cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Interplay of strain, polarization and magnetic ordering in complex oxides from first principles
Creators: name: Eklund, Carl-Johan
Publisher: name: No Publisher Supplied
Year: 2010

description: We study mechanisms of structural and magnetic phase transitions in crystalline oxides from first principles. The focus is on epitaxial stabilization in perovskites and on magnetoelastic coupling and frustration in spinels. These materials and phenomena are of great interest for basic science and have important roles to play in the design and discovery of new functional materials. The effects of epitaxial strain on the structure of the perovskite oxide CaTiO3 are investigated. Particular attention is paid to the stabilization of a ferroelectric phase related to the polar instability found in previous first-principles studies of calcium titanate in the ideal cubic perovskite structure. At 1.5% strain, we find an epitaxial orientation transition between the ab-ePbnm phase, favoured for compressive strains, and the c-ePbnm phase. For larger tensile strains, a polar instability, which was hidden in the equilibrium bulk structure, develops in the c-ePbnm phase and an epitaxial-strain-induced ferroelectric phase is obtained with polarization along a [110] direction with respect to the primitive perovskite lattice vectors of the square substrate. A ferroelectric rhombohedral R3c phase, with a different combination of octahedral rotations, is also found to be competitive in energy for large tensile strains, and might be observable under the application of additional perturbations, such as a small degree of cation substitution. We present an ongoing project to construct a first-principles effective Hamiltonian to investigate the transition from the high-temperature cubic phase to a low-temperature low-symmetry phase observed in the spinel structure oxides CdCr2O4 and ZnCr2O4. The local modes included in the expansion are the chromium displacements, distortions of the cadmium- or zinc-centred tetrahedra, and the homogeneous strain. The magnetostructural coupling of these degrees of freedom to the spins of the chromium ions is included in the effective Hamiltonian parametrization and first-principles determination using a symmetry analysis. The role of the magnetostructural coupling in the phase transition is analysed and discussed.
Optimization models and algorithms for sample-preserved classification and clustering
Creators: name: Fan, Ya-Ju
Publisher: name: No Publisher Supplied
Year: 2010

description: This dissertation presents the development of new optimization models and algorithms for sample-preserved classification and clustering. A sample-preserved method keeps some or all of the existing samples when training a rule for classification or clustering, and continues to use them in the testing or predicting phase. Developing a sample-preserved method provides the capability of analyzing time series data due to the largely applied similarity measures on time series. A proposed sample-preserved classification technique, called Support Feature Machine (SFM), finds an optimal combination of features that gives the best classification based on the nearest neighbor rule. It keeps all baseline samples of the selected features in the predicting phase. Variations of SFM models are also presented. In addition, the bilinear program sample-preserved k-median (BPSPKM) clustering algorithm is introduced. While the original k-median problem can be solved by a simple and efficient bilinear program algorithm, it does not have the sample-preserved property, and only works with the 1-norm distance. The sample-preserved k-median (SPKM) clustering method is formulated as an integer programming problem, which is very hard to solve. A bilinear program algorithm is herein proposed in order to obtain local optimal solutions of the SPKM clustering method, as well as a new sequential search algorithm that can solve the SPKM clustering more efficiently. Finally, a novel feature space sample-preserved k-median (FSSPKM) clustering algorithm is proposed, as well as feature selection methods tailor made for such clustering technique. The experimental results show that the original k-median clustering fails to classify time series data due to the lack of the sample-preserved property, and the utilization of time series similarity measures. The sample-preserved medians can avoid having invalid values in some application domains and can be used to represent the samples in the clusters. The BPSPKM clustering algorithm with the Euclidean distance is suggested for clustering attribute (non-time series), univariate time series and multivariate time series data sets. Furthermore, the proposed feature selection methods consider the distances between cluster centers and cluster densities. The results show that the proposed algorithms outperform other feature selection techniques used in the original  k-median methods.
Barbus chonglingchungi Tchang 1936
Creators: name: Ye, Enqi
name: Xing, Yingchun
name: Zhang, Chunguang
name: Zhao, Yahui
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Cypriniformes
Cyprinidae
Barbus
Barbus chonglingchungi

description: Barbus chonglingchungi Tchang, 1936 (Fig. 7)
= Poropuntius chonglingchungi (Tchang, 1938)
Holotype. 0 3741 (10318), Jiangchuan County, Yunnan Province, P. R. China, Dec. 24, 1933. Paratypes. 0 3742 (10319), 0 3743 (10439), collected with holotype.
description: Published as part of Ye, Enqi, Xing, Yingchun, Zhang, Chunguang & Zhao, Yahui, 2015, Catalogue of the type specimens in the fish collection of the National Zoological Museum, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, pp. 10-113 in Zootaxa 3962 (1) on page 16, DOI: 10.11646/zootaxa.3962.1.4, http://zenodo.org/record/233837
Design and development of a pyrolysis probe for short path thermal desorption
Creators: name: Fan, Hao
Publisher: name: No Publisher Supplied
Year: 2010

