cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Essays in gender economics
Creators: name: Lee, Jay Euijung
Publisher: name: London School of Economics and Political Science (LSE)
Year: 2020

description: This thesis investigates how gender norms limit women’s opportunities or hinder their performance, using a combination of macro and micro approaches. The first chapter quantifies the cost for aggregate economic output of conservative norms, which glue married women to the home. I develop a model of education, marriage, and labor force participation. I use the model and U.S. census data from 1940 to 2010 to estimate the homemaker norms wedge, which affects how married women discount their market wage when choosing between market work and home production. I then use the model to conduct counterfactual exercises, by taking current American families and assigning them different values of norms wedges. With norms wedges of 1940, aggregate output in 2010 falls by 3.5%; half of this decline is driven by lower education levels and the other half by an inefficient allocation of labor. The second chapter studies how highly male-dominated political parties react to the introduction of gender quotas in the context of South Korean municipal council elections. The results show that parties that are more intensely affected by the quota initially counter its effect by putting forth fewer female candidates where they can. However, those parties gradually increase the number of female candidates and three election cycles later, they field more female candidates – over and above the quota rules. The evidence suggests that this evolving response stems from parties becoming more favorably disposed towards women candidates, as they learn about the competence of women councilors. The third chapter estimates the afore-mentioned homemaker norms wedges for various countries around the world. It demonstrates that there is substantial cross-country variation and shows that differences in cultures regarding gender roles is an important explanatory factor.
Symbolic asynchronous hardware protocol verification for compositions with relative timing
Creators: name: Desai, Krishnaji
Publisher: name: University of Utah
Year: 2012
Subjects: BDD
Relative timing
SAT
Symbolic model checking
Timed asynchronous protocol
Verification

description: This thesis work provides a methodology and a tool fl  ow for verifying asynchronous hardware protocols through compositional model checking with symbolic methods. Correct interaction of asynchronous hardware protocols requires veri cation. Per-formance and power of asynchronous hardware circuits and protocols can be vastly improved by modifying them with judicious application of timing constraints. This approach uses relative timing constraints for modeling timed asynchronous hard-ware protocols. This work illustrates the modeling techniques for interleaving and simultaneous compositions with relative timing, which helps in pruning the reachable state space with an overhead of enforcing relative timing constraints. The modeling technique for relative timing does not alter the individual initial protocols. Relative timing constraints are enforced at the interface external to the protocol component.  Di erent modeling types are explored for modeling relative timing. Symbolic model checking is performed with properties required for ensuring compositional correctness using the NuSMV engine.
Sonnenfleckenzeichnung Nr. 22917.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.10.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
ONCOLOGISTS’ BARRIERS AND FACILITATORS FOR ONCOTYPE DX USE: QUALITATIVE STUDY
Creators: name: Bryson, Amy
name: Dinan, Michaela A.
name: Reeder-Hayes, Katherine
name: Dusetzina, Stacie B.
name: Weinberger, Morris
name: Roberts, Megan C.
name: Wheeler, Stephanie B.
Publisher: name: Cambridge University Press (CUP)
Year: 2016

