cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The validity of technology-based dietary assessment methods in childhood and adolescence: a systematic review
Creators: name: Kouvari, Matina
name: Mamalaki, Eirini
name: Bathrellou, Eirini
name: Poulimeneas, Dimitrios
name: Yannakoulia, Mary
name: Demosthenes B. Panagiotakos
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Technology-based dietary assessment has promising benefits on improving accuracy and reducing cost of dietary data collection. The validity of technology-based tools in children/adolescents was examined. A systematic literature search was performed to identify studies published till September 2019. In total, 26 studies with 29 validation-related estimations were selected; 13 web-based 24-hdietary recalls (image assisted; n = 12, drop-down food list; n = 13), 4 mobile applications and 3 web-based dietary records (image based; n = 2 and image assisted; n = 1, drop-down food list; n = 3) and 6 web-based food frequency questionnaires (FFQs) (image assisted; n = 3). Fourteen studies were addressed to adolescents, ten studies to children (principally 9–11 years old) and two studies to mixed study samples. Validation was mostly performed through 24-h dietary recalls and dietary records while in some cases objective methods were used. Image-assisted 24-h dietary recalls presented good level of agreement with paper-based methods, yet principally in adolescents. Mobile-application dietary records with image-based facilities and drop-down food lists were found to accurately record dietary intake even when compared with objective methods. FFQs, mainly examined in adolescents, had good level of agreement with the “gold standard” dietary records method. The validity of technology-based methods could be supported yet various technical/methodological issues need better clarification.
Additional file 9 of Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans
Creators: name: J. Alexander-Floyd
name: S. Haroon
name: M. Ying
name: A. Entezari
name: C. Jaeger
name: M. Vermulst
name: T. Gidalevitz
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 9: Data File 1. List of genes in the drxIR1 interval with potentially significant SNPs generated by the SnpEff tool. The nucleotide positions correspond to the N2(Bristol) genome assembly from WormBase release WS220 [131], available in the UCSC Genome Browser as ce10. The presence of human orthologs is according to [132].
A Verified Packrat Parser Interpreter for Parsing Expression Grammars
Creators: name: Blaudeau, Clement
name: Shankar, Natarajan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: Parsing expression grammars (PEGs) offer a natural opportunity for building verified parser interpreters based on higher-order parsing combinators. PEGs are expressive, unambiguous, and efficient to parse in a top-down recursive descent style. We use the rich type system of the PVS specification language and verification system to formalize the metatheory of PEGs and define a reference implementation of a recursive parser interpreter for PEGs. In order to ensure termination of parsing, we define a notion of a well-formed grammar. Rather than relying on an inductive definition of parsing, we use abstract syntax trees that represent the computational trace of the parser to provide an effective proof certificate for correct parsing and ensure that parsing properties including soundness and completeness are maintained. The correctness properties are embedded in the types of the operations so that the proofs can be easily constructed from local proof obligations. Building on the reference parser interpreter, we define a packrat parser interpreter as well as an extension that is capable of semantic interpretation. Both these parser interpreters are proved equivalent to the reference one. All of the parsers are executable. The proofs are formalized in mathematical terms so that similar parser interpreters can be defined in any specification language with a type system similar to PVS.
description: 15 pages, 15 figures, Certified Proofs and Programs
Additional file 1 of Lung endothelial cells are sensitive to epsilon toxin from Clostridium perfringens
Creators: name: Jonatan Dorca-Arévalo
name: Dorca, Eduard
name: Torrejón-Escribano, Benjamín
name: Blanch, Marta
name: Martín-Satué, Mireia
name: Blasi, Juan
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. GFP-pEtx, but not GFP alone, binds to 1G11 mouse endothelial cells. Confocal microscopy images show the binding of GFP-pEtx but not GFP alone, to the plasma membrane of 1G11 cells. The cells were incubated with GFP-pEtx (A–C) or GFP alone (D–F), and the nuclei were stained with TO-PRO3 (Blue, B, C, E and F). Note GFP-pEtx binding to the plasma membrane of 1G11 cells (green, in A and arrows in C) which was not detected in incubations with GFP alone (D and F). Scale bar 25 µm.
Additional file 7 of Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans
Creators: name: J. Alexander-Floyd
name: S. Haroon
name: M. Ying
name: A. Entezari
name: C. Jaeger
name: M. Vermulst
name: T. Gidalevitz
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Additional file 7: Table S3. Primers used for genotyping the drxIR1 locus and for qPCR analysis of atg-5 expression.
