cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Phytophthora palmivora agente causal de la pudrición de fruto de papaya (Carica papaya) en Chiapas, México.
Creators: name: Rodríguez-Alvarado, Gerardo
name: Díaz-Celaya, Marlene
name: Grünwald, Niklaus J.
name: Fieland, Valerie
name: Garay-Serrano, Edith
name: Fernández-Pavía, Sylvia Patricia
Publisher: name: Biotecnología y Sustentabilidad
Year: 2020

description: México es el tercer productor a nivel mundial de papaya y uno de los principales países exportadores. Chiapas es el tercer estado productor a nivel nacional, después de Oaxaca y Colima. Phytophthora palmivora es uno de los patógenos que se ha reportado causando pudrición en frutos y raíces, y se considera una de las principales enfermedades de la papaya en el ámbito mundial. Durante 2017, se observaron frutos de papaya var. Maradol con síntomas de pudrición en huertas comerciales en Chiapas. El objetivo del trabajo fue identificar el agente causal de la pudrición en frutos de papaya var. Maradol, por lo que en agosto de 2017 se colectaron frutos con síntomas y muestras de suelo de un campo de cultivo en Frontera Hidalgo, Chiapas. Una vez procesadas las muestras, se obtuvieron 4 aislados en medio selectivo, estos se crecieron en medio V-8, y se caracterizaron morfológica y molecularmente al amplificar la región región ITS del ADN ribosomal con los oligonucleótidos ITS5 e ITS4. También se realizaron pruebas de patogenicidad, para lo cual se inocularon frutos de papaya con discos de micelio, incubándose a 25±1oC. Los aislados presentaron esporangios papilados, con pedicelos cortos, caducos, ovoides (28-38 x 40-53 µm), originados en esporangióforos ramificados en simpodios simples, clamidosporas globosas terminales (32-42 x 32-42.5 µm), anteridios anfíginos (8-13 x 10-14 µm) y oosporas pleróticas (25-35 x 26-36 µm). La secuencia obtenida mostró 100% de identidad y cobertura con P. palmivora. De acuerdo con las evidencias morfológicas, moleculares y de patogenicidad obtenidas, se determinó que P. palmivora es el agente causal de los síntomas de pudrición de fruto en papaya var. Maradol en Chiapas.
description: Biotecnología y Sustentabilidad, Vol. 5 Núm. 1 (2020): Biotecnología y Sustentabilidad 2020
Diversidad en suelo y antagonismo de actinobacterias contra Sclerotium rolfsii
Creators: name: Rodríguez-Guerra, Raúl
name: Reyes-Castillo, Francisco
name: Ledesma-Bravo, Bernardo
name: Calderón-Ruiz, Alberto
name: Armijo-Martínez, Luis Fernando
name: Ruiz-Amaro, Carlos Jesús
Publisher: name: Biotecnología y Sustentabilidad
Year: 2020

description: Actinobacterias aisladas de suelo cultivado con melón y de suelo cercano no cultivado fueron caracterizadas por morfotipo y evaluadas por su actividad antagónica contra Colletotrichum musae, Moniliophthora roreri, Phytophthora capsici y Sclerotium rolfsii. Cincuenta morfotipos diferentes fueron identificados entre ambos suelos, 20 exclusivos de suelo cultivado, 24 de suelo nativo cercano no cultivado y cinco fueron comunes en ambos. El índice de diversidad para el suelo cultivado fue de 3.76, mientras que para el no cultivado fue de 3.46 lo que demuestra que la diversidad es muy similar entre ambos suelos, pero con escasos morfotipos similares. Los morfotipos obtenidos fueron confrontados en un escrutinio sin repeticiones contra los fitopatógenos e inhibieron en promedio su crecimiento más del 95 %. Dos morfotipos (M-14 y M-18) fueron seleccionados para determinar su capacidad antagónica contra S. rolfsii mediante pruebas de confrontación dual, fungicidad/fungistasis y producción de compuestos volátiles. Ambos morfotipos mostraron 100% de inhibición del crecimiento micelial del fitopatógeno, y exposiciones de 4 y 8 h en confrontación con las actinobacterias mostraron un efecto fungistático y fungicida respectivamente. Los resultados demostraron que los morfotipos tienen una elevada capacidad antagónica, por lo pueden ser considerados potenciales agentes de biocontrol contra S. rolfsii.
description: Biotecnología y Sustentabilidad, Vol. 5 Núm. 1 (2020): Biotecnología y Sustentabilidad 2020
Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis
Creators: name: Day, Zoe
name: Mayfosh, Alyce
name: Giel, Marie-Claire
name: Hong, Yuning
name: Williams, Scott
name: Santavanond, Jascinta P
name: Rau, Thomas F
name: Poon, Ivan K
name: Hulett, Mark
Publisher: name: La Trobe
Year: 2022

