cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Feedback from Winds and Supernovae in Massive Stellar Clusters. I: Hydrodynamics
Creators: name: Rogers, H.
name: Pittard, J. M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We use 3D hydrodynamical models to investigate the effects of massive star feedback from winds and supernovae on inhomogeneous molecular material left over from the formation of a massive stellar cluster. We simulate the interaction of the mechanical energy input from a cluster with 3 O-stars into a giant molecular cloud (GMC) clump containing 3240 solar masses of molecular material within a 4 pc radius. The cluster wind blows out of the molecular clump along low-density channels, into which denser clump material is entrained. We find that the densest molecular regions are surprisingly resistant to ablation by the cluster wind, in part due to shielding by other dense regions closer to the cluster. Nonetheless, molecular material is gradually removed by the cluster wind during which mass-loading factors in excess of several 100 are obtained. Because the clump is very porous, 60-75 per cent of the injected wind energy escapes the simulation domain, with the difference being radiated. After 4.4 Myr, the massive stars in our simulation begin to explode as supernovae. The highly structured environment into which the SN energy is released allows even weaker coupling to the remaining dense material and practically all of the SN energy reaches the wider environment. The molecular material is almost completely dispersed and destroyed after 6 Myr. The escape fraction of ionizing radiation is estimated to be about 50 per cent during the first 4 Myr of the cluster's life. A similar model with a larger and more massive GMC clump reveals the same general picture, though more time is needed for it to be destroyed.
description: 16 pages, 18 figures, accepted for publication in MNRAS
Global bifurcations to subcritical magnetorotational dynamo action in Keplerian shear flow
Creators: name: Riols, A.
name: Rincon, F.
name: Cossu, C.
name: Lesur, G.
name: Longaretti, P. -Y.
name: Ogilvie, G. I.
name: Herault, J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Chaotic Dynamics (nlin.CD)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Magnetorotational dynamo action in Keplerian shear flow is a three-dimensional, nonlinear magnetohydrodynamic process whose study is relevant to the understanding of accretion and magnetic field generation in astrophysics. Transition to this form of dynamo is subcritical and shares many characteristics of transition to turbulence in non-rotating hydrodynamic shear flows. This suggests that these different fluid systems become active through similar generic bifurcation mechanisms, which in both cases have eluded detailed understanding so far. In this paper, we investigate numerically the bifurcation mechanisms at work in the incompressible Keplerian magnetorotational dynamo problem in the shearing box framework. Using numerical techniques imported from dynamical systems research, we show that the onset of chaotic dynamo action at magnetic Prandtl numbers larger than unity is primarily associated with global homoclinic and heteroclinic bifurcations of nonlinear magnetorotational dynamo cycles. These global bifurcations are supplemented by local bifurcations of cycles marking the beginning of period-doubling cascades. This suggests that nonlinear magnetorotational dynamo cycles provide the pathway to turbulent injection of both kinetic and magnetic energy in incompressible magnetohydrodynamic Keplerian shear flow in the absence of an externally imposed magnetic field. Studying the nonlinear physics and bifurcations of these cycles in different regimes and configurations may subsequently help to better understand the conditions of excitation of magnetohydrodynamic turbulence and instability-driven dynamos in various astrophysical systems and laboratory experiments. The detailed characterization of global bifurcations provided for this three-dimensional subcritical fluid dynamics problem may also prove useful for the problem of transition to turbulence in hydrodynamic shear flows.
description: 43 pages, 17 figures, accepted for publication in J. Fluid Mech
title: Resurgence of Cocaine-Seeking in Rats Following Long Access and Punishment
Creators: name: Nall, Rusty W.
Publisher: name: Utah State University
Year: 2019

description: Strategies that provide access to alternative non-drug rewards are among the most effective at reducing substance use in individuals with substance use disorders, but relapse often occurs when alternative rewards are removed. Relapse induced by the loss of alternative rewards is called resurgence, and represents a challenge to otherwise effective strategies for reducing drug use. An animal model has been useful for studying resurgence, but the extant model has two limitations. First, humans usually refer to the negative consequences of drug use as the reason they stop taking drugs, but the extant model uses drug unavailability to reduce drug seeking. Second, individuals with substance use disorders display behaviors that can be summarized as uncontrolled drug seeking, but the extant model does not simulate uncontrolled drug seeking. Chapter 2 addressed the first concern by studying resurgence of previously-punished cocaine seeking. Chapter 3 addressed the second concern by using procedures shown to simulate uncontrolled drug seeking in rats to study resurgence of previously-punished cocaine seeking. Chapter 2 showed that resurgence of cocaine seeking can occur following suppression by punishment, and Chapter 3 showed that resurgence may be unaffected following procedures shown to increase relapse in other models. The models developed herein should contribute to future research into resurgence by better simulating the conditions under which individuals with substance use disorders experience relapse.
Maximizing the capture velocity of molecular magneto-optical traps with Bayesian optimization
Creators: name: Xu, Supeng
name: Kaebert, Paul
name: Stepanova, Mariia
name: Poll, Timo
name: Siercke, Mirco
name: Ospelkaus, Silke
Publisher: name: Bristol, Bad Honnef : IOP Publishing Ltd., Deutsche Physikalische Gesellschaft
Year: 2021
Subjects: subject: Atomic and molecular physics
subject: quantum gases
subject: magneto-optical trap
subject: laser cooling
subject: cold molecules
subject: Bayesian optimization
subject: Ultrakalte Gase
subject: Atom- und Molekülphysik
subject: Dewey Decimal Classification::500 | Naturwissenschaften
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: Magneto-optical trapping (MOT) is a key technique on the route towards ultracold molecular ensembles. However, the realization and optimization of magneto-optical traps with their wide parameter space is particularly difficult. Here, we present a very general method for the optimization of molecular magneto-optical trap operation by means of Bayesian optimization. As an example for a possible application, we consider the optimization of a calcium fluoride MOT for maximum capture velocity. We find that both the X2Σ+ to A2Π1/2 and the X2Σ+ to B2Σ+ transition to allow for capture velocities with 24 m s−1 and 23 m s−1 respectively at a total laser power of 200 mW. In our simulation, the optimized capture velocity depends logarithmically on the beam power within the simulated power range of 25 to 400 mW. Applied to heavy molecules such as BaH, BaF, YbF and YbOH with their low capture velocity MOTs it might offer a route to far more robust MOT.
title: Dementia Caregiver Coping Strategies and Caregiver-Care Recipient Relationship Closeness: Associations with Care-Recipient Outcomes
Creators: name: BehrensBerg, Stephanie
Publisher: name: Utah State University
Year: 2019

