cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states
Creators: name: Daburon, Sophie
name: Furman, David
name: Lartigue, Lydia
name: Spitzer, Matthew H
name: Fragiadakis, Gabriela K
name: Moreau, Jean-François
name: Nolan, Garry P
name: Déchanet-Merville, Julie
name: Douchet, Isabelle
name: Ganio, Edward A
name: Bolen, Christopher R
name: Faustin, Benjamin
name: Blanco, Patrick
name: Davis, Mark M
name: Dekker, Cornelia L
name: Chang, Junlei
name: Jojic, Vladimir
name: Haddad, François
name: Gaudilliere, Brice
name: Kuo, Calvin J
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear. Inflammasomes can drive chronic inflammation in the context of an infectious disease or cellular stress, and they trigger the maturation of interleukin-1β (IL-1β). Here we find that the expression of specific inflammasome gene modules stratifies older individuals into two extremes: those with constitutive expression of IL-1β, nucleotide metabolism dysfunction, elevated oxidative stress, high rates of hypertension and arterial stiffness; and those without constitutive expression of IL-1β, who lack these characteristics. Adenine and N4-acetylcytidine, nucleotide-derived metabolites that are detectable in the blood of the former group, prime and activate the NLRC4 inflammasome, induce the production of IL-1β, activate platelets and neutrophils and elevate blood pressure in mice. In individuals over 85 years of age, the elevated expression of inflammasome gene modules was associated with all-cause mortality. Thus, targeting inflammasome components may ameliorate chronic inflammation and various other age-associated conditions.
‘Because thereon, in a great measure, depend the success and belief of their Office’: Clergy-lay relationships in Herefordshire, 1640-1700
Creators: name: Wessem, Elizabeth B. van
Publisher: name: University of Leicester
Year: 2023
Subjects: Uncategorized

description: Academic conversations concerning Keith Wrightson’s ‘Politics of the Parish’ have most recently included examinations of the clerical-lay relationship in order to better understand parochial networks: rarely have clergymen been considered holistically. Here, an exploration of that takes place. Examinations of clergymen as husbands, heads of households, and flawed individuals is undertaken as well as more conventional observations of religious and financial matters. Clerical relationships are examined in depth: in households, within and without the parish, between ordinary people and gentry, to highlight how important it was that ministers negotiate political settlements with their parishioners. The use of Wrightson’s parochial ‘spheres’ has allowed for an analysis of cases from the court of Instance in the Consistory Court of Hereford, and has enabled the incorporation of topics such as clerical ejection, tithes, officeholding, and pew disputes. In doing so, the thesis explores the way that clerical success depended on parochial belief in the effectiveness of his role. Such belief could be undermined — by the clergyman or his parishioners. Much depended on the denominational balance in the parish. Where Protestant Nonconformists were more prevalent, parishioners were more assertive in seeking redress in the courts. Clerical personality also dictated how disputes were resolved. Ministerial reputation could be affected by a failure to adhere to conventions of manly conduct, but also by an inability to meet parochial expectations of clerical conduct and success. Parochial quietude was such an expectation: best achieved by ministerial mediation, the parson would also have been aware that failure could negatively affect parochial perception of him. Individual clerical behaviour could critically influence a parish’s confidence in their minister, and from there, affect his success in his relationships with them. Clergymenwere lynchpins in parochial networks: without a functioning parson in that role, continued parochial government would be that much more difficult
Self-cancelation of a scalar in neutral meson mixing and implications for LHC
Creators: name: Nebot, M.
name: Silva, Joao P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Flavour changing neutral scalar interactions are a standard feature of generic multi Higgs models. These are constrained by mixing in the neutral meson systems. We consider situations where there are natural cancellations in such contributions. In particular, when the spin 0 particle has both scalar and pseudoscalar couplings, one may have a self-cancellation. We illustrate one such partial cancellation with BGL models. We also inquire whether the flavour changing quark interactions can lead to new production mechanisms for a neutral scalar at LHC.
description: RevTex, 16 pages, 4 figures. v2: PRD version
title: LIKE A RIVER NOT A STONE: A DESCRIPTIVE PHENOMENOLOGICAL PSYCHOLOGICAL STUDY OF THE CHINESE STUDENT EXPERIENCE OF GETTING AN EDUCATION AT NYU SHANGHAI IN RELATION TO THE LIBERAL ARTS APPROACH
Creators: name: Conlon, Brandon
Publisher: name: University of Liverpool Repository
Year: 2020

