cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dificultades en el aprendizaje de la estadística
Creators: name: Méndez Marín, Miguel Ángel
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Aprendizaje - Enseñanza
subject: Educación - Aspectos sociales
subject: Practicas de la enseñanza - Estadísticas
subject: Estadística
subject: Dificultades
subject: Actitudes
subject: Conocimientos

description: Este trabajo de grado refleja las dificultades en el aprendizaje de la Estadística Descriptiva asociadas a los conocimientos y actitudes de 88 estudiantes de primer semestre de la Facultad de Ciencias Sociales y Humanas de la Universidad Externado de Colombia en el semestre 2022 -2 por medio de dos instrumentos haciendo uso de la investigación cualitativa, realizando un tipo de estudio descriptivo interpretativo. El primer instrumento asociado a las actitudes es el SATS-20 el cual mide los sentimientos, la importancia o utilidad, los conocimientos o habilidades, y la dificultad de la Estadística como materia. El segundo instrumento mide el nivel de conocimientos básicos en Estadística, por medio de preguntas sobre temas como tablas, gráficos, medidas de tendencia central y medidas de dispersión. Como conclusión los estudiantes llegaron con algunos conocimientos en los diferentes temas básicos, en especial lectura de tablas y gráficos, pero con vacíos en representaciones numéricas y con respecto a las actitudes reconocieron la utilidad e importancia de la Estadística dentro de sus profesiones y sus vidas personales, aunque ven la Estadística como una asignatura difícil de abordar debido a su tecnicismo, cálculos y fórmulas, y a pesar de ello, están seguros que PUEDEN APRENDER ESTADÍSTICA.
description: This research study reflects the difficulties in learning Descriptive Statistics associated with the knowledge and attitudes of 88 first-semester students of the Faculty of Social and Human Sciences at Universidad Externado de Colombia in the semester 2022 -2 by means of two instruments using qualitative research, performing an interpretative descriptive type of study. The first instrument associated with attitudes is the SATS-20 which measures feelings, importance or usefulness, knowledge or skills, and the difficulty of Statistics as a subject. The second instrument measures the level of basic knowledge in Statistics, by means of questions on topics such as tables, graphs, measures of central tendency, and measures of dispersion. In conclusion, the students arrived with some knowledge about different basic topics, especially reading tables and graphs, but with gaps in numerical representations, regarding the attitudes they recognize the usefulness and importance of Statistics within their professions and their personal lives, although they see Statistics as a difficult subject to approach due to its technicality, calculations, and formulas, nevertheless, they are sure that they CAN LEARN STATISTICS.
Hybrid Message Passing-Based Detectors for Uplink Grant-Free NOMA Systems
Creators: name: Song, Yi
name: Zhu, Yiwen
name: Chen-Hu, Kun
name: Lu, Xinhua
name: Sun, Peng
name: Wang, Zhongyong
Publisher: name: arXiv
Year: 2024
Subjects: subject: Information Theory (cs.IT)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This paper studies improving the detector performance which considers the activity state (AS) temporal correlation of the user equipments (UEs) in the time domain under the uplink grant-free non-orthogonal multiple access (GF-NOMA) system. The Bernoulli Gaussian-Markov chain (BG-MC) probability model is used for exploiting both the sparsity and slow change characteristic of the AS of the UE. The GAMP Bernoulli Gaussian-Markov chain (GAMP-BG-MC) algorithm is proposed to improve the detector performance, which can utilize the bidirectional message passing between the neighboring time slots to fully exploit the temporally-correlated AS of the UE. Furthermore, the parameters of the BG-MC model can be updated adaptively during the estimation procedure with unknown system statistics. Simulation results show that the proposed algorithm can improve the detection accuracy compared with the existing methods while keeping the same order complexity.
Efecto de la cátedra de paz en la cotidianidad de adolescentes entre 12 y 14 años en tres instituciones educativas en la ciudad de Bogotá
Creators: name: Parra Orjuela, Mónica Patricia
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Paz - Aspectos sociales
subject: Pedagogía - Enseñanza
subject: Educación de niños
subject: Cátedra de paz
subject: Cultura de paz
subject: Educación para la paz
subject: Resolución de conflictos
subject: Convivencia

