cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Chitinolytic microbes confer Meloidogyne incognita resistance and augment secondary metabolites in Bacopa monnieri (L.) Pennell
Creators: name: Rupali Gupta
name: Akanksha Singh
name: P. V. Ajayakumar
name: Pandey, Rakesh
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Meloidogyne incognita (Kofoid and White) Chitwood a calamitous plant pathogen affects almost all the commercial crops, especially medicinal plants viz. Bacopa monnieri L. In this study, the efficacy of indigenous chitinolytic microbes against M. incognita in B. monnieri was evaluated under sterilised and natural soil conditions. The plant growth was observed for various parameters viz. nutrient uptake, phytochemical activities and secondary metabolites (bacoside). In the natural soil under green house conditions, the isolates significantly (P ≤ 0.05) reduced M. incognita infestation (1.38–2.78-folds) with significant increase in secondary metabolites (1.28–1.88-fold) over the untreated control. The potential strains were identified through 16S-rRNA as Streptomyces sp., Microbacterium arabinogalactanolyticum, Cellulosimicrobium cellulans, Actinomycetales bacterium, Chitiniphilus sp. and Flavobacterium johnsoniae. These findings thus highlight the potential of indigenous chitinolytic microbes that can be utilised for overall fitness of the plant along with the reduced root-knot nematode infestation in B. monnieri.
Additional file 1: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models
Creators: name: Sekiya, Michiko
name: Wang, Minghui
name: Fujisaki, Naoki
name: Sakakibara, Yasufumi
name: Quan, Xiuming
name: Ehrlich, Michelle
name: De Jager, Philip
name: Bennett, David
name: Schadt, Eric
name: Gandy, Sam
name: Ando, Kanae
name: Zhang, Bin
name: Iijima, Koichi
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Figure S1. No significant alteration in either the gross morphology of brain structures or the number of neuronal and glial cells was observed in TREM2/TYROBP flies. Figure S2. Molecular pathways affected by neuronal expression of Aβ42 and glial expression of TREM2/TYROBP. Figure S3. Molecular pathways affected by tau do not overlap with those affected by glial TREM2/TYROBP. Figure S4. Gene expression signatures in tau/TREM2/TYROBP flies. Figure S5. Heatmap showing the topological overlapping matrix (TOM) from weighted gene co-expression network analysis. Table S11. Primer sequences for RT-PCR and qRT-PCR. (PDF 4937 kb)
Towards Understanding Large-Scale Discourse Structures in Pre-Trained and Fine-Tuned Language Models
Creators: name: Huber, Patrick
name: Carenini, Giuseppe
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: With a growing number of BERTology work analyzing different components of pre-trained language models, we extend this line of research through an in-depth analysis of discourse information in pre-trained and fine-tuned language models. We move beyond prior work along three dimensions: First, we describe a novel approach to infer discourse structures from arbitrarily long documents. Second, we propose a new type of analysis to explore where and how accurately intrinsic discourse is captured in the BERT and BART models. Finally, we assess how similar the generated structures are to a variety of baselines as well as their distribution within and between models.
description: 9 pages
Investigation of the luminescence properties and thermal stability of dysprosium, terbium, and europium ions singly- and co-doped strontium yttrium borate phosphors
Creators: name: Xingya Wu
name: Yujun Liang
name: Shiqi Liu
name: Yingli Zhu
name: Xu, Rui
name: Miaohui Tong
name: Li, Kai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Plant Biology

description: A series of trivalent rare-earth element ions (europium, terbium, dysprosium) singly- and co-doped strontium yttrium borate phosphors was synthesized via the sol–gel method. The phase formation, luminescence properties, decay times, and energy transfer behaviors from terbium ions to europium ions, the thermal stability, and the Commission Internationale de L’Eclairage coordinates were investigated. Under the excitation of ultraviolet light, the singly doped phosphors exhibited green emission of terbium ions, white emission of dysprosium ions, and red emission of europium ions, respectively. For the terbium and europium ions co-doped strontium yttrium borate samples, a white emission can be realized by blending the doping concentration of terbium and europium ions. The critical distance between terbium and europium ions has been calculated to be about 14.52 Å and the energy transfer from terbium to europium occurred through the dipole–quadrupole interaction. At 150°C, the emission intensity of terbium and europium in the 12 mol% terbium and 14 mol% europium co-doped strontium yttrium borate sample was maintained at about 74% and 87% of their corresponding initial values, respectively, and the dysprosium ions singly doped strontium yttrium borate sample showed about 70% of its initial emission intensity at room temperature. The above results suggested that europium, terbium, dysprosium ions singly- and co-doped strontium yttrium borate phosphors have potential applications as ultraviolet-convertible phosphors.
