cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry
Creators: name: Lauster, Daniel
name: Klenk, Simon
name: Ludwig, Kai
name: Nojoumi, Saba
name: Behren, Sandra
name: Adam, Lutz
name: Stadtmüller, Marlena
name: Saenger, Sandra
name: Zimmler, Stephanie
name: Hönzke, Katja
name: Yao, Ling
name: Hoffmann, Ute
name: Bardua, Markus
name: Hamann, Alf
name: Witzenrath, Martin
name: Sander, Leif E.
name: Wolff, Thorsten
name: Hocke, Andreas C.
name: Hippenstiel, Stefan
name: De Carlo, Sacha
name: Neudecker, Jens
name: Osterrieder, Klaus
name: Budisa, Nediljko
name: Netz, Roland
name: Böttcher, Christoph
name: Liese, Susanne
name: Herrmann, Andreas
name: Hackenberger, Christian P. R.
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: Nanoparticles
subject: biological interfaces
subject: Influenza virus entry
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Multivalent interactions at biological interfaces occur frequently in nature and mediate recognition and interactions in essential physiological processes such as cell-to-cell adhesion. Multivalency is also a key principle that allows tight binding between pathogens and host cells during the initial stages of infection. One promising approach to prevent infection is the design of synthetic or semisynthetic multivalent binders that interfere with pathogen adhesion1,2,3,4. Here, we present a multivalent binder that is based on a spatially defined arrangement of ligands for the viral spike protein haemagglutinin of the influenza A virus. Complementary experimental and theoretical approaches demonstrate that bacteriophage capsids, which carry host cell haemagglutinin ligands in an arrangement matching the geometry of binding sites of the spike protein, can bind to viruses in a defined multivalent mode. These capsids cover the entire virus envelope, thus preventing its binding to the host cell as visualized by cryo-electron tomography. As a consequence, virus infection can be inhibited in vitro, ex vivo and in vivo. Such highly functionalized capsids present an alternative to strategies that target virus entry by spike-inhibiting antibodies5 and peptides6 or that address late steps of the viral replication cycle.
MOESM3 of Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmonary Fibrosis
Creators: name: J. Fisher
name: M. Kolb
name: M. Algamdi
name: J. Morisset
name: K. Johannson
name: S. Shapera
name: P. Wilcox
name: T. To
name: M. Sadatsafavi
name: H. Manganas
name: N. Khalil
name: N. Hambly
name: A. Halayko
name: A. Gershon
name: C. Fell
name: G. Cox
name: C. Ryerson
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Additional file 3: Table S3. Proportion of ILD diagnoses for incident, prevalent and overall cases.
Engineering the dissipation of crystalline micromechanical resonators
Creators: name: Romero, Erick
name: Valenzuela, Victor M.
name: Kermany, Atieh R.
name: Sementilli, Leo
name: Iacopi, Francesca
name: Bowen, Warwick P.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applied Physics (physics.app-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: High quality micro- and nano-mechanical resonators are widely used in sensing, communications and timing, and have future applications in quantum technologies and fundamental studies of quantum physics. Crystalline thin-films are particularly attractive for such resonators due to their prospects for high quality, intrinsic stress and yield strength, and low dissipation. However, when grown on a silicon substrate, interfacial defects arising from lattice mismatch with the substrate have been postulated to introduce additional dissipation. Here, we develop a new backside etching process for single crystal silicon carbide microresonators that allows us to quantitatively verify this prediction. By engineering the geometry of the resonators and removing the defective interfacial layer, we achieve quality factors exceeding a million in silicon carbide trampoline resonators at room temperature, a factor of five higher than without the removal of the interfacial defect layer. We predict that similar devices fabricated from ultrahigh purity silicon carbide and leveraging its high yield strength, could enable room temperature quality factors as high as $6\times10^9$
description: 9 pages 5 figures
Exact solution at integrable coupling of a model for the Josephson effect between small metallic grains
Creators: name: Links, J.
name: Zhou, H. -Q.
name: McKenzie, R. H.
name: Gould, M. D.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: A model is introduced for two reduced BCS systems which are coupled through the transfer of Cooper pairs between the systems. The model may thus be used in the analysis of the Josephson effect arising from pair tunneling between two strongly coupled small metallic grains. At a particular coupling strength the model is integrable and explicit results are derived for the energy spectrum, conserved operators, integrals of motion, and wave function scalar products. It is also shown that form factors can be obtained for the calculation of correlation functions. Further, a connection with perturbed conformal field theory is made.
description: 12 pages, latex, no figures
MOESM1 of The community-based prevention of diabetes (ComPoD) study: a randomised, waiting list controlled trial of a voluntary sector-led diabetes prevention programme
Creators: name: Smith, Jane
name: Greaves, Colin
name: Thompson, Janice
name: Taylor, Rod
name: Jones, Matthew
name: Armstrong, Rosy
name: Moorlock, Sarah
name: Griffin, Ann
name: Solomon-Moore, Emma
name: Biddle, Michele
name: Price, Lisa
name: Abraham, Charles
Publisher: name: figshare
Year: 2019
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1. CONSORT checklist.
Procampylaspis Bonnier 1896
Creators: name: Petrescu, Iorgu
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Cumacea
Nannastacidae
Procampylaspis

