cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2: of Training the next generation of physician researchers â Vanderbilt Medical Scholars Program
Creators: name: Brown, Abigail
name: Chipps, Teresa
name: Tebeb Gebretsadik
name: Ware, Lorraine
name: Islam, Jessica
name: Finck, Luke
name: Barnett, Joey
name: Hartert, Tina
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Survey. (PDF 770 kb)
Continuous data assimilation for the magnetohydrodynamic equations in 2D using one component of the velocity and magnetic fields
Creators: name: Biswas, Animikh
name: Hudson, Joshua
name: Larios, Adam
name: Pei, Yuan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: Dynamical Systems (math.DS)
subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 76D55, 76W05, 93C20, 35Q35

description: We propose several continuous data assimilation (downscaling) algorithms based on feedback control for the 2D magnetohydrodynamic (MHD) equations. We show that for sufficiently large choices of the control parameter and resolution and assuming that the observed data is error-free, the solution of the controlled system converges exponentially (in $L^2$ and $H^1$ norms) to the reference solution independently of the initial data chosen for the controlled system. Furthermore, we show that a similar result holds when controls are placed only on the horizontal (or vertical) variables, or on a single Elsässer variable, under more restrictive conditions on the control parameter and resolution. Finally, using the data assimilation system, we show the existence of abridged determining modes, nodes and volume elements.
description: 34 pages, submitted to SIAM Journal on Mathematical Analysis
The influence of bulkiness of the amino acid residue on the liquid crystalline behaviours of some fluorinated compounds
Creators: name: Chu, Jinming
name: Wu, Limin
name: Guo, Yongmin
name: Li, Yi
name: Li, Baozong
name: Yang, Yonggang
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: A series of fluorinated compounds with an amino acid residue are synthesized, which show smectic phases. The bulkiness of the side group of the amino acid residue plays an important role in the temperature ranges of the mesophases and clearing points. The compound with a glycine residue exhibits the widest mesomorphic temperature range. However, the compound with a cyclohexylglycine residue exhibits only a monotropicSmA phase. The phenyl groups of the amino acid residues also strongly affect the formation of mesophase. With decreasing the distance between the chiral center and the phenyl group, the temperature range of the mesophase decreases.
Predictive performance of different bleeding risk scores in patients with atrial fibrillation and acute coronary syndrome or undergoing percutaneous coronary intervention
Creators: name: Lyu, Si-Qi
name: Zhu, Jun
name: Wang, Juan
name: Wu, Shuang
name: Zhang, Han
name: Shao, Xing-Hui
name: Yang, Yan-Min
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Mental Health
subject: Hematology

description: This study aims to evaluate the predictive values of the HAS-BLED, ORBIT, ATRIA, REACH, PARIS, and PRECISE-DAPT scores in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) who received both anticoagulant and antiplatelet therapy. 930 patients were consecutively recruited and followed up for 1 year. The primary endpoints were BARC class ≥3 bleeding and BARC class ≥2 bleeding. BARC class ≥3 bleeding occurred in 36 patients(3.9%), while BARC class ≥2 bleeding was seen in 134 patients (14.4%). The predictive performance of the HAS-BLED score for BARC class ≥3 bleeding was unsatisfactory (c-statistic = 0.575). The discrimination of the ATRIA, ORBIT, PARIS, and PRECISE-DAPT scores was also low-to-moderate. The REACH score was useless in bleeding risk stratification for this population. Multivariable logistic regression indicated that previous bleeding events and hemoglobin were two independent predictors of BARC class ≥3 bleeding. Compared to the HAS-BLED score, the model constructed by previous bleeding events and hemoglobin displayed a significant improvement in bleeding risk prediction [c-statistics: 0.704 vs. 0.575 (p = .008), NRI = 0.662,IDI = 0.049]. In patients with AF and ACS or undergoing PCI who received anticoagulant+antiplatelet therapy, the HAS-BLED, ORBIT, ATRIA, REACH, PARIS, and PRECISE-DAPT scores displayed only low-to-moderate performance in predicting BARC class≥3 bleeding. Future studies are required to develop more reliable scoring systems for bleeding risk evaluation in this population.
