cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
IN-SILICO MOLECULAR DOCKING STUDY OF AFZELIN AND ITS DERIVATIVES AGAINST 6M0J FOR TREATMENT OF COVID-19
Creators: name: Bhuia, Md. Shimul
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 310201
subject: Bioinformatic methods development

description: The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated in the Chinese city of Wuhan and has been spread worldwide. In a life-threatening situation, where there is no specific and licensed anti-COVID-19 drug of choice available. Afzelin (AF) a natural compound from Zanthoxylum bungeanum, having antiviral activity against SARS-CoV-2. SARS-Cov-2 enters into the host cell through ACE2 and has a significant binding affinity to ACE2. The higher binding affinity and adequate pharmacokinetics of Afzelin have triggered us to design several new chemical entities for the discovery and development of new compounds against SARS-CoV-2. In this study, we designed ligand-based drug strategies to select potential target molecules to be an effective inhibitor of protein. AF and some of its derivative es (AF-Cl, AF-Br, AF-CF3, AF-OCH2CH3, AF-OCH2CF3) were screened against ACE2 (PDB ID: 6M0J), RNA dependent RNA polymerase (PDB ID: 7BTF), the main protease (PDB ID: 6LU7), PLpro (PDB ID: 7KOL) crystal structure of the protein. Molecular docking was performed under AutoDockVina in PyRx platform to reveal noble scaffolds having the highest binding affinity-9.2 for the modified drug AF-CF3 than the original drug AF (-8.3) against 6M0J. Molecular orbital theory and discovery studio visualizer v4.5.0.15071 were applied to get thermodynamically more stable and chemically reactive compounds to find the nonbonding interactions and binding sites of the proteins. The hydrogen bond, pi-alkyl bonds, preADMET and admetSAR@LMMD online database have been utilized to predict the pharmacokinetic properties and toxicity of Afzelin and its derivatives. According to our findings, we proposed AF-CF3, will be a noble potential inhibitor against ACE2 for the treatment of Covid-19.
Gapped electron liquid state in the symmetric Anderson lattice, Kondo insulator state
Creators: name: Karnaukhov, Igor N.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The Kondo insulator state (KIS) realized in the symmetric Anderson model at half filling is studied in the framework of a mean field approach. It is shown that the state of the Kondo insulator is realized in a lattice with a double cell and a gapped electron liquid behaves like a gapless Majorana spin liquid. The local moments of d-electrons form a static $Z_2$-field in which band electrons move. The gap value in the quasi-particle excitations spectrum decreases with increasing an external magnetic field and closes at its critical value. The behavior of an electron liquid is studied for an arbitrary dimension of the model. The proposed approach leads to the description of KIS without the need to resort to artificial symmetry breaking to alternative understanding of the physical nature of this phase state.
description: 7 pages, 4 figures
Poster reflection of my internship abroad
Creators: name: Auner, Nadine
name: Schüssler, Renate
Publisher: name: Univ. Bielefeld, Fakultät für Erziehungswissenschaft
Year: 2023
Subjects: subject: 370

description: This poster can be used by teacher training students to reflect their internship abroad in a seminar context. It gives an insight into their internship and students are asked to link their experiences abroad to their preparatory seminar and their later job as teachers. The topics can be adapted depending on the internship. The poster also serves as an exchange between students who have their stay abroad ahead of them and students wo have already completed their stay abroad.
Algebraic weak factorisation systems II: categories of weak maps
Creators: name: Bourke, John
name: Garner, Richard
Publisher: name: arXiv
Year: 2014
Subjects: subject: Category Theory (math.CT)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 18A32, 55U35

description: We investigate the categories of weak maps associated to an algebraic weak factorisation system (AWFS) in the sense of Grandis-Tholen. For any AWFS on a category with an initial object, cofibrant replacement forms a comonad, and the category of (left) weak maps associated to the AWFS is by definition the Kleisli category of this comonad. We exhibit categories of weak maps as a kind of "homotopy category", that freely adjoins a section for every "acyclic fibration" (=right map) of the AWFS; and using this characterisation, we give an alternate description of categories of weak maps in terms of spans with left leg an acyclic fibration. We moreover show that the 2-functor sending each AWFS on a suitable category to its cofibrant replacement comonad has a fully faithful right adjoint: so exhibiting the theory of comonads, and dually of monads, as incorporated into the theory of AWFS. We also describe various applications of the general theory: to the generalised sketches of Kinoshita-Power-Takeyama, to the two-dimensional monad theory of Blackwell-Kelly-Power, and to the theory of dg-categories.
description: 30 pages, final journal version
A Mapping Literature Review of Medical Cannabis Clinical Outcomes and Quality of Evidence in Approved Conditions in the USA from 2016 to 2019
Creators: name: Morris, E.J.
name: Joseph, V.
name: Adkins, L.
name: Goodin, A.
name: Hincapie-Castillo, J.M.
name: Zhang, Y.
name: Stetten, N.E.
name: Sajdeya, R.
name: Shen, Y.
name: Costales, B.
name: Winterstein, A.G.
name: Keshwani, S.
name: Alipour-Haris, G.
name: Jugl, S.
name: Okpeku, A.
Publisher: name: S. Karger AG
Year: 2021

