cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 7 of Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia
Creators: name: Pappalardo, Xena Giada
name: Risiglione, Pierpaolo
name: Zinghirino, Federica
name: Ostuni, Angela
name: Luciano, Daniela
name: Bisaccia, Faustino
name: De Pinto, Vito
name: Guarino, Francesca
name: Messina, Angela
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 7: Figure. S7. Mapping of the best putative promoters for the VDAC1P8 pseudogene (Promo 1-4) inferred by GeneHancer and found in Genecards (hg38). Genomic regions indicated in figure as Promo 1, 2, 3 and 4 correspond to putative VDAC1P8 promoters (GH06J142940, GH06J143449, GH06J143058, GH06J143842) selected from GeneCards ( https://www.genecards.org/cgi-bin/carddisp.pl?gene=VDAC1P8 ) with the best GH score (from 2.1 to 1.9). They map around the NCBI Refseq of VDAC1P8 gene and the transcript VDAC1P8-201 (ENST00000406025.2). All four putative promoters for VDAC1P8 fall within transcriptionally active chromatin regions as indicated by the levels of activating methylation at histone H3 (H3K4m1 and H3K4m3, histone H3 methyl-lysine 4 and histone H3 trimethyl-lysine 4, respectively). Bottom right, an enlargement of the genomic region between VDAC1P8 promoter 3 and the gene for the VDAC1P8-201 transcript, a region potentially under the control of the regulatory sequences of the adjacent genes ADAT2, PEX1 and FUCA2.
U-Park: A User-Centric Smart Parking Recommendation System for Electric Shared Micromobility Services
Creators: name: Yan, Sen
name: O'Connor, Noel E.
name: Liu, Mingming
Publisher: name: arXiv
Year: 2023
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Electric Shared Micromobility Services (ESMS) has become a vital element within the Mobility as a Service framework, contributing to sustainable transportation systems. However, existing ESMS face notable design challenges such as shortcomings in integration, transparency, and user-centred approaches, resulting in increased operational costs and decreased service quality. A key operational issue for ESMS revolves around parking, particularly ensuring the availability of parking spaces as users approach their destinations. For instance, a recent study illustrated that nearly 13% of shared E-Bike users in Dublin, Ireland, encounter difficulties parking their E-Bikes due to inadequate planning and guidance. In response, we introduce U-Park, a user-centric smart parking recommendation system designed for ESMS, providing tailored recommendations to users by analysing their historical mobility data, trip trajectory, and parking space availability. We present the system architecture, implement it, and evaluate its performance using real-world data from an Irish-based shared E-Bike provider, MOBY Bikes. Our results illustrate U-Park's ability to predict a user's destination within a shared E-Bike system, achieving an approximate accuracy rate of over 97.60%, all without requiring direct user input. Experiments have proven that this predictive capability empowers U-Park to suggest the optimal parking station to users based on the availability of predicted parking spaces, improving the probability of obtaining a parking spot by 24.91% on average and 29.66% on maximum when parking availability is limited.
description: The manuscript has been accepted by the IEEE Transactions on Artificial Intelligence. This manuscript includes 15 pages with 11 figures and 6 tables
Additional file 2 of Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety
Creators: name: Hauge, Mariann Saanum
name: Willumsen, Tiril
name: Stora, Bent
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Additional file 2. The Four Habits/midazolam treatment outline.
Pseudodifferential Operators on Noncommutative Tori: a Survey
Creators: name: Jiménez, Carolina Neira
Publisher: name: arXiv
Year: 2023
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 58B34, 53D55, 47G30

description: This article presents a survey of recent developments on pseudodifferential operators on noncommutative tori. We describe currently available constructions of those operators: by means of a $C^*$--dynamical system, by using an analogue of the Fourier series representation of a function in the (commutative) torus $C^\infty(\mathbb{T}^n)$, as Rieffel deformations of the standard pseudodifferential operators on $C^\infty(\mathbb{T}^n)$, and in association to certain spectral triples.
PyGenStability: Multiscale community detection with generalized Markov Stability
Creators: name: Arnaudon, Alexis
name: Schindler, Dominik J.
name: Peach, Robert L.
name: Gosztolai, Adam
name: Hodges, Maxwell
name: Schaub, Michael T.
name: Barahona, Mauricio
Publisher: name: arXiv
Year: 2023
Subjects: subject: Social and Information Networks (cs.SI)
subject: Mathematical Software (cs.MS)
subject: FOS: Computer and information sciences
subject: G.4; I.5.3

description: We present PyGenStability, a general-use Python software package that provides a suite of analysis and visualisation tools for unsupervised multiscale community detection in graphs. PyGenStability finds optimized partitions of a graph at different levels of resolution by maximizing the generalized Markov Stability quality function with the Louvain or Leiden algorithms. The package includes automatic detection of robust graph partitions and allows the flexibility to choose quality functions for weighted undirected, directed and signed graphs, and to include other user-defined quality functions.
