cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Suppression of Ca2+ oscillations in cultured rat hepatocytes by chemical hypoxia.
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: The model of "chemical hypoxia" with KCN plus iodoacetic acid mimics the ATP depletion and reductive stress of hypoxia. Here, we examined the effects of chemical hypoxia on cytosolic free Na+ and Ca2+ in single cultured rat hepatocytes by multiparameter digitized video microscopy and ratio imaging of sodium-binding furan indicator (SBFI) and Fura-2. Intracellular Na+ increased from about 10 mM to more than 100 mM after 20 min of chemical hypoxia, whereas cytosolic free Ca2+ remained virtually unchanged. In normoxic hepatocytes, phenylephrine (50 microM) and Arg-vasopressin (20-40 nM) induced Ca2+ oscillations in 70 and 40% of cells, respectively. These Ca2+ oscillations were suppressed after one spike following the onset of chemical hypoxia. Phenylephrine and vasopressin also increased inositol phosphate formation by 22 and 147%, respectively. This effect was suppressed by KCN plus iodoacetate. Intracellular acidosis is characteristic of chemical hypoxia. Intracellular acidosis induced by 40 mM Na-acetate suppressed Ca2+ oscillations but did not inhibit hormone-induced inositol phosphate formation. Cytosolic alkalinization also suppressed Ca2+ oscillations. However, prevention of intracellular acidosis with monensin (10 microM) did not prevent suppression of Ca2+ oscillations during chemical hypoxia. Mitochondrial depolarization with uncoupler did not change free Ca2+ levels during chemical hypoxia, indicating that mitochondria do not regulate free Ca2+ during chemical hypoxia. From these results, we conclude: 1) chemical hypoxia does not block Na+ influx across the plasma membrane; 2) Chemical hypoxia inhibits hormone-stimulated Ca2+ flux pathways across cellular membranes by two different mechanisms: (a) by ATP depletion, which disrupts hormone-myo-inositol 1,4,5-triphosphate coupling, and (b) by intracellular acidosis, which inhibits myo-inositol 1,4,5-triphosphate-stimulated Ca2+ release from intracellular stores; 3) during ATP depletion by chemical hypoxia, mitochondria do not take up Ca2+ to maintain cytosolic free Ca2+ at low concentrations.
The multi-measure cosmological model and its peculiar effective potential
Creators: name: Staicova, Denitsa
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences
subject: 83Fxx

description: The multi-measures model applied to cosmology has been recently shown to reproduce qualitatively the expected stages of the Universe evolution, along with some unexpected features. In this article, we continue its exploration with a detailed study of the effective potential of the model. An analysis of the limits of applicability of the effective potential show that during most of the Universe evolution, the effective potential is a very good approximation of the actual potential term. There is, however, a deviation between the two occurring in the earliest moments of the evolution, which has an important role on the behavior of the inflaton scalar field. In the studied cases, during this initial time, the inflaton is increasing in absolute value, which seems consistent with "climbing up" the effective potential. To investigate this behavior, we use numerical integration to find the numerical potential and we show that during the early stage of the evolution, the shape of the numerical potential is very different from that of the effective one and instead of a left plateau followed by steep slope, one observes only a slope with additional local maximum and minimum. This result demonstrates that for complicated equations of motion of the inflaton, one should not rely only on the notion of kinetic and effective potential terms to describe the problem as they may not be accurate in the entire numerical domain.
description: 9 pages, 5 figures
The role of the epidermal growth factor-1 and hydrophobic stack domains of human factor IX in binding to endothelial cells
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: To determine the function and specificity in factor IX of the first epidermal growth factor (EGF)-like domain and the eight-amino acid hydrophobic stack encoded by exon C (residues 39-46), these domains were replaced by the corresponding polypeptide regions of factor X and chimeric proteins were produced in human embryo kidney cells. Both chimeras were activated by factor XIa at a rate similar to plasma factor IX and exhibited calcium-dependent fluorescence quenching similar to plasma factor IX. Both chimeras competed equally for binding to the endothelial cell receptor. Our findings make it unlikely that the first EGF-like domain or the hydrophobic stack of factor IX are responsible for the specific binding of factor IX to its endothelial cell receptor.
