculated using cosmological data from different epochs.
description: 6 pages, 2 figures; accepted in EPJC
Encoding of continuous perceptual choices in human early visual cortex
Creators: name: Barbieri, Riccardo
name: Töpfer, Felix M.
name: Soch, Joram
name: Bogler, Carsten
name: Sprekeler, Henning
name: Haynes, John-Dylan
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: continuous decision making
subject: functional magnetic resonance imaging
subject: encoding model
subject: Gaussian process regression
subject: early visual cortex
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: Research on the neural mechanisms of perceptual decision-making has typically focused on simple categorical choices, say between two alternative motion directions. Studies on such discrete alternatives have often suggested that choices are encoded either in a motor-based or in an abstract, categorical format in regions beyond sensory cortex. Methods: In this study, we used motion stimuli that could vary anywhere between 0 degrees and 360 degrees to assess how the brain encodes choices for features that span the full sensory continuum. We employed a combination of neuroimaging and encoding models based on Gaussian process regression to assess how either stimuli or choices were encoded in brain responses. Results: We found that single-voxel tuning patterns could be used to reconstruct the trial-by-trial physical direction of motion as well as the participants' continuous choices. Importantly, these continuous choice signals were primarily observed in early visual areas. The tuning properties in this region generalized between choice encoding and stimulus encoding, even for reports that reflected pure guessing. Discussion: We found only little information related to the decision outcome in regions beyond visual cortex, such as parietal cortex, possibly because our task did not involve differential motor preparation. This could suggest that decisions for continuous stimuli take can place already in sensory brain regions, potentially using similar mechanisms to the sensory recruitment in visual working memory.
Euler Obstructed Cooper Pairing: Nodal Superconductivity and Hinge Majorana Zero Modes
Creators: name: Yu, Jiabin
name: Chen, Yu-An
name: Sarma, Sankar Das
Publisher: name: arXiv
Year: 2021
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Since the proposal of monopole Cooper pairing in [Phys. Rev. Lett. 120, 067003 (2018)], considerable research efforts have been dedicated to the study of Cooper pairing order parameters constrained (or obstructed) by the nontrivial normal-state band topology at Fermi surfaces in 3D systems. In the current work, we generalize the topologically obstructed pairings between Chern states (like the monopole Cooper pairing) by proposing Euler obstructed Cooper pairing in 3D systems. The Euler obstructed Cooper pairing widely exists between two Fermi surfaces with nontrivial band topology characterized by nonzero Euler numbers; such Fermi surfaces can exist in 3D PT-protected spinless-Dirac/nodal-line semimetals with negligible spin-orbit coupling, where PT is the space-time inversion symmetry. An Euler obstructed pairing channel must have pairing nodes on the pairing-relevant Fermi surfaces, and the total winding number of the pairing nodes is determined by the sum or difference of the Euler numbers on the Fermi surfaces. In particular, we find that when the normal state is time-reversal invariant and the pairing is weak, a sufficiently-dominant Euler obstructed pairing channel with zero total momentum leads to nodal superconductivity. If the Fermi surface splitting is small, the resultant nodal superconductor hosts hinge Majorana zero modes. The possible dominance of the Euler obstructed pairing channel near the superconducting transition and the robustness of the hinge Majorana zero modes against disorder are explicitly demonstrated using effective or tight-binding models. Our work presents the first class of higher-order nodal superconductivity originating from the topologically obstructed Cooper pairing.
description: Close to the published version
Similarities between GSH, Hypoplasticity and KCR
Creators: name: Jiang, Yimin
name: Liu, Mario
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Accounting for elasto-plastic motion in granular media, hypoplasticity is a state-of-the-art constitutive model derived from data accumulated over many decades. In contrast, GSH, a hydrodynamic theory, is derived from general principles of physics, with comparatively few inputs from experiments, yet sporting an applicability ranging from static stress distribution via elasto-plastic motion to fast dense flow, including non-uniform ones such as a shear band. Comparing both theories, we find great similarities for uniform, slow, elasto-plastic motion. We also find that proportional paths and the Goldscheider rule used to construct barodesy, another, more recent constitutive model, are natural results of GSH's equations. This is useful as it gives these constitutive relations a solid foundation in physics, and in reverse, GSH a robust connection to reality. The same symbiotic relation exists between GSH and KCR, or Kamrin's non-local constitutive relation, a model that was successfully employed to account for a wide shear band in split bottom cells.
