cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary documentation for SAEON's field instrument data collected at the Cathedral Peak Weir 07 YSI station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cathedral Peak
Hydrological
Water Quality - Phys-chem YSI
Water Quality
temperature
salinity
conductivity

description: This package contains supporting information for the hydrological data collected at Cathedral Peak's Weir 07 YSI station, as part of the South African Environmental Observation Network's monitoring projects.
How to Recover a Qubit That Has Fallen Into a Black Hole
Creators: name: Chatwin-Davies, Aidan
name: Jermyn, Adam S.
name: Carroll, Sean M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We demonstrate an algorithm for the retrieval of a qubit, encoded in spin angular momentum, that has been dropped into a no-firewall black hole. Retrieval is achieved analogously to quantum teleportation by collecting Hawking radiation and performing measurements on the black hole. Importantly, these methods only require the ability to perform measurements from outside the event horizon.
description: 6 pages v2: modified protocol to discuss total angular momentum, corrected typos, added references v3: updated with referee feedback
Hymenophyllum apteryx M. Kessler & Sundue, Blumea
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum apteryx

description: Hymenophyllum apteryx M.Kessler & Sundue, Blumea 50: 555 (–557), f. 1a–b. 2005.
 Range: —Known only from Bolivia (CO, LP, SC), but likely to be more widespread in the Andes.
 Ecology: —Fairly common; epiphytic in humid forests; 2200–3250 m.
 Notes: —Differs from Hymenophyllum interruptum by the unwinged rachises. This species also tends to have more densely pubescent blades, and shorter, more triangular pinnae and segments. Restricted to high elevations.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on pages 212-213, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis
Creators: name: Troester, Melissa A.
name: Kirk, Erin L.
name: Tan, Ying Siow
name: Zhao, Yong
name: Haslam, Sandra Z.
name: Schwartz, Richard C.
name: Aupperlee, Mark D.
name: Sun, Xuezheng
name: Zhu, Yirong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Premenopausal breast cancer is associated with increased animal fat consumption among normal weight, but not overweight women (Farvid et al., 2014). Our previous findings in obesity-resistant BALB/c mice similarly showed promotion of carcinogen-induced mammary tumorigenesis by a diet high in saturated animal fat (HFD). This effect was specific to pubertal versus adult HFD. This study identifies the effects of HFD during puberty versus adulthood in Trp53-null transplant BALB/c mice and investigates its mechanism of enhancing tumorigenesis. Either pubertal or adult HFD is sufficient to increase incidence of Trp53-null mammary tumors. Puberty-restricted HFD exposure promoted tumor cell proliferation, increased angiogenesis, and increased recruitment of total and M2 macrophages in epithelial tumors. Adult-restricted exposure to HFD similarly increased proliferation, angiogenesis, recruitment of total and M2 macrophages, and additionally reduced apoptosis. Adult HFD also increased incidence of spindle cell carcinomas resembling claudin-low breast cancer, and thus adult HFD in the Trp53-null transplantation system may be a useful model for human claudin low breast cancer. Importantly, these results on Trp53-null and our prior studies on DMBA-induced mammary tumorigenesis demonstrate a pubertal window of susceptibility to the promotional effects of HFD, indicating the potential of early life dietary intervention to reduce breast cancer risk.
Higgs physics beyond the SM: the non-linear EFT approach
Creators: name: Brivio, Ilaria
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Depending on whether electroweak physics beyond the Standard Model is based on a linear or on a non-linear implementation of the electroweak symmetry breaking, a linear or a chiral Effective Lagrangian is more appropriate. In this talk, the main low-energy signals that allow to recognize whether the observed Higgs scalar is a dynamical (composite) particle or rather an elementary one are presented, in a model-independent way. The patterns of effective couplings produced upon the assumption of specific composite Higgs models are also discussed.
description: 8 pages, 1 figure. Proceedings of the talk given at the XXIXth Rencontres de Physique de la Vall\'ee d'Aoste, La Thuile (Italy), March 2015
Hymenophyllum capurroi de la Sota, Darwiniana
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum capurroi

description: Hymenophyllum capurroi de la Sota, Darwiniana 17: 54, f. 5A–C, pl. 1, 2. 1972.
 Range: — Bolivia (CH, SC, TA) to northwestern Argentina.
 Ecology: —Rare; epiphytic in humid forests; 1850–2250 m.
 Notes: —Leaves 3–14 cm long, pinnae simply or apically bifid; blades with long-stalked stellate hairs.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 213, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Mechanism of Skyrmion Attraction in Chiral Magnets near the Ordering Temperatures.
Creators: name: Leonov, Andrey O.
name: Rößler, Ulrich K.
Publisher: name: Basel : MDPI
Year: 2023
Subjects: subject: A-phase
subject: Dzyaloshinskii–Moriya interaction
subject: chiral magnets
subject: conical spiral
subject: precursor effects
subject: skyrmion
subject: 530