Supplementary_Tables__20_Aug_2020_(1) – Supplemental material for Mental health and academic failure among first-year university students in South Africa
Creators: name: Bantjes, Jason
name: Wylene Saal
name: Gericke, Franco
name: Lochner, Christine
name: Roos, Janine
name: Auerbach, Randy P
name: Mortier, Philippe
name: Bruffaerts, Ronny
name: Kessler, Ronald C
name: Stein, Dan
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine

description: Supplemental material, Supplementary_Tables__20_Aug_2020_(1) for Mental health and academic failure among first-year university students in South Africa by Jason Bantjes, Wylene Saal, Franco Gericke, Christine Lochner, Janine Roos, Randy P Auerbach, Philippe Mortier, Ronny Bruffaerts, Ronald C Kessler and Dan Stein in South African Journal of Psychology
La Niña‐related coral death triggers biodiversity loss of associated communities in the Galápagos
Creators: name: Rhoades, O. Kennedy
name: Brandt, Margarita
name: Witman, Jon D.
Publisher: name: Wiley
Year: 2023

description:
During a cold La Niña period (August 2007–January 2008) in the central Galápagos archipelago, 70% of Pocillopora branching corals were severely bleached across three long‐term monitoring sites, affording an opportunity to examine its impact on the persistence of these corals and their associated community of fish and mobile macroinvertebrates. Using a time series empirical approach, we tagged and tracked the fate of 96 coral heads and their associates. When surveyed in July 2008, recovered live and dead corals that were previously severely bleached supported similar levels of species richness (randomized observed and estimated Chao 1). By contrast, richness on the surviving live corals remained fairly stable, while Chao 1 estimated richness on dead corals underwent a nearly 50% increase between July and January 2009, thereafter declining to 50% of originally surveyed richness by February 2010. This nonlinear change in species richness was largely due to an influx and decline in opportunistic generalists including pencil urchin bioeroders, gastropod snails, and hermit crabs that colonized dead corals and fed on sessile invertebrates and algae that had initially recruited to dead and undefended coral substrate. Thus, dead corals retained high overall species richness until live corals had recovered, after which richness declined as dead corals eroded and disintegrated (July 2011). Live corals attracted a less speciose but stable assemblage of mutualistic xanthid crabs and fishes that increased in abundance over time with the recovery and growth of live coral tissue. Overall, coral status (live/dead), planar area and maximum branch length predicted the number of species associated with each colony. The delayed diversity loss of associated species following La Niña disturbance to a foundation species represents a local extinction debt of 32–49‐month duration. A better understanding of the scale of extinction debt in foundational marine ecosystems is needed to quantify the breadth of impacts of climate oscillations on biodiversity and ecosystem functioning.
Additional file 5 of Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia
Creators: name: Pappalardo, Xena Giada
name: Risiglione, Pierpaolo
name: Zinghirino, Federica
name: Ostuni, Angela
name: Luciano, Daniela
name: Bisaccia, Faustino
name: De Pinto, Vito
name: Guarino, Francesca
name: Messina, Angela
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 5: Figure. S5. Multi-alignment between the VDAC1 mRNA and some VDAC1P8 alternative transcripts sequences. Alignment achieved by http://multalin.toulouse.inra.fr/multalin/ setting the default parameters. The regions with high consensus value (90% setting) are shown in red, while regions with low consensus value (50% setting) are shown in blue.
Additional file 1 of Pharmacologic inhibition of NLRP3 reduces the levels of α-synuclein and protects dopaminergic neurons in a model of Parkinson’s disease
Creators: name: Amo-Aparicio, Jesus
name: Daly, Jonathan
name: Højen, Jesper Falkesgaard
name: Dinarello, Charles A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health

description: Additional file 1: Figure S1. OLT1177 crosses the blood–brain barrier and reaches therapeutic concentrations. Figure S2. OLT1177 increases the clearance of α-synuclein oligomers by microglia in vitro. Figure S3. OLT1177 increases the levels of TREM2 after MPTP-acute administration.
“I mean, I didn't really have a choice of anything:” How incarceration influences abortion decision‐making and precludes access in the United States
Creators: name: Beal, Lauren
name: Kramer, Camille
name: Hayes, Crystal M.
name: Sufrin, Carolyn B.
