cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Unravelling the role of multimolecular G-quadruplexes in promoting aggregation in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Creators: name: Raguseo, Federica
Publisher: name: Imperial College London
Year: 2023

description: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are just two of the neurodegenerative diseases characterised by the presence of pathological aggregates composed of proteins and RNA. The mechanism of aggregate formation has historically defined proteins as nucleation triggers, but recent studies have highlighted the fundamental role of nucleic acids in the aggregation events. In particular, 40% of familiar cases in ALS/FTD have been correlated to mutations in the hexanucleotide repeat (GGGGCC)n, which in its RNA form has been identified within the aggregates. This work aimed to investigate the aggregation properties of (GGGGCC)n and unveil the underpinning molecular mechanism in the context of the ALS/FTD diseases. In these studies, I firstly showed that (GGGGCC)n DNA oligonucleotides can in the absence of proteins, and that aggregation is facilitated by higher RNA concentrations and number of repeats. I then demonstrated that aggregation is mediated by the formation of multimolecular G-quadruplexes (mG4s) and proceeded to disassemble the aggregates by employing G4-specific tools or altering the molecularity of the system via mutation analysis and antisense treatment. I validated the biological relevance of my findings by demonstrating the ability of RNA (GGGGCC)n to form mG4-rich aggregates similar to its DNA equivalents and by examining the interactions of these strands with TDP-43, a protein relevant to ALS/FTD. Furthermore, I confirmed the potential therapeutical relevance of the studies by demonstrating the ability of a G4-selective fluorescent probe to penetrate C9orf72 mutant human motor neurons derived from ALS patients, which revealed clear fluorescent signal in putative condensates. My findings strongly suggest that (GGGGCC)n can form protein-free condensates sustained by multimolecular G-quadruplexes, highlighting their potential relevance as therapeutic targets for C9orf72 mutation-related ALS and FTD.
title: Transnationale queere Solidarität als „burden of the fittest“? Zur Problematik einer Einpassung von LGBTIQ*-Rechten in die Logik von Entwicklungszusammenarbeit
Creators: name: Klapeer, Christine M.
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: Intersektionalität
subject: Postkolonialismus
subject: Queer
subject: Solidarität
subject: ddc:300

description: Auf der Basis einer produktiven Zusammenführung von Erkenntnissen aus dem Bereich der postkolonialen und ‚radikalen‘ Entwicklungsforschung und queeren Auseinandersetzungen mit homonationalistischen Implikationen globaler LGBTIQ*-Politiken diskutiert dieser Beitrag das Spannungsverhältnis zwischen Entwicklungszusammenarbeit und transnationaler queerer Solidarität. Es wird gezeigt, inwiefern Solidarität vor dem Hintergrund einer problematischen Aktualisierung modernisierungstheoretischer und developmentalistischer Annahmen im Zuge LGBTIQ*-inklusiver bzw. SOGI-sensibler Entwicklungsagenden vor allem als eine Verantwortung ‚der Entwickelten‘ bzw. mit Gayatri Chakravorty Spivak gesprochen, als „burden of the fittest“, geframt wird. In diesem Zusammenhang nimmt der Beitrag auf der Basis postkolonialer Entwicklungskritiken die selbstaffirmativen Implikationen von entwicklungspolitischen Artikulationen transnationaler queerer Solidarität in den Blick und untersucht, inwieweit diese als eine Form der okzidentalistischen Selbstvergewisserung interpretiert werden können. In einem letzten Teil wird problematisiert, inwiefern eine Viktimisierung von LGBTIQ*s im Globalen Süden bzw. insgesamt eine sogenannte Spektakularisierung von Gewalt gegen LGBTIQ*s in den sogenannten Partnerländern als zentraler diskursiver Bedingungsrahmen für transnationale queere Solidarität fungiert.
title: Etwas stimmte nicht. Narrative Allianzen und retrospektive Zeug*innenschaft
Creators: name: Moisi, Laura
Publisher: name: Humboldt-Universität zu Berlin
Year: 2019
Subjects: subject: Allianzen
subject: Sexuelle Übergriffe
subject: Solidarität
subject: Widerstand
subject: ddc:300

