cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Analytical regularisation for confined quantum fields between parallel surfaces
Creators: name: Santos, F C
name: Tort, A C
name: Elizalde, E
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We review a simple technique for evaluating the vacuum energy stemming from non-trivial boundary conditions and review results for the Casimir energy of a massive fermionic field confined in a d+1-dimensional slab-bag and the effect of a uniform magnetic field on the vacuum energy of confined massive bosonic and fermionic fields. New results concerning the Casimir energy and the evaluation of the rate of creation of quanta in kappa-deformed theories are presented.
description: Submitted for publication in the procceedings of the QFTEXT'05, Barcelona 2005
Chemical composition and inhibitory effects of water extract of Henna leaves on reactive oxygen species, DNA scission and proliferation of cancer cells
Creators: name: Kumar, Manish
name: Chandel, Madhu
name: Kaur, Paramjeet
name: Pandit, Kritika
name: Kaur, Varinder
name: Kaur, Sandeep
name: Kaur, Satwinderjeet
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: Lawsonia inermis L.
subject: antioxidant activity
subject: cytotoxic
subject: HPLC
subject: polyphenols
subject: 610

description: From the centuries, Lawsonia inermis L. (Henna) is utilized in traditional health care system as a medicinal and cosmetic agent. The present study was intended to assess antiradical, DNA protective and antiproliferative activity of water extract of Lawsonia inermis L. leaves (W-LI). Antioxidant activity was estimated using various in vitro assays such as DPPH, ABTS, superoxide anion radical scavenging, FRAP, deoxyribose degradation and DNA protection assay. Growth inhibitory effects of W-LI were assessed using MTT assay against different cancer cell lines viz. HeLa, MCF-7, A549, C6 and COLO-205. From the results of antioxidant assays, it was found that W-LI quenched DPPH and ABTS cation radicals with IC50 value of 352.77 μg/ml and 380.87 μg/ml respectively. It demonstrated hydroxyl radical scavenging potential of 59.75 % at highest test dose of 1000 μg/ml in deoxyribose degradation assay. The results of FRAP assay showed that W-LI also possesses significant reducing activity. Extract inhibited hydroxyl radical induced pBR322 plasmid DNA strand scission, thus conferring DNA protection. Growth inhibition of various cancer cell lines was achieved to the varying extent on treatment with W-LI. Further, it was observed that activity was quite promising against colon cancer COLO-205 cells (GI50 121.03 μg/ml). HPLC profiling of W-LI revealed the presence of different polyphenolic compounds such as ellagic acid, catechin, quercetin, kaempferol etc. which might be contributing towards antioxidant and cytotoxic activity. The present study demonstrated that polyphenols rich W-LI extract from leaves of L. inermis possesses ability to inhibit oxidative radicals and cancer cells proliferation.
description: EXCLI Journal;Vol. 15, 2016
Quantized invariant tori in Andreev billiards of mixed phase space
Creators: name: Kaufmann, Z.
name: Kormányos, A.
name: Cserti, J.
name: Lambert, C. J.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Comparing the results of exact quantum calculations and those obtained from the EBK-like quantization scheme of Silvestrov et al [Phys. Rev. Lett. 90, 116801 (2003)] we show that the spectrum of Andreev billiards of mixed phase space can basically be decomposed into a regular and an irregular part, similarly to normal billiards. We provide the first numerical confirmation of the validity of this quantization scheme for individual eigenstates and discuss its accuracy.
description: 4 pages, 2 figures
RISK AND STRUCTURAL CHANGE IN AGRICULTURE: HOW INCOME SHOCKS INFLUENCE FARM SIZE
Creators: name: Roberts, Michael J.
name: Key, Nigel D.
name: Roberts, Michael J.
name: Key, Nigel D.
Publisher: name: Unknown
Year: 2002
Subjects: subject: Agricultural Finance
subject: Industrial Organization
subject: farm size
subject: farm structure
subject: income shocks
subject: liquidity constraint
subject: risk

description: Farm-level Census data and county-level income shock data reveal that past unexpected income shocks affect the rate of change in average farm size. Average farm size increases more quickly in counties experiencing negative income shocks as compared to counties experiencing positive income shocks. This result cannot be explained by perfect-market models, which predict farm size should adjust according to changes in the relative prices of labor and capital. We posit a model wherein cash flows affect liquidity, which in turn affects farm borrowing and capital costs. In the model, farms that do not face liquidity constraints benefit from negative income shocks because they reduce land values, so these farms expand while liquidity-constrained farms contract. Observed farm consolidation patterns and farm exit rates are consistent with a model wherein liquidity constraints affect small farms more than large farms.
Νομικά ζητήματα ηλεκτρονικών υπογραφών
Creators: name: Μαυρέλος, Ιωάννης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Ηλεκτρονικές υπογραφές
subject: Συμβάσεις
subject: Αστικό δίκαιο
subject: Ηλεκτρονικές συναλλαγές
subject: Νομολογία
subject: Διαδίκτυο
subject: Ασφάλεια

description: Στην παρούσα διπλωματική εργασία προσεγγίζεται το θέμα των νομικών ζητημάτων που άπτονται των ηλεκτρονικών υπογραφών. Προκειμένου να γίνει αντιληπτή η σημασία τους στο ψηφιακό χώρο (και δη στις ιδιωτικές συναλλαγές) θα αναλυθεί η φύση και η λειτουργία τους υπό το πρίσμα των διατάξεων του νέου Κανονισμού (Ε.Ε.) αρ. 910/2014, αλλά και η στάση της ελληνικής νομολογίας απέναντι στα νομικά ζητήματα που ανακύπτουν.
OPTION WEALTH AND BEQUEST VALUES: THE VALUE OF PROTECTING FUTURE GENERATIONS FROM THE HEALTH RISKS OF NUCLEAR WASTE STORAGE
Creators: name: Riddel, Mary C.
name: Shaw, W. Douglass
name: Riddel, Mary C.
name: Shaw, W. Douglass
Publisher: name: Unknown
Year: 2002
Subjects: Resource /Energy Economics and Policy