description: Pyrolysis is the process of heating a substance to high temperature in the absence of oxygen so it does not burn but rather the thermal energy causes dissociation of chemical bonds. It has been widely employed as an analytical tool where it is combined with gas chromatography (GC) and its ancillary techniques (Mass Spectrometry, Fourier transform infrared spectroscopy, etc.). Analytical pyrolysis has been applied in a variety of areas such as microbial classification, protein identification, food packaging material identification, and forensics. State of the art commercial pyrolysis instruments have intrinsic disadvantages that undermine widespread application.  Most pyrolysis systems are dedicated attachments to a GC which preclude using the system for other injection techniques. Furthermore, commercial pyrolysis instruments are essentially probes inserted into the GC injector or are extensions to the GC injector. Pyrolysis releases high molecular weight, non-volatile residues into the GC injector which can foul the system and lead to sample to sample cross contamination problems.  The objective of this research is to design and develop a pyrolysis probe attachment for Short Path Thermal Desorption which would remedy the disadvantages of current commercial systems. Specifically, the new pyrolysis probe should combine the features of Short Path Thermal Desorption, have a quick setup, not be prone to injector contamination, be easily moveable and transferable, accurate and precise. A prototype has been built in our laboratory and subjected to mechanical and engineering tests. In the first demonstration of the new pyrolysis probe, virgin high density polyethylene (HDPE) was analyzed by pyrolysis-direct thermal desorption (DTD)-GC-MS. A very strong peak of ethylene (primary pyrolysis product) was evolved in the pyrogram followed by a homologous series of oligomers up to C40 thereby validating the instrument. Pyrolysis studies on other model polymers such as polystyrene (PS), ethylene vinyl alcohol (EVOH), ethylene vinyl acetate (EVA), and polyethylene terephthalate (PET) were also proved successful in revealing their monomers, oligomers, important decomposition products, and additives. The pyrolysis chamber and sample tube was very clean after each run and no cross contamination was detected between injections, proving the superiority of this novel pyrolysis system over existing commercial instruments.
Essays on business cycles in emerging economies
Creators: name: Fernandez Martin, Andres
Publisher: name: No Publisher Supplied
Year: 2010

description: The central goal of this dissertation is to contribute to the understanding of business cycles in developing economies by combining the use of general equilibrium modeling, time series analysis and historical evidence. The dissertation is made of three separate but related chapters. In the first chapter, I put to the test the two leading approaches for analyzing business cycles in emerging economies by building a model that combines stochastic trends, interest rate shocks and financial frictions. I then estimate the model using Bayesian methods and Mexican data from the 1980s. The results favor strong financial frictions, volatile shocks to the processes for interest rates and transient technology, and modest trend shocks. Financial frictions act as powerful amplifying mechanisms to interest rate and transient technology shocks. The results are thus supportive of the view that assuming foreign interest rate shocks in conjunction with financial imperfections is a superior approach to assuming stochastic trends if one is trying to explain fluctuations in emerging economies.  The second chapter presents an augmented model with two additional driving forces: terms of trade and government expenditure shocks. The model is estimated with Colombian data using both high frequency quarterly data and low frequency annual data. The results continue to suggest that financial frictions act as powerful amplifying mechanisms and that trend shocks are not relevant in explaining emerging market business cycles. Among the two new shocks added, just the terms of trade appear relevant and only in the low frequency data. The third chapter focuses on business cycles in emerging economies from a historical perspective. It is argued that the significant capital flows observed in Latin America during the 1920s and early 1930s offer a good historical experiment to study the transmission mechanism by which external shocks to capital markets turn into large capital flows and wider business cycles in developing economies. The chapter uses a framework that combines a historical account of the 1920s-1930s Latin American episode with a dynamic general equilibrium model aimed at explaining the dynamics observed in the data. The model does well in matching the expansionary/contractionary phases in output dynamics, in accordance with the main stylized facts observed in the business cycles in Latin American countries between 1925 and 1931.
Print and the cultures of criticism
Creators: name: Gavin, Michael
Publisher: name: No Publisher Supplied
Year: 2010

description: Print and the Cultures of Criticism reconsiders Restoration and eighteenth-century literary criticism as a material practice of writing and publication. In prefaces, pamphlets, libels, and mock-epics, poets used print as an instrument of literary rivalry and in theprocess gave shape to a cultural field of poetry and criticism. Through tracing their controversies, I revise the consensus view that early criticism disciplined readers with a disinterested discourse of polite taste. Rather, criticism was forged in a turbulent printmarketplace where authors’ commercial and political interests often collided with their intellectual and professional ambitions. Placing factionalism at the center of criticism’s history suggests that literary ideas proliferated through conflict and became mostpowerful when subject to the most vocal objection. My project focuses on moments of literary controversy to explore how printed disputes shifted as they moved across the still-fluid genres of critical writing. From 1660 to the first decades of the eighteenth century, sporadic debates between playwrights had evolved into a widely shared practice of literary rivalry. The success of John Dryden’s heroic dramas sparked heated debates over prosody and dramatic form: opinions came out in play performances, verse prologues and epilogues, prefatory essays, pamphlets, and eventually manuscript satires. By the turn of the century, poets, critics, playwrights, scholars, booksellers, and even readers were seen to engage in a special kind of combat—the mock-epic battles of “Parnassus”—that divided them into factions while binding them together in a common project of public dispute. I then turn to writers who, in very different ways, attempted to insulate poetry from the turmoil of literary factionalism. Anne Finch and Alexander Pope concluded that modern criticism had become irredeemably dysfunctional. Critics haunt their poems with ambient violence. Through these case studies, I argue against the prevailing notion that early criticism regulated culture while dictating to a passive readership of anonymous book-buyers. Taking abroader view that accounts for the wide range of genres at critics’ disposal suggests that few had the clout to impose their judgments and that literary value emerged most powerfully from below.
A multiscale model for the assessment of autonomic dysfunction in human endotoxemia
Creators: name: Foteinou, Panagiota
Publisher: name: No Publisher Supplied
Year: 2010

