cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Simulation of nonequilibrium spin dynamics in quantum dots subjected to periodic laser pulses
Creators: name: Schering, Philipp
name: Scherer, Philipp W.
name: Uhrig, Götz S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Large-scale simulations of the spin dynamics in quantum dots subjected to trains of periodic laser pulses enable us to describe and understand related experiments. By comparing the data for different models to experimental results, we gain an improved understanding of the relevant physical mechanisms. Using sophisticated numerical approaches and an efficient implementation combined with extrapolation arguments, nonequilibrium stationary states are reached for parameter ranges close to the ones in real experiments. With the help of high performance computing, we can tune the experimental parameters to guide future experimental research. Importantly, our simulations reveal the possibility of resonant spin amplification in Faraday geometry, i.e., when a longitudinal magnetic field is applied to the quantum dots.
description: Preprint of the following chapter: P. Schering, P.W. Scherer, and G.S. Uhrig, "Simulation of Nonequilibrium Spin Dynamics in Quantum Dots Subjected to Periodic Laser Pulses", published in High Performance Computing in Science and Engineering '20, edited by W.E. Nagel, D.H. Kr\"oner, and M.M. Resch, 2021, Springer, Cham. Final authenticated version: https://doi.org/10.1007/978-3-030-80602-6_8
Estimating the social rate of time preference for changes in mortality risk; a contingent valuation approach
Creators: name: Womeldorff, Thomas David
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 38
subject: Economics

description: The objective of this study is to determine the appropriateness of using surveys to estimate the social rate of time preference for a change in mortality risk. Three measures of the appropriateness were used: the degree of bias evident in survey results, the reliability of the survey data as measured by context validity, and a comparison with the results of previous studies. A survey was designed to estimate the social rate of time preference (SRTP) for a reduction in mortality risk resulting from the removal of toxics from the water supply. The survey design was pretested and then face-to-face surveys were conducted with 100 residents of Arlington, Virginia. The median social rate of time preference was 0.956. Bias was significant and generally biased SRTP upward. However, it was not overwhelming suggesting biases can be controlled for. A model of determinants of SRTP was estimated and was significant lending validity to the reliability of the survey data. Finally, the results are comparable to those of the only previous study estimating SRTP for changes in mortality risk. It is concluded that face-to-face surveys are effective in revealing the social rate of time preference for a well-defined benefit stream though the potential for biased responses is not insignificant.
An Adaptive Penalty Method for Inequality Constrained Minimization Problems
Creators: name: Boon, Wietse M.
name: Nordbotten, Jan M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: The primal-dual active set method is observed to be the limit of a sequence of penalty formulations. Using this perspective, we propose a penalty method that adaptively becomes the active set method as the residual of the iterate decreases. The adaptive penalty method (APM) therewith combines the main advantages of both methods, namely the ease of implementation of penalty methods and the exact imposition of inequality constraints inherent to the active set method. The scheme can be considered a quasi-Newton method in which the Jacobian is approximated using a penalty parameter. This spatially varying parameter is chosen at each iteration by solving an auxiliary problem.
Nuclear moments of inertia and wobbling motions in triaxial superdeformed nuclei
Creators: name: Matsuzaki, Masayuki
name: Shimizu, Yoshifumi R.
name: Matsuyanagi, Kenichi
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The wobbling motion excited on triaxial superdeformed nuclei is studied in terms of the cranked shell model plus random phase approximation. Firstly, by calculating at a low rotational frequency the γ-dependence of the three moments of inertia associated with the wobbling motion, the mechanism of the appearance of the wobbling motion in positive-γnuclei is clarified theoretically -- the rotational alignment of the πi_{13/2} quasiparticle(s) is the essential condition. This indicates that the wobbling motion is a collective motion that is sensitive to the single-particle alignment. Secondly, we prove that the observed unexpected rotational-frequency dependence of the wobbling frequency is an outcome of the rotational-frequency dependent dynamical moments of inertia.
description: 22 pages, 10 figures, to appear in Phys. Rev. C
Fumariales Bercht. & J.Presl.
Creators: name: Reveal, James L.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Fumariales

description: Fumariales
 Bercht. & J.Presl, P ř ir. Rostlin: 216. January–April 1820 (Fumariae), predates Link, Handbuch 2: 274. 4–11 July 1829—Fumariaceae Marquis (1820).
description: Published as part of Reveal, James L., 2011, New ordinal names established by changes to the botanical code, pp. 42-44 in Phytotaxa 30 on page 43, DOI: 10.11646/phytotaxa.30.1.2, http://zenodo.org/record/4894455
Liberalization of the International Capital Markets: Effects on Taxation, Cost of Public Funds and Income Redistribution
Creators: name: Razin, Assaf
name: Sadka, Efraim
name: Razin, Assaf
name: Sadka, Efraim
Publisher: name: Unknown
Year: 1988
Subjects: Financial Economics
Public Economics

