cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Local Hydrodynamics in a DN300 Pump-Mixer
Creators: name: Wirz, Dominic
Publisher: name: Zenodo
Year: 2022
Subjects: Pump-Mixer, Droplet size distribution, Pumping-curve, Neural Network, Image-based, Probe, Shadowgraphic, Measurement, Multiphase

description: These are the slides of a presentation on the International Solvent Extraction Conference in 2022 in Goetheborg, Sweden.
Microscopic theory for the pair correlation function of liquidlike colloidal suspensions under shear flow
Creators: name: Banetta, Luca
name: Leone, Francesco
name: Anzivino, Carmine
name: Murillo, Michael S.
name: Zaccone, Alessio
Publisher: name: arXiv
Year: 2022
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Chemical Physics (physics.chem-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We present a theoretical framework to investigate the microscopic structure of concentrated hard-sphere colloidal suspensions under strong shear flows by fully taking into account the boundary-layer structure of convective diffusion. We solve the pair Smoluchowski equation with shear separately in the compressing and extensional sectors of the solid angle, by means of matched asymptotics. A proper, albeit approximate, treatment of the hydrodynamic interactions in the different sectors allows us to construct a potential of mean force containing the effect of the flow field on pair correlations. We insert the obtained pair potential in the Percus-Yevick relation and use the latter as a closure to solve the Ornstein-Zernike integral equation. For a wide range of either the packing fraction $η$ and the Péclet ($\textrm{Pe}$) number, we compute the pair correlation function and extract scaling laws for its value at contact. For all the considered value of $\textrm{Pe},$ we observe a very good agreement between theoretical findings and numerical results from literature, up to rather large values of $η.$ The theory predicts a consistent enhancement of the structure factor $ S(k)$ at $k \to 0,$ upon increasing the $\textrm{Pe}$ number. We argue this behaviour may signal the onset of a phase transition from the isotropic phase to a non-uniform one, induced by the external shear flow.
ВЕНЧУРНАЯ ЭКОСИСТЕМА ЕВРОПЕЙСКОГО СОЮЗА: СОВРЕМЕННОЕ СОСТОЯНИЕ И ОСНОВНЫЕ ТЕНДЕНЦИИ РАЗВИТИЯ
Creators: name: Ю. Ю. Павлова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: венчурный бизнес
венчурная экосистема
венчурный капитал
стартап
экономика инноваций
Европейский союз
бизнес-инкубатор
бизнес-акселератор
Европейский инвестиционный банк
МСП.

description: В статье рассматривается функционирование венчурной индустрии Европейского союза. Рассмотрены механизмы государственной поддержки инновационного предпринимательства, дана оценка эффективности политики ЕС по стимулированию венчурного сектора. Проведен SWOT-анализ венчурной экосистемы ЕС, дана оценка влияния наднациональных органов на развитие институтов венчурного бизнеса.
ХАРАКТЕРИСТИКА КРЕДИТНОЙ ПОЛИТИКИ И УПРАВЛЕНИЕ КРЕДИТНЫМ ПОРТФЕЛЕМ КОММЕРЧЕСКИХ БАНКОВ В СОВРЕМЕННЫХ РЫНОЧНЫХ УСЛОВИЯХ
Creators: name: Р. С. Парахин
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: кредитный портфель
коммерческий банк
управление кредитным портфелем
диверсификация
критерии оценки качества коммерческого банка
сомнительные кредиты
нормы обязательного резервирования

description: В данной статье было рассмотрено современное состояние и проблемы кредитной политики коммерческого банка. Рассмотрена специфика их деятельности с позиций современного развития финансового сектора страны. В статье было проведено сопоставление динамики изменения объема кредитного портфеля и чистой прибыли ведущих банков России и представлены пути совершенствования управления кредитным портфелем коммерческим банком на основании внешних и внутренних факторов влияния
HELIOS-K: An Ultrafast, Open-source Opacity Calculator for Radiative Transfer
Creators: name: Grimm, Simon L.
name: Heng, Kevin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: We present an ultrafast opacity calculator that we name HELIOS-K. It takes a line list as an input, computes the shape of each spectral line and provides an option for grouping an enormous number of lines into a manageable number of bins. We implement a combination of Algorithm 916 and Gauss-Hermite quadrature to compute the Voigt profile, write the code in CUDA and optimise the computation for graphics processing units (GPUs). We restate the theory of the k-distribution method and use it to reduce $\sim 10^5$ to $10^8$ lines to $\sim 10$ to $10^4$ wavenumber bins, which may then be used for radiative transfer, atmospheric retrieval and general circulation models. The choice of line-wing cutoff for the Voigt profile is a significant source of error and affects the value of the computed flux by $\sim 10\%$. This is an outstanding physical (rather than computational) problem, due to our incomplete knowledge of pressure broadening of spectral lines in the far line wings. We emphasize that this problem remains regardless of whether one performs line-by-line calculations or uses the k-distribution method and affects all calculations of exoplanetary atmospheres requiring the use of wavelength-dependent opacities. We elucidate the correlated-k approximation and demonstrate that it applies equally to inhomogeneous atmospheres with a single atomic/molecular species or homogeneous atmospheres with multiple species. Using a NVIDIA K20 GPU, HELIOS-K is capable of computing an opacity function with $\sim 10^5$ spectral lines in $\sim 1$ second and is publicly available as part of the Exoclimes Simulation Platform (ESP; www.exoclime.org).
description: Accepted by ApJ. 8 pages, 5 figures
A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007
Creators: name: Kimmick, G.
name: Merino, M.J.
name: Nabell, L.
name: Rugo, H
name: Miller, K.D.
name: Carey, L.
name: Jones, D.R.
name: Steeg, P.S.
name: Althouse, S.K.
Publisher: name: Springer New York LLC
Year: 2014

