cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Giant magnetoresistance and spin Seebeck coefficient in zigzag a-graphyne nanoribbons
Creators: name: Zhai, M. X.
name: Wang, X. F.
name: Vasilopoulos, P.
name: Liu, Y. S.
name: Dong, Y. J.
name: Zhou, L.
name: Jiang, Y. J.
name: You, W. L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the spin-dependent electric and thermoelectric properties of ferromagnetic zigzag-graphyne nanoribbons (ZGNRs) using the density-functional theory combined with the non-equilibrium Green's function method. A giant magnetoresistance is obtained in the pristine even-width ZGNRs and can be as high as 10e6 %. However, for the doped systems, a large magnetoresistance behavior may appear in the odd-width ZGNRs rather than the even-width ones. This suggests that the magnetoresistance can be manipulated in a wide range by the dopants on edges of ZGNRs. Another interesting phenomenon is that in the B- and N-doped even-width ZGNRs the spin Seebeck coefficient is always larger than the charge Seebeck coefficient, and a pure-spin-current thermospin device can be achieved at specific temperatures.
Canadian Gallup Poll # 282
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); US foreign policy(2); war emergency, bomb shelters(5); federal government job performance(3); anti-semitism(1); resurgence of nazism in Germany(2); Canada-US relations(2); political parties(4); opposition party job performance(1). Note: Demographics(11).
Quantum spin liquid in the Ising triangular-lattice antiferromagnet neodymium heptatantalate
Creators: name: Arh, T.
name: Sana, B.
name: Pregelj, M.
name: Khuntia, P.
name: Jagličić, Z.
name: Le, M. D.
name: Biswas, P.
name: Ozarowski, A.
name: Zorko, A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Disordered magnetic states known as spin liquids are of paramount importance in both fundamental and applied science. A classical state of this kind was predicted for the Ising antiferromagnetic triangular model more than half a century ago, while additional non-commuting exchange terms were proposed to induce its quantum version -- a quantum spin liquid. These predictions have not been yet confirmed experimentally. Here we report a discovery of such a state in the structurally perfect triangular-lattice antiferromagnet NdTa$_7$O$_{19}$. Its magnetic ground state is characterized by spin-1/2 degrees of freedom with Ising-like interactions and gives rise to low-frequency spin excitations persisting down to the lowest temperatures. Our study demonstrates the key role of strong spin-orbit coupling in stabilizing spin liquids that result from magnetic anisotropy and highlights the large family of rare-earth (RE) heptatantalates RETa$_7$O$_{19}$ as a novel framework for realization of these states, which represent a promising platform for quantum applications.
description: This is the initially submitted version of the manuscript, the considerably extended and revised published version is available online at https://doi.org/10.1038/s41563-021-01169-y
Histo-Blood Group Gene Polymorphisms as Potential Genetic Modifiers of Infection and Cystic Fibrosis Lung Disease Severity
Creators: name: Taylor-Cousar, Jennifer L.
name: Wright, Fred A.
name: Knowles, Michael R.
name: Calloway, Hollin
name: Burch, Lauranell H.
name: Zariwala, Maimoona A.
name: Drumm, Mitchell L.
name: Weston, Brent W.
name: Pace, Rhonda G.
name: Fan, Haiying
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundThe pulmonary phenotype in cystic fibrosis (CF) is variable; thus, environmental and genetic factors likely contribute to clinical heterogeneity. We hypothesized that genetically determined ABO histo-blood group antigen (ABH) differences in glycosylation may lead to differences in microbial binding by airway mucus, and thus predispose to early lung infection and more severe lung disease in a subset of patients with CF.Methods and Principal FindingsClinical information and DNA was collected on >800 patients with the ΔF508/ΔF508 genotype. Patients in the most severe and mildest quartiles for lung phenotype were enrolled. Blood samples underwent lymphocyte transformation and DNA extraction using standard methods. PCR and sequencing were performed using standard techniques to identify the 9 SNPs required to determine ABO blood type, and to identify the four SNPs that account for 90–95% of Lewis status in Caucasians. Allele identification of the one nonsynonymous SNP in FUT2 that accounts for >95% of the incidence of nonsecretor phenotype in Caucasians was completed using an ABI Taqman assay. The overall prevalence of ABO types, and of FUT2 (secretor) and FUT 3 (Lewis) alleles was consistent with that found in the Caucasian population. There was no difference in distribution of ABH type in the severe versus mild patients, or the age of onset of Pseudomonas aeruginosa infection in the severe or mild groups. Multivariate analyses of other clinical phenotypes, including gender, asthma, and meconium ileus demonstrated no differences between groups based on ABH type.Conclusions and SignificancePolymorphisms in the genes encoding ABO blood type, secretor or Lewis genotypes were not shown to associate with severity of CF lung disease, or age of onset of P. aeruginosa infection, nor was there any association with other clinical phenotypes in a group of 808 patients homozygous for the ΔF508 mutation.