description: We devise a simple model of intergenerational altruism under uncertainty. We present an estimable form of the model that relies on a few, plausible, assumptions. We apply the model to data collected in a survey of Southern Nevadans concerning the proposed Yucca Mountain Nuclear Waste Repository in Nye County, NV. We find strong evidence of a bequest motive. Approximately one third of the option wealth lost by households near the repository can be attributed to costs to future generations.
Direct magnetic field detection in the innermost regions of an accretion disc
Creators: name: Donati, Jean-Francois
name: Paletou, Frederic
name: Bouvier, Jerome
name: Ferreira, Jonathan
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Models predict that magnetic fields play a crucial role in the physics of astrophysical accretion disks and their associated winds and jets. For example, the rotation of the disk twists around the rotation axis the initially vertical magnetic field, which responds by slowing down the plasma in the disk and by causing it to fall towards the central star. The magnetic energy flux produced in this process points away from the disk, pushing the surface plasma outwards, leading to a wind from the disk and sometimes a collimated jet. But these predictions have hitherto not been supported by observations. Here we report the direct detection of the magnetic field in the core of the protostellar accretion disk FU Orionis. The surface field reaches strengths of about 1 kG close to the centre of the disk, and it includes a significant azimuthal component, in good agreement with recent models. But we find that the field is very filamentary and slows down the disk plasma much more than models predict, which may explain why FU Ori fails to collimate its wind into a jet.
description: 11 pages, 3 figures
ESTIMATING DETERMINANTS OF STUDENT EVALUATION SCORES TO IMPROVE TEACHING
Creators: name: McCann, Laura M.J.
name: Burton, Michael P.
name: McCann, Laura M.J.
name: Burton, Michael P.
Publisher: name: Unknown
Year: 2001
Subjects: Teaching/Communication/Extension/Profession

description: Student evaluations are used for both formative and summative assessment of teachers. This paper provides a method to make more effective use of these student evaluations by individual teachers. Data on three years of evaluations in two courses were used to develop regression models to explain overall effectiveness of teaching. The relative importance of explanatory variables changed with the course taught.
TRADE ALLOCATION MODELING: COMPARING THE RESULTS FROM ARMINGTON AND LOCALLY REGULAR AI DEMAND SYSTEM SPECIFICATIONS OF A UK BEEF IMPORT DEMAND ALLOCATION MODEL
Creators: name: Hanrahan, Kevin F.
name: Westhoff, Patrick C.
name: Young, Robert E.
name: Hanrahan, Kevin F.
name: Westhoff, Patrick C.
name: Young, Robert E.
Publisher: name: Unknown
Year: 2001
Subjects: Demand and Price Analysis

description: Locally regular almost ideal demand system and Armington specifications of a UK beef import demand allocation model are estimated. A Bayesian methodology is used that allows for the incorporation of prior information from microeconomic theory. The results illustrate the potential of regularity constrained locally flexible functional forms in modeling trade.
Curtoceras meyeri Aubrechtová & Korn, 2025, sp. nov.
Creators: name: Aubrechtová, Martina
name: Korn, Dieter
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Cephalopoda
Tarphyceratida
Trocholitidae
Curtoceras
Curtoceras meyeri

description: Curtoceras meyeri sp. nov.
urn:lsid:zoobank.org:act: 69962EDA-B814-4DA9-84FA-8592B6E57609
Fig. 36; Table 24
Diagnosis
Species of the genus Curtoceras with an adult conch exceeding 40 mm in diameter. At 40 mm diameter, the conch is discoidal (CWI ~ 0.45) and subevolute (UWI ~ 0.45) with high coiling rate (WER ~ 2.20); whorl profile with rounded flanks and venter, weakly depressed (WWI ~ 1.35) and weakly embracing (IZR = 0.05). Shell surface with lirae. Phragmocone chambers short (RCL ~ 0.10). Suture line almost straight or with a very shallow lateral lobe and a ventral saddle. Siphuncle subdorsal (RSP ~ 0.85) and narrow (RSH ~ 0.15).
Etymology
Named after Günter Meyer (Bernau), who donated a well-preserved Curtoceras specimen to be studied herein.
Type material
Holotype
GERMANY • unspecified locality in northern Germany;?Lasnamägi Regional Stage; illustrated in Fig. 36A; MB.C. 11550.
Description
Holotype MB.C.11550 (Fig. 36A) is a subadult conch with 41 mm diameter and has almost three whorls preserved; the body chamber is missing. In the last half whorl, the conch is discoidal (CWI = 0.46) and subevolute (UWI = 0.44); the coiling rate is high (WER = 2.20). The whorl profile has broadly rounded flanks and venter; it is weakly depressed (WWI = 1.35) and weakly embracing (IZR = 0.04) (Fig. 36B). The shell ornament is preserved only in a small area on the venter, where it consists of lirae that extend into a ventral sinus. The phragmocone chambers are short (RCL = 0.11). The suture line is almost straight or possesses a very shallow lateral lobe; however, on the venter of at least the last whorl, the suture line extends into a progressively pronounced saddle. The siphuncle is subdorsal in position (RSP = 0.85) and about 0.16 in relative diameter (RSH).
Remarks
Curtoceras meyeri sp. nov. differs from other species of Curtoceras in the increasingly pronounced external saddle of the suture line starting with the third whorl, combined with the comparably high WWI and comparatively short phragmocone chambers.
description: Published as part of Aubrechtová, Martina & Korn, Dieter, 2025, The coiled Middle Ordovician cephalopod genera Trocholites and Curtoceras (Tarphyceratida) from Baltoscandia and north-central Europe, pp. 1-78 in European Journal of Taxonomy 982 on pages 69-70, DOI: 10.5852/ejt.2025.982.2843, http://zenodo.org/record/15096341
Η αναμόρφωση του δικαίου των ανωνύμων εταιρειών - Ν. 4548/2018
Creators: name: Παπαλυμπέρη, Βασιλεία
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2019
Subjects: subject: Νέος νόμος ανωνύμων εταιρειών
subject: Ανώνυμες εταιρείες
subject: Ν.4548/2018
subject: Εταιρικό δίκαιο
subject: Αναμόρφωση του δικαίου των ανωνύμων εταιριών

