cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Electrochemical surface processes at well defined platinum interfaces: Hydrogen underpotential deposition, and quasi-two-dimensional and three-dimensional oxide film formation.
Creators: name: Jerkiewicz, Grzegorz (Gregory).
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Chemistry, Physical.

description: The main body of research reported in this thesis was concerned with studies of H, and OH or O, chemisorption on polycrystalline and single-crystal Pt surfaces, including studies of the anodic growth of thick oxide films and distinction between the several states in which they are formed. In the work reported in the first part of this thesis, a standard procedure has been worked out for preparing polycrystalline Pt electrodes. Such electrodes reveal and sustain the same physical and electrochemical properties over long periods of time; this is probably the result of the discovery and use of the "electrochemical annealing" phenomenon. Thus, polycrystalline Pt electrodes can be well characterized in a reproducible way after selected controlled thermal and/or electrochemical pretreatments and are found to become reconverted to the same, stable and final state (the "electrochemically annealed" state) after prolonged cycling between 0.05 and 1.40 V, RHE, regardless of their initial pretreatment. At Pt anodes subjected to regimes of anodization at high controlled potentials for various periods of time, it was found that at least five states of the oxide film can be distinguished, in reduction, using the cyclic-voltammetry technique. The extent of growth of the oxide film at Pt proceeds according to a direct logarithmic law in time of growth for polarization potentials between 1.80 and 2.30 V, RHE. Upon further increase of the polarization time, the oxide growth rate increases some 400 times due to the onset of the high-field oxide growth mechanism of Mott and Cabreta. Upon increase of the polarization potential and time, it has been shown that multilayer phase oxide is generated on top of the quasi-2-d oxide. It is found that the quasi-2-d oxide can be reduced independently from the bulk-type oxide, leading to a situation where the thick-oxide film resides on bare Pt. It is also demonstrated that the quasi-2-d oxide resides between Pt and the thick oxide film. The oxide growth rate depends on the crystallographic orientation of the underlying metal surface. Cycling of "quenched" Pt(111) and Pt(100) into the oxide region results in surface restructuring (probably enhanced by the stress from quenching). Such pretreated Pt(111) and Pt(100) surfaces exhibit the same electrochemical behaviours as those of annealed Pt(111) and Pt(100). (Abstract shortened by UMI.)
title: Lesiones quísticas del páncreas: Caracterización morfológica.
Creators: name: García Camacho, Laura
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Cysts
subject: Neoplasia
subject: Cholangiography
subject: Contrast agent-intravenous
subject: CT
subject: MR
subject: Pancreas
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Los objetivos de este trabajo consisten en: -Realizar una caracterización de las distintas lesiones quísticas del páncreas,
describiendo sus aspectos morfológicos mediante las diferentes técnicas de imagen disponibles (TC y RM...
Nanomaterials for the detection and treatment of cancer
Creators: name: Smith, Rasheid
Publisher: name: University of Iowa
Year: 2020
Subjects: Cancer Detection
Cancer Immunotherapy
Cancer vaccine
Nanoparticles
Biosensors
Oncology

description: It is well known that reducing materials to the nanoscale imparts distinct physicochemical properties which can be exploited to solve many of society’s most complex problems. Solubility of drugs can be greatly increased by reducing the size of individual crystals to the nanoscale, optical absorption of light by solar cells can be increased by introducing nanostructures on its surface, uptake of immunologically active compounds can be increased by loading them into nanoparticles. These are just a few examples of the potential nanomaterials possess to solve issues plaguing different fields of research. The work presented in this dissertation demonstrates how nanomaterials can be used to improve the detection and treatment of cancer.
description: Conventional biosensors currently fall into two main categories: (1) large instruments that are expensive, slow, and accurate or (2) low cost, mass-assembled, and lower sensitivity devices. In an effort to develop a biosensor that is both accurate, fast and cost effective, a silicon nanowire based biosensor was fabricated using cost effective laboratory techniques and demonstrated that surface modifying these biosensors allowed it to bind to and detect cancer antigens. This work demonstrates that a silicon nanowire-based biosensor can be made using cost effective processes to detect cancer antigens.
description: Cancer immunotherapy has revolutionized cancer treatment options especially for late stage cancer patients with increased efficacy and reduced side effects. Treatment modalities such as checkpoint inhibitor therapy has been approved for treatment of numerous cancers and has demonstrated complete remission in some cases. However, it is only effective in a subset of patients usually because of a lack of tumor specific T cells. Cancer vaccines possess the inherent ability to circumvent this and other issues with other cancer immunotherapy modalities however cancer vaccines have fallen behind other treatment options. Locally administering adjuvants have been shown to increase the efficacy of cancer vaccines and promote in-situ immunization within the tumor. Additionally, formulating adjuvants in nanoparticles protects them from premature degradation, improves biodistribution and effectiveness, and enhances uptake. To this end, research present here demonstrates that administration of nanoparticlate adjuvant formulations at the site of the tumor increase the efficacy of an adenovirus cancer vaccine.
title: Diagnóstico por la imagen de las glándulas salivales en la infancia
Creators: name: Codina Aróztegui, Clara
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Paediatric
subject: Head and neck
subject: Ultrasound