description: In diesem Beitrag geht es um die Frage, wie literarische, filmische und autobiografische Schilderungen von unerwünschten Berührungen und sexuellen Übergriffen zur Grundlage von politischen Allianzen werden. Ausgehend von kulturwissenschaftlichen Perspektiven auf Affekt und Geschlecht, insbesondere mit Blick auf Sara Ahmeds queer-feministische Arbeiten, beschäftigt sich der Beitrag mit gegenwärtigen Neuaushandlungen von feministischer Solidarität. Dabei soll ein Blick auf Formen feministischer Solidarität geworfen werden, die sich weniger an der Überwindung von Gefühlen der Ohnmacht orientieren und mehr an einer narrativen Aufarbeitung von Gewalterfahrungen. Vergangenheit und Gegenwart, persönliche Schicksale und Kulturgeschichte, verschränken sich dabei auf produktive Weise. Bezugnehmend auf gegenwärtige kulturelle Aufarbeitungen von sexualisierter Gewalt in sozialen Medien, Essays und Erzählbänden, geht es um die Frage, wie fiktive und autobiografische Erzählpraktiken Vorstellungen von Handlungsmacht und Passivität, von Dominanz und Opferstatus herausfordern. Dabei wird ein Blick auf narrative Allianzen als feministische Solidaritätsform skizziert, die affektive Verweigerungen und Widerstände sichtbar macht.
From multiple integrals to Fredholm determinants
Creators: name: Seel, Alexander
name: Göhmann, Frank
name: Klümper, Andreas
Publisher: name: arXiv
Year: 2007
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a multiple integral representation for the finite temperature density-density correlation functions of the one-dimensional Bose gas with delta function interaction in the limits of infinite and vanishing repulsion. In the former case a known Fredholm determinant is recovered. In the latter case a similar expression appears with permanents replacing determinants.
description: 11 pages, section on the free Boson limit added
Scale-invariance as the cause of the superconducting dome in the cuprates
Creators: name: Leong, Zhidong
name: Limtragool, Kridsanaphong
name: Setty, Chandan
name: Phillips, Philip W.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Recent photoemission spectroscopy measurements (T. J. Reber et al., arXiv:1509.01611) of cuprate superconductors have inferred that the self-energy exhibits critical scaling over an extended doping regime, thereby calling into question the conventional wisdom that critical scaling exists only at isolated points. In particular, this new state of matter, dubbed a power-law liquid, has a self-energy whose imaginary part scales as $Σ^{\prime\prime}\sim(ω^{2}+π^{2}T^{2})^α$, with $α=1$ in the overdoped Fermi-liquid state and $α\leq0.5$ in the optimal to underdoped regime. Previously, we showed that this self-energy can arise from interactions between electrons and unparticles, a scale-invariant sector that naturally emerges from strong correlations. Here, taking the self-energy as a given, we first reconstruct the real part of the self-energy. We find that the resultant quasiparticle weight vanishes for any doping level less than optimal, implying an absence of particle-like excitations in the underdoped regime. Consequently, the Fermi velocity vanishes and the effective mass diverges for $α\leq\frac{1}{2}$, in agreement with earlier experimental observations. We then use the self-energy to reconstruct the spectral function and compute the superconducting $T_c$ within the BCS formalism. We find that the $T_c$ has a dome-like structure, implying that broad scale invariance manifested in the form of a power-law liquid is the likely cause of the superconducting dome in the cuprates.
description: 9 pages, 6 figures. to be published in Phys. Rev. B
Regularization dependence of the Higgs mass triviality bound
Creators: name: Heller, Urs M.
name: Klomfass, Markus
name: Neuberger, Herbert
name: Vranas, Pavlos
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We calculate the triviality bound on the Higgs mass in scalar field theory models whose global symmetry group $SU(2)_L \times SU(2)_{\rm custodial} \approx O(4)$ has been replaced by $O(N)$ and $N$ has been taken to infinity. Limits on observable cutoff effects at four percent in several regularized models with tunable couplings in the bare action yield triviality bounds displaying a large degree of universality. Extrapolating from $N=\infty$ to $N=4$ we conservatively estimate that a Higgs particle with mass up to $0.750~TeV$ and width up to $0.290~TeV$ is realizable without large cutoff effects, indicating that strong scalar self interactions in the standard model are not ruled out. We also present preliminary numerical results of the physical $N=4$ case for the $F_4$ lattice that are in agreement with the large $N$ expectations. Note: The full ps file is also available via anonymous ftp to ftp.scri.fsu.edu. To get the ps file, ftp to this address and use for username "anonymous" and for password your name. The file is in the directory pub/vranas (to go to that directory type: cd pub/vranas) and is called lat92_proc.ps (to get it type: get lat92_proc.ps)
description: 5 pages with 5 ps figures included. LaTex file. Contribution to the LAT92 proceedings. Preprint, FSU-SCRI-92-150, RU-92-43
Additional file 3 of Treatment of the lung injury of drowning: a systematic review
Creators: name: Thom, Ogilvie
name: Roberts, Kym
name: Devine, Susan
name: Leggat, Peter A.
name: Franklin, Richard C.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 3. Summary Table of included studies.
Large Volume Axionic Swiss-Cheese Inflation
Creators: name: Misra, Aalok
name: Shukla, Pramod
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Continuing with the ideas of (section 4 of) [1], after inclusion of perturbative and non-perturbative alpha' corrections to the Kaehler potential and (D1- and D3-) instanton generated superpotential, we show the possibility of slow-roll axionic inflation in the large volume limit of Swiss-Cheese Calabi-Yau orientifold compactifications of type IIB string theory. We also include one- and two-loop corrections to the Kaehler potential but find the same to be subdominant to the (perturbative and non-perturbative) alpha' corrections. The NS-NS axions provide a flat direction for slow-roll inflation to proceed from a saddle point to the nearest dS minimum.
description: 1+15 pages, LaTeX; some errors corrected and now get number of e-foldings as 60 - this supersedes the published version
Constraining dust-driver relationships in global climate models using remote sensing observations over Australia
Creators: name: Shaylor, Marie
Publisher: name: Imperial College London
Year: 2023

