cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Evaluation of FUS-2000 urine analyzer: analytical properties and particle recognition
Creators: name: Beňovská, Miroslava
name: Ondřej Wiewiorka
name: Pinkavová, Jana
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Hematology
subject: 60506 Virology

description: This study evaluates the performance of microscopic part of a hybrid analyzer FUS-2000 (Dirui Industrial Co., Changchun, China), its analytical properties and particle recognition. The evaluation of trueness, repeatability, detection limit, carry-over, linearity range and analytical stability was performed according to Dirui protocol guidelines designed by Dirui Company to guarantee the quality of the instrument. Trueness for low, medium and high-value concentrations was calculated with bias of 15.5, 4.7 and −6.6%, respectively. Detection limit of 5 Ery/μl was confirmed. Coefficient of variation of 11.0, 5.2 and 3.8% was measured for within-run repeatability of low, medium and high concentration. Between-run repeatability for daily quality control had coefficient of variation of 3.0%. Carry-over did not exceed 0.05%. Linearity was confirmed for range of 0–16,000 particles/μl (R2 = 0.9997). The analytical stability had coefficient of variation of 4.3%. Out of 1258 analyzed urine samples, 362 positive were subjected to light microscopy urine sediment analysis and compared to the analyzer results. Cohen’s kappa coefficients were calculated to express the concordance. Squared kappa coefficient was 0.927 (red blood cells), 0.888 (white blood cells), 0.908 (squamous epithelia), 0.634 (transitional epithelia), 0.628 (hyaline casts), 0.843 (granular casts) and 0.623 (bacteria). Single kappa coefficients were 0.885 (yeasts) and 0.756 (crystals), respectively. Aforementioned results show good analytical performance of the analyzer and tight agreement with light microscopy of urine sediment.
Double phase transition in the triangular antiferromagnet Ba$_3$CoTa$_2$O$_9$
Creators: name: Ranjith, K. M.
name: Brinda, K.
name: Arjun, U.
name: Hegde, N. G.
name: Nath, R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Here, we report the synthesis and magnetic properties of a new triangular lattice antiferromagnet Ba$_3$CoTa$_2$O$_9$. The effective spin of Co$^{2+}$ is found to be $J=1/2$ at low temperatures due to the combined effect of crystal field and spin-orbit coupling. Ba$_3$CoTa$_2$O$_9$ undergoes two successive magnetic phase transitions at $T_{N1}\simeq0.70$~K and $T_{N2}\simeq0.57$~K in zero applied field, which is typical for triangular antiferromagnets with the easy-axis magnetic anisotropy. With increasing field, the transition anomalies are found to shift toward low temperatures, confirming the antiferromagnetic nature of the transitions. At higher fields, the transition peaks in the heat capacity data disappear and give way to a broad maximum, which can be ascribed to a Schottky anomaly due to the Zeeman splitting of spin levels. The $H-T$ phase diagram of the compound shows three distinct phases. The possible nature of these phases is discussed.
description: 6 pages, 7 figures
title: ADCO, Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Cart. 173 (11 H 939), 226 folios, f. 0286
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0286, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0286, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Sputum protein N-glycosylation in cystic fibrosis: a sweet response to bacterial colonisation
Creators: name: Venkatakrishnan, Vignesh
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Cystic fibrosis (CF) is a prevalent autosomal recessive disease characterised by chronicinfection and inflammation in the lungs. The damaged lungs secrete excess mucus that isexpectorated as sputum. The lung mucus is the primary site of microbial infection, withPseudomonas aeruginosa as one of the major infecting pathogens in CF patients. Alteration inglycosylation of mucins (heavily O-glycosylated proteins) has been shown to play a role inbacterial binding to the mucus in the lungs of CF patients. However, there has been littlereported on the N-glycosylation of the protein complement of CF sputum. We have characterized the total secreted protein N-glycome of sputum derived from five CFpatients, two non-CF patients infected with pathogens (iNCF) and two pathogen free non-CF(NCF) patients. The glycosylation difference between CF and iNCF, compared to betweeniNCF and NCF, sputum separates the role played by the CF disease itself in regulating Nglycanexpression as distinct from the effects of bacterial colonisation. A significant increasein unusual and truncated pauci-mannosidic N-glycans and a decrease in complex and hybridN-glycans on the sputum proteins were observed in CF and iNCF sputum compared to NCFsputum, suggesting a common effect of infection. To address the link between the variation in CF sputum N-glycans and bacterial colonisation,four P. aeruginosa clinical strains (PASS1, PASS2, PASS3 and PASS4) were isolated fromsputum of CF patients. We showed that secreted bacterial exoglycosidases were not thecause of the trimming of the N-glycans to pauci-mannosidic structures and that the bacterialproteins do not carry pauci-mannose N-glycans. The presence of the pauci-mannose Nglycanson the sputum proteins were thus not directly of bacterial origin. Proteomic analysis revealed an up-regulation of proteins involved in the immune response(specifically neutrophil proteins) in bacterial colonised (CF and iNCF) compared with noninfected(NCF) sputum. State-of-art site-specific N-glycoproteomic analysis of CF, iNCF andNCF sputum proteins showed that the abundant proteins of neutrophil origin, such asmyeloperoxidase and azurocidin, carried these truncated pauci-mannosidic N-glycans. Whilst abundant knowledge regarding mucin O-glycosylation is available in the literature,this study provides new structural N-glycan and site-specific N-glycoproteome informationto aid in understanding the complex cellular and molecular environment of the CF affectedrespiratory tract.