Two-dimensional energy spectra in high Reynolds number turbulent boundary layers
Creators: name: Chandran, Dileep
name: Baidya, Rio
name: Monty, Jason P.
name: Marusic, Ivan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Here we report the measurements of two-dimensional (2-D) spectra of the streamwise velocity ($u$) in a high Reynolds number turbulent boundary layer. A novel experiment employing multiple hot-wire probes was carried out at friction Reynolds numbers ranging from 2400 to 26000. Taylor's frozen turbulence hypothesis is used to convert temporal-spanwise information into a 2-D spatial spectrum which shows the contribution of streamwise ($λ_x$) and spanwise ($λ_y$) length scales to the streamwise variance at a given wall height ($z$). At low Reynolds numbers, the shape of the 2-D spectra at a constant energy level shows $λ_y/z \sim (λ_x/z)^{1/2}$ behaviour at larger scales, which is in agreement with the existing literature at a matched Reynolds number obtained from direct numerical simulations. However, at high Reynolds numbers, it is observed that the square-root relationship tends towards a linear relationship ($λ_y \sim λ_x$) as required for self-similarity and predicted by the attached eddy hypothesis.
description: 11 pages, 6 figures
Additional file 2: of Leucine and ACE inhibitors as therapies for sarcopenia (LACE trial): study protocol for a randomised controlled trial
Creators: name: Band, Margaret
name: Sumukadas, Deepa
name: Struthers, Allan
name: Avenell, Alison
name: Donnan, Peter
name: Kemp, Paul
name: Smith, Karen
name: Hume, Cheryl
name: Hapca, Adrian
name: Witham, Miles
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Participant information leaflet for the LACE trial. (PDF 467Â kb)
Leveraging High Resolution Spectra to Understand Black Hole Spectra
Creators: name: Nowak, Michael A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: For the past 17 years, both XMM-Newton and Chandra have brought the powerful combination of high spatial and spectral resolution to the study of black hole systems. Each of these attributes requires special consideration--- in comparison to lower spatial resolution, CCD quality spectra--- when modeling observations obtained by these spacecraft. A good understanding of the high resolution spectra is in fact required to model properly lower resolution CCD spectra, with the Reflection Grating Spectrometer (RGS) instrument on XMM-Newton maintaining the highest "figure of merit" at soft X-ray energies for all missions flying or currently planned for the next decade. Thanks to its even higher spectral resolution, the use of Chandra-High Energy Transmission Gratings (HETG), albeit with longer integration times, allows for one to bring further clarity to RGS studies. A further promising route for continued studies is the combination of high spectral resolution at soft X-rays, via RGS and/or HETG, with contemporaneous broadband coverage extending to hard X-rays (e.g., NuSTAR or INTEGRAL spectra). Such studies offer special promise for answering fundamental questions about accretion in black hole systems; however, they have received only moderate consideration to date. This may be due in part to the difficulty of analyzing high resolution spectra. In response, we must continue to develop software tools that make the analysis of high resolution X-ray spectra more accessible to the wider astrophysics community.
description: 7 pages, 5 figures, to appear in Astronomische Nachrichten, presented at the XMM-Newton: The Next Decade conference, ESAC, Madrid, Spain, 9 - 11 May 2016
title: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains, f.221
Creators: name: Rouzeau, Benoît
name: Rouzeau, Benoît
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: subject: cistercien
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains. Numérisation en mode image
description: Relation: https://cisterciensetressources.lamop.fr/
description: Bibliographic citation: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains, f.221, in Projet Cisterciens et Ressources [Ressource en ligne], https://cisterciensetressources.lamop.fr
description: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains, f. 221
Mapping densely packed αIIbβ3 receptors in murine blood platelets with expansion microscopy
Creators: name: Heil, Hannah S.
name: Aigner, Max
name: Maier, Sophia
name: Gupta, Prateek
name: Evers, Luise M.C.
name: Göb, Vanessa
name: Kusch, Charly
name: Meub, Mara
name: Nieswandt, Bernhard
name: Stegner, David
name: Heinze, Katrin G.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Interrogating platelets and their densely packed, highly abundant receptor landscape is key to understand platelet clotting, a process that can save lives when stopping blood loss after an injury, but also kill when causing heart attack, stroke, or pulmonary embolism. The underlying key receptor distributions and interactions, in particular the relevance of integrin clustering, are not fully understood is because of highly abundant and densely distributed αIIbβ3 receptors. This makes receptor distributions difficult to assess even by super-resolution fluorescence microscopy. Here, we combine dual-color expansion and confocal microscopy with colocalization analysis to assess platelet receptor organization without the need of a super-resolution microscope. We show that 4x expansion is highly straight-forward for super-resolution microscopy of platelets, while 10x expansion provides higher precision at the price of increased efforts in sample preparation and imaging. Quantifying various receptor colocalization scenarios we demonstrate that expansion microscopy can pinpoint receptor distributions and interactions in resting and activated platelets being superior to conventional methods that fail in such dense 3D scenarios with highly abundant receptors. We reveal the presence of αIIbβ3 clusters in resting platelets, as well as in activated platelets, indicating that they contribute to the rapid platelet response during platelet clotting.