description: Mineral dust is the most abundant aerosol by dry mass in the Earth’s atmosphere. Its interactions with our planet are wide-ranging and multidisciplinary in nature. It plays an important role in maintaining the net radiation budget of our planet by scattering and absorbing short and long-wave radiation, affecting cloud microphysics, and fertilizing distant ecosystems. Airborne mineral dust may also present a hazard to human health by decreasing air quality and acting as a catalyst to disease spread. However, due to the complexity of interactions, forcings, and feedbacks in which dust is involved, researchers are unsure of whether the increased dust loading over the past century has encouraged or hindered climate changes. It is crucial that researchers understand what changes may emerge in the future because of enhanced dust emissions in order to help inform environmental policy at both local and global levels. As a first stage in this thesis, satellite retrievals of aerosol optical depth (AOD) from two distinct algorithms, MAIAC and DB, are evaluated over a 20-year period (2001-2020 inclusive) to determine the suitability of each for deriving a climatology of Australian dust activity. Whilst both algorithms can retrieve AOD to a good standard, it is found that MAIAC slightly outperforms DB, although both algorithms show better performance over vegetated surfaces and reduced performance over land surfaces classed as bare. Following this, two databases of dust optical depth (DOD) are derived from MAIAC and DB and subsequently evaluated against ground truth, with the comparative advantages of each discussed. These dust observations are used as a basis to evaluate dust in the UKESM family of global climate models. In-depth testing and analysis of the key drivers of dust activity reveal that near-surface wind speeds and top-layer soil moisture are critical in simulating the observed interannual variability of DOD in Australia.
Nonperturbative evaluation of the diffusion rate in field theory at high temperatures
Creators: name: Bochkarev, Alexander
name: de Forcrand, Philippe
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Kramer's approach to the rate of the thermally activated escape from a metastable state is extended to field theory. Diffusion rate in the 1+1-dimensional Sine-Gordon model as a function of temperature and friction coefficient is evaluated numerically by solving the Langevin equation in real time. A clear crossover from the semiclassical to the high temperature domain is observed. The temperature behaviour of the diffusion rate allows one to determine the kink mass which is found equal to the corresponding classical value. The Kramer's predictions for the dependence on viscosity are qualitatively valid in this multidimensional case. In the limit of vanishing friction the diffusion rate is shown to coincide with the one obtained from the direct measurements of the conventional classical real-time Green function at finite temperature.
description: 21 pages, figures upon request, BUTP-92/22
Screening Toxic Chemicals: How Accurate Must Tests Be?
Creators: name: Lave, Lester B.
name: Omenn, Gilbert S.
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: A decision analysis framework is used to explore the value of screening tests for carcinogenicity; Whether a test lowers the social cost of screening depends on the test's sensitivity, specificity, and c~st and the social cost of misclassification (exonerating carcinogenic chemicals or condemning noncarcinogenic chemicals). The model shows lhat the best screening test need .not he either the most accurate or the least expensive.
Masses of Nix and Hydra
Creators: name: Tholen, David J.
name: Buie, Marc W.
name: Grundy, William M.
name: Elliott, Garrett T.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A four-body orbit solution for the Pluto system yields GM values of 870.3 +/- 3.7, 101.4 +/- 2.8, 0.039 +/- 0.034, and 0.021 +/- 0.042 km3 sec-2 for Pluto, Charon, Nix, and Hydra, respectively. Assuming a Charon-like density of 1.63 gm cm-3, the implied diameters for Nix and Hydra are 88 and 72 km, leading to visual geometric albedos of 0.08 and 0.18, respectively, though with considerable uncertainty. The eccentricity of Charon's orbit has a significant nonzero value; however, the 0.030 +/- 0.009 deg yr-1 rate at which the line of apsides precesses is insufficient to explain the difference in the longitude of periapsis seen in the orbits fitted to the 1992-1993 and 2002-2003 data sets. The mean orbital periods for Hydra, Nix, and Charon are in the ratios of 6.064 +/- 0.006 : 3.991 +/- 0.007 : 1, but we have not identified any resonant arguments that would indicate the existence of a mean motion resonance between any pairs of satellites.
description: 14 pages, 6 figures, 6 tables
Identifying Universality in Warm Inflation
Creators: name: Berera, Arjun
name: Mabillard, Joel
name: Pieroni, Mauro
name: Ramos, Rudnei O.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Ideas borrowed from renormalization group are applied to warm inflation to characterize the inflationary epoch in terms of flows away from the de Sitter regime. In this framework different models of inflation fall into universality classes. Furthermore, for warm inflation this approach also helps to characterise when inflation can smoothly end into the radiation dominated regime. Warm inflation has a second functional dependence compared to cold inflation due to dissipation, yet despite this feature, it is shown that the universality classes defined for cold inflation can be consistently extended to warm inflation.
description: 20 pages, 5 figures, 1 appendix
Pricing American options by exercise rate optimization
Creators: name: Bayer, Christian
name: Tempone, Raúl F.
name: Wolfers, Sören
Publisher: name: Weierstrass Institute
Year: 2019
Subjects: subject: Computational finance
subject: American option pricing
subject: stochastic optimization problem
subject: Monte Carlo
subject: multivariate approximation
subject: rough volatility
subject: 91G60
subject: 91G20
subject: 49M20

