cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Graded Brauer groups of a groupoid with involution
Creators: name: Moutuou, El-kaïoum M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Functional Analysis (math.FA)
subject: General Topology (math.GN)
subject: K-Theory and Homology (math.KT)
subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 22-XX, 46KXX, 22A22

description: We define a group $RBr(\mathcal{G})$ containing, in a sense, the graded complex and orthogonal Brauer groups of a locally compact groupoid $\mathcal{G}$ equipped with an involution. When the involution is trivial, we show that the new group naturally provides a generalization of Donovan-Karoubi's graded orthogonal Brauer group $GBrO$. More generally, it is shown to be a direct summand of the well-known graded complex Brauer goup. In addition, we prove that $RBr(\mathcal{G})$ identifies with a direct sum of a Real cohomology group and the abelian group $RExt(\mathcal{G},U(1))$ of Real graded $U(1)$-central extensions. A cohomological picture is then given.
description: 47 pages, minor corrections
Finite-size scaling considerations on the ground state microcanonical temperature in entropic sampling simulations
Creators: name: Caparica, Álvaro de Almeida
name: DaSilva, Cláudio José
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: In this work we discuss the behavior of the microcanonical temperature $\frac{\partial S(E)}{\partial E}$ obtained by means of numerical entropic sampling studies. It is observed that in almost all cases the slope of the logarithm of the density of states $S(E)$ is not infinite in the ground state, since as expected it should be directly related to the inverse temperature $\frac{1}{T}$. Here we show that these finite slopes are in fact due to finite-size effects and we propose an analytic expression $a\ln(bL)$ for the behavior of $\frac{\varDelta S}{\varDelta E}$ when $L\rightarrow\infty$. To test this idea we use three distinct two-dimensional square lattice models presenting second-order phase transitions. We calculated by exact means the parameters $a$ and $b$ for the two-states Ising model and for the $q=3$ and $4$ states Potts model and compared with the results obtained by entropic sampling simulations. We found an excellent agreement between exact and numerical values. We argue that this new set of parameters $a$ and $b$ represents an interesting novel issue of investigation in entropic sampling studies for different models.
Oscillation and the mean ergodic theorem for uniformly convex Banach spaces
Creators: name: Avigad, Jeremy
name: Rute, Jason
Publisher: name: arXiv
Year: 2012
Subjects: subject: Dynamical Systems (math.DS)
subject: Functional Analysis (math.FA)
subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 37A30, 03F60

description: Let B be a p-uniformly convex Banach space, with p >= 2. Let T be a linear operator on B, and let A_n x denote the ergodic average (1 / n) sum_{i< n} T^n x. We prove the following variational inequality in the case where T is power bounded from above and below: for any increasing sequence (t_k)_{k in N} of natural numbers we have sum_k || A_{t_{k+1}} x - A_{t_k} x ||^p <= C || x ||^p, where the constant C depends only on p and the modulus of uniform convexity. For T a nonexpansive operator, we obtain a weaker bound on the number of epsilon-fluctuations in the sequence. We clarify the relationship between bounds on the number of epsilon-fluctuations in a sequence and bounds on the rate of metastability, and provide lower bounds on the rate of metastability that show that our main result is sharp.
Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome in patient with heart failure
Creators: name: Feige, Hellen
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Das Ziel der vorliegenden systematischen Übersichtsarbeit ist es, die existierende Evidenz der positiv inotrope und vasodilatative Therapieoptionen bei Kardiogenem Schock und Low Cardiac Output Syndrom bedingt durch Herzinsuffizienz zu sammeln, zusammenzufassen und zu bewerten. In den ausgewerteten Studien wurde die Wirksamkeit der Medikamente Levosimendan, Dobutamin, PGE1, Enoximon, Adrenalin, Noradrenalin, Milrinon und Dopamin in der beschriebenen Patientengruppe miteinander verglichen. Es konnte in keinem der Vergleiche eine statistisch signifikante Reduktion der Mortalität gezeigt werden. In Metaanalyen von fünf Studien, zeigte Levosimendan einen positiven Trend mit einer Reduktion der Mortalität im Vergleich zu den Kontrollgruppen ohne statistische Signifikanz zu erreichen. Größere Placebo-kontrollierte Studien werden benötigt, um den tatsächlichen Effekt von Levosimendan in Patienten mit Herzinsuffizienz und kardiogenem Schock oder Low Cardiac Output Syndrom zu bestätigen.
description: The objective of this systematic review is to collect the existing evidence for positive inotropic and vasodilative therapeutic strategies in case of cardiogenic shock and low cardiac output syndrome due to heart failure and to summarise and evaluate the results. The included studies investigated the efficacy of the drugs levosimendan, dobutamine, PGE1, enoximone, epinephrine, norepinephrine, milrinone and dopamine. No statistically significant reduction of mortality for any of the included drugs could be shown. In a meta-analysis of five studies, levosimendan showed a positive trend with a reduction in mortality compared to the different control groups not reaching statistical significance. Larger placebo-controlled trials are needed to evaluate the true effect of levosimendan in patients with HF.
Poincare-Einstein Holography for Forms via Conformal Geometry in the Bulk
Creators: name: Gover, A. Rod
name: Latini, Emanuele
name: Waldron, Andrew
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 53A30, 53B50, 53A55, 53B15, 22E46

