cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Dose tracking software and optimisation process: the experience in Trieste with Dose Watch
Creators: name: Quaia, Emilio
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 9 - Development of criteria for safe imaging procedures
subject: Action 8 - EuroSafe Imaging Stars network and data collection
subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)
subject: Action 10 - EuroSafe Imaging Stars
subject: Action 5 - Performance indicators for radiation protection management

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: The current Italian law on radiation protection forces continuous assessment of patient’s dose and development of programs to improve diagnostic exams, especially for computed tomography (CT) and angiography. The effectiveness of these programs is...
Effects of spin-orbit coupling and spatial symmetries on the Josephson current in SNS junctions
Creators: name: Rasmussen, Asbjørn
name: Danon, Jeroen
name: Suominen, Henri
name: Nichele, Fabrizio
name: Kjaergaard, Morten
name: Flensberg, Karsten
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present an analysis of the symmetries of the interference pattern of critical currents through a two-dimensional superconductor-semiconductor-superconductor junction, taking into account Rashba and Dresselhaus spin-orbit interaction, an arbitrarily oriented magnetic field, disorder, and structural asymmetries. We relate the symmetries of the pattern to the absence or presence of symmetries in the Hamiltonian, which provides a qualitative connection between easily measurable quantities and the spin-orbit coupling and other symmetries of the junction. We support our analysis with numerical calculations of the Josephson current based on a perturbative expansion up to eighth order in tunnel coupling between the normal region and the superconductors.
description: 6 pages, 3 figures; 5 pages supplementary
A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases
Creators: name: Vincent, Benjamin G.
name: Dowe, Thomas
name: Wilkes, Edmund H.
name: Bixby, Lisa
name: Maniati, Eleni
name: Balkwill, Frances R.
name: Lockley, Michelle
name: Serody, Jonathan S.
name: Pearce, Oliver
name: Montfort, Anne
name: Chakravarty, Probir
name: Böhm, Steffen
name: Topping, Joanne
name: Capasso, Melania
name: Cutillas, Pedro R.
name: Thompson, Richard
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: In high-grade serous ovarian cancer (HGSOC), higher densities of both B cells and the CD8 + T-cell infiltrate were associated with a better prognosis. However, the precise role of B cells in the antitumor response remains unknown. As peritoneal metastases are often responsible for relapse, our aim was to characterize the role of B cells in the antitumor immune response in HGSOC metastases. Unmatched pre and post-chemotherapy HGSOC metastases were studied. B-cell localization was assessed by immunostaining. Their cytokines and chemokines were measured by a multiplex assay, and their phenotype was assessed by flow cytometry. Further in vitro and in vivo assays highlighted the role of B cells and plasma cell IgGs in the development of cytotoxic responses and dendritic cell activation. B cells mainly infiltrated lymphoid structures in the stroma of HGSOC metastases. There was a strong B-cell memory response directed at a restricted repertoire of antigens and production of tumor-specific IgGs by plasma cells. These responses were enhanced by chemotherapy. Interestingly, transcript levels of CD20 correlated with markers of immune cytolytic responses and immune complexes with tumor-derived IgGs stimulated the expression of the costimulatory molecule CD86 on antigen-presenting cells. A positive role for B cells in the antitumor response was also supported by B-cell depletion in a syngeneic mouse model of peritoneal metastasis. Our data showed that B cells infiltrating HGSOC omental metastases support the development of an antitumor response. Clin Cancer Res; 1-13. ©2016 AACR.
Simulation-based multi-objective optimization of side-hull arrangement applied to an inverted-bow trimaran ship at cruise and sprint speeds
Creators: name: Nazemian, Amin
name: Ghadimi, Parviz
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Numerical optimization of an inverted-bow trimaran is carried out through three simulation-based design (SBD) frameworks. Different positions of the trimaran’s side hull are investigated based on a computational fluid dynamics solver using the non-dominated sorting genetic algorithm-III (NSGA-III), simultaneous hybrid exploration that is robust, progressive and adaptive (SHERPA) and response surface (RS) multi-objective optimization for resistance at cruise and sprint speeds. The aims are to create and develop a convenient tool for optimization and investigate the appropriate position of the side hull. An automated, low-cost optimization platform is achieved that can be implemented in other maritime projects. A 10.5% drag reduction for cruise speed and 6.6% reduction for sprint are obtained, corresponding to lower longitudinal and large transversal distances of the side hull. SHERPA and NSGA-III produce the same results, but SHERPA is 2.5 times faster than NSGA-III. RS obtains less desirable results, but in the lowest central processing unit time.
title: Lumbar spine Xray - Computer says No!
Creators: name: Al-Nasiri, Marwan
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 10 - Improved communication and collaboration of health professionals in radiation protection
subject: Action 6 - Education and training in medical radiation protection
subject: Action 1 - Clinical decision support, clinical imaging guidelines
subject: Action 1 - Guidelines, implementation policies, and Clinical Decision Support (ESR iGuide)
subject: Action 8 - Radiation protection training and learning material
subject: Action 13 - Stakeholder engagement and collaboration

