cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
PROCESS INTENSIFICATION OF INTEGRATED CONTINUOUS CRYSTALLIZATION SYSTEMS WITH RECYCLE
Creators: name: Parvaresh, Rozhin Rojan
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 400409
subject: Separation technologies
classificationCode: 400407
subject: Process control and simulation
classificationCode: 400406
subject: Powder and particle technology

description: The purification of most active pharmaceutical ingredients (APIs) is primarily achieved through crystallization, conducted in batch, semi-batch, or continuous modes. Recently, continuous crystallization has gained interest in the pharmaceutical industry for its potential to reduce manufacturing costs and maintenance. Crystal characteristics such as size, purity, and polymorphism significantly affect downstream processes like filtration and tableting, as well as physicochemical properties like bioavailability, flowability, and compressibility. Developing an optimal operation that meets the critical quality attributes (CQAs) of these crystal properties is essential.This dissertation begins by focusing on designing an innovative integrated crystallization system to enhance control over crystalline material properties. The system expands the attainable region of crystal size distribution (CSD) by incorporating multiple Mixed-Suspension Mixed-Product Removal (MSMPR) units and integrating wet milling, classification, and a recycle loop, enhancing robustness and performance. Extensive simulations and experimental data validate the framework, demonstrating significant improvements in efficiency and quality. The framework is further generalized to optimize crystallizer networks for controlling critical quality attributes such as mean size, yield, and CSD by evaluating various network configurations to identify optimal operating parameters.The final part of this work concentrates on using the framework to improve continuous production of a commercial API, Atorvastatin calcium (ASC), aiming for higher yield and lower costs. This approach establishes an attainable region to increase crystal sizes and productivity. Due to ASC’s nucleation-dominated nature, the multi-stage system could not grow the crystals sufficiently to bypass granulation, the bottleneck process in ASC manufacturing. Therefore, spherical agglomeration was proposed as an intensification process within an integrated two-stage crystallization spherical agglomeration system to control the size and morphology of ASC crystals and improve downstream processing and tableting. This method proved highly successful, leading to the development of an end-to-end continuous manufacturing process integrating reaction, crystallization, spherical agglomeration, filtration, and drying. This modular system effectively addressed challenges in integrating various unit operations into a coherent continuous process with high production rates.
Bundestagswahl und Web 2.0 - wie verändert sich Politik durch Social Media?
Creators: name: Templ, Karl Ulrich
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Web 2.0
subject: DDC 320 / Political science
subject: Online social networks
subject: Social media
subject: Politik
subject: Soziales Netzwerk
subject: World Wide Web 2.0

description: Karl Ulrich Templ ist stellvertretender Direktor der Landeszentrale für Politische Bildung Baden-Württemberg und gleichzeitig Verantwortlicher für den Bereich "Neue Medien". In diesem Vortrag stellt er Untersuchungen und Beobachtungen vor, welche die Rolle der sozialen Netzwerke für die Bundestagswahlen 2013 betreffen. Der Vortrag fand am 26. November 2013 als Veranstaltung des AK Media beim Zentrum für Allgemeine Wissenschaftliche Weiterbildung (ZAWiW) der Universität Ulm statt.
Additional file 1 of KAKU4 regulates leaf senescence through modulation of H3K27me3 deposition in the Arabidopsis genome
Creators: name: Cao, Yaxin
name: Yan, Hengyu
name: Sheng, Minghao
name: Liu, Yue
name: Yu, Xinyue
name: Li, Zhongqiu
name: Xu, Wenying
name: Su, Zhen
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1
الإشكالات العملية في تنفيذ الأحكام القضائية
Creators: name: محمد مومن وعزالدين الماحي
Publisher: name: Zenodo
Year: 2024

description: يتناول هذا العدد الخاص من مجلة محاكمة أشغال الندوة العلمية الوطنية في موضوع الإشكالات العملية في تنفيذ الأحكام القضائية التي نظمها يوم 11 نونبر 2023 مختبر الدراسات القانونية المدنية والعقارية ومجموعة من خريجي كلية العلوم القانونية والاقتصادية والاجتماعية بمراكش
sj-pdf-1-trr-10.1177_03611981231179703 – Supplemental material for Traffic Flow as a Simple Fluid: Toward a Scaling Theory of Urban Congestion
Creators: name: Laval, Jorge A.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Urban and Regional Planning not elsewhere classified

description: Supplemental material, sj-pdf-1-trr-10.1177_03611981231179703 for Traffic Flow as a Simple Fluid: Toward a Scaling Theory of Urban Congestion by Jorge A. Laval in Transportation Research Record
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 230 (29. Jg.), Juni 1999
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: Universities; Germany; Ulm
subject: Ulm / Universität

description: N/A
Additional file 5 of KAKU4 regulates leaf senescence through modulation of H3K27me3 deposition in the Arabidopsis genome
Creators: name: Cao, Yaxin
name: Yan, Hengyu
name: Sheng, Minghao
name: Liu, Yue
name: Yu, Xinyue
name: Li, Zhongqiu
name: Xu, Wenying
name: Su, Zhen
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 5
Identifying relationships between multi-scale social-ecological factors to explore ungulate health in a Western Kazakhstan rangeland
Creators: name: Khanyari, Munib
name: Robinson, Sarah
name: Morgan, Eric
name: Salemgareyev, Albert
name: Milner-Gulland, E.J.
Publisher: name: Zenodo
Year: 2021