description: Undecylenic acid, a monounsaturated fatty acid, is currently in clinical use as a topical antifungal agent, however the potential for therapeutic application in other disease settings has not been investigated. In this study, we describe a novel platform for the solubilization of fatty acids using amino acids and utilize this approach to define a tumoricidal activity and underlying mechanism for undecylenic acid. We examined a novel formulation of undecylenic acid compounded with L-Arginine, called GS-1, that induced concentration-dependent tumor cell death, with undecylenic acid being the cytotoxic component. Further investigation revealed that GS-1-mediated cell death was caspase-dependent with a reduction in mitochondrial membrane potential, suggesting a pro-apoptotic mechanism of action. Additionally, GS-1 was found to localize intracellularly to lipid droplets. In contrast to previous studies where lipid droplets have been shown to be protective against fatty acid-induced cell death, we showed that lipid droplets could not protect against GS-1-induced cytotoxicity. We also found a role for Fatty Acid Transport Protein 2 (FATP2) in the uptake of this compound. Collectively, this study demonstrates that GS-1 has effective pro-apoptotic antitumor activity in vitro and, together with the novel platform of fatty acid solubilization, contributes to the re-emerging field of fatty acids as potential anti-cancer therapeutics.
Inhibición de Fusarium solani por bacterias de la filósfera y rizósfera de árboles del bosque mesófilo de montaña
Creators: name: Reverchon, Frédérique
name: Escudero-Osorio, Yonatan S.
name: Morteo-Zavaleta, Jessica
name: Guevara-Avendaño, Edgar
name: Ramírez-Vázquez, Mónica
Publisher: name: Biotecnología y Sustentabilidad
Year: 2020

description: El potencial biotecnológico de las bacterias asociadas a árboles silvestres ha sido escasamente investigado. Por lo tanto, el objetivo del presente estudio fue evaluar la actividad antifúngica de bacterias aisladas a partir de muestras de filósfera y de rizósfera de cuatro especies de árboles de un bosque mesófilo de montaña, para así ampliar nuestra búsqueda de agentes potenciales de control biológico del hongo fitopatógeno Fusarium solani. Se evaluaron 55 aislados bacterianos en ensayos de antagonismo in vitro contra F. solani; 15 aislados inhibieron de manera significativa el crecimiento micelial del hongo, con porcentajes de inhibición de hasta 33%. A través de la secuenciación del gen bacteriano 16S rADN, se identificaron estos aislados como pertenecientes al filo Actinobacteria y a los géneros Bacillus, Staphylococcus y Pseudomonas. Posteriormente, se seleccionaron tres aislados con porcentajes de inhibición superiores al 25% para estudiar su efecto sobre las hifas de F. solani mediante microscopía confocal. Las imágenes obtenidas confirmaron la actividad antifúngica de estos tres aislados bacterianos ya que se observó el engrosamiento zonado de la pared celular de las hifas, así como intervalos entre septos más cortos. El aislado Rhodococcus sp. PsRi3-003, obtenido de la rizósfera de Persea schiedeana, es el candidato más promisorio para la realización de pruebas posteriores, dado que presentó la inhibición más fuerte de F. solani y la capacidad de producir alteraciones morfológicas en las hifas. Dichas pruebas deberán incluir ensayos de invernadero para confirmar su actividad in planta y la evaluación de posibles propiedades promotoras de crecimiento vegetal, para corroborar su potencial como agente de control biológico.
description: Biotecnología y Sustentabilidad, Vol. 5 Núm. 1 (2020): Biotecnología y Sustentabilidad 2020
Cage hydrocarbons as linkers in dimeric drug design: Case studies with trimethoprim and tedizolid
Creators: name: Vujcic, Biljana
name: Wyllie, Jessica
name: Tania, Tania
name: Burns, J
name: White, Keith
name: Cromwell, S
name: Lupton, DW
name: Dutton, Jason
name: Soares-da-Costa, Tatiana
name: Houston, SD
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3404
subject: Medicinal and biomolecular chemistry
classificationCode: 3405
subject: Organic chemistry

description: No description supplied
Caracterización funcional de hongos aislados de suelo por su capacidad antagónica contra Macrophomina phaseolina
Creators: name: Almeyda-León, Isidro Humberto
name: Rodríguez-Guerra, Raúl
name: López-Arroyo, J. Isabel
name: Rodríguez-Villarreal, Raúl Asael
name: Robledo-Leal, Efrén Ricardo
name: Armijo-Martínez, Luis Fernando
Publisher: name: Biotecnología y Sustentabilidad
Year: 2020

