cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Electron Structure: Shape, Size and GPDs in QED
Creators: name: Miller, Gerald A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The shape of the electron is studied using lowest-order perturbation theory. Quantities used to probe the structure of the proton: form factors, generalized parton distributions, transverse densities, Wigner distributions and the angular momentum content are computed for the electron-photon component of the electron wave function. The influence of longitudinally polarized photons, demanded by the need for infrared regularization via a non-zero photon mass, is included. The appropriate value of the photon mass depends on experimental conditions, and consequently the size of the electron (as defined by the slope of its Dirac form factor) bound in a hydrogen atom is found to be about four times larger than when the electron is free. The shape of the electron, as determined from the transverse density and generalized parton distributions is shown to not be round, and the free electron is shown to be far less round than the bound electron. An electron distribution function (analogous to the quark distribution function) is defined, and that of the bound electron is shown to be suppressed compared to that of the free electron. If the relative transverse momentum of the virtual electron and photon is large compared with the electron mass, the virtual electron and photon each carry nearly the total angular momentum of the physical electron (1/2), with the orbital angular momentum being nearly (-1/2). Including the non-zero photon mass leads to the suppression of end-point contributions to form factors. Implications for proton structure and color transparency are discussed.
description: 20 pages, 10 figures
Precision characterization of three ultrafine condensation particle counters using singly charged salt clusters in the 1-4 nm size range generated by a bipolar electrospray source
Creators: name: Brilke, Sophia
name: Resch, Julian
name: Leiminger, Markus
name: Steiner, Gerhard
name: Tauber, Christian
name: Wlasits, Peter J.
name: Winkler, Paul M.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Molecular singly charged clusters generated by electrospray sources are commonly used for calibration measurements of ultrafine Condensation Particle Counters (CPCs) in the sub-2 nm size range. This technique has been limited to the smallest singly charged clusters. In this study, we used a bipolar electrospray source combining two electrosprays of opposite polarities to generate singly charged clusters of ammonium salts dissolved in acetonitrile, i.e. tetra-heptyl ammonium bromide (THABr) and tetra-butyl ammonium iodide (TBAI) clusters. A high-resolution UDMA acts as a classifier for positively and negatively charged clusters which are used as mobility standards for the measurement of the complete ascent of the detection efficiency curve of three ultrafine CPCs. The CPCs characterized in this work are two laminar flow-type CPCs using n-butanol (TSI UCPC Model 3776, TSI Inc., Minneapolis, USA) and diethylene glycol (DEG) (TSI UCPC Model 3777, TSI Inc., Minneapolis, USA) as working fluid and the turbulent mixing-type DEG-based Particle Size Magnifier (Airmodus A10 PSM). The clusters generated by the bipolar electrospray source are analyzed for their elemental composition using the Atmospheric Pressure interface Time-Of-Flight mass spectrometer (ioniAPi-TOF, Ionicon Analytik GmbH, Austria) in positive and negative ion mode. We present mobility-dependent mass spectra from experiments using the UDMA and the ioniAPi-TOF in series for the analysis of positively charged clusters when operating the electrospray source in unipolar and in bipolar mode to demonstrate the charge reduction and purity of the sample. Copyright © 2019 American Association for Aerosol Research
Propylene hydrogenation on pt/α-Al2O3, pd/α-Al2O3, pt/ZrO2, and pd/ZrO2 in the presence of H2O: experimental and modeling study
Creators: name: Suzuki, Shunsuke
name: Uchisawa, Junko
name: Obuchi, Akira
name: Yamamoto, Asuka
name: Sakai, Toshihiko
name: Nagata, Makoto
name: Yoshimura, Masatoshi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology

description: Liquefied petroleum gas (LPG) is known as clean fuel and its importance will be continued in the future. However, most of LPG is currently produced from fossil resources. Thus, producing LPG from CO2 as a renewable source is significant for achieving carbon neutrality. One possible way to produce LPG from CO2 is through an indirect pathway via methanol/dimethyl ether and propylene/butene. The final step of this pathway is the hydrogenation reaction of olefins to produce paraffins. Although H2O may coexist in this reaction, there have been few studies to investigate reaction kinetics of propylene hydrogenation in the presence of H2O. Here, we measured the propylene conversion over different four catalysts: Pt/α-Al2O3, Pd/α-Al2O3, Pt/ZrO2, and Pd/ZrO2. We varied a reaction temperature and concentrations of propylene, H2 and H2O in the feed. We found that above 200 °C the propylene conversion was negatively affected by the reaction temperature and the propylene concentration, while it was positively affected by the H2 concentration. We also found that the dependence of propylene conversion on H2O concentration depended on the catalysts. To reproduce the measured results, a kinetic model based on the Langmuir-Hinshelwood mechanism was developed over Pt/ZrO2 which showed the best reaction performance among the catalysts used. A two-dimensional reactor model consisting of mass and heat balance equations was developed for exploring the desirable reactor type. The simulations showed that the externally cooled reactor with a catalyst density gradient was the most suitable for propylene hydrogenation in terms of heat management and propylene conversion.