name: Devon‐Williamston, Ashley
Publisher: name: Guttmacher Institute
Year: 2023

description:
OBJECTIVE: To understand how the punitive, rights-limiting, and racially stratified environment of incarceration in the United States (US) shapes the abortion desires, access, and pregnancy experiences of pregnant women, transgender men, and gender non-binary individuals. METHODS: From May 2018-November 2020, we conducted semi-structured, qualitative interviews with pregnant women in prisons and jails in an abortion supportive and an abortion restrictive state. Interviews explored whether participants considered abortion for this pregnancy; attempted to obtain an abortion in custody; whether and how incarceration affected their thoughts about pregnancy, birth, parenting, and abortion; and options counseling and prenatal care experiences, or lack thereof, in custody. RESULTS: The conditions of incarceration deeply shaped our 39 participants' abortion and pregnancy decisions, with some experiencing pregnancy continuation as punishment. Four themes emerged: (1) medical providers' overt obstruction of desired abortions; (2) participants assuming that incarcerated women had no right to abortion; (3) carceral bureaucracy constraining abortion access; and (4) carceral conditions made women wish they had aborted. Themes were similar in supportive and restrictive states. CONCLUSIONS: Incarceration shaped participants' thoughts about pregnancy and their abilities to access abortion, consider whether abortion was an attainable option, and make pregnancy-related decisions. These subtle carceral control aspects presented more frequent barriers to abortion than overt logistical ones. The carceral environment played a more significant role than the state's overall abortion climate in shaping abortion experiences. Incarceration constrains and devalues reproductive wellbeing in punitive ways that are a microcosm of broader forces of reproductive control in US society.
OpenSCV: An Open Hierarchical Taxonomy for Smart Contract Vulnerabilities
Creators: name: Vidal, Fernando Richter
name: Ivaki, Naghmeh
name: Laranjeiro, Nuno
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cryptography and Security (cs.CR)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Smart contracts are nowadays at the core of most blockchain systems, as they specify and allow an agreement between entities that wish to perform a transaction. As any computer program, smart contracts are subject to the presence of residual faults, including severe security vulnerabilities, which require that the vulnerable contract is terminated in the blockchain. In this context, research began to be developed to prevent the deployment of smart contract holding vulnerabilities, mostly in the form of vulnerability detection tools. Along with these efforts, several and heterogeneous vulnerability classification schemes arised (e.g., most notably DASP and SWC). At the time of writing, these are mostly outdated initiatives, despite the fact that smart contract vulnerabilities are continuously being discovered and the associated rich information being mostly disregarded. In this paper, we propose OpenSCV, a new and Open hierarchical taxonomy for Smart Contract Vulnerabilities, which is open to community contributions and matches the current state of the practice, while being prepared to handle future modifications and evolution. The taxonomy was built based on the analysis of research on vulnerability classification, community-maintained classification schemes, and research on smart contract vulnerability detection. We show how OpenSCV covers the announced detection ability of current vulnerability detection tools, and highlight its usefulness as a resource in smart contract vulnerability research.
Awareness and equity of behavioral sacrifice and same‐sex relationship quality: Heterosexist discrimination as a distal predictor
Creators: name: Curran, Melissa
name: Cao, Hongjian
name: Mills‐Koonce, W. Roger
name: Li, Xiaomin
name: Zhao, Zhenqiang
Publisher: name: Wiley
Year: 2023

description:
Objectives We included two sacrifice constructs to reflect the awareness and (in)equity of behavioral sacrifice in same‐sex relationships: (a) the receiver's awareness (whether the receiver under‐, over‐, or unbiasedly estimated the other's frequency of sacrifice behaviors) and (b) the provider's perceived (in)equity (whether the provider perceived themselves as underbenefitted, overbenefitted, or equitably treated). We then tested how heterosexist discrimination related to same‐sex couples' relationship quality via receivers' awareness and providers' perceived (in)equity. Background Sacrifices are pro‐relationship efforts in which individuals forgo self‐interests for the partner or the relationship. The links from sacrifice to same‐sex couples' relationship quality are still understudied. Further, no study has examined whether sexual minority stressors relate to sacrifice in same‐sex relationships. Method We used dyadic, survey data from 141 same‐sex couples and conducted actor–partner interdependence models. Results For receivers' awareness, unbiased estimation and overestimation were related to higher relationship quality; underestimation was related to lower relationship quality. For providers' perceived (in)equity, being underbenefitted—a situation in which individuals perceived that the other made fewer sacrifices than they did—was related to lower relationship quality. For indirect pathways, when one individual encountered heterosexist discrimination, this individual's sacrifice was likely underestimated by the receiver; in turn, this individual's partner experienced low relationship quality. Conclusions To better understand sacrifice and relationship quality for same‐sex couples, heterosexist discrimination should be considered. Implications Interventions are needed when practitioners work with same‐sex couples who feel that their sacrifices were underestimated, and efforts are still needed to reduce heterosexist discrimination.