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: The National Institute of Health and Care Excellence (NICE) guidance and The Royal College of Radiologists iRefer referral guidelines advise against Lumbar spine X-ray in the management of non-specific low back pain. 1,2 iRefer limits the indication...
Stress-based structural topology optimization for design-dependent self-weight loads problems using the BESO method
Creators: name: Garcez, Gisele L.
name: Pavanello, Renato
name: Picelli, Renato
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: This article aims to propose an approach to the stress-based topology optimization of continuous elastic bi-dimensional structures subjected to design-dependent self-weight loads using the Bi-directional Evolutionary Structural Optimization (BESO) method. Topology optimization is developed through the minimization of P-norm von Mises stress while satisfying a volume constraint. To implement the algorithm, a consistent sensitivity analysis including design-dependent loads has been developed by the adjoint method. A series of tests has been performed to explore and validate the method through three numerical examples: an L-bracket; a doubly supported beam with one pre-existing crack notch; and a cantilever beam. Comparison between traditional compliance minimization and stress minimization analyses, including design-dependent self-weight loads, shows that the method is an effective way to reduce the maximum stress.
Body Composition as a Predictor of Toxicity in Patients Receiving Anthracycline and Taxane–Based Chemotherapy for Early-Stage Breast Cancer
Creators: name: Williams, Grant R.
name: Popuri, Karteek
name: Muss, Hyman B.
name: Weinberg, Marc
name: Choi, Seul Ki
name: Nyrop, Kirsten A.
name: Shachar, Shlomit Strulov
name: Deal, Allison M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Poor body composition metrics (BCM) are associated with inferior cancer outcomes; however, in early breast cancer (EBC) there is a paucity of evidence regarding BCM’s impact on toxicities. This study investigates associations between BCM and treatment-related toxicity in EBC patients receiving anthracyclines-taxane based chemotherapy.
The redshift evolution of escape fraction of hydrogen ionizing photons from galaxies
Creators: name: Khaire, Vikram
name: Srianand, Raghunathan
name: Choudhury, Tirthankar Roy
name: Gaikwad, Prakash
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Using our cosmological radiative transfer code, we study the implications of the updated QSO emissivity and star formation history for the escape fraction (f_esc) of hydrogen ionizing photons from galaxies. We estimate the f_esc that is required to reionize the Universe and to maintain the ionization state of the intergalactic medium in the post-reionization era. At z>5.5, we show that a constant f_esc of 0.14 to 0.22 is sufficient to reionize the Universe. At z<3.5, consistent with various observations, we find that f_esc can have values from 0 to 0.05. However, a steep rise in f_esc, of at least a factor of ~3, is required between z=3.5 to 5.5. It results from a rapidly decreasing QSO emissivity at z>3 together with a nearly constant measured H I photoionization rates at 34. In addition, a simple extrapolation of the contribution of such QSOs to high-z suggests that QSOs alone can reionize the Universe. This implies, at z>3.5, that either the properties of galaxies should evolve rapidly to increase the f_esc or most of the low-mass galaxies should host massive black holes and sustain accretion over a prolonged period. These results motivate a careful investigation of theoretical predictions of these alternate scenarios that can be distinguished using future observations. Moreover, it is also very important to revisit the measurements of H I photoionization rates that are crucial to the analysis presented here.
description: Accepted for publication in MNRAS. 13 Pages, 7 figures
title: The International Society of Radiology as an umbrella for continental and regional radiation protection campaigns
Creators: name: Lau, Lawrence
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 12 - Cooperation with international radiation protection initiatives and other stakeholders including IAEA, WHO, ICRP, HERCA, European Commission
subject: Action 13 - Stakeholder engagement and collaboration