description: This study investigated the Chinese student experience of getting an education at NYU Shanghai. Four half-hour interviews were carried out with each of three student participants, who were asked to describe their experience of getting an education over their four undergraduate years at the university. On the basis of rich descriptions of the particular experiences provided by the three students, the research discovered one holistic phenomenological structure of the overall experience with eight component parts, called constituents. This structure and its component parts was then used to bring to light a variety of aspects of the experience within the particular cultural context of the university. The experience and its constituents were further considered in relation to enacting the espoused liberal arts values and mission of the university. The liberal arts as a cultural construct representing a specific set of educational values is explored in the literature review alongside the more general student experience and experience of Chinese students. Variations between the empirical experiences of the three students were described, surfacing insights about the experiences as they related to relevant scholarly literature on the student experience of the liberal arts, including liberal arts learning outcomes. The overall experience consisted of the following eight constituents 1) a pursuit of knowledge, skills, and the development of character through modes of exploration and investigation, 2) an awakening to changes within oneself and one’s lifeworld, 3) a growing consciousness of development, mastery, and limitations of knowledge and skill pertaining to the domain specific area of S’s major, 4) a growing consciousness of the transferability of knowledge, skills, and attributes to other domains, 5) social interactions, 6) comparison to things Chinese, 7) feelings of satisfaction and confidence, and 8) perceiving the exceptionalism and special features of NYU Shanghai. On the basis of these constituents and the reviewed literature of the liberal arts it was concluded that the experience was moderately, but not robustly, commensurable with a liberal arts approach to education. These findings contribute to understanding the way the liberal arts as a form of American educational culture is experienced, especially as it is exported and adopted in new global contexts, in this case the developing higher education landscape in China.
HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy
Creators: name: Cleary, Rachel A.
name: Richman, Douglas D.
name: Hudgens, Michael G.
name: Lada, Steven M.
name: Cao, Youfang
name: Ribeiro, Ruy M.
name: Baker, Caroline E.
name: Victor Garcia,
name: Thayer, William O.
name: Honeycutt, Jenna B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Despite years of fully suppressive antiretroviral therapy (ART), HIV persists in the host and is never eradicated. One major barrier to eradication is that multiple different cell types are infected that may individually contribute to HIV persistence. Tissue macrophages are critical contributors to HIV disease (1–3); however, their specific role in HIV persistence during long-term suppressive ART has not been established (4–6). Using humanized myeloid-only mice (MoM), we demonstrate that HIV infection of tissue macrophages is rapidly suppressed by ART, as determined by a rapid drop in plasma viral load and a dramatic drop in the levels of cell-associated viral RNA and DNA. No virus rebound was observed in the plasma of 67% of the ART treated animals at seven weeks post-ART interruption, and no replication competent virus was rescued from the tissue macrophages obtained from these animals. In contrast, in a subset of animals (~33%), a significantly delayed viral rebound was observed that is consistent with the establishment of persistent infection in tissue macrophages. These observations represent the first direct evidence of HIV persistence in tissue macrophages in vivo.
Supplemental Figures from Persistent cross-species SARS-CoV-2 variant infectivity predicted via comparative molecular dynamics simulation
Creators: name: Rajendran, Madhusudan
name: Babbitt, Gregory A.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: Widespread human transmission of SARS-CoV-2 highlights the substantial public health, economic and societal consequences of virus spillover from wildlife and also presents a repeated risk of reverse spillovers back to naive wildlife populations. We employ comparative statistical analyses of a large set of short-term molecular dynamic (MD) simulations to investigate the potential human-to-bat (genus Rhinolophus) cross-species infectivity allowed by the binding of SARS-CoV-2 receptor-binding domain (RBD) to angiotensin-converting enzyme 2 (ACE2) across the bat progenitor strain and emerging human strain variants of concern (VOC). We statistically compare the dampening of atom motion across protein sites upon the formation of the RBD/ACE2 binding interface using various bat versus human target receptors (i.e. bACE2 and hACE2). We report that while the bat progenitor viral strain RaTG13 shows some pre-adaption binding to hACE2, it also exhibits stronger affinity to bACE2. While early emergent human strains and later VOCs exhibit robust binding to both hACE2 and bACE2, the delta and omicron variants exhibit evolutionary adaption of binding to hACE2. However, we conclude there is a still significant risk of mammalian cross-species infectivity of human VOCs during upcoming waves of infection as COVID-19 transitions from a pandemic to endemic status.
A mechanism of baryogenesis for causal fermion systems
Creators: name: Finster, Felix
name: Jokel, Maximilian
name: Paganini, Claudio F.
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: fermiogenesis, baryogenesis, causal fermion system
subject: 510 Mathematik