description: This project used data from the Dementia Progression Study, a longitudinal, population-based study based out of Cache County, Utah. Statistical models were used to examine the association between caregiver factors, the care environment, and cognitive outcomes in persons with dementia. Mediational analyses were also used to examine if the care environment, inferred for nutritional status, engagement in physical and cognitively stimulating activities, mediated the relationship between the closeness/caregiver coping strategies and cognition in persons with dementia. Results showed that closer caregiver-care recipient relationships were associated with better nutritional status and more engagement in number of cognitively stimulating activities as well as better cognitive scores (category verbal fluency, short-term auditory memory, auditory working memory, and immediate verbal memory). Coping strategies were not significantly associated with aspects of the care environment but Blames Self coping strategy was associated with better performance on a measure of verbal fluency, whereas Blames Others coping was associated with worse performance in confrontation naming. The care environment was not a mediator between caregiver factors and cognition, though if allowing for a broader criterion of statistical significance (.10), nutritional status mediated the relationship between closeness and the neuropsychological outcome, semantic fluency. The results of this project identify targets of intervention (caregiver-care recipient closeness and caregiver coping strategies) that may positively impact persons with dementia in possibly improving care-recipient outcomes.
Tibet- Interior of Tibetan Temple and Mode of Worshipping
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2020
Subjects: Tibetans
Buddhist temples

description: Raphael Tuck & Sons postcard featuring whorshippers circumbulating th einner closure of a temple, in its Oilette Series on Tibet. Painting is adapted from "Tibet" by A. Henry Savage Landor.
Multi-sensor remote sensing analysis of coal fire induced land subsidence in Jharia Coalfields, Jharkhand, India
Creators: name: Karanam, Vamshi
name: Motagh, Mahdi
name: Garg, Shagun
name: Jain, Kamal
Publisher: name: Amsterdam [u.a.] : Elsevier Science
Year: 2021
Subjects: subject: Coal fires
subject: Coal mining
subject: Land subsidence
subject: Land surface temperature
subject: Persistent scatterer interferometry
subject: Temperature anomaly
subject: coal mining
subject: fire
subject: interferometry
subject: land surface
subject: remote sensing
subject: sensor
subject: subsidence
subject: surface temperature
subject: temperature anomaly
subject: Bihar
subject: India
subject: Jharia Coalfield
subject: Jharkhand
subject: Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaften

description: The subsidence in coal mines induced by surface and subsurface fires leading to roof collapse, infrastructure loss, and loss of lives is a prominent concern. In the study, satellite imagery from thermal and microwave remote sensing data is used to deduce the effect of coal fires on subsidence in the Jharia Coalfields, India. The Thermal Infrared data acquired from the Landsat-8 (band 10) is used to derive the temperature anomaly maps. Persistent Scatterer Interferometry analysis was performed on sixty Sentinel-1, C-band images, the results are corrected for atmospheric error using Generic Atmospheric Correction Online Service for InSAR (GACOS) atmospheric modelling data and decomposed into vertical displacement values to quantify subsidence. A zone-wise analysis of the hazard patterns in the coalfields was carried out. Coal fire maps, subsidence velocity maps, and land cover maps were integrated to investigate the impact of the hazards on the mines and their surroundings. Maximum subsidence of approximately 20 cm/yr. and temperature anomaly of up to 25 °C has been observed. The findings exhibit a strong positive correlation between the subsidence velocity and temperature anomaly in the study area. Kusunda, Keshalpur, and Bararee collieries are identified as the most critically affected zones. The subsidence phenomenon in some collieries is extending towards the settlements and transportation networks and needs urgent intervention. © 2021 The Authors
High unawareness of chronic kidney disease in Germany
Creators: name: Stolpe, Susanne
name: Kowall, Bernd
name: Scholz, Christian
name: Stang, Andreas
name: Blume, Cornelia
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: Chronic kidney disease
subject: CKD unawareness
subject: Gender differences
subject: disease
subject: disease prevalence
subject: gender disparity
subject: health risk
subject: regression analysis
subject: risk factor
subject: adult
subject: aged
subject: awareness
subject: body mass
subject: chronic kidney failure
subject: cohort analysis
subject: comorbidity
subject: diabetes mellitus
subject: disease classification
subject: groups by age
subject: human
subject: hypertension
subject: major clinical study
subject: male
subject: middle aged
subject: prevalence
subject: sex difference
subject: Diabetes Mellitus
subject: Female
subject: Germany
subject: Humans
subject: Kidney Failure, Chronic
subject: Renal Insufficiency, Chronic
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau
subject: Dewey Decimal Classification::600 | Technik::690 | Hausbau, Bauhandwerk