Cost-efficiency analysis and expanded treatment access modeling of conversion to rituximab biosimilars from reference rituximab in Jordan
Creators: name: Halawah, Hala H.
name: Alkhatib, Nimer S.
name: Almutairi, Abdulaali R.
name: Saleh, Mohammad
name: Halloush, Shiraz S.
name: Rashdan, Omar
name: Masadh, Lama
name: Abusara, Osama H.
name: Abraham, Ivo
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Science Policy
subject: Hematology

description: To assess the cost-efficiency and expanded access of three rituximab biosimilars versus the reference rituximab from the perspective of the Jordanian national health payer. A 1-year cost-efficiency and expanded access model of conversion from reference rituximab (Mabthera) to the approved biosimilars (Truxima, Rixathon, and Tromax) to assess five metrics: total annual cost to treat a hypothetical patient; head-to-head cost comparison; changes in patients’ access to rituximab; number-needed-to-convert (NNC) to provide an additional 10 patients access to a rituximab treatment; and relative amount of Jordanian Dinar (JOD) spent on rituximab options. The model included rituximab doses at 100 mg/10 ml and 500 mg/50 ml and considered both cost-saving and cost-wastage scenarios. Costs of treatments were based on the fiscal year 2022 tender prices received by the Joint Procurement Department (JPD). Rixathon was associated with the lowest average annual cost per patient (JOD2,860) across all six indications among all rituximab comparators, followed by Truxima (JOD4,240), Tromax (JOD4,365) and reference Mabthera (JOD11,431). The highest percentage of patient access to rituximab treatment (321%) was achieved when switching patients from Mabthera to Rixathon in the RA and PV indications. At four patients, Rixathon was associated with the lowest NNC to provide an additional 10 patients access to rituximab treatment. For each JOD1 spent on Rixathon, an additional JOD3.21 must be spent on Mabthera, an additional JOD0.55 on Tromax, and an additional JOD0.53 on Truxima. Rituximab biosimilars were associated with cost savings in all approved indications in Jordan compared to reference rituximab. Rixathon was associated with the lowest annual cost, the highest percentage of expanded patient access for all six indications, and the lowest NNC providing 10 additional patients with access.
Elucidating proton-mediated conformational changes in an acid-sensing ion channel 1a through molecular dynamics simulation
Creators: name: Liu, Lu
name: Yu, Hui
name: Yang, Lianjuan
name: Zhao, Xi
name: Huang, Xuri
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: Elucidating proton-mediated conformational changes in an acid-sensing ion channel 1a through molecular dynamics simulation
Lettre de Jean-Baptiste Marie de Piquet, marquis de Méjanes à Jean-François Séguier, 1770-10-03
Creators: name: marquis de Méjanes, Jean-Baptiste Marie de Piquet
name: Jean-Baptiste Marie De Piquet, Marquis De Méjanes
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Librairie

description: [transcription] J'ai reçu mon cher Monsieur les quatre-vingt-six livres pour prix des livres de Monsieur de Molins. J'ai fait tout au monde pour engager Monsieur Gandion à vous laisser le Banduri à 33 lt. mais il n'y a jamais eu moyen de réduire la cherté. Il a vendu déjà plus du tiers et à des demandes considérables d'Avignon. J'aurais voulu pouvoir remettre au commis de Monsieur Boudon les deux in folio, mais il n'a pas pu se charger étant à cheval. Je profiterai de la première occasion pour cous les faire parvenir et si de votre côté vous en savez quelqu'une vous aurez la bonté de me l'adresser. Je vérifierai le Banduri avant de l'envoyer et vous êtes toujours dans le droit de le faire reprendre s'il ne vous convient pas. Adieu mon cher Monsieur, je suis fort pressé et à peine me reste-t-il le temps de vous renouveler les assurances du tendre et sincère attachement avec lequel j'ai l'honneur d'être votre très humble et très obéissant serviteur.