description: It is shown that the theory of causal fermion systems gives rise to a novel mechanism of baryogenesis. This mechanism is worked out computationally in globally hyperbolic spacetimes in a way which enables the quantitative study in concrete cosmological situations.
Supplementary documentation for SAEON's field instrument data collected at the Cape Agulhas R43 Road Bridge station
Creators: name: South African Environmental Observation Network (SAEON) Fynbos Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cape Agulhas
Hydrological
Solinst depth, temperature and conductivity logger
water level
water temperature

description: This package contains supporting information for the hydrological data collected at Cape Agulhas's R43 Road Bridge station, as part of the South African Environmental Observation Network's monitoring projects.
Calculation of generalized spin stiffness constant of strongly correlated doped quantum antiferromagnet on two-dimensional lattice and it's application to effective exchange constant for semi-itinerant systems
Creators: name: Bhattacharjee, Suraka
name: Chaudhury, Ranjan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The generalized spin stiffness constant for a doped quantum antiferromagnet has been investigated both analytically and numerically as a function of doping concentration at zero temperature, based on the strongly correlated t-J model on two-dimensional square lattice. The nature of the theoretical dependence of the stiffness constant on doping shows a striking similarity with that of the effective exchange constant, obtained from the combination of other theoretical and experimental techniques in the low doping region. This correspondence once again establishes that spin stiffness can very well play the role of an effective exchange constant even in the strongly correlated semi-itinerant systems. Our theoretical plot of the stiffness constant against doping concentration in the whole doping region exhibits the various characteristic features like a possible crossover in the higher doping regions and persistence of short range ordering even for very high doping with the complete vanishing of spin stiffness occurring only close to 100% doping. Our results receive very good support from various other theoretical approaches and also brings out a few limitations of some of them. Our detailed analysis highlights the crucial importance of the study of spin stiffness for the proper understanding of magnetic correlations in a semi-itinerant magnetic system described by the strongly correlated t-J model. Moreover, our basic formalism can also be utilized for determination of the effective exchange constant and magnetic correlations for itinerant magnetic systems, in general in a novel way.
description: 18 pages, 6 figures
Blechnum laevigatum Cav., Descr. Pl.
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Blechnaceae
Blechnum
Blechnum laevigatum

description: Blechnum laevigatum Cav., Descr. Pl. 263. 1802.
 Range:— Bolivia (CH, CO, SC); across northwestern and central Argentina to Uruguay and southeastern Brazil.
 Ecology:— Locally uncommon; terrestrial in humid and semihumid forests, especially in damp sites among rocks and on banks; 300–2300 m.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XXXIII. Blechnaceae, pp. 99-117 in Phytotaxa 334 (2) on page 104, DOI: 10.11646/phytotaxa.334.2.1, http://zenodo.org/record/13721528
Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
Creators: name: Chen, Ting
name: Dai, Xiangpeng
name: Beck, Andrew H
name: Buser, Lorenz
name: Wei, Wenyi
name: Beca, Francisco
name: Wild, Peter J
name: Li, Xiaoning
name: Barbieri, Christopher E
name: Muthuswamy, Senthil K
name: Blattner, Mirjam
name: Liu, Pengda
name: Wang, Shangqian
name: Wong, Kwok-Kin
name: Zhang, Jinfang
name: Shimizu, Kouhei
name: Gan, Wenjian
name: Chen, Yu
name: Huang, Ling
name: Rubin, Mark A
name: Garraway, Levi A
name: Zhong, Qing
name: Liu, Shengwu
name: Qi, Jun
name: Zhang, Wei
name: Inuzuka, Hiroyuki
name: Huang, Jiaoti
name: Guo, Jianping
name: Wang, Liewei
name: Buckley, Dennis L
name: Bradner, James E
name: Vasudevan, Divya
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The bromodomain and extra-terminal (BET) family of proteins, comprised of four members including BRD2, BRD3, BRD4 and the testis-specific isoform BRDT, largely function as transcriptional co-activators 1–3 and play critical roles in various cellular processes, including cell cycle, apoptosis, migration and invasion 4,5. As such, BET proteins enhance the oncogenic functions of major cancer drivers by either elevating their expression such as c-Myc in leukemia 6,7 or by promoting transcriptional activities of oncogenic factors such as AR and ERG in the prostate cancer setting 8. Pathologically, BET proteins are frequently overexpressed and clinically linked to various types of human cancers 5,9,10, therefore pursued as attractive therapeutic targets for selective inhibition in patients. To this end, a number of bromodomain inhibitors, including JQ1 and I-BET, have been developed 11,12 and shown promising outcomes in early clinical trials. Despite resistance to BET inhibitor has been documented in pre-clinical models 13–15 the molecular mechanisms underlying acquired resistance are largely unknown. Here, we report that Cullin 3SPOP earmarks BET proteins including BRD2, BRD3 and BRD4 for ubiquitination-mediated degradation. Pathologically, prostate cancer-associated SPOP mutants fail to interact with and promote the destruction of BET proteins, leading to their elevated abundance in SPOP-deficient prostate cancer. As a result, prostate cancer cells and prostate cancer patient-derived organoids harboring SPOP mutations are more resistant to BET inhibitor-induced cell growth arrest and apoptosis. Therefore, our results elucidate the tumor suppressor role of SPOP in prostate cancer by negatively controlling BET protein stability, and also provide a molecular mechanism for BET inhibitor resistance in prostate cancer patients bearing SPOP mutations.
Soil analysis report in Kogelberg, site 3418BD
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Soil Analysis
Kogelberg