description: Preclinical data suggest that medroxyprogesterone acetate (MPA) has both anti-metastatic and anti-angiogenic activity in the absence of hormone receptors (HR). This phase II trial assessed the activity of MPA alone or in combination with low-dose chemotherapy in patients with metastatic HR-negative breast cancer. Postmenopausal women with HR-negative disease were eligible if they had not received more than 3 chemotherapy regimens for metastatic disease. All patients were treated with MPA 1,000–1,500 mg/day orally; patients in cohort two also received low-dose oral cyclophosphamide and methotrexate (ldCM, 50 mg/day and 2.5 mg twice daily on Days 1 and 2 each week). Tissue and circulating biomarkers were assessed serially. The primary endpoint was clinical benefit response defined as objective response or stable disease >6 months. Thirty patients were enrolled (14 MPA monotherapy; 16 MPA + ldCM); median age was 55 (35–80); nearly all had visceral involvement. Despite dose escalation in 90 % of patients, only 17 (57 %) patients ever achieved MPA trough concentrations >50 ng/ml. One patient developed grade 4 renal failure in the setting of rapid disease progression and dehydration. There were no objective responses. One patient in each cohort (~7 %) had stable disease for > 6 months. Skin Nm23 expression increased after 4 weeks of MPA + ldCM, but there were no significant changes in TSP-1, PAI-1 antigen, or PAI-1 activity. MPA had limited activity and does not warrant further development in patients with HR-negative advanced breast cancer. Poor bioavailability limited exposure despite dose escalation.
Machine Learning for Metasurfaces Design and Their Applications
Creators: name: Mishra, Kumar Vijay
name: Elbir, Ahmet M.
name: Zaghloul, Amir I.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Applied Physics (physics.app-ph)
subject: Signal Processing (eess.SP)
subject: Machine Learning (stat.ML)
subject: FOS: Physical sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Metasurfaces (MTSs) are increasingly emerging as enabling technologies to meet the demands for multi-functional, small form-factor, efficient, reconfigurable, tunable, and low-cost radio-frequency (RF) components because of their ability to manipulate waves in a sub-wavelength thickness through modified boundary conditions. They enable the design of reconfigurable intelligent surfaces (RISs) for adaptable wireless channels and smart radio environments, wherein the inherently stochastic nature of the wireless environment is transformed into a programmable propagation channel. In particular, space-limited RF applications, such as communications and radar, that have strict radiation requirements are currently being investigated for potential RIS deployment. The RIS comprises sub-wavelength units or meta-atoms, which are independently controlled and whose geometry and material determine the spectral response of the RIS. Conventionally, designing RIS to yield the desired EM response requires trial and error by iteratively investigating a large possibility of various geometries and materials through thousands of full-wave EM simulations. In this context, machine/deep learning (ML/DL) techniques are proving critical in reducing the computational cost and time of RIS inverse design. Instead of explicitly solving Maxwell's equations, DL models learn physics-based relationships through supervised training data. The ML/DL techniques also aid in RIS deployment for numerous wireless applications, which requires dealing with multiple channel links between the base station (BS) and the users. As a result, the BS and RIS beamformers require a joint design, wherein the RIS elements must be rapidly reconfigured. This chapter provides a synopsis of DL techniques for both inverse RIS design and RIS-assisted wireless systems.
description: Book chapter, 70 pages, 12 figures, 2 tables. arXiv admin note: substantial text overlap with arXiv:2101.09131, arXiv:2009.02540
УПРАВЛЕНИЕ СТРАТЕГИЧЕСКИМ РАЗВИТИЕМ РОССИЙСКИХ ПРЕДПРИЯТИЙ: ПРОБЛЕМЫ И РЕШЕНИЯ
Creators: name: Н. Н. Петренко
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: стратегическое управление
управление развитием компании
прибыль
менеджер
руководитель
разработка стратегии
инновации

description: В статье рассматриваются проблемы и решения стратегического управления на предприятии. Изучается работа менеджеров российских предприятий, их шаблонность и нововведения. Уделяется внимание работе руководителей с инновационными проектам, которые составляют немалую долю в стратегии развития предприятия. Рассматриваются основные характеристики и способности, которыми должен обладать менеджер, что в свою очередь позволяет акционерам и сотрудникам предприятия оценить работу руководителя. Принимая во внимание стратегию развития международных компаний, описываются принятия решений руководителем с учетом особенностей российской экономики.
A study of the factors influencing air removal in Out-of-Autoclave processing of composites
Creators: name: Torres, J.J.
name: Sket, F.
name: Gonzalez, C.
name: Simmons, M.
Publisher: name: Zenodo
Year: 2021
Subjects: compuestos polimericos
fuera de autoclave
tomografia de rayos X
tomografia sincrotron
fabricacion