Impact of COVID-19 policy changes on tropospheric NO₂ in the Yangtze River Basin: insights from GF-5 02 EMI-II observations
Creators: name: Huang, Yihui
name: Chen, Jian
name: Zhu, Keke
name: Cheng, Hua
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: This study evaluates the performance of the EMI-II (Environmental trace gases Monitoring Instrument-II) sensor in retrieving tropospheric NO₂ vertical column densities (VCDs) and investigates NO₂ concentration trends in the Yangtze River Basin following significant COVID-19 policy adjustments. Using comparative analyses with TROPOMI (TROPospheric Ozone Monitoring Instrument) and GEMS (Geostationary Environment Monitoring Spectrometer) products, EMI-II demonstrated robust capabilities in capturing NO₂ spatial distributions over key regions such as the Yangtze River Delta (YRD), North China Plain, and Sichuan-Chongqing urban clusters, with spatial correlation coefficients (r) reaching 0.94 and root mean square error (RMSE) as low as 1.98×10¹⁵ molecules/cm² in monthly comparisons, indicating strong agreement with established datasets. Following COVID-19 restrictions’ relaxation in December 2022 and the Spring Festival in January 2023, NO₂ levels in the Yangtze River Basin decreased by 26.94%, with specific declines of 41.90% in the YRD, 28.44% in central urban clusters, and 21.16% in the Sichuan–Chongqing region. These changes were driven by reduced vehicular emissions, industrial activity, and population mobility during the holiday period. The results underscore the interplay between anthropogenic activity, policy measures, and regional air quality, affirming EMI-II’s potential as a reliable tool for monitoring atmospheric pollutants and analyzing environmental responses to societal changes.
MMTAfrica: Multilingual Machine Translation for African Languages
Creators: name: Emezue, Chris C.
name: Dossou, Bonaventure F. P.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: In this paper, we focus on the task of multilingual machine translation for African languages and describe our contribution in the 2021 WMT Shared Task: Large-Scale Multilingual Machine Translation. We introduce MMTAfrica, the first many-to-many multilingual translation system for six African languages: Fon (fon), Igbo (ibo), Kinyarwanda (kin), Swahili/Kiswahili (swa), Xhosa (xho), and Yoruba (yor) and two non-African languages: English (eng) and French (fra). For multilingual translation concerning African languages, we introduce a novel backtranslation and reconstruction objective, BT\&REC, inspired by the random online back translation and T5 modeling framework respectively, to effectively leverage monolingual data. Additionally, we report improvements from MMTAfrica over the FLORES 101 benchmarks (spBLEU gains ranging from $+0.58$ in Swahili to French to $+19.46$ in French to Xhosa). We release our dataset and code source at https://github.com/edaiofficial/mmtafrica.
description: WMT Shared Task, EMNLP 2021 (version 2)
Sonar image denoising based on Noise2Void self-supervised learning
Creators: name: Ji, Yongqiang
name: Xie, Lan
name: Xu, Gaozheng
name: Zhu, Zheng
name: Gu, Yu
name: Fei, Jie
name: Li, Yuwei
name: Chen, Yao
name: Cai, Kuijie
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Sonar imaging plays a key role in underwater detection, and sonar denoising is essential for obtaining high-resolution images. Additive Gaussian noise and multiplicative speckle noise are two main sources which are widely distributed in sonar images and significantly degrading their quality. Due to the high exploration cost and complexity of the exploration environment of sonar images, traditional deep learning methods cannot be well applied to sonar images. In this study, we applied the Noise2Void method to train a U-Net for sonar image denoising. This method uses a self-supervised training method, which is well suited for sonar image denoising. It has two main advantages: Firstly, the method can suppress both the additive Gaussian noise and the multiplicative speckle noise, while most of the methods developed are effective for one type of noise; Secondly, the method can be trained with a single noisy image, while most of the supervised deep-learning methods are unsuitable for sonar-image denoising owing to limitations such as the acquisition cost of sonar images and lack of clean labelled data. We tested the proposed method on the SeabedObjects-KLGS dataset. Noise2Void demonstrates comparable or even superior performance to conventional methods in denoising, regardless of whether the noise is speckle or Gaussian in nature.