description: 5 fig
Quantum verification and estimation with few copies
Creators: name: Morris, Joshua
name: Saggio, Valeria
name: Gočanin, Aleksandra
name: Dakić, Borivoje
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: As quantum technologies advance, the ability to generate increasingly large quantum states has experienced rapid development. In this context, the verification and estimation of large entangled systems represents one of the main challenges in the employment of such systems for reliable quantum information processing. Though the most complete technique is undoubtedly full tomography, the inherent exponential increase of experimental and post-processing resources with system size makes this approach infeasible even at moderate scales. For this reason, there is currently an urgent need to develop novel methods that surpass these limitations. This review article presents novel techniques focusing on a fixed number of resources (sampling complexity), and thus prove suitable for systems of arbitrary dimension. Specifically, a probabilistic framework requiring at best only a single copy for entanglement detection is reviewed, together with the concept of selective quantum state tomography, which enables the estimation of arbitrary elements of an unknown state with a number of copies that is low and independent of the system's size. These hyper-efficient techniques define a dimensional demarcation for partial tomography and open a path for novel applications.
description: 20 pages, 4 figures, review article, very close to the published version
GIPC1 regulates MACC1-driven metastasis
Creators: name: Siegel, Franziska
name: Schmidt, Hannes
name: Juneja, Manisha
name: Smith, Janice
name: Herrmann, Pia
name: Kobelt, Dennis
name: Sharma, Kamal
name: Fichtner, Iduna
name: Walther, Wolfgang
name: Dittmar, Gunnar
name: Volkmer, Rudolf
name: Rathjen, Fritz G.
name: Schlag, Peter M.
name: Stein, Ulrike
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: MACC1
subject: GIPC1
subject: protein-protein interaction
subject: transcription factor
subject: patient survival prognosis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Identification of cancer metastasis-relevant molecular networks is desired to provide the basis for understanding and developing intervention strategies. Here we address the role of GIPC1 in the process of MACC1-driven metastasis. MACC1 is a prognostic indicator for patient metastasis formation and metastasis-free survival. MACC1 controls gene transcription, promotes motility, invasion and proliferation of colon cancer cells in vitro, and causes tumor growth and metastasis in mice. Methods: By using yeast-two-hybrid assay, mass spectrometry, co-immunoprecipitation and peptide array we analyzed GIPC1 protein binding partners, by using the MACC1 gene promoter and chromatin immunoprecipitation and electrophoretic mobility shift assay we probed for GIPC1 as transcription factor. We employed GIPC1/MACC1-manipulated cell lines for in vitro and in vivo analyses, and we probed the GIPC1/MACC1 impact using human primary colorectal cancer (CRC) tissue. Results: We identified MACC1 and its paralogue SH3BP4 as protein binding partners of the protein GIPC1, and we also demonstrated the binding of GIPC1 as transcription factor to the MACC1 promoter (TSS to -60 bp). GIPC1 knockdown reduced endogenous, but not CMV promoter-driven MACC1 expression, and diminished MACC1-induced cell migration and invasion. GIPC1 suppression reduced tumor growth and metastasis in mice intrasplenically transplanted with MACC1-overexpressing CRC cells. In human primary CRC specimens, GIPC1 correlates with MACC1 expression and is of prognostic value for metastasis formation and metastasis-free survival. Combination of MACC1 and GIPC1 expression improved patient survival prognosis, whereas SH3BP4 expression did not show any prognostic value. Conclusions: We identified an important, dual function of GIPC1 - as protein interaction partner and as transcription factor of MACC1 - for tumor progression and cancer metastasis.