description: The overall goal of this dissertation is the development of a semi-mechanistic, physiology-based, multiscale model of human endotoxemia, as a prototype model of acute inflammation in humans that integrates essential regulatory processes across the host from the cellular to the systemic level. The complex and multiplex characteristics of the acute inflammatory response and its complications have been thought to be a leading potential reason for the inability to propose effective clinical intervention strategies. The nature of the response has led researchers to the realization that mathematical models of inflammation offer the opportunity to study the dynamics of interacting components and establish a causal inference relationship through the manipulation of the corresponding dynamic elements. Driven by the premise to develop in silico methodologies that will enable translational research to elucidate mechanisms by which macroscopic responses, at the physiome level, emerge as the result of propagating information across an intricate web of interacting modules, a systems-level modeling approach is developed that addresses the following unique aspects: (i) identification of the essential components characterizing cellular transcriptional dynamics in response to an external perturbation; (ii) reverse engineering of quantifiable representations of these elements exploring the concept of physicochemical and indirect response modeling that connect extracellular signals and intracellular signaling cascades leading to the emergent transcriptional dynamics; and finally (iii) multiscale, physiology-based modeling that quantifies critical aspects of the complex neuro-immune crosstalk while clinical observables are explicitly incorporated to assess systemic abnormalities indicative of the severity of the host.   It is therefore the purpose of this research to demonstrate the feasibility of a relevant human inflammation model that bridges the initiating signal and phenotypic expressions through semi-mechanistic based host response models that include transcriptional dynamics, signaling cascades and physiological components; and to define a notional template for multiscale modeling extendable to a wide range of clinically important conditions. The ultimate deliverable of the proposed research is the multiscale human inflammation model that would allow us to clarify the clinical contexts in which inflammatory dysregulation contributes to morbidity and mortality in acutely stressed patients; thereby advancing the translational potential of systems modeling in clinical research.
A spatial analysis of healthy food availability in urban neighborhoods
Creators: name: Guidry, Marilyn M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Food insecurity and poor access to healthy foods is a global and local issue. In the United States, urban populations demonstrate enormous disparities in quality and access to food resources necessary for a healthy life. This study demonstrates that although healthy foods may be available within a close proximity to some urban neighborhoods, these resources may be in limited supply or inaccessible by segments of local populations. In south and southwest Philadelphia, two neighborhoods demonstrate a high concentration of fresh food and vegetable availability characterized by supermarket service regions of approximately 0.10 square miles. Six additional high density neighborhoods demonstrate much lower availability with supermarket service regions extending to 2.53 square miles. Gaps or underserved areas outside supermarket service areas demonstrate a lower rate of accessibility to fresh fruit and vegetables than the corresponding service  iv  areas of supermarkets. Within supermarket service areas the density of grocers stocking fresh fruits and vegetables is 35.3 grocers per square mile. In supermarket gap areas this number drops to 7.1 grocers per square mile. Thus some neighborhoods have access not only to supermarkets, but also benefit from a higher density of smaller grocers stocking fresh fruits and vegetables. Similarly, the mean produce accessibility rate for pedestrian supermarket service areas is 887.3 square feet of fresh fruits and vegetables per 1000 population. The produce accessibility rate drops significantly in pedestrian and public transit gap areas. In spite of statistical relationships between produce accessibility and location in a gap or service area, fruit and vegetable intake does not show a correlation with an accessibility measure to supermarkets. Policy recommendations include aligning transportation and food access for underserved areas and coupling education with improved access to improve healthy food intake. Neighborhoods vulnerable to poor fresh fruit and vegetable access tend to be less dense fringe areas of well established urban neighborhoods.
Pitella Langer 1992
Creators: name: Mamo, Briony L.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Chromista
Foraminifera
Tubothalamea
Miliolida
Hauerinidae
Pitella

description: Pitella Langer 1992
Pitella haigi Langer 1992 (Fig. 7:5, 6)
Description. See Langer (1992, p. 91, pl. 2, figs 11–14).
Distribution within study area. This species was only recovered once at site 3 of Transect 2 from Heron Reef flat.
description: Published as part of Mamo, Briony L., 2016, Benthic Foraminifera from the Capricorn Group, Great Barrier Reef, Australia, pp. 1-123 in Zootaxa 4215 (1) on page 32, DOI: 10.11646/zootaxa.4215.1.1, http://zenodo.org/record/272923
Barbus huangchuchieni Tchang 1962
Creators: name: Ye, Enqi
name: Xing, Yingchun
name: Zhang, Chunguang
name: Zhao, Yahui
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Cypriniformes
Cyprinidae
Barbus
Barbus huangchuchieni