Local BRST cohomology in gauge theories
Creators: name: Barnich, Glenn
name: Brandt, Friedemann
name: Henneaux, Marc
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The general solution of the anomaly consistency condition (Wess-Zumino equation) has been found recently for Yang-Mills gauge theory. The general form of the counterterms arising in the renormalization of gauge invariant operators (Kluberg-Stern and Zuber conjecture) and in gauge theories of the Yang-Mills type with non power counting renormalizable couplings has also been worked out in any number of spacetime dimensions. This Physics Report is devoted to reviewing in a self-contained manner these results and their proofs. This involves computing cohomology groups of the differential introduced by Becchi, Rouet, Stora and Tyutin, with the sources of the BRST variations of the fields ("antifields") included in the problem. Applications of this computation to other physical questions (classical deformations of the action, conservation laws) are also considered. The general algebraic techniques developed in the Report can be applied to other gauge theories, for which relevant references are given.
description: 150 pages Latex file, minimal corrections, final version
Thyrotropin and insulin-like growth factor I regulation of tyrosine phosphorylation in FRTL-5 cells : interaction between cAMP-dependent and growth factor-dependent signal transduction
Creators: name: CONTI, M
name: EARP, H.
name: TAKAHASHI, S.
name: PROKOP, C
name: VAN WYK, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: Pretreatment of rat FRTL-5 thyroid cells with thyrotropin (TSH) markedly potentiated the mitogenic response to insulin-like growth factor I (IGF-I) (Tramontano, D., Moses, A. C., Veneziani, B. M., and Ingbar, S. H. (1988) Endocrinology 122, 127-132; Takahashi, S.-I., Conti, M., and Van Wyk, J. J. (1990) Endocrinology 126, 736-745). The present study was undertaken to determine whether this synergism between TSH and IGF-I in FRTL-5 cells was correlated with changes in tyrosine phosphorylation of intracellular proteins. Tyrosine phosphorylation in intact cells was determined by gel electrophoresis and immunoblotting using monospecific anti-phosphotyrosine antibodies. Cells were preincubated for up to 24 h with TSH, dibutyryl cAMP, forskolin, or cholera toxin and then incubated for an additional 1 min in the absence or presence of IGF-I. As reported by others, IGF-I rapidly increased tyrosine phosphorylation of a 175-kDa protein as well as a less intense band of 90-100 kDa. Pretreatment for 6-12 h with either TSH or other agents that elevate intracellular cAMP potentiated the IGF-I-dependent tyrosine phosphorylation of the 175-kDa substrate by 3-5-fold. Since TSH did not increase IGF receptor number of kinase activity, the effect of TSH is assumed to be exerted at a step distal to IGF receptor tyrosine kinase. Surprisingly, IGF-I-independent tyrosine phosphorylation was also increased by pretreatment with TSH. When intact cells were analyzed TSH produced a time- and concentration-dependent increase in tyrosine phosphorylation of a prominent 120-125-kDa substrate and less prominent 100- and 80-kDa substrates. Assays using Triton X-100-soluble extracts incubated with MgCl2, ATP, and orthovanadate demonstrated that TSH pretreatment increased tyrosine phosphorylation over that observed in untreated cells. In this cell-free assay, TSH pretreatment enhanced the phosphorylation of multiple substrates. These studies suggest that a cAMP stimulus that initiates a trophic effect can be propagated indirectly through multiple pathways including enhancement of tyrosine phosphorylation.
Pion Excess, Nuclear Correlations, and the Interpretation of ($\vec p, \vec n$) Spin Transfer Experiments
Creators: name: Koltun, Daniel S.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Conventional theories of nuclear interactions predict a net increase in the distribution of virtual pions in nuclei relative to free nucleons. Analysis of data from several nuclear experiments has led to claims of evidence against such a pion excess. These conclusions are usually based on a collective theory (RPA) of the pions, which may be inadequate. The issue is the energy dependence of the nuclear response, which differs for theories with strong NN correlations from the RPA predictions. In the present paper, information about the energy dependence is extracted from sum rules, which are calculated for such a correlated, noncollective nuclear theory. The results lead to much reduced sensitivity of nuclear reactions to the correlations that are responsible for the pion excess. The primary example is $(\vec p,\vec n)$ spin transfer, for which the expected effects are found to be smaller than the experimental uncertainties. The analysis has consequences for Deep Inelastic Scattering (DIS) experiments as well.
description: 16 pages, LaTeX, no figures, submitted to Phys. Rev. C
Pheidole transversostriata
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole transversostriata

description: Pheidole transversostriata Mayr
Pheidole transversostriata Mayr 1887: 584. Syn.: Pheidole transversostriata var. nigridens Forel 1901 j: 362, n. syn.; Pheidole lacerta Wheeler 1922e: 6, n. syn. Possible synonym: Pheidole scalaris new species, this monograph. Raised to species level in this monograph and placed in the tachigaliae group: gibbata.
Types Naturhist. Mus. Wien.
Etymology L transversostriata, transversely lined, referring to the transverse carinulae of the major head.