description: We present a novel method for the numerical pricing of American options based on Monte Carlo simulation and the optimization of exercise strategies. Previous solutions to this problem either explicitly or implicitly determine so-called optimal exercise regions, which consist of points in time and space at which a given option is exercised. In contrast, our method determines the exercise rates of randomized exercise strategies. We show that the supremum of the corresponding stochastic optimization problem provides the correct option price. By integrating analytically over the random exercise decision, we obtain an objective function that is differentiable with respect to perturbations of the exercise rate even for finitely many sample paths. The global optimum of this function can be approached gradually when starting from a constant exercise rate. Numerical experiments on vanilla put options in the multivariate Black-Scholes model and a preliminary theoretical analysis underline the efficiency of our method, both with respect to the number of time-discretization steps and the required number of degrees of freedom in the parametrization of the exercise rates. Finally, we demonstrate the flexibility of our method through numerical experiments on max call options in the classical Black-Scholes model, and vanilla put options in both the Heston model and the non-Markovian rough Bergomi model.
Renormalisation of lattice currents and the calculation of decay constants for dynamical staggered fermions
Creators: name: Altmeyer, R.
name: Born, K. D.
name: Goeckeler, M.
name: Horsley, R.
name: Laermann, E.
name: Schierholz, G.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: A numerical calculation of the lattice staggered renormalisation constants at $β= 5.35$, $m = 0.01$ is presented. It is seen that there are considerable non-perturbative effects present. As an application the vector decay constant $f_ρ$ is estimated. (LAT92 contribution, one LATEX file with 3 postscript figures appended.)
description: 5 pages, HLRZ preprint 92-70
Status of Ichthyofaunal Diversity and Seasonal Physico-Chemical Variations of Charipunia Beel, Morigaon District, Assam
Creators: name: Bhagyashree Das
Publisher: name: The Science world a Monthly e magazine
Year: 2025
Subjects: subject: Veterinary sciences
subject: FOS: Veterinary sciences

description: This study was conducted to evaluate the ichthyofaunal diversity, plankton dynamics, and seasonal variations in key physico-chemical parameters of Charipunia Beel, Morigaon district, Assam, over a one-year period (May 2022 to April 2023). A total of 26 fish species across 18 genera, 11 families, and 4 orders were identified. Water quality parameters remained within favorable ranges for fish production, indicating the beel's ecological stability. However, the presence of Vulnerable and Near Threatened fish species underscores the need for targeted conservation and sustainable management practices.
Coarse-graining Langevin dynamics using reduced-order techniques
Creators: name: Ma, Lina
name: Li, Xiantao
name: Liu, Chun
Publisher: name: arXiv
Year: 2018
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65

