cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: Cellular model of pathology
Creators: name: Haugen, A.C.
name: Di Prospero, N.A.
name: Meyer, J.N.
name: Collins, J.B.
name: Fischbeck, K.
name: Fannin, R.D.
name: Durr, A.
name: Halweg, C.
name: Parker, J.S.
name: Chou, J.
name: Van Houten, B.
Publisher: name: Public Library of Science
Year: 2010

description: The neurodegenerative disease Friedreich's ataxia (FRDA) is the most common autosomal-recessively inherited ataxia and is caused by a GAA triplet repeat expansion in the first intron of the frataxin gene. In this disease, transcription of frataxin, a mitochondrial protein involved in iron homeostasis, is impaired, resulting in a significant reduction in mRNA and protein levels. Global gene expression analysis was performed in peripheral blood samples from FRDA patients as compared to controls, which suggested altered expression patterns pertaining to genotoxic stress. We then confirmed the presence of genotoxic DNA damage by using a gene-specific quantitative PCR assay and discovered an increase in both mitochondrial and nuclear DNA damage in the blood of these patients (p<0.0001, respectively). Additionally, frataxin mRNA levels correlated with age of onset of disease and displayed unique sets of gene alterations involved in immune response, oxidative phosphorylation, and protein synthesis. Many of the key pathways observed by transcription profiling were downregulated, and we believe these data suggest that patients with prolonged frataxin deficiency undergo a systemic survival response to chronic genotoxic stress and consequent DNA damage detectable in blood. In conclusion, our results yield insight into the nature and progression of FRDA, as well as possible therapeutic approaches. Furthermore, the identification of potential biomarkers, including the DNA damage found in peripheral blood, may have predictive value in future clinical trials.
A survey of X-ray emission from 100 kpc radio jets
Creators: name: Schwartz, Daniel A
name: Marshall, Herman L
name: Worrall, Diana M
name: Birkinshaw, Mark
name: Perlman, Eric
name: Lovell, James E J
name: Jauncey, David
name: Murphy, David
name: Gelbord, Jonathan
name: Godfrey, Leith
name: Bicknell, Geoffrey
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We have completed a Chandra snapshot survey of 54 radio jets that are extended on arcsec scales. These are associated with flat spectrum radio quasars spanning a redshift range z=0.3 to 2.1. X-ray emission is detected from the jet of approximately 60% of the sample objects. We assume minimum energy and apply conditions consistent with the original Felten-Morrison calculations in order to estimate the Lorentz factors and the apparent Doppler factors. This allows estimates of the enthalpy fluxes, which turn out to be comparable to the radiative luminosities.
description: Conference Proceedings IAU Symposium No. 313, Extragalactic jets from every angle, pp. 219-224, 4 figures
D3.2_Patient Questionnaire for the economic evaluation of GerOnTe
Creators: name: Ferrara, Lucia
name: Ardito, Vittoria
name: Tozzi, Valeria Domenica
name: Tarricone, Rosanna
Publisher: name: Zenodo
Year: 2022
Subjects: economic evaluation
Resource use
Questionnaire

description: These questionnaires are linked to D3.2 "Protocol for the economic evaluation of Geronte model", which describes all the necessary steps to be followed in order to conduct the economic evaluation of Geronte. These questionnaires aim to collect some data on resource use during the 12 months of patient follow-up including all direct costs incurred in other hospitals than the clinical site participating in the trial and indirect costs (e.g. travel costs and opportunity costs).
Growth Pangs of a Microfinance Institution: Trying to speed ahead without going off-course
Creators: name: Durreen Shahnaz,
name: Savita Shankar,
Publisher: name: National University of Singapore
Year: 2010
Subjects: India
microfinance
social enterprise
sustainability
social responsibility

description: A development oriented microfinance institution based in Tamil Nadu, India, wants to grow without drifting away from its mission. The case gives students an opportunity to consider the dilemmas faced by social enterprises, when they aim for sustainable and socially responsible growth in competitive sectors such as microfinance.
Characterization of the proneural gene regulatory network during mouse telencephalon development
Creators: name: Gohlke, J.M.
name: Gradwohl, G.
name: Portier, C.J.
name: Parham, F.M.
name: Armant, O.
name: Parker, J.S.
name: Nguyen, L.
name: Guillemot, F.
name: Smith, M.V.
name: Castro, D.S.
name: Zimmer, C.
Publisher: name: BioMed Central Ltd.
Year: 2008

