cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Eye Movements as Indicators of Deception: A Machine Learning Approach
Creators: name: Foucher, Valentin
name: de Leon-Martinez, Santiago
name: Moro, Robert
Publisher: name: arXiv
Year: 2025
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Gaze may enhance the robustness of lie detectors but remains under-studied. This study evaluated the efficacy of AI models (using fixations, saccades, blinks, and pupil size) for detecting deception in Concealed Information Tests across two datasets. The first, collected with Eyelink 1000, contains gaze data from a computerized experiment where 87 participants revealed, concealed, or faked the value of a previously selected card. The second, collected with Pupil Neon, involved 36 participants performing a similar task but facing an experimenter. XGBoost achieved accuracies up to 74% in a binary classification task (Revealing vs. Concealing) and 49% in a more challenging three-classification task (Revealing vs. Concealing vs. Faking). Feature analysis identified saccade number, duration, amplitude, and maximum pupil size as the most important for deception prediction. These results demonstrate the feasibility of using gaze and AI to enhance lie detectors and encourage future research that may improve on this.
Roses of Love, Violets of Humility and Lilies of Suffering: A Phenomenological Hermeneutic Study of Floral Experiences in the Diary of St. Faustina Kowalska (1905-1938)
Creators: name: Kandler, Renate
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Catholic
Faustina
Saint
Mystic
Phenomenology
Hermeneutic
Polish
lifeworld
body
time
space
Flower
Rose
Violet
Lily

description: The presence of flowers is felt in Catholic architecture, literature, artwork, personal histories and devotional practices. This, however, has not always been the case. The Catholic Church has had a long and tumultuous relationship with flowers, the focus of which has been the subject of considerable scholarship (e.g. Fisher (2011, 2007), Ward (1999), Winston-Allen (1997), Goody (1993), Coats (1970)). What has not been much considered is a phenomenological treatment of Catholic floral experience, and how such experiences have shaped individual and shared understandings of the Catholic faith. This thesis seeks to redress this omission through an exploration of the life of the Polish Catholic mystic, St. Faustina Kowalska (1905-1938), whose mystical experiences with the divine were explicitly mediated and narrated through flowers. Through Faustina’s diary, Divine Mercy in my Soul, we gain access to powerful, and unequivocally Catholic, experiences with flowers which comprise the very centre of her religious convictions. This thesis queries the ways in which flowers have dynamically shaped, and have been shaped by, St. Faustina's relationship with God and Catholic holy figures. To address this question I use the semiotic, phenomenological and hermeneutic approach of Max van Manen. Van Manen uses four elements of lived experience he calls lifeworld existentials, these are: lived space, lived time, lived body and lived relationality. These four categories are applied to St. Faustina’s life as she engages with God spatially, temporally, corporeally and relationally; each reveals the centrality of flowers in her religious experiences. While this thesis focuses on the religio-floral experiences of a particular mystic-saint, its significance lies also in the broader Catholic narrative of which it is a part. Writing about flowers was a transformative medium in Faustina's life and has been historically significant in the lives of many other Catholic saints and mystics who recorded similar experiences. This thesis, in describing the details of St. Faustina’s floral-saturated experiences from her diary, reveals a particularized instance of a paradigmatic Catholic phenomenon whereby flowers provide access to the sacred.
Impacts of Retrogressive Thaw Slumps on the Geochemistry of Permafrost Catchments, Stony Creek Watershed, NWT
Creators: name: Malone, Laura
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: retrogressive thaw slump
periglacial streams
geochemistry
Richardson Mountains

description: Retrogressive thaw slumps are one of the most dramatic thermokarst landforms in periglacial regions. This thesis investigates the impacts of two of the largest hillslope thaw slumps on the geochemistry of periglacial streams on the Peel Plateau, Northwest Territories. It aims to describe the inorganic geochemistry of runoff across active mega-slumps, impacted and pristine tundra streams, as well as that of the ice-rich permafrost exposed in the slump headwalls. Slump runoff is characterized by elevated suspended sediments (911 g/L), high conductivity (2700 µS/cm), and high SO42- ( up to 2078 ppm). The runoff originates as a solute-rich meltwater near the slump headwall, and leaches and re-dissolves soluble salts (e.g., gypsum) as it flows along the mudflow. Conductivity increases until the runoff mixes with pristine tundra streams, diluting the slump runoff signal. SO42-/Cl- is used as a tracer to isolate the slump runoff signal in impacted waters, and suggests that the contribution of slump runoff to the Peel River has been increasing since the 1960s.
New Challenges in Teaching Accounting and Reporting in Tourist Enterprises
New Challenges in Teaching Accounting and Reporting in Tourist Enterprises
Creators: name: Baldarelli, Maria Gabriella; University Of Bologna
Publisher: name: Campus di Rimini - Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: tourist enterprises; teaching; accounting; SEAR; tourism

