cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Insights in Aggregation Behaviour and Lipidmembrane Interaction Potential of Mutants of alpha-Synuclein in vitro
Creators: name: Ruf, Viktoria
name: Kamp, Frits
name: Schmidt, Felix
name: Shi, Song
name: Giese, Armin
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Introduction: The 140 amino acid protein alpha-Synuclein (aSyn) plays a central role in the pathogenesis of PD. Point mutations or duplications and triplications of the synuclein gene SNCA lead to familiar forms of Parkinsonism. Five point mutations have been described to date: A30P, E46K, H50Q, G51D,[for full text, please go to the a.m. URL]
description: 60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)
Assessment of Quality management practices in construction projects: the case of AACRA
Creators: name: Bitew, Dereje
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2019

description: This study was mainly set out with a general purpose to assess the quality management practices and major quality management challenges in road construction projects at AACRA. To achieve its objective, the study employed both descriptive and explanatory research and both primary and secondary data were used. Questionnaires, interview, and document review were, therefore, used as data collection tools. Furthermore, it employed purposive sampling techniques to draw its samples. The survey questionnaire was designed based on the literature and on the information collected through the document review of the project. The survey questionnaire was distributed to 60 project implementation team members who were selected purposively among them 55 respondents were responded, which represented a response rate of 91.67%. The data gathered through the questionnaire was analyzed by Statistical Package for Social Science (SPSS). The generated data was analyzed using tables, frequency, percentage, and multiple regression approaches. The result of the study indicated that AACRA does not employ all stages of quality management process, tools and techniques. Since they use only Inspection are found to be the major quality management tools and techniques used to control quality of project. Qualified and experiences personnel, top management support, communication with stakeholders, quality of materials and equipments used in the project construction and conformance to specification are identified as the top factors in the determinant of the quality of road construction projects. In the study it is examined that various quality assurance measures were taken starting from defining project objectives and to monitoring and the tasks that were carried out mostly in monthly, quarterly monitoring at specified level with management members involvement. It was also identified that some barriers of quality management; inadequate management support, problems with contractors performance, unrealistic deadline, lack of quality management policy, and right of way were the major once. The study also recommended that AACRA to have separate quality management policy in order to undertake complete project quality management process, enhance management involvement, capacity building on project management skills for successful implementation of road construction
Un análisis del concepto de muerte y del sentido de la vida en Ludwig Wittgenstein y Federico Nietzche.
Creators: name: Gámez Lara, Sandra Milena
Publisher: name: Universidad de Cartagena
Year: 2011
Subjects: Filosofía del Lenguaje
Wittgenstein, Ludwig - Critica e interpretación
Lógica
Lenguaje

description: Tesis (Filosofo) -- Universidad de Cartagena. Facultad de Ciencias Humanas. Programa de Filosofía.
description: Una de las constantes preguntas que rigen la vida del hombre es la pregunta por la muerte. Esta pregunta encierra aspectos como el momento, la manera o el por qué debe ocurrir. Además cuestiones mucho más complejas, por ejemplo, qué viene después de ella. Estas preguntas no solo van dirigidas a la muerte como destino final, sino que también tocan a los acontecimientos de la vida cotidiana y a la vida en sí misma. ¿Si voy a morir qué sentido tiene hacer esto o lo otro? ¿Qué sentido tiene vivir de todos modos? Pensar que con la muerte todo termina es algo que genera angustia, en tanto, implica el dejar de existir, hecho que resulta desconsolador. Esto lleva a pensar que el concepto de muerte represente para el hombre algo más que el simple fin de las actividades fisiológicas. Además de la vida biológica hay algo más que es tocado no sólo por la muerte sino por su sombra. La válvula de escape más común a esta presión existencial es la creencia en una vida más allá de la muerte. Es así como algunos seres humanos tratan de resistirse a morir definitivamente. Frente al término “muerte” el hombre opta por creer que esta es sólo física y que existe una vida espiritual que se prolonga después de ella, con la inmortalidad del alma.
title: ER chaperone Sigma 1 receptors (SigR1) in the pathogenesis of amyotrophic lateral sclerosis (ALS) and Huntington’s disease (HD)
Creators: name: Gowami, Anand
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Abnormal accumulations of misfolded proteins that elicit endoplasmic reticulum (ER) stress are major pathological hallmarks of Amyotrophic lateral sclerosis (ALS) and Huntington’s disease (HD). Mutations in the endoplasmic reticulum (ER) chaperon sigma receptor 1 (SigR1) cause familial ALS and[for full text, please go to the a.m. URL]
description: 60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)
Microfluidic devices as novel in vitro platforms in the context of pre-clinical and toxicology studies
Creators: name: ODDO, ARIANNA
Publisher: name: Monash University
Year: 2022
Subjects: Nanomaterials
Nanomedicine
Nanotoxicology, health and safety
Biochemistry and cell biology not elsewhere classified
Toxicology (incl. clinical toxicology)