description: International-capital market integration has become a key policy issue in the prospective integration of Europe of 1992. In this context this paper provides a theoretical analysis of the effects of relaxing restrictions on the international flow of capital on the fiscal branch of government: the optimal provision of public goods, the structure of taxation and income redistribution policies. The major findings are: (a) income from investment abroad should be taxed at the same rate as income from domestic sources; (b) the cost of public funds falls and the supply of public goods rises if restrictions on international capital flows are relaxed; and (c) the amount of income redistributions, specifically the value of the demogrant, increases with the international-capital market liberalization.
Tests of the Gravitational Inverse-Square Law
Creators: name: Adelberger, E. G.
name: Heckel, B. R.
name: Nelson, A. E.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We review recent experimental tests of the gravitational inverse-square law and the wide variety of theoretical considerations that suggest the law may break down in experimentally accessible regions.
description: 81 pages, 10 figures, submitted by permission of the Annual Review of Nuclear and Particle Science. Final version of this material is scheduled to appear in the Annual Review of Nuclear and Particle Science Vol. 53, to be published in December 2003 by Annual Reviews, http://AnnualReviews.org
Additional file 19 of Neuron ID dataset facilitates neuronal annotation for whole-brain activity imaging of C. elegans
Creators: name: Toyoshima, Yu
name: Wu, Stephen
name: Kanamori, Manami
name: Sato, Hirofumi
name: Jang, Moon Sun
name: Suzu Oe
name: Murakami, Yuko
name: Teramoto, Takayuki
name: Chanhyun Park
name: Yuishi Iwasaki
name: Ishihara, Takeshi
name: Yoshida, Ryo
name: Iino, Yuichi
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 19: Figure S12. Variation of relative position of cell pairs. Variation of relative position of cell pairs. Orders of cells and colors are the same as in Fig. 2c.
Hernandiales Bercht. & J.Presl.
Creators: name: Reveal, James L.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Hernandiales

description: Hernandiales
 Bercht. & J.Presl, P ř ir. Rostlin: 235. January–April 1820 (Hernandiae), predates Mart., Consp. Regn. Veg.: 15. September–October 1835—Hernandiaceae Blume (1826).
description: Published as part of Reveal, James L., 2011, New ordinal names established by changes to the botanical code, pp. 42-44 in Phytotaxa 30 on page 43, DOI: 10.11646/phytotaxa.30.1.2, http://zenodo.org/record/4894455
A new phosphate ion selective electrode
Creators: name: Carey, Clifton Manning
Publisher: name: American University
Year: 2023

description: This project describes the development of a new dibasic phosphate ion selective electrode. A series of neutral ion carriers that selectively complex phosphate ions were synthesized and tested for use in a phosphate ion selective electrode. The best phosphate ionophore was the macrocyclic polyamine (3-decyl-1,5,8-triazacyclodecane-2,4-dione, N$\sb3$-cyclic amine). The linear range of the phosphate ion selective electrode made with this ionophore is from 1 $\times$ 10$\sp{-6}$ to 0.1 mol/L, with a limit of detection of 2 $\times$ 10$\sp{-7}$ mol/L. The slope of response curve is near-Nernstian at $\sim$29 mV per concentration decade. Further, this electrode is not affected at all by changes in pH between 6 and 8, and is not greatly affected by changes in pH between 5 and 11. The selectivity pattern for this electrode is: HPO$\sbsp{4}{2-}$ $\gg$ Cl$\sp- >$ NO$\sbsp{3}{-} >$ SO$\sbsp{4}{2-}$ = Lac$\sp- \gg$ Ace$\sp-$. Benefits arising from this study are: (1) the development of a new orthophosphate selective electrode that has superior selectivity and sensitivity for dibasic orthophosphate (HPO$\sbsp{4}{2-}$); (2) a comprehensive review of the literature relevant to phosphate ion selective electrodes, including construction and response characteristics; (3) the evaluation of some of the phosphate ion selective electrodes described in the literature, including their construction and response characteristics; (4) the measurement of the activity of dibasic phosphate ions in hydroxyapatite solutions; (5) and, for the first time, the direct measurement of dibasic phosphate activities in complex biological fluids.
The clinical epidemiology of allergic contact dermatitis
Creators: name: Rastogi, Supriya
Publisher: name: DigitalHub. Galter Health Sciences Library & Learning Center
Year: 2018
Subjects: subject: public health
subject: Dermatitis, Allergic Contact
subject: Allergens
subject: United States
subject: Dermatitis, Allergic Contact/epidemiology