description: Genus Procampylaspis Bonnier, 1896
 Diagnosis. (After Petrescu, 2006). Carapace vaulted; mandible with acute pars molaris; maxilliped 2 dactylus with multiple teeth called “rake-like” (Petrescu, 2006); pereopod 1 with ischium as long as merus.
 Remarks. Four species, including two new species, are added to the three species previously known from the area.
description: Published as part of Petrescu, Iorgu, 2018, On the Family Nannastacidae (Crustacea, Cumacea) from the Australian Museum Collection, pp. 1-111 in Records of the Australian Museum 70 (1) on page 38, DOI: 10.3853/j.2201-4349.70.2018.1645, http://zenodo.org/record/5236860
Density functional theory for collisionless plasmas -- equivalence of fluid and kinetic approaches
Creators: name: Manfredi, Giovanni
Publisher: name: arXiv
Year: 2019
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Density functional theory (DFT) is a powerful theoretical tool widely used in such diverse fields as computational condensed matter physics, atomic physics, and quantum chemistry. DFT establishes that a system of $N$ interacting electrons can be described uniquely by its single-particle density $n(\boldsymbol{r})$, instead of the $N$-body wave function, yielding an enormous gain in terms of computational speed and memory storage space. Here, we use time-dependent DFT to show that a classical collisionless plasma can always, in principle, be described by a set of fluid equations for the single-particle density and current. The results of DFT guarantee that an exact closure relation, fully reproducing the Vlasov dynamics, necessarily exists, although it may be complicated (nonlocal in space and time, for instance) and difficult to obtain in practice. This goes against the common wisdom in plasma physics that the Vlasov and fluid descriptions are mutually incompatible, with the latter inevitably missing some "purely kinetic" effects.
description: To appear in the Special Issue "The many facets of the Vlasov equation", published by the Journal of Plasma Physics, from the Vlasovia 2019 conference, Strasbourg, France, July 2019
Evolving networks with distance preferences
Creators: name: Jost, J.
name: Joy, M. P.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We study evolving networks where new nodes when attached to the network form links with other nodes of preferred distances. A particular case is where always the shortest distances are selected (``make friends with the friends of your present friends''). We present simulation results for network parameters like the first eigenvalue of the graph Laplacian (synchronizability), clustering coefficients, average distances, and degree distributions for different distance preferences and compare with the parameter values for random and scale free networks. We find that for the shortest distance rule we obtain a power law degree distribution as in scale free networks, while the other parameters are significantly different, especially the clustering coefficient.
description: REVTEX Format, 6 Pages, 6 Figures, 1 Table; References added and Revised
The micromechanical testing of Ni based superalloys
Creators: name: Adande, Suki
Publisher: name: Imperial College London
Year: 2018

description: Ni superalloys are engineered material systems, where each microstructural feature conveys specific strengthening mechanisms. This project establishes experimental techniques which focus on understanding deformation in Ni superalloys; building upwards from single crystal CMSX-4, to polycrystalline FGH96, to carburised CMSX-4 & 10. The project combines micromechanical testing and material characterisation with the aim of extracting engineering properties, to help further advance the micromechanics field and aid in the development of new alloys. Micropillar compression experiments were used in this study and enable the analysis of deformation at characteristic strain(s) on the same length scale as the deformation processes. The critical resolved shear stress of pillars fabricated in {001} {011} {111} on single crystal CMSX-4 varied by 380 ± 10 MPa, 420 ± 15 MPa, 460 ± 16 MPa respectively, the resolved shear stress of pillars fabricated on individual grains on a polycrystal0 line sample, with nearly identical areas in the same orientation varies by less than 5% and these results were found to be consistent with literature. The critical resolved shear stress of pillars fabricated on single crystal CMSX-4, with carbide type phases captured on the top surface of the pillars varied by 400 ± 3.4 MPa, 420 ± 6 MPa 450 ± 23 MPa respectively, despite being the same crystal orientation and in similar locations ± 20 µm. The area fraction of the pillars mentioned above were; 5% 17% and 27% respectively. The variation in τcrss was found to be a consequence of the leeching of alloying elements, via the formation of carbide type phases which disrupted the ϒ/ϒ’ microstructure and disrupted the propagation of dislocations. The carbide size, area fraction, number density and shape abnormality were theorised to be proportional to the extent of ϒ/ϒ’ disruption. Transmission electron microscope (TEM), based analysis shows that the carbide type phases orientate themselves at junctions and dislocations tend to agglomerate around the phases at these points.
Zenodo - Why, what and how?
Creators: name: Plomp, Esther
Publisher: name: Zenodo
Year: 2025
Subjects: Zenodo
Open Data
Data repository
FAIR
RDM

description: Presentation about Zenodo for Data Umbrella by Esther Plomp, recorded on 14 February 2025. The video of the presentation is available: Intro to Zenodo (https://youtu.be/eChOfh8t04k).