An Experimental Study of Class Imbalance in Federated Learning
Creators: name: Xiao, C.
name: Wang, S.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Federated learning is a distributed machine learning paradigm that trains a global model for prediction based on a number of local models at clients while local data privacy is preserved. Class imbalance is believed to be one of the factors that degrades the global model performance. However, there has been very little research on if and how class imbalance can affect the global performance. class imbalance in federated learning is much more complex than that in traditional non-distributed machine learning, due to different class imbalance situations at local clients. Class imbalance needs to be re-defined in distributed learning environments. In this paper, first, we propose two new metrics to define class imbalance -- the global class imbalance degree (MID) and the local difference of class imbalance among clients (WCS). Then, we conduct extensive experiments to analyze the impact of class imbalance on the global performance in various scenarios based on our definition. Our results show that a higher MID and a larger WCS degrade more the performance of the global model. Besides, WCS is shown to slow down the convergence of the global model by misdirecting the optimization.
Metabolomic signatures of intestinal colonization resistance against Campylobacter jejuni in mice
Creators: name: Shayya, Nizar W.
name: Bandick, Rasmus
name: Busmann, Lia V.
name: Mousavi, Soraya
name: Bereswill, Stefan
name: Heimesaat, Markus M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: Campylobacter jejuni
subject: colonization resistance
subject: gut microbiota
subject: metabolome
subject: bile acids
subject: amino acids
subject: fatty acids
subject: host-pathogen interactions
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: Campylobacter jejuni stands out as one of the leading causes of bacterial enteritis. In contrast to humans, specific pathogen-free (SPF) laboratory mice display strict intestinal colonization resistance (CR) against C. jejuni, orchestrated by the specific murine intestinal microbiota, as shown by fecal microbiota transplantation (FMT) earlier. Methods: Murine infection models, comprising SPF, SAB, hma, and mma mice were employed. FMT and microbiota depletion were confirmed by culture and culture-independent analyses. Targeted metabolome analyses of fecal samples provided insights into the associated metabolomic signatures. Results: In comparison to hma mice, the murine intestinal microbiota of mma and SPF mice (with CR against C. jejuni) contained significantly elevated numbers of lactobacilli, and Mouse Intestinal Bacteroides, whereas numbers of enterobacteria, enterococci, and Clostridium coccoides group were reduced. Targeted metabolome analysis revealed that fecal samples from mice with CR contained increased levels of secondary bile acids and fatty acids with known antimicrobial activities, but reduced concentrations of amino acids essential for C. jejuni growth as compared to control animals without CR. Discussion: The findings highlight the role of microbiota-mediated nutrient competition and antibacterial activities of intestinal metabolites in driving murine CR against C. jejuni. The study underscores the complex dynamics of host-microbiota-pathogen interactions and sets the stage for further investigations into the mechanisms driving CR against enteric infections.
title: The effective swept volume of a bottom trawl
Creators: name: Handegard, Nils Olav
name: Tjøstheim, Dag
Publisher: name: ASC 2004 - R - Theme session
Year: 2024
Subjects: Fisheries and aquaculture
Technologies and data

description: No abstracts are to be cited without prior reference to the author.The reaction of individual fish towards an approaching trawling vessel has previously been measured using target-tracking methods. In this paper these measured velocities are fitted to a deterministic mean behaviour model and a diffusion-advection model taking the random component into account. The output of the diffusion-advection model is used to estimate the probability of a fish to be caught by the bottom trawl. For typical depths in the Barents Sea, 200 - 350 m, and for immature Cod feeding on capelin, a mean fishing height of about 10 metres is found, and the effect of horizontal herding from the warp is shown. The effect of random fish movement is visualised by the different results from the two models.