Deriving predicted no-effect concentrations (PNECs) using a novel assessment factor method
Creators: name: Okonski, Alexander I.
name: MacDonald, Drew B.
name: Potter, Kelly
name: Bonnell, Mark
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Ecological risk assessments of substances with limited ecotoxicity datasets typically employ an assessment factor (AF) method to determine a predicted no-effect concentration (PNEC) needed for risk characterization. A PNEC is usually derived by dividing the lowest toxicity value in the substance’s dataset by a certain assessment factor. The AF method, in its various iterations, has been used for decades, and has been criticized for its uncertainty, inaccuracy, over-conservatism, high variability, and lack of transparency. A novel assessment factor method is proposed as an alternative to traditional AF methods. The proposed method offers novel features attempting to address these criticisms: it breaks the factor down into three components - endpoint standardization, extrapolation for species variation, and mode-of-action consideration (each of which has sub-components). This method also accommodates the inclusion of read-across and modeled data to fill data gaps for the substance. In addition, it better manages atypical datasets and atypical endpoints. Finally, and paramount to this endeavor, this novel method improves consistency among risk assessors, and can increase transparency of the entire PNEC derivation process to all stakeholders.
A Joint Mid-Infrared Spectroscopic and X-Ray Imaging Investigation of Liner Galaxies
Creators: name: Satyapal, S.
name: Sambruna, R. M.
name: Dudik, R. P.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a comprehensive comparative high resolution mid-IR spectroscopic and X-ray imaging investigation of LINERs using archival observations from the ISO-SWS and the Chandra Advanced CCD Imaging Spectrometer. Although the sample is heterogenous and incomplete, this is the first comprehensive study of the mid-infrared fine structure line emission of LINERs. These results have been compared with similar observations of starburst galaxies and AGN. We find that LINERs very clearly fall between starbursts and AGN in their mid-IR fine structure line spectra, showing L_[OIV]26um/L_FIR and L_[OIV]26um/L_[NeII]12.8um ratios, both measures of the dominant nuclear energy source in dust-enshrouded galaxies, intermediate between those of AGN and starbursts. Chandra imaging observations of the LINERs reveal hard nuclear point sources morphologically consistent with AGN in most (67%) of the sample, with a clear trend with IR-brightness. Most LINERs that show a single dominant hard compact X-ray core are IR-faint ((L_FIR/L_B < 1), whereas most LINERs that show scattered X-ray sources are IR-bright. A comparative X-ray/mid-IR spectroscopic investigation of LINERs reveals some puzzling results. Objects that display strong hard nuclear X-ray cores should also display high excitation lines in the IR. However, we find two LINERs disagree with this expectation. The galaxy NGC 404 shows weak soft X-ray emission consistent with a starburst but has the most prominent highest excitation mid-IR spectrum of our entire sample. Using IR emission line diagnostics alone, this galaxy would be classified as hosting a dominant AGN. Conversely, the IR luminous LINER NGC 6240 has an extremely luminous binary AGN as revealed by the X-rays but shows weak IR emission lines.
description: 17 pages, 12 figures, accepted for publication in A&A
The (in)complete landscape of breast cancer in Pakistan
Creators: name: Jahan, Zainab
name: Riaz, Arsalan
name: Rustam, Zainab
name: Khan, Faisal
Publisher: name: Zenodo
Year: 2023

description: Breast cancer is the most common cancer among women in the world, with incidence rising every year. In 2020, according to GLOBOCAN, Pakistan had 25,928 breast cancer cases, estimated using data from India. In order to obtain comprehensive insights into the epidemiology, risk factors, and disease burden of breast cancer in Pakistan [1, 2], we embarked on this systematic review. We aim to bridge the data gap and provide clinicians and policymakers with a reliable and comprehensive snapshot of breast cancer in Pakistan.
Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)]4 by anticancer drug adriamycin
Creators: name: Barthwal, Ritu
name: Shailja Raje
name: Pandav, Kumud
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: Besides inhibiting DNA duplication, DNA dependent RNA synthesis and topoisomerase-II enzyme action, anticancer drug adriamycin is found to cause telomere dysfunction and shows multiple strategies of action on gene functioning. We present evidence of binding of adriamycin to parallel stranded intermolecular [d-(TTAGGGT)]4 G-quadruplex DNA comprising human telomeric DNA by proton and phosphorus-31 nuclear magnetic resonance spectroscopy. Diffusion ordered spectroscopy shows formation of complex between the two molecules. Changes in chemical shift and line broadening of DNA and adriamycin protons suggest participation of specific chemical groups/moieties in interaction. Presence of sequential nuclear Overhauser enhancements at all base quartet steps and absence of large downfield shifts in 31P resonances give clear proof of absence of intercalation of adriamycin chromophore between base quartets. Restrained molecular dynamics simulations using observed 15 short intermolecular inter proton distance contacts depict stacking of ring D of adriamycin with terminal G6 quartet by displacing T7 base and external groove binding close to T1-T2-A3 bases. The disappearance of imino protons monitored as a function of temperature and differential scanning calorimetry experiments yield thermal stabilization of 24 °C, which is likely to come in the way of telomerase association with telomeres. The findings pave the way for design of alternate anthracycline based drugs with specific modifications at ring D to enhance induced thermal stabilization and use alternate mechanism of binding to G-quadruplex DNA for interference in functional pathway of telomere maintenance by telomerase enzyme besides their well known action on duplex DNA.