About Zenodo 

Zenodo (https://zenodo.org) is a general data repository where any research output (data, presentations, research articles, software, and much more!) can be shared and preserved for the long term, increasing their visibility and impact.

Zenodo is derived from Zenodotus, the first librarian of the Ancient Library of Alexandria and father of the first recorded use of metadata.  It was launched in 2013 by CERN, which is The European Organization for Nuclear Research, and it is an intergovernmental organization that operates the largest particle physics laboratory in the world. It was built by researchers to ensure that anyone can join Open Science. The repository welcomes research from all over the world and all disciplines. Zenodo does not impose any requirements on format, size, access restrictions or licence. "Quite literally they wish there to be no reason for researchers not to share!"

The benefits of Zenodo include:- Being accessible: It is free (up to 50 GB per upload)- Helping researchers receive credit by making the research results citable - Providing a Digital Object Identifier (DOI) which is a globally unique persistent identifier for your record and is an important for discovery system to attribute citations correctly- Preserving knowledge- Supporting Open Science and reproducibility principles
Phonon structure in I-V characteristic of MgB$_{2}$ point-contacts
Creators: name: Yanson, I. K.
name: Fisun, V. V.
name: Bobrov, N. L.
name: Naidyuk, Yu. G.
name: Kang, W. N.
name: Choi, Eun-Mi
name: Kim, Hyun-Jung
name: Lee, Sung-Ik
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The search of the phonon structure at the above-gap energies was carried out for $d^{2}V/dI^{2}(V)$ spectra of MgB$_{2}$ point contacts with a normal metal. The two-band model is assumed not only for the gap structure in $dV/dI(V)$-characteristics, but also for phonons in $d^{2}V/dI^{2}(V)$ point-contact spectra, with up to the maximum lattice vibration energy. Since the current is carried mostly by charges of 3D-band, whereas the strong electron-phonon interaction occurs in 2D-band, we observe the phonon peculiarities due to ''proximity'' effect in {\it k}-space, which depends on the variation of interband coupling through the elastic scattering.
description: 6 pages, 4 figures, revtex4, reported in International Conference "Modern Problems in Superconductivity", 9-13 September, Yalta, Ukraine
Procampylaspis bispinosa Ledoyer 1988
Creators: name: Petrescu, Iorgu
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Cumacea
Nannastacidae
Procampylaspis
Procampylaspis bispinosa

description: Procampylaspis bispinosa Ledoyer, 1988
 Procampylaspis bispinosa Ledoyer, 1988: 166.
 Material examined: 1♀, P.90710.
 Distribution. Mozambique Channel, 00'1" S 45.38 '3"E, 3370 m (Ledoyer, 1988) and now fromAustralia: VIC—southwest of Gabo Island, at 210 m depth.
description: Published as part of Petrescu, Iorgu, 2018, On the Family Nannastacidae (Crustacea, Cumacea) from the Australian Museum Collection, pp. 1-111 in Records of the Australian Museum 70 (1) on page 38, DOI: 10.3853/j.2201-4349.70.2018.1645, http://zenodo.org/record/5236860
Additional file 1 of Sedation versus protective stabilization for dental treatment of children with caries and challenging behavior at the dentist (CHOOSE): a study protocol for a non-randomized clinical trial
Creators: name: Da Silva, Gabriela Seabra
name: Anabuki, Anna Alice
name: Karolline Alves Viana
name: Corrêa-Faria, Patricia
name: Mônica Maia Moterane
name: Tedesco, Tamara Kerber
name: Costa, Paulo Sucasas
name: Hosey, Marie Therese
name: Raggio, Daniela Prócida
name: Costa, Luciane Rezende
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. SPIRIT checklist.
Dinitrogen activation of N-triphos transition metal complexes
Creators: name: Apps, Samantha
Publisher: name: Imperial College London
Year: 2019

description: Tripodal phosphine ligands have been widely used in coordination chemistry and catalysis, yet, of the many derivatives reported, the nitrogen-centred tripodal phosphine ligand (N-triphos) has received little attention. However, the unique inclusion of the apical nitrogen centre, with a chemically accessible lone pair, sets N-triphos apart from other ligand systems, leaving room for further exploration of the coordination chemistry and applications of this ligand motif. One particular application with significant implications towards sustainable food production is nitrogen fixation. Replacing the energy intensive Haber-Bosch process for other, more efficient routes towards ammonia formation is a problem that has been addressed by chemists for over 50 years. Such alternatives include the preparation of novel metal-dinitrogen complexes that are able to catalyse the reductive protonation of dinitrogen to form ammonia, under ambient conditions. This thesis therefore explores the use of the N-triphos ligand to develop transition metal dinitrogen complexes that could act as catalysts for ambient N2 fixation. A range of novel molybdenum and cobalt N-triphos dinitrogen complexes were prepared, and the N2 activation and reactivity of these systems were investigated. The denticity of the N-triphos ligand in both cases was dependent on the phosphine substituents i.e. more electron-donating ligands increased the degree of dinitrogen activation but displayed only bidentate coordination behaviour. The phenyl N-triphos ligand provided the most stability in both Mo and Co systems, and these dinitrogen complexes were investigated for further reactivity. The molybdenum complex did not show any N2 functionalisation, but reactivity instead occurred at the apical N-triphos amine, and an unusual alkali-metal mediated rearrangement was observed. In contrast, the cobalt complex showed a high degree of N2 activation, and subsequent dinitrogen functionalisation was achieved by silylation. The cobalt systems show significant potential for future catalytic applications in nitrogen fixation. Novel, nitrogen-centred tripodal N-heterocyclic carbene ligands were also envisioned, as derivatives of the N-triphos ligand with stronger ligand donor properties. The pro-ligand salts were synthesised, but deprotonation to achieve the free carbenes was not achieved, nor was complexation of the tripodal system to group 11 metals.
Covariant Realization of Quantum Spaces as Star Products by Drinfeld Twists
Creators: name: Blohmann, Christian
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Algebra (math.QA)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 81R60; 17B37