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: A Framework for Radiation Protection Measures, Strategies, and Actions (1) Successful implementation of patient safety and radiation protection actions in practice hinges on radiologist support, leadership, participation, and teamwork with other...
Breast Cancer Disparities at Home and Abroad: A Review of the Challenges and Opportunities for System-Level Change
Creators: name: Reeder-Hayes, Katherine E.
name: Anderson, Benjamin O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Sizeable disparities exist in breast cancer outcomes, both between Black and White patients in the United States, and between patients in the US and other high-income countries compared to low- and middle-income countries (LMICs). In both settings, health system factors are key drivers of disparities. In the US, Black women are more likely to die of breast cancer than Whites, and have poorer outcomes even among patients with similar stage and tumor subtype. Over-representation of higher-risk “triple negative” breast cancers contributes to breast cancer mortality in Black women; however, the greatest survival disparities occur within the good-prognosis hormone-receptor positive (HR+) subtypes. Disparities in access to treatment within the complex US health system may be responsible for a substantial portion of these differences in survival. In LMICs, breast cancer mortality rates are substantially higher than in the US, while incidence continues to rise. This mortality burden is largely attributable to health system factors, including late-stage presentation at diagnosis and lack of availability of systemic therapy. This article will review the existing evidence for how health-system factors in the United States contribute to breast cancer disparities, discuss methods for studying the relationship of health system factors to racial disparities, and provide examples of health system interventions that show promise for mitigating breast cancer disparities. We will then review evidence of global breast cancer disparities in low and middle income countries, the treatment factors that contribute to these disparities, and actions being taken to combat breast cancer disparities around the world.
title: João Ferreira da Maia
Creators: name: Nicolau, Mariana
name: Osório da Silva, Sandra
Publisher: name: CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa
Year: 2022

description: Entrada biográfica sobre João Ferreira da Maia, na plataforma eViterbo
description: Nicolau, Mariana. Silva, Sandra Osório da. 2022. João Ferreira da Maia in eViterbo. CHAM, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa. eISBN: 978-989-8492-77-7
title: High Pitch Imaging of Paranasal Sinus CT Examinations: Image Quality and Radiation Dose
Creators: name: Oguz, Kader
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: High Pitch Imaging has been used mainly for cardiac imaging because of its high temporal resolution. As some angles of scanned object are not covered during scanning it could decrease the radiation dose of examination. In this study we aimed to...
Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials
Creators: name: Elg, Steven A.
name: Mai, Phuong L.
name: Alberts, David
name: Welch, William
name: Fabian, Carol J.
name: Daly, Mary B.
name: Schorge, John O.
name: Rodriguez, Gustavo
name: Horowitz, Ira
name: Davidson, Susan A.
name: Brewster, Wendy R.
name: Nayfield, Susan
name: Isaacs, Claudine
name: Horick, Nora K.
name: Finkelstein, Dianne M.
name: Edwards, Robert
name: Walker, Joan
name: Kasten, Carol H.
name: Buys, Saundra S.
name: Greene, Mark H.
name: Boggess, John
name: Rutherford, Thomas
name: Lu, Karen H.
name: Drescher, Charles W.
name: Piedmonte, Marion
name: Sluss, Patrick M.
name: Armstrong, Deborah
name: Berchuck, Andrew
name: Brown, Powel
name: Wakeley, Katie
name: Skates, Steven J.
name: Partridge, Edward
name: O'Malley, David M.
name: Phillips, Kelly-Anne
name: Sherman, Mark
name: Minasian, Lori
name: Domchek, Susan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Purpose: Women at familial/genetic ovarian cancer risk often undergo screening despite unproven efficacy. Research suggests each woman has her own CA125 baseline; significant increases above this level may identify cancers earlier than standard 6- to 12-monthly CA125 > 35 U/mL. Experimental Design: Data from prospective Cancer Genetics Network and Gynecologic Oncology Group trials, which screened 3,692 women (13,080 woman-screening years) with a strong breast/ovarian cancer family history or BRCA1/2 mutations, were combined to assess a novel screening strategy. Specifically, serum CA125 q3 months, evaluated using a risk of ovarian cancer algorithm (ROCA), detected significant increases above each subject's baseline, which triggered transvaginal ultrasound. Specificity and positive predictive value (PPV) were compared with levels derived from general population screening (specificity 90%, PPV 10%), and stage-at-detection was compared with historical high-risk controls. Results: Specificity for ultrasound referral was 92% versus 90% ( P = 0.0001), and PPV was 4.6% versus 10% ( P > 0.10). Eighteen of 19 malignant ovarian neoplasms [prevalent = 4, incident = 6, risk-reducing salpingo-oophorectomy (RRSO) = 9] were detected via screening or RRSO. Among incident cases (which best reflect long-term screening performance), three of six invasive cancers were early-stage (I/II; 50% vs. 10% historical BRCA1 controls; P = 0.016). Six of nine RRSO-related cases were stage I. ROCA flagged three of six (50%) incident cases before CA125 exceeded 35 U/mL. Eight of nine patients with stages 0/I/II ovarian cancer were alive at last follow-up (median 6 years). Conclusions: For screened women at familial/genetic ovarian cancer risk, ROCA q3 months had better early-stage sensitivity at high specificity, and low yet possibly acceptable PPV compared with CA125 > 35 U/mL q6/q12 months, warranting further larger cohort evaluation. Clin Cancer Res; 23(14); 3628-37. ©2017 AACR .
title: Patient dose management in diagnostic radiology: experience of the IAEA
Creators: name: Vassileva, Jenia
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 6 - Education and training in medical radiation protection
subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)
subject: Action 8 - Radiation protection training and learning material

