cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Asthma and posttraumatic stress symptoms 5 to 6 years following exposure to the World Trade Center terrorist attack
Creators: name: Farfel, Mark R.
name: Friedman, Stephen
name: Perlman, Sharon E.
name: Stellman, Steven D.
name: Walker, Deborah J.
name: Wu, David
name: Yu, Shengchao
name: Thorpe, Lorna E.
name: Brackbill, Robert M.
name: Ekenga, Christine C.
name: DiGrande, Laura
name: Hadler, James L.
Publisher: name: Columbia University
Year: 2009
Subjects: Epidemiology
Public health

description: Context. The World Trade Center Health Registry provides a unique opportunity to examine long-term health effects of a large-scale disaster. Objective. To examine risk factors for new asthma diagnoses and event-related posttraumatic stress (PTS) symptoms among exposed adults 5 to 6 years following exposure to the September 11, 2001, World Trade Center (WTC) terrorist attack. Design, Setting, and Participants. Longitudinal cohort study with wave 1 (W1) enrollment of 71 437 adults in 2003-2004, including rescue/recovery worker, lower Manhattan resident, lower Manhattan office worker, and passersby eligibility groups; 46 322 adults (68%) completed the wave 2 (W2) survey in 2006-2007. Main Outcome Measures. Self-reported diagnosed asthma following September 11; event-related current PTS symptoms indicative of probable posttraumatic stress disorder (PTSD), assessed using the PTSD Checklist (cutoff score >= 44). Results. Of W2 participants with no stated asthma history, 10.2% (95% confidence interval [CI], 9.9%-10.5%) reported new asthma diagnoses post-event. Intense dust cloud exposure on September 11 was a major contributor to new asthma diagnoses for all eligibility groups: for example, 19.1% vs 9.6% in those without exposure among rescue/recovery workers (adjusted odds ratio, 1.5 [95% CI, 1.4-1.7]). Asthma risk was highest among rescue/recovery workers on the WTC pile on September 11 (20.5% [95% CI, 19.0%-22.0%]). Persistent risks included working longer at the WTC site, not evacuating homes, and experiencing a heavy layer of dust in home or office. Of participants with no PTSD history, 23.8% (95% CI, 23.4%-24.2%) reported PTS symptoms at either W1(14.3%) orW2(19.1%). Nearly 10% (9.6% [95% CI, 9.3%-9.8%]) had PTS symptoms at both surveys, 4.7% (95% CI, 4.5%-4.9%) had PTS symptoms at W1 only, and 9.5% (95% CI, 9.3%-9.8%) had PTS symptoms at W2 only. At W2, passersby had the highest rate of PTS symptoms (23.2% [95% CI, 21.4%-25.0%]). Event-related loss of spouse or job was associated with PTS symptoms at W2. Conclusion. Acute and prolonged exposures were both associated with a large burden of asthma and PTS symptoms 5 to 6 years after the September 11 WTC attack.
Refroidissement passif de centre de données: étude expérimentale d'une boucle thermosyphon avec matériau à changement de phase
Creators: name: Sbaity, Ahmad Alamir
name: Louahlia, Hasna
name: Le Masson, Stéphane
Publisher: name: Société Française de Thermique
Year: 2020
Subjects: centre de données
refroidissement passif

description: Un centre de données abrite des installations informatiques telles que des serveurs, des routeurs, des commutateurs, etc…. Il traite et stocke des données numériques et est utilisé pour de nombreuses fonctions, dans les médias sociaux, les télécommunications et autres types de sociétés. La réduction de la consommation électrique des systèmes de refroidissement des centres de données est un défi majeur sur lequel les chercheurs travaillent pour créer des refroidisseurs innovants à faible consommation d'énergie. De nombreuses normes déterminent la température de fonctionnement pour garantir le fonctionnement normal du centre de données. Ces normes déterminent des métriques d'évaluation de l'efficacité énergétique d'un centre de données. Les chercheurs déterminent certains facteurs clés qui influent sur la performance énergétique d'un centre de données. L'un de ces facteurs est la température extérieure ou, d'autre manière, le climat de la zone géographique dans laquelle le centre de données est construit. Dans cet article, nous présentons les résultats d'une étude expérimentale montrant la capacité d'un système de refroidissement passif, ces tests montrent l'influence du MCP sur la capacité du boucle thermosyphon. De plus, nous présentons une validité du modèle TRNSYS, en comparant les résultats de ce modèle avec ceux issus de l'étude expérimentale.
Additional file 3 of Molecular detection of Helicobacter spp. and Fusobacterium gastrosuis in pigs and wild boars and its association with gastric histopathological alterations
Creators: name: Cortez Nunes, Francisco
name: Letra Mateus, Teresa
name: Taillieu, Emily
name: Teixeira, Sílvia
name: Carolino, Nuno
name: Rema, Alexandra
name: De Bruyckere, Sofie
name: Gärtner, Fátima
name: Haesebrouck, Freddy
name: Amorim, Irina
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3. BLAST identity percentage interval of the different Helicobacter spp. and F. gastrosuis sequences obtained.
title: Site‐selective substitution and resulting magnetism in arc‐melted perovskite ATiO₃₋δ (A = Ca, Sr, Ba)
Creators: name: Yoon, Songhak
name: Xie, Wenjie
name: Xiao, Xingxing
name: Checchia, Stefano
name: Coduri, Mauro
name: Schuetzenduebe, Peter
name: Widenmeyer, Marc
name: Ebbinghaus, Stefan G.
name: Balke, Benjamin
name: Weidenkaff, Anke
name: Schütz, Gisela
name: Son, Kwanghyo
Publisher: name: Wiley-Blackwell
Year: 2023