description: Covariance of a quantum space with respect to a quantum enveloping algebra ties the deformation of the multiplication of the space algebra to the deformation of the coproduct of the enveloping algebra. Since the deformation of the coproduct is governed by a Drinfeld twist, the same twist naturally defines a covariant star product on the commutative space. However, this product is in general not associative and does not yield the quantum space. It is shown that there are certain Drinfeld twists which realize the associative product of the quantum plane, quantum Euclidean 4-space, and quantum Minkowski space. These twists are unique up to a central 2-coboundary. The appropriate formal deformation of real structures of the quantum spaces is also expressed by these twists.
The prostaglandin D2 pathway in rhinovirus-induced asthma exacerbations
Creators: name: Farne, Hugo Andres
Publisher: name: Imperial College London
Year: 2018

description: Background: Despite currently available treatments, many asthma sufferers continue to experience exacerbations of their disease. This is driven by excess ‘type 2’ inflammation in a large proportion of these individuals. Antiviral interferon responses are also deficient in asthma, possibly as a consequence of excess type 2 inflammation. The CRTH2 receptor is present on cells that are instrumental in promoting type 2 inflammation, and both CRTH2 and its ligand Prostaglandin D2 (PGD2) are upregulated in asthma, making it an attractive target. Trials to date have only shown that in mild asthma and stable disease, when presumably type 2 inflammation is quiescent, CRTH2 antagonism is relatively ineffective. Methods: The effect of the CRTH2 antagonist OC459 on the type 2 inflammation induced by experimental rhinovirus infection in asthma was assessed in the placebo-controlled trial. A parallel mechanistic analysis was conducted to evaluate the effect of OC459 on CRTH2+ cell recruitment and activation to release type 2 cytokines, on antiviral immunity, and to understand the relative importance of PGD2-CRTH2 signalling in the pathophysiology of asthma exacerbations. Results: Rhinovirus infection resulted in type 2 inflammation and associated worsening of asthma symptoms and lung function, which were unaffected by treatment with OC459. PGD2 was not induced by rhinovirus, with little change in CRTH2+ cell numbers in the lungs. Correlations with alternative proposed regulators of type 2 inflammation suggest IL-33 and TSLP are the predominant factors during asthma exacerbations. Antiviral immunity was not altered by OC459. Conclusion: CRTH2 antagonism did not prevent the virally-induced worsening of asthma pathology and symptoms. Mechanistic analyses suggests PGD2-CRTH2 signalling is redundant in the recruitment of type 2 inflammatory cells and induction of type 2 cytokines in response to viral infection. Absent an effect on type 2 inflammation, it was not possible to test the hypothesis that this suppresses antiviral immunity.
The iron line in MCG-6-30-15 from XMM-Newton: evidence for gravitational light-bending?
Creators: name: Fabian, A. C.
name: Vaughan, S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The lack of variability of the broad iron line seen in the Seyfert 1 galaxy MCG-6-30-15 is studied using the EPIC pn data obtained from a 2001 observation of 325 ks, during which the count rate from the source varied by a factor of 5. The spectrum of 80 ks of data from when the source was bright, using the the lowest 10 ks as background, is well fitted over the 3-10 keV band with a simple power-law of photon index Gamma=2.11. The source spectrum can therefore be decomposed into an approximately constant component, containing a strong iron emission line, and a variable power law component. Assuming that the power-law continuum extends down to 0.5 keV enables us to deduce the absorption acting on the nucleus. A simple model involving Galactic absorption and 2 photoelectric edges (at 0.72 and 0.86 keV) is adequate for the EPIC spectrum above 1 keV. It still gives a fair representation of the spectrum at lower energies where absorption lines, UTAs etc are expected. Applying the absorption model to the low flux spectrum enables us to characterize it as reflection-dominated with iron about 3 times Solar. Fitting this model, with an additional power-law continuum, to 32 x 10 ks spectra of the whole observation reveals that Gamma lies mostly between 2 and 2.3 and the normalization of the reflection-dominated component varies by up to 25 per cent. The breadth of the iron line suggests that most of the illumination originates from about 2 gravitational radii. Gravitational light bending will be very strong there, causing the observed continuum to be a strong function of the source height and much of the continuum radiation to return to the disk. Together these effects can explain the otherwise puzzling disconnectedness of the continuum and reflection components of MCG-6-30-15.
The ALPINE-ALMA [CII] survey: Star-formation-driven outflows and circumgalactic enrichment in the early Universe
