cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of femoral head size and surgical approach on risk of revision for dislocation after total hip arthroplasty
Creators: name: Zijlstra, Wierd P
name: Hartog, Bas De
name: Steenbergen, Liza N Van
name: B Willem Scheurs
name: Nelissen, Rob G H H
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Background and purpose — Recurrent dislocation is the commonest cause of early revision of a total hip arthropasty (THA). We examined the effect of femoral head size and surgical approach on revision rate for dislocation, and for other reasons, after total hip arthroplasty (THA). Patients and methods — We analyzed data on 166,231 primary THAs and 3,754 subsequent revision THAs performed between 2007 and 2015, registered in the Dutch Arthroplasty Register (LROI). Revision rate for dislocation, and for all other causes, were calculated by competing-risk analysis at 6-year follow-up. Multivariable Cox proportional hazard regression ratios (HRs) were used for comparisons. Results — Posterolateral approach was associated with higher dislocation revision risk (HR =1) than straight lateral, anterolateral, and anterior approaches (HR =0.5–0.6). However, the risk of revision for all other reasons (especially stem loosening) was higher with anterior and anterolateral approaches (HR =1.2) and lowest with posterolateral approach (HR =1). For all approaches, 32-mm heads reduced the risk of revision for dislocation compared to 22- to 28-mm heads (HR =1 and 1.6, respectively), while the risk of revision for other causes remained unchanged. 36-mm heads increasingly reduced the risk of revision for dislocation but only with the posterolateral approach (HR =0.6), while the risk of revision for other reasons was unchanged. With the anterior approach, 36-mm heads increased the risk of revision for other reasons (HR =1.5). Interpretation — Compared to the posterolateral approach, direct anterior and anterolateral approaches reduce the risk of revision for dislocation, but at the cost of more stem revisions and other revisions. For all approaches, there is benefit in using 32-mm heads instead of 22- to 28-mm heads. For the posterolateral approach, 36-mm heads can safely further reduce the risk of revision for dislocation.
Rheological Properties of Lyotropic Liquid Crystals Encapsulating Curcumin
Creators: name: Wang, Xue
name: Wang, Zhongni
name: Zhao, Xin
name: Zhang, Li
name: Fan, Jun
Publisher: name: Taylor & Francis
Year: 2016
Subjects: Biophysics
Space Science
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: This study constructed new curcumin-loaded lyotropic liquid crystals containing pharmaceutically accepted oil, ethyl oleate (EtOL). Three liquid crystalline phases including lamellar, hexagonal and cubic phases were identified by means of the polarized optical microscopy and rheology method. By analyzing the shear viscosity (η0.1), the viscosity of curcumin-liquid crystals is smaller than those without curcumin. Dynamic rheological results show that: Dissolved curcumin in EtOL can make the elastic modulus of hexagonal and cubic phase increase compared with that without curcumin, while the elastic modulus of lamellar phase decreases. Dissolved curcumin in Brij 97 can lead to the decreasing of the elastic modulus for cubic and lamellar phases, whereas it has little influence on hexagonal phase. When the curcumin is solubilized in both EtOL and Brij 97, the elastic modus of hexagonal phase increase, the elastic modus of lamellar and cubic phases decrease compared with that without curcumin. Furthermore, three temperature turning points were identified by the change in the slope oftanδ (G″/G′) for curcumin-hexagonal liquid crystal. These studies might be a help to study the storage of drug carrier and in vitro release properties of lyotropic liquid crystals containing curcumin.
Enhanced poly(L-malic acid) production from pretreated cane molasses by Aureobasidium pullulans in fed-batch fermentation
Creators: name: Xia, Jun
name: Xu, Jiaxing
name: Hu, Lei
name: Liu, Xiaoyan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Poly(L-malic acid) (PMA) is a natural polyester with many attractive properties for biomedical application. However, the cost of PMA production is high when glucose is used as a carbon source. To solve this problem, cane molasses as a low-cost feedstock was applied for the production of PMA. Six pretreatment methods were applied to cane molasses before fermentation. Pretreatment with combined tricalcium phosphate, potassium ferrocyanide, and sulfuric acid (TPFSA) removed significant amounts of metal ions from cane molasses. The PMA concentration increased from 5.4 g/L (untreated molasses) to 36.9 g/L (TPFSA-pretreated molasses) after fermentation in shake flasks. A fed-batch fermentation strategy was then developed. In this method, TPFSA-pretreated cane molasses solution was continuously fed into the fermentor to maintain the total sugar concentration at 20 g/L. This technique generated approximately 95.4 g/L PMA with a productivity of 0.57 g/L/hr. The present study indicated that fed-batch fermentation using pretreated cane molasses is a feasible technique for producing high amounts of PMA.
