cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The pathogenic effect of SNPs on structure and function of human TLR4 using a computational approach
Creators: name: Prakasam, Priya
name: Salam, Abdul Ajees Abdul
name: Ahamed, Syed Ibrahim Basheer
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: The human toll-like receptor (hTLR) 4 single nucleotide polymorphisms (SNPs) are interconnected with cancer, multiple genetic disorders and other immune-related diseases. The detrimental effect of SNPs in hTLR4 with respect to structure and function has not been explored in depth. The present study concatenates the biological consequences of the SNPs along with structural modifications predicted at the hTLR4 gene. A total of 7910 SNPs of hTLR4 were screened, and 21 damage-causing SNPs were identified. Out of 21, seven are present in the extracellular region, of which three were detected as deleterious and the fourth one as moderate. These three mutations are located in a highly conserved region and influence conformational change. The change leads to the widening of the Leucine-rich repeat (LRR) arc to a maximum of 16.9 Å and a minimum of 8.7 Å. Expansion/shortening of LRR arc, never discussed before, would cause loss of myeloid differentiation factor 2 (MD-2) interactions in the interior and diminish lipopolysaccharide (LPS) responses. Similarly, in all mutant structures, the binding region for HMGB1 and LPS is deflating or in an unsupportive conformation. Thus, SNPs affect the regular signaling cascade and might result in human sepsis, genetic disorders, cancer and other immunological related diseases. Communicated by Ramaswamy H. Sarma
title: Cervical malignant extrarenal rhabdoid tumor
Creators: name: Gomez-Pena, Sara
Publisher: name: EURORAD
Year: 2021
Subjects: subject: Paediatric radiology
subject: Oncology
subject: Paediatric
subject: MR
subject: Clinical Cases

description: Clinical History: A 6-month-old infant with personal background of preterm twin birth and DiGeorge syndrome diagnosis was referred to our centre for progressive hydrocephalus with intracranial hypertension.

After ventriculoperitoneal shunt surgery, the patient underwent a cerebral and spinal MRI.

description: 6 months, female
Barium stars as tracers of s-process nucleosynthesis in AGB stars II. Using machine learning techniques on 169 stars
Creators: name: Hartogh, J. W. den
name: López, A. Yagüe
name: Cseh, B.
name: Pignatari, M.
name: Világos, B.
name: Roriz, M. P.
name: Pereira, C. B.
name: Drake, N. A.
name: Junqueira, S.
name: Lugaro, M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We aim to analyse the abundance pattern of 169 Barium (Ba) stars, using machine learning techniques and the AGB final surface abundances predicted by Fruity and Monash stellar models. We developed machine learning algorithms that use the abundance pattern of Ba stars as input to classify the initial mass and metallicity of its companion star using stellar model predictions. We use two algorithms: the first exploits neural networks to recognise patterns and the second is a nearest-neighbour algorithm, which focuses on finding the AGB model that predicts final surface abundances closest to the observed Ba star values. In the second algorithm we include the error bars and observational uncertainties to find the best fit model. The classification process is based on the abundances of Fe, Rb, Sr, Zr, Ru, Nd, Ce, Sm, and Eu. We selected these elements by systematically removing s-process elements from our AGB model abundance distributions, and identifying those whose removal has the biggest positive effect on the classification. We excluded Nb, Y, Mo, and La. Our final classification combines the output of both algorithms to identify for each Ba star companion an initial mass and metallicity range. With our analysis tools we identify the main properties for 166 of the 169 Ba stars in the stellar sample. The classifications based on both stellar sets of AGB final abundances show similar distributions, with an average initial mass of M = 2.23 MSun and 2.34 MSun and an average [Fe/H] = -0.21 and -0.11, respectively. We investigated why the removal of Nb, Y, Mo, and La improves our classification and identified 43 stars for which the exclusion had the biggest effect. We show that these stars have statistically significant different abundances for these elements compared to the other Ba stars in our sample. We discuss the possible reasons for these differences in the abundance patterns.
description: accepted for publication in A&A
Red Giant Eclipsing Binaries: Exploring Non-Oscillators And Testing Asteroseismic Scalings
Creators: name: Rawls, Meredith L.
name: Gaulme, Patrick
name: McKeever, Jean
name: Jackiewicz, Jason
Publisher: name: Zenodo
Year: 2016
Subjects: asteroseismology
red giants
eclipsing binaries