description: The experience of teaching for several years in different degree courses pressed me to use new tools and methods to make use of Connecting general trend of teaching all over the world this paper want to reply to the following research question: “what challenges we are facing in teaching accounting and reporting in tourist enterprises?”.Research design is oriented to deep study international literature about the state of art of teaching accounting and above all social and environmental accounting and reporting (SEAR)(Gray, Owen, Adams, 1996, Tinker, Gray, 2003; Tinker, 2005; Gray, Guthrie, 2007), because I think that this field is very important for service enterprises, especially for tourist ones. The importance is given by disclosure and democracy that is at the base of SEAR process and my interest to safeguard people and environment in tourist entities and destinations (Garrone, Di Cesare, 2005).I want to present some reflections about how to teach accounting in tourism to give student the availability to understand the constructive role of accounting but at the same time the bad role of it at the same to serve power and exploitation.
description: The experience of teaching for several years in different degree courses pressed me to use new tools and methods to make use of Connecting general trend of teaching all over the world this paper want to reply to the following research question: “what challenges we are facing in teaching accounting and reporting in tourist enterprises?”.Research design is oriented to deep study international literature about the state of art of teaching accounting and above all social and environmental accounting and reporting(SEAR)( Gray, Owen, Adams, 1996, Tinker, Gray, 2003; Tinker, 2005; Gray, Guthrie, 2007), because I think that this field is very important for service enterprises, especially for tourist ones. The importance is given by disclosure and democracy that is at the base of SEAR process and my interest to safeguard people and environment in tourist entities and destinations ( Garrone, Di Cesare, 2005).I want to present some reflections about how to teach accounting in tourism to give student the availability to understand the constructive role of accounting but at the same time the bad role of it at the same to serve power and exploitation.
description: Almatourism - Journal of Tourism, Culture and Territorial Development; Vol 3, No 6 (2012); 1-15
A Structural Equation Modelling for Crm Development  in Rural Tourism in the Catalan Pyrenees
Un Modelo de Ecuaciones Estructurales Para el Desarrollo del Crm en el Turismo Rural en los Pirineos Catalanes
Creators: name: Prat Forga, José Mª; Autonomous University Of Barcelona
Publisher: name: Campus di Rimini - Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: rural tourism; customer relationship management; teleworkers; structural equation modelling; Catalonia

description: This paper investigates the interrelationships between customer relationship management development in rural tourism, information and communication technologies level in the territory, perceived economic impacts and rural tourism development. A total of 76 respondents completed a survey conducted in the Spanish Pyrenees Mountains in order to examine the structural effects of these impact factors. The results reveal that the support for customer relationship management development in rural tourism shown by rural tourism workers mainly depends on the level of development of information and communication technologies. A confirmatory factor analysis and structural equation modelling procedure were performed, respectively, using the AMOS software.
description: Este artículo investiga las relaciones existentes entre el desarrollo de la gestión de relaciones de clientes (CRM) en el turismo rural, el nivel de uso de las tecnologías de la información y comunicación (TIC) en dicho territorio,  los impactos económicos percibidos por el uso del CRM y el propio desarrollo del turismo rural. Para ello, se ha realizado una encuesta a 76 entrevistados en las montañas de los Pirineos en Cataluña (España), con el objetivo de analizar los efectos estructurales de estos factores de impacto. Los resultados obtenidos revelan que el soporte para el desarrollo del CRM en el turismo rural muestra que su uso por los trabajadores empleados en este sector depende principalmente del nivel de desarrollo de las TIC en el territorio. Para confirmar esta hipótesis, se ha diseñado un modelo de ecuaciones estructurales (SEM) y, posteriormente, se ha ejecutado un análisis factorial confirmatorio (CFA) a dicho modelo, mediante el software AMOS 5.
description: Almatourism - Journal of Tourism, Culture and Territorial Development; Vol 3, No 6 (2012); 16-39
The “Touring Club Italiano” and the Pride for the Army from 1908 to 1914
The “Touring Club Italiano” and the Pride for the Army from 1908 to 1914
Creators: name: Bizzocchi, Marco; University Of Bologna
Publisher: name: Campus di Rimini - Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: Touring Club Italiano; army; nationalism; military industry; technological progress

description: Announced on December 1907 and completed in January of the following year, the Touring Club Italiano update aesthetic and substance of its official propaganda organ: “Rivista mensile del Touring Club Italiano”. In a detailed analysis of the review we want demonstrate that with this aesthetic update there is a tacit, but clear, change of direction of the whole association that opens to a nationalistic thought.
description: Announced on December 1907 and completed in January of the following year, the Touring Club Italiano update aesthetic and substance of its official propaganda organ: “Rivista mensile del Touring Club Italiano”. In a detailed analysis of the review we want demonstrate that with this aesthetic update there is a tacit, but clear, change of direction of the whole association that opens to a nationalistic thought.
description: Almatourism - Journal of Tourism, Culture and Territorial Development; Vol 3, No 6 (2012); 40-49
Sim2Real in endoscopy segmentation with a novel structure aware image translation
Creators: name: Tomasini, Clara
name: Riazuelo, Luis
name: Murillo, Ana C.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences
subject: I.2.10; I.4.6