Towards an informed research agenda for the field of personality disorders by experts with lived and living experience and researchers
Creators: name: Renneberg, Babette
name: Hutsebaut, Joost
name: Berens, Ann
name: De Panfilis, Chiara
name: Bertsch, Katja
name: Kaera, Andres
name: Kramer, Ueli
name: Schmahl, Christian
name: Swales, Michaela
name: Sieg, Julia
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Public and patient involvement
subject: Experts with lived experience
subject: Personality disorder
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: Background We describe a collection of themes for a research agenda for personality disorders that was originally formulated for the ESSPD Borderline Congress in 2022. Methods Experts with lived and living experience (EE), researchers and clinicians met virtually, exchanged ideas and discussed research topics for the field of personality disorders. The experts - patients, relatives, significant others - named the topics they thought most relevant for further research in the field. These topics were presented at the ESPPD conference in October 2022. Results The five top themes were: 1. Prevention, early detection and intervention, 2. Recovery beyond symptom improvement, 3. Involvement of relatives in treatment, 4. Gender dysphoria, and 5. Stigma. Conclusions In general, the topics reflect current issues and changes in societal values. Overarching aims of research on these topics are the improvement of social participation and integration in society, better dissemination of research, and better information of the general public and political stakeholders.
title: Discrimination of Single Fish by Species Based on Multi-frequency Split-beam Measurements
Creators: name: Thomas, Rebecca E.
name: Mulligan, Tim
name: Degan, Don
name: Kieser, Robert
name: Burwen, Debby L.
name: Fleischer, Guy W.
Publisher: name: ASC 2004 - R - Theme session
Year: 2024
Subjects: Fisheries and aquaculture
Technologies and data

description: No abstracts are to be cited without prior reference to the author.Multi-frequency echosounder measurements have been used for some time to differentiate between plankton assemblages and more recently between fish aggregations. This paper explores using multi-frequency techniques and behavioral descriptors to discriminate between sockeye and chinook salmon in the Kenai River, Alaska. Four EK60 split-beam sounders at frequencies of 70, 120, 200 and 400 kHz were used. The 7 degree transducers were mounted on a single plate and the assembly was deployed with near horizontal aim in the river. Appropriate target spheres were used to individually aim the transducers into the same sample volume. Transmissions were simultaneous to assure that the fish would be ensonified with the four frequencies at the same time. The shortest available pulse durations (64 μs for the 120, 200, and 400 kHz sounders, and 128 μs for the 70 kHz sounder) were used to obtain additional information by resolving the fish acoustically. Fish in side aspect were at least twice as wide as the pulse length, resulting in rich echo shapes that were encapsulated using several echo shape parameters. Free swimming and tethered sockeye and chinook were observed in the Kenai River. Concurrent fish behavior observations of tethered fish were made with a high-resolution dual frequency identification sonar (DIDSON). Sonar images and echo shape parameters from tethered fish were compared to link swimming behavior with echo shape characteristics and to explore the potential usefulness of the echo shape parameters for species discrimination.
Myrrh protects against IL-13-induced epithelial barrier breakdown in HT-29/B6 cells
Creators: name: Hader, Helena
name: Hering, Nina A.
name: Schulzke, Jörg-Dieter
name: Bücker, Roland
name: Rosenthal, Rita
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: Myrrh
subject: tight junction
subject: barrier function
subject: claudin
subject: tricellulin
subject: apoptosis
subject: STAT pathway
subject: inflammatory bowel disease
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The oleoresin myrrh has been used for centuries as an anti-inflammatory remedy for a variety of diseases and is said to have a protective effect on the intestinal epithelium. An intact epithelial barrier function is the prerequisite for a healthy gut. Inflammatory and infectious diseases of the intestine, in particular, lead to barrier impairment resulting in leak-flux diarrhea and mucosal immune responses. Therefore, the aim of the present study was to investigate the protective effect of myrrh in an experimental inflammatory situation, namely, under the influence of IL-13, one of the key cytokines in ulcerative colitis. We used human intestinal epithelial HT-29/B6 cell monolayers for functional and molecular assessment of the epithelial barrier under IL-13 and myrrh treatment. IL-13 induced a loss in barrier function that was fully restored with myrrh treatment, as shown by transepithelial electrical resistance measurements. The molecular correlate of the IL-13-mediated barrier dysfunction could be assigned to an upregulation of the channel-forming tight junction (TJ) protein claudin-2 and to a subcellular redistribution of the TJ protein tricellulin, loosening the sealing of tricellular TJs. Moreover, IL-13 exposure leads to an increase in the number of apoptotic cells, contributing to the leak pathway of barrier dysfunction. Myrrh protected against changes in TJ deregulation and decreased the elevated apoptotic ratio under IL-13. The protective effects are mediated through the inhibition of the STAT3 and STAT6 pathway. In conclusion, our results demonstrate that myrrh exhibits antagonizing effects against IL-13-induced barrier impairment in a human intestinal cell model. These data suggest the use of myrrh as a promising option in the treatment of inflammatory bowel disease.