description: This is a scanned copy of a soil analysis report in Kogelberg, site 3418BD, including a map. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
Soil profile of Sonderend, Langeberg, site 3319DB/8
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
soil profile
Langeberg
Sonderend

description: This is a scanned copy of a soil profile including a diagram of Sonderend, Langeberg, site 3319DB/8. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
title: Encountering Threshold Concepts and Transformative Learning: Lessons from students’ study abroad experiences to enhance the internationalisation of teaching and learning for all students at a Dutch University of Applied Sciences
Creators: name: Johnson, Wayne
Publisher: name: University of Liverpool Repository
Year: 2021

description: Abstract The internationalisation of higher education remains one of the most important strategic priorities of universities all around the world. The continued shift towards globalisation compels universities to ensure their educational programmes and courses are designed to produce globally competent graduates. While universities invest in different approaches to achieve this goal, study abroad has become ubiquitous as a high-impact educational practice. The international learning outcomes associated with a study abroad experience have been extensively researched and well documented. Although study abroad produces much of the required learning outcomes desired for 21st-century graduates, its reach remains minuscule in the context of institution-wide teaching and learning. This research project has two aims. The first is to examine the transformative learning outcomes connected to study abroad supported by Mezirow’s transformative learning theory. The second is to extend the benefits emanating from a study abroad experience to the majority of students unable or unwilling to participate in study abroad by embedding them in the curriculum supported by the threshold concept theory and approach. Ten participants of the university’s study abroad programme were included in a qualitative investigation in which they shared their experiences through in-depth interviews. Data collection utilised the phenomenological research method to uncover the students’ unique perspectives of their experiences, which supported the researcher’s aim to better understand the phenomenon. The findings resonated with the extensive body of literature regarding the outcomes and benefits of participating in a study abroad experience. Three particular areas of growth and development experienced by the participants were highlighted by the findings. These outcomes are congruent with the universal objectives to which universities aspire for their graduates. In addition, the findings resulted in the identification of three threshold concepts that should be incorporated in curricula to enhance the internationalisation of teaching and learning. This research project presents possibilities for the university to extend the benefits and outcomes from a study abroad experience to all students regardless of their discipline. The threshold concepts approach identifies different ways in which the curriculum developers can embed these outcomes in the different study programmes. Finally, the research resulted in a model whereby the university can implement a comprehensive approach to teaching and learning the fundamental learning outcomes of a study abroad experience and extend them to all students. Keywords: Internationalisation, study abroad, transformative learning, threshold concepts, phenomenography.
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
Creators: name: Gieseck, Richard L.
name: Rimland, Casey A.
name: Karlsen, Tom H.
name: Justin, Alexander W
name: Saeb-Parsy, Kourosh
name: Tysoe, Olivia C
name: Markaki, Athina E.
name: Casey, John
name: Materek, Paulina M.
name: Zonneveld, Mariëlle C.F.
name: Berntsen, Natalie Lie
name: Upponi, Sara S
name: Georgakopoulos, Nikitas
name: Godfrey, Edmund M
name: Sinha, Sanjay
name: Hannan, Nicholas R.F.
name: Yiangou, Loukia
name: Bargehr, Johannes
name: Gómez-Vázquez, María J.
name: Ortmann, Daniel
name: Gelson, William T.H.
name: Shu, Wenmiao
name: Davies, Susan E.
name: Melum, Espen
name: Pedersen, Marianne T.
name: Vallier, Ludovic
name: Valestrand, Laura
name: Pawlowski, Matthias
name: Sawiak, Stephen
name: Simonic, Ingrid
name: Brown, Stephanie E.
name: Alexander, Graeme J.
name: Wynn, Thomas A.
name: Jensen, Kim B.
name: Skeldon, Gregor M.
name: Sampaziotis, Fotios
name: Ross, Alexander
name: De Brito, Miguel Cardoso
name: Snijders, Kirsten E
name: Bertero, Alessandro
name: Pirmadjid, Negar
name: Zilbauer, Matthias
name: Madrigal, Pedro
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The treatment of common bile duct (CBD) disorders, such as biliary atresia or ischemic strictures, is restricted by the lack of biliary tissue from healthy donors suitable for surgical reconstruction. Here we report a new method for the isolation and propagation of human cholangiocytes from the extrahepatic biliary tree in the form of extrahepatic cholangiocyte organoids (ECOs) for regenerative medicine applications. The resulting ECOs closely resemble primary cholangiocytes in terms of their transcriptomic profile and functional properties. We explore the regenerative potential of these organoids $\textit{in vivo}$ and demonstrate that ECOs self-organize into bile duct–like tubes expressing biliary markers following transplantation under the kidney capsule of immunocompromised mice. In addition, when seeded on biodegradable scaffolds, ECOs form tissue-like structures retaining biliary characteristics. The resulting bioengineered tissue can reconstruct the gallbladder wall and repair the biliary epithelium following transplantation into a mouse model of injury. Furthermore, bioengineered artificial ducts can replace the native CBD, with no evidence of cholestasis or occlusion of the lumen. In conclusion, ECOs can successfully reconstruct the biliary tree, providing proof of principle for organ regeneration using human primary cholangiocytes expanded $\textit{in vitro}$.
title: Continuing Medical Education (CME): An exploration of method in teaching empathy to first year residents in a Singapore hospital
Creators: name: Suppiah Cavert, Maleena
Publisher: name: University of Liverpool Repository
Year: 2020