Méjanes

Je vous prie de faire bien des compliments de ma part à Monsieur Boudon et de vouloir bien le remercier de l'attention obligeante qu'il a de me pourvoir des livres d'Italie.

Arles 3 octobre 1770.
description: [personnes citées] Antoine (Libraire) Gandion, Pierre Boudon de Clairac
description: [reférence bibliographique citée] Banduri, Anselmo, Numismata imperatorum Romanorum a Trajano Decio ad Palaeologos Augustos. Accessit Bibliotheca nummaria sive auctorum qui de re nummaria scripserunt. Opera et studio D. Anselmi
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 145_23, fol. 124
description: Source: ark:/12148/btv1b10015271s
Large scale text analysis of American Christian sermon content
Creators: name: Billet, Matthew
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Social and Behavioral Sciences

description: Religious sermons are cultural artefacts of immense importance. Particularly, in the United States, where sermons are generated and delivered locally, the content of these sermons are likely to be non-randomly spatially distributed across the nation in interesting ways that reflect social, political, geographical, and cultural differences in localities. By leveraging an incredible corpus of nearly 40,000 sermon transcripts from 2019-2020, we aim to describe what content is being delivered in American churches and how this content is regionally patterned. We are also interested to discover if local socio-ecological shock events have detectable consequences on sermon content.
Analysis of genetic diversity among some Iraqi durum wheat cultivars revealed by different molecular markers
Creators: name: Maeruf, Mihraban Sharif
name: Lateef, Djshwar Dhahir
name: Mustafa, Kamil Mahmood
name: Hamakareem, Hero Fatih
name: Abdalqadir, Shang Hasseb
name: Ahmad, Dastan Ahmad
name: Sleman, Shokhan Mahmood
name: Rasul, Kamaran Salh
Publisher: name: arXiv
Year: 2024
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Genomics (q-bio.GN)
subject: FOS: Biological sciences

description: Durum wheat has been cultivated since the beginning of crop domestication, occupying now the tenth ranking among the global most significant cultivated crops. Despite the fact that, the extent of the crop genetic diversity has not yet fully incorporated into modern varieties through breeding programs. In this study, a total of 35 markers (11 RAPD, 12 ISSR, and 12 CDDP) were utilized to assess the genetic variability and population structure of sixteen different cultivars of Iraqi durum wheat. Out of 294 bands obtained, 171 were identified as polymorphic: 47.00 polymorphic alleles from 98 RAPD bands, 53 polymorphic alleles from a total of 89 ISSR bands, and 71 alleles from 107 CDDP bands. The average number of observed alleles (Na), effective number of alleles (Ne), Shannon's information index (I), expected heterozygosity or gene diversity (He), unbiased expected heterozygosity (uHe), and polymorphic information content (PIC) (1.45, 1.38, 0.32, 0.22, 0.24, and 0.28, respectively) were obtained for RAPDs , (1.63, 1.45, 0.40, 0.27, 0.29, and 0.32, respectively) ISSRs and (1.35, 1.35, 0.31, 0.21, 0.23, and 0.30, respectively) for the CDDP markers. A dendrogram of two main clades (unweighted pair group method with arithmetic mean; UPGMA) and three populations of structure analysis, were obtained based on the three markers data. The analysis of molecular variance indicated 97.00%, 97.00%, and 90.00% variability within populations, applying RAPD, ISSR, and CDDP markers, respectively. The highest diversity indices were revealed in population 2 under the RAPD and CDDP markers, whereas population 1 had the highest values of these indices according to the ISSR markers. The results provide greater knowledge on the genetic makeup of Iraqi durum wheat cultivars, that facilitate future breeding programs of this crop.
description: 15
The shadow education market in Australia: a study of online tutoring intermediaries
Creators: name: Sturges, Megan
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This research examines the private tutoring market in NSW. While other researchers have conducted research on ‘learning centres’, this research focuses specifically on one-on-one ‘in home’ tutoring facilitated through online intermediaries. The methods encompass a content analysis of 65 websites that facilitate tutoring lessons, together with interviews with tutors who utilise these websites to find work. Within this thesis, the different intermediaries that exist within this market are classified and compared in relation to the functions that they perform. Research on online labour markets is used to try to explain how these intermediaries operate. This thesis also draws on classical economic sociology to explore the impact of different kinds of intermediation on tutors’ work and their relationships with their students. This shows the influence of intermediaries on the flexibility of the job of being a tutor and the way that tutors find students to tutor. I also demonstrate how tutors generate a trusting relationship between themselves and their students and show how intermediaries attempt to foster a similar relationship between their users.