description: Background: Allergic contact dermatitis (ACD) is a common dermatologic diagnosis affecting over 13million patients annually in the United States. Despite its prevalence, limited research has been conducted regarding its clinical epidemiology. The development of contact dermatitis can vary based on genetics, environmental exposures, and co-morbidities such as atopic dermatitis (AD). This project examined the relationship of sex, race, age, and socioeconomic status with the risk of developing allergic contact dermatitis. A secondary goal of this project was to determine the predictors of and relevant allergens in ACD among patients with AD.Materials: We performed a retrospective chart review of 395 adults who were patch-tested at the Northwestern Medicine patch-testing clinic from 2014-2017. Patients were patch-tested with the North American Contact Dermatitis Group (NACDG) standard series and a supplemental allergen series. Demographic data such as sex, age, race, insurance,birthplace, and zip code (as a surrogate for income) were collected. Chi square tests and multivariable logistic regression models were used to estimate adjusted odds ratio and 95% confidence intervals.Results: There were no associations between sex, age, race, insurance, birthplace and the development of ACD. However, individuals estimated to be making less than the median income had an increased risk of developing allergic contact dermatitis (adjustedodds ratio [95% confidence interval] (3.50 [1.36 9.02]). AD patients (n=97) had significantly higher rates of positive patch test reactions to ingredients in their personal care products or topical medicaments, including lanolin (P=0.03), quaternium-15 (P=0.04), fragrance mix I (P=0.008), cinnamal (P=0.02), neomycin (P=0.02), bacitracin (P=0.04), chlorhexidine (P=0.04), and budesonide (P=0.01).Conclusions: Low income was the only demographic factor found to be associated with the development of ACD. Patients with AD did not have higher rates of positive patch test reactions overall. However, they had higher rates of positive patch test reactions tomultiple ingredients in their personal care products and topical steroid and antibiotic medicaments. Future research is needed to understand the risk factors associated with ACD to better predict and prevent this burdensome disease.
A new phosphate ion selective electrode
Creators: name: Carey, Clifton Manning
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3401
subject: Analytical chemistry

description: This project describes the development of a new dibasic phosphate ion selective electrode. A series of neutral ion carriers that selectively complex phosphate ions were synthesized and tested for use in a phosphate ion selective electrode. The best phosphate ionophore was the macrocyclic polyamine (3-decyl-1,5,8-triazacyclodecane-2,4-dione, N$\sb3$-cyclic amine). The linear range of the phosphate ion selective electrode made with this ionophore is from 1 $\times$ 10$\sp{-6}$ to 0.1 mol/L, with a limit of detection of 2 $\times$ 10$\sp{-7}$ mol/L. The slope of response curve is near-Nernstian at $\sim$29 mV per concentration decade. Further, this electrode is not affected at all by changes in pH between 6 and 8, and is not greatly affected by changes in pH between 5 and 11. The selectivity pattern for this electrode is: HPO$\sbsp{4}{2-}$ $\gg$ Cl$\sp- >$ NO$\sbsp{3}{-} >$ SO$\sbsp{4}{2-}$ = Lac$\sp- \gg$ Ace$\sp-$. Benefits arising from this study are: (1) the development of a new orthophosphate selective electrode that has superior selectivity and sensitivity for dibasic orthophosphate (HPO$\sbsp{4}{2-}$); (2) a comprehensive review of the literature relevant to phosphate ion selective electrodes, including construction and response characteristics; (3) the evaluation of some of the phosphate ion selective electrodes described in the literature, including their construction and response characteristics; (4) the measurement of the activity of dibasic phosphate ions in hydroxyapatite solutions; (5) and, for the first time, the direct measurement of dibasic phosphate activities in complex biological fluids.
Ultracold atoms confined in rf-induced two-dimensional trapping potentials
Creators: name: Colombe, Yves
name: Knyazchyan, Elena
name: Morizot, Olivier
name: Mercier, Brigitte
name: Lorent, Vincent
name: Perrin, Helene
Publisher: name: arXiv
Year: 2004
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present the experimental implementation of a new trap for cold atoms proposed by O. Zobay and B. M. Garraway. It relies on adiabatic potentials for atoms dressed by a rf field in an inhomogeneous magnetic field. This trap is well suited to confine atoms tightly along one direction to produce a two-dimensional atomic gas. We transferred ultracold atoms into this trap, starting either from thermal samples or Bose--Einstein condensates. In the latter case, technical noise during the loading stage caused heating and prevented us from observing 2D BECs.
description: soumis a Europhysics Letters le 29 fevrier 2004
Hortensiales Bercht. & J.Presl.
Creators: name: Reveal, James L.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Hortensiales