description: 1. Rangelands are multi-use landscapes which are socially and ecologically important in different ways. Among other interactions, shared use of rangelands by wildlife and livestock can lead to disease transmission. Understanding wildlife and livestock health and managing disease transmission in rangelands requires an integration of social and ecological knowledge. 2. Using the example of Western Kazakhstan, home to two types of ungulate hosts, the critically-endangered saiga antelopes, Saiga tatarica, and livestock, we conducted a cross-scale analysis of social-economic, ecological and climatic factors that contribute to transmission of diseases. We focused on Gastro-intestinal Nematodes (GINs) because they are transmitted between hosts that share pasture and they affect ungulate fitness. We used an interdisciplinary social-ecological methods approach which included conducting fecal egg counts of GINs in saigas and livestock, semi-structured interviews and focus group discussions with livestock owners and herders in the region, and triangulation of information through secondary sources. 3. Livestock rearing was done in two ways a) village-based livestock and b) outlying farms. The latter overlapped more with saigas. Village-based livestock had significantly higher worm burdens than those on outlying farms, which had comparable burdens to saigas. Various factors exacerbate GIN prevalence and transmission: Veterinary services are minimal; both saiga and livestock numbers are increasing; and changing climate is increasing farmers' dependence on shared pastures for hay production. It will be crucial for saiga conservationists to engage in multi-pronged conservation interventions, which are evaluated and adapted through the lens of rural livelihoods and the livestock health on which they depend. 4. Synthesis and Application: Our work provides researchers and practitioners with an avenue to better understand complex inter-relationships and plan interventions within rangelands, while viewing host health from an interdisciplinary perspective - ultimately working towards wildlife conservation whilst safeguarding livelihoods across the world's rangelands.
On span-Pcc and related classes in structural communication complexity
Creators: name: Wunderlich, Henning
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: #P
subject: Communication complexity
subject: max-P
subject: min-P
subject: opt-P
subject: span-P
subject: DDC 004 / Data processing & computer science
subject: Computational complexity
subject: Komplexitätsklasse
subject: Komplexitätstheorie

description: The complexity classes #P, #NP, min-P, max-P, opt-P and span-P are well known in structural complexity. We define analogous classes in (structural) communication complexity and study some of their properties, e.g. establishing the inclusions #P \subseteq span-P, span-P \subseteq #NP and max-P \subseteq span-P. Especially, in contrast to the current state of affairs in time complexity, we are able to prove the following separations: 1. #P \subsetneq span-P \subsetneq #NP 2. max-P \not\subseteq #P, max-P \subsetneq span-P 3. min-P \neq max-P, min-P \not\subseteq span-P.
Supplemental Material - When do leaders feel stressed by their followers? An examination of face-to-face, virtual and written interactions
Creators: name: Gesang, Elena
name: Klingenberg, Ingo
name: Süß, Stefan
Publisher: name: SAGE Journals
Year: 2023
Subjects: Organisation and Management Theory

description: Supplemental Material for When do leaders feel stressed by their followers? An examination of face-to-face, virtual and written interactions by Elena Gesang, Ingo Klingenberg, and Stefan Süß in Leadership.
Exploring the Clinical Relevance of p31comet in Head and Neck Squamous Cell Carcinoma through UALCAN database analysis
Creators: name: Henriques, Ana C. Henriques
name: Silva, João P. N.
name: Pinto, Bárbara
name: Silva, Patricia M. A.
name: Bousbaa, Hassan
Publisher: name: Scientific Letters
Year: 2024

description: The p31comet protein plays a pivotal role in regulating spindle assembly checkpoint silencing and is overexpressed in several cancers, including oral cancer. Despite this, its exact roles in tumorigenesis and its prognostic significance remain unclear. In this study, using the UALCAN cancer database, we analyzed p31comet expression and its correlation with clinical indicators in Head and Neck Squamous Cell Carcinoma (HNSCC). Our findings revealed a significant upregulation of p31comet in HNSCC patients. Interestingly, we observed a positive correlation between p31comet expression and known interactors such as MAD2L1 and TRIP13, as well as regulators of p31comet expression. Furthermore, we found that p31comet expression was notably increased in tumor samples exhibiting alterations in the mTOR pathway and the SWI/SNF chromatin remodeling complexes. Intriguingly, HNSCC patients with high p31comet expression showed a tendency towards better prognosis compared to those with low/medium expression levels. This tendency did not reach statistical significance, likely due to variations in patient cohort sizes within the database. In summary, our findings suggest that increased p31comet expression could be a potential marker for tumor occurrence and metastasis in HNSCC patients, opening avenues for further research to understand its prognostic significance.
description: Scientific Letters, Vol. 1 No. 1 (2024)
Depressive disorder with panic attacks after replacement of an intrauterine device containing levonorgestrel: a case report
Creators: name: Zeiss, René
name: Schönfeldt-Lecuona, Carlos
name: Gahr, Maximilian
name: Graf, Heiko
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: DDC 610 / Medicine & health
subject: Contraception
subject: Intrauterine devices
subject: Levonorgestrel
subject: Depression
subject: Anxiety
subject: Empfängnisverhütungsmittel
subject: Intrauterinpessar
subject: Arzneimittelnebenwirkung