description: Chronic kidney disease (CKD) is associated with an increased risk for cardiovascular events, hospitalizations, end stage renal disease and mortality. Main risk factors for CKD are diabetes, hypertension, and older age. Although CKD prevalence is about 10%, awareness for CKD is generally low in patients and physicians, hindering early diagnosis and treatment. We analyzed baseline data of 3305 participants with CKD Stages 1–4 from German cohorts and registries collected in 2010. Prevalence of CKD unawareness and prevalence ratios (PR) (each with 95%-confidence intervals) were estimated in categories of age, sex, CKD stages, BMI, hypertension, diabetes and other relevant comorbidities. We used a log-binomial regression model to estimate the PR for CKD unawareness for females compared to males adjusting for CKD stage and CKD risk factors. CKD unawareness was high, reaching 71% (68–73%) in CKD 3a, 49% (45–54%) in CKD 3b and still 30% (24–36%) in CKD4. Prevalence of hypertension, diabetes or cardiovascular comorbidities was not associated with lower CKD unawareness. Independent of CKD stage and other risk factors unawareness was higher in female patients (PR = 1.06 (1.01; 1.10)). Even in patients with CKD related comorbidities, CKD unawareness was high. Female sex was strongly associated with CKD unawareness. Guideline oriented treatment of patients at higher risk for CKD could increase CKD awareness. Patient–physician communication about CKD might be amendable. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Adreus Gray 1867
Creators: name: Morrow, Christine
name: Cárdenas, Paco
name: Boury-Esnault, Nicole
name: Picton, Bernard
name: Mccormack, Grace
name: Soest, Rob Van
name: Collins, Allen
name: Redmond, Niamh
name: Maggs, Christine
name: Sigwart, Julia
name: Allcock, Louise A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Demospongiae
Tethyida
Hemiasterellidae
Adreus