description: Hoy en día, la fabricación de piezas de material compuesto mediante procesos que no requieren autoclave está ganando importancia, debido a la reducción de grandes inversiones iniciales y costes recurrentes. Entre estas tecnologías, se encuentra la consolidación de preimpregnados diseñados para fuera de autoclave (OoA) mediante bolsa de vacío (VBO) y un horno industrial, lo que permite la fabricación de piezas estructurales de alta calidad sin la necesidad de autoclaves. Estos preimpregnados no están completamente impregnados, creando unos canales dentro de los mazos de fibras, los cuales permiten evacuar el aire del interior o los volátiles generados durante el ciclo de curado. El objetivo de este trabajo se enfoca en entender y explicar la distribución espacial, los mecanismos de formación y de transporte de poros durante la consolidación de preimpregnados OoA mediante el método de VBO. Este trabajo incluye estudios paralelos llevados a cabo mediante tomografía de rayos X (XCT) en 3D, para determinar los factores más relevantes en el proceso de extracción de aire en laminados de material compuesto producidos manualmente (HLU) y mediante un sistema de posicionamiento automático de fibras (AFP). Se efectuó un gran desafío, que consistió en monitorear de manera precisa la evolución de la porosidad durante el curado del material, algo que no se ha hecho hasta ahora y mucho menos mediante una técnica visual en 3D. Esta combinación de monitoreo de la dinámica de la evolución de los poros mediante XCT en laboratorio y tomografía sincrotrón (SXCT) a diferentes resoluciones durante el proceso de curado, proporcionó una comprensión profunda del proceso de evacuación de poros, creando una estrategia para el posterior desarrollo de materiales OoA.
СОВЕРШЕНСТВОВАНИЕ СТРАТЕГИЧЕСКОГО УПРАВЛЕНИЯ ПЕРСОНАЛОМ ПРЕДПРИЯТИЯ
Creators: name: Р. Н. Петренко
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: управление пресоналом
трудовые ресурсы
бюрократическая структура
органическая структура
квалификация
бестарифная система.

description: В статье рассматривается совершенствование стратегического управления персоналом предприятия. Уделяется внимание бюрократической и органической структуре. Детально изучается бестарифная ситема оплаты труда, как один из вариантов управления персоналом предприятия. Рассматривается ряд факторов из которых складывается бестарифная система. Описывается область применения рассматриваемой системы. Изучается возможность повышения эффективности работы на предприятии, учитывая совершенствование и уникальность поцессов управления персоналом. Рассматриваются методы и решения эффективного управления персоналом.
РАЗВИТИЕ ИНСТИТУТА ПАРТНЕРСТВА ГОСУДАРСТВА И БИЗНЕСА В РОССИИ НА СОВРЕМЕННОМ ЭТАПЕ
Creators: name: И. Г. Пивень
name: П. А. Никонова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: институт государственно-частного партнерства
национальная стратегия
развитие регионов
национальные проекты

description: В статье рассмотрены институциональные особенности развития партнерства государства и бизнеса в последние годы в России. Выделены приоритеты в развитии для обеспечения устойчивости страны и регионов, в частности развитие государственно-частного партнерства (ГЧП). Рассмотрены изменения законодательной базы, определяющей отбор участников ГЧП, документирование и порядок взаимодействия и контроля реализации проектов ГЧП, кроме этого рассмотрено формирование и развитие Национального центра ГЧП и Института ГЧП. Рассмотрены итоги ГЧП за последние 10 лет по данным Минэкономразвития России
Emerging Prototyping Activities in Joint Radar-Communications
Creators: name: R., Bhavani Shankar M.
name: Mishra, Kumar Vijay
name: Alaee-Kerahroodi, Mohammad
Publisher: name: arXiv
Year: 2022
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The previous chapters have discussed the canvas of joint radar-communications (JRC), highlighting the key approaches of radar-centric, communications-centric and dual-function radar-communications systems. Several signal processing and related aspects enabling these approaches including waveform design, resource allocation, privacy and security, and intelligent surfaces have been elaborated in detail. These topics offer comprehensive theoretical guarantees and algorithms. However, they are largely based on theoretical models. A hardware validation of these techniques would lend credence to the results while enabling their embrace by industry. To this end, this chapter presents some of the prototyping initiatives that address some salient aspects of JRC. We describe some existing prototypes to highlight the challenges in design and performance of JRC. We conclude by presenting some avenues that require prototyping support in the future.
description: Book chapter, 54 pages, 13 figures, 10 tables
Tips and tricks in triple-negative breast cancer: How to manage patients in real-life practice?
Creators: name: Carey, L.
name: Viale, G.
name: Ellis, P.
name: Abramowicz, M.
name: Piccart, M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: This article has been developed following, and drawing on the content of, a satellite meeting at the fifth International Breast Cancer Conference, held in Paris, France, on 29 January 2011. The purpose of the meeting was to examine several questions relating to triple-negative breast cancer (TNBC): How should TNBC be defined? Are there clinically important TNBC subtypes? Should patients be given adjuvant or neoadjuvant treatment for TNBC ?Should patients with TNBC and their families have genetic tests? How should relapsing or metastatic TNBC be treated? Using a real-life case study, at each stage of the patient care pathway from diagnosis through assessment to treatment, the audience was encouraged to vote on potential decisions, before an expert panel on which we all sat discussed the evidence and presented what we consider constitutes best clinical practice. In this article we share the proceedings of the meeting, which we believe contained valuable educational content of potential interest to the wider healthcare community.
Giant Triplet Proximity Effect in $π$-biased Josephson Junctions with Spin-Orbit Coupling
Creators: name: Jacobsen, Sol
name: Linder, Jacob
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In diffusive Josephson junctions the phase-difference $ϕ$ between the superconductors strongly influences the spectroscopic features of the layer separating them. The observation of a uniform minigap and its phase modulation were only recently experimentally reported, demonstrating agreement with theoretical predictions up to now - a vanishing minigap at $ϕ=π$. Remarkably, we find that in the presence of intrinsic spin-orbit coupling a giant proximity effect due to spin-triplet Cooper pairs can develop at $ϕ=π$, in complete contrast to the suppressed proximity effect without spin-orbit coupling. We here report a combined numerical and analytical study of this effect, proving its presence solely based on symmetry arguments, which makes it independent of the specific parameters used in experiments. We show that the spectroscopic signature of the triplets is present throughout the entire ferromagnetic layer. Our finding offers a new way to artificially create, control and isolate spin-triplet superconductivity.
description: 6 pages, 6 figures. Accepted for publication in Phys. Rev. B
ФИЗИЧЕСКИЕ ЛИЦА – НАЛОГОВЫЕ РЕЗИДЕНТЫ, КАК КОНТРОЛИРУЮЩИЕ ЛИЦА ИНОСТРАННЫХ КОМПАНИЙ
Creators: name: О. И. Попкова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: налоговый резидент
налогообложение физических лиц
контролируемые иностранные компании
автоматических обмен
налоговая информация
бенефициарный собственник.