Living with ghosts: American narratives constructing North Korea : Masters of Research in the Modern History, Politics and International Relations, Macquarie University, NSW, Australia
Creators: name: Vogt, Richard
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: While the Korean peninsula looms as a regional security threat for most of North East Asia, North Korea is deliberately constructed as a global threat by the US. This thesis fills an important gap in the existing literature by exploring alternative questions raised by critical writers on what is often referred to as the "problem" of North Korea, especially in relation to memory. To organise these questions, Baudrillard's order of simulacrum is employed to help explore the concept of memory curation and how it relates to a renewed aesthetic turn in international relations studies. Baudrillard's simulacra is effective when also coupled with Derrida's notion of post-Cold War hauntology. In current US foreign policy North Korea is marginalised, too often an afterthought of US international concern. Traditional security studies have failed to fully account for this marginalisation. Yet for Pyongyang the Korean War has never been forgotten, while Washington struggles to remember it. Acknowledging this, the core questions this thesis seeks to answer are: what have been the main narratives employed by the US, preventing North Korea's normalisation in the international system? And, has this American behaviour helped in reinforcing regime stability in Pyongyang, allowing North Korea to fortify itself against American aggression?
REPORT—Reporting and evaluation of prediction models in organ transplantation: a scoping review protocol
Creators: name: Held, Ulrike
name: Deforth, Manja
name: Magini, Giulia
name: Camenisch, Sabine
name: Schwab, Simon
name: Müller, Thomas
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Medicine and Health Sciences
subject: organ donation
subject: prediction models
subject: transplantation

description: Background: Clinical prediction models for prognosis can be used to predict outcomes and support decision-making. Previous research criticized the quality of prediction models concerning poor reporting and the risk of bias. How this applies to prediction models in organ donation and transplantation needs to be clarified. Therefore, this scoping review aims to assess prediction models used in transplant centers in Switzerland and update clinicians on the transparency, quality of reporting, and risk of bias of these tools.
Methods: We will use expert interviews and a survey with transplant clinicians to collect prediction models used in clinical practice in the context of organ donation and transplantation at Swiss transplant centers. We will apply the reporting guideline for transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD) and the prediction model risk of bias assessment tool (PROBAST). The scoping review will report on whether prediction models were transparently reported, the risk of bias, and concerns regarding its applicability.
Discussion: Assessing clinical prediction models can give clinicians important context when using risk calculators in clinical decision-making. Moreover, by assessing the limitations of existing prediction models, this study can inform further research to develop novel or update existing models to improve the decision-making at transplant centers. We expect to find clinical prediction models based on machine learning models, and their evaluation regarding reporting quality and risk of bias assessment will pose specific challenges.
Multi-Site Harmonization of Diffusion MRI Data via Method of Moments
Creators: name: Shen, Dinggang
name: Chen, Geng
name: Wu, Ye
name: Huynh, Khoi Minh
name: Yap, Pew-Thian
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2019

description: Diffusion MRI is a powerful tool for non-invasive probing of brain tissue microstructure. Recent multi-center efforts in the acquisition and analysis of diffusion MRI data significantly increase sample sizes and hence improve sensitivity and reliability in detecting subtle changes associated with development, aging, and diseases. However, discrepancies resulting from different scanner vendors, acquisition protocols, and image reconstruction algorithms can cause data incompatibility across imaging centers. In this paper, we introduce a model-free method that is based on the method of moments for the direct harmonization of diffusion MRI data to reduce site-specific variations. Our method directly harmonizes diffusion-attenuated signal without the need to fit any diffusion model. Moreover, our method allows the explicit definition of well-behaved mapping functions with properties such as invertibility, smoothness, and injectivity. We show that our method is effective in lowering the variations of diffusion scalars of traveling human phantoms scanned at different sites from 1%-3% to less than 0.9% for fractional anisotropy (FA) and mean diffusivity and from 1%-2.5% to 0.3%-1.2% for generalized FA. We also demonstrate its ability in preserving individual differences and in increasing across-site consistency in tractography and white matter connectivity.