description: Trabajo de grado que se propone evaluar los efectos que ha tenido la Cátedra de Paz en la aprehensión de conceptos bajo el contexto de la Cultura para la paz, tales como: paz, violencia, conflicto, convivencia y cómo pueden estos conocimientos influenciar en la resolución de conflictos que se presentan en su cotidianidad. Para tal fin se realiza un análisis cuantitativo para hacer una comparación interinstitucional y un análisis cualitativo con el fin de entender los significados y experiencias de cada estudiante bajo un enfoque fenomenológico hermenéutico. Los resultados arrojaron diferencias entre tres distintas formas de impartir la Cátedra de Paz. Las encuestas y entrevistas se aplicaron a estudiantes entre 12 y 14 años, edad en la que se inicia la construcción de una moral más autónoma, pero que está fuertemente influenciada por los conocimientos adquiridos tanto en la familia como en la escuela. Con estos resultados se espera tomar los elementos fuertes de cada estilo de Cátedra y trabajar en los puntos débiles con el fin de generar un impacto positivo en cada estudiante y crear una verdadera cultura de paz, que es la apuesta que se ha hecho como país tras la firma de los acuerdos de paz.
description: The purpose of this thesis is evaluate the effects produced by the subject “Chair of peace” in the apprehension of the concepts under the Peace Culture context, such as Peace, violence, conflict, context, and how this knowledge influences the daily conflict resolution. To get that target, a quantitative analysis is made to make an inter-institutional comparison and a qualitative analysis with the purpose of understand the meaning and experiences of each student under a phenomenological hermeneutical approach. The results show differences between three different ways to interpret the peace chair. The surveys and interviews applied to the students among 12 and 14 years, age where starts the most autonomous Moral construction, but that is strongly influenced by the knowledge acquired in the family as the school as well. With these results, it expects to take advantage of the strong points and reinforce the weak ones with the purpose of generate a positive impact in every student and create a truly peace culture, which is the bet made after the signature of the peace agreements made in Colombia.
Supplemental Material, sj-pdf-2-het-10.1177_09603271211025599 - Antisickling effect of chrysin is associated with modulation of oxygenated and deoxygenated haemglobin via alteration of functional chemistry and metabolic pathways of human sickle erythrocytes
Creators: name: Nwankwo, HC
name: Idowu, AA
name: Muhammad, A
name: Waziri, AD
name: Abubakar, YS
name: Bashir, M
name: Erukainure, OL
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental Material, sj-pdf-2-het-10.1177_09603271211025599 for Antisickling effect of chrysin is associated with modulation of oxygenated and deoxygenated haemglobin via alteration of functional chemistry and metabolic pathways of human sickle erythrocytes by HC Nwankwo, AA Idowu, A Muhammad, AD Waziri, YS Abubakar, M Bashir and OL Erukainure in Human & Experimental Toxicology
Hierarchical binary black hole mergers in globular clusters: mass function and evolution with redshift
Creators: name: Torniamenti, Stefano
name: Mapelli, Michela
name: Périgois, Carole
name: Sedda, Manuel Arca
name: Artale, M. Celeste
name: Dall'Amico, Marco
name: Vaccaro, M. Paola
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Hierarchical black hole (BH) mergers are one of the most straightforward mechanisms to produce BHs inside and above the pair-instability mass gap. Here, we investigate the impact of globular cluster (GC) evolution on hierarchical mergers, and we account for the uncertainties related to BH mass pairing functions on the predicted primary BH mass, mass ratio and spin distribution. We find that the evolution of the host GC quenches the hierarchical BH assembly already at the third generation, mainly due to cluster expansion powered by a central BH sub-system. Hierarchical mergers match the primary BH mass distribution from GW events for $m_1 > 50 \, \mathrm{M_{\odot}}$, regardless of the assumed BH pairing function. At lower masses, however, different pairing functions lead to dramatically different predictions on the primary BH mass merger rate density. We find that the primary BH mass distribution evolves with redshift, with a larger contribution from mergers with $m_1 \geq 30 \, \mathrm{M_{\odot}}$ for $z\geq{}2$. Finally, we calculate the mixing fraction of BBHs from GCs and isolated binary systems. Our predictions are very sensitive to the spins, which favor a large fraction ($>0.6$) of BBHs born in GCs, in order to reproduce misaligned spin observations.
description: 18 pages, 15 figures, 1 table. Comments welcome
Outbreak of West Nile virus infection in humans, Romania, July to October 2010
Creators: name: Sirbu, A.
name: Ceianu, C. S.
name: Panculescu-Gatej, R. I.
name: Vázquez, A.
name: Tenorio, Antonio
name: Rebreanu, R.
name: Niedrig, Matthias
name: Nicolescu, G.
name: Pistol, A.
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2011
Subjects: subject: Adolescent
subject: Humans
subject: Female
subject: Polymerase Chain Reaction
subject: Disease Outbreaks
subject: Male
subject: Middle Aged
subject: Incidence
subject: West Nile Fever/diagnosis
subject: Adult
subject: Aged
subject: Age Distribution
subject: Immunoglobulin M/blood
subject: Enzyme-Linked Immunosorbent Assay
subject: Young Adult
subject: Sex Distribution
subject: Aged 80 and over
subject: Immunoglobulin G/blood
subject: Antibodies Viral/blood
subject: Antibodies Viral/cerebrospinal fluid
subject: Romania/epidemiology
subject: West Nile Fever/epidemiology
subject: West Nile virus/genetics
subject: West Nile virus/isolation & purification
subject: 610 Medizin

description: A total of 57 cases of West Nile virus infection (54 with neuroinvasive infection and three with fever) were identified in Romania between July and October 2010. The median age of the cases was 53.4 years, with the highest incidence in the age group 60–69 years. The case fatality rate was 8.8%. Cases were distributed in 19 districts in the southern, western, central and eastern parts of the country. Molecular investigation revealed lineage 2 West Nile virus, related to the Volgograd 2007 strain.
Talleres virtuales culturales durante los tiempos de la pandemia del Sars-Cov-2, 2020-2021
Creators: name: Wohlgemuth Neira, Simón Jesús
Publisher: name: Universidad Externado de Colombia
Year: 2022
Subjects: subject: Pedagogía - Enseñanza
subject: Talleres - Enseñanza
subject: Educación - Aspectos sociales
subject: Tallere(s)
subject: Covid 19
subject: Biblioteca Nacional de Colombia
subject: Analisis documental

