cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
LC-UV and LC-MS/MS detection and quantification of steroid hormones in edible food samples and water using solid phase extraction
Creators: name: Areeg Z. Alkaraly
name: Kormod, Lubna
name: Abdelsalam, Randa A.
name: Hadad, Ghada M.
name: El-Gendy, Ahmed E.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: Animal products are a major source of human exposure to steroids, this resulted in a critical request for applicable methods for the determination of these steroid hormones in pure form and in different matrices such as hen eggs, chicken liver and water. The aim was to develop a reliable LC-UV and LC-MS/MS for the determination of selected steroid hormones in edible samples, using SFE and LLE for sample preparation. LC-MS/MS method was validated for separation and quantification of selected steroid hormones; Ethinyl oestradiol, testosterone, 17 alpha methyltestosterone, and progesterone, using mobile phase of methanol and 0.1% Formic in ratio (70:30) at different m/z ratios. The developed method has satisfactory linearity and the spiking recoveries of the steroid hormones were between 90.25% and 99.45% with RSDs lower than 5%. The results demonstrated that the developed approach has high sensitivity and repeatability and can be helpful in the determination of steroid residues in complex food matrices.
title: Cor triatriatum: the role of cardiac-MR in establishing a correct diagnosis
Creators: name: Minoiu, Costin
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Education and training
subject: Congenital
subject: Education
subject: Contrast agent-intravenous
subject: Computer Applications-Detection, diagnosis
subject: Ultrasound
subject: MR
subject: Cardiovascular system
subject: Cardiac

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To illustrate the cardiac-MR findings consistent with diagnosis of cor triatriatum To underscorecardiac-MR findingsimportance to avoid diagnostic pitfalls. To summarize the most recent literature on cor...
Initiatives to improve the use of opioids in the UK: a systematic review
Creators: name: Richards, Georgia
name: Peacock, Max
name: Heneghan, Carl
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences

description: ​​Opioids are a potent class of analgesics that are highly effective in the management of acute pain acting on the central and peripheral nervous system (1). There is however limited evidence of their efficacy in the treatment of chronic pain (2). Furthermore the long term use of opioids is associated with adverse effects in multiple organ systems, including long term respiratory depression causing hypoxemia and carbon dioxide retention, and death at high doses (3,4). Despite these risks, opioids are still prescribed for long term pain and at high doses, with 0.5 million people in England prescribed opioids for longer than three months in 2021 (5). In England,opioid prescribing increased by 127% between 1998 and 2016 (6). Opioid-related deaths were at an all-time high in 2020 with 2263 deaths (7). In response to these increases and to avoid an opioid crisis as seen in the US, a range of initiatives have been implemented to reduce opioid prescribing. In April 2021, NICE published guidelines (8) that advised against the use of opioids to treat chronic primary pain, and ΝΗS Improvement have set a target for reducing opioid prescribing by 50% by 2024 (5). To adhere to guidelines and meet such targets, prescribers across the UK will be embedding strategies to reduce use. However, this data is not being routinely collected or reviewed and resources may vary widely, which may put some patients at risk of adverse events. Ceasing opioid prescribing can also be harmful to patients leading to opioid withdrawal syndrome (9), but evidence on the harms of opioid reduction is limited. In 2017 a Cochrane Review was conducted to evaluate the effectiveness of interventions to reduce opioid prescribing, including non-pharmacological interventions such as cognitive behavioural therapy and electro-acupuncture (11). Another systematic review and meta-analysis assessed the efficacy of interventions to reduce opioid prescriptions in people with chronic non-cancer pain (12). The review found many intervention modalities that caused a reduction in opioid dose, categorised as pain self-management, alternative/complementary medicines, pharmacological and biomedical devices, opioid replacement treatment and deprescription methods. It is however still unclear how many of these interventions are occurring across the UK. This review aims to identify the prevalence and characteristics of initiatives for changing and monitoring opioid use, to understand geographical variation and patient outcomes.
Statistical Control Requires Causal Justification
Creators: name: Wysocki, Anna
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Causal Inference; Statistical Control