Additional file 6 of Comprehensive genomic characterization of NAC transcription factor family and their response to salt and drought stress in peanut
Creators: name: Yuan, Cuiling
name: Li, Chunjuan
name: Lu, Xiaodong
name: Zhao, Xiaobo
name: Yan, Caixia
name: Wang, Juan
name: Sun, Quanxi
name: Shan, Shihua
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 6. Arabidopsis NAC proteins.
Locking free and gradient robust H(div)-conforming HDG methods for linear elasticity
Creators: name: Fu, Guosheng
name: Lehrenfeld, Christoph
name: Linke, Alexander
name: Streckenbach, Timo
Publisher: name: Weierstrass Institute
Year: 2020
Subjects: subject: linear elasticity
subject: nearly incompressible
subject: locking phenomenon
subject: volume-locking
subject: gradient-robustness
subject: discontinuous Galerkin
subject: H(div)-conforming HDG methods
subject: 65N30
subject: 65N12
subject: 74B05
subject: 76D07

description: Robust discretization methods for (nearly-incompressible) linear elasticity are free of volume-locking and gradient-robust. While volume-locking is a well-known problem that can be dealt with in many different discretization approaches, the concept of gradient-robustness for linear elasticity is new. We discuss both aspects and propose novel Hybrid Discontinuous Galerkin (HDG) methods for linear elasticity. The starting point for these methods is a divergence-conforming discretization. As a consequence of its well-behaved Stokes limit the method is gradient-robust and free of volume-locking. To improve computational efficiency, we additionally consider discretizations with relaxed divergence-conformity and a modification which re-enables gradient-robustness, yielding a robust and quasi-optimal discretization also in the sense of HDG superconvergence.
Conjunction in translation from English to Arabic: a corpus-based study
Creators: name: Alasmri, Ibrahim Fayz
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Against the background of existing corpus-based research on the recurrent features of translated language, this study set out to investigate two main research questions: (1) What are the differences between translated and non-translated Arabic regarding the use of conjunctive markers? (2) What are the differences in register-related preferences for conjunctive markers between translated and non-translated Arabic? This study was conducted utilising a comparable corpus of translated and non-translated Arabic across two registers, namely creative fiction and legal texts. Conjunctive markers, as a cohesive pattern, were used as an operationalisation to investigate five features of translated language in this language pair: explicitation, simplification, normalisation, levelling out, and interference. A quantitative and qualitative analysis was carried out to investigate whether the independent variables of corpus and register have any significant main effects on the frequency of a set of conjunctive markers, as well as whether there is a significant interaction in the effects of these independent variables on the frequency of conjunctive markers. The findings from the investigation confirm that there are some differences between conjunction use in translated and non-translated Arabic, providing some support for features such as interference, normalisation and explicitation. Register has a strong and consistent effect on conjunction use, and the study also demonstrates that there are interaction effects between translation status and register that are specific to particular conjunctions, such that explicitation effects are only evident in some registers and not others, and only for particular conjunctions.
Root separation for reducible monic polynomials of odd degree
Creators: name: Dujella, Andrej
name: Pejkovic, Tomislav
Publisher: name: arXiv
Year: 2017
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11C08, 12D10, 11B37

description: We study root separation of reducible monic integer polynomials of odd degree. Let h(P) be the naive height, sep(P) the minimal distance between two distinct roots of an integer polynomial P(x) and sep(P)=h(P)^{-e(P)}. Let e_r*(d)=limsup_{deg(P)=d, h(P)-> +infty} e(P), where the limsup is taken over the reducible monic integer polynomials P(x) of degree d. We prove that e_r*(d) <= d-2. We also obtain a lower bound for e_r*(d) for d odd, which improves previously known lower bounds for e_r*(d) when d = 5, 7, 9.
description: 8 pages, to appear in Rad Hrvat. Akad. Znan. Umjet. Mat. Znan
MPEC 2024-N108 : 2024 NM2
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 NM2

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Network-Targeted, Multi-site Direct Cortical Stimulation Enhances Working Memory by Modulating Phase Lag of Low-Frequency Oscillations
Creators: name: Riddle, Justin
name: Shin, Hae Won
name: Huang, Wei Angel
name: Froehlich, Flavio
name: Hadar, Eldad
name: Alagapan, Sankaraleengam
Publisher: name: Elsevier
Year: 2019

description: Working memory is mediated by the coordinated activation of frontal and parietal cortices occurring in the theta and alpha frequency ranges. Here, we test whether electrically stimulating frontal and parietal regions at the frequency of interaction is effective in modulating working memory. We identify working memory nodes that are functionally connected in theta and alpha frequency bands and intracranially stimulate both nodes simultaneously in participants performing working memory tasks. We find that in-phase stimulation results in improvements in performance compared to sham stimulation. In addition, in-phase stimulation results in decreased phase lag between regions within working memory network, while anti-phase stimulation results in increased phase lag, suggesting that shorter phase lag in oscillatory connectivity may lead to better performance. The results support the idea that phase lag may play a key role in information transmission across brain regions. Thus, brain stimulation strategies to improve cognition may require targeting multiple nodes of brain networks.