description: Automatic segmentation of anatomical landmarks in endoscopic images can provide assistance to doctors and surgeons for diagnosis, treatments or medical training. However, obtaining the annotations required to train commonly used supervised learning methods is a tedious and difficult task, in particular for real images. While ground truth annotations are easier to obtain for synthetic data, models trained on such data often do not generalize well to real data. Generative approaches can add realistic texture to it, but face difficulties to maintain the structure of the original scene. The main contribution in this work is a novel image translation model that adds realistic texture to simulated endoscopic images while keeping the key scene layout information. Our approach produces realistic images in different endoscopy scenarios. We demonstrate these images can effectively be used to successfully train a model for a challenging end task without any real labeled data. In particular, we demonstrate our approach for the task of fold segmentation in colonoscopy images. Folds are key anatomical landmarks that can occlude parts of the colon mucosa and possible polyps. Our approach generates realistic images maintaining the shape and location of the original folds, after the image-style-translation, better than existing methods. We run experiments both on a novel simulated dataset for fold segmentation, and real data from the EndoMapper (EM) dataset. All our new generated data and new EM metadata is being released to facilitate further research, as no public benchmark is currently available for the task of fold segmentation.
Étude sociolinguistique du français acadien du nord-est du Nouveau-Brunswick
Creators: name: Chiasson-Léger, Mélissa
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: sociolinguistique
français acadien
variation
accord sujet-verbe à la troisième personne du pluriel
emprunts à l'anglais

description: Cette étude porte sur le français acadien du nord-est du Nouveau-Brunswick en adoptant l’approche de la sociolinguistique variationniste (Labov, 1966, 1969, 1971, 1982, 1984). L’étude est basée sur 16 entrevues sociolinguistiques recueillies en 2013 à Caraquet et à St-Simon, deux municipalités dans la Péninsule acadienne. Le corpus est entre autres stratifié selon le réseau social, le sexe, l’âge des locuteurs afin d’explorer le conditionnement social et linguistique des variables ciblées par l’étude et de repérer des changements potentiels en cours par le biais des analyses effectuées en temps apparent. Les objectifs principaux de la recherche sont de découvrir le fonctionnement de la grammaire sous-jacente du français acadien en menant une étude empirique et quantitative sur la variabilité sociolinguistique de deux variables morphosyntaxiques : (i) l’expression du futur et (ii) l’accord sujet-verbe de la troisième personne du pluriel. Pour ce qui est du futur, le Nouveau-Brunswick est la seule province à ne pas avoir été étudiée d’un point de vue sociolinguistique. Les résultats viennent alors compléter le portrait dressé sur le futur de quatre régions de chacune des provinces atlantiques (King et Nadasdi, 2003 ; Comeau, 2011) et montrent comment le futur en français acadien du Nouveau-Brunswick se comporte par rapport à celui des provinces voisines considérées comme conservatrices. Sur le plan de l’accord sujet-verbe de la troisième personne du pluriel, les résultats de cette étude sont comparés à celles menées avec des données datant d’il y a environ 25 ans (Beaulieu, 1995) d’une région voisine pour entre autres vérifier si les taux sont semblables ou à la baisse et voir si d’autres facteurs que le réseau social joue un rôle dans le maintien de la flexion. Un troisième domaine a aussi été étudié : les emprunts à l’anglais. L’analyse quantitative des emprunts dans un contexte francophone majoritaire permet d’examiner ce qui est emprunté, la fréquence et comment les emprunts sont intégrés dans la langue des locuteurs. Cette étude permet aussi de vérifier si la croyance populaire que le français canadien serait truffé d’anglicismes est fondée ou non.
title: Open data for all
title: The role of civil society in Germany
titleType: Subtitle
Creators: name: Wiedemann, Mario
name: Paderta, Damian
name: Hauser, Nina
name: Klug, Petra
name: Frerichs, Mila
Publisher: name: Bertelsmann Stiftung
publisherIdentifier: https://ror.org/01wj9hk44
publisherIdentifierScheme: ROR
Year: 2024
Subjects: Open data
Civil Society
Data Ecosystem

description: Which initiatives would be required to expand the pool of data from civil society and create an open data ecosystem? The Bertelsmann Stiftung’s Data for Society project has explored the potential that open data from civil society has to offer. A new discussion paper summarizes the findings from numerous workshops and dialogues.

In the best-case scenario, a diverse data ecosystem is supported by a range of civil society stakeholders. That allows it to serve as a catalyst for social change while increasing transparency, social innovation and democratic participation.

In its exploratory project Open Data and Civil Society, the Bertelsmann Stiftung has organized several workshops and multiple discussions with civil society stakeholders since 2022 to examine the potential that open data from civil society has to offer. The new discussion paper “Open Data for All: The Role of Civil Society” summarizes the findings from these activities.
SHP-1/ Src Complex is a Master Regulator of the IL-12/IL-23 pro- and IL-10/IL-27 Anti-inflammatory Axis in TLR4-activated Signaling Pathways in Human Monocytes and Macrophages
Creators: name: Konarski, Yulia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: SHP-1
subject: Src
subject: IL-12 family
subject: IL-10
subject: Autoimmune Diseases