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El objetivo de este póster es mostrar e ilustrar la patología de las glándulas salivales (parótida,
parótida accesoria,
submaxilar y sublingual) en la infancia.
Y explicar el papel de las distintas pruebas de imagen utilizadas en su...
Using Catalan words and a $q$-shuffle algebra to describe the Beck PBW basis for the positive part of $U_q(\widehat{\mathfrak{sl}}_2)$
Creators: name: Terwilliger, Paul
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Algebra (math.QA)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 17B37

description: We consider the positive part $U^+_q$ of the quantized enveloping algebra $U_q(\widehat{\mathfrak{sl}}_2)$. The algebra $U^+_q$ has a presentation involving two generators and two relations, called the $q$-Serre relations. There is a PBW basis for $U^+_q$ due to Damiani, and a PBW basis for $U^+_q$ due to Beck. In 2019 we used Catalan words and a $q$-shuffle algebra to express the Damiani PBW basis in closed form. In this paper we use a similar approach to express the Beck PBW basis in closed form. We also consider how the Damiani PBW basis and the Beck PBW basis are related to the alternating PBW basis for $U^+_q$.
description: 22 pages. arXiv admin note: text overlap with arXiv:1902.00721
Vibrations of microspheres probed with ultrashort optical pulses
Creators: name: Dehoux, T.
name: Kelf, T. A.
name: Tomoda, M.
name: Matsuda, O.
name: Wright, O. B.
name: Ueno, K.
name: Nishijima, Y.
name: Juodkazis, Saulius
name: Misawa, Hiroaki
name: Tournat, V.
name: Gusev, V. E.
Publisher: name: Swinburne
Year: 2024

description: We use ultrashort optical pulses to excite and detect vibrations of single silica spheres with a diameter of 5 μm placed at the surface of an acoustically mismatched substrate. In addition to the photoelastic detection of picosecond longitudinal acoustic pulses propagating inside the bulk, we detect gigahertz acoustic resonances of the sphere through probe beam defocusing. The mode frequencies are in close accord with those calculated from the elastic vibrations of a free sphere. We also record a resonant enhancement in the amplitude of specific modes of two touching spheres.
Case pile wave equation analysis: CAPWAPC. Evaluation of driven piles.
Creators: name: Edde, Robert D.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Engineering, Civil.

description: One of the most important aspects of a piled foundation is the bearing capacity of the individual piles. Correct quantitative evaluation of the pile capacity during pile driving requires the use of dynamic monitoring by means of the Pile Driving Analyzer. These monitoring data are combined with a wave equation analysis and processed using a special software called CAPWAP. The CAPWAP analysis is an iterative procedure whereby the calculated force trace is adjusted to agree with the one measured. The main objective of the thesis study is to produce a statistical indication of the natural variation between the results from a CAPWAP analysis performed on blows within the same soil layer. More specifically, for three selected case histories, the natural variation is studied between contiguous blows of the pile capacity, the resistance distribution between the shaft and the toe, and of the soil dynamic parameters (quakes and damping) as determined in the CAPWAP analysis. (Abstract shortened by UMI.)
Stärkung der Regelungen für (Import-)Erzeugnisse in der Chemikalienverordnung REACH
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Besonders besorgniserregende Stoffe
subject: Zulassungsverfahren
subject: REACH
subject: Europäische Chemikalienregulierung
subject: CLP Regulation
subject: Import-Produkte
subject: Handelsbeschränkung
subject: WTO
subject: CTBT
subject: Chemikalien
subject: Chemicals

description: Die EU könnte eine Zulassungspflicht für Importerzeugnisse wie Kleidung, Sportartikel und Spielzeug einführen, um Mensch und Umwelt besser vor dort enthaltenen "besonders besorgniserregenden Stoffen" zu schützen. Eine entsprechend Anpassung der europäischen ChemikalienverordnungREACHwürde nicht gegen Welthandelsrecht verstoßen, so diesesUBA-Rechtsgutachten. Eine weitere, einfache Verbesserung wäre, ein verbindliches, standardisiertes Kommunikationsformat einzuführen, in dem Hersteller für ihre Erzeugnisse neben dem Namen der enthaltenen besonders besorgniserregenden Stoffe auch deren Konzentration und die Gesamtmenge sowie Hinweise zu gefährlichen Eigenschaften und zur sicheren Verwendung und Entsorgung angeben müssen.
Quelle: www.umweltbundesamt.de

description: Die EU könnte eine Zulassungspflicht für Importerzeugnisse wie Kleidung, Sportartikel und Spielzeug einführen, um Mensch und Umwelt besser vor dort enthaltenen „besonders besorgniserregenden Stoffen“ zu schützen. Eine entsprechend Anpassung der europäischen Chemikalienverordnung ⁠REACH⁠ würde nicht gegen Welthandelsrecht verstoßen, so dieses ⁠UBA⁠-Rechtsgutachten. Eine weitere, einfache Verbesserung wäre, ein verbindliches,  standardisiertes Kommunikationsformat einzuführen, in dem  Hersteller für ihre Erzeugnisse neben dem Namen der enthaltenen besonders besorgniserregenden Stoffe auch deren Konzentration und die Gesamtmenge sowie Hinweise zu gefährlichen Eigenschaften und zur sicheren Verwendung und Entsorgung angeben müssen.
Les femmes dans le secteur informel urbain : le cas de l'Amérique centrale
Creators: name: Vachon, Tania.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Women's Studies.

