cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Unique islets in SE Asia: How Holocene climate and sea-level controlled growth of a coral reef island
Creators: name: Kappelmann, Yannis
name: Westphal, Hildegard
name: Wizemann, André
name: Mann, Thomas
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Coral reef islands are unconsolidated landforms, composed of skeletal carbonate from surrounding reefs and related ecosystems. Facing the predicted rise of sea-level and a changing environment in the next decades, response of low-lying coral reef islands is of great scientific and public interest. To better estimate future behavior, it is necessary to know and classify the effects of past environmental changes on the sedimentary system. In SE Asia, sedimentological understanding of the development of these landforms is still in infancy state, despite regional dependency on coral reef islands as habitable space. Here we provide a first comprehensive sedimentological study from the Spermonde Archipelago, Sulawesi, and simultaneously a unique data set in global coral reef island research. By analyzing sediment cores down to 10 m below island surface, we can reconstruct the sedimentary processes that ultimately formed the foundation of the recent landform. The main components of the sediment are coral fragments, constituting around 60% of the spectra, which underlines their importance for carbonate budgets. Gastropods also frequently contribute with about 20% to the sedimentary material, while foraminifera, bivalves and the green alga Halimeda are present only to a minor extent. Deposits from the early Holocene appear to be connected to hydrodynamic high-magnitude events. A significant depositional hiatus coincides with the onset of a mid-Holocene sea-level highstand in the study area. Rapid sedimentation occurs in late stages of subsequent sea-level fall, demonstrating how sensitive the dynamics of the sedimentary system are to changing environmental conditions. We can conclude that a small-scale sea-level fall of around 0.5 m enabled the formation of the coral reef island. Our final evolutionary model provides new and valuable insights for a better understanding of these landforms.
title: Wadi deposits of the Rotliegend revisited – key to unravel reservoir geometries in the Base Rotliegend of the Dutch-German border area
Creators: name: Felder, Marita
name: Burgess , Camille
name: Clever , Bert
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2020

description: An old play has recently been extended across the border from Germany into the Netherlands, an area previously thought to be barren of reservoir sandstones. The combination of core evaluation with observations from modern analogues help to refine the depositional geometries and architecture of the basal Upper Rotliegend play.
Translating the tech to expose the value: Disney does data
Creators: name: Hakins, Gemma
Publisher: name: Zenodo
Year: 2018
Subjects: Communications
Research Data
Disney
Simplexity
Engagement

description: Pixar Animations perfectly describe the strategic need to turn technically complex topics into concise and simple descriptions. "Simplexity: the balance between retaining the detail that supports the integrity of work, whilst enabling audiences to understand what you need them to".  Communicating the complexities around research data, their value and impact to non-technical audiences is vital when looking to demonstrate the wider benefits and secure funding. This Petcha Kutcha provides the foundations to develop strong communications across the data landscape and simplifies the process to create effective communications, whatever the topic or audience.
Thermoelectric Behavior Of Znte Materials And Its Characterization
Creators: name: M.Karunanithy
name: K. Mikila Vaahini
name: A. Hameedha Beevi
name: B.H. Ahmed Ibraheem
name: K. Kaviyarasu
name: A.Ayeshamariam
name: M.Jayachandran
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Maßnahmen zur Klimaanpassung über Wasserrückhalt und Kühlung durch Verdunstung für eine dürregefährdete Region in Ostdeutschland
Creators: name: Hildmann, Christian
name: Zimmermann, Beate
name: Schlepphorst, Rainer
name: Lukas, Stefan
name: Rösel, Lydia
name: Kleinschmidt, Friederike
name: Kruber, Sarah
Publisher: name: Zenodo
Year: 2022
Subjects: Klimawandel
Klimaanpassung
Wasserrückhalt
Evapotranspiration
Kühlung
Landwirtschaft
Forstwirtschaft
Naturschutz
Wasserwirtschaft
Siedlungsbereich

description: Die hier vorgestellte Auswahl von Maßnahmen ist im Projekt "Informationsgestützte antizipative wasserhaushaltsbasierte Anpassung an den Klimawandel" entstanden. Eine ausführlichere Beschreibung der Maßnahmen ist bereits veröffentlicht (siehe https://zenodo.org/record/6811079). Anpassung an den Klimawandel konfrontiert die Akteure im Landkreis Elbe-Elster, dem Projektgebiet, in erster Linie mit zunehmender Wasserknappheit. Durch die steigenden Temperaturen wird auch bei gleichbleibendem Niederschlag die klimatische Wasserbilanz immer negativer. Deshalb haben wir nach Maßnahmen gesucht, mit denen mehr Wasser in der Landschaft zurückgehalten werden kann. Das zurückgehaltene Wasser soll der Wasserversorgung der Vegetation dienen. So wirkt es sich positiv auf das Pflanzenwachstum aus, indem Dürrephasen gemildert werden und z.B. die Ertragssicherheit von Kulturen verbessert wird. Vor allem aber kommt es über den Verdunstungsprozess zur Kühlung der Landoberfläche. Die Kühlung der Landschaft über den Verdunstungsprozess trägt zur Dämpfung von Temperaturextremen bei. Klimaanpassung geht hier über die Bewältigung der Folgen des Klimawandels ein Stück weit hinaus, in dem das Kleinklima positiv beeinflusst wird. Damit Maßnahmen zur Klimaanpassung Wirkung zeigen können, müssen sie in der Fläche umgesetzt werden. Deshalb haben wir Maßnahmen aus allen relevanten Sektoren im Landkreis zusammengestellt: der Land- und Forstwirtschaft, dem Siedlungsbereich, dem Naturschutz und der Wasserwirtschaft.
Interpretation of compound words as lemmas (on the example of german-uzbek dictionaries)
Creators: name: Zayniddin Sanakulov
Publisher: name: figshare
Year: 2020
Subjects: subject: 200407 Lexicography
subject: FOS: Languages and literature