description: This paper considers the reduction of the Langevin equation arising from bio-molecular models. To facilitate the construction and implementation of the reduced models, the problem is formulated as a reduced-order modeling problem. The reduced models can then be directly obtained from a Galerkin projection to appropriately defined Krylov subspaces. The equivalence to a moment-matching procedure, previously implemented in , 2), is proved. A particular emphasis is placed on the reduction of the stochastic noise, which is absent in many order-reduction problems. In particular, for order less than six we can show the reduced model obtained from the subspace projection automatically satisfies the fluctuation-dissipation theorem. Details for the implementations, including a bi-orthogonalization procedure and the minimization of the number of matrix multiplications, will be discussed as well.
Scientific and cost-effectiveness criteria in selecting batteries of short-term tests
Creators: name: Omenn, Gilbert S.
name: Lave, Lester B
Publisher: name: Carnegie Mellon University
Year: 2012
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: The scientific and cost-effectiveness criteria introduced in this paper can be applied to published datasets and current and proposed batteries of short-term tests. The reports in the current volume will provide a wealth of additional material for such evaluations, but more systematically obtained information will be necessary to assess both the internal and external validity of these tests. Individual tests and batteries of tests should be standardized, employ positive controls, generate results capable of quantitative analyses that may make dichotomous classification as “positive” and “negative” obsolete, be interpreted in light of mechanisms of action, and be cost-effective on a grand scale. For regulatory purposes our long-term goal should be to replace the whole animal lifetime bioassay with an appropriate and cost-effective set of short-term tests.
Coherent transport structures in magnetized plasmas II: Numerical results
Creators: name: Di Giannatale, G.
name: Falessi, M. V.
name: Grasso, D.
name: Pegoraro, F.
name: Schep, T. J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In a pair of linked articles (called Article I and II respectively) we apply the concept of Lagrangian Coherent Structures borrowed from the study of Dynamical Systems to magnetic field configurations in order to separate regions where field lines have different kind of behavior. In the present article, article II, by means of a numerical procedure we investigate the Lagrangian Coherent Structures in the case of a two-dimensional magnetic configuration with two island chains that are generated by magnetic reconnection and evolve nonlinearly in time. The comparison with previous results, obtained by assuming a fixed magnetic field configuration, allows us to explore the dependence of transport barriers on the particle velocity.
High pressure Raman study of La$_{1-x}$Ca$_x$MnO$_{3-δ}$ manganites
Creators: name: Sacchetti, A.
name: Corridoni, T.
name: Arcangeletti, E.
name: Postorino, P.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report on a high-pressure Raman study on two members of the La$_{1-x}$Ca$_x$MnO$_{3-δ}$ manganite family ($x=0.20$, $δ=0$ and $δ=0.08$). The results obtained for the $δ=0$ sample show a different behavior in the low and high pressure regimes ascribed to the onset of a new pressure-activated interaction previously invoked in other manganite compounds. The comparison of our results with literature data gives further support to the identification of the Jahn-Teller active stretching mode and shows that pressure-induced octahedral symmetrization is more effective in systems exhibiting a lower metallic character. On the contrary the new interaction sets in at pressure which decreases on increasing the metallic character of the system indicating a relevant role of the Mn-Mn hopping integral in its activation.
description: 4 pages, 3 figure, submitted to Phys. Rev. B
School finance reform: Assessing general equilibrium effects
Creators: name: Epple, Dennis
name: Ferreyra, Maria Marta
Publisher: name: Carnegie Mellon University
Year: 2011
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: In 1994 the state of Michigan implemented one of the most comprehensive school finance reforms undertaken to date in any of the states. Understanding the effects of the reform is thus of value in informing other potential reform initiatives. In addition, the reform and associated changes in the economic environment provide an opportunity to assess whether a simple general equilibrium model can be of value in framing the study of such reform initiatives. In this paper, we present and use such a model to derive predictions about the effects of the reform on housing prices and neighborhood demographic compositions. Broadly, our analysis implies that the effects of the reform and changes in the economic environment are likely to have been reflected primarily in housing prices and only modestly on neighborhood demographics. We find that evidence for the Detroit metropolitan area from the decade encompassing the reform is largely consistent with the predictions of the model.
Lettre de Antoine Gouan à Jean-François Séguier, 1766-11-29
Creators: name: Gouan, Antoine
name: Gouan, Antoine
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Botanique

description: [fol. 105] [Pouvez-vous nous envoyer quelque umbellifere rare en motte, des fritillaires Persica, des imperiales, c’est le temps]

Je languissais bien, mon cher M. Séguier, que mon homme (ancien juge du petit scel) revint de sa campagne. Je l’ai vu, Vidi, Vici. Voici donc ce qu’il m’a dit.
1° qu’il avait jadis prêté, donné & c plusieurs manuscrits à M. de vos compatriotes touchant le petit scel. Son nom m’a échappé, mais autant que je puis me le rappeler il s’approche du mot fidié, fedié, perdié, guerie & c Vous pouvez à peu près deviner ce mot là. M. Barre m’a dit encore que les manuscrits qui vous étaient parvenus pouvaient bien être ceux qu’il avait donné à son ami.
2° Que si vous vouliez envoyer un petit sommaire ou mémoire raisonné, il pourrait facilement savoir ce qui peut vous manquer. Ce sommaire ou mémoire doit dire quelle est la matière dont traitent les manuscrits que vous avez, le nombre des articles et en un mot une espèce d’index et que lorsque vous nous l’aurez communiqué, il se fera un vrai plaisir de travailler à vous obliger. Ergo. J’attends votre réponse. Profitez, s’il vous plait du passage au départ de vos amis pour les états, afin de me faire passer le cahier des oignons, ail, porreau & c. avec le Zanoni historia, le Haller opuscule de allio, et Rudbek Elys. Qui est cité dans Linnaeus Sp. Pl. de Alliis et dont je n’ai rien vu dans votre bibliothèque botanique ni dans les appendices, le tout vous sera renvoyé en bon ordre par une bonne occasion. 
Je suis avec toute l’amitié possible votre très humble serviteur et ami.

 Gouan

Le 29 novembre 1766.