description: Thanks to advances in asteroseismology, red giants have become astrophysical laboratories for probing the Milky Way. Eclipsing binaries allow us to directly measure stellar properties independently of asteroseismology, which we use to investigate why some red giants don't oscillate and test asteroseismic scaling relations for those that do. By combining orbital solutions, high-resolution spectroscopy, and stellar evolution models for a subset of eight eclipsing red giants observed by Kepler, we find short-period binaries with strong tidal forces and systems with active red giants are less likely to exhibit solar-like oscillations. We also preview the results from Gaulme et al. 2016 (submitted). We find asteroseismic scalings overestimate red giant radii by about 6% on average and masses by about 16% in ten systems observed by Kepler. Systematic overestimation of mass leads to underestimation of stellar age, which has important implications for ensemble asteroseismology applied to galactic studies.
description: Poster #305. Postdoc Poster Award winner and subsequently invited to speak. Slides from that talk are included.
description: {"references": ["Gaulme et al. 2016, submitted to ApJ", "Gaulme et al. 2014, ApJ, 785, 5", "Gaulme et al. 2013, ApJ, 767, 82", "Rawls et al. in prep", "Rawls et al. 2016, ApJ, 818, 108"]}
Numerical modeling techniques for assessing three-dimensional diffusion processes in heterogeneous rock samples on the sub-mm scale
Creators: name: Ellis, Scotland Russell
Publisher: name: University of British Columbia
Year: 2010

description: The burial of high level nuclear wastes in geologic repositories requires careful consideration of the long-term hydrogeological and geochemical stability of the receiving formations. Care must be taken due to the high environmental sensitivity of the waste material and its potential long-term effect on groundwater. Studies into the host rocks' natural ability to minimize contaminant migration are a matter of high priority in the planning for long-term storage of high level radioactive waste. Focusing on porous sedimentary rock, this study aims to examine numerical techniques used to analyze and interpret experimental data that characterize the distribution of porosity in geologic samples at the µm to mm scale. Because repositories are hosted in natural fine-grained rock formations, transport in the vicinity of these repositories is diffusion-controlled and believed to be affected substantially by heterogeneities at these scales. Data available for the analyses consist of non-destructive, high-resolution measurements of porosity obtained using new developments in X-ray imaging. Advances in computing technology make it possible to numerically analyze the expected patterns of sub-mm-scale diffusive transport for these large experimental data sets. The modeling analyses examine 3D diffusive transport in heterogeneous rock samples and evaluate the effect of data resolution and image processing techniques on the connectivity of the transport pathways. The simulation results provide insight into small-scale diffusive transport of solutes, and guide the needs for dataset resolution and handling for these types of investigations. With increased availability of experimental results, further modeling studies could be conducted. These studies would aim at developing a link between simulation results and observed data to further develop the transport theory for contaminant migration on this scale.
On a Boundary-Value Problem for One Class of Differential Equations of the Fourth Order with Operator Coefficients
Creators: name: Aliev, A. R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 34G10, 34K10, 35J40, 47D03

description: The boundary-value problem on semi-axis for one class operator-differential equations of the fourth order, the main part of which has the multiple characteristic is investigated in this paper in Sobolev type weighted space. Correctness and unique solvability of the boundary-value problem is proved, and the solvability conditions are expressed in terms of the operator coefficients of the equation. Estimations of the norms of the operators of intermediate derivatives, closely connected with the solvability conditions, have been carried out. The connection between the exponent of the weight and the lower border of the spectrum of the main operator, participating in the equation, is determined in the results of the paper.
Lower the Stakes: A Public Health Approach to Gambling in British Columbia: Provincial Health Officer’s 2009 Annual Report
Creators: name: British Columbia. Provincial Health Officer.
Publisher: name: Ministry of Health [British Columbia]
Year: 2013
Subjects: subject: Gambling -- British Columbia
subject: Compulsive gamblers -- British Columbia
subject: Gambling Literature

description: Permission to include in Alberta Gambling Research Institute research repository granted by Intellectual Property Program on October 24, 2013. File Number: 7200003122
description: This Provincial Health Officer’s annual report examines gambling in BC using a comprehensive public health approach. A public health approach considers preventive interventions, health promotion, health protection, and assessment and surveillance, and addresses issues related to quality of life for all members of the community. In applying such an approach, this report acknowledges and incorporates the health, social, and economic dimensions of gambling. It reviews the history of gambling in Canada and BC, describes current gambling policies and programs in BC, and examines evidence-based strategies to minimize the negative effects of gambling while optimizing the potential benefits.
title: The COVID-19 Pandemic in Asia and Africa. Societal Implications, Narratives on Media, Political Issues. Volume I – culture, art, media
Creators: name: Milanetti, Giorgio
name: Miranda, Marina
name: Morbiducci, Marina
Publisher: name: Sapienza Università Editrice
Year: 2023

description: The present publication has been conceived as a critical reflection, in different disciplinary fields, on the social, institutional, and cultural impact of the recent COVID-19 pandemic in Asia and Africa. The issues presented here were first discussed as part of a larger research project at two conferences, held in Rome in June and October 2022. After extensive revision, these results have now been collected as fully developed articles in the current two volumes: the first focuses on the cultural, artistic, and media-related facets of the pandemic; the second on its social and institutional implications.