title: ADCO, Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.2 (2e moitié XIIIe siècle), Cart. 167 (11 H 67), f. 0040v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Petot, Frédéric
name: Projet CBMA
name: CG21/F.PETOT/2010
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.2 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 167 (11 H 67), f. 0040v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.2 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 167 (11 H 67), f. 0040v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: abbaye de Cîteaux
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: http://www.wikidata.org/entity/Q843261
Female behaviour prior to additional sperm receipt in the hermaphroditic pond snail Lymnaea stagnalis
Creators: name: Moussaoui, Rabia
name: Verdel, Kevin
name: Benbellil-Tafoughalt, Saida
name: Koene, Joris M.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: In many species, sexual resistance by females can fluctuate depending on different physiological and/or ecological conditions. Based on theory, we decided to test whether the simultaneous hermaphrodite Lymnaea stagnalis becomes more reluctant to mate in the female role after receipt of an ejaculate. We aimed to test whether receipt of an ejaculate affects the expression of recipient behaviours, and whether this can have a potential effect on the outcome of mating interactions. We found that the expression of Crawl-out and Biting behaviours increased significantly in recently inseminated snails. Our data also indicated that an increase in expression of these latter behaviours can have direct effects on the outcome of the mating interactions. These findings suggest that under the influence of recent insemination, this hermaphroditic snail is more reluctant to accept another mating in the female role and may try to actively discourage the mounting snail (sperm donor). Hence, despite the fact that these simultaneous hermaphrodites express both sexual functions, there can still be variation in motivation to mate in either role.
Dissecting the liver tumour micro-environment: cell- and subcellular-specific characterisation of N-glycosylated basigin
Creators: name: Chatterjee, Sayantani
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Basigin (CD147), an N-glycosylated transmembrane protein occurring in four potential isoforms, isexpressed on surfaces of immune and cancer cells forming the heterogeneous tumour microenvironment.Basigin display pro- and anti-tumorigenic functions by interacting with multiplebinding partners; interactions that are modulated by glycosylation. However, the molecular featuresof basigin and the N-glycosylation of the cells of the tumour micro-environment remainundescribed. This thesis aimed to characterise the low abundance basigin from primary neutrophilsand HepG2 cancer cells as representative immune and cancer components of the liver tumourmicro-environment. Multiple enrichment and isolation strategies including immunoprecipitation,cell surface protein capture and plasma membrane separation were performed in conjunction withwestern blotting and advanced tandem mass spectrometry. For the first time, human basiginisoform-2 was successfully characterised from both neutrophils and HepG2 by extensive mappingof the polypeptide chain. Cell- and subcellular-specific N-glycomics revealed paucimannose-rich Nglycosylationof neutrophil plasma membranes and dominant high mannose type N-glycans ofHepG2 microsomes. In conclusion, glycobiology and powerful glyco-analytical technologies werebrought together to reveal novel molecular features of a key cancer and immune glycoprotein.These findings contribute to our understanding of the structure and function of basigin andsubcellular-specific N-glycosylation in the tumour micro-environment. (200 words)
Detecting Multi-Spin Interactions in the Inverse Ising Problem
Creators: name: Albert, Joseph
name: Swendsen, Robert H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: While the usual goal in Monte Carlo (MC) simulations of Ising models is the efficient generation of spin configurations with Boltzmann probabilities, the inverse problem is to determine the coupling constants from a given set of spin configurations. Most recent work has been limited to local magnetic fields and pair-wise interactions. We have extended solutions to multi-spin interactions, using correlation function matching (CFM). A more serious limitation of previous work has been the uncertainty of whether a chosen set of interactions is capable of faithfully representing real data. We show how our confirmation testing method uses an additional MC simulation to detect significant interactions that might be missing in the assumed representation of the data.
description: 5 pages, 3 figures
Additional file 1 of Role of diet in stroke incidence: an umbrella review of meta-analyses of prospective observational studies
Creators: name: Guo, Na
name: Zhu, Ying
name: Tian, Dandan
name: Zhao, Yating
name: Zhang, Chenguang
name: Mu, Changqing
name: Han, Chen
name: Zhu, Ruixia
name: Liu, Xu
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 1: Table S1. List of excluded full-text articles.