Enhanced poly(L-malic acid) production from pretreated cane molasses by Aureobasidium pullulans in fed-batch fermentation
Creators: name: Xia, Jun
name: Xu, Jiaxing
name: Hu, Lei
name: Liu, Xiaoyan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Poly(L-malic acid) (PMA) is a natural polyester with many attractive properties for biomedical application. However, the cost of PMA production is high when glucose is used as the carbon source. To solve this problem, cane molasses as a low-cost feedstock was applied for the production of PMA. Six pretreatment methods were applied to cane molasses before fermentation. Pretreatment with combined tricalcium phosphate, potassium ferrocyanide and sulfuric acid (TPFSA) removed significant amounts of metal ions from cane molasses. The PMA concentration increased from 5.4 g/L (untreated molasses) to 36.9 g/L (TPFSA-pretreated molasses) after fermentation in shake flasks. A fed-batch fermentation strategy was then developed. In this method, TPFSA-pretreated cane molasses solution was continuously fed into the fermentor to maintain the total sugar concentration at 20 g/L. This technique generated approximately 95.4 g/L PMA with a productivity of 0.57 g L−1 h−1. The present study indicated that fed-batch fermentation using pretreated cane molasses is a feasible technique for producing high amounts of PMA.
Air quality mapping using GIS and economic evaluation of health impact for Mumbai City, India
Creators: name: Kumar, Awkash
name: Gupta, Indrani
name: Brandt, Jørgen
name: Kumar, Rakesh
name: Kumar Dikshit, Anil
name: Patil, Rashmi S.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Mumbai, a highly populated city in India, has been selected for air quality mapping and assessment of health impact using monitored air quality data. Air quality monitoring networks in Mumbai are operated by National Environment Engineering Research Institute (NEERI), Maharashtra Pollution Control Board (MPCB), and Brihanmumbai Municipal Corporation (BMC). A monitoring station represents air quality at a particular location, while we need spatial variation for air quality management. Here, air quality monitored data of NEERI and BMC were spatially interpolated using various inbuilt interpolation techniques of ArcGIS. Inverse distance weighting (IDW), Kriging (spherical and Gaussian), and spline techniques have been applied for spatial interpolation for this study. The interpolated results of air pollutants sulfur dioxide (SO2), nitrogen dioxide (NO2) and suspended particulate matter (SPM) were compared with air quality data of MPCB in the same region. Comparison of results showed good agreement for predicted values using IDW and Kriging with observed data. Subsequently, health impact assessment of a ward was carried out based on total population of the ward and air quality monitored data within the ward. Finally, health cost within a ward was estimated on the basis of exposed population. This study helps to estimate the valuation of health damage due to air pollution. Implications: Operating more air quality monitoring stations for measurement of air quality is highly resource intensive in terms of time and cost. The appropriate spatial interpolation techniques can be used to estimate concentration where air quality monitoring stations are not available. Further, health impact assessment for the population of the city and estimation of economic cost of health damage due to ambient air quality can help to make rational control strategies for environmental management. The total health cost for Mumbai city for the year 2012, with a population of 12.4 million, was estimated as USD8000 million.
Efficacy and safety of baricitinib in Japanese patients with active rheumatoid arthritis: A 52-week, randomized, single-blind, extension study
Creators: name: Tanaka, Yoshiya
name: Ishii, Taeko
name: Zhihong Cai
name: Schlichting, Douglas
name: Rooney, Terence
name: Macias, William
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Objectives: The objective of this study is to evaluate the efficacy and safety of long-term (64 weeks; 52-week extension of a 12-week study) baricitinib treatment in Japanese patients with active rheumatoid arthritis (RA) despite methotrexate therapy. Methods: Patients (N = 145) with active RA were randomized to placebo, 1mg, 2mg, 4mg, or 8mg baricitinib for the first 12 weeks. During the 52-week extension period, patients on 4mg or 8mg baricitinib remained on the same dose and all other patients were re-randomized to 4mg or 8mg baricitinib. Most patients on 8mg baricitinib were switched to 4mg by week 64 (protocol amendment); data analysis was based on the treatment group at the beginning of the extension period. Results: Increases in the American College of Rheumatology (ACR) response rates (ACR20, ACR50, and ACR70) observed during the first 12 weeks were maintained during the extension period, accompanied by improvements in ACR core components. At week 64, a large proportion of patients (>40%) had low disease activity. Most treatment-related adverse events were mild or moderate; herpes zoster was the most common reason (11/27 patients) for discontinuation. Conclusions: The efficacy and safety profile of baricitinib was maintained during long-term treatment of Japanese patients with RA and background methotrexate therapy. Clinicaltrials.gov NCT01469013; Funding: Eli Lilly and Incyte
A new bioactive diterpenoid from pestalotiopsis adusta, an endophytic fungus from clerodendrum canescens
Creators: name: Xu, Ming-Feng
name: Jia, Ou-Ya
name: Wang, Sheng-Jia
name: Zhu, Qin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Bioassay-guided fractionation of the culture extract of Pestalotiopsis adusta, an endophytic fungus isolated from the medicinal plant Clerodendrum canescens, led to the isolation of one new, (10S)-12,16-epoxy-17(15→16)-abeo-3,5,8,12,15-abietapentaen-2,7,11,14-tetraone (1), and four known diterpenoids, teuvincenone F (2), uncinatone (3), coleon U (4), coleon U-12-methyl ether (5). These structures were identified by using spectroscopic methods, including UV, MS, 1D and 2D NMR experiments. This is the first report of these compounds being isolated from a Pestalotiopsis species. The cytotoxic activities of the compounds were evaluated, and compounds 1 and 3 demonstrated cytotoxic activities against the HL-60 tumour cell line (IC50 ＜ 20 μM).