Ecosystem Graphs: The Social Footprint of Foundation Models
Creators: name: Bommasani, Rishi
name: Soylu, Dilara
name: Liao, Thomas I.
name: Creel, Kathleen A.
name: Liang, Percy
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Foundation models (e.g. ChatGPT, StableDiffusion) pervasively influence society, warranting immediate social attention. While the models themselves garner much attention, to accurately characterize their impact, we must consider the broader sociotechnical ecosystem. We propose Ecosystem Graphs as a documentation framework to transparently centralize knowledge of this ecosystem. Ecosystem Graphs is composed of assets (datasets, models, applications) linked together by dependencies that indicate technical (e.g. how Bing relies on GPT-4) and social (e.g. how Microsoft relies on OpenAI) relationships. To supplement the graph structure, each asset is further enriched with fine-grained metadata (e.g. the license or training emissions). We document the ecosystem extensively at https://crfm.stanford.edu/ecosystem-graphs/. As of March 16, 2023, we annotate 262 assets (64 datasets, 128 models, 70 applications) from 63 organizations linked by 356 dependencies. We show Ecosystem Graphs functions as a powerful abstraction and interface for achieving the minimum transparency required to address myriad use cases. Therefore, we envision Ecosystem Graphs will be a community-maintained resource that provides value to stakeholders spanning AI researchers, industry professionals, social scientists, auditors and policymakers.
description: Authored by the Center for Research on Foundation Models (CRFM) at the Stanford Institute for Human-Centered Artificial Intelligence (HAI). Ecosystem Graphs available at https://crfm.stanford.edu/ecosystem-graphs/
From Private to Public: Benchmarking GANs in the Context of Private Time Series Classification
Creators: name: Mercier, Dominique
name: Dengel, Andreas
name: Ahmed, Sheraz
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Deep learning has proven to be successful in various domains and for different tasks. However, when it comes to private data several restrictions are making it difficult to use deep learning approaches in these application fields. Recent approaches try to generate data privately instead of applying a privacy-preserving mechanism directly, on top of the classifier. The solution is to create public data from private data in a manner that preserves the privacy of the data. In this work, two very prominent GAN-based architectures were evaluated in the context of private time series classification. In contrast to previous work, mostly limited to the image domain, the scope of this benchmark was the time series domain. The experiments show that especially GSWGAN performs well across a variety of public datasets outperforming the competitor DPWGAN. An analysis of the generated datasets further validates the superiority of GSWGAN in the context of time series generation.
description: 18 pages, 6 figures, 6 tables
Observation of the $Υ$(3S) meson and suppression of $Υ$ states in PbPb collisions at $\sqrt{s_\mathrm{NN}}$ = 5.02 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The production of $Υ$(2S) and $Υ$(3S) mesons in lead-lead (PbPb) and proton-proton (pp) collisions is studied in their dimuon decay channel using the CMS detector at the LHC. The $Υ$(3S) meson is observed for the first time in PbPb collisions, with a significance above five standard deviations. The ratios of yields measured in PbPb and pp collisions are reported for both the $Υ$(2S) and $Υ$(3S) mesons, as functions of transverse momentum and PbPb collision centrality. These ratios, when appropriately scaled, are significantly less than unity, indicating a suppression of $Υ$ yields in PbPb collisions. This suppression increases from peripheral to central PbPb collisions. Furthermore, the suppression is stronger for $Υ$(3S) mesons compared to $Υ$(2S) mesons, extending the pattern of sequential suppression of quarkonium states in nuclear collisions previously seen for the $ψ$/J, $ψ$(2S), $Υ$(1S), and $Υ$(2S) mesons.
description: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables, including additional supplementary figures and tables, can be found at http://cms-results.web.cern.ch/cms-results/public-results/publications/HIN-21-007 (CMS Public Pages)
Antiradical and anti-acethylcholinesterase constituents from the methylene chloride extract of Ganoderma applanatum (Pers.) Pat (Ganodermataceae) and molecular docking study
Creators: name: Feunaing, Roméo Toko
name: Yaya, Joël Abel Gbaweng
name: Nyemb, Jean Noël
name: Bassigue, Noël Issa
name: Ketsemen, Hervé Landry
name: Henoumont, Céline
name: Kandeda, Antoine Kavaye
name: Venditti, Alessandro
name: Laurent, Sophie
name: Talla, Emmanuel
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Biochemistry
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Alzheimer’s disease (AD) is a non-communicable disease with global impact. Inhibitors of acetylcholinesterase (AChE) are suitable therapies for AD. In this work, we report the isolation of antiacetylcholinesterase compounds from the methylene chloride (DCM) extract of the medical fungus Ganoderma applanatum (Pers.) Pat (Ganodermataceae). Chemical evaluation of this extract using chromatographic technics led to the isolation of a (1:1) mixture of ergosterol (1) and stellasterol (2), palmitic acid (3), ganodermanondiol (4), lucidumol B (5) and lupeol (6). Structures of these compounds were determined using spectroscopic analysis such as IR, MS, 1D & 2D NMR and literature. The acetylation reaction has been performed on the mixture (1 + 2) and compound 4, leading to the obtention the mixture of 3-acetyl-ergosterol (7) and 3-acetylstellasterol (8) along with 24-acetyl-ganodermanondiol (9) respectively. Total phenolic content was determined for DCM, Ethyl acetate and n-butanol extracts. To assess their antiradical scavenging potential, DPPH was used as free radical. The Inhibition power of acetylcholinesterase was evaluated in vitro using the Ellman reagent. Amongst all tested extracts, the DCM extract showed the high amount of total phenolic compounds with a value of 133.9512 mg EAG/g EX. The same extract showed a very good antiradical scavenging potential with an IC50 of 0.0021 mg/mL. The mixture (1 + 2) showed the highest antiradical scavenging activity with IC50 of 0.0770 mg/mL. The results obtained demonstrated that the acetylation has reduced the antiradical scavenging potential. Concerning the acetylcholinesterase inhibition power, the DCM extract and the mixture (1 + 2) showed a very good power with an inhibition percentage of 89%. The acetylation has also reduced the activity of the obtained derivative. The results provide insights into the potential efficacy of these compounds as acetylcholinesterase inhibitors. The binding interactions of the isolated and acetylated derivatives against acetylcholinesterase protein (PBP 3i6m) of Torpedo californica were studied using Autodock software. Ergosterol (−11.9 kcal/mol) binds better to the protein biding site through significant pi-sigma interactions.