description: We study higher form Proca equations on Einstein manifolds with boundary data along conformal infinity. We solve these Laplace-type boundary problems formally, and to all orders, by constructing an operator which projects arbitrary forms to solutions. We also develop a product formula for solving these asymptotic problems in general. The central tools of our approach are (i) the conformal geometry of differential forms and the associated exterior tractor calculus, and (ii) a generalised notion of scale which encodes the connection between the underlying geometry and its boundary. The latter also controls the breaking of conformal invariance in a very strict way by coupling conformally invariant equations to the scale tractor associated with the generalised scale. From this, we obtain a map from existing solutions to new ones that exchanges Dirichlet and Neumann boundary conditions. Together, the scale tractor and exterior structure extend the solution generating algebra of [31] to a conformally invariant, Poincare--Einstein calculus on (tractor) differential forms. This calculus leads to explicit holographic formulae for all the higher order conformal operators on weighted differential forms, differential complexes, and Q-operators of [9]. This complements the results of Aubry and Guillarmou [3] where associated conformal harmonic spaces parametrise smooth solutions.
description: 85 pages, LaTeX, typos corrected, references added, to appear in Memoirs of the AMS
Why Probability appears in Quantum Mechanics
Creators: name: Blackman, Jerome
name: Hsiang, Wu-Teh
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Early in the development of quantum theory Bohr introduced what came to be called the Copenhagen interpretation. Specifically, the square of the absolute value of the wave function was to be used as a probability density. There followed lengthy arguments about this ranging from alternative universes to Schrödinger's cat. Einstein famously remarked "I am convinced that He (God) does not play dice." The purpose of this paper is to present a mathematical model of the measuring process that shows that the Copenhagen interpretation can actually follow from the fact that the time development of quantum systems is governed by the usual one parameter group of unitary transformations exp(iHt) and that probability enters into the theory in the way it usually does in physics, namely, by having a large number of deterministic equations that can only be handled probabilistically
description: This paper has been accepted for publication in the March 2013 issue of Physics Essays
On the Question of Effective Sample Size in Network Modeling: An Asymptotic Inquiry
Creators: name: Krivitsky, Pavel N.
name: Kolaczyk, Eric D.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistics Theory (math.ST)
subject: Methodology (stat.ME)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: The modeling and analysis of networks and network data has seen an explosion of interest in recent years and represents an exciting direction for potential growth in statistics. Despite the already substantial amount of work done in this area to date by researchers from various disciplines, however, there remain many questions of a decidedly foundational nature - natural analogues of standard questions already posed and addressed in more classical areas of statistics - that have yet to even be posed, much less addressed. Here we raise and consider one such question in connection with network modeling. Specifically, we ask, "Given an observed network, what is the sample size?" Using simple, illustrative examples from the class of exponential random graph models, we show that the answer to this question can very much depend on basic properties of the networks expected under the model, as the number of vertices $n_V$ in the network grows. In particular, adopting the (asymptotic) scaling of the variance of the maximum likelihood parameter estimates as a notion of effective sample size ($n_{\mathrm{eff}}$), we show that when modeling the overall propensity to have ties and the propensity to reciprocate ties, whether the networks are sparse or not under the model (i.e., having a constant or an increasing number of ties per vertex, respectively) is sufficient to yield an order of magnitude difference in $n_{\mathrm{eff}}$, from $O(n_V)$ to $O(n^2_V)$. In addition, we report simulation study results that suggest similar properties for models for triadic (friend-of-a-friend) effects. We then explore some practical implications of this result, using both simulation and data on food-sharing from Lamalera, Indonesia.
description: Published at http://dx.doi.org/10.1214/14-STS502 in the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Why is satellite remote sensing of Sea-Surface Temperature important for climate monitoring and modelling?
Creators: name: O'Carroll Anne
Publisher: name: Zenodo
Year: 2021