description: BACKGROUND: Oncotype DX (ODX), a tumor gene profiling test, has been incorporated into clinical guidelines to aid in adjuvant chemotherapy decision making for early-stage, hormone receptor positive breast cancer patients. Despite United States (U.S.) guidelines, less than half of eligible women receive testing. Reasons for low usage are unclear: Our objective was to better understand U.S. oncologists' ODX uptake and how they use ODX during adjuvant chemotherapy decision making.
METHODS: We conducted semi-structured, ~30-minute phone interviews with medical and surgical oncologists in one U.S. State using purposive sampling. Oncologists were included if they saw greater than or equal to five breast cancer patients per week. Recruitment ended upon thematic saturation. Interviews were recorded, transcribed, and double-coded using template analysis.
RESULTS: During analysis, themes emerged across three domains. First, organizational factors (i.e., departmental structure, ODX marketing, and medical/insurance guidelines) influenced ease of ODX use. Second, oncologists referenced the influence of interpersonal factors (e.g., normative beliefs and peer use of ODX) over their own practices and recommendations. Third, intrapersonal factors (e.g., oncologist attitudes, perceived barriers, and research gaps) were discussed: although oncologists largely held positive attitudes about ODX, they reported challenges with interpreting intermediate scores for treatment decisions and explaining test results to patients. Finally, oncologists identified several research gaps.
CONCLUSIONS: As more tumor gene profiling tests are incorporated into cancer care for treatment decision making, it is important to understand their use in clinical practice. This study identified multi-level factors that influence ODX uptake into clinical practice, providing insights into facilitators and modifiable barriers that can be leveraged for improving ODX uptake to aid treatment decision making.
9,10-Dihydro-5-hydroxy-2,3,6-trimethoxyphenanthrene-1,4-dione: a new dihydrophenanthrene from commercial cannabis and its effect on zebrafish larval behaviour
Creators: name: Banskota, Arjun H.
name: Stefanova, Roumiana
name: Hui, Joseph P. M.
name: Berrué, Fabrice
name: Achenbach, John C.
name: Ellis, Lee
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: A new dihydrophenanthrene derivative namely 9,10-dihydro-5-hydroxy-2, 3,6-trimethoxyphenanthrene-1,4-dione (1) was isolated from commercial cannabis product together with 4,5-dihydroxy-2,3,6-trimethoxy-9,10-dihydrophenanthrene (2), 4-hydroxy-2,3,6,7-tetramethoxy-9,10-dihydrophenanthrene (3), combretastatin B-2 (4) and isocannbispiradienone (5). Structure elucidation of the isolated compounds were done based on the interpretation of the mass spectrometry (MS) and nuclear magnetic resonance (NMR) data. New dihydrophenanthrene derivative (1) was tested for its effect on zebrafish larval behaviour. Preliminary results suggested that the new dihydrophenanthrene derivative (1) exhibits similar effect on zebrafish larval behaviour as cannabidiol (CBD), a biologically active component of Cannabis.
IFAD Research Series 84: Farmed animal production in tropical circular food systems
Creators: name: Oosting, Simon
name: Van Der Lee, Jan
name: Verdegem, Marc
name: De Vries, Marion
name: Vernooij, Adriaan
name: Bonilla-Cedrez, Camila
name: Kabir, Kazi
name: Oosting, Simon
name: Van Der Lee, Jan
name: Verdegem, Marc
name: De Vries, Marion
name: Vernooij, Adriaan
name: Bonilla-Cedrez, Camila
name: Kabir, Kazi
Publisher: name: Unknown
Year: 2022
Subjects: subject: Agricultural and Food Policy
subject: Farm Management
subject: Livestock production
subject: aquaculture
subject: climate change mitigation
subject: pollution
subject: farming systems

description: For farmed animal production in the tropics, there are two important food system outcomes: supplying animal-sourced food to ensure healthy diets for all; and contributing to climate change mitigation and minimizing pollution. In this review, the role of farmed animals in circular food systems in the tropics is presented in four case studies. The impacts of circularity on food security and environmental impact mitigation are discussed. Farmed animals are important in circular food systems because they use land unsuited to crop production, they upgrade crop residues, and they supply manure for crop production. However, their increased demand puts pressure on important aspects of circularity, such as minimizing food-feed competition, maximizing use of waste streams in feed, and the value of manure for fertilization.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.12.1968, erstellt von Vasile Dinulescu, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Neural stem cells in early development
Creators: name: Cai, Jingli
Publisher: name: University of Utah
Year: 2012
Subjects: Stem cells
Central nervous system - Growth
Developmental neurobiology