description: Isolated chiral skyrmions are investigated within the phenomenological Dzyaloshinskii model near the ordering temperatures of quasi-two-dimensional chiral magnets with Cnv symmetry and three-dimensional cubic helimagnets. In the former case, isolated skyrmions (IS) perfectly blend into the homogeneously magnetized state. The interaction between these particle-like states, being repulsive in a broad low-temperature (LT) range, is found to switch into attraction at high temperatures (HT). This leads to a remarkable confinement effect: near the ordering temperature, skyrmions exist only as bound states. This is a consequence of the coupling between the magnitude and the angular part of the order parameter, which becomes pronounced at HT. The nascent conical state in bulk cubic helimagnets, on the contrary, is shown to shape skyrmion internal structure and to substantiate the attraction between them. Although the attracting skyrmion interaction in this case is explained by the reduction of the total pair energy due to the overlap of skyrmion shells, which are circular domain boundaries with the positive energy density formed with respect to the surrounding host phase, additional magnetization "ripples" at the skyrmion outskirt may lead to attraction also at larger length scales. The present work provides fundamental insights into the mechanism for complex mesophase formation near the ordering temperatures and constitutes a first step to explain the phenomenon of multifarious precursor effects in that temperature region.
Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy: GCB/non-GCB by immunohistochemistry is still a robust and feasible marker
Creators: name: Batlle-López, Ana
name: Grande, Carlos
name: Tzankov, Alexandar
name: Garcia, Juan F.
name: Sáez, Anabel
name: Sánchez, Lydia
name: Young, Ken H.
name: Xu-Monette, Zijun Y.
name: Mazorra, Francisco
name: Visco, Carlo
name: De Villambrosía, Sonia González
name: López, Andrés
name: Mollejo, Manuela
name: Ruiz-Marcellan,
name: Piris, Miguel Angel
name: González-Barca, Eva
name: Montalban, Carlos
name: Cao, Xin
name: Richards,
name: Conde, Eulogio
name: Montes-Moreno, Santiago
name: Hsi,
name: Malatxeberria, Sefora
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Diffuse large B cell lymphoma (DLBCL) is a heterogeneous group of aggressive lymphomas that can be classified into three molecular subtypes by gene expression profiling (GEP): GCB, ABC and unclassified. Immunohistochemistry-based cell of origin (COO) classification, as a surrogate for GEP, using three available immunohistochemical algorithms was evaluated in TMA-arranged tissue samples from 297 patients with de novo DLBCL treated by chemoimmunotherapy (R-CHOP and R-CHOP-like regimens). Additionally, the prognostic impacts of MYC, BCL2, IRF4 and BCL6 abnormalities detected by FISH, the relationship between the immunohistochemical COO classification and the immunohistochemical expression of MYC, BCL2 and pSTAT3 proteins and clinical data were evaluated.
Leucadendron pubescens at site 3219AC/12
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Leucadendron pubescens

description: This is a scanned copy of a document recording the Leucadendron pubescens at site 3219AC/12. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
Hymenophyllum hemidimorphum R. C. Moran & B. Øllg., Nordic J. Bot.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum hemidimorphum