Effect of femoral head size and surgical approach on risk of revision for dislocation after total hip arthroplasty
Creators: name: Zijlstra, Wierd P
name: Hartog, Bas De
name: Steenbergen, Liza N Van
name: B Willem Scheurs
name: Nelissen, Rob G H H
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Background and purpose — Recurrent dislocation is the commonest cause of early revision of a total hip arthropasty (THA). We examined the effect of femoral head size and surgical approach on revision rate for dislocation, and for other reasons, after total hip arthroplasty (THA). Patients and methods — We analyzed data on 166,231 primary THAs and 3,754 subsequent revision THAs performed between 2007 and 2015, registered in the Dutch Arthroplasty Register (LROI). Revision rate for dislocation, and for all other causes, were calculated by competing-risk analysis at 6-year follow-up. Multivariable Cox proportional hazard regression ratios (HRs) were used for comparisons. Results — Posterolateral approach was associated with higher dislocation revision risk (HR =1) than straight lateral, anterolateral, and anterior approaches (HR =0.5–0.6). However, the risk of revision for all other reasons (especially stem loosening) was higher with anterior and anterolateral approaches (HR =1.2) and lowest with posterolateral approach (HR =1). For all approaches, 32-mm heads reduced the risk of revision for dislocation compared to 22- to 28-mm heads (HR =1 and 1.6, respectively), while the risk of revision for other causes remained unchanged. 36-mm heads increasingly reduced the risk of revision for dislocation but only with the posterolateral approach (HR =0.6), while the risk of revision for other reasons was unchanged. With the anterior approach, 36-mm heads increased the risk of revision for other reasons (HR =1.5). Interpretation — Compared to the posterolateral approach, direct anterior and anterolateral approaches reduce the risk of revision for dislocation, but at the cost of more stem revisions and other revisions. For all approaches, there is benefit in using 32-mm heads instead of 22- to 28-mm heads. For the posterolateral approach, 36-mm heads can safely further reduce the risk of revision for dislocation.
Supplementary Material for: Buffalo Leukemia Inhibitory Factor Induces Differentiation and Dome-Like Secondary Structures in COS-1 Cells
Creators: name: Kaur, G.
name: Ali, S.A.
name: Pachauri, S.
name: Malakar, D.
name: Kaushik, J.K.
name: Mohanty, A.K.
name: Kumar, S.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: This study aimed to understand the molecular characteristics of buffalo leukemia inhibitory factor (BuLIF) and the generation of a stably transfected COS-1_BuLIF cell line for its functional characterization. Cumulus cells, isolated from oocytes, were separated, and total cDNA was prepared. The BuLIF gene was ligated into the cloning vector pJET1.2/blunt and expression vector pAcGFP-N1 which was transfected into COS-1 cells and confirmed by qRT-PCR and Western blot. BuLIF was immunoprecipitated and evaluated through a MTT assay. qRT-PCR of STAT3 was performed. The multiple sequence alignment of BuLIF showed high similarity with sheep (98.77%) and cattle (96.62%) compared with other species. The BuLIF gene has an open reading frame of 609 nucleotides coding for 202 amino acids. BuLIF was integrated into the genome of COS-1 cells and resulted in the formation of dome-like secondary structures which are indicative of its functional role mediated through STAT3 proteins. In conclusion, this cell line is suitable for understanding LIF-mediated biological functions.
