cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The maximal rank conjecture and rank two Brill-Noether theory
Creators: name: Farkas, Gavril
name: Ortega, Angela
Publisher: name: arXiv
Year: 2010
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: We describe applications of Koszul cohomology to the Brill-Noether theory of rank 2 vector bundles. Among other things, we show that in every genus g>10, there exist curves invalidating Mercat's Conjecture for rank 2 bundles. On the other hand, we prove that Mercat's Conjecture holds for general curves of bounded genus, and its failure locus is a Koszul divisor in the moduli space of curves. We also formulate a conjecture concerning the minimality of Betti diagrams of suitably general curves, and point out its consequences to rank 2 Brill-Noether theory.
description: 21 pages. Title slightly changed, various minor corrections. To appear in Pure and Applied Mathematics Quarterly, volume dedicated to Eckart Viehweg
Fermion flavors in quaternion basis and infrared QCD
Creators: name: Furui, Sadataka
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: I analyze the lattice simulation data of the Domain Wall Fermion in quaternion basis. As pointed out by Atiyah and Ward, the minimum action solution for SU(2) Yang-Mills fields in Euclidean 4-space correspond, via Penrose twistor transform, to algebraic bundles on the complex projective 3-space. Assuming dominance of correlation between the fermions on the domain walls via exchange of instantons, I extract parameters necessary for defining gauge fields of Atiyah-Ward ansatz. The QCD effective coupling in the infrared and the relation between the number of flavors and the infrared fixed point is investigated. Consequence of this lepton flavor assignment to phenomenology of baryons is also discussed.
description: 18 pages, 15 figures
Urban Goods Movement: Problems, Opportunities and Future
Creators: name: Morehouse, J.E.
name: Markham, W.J.
name: Morehouse, J.E.
name: Markham, W.J.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
Teachers’ perspectives on the student-teacher relationship quality in female students with autism spectrum disorder
Creators: name: Lazo, Melissa
Publisher: name: University of British Columbia
Year: 2022

description: While the student-teacher relationship is highly associated with students' and teachers’ success and development, students with autism spectrum disorder (ASD) tend to have relationships characterized by higher levels of conflict and lower levels of closeness. Much of the research, however, has used primarily male samples when investigating ASD. This poses a risk to the generalizability of the findings to the female experience as studies have found that females with ASD tend to present different symptoms than males with ASD. The current study utilized a survey research design to examine Canadian elementary school teachers’ perceptions of the quality of their student-teacher relationship with their female students with ASD and its possible associations with teacher and student characteristics. Teachers in this study reported having low- quality relationships with their female students with ASD with high levels of conflict and dependency, and low levels of closeness. Results also indicate a negative correlation between teachers’ experience teaching and the student-teacher relationship quality. Neither previous exposure to individuals with ASD nor previous training in ASD were found to be associated with the student-teacher relationship quality. However, having specific training involving sex-related differences in ASD was associated with a more positive student-teacher relationship quality. Teachers’ confidence and knowledge in working with females with ASD were also associated with the student-teacher relationship quality. Additionally, student-related characteristics (e.g., social and communication skills symptom severity, internalizing and externalizing problems) were negatively correlated with the student-teacher relationship quality. Implications for research and practice, as well as future directions, are presented.
Multiple D4-D2-D0 on the Conifold and Wall-crossing with the Flop
Creators: name: Nishinaka, Takahiro
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Algebraic Geometry (math.AG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We study the wall-crossing phenomena of D4-D2-D0 bound states with two units of D4-brane charge on the resolved conifold. We identify the walls of marginal stability and evaluate the discrete changes of the BPS indices by using the Kontsevich-Soibelman wall-crossing formula. In particular, we find that the field theories on D4-branes in two large radius limits are properly connected by the wall-crossings involving the flop transition of the conifold. We also find that in one of the large radius limits there are stable bound states of two D4-D2-D0 fragments.
description: 24 pages, 4 figures; v2: typos corrected, minor changes, a reference added
Exploring mechanisms of T-cell acute lymphoblastic leukemia pathogenesis through molecular characterization of normal T-cell development
Creators: name: Wong, Alana Rachel
Publisher: name: University of British Columbia
Year: 2022