Diagnosis A member of the transversostriata group distinguished in the major by the broad ladder-like array of transverse carinae that extend unbroken from the occiput to the frontal lobes where they curve anteriorly to the ends of the lobes. It is close to scalaris of Costa Rica, differing in the major in the lack of rugoreticulum on the occiput (completely reticulate in scalaris) and less elongate head (Head Length 1.2X Head Width versus Head Length 1.3X Head Width in scalaris), and in the minor by the completely foveolate sides of the pronotum (versus smooth and shiny in scalaris). However, a major syntype of transversostriata " var. nigridens " from Colombia has the corners of the occiput rugoreticulate and is thus intermediate between transversostriata and scalaris in this character. The two forms may prove to be geographic variants (or good species) when more material becomes available. Measurements (mm) Unique holotype major: HW 0.66, HL 0.80, SL 0.34, EL 0.10, PW 0.36. Minor (St. Thomas, Virgin Islands): HW 0.40, HL 0.44, SL 0.36, EL 0.06, PW 0.26.
color Major: medium yellowish brown, with head a shade lighter and gaster a shade darker than mesosoma and waist. Minor: concolorous yellowish brown, legs clear yellow.
range P. transversostriata is evidently a wide-ranging but locally uncommon species, known from scattered records from St. Thomas, Virgin Islands, and Trinidad (Port of Spain) to the Guianas, Colombia, and Rio de Janeiro and Santa Catarina, Brazil.
biology Forel (1901J) collected the species from soil in Colombia.
figure Upper: major (syntype of synonymous P. lacerta Wheeler, Port of Spain, Trinidad, compared with unique holotype of P. transversostriata). Lower: minor (Inner Brass, St. Thomas, Virgin Islands, associated with major compared with transversostriata holotype). (Type locality: Guianas.) Scale bars = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 645
Pheidole acamata Wilson, 2003, new species
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole acamata

description: Pheidole acamata new species
types Mus. Comp. Zool. Harvard.
Etymology Gr acamata, untiring, ceaseless.
diagnosis A member of the fallax group, similar to the species listed in the heading above, distinguished by the following combination of traits.
Major: small; yellow; dorsum of first gastral tergite covered by uniform layer of short, subappressed hairs; scape short of the occipital corner by twice its maximum width; a thin corridor of rugoreticulum extending from the eye to the circular carinulae of the antennal fossa; anterior dorsum of the pronotum rugoreticulate, with the rear of the pronotal dorsum bearing broken rugulae and the rest of the promesonotal dorsum shiny or subopaque.
Minor: all of the head, mesosoma, and waist foveolate and opaque; anterior half of the median strip of the first gastral tergite shagreened and opaque; occiput considerably narrowed but lacking a nuchal collar.
Measurements (mm) Holotype major: HW 0.98, HL 1.04, SL 0.76, EL 0.18, PW 0.52.
Paratype minor: HW 0.54, HL 0.60, SL 0.72, EL 0.12, PW 0.38.
Color Major: concolorous reddish yellow.
Minor: concolorous dark yellow.
Range Known only from the type series.
Biology Unknown.
Figure Upper: holotype, major. Lower: paratype, minor. NICARAGUA: Kukra River (Ivette Perfecto). Scale bars = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 258
Static properties of a quasi one-dimensional antiferromagnet in magnetic field
Creators: name: Zhitomirsky, M. E.
name: Zaliznyak, I. A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We calculate the effect of zero-point fluctuations on the magnetostatic properties of a quasi one-dimensional antiferromagnetic helimagnet with and without in-plane anisotropy. We find substantial reduction of the uniform susceptibility and the sublattice magnetization from their classical values and appreciable renormalization of the spin-flop field at $T=0$. The magnetization curve varies nonlinearly at small fields and is described by a universal formula at high fields. The results are compared with numerical simulations on one-dimensional systems and measurements in the CsNiCl$_3$-type compounds.
description: 18 pages, RevTEX, 3 figures available upon request, accepted to Phys. Rev. B
W Production in an Improved Parton-Shower Approach
Creators: name: Miu, Gabriela
name: Sjostrand, Torbjorn
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the description of the production properties of gauge bosons (W+/W-, Z0, gamma) at colliders, the lowest-order graph normally is not sufficient. The contributions of higher orders can be introduced either by an explicit order-by-order matrix-element calculation, by a resummation procedure or by a parton-shower algorithm. Each approach has its advantages and disadvantages. We here introduce a method that allows the parton-shower algorithm to be augmented by higher-order information, thereby offering an economical route to a description of all event properties. It is tested by comparing with the pT spectrum of W bosons at the Tevatron.