description: The levonorgestrel-releasing intrauterine system (LNG-IUS) is used as hormonal contraception by millions of women worldwide. It is considered as a safe device with low rates of systemic adverse drug reactions (ADRs). However, an emerging evidence suggest mood changes as ADRs. Whereas most of these studies report psychiatric ADRs after the first implantation of the LNG-IUS, it has to be considered that these may also occur after replacement, even when psychiatric symptoms were not evident at the time of the initial insertion. A potential explanation for the development of psychiatric ADRs in subsequent LNG-IUS may rely on fluctuations of sex hormones throughout the female life cycle with changing windows of vulnerabilities for developing mood disorders. Thus, the reliable contraception for women remains a continual challenge. We present the case of a 41-year-old woman that used the LNG-IUS (Mirena®) for contraception over 5 years without any complaints. Within the first weeks after insertion of the second LNG-IUS, she developed a depressive syndrome and anxieties. An extensive somatic, including gynecological examination revealed no pathological findings and a mental disorder was suggested. Due to the patient´s request and the recommendation of her psychiatrist, the device was removed and led to a remission of her mental complaints up to a 6- and 12-months follow-up. Beyond the mood changes considerably affecting her quality of life, the patient raised the concerns that she has never been informed about potential ADRs on mental health and her remarks regarding the potential association between psychiatric symptoms and the LNG-IUS were considered as groundless. With this case, we strengthen previous observations regarding mood changes under LNG-IUS. Moreover, we illustrate that psychiatric symptoms may also occur as ADRs during the subsequent insertion. Thus, we emphasize that psychiatric symptoms have to be clearly communicated as ADRs to patients with LNG-IUS within a written informed consent and should be routinely examined by gynecologists.
Soziokulturelle Animation Und Bildungsförderung In Benin: Ein Beitrag Der Soziokulturellen Animation Zur Informellen Bildungsförderung Der Kinder Im Primarschulalter In Benin
Creators: name: Logovi, Isabelle
Publisher: name: Zenodo
Year: 2011
Subjects: subject: gnd:4721392-9
subject: gnd:4005503-6

description: Diese Bachelor-Arbeit zeigt Handlungsmöglichkeiten für die Soziokulturelle Animation (SKA) im informellen Bildungssektor Benins auf. Benin ist eines der kleinsten Länder Afrikas und gleichzeitig eines der ärmsten der Welt. Das Bildungsniveau wird in engen Zusammenhang mit dem Lebensstandard der Menschen gebracht. Bildung wird als besonders wirksame Methode angesehen, um langfristig Armut zu bekämpfen. Die Bildungsgeschichte Benins ist turbulent und hat ihre Spuren hinterlassen. So weist das heutige Bildungssystem eine Vielzahl an Herausforderungen auf. Die beninische Zivilgesellschaft lebt zwischen alten und neuen Bildungssystemen. Formelle, informelle und traditionelle Bildungsformen agieren parallel zueinander. Dies birgt Hürden für die nationale Entwicklung Benins, wobei Kinder häufig die Leidtragenden sind. Die beninische Regierung hat den Ernst der Lage seiner Bildungssituation erkannt und setzt sich für deren Verbesserung ein. Durch nationale Abkommen hat sie Rahmenbedingungen geschaffen, um die Situation zu verbessern. Zudem engagieren sich nationale und internationale Nichtregierungsorganisationen seit Jahrzehnten, um Fortschritte im Bildungssektor zu erzielen. Benin kann dank grossem Einsatz durchaus Verbesserungen im Bildungsbereich verzeichnen. Trotzdem bleiben – bis alle Kinder im Primarschulalter eine Grundschulbildung erhalten – viele Herausforderungen des Bildungsbereichs aktuell und verlangen nach dringender Bearbeitung. Welche das sind und welche Rolle die Soziokulturelle Animation (SKA) bei der Bildungsförderung einnehmen kann – diesen Fragen geht die vorliegende Bachelor-Arbeit nach und geht darauf ein, inwiefern die Methoden der SKA adäquate Lösungsansätze für den informellen Bildungssektor darstellen kann. Dabei liegt der Fokus auf Kindern im Primarschulalter in Benin.
description: + Code Diss LU: hslusa bask 2011 + Fussnote: Bachelor-Arbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Soziokultur 2011
Diversification of Crassula: Phylogenetic analysis and life-form traits
Creators: name: Fradera-Soler, Marc
name: Lu, Meng
name: Grace, Olwen M.
Publisher: name: Zenodo
Year: 2022