description: Although the etiology surrounding many autoimmune diseases remains unknown, the underlying characteristic of many of these diseases is a disruption in the balance of pro- and anti- inflammatory cytokines It is well established that the dysregulation of the IL-12 family of cytokines, an increase in IL-12/IL-23 and a decrease in IL-27 production has been implicated in these conditions. We used ELISA, RT-PCR, Immunofluorescence and Western immunoblotting in conjunction with pharmalogical inhibitors and siRNA to demonstrate the role of SHP-1/Src in the regulation of IL-12, IL-23, IL-27 and IL-10 in LPS-stimulated human THP-1 cells, monocytes and MDMs. My results show for the first time that Src kinase activity relies on SHP-1 activity, and together this complex functions in TLR4-mediated MyD88 and TRIF pathways. Furthermore Src exhibits a dual role as a positive regulator for anti-inflammatory IL-10/IL-27 and as a negative regulator of pro-inflammatory IL-12/IL-23 downstream of TLR4. Moreover, the involvement of PI3K and JNK MAPK, dependent on SHP-1/Src complex, in the regulation of IL-12 family and IL-10 downstream of TLR4 was shown.
Efficient Mechanisms for Exploration of Dangerous Graphs and for Inter-agent Communication
Creators: name: Balamohan, Balasingham
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Black Hole
Dangerous Graph
Token
Exploration
Map Construction

description: This thesis deals with the problems of exploration and map construction of a dangerous network by mobile agents, and it introduces new general mechanisms for inter-agent communication, which could be applied to other mobile agents' problems. A dangerous network contains a harmful process called Black Hole that destroys all agents entering the node where it resides, without leaving any observable trace. The task for the agents, which are moving asynchronously, is to construct a map of the network with edges incident on the black hole unambiguously identified. Two types of communication mechanisms are considered: whiteboards and tokens. In the whiteboard model every node provides a shared memory on which agents can read and write. When communication occurs through tokens, instead, the agents have some pebbles that can be placed on and picked up from the nodes. Four different costs for comparing the efficiency of the protocols are taken into account: the number of agents required, the number of moves performed, the size of the whiteboard (or the token capacity at a node), and time. The black hole search problem is considered first in ring networks with whiteboards, and optimal exact time and move complexities are established improving all existing results. The same problem is then studied in arbitrary unknown graphs and it is solved in the token model by using a constant number of tokens in total. The protocol improves on existing results and is based on a novel technique for communicating using tokens. Finally, the new method of communicating using tokens described in the context of black hole search is generalized to propose a novel communication mechanism among the agents that could possibly be employed for any distributed algorithm by mobile agents.
Reactivity of Chromium with Aluminates: The Quest for Monovalent Chromium Complexes
Creators: name: HajiAli Afzali, Saba
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013

description: Progress in catalytic ethylene oligmerization and polymerization processes creates an enormously valuable and active field in both industry and academic perspective. From the naive point of view, gathering ethylene molecules to generate carbon carbon bonds can be assumed as the no electron, no energy and facile chemical process which results from interaction of several π-electrons but this process never can afford macro- and micromolecule without applying catalysts. It is no wonder that major efforts have been committed to designing novel catalysts to perform poly- and oligomerization processes, both recently and in the past which provide the extensive library of catalysts today. Among all the metals applied in preparation of homogeneous catalysts for ethylene oligo- and polymerization, chromium has been ideal in providing versatile systems in terms of selectivity and activity for oligomer and polymer productions. In the first part of the current work we chose two different ligand systems (iminopyridine and bisiminophosphine) to investigate the activity of their chromium complexes for ethylene oligmerization and polymerization at different conditions. In addition we took on the substantial challenge of explaining the activities through isolation of intermediates during the catalytic runs. The major focus in this part was rationalizing catalytic behaviour of the catalysts through elucidation of metal oxidation state. To fulfill this goal, syntheses of chromium-aluminate complexes in different valence states as well as description ligand-metal interactions were presented. In the second part of this thesis, our mainly focus of study was on the development in the well- established field of radical chemistry of alkylaluminum. Preferential cation radical and diradical formation and exploring their stabilities through both experimental and computational methods will be discussed. Also continuation of this work led us to report unprecedented double alkylation on the ligand system.
Supplementary document for Influence of anatomical features of different brain regions on the spatial localization of fiber photometry signals - 5425780.pdf
Creators: name: Montinaro, Cinzia
name: Pisanello, Marco
name: Bianco, Marco
name: Spagnolo, Barbara
name: Pisano, Filippo
name: Balena, Antonio
name: De Nuccio, Francesco
name: Lofrumento, Dario Domenico
name: Verri, Tiziano
name: De Vittorio, Massimo
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
Anal Fistula - Basics and Management
Creators: name: Ali, Sajjad
name: Memon, Hassan Ali
Publisher: name: Zenodo
Year: 2020
Subjects: Anal Fistula
Treatment
Management
Anal Sphincter
Fecal Incontinence

description: A fistula-in-ano is an epithelial-lined tract connecting the anal canal to the perianal skin. Anal fistulas can have many causes but are most commonly the result of an anorectal abscess. Classification of the fistula is determined in relation to the anal sphincters. Although benign, the condition can cause significant distress and embarrassment to the patient. Treatment focuses on control of the infection and maintaining fecal continence. Many treatment options are available, and novel treatments are steadily proposed and tested. This presentation will review the fundamental principles of fistula-in-ano diagnosis and treatment.
The EU Ineffective Counterterrorism Strategy
Creators: name: Marsili, Marco
Publisher: name: Zenodo
Year: 2017
Subjects: Terrorism, European Union (EU), Europe, Security, Islam