description: GENUS ADREUS GRAY, 1867
Emended diagnosis: Arborescent growth form; choanosomal skeleton with strongly compressed axis composed of long smooth tylostyles in bundles running longitudinally through branches; poorly developed extra-axial skeleton composed of sparse plumose brushes of smaller smooth styles ascending to periphery; euasters with curved or sinuous, smooth or spined, strongylote or tylote rays often branched, mainly confined to the ectosomal region, absent in some species.
Type species: Adreus fascicularis (Bowerbank, 1866).
Included species: Van Soest et al. (2018) listed three valid species: Adreus fascicularis (Bowerbank, 1866); Adreus micraster (Burton, 1956); and Adreus stylifer (Arndt, 1927). On the basis of molecular evidence presented in the Supporting Information (Fig. S5), we formally propose the transfer of Raspailia (Parasyringella) australiensis Ridley, 1884 and Ceratopsion axiferum (Hentschel, 1912) to Adreus (see below, Adreus axiferum).
Remarks: In addition to arborescent growth forms, we have also collected an undescribed encrusting Adreus (BELUM Mc4982); this species is represented in our 18S rRNA gene tree (Supporting Information, Fig. S2).
Erpenbeck et al. (2007), in an analysis of the systematics of Raspailiidae using partial 28S rRNA sequences, showed that Raspailia (Parasyringella) australiensis and Ceratopsion axiferum did not cluster with the main raspailiid group. In an attempt to resolve the taxonomic affinities of some of their ‘raspailiid’ taxa that failed to group with the main raspailiid clade, we combined many of their sequences with our own (Supporting Information, Fig. S5). Our analysis indicates that, rather than being raspailiids that have lost their acanthostyles, Raspailia (Parasyringella) australiensis and Ceratopsion axiferum are better interpreted as Adreus that have secondarily lost their asters. For these species, we propose the new combinations Adreus australiensis and Adreus axiferum.
description: Published as part of Morrow, Christine, Cárdenas, Paco, Boury-Esnault, Nicole, Picton, Bernard, Mccormack, Grace, Soest, Rob Van, Collins, Allen, Redmond, Niamh, Maggs, Christine, Sigwart, Julia & Allcock, Louise A., 2019, Integrating morphological and molecular taxonomy with the revised concept of Stelligeridae (Porifera: Demospongiae), pp. 31-81 in Zoological Journal of the Linnean Society 187 on pages 75-76
Ultrasmall divergence of laser-driven ion beams from nanometer thick foils
Creators: name: Bin, J. H.
name: Ma, W. J.
name: Allinger, K.
name: Wang, H. Y.
name: Kiefer, D.
name: Reinhardt, S.
name: Hilz, P.
name: Khrennikov, K.
name: Karsch, S.
name: Yan, X. Q.
name: Krausz, F.
name: Tajima, T.
name: Habs, D.
name: Schreiber, J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: We report on experimental studies of divergence of proton beams from nanometer thick diamond-like carbon (DLC) foils irradiated by an intense laser with high contrast. Proton beams with extremely small divergence (half angle) of 2 degree are observed in addition with a remarkably well-collimated feature over the whole energy range, showing one order of magnitude reduction of the divergence angle in comparison to the results from micrometer thick targets. We demonstrate that this reduction arises from a steep longitudinal electron density gradient and an exponentially decaying transverse profile at the rear side of the ultrathin foils. Agreements are found both in an analytical model and in particle-in-cell simulations. Those novel features make nm foils an attractive alternative for high flux experiments relevant for fundamental research in nuclear and warm dense matter physics.
description: 11 pages, 5 figures
Shock jump relations for a dusty gas atmosphere
Creators: name: Anand, R. K.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: This paper presents generalized forms of jump relations for one dimensional shock waves propagating in a dusty gas. The dusty gas is assumed to be a mixture of a perfect gas and spherically small solid particles, in which solid particle are continuously distributed. The generalized jump relations reduce to the Rankine-Hugoniot conditions for shocks in an idea gas when the mass fraction (concentration) of solid particles in the mixture becomes zero. The jump relations for pressure, density, temperature, particle velocity, and change-in-entropy across the shock front are derived in terms of upstream Mach number. Finally, the useful forms of the shock jump relations for weak and strong shocks, respectively, are obtained in terms of the initial volume fraction of the solid particles. The computations have been performed for various values of mass concentration of the solid particles and for the ratio of density of solid particles to the constant initial density of gas. Tables and graphs of numerical results are presented and discussed.
description: 22 Figures and 26 pages
Enzymatische Minimierung von Chlorogensäuren in Getränken
Creators: name: Siebert, Mareike
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2020
Subjects: subject: Chlorogenic acid
subject: p-coumaroyl esterase
subject: coffee
subject: apple juice
subject: Chlorogensäure
subject: p-Cumarsäure
subject: Rhizoctonia solani
subject: Kaffee
subject: Apfelsaft
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: Kaffee und Fruchtsäfte gelten als Hauptaufnahmequelle von Chlorogensäuren. Insbesondere Kaffee weist hohe Konzentrationen des Isomers 5-O-Chlorogensäure (5-CQA) auf. Während die Rolle der 5-CQA als Vorstufe von Aroma-, Geschmacks- und Farbstoffen weitestgehend aufgeklärt ist, werden die Auswirkungen auf die Gesundheit kontrovers diskutiert. Unter anderem steht die 5-CQA im Verdacht, Sodbrennen und Magenbeschwerden nach Kaffeekonsum mitzuverusachen. Ziel dieser Arbeit war es folglich, die 5-CQA ohne Veränderung der sensorischen Eigenschaften zu minimieren. Durch enzymatische Behandlung mit einer p-Cumarsäureesterase aus Rhizoctonia solani wurde der Gehalt in geröstetem Kaffeepulver um 98 % reduziert. Die Aromaextraktverdünnungsanalyse ergab, dass sich lediglich vier Aromastoffe in ihrem flavour dilution factor (FDFaktor) zwischen behandeltem und unbehandeltem Kaffee unterschieden. Zudem wurden weder ein Fehlgeruch noch ein Fehlgeschmack wahrgenommen. Sensorische Tests bestätigten keinen signifikanten Unterschied. In einem weiteren Versuch wurde der enzymatische Behandlungsprozess auf das aufgebrühte Kaffeegetränk erfolgreich übertragen und optimiert. Verringerung der Inkubationszeit und –temperatur führten zu einem nahezu kompletten Abbau der 5-CQA nach 60 min und zu einer Abnahme um 89 % nach 30 min bei Raumtemperatur. Es wurden ebenfalls keine signifikanten sensorischen Unterschiede ermittelt. Um den Prozess weiter zu optimieren, wurde die RspCAE auf mesoporösem Silika und aktivierten Agaroseperlen immobilisiert. Letztgenannte Technik wies eine anfängliche Umsatzrate der 5-CQA von 98 % auf, die nach 30 h noch über 80 % betrug. Um die Anwendungsvielfalt der RspCAE zu erschließen, wurde ein weiteres Getränk enzymatisch behandelt. In Apfelsaft, welcher einen deutlich niedrigeren pH-Wert (pH 3) als Kaffee (pH 6) besitzt, wurde die 5-CQA Konzentration erfolgreich um 61 % verringert (Raumtemperatur, 30 min). Dieses Ergebnis zeigt, dass die RspCAE auch in stark sauren Lebensmitteln 5-CQA hydrolysiert. Die Behandlung führte zu keinen Veränderungen der sensorischen Eigenschaften (p < 0,05), was eine hohe Substratspezifität verdeutlicht. Die durch die vorliegende Arbeit aufgezeigte hohe Substratspezifität und Stabilität der RspCAE bilden einen vielversprechenden Ansatz für weitere Anwendungen in der Lebensmittelindustrie, um die Qualität einzelner Lebensmittel zu verbessern.
Cosmological Perturbation Theory in $f(Q,T)$ Gravity
Creators: name: Nájera, Antonio
name: Fajardo, Amanda
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We developed the cosmological linear theory of perturbations for $f(Q,T)$ gravity, which is an extension of symmetric teleparallel gravity, with $Q$ the non-metricity and $T$ the trace of the stress-energy tensor. By considering an ansatz of $f(Q,T)=f_1(Q)+f_2(T)$, which has been broadly studied in the literature and the coincident gauge where the connection vanishes, we got equations consistent with $f(Q)$ gravity when $f_{T}=0$. In the case of the tensor perturbations, the propagation of gravitational waves was found to be identical to $f(Q)$, as expected. For scalar perturbations, outside the limit $f_T = 0$, we got that the coupling between $Q$ and $T$ in the Lagrangian produces a coupling between the perturbation of the density and the pressure. The presence of $T$ in the Lagrangian breaks the equation of the conservation of energy, which in turn breaks the standard $ρ' + 3\mathcal{H} (ρ+p) = 0$ relation. We also derived a coupled system of differential equations between $δ$, the density contrast and $v$ in the $\mathcal{H}<
description: 20 pages. Accepted by JCAP
Responsible Metrics – Verantwortlicher Umgang mit Metriken
Creators: name: Hauck, Reingis
Publisher: name: Berlin : DUZ Verlags- und Medienhaus GmbH
Year: 2019
Subjects: subject: Bibliometrics
subject: reporting requirements
subject: research information systems
subject: research evaluation
subject: Bibliometrie
subject: Berichtsanforderungen
subject: Forschungsinformationssysteme
subject: Evaluierung von Forschung
subject: Leitlinien
subject: Dewey Decimal Classification::000 | Allgemeines, Wissenschaft::020 | Bibliotheks- und Informationswissenschaft

