cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Addition of dimethyl phosphite to N,N'-dialkyl- and -diaryl terephthalaldimines and its stereochemistry contrary to behavior of other analogues
Creators: name: Jarosław Lewkowski
name: Ignaczak, Anna
name: Rafał Karpowicz
name: Obiedzińska, Justyna
name: Rodriguez-Moya, Maria
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: The addition of dimethyl phosphite to N,N'-terephthalylidene-alkyl- (or aryl-) amines resulted in new tetramethyl 1,4-phenylene-bis-(N-alkylaminomethyl)-phosphonates in moderate yields. The stereochemical behavior of these reactions was studied by NMR, demonstrating that the reactions lead to the formation of both possible diastereomeric forms from 1:1 to 1:2 ratios. This was unexpected considering that previously investigated additions of diethyl, dibenzyl, and diphenyl phosphites to terephthalaldimines were diastereoselective up to 100%. Attempts were made to find reasonable explanation for the phenomenon using semi-empirical and DFT calculations.
Predominance of Alcohol and Illicit Drugs among Traffic Accidents Fatalities in an Urban Area of Brazil
Creators: name: Fabrício Souza Pelição
name: Peres, Mariana Dadalto
name: Jauber Fornaciari Pissinate
name: Paula, Daniela Mendes Louzada De
name: Faria, Maria Das Graças Corrêa De
name: Nakamura-Palacios, Ester Miyuki
name: Martinis, Bruno Spinosa De
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Objective: Determine the prevalence of alcohol and illicit drug use among victims of fatal traffic accidents in the Metropolitan Region of Vitória, ES – Brazil, during the period of 2011–2012. Methods: Blood samples were collected and analyzed for the presence of drugs from 391 deceased victims of traffic crashes that occurred in the Metropolitan Region of Vitória, ES – Brazil. The victims were constituted of drivers, passengers and pedestrians. Sociodemographic variables such as age, gender, day of the week and period of the year in which the accidents happened were recorded. The analyses were performed by a gas chromatography-flame ionization method for alcohol, and by a gas chromatography-mass spectrometer method for amphetamines, cocaine and cannabis. Results: 44.8% (n = 175) of all cases were positive for alcohol and/or illicit drugs. The detection of alcohol and/or drugs was more frequent in young males, aged 17 to 34, whose samples were positive in 46.8% of cases. Small differences among drivers, passengers and pedestrians were observed (drivers = 45.9%, passengers = 46.4% and pedestrians = 45.6%). In general, the most prevalent drug was alcohol, with 141 positive cases (36.1%), followed by cocaine, with 47 positive cases (12%). Amphetamines and cannabis had positivity rates of 4.1% and 4.3%, with 16 and 17 positive cases, respectively. The combined use of alcohol and other drugs was found in 36 cases (9.2%). Crack cocaine use was observed in 27.7% of the positive cases for cocaine. Conclusions: For the effective reduction of traffic accidents related to driving under influence of drugs (DUID), we suggest the intensification of enforcement actions against the use of alcohol by drivers, the definition of which illicit drugs should be surveyed as well the cut-off values, the promotion of changing legislation to obligate drivers to provide samples for toxicological testing, the establishment of public information programs and specific actions aimed at young drivers to promote behavioral changes.
Addition of Dimethyl Phosphite to N,N'-dialkyl- and -diaryl Terephthalaldimines and Its Stereochemistry Contrary to Behavior of Other Analogues
Creators: name: Jarosław Lewkowski
name: Ignaczak, Anna
name: Rafał Karpowicz
name: Obiedzińska, Justyna
name: Rodriguez-Moya, Maria
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: The addition of dimethyl phosphite to N,N'-terephthalylidene-alkyl- (or aryl-) amines resulted in new tetramethyl 1,4-phenylene-bis-(N-alkylaminomethyl)-phosphonates in moderate yields. The stereochemical behaviour of these reactions was studied by NMR demonstrating, that the reactions lead to the formation of both possible diastereomeric forms in 1:1 up to 1:2 ratios. This was unexpected considering that previously investigated additions of diethyl, dibenzyl and diphenyl phosphites to terephthalaldimines were diastereoselective up to 100%. Attempts were made to find reasonable explanation for the phenomenon using semi-empirical and DFT calculations.
Repeatability of a dynamic rollover test system
Creators: name: Seppi, Jeremy
name: Toczyski, Jacek
name: Crandall, Jeff R.
name: Kerrigan, Jason