description: 1+9 pages, 5 eps-figures, submitted to Phys. Lett. B
Transcriptional activation and nuclear targeting signals of the human androgen receptor
Creators: name: SIMENTAL, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: The androgen receptor (AR) is a signal-transducing protein required for sexual differentiation, development, and expression of the male phenotype. A series of human AR deletion mutants were created either by site-directed mutagenesis using restriction enzyme digestion, the polymerase chain reaction, or, for a series of unidirectional NH2-terminal deletions, exonuclease III digestion. Receptor mutants were expressed in monkey kidney COS cells as truncated AR proteins between 20 and 107 kDa as revealed on immunoblots, where wild type AR was a doublet of 114 and 108 kDa. Subcellular localization by immunocytochemical staining demonstrated androgen-dependent nuclear uptake of AR from a perinuclear region of the cytoplasm. A nuclear targeting signal similar in sequence and position to the glucocorticoid receptor and homologous to the SV40 large T antigen was required for androgen-induced nuclear uptake of wild type AR. AR mutants lacking the NH2-terminal and/or steroid binding domains were constitutively nuclear with reduced transcriptional activity. Transcriptional activation by wild type AR was androgen-dependent in cotransfection studies of CV1 cells using the chloramphenicol acetyltransferase reporter gene linked to the mouse mammary tumor virus promoter. Deletion mutagenesis revealed within the NH2-terminal region a domain required for full transcriptional activity and within the steroid binding domain, an inhibitory function, deletion of which yielded a constitutively active receptor. Inhibition of wild type AR by coexpression with an inactive NH2-terminal fragment suggested competition for nuclear factors required for transcriptional regulation. These studies demonstrate a concerted interplay among the domains of the AR protein in regulating gene transcription.
Pheidole aculifera Wilson, 2003, new species
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole aculifera

description: Pheidole aculifera new species
Types Mus. Comp. Zool. Harvard.
Etymology L aculifera, needle-bearing, referring to the long, very thin propodeal spine of the major and minor.
Diagnosis A small, yellow member of the fallax group (but close to the diligens group) distinguished by the exceptionally thin propodeal spines of the major and minor, as well as the very low mesonotal convexity in side view in both castes; and, in the major, the exceptionally large spiracle.
Similar to prostrata of Costa Rica, but easily distinguished in the major by the large spiracle, low mesonotal convexity, and presence of a rugoreticulum mesad to the eyes, as well as yellow coloration. See also the less similar boruca, variegata, and violacea.
Measurements (mm) Holotype major: HW 0.96, HL 1.00, SL 0.78, EL 0.14, PW 0.42.
Paratype minor: HW 0.44, HL 0.54, SL 0.72, EL 0.10, PW 0.28.
Color Major: body light reddish yellow, appendages yellow.
Minor: concolorous yellow. 1
Range Known only from the type series.
Biology Unknown.
Figure Upper: holotype, major. Lower: paratype, minor. PANAMA: Nusagandi, San Bias (Leeanne E. Tennant-Alonso). Scale bars = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 259
An application of the 3-dimensional q-deformed harmonic oscillator to the nuclear shell model
Creators: name: Raychev, P.
name: Roussev, R.
name: Iudice, N. Lo
name: Terziev, P.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: An analysis of the construction of a q-deformed version of the 3-dimensional harmonic oscillator, which is based on the application of q-deformed algebras, is presented. The results together with their applicability to the shell model are compared with the predictions of the modified harmonic oscillator.
description: 12 pages, LaTeX
title: Transcriptions du Registre des écrous du Châtelet de Paris, Y5266 , page #1000844
Creators: name: Brochard, Pierre
name: Claustre, Julie
name: Regazzi, Hugo
name: Claustre, Julie
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Châtelet de Paris
subject: http://www.idref.fr/032506511/id

description: Transcriptions de certaines pages du Registre des écrous du Châtelet de Paris, Y5266
Les images liées sont indiquées par le champ Source.