description: Статья посвящена актуальной теме в области налогообложения – налоговому резидентству физических лиц и специальным правилам, имплементированным в национальное налоговое законодательство Российской Федерации – контролируемые иностранные компании. Правила определения статуса налогового резидентства являются одними из ключевых вопросов в сфере налогообложения физических лиц в Российской Федерации. Усложнение налогового законодательства в связи с введением в него новых норм о контролируемых иностранные компаниях (далее – КИК), воспринимается как увеличение степени правовой неопределенности, а, следовательно, появление новых налоговых рисков. С целью снижения налоговой нагрузки резиденты Российской Федерации используют схемы международного налогового планирования, не подпадающие под действие национального налогового законодательства РФ, путем распределения активов в разных налоговых юрисдикциях. После введенных норм (гл. 3.4 НК РФ) в 2015 году претерпели радикальные изменения схемы ведения международной коммерции. На сегодняшний день использование офшорных компаний в структурах является высокорискованным, наказуемым и в большинстве случаев экономически невыгодным с налоговой точки зрения. Нельзя не отметить, что для эффективного контроля со стороны налоговых органов необходим обмен налоговой информацией со многими иностранными юрисдикциями (в том числе офшорными зонами), производимый в автоматическом режиме
ФИНАНСОВОЕ ОБЕСПЕЧЕНИЕ СОЦИАЛЬНО-ЭКОНОМИЧЕСКОЙ СФЕРЫ РЕГИОНА (НА ПРИМЕРЕ АЛТАЙСКОГО КРАЯ)
Creators: name: В. И. Прусова
name: А. А. Елисова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: бюджетное регулирование
виды бюджетов
социальная сфера
социальная политика
финансовое обеспечение

description: В данной статье рассматривается роль бюджета, как форма образования и расходования фонда денежных средств, как государства в целом, так и на уровне регионов и органов местного самоуправления. Основной акцент статьи показать финансовое обеспечение социально-экономической сферы региона, на примере Алтайского края. Особое внимание уделено анализу доходов и расходов бюджета Алтайского края. Авторами более детально рассмотрена динамика расходов на социальную политику.
High-fidelity one-dimensional model of solid propellant combustion: formulation, numerical strategy, coupling with a CFD software for simulating ignition transients in complete solid rocket motors
Creators: name:  L. FRANCOIS
name:   J. DUPAYS
name:   M. MASSOT
Publisher: name: Proceedings of  the 9th European Conference for Aerospace Sciences. Lille, France, 27 June - 1 July, 2022
Year: 2022
Subjects: PROPULSION PHYSICS
SOLID ROCKET MOTOR

description: Solid propellant combustion is a key element in rocket propulsion and has been extensively studied since the 1950s. This particular problem involves a solid phase and a gas phase, separated by an interface (surface of the solid). At its surface, the solid propellant is decomposed through a pyrolysis and gasification process, causing the surface to regress. The gaseous products react and form a flame which heats back the solid, allowing for a sustained combustion. It is essential to understand the underlying physics to allow for clever combustion chamber designs. A key element is the regression speed of the propellant surface, and its dependence on the combustion chamber conditions. Modelling and simulating the solid propellant combustion are thus key elements for the CFD simulations of complete solid rocket motors. Due to the small thickness of the propellant flame (~100 microns), it is intractable to use a sufficiently well resolved mesh to compute this flame in a conventional CFD solver for a full scale motor. An alternative solution is to rely on a one-dimensional model to compute the phenomena occurring near the surface of the propellant. We first describe the development of this submodel and of the related numerical tools. We begin by analysing a steady-state semi-analytical model, allowing for a clear understanding of the major parameters and the concept of eigenvalue. We derive an unsteady model with an unsteady gas phase. Semi-discretising in space via finite-volumes the corresponding PDE yields a set of differential-algebraic equations. This requires special care when choosing the time integration method, leading to the implementation of specific high-order methods with time step adaptation. The numerical strategy is then compared to other more conventional methods on various one-dimensional test cases, such as limit cycles and detailed kinetics. It is more reliable and precise, while improving computational efficiency. The coupling methodology with the multiphysics CFD solver CEDRE from ONERA is detailed, and a comparison is made with previous models from ONERA on coupled simulations of the ignition in academic configurations. The model is shown to be robust and computationally efficient. The importance of the coupling strategy and its effect on the overall motor behaviour is also emphasized. A great advantage of the presented approach is the discretised unsteady gas phase in the boundary condition model, which enables the use of detailed models, e.g. realistic flame structure, nonlinear behaviour... This was previously not possible when using other simpler boundary models from the literature.
PARP and cancer - If it's broke, don't fix it
Creators: name: Sharpless, N.E.
name: Carey, L.A.
Publisher: name: Massachussetts Medical Society
Year: 2011