Antialgal activity of poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes against the marine alga Ulva
Creators: name: Wetra Yandi
name: Mieszkin, Sophie
name: Callow, Maureen E.
name: Callow, James A.
name: Finlay, John A.
name: Liedberg, Bo
name: Ederth, Thomas
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Plant Biology

description: Marine biofouling has detrimental effects on the environment and economy, and current antifouling coatings research is aimed at environmentally benign, non-toxic materials. The possibility of using contact-active coatings is explored, by considering the antialgal activity of cationic poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes. The antialgal activity was investigated via zoospore settlement and sporeling growth assays of the marine algae Ulva linza and U. lactuca. The assay results for PDMAEMA brushes were compared to those for anionic and neutral surfaces. It was found that only PDMAEMA could disrupt zoospores that come into contact with it, and that it also inhibits the subsequent growth of normally settled spores. Based on the spore membrane properties, and characterization of the PDMAEMA brushes over a wide pH range, it is hypothesized that the algicidal mechanisms are similar to the bactericidal mechanisms of cationic polymers, and that further development could lead to successful contact-active antialgal coatings.
The History of the Grid
Creators: name: Foster, Ian
name: Kesselman, Carl
Publisher: name: arXiv
Year: 2022
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: With the widespread availability of high-speed networks, it becomes feasible to outsource computing to remote providers and to federate resources from many locations. Such observations motivated the development, from the mid-1990s onwards, of a range of innovative Grid technologies, applications, and infrastructures. We review the history, current status, and future prospects for Grid computing.
Investigation of luminescence properties and thermal stability of dysprosium, terbium and europium ions singly- and co-doped strontium yttrium borate phosphors
Creators: name: Xingya Wu
name: Yujun Liang
name: Shiqi Liu
name: Yingli Zhu
name: Xu, Rui
name: Miaohui Tong
name: Li, Kai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Plant Biology

description: A series of trivalent rare-earth element ions (europium, terbium, dysprosium) singly- and co-doped strontium yttrium borate phosphors were synthesized via the sol-gel method. The phase formation, luminescence properties, decay times, energy transfer behaviors from terbium ions to europium ions, the thermal stability and Commission Internationale de L’Eclairage coordinates were investigated. Under the excitation of ultraviolet light, the singly doped phosphors exhibited green emission of terbium ions, white emission of dysprosium ions and red emission of europium ions, respectively. For the terbium and europium ions co-doped strontium yttrium borate samples, a white emission can be realized by blending the doping concentration of terbium and europium ions. The critical distance between terbium and europium ions has been calculated to be about 14.52 Å and the energy transfer from terbium to europium occurred through the dipole-quadrupole interaction. At 150 °C, the emission intensity of terbium and europium in the 12 mol% terbium and 14 mol% europium co-doped strontium yttrium borate sample was maintained at about 74% and 87% of their corresponding initial values, respectively, and the dysprosium ions singly- doped strontium yttrium borate sample showed about 70% of its initial emission intensity at room temperature. The above results suggested that europium, terbium, dysprosium ions singly- and co-doped strontium yttrium borate phosphor have potential applications as ultraviolet-convertible phosphors.
Numerical Simulations of Nearly Incompressible Viscoelastic Membranes
Creators: name: Barra, Valeria
name: Chester, Shawn A.
name: Afkhami, Shahriar
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: This work presents a novel numerical investigation of the dynamics of free-boundary flows of viscoelastic liquid membranes. The governing equation describes the balance of linear momentum, in which the stresses include the viscoelastic response to deformations of Maxwell type. A penalty method is utilized to enforce near incompressibility of the viscoelastic media, in which the penalty constant is proportional to the viscosity of the fluid. A finite element method is used, in which the slender geometry representing the liquid membrane, is discretized by linear three-node triangular elements under plane stress conditions. Two applications of interest are considered for the numerical framework provided: shear flow, and extensional flow in drawing processes.
description: already published
Thin viscoelastic dewetting films of Jeffreys type subjected to gravity and substrate interactions
Creators: name: Barra, Valeria
name: Afkhami, Shahriar
name: Kondic, Lou
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: This work presents a study of the interfacial dynamics of thin viscoelastic films subjected to the gravitational force and substrate interactions induced by the disjoining pressure, in two spatial dimensions. The governing equation is derived as a long-wave approximation of the Navier-Stokes equations for incompressible viscoelastic liquids under the effect of gravity, with the Jeffreys model for viscoelastic stresses. For the particular cases of horizontal or inverted planes, the linear stability analysis is performed to investigate the influence of the physical parameters involved on the growth rate and length scales of instabilities. Numerical simulations of the nonlinear regime of the dewetting process are presented for the particular case of an inverted plane. Both gravity and the disjoining pressure are found to affect not only the length scale of instabilities, but also the final configuration of dewetting, by favoring the formation of satellite droplets, that are suppressed by the slippage with the solid substrate.
description: already published
El dolor pélvico crónico en mujeres atletas: un estudio observacional
Creators: name: Vico-Moreno, Elena
name: Fernández-Domínguez, Juan Carlos
name: Bosch-Donate, Elisa
name: Oliva-Pascual-Vaca, Ángel
name: Sastre-Munar, Andreu
name: Romero-Franco, Natalia
Publisher: name: Psicosomàtica y Psiquiatría
Year: 2024

description: Psicosomàtica y Psiquiatría, Núm. 28 (2024): enero-febrero-marzo
FAIR data for the Life Sciences: we can and must do better!