description: Magnetic properties in perovskite titanates ATiO₃₋δ (A = Ca, Sr, Ba) were investigated before and after arc melting. Crystal structure analysis was conducted by powder synchrotron X‐ray diffraction with Rietveld refinements. Quantitative chemical element analysis was carried out by X‐ray photoelectron spectroscopy. Magnetic measurements were conducted by vibrating sample magnetometer and X‐ray magnetic circular dichroism (XMCD). The magnetic properties are found to be affected by impurities of 3d elements such as Fe, Co, and Ni. Depending on the composition and crystal structure, the occupation of the magnetic ions in perovskite titanates is selectively varied, which is interpreted to be the origin of the different magnetic behaviors in arc‐melted perovskite titanates ATiO₃₋δ (A = Ca, Sr, Ba). In addition, both formation of oxygen vacancies and the reduction of Ti⁴⁺ to Ti³⁺ during arc‐melting also play a role as proven by XMCD. Nevertheless, preferential site occupation of magnetic impurities is dominant in the magnetic properties of arc‐melted perovskite ATiO₃₋δ (A = Ca, Sr, Ba).
Additional file 4 of Molecular detection of Helicobacter spp. and Fusobacterium gastrosuis in pigs and wild boars and its association with gastric histopathological alterations
Creators: name: Cortez Nunes, Francisco
name: Letra Mateus, Teresa
name: Taillieu, Emily
name: Teixeira, Sílvia
name: Carolino, Nuno
name: Rema, Alexandra
name: De Bruyckere, Sofie
name: Gärtner, Fátima
name: Haesebrouck, Freddy
name: Amorim, Irina
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 4. Number of Helicobacter spp. and F. gastrosuis DNA positive samples associated with gastritis score per pig gastric zone.
Understanding the role of cancer stemness in breast tumorigenesis
Creators: name: Shan, Naing Lin
Publisher: name: No Publisher Supplied
Year: 2020

description: Breast cancer is a heterogeneous disease; its high degrees of intra- and inter-tumoral diversity are attributable to the presence of a subset of tumor-initiating cells called breast cancer stem cells (BCSCs). BCSCs are endowed with self-renewal and differentiation potential, ultimately culminating in a hierarchically organized tumor with distinct degrees of differentiation and functions. Accumulating evidence suggests BCSCs play roles in tumor initiation, progression, metastasis, chemoresistance, and relapse. Thus, targeting BCSCs can be a promising therapeutic strategy for eradicating breast cancer. The goal of this study is to examine the significance of cancer stem cells in breast tumorigenesis and understand the mechanism of vitamin D compounds targeting cancer stem cell signaling pathways. Specifically, we seek to investigate (1) the effects of vitamin D-mediated inhibition of BCSCs in triple negative breast cancer (TNBC), (2) transcription factor-mediated regulation of breast cancer stemness, and (3) the transcriptomic signature regulated by vitamin D compounds in early breast cancer. In the pursuit of these goals, we utilize BCSC-enriching mammosphere culture, genetic modulation, and next-generation sequencing technologies in two experimental models of breast cancer: TNBC cells (SUM159), which are reported to harbor enriched cancer stem cell populations, and pre-invasive ductal carcinoma in situ cells (MCF10DCIS). In SUM159 cells, we observed vitamin D compounds (1,25-dihydroxyvitamin D3 and the Gemini vitamin D analog BXL0124) to inhibit mammosphere forming efficiency and self-renewal by downregulating markers of pluripotency and cancer stemness pathways. To understand the mechanism by which transcription factors control cancer stemness, we further studied octamer-binding transcription factor 4 (Oct4) as a potential factor in reprogramming BCSCs. We observed Oct4 overexpression to upregulate the CD44+/CD24- BCSC subpopulation, increasing expression of CD44 and the activated form of NFB, but with no significant changes in epithelial-mesenchymal transition markers and tumor formation in vivo. To understand whether breast cancer stem cells promote the progression of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC), along with vitamin D-mediated inhibition of this transition, we used RNA and DNA sequencing technologies to identify transcriptomic signatures in MCF10DCIS mammospheres. Our study revealed a global view of genes differentially regulated by vitamin D compounds, along with genes potentially involved in breast cancer stemness and progression. Ingenuity Pathway Analysis identified the TP63-VDR axis as a plausible target that can be explored for inhibition of DCIS transition to IDC. Collectively, these findings suggest a role for vitamin D as a potential preventive agent in targeting cancer stemness and breast cancer progression.
SAP Speaks PDDL: Exploiting a Software-Engineering Model for Planning in Business Process Management
Creators: name: Hoffman, Joerg
name: Weber, Ingo
name: Kraft, Frank Michael
Publisher: name: arXiv
Year: 2014
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Planning is concerned with the automated solution of action sequencing problems described in declarative languages giving the action preconditions and effects. One important application area for such technology is the creation of new processes in Business Process Management (BPM), which is essential in an ever more dynamic business environment. A major obstacle for the application of Planning in this area lies in the modeling. Obtaining a suitable model to plan with -- ideally a description in PDDL, the most commonly used planning language -- is often prohibitively complicated and/or costly. Our core observation in this work is that this problem can be ameliorated by leveraging synergies with model-based software development. Our application at SAP, one of the leading vendors of enterprise software, demonstrates that even one-to-one model re-use is possible. The model in question is called Status and Action Management (SAM). It describes the behavior of Business Objects (BO), i.e., large-scale data structures, at a level of abstraction corresponding to the language of business experts. SAM covers more than 400 kinds of BOs, each of which is described in terms of a set of status variables and how their values are required for, and affected by, processing steps (actions) that are atomic from a business perspective. SAM was developed by SAP as part of a major model-based software engineering effort. We show herein that one can use this same model for planning, thus obtaining a BPM planning application that incurs no modeling overhead at all. We compile SAM into a variant of PDDL, and adapt an off-the-shelf planner to solve this kind of problem. Thanks to the resulting technology, business experts may create new processes simply by specifying the desired behavior in terms of status variable value changes: effectively, by describing the process in their own language.
Additional file 1 of Mobile group I introns at nuclear rDNA position L2066 harbor sense and antisense homing endonuclease genes intervened by spliceosomal introns
Creators: name: Lian, Kjersti
name: Furulund, Betty M. N.
name: Tveita, Anders A.
name: Haugen, Peik
name: Johansen, Steinar D.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 60506 Virology