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Objective: The goal of this study was to characterize the rollover crash and to evaluate the repeatability of the Dynamic Rollover Test System (DRoTS) in terms of initial roof-to-ground contact conditions, vehicle kinematics, road reaction forces, and vehicle deformation. Methods: Four rollover crash tests were performed on 2 pairs of replicate vehicles (2 sedan tests and 2 compact multipurpose van [MPV] tests), instrumented with a custom inertial measurement unit to measure vehicle and global kinematics and string potentiometers to measure pillar deformation time histories. The road was instrumented with load cells to measure reaction loads and an optical encoder to measure road velocity. Laser scans of pre- and posttest vehicles were taken to provide detailed deformation maps. Results: Initial conditions were found to be repeatable, with the largest difference seen in drop height of 20 mm; roll rate, roll angle, pitch angle, road velocity, drop velocity, mass, and moment of inertia were all 7% different or less. Vehicle kinematics (roll rate, road speed, roll and pitch angle, global Z′ acceleration, and global Z′ velocity) were similar throughout the impact; however, differences were seen in the sedan tests because of a vehicle fixation problem and differences were seen in the MPV tests due to an increase in reaction forces during leading side impact likely caused by disparities in roll angle (3° difference) and mass properties (2.2% in moment of inertia [MOI], 53.5 mm difference in center of gravity [CG] location). Conclusions: Despite those issues, kinetic and deformation measures showed a high degree of repeatability, which is necessary for assessing injury risk in rollover because roof strength positively correlates with injury risk (Brumbelow 2009). Improvements of the test equipment and matching mass properties will ensure highly repeatable initial conditions, vehicle kinematics, kinetics, and deformations.
Misuse of booster cushions among children and adults in Shanghai—an observational and attitude study during buckling up
Creators: name: Bohman, Katarina
name: Jorlöv, Sofia
name: Shengqi Zhou
name: Cloud Zhao
name: Sui, Bo
name: Chengkai Ding
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective: Traffic crashes are one of the leading causes of fatalities among Chinese children. Booster cushion usage in China is low, and there are no studies showing how a population with limited experience handles booster cushions during buckling up. The purpose of this study was to evaluate the handling of and explore the attitudes toward booster cushions among children, parents, and grandparents in Shanghai. Methods: An observational study including a convenience sample of 254 children aged 4–12 years was conducted in 2 passenger cars at a shopping center in Shanghai. Parents, grandparents, or the children themselves buckled up the child on 2 types of booster cushions, a 2-stage integrated booster cushion (IBC) and an aftermarket booster cushion (BC). The test participants were observed during buckling up, first without and then with instructions. The test leaders conducted structured interviews. Results: Ninety-eight percent of the uninstructed participants failed to buckle up without identified misuse on the aftermarket booster cushion and 31% of those uninstructed on the integrated booster cushion. The majority of misuse was severe, including placing the belt behind the arm and the lap belt routing above the guiding loops. Instruction reduced misuse to 58% (BC) and 12% (IBC), respectively, and, in particular, severe misuse. Some misuse was related to limited knowledge of how to buckle up on the booster cushion, and some misuse was intentional in order to reduce discomfort. The participants, both children and adults, reported that they preferred the IBC due to good comfort and convenience. Safety was reported as the main reason for adults using booster cushions in general, whereas children reported comfort as the most important motivation. Conclusions: Education is needed to ensure frequent and correct use of booster cushions in China and to raise safety awareness among children and adults. Furthermore, it is important that the booster cushions offer intuitively correct usage to a population with limited experience of booster cushions. This is the first study published on the handling of and attitude toward booster cushions after child restraints laws were introduced in Shanghai 2014.
Thematic Summary 7th Review Cycle of the Treaty on the Non Proliferation of Nuclear Weapons, 2005 Review Conference
Creators: name: Non-Aligned Movement
Publisher: name: Non-Aligned Movement
Year: 2005