Additional file 1: of Fatigue and disturbances of sleep in patients with osteogenesis imperfecta – a cross-sectional questionnaire study
Creators: name: Arponen, Heidi
name: Waltimo-Sirén, Janna
name: Valta, Helena
name: Mäkitie, Outi
Publisher: name: figshare
Year: 2018
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer

description: Fatigue and disturbances of sleep in patients with Osteogenesis imperfecta –survey questionnaire. (DOCX 102 kb)
Healthcare resource utilization and cost among individuals with late-onset versus adult-onset Huntington’s disease: A claims‑based retrospective cohort study
Creators: name: To, Tu My
name: Ta, Jamie T
name: Patel, Anisha M
name: Arndorfer, Stella
name: Abbass, Ibrahim M
name: Gandhy, Rita
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: Mental Health

description: Aims: Quantify healthcare resource utilization (HRU) and costs for individuals with late-onset Huntington’s disease (LoHD) and compare these with adult-onset HD (AoHD) and non-HD controls. Methods: This retrospective cohort study used US healthcare claims data from the IBM MarketScan Commercial and Medicare Supplemental Databases. Individuals newly diagnosed with HD between 1/1/2009 and 12/31/2017 were selected (index date was first HD claim). Individuals ≥60 years of age at index date were categorized as having LoHD while individuals 21–59 years of age were categorized as having AoHD. Non‑HD controls were exact matched 2:1 to LoHD and AoHD cohorts. Individuals were required to have continuous enrollment for ≥12 months pre- and post-index. Twelve-month all-cause HRU and healthcare costs were assessed for each cohort. Results: In total, 763 individuals with LoHD and 1,073 individuals with AoHD were matched with 3,762 non-HD controls. Unadjusted all-cause HRU in the 12 months post-index was higher for individuals with LoHD and AoHD compared with non-HD controls across most service categories. Adjusted all-cause HRU for the LoHD cohort was significantly higher compared with non-HD controls across all service categories. In the 12 months post-index, mean total costs for the LoHD cohort ($29,055) were significantly higher than for non-HD controls (≥60 years old: $17,286; 21–59 years old: $12,688; p <.001) and similar to total costs in the AoHD cohort ($31,701; p =.47). Limitations: It was not possible to control for differences in HD stage but regression models were adjusted for baseline HRU. Evaluations of costs did not include indirect costs, which are known to be significant components of the wider HD burden. Conclusions: This study provides the first analysis of HRU and costs in LoHD, demonstrating that individuals with LoHD experience a significantly higher healthcare burden compared with non-HD controls and a similarly high burden compared with individuals with AoHD. Huntington’s disease (HD) usually develops between the ages of 30–50 but can develop earlier/later. This study looked at healthcare use in people who developed HD at age 60 or later in the United States. Researchers found that people who develop HD at age 60 or later have similar health needs to people with adult-onset HD. Furthermore, they have much greater health needs than people of a similar age who do not have HD.
Additional file 5 of Role of diet in stroke incidence: an umbrella review of meta-analyses of prospective observational studies
Creators: name: Guo, Na
name: Zhu, Ying
name: Tian, Dandan
name: Zhao, Yating
name: Zhang, Chenguang
name: Mu, Changqing
name: Han, Chen
name: Zhu, Ruixia
name: Liu, Xu
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 5: Table S5. Quality assessment of included meta-analyses using AMSTAR 2, without considering item 2 (sensitivity analysis).
Characterisation of surgeries beyond billing codes
Creators: name: Kennedy, Georgina
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The record of what occurred during a surgical procedure is typically represented in the electronic health record as a combination of unstructured text blocks (the operative report) with limited associated structured data. Billing codes fail to account for significant variance in procedures, thus although much of this information is valuable for real-time patient safety interventions, it is infrequently available for automated analysis. The selection of an appropriate ontological model provides a good foundation for effective information extraction and knowledge representation, allowing high quality inference and knowledge based concept identification. Through gap analysis and statistical analysis of the content of a corpus of operative notes, SNOMED CT has been selected as the most approriate knowledge model for automated information extraction in this domain. To successfully apply statistical natural language processing (NLP) methods developed on one corpus to another type of text, one must assume that there is a sufficient degree of similarity between the texts, both syntactically and semantically. From this, a determination is drawn as to the applicability of existing NLP clinical tools to the operative report. General clinical text was found to be not representative of the writing observed in operative reports. From this theoretical foundation, text classifiers were developed to demonstrate the feasibility of automatically encoding a subset of SNOMED CT terms in operative reports. Classification performance was high for detection of surgical specialty and open or closed procedures (f-score 0.965, 0.931 respectively); however, the detection of laterality was more reliable through heuristic methods.