Development of a volatility and polarity separator (VAPS) for volatility- and polarity-resolved organic aerosol measurement
Creators: name: E. Martinez, Raul
name: J. Williams, Brent
name: Zhang, Yaping
name: Hagan, David
name: Walker, Michael
name: Kreisberg, Nathan M.
name: Hering, Susanne V.
name: Hohaus, Thorsten
name: Jayne, John T.
name: Worsnop, Douglas R.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Astronomical and Space Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Discrepancies between modeled and measured atmospheric organic aerosol (OA) have highlighted the need for in situ instrumentation to better characterize the sources, formation mechanisms, and atmospheric evolution of ambient OA. We have developed the Volatility and Polarity Separator (VAPS) for hourly measurements of volatility- and polarity-resolved OA detected using high-resolution time-of-flight mass spectrometry (HR-ToF-MS). Here, atmospheric OA is inertially impacted onto a collection cell, material is transferred onto a short transfer line located inside a gas chromatography (GC) oven, the oven is heated to provide a first-dimension separation of volatility, then thermally pulsed through a short polar GC column for a second-dimension polarity separation, and finally detected by HR-ToF-MS. This novel instrument increases the mass throughput of ambient OA in comparison to traditional GC due to shorter transfer paths and passivated coatings. Molecular separation resolution is partially sacrificed for this increased mass recovery, but the high-resolution mass spectral data recovers information such as chemical classes and even some individual compounds along with elemental composition to determine aerosol oxidation states. Different techniques for interpreting and representing VAPS data are considered and its applicability to positive matrix factorization (PMF) analysis is demonstrated. Copyright © 2016 American Association for Aerosol Research
Development of a Volatility and Polarity Separator (VAPS) for Volatility- and Polarity-Resolved Organic Aerosol Measurement
Creators: name: E. Martinez, Raul
name: J. Williams, Brent
name: Zhang, Yaping
name: Hagan, David
name: Walker, Michael
name: Kreisberg, Nathan M.
name: Hering, Susanne V.
name: Hohaus, Thorsten
name: Jayne, John T.
name: Worsnop, Douglas R.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Discrepancies between modeled and measured atmospheric organic aerosol (OA) have highlighted the need for in situ instrumentation to better characterize the sources, formation mechanisms, and atmospheric evolution of ambient OA. We have developed the Volatility and Polarity Separator (VAPS) for hourly measurements of volatility- and polarity-resolved OA detected using high-resolution time-of-flight mass spectrometry (HR-ToF-MS). Here, atmospheric OA is inertially impacted onto a collection cell, material is transferred onto a short transfer line located inside a gas chromatography (GC) oven,the oven is heated to provide a first dimension separation of volatility, then thermally pulsed through a short polar GC column for a second dimension polarity separation, and finally detected by HR-ToF-MS. This novel instrument increases the mass throughput of ambient OA in comparison to traditional GC due to shorter transfer paths and passivated coatings. Molecular separation resolution is partially sacrificed for this increased mass recovery, but the high-resolution mass spectral data recovers information such as chemical classes and even some individual compounds along with elemental composition to determine aerosol oxidation states. Different techniques for interpreting and representing VAPS data are considered and its applicability to positive matrix factorization (PMF) analysis is demonstrated.
A new epidioxy-tetracyclic triterpenoid from Poria cocos Wolf
Creators: name: Li, Shiping
name: Wang, Zhixin
name: Gu, Rui
name: Zhao, Yiwu
name: Huang, Wenzhe
name: Wang, Zhenzhong
name: Xiao, Wei
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Hematology

description: A new epidioxy-tetracyclic triterpenoid, 3-(2-hydroxyacetoxy)-5α, 8α-peroxydehydrotumulosic acid (10), along with nine known compounds were isolated from Poria cocos Wolf (Polyporaceae). Their structures were determined by extensive spectroscopic analyses and comparison with literature data. The cytotoxicity of these compounds against human cancer cell lines MNK-45 was evaluated by MTT method.
Supplementary Material for: Protection against Legionnaire's Disease: Recombinant Flagellin A of Legionella pneumophila Can Induce Protective Immunity against Bacteremia in a BALB/c Murine Model
Creators: name: Mohabati Mobarez, A.
name: Ahmadrajabi, R.
name: Khoramabadi, N.
name: Salmanian, A.-H.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: To investigate the immunoprotective effects of the recombinant type A flagellin (FLA), the flaA gene of Legionella pneumophila serogroup 1 strain Paris was cloned into pET28a(+). Recombinant FLA (rFLA) was overexpressed in E. coli BL21 (DE3) and purified by Ni2+ exchange chromatography. Female BALB/c aged 6-8 weeks were immunized with 20 μg of rFLA. Nonimmunized mice along with mice inoculated with a sublethal dose of live L. pneumophila intravenously were considered as negative and positive controls, respectively. A significant serum antibody response was observed in female BALB/c mice immunized with rFLA. Production of IFN-γ and IL-12, and TNF-α in the serum and the splenocyte cultures, and antigen-specific splenocyte proliferation suggested a strong innate and adaptive cell-mediated immunity response in rFLA-immunized mice. Intravenous lethal challenge with L. pneumophila serogroup 1 (strain Paris) showed that 60% of mice immunized with rFLA survived in a 10-day follow-up survey. These results show that rFLA from L. pneumophila can elicit strong innate and adaptive immune responses and suggest the possibility of a long-term immunity against lethal challenge with L. pneumophila.