title: Gulf War Syndrome Collection
Creators: name: Uniformed Services University of the Health Sciences
Publisher: name: University Archives, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814
Year: 2010
Subjects: classificationCode: 3
subject: FOS: Medical and health sciences
classificationCode: 6.1
subject: FOS: History and archaeology

description: USUHS Archives Finding Aid
Gulf War Syndrome Collection
2010
Extreme Negative Dependence and Risk Aggregation
Creators: name: Wang, Bin
name: Wang, Ruodu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We introduce the concept of an extremely negatively dependent (END) sequence of random variables with a given common marginal distribution. The END structure, as a new benchmark for negative dependence, is comparable to comonotonicity and independence. We show that an END sequence always exists for any given marginal distributions with a finite mean and we provide a probabilistic construction. Through such a construction, the partial sum of identically distributed but dependent random variables is controlled by a random variable that depends only on the marginal distribution of the sequence. The new concept and derived results are used to obtain asymptotic bounds for risk aggregation with dependence uncertainty.
Plethysm and the algebra of uniform block permutations
Creators: name: Orellana, Rosa
name: Saliola, Franco
name: Schilling, Anne
name: Zabrocki, Mike
Publisher: name: arXiv
Year: 2021
Subjects: subject: Combinatorics (math.CO)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 05E10, 05E05

description: We study the representation theory of the uniform block permutation algebra in the context of the representation theory of factorizable inverse monoids. The uniform block permutation algebra is a subalgebra of the partition algebra and is also known as the party algebra. We compute its characters and provide a Frobenius characteristic map to symmetric functions. This reveals connections of the characters of the uniform block permutation algebra and plethysms of Schur functions.
description: 45 pages; incorporated comments by referee, corrected character tables in Section 5
In Silico Generation of Alternative Hypotheses Using Causal Mapping (CMAP)
Creators: name: Kapustina, Maryna T.
name: Weinreb, Gabriel E.
name: Jacobson, Ken
name: Elston, Timothy C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Previously, we introduced causal mapping (CMAP) as an easy to use systems biology tool for studying the behavior of biological processes that occur at the cellular and molecular level. CMAP is a coarse-grained graphical modeling approach in which the system of interest is modeled as an interaction map between functional elements of the system, in a manner similar to portrayals of signaling pathways commonly used by molecular cell biologists. CMAP describes details of the interactions while maintaining the simplicity of other qualitative methods (e.g., Boolean networks).
High performance current and spin diode of atomic carbon chain between transversely symmetric ribbon electrodes
Creators: name: Dong, Y. J.
name: Wang, X. F.
name: Yang, S. W.
name: Wu, X. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate that giant current and high spin rectification ratios can be achieved in atomic carbon chain devices connected between two symmetric ferromagnetic zigzag-graphene-nanoribbon electrodes. The spin dependent transport simulation is carried out by density functional theory combined with the non-equilibrium Green's function method. It is found that the transverse symmetries of the electronic wave functions in the nanoribbons and the carbon chain are critical to the spin transport modes. In the parallel magnetization configuration of two electrodes, pure spin current is observed in both linear and nonlinear regions. However, in the antiparallel configuration, the spin-up (down) current is prohibited under the positive (negative) voltage bias, which results in a spin rectification ratio of order 104. When edge carbon atoms are substituted with boron atoms to suppress the edge magnetization in one of the electrodes, we obtain a diode with current rectification ratio over 10e6.
INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis
Creators: name: Ibrahim, Joseph G.
name: Mohlke, Karen L.
name: Torrice, Chad
name: Burd, Christin E.
name: Sharpless, Norman E.
name: Sanoff, Hanna K.
name: Liu, Yan
name: Thomas, Nancy E.
name: Cho, Hyunsoon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundGenome-wide association studies (GWAS) have linked common single nucleotide polymorphisms (SNPs) on chromosome 9p21 near the INK4/ARF (CDKN2A/B) tumor suppressor locus with risk of atherosclerotic diseases and type 2 diabetes mellitus. To explore the mechanism of this association, we investigated whether expression of proximate transcripts (p16INK4a, p15INK4b, ARF, ANRIL and MTAP) correlate with genotype of representative 9p21 SNPs.Methodology/Principal FindingsWe analyzed expression of 9p21 transcripts in purified peripheral blood T-cells (PBTL) from 170 healthy donors. Samples were genotyped for six selected disease-related SNPs spanning the INK4/ARF locus. Correlations among these variables were determined by univariate and multivariate analysis. Significantly reduced expression of all INK4/ARF transcripts (p15INK4b, p16INK4a, ARF and ANRIL) was found in PBTL of individuals harboring a common SNP (rs10757278) associated with increased risk of coronary artery disease, stroke and aortic aneurysm. Expression of MTAP was not influenced by rs10757278 genotype. No association of any these transcripts was noted with five other tested 9p21 SNPs.Conclusions/SignificanceGenotypes of rs10757278 linked to increased risk of atherosclerotic diseases are also associated with decreased expression in PBTL of the INK4/ARF locus, which encodes three related anti-proliferative transcripts of known importance in tumor suppression and aging.