Don’t Forget ADAS Recalibration After a Windshield Replacement
Creators: name: Aguirre, Isabel
Publisher: name: figshare
Year: 2023
Subjects: Commercial services not elsewhere classified

description: The windshield is one of a car's most important safety features because it protects the driver from the weather and keeps debris from getting into the car. But when a windshield is replaced, the Advanced Driver Assistance System (ADAS) must be reset. With correct calibration of the ADAS, the car's safety and the driver's ability to control it can be protected. This article will talk about how important it is to recalibrate ADAS after getting a new windshield and what could happen if you don't.
title: Exploring novel mechanisms underlying synovial fibroblast-mediated pathogenesis in arthritis: role of ARNO and sialylation in stromal inflammation
Creators: name: Wang, Yilin
Publisher: name: University of Glasgow
Year: 2022

description: Synovial fibroblasts (SFs) not only maintain articular homeostasis in a health state, but also play a key role in joint destruction in immune articular diseases, such as rheumatoid arthritis (RA). In RA, activated SFs undergo intrinsic alterations, adopting an aggressive phenotype that damages cartilage and bone. The dysregulated cell migratory property and hyper-inflammatory responses are hallmarks of activated SFs. However, deactivation of these cells is not currently possible. This study investigated two potential novel sites of invention, namely defining the ARNO and Sialic acid arms of the project. The central aim of this study was to understand the regulation of ARNO and sialic acid in SFs in a proinflammatory microenvironment and the function of ARNO and sialic acid in SF-dependent migration and inflammation. On the one hand, ARNO (the ARF Nucleotide-Binding Site Opener) is a dominant activator of ARF (ADP-ribosylation factor) proteins that regulate cell adhesion, migration, and cytoskeleton reorganisation in many cell types. The elevated expression of ARNO in leukocyte-rich RA shows ARNO might be regulated in a pro-inflammatory milieu, indicating the potential role of ARNO in SF-dependent physiopathology. We demonstrated that IL-1β upregulated ARNO expression and ARF6 activation in SFs, whilst SFs transfected with ARNO siRNA exhibited reduced motility and formation of focal adhesion. Surprisingly therefore, ARNO modulated the IL-1β-induced inflammatory response in SFs and the inhibition of ARNO greatly reduced the production of cytokines, chemokines and other immunomodulators. On the other hand, glycosylation is one of the most common protein modifications, and the glycoconjugates on plasma membranes are involved in a wide range of biological functions, including cell-cell interactions and inflammation. Alterations in glycosylation have been observed in chronic diseases, but how changes in the cell glycome affect SF physiopathology remains largely unknown. We combined transcriptomic and glycomics analysis to investigate glycosylation-dependent SF physiopathology. We demonstrated that the pro-inflammatory cytokine TNFα modulates SF cell surface glycosylation by inhibiting the expression of ST6Gal1 and subsequently reducing α2-6 sialylation. In addition, SFs from arthritic mice exhibited reduced cell surface sialylation and sialylation was associated with functional SF subsets. Removal of cell surface sialic acid with sialidase from C. perfringens provided evidence that loss of sialic acid transforms SF into a pathogenic phenotype with hyper-inflammatory response and enhanced migration property. Overall, this work highlights the importance of ARNO and sialic acid in SFmediated inflammation and pathogenic migration, bridging cell motility to inflammatory responses, and offering new perspective on targeting SF deactivation in arthritic joints.
Physiological parameters as a key tool for understanding and optimizing yeast metabolism and physiology in batch cultures
Creators: name: Silva, Cinthia Aparecida Andrade
name: Fonseca, Gustavo Graciano
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Yeasts, as versatile microorganisms, play a vital role in numerous biotechnological applications, including biofuel production, food and beverage fermentation, and pharmaceutical manufacturing. To harness their full potential, it is crucial to understand the kinetics of yeast metabolism and physiology. This review highlights the importance of physiological parameters in assessing yeast behavior under different batch culture conditions. Key parameters such as maximum specific growth rate (μmax), specific substrate consumption rate (μS), yields (YX/S and YP/S), and productivities (PX and PP) provide valuable insights into yeast utilization and production of organic compounds. By compiling data on physiological parameters for different yeast strains grown under diverse conditions, researchers can identify optimal genetic modifications, pathway constructions, strain selections, substrate choices, and culture conditions. This knowledge enables the bridging of the gap between laboratory-scale experiments and industrial applications, facilitating the development of efficient and sustainable bioprocesses. Physiological parameters serve as a practical tool for optimizing yeast-based biotechnological processes.