description: Additional file 1: Figure S1. Consensus secondary structure diagrams of L2066 group I introns in myxomycetes and ascomycetes. a) Consensus structure in myxomycetes based on ca 250 nucleotide positions in the catalytic core common among introns from 16 taxa (see Table 1). Sequence size variations are noted in most peripheral regions, and homing endonuclease genes (HEGs) are found as P9 extensions. P1-P10 and P13, paired RNA segments; 5′ SS and 3′SS, exon-intron splice sites. Invariant nucleotide positions are shown as red uppercase letters. Black uppercase letter, > 90% conservation; lowercase letters, ≥ 50% conservation; filled circles, < 50% conservation. b) Consensus structure in ascomycetes based on ca 260 nucleotide positions in the catalytic core common among introns from 18 taxa (see Table 1).
Etude expérimentale des performances thermiques d'une paroi ventilée bioclimatique
Creators: name: Sukamto, Dwinanto
name: Gloriant, Francois
name: Siroux, Monica
Publisher: name: Société Française de Thermique
Year: 2020
Subjects: Bâtiment
Paroi ventilée
convection
caractérisation expérimentale

description: Les orientations politiques actuelles imposent le bâtiment à énergie zéro (NZEB) comme nouveau standard de la construction neuve pour 2020. Par ailleurs, dans le domaine de la réhabilitation énergétique des bâtiments existants, la recherche de solutions pour la rénovation est un sujet fondamental. L'enjeu de cette démarche est l'efficacité énergétique des bâtiments pour la lutte contre le changement climatique et un des moyens pour y parvenir ce sont des parois innovantes bioclimatiques, qui sont la base des économies d'énergie dans le bâtiment de demain. Les travaux de cette communication s'inscrivent dans ce cadre et visent à caractériser les performances thermiques d'une paroi ventilée bioclimatique. Un dispositif expérimental original a été mis en place permettant ainsi l'étude expérimentale d'une paroi ventilée bioclimatique. Des résultats expérimentaux ont été réalisés dans une enceinte climatique et nous ont permis de quantifier le flux de chaleur échangé à travers la paroi ventilée bioclimatique. Par ailleurs, une étude paramétrique a permis de mettre en évidence l'influence de la dimension de la cavité et du débit de l'écoulement sur le transfert thermique.
Finslerian perturbation for the $Λ$CDM model
Creators: name: Li, Xin
name: Wang, Sai
name: Chang, Zhe
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We present Finslerian perturbation for the $Λ$CDM model, which breaks the isotropic symmetry of the universe. The analysis on the Killing vectors shows that the Randers-Finsler spacetime breaks the isotropic symmetry even if the scalar perturbations of the FRW metric vanish. In Randers-Finsler spacetime, the modified geodesic equation deduces a modified Boltzmann equation. We propose a perturbational version of the gravitational field equation in Randers-Finsler spacetime, where we have omitted the curvature tensor that does not belong to the base space of the tangent bundle. The gravitational field equations for the gravitational wave are also presented. The primordial power spectrum of the gravitational wave is investigated. We show that the primordial power spectrum for super-horizon perturbations is unchanged. For sub-horizon perturbations, however, the power spectrum is modified.
description: 17 pages
MPEC 2023-V87 : DAILY ORBIT UPDATE (2023 November 7)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies
Creators: name: Bushman, Frederic D.
name: Fernandes, Jason
name: D'Orso, Ivan
name: Malani, Nirav
name: Zhou, Honglin
name: Hazuda, Daria J.
name: Espeseth, Amy S.
name: Konig, Renate
name: Bandyopadhyay, Sourav
name: Ideker, Trey
name: Cagney, Gerard
name: Diamond, Tracy L.
name: Goff, Stephen P.
name: Krogan, Nevan J.
name: Frankel, Alan D.
name: Young, John A. T.
name: Chanda, Sumit K.
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Pathology
subject: Genetics
subject: FOS: Biological sciences
subject: Cytology