description: UN Ocean Decade Satellite Event 16 September 2021: Ocean predictions and observations in response to the climate emergency
description: THE GHRSST PROJECT OFFICE IS FUNDED BY THE EUROPEAN UNION'S COPERNICUS PROGRAMME www.ghrsst.org
Adventures in Invariant Theory
Creators: name: Jarvis, P. D.
name: Sumner, J. G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Group Theory (math.GR)
subject: Statistics Theory (math.ST)
subject: Populations and Evolution (q-bio.PE)
subject: Quantum Physics (quant-ph)
subject: FOS: Biological sciences
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We provide an introduction to enumerating and constructing invariants of group representations via character methods. The problem is contextualised via two case studies arising from our recent work: entanglement measures, for characterising the structure of state spaces for composite quantum systems; and Markov invariants, a robust alternative to parameter-estimation intensive methods of statistical inference in molecular phylogenetics.
description: 12 pp, includes supplementary discussion of examples
Microstructural enrichment functions based on stochastic Wang tilings
Creators: name: Novák, J.
name: Kučerová, A.
name: Zeman, J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: This paper presents an approach to constructing microstructural enrichment functions to local fields in non-periodic heterogeneous materials with applications in Partition of Unity and Hybrid Finite Element schemes. It is based on a concept of aperiodic tilings by the Wang tiles, designed to produce microstructures morphologically similar to original media and enrichment functions that satisfy the underlying governing equations. An appealing feature of this approach is that the enrichment functions are defined only on a small set of square tiles and extended to larger domains by an inexpensive stochastic tiling algorithm in a non-periodic manner. Feasibility of the proposed methodology is demonstrated on constructions of stress enrichment functions for two-dimensional mono-disperse particulate media.
description: 27 pages, 12 figures; v2: completely re-written after the first review
Synthese von spezifisch deuterierten und undeuterierten Ceramiden des Dihydrosphingosins, Sphingosins und Phytosphingosins sowie eines spezifisch deuterierten Isopropylmyristats
Creators: name: Lange, Stefan
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: In dieser Arbeit wird zunächst die Synthese eines deuterierten Isopropylmyristats ausgehend vom D25-Bromdodecan und Acetamidomalonsäurediethylester beschrieben. Weiterhin wird dann auf die Darstellung deuterierter Grundkörper für die spätere Ceramidsynthese wie verschiedener racemischer α-Hydroxyfettsäuren, und einer 30-{[(10RS)-D33-10-Methylhexadecanoyl]oxy}triacontansäure eingegangen. Es wird zudem eine Synthesestrategie zur Darstellung der 30,30-D2-30-(Linoleoyloxy)triacontansäure vorgestellt. Die Ceramidkupplung zur Synthese von Ceramiden des Dihydrosphingosin-, Sphingosin- und Phytosphingosin-Typs erfolgte unter Verwendung von PyBOP. Weiterhin wird eine Methode zur Darstellung langkettiger perdeuterierter Carbonsäuren mittels D2O, KOH und Pd/C (10 %) im Autoklaven und die Diastereomerentrennung racemischer Ceramide mittels Säulenchromatographie aufgezeigt.
description: In this work, the synthesis of a deuterated isopropyl myristate starting from d25-bromododecane and diethylacetamidomalonate is described. Furthermore, the preparation of deuterated basic bodies for subsequent ceramide synthesis such as various racemic α-hydroxyfattyacids, and a 30-{[(10RS)-d33-10-methylhexadecanoyl]oxy}triacontanoic acid is then discussed. A synthetic strategy for the preparation of the 30,30-d2-30-(linoleoyloxy)triacontanoicacid is also presented. Ceramide coupling for the synthesis of dihydrosphingosine-, sphingosine- and phytosphingosine-type ceramides was performed using PyBOP. Furthermore, a method for the preparation of long-chain perdeuterated carboxylicacids using D2O, KOH and Pd/C (10%) in autoclave and the separation of diastereomers of racemic ceramides by column chromatography are shown.
Modified Bosonic Gas Trapped in a Generic 3-dim Power Law Potential
Creators: name: Castellanos, E.
name: Laemmerzahl, C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Gases (cond-mat.quant-gas)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We analyze the consequences caused by an anomalous single-particle dispersion relation suggested in several quantum-gravity models, upon the thermodynamics of a Bose-Einstein condensate trapped in a generic 3-dimensional power-law potential. We prove that the condensation temperature is shifted as a consequence of such deformation and show that this fact could be used to provide bounds on the deformation parameters. Additionally, we show that the shift in the condensation temperature, described as a non-trivial function of the number of particles and the trap parameters, could be used as a criterion to analyze the effects caused by a deformed dispersion relation in weakly interacting systems and also in finite size systems.
description: arXiv admin note: substantial text overlap with arXiv:1202.3801
Allocating provincial CO2 quotas for the Chinese national carbon program
Creators: name: Jiang, Minxing
name: Zhu, Bangzhu
name: Chevallier, Julien
name: Xie, Rui
name: Jiang, Minxing
name: Zhu, Bangzhu
name: Chevallier, Julien
name: Xie, Rui
Publisher: name: Unknown
Year: 2018
Subjects: subject: Environmental Economics and Policy
subject: Chinese national carbon program
subject: CO2 quota allocation
subject: interprovincial differences
subject: marginal abatement cost