Deformation Theory for Finite Cluster Complexes
Creators: name: Ilten, Nathan
name: Chávez, Alfredo Nájera
name: Treffinger, Hipolito
Publisher: name: arXiv
Year: 2021
Subjects: subject: Algebraic Geometry (math.AG)
subject: Commutative Algebra (math.AC)
subject: Combinatorics (math.CO)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: We study the deformation theory of the Stanley-Reisner rings associated to cluster complexes for skew-symmetrizable cluster algebras of geometric and finite cluster type. In particular, we show that in the skew-symmetric case, these cluster complexes are unobstructed, generalizing a result of Ilten and Christophersen in the $A_n$ case.
 We also study the connection between cluster algebras with universal coefficients and cluster complexes. We show that for a full rank positively graded cluster algebra $\mathcal{A}$ of geometric and finite cluster type, the cluster algebra $\mathcal{A}^{\mathrm{univ}}$ with universal coefficients may be recovered as the universal family over a partial closure of a torus orbit in a multigraded Hilbert scheme. Likewise, we show that under suitable hypotheses, the cluster algebra $\mathcal{A}^{\mathrm{univ}}$ may be recovered as the coordinate ring for a certain torus-invariant semiuniversal deformation of the Stanley-Reisner ring of the cluster complex.
 We apply these results to show that for any cluster algebra $\mathcal{A}$ of geometric and finite cluster type, $\mathcal{A}$ is Gorenstein, and $\mathcal{A}$ is unobstructed if it is skew-symmetric. Moreover, if $\mathcal{A}$ has enough frozen variables then it has no non-trivial torus-invariant deformations. We also study the Gröbner theory of the ideal of relations among cluster and frozen variables of $\mathcal{A}$. As a byproduct we generalize previous results in this setting obtained by Bossinger, Mohammadi and Nájera Chávez for Grassmannians of planes and $\text{Gr}(3,6)$.
description: 57 pages. v2: minor changes. Resolved one conjecture from v1
Multiscale neural modeling of resting-state fMRI reveals executive-limbic malfunction as a core mechanism in major depressive disorder
Creators: name: Zhang, Han
name: Chen, Yaoping
name: Li, Danian
name: Shen, Dinggang
name: Zheng, Yanting
name: Wu, Ye
name: Qiu, Shijun
name: Liu, Yujie
name: Liang, Xinyu
name: Cui, Ying
name: Yap, Pew-Thian
name: Li, Guoshi
Publisher: name: Elsevier
Year: 2021

description: Major depressive disorder (MDD) represents a grand challenge to human health and society, but the underlying pathophysiological mechanisms remain elusive. Previous neuroimaging studies have suggested that MDD is associated with abnormal interactions and dynamics in two major neural systems including the default mode - salience (DMN-SAL) network and the executive - limbic (EXE-LIM) network, but it is not clear which network plays a central role and which network plays a subordinate role in MDD pathophysiology. To address this question, we refined a newly developed Multiscale Neural Model Inversion (MNMI) framework and applied it to test whether MDD is more affected by impaired circuit interactions in the DMN-SAL network or the EXE-LIM network. The model estimates the directed connection strengths between different neural populations both within and between brain regions based on resting-state fMRI data collected from normal healthy subjects and patients with MDD. Results show that MDD is primarily characterized by abnormal circuit interactions in the EXE-LIM network rather than the DMN-SAL network. Specifically, we observe reduced frontoparietal effective connectivity that potentially contributes to hypoactivity in the dorsolateral prefrontal cortex (dlPFC), and decreased intrinsic inhibition combined with increased excitation from the superior parietal cortex (SPC) that potentially lead to amygdala hyperactivity, together resulting in activation imbalance in the PFC-amygdala circuit that pervades in MDD. Moreover, the model reveals reduced PFC-to-hippocampus excitation but decreased SPC-to-thalamus inhibition in MDD population that potentially lead to hypoactivity in the hippocampus and hyperactivity in the thalamus, consistent with previous experimental data. Overall, our findings provide strong support for the long-standing limbic-cortical dysregulation model in major depression but also offer novel insights into the multiscale pathophysiology of this debilitating disease.