description: Στις 13 Ιουνίου του 2018, δημοσιεύθηκε στην Εφημερίδα της Κυβερνήσεως ο Νόμος 4548/2018 (ΦΕΚ Α’ 104/13.6.2018) για την αναμόρφωση του δικαίου των ανωνύμων εταιρειών. Ο νόμος 4548/2018 αποτελεί προϊόν προσπάθειας που ξεκίνησε το 2013, κατέληξε σε προσωρινό σχέδιο αρχές του 2015, ξεκίνησε εκ νέου Φεβρουαρίου 2018 και ολοκληρώθηκε το Μάιο 2018. Η έκδοση ενός νόμου που διέπει τις ΑΕ, εντάσσεται σε μια ευρύτερη προσπάθεια της τελευταίας οκταετίας για ανανέωση του εταιρικού δικαίου στην Ελλάδα, μια προσπάθεια που αφορά όχι μόνο τις κεφαλαιουχικές εταιρίες (εισαγωγή της ΙΚΕ με το ν. 4072/2012, αναμόρφωση του δικαίου της ΕΠΕ με το ν. 4541/2018), αλλά και τις προσωπικές (ν. 4072/2012). Είναι σημαντικό ότι η ανανέωση του εταιρικού δικαίου συμβαδίζει με ανάλογες προσπάθειες σε κοντινούς τομείς, όπως είναι η εταιρική δημοσιότητα, η διευκόλυνση σύστασης των εταιρειών, οι εταιρικοί μετασχηματισμοί, το λογιστικό δίκαιο των επιχειρήσεων και το πτωχευτικό δίκαιο. Επίσης, σημαντικό είναι ότι όλη αυτή η προσπάθεια δεν βασίζεται μόνο στις επιταγές της Ευρωπαϊκής Ένωσης και των «Μνημονίων», αλλά αποτελεί γνήσια ελληνική προσπάθεια, που στηρίζεται στην ελπίδα ότι ανταποκρίνεται έτσι καλύτερα στις ελληνικές ανάγκες και ιδιαιτερότητες. Η επιλογή του νομοθέτη για σύνταξη ενός νέου νόμου αντί της τροποποίησης του προϋφιστάμενου, σχεδόν 100 χρόνια μετά τον ΚΝ 2190/1920, υποκινήθηκε κυρίως από την ευρεία έκταση των αλλαγών που επήλθαν αλλά και από την αναγκαιότητα ρύθμισης μικρότερης εμβέλειας ζητημάτων, τα οποία όμως έχουν σημαντική επίδραση στον τρόπο λειτουργίας των εμπορικών εταιρειών. Ο Έλληνας νομοθέτης, αφουγκραζόμενος την ανάγκη προσαρμογής και εναρμόνισης της ελληνικής νομοθεσίας με τα ευρωπαϊκά πρότυπα για τη λειτουργία των ανωνύμων εταιρειών, προχώρησε σε συνολική αναδιαμόρφωση της βασικής νοµοθεσίας για τις Ανώνυμες Εταιρείες. Η ισχύς του νέου νόμου άρχισε την 1.1.2019, ώστε να υπάρξει ικανό χρονικό περιθώριο για την ενημέρωση των ενδιαφερομένων και των νομικών τους παραστατών. Μέχρι τότε ίσχυσε κανονικά ο ΚΝ 2190/1920, που όμως συνεχίζει να εφαρμόζεται, στο μέτρο που αυτό ορίζεται στις μεταβατικές διατάξεις του άρθρου 187. Οι διατάξεις για τη μετατροπή, τη συγχώνευση και τη διάσπαση των ΑΕ καταργήθηκαν και αυτές με το νεότερο νόμο 4601/2019 για τους εταιρικούς μετασχηματισμούς. Ο νέος νόμος αποτελείται από 14 «τμήματα» και 189 άρθρα. Στην παρούσα εργασία θα αναλυθούν οι νέες ρυθμίσεις, οι οποίες αποβλέπουν σε μια καλύτερη και αποτελεσματικότερη λειτουργία της ανώνυμης εταιρείας, αξιοποιούν την τεχνολογία, βελτιώνουν τη θέση των μετόχων, απλοποιούν την εταιρική καθημερινότητα, με αντίστοιχη εξοικονόμηση κόστους και εισάγουν καινοτομίες, που κρίθηκαν ότι μπορεί να προάγουν την λειτουργία του επιχειρηματικού κόσμου.
PREDICTING ORGANIC MARKET DEVELOPMENT WITH SPATIAL ANALYSIS OF EXISTING INDUSTRY INFORMATION
Creators: name: Lohr, Luanne
name: Gonzalez-Alvarez, Yassert
name: Graf, Anita
name: Lohr, Luanne
name: Gonzalez-Alvarez, Yassert
name: Graf, Anita
Publisher: name: Unknown
Year: 2001
Subjects: subject: Marketing
subject: FOS: Economics and business