Creators: name: Masuzzo, Paola
Publisher: name: Zenodo
Year: 2020
Subjects: fair data
open data
open science

description: I prepared this contribution for the Open Data Sicilia Raduno 2020.
 I talk about open research data, and what I have learned in my personal experience with implementing the FAIR principles. I make the case that we need to work on building communities of best practices and support these communities with the right tools and resources to make OPEN and FAIR become a reality.
Phenotypes, Origins and Functions of Regulatory B Cells in Autoimmune and Inflammatory Diseases
Creators: name: Molnarfi, Nicolas
Publisher: name: Université de Genève
Year: 2018
Subjects: info:eu-repo/classification/ddc/616.07
Regulatory B cells
Bregs
Autoimmunity
Autoimmune diseases
Inflammation

description: The ability of B cells to stimulate T cell–mediated immune responses through antigen presentation, co–stimulation and cytokine production has attracted great attention due to its significance for therapeutic intervention in inflammatory and autoimmune disorders. Nowadays, observations from a number of experimental approaches as well as in patients with inflammatory and autoimmune diseases have equally emphasized a significant function for B cells in maintaining immune homeostasis through maintenance of tolerance and prevention of unrestrained inflammation. Whereas studies by many investigators have started to identify the key mechanisms and molecules that support these processes, further effort is necessary to comprehend the diversity of regulatory B cell subsets and the cues that prompt their fate as regulatory versus proinflammatory. In this review I summarize the latest knowledge on the phenotypic and functional characteristics of different regulatory B cell populations, the cues that orchestrate their induction, and their potential therapeutic relevance.
When life is measured in drops: the intimate relation between urinary incontinence and mortality
Creators: name: John, Gregor Raphaël
Publisher: name: Université de Genève
Year: 2018
Subjects: info:eu-repo/classification/ddc/618.97
Incontinence urinaire
Mortalité
Facteurs de risque cardiovasculaire

description: Urinary incontinence (UI) is a frequent condition estimated to affect 423 billions individuals worldwide, and it adds an important burden to sufferers. Recently, UI has been associated with higher mortality in two meta-analyses. The association could results from an effect of confusion: many risk factors to develop UI are also risk factors for cardiovascular or pulmonary diseases (obesity, tobacco, high blood pressure). Interventional studies have demonstrated that loosing weight or increasing physical activity can prevent the development of UI in continent individuals, and favour resolution of leakage episodes in incontinent patients. Besides, these interventions are the mainstay behavioural modification to prevent cardiovascular premature death. Fall, infection, and depression are consequences of UI. Those three medical events are associated with morbidity and mortality. Finally, the physiopathology of UI still holds mysteries. The link between UI and death could hide in the disease mechanism: a genetic susceptibility, a perturbation in the microbiota, or an immune process. The present thesis composed of a personal publication series, explores the above mentioned hypotheses in the introduction section. Research perspectives are given along with the conclusions.
Fuzzy temporal convolutional neural networks in P300-based Brain-computer interface for smart home interaction
Creators: name: Vega, Christian Flores
name: Quevedo, Jonathan
name: Escandón, Elmer
name: Kiani, Mehrin
name: Ding, Weiping
name: Andreu-Perez, Javier
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Neural and Evolutionary Computing (cs.NE)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: The processing and classification of electroencephalographic signals (EEG) are increasingly performed using deep learning frameworks, such as convolutional neural networks (CNNs), to generate abstract features from brain data, automatically paving the way for remarkable classification prowess. However, EEG patterns exhibit high variability across time and uncertainty due to noise. It is a significant problem to be addressed in P300-based Brain Computer Interface (BCI) for smart home interaction. It operates in a non-optimal natural environment where added noise is often present. In this work, we propose a sequential unification of temporal convolutional networks (TCNs) modified to EEG signals, LSTM cells, with a fuzzy neural block (FNB), which we called EEG-TCFNet. Fuzzy components may enable a higher tolerance to noisy conditions. We applied three different architectures comparing the effect of using block FNB to classify a P300 wave to build a BCI for smart home interaction with healthy and post-stroke individuals. Our results reported a maximum classification accuracy of 98.6% and 74.3% using the proposed method of EEG-TCFNet in subject-dependent strategy and subject-independent strategy, respectively. Overall, FNB usage in all three CNN topologies outperformed those without FNB. In addition, we compared the addition of FNB to other state-of-the-art methods and obtained higher classification accuracies on account of the integration with FNB. The remarkable performance of the proposed model, EEG-TCFNet, and the general integration of fuzzy units to other classifiers would pave the way for enhanced P300-based BCIs for smart home interaction within natural settings.