description: We have analyzed host cell genes linked to HIV replication that were identified in nine genome-wide studies, including three independent siRNA screens. Overlaps among the siRNA screens were very modest (less than 7% for any pairwise combination), and similarly, only modest overlaps were seen in pairwise comparisons with other types of genome-wide studies. Combining all genes from the genome-wide studies together with genes reported in the literature to affect HIV yields 2,410 protein-coding genes, or fully 9.5% of all human genes (though of course some of these are false positive calls). Here we report an “encyclopedia” of all overlaps between studies (available at http://www.hostpathogen.org), which yielded a more extensively corroborated set of host factors assisting HIV replication. We used these genes to calculate refined networks that specify cellular subsystems recruited by HIV to assist in replication, and present additional analysis specifying host cell genes that are attractive as potential therapeutic targets.
Additional file 5 of Molecular detection of Helicobacter spp. and Fusobacterium gastrosuis in pigs and wild boars and its association with gastric histopathological alterations
Creators: name: Cortez Nunes, Francisco
name: Letra Mateus, Teresa
name: Taillieu, Emily
name: Teixeira, Sílvia
name: Carolino, Nuno
name: Rema, Alexandra
name: De Bruyckere, Sofie
name: Gärtner, Fátima
name: Haesebrouck, Freddy
name: Amorim, Irina
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 5. Number of Helicobacter spp. and F. gastrosuis DNA positive samples associated with gastritis score per wild boar’s gastric zone.
The Drosophila snr1 and brm Proteins are Related to Yeast SWI/SNF Proteins and are Components of a Large Protein Complex
Creators: name: Dingwall, A. K.
name: Beek, S. J.
name: McCallum, C. M.
name: Tamkun, J. W.
name: Kalpana, G. V.
name: Goff, Stephen P.
name: Scott, M. P.
Publisher: name: Columbia University
Year: 1995
Subjects: Genetic transcription--Regulation
Molecular biology
Cytology

description: During most of Drosophila development the regulation of homeotic gene transcription is controlled by two groups of regulatory genes, the trithorax group of activators and the Polycomb group of repressors. brahma (brm), a member of the trithorax group, encodes a protein related to the yeast SWI2/SNF2 protein, a subunit of a protein complex that assists sequence-specific activator proteins by alleviating the repressive effects of chromatin. To learn more about the molecular mechanisms underlying the regulation of homeotic gene transcription, we have investigated whether a similar complex exists in flies. We identified the Drosophila snr1 gene, a potential homologue of the yeast SNF5 gene that encodes a subunit of the yeast SWI/SNF complex. The snr1 gene is essential and genetically interacts with brm and trithorax (trx), suggesting cooperation in regulating homeotic gene transcription. The spatial and temporal patterns of expression of snr1 are similar to those of brm. The snr1 and brm proteins are present in a large (> 2 x 10(6) Da) complex, and they co-immunoprecipitate from Drosophila extracts. These findings provide direct evidence for conservation of the SWI/SNF complex in higher eucaryotes and suggest that the Drosophila brm/snr1 complex plays an important role in maintaining homeotic gene transcription during development by counteracting the repressive effects of chromatin.
Variability and vertical structure of gaseous air quality indicators above urban areas: IAGOS in-situ profiling of nitrogen oxides, ozone, and carbon monoxide
Creators: name: Mahnke, Christoph
name: Bundke, Ulrich
name: Houben, Norbert
name: Blomel, Torben
name: Nédélec, Philippe
name: Thouret, Valérie
name: Clark, Hannah
name: Petzold, Andreas
Publisher: name: Forschungzentrum Jülich
Year: 2023

description: EGU General Assembly 2023, Vienna, Austria, 23 Apr 2023 - 28 Apr 2023; doi:10.5194/egusphere-egu23-5280
Refroidissement radiatif en laboratoire pour rosée naturelle
Creators: name: Trosseille, Joachim
name: Royon, Laurent
name: Mongruel, Anne
name: Beysens, Daniel
Publisher: name: Société Française de Thermique
Year: 2020
Subjects: refroidissement radiatif
rosée
goutte
émissivité

description: Nous présentons un dispositif original développé pour reproduire en laboratoire le phénomène de rosée sur tous substrats, notamment ceux (insectes, végétaux…) qu'il est difficile, voire impossible à de refroidir par contact. Sur la base d'un échange radiatif avec une source froide, un refroidissement d'au moins $50 \unit{W.m^{-2}}$ est obtenu sur la surface collectrice, comparable à celui mis en jeu dans le phénomène naturel de la rosée. La formation et la croissance des gouttes de rosée obtenues avec ce dispositif sont comparées à celles obtenues par refroidissement par contact de la surface collectrice (cellule à effet Peltier). L'influence des propriétés radiatives et de mouillage de la surface collectrice sur le rendement de la production de rosée (taux de condensation) est également étudiée et discutée.
Role of Gas6 in Erythropoiesis and Anemia in Mice
Creators: name: Angelillo-Scherrer, Anne
name: Burnier, Laurent
name: Lambrechts, Diether
name: Fish, Richard J.
name: Tjwa, Marc
name: Plaisance, Stéphane
name: Sugamele, Rocco
name: DeMol, Maria
name: Martinez-Soria, Eduardo
name: Maxwell, Patrick H.
name: Lemke, Greg
name: Goff, Stephen P.
name: Matsushima, Glenn K.
name: Earp, H. Shelton
name: Chanson, Marc
name: Collen, Désiré
name: Izui, Shozo
name: Schapira, Marc
name: Conway, Edward M.
name: Carmeliet, Peter
Publisher: name: Columbia University
Year: 2008
Subjects: Cytology
Medicine