description: We test the likelihood of expansion for six market sectors based on the similarities between counties with and counties without organic markets. Results indicate that sales projections are overstated. Growth imbalance will continue to favor the West and North Central regions over the South and Northeast.
Integrated Microfluidic Pumps - by Blue Light Actuation of Liquid Crystal Network Films
Creators: name: Schmidleithner, Christina
name: Peham, Johannes R.
Publisher: name: Zenodo
Year: 2023
Subjects: Microfluidics
Micropump
Liquid Crystal Network
Photoactuator

description: As lab-on-a-chip devices aim to incorporate complex and multi-step microfluidic workflows, active fluid control within these platforms is gaining significance. To that end, we aim to develop a photoactive micropump for integration into disposable microfluidic cartridges. As actuating mechanism, we select splay oriented liquid crystal networks (LCN) stimulated with 455 nm blue LED light. Upon illumination, the LCN film bends and it reverts back to its original state in the dark. In a pumping setup, this action deflects the membrane of a pumping chamber and two passive check-valves ensure directional fluid flow. Thus, fluid volumes can be manipulated in a non-contact actuation setup, potentially enabling automated workflows from sample preparation to analysis
Does Decentralized Welfare Reform Lead to a Race to the Bottom in Local Economic Development and Local Public Services?
Creators: name: Baryeh, Afia
name: Kraybill, David S.
name: Baryeh, Afia
name: Kraybill, David S.
Publisher: name: Unknown
Year: 2001
Subjects: Community/Rural/Urban Development

description: This paper tests the hypothesis that devolution of welfare programs leads to heightened intergovernmental competition and a "race to the bottom" in the provision of local public services. Data from a national survey of county governments is used to estimate an econometric model of strategic interaction by county governments.
Isolation and cultivation of adult primary bovine hepatocytes from abattoir derived liver
Creators: name: Ehrhardt, Sonja
name: Schmicke, Marion
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: hepatocyte
subject: liver
subject: cell culture
subject: cattle
subject: sandwich
subject: 610

description: The aim was to establish a cell culture of adult primary bovine hepatocytes obtained from liver following slaughter and to cultivate the cells in a sandwich culture. Cells and medium samples were taken after separation of cells (day 0), during monolayer (days 1, 2 and 3) and during sandwich culture (days 1, 2, 3, 4, 7, 10 and 14). The mRNA expression of BAX, BCL2L, FAS, IGF-1 and GHR1A was measured as well as urea and LDH. Hepatocytes were obtained by using a two-step collagenase perfusion and were purified thereafter by density gradient centrifugation. The viability was 68.2 ± 9.5 %. In sandwich culture, cells have a typical polygonal hepatocytelike shape, build cell-cell contacts, and show irregularity of cell borders suggesting bile canaliculi generation. The BAX mRNA expression increased on day 1 as well but decreased steadily until day 3 and remained constant for 14 days. Urea- and LDH-concentrations increased from day 4 to day 7. In conclusion, we found that it is possible to gather viable primary hepatocytes from adult bovine liver after slaughter, and that cells gathered this way show typical morphologies, urea-production and low LDH-leakage especially at day 4 in a sandwich system.
description: EXCLI Journal;Vol. 15, 2016
Exploring Open Access E-Resources through Subject Gateways: A Special Reference to ELT Gateway
Creators: name: T, Manjula
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 461099
subject: Library and information studies not elsewhere classified
classificationCode: 461007
subject: Open access

description: Information seekers search for information online and lead themselves to an erroneous situation due to the vast information resources available online, both authentic and inauthentic. They have difficulties in finding relevant information. They may be unaware of different websites and resources available online on the specific subject. The Subject Gateway must be created to make them acquainted with all the open-access resources available online in the specific subject field. Subject gateways link all the open-access e- resources available online, like e-reference sources, e-books, e-journals, reports, audio and video resources, databases, course wares, and other resources. This article provides information about the basic structure and usage of a subject gateway, especially focusing on the ‘English Language Teaching (ELT) Subject Gateway’ created on the Webnode platform. The ELT gateway contains links to different open-access e-resources available on ELT. This article gives a brief explanation of how to use the ELT Subject Gateway’s E- Reference Sources, E-books, E-Journals, Mobile Apps, Audio-Video Materials, YouTube Channels, E-Textbooks, and online resources on ELT.
Yet another lesson on the stability conditions in multi-Higgs potentials
Creators: name: Ivanov, Igor P.
name: Vazão, Francisco
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We discuss a rather common but often unnoticed pitfall which arises when deriving the bounded-from-below (BFB) conditions in multi-Higgs models with softly broken global symmetries. Namely, necessary and sufficient BFB conditions derived for the case with an exact symmetry can be ruined by introducing soft symmetry breaking terms. Using $S_4$ and $A_4$-symmetric three-Higgs-doublet models as an example, we argue that all published necessary and sufficient BFB conditions, even those which are correct for the exactly symmetric case, are no longer sufficient if soft symmetry breaking is added. Using the geometric formalism, we derive the exact necessary and sufficient BFB conditions for the 3HDM with the symmetry group $S_4$, either exact or softly broken, and review the situation for the $A_4$-symmetric case.
description: 26 pages, 4 figures
ECONOMIC ANALYSIS OF THE CHANGING STRUCTURE OF THE U.S. FERTILIZER INDUSTRY
Creators: name: Kim, C.S.
name: Taylor, Harold
name: Hallahan, Charles B.
name: Schaible, Glenn D.
name: Kim, C.S.
name: Taylor, Harold
name: Hallahan, Charles B.
name: Schaible, Glenn D.
Publisher: name: Unknown
Year: 2001
Subjects: Agribusiness