description: This article is devoted to lexicography, in which are described the principles of compound (words)-building units in dictionaries based on the scientific conclusions of mature lexicographers and analyzed their usage in existing German-Uzbek (translation) dictionaries.
Equations for calculating milligrams of morphine equivalents
Creators: name: Dasgupta, Nabarun
name: Kinlaw, Alan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020
Subjects: Drugs--Overdose
Pain--Treatment
Opioids

description: Equations describing 4 definitions for calculating milligrams of morphine equivalents (MME) per day for opioid analgesics.
The Aurora - Nature's Most Spectacular Light Show
Creators: name: Ledvina, Vincent
Publisher: name: Zenodo
Year: 2024

description: Auroras (e.g., Northern Lights) are moving curtains of color in the night sky. They are caused by charged particles from the sun channeled by Earth’s magnetism towards northern and southern polar areas. These particles cause the gasses in the air to glow. In recent weeks the sun’s activity has spiked creating auroras visible to many people even down to latitudes that rarely see them.

Our speaker is Vincent Ledvina, the “Aurora Guy”, a space physics Ph.D. student at the University of Alaska Fairbanks. He is also a “night sky photographer and aurora fanatic”. He will discuss the origins of auroras and share his adventures in chasing them and present many images he has amassed.

His website, http://theauroraguy.com, contains images, books, and merchandise to explore; a brief biography; and a short video about his work on auroras. He will bring these studies to life for us and answer questions you may have on aurora.
description: A recording of the presentation can be found here: https://youtu.be/M27IcvG4Fw0
D2.4 Cascading risks in the multimodal transportation platforms
Creators: name: Maliatsos, Kostas
name: Lyvas, Christos
name: Labrinoudakis, Costas
name: Menegatos, Andreas
name: Kalloniatis, Christos
name: Thrasyvoulos Giannakopoulos
Publisher: name: Zenodo
Year: 2022
Subjects: #CitySCAPE #H2020 #multimodaltransport #cybersecurity

description: This deliverable presents the results of the work carried out during Task 2.3 entitled “Mechanisms of cascading threats (across multimodal ecosystem)”. The main objective of the task is to develop a new methodology for analysis of interconnections and interdependencies between systems, assets and critical infrastructures, that will help model and accurately evaluate the infrastructure behaviour due to the propagation of cascading threats. In the initial project plan, this deliverable followed the completed risk and threat analysis conducted during Task 2.2. However, during the first stages of the analysis it was concluded that the methodology for analysis and modelling of cascading threats should be included in the final version of the risk analysis. Therefore, with the approval of the project coordinator and the project officer, it was decided that the results on cascading threat methodology should precede the final CitySCAPE risk and threat analysis results. Therefore, D2.4 “Cascading Risks in the Multimodal Transportation Platforms” can be considered as is Part 1 of the complete CitySCAPE Risk and threat analysis focusing on cascading threats for interdependent systems. In order to carry out the development of the new methodology, during this task: • the assets for the CPaaS system architectures were identified based on the use case definition from Task 2.1 of the CitySCAPE project, • the interfaces allowing access to the assets (entry points) and the possible interdependencies among them were extracted, • the composite system assets were further analysed in basic assets, based on the implementation information extracted by D2.1. As composite assets, we define high-level assets of the composite system, composed by various types of components and subsystems, that can be furtherly decomposed in more detailed basic generic assets • the cyber threats related to the basic assets and consequently the composite CPaaS assets were identified, • the analysis of the system allowed the investigation of interdependencies leading to a new methodology for cascading threat analysis, The results of D2.4 will be integrated into the complete risk and threat analysis methodology that is currently developed in Task 2.2 “Cross-domain threat analysis”. The developed methodology will be applied on the CitySCAPE CPaaS architectures and use cases.
Региональный центр мобилизации данных о биоразнообразии Севера Западной Сибири
Creators: name: Владимировна, Филиппова Нина
name: Бульонкова Татьяна Михайловна
name: Филиппов Илья Владимирович
name: Лапшина Елена Дмитриевна
Publisher: name: Zenodo
Year: 2020
Subjects: biodiversity, GBIF, biodiversity data mobilization, Specify

description: Открытые данные о биоразнообразии для устойчивого развития территории.
Supporting emergent bilinguals who use AAC (King et al., 2022)
Creators: name: King, Marika R.
name: Ward, Hannah
name: Soto, Gloria
name: Barrett, Tyson
Publisher: name: ASHA journals
Year: 2022
Subjects: Speech pathology
Communication technology and digital media studies
Multicultural, intercultural and cross-cultural studies