This Volume I examines the effects of the traumatic events brought about by the COVID-19 pandemic on various cultural phenomena, artistic expressions, and social media communication, analysing among other themes the creation of new narratives and the modalities of personal and collective responses. The articles cover vast geographical areas, spanning from the Middle East to the Indian Subcontinent and East Asia, and aim at making their multiple visions converge in one compact perspective of empathic connection.
The rotation of Mimas
Creators: name: Noyelles, Benoît
name: Karatekin, Özgür
name: Rambaux, Nicolas
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The Cassini mission in the Saturnian system is an outstanding opportunity to improve our knowledge of the satellites of Saturn. The data obtained thanks to this mission must be confronted to theoretical models. This paper aims at modeling the rotation of Mimas, with respect to its possible internal structure. For that, we first build different interior models, in considering Mimas as composed of 2 rigid layers with different porosity. Then we simulate the rotational behavior of these models in a 3-degree of freedom numerical code, in considering complete ephemerides of a Mimas whose rotation is disturbed by Saturn. We also estimate the deviation of its longitudinal orientation due to tides. We expect a signature of the internal structure up to 0.53° in the longitudinal librations and an obliquity between 2 and 3 arcmin, the exact values depending on the interior. The longitudinal librations should be detectable, inverting them to get clues on the internal structure of Mimas is challenging.
Constant Chemical Potential-Quantum Mechanical-Molecular Dynamics simulations of the Graphene-electrolyte double layer
Creators: name: Di Pasquale, Nicodemo
name: Finney, Aaron R.
name: Elliott, Joshua
name: Carbone, Paola
name: Salvalaglio, Matteo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present the coupling of two frameworks -- the pseudo-open boundary simulation method known as constant potential Molecular Dynamics simulations (C$μ$MD), combined with QMMD calculations -- to describe the properties of graphene electrodes in contact with electrolytes. The resulting C$μ$QMMD model was then applied to three ionic solutions (LiCl, NaCl and KCl in water) at bulk solution concentrations ranging from 0.5 M up to 6 M in contact with a charged graphene electrode. The new approach we are describing here provides a simulation protocol to control the concentration of the electrolyte solutions while including the effects of a fully polarizable electrode surface. Thanks to this coupling, we are able to accurately model both the electrode and solution side of the double layer and provide a thorough analysis of the properties of electrolytes at charged interfaces, such as the screening ability of the electrolyte and the electrostatic potential profile. We also report the calculation of the integral electrochemical double layer capacitance in the whole range of concentrations analysed for each ionic species, while the QM simulations provide access to the differential and integral quantum capacitance. We highlight how subtle features, such as the adsorption of potassium at the interface or the tendency of the ions to form clusters, emerge from our simulations, contribute to explaining the ability of graphene to store charge and suggest implications for desalination.
description: 28 pages, 10 figures
Flux-Flux And Activity-Rotation Relationships In Early-M Dwarfs
Creators: name: Maldonado, J.
name: Scandariato, G.
Publisher: name: Zenodo
Year: 2016
Subjects: stars: activity
stars: late-type
stars: low-mass
stars: chromospheres
stars: fundamental parameters
techniques: spectroscopic

description: While most of the planets discovered so far have been found orbiting around solar-type stars, low-mass stars have been recognised as a "shortcut" to glance into an exo-life

laboratory. Currently, stellar activity is one of the most limiting factors for achieving the precision required to detect Earth-twins via the radial velocity method. Understanding the

chromospheres of M dwarfs is crucial to solve this problem. In this contribution we present a study of the activity-rotation-stellar parameters and flux-flux relationships among a

large sample of early-M dwarfs which are currently being monitored in the framework of the HADES (HArps-n red Dwarf Exoplanet Survey) radial velocity survey (see also the

posters by Affer et al., and Scandariato et al.).
A survey of pathological gamblers in the state of Ohio
Creators: name: Culleton, R. P.
name: Transition Planning Associates
Publisher: name: Transition Planning Associates
Year: 1985
Subjects: subject: Compulsive gambling -- Ohio
subject: Gamblers -- Ohio
subject: Gambling Literature

description: Permission to include in Alberta Gambling Research Institute research repository granted by Dr. Robert P. Culleton on October 30, 2013.
Quantum Algorithms for Quantum Field Theories
Creators: name: Jordan, Stephen P.
name: Lee, Keith S. M.
name: Preskill, John
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Quantum field theory reconciles quantum mechanics and special relativity, and plays a central role in many areas of physics. We develop a quantum algorithm to compute relativistic scattering probabilities in a massive quantum field theory with quartic self-interactions (phi-fourth theory) in spacetime of four and fewer dimensions. Its run time is polynomial in the number of particles, their energy, and the desired precision, and applies at both weak and strong coupling. In the strong-coupling and high-precision regimes, our quantum algorithm achieves exponential speedup over the fastest known classical algorithm.
description: v2: appendix added (15 pages + 25-page appendix)
Die Auswirkungen Der 6. Iv-Revision Auf Betroffene: Rente Weg - Was Nun?
Creators: name: Cacciato, Antonio
name: Erismann, Theresia
Publisher: name: Zenodo
Year: 2016
Subjects: subject: gnd:4291280-5
subject: gnd:4128792-7
subject: gnd:4137265-7
subject: gnd:4055776-5
subject: gnd:4055676-1
subject: gnd:4053881-3