Dynamical Coulomb Blockade as a Signature of the Sign-Reversing Cooper Pairing Potential
Creators: name: Liu, Chaofei
name: Portugal, Pedro
name: Gao, Yi
name: Yang, Jie
name: Zhang, Xiuying
name: Liu, Yanzhao
name: Wei, Tianheng
name: Ren, Wei
name: Lu, Jing
name: Flindt, Christian
name: Wang, Jian
Publisher: name: arXiv
Year: 2023
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Coulomb blockade occurs for electrons tunneling into nanoislands because of the quantization of charge. Here, using spectroscopy measurements of nonmagnetic islands grown on a high-Tc superconductor [one-unit-cell (1-UC) FeSe], we systematically investigate the dynamical Coulomb blockade (DCB), which is found to reflect the Cooper pairing potential in the superconducting substrate. The tunneling spectra are acquired on single-crystalline Pb nanoislands and show a clear suppression of the tunnel current around zero bias-voltage with a gap-like structure. The observed spectral gaps can be attributed to DCB based on our comprehensive investigations, including experiments with finely varying island sizes and calculations of the spectra using the P(E) theory of DCB. Our detailed analysis suggests that the observed DCB can be related to the sign-reversing pairing potential in the 1-UC FeSe substrate below the islands. The sign reversal is furthermore revealed in a transition of the superconducting gap of FeSe from a U- to a V-like lineshape as the distance between neighboring doublet islands is decreased, indicating the presence of a nodal-like gap as expected for a sign-reversing superconductor. Our configuration of nonmagnetic nanoislands on a high-Tc superconductor for spectroscopy measurements may serve as a local, spatially sensitive, and tunable probe for detecting the sign-reversing order parameter in unconventional superconductors.
Patient-centric no-option refractory angina management: establishing comprehensive angina relief (CARE) clinics
Creators: name: Rai, Balaj
name: Yildiz, Mehmet
name: Frizzell, Jarrod
name: Quesada, Odayme
name: Henry, Timothy D.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: Refractory angina (RA) is a debilitating condition characterized by persistent angina despite optimized medical therapy and limited options for further revascularization, leading to diminished quality of life and increased healthcare utilization. The RA patient population is rapidly expanding with significant unmet needs. Specialty clinics should be developed to focus on the long-term efficacy and safety of clinically available and novel treatment strategies, emphasizing quality of life. Patient-focused Comprehensive Angina Relief (CARE) clinics can enhance care and outcomes by providing individualized management for complex RA. This review summarizes peer-reviewed articles from PubMed and trial data from ClinicalTrials.gov. We discuss the epidemiology and pathophysiology of RA, introduce standardized tools for evaluating angina and psychosocial factors, and address symptom management. We also review treatment options such as risk factor modification, medication, and complex revascularization. Additionally, we explore emerging therapies, including coronary sinus occlusion, regenerative therapy, and neuromodulation for ‘no-option’ RA. In the next five years, patients with refractory chest pain with or without coronary artery disease will increasingly be referred to specialty clinics for follow-up. Conducting more randomized control clinical trials with larger population subsets will bring novel therapies to the forefront.
Knowledge, skills, and attitudes about diversity, equity, and inclusion among nurse educators
Creators: name: McMurray, Patrick
name: Fontenot, Justin
name: Valdez, Anna
name: Millan, Angelica
Publisher: name: Elsevier
Year: 2023

description:
Achieving health equity is a critical healthcare priority. Addressing health inequities will require that the nursing profession becomes more diverse, equitable, and inclusive. Nursing educators must be prepared to provide unbiased, inclusive, and accurate information about structural and social determinants of health. This cross-sectional exploratory study was conducted to evaluate the knowledge, skills, and attitudes of nurse educators related to diversity, equity, and inclusion. A researcher-designed survey was distributed to Associate Degree in Nursing programs across the United States. Study participants (n = 318) were primarily white, cisgender, heterosexual females, which is representative of the nursing profession. Findings from this study indicate that there is significant work to be done to address diversity, equity, and inclusion in both nursing education practice and curricular content. Nurse educators play a critical role in shaping the future of health care. Nursing faculty should use the findings of this study to examine their personal biases, institutional policies and procedures, and nursing program curricular content.