Test Comparison of Precision Xtra® and Ketostix® for Ketosis in Dairy Cows
Creators: name: Burke, C. M.
name: Rapheal, W.
name: Leslie, K. E.
name: Neuder, L. M.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2008

description: Ketosis is a common disease of periparturient dairy cows. Ketosis is defined as an increased concentration of beta-hydroxybutyric acid (BHBA) in the serum. There is strong evidence that cows with mild ketonemia (above approximately 1.1-1.4mmol/l) are at an increased risk of other disease (e.g. displaced abomasum), decreased milk production and infertility. Diagnosing ketosis is important because it has a financial cost and at the herd level, reflects feeding and management. The objective of this study was to assess the accuracy of a newly available BHBA assay (Precision Xtra®), marketed for human diabetic patients, by comparison to the gold standard test. This new device has potential to be a quality cows-side test for monitoring subclinical ketosis in dairy cattle. An additional objective was to assess the accuracy of the Ketostix® test.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2008
Accuracy of power spectra in dissipationless cosmological simulations
Creators: name: Maleubre, Sara
name: Eisenstein, Daniel
name: Garrison, Lehman H.
name: Joyce, Michael
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We exploit a suite of large \emph{N}-body simulations (up to N=$4096^3$) performed with \Abacus, of scale-free models with a range of spectral indices $n$, to better understand and quantify convergence of the matter power spectrum. Using self-similarity to identify converged regions, we show that the maximal wavenumber resolved at a given level of accuracy increases monotonically as a function of time. At the 1\% level it starts at early times from a fraction of $k_Λ$, the Nyquist wavenumber of the initial grid, and reaches at most, if the force softening is sufficiently small, $\sim 2-3 k_Λ$ at the very latest times we evolve to. At the $5\%$ level, accuracy extends up to wavenumbers of order $5k_Λ$ at late times. Expressed as a suitable function of the scale-factor, accuracy shows a very simple $n$-dependence, allowing a extrapolation to place conservative bounds on the accuracy of \emph{N}-body simulations of non-scale free models like LCDM. We note that deviations due to discretization in the converged range are not well modelled by shot noise, and subtracting it in fact degrades accuracy. Quantitatively our findings are broadly in line with the conservative assumptions about resolution adopted by recent studies using large cosmological simulations (e.g. Euclid Flagship) aiming to constrain the mildly non-linear regime. On the other hand, we remark that conclusions about small scale clustering (e.g. concerning the validity of stable clustering) obtained using PS data at wavenumbers larger than a few $k_Λ$ may need revision in light of our convergence analysis.
description: 14 pages, 10 figures, version to match published version. Additional subsection in Shot noise and discreteness effects
Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis
Creators: name: Pappritz, Kathleen
name: Puhl, Sarah-Lena
name: Matz, Isabel
name: Brauer, Erik
name: Shia, Yi Xuan
name: El-Shafeey, Muhammad
name: Koch, Suzanne E.
name: Miteva, Kapka
name: Mucha, Christin
name: Duda, Georg N.