description: The European Union security and counter-terrorism strategy adopted after 11 September 2001 has not been effective, instead resulted in the increase of Islamist terrorist incidents. Europe has been hit by a wave of terrorist attacks, which demonstrates the limits of the Security and Defence Policy. The EU short-term strategy, tending only to hit terrorist organisations, has not produced the expected effects: attacks in Europe, rather than decreasing, have increased. Little or nothing has been done to develop a successful preventive strategy. After the early 2000s, there is hardly registered Islamic attack within the EU, due to the change in the Al-Qaeda strategy. The recrudescence recorded after 2014 coincides with the rise of ISIS. The EU shortsighted strategy adopted so far to combat Islamic terrorism has proved ineffective. Attacks within the EU, rather than decreasing, have increased. The high number of terrorist incidents and casualties within the EU demonstrates that terrorism can not be stopped only with criminal provisions, freezing of assets and financial resources, blocking immigration and strengthening of border controls. Only a long-term cultural strategy, adequately funded, can be effective to counter terrorism.
description: Poster presented at Encontro Ciência 2017 (National Cience Summit 2017), the Science and Technology Summit in Portugal, held at Lisbon Congress Centre, Lisboa, Portugal, 3-5 July 2017 Seminal research has been presented at the international conference Europe as a Global Actor (EGA) 2016 in Lisbon on 24 May 2016. See: "A Critical Assessment of the European Cultural Approach to Counter Terrorism" (DOI: 10.5281/zenodo.810533)
Increasing military capability through information and communication
Creators: name: Marsili, Marco
Publisher: name: Zenodo
Year: 2016
Subjects: NATO
North Atlantic Treaty Organization
CMRE (Centre for Maritime Research and Experimentation)
Military capability
Stakeholders
Policymakers
Decision-makers
Information representation
Information visualization
Information communication

description: The scope of this abstract is to pursue and increase the quality levels of the military instrument to enhance the effectiveness, operational capabilities and overall employability by providing a timely information representation and a catchy and tailored visualization and communication support. The impact of information and communication on civilian/military maritime operations should be addressed in a social and political perspective. The success of communication, both indoor and outdoor, is essential for achieving goals. A fully-informed and favorable outdoor and indoor environment supports and facilitates the achievement of military objectives. Communication must be multimedia, multiplatform and multilevel. Communication to be strength, must represent information in a simply and clear way through short text elements integrated with interactive visual representations: they capture at best the audience attention, without compromising the efficacy of the information content to be transmitted. Online availability through user-friendly and intuitive interface, enabling a positive user experience, is strongly recommended. Language should be natural for not military audience, and glossary should be available. Information should be manually categorized for not military audience. Communication results should be measured through a validation and verification process.
description: Presentation at the Decision Support and Risk Assessment for Operational Effectiveness (DeSRA) 2016 Conference held on 26-28 July hosted at NATO's Science and Technology Organization (STO)-Centre for Maritime Research and Experimentation (CMRE) in La Spezia, Italy
Associations between Neighborhood Walkability, Physical Activity, and Chronic Disease in Nova Scotian Adults: An Atlantic PATH Cohort Study
Creators: name: Keats, Melanie R.
name: Cui, Yunsong
name: DeClercq, Vanessa
name: Grandy, Scott A.
name: Sweeney, Ellen
name: Dummer, Trevor J. B.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2020

description: Background: While neighborhood walkability has been shown to positively influence health behaviors, less is known about its impact on chronic disease. Our aim was to examine the association between walkability and self-reported physical activity in relation to chronic health conditions in an Atlantic Canadian population. Methods: Using data from the Atlantic Partnership for Tomorrow’s Health, a prospective cohort study, we employed both a cross-sectional and a prospective analytical approach to investigate associations of walkability and physical activity with five prevalent chronic diseases and multimorbidity. Results: The cross-sectional data show that participants with the lowest neighborhood walkability were more likely to have reported a pre-existing history of cancer and depression and least likely to report chronic respiratory conditions. Participants with low physical activity were more likely to have a pre-existing history of diabetes, chronic respiratory disease, and multimorbidity. Follow-up analyses showed no significant associations between walkability and chronic disease incidence. Low levels of physical activity were significantly associated with diabetes, cancer and multimorbidity. Conclusions: Our data provides evidence for the health protective benefits of higher levels of physical activity, and a reduction in prevalence of some chronic diseases in more walkable communities.
Handbuch Lärmaktionspläne
Creators: name: Richard, Jochen
name: Mazur, Heinz
name: Lauenstein, Dirk
Publisher: name: My University
Year: 2015
Subjects: subject: Lärm
subject: Lärmschutz
subject: EU-Umgebungslärmrichtlinie
subject: Straßenverkehr
subject: Verkehrsplanung
subject: Aktiver Lärmschutz
subject: Automobilität
subject: Umgebungslärmrichtlinie
subject: Integrierte Verkehrsplanung
subject: Lärmbelastung
subject: Lärmkartierung
subject: Verkehr
subject: Transport
subject: Lärm