GCSE Problem Solving scoring rubric
Creators: name: Jones, Ian
Publisher: name: Loughborough University
Year: 2017
Subjects: subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: This is an item produced for research purposes and is not a real GCSE exam rubric. The associated research item can be accessed at: https://doi.org/10.17028/rd.lboro.4609447
Incongruity between scientific knowledge and ordinary perceptions of nature: an ontological perspective for forest hydrology in Japan
Creators: name: Komatsu, Hikaru
name: Rappleye, Jeremy
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: There exists a significant incongruity between scientific knowledge and ordinary perceptions concerning the relation between forest and water (e.g. droughts and floods). Traditionally, forest hydrologists interpreted this incongruity using the deficit model, i.e. this incongruity is viewed as one that must be overcome through efforts to disseminate scientific knowledge more widely across society. However, one previous study suggested an alternative interpretation for the incongruity observed in Japan: the incongruity is induced by an enduring conflict between modern science and indigenous culture, one which purportedly promotes an “emotional” outlook to nature. This review attempts to clarify this alternative interpretation by utilizing a diverse range of disciplinary perspectives. We first clarify, using psychology and philosophy, that the “emotional” outlook of Japanese is rooted in a notion of self which is interdependent. Reviewing historical studies, we then find that the interdependent self was replaced by the notion of the independent self in the West in the Middle Ages. Since modern science was born out of this historical context in the seventeenth and eighteenth centuries, modern science assumes the same grammar of thought, i.e. begins with the notion of an independent self. We finally reveal that contemporary forest hydrology also has reproduced this grammar. We thus conclude that this difference in ontological grammar between contemporary forest hydrology and that of the ordinary public in Japan is a major cause for the incongruity between scientific knowledge and ordinary perceptions there. From this novel ontological perspective, we envision an alternative future of forest hydrology in Japan.
A Little Too Personal: Effects of Standardization versus Personalization on Job Acquisition, Work Completion, and Revenue for Online Freelancers
Creators: name: Hsieh, Jane
name: Hong, Yili
name: Burtch, Gordon
name: Zhu, Haiyi
Publisher: name: arXiv
Year: 2022
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: As more individuals consider permanently working from home, the online labor market continues to grow as an alternative working environment. While the flexibility and autonomy of these online gigs attracts many workers, success depends critically upon self-management and workers' efficient allocation of scarce resources. To achieve this, freelancers may develop alternative work strategies, employing highly standardized schedules and communication patterns while taking on large work volumes, or engaging in smaller numbers of jobs whilst tailoring their activities to build relationships with individual employers. In this study, we consider this contrast in relation to worker communication patterns. We demonstrate the heterogeneous effects of standardization versus personalization across different stages of a project and examine the relative impact on job acquisition, project completion, and earnings. Our findings can inform the design of platforms and various worker support tools for the gig economy.
description: CHI'22, April 29-May 5, 2022, New Orleans, LA, USA
Supplementary Material for: Make Precision Medicine Work for Chronic Kidney Disease
Creators: name: Sun, L.
name: Zou, L.-X.
name: Chen, M.-J.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Precision medicine is based on accurate diagnosis and tailored intervention through the use of omics and clinical data together with epidemiology and environmental exposures. Precision medicine should be achieved with minimum adverse events and maximum efficacy in patients with chronic kidney disease (CKD). In this review, the breakthroughs of omics in CKD and the application of systems biology are reviewed. The potential role of transforming growth factor-β1 in the targeted intervention of renal fibrosis is discussed as an example of how to make precision medicine work for CKD.
Information Sources and Search Strategy
Creators: name: Newman, Peter A.
Publisher: name: OSF Registries
Year: 2022

description: We developed the following list of databases to search in consultation with a specialist research librarian: Medline, Embase, Cochrane CENTRAL, Cochrane Covid-19 Study Register, PsychINFO, Sociological Abstracts, and the International Bibliography of the Social Sciences (IBSS).

We used modified versions of search strings using keywords and synonyms pertaining to vaccine hesitancy and COVID-19. These were guided by a research library database of COVID-19 search terms and a pre-COVID-19 systematic review of VH. For example, search terms included “vaccine hesitancy”, “vaccine refusal”, “vaccine confidence”, and “vaccine distrust”. Terms for COVID-19 included, for example, “corona virus” or “coronavirus” or “COVID” or “nCoV” or “SARS-CoV-2” along with adjacent terms “19” or “2019. An example search string is presented in S1 Appendix. Based on consultation with a research librarian, we decided not to use keywords to identify articles that met criteria for marginalized populations given the many complexities involved. Rather, after identifying articles focused on COVID-19, and VH and related constructs, we will use the screening and review process to determine which sources meet criteria for marginalization based on our pre-determined definition and initial population list.