name: Petersen, Ansgar
name: Steffens, Sabine
name: Tschöpe, Carsten
name: Van Linthout, Sophie
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: aging
subject: sex
subject: cardiac fibroblasts
subject: cardiosplenic axis
subject: monocytes
subject: fibrosis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Age and sex are prominent risk factors for heart failure and determinants of structural and functional changes of the heart. Cardiac fibroblasts (cFB) are beyond their task as extracellular matrix-producing cells further recognized as inflammation-supporting cells. The present study aimed to evaluate the impact of sex and age on the inflammatory potential of cFB and its impact on the cardiosplenic axis and cardiac fibrosis. Materials: Left ventricles (LV) of 3- and 12-months old male and female C57BL/6J mice were harvested for immunohistochemistry, immunofluorescence and cFB outgrowth culture and the spleen for flow cytometry. LV-derived cFB and respective supernatants were characterized. Results: LV-derived cFB from 3-months old male mice exhibited a higher inflammatory capacity, as indicated by a higher gene expression of CC-chemokine ligand (CCL) 2, and CCL7 compared to cFB derived from 3-months old female mice. The resulting higher CCL2/chemokine C-X3-C motif ligand (Cx3CL1) and CCL7/Cx3CL1 protein ratio in cell culture supernatants of 3-months old male vs. female cFB was reflected by a higher migration of Ly6Chigh monocytes towards supernatant from 3-months old male vs. female cFB. In vivo a lower ratio of splenic pro-inflammatory Ly6Chigh to anti-inflammatory Ly6Clow monocytes was found in 3-months old male vs. female mice, suggesting a higher attraction of Ly6Chigh compared to Ly6Clow monocytes towards the heart in male vs. female mice. In agreement, the percentage of pro-inflammatory CD68+ CD206- macrophages was higher in the LV of male vs. female mice at this age, whereas the percentage of anti-inflammatory CD68+ CD206+ macrophages was higher in the LV of 3-months old female mice compared to age-matched male animals. In parallel, the percentage of splenic TGF-beta+ cells was higher in both 3- and 12-months old female vs. male mice, as further reflected by the higher pro-fibrotic potential of female vs. male splenocytes at both ages. In addition, female mice displayed a higher total LV collagen content compared to age-matched male mice, whereby collagen content of female cFB was higher compared to male cFB at the age of 12-months. Conclusion: Age- and sex-dependent differences in cardiac fibrosis and inflammation are related to age- and sex-dependent variations in the inflammatory properties of cardiac fibroblasts.
Robust spin-polarized midgap states at step edges of topological crystalline insulators
Creators: name: Sessi, Paolo
name: Di Sante, Domenico
name: Szczerbakow, Andrzej
name: Glott, Florian
name: Wilfert, Stefan
name: Schmidt, Henrik
name: Bathon, Thomas
name: Dziawa, Piotr
name: Greiter, Martin
name: Neupert, Titus
name: Sangiovanni, Giorgio
name: Story, Tomasz
name: Thomale, Ronny
name: Bode, Matthias
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Topological crystalline insulators are materials in which the crystalline symmetry leads to topologically protected surface states with a chiral spin texture, rendering them potential candidates for spintronics applications. Using scanning tunneling spectroscopy, we uncover the existence of one-dimensional (1D) midgap states at odd-atomic surface step edges of the three- dimensional topological crystalline insulator (Pb,Sn)Se. A minimal toy model and realistic tight- binding calculations identify them as spin-polarized flat bands connecting two Dirac points. This non-trivial origin provides the 1D midgap states with inherent stability and protects them from backscattering. We experimentally show that this stability results in a striking robustness to defects, strong magnetic fields, and elevated temperature.
Towards Stochastic Fault-tolerant Control using Precision Learning and Active Inference
Creators: name: Baioumy, Mohamed
name: Pezzato, Corrado
name: Corbato, Carlos Hernandez
name: Hawes, Nick
name: Ferrari, Riccardo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Robotics (cs.RO)
subject: Machine Learning (cs.LG)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This work presents a fault-tolerant control scheme for sensory faults in robotic manipulators based on active inference. In the majority of existing schemes, a binary decision of whether a sensor is healthy (functional) or faulty is made based on measured data. The decision boundary is called a threshold and it is usually deterministic. Following a faulty decision, fault recovery is obtained by excluding the malfunctioning sensor. We propose a stochastic fault-tolerant scheme based on active inference and precision learning which does not require a priori threshold definitions to trigger fault recovery. Instead, the sensor precision, which represents its health status, is learned online in a model-free way allowing the system to gradually, and not abruptly exclude a failing unit. Experiments on a robotic manipulator show promising results and directions for future work are discussed.