description: Knowledge and skills can be taught. What of character or personality – can desirable personality traits like empathy be taught? Studies show that there is a deterioration of medical students’ and residents’ self-perceived empathy during clinical training. The first stage of the study aimed to compare the levels of empathy of Post-Graduate Year 1 (PGY1) doctors in a public hospital pre- and post-teaching. In complement, we explored the empathy learning experience of doctors in an environment with their colleagues from all job groups present. Stage 1 - Initial small-scale data was gathered in a mixed method study with 21 PGY1s (using the Jefferson Scale of Physician Empathy (JSPE), whilst their patients were asked to fill the Jefferson Scale of Patient Perceived Physician Empathy (JSPPPE). Equal and randomised test and control groups were formed. The test group of PGY1s were asked to view a teaching video online, after which they filled a qualitative reflective feedback form. The survey exercise was repeated to obtain post-intervention empathy scores. Findings: a heightened awareness about the doctor-patient relationship in the PGY1s who viewed the video; PGY1s’ self-assessed empathy levels do not correlate with their patients’ assessments. In Stage 2, using the classroom as a laboratory for teaching empathy, we explored what actually occurs during the learning and post-learning (reflection, practice change) experiences for doctors and their colleagues. Data was collected from five focus group discussions. The teaching of empathy is necessary in sustaining empathetic care throughout doctors’ training and career. Although some patients may not want empathy, we need to explore ways of arousing awareness of self and others, of curiosity, of imagination, and to promote reflection in practice – these contribute to restoring hope in humanistic care. Leaders in medical education and clinical tutors should closely monitor the hidden curriculum (and other organizational and systemic challenges) as well as ensure physician wellbeing whilst enacting a curriculum change in order to incorporate the teaching of empathy to residents, their peers, and colleagues.
Blechnum lanceola Sw., Kongl. Vetensk. Acad. Handl. 1817
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Blechnaceae
Blechnum
Blechnum lanceola

description: Blechnum lanceola Sw., Kongl. Vetensk. Acad. Handl. 1817 (1): 71, t. 3, f. 2. 1817.
 Range:— Peru to Bolivia (CH, CO, LP, SC); southeastern Brazil to eastern Paraguay and northeastern Argentina.
 Ecology:— Local and uncommon; on and among rocks along streams and near waterfalls, in humid forest habitats; to 1900 m.
 Notes:— Unless fertile leaves are seen, this may be mistaken for juvenile, sterile individuals of other species of Blechnum.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XXXIII. Blechnaceae, pp. 99-117 in Phytotaxa 334 (2) on page 104, DOI: 10.11646/phytotaxa.334.2.1, http://zenodo.org/record/13721528
Supplementary documentation for SAEON's field instrument data collected at the Cathedral Peak 9C station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cathedral Peak
Meteorological
Tipping bucket
Precipitation

description: This package contains supporting information for the meteorological data collected at Cathedral Peak's 9C station, as part of the South African Environmental Observation Network's monitoring projects.
title: Developing Equality in Merger of Equals: A Grounded-Theory Study
Creators: name: Srur, Haim Ygal
Publisher: name: University of Liverpool Repository
Year: 2021