description: It is common practice in correlational or quasi-experimental studies to use statistical control to remove confounding effects from a regression coefficient. Controlling for relevant confounders can de-bias the estimated causal effect of a predictor on an outcome; that is, bring the estimated regression coefficient closer to the value of the true causal effect. But statistical control only works under ideal circumstances. When the selected control variables are inappropriate, controlling can result in estimates that are more biased than uncontrolled estimates. Despite the ubiquity of statistical control in published regression analyses and the consequences of controlling for inappropriate third variables, the selection of control variables is rarely explicitly justified in print. We argue that, to carefully select appropriate control variables, researchers must propose and defend a causal structure that includes the outcome, predictors, and plausible confounders. We underscore the importance of causality when selecting control variables by demonstrating how regression coefficients are affected by controlling for appropriate and inappropriate variables. Finally, we provide practical recommendations for applied researchers who wish to use statistical control.
Electroanalytical determination of Allura Red in beverage samples using an anodically pretreated graphite electrode
Creators: name: Uruc, Selen
name: Ozge Gorduk
name: Yucel Sahin
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: In this study, an anodically pretreated pencil graphite electrode (Ptre/PGE) which has oxygen-containing groups was used for the electrochemical determination of Allura Red (AR) by differential pulse voltammetry (DPV) method for the first time in the literature. In order to be more selective and sensitive the pencil graphite electrode, the anodic pretreatment process was performed by applying a constant +1.8 V potential for 250 s in pH 9 phosphate buffer solution using chronoamperometry method. The characterisation studies of the sensor were performed using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and atomic force microscopy (AFM) methods. Interference effects of sunset yellow, tartrazine, amaranth, aspartame, glucose, gelatin, and ascorbic acid on AR determination with Ptre/PGE were investigated. The limit of detection and quantitation values was found as 75 and 251 nmol L−1, respectively. The Ptre/PGE has been used for the determination of AR in cherry juice and energy drink samples, where it provides recovery ranging from 98.40% to 100.8%.
title: Multimodality Imaging Features of Portal Biliopathy
Creators: name: Oliveira, João
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Embolism / Thrombosis
subject: Cholangiography
subject: Ultrasound
subject: MR
subject: CT
subject: Liver
subject: Biliary Tract / Gallbladder
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To illustrate the imaging features of portal biliopathy in ultrasound (US), multidetector computer tomography (MDCT) and magnetic ressonance cholangiopancreatography (MRCP). To clarify the mechanisms involved in biliary abnormalities in patients...
title: What do we know about Heterotaxy Syndrome? - An illustrated guide.
Creators: name: Ageitos Casais, María Cruz
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Anatomy
subject: Cardiovascular system
subject: Abdomen
subject: CT
subject: Education
subject: eLearning
subject: Arteriovenous malformations
subject: Congenital

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: We describe the anatomic disorders that can be seen in the different imaging techniques in the Heterotaxy syndrome. This entity is part of the situs anomalies that can be present in humans, causing different visceral and vascular malpositions...
Design and development of advanced biosensing systems for the rapid detection of antibiotics
Creators: name: Sethu, Navya
name: Vyas, Renu
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy

description: The indiscriminate use of antibiotics has led to antimicrobial resistance (AMR) that is affecting both public and animal health, worldwide. To circumvent this and prevent antibiotics from entering the food chain, it is essential to detect them rapidly at the source. As most of the conventional methods used for the antibiotic detection in biological, food and environmental samples are time consuming and expensive, a suitable alternative is served by the biosensors which provide rapid, cost-effective and user-friendly platform for portable sensing applications. Development of devices using lab-on-a-chip technology has potential application in the field of development of biosensor-based antibiotic detection kits. This review gives a detailed discussion of various biosensors developed for antibiotic detection. Recent techniques such as the integration of biosensing and microfluidic technologies, along with the simulation softwares employed which aids in the miniaturisation of the biosensing devices are also highlighted in this review.
title: Typical skeletal location and differential diagnosis of bone tumors.
Creators: name: Barros, Marta
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Musculoskeletal bone
subject: Bones
subject: Oncology
subject: Conventional radiography
subject: CT
subject: MR
subject: Education
subject: Education and training
subject: Epidemiology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Illustrate imaging findings of benign and malignant bone tumors and their typical distribution in the skeleton; Review of the prevalence and age group of the more frequent bone tumors; Non-tumor bone lesions will also be mentioned, which to some...
title: Observer variability in accept/reject classification of clinical image quality in mammography
Creators: name: Whelehan, Patsy
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Quality assurance
subject: Observer performance
subject: Mammography
subject: Breast