description: Neural stem cells (NSCs) undergo self-renewal and give rise to all differentiated cell types including astrocytes, oligodendrocytes and neurons in the nervous system. Their capacity of active proliferation and differentiation into multiple phenotypes makes them ideal candidates for clinical application such as replacement in many neurodegenerative disorders and other diseases of the nervous system. Various populations of NSCs can be isolated from different positions along the rostrocaudal axis in both embryonic and adult central nervous system (CNS). For my thesis work, I have taken advantage of a pure population of neuroepithelial cells (NEP), a type of embryonic NSCs isolated from rat E10.5 neural tube to address several aspects of stem cell biology. First, NEP cells were examined to identify markers which are unique to NSCs. Multiple markers were tested including many utilized for isolating hematopoietic stem cells (HSCs). I then analyzed membrane properties of NEP cells by examining ion channel gene expression using a focused microarray and current recording with whole cell patch clamping. To extend the understanding of NEP cells and to search for possible new NSC markers. My colleagues and I used several focused microarrays to compare the NEP cells expression pattern with a mixed population of El4.5 spinal cord cells containing both neuronal restricted precursor (NRP) and glial restricted precursor (GRP) cells. Finally, to determine   how   NEP   cells   differentiate   into   glial   lineage,   I   used   a   PCR-based subtractive suppression hybridization (SSH) to identify differently expressed genes and several glial specific genes were identified and characterized. My results broaden the understanding of fetal NSCs by enlarging the marker pool for characterizing and providing new methods for isolating fetal NSCs from mixture populations. Similar experiments performed in adults will deepen the understanding of NSCs of the molecular mechanism regulating cell fate decisions.
Profile of phenolic compounds in jabuticaba (Myrciaria sp.) a potential functional ingredient
Creators: name: Santos, Mônica Cristine Pereira dos
name: Cavalcanti, Elisa d’Avila Costa
name: Santos, Millena C. Barros
name: Seljan, Mariana Pulmar
name: Cameron, Luiz Claudio
name: Ferreira, Mariana Simões Larraz
name: de Andrade Gonçalves, Édira Castello Branco
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: Phenolic compounds have attracted a lot of attention due to their benefits to human health. Jabuticaba (Myrciaria sp.) fruit has been described as an excellent source of these compounds, while Jabuticaba leaf, considered as plant residue, has shown functional effects. The present study aimed to characterize the phenolic profile in two different leaves extracts (hydroalcoholic ethanol and butanol) of Myrciaria sp. by UPLC-ESI-QTOF-MSE. A total of 40 phenolic compounds were tentatively identified. Jabuticaba leaf extracts presented a rich and diversified composition of phenolic compounds, especially flavonoids, being ellagic acid, quercetin 3-O-glucoside, gallocatechin, and epigallocatechin the most abundant in butanol extracts. Very distinct phenolic profiles were obtained depending on the the solvent indicating that specific preparations can be obtained from the jabuticaba leaf depending on the desired application. This work emphasized the potential of this residue vegetable to be used as a functional ingredient.
Methodologic Framework to Identify Possible Adverse Drug reactions Using Population-Based Administrative Data
Creators: name: Sauer, Brian C.
Publisher: name: University of Utah
Year: 2012
Subjects: Drugs - Side effects
Drugs - Side effects - Data processing
Medical informatics

description: We present a framework for detecting possible adverse drug reactions (ADRs)  using Utah Medicaid administrative data. We examined four classes of ADRs  associated with treatment of dementia by acetylcholinesterase inhibitors (AChEIs):  known reactions (gastrointestinal, psychological disturbances), potential reactions  (respiratory disturbance), novel reactions (hepatic, hematological disturbances), and  death.  Our cohort design linked drug utilization data to medical claims from Utah  Medicaid recipients. We restricted the analysis to beneficiaries 50 years and older  who had a dementia-related diagnosis. We compared patients treated with AChEIs to  patients untreated with antidementia medication therapy. We attempted to remove  confounding by establishing propensity-score-matched cohorts for each outcome  investigated; we then evaluated effects of drug treatment by conditional multivariable  Cox-proportional-hazard regression. Acute and transient effects were evaluated by a  crossover design using conditional logistic regression.  Propensity-matched analysis of expected reactions found that AChEI treatment  was associated with gastrointestinal episodes (hazards ratio [HR]: 2.02; 95%  confidence interval [CI]: 1.28-3.2) but not psychological episodes, respiratory  disturbance, or death. Among the tested unexpected reactions, the risk was higher  with hematological episodes (HR: 2.32; 95% CI: 1.47-3.6) but not hepatic episodes. We also noted a trend towards an increase in the odds of experiencing acute  hematological events in the treated group (odds ratio [OR]: 3.0; 95% CI: 0.97-9.3).  We observed an expected association between AChEIs and gastrointestinal  disturbances and detected a signal of hematological adverse drug events (ADEs) after  treatment with AChEIs in this pilot study. Using our analytic framework may raise  awareness of potential ADEs and generate hypotheses for future investigations.
Sonnenfleckenzeichnung Nr. 22892.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.09.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
The Association Between Men’s Concern About Demonstrating Masculine Characteristics and Their Sexual Risk Behaviors: Findings from the Dominican Republic
Creators: name: Brito, Maximo O.
name: Lerebours, Leonel
name: Barrington, Clare
name: Fleming, Paul J.
name: Gottert, Ann
name: Powell, Wizdom
name: Donastorg, Yeycy
Publisher: name: Springer Nature
Year: 2016