Observability, Dominance, and Induction in Learning Models
Creators: name: Clark, Daniel
name: Fudenberg, Drew
name: He, Kevin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Theoretical Economics (econ.TH)
subject: FOS: Economics and business

description: Learning models do not in general imply that weakly dominated strategies are irrelevant or justify the related concept of "forward induction," because rational agents may use dominated strategies as experiments to learn how opponents play, and may not have enough data to rule out a strategy that opponents never use. Learning models also do not support the idea that the selected equilibria should only depend on a game's normal form, even though two games with the same normal form present players with the same decision problems given fixed beliefs about how others play. However, playing the extensive form of a game is equivalent to playing the normal form augmented with the appropriate terminal node partitions so that two games are information equivalent, i.e., the players receive the same feedback about others' strategies.
Intestinal Epithelial-Derived TAK1 Signaling Is Essential for Cytoprotection against Chemical-Induced Colitis
Creators: name: Kajino-Sakamoto, Rie
name: Kim, Jae-Young
name: Jobin, Christian
name: Ninomiya-Tsuji, Jun
name: Omori, Emily
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundWe have previously reported that intestinal epithelium-specific TAK1 deleted mice exhibit severe inflammation and mortality at postnatal day 1 due to TNF-induced epithelial cell death. Although deletion of TNF receptor 1 (TNFR1) can largely rescue those neonatal phenotypes, mice harboring double deletion of TNF receptor 1 (TNFR1) and intestinal epithelium-specific deletion of TAK1 (TNFR1KO/TAK1IEKO) still occasionally show increased inflammation. This indicates that TAK1 is important for TNF-independent regulation of intestinal integrity.Methodology/Principal FindingsIn this study, we investigated the TNF-independent role of TAK1 in the intestinal epithelium. Because the inflammatory conditions were sporadically developed in the double mutant TNFR1KO/TAK1IEKO mice, we hypothesize that epithelial TAK1 signaling is important for preventing stress-induced barrier dysfunction. To test this hypothesis, the TNFR1KO/TAK1IEKO mice were subjected to acute colitis by administration of dextran sulfate sodium (DSS). We found that loss of TAK1 significantly augments DSS-induced experimental colitis. DSS induced weight loss, intestinal damages and inflammatory markers in TNFR1KO/TAK1IEKO mice at higher levels compared to the TNFR1KO control mice. Apoptosis was strongly induced and epithelial cell proliferation was decreased in the TAK1-deficient intestinal epithelium upon DSS exposure. These suggest that epithelial-derived TAK1 signaling is important for cytoprotection and repair against injury. Finally, we showed that TAK1 is essential for interleukin 1- and bacterial components-induced expression of cytoprotective factors such as interleukin 6 and cycloxygenase 2.ConclusionsHomeostatic cytokines and microbes-induced intestinal epithelial TAK1 signaling regulates cytoprotective factors and cell proliferation, which is pivotal for protecting the intestinal epithelium against injury.
I demoni nella filosofia di Girolamo Cardano
Creators: name: Cesco-Frare, Laura
Publisher: name: Universita degli studi di Salerno
Year: 2022
Subjects: subject: M-FIL/06 STORIA DELLA FILOSOFIA
subject: Girolamo Cardano
subject: Demoni
subject: Filosofia

description: 2020 - 2021
description: Il lavoro indaga la riflessione filosofica proposta dal medico e filosofo Girolamo Cardano (1501-1576) sul tema dei demoni e sottolinea, in particolare, come le considerazioni teoretiche si intreccino con l'esperienza autobiografica dell'autore. La tesi analizza un buon numero di opere cardaniane, la maggior parte delle quali inedite, e fornisce la traduzione italiana (corredata dal testo latino) dei passi esaminati. Il materiale è ripartito in quattro capitoli analitici, seguiti da un quinto capitolo che riassume i principali nodi teorici della ricerca. .. [a cura dell'Autore]
description: The aim of this dissertation is to shed light on the philosophical approach to demons envisioned by the physician and philosopher Girolamo Cardano (1501-1576), focusing in particular on how the author's theory is intertwined with his own personal experience. Most of the selected passages taken into consideration in this work are translated in Italian for the first time; the original Latin version, while often lacking a critical edition, is always presented alongside the translation. The dissertation is composed of four analytical chapters, followed by a fifth one which consists in a summary of the main results. .. [edited by Author]
Canadian Gallup Poll # 297
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Upcoming federal election: interest, vote intent(5); past federal elections vote(1); Canada's defense policies(1); A-bomb tests(1); church/synagogue attendance(1); devaluation of Canadian dollar(2); TV and children(1). Note: Demographics(14).