Combined evaluation of risk factors predicting poor ovarian responders in Chinese patients undergoing in vitro fertilization
Creators: name: Huang, Lu
name: Wang, Shuyu
name: Ma, Yanmin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: This study aimed to explore the parameters associated with poor ovarian response (POR) to develop an early warning score model (EWSM) for detecting POR in Chinese women undergoing in vitro fertilization, in order to improve the outcomes. Between 2005 and 2011, we recruited 736 patients with POR after IVF and 736 individuals with normal ovarian response after IVF as controls. Clinical parameters were determined to evaluate the ovarian reserve. We then compared the clinical parameters between the POR and control groups, and performed a multivariate analysis to determine the independent factors associated with ovarian response. Receiver-operator characteristic (ROC) was used to analyze the predicted values of individual and combined risk factors. The predicted values were further tested in another cohort of 957 patients. Age, basal follicle-stimulating hormone (bFSH), antral follicle count (AFC), and FSH/luteinizing hormone (LH) ratio were identified as independent factors associated with ovarian response. The EWSM was established using a combination of these parameters. The sensitivity and specificity of the EWSM were 74.6% and 93.6%, respectively. In conclusion, combination of individual risk factors could predict POR with high specificity. The EWSM may help in the evaluation of IVF treatment at an early stage.
Explanation of Existing Data
Creators: name: Mumby, Patricia
name: Schneider, Kristin
name: Kumar, Esha Rani
Publisher: name: OSF Registries
Year: 2021

description: The proposed study is a secondary analysis of pre-collected data of a study examining the utility of the Stanford Integrated Psychosocial Assessment for Transplantation in adult stem cell and bone marrow transplant recipients at Loyola University Medical Center (LUMC) in Maywood, IL. The study was approved by the Institutional Review Board of LUMC in 2012 (IRB: 204953120612).

The current researcher has access to the data, however data analyses have not occurred. Data will be analyzed upon the registration with Open Science.
Volumetric and compressibility studies for (L-arginine + D-maltose monohydrate + water) system in the temperature range of (298.15 to 308.15) K
Creators: name: Kumar, Ashwani
name: Rani, Ruby
name: Gupta, Anjana
name: Saini, Balwinder
name: K Bamezai, Rajinder
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Virology

description: The density and speed of sound of L-arginine (0.025–0.2 mol kg−1) in aqueous + D-maltose (0–6 mass% of maltose in water) were obtained at temperatures of (298.15, 303.15 and 308.15) K. The apparent molar volume, limiting apparent molar volume, transfer volume, as well as apparent molar compressibility, limiting apparent molar compressibility, transfer compressibility, pair and triple interaction coefficients, partial molar expansibilities, coefficient of thermal expansion and also the hydration number, were calculated using the experimental density and speed of sound values. The results have been discussed in terms of solute–solute and solute–solvent interactions in these systems. Solute–solvent (hydrophilic–ionic group and hydrophilic–hydrophilic group) interactions were found to be dominating over solute–solute (hydrophobic–hydrophilic group) interactions in the solution, which increases with increase in maltose concentration.
Supplementary Material for: Ultraviolet A1 Phototherapy in the Treatment of Early Mycosis Fungoides
Creators: name: Adışen, E.
name: Tektaş, V.
name: Erduran, F.
name: Ö., Erdem
name: Gürer, M.A.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: Phototherapy has been the mainstay of therapies for early mycosis fungoides (MF). The beneficial role of ultraviolet (UV) light on MF is suggested by the observation that lesions occur on non-sun-exposed areas. Therapeutic light sources that are available today are broadband UVB, psoralen and UVA, narrowband UVB, and long-wave UV (UVA1). Current literature provides increasing evidence on the use of UVA1 to treat MF. Aim: To investigate the treatment responses of early MF patients treated with fixed 30 J/cm2 doses of UVA1 phototherapy. Material and Methods: Nineteen patients with early MF, stage IA-IIA of the TNM staging system, received fixed 30 J/cm2 doses of UVA1, given 5 times weekly over 5 weeks. Therapeutic effectiveness was assessed by clinical examination and was confirmed by histological evaluation. Results: Of the 19 patients, complete responses were achieved in 12 (63%) and partial responses were achieved in 7 (37%) patients after UVA1 radiation exposures. During the study, UVA1 therapy was well tolerated. During the follow-up, 7 (58%) of the 12 patients with complete response relapsed within 3 months of the UVA1 therapy. Conclusion: The current study provides clinical and histological evidence for the effectiveness of UVA1 (30 J/cm2 5 times a week for 5 weeks) as a skin-directed therapy in the treatment of early MF; however, such a treatment failed to maintain a long and sustained response. Thus, studies to identify the optimal dosing protocol regarding the therapeutic efficacy, the factors affecting relapse time/rate, and the necessity of maintenance treatment are needed.