description: Quantitative analyses exploring the relationship between masculinities and men’s sexual risk behaviors have most commonly used one dimension of masculinities: men’s gender ideology. Examining other dimensions may enhance our understanding of and ability to intervene upon this relationship. In this article, we examined the association between gender role conflict/stress (GRC/S)—men’s concern about demonstrating masculine characteristics—and three different sexual risk behaviors (having two or more sex partners in the last 30 days; never/inconsistent condom use with non-steady partners; and drinking alcohol at last sex) among a sample of heterosexual men in the Dominican Republic who were participating in an HIV prevention intervention (n = 293). The GRC/S Scale we used was adapted for this specific cultural context and has 17 items (α = 0.75). We used logistic regression to assess the relationship between GRC/S and each sexual behavior, controlling for sociodemographic characteristics. In adjusted models, a higher GRC/S score was significantly associated with increased odds of having two or more sex partners in the past 30 days (AOR 1.33, 95 % CI 1.01–1.74), never/inconsistent condom use with non-steady partners (AOR 1.45, 95 % CI 1.04–2.01), and drinking alcohol at last sex (AOR 1.56, 95 % CI 1.13–2.17). These results highlight the importance of expanding beyond gender ideology to understanding the influence of GRC/S on men’s sexual risk behaviors. Interventions should address men’s concern about demonstrating masculine characteristics to reduce the social and internalized pressure men feel to engage in sexual risk behaviors.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.12.1968, erstellt von Georgeta Maris, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Optical sequence time domain reflectrometry for aircraftwire fault detection
Creators: name: Dhamija, Hemang
Publisher: name: University of Utah
Year: 2012
Subjects: Airplanes--Electric wiring
Electric fault location

description: Aircraft today are being used well beyond their expected lifetime. Although regular maintenance and troubleshooting is thoroughly done, wiring on the aircraft is an issue that still needs to be resolved. Over the last decade, increasingly high importance has been given to aircraft wiring as wiring has been the root cause of some major aircraft disasters. This thesis discusses some of the methods used to detect faults on aircraft wires  and the need to develop faster and more efficient methods to do the same. The work done in this thesis focuses on acousto optics SSTDR (AO-SSTDR) methods to develop wire fault detection systems on aircrafts and discusses the results obtained from the research.  The AO-SSTDR architecture leverages the correlation properties of acousto-optic crystals. This research aims at achieving a better resolution and faster processing times than some of its electrical counterparts. Once commercialized, this research can be a promising solution to the aging aircraft wiring problems and the aviation industry, thus saving hundreds of lives and millions of dollars to the aviation industry.
Design, synthesis and herbicidal activities of p-menth-3-en-1-amine thiourea derivatives
Creators: name: Zhu, Shou-ji
name: Li, Jin-feng
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: An efficient method for the synthesis of 1-isopropyl-4-isothiocyanato-4-methylcyclohex-1-ene has been developed with p-menth-3-en-1-amine as raw material. Next, a number of p-menth-3-en-1-amine thiourea derivatives (4a–f) have been obtained from the reactions between 1-isopropyl-4-isothiocyanato-4-methylcyclohex-1-ene and cyclohexylamine or the reactions between p-menth-3-en-1-amine and different isothiocyanates. Then, the herbicidal activities of these compounds were evaluated. The result indicated that some of these newly synthesised compounds displayed remarkable herbicidal activities against annual ryegrass. In addition, the derivative containing cyclohexane ring (4a) displayed much higher herbicidal activity against annual ryegrass than the derivatives containing benzene ring.
Astaena Erichson 1847
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Melolonthidae
Astaena