description: In 2017, a National Academies of Sciences, Engineering, and Medicine (NASEM) report comprehensively evaluated the body of evidence regarding cannabis health effects through the year 2016. The objectives of this study are to identify and map the most recently (2016-2019) published literature across approved conditions for medical cannabis and to evaluate the quality of identified recent systematic reviews, published following the NASEM report. Following the literature search from 5 databases and consultation with experts, 11 conditions were identified for evidence compilation and evaluation: amyotrophic lateral sclerosis, autism, cancer, chronic noncancer pain, Crohn's disease, epilepsy, glaucoma, human immunodeficiency virus/AIDS, multiple sclerosis (MS), Parkinson's disease, and posttraumatic stress disorder. A total of 198 studies were included after screening for condition-specific relevance and after imposing the following exclusion criteria: preclinical focus, non-English language, abstracts only, editorials/commentary, case studies/series, and non-U.S. study setting. Data extracted from studies included: study design type, outcome definition, intervention definition, sample size, study setting, and reported effect size. Few completed randomized controlled trials (RCTs) were identified. Studies classified as systematic reviews were graded using the Assessing the Methodological Quality of Systematic Reviews-2 tool to evaluate the quality of evidence. Few high-quality systematic reviews were available for most conditions, with the exceptions of MS (9 of 9 graded moderate/high quality; evidence for 2/9 indicating cannabis improved outcomes; evidence for 7/9 indicating cannabis inconclusive), epilepsy (3 of 4 graded moderate/high quality; 3 indicating cannabis improved outcomes; 1 indicating cannabis inconclusive), and chronic noncancer pain (12 of 13 graded moderate/high quality; evidence for 7/13 indicating cannabis improved outcomes; evidence from 6/7 indicating cannabis inconclusive). Among RCTs, we identified few studies of substantial rigor and quality to contribute to the evidence base. However, there are some conditions for which significant evidence suggests that select dosage forms and routes of administration likely have favorable risk-benefit ratios (i.e., epilepsy and chronic noncancer pain). The body of evidence for medical cannabis requires more rigorous evaluation before consideration as a treatment option for many conditions, and evidence necessary to inform policy and treatment guidelines is currently insufficient for many conditions.
Impurity reveals distinct operational phases in quantum thermodynamic cycles
Creators: name: Prakash, Aditya
name: Kumar, Abhishek
name: Benjamin, Colin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: We analyze the effect of impurity on the work output and efficiency of quantum Otto and quantum Carnot heat cycles, modeled as a single quantum particle in an infinite square well (ISW) potential, which is the working substance. We solve this quantum mechanical system perturbatively up to first and second order in strength of the impurity for strong and weak coupling regimes, respectively. We derive the analytical expressions of work and efficiency for the strong coupling regime to the first order in the strength parameter. The threshold value of the strength parameter in weak coupling is obtained up to which the numerical result agrees with the perturbative result for a repulsive and attractive impurity. To our surprise, an embedded impurity unlocks new operational phases in the system, such as a quantum heat engine, quantum refrigerator, and quantum cold pump. In addition, the efficiency of the quantum Otto heat engine is seen to reach Carnot efficiency for some parameter regimes. The cooling power and coefficient of performance of the quantum refrigerator and quantum cold pump are non-trivially affected by the impurity.
description: 15 pages, 16 figures, accepted for publication in Phys. Rev. E
Constraints on dark radiation from cosmological probes
Creators: name: Rossi, Graziano
name: Yeche, Christophe
name: Palanque-Delabrouille, Nathalie
name: Lesgourgues, Julien
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present joint constraints on the number of effective neutrino species N_eff and the sum of neutrino masses M_nu, based on a technique which exploits the full information contained in the one-dimensional Lyman-Alpha forest flux power spectrum, complemented by additional cosmological probes. In particular, we obtain N_eff=2.91(+0.21)(-0.22) (95% CL) and M_nu<0.15 eV (95% CL) when we combine BOSS Lyman-Alpha forest data with CMB (Planck+ACT+SPT+WMAP polarization) measurements, and N_eff=2.88(+0.20)(-0.20) (95% CL) and M_nu<0.14 eV (95% CL) when we further add baryon acoustic oscillations. Our results provide evidence for the Cosmic Neutrino Background from N_eff~3 (N_eff=0 is rejected at more than 14 sigma), and rule out the possibility of a sterile neutrino thermalized with active neutrinos (i.e., N_eff=4) - or more generally any decoupled relativistic relic with Delta N_eff ~ 1 - at a significance of over 5 sigma, the strongest bound to date, implying that there is no need for exotic neutrino physics in the concordance LCDM model.
description: 12 pages, 5 figures, 1 table, expanded version, PRD in press
Five Years of United States Naval Observatory's 50% Time with The Very Long Baseline Array
Creators: name: Johnson, Megan
Publisher: name: Zenodo
Year: 2022

