Additional file 1 of Synthesis, in silico studies and biological screening of (E)-2-(3-(substitutedstyryl)-5-(substitutedphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole derivatives as an anti-oxidant, anti-inflammatory and antimicrobial agents
Creators: name: Kumar, Manoj
name: Kumar, Vijay
name: Singh, Vikramjeet
name: Thakral, Samridhi
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Hematology

description: Additional file 1: Fig. S1. IR spectra of compound Z1 [(E)-2-(3-(4-chlorostyryl)-5-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S2. 1H NMR spectra of compound Z1 [(E)-2-(3-(4-chlorostyryl)-5-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S3. 13C NMR spectra of compound Z1 [(E)-2-(3-(4-chlorostyryl)-5-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S4. IR spectra of compound Z2 [(E)-2-(3-(3-chlorostyryl)-5-(3-chlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S5. IR spectra of compound Z3 [(E)-2-(3-(3-nitrostyryl)-5-(3-nitrophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S6. 1H NMR spectra of compound Z3 [(E)-2-(3-(3-nitrostyryl)-5-(3-nitrophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S7 IR spectra of compound Z4 [(E)-2-(3-(4-nitrostyryl)-5-(4-nitrophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S8. IR spectra of compound Z5 [(E)-2-(3-(2-nitrostyryl)-5-(2-nitrophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S9. IR spectra of compound Z6 [(E)-2-(3-(2-chlorostyryl)-5-(2-chlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S10. IR spectra of compound Z7 [(E)-2-(3-(3-hydroxystyryl)-5-(3-hydroxyphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S11. 1H NMR spectra of compound Z7 [(E)-2-(3-(3-hydroxystyryl)-5-(3-hydroxy-phenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S12. 13C NMR spectra of compound Z7 [(E)-2-(3-(3-hydroxystyryl)-5-(3-hydroxy-phenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S13. IR spectra of compound Z8 [(E)-2-(3-(4-hydroxystyryl)-5-(4-hydroxyphenyl)- 4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S14. IR spectra of compound Z9 [(E)-2-(3-(4-bromostyryl)-5-(4-bromophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S15. IR spectra of compound Z10 [(E)-2-(3-(4-methylstyryl)-5-(4-methylphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S16. 1H NMR spectra of compound Z10 [(E)-2-(3-(4-methylstyryl)-5-(4-methyl-phenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S17. IR spectra of compound Z11 [(E)-2-(3-(4-methoxystyryl)-5-(4-methoxyphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S18. 1H NMR spectra of compound Z11 [(E)-2-(3-(4-methoxystyryl)-5-(4-methoxy-phenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S19. IR spectra of compound Z12 [(E)-2-(5-phenyl-3-styryl-4,5-dihydropyrazol-1-yl)-benzo[d]thiazole]. Fig. S20. 1H NMR spectra of compound Z12 [(E)-2-(5-phenyl-3-styryl-4,5-dihydro-pyrazol-1-yl)-benzo[d]thiazole]. Fig. S21. IR spectra of compound Z13 [(E)-2-(3-(4-fluorostyryl)-5-(4-fluorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S22. 1H NMR spectra of compound Z13 [(E)-2-(3-(4-fluorostyryl)-5-(4-fluoro-phenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S23. IR spectra of compound Z14 [(E)-2-(3-(3-methoxystyryl)-5-(3-methoxyphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S24. IR spectra of compound Z15 [(E)-2-(3-(2-methoxystyryl)-5-(2-methoxyphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]-thiazole]. Fig. S25. IR spectra of compound Z16 [(E)-2-(3-(3-bromostyryl)-5-(3-bromophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S26. IR spectra of compound Z17 [(E)-2-(3-(2,3-dichlorostyryl)-5-(2,3-dichlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S27. IR spectra of compound Z18 [(E)-2-(3-(2,6-dichlorostyryl)-5-(2,6-dichlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S28. 1H NMR spectra of compound Z18 [(E)-2-(3-(2,6-dichlorostyryl)-5-(2,6-dichlorophenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole]. Fig. S29. IR spectra of compound Z19 [(E)-2-(3-(2,5-dimethoxystyryl)-5-(2,5-dimethoxyphenyl)-4,5-dihydropyrazol-1-yl) benzo[d]thiazole]. Fig. S30. IR spectra of compound Z20 [(E)-2-(3-(3,4,5-trimethoxystyryl)-5-(3,4,5-trimethoxyphenyl)-4,5-dihydropyrazol-1-yl) benzo[d]thiazole]. Fig. S31. 1H NMR spectra of compound Z20 [(E)-2-(3-(3,4,5-trimethoxystyryl)-5-(3,4,5-trimethoxyphenyl)-4,5-dihydropyrazol-1-yl) benzo[d]thiazole].