description: This article evaluates structural changes in the U.S. nitrogen fertilizer industry by using a decomposed Negative Binomial Regression model. Results indicate that the U.S. nitrogen fertilizer industry can be characterized as an industry involving price leadership in oligopoly. Declining profit-margins might have forced fertilizer producers to consolidate and eliminate duplicate operations. The market concentration level is expected to intensify as the natural gas price rises.
AN ECONOMETRIC ANALYSIS OF OFF-FARM LABOR PARTICIPATION AMONG U.S. FARM FAMILIES, 1977-1998.
Creators: name: Oluwole, Adetokunbo B.
name: Findeis, Jill L.
name: Oluwole, Adetokunbo B.
name: Findeis, Jill L.
Publisher: name: Unknown
Year: 2001
Subjects: Labor and Human Capital

description: Analyses of a sample of U.S. farm families based on March Current Population data for 1977-98 show that off-farm work decisions are made jointly by farm couples. Demographic differences across households are shown to have very important effects, while traditional farm policies appear less likely to influence off-farm work decisions.
Integrated Microfluidic Pumps - by Blue Light Actuation of Liquid Crystal Network Films
Creators: name: Schmidleithner, Christina
name: Peham, Johannes R.
Publisher: name: Zenodo
Year: 2023
Subjects: Microfluidics
Micropump
Liquid Crystal Network
Photoactuator

description: As lab-on-a-chip devices aim to incorporate complex and multi-step microfluidic workflows, active fluid control within these platforms is gaining significance. To that end, we aim to develop a photoactive micropump for integration into disposable microfluidic cartridges. As actuating mechanism, we select splay oriented liquid crystal networks (LCN) stimulated with 455 nm blue LED light. Upon illumination, the LCN film bends and it reverts back to its original state in the dark. In a pumping setup, this action deflects the membrane of a pumping chamber and two passive check-valves ensure directional fluid flow. Thus, fluid volumes can be manipulated in a non-contact actuation setup, potentially enabling automated workflows from sample preparation to analysis
description: {"references": ["C. L. van Oosten, C. W. M. Bastiaansen, and D. J. Broer, \"Printed artificial cilia from liquid-crystal network actuators modularly driven by light,\" Nature materials, vol. 8, no. 8, pp. 677\u2013682, 2009"]}
MAKTABGACHA TA'LIM TASHKILOTI RAXBARLARINING KASBIY KOMPETENSIYASINI RIVOJLANTIRISH MEXANIZMLARINI TAKOMILLASHTIRISH
Creators: name: Kurbanov, Ibratbek
Publisher: name: Zenodo
Year: 2024

description: Maktabgacha ta’lim tashkilotlari va boshqa ta’lim tashkilotlarining ish faoliyatini samarali qilish, rivojlantirishning asosiy vazifasi raxbar hodimlarga bog’liq. Bugungi kunda tashkilot raxbarlariga qo’yilayotgan talablar juda ma’sulyatli va birmuncha chuqur tafakkurni talab etadi. Ushbu maqolada maktabgacha ta’lim tashkiloti raxbarlarining kasbiy kompetensiyasini rivojlantirish mexanizmlarini takomillashtirish bo’yicha ilmiy munozaralar yuritilgan.
Thermal evolution and activity of Comet 9P/Tempel 1 and simulation of a deep impact
Creators: name: Sarid, G.
name: Prialnik, D.
name: Meech, K. J.
name: Pittichova, J.
name: Farnham, T. L.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We use a quasi 3-D thermal evolution model for a spherical comet nucleus, which takes into account the diurnal and latitudinal variation of the solar flux, but neglects lateral heat conduction. We model the thermal evolution and activity of Comet 9P/Tempel 1, in anticipation of the Deep Impact mission encounter with the comet. We also investigate the possible outcome of a projectile impact, assuming that all the energy is absorbed as thermal energy. An interesting result of this investigation, is that the estimated amount of dust ejected due to the impact is equivalent to 2--2.6 days of activity, during "quiet" conditions, at perihelion. We show that production rates of volatiles that are released in the interior of the nucleus depend strongly on the porous structure, in particular on the surface to volume ratio of the pores. We develop a more accurate model for calculating this parameter, based on a distribution of pore sizes, rather than a single, average pore size.
description: 25 pages, 8 figures, accepted for publication in PASP (in press). For fig.xx (composite image, sec.4) and a better resolution of fig.6 see, http://geophysics.tau.ac.il/personal/gal%5Fsarid/
Comparison of melatonin with growth factors in promoting precursor cells proliferation in adult mouse subventricular zone
Creators: name: Sotthibundhu, Areechun
name: Ekthuwapranee, Kasima
name: Govitrapong, Piyarat
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: epidermal growth factor
subject: extracellular signal-regulated protein kinase
subject: melatonin
subject: mitogen-activated protein kinase
subject: neural stem cells
subject: subventricular zone
subject: 610