description: These datasets are associated with the published paper - "Evidence linking life form to a major shift in diversification rate in Crassula" (DOI:10.1002/ajb2.1797) Crassula L. (Crassulaceae) is a characteristic element of the southern African flora, occurring in a wide range of habitats, and it exhibits a remarkable diversity of life forms. However, whether any particular life-form trait has shaped species diversification in Crassula has remained unexplored. Our study aimed to investigate diversification patterns within Crassula and identify potential links to its life-form evolution. A phylogenetic tree of 140 Crassula taxa was reconstructed using plastid and nuclear loci, and dated based on the nuclear DNA information only. We reconstructed ancestral life-form characters to estimate the evolutionary trends of ecophysiological change, and subsequently estimated net diversification rates. The datasets presented here summarise the life-form classification (incl. life-history strategies and growth forms) of all Crassula species and the data from our phylogenetic analysis.
sj-docx-1-tan-10.1177_17562864231213240 – Supplemental material for Guideline for the management of myasthenic syndromes
Creators: name: Wiendl, Heinz
name: Abicht, Angela
name: Chan, Andrew
name: Della Marina, Adela
name: Hagenacker, Tim
name: Hekmat, Khosro
name: Hoffmann, Sarah
name: Hoffmann, Hans-Stefan
name: Jander, Sebastian
name: Keller, Christian
name: Marx, Alexander
name: Melms, Arthur
name: Melzer, Nico
name: Müller-Felber, Wolfgang
name: Pawlitzki, Marc
name: Rückert, Jens-Carsten
name: Schneider-Gold, Christiane
name: Schoser, Benedikt
name: Schreiner, Bettina
name: Schroeter, Michael
name: Schubert, Bettina
name: Sieb, Jörn-Peter
name: Zimprich, Fritz
name: Meisel, Andreas
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-tan-10.1177_17562864231213240 for Guideline for the management of myasthenic syndromes by Heinz Wiendl, Angela Abicht, Andrew Chan, Adela Della Marina, Tim Hagenacker, Khosro Hekmat, Sarah Hoffmann, Hans-Stefan Hoffmann, Sebastian Jander, Christian Keller, Alexander Marx, Arthur Melms, Nico Melzer, Wolfgang Müller-Felber, Marc Pawlitzki, Jens-Carsten Rückert, Christiane Schneider-Gold, Benedikt Schoser, Bettina Schreiner, Michael Schroeter, Bettina Schubert, Jörn-Peter Sieb, Fritz Zimprich and Andreas Meisel in Therapeutic Advances in Neurological Disorders
Additional file 8 of KAKU4 regulates leaf senescence through modulation of H3K27me3 deposition in the Arabidopsis genome
Creators: name: Cao, Yaxin
name: Yan, Hengyu
name: Sheng, Minghao
name: Liu, Yue
name: Yu, Xinyue
name: Li, Zhongqiu
name: Xu, Wenying
name: Su, Zhen
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 8
title: "Ein Spiel für drei" - chinesische Studierende in Österreich
Creators: name: Chen, Chun Meng
Year: 2009

description: In dieser Arbeit geht es um das Spiel der Beziehung zwischen den chinesischen Studenten im Ausland, dem Herkunftsland (China) und dem Zielland. In der Entwicklung der Auslandsstudiengeschichte Chinas, haben und hatten das Land und das Individuum eignes Interesse, woher eine Frage kommt zu diskutieren – haben die Länder einen Einfluss auf das Auslandsstudium des Individuums, und wie groß wird der Einfluss sein? Analysiert man die Auslandsstudienpolitik aus dem Herkunftsland und den Zielländern, erkennt man, dass die Interaktion zwischen Ländern entweder aktiv, unsymmetrisch oder passiv verläuft. Das beeinflusst die Verteilung der Zielländer und resultiert in einem Wettbewerb um Talente zwischen Ländern wie „Brain Drain“ und „Brain Gain“. Es gibt eher ein als „Brain in vain“ genanntes Phänomen unter chinesischen selbst finanzierten Studenten in Österreich. Sowohl Länder, die aus ihrem Interesse heraus ein Auslandsstudium unterstützen, als auch Individuen, die sich auf dem Auslandsstudienstrom werfen, sollten dieses Phänomen berücksichtigen.
description: This thesis is to study the game of the relationship among Chinese students abroad, homeland (China) and target-lands. In the development of the Chinese studying abroad history, the country and the individual had and have their own will and interest, which arouses the question to discuss – Do countries have an influence on the individual’s studying abroad, and how big will the influence be? Reading through the studying abroad policy from the homeland and the target-lands, we find the interaction between the country and the individual either active or insymmetric or passive. This affects the distribution of the target-lands and result in the competition for talents among countries like “brain drain” and “brain gain”. There is even one phenomenon called “brain in vain” among the Chinese self-financed students in Austria. When countries promote the studying abroad for the sake of their interest and individuals throw themselves into the studying abroad stream, both should be aware of that phenomenon.
Evaluation of the themes chosen for the dissertation of the Integrated Master’s Degree of the Children’s Oral Health and Prevention Service, at IUCS-CESPU
Creators: name: Azevedo, Mariana
name: Ferreira, Maria João
name: Cantante, Juliana
name: Oliveira, Ana Catarina
name: Lobo, Ana Paula
name: Sousa-Santos, Primavera
name: Vale, Teresa
Publisher: name: Scientific Letters
Year: 2024

description: The Children’s Oral Health and Prevention Service at IUCS-CESPU comprises three areas – Pediatric Dentistry, Orthodontics and Preventive Dentistry –, which, in the final years of the Integrated Master’s Degree in Dental Medicine, are taught within the scope of a single subject, the Pediatric Dentistry Clinic. Many of the topics covered here have stagnated due to a lack of knowledge, making it essential to recognize which areas are less popular, to captivate the interest of the students and fill these gaps. This study aimed to assess which topics in this service have more interest from dental students for their dissertations over the past eleven years. To do this, we collected all the dissertations between 2013-2023 in the Scientific Repository from the abovementioned service. Our study revealed a dominance of Orthodontics, followed by Preventive Dentistry and Psychology and Behavior Control. On the other hand, Pulpar Therapy, Diagnosis and Growth and Development are areas of little focus to students. We concluded that Orthodontics has always been the area of choice, while Preventive Dentistry, ranking second, has been in constant decline since 2015, as have Cariology and Conservative Treatments. Evaluating these choices allows us to better target teaching and meet the needs of the population.
description: Scientific Letters, Vol. 1 No. 1 (2024)
Non-additive dissipation in open quantum networks out of equilibrium
Creators: name: Mitchison, Mark T
name: Plenio, Martin B
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: open quantum systems
subject: master equation
subject: quantum transport
subject: non-Markovianity
subject: DDC 530 / Physics
subject: Dynamics
subject: Dynamik