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: The statutory role of the International Atomic Energy Agency (IAEA) is to establish or adopt standards of safety for protection of health and minimization of danger to life and to provide for the application of these standards. The current...
title: IAEA activities in support to quality in X-ray imaging
Creators: name: Delis, Harry
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 4 - Quality of radiological equipment
subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)
subject: Action 3 - Image quality assessment based on clinical indications

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: The usefulness of diagnostic imaging has been well-established for more than one century. However, the quality of the services provided has been always taken for granted. Comprehensivequality systems are essential to ensuresafe and efficient...
Efficacy of Neoadjuvant Carboplatin plus Docetaxel in Triple-Negative Breast Cancer: Combined Analysis of Two Cohorts
Creators: name: Picornell, Antoni C.
name: Cortes, Javier
name: Sharma, Priyanka
name: Palomero, María Isabel
name: Gonzalez-Rivera, Milagros
name: Amin, Amanda L.
name: Mammen, Joshua M.V.
name: Morales, Denisse Bretel
name: García-Saenz, Jose Angel
name: Massarrah, Tatiana
name: Del Monte-Millán, Maria
name: Ward, Claire
name: Wagner, Jamie L.
name: Jerez-Gilarranz, Yolanda
name: Klemp, Jennifer R.
name: López-Tarruella, Sara
name: Connor, Carol S.
name: Prat, Aleix
name: Gómez, Henry L.
name: Heldstab, Jaimie
name: Jensen, Roy A.
name: McGinness, Marilee K.
name: Fabian, Carol J.
name: Martin, Miguel
name: Kimler, Bruce F.
name: González Del Val, Ricardo
name: Márquez-Rodas, Iván
name: Pelaez-Lorenzo, Beatriz
name: Khan, Qamar J.
name: Barnadas, Augusti
name: Rivera, Hugo Fuentes
name: Moreno, Fernando
name: Perou, Charles M.
name: Godwin, Andrew K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Recent studies demonstrate that addition of neoadjuvant (NA) carboplatin (Cb) to anthracycline/taxane chemotherapy improves pathological complete response (pCR) in triple negative breast cancer (TNBC). Effectiveness of anthracycline-free, platinum combinations in TNBC is not well known. Here we report efficacy of NA carboplatin + docetaxel (CbD) in TNBC.
title: Image Wisely® - The US Campaign for Radiation Safety in Adult Medical Imaging
Creators: name: Butler, Priscilla
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 12 - Cooperation with international radiation protection initiatives and other stakeholders including IAEA, WHO, ICRP, HERCA, European Commission
subject: Action 10 - Improved communication and collaboration of health professionals in radiation protection
subject: Action 6 - Education and training in medical radiation protection
subject: Action 8 - Radiation protection training and learning material
subject: Action 13 - Stakeholder engagement and collaboration

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: A 2009 report by the National Council of Radiation Protection and Measurements (“ Ionizing Radiation Exposure of the Population of the United States ”) [1] showed that almost half of the annual radiation exposure to the US population was from...
title: EPF Patient Empowerment Campaign
Creators: name: Bedlington, Nicola
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Health policy and practice
subject: Plain radiographic studies
subject: Management
subject: Action 12 - Information for and communication with patients
subject: Action 11 - Improved patient communication
subject: Education and training

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: Patient empowerment is a process that helps people gain control over their own lives and increases their capacity to act on issues they themselves define as important. Empowerment has both an individual and a collective dimension: at individual...
Skeletal Muscle Measures as Predictors of Toxicity, Hospitalization, and Survival in Patients with Metastatic Breast Cancer Receiving Taxane-Based Chemotherapy
Creators: name: Nyrop, Kirsten A.
name: Williams, Grant R.
name: Deal, Allison M.
name: Weinberg, Marc
name: Benbow, Julia M.
name: Muss, Hyman B.
name: Shachar, Shlomit Strulov
name: Nishijima, Tomohiro F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Severe skeletal muscle (SM) loss (sarcopenia), is associated with poor cancer outcomes including reduced survival and increased toxicity. This study investigates SM measures in metastatic breast cancer (MBC) patients receiving first line taxane-based chemotherapy and evaluates associations with treatment toxicity and other outcomes.
title: Image Gently and EuroSafe Imaging: A Shared Voice
Creators: name: Frush, Donald
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 11 - Improved patient communication
subject: Action 10 - Improved communication and collaboration of health professionals in radiation protection
subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)
subject: Action 13 - Stakeholder engagement and collaboration
subject: Action 12 - Information for and communication with patients