description: Presented at the International Workshop on Active Inference (IWAI) 2021; 11 pages, 3 figures
Apparent Efficacy of Blanket Clinical Mastitis Treatment
Creators: name: Roberson, J. R.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2008

description: Efficacy of a mastitis treatment depends largely upon the mastitis agent. Yet, a standard mastitis treatment protocol is used on many dairies to decrease the risk of drug residues in milk and because of logistical problems associated with obtaining culture results in a timely manner. However, blanket mastitis treatment regimens result in cases of clinical mastitis being improperly treated. The hypothesis is that over 50% of clinical mastitis cases are treated inappropriately.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2008
Field Evaluation of the Finnzyme Mastitis Pathogen Detection System for Cows and Quarters Infected with Staphylococcus aureus
Creators: name: Friendship, C.
name: Kelton, D.
name: Leslie, K.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2008

description: Staphylococcus aureus, a contagious pathogen, is one of the most important etiological agents of chronic, clinical and subclinical mastitis (Studer et al, 2008). S. aureus damages milk-producing tissue and significantly decreases milk production. Since damage is minimal and reversible in early infection and this infection is contagious, it would be advantageous to have a reliable and sensitive detection system in place to identify early infections in order that treatment and management to prevent spread could occur. Subclinical S. aureus infections are usually associated with elevated somatic cell counts (SCC) and confirmed by bacteriologic culture. Some significant limitations to the traditional culturebased systems for identifying S. aureus exist. Sears et al (1990) determined that even under ideal conditions the sensitivity of culturing quarter samples only reached 74.5%. Also, due to the cyclical nature of the shedding of S. aureus, the culture of samples collected over multiple days is necessary to conclusively establish the S. aureus infection status of a quarter. A real-time PCR-based reagent kit for bovine mastitis has been developed by Finnzymes. While more expensive than traditional culture-based systems, this system has a distinct advantage in that it can be applied to metered milk samples collected for general milk recording purposes by most Dairy Herd Improvement (DHI) organizations. The Finnzymes test system has been shown to be accurate in the detection of most mastitis-associated pathogens in laboratory testing. It has been proposed that this PCR-based test may be more convenient and more accurate than traditional culture-based systems in identifying cows with subclinical S. aureus infections. The first objective of this pilot project is to measure the agreement between a PCR-based diagnostic system and a culture-based system for identifying S. aureus infected cows and quarters. The second objective is to determine the cause(s) of disagreement that may occur between the two test systems.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2008
Fresh Cow Monitoring on Day Three Post-partum and Lactation Milk Production
Creators: name: Anderson, K. L.
name: Correa, M. T.
name: Allen, A.
name: Rodriguez, R.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2008

description: Assessment of udder health is one component of fresh cow monitoring programs. Both on-farm efforts and research studies have considered the use of milk culture, the California Mastitis Test (CMT), and/or somatic cell counts for monitoring udder health post-partum. The purpose of this study was to determine if various measures of udder health evaluated on day 3 post-partum were associated with lactational milk production.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2008
Associations of loneliness with mental health and with social and physical activity among university students in Germany: results of the COVID-19 German student well-being study (C19 GSWS)
Creators: name: Wenig, Vanessa
name: Heumann, Eileen
name: Stock, Christiane
name: Busse, Heide
name: Negash, Sarah
name: Pischke, Claudia R.