Dual Basis Functions in Subspaces
Creators: name: Kersey, Scott N.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 41A05, 41A10, 41A15, 65D05 65D07

description: In this paper we study dual bases functions in subspaces. These are bases which are dual to functionals on larger linear space. Our goal is construct and derive properties of certain bases obtained from the construction, with primary focus on polynomial spaces in B-form. When they exist, our bases are always affine (not convex), and we define a symmetric configuration that converges to Lagrange polynomial bases. Because of affineness of our bases, we are able to derive certain approximation theoretic results involving quasi-interpolation and a Bernstein-type operator. In a broad sense, it is the aim of this paper to present a new way to view approximation problems in subspaces. In subsequent work, we will apply our results to dual bases in subspaces of spline and multivariate polynomial spaces, and apply this to the construction of blended function approximants used for approximation in the sum of certain tensor product spaces.
description: 21 pages, 2 figures
Random strings and tt-degrees of Turing complete C.E. sets
Creators: name: Cai, Mingzhong
name: Downey, Rodney G
name: Epstein, Rachel
name: Lempp, Steffen
name: Miller, Joseph
Publisher: name: arXiv
Year: 2014
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: We investigate the truth-table degrees of (co-)c.e.\ sets, in particular, sets of random strings. It is known that the set of random strings with respect to any universal prefix-free machine is Turing complete, but that truth-table completeness depends on the choice of universal machine. We show that for such sets of random strings, any finite set of their truth-table degrees do not meet to the degree~0, even within the c.e. truth-table degrees, but when taking the meet over all such truth-table degrees, the infinite meet is indeed~0. The latter result proves a conjecture of Allender, Friedman and Gasarch. We also show that there are two Turing complete c.e. sets whose truth-table degrees form a minimal pair.
description: 25 pages
Meta-heuristic optimization for drying kinetics and quality assessment of Capparis spinosa buds
Creators: name: Lakhdari, Chafika
name: Remini, Hocine
name: Benzitoune, Nourelimane
name: Djellal, Samia
name: Hentabli, Mohamed
name: Adouane, Meriem
name: Dahmoune, Farid
name: Kadri, Nabil
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: This paper was conducted to model the drying kinetics of Capparis spinosa buds using dragonfly swarm optimized nonlinear regression and to compare the impact of drying treatments on their quality. Experiments included hot-air convective drying (HACD) from 40 to 120 °C, vacuum drying (VD) at 40, 60, and 80 °C, microwave drying (MD) ranging from 200 to 1000 W. Out of 30 models tested, the drying kinetics fitted best with Jena Das model in both HACD and VD and modified Midilli for MD. The comparison between the drying treatments used indicated that when taking into account the quality of the dried caper, VD at 80 °C was the most effective, resulting in a high-quality caper with a well-preserved color (ΔE = 7.47), high bioactives (TPC = 30.18mgGAE/gDW and TFC = 10.27 mg QE/gDW) and radical scavenging abilities (DPPH = 0.249 and ABTS = 4.448 mg/mL) at the expense of long duration (6h) and high specific energy consumption (50.667 kWh/kg). On the other hand, when considering the drying behavior MD ranked best with samples dried at 1000 W showing high diffusivities 2.04e−8 m2s−1 low energy consumption (MER 0.1216 kg/h), and short drying times (12 mn). This research is critical in selecting better drying conditions for increased usage in the culinary, cosmetic, and pharmaceutical sectors.
Computer simulation of the dynamics of hydrated protein crystals and its comparison with x-ray data.
Creators: name: Postma, J. P.
name: Hol, W. G.
name: Hermans, J.
name: van Gunsteren, W. F.
name: Berendsen, H. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: The structure and dynamics of the full unit cell of a protein (bovine pancreatic trypsin inhibitor) containing 4 protein molecules and 560 water molecules have been simulated by using the molecular dynamics method. The obtained structure, atom positional fluctuations, and structure factors are compared with x-ray values. A way of calculating the motional contributions to structure factors is proposed.
HIGHz: A Survey of the Most HI-Massive Galaxies at z~0.2
Creators: name: Catinella, Barbara
name: Cortese, Luca
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results of the HIGHz Arecibo survey, which measured the HI content of 39 galaxies at redshift $z>0.16$ selected from the Sloan Digital Sky Survey. These are all actively star-forming, disk-dominated systems in relatively isolated environments, with stellar and HI masses larger than $10^{10}$ M$_\odot$ and redshifts $0.17\leq z\leq 0.25$. Our sample includes not only the highest-redshift detections of HI emission from individual galaxies to date, but also some of the most HI-massive systems known. Despite being exceptionally large, the HI reservoirs of these galaxies are consistent with what is expected from their ultraviolet and optical properties. This, and the fact that the galaxies lie on the baryonic Tully-Fisher relation, suggests that HIGHz systems are rare, scaled-up versions of local disk galaxies. We show that the most HI-massive galaxies discovered in the Arecibo Legacy Fast ALFA survey are the local analogues of HIGHz, and discuss the possible connection between our sample and the turbulent, gas-rich disks identified at $z\sim 1$. The HIGHz sample provides a first glimpse into the properties of the massive, HI-rich galaxies that will be detected at higher redshifts by the next-generation HI surveys with the Square Kilometer Array and its pathfinders.
description: 20 pages, 11 figures, 3 tables. Accepted for publication in MNRAS. Version with high resolution figures available at http://astronomy.swin.edu.au/~bcatinel/publications.htm
CLS INFRA Poster Presentation DH2022 Tokyo
Creators: name: Birkholz, Julie
name: Börner, Ingo
name: Chambers, Sally
name: Charvat, Vera
name: Cinková, Silvie
name: Van Dalen-Oskam, Karina
name: Dejaeghere, Tess
name: Dudar, Julia
name: Ďurčo, Matej
name: Edmond, Jennifer
name: Evgeniia Fileva
name: Fischer, Frank
name: Heiden, Serge
name: Křen, Michal
name: Bartłomiej Kunda
name: Michał Mrugalski
name: Murphy, Ciara
name: Odebrecht, Carolin
name: Raciti, Marco
name: Ros, Salvador
name: Schöch, Christof
name: Šeļa, Artjoms
name: Tasovac, Toma
name: Tonra, Justin
name: Tóth-Czifra, Erzsébet
name: Trilcke, Peer
name: Eder, Maciej
name: Van Rossum, Lisanne M.