description: My PhD thesis aims to develop alternative approaches to animal testing in the context of pre-clinical and toxicological studies. This research focused on organ-on-a-chip technology as an emerging screening platform to study the interactions between human organs, nanoparticles, and viruses that can infect the human brain.
title: CD74 expression in tumor cells is a positive prognostic marker for brain metastases patients
Creators: name: Zeiner, Pia S.
name: Bernatz, Simon
name: Ronellenfitsch, Michael W.
name: Zinke, Jenny
name: Thorsen, Frits
name: Plate, Karl H.
name: Beschorner, Rudi
name: Weide, Benjamin
name: Wischhusen, Jörg
name: Mittelbronn, Michel
name: Harter, Patrick N.
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: The macrophage migration inhibitory factor (MIF) receptor CD74 (also known as invariant chain) is upregulated in numerous peripheral neoplasms and has also been described as one of the most overexpressed molecules in primary brain tumors. While under certain circumstances MIF-CD74 interactions, lead[for full text, please go to the a.m. URL]
description: 60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)
Memory Remains: Understanding Collective Memory in the Digital Age
Creators: name: García-Gavilanes, Ruth
name: Mollgaard, Anders
name: Tsvetkova, Milena
name: Yasseri, Taha
Publisher: name: arXiv
Year: 2016
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Computers and Society (cs.CY)
subject: Social and Information Networks (cs.SI)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Recently developed information communication technologies, particularly the Internet, have affected how we, both as individuals and as a society, create, store, and recall information. Internet also provides us with a great opportunity to study memory using transactional large scale data, in a quantitative framework similar to the practice in statistical physics. In this project, we make use of online data by analysing viewership statistics of Wikipedia articles on aircraft crashes. We study the relation between recent events and past events and particularly focus on understanding memory triggering patterns. We devise a quantitative model that explains the flow of viewership from a current event to past events based on similarity in time, geography, topic, and the hyperlink structure of Wikipedia articles. We show that on average the secondary flow of attention to past events generated by such remembering processes is larger than the primary attention flow to the current event. We are the first to report these cascading effects.
description: Under Review
Development of Novel Kinase Inhibitors as Therapeutics
Creators: name: MA, XIAO
Publisher: name: Monash University
Year: 2022
Subjects: Pharmaceutical sciences
Organic chemical synthesis

description: Kinases are important classes of proteins that are involved in many diseases. The understanding of their biological roles has been a challenging and ongoing journey. 20 years ago, the first kinase-targeting drug met the market, and to date there are more than 60 of them. This thesis describes the development of novel kinase-targeting molecules that are potentially more effective and safer for the treatment of cancer and thrombosis. Excitingly, the lead molecule developed cures a type of lymphoma in mice.
Estudio de factibilidad para el montaje de un centro de diagnóstico para el tratamiento del dolor y rehabilitación en la ciudad de Cartagena de Indias
Creators: name: Caballero Brieva, Hadit
name: Morelos Gómez, Esperanza
Publisher: name: Universidad de Cartagena
Year: 2001
Subjects: Estudio de mercado
Estudios de factibilidad
Estudio financiero
Localización