description: La Biblioteca Nacional de Colombia dictó, en los años 2020 y 2021, muchas actividades virtuales, entre ellas lo que este trabajo ha denominado talleres virtuales culturales. Sin embargo, los motivos por los que un taller virtual cultural tenía una buena recepción entre el público era desconocido, resolver este enigma es lo que motiva la presente investigación. Esta investigación busca, partiendo de las metodologías de los talleres virtuales culturales con mayor y menos asistencia, dictados en la Biblioteca Nacional de Colombia durante los años 2020 y 2021, y de sus cifras de asistencia; los motivos por los que se presentan diferencias tan grandes, en términos de asistencia, entre un año y otro. Para hacerlo revisa cuidadosamente si es pertinente llamarlos talleres virtuales culturales y sí el hecho de que lo sean o no es un factor que afecta dicha cifra.
description: The National Library of Colombia dictated, in the years 2020 and 2021, a varied number of virtual activities, among those what this investigation has called “virtual cultural workshops”. The motives for which this workshops had a certain amount of attendees was a mystery, and resolve it was the main project of this paper. This investigation provides, utilizing the metodologies of the workshops given to the author by the National Library of Colombia (BNC) during the years 2020 and 2021 and their assistance data; the motives for which the assistance varied so much between the ones that were in the upper bracket and the ones that were all the way to the bottom in terms of assistance, between one year and the next. The paper, explores the posibility of the metodologie being a proper one for what is called a virtual culturl workshop in order to see if it has any impact in the assitance data.
Ambitions for theory in the physics of life
Creators: name: Bialek, William
Publisher: name: arXiv
Year: 2024
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Molecular Networks (q-bio.MN)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Theoretical physicists have been fascinated by the phenomena of life for more than a century. As we engage with more realistic descriptions of living systems, however, things get complicated. After reviewing different reactions to this complexity, I explore the optimization of information flow as a potentially general theoretical principle. The primary example is a genetic network guiding development of the fly embryo, but each idea also is illustrated by examples from neural systems. In each case, optimization makes detailed, largely parameter-free predictions that connect quantitatively with experiment
description: Lectures at the 2023 Les Houches Summer School, Theoretical Biophysics. Revisions include some replacement figures with permissions, small clarifications in the text
sj-pdf-1-jla-10.1177_24726303211021790 – Supplemental material for Optimal Scheduling for Laboratory Automation of Life Science Experiments with Time Constraints
Creators: name: Itoh, Takeshi D.
name: Horinouchi, Takaaki
name: Uchida, Hiroki
name: Takahashi, Koichi
name: Ozaki, Haruka
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-jla-10.1177_24726303211021790 for Optimal Scheduling for Laboratory Automation of Life Science Experiments with Time Constraints by Takeshi D. Itoh, Takaaki Horinouchi, Hiroki Uchida, Koichi Takahashi and Haruka Ozaki in SLAS Technology
sj-pdf-2-nnr-10.1177_15459683211028245 – Supplemental Material for Acute Brain-Derived Neurotrophic Factor DNA Methylation Trajectories in Cerebrospinal Fluid and Associations With Outcomes Following Severe Traumatic Brain Injury in Adults
Creators: name: Treble-Barna, Amery
name: Heinsberg, Lacey W.
name: Puccio, Ava M.
name: Shaffer, John R.
name: Okonkwo, David O.
name: Beers, Sue R.
name: Weeks, Daniel E.
name: Conley, Yvette P.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: Neuroscience