description: Purpose: The purpose of this project was to examine the effect of the COVID-19 pandemic on speech-language pathologist (SLP) service provision for emergent bilinguals who use augmentative and alternative communication (AAC). One prominent issue in AAC service delivery is the efficacy and feasibility of providing AAC services via telepractice. The COVID-19 pandemic intensified this issue as most providers, clients, and families adjusted to remote service delivery models. While emerging evidence supports telepractice in AAC, little is known about the potential benefits and challenges of telepractice for emergent bilinguals who use AAC and their families. Method: Data were collected via a nationwide survey. Licensed SLPs (N = 160) completed an online questionnaire with Likert-type, multiple-choice, and open-ended questions, analyzed using mixed methods. Results: Findings illustrated a shift in service delivery from in-person to telepractice and hybrid (both telepractice and in-person) models. Overall, child intervention outcomes declined for emergent bilinguals who used AAC during the COVID-19 pandemic, regardless of service delivery format. However, collaboration increased for many providers and families. Qualitative analyses highlighted barriers to AAC service provision for emergent bilinguals who use AAC that were exacerbated by the COVID-19 pandemic, as well as factors that facilitated collaboration and family engagement. Conclusion: These findings suggest that, despite challenges, telepractice or hybrid services may be a promising approach to provide more culturally responsive, family-centered care for emergent bilinguals who use AAC.
 Supplemental Material S1. Survey.
 Supplemental Material S2. Qualitative coding scheme.
 King, M., Ward, H., Soto, G., & Barrett, T. S. (2022). Supporting emergent bilinguals who use augmentative and alternative communication and their families: Lessons in telepractice from the COVID-19 pandemic. American Journal of Speech-Language Pathology. Advance online publication. https://doi.org/10.1044/2022_AJSLP-22-00003
Morphismes de Belyi simplement ramifiés - Application à la réduction des arbres en genre 0
Creators: name: Gabriel, Soranzo
Publisher: name: Zenodo
Year: 2022
Subjects: Children's drawing

description: We develop here all the material to study the reduction (modulo a prime number) of Children drawings and trees. We give then a criterion to get a good reduction of trees only with good reduction at one of the three critical points in case of wise ramification.
Faciliter la collaboration entre agriculteurs
Creators: name: Van Vooren, Laura
name: Jamart, An
Publisher: name: Zenodo
Year: 2022
Subjects: DiverIMPACTSPA
Acteurs
Bio
Obstacles et Catalyseurs
Apprentissage

description: Problème La coopération entre agriculteurs spécialisés peut améliorer la diversification des cultures et fermer les cycles locaux de nutriments. Cependant, les agriculteurs de différents secteurs n'entrent généralement pas en contact et l'expérience en matière de création et maintien de collaborations fait défaut. Solution La coopération a été stimulée par la mise en place de réunions régionales entre agriculteurs, l'organisation d'ateliers autour de thèmes communs et le soutien aux partenariats existants.
Multimodal Sleep Monitoring Across the 24-h Day for Dementia
Creators: name: Kalantari, Elaheh
name: Skeldon, Anne
name: Monica, Ciro Della
name: Revell, Victoria
name: Atzori, Giuseppe
name: Hilton, Adrian
name: Derk-Jan Dijk
name: Samaneh Kouchaki
Publisher: name: Zenodo
Year: 2022

description: Sleep disturbances have been reported as one of the most common symptoms among people living with dementia (PLWD). Few technologies to longitudinally monitor sleep across the 24-h day are available. Here, we develop machine learning models that use multimodal data to accurately monitor sleep across the day and night.
Access To Databases (Full Scale Pilot 7)
Creators: name: Lux, Zoltán
name: Mezei, József
name: Alföldi, István
name: Anderson, David
name: Anderson, Janet
Publisher: name: Zenodo
Year: 2018
Subjects: E-ARK
Pilot
Database Access

description: This report contains information gathered during the execution of E-ARK Pilot 7: SIP Access to Databases.
A Study on Diesel Engine Combustion
Creators: name: MD MOHAIMEEN UL ISLAM
Publisher: name: figshare
Year: 2020
Subjects: subject: 91101 Marine Engineering
subject: FOS: Environmental engineering
subject: Mechanical Engineering
subject: FOS: Mechanical engineering
subject: 90201 Automotive Combustion and Fuel Engineering (incl. Alternative/Renewable Fuels)
subject: 91305 Energy Generation, Conversion and Storage Engineering

description: The application of diesel engine has been rising dramatically since it’s invention and the usages have speared in the field of transportation, agriculture, constructions and what not. Due to its colossal power, this engine has become prominent whenever thinking about heavy duty performances. Diesel engine ignites fuel into combustion chamber, where air is pressurized by the upward stroke of the piston. As it is an internal combustion engine, the operation follows the order that can be obtained by two stroke or four stroke cycle. However, in both cycles the fuel energy converted into machinery energy to produce power. The present study indicates the factors which need to be prioritized for appropriate combustion and the fuel characteristics on which the engine’s efficiency depends. Moreover, in order to carry appropriate combusting and the safe operation of engine some effective measures are identified by scrutinizing the diesel engine used for heavy duty performance.
Business Archives (Pilot Definition: Pilot 4)
Creators: name: Ruusalepp, Raivo
name: Rand, Ats
name: Alföldi, István
name: Anderson, David
name: Anderson, Janet
Publisher: name: Zenodo
Year: 2018
Subjects: E-ARK
Pilot
Business Archives

description: This technical note sets out the definition of E-ARK Pilot 4: Business Archives
Πέτρου ελαχίστου Επισκόπου Αργείων. Επιτάφιος εις τον μακάριον Αθανάσιον Επίσκοπον Μεθώνης. Οι πλατωνικές αρετές ενός αγίου του Θ΄αιώνος.
Creators: name: Τσουρή, Αικατερίνη
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2022
Subjects: subject: Πέτρος -- Άγιος, Επίσκοπος Άργους, 9ος αι. -- Επιτάφιος εις τον μακάριον Αθανάσιον Επίσκοπον Μεθώνης
subject: Πέτρος -- Άγιος, Επίσκοπος Άργους, 9ος αι. -- Ερμηνεία και κριτική
subject: Αθανάσιος -- Άγιος, Επίσκοπος Μεθώνης
subject: Χριστιανοί άγιοι -- Ελλάδα -- Μεθώνη
subject: Πλάτων , 427-347 π.Χ. -- Επίδραση
subject: Μεθώνη
subject: Άγιος Αθανάσιος
subject: Πλατωνικές αρετές
subject: Επιτάφιος λόγος
subject: Methoni
subject: Saint Athanasios
subject: Platonic virtues
subject: Epitaph speech