description: Das Sozialversicherungssystem der Schweiz ist vielfältig und komplex. Ein bedeutender Teil davon ist die Invalidenversicherung (IV). Diese soll Menschen unterstützen, die ihren Lebensunterhalt aufgrund einer Beeinträchtigung nicht durch eigene Arbeitsleistung bestreiten können. Der stete Rentenanstieg in den 1990er Jahren führte die Versicherung in die roten Zahlen. Der Bund sah Handlungsbedarf und steuerte eine Rentenrevision nach der anderen an, teils bevor die vorhergehende Revision sich auswirken konnte. Die 6. IV-Revision hat die Zahl der Renten massiv minimiert und damit vielen Menschen die finanzielle Lebensgrundlage genommen. Die vorliegende qualitative Forschungsarbeit soll aufzeigen, wo diese Menschen heute stehen, und wie ihre aktuelle Situation aussieht. Im ersten Teil wird die Invalidenversicherung beleuchtet, danach wird anhand der Identitätsbildungstheorie aufgezeigt, mit welchen Problemen die Betroffenen zu kämpfen haben, wenn das Selbstbild und das Fremdbild nicht mehr übereinstimmen. Diese Anpassung hat ein erstes Mal zu erfolgen, wenn die betroffene Person aufgrund der Invalidität aus dem Erwerbsprozess ausscheidet und wiederholt sich in verstärktem Mass, wenn die Rente gestrichen wird. Wie ein kritisches Lebensereignis bewältigt wird, ist stark abhängig von den persönlichen Ressourcen, die ein Mensch zur Verfügung hat. Viele Betroffene suchen Hilfe. Sozialarbeitende begegnen diesen Menschen auf den Beratungsstellen oder dem Sozialamt, wenn ein Antrag auf materielle Unterstützung gestellt wird. Deshalb ist es für Sozialarbeitende wichtig, die Auswirkungen der 6. IV-Revision auf Betroffene zu kennen und damit besser zu verstehen, wozu die vorliegende Arbeit einen Beitrag leisten kann.
description: + Code Diss LU: hslusa basa 2016 + Fussnote: Ausbildungsgang Sozialarbeit
The role of phase compatibility in martensite
Creators: name: Salman, Oguz Umut
name: Finel, Alphonse
name: Delville, Remi
name: Schryvers, Dominique
Publisher: name: arXiv
Year: 2012
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Shape memory alloys inherit their macroscopic properties from their mesoscale microstructure originated from the martensitic phase transformation. In a cubic to orthorhombic transition, a single variant of marten- site can have a compatible (exact) interface with the austenite for some special lattice parameters in contrast to conventional austenite/twinned martensite interface with a transition layer. Experimentally, the phase compat- ibility results in a dramatic drop in thermal hysteresis and gives rise to very stable functional properties over cycling. Here, we investigate the microstructures observed in Ti50Ni50-xPdx alloys that undergo a cubic to orthorhombic martensitic transformation using a three dimensional phase field approach. We will show that the simulation results are in very good agreement with transmission electron microscopy observations. However, the understanding of the drop in thermal hysteresis requires the coupling of phase transformation with plastic activity. We will discuss this point within the framework of thermoelasticity, which is a generic feature of the martensitic transformation.
description: Accepted for publication in in Journal of Applied Physics
Diode effect in Josephson junctions with a single magnetic atom
Creators: name: Trahms, Martina
name: Melischek, Larissa
name: Steiner, Jacob F.
name: Mahendru, Bharti
name: Tamir, Idan
name: Bogdanoff, Nils
name: Peters, Olof
name: Reecht, Gael
name: Winkelmann, Clemens B.
name: von Oppen, Felix
name: Franke, Katharina J.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Current flow in electronic devices can be asymmetric with bias direction, a phenomenon underlying the utility of diodes and known as non-reciprocal charge transport. The promise of dissipationless electronics has recently stimulated the quest for superconducting diodes, and non-reciprocal superconducting devices have been realized in various non-centrosymmetric systems. Probing the ultimate limits of miniaturization, we have created atomic-scale Pb--Pb Josephson junctions in a scanning tunneling microscope. Pristine junctions stabilized by a single Pb atom exhibit hysteretic behavior, confirming the high quality of the junctions, but no asymmetry between the bias directions. Non-reciprocal supercurrents emerge when inserting a single magnetic atom into the junction, with the preferred direction depending on the atomic species. Aided by theoretical modelling, we trace the non-reciprocity to quasiparticle currents flowing via Yu-Shiba-Rusinov (YSR) states inside the superconducting energy gap. Our results open new avenues for creating atomic-scale Josephson diodes and tuning their properties through single-atom manipulation.
Interactions between β-cyclodextrin as a carrier for anti-cancer drug delivery: a molecular dynamics simulation study
Creators: name: Boroushaki, Tahereh
name: Dekamin, Mohammad G.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: A series of molecular dynamics simulations were performed on 5-fluorouracil (5-Fu), Alendronate (Ald), and Temozolomide (TMZ) anticancer drugs in the presence and absence of β-cyclodextrin (βCD) as a carrier. Thermodynamic investigations showed that the van der Waals interaction energy was dominant in loading all drugs inside the βCD cavity. The sum of the interaction energies illustrated that the highest affinity was related to Ald (−136.5 kJ/mol), which in turn was due to the presence of bulky and charged atoms of phosphorus and oxygen, although TMZ (−115.92 kJ/mol) showed a very high affinity as well. At the same time, the hydrogen bond analysis also represented that Ald had the most hydrogen bond (1.97) with the highest half-life (3.13 ps) with βCD. Investigation of the root mean fluctuation (RMSF) indicated that all the drugs had a relatively rigid structure and maintain this rigidity during loading in the βCD cavity, and in the meantime, Ald was slightly more flexible than 5-Fu and TMZ. The area of ​the primary hydroxyl rim decreased in all drug-containing systems, which in turn was caused by the attractive interaction of drugs with oxygens in the primary hydroxyl rim. Especially for those drugs that were able to penetrate to the end of the primary hydroxyl rim of the βCD, that means TMZ and 5-Fu. Meanwhile, due to the lack of Ald penetration to the end of the primary hydroxyl rim, the area change in the Ald-containing system was less than in the two others. Communicated by Ramaswamy H. Sarma
Gambling Prevalence in South Australia : October to December 2005
Creators: name: Population Research And Outcome Studies Unit
Publisher: name: South Australian Department for Families and Communities
Year: 2006
Subjects: subject: Gambling -- South Australia
subject: Gambling -- South Australia -- Statistics
subject: Gambling Literature