Publisher: name: Zenodo
Year: 2022
Subjects: Infrastructure
Computational Literary Studies
Research practice

description: Computational Literary Studies Infrastructure, funded by the Horizon2020 grant scheme, is a four-year, pan-European project that aims to unify the diverse landscape of computational text analysis, in terms of available texts, tools, methods, practices and so forth, within its growing international user community. The project started out in February 2021, meaning that it has been underway for just over a year. In our poster we discuss the various deliverables and activities that have come out of the CLS INFRA project in its first quarter to give an idea of its impact in practice.
Hans Heinrich Landolt
Creators: name: Pribram, Richard
Publisher: name: Zentralbibliothek Zürich
Year: 1911
Subjects: subject: 540 Chemie
subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Landolt, Hans
subject: Zürich
subject: Berlin

description: Sonderabdruck aus Band XXXXIV der Berichte der Deutschen Chemischen Gesellschaft
Detection of autonomous replicating sequences (ars) in the genome of Epstein-Barr virus.
Creators: name: Raab-Traub, N. J.
name: Pagano, J. S.
name: Henry, B. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Epstein-Barr virus (EBV) DNA was analyzed for the presence of autonomous replicating sequences (designated ars) in a eukaryotic system consisting of a uracil auxotroph of Saccharomyces cerevisiae, YNN27, and a pBR322 hybrid plasmid, YIp5, containing the yeast uracil gene but apparently lacking a eukaryotic origin of replication. Cloned EBV DNA EcoRI restriction fragments, A, B, and DIJhet, were judged to function in this capacity by their ability to convert YNN27 cells to the uracil phenotype after transformation with each EBV-specific fragment ligated into YIp5. Additional analyses to confirm and to specify further the location of the ars were performed by cleavage of EcoRI fragments A and B into smaller BamHI fragments, which were subsequently cloned in YIp5 and tested for their ability to function as ars. BamHI fragment X, obtained from EcoRI fragment A, and BamHI fragment R, obtained from EcoRI fragment B, showed ars behavior. The successful recovery of the appropriate virus DNA segments in plasmid form from transformed yeast cells and the ability of these yeast cells to be propagated further substantiated the ars capability of the three EBV fragments.
Dialyzable factor in human serum of platelet origin stimulates endothelial cell replication and growth
Creators: name: Clemmons, D. R.
name: Isley, W. L.
name: Brown, M. T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Porcine aortic endothelial cells were isolated and maintained in Dulbecco's modified Eagle's medium (DME medium)/10% citrate-treated human plasma. They were stimulated by DME medium/10% human serum to grow from a density of 10,100 +/- 500 per well to a final density of 83,000 +/- 1,800 per well over a 9-day period. On the other hand these cells grew poorly (11% increase) in DME medium/10% human platelet-poor plasma prepared without chelating agents and containing platelet factor 4 at 18 ng/ml by radioimmunoassay. Dialysis of the human serum (M(r) cutoff, 3,500) eliminated all the stimulatory activity. The activity recovered from the dialysate stimulated growth when added to endothelial cultures in conjunction with either dialyzed serum or platelet-poor plasma alone. The dialyzable factor could be obtained directly from platelets; both acetic acid extracts and boiled NaCl extracts stimulated porcine aortic endothelial cell replication. Gel filtration chromatography on Sephadex G-15 showed that the endothelial growth factor had a molecular weight of 700. Partially purified material induced a concentration-dependent stimulation of porcine aortic endothelial cell replication in the presence of DME medium alone; however, simultaneous incubation with platelet-poor plasma resulted in a much greater response. Fibroblast growth factor isolated from bovine brain was found to be mitogenic only in the presence of nondialyzed serum or of the dialyzable factor together with plasma. In the absence of this serum factor, fibroblast growth factor had no effect. We conclude that human serum contains a potent endothelial cell mitogen of platelet origin. Human plasma that is devoid of platelet content does not stimulate endothelial cell growth. This growth factor may be an important stimulant of the endothelial cell response to vascular wall injury.