description: Hongos aislados de suelos cultivados con sorgo, soya, melón y chile, así como de suelos nativos no cultivados cercanos a las parcelas cultivadas, se caracterizaron funcionalmente por su actividad antagónica por antibiosis contra Macrophomina phaseolina, causante de la enfermedad conocida como pudrición carbonosa de plantas cultivadas. De un total de 312 aislados obtenidos entre ambos tipos de suelo, se identificaron 212 morfotipos, 195 fueron distintos y 17 comunes para ambos tipos de suelo. La cantidad de morfotipos identificados fue similar tanto en suelos cultivados como en suelos nativos cercanos (105 y 107, respectivamente). La diversidad de morfotipos en cada suelo fue relativamente elevada con base en el índice de diversidad de Shannon y Wiener. Ciento sesenta y siete morfotipos fueron evaluados en un escrutinio sin repeticiones contra cepas del patógeno aisladas de soya, melón, chile y frijol. Quince morfotipos que mostraron más del 70 % de inhibición se evaluaron por confrontación dual contra una cepa de Macrophomina aislada de sorgo, bajo un diseño experimental. Tres morfotipos causaron una inhibición por antibiosis de la cepa del fitopatógeno del sorgo mayor al 60%. De estos morfotipos dos fueron identificados al nivel de género como Aspergillus y uno como Penicillium. Este estudio muestra la ocurrencia de cepas de hongos con importante actividad funcional antagónica contra Macrophomina phaseolina.
description: Biotecnología y Sustentabilidad, Vol. 5 Núm. 1 (2020): Biotecnología y Sustentabilidad 2020
A Comparative Study of the Performance of Selected DSP Based PWM Methods
Creators: name: Brock, Stefan
Publisher: name: figshare
Year: 2013
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences
subject: Computer Engineering

description: In this paper a practical implementation of space vector modulation in digital signal processor is presented. The results of experimental investigation are shown. The selected method is compared with hysteresis current controller
Comparison between a targeted exercise program and a sham intervention on gluteal muscle activity in people with hip osteoarthritis: Analysis of secondary outcomes from a randomised clinical trial
Creators: name: Rostron, Zachary
name: Zacharias, Anita
name: Semciw, Adam
name: Kingsley, Michael
name: Pizzari, Tania
name: Woodley, Stephanie J
name: Green, Rodney
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 4003
subject: Biomedical engineering
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 4207
subject: Sports science and exercise

description: Background: People with hip osteoarthritis (OA) typically display altered gluteus minimus (GMin) and gluteus medius (GMed) activity during gait, in addition to reduced walking speed and stride length. It is unknown if current rehabilitation programs address changes in gluteal muscle activity in people with hip OA. 
Research question: Can a targeted gluteal intervention restore normal gluteal muscle segment activity during gait in people with hip OA? 
Methods: This study presents secondary outcomes from a multi-site, double-blinded clinical trial in which participants with radiologically confirmed mild-moderate hip OA were randomised into a targeted gluteal or sham intervention for 12-weeks following baseline testing. Electromyography (EMG) outcomes were only conducted at a single site and data were collected from 22 participants. Intramuscular electrodes were inserted into two segments of GMin (anterior, posterior) and three segments of GMed (anterior, middle, posterior) to record average amplitude, peak amplitude and time to peak (TTP) during the first 60 % of the gait cycle (stance phase) at baseline and post-intervention. 
Results: Following the targeted gluteal intervention, posterior GMin displayed a decrease in average (P = 0.032, ES=1.04) and peak (P = 0.017, ES=1.17) muscle activity during late stance phase with a shift to an earlier TTP (P = 0.034, ES=1.02). There were no further significant changes between groups for other outcome measures. Similar trends for an earlier TTP were observed for the posterior segment of GMed following the targeted intervention (P = 0.095, ES=0.87). The earlier TTP in the posterior segments of both GMin and GMed post-intervention resembled patterns observed in a healthy young population. 
Significance: A targeted gluteal intervention can positively impact activity in posterior GMin during gait in people with hip OA when compared to a sham intervention.
A Robust Artificial Intelligence Approach with Explainability for Measurement and Verification of Energy Efficient Infrastructure for Net Zero Carbon Emissions
Creators: name: Moraliyage, Harsha Kumara
name: Dahanayake, S
name: De Silva, Daswin
name: Mills, Nishan
name: Rathnayaka Mudiyanselage, Prabod Manuranga
name: Nguyen, Su
name: Alahakoon, Damminda
name: Jennings, A
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 4008
subject: Electrical engineering
classificationCode: 4009
subject: Electronics, sensors and digital hardware
classificationCode: 46
subject: Information and computing sciences
classificationCode: 4605
subject: Data management and data science
classificationCode: 4606
subject: Distributed computing and systems software

description: Rapid urbanization across the world has led to an exponential increase in demand for utilities, electricity, gas and water. The building infrastructure sector is one of the largest global consumers of electricity and thereby one of the largest emitters of greenhouse gas emissions. Reducing building energy consumption directly contributes to achieving energy sustainability, emissions reduction, and addressing the challenges of a warming planet, while also supporting the rapid urbanization of human society. Energy Conservation Measures (ECM) that are digitalized using advanced sensor technologies are a formal approach that is widely adopted to reduce the energy consumption of building infrastructure. Measurement and Verification (M&V) protocols are a repeatable and transparent methodology to evaluate and formally report on energy savings. As savings cannot be directly measured, they are determined by comparing pre-retrofit and post-retrofit usage of an ECM initiative. Given the computational nature of M&V, artificial intelligence (AI) algorithms can be leveraged to improve the accuracy, efficiency, and consistency of M&V protocols. However, AI has been limited to a singular performance metric based on default parameters in recent M&V research. In this paper, we address this gap by proposing a comprehensive AI approach for M&V protocols in energy-efficient infrastructure. The novelty of the framework lies in its use of all relevant data (pre and post-ECM) to build robust and explainable predictive AI models for energy savings estimation. The framework was implemented and evaluated in a multi-campus tertiary education institution setting, comprising 200 buildings of diverse sensor technologies and operational functions. The results of this empirical evaluation confirm the validity and contribution of the proposed framework for robust and explainable M&V for energy-efficient building infrastructure and net zero carbon emissions.
Protected health information breaches on GitHub
Creators: name: Evans, Perry
name: Deanne, Taylor
Publisher: name: Zenodo
Year: 2020
Subjects: GitHub
PHI