description: Background: The proneural proteins Mash1 and Ngn2 are key cell autonomous regulators of neurogenesis in the mammalian central nervous system, yet little is known about the molecular pathways regulated by these transcription factors. Results: Here we identify the downstream effectors of proneural genes in the telencephalon using a genomic approach to analyze the transcriptome of mice that are either lacking or overexpressing proneural genes. Novel targets of Ngn2 and/or Mash1 were identified, such as members of the Notch and Wnt pathways, and proteins involved in adhesion and signal transduction. Next, we searched the non-coding sequence surrounding the predicted proneural downstream effector genes for evolutionarily conserved transcription factor binding sites associated with newly defined consensus binding sites for Ngn2 and Mash1. This allowed us to identify potential novel co-factors and co-regulators for proneural proteins, including Creb, Tcf/Lef, Pou-domain containing transcription factors, Sox9, and Mef2a. Finally, a gene regulatory network was delineated using a novel Bayesian-based algorithm that can incorporate information from diverse datasets. Conclusion: Together, these data shed light on the molecular pathways regulated by proneural genes and demonstrate that the integration of experimentation with bioinformatics can guide both hypothesis testing and hypothesis generation.
Scaling variables and asymptotic profiles for the semilinear damped wave equation with variable coefficients
Creators: name: Wakasugi, Yuta
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35L71, 35B40

description: We study the asymptotic behavior of solutions for the semilinear damped wave equation with variable coefficients. We prove that if the damping is effective, and the nonlinearity and other lower order terms can be regarded as perturbations, then the solution is approximated by the scaled Gaussian of the corresponding linear parabolic problem. The proof is based on the scaling variables and energy estimates.
description: 33 pages, final version, to appear in J. Math. Anal. Appl
On Markushevich bases in preduals of von Neumann algebras
Creators: name: Bohata, Martin
name: Hamhalter, Jan
name: Kalenda, Ondřej F. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Functional Analysis (math.FA)
subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 46B26, 46L10

description: We prove that the predual of any von Neumann algebra is $1$-Plichko, i.e., it has a countably $1$-norming Markushevich basis. This answers a question of the third author who proved the same for preduals of semifinite von Neumann algebras. As a corollary we obtain an easier proof of a result of U.~Haagerup that the predual of any von Neumann algebra enjoys the separable complementation property. We further prove that the self-adjoint part of the predual is $1$-Plichko as well.
description: 13 pages
The idea of the walking dead in medieval historical texts with particular reference to the English examples
Creators: name: Ignatova, Polina
Publisher: name: Lancaster University
Year: 2020

description: This thesis explores the origins and purpose of the stories about restless corpses appearing in the medieval Latin sources created in England between the eleventh and the fifteenth centuries. By engaging with a wide variety of sources, including ancient texts, walking-dead stories created in medieval Europe and Iceland, early modern and modern collections of folk tales, medieval medical treatises, and excavation reports, this thesis endeavours to provide a new insight into the nature of the accounts about revenants appearing in medieval English sources. Walking-dead stories have been seen as the remnants of the pagan Germanic beliefs, the superstitions of the unlearned masses, which somehow found their way into the written narratives. By (1) studying these stories within the context of a wider variety of sources, in contrast to the previously accepted methodology of studying a walking-dead story only as a part of the work in which it appears, and (2) checking the available evidence for the existence of popular superstitions regarding the dangerous dead against a larger range of sources than has been done previously, this thesis challenges the traditional way of viewing the stories about wandering cadavers as originating from popular beliefs, and proposes and alternative point of view, namely, that walking-dead stories were composed by the learned authors on the basis of the earlier sources.
Profiling essential genes in human mammary cells by multiplex RNAi screening
Creators: name: Hannon, G.J.
name: Elledge, S.J.
name: Marran, K.
name: Silva, J.M.
name: Parker, J.S.
name: Chang, K.
name: Golding, M.
name: Silva, J.
name: Schlabach, M.R.
Publisher: name: American Association for the Advancement of Science
Year: 2008