description: T-cell development and lineage commitment are temporally protracted processes in which the interplay between transcription factors and epigenetic modulators orchestrate the sequential exclusion of alternative fates and acquisition of specialized T-cell functions. Alterations during this process can lead to diseases such as T-cell acute lymphoblastic leukemia (T-ALL). While much work has focused on the transcription factors which drive normal development and T-ALL, the underlying epigenetic constraints remain poorly characterized. The central objective of the work presented in this thesis is to gain a greater understanding of the molecular events during early human T-cell differentiation to allow for dissection of particular genetic events that may occur in T-ALL. This was addressed through a detailed transcriptomic characterization of T-ALL within the framework of normal development, and through genetic perturbation and functional characterization of in vitro-differentiating T-cell subsets. The findings revealed; 1) an improved classification of T-ALL which better captures the developmental context in which specific transcription factors operate and which improves upon the identification of clinically relevant disease subgroups, and 2) novel insights into a role of DNMT3A in restricting lineage-specific signal responses in T-cell development and T-ALL. The results of functional assays revealed that DNMT3A loss increased signaling plasticity in T-lineage-restricted populations, as measured by response to cytokines typically affiliated with the myeloid lineage. This was enriched within a population of lineage-restricted T-cells expressing the G-, M-, and/or GM-CSF receptors, and was associated with proliferation and acquisition of a myeloid-like phenotype. Further investigation of the expression of these receptors revealed their prevalence in human T-ALL cell lines and post-natal thymus, thus indicating the biological relevance of CSF receptor expression in human tissues. Stimulation of the CSF receptor-expressing population by adding cognate ligands revealed a proliferative advantage in T-ALL cells, but only upon DNMT3A loss. These results suggest that DNMT3A may act to preclude response to alternative-lineage factors in T-cells, and furthermore point to a mechanism of selective advantage in a subset of T-ALL.
Coronal Shock Waves, EUV waves, and Their Relation to CMEs. I. Reconciliation of "EIT waves", Type II Radio Bursts, and Leading Edges of CMEs
Creators: name: Grechnev, V. V.
name: Uralov, A. M.
name: Chertok, I. M.
name: Kuzmenko, I. V.
name: Afanasyev, A. N.
name: Meshalkina, N. S.
name: Kalashnikov, S. S.
name: Kubo, Y.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We show examples of excitation of coronal waves by flare-related abrupt eruptions of magnetic rope structures. The waves presumably rapidly steepened into shocks and freely propagated afterwards like decelerating blast waves that showed up as Moreton waves and EUV waves. We propose a simple quantitative description for such shock waves to reconcile their observed propagation with drift rates of metric type II bursts and kinematics of leading edges of coronal mass ejections (CMEs). Taking account of different plasma density falloffs for propagation of a wave up and along the solar surface, we demonstrate a close correspondence between drift rates of type II bursts and speeds of EUV waves, Moreton waves, and CMEs observed in a few known events.
description: 30 pages, 15 figures. Solar Physics, published online. The final publication is available at http://www.springerlink.com
Review of available IT solutions for on-line educations
Creators: name: Borodo, Adam
name: Dębicka, Olga
name: Markiewicz, Magdalena
name: Galik, Anna
name: Reszka, Leszek
name: Reszka, Magdalena
Publisher: name: Zenodo
Year: 2023
Subjects: online education, IT software