Additional file 1 of Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety
Creators: name: Hauge, Mariann Saanum
name: Willumsen, Tiril
name: Stora, Bent
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Additional file 1. The D-CBT manual. Detailed description of the D-CBT treatment condition.
Moving Toward Diversity, Equity, and Inclusion: Barriers, Consequences, and Solutions
Creators: name: Li, Su-Ting T
name: Corley, Alexandra M S
name: Raphael, Jean L
name: Lopez, Michelle A
name: Klein, Melissa
name: Gustafson, Sarah
name: Pitt, Michael B
name: Tatem, Andria
name: Orr, Colin J
Publisher: name: Elsevier
Year: 2023

description:
In this issue of Academic Pediatrics, we present a collection of 11 educational innovations that have the potential to foster antiracist learning in clinical environments.Educational efforts to address antiracism align within broader initiatives to prioritize and implement diversity, equity, and inclusion (DEI) across pediatric academic and  clinical landscapes.
Additional file 4 of Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety
Creators: name: Hauge, Mariann Saanum
name: Willumsen, Tiril
name: Stora, Bent
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Additional file 4. The study flow diagram shows the process of inclusion and exclusion of participants as well as drop-out and loss of data during the study course.
Health promotion, the social determinants of health, and urban health: what does a critical discourse analysis of World Health Organization texts reveal about health equity?
Creators: name: Bump, Jesse Boardman
name: Enright, Theresa
name: Siddiqi, Arjumand
name: O’Campo, Patricia
name: Di Ruggiero, Erica
name: Amri, Michelle
Publisher: name: Springer Nature
Year: 2023

description:
Background The World Health Organization (WHO) has focused on health equity as part of its mandate and broader agenda—consider for example, the “health for all” slogan. However, a recent scoping review determined that there are no studies that investigate the WHO’s approach to health equity. Therefore, this study is the first such empirical analysis examining discourses of health equity in WHO texts concerning health promotion, the social determinants of health, and urban health. Methods We undertook a critical discourse analysis of select texts that concern health promotion, the social determinants of health, and urban health. Results The findings of this study suggest that (i) underpinning values are consistent in WHO texts’ approach to health equity; (ii) WHO texts reiterate that health inequities are socially constructed and mitigatable but leave the ‘causes of causes’ vague; (iii) despite distinguishing between health “inequities” and “inequalities,” there are several instances where these terms are used interchangeably across texts; (iv) WHO texts approach health equity broadly (covering a variety of areas); (v) health equity may be viewed as applicable either throughout the life-course or intergenerationally, which depends on the specific WHO text at hand; and (vi) WHO texts at times use vague or unclear language around how to improve health equity. Conclusions This study does not present one definition of health equity and action to be taken. Instead, this study uncovers discourses embedded in WHO texts to spur discussion and deliberate decision-making. This work can also pave the way for further inquiry on other complex key terms or those with embedded values.
Additional file 6 of Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety
Creators: name: Hauge, Mariann Saanum
name: Willumsen, Tiril
name: Stora, Bent
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Additional file 6. Normality tests. The tables show tests of normality for the data collected in the study.
Isolation and characterization of probiotics from sweet toddy and evaluation of their potential pharmaceutical applications
Creators: name: Velmurugan, Thangavel
name: Rajeshkumar, Mohan Prasanna
name: Kowsalya, Mariyappan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: The increasing demand for natural and functional foods has accelerated research in the field of probiotics, with a focus on indigenous sources of beneficial microorganisms. This study investigates the isolates that contain probiotic characteristics from Sweet Toddy. The seven isolates were evaluated for key probiotic qualities, such as resistance to bile salts, simulated gastric juice, NaCl, and low pH environments. Based on these studies, two isolates were selected for further characterisation of autoaggregation, antibacterial activity, antibiotic susceptibility, and haemolytic activity. The results showed that both isolates had high tolerance to simulated gastrointestinal diseases as well as antibacterial properties and were susceptible to several antibiotics. Importantly, both strains showed γ-haemolytic activity, confirming their safety profile. Molecular identification confirmed the isolates as Bacillus licheniformis (PP724383) and Bacillus hyanesii (PP762189). The results suggest that these strains have great potential as probiotics with applications in functional food development and the pharmaceutical industry.