description: Abstract We theoretically study a simple non-equilibrium quantum network whose dynamics can be expressed and exactly solved in terms of a time-local master equation. Specifically, we consider a pair of coupled fermionic modes, each one locally exchanging energy and particles with an independent, macroscopic thermal reservoir. We show that the generator of the asymptotic master equation is not additive, i.e. it cannot be expressed as a sum of contributions describing the action of each reservoir alone. Instead, we identify an additional interference term that generates coherences in the energy eigenbasis, associated with the current of conserved particles flowing in the steady state. Notably, non-additivity arises even for wide-band reservoirs coupled arbitrarily weakly to the system. Our results shed light on the non-trivial interplay between multiple thermal noise sources in modular open quantum systems.
Pacific Reef Assessment and Monitoring Program Fish Monitoring Brief: Jarvis Island, Palmyra Atoll, and Kingman Reef 2018
Creators: name: Coral Reef Conservation Program (U.S.)
name: National Marine Fisheries Service (U.S.)
name: Pacific Islands Fisheries Science Center (U.S.)
Publisher: name: National Marine Fisheries Service (U.S.)
Year: 2018

description: PIFSC Data Report DR-18-013
sj-docx-3-ltr-10.1177_13621688221127643 – Supplemental material for The effects of direct written corrective feedback and comparator texts on the complexity and accuracy of revisions and new pieces of writing
Creators: name: Hamano-Bunce, Douglas
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Education
subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: Supplemental material, sj-docx-3-ltr-10.1177_13621688221127643 for The effects of direct written corrective feedback and comparator texts on the complexity and accuracy of revisions and new pieces of writing by Douglas Hamano-Bunce in Language Teaching Research
Understanding the Psychological and Social Origins of Gender Disparities in Self-Beliefs, Motivation, and Educational Attainment
Creators: name: Van Zanden, Brooke
Publisher: name: Australian Catholic University
Year: 2018

description: The second wave feminist movement during the mid to late 20th century saw rapid advancements in contraceptive, legal, and economic rights of women. However, despite recent advances in women’s liberation, gender differences in educational outcomes (e.g., self-beliefs, attitudes, aspirations and educational attainment in science, technology, engineering and mathematics [STEM]) remain heavily entrenched. This thesis explores the notion that the gender gap in STEM has its origins in self-beliefs and task values of young people. However, less is known about how much of the STEM gender gap can be explained by these Expectancy Value Theory constructs. Moreover, there is a lack of research that utilises an intersectional lens to explore how social and cultural context moderates the size of gender gaps in self-beliefs and attitudes towards math and science. This thesis addresses these research gaps utilising meta-analytic, longitudinal, and interview data. Meta-analytic findings from 176 studies in Study 1 show that gender differences in expectancy value constructs are domain specific, and that there are significant moderation effects across social class, gender equality, and gender segregation in university enrollments. Study 2 explores the replicability of meta-analysis results from Study 1, and extends upon these results through an analysis of a large nationally representative database (n = 10,370) that includes ethnicity, geography, and educational attainment. Using the same database, results from Study 3 show that while EVT can account for some of the gender disparity in STEM enrollment, there is still a very large amount of difference that remains unexplained by current theory. Furthermore, results indicate that even when comparing male and female students of equal ability and attitudes, young women still are significantly disadvantaged in terms of STEM university enrollment. A content analysis in Study 4 explored whether open-ended interview data from young Australians who enrolled in a university STEM course (n = 447) versus those who chose to discontinue their STEM education after senior high school (n = 949) can add to current theory. Results point the role of dimensional comparison as critical to educational choices, but again, there were no major themes that arose that significantly deviate from current theory. Results are discussed in light of future directions for research, and implications for policymakers and educators.
sj-docx-4-ltr-10.1177_13621688221127643 – Supplemental material for The effects of direct written corrective feedback and comparator texts on the complexity and accuracy of revisions and new pieces of writing
Creators: name: Hamano-Bunce, Douglas
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Education
subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: Supplemental material, sj-docx-4-ltr-10.1177_13621688221127643 for The effects of direct written corrective feedback and comparator texts on the complexity and accuracy of revisions and new pieces of writing by Douglas Hamano-Bunce in Language Teaching Research
sj-docx-5-ltr-10.1177_13621688221127643 – Supplemental material for The effects of direct written corrective feedback and comparator texts on the complexity and accuracy of revisions and new pieces of writing
Creators: name: Hamano-Bunce, Douglas
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Education
subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: Supplemental material, sj-docx-5-ltr-10.1177_13621688221127643 for The effects of direct written corrective feedback and comparator texts on the complexity and accuracy of revisions and new pieces of writing by Douglas Hamano-Bunce in Language Teaching Research
Additional file 11 of KAKU4 regulates leaf senescence through modulation of H3K27me3 deposition in the Arabidopsis genome
Creators: name: Cao, Yaxin
name: Yan, Hengyu
name: Sheng, Minghao
name: Liu, Yue
name: Yu, Xinyue
name: Li, Zhongqiu
name: Xu, Wenying
name: Su, Zhen
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 11
DNA methylation profiles of bronchoscopic biopsies for the diagnosis of lung cancer
Creators: name: Goldmann, Torsten
name: Schmitt, Bernhard
name: Müller, Julia
name: Kröger, Maren
name: Scheufele, Swetlana
name: Marwitz, Sebastian
name: Nitschkowski, Dörte
name: Schneider, Marc
name: Meister, Michael
name: Muley, Thomas
name: Thomas, Michael
name: Kugler, Christian
name: Rabe, Klaus F.
name: Siebert, Reiner
name: Reck, Martin
name: Ammerpohl, Ole
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Lung cancer
subject: Paired biopsies
subject: DDC 610 / Medicine & health
subject: Lung neoplasms
subject: DNA methylation
subject: Biopsy
subject: Lungenkrebs
subject: Biopsie