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Image quality in mammography is widely accepted to be an important factor in the detection of breast cancer, and published evidence provides some support for this almost self-evident position[1,2].Robust decision-making on when an image is of...
Publication boost in Web of Science journals and its effect on citation distributions
Creators: name: Šubelj, Lovro
name: Fiala, Dalibor
Publisher: name: arXiv
Year: 2016
Subjects: subject: Digital Libraries (cs.DL)
subject: Social and Information Networks (cs.SI)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: In this paper we show that the dramatic increase in the number of research articles indexed in the Web of Science database impacts the commonly observed distributions of citations within these articles. First, we document that the growing number of physics articles in recent years is due to existing journals publishing more and more papers rather than more new journals coming into being as it happens in computer science. And second, even though the references from the more recent papers generally cover a longer time span, the newer papers are cited more frequently than the older ones if the uneven paper growth is not corrected for. Nevertheless, despite this change in the distribution of citations, the citation behavior of scientists does not seem to have changed.
description: 14 pages, 5 figures, J. Assoc. Inf. Sci. Tec. (2016)
Three-Dimensional Wind Profile Prediction with Trinion-Valued Adaptive Algorithms
Creators: name: Gou, Xiaoming
name: Liu, Zhiwen
name: Liu, Wei
name: Xu, Yougen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: The problem of three-dimensional (3-D) wind profile prediction is addressed based a trinion wind model, which inherently reckons the coupling of the three perpendicular components of a wind field. The augmented trinion statistics are developed and employed to enhance the prediction performance due to its full exploitation of the second-order statistics. The proposed trinion domain processing can be regarded as a more compact version of the existing quaternion-valued approach, with a lower computational complexity. Simulations based on recorded wind data are provided to demonstrate the effectiveness of the proposed methods.
description: 4 pages, 4 figures, to be published in Proc. of the IEEE International Conference on Digital Signal Processing, Singapore, July 2015
Electroanalytical determination of Allura Red in beverage samples using an anodically pretreated graphite electrode
Creators: name: Uruc, Selen
name: Gorduk, Ozge
name: Sahin, Yucel
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 19999
subject: Mathematical Sciences not elsewhere classified

description: In this study, an anodically pretreated pencil graphite electrode (Ptre/PGE) which has oxygen-containing groups was used for the electrochemical determination of Allura Red (AR) by differential pulse voltammetry (DPV) method for the first time in the literature. In order to be more selective and sensitive the pencil graphite electrode, the anodic pretreatment process was performed by applying a constant +1.8 V potential for 250 s in pH 9 phosphate buffer solution using chronoamperometry method. The characterisation studies of the sensor were performed using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and atomic force microscopy (AFM) methods. Interference effects of sunset yellow, tartrazine, amaranth, aspartame, glucose, gelatin, and ascorbic acid on AR determination with Ptre/PGE were investigated. The limit of detection and quantitation values was found as 75 and 251 nmol L−1, respectively. The Ptre/PGE has been used for the determination of AR in cherry juice and energy drink samples, where it provides recovery ranging from 98.40% to 100.8%.
title: Spinal dysraphism with fat: MRI slices before the surgeon’s cut
Creators: name: Prakash, Meenakshi
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Neuroradiology spine
subject: MR
subject: Structured reporting
subject: Education
subject: Imaging sequences
subject: Congenital
subject: Education and training
subject: Outcomes