description: Review of available IT solutions for on-line education, was prepared as part of the "Innovative competences in online higher education" (InCompEdu) project implemented by a consortium of 6 European universities from Croatia, Italy, Slovenia, Romania, Finland and Poland with the leading role of the University of Gdansk. The purpose of the publication is to present platforms and tools of ICT that can be used in online teaching, with a particular focus on higher education. This goal was achieved by preparing 5 chapters, which comprise, with an introduction, 87 pages of the study.
The Impact of Conglomerates on Domestic Transportation: An Empirical Assessment
Creators: name: Davis, G.M.
name: Dillard, J.E.
name: Davis, G.M.
name: Dillard, J.E.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
Inland Waterway User Charges: Preliminary Impact Estimates
Creators: name: Bronzini, Michael S.
name: Clark, WIlliam E.
name: Strack, Conrad W.
name: Bronzini, Michael S.
name: Clark, WIlliam E.
name: Strack, Conrad W.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
Coronal Shock Waves, EUV Waves, and Their Relation to CMEs. III. Shock-Associated CME/EUV Wave in an Event with a Two-Component EUV Transient
Creators: name: Grechnev, V. V.
name: Afanasyev, A. N.
name: Uralov, A. M.
name: Chertok, I. M.
name: Eselevich, M. V.
name: Eselevich, V. G.
name: Rudenko, G. V.
name: Kubo, Y.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: On 17 January 2010, STEREO-B observed in extreme ultraviolet (EUV) and white light a large-scale dome-shaped expanding coronal transient with perfectly connected off-limb and on-disk signatures. Veronig et al. (2010, ApJL 716, 57) concluded that the dome was formed by a weak shock wave. We have revealed two EUV components, one of which corresponded to this transient. All of its properties found from EUV, white light, and a metric type II burst match expectations for a freely expanding coronal shock wave including correspondence to the fast-mode speed distribution, while the transient sweeping over the solar surface had a speed typical of EUV waves. The shock wave was presumably excited by an abrupt filament eruption. Both a weak shock approximation and a power-law fit match kinematics of the transient near the Sun. Moreover, the power-law fit matches expansion of the CME leading edge up to 24 solar radii. The second, quasi-stationary EUV component near the dimming was presumably associated with a stretched CME structure; no indications of opening magnetic fields have been detected far from the eruption region.
description: 18 pages, 10 figures. Solar Physics, published online. The final publication is available at http://www.springerlink.com
Price Elasticities of Intercity Passenger Travel
Creators: name: Lave, C.A.
name: Mehring, J.
name: Kuzmyak, R.
name: Lave, C.A.
name: Mehring, J.
name: Kuzmyak, R.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
MOESM2 of Genome analyses of blaNDM-4 carrying ST 315 Escherichia coli isolate from sewage water of one of the Indian hospitals
Creators: name: Beg, Ayesha
name: Khan, Asad
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2: Table S1. Resistance genes associated with plasmid.
The U.S. Owner-Operator Trucker: A Transportation Policy Based on Personal Bankruptcy
Creators: name: Wyckoff, D. Daryl
name: Maiston, David H.
name: Wyckoff, D. Daryl
name: Maiston, David H.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
Bulk spectral functions in single and multi-scalar gravity duals
Creators: name: Springer, Todd
name: Gale, Charles
name: Jeon, Sangyong
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We examine two point correlation functions involving the trace of the energy momentum tensor in five dimensional gravity dual theories supported by one or more scalar fields. A prescription for determining bulk channel spectral functions is developed. This prescription generalizes previous work which centered on one scalar field. As an application of these techniques, we investigate the bulk spectral function and corresponding sum rule in the Chamblin-Reall background. We show that, when expressed in terms of the beta function, the sum rule for the Chamblin-Reall background can be written in a form similar to the sum rule in Yang-Mills theory.
description: 10 pages + appendices, 2 figures. v2: typos fixed and some text modified in Sec. V; conclusions unchanged. v3: Minor modifications, matches published version
Migrations transnationales et co-developpement entre Europe et Afrique: une etude sur le cas italo-senegalais
Creators: name: MBAYE, MAMADOU MOUSTAPHA
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: Les processus de migration, les d�s�quilibres et les in�galit�s internationales, la coop�ration (m�me d�centralis�e) et le co-d�veloppement ne sont pas seulement des processus interconnect�s mais n�cessitent une analyse empirique et interdisciplinaire. Dans le cas du volet migratoire et co-d�veloppement de la coop�ration italo-s�n�galaise, cette recherche doctorale diagnostique les politiques nationales et de la coop�ration et analyse l'intervention des diff�rentes cat�gories d?acteurs, en particulier, les organisations de migrants dans leur capacit� � mener des activit�s de co-d�veloppement et leur niveau d?implication. Elle analyse les forces et les faiblesses de la migration et du co-d�veloppement. Elle analyse des exp�riences de co-d�veloppement initi�es par les migrants ainsi que l?efficacit� des m�canismes de soutien � ces initiatives. On y rel�ve une grande h�t�rog�n�it� des acteurs, leurs d?intervention, les flux et niveaux de transferts de fonds, de comp�tences et la valorisation de produits et de cultures. Elle traite aussi les probl�mes d?efficacit� et d?efficience rencontr�es par les interventions men�es au titre de la coop�ration par les acteurs �tatiques et la rar�faction des ressources, la marginalisation des ONG et des associations de migrants relativement plus efficace dans leurs interventions au niveau local, les restrictions not�es dans la mobilit� de ces derniers, le d�ficit d?information des acteurs du co-d�veloppement. Par ailleurs, cette recherche a �tudi� l?implication des migrants dans les processus d?�laboration de politique publique en lien avec le co-d�veloppement et propose un mod�le de co-d�veloppement en lien avec les pratiques transnationales bas� sur une interaction entre le migrant et le niveau local de d�veloppement. La th�se aborde l?analyse de l?immigration s�n�galaise en Italie avec une attention particuli�re aux politiques migratoires et � la d�termination transnationale des processus migratoires. Aussi, le th�me de la coop�ration pour le d�veloppement est abord� sous la forme sp�cifique du � co-d�veloppement �, en analysant la contribution des migrants s�n�galais. La construction d?un mod�le de co-d�veloppement � servis d?identifier les bonnes pratiques � d�velopper pour renforcer le r�le des immigr�s s�n�galais dans le d�veloppement du pays d?origine.
Moduli of theta-characteristics via Nikulin surfaces
Creators: name: Farkas, Gavril
name: Verra, Alessandro
Publisher: name: arXiv
Year: 2011
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: We study moduli spaces of K3 surfaces endowed with a Nikulin involution and their image in the moduli space R_g of Prym curves of genus g. We observe a striking analogy with Mukai's well-known work on ordinary K3 surfaces. Many of Mukai's results have a very precise Prym-Nikulin analogue, for instance: (1) A general Prym curve from R_g is a section of a Nikulin surface if and only if g\leq 7, g\neq 6. (2) R_7 has the structure of a Mori fibre space over the corresponding moduli space of polarized Nikulin surfaces. (3) In the case of genus next to maximal (g=6), the Prym-Nikulin locus in R_6 is an extremal divisor; the corresponding space of Nikulin surfaces has a Grassmannian GIT model. (4) The Prym-Nikulin locus in R_g can be characterized by extra syzygies of Prym-canonical curves. We then use these results to study the geometry of the moduli space S_g of even spin curves, with special emphasis on the transition case of S_8 which is a 21-dimensional Calabi-Yau variety.
description: 26 pages. Final version to appear in Mathematische Annalen
PHYSICS WITH PHOTONS WITH THE ATLAS RUN 2 DATA: CALIBRATION AND IDENTIFICATION, MEASUREMENT OF THE HIGGS BOSON MASS AND SEARCH FOR SUPERSYMMETRY IN DI-PHOTON FINAL STATE.
Creators: name: MANZONI, STEFANO
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: The work presented in this manuscript is based on the proton-proton collision data from the Large Hadron Collider at a centre-of-mass energy of 13 TeV recorded by the ATLAS detector in 2015 and 2016. The research program of the ATLAS experiment includes the precise measurement of the parameters of the Standard Model (SM) and the search for signals of physics beyond the SM. Both these approaches are pursued in this thesis, which presents two different analyses. The first one is the measurement of the Higgs boson mass in the di-photon decay channel. The measured value of the mass is (125.11 � 0.42) GeV. Its combination with a similar measurement in the four lepton Higgs boson decay final state is presented. The value of the Higgs boson mass obtained from the combined measurement is (124.98 � 0.28) GeV. The second one is the search for production of supersymmetric particles (gluinos, squarks or winos) in a final state containing two photons and missing transverse momentum. No significant excess with respect to the SM background is observed and lower limits on the gluino, squark and wino masses are set in the context of a generalised model of gauge-mediated supersymmetry breaking with a bino-like next-to-lightest supersymmetric particle. Finally, ATLAS detector performance studies (electron and photon energy calibration and measurement of the photon->electron misidentification probability), which are key ingredients for the two analyses presented before, are also performed and described.
title: Young people returning to sentenced youth justice supervision 2019–20
Creators: name: Australian Institute of Health and Welfare
Publisher: name: Australian Institute of Health and Welfare
Year: 2021