description: Thematic Summary of the Working Papers Submitted by the Group of Non -Aligned
States Parties of the 7th Review Cycle of the Treaty on the Non -Proliferation of Nuclear
Weapons,  2005  Review Conference

Disarmament

Nuclear Weapon
Convention
(NPT/CONF.2005/WP.8, Para 34)  The States parties call upon the
Conference on Disarmament to establish, as soon as possible and as the
highest priority, an ad hoc committee on nuclear disarmament, taking
into account all proposals that hav
Thematic Summary 10th Review Cycle of the Treaty on the Non Proliferation of Nuclear Weapons, 2018 Preparatory Committee
Creators: name: Non-Aligned Movement
Publisher: name: Non-Aligned Movement
Year: 2018

description: Thematic Summary of the Working Papers Submitted by the Group of Non -Aligned
States Parties of the 10th Review Cycle of the Treaty on the Non -Proliferation of Nuclear
Weapons,  2018 Preparatory Committee

Disarmament

Nuclear Weapon
Convention
(NPT/CONF.2020/PC.II/WP.15, Para 2) In that context, negotiations
on a comprehensive nuclear weapons convention that includes a phased
programme and a specified time frame  for the complete elimination of
nuclear weapons are needed.
ABC News/Washington Post Poll: Government Shutdown
Creators: name: ABC News
name: Washington Post
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: Responsible for federal government shutdown (1); inconvenienced by shutdown (1); problem if shutdown continues (1); wall along United States border with Mexico (1); compromise on border wall to end shutdown (2); Trump using emergency powers to build a wall along border with Mexico (1); illegal immigration across United States border with Mexico (1).
Repeatability of a dynamic rollover test system
Creators: name: Seppi, Jeremy
name: Toczyski, Jacek
name: Crandall, Jeff R
name: Kerrigan, Jason
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Objective: The goal of this study was to characterize the rollover crash and to evaluate the repeatability of the Dynamic Rollover Test System (DRoTS) in terms of initial roof-to-ground contact conditions, vehicle kinematics, road reaction forces and vehicle deformation. Methods: Four rollover crash tests were performed on two pairs of replicate vehicles (two sedan tests and two compact multi-purpose van (MPV) tests), instrumented with a custom inertial measurement unit to measure vehicle and global kinematics and string potentiometers to measure pillar deformation time histories. The road was instrumented with load cells to measure reaction loads and an optical encoder to measure road velocity. Laser scans of pre- and post-test vehicles were taken to provide detailed deformation maps. Results: Initial conditions were found to be repeatable, with the largest difference seen in drop height of 20mm while roll rate, roll angle, pitch angle, road velocity, drop velocity, mass, and moment of inertia were all 7% different or less. Vehicle kinematics (roll rate, road speed, roll and pitch angle, global Z' acceleration, and global Z' velocity) were similar throughout the impact, however differences were seen in the sedan tests because of a vehicle fixation problem and differences were seen in the MPV tests due to an increase in reaction forces during leading side impact likely caused by disparities in roll angle (3° difference) and mass properties (2.2% in MOI, 53.5mm difference in CG location). Conclusions: Despite those issues, kinetic and deformation measures showed a high degree of repeatability which is necessary for assessing injury risk in rollover as roof strength positively correlates with injury risk (Brumbelow, 2009). Improvements of the test equipment and matching mass properties will ensure highly repeatable initial conditions, vehicle kinematics, kinetics, and deformations.
Thematic Summary 10th Review Cycle of the Treaty on the Non Proliferation of Nuclear Weapons, 2019 Preparatory Committee
Creators: name: Non-Aligned Movement
Publisher: name: Non-Aligned Movement
Year: 2019

description: Thematic Summary of the Working Papers Submitted by the Group of Non -Aligned
States Parties of the 10th Review Cycle of the Treaty on the Non -Proliferation of Nuclear
Weapons,  2019  Preparatory Committee