description: In order to improve the efficiency of climate change initiatives China launched its national carbon market in December 2017. Initial CO2 quota allocations are a matter of significant concern. How should we allocate CO2 emissions reduction responsibilities among Chinese provinces, assuming that provinces will not or cannot trade these responsibilities among themselves? In this paper, we allocate CO2 quota from the perspective of cost minimisation. First, we estimate the national CO2 marginal abatement cost (MAC) function and deduce the interprovincial MAC functions. Second, we build an allocation model with nonlinear programming for cost minimisation. Finally, we obtain the allocation results under the emissions reduction target by 2030. The results are as follows. (i) The national MAC was 134.3 Yuan/t (at the constant price of 1978) in 2011, with an overall upward trend from 1990 to 2011. (ii) The interprovincial MACs differ significantly and decline gradually from east to west. Hebei has the largest emissions reduction quota, and Shandong has the largest emissions quota by 2030. (iii) Compared with other criteria of per capita, gross domestic product (GDP), grandfathering and carbon intensity, the proposed approach is the most cost-effective in achieving the reduction target, with cost savings of 37.7, 34.5, 47.9 and 33.87 per cent, respectively.
Consensus over Random Graph Processes: Network Borel-Cantelli Lemmas for Almost Sure Convergence
Creators: name: Shi, Guodong
name: Anderson, Brian D. O.
name: Johansson, Karl Henrik
Publisher: name: arXiv
Year: 2011
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: Distributed consensus computation over random graph processes is considered. The random graph process is defined as a sequence of random variables which take values from the set of all possible digraphs over the node set. At each time step, every node updates its state based on a Bernoulli trial, independent in time and among different nodes: either averaging among the neighbor set generated by the random graph, or sticking with its current state. Connectivity-independence and arc-independence are introduced to capture the fundamental influence of the random graphs on the consensus convergence. Necessary and/or sufficient conditions are presented on the success probabilities of the Bernoulli trials for the network to reach a global almost sure consensus, with some sharp threshold established revealing a consensus zero-one law. Convergence rates are established by lower and upper bounds of the $ε$-computation time. We also generalize the concepts of connectivity/arc independence to their analogues from the $*$-mixing point of view, so that our results apply to a very wide class of graphical models, including the majority of random graph models in the literature, e.g., Erdős-Rényi, gossiping, and Markovian random graphs. We show that under $*$-mixing, our convergence analysis continues to hold and the corresponding almost sure consensus conditions are established. Finally, we further investigate almost sure finite-time convergence of random gossiping algorithms, and prove that the Bernoulli trials play a key role in ensuring finite-time convergence. These results add to the understanding of the interplay between random graphs, random computations, and convergence probability for distributed information processing.
description: IEEE Transactions on Information Theory, In Press
An exact quantification of backreaction in relativistic cosmology
Creators: name: Clifton, Timothy
name: Rosquist, Kjell
name: Tavakol, Reza
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: An important open question in cosmology is the degree to which the Friedmann-Lemaitre-Robertson-Walker (FLRW) solutions of Einstein's equations are able to model the large-scale behaviour of the locally inhomogeneous observable universe. We investigate this problem by considering a range of exact n-body solutions of Einstein's constraint equations. These solutions contain discrete masses, and so allow arbitrarily large density contrasts to be modelled. We restrict our study to regularly arranged distributions of masses in topological 3-spheres. This has the benefit of allowing straightforward comparisons to be made with FLRW solutions, as both spacetimes admit a discrete group of symmetries. It also provides a time-symmetric hypersurface at the moment of maximum expansion that allows the constraint equations to be solved exactly. We find that when all the mass in the universe is condensed into a small number of objects (<10) then the amount of backreaction in dust models can be large, with O(1) deviations from the predictions of the corresponding FLRW solutions. When the number of masses is large (>100), however, then our measures of backreaction become small (<1%). This result does not rely on any averaging procedures, which are notoriously hard to define uniquely in general relativity, and so provides (to the best of our knowledge) the first exact and unambiguous demonstration of backreaction in general relativistic cosmological modelling. Discrete models such as these can therefore be used as laboratories to test ideas about backreaction that could be applied in more complicated and realistic settings.
description: 13 pages, 9 figures. Corrections made to Tables IV and V
Group schemes of period 2
Creators: name: Abrashkin, Victor
Publisher: name: arXiv
Year: 2011
Subjects: subject: Number Theory (math.NT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 11S20, 14K10

description: We give an explicit construction of the antiequivalence of the category of finite flat commutative group schemes of period 2 defined over the valuation ring of a 2-adic field with algebraically closed residue field. This result extends the earlier author's approach to group schemes of period p>2 from Proceedings of LMS, 101, 2010, 207-259.
description: 36 pages
Development and application of a molecular marker resource for improving drought stress tolerance in rye (Secale cereale L.)
Creators: name: Enders, Matthias
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2021
Subjects: subject: 630

description: Roggen (Secale cereale L.) ist ein wichtiges Getreide in Nordeuropa und hat eine herausragende Toleranz gegenüber biotischem- und abiotischem Stress, insbesondere auch Trockenstress. Um entsprechende Gene zu identifizieren und zu kartieren, wurde eine Transkriptomanalyse und eine in silico Kartierung durchgeführt. Zwei Eliteinzuchtlinien wurden einem kontrolliertem Trockenstress ausgesetzt und eine RNA Sequenzierung zweier Gewebetypen durchgeführt, sodass 128.010 contigs erzeugt werden konnten. Die Genexpression wurde für 47.842 Transkripte bestimmt. Zusätzlich konnten 19.826 Einzelnukleotid-Polymorphismen in 4.437 differenziell exprimierten Genen detektiert werden. Die chromosomale Lokalisation von 2.869 Transkripten wurde vorhergesagt. Um diese Daten zu evaluieren, wurde eine bi-parentale Population genotypisiert und phenotypisiert, eine genetische Kopplungskarte errechnet und eine QTL Kartierung durchgeführt, um den Wert der neuen Datenressource zu demonstrieren.
description: Rye (Secale cereale L.) is an important cereal crop in Northern Europe and known for its outstanding tolerance to biotic and abiotic stress including drought. To identify and map respective genes, a transcription profiling combined with an in silico mapping of drought-regulated transcripts was performed. Two elite inbred lines were exposed to drought under controlled conditions. RNA-seq was performed on leaves and a bulk comprising flag leaves, ears and shoots, respectively, resulting in 128,010 contigs. Gene expression was quantified for 47,842 transcripts with respect to drought treatment, genotype, and tissue. In addition, 19,826 single nucleotide polymorphisms were detected in 4,437 of the differentially expressed genes. The chromosomal location of 2,869 transcripts was predicted. To evaluate the data a bi-parental population was genotyped and phenotyped. Subsequently a genetic map was built, and a QTL mapping conducted to prove the value of the newly developed resource.
title:  Le possibilità della libertà. Valore, storia e famiglia nel pensiero di Jean-Paul Sartre
Creators: name: Adinolfi , Ciro
name: Meletti Bertolini  , Mara
Publisher: name: RomaTrE-Press
Year: 2023