Fire and ice : understanding volcanic histories from sulfur isotopes in ice cores
Creators: name: Crick, Laura
Publisher: name: The University of St Andrews
Year: 2023
Subjects: subject: Volcanism
subject: Ice cores
subject: Sulfur isotopes
subject: Mass-independent fractionation
subject: Photochemical model
subject: QE522.C8
subject: Volcanism
subject: Ice cores
subject: Sulfur--Isotopes

description: Reconstructing the history of explosive volcanic eruptions is important for understanding the frequency of eruptions and the climatic forcing of these events. Erupted volcanic SO₂ is oxidised to sulfate aerosols which scatter incoming solar radiation. Aerosols are then deposited at the poles resulting in a peak in sulfate above background concentrations. Therefore, polar ice cores provide an important record of volcanism. The mass-independent fractionation of sulfur isotopes (S-MIF) in ice cores is an indicator of sulfur exposure to ultraviolet radiation via eruption into and above the ozone layer in the stratosphere. Sulfate aerosols from large eruptions that reach the stratosphere have a longer residence time and greater climatic impact than tropospheric aerosols from smaller eruptions. In this thesis I measure sulfur isotopes in volcanic ice core sulfate to investigate the ~74ka Toba supereruption and six unidentified volcanic eruptions from 16ka to 32ka. I found large magnitude S-MIF signals (-4.75‰) for one of the Toba candidates, the timing of which is consistent with independent age estimates for Toba. This places the eruption on the transition into a cool stadial period in Greenland (GS-20). Toba can be excluded as a potential trigger for GS-20, although it could have contributed to the cooling. To help interpret the six eruptions from 16–32ka, I adapted a 1D-diffusion model to simulate the diffusion and thinning of sulfate isotopes in ice cores. I found that the ice core sulfate isotope signatures are consistent with modelled results of sulfate exposed to diffusion and thinning. Finally, I adapted a 1D-photochemical model (Atmos) to model the temporal evolution of sulfur isotope signatures in a volcanic plume. The model predicts S-MIF signatures consistent in timing and shape to those measured in the ice cores for stratospheric eruptions with S-MIF formation primarily via self-shielding due to high SO₂ column densities.
Evidence for extensive polymorphism of class I genes in the rat major histocompatibility complex (RT1).
Creators: name: Palmer, M.
name: Wettstein, P. J.
name: Frelinger, J. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: The major histocompatibility complex of the rat (RT1) has been poorly characterized with respect to the number, linkage, and polymorphism of class I genes. To estimate the number of class I RT1 genes and the relative extent of their polymorphism, we performed Southern blot analysis with liver DNA from rat strains expressing eight RT1 haplotypes. After digestion with EcoR1 and BamHI, the DNA was separated on agarose gels, blotted onto nitrocellulose, and hybridized with mouse H-2 cDNA probes, pH-2III and pH-2IIa. Ten to 20 EcoRI and 13 to 20 BamHI bands hybridized with pH-2III and pH-2IIa; restriction fragment length patterns were observed to be highly polymorphic. The restriction fragments associated with different RT1 haplotypes differed by 17-70%; this range is similar to the differences observed between mouse H-2 haplotypes. The same restriction fragment pattern was observed in DNA from three different rat strains sharing the same RT1 allele, confirming that the patterns were RT1-associated. Further, the RT11 and RT11v1 haplotypes, which differ at a single previously identified RT1-linked locus, were associated with EcoRI restriction pattern differences of 39-50%, confirming the supposition that RT1 class I genes identified by previous serological and T-cell-mediated assays have identified only a minority of the actual number of RT1-linked class I genes. In summary, the results reported in this communication demonstrate that the RT1 complex encompasses a large family of highly polymorphic class I genes similar to the H-2 and HL-A complexes of mouse and man.
Simulative Untersuchung zum Energiebedarf einer schreitenden Forstmaschine
Creators: name: Beiser, Sebastian
name: Wydra, Marco
name: Geimer, Marcus
Publisher: name: KIT Scientific Publishing
Year: 2023
Subjects: Portalschreitwerk
Co-Simulation
Hydraulik
Forsttechnik

description: Dieser Beitrag zeigt eine Möglichkeit auf, den Energiebedarf für das Voranschreiten eines Portalschreitwerks in einem frühen Stadium der Entwicklung abzuschätzen. Hierfür wird eine gekoppelte Simulation, bestehend aus Mehrkörper- und Hydraulikmodell aufgebaut. Zunächst wird die Bewegungs- und Steuerungsabfolge in der Ebene beschrieben. Die Abfolge wird für die Simulation in drei Teilbewegungen unterteilt. Diese werden jeweils mit vereinfachten Randbedingungen durchgeführt. Die Simulationen zeigen, dass für einen Bewegungszyklus eine Energie von 174 Wh benötigt wird, woraus sich ein Dieselverbrauch von 0,77 ... 0,87 l/100 m ableiten lässt.