description: Hortensiales
 Bercht. & J.Presl, P ř ir. Rostlin: 260. January–April 1820 (Hortensiae), predates J.Presl in Nowoèeská Bibl. [Wšobecný Rostl.] 7: 690. 1846—Hortensiaceae Martinov (1820).
description: Published as part of Reveal, James L., 2011, New ordinal names established by changes to the botanical code, pp. 42-44 in Phytotaxa 30 on page 43, DOI: 10.11646/phytotaxa.30.1.2, http://zenodo.org/record/4894455
Stellar rotation rates in Kepler eccentric (heartbeat) binaries obtained from r-mode signatures
Creators: name: Saio, Hideyuki
name: Kurtz, Donald W.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: R-mode oscillations in a rotating star produce characteristic signatures in a Fourier amplitude spectrum at frequencies related with the rotation frequency, which can be, in turn, used to obtain the surface rotation rate of the star. Some binary stars observed by Kepler indicate the presence of r~modes that are probably excited by the tidal effect. In this paper, we have obtained stellar rotation periods in 20 eccentric (heartbeat) binaries with r-mode signatures. The majority of the rotation periods are found to be comparable to pseudo-synchronous periods, in which the angular velocity of rotation is similar to the angular orbital motion of the companion at periastron. In particular, for the heartbeat stars with orbital periods longer than about 8\,d, all but one agree with pseudo-synchronous rotation. In contrast to a previous investigation by Zimmerman et al., our result supports the pseudo-synchronisation theory developed by Hut.
description: 13 pages, to appear in MNRAS
Stellar Abundances in Young and Intermediate Age GCs
Creators: name: Alvensleben, Uta Fritze -- v.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Globular Cluster (GC) formation seems to be a widespread mode of star formation in extreme starbursts triggered by strong interactions and mergers of massive gas-rich galaxies. We use our detailed chemically consistent evolutionary synthesis models for spiral galaxies to predict stellar abundances and abundance ratios of those second generation GCs as a function of their age or formation redshift. Comparison with observed spectra of young star clusters formed recently in an ongoing intercation (NGC 4038/39) and a merger remnant (NGC 7252) are encouraging. Abundances and abundance ratios (and their respective spreads) among young and intermediate cluster populations and among the red peak GCs of elliptical/S0 galaxies with bimodal GC color distributions are predicted to bear a large amount of information about those clusters' formation processes and environment. Not only the bright young clusters but also representative populations of "old" GCs in E/S0 galaxies are readily accessible to MOS on 10m class telescopes.
description: 2 pages, Latex, IAU JD04 Sydney 2003, to appear in Memorie della Societa Astronomica Italiana
A Methodist experiment in graduate education: John Fletcher Hurst and the founding of The American University, 1889-1914
Creators: name: Ross, William Edwin
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 39
subject: Education
classificationCode: 3903
subject: Education systems
classificationCode: 3904
subject: Specialist studies in education

description: The founding of The American University in 1891 was at once an extension of and a departure from the philosophical underpinnings of late nineteenth century higher education in the United States. Its founder, Methodist bishop John Fletcher Hurst, desired to create a German-style, graduate university in the Nation's Capital. Hurst viewed the proposed university as an intellectual antidote to the growing secularism in American higher education. At the same time, it would counteract the founding, in Washington, of The Catholic University of America a few years before. The new university would be a capstone, graduate institution to serve all of Protestantism. It would draw on the educational resources of Washington to become a university of "national" importance without direct federal assistance or control. In 1892, the General Conference of the Methodist Episcopal Church voted to support the university, with the proviso that it raise five million dollars in endowment before opening. The fund raising challenge grew harder a year later with the onset of the economic "Panic of 1893." In addition to financial uncertainty, Hurst's efforts suffered from contradictory goals, grandiose building plans, competition from existing Methodist institutions, and confusion over efforts to create a federally-funded, national university in Washington. The American University's problems persisted through Hurst's death in 1903, and the lackluster tenure of his successor, Bishop Charles C. McCabe. The university opened in 1914, only after the General Conference withdrew its endowment requirement and Chancellor Franklin Hamilton dispensed with Hurst's unrealistic educational vision. Hamilton's modest program depended upon the resources and experts of the federal government, and operated as such until 1924, when the university admitted undergraduates for the first time. In spite of Hurst's idealistic vision, his support for coeducation, and the operation of the university as a graduate institution, the early history of The American University has been largely ignored by educational historians. This study is intended to remedy this longstanding oversight.
Hydroleales Bercht. & J.Presl.
Creators: name: Reveal, James L.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Hydroleales