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Learning Objectives: The purpose of our educational exhibit is to : Describe the Magnetic Resonance Imaging (MRI) features of spinal dysraphism with fat. Classify the various types of lipomatous spinal dysraphism. Describe the reporting points the...
International Compensation Mechanisms for Foreign Investment Losses Due to Government Actions: A Multilateral Approach
Creators: name: Amoozadeh Mahdiraji, Hanif
name: Behbahani, Hossein
Publisher: name: Zenodo
Year: 2021

description: The article delves into the complex relationship between Iran and the United States, mainly focusing on the "JCPOA" and subsequent developments. This relationship has captured the attention of experts and researchers in political science, international relations, and international law. The core concern revolves around devising mechanisms that can ensure trust and reliability in government behavior within the realm of international relations and treaties. Despite acknowledging the prevalent skepticism regarding governments' trustworthiness in international politics, many theorists, including some pessimistic realists, argue for the necessity of establishing more stable mechanisms to achieve lasting peace in today's era. This article addresses a fundamental question about Iran-US relations: what will be the implications for Iran and foreign investment within the country if the United States withdraws from the JCPOA again? Can Iran's society and economy endure another setback? In this preliminary exploration, we aim to answer the question: "In current international law, what provisions exist to mitigate the risks associated with investing in foreign countries amidst political uncertainties?" Numerous measures and strategies have been devised in response to this question. However, these mechanisms and assurances typically come into play when the host government's actions harm the foreign investor. While various arrangements exist, there's no singular mechanism designed to address the actions of a third country in response to the host government's behavior. These arrangements typically involve guaranteeing the enforcement of arbitration decisions from courts handling disputes between foreign investors and the host government, as well as compensation funds and insurance. Subsequently, this article delves into examining and analyzing the broader policy options and potential solutions related to the aforementioned issue.
Limits on Foreground Subtraction from Chromatic Beam Effects in Global Redshifted 21 cm Measurements
Creators: name: Mozdzen, Thomas J.
name: Bowman, Judd D.
name: Monsalve, Raul A.
name: Rogers, Alan E. E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Foreground subtraction in global redshifted 21 cm measurements is limited by frequency-dependent (chromatic) structure in antenna beam patterns. Chromatic beams couple angular structures in Galactic foreground emission to spectral structures that may not be removed by smooth functional forms. We report results for simulations based on two dipole antennas used by the Experiment to Detect the Global EoR Signature (EDGES). The residual levels in simulated foreground-subtracted spectra are found to differ substantially between the two antennas, suggesting that antenna design must be carefully considered. Residuals are also highly dependent on the right ascension and declination of the antenna pointing, with RMS values differing by as much as a factor of 20 across pointings. For EDGES and other ground-based experiments with zenith pointing antennas, right ascension and declination correspond directly to the local sidereal time and the latitude of the deployment site, hence chromatic beam effects should be taken into account when selecting sites. We introduce the "blade" dipole antenna and show, via simulations, that it has better chromatic performance than the "fourpoint" antenna previously used for EDGES. The blade antenna yields 1-5~mK residuals across the entire sky after a 5-term polynomial is removed from simulated spectra, whereas the fourpoint antenna typically requires a 6-term polynomial for comparable residuals. For both antennas, the signal-to-noise ratio of recovered 21 cm input signals peaks for a 5-term polynomial foreground fit given realistic thermal noise levels.
description: 12 pages. 9 figures
ENLACE: Physical Activity (PA) Group Intervention Program
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: Enlace
Latino
Latina
Hispanic
women
promotora
community outreach
physical activity
border
rural
exercise
fitness
South Texas
intervention
protocol
PA

description: The study “ENLACE: A Promotora-Led Physical Activity Intervention Trial for Latinas in Texas” is a clinical trial (NCT00869583) funded by the National Institute of Health (NIH) (R01HL111718).
description: This record includes the curriculum guide and other materials for the intervention delivery for ENLACE participants randomized into the Physical Activity group. This includes a program curriculum, a difficulty scale; yoga flash cards, muscle strengthening flashcards; and a physical activity toolbox. All study materials are available in English and Spanish.
title: Direct puncture approach for embolization of visceral aneurysms.
Creators: name: Dik, Alex
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Aneurysms
subject: Embolisation
subject: Ultrasound
subject: Fluoroscopy
subject: Interventional vascular
subject: Arteries / Aorta