description: Supplemental Material, sj-pdf-2-nnr-10.1177_15459683211028245 for Acute Brain-Derived Neurotrophic Factor DNA Methylation Trajectories in Cerebrospinal Fluid and Associations With Outcomes Following Severe Traumatic Brain Injury in Adults by Amery Treble-Barna, Lacey W. Heinsberg, Ava M. Puccio, John R. Shaffer, David O. Okonkwo, Sue R. Beers, Daniel E. Weeks and Yvette P. Conley in Neurorehabilitation and Neural Repair
Anomalous quantum transport in fractal lattices
Creators: name: Rojo-Francàs, Abel
name: Pansari, Priyanshu
name: Bhattacharya, Utso
name: Juliá-Díaz, Bruno
name: Grass, Tobias
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Fractal lattices are self-similar structures with repeated patterns on different scales. As in other aperiodic lattices, the absence of translational symmetry can give rise to quantum localization effects. In contrast to low-dimensional disordered systems, co-existence of localized and extended states is possible in fractal structures, and can lead to subtle transport behavior. Here, we study the dynamical properties of two fractal lattices, the Sierpiński gasket and the Sierpiński carpet. Despite their geometric similarity, the transport turns out to behave very differently: In the Sierpiński gasket, we find a sub-diffusive behavior, whereas the Sierpiński carpet exhibits sub-ballistic transport properties. We show that the different dynamical behavior is in line with qualitative differences of the systems' spectral properties. Specifically, in contrast to the Sierpiński carpet, the Sierpiński gasket exhibits an inverse power-law behavior of the level spacing distribution. From the point of view of technological applications, we demonstrate that the sub-diffusive behavior in the Sierpiński gasket can be used as a quantum memory. By interpolating between fractal and regular lattices, a flexible tuning between different transport regimes becomes possible.
description: 9 pages, 7 figures
sj-pdf-2-jfm-10.1177_1098612X211021538 – Supplemental material for 2021 AAFP Feline Senior Care Guidelines
Creators: name: Ray, Michael
name: Carney, Hazel C
name: Boynton, Beth
name: Quimby, Jessica
name: Robertson, Sheilah
name: St Denis, Kelly
name: Tuzio, Helen
name: Wright, Bonnie
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-pdf-2-jfm-10.1177_1098612X211021538 for 2021 AAFP Feline Senior Care Guidelines by Michael Ray, Hazel C Carney, Beth Boynton, Jessica Quimby, Sheilah Robertson, Kelly St Denis, Helen Tuzio and Bonnie Wright in Journal of Feline Medicine and Surgery
Use and subjective experience of the impact of motor-assisted movement exercisers in people with amyotrophic lateral sclerosis: a multicenter observational study
Creators: name: Maier, André
name: Gaudlitz, Marcel
name: Grehl, Torsten
name: Weyen, Ute
name: Steinbach, Robert
name: Grosskreutz, Julian
name: Rödiger, Annekathrin
name: Koch, Jan Christoph
name: Lengenfeld, Teresa
name: Weydt, Patrick
name: Günther, René
name: Wolf, Joachim
name: Baum, Petra
name: Metelmann, Moritz
name: Dorst, Johannes
name: Ludolph, Albert C.
name: Kettemann, Dagmar
name: Norden, Jenny
name: Koc, Ruhan Yasemin
name: Walter, Bertram
name: Hildebrandt, Barbara
name: Münch, Christoph
name: Meyer, Thomas
name: Spittel, Susanne
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Motor-assisted movement exercisers (MME)
subject: Subjective experience
subject: Net Promoter Score (NPS)
subject: Symptom improvement
subject: High-frequency use
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Motor-assisted movement exercisers (MME) are devices that assist with physical therapy in domestic settings for people living with ALS. This observational cross-sectional study assesses the subjective experience of the therapy and analyzes users' likelihood of recommending treatment with MME. The study was implemented in ten ALS centers between February 2019 and October 2020, and was coordinated by the research platform Ambulanzpartner. Participants assessed symptom severity, documented frequency of MME use and rated the subjective benefits of therapy on a numerical scale (NRS, 0 to 10 points, with 10 being the highest). The Net Promotor Score (NPS) determined the likelihood of a participant recommending MME. Data for 144 participants were analyzed. Weekly MME use ranged from 1 to 4 times for 41% of participants, 5 to 7 times for 42%, and over 7 times for 17%. Particularly positive results were recorded in the following domains: amplification of a sense of achievement (67%), diminution of the feeling of having rigid limbs (63%), diminution of the feeling of being immobile (61%), improvement of general wellbeing (55%) and reduction of muscle stiffness (52%). Participants with more pronounced self-reported muscle weakness were more likely to note a beneficial effect on the preservation and improvement of muscle strength during MME treatment (p < 0.05). Overall, the NPS for MME was high (+ 61). High-frequency MME-assisted treatment (defined as a minimum of five sessions a week) was administered in the majority of participants (59%) in addition to physical therapy. Most patients reported having achieved their individual therapeutic objectives, as evidenced by a high level of satisfaction with MME therapy. The results bolster the justification for extended MME treatment as part of a holistic approach to ALS care.
A new understanding of the Gemini-Monoceros X-ray enhancement from discoveries with eROSITA
Creators: name: Knies, Jonathan R.
name: Sasaki, Manami
name: Becker, Werner
name: Liu, Teng
name: Ponti, Gabriele
name: Plucinsky, Paul P.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The Gemini-Monoceros X-ray enhancement is a rich field for studying diffuse X-ray emission and supernova remnants (SNRs). With the launch of eROSITA onboard the SRG platform in 2019, we are now able to fully study these sources. Many of the SNRs in the vicinity are suspected to be very old remnants, which are severely understudied in X-rays due to numerous observational challenges. In addition, identification of new faint large SNRs might help to solve the long-standing discrepancy of observed and expected number of Galactic SNRs.
 We performed a detailed X-ray spectral analysis of the entire diffuse structure and a detailed background analysis of the vicinity. We also made use of multi-wavelength data to better understand the morphology and to constrain the distances to the different sources. We estimated the plasma properties of the sources and calculated a grid of model SNRs to determine the individual SNR properties.
 Most of the diffuse plasma of the Monogem Ring SNR is well described by a single non-equilibrium ionization (NEI) component with an average temperature of $kT = 0.14\pm 0.03$ keV. We obtain an age of $\approx 1.2\cdot 10^5$ yr - consistent with PSR B0656+14 - for the Monogem Ring. In the south-east, we found evidence for a hotter second plasma component and a possible new SNR candidate at $\approx 300$ pc, with the new candidate having an age of $\approx 50,000$ yr. We were also able to improve on previous studies on the more distant Monoceros Loop and PKS 0646+06 SNRs. We obtained significantly higher temperatures than previous studies, and for PKS 0646+06 a much lower estimated age of the SNR. We also found a new SNR candidate G190.4+12.5 which most likely is located at $D > 1.5 $ kpc, expanding into a low density medium at a high distance from the Galactic plane, with an estimated age of $40,000-60,000$ yr.
description: Accepted by A&A - 02/04/2024
Association of eating duration less than 8 hours with all-cause, cardiovascular, and cancer mortality
Creators: name: Chen
Publisher: name: Zenodo
Year: 2024

description: This repository contains code and demo data used to generate the results of the main analysis of the article “Association of eating duration less than 8 hours with all-cause, cardiovascular, and cancer mortality”.