description: With apologies to Nietzsche, who once said “that which does not kill us makes us stronger,” sometimes that which does not kill weakens us so the next blow will be lethal. In this issue of the Journal, O'Shaughnessy and colleagues1 describe a study in which poly(adenosine diphosphate-ribose) polymerase (PARP) inhibition was added to cytotoxic chemotherapy in an effort to set breast cancers up for that “next blow” (ClinicalTrials.gov number, NCT00540358). PARP inhibitors represent an exciting new therapeutic direction in oncology: the rational targeting of tumor-cell vulnerability during DNA repair.
A study of global magnetic helicity in self-consistent spherical dynamos
Creators: name: Gupta, Parag
name: Simitev, Radostin D.
name: MacTaggart, David
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Fluid Dynamics (physics.flu-dyn)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: Magnetic helicity is a fundamental constraint in both ideal and resistive magnetohydrodynamics. Measurements of magnetic helicity density on the Sun and other stars are used to interpret the internal behaviour of the dynamo generating the global magnetic field. In this note, we study the behaviour of the global relative magnetic helicity in three self-consistent spherical dynamo solutions of increasing complexity. Magnetic helicity describes the global linkage of the poloidal and toroidal magnetic fields (weighted by magnetic flux), and our results indicate that there are preferred states of this linkage. This leads us to propose that global magnetic reversals are, perhaps, a means of preserving this linkage, since, when only one of the poloidal or toroidal fields reverses, the preferred state of linkage is lost. It is shown that magnetic helicity indicates the onset of reversals and that this signature may be observed at the outer surface.
description: To appear in Geophysical and Astrophysical Fluid Dynamics [Accepted 2022-10-14]
Improved Surgical Outcomes for Breast Cancer Patients Receiving Neoadjuvant Aromatase Inhibitor Therapy: Results from a Multicenter Phase II Trial
Creators: name: Fleming, G.F.
name: Commean, P.
name: Giuntoli, T.
name: Esserman, L.J.
name: Bae, K.
name: Leight Jr., G.S.
name: Budd, G.T.
name: Ellis, M.J.
name: Luo, J.
name: Olson Jr., J.A.
name: Carey, L.A.
name: Marcom, P.K.
name: Harris, L.A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Background: Neoadjuvant aromatase inhibitor therapy has been reported to improve surgical outcomes for postmenopausal women with clinical stage II or III hormone receptor-positive breast cancer. A multicenter phase II clinical trial was conducted to investigate the value of this approach for US surgical practice. Study Design: One hundred fifteen postmenopausal women with >2 cm, estrogen receptor (ER) or progesterone receptor (PgR)-positive breast cancer were enrolled in a trial of 16 to 24 weeks of letrozole 2.5 mg daily before operation. Results: One hundred six patients were eligible for primary analysis, 96 underwent operations, 7 received chemotherapy after progressive disease, and 3 did not undergo an operation. Baseline surgical status was marginal for breast-conserving surgery (BCS) in 48 (45%), 47 were definitely ineligible for BCS (44%), and 11 were inoperable by standard mastectomy (10%). Overall Response Evaluation Criteria In Solid Tumors clinical response rate in the breast was 62%, with 12% experiencing progressive disease. Fifty percent underwent BCS, including 30 of 46 (65%) patients who were initially marginal for BCS and 15 of 39 (38%) patients who were initially ineligible for BCS. All 11 inoperable patients successfully underwent operations, including 3 (27%) who had BCS. Nineteen percent of patients undergoing mastectomy had a pathologic T1 tumor, suggesting that some highly responsive tumors were overtreated surgically. Conclusions: Neoadjuvant aromatase inhibitor improves operability and facilitates BCS, but there was considerable variability in responsiveness. Better techniques to predict response, determine residual tumor burden before operation, and greater willingness to attempt BCS in responsive patients could additionally improve the rate of successful BCS.
ПОЗИЦИОНИРОВАНИЕ БРЕНДИНГА И ЕГО РОЛЬ В ФОРМИРОВАНИИ ИМИДЖА ФИРМЫ
Creators: name: Я. Р. Рамазанова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: брендинг
позиционирование
имидж
конкурентоспособность
рынок
бренд-менеджмент
репутация
концепция позиционирования