description: Studi Sartriani – XVII/2023 – L’essere e il nulla. L’esistenzialismo di Sartre 80 anni dopo
Physikochemische Charakterisierung des Bindungsverhaltens des Histidin- und Prolinreichen Glykoproteins
Creators: name: Kampe, Melanie
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 540

description: Im Rahmen dieser Dissertation wurde das Bindungsverhalten des Histidin- und Prolinreichen Glykoproteins (HPRG) mit verschiedenen Liganden spektroskopisch untersucht. Im ersten Teil der Arbeit wurde dazu eine Aufreinigungsmethode etabliert, welche das Protein aus Kaninchenserum mit Hilfe einer Affinitäts- und einer Kationenaustauschchromatographie isolierte. Anschließend konnte EPR-spektroskopisch die Bindung mit nitroxidbasierten Liganden erfolgen. Weiterhin wurde Kupfer(II) genutzt, um daraus einen Einblick in die Koordinationssphäre und die bindenden Aminosäuren zu erhalten. Diese Messungen wurden sowohl unter verschiedenen Bedingungen, wie pH-Wert oder Stöchiometrie, als auch im Vergleich mit ausgewählten Peptidstrukturen des Proteins durchgeführt. Ebenfalls wurde in der Arbeit gezeigt, dass es möglich ist, die Selbstoxidation des Proteins EPR-spektroskopisch zu verfolgen. Durch gezielte qualitative Reaktionsbedingungen konnte die Oxidation des Proteins näher charakterisiert werden.
description: In this dissertation, the binding behavior of the histidine- and proline-rich glycoprotein (HPRG) with different ligands was investigated spectroscopically. In the first part of the thesis, a purification method was established for this purpose, which isolated the protein from rabbit serum using affinity and cation exchange chromatography. Subsequently, EPR spectroscopic binding with nitroxide-based ligands could be performed. Furthermore, copper(II) was used to gain insight into the coordination sphere and the binding amino acids from this. These measurements were performed under different conditions, such as pH or stoichiometry, as well as in comparison with selected peptide structures of the protein. Additionally, it is shown in the thesis that it is possible to follow the self-oxidation of the protein EPR spectroscopically. By using specific qualitative reaction conditions, the oxidation of the protein could be characterized in more detail.
Analyse der epidermal-growth-factor-receptor-mutierten Patienten von 2010-2015 des Lungenkrebszentrums Martha-Maria Halle-Dölau
Creators: name: Kassik, Ann-Cathleen
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Das Ziel dieser Arbeit ist es, die Wirksamkeit einer Tyrosinkinaseinhibitortherapie als Erst- und Zweitlinientherapie bei unterschiedlichen Patientengruppen mit einem fortgeschrittenem nicht-kleinzelligen Bronchialkarzinom und einer nachgewiesenen EGFR-Mutation zu vergleichen. Dabei wird ein besonderes Augenmerk auf die mediane Überlebenszeit und das mediane progressionsfreie Überleben gelegt. Als Tyrosinkinaseinhibitoren (TKI) wurden Erlotinib, Gefitinib und/oder Afatinib verwendet. Bei Patienten mit einer TKI-Zweitlinienbehandlung erfolgte zuvor eine Chemotherapie. Insgesamt wurden die Überlebensdaten von 36 Patienten verglichen. Es konnte ein Vorteil für Patienten mit einer TKI-Erstlinientherapie gegenüber von Patienten mit einer TKI-Zweitlinientherapie beobachtet werden. Weiterhin gibt es verschiedene positive prätherapeutische Prognosefaktoren, die bei der Wahl der Therapielinie berücksichtigt werden sollten und auch in der vorliegenden Analyse betrachtet wurden.
description: This work aims to compare the efficacy of tyrosine kinase inhibitor therapy as first- and second-line therapy in different groups of patients with advanced non-small cell lung cancer and a proven EGFR mutation. It pays particular attention to median survival and median progression-free survival. The tyrosine kinase inhibitors (TKIs) used were erlotinib, gefitinib and/or afatinib. Patients with second-line TKI treatment had a prior chemotherapy. Survival data from 36 patients was compared. An advantage was observed for patients with first-line TKI therapy compared to patients with second-line TKI therapy. Furthermore, there are several positive pretherapeutic prognostic factors that should be considered when choosing the line of therapy and were also examined in the present analysis.
Formation of helical ion chains
Creators: name: Nigmatullin, Ramil
name: del Campo, Adolfo
name: De Chiara, Gabriele
name: Morigi, Giovanna
name: Plenio, Martin B.
name: Retzker, Alex
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the nonequilibrium dynamics of the linear to zigzag structural phase transition exhibited by an ion chain confined in a trap with periodic boundary conditions. The transition is driven by reducing the transverse confinement at a finite quench rate, which can be accurately controlled. This results in the formation of zigzag domains oriented along different transverse planes. The twists between different domains can be stabilized by the topology of the trap and under laser cooling the system has a chance to relax to a helical chain with nonzero winding number. Molecular dynamics simulations are used to obtain a large sample of possible trajectories for different quench rates. The scaling of the average winding number with different quench rates is compared to the prediction of the Kibble-Zurek theory, and a good quantitative agreement is found.
Charakterisierung und Beurteilung von natürlichen Phospholipiden als Emulgatoren
Creators: name: Otto, Felix
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Natürliche Phospholipide (PL) sind eine native Alternative zu synthetischen Emulgatoren. Ein bekannter PL-haltiger Emulgator ist Lecithin, das hauptsächlich Phosphatidylcholin (PC) enthält und anderer PLs in Abhängigkeit von der Ausgangssubstanz. Ziel der vorliegenden Arbeit ist eine systematische Charakterisierung von natürlichen PLs unterschiedlicher Reinheitsgrade und Quellen mit dem Ziel den Einsatzbereich der PLs für Emulsionen zu beleuchten. Um dies zu bewerten, wurden HLB-Werte von vierzehn verschiedenen natürlichen PLs mit unterschiedlichem PC-Gehalt bestimmt. Per Kleinwinkelröntgenbeugung und Oberflächen-Druck Isothermen wurde die Struktur der Phospholipid-Membranen analysiert. Um die Charakterisierung auf ihre praktische Übertragbarkeit zu verifizieren, wurden Emulsionen aus natürlichen PLs untersucht. Für die Auswertung der mikroskopischen Aufnahmen wurde eine geeignete Bild-Analyse Methode entwickelt. Die Daten wurden per Histogramm verglichen und ausgewertet.
description: Natürliche Phospholipide (PL) sind eine native Alternative zu synthetischen Emulgatoren. Ein bekannter PL-haltiger Emulgator ist Lecithin, das hauptsächlich Phosphatidylcholin (PC) enthält und anderer PLs in Abhängigkeit von der Ausgangssubstanz. Ziel der vorliegenden Arbeit ist eine systematische Charakterisierung von natürlichen PLs unterschiedlicher Reinheitsgrade und Quellen mit dem Ziel den Einsatzbereich der PLs für Emulsionen zu beleuchten. Um dies zu bewerten, wurden HLB-Werte von vierzehn verschiedenen natürlichen PLs mit unterschiedlichem PC-Gehalt bestimmt. Per Kleinwinkelröntgenbeugung und Oberflächen-Druck Isothermen wurde die Struktur der Phospholipid-Membranen analysiert. Um die Charakterisierung auf ihre praktische Übertragbarkeit zu verifizieren, wurden Emulsionen aus natürlichen PLs untersucht. Für die Auswertung der mikroskopischen Aufnahmen wurde eine geeignete Bild-Analyse Methode entwickelt. Die Daten wurden per Histogramm verglichen und ausgewertet.
Low consistency refining of mechanical pulp : the relationship between plate pattern, operational variables and pulp properties
Creators: name: Elahimehr, Ali
Publisher: name: University of British Columbia
Year: 2014