description: La question initiale qui dirige et oriente notre demarche analytique pose les premisses d'une evaluation de la situation du travail informel des femmes en centramerique. En tentant de comprendre les liens qui unissent les Programmes d'ajustement structurel au travail des femmes, nous cherchons a exprimer et a mettre en evidence les dynamiques du travail feminin. En adoptant un cadre theorique feministe, soit l'approche "Genre et developpement", nous illustrons la complexite du travail des femmes et combien ce dernier, par la force de mesures economiques externes, s'est transforme au fil des ans pour s'apparenter aujourd'hui 'a un travail davantage informalise que formalise. C'est en ces termes que nous proposons une hypothese de recherche, laquelle nous amenera a examiner les diverses formes de travail informel feminin et le role du travail informel dans le processus de developpement. Par le biais d'indicateurs de nature quantitative, nous examinons l'importance de l'informalite economique des actrices et acteurs sociaux et dressons un portrait des femmes qui forment la main d'oeuvre informelle des centres urbains. (Abstract shortened by UMI.)
Conflict Handling in Time-Dependent Subjective Networks
Creators: name: Wodtko, Thomas
name: Griebel, Thomas
name: Scheible, Alexander
name: Buchholz, Michael
Publisher: name: Universität Ulm
Year: 2024
Subjects: subject: Subjective Logic
subject: DDC 620 / Engineering & allied operations
subject: Logic
subject: Logik

description: With this work, we contribute novel operators and perspectives to the field of subjective logic. We propose a novel multi-source trust revision approach enabling multi-source fusion, which considers majority tendencies to mitigate occurring conflicts. For this, the degree of conflict is extended for a multi-source use, which allows our definition of so-called conflict shares. Subsequently, combining our and existing trust revision methods, we propose a generalized trust revision approach. Extending trust revision to subjective networks describing time-dependent processes, we propose the use of sub subjective networks and further the transition to recursive subjective networks. Finally, our trust revision approach and the sub subjective network proposal are evaluated and demonstrated based on experiments, which show conflict handling favoring majorities and an efficient evaluation of time-dependent decision processes.
Supplementary document for Spectral and temporal evidence of robust photonic bound states in the continuum on terahertz metasurfaces - 3991133.pdf
Creators: name: Sanchez-Gil, Jose
name: Abujetas, Diego Romero
name: van Hoof, Niels
name: Huurne, Stan ter
name: Rivas, Jaime
Publisher: name: Optica Publishing Group
Year: 2019
Subjects: Photonics, Optoelectronics and Optical Communications

description: Numerical simulations of off-normal transmittance spectra; scattering efficiencies of isolated rods and dimers, along with polarizibilities; coupled detuned-dipole formulation.
خطوات العلاج لكل شيء وفقا لنهضة الاقتصاد الاردني 2033
Creators: name: Alelaimat, Abdul Kareem
Publisher: name: Alelaimat Chemistry Laboratory
Year: 2024

description: This is the cultural historical analysis for the treatement for all diseases deug, as J.A.F. structurized by Alasalah mechanism strategies.
Disability, prejudice and reality TV: Challenging disablism through media representations
Creators: name: Müller, Floris
name: Klijn, Marlies
name: Van Zoonen, Liesbet
Publisher: name: Swinburne
Year: 2024

description: Despite its well-established critique of the under- and misrepresentation of disability in the media, disability studies literature is not clear on how disability should best be ‘re’presented.
Critics either advocate a representational strategy with disability entirely incidental to the narrative of a media text or a ‘non-incidentalist’ strategy highlighting the exigencies of living
with disability. We argue that combining the two strategies is more in line with current media critiques and theorising. This hypothesis is tested with two experimental studies using footage from a Dutch Reality Television programme featuring participants with physical impairments. Results indicate that such positive representations of disability may initially increase affective prejudice, with more positive effects emerging only after repeated viewing. Further study into the reception of positive portrayals of disability in (entertainment) media is needed to improve our understanding of the possibilities of challenging disablism through and within the media.
Erratum: Vibrations of microspheres probed with ultrashort optical pulses (Optics Letters (2009) 34 (3740))
Creators: name: Dehoux, T.
name: Kelf, T. A.
name: Tomoda, M.
name: Matsuda, O.
name: Wright, O. B.
name: Ueno, K.
name: Nishijima, Y.
name: Juodkazis, Saulius
name: Misawa, Hiroaki
name: Tournat, V.
name: Gusev, V. E.
Publisher: name: Swinburne
Year: 2024