description: Barbus huangchuchieni Tchang, 1962 (Fig. 8)
= Poropuntius huangchuchieni (Tchang, 1962)
Holotype. 39258 (56.4.17), Mengla County, Xishuangbanna State, Yunnan Province, P. R. China, Apr. 17, 1956. Paratypes. 39256 (56.4.17), collected with holotype; 42865 (1903), locality with holotype, Apr. 28, 1956.
description: Published as part of Ye, Enqi, Xing, Yingchun, Zhang, Chunguang & Zhao, Yahui, 2015, Catalogue of the type specimens in the fish collection of the National Zoological Museum, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, pp. 10-113 in Zootaxa 3962 (1) on page 17, DOI: 10.11646/zootaxa.3962.1.4, http://zenodo.org/record/233837
Determination of structural changes and phase transformations in boron carbide by static and dynamic studies
Creators: name: Gupta, Varun
Publisher: name: No Publisher Supplied
Year: 2010

description: Recent transmission electron microscopy results demonstrate that the failure of B4C is commensurate with the segregation of boron icosahedra embedded in amorphous carbon in 2–3 nm wide amorphous bands along the (113) lattice direction, in good agreement with our recent theoretical results. Boron carbide is generally composed of multiple polytypes of B4C which have the same primitive lattice parameters but differ from each other by the location of the boron and carbon atoms in the unit cells. The unit cells are formed by a 12-atom B12-nCn icosahedron and a 3-atom (C3-nBn) chain. Our theoretical results indicate that one polytype, B12(C3), whose formation is responsible forthe failure of the entire material. This anomalous and poorly understood glass-like behavior in boron carbide has been the subject of research since its discovery over 70 years ago. The characterization of disorder in hot pressed and powder boron carbide samplesis therefore of primary interest. The research work has focused on characterization techniques which can be used at a micrometric sampling size so that individual powder grains of the material can be utilized. Specifically, micro-Raman and electricalconductivity measurements can be used with micrometric gap cells to understand the disorder in B4C.The results also demonstrate that it is possible to induce transformations in boron carbide using electric fields that are comparable with those obtained under shock and nanoindentation. Our calculations present a hypothesis which can provide a solution to prevent thepremature failure of B4C. A route to achieve suppression of the B12(CCC) polytype without significantly affecting the elastic constants is via low concentration Silicon (Si) doping of B4C. Suppression of B12(CCC) by Si doping has implications towardsdevelopment of boron carbide armor with improved properties for protection against high velocity threats. In order to achieve this, nanostructures (nanowires, nanorods, etc.) of Sidoped boron carbide have been synthesized using a Solid-Liquid-Solid (SLS) growthmechanism. The resulting structures have been characterized by SEM, TEM and Ramanspectroscopy and consolidated to evaluate their mechanical properties. In addition, the application of nanowires in a transparent and thermally conducting nanocomposite is demonstrated.
Barbodes laticeps Lin & Zhang 1986
Creators: name: Ye, Enqi
name: Xing, Yingchun
name: Zhang, Chunguang
name: Zhao, Yahui
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Cypriniformes
Cyprinidae
Barbodes
Barbodes laticeps

description: Barbodes laticeps Lin & Zhang, 1986 (Fig. 9)
= Linichthys laticeps (Lin & Zhang), 1986
Paratype. 60796-60801, Guizhou Province; no date.
description: Published as part of Ye, Enqi, Xing, Yingchun, Zhang, Chunguang & Zhao, Yahui, 2015, Catalogue of the type specimens in the fish collection of the National Zoological Museum, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, pp. 10-113 in Zootaxa 3962 (1) on page 18, DOI: 10.11646/zootaxa.3962.1.4, http://zenodo.org/record/233837
The impact of affordable housing on taxable property valuation in a poor city
Creators: name: Harris, Gwendolyn
Publisher: name: No Publisher Supplied
Year: 2010

description: This research looks at the impact of affordable housing development on the tax base in a poor city. Viability of the tax base is a critical matter for municipalities to address as they plan revitalization strategies. Poor cities may include affordable housing development as a revitalization strategy to meet the needs of their housing cost burdened residents or to upgrade blighted or unproductive property. Prior research has looked at the impact of affordable housing on concerns such as concentration of poverty, crime, racial segregation, and resale value of nearby housing, but not tax base.      While preliminary bivariate findings indicated that taxable property value increased at a greater rate in the zone closest to affordable housing development, the results of the discriminant analysis found that affordable housing had a minimal influence on taxable property value change, and that other factors were better determinants of the change. Quantitative and qualitative results suggest that in addition to prior taxable property valuation, social fabric within the community before affordable housing development is a better predictor of the change in tax value of surrounding property.
Experimental modeling of focused shortening
Creators: name: Hidayah, Triyani
Publisher: name: No Publisher Supplied
Year: 2010