description: In der jüngeren Vergangenheit ist ein zunehmendes Engagement von Beschäftigten an Hochschulen und außeruniversitären Forschungseinrichtungen in Richtung eines professionalisierten Forschungsinformationswesens festzustellen. Der Aufbau von Forschungsinformationssystemen (FIS) spielt dabei eine zentrale Rolle. Die Frage, wie sich dort zu erfassende Daten für die Hochschulsteuerung – insbesondere auf der Grundlage bibliometrischer Indikatoren – nutzen lassen, wird in Deutschland (noch) nicht aufgegriffen. International hat die Diskussion zum Umgang mit Metriken eine deutlich größere Dynamik. Der Beitrag greift diesen Diskussionsprozess auf und erläutert die aktuellen Empfehlungen zu einem verantwortlichen Umgang mit Metriken.
description: In the recent past, there has been an increasing investment in the implantation of current research information systems (CRIS) at research institutions. The question of how the research information can be used for university management - particularly based on bibliometric indicators - has not (yet) been addressed in Germany. Internationally, the discussion on how to deal with metrics in university governance and research assessment is much more dynamic. The paper takes up this discussion process and explains the current recommendations for responsible use of metrics. In the area of reporting from research information systems, it is absolutely necessary to ensure bibliometric expertise in order to avoid misapplications and instead gain real insight through extended analysis possibilities. The author points to the necessary professionalisation in the development of bibliometric services as part of research management and recommends further training and participation in the international networks. Institutional guidelines can provide a framework for the responsible use of metrics. Their creation should be a starting point for the discussion of the use of bibliometric indicators and their application scenarios.
[Rezension zu] Friedrich Weber, Birgit Hoffmann, Hans-Jürgen Engelking (Hgg.), Von der Taufe der Sachsen zur Kirche in Niedersachsen
Creators: name: Lütjen, Andreas
Publisher: name: Stuttgart : Verein für Württembergische Kirchengeschichte
Year: 2011
Subjects: subject: Evangelisch-Lutherische Landeskirche in Braunschweig
subject: Dewey Decimal Classification::200 | Religion, Religionsphilosophie
subject: Dewey Decimal Classification::900 | Geschichte und Geografie

description: Rezension zu: Friedrich Weber / Birgit Hoffmann / Hans-Jürgen Engelking (Hgg.), Von der Taufe der Sachsen zur Kirche in Niedersachsen. Geschichte der Evangelisch-lutherischen Landeskirche in Braunschweig. Braunschweig: Appelhans-Verlag, 2010. 928 S., III.
Structural and molecular characterization of lopinavir and ivermectin as breast cancer resistance protein (BCRP/ABCG2) inhibitors
Creators: name: Dutra, Julia De Paula
name: Scheiffer, Gustavo
name: Kronenberger, Thales
name: Gomes, Lucas Julian Cruz
name: Zanzarini, Isadora
name: Dos Santos, Kelly Karoline
name: Tonduru, Arun K.
name: Poso, Antti
name: Rego, Fabiane Gomes De Moraes
name: Picheth, Geraldo
name: Valdameri, Glaucio
name: Rotuno Moure, Vivian
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2023
Subjects: ABCG2
ABCG2 inhibitors
drug repositioning
lopinavir
ivermectin
molecular modelling