description: Ο Άγιος Πέτρος Άργους αντλώντας στοιχεία από τον χαμένο στις μέρες μας Βίο του Αγίου Αθανασίου Μεθώνης συγγράφει και εκφωνεί τον Επιτάφιο Λόγο του, ένα εκκλησιαστικό εγκώμιο που αποτελεί επί της ουσίας βιογράφιση του Αγίου Αθανασίου Μεθώνης ακολουθώντας πιστά τους κανόνες της βυζαντινής ρητορικής τέχνης, με σκοπό να κατηχήσει τους συνελεγμένους γύρω από το τάφο του Αγίου χριστιανούς. Στο προοίμιο του ρητορικού του λόγου (κεφάλαια 1 και 2) εξηγεί τους λόγους που αναλαμβάνει το έργο αυτό και ποιές δυσκολίες αντιμετωπίζει. Στη συνέχεια, ξεκινά να εγκωμιάζει την επίγεια και ουράνια πατρίδα του Αγίου Αθανασίου καθώς και τους γονείς του (κεφάλαια 3 και 4) αναφέροντας καίρια χαρακτηριστικά της χριστιανικής φιλοσοφίας μέσω παραβολών σε συνδυασμό με πλατωνικά στοιχεία και ψυχικές αρετές (κεφάλαια 5, 6 και 7). Η κλιμάκωση έρχεται στη σύγκριση που κάνει με σπουδαίους νομοθέτες της αρχαίας Ελλάδας (κεφάλαιο 8), καθώς και με διάφορες μεγάλες προσωπικότητες της Βίβλου (κεφάλαια 9 και 10) για να καταλήξει στην περιγραφή του θανάτου του που λογίζεται ως θάνατος φιλοσόφου (κεφάλαια 11, 12 και 13) καταγράφοντας με πλατωνικές πινελιές τα τελευταία του λόγια, χωρίς καμία αναφορά σε θαύματα, εκτός από τη μοναδική στο μύρο που αναβλύζει από τον τάφο του Αγίου (κεφάλαιο 14). Αξίζει να τονιστεί ότι ο Άγιος Πέτρος Άργους ενδιαφέρεται να παρουσιάσει τον ήρωά του ως πρότυπο αγιότητας, στο πρόσωπο του οποίου συγκεντρώνονται οι τέσσερις γενικές αρετές, δηλαδή η σοφία, η ανδρεία, η δικαιοσύνη και η σωφροσύνη για τις οποίες κάνει λόγο ο Πλάτωνας στην Πολιτεία του, καθιστώντας τις έκδηλες σε όλο το κείμενό του.
Supplemental Web Files for "Genomic characterization of autozygosity and recent inbreeding trends in all major breeds of US dairy cattle"
Creators: name: Lozada-Soto, Emmanuel A.
name: Tiezzi, Francesco
name: Jiang, Jicai
name: Cole, John B
name: VanRaden, Paul M
name: Maltecca, Christian
Publisher: name: figshare
Year: 2022
Subjects: subject: 70201 Animal Breeding
subject: FOS: Animal and dairy science

description: Online repository for supplementary files for Journal of Dairy Science paper.
A PHENOMENOLOGICAL STUDY: HOW UNDOCUMENTED AND DACAMENTED STUDENTS FEEL ABOUT SUPPORT THEY RECEIVE AT TWO CALIFORNIA COMMUNITY COLLEGES WHEN STATE AND FEDERAL IMMIGRATION POLICIES DO NOT ALIGN
Creators: name: Maestas, Adriana
Publisher: name: Zenodo
Year: 2022
Subjects: undocumented students
California community colleges
levels of support
DREAMers
DACA

description: The purpose of this qualitative study was to explore the experiences of undocumented students and DACAmented students attending community college in the aftermath of the Trump administration, which had taken a hardline, anti-immigrant stance in contrast to the more welcoming environment toward immigrants that the state of California had adopted with its policies that impact immigrants. This study explored how students felt about the level of support that they received at their respective community colleges. Thirteen semistructured interviews were conducted with undocumented students. UndocuCrit (Aguilar, 2018) was used as a theoretical framework to provide a lens for analysis of the students’ stories. Overall, students felt supported in their studies at their respective institutions, and they felt the level of received support was adequate. Emerging themes provided a contrast of hardship and looking forward to the future with the following themes: struggle, denial/avoidance, fear, optimism, self-reliance/resourcefulness, and validation.
Endometriosis presenting as a rectal submucosal tumour
Creators: name: Fonseca, Diogo
Publisher: name: EURORAD
Year: 2018
Subjects: subject: Pelvis
subject: MR
subject: MR-Diffusion/Perfusion
subject: Ultrasound
subject: Diagnostic procedure
subject: Endoscopy
subject: Tissue characterisation