description: Of young people aged 10–17 who were under sentenced youth justice supervision at some time between 2000–01 and 2019–20, 41% returned to sentenced supervision before turning 18. Of young people aged 10–16 in 2018–19 and released from sentenced community-based supervision, 38% returned to sentenced supervision within 6 months, and 54% within 12 months. Of those released from sentenced detention, 61% returned within 6 months, and 80% within 12 months.
Motor Carrier Planning: Regional Freight Demand for Common Carriers of General Freight
Creators: name: Nazem, Sufi
name: Peppers, Larry
name: German, H. Wade
name: Nazem, Sufi
name: Peppers, Larry
name: German, H. Wade
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
Clockwork plots : timekeeping narratives in Wilkie Collins's sensation fiction
Creators: name: Steele, Robert
Publisher: name: University of British Columbia
Year: 2022

description: Often considered founding texts of the sensation genre, Wilkie Collins’s novels of the 1860s have been identified with the perceived accelerated pace of modern life in the mid-nineteenth century. Indeed, Collins’s sensation fiction, which dominated the “sensational sixties,” emerged onto the literary scene in a time of temporal transition in Britain. The rapid industrialization of British labour combined with technological innovations in transportation and communication, such as rail travel and telegraphy, in the early nineteenth century necessitated the standardization of timekeeping in Britain, a process that began with the 1840 adoption of Greenwich Mean Time along rail lines, culminated in the 1880 adoption of Greenwich time as the legal standard across the United Kingdom, and structured daily life around clock time. Critics have read Collins’s novels as instilling the time discipline of standardized clock time in their plots, with their emphasis on timing, chronology, and suspense. Using Collins’s The Woman in White (1859–60) and Armadale (1864–66) as case studies of sensational temporality, my thesis complicates that reading, arguing that these novels resist time discipline by encoding contemporary concerns around standardized timekeeping and its dissonance with the heterogenous experience of personal time in both their representations of timekeeping and their narrative structures. Although the protagonists of these two novels adopt time discipline to unravel the villains’ carefully timed plots, the exigencies of clock time induce psychological breaks from temporal regularity, not only suggesting Collins’s critique of time discipline as mentally taxing but also positioning standardized time as a cultural construct that obscures more durational and personal temporal rhythms. Moreover, Collins’s sensational narrative strategies, such as timestamping, dilation, contraction, and suspense, as well as his metonymic representations of timepieces work together to critique an increasingly industrialized world, typified both by the contemporary attention to timekeeping and by the very serialized forms in which these novels were originally published. In doing so, Collins’s clockwork plots not only establish many of the time-sensitive conventions of the sensation genre but also point to a mid-nineteenth century preoccupation with the heterogeneity of time perception that prefigures late-nineteenth century psychological, philosophical, and literary discourses.
Discriminating the source of high-energy positrons with AMS-02
Creators: name: Pato, Miguel
name: Lattanzi, Massimiliano
name: Bertone, Gianfranco
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the prospects for discriminating between the dark matter (DM) and pulsar origin of the PAMELA positron excess with the Alpha Magnetic Spectrometer AMS-02. We simulate the response of AMS-02 to positrons (and electrons) originating from DM annihilations, and determine the pulsar parameters (spin-down luminosity, distance and characteristic age) that produce a satisfactory fit to the mock AMS-02 data. It turns out that it is always possible to mimic a DM signal with pulsars. Although the fit in some cases requires values of spin-down luminosity and characteristic age different from those of known pulsars in the ATNF and Fermi-LAT catalogues, these catalogues are known to be incomplete, and therefore the pulsar interpretation can hardly be ruled out. We also show that if the positron excess is due to a single pulsar, it is always possible to find a DM candidate that provides a good fit to the mock AMS-02 data. The discrimination between the two scenarios will thus require a better knowledge of the underlying sources, or complementary data.
description: 14 pages, 7 figures, 3 tables, matches published version
TEACHING STUDENTS THE ART OF EMBROIDERY AND ARTISTIC WEAVING IN EXTRACURRICULAR ACTIVITIES
Creators: name: Mukumova, Feruza
name: Baymurova, Nigora
Publisher: name: Zenodo
Year: 2023