description: Background: Lung cancer is the leading cause of cancer-related death in most western countries in both, males and females, accounting for roughly 20–25% of all cancer deaths. For choosing the most appropriate therapy regimen a definite diagnosis is a prerequisite. However, histological characterization of bronchoscopic biopsies particularly with low tumor cell content is often challenging. Therefore, this study aims at (a) determining the value of DNA methylation analysis applied to specimens obtained by bronchoscopic biopsy for the diagnosis of lung cancer and (b) at comparing aberrantly CpG loci identified in bronchoscopic biopsy with those identified by analyzing surgical specimens. Results: We report the HumanMethylation450-based DNA methylation analysis of paired samples of bronchoscopic biopsy specimens either from the tumor side or from the contralateral tumor-free bronchus in 37 patients with definite lung cancer diagnosis and 18 patients with suspicious diagnosis. A differential DNA methylation analysis between both biopsy sites of patients with definite diagnosis identified 1303 loci. Even those samples were separated by the set of 1303 loci in which histopathological analysis could not unambiguously define the dignity. Further differential DNA methylation analyses distinguished between SCLC and NSCLC. We validated our results in an independent cohort of 40 primary lung cancers obtained by open surgical resection and their corresponding controls from the same patient as well as in publically available DNA methylation data from a TCGA cohort which could also be classified with high accuracy. Conclusions: Considering that the prognosis correlates with tumor stage at time of diagnosis, early detection of lung cancer is vital and DNA methylation analysis might add valuable information to reliably characterize lung cancer even in histologically ambiguous sample material.
title: Einfluss von Supplementen auf den Status ausgewählter Vitamine und Mineralstoffe burgenländischer Senioren
Creators: name: Brandtner, Anna
Year: 2009

description: Der Einfluss einer regelmäßigen Supplementation auf den Status ausgewählter Vitamine und Mineralstoffe burgenländischer Senioren ab dem 70. Lebenjahr. Zur Beurteilung wurden sowohl laborchemische Daten in Plasma, Harn und Erythrozyten als auch Daten bezüglich der Nährstoffaufnahme, welche mittles 24h-Recall ermittelt wurden herangezogen. Eine regelmäßige Supplementation beeinflusste den Status an Vitamin E, D und ß-Carotin, sowie auf wasserlösliche Vitamine (B1, B2, B6, Folsäure und Vitamin C) als auch auf Magnesium und Calcium positiv.
Natural killer cells generated from human induced pluripotent stem cells mature to CD56brightCD16+NKp80+/- in-vitro and express KIR2DL2/DL3 and KIR3DL1
Creators: name: Euchner, Johanna
name: Sprissler, Jasmin
name: Cathomen, Toni
name: Fürst, Daniel
name: Schrezenmeier, Hubert
name: Debatin, Klaus-Michael
name: Schwarz, Klaus
name: Felgentreff, Kerstin
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: natural killer (NK) cells
subject: hematopoietic progenitor cells (HPC)
subject: NK cell differentiation
subject: OP9-DL1
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Induced pluripotent stem cells
subject: Hematopoietic stem cells
subject: Killer cells, Natural
subject: Induzierte pluripotente Stammzelle
subject: Blutstammzelle
subject: Natürliche Killerzelle

description: The differentiation of human induced pluripotent stem cells (hiPSCs) into T and natural killer (NK) lymphocytes opens novel possibilities for developmental studies of immune cells and in-vitro generation of cell therapy products. In particular, iPSC-derived NK cells gained interest in adoptive anti-cancer immunotherapies, since they enable generation of homogenous populations of NK cells with and without genetic engineering that can be grown at clinical scale. However, the phenotype of in-vitro generated NK cells is not well characterized. NK cells derive in the bone marrow and mature in secondary lymphoid tissues through distinct stages from CD56brightCD16- to CD56dimCD16+ NK cells that represents the most abandoned population in peripheral blood. In this study, we efficiently generated CD56+CD16+CD3- NK lymphocytes from hiPSC and characterized NK-cell development by surface expression of NK-lineage markers. Hematopoietic priming of hiPSC resulted in 31.9% to 57.4% CD34+CD45+ hematopoietic progenitor cells (HPC) that did not require enrichment for NK lymphocyte propagation. HPC were further differentiated into NK cells on OP9-DL1 feeder cells resulting in high purity of CD56brightCD16- and CD56brightCD16+ NK cells. The output of generated NK cells increased up to 40% when OP9-DL1 feeder cells were inactivated with mitomycine C. CD7 expression could be detected from the first week of differentiation indicating priming towards the lymphoid lineage. CD56brightCD16-/+ NK cells expressed high levels of DNAM-1, CD69, natural killer cell receptors NKG2A and NKG2D, and natural cytotoxicity receptors NKp46, NKp44, NKp30. Expression of NKp80 on 40% of NK cells, and a perforin+ and granzyme B+ phenotype confirmed differentiation up to stage 4b. Killer cell immunoglobulin-like receptor KIR2DL2/DL3 and KIR3DL1 were found on up to 3 and 10% of mature NK cells, respectively. NK cells were functional in terms of cytotoxicity, degranulation and antibody-dependent cell-mediated cytotoxicity.
Arabidopsis Glutathione-S-Transferases GSTF11 and GSTU20 function in Aliphatic Glucosinolate Biosynthesis
Creators: name: Zhang, Aiqin
Publisher: name: Zenodo
Year: 2021