description: Many patients with anemia fail to respond to treatment with erythropoietin (Epo), a commonly used hormone that stimulates erythroid progenitor production and maturation by human BM or by murine spleen. The protein product of growth arrest–specific gene 6 (Gas6) is important for cell survival across several cell types, but its precise physiological role remains largely enigmatic. Here, we report that murine erythroblasts released Gas6 in response to Epo and that Gas6 enhanced Epo receptor signaling by activating the serine-threonine kinase Akt in these cells. In the absence of Gas6, erythroid progenitors and erythroblasts were hyporesponsive to the survival activity of Epo and failed to restore hematocrit levels in response to anemia. In addition, Gas6 may influence erythropoiesis via paracrine erythroblast-independent mechanisms involving macrophages. When mice with acute anemia were treated with Gas6, the protein normalized hematocrit levels without causing undesired erythrocytosis. In a transgenic mouse model of chronic anemia caused by insufficient Epo production, Gas6 synergized with Epo in restoring hematocrit levels. These findings may have implications for the treatment of patients with anemia who fail to adequately respond to Epo.
Migraine and tension-type headache in Germany. Prevalence and disease severity from the BURDEN 2020 Burden of Disease Study
Creators: name: Porst, Michael
name: Wengler, Annelene
name: Leddin, Janko
name: Neuhauser, Hanne
name: Katsarava, Zaza
name: Von Der Lippe, Elena
name: Anton, Aline
name: Ziese, Thomas
name: Rommel, Alexander
Publisher: name: Robert Koch-Institut
Year: 2020
Subjects: subject: Migraine
subject: Tension-Type Headache
subject: Comorbidities
subject: Burden of Disease
subject: 610 Medizin und Gesundheit

description: Headache disorders are widespread among women and men in Germany and are primarily associated with restrictions on quality of life. The two most common types of headache disorders are migraine and tension-type headache. In order to gain valid estimates of the prevalence of these conditions, a cross-sectional telephone-based survey was conducted among adults in Germany (N=5,009) between October 2019 and March 2020. The frequency, duration, the characteristics and comorbidities associated with headache were measured using the diagnostic criteria defined in the International Classification of Headache Disorders. 57.5% of women and 44.4% of men in Germany stated that they had had a headache in the last twelve months. 14.8% of women and 6.0% of men meet all of the diagnostic criteria for migraine. Tensiontype headache affects 10.3% of women and 6.5% of men. Migraine and tension-type headache are predominantly found among people of working age and steadily decrease with age. Migraine is often accompanied by comorbidities such as depressive symptoms and anxiety disorders. People affected by headache disorders tend to receive very little professional medical care, with only a minority seeking treatment within a year. These results provide a comprehensive picture of the population-related impact of headache disorders and are used in the BURDEN 2020 study to quantify key indicators for burden of disease assessment.
Extraordinary absorption of sound in porous lamella-crystals
Creators: name: Christensen, J.
name: Romero-García, V.
name: Picó, R.
name: Cebrecos, A.
name: de Abajo, F. J. García
name: Mortensen, N. A.
name: Willatzen, M.
name: Sánchez-Morcillo, V. J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present the design of a structured material supporting complete absorption of sound with a broadband response and functional for any direction of incident radiation. The structure which is fabricated out of porous lamellas is arranged into a low-density crystal and backed by a reflecting support. Experimental measurements show that strong all-angle sound absorption with almost zero reflectance takes place for a frequency range exceeding two octaves. We demonstrate that lowering the crystal filling fraction increases the wave interaction time and is responsible for the enhancement of intrinsic material dissipation, making the system more absorptive with less material.
Simulation numérique de l'écoulement dans un éjecteur supersonique
Creators: name: Gritli, Souhir
name: Lepiller, Valérie
name: Elakhdar, Mouna
name: Nahdi, Ezzedine
name: Desevaux, Philippe
Publisher: name: Société Française de Thermique
Year: 2020
Subjects: éjecteur
turbulence
chocs
simulation numérique