Rebuilding a Reproductive Future Informed by Disability and Reproductive Justice
Creators: name: Hassan, Asha
name: Hirz, Alanna E
name: Yates, Lindsey
name: Hing, Anna K
Publisher: name: Elsevier
Year: 2023

description:
Access to legal abortion has eroded significantly since the June 2022 Dobbs v. Jackson Women’s Health Organization Supreme Court ruling, which reversed the previously acknowledged constitutional right to abortion (Rader et al., 2022). Since then, threats to abortion access have continued with state and federal court and legislative challenges (Cohen, Donley, & Rebouche, 2023). Researchers, policy makers, and practitioners have focused on how restrictions disproportionately harm the most vulnerable, including minors, people living in poverty,  immigrants, racialized people, and people with disabilities (Hassan et al., 2022; Kozhimannil et al., 2022; Ogbu-Nwobodo et al., 2022). This shift is noteworthy given the missteps of the past; reproductive health and rights frameworks have historically failed to center these populations in both clinical decisionmaking and policy (Nourse, 2011). In a post-Dobbs world, as modes of care and access change and transform, equity conscious stakeholders can and should re-define what justice-informed reproductive health care is, how it is operationalized, and who it empowers.
Definitions, terminology, and related concepts of “racial health equity”: a scoping review protocol
Creators: name: Riddle, Dru
name: Welch, Vivian A.
name: Turner, Robert W.
name: Baker, Tamara A.
name: Terhune, Elizabeth A.
name: Dagne, Mahederemariam Bayleyegn
name: Viswanathan, Meera
name: Piper, Christi
name: Duque, Tiffany
name: Ovelman, Colleen
name: Heyn, Patricia C.
name: Rizvi, Anita
name: Pizarro, Ana B.
name: Dewidar, Omar
name: Sathe, Nila
name: Francis, Damian
Publisher: name: Springer Nature
Year: 2023

description:
Background In the USA, access to quality healthcare varies greatly across racial and ethnic groups, resulting in significant health disparities. A new term, “racial health equity” (RHE), is increasingly reported in the medical literature, but there is currently no consensus definition of the term. Additionally, related terms such as “health disparities,” “health inequities,” and “equality” have been inconsistently used when defining RHE. Methods The primary purpose of this scoping review is to investigate the current use and underlying concepts used to define racial health equity. The study will address two key questions: (1) “What terminology and definitions have been used to characterize RHE?” and (2) “What knowledge gaps and challenges are present in the current state of RHE research and theory?” The review will collect and analyze data from three sources: (1) websites from key national and international health organizations, (2) theoretical and narrative published articles, and (3) evidence synthesis studies addressing interventions targeting racial health equity and minority stakeholder engagement. Discussion Defining “racial health equity” and related terminology is the first step to advancing racial health equity within the USA. This review aims to offer an improved understanding of RHE constructs and definitions, bringing greater unity to national racial health equity research efforts across disciplines. Systematic review registration This protocol is registered with the Open Science Framework at https://osf.io/7pvzq.
Novel sesquiterpenoids from Colletotrichum camelliae LP76, a predominant endophytic fungus from Camellia taliensis
Creators: name: Fu, Xiaoman
name: Shu, Yuancao
name: Zhang, Zhiyu
name: Wang, Weihua
name: Xie, Sida
name: Yang, Xiaoqin
name: Zhang, Yingjun
name: Zhao, Ping
name: Zhu, Guolei
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Two new sesquiterpenoids, designated as collcameins A (1) and B (2), alongside four previously identified compounds (3-6), were successfully extracted from the solid-state fermentation of Colletotrichum camelliae LP76, a predominant endophytic fungus found within its leaves of Camellia taliensis cultivated ancient tea tree. Their chemical structures were determined through various spectroscopic techniques and by comparing the results with available literature for elucidation. To clarify the stereochemical configurations of 1 and 2, extra X-ray diffraction crystallography was employed, both featuring a rare presilphiperfolane-type architecture. Additionally, the anti-inflammatory and antifungal activities were also assessed. As a result, compound 1 and 2 exhibited significant inhibitions against A. brassicicola, being comparable with the positive control (thiabendazole).
Quantum Spin Supersolid as a precursory Dirac Spin Liquid in a Triangular Lattice Antiferromagnet
Creators: name: Jia, Haichen
name: Ma, Bowen
name: Wang, Zidan
name: Chen, Gang
Publisher: name: arXiv
Year: 2023
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Based on the recent experiments on the triangular lattice antiferromagnet Na$_2$BaCo(PO$_4$)$_2$, we propose the easy-axis XXZ spin-1/2 model on the triangular lattice, that exhibits a quantum spin supersolid, to be a precursory Dirac spin liquid. Despite the presence of a three-sublattice magnetic order as a spin supersolid, we suggest that this system is close to a Dirac spin liquid by exploring its spectroscopic response. The physical consequence is examined from the spectroscopic response, and we establish the continuous spectra near the M point in addition to the K point excitation from the spinon continuum on top of the three-sublattice order. Moreover, the satellite peaks were predicted at the mid-points connecting the $Γ$ and K points. This proposal offers a plausible understanding of the recent inelastic neutron scattering measurement in Na$_2$BaCo(PO$_4$)$_2$ and could inspire further research in relevant models and materials, such as K$_2$Co(SeO$_3$)$_2$ and Rb$_2$Co(SeO$_3$)$_2$, and even more anisotropic magnets like PrMgAl$_{11}$O$_{19}$.
