cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A pragmatic review of cost-effective evaluations of reimbursed medical devices conducted for Japan
Creators: name: LoPresti, Michael
name: Igarashi, Ataru
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Biotechnology
Cancer
Science Policy

description: The aim of this study is to examine the characteristics and quality of economic evaluations for reimbursed medical devices in Japan. A pragmatic review of cost-effectiveness evaluations (CEA) and other economic evaluations for medical devices reimbursed in Japan published between January 2010 and December 2023 was conducted using the PubMed (Medline), Japan Medical Abstracts Society (ICHUSHI Web), and the Cost-Effectiveness Analysis Registry of the Tufts Medical Center databases - as well as Google Scholar. Evaluations for devices assessed under the health technology assessment (HTA) system in Japan were also reviewed. Thirty-nine published studies were included with 20 studies (51%) for devices used to treat cardiovascular conditions, 7 studies (18%) for devices used to treat neurological/neurovascular conditions and orthopedic conditions, respectively, and 5 studies (13%) for devices used to treat other types of conditions. The number of published studies for reimbursed medical devices increased from 2017. Nearly 60% of the studies were cost-utility analyses and many were cost-consequence analyses (26%). Although the quality of the studies conducted were good, lack of data was mentioned as a key limitation of nearly all studies - with limited data in general (33%), lack of long-term outcomes data (33%), and lack data for Japan (21%) being key issues. Moreover, lack of cost data was mentioned as a limitation for nearly half (49%) of studies. As this was not a systematic literature review, some relevant studies may have been excluded. Moreover, some databases that are known to cover other journals were not used. Despite concerns about lack of sufficient outcomes data, good quality CEAs have been published for reimbursed devices in Japan. However, lack of data may still be an issue and the impact of the learning curve effect on cost-effectiveness may need to be considered more.
Clinical impact and cost-effectiveness of the updated COVID-19 mRNA autumn 2023 vaccines in Germany
Creators: name: Joshi, K
name: Scholz, S
name: Maschio, M
name: Kohli, M
name: Lee, A
name: Fust, K
name: Ultsch, B
name: vandeVelde, N
name: Beck, E
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Objectives: To assess the potential clinical impact and cost-effectiveness of coronavirus disease 2019 (COVID-19) mRNA vaccines updated for Autumn 2023 in adults aged ≥60 years and high-risk persons aged 30-59 years in Germany over a 1-year analytic time horizon (September 2023–August 2024). Methods: A compartmental Susceptible-Exposed-Infected-Recovered model was updated and adapted to the German market. Numbers of symptomatic infections, number of COVID-19 related hospitalisations and deaths, costs, and quality-adjusted life-years (QALYs) gained were calculated using a decision tree model. The incremental cost-effectiveness ratio of an Autumn 2023 Moderna updated COVID-19 (mRNA-1273.815) vaccine was compared to no additional vaccination. Potential differences between the mRNA-1273.815 and the Autumn Pfizer-BioNTech updated COVID-19 (XBB.1.5 BNT162b2) vaccines, as well as societal return on investment for the mRNA-1273.815 vaccine relative to no vaccination, were also examined. Results: Compared to no autumn vaccination, the mRNA-1273.815 campaign is predicted to prevent approximately 1,697,900 symptomatic infections, 85,400 hospitalisations, and 4,100 deaths. Compared to an XBB.1.5 BNT162b2 campaign, the mRNA-1273.815 campaign is also predicted to prevent approximately 90,100 symptomatic infections, 3,500 hospitalisations, and 160 deaths. Across both analyses we found the mRNA-1273.815 campaign to be dominant. Conclusions: The mRNA-1273.815 vaccine can be considered cost-effective relative to the XBB.1.5 BNT162b2 vaccine and highly likely to provide more benefits and save costs compared to no vaccine in Germany, and to offer high societal return on investment.
title: New transport equations for turbulent flow with variable transport properties: biomedical applications of non-Newtonian blood flow in coronary stent and stenosed carotid artery
title: Nuove equazioni di trasporto per flussi turbolenti con proprietà di trasporto variabile: applicazioni biomediche del flusso sanguigno non-Newtoniano negli stent coronarici e stenosi carotidee
titleType: AlternativeTitle
Creators: name: BOGHI, ANDREA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: turbulent flow; stent; mass diffusivity; thermal conductivity; non-Newtonian; carotid artery
subject: turbulent flow
subject: stent
subject: mass diffusivity
subject: thermal conductivity
subject: non-Newtonian
subject: carotid artery