title: The spatiotemporal nature of market making
title: Insights from the favela tourism market in Rocinha
titleType: Subtitle
Creators: name: Fernandes, Josi
Publisher: name: Lancaster University
Year: 2022
Subjects: markets
Actor-Network Theory
space
Digital

description: The present thesis is concerned with the spatiotemporal nature of market-making practices. While previous literature on markets has explored the socio-material arrangements that enable the creation and performance of markets, less attention has been granted to the role that spatiality and temporality play in these arrangements and in overcoming barriers to market-making. The market studies literature has indicated that markets have a spatiotemporal dimension through notions such as that of situated practice and markets in the making (Cochoy, 2008; Mason et al., 2015; Palo et al., 2018; Stigzelius et al., 2018) and early works on time (Araujo and Easton, 2012; Easton and Araujo, 1994; Kavanagh and Araujo, 1995). Yet, these matters have not formed a central concern when seeking to understand market formation. Anchored in and combining the markets literature and its theoretical underpinning (e.g., Callon, 1998; Latour, 2005) with ideas from social theory (e.g., Lefebvre, 1991), the present thesis addresses these gaps and contributes to a more nuanced understanding of markets that includes a spatial and temporal dimension to the socio-material arrangements that make them (cf. Araujo, 2007). The insights contained in this thesis are derived from the research of favela-based local entrepreneurs in Rio de Janeiro, Brazil, between 2016 and 2019. It is comprised of three papers, each adopting a different analytical lens. The first paper starts from the concept of stigma (Goffman, 1963; Wacquant, 2007) and, through a market studies approach, unpacks the temporally bounded agencements (Callon, 2016; Cochoy et al., 2016) that enabled the successful making of the favela tourism market. The second paper analyses the practices of favela local entrepreneurs to remake the market agencement after the breakout of a conflict in the favela through the lenses of Lefebvre’s (1991) spatial theory. Papers 1 and 2 revealed the importance of digital technologies in the market practices of favela entrepreneurs and spurred the ideas for the third and final paper of this thesis. The third paper is a methodology-oriented discussion where I reflect on my engagement with the technologically enmeshed Rocinha favela during my fieldwork and on the role of digital technologies in research practices and consequently, in knowledge production.
Follicle-stimulating hormone-dependent phosphorylation of vimentin in cultures of rat Sertoli cells.
Creators: name: Kierszenbaum, A. L.
name: Steiner, A. L.
name: Tres, L. L.
name: Spruill, W. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Endogenous protein phosphorylation was investigated in cultured rat Sertoli cells after treatment with follicle-stimulating hormone (FSH) and pharmacological agents that activate cAMP-dependent protein kinases. In intact Sertoli cells, both phosphorylation and dephosphorylation of proteins occurred in response to treatment with these agents. Studies using cell-free preparations suggest that four phosphoproteins phosphorylated by cAMP or the catalytic subunit of cAMP-dependent protein kinase were also phosphorylated in a FSH-dependent manner in intact cells. These data suggest that FSH-dependent phosphorylation in Sertoli cells occurs through activation of a cAMP-dependent protein kinase. A FSH-dependent phosphoprotein with a molecular weight of 58,000 was identified as the intermediate filament protein vimentin, based on its migration in two-dimensional gels and its peptide map. The cellular distribution of vimentin was monitored by immunofluorescence in Sertoli cells after treatment with FSH. Results of this study support a role for intermediate filaments in FSH-dependent events in Sertoli cells.
title: Marine climate change impacts: Implications for the implementation of marine biodiversity legislation
Creators: name: MCCIP
Publisher: name: Marine Climate Change Impacts Partnership (MCCIP), Lowestoft, UK
Year: 2015

description: This Report Card looks at climate change and marine biodiversity legislation, with a focus on the legislation used to establish various types of marine protected areas.
description: MCCIP Special Topic Report Card 2015
Towards Quantum Simulating QCD
Creators: name: Wiese, Uwe-Jens
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum link models provide an alternative non-perturbative formulation of Abelian and non-Abelian lattice gauge theories. They are ideally suited for quantum simulation, for example, using ultracold atoms in an optical lattice. This holds the promise to address currently unsolvable problems, such as the real-time and high-density dynamics of strongly interacting matter, first in toy-model gauge theories, and ultimately in QCD.
description: 8 pages, 4 figures, plenary talk at Quark Matter 2014, submitted as a proceedings contribution to Nuclear Physics A
title: Effeithiau newid hinsawdd ar y môr: Goblygiadau ar gyfer gweithredu deddfwriaeth bioamrywiaeth y môr
Creators: name: MCCIP
Publisher: name: Marine Climate Change Impacts Partnership (MCCIP), Lowestoft, UK
Year: 2015

description: Mae’r Cerdyn Adrodd hwn yn edrych ar ddeddfwriaeth newid hinsawdd a bioamrywiaeth forol, gan ganolbwyntio ar y ddeddfwriaeth a ddefnyddir i sefydlu gwahanol fathau o ardaloedd gwarchodedig morol.
description: MCCIP Special Topic Report Card 2015
Heparin-catalyzed inhibitor/protease reactions: kinetic evidence for a common mechanism of action of heparin.
Creators: name: Griffith, M. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Three different heparin-catalyzed inhibitor/protease reactions were studied: antithrombin III/thrombin, heparin cofactor II/thrombin, antithrombin III/factor Xa. The three reactions were saturable with respect to both inhibitor and protease. The initial reaction velocity, for each reaction, could be described by the general rate equation for a random-order bireactant enzyme-catalyzed reaction. The kinetic parameters for the heparin-catalyzed antithrombin III/thrombin and antithrombin III/factor Xa reactions differed in terms of apparent maximum velocity (Vmax) and apparent heparin-protease dissociation constant values. The apparent heparin-antithrombin III dissociation constant values were the same for both reactions. The kinetic parameters for the heparin-catalyzed antithrombin III/thrombin and heparin cofactor II/thrombin reactions differed in terms of apparent Vmax and apparent heparin-inhibitor dissociation constant values. The apparent heparin-thrombin dissociation constant values were the same for both reactions. The results are consistent with a general mechanism of action of heparin for the three reactions that, in its simplest form, requires only that both protease and inhibitor bind to heparin for catalysis to occur.