description: A current clinical challenge in cancer is multidrug resistance (MDR) mediated by ABC transporters. Breast cancer resistance protein (BCRP) or ABCG2 transporter is one of the most important ABC transporters implicated in MDR and the use of inhibitors is a promising approach to overcome the resistance in cancer. This study aimed to characterize the molecular mechanism of ABCG2 inhibitors identified by a repurposing drug strategy using antiviral, anti-inflammatory and antiparasitic agents. Lopinavir and ivermectin can be considered as pan-inhibitors of ABC transporters, since both compounds inhibited ABCG2, P-glycoprotein and MRP1. They inhibited ABCG2 activity showing IC50 values of 25.5 and 23.4 µM, respectively. These drugs were highly cytotoxic and not transported by ABCG2. Additionally, these drugs increased the 5D3 antibody binding and did not affect the mRNA and protein expression levels. Cell-based analysis of the type of inhibition suggested a non-competitive inhibition, which was further corroborated by in silico approaches of molecular docking and molecular dynamics simulations. These results showed an overlap of the lopinavir and ivermectin binding sites on ABCG2, mainly interacting with E446 residue. However, the substrate mitoxantrone occupies a different site, binding to the F436 region, closer to the L554/L555 plug. In conclusion, these results revealed the mechanistic basis of lopinavir and ivermectin interaction with ABCG2.
description: EXCLI Journal; 22:Doc1155; ISSN 1611-2156
Photorealistic rendering of unidirectional free-space invisibility cloaks
Creators: name: Halimeh, Jad C.
name: Wegener, Martin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Carpet or ground-plane invisibility cloaks hide an object in reflection and inhibit transmission by construction. This concept has significantly reduced the otherwise demanding material requirements and has hence enabled various experimental demonstrations. In contrast, free-space invisibility cloaks should work in both reflection and transmission. The fabrication of omnidirectional three-dimensional free-space cloaks still poses significant challenges. Recently, the idea of the carpet cloak has been carried over to experiments on unidirectional free-space invisibility cloaks that only work perfectly for one particular viewing direction and, depending on the design, also for one linear polarization of light only. Here, by using photorealistic ray tracing, we visualize the performance of four types of such unidirectional cloaks in three dimensions for different viewing directions and different polarizations of light, revealing virtues and limitations of these approaches in an intuitive manner.
description: 16 pages, 9 figures, journal paper
[Rezension zu] Mensing, Petra (Hg.), Seid alle herzlich gegrüßt, Eure Minnie
Creators: name: Lütjen, Andreas
Publisher: name: Stuttgart : Verein für Württembergische Kirchengeschichte
Year: 2018
Subjects: subject: Rezension
subject: Ahnenforschung
subject: Genealogie
subject: Familienforschung
subject: Dewey Decimal Classification::900 | Geschichte und Geografie

description: Rezension zu: Mensing, Petra (Hg.), Seid alle herzlich gegrüßt, Eure Minnie. Wedemark: Extra Verlagsgesellschaft, 2018, 182 S.
Empirical essays on different aspects of labor economics
Creators: name: Sonderhof, Katja Alena
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2010
Subjects: subject: Policy evaluation
subject: discrimination
subject: overweight
subject: Politikevaluation
subject: Diskriminierung
subject: Übergewicht
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::330 | Wirtschaft

description: [no abstract]
Empirical studies on early and higher education
Creators: name: Horstschräer, Julia
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2012
Subjects: subject: Economics of education
subject: early education
subject: higher education
subject: Bildungsökonomik
subject: Elementarbildung
subject: Hochschulforschung
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::370 | Erziehung, Schul- und Bildungswesen
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::330 | Wirtschaft

description: [no abstract]
Auditory Modulation of Multisensory Representations
Creators: name: Effenberg, Alfred O.
name: Hwang, Tong-Hun
name: Ghai, Shashank
name: Schmitz, Gerd
Publisher: name: Cham : Springer
Year: 2018
Subjects: subject: Interpersonal coordination
subject: Motor control
subject: Motor learning
subject: Movement sonification
subject: Multimodal integration
subject: Multimodal perception
subject: Perceptuomotor representation
subject: Dewey Decimal Classification::700 | Künste, Bildende Kunst allgemein::790 | Freizeitgestaltung, Darstellende Kunst

description: Motor control and motor learning as well as interpersonal coordination are based on motor perception and emergent perceptuomotor representations. At least in early stages motor learning and interpersonal coordination are emerging heavily on visual information in terms of observing others and transforming the information into internal representations to guide owns behavior. With progressing learning, also other perceptual modalities are added when a new motor pattern is established by repeated physical exercises. In contrast to the vast majority of publications on motor learning and interpersonal coordination referring to a certain perceptual modality here we look at the perceptual system as a unitary system coordinating and unifying the information of all involved perceptual modalities. The relation between perceptual streams of different modalities, the intermodal processing and multisensory integration of information as a basis for motor control and learning will be the main focus of this contribution. Multi-/intermodal processing of perceptual streams results in multimodal representations and opens up new approaches to support motor learning and interpersonal coordination: Creating an additional perceptual stream adequately auditory movement information can be generated suitable to be integrated with information of other modalities and thereby modulating the resulting perceptuomotor representations without the need of attention and higher cognition. Here, the concept of a movement defined real-time acoustics is used to serve the auditory system in terms of an additional movement-auditory stream. Before the computational approach of kinematic real-time sonification is finally described, a special focus is directed to the level of adaptation modules of the internal models. Furthermore, this concept is compared with different approaches of additional acoustic movement information. Moreover, a perspective of this approach is given in a broad spectrum of new applications of supporting motor control and learning in sports and motor rehabilitation as well as a broad spectrum of joint action and interpersonal coordination between humans but also concerning human-robot-interaction. The final publication is available at Springer via https://doi.org/10.1007/978-3-030-01692-0_20.
Seemer Bote, Nr. 278 (September 2023)
Creators: name: (:Unkn) Unknown
Publisher: name: Ortsverein Seen
Year: 2023
Subjects: subject: 070 Publizistische Medien, Journalismus, Verlagswesen
subject: 307 Gemeinschaften
subject: Seen (Winterthur)
subject: Ortsverein Seen
subject: Stadtteilkultur