description: 22. ciclo
description: 1 Introduction - 2 Numerical method - 3 Passive scalar equation with variable diffusivity in turbulent flow - 4 On a new passive scalar equation with variable mass diffusivity: flow between parallel plates - 5 On a new turbulent energy equation with variable thermal conductivity - 6 Two new differential equations of turbulent dissipation rate and apparent viscosity for non - 7 Influence of the non-newtonian behaviour in an image-based computational model of flow dynamics in stenosed carotid artery - 8 Three-dimensional numerical simulation of blood flow in two coronary stent
Cost-effectiveness of rimegepant oral lyophilisate compared to best supportive care for the acute treatment of migraine in the UK
Creators: name: Johnston, Karissa
name: Powell, Lauren C.
name: Popoff, Evan
name: L’Italien, Gil J.
name: Pawinski, Robert
name: Ahern, Aideen
name: Large, Sam
name: Tran, Thang
name: Jenkins, Aaron
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Pharmacology
Biological Sciences not elsewhere classified
Science Policy

description: Migraine is the most common disabling headache disorder and is characterized by recurrent throbbing head pain and symptoms of photophobia, phonophobia, nausea, and vomiting. Rimegepant 75 mg, an oral lyophilisate calcitonin gene-related peptide antagonist, is the first treatment approved for both the acute and preventative treatment of migraine, and the first acute therapy approved in over 20-years. The objective was to assess the cost-utility of rimegepant compared with best supportive care (BSC) in the UK, for the acute treatment of migraine in the adults with inadequate symptom relief after taking at least 2 triptans, or for whom triptans are contraindicated or not tolerated. A de novo model was developed to estimate incremental costs and quality-adjusted life years (QALYs), structured as a decision tree followed by Markov model. Patients received rimegepant or BSC for a migraine attack and were assessed for response (pain relief at 2-h). Responders and non-responders followed different pain trajectories over 48-h cycles. Non-responders discontinued treatment while responders continued treatment for subsequent attacks, with a proportion discontinuing over time. Data sources included a post-hoc pooled analysis of the phase 3 acute rimegepant trials (NCT03235479, NCT03237845, NCT03461757), and a long-term safety study (NCT03266588). The analysis was conducted from the perspective of the UK National Health Service and Personal Social Services over a 20-year time horizon. Rimegepant resulted in an incremental cost-utility ratio (ICUR) of £10,309 per QALY gained vs BSC, which is cost-effectiveness at a willingness to pay threshold of £30,000/QALY. Rimegepant generated +0.44 incremental QALYs and higher incremental lifetime costs (£4,492). Improved QALYs for rimegepant were a result of less time spent with severe and moderate headache pain. This study highlights the economic value of rimegepant which was found to be cost-effective for the acute treatment of migraine in adults unsuitable for triptans.
Self-Propelled Collective Motion with Multiplicative Scalar Noise
Creators: name: Haghsheno, Fatemeh
name: Mehrafarin, Mohammad
Publisher: name: arXiv
Year: 2024
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The emergence of order from initial disordered movement in self-propelled collective motion is an instance of nonequilibrium phase transition, which is known to be first order in the thermodynamic limit. Here, we introduce a multiplicative scalar noise model of collective motion as a modification of the original Vicsek model, which more closely mimics the particles' behavior. We allow for more individual movement in sparsely populated neighborhoods, the mechanism of which is not incorporated in the original Vicsek model. This is especially important in the low velocity and density regime where the probability of a clear neighborhood is relatively high. The modification, thus, removes the shortcoming of the Vicsek model in predicting continuous phase transition in this regime. The onset of collective motion in the proposed model is numerically studied in detail, indicating a first order phase transition in both high and low velocity/density regimes for systems with comparatively smaller size which is computationally desirable.
Real-world total cost of care by line of therapy in relapsed/refractory diffuse large B-Cell lymphoma
Creators: name: Gatwood, Justin
name: Masaquel, Anthony
name: Fox, David
name: Sheinson, Daniel
name: James, Cameron
name: Li, Jia
name: Hossain, Farah
name: Ross, Ryan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: Plant Biology

description: Aims: There are multiple recently approved treatments and a lack of clear standard-of-care therapies for relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). While total cost of care (TCC) by the number of lines of therapy (LoTs) has been evaluated, more recent cost estimates using real-world data are needed. This analysis assessed real-world TCC of R/R DLBCL therapies by LoT using the IQVIA PharMetrics Plus database (January 1, 2015–December 31, 2021), in US patients aged ≥18 years treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) or an R-CHOP–like regimen as first-line therapy. Methods: Treatment costs and resources in the R/R setting were assessed by LoT. A sensitivity analysis identified any potential confounding of the results caused by the impact of the COVID-19 pandemic on healthcare utilization and costs. Overall, 310 patients receiving a second- or later-line treatment were included; baseline characteristics were similar across LoTs. Inpatient costs represented the highest percentage of total costs, followed by outpatient and pharmacy costs. Results: Mean TCC per-patient-per-month generally increased by LoT ($40,604, $48,630, and $59,499 for second-, third- and fourth-line treatments, respectively). Costs were highest for fourth-line treatment for all healthcare resource utilization categories. Sensitivity analysis findings were consistent with the overall analysis, indicating results were not confounded by the COVID-19 pandemic. Limitations: There was potential misclassification of LoT; claims data were processed through an algorithm, possibly introducing errors. A low number of patients met the inclusion criteria. Patients who switched insurance plans, had insurance terminated, or whose enrollment period met the end of data availability may have had truncated follow-up, potentially resulting in underestimated costs. Conclusion: Total healthcare costs increased with each additional LoT in the R/R DLBCL setting. Further improvements of first-line treatments that reduce the need for subsequent LoTs would potentially lessen the economic burden of DLBCL.
Roma: uno studio diacronico delle trasformazioni dell'area Ostiense
Creators: name: ROGGIO, BARBARA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: Ostiense Garbatella San Paolo; topografia antica
subject: Ostiense Garbatella San Paolo
subject: topografia antica