Les transcriptions sont dans deux formats : Txt et PageXml.
description: Source: http://nakala.fr/11280/b36c936f
description: Source: http://www.nakala.fr/data/11280/b36c936f
description: Relation: https://lamop.hypotheses.org/
description: Bibliographic citation: Hugo Regazzi, Pierre Brochard, Julie Claustre - Transcriptions du Registre des écrous du Châtelet de Paris, Y5266 , page #1000844
description: Transcriptions du Registre des écrous du Châtelet de Paris, Y5266, page #1000844 - Format Text
description: Transcriptions du Registre des écrous du Châtelet de Paris, Y5266, page #1000844 - Format PageXml
A cardiac troponin T epitope conserved across phyla
Creators: name: Malouf, NN
name: McMahon, D
name: Anderson, PA
name: Oakeley, AE
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: Troponin T is a thin filament protein that is important in regulating striated muscle contraction. We have raised a monoclonal antibody against rabbit cardiac troponin T, monoclonal (mAb) 13-11, that recognizes its epitope in cardiac troponin T isoforms from fish, bird, and mammal but not from frog. The number of these isoforms expressed in cardiac muscle varies among species and during development. Cardiac troponin T isoforms were not found in adult skeletal muscle, while they were expressed transiently in immature skeletal muscle. We have mapped the epitope recognized by mAb 13-11 using rabbit cardiac troponin T isoforms. Analysis of stepwise cyanogen bromide digestion, which allowed association of the epitope to regions spanning methionine residues, coupled with immunoactivity of synthetic peptides, corresponding to sequences containing methionine residues, indicated that mAb 13-11 recognized its epitope in a 17-residue sequence containing the methionine at position 68, SKPKPRPFMPNLVPPKI. Comparison of skeletal and cardiac troponin T sequences suggested that the epitope was contained within the sequence FMPNLVPPKI. Synthetic peptides PFMPNLVPPKI and FMPNLVPPKI were recognized by mAb 13-11 on slot-blots. Enzyme-linked immunosorbent assay demonstrated mAb 13-11 recognized, in order of descending affinity, the 17-, 11-, and 10-residue sequence. Preabsorption of mAb 13-11 with each of these sequences blocked the recognition of the 17-residue peptide by mAb 13-11. The domain, PFMPNLVPPKI is encoded by the 5' region of the cardiac gene exon 10 and is present in hearts across a broad range of phyla. These findings suggest that this cardiac troponin T-specific sequence confers onto myofilaments structural and functional properties unique to the heart.
The edge of space: Revisiting the Karman Line
Creators: name: McDowell, Jonathan C.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: In this paper I revisit proposed definitions of the boundary between the Earth's atmosphere and outer space, considering orbital and suborbital trajectories used by space vehicles. In particular, I investigate the inner edge of outer space from historical, physical and technological viewpoints and propose 80 kilometers as a more appropriate boundary than the currently popular 100 km Von Kármán line.
description: 17 pages, 4 figures
A comparison of three heparin-binding serine proteinase inhibitors
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: The purpose of this study was to compare three heparin-binding plasma proteinase inhibitors in order to identify common and unique features of heparin binding and heparin-enhanced proteinase inhibition. Experiments with antithrombin, heparin cofactor, and protein C inhibitor were performed under identical conditions in order to facilitate comparisons. Synthetic peptides corresponding to the putative heparin binding regions of antithrombin, heparin cofactor, and protein C inhibitor bound to heparin directly and interfered in heparin-enhanced proteinase inhibition assays. All three inhibitors obeyed a ternary complex mechanism for heparin-enhanced thrombin inhibition, and the optimum heparin concentration was related to the apparent heparin affinity of the inhibitor. The maximum inhibition rate and rate enhancement due to heparin appeared to be unique properties of each inhibitor. In assays with heparin oligosaccharides of known size, only the antithrombin-thrombin reaction exhibited a sharp threshold for rate enhancement at 14-16 saccharide units. Acceleration of antithrombin inhibition of factor Xa, heparin cofactor inhibition of thrombin, and protein C inhibitor inhibition of thrombin, activated protein C, and factor Xa did not require a minimum saccharide size. The differences in heparin size dependence and rate enhancement of proteinase inhibition by these inhibitors might reflect differences in the importance of the ternary complex mechanism and other mechanisms, alterations in inhibitor reactivity, and orientation effects in heparin-enhanced proteinase inhibition.
Pheidole acutidens
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole acutidens

description: Pheidole acutidens (Santschi)
Bruchomyrma acutidens Santschi 1922e: 249. Combination with Pheidole by Wilson 1984b: 327. Types Naturhist. Mus. Basel.
etymology L acutidens, sharp-pointed tooth apparently referring to the reduced, acute mandible.
diagnosis An extreme workerless social parasite of Pheidole nitidula, with adaptations that make it unique within the genus. Queen: with 9- to 11-segmented antennae and minute, falcate toothless mandibles that taper to needle-sharp points. Male: pupiform, with mandibles vestigial or absent.
measurements (mm) Syntype queen: HW 0.40, HL 0.42, SL 0.72, EL 0.12, PW 0.58.
Color Queen: yellowish brown.
Range Known only from the type locality.