Through the eyes of young children: experiences of children and families in a rebuilding conflict-affected context : a case study from Sri Lanka
Creators: name: Hettitantri, Nanditha Janajeevi
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: In response to a worldwide increase in armed conflict and the subsequent displacement of millions of families, governments and non-government organisations are expending huge amount of resources on supports and services for populations in conflict-affected contexts. While there is a rich literature about conflict-affected populations, there appear to be a limited number of studies which focus on the lived realities of young children in areas emerging from armed conflict and violence. Research that includes young children’s perspectives is particularly rare. This study argues that the voices of young children and families who are directly affected need to be included in planning and delivery stages of rebuilding and development in conflict-affected contexts. The study researched this issue with a group of young children and their families living in a resettling and rebuilding post-conflict village in Sri Lanka. The research applied Honneth’s theory of recognition to investigate young children’s lived experiences of wellbeing in terms of care, rights and solidarity and matched these with the perspectives of caregivers, community leaders and service providers. The study made use of the Mosaic approach that included drawings, interviews, child-led tours, photography and narratives of young children along with interviews and focus group discussions with relevant adults. It was shown that multiple perspectives co-exist within the relatively small, contained context of the conflict-affected community. The study revealed differences in perspectives between groups of adults and between adults and young children. For example, the cohort of adult service providers cited gaps in parenting practices, community mobilisation, and community cohesion, and the cohort of community leaders identified gaps in external supports. Young children and their caregivers, on the other hand, reported positive aspects about the situation. In particular, young children displayed high levels of connectivity in the form of care and support within their families, and social connectedness and solidarity within the community. However, some discrepancies between children and families from different ethnic groups were noted. The study indicates that despite long-term conflict, displacement and concomitant disruptions in this rebuilding post-conflict context, the elements that support young children’s experiences of connectedness within family and community may have a protective element for children and families. Implications for ensuring the inclusion of multiple voices (including those of young children and their caregivers) in assessments of conflict-affected situations and for enhancing supports that contribute to critical components of ‘recognition’ are discussed.
title: ADCO, Ordre cistercien : comptes (1403-1423) (11 H 1161), f. 00087
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161), f. 00087, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
Noise reduction in diffusion MRI using non-local self-similar information in joint x âˆ’ q space
Creators: name: Shen, Dinggang
name: Yap, Pew-Thian
name: Wu, Yafeng
name: Chen, Geng
Publisher: name: Elsevier
Year: 2019

description: Diffusion MRI affords valuable insights into white matter microstructures, but suffers from low signal-to-noise ratio (SNR), especially at high diffusion weighting (i.e., b-value). To avoid time-intensive repeated acquisition, post-processing algorithms are often used to reduce noise. Among existing methods, non-local means (NLM) has been shown to be particularly effective. However, most NLM algorithms for diffusion MRI focus on patch matching in the spatial domain (i.e., x-space) and disregard the fact that the data live in a combined 6D space covering both spatial domain and diffusion wavevector domain (i.e., q-space). This drawback leads to inaccurate patch matching in curved white matter structures and hence the inability to effectively use recurrent information for noise reduction. The goal of this paper is to overcome this limitation by extending NLM to the joint x-q space. Specifically, we define for each point in the x-q space a spherical patch from which we extract rotation-invariant features for patch matching. The ability to perform patch matching across q-samples allows patches from differentially orientated structures to be used for effective noise removal. Extensive experiments on synthetic, repeated-acquisition, and HCP data demonstrate that our method outperforms state-of-the-art methods, both qualitatively and quantitatively.
Non-Maxwellian analysis of the transition-region line profiles observed by the Interface Region Imaging Spectrograph
Creators: name: Dudik, Jaroslav
name: Polito, Vanessa
name: Dzifcakova, Elena
name: Del Zanna, Giulio
name: Testa, Paola
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We investigate the nature of the spectral line profiles for transition region ions observed with the Interface Region Imaging Spectrograph (IRIS). In this context, we have analyzed an active-region observation performed by IRIS in its 1400 A spectral window. The transition-region lines are found to exhibit significant wings in their spectral profiles, which can be well-fitted with non-Maxwellian kappa-distribution. The fit with a kappa-distribution can perform better than a double Gaussian fit, especially for the strongest line, Si IV 1402.8 A. Typical values of $κ$ found are about 2, occurring in a majority of spatial pixels where the transition region lines are symmetric, i.e., the fit can be performed. Furthermore, all five spectral lines studied (from Si IV, O IV and S IV) appear to have the same FWHM irrespective of whether the line is an allowed or an intercombination transition. A similar value of kappa is obtained for the electron distribution by fitting of the line intensities relative to Si IV 1402.8 A, if photospheric abundances are assumed. The kappa-distributions however do not remove the presence of non-thermal broadening. Instead, they actually increase the non-thermal width. This is because for kappa-distributions the transition-region ions are formed at lower temperatures. The large observed non-thermal width lowers the opacity of the Si IV line sufficiently enough for this line to become optically thin.