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: female, 52 years
description: Clinical History: 52-year-old asymptomatic woman with no significant past medical history presented for a routine colonoscopy screening. During the colonoscopy a submucosal lesion was detected on the anterior wall of the middle rectum. No biopsy was done at the time and an... Final Diagnosis: Endometriosis
Design, crystal structure determination, molecular dynamic simulation and MMGBSA calculations of novel p38-alpha MAPK inhibitors for combating Alzheimer’s disease
Creators: name: Iqbal, Saleem
name: Potharaju, Raju
name: Naveen, S.
name: Lokanath, N. K.
name: Mohanakrishnan, Arasambattu K.
name: Gunasekaran, Krishnasamy
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The hallmark of the Alzheimer’s disease (AD) is the accumulation of aggregated, misfolded proteins. The cause for this accumulation is increased production of misfolded proteins and impaired clearance of them. Amyloid aggregation and tau hyperphosphorylation are the two proteinopathies which accomplish deprivation of cell and tissue hemostasis during neuropathological process of the AD, as a result of which progressive neuronal degeneration and the loss of cognitive functions. p38 mitogen-activated protein kinase (p38 MAPK) has been implicated in both the events associated with AD: tau protein phosphorylation and inflammation. p38α MAPK pathway is activated by a dual phosphorylation at Thr180 and Tyr182 residues. Clinical and preclinical evidence implicates the stress related kinase p38α MAPK as a potential neurotherapeutic target. Drug design of p38α MAPK inhibitors is mainly focused on small molecules that compete for Adenosine triphosphate in the catalytic site. Here we have carried out the synthesis of phenyl sulfonamide derivatives Sulfo (I) and Sulfo (II). Crystal structures of Sulfo (I) and Sulfo (II) were solved by direct methods using SHELXS-97. Sulfo (I) and Sulfo (II) have Rint values of 0.0283 and 0.0660, respectively, indicating good quality of crystals and investigated their ability against p38α MAPK. Docking studies revealed that the Sulfo (I) had better binding affinity (−62.24 kcal/mol) as compared to Sulfo (II) and cocrystal having binding affinity of −54.61 kcal/mol and −59.84 kcal/mol, respectively. Molecular dynamics simulation studies of Sulfo (I) and cocrystal of p38α MAPK suggest that during the course of 30 ns simulation run, compound Sulfo (I) attained stability, substantiating the consistency of its binding to p38α MAPK compared to cocrystal. Binding free energy analysis suggests that the compound Sulfo (I) is better than the cocrystal. Thus, this study corroborates the therapeutic potential of synthesized Sulfo (I) in combatting AD. Communicated by Ramaswamy H. Sarma
Fe2O3 Thin Films On Deposited On Ito Substrate And Its Rbs Characterization
Creators: name: R. Abinaya
name: P.Ponsurya
name: B.H. Abbas Shahul Hameed
name: S. Kathoon Sanofer
name: S. Rajathi
name: R. Perumalsamy
name: A. Ayeshamariam
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Molecular dynamics of hERG channel: insights into understanding the binding of small molecules for detuning cardiotoxicity
Creators: name: Koulgi, Shruti
name: Jani, Vinod
name: Nair, Vinay
name: Saini, Jagmohan S.
name: Phukan, Samiron
name: Sonavane, Uddhavesh
name: Joshi, Rajendra
name: Kamboj, Raj
name: Palle, Venkata
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Evaluation of cardiotoxicity potential of new chemical entities (NCEs) has lately become one of the stringent filters in the drug discovery and development process. Cardiotoxicity is caused mainly by the inhibition of human ether-a-go-go related gene (hERG) channel protein. Inhibition of the hERG channel leads to a life-threatening condition known as cardiac arrhythmia. Knowledge of the structural behaviour of the hERG would aid greatly in the design of new drug molecules that do not interact with the protein and add to the safety index. In this study, a computational model for the active-state of hERG was developed. This model was equilibrated by performing the molecular dynamics simulations for 100 ns followed by clustering and selection of a representative structure based on the largest populated cluster. To study the changes in the protein structure on inhibition, three inhibitory ligands, namely, dofetilide, cisapride and terfenadine were docked, followed by molecular dynamics simulations of 200 ns for the apo and each ligand-bound structure. It was observed that docking and simulation studies of the hERG model exhibited noticeable conformational changes in the protein upon ligand-binding. A significant change in the kink of the S6-transmembrane helix was observed. Inter-chain distances between the crucial residues Y652 and F656 (present below the ion-selectivity filter), their side-chain orientation and hydrogen bonding indicated a probable collapse of the pore. These changes may infer the initiation in transition of hERG from an open to an inactive state. Hence, these findings would help in designing compounds devoid of hERG inhibition with reduced cardiotoxicity. Communicated by Ramaswamy H. Sarma
Supplementary document for Interferometric measurements of nonlinear refractive index in the infrared spectral range - 5943718.pdf
Creators: name: Jansonas, Gaudenis
name: Budriunas, Rimantas
name: Vengris, Mikas
name: Varanavicius, Arunas
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: subject: 20503 Nonlinear Optics and Spectroscopy
subject: FOS: Physical sciences

description: Supporting figures and tables.
Recent Development in Friction Stir Welding Process: A Review
Creators: name: Soori, Mohsen
name: Asmael, Mohammed
name: Davout Solyali
Publisher: name: figshare
Year: 2020
Subjects: subject: 91099 Manufacturing Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The Friction stir welding (FSW) is recently presented so to join different materials without the melting process as a solid-state joining technique. A widely application for the FSW process is recently developed in automotive industries. To create the welded components by using the FSW, the plunged probe and shoulder as welding tools are used. The Finite Element Method (FEM) can be used so to simulate and analyze material flow during the FSW process. As a result, thermal and mechanical stresses on the workpiece and welding tool can be analyzed and decreased. Effects of the welding process parameters such as tool rotational speed, welding speed, tool tilt angle, depth of the welding tool, and tool shoulder diameter can be analyzed and optimized so to increase the efficiency of the production process. Material characteristics of welded parts such as hardness or grain size can be analyzed so to increase the quality of part production. Residual stress, strain, deformation, and estimations of the temperatures in the welding area can be predicted using the simulation of FSW in the FEM software. Heat generation, thermal, and thermomechanical analyses can also be implemented on the welded parts to analyze the distribution of temperature and strain in the heat-affected zone (HAZ). Moreover, welding operations of dissimilar metals can be analyzed using numerical simulation to increase the capabilities of the welding methodology in different industrial applications. In this article, a review of the FSW process is presented. As a result, the research filed can be moved forward by reviewing and analyzing recent achievements in the published papers.
Memoria del Encuentro Regional: Innovación para el desarrollo:una visión para la sostenibilidad de la agricultura familiar
Creators: name: Platero, Gonzalo Galileo Rivas
name: Rodríguez, Esteban López
name: López, Karen Montiel
name: Solano, Andrea Méndez
Publisher: name: Zenodo
Year: 2014
Subjects: Innovación agropecuaria
PRESICA
Agricultura familiar
Investigación-extensión agropecuaria