description: We present an overview and status update of the past five years of the United States Naval Observatory's (USNO's) 50% timeshare allocation on the Very Long Baseline Array (VLBA). Beginning in January 2017, the USNO began a 50% timeshare agreement on the VLBA primarily for maintaining, improving, and monitoring the International Celestial Reference Frame (ICRF). USNO uses the VLBA for many scientific applications including measuring the precise positions of quasars that comprise the ICRF, imaging quasars to study source structure and determining quasar peak and integrated radio flux densities. In 2018, the USNO began a research project called the Fundamental AGN Monitoring Experiment (FRAMEx) to monitor various aspects of AGNs as they relate to the Celestial Reference Frame. The initial FRAMEx investigation is a volume-complete sample of Active Galactic Nuclei (AGN) systems with simultaneous VLBA and X-ray observations. The first results from this project will also be presented.
A call to look beyond prescription opioid supply-side restrictions and include health equity when predicting opioid policy effectiveness
Creators: name: Goodin, A.
name: Hincapie-Castillo, J.M.
Publisher: name: Elsevier Ltd
Year: 2021

description: We read with interest the study by Rao and colleagues on opioid policy effectiveness, which extends their previous modeling efforts to predict opioid-related overdose, life-years, and QALYs. This work presents a useful framework from which to investigate policy effectiveness.
Homogeneous spaces, curvature and cohomology
Creators: name: Herrmann, Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: Primary 53C20, Secondary 53C30

description: We give new counterexamples to a question of Karsten Grove, whether there are only finitely many rational homotopy types among simply connected manifolds satisfying the assumptions of Gromov's Betti number theorem. Our counterexamples are homogeneous Riemannian manifolds, in contrast to previous ones. They consist of two families in dimensions 13 and 22. Both families are nonnegatively curved with an additional upper curvature bound and differ already by the ring structure of their cohomology rings with complex coefficients. The 22-dimensional examples also admit almost nonnegative curvature operator with respect to homogeneous metrics.
description: 11 pages; minor changes, accepted version
What Your Wearable Devices Revealed About You and Possibilities of Non-Cooperative 802.11 Presence Detection During Your Last IPIN Visit
Creators: name: Bravenec, Tomas
name: Torres-Sospedra, Joaquín
name: Gould, Michael
name: Fryza, Tomas
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: The focus on privacy-related measures regarding wireless networks grew in last couple of years. This is especially important with technologies like Wi-Fi or Bluetooth, which are all around us and our smartphones use them not just for connection to the internet or other devices, but for localization purposes as well. In this paper, we analyze and evaluate probe request frames of 802.11 wireless protocol captured during the 11th international conference on Indoor Positioning and Indoor Navigation (IPIN) 2021. We explore the temporal occupancy of the conference space during four days of the conference as well as non-cooperatively track the presence of devices in the proximity of the session rooms using 802.11 management frames, with and without using MAC address randomization. We carried out this analysis without trying to identify/reveal the identity of the users or in any way reverse the MAC address randomization. As a result of the analysis, we detected that there are still many devices not adopting MAC randomization, because either it is not implemented, or users disabled it. In addition, many devices can be easily tracked despite employing MAC randomization.
description: 7 pages, 7 figures, submitted to IPIN2022 conference
Socioeconomic and Demographic Characteristics of US Adults Who Purchase Prescription Drugs from Other Countries
Creators: name: Hong, Y.-R.
name: Segal, R.
name: Mainous, A.G., III
name: Hincapie-Castillo, J.M.
name: Xie, Z.
Publisher: name: American Medical Association
Year: 2020