Disarmament

Nuclear Weapon
Convention
(NPT/CONF.2020/PC.III/WP.10, Para 2) In that context,
negotiations on a comprehensive nuclear weapons convention that
includes a phased programme and a specified time frame  for the
complete elimination of nuclear weapons are needed.
Misuse of booster cushions among children and adults in Shanghai - an observational and attitude study during buckling up
Creators: name: Bohman, Katarina
name: JorlÖv, Sofia
name: Shengqi Zhou
name: Cloud Zhao
name: Sui, Bo
name: Chengkai Ding
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective: Traffic crashes are one of the leading causes of fatalities among Chinese children. Booster cushion usage in China is low, and there are no studies showing how a population with limited experience handles booster cushions during buckling up. The purpose of this study was to evaluate the handling of and explore the attitudes toward, booster cushions among children, parents and grandparents in Shanghai. Methods: An observational study including, a convenience sample of 254 children aged 4–12 years, was conducted in two passenger cars at a shopping center in Shanghai. Parents, grandparents, or the children themselves, buckled up the child on two types of booster cushions; a two-stage integrated booster cushion (IBC), and an aftermarket booster cushion (BC). The test participants were observed during buckling up, first without and then with instructions. The test leaders conducted structured interviews. Results: 98% of the uninstructed participants failed to buckle up without identified misuse on the aftermarket booster cushion, and 31% of those uninstructed on the integrated booster cushion. The majority of misuse was severe, including placing the belt behind the arm, and the lap belt routing above the guiding loops. Instruction reduced misuse to 58% (BC), and 12% (IBC), respectively, and, in particular, severe misuse. Some misuse was related to limited knowledge of how to buckle up on the booster cushion, and some misuse was intentional in order to reduce discomfort. The participants, both children and adults, reported they preferred the IBC due to good comfort and convenience. Safety was reported as the main reason for adults using booster cushions in general, while children reported comfort as the most important motivation. Conclusions: Education is needed to ensure frequent and correct use of booster cushions in China, and to raise safety awareness among children and adults. Furthermore, it is important that the booster cushions offer intuitively correct usage to a population with limited experience of booster cushions. This is the first study published on the handling of and attitude toward booster cushions after child restraints laws were introduced in Shanghai 2014.
Motorcycle fuel tanks and pelvic fractures: A motorcycle fuel tank syndrome
Creators: name: Meredith, Lauren
name: Baldock, Matthew
name: Fitzharris, Michael
name: Duflou, Johan
name: Nevo, Ross Dal
name: Griffiths, Michael
name: Brown, Julie
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Objective: Pelvic injuries are a serious and commonly occurring injury to motorcycle riders involved in crashes, yet there has been limited research investigating the mechanisms involved in these injuries. This study aimed to investigate the mechanisms involved in pelvic injuries to crashed motorcyclists. Method: This study involved in-depth crash investigation and 2 convenience-based data sets were used. These data sets investigated motorcycle crashes in the Sydney, Newcastle, and Adelaide regions. Participants included motorcycle riders who had crashed either on a public road or private property within the study areas. The mechanism of injury and the type of injuries were investigated. Results: The most frequent cause of pelvic injuries in crashed motorcyclists was due to contact with the motorcycle fuel tank during the crash (85%). For riders who had come into contact with the fuel tank, the injury types were able to be grouped into 3 categories based on the complexity of the injury. The complexity of the injury appeared to increase with impact speed but this was a nonsignificant trend. The pelvic injuries that did not occur from contact with the fuel tank in this sample differed in asymmetry of loading and did not commonly involve injury to the bladder. They were commonly one-sided injuries but this differed based on the point of loading; however, a larger sample of these injuries needs to be investigated. Conclusion: Overall improvements in road safety have not been replicated in the amelioration of pelvic injuries in motorcyclists and improvements in the design of crashworthy motorcycle fuel tanks appear to be required.
Analyzing the relationships between travel mode indicators and the number of passenger transport fatalities at the city level
Creators: name: Asadi-Shekari, Zohreh
name: Moeinaddini, Mehdi
name: Sultan, Zahid
name: Shah, Muhammad Zaly
name: Amran Hamzah
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Objective: A number of efforts have been conducted on travel behavior and transport fatalities at the neighborhood or street level, and they have identified different factors such as roadway characteristics, personal indicators, and design indicators related to transport safety. However, only a limited number of studies have considered the relationship between travel behavior indicators and the number of transport fatalities at the city level. Therefore, this study explores this relationship and how to fill the mentioned gap in current knowledge. Method: A generalized linear model (GLM) estimates the relationships between different travel mode indicators (e.g., length of motorway per inhabitants, number of motorcycles per inhabitant, percentage of daily trips on foot and by bicycle, percentage of daily trips by public transport) and the number of passenger transport fatalities. Because this city-level model is developed using data sets from different cities all over the world, the impacts of gross domestic product (GDP) are also included in the model. Conclusions: Overall, the results imply that the percentage of daily trips by public transport, the percentage of daily trips on foot and by bicycle, and the GDP per inhabitant have negative relationships with the number of passenger transport fatalities, whereas motorway length and the number of motorcycles have positive relationships with the number of passenger transport fatalities.
Analysing the relationships between travel mode indicators and the number of passenger transport fatalities at the city level
Creators: name: Asadi-Shekari, Zohreh
name: Moeinaddini, Mehdi
name: Sultan, Zahid
name: Shah, Muhammad Zaly
name: Amran Hamzah
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Objective: A number of efforts have been conducted on travel behaviour and transport fatalities at the neighbourhood or street level, and they have identified different factors such as roadway characteristics, personal indicators and design indicators related to transport safety. However, only a limited number of studies have considered the relationship between travel behaviour indicators and the number of transport fatalities at the city level. Therefore, this study explores this relationship and how to fill the mentioned gap in current knowledge. Method: A generalized linear model (GLM) estimates the relationships between different travel mode indicators (e.g., length of motorway per inhabitants, number of motorcycles per inhabitants, percentage of daily trips on foot and by bicycle, percentage of daily trips by public transport) and the number of passenger transport fatalities. Because this city-level model is developed using data sets from different cities all over the world, the impacts of GDP are also included in the model. Conclusions: Overall, the results imply that the percentage of daily trips by public transport, the percentage of daily trips on foot and by bicycle and the GDP per inhabitant have negative relationships with the number of passenger transport fatalities, while the motorway's length and the number of motorcycles have positive relationships with the number of passenger transport fatalities.
Thematic Summary 6th Review Cycle of the Treaty on the Non Proliferation of Nuclear Weapons, 2000 Review Conference
Creators: name: Non-Aligned Movement
Publisher: name: Non-Aligned Movement
Year: 2000