Invariant-based inverse engineering for fast and robust load transport in a double pendulum bridge crane
Creators: name: Lizuain, I.
name: Tobalina, A.
name: Rodriguez-Prieto, A.
name: Muga, J. G.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Classical Physics (physics.class-ph)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: We set a shortcut-to-adiabaticity strategy to design the trolley motion in a double-pendulum bridge crane. The trajectories found guarantee payload transport without residual excitation regardless of the initial conditions within the small oscillations regime. The results are compared with exact dynamics to set the working domain of the approach. The method is free from instabilities due boundary effects or to resonances with the two natural frequencies.
description: 9 pages, 6 figures
The stigma impact of Non-GMO label on conventional unlabeled alcohol products
Creators: name: Li, Jie
name: Ma, Zekun
name: Gomez, Miguel I.
name: Yeh, D. Adeline
name: Ge, Frank
name: Li, Jie
name: Ma, Zekun
name: Gomez, Miguel I.
name: Yeh, D. Adeline
name: Ge, Frank
Publisher: name: Unknown
Year: 2019
Subjects: subject: Marketing
subject: FOS: Economics and business

description: Presentation ID 16436
Rotating tensor-multi-scalar solitons
Creators: name: Collodel, Lucas G.
name: Doneva, Daniela D.
name: Yazadjiev, Stoytcho S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In the context of a special class of tensor-multi-scalar theories of gravity for which the target-space metric admits an isometry under which the theory is invariant, we present rotating vacuum solutions, namely with no matter fields. These objects behave like nontopological solitons, whose primary stability is due to the conserved charge arising from the global symmetry. We consider theories with two and three scalar fields, different Gauss curvatures and quartic interaction coefficients. As it occurs for boson stars, their angular momentum is quantized.
title: Lettres de Jacques Leibowitch à Luc Montagnier
Creators: name: Leibowitch, Jacques
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/Calames-20193111133351228
description: created: start=1993-10-13;end=1994-06-30
On The Existence of Roton Excitations in Bose Einstein Condensates: Signature of Proximity to a Mott Insulating Phase
Creators: name: Nazario, Zaira
name: Santiago, David I.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Within the last decade, artificially engineered Bose Einstein Condensation has been achieved in atomic systems. Bose Einstein Condensates are superfluids just like bosonic Helium is and all interacting bosonic fluids are expected to be at low enough temperatures. One difference between the two systems is that superfluid Helium exhibits roton excitations while Bose Einstein Condensates have never been observed to have such excitations. The reason for the roton minimum in Helium is its proximity to a solid phase. The roton minimum is a consequence of enhanced density fluctuations at the reciprocal lattice vector of the stillborn solid. Bose Einstein Condensates in atomic traps are not near a solid phase and therefore do not exhibit roton minimum. We conclude that if Bose Einstein Condensates in an optical lattice are tuned near a transition to a Mott insulating phase, a roton minimum will develop at a reciprocal lattice vector of the lattice. Equivalently, a peak in the structure factor will appear at such a wavevector. The smallness of the roton gap or the largeness of the structure factor peak are experimental signatures of the proximity to the Mott transition.
description: 4 pages, 5 figures
Hydration thermodynamics of cytosolic phospholipase A2 IVA predict its membrane-associated parts and its highly hydrated binding site
Creators: name: Vasilakaki, Sofia
name: Kraml, Johannes
name: Schauperl, Michael
name: Liedl, Klaus R.
name: Kokotos, George
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: During biological events, the water molecules associated with the protein are re-oriented to adapt to the new conditions, inducing changes in the system’s free energy. The characterization of water structure and thermodynamics may facilitate the prediction of certain biological events, such as the binding of a ligand and the membrane-associated parts of a protein. In this computational study, we calculated the hydration thermodynamics of cytosolic phospholipase A2 group IV (GIVA cPLA2) to study the hydration properties of the protein’s surface and binding pocket. Hydrophobicity scales and the Grid Inhomogeneous Solvation Theory (GIST) tool were employed for the calculations. The hydrophobic areas of the protein’s surface were predicted more accurately with the GIST method rather than with the hydrophobicity scales. Based on this, a model of the protein-membrane complex was constructed. In addition, the calculation revealed the highly hydrated binding pocket that further contribute to our understanding of the ligands’ binding.