description: This thesis presents four series of sand and clay analogue models of compressional deformation: no erosion and sedimentation (S1), erosion (S2), sedimentation (S3s and S3c), and no erosion and sedimentation with an indentor (S4). All models produce a single fault zone, except S4 which produced multiple fault zones. The models show that erosion and sedimentation influence the major fault and fold geometries, fault displacement, ramp-dip angles, and the width of the deformation zones. The major faults in the models with low or no sedimentation (S1) and erosion (S2) have a flat-ramp-flat geometry. Erosion produces the narrowest deformation zone. In contrast, the sand model with sedimentation (S3s) has the widest deformation zone and the steepest ramp-dip angle; it lacks the upper flat section of the main thrust fault. Clay and sand models have similar large-scale deformation patterns. The models produce a series of backthrusts and an upward-widening main reverse fault zone. Steeply dipping to overturned beds and branching faults are present within the main fault zones. The clay models have narrower fault zones, more faults with smaller displacements, more blind faults, more folding, and steeper backthrusts than the sand model. Calculations for the sand and clay models show that the backthrusts and main thrust account for only 45-50% of the imposed shortening.  S4 provides insight on the patterns of secondary faulting that develop on the anticlines above the main thrust faults. Normal faults form parallel to the hinge line on the crest of the anticlines and perpendicular to the hinge line at the plunging ends of the anticlines where two offset anticlines propagated and merged together. Seismic data from areas of reverse/thrust faulting (e.g., offshore Nigeria) commonly contain no-record zones corresponding to the main reverse fault zone in the experimental models. The experimental models provide insight into the complex structures within these fault zones: steeply dipping to overturned beds and multiple branching faults.
First report of Candida auris in Guangdong, China: clinical and microbiological characteristics of 7 episodes of candidemia
Creators: name: Peng, Yaqin
name: Liu, Yue
name: Yu, Xuegao
name: Fang, Jingchun
name: Guo, Zhaowang
name: Liao, Kang
name: Chen, Peisong
name: Guo, Penghao
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Candida auris is an emerging multidrug-resistant fungal pathogen worldwide. To date, it has not been reported in Guangdong, China. For the first time, we reported 7 cases of C. auris candidemia from two hospitals in Guangdong. The clinical and microbiological characteristics of these cases were investigated carefully. Two geographic clades, i.e., III and I, were found popular in different hospitals by whole genome sequencing analyses. All C. auris isolates from bloodstream were resistant to fluconazole, 5 of which belonged to Clade III harboring VF125AL mutation in the ERG11 gene. The isolates with Clade I presented Y132F mutation in the ERG11 gene as well as resistance to amphotericin B. All isolates exhibited strong biofilm-forming capacity and non-aggregative phenotype. The mean time from admission to onset of C. auris candidemia was 39.4 days (range: 12 - 80 days). Despite performing appropriate therapeutic regimen, 42.9% (3/7) of patients experienced occurrences of C. auris candidemia and colonization after the first positive bloodstream. C. auris colonization was still observed after the first C. auris candidemia for 81 days in some patient. Microbiologic eradication from bloodstream was achieved in 85.7% (6/7) of patients at discharge. In conclusion, this study offers a crucial insight into unraveling the multiple origins of C. auris in Guangdong, highlighting great challenges in clinical prevention and control.
Chromosomal integration and plasmid fusion occurring in ST20 carbapenem-resistant Klebsiella pneumoniae isolates coharboring blaNDM-1 and blaIMP-4 induce resistance transmission and fitness variation
Creators: name: Shi, Qiucheng
name: Hu, Huangdu
name: Yu, Qian
name: Huang, Weiyi
name: Wang, Yinping
name: Quan, Jingjing
name: Zhou, Junxin
name: Weng, Rui
name: Zhang, Ping
name: Meng, Yan
name: Liu, Haiyang
name: Jiang, Yan
name: Yu, Yunsong
name: Du, Xiaoxing
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: To investigate the epidemiology of ST20 carbapenem-resistant Klebsiella pneumoniae (CRKP) in China, and further explore the genomic characteristics of blaIMP-4 and blaNDM-1 coharboring isolates and plasmid contributions to resistance and fitness. Seven ST20 CRKP isolates were collected nationwide, and antimicrobial susceptibility testing was performed. Antimicrobial resistance genes, virulence genes, and plasmid replicons were identified via whole-genome sequencing, and clonality assessed via core-genome multilocus sequence typing. Furthermore, we found four dual-metallo-β-lactamases (MBL)-harboring isolates, the gene location was detected by Southern blotting, and plasmid location analysis showed that blaIMP-4 was located on a separate plasmid, a self-conjugative fusion plasmid, or the bacterial chromosome. These isolates were subjected to long-read sequencing, the presence of blaIMP-4 in different locations was identified by genomic comparison, and transposon units were detected via inverse PCR. We subsequently found that blaIMP-4 on the fusion plasmid and bacterial chromosome was formed via intact plasmid recombination by the IS26 and ltrA, respectively, and the circular transposon unit was related to cointegration, however, blaIMP-4 in different locations did not affect the gene stability. The blaNDM-1-harboring plasmid contributed to the increased resistance to β-lactams and shortened survival lag time which was revealed in plasmid cured isolates. In summary, the K. pneumoniae ST20 clone is a high-risk resistant clone. With the use of ceftazidime/avibactam, MBL-positive isolates, especially dual-MBL-harboring isolates, should be given additional attention.
Additional file 1: of A randomised controlled trial assessing the severity and duration of depressive symptoms associated with a clinically significant response to sertraline versus placebo, in people presenting to primary care with depression (PANDA trial): study protocol for a randomised controlled trial
Creators: name: Salaminios, George
name: Duffy, Larisa
name: Ades, Anthony
name: Araya, Ricardo
name: Button, Katherine
name: Churchill, Rachel
name: Croudace, Tim
name: Derrick, Catherine
name: Padraig Dixon
name: Dowrick, Christopher
name: Gilbody, Simon
name: Hollingworth, William
name: Jones, Vivien
name: Kendrick, Tony
name: Kessler, David
name: Kounali, Daphne
name: Lanham, Paul
name: Malpass, Alice
name: Peters, Tim
name: Riozzie, Derek
name: Robinson, Jude
name: Sharp, Debbie
name: Thomas, Laura
name: Welton, Nicky
name: Wiles, Nicola
name: Lewis, Glyn
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 122 kb)
Welfare
Creators: name: McKinney, Jenna L.
Publisher: name: No Publisher Supplied
Year: 2010