MOESM1 of Effect of cultivation mode on the production of docosahexaenoic acid by Tisochrysis lutea
Creators: name: Hu, Hao
name: Ma, Lin-Lin
name: Shen, Xiao-Fei
name: Li, Jia-Yun
name: Wang, Hou-Feng
name: Zeng, Raymond
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1: Fig. S1. The bioreactor for culture of T. lutea under autotrophic and mixotrophic condition. Fig. S2. Production and content of DHA and TFAs from T. lutea by different carbon substrates. Values shown are averages of averages of three samples Âą standard deviation. (a): DHA content, production and proportion; (b): TFAs content and production. Acetate group found little content of DHA or TFAs, so not presented in the figure. Fig. S3. Cell morphology under three culture modes by100 times objective of the lens at the end of 16-days cultivation.
A simple model system for identifying arbuscular mycorrhizal fungal taxa that actively colonize rice (Oryza sativa L.) roots grown in field soil
Creators: name: Kobae, Yoshihiro
name: Ohtomo, Ryo
name: Norikuni Oka
name: Morimoto, Sho
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Ecology
subject: Science Policy
subject: Plant Biology

description: Even a few centimeters of roots in field soils can be colonized by genetically diverse arbuscular mycorrhizal (AM) fungi. The DNA sequences of AM fungi in roots suggest the fungal identities; however, it is difficult to determine which AM fungal taxa are physiologically active. In this study, we took advantage of the characteristics of rice (Oryza sativa L.) mycorrhizal roots, in which active colonization in roots is easily detected via histochemical staining of fungal succinate dehydrogenase activity (vital staining) and individual active colonization regions (infection units) in roots rarely coalesce. Root segments (< 3 mm) containing an active infection unit were dissected and squashed, large subunit (LSU) ribosomal RNA genes (rDNAs) were amplified using fungal universal primers and the sequences were directly determined by Sanger sequencing. All obtained sequences of colonization regions were of glomeromycotan origin. Phylogenetic analysis revealed that the levels of LSU-rDNA heterogeneity within an active colonization site were different among different clades. The methodology presented in this study offers researchers a novel tool for investigating the DNA information of physiologically active AM fungi in roots, whereas the factors that affect genetic diversity among active colonization remain to be clarified.
Pediatric Pathology: At the crossroads between development & tumorigenesis
Creators: name: Rougemont-Pidoux, Anne-Laure
Publisher: name: Université de Genève
Year: 2018
Subjects: info:eu-repo/classification/ddc/616.07
Pediatric pathology
Blastemal tumors
Developmental anomalies
Alagille syndrome

description: Tumors and developmental anomalies arising in the pediatric population are rare, or even considered as orphan diseases, and childhood solid tumors may rarely be encountered in the adult population. Increasing evidence essentially based on adult-type tumors occurring in children, or in adolescents and young adults, however points towards differences in terms of biological behavior, prognosis, and response to treatment according to the age groups, thereby suggesting the existence of distinct age-related categories of diseases. Therefore, not only better characterization, but also comparison between different age groups will allow better understanding of these tumors, and of their similarities or differences. A unique feature of pediatric embryonal or blastemal tumors is their striking resemblance to developing tissue or organs, albeit at various embryonal or fetal stages. Blastemal tumors may show heterologous differentiation, in accordance with an early pluripotent phenotype: for instance osteoid/bone formation may be seen in hepatoblastoma. Developmental pathways as well as developmental anomalies therefore provide insights into pediatric tumorigenesis. Conversely, the genetic landscapes of pediatric tumors may help delineate the various contributions of deviation from normal development pathways, or lineage specification. Molecular characterization of these rare pediatric tumors is underway. Despite similar morphological findings, pediatric tumors may show divergent biological behavior according to their molecular signature and to the patient age group. Therefore, molecular analyses should be strictly correlated to morphology, and to the multiple lines of differentiation displayed. Our group is involved in the study of both developmental anomalies and tumorigenesis, with a special focus on liver pathology. In particular, we studied the anomalies of the biliary tree development in the setting of Alagille syndrome, the generation of hepatocyte-like cells to replenish the liver in inborn errors of metabolism, and hepatoblastoma, a rare embryonal primary liver tumor. By the study of the molecular mechanisms and pathways underlying normal and abnormal development and further comparison with their counterparts in tumor development, we provided insights into developmental pathways, and opened perspectives into personalized patient treatment.