description: Hymenophyllum hemidimorphum R.C.Moran & B.Øllg., Nordic J. Bot. 15: 183, f. 4. 1995.
 Range: — Costa Rica; Colombia; Ecuador; Bolivia (CO).
 Ecology: —Rare, known in Bolivia from two collections; epiphytic in very wet montane forests; 1950–2000 m.
 Notes: —Unique in having by hemidimorphic leaves, i.e., blades with proximal fertile and distal sterile parts of different morphology. It further differs from H. elegans by rachises, costae, and margins with simple hairs (vs. forked or stellate), and by larger size (leaves to 36 cm long vs. 20 cm long).
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 213, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Optimal Control of Overdamped Systems
Creators: name: Zulkowski, Patrick R.
name: DeWeese, Michael R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Nonequilibrium physics encompasses a broad range of natural and synthetic small-scale systems. Optimizing transitions of such systems will be crucial for the development of nanoscale technologies and may reveal the physical principles underlying biological processes at the molecular level. Recent work has demonstrated that when a thermodynamic system is driven away from equilibrium then the space of controllable parameters has a Riemannian geometry induced by a generalized inverse diffusion tensor. We derive a simple, compact expression for the inverse diffusion tensor that depends solely on equilibrium information for a broad class of potentials. We use this formula to compute the minimal dissipation for two model systems relevant to small-scale information processing and biological molecular motors. In the first model, we optimally erase a single classical bit of information modelled by an overdamped particle in a smooth double-well potential. In the second model, we find the minimal dissipation of a simple molecular motor model coupled to an optical trap. In both models, we find that the minimal dissipation for the optimal protocol is inversely proportional to protocol duration, as expected, though the dissipation for the erasure model takes a different form than what we found previously for a similar system.
Transverse spin and spin-orbit coupling in silicon waveguides
Creators: name: Espinosa-Soria, Alba
name: Martinez, Alejandro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Evanescent and tightly confined propagating waves exhibit a remarkable transverse spin density since the longitudinal component of the electric field is not negligible. In this work, we obtain via numerical simulations the electric field components of the fundamental guided modes of two waveguides typically used in silicon photonics: the strip and the slot waveguide. We obtain the relation between transverse and longitudinal field components, the transverse spin densities and other important parameters, such as the longitudinal component of the so-called Belinfante spin momentum density. By asymmetrically placing a circularly-polarized point-like dipole source in regions showing local circular polarization, the guided mode is excited unidirectionally via spin-orbit coupling. In contrast to metal plates supporting surface plasmons, the multimode behavior of silicon waveguides results in different spin-orbit coupling properties for each guided mode. Our results may find application in silicon photonic devices, integrated quantum optics and polarization manipulation at the nanoscale.
description: 11 pages, 5 figures, updated version
Supplementary documentation for SAEON's field instrument data collected at the Jonkershoek Biesievlei station
Creators: name: South African Environmental Observation Network (SAEON) Fynbos Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Jonkershoek
Hydrological
Weir
Water level
water temperature

description: This package contains supporting information for the hydrological data collected at Jonkershoek's Biesievlei station, as part of the South African Environmental Observation Network's monitoring projects.
Hymenophyllum latisorum M. Kessler & A. R. Sm., Blumea
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum latisorum

description: Hymenophyllum latisorum M.Kessler & A.R.Sm., Blumea 50: 558 (556–559), f. 1e–f. 2005.
 Range: —Known only from Bolivia (CO, SC), but likely to be more widespread in the Andes.
 Ecology: —Rare; epiphytic in humid forests; 2000–3000 m.
 Notes: —Differs from Hymenophyllum microcarpum by having broader than long, hairy involucres, wavy rachis wings, and from H. valvatum by broad, hairy involucres and flat segments (vs. undulate).
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 214, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Supplementary documentation for SAEON's field instrument data collected at the Cape Agulhas Rhenosterkop pan station
Creators: name: South African Environmental Observation Network (SAEON) Fynbos Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cape Agulhas
Hydrological
Solinst depth, temperature and conductivity logger
water level
water temperature

description: This package contains supporting information for the hydrological data collected at Cape Agulhas's Rhenosterkop pan station, as part of the South African Environmental Observation Network's monitoring projects.
The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer
Creators: name: Zhou, Chunxiao
name: Bae-Jump, Victoria L.
name: Schuler, Kevin M.
name: Suri, Anuj
name: Zhong, Yan
name: Han, Xiaoyun
name: Gehrig, Paola A.
name: Sheng, Xiugui
name: Jones, Hannah M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Our objective was to evaluate the effect of the COX-2 inhibitor, celecoxib, on (1) proliferation and apoptosis in human ovarian cancer cell lines and primary cultures of ovarian cancer cells, and (2) inhibition of tumor growth in a genetically engineered mouse model of serous ovarian cancer under obese and non-obese conditions. Celecoxib inhibited cell proliferation in three ovarian cancer cell lines and five primary cultures of human ovarian cancer after 72 hours of exposure. Treatment with celecoxib resulted in G1 cell cycle arrest, induction of apoptosis, inhibition of cellular adhesion and invasion and reduction of expression of hTERT mRNA and COX-2 protein in all of the ovarian cancer cell lines. In the KpB mice fed a high fat diet (obese) and treated with celecoxib, tumor weight decreased by 66% when compared with control animals. Among KpB mice fed a low fat diet (non-obese), tumor weight decreased by 46% after treatment with celecoxib. In the ovarian tumors from obese and non-obese KpB mice, treatment with celecoxib as compared to control resulted in decreased proliferation, increased apoptosis and reduced COX-2 and MMP9 protein expression, as assessed by immunohistochemistry. Celecoxib strongly decreased the serum level of VEGF and blood vessel density in the tumors from the KpB ovarian cancer mouse model under obese and non-obese conditions. This work suggests that celecoxib may be a novel chemotherapeutic agent for ovarian cancer prevention and treatment and be potentially beneficial in both obese and non-obese women.
Hymenophyllum platylobum Bosch, Ned. Kruidk. Arch.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum platylobum