Codes are provided for transparency and in the spirit of scientific collaboration. We will not be able to answer questions about the details of these codes.

Contents Guide

The Data folder contains:  

· "test.sas7bdat": This dataset contains 5000 samples extracted from the clean data, which was created by merging all rounds of NHANES from 2003–2004 to 2017–2018 and all preprocessing steps described in the paper have been applied. Original NHANES data can be downloaded at https://wwwn.cdc.gov/nchs/nhanes/Default.aspx. The mortality status and underlying cause of death of adult participants can be found in the public-use linked mortality files, which can be download at https://www.cdc.gov/nchs/data-linkage/mortality-public.htm.

· "test_bmr75.sas7bdat": This dataset contains 5,000 samples extracted from the dataset used for sensitivity analyse 1, which used self-reported daily energy intake <75% of the Mifflin-St.Jeor predicted energy requirement to exclude participants.

· "test_sensitivity.sas7bdat": This dataset contains 5,000 samples extracted from the dataset used for sensitivity analyse 5, which used daily energy intake <800 or >8000 kcal for men and <600 or >6000 kcal for women to exclude participants with implausible caloric intake, a commonly used exclusion criterion in nutritional epidemiology.

The Statistical codes document contains: 

· SAS code used for Figure 2 cause-specific mortality&Table 3-4

· R code for Table 1

· R code for Figure 2 all-cause mortality

· R code for Table 2 absolute risk

The Demo-output folder contains: 

· Baseline characteristics.html

· CVD mortality HR results.CSV

· Cancer mortality HR results.CSV

· All-cause mortality forest

· Subgroup results.CSV

· Sensitivity results.CSV

· ARD for overall sample

· ARD for people with CVD or diabetes

All data preprocessing and cause-specific hazard model analyses were performed using SAS (version 9.4). The forest plots and absolute risk difference calculations were conducted in R (version 4.2.2), using R packages:

forestploter, version 1.1.2;

riskRegression, version 2023.12.21;