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Introduction Aneurysms along the visceral arteries can be split into 2 categories; visceral artery aneurysms (VAA) or “real” aneurysms and visceral artery pseudo-aneurysms (VAPA) or “false” aneurysms. The VAA are mainly caused by systemic...
title: Post EVAR Complication Rates: A Retrospective Review
Creators: name: Nicholas, Christopher
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Arteries / Aorta
subject: Catheter arteriography
subject: CT-Angiography
subject: Arterial access
subject: Audit and standards
subject: Stents
subject: Aneurysms

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Investigate endoleak and other complication rates of endovascular aneurysmrepair (EVAR) in our centre and compare to that of the literature. Determine if aneurysm neck anatomy influences the rate of type Ia...
Armed Forces Cooperation Foundations: Foundation or Co-op? (Feasibility of transforming the cooperation foundations of the armed forces into a co-op company)
Creators: name: Amoozadeh Mahdiraji, Hanif
Publisher: name: Zenodo
Year: 2022

description: Armed forces ‘cooperation foundations’, despite carrying the co-op name, have a different nature from other co-op sector entities. All persons in the cooperative sector, including co-op companies, cooperative unions, and cooperative chambers, precisely follow the seven principles of cooperatives, especially democratic governance. However, the ‘cooperation foundations’ of the armed forces are not similar to the cooperative in this respect, and they find affinities with this sector only from the point of view of the goals and benefiting from the benefits of the cooperative sector. Apart from the question about the nature of these institutions and their relationship with the cooperative sector, the issue has also been raised regarding whether these institutions can deepen their relationship with the cooperative sector. Can these foundations, in addition to the role of support, increase their supervisory and management role in the cooperatives of employees under the armed forces? To answer these questions, a description of the structure of the armed forces employees' cooperatives and their types in Iran and the world has been given. Then, according to the international experiences and the possibilities of the current law, suggestions have been presented, and the author thinks the third suggestion is a more suitable option for the foundations of the armed forces. In this proposal, it is mentioned that the cooperative foundations of the armed forces can go through the process of transforming themselves into non-governmental public institutions and join the law on the ‘List of Public Non-governmental Institutions’. Then, a single cooperative is formed as a cooperative group. These non-governmental public institutions as shareholders buy 49% of the co-op shares (in three forms of investment and without voting rights, non-member shareholding, and a maximum of 35% of voting rights, or public cooperative company and 49% of the voting rights). Other cooperatives of armed forces employees, including housing, consumption, and credit, have 51% of the additional shares (about a public cooperative, a part of this amount of shares must be offered on the stock exchange for natural persons Be considered).
title: Von Hippel Lindau syndrome: A pictorial review
Creators: name: Benzina, Neila
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: CNS
subject: Pancreas
subject: Kidney
subject: MR
subject: CT
subject: Diagnostic procedure
subject: Screening
subject: Pathology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Recognize the imaging appearances of the mainmanifestations of VHL disease. 2. Discuss the most appropriate screening investigations for VHL disease and the role of radiologic...
ENLACE: Community Health & Safety (CHS) Group Maintenance Program
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: Enlace
Latino
Latina
Hispanic
women
promotora
community outreach
physical activity
border
rural
exercise
fitness
South Texas
maintenance
protocol
community health and safety
CHS

description: The study “ENLACE: A Promotora-Led Physical Activity Intervention Trial for Latinas in Texas” is a clinical trial (NCT00869583) funded by the National Institute of Health (NIH) (R01HL111718).
description: This record includes the protocol for the delivery of the maintenance program for ENLACE participants randomized into the Community Health and Safety(CHS) group. This manual has three sections: (1) CHS Maintenance Protocol; (2) Participant Starter Pack; and (3) CHS Visit and Telephone Contact Materials.
Molecular docking-based interaction studies on imidazo[1,2-a] pyridine ethers and squaramides as anti-tubercular agents
Creators: name: Ahmed, S.
name: Prabahar, A.E.
name: Saxena, A.K.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 80699
subject: Information Systems not elsewhere classified
subject: Cancer