Boson Stars with Nontrivial Topology
Creators: name: Dzhunushaliev, Vladimir
name: Folomeev, Vladimir
name: Hoffmann, Christian
name: Kleihaus, Burkhard
name: Kunz, Jutta
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We construct boson star solutions in the presence of a phantom field, allowing for a nontrivial topology of the solutions. The wormholes residing at the core of the configurations lead to a number of qualitative changes of the boson star solutions. In particular, the typical spiraling dependence of the mass and the particle number on the frequency of the boson stars is lost. Instead, the boson stars with nontrivial topology approach a singular configuration in the limit of vanishing frequency. Depending on the value of the coupling constant, the wormhole geometry changes from a single throat configuration to a double throat configuration, featuring a belly inbetween the two throats. Depending on the mass of the boson field and its self-interaction, the mass and the size of these objects cover many orders of magnitude, making them amenable to various astrophysical observations. A stability analysis reveals, that the unstable mode of the Ellis wormhole is retained in the presence of the bosonic matter. However, the negative eigenvalue can get very close to zero, by tuning the parameters of the self-interaction potential appropriately.
description: 21 pages, 9 figures
Is HIV Infection a Risk Factor for Multi-Drug Resistant Tuberculosis? A Systematic Review
Creators: name: Van Rie, Annelies
name: Suchindran, Sujit
name: Brouwer, Emily S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundTuberculosis (TB) is an important cause of human suffering and death. Human immunodeficiency virus (HIV), multi-drug resistant TB (MDR-TB), and extensive drug resistant tuberculosis (XDR-TB) have emerged as threats to TB control. The association between MDR-TB and HIV infection has not yet been fully investigated. We conducted a systematic review and meta-analysis to summarize the evidence on the association between HIV infection and MDR-TB.Methods and ResultsOriginal studies providing Mycobacterium tuberculosis resistance data stratified by HIV status were identified using MEDLINE and ISI Web of Science. Crude MDR-TB prevalence ratios were calculated and analyzed by type of TB (primary or acquired), region and study period. Heterogeneity across studies was assessed, and pooled prevalence ratios were generated if appropriate. No clear association was found between MDR-TB and HIV infection across time and geographic locations. MDR-TB prevalence ratios in the 32 eligible studies, comparing MDR-TB prevalence by HIV status, ranged from 0.21 to 41.45. Assessment by geographical region or study period did not reveal noticeable patterns. The summary prevalence ratios for acquired and primary MDR-TB were 1.17 (95% CI 0.86, 1.6) and 2.72 (95% CI 2.03, 3.66), respectively. Studies eligible for review were few considering the size of the epidemics. Most studies were not adjusted for confounders and the heterogeneity across studies precluded the calculation of a meaningful overall summary measure.ConclusionsWe could not demonstrate an overall association between MDR-TB and HIV or acquired MDR-TB and HIV, but our results suggest that HIV infection is associated with primary MDR-TB. Future well-designed studies and surveillance in all regions of the world are needed to better clarify the relationship between HIV infection and MDR-TB.
Canadian Gallup Poll # 328
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Upcoming federal election: interest, vote intent, predicted winner(5); past federal elections vote(1); opposition leaders job performance(2); current party preference(1); euthanasia(2); best choice for Prime Minister(1); morals(8); opinion about young people(12). Note: Demographics(11).
Loss of the Histone Pre-mRNA Processing Factor Stem-Loop Binding Protein in Drosophila Causes Genomic Instability and Impaired Cellular Proliferation
Creators: name: Salzler, Harmony R.
name: Davidson, Jean M.
name: Montgomery, Nathan D.
name: Duronio, Robert J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundMetazoan replication-dependent histone mRNAs terminate in a conserved stem-loop structure rather than a polyA tail. Formation of this unique mRNA 3′ end requires Stem-loop Binding Protein (SLBP), which directly binds histone pre-mRNA and stimulates 3′ end processing. The 3′ end stem-loop is necessary for all aspects of histone mRNA metabolism, including replication coupling, but its importance to organism fitness and genome maintenance in vivo have not been characterized.Methodology/Principal FindingsIn Drosophila, disruption of the Slbp gene prevents normal histone pre-mRNA processing and causes histone pre-mRNAs to utilize the canonical 3′ end processing pathway, resulting in polyadenylated histone mRNAs that are no longer properly regulated. Here we show that Slbp mutants display genomic instability, including loss of heterozygosity (LOH), increased presence of chromosome breaks, tetraploidy, and changes in position effect variegation (PEV). During imaginal disc growth, Slbp mutant cells show defects in S phase and proliferate more slowly than control cells.Conclusions/SignificanceThese data are consistent with a model in which changing the 3′ end of histone mRNA disrupts normal replication-coupled histone mRNA biosynthesis and alters chromatin assembly, resulting in genomic instability, inhibition of cell proliferation, and impaired development.