description: By virtue of their accumulated genetic alterations, tumor cells may acquire vulnerabilities that create opportunities for therapeutic intervention. We have devised a massively parallel strategy for screening short hairpin RNA (shRNA) collections for stable loss-of-function phenotypes. We assayed from 6000 to 20,000 shRNAs simultaneously to identify genes important for the proliferation and survival of five cell lines derived from human mammary tissue. Lethal shRNAs common to these cell lines targeted many known cell-cycle regulatory networks. Cell line-specific sensitivities to suppression of protein complexes and biological pathways also emerged, and these could be validated by RNA interference (RNAi) and pharmacologically. These studies establish a practical platform for genome-scale screening of complex phenotypes in mammalian cells and demonstrate that RNAi can be used to expose genotype-specific sensitivities.
Radda Barnen Becomes Radda: From Donor Project to Sustainable Local Healthcare
Creators: name: Naeem Mohaiemen,
Publisher: name: National University of Singapore
Year: 2010
Subjects: India
social enterprise
aid dependency
aid agency
ngo

description: After Swedish funders pulled out of a health clinic in Bangladesh, a local team took over and managed to cut wasteful expenses, bring in revenue and reach break-even. The case offers a model for breaking aid dependency by running organizations with local talent and a focus on financial sustainability, but at the same time, it highlights the limits of expansion due to resource constraints and land ownership barriers.
Gene Expression Profiles as Markers of Aggressive Disease-EGFR as a Factor
Creators: name: Levy, S.
name: Dicker, A.P.
name: Chung, C.H.
name: Rodeck, U.
name: Slebos, R.J.
name: Parker, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: We previously reported that 43 (58%) of 75 head and neck squamous cell carcinoma (HNSCC) tumors harbor increased epidermal growth factor receptor (EGFR) gene copy numbers as determined by fluorescent in situ hybridization. In this study, an increased EGFR copy number was associated with decreased progression-free survival and overall survival of HNSCC patients. However, activated EGFR protein levels are difficult to quantify by immunohistochemistry and are subject to dynamic regulation, specifically receptor downregulation on ligand binding. Therefore, we generated an activated EGFR gene expression signature in an in vitro HaCaT keratinocyte model system to further study genes involved in the EGFR signaling pathway in HNSCC. The results from this model system have suggested that the activated EGFR signature might reflect the activated state of the EGFR pathway in human HNSCC tumors and that it is associated with the increased EGFR gene copy number by fluorescent in situ hybridization. Furthermore, the activated EGFR signature has provided additional leads, because they are related to co-regulated molecular pathways and associated gene products on activation of EGFR. These could be exploited to refine and optimize combination therapies to be used in conjunction with available EGFR inhibitors in individual HNSCC patients.
Mapping the long-term sequelae of Campylobacter, Norovirus, & ETEC Infections in Children
Creators: name: Lalika, Mathias
name: Zane, Gregory
name: Shrestha, Priyanka
name: Al-Shimari, Fatima
name: Drain, Paul K.
name: Pavlinac, Patricia
name: START Center
Publisher: name: Gates Open Research
Year: 2023

description: The START team conducted a literature review of published research to synthesize evidence around long-term sequelae of Campylobacter, Norovirus & ETEC infections among children < 5 years of age on linear growth, ponderal growth, weight gain, and neurodevelopment.
Manufacturing technologies for slide bushings from powder materials for lever brake systems of vehicles
Creators: name: Stankevics, P.
name: Mironovs, V.
name: Muracova, N.
Publisher: name: Agronomy Research
Year: 2020
Subjects: metal powder materials
pulsed compaction
slide bushings
article