description: Medical scientists are encouraged to use GitHub for software development, but without training, they might leak protected health information (PHI) by inadvertently including data in what should be software repositories. During the fall of 2016, we attempted to identify obvious breaches of PHI on GitHub as part of an ongoing interest in patient privacy. Searching GitHub for keywords patient, dob, and ssn uncovered hundreds of repositories, which were further scanned for sensitive information (names, organizations, phone numbers, street addresses, credit cards, IPs, SSNs, and emails) using Python's common regex module and the Stanford Natural Language Toolkit. Manual investigation of the results uncovered three repositories that exposed patient information. A popular health care provider exposed approximately 4000 patient names. On Dec 1, we were able to track down the healthcare provider from both the repository name and doctor names in the repository files. We contacted the organization and those repositories were taken down within the day of contact. A health collection agency’s repository led to the exposure of social security numbers, dates of birth, home addresses, email addresses, and insurance and billing information of roughly 30,000 patients. After we contacted the repository owner, the data and the repository were removed from GitHub some six months after the data had first been exposed. A crisis center’s long-term breach of PHI was discovered in August 2016, and from the repository dates, it had been up for at least three years. The original repository managed the medical records application developed for the crisis center. We contacted that organization and the repository was taken down within a few days. A contractor for a health insurance wellness program leaked some patient data with names, social security numbers, addresses, and health measures such as blood pressure, etc. This organization was contacted by our hospital compliance office and the GitHub repository was removed. Our talk will cover the discovery of these PHI breaches, and how we handled them with GitHub, our compliance office, and the organizations involved.
Water and the biology of *prions* and plaques
Creators: name: Steel, Graham
Publisher: name: figshare
Year: 2013
Subjects: Cell Biology

description: This is an attempt to account for the insolubility and/or aggregation of prions and plaques in terms of a model of water consisting of an equilibrium between high density and low density microdomains. Hydrophobic molecules, including proteins,
accumulate selectively into stable populations, enriched in high density water, at
charged sites on biopolymers. In enriched high density water, proteins are probably
partially unfolded and may precipitate out when released. All extracellular matrices
contain such charged polymers. Prions, which have been shown to accumulate in soils
and clays containing silicates and aluminates also probably accumulate in extracellular matrices.
Nanocrystalline carbon film electrodes generated and patterned by UV-laser ablation of polystyrene
Creators: name: Girault, Hubert
Publisher: name: figshare
Year: 2013
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: A carbon conductive film consisting of nanometer sized domains has been patterned by scanning photoablation of polystyrene. The film formation involves the photoablation of a highly insulating polymer, and the redeposition of conductive carbon fragments. This film has been investigated by scanning electron microscopy, atomic force microscopy, microRaman spectroscopy, electrical conductivity and standard electrochemical measurements. Film deposition under different gas flow conditions has revealed major differences in the electrical and electrochemical properties of the material. Cyclic voltammetry and double layer capacitance measurements have indicated the formation of a conductive layer with a high specific area when generated in ambient atmosphere. Inert atmospheres like nitrogen and argon lead to conducting films with low double layer capacitance values (10 mu F cm(-2)), whereas an air atmosphere leads to conducting films with supercapacitance values (5 mF cm(-2)). This large difference in capacitances is discussed in terms of the photochemical effects of the ambient atmosphere during the polymer treatment.
Photoinduced electron transfer at liquid/liquid interfaces - Part II. A study of the electron transfer and recombination dynamics by intensity modulated photocurrent spectroscopy (IMPS)
Creators: name: Girault, Hubert
Publisher: name: figshare
Year: 2013
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The dynamics of photoresponses associated with heterogeneous quenching of zinc tetrakis(carboxphenyl)porphyrin (ZnTPPC) and ferrocene derivatives at the water/1,2-dichloroethane interface were studied by intensity modulated photocurrent spectroscopy (IMPS). The contribution arising from the electron injection, recombination-product separation competition and the attenuation associated with the uncompensated resistance and interfacial capacitance (RC) time constant of the cell were deconvoluted in the frequency domain. The flux of electron injection was described in terms of a competition between the relaxation of the porphyrin excited state and the electron transfer step. Experimental results in the presence of ferrocene and diferrocenylethane confirmed that as the Galvani potential difference is increased, the phenomenological electron transfer rate constant increases and the ZnTPPC coverage at the liquid/liquid junction decreases. Furthermore, the recombination rate constant decreases with increasing potentials, while the product separation rate constant did not show a clear potential dependence. Photocurrent studies were extended to the electron donors dimethylferrocene and trianisylamine, as well as to the electron acceptor tetracyanoquinodimethane. The results obtained clearly indicate that the Gibbs energy of activation for the charge transfer process is affected by the Galvani potential difference. It is suggested that the electron transfer dynamics are dependent on the local electric field generation by the specifically adsorbed ZnTPPC. The general expressions for the frequency dependent photocurrents at liquid/liquid interfaces are also introduced.
title: Relationship of Shoe Wetness to Mechanical Performance
Creators: name: Crawford, Sara
Publisher: name: University of Nevada, Las Vegas
Year: 2021