description: Im Handbuch werden die Grundlagen der EU-Umgebungslärmrichtlinie erläutert und Hinweise zur Auswertung der Lärmkarten gegeben. Schwerpunkt dieser Publikation bilden die Maßnahmen gegen den Straßenverkehrslärm. Diese werden hinsichtlich der Anwendungsmöglichkeiten und der Wirksamkeit detailliert zusammengestellt und bewertet. Weiterhin werden die rechtlichen Grundlagen zur Umsetzung von Minderungsmaßnahmen beleuchtet. Mit den Hinweisen zur Mitwirkung der Öffentlichkeit sowie zur Berücksichtigung des Schutzes ruhiger Gebiete liegen den zuständigen Behörden damit umfangreiche Informationen für eine erfolgreiche Lärmaktionsplanung vor.
Quelle: https://www.umweltbundesamt.de/
description: Im Handbuch werden die Grundlagen der EU-Umgebungslärmrichtlinie erläutert und Hinweise zur Auswertung der Lärmkarten gegeben. Schwerpunkt dieser Publikation bilden die Maßnahmen gegen den Straßenverkehrslärm. Diese werden hinsichtlich der Anwendungsmöglichkeiten und der Wirksamkeit detailliert zusammengestellt und bewertet. Weiterhin werden die rechtlichen Grundlagen zur Umsetzung von Minderungsmaßnahmen beleuchtet. Mit den Hinweisen zur Mitwirkung der Öffentlichkeit sowie zur Berücksichtigung des Schutzes ruhiger Gebiete liegen den zuständigen Behörden damit umfangreiche Informationen für eine erfolgreiche Lärmaktionsplanung vor.
Romosozumab: A Review in Postmenopausal Osteoporosis
Creators: name: Paik, Julia
name: Scott, Lesley J.
Publisher: name: Adis Journals
Year: 2020
Subjects: Medicine

description: Compliance with Ethical Standards Disclosure: The preparation of this review was not supported by any external funding. Conflicts of interest: Julia Paik and Lesley Scott are salaried employees of Adis/Springer, are responsible for the article content and declare no relevant conflicts of interest. Additional information about this Adis Drug Review can be found here Abstract Romosozumab (Evenity®), a humanized monoclonal antibody, promotes bone formation and inhibits bone resorption by inhibiting sclerostin, a protein involved in the regulation of bone formation. Subcutaneous romosozumab is approved in several countries, including those of the EU for treating severe osteoporosis as well as in the USA for osteoporosis in postmenopausal women at high risk of fracture. In pivotal phase III trials (FRAME and ARCH), 12 months’ once-monthly romosozumab 210 mg significantly reduced vertebral and clinical fracture risk versus placebo and oral alendronate in postmenopausal women with osteoporosis. After patients transitioned from romosozumab to 12–24 months of subcutaneous denosumab or oral alendronate, fracture risks were significantly improved versus placebo-to-denosumab and alendronate-only treatment. In these trials and a phase IIIb trial, romosozumab significantly increased bone mineral density (BMD) relative to placebo, alendronate and subcutaneous teriparatide at 12 months, with these benefits maintained 12–24 months after patients transitioned from romosozumab to alendronate or denosumab in pivotal trials. Romosozumab had a generally manageable tolerability profile. While further clinical experience is needed to more definitively establish its efficacy and safety, including its CV safety, romosozumab extends the treatment options in postmenopausal women with osteoporosis who have a high risk of fracture and in those who have failed or are intolerant to other available osteoporosis therapy. © Springer Nature Switzerland AG 2020
Sexual Conflict in Drosophila Serrata across Populations and Environments
Creators: name: Colpitts, Julie Ann
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: sexual conflict
Drosophila serrata

description: Earlier studies implicate interlocus sexual conflict as having important evolutionary consequences in Drosophila serrata but it has never been directly studied. I quantify sexual conflict and its divergence between two laboratory stocks using a full factorial manipulation of male population, female population, and level of male exposure to track longevity and fecundity of individual females. Evidence of strong sexual conflict, as well as divergence of male harm and female resistance between populations, was found. The relationship between environmental complexity and sexual conflict was then explored using a combination of behavioural observations and a factorial experiment to again track longevity and fecundity of individual females. Increased complexity was associated with decreased sexual activity and increased lifespan in females, although effects on fecundity were less clear. Overall, my studies combine to provide initial data for characterizing sexual conflict in Drosophila serrata and shed light on important considerations for its study.
Kinetic and thermodynamic characterization of the Mg–Fe–H system.
Creators: name: , J.Puszkiel
Publisher: name: Zenodo
Year: 2007
Subjects: hidrógeno
almacenamiento
hidruro complejo