description: GSH conjugation with intermediates is required for the biosynthesis of glucosinolate (GSL) by serving as a sulfur supply. Glutathione-S-transferases (GSTs) primarily work on GSH conjugation, suggesting their involvement in GSL metabolism. Although several GSTs, including GSTF11 and GSTU20, have been recently postulated to act in GSL biosynthesis, molecular evidence is lacking. Here, we demonstrated that GSTF11 and GSTU20 play nonredundant, although partially overlapping, roles in aliphatic GSL biosynthesis. In addition, GSTU20 plays a more important role than GSTF11, which is manifested by the greater loss of aliphatic GSLs associated with GSTU20 mutant and a greater number of differentially expressed genes in GSTU20 mutant compared to GSTF11 mutant. Moreover, a double mutation leads to a greater aggregate loss of aliphatic GSLs, suggesting that GSTU20 and GSTF11 may function in GSL biosynthesis in a dosage-dependent manner. Together, our results provide direct evidence that GSTU20 and GSTF11 are critically involved in aliphatic GSL biosynthesis, filling the knowledge gap that has been speculated in recent decades.
description: Total RNA was extracted from three-week-old plants with TRIzol (Invitrogen) and purified using a GeneJET plant RNA purification kit (Thermo Fisher Scientific). RNA integrity and concentration were assessed by gel electrophoresis and using the Qubit® 2.0 Fluorometer (Thermo Fisher Scientific). RNA (1.5 μg) was used for cDNA library preparation with the NEBNext® Ultra™ RNA Library Prep Kit for Illumina® (New England Biolabs, NEB) following the manufacturer's protocol. Library quality was monitored using an Agilent Bioanalyzer 2100 (Agilent Technologies). The cDNA libraries were sequenced on an Illumina HiSeq 2500 platform, and 150-bp paired-end reads were generated. Gene functional annotation was conducted by aligning reads to the Arabidopsis genome sequence (TAIR 10). Following alignment, the count of mapped reads from each sample was derived and normalized as RPKM (reads per kilobase of exon model per million mapped reads). Differentially expressed genes (DEGs) were identified using the DESeq R package (1.10.1). Genes with log2 fold change ≥ 1 and an FDR adjusted p value less than 0.05 were considered DEGs. GO term enrichment of DEGs was analyzed using tools in TAIR.
D4.3_Base-cases definitions and KPI calculation for cement, steel, Bio-CHP and WtE plants with and without capture
Creators: name: Laboratorio Energia Ambiente Piacenza (LEAP)
Publisher: name: Zenodo
Year: 2024

description: The first part of deliverable D4.3 provides a description of the reference facilities considered in the CaLby2030 project, the methodology and the definition of the various key performance indicators (KPIs) considered for energy, technical and economic comparisons. The integration of the various reference plants with a MEA solvent-based CO2 capture system is then described and analyzed. These plants are considered as benchmarks for comparing the performance of Calcium Looping (CaL) systems, which are analyzed in detail from an energy, technical and economic point of view for the different sectors in the last part of the deliverable.
Supplemental Material - Pushing Forward the Transition to a Circular Economy by Adopting an Actor Engagement Lens
Creators: name: Verleye, Katrien
name: De Keyser, Arne
name: Raassens, Néomie
name: Alblas, Alex A.
name: Lit, Fernando C.
name: Huijben, Josephina C. C. M.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental Material for Pushing Forward the Transition to a Circular Economy by Adopting an Actor Engagement Lens by Katrien Verleye, Arne De Keyser, Néomie Raassens, Alex A. Alblas, Fernando C. Lit, and Josephina C. C. M. Huijben in Journal of Service Research
title: Familie in Tieren als projektives Verfahren in der Diagnostik bei Kindern und Jugendlichen mit Intelligenzminderung
Creators: name: Dangl, Sonja
Year: 2009