description: Durante los días 26 y 27 de agosto del 2014 se llevó a cabo en la Sede Central del Instituto Interamericano de Cooperación para la Agricultura (IICA) el evento denominado “Encuentro Regional de Innovación para el desarrollo: una visión para la sostenibilidad de la agricultura familiar”, el cual se organizó en el marco de las actividades de cierre del proyecto regional: “Estrategia de Innovación Tecnológica para Mejorar la Productividad y Competitividad de Cadenas Producto en Centroamérica y República Dominicana” (PRESICA), iniciativa financiada por el Banco Interamericano de Desarrollo (BID), el Fondo Regional de Tecnología Agropecuaria (FONTAGRO) y fue ejecutado por el IICA junto a los Institutos Nacionales de Investigación Agrícola de la región. El encuentro de innovación consistió en tres actividades claves: un foro de innovación, un taller sobre experiencias y resultados del proyecto PRESICA y un taller sobre buenas prácticas de innovación para el desarrollo. El foro contó con distinguidos panelistas de diferentes organizaciones y con productores de la región centroamericana que expresaron diferentes planteamientos sobre la innovación en el ámbito agropecuario. En el taller sobre experiencias y resultados del PRESICA se analizaron las lecciones aprendidas y discutieron conclusiones y recomendaciones para impulsar proyectos con esta visión de innovación. En cuanto al taller sobre buenas prácticas de innovación para el desarrollo, se presentaron diferentes experiencias, ideas y metodologías que aportan al mejoramiento de propuestas para integrar o incluir la innovación en el ámbito de las políticas públicas. El foro y los talleres del Encuentro se llevaron a cabo mediante paneles, los cuales fueron diálogos dirigidos a través de preguntas orientadoras, donde cada panelista y la audiencia motivaron un proceso de discusión y análisis alrededor de la innovación, el desarrollo sostenible y los consorcios de innovación en el ámbito rural, como herramientas para instituir una verdadera cultura de innovación y fortalecer así los propios Sistemas de Innovación en los países. Adicionalmente, se discutió sobre la necesidad de que estas experiencias queden documentadas y que respalden los procesos de incidencia política.
Steps toward incentivizing data and software sharing
Creators: name: Erdmann, Christopher
Publisher: name: Zenodo
Year: 2022
Subjects: Data and Software Sharing

description: Invited talk on "Incentivising data and software sharing" at EarthCube Model Data RCN, July 25 - 27, 2022, University of North Dakota, Grand Forks EarthCube RCN, “What About Model Data?” Determining Best Practices for Preservation and Replicability | Project Information Website (modeldatarcn.github.io)
description: This work is supported by Accelerating Open and FAIR Data Practices Across the Earth, Space, and Environmental Sciences: A Pilot with the NSF to Support Public Access to Research Data project funded by the National Science Foundation, Grant 2025364.
NASA Transform to Open Science July 2022 Community Forum - Mentimeter Results
Creators: name: Hall, Cynthia
Publisher: name: Zenodo
Year: 2022

description: NASA’s Transform to Open Science (TOPS) mission is being designed to support the adoption of open science and broaden participation in science. During the 2023 Year of Open Science TOPS is planning a broad suite of resources, events, and activities. TOPS efforts are built on relationships with a variety of diverse communities. Critical to these relationships is open, candid, and complete two-way communication. In the spirit of openness and transparency, this community forum presentation focuses on the introductory suite of the TOPS open science curricula, OpenCore. During the presentation, we asked the community questions related to the modules as well as their perspectives on open science. These are the Mentimeter results.
Energy Policy for Uganda Using OSeMOSYS
Creators: name: Babukiika, Fiona
Publisher: name: Zenodo
Year: 2024
Subjects: Energy Evaluation, Energy Modelling, Energy Policy, Strategic Planning, Energy Sustainability, Future Visions, OSeMOSYS, Flex Tool