description: Importance: Little is known about the current use of imported drugs and the factors associated with individual purchase of medications outside the US. Objective: To evaluate the proportion of the US adult population that purchases medications in other countries and the patient factors associated with the behavior. Design, Setting, and Participants: This retrospective cross-sectional study used data from the 2015-2017 National Health Interview Survey. The study sample included 61238 individuals 18 years or older who reported use of prescribed medication by a physician or other practitioner. Data analysis was performed in November 2019. Main Outcomes and Measures: Self-reported experience of purchasing prescription drugs from countries outside the US in the past 12 months. Internet use behaviors for health care included searches for health information and filling of a prescription online. Medication-taking behaviors included skipping or delaying filling a prescription and using alternative therapies to save money. Survey design-adjusted analysis was used to estimate and compare characteristics between those who purchased medications outside the US and those did not. Multivariable logistic regression was fitted to examine the association of medication purchases with internet use and medication-taking behavior factors. Results: Among 61238 US adults taking prescription medications (mean [SD] age, 50.5 [18.5] years; 56.5% female; 70.8% white), the estimated prevalence of purchasing of medication outside the US was 1.5% (95% CI, 1.4%-1.7%; 2.3 million US individuals). Those who purchased medications outside the US were more likely to be older (age >64 years; adjusted odds ratio [aOR], 1.68; 95% CI, 1.24-2.29), to be from Hispanic (aOR, 1.70; 95% CI, 1.23-2.35) or immigrant populations (aOR, 3.20; 95% CI, 2.44-4.20), and to have higher educational attainment (bachelor's degree; aOR, 1.79; 95% CI, 1.27-2.54), lower family income (low income; aOR, 1.41; 95% CI, 1.06-1.87), and lack of insurance (aOR, 3.14; 95% CI, 2.33-4.21). Data analyses indicated that online health information-seeking behavior (aOR, 1.62; 95% CI, 1.33-1.98) or use of an online pharmacy (aOR, 2.30; 95% CI, 1.83-2.90) was associated with a greater likelihood of medication purchases outside the US. Individuals who skipped medications (aOR, 3.86; 95% CI, 3.05-4.88) or delayed filling a prescription (aOR, 4.04, 95% CI, 3.23-5.06) also had higher odds of purchasing medication outside the US. Conclusions and Relevance: The findings suggest that patients are not using prescription purchases outside the US to meet their medication needs. However, monitoring to promote safe administration of medications imported into the US should be continued.
Probing cosmic birefringence with polarized Sunyaev-Zel'dovich tomography
Creators: name: Lee, Nanoom
name: Hotinli, Selim C.
name: Kamionkowski, Marc
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: If the physics behind dark energy and/or dark matter violates the parity symmetry assumed in the standard cosmological paradigm, the linear polarization of the cosmic microwave background (CMB) photons can rotate due to their coupling to the dark sector. Recent 3$σ$ hints of this ``cosmic birefringence" in the EB spectrum of the CMB polarization motivates us to pursue new directions to independently validate and characterize the signal. Here, we explore the prospects to probe cosmic birefringence from small-scale fluctuations in the CMB using polarized Sunyaev-Zel'dovich (pSZ) tomography. We find that pSZ can be used to infer the redshift dependence of cosmic birefringence and also help calibrate the instrumental polarization orientation. To illustrate the prospects, we show that pSZ tomography may probe an axion-like dark energy model with masses $m_ϕ\lesssim 10^{-32}$eV with $\mathcal{O}(0.1)$ degrees of rotation between reionization and recombination.
description: 11+3 pages, 10 figures, version accepted for publication in PRD
Aturus scutelliferus Walter 1928
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Aturidae
Aturus
Aturus scutelliferus

description: Aturus scutelliferus Walter, 1928
Records from the study area: Punjab—Walter (1928); Prasad (1974).
Habitat: Mountain streams.
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 17, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
On quantum interferometric measurements of temperature
Creators: name: Jarzyna, Marcin
name: Zwierz, Marcin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We provide a detailed description of the quantum interferometric thermometer, which is a device that estimates the temperature of a sample from the measurements of the optical phase. For the first time, we rigorously analyze the operation of such a device by studying the interaction of the optical probe system prepared in a single-mode Gaussian state with a heated sample modeled as a dissipative thermal reservoir. We find that this approach to thermometry is capable of measuring the temperature of a sample in the nanokelvin regime. Furthermore, we compare the fundamental precision of quantum interferometric thermometers with the theoretical precision offered by the classical idealized pyrometers, which infer the temperature from a measurement of the total thermal radiation emitted by the sample. We find that the interferometric thermometer provides a superior performance in temperature sensing even when compared with this idealized pyrometer. We predict that interferometric thermometers will prove useful for ultraprecise temperature sensing and stabilization of quantum optical experiments based on the nonlinear crystals and atomic vapors.
description: 13 pages, 3 figures, final version
title: Zeugnisse jüdischen Lebens in Ellrich am Harz
Creators: name: Zahradnik, Marie-Luis
Publisher: name: Hochschule
Year: 2023
Subjects: subject: Juden
subject: Mikwe
subject: Synagoge
subject: Friedhof
subject: Beschneidungsbuch
subject: Ellrich
subject: 900
subject: 290
subject: 943
subject: 300