description: Permission to include in Alberta Gambling Research Institute research repository granted by Glenn Palmer (DCSI) on March 3, 2014.
description: Over 17,000 South Australian adults were interviewed for the gambling survey. Telephone interviewing was used, with numbers being randomly selected from the White Pages. This gambling survey follows the methodology of the 2001 study, which was, at that time, the largest survey undertaken to examine gambling patterns in South Australia. The current survey is three times larger than the 2001 survey. This survey examined a wide range of gambling patterns. These included: • how frequently people gamble; • types of gambling most commonly used; and • awareness of support services to assist gamblers with a problem.
Ich Weiss Was Ich Will! Wohnwünsche Und -Träume Aus Dem Blickwinkel Von Menschen Mit Einer Kognitiven Behinderung, Die In Einer Institution Leben: Eine Qualitative Forschungsarbeit, Welche Betroffene Als Expertinnen Und Experten Befragt
Creators: name: Gisler, Daniela
name: Streit, Annina
Publisher: name: Zenodo
Year: 2016
Subjects: subject: gnd:4019841-8
subject: gnd:4053881-3
subject: gnd:4066749-2
subject: gnd:4055676-1
subject: gnd:4135889-2
subject: gnd:4294827-7

description: Seit der Ratifizierung des Übereinkommens über die Rechte von Menschen mit Behinderungen (BRK) durch die Schweiz vor etwas mehr als eineinhalb Jahren sollen auch Menschen mit kognitiver Behinderung ihren Aufenthaltsort selbstbestimmt wählen dürfen und eine unabhängigere Lebensführung geniessen können. Zudem stellen die laufenden Veränderungen in der Behindertenhilfe Institutionen vor grosse Herausforderungen, dies, indem sie sich umorientieren müssen: Weg vom Angebot, hin zur Ausrichtung am Bedarf von Menschen mit einer kognitiven Behinderung. Um möglichst adäquate Wohnangebote zu schaffen, ist das Wissen um Wohnwünsche und -träume von Betroffenen wesentlich. Die Arbeit zeigt auf, welche Leitprinzipien in der Behindertenhilfe prägend sind, welche Wohnformen bestehen und welche Herausforderungen sich daraus ergeben. Weiter sind Wohnwünsche und -träume von Menschen mit einer kognitiven Behinderung, die in einer Institution leben, erfasst. Es wird ersichtlich, dass Betroffene Wohnwünsche und -träume haben, die von der erlebten Situation in der Institution abweichen. Für die vorliegende qualitative Forschungsarbeit werden insgesamt acht Interviews durchgeführt, die mit der problemzentrierten Methode nach Andreas Witzel erfasst und ausgewertet werden. Es zeigt sich, dass die Kommunikation in der Erfragung von Wohnwünschen und -träumen eine Kernkompetenz darstellt und eine sorgfältige Interpretation wichtig ist. Die Arbeit dient der Sensibilisierung von Professionellen der Sozialen Arbeit in unterschiedlichen Handlungsbereichen. Es werden dadurch neue Erkenntnisse, sowie kreative Ideen im Bereich Wohnen von Menschen mit einer kognitiven Behinderung, die in einer Institution leben, angeregt.
description: + Code Diss LU: hslusa basa 2016 + Fussnote: Ausbildungsgang Sozialarbeit
pyTANSPEC: A Data Reduction Package for TANSPEC
Creators: name: Ghosh, Supriyo
name: Ninan, Joe P.
name: Ojha, Devendra K.
name: Sharma, Saurabh
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The TIFR-ARIES Near Infrared Spectrometer (TANSPEC) instrument provides simultaneous wavelength coverage from 0.55 to 2.5 micron, mounted on India's largest ground-based telescope, 3.6-m Devasthal Optical Telescope at Nainital, India. The TANSPEC offers three modes of observations, imaging with various filters, spectroscopy in the low-resolution prism mode with derived R~ 100-400 and the high-resolution cross-dispersed mode (XD-mode) with derived median R~ 2750 for a slit of width 0.5 arcsec. In the XD-mode, ten cross-dispersed orders are packed in the 2048 x 2048 pixels detector to cover the full wavelength regime. As the XD-mode is most utilized as well as for consistent data reduction for all orders and to reduce data reduction time, a dedicated pipeline is at the need. In this paper, we present the code for the TANSPEC XD-mode data reduction, its workflow, input/output files, and a showcase of its implementation on a particular dataset. This publicly available pipeline pyTANSPEC is fully developed in Python and includes nominal human intervention only for the quality assurance of the reduced data. Two customized configuration files are used to guide the data reduction. The pipeline creates a log file for all the fits files in a given data directory from its header, identifies correct frames (science, continuum and calibration lamps) based on the user input, and offers an option to the user for eyeballing and accepting/removing of the frames, does the cleaning of raw science frames and yields final wavelength calibrated spectra of all orders simultaneously.
description: 10 pages, 6 figures, accepted for publication in the Special Issue of Journal of Astrophysics & Astronomy, 2022, Star formation studies in context of NIR instruments on 3.6m DOT, held at ARIES, Nainital during 4-7, May, 2022
Extracting the sample response function from experimental two-dimensional terahertz-infrared-visible spectra
Creators: name: Seliya, Pankaj
name: Bonn, Mischa
name: Grechko, Maksim
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Terahertz molecular motions are often probed by high-frequency molecular oscillators in different types of non-linear vibrational spectroscopy. Recently developed two-dimensional terahertz-infrared-visible spectroscopy allows direct measuring of this coupling and, thus, obtaining site-specific terahertz vibrational spectrum. However, these data are affected by the intensity and phase of the employed laser pulses. In this work, we develop a method of extracting sample response - representing solely physical properties of a material - from experimental spectra. Using dimethyl sulfoxide (DMSO) as a model molecule to verify this method, we measure the coupling between C-H stretch vibration of its methyl groups and terahertz intramolecular twist and wagging modes.
Helical buckling of Skyrme-Faddeev solitons
Creators: name: Foster, David
name: Harland, Derek
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 70S20, 74G60