Additional methodological details, figures and tables from Gene flow in the Antarctic bivalve Aequiyoldia eightsii (Jay, 1839) suggests a role for the Antarctic Peninsula Coastal Current in larval dispersal
Creators: name: Muñoz-Ramírez, Carlos
name: Barnes, David K. A.
name: Cardenas, Leyla
name: Meredith, Michael P.
name: Morley, Simon A.
name: Roman-Gonzalez, Alejandro
name: Sands, Chester J.
name: Scourse, James
name: Brante, Antonio
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60302 Biogeography and Phylogeography

description: Additional methodological details, figures and tables
Plastic film mulching on soil water and maize (Zea mays L.) yield in a ridge cultivation system on Loess Plateau of China
Creators: name: Jiang, Rui
name: Li, Xiao
name: Zhou, Minghua
name: Jie Li, Hui
name: Zhao, Ying
name: Yi, Jun
name: Le Cui, Le
name: Li, Ming
name: Guo Zhang, Jian
name: Qu, Dong
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Plastic film mulching has commonly been used for adaptation to water scarcity and for increasing agricultural productivity on the semiarid Loess Plateau of China. However, the effect of plastic film mulching on cropland soil water and thermal regimes on the semiarid Loess Plateau of China is not well understood. This study simultaneously monitored the dynamics of the soil water content and the soil temperature with high resolution in a ridge cultivation system with plastic film mulching (RS) and a flat cultivation system without plastic film mulching (FS) during the maize (Zea mays L.)-growing season. We found that, in general, the soil temperature and soil water content were significantly different among the ridge under RS (RS-ridge), the furrow under RS (RS-furrow) and FS throughout the maize-growing season (P < 0.05). Plastic film mulching increased the near-surface soil temperature by approximately 1°C throughout the study period. RS significantly increased the soil water content during the dry period (May to June), especially within the middle soil layer (30–60 cm), compared to FS. The lowest monthly average soil water content was found at a depth of 30–60 cm layer in FS during the dry period (May and June). The water depletion was found within deeper (100–160 cm) soil layers in May but the water storage in the same layer of FS in June increased although it was the dry period, which differed from RS. The RS practices showed a longer period of water supply from the deeper soil layer (100–160 cm) in May and June for meeting maize water demands during the early growing stage rather than in only May for FS. During June (dry period), the water storage at a depth of 0–60 cm was greater in RS than in FS, and the reverse was true at a depth of 60–160 cm. The results indicate that the dry soil layer at a depth of 30–60 cm formed during June in FS likely reduced water movement from deeper layers to the topsoil layer, and hence constrained the availability of surface soil water for meeting maize water requirements during the early growing stage (dry period). Our study suggests that RS tends to significantly increase surface soil water availability by restraining the formation of a dry soil layer during the early maize-growth stage primarily under dry conditions, and thus enhances maize productivity in the semiarid Loess Plateau of China.
Plastic film mulching on soil water and maize (Zea mays L.) yield in a ridge cultivation system on Loess Plateau of China
Creators: name: Jiang, Rui
name: Li, Xiao
name: Zhou, Minghua
name: Jie Li, Hui
name: Zhao, Ying
name: Yi, Jun
name: Le Cui, Le
name: Li, Ming
name: Guo Zhang, Jian
name: Qu, Dong
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Plastic film mulching has commonly been used for adaptation to water scarcity and for increasing agricultural productivity on the semiarid Loess Plateau of China. However, the effect of plastic film mulching on cropland soil water and thermal regimes on the semiarid Loess Plateau of China is not well understood. This study simultaneously monitored the dynamics of the soil water content and the soil temperature with high resolution in a ridge cultivation system with plastic film mulching (RS) and a flat cultivation system without plastic film mulching (FS) during the maize (Zea mays L.)-growing season. We found that, in general, the soil temperature and soil water content were significantly different among the ridge under RS (RS-ridge), the furrow under RS (RS-furrow) and FS throughout the maize-growing season (P < 0.05). Plastic film mulching increased the near-surface soil temperature by approximately 1°C throughout the study period. RS significantly increased the soil water content during the dry period (May to June), especially within the middle soil layer (30–60 cm), compared to FS. The lowest monthly average soil water content was found at a depth of 30–60 cm layer in FS during the dry period (May and June). The water depletion was found within deeper (100–160 cm) soil layers in May but the water storage in the same layer of FS in June increased although it was the dry period, which differed from RS. The RS practices showed a longer period of water supply from the deeper soil layer (100–160 cm) in May and June for meeting maize water demands during the early growing stage rather than in only May for FS. During June (dry period), the water storage at a depth of 0–60 cm was greater in RS than in FS, and the reverse was true at a depth of 60–160 cm. The results indicate that the dry soil layer at a depth of 30–60 cm formed during June in FS likely reduced water movement from deeper layers to the topsoil layer, and hence constrained the availability of surface soil water for meeting maize water requirements during the early growing stage (dry period). Our study suggests that RS tends to significantly increase surface soil water availability by restraining the formation of a dry soil layer during the early maize-growth stage primarily under dry conditions, and thus enhances maize productivity in the semiarid Loess Plateau of China.