description: Hymenophyllum platylobum Bosch, Ned. Kruidk. Arch. 5: 189. 1863.
 Range: —Andes from Venezuela to Bolivia (CO, LP).
 Ecology: —Fairly common; epiphytic in humid forests; 1300–1900 m.
 Notes: —Differs from H. microcarpum by thicker, mostly forked hairs on segment margins (vs. always simple), broader, hairy involucres, and shorter, more spreading pinnae (vs. attenuate and bending apically). Quite variable in segment width.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 214, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Aharonov-Bohm interferometer based on n-p junction in graphene nanoribbons
Creators: name: Mreńca-Kolasińska, Alina
name: Heun, Stefan
name: Szafran, Bartłomiej
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate that the phenomenon of current confinement along graphene n-p junctions at high magnetic fields can be used to form an Aharonov-Bohm interferometer. The interference system exploits a closed n-p junction that can be induced by a floating gate within the sample, and coupling of the junction currents with the edge currents in the quantum Hall regime. Operation of the device requires current splitting at the edge and the n-p junction contacts which is found for armchair ribbons at low Fermi energy.
description: 10 pages, 7 figures
The functions and clinical applications of tumor-derived exosomes
Creators: name: Zheng, Shu
name: Xu, Fei
name: Chen, Ting
name: Shao, Yingkuan
name: Chen, Xuewen
name: Shen, Yanwei
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Exosomes are extracellular vesicles with diameters ranging from 30 to 150 nm. They can be secreted by all cell types and transfer information in the form of their contents, which include proteins, lipids and nucleic acids, to other cells throughout the body. They have roles in normal physiological processes as well as in disease development. Here, we review recent findings regarding tumor-derived exosomes, including methods for their extraction and preservation. We also describe the actions of exosomes in tumorigenesis. The exosomal antigen-presenting effect during antitumor immune responses and its suppressive function in immune tolerance are discussed. Finally, we describe the potential application of exosomes to cancer therapy and liquid biopsy.
Supplementary documentation for SAEON's field instrument data collected at the Cathedral Peak Weir 09 station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cathedral Peak
Hydrological
Pressure transducer CS
Streamflow
Water temperature

description: This package contains supporting information for the hydrological data collected at Cathedral Peak's Weir 09 station, as part of the South African Environmental Observation Network's monitoring projects.
Protea nitida in the Cederberg Wilderness Area, site 3219AC/16
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Protea nitida
Cederberg
Cederberg Wilderness Area

description: This is a scanned copy of a document, including maps and photographs, on Protea nitida in the Cederberg Wilderness Area, site 3219AC/16. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape.   SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
Test of quantum chemistry in vibrationally-hot hydrogen molecules
Creators: name: Niu, M. L.
name: Salumbides, E. J.
name: Ubachs, W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Precision measurements are performed on highly excited vibrational quantum states of molecular hydrogen. The $v=12, J=0-3$ rovibrational levels of H$_2$ ($X^1Σ_g^+$), lying only $2000$ cm$^{-1}$ below the first dissociation limit, were populated by photodissociation of H$_2$S and their level energies were accurately determined by two-photon Doppler-free spectroscopy. A comparison between the experimental results on $v=12$ level energies with the best \textit{ab initio} calculations shows good agreement, where the present experimental accuracy of $3.5 \times10^{-3}$ cm$^{-1}$ is more precise than theory, hence providing a gateway to further test theoretical advances in this benchmark quantum system.
description: 5 pages, 4 figures, and 2 tables
Brane polarization is no cure for tachyons
Creators: name: Bena, Iosif
name: Kuperstein, Stanislav
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Anti-M2 and anti-D3 branes placed in regions with charges dissolved in fluxes have a tachyon in their near-horizon region, which causes these branes to repel each other. If the branes are on the Coulomb branch this tachyon gives rise to a runaway behavior, but when the branes are polarized into five-branes this tachyon only appears to lower the energy of the polarized branes, without affecting its stability. We analyze brane polarization in the presence of a brane-brane-repelling tachyon and show that when the branes are polarized along the direction of the tachyon the polarized shell is unstable. This implies that tachyons cannot be cured by brane polarization and indicates that, at least in a certain regime of parameters, anti-D3 branes polarized into NS5 branes at the bottom of the Klebanov-Strassler solution have an instability.
description: 10 pages, 1 figure, JHEP style
Hymenophyllum subrigidum Christ, Bull. Herb. Boissier
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum subrigidum