description: The article provides samples of embroidery and artistic weaving of the Uzbek people. Methods for making jewelery and drawings are beingstudied, the thread is used, the fabrication is made from homemade cotton and cotton, the author gives the names of objects insufficient quantities that have survived in the oral speech of the local population of the Surkhan oasis. The traditional importance of weaving, embroidery in the life of young people.
A Pragmatic Analysis of the U.S. Maritime Policy: Its Impact on Marketing Costs
Creators: name: Rosenberg, L. Joseph
name: Davis, Grant M.
name: Rosenberg, L. Joseph
name: Davis, Grant M.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
ANALYSIS OF GENOMIC DATA IN RUMINANT SPECIES FOR PARENTAGE, PRODUCT TRACING AND POPULATION STRUCTURE STUDIES
Creators: name: TALENTI, ANDREA
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: The availability of genomic and high performance computing technologies gave access to new approaches and methods to exploit the high number of genetic information provided, even in livestock species. These new tools can be used to unveil the relationships between different populations or individuals, to understand the genetic background of breeds, to define the genetic architecture of phenotypes or pathologies and to detect selection signatures that shaped the cattle, sheep and goat reared today. In this context, these technologies may provide breeders and breeders? associations with new tools that may be used in livestock management. In fact, the estimation of genomic parentage among individuals can help in defining the least related animals in case of identical values of additive parentage and detect errors in pedigree declarations as well. Moreover, since DNA is immutable within animal life but very polymorphic between individuals, these tools may be of help in the definition of the breed or the individual of origin, improving food safety. In this thesis, I faced the complexity of genomic data in ruminant species, focusing in particular on goats. I reported three studies with distinct aims: i) study the signatures of selection in 369 animals of 16 Italian populations, and then focusing on the Valdostana goat breed which presents a breed-specific broad signature of selection in chromosome 7; ii) define a new method to develop panels of SNPs for parentage assessment that could be applied on species with unreliable genomic assembly; and iii) study the selection signatures in 929 animals of 41 Pakistani and Italian goat populations associated with a specific pigmentation pattern, the roan, detecting a candidate gene important in understanding the coat color genetics in goats and which could be also used as a marker for traceability of breeds that carry this peculiar phenotypic pattern.
Thermal evolution of massive compact objects with dense quark cores
Creators: name: Hess, Daniel
name: Sedrakian, Armen
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We examine the thermal evolution of a sequence of compact objects containing low-mass hadronic and high-mass quark-hadronic stars constructed from a microscopically motivated equation of state. The dependence of the cooling tracks in the temperature versus age plane is studied on the variations of the gaplessness parameter (the ratio of the pairing gap for red-green quarks to the electron chemical potential) and the magnitude of blue quark gap. The pairing in the red-green channel is modeled assuming an inhomogeneous superconducting phase to avoid tachionic instabilities and anomalies in the specific heat; the blue colored condensate is modeled as a Bardeen-Cooper-Schrieffer (BCS)-type color superconductor. We find that massive stars containing quark matter cool faster in the neutrino-cooling era if one of the colors (blue) is unpaired and/or the remaining colors (red-green) are paired in a inhomogeneous gapless superconducting state. The cooling curves show significant variations along the sequence, as the mass (or the central density) of the models is varied. This feature provides a handle for fine-tuning the models to fit the data on the surface temperatures of same-age neutron stars. In the late-time photon cooling era we observe inversion in the temperature arrangement of models, i.e., stars experiencing fast neutrino cooling are asymptotically hotter than their slowly cooling counterparts.
description: v1: 10 pages, 3 figures; v2: 11 pages 5 figures, matches published version
Additional file 1: of Human iPSC-MSCs prevent steroid-resistant neutrophilic airway inflammation via modulating Th17 phenotypes
Creators: name: Fang, Shu-Bin
name: Zhang, Hong-Yu
name: Jiang, Ai-Yun
name: Fan, Xing-Liang
name: Lin, Yong-Dong
name: Li, Cheng-Lin
name: Wang, Cong
name: Meng, Xiang-Ci
name: Fu, Qing-Ling
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Figure S1. Human iPSC-MSCs showed no effects on murine steroid-resistant airway inflammation at 4 h post-challenge. (A) Representative H&E staining of lung tissues with different treatment (× 200). (B) Representative Diff-Quik staining for the inflammatory cells present in BALF with different treatment (× 200). (C) Statistical analysis of inflammatory scores for the mice that were sacrificed. No significant decreases could be observed in the mice that were treated with DEX or iPSC-MSCs. (D) Statistical analysis of cell counts for the infiltrated inflammatory cells in BALF. Neither DEX nor iPSC-MSCs could reduce the infiltration of inflammatory cells in BALF. *P < 0.05 by the Mann-Whitney U test. Abbreviations: BALF bronchoalveolar lavage fluids, DEX dexamethasone, iPSC-MSCs induced pluripotent stem cell-derived mesenchymal stem cells, ns not significant, PBS phosphate-buffered saline, OVA ovalbumin. n = 5 for PBS/PBS/PBS and OVA/OVA/PBS, n = 6 for OVA/OVA/DEX and OVA/OVA/MSC. Figure S2. Human iPSC-MSCs had no effects on the Th17 level at 48 h post-challenge in a mouse model of steroid-resistant airway inflammation. (A) Representative dot plots showing the percentages of Th1/Th2/Th17 cells in CD4+ T cells at 48 h post-challenge in murine lung tissues. (B) Statistical analysis of T helper cell percentages in lung CD4+ T cells at 48 h post-challenge. No significant changes of the T helper cells could be observed at 48 h post-challenge. Abbreviations: DEX dexamethasone, iPSC-MSCs induced pluripotent stem cell-derived mesenchymal stem cells, ns not significant, PBS phosphate-buffered solution, OVA ovalbumin. n = 6 for OVA/OVA/MSC, n = 5 for the other groups. (DOCX 972 kb)
LA NOZIONE DI DATORE DI LAVORO PUBBLICO NELLA SICUREZZA DEL LAVORO.
Creators: name: LA PORTA, CLEMENTE DAVIDE
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: The research deals with the notion of public employer in the field of health and safety in the workplace, currently regulated by Article 2 (1)(b), Legislative Decree No. 81/2008. Firstly, the research considers the evolution of the discipline from an historical point of view, highlighting both the effects and the main issues concerning its application in the Public Sector. Secondly, it takes into account the notion of public employer in the light of the privatization process that involved the public employment, making a comparison between the latter and the private one. In conclusion, the research investigates the unsolved profiles concerning the definition of public employer provided by the so-called Testo Unico of Health and Safety at the Workplace, questioning the opportunity/necessity to use different notions in relation with the figure of the employer in both the private and the public sectors.
Report on the performance of AtlantOS observing system
Creators: name: Ketelhake, Sandra
name: Visbeck, Martin
name: Belbeoch, Mathieu
name: Cusack, Caroline
name: Ebeler, Laura
name: Fernandez, Vicente
name: Fischer, Albert
name: Fritz, Jan-Stefan
name: Janssen, Felix
name: Gonzalez-Quiros, Rafael
name: Karstensen, Johannes
name: Traon, Pierre-Yves Le
name: Novellino, Antonio
name: Ott, Michael
name: Pouliquen, Sylvie
name: Reilly, Kieran
name: Tanhua, Toste
name: Waldmann, Christoph
Publisher: name: AtlantOS
Year: 2019