Turbo Compressed Sensing with Partial DFT Sensing Matrix
Creators: name: Ma, Junjie
name: Yuan, Xiaojun
name: Ping, Li
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this letter, we propose a turbo compressed sensing algorithm with partial discrete Fourier transform (DFT) sensing matrices. Interestingly, the state evolution of the proposed algorithm is shown to be consistent with that derived using the replica method. Numerical results demonstrate that the proposed algorithm outperforms the well-known approximate message passing (AMP) algorithm when a partial DFT sensing matrix is involved.
description: IEEE Signal Processing Letters, (Volume:22, Issue: 2), Feb. 2015
High-affinity binding of agonists to beta-adrenergic receptors on intact cells.
Creators: name: Toews, M. L.
name: Perkins, J. P.
name: Harden, T. K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: The interactions of agonists and antagonists with beta-adrenergic receptors on intact 1321N1 human astrocytoma and C62B rat glioma cells were studied by using the radioligand (-)-[125I]iodopindolol. Competition binding assays were performed at 37 degrees C under equilibrium conditions and in short-time nonequilibrium assays that approximated initial velocity conditions for binding of the radioligand. The theoretical basis and experimental validation of the initial velocity approach for determining binding affinities of rapidly equilibrating ligands are presented. For the agonists isoproterenol and epinephrine, high binding affinities that approximated their apparent affinities for binding in membranes and for increase of cyclic AMP concentrations in intact cells could be demonstrated only in short-time assays; in contrast, much lower affinities were observed with equilibrium (60-min) assays as reported previously for various cell lines. High-affinity binding of isoproterenol to 1321N1 cells also was observed in equilibrium (6-hr) binding assays carried out on ice. These results indicate that in the native state the intact cell beta-adrenergic receptor has a high binding affinity for agonists and suggest that incubation at 37 degrees C in the presence of an agonist converts the receptors to a form with low affinity for agonists.
Zero modes in vortex-fermion system with compact extra space
Creators: name: Nakamula, A.
name: Shiraishi, K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The existence of fermionic zero modes is shown in the presence of vortex configuration of pure $SU(2)$ gauge field on the manifold $M_4 \times S^2$. From the perspective of four-dimensional effective theory, these zero modes are almost the same as the Jackiw-Rossi type zero modes of the vortex-fermion system.
description: 9 pages, no figure
Ordered and disordered phospholipid domains coexist in membranes containing the calcium pump protein of sarcoplasmic reticulum.
Creators: name: Meissner, G.
name: Clubb, K. W.
name: Lentz, B. R.
name: Barrow, D. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Data are presented that lead to an alternative model for the organization and molecular dynamics of lipid molecules near the Ca2+-stimulated, Mg2+-dependent adenosinetriphosphatase (Ca2+-ATPase; ATP phosphohydrolase, EC 3.6.1.3) of sarcoplasmic reticulum. Measurements of the steady-state fluorescence anisotropy of 1,6-diphenyl-1,3,5-hexatriene in progressively delipidated sarcoplasmic reticulum membranes have been quantitatively interpreted in terms of a layer of lipid of high anisotropy (the lipid annulus) coexisting with lipid layers of very low anisotropy. In addition, the Ca2+-ATPase has been reconstituted into pure 1,2-dipentadecanoyl 3-sn-phosphatidylcholine membranes over a range of lipid-to-protein ratios. High-sensitivity differential scanning calorimetry has demonstrated that roughly 30 lipid molecules per Ca2+-ATPase molecule (annular lipids) fail to undergo a calorimetrically detectable phase transition in the temperature range 4-44 degrees C. Roughly 100 lipid molecules beyond the annulus undergo a detectable phase transition at a temperature below the phase transition of pure lipid and with an enthalpy change [4.2 kcal/mol (1 kcal = 4.18 kJ)] about half that observed for pure lipid vesicles (7.7-7.8 kcal/mol). We propose that both the fluorometric and calorimetric data are consistent with a model in which a motionally inhibited lipid annulus is surrounded by a more extensive region of disrupted lipid packing order, which we have called the secondary lipid domain.
Microwave degenerate parametric down-conversion with a single cyclic three-level system in circuit QED
Creators: name: Wang, Z. H.
name: Sun, C. P.
name: Li, Yong
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: With the assistance of a single cyclic three-level system, which can be realized by a superconducting flux qubit, we study theoretically the degenerate microwave parametric down-conversion (PDC) in a superconducting transmission line resonator with the fundamental and second harmonic modes involved. By adiabatically eliminating the excited states of the three-level system, we obtain an effective microwave PDC Hamiltonian for the two resonator modes in such a circuit QED system. The corresponding PDC efficiency in our model can be much larger than that in the similar circuit QED system based on a single two-level superconducting qubit [K. Moon and S. M. Girvin, Phys. Rev. Lett. {\bf 95}, 140504 (2005)]. Furthermore, we consider the squeezing and bunching behavior of the fundamental mode resulting from the coherent drive to the second harmonic one.
description: 6 pages, 4 figures submitted to Phys. Rev. A
Permanent cell line expressing human factor VIII-related antigen established by hybridization.