description: Thematic Summary of the Working Papers Submitted by the Group of Non -Aligned
States Parties of the 6th Review Cycle of the Treaty on the Non -Proliferation of Nuclear
Weapons,  2000  Review Conference

Disarmament

Nuclear Weapon
Convention
(NPT/CONF.200 0/WP.18, Para 31)  The States Parties call upon the
Conference on Disarmament to establish an ad hoc committee on
nuclear disarmament taking into account all proposals which have been
submitted by members of the Group of 21,
Thematic Summary 6th Review Cycle of the Treaty on the Non Proliferation of Nuclear Weapons, 1999 Preparatory Committee
Creators: name: Non-Aligned Movement
Publisher: name: Non-Aligned Movement
Year: 1999

description: Thematic Summary of the Working Papers Submitted by the Group of Non -Aligned
States Parties of the 6th Review Cycle of the Treaty on the Non -Proliferation of Nuclear
Weapons,  1999 Preparatory Committee

Disarmament

Nuclear Weapon
Convention
(NPT/CONF.2000/PC.III/WP.1, Para 27)  The States Parties call
upon the Conference on Disarmament to establish an ad hoc committee
on nuclear disarmament taking into account all proposals which have
been submitted by members of the Group
MYC and PVT1 synergize to regulate RSPO1 levels in breast cancer
Creators: name: Sarver, Aaron L.
name: Murray, Colin D.
name: Temiz, Nuri A.
name: Yeun-Yi Tseng
name: Anindya Bagchi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Developmental Biology
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: Copy number gain of the 8q24 region including the v-myc avian myelocytomatosis viral oncogene homolog (MYC) oncogene has been observed in many different cancers and is associated with poor outcomes. While the role of MYC in tumor formation has been clearly delineated, we have recently shown that co-operation between adjacent long non-coding RNA plasmacytoma variant transcription 1 (PVT1) and MYC is necessary for tumor promotion. Chromosome engineered mice containing an increased copy of Myc-Pvt1 (Gain Myc-Pvt1) accelerates mammary tumors in MMTV-Neu mice, while single copy increase of each is not sufficient. In addition, mammary epithelium from the Gain Myc-Pvt1 mouse show precancerous phenotypes, notably increased DNA replication, elevated ΥH2AX phosphorylation and increased ductal branching. In an attempt to capture the molecular signatures in pre-cancerous cells we utilized RNA sequencing to identify potential targets of supernumerary Myc-Pvt1 cooperation in mammary epithelial cells. In this extra view we show that an extra copy of both Myc and Pvt1 leads to increased levels of Rspo1, a crucial regulator of canonical β-catenin signaling required for female development. Human breast cancer tumors with high levels of MYC transcript have significantly more PVT1 transcript and RSPO1 transcript than tumors with low levels of MYC showing that the murine results are relevant to a subset of human tumors. Thus, this work identifies a key mechanism in precancerous and cancerous tissue by which a main player in female differentiation is transcriptionally activated by supernumerary MYC and PVT1, leading to increased premalignant features, and ultimately to tumor formation.
Nonoxidative removal of organics in the activated sludge process
Creators: name: Modin, Oskar
name: Persson, Frank
name: Britt-Marie Wilén
name: Hermansson, Malte