description: In this dissertation we propose a framework to predict pulp properties of mean fibre length and freeness from low consistency (LC) refiner operating conditions and present correlations between those properties of pulp and hand sheet paper properties of tear, tensile and bulk. This framework is not new and was proposed by Luukkonen [1] however, studying the effect of plate pattern in this work based on the methodology presented in this dissertation is a novel approach. We accomplish this objective through the introduction of two geometrical parameters: Bar Interaction Length, BIL, and Bar Interaction Area, BIA. To do so, a comprehensive modelling of the geometry of disc refiner plates used in LC refining of mechanical pulp is done. We develop analytical and numerical models to estimate important geometrical parameters such as bar crossing area, leading edges of bar crossings and number of crossing points in a disc refiner with parallel distribution of bars. We will then use these models to predict pulp properties of mean fibre length and freeness from refiner operating conditions by running pilotscale refining trials of mechanical pulp over a wide range of plate pattern, rotational speed and gap size. From this stage, we present correlations between hand sheet paper properties of tear, tensile, bulk and pulp properties of freeness and fibre length. We also demonstrate a relationship between net power, plate pattern and refiner operating parameters such as plate gap and rotational speed based upon a classical dimensional analysis in which a reduced parameter space is related to each other through the use of statistical modelling.
Varying coefficient models as Mixed Models : reparametrization methods and bayesian estimation
Creators: name: Freni Sterrantino, Anna
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2013
Subjects: SECS-S/01 Statistica