description: Melatonin, secreted mainly by the pineal gland, plays roles in various physiological functions including protecting cell death. We showed in previous study that the proliferation and differentiation of precursor cells from the adult mouse subventricular zone (SVZ) can be modulated by melatonin via the MT1 melatonin receptor. Since melatonin and epidermal growth factor receptor (EGFR) share some signaling pathway components, we investigated whether melatonin can promote the proliferation of precursor cells from the adult mouse SVZ via the extracellular signal-regulated protein kinase /mitogen-activated protein kinase (ERK/MAPK) pathways in comparison with epidermal growth factor (EGF). Melatonin-induced ERK/MAPK pathways compared with EGF were measured by using in vitro and vivo models. We used neurosphere proliferation assay, immunocytochemistry, and immuno-blotting to analyze significant differences between melatonin and growth factor treatment. We also used specific antagonist and inhibitors to confirm the exactly signaling pathway including luzindole and U0126. We found that significant increase in proliferation was observed when two growth factors (EGF+bFGF) and melatonin were used simultaneously compared with EGF + bFGF or compared with melatonin alone. In addition,the present result suggested the synergistic effect occurred of melatonin and growth factors on the activating. the ERK/MAPK pathway. This study exhibited that melatonin could act as a trophic factor, increasing proliferation in precursor cells mediated through the melatonin receptor coupled to ERK/MAPK signaling pathways. Understanding the mechanism by which melatonin regulates precursor cells may conduct to the development of novel strategies for neurodegenerative disease therapy.
description: EXCLI Journal;Vol. 15, 2016
DAIRY FARM MANAGEMENT AND LONG-TERM FARM FINANCIAL PERFORMANCE: EVIDENCE FROM PANEL DATA
Creators: name: Gloy, Brent A.
name: Hyde, Jeffrey
name: LaDue, Eddy L.
name: Gloy, Brent A.
name: Hyde, Jeffrey
name: LaDue, Eddy L.
Publisher: name: Unknown
Year: 2001
Subjects: Agricultural Finance
Livestock Production/Industries

description: The financial performance and relationships between several management factors and farm financial performance are examined in a panel data set of 107 New York dairy farms. The overall level of compound and annual return on assets of the farms considered in this study was quite low. However, the evidence clearly suggests that the most profitable and least profitable farms are consistently so. Correlations of the yearly rankings of farm profitability were always positive and significantly different from zero. Two regression models were estimated in an effort to identify management factors that influence profitability. In general, the models explain a relatively high degree of the variation in both compound return on assets and annual return on assets. These models tend to indicate that farm size, changes in farm size, and production management factors, such as milk production per cow, were positively related to farm profitability. While farm size was positively related to both compound return on assets and annual return on assets, the practice of undertaking expansions that were large relative to farm size was negatively related to compound return on assets.
AN ECONOMIC ANALYSIS OF THE DAIRY ENVIRONMENTAL COOPERATIVE IN NORTHEAST KANSAS
Creators: name: Vogt, Michael L.
name: Kastens, Terry L.
name: Vogt, Michael L.
name: Kastens, Terry L.
Publisher: name: Unknown
Year: 2001
Subjects: subject: Environmental Economics and Policy
subject: Dairy Environmental Cooperative (DEC)
subject: manure management
subject: Net Present Value (NPV) analysis
subject: cost-share
subject: concrete manure storage

description: In 1997, the Black Vermillion Dairy Environmental Cooperative (DEC) was started with an EPA 319A grant. Ten Kansas dairies located in the Kansas Black Vermillion Watershed were studied to evaluate the on-farm manure structures cost-shared by the DEC. Net present value (NPV) analysis was used to evaluate the profitability associated with the manure structures. The NPV analysis showed that in most cases, investing in a manure storage structure is a worthwhile venture and can be profitable for the dairy. However, cost-share assistance often will be needed in order to have positive pre-tax and after-tax NPVs.
Red Mergers and the Assembly of Massive Elliptical Galaxies: the Fundamental Plane and its Projections
Creators: name: Boylan-Kolchin, Michael
name: Ma, Chung-Pei
name: Quataert, Eliot
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Several recent observations suggest that gas-poor (dissipationless) mergers of elliptical galaxies contribute significantly to the build-up of the massive end of the red sequence. We perform a series of major merger simulations to investigate the spatial and velocity structure of the remnants of such mergers. Regardless of orbital energy or angular momentum, we find that the stellar remnants lie on the fundamental plane defined by their progenitors, a result of virial equilibrium with a small tilt due to an increasing central dark matter fraction. However, the locations of merger remnants in the projections of the fundamental plane -- the Faber-Jackson and R_e-M_* relations -- depend strongly on the merger orbit, and the relations steepen significantly from the canonical scalings (L sigma^4 and R_e M_*^0.6) for mergers on radial orbits. Our results imply that the projections of the fundamental plane -- but not necessarily the plane itself -- provide a powerful way of investigating the assembly history of massive elliptical galaxies, including the brightest cluster galaxies at or near the centers of galaxy clusters. We argue that most massive ellipticals are formed by anisotropic merging and that their fundamental plane projections should thus differ noticeably from those of lower mass ellipticals even though they should lie on the same fundamental plane. Current observations are consistent with this conclusion. The steepening in the L-sigma relation for luminous ellipticals may also be reflected in a corresponding steepening in the M_BH-sigma relation for massive black holes.
description: 10 pages, 4 figures. Accepted for publication in MNRAS
Bromelain capped gold nanoparticles as the novel drug delivery carriers to aggrandize effect of the antibiotic levofloxacin
Creators: name: Bagga, Paramdeep
name: Ansari, Tarique Mahmood
name: Siddiqui, Hefazat Hussain
name: Syed, Asad
name: Bahkali, Ali H.
name: Rahman, Md. Azizur
name: Khan, Mohd. Sajid
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: antibacterial activity
subject: bromelain
subject: gold nanopart icles
subject: levofloxacin
subject: novel drug delivery carriers
subject: 610