description: The goals of this thesis are to explore and discover a new understanding of the underlying dynamics of Post-Merger Integration (PMI) that lead to equality during a merger within the researcher’s organisation and develop a framework for informed action. Starting with a broad research question of ‘what are the factors that influence the construction of equality during PMI?’ that was followed by a foundational literature review that shed light on the complexity of Merger and Acquisition (M&A) and the lack of a theoretical framework that can explain the equality construction during PMI. M&A was found to be suffered from a high rate of failure that derived from a lack of understanding of the PMI dynamics that unfold across the process and the impact of the human factors. Becoming an equal employee within the merged company was founded as a critical success factor but there is a lack of understanding of how equality is constructed and unfolded during the PMI. Applying Grounded Theory (GT) principles, using an iterative process of data collection through semi-structured interviews and theoretical sampling, constant comparison, and through theoretical coding discover an emerging theory grounded in data within the research field. Theoretical categories emerged to explain the basic social process of equality construct and how it unfolds during a PMI. Scholarly, at the core of the discovered theory is that individuals developed their equality perception as an unfolding process through the PMI. Theoretical conceptualisations put forth the elements of influence, meaning and justice as the precursors of equality construction. Within these three theoretical categories, the results showed how these categories unfold through the stages of the PMI that enable equality to be developed. Based on the substantive theory and the collective data, informed actionable knowledge was developed that generates actionable plans to overcome the disintegrative dynamics of PMI. Practically, the emergent theory and literature were the basis for developing actionable knowledge for short and long-term PMI strategies. This thesis concludes with a discussion on the implications for practice, research and suggestions for future research. This research about the merger of equals, contributed to the construction of theory about the unfolding dynamics of a PMI process that shape equality creation through the integration of two merged companies.
title: A CONDUCT RISK PERSPECTIVE TO INTERNAL AUDITING AN ACTION RESEARCH INQUIRY
Creators: name: Soh, Woongan
Publisher: name: University of Liverpool Repository
Year: 2025

description: This thesis presents a qualitative action research (AR) study conducted to answer the research question: How can the internal audit (IA) approach contribute to averting recurring misconduct and enhance conduct risk management in global markets activities? This research is conducted on a Southeast Asia-based financial institution that experienced recurring misconduct despite regular IA reviews. This AR contributes to on-going debates on professional misconduct through the development and implementation of a changed IA approach and identification of essential internal auditors’ attributes to address conduct risk, avert misconduct and strengthen conduct risk management. This study establishes that a conduct risk governance focus to internal auditing can stem recurring misconduct in the organization.
Blechnum malacothrix Maxon & C. V. Morton, Bull. Torrey Bot.
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Blechnaceae
Blechnum
Blechnum malacothrix

description: Blechnum malacothrix Maxon & C.V.Morton, Bull. Torrey Bot. Club 66: 40. 1939.
 Range:— Endemic to Bolivia (CH, CO, LP, SC), but likely to occur in southern Peru.
 Ecology:— Common; terrestrial in humid forests, especially along forest margins, in secondary forests and scrub, and in fields and plantations, also along streams and on earthen banks; (250–) 650–2350 m.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. XXXIII. Blechnaceae, pp. 99-117 in Phytotaxa 334 (2) on page 104, DOI: 10.11646/phytotaxa.334.2.1, http://zenodo.org/record/13721528
title: Robert von Planta 1864-1937
title: Erinnerungsblätter
titleType: Subtitle
Creators: name: (:Unkn) Unknown
Publisher: name: Zentralbibliothek Zürich
Year: 1942
Subjects: subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Planta, Robert von
subject: Alexandria
subject: Chur