description: The Astrophysical Journal, accepted
Additional file 1: of Effectiveness of a psycho-educational intervention to prevent postpartum parental distress and enhance infant well-being: study protocol of a randomized controlled trial
Creators: name: Missler, Marjolein
name: Roseriet Beijers
name: Denissen, Jaap
name: Straten, Annemieke Van
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist. (DOC 122 kb)
Precision neutrino experiments vs the Littlest Seesaw
Creators: name: Ballett, Peter
name: King, Stephen F.
name: Pascoli, Silvia
name: Prouse, Nick W.
name: Wang, TseChun
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We study to what extent upcoming precision neutrino oscillation experiments will be able to exclude one of the most predictive models of neutrino mass and mixing: the Littlest Seesaw. We show that this model provides a good fit to current data, predicting eight observables from two input parameters, and provide new assessments of its predictions and their correlations. We then assess the ability to exclude this model using simulations of upcoming neutrino oscillation experiments including the medium-distance reactor experiments JUNO and RENO-50 and the long-baseline accelerator experiments DUNE and T2HK. We find that an accurate determination of the currently least well measured parameters, namely the atmospheric and solar angles and the CP phase $δ$, provide crucial independent tests of the model. For $θ_{13}$ and the two mass-squared differences, however, the model's exclusion requires a combination of measurements coming from a varied experimental programme. Our results show that the synergy and complementarity of future experiments will play a vital role in efficiently discriminating between predictive models of neutrino flavour, and hence, towards advancing our understanding of neutrino oscillations in the context of the flavour puzzle of the Standard Model.
description: 27 pages, 13 figures
On the sustainability of a family planning program in Nigeria when funding ends
Creators: name: Guilkey, David K.
name: Ojogun, Osifo T.
name: Speizer, Ilene S.
name: Calhoun, Lisa M.
name: Escamilla, Veronica
name: Fasiku, David
name: Lance, Peter M.
Publisher: name: Public Library of Science (PLoS)
Year: 2019

description: Few studies have examined the sustainability of family planning program outcomes in the post-program period. This article presents the results of a natural experiment where the Nigerian Urban Reproductive Health Initiative Phase I programming ended in early 2015 and Phase II activities continued in a subset of cities. Using data collected in 2015 and 2017, we compare contraceptive ideation and modern family planning use in two cities: Ilorin where program activities concluded in 2015 and Kaduna where program activities continued. The results demonstrate that exposure to program activities decreased in Ilorin but for those individuals reporting continuing exposure, the effect size of exposure on modern family planning use remained the same and was not significantly different from Kaduna. Modern family planning use continued to increase in both cites but at a lower rate than during Phase I. The results are useful for designing family planning programs that sustain beyond the life of the program.
Combining symmetry collective states with coupled cluster theory: Lessons from the Agassi model Hamiltonian
Creators: name: Hermes, Matthew R.
name: Dukelsky, Jorge
name: Scuseria, Gustavo E.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The failures of single-reference coupled cluster for strongly correlated many-body systems is flagged at the mean-field level by the spontaneous breaking of one or more physical symmetries of the Hamiltonian. Restoring the symmetry of the mean-field determinant by projection reveals that coupled cluster fails because it factorizes high-order excitation amplitudes incorrectly. However, symmetry-projected mean-field wave functions do not account sufficiently for dynamic (or weak) correlation. Here we pursue a merger of symmetry projection and coupled cluster theory, following previous work along these lines that utilized the simple Lipkin model system as a testbed [J. Chem. Phys. 146, 054110 (2017)]. We generalize the concept of a symmetry-projected mean-field wave function to the concept of a symmetry projected state, in which the factorization of high-order excitation amplitudes in terms of low-order ones is guided by symmetry projection and is not exponential, and combine them with coupled cluster theory in order to model the ground state of the Agassi Hamiltonian. This model has two separate channels of correlation and two separate physical symmetries which are broken under strong correlation. We show how the combination of symmetry collective states and coupled cluster is effective in obtaining correlation energies and order parameters of the Agassi model throughout its phase diagram.