description: A report providing an assessment of the adequacy of the cur-rent observing and information system (with results from five pilot countries) will be determined and properly documented. Key findings, experiences and recommendations will be for-mulated to evolve the Integrated Atlantic Ocean Observing System (AtlantOS).
The prognostic impact of the stroke unit care versus conventional care in treatment of patients with transient ischemic attack: a prospective population-based German study
Creators: name: Zeenat Qureshi Stroke Institutes
Publisher: name: Zenodo
Year: 2023

description: Background and purpose: The risk of a stroke after a transient ischemic attack (TIA) is high in the short time following a TIA. The German Stroke Society recommends an early hospitalization of patients with TIA preferably in a stroke unit (SU). This study aims to compare the impact of SU care with conventional care (CC) in patients with TIA. Methods: In a prospective study, during a 36-month phase (starting November 2007), patients with TIA who were admitted to the hospital within 48 h of symptom onset were enrolled. Stroke rate during hospitalization and the 90-day rates of stroke and mortality were studied. Logistic regression analyses were used to estimate the odds ratio (OR). Results: Of 2,200 patients (mean age, 17.6 ± 12 years, 49% female), 1,347 (61%) treated in a SU and 853 (39%) received CC at general departments. Patients treated in SU were significantly younger than those received a CC (69.9 vs. 71.7 years; P = 0.001). TIA patients treated on SU received more ultrasound investigations of the neck arteries (98 vs. 96%; P = 0.003) and of the brain arteries (97 vs. 82%; P < 0.001) than those of CC. The primary outcomes (stroke during hospitalization, stroke after 90 days, and mortality after 90 days) did not show a difference between the SU and CC groups. In patients of male sex, the 90-day stroke rate was significantly lower in the SU group than the CC group (1.8 vs. 4.5%; P = 0.033). Using the adjusted logistic regression analysis, treatment in a SU revealed a reduction of 90-day stroke rate in patients of male sex (OR 0.38; 95% CI 0.15–0.95; P = 0.04). Conclusion: The impact of evaluation and treatment of patients with TIA in SU and CC appears to differ only among patients of male sex. Further randomized trials are necessary
SCIENTIFIC OBSERVATORY MAGAZINE - issn 2965-0704
Creators: name: ACCREDITATION: INTERNATIONAL EDUCATION ASSOCIATION  08-675
Publisher: name: Zenodo
Year: 2023
Subjects: artigos,
ciência
produção cientifica