Probabilistic cancer risk assessment for dietary intake of seven nitrosamine chemicals in Korea
Creators: name: Jae-Woong Jung
name: Un-Jung Kim
name: Wook-Joon Yu
name: June-Woo Park
name: Jeong, Eun Ju
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy

description: We conducted a probabilistic risk assessment for seven nitrosamines (i.e., N-nitrosodimethylamine (NDMA), N-nitrosodiethylamine (NDEA), N-nitrosodibuthylmine (NDBA), N-nitrosopyrrolidine (NPYR), N-nitrosopiperidine (NPIP), N-nitrosomorpholone (NMOR) and N-nitrosomethylethylamine (NMEA)) to assess the cancer risk posed by dietary intake of nitrosamines for Korean people. The estimated cancer risks were the highest in the order of NDMA, NDEA, NDBA, NPYR, NPIP, NMOR and NMEA. The cancer risks of NPYR, NPIP, NMOR and NMEA was estimated to be lower than de minimis risk (i.e., a cancer risk of 10−6), and thus, can be ignored. The derived cancer risks of NDEA and NDBA exceeded de minimis risk, but did not exceed de manifestis risk (i.e., a cancer risk of 10−4), meaning that no imminent action is required for either chemical. However, because the high-end cancer risk (i.e., > 90th percentile) by NDMA intake exceeded de manifestis risk owing to its strong carcinogenicity and high daily intake rate, action to reduce the cancer risk from dietary intake of NDMA is strongly warranted. Because NDMA formation in foods is an unavoidable chemical reaction between NDMA precursors (i.e., nitrogen oxides and organic amines), we recommend focusing on reducing the contents of NDMA precursors in foods as a best management practice.
Additional file 6 of Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans
Creators: name: J. Alexander-Floyd
name: S. Haroon
name: M. Ying
name: A. Entezari
name: C. Jaeger
name: M. Vermulst
name: T. Gidalevitz
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 6: Table S2. Candidate genes tested by RNAi. 24 candidate genes present in the target 326 Kb of drxIR1 interval (between SNPs 5 and 6b (Additional file 1: Fig. S1)) are indicated in color. Genes were defined as candidates based on the SnpEff annotations (see Methods and Additional file: Data File 1). egl-30 was excluded based on genetic crosses. Genes in purple were targeted by clones from the Ahringer RNAi library. RNAi targeting constructs for genes in red were prepared in this work.
The influence of wine awards and sustainability labels on consumers’ WTP: An experimental study at the example of German “Riesling”
Creators: name: Klink-Lehmann, Jeanette Leila
name: Yeh, Ching-Hua
name: Hartmann, Monika
name: Klink-Lehmann, Jeanette Leila
name: Yeh, Ching-Hua
name: Hartmann, Monika
Publisher: name: Unknown
Year: 2019
Subjects: subject: Marketing
subject: FOS: Economics and business

description: Presentation ID 16665
Adjacent dimer epitope of envelope protein as an important region for Zika virus serum neutralization: a computational investigation
Creators: name: Fuzo, Carlos Alessandro
name: Luiz Felipe Lemes De Araujo
name: De Souza Pontes, Rafael
name: Évora, Patricia Martinez
name: Stabeli, Rodrigo Guerino
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The recent emergence of Zika virus (ZIKV) has affected many countries, with severe clinical manifestations such as fetal microcephaly and Guillain-Barré syndrome. However, even though it is a major public health concern, there is no approved treatment available. Structural knowledge of the main neutralization regions of the envelope (E) protein of ZIKV and its interactions with neutralizing antibodies (nAbs) are crucial for the rational development of subunit vaccines and establishment of antibody-based interventions. In this study we screened from public data hot spot epitopes in conserved regions of ZIKV E protein that are nAbs targets. The result points to a conserved epitope located at domain II of the ZIKV E protein, namely adjacent dimer epitope, which is the ZIKV-117 and Z20 nAbs target. Although these two nAbs have been isolated from different donors, we have demonstrated, from structural and energetic details obtained by molecular dynamics of native and mutants, that hot spots residues of the epitope are the same for these nAbs, thereby indicating that they may share similar binding and neutralization mechanism. This convergence of information between these nAbs is important because both are potential targets for the development of therapies against ZIKV and only Z20 has its sequence and its complex structure with ZIKV E protein determined. Finally, these findings also contribute to existing knowledge, by fine mapping of the epitope/paratope residue pairs that are important for biotechnological development of therapies such as epitope mimetics for subunit vaccines and the rational design for antibody-based interventions against ZIKV. Communicated by Ramaswamy H. Sarma
A Hedonic Price Analysis of Processed Food Attributes in Tanzania
Creators: name: Snyder, Jason E.
name: Tschirley, David L.
name: Reardon, Thomas A.
name: Ross, Brent R.
name: Snyder, Jason E.
name: Tschirley, David L.
name: Reardon, Thomas A.
name: Ross, Brent R.