description: Solitons in the Skyrme-Faddeev model on R^2xS^1 are shown to undergo buckling transitions as the circumference of the S^1 is varied. These results support a recent conjecture that solitons in this field theory are well-described by a much simpler model of elastic rods.
description: 24 pages, 9 figures
On the Asymptotic Capacity of Information Theoretical Privacy-preserving Epidemiological Data Collection
Creators: name: Cheng, Jiale
name: Liu, Nan
name: Kang, Wei
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We formulate a new secure distributed computation problem, where a simulation center can require any linear combination of $ K $ users' data through a caching layer consisting of $ N $ servers. The users, servers, and data collector do not trust each other. For users, any data is required to be protected from up to $ E $ servers; for servers, any more information than the desired linear combination cannot be leaked to the data collector; and for the data collector, any single server knows nothing about the coefficients of the linear combination. Our goal is to find the optimal download cost, which is defined as the size of message uploaded to the simulation center by the servers, to the size of desired linear combination. We proposed a scheme with the optimal download cost when $E < N-1$. We also prove that when $E\geq N-1$, the scheme is not feasible.
Importance sampling for stochastic quantum simulations
Creators: name: Kiss, Oriel
name: Grossi, Michele
name: Roggero, Alessandro
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Simulating many-body quantum systems is a promising task for quantum computers. However, the depth of most algorithms, such as product formulas, scales with the number of terms in the Hamiltonian, and can therefore be challenging to implement on near-term, as well as early fault-tolerant quantum devices. An efficient solution is given by the stochastic compilation protocol known as qDrift, which builds random product formulas by sampling from the Hamiltonian according to the coefficients. In this work, we unify the qDrift protocol with importance sampling, allowing us to sample from arbitrary probability distributions, while controlling both the bias, as well as the statistical fluctuations. We show that the simulation cost can be reduced while achieving the same accuracy, by considering the individual simulation cost during the sampling stage. Moreover, we incorporate recent work on composite channel and compute rigorous bounds on the bias and variance, showing how to choose the number of samples, experiments, and time steps for a given target accuracy. These results lead to a more efficient implementation of the qDrift protocol, both with and without the use of composite channels. Theoretical results are confirmed by numerical simulations performed on a lattice nuclear effective field theory.
description: 17 pages, 9 pages supplemental material
Frozen Mode Regime in an Optical Waveguide With Distributed Bragg Reflector
Creators: name: Furman, Nathaniel
name: Mealy, Tarek
name: Islam, Md Shafiqul
name: Vitebskiy, Ilya
name: Gibson, Ricky
name: Bedford, Robert
name: Boyraz, Ozdal
name: Capolino, Filippo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We introduce a glide symmetric optical waveguide exhibiting a stationary inflection point (SIP) in the Bloch wavenumber dispersion relation. An SIP is a third order exceptional point of degeneracy (EPD) where three Bloch eigenmodes coalesce to form a so-called frozen mode with vanishing group velocity and diverging amplitude. We show that the incorporation of chirped distributed Bragg reflectors and distributed coupling between waveguides in the periodic structure facilitates the SIP formation and greatly enhances the characteristics of the frozen mode regime. We confirm the existence of an SIP in two ways: by observing the flatness of the dispersion diagram and also by using a coalescence parameter describing the separation of the three eigenvectors collapsing on each other. We find that in the absence of losses, both the quality factor and the group delay at the SIP grow with the cubic power of the cavity length. The frozen mode regime can be very attractive for light amplification and lasing, in optical delay lines, sensors, and modulators.
description: 11 pages, 14 figures
The fate of non-supersymmetric Gross-Neveu-Yukawa fixed point in two dimensions
Creators: name: Nakayama, Yu
name: Kikuchi, Ken
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Category Theory (math.CT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We investigate the fate of the non-supersymmetric Gross-Neveu-Yukawa fixed point found by Fei et al in $4-ε$ dimensions with a two-component Majorana fermion continued to two dimensions. Assuming that it is a fermionic minimal model which possesses a chiral $\mathbb{Z}_2$ symmetry (in addition to fermion number parity) and just two relevant singlet operators, we can zero in on four candidates. Assuming further that the least relevant deformation leads to the supersymmetric Gross-Neveu-Yukawa fixed point (i.e. fermionic tricritical Ising model), we can rule out two of them by matching the spin contents of the preserved topological defect lines. The final candidates are the fermionic $(11,4)$ minimal model if it is non-unitary, and the fermionic $(E_{6}, A_{10})$ minimal model if it is unitary. If we further use a constraint from the double braiding relation proposed by one of the authors, the former scenario is preferable.