pec, version 2023.04.12.
Disease relevance of rare VPS13B missense variants for neurodevelopmental Cohen syndrome
Creators: name: Zorn, Malte
name: Kühnisch, Jirko
name: Bachmann, Sebastian
name: Seifert, Wenke
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Cohen Syndrome
subject: VPS13B Missense Variants
subject: Golgi Complex
subject: Neurodevelopmental Disorder
subject: Pathomechanism
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Autosomal recessive Cohen syndrome is a neurodevelopmental disorder characterized by postnatal microcephaly, intellectual disability, and a typical facial gestalt. Genetic variants in VPS13B have been found to cause Cohen syndrome, but have also been linked to autism, retinal disease, primary immunodeficiency, and short stature. While it is well established that loss-of-function mutations of VPS13B cause Cohen syndrome, the relevance of missense variants for the pathomechanism remains unexplained. Here, we investigate their pathogenic effect through a systematic re-evaluation of clinical patient information, comprehensive in silico predictions, and in vitro testing of previously published missense variants. In vitro analysis of 10 subcloned VPS13B missense variants resulted in full-length proteins after transient overexpression. 6/10 VPS13B missense variants show reduced accumulation at the Golgi complex in the steady state. The overexpression of these 6/10 VPS13B missense variants did not rescue the Golgi fragmentation after the RNAi-mediated depletion of endogenous VPS13B. These results thus validate 6/10 missense variants as likely pathogenic according to the classification of the American College of Medical Genetics through the integration of clinical, genetic, in silico, and experimental data. In summary, we state that exact variant classification should be the first step towards elucidating the pathomechanisms of genetically inherited neuronal diseases.
Discovery of the Goat Horn complex: a $\sim 1000$ deg$^2$ diffuse X-ray source connected to radio loop XII
Creators: name: Locatelli, Nicola
name: Ponti, Gabriele
name: Merloni, Andrea
name: Zheng, Xueying
name: Dennerl, Konrad
name: Haberl, Frank
name: Maitra, Chandreyee
name: Sanders, Jeremy
name: Sasaki, Manami
name: Zhang, Heshou
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: A dozen of patches of polarized radio emission spanning tens of degrees in the form of coherent and stationary loops are observed at radio frequencies across the sky. Their origin is usually associated to nearby shocks, possibly arising from close supernovae explosions. The origin of the radio Loop XII remains so far unknown. We report an anti-correlation of the radio polarized emission of loop XII with a large patch of soft X-ray emission found with SRG/eROSITA in excess of the background surface brightness, in the same region. The soft X-ray seemingly coherent patch in excess of the background emission, which we dub as the Goat Horn complex, extends over a remarkable area of $\sim 1000$ deg$^2$ and includes an arc-shaped enhancement potentially tracing a cold front. An anti-correlation of the X-ray intensity with the temperature of the plasma responsible for the X-ray emission is also observed. The X-ray bright arc seems to anticipate the radio loop XII by some degrees on the sky. This behavior can be recast in terms of a correlation between X-ray surface brightness and radio depolarization. We explore and discuss different possible scenarios for the source of the diffuse emission in the Goat Horn complex: a large supernova remnant; an outflow from active star formation regions in nearby Galactic spiral arms; a hot atmosphere around the Large Magellanic Cloud. In order to probe these scenarios further, a more detailed characterization on the velocity of the hot gas is required.
description: 12 pages, 14 figures
The SRG/eROSITA All-Sky Survey: SRG/eROSITA cross-calibration with Chandra and XMM-Newton using galaxy cluster gas temperatures
Creators: name: Migkas, K.
name: Kox, D.
name: Schellenberger, G.
name: Veronica, A.
name: Pacaud, F.
name: Reiprich, T. H.
name: Bahar, Y. E.
name: Balzer, F.
name: Bulbul, E.
name: Comparat, J.
name: Dennerl, K.
name: Freyberg, M.
name: Garrel, C.
name: Ghirardini, V.
name: Grandis, S.
name: Kluge, M.
name: Liu, A.
name: Ramos-Ceja, M. E.
name: Sanders, J.
name: Zhang, X.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Galaxy cluster gas temperatures ($T$) play a crucial role in many cosmological and astrophysical studies. However, it has been shown that $T$ measurements can vary between different X-ray telescopes. These $T$ biases can propagate to several cluster applications for which $T$ can be used. Thus, it is important to accurately cross-calibrate X-ray instruments to account for systematic biases. In this work, we present the cross-calibration between SRG/eROSITA and Chandra/ACIS, and between SRG/eROSITA and XMM-Newton/EPIC, using for the first time a large sample of galaxy cluster $T$. To do so, we use the first eROSITA All-Sky Survey data and a large X-ray flux-limited cluster catalog. We measure X-ray $T$ for 186 independent cluster regions with both SRG/eROSITA and Chandra/ACIS in a self-consistent way, for three energy bands; 0.7-7 keV (full), 0.5-4 keV (soft), and 1.5-7 keV (hard). We do the same with SRG/eROSITA and XMM-Newton/EPIC for 71 different cluster regions and all three bands. We find that SRG/eROSITA measures systematically lower $T$ than the other two instruments. For the full band, SRG/eROSITA returns 20$\%$ and 14$\%$ lower $T$ than Chandra/ACIS and XMM-Newton/EPIC respectively, when the two latter instruments measure $k_{\text{B}}T\approx 3$ keV each. The discrepancy increases to 38\% and 32\% when Chandra/ACIS and XMM-Newton/EPIC measure $k_{\text{B}}T\approx 10$ keV respectively. For low-$T$ galaxy groups, the discrepancy becomes milder. The soft band shows a marginally lower discrepancy than the full band. In the hard band, the cross-calibration of SRG/eROSITA and the other instruments show stronger differences. We could not identify any possible systematic biases that significantly alleviated the tension. Finally, we provide conversion factors between SRG/eROSITA, Chandra/ACIS, and XMM-Newton/EPIC $T$ which will be beneficial for future cluster studies.
description: 24 pages, 15 figures, accepted in A&A (updated published version, replaced the submitted version v1)
Variation of elemental concentration in leather during post-tanning operation using energy dispersive X-ray fluorescence spectroscopy: principal component analysis approach
Creators: name: Nalyanya, Kallen Mulilo
name: Rop, Ronald K.
name: Onyuka, Arthur S.
name: Birech, Zephania
name: Okonda, Justus J.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry

description: Leather processing employs a series of heavy chemicals that are detrimental to human health and environment at different stages of tanning. Determination of the elemental concentrations becomes complex especially using the conventional techniques since they involve tracking individual elements at different stages of leather-making processes. The study investigated the effect of crusting operations on the elemental concentrations using energy dispersive X-ray fluorescence (EDXRF) and principal component analysis (PCA). The spectral measurements of the post-tanned samples were carried out in vacuum using EDXRF-Rigaku NEX CG. The concentrations of elements were determined by advanced FP (fundamental Parameter) software-RPF-SQX (Rigaku Profile Fitting-Spectra Quant X) software. The abundance of the elements in the leather crusts was in the order Cr > S > Na > Cl > Al > Si > Ca > V > K > P > Zr > Zn > Fe > Mn > As > Ti > Cu > Pb > Ni > Ga > Br > Hg. The concentration levels for the majority of the elements in the crusts were higher than the recommended safe extractible levels for leather. Combination of EDXRF and principal component analysis in this study has shown potential in the leather industry to monitor the chemical concentrations. A combination of Cu and RX9 secondary targets exhibited sufficient and excellent excitation efficiency for detection of the majority of elements in leather crusts. The valuable tracers for classification in the crusting operations are Cr, S, Cl, P, V, K, Mn and Zn. Retanning process increases S and Cu whereas levels of Cl decrease in the crusts. Dyeing and Fatliquoring processes raise the concentration levels of S while decreasing the Cl level.
Listeriosis outbreak caused by acid curd cheese ‘Quargel’, Austria and Germany 2009
Creators: name: Fretz, Rainer
name: Sagel, U.
name: Ruppitsch, W.
name: Pietzka, A. T.
name: Stöger, A.
name: Huhulescu, S.
name: Heuberger, S.
name: Pichler, J.
name: Much, P.
name: Pfaff, Günter
name: Stark, Klaus
name: Prager, Rita
name: Flieger, Antje
name: Feenstra, O.
name: Allerberger, F.
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Aged
subject: 80 and over
subject: Humans
subject: Female
subject: Disease Outbreaks
subject: Germany/epidemiology
subject: Male
subject: Middle Aged
subject: Food Microbiology
subject: Cheese/microbiology
subject: Austria/epidemiology
subject: Foodborne Diseases/epidemiology
subject: Listeria Infections/epidemiology
subject: 610 Medizin