description: Slide bushings made of metal powder materials are used in many parts of vehicles. The current trend is to reduce the unit cost of products, increase the durability of components and assemblies, and reduce the harmful effects on the environment. One of these solutions is the use of powder materials. In this article, we consider some manufacturing techniques for sliding bushings of a lever brake system of a rolling stock using one-sided and two-sided pressing, pulse and combined sealing. The areas of their rational use are demonstrated as well.
Bouncing universe with modified dispersion relation
Creators: name: Pan, Wen-Jian
name: Huang, Yong-Chang
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, employing the modified dispersion relation, we have derived the general modified Friedmann equations and the corresponding modified entropy relations for the Friedmann-Robertson-Walker (FRW) Universe. In this setup, we find that when the big bounce happens, its energy scale and its corresponding modified entropy behavior are sensitive to the value of $k$. In contrast to the previous work with $k=0$, our work mainly demonstrates that the bouncing behavior for the closed Universe with $k=1$ appears at the normal energy limit of the modified dispersion relation introduced, and when bouncing phenomenon is in presence, its modified entropy is just equal to zero. Surprisingly, when $k=-1$, the bouncing behavior is in absence.
description: 15pages, no figures, Typos corrected, an appendix added, some discussions and references added; 16pages, no figures, presentation improved; published in General Relativity and Gravitation
When the Poor Became Bankable: Microfinance Crisis in Andhra Pradesh
Creators: name: Shriya Mohan,
name: P Praveen Siddharth,
Publisher: name: National University of Singapore
Year: 2010
Subjects: India
Andhra Pradesh
microfinance
Grameen Bank
private microfinance institution
market-oriented model
social business
commericialisation

description: The success of Grameen Bank, founded by Muhammad Yunus, had led to the sprouting of microfinance institutions in India. The Grameen model provided financing support for income generation in remote areas where banks had been tardy in providing service and had historically seen high repayment rates. However, the microfinance sector in India underwent a change in its model in August 2009 when India’s largest private microfinance institution (MFI) raised funds from the public through an IPO, promising high rates of return. While this was condemned as commercialization of microfinance, the market-oriented model aimed to help more poor people by tapping the large pool of investor capital rather than the limited pool of donor or subsidized funds. The situation reached a crisis in October 2010 when there was a spate of farmer suicides in Andhra Pradesh, the microfinance capital of India. More shocking facts about the industry such as the exorbitantly high interest rates, intense competition among MFIs which had led to multiple loans being offered for consumption in addition to income generation and tight repayment schedules, came to light. The group-lending system which enforced repayment through social pressure had exacerbated the situation for women caught in debt traps. The Reserve Bank of India, the country’s central bank had to intervene urgently. This case raises questions of ethics, profit models for social businesses and regulation through government intervention.
Soil-Transmitted Helminths (STH) environmental surveillance: Final presentation
Creators: name: Albirar, Mohamed
name: LeDuc, Samantha
name: Sheahan, Will
name: Drain, Paul
name: START Center
Publisher: name: Gates Open Research
Year: 2023

description: The START team conducted a short literature review on known methods for STH environmental surveillance and produced a database. Known methods were categorized as isolation methods, conventional identification methods, molecular identification methods, and emerging identification methods. After aggregating STH surveillance methods, a Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis was conducted and methods were further evaluated qualitatively by Technical Feasibility, Operational Feasibility, Integration and Cost.
Influence of regional technologies of varying intensity on the bioproductivity of sod-podzolic medium loamy soil in the Central region of the Russian Federation
Creators: name: Viyugin, S.M.
name: Kuchumov, A.V.
name: Viyugina, G.V.
name: Terentyev, S.E.
name: Karamulina, I.A.
Publisher: name: Agronomy Research
Year: 2020
Subjects: agrochemical soil parameters
agroecological monitoring
soil bio-productivity
sod-podzolic soil
soil profile
regional technologies
organic technology
crops
six-field field grain and grass crop rotation
article