Stellar ($n,γ$) cross section of $^{23}$Na
Creators: name: Uberseder, E.
name: Heil, M.
name: Käppeler, F.
name: Lederer, C.
name: Mengoni, A.
name: Bisterzo, S.
name: Pignatari, M.
name: Wiescher, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The cross section of the $^{23}$Na($n, γ$)$^{24}$Na reaction has been measured via the activation method at the Karlsruhe 3.7 MV Van de Graaff accelerator. NaCl samples were exposed to quasistellar neutron spectra at $kT=5.1$ and 25 keV produced via the $^{18}$O($p, n$)$^{18}$F and $^{7}$Li($p, n$)$^{7}$Be reactions, respectively. The derived capture cross sections $\langleσ\rangle_{\rm kT=5 keV}=9.1\pm0.3$ mb and $\langleσ\rangle_{\rm kT=25 keV}=2.03 \pm 0.05$ mb are significantly lower than reported in literature. These results were used to substantially revise the radiative width of the first $^{23}$Na resonance and to establish an improved set of Maxwellian average cross sections. The implications of the lower capture cross section for current models of $s$-process nucleosynthesis are discussed.
title: Lettre à Élisabeth Rouveix (Hôpital Ambroise Paré), Christian Perronne, Jean-Claude Melchior, Pierre de Truchis (Hôpital Raymond Poincaré)
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 pièce
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Cart. 185 (11 H 70), f. 0152r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0152r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0152r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Additional file 3: Table S2. of Epidemiology, genetic variants and clinical course of natural infections with Anaplasma phagocytophilum in a dairy cattle herd
Creators: name: Silaghi, Cornelia
name: Nieder, Marion
name: Sauter-Louis, Carola
name: Knubben-Schweizer, Gabriela
name: Pfister, Kurt
name: Pfeffer, Martin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Accession numbers of gene variants of A. phagocytophilum in comparison with variants from GenBank. (DOC 42Â kb)
A Swift X-ray view of the SMS4 sample -- II: X-ray properties of 17 bright radio sources
Creators: name: Maselli, Alessandro
name: Forman, William R.
name: Jones, Christine
name: Kraft, Ralph P.
name: Perri, Matteo
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Based on a proposal to observe 18 bright radio sources from the SMS4 catalog with the Neil Gehrels Swift Observatory (hereafter Swift), we obtained X-ray observations of 17 targets (one target was not observed). Following up our first paper that discussed 31 sources (see Maselli et al. 2022; 20 sources detected as point sources and one very extended source), we present results for this final sample of 17 radio sources, that previously lacked dedicated, pointed narrow FOV X-ray observations. One of these 17 sources, undetected by Swift due to a very short exposure, was instead detected by eROSITA, and given in the Data Release 1 (DR1) Catalog. No 1eRASS source was found in the DR1 for the remaining source, unobserved by Swift. The new Swift observations led to eleven X-ray source detections in the 0.3-10 keV band and six upper limits. We investigated the extent of the X-ray emission, the hardness ratio, and when statistics allowed we carried out a spectral analysis. The X-ray emission of eight sources is consistent with point-like emission, while three sources show clear evidence of extent, each with peculiar properties. We used the X-ray determined positions and uncertainties of the twelve detected sources to establish associations with infrared and optical sources from the AllWISE and the GSC 2.4.2 catalogs. Requiring a detection in both the infrared and the optical bands to establish a candidate counterpart for our X-ray detections, we identify counterparts for all twelve sources. We discuss the interesting structure of MRC B0344-345 and PKS B2148-555, two of the six extended X-ray sources that we detected in both our Swift campaigns, and suggest they are very promising for further X-ray and radio investigations. For the 38 SMS4 sources that lack pointed, narrow FOV X-ray telescope observations, after our Swift campaigns, we list 18 likely counterparts from the eROSITA DR1 catalog.
description: 25 pages, 7 figures, 11 tables; accepted for publication in the Astrophysical Journal Supplement Series. arXiv admin note: text overlap with arXiv:2208.04763
Ten-year cost-consequence analysis of weight loss on obesity-related outcomes in privately insured adults with obesity in Saudi Arabia
Creators: name: Al-Omar, Hussain A.