Trajectory Data Mining and Trip Travel Time Prediction on Specific Roads
Creators: name: Amin, Muhammad Awais
name: Chughtai, Jawad-Ur-Rehman
name: Ahmad, Waqar
name: Bangyal, Waqas Haider
name: Haq, Irfan Ul
Publisher: name: arXiv
Year: 2024
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Predicting a trip's travel time is essential for route planning and navigation applications. The majority of research is based on international data that does not apply to Pakistan's road conditions. We designed a complete pipeline for mining trajectories from sensors data. On this data, we employed state-of-the-art approaches, including a shallow artificial neural network, a deep multi-layered perceptron, and a long-short-term memory, to explore the issue of travel time prediction on frequent routes. The experimental results demonstrate an average prediction error ranging from 30 seconds to 1.2 minutes on trips lasting 10 minutes to 60 minutes on six most frequent routes in regions of Islamabad, Pakistan.
description: N/A
New zircon U-Pb ages of the pre-Sturtian rift successions from the western Yangtze Block, South China and their geological significance
Creators: name: Jiang, Zhuo-Fei
name: Cui, Xiao-Zhuang
name: Jiang, Xin-Sheng
name: Wang, Jian
name: Zhuo, Jie-Wen
name: Xiong, Guo-Qing
name: Lu, Jun-Ze
name: Wu, Hao
name: Wei, Ya-Nan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: The Neoproterozoic Kaijianqiao Formation is one of the most important pre-Sturtian rift successions in South China and there has long been a lack of reliable geochronological constraints for its minimum depositional age. In this study, new zircon U-Pb ages of volcaniclastic rocks from the topmost Kaijianqiao Formation are presented. The youngest SHRIMP and LA-ICP-MS zircon 206Pb/238U weighted mean ages of the tuff sample are 715.0 ± 9.8 and 718.8 ± 9.4 Ma, respectively. The youngest LA-ICP-MS zircon 206Pb/238U weighted mean age of the tuffaceous siltstone sample is 720.8 ± 7.4 Ma and represents the maximum depositional age of the topmost Kaijianqiao Formation. The results show that the minimum depositional age of the Kaijianqiao Formation in the western Yangtze Block should be ca. 715 Ma, consistent with other pre-Sturtian rift successions in South China, such as the Banxi Group, Chengjiang, and Liantuo formations. Together with the published zircon U-Pb ages, it is demonstrated that the Sturtian glaciation in South China (Jiangkou glaciation) most likely initiated around 715 Ma. In other Rodinia blocks, like Laurentia and Arabia, the Sturtian glaciation probably started between 712 and 717 Ma, thus our new results further support that the Sturtian glaciation was a rapid and globally synchronous event. Other 206Pb/238U zircon ages display five distinct peaks at ca. 751, 780, 799, 819, and 848 Ma, which corresponded to the tectonic-magmatic events related to the break-up of Rodinia.
A critical review of the Kibyra Fault (Burdur-Fethiye Shear Zone, SW Turkey)
Creators: name: İrem Elitez
name: Yaltırak, Cenk
name: Akın Kürçer
name: Özdemir, Ersin
name: Çağıl Uygun Güldoğan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The Kibyra Fault is considered as the most significant evidence about the existence of the NE–SW-striking left-lateral Burdur-Fethiye Fault Zone in the south-western Anatolia in previous studies. However, recent studies show that there is a shear regime, named the Burdur-Fethiye Shear Zone, dominated by normal and left-lateral oblique normal faults in this region. A large number of ancient cities lie on this zone and many of them have been damaged by ancient earthquakes. One of these ancient cities is the ancient city of Kibyra. Most of previous studies suggest the Kibyra Fault depending on the damage in the city. However, the closest fault is located on the western side of the city and the earthquake damage was most likely caused by ground shaking. In this study, the existence of the supposed Kibyra Fault is discussed by integrating field studies, geological maps, trench data, digital elevation model and geomorphological analysis. In conclusion, it is understood that there is no evidence directly indicating a 35-km-long left-lateral fault in this region. The aim of this study is to examine the existence of the Kibyra Fault, take a different approach to the active fault studies and emphasise the importance of active faults for socio-economic conditions.