description: Eine Feuer- und Hasswelle ging im nationalsozialistischen Dritten Reich in der Nacht vom 9. auf den 10. November 1938 über die bis dahin lang etablierte jüdische Kultur, Religion und Gesellschaft hinweg. Rund 1.400 Synagogen und Betstuben wurden niedergebrannt, darunter auch die Fachwerksynagoge der jüdischen Gemeinde in Ellrich. Im Gedenken widmet sich der Aufsatz dem jüdischen Leben in Ellrich, mit dem Blick auf die verschwundenen Orte, insbesondere die Synagoge. Die neuzeitlich gegründete jüdische Gemeinde in Ellrich pflegte lange ein konservativ-orthodoxes Brauchtum, was an der Einrichtung des Gotteshauses und der Gestaltung des Friedhofes und der Grabsteine zum Ausdruck kam. Wie viele andere alte Landgemeinden auch, war die jüdische Gemeinde in Ellrich ab der zweiten Hälfte des 19. Jahrhunderts von einer anhaltenden Abnahme der Mitgliederzahl betroffen, verbunden mit krisenhaften Folgen für die religiöse Praxis. Aus archivalischen, literarischen und visuellen Quellen wird ein Bild über die Entwicklung der Gemeinde und über ihre religiösen Orte rekonstruiert.
Changes in Opioid Use After Florida's Restriction Law for Acute Pain Prescriptions
Creators: name: Goodin, A.
name: Usmani, S.A.
name: Hincapie-Castillo, J.M.
name: Possinger, M.-C.
name: Vouri, S.M.
Publisher: name: NLM (Medline)
Year: 2020

description: Several US states have enacted laws to limit either opioid prescription days’ supply or morphine milligram equivalents for the treatment of acute pain. On July 1, 2018, Florida implemented House Bill 21 (HB21), which limits the days’ supply of Schedule II opioids to 3 days for acute pain prescriptions. Prescribers can extend to a 7-day supply if they document an exception. This quality improvement study aims to assess the outcomes associated with Florida’s restriction law on opioid prescribing by evaluating the number of new opioid users and the number of units dispensed per prescription before and after the policy change.
Sensitivity of the GAPS Experiment to Low-energy Cosmic-ray Antiprotons
Creators: name: Rogers, Field
name: Aramaki, Tsuguo
name: Boezio, Mirko
name: Boggs, Steven
name: Bonvicini, Valter
name: Bridges, Gabriel
name: Campana, Donatella
name: Craig, William W.
name: von Doetinchem, Philip
name: Everson, Eric
name: Fabris, Lorenzo
name: Feldman, Sydney
name: Fuke, Hideyuki
name: Gahbauer, Florian
name: Gerrity, Cory
name: Hailey, Charles J.
name: Hayashi, Takeru
name: Kawachi, Akiko
name: Kozai, Masayoshi
name: Lenni, Alex
name: Lowell, Alexander
name: Manghisoni, Massimo
name: Marcelli, Nadir
name: Mochizuki, Brent
name: Mognet, Isaac
name: Munakata, Kazuoki
name: Munini, Riccardo
name: Nakagami, Yusuke
name: Olson, Jerome
name: Ong, Rene
name: Osteria, Guiseppe
name: Perez, Kerstin M.
name: Quinn, Sean
name: Re, Valerio
name: Riceputi, Elisa
name: Roach, Brandon
name: Ryan, Jaime
name: Saffold, Nathan
name: Scotti, Valentina
name: Shimizu, Yuki
name: Sparvoli, Roberta
name: Stoessl, Achim
name: Tiberio, Alessio
name: Vannuccini, Elena
name: Wada, Takuya
name: Xiao, Mengjiao
name: Yamatani, Masahiro
name: Yee, Kelsey
name: Yoshida, Atsumasa
name: Yoshida, Tetsuya
name: Zampa, Gianluigi
name: Zeng, Jiancheng
name: Zweerink, Jeffrey
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The General Antiparticle Spectrometer (GAPS) is an upcoming balloon mission to measure low-energy cosmic-ray antinuclei during at least three ~35-day Antarctic flights. With its large geometric acceptance and novel exotic atom-based particle identification, GAPS will detect ~500 cosmic antiprotons per flight and produce a precision cosmic antiproton spectrum in the kinetic energy range of ~0.07-0.21 GeV/n at the top of the atmosphere. With these high statistics extending to lower energies than any previous experiment, and with complementary sources of experimental uncertainty compared to traditional magnetic spectrometers, the GAPS antiproton measurement will be sensitive to dark matter, primordial black holes, and cosmic ray propagation. The antiproton measurement will also validate the GAPS antinucleus identification technique for the antideuteron and antihelium rare-event searches. This analysis demonstrates the GAPS sensitivity to cosmic-ray antiprotons using a full instrument simulation and event reconstruction, and including solar and atmospheric effects.
description: 11 pages, 9 figures, revision updated with addition of Figure 5 and slight changes in the text to match the version accepted by Astroparticle Physics
Sport and delinquency: an examination of the deterrence hypothesis in a longitudinal study.
Creators: name: Begg, Dorothy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: OBJECTIVE: To determine whether involvement in sporting activity in mid-adolescence would deter delinquent behaviour in late adolescence.

METHODS: Members of a longitudinal cohort study were interviewed at ages 15 and 18 years and, among other topics, were asked questions relating to involvement in physical activity and delinquent behaviour. Logistic regression models were used to examine the relation between sports involvement and delinquency at age 15 years and delinquency at age 18.