description: Hymenophyllum aff. subrigidum Christ, Bull. Herb. Boissier, sér. 2, 5: 260. 1905.
 Range: —Known in Bolivia (CO), from a single, sterile collection (Kessler 7080, LPB, UC).
 Ecology: —Rare; epiphytic in humid forests; 2350 m.
 Notes: —Differs from Hymenophyllum subrigidum Christ, from Costa Rica to Venezuela, by stalked, forked marginal hairs (vs. simple or basally forked). We include this record here to call attention to this potentially undescribed species.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 216, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Causal non-locality can arise from constrained replication
Creators: name: van Hateren, J. H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Biological Physics (physics.bio-ph)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: The fundamental theories of physics are local theories, depending on local interactions of local variables. It is not clear if and how strictly local theories can produce non-local variables that have causal effectiveness. Yet, non-local effectiveness appears to exist, such as in the form of memory (non-locality through time) and causally effective spatial structures (non-locality through space). Here it is shown, by construction, how such non-locality can be produced from elementary components: non-isolated systems, multiplicative noise, self-replication, and elimination. A theory is derived that explains how causal non-locality can arise from strictly local interactions.
description: Revision, 5 pages
The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumorigenic effects in ovarian cancer
Creators: name: Stine, Jessica E.
name: Sheng, Xiugui
name: Gilliam, Timothy P.
name: Schointuch, Monica N.
name: Han, Xiaoyun
name: Gehrig, Paola A.
name: Guo, Hui
name: Bae-Jump, Victoria L.
name: Zhou, Chunxiao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Ovarian cancer is the 5th leading cause of cancer death among women in the United States. The mevalonate pathway is thought to be a potential oncogenic pathway in the pathogenesis of ovarian cancer. Simvastatin, a 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR) inhibitor, is a widely used drug for inhibiting the synthesis of cholesterol and may also have anti-tumorigenic activity. Our goal was to evaluate the effects of simvastatin on ovarian cancer cell lines, primary cultures of ovarian cancer cells and in an orthotopic ovarian cancer mouse model. Simvastatin significantly inhibited cellular proliferation, induced cell cycle G1 arrest and apoptosis, and caused cellular stress via reduction in the enzymatic activity of HMGCR and inhibition of the MAPK and mTOR pathways in ovarian cancer cells. Furthermore, simvastatin induced DNA damage and reduced cell adhesion and invasion. Simvastatin also exerted anti-proliferative effects on primary cell cultures of ovarian cancer. Treatment with simvastatin in an orthotopic mouse model reduced ovarian tumor growth, coincident with decreased Ki-67, HMGCR, phosphorylated-Akt and phosphorylated-p42/44 protein expression. Our findings demonstrate that simvastatin may have therapeutic benefit for ovarian cancer treatment and be worthy of further exploration in clinical trials.
Hymenophyllum trapezoidale Liebm., Kongel. Danske Vidensk. Selsk. Skr., Nat. Math. Afd.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum trapezoidale

description: Hymenophyllum trapezoidale Liebm., Kongel. Danske Vidensk. Selsk. Skr., Nat. Math. Afd., ser. 5, 1: 293. 1849.
 Range: — Mexico and Guatemala; Colombia; Suriname; Bolivia (CO, LP, SC).
 Ecology: —Uncommon; epiphytic in humid forests; 2300–3100 m.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 217, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Toward targeted therapy in chemotherapy-resistant pancreatic cancer with a smart triptolide nanomedicine
Creators: name: Xu, Wei
name: Wang, Cheng
name: Yin, Jiaqi
name: Xu, Xuelian
name: Lu, Aiping
name: Cong, Mengyi
name: Zhuang, Bo
name: Liu, Biao
name: Li, Hongxia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Chemoresistance is the major impediment for treating pancreatic cancer. Herb-derived compound triptolide (TP) can inhibit proliferation of chemo-resistant pancreatic cancer (CPC) cell lines through multiple mechanisms, which exhibited superior anticancer efficacy compared with gemcitabine. However, toxicity due to non-specific exposure to healthy tissues hindered its clinical translation. Herein we successfully achieved targeting CPC cells and avoiding exposure to healthy tissues for TP by nucleolin-specific aptamer (AS1411) mediated polymeric nanocarrier. We conjugated AS1411 aptamer to carboxy terminated poly(ethylene glycol)–block–poly(d, l-lactide) (HOOC-PEG-PDLLA), then prepared AS1411-PEG-PDLLA micelle loading TP (AS-PPT) through solid dispersion technique. AS-PPT showed more antitumor activity than TP and equivalent specific binding ability with gemcitabine-resistant human pancreatic cancer cell (MIA PaCa-2) to AS1411 aptamer in vitro. Furthermore, we studied the distribution of AS-PPT (Cy3-labed TP) at tissue and cellular levels using biophotonic imaging technology. The results showed AS1411 facilitated TP selectively accumulating in tumor tissues and targeting CPC cells. The lifetime of the MIA PaCa-2 cell-bearing mice administrated with AS-PPT was efficiently prolonged than that of the mice subjected to the clinical anticancer drug Gemzar®in vivo. Such work provides a new strategy for overcoming the drug resistance of pancreatic cancer.
Hymenophyllum verecundum C. V. Morton, Contr. U. S. Natl. Herb.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Hymenophyllum
Hymenophyllum verecundum