description: Tesis (Administrador de Empresas) -- Universidad de Cartagena. Facultad de Ciencias Económicas. Programa de Administración de Empresas. 2001
description: El presente estudio tiene por objeto determinar la factibilidad de mercado, técnica, administrativa, legal, financiera, económico social y ambiental del montajes de una clínica especializada en el tratamiento del dolor en la ciudad de Cartagena.
Hierarchical data-driven approach to fitting numerical relativity data for nonprecessing binary black holes with an application to final spin and radiated energy
Creators: name: Jiménez-Forteza, Xisco
name: Keitel, David
name: Husa, Sascha
name: Hannam, Mark
name: Khan, Sebastian
name: Pürrer, Michael
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Numerical relativity is an essential tool in studying the coalescence of binary black holes (BBHs). It is still computationally prohibitive to cover the BBH parameter space exhaustively, making phenomenological fitting formulas for BBH waveforms and final-state properties important for practical applications. We describe a general hierarchical bottom-up fitting methodology to design and calibrate fits to numerical relativity simulations for the three-dimensional parameter space of quasicircular nonprecessing merging BBHs, spanned by mass ratio and by the individual spin components orthogonal to the orbital plane. Particular attention is paid to incorporating the extreme-mass-ratio limit and to the subdominant unequal-spin effects. As an illustration of the method, we provide two applications, to the final spin and final mass (or equivalently: radiated energy) of the remnant black hole. Fitting to 427 numerical relativity simulations, we obtain results broadly consistent with previously published fits, but improving in overall accuracy and particularly in the approach to extremal limits and for unequal-spin configurations. We also discuss the importance of data quality studies when combining simulations from diverse sources, how detailed error budgets will be necessary for further improvements of these already highly accurate fits, and how this first detailed study of unequal-spin effects helps in choosing the most informative parameters for future numerical relativity runs.
description: 23 pages, 31 figures, 15 tables; data and example implementations as supplementary material. Updated to match PRD version
RG Flows and Bifurcations
Creators: name: Gukov, Sergei
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Interpreting RG flows as dynamical systems in the space of couplings we produce a variety of constraints, global (topological) as well as local. These constraints, in turn, rule out some of the proposed RG flows and also predict new phases and fixed points, surprisingly, even in familiar theories such as O(N) model, QED-3, or QCD-4.
description: 62 pp, 25 figures, 6 tables; remarks and references added
Improved Control Strategies for Intermittent Contact Mode Atomic Force Microscopes
Creators: name: Coraggio, Marco
name: Homer, Martin
name: Payton, Oliver D.
name: di Bernardo, Mario
Publisher: name: arXiv
Year: 2016
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Atomic force microscopes have proved to be fundamental research tools in many situations where a gentle imaging process is required, and in a variety of environmental conditions, such as the study of biological samples. Among the possible modes of operation, intermittent contact mode is one that causes less wear to both the sample and the instrument; therefore, it is ideal when imaging soft samples. However, intermittent contact mode is not particularly fast when compared to other imaging strategies. In this paper, we introduce three enhanced control approaches, applied at both the dither and z-axis piezos, to address the limitations of existing control schemes. Our proposed strategies are able to eliminate different image artefacts, automatically adapt scan speed to the sample being scanned and predict its features in real time. The result is that both the image quality and the scan time are improved.
description: 11 pages
Amtliche Mitteilungen der Universität Dortmund Nr. 03/2004
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Dortmund
Year: 2004
Subjects: subject: 080

description: Amtlicher Teil: Ordnung zur Änderung der Fakultätsordnung für die Wirtschafts- und Sozialwissenschaftliche Fakultät der Universität Dortmund vom 28.01.2004
description: Nichtamtlicher Teil: Frauenförderplan der Fakultät Bauwesen der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Fakultät für Elektrotechnik und Informationstechnik der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Fakultät Humanwissenschaften und Theologie der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Fakultät Kulturwissenschaften der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Fakultät Maschinenbau der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Fakultät Raumplanung der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Fakultät Rehabilitationswissenschaften der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Universitätsbibliothek der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Verwaltung der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan der Wirtschafts- und Sozialwissenschaftlichen Fakultät der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Chemie der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Chemietechnik der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Erziehungswissenschaften und Soziologie der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Informatik der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Mathematik der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Musik, Kunst, Textilgestaltung, Sport und Geographie der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Physik der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Fachbereichs Statistik der Universität Dortmund
description: Nichtamtlicher Teil: Frauenförderplan des Hochschulrechenzentrums der Universität Dortmund
description: Amtliche Mitteilungen der Universität Dortmund ; 3, 2004
An algebra of synchronous atomic steps
Creators: name: Hayes, Ian J.
name: Colvin, Robert
name: Meinicke, Larissa
name: Winter, Kirsten
name: Velykis, Andrius
Publisher: name: arXiv
Year: 2016
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: D.2.4; F.3.1

description: This research started with an algebra for reasoning about rely/guarantee concurrency for a shared memory model. The approach taken led to a more abstract algebra of atomic steps, in which atomic steps synchronise (rather than interleave) when composed in parallel. The algebra of rely/guarantee concurrency then becomes an interpretation of the more abstract algebra. Many of the core properties needed for rely/guarantee reasoning can be shown to hold in the abstract algebra where their proofs are simpler and hence allow a higher degree of automation. Moreover, the realisation that the synchronisation mechanisms of standard process algebras, such as CSP and CCS/SCCS, can be interpreted in our abstract algebra gives evidence of its unifying power. The algebra has been encoded in Isabelle/HOL to provide a basis for tool support.
Assessment of Risk Management Practices of Ethiopian Public Health Institute
Creators: name: Nigusse, Bisrat
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2018