description: Ce travail présente une étude sur l'analyse de l'écoulement au sein de l'éjecteur et plus particulièrement du processus de recompression par chocs qui prend place le long de la tuyère secondaire. Les simulations numériques sont réalisées à l'aide du logiciel de CFD ANSYS- FLUENT. Les deux modes de fonctionnement de l'éjecteur (sans et avec flux induit) sont étudiés pour différentes valeurs de la pression génératrice primaire P1 comprises entre 2 et 5 bar. Dans un premier temps, les distributions axiales de la pression sont analysées. Ensuite, la structure de chocs est visualisée afin d'appuyer certaines conclusions. Des tests sur le choix du modèle de turbulence le mieux adapté en termes de représentation correcte des phénomènes physiques ont été réalisés. Il a été montré que le modèle k-oméga-SST semblait le mieux adapté pour prédire la structure de choc. Les résultats numériques obtenus à partir des simulations 2D axisymétriques sont très encourageants. Les performances de l'éjecteur en termes d'aspiration et d'entrainement de flux secondaire ont été déterminées numériquement et comparées aux données expérimentales. L'influence de la distance entre la section de sortie de la tuyère primaire et la section d'entrée de la chambre de mélange de l'éjecteur (facteur géométrique NXP) sur les performances de l'éjecteur a été ensuite analysée.
Additional file 2 of Mobile group I introns at nuclear rDNA position L2066 harbor sense and antisense homing endonuclease genes intervened by spliceosomal introns
Creators: name: Lian, Kjersti
name: Furulund, Betty M. N.
name: Tveita, Anders A.
name: Haugen, Peik
name: Johansen, Steinar D.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 60506 Virology

description: Additional file 2: Figure S2. Sequence alignment of 186 core structure nucleotides of myxomycete and ascomycete L2066 group I introns. Secondary structure paired segments (P1-P8) are shown above the alignment, and key segments are colour coded. Intron taxa sequences are indicated by species name abbreviations and GeneBank accession numbers.
title: Investigation of pressure and temperature gradient in four-phase flow in a complex horizontal pipeline
Creators: name: Odan, Mohamed Abdalla
Publisher: name: Memorial University of Newfoundland
Year: 2022

description: The oil and gas (O&G) industry uses multi-phase and multi-component pipeline flows to move product from one site to another or to different areas within the same site. In extreme environments, such as offshore or the Arctic, the development of four-phase flows in a complex pipeline can bring even more challenges to the project. Jumpers and bends need to be able to is to withstand pressure drops and hydrodynamic loads from internal multi-phase flows and the current, respectively. The study outlines the development of an experiment to investigate of pressure and temperature gradients in four-phase flows in a complex pipeline. Due to the excessive temperatures and pressures of the oil transport pipeline system, the main pipes include shorter pipes (bends and jumpers) that are attached to the manifold at the pipeline. These shorter pipes are used to enable expandability and prevent system failure. The present work examines the practicality of applying a system of four-phase, four-fluid flows for transporting a multi-phase flow (sand, water, gas, and oil) along a flow loop horizontal pipeline with many multiple bends and jumpers. This experimental set-up can be used for investigating a wide variety of multi-phase flow problems considered in the this research. As a means to precisely measure and predict the characteristics of thermo- and hydro-dynamic multi-component mixtures, models representing the multi-phase behavior and equilibrium phase are created and tested. Additionally, the study looks at heat transfer, mass, and momentum in both the flow and the pipeline walls, and offers equations to describe their interrelationships. Another focus of this research is to obtain a Computational Fluid Dynamics (CFD) investigation of multi-phase flow phenomena in order to characterize the impact of pressure gradients and flow regimes due to various types of phase flow techniques used in the petroleum industry and in horizontal pipelines. The results of this thesis offer fundamental and practical guidance for the analysis and design of flow loop pipeline multi-phase flow systems and devices incorporating four-phase flows (sand, water, gas, and oil) through a flow loop pipeline. The novel results were obtained with carefully controlled flow loop pipeline and volume fractions, which show a significant impact on temperature and pressure drops. Dimensionless numbers in fluid mechanics and pressure drop results show good agreement with the experimental data. Further, the experimental and modeling approach of this thesis makes a unique contribution to the O&G field and to the design of transport pipelines for processing four-phase flows that include bends and jumpers.
Quantum disorder and local modes of the fully-frustrated transverse field Ising model on a diamond chain
Creators: name: Coester, K.
name: Malitz, W.
name: Fey, S.
name: Schmidt, K. P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate the transverse field Ising model on a diamond chain using series expansions about the high-field limit and exact diagonalizations. For the unfrustrated case we accurately determine the quantum critical point and its expected 2d Ising universality separating the polarized and the Z2 symmetry broken phase. In contrast, we find strong evidences for a disorder by disorder scenario for the fully-frustrated transverse field Ising model, i.e. except for the pure Ising model, having an extensive number of ground states, the system is always in a quantum disordered polarized phase. The low-energy excitations in this polarized phase are understood in terms of exact local modes of the model. Furthermore, an effective low-energy description for an infinitesimal transverse field allows to pinpoint the quantum disordered nature of the ground state via mapping to an effective transverse field Ising chain and to determine the induced gap to the elementary effective domain wall excitation very accurately.
description: 7 pages, 5 figures
Caractérisation du comportement thermique des batteries Li-ion en vue d'une gestion optimale passive
Creators: name: El Idi, Mohamed Moussa
name: Karkri, Mustapha
name: Abdou Tankari, Mahamadou
Publisher: name: Société Française de Thermique
Year: 2020
Subjects: véhicule électrique
batteries Li-ion
gestion thermique
matériaux à changement de phase
stockage par chaleur latente
système passif