description: 13 pages, 9 figures. To appear in Phys Rev Research
Characterizing age- and sex-related differences in brain structure among middle-aged and older Hispanic/Latino adults in the study of Latinos- investigation of neurocognitive aging magnetic resonance imaging (SOL-INCA MRI)
Creators: name: Lipton, Richard B.
name: Isasi, Carmen R.
name: Kaplan, Robert
name: DeCarli, Charles
name: Paredes, Alejandra Morlett
name: Zeng, Donglin
name: Cai, Jianwen
name: Gellman, Marc D.
name: Tarraf, Wassim
name: Ivanovic, Vladamir
name: Ramos, Alberto R.
name: Gallo, Linda C.
name: Testai, Fernando D.
name: González, Hector M.
name: Talavera, Gregory A.
name: Lamar, Melissa
name: Daviglus, Martha
name: Stickel, Ariana M.
name: González, Kevin A.
Publisher: name: Elsevier
Year: 2023

description:
Hispanic/Latino adults are a growing segment of the older U.S. population yet are underrepresented in brain aging research. We aimed to characterize brain aging among diverse Hispanic/Latino individuals. Hispanic/Latino individuals (unweighted n = 2273 ages 35-85 years; 56% female) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) population-based study underwent magnetic resonance imaging (MRI) as part of the SOL- Investigation of Neurocognitive Aging MRI (SOL-INCA-MRI) ancillary study (2018-2022). We performed linear regressions to calculate age associations with brain volumes for each outcome (total (global) brain, hippocampal, lateral ventricle, total white matter hyperintensity (WMH), individual cortical lobar, and total cortical gray matter) and tested modification by sex. Older age was associated with smaller gray matter volumes and larger lateral ventricle and WMH volumes. Age-related differences in global brain volumes and gray matter volumes in specific regions (i.e., the hippocampus and temporal and occipital lobes) were less pronounced among women. Our findings warrant further investigation into sex-specific mechanisms of brain aging using longitudinal studies.
Characterising transformations between quantum objects, 'completeness' of quantum properties, and transformations without a fixed causal order
Creators: name: Milz, Simon
name: Quintino, Marco Túlio
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Many fundamental and key objects in quantum mechanics are linear mappings between particular affine/linear spaces. This structure includes basic quantum elements such as states, measurements, channels, instruments, non-signalling channels and channels with memory, and also higher-order operations such as superchannels, quantum combs, n-time processes, testers, and process matrices which may not respect a definite causal order. Deducing and characterising their structural properties in terms of linear and semidefinite constraints is not only of foundational relevance, but plays an important role in enabling the numerical optimisation over sets of quantum objects and allowing simpler connections between different concepts and objects. Here, we provide a general framework to deduce these properties in a direct and easy to use way. While primarily guided by practical quantum mechanical considerations, we also extend our analysis to mappings between general linear/affine spaces and derive their properties, opening the possibility for analysing sets which are not explicitly forbidden by quantum theory, but are still not much explored. Together, these results yield versatile and readily applicable tools for all tasks that require the characterisation of linear transformations, in quantum mechanics and beyond. As an application of our methods, we discuss how the existence of indefinite causality naturally emerges in higher-order quantum transformations and provide a simple strategy for the characterisation of mappings that have to preserve properties in a 'complete' sense, i.e., when acting non-trivially only on parts of an input space.
description: 45 pages, 15 figures, accepted for publication in Quantum
Local geometry and quantum geometric tensor of mixed states
Creators: name: Hou, Xu-Yang
name: Zhou, Zheng
name: Wang, Xin
name: Guo, Hao
name: Chien, Chih-Chun
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: The quantum geometric tensor (QGT) is a fundamental concept for characterizing the local geometry of quantum states. After casting the geometry of pure quantum states and extracting the QGT, we generalize the geometry to mixed quantum states via the density matrix and its purification. The gauge-invariant QGT of mixed states is derived, whose real and imaginary parts are the Bures metric and the Uhlmann form, respectively. In contrast to the imaginary part of the pure-state QGT that is proportional to the Berry curvature, the Uhlmann form vanishes identically for ordinary physical processes. Moreover, there exists a Pythagorean-like equation that links different local distances and reflect the underlying fibration. The Bures metric of mixed states is shown to reduce to the corresponding Fubini-Study metric of the ground state as temperature approaches zero, establishing a correspondence despite the different underlying fibrations. We also present two examples with contrasting local geometries and discuss experimental implications.
description: 24 pages, 3 figures
sj-pdf-2-jhs-10.1177_1753193420914762 - Supplemental material for BSSH Spring Meeting Abstracts
Creators: name: Lu, Justin D.
name: Muskaan Sachdeva
name: Vender, Ronald
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-2-jhs-10.1177_1753193420914762 for BSSH Spring Meeting Abstracts by in Journal of Hand Surgery (European Volume)