Creators: name: Ginolfi, M.
name: Jones, G. C.
name: Bethermin, M.
name: Fudamoto, Y.
name: Loiacono, F.
name: Fujimoto, S.
name: Fevre, O. Le
name: Faisst, A.
name: Schaerer, D.
name: Cassata, P.
name: Silverman, J. D.
name: Yan, Lin
name: Capak, P.
name: Bardelli, S.
name: Boquien, M.
name: Carraro, R.
name: Dessauges-Zavadsky, M.
name: Giavalisco, M.
name: Gruppioni, C.
name: Ibar, E.
name: Khusanova, Y.
name: Lemaux, B. C.
name: Maiolino, R.
name: Narayanan, D.
name: Oesch, P.
name: Pozzi, F.
name: Rodighiero, G.
name: Talia, M.
name: Toft, S.
name: Vallini, L.
name: Vergani, D.
name: Zamorani, G.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We study the efficiency of galactic feedback in the early Universe by stacking the [C II] 158 um emission in a large sample of normal star-forming galaxies at 4 < z < 6 from the ALMA Large Program to INvestigate [C II] at Early times (ALPINE) survey. Searching for typical signatures of outflows in the high-velocity tails of the stacked [C II] profile, we observe (i) deviations from a single-component Gaussian model in the combined residuals and (ii) broad emission in the stacked [C II] spectrum, with velocities of |v| 4. From the stacking analysis of the datacubes, we find that the combined [C II] core emission (|v|< 200 km/s) of the higher-SFR galaxies is extended on physical sizes of ~ 30 kpc (diameter scale), well beyond the analogous [C II] core emission of lower-SFR galaxies and the stacked far-infrared continuum. The detection of such extended metal-enriched gas, likely tracing circumgalactic gas enriched by past outflows, corroborates previous similar studies, confirming that baryon cycle and gas exchanges with the circumgalactic medium are at work in normal star-forming galaxies already at early epochs.
description: 16 pages, 10 figures. Accepted for publication in A&A
The spectrum of boundary states in sine-Gordon model with integrable boundary conditions
Creators: name: Bajnok, Z.
name: Palla, L.
name: Takacs, G.
name: Toth, G. Zs.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: The bound state spectrum and the associated reflection factors are determined for the sine-Gordon model with arbitrary integrable boundary condition by closing the bootstrap. Comparing the symmetries of the bound state spectrum with that of the Lagrangian it is shown how one can "derive" the relationship between the UV and IR parameters conjectured earlier.
description: LaTeX2e, 19 pages, 15 eps figures. References updated, note added. Accepted for publication in Nuclear Physics B
Efficient numerical modelling of the ultrasonic scattering from complex surface-breaking defects
Creators: name: Phillips, Richard
Publisher: name: Imperial College London
Year: 2018

description: Ultrasonic testing is routinely used in the nuclear power generation industry to assess the structural integrity of plant components. The regulatory nature of the industry means that ultrasonic inspection procedures require substantiation through experimental trials and semi-analytical simulation, which can be costly and time-consuming. Furthermore, due to the complex defect and component geometries that are commonly encountered in the industry, the generation of evidence that accurately represents real inspections can be challenging. Numerical modelling techniques offer an effective alternative for substantiating inspections as they can accurately simulate the ultrasonic scattering from complex geometries, yet such techniques lead to increased computational cost. Hybrid techniques, which combine both semi-analytical and numerical methods, offer an approach to rapidly simulate an entire ultrasonic inspection whilst maintaining the ability to simulate the scattering from complex defects. However, there is a lack of experimental validation for extant hybrid techniques, particularly for three-dimensional simulations, and they have not been widely applied to the simulation of surface-breaking defect inspections, which are commonly encountered in both manufacturing and in-service inspections. This thesis has extended the functionality of a three dimensional hybrid technique to simulate the inspection of surface-breaking defects. Validation evidence demonstrates that the hybrid model accurately predicts the ultrasonic scattering from a well-characterised reflector. An arbitrary transduction system has been incorporated to the model, enabling the model to be more broadly applied to the simulation of ultrasonic inspections of plant components. Furthermore, validation on a real defect provides a high level of confidence that the model can be used to assess and quantify the performance of inspections where qualification becomes challenging. This work has made a clear step forward in the use of simulation for inspection qualification and further work is required to fully optimise the simulation methodology.
Plant Breeders' Rights Legislation, Enforcement and R&D: Lessons for Developing Countries
Creators: name: Pray, Carl E.
name: Pray, Carl E.
Publisher: name: Unknown
Year: 1992
Subjects: Agricultural Finance
International Development