description: The purpose of this study was to mechanically impact test shoes that underwent both saturation and repetitive loading protocols to determine if these interventions affected the impact absorption and energy return properties of a shoe. Six pairs of the same make and model of shoe were divided into Control and Experimental Groups and tested on an impact machine before and after undergoing a protocol. The repetitive load protocol involved subjecting the shoes to impacts commensurate with a 5 km race. The water saturation protocol involved soaking the shoes until reaching their maximum saturation. The Control shoes underwent initial testing and post-repetitive load testing. The Experimental shoes underwent initial testing, post-water saturation testing, and post-repetitive load testing while water saturated. Dependent Variables (peak force, peak acceleration, maximum displacement, dwell time, energy absorption, hysteresis energy ratio) were compared using a two-way mixed Analysis of Variance (ANOVA) for the Independent Variables of shoe group (two levels – control and experimental) and repetitive loading (two levels – initial and post repetitive loading). The same Dependent Variables were compared using a one-way repeated measures ANOVA for the Independent Variable of time (initial, post-saturation, post-repetitive loading) in the Experimental Group. It was determined that energy return (energy absorption, hysteresis energy ratio) was influenced by water saturation (p < 0.05) but not by repetitive loading (p > 0.05) or the interaction of water saturation and repetitive loading (p > 0.05). Impact protection was not influenced by any of the conditions. Runners should be aware that wet shoes may be harder to run in and make efforts to avoid saturation.
Position-Specific Running and Technical Demands During Male Elite-Junior and Elite-Senior Australian Rules Football Match-Play
Creators: name: Jennings, Jacob
name: Staka, Zorana
name: Wundersitz, Daniel
name: Sullivan, Courtney
name: Cousins, Stephen
name: Custovic, Edhem
name: Kingsley, Michael
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 3208
subject: Medical physiology
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4207
subject: Sports science and exercise

description: No description supplied
title: 3-D Comparison of Upper Airway Volume, Shape, and Airway Related Features in Patients of Different Vertical Skeletal Classification With or Without Excessive Daytime Sleepiness
Creators: name: Dao, Minhquan
Publisher: name: University of Nevada, Las Vegas
Year: 2021

description: Objectives: To compare the airway volume, the airway minimum cross-section area, the airway shape, and the airway related features to vertical growth pattern classifications in subjects with or without excessive daytime sleepiness (EDS). Introduction: The awareness, diagnosis, and management of sleep disordered breathing disorders has grown exponentially in the dental clinical setting. Excessive daytime sleepiness is a potential indicator for OSA. CBCT imaging of the airway and airway related features in patients with or without EDS may provide clinicians with a potential way to screen and detect SDB disorders in our everyday patients.

Materials and Methods: 282 patients from the University of Nevada Las Vegas Orthodontic Clinic (18+ in age, 101 males, 181 females) were classified into three groups based on their vertical skeletal patterns: Hypodivergent (79), normodivergent (143), hyperdivergent (60). Each patient was categorized as high or low risk for EDS based on their responses to the Epworth Sleepiness Scale. CBCT was used to compare the airway volume, minimum cross-section (MCSA), MCSA airway shape, and the airway related skeletal features of each patient.

Results: There were significant differences between the measured minimum cross-sectional area of the airway between patients diagnosed with hyperdivergent and hypodivergent vertical skeletal growth pattern (p

Conclusions: There are significant differences between vertical skeletal classification and minimum cross-sectional airway area and hyoid to mandibular plane measurements. Total airway volume has a positive relationship to the hyoid to mandibular plane measurement. Sleepiness classified by the Epworth Sleepiness Scale was not a significant predictor in airway volume, shape or airway related skeletal features.
Effects of charge and intramolecular structure on the lipophilicity of nitrophenols
Creators: name: Girault, Hubert
Publisher: name: figshare
Year: 2013
Subjects: Pharmacology