description: Hymenophyllum verecundum C.V.Morton, Contr. U.S. Natl. Herb. 29: 183. 1947.
 Range: — Colombia to Bolivia (CO, LP).
 Ecology: —Fairly common; pendent epiphyte in humid forests, less commonly on wet road banks; 1700–2900 m.
 Notes: —Differs from Hymenophyllum pyramidatum by shorter pinnae 6–20 mm long, with fewer segments (3–6(8) pairs), and oblong to broadly triangular, obtuse to subacute pinnae. Usually at higher elevations than H. pyramidatum.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 217, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
The effect of Coulomb interactions on nonlinear thermovoltage and thermocurrent in quantum dots
Creators: name: Zimbovskaya, Natalya A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In the present work, we theoretically study the nonlinear regime of charge transport through a quantum dot coupled to the source and drain reservoirs. The investigation is carried out using a nonequilibrium Green's functions formalism beyond the Hartree-Fock approximation. Employed approximations for the relevant Green's functions allow to trace a transition from Coulomb blockade regime to Kondo regime in the thermoelectric transport. Effects arising when electrons move in response to thermal gradient applied across the system are discussed, including experimentally observed thermovoltage zeros.
description: 9 pages, 10 figures
Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach
Creators: name: Liu, Song
name: Sucheston-Campbell, Lara
name: Olshan, Andrew F.
name: Palmer, Julie R.
name: Hu, Qiang
name: Liu, Qian
name: Bandera, Elisa V.
name: Zhu, Qianqian
name: Bensen, Jeannette T.
name: Ambrosone, Christine B.
name: Yao, Song
name: Shepherd, Lori
name: Haiman, Christopher A.
name: Lunetta, Kathryn L.
name: Rosenberg, Lynn
name: Haddad, Stephen A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Leveraging population-distinct linkage equilibrium (LD) patterns, trans-ethnic follow-up of variants discovered from genome-wide association studies (GWAS) has proved to be useful in facilitating the identification of bona fide causal variants. We previously developed the preferential LD approach, a novel method that successfully identified causal variants driving the GWAS signals within European-descent populations even when the causal variants were only weakly linked with the GWAS-discovered variants. To evaluate the performance of our approach in a trans-ethnic setting, we applied it to follow up breast cancer GWAS hits identified mostly from populations of European ancestry in African Americans (AA). We evaluated 74 breast cancer GWAS variants in 8,315 AA women from the African American Breast Cancer Epidemiology and Risk (AMBER) consortium. Only 27% of them were associated with breast cancer risk at significance level α=0.05, suggesting race-specificity of the identified breast cancer risk loci. We followed up on those replicated GWAS hits in the AMBER consortium utilizing the preferential LD approach, to search for causal variants or better breast cancer markers from the 1000 Genomes variant catalog. Our approach identified stronger breast cancer markers for 80% of the GWAS hits with at least nominal breast cancer association, and in 81% of these cases, the marker identified was among the top 10 of all 1000 Genomes variants in the corresponding locus. The results support trans-ethnic application of the preferential LD approach in search for candidate causal variants, and may have implications for future genetic research of breast cancer in AA women.
On Axionic Field Ranges, Loopholes and the Weak Gravity Conjecture
Creators: name: Brown, Jon
name: Cottrell, William
name: Shiu, Gary
name: Soler, Pablo
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this short note we clarify some aspects of the impact that the Weak Gravity Conjecture has on models of (generalized) natural inflation. We address in particular certain technical and conceptual concerns recently raised regarding the stringent constraints and conclusions found in our previous work (arXiv:1503.04783). We also point out the difficulties faced by attempts to evade these constraints. These new considerations improve the understanding of the quantum gravity constraints we found and further support the conclusion that it remains challenging for axions to drive natural inflation.
description: 14 pages
A seven-gene signature predicts overall survival of patients with colorectal cancer
Creators: name: Bai, Rui
name: Chen, Huarong
name: Qian, Yun
name: Sun, Xiaoqiang
name: Ge, Weiting