description: Declining government budgets, pressure from donors and agribusiness firms and the failure of some government seed corporations are encouraging policy makers in a number of less developed countries (LDCs) to privatize plant breeding, seed production and seed distribution. Developed countries are pressing for stronger intellectual property rights such as plant breeders' rights (PBR) and utility patents as a means of encouraging private firms to transfer technology and conduct more research and development (R&D). A number of countries are considering PBR legislation.1 This paper examines the development of PBRs and their impact on private research and technology transfer in the United States, France, the United Kingdom, Argentina and Chile. From their experiences some policy implications for developing countries are derived.
The impact of human immunodeficiency virus-1 viral replicative capacity on infection of human cervical and rectal tissue explants ex vivo
Creators: name: Langat, Robert Kipyegon
Publisher: name: Imperial College London
Year: 2020

description: Characterization of the targets and kinetics of HIV infection within rectal and genital tissues is central to the assessment of novel prevention agents. The ex vivo models available are helpful for studying the initial stages of HIV‐1 infection, such as defining the primary HIV target cells and the factors that influence viral replication kinetics. Five HIV-1 clade C, 1 clade A and 1 clade A/D HIV-1 TF variants were isolated from IAVI Protocol C; a prospective acute infection cohort, and their infection of PBMCs (n=7), rectal (n=59) and endo- and ecto-cervical (n=49) tissue explants were assessed relative to HIV1BaL over 15 days in culture. There was no statistical difference in the rates of replication of the HIV-1 variants relative to HIV-1BaL in endo- and ectocervical tissues with the exception of HIV-1K4791 which replicated significantly higher in ectocervix than endocervix. Interestingly, HIV-1 variants defined as having “high replicative capacity” (RC) replicated to similar rates as those defined as low RC in cervical tissues in these experiments. We observed high levels of inter-donor variation in all tissues tested, however we detected HIV-1 replication in PBMC, rectal and cervical tissues with varied kinetics. HIV-1 variants infected both CD3+Th17 cells as well as non-T cells within rectal and cervical tissues 2 days after infection. The infected non-T cells were large and irregularly shaped; a phenotype consistent with myeloid dendritic or macrophages, and we aim to confirm the identity of these cells using tailored combinations of antibodies in future using existing stored samples. We have successfully transferred and established an explant culture system at KAVI-ICR for studying early events of HIV‐1 transmission in cervical and rectal tissues ex vivo. They are valuable tools to test the efficacy of microbicides in the prevention of HIV‐1 transmission study HIV-1, as well to evaluate HIV-1 vaccine candidates
MOESM1 of Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmonary Fibrosis
Creators: name: J. Fisher
name: M. Kolb
name: M. Algamdi
name: J. Morisset
name: K. Johannson
name: S. Shapera
name: P. Wilcox
name: T. To
name: M. Sadatsafavi
name: H. Manganas
name: N. Khalil
name: N. Hambly
name: A. Halayko
name: A. Gershon
name: C. Fell
name: G. Cox
name: C. Ryerson
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology
subject: Computational Biology