description: 24 pages + Appendices; v2: version accepted by JHEP
Mycetophila marginata Winnertz 1864
Creators: name: El Mouden, Mohamed Amin
name: Chandler, Peter J.
name: Saidoun, Imane
name: Driauach, Ouafaa
name: Belqat, Boutaïna
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Mycetophilidae
Mycetophila
Mycetophila marginata

description: Mycetophila marginata Winnertz, 1864
Material examined.
Morocco – Middle Atlas Region • 21 ♂♂, 51 ♀♀; Gouffre Izora; 19/V/2022; K. Aattouch, M. El Ouahabi and M. A. El Mouden leg; UAE-FST MA 22/24140 • 32 ♂♂; Grotte Bouslama; 19/V/2022; K. Aattouch, M. El Ouahabi and M. A. El Mouden leg; UAE-FST MA 22/24141 • 1 ♂; Vallée des oiseaux; 19/V/2022; K. Aattouch, M. El Ouahabi and M. A. El Mouden leg; UAE-FST MA 22/24142 • 1 ♂; Grotte Bouhayati; 20/V/2022; K. Aattouch, M. El Ouahabi and M. A. El Mouden leg; UAE-FST MA 22/24143.
North African distribution.
Morocco (Banamar et al. 2020).
description: Published as part of El Mouden, Mohamed Amin, Chandler, Peter J., Saidoun, Imane, Driauach, Ouafaa & Belqat, Boutaïna, 2025, A new species of Docosia Winnertz, 1864 and new records of fungus gnats (Diptera, Bolitophilidae, Keroplatidae and Mycetophilidae) from North Africa, pp. 349-379 in ZooKeys 1233 on pages 349-379, DOI: 10.3897/zookeys.1233.130502
X-ray variability of 104 active galactic nuclei. XMM-Newton power-spectrum density profiles
Creators: name: Gonzalez-Martin, O.
name: Vaughan, S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: AGN, powered by accretion onto SMBHs, are thought to be scaled up versions of Galactic black hole X-ray binaries (BH-XRBs). In the past few years evidence of such correspondence include similarities in the broadband shape of the X-ray variability power spectra, with characteristic bend times-scales scaling with mass. We have performed a uniform analysis of the power spectrum densities (PSDs) of 104 nearby (z<0.4) AGN using 209 XMM-Newton/pn observations. The PSDs have been estimated in three energy bands: 0.2-10, 0.2-2, and 2-10 keV. The sample comprises 61 Type-1 AGN, 21 Type-2 AGN, 15 NLSy1, and 7 BLLACS. We have fitted each PSD to two models: (1) a single power-law model and (2) a bending power-law model. Among the entire sample, 72% show significant variability in at least one of the three bands tested. A high percentage of low-luminosity AGN do not show any significant variability. The PSD of the majority of the variable AGN was well described by a simple power-law with a mean index of 2. In 15 sources we found that the bending power law model was preferred with a mean slope of 3 and a mean bend frequency of 2.E-04 Hz. Only KUG1031+398 (REJ1034+396) shows evidence for quasi-periodic oscillations. The `fundamental plane' relating variability timescale, black hole mass, and luminosity is demonstrated using the new X-ray timing results presented here together with a compilation of the previously detected timescales from the literature. Both quantitative (i.e. scaling with BH mass) and qualitative (overall PSD shapes) found in this sample of AGN are in agreement with the expectations for the SMBHs and BH-XRBs being the same phenomenon scaled-up with the size of the BH. The steep PSD slopes above the high frequency bend bear a closer resemblance to those of the `soft/thermal dominated' BH-XRB states than other states.
description: 19 pages, 8 figures, accepted for publication in A&A
Non-local correlation effects due to virtual spin-flip processes in itinerant electron ferromagnets
Creators: name: Paischer, S.
name: Vignale, G.
name: Katsnelson, M. I.
name: Ernst, A.
name: Buczek, P.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present an ab initio method for eletcronic structure calculations, which accounts for the interaction of electrons and magnons in ferromagnets. While it is based on a many body perturbation theory we approximate numerically complex quantities with quantities from time dependent density functional theory. This results in a simple and affordable algorithm which allows us to consider more complex materials than those usually studied in this context ($3d$ ferromagnets) while still being able to account for the non-locality of the self energy. Furthermore, our approach allows for a relatively simple way to incorporate self-consistency. Our results are in a good agreement with experimental and theoretical findings for iron and nickel. Especially the experimental exchange splitting of nickel is predicted accurately within our theory. Additionally, we study the halfmetallic ferromagnet NiMnSb concerning its non-qusiparticle states appearing in the bandgap due to spin-flip excitations.
Landslide runout: statistical analysis of physical characteristics and model parameters
Creators: name: McKinnon, Mika
Publisher: name: University of British Columbia
Year: 2010