description: Corrects an error in Dehoux, T., Kelf, T. A., Tomoda, M., Matsuda, O., Wright, O. B., Ueno, K., Nishijima, Y., Juodkazis, S., Misawa, H., Tournat, V. and Gusev, V. E. (2009). Vibrations of microspheres probed with ultrashort optical pulses. Optics Letters, 34 (23), pp. 3740-3742. For the original article see: http://hdl.handle.net/1959.3/193672.
Fractional AC Josephson effect in a topological insulator proximitized by a self-formed superconductor
Creators: name: Rosen, Ilan T.
name: Trimble, Christie J.
name: Andersen, Molly P.
name: Mikheev, Evgeny
name: Li, Yanbin
name: Liu, Yunzhi
name: Tai, Lixuan
name: Zhang, Peng
name: Wang, Kang L.
name: Cui, Yi
name: Kastner, M. A.
name: Williams, James R.
name: Goldhaber-Gordon, David
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A lateral Josephson junction in which the surface of a 3D topological insulator serves as the weak link should support topologically protected excitations related to Majorana fermions. The resulting $4π$-periodic current-phase relationship could be detected under high-frequency excitation by the suppression of odd Shapiro steps. Here, we demonstrate such devices through the self-formation of a Pd-Te superconducting layer from a telluride topological insulator, and observe suppressed first and third Shapiro steps. Other devices, including those where the Pd-Te layer is bolstered by an additional Al layer, show no suppression of Shapiro steps, a difference supported by simulations. Though we rule out the known trivial causes of suppressed Shapiro steps in our devices, we nevertheless argue that corroborating measurements and disorder-aware theoretical descriptions of these systems are needed before confidently claiming the observation of Majorana states.
description: 10 pages, 5 figures, plus Supplemental Material
Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway
Creators: name: Ziosi, Marcello
name: Di Meo, Ivano
name: Kleiner, Giulio
name: Gao, Xing-Huang
name: Barca, Emanuele
name: Sanchez-Quintero, Maria J.
name: Tadesse, Saba
name: Schuelke, Markus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Coenzyme Q (CoQ) is an electron acceptor for sulfide‐quinone reductase (SQR), the first enzyme of the hydrogen sulfide oxidation pathway. Here, we show that lack of CoQ in human skin fibroblasts causes impairment of hydrogen sulfide oxidation, proportional to the residual levels of CoQ. Biochemical and molecular abnormalities are rescued by CoQ supplementation in vitro and recapitulated by pharmacological inhibition of CoQ biosynthesis in skin fibroblasts and ADCK3 depletion in HeLa cells. Kidneys of Pdss2kd/kd mice, which only have ~15% residual CoQ concentrations and are clinically affected, showed (i) reduced protein levels of SQR and downstream enzymes, (ii) accumulation of hydrogen sulfides, and (iii) glutathione depletion. These abnormalities were not present in brain, which maintains ~30% residual CoQ and is clinically unaffected. In Pdss2kd/kd mice, we also observed low levels of plasma and urine thiosulfate and increased blood C4‐C6 acylcarnitines. We propose that impairment of the sulfide oxidation pathway induced by decreased levels of CoQ causes accumulation of sulfides and consequent inhibition of short‐chain acyl‐CoA dehydrogenase and glutathione depletion, which contributes to increased oxidative stress and kidney failure.
title: Der stumme Frühling - Zur Notwendigkeit eines umweltverträglichen Pflanzenschutzes
title: Der stumme Frühling - Zur Notwendigkeit eines umweltverträglichen Pflanzenschutzes
titleType: AlternativeTitle
Creators: name: Schäffer, Andreas
name: Frische, Tobias
name: Filser, Juliane
Publisher: name: My University
Year: 2018

description: Chemikalien können unbeabsichtigt oder absichtlich in die Umwelt gelangen. Pflanzenschutzmittel, für die nachfolgend das Synonym Pestizide verwendet wird, stellen dabei den quantitativ bedeutendsten Anteil willentlich ausgebrachter Schadstoffe. Chemische Pestizide werden zum Schutz von Nutzpflanzen und Pflanzenprodukten vor Schadorganismen und durch sie ausgelöste Krankheiten angewendet und enthalten einzelne oder mehrere chemische, i.d.R. synthetisch hergestellte Wirkstoffe. Pestizide bekämpfen als Schadorganismen Tiere, z.B. Insekten (Insektizide) oder Nagetiere (Rodentizide), schützen vor Krankheiten wie Pilzbefall (Fungizide) oder dienen auch vereinfachten Produktionsverfahren und entsprechender Kostensenkung durch Arbeitszeitreduktion. Herbizide, die zur Bekämpfung von Unkräutern eingesetzt werden, zählen ebenfalls zu den Pestiziden. Weitere Anwendungen dienen der Wachstumsregulation von Pflanzen und der Konservierung von Pflanzenerzeugnissen. Einträge von Pestiziden sind neben dem Klimawandel, massiven Veränderungen der globalen Nährstoffkreisläufe, der Zerstörung von Lebensräumen und weiteren Faktoren eine wesentliche Größe im Konzept der planetaren (Belastungs-)Grenzen, wonach das Überschreiten kritischer Grenzwerte zu tiefgreifenden Störungen im Erdsystem führt. Quelle: Verlagsinformation
Differential Anomaly Detection for Facial Images
Creators: name: Ibsen, Mathias
name: González-Soler, Lázaro J.
name: Rathgeb, Christian
name: Drozdowski, Pawel
name: Gomez-Barrero, Marta
name: Busch, Christoph
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Cryptography and Security (cs.CR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Due to their convenience and high accuracy, face recognition systems are widely employed in governmental and personal security applications to automatically recognise individuals. Despite recent advances, face recognition systems have shown to be particularly vulnerable to identity attacks (i.e., digital manipulations and attack presentations). Identity attacks pose a big security threat as they can be used to gain unauthorised access and spread misinformation. In this context, most algorithms for detecting identity attacks generalise poorly to attack types that are unknown at training time. To tackle this problem, we introduce a differential anomaly detection framework in which deep face embeddings are first extracted from pairs of images (i.e., reference and probe) and then combined for identity attack detection. The experimental evaluation conducted over several databases shows a high generalisation capability of the proposed method for detecting unknown attacks in both the digital and physical domains.
description: Accepted at WIFS'21
3995838.pdf
Creators: name: Schwarz, Benedikt
name: Hillbrand, Johannes
name: Beiser, Maximilian
name: Andrews, Aaron
name: Strasser, Gottfried
name: Detz, Hermann
name: Schade, Anne
name: Weih, Robert
name: Höfling, Sven
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplementary material
title: Culture conditions influence conidial production by the barley pathogen Ramularia collo-cygni
title: Culture conditions influence conidial production by the barley pathogen Ramularia collo-cygni
titleType: AlternativeTitle
Creators: name: Heß, Michael
name: Sghyer, Hind
Publisher: name: My University
Year: 2019