RESULTS: After controlling for delinquent behaviour and psychosocial factors at age 15, females with moderate or high levels of sporting activity, and males with high levels of sporting activity, were significantly more likely to be delinquent at age 18 years than those with low levels of sporting activity. No significant association was found between sporting activity and aggressive behaviour, team sport participation and delinquency, and team sport participation and aggressive behaviour.

CONCLUSIONS: This study did not support the deterrence hypothesis and showed that high involvement in sporting activity, but not team sport, was associated with a subsequent increase in delinquent behaviour.
The New Zealand rugby injury and performance project. IV. Anthropometric and physical performance comparisons between positional categories of senior A rugby players.
Creators: name: Waller, A. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: OBJECTIVE--To describe the anthropometric and physical performance characteristics of a sample of senior A club rugby players and to highlight differences between the positional categories of the players within the forwards and backs. METHODS--94 senior A male rugby players were assessed on a number of anthropometric and physical performance assessments. The forwards were categorised into props, hookers, locks, and loose forwards. Backs were categorised into inside, midfield, and outside backs. Categories within the forwards were compared with each other, as were the categories within the backs. RESULTS--The anthropometric characteristics of forwards differed significantly between positional categories. Front row forwards (props and hookers) possessed highly endo-mesomorphic somatotypes, and typically rated very low for ectomorphy. Props possessed greater body mass than hookers. Locks and loose forwards were taller than the front row forwards. In terms of physical performance fewer differences were observed. Hookers performed better than props on an aerobic assessment. Locks and loose forwards were faster than the front row forwards on a 30 m sprint from a running start. The inside backs were shorter and lighter than the midfield and outside backs. CONCLUSIONS--The combination of anthropometric characteristics and physical performance attributes observed allows players to best meet the demands imposed on them by their position.
Moving the collections of an academic health sciences library.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1982

description: Expansion of the physical facilities of the Health Sciences Library at the University of North Carolina at Chapel Hill necessitated relocating the entire journal and book collections within the library. This paper discusses the problems involved in planning such a move, the gathering and analysis of relevant data, the formulation of an overall plan based on the data analysis, and the actual move. The use of specially-written computer programs greatly aided in the move's planning and execution and also yielded quantitative data describing the characteristics of an academic health sciences collection.
Safety in coils: predation rates of ambush hunting rattlesnakes are extremely low
Creators: name: Maag, Dylan
name: Clark, Rulon
Publisher: name: Brill Online
Year: 2022
Subjects: Ecology not elsewhere classified

description: Rattlesnakes are widespread mesopredators that are themselves killed and eaten by a host of other predators, including birds of prey and carnivorous mammals. Although anecdotal accounts of rattlesnake depredation are common, there are few quantitative data on encounter rates between rattlesnakes and their predators. Here we review a large database of encounters between rattlesnakes and their predators recorded from field videography of snakes in the sit-and-wait phase of their ambush hunting strategy. We found that, across 8300 hours of observation, adult rattlesnakes of six species and multiple populations exhibit low encounter rates with predators; furthermore, when predators were encountered, we never observed them to attack or kill coiled snakes. Thus, we propose that rattlesnakes are preyed upon while performing other, riskier behaviors associated with moving through the landscape. We also discuss why rattlesnakes are at low risk of predation while hunting on the surface.
A checklist for planning and designing audiovisual facilities in health sciences libraries.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1984