description: Additional file 1: Table S1. Exposures captured in the CAnadian REgistry for Pulmonary Fibrosis.
Additional file 2 of Sedation versus protective stabilization for dental treatment of children with caries and challenging behavior at the dentist (CHOOSE): a study protocol for a non-randomized clinical trial
Creators: name: Da Silva, Gabriela Seabra
name: Anabuki, Anna Alice
name: Karolline Alves Viana
name: Corrêa-Faria, Patricia
name: Mônica Maia Moterane
name: Tedesco, Tamara Kerber
name: Costa, Paulo Sucasas
name: Hosey, Marie Therese
name: Raggio, Daniela Prócida
name: Costa, Luciane Rezende
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. Details of clinical and laboratory procedures.
Cellwise Robust M Regression
Creators: name: Filzmoser, Peter
name: Höppner, Sebastiaan
name: Ortner, Irene
name: Serneels, Sven
name: Verdonck, Tim
Publisher: name: arXiv
Year: 2019
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: The cellwise robust M regression estimator is introduced as the first estimator of its kind that intrinsically yields both a map of cellwise outliers consistent with the linear model, and a vector of regression coefficients that is robust against vertical outliers and leverage points. As a by-product, the method yields a weighted and imputed data set that contains estimates of what the values in cellwise outliers would need to amount to if they had fit the model. The method is illustrated to be equally robust as its casewise counterpart, MM regression. The cellwise regression method discards less information than any casewise robust estimator. Therefore, predictive power can be expected to be at least as good as casewise alternatives. These results are corroborated in a simulation study. Moreover, while the simulations show that predictive performance is at least on par with casewise methods if not better, an application to a data set consisting of compositions of Swiss nutrients, shows that in individual cases, CRM can achieve a significantly higher predictive accuracy compared to MM regression.
MOESM1 of Nature and consequences of interactions between Salmonella enterica serovar Dublin and host cells in cattle
Creators: name: Prerna Vohra
name: Vrettou, Christina
name: Hope, Jayne
name: Hopkins, John
name: Stevens, Mark
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1. Validation of pFPV25.1 for detection of Salmonella-infected bovine cells. Several in vitro and in vivo tests were performed to assess the suitability of pFPV25.1 for detection of Salmonella-infected cells. (A–C) Firstly, bovine peripheral blood-derived macrophages were infected in vitro with SD3246-GFP at a MOI of 100 and infected cells were identified using either the constitutive GFP-expression from pFPV25.1 or by staining with anti-Salmonella LPS. (A) While the majority of GFP+ (infected) cells were also LPS+, a proportion of infected cells were incorrectly identified by anti-LPS staining. (B) The GFP signal from infected cells was sensitive and specific. (C) Detection of infected cells by anti-LPS staining was less specific than GFP. (D) Following this, the effect of presence of pFPV25.1 on bacterial invasion of peripheral blood-derived macrophages was determined in vitro and it was found that SD3246-GFP was less invasive than wild-typec SD3246 nalR. (E) This phenotype was confirmed in vivo using the bovine ligated ileal loop model. While SD3246-GFP was less invasive than SD3246 nalR after 10 h of infection, the total bacterial numbers recovered were similar from loops inoculated with both strains. (F) Following oral challenge of calves with SD3246-GFP, the stability of pFPV25.1 was confirmed to inform the accuracy of identifying Salmonella-infected cells. It was found that pFPV25.1 was stably maintained within intracellular bacteria recovered from tissues of these calves 48 h post-infection, even in the absence of ampicillin selection, providing confidence that the GFP signal was used to accurately detect infected bovine cells. (G) Lastly, the effect of presence of pFPV25.1 on clinical signs was assessed and it was found that the pyrexia induced in SD3246-GFP-challenged calves was the same as that expected during wild-type S. Dublin infections, confirming that virulence of SD3246-GFP had not been adversely affected.
Realistic indirect spin-interactions between magnetic impurities on a metallic Pb(110) surface
Creators: name: Rébola, Alejandro
name: Lobos, Alejandro M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Motivated by recent experiments, here we study the indirect interactions between magnetic impurities deposited on top of a clean Pb(110) surface induced by the underlying conduction electrons. Our approach makes use of \textit{ab initio} calculations to characterize the clean Pb(110) surface and avoids self-consistency, a feature that greatly reduces the computational cost. In combination with 2$^{\text{nd}}$ order perturbation theory in the microscopic \textit{s-d} exchange parameter $J_{K}$ between a magnetic adatom and the conduction electrons, we are able to systematically derive the Ruderman-Kittel-Kasuya-Yosida (RKKY), the Dzyaloshinskii-Moriya (DM) and the anisotropic tensor interactions emerging at the Pb(110) surface between magnetic impurities. The only adjustable parameter is $J_{K}$, which is fitted to reproduce the experiments. Our results show important anisotropy effects arising both from the rectangular geometry of the (110) unit cell, and from the strong Rashba spin-orbit interaction due to the broken inversion symmetry at the Pb(110) surface. In addition to Pb(110), the characterization of the indirect spin interactions described here could be extended to other realistic metallic surfaces for weakly-coupled impurities, and would enable to fabricate atomic-size nanostructures with engineered interactions and on-demand magnetic properties, anticipating useful applications in nanotechnology.
description: 10 pages, 5 figures
Procampylaspis sordida Hale 1945
Creators: name: Petrescu, Iorgu
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Cumacea
Nannastacidae
Procampylaspis
Procampylaspis sordida

description: Procampylaspis sordida Hale, 1945
 Procampylaspis sordida Hale, 1945: 215. Stoddart & Lowry, 2003: 417.
 Material examined: 2♀♀, P.90717; 1♀, P.64649; 1♀, P.90718; 1♂, P.90719; 1♀, MGAB CUM 1681; 1♂, P.90788; 1♀, P.90789; 1♀, 1♂, P.90790; 1♀, P.65342; 1♀, P.90791.
 Distribution. Australia: NSW, 60–100 m (Hale, 1945). Now reported from Tasman Sea—Lord Howe Rise, at 1500 m; NSW—east of Broken Bay, northeast of Coffs Harbour, of Eden, and of Port Jackson, at 75–1015 m; TAS—east of Flinders Island, at 280–350 m; VIC—Bass Strait, at 118–125 m; and WA—Dampier Archipelago, at 14 m depth.
description: Published as part of Petrescu, Iorgu, 2018, On the Family Nannastacidae (Crustacea, Cumacea) from the Australian Museum Collection, pp. 1-111 in Records of the Australian Museum 70 (1) on page 39, DOI: 10.3853/j.2201-4349.70.2018.1645, http://zenodo.org/record/5236860
Minnesota Agricultural Economist No. 665
Creators: name: Sundquist, W. Burt
name: Hammond, Jerome W.
name: Sundquist, W. Burt
name: Hammond, Jerome W.
Publisher: name: Unknown
Year: 1991
Subjects: Agricultural and Food Policy