description: Hydroleales
 Bercht. & J.Presl, P ř ir. Rostlin: 247. January–April 1820 (Hydroleae), predates Mart., Consp. Regn. Veg.: 23. September–October 1835—Hydroleaceae R.Br. ex Edwards (1821).
description: Published as part of Reveal, James L., 2011, New ordinal names established by changes to the botanical code, pp. 42-44 in Phytotaxa 30 on page 43, DOI: 10.11646/phytotaxa.30.1.2, http://zenodo.org/record/4894455
Additional file 18 of Neuron ID dataset facilitates neuronal annotation for whole-brain activity imaging of C. elegans
Creators: name: Toyoshima, Yu
name: Wu, Stephen
name: Kanamori, Manami
name: Sato, Hirofumi
name: Jang, Moon Sun
name: Suzu Oe
name: Murakami, Yuko
name: Teramoto, Takayuki
name: Chanhyun Park
name: Yuishi Iwasaki
name: Ishihara, Takeshi
name: Yoshida, Ryo
name: Iino, Yuichi
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 18: Figure S11. Comparison of the synthetic atlas and the neuron ID dataset. (A) Visualization of the variation of the cell positions in synthetic atlas. The cells and colors are the same as Fig. 2a. (B) Distance of mean position of cells between the atlas and the neuron ID dataset. (C) Ratio of volume of ellipsoid (covariance of the positions of the cell) between the atlas and the neuron ID dataset. (D) Comparing the variation of relative positions of dataset and that of atlas. The color indicates how many times the neuron pair is co-detected in an animal of the neuron ID dataset.
The Dynamics of Inflation with Constant Deficit under Expected Regime Change
Creators: name: Bental, Benjamin
name: Eckstein, Zvi
name: Bental, Benjamin
name: Eckstein, Zvi
Publisher: name: Unknown
Year: 1988
Subjects: Financial Economics

description: A model that describes the dynamics of inflation with a fully anticipated stabilization program is developed. It is shown that with a constant deficit, an economy tends to stay at the neighborhood of the lower of the two state inflation rates that are compatible with the deficit. Further, increasing inflation rates prior to the stabilization are compatible only with deficits that are lower than the maximal feasible staedy- state deficits, and with a stabilization program that reduces the demand for real balances. If these conditions are not met, inflation decreases towards the stabilization date. It is argued that the data generated by actual inflationary episodes fit the conditions described above and corroborate the model.
Molecular docking and molecular dynamics simulation of Bacillus thuringiensis dehalogenase against haloacids, haloacetates and chlorpyrifos
Creators: name: Oyewusi, Habeebat Adekilekun
name: Huyop, Fahrul
name: Wahab, Roswanira Abdul
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: The high dependency and surplus use of agrochemical products have liberated enormous quantities of toxic halogenated pollutants into the environment and threaten the well-being of humankind. Herein, this study performed molecular docking, molecular dynamic (MD) simulations, molecular mechanics-Poisson Boltzmann Surface Area (MM-PBSA) calculations on the DehH2 from Bacillus thuringiensis, to identify the order of which the enzyme degrades different substrates, haloacids, haloacetate and chlorpyrifos. The study discovered that the DehH2 favored the degradation of haloacids and haloacetates (−3.3 − 4.6 kcal/mol) and formed three hydrogen bonds with Asp125, Arg201 and Lys202. Despite the inconclusive molecular docking result, chlorpyrifos was consistently shown to be the least favored substrate of the DehH2 in MD simulations and MM-PBSA calculations. Results of MD simulations revealed the DehH2-haloacid- (RMSD 0.15 − 0.25 nm) and DehH2-haloacetates (RMSF 0.05 − 0.25 nm) were more stable, with the DehH2-L-2CP complex being the most stable while the least was the DehH2-chlorpyrifos (RMSD 0.295 nm; RMSF 0.05 − 0.59 nm). The Molecular Mechanics Poisson-Boltzmann Surface Area calculations showed the DehH2-L-2CP complex (−24.27 kcal/mol) having the lowest binding energy followed by DehH2-MCA (−22.78 kcal/mol), DehH2-D-2CP (−21.82 kcal/mol), DehH2-3CP (−21.11 kcal/mol), DehH2-2,2-DCP (−18.34 kcal/mol), DehH2-2,3-DCP (−8.34 kcal/mol), DehH2-TCA (−7.62 kcal/mol), while chlorpyrifos was unable to spontaneously bind to DehH2 (+127.16 kcal/mol). In a nutshell, the findings of this study offer valuable insights into the rational tailoring of the DehH2 for expanding its substrate specificity and catalytic activity in the near future. Communicated by Ramaswamy H. Sarma
Sampling rare switching events in biochemical networks
Creators: name: Allen, Rosalind J.
name: Warren, Patrick B.
name: Wolde, Pieter Rein ten
Publisher: name: arXiv
Year: 2004
Subjects: subject: Molecular Networks (q-bio.MN)
subject: FOS: Biological sciences