name: Heinrichs, Katherina
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: loneliness
subject: mental health
subject: university students
subject: COVID-19 pandemic
subject: depressive symtoms
subject: anxiety
subject: physical activity
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: University students are at high risk for loneliness with a potential negative impact on health. The COVID-19 measures disrupted students' academic routine and social life, which might have affected their perception of loneliness. This study investigated the prevalence of perceived loneliness among university students in Germany during the COVID-19 pandemic and its associations with mental health, behavioral outcomes, and sociodemographic characteristics. Methods: COVID-19 German student well-being study (C19 GSWS) collected data from five German universities from October 27th to November 14th, 2021, resulting in a sample of 7,203 respondents. Associations of loneliness with depressive symptoms, anxiety, social and physical activity, as well as sociodemographic characteristics, were analyzed using multivariable logistic regressions. Results: A total of 20.6% of students reported loneliness. Students with depressive or anxiety symptoms had more than eight- or sixfold odds, respectively, for reporting loneliness (depressive symptoms: OR = 8.29; 95% CI: 7.21-9.52; anxiety: OR = 6.48; 95% CI: 5.65-7.43) compared with students who did not report any symptoms. Students who were less physically active were more likely to experience loneliness compared with students who were more physically active (no moderate physical activity: OR = 1.39; 95% CI: 1.21-1.59; no vigorous physical activity: OR = 1.19; 95% CI: 1.04-1.36). We found no association between loneliness and social activity. However, loneliness was associated with being single (OR = 2.93; 95% CI: 2.55-3.36), living alone (OR = 1.31; 95% CI: 1.13-1.52), or having a temporary residency status in Germany (OR = 2.24; 95% CI: 1.65-3.04). Conclusion: Our findings highlight the importance of loneliness as a relevant factor associated with health. Further research is needed to determine potential protective factors to tackle loneliness and to investigate how study conditions at higher education institutions may affect students' perceived loneliness.
"That branch of the Lake of Como…": Developing a New Resource for the Analysis of I Promessi Sposi and its Historical Translations
Creators: name: Sprugnoli, Rachele
name: Marco, Sartor
Publisher: name: Zenodo
Year: 2023
Subjects: computational linguistics
literature
translation studies
parallel corpus

description: Presentation given at the Ninth Italian Conference on Computational Linguistics (CLiC-it 2023): https://clic2023.ilc.cnr.it/

Questa pubblicazione è stata realizzata da ricercatrice con contratto di ricerca cofinanziato dall’Unione europea - PON Ricerca e Innovazione 2014-2020 ai sensi dell’art. 24, comma 3, lett. a, della Legge 30 dicembre 2010, n. 240 e s.m.i. e del D.M. 10 agosto 2021 n. 1062. Questa ricerca è stata anche finanziata dall’Università degli Studi di Parma attraverso l’azione Bando di Ateneo 2022 per la ricerca co-finanziata dal MUR-Ministero dell’Università e della Ricerca - D.M. 737/2021 - PNR - PNRR - NextGenerationEU.
Influence of Time, Temperature and Starting Bacteria Load Parameters on the Quality of Raw Bulk Tank Milk
Creators: name: Melek, S. R. A.
name: Keefe, G.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2008

description: Higher quality raw milk produces superior milk products that have a preferred position in the marketplace. The production of high quality milk products requires that milk be harvested with the minimum of bacterial contamination, and stored at low temperatures for the shortest time period practical before processing. These three factors (low start bacterial load, low storage temperature and short storage time) inhibit bacterial growth, which is important to maintain quality and to increase shelf life. The objective of this study was to examine the relative importance of these factors, and interactions between the factors, on end bacterial burden.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2008
Noncommutative Blackwell-Ross martingale inequality
Creators: name: Talebi, Ali
name: Moslehian, Mohammad Sal
name: Sadeghi, Ghadir
Publisher: name: arXiv
Year: 2017
Subjects: subject: Operator Algebras (math.OA)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: Primary 46L53, Secondary 46L10, 47A30

description: We establish a noncommutative Blackwell--Ross inequality for supermartingales under a suitable condition which generalize Khan's works to the noncommutative setting. We then employ it to deduce an Azuma-type inequality.
description: 9 pages, to appear in Infin. Dimens. Anal. Quantum Probab. Relat. Top