Exploring the role of classroom-based learning in professional identity formation of family practice residents using the experiences, trajectories, and reifications framework
Creators: name: Chen, Luke Y. C.
name: Hubinette, Maria M.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Background: Classroom-based learning such as academic half day has undervalued social aspects. We sought to explore its role in the professional identity development of family medicine residents. Methods: In this case study, residents and faculty from four training sites in the University of British Columbia Department of Family Practice were interviewed. The “experiences, trajectories, and reifications (ETR) framework” was used as a sensitizing tool for modified inductive (thematic) analysis of the transcripts. Results: Classroom-based learning provided a different context for residents’ interpretation of their clinical experiences, characterized as a “home base” for rotating urban residents, and a connection to a larger academic community for residents in rural training sites. Both these aspects were important in creating a positive trajectory of professional identity formation. Teaching directed at the learning needs of family physicians, and participation of family practice faculty as teachers and role models was a precipitation of a curriculum “centered in family medicine.” Interactions between family medicine residents and faculty in the classroom facilitated the necessary engagements to reify a shared understanding of the discipline of family practice. Conclusions: Classroom-based learning has substantial impact on professional identity formation at an individual and collective level.
Long non-coding RNA ANRIL regulates inflammatory responses as a novel component of NF-κB pathway
Creators: name: Zhou, Xiao
name: Han, Xiaorui
name: Wittfeldt, Ann
name: Sun, Jingzhi
name: Liu, Chujun
name: Wang, Xiaoxia
name: Gan, Li-Ming
name: Cao, Huiqing
name: Liang, Zicai
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Computational Biology

description: Antisense Noncoding RNA in the INK4 Locus (ANRIL) is the prime candidate gene at Chr9p21, the well-defined genetic risk locus associated with multiple human diseases including coronary artery disease (CAD), while little is known regarding its role in the pathological processes. Endothelial dysfunction triggers atherosclerotic processes that are causatively linked to CAD. To evaluate the function of ANRIL in human endothelial cells (ECs), we examined ANRIL expression under pathological stimuli and found ANRIL was markedly induced by pro-inflammatory factors. Loss-of-function and chromatin immunoprecipitation approaches revealed that NF-κB mediates TNF-α induced ANRIL expression. RNA sequencing revealed that ANRIL silencing dysregulated expression of inflammatory genes including IL6 and IL8 under TNF-α treatment. We explored the regulatory mechanism of ANRIL on IL6/8 and found that Yin Yang 1 (YY1), an ANRIL binding transcriptional factor revealed by RNA immunoprecipitation, was required for IL6/8 expression under TNF-α treatment. YY1 was enriched at promoter loci of IL6/8 and ANRIL silencing impaired the enrichment, indicating a cooperation between ANRIL and YY1 in the regulation of inflammatory genes. For the first time, we establish the connection between ANRIL and NF-κB pathway and show that ANRIL regulates inflammatory responses through binding with YY1. The newly identified TNF-α-NF-κB-ANRIL/YY1-IL6/8 pathway enhances understanding of the etiology of CAD and provides potential therapeutic target for treatment of CAD.
Essential oil composition and antibacterial activity of Lindera nacusua (D. Don) Merr.
Creators: name: Wei, Guoqing
name: Kong, Lin
name: Zhang, Jiasui
name: Ma, Chaoying
name: Wu, Xiaoqing
name: Li, Xueru
name: Jiang, Hezhong
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: This study represents the first report on the chemical composition and biological activity of the essential oils from the leaves of Lindera nacusua (D. Don) Merr. Twenty-two compounds were identified and quantified, and the major components of the oil were Caryophyllene oxide (8.79%), Hexahydrofarnesyl acetone (6.83%), β-Selinene (5.02%), Neophytadiene (4.53%), Palmitic acid (4.42%), Phytol (4.36%), α-Copaene (3.89%), 4a,5,8,8a-β-Tetrahydro-2,4,5-trimethyl-1,4-naphthalindione (3.83%), α-Cadinol (3.17%), Bulnesol (2.65%) and 1,4-Dimethyl-7-(1-methylethyl) azulene (2.38%). The in vitro antibacterial activities of the essential oils were evaluated by the disc diffusion method. The inhibition zones against Staphylococcus aureus and Candida albicans were 23.7 and 23 mm. So the essential oil of L. nacusua showed potent antibacterial activity and potential high selectivity against S. aureus and C. albicans.