description: Development of new anti-tubercular agents is required in the wake of resistance to the existing and newly approved drugs through novel-validated targets like ATP synthase, etc. The major limitation of poor correlation between docking scores and biological activity by SBDD was overcome by a novel approach of quantitatively correlating the interactions of different amino acid residues present in the target protein structure with the activity. This approach well predicted the ATP synthase inhibitory activity of imidazo[1,2-a] pyridine ethers and squaramides (r = 0.84) in terms of Glu65b interactions. Hence, the models were developed on combined (r = 0.78), and training (r = 0.82) sets of 52, and 27 molecules, respectively. The training set model well predicted the diverse dataset (r = 0.84), test set (r = 0.755), and, external dataset (rext = 0.76). This model predicted three compounds from a focused library generated by incorporating the essential features of the ATP synthase inhibition with the pIC50 values in the range of 0.0508–0.1494 µM. Molecular dynamics simulation studies ascertain the stability of the protein structure and the docked poses of the ligands. The developed model(s) may be useful in the identification and optimization of novel compounds against TB.
Gene expression dynamics with stochastic bursts: exact results for a coarse-grained model
Creators: name: Lin, Yen Ting
name: Doering, Charles R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: We present a theoretical framework to analyze the dynamics of gene expression with stochastic bursts. Beginning with an individual-based model which fully accounts for the messenger RNA (mRNA) and protein populations, we propose a novel expansion of the master equation for the joint process. The resulting coarse-grained model reduces the dimensionality of the system, describing only the protein population while fully accounting for the effects of discrete and fluctuating mRNA population. Closed form expressions for the stationary distribution of the protein population and mean first-passage times of the coarse-grained model are derived and large-scale Monte Carlo simulations show that the analysis accurately describes the individual-based process accounting for mRNA population, in contrast to the failure of commonly proposed diffusion-type models.
description: 5 pages, 4 figures
Comparative Analysis of Family Policies: A Focus on the Islamic Republic of Iran in Relation to the German and British Contexts
Creators: name: Amoozadeh Mahdiraji, Hanif
Publisher: name: Zenodo
Year: 2016

description: The human drive to establish and sustain familial bonds should be acknowledged as a significant hallmark within the realm of human social interaction. The family unit constitutes the initial social institution a child becomes acquainted with, serving as their introduction to society at large. The paramount importance and central role of family life within human social dynamics underscore the necessity to accord it due priority within the scope of our capabilities. However, scholarly exploration of the family, as a subject of investigation, has been relatively brief compared to other branches within the domain of social sciences. The domain of family policy, as an integral component of social and public policy, emerged only a few decades ago. Despite this, articulating a comprehensive conceptual framework for family policy continues to encounter challenges. In the context of Iran, although the body of literature concerning public policy and social policy has been steadily expanding, discourse pertaining to family policy has remained largely overlooked. The predominant focus within this field has been on published works generated by researchers in the realm of social sciences, particularly those dedicated to women's and gender studies. While these works encompass discussions regarding the family, they often display a notable deficiency in adequately addressing the role and influence of the government—the chief architect of policy formulation. In light of these circumstances, the present report endeavors to employ a comparative approach, utilizing two analytical tools, to assess the status of family policies in respective countries. The goal is to ascertain their alignment with the welfare systems instituted by each government, shedding light on prevailing orientations associated with family policies within the geographical areas under examination. These proposed tools are posited as an initial step toward enhancing comprehension of family policies. Ultimately, the report seeks to conduct a comparative analysis, juxtaposing family policies across three nations: Germany and Great Britain recognized as vanguards in global welfare regimes, and the Islamic Republic of Iran.
ENLACE: Physical Activity (PA) Group Maintenance Program
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: Enlace
Latino
Latina
Hispanic
women
promotora
community outreach
physical activity
PA
maintenance
protocol
border
rural
exercise
fitness
South Texas

description: The study “ENLACE: A Promotora-Led Physical Activity Intervention Trial for Latinas in Texas” is a clinical trial (NCT00869583) funded by the National Institute of Health (NIH) (R01HL111718).
description: This record includes the protocol for the delivery of the maintenance program for ENLACE participants randomized into the Physical Activity (PA) group. This manual has three sections: (1) PA Maintenance Protocol; (2) PA Starter Pack; and (3) PA Visit and Telephone Contact Materials.
title: Systemic sclerosis – radiologic evaluation!
Creators: name: Pereira, Ana
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Lung
subject: Gastrointestinal tract
subject: CT
subject: Diagnostic procedure
subject: Barium meal
subject: Connective tissue disorders