Additional file 8: Figure S4. of Cattle infection response network and its functional modules
Creators: name: Beiki, Hamid
name: Pakdel, Abbas
name: Ardeshir Javaremi
name: Masoudi-Nejad, Ali
name: Reecy, James
Publisher: name: figshare
Year: 2018
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Frequency of TOM connectivity in the network. (PDF 262Â kb)
Perspectives and experiences of Zambian pregnant and postpartum women receiving two intervention models to increase uptake of male partner HIV testing
Creators: name: Hazwela, Caroline
name: Mutale, Wilbroad
name: Matenga, Tulani Francis L.
name: Freeborn, Kellie
name: Chi, Benjamin H.
name: Lusaka, Mildred
name: Rosenberg, Nora E.
name: Maman, Suzanne
name: Kamat, Aditi
name: Kumwenda, Andrew
name: Namukanga, Nachizya Edith
name: Mweemba, Oliver
Publisher: name: Taylor & Francis
Year: 2023

description: This study explored the experiences of pregnant women who received two intervention models for increasing uptake of male partner HIV testing in antenatal settings. As part of a randomised trial, we interviewed twenty participants who received partner notification services only while 22 received the partner notification plus HIV self-testing. Thematic analysis was used to analyse the data. Partner notification services helped to initiate discussions of HIV testing with partners, influence partners to undergo testing, and encouraged disclosure of HIV status. Some women experienced difficulties engaging partners due to fear of their partner's reaction. Some partners were unable to test due to time constraints. The partner notification plus HIV self-testing intervention, stimulated discussion about HIV testing; facilitated testing for men at their convenience; addressed privacy/confidentiality, and stigma concerns; and provided the opportunity to disclose HIV status. Some women feared disclosure and retribution in case of discordance results. There were also challenges with men making follow-ups for confirmatory HIV tests. The addition of HIV self-test kits to partner notification services can expand HIV testing services to male partners, including those of HIV-negative women. Additional efforts are needed to link men to appropriate HIV prevention, care, and treatment services.
API Security through Contract-Driven Programming.
Creators: name: Vesey, Alexander
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: Software Engineering

description: According to MITRE, the most common form of API (application programming interface) misuse occurs when the caller does not honor its end of a contract.  In the  context of this article, a "contract" refers to a formal, precise agreement that outlines the expected behaviors, inputs, outputs, and side effects that an API guarantees to any caller, ensuring that both the API and its clients adhere to specified constraints and usages. This concept is crucial in preventing misuse by clearly defining the  boundaries and requirements for both parties involved in the interaction. This blog post explores contract programming and specifically how that applies to the building, maintenance, and security of APIs.
Experiences of school choice and change for mothers of students diagnosed with autism
Creators: name: Lilley, Rozanna
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This dissertation investigates the experiences of 22 mothers whose children diagnosed with autism were transitioning to school in Sydney, Australia. Qualitative interviews were conducted over three years (2009-2011) focusing on maternal experiences of school choice and change in the early years of formal education. Thematic narrative analysis of the interview transcripts (62 in total) is used to explore ongoing societal processes of stigmatisation and exclusion that shapes the lives of these families. A focus on maternal identity and gendered moralities underpins the analysis. Overall the six publications that comprise the core of this dissertation point to the constraints and dilemmas surrounding primary school placement and an ongoing drift towards segregated classrooms, especially for students diagnosed with both autism and an intellectual disability. The systemic failures to meet the promise of policies of school inclusion are demonstrated at the level of everyday practices by school gatekeepers, educators and bureaucrats. A variety of maternal tactics are deployed to manoeuvre and negotiate within an education field largely defined by professional and institutional strategies. The dissertation is interdisciplinary, drawing on sociology, anthropology and critical disability studies. Theoretically the argument moves in two directions. Firstly, Goffman's conceptualisation of 'courtesy' stigma is reframed to more specifically account for the felt experiences of mothers. Secondly, maternal engagement with various forms of knowledge, both expert (professional guidance) and lay (rumour), is highlighted. Stigma and knowledge negotiation are intertwined in ongoing projects of school choice and school change which, in turn, shape and challenge identity at particular moments of maternal and student careers. School change narratives are used to invert the usual emphasis on the deficits of students diagnosed with autism focusing, instead, on maternal perceptions of the disabling practices of educators. The dissertation concludes with a case for conceptualising these widespread practices as Autism Inclusion Disorder.