description: В данной статье проанализирована роль брендинга и его влияние на имидж фирмы. Основное внимание уделено важности процесса позиционирования бренда для создания положительной репутации фирмы. Приведено определение понятию позиционирование бреда. Приведены основные принципы брендинга. Представлены основные задачи позиционирования бренда. Выявлены основные факторы, отрицательно влияющие на имидже фирмы. Разработан алгоритм позиционирования. В статье проанализированы ситуации, сказывающиеся на имидже фирмы
Competition between Hund's coupling and Kondo effect in a one-dimensional extended periodic Anderson model
Creators: name: Hagymasi, I.
name: Solyom, J.
name: Legeza, O.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the ground-state properties of an extended periodic Anderson model to understand the role of Hund's coupling between localized and itinerant electrons using the density-matrix renormalization group algorithm. By calculating the von Neumann entropies we show that two phase transitions occur and two new phases appear as the hybridization is increased in the symmetric half-filled case due to the competition between Kondo-effect and Hund's coupling. In the intermediate phase, which is bounded by two critical points, we found a dimerized ground state, while in the other spatially homogeneous phases the ground state is Haldane-like and Kondo-singlet-like, respectively. We also determine the entanglement spectrum and the entanglement diagram of the system by calculating the mutual information thereby clarifying the structure of each phase.
description: 9 pages, 9 figures, revised version, accepted for publication in PRB
Performance Portability Study of Linear Algebra Kernels in OpenCL
Creators: name: Rupp, Karl
name: Tillet, Philippe
name: Rudolf, Florian
name: Weinbub, Josef
name: Grasser, Tibor
name: Jüngel, Ansgar
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Software (cs.MS)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Performance (cs.PF)
subject: FOS: Computer and information sciences

description: The performance portability of OpenCL kernel implementations for common memory bandwidth limited linear algebra operations across different hardware generations of the same vendor as well as across vendors is studied. Certain combinations of kernel implementations and work sizes are found to exhibit good performance across compute kernels, hardware generations, and, to a lesser degree, vendors. As a consequence, it is demonstrated that the optimization of a single kernel is often sufficient to obtain good performance for a large class of more complicated operations.
description: 11 pages, 8 figures, 2 tables, International Workshop on OpenCL 2014
Phenotypic Equilibrium as Probabilistic Convergence in Multi-phenotype Cell Population Dynamics
Creators: name: Jiang, Da-Quan
name: Wang, Yue
name: Zhou, Da
Publisher: name: arXiv
Year: 2014
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: FOS: Biological sciences
subject: 60J85 (Primary), 92D25, 34D05 (Secondary)

description: We consider the cell population dynamics with $n$ different phenotypes. Both the Markovian branching process model (stochastic model) and the ordinary differential equation (ODE) system model (deterministic model) are presented, and exploited to investigate the dynamics of the phenotypic proportions. We will prove that in both models, these proportions will tend to constants regardless of initial population states ("phenotypic equilibrium") under weak conditions, which explains the experimental phenomenon in Gupta et al.'s paper. We also prove that Gupta et al.'s explanation is the ODE model under a special assumption. As an application, we will give sufficient and necessary conditions under which the proportion of one phenotype tends to $0$ (die out) or $1$ (dominate). We also extend our results to non-Markovian cases.
Understanding and treating triple-negative breast cancer
Creators: name: Carey, L.A.
name: Anders, C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Triple-negative breast cancer is a subtype of breast cancer that is clinically negative for expression of estrogen and progesterone receptors (ER/PR) and HER2 protein. It is characterized by its unique molecular profile, aggressive behavior, distinct patterns of metastasis, and lack of targeted therapies. Although not synonymous, the majority of triple-negative breast cancers carry the "basal-like" molecular profile on gene expression arrays. The majority of BRCA1-associated breast cancers are triple-negative and basal-like; the extent to which the BRCA1 pathway contributes to the behavior of sporadic basal-like breast cancers is an area of active research. Epidemiologic studies illustrate a high prevalence of triple-negative breast cancers among younger women and those of African descent. Increasing evidence suggests that the risk factor profile differs between this subtype and the more common luminal subtypes. Although sensitive to chemotherapy, early relapse is common and a predilection for visceral metastasis, including brain metastasis, is seen. Targeted agents, including epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF), and poly (ADP-ribose) polymerase (PARP) inhibitors, are currently in clinical trials and hold promise in the treatment of this aggressive disease.
Small symplectic Calabi-Yau surfaces and exotic 4-manifolds via genus-3 pencils
Creators: name: Baykur, R. Inanc
Publisher: name: arXiv
Year: 2015
Subjects: subject: Symplectic Geometry (math.SG)
subject: Differential Geometry (math.DG)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: We explicitly produce symplectic genus-3 Lefschetz pencils (with base points), whose total spaces are homeomorphic but not diffeomorphic to rational surfaces CP^2 # p (-CP^2) for p= 7, 8, 9. We then give a new construction of an infinite family of symplectic Calabi-Yau surfaces with first Betti number b_1=2,3, along with a surface with b_1=4 homeomorphic to the 4-torus. These are presented as the total spaces of symplectic genus-3 Lefschetz pencils we construct via new positive factorizations in the mapping class group of a genus-3 surface. Our techniques in addition allow us to answer in the negative a question of Korkmaz regarding the upper bound on b_1 of a genus-g fibration.
description: 29 pages, 6 figures. Corrected several typos
СОВЕРШЕНСТВОВАНИЕ УПРАВЛЕНИЯ ПРОИЗВОДСТВЕННЫМИ ЗАПАСАМИ НА ПРЕДПРИЯТИИ
Creators: name: С. В. Рачек
name: А. Е. Байкалова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: производственные запасы
учет
себестоимость
номенклатура
склад.