name: Zheng, Shu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Colorectal cancer (CRC) is a major cause of global cancer mortality. Gene expression profiles can help predict prognosis of patients with CRC. In most of previous studies, disease recurrence was analyzed as the survival endpoint. Thus we aim to build a robust gene signature for prediction of overall survival (OS) in patients with CRC. Fresh frozen CRC tissues from 64 patients were analyzed using Affymetrix HG-U133plus 2.0 gene arrays. By performing univariate survival analysis, 6487 genes were found to be associated with the OS in our cohort. KEGG analysis revealed that these genes were mainly involved in pathways such as endocytosis, axon guidance, spliceosome, Wnt signalling and ubiquitin mediated proteolysis. A seven-gene signature was further selected by a robust likelihood-based survival modelling approach. The prognostic model of seven-gene signature (NHLRC3, ZDHHC21, PRR14L, CCBL1, PTPRB, PNPO, and PPIP5K2) was constructed and weighted by regression coefficient, which divided patients into high- and low-risk groups. The OS for patients in high-risk group was significantly poorer compared with patients in low-risk group. Moreover, all seven genes were found to be differentially expressed in CRC tissues as compared with adjacent normal tissues, indicating their potential role in CRC initiation and progression. This seven-gene signature was further validated as an independent prognostic marker for OS prediction in patients with CRC in other two independent cohorts. In short, we developed a robust seven-gene signature that can predict the OS for CRC patients, providing new insights into identification of CRC patients with high risk of mortality.
The Optimal Temporal Decay Estimates for the Fractional Power Dissipative Equation in Negative Besov Spaces
Creators: name: Zhao, Jihong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this paper, we first generalize a new energy approach, developed by Y. Guo and Y. Wang \cite{GW12}, in the framework of homogeneous Besov spaces for proving the optimal temporal decay rates of solutions to the fractional power dissipative equation, then we apply this approach to the supercritical and critical quasi-geostrophic equation and the critical Keller-Segel system. We show that the negative Besov norm of solutions is preserved along time evolution, and obtain the optimal temporal decay rates of the spatial derivatives of solutions by the Fourier splitting approach and the interpolation techniques.
description: 23 pages. arXiv admin note: text overlap with arXiv:1508.02023
Autologous reconstitution of human cancer and immune system in vivo
Creators: name: Hayes, D. Neil
name: Chung, Christine H.
name: Walter, Vonn
name: Sen, Rupashree
name: Fu, Juan
name: Pardoll, Drew
name: Masica, David L.
name: Karchin, Rachel
name: Kim, Young J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Correlative studies from checkpoint inhibitor trials have indicated that better understanding of human leukocytic trafficking into the human tumor microenvironment can expedite the translation of future immune-oncologic agents. In order to directly characterize signaling pathways that can regulate human leukocytic trafficking into the tumor, we have developed a completely autologous xenotransplantation method to reconstitute the human tumor immune microenvironment in vivo. We were able to genetically mark the engrafted CD34+ bone marrow cells as well as the tumor cells, and follow the endogenous leukocytic infiltration into the autologous tumor. To investigate human tumor intrinsic factors that can potentially regulate the immune cells in our system, we silenced STAT3 signaling in the tumor compartment. As expected, STAT3 signaling suppression in the tumor compartment in these autologously reconstituted humanized mice showed increased tumor infiltrating lymphocytes and reduction of arginase-1 in the stroma, which were associated with slower tumor growth rate. We also used this novel system to characterize human myeloid suppressor cells as well as to screen novel agents that can alter endogenous leukocytic infiltration into the tumor. Taken together, we present a valuable method to study individualized human tumor microenvironments in vivo without confounding allogeneic responses.
Functional dependence of axial anomaly via mesonic fluctuations in the three flavor linear sigma model
Creators: name: Fejos, G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Temperature dependence of the $U_A(1)$ anomaly is investigated by taking into account mesonic fluctuations in the $U(3)\times U(3)$ linear sigma model. A field dependent anomaly coefficient function of the effective potential is calculated within the finite temperature functional renormalization group approach. The applied approximation scheme is a generalization of the chiral invariant expansion technique developed in [G. Fejos, Phys. Rev. D 90, 096011 (2014)]. We provide an analytic expression and also numerical evidence that depending on the relationship between the two quartic couplings, mesonic fluctuations can either strengthen of weaken the anomaly as a function of the temperature. The role of the six-point invariant of the $U(3)\times U(3)$ group, and therefore the stability of the chiral expansion is also discussed in detail.
description: 10 pages, 3 figures, minor changes, Published in Phys. Rev. D
Polyphlebium herzogii A. R. Sm. & M. Kessler 2017, comb. nov.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Polyphlebium
Polyphlebium herzogii