description: 22. ciclo
Coptotettix longjiangensis Zheng & Wei 2000
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Coptotettix
Coptotettix longjiangensis

description: 58. Coptotettix longjiangensis Zheng & Wei, 2000
Specimens examined. 10 ♂ 21♀, Fangcheng (Fulong), 21°51’N, 107°52’E, 400m alt, 23 Jul. 2012, collected by Wei-An DENG.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 171, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
title: Gestione della conoscenza e capacità di assorbimento nelle imprese biotech
title: Managing knowledge and absorptive capacity in biotech firms
titleType: AlternativeTitle
Creators: name: GUZZO, ROSA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: dynamic capabilities; knowledge management; absorptive capacity; research and development; biotech industry
subject: gestione della conoscenza; capacità dinamiche; capacita' di assorbimento; ricerca e sviluppo; biotecnologie
subject: dynamic capabilities
subject: knowledge management
subject: absorptive capacity
subject: research and development
subject: biotech industry
subject: gestione della conoscenza
subject: capacità dinamiche
subject: capacita' di assorbimento
subject: ricerca e sviluppo
subject: biotecnologie

description: 22. ciclo
description: Capitolo 1: IL CONTESTO IMPRENDITORIALE DELLA RICERCA: L’INDUSTRIA BIOTECH 1.1. Aspetti introduttivi 1.2. Breve storia dell’industria delle biotecnologie 1.3. Il quadro internazionale dell’industria biotech 1.4. Le biotecnologie in Italia 1.5. I business model del red biotech. - Capitolo 2: IL DOMINIO TEORICO DI RIFERIMENTO: IL MANAGEMENT DELLA CONOSCENZA 2.1. Definizione di conoscenza 2.2. La conoscenza nelle teorie manageriali e organizzative 2.3. Le ricerche empiriche 2.4. Considerazioni di sintesi. - Capitolo 3: IL DOMINIO TEORICO DI APPROFONDIMENTO: LA CAPACITÀ DI ASSORBIMENTO COME CAPACITÀ DINAMICA 3.1. Introduzione 3.2. Le capacità dinamiche come processi di conoscenza 3.3. Il ruolo della capacità di assorbimento nel management della conoscenza 3.4. La capacità di assorbimento come capacità dinamica 3.5. La capacità di assorbimento potenziale 3.6. La capacità di assorbimento realizzata 3.7. Considerazioni di sintesi. - Capitolo 4: I MECCANISMI ORGANIZZATIVI E LA CAPACITA’ DI ASSORBIMENTO: EVIDENZE DA DUE CASI STUDIO 4.1. Introduzione 4.2. Analisi sistematica della letteratura 4.3. Quadro di riferimento teorico 4.4. Obiettivo della ricerca 4.5. Domanda di ricerca e ipotesi 4.6. Protocollo 4.7. La ricerca empirica 4.8. Risultati e verifica delle ipotesi 4.9. Discussione, conclusioni e limiti della ricerca. - BIBLIOGRAFIA
Additional file 4: of Factors behind the success story of under-five stunting in Peru: a district ecological multilevel analysis
Creators: name: Huicho, Luis
name: Huayanay-Espinoza, Carlos
name: Herrera-Perez, Eder
name: Segura, Eddy
name: Guzman, Jessica NiĂąo De
name: MarĂ­A Rivera-Ch
name: Aluisio Barros
Publisher: name: Figshare
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Ranking of departments by annual variation of coverage of RMNCH interventions [7]. (DOCX 108Â kb)
Activation of human endogenous retrovirus K and cellular modifications in human melanoma cell lines: gene expression analysis
Creators: name: AL DOSSARY, REEM
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: HERV-K; real-time PCR; gene expression; melanoma; malignant; cell transformation; microarray
subject: HERV-K
subject: real-time PCR
subject: gene expression
subject: melanoma
subject: malignant
subject: cell transformation
subject: microarray