Publisher: name: Unknown
Year: 2019
Subjects: subject: Marketing
subject: FOS: Economics and business

description: Presentation ID 16770
Modeling pesticide use intention in Pakistani farmers using expanded versions of the theory of planned behavior
Creators: name: Khan, Fawad Zafar Ahmad
name: Manzoor, Syed Amir
name: Akmal, Muhammad
name: Imran, Muhammad Usama
name: Taqi, Muhammad
name: Manzoor, Syed Asad
name: Lukac, Martin
name: Gul, Hafiza Tahira
name: Shimat V. Joseph
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: We explore the intentions of farmers’ pesticide use by using expanded versions of the theory of planned behavior (TPB). We added variables such as farmers’ knowledge about pesticides, moral norms, progressive farming approach, farm size, farming experience, and formal education of the farmers as additional predictors in the original TPB model. We interviewed 390 cotton farmers in Multan and used a hierarchical multiple regression modeling framework to run a series of multiple regression models (based on original and expanded versions of TPB) and found that the expanded TPB models with the addition of, (a) farmers’ knowledge of pesticides (R2 change = 0.089, F change(2, 384) = 24.8, p 2 change = 0.037, F change(1, 383) = 21.5, p 2 change = 0.032, F change(3, 380) = 6.4, p t = 6.320, p < 0.01), and progressive farming approach (β = 2.80, t = 5.834, p
Η δημιουργική λέξη και η ένθεη πράξη: Γλώσσα, λογοτεχνία και νεωτερική εμπειρία στον στοχασμό του Walter Benjamin
Creators: name: Κοκκίνης, Γεώργιος Απόστολου
Publisher: name: Aristotle University of Thessaloniki
Year: 2021
Subjects: subject: Φιλοσοφία
subject: Γλώσσα
subject: Βάλτερ Μπένγιαμιν
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Language
subject: Walter Benjamin

description: Ο Walter Benjamin (1892-1940) υπήρξε ένας από τους πλέον διορατικούς εκφραστές της ανθρώπινης εμπειρίας κατά την ταραγμένη περίοδο της νεωτερικότητας. Η πολυσχιδής συγγραφική του συγκομιδή, η ενασχόλησή του με τη γλώσσα και την τέχνη, την ιστορία και τις τεχνολογικές εξελίξεις ανήκουν, αναμφίβολα, στις διαυγέστερες απόπειρες ψηλάφησης του ατομικού και κοινωνικού βιώματος μέχρι τις μέρες μας. Η παρούσα εργασία στρέφεται κυρίως στην ιδιότυπη γλωσσοφιλοσοφία του στοχαστή, καθώς και στην εκ μέρους του πρόσληψη ενός αριθμού σημαντικών λογοτεχνικών έργων του 19ου και 20ου αιώνα. Καταφάσκοντας –στον βαθμό που μας επιτρέπεται στα πλαίσια μιας ακαδημαϊκής εργασίας– στις μεθοδολογικές προτροπές του Benjamin, θα επιχειρήσουμε να ακολουθήσουμε τις σκέψεις του ίδιου σχετικά με τη μαγεία της γλώσσας, την οντολογική διάσταση της μεταφραστικής πρακτικής, αλλά και το διανοητικό εκτόπισμα συγγραφέων όπως ο Kafka, ο Leskov και ο Baudelaire.
description: Walter Benjamin (1892-1940) was one of the most insightful exponents of human experience during the turbulent period of modernity. His diverse writings, his preoccupation with language and art, history and technological developments belong, undoubtedly, to the clearest attempts at grasping the individual and social experience even to this day. The present thesis focuses primarily on the original linguistic philosophy of the thinker, as well as on his interpretation of a number of important literary works of the 19th and 20th centuries. Following Benjamin's methodological exhortations –as far as the process of approaching an academic study allows us–, we will try to trace his thoughts on the magic of language, the ontological dimension of translation practice, but also the intellectual output of writers such as Kafka, Leskov and Baudelaire.