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Cell Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The activated sludge process is commonly used to treat wastewater by aerobic oxidation of organic pollutants into carbon dioxide and water. However, several nonoxidative mechanisms can also contribute to removal of organics. Sorption onto activated sludge can remove a large fraction of the colloidal and particulate wastewater organics. Intracellular storage of, e.g., polyhydroxyalkanoates (PHA), triacylglycerides (TAG), or wax esters can convert wastewater organics into precursors for high-value products. Recently, several environmental, economic, and technological drivers have stimulated research on nonoxidative removal of organics for wastewater treatment. In this paper, we review these nonoxidative removal mechanisms as well as the existing and emerging process configurations that make use of them for wastewater treatment. Better utilization of nonoxidative processes in activated sludge could reduce the wasteful aerobic oxidation of organic compounds and lead to more resource-efficient wastewater treatment plants.
title: 01_2704
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
The raw LC–MS/MS data for identifying secretory acetylated proteins of Fusarium oxysporum f. sp. lycopersici
Creators: name: Li, Jingtao
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310702
subject: Infectious agents

description: Secretome-Wide Analysis of Lysine Acetylation in Fusarium oxysporum f. sp. lycopersici
Thematic Summary 6th Review Cycle of the Treaty on the Non Proliferation of Nuclear Weapons, 1997 Preparatory Committee
Creators: name: Non-Aligned Movement
Publisher: name: Non-Aligned Movement
Year: 1997

description: Thematic Summary of the Working Papers Submitted by the Group of Non -Aligned
States Parties of the 6th Review Cycle of the Treaty on the Non -Proliferation of Nuclear
Weapons,  1997  Preparatory Committee

Disarmament

Nuclear Weapon
Convention
(NPT/CONF.2000/PC.I/WP.10, Para 11)  States parties should agree
on a recommendation to the Conference on Disarmament to establish,
on a priority basis, an ad hoc committee on nuclear disarmament to
commence negotiations on a phased pr
Non-Oxidative Removal of Organics in the Activated Sludge Process
Creators: name: Modin, Oskar
name: Persson, Frank
name: Britt-Marie Wilen
name: Hermansson, Malte
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The activated sludge process is commonly used to treat wastewater by aerobic oxidation of organic pollutants into carbon dioxide and water. However, several non-oxidative mechanisms can also contribute to removal of organics. Sorption onto activated sludge can remove a large fraction of the colloidal and particulate wastewater organics. Intracellular storage of e.g. polyhydroxyalkanoates (PHA), triacylglycerides (TAG), or wax esters can convert wastewater organics into precursors for high-value products. Recently, several environmental, economic, and technological drivers have stimulated research on non-oxidative removal of organics for wastewater treatment. In this paper, we review these non-oxidative removal mechanisms as well as the existing and emerging process configurations that make use of them for wastewater treatment. Better utilization of non-oxidative processes in activated sludge could reduce the wasteful aerobic oxidation of organic compounds and lead to more resource-efficient wastewater treatment plants.
title: 03_0611
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Assessing the Impacts of Irrigation Systems on Food Security in Southwestern Nigeria
Creators: name: Fidelis Ajibade
Publisher: name: figshare
Year: 2016
Subjects: subject: 99901 Agricultural Engineering
subject: FOS: Other engineering and technologies
subject: 90599 Civil Engineering not elsewhere classified
subject: FOS: Civil engineering
subject: 90801 Food Chemistry and Molecular Gastronomy (excl. Wine)
subject: 90802 Food Engineering
subject: 90803 Food Nutritional Balance
subject: 90804 Food Packaging, Preservation and Safety
subject: 90805 Food Processing
subject: 90899 Food Sciences not elsewhere classified
subject: 91010 Packaging, Storage and Transportation (excl. Food and Agricultural Products)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 91503 Engineering Practice
subject: 91504 Fluidisation and Fluid Mechanics
subject: 99999 Engineering not elsewhere classified