description: 22. ciclo
description: CHAPTER 1: Introduction 1.1. Retroviruses 1.1.1. General properties of Retroviruses 1.1.2. Structure of retroviruses 1.1.3. Genomic composition of retroviruses 1.1.4. Replication of retroviruses 1.1.5. Classification of Retroviruses 1.2. HUMAN ENDOGENOUS RETROVIRUSES (HERVs) 1.2.1. General properties of HERVs 1.2.2. Classification of HERVs 1.3. HERV-K AND DISEASES 1.3.1. Pathological role of HERVs 1.3.2. Virological etiology of cancer 1.4. HERVs and human melanoma 1.4.1. HERV-K particles and human melanoma 1.4.2. HERV-K mRNA and protein expression in human melanoma 1.4.3. HERV-K and human melanoma: immunological evidences. 1.4.4. Biological events in the progression of human melanoma 1.4.5. Molecular changes in the progression of human melanoma. - CHAPTER 2. Aim of the study. - CHAPTER 3. Materials and methods 3.1. MATERIALS 3.1.1. Cell cultures 3.1.2. Microarray 3.1.3. Reverse transcription and Real-time PCR 3.2. Methods 3.2.1. Cell cultures 3.2.2. RNA extraction and quantification 3.2.3. Microarray 3.2.4. Reverse transcription and Real-time PCR. - CHAPTER 4. Results 4.1. Background 4.2. Gene expression analysis using microarray 4.3. Real time PCR. - CHAPTER 5. Discussion 5.1. Microarray-based gene expression analysis of adherent TVM-A12 1% 5.2. Microarray-based gene expression analysis of non adherent TVM-A12sp and clonesp 5.3. Confirmation of gene expression using real-time PCR. - CHAPTER 6. References
Coptotettix brachynotus Deng, Zheng & Wei 2007
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Coptotettix
Coptotettix brachynotus

description: 59. Coptotettix brachynotus Deng, Zheng & Wei, 2007
Specimens examined. 3 ♂ 5♀, Shangsi (Jiaoan), 21°53’N, 107°56’E, 400m alt, 28 Jul. 2012, collected by Wei-An DENG.
Distribution. China (Guangxi).
Nomenclatural note. The epitheton should be “ brachynotus ” not “ brachynota ” because the generic name is masculine gender.
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 171, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Fast Swarming of UAVs in GNSS-denied Feature-poor Environments without Explicit Communication
Creators: name: Horyna, Jiri
name: Kratky, Vit
name: Pritzl, Vaclav
name: Baca, Tomas
name: Ferrante, Eliseo
name: Saska, Martin
Publisher: name: arXiv
Year: 2024
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: A decentralized swarm approach for the fast cooperative flight of Unmanned Aerial Vehicles (UAVs) in feature-poor environments without any external localization and communication is introduced in this paper.
 A novel model of a UAV neighborhood is proposed to achieve robust onboard mutual perception and flocking state feedback control, which is designed to decrease the inter-agent oscillations common in standard reactive swarm models employed in fast collective motion.
 The novel swarming methodology is supplemented with an enhanced Multi-Robot State Estimation (MRSE) strategy to increase the reliability of the purely onboard localization, which may be unreliable in real environments.
 Although MRSE and the neighborhood model may rely on information exchange between agents, we introduce a communication-less version of the swarming framework based on estimating communicated states to decrease dependence on the often unreliable communication networks of large swarms.
 The proposed solution has been verified by a set of complex real-world experiments to demonstrate its overall capability in different conditions, including a UAV interception-motivated task with a group velocity reaching the physical limits of the individual hardware platforms.
description: Accepted to IEEE RA-L on March 22, 2024
Additional file 4: of Factors behind the success story of under-five stunting in Peru: a district ecological multilevel analysis
Creators: name: Huicho, Luis
name: Huayanay-Espinoza, Carlos
name: Herrera-Perez, Eder
name: Segura, Eddy
name: Guzman, Jessica NiĂąo De
name: MarĂ­A Rivera-Ch
name: Aluisio Barros
Publisher: name: Figshare
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Ranking of departments by annual variation of coverage of RMNCH interventions [7]. (DOCX 108Â kb)
Repeat cardiovascular-related procedures and real-world treatment in high-risk patients with hypercholesterolemia or mixed dyslipidemia
Creators: name: Lehrke, Michael
name: Müller, Sabrina
name: Maywald, Ulf
name: Deiters, Barthold
name: Fraass, Uwe
name: Stein, Alexandra
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: To determine the real-world treatment patterns and recurrence of cardiovascular-related procedures and hospitalizations in patients at very-high atherosclerotic risk. In this retrospective observational study, atherosclerotic cardiovascular disease (ASCVD)-related procedures and hospitalizations, and lipid-lowering therapy (LLT) medication data were assessed in adults with hypercholesterolemia or mixed dyslipidemia with an incident ASCVD-related procedure using health claims data from the German AOK PLUS (2010–2020) and GWQ ServicePlus databases (2013–2019). Differences in time-to-first event between LLT and non-LLT groups were assessed using a propensity score matched (PSM) comparison. Following the index procedure, approximately 20% of patients had at least one subsequent ASCVD-related procedure in the first 12 months, and approximately 50% had an ASCVD-related re-hospitalization. The total proportion of patients prescribed LLT prior to the index ASCVD-related procedure was approximately 30%. In the index procedure quarter, 68% of patients received a prescription for LLT (non-intensified LLT: 63%; intensified LLT: 5%); 32% did not receive any LLT. PSM comparative analysis showed a reduced risk of time to all-cause death in the LLT versus non-LLT group (AOK PLUS, hazard ratio [HR] 0.62 [95% confidence interval {CI}: 0.60–0.65]; GWQ ServicePlus, HR 0.46 [95% CI: 0.43–0.49]). Limitations inherent to retrospective health claims data including bias owing to unobservable confounders; potential incomplete capture of patients at “very-high atherosclerotic risk” given the defined nature of categorization criteria used in the study. This real-world study demonstrates that a substantial proportion of very-high-risk patients have recurrent ASCVD-related hospitalizations and events following an initial procedure. Many patients receive no LLT after an ASCVD-related procedure, and among those who do, a large percentage receive only non-intensified LLT. These findings have implications for mortality, morbidity, and healthcare costs and warrant further investigation.
How Deep Is Your Gaze? Leveraging Distance in Image-Based Gaze Analysis
Creators: name: Koch, Maurice
name: Pathmanathan, Nelusa
name: Weiskopf, Daniel
name: Kurzhals, Kuno
Publisher: name: arXiv
Year: 2024
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Image thumbnails are a valuable data source for fixation filtering, scanpath classification, and visualization of eye tracking data. They are typically extracted with a constant size, approximating the foveated area. As a consequence, the focused area of interest in the scene becomes less prominent in the thumbnail with increasing distance, affecting image-based analysis techniques. In this work, we propose depth-adaptive thumbnails, a method for varying image size according to the eye-to-object distance. Adjusting the visual angle relative to the distance leads to a zoom effect on the focused area. We evaluate our approach on recordings in augmented reality, investigating the similarity of thumbnails and scanpaths. Our quantitative findings suggest that considering the eye-to-object distance improves the quality of data analysis and visualization. We demonstrate the utility of depth-adaptive thumbnails for applications in scanpath comparison and visualization.
PUBLIC HEALTH NURSES' VIEWS ON DISASTER PREPAREDNESS: A COMPREHENSIVE STUDY.
Creators: name: Elif, Yılmaz
name: Murat, Kaya
Publisher: name: keith journal
Year: 2024
Subjects: disaster management, healthcare, preparedness, interdisciplinary collaboration, healthcare professionals.