description: There are great many things that Americans can truly claim as their own, welfare is one of them. Welfare has become and American staple that rivals fords and baseball. America has created an ideology that is both accepting and allowing of consumerism and inefficiency, when it comes to fiscal responsibility. Americans idealize capitalism and also charity work, causing a collision of ideas politically and socially. The allowance for both has brought on two schools of thought. In one school, we as a culture press for innovation and poise in society, in the other we see classes of people who are constantly behind the economical curve. As they have come to coexist, the principles of our society have learned to accept that some people will accelerate and others will struggle with assistance of the government. Welfare has become cyclical (from adult to child, and then to that child as an adult) because we as a culture accept that welfare exists through legislation, ideals and in the business sector. Welfare has become a truly American innovation, spreading, and expanding, creating an entire genre of social status. Welfare is an American staple because even though we as a culture recognize its continued presence, we have yet to understand it. Comprehensive approaches to both education and the dolling out of American tax dollars would correct and also alleviate the fiscal beating that we as a society experience, and also remove the stigma applied to welfare recipients.
Additional file 1: Table S1. of Biological function integrated prediction of severe radiographic progression in rheumatoid arthritis: a nested case control study
Creators: name: Joo, Young
name: Kim, Yul
name: Youngho Park
name: Kwangwoo Kim
name: Ryu, Jeong
name: Seunghun Lee
name: Bang, So-Young
name: Hye-Soon Lee
name: Gwan-Su Yi
name: Sang-Cheol Bae
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Characteristics of study populations. Table S2. GWAS results for severe radiographic progression (p <1.0 × 10–3). Table S3. List of the top 85 SNPs and their related genes selected by a post-GWAS approach. Table S4 Sensitivity, specificity, and positive predictive value of the final models. (DOCX 77 kb)
Barbus regani Tchang 1935
Creators: name: Ye, Enqi
name: Xing, Yingchun
name: Zhang, Chunguang
name: Zhao, Yahui
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Cypriniformes
Cyprinidae
Barbus
Barbus regani

description: Barbus regani Tchang, 1935 (Fig. 10)
= Percocypris regani (Tchang, 1935)
Holotype. 0 3682 (10393), Jiangchuan County, Yunnan Province, P. R. China, Dec. 24, 1933. Paratype. 0 3683 (10394), collected with holotype.
description: Published as part of Ye, Enqi, Xing, Yingchun, Zhang, Chunguang & Zhao, Yahui, 2015, Catalogue of the type specimens in the fish collection of the National Zoological Museum, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, pp. 10-113 in Zootaxa 3962 (1) on page 19, DOI: 10.11646/zootaxa.3962.1.4, http://zenodo.org/record/233837
Djeboa maromandia Pesic, Cook & Gerecke, sp. nov.
Creators: name: Pešić, Vladimir
name: Cook, David
name: Gerecke, Reinhard
name: Smit, Harry
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Mideopsidae
Djeboa
Djeboa maromandia