description: Project management is used as a significant skill in many industries. For this reason, the knowledge of projects and their management are of high importance. Project risk management is the process of identifying, analyzing and then responding to any risk that arises over the life cycle of a project to help the project remain on track and meet its goal. Poor risk management as a whole is one of the major aspects causing projects to collapse, and this has become an obstacle to each and every project that is being developed nowadays. The healthcare industry faces many of the same challenges as other industries, with some very particular stress points. Ethiopian Public Health Institute have completed and now also implementing various health care projects with different constraints including scope, time, cost, quality and risk in order to improve quality of health care and enhance the capacity of the health sector at all levels of the system. The main objective of this study was to assess the risk management practices in health care projects under Ethiopian Public Health Institute. Descriptive research design was used to answer the extent of risk management practice in health care projects and to see the associated factors affecting the risk management practice. The target population for this study was all members of the project and other related officers in Ethiopian Public Health Institute from which the sample population was drawn by using purposive sampling technique. This study used both primary and secondary data source and quantitative method to address the objective of the study by using self administered questionnaires as a data collection tool. The collected data was analyzed using SPSS version.20 software, which entails calculating frequency, percentage, mean, standard deviation and variability. As the finding of this study, the risk management practice in various projects in Ethiopian public health institute mainly the risk planning, identification, analysis, response & monitoring was moderately implemented with the average mean score of 3.20 and SD of 1.23. However, the utilization of risk management tools and techniques to manage the project risk were very low with a mean score and standard deviation 2.58 & 0.93 respectively. Regarding policy and strategies most of the respondents disagree and uncertain on the presence of policy or guideline that recommend how to manage unexpected uncertainties and standard risk management practices in these project organization. Thus this study recommends that standard risk management practice should be backed with strategies and guidelines and implemented at every stage of the project by integrating with the project plan and with the involvement of all project team members and stakeholders.
Gagea sivasica Hamzaoglu 2008
Creators: name: Tekşen, Mehtap
name: Erkul, Seher Karaman
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Liliales
Liliaceae
Gagea
Gagea sivasica