description: В статье представлена основная информация о понятие производственных запасов и их составе. Цель анализа состоит в повышении рентабельности производства за счет рационального использования таких запасов. Рассматриваются слабые стороны системы управления производственными запасами на предприятиях и актуальные методы их учета. Автором выделены основные направления оптимизации и пути совершенствования системы их управления с целью достижения наиболее эффективных результатов деятельности
Acylindrical hyperbolicity of cubical small-cancellation groups
Creators: name: Arzhantseva, Goulnara N.
name: Hagen, Mark F.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20F06, 20F65, 20F67

description: We provide an analogue of Strebel's classification of geodesic triangles in classical $C'(\frac16)$ groups for groups given by Wise's cubical presentations satisfying sufficiently strong metric cubical small cancellation conditions. Using our classification, we prove that, except in specific degenerate cases, such groups are acylindrically hyperbolic.
description: Revised according to referee comments. This version accepted in Algebraic and Geometric Topology
НЕКОТОРЫЕ ПРОБЛЕМЫ ОЦЕНКИ НЕРАСПРЕДЕЛЕННОЙ ПРИБЫЛИ КАК СОСТАВЛЯЮЩЕЙ КАПИТАЛА КОМПАНИИ
Creators: name: И. В. Ромашкина
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: нераспределенная прибыль; учредители; прибыль
подлежащая распределению; нераспределенная прибыль в обращении; заинтересованные пользователи бухгалтерской отчетности

description: В статье рассматриваются: проблемные факты хозяйственной жизни, связанные с порядком учета использования нераспределенной прибыли, в том числе для финансового обеспечения производственного развития организации и иных аналогичных мероприятий; дивиденды (доходы) учредителей, отчисления в резервный фонд и их влияние на капитал организации; аналитический учет к бухгалтерскому счету 84 «Нераспределенная прибыль (непокрытый убыток); назначение субсчетов, открываемых к счету 84; порядок отражения динамики нераспределенной прибыли, а также её движения в бухгалтерском балансе и отчете об изменениях капитала
ИНСТРУМЕНТЫ ОЦЕНКИ КОНКУРЕНТОСПОСОБНОСТИ
Creators: name: Т. И. Рындина
name: Л. Н. Захарова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: конкурентоспособность
оценка конкурентоспособности
комплексный подход
методы оценки конкурентоспособности
конкурентные преимущества

description: В данной статье рассмотрено понятие конкурентоспособности, а также приведены инструменты оценки конкурентоспособности. Непременным условием конкурентоспособности является возможность организации определить изменения в окружающей среде и в компании и найти лучший вариант их использования по сравнению с конкурентами. Для определения конкурентоспособности предприятия на рынке необходим поиск факторов, воздействующих на возможности выигрыша или проигрыша организации в борьбе с конкурентами, а изучение этих факторов способствует выявлению сильных и слабых сторон в самой фирме и в работе конкурентов
ВЛИЯНИЕ НАЦИОНАЛЬНЫХ ПРОЕКТОВ НА ПОВЫШЕНИЕ КАЧЕСТВА ЖИЗНИ ГРАЖДАН РФ
Creators: name: Е. В. Слепцова
name: А. Пруидзе
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: национальный проект
государственная программа
качество жизни
человеческий капитал.

description: В статье проводится анализ влияния национальных проектов, реализуемых в России, на повышение уровня жизни. Обозначены преимущества национальных проектов перед другими инструментами государственной социально-экономической политики. На примере Краснодарского края показаны возможности успешной реализации национальных проектов на региональном уровне
Phase II trial correlating standardized uptake value with pathologic complete response to pertuzumab and trastuzumab in breast cancer
Creators: name: Carey, L.A.
name: Liu, M.C.
name: Huang, C.-Y.
name: Abramson, V.
name: Park, B.H.
name: Winer, E.P.
name: Wahl, R.L.
name: Connolly, R.M.
name: Cimino-Mathews, A.
name: Rimawi, M.
name: Carpenter, A.
name: Wolff, A.C.
name: Valero, V.
name: Solnes, L.
name: Specht, J.
name: Krop, I.E.
name: Gaffney, K.
name: Storniolo, A.M.
name: Leal, J.P.
name: Stearns, V.
name: Vaklavas, C.
name: Miller, R.S.
name: Camp, M.
Publisher: name: American Society of Clinical Oncology
Year: 2019

description: PURPOSE Predictive biomarkers to identify patients with human epidermal growth factor receptor 2 (HER2)–positive breast cancer who may benefit from targeted therapy alone are required. We hypothesized that early measurements of tumor maximum standardized uptake values corrected for lean body mass (SULmax) on [ 18 F] fluorodeoxyglucose positron emission tomography/computed tomography would predict pathologic complete response (pCR) to neoadjuvant pertuzumab and trastuzumab (PT). PATIENTS AND METHODS Patients with stage II/III, estrogen receptor–negative, HER2-positive breast cancer received four cycles of neoadjuvant PT. [ 18 F]Fluorodeoxyglucose positron emission tomography/computed tomography was performed at baseline and 15 days after PT initiation (C1D15). Eighty evaluable patients were required to test the null hypothesis that the area under the curve of percentage of change in SULmax by C1D15 predicting pCR is less than or equal to 0.65, with a one-sided type I error rate of 10%. RESULTS Eighty-eight women were enrolled (83 evaluable), and 85% (75 of 88) completed all four cycles of PT. pCR after PT alone was 34%. Receiver operating characteristic analysis yielded an area under the curve of 0.76 (90% CI, 0.67 to 0.85), which rejected the null hypothesis. Between patients who obtained pCR versus not, a significant difference in median percent reduction in SULmax by C1D15 was observed (63.8% v 33.5%; P, .001), an SULmax reduction greater than or equal to 40% was more prevalent (86% v 46%; P, .001; negative predictive value, 88%; positive predictive value, 49%), and a significant difference in median C1D15 SULmax (1.6 v 3.9; P, .001) and higher proportion of C1D15 SULmax less than or equal to 3 (93% v 38%; P, .001; negative predictive value, 94%; positive predictive value, 55%) were observed. CONCLUSION Early changes in SULmax predict response to four cycles of PT in estrogen receptor–negative, HER2-positive breast cancer. Once optimized, this quantitative imaging strategy may facilitate a more tailored approach to therapy in this setting.
ВЛИЯНИЕ ФАКТОРОВ МАКРОСРЕДЫ НА КОНКУРЕНТОСПОСОБНОСТЬ ПРОДУКЦИИ ФИРМЫ
Creators: name: Ю. А. Строилова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: конкурентоспособность
факторы конкурентоспособности фирмы
классификация
макросреда
анализ факторов