description: Developed by an MLA/HeSCA (Health Sciences Communications Association) joint committee, this checklist is intended to serve as a conceptual framework for planning a new or renovated audiovisual facility in a health sciences library. Emphasis is placed on the philosophical and organizational decisions that must be made about an audiovisual facility before the technical or spatial decisions can be wisely made. Specific standards for facilities or equipment are not included. The first section focuses on health sciences library settings. Ideas presented in the remaining sections could apply to academic learning resource center environments as well. A bibliography relating to all aspects of audiovisual facilities planning and design is included with references to specific sections of the checklist.
The role of social structure in defining population dynamics of house mice in Australian cropping systems
Creators: name: Van de Weyer, Nikki
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The development of informed management strategies is necessary to mitigate the impacts of eruptive pest species in Australian agricultural systems. The ability to successfully maintain or reduce pest population density to below a damage threshold relies on identifying the critical regulators of population growth and stability. For many eruptive species, social structures are thought to strongly impact these key population parameters. Understanding how social structures translate to population-level dynamics is a key challenge, especially in small mammals. This study aims to investigate the underlying social mechanism(s) that might be influencing population dynamics. The study used a combination of spatially explicit capture-recapture models and single nucleotide polymorphisms (SNP) genotyping to test predictions of the self-regulation hypothesis proposed by Krebs et al., (1995) and Sutherland et al., (2005) using neighbouring house mouse (Mus musculus domesticus) populations that show distinctly different trajectories. Firstly, I test if space use in the spring (low population phase) differs between outbreaking and non-outbreaking populations. Secondly, I estimate pairwise kinship to test if female relatedness is higher during the spring in outbreaking populations and investigate changes in relatedness between different seasons. Females in outbreaking populations had lower home range overlap compared to non- outbreaking populations. Kinship was low between populations and seasons, however the non- outbreaking populations had a stable number of close relatives and resident mice over time. The study showed that female house mice have greater potential to form kin groups in more stable non-outbreaking populations during spring and early summer, thus, providing a foundation for future studies to investigate how these differences could help to improve management strategies.
Revisiting diagonal tetrads: New Black Hole solutions in $f(T)$ gravity
Creators: name: Awad, Adel
name: Golovnev, Alexey
name: Guzmán, María-José
name: Hanafy, Waleed El
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study various forms of diagonal tetrads that accommodate Black Hole solutions in $f(T)$ gravity with certain symmetries. As is well-known, vacuum spherically symmetric diagonal tetrads lead to rather boring cases of constant torsion scalars. We extend this statement to other possible horizon topologies, namely, spherical, hyperbolic and planar horizons. All such cases are forced to have constant torsion scalars to satisfy the anti-symmetric part of the field equations. We give a full classification of possible vacuum static solutions of this sort. Furthermore, we discuss addition of time-dependence in all the above cases. We also show that if all the components of a diagonal tetrad depend only on one coordinate, then the anti-symmetric part of the field equations is automatically satisfied. This result applies to the flat horizon case with Cartesian coordinates. For solutions with a planar symmetry (or a flat horizon), one can naturally use Cartesian coordinates on the horizon. In this case, we show that the presence of matter is required for existence of non-trivial solutions. This is a novel and very interesting feature of these constructions. We present two new exact solutions, the first is a magnetic Black Hole which is the magnetic dual of a known electrically charged Black Hole in literature. The second is a dyonic Black Hole with electric and magnetic charges. We present some features of these Black holes, namely, extremality conditions, mass, behavior of torsion and curvature scalars near the singularity.
description: pdfLaTeX, 21 pages, one figure. Submitted to EPJC
Templated Synthesis of Exfoliated Porous Carbon with Dominant Graphitic Nitrogen
Creators: name: Doustkhah, Esmail
name: Kotb, Ahmed
name: Tafazoli, Saeede
name: Balkan, Timuçin
name: Kaya, Sarp
name: Hanaor, Dorian A. H.
name: Assadi, M. Hussein N.
Publisher: name: Technische Universität Berlin
Year: 2023
Subjects: subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften
subject: hard template
subject: graphitic nitrogen
subject: carbon nitride
subject: supercapacitance
subject: 2D hard template
subject: Graphitic carbon nitride
subject: g-C3N4

description: We present here a new approach for the synthesis of nitrogen-doped porous graphitic carbon (g-NC) with a stoichiometry of C6.3H3.6N1.0O1.2, using layered silicate as a hard sacrificial template. Autogenous exfoliation is achieved due to the heterostacking of 2D silicate and nitrogen-doped carbon layers. Micro- and meso-porosity is induced by melamine and cetyltrimethylammonium (C16TMA). Our density functional calculations and X-ray photoelectron spectroscopy (XPS) observations confirm that the most dominant nitrogen configuration in g-CN is graphitic, while pyridinic and pyrrolic nitrogens are thermodynamically less favored. Our large-scale lattice dynamics calculations show that surface termination with H and OH groups at pores accounts for the observed H and O in the composition of the synthesized g-NC. We further evaluate the electrocatalytic and the supercapacitance activities of g-NC. Interestingly, this material exhibits a specific capacitance of ca. 202 F g–1 at 1 A g–1, retaining 90% of its initial capacitance after 10,000 cycles.
Control and mitigation of microwave crosstalk effect with superconducting qubits
Creators: name: Wang, Ruixia
name: Zhao, Peng
name: Jin, Yirong
name: Yu, Haifeng
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Improving gate performance is vital for scalable quantum computing. The universal quantum computing also requires the gate fidelity to reach a high level. For superconducting quantum processor, which operates in the microwave band, the single-qubit gates are usually realized with microwave driving. The crosstalk between microwave pulses is a non-negligible error source. In this article, we propose an error mitigation scheme to address this crosstalk issue for single-qubit gates. There are three steps in our method. First, by controlling the detuning between qubits, the microwave induced classical crosstalk error can be constrained within the computational subspace. Second, by applying the general decomposition procedure, arbitrary single-qubit gate can be decomposed as a sequence of $\sqrt{X}$ and virtual Z gates. Finally, by optimizing the parameters in virtual Z gates, the error constrained in the computational space can be corrected. Using our method, no additional compensation signals are needed, arbitrary single-qubit gate time will not be prolonged, and the circuit depth containing simultaneous single-qubit gates will also not increase. The simulation results show that, in specific regime of qubit-qubit detuning, the infidelities of simultaneous single-qubit gates can be as low as which without microwave crosstalk.
“Cookbook medicine”: Exploring the impact of opioid prescribing limits legislation on clinical practice and patient experiences
Creators: name: Chelminski, P.R.
name: Carey, T.S.
name: Blackburn, N.A.
name: Dorris, S.W.
name: Ranapurwala, S.I.
name: Dasgupta, N.
name: Nocera, M.
name: Joniak-Grant, E.
Publisher: name: Elsevier Ltd
Year: 2023