Biology P. acutidens is a permanent workerless parasite of Pheidole nitidula. The discoverer of this remarkable species, Carlos Bruch (1931), has provided extensive notes on its anatomy, ecology, behavior, and life cycle.
Figure Queen. ARGENTINA: La Plata, Buenos Aires (Carlos Bruch). Type locality: Alta Gracia (La Granja). Sierra de Cordoba, Argentina. Scale bar = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 260
A metal ion-binding site in the kringle region of bovine prothrombin fragment 1.
Creators: name: BERKOWITZ, P
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: 45Ca(II) binding studies (equilibrium dialysis) on the kringle domain of bovine prothrombin fragment 1 were conducted using a mixture of peptides (residues 43-156 and 46-156) resulting from limited alpha-chymotryptic hydrolysis of fragment 1. Analysis of the Scatchard plot of these data indicates a single, low affinity Ca(II)-binding site to be present. Similar results were obtained from studies on the decarboxylated fragment 1 derivative, 10-gamma-MGlu-fragment 1. Acetylation of bovine fragment 1 in the absence of Ca(II) or Mg(II) ions results in the loss of the metal ion-promoted quenching of the intrinsic Trp fluorescence of the protein and the Ca(II)-mediated binding to phosphatidylserine/phosphatidylcholine (PS/PC) vesicles. The acetylation of the NH2 alpha-group of Ala-1 has been shown (Welsch, D. J., and Nelsestuen, G. L. (1988) Biochemistry 27, 4946-4952) to abolish the PS/PC binding property of fragment 1. The present study demonstrates that acetylation of a second site possibly Ser-79 or Thr-81 using the conditions described in the preceding paper results in loss of both the fluorescence transition and the Ca(II)-mediated PS/PC binding of the resulting protein derivative. Removal of the O-acetyl group at the Ser-79/Thr-81 site is accomplished by aminolysis with 0.2 M hydroxylamine, pH 10, 50 degrees C; the fluorescence transition is partially restored. PS/PC binding is partially restored if the NH2 alpha-group of Ala-1 is trinitrophenylated but is not restored if the NH2 alpha-group of Ala-1 is acetylated. We conclude that the Ser-79/Thr-81 site may represent a portion of the metal ion-binding site within the kringle domain of fragment 1. Occupancy of this site by a Ca(II) ion appears to be important in the binding of the protein to PS/PC vesicles.
A_Study_on_Intellectual_Property_Management_and_Security_With_the_Law_of_Democratic_People_s_Republic_of_Korea.pdf
Creators: name: Shin, Hongseop
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 480603
subject: Intellectual property law
classificationCode: 460805
subject: Fairness, accountability, transparency, trust and ethics of computer systems

description: Addressing the qualitative competitiveness gap in intellectual property (IP) requires companies to strategically manage their IP assets. This involves generating and leveraging internationally competitive IP to maximize economic value. Key aspects include fostering specialized IP personnel through systematic training, strengthening the expertise of dedicated IP departments, and prioritizing information security to prevent valuable IP leaks. Additionally, companies should focus on effectively managing trade secrets and investing in robust information protection measures. In the context of North Korea, navigating the complexities of its IP legal framework, which is characterized by frequent changes and a lack of transparency, poses a significant challenge. Companies must also contend with a time-consuming and often opaque administrative system for IP rights acquisition and enforcement. Therefore, a successful IP strategy in North Korea necessitates a deep understanding of its unique legal landscape, proactive measures to safeguard against infringement, and a long-term perspective that accounts for potential systemic changes. Ultimately, a proactive approach to IP, including strategic patent filings and utilization, is crucial for driving industrial development and maintaining a competitive edge in any market, particularly one as complex as North Korea.
Rare Radiative B -> τ^+ τ^- γdecay in the two Higgs doublet Model
Creators: name: Iltan, E. O.
name: Turan, G.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The radiative B ->τ^+ τ^- γdecay is investigated in the framework of the two Higgs doublet model . The dependence of the differential branching ratio on the photon energy and the branching ratio on the two Higgs doublet model parameters, m_{H^\pm} and \tan β, are studied. It is shown that there is an enhancement in the predictions of the two Higgs doublet model compared to the Standard model case. We also observe that contributions of neutral Higgs bosons to the decay are sizable when \tanβis large.