Creators: name: Edgell, C. J.
name: Graham, J. B.
name: McDonald, C. C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: A permanent human cell line, EA .  hy 926, has been established that expresses at least one highly differentiated function of vascular endothelium, factor VIII-related antigen. This line was derived by fusing human umbilical vein endothelial cells with the permanent human cell line A549. Hybrid cells that survived in selective medium had more chromosomes than either progenitor cell type and included a marker chromosome from the A549 line. Factor VIII-related antigen can be identified intracellularly in the hybrids by immunofluorescence and accumulates in the culture fluid. Expression of factor VIII-related antigen by these hybrid cells has been maintained for more than 100 cumulative population doublings, including more than 50 passages and three cloning steps. This is evidence that EA . hy 926 represents a permanent line.
CHARIS Science: Performance Simulations for the Subaru Telescope's Third-Generation of Exoplanet Imaging Instrumentation
Creators: name: Brandt, Timothy D.
name: McElwain, Michael W.
name: Janson, Markus
name: Knapp, Gillian R.
name: Mede, Kyle
name: Limbach, Mary Anne
name: Groff, Tyler
name: Burrows, Adam
name: Gunn, James E.
name: Guyon, Olivier
name: Hashimoto, Jun
name: Hayashi, Masahiko
name: Jovanovic, Nemanja
name: Kasdin, N. Jeremy
name: Kuzuhara, Masayuki
name: Lupton, Robert H.
name: Martinache, Frantz
name: Sorahana, Satoko
name: Spiegel, David S.
name: Takato, Naruhisa
name: Tamura, Motohide
name: Turner, Edwin L.
name: Vanderbei, Robert
name: Wisniewski, John
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We describe the expected scientific capabilities of CHARIS, a high-contrast integral-field spectrograph (IFS) currently under construction for the Subaru telescope. CHARIS is part of a new generation of instruments, enabled by extreme adaptive optics (AO) systems (including SCExAO at Subaru), that promise greatly improved contrasts at small angular separation thanks to their ability to use spectral information to distinguish planets from quasistatic speckles in the stellar point-spread function (PSF). CHARIS is similar in concept to GPI and SPHERE, on Gemini South and the Very Large Telescope, respectively, but will be unique in its ability to simultaneously cover the entire near-infrared $J$, $H$, and $K$ bands with a low-resolution mode. This extraordinarily broad wavelength coverage will enable spectral differential imaging down to angular separations of a few $λ/D$, corresponding to $\sim$$0.\!\!''1$. SCExAO will also offer contrast approaching $10^{-5}$ at similar separations, $\sim$$0.\!\!''1$--$0.\!\!''2$. The discovery yield of a CHARIS survey will depend on the exoplanet distribution function at around 10 AU. If the distribution of planets discovered by radial velocity surveys extends unchanged to $\sim$20 AU, observations of $\sim$200 mostly young, nearby stars targeted by existing high-contrast instruments might find $\sim$1--3 planets. Carefully optimizing the target sample could improve this yield by a factor of a few, while an upturn in frequency at a few AU could also increase the number of detections. CHARIS, with a higher spectral resolution mode of $R \sim 75$, will also be among the best instruments to characterize planets and brown dwarfs like HR 8799 cde and $κ$ And b.
description: 13 pages, 7 figures, proceedings from SPIE Montreal
Quantitative correlation of homogeneously stained regions on chromosome 10 with dihydrofolate reductase enzyme in human cells.
Creators: name: Craven, M. L.
name: Grill, S. P.
name: Cheng, Y. C.
name: Domin, B. A.
name: Wolman, S. R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Gene amplification may be visualized within a chromosome as a homogeneously stained region (HSR) and HSRs have rarely been reported in human tumor cells with identification of the amplified gene. A parental line and seven clones derived from KB cells resistant to methotrexate (MTX) contain dihydrofolate reductase (DHFR; tetrahydrofolate dehydrogenase; EC 1.5.1.3), ranging from 0.007 unit/mg in the parent to 0.369 unit/mg in clone 7A with a 13,000-fold increase in resistance to MTX. The enzyme is identical to DHFR from other human sources, including that from leukemic patients. A HSR localized to the long arm of chromosome 10(q26) is present in clones selected at or above 2.5 microM MTX. Increase in number of 10q per cell, increase in number of HSR, and increasing amounts of DHFR correlate well. The chromosome change is stable with time as is enzyme production even in the absence of selection by MTX. No clone has shown double minutes. The gene copy number is low. The stability and low gene copy in the presence of large HSRs differ from the pattern described for murine tumors. A human gene for DHFR may be associated with the long arm of chromosome 10.