description: Bistable biochemical switches are ubiquitous in gene regulatory networks and signal transduction pathways. Their switching dynamics, however, are difficult to study directly in experiments or conventional computer simulations, because switching events are rapid, yet infrequent. We present a simulation technique that makes it possible to predict the rate and mechanism of flipping of biochemical switches. The method uses a series of interfaces in phase space between the two stable steady states of the switch to generate transition trajectories in a ratchet-like manner. We demonstrate its use by calculating the spontaneous flipping rate of a symmetric model of a genetic switch consisting of two mutually repressing genes. The rate constant can be obtained orders of magnitude more efficiently than using brute-force simulations. For this model switch, we show that the switching mechanism, and consequently the switching rate, depends crucially on whether the binding of one regulatory protein to the DNA excludes the binding of the other one. Our technique could also be used to study rare events and non-equilibrium processes in soft condensed matter systems.
description: 9 pages, 6 figures, last page contains supplementary information
A Methodist experiment in graduate education: John Fletcher Hurst and the founding of The American University, 1889-1914
Creators: name: Ross, William Edwin
Publisher: name: American University
Year: 2023

description: The founding of The American University in 1891 was at once an extension of and a departure from the philosophical underpinnings of late nineteenth century higher education in the United States. Its founder, Methodist bishop John Fletcher Hurst, desired to create a German-style, graduate university in the Nation's Capital. Hurst viewed the proposed university as an intellectual antidote to the growing secularism in American higher education. At the same time, it would counteract the founding, in Washington, of The Catholic University of America a few years before. The new university would be a capstone, graduate institution to serve all of Protestantism. It would draw on the educational resources of Washington to become a university of "national" importance without direct federal assistance or control. In 1892, the General Conference of the Methodist Episcopal Church voted to support the university, with the proviso that it raise five million dollars in endowment before opening. The fund raising challenge grew harder a year later with the onset of the economic "Panic of 1893." In addition to financial uncertainty, Hurst's efforts suffered from contradictory goals, grandiose building plans, competition from existing Methodist institutions, and confusion over efforts to create a federally-funded, national university in Washington. The American University's problems persisted through Hurst's death in 1903, and the lackluster tenure of his successor, Bishop Charles C. McCabe. The university opened in 1914, only after the General Conference withdrew its endowment requirement and Chancellor Franklin Hamilton dispensed with Hurst's unrealistic educational vision. Hamilton's modest program depended upon the resources and experts of the federal government, and operated as such until 1924, when the university admitted undergraduates for the first time. In spite of Hurst's idealistic vision, his support for coeducation, and the operation of the university as a graduate institution, the early history of The American University has been largely ignored by educational historians. This study is intended to remedy this longstanding oversight.
Angular asymmetries in the reactions pp \to dπ^+ηand pn \to dπ^0ηand a_0-f_0 mixing
Creators: name: Kudryavtsev, A. E.
name: Tarasov, V. E.
name: Haidenbauer, J.
name: Hanhart, C.
name: Speth, J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The reactions pp\to dπ^+ηand pn\to dπ^0ηare of special interest for investigating the a_0(980) (J^P=0^+) resonance in the process NN \to da_0 \to dπη. We study some aspects of those reactions within a general formalism and also in a concrete phenomenological model. In particular, it is shown that the presence of nonresonant (i.e. without excitation of the a_0 resonance) contributions to these reactions yields nonvanishing values for specific polarization observables, i.e. to effects like those generated by a_0-f_0 mixing. An experimental determination of these observables for the reaction pp\to dπ^+ηwould provide concrete information on the magnitude of those nonresonant contributions to πηproduction. We discuss also the possibility of extracting information about a_0-f_0 mixing from the reaction pn \to dπ^0ηwith polarized proton beam.
description: 14 pages, 3 figures
title: 01_2322
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
A multi-stage virtual screening of FDA-approved drugs reveals potential inhibitors of SARS-CoV-2 main protease
Creators: name: Mandour, Yasmine M.
name: Zlotos, Darius P.
name: Salem, M. Alaraby
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology

description: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Repurposing of approved pharmaceutical drugs for COVID-19 treatment represents an attractive approach to quickly identify promising drug candidates. SARS-CoV-2 main protease (Mpro) is responsible for the maturation of viral functional proteins making it a key antiviral target. Based on the recently revealed crystal structures of SARS-CoV-2 Mpro, we herein describe a multi-stage virtual screening protocol including pharmacophore screening, molecular docking and protein-ligand interaction fingerprints (PLIF) post-docking filtration for efficient enrichment of potent SARS-CoV-2 Mpro inhibitors. Potential hits, along with a cocrystallized control were further studied via molecular dynamics. A 150-ns production trajectory was followed by RMSD, free energy calculation, and H-bond analysis for each compound. The applied virtual screening protocol led to identification of five FDA-approved drugs with promising binding modes to key subsites of the substrate-binding pocket of SARS-CoV-2 Mpro. The identified compounds belong to different pharmaceutical classes, including several protease inhibitors, antineoplastic agents and a natural flavonoid. The drug candidates discovered in this study present a potential extension of the recently reported SARS-CoV-2 Mpro inhibitors that have been identified using other virtual screening protocols and may be repurposed for COVID-19 treatment.
Ilicales Bercht. & J.Presl.
Creators: name: Reveal, James L.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Plantae
Ilicales

description: Ilicales
 Bercht. & J.Presl, P ř ir. Rostlin: 226. January–April 1820 (Illicinae), predates Mart., Consp. Regn. Veg.: 26. September–October 1835—Ilicaceae Dumort. (1829).
description: Published as part of Reveal, James L., 2011, New ordinal names established by changes to the botanical code, pp. 42-44 in Phytotaxa 30 on page 43, DOI: 10.11646/phytotaxa.30.1.2, http://zenodo.org/record/4894455
Injection seeded, diode-pumped, short pulse neodymium:YAG ring laser for space based laser ranging
Creators: name: Coyle, Donald Barry
Publisher: name: American University
Year: 2023

description: In the near future, NASA plans to deploy LIDAR (Light Detection And Ranging) systems in space for the purpose of measuring geophysical quantities such as tectonic plate movement, crustal deformation near faults, and volcanic activity. Information on other quantities such as ice floes, cloud movement heights, and sea levels are also of interest. These measurements will require a spaceborne laser system which can operate unattended for extended periods of time and be able to make reliable sub-centimeter distance determinations from space. One system concept is the Geodynamic Laser Ranging System (GLRS) (Cohen et al. 1987). Optical pulses of 100 ps, or less, will be required from a Nd:YAG laser. The fundamental wavelength will provide altimetry information while the second and third harmonic frequencies will be generated to measure distances with high accuracy through two-color ranging techniques. Sub-100 ps pulses can be produced using either pulse pumped or continuous wave (cw) pumped mode-locked lasers. Shorter pulses are frequently achieved through cw pumping but the pulse energy is low, typically less than 10$\sp{-8}$ J. A method of achieving the pulse width of a cw mode-locked laser and pulse energy of a pulse pumped laser involves using regenerative amplification. The presented work covers one possible method of short pulse amplification. A pulsed Nd:YAG ring regenerative amplifier, pumped by laser diode-arrays and injection seeded by a 100 ps source, has been constructed. It was shown that high total optical gains can be achieved while holding the stringent alignment and timing specifications of regenerative amplification to a minimum. The construction of this laser/amplifier provided data on the behavior of 100 ps pulses when used as a temporal seed in a typical oscillator cavity with multiple optical surfaces.
Injection seeded, diode-pumped, short pulse neodymium:YAG ring laser for space based laser ranging
Creators: name: Coyle, Donald Barry
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 51
subject: Physical sciences
subject: FOS: Physical sciences
classificationCode: 5102
subject: Atomic, molecular and optical physics