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Review the clinical manifestations. Discuss and illustrate the imaging findings in multisystem involvement of systemic...
title: Acute disseminated encephalomyelitis in children: a regional institution experience of 35 patients
Creators: name: laadhari, mouna
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Inflammation
subject: Infection
subject: Acute
subject: Imaging sequences
subject: MR
subject: Paediatric
subject: Neuroradiology brain
subject: CNS

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: describe clinical, laboratory, neuroimaging features, treatment and outcome of ADEM in a Tunisian cohort. undertake a systematic review of published ADEM pediatric...
title: Ultrasonographic Evaluation of Kidney Transplant
Creators: name: Nascimento, Lucia
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Transplantation
subject: Education
subject: Diagnostic procedure
subject: Ultrasound-Spectral Doppler
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Kidney
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To demonstrate the role of triplex ultrasonography (US) in the evaluation of the renal transplant. To review and illustrate the normal post-operative findings and possible complications detected by triplex...
Certified Context-Free Parsing: A formalisation of Valiant's Algorithm in Agda
Creators: name: Bernardy, Jean-Philippe
name: Jansson, Patrik
Publisher: name: arXiv
Year: 2016
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: F.4.1; F.4.2

description: Valiant (1975) has developed an algorithm for recognition of context free languages. As of today, it remains the algorithm with the best asymptotic complexity for this purpose. In this paper, we present an algebraic specification, implementation, and proof of correctness of a generalisation of Valiant's algorithm. The generalisation can be used for recognition, parsing or generic calculation of the transitive closure of upper triangular matrices. The proof is certified by the Agda proof assistant. The certification is representative of state-of-the-art methods for specification and proofs in proof assistants based on type-theory. As such, this paper can be read as a tutorial for the Agda system.
A Robin Hood for all: a conjoint experiment on support for basic income
Creators: name: Rincon, Leire
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Support for universal basic income is one of the key conundrums of the politics of welfare reform. Research shows that the predictors of UBI favourability also explain support for other policy alternatives, which differ substantially from a UBI, like targeted or conditional cash transfers. What is attractive or objectionable about a UBI to individuals, and which policy alternatives does public opinion actually prefer? In this paper, I tackle these questions with a conjoint experiment conducted in Spain. The results show that the universality of UBI, i.e., the fact that it is given to everyone, is what generates opposition. On the other hand, its unconditionality or the idea that it does not attach any conditions to recipients, is not particularly unpopular. However, the results also reveal that progressive funding mechanisms and restricting eligibility criteria to citizens only, can boost approval for this policy. These results have far-reaching implications for the study of welfare preferences, UBI support and theories on deservingness.
Quantum Hall effect with small numbers of vortices in Bose-Einstein condensates
Creators: name: Byrnes, Tim
name: Dowling, Jonathan P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: When vortices are displaced in Bose-Einstein condensates (BEC), the Magnus force gives the system a momentum transverse in the direction to the displacement. We show that Bose-Einstein condensates (BEC) in long channels with vortices exhibit a quantization of the current response with respect to the spatial vortex distribution. The quantization originates from the well-known topological property of the phase around a vortex --- it is an integer multiple of $ 2 π$. In a similar way to the integer quantum Hall effect, the current along the channel is related to this topological phase, and can be extracted from two experimentally measurable quantities: the total momentum of the BEC and the spatial distribution. The quantization is in units of $ m/2h $, where $ m $ is the mass of the atoms and $ h $ is Planck's constant. We derive an exact vortex momentum-displacement relation for BECs in long channels under general circumstances. Our results presents the possibility that the configuration described here can be used as a novel way of measuring the mass of the atoms in the BEC using a topological invariant of the system. If an accurate determination of the plateaus are experimentally possible, this gives the possibility of a topological quantum mass standard and precise determination of the fine structure constant.
Observing Gravitational Waves From The Post-Merger Phase Of Binary Neutron Star Coalescence
Creators: name: Clark, James Alexander
name: Bauswein, Andreas
name: Stergioulas, Nikolaos
name: Shoemaker, Deirdre
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We present an effective, low-dimensionality frequency-domain template for the gravitational wave signal from the stellar remnants from binary neutron star coalescence. A principal component decomposition of a suite of numerical simulations of binary neutron star mergers is used to construct orthogonal basis functions for the amplitude and phase spectra of the waveforms for a variety of neutron star equations of state and binary mass configurations. We review the phenomenology of late merger / post-merger gravitational wave emission in binary neutron star coalescence and demonstrate how an understanding of the dynamics during and after the merger leads to the construction of a universal spectrum. We also provide a discussion of the prospects for detecting the post-merger signal in future gravitational wave detectors as a potential contribution to the science case for third generation instruments. The template derived in our analysis achieves $>90\%$ match across a wide variety of merger waveforms and strain sensitivity spectra for current and potential gravitational wave detectors. A Fisher matrix analysis yields a preliminary estimate of the typical uncertainty in the determination of the dominant post-merger oscillation frequency $f_{\mathrm{peak}}$ as $δf_{\mathrm{peak}} \sim 50$Hz. Using recently derived correlations between $f_{\mathrm{peak}}$ and the neutron star radii, this suggests potential constraints on the radius of a fiducial neutron star of $\sim 220$\,m. Such measurements would only be possible for nearby ($\sim 30$Mpc) sources with advanced LIGO but become more feasible for planned upgrades to advanced LIGO and other future instruments, leading to constraints on the high density neutron star equation of state which are independent and complementary to those inferred from the pre-merger inspiral gravitational wave signal.
title: Breast doses in CT: Phantom study
Creators: name: Bor, Dogan
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Dosimetric comparison
subject: Dosimetry
subject: CT
subject: Radiation physics