description: The lipophilicity of a series of phenolic compounds was studied in the 1,2-dichloroethane (1,2- DCE)/water system. Cyclic voltammetry at the ITIES was used to study the transfer characteristics of the charged species, and their partition coefficient was deduced from their formal transfer potential. For the neutral species, log PDCE values were measured by a two-phase pH-metric method. The results are compared to those previously obtained in octanol/water and by linear solvation energy relationships (LSER) in the two solvent systems. It is shown that nitrophenols with intramolecular H-bonding deviate from the solvatochromic equation for the 1,2-DCE/water system, and discrepancies between both approaches are discussed on the basis of conformational and steric effects. When charged however, all the species have approximately the same partition coefficients because the effect of the intramolecular H-bond disappears and the differences in measured lipophilicity arise from the variation of the intramolecular charge delocalization due to resonance equilibria. Some biological implications of these properties are discussed.
Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function
Creators: name: Hor, Lilian
name: Pilapitiya, Pilapitiye Herath
name: McKenna, James
name: Panjikar, S
name: Anderson, Marilyn
name: Desvaux, M
name: Paxman, Jason
name: Heras, Begona
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology

description: Autotransporters (ATs) are a large family of bacterial secreted and outer membrane proteins that encompass a wide range of enzymatic activities frequently associated with pathogenic phenotypes. We present the structural and functional characterisation of a subtilase autotransporter, Ssp, from the opportunistic pathogen Serratia marcescens. Although the structures of subtilases have been well documented, this subtilisin-like protein is associated with a 248 residue β-helix and itself includes three finger-like protrusions around its active site involved in substrate interactions. We further reveal that the activity of the subtilase AT is required for entry into epithelial cells as well as causing cellular toxicity. The Ssp structure not only provides details about the subtilase ATs, but also reveals a common framework and function to more distantly related ATs. As such these findings also represent a significant step forward toward understanding the molecular mechanisms underlying the functional divergence in the large AT superfamily.
CYCLIC VOLTAMMETRY FOR ELECTRON-TRANSFER REACTIONS AT LIQUID-LIQUID INTERFACES
Creators: name: Girault, Hubert
Publisher: name: figshare
Year: 2013
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Theory for cyclic voltammetry for heterogeneous electron transfer reactions at iquid-liquid interfaces
Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function
Creators: name: Hor, Lilian
name: Pilapitiya, A
name: McKenna, James
name: Panjikar, S
name: Anderson, Marilyn
name: Desvaux, M
name: Paxman, Jason
name: Heras, Begona
Publisher: name: La Trobe
Year: 2023

description: Autotransporters (ATs) are a large family of bacterial secreted and outer membrane proteins that encompass a wide range of enzymatic activities frequently associated with pathogenic phenotypes. We present the structural and functional characterisation of a subtilase autotransporter, Ssp, from the opportunistic pathogen Serratia marcescens. Although the structures of subtilases have been well documented, this subtilisin-like protein is associated with a 248 residue β-helix and itself includes three finger-like protrusions around its active site involved in substrate interactions. We further reveal that the activity of the subtilase AT is required for entry into epithelial cells as well as causing cellular toxicity. The Ssp structure not only provides details about the subtilase ATs, but also reveals a common framework and function to more distantly related ATs. As such these findings also represent a significant step forward toward understanding the molecular mechanisms underlying the functional divergence in the large AT superfamily.
AMPEROMETRIC STUDY OF IMMUNO-ION-SELECTIVE ELECTRODE RESPONSES USING BIOTIN-AZA-CROWN-6 IONOPHORE
Creators: name: Girault, Hubert
Publisher: name: figshare
Year: 2013
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The liquid-liquid electrochemistry of N-biotin-1-monoaza-crown-6 (BMAZC6) for the assisted transfer of potassium has been studied across the 1,2-dichloroethane-water interface by cyclic voltammetry. A model of the mechanism of the assisted K+ transfer by BMAZC6 is proposed. The influence of avidin in the aqueous phase on the assisted transfer of potassium is discussed when BMAZC6 is present in either the aqueous or the 1,2-dichloroethane phase. The mechanism of the interaction of avidin with the BMAZC6 is discussed. This assisted ion-transfer method is useful for the analytical determination of avidin down to 5 X 10(-7) M by differential pulse voltammetry.
Let's talk about sex (and gender) after ACL injury: A systematic review and meta-analysis of self-reported activity and knee-related outcomes
Creators: name: Bruder, Andrea
name: Culvenor, Adam
name: King, Matthew
name: Haberfield, Melissa
name: Roughead, Eliza
name: Mastwyk, John
name: Kemp, Joanne
name: Ferraz Pazzinatto, Marcella
name: West, Thomas
name: Coburn, Sally
name: Cowan, Sallie
name: Ezzat, Allison
name: To, Laura
name: Chilman, Karina
name: Couch, Jamon
name: Whittaker, JL
name: Crossley, Kay
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4207
subject: Sports science and exercise
classificationCode: 5201
subject: Applied and developmental psychology