description: En el presente estudio se llevó a cabo la síntesis del Mg2FeH6 por dos vías. A partir de una mezcla de polvos 2Mg – Fe, primero se aplicó la molienda mecánica en atmósfera de argón, seguida de una hidruración a alta temperatura y presión. Se obtuvo un material (MFI) compuesto por un 49 % p/p de Mg2FeH6. El otro método de síntesis empleado fue la molienda mecánica reactiva en atmósfera de hidrógeno, por medio de la cual no se logró sintetizar al Mg2FeH6 obteniéndose un material (MFHI) que sólo contenía β-MgH2. Las propiedades termodinámica de los materiales obtenidos fueron estudiadas mediante la medición de isotermas de absorción / desorción, a partir de las cuales se construyó el gráfico de van’t Hoff (Pequilibrio vs. 1/T) y se calcularon la variación de entalpía y entropía de desorción. Con el objetivo de verificar la influencia de los procesos de síntesis sobre las propiedades cinéticas de MFI y MFHI, se efectuaron mediciones de velocidades de absorción y desorción a distintas temperaturas. Para la caracterización de los materiales se aplicaron las técnicas de difracción de rayos – X (DRX), microscopía electrónica de barrido (MEB) y calorimetría diferencial de barrido (CDB).
Supplementary document for Influence of anatomical features of different brain regions on the spatial localization of fiber photometry signals - 5425780.pdf
Creators: name: Montinaro, Cinzia
name: Pisanello, Marco
name: Bianco, Marco
name: Spagnolo, Barbara
name: Pisano, Filippo
name: Balena, Antonio
name: De Nuccio, Francesco
name: Lofrumento, Dario Domenico
name: Verri, Tiziano
name: De Vittorio, Massimo
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplemental Document
Hydrogen Storage in nanostructure materials based on Mg catalyzed by LiBH4.
Creators: name: Puszkiel, J.
Publisher: name: Zenodo
Year: 2009
Subjects: hidruros complejos
almacenamiento de hidrógeno
LiBH4
molienda mecánica
Borohidruros
Fe
Ni

description: Los hidruros complejos son materiales con potenciales propiedades para su utilización como medios sólidos para el almacenamiento de hidrógeno. En el presente trabajo se investigan sistemas hidruros compuestos por Mg–Ni y Mg–Fe combinados con pequeñas cantidades de LiBH4, sintetizados mediante cortos tiempos de molienda mecánica en atmósfera de argón. Los resultados experimentales muestran que en sólo 300 segundos los sistemas hidruros formados alcanzan altas capacidades reversibles de absorción de
 hidrógeno del 7,0 wt% H (LiBH4–Mg–Ni) y 5,5 wt% H (LiBH4–Mg–Fe). Si bien la adición de LiBH4 no modifica las propiedades termodinámicas de los hidruros en base Mg–Ni(–Fe), este introduce cambios microestructurales y morfológicos que resultan en mayores áreas superficiales, partículas con fisuras y microporos, facilitando la difusión del hidrógeno a través del material hidrurado. Al someter el compuesto LiBH4–Mg–Ni a sucesivos ciclos de absorción/desorción de hidrógeno a 350 ºC se detecta la presencia de
 una fase inerte irreversible MgNi3B2, la cual evidencia la interacción Mg–B y podría tener influencia en el comportamiento cinético observado. Por lo tanto, el agregado de LiBH4 cumple un rol catalítico en la mejora de las propiedades almacenamiento de hidrógeno de los materiales bajo estudio.
Paladilhiopsis cattaroensis Grego and Gloe
Creators: name: Grego, Jozef
name: Glöer, Peter
name: Falniowski, Andrzej
name: Hofman, Sebastian
name: Osikowski, Artur
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Littorinimorpha
Moitessieriidae
Paladilhiopsis
Paladilhiopsis cattaroensis

description: Paladilhiopsis cattaroensis Grego and Glöe r, n. sp.
(Figs 3-4)
 Type locality
Montenegro: Herceg Novi, Zelenika - Kuti, side rivulet of Opaĉica, spring from well behind last house, 42.462747°N, 18.587347°E, (Fig. 2E).
 Type material
Holotype, Type locality, J. Grego and Z. P. Erőss leg., 25.07.201 6 (HNHM 103039).
 Measurements
Holotype: H 2.0 mm; W 0.83 mm; BH 1.13 mm; BW 0.73 mm; AH 0.63 mm; AW 0.49 mm.
 Etymology
Named after its type locality situated in the northern part of Kotor (Cattaro) Bay.
 Description
Two mm high fragile shell, yellowish corneous, translucent with five convex whorls separated by deep suture. The surface smooth and shiny. Shell elongate, oval-conical, slightly tapering towards semi-blunt apex. Umbilicus closed. Aperture asymmetric, tear shaped, attached to the body whorl at its upper columellar side. Peristome margin blunt, equally thick and not reflected. Outer lip not protruding beyond body whorl and frontal shell profile. Lateral profile of outer lip straight.
 Differentiating features
 The new species is distinguished from Paladilhiopsis gittenbergeri (Reischütz and Reischütz, 2008) (Vau i Dejës, Albania) by its smaller more slender shell shape with a blunter apex and proportionally much smaller aperture. Paladilhiopsis falniowskii (Grego et al., 2017) (Krumë, Albania) has a larger shell with proportionally larger body whorl and a larger, differently positioned aperture. It differs from syntopic Stygobium hercegnoviensis n. sp. by its larger, more inflated, more conical shell with a proportionally smaller apex, proportionally larger and more elongated aperture, and more tumid whorls.
 Habitat
The type locality is an outlet from the stony well build some centuries ago to supply the water to adjacent gardens and houses.
 Distribution
 Known only from the type locality, where it was found together with the Stygobium hercegnoviensis n. sp. The species likely inhabits the adjacent stygobiont habitats around Zelenika basin.
 Remarks
 The assignment of the new species to the genus Paladilhiopsis is only provisional, until the molecular data become available.
description: Published as part of Grego, Jozef, Glöer, Peter, Falniowski, Andrzej, Hofman, Sebastian & Osikowski, Artur, 2019, New subterranean freshwater gastropod species from Montenegro (Mollusca, Gastropoda, Moitessieriidae, and Hydrobiidae), pp. 71-90 in Ecologica Montenegrina 20 (2019) on pages 76-77, DOI: 10.37828/em.2019.20.6, http://zenodo.org/record/13359679
Targeting the Highly Conserved Sequences in Influenza A Virus
Creators: name: Hashem, Anwar
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Influenza
Hemagglutinin
Vaccine
CD40L
Conserved sequences
Universal antibodies
Universal vaccine
Nucleoprotein
Recombinant adenovirus
Fusion peptide
Broadly neutralizing antibodies