description: Gagea sivasica Hamzaoğlu, Turk. J. Bot. 32: 261 (2008)
 Type: — TURKEY. Sivas. Hafik, Tödürge Lake, around Resort of Cumhuriyet University, 1310 m, damp grassy places on gypsaceous rocks, 7 May 2006, Hamzaoğlu, Aksoy & Budak 3832 (holotype BOZOK; isotypes BOZOK, ERCH, GAZI, ANK, HUB!).
 Specimens seen: — TURKEY. Sivas: Hafik-Zara, Tödürge lake, around Resort of Cumhuriyet University, gypsaceous rocks, 1304 m, 25 April 2011, M. Tekşen 2771 & S. Karaman (GAZI!); ibidem, 27 June 2011, M. Tekşen 2828 & S. Karaman (AKSU!); Hafik, Tödürge lake, around Resort of Cumhuriyet University, wet gypsaceous rocks, 1310 m, 7 May 2006, Hamzaoğlu 3832 (GAZI!, ANK!).
 Flowering time: — April–May.
 Habitat: — Gypsaceous rocks, rocky places, 1304–1310 m.
 Distribution: — Endemic to Turkey (Central Anatolia). Irano-Turanian element.
 IUCN category: — Endangered, EN - B2ab (iii).
description: Published as part of Tekşen, Mehtap & Erkul, Seher Karaman, 2015, The synopsis of the genus Gagea (Liliaceae) in Turkey, pp. 101-129 in Phytotaxa 230 (1) on page 124, DOI: 10.11646/phytotaxa.230.2.1, http://zenodo.org/record/13630814
Magnetospheric Multiscale Observations of Electron Vortex Magnetic Hole in the Magnetosheath Turbulent Plasma
Creators: name: Huang, S. Y.
name: Sahraoui, F.
name: Yuan, Z. G.
name: He, J. S.
name: Zhao, J. S.
name: Contel, O. Le
name: Deng, X. H.
name: Zhou, M.
name: Fu, H. S.
name: Pang, Y.
name: Shi, Q. Q.
name: Lavraud, B.
name: Yang, J.
name: Wang, D. D.
name: Yu, X. D.
name: Pollock, C. J.
name: Giles, B. L.
name: Torbert, R. B.
name: Russell, C. T.
name: Goodrich, K. A.
name: Gershman, D. J.
name: Moore, T. E.
name: Ergun, R. E.
name: Khotyaintsev, Y. V.
name: Lindqvist, P. -A.
name: Strangeway, R. J.
name: Magnes, W.
name: Bromund, K.
name: Leinweber, H.
name: Plaschke, F.
name: Anderson, B. J.
name: Burch, J. L.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Space Physics (physics.space-ph)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: We report the observations of an electron vortex magnetic hole corresponding to a new type of coherent structures in the magnetosheath turbulent plasma using the Magnetospheric Multiscale (MMS) mission data. The magnetic hole is characterized by a magnetic depression, a density peak, a total electron temperature increase (with a parallel temperature decrease but a perpendicular temperature increase), and strong currents carried by the electrons. The current has a dip in the center of the magnetic hole and a peak in the outer region of the magnetic hole. The estimated size of the magnetic hole is about 0.23 \r{ho}i (~ 30 \r{ho}e) in the circular cross-section perpendicular to its axis, where \r{ho}i and \r{ho}e are respectively the proton and electron gyroradius. There are no clear enhancement seen in high energy electron fluxes, but an enhancement in the perpendicular electron fluxes at ~ 90° pitch angles inside the magnetic hole is seen, implying that the electron are trapped within it. The variations of the electron velocity components Vem and Ven suggest that an electron vortex is formed by trapping electrons inside the magnetic hole in the circular cross-section (in the M-N plane). These observations demonstrate the existence of a new type of coherent structures behaving as an electron vortex magnetic hole in turbulent space plasmas as predicted by recent kinetic simulations.
description: 19 pages, 4 figures
New Construction of Eigenstates and Separation of Variables for SU(N) Quantum Spin Chains
Creators: name: Gromov, Nikolay
name: Levkovich-Maslyuk, Fedor
name: Sizov, Grigory
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: Quantum Algebra (math.QA)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We conjecture a new way to construct eigenstates of integrable XXX quantum spin chains with SU(N) symmetry. The states are built by repeatedly acting on the vacuum with a single operator Bgood(u) evaluated at the Bethe roots. Our proposal serves as a compact alternative to the usual nested algebraic Bethe ansatz. Furthermore, the roots of this operator give the separated variables of the model, explicitly generalizing Sklyanin's approach to the SU(N) case. We present many tests of the conjecture and prove it in several special cases. We focus on rational spin chains with fundamental representation at each site, but expect many of the results to be valid more generally.
description: 38 pages; v2: added proof for SU(2), minor corrections; v3: typos fixed, references added; v4: minor corrections
Backreaction Issues in Axion Monodromy and Minkowski 4-forms
Creators: name: Valenzuela, Irene
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We clarify the differences between the usual Kaloper-Sorbo description of axion monodromy and the effective axionic potential in terms of Minkowski 4-forms derived in string compactifications. The fact that the metric of the 3-form fields coming from string theory is field dependent (unlike in Kaloper-Sorbo) leads to the backreaction issues recently studied in axion monodromy models within string theory. We reanalyse these problems in terms of the 4-forms focusing on the case in which the non-periodic scalars backreact on the Kahler metric of the inflaton reducing the physical field range. In the closed string sector of Type II Calabi-Yau compactifications with fluxes the metric becomes field dependent precisely when $Δϕ\sim M_p$, independently of the choice of fluxes. We propose, however, some counter-examples to this universal behaviour by including open string fields.
description: 31 pages, 1 figure, v2: typos corrected, comments and references added
Developing Targeted Drug Delivery Systems for Brain Cancer Treatment Using Porous Silicon Nanoparticles
Creators: name: Luo, Meihua
Publisher: name: Monash University
Year: 2022
Subjects: Pharmaceutical sciences
Medical biotechnology not elsewhere classified
Nanomedicine

description: Glioblastoma (GBM) is one of the deadliest malignant adult brain cancers. The key challenges include the limited blood-brain barrier (BBB) permeability of the therapeutics, inadequate drug accumulation in the brain and high recurrence rate of GBM. This work evaluates porous silicon nanoparticles with different functionalisations as targeted drug delivery systems. They have a selective and enhanced cellular internalisation and deliver chemotherapy drugs through the BBB for GBM tumour killing. These nanoparticles can also inhibit GBM cell migration, even in the absence of drug loading. These highlight their potential as targeted anticancer drug carriers and migration inhibitors for GBM treatment.
Hamiltonian Dynamics of Semiclassical Gaussian Wave Packets in Electromagnetic Potentials
Creators: name: King, Nolan
name: Ohsawa, Tomoki
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 37J15, 70G45, 70H33, 81Q05, 81Q20, 81Q70