name: Aljehani, Nasser
name: Alshehri, Ali
name: Al-Khenizan, Abdullah
name: Al-Shammari, Faisal
name: Abanumay, Abdulmohsen
name: Schnecke, Volker
name: Carapinha, João L.
name: Alqhatani, Saleh A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Computational Biology

description: This study aimed to estimate the 10-year cost-consequence of weight loss on obesity-related outcomes in a sample of privately insured adults with obesity in Saudi Arabia (KSA). We analyzed data of adults with obesity (BMI ≥ 30 kg/m2) available in Nphies, the private health insurance platform of the Council of Health Insurance, KSA. A micro-costing analysis was used to obtain domestic cost estimates for obesity-related outcomes. Cox proportional hazard models were used to estimate the benefit of weight loss by preventing incident cases of 10 obesity-related outcomes. In the study cohort (n = 314,079), the 30–34.9 BMI category contributed two-thirds of the cohort, and no gender differences were found in the age distribution of BMI categories. The elderly population had a higher prevalence of obesity-related outcomes, such as hypertension, osteoarthritis, and type 2 diabetes mellitus (T2DM). The baseline cost (2023) for treating these outcomes was USD 1.245 billion, which could double in 10 years. A 15% weight loss could save USD 1.295 billion over 10 years, with most savings due to T2DM (USD 430 million), given its higher prevalence (27.5%). The model was most sensitive to cost variability in T2DM, dyslipidemia, and hypertension. The results should be interpreted within the bounds of the study cohort, and Nphies is in its early stages of implementation. The cost estimates may differ if repeated among adults with obesity only, potentially leading to increased cost savings with weight loss. Moderate weight loss of 5–15% over 10 years is associated with substantial cost savings in Saudi Arabia. For a 15% weight loss, 18.8% of incidence cases of obesity-related outcomes may be prevented, and slowed increases in T2DM, dyslipidemia, and hypertension may lead to considerable cost savings. The findings would help policymakers to implement weight loss programs in KSA.
Additional file 6 of Role of diet in stroke incidence: an umbrella review of meta-analyses of prospective observational studies
Creators: name: Guo, Na
name: Zhu, Ying
name: Tian, Dandan
name: Zhao, Yating
name: Zhang, Chenguang
name: Mu, Changqing
name: Han, Chen
name: Zhu, Ruixia
name: Liu, Xu
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 6: Fig. S1 Funnel plots for the association between A) total grains, B) whole grain, C) refined grain, D) whole grain bread, E) whole grain breakfast cereals, F) rice, G) oat and incidence of stroke. Fig. S2 Funnel plots for the association between A) fruits and vegetables, B) fruits, C) vegetables, D) potato and incidence of stroke. Fig. S3 Funnel plots for the association between A) fish, B) fatty fish, C) lean fish and incidence of stroke. Fig. S4 Funnel plots for the association between A) meat, B) red meat, C) processed meat, D) processed red meat, E) fresh red meat, F) white meat (poultry) and incidence of stroke. Fig. S5 Funnel plots for the association between eggs and incidence of stroke. Fig. S6 Funnel plots for the association between A) legumes, B) soy, C) nut, D) peanuts, E) tree nuts, F) walnuts, G) peanut butter, H) nut plus peanut butter and incidence of stroke. Fig. S7 Funnel plots for the association between A) dairy products, B) milk, C) cheese, D) cream, E) butter, F) yogurt and incidence of stroke. Fig. S8 Funnel plots for the association between chocolate and incidence of stroke. Fig. S9 Funnel plots for the association between A) coffee, B) tea, C) sugar-sweetened beverages, D) artificially sweetened beverage and incidence of stroke. Fig. S10 Funnel plots for the association between A) protein, B) animal protein, C) plant protein and incidence of stroke. Fig. S11 Funnel plots for the association between A) saturated fat, B) MUFA, C) n-3 PUFA, D) cholesterol, E) α-linolenic acid and incidence of stroke. Fig. S12 Funnel plots for the association between carbohydrate and incidence of stroke. Fig. S13 Funnel plots for the association between A) total fiber, B) soluble dietary fiber, C) insoluble dietary fiber, D) cereal fiber, E) fruit fiber, F) vegetable fiber and incidence of stroke. Fig. S14 Funnel plots for the association between A) vitamin B6, B) vitamin B12, C) vitamin C, D) vitamin D, E) vitamin E, F) vitamin K, G) folate acid, H) β-carotene, I) lycopene, J) dietary choline and incidence of stroke. Fig. S15 Funnel plots for the association between A) magnesium, B) calcium, C) potassium, D) sodium and incidence of stroke. Fig. S16 Funnel plots for the association between A) flavonoid, B) anthocyanins and incidence of stroke.