description: No description supplied
Improving microRNA target prediction by performance-based algorithm combination
Creators: name: Caballero, Ignacio Sanchez
Publisher: name: figshare
Year: 2013
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: MicroRNAs have been at the center stage of the biomedical community for more than a decade now, after a team of scientists working at Harvard University in Cam- bridge discovered their vital role in the regulation of gene expression [1]. Since then, the use of bioinformatic tools has become a major accelerator in our understanding of microRNA function. Many algorithms have been created to predict where mi- croRNAs are encoded, as well as what genes they regulate [2–10]. Unfortunately, due to the popularity of the field, it is not always clear which of the available computa- tional methods is best suited for determining which mRNA transcripts are regulated by which microRNAs. We propose a straightforward method to combine the tens of currently available prediction algorithms, and assign them a credibility measure based on their previous performance to simplify the task of experimental validation.
Effects of Audit Specialization on Audit Planning, Audit Quality and Audit Performance: A Comparative Study of Certified Public Accountants and Tax Auditors in Thailand
Creators: name: Kornchai Phornlaphatrachakorn
Publisher: name: คณะพาณิชยศาสตร์และการบัญชี มหาวิทยาลัยธรรมศาสตร์
Year: 2020
Subjects: Audit Specialization
Audit Planning
Audit Quality
Audit Performance

description: วารสารวิชาชีพบัญชี JAP, 16, 49 (มีนาคม 63), 23
title: The Frontier of the Labor Movement: Latinas and the Longest Strike in Twentieth-Century Las Vegas
Creators: name: Estrada Calderón, Maribel
Publisher: name: University of Nevada, Las Vegas
Year: 2021

description: After the mid-twentieth century, the American labor movement began to decline. Across the U.S., Union memberships and the rate of work stoppages decreased. In the hospitality-industry-driven city of Las Vegas, Nevada, however, the Culinary Workers Union Local 226 more than doubled its membership. In 1989, the Elardi family purchased the Frontier Hotel and Casino and began to eliminate workers’ benefits. Led by the Culinary Union, workers went on strike on September 21, 1991, beginning one of the longest strikes in twentieth-century Las Vegas. Latina workers played critical roles in organizing and maintaining this successful, six-year-long battle against the Elardis. Positioning Latina workers’ oral histories at the center of this analysis, I trace the course of the dispute from 1989, when the Elardis purchased the Frontier, to 1998, when the strike ended after the Elardis sold the hotel. To reveal how and why Latinas participated in this strike, this project focuses on Latina workers’ immigration experiences, the familial bonds workers forged with one another, and the women who led the strike.
The Widening Gap between the Digital Capability of the Care Workforce and Technology-Enabled Healthcare Delivery: A Nursing and Allied Health Analysis
Creators: name: Morris, Meg
name: Brusco, Natasha
name: Jones, Jeffrey
name: Taylor, Nicholas
name: East, Christine
name: Semciw, Adam
name: Edvardsson, Kristina
name: Thwaites, Claire
name: Bourke, Sharon
name: Raza Khan, Urooj
name: Fowler-Davis, S
name: Oldenburg, Brian
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 4203
subject: Health services and systems
classificationCode: 4205
subject: Nursing

description: There is a need to ensure that healthcare organisations enable their workforces to use digital methods in service delivery. This study aimed to evaluate the current level of digital understanding and ability in nursing, midwifery, and allied health workforces and identify some of the training requirements to improve digital literacy in these health professionals. Representatives from eight healthcare organizations in Victoria, Australia participated in focus groups. Three digital frameworks informed the focus group topic guide that sought to examine the barriers and enablers to adopting digital healthcare along with training requirements to improve digital literacy. Twenty-three participants self-rated digital knowledge and skills using Likert scales and attended the focus groups. Mid-range scores were given for digital ability in nursing, midwifery, and allied health professionals. Focus group participants expressed concern over the gap between their organizations’ adoption of digital methods relative to their digital ability, and there were concerns about cyber security. Participants also saw a need for the inclusion of consumers in digital design. Given the widening gap between digital innovation and health workforce digital capability, there is a need to accelerate digital literacy by rapidly deploying education and training and policies and procedures for digital service delivery.
การบัญชีสำหรับหุ้นกู้อนุพันธ์ภายใต้ TFRS 9
Creators: name: สมชาย สุภัทรกุล
Publisher: name: คณะพาณิชยศาสตร์และการบัญชี มหาวิทยาลัยธรรมศาสตร์
Year: 2020
Subjects: หุ้นกู้อนุพันธ์
อนุพันธ์แฝง
สินทรัพย์ทางการเงิน
หนี้สินทางการเงิน

description: วารสารวิชาชีพบัญชี JAP, 16, 49 (มีนาคม 63), 50
Consecuencias da dependencia na almacenaxe electrónica para a preservación do coñecemento, legado e cultura humanos
Creators: name: Castro de Diego, Javier
name: Náñez Chierroni, Manuel
Publisher: name: Zenodo
Year: 2024

description: • Historia da conservación do coñecemento

• Ubicación física do coñecemento

• Depósito legal

• Ubicación física do coñecemento en dixital

• Vulnerabilidades inmediatas (ex. OVH)

• Vulnerabilidades catastróficas

• Protección contra as vulnerabilidades

• Plan B en caso de catástrofe

• Consecuencias da perda total (antimemes e memes)