description: Bis Nr. 91 (März 1987) unter dem Titel «Seener Boote» erschienen.
Probing nuclear activity versus star formation at z~0.8 using near-infrared multi-object spectroscopy
Creators: name: Almeida, Cristina Ramos
name: Espinosa, J. M. Rodriguez
name: Acosta-Pulido, J. A.
name: Alonso-Herrero, A.
name: Garcia, A. M. Perez
name: Rodriguez-Eugenio, N.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present near-infrared (NIR) spectroscopic observations of 28 X-ray and mid-infrared selected sources at a median redshift of z~0.8 in the Extended Groth Strip (EGS). To date this is the largest compilation of NIR spectra of active galactic nuclei (AGN) at this redshift. The data were obtained using the multi-object spectroscopic mode of the Long-slit Intermediate Resolution Infrared Spectrograph (LIRIS) at the 4.2m William Herschel Telescope (WHT). These galaxies are representative of a larger sample studied in a previous work, consisting of over a hundred X-ray selected sources with mid-infrared counterparts, which were classified either as AGN-dominated or host galaxy-dominated, depending on the shape of their spectral energy distributions (SEDs). Here we present new NIR spectra of 13 and 15 sources of each class respectively. We detect the H alpha line at > 1.5 sigma above the continuum for the majority of the galaxies. Using attenuation-corrected H alpha luminosities and observed Spitzer/MIPS 24 micron fluxes, and after subtracting an AGN component estimated using an AGN empirical correlation and multi-frequency SED fits, we obtain average star formation rates (SFRs) of 7+/-7 and 20+/-50 Msun/yr respectively (median SFRs = 7 and 5 Msun/yr). These values are lower than the SFRs reported in the literature for different samples of non-active star-forming galaxies of similar stellar masses and redshifts (M* ~ 10^11 Msun and z~1). In spite of the small size of the sample studied here, as well as the uncertainty affecting the AGN-corrected SFRs, we speculate with the possibility of AGN quenching the star formation in galaxies at z~0.8. Alternatively, we might be seeing a delay between the offset of the star formation and AGN activity, as observed in the local universe.
description: 24 pages, 15 figures, accepted for publication in MNRAS
Durch den Dschungel der Moleküle. Routenplaner für Ziele im Genom
Creators: name: Langowski, Jörg
Publisher: name: Ruperto Carola
Year: 2015

description: Bestimmte Proteine, sogenannte Transkriptionsfaktoren, haben die Aufgabe, im Zellkern Gene an- oder abzuschalten. Damit sie ihre Arbeit tun können, müssen sie sich durch einen Dschungel von Zellsaft-Molekülen kämpfen, zu ihrer Wirkstätte vordringen, das Erbmolekül entwirren und an vorbestimmter Stelle binden. Die Wege, die Transkriptionsfaktoren dafür einschlagen, und die Kooperationen, die sie hierzu eingehen müssen, sind noch wenig bekannt. Neue Mikroskopiertechniken bringen Licht in das Dunkel.
description: Ruperto Carola, Nr. 7 (2015): Schatten & Licht
Komplexität als Herausforderung. In den Tiefen des Gehirns
Creators: name: Meyer-Lindenberg, Andreas
name: Kelsch, Wolfgang
Publisher: name: Ruperto Carola
Year: 2015

description: Das menschliche Gehirn, heißt es, ist das komplexeste Gebilde des Universums. Milliarden von Nervenzellen bilden das Zentrum unserer geistigen und seelischen Fähigkeiten, sind verantwortlich für unser Denken und Fühlen, für unser Bewusstsein, unsere Intelligenz und unsere Fähigkeit, uns zu erinnern. Wie das Gehirn funktioniert, ist trotz aller bahnbrechenden Erkenntnisse noch immer ein Geheimnis. Eine neue Untersuchungsmethode, die „Optogenetik“, verspricht, dem Gehirn so manch ein lang gehütetes Geheimnis zu entlocken und neue Ansätze zu finden, um Hirnerkrankungen erfolgreich zu behandeln.
description: Ruperto Carola, Nr. 7 (2015): Schatten & Licht
MAC-ReconNet: A Multiple Acquisition Context based Convolutional Neural Network for MR Image Reconstruction using Dynamic Weight Prediction
Creators: name: Ramanarayanan, Sriprabha
name: Murugesan, Balamurali
name: Ram, Keerthi
name: Sivaprakasam, Mohanasankar
Publisher: name: arXiv
Year: 2021
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Convolutional Neural network-based MR reconstruction methods have shown to provide fast and high quality reconstructions. A primary drawback with a CNN-based model is that it lacks flexibility and can effectively operate only for a specific acquisition context limiting practical applicability. By acquisition context, we mean a specific combination of three input settings considered namely, the anatomy under study, undersampling mask pattern and acceleration factor for undersampling. The model could be trained jointly on images combining multiple contexts. However the model does not meet the performance of context specific models nor extensible to contexts unseen at train time. This necessitates a modification to the existing architecture in generating context specific weights so as to incorporate flexibility to multiple contexts. We propose a multiple acquisition context based network, called MAC-ReconNet for MRI reconstruction, flexible to multiple acquisition contexts and generalizable to unseen contexts for applicability in real scenarios. The proposed network has an MRI reconstruction module and a dynamic weight prediction (DWP) module. The DWP module takes the corresponding acquisition context information as input and learns the context-specific weights of the reconstruction module which changes dynamically with context at run time. We show that the proposed approach can handle multiple contexts based on cardiac and brain datasets, Gaussian and Cartesian undersampling patterns and five acceleration factors. The proposed network outperforms the naive jointly trained model and gives competitive results with the context-specific models both quantitatively and qualitatively. We also demonstrate the generalizability of our model by testing on contexts unseen at train time.
Employee and consumer related aspects of socially sustainable organizational and business development of horticultural enterprises in Germany
Creators: name: Meyerding, Stephan Gerhard Heinz
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2016
Subjects: subject: Social sustainability
subject: consumer marketing
subject: human resources management
subject: Soziale Nachhaltigkeit
subject: Konsumenten Marketing
subject: Dewey Decimal Classification::600 | Technik::650 | Management