Canadian Gallup Poll # 300
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal elections vote intent(1); past federal elections vote(1); Canada as a nation(2); Canadian political leaders(9); US prestige in the world(2); threats to world peace(1); Medicare(3). Note: Demographics(12). Dropped: driving license; country of origin.
Semileptonic Decay of $Ξ_c \to Ξ\ell^+ ν_\ell$ From Light-Cone QCD Sum Rules
Creators: name: Duan, Hui-Hui
name: Liu, Yong-Lu
name: Huang, Ming-Qiu
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Semileptonic decay processes of $Ξ_c \to Ξ\ellν_\ell$ are studied by light-cone QCD sum rules in this paper. The six form factors of $Ξ_c \to Ξ$ semileptonic transition matrix elements are calculated by this method with the light-cone distribution amplitudes of $Ξ$ baryon up to twist six. With the six form factors, the absolute branching ratios of $Ξ_c^0 \to Ξ^- \ell^+ ν_\ell$ and $Ξ_c^+ \to Ξ^0 \ell^+ ν_\ell$ are calculated by the helicity amplitudes formalism of semileptonic differential decay widths. The ratios of absolute branching ratios of electron and muon final states processes give the proof of lepton flavor universality. Our results are in accordance with the recent experimental and theoretical reports.
description: 11 pages, 2 figures
Smoothness of generalized solutions for higher-order elliptic equations with nonlocal boundary conditions
Creators: name: Gurevich, Pavel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35J40, 35D10

description: Smoothness of generalized solutions for higher-order elliptic equations with nonlocal boundary conditions is studied in plane domains. Necessary and sufficient conditions upon the right-hand side of the problem and nonlocal operators under which the generalized solutions possess an appropriate smoothness are established.
description: 25 pages, 2 figures. arXiv admin note: substantial text overlap with arXiv:1404.5162
Low Enzymatic Activity Haplotypes of the Human Catechol-O-Methyltransferase Gene: Enrichment for Marker SNPs
Creators: name: Satterfield, Sarah K.
name: Diatchenko, Luda
name: Nackley, Andrea G.
name: Lambert, Jason E.
name: Conrad, Mathew S.
name: Gibson, Dustin G.
name: Shabalina, Svetlana A.
name: Spiridonov, Alexey N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol-dependent functions such as cognition, cardiovascular function, and pain processing. Three common haplotypes of the human COMT gene, divergent in two synonymous and one nonsynonymous (val158met) position, designated as low (LPS), average (APS), and high pain sensitive (HPS), are associated with experimental pain sensitivity and risk of developing chronic musculoskeletal pain conditions. APS and HPS haplotypes produce significant functional effects, coding for 3- and 20-fold reductions in COMT enzymatic activity, respectively. In the present study, we investigated whether additional minor single nucleotide polymorphisms (SNPs), accruing in 1 to 5% of the population, situated in the COMT transcript region contribute to haplotype-dependent enzymatic activity. Computer analysis of COMT ESTs showed that one synonymous minor SNP (rs769224) is linked to the APS haplotype and three minor SNPs (two synonymous: rs6267, rs740602 and one nonsynonymous: rs8192488) are linked to the HPS haplotype. Results from in silico and in vitro experiments revealed that inclusion of allelic variants of these minor SNPs in APS or HPS haplotypes did not modify COMT function at the level of mRNA folding, RNA transcription, protein translation, or enzymatic activity. These data suggest that neutral variants are carried with APS and HPS haplotypes, while the high activity LPS haplotype displays less linked variation. Thus, both minor synonymous and nonsynonymous SNPs in the coding region are markers of functional APS and HPS haplotypes rather than independent contributors to COMT activity.
Macroalgae Has No Effect on the Severity and Dynamics of Caribbean Yellow Band Disease
Creators: name: Harris, Sam
name: Bruno, John F.
name: Weil, Ernesto
name: Whitehead, Robert F.
name: Smelick, Gillian
name: Lee, Sarah C.
name: Vu, Ivana
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: By removing herbivores and promoting increases in macroalgae, overfishing is thought to indirectly cause coral disease and mortality. We performed three field manipulations to test the general hypothesis that overfishing and the subsequent alteration of coral reef trophic dynamics are a cause of coral epizootics. Specifically, we asked whether the presence of macroalgae can influence within- and among-colony spread rates of Caribbean Yellow Band Disease in Montastraea faveolata. Macroalgae were placed next to infected and healthy, adult and small coral colonies to measure effects on disease spread rate, coral growth and coral survival. Surprisingly, the addition of macroalgae did not affect disease severity or coral fitness. Our results indicate that macroalgae have no effect on the severity and dynamics of Caribbean Yellow Band Disease and that fisheries management alone will not mitigate the effects of this important epizootic.