description: 16 pages, 4 figures
A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs : molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: Multiple isozymes of cyclic nucleotide phosphodiesterases (PDEs) are expressed simultaneously in mammalian tissues. To identify and clone these PDEs, a polymerase chain reaction (PCR) strategy was developed using degenerate oligonucleotide primers designed to hybridize with highly conserved PDE DNA domains. Both known and novel PDEs were cloned from rat liver, the mouse K30a-3.3 lymphoma cell line, and a human hypothalamus cDNA library, demonstrating that these PCR primers can be used to amplify the cDNA of multiple PDE isozymes. One unique mouse PDE clone was found to encode a polypeptide identical with the corresponding portion of the bovine brain 63-kDa calmodulin-dependent PDE as reported in the companion article (Bentley, J. K., Kadlecek, A., Sherbert, C. H., Seger, D., Sonnenburg, W. K., Charbonneau, H., Novack, J. P., and Beavo, J. A. (1992) J. Biol. Chem. 267, 18676-18682). This mouse clone was used as a probe to screen a rat brain cDNA library for a full-length clone. The conceptual translation of the nucleotide sequence of the resulting rat clone has an open reading frame of 535 amino acids and maintains a high degree of homology with the bovine 63-kDa calmodulin-dependent PDE, indicating that this protein is likely to be the rat homolog of the 63-kDa calmodulin-dependent PDE. Expression of the full-length clone in Escherichia coli yielded a cGMP hydrolyzing activity that was stimulated severalfold by calmodulin. Northern blot analysis demonstrated that the mRNA encoding this PDE is highly expressed in rat brain and also in the S49.1 T-lymphocyte cell line. These data demonstrate that the PCR method described is a viable strategy to isolate cDNA clones of known and novel members of different families of PDE isozymes. Molecular cloning of these PDEs will provide valuable tools for investigating the roles of these isozymes in regulation of intracellular concentrations of the cyclic nucleotides.
title: ADCO, Comptes du Petit-Cîteaux (1477-1491) (11 H 1179), f. 00001
Creators: name: de la Côte d'Or, Archives départementales
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Archives Départementales De La Côte D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179), f. 00001, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
title: 01_0199
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Pheidole aenescens Wilson, 2003, new species
Creators: name: Wilson, E. O.
Publisher: name: Harvard University Press
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Pheidole
Pheidole aenescens

description: Pheidole aenescens new species
Types Mus. Comp. Zool. Harvard.
etymology L aenescens, bronze-like, referring to the body color.
diagnosis A medium-sized light reddish brown ("coppery") member of the fallax group similar to the species listed in the heading above, distinguished by the following combination of traits.
Major: head heart-shaped with extensive, wide-celled rugoreticulum ranging from mesad to the eyes and laterad from the frontal lobes posteriorly to the occiput along the midline, but with the occipital lobes remaining smooth and shiny; pilosity long and very dense over the entire dorsal surface of the body. Minor: occiput narrowed, with narrow nuchal collar.
In both major and minor the scapes are covered with long, erect and suberect hairs, not illustrated. measurements (mm) Holotype major: HW 1.06, HL 1.14, SL 0.94, EL 0.20, PW 0.54. Paratype minor: HW 0.54, HL 0.70, SL 0.90, EL 0.16, PW 0.40.
color Major: antennae and body rich light reddish brown ("coppery") except for the gaster, which is plain brown; legs yellow.
Range Known only from the type locality.
Biology Unknown.
Figure Upper: holotype, major. Lower: paratype, minor. BRAZIL: Utinga Tract, near Belem, Para (P. F. Darlington). Scale bars = 1 mm.
description: Published as part of Wilson, E. O., 2003, Pheidole in the New World. A dominant, hyperdiverse ant genus., Cambridge, MA :Harvard University Press on page 261
Pi-mesonic decay of the hypertriton
Creators: name: Kamada, H.
name: Golak, J.
name: Miyagawa, K.
name: Witala, H.
name: Gloeckle, W.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The pi-mesonic decay of the hypertriton is calculated based on a hypertriton wavefunction and 3N scattering states, which are rigorous solutions of 3-body Faddeev equations using realistic NN and hyperon-nucleon interactions. The total pi-mesonic decay rate is found to be 92% of the free Lambda decay rate, which is close to the experimental data. Together with the nonmesonic decay the total life time of 3Lambda H is predicted to be 2.78 x 10^-10 sec which is 6 % larger than for the free Lambda particle. The differential decay rate is evaluated as a function of the pion momentum. The decay into the N+d+pi channel is stronger than in the 3N+pi channel in contrast to the situation for the nonmesonic decay. The ratio for the decay rate into 3He + pi^- to the decay rate into all channels including pi^- is found to be 0.40, which is close to the experimental value. We visualise the decay into the dominant channel p+d+pi^- in a Dalitz plot. Finally we compare the polarisation of the outgoing proton in free unpolarised Lambda-decay to the polarisation of 3He in unpolarised 3_Lambda H-decay and we compare the closely related asymmetry of pi^- emitted parallel and antiparallel with respect to the spin-direction for a polarised Lambda to the corresponding asymmetry for a polarised 3_Lambda H.