description: В статье проведен теоретический анализ ряда подходов к пониманию сущности факторов внешней среды, их влияния на уровень конкурентоспособности фирмы. На основе обзора подходов различных авторов к классификации факторов конкурентоспособности фирмы, предложена их обобщённая авторская классификация, а также дана краткая характеристика политико-правовых, экономических, социокультурных, технических факторов. В статье также представлены результаты практического анализа влияния факторов макросреды на конкурентоспособности фирмы и ее продукции на примере конкретного предприятия, с использованием методики PEST-анализа
SpECTRE: A Task-based Discontinuous Galerkin Code for Relativistic Astrophysics
Creators: name: Kidder, Lawrence E.
name: Field, Scott E.
name: Foucart, Francois
name: Schnetter, Erik
name: Teukolsky, Saul A.
name: Bohn, Andy
name: Deppe, Nils
name: Diener, Peter
name: Hébert, François
name: Lippuner, Jonas
name: Miller, Jonah
name: Ott, Christian D.
name: Scheel, Mark A.
name: Vincent, Trevor
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We introduce a new relativistic astrophysics code, SpECTRE, that combines a discontinuous Galerkin method with a task-based parallelism model. SpECTRE's goal is to achieve more accurate solutions for challenging relativistic astrophysics problems such as core-collapse supernovae and binary neutron star mergers. The robustness of the discontinuous Galerkin method allows for the use of high-resolution shock capturing methods in regions where (relativistic) shocks are found, while exploiting high-order accuracy in smooth regions. A task-based parallelism model allows efficient use of the largest supercomputers for problems with a heterogeneous workload over disparate spatial and temporal scales. We argue that the locality and algorithmic structure of discontinuous Galerkin methods will exhibit good scalability within a task-based parallelism framework. We demonstrate the code on a wide variety of challenging benchmark problems in (non)-relativistic (magneto)-hydrodynamics. We demonstrate the code's scalability including its strong scaling on the NCSA Blue Waters supercomputer up to the machine's full capacity of 22,380 nodes using 671,400 threads.
description: 41 pages, 13 figures, and 7 tables. Ancillary data contains simulation input files
РЕАЛИЗАЦИЯ ГОСУДАРСТВЕННОГО ИМУЩЕСТВА В КРАСНОДАРСКОМ КРАЕ
Creators: name: С. Н. Сычанина
name: К. В. Власова
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: государственное имущество
уничтожение
переработка
аукцион
прямая продажа

description: В статье раскрываются способы распоряжения государственным имуществом. Рассмотрены два способа реализации имущества: аукцион и прямая продажа. Рассмотрен и изучен более подробно способ реализации аукцион, функции продавца. Проведен анализ работы распоряжения имуществом за период с 2017 по 2019 год. А также рассмотрен порядок проведения аукциона. Подведены итоги и выделен способ распоряжения имуществом – реализация, как самый эффективный
A general existence result for isothermal two-phase flows with phase transition
Creators: name: Hantke, Maren
name: Thein, Ferdinand
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 76T10, 35L65, 35Q31, 82C26

description: Liquid-vapor flows with phase transitions have a wide range of applications. Isothermal two-phase flows described by a single set of isothermal Euler equations, where the mass transfer is modeled by a kinetic relation, have been investigated analytically in (Quarterly of applied Mathematics, vol.\ LXXI 3 (2013), pp.\ 509-540.). This work was restricted to liquid water and its vapor modeled by linear equations of state. The focus of the present work lies on the generalization of the primary results to arbitrary substances, arbitrary equations of state and thus a more general kinetic relation. We prove existence and uniqueness results for Riemann problems. In particular, nucleation and evaporation are discussed.
ВЛИЯНИЕ ИНФОРМАЦИОННЫХ ТЕХНОЛОГИЙ НА ЭКОНОМИЧЕСКУЮ БЕЗОПАСНОСТЬ
Creators: name: Н. В. Тарасова
name: С. Е. Дорошкин
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: экономическая безопасность
информационная безопасность
правовое обеспечение
развитие
угроза

description: Статья посвящена исследованию вопроса обеспечения информационной составляющей экономической безопасности. Автором рассмотрена классификация угроз информационной безопасности, а также определена сущность дефиниции экономической и информационной безопасности. В ходе работы выделены и обоснованы ключевые направления правового обеспечения информационной безопасности страны и субъектов экономики. Автором сделан вывод о влиянии элемента информационная безопасность на уровень экономической безопасности хозяйствующего субъекта, личности и государства.