Canadian Gallup Poll # 341
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); tax reform(18); influence of interest groups(6); birth control pills(3); Quebec's separatism(1); government's treatment of farmers(1); TV programs(2); old age pensions(1); unemployment(1). Note: Demographics(11).
Finite index subgroups without unique product in graphical small cancellation groups
Creators: name: Gruber, Dominik
name: Martin, Alexandre
name: Steenbock, Markus
Publisher: name: arXiv
Year: 2014
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20F06, 20F67

description: We construct torsion-free hyperbolic groups without unique product whose subgroups up to some given finite index are themselves non-unique product groups. This is achieved by generalising a construction of Comerford to graphical small cancellation presentations, showing that for every subgroup $H$ of a graphical small cancellation group there exists a free group $F$ such that $H*F$ admits a graphical small cancellation presentation.
description: 8 pages, 1 figure
Canadian Gallup Poll # 287
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); economic conditions(2); students' workload in public schools(6); equal job opportunities for married women(1); Prime Minister job performance(2); shorter work-week(2); image of the best political party(2); racial politics in South Africa(2); fluoridation of water(2); immigration to Canada(1). Note: Demographics(11).
Canadian Gallup Poll # 315
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Upcoming federal election: interest, vote intent, election campaign(6); current party preference(1); Canada-US relations(1); relations between English and French speaking Canadians(1); inflation(1); political parties and organized interests(5); economic conditions(2); job opportunities for married women(1); labor unions and employment(1). Note: Demographics(14).
Emergence of spinons in layered trimer iridate Ba4Ir3O10
Creators: name: Shen, Y.
name: Sears, J.
name: Fabbris, G.
name: Weichselbaum, A.
name: Yin, W.
name: Zhao, H.
name: Mazzone, D. G.
name: Miao, H.
name: Upton, M . H.
name: Casa, D.
name: Acevedo-Esteves, R.
name: Nelson, C.
name: Barbour, A. M.
name: Mazzoli, C.
name: Cao, G.
name: Dean, M. P. M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Spinons are well-known as the elementary excitations of one-dimensional antiferromagnetic chains, but means to realize spinons in higher dimensions is the subject of intense research. Here, we use resonant x-ray scattering to study the layered trimer iridate Ba4Ir3O10, which shows no magnetic order down to 0.2 K. An emergent one-dimensional spinon continuum is observed that can be well-described by XXZ spin-1/2 chains with magnetic exchange of ~55 meV and a small Ising-like anisotropy. With 2% isovalent Sr doping, magnetic order appears below TN=130 K along with sharper excitations, indicating that the spinons become more confined in (Ba1-xSrx)4Ir3O10. We propose that the frustrated intra-trimer interactions effectively reduce the system into decoupled spin chains, the subtle balance of which can be easily tipped by perturbations such as chemical doping. Our results put Ba4Ir3O10 between the one-dimensional chain and two-dimensional quantum spin liquid scenarios, illustrating a new way to suppress magnetic order and realize fractional spinons.
description: Accepted in Physical Review Letters; 5 pages not including references or supplementary
Canadian Gallup Poll # 361
Creators: name: Canadian Institute Of Public Opinion (Gallup)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Federal election vote intent(1); past federal elections vote(1); greatest problem facing Canada(2); rising food prices(4); federal government job performance(1); confidence in US(1); conversion to metric system of measurement(3); political parties electoral performance(3); rating foreign countries(4); conflict of interest and government workers(3); strikes(1); Canadian Confederation(2). Note: Demographics(10).
On Lattices, Learning with Errors, Random Linear Codes, and Cryptography
Creators: name: Regev, Oded
Publisher: name: arXiv
Year: 2024
Subjects: subject: Cryptography and Security (cs.CR)
subject: Computational Complexity (cs.CC)
subject: Quantum Physics (quant-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Our main result is a reduction from worst-case lattice problems such as GapSVP and SIVP to a certain learning problem. This learning problem is a natural extension of the `learning from parity with error' problem to higher moduli. It can also be viewed as the problem of decoding from a random linear code. This, we believe, gives a strong indication that these problems are hard. Our reduction, however, is quantum. Hence, an efficient solution to the learning problem implies a quantum algorithm for GapSVP and SIVP. A main open question is whether this reduction can be made classical (i.e., non-quantum).