" ADN MITOCONDRIAL ASOCIADO A LA INFERTILIDAD POR VARICOCELE "-INVESTIGACIÓN DE TESIS DOCTORAL.
Creators: name: MARTI-BRENES, Prof.MARTÍ
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Education
subject: Análisis de la fragmentación del ADN asociado a la infertilidad por varicocele.

description: Diagnóstico y tratamiento del varicocele El varicocele se diagnosticó mediante la palpación del cordón espermático con el paciente de pie, tumbado y durante la maniobra de Valsalva. El reflujo de sangre venosa se confirmó mediante una ecografía Doppler dúplex (Toshyba Nemio SSA-550A Diagnostic Ultrasound System). Los sujetos fueron incluidos para la realización de una varicocelectomía mediante la técnica subinguinal microquirúrgica, ligando todas las venas dilatadas, conservando las arterias y glándulas linfáticas. Simultáneamente, se hizo una biopsia testicular (TESE) homolateral para la obtención de una muestra para anatomía patológica y el análisis de FADN en espermatozoides intratesticulares. Análisis de la fragmentación del ADN La FAD se realizó en muestras frescas de semen previo a la cirugía y testiculares obtenidas por extracción de espermatozoides del testículo, mediante el test de dispersión de la cromatina descrito por Fernández et al en 200314. Se trata de un método de desnaturalización y lisis de las proteínas nucleares, basado en el principio de que los espermatozoides cuyo ADN está intacto producirán un halo de dispersión que corresponde a la cromatina liberada de proteínas, pudiendo ser fácilmente analizado por microscopía óptica de fluorescencia (fig. 1). Para ello, utilizamos el kit comercial Halosperm® de Halotech Dna15. Valores de hasta el 27 ± 11% en el índice FADN se suelen considerar dentro de la normalidad en varones fértiles y normozoospérmicos. La muestra de semen se recolectó por masturbación tras 2-3 días de abstinencia. Las muestras frescas se procesaron siguiendo el protocolo que se describe en el kit Halosperm®. En testículo, extrajimos los espermatozoides de pequeñas cantidades del tejido biopsiado. Para ello, presionamos varias veces sobre la muestra utilizando unas pinzas, y resuspendimos con una pipeta de 1 ml. Retiramos el tejido y centrifugamos a 600 g durante 5 minutos. Desechamos el sobrenadante y resuspendimos en 50 μl debuffer fosfato salino estéril. Tomamos 10 μl y observamos la presencia de espermatozoides al microscopio. A partir de este punto, seguimos el protocolo descrito por el kit comercial. Accredited Doctor of Medical Sciences for the presentation of the Thesis.(2005)
Beyond 3DMM: Learning to Capture High-fidelity 3D Face Shape
Creators: name: Zhu, Xiangyu
name: Yu, Chang
name: Huang, Di
name: Lei, Zhen
name: Wang, Hao
name: Li, Stan Z.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: 3D Morphable Model (3DMM) fitting has widely benefited face analysis due to its strong 3D priori. However, previous reconstructed 3D faces suffer from degraded visual verisimilitude due to the loss of fine-grained geometry, which is attributed to insufficient ground-truth 3D shapes, unreliable training strategies and limited representation power of 3DMM. To alleviate this issue, this paper proposes a complete solution to capture the personalized shape so that the reconstructed shape looks identical to the corresponding person. Specifically, given a 2D image as the input, we virtually render the image in several calibrated views to normalize pose variations while preserving the original image geometry. A many-to-one hourglass network serves as the encode-decoder to fuse multiview features and generate vertex displacements as the fine-grained geometry. Besides, the neural network is trained by directly optimizing the visual effect, where two 3D shapes are compared by measuring the similarity between the multiview images rendered from the shapes. Finally, we propose to generate the ground-truth 3D shapes by registering RGB-D images followed by pose and shape augmentation, providing sufficient data for network training. Experiments on several challenging protocols demonstrate the superior reconstruction accuracy of our proposal on the face shape.
description: Accepted by T-PAMI 2022. see IEEE page http://ieeexplore.ieee.org/document/9748011
Supplementary Material for: Alexithymia and Plaque Psoriasis: Preliminary Investigation in a Clinical Sample of 250 Patients
Creators: name: Talamonti, M.
name: Galluzzo, M.
name: Servoli, S.
name: D'Adamio, S.