description: To develop bromelain capped gold nanoparticles (BRN capped Au-NPs) as the effective drug delivery carriers of the antibiotic levofloxacin (LvN) and evaluate antibacterial potential of its bioconjugated form compared to pure LvN. BRN capped Au-NPs were synthesized by in vitro method and bioconjugated to LvN using 1-ethyl-3-(3-dimethylamino-propyl)-carbodiimide as activator to form Au-BRN-LvN-NPs. These were characterized for mean particle size by dynamic light scattering analysis, zeta potential by Zetasizer nanosystem analysis and transmission electron microscopy (TEM) on carbon coated TEM copper grids by TEM respectively. Drug loading efficiency of LvN was calculated using UV-visible spectroscopy by standard curve of pure LvN. Antibacterial efficacy of Au-BRN-LvN-NPs and pure LvN was determined by evaluating minimum inhibitory concentration (MIC) against Staphylococcus aureus and Eschereschia coli.Two peaks were observed in Au-BRN-LvNNPs spectrum one at 307 nm and other at 526 nm while one peak in BRN capped Au-NPs at 522 nm during UV spectroscopy suggesting red shift. The drug loading efficiency of LvN was found to be 84.8 ± 2.41 %. The diameter of Au-BRN-LvN-NPs and BRN capped Au-NPs were found to be (58.65 ± 2 nm, 38.11 ± 2 nm), zeta potential (-9.01 mV, -13.8 mV) and surface morphology (~13.2 nm, 11.4 nm) respectively. The MICs against S. aureus and E. coli were found to be (0.128 μg/mL, 1.10 μg/mL) for Au-BRN-LvN-NPs and (0.547 μg/mL, 1.96μg/mL) for pure LvN. The results suggested that BRN capped Au-NPs can be used as effective drug delivery carriers of the antibiotic LvN. The Au-BRN-LvN-NPs exhibited enhanced antibacterial activity compared to pure LvN alone.
description: EXCLI Journal;Vol. 15, 2016
Elasticities and stabilities: lipid membranes vs cell membranes
Creators: name: Tu, Z. C.
name: An, R.
name: Ou-Yang, Z. C.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Other Quantitative Biology (q-bio.OT)
subject: Cell Behavior (q-bio.CB)
subject: FOS: Biological sciences

description: A cell membrane can be simply regarded as composite material consisting of lipid bilayer, membrane cytoskeleton beneath lipid bilayer, and proteins embedded in lipid bilayer and linked with membrane cytoskeleton if one only concerns its mechanical properties. In this Chapter, above all, the authors give a brief introduction to some important work on mechanical properties of lipid bilayers following Helfrich's seminal work on spontaneous curvature energy of lipid bilayers. Next, the entropy of a polymer confined in a curved surface and the free energy of membrane cytoskeleton are obtained by scaling analysis. It is found that the free energy of cell membranes has the form of the in-plane strain energy plus Helfrich's curvature energy. The equations to describe equilibrium shapes and in-plane strains of cell membranes by osmotic pressures are obtained by taking the first order variation of the total free energy containing the elastic free energy, the surface tension energy and the term induced by osmotic pressure. The stability of spherical cell membrane is discussed and the critical pressure is found to be much larger than that of spherical lipid bilayer without membrane cytoskeleton. Lastly, the authors try to extend the present static mechanical model of cell membranes to the cell structure dynamics by proposing a group of coupling equations involving tensegrity architecture of cytoskeleton, fluid dynamics of cytoplasm and elasticities of cell membranes.
description: 14 pages. Accepted as a chapter in Soft-condensed matter: new researches (Nova, 2005)
title: Lupane-type triterpenes and their anti-cancer activities against most common malignant tumors
title: a review
titleType: AlternativeTitle
Creators: name: Cháirez-Ramírez, M. H.
name: Moreno-Jiménez, M. R.
name: González-Laredo, R. F.
name: Gallegos-Infante, J. A.
name: Rocha-Guzmán, N. E.
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: lupeol
subject: betulin
subject: betulinic acid
subject: cancer
subject: signaling pathway
subject: 610

description: In recent times, a great deal of interest has been motivated on plant derived compounds known as nutraceuticals. These compounds exert important beneficial activities that improve people’s health status when are consumed regularly, and now they appear as a viable option to explore their possible therapeutic effects against diseases like cancer. Particularly, lupane-type triterpenes have shown great ability to modulate multiple cancer-related signaling pathways and processes, including NF-κB, Wnt/β-catenin, PI3K/Akt, apoptosis, and many other routes related to proliferation or cell death, which are uncontrolled in malignant tumors. These investigations have promoted in vitro and in vivo studies, searching their mechanisms of action; although more research is still needed to prove its potential in human clinical trials. This review focuses on the ability of betulin, betulinic acid and lupeol to show benefits against the most common types of malignant tumors, which are considered a major global threat for public health.
description: EXCLI Journal;Vol. 15, 2016
Study of freeze-out dynamics of strange hadrons
Creators: name: Singh, Sushant K.
name: Ghosh, Purabi
name: Nayak, Jajati K.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We study the chemical freeze-out dynamics of strange particles ($K,\, Λ,\, Σ$) from a homogeneous and isotropically expanding hadronic system of $π, K, ρ, N, Λ$ and $Σ$ with zero net baryon density. We use the momentum integrated Boltzmann equation and study their evolution over the bulk hadronic matter, a condition being similar to the one created at top RHIC and LHC energies. The cross-sections, which are input to the equations, are taken either from phenomenological models or parameterized by comparing against experimental data. From this microscopic calculation we find that these strange particles freeze-out near transition temperature $\approx T_c$ due to large relaxation time. The continuous cease of the inelastic processes due to gradual fall in the temperature and decrease in the number density, thus lead to early freeze out of strange hadrons $K, Λ$ and $Σ$ which happens sequentially near $T_c$. However, freeze-out of these strange species near Tc appears as a sudden and simultaneous process, which is mostly predicted by thermal model while explaining the yield of identified particles at RHIC and LHC energies.
The past and present of serum aminotransferases and the future of liver injury biomarkers
Creators: name: McGill, Mitchell R.
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: liver injury
subject: liver disease
subject: diagnostics
subject: biomarkers
subject: mechanistic biomarkers
subject: 610