description: [no abstract]
Employing PROs in economic evaluation studies on treatments of cancer patients with prescription medications
Creators: name: Liu, Jia
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2011
Subjects: subject: Cancer
subject: patient-reported outcomes
subject: prescription medication expenditures
subject: Krebs
subject: Ergebnismessung aus Sicht des Patienten
subject: verschreibungspflichtige Medikamentenausgaben
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit

description: [no abstract]
title: Metaphor scenarios in discourses on menopause
title: A critical metaphor study of online articles of women’s magazines and medical websites from Denmark and the US
titleType: Subtitle
Creators: name: Bogo Jorgensen, Pernille
Publisher: name: Lancaster University
Year: 2023

description: In this thesis, I identify and analyse metaphor scenarios which represent menopause and those experiencing it in selected articles from online women’s magazines and medical websites from Denmark and the US. My aim is to determine how metaphor scenarios convey beliefs, norms and values through information about a prevalent women’s health issue. I outline and identify four elements of metaphor scenarios: metaphoric expressions, agency, narrative structures, and appraisal. Through an analysis of these, I identify patterns of metaphoric schematicity, agency and appraisal, all of which contribute to the characterisation of menopause and those experiencing it. I observe differences between the genres and languages. I explain my findings by contrasting them with previous studies of metaphor in discourses on health and studies of menopause specifically. Further, I discuss my findings in relation to ideologies of health and health marketisation in the two cultures. I argue that discursive traces of the medicalisation of menopause are present across the data, but that the Danish medical website conveys the least commercialised view of health. This, I argue, is consistent with the public health model in Denmark. Compared to the metaphor scenarios on medical websites, those in the women’s magazines are more oriented towards outer signs of health, such as skin. The US magazines represent those experiencing menopause as empowered, while the Danish magazines represent a belief in fate. I conclude that the menopause and those experiencing it can be represented in many different ways, with some encompassing greater flexibility than others, which could be of value for articulating different experiences and values connected to this important health concern.
An optimization approach to kinetic model reduction for combustion chemistry
Creators: name: Lebiedz, Dirk
name: Siehr, Jochen
Publisher: name: arXiv
Year: 2013
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences
subject: 90C90, 80A30, 92E20

description: Model reduction methods are relevant when the computation time of a full convection-diffusion-reaction simulation based on detailed chemical reaction mechanisms is too large. In this article, we review a model reduction approach based on optimization of trajectories and show its applicability to realistic combustion models. As most model reduction methods, it identifies points on a slow invariant manifold based on time scale separation in the dynamics of the reaction system. The numerical approximation of points on the manifold is achieved by solving a semi-infinite optimization problem, where the dynamics enter the problem as constraints. The proof of existence of a solution for an arbitrarily chosen dimension of the reduced model (slow manifold) is extended to the case of realistic combustion models including thermochemistry by considering the properties of proper maps. The model reduction approach is finally applied to three models based on realistic reaction mechanisms: 1. ozone decomposition as a small test case; 2. simplified hydrogen combustion for comparison with another model reduction method; 3. syngas combustion as a test case including all features of a detailed combustion mechanism.
description: 20 pages, 7 figures
Darstellung und Struktur von (CH3NH3)3PrCl6. 2 H20
Creators: name: Runge, P.
name: Schulze, M.
name: Urland, W.
Publisher: name: Berlin : De Gruyter
Year: 1990
Subjects: subject: Crystal Structure
subject: Magnetism
subject: Preparation
subject: Tris(methylammonium) Praseodymium Hexachloride Dihydrate
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: (CH3NH3)3PrCl6 · 2 H2O has been prepared as light green, air sensitive crystals by the reaction of PrCl3·xH2O with [CH3NH3]Cl in ethanol. The compound was characterized by crystal structure determination. Crystal data: monoclinic space group I 2/a, Z = 8. Lattice constants: a = 1963.3(4), b = 925.9(3), c = 1954.3(4) pm, β = 90.56(1)°. The compound forms [PrCl4(H2O)2]--chains where two Pr3+-ions are connected via two chlorine atoms. The magnetic behaviour of (CH3NH3)3PrCl6· 2H2O has been studied.