description: The fungus Ramularia collo-cygni is the causal agent of the Ramularia leaf spot (RLS) disease of barley (Hordeum vulgare). Despite having been described over 100 years ago, our knowledge of the life cycle and epidemic development of R. collo-cygni is limited. To learn more about its epidemiology, inoculation techniques are among the major research needs since standardised inoculation procedures must be available to mimic natural infection of the pathogen under controlled conditions. The present study was conducted to obtain an insight into various factors affecting the growth and sporulation of R. collo-cygni in axenic culture. The fungus was cultured on four different media and subjected to two light regimens to determine conditions favourable for its growth and sporulation. We showed that conidial production can be enhanced by growing R. collo-cygni on barley straw agar, a medium that mimics the plant host, under white light, or on quarter-strength potato dextrose agar supplemented with V8 juice agar under ultraviolet-C light, depending on the fungal isolate. To verify the infection potential of the spores produced in axenic culture, an inoculation trial was performed. R. collo-cygni spore-inoculated barley plants accumulated fungal biomass, demonstrating successful infection. Quelle: https://link.springer.com
Optimization of Iron Oxide Tracer Synthesis for Magnetic Particle Imaging
Creators: name: Ziemian, Sabina
name: Löwa, Norbert
name: Kosch, Olaf
name: Bajj, Daniel
name: Wiekhorst, Frank
name: Schütz, Gunnar
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The optimization of iron oxide nanoparticles as tracers for magnetic particle imaging (MPI) alongside the development of data acquisition equipment and image reconstruction techniques is crucial for the required improvements in image resolution and sensitivity of MPI scanners. We present a large-scale water-based synthesis of multicore superparamagnetic iron oxide nanoparticles stabilized with dextran (MC-SPIONs). We also demonstrate the preparation of single core superparamagnetic iron oxide nanoparticles in organic media, subsequently coated with a poly(ethylene glycol) gallic acid polymer and phase transferred to water (SC-SPIONs). Our aim was to obtain long-term stable particles in aqueous media with high MPI performance. We found that the amplitude of the third harmonic measured by magnetic particle spectroscopy (MPS) at 10 mT is 2.3- and 5.8-fold higher than Resovist for the MC-SPIONs and SC-SPIONs, respectively, revealing excellent MPI potential as compared to other reported MPI tracer particle preparations. We show that the reconstructed MPI images of phantoms using optimized multicore and specifically single-core particles are superior to that of commercially available Resovist, which we utilize as a reference standard, as predicted by MPS.
The role of behavioral ecotoxicology in environmental protection
Creators: name: Ford, Alex
name: Ågerstrand, Marlene
name: Duquesne, Sabine
name: Brooks, Bryan W.
name: Gergs, René
name: Sahm, René
name: Jacob, Stefanie
name: Mohr, Silvia
name: Maack, Gerd
Publisher: name: My University
Year: 2021
Subjects: Toxikologie
Ökotoxikologie
Risikoanalyse

description: For decades, we have known that chemicals affect human and wildlife behavior. Moreover, due to recent technological and computational advances, scientists are now increasingly aware that a wide variety of contaminants and other environmental stressors adversely affect organismal behavior and subsequent ecological outcomes in terrestrial and aquatic ecosystems. There is also a groundswell of concern that regulatory ecotoxicology does not adequately consider behavior, primarily due to a lack of standardized toxicity methods. This has, in turn, led to the exclusion of many behavioral ecotoxicology studies from chemical risk assessments. To improve understanding of the challenges and opportunities for behavioral ecotoxicology within regulatory toxicology/risk assessment, a unique workshop with international representatives from the fields of behavioral ecology, ecotoxicology, regulatory (eco)toxicology, neurotoxicology, test standardization, and risk assessment resulted in the formation of consensus perspectives and recommendations, which promise to serve as a roadmap to advance interfaces among the basic and translational sciences, and regulatory practices. © 2021 The Authors
Repentance as tragic virtue : structure, genre, and theme in the Greek Life of Adam and Eve
Creators: name: Stone, Lilach
Publisher: name: University of British Columbia
Year: 2025