description: We report an outbreak of listeriosis in Austria and Germany due to the consumption of ‘Quargel’ cheese produced by an Austrian manufacturer. At the time of writing this report, the outbreak was known to account for 14 outbreak cases in 2009, including four cases with lethal outcome. On 23 January 2010, the cheese product was voluntarily withdrawn from the market.
Differentially Unwell: On Mimi Khúc’s “dear elia”
Creators: name: Chu, Seo-Young
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Asian Americans
subject: American literature--Asian American authors
subject: Mental health
subject: Mental illness
subject: Post-traumatic stress disorder
subject: Psychic trauma
subject: Suicide
subject: Korean Americans
subject: Suffering

description: [...] Inviting readers to reclaim the stigma of unwellness and collectively to “tend to our unwellness, together,” Khúc approaches unwellness as a crucial resource for subverting the “wellness and unwellness” dichotomy entirely. After all, the opposite of “wellness” is not “unwellness”; the opposite of “wellness” does not exist. The opposition itself is an artificial framework, one that reductively harms more than it dialogically helps. We need to move away from these simplistic dualisms, Khúc suggests, and towards more generous, trauma-informed epistemologies. [...]
A novel diatomite supported layered double hydroxide as reusable adsorbent for efficient removal of acidic dyes
Creators: name: Shamsayei, Maryam
name: Yamini, Yadollah
name: Asiabi, Hamid
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry

description: It would be of significance to design agreen composite for highly efficient uptake of contaminants. In this study, we fabricated an environmental friendly composite via insitu deposition of positively charged layered double hydroxide (LDH) on the surface of the negatively charged diatomite for efficient uptake of dye pollutants from aqueous solutions. The resulting LDH/diatomite (LDH/DIA) composites were characterised by X-ray diffraction (XRD), Fourier transformed infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), Energy-dispersive X-ray (EDX), and N2 adsorption–desorption technique. The uptake performances of the resulting LDH/DIA composites were evaluated for the uptake of anionic tartrazine (TR) and erythrosine (ER) dyes. The uptake test of dyes was performed at ambient temperature by dispersing 10mg of the LDH/DIA in 10mL of dye solutions at pH 8 and 6 for TA and ER, respectively. The results show that composite can rapidly reduce the concentration of dyes in aqueous solutions from 20mg L−1 to 0.0001mg L−1. In addition, the uptake behaviour of this new adsorbent fits well with the Freundlich isotherm and the pseudo-second-order kinetic model. Langmuir isotherm study showed that the maximum uptake capacities of TR and ER dyes over the LDH/DIA composite were 555.6 and 625.2mg g−1, respectively, which were much higher than those of the known adsorbents. Our results suggested that the LDH/DIA has great potential applications as environmentally friendly materials for the treatment of wastewater with high concentration of anionic dyes.
Long-term Evolution of Binary Orbits Induced by Circumbinary Disks
Creators: name: Valli, Ruggero
name: Tiede, Christopher
name: Vigna-Gómez, Alejandro
name: Cuadra, Jorge
name: Siwek, Magdalena
name: Ma, Jing-Ze
name: D'Orazio, Daniel J.
name: Zrake, Jonathan
name: de Mink, Selma E.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Circumbinary disks are found in a variety of astrophysical scenarios, spanning binary star formation to accreting supermassive black hole binaries. The interaction with a circumbinary disk can yield opposite effects on the binary orbit leading to circularization, or exciting the eccentricity, widening the orbit or shrinking it and facilitating mergers. We present a new formalism for the long-term evolution of the disk-binary interaction based on the results of recent suites of hydrodynamic simulations, which resolve the complex geometry of the gas in the vicinity of the binary and fully account for the gravitational and accretion forces. We release a python package, \texttt{spindler}, that implements our model. We show that, unless the mass reservoir feeding the disk is comparable to the mass of the binary, accretion onto the binary depletes the disk mass before inducing a significant change in orbital separation or mass ratio. This finding implies that, in most scenarios, interaction with a circumbinary disk is not an efficient mechanism to shrink the orbit of the binary. However, as long as the mass of the disk is at least a few percent of the mass of the binary, the interaction can excite the eccentricity up to an equilibrium value, and induce a statistical correlation between mass ratio and eccentricity. We consider the applicability of our model to a variety of astrophysical scenarios: during star formation, in evolved stellar binaries, triples and in supermassive black hole binaries. We discuss the theoretical and observational implications of our predictions.
description: 19 pages, 12 figures, 5 tables. Accepted in A&A. Comments welcome. Spindler available as a Python package on Zenodo: https://doi.org/10.5281/zenodo.10529060, and on github https://github.com/ruggero-valli/spindler. C-based version on https://github.com/ruggero-valli/spindler-c
Crimean-Congo hemorrhagic fever in Europe: current situation calls for preparedness
Creators: name: Maltezou, H. C.
name: Andonova, L.
name: Andraghetti, R.
name: Bouloy, M.
name: Ergonul, O.
name: Jongejan, F.
name: Kalvatchev, N.
name: Nichol, S.
name: Niedrig, Matthias
name: Platonov, A.
name: Thomson, Gail
name: Leitmeyer, Katrin
name: Zeller, Hervé
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Animals
subject: Humans
subject: Population Surveillance
subject: Risk Assessment
subject: Europe/epidemiology
subject: Hemorrhagic Fever
subject: Crimean/diagnosis
subject: Crimean/drug therapy
subject: Crimean/epidemiology
subject: Crimean/mortality
subject: Crimean/prevention & control
subject: Ticks/microbiology
subject: 610 Medizin