description: We extend our previous work on symplectic semiclassical Gaussian wave packet dynamics to incorporate electromagnetic interactions by including a vector potential. The main advantage of our formulation is that the equations of motion derived are naturally Hamiltonian. We obtain an asymptotic expansion of our equations in terms of $\hbar$ and show that our equations have $\mathcal{O}(\hbar)$ corrections to those presented by Zhou, whereas ours also recover the equations of Zhou in the case of a linear vector potential and quadratic scalar potential. One and two dimensional examples of a particle in a magnetic field are given and numerical solutions are presented and compared with the classical solutions and the expectation values of the corresponding observables as calculated by the Egorov or Initial Value Representation (IVR) method. We numerically demonstrate that the $\mathcal{O}(\hbar)$ correction terms improve the accuracy of the classical or Zhou's equations for short times in the sense that our solutions converge to the expectation values calculated using the Egorov/IVR method faster than the classical solutions or those of Zhou as $\hbar \to 0$.
description: 16 pages, 6 figures
A generalization of the S-function method applied to a Duffing-Van der Pol forced oscillator
Creators: name: Duarte, L. G. S.
name: da Mota, L. A. C. P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: Chaotic Dynamics (nlin.CD)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: In [1,2] we have developed a method (we call it the S-function method) that is successful in treating certain classes of rational second order ordinary differential equations (rational 2ODEs) that are particularly `resistant' to canonical Lie methods and to Darbouxian approaches. In this present paper, we generalize the S-function method making it capable of dealing with a class of elementary 2ODEs presenting elementary functions. Then, we apply this method to a Duffing-Van der Pol forced oscillator, obtaining an entire class of first integrals.
FiveThirtyEight/Ipsos 2022 Election Tracking Survey Wave 6: Pre-Election
Creators: name: FiveThirtyEight
Publisher: name: Roper Center for Public Opinion Research
Year: 2023

description: Most important issues facing America (4); issues most concerning to the respondent (3); inflation (3); unemployment (3); economic inequality (3); political extremism/polarization (3); government budget/deficit (3); taxes (3), foreign conflicts/terrorism (3); education (3); immigration (3); race/racism (3); healthcare (3); coronavirus (COVID-19) (3); opioid/drug addiction (3); abortion (3); crime/gun violence (3); climate change (3); natural disasters (3); election security/fraud (3); issues covered in the news (20); 2022 midterms (12); favorable/unfavorable opinion of political leaders and institutions (14); perceived values and beliefs of the Republican/Democratic Party (12); Republican/Democratic control of Congress (6); media coverage of 2022 midterms (7); has seen political ads/contacted by a political campaign in the last month (5); seen an ad for an issue/organization (1); main source of news (1); 2020 presidential vote (1); past midterm elections (3).
Simplified simplicial depth for regression and autoregressive growth processes
Creators: name: Kustosz, Christoph P.
name: Müller, Christine H.
name: Wendler, Martin
Publisher: name: Technische Universität Dortmund
Year: 2014
Subjects: subject: alternating sign
subject: consistency
subject: asymptotic distribution
subject: robustness
subject: distribution-free test
subject: 310
subject: 330
subject: 620

description: We simplify simplicial depth for regression and autoregressive growth processes in two directions. At first we show that often simplicial depth reduces to counting the subsets with alternating signs of the residuals. The second simplification is given by not regarding all subsets of residuals. By consideration of only special subsets of residuals, the asymptotic distributions of the simplified simplicial depth notions are normal distributions so that tests and confidence intervals can be derived easily. We propose two simplifications for the general case and a third simplification for the special case where two parameters are unknown. Additionally, we derive conditions for the consistency of the tests. We show that the simplified depth notions can be used for polynomial regression, for several nonlinear regression models, and for several autoregressive growth processes. We compare the efficiency and robustness of the different simplified versions by a simulation study concerning the Michaelis-Menten model and a nonlinear autoregressive process of order one.
description: Discussion Paper / SFB 823;33/2014
Técnicas para la administración científica del inventario y recomendaciones para su implantación en el Almacén de la Cruz Roja Colombiana - Seccional Bolívar
Creators: name: Ávila Reyes, Jhan
name: Guzmán Súarez, Manuel
Publisher: name: Universidad de Cartagena
Year: 1991
Subjects: Cruz Roja
Colombia
Inventarios
Control Inventarios

description: Tesis (Administrador de Empresas). Universidad de Cartagena. Facultad de Ciencias Económicas. Programa de Administración de Empresas. 1991
description: El presente estudio tiene por objeto proporcionar las técnicas para la administración científica del inventario a la Cruz Roja Colombiana seccional Bolívar, buscando establecer todos los procedimientos óptimos que no lleven a programar una mejor adquisición de existencias de artículos y al vez, buscar las políticas mas recomendables para el buen manejo y control de inventarios.
Assessment of the Practice and Challenges of Information Technology Project Management: A Case in Ministry of Communication and Information Technology E-Procurement Software Project
Creators: name: Missker, Addiskidan
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2018