description: The Greek Life of Adam and Eve (GLAE), a narrative about the last days of Adam and Eve composed in the early centuries CE, has received increasing scholarly attention in recent years, including the publication of a critical edition and a commentary. There are several literary studies of the narrative, but no satisfactory account of its governing principles. This essay takes a structural approach to elucidate the GLAE’s narrative progression, genre, and theme. Narrative cohesiveness can be apprehended when the relationship between God and humans is centred. This view is possible through perceiving God in the GLAE as a humanlike agent inasmuch as God is amenable to social intercourse. The narrative is oriented around God’s wrath and the human quest for mercy, with a prayer of repentance uttered by Eve as the tipping point that introduces God’s mercy on Adam, posthumously. Eve’s prayer fits into a pattern of repentance as a form of supplication for mercy that is widespread cross-culturally, appearing in both pagan Greek and biblical precursors, as well as other early Jewish literature. Study of genre draws on theoretical work on the radial prototype-centred organization of categories to show that the GLAE tells its story in the style of Greek tragedy, in features such as telling a narrative of a legendary figure, through dialogue, with emphasis on suffering, within a scenario of endangerment. The GLAE occasionally deviates from the tragic style it establishes in order to depict God as unique: a High God in charge of fate, who never appears on the tragic stage, but who is nevertheless accessible to tragic narrative through Jewish epiphanic conventions. Repentance in the form of Eve’s prayer is a uniquely Jewish virtue that makes possible access to and reconciliation with God. In this fashion, the GLAE uses Greek conventions to promote and make comprehensible Jewish views on God, and on repentance as a virtuous way to relate to God, in a Greek cultural context.
Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination
Creators: name: Gödde, Kathrin
name: Gschwend, Olivier
name: Puchkov, Dmytro
name: Pfeffer, Carsten K.
name: Carleton, Alan
name: Jentsch, Thomas J.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Olfactory bulb
subject: Sensory processing
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::611 Menschliche Anatomie, Zytologie, Histologie

description: Synaptic inhibition in the olfactory bulb (OB), the first relay station of olfactory information, is believed to be important for odour discrimination. We interfered with GABAergic inhibition of mitral and tufted cells (M/T cells), the principal neurons of the OB, by disrupting their potassium- chloride cotransporter 2 (Kcc2). Roughly, 70% of mice died around 3 weeks, but surviving mice appeared normal. In these mice, the resulting increase in the intracellular Cl− concentration nearly abolished GABA-induced hyperpolarization of mitral cells (MCs) and unexpectedly increased the number of perisomatic synapses on MCs. In vivo analysis of odorant-induced OB electrical activity revealed increased M/T cell firing rate, altered phasing of action potentials in the breath cycle and disrupted separation of odour- induced M/T cell activity patterns. Mice also demonstrated a severely impaired ability to discriminate chemically similar odorants or odorant mixtures. Our work suggests that precisely tuned GABAergic inhibition onto M/T cells is crucial for M/T cell spike pattern separation needed to distinguish closely similar odours.
Modelling of ignition of liquid hydrocarbon droplets at high pressure.
Creators: name: Ruszalo, Renata.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, Chemical.

description: This work presents a mathematical model for the auto-ignition process of a single droplet of pure liquid hydrocarbon at high pressure. The model solves the full transient equations of continuity, species diffusion and energy in the vapour phase surrounding the droplet using finite difference techniques. The Peng-Robinson equation of state is used to describe vapour-liquid equilibrium at the droplet surface. The effects on droplet evaporation and ignition of pressure, temperature, and liquid phase diffusion of dissolved air are discussed. The model was tested with a droplet size of 1.5 mm and an ambient temperature of 973 K and pressure varying from 1 to 50 atm. For a pure (single component) fuels the ignition delay time was found to be a strong function of pressure, temperature and diameter. The ignition time decreases as pressure rises. At high pressure the reaction zone moves closer to the droplet surface. The air diffusion in the liquid phase and correction of transport properties for the effects of pressure have only small effects on ignition time. The model shows that the droplet cannot reach or pass the critical state but can only approach it asymptotically. The ignition behaviour of a two-component mixture is strongly controlled by the more volatile component. A change in pressure does not have significant effects on the behaviour of ignition time with mixture composition. Liquid diffusion has no large effect on the ignition time, but may affect the subsequent combustion processes.
title: The dynamics of resting fluctuations in the brain
title: metastability and its dynamical cortical core
titleType: Subtitle
Creators: name: Deco, Gustavo
name: Kringelbach, Morten L.
name: Jirsa, Viktor K.
name: Ritter, Petra
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Cognitive control
subject: Dynamical systems
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: In the human brain, spontaneous activity during resting state consists of rapid transitions between functional network states over time but the underlying mechanisms are not understood. We use connectome based computational brain network modeling to reveal fundamental principles of how the human brain generates large-scale activity observable by noninvasive neuroimaging. We used structural and functional neuroimaging data to construct whole- brain models. With this novel approach, we reveal that the human brain during resting state operates at maximum metastability, i.e. in a state of maximum network switching. In addition, we investigate cortical heterogeneity across areas. Optimization of the spectral characteristics of each local brain region revealed the dynamical cortical core of the human brain, which is driving the activity of the rest of the whole brain. Brain network modelling goes beyond correlational neuroimaging analysis and reveals non-trivial network mechanisms underlying non-invasive observations. Our novel findings significantly pertain to the important role of computational connectomics in understanding principles of brain function.
Perspectives on the telecommunications access methods of people with complex communication needs
Creators: name: Sellwood, Darryl
name: Wood, Denise
name: Raghavendra, Parimala
Publisher: name: Swinburne
Year: 2024