description: In der vorliegenden Arbeit wurde die Verwendung des projektiven Verfahrens "Familie in Tieren" bei Kindern und Jugendlichen mit Intelligenzminderung untersucht. Bei dem Verfahren Familie in Tieren handelt es sich um ein diagnostisches Instrument, das angesichts seiner qualitativen Verwendung und unter Berücksichtigung wesentlicher Kriterien, vor allem im diagnostischen Prozess bei Kindern bedeutende Hinweise liefern kann. Detaillierte Angaben in Bezug auf die Verwendung von Familie in Tieren bei Menschen mit intellektueller Minderbegabung konnten der recherchierten Literatur nicht entnommen werden. Infolgedessen stellte sich die grundlegende Frage, ob Kinder und Jugendliche mit Intelligenzminderung den Instruktionen des besagten Verfahrens gerecht werden können. Für die Untersuchung wurden von Kindern und Jugendlichen Zeichnungen zu Familie in Tieren angefertigt. Die Gesamtstichprobe der durchgeführten Untersuchung setzte sich aus Probanden mit Intelligenzminderung, aus jenen mit Lernbehinderung und aus Probanden mit Intelligenzminderung zusammen. Den Zeichnungen wurden für die Untersuchung relevante Daten entnommen und entsprechend festgelegter inhaltlicher Kriterien ausgewertet. In Anbetracht der resultierenden Ergebnisse konnten die Probanden mit Intelligenzminderung die an sie gestellten Aufgaben bewältigen, indem sie entsprechendes Instruktionsverständnis zeigten. Infolgedessen konnte vorerst die Frage, ob eine Anwendung bei Kindern und Jugendlichen möglich ist, bestätigt werden. In einem weiteren Schritt wurden die Ergebnisse zweier Stichproben miteinander verglichen, wobei sich eine Stichprobe aus durchschnittlich begabten Probanden und eine aus Probanden mit Intelligenzminderung zusammensetzte. Es galt herauszufinden, ob sich aufgrund des Vergleiches der Ergebnisse Unterschiede bzw. gruppenspezifische Tendenzen zeigten. In Anbetracht der untersuchten Kriterien ist davon auszugehen, dass die Anwendung von Familie in Tieren durchaus in der Diagnostik bei Kindern und Jugendlichen mit Intelligenzminderung möglich ist. Entsprechend den Ergebnissen waren weder relevante Unterschiede noch wesentliche gruppenspezifische Tendenzen nachweisbar, welche bei der Auswertung bzw. Interpretation der Zeichnungen seitens des Diagnostiker zu berücksichtigen wären.
Additional file 15 of KAKU4 regulates leaf senescence through modulation of H3K27me3 deposition in the Arabidopsis genome
Creators: name: Cao, Yaxin
name: Yan, Hengyu
name: Sheng, Minghao
name: Liu, Yue
name: Yu, Xinyue
name: Li, Zhongqiu
name: Xu, Wenying
name: Su, Zhen
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 15
sj-docx-1-opp-10.1177_10781552231177712 - Supplemental material for Nivolumab-induced sensory ganglionopathy
Creators: name: Coskun, Ozlem
name: Sahin, Hasan
name: Yalcin, Selim
name: Sahin, Yekta C.
name: Coskun, Ugur
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-opp-10.1177_10781552231177712 for Nivolumab-induced sensory ganglionopathy by Ozlem Coskun, Hasan Sahin, Selim Yalcin and Yekta C. Sahin, Ugur Coskun in Journal of Oncology Pharmacy Practice
title: From Task Bundles to Task Networks: A New Measurement Approach to Occupational AI Susceptibility with Applications to Gender & Regional Inequality
Creators: name: Owen-Smith, Jason
Publisher: name: Institute for Research on Innovation and Science
Year: 2024
Subjects: classificationCode: 1.2
subject: FOS: Computer and information sciences
classificationCode: 5
subject: FOS: Social sciences
classificationCode: 5.4
subject: FOS: Sociology

description: This working paper presents a new approach to “task-based” studies of technology-driven changes in the US labor market. The occupation task-skill network framework draws on the sociology of work and organizational theory using network science and computational methods.

Initial pilot analyses focus on (1) describing the approach, (2) assessing its implications for measures of AI occupational and task susceptibility, and (3) proposing new data, measurement and analysis efforts to support broader work. Needs for data and measurement capable of fine-grained employer X occupation and regional labor market models of industry exposure and occupational susceptibility to critical and emerging technologies such as AI are discussed along with implications for policy, state workforce and economic development programs.

Data systems and methods capable of capturing, producing, analyzing and communicating timely, granular, local data on employer and industry exposure to new technologies, occupational susceptibility to new technologies and their joint effects on wages, hiring, and job loss are essential to providing policymakers, business leaders and workers with the information they need to capitalize on technology-driven economic change.

The potential consequences of AI for gender wage inequality and existing patterns of geographic inequality are presented in descriptions of potential analyses using the task-skill network approach with public data to concretize key aspects of the framework.
sj-docx-2-tam-10.1177_17588359231177021 – Supplemental material for Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study
Creators: name: Takata, Saori
name: Morikawa, Kei
name: Tanaka, Hisashi
name: Itani, Hidetoshi
name: Ishihara, Masashi
name: Horiuchi, Kazuya
name: Kato, Yasuhiro
name: Ikemura, Shinnosuke
name: Nakagawa, Hideyuki
name: Nakahara, Yoshiro
name: Seki, Yoshitaka
name: Bessho, Akihiro
name: Takahashi, Nobumasa
name: Hayashi, Kentaro
name: Endo, Takeo
name: Takeyama, Kiyoshi
name: Maekura, Toshiya
name: Takigawa, Nagio
name: Kawase, Akikazu
name: Endoh, Makoto
name: Nemoto, Kenji
name: Kishi, Kazuma
name: Soejima, Kenzo
name: Okuma, Yusuke
name: Yoshimura, Kenichi
name: Saigusa, Daisuke
name: Kanai, Yae
name: Ueda, Koji
name: Togashi, Akira
name: Matsutani, Noriyuki
name: Seki, Nobuhiko
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 110203 Respiratory Diseases

description: Supplemental material, sj-docx-2-tam-10.1177_17588359231177021 for Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study by Saori Takata, Kei Morikawa, Hisashi Tanaka, Hidetoshi Itani, Masashi Ishihara, Kazuya Horiuchi, Yasuhiro Kato, Shinnosuke Ikemura, Hideyuki Nakagawa, Yoshiro Nakahara, Yoshitaka Seki, Akihiro Bessho, Nobumasa Takahashi, Kentaro Hayashi, Takeo Endo, Kiyoshi Takeyama, Toshiya Maekura, Nagio Takigawa, Akikazu Kawase, Makoto Endoh, Kenji Nemoto, Kazuma Kishi, Kenzo Soejima, Yusuke Okuma, Kenichi Yoshimura, Daisuke Saigusa, Yae Kanai, Koji Ueda, Akira Togashi, Noriyuki Matsutani and Nobuhiko Seki in Therapeutic Advances in Medical Oncology