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: The Need Continues: Diagnostic imaging accounts for a relatively large percentage of the average total annual exposure per capita in the United States (US) to ionizing radiation [1]. There are justifiable concerns over appropriate use as well as...
Anomalous magnetic response of a quasi-periodic mesoscopic ring in presence of Rashba and Dresselhaus spin-orbit interactions
Creators: name: Patra, Moumita
name: Maiti, Santanu K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate the properties of persistent charge current driven by magnetic flux in a quasi-periodic mesoscopic Fibonacci ring with Rashba and Dresselhaus spin-orbit interactions. Within a tight-binding framework we work out individual state currents together with net current based on second-quantized approach. A significant enhancement of current is observed in presence of spin-orbit coupling and sometimes it becomes orders of magnitude higher compared to the spin-orbit interaction free Fibonacci ring. We also establish a scaling relation of persistent current with ring size, associated with the Fibonacci generation, from which one can directly estimate current for any arbitrary flux, even in presence of spin-orbit interaction, without doing numerical simulation. The present analysis indeed gives a unique opportunity of determining persistent current and has not been discussed so far.
description: 10 pages, 16 figures (Accepted for Publication in: The European Physical Journal B-Condensed Matter and Complex Systems)
Epidemiological, clinical and immunological characteristics of paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection (PIMS-TS) in children
Creators: name: Hoste, Levi
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medical Sciences
subject: Organisms
subject: Diseases
subject: Medicine and Health Sciences
subject: Medical Immunology
subject: Medical Specialties
subject: Virus Diseases
subject: Pediatrics
subject: Viruses
subject: Immune System Diseases
subject: children
subject: COVID-19
subject: hyperinflammation
subject: Kawasaki disease
subject: MIS-C
subject: pediatrics
subject: PIMS-TS
subject: SARS-CoV-2

description: Systematic review protocol
UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models
Creators: name: Zhang, Weihe
name: Tyner, Jeffrey W.
name: Page, Lauren S.
name: Lee-Sherick, Alisa B.
name: Graham, Douglas K.
name: Huey, Madeline G.
name: Jacobsen, Kristen M.
name: Earp, H Shelton
name: Hill, Amanda A.
name: Kirkpatrick, Gregory G.
name: Frye, Stephen V.
name: Eryildiz, Fatma
name: Montgomery, Stephanie A.
name: Wang, Xiaodong
name: DeRyckere, Deborah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: MERTK tyrosine kinase is ectopically expressed in 30–50% of acute lymphoblastic leukemias (ALL) and over 80% of acute myeloid leukemias (AML) and is a potential therapeutic target. Here, we evaluated the utility of UNC2025, a MERTK tyrosine kinase inhibitor, for treatment of acute leukemia.
Relativistic Kinetic-Balance Condition for Explicitly Correlated Basis Functions
Creators: name: Simmen, Benjamin
name: Mátyus, Edit
name: Reiher, Markus
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This paper presents the derivation of a kinetic-balance condition for explicitly correlated basis functions employed in semi-classical relativistic calculations. Such a condition is important to ensure variational stability in algorithms based on the first-quantized Dirac theory of 1/2-fermions. We demonstrate that the kinetic-balance condition can be obtained from the row reduction process commonly applied to solve systems of linear equations. The resulting form of kinetic balance establishes a relation for the $4^N$ components of the spinor of an $N$-fermion system to the non-relativistic limit, which is in accordance with recent developments in the field of exact decoupling in relativistic orbital-based many-electron theory.
description: 27 pages, 1 table
The Low Redshift survey at Calar Alto (LoRCA)
Creators: name: Comparat, J.
name: Chuang, C. -H.
name: Rodriguez-Torres, S.
name: Pellejero-Ibanez, M.
name: Prada, F.
name: Yepes, G.
name: Courtois, H. M.
name: Zhao, G. -B.
name: Wang, Y.
name: Sanchez, J.
name: Maraston, C.
name: Metcalf, R. Benton
name: Peiro-Perez, J.
name: Kitaura, F. S.
name: Perez, E.
name: Delgado, R. M. Gonzalez
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The Baryon Acoustic Oscillation (BAO) feature in the power spectrum of galaxies provides a standard ruler to measure the accelerated expansion of the Universe. To extract all available information about dark energy, it is necessary to measure a standard ruler in the local, z<0.2, universe where dark energy dominates most the energy density of the Universe. Though the volume available in the local universe is limited, it is just big enough to measure accurately the long 100 Mpc/h wave-mode of the BAO. Using cosmological N-body simulations and approximate methods based on Lagrangian perturbation theory, we construct a suite of a thousand light-cones to evaluate the precision at which one can measure the BAO standard ruler in the local universe. We find that using the most massive galaxies on the full sky (34,000 sq. deg.), i.e. a K(2MASS)<14 magnitude-limited sample, one can measure the BAO scale up to a precision of 4\% and 1.2\% using reconstruction). We also find that such a survey would help to detect the dynamics of dark energy.Therefore, we propose a 3-year long observational project, named the Low Redshift survey at Calar Alto (LoRCA), to observe spectroscopically about 200,000 galaxies in the northern sky to contribute to the construction of aforementioned galaxy sample. The suite of light-cones is made available to the public.
description: 15 pages. Accepted in MNRAS. Please visit our website: http://lorca-survey.ft.uam.es/
title: Establishing of local DRLs for paediatric CT examinations in children hospital in Slovakia
Creators: name: Lehotska, Viera
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: In the last years also in Slovakia it was found a significant increase of the number of CT examinations, performed not only in the group of adult patients, but also for children. Because the number of CT procedures performed in a year, accounts for...
title: Time is Ripe! How to keep up with new technologies for radiation dose optimisation and find ways to incorporate these new developments in radiology equipment renewal
Creators: name: Akata, Deniz
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 4 - Quality of radiological equipment
subject: Action 3 - Image quality assessment based on clinical indications