description: People with Complex Communication Needs (CCN) require improved methods of accessing telecommunications since communication barriers impact on the ability for individuals to participate fully in society. This paper reports findings from research that explores the types of telecommunications access methods adults with CCN use, the reported usefulness of these methods and the perceived usefulness of a Video-Assisted Speech-to-Speech Relay (VAS) service. The research used a mixed-methods design involving both quantitative and qualitative approaches, including an online survey and an online focus group. This paper applies Bourdieu's theory of society to post-modern perspectives on disability to examine the importance of social participation.
3995838.pdf
Creators: name: Schwarz, Benedikt
name: Hillbrand, Johannes
name: Beiser, Maximilian
name: Andrews, Aaron
name: Strasser, Gottfried
name: Detz, Hermann
name: Schade, Anne
name: Weih, Robert
name: Höfling, Sven
Publisher: name: Optica Publishing Group
Year: 2019
Subjects: Uncategorized

description: supplementary material
Stochastic power control for wireless networks: Probabilistic QoS measures
Creators: name: Lu, Shili
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Engineering, System Science.

description: For wireless network systems, iterative power control algorithms have been proposed to minimize the transmission power, while maintaining reliable communication and base stations. However, since the measurements are random, the channel characteristics always are described by Stochastic Differential Equations (SDE). Based on the stochastic approximation methods, and using time-varying step size sequences, we can get an approximation algorithm to reach an optimal power allocation. After the study of optimal power allocation, the probabilistic Quality of Service (QoS) measures are introduced to evaluate the performance of any control strategy. It provides tight bounds that relate to the probability of failure in achieving the desired QoS requirements. This thesis addresses mobile systems consisting of M transmitters and M receivers, which are subject to motion, and their power is described by SDE. The optimal power control problem is formulated, and the outage probability corresponding to a desired QoS requirements is computed using Moment Generating Function (MGF). Numerical results show that each user needs only to know its own channel gain and its own output assigned by the base station to update the transmitter power in order to maintain a desired Signal to Interference Ratio (SIR) and QoS requirement at the receiver.
No Free Lunch: Balancing Learning and Exploitation at the Network Edge
Creators: name: Mason, Federico
name: Chiariotti, Federico
name: Zanella, Andrea
Publisher: name: arXiv
Year: 2021
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Over the last few years, the DRL paradigm has been widely adopted for 5G and beyond network optimization because of its extreme adaptability to many different scenarios. However, collecting and processing learning data entail a significant cost in terms of communication and computational resources, which is often disregarded in the networking literature. In this work, we analyze the cost of learning in a resource-constrained system, defining an optimization problem in which training a DRL agent makes it possible to improve the resource allocation strategy but also reduces the number of available resources. Our simulation results show that the cost of learning can be critical when evaluating DRL schemes on the network edge and that assuming a cost-free learning model can lead to significantly overestimating performance.
description: 6 pages, 4 figures, 2 tables. This paper has been submitted to IEEE ICC 2022. Copyright IEEE 2021
Outlier-Based Identification of Copy Number Variations Using Targeted Resequencing in a Small Cohort of Patients with Tetralogy of Fallot
Creators: name: Bansal, Vikas
name: Dorn, Cornelia
name: Grunert, Marcel
name: Klaassen, Sabine
name: Hetzer, Roland
name: Berger, Felix
name: Sperling, Silke R.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2013
Subjects: subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie

description: Copy number variations (CNVs) are one of the main sources of variability in the human genome. Many CNVs are associated with various diseases including cardiovascular disease. In addition to hybridization-based methods, next- generation sequencing (NGS) technologies are increasingly used for CNV discovery. However, respective computational methods applicable to NGS data are still limited. We developed a novel CNV calling method based on outlier detection applicable to small cohorts, which is of particular interest for the discovery of individual CNVs within families, de novo CNVs in trios and/or small cohorts of specific phenotypes like rare diseases. Approximately 7,000 rare diseases are currently known, which collectively affect ~6% of the population. For our method, we applied the Dixon’s Q test to detect outliers and used a Hidden Markov Model for their assessment. The method can be used for data obtained by exome and targeted resequencing. We evaluated our outlier- based method in comparison to the CNV calling tool CoNIFER using eight HapMap exome samples and subsequently applied both methods to targeted resequencing data of patients with Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease. In both the HapMap samples and the TOF cases, our method is superior to CoNIFER, such that it identifies more true positive CNVs. Called CNVs in TOF cases were validated by qPCR and HapMap CNVs were confirmed with available array-CGH data. In the TOF patients, we found four copy number gains affecting three genes, of which two are important regulators of heart development (NOTCH1, ISL1) and one is located in a region associated with cardiac malformations (PRODH at 22q11). In summary, we present a novel CNV calling method based on outlier detection, which will be of particular interest for the analysis of de novo or individual CNVs in trios or cohorts up to 30 individuals, respectively.
Transcriptional analysis of cell division genes in Neisseria gonorrhoeae.
Creators: name: Francis, Finola
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Biology, Molecular.