description: Djeboa maromandia Pešić, Cook & Gerecke sp. nov.
(Figs. 28A–F, 40C–D)
Type series: Holotype male, dissected and slide mounted, Madagascar 120d, Maromandia, River Andranamalaza, 70 m asl., 31.3 ˚C, 0.023 mS/cm, 21.x.2001, Gerecke & Goldschmidt. Paratype: same data as holotype, one male, dissected and slide mounted.
Diagnosis: Idiosoma anteriorly rounded; dorsal shield elliptical (L/W ratio 1.2), with little pronounced medial depression in the distal half (Figs. 40C–D), lateral ridges slightly elevated and size of body pores gradually diminuishing medially, the mounted specimen with an area of purple brownish colouration restricted to the anterior half of dorsal shield; muscle scars weakly pronounced, visible only as small granulated areas (Figs. 28D); gnathosomal bay Y-shaped; tips of Cx-I extending slightly beyond frontal margin; Cx-III and -IV with a few longitudinal striae (two pairs on Cx-IV). Palp (Figs. 28C–D): P-1 with a dorsal seta; P-2 with straight ventral and convexly bowed dorsal margin; P-3 with a basal kink, from here to distal edge straight; ventral margin of gnathosoma with a long, pointed projection (Fig. 28D, arrow). Legs: I-L (Fig. 28E) with I-L-5 rather stout, ventral margin forming an obtuse angle in proximal third; I-L-6 L/H ratio 2.2, ventral margin forming an obtuse angle proximally, in distal half convexly protruding; distal segments of IV-L: Fig. 27 F; swimming setae numbers: III-L- 4, 5; III-L-5, 4; IV-L-4, 4; IV-L-5, 7.
Description:
Male (holotype): Idiosoma (ventral view: Fig. 28B) L/W 444/389. Dorsal shield (Figs. 28A, 38C) L/W 370/ 300, L/W ratio 1.23; gnathosomal bay L 86. Gonopore L/W 85/23; ejaculatory complex L 152. Palp: total L 163- 167; L/H, L/H ratio: P-1, 20/23, 0.87; P-2, 43-46/37-38, 1.17-1.22; P-3, 39/25, 1.6; P-4, 47-48/18-19, 2.5-2.6; P-5, 14/8, 1.8; chelicera total L 100; gnathosoma vL 102. Legs: dL of I-L-3-6: 40, 42, 55, 74; I-L-6 H 33, L/H ratio 2.24.
Female: Unknown.
Etymology: Named after the area where it was collected.
Discussion: See discussion under Djeboa elephantina sp. nov.
Distribution: Madagascar; known only from type locality in forest remnants near the northwestern coast.
description: Published as part of Pešić, Vladimir, Cook, David, Gerecke, Reinhard & Smit, Harry, 2013, The water mite family Mideopsidae (Acari: Hydrachnidia): a contribution to the diversity in the Afrotropical region and taxonomic changes above species level, pp. 1-75 in Zootaxa 3720 (1) on page 49, DOI: 10.11646/zootaxa.3720.1.1, http://zenodo.org/record/285029
Long ignored but making a comeback: a worldwide epidemiological evolution of human brucellosis
Creators: name: Liu, Zhiguo
name: Gao, Liping
name: Wang, Miao
name: Yuan, Min
name: Li, Zhenjun
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Brucellosis is a commonly neglected zoonosis but remains a serious public health concern globally. The epidemiological evolution of human brucellosis has changed considerably over the past decades, and the epidemic geography is continuously expanding. Human brucellosis is increasingly emerging and re-emerging, imported from areas in which it is endemic due to travel, immigration, and international trade. The disease continues to be rampant in Asia and Africa, including West Asia, Central Asia, North Africa, and East Africa, with the highest incidences in Syria, Kyrgyzstan, Mongolia, Iran, Algeria, and Kenya. Re-emerging cases are frequently recorded in places where brucellosis has achieved control, such as Bosnia and Herzegovina, Azerbaijan, and USA. In countries with a high disease burden, control and eradication of the disease has been extremely difficult due to livestock farming as the only source of livelihood, unique religious beliefs regarding animals, a nomadic lifestyle, and low socioeconomic levels. Interventions focused on protecting livestock keepers are needed, particularly for those assisting with goat and sheep births and consumption of raw dairy products.⁣ Strikingly, in the majority of countries with a high disease burden, each period of several years with a low incidence rate was followed by a subsequent increase in cases, highlighting that continuous investment and surveillance are necessary. In addition, advocacy for the inclusion of brucellosis as a globally mandated reported disease, strict restrictions on animal movement, mandated consumption of pasteurized milk, and health education are needed. The present study will help in forming an evidence-based strategy for international organizations to curb the future spread of brucellosis.
Crossocheilus bamaensis Fang 1981
Creators: name: Ye, Enqi
name: Xing, Yingchun
name: Zhang, Chunguang
name: Zhao, Yahui
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Cypriniformes
Cyprinidae
Crossocheilus
Crossocheilus bamaensis