Health care resource utilization in 3L + patients with chronic phase chronic myeloid leukemia receiving asciminib or bosutinib
Creators: name: Cortes, Jorge E.
name: Rea, Delphine
name: Mauro, Michael J.
name: Tran, Diana
name: Wang, Pearl
name: Jadhav, Kejal
name: Yocolly, Aurore
name: Sasaki, Koji
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: To assess and compare health care resource utilization (HCRU) rates of asciminib and bosutinib at the Week 24, Week 48, and Week 96 cutoffs among 3 L + patients with chronic myeloid leukemia in chronic phase (CML-CP) in the randomized ASCEMBL trial. Patients in the ASCEMBL trial (Clinicaltrials.gov: NCT03106779) were randomized to receive asciminib 40 mg twice daily (n = 157) or bosutinib 500 mg once daily (n = 76). At each scheduled visit, investigators conducted HCRU assessment on hospitalization, emergency room visit, general practitioner visit, specialist visit and urgent care visit; duration and type of hospitalization for the hospitalized patients; and reasons for HCRU. The number of patients with HCRU, rate of HCRU per patient-year, and length of hospital stay by ward type were compared at Week 24, Week 48, and Week 96 analyses. Lower proportions of patients receiving asciminib versus bosutinib used any resources including hospitalizations, emergency room visits, general practitioner visits, specialist visits, and urgent care visits (23.6% versus 36.8%, 26.1% versus 39.5%, and 28.6% versus 42.6% at Week 24, Week 48, and Week 96 analyses, respectively). After normalizing for treatment exposure, rates of HCRU for any resource per patient-year were significantly lower for asciminib versus bosutinib: 0.25 (95% CI: 0.18–0.34) versus 0.80 (95% CI: 0.55–1.16) at the Week 24 analysis, 0.20 (95% CI: 0.15–0.27) versus 0.47 (95% CI: 0.32–0.66) at the Week 48 analysis, and 0.17 (95% CI: 0.12–0.22) versus 0.40 (95% CI: 0.27–0.55) at the Week 96 analysis. Among the hospitalized patients, mean length of hospital stay was lower for asciminib than bosutinib for most wards at all three timepoints. In the ASCEMBL trial, asciminib-treated patients with CML-CP in 3 L + maintained lower resource utilization compared to bosutinib over the long-term.
CXOGBS J174954.5-294335: A New Deeply-Eclipsing Intermediate Polar
Creators: name: Johnson, Christopher B.
name: Torres, M. A. P.
name: Hynes, R. I.
name: Jonker, P. G.
name: Heinke, C.
name: Maccarone, T.
name: Britt, C. T.
name: Steeghs, D.
name: Wevers, T.
name: Wu, Jianfeng
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present the results of a photometric and spectroscopic analysis of the Galactic Bulge Survey X-ray source CXOGBS J174954.5-294335 (hereafter, referred to as CX19). CX19 is a long period, eclipsing intermediate polar type cataclysmic variable with broad, single-peaked Balmer and Paschen emission lines along with HeII $\lambda4686$ and Bowen blend emission features. With coverage of one full and two partial eclipses and archival photometry, we determine the ephemeris for CX19 to be HJD(eclipse) = 2455691.8581(5) + 0.358704(2)$\times$N. We also recovered the white dwarf spin period of P$_{\rm spin}$ = 503.32(3) seconds which gives a P$_{\rm spin}$/P$_{\rm orb}$ = 0.016(6), comparable to several confirmed, long period intermediate polars. CX19 also shows a clear X-ray eclipse in the 0.3-8.0 keV range observed with Chandra. Two optical outbursts were observed lasting between 6-8 hours (lower limits) reaching $\sim$1.3 mags in amplitude. The outbursts, both in duration and magnitude, the accretion disc dominated spectra and hard X-ray emission are reminiscent of the intermediate polar V1223 Sgr sharing many of the same characteristics. If we assume a main sequence companion, we estimate the donor to be an early G-type star and find a minimum distance of $d \approx$ 2.1 kpc and a 0.5-10.0 keV X-ray luminosity upper limit of 2.0 $\times$ 10$^{33}$ erg s$^{-1}$. Such an X-ray luminosity is consistent with a white dwarf accretor in a magnetic cataclysmic variable system. To date, CX19 is only the second deeply-eclipsing intermediate polar with X-ray eclipses and the first which is optically accessible.
description: Accepted for publication in MNRAS, 25 pages, 15 figures, 1 table