description: Disasters, defined by the World Health Organization as sudden ecological events of extraordinary magnitude necessitating external assistance, have persistently posed severe challenges to communities throughout history. The diversity, frequency, and detrimental consequences of these calamities have touched every facet of society. Recent years have witnessed a surge in disaster occurrences, notably meteorological, climatic, and geophysical events, as indicated in the 2018 World Disaster Report. Given the heightened incidence and devastating impact of these disasters, a critical need exists for every nation to establish dynamic and accessible disaster management plans. Effective disaster management encompasses a range of activities, from pre-disaster needs assessment to post-disaster recovery efforts, including risk analysis and damage mitigation. This includes addressing the healthcare, housing, clean water, food, and safety requirements of affected individuals. Such preparedness necessitates interdisciplinary collaboration, involving healthcare professionals, security forces, fire brigades, and emergency rescue teams, to develop a dynamic, community-focused, and solution-oriented disaster management strategy. In the aftermath of disasters, the affected population faces significant challenges, such as loss of life, injuries, disabilities, and disease outbreaks. The role of healthcare professionals becomes paramount. However, empirical evidence from various national and international hospital-based studies underscores a concerning inadequacy in the preparedness of both health institutions and professionals, highlighting the pressing need for comprehensive and effective disaster preparedness measures.
title: Secondary elliptic islands in a dynamical system close to hyperbolic
title: Isole ellittiche secondarie in un sistema dinamico vicino all'iperbolicità
titleType: AlternativeTitle
Creators: name: DISCENDENTI, MARCO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: sistema dinamico; mappa simplettica; dinamica iperbolica; sistema hamiltoniano; dinamica ellittica
subject: sistema dinamico
subject: mappa simplettica
subject: dinamica iperbolica
subject: sistema hamiltoniano
subject: dinamica ellittica

description: 19. ciclo
Hedotettix gracilis Haan 1843
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Hedotettix
Hedotettix gracilis