description: Energy system modelling can serve to evaluate two scenarios and aid in enhancing policymaking. However, a common obstacle to initiating energy system modelling in developing nations is the limited access to data, leading to delays. Consequently, this work offers a dataset that can facilitate the creation of a basic energy system model for Uganda, serving as an initial step for subsequent model refinement and scenario analysis. The dataset is sourced entirely from publicly available and accessible outlets such as international organizations' websites, databases, journal articles, and existing modelling studies. This ensures that the dataset can be easily updated with the latest information or more precise local data. These data were used to calibrate a straightforward energy system model using the Open Source Energy Modelling System (OSeMOSYS), incorporating two simplified scenarios (Business As Usual and the Renewable Energy by 2050) spanning from 2020 to 2030. The assumptions made and outcomes of these scenarios are outlined in the methodology, serving as an illustrative demonstration of the possibilities with this dataset. This basic model can be tailored and expanded upon by local analysts and academics, providing a foundation for future work.
In silico evaluation of lapachol derivatives binding to the Nsp9 of SARS-CoV-2
Creators: name: Nicolau, Nilson
name: Santos, Igor Andrade
name: Meireles, Bruno Amaral
name: Nicolau, Mariana Sant’Anna Pereira
name: Lapa, Igor Rodrigues
name: Aguiar, Renato Santana
name: Jardim, Ana Carolina Gomes
name: José, Diego Pandeló
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: SARS-CoV-2 is the etiological agent of COVID-19, which represents a global health emergency that was rapidly declared a pandemic by the World Health Organization. Currently, there is a dearth of effective targeted therapies against viruses. Natural products isolated from traditional herbal plants have had a huge impact on drug development aimed at various diseases. Lapachol is a 1,4- naphthoquinone compound that has been demonstrated to have therapeutic effects against several diseases. SARS-CoV-2 non-structural proteins (nsps) play an important role in the viral replication cycle. Nsp9 seems to play a key role in transcription of the RNA genome of SARS-CoV-2. Virtual screening by docking and molecular dynamics suggests that lapachol derivatives can interact with Nsp9 from SARS-CoV-2. Complexes of lapachol derivatives V, VI, VIII, IX, and XI with the Nsp9 RNA binding site were subjected to molecular dynamics assays, to assess the stability of the complexes via RMSD. All complexes were stable over the course of 100 ns dynamics assays. Analyses of the hydrogen bonds in the complexes showed that lapachol derivatives VI and IX demonstrated strongest binding, with a stable or increasing number of hydrogen bonds over time. Our results demonstrate that Nsp9 from SARS-CoV-2 could be an important target in prospecting for ligands with antiviral potential. In addition, we showed that lapachol derivatives are potential ligands for SARS-CoV-2 Nsp9. Communicated by Ramaswamy H. Sarma
β-Lactoglobulin-gold nanoparticles interface and its interaction with some anticancer drugs – an approach for targeted drug delivery
Creators: name: Waghmare, Manik N.
name: Qureshi, Tazeen S.
name: Krishna, C. Murali
name: Pansare, Kshama
name: Gadewal, Nikhil
name: Hole, Arti
name: Dongre, Prabhakar M.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: The protein-nanoparticle interface plays a crucial role in drug binding and stability, in turn enhancing efficacy in targeted drug delivery. In the present study, whey protein β-lactoglobulin (BLG) is conjugated with gold nanoparticles (AuNP) and its interaction with curcumin (CUR) and gemcitabine (GEM) has been explored. Further, AuNP-BLG conjugate interactions with anticancer drugs were characterized using dynamic light scattering (DLS), zeta potential, UV-visible, Raman spectroscopy, fluorescence, circular dichroism along with molecular dynamics simulation. The cytotoxicity studies were performed using breast cancer cell lines (MCF-7). ∼8 µM of BLG resides on AuNP (∼29 nm) surface revealed by DLS. Raman scattering of AuNP-BLG conjugate showed orientation of the central calyx of BLG towards solvent. BLG fluorescence confirmed the interaction between AuNP-BLG conjugate with drugs and indicated strong binding and affinity (for CUR KD = 3.71 x 108 M −1, n = 1.83, and for GEM KD = 3.78 x 103 M −1, n = 0.94), enhanced in the presence of AuNP. CD and Raman analysis exhibited selective hydrophilic and hydrophobic conformations induced by drug binding. Computational studies on BLG-drug complexes revealed that the residues Pro38, Leu39 and Met107 are largely associated with CUR binding, while GEM interaction is via hydrophilic contacts which significantly matches with spectroscopic investigation. IC50 values were calculated for all components of this loading system on MCF-7. The possible mechanisms of interaction between AuNP-BLG with anticancer drugs has been explored at the molecular level. We believe that these conjugates could be considered in the targeted drug delivery studies for cancer research. Communicated by Ramaswamy H. Sarma
title: Φωτοβολταϊκός μετατροπέας DC/AC για την παροχή επικουρικών υπηρεσιών σε ηλεκτρικά δίκτυα
title: Photovoltaic DC/AC power converter for the provision of ancillary services in electric grids
Creators: name: Στασινος Αποστολος
Publisher: name: Technical University of Crete
Year: 2020

description: Σε αυτή τη διπλωματική εργασία παρουσιάζεται η εφαρμογή μεθόδων για την παροχή επικουρικών υπηρεσιών στο ηλεκτρικό δίκτυο από μονοφασικό φωτοβολταϊκό αντιστροφέα DC-AC. Μέσω του φωτοβολταϊκού αντιστροφέα DC-AC, δίνεται η ικανότητα στο φωτοβολταϊκό σύστημα μιας οικίας να προσφέρει υπηρεσίες έγχυσης αέργου ισχύος και απόσβεσης αρμονικών συνιστωσών του ρεύματος στο ηλεκτρικό δίκτυο. Υλοποιήθηκε και προσομοιώθηκε το μοντέλο του φωτοβολταϊκού συστήματος στο λογισμικό Simulink του Matlab ώστε να μελετηθεί η ικανότητα του φωτοβολταϊκού αντιστροφέα DC-AC να παρέχει επικουρικές υπηρεσίες στο ηλεκτρικό δίκτυο. Στην υλοποίηση του φωτοβολταϊκού συστήματος χρησιμοποιήθηκαν δύο μέθοδοι για τη μέγιστη απόδοση ισχύος της φωτοβολταϊκής συστοιχίας: η μέθοδος P&O MPPT για την περίπτωση ομοιόμορφης προσπίπτουσας ηλιακής ακτινοβολίας και η μέθοδος PSO MPPT για την περίπτωση μερικής σκίασης. Επιπλέον για τον έλεγχο του φωτοβολταϊκού αντιστροφέα DC-AC και την παροχή των επικουρικών υπηρεσιών στο ηλεκτρικό δίκτυο έγινε χρήση της στρατηγική ελέγχου του τετραγώνου της τάσης DC-link. Τα αποτελέσματα των προσομοιώσεων έδειξαν ότι οι επικουρικές υπηρεσίες μπορούν να συμβάλλουν στην ευστάθεια του ηλεκτρικού δικτύου, στη βελτίωση της ποιότητας ισχύος που παρέχει το ηλεκτρικό δίκτυο και στη μείωση των απωλειών ισχύος του ηλεκτρικού δικτύου.
Make your Data and Software FAIR : AGU Guidance and Requirements
Creators: name: Erdmann, Christopher
name: Lyon, Laura
Publisher: name: Zenodo
Year: 2022
Subjects: FAIR
Data and Software Best Practices