description: Non-linear relationships are accommodated in a regression  model using smoothing functions. Interaction may occurs between continuous variable, in this case interaction between nonlinear and linear covariate leads to varying coefficent model (VCM), a subclass of generalized additive model. Additive models can be estimated as generalized linear mixed models, after being reparametrized. In this article we show three different type of matrix design for mixed model for VCM, by applying b-spline smoothing functions. An application on real data is provided and model estimates re computed with a Bayesian approach.
Nonverbales Verhalten von (Fußball-)trainern während des Wettkampfes und dessen potentielle Konsequenzen
Creators: name: Thrien, Fanny
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 155

description: Ziel der Arbeit ist die Untersuchung des kommunikativen Inhalts nonverbaler Äußerungen von Fußballtrainern während eines Spiels. Studie 1 (N = 152) und 2 (N = 50) zeigen, dass Personen anhand des NVV von Fußballtrainern im Spiel Rückschlüsse auf den Spielstand ziehen, ohne diesen zu kennen. Zudem bilden sich Personen anhand spezifischer nonverbaler Äußerungen von Fußballtrainern Inferenzen über deren Coachingkompetenz. Die Ergebnisse der dritten Untersuchung (N = 60) liefern Hinweise darüber, dass der nonverbale Lächelausdruck von Trainern unterschiedliche physiologische Stressreaktionen und subjektive Stimmungen bei den Athlet*innen in Abhängigkeit von der sozialen Bedeutung des Lächelausdrucks auslöst. Die praktischen Implikationen der Ergebnisse in Bezug auf das NVV von Trainern und die potenziellen Auswirkungen auf Athlet*innen werden diskutiert.
description: The aim of this paper is to investigate the communicative content of nonverbal expressions of soccer coaches during a match. Study 1 (N = 152) and 2 (N = 50) indicates that participants form inferences about the score based on the nonverbal behavior of soccer coaches during a game without knowing the score. In addition, individuals form inferences about soccer coaches' coaching competence based on soccer coaches' specific nonverbal expressions. The results of the third study (N = 60) provide evidence that coaches' nonverbal smile expressions elicit different physiological stress responses and moods in athletes depending on the social meaning of the smile expression. The practical implications of the findings regarding the body language of coaches and their potential impact on athletes are discussed.
On martingale approximations and the quenched weak invariance principle
Creators: name: Cuny, Christophe
name: Merlevède, Florence
Publisher: name: arXiv
Year: 2012
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: In this paper, we obtain sufficient conditions in terms of projective criteria under which the partial sums of a stationary process with values in ${\mathcal{H}}$ (a real and separable Hilbert space) admits an approximation, in ${\mathbb{L}}^p({\mathcal{H}})$, $p>1$, by a martingale with stationary differences, and we then estimate the error of approximation in ${\mathbb{L}}^p({\mathcal{H}})$. The results are exploited to further investigate the behavior of the partial sums. In particular we obtain new projective conditions concerning the Marcinkiewicz-Zygmund theorem, the moderate deviations principle and the rates in the central limit theorem in terms of Wasserstein distances. The conditions are well suited for a large variety of examples, including linear processes or various kinds of weak dependent or mixing processes. In addition, our approach suits well to investigate the quenched central limit theorem and its invariance principle via martingale approximation, and allows us to show that they hold under the so-called Maxwell-Woodroofe condition that is known to be optimal.
description: Published in at http://dx.doi.org/10.1214/13-AOP856 the Annals of Probability (http://www.imstat.org/aop/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Additional file 1 of Preoperative adjuvant therapy for locally advanced and recurrent/metastatic gastrointestinal stromal tumors: a retrospective study
Creators: name: Qi, Jing
name: Liu, He-Li
name: Ren, Feng
name: Liu, Sheng
name: Shi, Wei
name: Liu, Wei-Hang
name: Cai, Gao-Qiang
name: Liao, Guo-Qing
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy

description: Additional file 1: Table S1. Detail information of recurrent/metastatic GIST patients.
Guía del memorista de odontología de la Universidad de Talca
Creators: name: Rivera, César
Publisher: name: Zenodo
Year: 2019

description: Proyecto memoria es una disciplina semestral que tiene como prerrequisito el módulo de Odontología Poblacional. Para su realización dispone de 108 horas, correspondientes a 36 horas presenciales y 72 horas de trabajo autónomo orientado por un profesor guía. El módulo contribuye a la competencia número 12 del plan de formación de la carrera de Odontología de la Universidad de Talca: “Aplicar el método científico al estudio de problemas de salud identificados a nivel colectivo o  individual,  con  el  fin  de  contribuir  a  mejorar  la  calidad  de  vida  de  las  personas”. El proyecto memoria tiene por objetivo proporcionar a los estudiantes conocimientos y destrezas necesarias para la conducción de la memoria.  Este texto presenta algunas directrices para instruir a estudiantes, profesores guía y directores de departamento en la obtención de los productos del módulo (año 2019). Además explora la información declarada en el Syllabus. Cada tópico en adelante es explicado con una extensión que no supera las 100 palabras.
description: Versión 2019
Large transverse momentum dilepton production in heavy ion collisions with two-photon processes
Creators: name: Fu, Yong-Ping
name: Li, Yun-De
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The cold component of large transverse momentum dilepton production via semi-coherent two-photon interaction is calculated. The cold contribution is essential to the dilepton spectra in the soft region for different mass bins. The results are compared with the PHENIX experimental data at RHIC, and we find that the modification of semi-coherent two-photon processes is more evident with the rising dilepton mass bins.
description: 2 figures
Living together with our different belongings : philosophical roots, essentialist obstacles and intersectional alternatives
Creators: name: Uçar, Özgür
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 100