A new analogue of islet neogenesis associated protein with higher structural and plasma stability
Creators: name: Lynn, Soledad
name: Yanis Ricardo Espinosa Silva
name: Diambra, Luis
name: McCarthy, Andrés Norman
name: Liping, Liu
name: Ru, Bai
name: Román, Carolina Lisi
name: Maiztegui, Barbara
name: Flores, Luis Emilio
name: Gagliardino, Juan José
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: Islet Neogenesis Associated Protein pentadecapeptide (INGAP-PP) increases β-cell mass and function in experimental animals. A short clinical trial also yielded promising results. However, HTD4010, a new peptide derived from INGAP-PP, was developed in order to optimize its specific effects by minimizing its side effects. To study and compare the tertiary structure, stability dynamics, and plasma stability of HTD4010, an INGAP-PP analogue. Both peptides were pre-incubated in human, rat and mouse plasma at 37 °C, and their presence was identified and quantified by high performance liquid chromatography at different time-points. GROMACS 2019 package and the Gromos 54A7 force field were used to evaluate overall correlated motion of the peptide molecule during molecular dynamics simulation by essential dynamics. HTD4010 exhibited significantly larger plasma stability than INGAP-PP, and its structural stability was almost 3.36-fold higher than INGAP-PP. These results suggest that HTD4010 may facilitate longer tissue interaction, thereby developing higher potential biological effects. If so, HTD4010 may become a promising therapeutic agent to treat people with diabetes. Communicated by Ramaswamy H. Sarma
Additional file 1 of Acute and chronic effects of multivitamin/mineral supplementation on objective and subjective energy measures
Creators: name: F. Dodd
name: D. Kennedy
name: E. Stevenson
name: R. Veasey
name: K. Walker
name: S. Reed
name: P. Jackson
name: C. Haskell-Ramsay
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Indirect calorimetry during exercise. Table S2. Indirect calorimetry during cognitive tasks. Table S3. Tiredness ratings during exercise and cognitive tasks. Table S4. Rating of Perceived Exertion during exercise. Table S5. Energy and stress ratings during cognitive tasks. Table S6. Cognitive task performance. Table S7. Micronutrient, creatinine and homocysteine levels. Table S8. Recovery biomarker levels.
Food citizenship and home economics education : a conceptual analysis
Creators: name: Williams, Sheila Marie
Publisher: name: The University of British Columbia
Year: 2023

description: Our current food system relies heavily upon industrial agriculture and globalization. This has created a disconnect between people and their food sources. Most people are passive consumers when it comes to their food related behaviours and decisions. The concept of food citizenship aims to shape a democratic, socially and economically just, and environmentally sustainable food system while addressing a person’s rights, obligations and responsibilities. Food citizenship allows for empowerment of individuals to analyze and critique how their food is produced and where it comes from. Action can occur at the individual or collective level. The goal of food citizenship is to contribute to the betterment of family, home, community, and society. The purpose of this research paper is to conceptualize food citizenship, argue for its inclusion as an educational goal for home economics, and provide recommendations for implementation in a foods and nutrition course.
Magnetic response and quantum critical behavior in the doped two-leg extended Hubbard ladder
Creators: name: Tsuchiizu, M.
name: Suzumura, Y.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We have investigated quantum critical behavior in the doped two-leg extended Hubbard ladder, by using a weak-coupling bosonization method. In the ground state, the dominant fluctuation changes from the conventional d-wave-like superconducting (SCd) state into density-wave states, with increasing nearest-neighbor repulsions and/or decreasing doping rate. The competition between the SCd state and the charge-density-wave state coexisting with the p-density-wave state becomes noticeable on the critical point, at which the gap for magnetic excitations vanishes. Based on the Majorana-fermion description of the effective theory, we calculate the temperature dependence of the magnetic response such as the spin susceptibility and the NMR relaxation rate, which exhibit unusual properties due to two kinds of spin excitation modes. On the quantum critical point, the spin susceptibility shows paramagnetic behavior with logarithmic corrections and the NMR relaxation rate also exhibits anomalous power-law behavior. We discuss the commensurability effect due to the umklapp scattering and relevance to the two-leg ladder compounds Sr_{14-x}Ca_xCu_{24}O_{41}.
description: 18 pages, 9 figures, accepted for publication in Phys. Rev. B
Differential Price Pass-Through in Organic and Conventional Food Markets
Creators: name: Li, Qingxiao
name: Cakir, Metin
name: Beatty, Timothy
name: Park, Timothy A.
name: Li, Qingxiao
name: Cakir, Metin
name: Beatty, Timothy
name: Park, Timothy A.
Publisher: name: Unknown
Year: 2019
Subjects: subject: Marketing
subject: FOS: Economics and business

description: Presentation ID 15400
Exploring the potency of currently used drugs against HIV-1 protease of subtype D variant by using multiscale simulations
Creators: name: Md Fulbabu Sk
name: Rajarshi Roy
name: Kar, Parimal
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Acquired immune deficiency syndrome (AIDS) is caused by the human immunodeficiency virus (HIV), type 1 and 2. Further, the diversity in HIV-1 has given rise to many serotypes and recombinant strains. The currently used protease inhibitors have been developed for subtype B, although non-B subtype strains account for ∼ 90% of the global HIV infections. Subtype D is spreading rapidly and infecting a large population in North Africa and the Middle East. In the current study, molecular dynamics simulations in conjunction with the molecular mechanics/Poisson-Boltzmann surface area (MM-PBSA) scheme was used to investigate the potency of four drugs, namely atazanavir (ATV), darunavir (DRV), lopinavir (LPV) and tipranavir (TPV) against the subtype D variant. Our calculations predicted that the potency of the inhibitors decreased in the order TPV > ATV > DRV > LPV. TPV was found to be the most potent against subtype D due to an increase in van der Waals and electrostatic interactions and reduction in the desolvation energy compared to other inhibitors. This result is further supported by the hydrogen bond interactions between inhibitors and protease. Furthermore, our analyses suggested that the binding of TPV induced a more closed conformation of the flap compared to apo or other complexes. It was observed that TPV/PRD has a lower cavity volume relative to the other three complexes leading to a tighter binding. The open conformation of the flap was observed for LPV/PRD. We expect that this study might be useful for designing more potent inhibitors against HIV-1 subtype D. Communicated by Ramaswamy H. Sarma
Signaling Impacts of GMO Labeling on Fruit and Vegetable Demand
Creators: name: Yeh, D. Adeline
name: Gomez, Miguel I.