description: Laboratory testing is important in the diagnosis and monitoring of liver injury and disease. Current liver tests include plasma markers of injury (e.g. aminotransferases, γ-glutamyl transferase, and alkaline phosphatase), markers of function (e.g. prothrombin time, bilirubin), viral hepatitis serologies, and markers of proliferation (e.g. α- fetoprotein). Among the injury markers, the alanine and aspartate aminotransferases (ALT and AST, respectively) are the most commonly used. However, interpretation of ALT and AST plasma levels can be complicated. Furthermore, both have poor prognostic utility in acute liver injury and liver failure. New biomarkers of liver injury are rapidly being developed, and the US Food and Drug Administration the European Medicines Agency have recently expressed support for use of some of these biomarkers in drug trials. The purpose of this paper is to review the history of liver biomarkers, to summarize mechanisms and interpretation of ALT and AST elevation in plasma in liver injury (particularly acute liver injury), and to discuss emerging liver injury biomarkers that may complement or even replace ALT and AST in the future.
description: EXCLI Journal;Vol. 15, 2016
On instability mechanisms for inverse problems
Creators: name: Koch, Herbert
name: Rüland, Angkana
name: Salo, Mikko
Publisher: name: arXiv
Year: 2020
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this article we present three robust instability mechanisms for linear and nonlinear inverse problems. All of these are based on strong compression properties (in the sense of singular value or entropy number bounds) which we deduce through either strong global smoothing, only weak global smoothing or microlocal smoothing for the corresponding forward operators, respectively. As applications we for instance present new instability arguments for unique continuation, for the backward heat equation and for linear and nonlinear Calderón type problems in general geometries, possibly in the presence of rough coefficients. Our instability mechanisms could also be of interest in the context of control theory, providing estimates on the cost of (approximate) controllability in rather general settings.
description: 93 pages, 1 figure, comments welcome, corrected some typos
Depression in long-term care patients : evaluation of a screening protocol and outcomes of drug therapy
Creators: name: Soon, Judith Alice
Publisher: name: University of British Columbia
Year: 2009

description: Depression is often underdiagnosed and undertreated in elderly long-term care patients. Recommendations have been made to increase the identification and treatment of depression in late life, despite the fact that efficacy and outcomes of antidepressant treatment have not been established in this population. The first component of this research was an 8-week randomized clinical trial to assess the effect of a screening protocol on physicians' identification and treatment of depression. The clinical screening study of 1602 patients in 22 long-term care facilities identified 103 untreated patients ≥ 65 years with adequate cognitive function and a Geriatric Depression Scale score ≥ 13. The 77 physicians of the 103 patients were randomized by cluster into an early (experimental, notified of screening results) or a delayed (control, notified 4 weeks later) group. The primary outcome was the effect of the screening protocol on physicians' decisions to prescribe antidepressant therapy or refer to mental health services. Physician response in the early group (25%) was greater than that in the delayed group (2%) (p < 0.005) by 4 weeks from baseline. The combined physician response rate was 36% (95% CI, 26% to 46%) at 8 weeks from notification, and overall physician action occurred in 69% (95% CI, 60% to 78%). Logistic regression suggested that physicians' decisions to treat or refer were not related to severity of symptoms of depression or other patient characteristics, but were primarily associated with physician-related characteristics. The second component of the research was a 26-week prospective, observational outcomes study of depressed patients newly treated with antidepressants, and a similar group of untreated patients. Therapeutic outcomes of interest were mean within-group changes in symptoms of depression, cognitive function, self-perceived health status, and functional ability at 6, 12, and 26 weeks for treated patients, and at 26 weeks for untreated patients. While symptoms of depression improved in treated patients over the period of 26 weeks, other measures of quality of life and physical function did not improve. Similar observations were made in the untreated group. The results support the idea that randomized controlled effectiveness studies in long-term care patients are both ethical and necessary.
NGC 4435: a bulge dominated galaxy with an unforeseen low mass central black hole
Creators: name: Coccato, L.
name: Sarzi, M.
name: Pizzella, A.
name: Corsini, E. M.
name: Bonta', E. Dalla
name: Bertola, F.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the ionised gas kinematics of the SB0 galaxy NGC 4435 from spectra obtained with the Space Telescope Imaging Spectrograph. This galaxy has been selected on the basis of its ground-based spectroscopy, for displaying a position velocity diagram consistent with the presence of a circumnuclear Keplerian disc rotating around a supermassive black hole (SMBH). We obtained the Halpha and [NII](6583) kinematics kinematics in the galaxy nucleus along the major axis and two parallel offset positions. We built a dynamical model of the gaseous disc taking into account the whole bidimensional velocity field and the instrumental set-up. For the mass of the central SMBH we found an upper limit of 7.5e6 Msun at 3sigma level. This indicates that the mass of SMBH of NGC 4435 is lower than the one expected from the Mbh-sigma (5e7 Msun) and near-infrared Mbh- Lbulge (4e7 Msun) relationships.
description: Accepted for publication in MNRAS