Cité :
Rudbek, Olaus, Campi Elysii, I et II, Upsala, 1701, 4 vol.
description: Source: [établissement de conservation] Nîmes, Bibliothèque Carré d'Art [cote] ms. 144, fol. 105
Generation of large-scale magnetic fields due to fluctuating $α$ in shearing systems
Creators: name: Jingade, Naveen
name: Singh, Nishant K.
name: Sridhar, S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: We explore the growth of large-scale magnetic fields in a shear flow, due to helicity fluctuations with a finite correlation time, through a study of the Kraichnan-Moffatt model of zero-mean stochastic fluctuations of the $α$ parameter of dynamo theory. We derive a linear integro-differential equation for the evolution of large-scale magnetic field, using the first-order smoothing approximation and the Galilean invariance of the $α$-statistics. This enables construction of a model that is non-perturbative in the shearing rate $S$ and the $α$-correlation time $τ_α$. After a brief review of the salient features of the exactly solvable white-noise limit, we consider the case of small but non-zero $τ_α$. When the large-scale magnetic field varies slowly, the evolution is governed by a partial differential equation. We present modal solutions and conditions for the exponential growth rate of the large-scale magnetic field, whose drivers are the Kraichnan diffusivity, Moffatt drift, Shear and a non-zero correlation time. Of particular interest is dynamo action when the $α$-fluctuations are weak; i.e. when the Kraichnan diffusivity is positive. We show that in the absence of Moffatt drift, shear does not give rise to growing solutions. But shear and Moffatt drift acting together can drive large scale dynamo action with growth rate $γ\propto |S|$.
description: 19 pages, 4 figures, Accepted in Journal of Plasma Physics
Home 3D printing: exploring owner engagement with desktop technologies in the UK
Creators: name: Skelton, Jacquelyn
Publisher: name: Loughborough University
Year: 2024

description: This thesis offers a rich picture of owner engagement with desktop 3D printing technologies in the UK based on the findings from a literature review, online survey study (107 participants), and semi-structured interviews study (15 participants), which can guide future research. The motivation for this project emerged from a desire to investigate whether repair accounted for a significant proportion of home 3D printing projects, stemming from a concern that bringing 3D printers into the home might lead to more—rather than less—household waste.
Disrupted iron homeostasis in the vascular endothelium: implications for health and disease
Creators: name: Almaghlouth, Fatma
Publisher: name: Imperial College London
Year: 2023

description: Introduction: This thesis explores the impact of impaired iron regulation and its associated genomic burden on the vascular endothelium. It focuses on the development of diseases like hereditary haemorrhagic telangiectasia (HHT) and examines the link between iron regulation and susceptibility to SARS-CoV-2 viral entry, particularly through the regulation of the Hepcidin/Ferroportin axis in the context of COVID-19 infection. Approach and Methods: The research was carried out in three main phases. Initially, gene variants linked to iron regulation were analyzed using metrics such as GDI and RVIS. This was followed by silencing key iron regulation genes in Human Pulmonary Artery Endothelial Cells (hPAECs) using siRNA and conducting RNA sequencing to identify differentially expressed genes. The final phase involved investigating the ACE2 co-receptor in hPAECs and assessing the effects of Tocilizumab (TCZ), LY2928057 (LY), and Ferroportin knockdown on ACE2 regulation to elucidate SARS-CoV-2 entry mechanisms. Methods including cell culture, qPCR, and western blotting were utilized. Conclusion: This study elucidates key gene expression changes due to VHL knockdown, offering insights into SARS-CoV-2's influence on ACE2 expression in pulmonary endothelial cells. We identified crucial genes in angiogenesis and hypoxia response (VEGFA, ANGPT1), and pathways like HIF-1, crucial under hypoxic conditions similar to those in SARS-CoV-2-induced lung environments. These alterations could have significant implications for systemic inflammation and the pathophysiology of Hereditary Hemorrhagic Telangiectasia (HHT). Changes in signalling pathways, such as EGFR, PDGFC, RAF1, ERN1, and DUSP7, underline the importance of cellular defence against viral infections and their potential effects on ACE2 regulation. This could be particularly relevant in HHT, where such dysregulation might exacerbate vascular instability and inflammatory responses. Furthermore, the roles of TNF in inflammation and TGF-β in cell growth and immune regulation suggest their influence on ACE2 expression and susceptibility to infection, critical in understanding the intersection between viral infections, systemic inflammation, and HHT progression. These findings highlight the complex role of VHL in endothelial cell function under hypoxia, paving the way for further research into the dynamics of SARS-CoV-2 infection and its implications for vascular diseases like HHT.
TEI P5: Guidelines for Electronic Text Encoding and Interchange
Creators: name: TEI Consortium
Publisher: name: Zenodo
Year: 2008
Subjects: Text Encoding
Digital Humanities
Text Encoding Initiative