description: Revista do Centro de Pesquisa Minha Bolsa com artigos dos seus alunos de Mestrado, Doutorado e Pós-Doutorado
Disordered Topological Insulators: A Non-Commutative Geometry Perspective
Creators: name: Prodan, Emil
Publisher: name: arXiv
Year: 2010
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: This review deals with strongly disordered topological insulators and covers some recent applications of a well established analytic theory based on the methods of Non-Commutative Geometry (NCG) and developed for the Integer Quantum Hall-Effect. Our main goal is to exemplify how this theory can be used to define topological invariants in the presence of strong disorder, other than the Chern number, and to discuss the physical properties protected by these invariants. Working with two explicit 2-dimensional models, one for a Chern insulator and one for a Quantum spin-Hall insulator, we first give an in-depth account of the key bulk properties of these topological insulators in the clean and disordered regimes. Extensive numerical simulations are employed here. A brisk but self-contained presentation of the non-commutative theory of the Chern number is given and a novel numerical technique to evaluate the non-commutative Chern number is presented. The non-commutative spin-Chern number is defined and the analytic theory together with the explicit calculation of the topological invariants in the presence of strong disorder are used to explain the key bulk properties seen in the numerical experiments presented in the first part of the review.
description: Topical Review for J. Phys. A
Additional file 1 of Analgesic effect of erector spinae plane block in adults undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized controlled trials
Creators: name: Yang, Xiaoli
name: Zhang, Yu
name: Chen, Yong
name: Xu, Mingxing
name: Lei, Xue
name: Fu, Qiang
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mental Health

description: Additional file 1. Search strategy.
Explainable diagnosis using deep-learning : classification of fundus images as a promising tool for early detection of Alzheimer's disease
Creators: name: Delavari, Parsa
Publisher: name: University of British Columbia
Year: 2022

description: It has recently been shown that Alzheimer’s Disease (AD) can be detected using machine learning methods and based on retinal fundus images, which are readily available in contrast to conventional diagnosis methods, which are highly invasive and expensive. This study aims to design and validate a methodology for explainable diagnosis of AD based on fundus images using deep learning. Because of the rarity of positive AD labels in the available fundus datasets, patient’s sex was alternatively used as a case study since this trait is also invisible to the experts while convolutional neural networks (CNNs) can predict it. This thesis proposes a novel three-phased methodology to investigate the features in retinal fundus images that enable the CNNs to classify sex. In the first phase, a CNN model is trained and tested on the sex classification task using ODIR and DOVS datasets with 3,146 and 1,600 normal images, respectively. In the next phase, deep learning interpretation techniques were used to hypothesize possible sex differences in the retina. In the third and last phase, the hypotheses were tested using an independent dataset called VCH comprising 500 healthy fundus images. The model achieved AUC scores of 0.68 (95% CI: [0.63, 0.72]) and 0.78 (95% CI: [0.73, 0.84]) on ODIR and DOVS test sets respectively. CNN interpretation results demonstrated that the optic disc, retinal vessels, and fovea are the main anatomical parts attended by the model to predict sex. Feature visualization results followed by statistical tests showed that males have more prominent retinal vasculature by showing more nodes (p=.014), more branches (p=.016), and a greater total length of branches (p=.020) in the retinal vessel network as well as a higher superior temporal vessel coverage (p=.027). Also, the peripapillary area was darker in males compared to females (p=.008). The results confirm the capability of the proposed methodology in identifying the retinal features that are relevant to the task on which the CNN model is trained. The same approach can be extended to other clinically important areas, such as AD diagnosis, considering the ability of CNNs to detect this label.
Models of Freight Loss and Damage
Creators: name: Wilson, Lawrence B.
name: Roberts, Paul O.
name: Kneafsey, James T.
name: Wilson, Lawrence B.
name: Roberts, Paul O.
name: Kneafsey, James T.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA
Mathematical inequalities for some divergences
Creators: name: Furuichi, S.
name: Mitroi, F. -C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Information Theory (cs.IT)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 94A17, 26D15