description: This study is oriented to elucidating the role of the basic elements of regional farming systems in soil-crop complex using agricultural technologies of different levels of cultivation of field crops in the Smolensk Region. As a result of monitoring carried out in 1991–2008 on a reference site located in the Smolensk Region, negative changes of soil profile were revealed. Degree of soil podzolization increased what contributed to its degradation. All genetic horizons demonstrated deterioration in the basic parameters of soil fertility. Many years of experience showed a significant influence of the elements of studied technologies on soil acidity parameters, on the level of available phosphorus and exchangeable potassium; the amount of humic compounds was, however, characterized by relative stability. According to the total grain harvest of winter rye, spring soft wheat and barley, as well as of the green mass of perennial and annual herbs, studied variants were ranged in the following order: intensive, organic, adaptive, and extensive. Organic technology is suitable for getting environmentally friendly products. Obtained results are recommended to be used in the development of regional technologies of various intensity for the bio-productivity of sod-podzolic medium loamy soil in the Central region of the Russian Federation, as well as in regions with similar soil and climatic conditions. Choice of particular variant is in each case determined by the baseline characteristics of soil, planned level of productivity and harvest quality, availability of material and monetary resources in the economy.
A THESIS SUBMITTED TO ADDISABABA UNIVERSITY SCHOOL OF COMMERCE IN A PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF ARTS IN HUMAN RESOURCE MANAGEMENT
Creators: name: TESFAYE MOLLA
Publisher: name: Zenodo
Year: 2017

description: The main purpose of this study was to evaluate the effect of

performance appraisal on employee motivation in the case of Major

General Hayelom Areya Military Academy. Causal research design

was used. As a result to analyze this relationship the researcher

mainly deployed mixed type of research design. 151 respondents were

selected representing a population of 243 using stratified random

sampling in each department. Self-Administer Drop off survey data

collection technique was used and Statistical Package for Social

Science (SPSS) software version 22.0 was employed to analyze and

present the data through the statistical tools, namely descriptive and

inferential analysis. Performance appraisal did not motivated

employees in the academy. Performance appraisal rating cannot be

considered as a technique that has a pos i t ive effect on work

performance and employee motivation. The performance appraisal

identifies performance problems to improve employee motivation and

job satisfaction. In general the research findings were Pas and PAM

had appositive relation with employees’ motivation.
Chance-Constrained Optimization in Contact-Rich Systems for Robust Manipulation
Creators: name: Shirai, Yuki
name: Jha, Devesh K.
name: Raghunathan, Arvind
name: Romeres, Diego
Publisher: name: arXiv
Year: 2022
Subjects: subject: Robotics (cs.RO)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: This paper presents a chance-constrained formulation for robust trajectory optimization during manipulation. In particular, we present a chance-constrained optimization for Stochastic Discrete-time Linear Complementarity Systems (SDLCS). To solve the optimization problem, we formulate Mixed-Integer Quadratic Programming with Chance Constraints (MIQPCC). In our formulation, we explicitly consider joint chance constraints for complementarity as well as states to capture the stochastic evolution of dynamics. We evaluate robustness of our optimized trajectories in simulation on several systems. The proposed approach outperforms some recent approaches for robust trajectory optimization for SDLCS.
description: 9 pages, 9 figures
RNA polymerase is poised for activation across the genome
Creators: name: Parker, J.S.
name: Zeitlinger, J.
name: Gilchrist, D.A.
name: Nechaev, S.
name: Shah, R.
name: Adelman, K.
name: Grissom, S.F.
name: Muse, G.W.
Publisher: name: Nature Publishing Group
Year: 2007

description: Regulation of gene expression is integral to the development and survival of all organisms. Transcription begins with the assembly of a pre-initiation complex at the gene promoter, followed by initiation of RNA synthesis and the transition to productive elongation. In many cases, recruitment of RNA polymerase II (Pol II) to a promoter is necessary and sufficient for activation of genes. However, there are a few notable exceptions to this paradigm, including heat shock genes and several proto-oncogenes, whose expression is attenuated by regulated stalling of polymerase elongation within the promoter-proximal region. To determine the importance of polymerase stalling for transcription regulation, we carried out a genome-wide search for Drosophila melanogaster genes with Pol II stalled within the promoter-proximal region. Our data show that stalling is widespread, occurring at hundreds of genes that respond to stimuli and developmental signals. This finding indicates a role for regulation of polymerase elongation in the transcriptional responses to dynamic environmental and developmental cues.
Bibliometric Analyses and Visualizations for Cases 1-7: New data-related roles for librarians: Using bibliometric analysis and visualization to increase visibility of research impact.   In Handbook of Research on Knowledge and Organization Systems in Library and Information Science.
Creators: name: Yu, Fei
name: Dodd, Adam
name: Mani, Nandita S.
name: Cawley, Michelle
name: Hayes, Barrie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2021