description: 60. Hedotettix gracilis (Haan, 1843)
Specimens examined. 3 ♂ 7♀, Fangcheng (Dongzhong), 21°44’N, 107°40’E, 600m alt, 24 Aug. 2012, collected by Li-Liang LIN.
Distribution. China (Fujian, Guangxi, Yunnan, Hong Kong); India; Pakistan; Bangladesh; Sri Lanka; Burma; Thailand; Vietnam; Malaysia; Nepal; Indonesia.
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 171, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Military police investigator perspectives of a new self-reflective approach to strengthening resilience: A qualitative study
Creators: name: Crane, Monique F.
name: Rapport, Frances
name: Callen, Joanne
name: Boga, Danny
name: Gucciardi, Daniel F.
name: Sinclair, Laura
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: In this study, we explored participants’ experiences of a unique form of resilience training. The aims of this study were to obtain rich information about the participants’ experience of the resilience intervention based on adaptive self-reflection, their ability to report the private stress experience and coping efforts when faced with a stressor, their perceptions of training applicability to other contexts, and whether the training was able to encourage the reappraisal of stressors as growth opportunities. A qualitative design was employed with a sample of 21 investigator trainees from the Australian Defence Force School of Policing. Following implementation of the program, trainees provided written responses to seven open ended questions and participated in one focus group designed to embellish understanding of the survey answers. The analysis identified both strengths and limitations in the way respondents were able to recall and report on their private stress experience and coping efforts and several domains where the resilience training seemed to have its effects. Moreover, the respondents reported increased confidence in their ability to manage stressors in the future, recognition of stress in others and the potential to assist them, and a changed view of stress as an opportunity for personal development. Based on these findings, potential improvements in the training materials are recommended. Moreover, the findings suggest coping and emotion regulatory self-reflection may encourage the application of useful strategies and reinforce personal resilient capacities and coping self-efficacy.
Additional file 1: Figure S1. of GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord
Creators: name: Cave, Clinton
name: Sungjin Park
name: Marianeli Rodriguez
name: Nakamura, Mai
name: Hoke, Ahmet
name: Pletnikov, Mikhail
name: Shanthini Sockanathan
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Developmental Biology
subject: Mental Health

description: Sensory neurons exhibit neurodegenerative pathology without impaired nerve conduction in the absence of Gde2. This figure illustrates the presence of neuropathology in the primary sensory neurons of the Gde2 KO, including vacuolization, lipid accrual, and cytoskeletal accumulation; and the maintenance of peripheral sensory nerve conduction. Figure S2-related to Fig.Â 9. Conditional ablation of Gde2 in the postnatal spinal cord prevents the developmental loss of motor neurons. This figure confirms the effective conditional ablation of Gde2 following neurogenesis. In the constitutive KO, GDE2â  s absence during embryonic neurogenesis causes a reduction of alpha motor neurons in the lateral motor column; however, in the Gde2lox/-; ROSA:CreER animals, this loss is avoided by injecting 4-OHT at E17.5. Further, competitive PCR analysis shows a near complete deletion of the conditional Gde2 allele following 4-OHT delivery. Figure S3. Gde2 deletion does not perturb neuromuscular junction morphology. This figure uses wholemount immunohistochemistry to assess the integrity of the neuromuscular junction (NMJ) in aged Gde2 KO hindlimb muscle. At 19Â months, no discernible pathology is present in the Gde2 KO NMJ. (DOCX 6586 kb)
Time series bootstrap-based model order selection
Creators: name: FENGA, LIVIO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: stationary bootstrap; sieve bootstrap; SETAR models; ARMA models; information criteria; order selection
subject: stationary bootstrap
subject: sieve bootstrap
subject: SETAR models
subject: ARMA models
subject: information criteria
subject: order selection