description: Astaena sp.
Distribution. Suriname: MHCN; RMNH - NEW COUNTRY RECORD (Suriname, [Para], Zanderij. 2/ 6-X-1964. D. C. Geijskes.).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 118, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 22869.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.08.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 22904.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.09.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Erratum to: Phase I and pharmacokinetic evaluation of the anti-telomerase agent KML-001 with cisplatin in advanced solid tumors
Creators: name: Liu, Tao
name: Styblo, Miroslav
name: Edelman, Martin J.
name: Feliciano, Josephine
name: Lapidus, Rena
name: Gobburu, Jogarao
name: Beumer, Jan H.
Publisher: name: Springer Nature
Year: 2016

description: N/A
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.12.1968, erstellt von Gisèle Evrard-Kesteloot, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
A new lignan from the stems of Buchanania lucida Blume (Anacardiaceae)
Creators: name: Nguyen, Nhan Trung
name: Dang, Phu Hoang
name: Nguyen, Hai Xuan
name: Le, Tho Huu
name: Van, Truong Nhat
name: Nguyen, Mai Thanh Thi
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology

description: From the EtOAc-soluble extract of the stems of Buchanania lucida, one new lignan, (+)-(8S,8′S)-5′-methoxy-4,4′-di-O-methylsecoisolariciresinol (1), together with five known compounds (2–6) were isolated. Their structures were elucidated on the basis of NMR spectroscopic interpretation. The absolute configuration of 1 was determined based on the Cotton effects in the ECD spectrum. In the tyrosinase inhibitory activity test, p-hydroxybenzoic acid (6) showed the strong effect, with an IC50 value of 9.35 µM.
Many-body and spin-orbit aspects of the alternating current phenomena
Creators: name: Glenn, Rachel
Publisher: name: University of Utah
Year: 2014
Subjects: Quantum-dot
Rabi
Rashba
Spin-orbit
Spin-pair
Zeeman

description: The thesis reports on research in the general  field of light interaction with matter. According to the topics addressed, it can be naturally divided into two parts: Part I, many-body aspects of the Rabi oscillations which a two-level systems undergoes under a strong resonant drive; and Part II, absorption of the ac field between the spectrum branches of two-dimensional fermions that are split by the combined action of Zeeman and spin-orbit (SO) fields. The focus of Part I is the following many-body effects that modify the conventional Rabi oscillations: Chapter 1, coupling of a two-level system to a single vibrational mode of the environment. Chapter 2, correlated Rabi oscillations in two electron-hole systems coupled by tunneling with strong electron-hole attraction. In Chapter 1, a new effect of Rabi-vibronic resonance is uncovered. If the frequency of the Rabi oscillations, R, is close to the frequency, !0, of the vibrational mode, the oscillations acquire a collective character. It is demonstrated that the actual frequency of the collective oscillations exhibits a bistable behavior as a function of  ΩR ω0. The main finding in Chapter 2 is, that the Fourier spectrum of the Rabi oscillations in two coupled electron-hole systems undergoes a strong transformation with increasing ΩR. For ΩR smaller than the tunneling frequency, the spectrum is dominated by a low-frequency (<
Presentación Abriendo espacios para la Ciencia Abierta
Creators: name: Peñailillo Acuña, Mauricio
name: Sáez-Alarcón, Daniela
Publisher: name: Zenodo
Year: 2024
Subjects: Ciencia Abierta
Repositorio Institucional
Infraestructura y Servicios

description: El proyecto InES Ciencia Abierta INCA210005 financiado por la Agencia Nacional de Investigación y Desarrollo (ANID) de Chile fue adjudicado por la Universidad Católica de la Santísima Concepción (UCSC) en el año 2021. En marco de la divulgación de los conocimientos y resultados adquiridos durante su ejecusión, se participó activamente en encuentros y seminarios atenientes a las temáticas de Ciencia Abierta, entre los cuales, destaca el mejoramiento realizado de la infraestructura y los servicios insitucionales.

El documento contempla la presentación del desarrollo del Repositorio Institucional UCSC en su análisis y procesos durante la ejecusión del proyecto.