description: Polyphlebium herzogii (Rosenst.) A.R.Sm. & M.Kessler, comb. nov.
 Basionym: Trichomanes herzogii Rosenst., Meded. Rijks-Herb. 19: 5. 1913.
 Range: —Eastern Andes from Ecuador to Bolivia (CO, LP, TA).
 Ecology: —Fairly common; epiphytic in humid forests; 550–1500(–2100) m.
 Notes: —Pinnules narrower and more parallel than in Polyphlebium diaphanum.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 219, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
title: Albert Camus’ reading of Søren Kierkegaard’s Fear and Trembling
Creators: name: Abel, Johannes
Publisher: name: Albert Camus Society
Year: 2018

description: The paper argues that a comparison of the normative concepts of a good life in Camus and Kierkegaard should be first and foremost a structural comparison, as Camus' interpretation of Fear and Trembling as both a discovery of what Camus himself calls the absurd and as an inconsequent transition from the absurd to the religious disregards the Christian paradigm the work of Kierkegaard is embedded in.
Trichomanes accedens C. Presl, Epimel. Bot.
Creators: name: Kessler, Michael
name: Smith, Alan R.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Trichomanes
Trichomanes accedens

description: Trichomanes accedens C.Presl, Epimel. Bot. 14. 1851.
 Range: — Trinidad; Guianas across Amazonia to Colombia, central Brazil, and Bolivia (LP, PA, SC).
 Ecology: —Rare; terrestrial, on rocks, and on fallen tree trunks, in humid forests; to 900 (–1200) m.
 Notes: —The diagnostic petiole wings are very narrow and can be difficult to see in dried specimens, but the petioles often appear slightly flattened. Rhizomes are erect to ascending, and the leaves clustered; proximal pinnae are directed downwards.
description: Published as part of Kessler, Michael & Smith, Alan R., 2017, Prodromus of a fern flora for Bolivia. X. Hymenophyllaceae, pp. 201-226 in Phytotaxa 328 (3) on page 220, DOI: 10.11646/phytotaxa.328.3.1, http://zenodo.org/record/13722868
Supplementary documentation for SAEON's field instrument data collected at the Cathedral Peak CAT9 #3 station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Cathedral Peak
Hydrological
Soil Diviner tube
Soil water content

description: This package contains supporting information for the hydrological data collected at Cathedral Peak's CAT9 #3 station, as part of the South African Environmental Observation Network's monitoring projects.
Differential response to exercise in claudin-low breast cancer
Creators: name: Bowie, Michelle
name: Glass, Oliver K.
name: Choudhury, K. Roy
name: Zhang, Zoe
name: Usary, Jerry
name: Jones, Lee W.
name: Dewhirst, Mark W.
name: Williams, Christina
name: Liu, Xioajing
name: Fuller, Julie
name: Darr, David
name: Locasale, Jason W.
name: Boss, Keara
name: Seewaldt, Victoria
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Exposure to exercise following a breast cancer diagnosis is associated with reductions in the risk of recurrence. However, it is not known whether breast cancers within the same molecular-intrinsic subtype respond differently to exercise. Syngeneic mouse models of claudin-low breast cancer (i.e., EO771, 4TO7, and C3(1)SV40Tag-p16-luc) were allocated to a uniform endurance exercise treatment dose (forced treadmill exercise) or sham-exercise (stationary treadmill). Compared to sham-controls, endurance exercise treatment differentially affected tumor growth rate: 1- slowed (EO771), 2- accelerated (C3(1)SV40Tag-p16-luc), or 3- was not affected (4TO7). Differential sensitivity of the three tumor lines to exercise was paralleled by effects on intratumoral Ki-67, Hif1-α, and metabolic programming. Inhibition of Hif1-α synthesis by the cardiac glycoside, digoxin, completely abrogated exercise-accelerated tumor growth in C3(1)SV40Tag-p16-luc. These results suggest that intratumoral Hif1-α expression is an important determinant of claudin-low breast cancer adaptation to exercise treatment.