description: The purpose of this study is to assess the practice and challenges of Information Technology Project management of Ministry of Communication and Information Technology E-Procurement Software Project. The research purposefully takes the whole population of project management team, both from MCIT and Perago, who are involved in the management process including the two project managers. The researcher used both primary and secondary data to achieve the intended research objectives. The primary data collected through self developed Likert scale structured questionnaire for the project process groups and an adapted Likert scale structured questionnaire for the major challenges of IT projects were distributed among six team members of the project management team including the project manager from MCIT and fifteen project management team members from Perago, the outsourced company including the project manager. The questionnaires were distributed online by using Google Form and the respondents were asked for their agreement/disagreement on existence and extent of the challenges in the project. Secondary data collected from compiled Terms of Reference and Status report Documents and had interviewed the two project managers. Data were analyzed using Google Form and Microsoft Excel and interpreted for percentage, mean and standard deviation. The findings of this study revealed that the project management practices were properly implemented as of the project management process groups except it missed proper feasibility study at initial stage and identified these major challenges insufficient skills within the team , delay in document approval ,older legacy systems issues ,too much project status reporting issues and insufficient technical knowledge within team. The feasibility study should be conducted in order to establish the validity of the benefits of the project locally by MCIT, different government organizations should prepare a suitable environment for the development of projects so as to understand and design the best solution for the existing unstructured system, prepare a project management team members meeting after each deliverables in order that the can go through the document with the reviewer and make amendments at the same time, have a IT training plan for team members to keep them updated with the latest technologies and project management training to help them to improve their ability of managing project, solving and analyzing a problem. ,and use tools like softwares to generate the report easily and also delegate a person who deals with status report preparation to the team.
Modular forms, Schwarzian conditions, and symmetries of differential equations in physics
Creators: name: Abdelaziz, Y.
name: Maillard, J. -M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 34M55, 47Exx, 32Hxx, 32Nxx, 34Lxx, 34Mxx, 14Kxx, 14H52

description: We give examples of infinite order rational transformations that leave linear differential equations covariant. These examples are non-trivial yet simple enough illustrations of exact representations of the renormalization group. We first illustrate covariance properties on order-two linear differential operators associated with identities relating the same $_2F_1$ hypergeometric function with different rational pullbacks. We provide two new and more general results of the previous covariance by rational functions: a new Heun function example and a higher genus $_2F_1$ hypergeometric function example. We then focus on identities relating the same hypergeometric function with two different algebraic pullback transformations: such remarkable identities correspond to modular forms, the algebraic transformations being solution of another differentially algebraic Schwarzian equation that emerged in a paper by Casale. Further, we show that the first differentially algebraic equation can be seen as a subcase of the last Schwarzian differential condition, the restriction corresponding to a factorization condition of some associated order-two linear differential operator. Finally, we also explore generalizations of these results, for instance, to $_3F_2$, hypergeometric functions, and show that one just reduces to the previous $_2F_1$ cases through a Clausen identity. In a $_2F_1$ hypergeometric framework the Schwarzian condition encapsulates all the modular forms and modular equations of the theory of elliptic curves, but these two conditions are actually richer than elliptic curves or $_2F_1$ hypergeometric functions, as can be seen on the Heun and higher genus example. This work is a strong incentive to develop more differentially algebraic symmetry analysis in physics.
description: 43 pages
Diagnostics for Targeted Drug Delivery in the Gastrointestinal Tract
Creators: name: Ali, Heba Saleh Abdellah
Publisher: name: Monash University
Year: 2022
Subjects: Pharmaceutical sciences