 We also present a (classical) public-key cryptosystem whose security is based on the hardness of the learning problem. By the main result, its security is also based on the worst-case quantum hardness of GapSVP and SIVP. The new cryptosystem is much more efficient than previous lattice-based cryptosystems: the public key is of size $\tilde{O}(n^2)$ and encrypting a message increases its size by a factor of $\tilde{O}(n)$ (in previous cryptosystems these values are $\tilde{O}(n^4)$ and $\tilde{O}(n^2)$, respectively). In fact, under the assumption that all parties share a random bit string of length $\tilde{O}(n^2)$, the size of the public key can be reduced to $\tilde{O}(n)$.
description: Identical to the version posted in 2009, apart from fixing a bug in the proof of Claim 3.13
MAVS-Mediated Apoptosis and Its Inhibition by Viral Proteins
Creators: name: Liesman, Rachael M.
name: Ting, Jenny P.-Y.
name: Lei, Yu
name: Chen, Zhijian J.
name: Pickles, Raymond J.
name: O'Connor, Brian P.
name: Bergstralh, Daniel T.
name: Moore, Chris B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: BackgroundHost responses to viral infection include both immune activation and programmed cell death. The mitochondrial antiviral signaling adaptor, MAVS (IPS-1, VISA or Cardif) is critical for host defenses to viral infection by inducing type-1 interferons (IFN-I), however its role in virus-induced apoptotic responses has not been elucidated.Principal FindingsWe show that MAVS causes apoptosis independent of its function in initiating IFN-I production. MAVS-induced cell death requires mitochondrial localization, is caspase dependent, and displays hallmarks of apoptosis. Furthermore, MAVS−/− fibroblasts are resistant to Sendai virus-induced apoptosis. A functional screen identifies the hepatitis C virus NS3/4A and the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) nonstructural protein (NSP15) as inhibitors of MAVS-induced apoptosis, possibly as a method of immune evasion.SignificanceThis study describes a novel role for MAVS in controlling viral infections through the induction of apoptosis, and identifies viral proteins which inhibit this host response.
Designing quantum many-body matter with conditional generative adversarial networks
Creators: name: Koch, Rouven
name: Lado, Jose L.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The computation of dynamical correlators of quantum many-body systems represents an open critical challenge in condensed matter physics. While powerful methodologies have risen in recent years, covering the full parameter space remains unfeasible for most many-body systems with a complex configuration space. Here we demonstrate that conditional Generative Adversarial Networks (GANs) allow simulating the full parameter space of several many-body systems, accounting both for controlled parameters, and stochastic disorder effects. After training with a restricted set of noisy many-body calculations, the conditional GAN algorithm provides the whole dynamical excitation spectra for a Hamiltonian instantly and with an accuracy analogous to the exact calculation. We further demonstrate how the trained conditional GAN automatically provides a powerful method for Hamiltonian learning from its dynamical excitations, and to flag non-physical systems via outlier detection. Our methodology puts forward generative adversarial learning as a powerful technique to explore complex many-body phenomena, providing a starting point to design large-scale quantum many-body matter.
Olfactory Sex Recognition Investigated in Antarctic Prions
Creators: name: Bonadonna, Francesco
name: Brooke, M. de L.
name: Caro, Samuel P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Chemical signals can yield information about an animal such as its identity, social status or sex. Such signals have rarely been considered in birds, but recent results have shown that chemical signals are actually used by different bird species to find food and to recognize their home and nest. This is particularly true in petrels whose olfactory anatomy is among the most developed in birds. Recently, we have demonstrated that Antarctic prions, Pachyptila desolata, are also able to recognize and follow the odour of their partner in a Y-maze.
Statistical modelling of COVID-19 data: Putting Generalised Additive Models to work
Creators: name: Fritz, Cornelius
name: De Nicola, Giacomo
name: Rave, Martje
name: Weigert, Maximilian
name: Khazaei, Yeganeh
name: Berger, Ursula
name: Küchenhoff, Helmut
name: Kauermann, Göran
Publisher: name: arXiv
Year: 2022
Subjects: subject: Applications (stat.AP)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Over the course of the COVID-19 pandemic, Generalised Additive Models (GAMs) have been successfully employed on numerous occasions to obtain vital data-driven insights. In this paper we further substantiate the success story of GAMs, demonstrating their flexibility by focusing on three relevant pandemic-related issues. First, we examine the interdepency among infections in different age groups, concentrating on school children. In this context, we derive the setting under which parameter estimates are independent of the (unknown) case-detection ratio, which plays an important role in COVID-19 surveillance data. Second, we model the incidence of hospitalisations, for which data is only available with a temporal delay. We illustrate how correcting for this reporting delay through a nowcasting procedure can be naturally incorporated into the GAM framework as an offset term. Third, we propose a multinomial model for the weekly occupancy of intensive care units (ICU), where we distinguish between the number of COVID-19 patients, other patients and vacant beds. With these three examples, we aim to showcase the practical and "off-the-shelf" applicability of GAMs to gain new insights from real-world data.