description: Le conditionnement optimal des batteries Li-ion est indispensable pour leur assurer une meilleure performance, une autonomie et une durée de vie optimale. Les méthodes classiques se basent sur un contrôle thermique forcé ou naturel souvent coûteux et encombrant avec une efficacité limitée. L'utilisation des matériaux à changement de phase (MCP), de manière passive, représente une alternative intéressante. Les MCP ont la capacité de stocker de l'énergie thermique dans des volumes réduits. Cependant, les MCPs présentent des inconvénients comme la difficulté de décharger l'énergie thermique stockée, ce qui limite l'aptitude du système au cyclage, ou encore leur conductivité thermique peu élevée qui limite les capacités d'échanges. Les mousses métalliques à grande porosité apparaissent comme une solution attractive qui peut améliorer la conductivité thermique effective sans réduire la densité de stockage. Dans ce travail, la gestion thermique passive des batteries Li-ion par un composite MCP/Mouse métallique est étudiée Et le système caractérisé au moyen d'un nouveau dispositif expérimental développé en laboratoire. Un modèle numérique qui permet de prédire le comportement thermique d'une cellule Li-ion est proposé et validé par comparaison à des résultats expérimentaux. Un accent particulier est mis sur l'optimisation de la quantité du MCP utilisé et la durée indispensable pour évacuer la quantité de chaleur stockée dans le MCP.
title: Dislocation‐tuned electrical conductivity in solid electrolytes (9YSZ): A micro‐mechanical approach
Creators: name: Muhammad, Qaisar Khushi
name: Valderrama, Marcela
name: Yue, Mengkun
name: Opitz, Alexander Karl
name: Taibl, Stefanie
name: Siebenhofer, Matthäus
name: Bruder, Enrico
name: Fleig, Jürgen
name: Fang, Xufei
name: Frömling, Till
Publisher: name: Wiley-Blackwell
Year: 2023

description: Tailoring the electrical conductivity of functional ceramics by introducing dislocations is a comparatively recent research focus, and its merits were demonstrated through mechanical means. Especially bulk deformation at high temperatures is suggested to be a promising method to introduce a high dislocation density. So far, however, controlling dislocation generation and their annihilation remains difficult. Although deforming ceramics generate dislocations on multiple length scales, dislocation annihilation at the same time appears to be the bottleneck to use the full potential of dislocations‐tailoring the electrical conductivity. Here, we demonstrate the control over these aspects using a micromechanical approach on yttria‐stabilized zirconia ‐ YSZ. Targeted indentation well below the dislocation annihilation temperature resulted in extremely dense dislocation networks, visualized by chemical etching and electron channeling contrast imaging. Microcontact‐impedance measurements helped evaluate the electrical response of operating individual slip systems. A significant conductivity enhancement is revealed in dislocation‐rich regions compared to pristine ones in fully stabilized YSZ. This enhancement is mainly attributed to oxygen ionic conductivity. Thus, the possibility of increasing the conductivity is illustrated and provides a prospect to transfer the merits of dislocation‐tuned electrical conductivity to solid oxygen electrolytes.
Overexpression of Fasciculation and Elongation Protein ζ-1 (FEZ1) Induces a Post-entry Block to Retroviruses in Cultured Cells
Creators: name: Naghavi, Mojgan H.
name: Hatziioannou, Theodora
name: Gao, Guangxia
name: Goff, Stephen P.
Publisher: name: Columbia University
Year: 2005
Subjects: subject: Molecular biology
subject: Virology
subject: Genetics
subject: FOS: Biological sciences

description: Two mutant Rat2 fibroblast cell lines, R3-2 and R4-7, have been previously isolated by a selection for retrovirus resistance. We have now further analyzed the basis of the block to retroviral infection in the R3-2 line. Using Affymetrix GeneChip analysis, several genes were identified as differentially expressed in the mutant R3-2 line compared with the wild-type cells. One of the candidate gene products, FEZ1 (fasciculation and elongation protein ζ-1), a protein kinase C (PKC)ζ-interacting protein homologous to the Caenorhabditis elegans synaptic transport protein UNC-76, was found to be up-regulated >30-fold in the resistant R3-2 line. FEZ1 overexpression in Rat2 cells conferred a potent resistance to infection by genetically marked retroviruses, and the degree of retroviral resistance in both Rat2 fibroblasts and 293T cells tightly correlated with the expression level of FEZ1 transcripts. FEZ1-overexpressing Rat2 cells showed a similar phenotype to that of the mutant R3-2 line: Infection resulted in normal viral DNA synthesis but a reduction in the formation of circular DNA, indicating a block after reverse transcription but before nuclear entry. Partial knockdown of FEZ1 expression in R3-2 by RNA interference (RNAi) significantly reduced the resistance of this line to infection. Thus, our data suggest that FEZ1 overexpression is sufficient to explain the resistant phenotype of R3-2 cells and identify FEZ1 as a new gene capable of causing retrovirus resistance.
Identifying and analyzing amorphization in boron-rich boron carbides
Creators: name: Schaefer, Mark Christopher
Publisher: name: No Publisher Supplied
Year: 2020