description: Das Hauptziel dieser Arbeit ist, die Ursprünge gesellschaftlicher Probleme in der Philosophiegeschichte bezüglich des Zugehörigkeitsbegriff sowie die Auswirkungen des essentialistischen Glaubenssystems auf diese Probleme zu untersuchen, und sich dadurch mit der Idee der dialogischen transversalen Politik und Intersektionalität auseinanderzusetzen, welche den mehrdimensionalen, dynamischen und intersektionalen Grundkonzept der Zugehörigkeit sichtbar macht. In dieser Hinsicht wurden diverse Merkmalen, die den Zugehörigkeitsbegriff gestalten, sowie die Unterscheidung zwischen dem Zugehörigkeitsbegriff und den Zugehörigkeitspolitiken untersuchet, deren Diskursstruktur durch die Mechanismen von dem essentialistischen Glaubenssystem ausgeprägt sind.
description: The main objective of this thesis is to examine the origins of social problems in the history of philosophy regarding the concept of belonging, as well as the impact of the essentialist belief system (EBS) on these problems, and thereby engage with the idea of dialogical transversal politics and intersectionality, which makes the multidimensional, the dynamic and intersectional basic concept of belonging visible. In this regard, diverse features that shape the concept of belonging, as well as the distinction between the concept of belonging and belonging politics, whose discourse structure is shaped by the mechanisms of the EBS, were examined. By conducting this research in the context of the idea of nationalism as a model of belonging policy, the impact of the EBS on our everyday life, our worldview, and thus our idea of belonging was presented.
Molekular- und strahlenbiologische Untersuchungen zur Wirkung von Betulinsäure und Betulin in humanen Glioblastomzelllinien unter normoxischen und hypoxischen Bedingungen
Creators: name: Zschornak, Martin Paul
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Das Glioblastom geht trotz multimodaler Therapie als aggressivster, primärer Hirntumor mit einer infausten Prognose einher. Betulinsäure (BS), ein Naturstoff aus der Birkenrinde, zeigt starken Einfluss auf zell- und strahlenbiologische Eigenschaften von Gliomzelllinien und kann Chemo- und Radioresistenz verbessern. BS zeigt eine erhöhte Zyototoxizität besonders unter hypoxischen Bedingungen. Dabei wird der mRNA- und Proteingehalt der Hypoxiemarker Hif-1α und CA-IX reduziert sowie der Proteingehalt des Apoptosemarkers gespaltenes PARP gesteigert und des Apoptoseinhibitors SVV vermindert. Zudem hemmt BS Migration und leitet Apoptose und Nekrose ein. In Kombination mit Bestrahlung treten unter normoxischen und hypoxischen Bedingungen in der Zelllinie U343MG additive und in der U251MG radiosensitivierende Effekte in Korrelation mit Effekten auf den Zellzyklus bei G2/M-Arrest unter Hypoxie auf. Die Muttersubstanz Betulin zeigt insgesamt geringer ausgeprägte Effekte. BS ist geeignet die Effekte einer Tumortherapie insbesondere in hypoxischen Tumoren zu verbessern.
description: Glioblastoma, as the most aggressive primary brain tumor, is associated with an inauspicious prognosis despite multimodal therapy. Betulinic acid (BS), a natural compound from birch bark, shows strong influence on cell and radiation biological properties of glioma cell lines and can improve chemo- and radioresistance. BS shows increased cyotoxicity especially under hypoxic conditions. In this context, the mRNA and protein levels of the hypoxia markers Hif-1α and CA-IX are reduced, and the protein level of the apoptosis marker cleaved PARP is increased and the apoptosis inhibitor SVV is decreased. In addition, BS inhibits migration and induces apoptosis and necrosis. In combination with irradiation, additive effects occur under normoxic and hypoxic conditions in cell line U343MG and radiosensitizing effects occur in U251MG in correlation with effects on the cell cycle upon G2/M arrest under hypoxia. The parent compound betulin shows less pronounced effects overall. BS is suitable to improve the effects of tumor therapy especially in hypoxic tumors.
The targum (1870:Oct.)
Creators: name: No Name Supplied
Publisher: name: Targum Association
Year: 1870

description: Some University historians indicate that the Targum was first published as an annual in 1867, but of this we have no extant evidence. In January 1869, the Targum as we now know it, made its appearance as a monthly paper that concerned itself with student “literary contributions” and college news as well as serving as a vehicle for bringing news to alumni and the general public. The newspaper, which originally was for sale, varied in frequency over the years as did its title (The Targum, Rutgers Targum, Rutgers Daily Targum, and Daily Targum). The newspaper has continuously been published since 1869 with the exception of 19 months during the second world war, between February 1944 and October 1945. The Targum was published by the students of Rutgers College, and later Rutgers University—New Brunswick represented through the years as the Targum Association, Rutgers Targum Association, and Rutgers College Targum. As a student organization, the Targum operated under the oversight of the dean of students and student government but in October 1980, the Targum became an independent college paper.