description: Find more information about the Text Encoding Initative at https://tei-c.org P5 version 1.1 release notes This is a maintenance release, implementing several changes agreed following the review of outstanding feature requests undertaken at the Council meeting in Galway in April (see Working Paper TCW12 for a complete list) In addition to these specific responses to feature requests, a number of minor corrections and clarifications in the text of the Guidelines have been made. Examples of these include: make foliation element repeatable, as stated in the text of the Guidelines clarify the distinction between conformable and conforming schemas remove lurking references to a non-existent 'divn' class add discussion of use of milestone tagging to mark speaker changes etc. tidy up usage of the att element in the text of the Guidelines harmonise and clarify usage of age attribute on person and personGrp permit text as content for interp element Several changes were made in the tool chain used to produce the Guidelines, most of these with a view to producing an enhanced PDF version for publication on paper. Changes have also been made in the stylesheets controlling the visualisation of the Guidelines on the web, in response to criticisms of earlier releases. These changes do not, of course, affect the text of the guidelines proper. The I18N project continues; at this release, substantial amounts of new material have been added in Chinese, Japanese, and Spanish. A systematic review of element specifications was undertaken; each specification now includes an example of its usage. Home Feedback Date: 7 July 2008

 released under the Creative Commons Attribution 3.0 Unported License http://creativecommons.org/licenses/by/3.0/
Magnetic Moment Collapse-Driven Mott Transition in MnO
Creators: name: Kunes, Jan
name: Lukoyanov, Alexey V.
name: Anisimov, Vladimir I.
name: Scalettar, Richard T.
name: Pickett, Warren E.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The metal-insulator transition in correlated electron systems, where electron states transform from itinerant to localized, has been one of the central themes of condensed matter physics for more than half a century. The persistence of this question has been a consequence both of the intricacy of the fundamental issues and the growing recognition of the complexities that arise in real materials, even when strong repulsive interactions play the primary role. The initial concept of Mott was based on the relative importance of kinetic hopping (measured by the bandwidth) and on-site repulsion of electrons. Real materials, however, have many additional degrees of freedom that, as is recently attracting note, give rise to a rich variety of scenarios for a ``Mott transition.'' Here we report results for the classic correlated insulator MnO which reproduce a simultaneous moment collapse, volume collapse, and metallization transition near the observed pressure, and identify the mechanism as collapse of the magnetic moment due to increase of crystal field splitting, rather than to variation in the bandwidth.
description: 18 pages, 5 figure
School Choice with Controlled Choice Constraints: Hard Bounds versus Soft Bounds
Creators: name: Ehlers, Lars
name: Hafalir, Isa
name: Yenmez, Mehmet
name: Yildirim, Muhammed A.
Publisher: name: Carnegie Mellon University
Year: 1998
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: Controlled choice over public schools attempts giving options to parents while maintaining diversity, often enforced by setting feasibility constraints with hard upper and lower bounds for each student type. We demonstrate that there might not exist assignments that satisfy standard fairness and non-wastefulness properties; whereas con- strained non-wasteful assignments which are fair for same type students always exist. We introduce a "controlled" version of the deferred acceptance algorithm with an improvement stage (CDAAI) that finds a Pareto optimal assignment among such assignments. To achieve fair (across all types) and non-wasteful assignments, we propose the control constraints to be interpreted as soft bounds-flexible limits that regulate school priorities. In this setting, a modified version of the deferred acceptance algorithm (DAASB) finds an assignment that is Pareto optimal among fair assignments while eliciting true preferences. CDAAI and DAASB provide two alternative practical solutions depending on the interpretation of the control constraints.
School Choice with Consent
Creators: name: Kesten, Onur
Publisher: name: Carnegie Mellon University
Year: 2008
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: An increasingly popular practice for student assignment to public schools in the U.S. is the use of school choice systems. The celebrated Gale-Shapley student-optimal stable mechanism (SOSM) has recently replaced two de…ficient student assignment mechanisms that were in use in New York City and Boston. We provide theoretical evidence that the SOSM outcome may produce large welfare losses. Then we propose an efficiency adjusted deferred acceptance mechanism (EADAM) that allows a student to consent to waive a certain priority that has no effect on his assignment. Under EADAM a consenting student causes himself no harm, but may help many others bene…fit as a consequence. We show that EADAM can recover any welfare losses due to SOSM while also preserving immunity against strategic behavior in a particular way. It is also possible to use EADAM to eliminate welfare losses due to randomly breaking ties in student priorities. I
Natural CP Violation Criteria for the Minimal Supersymmetric Standard Model
Creators: name: Garisto, Robert
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: $CP$ violating effects in the Minimal Supersymmetric Standard Model (MSSM) can lead to excessively large contributions to the neutron EDM (\dn). We write criteria which ensure that the low energy supergravity (SUGRA) parametrization of the MSSM does not require fine-tunings or large mass scales to evade the constraint from \dn, and consider the implications on SUGRA theories. In particular, we show that in the Polonyi model, two of the mass scales are in general complex, meaning that model does not naturally avoid a large \dn\ as is sometimes claimed.