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: Innovation in imaging technologies results in a better imaging quality while also improving security. Renewal of equipment in radiology necessitates awareness of recent advances in radiation dose management (Fig. 1). CT represents 19% of all X-ray...
Associations of characteristics of low-carbon mobility urban design features with cardio-metabolic health in Australia
Creators: name: Hadgraft, Nyssa
name: Bok, Barbara
name: Chandrabose, Manoj
name: Sugiyama, Takemi
name: Owen, Neville
name: Frantzeskaki, Niki
name: Newton, Peter
name: Woodcock, Ian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Environmental Public Health
subject: Public Health
subject: Medicine and Health Sciences

description: This is a registration for an updated systematic review protocol based on a previously registered rapid review https://osf.io/hk3zr This systematic review aims to assess the evidence for associations of characteristics of low-carbon mobility urban design features with cardio-metabolic health in Australia. Further details are provided in the attached protocol.
title: Modernisation of X-ray equipment is a real way of to improve radiation safety in X-ray diagnostics in conditions of limited financial resources
Creators: name: Kovalenko, Yuri
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 4 - Quality of radiological equipment
subject: Action 3 - Image quality assessment based on clinical indications

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: Today more than 20 million of routine chest examinations are performed in Ukraine annually [1]. More than 60 percent of them are make with the help of film fluorographs (Fig.1-2) the main disadvantages of which are low information content and high...
title: Influence of imaging technique on radiation exposure of the breast at mammography
Creators: name: Ivanac, Gordana
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 7 - Medical radiation protection research: MELODI, EURAMED
subject: Action 9 - Facilitation of research in advanced topics of radiation protection

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: Breast irradiation during mammography is dependant upon good positioning art, proper breast compression and appropriate exposure parameters, which are determined by AEC (automatic exposure control) in most routine instances, with restriction in...
Iterative Outlier Removal: A Method for Identifying Outliers in Laboratory Recalibration Studies
Creators: name: Couper, David
name: Grams, Morgan E.
name: Li, Danni
name: Selvin, Elizabeth
name: Wruck, Lisa M.
name: Sang, Yingying
name: Coresh, Josef
name: Parrinello, Christina M.
name: Eckfeldt, John H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Extreme values that arise for any reason, including through non-laboratory measurement procedure-related processes (inadequate mixing, evaporation, mislabeling), lead to outliers and inflate errors in recalibration studies. We present an approach termed iterative outlier removal (IOR) for identifying such outliers.
title: The Value of Structured Reporting in Improving Quality in Radiology
Creators: name: Mildenberger, Peter
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 8 - EuroSafe Imaging Stars network and data collection
subject: Action 1 - Clinical decision support, clinical imaging guidelines
subject: Action 1 - Guidelines, implementation policies, and Clinical Decision Support (ESR iGuide)
subject: Action 10 - EuroSafe Imaging Stars