description: This work represents the first study of the regulation of cell division genes in the Gram negative coccus Neisseria gonorrhoeae, and this regulation was studied under aerobic and anaerobic growth conditions using two different gonococcal strains: CH811 and FA1090. Three different clusters of cell division genes were investigated: the mur-fts cluster, the ftsEX cluster, and the min cluster corresponding to homologues at the 2 min, the 78 min, and the 26 min region of the Escherichia coli chromosome, respectively. Driven by initial DNA sequencing of the pivotal cell division gene ftsZ in our laboratory, further genomic analysis using the raw data from the N. gonorrhoeae FA1090 Genome Project was used to identify the genetic organization of the mur-fts cluster as well as the min cluster. (Abstract shortened by UMI.)
Ethical Implications of the Mild Encephalitis Hypothesis of Schizophrenia
Creators: name: Riedmueller, Rita
name: Mueller, Sabine
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: schizophrenia
subject: ethics
subject: medical
subject: mild encephalitis
subject: stigmatization
subject: compulsory treatment
subject: autoimmune encephalitis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Schizophrenia is a serious mental disease with a high mortality rate and severe social consequences. Due to insufficient knowledge about its etiopathogenesis, curative treatments are not available. One of the most promising new research concepts is the mild encephalitis hypothesis of schizophrenia, developed mainly by Karl Bechter and Norbert Müller. According to this hypothesis, a significant subgroup of schizophrenia patients suffer from a mild, but chronic, form of encephalitis with markedly different etiologies ranging from viral infections, traumas to autoimmune diseases. This inflammatory process is thought to occur in the beginning or during the course of the disease. In this article, we investigate the consequences of the mild encephalitis hypothesis of schizophrenia for the scientific community, and evaluate these consequences ethically. The mild encephalitis hypothesis implies that schizophrenia would no longer be considered an incurable psychiatric disorder. Instead, it would be considered a chronic, but treatable, neurological disease. This paradigm shift would doubtlessly have significant consequences: (1) major reforms would be necessary in the theoretical conceptualization of schizophrenia, which would challenge the psychiatric diagnostic systems, Diagnostic and Statistical Manual of Mental Disorders version 5 and ICD-10. (2) Psychotic patients should be treated in interdisciplinary teams, optimally in neuropsychiatric units; additionally, specialists for endocrinology, diabetology, and cardiology should be consulted for the frequently occuring somatic comorbidities. (3) Current diagnostic procedures and (4) therapies would have to be modified significantly. (5) There might be repercussions for the pharmaceutical industry as well: first, because old drugs with expired patent protection could partly replace expensive drugs and, second, because there would be a demand for the development of new anti-inflammatory drugs. (6) Legal evaluation of compulsory treatment orders might have to be reconsidered in light of causal therapies; leading to increased legal approval and reduced need for compulsory treatment orders due to better patient compliance. (7) The social inclusion of patients might improve, if treatment became more effective regarding cognitive and social functioning. (8) The stigmatization of patients and their relatives might decrease.
Vaginal health and hygiene practices and product use in Canada: a national cross-sectional survey
Creators: name: Crann, Sara E.
name: Cunningham, Shannon
name: Albert, Arianne
name: Money, Deborah M.
name: O’Doherty, Kieran C.
Publisher: name: BioMed Central
Year: 2018

description: Background: The vaginal microbiome influences quality of life and health. The composition of vaginal microbiota can be affected by various health behaviors, such as vaginal douching. The purpose of this study was to examine the types and prevalence of diverse vaginal/genital health and hygiene behaviors among participants living in Canada and to examine associations between behavioral practices and adverse gynecological health conditions. Method: An anonymous online survey, available in English and French, was distributed across Canada. The sample consisted of 1435 respondents, 18 years or older, living in Canada. Results: Respondents reported engaging in diverse vaginal/genital health and hygiene behavioral practices, including the use of commercially manufactured products and homemade and naturopathic products and practices. Over 95% of respondents reported using at least one product in or around the vaginal area. Common products and practices included vaginal/genital moisturizers, anti-itch creams, feminine wipes, washes, suppositories, sprays, powders, and waxing and shaving pubic hair. The majority of the sample (80%) reported experiencing one or more adverse vaginal/genital symptom in their lifetime. Participants who had used any vaginal/genital product(s) had approximately three times higher odds of reporting an adverse health condition. Several notable associations between specific vaginal/genital health and hygiene products and adverse health conditions were identified. Conclusions: This study is the first of its kind to identify the range and prevalence of vaginal/genital health and hygiene behaviors in Canada. Despite a lack of credible information about the impact of these behaviors on women’s health, the use of commercially manufactured and homemade products for vaginal/genital health and hygiene is common. Future research can extend the current exploratory study by identifying causal relationships between vaginal/genital health and hygiene behaviors and changes to the vaginal microbiome.