description: 23pp (2 fig avail. on request), plain LATEX, TRI-PP-24 ('93) (Shortened version to appear in Nucl. Phys. B. One Feynman diagram added for clarity.)
Additional file 1 of Comparative and functional genomics of the ABC transporter superfamily across arthropods
Creators: name: Denecke, Shane
name: Rankić, Ivan
name: Driva, Olympia
name: Kalsi, Megha
name: Luong, Ngoc Bao Hang
name: Buer, Benjamin
name: Nauen, Ralf
name: Geibel, Sven
name: Vontas, John
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. The total number of ABC transporters in each species (x-axis) was calculated for each species included in the analysis.
Probing the Ionic Dielectric Constant Contribution in the Ferroelectric Phase of the Fabre-Salts
Creators: name: de Souza, Mariano
name: Squillante, Lucas
name: Sônego, Cesar
name: Menegasso, Paulo
name: Foury-Leylekian, Pascale
name: Pouget, Jean-Paul
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In strongly correlated organic materials it has been pointed out that charge-ordering could also achieve electronic ferroelectricity at the same critical temperature $T_{co}$. A prototype of such phenomenon are the quasi-one dimensional (TMTTF)$_2X$ Fabre-salts. However, the stabilization of a long-range ferroelectric ground-state below $T_{co}$ requires the break of inversion symmetry, which should be accompanied by a lattice deformation. In this work we investigate the role of the monovalent counter-anion $X$ in such mechanism. For this purpose, we measured the quasi-static dielectric constant along the $c^{*}$-axis direction, where layers formed by donors and anions alternate. Our findings show that the ionic charge contribution is three orders of magnitude lower than the intra-stack electronic response. The $c^{*}$ dielectric constant ($ε'_{c^*}$) probes directly the charge response of the monovalent anion $X$, since the anion mobility in the structure should help to stabilize the ferroelectric ground-state. Furthermore, our $ε'_{c^*}$ measurements %conjugated with earlier investigations of the $c^*$ lattice thermal expansion, show that the dielectric response is thermally broaden below $T_{co}$ if the ferroelectric transition occurs in the temperature range where the anion movement begin to freeze in their methyl groups cavity. In the extreme case of the PF$_6$-H$_{12}$ salt, where $T_{co}$ occurs at the freezing point, a relaxor-type ferroelectricity is observed. Also, because of the slow kinetics of the anion sub-lattice, global hysteresis effects and reduction of the charge response upon successive cycling are observed. In this context, we propose that anions control the order-disorder or relaxation character of the ferroelectric transition of the Fabre-salts.
description: 8 pages, 7 figures. To appear in Physical Review B
Dual Superconductor Mechanism of Confinement on the Lattice
Creators: name: Cea, P.
name: Cosmai, L.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We investigate the dual superconductor mechanism of confinement for pure SU(2) lattice gauge theory in the maximally abelian gauge. We focus on the the dual Meissner effect. We find that the transverse distribution of the longitudinal chromoelectric field due to a static quark-antiquark pair satisfies the dual London equation. Moreover we show that the size of the flux tube scales according to asymptotic freedom.
description: LaTeX, 9 pages, 6 figures available as a PostScript file from L. Cosmai, BARI - TH 110/92
Scenarios to Explore Greenhouse Decisions
Creators: name: Lave, Lester B.
Publisher: name: Carnegie Mellon University
Year: 1996
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: The potential consequences of global climate change are disastrous. Anyone above a subsistence level of income cannot help thinking about the consequences of human activities that could make the Earth an inhospitable place. Unfortunately, uncertainties about the consequences of our actions are as large consequences. The climate effects of greenhouse gas emissions is largely unknown. as well as bad, e.g., moderate warming could be enormously beneficial, particularly one of the periodic ice ages. as the potential Climate change could be good if the Earth is headed toward I focus on what governments should be doing in response to the threat of anthropogenic global climate change. I propose to cut through the complexities of uncertainty by focusing on three essential areas for policy: (1) The relationship between emissions of greenhouse gases and global change climate. (2) The resulting effects on humans and the environment we ca~e about. And (3) the costs of reducing greenhouse gas emissions. To keep the analysis simple and transparent, I explore these three areas in a few "scenarios." The resulting analysis eliminates the myriad unessential detail that has prevented a clear view of what current policy should seek to accomplish. But the reader should be warned: caveat emptor.
Gender Differences in Liver Function Markers by BMI Categories in the C8 Health Study
Creators: name: Ranjita Misra
name: Raihan Khan
name: Bhandari, Ruchi
name: Sambamoorthi, Usha
name: Ducatman, Alan
Publisher: name: F1000 Research Limited
Year: 2019

description: Association between liver enzymes and adult obesity was assessed using the C8 data set.
Additional file 2 of Comparative and functional genomics of the ABC transporter superfamily across arthropods
Creators: name: Denecke, Shane
name: Rankić, Ivan
name: Driva, Olympia
name: Kalsi, Megha
name: Luong, Ngoc Bao Hang
name: Buer, Benjamin
name: Nauen, Ralf
name: Geibel, Sven
name: Vontas, John
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Figure S2. The predicted numbers of ABC transporters in the ABC_scan pipeline were benchmarked against previously published ABC transporter datasets. The % difference in total number of ABC transporters (y-axis) was plotted for each species (x-axis). For all species tested, the difference was less than 10% (dotted line).