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The first aim of this work is to compare the breast doses received during the thorax examinations performed with nine different CT systems. An adult female anthropomorphic thorax phantom was scanned with and without automatic dose modulation...
ENLACE: Intervention Mapping
Creators: name: Institute, Latino Research
Publisher: name: The University of Texas at Austin
Year: 2024
Subjects: Enlace
Latino
Latina
Hispanic
women
promotora
community outreach
physical activity
border
rural
exercise
fitness
South Texas
planning
intervention

description: The study “ENLACE: A Promotora-Led Physical Activity Intervention Trial for Latinas in Texas” is a clinical trial (NCT00869583) funded by the National Institute of Health (NIH) (R01HL111718).
description: This record includes the intervention mapping logic model and behavioral outcome matric for the ENLACE study.
title: Anatomical considerations for C2 pedicle screw placement- A computerized tomographic study
Creators: name: Kala, Prachi
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Patterns of Care
subject: Normal variants
subject: Diagnostic procedure
subject: CT
subject: CNS
subject: Anatomy

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Transpedicular screw placement for the second cervical pedicle is a challenge to neurosurgeons due its close proximity to the neurovascular structures. The purpose of this study was To Define the true C2 Pedicle- the segment that joins the posterior...
Ab initio transport results for strongly correlated fermions
Creators: name: Schlünzen, N.
name: Hermanns, S.
name: Bonitz, M.
name: Verdozzi, C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Quantum transport of strongly correlated fermions is of central interest in condensed matter physics. Here, we present first-principle nonequilibrium Green functions results using $T$-matrix selfenergies for finite Hubbard clusters of dimension $1,2,3$. We compute the expansion dynamics following a potential quench and predict its dependence on the interaction strength and particle number. We discover a universal scaling, allowing an extrapolation to infinite-size systems, which shows excellent agreement with recent cold atom diffusion experiments [Schneider et al., Nat. Phys. 8, 213 (2012)].
title: The role of diffusion-weighted magnetic resonance imaging in T staging and grading of Urinary Bladder cancer
Creators: name: Abdel-Rahman, Hossam
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Urinary Tract / Bladder
subject: MR-Diffusion/Perfusion
subject: Staging
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Purpose: To evaluate the ability of diffusion-weighted imaging (DWI) in T staging of bladder cancer and the correlation between the apparent diffusion coefficient (ADC) and tumor...