description: Colon-specific drug delivery systems are considered effective strategies for the treatment of colon diseases such as colorectal cancer, inflammatory bowel disease, and irritable bowel syndrome. These systems are also beneficial for the oral delivery of labile molecules such as proteins and peptides into the colon. In this thesis, we have been working on developing a new colon drug delivery system with improved site-specificity based on cyclization-activated prodrug designs. We succeeded in synthesising a new chemical probe that was able to protect 60% of the payload from being released in the pH conditions simulating the upper gastrointestinal tract. We also investigated the potential use of those prodrug designs to develop a long-acting subcutaneous injection for treating chronic diseases.
Inspiration, Captivation, and Misdirection: Emergent Properties in Networks of Online Navigation
Creators: name: Gildersleve, Patrick
name: Yasseri, Taha
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Computers and Society (cs.CY)
subject: Social and Information Networks (cs.SI)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The World Wide Web (WWW) has fundamentally changed the ways billions of people are able to access information. Thus, understanding how people seek information online is an important issue of study. Wikipedia is a hugely important part of information provision on the web, with hundreds of millions of users browsing and contributing to its network of knowledge. The study of navigational behaviour on Wikipedia, due to the site's popularity and breadth of content, can reveal more general information seeking patterns that may be applied beyond Wikipedia and the Web. Our work addresses the relative shortcomings of existing literature in relating how information structure influences patterns of navigation online. We study aggregated clickstream data for articles on the English Wikipedia in the form of a weighted, directed navigational network. We introduce two parameters that describe how articles act to source and spread traffic through the network, based on their in/out strength and entropy. From these, we construct a navigational phase space where different article types occupy different, distinct regions, indicating how the structure of information online has differential effects on patterns of navigation. Finally, we go on to suggest applications for this analysis in identifying and correcting deficiencies in the Wikipedia page network that may also be adapted to more general information networks.
Social Complex Contagion in Music Listenership: A Natural Experiment with 1.3 Million Participants
Creators: name: Ternovski, John
name: Yasseri, Taha
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Computers and Society (cs.CY)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Can live music events generate complex contagion in music streaming? This paper finds evidence in the affirmative, but only for the most popular artists. We generate a novel dataset from Last.fm, a music tracking website, to analyse the listenership history of 1.3 million users over a two-month time horizon. We use daily play counts along with event attendance data to run a regression discontinuity analysis in order to show the causal impact of concert attendance on music listenership among attendees and their friends network. First, we show that attending a music artist's live concert increases that artist's listenership among the attendees of the concert by approximately 1 song per day per attendee (p-value<0.001). Moreover, we show that this effect is contagious and can spread to users who did not attend the event. However, the extent of contagion depends on the type of artist. We only observe contagious increases in listenership for well-established, popular artists (.06 more daily plays per friend of an attendee [p<0.001]), while the effect is absent for emerging stars. We also show that the contagion effect size increases monotonically with the number of friends who have attended the live event.
description: Preprint, under review
Porous Silicon Microneedles and Micropillars for Biomedical Applications
Creators: name: TABASSUM, NAZIA
Publisher: name: Monash University
Year: 2022
Subjects: Biomaterials
Nanomedicine

description: " This thesis examines microfabrication approaches for innovative delivery of drugs across the skin. It describes the fabrication and testing of silicon-based microneedles and micropillars as a basis for new adaptable drug delivery and imaging platforms for future biomedical and clinical applications."
Estrategias fundamentales para la formación de los reinsertados que permita la preparación del capital humano en el manejo de los recursos que propone el acuerdo de la Habana (Cuba)
Creators: name: Fernández Ávila, Laura Stefany
name: Chiquillo Girón, Dagoberto
Publisher: name: Universidad de Cartagena
Year: 2016
Subjects: Capital humano
Recursos humanos
Administración de personal

description: Tesis (Administrador de Empresas).--Universidad de Cartagena. Facultad de Ciencias Económicas. Programa de Administración de Empresas a Distancia, 2016
description: El presente trabajo pretende determinar las estrategias fundamentales para la formación de los reinsertados que permita la preparación del capital humano en el manejo de los recursos que propone el acuerdo de la Habana.
Emergence of particle clusters in a one-dimensional model: connection to condensation processes
Creators: name: Burman, Matthew
name: Carpenter, Daniel
name: Jack, Robert L.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We discuss a simple model of particles hopping in one dimension with attractive interactions. Taking a hydrodynamic limit in which the interaction strength increases with the system size, we observe the formation of multiple clusters of particles, each containing a finite fraction of the all the particles in the system. These clusters are correlated in space, and the system has a self-similar (fractal) structure. These results are related to condensation phenomena in mass transport models and to a recent mathematical analysis of the hydrodynamic limit in a related model.
description: 16 pages
Evaluación del impacto de la NTC ISO 14001 : 04 en la optimización de recursos ambientales en las empresas de la construcción.
Creators: name: Martinez Montero, Dina Alejandra
name: Melo Jimenez, Vanessa
name: Quiñones Bolaños, Edgar (Director)
Publisher: name: Universidad de Cartagena
Year: 2008
Subjects: Protección del medio ambiente - Caribe (Región, Colombia)
Impacto ambiental; Materiales de construcción - Producción
Construcción

description: Tesis (Ingeniero Civil) -- Universidad de Cartagena. Facultad de Ciencias E Ingenierías. Programa de Ingeniería Civil. 2008.
description: El presente estudio tiene por objeto evaluar el impacto de la implementacion de la ISO 14001:04 en la optimizacion de los recursos ambientales al interior de una empresas de la construcción.