description: During the last decade Crimean-Congo hemorrhagic fever (CCHF) emerged and/or re-emerged in several Balkan countries, Turkey, southwestern regions of the Russian Federation, and the Ukraine, with considerable high fatality rates. Reasons for re-emergence of CCHF include climate and anthropogenic factors such as changes in land use, agricultural practices or hunting activities, movement of livestock that may influence host-tick-virus dynamics. In order to be able to design prevention and control measures targeted at the disease, mapping of endemic areas and risk assessment for CCHF in Europe should be completed. Furthermore, areas at risk for further CCHF expansion should be identified and human, vector and animal surveillance be strengthened.
Additional file 1 of Low awareness of the transitivity assumption in complex networks of interventions: a systematic survey from 721 network meta-analyses
Creators: name: Spineli, Loukia M.
name: Kalyvas, Chrysostomos
name: Yepes-Nuñez, Juan Jose
name: García-Sierra, Andrés Mauricio
name: Rivera-Pinzón, Diana C.
name: Seide, Svenja E.
name: Papadimitropoulou, Katerina
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy
Computational Biology

description: Additional file 1: Table S1. Results of the nmadb database [26] and a previous empirical study [25] of systematic reviews published between 01/2011 and 04/2015. Table S2. Results of pragmatic searches of systematic reviews published between 2016 and 2021. Table S3. List of verbatim on refraining from conducting network meta-analysis.
Epidemic conjunctivitis in Germany, 2004
Creators: name: Schrauder, Annette
name: Altmann, Doris
name: Laude, Gabriele
name: Claus, Hermann
name: Wegner, K
name: Köhler, R
name: Habicht-Thomas, H
name: Krause, Gérard
Publisher: name: Robert Koch-Institut
Year: 2006
Subjects: subject: Adolescent
subject: Preschool
subject: Newborn
subject: Humans
subject: Female
subject: Disease Outbreaks
subject: Germany/epidemiology
subject: Male
subject: Child
subject: Adult
subject: Sentinel Surveillance
subject: Infant
subject: Conjunctivitis/diagnosis
subject: Conjunctivitis/epidemiology
subject: Conjunctivitis/prevention & control
subject: 610 Medizin

description: Epidemic conjunctivitis can be associated with viral or bacterial pathogens, whereas epidemic keratoconjunctivitis is caused mainly by adenoviruses type 8,19 and 37. In Germany, the incidence of adenovirus conjunctivitis cases increased from 0.2 per 100 000 inhabitants (in 2001 and 2002) eventually to 0.5 in 2003 and 0.8 in 2004. The detection of adenovirus in conjunctival swabs is notifiable to the local health departments. Data about cases with positive conjunctival swabs are then transmitted to the Robert Koch-Institut. Quality control of data takes place and national surveillance data of confirmed cases with adenovirus conjunctivitis are published. From January to April 2004 the national surveillance system captured an outbreak with 1024 cases (131 laboratory confirmed). Analysis of the national surveillance data showed that in March 2004 the group primarily affected by epidemic keratoconjunctivitis was young men between 18 -29 years old followed by an increased number of notifications from women in the same age group. Meanwhile the German Armed Forces experienced an outbreak of conjunctivitis, almost exclusively without laboratory confirmation, affecting 6378 soldiers. Despite the small number of laboratory confirmed cases it became clear from the analysis of the national surveillance data that person-to-person transmission between young men and similar age groups of the population did occur. Whether the outbreak started within the garrisons of the German Armed Forces or whether it was triggered within these accommodations, there is clearly a need for the national and the military public health institutions to work together on guidelines to handle future challenges.
Agent Based Modelling for Archaeologists: How-to guide
Creators: name: Jutte, Annemarie
name: van der Knaap, Laura
name: Visser, Ronald
name: Rocks-Macqueen, Doug
name: Romanowska, Iza
name: Brughmans, Tom
name: Lambers, Karsten
name: Aitchison, Kenneth
Publisher: name: Zenodo
Year: 2024

description: How-to guide, giving an overview of the contents of each tutorial. Describes how to use the tutorials to learn specific skills.