description: Opioid dependence and overdose are serious public health concerns. States have responded by enacting legislation regulating opioid-prescribing practices. Through in-depth interviews with clinicians, state officials, and organizational stakeholders, this paper examines opioid prescribing limits legislation (PLL) in North Carolina and how it impacts clinical practice. Since the advent of PLL, clinicians report being more mindful when prescribing opioids and as expected, writing for shorter durations for both acute and postoperative pain. But clinicians also report prescribing opioids less frequently for acute pain, refusing to write second opioid prescriptions, foisting responsibility for patient pain care onto other clinicians, and no longer writing opioid prescriptions for chronic pain patients. They directly credit PLL for these changes, including institutional policies enacted in response to PLL, and, to a lesser degree, notions of “do no harm.” However, we argue that misapplication of and ambiguities in PLL along with defensive medicine practices whereby clinicians and their institutions center their legal interests over patient care, amplify these restrictive changes in clinical practice. Clinicians’ narratives reveal downstream consequences for patients including undertreated pain, being viewed as drug-seeking when questioning opioid-prescribing decisions, and having to overuse the medical system to achieve pain relief.
Hurricane Florence and suicide mortality in North Carolina: A controlled interrupted time-series analysis
Creators: name: Fitch, K.V.
name: Cooper, T.
name: Carey, T.S.
name: Dorris, S.
name: Goldston, D.
name: Kavee, A.L.
name: Keil, A.P.
name: Ranapurwala, S.
name: Swilley-Martinez, M.
name: Pence, B.W.
name: Miller, V.E.
name: Gaynes, B.N.
Publisher: name: BMJ Publishing Group
Year: 2023

description: Background Natural disasters are associated with increased mental health disorders and suicidal ideation; however, associations with suicide deaths are not well understood. We explored how Hurricane Florence, which made landfall in September 2018, may have impacted suicide deaths in North Carolina (NC). Methods We used publicly available NC death records data to estimate associations between Hurricane Florence and monthly suicide death rates using a controlled, interrupted time series analysis. Hurricane exposure was determined by using county-level support designations from the Federal Emergency Management Agency. We examined effect modification by sex, age group, and race/ethnicity. Results 8363 suicide deaths occurred between January 2014 and December 2019. The overall suicide death rate in NC between 2014 and 2019 was 15.53 per 100 000 person-years (95% CI 15.20 to 15.87). Post-Hurricane, there was a small, immediate increase in the suicide death rate among exposed counties (0.89/100 000 PY; 95% CI -2.69 to 4.48). Comparing exposed and unexposed counties, there was no sustained post-Hurricane Florence change in suicide death rate trends (0.02/100 000 PY per month; 95% CI -0.33 to 0.38). Relative to 2018, NC experienced a statewide decline in suicides in 2019. An immediate increase in suicide deaths in Hurricane-affected counties versus Hurricane-unaffected counties was observed among women, people under age 65 and non-Hispanic black individuals, but there was no sustained change in the months after Hurricane Florence. Conclusions Although results did not indicate a strong post-Hurricane Florence impact on suicide rates, subgroup analysis suggests differential impacts of Hurricane Florence on several groups, warranting future follow-up.
THE MAIN CONTRIBUTION OF ALEXANDER FEINBERG 'S WORK TO UZBEK LITERATURE
Creators: name: Gulomova, Shakhzoda
Publisher: name: Zenodo
Year: 2023

description: This article discusses one of the outgoing writer Alexander Feinberg's work and his masterpiece in literature. The author of the article analyzed his work and gave his idea about Alexander Feinberg's  very works.
Rigorous convergence condition for quantum annealing
Creators: name: Kimura, Yusuke
name: Nishimori, Hidetoshi
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We derive a generic bound on the rate of decrease of transverse field for quantum annealing to converge to the ground state of a generic Ising model when quantum annealing is formulated as an infinite-time process. Our theorem is based on a rigorous upper bound on the excitation probability in the infinite-time limit and is a mathematically rigorous counterpart of a previously known result derived only from the leading-order term of the asymptotic expansion of adiabatic condition. Since our theorem gives a sufficient condition of convergence for a generic transverse-field Ising model, any specific problem may allow a better, faster, control of the coefficient.
description: 11 pages