description: Enthält: Vorwort von Gaudenz v. Planta; Trauerfeiern in Chur und Fürstenau am 15. und 16. Dezember 1937: Aus der Ansprache von Prof. Pfarrer B. Hartmann; Ansprache von Prof. Dr. J. Jud, im Namen der philologischen Kommission des Dicziunari Rumantsch Grischun; Ansprache von Dr. Raymund Vieli; Ein geschriebenes Freundes-Gedenkwort von Gustav Gamper; Zuschriften von Körperschaften; einzelne Stellen aus Nachrufen in der Presse; Robert und seine Eltern von Gdz. v. P.
Micro and nano patternable magnetic carbon
Creators: name: Sharma, Swati
name: Rostas, Arpad M.
name: MacKinnon, Neil
name: Bordonali, Lorenzo
name: Weber, Stefan
name: Korvink, Jan G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Carbon is conventionally not associated with magnetism, and much of the discussion of its nanotechnology perspectives appears to be centered on its electron transport properties. Among the few existing examples of magnetic carbon production, none has found a direct applicability in scalable micro and nano fabrication, Here we introduce a paramagnetic form of carbon whose precursor polymers can be lithographically patterned into micro and nano structures prior to pyrolysis. This unreactive and thermally robust material features strong room-temperature paramagnetism owing to a large number of unpaired electrons with restricted mobility, which is achieved by controlling the progression of bond dissociation and formation during pyrolysis. The manufacture of this magnetic carbon, having (3.97 x 0.8) 10^17 spins/ mg, can immediately benefit a number of spintronic and magnetic MEMS applications, and also shed light on the controversial theories concerning the existence and mechanisms of magnetism in carbon.
Municipio di Firenze. Il Sindaco Ubaldino Peruzzi a Luigi Ridolfi (22 maggio 1876)
Creators: name: Peruzzi, Ubaldino
name: Ridolfi, Luigi
Publisher: name: Zenodo
Year: 2023
Subjects: Accademia dei Georgofili
Peruzzi, Ubaldino
Ridolfi, Luigi
Lettera
Letter
Carteggio
Correspondence
1876

description: Lettera di Ubaldino Peruzzi a Segnatura dell’unità documentale: Archivio storico dell’Accademia dei Georgofili, Carteggio, Busta 37, 4961. Natura: manoscritto. Consistenza: cc. 3
description: Digitalizzato come parte della Mostra virtuale: Ubaldino Peruzzi : un percorso in rete : in occasione del bicentenario della nascita https://www.georgofili.it/contenuti/ubaldino-peruzzi-un-percorso-in-rete/17485
title: Empowering the people of God for the challenge of the Kingdom
Creators: name: Rae-Kelly, Anna
Publisher: name: University of Glasgow
Year: 1996
Subjects: subject: Spirituality, Kingdom of God, clergy, religion and society.

description: It is the intention of this research to examine current spiritual resources which attempt to empower the people of God. It will examine the need or otherwise for worship in the search for spirituality. It will investigate the impact of secularisation and explore the possibility of disempowerment of the people of God which could result from specific practices such as celibacy and restricted roles for women. It will examine the terms "marginalised" and "unchurched" in relation to the institutionalised church. It will present a critical assessment of recent surveys which highlight, figures detailing the growing number of distanced, unchurched and marginalised. Finally, it will set forth clearly and concisely the needs of these groups and show how meeting their needs allows them greater and more meaningful participation in the realisation of the kingdom of God. This study will endeavour to analyse the role of adult Christian formation/education , terms which will be defined, in servicing the needs of these groups. It will examine these areas as resources which might then serve to enhance the formation of the whole people of God including those unchurched and marginalised. Some of the theological topics highlighted herein, such subjects as the Trinity and the Kingdom of God, without doubt merit complete and independent theses in their own right. Nonetheless, in order to investigate the main themes of this study more fully, it has been necessary, albeit in summary form, that they be encompassed in order to contextualise fully the needs of the focus groups of this thesis. In conclusion, and in light of its assessment of how religious belief and practice now stands, this research will attempt to acknowledge specifically efforts currently being made to resource the focus groups of the study; to comment on the effectiveness or otherwise of these resources; and finally to propose an added solution by offering sample material, including a limited evaluation thereof, as a further resource to empower the people of God in the work of the Spirit towards the Kingdom.
Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader–Willi syndrome
Creators: name: Jiang, Yong-Hui
name: Everitt, Jeffrey I
name: Sciaky, Noah
name: Kim, Yuna
name: Roth, Bryan L
name: Xiong, Yan
name: Cao, Xinyu
name: Hulbert, Samuel W
name: Jin, Jian
name: Lee, Hyeong-Min
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Prader–Willi syndrome (PWS) is an imprinting disorder caused by a deficiency of paternally expressed gene(s) in the 15q11–q13 chromosomal region. The regulation of imprinted gene expression in this region is coordinated by an imprinting center (PWS-IC). In individuals with PWS, genes responsible for PWS on the maternal chromosome are present, but repressed epigenetically, which provides an opportunity for the use of epigenetic therapy to restore expression from the maternal copies of PWS-associated genes. Through a high-content screen (HCS) of >9,000 small molecules, we discovered that UNC0638 and UNC0642—two selective inhibitors of euchromatic histone lysine N-methyltransferase-2 (EHMT2, also known as G9a)—activated the maternal (m) copy of candidate genes underlying PWS, including the SnoRNA cluster SNORD116, in cells from humans with PWS and also from a mouse model of PWS carrying a paternal (p) deletion from small nuclear ribonucleoprotein N (Snrpn (S)) to ubiquitin protein ligase E3A (Ube3a (U)) (mouse model referred to hereafter as m+/pΔS−U). Both UNC0642 and UNC0638 caused a selective reduction of the dimethylation of histone H3 lysine 9 (H3K9me2) at PWS-IC, without changing DNA methylation, when analyzed by bisulfite genomic sequencing. This indicates that histone modification is essential for the imprinting of candidate genes underlying PWS. UNC0642 displayed therapeutic effects in the PWS mouse model by improving the survival and the growth of m+/pΔS−U newborn pups. This study provides the first proof of principle for an epigenetics-based therapy for PWS.
On the global symmetries of 6D superconformal field theories
Creators: name: Bertolini, Marco
name: Merkx, Peter R.
name: Morrison, David R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study global symmetry groups of six-dimensional superconformal field theories (SCFTs). In the Coulomb branch we use field theoretical arguments to predict an upper bound for the global symmetry of the SCFT. We then analyze global symmetry groups of F-theory constructions of SCFTs with a one-dimensional Coulomb branch. While in the vast majority of cases, all of the global symmetries allowed by our Coulomb branch analysis can be realized in F-theory, in a handful of cases we find that F-theory models fail to realize the full symmetry of the theory on the Coulomb branch. In one particularly mysterious case, F-theory models realize several distinct maximal subgroups of the predicted group, but not the predicted group itself.
description: 47 pages; v2: typos corrected, added the case su(6)* to the analysis of section 5 and section 6.1. v3: references added, minor changes, published version
Supplementary documentation for SAEON's field instrument data collected at the Jonkershoek 12B station
Creators: name: South African Environmental Observation Network (SAEON) Fynbos Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Jonkershoek
Meteorological
Tipping bucket rain gauge
Rainfall
air temperature