• Regla 3-2-1 e a fiabilidade da nube (ex. MEGA)

• Situación no futuro, evolución

• Redes P2P e Torrent
title: Philosophical Reflection: Significance of Honesty in Trade
Creators: name: :None
Publisher: name: Springer Nature
Year: 2023
Subjects: subject: 200
subject: 330

description: This article talks about the concept of Fair Trade, overcoming the limitations imposed by the dominant Western discourse. In the Islamic tradition, there is a profound directive against the consumption of wealth acquired through falsehood, emphasising the avoidance of unjust, vain acquisition.
description: In diesem Artikel geht es um das Konzept des fairen Handels und darum, die Beschränkungen zu überwinden, die der vorherrschende westliche Diskurs auferlegt. In der islamischen Tradition gibt es eine tiefgreifende Anweisung gegen den Verbrauch durch Unwahrheit erworbenen Reichtums und die Betonung der Vermeidung ungerechten, eitlen Erwerbs.
Parent-Child Interactions May Help to Explain Relations Between Parent Characteristics and Clinically Observed Child Autistic Behaviours
Creators: name: Loncarevic, Antonina
name: Maybery, Murray T
name: Barbaro, Josephine
name: Dissanayake, Cheryl
name: Green, Jonathan
name: Hudry, Kristelle
name: Iacono, Teresa
name: Slonims, Vicky
name: Varcin, Kandice J
name: Wan, Ming Wai
name: Wray, John
name: Whitehouse, Andrew JO
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 39
subject: Education
classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5203
subject: Clinical and health psychology
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: The importance of supporting parent-child interactions has been noted in the context of prodromal autism, but little consideration has been given to the possible contributing role of parental characteristics, such as psychological distress. This cross-sectional study tested models in which parent-child interaction variables mediated relations between parent characteristics and child autistic behaviour in a sample of families whose infant demonstrated early signs of autism (N = 103). The findings suggest that associations between parent characteristics (psychological distress; aloofness) and child autistic behaviours may be mediated by the child’s inattentiveness or negative affect during interactions. These findings have important implications in developing and implementing interventions in infancy which target the synchrony of parent-child interaction with the goal to support children’s social communication development.
Human Capital and the strange spaces of economic statistics
Creators: name: Jenkins, Matt
Publisher: name: figshare
Year: 2013
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: Geography
subject: Economics

description: This is a short conference paper, outlining a problematic of the ONS' 'Human Capital' statistic. It poses the question of how the statistic deals with issues of space.
Vía sacra de Jerez: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2024
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Vía sacra de Jerez: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2021
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2022), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Vía sacra de Jerez: Digital edition
Creators: name: Leblanc Elina
Publisher: name: Zenodo
Year: 2022
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Workforce training in family therapy and systemic practices: An evaluation framework and case study
Creators: name: Hameed, Mohajer
name: McIntosh, Jennifer
name: McLean, Sian
name: Vuong, An Thanh
name: Welsh, Ellen
name: O'Hanlon, Brendan
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 4409
subject: Social work
classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5201
subject: Applied and developmental psychology
classificationCode: 5203
subject: Clinical and health psychology

description: Abstract: Internationally, while the interdisciplinary field of family therapy  and  systemic  practices  is  well  established and evidence  for  therapeutic  impact  is  advanced,  evaluation  of training  and  measurement  of  its  impact  lags  behind.  This paper  addresses  this  gap,  utilising  a  single  case  study  at the  Bouverie  Centre,  the  largest  family  therapy  and workforce development  service  in  Australia.  We  describe  (a)  the  scope of  workforce  training  and implementation at the Centre, (b) the development of our training  research  and  evaluation framework, and  (c)  standardised data collection methodology, including a pre-post training reflective survey. Collectively, this work comprises our current evaluation framework through which we will subsequently ex-amine training impact. Future research and practice recommen-dations are offered to address challenges to workforce training evaluation and progress efficacy of family therapy training.
Workforce training in family therapy and systemic practices: An evaluation framework and case study
Creators: name: Hameed, Mohajer
name: McIntosh, Jennifer
name: McLean, Sian
name: Vuong, An
name: Welsh, Ellen
name: O'Hanlon, Brendan
Publisher: name: La Trobe
Year: 2023

description: Abstract: Internationally, while the interdisciplinary field of family therapy  and  systemic  practices  is  well  established and evidence  for  therapeutic  impact  is  advanced,  evaluation  of training  and  measurement  of  its  impact  lags  behind.  This paper  addresses  this  gap,  utilising  a  single  case  study  at the  Bouverie  Centre,  the  largest  family  therapy  and workforce development  service  in  Australia.  We  describe  (a)  the  scope of  workforce  training  and implementation at the Centre, (b) the development of our training  research  and  evaluation framework, and  (c)  standardised data collection methodology, including a pre-post training reflective survey. Collectively, this work comprises our current evaluation framework through which we will subsequently ex-amine training impact. Future research and practice recommen-dations are offered to address challenges to workforce training evaluation and progress efficacy of family therapy training.