name: Kaiser, Harry M.
name: Yeh, D. Adeline
name: Gomez, Miguel I.
name: Kaiser, Harry M.
Publisher: name: Unknown
Year: 2019
Subjects: subject: Marketing
subject: FOS: Economics and business

description: Presentation ID 15668
Typhlodromips cameroonensis Zannou & Zundel & Hanna & Moraes 2005, sp. nov.
Creators: name: Zannou, Ignace Dossa
name: Zundel, Christine
name: Hanna, Rachid
name: Moraes, Gilberto Jose
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Phytoseiidae
Typhlodromips
Typhlodromips cameroonensis

description: Typhlodromips cameroonensis sp. nov.
 Material Examined
Holotype female and 1 paratype female from an unknown plant, Mankon village, 05°58'26" N x 10°05'46" E, Bamenda, Cameroon, 26 February 2004, altitude 1251 m, coll. C. Zundel, deposited at the International Institute of Tropical Agriculture Insect Museum (IITAIM), Cotonou, Republic of Benin.
 Female (Figs 2A–2D) (2 specimens measured) Dorsum. Dorsal shield smooth, 389 (387–390) long x 207 (205–208) wide at widest level of the proscutum. Setae j1 21 (19–22), j3 34 (32–35), j4 12 (10–13), j5 12 (11–13), j6 12 (11–13), J2 12 (11–13), J5 6, z2 17 (16–18), z4 30 (29–30), z5 11 (10–11), Z1 13, Z4 60 (59–61), Z5 69 (67–70), s4 51, S2 14 (13–14), S4 11, S5 11, r3 21 (19–22), R1 11 (10–11). Setae Z 4 and Z5 slightly serrate; other setae smooth.
 Peritreme. Extending forward to the level of insertion of j1.
 Venter. All shields clearly discernable, sternal and genital shields smooth, ventri­anal shield slightly reticulate. Sternal shield with posterior margin concave, three pairs of setae and two pairs of lyrifissures. Setae St4 on distinct metasternal shields. Distances between setae St1–St3 71 (70–72), St2–St2 74, St5–St5 75 (74–75). Ventri­anal shield sub­quadrate, 120 (112–128) long, 122 (118–125) wide at level of Zv2 and 98 (96–99) wide at level of anus; anterior margin convex; with three pairs of pre­anal setae (Jv1, Jv2, Zv2) and a pair of relatively large pores mesad of Jv2. Soft cuticle surrounding shield with two pairs of metapodal shields and 4 pairs of ventral opisthosomal setae (Jv4, Jv5, Zv1, Zv3).
 Chelicera. Movable digit 35 long, apparently with three teeth; fixed digit 32 long, apparently with seven teeth.
 Spermatheca. Calyx cup­shaped, 15 (14–16) long; atrium distinct.
 Legs. With blunt­tipped macrosetae on all legs, except macroseta on tarsus IV which is sharp­tipped: Sge I 34 (32–35), Sge II 30, Sge III 29, Sti III 29, Sge IV 47 (46–48), Sti IV 32, and St IV 71 (70–72). Chaetotaxy of genu II 2­2/0,2/0­1; genu III 1­2/1,2/0­1.
 Male Unknown.
 Notes
 This species is most similar to T. arbuti (DeLeon 1961), which however has the ventrianal shield distinctly longer than wide, and has much longer macroseta on tarsus IV.
 Etymology
 The epithet cameroonensis refers to the country where the type specimens were collected.