description: 20. ciclo
description: PART I Bootstrap based ARMA order identification 1. Introduction 2. Akaike information criterion for the selection of ARMA models 3. Bootstrap for dependent data 3.1 The employed scheme: the sieve bootstrap 3.2 Definition of AIC* and the proposed B-MAICE method 4. On the asymptotic distribution of the orders selected via AIC and AIC* for ARMA processes 4.1 Two important results of Shibata and Hannan 4.2 On the asymptotic equivalence of the distribution of the orders chosen by both AIC and AIC* for ARMA models 5. The B-MAICE method and empirical results 5.1 The procedure 5.2 Some remarks on the method 5.3 Results and discussion 5.3.1 Empirical evidences 5.3.2 Conclusions. - References. - PART II Bootstrap based order determination for ARMA models: a comparison between different order selection criteria 1. Introduction 2. Order selection for time series models 2.1 The employed identification criteria 2.2 Arma model selection through minimization of selection criteria 3. The bootstrap method 3.1 The bootstrapped selection criteria 3.2 The applied bootstrap scheme 3.3 The presented B-MSCE procedure 4. Empirical Study 4.1 The experiments 4.2 Results 4.3 Final remarks - References. - PART III Bootstrap based order selection for SETAR models 1. Introduction 2. Akaike information criterion for SETAR models 3. Estimation and selection strategy for l-regimes SETAR models 4. The employed bootstrap scheme 5. Definition of beta-AIC and the proposed beta-MAICE procedure 6. Simulation study 6.1 Experimental design and simulations 7. Artificial neural network approach for the assessment of the robustness of the proposed method 7.1 Choice of the models belonging to the subset a 7.2 The employed selection criterion for artificial neural network 7.3 Empirical results - References - Conclusions
Clinical and economic impact of ventricular assist device infections: a real-world claims analysis
Creators: name: Peleg, Anton Y.
name: Feller, Erika D.
name: Müller, Marcus
name: Schulte-Eistrup, Sebastian
name: McGiffin, David
name: Zimpfer, Daniel
name: Holbrook, Reece
name: Margetta, Jamie
name: Seshadri, Swathi
name: Mokadam, Nahush A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: VAD therapy has revolutionized the treatment of end-stage heart failure, but infections remain an important complication. The objective of this study was to characterize the clinical and economic impacts of VAD-specific infections. A retrospective analysis of a United States claims database identified members ≥ 18 years with a claim for a VAD implant procedure, at least 6 months of pre-implant baseline data, and 12 months of follow-up between 1 June 2016 and 31 December 2019. Cumulative incidence of infection was calculated. Infection and non-infection cohorts were compared regarding mortality, healthcare utilization, and total cost. Regression models were used to identify risk factors associated with infections and mortality. A total of 2,259 patients with a VAD implant were included, with 369 experiencing infection (12-month cumulative incidence 16.1%). Patients with infection were 2.1 times more likely to die (p < 0.001, 95% CI [1.5–2.9]). The mean 12-month total cost per US patient was $354,339 for the non-infection cohort and $397,546 for the infection cohort, a difference of $43,207 (p < 0.0001). VAD infections were associated with higher mortality, more healthcare utilization, and higher total cost. Strategies to minimize VAD-specific infections could lead to improved clinical and economic outcomes.
Hedotettix shangsiensis Zheng & Jiang 2003
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Hedotettix
Hedotettix shangsiensis

description: 61. Hedotettix shangsiensis Zheng & Jiang, 2003
Specimens examined. 5 ♂ 2♀, Fangcheng (Dongzhong), 21°38’N, 107°38’E, 400m alt, 13 Aug. 2012, collected by Min-Ping LIN.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 171, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
La collocazione sistematica del patto di prova
Creators: name: BONO, SONIA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: patto di prova; valutazione reciproca convenienza lavoro; libera recedibilità
subject: patto di prova
subject: valutazione reciproca convenienza lavoro
subject: libera recedibilità

description: 22. ciclo
Enhancing Interactive Image Retrieval With Query Rewriting Using Large Language Models and Vision Language Models
Creators: name: Zhu, Hongyi
name: Huang, Jia-Hong
name: Rudinac, Stevan
name: Kanoulas, Evangelos
Publisher: name: arXiv
Year: 2024
Subjects: subject: Multimedia (cs.MM)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Image search stands as a pivotal task in multimedia and computer vision, finding applications across diverse domains, ranging from internet search to medical diagnostics. Conventional image search systems operate by accepting textual or visual queries, retrieving the top-relevant candidate results from the database. However, prevalent methods often rely on single-turn procedures, introducing potential inaccuracies and limited recall. These methods also face the challenges, such as vocabulary mismatch and the semantic gap, constraining their overall effectiveness. To address these issues, we propose an interactive image retrieval system capable of refining queries based on user relevance feedback in a multi-turn setting. This system incorporates a vision language model (VLM) based image captioner to enhance the quality of text-based queries, resulting in more informative queries with each iteration. Moreover, we introduce a large language model (LLM) based denoiser to refine text-based query expansions, mitigating inaccuracies in image descriptions generated by captioning models. To evaluate our system, we curate a new dataset by adapting the MSR-VTT video retrieval dataset to the image retrieval task, offering multiple relevant ground truth images for each query. Through comprehensive experiments, we validate the effectiveness of our proposed system against baseline methods, achieving state-of-the-art performance with a notable 10\% improvement in terms of recall. Our contributions encompass the development of an innovative interactive image retrieval system, the integration of an LLM-based denoiser, the curation of a meticulously designed evaluation dataset, and thorough experimental validation.
Additional file 1: of Resuscitation fluid composition affects hepatic inflammation in a murine model of early sepsis
Creators: name: Patrick, Amanda
name: Grin, Peter
name: Kraus, Nicole
name: Gold, Michelle
name: Berardocco, Matthew
name: Liaw, Patricia
name: Fox-Robichaud, Alison
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Digital supplemental content. (DOCX 3132 kb)
Additional file 9: Figure S8. of Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling
Creators: name: Berwick, Daniel
name: Javaheri, Behzad
name: Wetzel, Andrea
name: Hopkinson, Mark
name: Nixon-Abell, Jonathon
name: Grannò, Simone
name: Pitsillides, Andrew
name: Harvey, Kirsten
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Entire images of Western Blots shown in Fig. 4D and E and total β-catenin levels in aged female mouse brains A) Full blot from the image shown in Fig. 4d, plus a reprobe of the same membrane for calnexin to show that pulldowns are clean and this protein is only present in cell lysates. B) Western blotting shows no discernible differences between levels of total β-catenin in brains from aged female mice. C) Full blot from the image shown in Fig. 4e. (PDF 102 kb)
Engineering applications of ceramic foams
Creators: name: RAINER, ALBERTO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: schiume ceramiche; biomateriali; poliuretani; celle a combustibile; SOFC; ingegneria tissutale
subject: schiume ceramiche
subject: biomateriali
subject: poliuretani
subject: celle a combustibile
subject: SOFC
subject: ingegneria tissutale