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: Communication is one of the central issues in Radiology. For many years, there is a discussion on improvement of reporting in Radiology using templates with structured informations (so called "Structured Reporting"). Based on the definiton of a new...
Distilling Common History and Practice Elements to Inform Dissemination: Hanf-Model BPT Programs as an Example
Creators: name: Jacobs, Mary
name: Kaehler, Laura A.
name: Jones, Deborah J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: There is a shift in evidence-based practice toward an understanding of the treatment elements that characterize empirically-supported interventions in general and the core components of specific approaches in particular. The evidence-base for Behavioral Parent Training (BPT), the standard of care for early-onset disruptive behavior disorders (Oppositional Defiant Disorder and Conduct Disorder), which frequently co-occur with Attention Deficit Hyperactivity Disorder, is well-established; yet, an ahistorical, program-specific lens tells little regarding how leaders, including Constance Hanf at the University of Oregon, shaped the common practice elements of contemporary evidence-based BPT. Accordingly, this review summarizes the formative work of Hanf, as well as the core elements, evolution, and extensions of her work, represented in Community Parent Education (COPE; Cunningham, Bremner, & Boyle, 1995; Cunningham, Bremner, Secord, & Harrison, 2009), Defiant Children (DC; Barkley 1987; Barkley, 2013), Helping the Noncompliant Child (HNC; Forehand & McMahon, 1981; McMahon & Forehand, 2003), Parent-Child Interaction Therapy (PCIT; Eyberg, & Robinson, 1982; Eyberg, 1988; Eyberg & Funderburk, 2011), and the Incredible Years (IY; Webster-Stratton, 1981; 1982; 2008). Our goal is not to provide an exhaustive review of the evidence-base for the Hanf-Model programs; rather, our intention is to provide a template of sorts from which agencies and clinicians can make informed choices about how and why they are using one program versus another, as well as how to make inform flexible use one program or combination of practice elements across programs, to best meet the needs of child clients and their families. Clinical implications and directions for future work are discussed.
Small footprint nano-mechanical plasmonic phase modulators
Creators: name: Aksyuk, V. A.
name: Dennis, B. S.
name: Haftel, M. I.
name: Czaplewski, D. A.
name: Lopez, D.
name: Blumberg, G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: The authors' recent Nature Photonics article titled "Compact Nano-Mechanical Plasmonic Phase Modulators" [1] is reviewed which reports a new phase modulation principle with experimental demonstration of a 23 μm long non-resonant modulator having 1.5 π rad range with 1.7 dB excess loss at 780 nm. Analysis showed that by decreasing all dimensions, a low loss, ultra-compact π rad phase modulator is possible. Application of this type of nano-mechanical modulator in a miniature 2 x 2 switch is suggested and an optical design numerically validated. The footprint of the switch is 0.5 μm x 2.5 μm.
description: presented at Transducers 2015 Conference, Anchorage, AK
title: A Benchmark for X-Ray Practices: the Graph of Patient Doses
Creators: name: Olteanu, Bogdan Stefan
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 8 - EuroSafe Imaging Stars network and data collection
subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)
subject: Action 10 - EuroSafe Imaging Stars

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: Up to date there are no measurements of patient doses directly related to risk and irrespective of imaging method, exposed body part, patient's size, age and gender. Comparisons are possible only when all these factors are similar. For...
Beyond mean-field bistability in driven-dissipative lattices: bunching-antibunching transition and quantum simulation
Creators: name: Mendoza-Arenas, J. J.
name: Clark, S. R.
name: Felicetti, S.
name: Romero, G.
name: Solano, E.
name: Angelakis, D. G.
name: Jaksch, D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In the present work we investigate the existence of multiple nonequilibrium steady states in a coherently driven XY lattice of dissipative two-level systems. A commonly used mean-field ansatz, in which spatial correlations are neglected, predicts a bistable behavior with a sharp shift between low- and high-density states. In contrast one-dimensional matrix product methods reveal these effects to be artifacts of the mean-field approach, with both disappearing once correlations are taken fully into account. Instead, a bunching-antibunching transition emerges. This indicates that alternative approaches should be considered for higher spatial dimensions, where classical simulations are currently infeasible. Thus we propose a circuit QED quantum simulator implementable with current technology to enable an experimental investigation of the model considered.
Prevalence and risk factors for dementia in Latin America: A scoping review
Creators: name: Cárcamo, Paloma
name: Failoc-Rojas, Virgilio
name: Custodio, Nilton
name: Lanata, Serggio
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medical Sciences
subject: Public Health
subject: Medicine and Health Sciences
subject: Life Sciences
subject: Other Mental and Social Health
subject: Epidemiology
subject: Medical Specialties
subject: International Public Health
subject: Medical Neurobiology
subject: Neuroscience and Neurobiology
subject: Neurology
subject: Mental and Social Health
subject: alzheimer
subject: cognitive dysfunction
subject: cognitive impairment
subject: dementia
subject: latin america
subject: scoping review

description: A scoping review that aims to assess the body of literature regarding dementia and cognitive impairment in Latin America, as well as to identify existing gaps in knowledge, through exploration of the definitions for these conditions employed in studies and how they differ, the etiology of dementia in this geographic region and how often it is explored, and how studies approach socioeconomic determinants of dementia.
ارزیابی و درجه بندی سرمایه گذاری فعالیت های اقتصادی با رهیافت زمینه نفوذ و حذف فرضی
Publisher: name: دانشگاه کردستان
Year: 2022