description: Crossocheilus bamaensis Fang, 1981 (Fig. 11)
= Sinocrossocheilus bamaensis (Fang, 1981)
Holotype. 60270 (743114), Hongshuihe River basin: Panyanghe River, Jiazhuan Community, Bama County, Guangxi Province, P. R. China, May 7, 1974.
Paratypes. 60271 (743117), 60272 (743125), 60273-4 (743134-743135), collected with holotype; 60275 (76074), 60276 (76075), 60277(76083), 60278(76105), 60279 (76076), 60280 (76112), locality with holotype, Oct. 17, 1976.
description: Published as part of Ye, Enqi, Xing, Yingchun, Zhang, Chunguang & Zhao, Yahui, 2015, Catalogue of the type specimens in the fish collection of the National Zoological Museum, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, pp. 10-113 in Zootaxa 3962 (1) on page 20, DOI: 10.11646/zootaxa.3962.1.4, http://zenodo.org/record/233837
The impact of S2 mutations on Omicron SARS-CoV-2 cell surface expression and fusogenicity
Creators: name: Escalera, Alba
name: Laporte, Manon
name: Turner, Sam
name: Karakus, Umut
name: Gonzalez-Reiche, Ana S.
name: van de Guchte, Adriana
name: Farrugia, Keith
name: Khalil, Zain
name: van Bakel, Harm
name: Smith, Derek
name: García-Sastre, Adolfo
name: Aydillo, Teresa
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: SARS-CoV-2 Omicron subvariants are still emerging and spreading worldwide. These variants contain a high number of polymorphisms in the spike (S) glycoprotein that could potentially impact their pathogenicity and transmission. We have previously shown that the S:655Y and P681H mutations enhance S protein cleavage and syncytia formation. Interestingly, these polymorphisms are present in Omicron S protein. Here, we characterized the cleavage efficiency and fusogenicity of the S protein of different Omicron sublineages. Our results showed that Omicron BA.1 subvariant is efficiently cleaved but it is poorly fusogenic compared to previous SARS-CoV-2 strains. To understand the basis of this phenotype, we generated chimeric S protein using combinations of the S1 and S2 domains from WA1, Delta and Omicron BA.1 variants. We found that the S2 domain of Omicron BA.1 hindered efficient cell-cell fusion. Interestingly, this domain only contains six unique polymorphisms never detected before in ancestral SARS-CoV-2 variants. WA1614G S proteins containing the six individuals S2 Omicron mutations were assessed for their fusogenicity and S surface expression after transfection in cells. Results showed that the S:N856 K and N969 K substitutions decreased syncytia formation and impacted S protein cell surface levels. However, we observed that ‘first-generation’ Omicron sublineages that emerged subsequently, had convergently evolved to an enhanced fusogenic activity and S expression on the surface of infected cells while ‘second-generation’ Omicron variants have highly diverged and showed lineage-specific fusogenic properties. Importantly, our findings could have potential implications in the improvement and redesign of COVID-19 vaccines.
К ВОПРОСУ ВЛИЯНИЯ ИНГИБИНА  А  НА ПРИВЫЧНОЕ НЕВЫНАШИВАНИЕ БЕРЕМЕННОСТИ ПРИ ГИПЕРПРОЛАКТИНЕМИИ
Creators: name: Мухаммадаминова, Диёра
name: Ходжаева, Феруза
Publisher: name: Zenodo
Year: 2024

description: В нашей работе отмечены аспекты влияния ингибина  а  на привычное невынашивание беременности при гиперпролактинемии на основе литературных источников.
Additional file 1: of A randomised controlled trial assessing the severity and duration of depressive symptoms associated with a clinically significant response to sertraline versus placebo, in people presenting to primary care with depression (PANDA trial): study protocol for a randomised controlled trial
Creators: name: Salaminios, George
name: Duffy, Larisa
name: Ades, Anthony
name: Araya, Ricardo
name: Button, Katherine
name: Churchill, Rachel
name: Croudace, Tim
name: Derrick, Catherine
name: Padraig Dixon
name: Dowrick, Christopher
name: Gilbody, Simon
name: Hollingworth, William
name: Jones, Vivien
name: Kendrick, Tony
name: Kessler, David
name: Kounali, Daphne
name: Lanham, Paul
name: Malpass, Alice
name: Peters, Tim
name: Riozzie, Derek
name: Robinson, Jude
name: Sharp, Debbie
name: Thomas, Laura
name: Welton, Nicky
name: Wiles, Nicola
name: Lewis, Glyn
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Mental Health

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 122 kb)
Additional file 1: of Genetic determinants of growth hormone and GH-related phenotypes
Creators: name: Hallengren, Erik
name: Almgren, Peter
name: Svensson, Malin
name: Widet Gallo
name: EngstrĂśm, Gunnar
name: Persson, Margaretha
name: Melander, Olle
Publisher: name: Figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Hallengren_supp.docx. QC-protocol, supplementary file 1â  5. (DOCX 34Â kb)
Coreius zeni Tchang 1930
Creators: name: Ye, Enqi
name: Xing, Yingchun
name: Zhang, Chunguang
name: Zhao, Yahui
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Actinopterygii
Cypriniformes
Cyprinidae
Coreius
Coreius zeni

description: Coreius zeni Tchang, 1930 (Fig. 12)
= Coreius guichenoti (Sauvage & Dabry de Thiersant, 1874)
Holotype. 0 9716 (9633), Sichuan Province, P. R. China, no date.
description: Published as part of Ye, Enqi, Xing, Yingchun, Zhang, Chunguang & Zhao, Yahui, 2015, Catalogue of the type specimens in the fish collection of the National Zoological Museum, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, pp. 10-113 in Zootaxa 3962 (1) on page 21, DOI: 10.11646/zootaxa.3962.1.4, http://zenodo.org/record/233837