description: 19. ciclo
Additional file 1: of Physician migration at its roots: a study on the emigration preferences and plans among medical students in Romania
Creators: name: ĹOimita Suciu
name: Popescu, Codruta
name: Ciumageanu, Mugur
name: Buzoianu, Anca
Publisher: name: Figshare
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Questionaire regarding migration intent. (DOCX 41Â kb)
Quantifying preferences for urea cycle disorder treatments using a discrete choice experiment
Creators: name: Edelblut, Josiah
name: Skaar, Jeffrey R.
name: Hilton, John
name: Seibt, Matthew
name: Martin, Kyle
name: Hadker, Nandini
name: Quartel, Adrian
name: Steiner, Robert D.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Urea cycle disorders (UCDs) can cause ammonia accumulation and central nervous system toxicity. Nitrogen-binding medications can be efficacious, but certain attributes may negatively impact adherence. This study sought to quantify the administration-related attributes influencing overall prescription selection and patient adherence. A web-based, quantitative survey including discrete choice experiment (DCE) methodology captured responses from health care providers for patients with UCDs. A series of hypothetical treatment profile sets with attributes such as route of administration, taste/odor, preparation instructions, packaging, dose measurement, and weight use restrictions were presented. From 16 sets of 3 hypothetical product profiles, respondents evaluated attributes most preferred for prescription selection or patient adherence. Attributes assumed a higher overall preference if relative importance (RI) scores were >16.67% (the value if all attributes were of equal importance). Preference weight scores were assessed. A nine-point Likert scale assessed respondent attitudes, such as satisfaction. A total of 51 respondents completed the survey. Respondents reported dissatisfaction with current treatments (mean [SD] = 5.4 [1.7]). For prescription selection, four attributes achieved RI >16.67%: taste/odor (24%), weight restrictions (21%), preparation instructions (18%), and route of administration (17%). For adherence, three attributes related to administration achieved RI >16.67%: taste/odor (28%), preparation instructions (21%), and route of administration (17%). Preference weights for “taste/odor masked” were higher than “not taste/odor masked” for prescription selection (mean [SD]; 1.52 [1.10] vs −1.52 [1.10]) and treatment adherence (73.8 [55.2] vs −73.8 [55.2]). This study contained a relatively small sample size. Survey respondent selection, the use of hypothetical product profiles, and exclusion of non-pharmacologic treatment options could have contributed to potential biases. Among attributes tested, taste/odor was the most important attribute influencing overall preference for both prescribing and patient adherence, with taste/odor masking preferred. Optimizing nitrogen-binding medications through masking taste/odor may support improved patient adherence and outcomes in UCDs.
Additional file 9: Figure S8. of Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling
Creators: name: Berwick, Daniel
name: Javaheri, Behzad
name: Wetzel, Andrea
name: Hopkinson, Mark
name: Nixon-Abell, Jonathon
name: Grannò, Simone
name: Pitsillides, Andrew
name: Harvey, Kirsten
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Mental Health

description: Entire images of Western Blots shown in Fig. 4D and E and total β-catenin levels in aged female mouse brains A) Full blot from the image shown in Fig. 4d, plus a reprobe of the same membrane for calnexin to show that pulldowns are clean and this protein is only present in cell lysates. B) Western blotting shows no discernible differences between levels of total β-catenin in brains from aged female mice. C) Full blot from the image shown in Fig. 4e. (PDF 102 kb)
The Impact of Light Distribution and Furniture Layout on Meeting Light Exposure Objectives in an Office – A Simulation Case Study
Creators: name: Danell, Megan
name: Hartmeyer, Steffen
name: Peterson, L.
name: Davis, R.
name: Andersen, Marilyne
name: Rockcastle, Siobhan
Publisher: name: Zenodo
Year: 2022
Subjects: Lighting, Simulation, Nursong home

description: Presentation at Building Simulation September 2021 Conference