description: All challenges associated with influenza A viruses including antigenic variation in hemagglutinin (HA) and neuraminidase (NA), the evolving drug resistance and the drawbacks of current vaccines hinder our ability to control this constant threat. Furthermore, gene reassortment as well as the direct transmission of highly pathogenic avian viruses to humans can result in an occasional emergence of novel influenza strains with devastating pandemic potential. Therefore, it is crucial to investigate alternative approaches to better control these viruses and to develop new prophylactic and treatment options. Targeting highly conserved epitopes or antigens among the different subtypes of influenza A virus could offer protection against broad range of influenza viruses, including emerging strains. In my research, I have investigated the potential of broadly neutralizing antibodies against HA and conducted mechanistic study of a prototype vaccine based on the highly conserved nucleoprotein (NP). We recently found that the 14 amino acids of the amino-terminus of the fusion peptide of influenza HA2 subunit is the only universally conserved sequence in all HA subtypes of influenza A and the two lineages of influenza B viruses. Here, I show that universal antibodies targeting this linear sequence in the viral HA (Uni-1 antibodies) can cross-neutralize multiple subtypes of influenza A virus by inhibiting the pH-dependant fusion of viral and cellular membranes. It is noted that the influenza NP is a highly conserved antigen and has the potential to induce heterosubtypic immunity against divergent subtypes of influenza A virus. However, NP-based vaccination only affords weak protective immunity compared to HA. This is mostly due to the non-sterilizing immunity induced by NP. Using CD40 ligand (CD40L), a key regulator of the immune system, as both a targeting ligand and a molecular adjuvant, I show that single immunization with recombinant adenovirus carrying a fused gene encoding the secreted NP-CD40L fusion protein provided robust and long-lasting protection against influenza in normal mice. It enhanced both B-cell and T-cell responses and augmented the role of both NP-specific antibodies and CTLs in protection. Importantly, it afforded effective protection in CD40L and CD4 deficient mice, confirming that the induced protection is CD40L-mediated and CD4+ T cell-independent. The rapid evolution of the influenza A viruses necessitates the development of new alternatives to contain this medically important pathogen. The results of these studies could significantly contribute to future vaccine development and avert the necessity of yearly vaccine updates.
Regulation of Neural Precursor Cell Fate by the E2f3a and E2f3b Transcription Factors
Creators: name: Julian, Lisa
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Neural stem cell
E2f
Transcription
Sox2
Neurogenesis
Gene regulation
Brain development

description: The classical cell cycle regulatory pathway is well appreciated as a key regulator of cell fate determination during neurogenesis; however, the extent of pRB/E2F function in neural stem and progenitor cells is not fully understood, and insight into the mechanisms underlying its connection with cell fate regulation are lacking. The E2F3 transcription factor has emerged as an important regulator of neural precursor cell (NPC) proliferation in the embryonic and adult forebrain, and we demonstrate here that it also influences the self-renewal potential of NPCs. Using knockout mouse models of individual E2F3 isoforms, we demonstrate the surprising result that the classical transcriptional activator E2F3a represses NPC self-renewal and promotes neuronal differentiation, while E2F3b promotes the expansion of the NPC pool and inhibits differentiation. We attribute these opposing activities to a unique mechanism of transcriptional regulation at the Sox2 locus, a key regulator of stem cell pluripotency, whereby E2F3a recruits transcriptional repressors to this site, and E2F3b promotes Sox2 activation. Importantly, E2F3a-mediated Sox2 regulation is necessary for cognitive function in the adult. Additionally, through the determination of genome-wide promoter binding sites for E2f3 isoforms as well as E2F4, another key regulator of NPC self-renewal, we determined that E2Fs are poised to regulate an extensive set of target genes with key roles in regulating diverse cell fate choices in NPCs, including self-renewal, cell death, progenitor expansion, maintenance of the precursor state, and differentiation. Together, these results reveal a diversity of function for E2Fs in the control of neural precursor cell fate, and identify E2F3 isoforms as important regulators of the pluripotency and stem cell maintenance gene Sox2.
Defining a public model for participatory media practice: a case study of the ABC website Pool
Creators: name: Ardley, Suzi
Publisher: name: Swinburne
Year: 2024

description: This paper reviews the way that participatory media practices have been adopted by cultural institutions such as the Australian Broadcasting Corporation (ABC). A critique of the ABC's adoption of participatory media in relation to its strategy, positioning and charter is used to suggest that a clear framework for a distinctly public form of participatory media is required. By looking at the ABC's experimental social media site Pool, as an example of both the possibilities and challenges for the ABC, it is possible to start to define such a distinctly public form of participatory media.