description: کشف بخش های کلیدی اقتصاد، با توجه به ظرفیت ها و استعدادهای هر منطقه همواره مد نظر\nاقتصاددانان بوده است، چیزی که در ادبیات اقتصادی به مزیت نسبی تعبیر میشود. در پژوهش\nحاضر رتبه بندی سرمایه گذاری با استفاده از جدول داده - ستانده و سنجش اثرگذاری پیوندهای\nپسین و پیشین بخش های مختلف تعیین شده است. بدین منظور با استفاده از جدول داده - ستانده\nسال 1396( بهنگام شده از جدول 1390 مرکز آمار ایران( و روشهای نوین تعیین بخش کلیدی،\nاولویت سرمایه گذاری در کشور شناسایی شد. روش حذف فرضی نشان داد بخش های زراعت و\nباغداری، ساخت محصولات غذایی و ساخت مواد و فرآورده های شیمیایی دارای بالاترین\nپیوندهای پسین و پیشین هستند و اهمیت بالاتری دارند. در ادامه با استفاده از روش زمینه نفوذ مشخص شد که ساخت محصولات غذایی با مقدار 6416/252 دارای بیشترین زمینه نفوذ است و\nدر اولویت سرمایه گذاری است و سرمایه گذاری بیشتر در این بخش، رشد بیشتری را در تولید\nموجب میشود. پس از آن بخش ساخت مواد و فرآورده های شیمیایی با مقدار 4262/169 در\nاولویت دوم و سپس بخش زراعت و باغداری با مقدار 8038/150 در اولویت سوم سرمایه گذاری\nقرار دارد، بنابراین توصیه میشود به منظور استفاده از پتانسیل ها و ظرفیت های در بخش های\nاقتصادی در بخش محصولات غذایی و آموزش به عنوان بخش کلیدی سرمایه گذاری شود و\nسپس با توجه به مزیت نسبی بخش زراعت و باغداری سرمایه گذاری در این بخش نیز اجتناب\nناپذیر است
title: Optimisation and establishment of Diagnostic Reference Levels in paediatric plain radiography
Creators: name: Paulo, Graciano
Publisher: name: ESR EuroSafe Imaging
Year: 2016
Subjects: subject: Action 3 - Optimisation, diagnostic reference levels, image quality
subject: Action 2 - Clinical diagnostic reference levels (DRLs)

description: Background/Introduction Description of activity and work performed Conclusion and Recommendations Personal/Organisational information References
description: Background/Introduction: The risk of exposure to radiation is a permanent topic on the agenda of global organisations like the ICRP (www.icrp.org) 1 , the United Nations Scientific Committee on the Effects of Atomic Radiation 2 (UNSCEAR, www.unscear.org), the IAEA 3...
Natural history of bleeding and characteristics of early bleeders among warfarin initiators – a cohort study in Finland
Creators: name: Huupponen, Risto
name: Rikala, Maria
name: Kastarinen, Helena
name: Korhonen, Maarit Jaana
name: Tiittanen, Pekka
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: AimsThe demand for oral anticoagulant therapy will continue to increase in the future along with the aging of the population. This study aimed to determine the rate of bleeding requiring hospitalization and to characterize early bleeders among persons initiating warfarin therapy. Characterization of those most susceptible to early bleeding is important in order to increase the safety of warfarin initiation.Patients and methodsUsing data from nationwide health registers, we identified persons initiating warfarin therapy between January 1, 2009 and June 30, 2012, n=101,588, and followed them until hospitalization for bleeding, death, or administrative end of the study (December 31, 2012). We defined early bleeders as persons with a bleeding requiring hospitalization within 30 days since warfarin initiation.ResultsThe rate of hospitalization for bleeding during a median follow-up of 1.9 years was 2.6% per person-year (95% confidence interval [CI] 2.5%–2.7%), with a peak within the first 30 days of warfarin initiation (6.5% per person-year, 95% CI 6.0%–7.1%). In a multivariable Cox proportional hazards regression analysis, early bleeders were characterized by prior bleeding (<180 days before initiation, hazard ratio [HR] =13.7, 95% CI 10.9–17.1; during 180 days–7 years before initiation, HR =1.48, 95% CI 1.15–1.90), male sex (HR =1.32, 95% CI 1.10–1.57), older age (HR =1.13, 95% CI 1.04–1.22, per 10-year increase), venous thrombosis (HR =1.83, 95% CI 1.44–2.34), pulmonary embolism (HR =1.46, 95% CI 1.11–1.91), alcohol abuse (HR =1.59, 95% CI 1.08–2.35), rheumatic disease (HR =1.40, 95% CI 1.07–1.83), and exposure to drugs with dynamic interaction mechanism with warfarin (HR =1.43, 95% CI 1.20–1.71). In age-adjusted models, Charlson comorbidity index and number of drugs predicted a graded increase in the hazard of early bleeding.ConclusionThe rate of hospitalizations for bleeding peaked in the beginning of warfarin therapy. Early bleeders were characterized by venous thrombosis, pulmonary embolism, and factors that increase bleeding risk without affecting the international normalized ratio.