description: Boron carbide is a ceramic material known for its high hardness and low density. These properties make it an ideal material to be used in armor materials. However, when subjected to shock-loading experiments, boron carbide does not perform as expected. Rather than undergo a work-hardening mechanism past a critical shock-loading point, as is the case in similar ceramic materials like silicon carbide, boron carbide suddenly fails. This abrupt failure under dynamic loading has been attributed to “amorphization,” the appearance of nanometer-sized amorphous bands that limit the boron carbides ballistic performance.Much work has been done to understand amorphization and elucidate its atomistic mechanism. These attempts to identify the peak point in boron carbide lead to several suggestions to fix boron carbides amorphous behavior as a means to improve its ballistic performance. One such alternative theorized doping the boron carbide structure with boron and silicon. Much work has been done already in understanding silicon-doped boron carbide mitigating amorphization, but little has been done in understanding boron-rich boron carbides effect on amorphous behavior. While several studies have been carried out to process boron-rich boron carbides and study their mechanical properties, no work has been experimentally carried out in understanding amorphization in these materials.In this dissertation, boron-rich boron carbides are studied with respect to amorphization, something previously overlooked in the literature. This work is done with the intention of supporting and validating models that suggest boron-rich boron carbides can mitigate amorphization. Methods will be developed to accurately assess and quantify the degree of amorphization in boron carbides that span the materials homogeneity range. Indentation was used as a means to activate stress-induced amorphization in samples. Raman spectroscopy will be heavily utilized in this work as a means to quickly probe samples for amorphization in a non-destructive manner.Additionally, the use of Raman spectroscopy allows for various in situ measurements to be carried out at elevated temperatures and large pressures. These factors are critical in simulating ballistic impact parameters in the laboratory and studying these in situ can help determine the evolution of the amorphous phase as these parameters are varied.Amorphization mitigation in boron-rich boron carbides was determined through Raman spectroscopy quantification methods developed in this thesis and were also validated through TEM imaging. Further, in situ experiments were carried out at large pressures that determined critical onset pressure conditions to induce amorphization in doped samples. This allowed for comparison between amorphization mechanisms between samples of differing compositions.
Strictly positive solutions for one-dimensional nonlinear problems involving the p-Laplacian
Creators: name: Kaufmann, Uriel
name: Medri, Ivan
Publisher: name: arXiv
Year: 2013
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 34B15, 34B18, 35J25, 35J61

description: Let $Ω$ be a bounded open interval, and let $p>1$ and $q\in\left(0,p-1\right) $. Let $m\in L^{p^{\prime}}\left(Ω\right) $ and $0\leq c\in L^{\infty}\left(Ω\right) $. We study existence of strictly positive solutions for elliptic problems of the form $-\left(\left\| u^{\prime}\right\|^{p-2}u^{\prime}\right) ^{\prime}+c\left(x\right) u^{p-1}=m\left(x\right) u^{q}$ in $Ω$, $u=0$ on $\partialΩ$. We mention that our results are new even in the case $c\equiv0$.
description: To appear in Bulletin of the Australian Mathematical Society
Estimation de diagrammes de phases de systèmes binaires par thermographie infrarouge
Creators: name: Mailhé, Clément
name: Duquesne, Marie
Publisher: name: Société Française de Thermique
Year: 2020
Subjects: Screening de matériaux
diagrammes et transitions de phases
thermographie infrarouge
calorimétrie différentielle à balayage
modélisation thermodynamique

description: Le diagramme de phases, outil primordial en sciences des matériaux, sert à la synthèse, la compréhension des comportements et des propriétés macroscopiques des matériaux. De nombreuses techniques expérimentales existent pour déterminer un diagramme de phases d'un système binaire mais elles sont chronophages. La méthode IRT (Thermographie InfraRouge) permet d'établir rapidement un diagramme de phase préliminaire pour accélérer l'étape de "screening", qui précède souvent le développement d'un nouveau matériau. Dans ce travail, nous présentons la méthode utilisée et les résultats obtenus pour les diagrammes de phases de systèmes binaires de complexité croissante (transitions eutectique, péritectique etc.). Nos résultats sont comparés aux résultats obtenus dans la littérature, par mesure de calorimétrie différentielle à balayage (DSC) et grâce à un modèle thermodynamique.
Plan-based Policies for Efficient Multiple Battery Load Management
Creators: name: Fox, Maria
name: Long, Derek
name: Magazzeni, Daniele
Publisher: name: arXiv
Year: 2014
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Efficient use of multiple batteries is a practical problem with wide and growing application. The problem can be cast as a planning problem under uncertainty. We describe the approach we have adopted to modelling and solving this problem, seen as a Markov Decision Problem, building effective policies for battery switching in the face of stochastic load profiles. Our solution exploits and adapts several existing techniques: planning for deterministic mixed discrete-continuous problems and Monte Carlo sampling for policy learning. The paper describes the development of planning techniques to allow solution of the non-linear continuous dynamic models capturing the battery behaviours. This approach depends on carefully handled discretisation of the temporal dimension. The construction of policies is performed using a classification approach and this idea offers opportunities for wider exploitation in other problems. The approach and its generality are described in the paper. Application of the approach leads to construction of policies that, in simulation, significantly outperform those that are currently in use and the best published solutions to the battery management problem. We achieve solutions that achieve more than 99% efficiency in simulation compared with the theoretical limit and do so with far fewer battery switches than existing policies. Behaviour of physical batteries does not exactly match the simulated models for many reasons, so to confirm that our theoretical results can lead to real measured improvements in performance we also conduct and report experiments using a physical test system. These results demonstrate that we can obtain 5%-15% improvement in lifetimes in the case of a two battery system.