Resonant thermal Hall effect of phonons coupled to dynamical defects
Creators: name: Guo, Haoyu
name: Joshi, Darshan G.
name: Sachdev, Subir
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present computations of the thermal Hall coefficient of phonons scattering off a defect with multiple energy levels. Using a microscopic formulation based on the Kubo formula, we find that the leading contribution perturbative in the phonon-defect coupling is proportional to the phonon lifetime, and has a `side-jump' interpretation. Consequently, the thermal Hall angle is independent of the phonon lifetime. The contribution to the thermal Hall coefficient is at resonance when the phonon energy equals a defect level spacing. Our results are obtained for three different defect models, which apply to different correlated electron materials. For the pseudogap regime of the cuprates, we propose a model of phonons coupled to an impurity quantum spin in the presence of quasi-static magnetic order with an isotropic Zeeman coupling to the applied field, and without spin-orbit interaction.
description: 7 pages, 3 figures
Cosmic Strings in Hidden Sectors: 2. Cosmological and Astrophysical Signatures
Creators: name: Long, Andrew J.
name: Vachaspati, Tanmay
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Cosmic strings can arise in hidden sector models with a spontaneously broken Abelian symmetry group. We have studied the couplings of the Standard Model fields to these so-called dark strings in the companion paper. Here we survey the cosmological and astrophysical observables that could be associated with the presence of dark strings in our universe with an emphasis on low-scale models, perhaps TeV. Specifically, we consider constraints from nucleosynthesis and CMB spectral distortions, and we calculate the predicted fluxes of diffuse gamma ray cascade photons and cosmic rays. For strings as light as TeV, we find that the predicted level of these signatures is well below the sensitivity of the current experiments, and therefore low scale cosmic strings in hidden sectors remain unconstrained. Heavier strings with a mass scale in the range 10^(13) GeV to 10^(15) GeV are at tension with nucleosynthesis constraints.
description: 32 pages, 7 figures
Positive Reciprocal Regulation of Ubiquitin C-Terminal Hydrolase L1 and β-Catenin/TCF Signaling
Creators: name: Whitehurst, Chris
name: Shackelford, Julia
name: Gullapalli, Anuradha
name: Pagano, Joseph S.
name: Bheda, Anjali
name: Liu, Renshui
name: Yue, Wei
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Deubiquitinating enzymes (DUBs) are involved in the regulation of distinct critical cellular processes. Ubiquitin C-terminal Hydrolase L1 (UCH L1) has been linked to several neurological diseases as well as human cancer, but the physiological targets and the regulation of UCH L1 expression in vivo have been largely unexplored. Here we demonstrate that UCH L1 up-regulates β-catenin/TCF signaling: UCH L1 forms endogenous complexes with β-catenin, stabilizes it and up-regulates β-catenin/TCF-dependent transcription. We also show that, reciprocally, β-catenin/TCF signaling up-regulates expression of endogenous UCH L1 mRNA and protein. Moreover, using ChIP assay and direct mutagenesis we identify two TCF4-binding sites on the uch l1 promoter that are involved in this regulation. Since the expression and deubiquitinating activity of UCH L1 are required for its own basic promoter activity, we propose that UCH L1 up-regulates its expression by activation of the oncogenic β-catenin/TCF signaling in transformed cells.
Sparse Distributed Learning via Heterogeneous Diffusion Adaptive Networks
Creators: name: Das, Bijit Kumar
name: Chakraborty, Mrityunjoy
name: Arenas-García, Jerónimo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Machine Learning (cs.LG)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Systems and Control (eess.SY)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In-network distributed estimation of sparse parameter vectors via diffusion LMS strategies has been studied and investigated in recent years. In all the existing works, some convex regularization approach has been used at each node of the network in order to achieve an overall network performance superior to that of the simple diffusion LMS, albeit at the cost of increased computational overhead. In this paper, we provide analytical as well as experimental results which show that the convex regularization can be selectively applied only to some chosen nodes keeping rest of the nodes sparsity agnostic, while still enjoying the same optimum behavior as can be realized by deploying the convex regularization at all the nodes. Due to the incorporation of unregularized learning at a subset of nodes, less computational cost is needed in the proposed approach. We also provide a guideline for selection of the sparsity aware nodes and a closed form expression for the optimum regularization parameter.
description: 4 pages, 1 figure, conference, submitted to IEEE ISCAS 2015, Lisbon, Portugal
Work-Life Balance Among Private Hospital Nurses – A Study In Mysuru City
Creators: name: Naveen Kumar M S
name: Pooja K
Publisher: name: Zenodo
Year: 2018

description: Working in the health care sector is distinctive compared to other industries. Nurses working in hospitalsplay a vital role to maintain the health-status of patients. Nursing is the protection, promotion and optimization ofhealth centers. In nursing, the health requirement of others is paramount instead of their own, in this case, a womanmay find trouble in managing work-life balance. The health workers come across multiple challenges like heavyworkloads, overtime, irregular shifts, physical and psychological stress which increases the risk of burnouts anddepression. The current paper focuses on work-life balance dilemmas faced by nurses working in private hospitalsand suggestions to the hospital management to implement effective and feasible working conditions to overcome theissues. They must introduce work-life balance policies to provide formal support at the workplace and optimizenursing for the wellbeing of nurses, their family and also patients. This paper figures out data from nurses that theydon’t have enough time to spend with their family and various other reasons which finally create stress and issue ofwork-life balance.