description: "The 1990 Farm Bill: Its Core Provisions and Expected Effects" and "Upper Midwest Challenges to the Federal Milk Marketing Order Program"
Minnesota Agricultural Economist No. 666
Creators: name: Kinsey, Jean D.
name: Senauer, Benjamin
name: Kinsey, Jean D.
name: Senauer, Benjamin
Publisher: name: Unknown
Year: 1991
Subjects: Agricultural and Food Policy
Food Consumption/Nutrition/Food Safety

description: "Trends and Traditions in the American Diet: Implications for Agriculture" and "Food Problems of the Poor"
The role of small RNA in parasite-host communication during Trichinella spiralis infection
Creators: name: Taylor, Peter
Publisher: name: Imperial College London
Year: 2020

description: The parasitic nematode Trichinella spiralis offers a bizarre and compelling example of host manipulation. Occupying both an enteric and intracellular muscle cell niche, the worm appears to hijack the host’s innate cellular biological processes to bring about morphological shifts in the muscle cell which it inhabits, creating a more hospitable environment for the its own development. (1, 2). The molecular mechanisms underpinning this phenomenon are largely unknown. Recently there has been much interest in extracellular small RNAs secreted within exosomesextracellular vesicles, including in parasitic nematode infection (3). Here I investigate whether T. spiralis secretes small RNAs as part of its pathogenesis. I profiled small RNAs secreted by T. spiralis from both its adult (enteric) and muscle larval stages of the life cycle. My data suggest demonstrated that T. spiralis is indeed secretingsecretes miRNA (Chapters 3 and 4). Intriguingly the majority of small RNAs secreted by muscle stage larvae are not encapsulated within exosomesextracellular vesicles, consistent with its intracellular niche and implicating a novel secretory mechanism. Small RNAs enriched within the secreted fraction include those with homology to host miRNAs known to play a crucial role in muscle development and disease, such as miR-31 (Chapter 4). To test the role of secreted miRNAs in infection I generated an inducible expression system in the muscle cell line C2C12 (Chapter 5). Induction of exogenous miRNA expression and subsequent sequencing suggests that T. spiralis miR-31 is able to target host mRNA, with genes targeted including genes linked to muscular dystrophic disease (Chapter 6). I then describe further work which should be performed to solidify and expand upon the findings of this thesis (Chapter 7).
Scherocumella Watling 1991
Creators: name: Petrescu, Iorgu
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Cumacea
Nannastacidae
Scherocumella

description: Key to species of Scherocumella from Australian waters
1 Carapace, pereon and pleon with dorsal tubercles.................................................................... 2
—— Carapace, pereon and pleon without dorsal tubercles............................................................... 4
2 First 4 pleonites with tubercles.................................................................................................. 3
 —— First 2 pleonites with dorsal tubercles........................................................ S. vieta (Hale, 1945)
 3 Pleonites 3–6 with dorsal carina.............................................................. S. weinbergae sp. nov.
 —— Pleonites 3–6 without dorsal carina........................................................ S. clavata (Hale, 1945)
4 Peduncle of uropod longer than pleonite 6................................................................................ 5
—— Peduncle of uropod shorter than pleonite 6............................................................................... 7
 5 Peduncle of uropod more than twice as long as pleonite 6................ S. nasuta (Zimmer, 1914)
—— Peduncle of uropod less than twice as long as pleonite 6......................................................... 6
 6 Peduncle of uropod 1.3 pleonite 6 length............................................... S. sheardi (Hale, 1945)
 —— Peduncle of uropod 1.12 pleonite 6 length................................................. S. wittmanni sp. nov.
 7 Carapace, length/height: 1.5................................................................. S. nichollsi (Hale, 1949)
 —— Carapace, length/height: 2........................................................................... S. lima (Hale, 1936)
description: Published as part of Petrescu, Iorgu, 2018, On the Family Nannastacidae (Crustacea, Cumacea) from the Australian Museum Collection, pp. 1-111 in Records of the Australian Museum 70 (1) on page 40, DOI: 10.3853/j.2201-4349.70.2018.1645, http://zenodo.org/record/5236860
Topology of the ground state of two interacting Bose-Einstein condensates
Creators: name: Riboli, Francesco
name: Modugno, Michele
Publisher: name: arXiv
Year: 2002
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We investigate the spatial patterns of the ground state of two interacting Bose-Einstein condensates. We consider the general case of two different atomic species (with different mass and in different hyperfine states) trapped in a magnetic potential whose eigenaxes can be tilted with respect to the vertical direction, giving rise to a non trivial gravitational sag. Despite the complicated geometry, we show that within the Thomas-Fermi approximations and upon appropriate coordinate transformations, the equations for the density distributions can be put in a very simple form. Starting from this expressions we give explicit rules to classify the different spatial topologies which can be produced, and we discuss how the behavior of the system is influenced by the inter-atomic scattering length. We also compare explicit examples with the full numeric Gross-Pitaevskii calculation.
description: RevTex4, 8 pages, 7 figures