description: Divergences often play important roles for study in information science so that it is indispensable to investigate their fundamental properties. There is also a mathematical significance of such results. In this paper, we introduce some parametric extended divergences combining Jeffreys divergence and Tsallis entropy defined by generalized logarithmic functions, which lead to new inequalities. In addition, we give lower bounds for one-parameter extended Fermi-Dirac and Bose-Einstein divergences. Finally, we establish some inequalities for the Tsallis entropy, the Tsallis relative entropy and some divergences by the use of the Young's inequality.
description: 18 pages
Lattice generalization of the Dirac equation to general spin and the role of the flat band
Creators: name: Dóra, Balázs
name: Kailasvuori, Janik
name: Moessner, Roderich
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We provide a novel setup for generalizing the two-dimensional pseudospin S=1/2 Dirac equation, arising in graphene's honeycomb lattice, to general pseudospin-S. We engineer these band structures as a nearest-neighbor hopping Hamiltonian involving stacked triangular lattices. We obtain multi-layered low energy excitations around half-filling described by a two-dimensional Dirac equation of the form H=v_F S\cdot p, where S represents an arbitrary spin-S (integer or half-integer). For integer-S, a flat band appears, whose presence modifies qualitatively the response of the system. Among physical observables, the density of states, the optical conductivity and the peculiarities of Klein tunneling are investigated. We also study Chern numbers as well as the zero-energy Landau level degeneracy. By changing the stacking pattern, the topological properties are altered significantly, with no obvious analogue in multilayer graphene stacks.
description: 14 pages, 6 figures, 1 table, revised version with a new section on experimental possibilities
КЛИНИЧЕСКАЯ КАРТИНА ИШЕМИЧЕСКОГО ИНСУЛЬТА В СОЧЕТАНИИ С ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА
Creators: name: Ходжаева, Назира
Publisher: name: Zenodo
Year: 2023

description: При исследовании особенностей  клинической картины ишемического инсульта в зависимости от наличия сердечной патологии у 182 пациента (95 женщин и 87 мужчин) в возрасте от 41 до 79 лет в острейшем и остром периодах ишемического инсульта (ИИ) в бассейне средней мозговой артерии (СМА), было выявлено, что общемозговая и очаговая симптоматика инсульта была более выраженной, а общее состояние чаще было тяжелым у пациентов с ИБС, особенно у лиц женского пола.
Caveolin-1 mediates mitochondrial potential and ROS through ROCK/AMPK regulation of mitophagy
Creators: name: Timmins, Logan Rayne
Publisher: name: University of British Columbia
Year: 2022

description: Cancer cells often exhibit altered metabolisms that support aerobic glycolysis and reduced mitochondrial function to promote cell survival. Caveolin-1 (Cav1) is an integral membrane protein and the main structural component of caveolae. Caveolae formation requires the adaptor protein Cavin1 and without it, Cav1 forms scaffolds at the plasma membrane. Cav1 can be phosphorylated at tyrosine-14 (pCav1) and is involved in signal transduction, cell migration, and mitochondrial function. Cav1 plays contrasting roles in cancer progression and its precise role in metabolism and, specifically, mitochondrial function remains poorly defined. Using a potential- dependent mitochondrial reporter, MitoView 633, and a mitochondrial reactive oxygen species (ROS) reporter, MitoSOX Red, we report that CRISPR/Cas9 knockout of Cav1 in MDA-MB- 231 triple-negative breast cancer cells increases mitochondrial potential and reduces ROS. These effects are reversed upon reintroduction of Cav1 by stably expressing Cav1 in KO cells. Further, introduction of the Cav1 Y14D phosphomimetic mutant decreased mitochondrial potential in Cav1 KO cells while the Y14F non-phosphorylatable mutant did not. pCav1 is a known effector of Rho-associated kinase (ROCK) signaling. Treatment of MDA-MB-231 cells with Y-27632, a ROCK1/2 inhibitor, or with ROCK1/2 siRNA increased mitochondrial potential and decreased ROS in Cav1-expressing cells. Similar results were observed in PC3 prostate cancer cells that lack caveolae suggesting this is a caveolae-independent effect. Use of the mito-Keima mitophagy probe reported increased basal mitophagy in Cav1 KO MDA-MB-231 and PC3 cells and induction of mitophagy by ROCK inhibition in Cav1-expressing cells. Knockdown of the autophagy protein ATG5 and mitophagy regulator PINK1 in Cav1 KO MDA-MB-231 cells reduced potential and increased ROS while Cav1-expressing cells were not significantly affected, demonstrating that mitophagy promotes mitochondrial health and reduces ROS in Cav1 KO cells. Finally, we show that Cav1 KO MDA-MB-231 cells have more active AMP-activated protein kinase (AMPK), a major mitochondrial homeostasis protein whose activity is inhibited by ROCK. Knockdown of AMPK resulted in decreased mitochondrial potential, increased ROS, and decreased mitophagy in Cav1 KO cells while the Cav1-expressing cells were not affected. Overall, our results suggest that Cav1 expression in cancer cells reduces mitochondrial potential and increases ROS via ROCK/AMPK regulated mitophagy.
Impact of Branch-Line Rail Abandonment on Costs and Structure of Fertilizer Distribution
Creators: name: Berglund, Mary
name: Anderson, Dale G.
name: Berglund, Mary
name: Anderson, Dale G.
Publisher: name: Unknown
Year: 1977
Subjects: Public Economics

description: Presented at the 18th Transportation Research Forum meeting, Oct. 17-19, 1977, Atlanta, GA