name: Bianchi, L.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background/Aims: Psoriasis as a dermatological disorder has complex effects on mental health and the psychological status of the patient. Many authors proposed that assessing how psoriasis affects a patient's life is better than a body surface area measurement for delineating psoriasis severity. Alexithymia is a personality dimension characterized by difficulty identifying feelings, difficulty describing feelings, and externally oriented thinking observed in many clinical conditions, especially in psychosomatic disorders. This study aimed to determine the prevalence of alexithymia in patients with plaque psoriasis compared with healthy participants, while taking into consideration demographic and clinical variables. Methods: We enrolled 250 patients with chronic plaque psoriasis, naïve to any systemic treatment, and 215 healthy individuals. The 20-item Toronto Alexithymia Scale (TAS-20) was used to assess alexithymia. Data analysis was done. Results: The mean TAS score was 53.5 (±15.3) for the patient group and 45.1 (±10.8) for controls (p < 0.0001). Compared to controls, the psoriasis group showed significant alexithymic features (32.4 vs. 9.3%), and no significant differences of alexithymia between patients with severe and mild psoriasis were observed. A significant relationship was determined between alexithymia and female gender and sensitive area involvement, such as the face, hands, and genital area. Conclusion: This study suggests that the assessment of alexithymia should be a part of the comprehensive care of patients with moderate to severe psoriasis. For this purpose, the TAS-20 is a useful and simple tool to be used in daily clinical practice.
Investigation of PDE5/PDE6 and PDE5/PDE11 selective potent tadalafil-like PDE5 inhibitors using combination of molecular modeling approaches, molecular fingerprint-based virtual screening protocols and structure-based pharmacophore development
Creators: name: Gülru Kayık
name: Tüzün, Nurcan Ş.
name: Durdagi, Serdar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The essential biological function of phosphodiesterase (PDE) type enzymes is to regulate the cytoplasmic levels of intracellular second messengers, 3′,5′-cyclic guanosine monophosphate (cGMP) and/or 3′,5′-cyclic adenosine monophosphate (cAMP). PDE targets have 11 isoenzymes. Of these enzymes, PDE5 has attracted a special attention over the years after its recognition as being the target enzyme in treating erectile dysfunction. Due to the amino acid sequence and the secondary structural similarity of PDE6 and PDE11 with the catalytic domain of PDE5, first-generation PDE5 inhibitors (i.e. sildenafil and vardenafil) are also competitive inhibitors of PDE6 and PDE11. Since the major challenge of designing novel PDE5 inhibitors is to decrease their cross-reactivity with PDE6 and PDE11, in this study, we attempt to identify potent tadalafil-like PDE5 inhibitors that have PDE5/PDE6 and PDE5/PDE11 selectivity. For this aim, the similarity-based virtual screening protocol is applied for the “clean drug-like subset of ZINC database” that contains more than 20 million small compounds. Moreover, molecular dynamics (MD) simulations of selected hits complexed with PDE5 and off-targets were performed in order to get insights for structural and dynamical behaviors of the selected molecules as selective PDE5 inhibitors. Since tadalafil blocks hERG1 K channels in concentration dependent manner, the cardiotoxicity prediction of the hit molecules was also tested. Results of this study can be useful for designing of novel, safe and selective PDE5 inhibitors.
MOESM2 of Cardiomyocyte-targeted and 17Î˛-estradiol-loaded acoustic nanoprobes as a theranostic platform for cardiac hypertrophy
Creators: name: Zhao, Xueli
name: Luo, Wen
name: Hu, Jing
name: Zuo, Lei
name: Wang, Jing
name: Hu, Rui
name: Wang, Bo
name: Xu, Lei
name: Li, Jing
name: Wu, Meng
name: Li, Pan
name: Liu, Liwen
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Additional file 2. Additional tables.
MOESM2 of Infectious bursal disease virus inoculation infection modifies Campylobacter jejuni–host interaction in broilers
Creators: name: Li, Li
name: Pielsticker, Colin
name: Han, Zifeng
name: Kubasová, Tereza
name: Rychlik, Ivan
name: Kaspers, Bernd
name: Rautenschlein, Silke
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2: Table S1. Histological bursal lesion of chickens at different time points after vvIBDV and C. jejuni-inoculation. ND = not done; SD = standard deviation; Exp. = experiment; BF = bursa of Fabricius; pbi = post bacterial (C. jejuni) inoculation. Different superscript letters indicate significant differences between groups (P < 0.05).
Relación entre fracaso escolar y los trastornos psicológicos en la infancia y la adolescencia. Psicopatología en la escuela postpandemia
Creators: name: Aguado Romo, Roberto
name: Anasagasti Undabarrena, Aritz
name: Martínez-Lorca, Manuela
name: Martínez-Lorca, Alberto
Publisher: name: Psicosomàtica y Psiquiatría
Year: 2024

description: Psicosomàtica y Psiquiatría, Núm. 28 (2024): enero-febrero-marzo