description: Irrigation is considered an essential factor for agriculture and food security and therefore this study focused on the assessment of major systems and challenges of irrigation practices in Ondo and Ogun States, Nigeria. Structured questionnaire were administered to farmers in generating information used. Demography of the farmers showed that majority of them was males (84%) while only (11%) female were from Ogun state. Most respondents (89%) were aged 45 years and above while the least-represented age group was less than 35 years. Educationally, over 63 % had formal education out of which only 5 % of respondents had primary education. The response showed that majority of the respondents in the study area practiced surface irrigation which accounted for 57% of the types of irrigation considered. Sprinkler (26%) and drip (13%) irrigation respectively were practiced by the farmers. However, lack of technical knowhow, inadequate knowledge of crop water requirements and irrigation scheduling strategies were the greatest challenges to sustainable small-scale irrigation in the study areas.
Thematic Summary 10th Review Cycle of the Treaty on the Non Proliferation of Nuclear Weapons, 2022 Review Conference
Creators: name: Non-Aligned Movement
Publisher: name: Non-Aligned Movement
Year: 2022

description: Thematic Summary of the Working Papers Submitted by the Group of Non -Aligned
States Parties of the 10th Review Cycle of the Treaty on the Non -Proliferation of Nuclear
Weapons, 2022 Review Conference

Disarmament

Nuclear Weapon
Convention
(NPT/CONF.2020/WP.20, Para 16)  In this context, the Group of
Non-Aligned States Parties to the Treaty welcomes the adoption by the
General Assembly of resolutions 68/32, 70/34, 71/71, 72/251, 73/40
and 74/54 entitled "Follow -up to the 201
Family peer advocates : strengthening the alliance among high need families and mental health providers
Creators: name: Jamison, Jesslyn M.
name: 0000-0003-2628-9378
Publisher: name: The University of Texas at Austin
Year: 2019
Subjects: Family peer advocate
Child mental health
Therapeutic alliance
Child welfare

description: Family Peer Advocates (FPAs) are one type of peer-to-peer support proposed to help address unmet mental health needs of children and families and augment mental health treatment. This study examined whether FPA support predicted child mental health symptoms and therapeutic alliance with mental health providers at the end of mental health treatment for a sample of families in a larger effectiveness trial (N = 114) who elected to have support from a FPA (n= 76) and families who did not (n = 38). Study participants were primarily Caucasian/European(79.8%) and Child Welfare referred (75%). Additionally, this study examined whether being referred for treatment by Child Welfare moderated the relationship between FPA support and changes in child symptoms and parental therapeutic alliance with a mental health provider. Results indicated that FPA support did not predict child symptoms at end of outpatient mental health treatment or parent rating of therapeutic alliance in the sample as a whole. Child Welfare referral status moderated the relationship between FPA support and parental ratings of therapeutic alliance. Support from an FPA was a significant predictor of parental ratings of therapeutic alliance for families who were referred to treatment by Child Welfare (b = 3.88, t = 2.48, p = 0.015, ηp2 = .077), suggesting that FPA support may augment the therapeutic alliance with outpatient mental health provider for highly strained families. Keywords: Family Peer Advocate; Child Mental Health; Therapeutic Alliance; Child Welfare
Do we need to use hazardous chemicals in society? The implementation of the "Essential-Use" Concept
Creators: name: Figuière, Romain
Publisher: name: Zenodo
Year: 2025

description: Chemical legislation serves as an important regulatory tool to protect human health and the environment from the risksposed by substances of concern. Discussions at the EU level have focused on implementing the “essential-use” conceptin chemical regulations to improve their efficiency. In short, a use of a substance of concern should be permitted onlyif it is deemed “essential” – that is, if it is necessary for health, safety, or critical for the functioning of society, and thatthere is no safer alternative available. Although the European Commission recently published guiding criteria to considerfor implementing the “essential-use” concept as a tool to guide decision-making, more work is needed to investigate itspractical implementation.