La presentación fue realizada durante la Semana de Acceso Abierto, organizada por la Universidad de Chile, Pontificia Universidad Católica de Chile y Universidad de Concepción (https://semanaaccesoabierto.cl/).
description: Financiado por la Agencia Nacional de Investigación y Desarrollo (ANID) de Chile. Proyecto INCA210005.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.09.1968, erstellt vermutlich von Dendis am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Phosphorus removal from manganese ore by plasma treatment
Creators: name: Hwang, Su Hyun
Publisher: name: University of Utah
Year: 2012
Subjects: Ferro-manganese
Manganese ore
Phosphorus
Plasma

description: The contents of impurities, especially that of phosphorus, in manganese metal or in ferromanganese used in steelmaking are an important factor that affects product quality. More than 80% of phosphorus in the manganese products is introduced from manganese ore, the rest coming from coke and lime. Once it is absorbed into a molten manganese ore ferromanganese phase, it cannot be easily removed by smelting, and thus, ferromanganese must generally be low in phosphorus to begin with. As good quality ores of low phosphorus are depleted, the phosphorus content in manganese ores increases, and thus, the development of a new dephosphorization technology is needed.  For this purpose, the removal of phosphorus compounds by vaporization directly from manganese ores using a plasma system was investigated in this study. For the removal of phosphorus, the effects of argon gas flow rate, hydrogen gas content in the plasma gas, and plasma torch power were analyzed. In addition, based on the thermal decomposition of hematite in the ores into magnetite at a high temperature, a magnetic separation was conducted after plasma treatment aiming to upgrade manganese ores. For the removal of phosphorus, a low argon gas flow rate and a high torch power were found to be effective, and the use of hydrogen gas as a reducing agent was more favorable than without. Magnetic separation after plasma treatment improved the ore grade with a decrease of iron content in the ore.
Modeling psychiatric disorders: from genomic findings to cellular phenotypes
Creators: name: Sun, Y-M
name: Glover, J C
name: Harwood, A J
name: Posthuma, D
name: Djurovic, S
name: Sullivan, P F
name: Peitz, M
name: Brüstle, O
name: Shen, S
name: Falk, A
name: Heine, V M
Publisher: name: Springer Nature
Year: 2016

description: Major programs in psychiatric genetics have identified >150 risk loci for psychiatric disorders. These loci converge on a small number of functional pathways, which span conventional diagnostic criteria, suggesting a partly common biology underlying schizophrenia, autism and other psychiatric disorders. Nevertheless, the cellular phenotypes that capture the fundamental features of psychiatric disorders have not yet been determined. Recent advances in genetics and stem cell biology offer new prospects for cell-based modeling of psychiatric disorders. The advent of cell reprogramming and induced pluripotent stem cells (iPSC) provides an opportunity to translate genetic findings into patient-specific in vitro models. iPSC technology is less than a decade old but holds great promise for bridging the gaps between patients, genetics and biology. Despite many obvious advantages, iPSC studies still present multiple challenges. In this expert review, we critically review the challenges for modeling of psychiatric disorders, potential solutions and how iPSC technology can be used to develop an analytical framework for the evaluation and therapeutic manipulation of fundamental disease processes.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.11.1968, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622
Prevalence of Malaria Parasitaemia among Children Resident in Orphanages in Anambra State, Nigeria
Creators: name: Ifeoma Enweani
Publisher: name: figshare
Year: 2020
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences

description: Malaria parasitemia in Anambra State and in Nigeria at large is of public health significance. Determination of malaria parasite density is helpful in disease monitoring and assessment of drug efficacy. This study investigated the prevalence of malaria parasitemia among children resident in orphanages located in Anambra State, Nigeria and related the malaria parasite density gotten from actual WBC count with value got using World Health Organization (WHO) assumed mean. A total of 272 subjects comprising 172 orphans and 100 children in family setting (controls) were investigated for malaria parasitemia using Giemsa stain. Malaria parasite density was carried out according to WHO recommendation. A prevalence of 23.3% and 12.0% malaria parasitemia were observed for children in orphanage and family setting respectively (p<0.05). The disease significantly affected the children in all the age ranges with children in ages 0-5 most affected (p<0.05). The mean malaria parasite density measured based on WHO assumed WBC mean value was significantly higher than using the actual WBC count (p˂0.05). The use of total WBC count reference value for a given locality in measuring malaria parasite density is recommended rather than an assumed value.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.08.1968, erstellt am Sonnenobservatorium der Universität Teheran
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Zeichnung von Sonnenflecken (Bleistift und Farbstift), erstellt als Projektionsbildzeichnung in Teheran.
Unter Umständen im Zusammenhang mit Beobachtungen des Air Weather Service der U.S. Air Force im Auftrag des NASA Controll Centers in Houston erstellt. Instrument: unbekannt.
Instrument unbekannt
Behaviors of peers and supervisors as perceived by impaired nurse colleagues: a descriptive study
Creators: name: Hardy, Connie H.
Publisher: name: University of Utah
Year: 2012
Subjects: Interpersonal Relations
Rehabilitation
Social Perception
Adaptation, Psychological
Professional Impairment