description: Published as part of Zannou, Ignace Dossa, Zundel, Christine, Hanna, Rachid & Moraes, Gilberto Jose, 2005, Two new species of phytoseiid mites (Acari: Phytoseiidae) from Cameroon, Central Africa, pp. 55-59 in Zootaxa 1093 (1) on pages 57-59, DOI: 10.11646/zootaxa.1093.1.5, http://zenodo.org/record/5051308
Variational Problems for Tree Roots and Branches
Creators: name: Bressan, Alberto
name: Palladino, Michele
name: Sun, Qing
Publisher: name: arXiv
Year: 2020
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: This paper studies two classes of variational problems introduced in [7], related to the optimal shapes of tree roots and branches. Given a measure $μ$ describing the distribution of leaves, a sunlight functional $§(μ)$ computes the total amount of light captured by the leaves. For a measure $μ$ describing the distribution of root hair cells, a harvest functional $\H(μ)$ computes the total amount of water and nutrients gathered by the roots. In both cases, we seek a measure $μ$ that maximizes these functionals subject to a rami?ed transportation cost, for transporting nutrients from the roots to the trunk or from the trunk to the leaves. Compared with [7], here we do not impose any a priori bound on the total mass of the optimal measure $μ$, and more careful a priori estimates are thus required. In the unconstrained optimization problem for branches, we prove that an optimal measure exists, with bounded support and bounded total mass. In the unconstrained problem for tree roots, we prove that an optimal measure exists, with bounded support but possibly unbounded total mass. The last section of the paper analyzes how the size of the optimal tree depends on the parameters defining the various functionals.
Additional file 5 of Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans
Creators: name: J. Alexander-Floyd
name: S. Haroon
name: M. Ying
name: A. Entezari
name: C. Jaeger
name: M. Vermulst
name: T. Gidalevitz
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Evolutionary Biology
subject: Ecology
subject: Developmental Biology

description: Additional file 5: Table S1. Loss-of-function analysis for the RIL2-like head aggregation phenotype. sDP2 free duplication covers most of the left arm of chromosome I, extending through dpy-5 marker but not through unc-13. drxIR1;Q40 animals were crossed with KR292 [him-1(h55);dpy-5(e61);unc-13(e450)I; sDp2(I;f)], F1 progeny that either did (based on segregation of unc non-dpy phenotype among their progeny) or did not inherit the sDp2 duplication were singled, and their F2 progeny scored for the increased ratio of head to body aggregation (RIL2-like) and the dumpy phenotypes. The RIL2-like phenotype behaved genetically as did the known loss-of-function dpy-5(e61) allele.
Molecular modeling studies of pyrrolo[2,3-d]pyrimidin-4-amine derivatives as JAK1 inhibitors based on 3D-QSAR, molecular docking, molecular dynamics (MD) and MM-PBSA calculations
Creators: name: Seketoulie Keretsu
name: Swapnil P. Bhujbal
name: Cho, Seung Joo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Rheumatoid Arthritis (RA) is an autoimmune disease caused by overproduction of pro-inflammatory cytokines. Janus Kinases (JAKs) mediate cytokines signaling through the Janus Kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathways. Clinical studies have shown that Janus kinase 1 (JAK1) mediated signaling plays a key role in synovial response in rheumatoid arthritis. Hence, the inhibition JAK1 is considered as an important therapeutic route for treatment of rheumatoid arthritis. In this study, we have performed three-dimensional quantitative structure-activity relationship (3 D-QSAR), molecular docking, molecular dynamics (MD) and free energy calculations on a series of pyrrolo[2,3-d]pyrimidin-4-amine JAK1 inhibitors. Molecular docking studies of the compounds 03, 13, 36 and 49 with JAK1 were performed to study the binding interactions. The binding conformations of the compounds from docking studies were selected based on binding energy and H-bond interactions and were used as initial structure for MD simulations. Using 3 D-QSAR techniques, a ligand-based comparative molecular field analysis (CoMFA) model (q2 = 0.5, r2 = 0.96) and a receptor-based CoMFA model (q2 = 0.78, r2 = 0.98) were developed. Analysis of the MD results of the most active compound (compound 49) with JAK1 showed the formation of H-bond interactions with residues Glu957, Leu959 and Gly887 and water-mediated H-bond interaction with Gly887 and His885. Based on the contour map analyses of the receptor-based CoMFA, a design strategy was proposed and was used for designing new JAK1 inhibitors. Four of the designed compounds (D57, D58, D98 and D99) showed predicted activity values (pIC50> 8.8) greater than the most active compound for JAK1. MM-PBSA based free energy calculations indicated that the designed compounds were able to form stable binding with JAK1 primarily through electrostatic interactions and van der Waal interactions. Collectively, the outcome of this study can be used to further the progress of JAK1 inhibition for the treatment of rheumatoid arthritis. Communicated by Ramaswamy H. Sarma
SyZyGy: A Straight Interferometric Spacecraft System for Gravity Wave Observations
Creators: name: Estabrook, F. B.
name: Armstrong, J. W.
name: Tinto, Massimo
name: Folkner, William
Publisher: name: arXiv
Year: 2003
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We apply TDI, unfolding the general triangular configuration, to the special case of a linear array of three spacecraft. We show that such an array ("SyZyGy") has, compared with an equilateral triangle GW detector of the same scale, degraded (but non-zero) sensitivity at low-frequencies (f<
description: 13 pages, 6 figures; typos corrected, figure modified, references added