description: 19pages, REVTeX, 9fugures
Mind Over Matter
Creators: name: Sarucco, Shalea
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 520202
subject: Behavioural neuroscience
classificationCode: 420313
subject: Mental health services
classificationCode: 520301
subject: Clinical neuropsychology
classificationCode: 320903
subject: Central nervous system
classificationCode: 320902
subject: Cellular nervous system
classificationCode: 320901
subject: Autonomic nervous system
classificationCode: 500320
subject: Psychoanalytic philosophy
classificationCode: 500312
subject: Philosophy of cognition
classificationCode: 500304
subject: Environmental philosophy

description: This study explores the impact of a negative self-image on adolescents’ physical health, focusing on stress, social influences, and psychosomatic symptoms. Through literature review and a survey of 16–18-year-olds, the research finds that chronic stress and low self-esteem contribute to fatigue, headaches, and sleep disturbances. Social media, school performance, and peer feedback significantly shape self-perception. The study also examines the Law of Attraction, suggesting that repeated negative thoughts reinforce poor well-being. Findings highlight the need for schools and communities to support self-confidence and mental health to reduce stress-related health issues.Nederlands:Dit onderzoek onderzoekt de impact van een negatief zelfbeeld op de fysieke gezondheid van jongeren, met focus op stress, sociale invloeden en psychosomatische klachten. Door middel van een literatuurstudie en een enquête onder 16- tot 18-jarigen blijkt dat chronische stress en een laag zelfbeeld bijdragen aan vermoeidheid, hoofdpijn en slaapproblemen. Sociale media, schoolprestaties en feedback van anderen spelen een grote rol in zelfperceptie. Daarnaast wordt de wet van aantrekking besproken, waarbij negatieve gedachten het welzijn verder kunnen beïnvloeden. De resultaten benadrukken het belang van ondersteuning door scholen en gemeenschappen om stress gerelateerde gezondheidsproblemen te verminderen.
Fluid simulations of plasma filaments in stellarator geometries with BSTING
Creators: name: Shanahan, B
name: Dudson, B
name: Hill, P
Publisher: name: arXiv
Year: 2018
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Here we present first results simulating plasma filaments in non-axisymmetric geometries, using a fluid turbulence extension of the \boutxx~framework. This is made possible by the implementation of the Flux Coordinate Independent scheme for parallel derivatives, an extension of the metric tensor components which allows them to vary in three dimensions, and development of grid generation. Tests have been performed to confirm that the extension to three dimensional metric tensors does not compromise the accuracy and stability of the associated numerical operators. Recent changes to the FCI grid generator in \boutxx, including a curvilinear grid system which allows for potentially more efficient computation, are also presented. Initial simulations of seeded plasma filaments in a non-axisymmetric geometry are reported. We characterize filaments propagating in the closed-field-line region of a low-field-period, rotating ellipse equilibrium as inertially-limited by examining the velocity scaling and currents associated with the filament propagation. Finally, it is shown that filaments in a non-axisymmetric rotating ellipse equilibrium propagate in a toroidally nonuniform fashion, and it is determined that the long connection lengths in the scrape-off-layer enable parallel gradients to establish, which has consequences for interpretation of experimental data.
Active site of (A) BC excinuclease. I. Evidence for 5'incision by UvrC through a catalytic site involving Asp399, Asp438, Asp466, and His538 residues.
Creators: name: Lin, Jing-Jer
name: Sancar, Aziz
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: (A)BC excinuclease of Escherichia coli removes damaged nucleotides from DNA by hydrolyzing the 8th phosphodiester bond 5' and the 15th phosphodiester bond 3' to the modified base. The activity results from the ordered action of UvrA, UvrB, and UvrC proteins. The role of UvrA is to help assemble the UvrB.DNA complex, and it is not involved in the actual incision reactions which are carried out by UvrB and UvrC. To investigate the role of UvrC in the nuclease activity a subset of His, Asp, and Glu residues in the C-terminal half of the protein were mutagenized in vitro. The effect of these mutations on UV resistance in vivo and incision activity in vitro were investigated. Mutations, H538F, D399A, D438A, and D466A conferred extreme UV sensitivity. Enzyme reconstituted with these mutant proteins carried out normal 3' incision but was completely defective in 5' incision activity. Our data suggest that UvrC makes the 5' incision by employing a mechanism whereby the three carboxylates acting in concert with H538 and a Mg2+ ion facilitate nucleophilic attack by an active site water molecule.
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 1055
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 1055, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 1055, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019