description: The purposes of this study were (a) to describe the perceived behaviors of supervisors and peers toward a group of recovering impaired nursing during their period of addiction, (b) to describe behaviors impaired nurses felt might have been helpful in facilitation recovery, and (c) to compare the perceived behavior to the profession's stated responsibilities to protect the public from incompetent nursing care and to assist the impaired nurse colleague toward restoration of health.  Through the use of indepth interviews which were part of a larger study, 21 impaired nurses provided descriptions of the perceived behaviors of colleagues toward them.  From the perspective of their own personal experience, impaired nurses identified the behaviors that were nonhelpful, that is, that allowed the addictive process to continue.  Group dynamics of staff members sometimes evolved into enabling responses which were perceived to be an impediment to the recovery process.  The nurses also described behaviors that were perceived as supportive and facilitative of treatment and offered suggestions related to behavior that might have been helpful in assisting them to prevent, recognize, and seek treatment for their addictive illness.  The preponderance of perceived nonhelpful responses indicated a potential problem in the implementation of an ethical code into day-by-day behaviors of nurses confronting this particular ethical dilemma.  As nurses described their unique experiences with the complex phenomenon of addiction and subsequent experiences with theirs peers and supervisor, information was generated to assist the profession and individual nurses to provide intervention reflective of the profession's commitment to quality patient care and humanistic concern for impaired colleagues.
Aplodema rufescens Saylor 1938
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Aplodema
Aplodema rufescens

description: Aplodema rufescens Saylor, 1938
Haplodema rufescens Saylor 1938: 73 (Guyana)
Distribution. Guyana: Saylor 1938: 73 (as Haplodema rufescens); Blackwelder 1944: 221; Evans and Smith 2009: 310.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 118, DOI: 10.5281/zenodo.3678492
Copaifera langsdorffii Desf. bark extract: optimisation of dyeing conditions to wool and colour fastness properties
Creators: name: dos Santos Silva, Patricia Muniz
name: França, Vitória Hamawaki
name: de Queiroz, Rayana Santiago
name: de Lima, Fernando Soares
name: Freeman, Harold S.
name: da Costa, Silgia Aparecida
name: da Costa, Sirlene Maria
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: The ability to add value to waste materials from industrial operations has come to the attention of the wood processing industry, with reports, for example, of extracts from the bark tree conveying colour and UV protection to textile fibres. The objective of the present work was to expand our developments in this arena by using Copaifera langsdorffii Desf. bark extract as a natural dye for textile dyeing. A complete 2³-statistical experimental design and the central point was elaborated. The results showed that the optimal dyeing conditions were 98 °C, for 60 min, using undiluted bark extract. The dyed fabric was analysed by a spectrophotometer using the CIELAB system for evaluation of the colour strength. The results showed a K/S value of 5.78, and the dyed fabric had good colour fastness to rubbing and washing.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.08.1968, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622
A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections
Creators: name: Kharabora, Oksana
name: Ngasala, Billy
name: Mårtensson, Andreas
name: Balasubramanian, Sujata
name: Saunders, David L.
name: Hathaway, Nicholas J.
name: Björkman, Anders
name: Jamnik, Andrew
name: Juliano, Jonathan J.
name: Meshnick, Steven R.
name: Lon, Chanthap
name: Mideo, Nicole
name: Read, Andrew F.
name: Bailey, Jeffrey A.
Publisher: name: Oxford University Press (OUP)
Year: 2016