description: In the near future, NASA plans to deploy LIDAR (Light Detection And Ranging) systems in space for the purpose of measuring geophysical quantities such as tectonic plate movement, crustal deformation near faults, and volcanic activity. Information on other quantities such as ice floes, cloud movement heights, and sea levels are also of interest. These measurements will require a spaceborne laser system which can operate unattended for extended periods of time and be able to make reliable sub-centimeter distance determinations from space. One system concept is the Geodynamic Laser Ranging System (GLRS) (Cohen et al. 1987). Optical pulses of 100 ps, or less, will be required from a Nd:YAG laser. The fundamental wavelength will provide altimetry information while the second and third harmonic frequencies will be generated to measure distances with high accuracy through two-color ranging techniques. Sub-100 ps pulses can be produced using either pulse pumped or continuous wave (cw) pumped mode-locked lasers. Shorter pulses are frequently achieved through cw pumping but the pulse energy is low, typically less than 10$\sp{-8}$ J. A method of achieving the pulse width of a cw mode-locked laser and pulse energy of a pulse pumped laser involves using regenerative amplification. The presented work covers one possible method of short pulse amplification. A pulsed Nd:YAG ring regenerative amplifier, pumped by laser diode-arrays and injection seeded by a 100 ps source, has been constructed. It was shown that high total optical gains can be achieved while holding the stringent alignment and timing specifications of regenerative amplification to a minimum. The construction of this laser/amplifier provided data on the behavior of 100 ps pulses when used as a temporal seed in a typical oscillator cavity with multiple optical surfaces.
Inflation -- a Comparative Study Amongst Different Modified Gravity Theories
Creators: name: Saha, Dalia
name: Sanyal, Abhik Kumar
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In the recent years, a host of modified gravity models have been proposed as alternatives to the dark energy. A quantum theory of gravity also requires to modify `General Theory of Relativity'. In the present article, we consider five different modified theories of gravity, and compare inflationary parameters with recent data sets released by two Planck collaboration teams. Our analysis reveals that the scalar-tensor theory of gravity is the best alternative.
description: 21 Pages, 0 figures
An analysis of the written policy and procedures on acquired immune deficiency syndrome of a sample of post-secondary, four-year institutions
Creators: name: DiBacco, Mallie Zidenah Rowe
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 39
subject: Education
classificationCode: 3903
subject: Education systems
classificationCode: 3904
subject: Specialist studies in education

description: This study examined the extent to which written policy and procedures on Acquired Immune Deficiency Syndrome (AIDS) of 137 post-secondary, four-year institutions complied with the American College Health Association's (ACHA) 13 guidelines on AIDS. These guidelines strive to assist officials in higher education in policy making on AIDS. The ACHA serves its membership through various educational programs. Through such activities, member institutions voluntarily shared their AIDS policies with the ACHA, which, while not approving or disapproving any in terms of compliance to its 13 guidelines, permitted the researcher access to all (137) on file at ACHA in August 1990. The policies, coded for anonymity, were examined by the researcher and a tenured university professor and rated according to a compliance continuum that ranged from 4.00 (full compliance) to 0.00 (non-compliance). The mean and mean ranking of the guidelines provided an indication of the priority placement according to institutional compliance. A t test was employed to assess differences in compliance between institutions by source of control (public versus private). The study also examined differences in institutional compliance according to enrollment and state-reported AIDS cases classification. Overall institutional compliance revealed that the sample institutions complied most fully with three guidelines requiring minimal institutional effort and expense: adoption of General/Flexible Policies, adherence to Confidentiality of Information, and creation of an Institutional Committee. Six guidelines necessitating greater institutional attention and commitment through possibly additional personnel expertise, medical services, and specific health and legal measures were found in lesser compliance: Medical Care, Safety Precautions, HIV Antibody Testing, Handicapping Conditions, Admissions, and Harassment. Source of control, enrollment, and state-reported AIDS cases classification appeared to have little correlation to institutional compliance. The study findings seem to warrant the conclusion that the 137 written institutional policy and procedures on AIDS reviewed fall short of meeting the ACHA's expectations outlined by the ACHA Task Force on AIDS' General Statement on Institutional Response to AIDS.
Sparse PCA on fixed-rank matrices
Creators: name: Del Pia, Alberto
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Discrete Mathematics (cs.DM)
subject: Optimization and Control (math.OC)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Sparse PCA is the optimization problem obtained from PCA by adding a sparsity constraint on the principal components. Sparse PCA is NP-hard and hard to approximate even in the single-component case. In this paper we settle the computational complexity of sparse PCA with respect to the rank of the covariance matrix. We show that, if the rank of the covariance matrix is a fixed value, then there is an algorithm that solves sparse PCA to global optimality, whose running time is polynomial in the number of features. We also prove a similar result for the version of sparse PCA which requires the principal components to have disjoint supports.
title: Correspondance avec Gina Kolata et John David - Pièce jointe 2
Creators: name: David, John R.
name: Kolata, Gina Bari (1948-....)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 2 pièces jointes : Jacques Leibowitch, et al., "Short cycles of antiretroviral drugs provide intermittent yet effective therapy : a pilot study in 48 patients with chronic HIV infection", extrait de The FASEB Journal, 26 janvier 2010 ; graphiques sur le traitement ICARRE.
description: Source: http://www.calames.abes.fr/pub/ms/Calames-2019311113234777