By taking the examples of uses of per- and polyfluoroalkyl substances (PFAS), three persistent, mobile,and toxic (PMT) substances (i.e. allura red, benzophenone-4, and climabazole), and microplastics,this thesis aims to determine the type and amount of information needed to make a proper essentiality assessment. Thefunctional substitution approach was followed to determine the chemical functions provided by the case study substancesin their respective uses, and how these functions are linked with the services the substances provide in the end product.Based on this information, one use of allura red, and two uses of microplastics were deemed “nonessential”as the functions delivered by the substances are not necessary for the technical performance of the end product.Existing alternatives assessment frameworks were followed to identify, evaluate, and compare potential alternatives to thesubstances of interest to determine if suitable alternatives were available for the uses being considered. Suitable and saferalternatives could be identified for 28 uses of PFAS, for all uses of allura red, benzophenone-4, andclimbazole, and for seven uses of microplastics, which were deemed “non-essential”.

This thesis also evaluates how the “essential-use” concept differs from current chemical legislation, and the implicationsof implementing such a concept to guide decision-making by taking the examples of the Stockholm Convention andthe REACH Regulation. The analysis suggests that no fundamental changes are needed in regulatory requirements toimplement the “essential-use” concept as authorities already have the capacity to gather the relevant information neededto determine if a use is (non-)essential. However, good cooperation with industry throughout the value chain is necessaryfor the competent authorities to properly understand the true purpose a substance of concern serves in the end product. Overall, the results suggest that the “essential-use” concept can be a valuable tool which presents the potentialto speed-up the decision-making by focusing on identifying the non-essential uses of substances of concern.

The thesis can also be found here

https://urn.kb.se/resolve?urn=urn%3Anbn%3Ase%3Asu%3Adiva-238367
Gamifying GARR with Network Invaders
Creators: name: Bertazzon, Elis
name: Trotto, Erika
Publisher: name: Zenodo
Year: 2024
Subjects: networking
communications
GARR

description: This presentation was delivered at the meeting of the Special Interest Group on Marketing and Communications held in Ljubljana, Slovenia on March 5-6, 2024 hosted by Arnes.

This presentation introduced the innovative idea of using videogames to promote the NREN's activities and explain the network.
Evaluation of Biogas Production from the Digestion and Co-Digestion of Animal Waste, Food Waste and Fruit-Waste
Creators: name: Fidelis Ajibade
Publisher: name: figshare
Year: 2016
Subjects: subject: 90599 Civil Engineering not elsewhere classified
subject: FOS: Civil engineering
subject: 90607 Power and Energy Systems Engineering (excl. Renewable Power)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 90608 Renewable Power and Energy Systems Engineering (excl. Solar Cells)
subject: 90701 Environmental Engineering Design
subject: FOS: Environmental engineering
subject: 90702 Environmental Engineering Modelling
subject: 90703 Environmental Technologies
subject: 90799 Environmental Engineering not elsewhere classified
subject: 91305 Energy Generation, Conversion and Storage Engineering
subject: FOS: Mechanical engineering
subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: The increased use of fossil fuels for energy consumption has causesenvironmental problems both locally and globally. The study investigates the anaerobicdigestion in the production of biogas a renewable energy from the digestion and co-digestionof three different types of biodegradable wastes (cow dung, fruit waste and food waste) as analternative for fossil fuels for energy consumption. This was carried out using a 25 Litrescapacity plastic keg prototype biogas plant, constructed to investigate the anaerobicdigestion in generating biogas. The experiment was batch operated and daily gas yield fromthe plant was monitored for 30 days. The slurry temperature and pH were also monitoredand presented. The digester was charged with these wastes in the ratio of 1:1, of waste towater respectively. The mesophilic temperatures range attained within the testing periodwere 25 - 28.4 and a slurry temperature range of 24.4 -28.4 . The result obtainedfrom the biogas production showed that the co-digestion of cow dung and food wasteproduced the highest biogas of 164.8%, followed by the co-digestion of the three waste (cowdung, fruit waste and food waste) which has a percentage of 91.0%, co-digestion of cow dungand fruit waste (83.9%), cow dung of 79.8%, food waste of 77.4% and fruit waste of 76.4%within this retention period. During the digestion period, the volume of biogas productionand the changes in pH indicate that the pH decreases as the retention period increases. Theseresults showed that co-digestion wastes produce more biogas than when the wastes areordinarily used for biogas production. The study recommends that biogas is not just arenewable energy source but also an appropriate way of managing waste, having potential toreplace fossil fuel.