description: What should be included and cited in your paper? Citing data and software you created for your research may seem odd and a little bit like self-citation. But Alas! This is exactly what is needed to get credit for the data and software you created for your research. Giving credit to not only your research outputs but also others’ software and data that you used in your research are important. These research outputs are valuable contributions to science and increase the possibility of higher numbers of citation for your published paper. In this session we will provide a checklist of what to cite in your paper as well as data and software management tools and practices that make sharing your data and software at the time of publication easier.

description: Presented online at Frontiers in Hydrology, June 24, 2022, as part of the Career Development Series https://www.agu.org/fihm This work is supported by Accelerating Open and FAIR Data Practices Across the Earth, Space, and Environmental Sciences: A Pilot with the NSF to Support Public Access to Research Data project funded by the National Science Foundation, Grant 2025364.
Методичні Аспекти Дизайнерської Підготовки  Майбутніх Учителів Технологій (Навчально-Методичний Посібник І.В. Савенка «Методика Навчання Вчителя Технологій Основ Дизайну»)
Creators: name: Валентина Оніпко
Publisher: name: Zenodo
Year: 2018

description: В умовах інтеграції українського суспільства у європейське співтовариство, його високотехнологічного розвитку, глобалізації вітчизняного освітнього простору вагомого значення  набуває  дизайнерська  освіта,  яка  належить  до  пріоритетних  напрямів професійної підготовки сучасних фахівців. Дизайнерська підготовка нині розглядається іміджетворчим інструментом суспільного та економічного поступу Української держави;  вона  ґрунтується  на  економічних,  виробничих,  технологічних,  естетичних  знаннях, проблемах і ситуаціях, а також на використанні набутих фахівцями компетентностей для їх вирішення
Time-dependent conformational analysis of ALK5-lumican complex in presence of graphene and graphene oxide employing molecular dynamics and MMPBSA calculation
Creators: name: Sridharan, Sindhiya
name: Nagarajan, Santhosh Kumar
name: Venugopal, Kathirvel
name: Venkatasubbu, G. Devanand
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Statistics
subject: FOS: Mathematics
subject: Computational Biology

description: Lumican, an extracellular matrix protein avails wound healing by binding to ALK5 membrane receptor (TGF-beta receptor I). Their interaction enables epithelialization and substantiates rejuvenation of injured tissue. To enrich permanence of ALK5-lumican interaction, we employed graphene and graphene oxide co-factors. Herein, this study explicates concomitancy of graphene and graphene oxide with ALK5-lumican. We performed an in silico approach involving molecular modelling, molecular docking, molecular dynamics for 200 ns, DSSP analysis and MMPBSA calculations. Results of molecular dynamics indicate cofactors influential in altering bioactive site of lumican than ALK5. Similarly, MMPBSA calculations unveiled binding energy of apoenzyme as −108.09 kcal/mol, holoenzyme (G) as −79.20 kcal/mol and holoenzyme (GO) as −114.33 kcal/mol. This concludes graphene oxide lucrative in enhancing binding energy of ALK5-lumican in holoenzyme (GO) via coil formation of Lum C13 domain. In contrast, graphene reduced binding energy of ALK5-lumican in holoenzyme (G) modifying Lum C13 into beta sheets. MMPBSA residual contribution analysis of Lum C13 residues revealed binding energy of −13.9 kcal/mol for apoenzyme, −6.8 kcal/mol for holoenzyme (G) and −19.5 kcal/mol for holoenzyme (GO). This supports coil formation propitious for better ALK5-Lum interaction. Highest SASA energy of −21.05 kcal/mol of holoenzyme (G) assures graphene reasonable for improved ALK5-lumican hydrophobicity. As per the motive of the study, graphene oxide enriches permanence of ALK5-lumican. This provides counsel for plausible exploitation of lumican and graphene oxide as targeted/nano drug delivery system to reinstate acute wounds, chronic wounds, corneal wounds, hypertrophic scars and keloids in near future. Communicated by Ramaswamy H. Sarma
Computer-aided design and experimental evaluation of a novel nucleosome binder
Creators: name: Giessmann, Robert T.
Publisher: name: Zenodo
Year: 2016

description: Die vorliegende Arbeit wurde in der Zeit von Juli 2015 bis Februar 2016 unter der Betreuung von Frau Jun.-Prof. Dr. Olalla Vázquez angefertigt.
 Vom Fachbereich Chemie der Philipps-Universität Marburg als Masterarbeit angenommen am 12. Februar 2016. Erstgutachter: Frau Jun.-Prof. Dr. Olalla Vázquez
 Zweitgutachter: Herr Dr. Peter Kolb