description: BACKGROUND AND OBJECTIVES: Current tools struggle to detect drug-resistant malaria parasites when infections contain multiple parasite clones, which is the norm in high transmission settings in Africa. Our aim was to develop and apply an approach for detecting resistance that overcomes the challenges of polyclonal infections without requiring a genetic marker for resistance.
METHODOLOGY: Clinical samples from patients treated with artemisinin combination therapy were collected from Tanzania and Cambodia. By deeply sequencing a hypervariable locus, we quantified the relative abundance of parasite subpopulations (defined by haplotypes of that locus) within infections and revealed evolutionary dynamics during treatment. Slow clearance is a phenotypic, clinical marker of artemisinin resistance; we analyzed variation in clearance rates within infections by fitting parasite clearance curves to subpopulation data.
RESULTS: In Tanzania, we found substantial variation in clearance rates within individual patients. Some parasite subpopulations cleared as slowly as resistant parasites observed in Cambodia. We evaluated possible explanations for these data, including resistance to drugs. Assuming slow clearance was a stable phenotype of subpopulations, simulations predicted that modest increases in their frequency could substantially increase time to cure.
CONCLUSIONS AND IMPLICATIONS: By characterizing parasite subpopulations within patients, our method can detect rare, slow clearing parasites in vivo whose phenotypic effects would otherwise be masked. Since our approach can be applied to polyclonal infections even when the genetics underlying resistance are unknown, it could aid in monitoring the emergence of artemisinin resistance. Our application to Tanzanian samples uncovers rare subpopulations with worrying phenotypes for closer examination.
Characterizing diatom assemblages in ponded wetlands
Creators: name: Hultquist, Arne D.
Publisher: name: University of Utah
Year: 2012
Subjects: Diatoms
Environment
Ordination
Sampling
Surface-sediment
Wetlands
Diatom assemblages

description: Using biological assemblages for evaluating ecosystem integrity is dependent upon robust sampling techniques that adequately characterize the species composition.  This thesis evaluated the performance of a wetland surface-sediment diatom collection methodology. The methodology did not result in collection of 95% of species present due to the richness of rare species in the ponded wetlands. However, because rare species added little to relative abundance, the method provided a community characterization that separated the communities based upon ponds within complexes  and ponds between complexes. The mantel test indicated species distribution was dependent upon pond and complex (p
Inactivation of tumor suppressors LKB1 and PTEN by arachidonic acid metabolites
Creators: name: Covey, Tracy Marie
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Metabolism
subject: Physiology
subject: FOS: Biological sciences
subject: Pathology

description: This dissertation describes the modification and inactivation of tumor suppressors by arachidonic acid (AA) metabolites. Cyclooxygenase (COX) and lipoxygenase (LOX) enzymes are AA metabolizing enzymes involved in inflammation as well as cancer. In this work, a novel mechanism linking inflammation and cancer is presented.  LKB1 is a serine/threonine kinase that activates AMP-Kinase, thereby regulating anabolic and catabolic processes in the cell. LKB1 has a nucleophilic cysteine in its activation loop. Chapter 2 demonstrates the covalent modification of LKB1 by clectrophilic, cyclopcntcnone prostaglandins. Formation of this covalent adduct in the activation loop inhibits the kinase activity of LKB1 and prevents the phosphorylation and activation of its substrate AMPK. This affects downstream signaling to important enzymes such as Aeetyl-CoA Carboxylase and S6-Kinase, preventing an appropriate response to low energy levels.  PTEN is a phosphoinositol phosphatase and tumor suppressor involved in regulating the PI3K-Akt pathway. Chapter 3 illustrates the oxidation of PTEN by reactive oxygen lipid species generated during AA metabolism by COX-2 and 5-LOX. Oxidation of PTEN decreases its phosphatase activity, favoring increased PIP3 production, activation of Akt, and phosphorylation of downstream Akt targets including GSK-3[3 and S6K. These effects are reeapitulated with pancreatic PLA2, which hydrolyzes the release of membrane-bound AA.  Chapter 4 describes the covalent modification and inactivation of PTEN by cyclopentenone prostaglandins. Chapter 3 and 4 illustrate that covalent modification and oxidation of tumor suppressors during AA metabolism are not exclusive, but may both occur and contribute tumor suppressor inactivation.  In summary, this work investigates two novel mechanisms involving the chemical inactivation of tumor suppressors at the protein level. Interference with the physiological roles of tumor suppressors may confer risk for hypertrophic or neoplastic diseases associated with chronic inflammation or unwarranted oxidative metabolism of essential fatty acids. These events likely occur as the results of constant exposure to eicosanoid metabolites and byproducts during chronic inflammation or during COX/LOX overexpression, giving rise to decreased sensitivity to anti-growth signals and the promotion of tumorigenesis.