description: Landslides are treacherous, but risk management actions based on improved prediction of landslide runout can reduce casualties and damage. Forty rapid flow-like landslides of variable volume, entrainment, and composition are used to develop a volume-runout regression, which is compared to those established in previous research. The cases are analyzed to identify the most critical characteristics observable prior to failure which differentiate between events of high and low mobility. Mitigating long-runout flow-like landslides requires accurate hazard mapping, a task best accomplished through runout modelling. Current practice requires back-analyzing a set of cases consistent in scope with the target event, then applying the same rheology and parameters to forward modelling. This thesis determines which aspects of scope are most important to prioritize when selecting similar cases, as volume, movement type, morphology, and material have a more substantial influence on mobility than other physical characteristics. Statistical analysis of the performance of frictional and Voellmy rheologies over a range of parameters for the forty case studies provides the expected mean normalized runout and associated standard deviation, and recommendations for parameters to use in initial forward modelling of prospective events.
Aloin A inhibits SARS CoV-2 replication by targeting its binding with ACE2 - Evidence from modeling-supported molecular dynamics simulation
Creators: name: Alhadrami, Hani A.
name: Sayed, Ahmed M.
name: Hassan, Hossam M.
name: Rateb, Mostafa E.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: The current study aimed to expand on the recently published results and assess the inhibitory efficacy of aloin A against SARS CoV-2. In vitro testing of aloin A against SARS CoV-2 proteases (i.e., MPro and PLPro) showed weak to moderate activity (IC50 = 68.56 ± 1.13 µM and 24.77 ± 1.57 µM, respectively). However, aloin A was able to inhibit the replication of SARS CoV-2 in Vero E6 cells efficiently with an IC50 of 0.095 ± 0.022 µM. Depending on the reported poor permeability of aloin A alongside its insignificant protease inhibitory activities presented in this study, we ran a number of extensive virtual screenings and physics-based simulations to determine the compound’s potential mode of action. As a result, RBD-ACE2 was identified as a key target for aloin A. Results from 600 ns-long molecular dynamics (MD) simulation experiments pointed to aloin A's role as an RBD-ACE2 destabilizer. Therefore, the results of this work may pave the way for further development of this scaffold and the eventual production of innovative anti-SARS CoV-2 medicines with several mechanisms of action. Communicated by Ramaswamy H. Sarma
Supersymmetric solutions of type-II supergravity from $λ$-deformations and zoom-in limits
Creators: name: Itsios, Georgios
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct the embedding of the $λ$-model on $SL(2, \mathbb{R}) \times SU(2) \times SU(2)$ in type-II supergravity. In the absence of deformation, the ten-dimensional background corresponds to the near-horizon limit of the NS1-NS5-NS5 brane intersection. We show that when the deformation is turned on, supersymmetry breaks by half, and the solution preserves 8 supercharges. The Penrose limits along two null geodesics of the deformed geometry are also considered. It turns out that none of the associated plane-wave backgrounds exhibit supernumerary supercharges.
description: 30 pages, 1 figure, JHEP version