description: This package contains supporting information for the meteorological data collected at Jonkershoek's 12B station, as part of the South African Environmental Observation Network's monitoring projects.
Performance Comparison of UWB-Fingerprinting Positioning with RBF Neural Network and k-Nearest Neighbor in an Indoor Environment
Creators: name: Wipassorn Winitchaikul
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2012
Subjects: ultra wideband (UWB)
indoor positioning
radial basis function (RBF) neural network
k-nearest-neighbor (k-NN)

description: Journal of Information Science and Technology, 3, 1, 16-22
The Effects of Partial Occlusion in Image-based CAPTCHAs on Pass Rates
Creators: name: ฐปกรณ์ กฤษฎารักษ์
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2012
Subjects: CAPTCHA
imaged-based CAPTCHA
Gestalt Theory

description: Journal of Information Science and Technology, 3, 1, 23-32
Generalization of Clausius-Mossotti approximation in application to short-time transport properties of suspensions
Creators: name: Makuch, Karol
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: In 1983 Felderhof, Ford and Cohen gave microscopic explanation of the famous Clausius-Mossotti formula for the dielectric constant of nonpolar dielectric. They based their considerations on the cluster expansion of the dielectric constant, which relates this macroscopic property with the microscopic characteristics of the system. In this article, we analyze the cluster expansion of Felderhof, Ford and Cohen by performing its resummation (renormalization). Our analysis leads to the ring expansion for the macroscopic characteristic of the system, which is an expression alternative to the cluster expansion. Using similarity of structures of the cluster expansion and the ring expansion, we generalize (renormalize) the Clausius-Mossotti approximation. We apply our renormalized Clausius-Mossotti approximation to the case of the short-time transport properties of suspensions, calculating the effective viscosity and the hydrodynamic function with the translational self-diffusion and the collective diffusion coefficient. We perform calculations for monodisperse hard-sphere suspensions in equilibrium with volume fraction up to 45%. To assess the renormalized Clausius-Mossotti approximation, it is compared with numerical simulations and the Beenakker-Mazur method. The results of our renormalized Clausius-Mossotti approximation lead to comparable or much less error (with respect to the numerical simulations), than the Beenakker-Mazur method for the volume fractions below $ ϕ\approx 30\% $ (apart from a small range of wave vectors in hydrodynamic function). For volume fractions above $ϕ\approx 30 \%$, the Beenakker-Mazur method gives in most cases lower error, than the renormalized Clausius-Mossotti approximation.
Supplementary documentation for SAEON's field instrument data collected at the VASI A5 station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Vasi
Hydrological
Pressure transducer
Ground Water level

description: This package contains supporting information for the hydrological data collected at VASI's A5 station, as part of the South African Environmental Observation Network's monitoring projects.