description: Visualizations associated with seven bibliometric analysis cases as described in book chapter: New data-related roles for librarians: Using bibliometric analysis and visualization to increase visibility of research impact. In Handbook of Research on Knowledge and Organization Systems in Library and Information Science. Mani, N.S., Hayes, B., Dodd, A., Yu, F., & Cawley, M. (2021). In press
Violation of the Wiedemann-Franz law as an evidence of the pseudogap in the iron-based superconductor Ba(Fe1-xCox)2As2
Creators: name: Matusiak, Marcin
name: Wolf, Thomas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Longitudinal and transverse transport coefficients of the Ba(Fe1-xCox)2As2 single crystals with x = 0, 0.045, 0.06 and 0.244 were measured in the temperature range 1.4 - 300 K and in magnetic fields up to 12.5 T. The resulting data were used to determine the temperature dependence of the Hall Lorenz number (Lxy) and its evolution with doping. Lxy is defined by the electronic contributions to the thermal and electrical conductivities and it is found to differ from its canonical behavior. This shows the emergence of a pseudogap in samples at intermediate doping.
description: 16 pages, 4 figures
The delivery of welfare in Singapore rethought - A case study of Social Service Offices
Creators: name: Vignesh Louis Naidu,
Publisher: name: National University of Singapore
Year: 2015
Subjects: Singapore
social service
state assistance
welfare delivery model

description: In 2013, the Minister of Social and Family Development announced the launch of Social Service Offices (SSOs). These SSOs were designed to make the provision of social assistance more accessible to Singapore’s needy. The Singapore government has traditionally been prudent with the provision of social assistance, fearing that it would erode the work ethic of her citizens. By launching the SSOs, the government has not shifted significantly from its emphasis; on self-reliance and individual savings, the family as the first line of support for the poor, the community as an important ‘helping hand’, and targeting state assistance at those that have no other means of support, but instead sought to overcome the cognitive limitations of Singapore’s needy.

This case study aims to understand the role played by SSOs in the delivery of social assistance to needy Singaporeans, and how it has deviated from the welfare delivery model previously adopted by the state.
Non-extended phase space thermodynamics of Lovelock AdS black holes in grand canonical ensemble
Creators: name: Mo, Jie-Xiong
name: Liu, Wen-Biao
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Recently, extended phase space thermodynamics of Lovelock AdS black holes has been of great interest. To provide insight from a different perspective and gain a unified phase transition picture, non-extended phase space thermodynamics of $(n+1)$-dimensional charged topological Lovelock AdS black holes is investigated detailedly in the grand canonical ensemble. Specifically, the specific heat at constant electric potential is calculated and phase transition in the grand canonical ensemble is discussed. To probe the impact of the various parameters, we utilize the control variate method and solve the phase transition condition equation numerically for the case $k=1,-1$. There are two critical points for the case $n=6,k=1$ while there is only one for other cases. For $k=0$, there exists no phase transition point. To figure out the nature of phase transition in the grand canonical ensemble, we carry out an analytic check of the analog form of Ehrenfest equations proposed by Banerjee et al. It is shown that Lovelock AdS black holes in the grand canonical ensemble undergo a second order phase transition. To examine the phase structure in the grand canonical ensemble, we utilize the thermodynamic geometry method and calculate both the Weinhold metric and Ruppeiner metric. It is shown that for both analytic and graphical results that the divergence structure of the Ruppeiner scalar curvature coincides with that of the specific heat. Our research provides one more example that Ruppeiner metric serves as a wonderful tool to probe the phase structures of black holes.
Justice as a Decolonial Process
Creators: name: Flaherty, Phoebe Margaret
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Power struggles make up the
fabric of human history, with
conflict and the desired dominance
of one society over another
staining much of the past. In many
ways, the contemporary global setting
is representative of centuries
of power struggles at the societal,
international, and ideological level.
Pursuits of power in the global community
have long been accompanied
by the exploitation and manipulation
of societies for the benefit of
an imperial power. Long before the
categories of first, second, and third
world countries were introduced to
the international community as an
organizational model for global order,
the West had been positioned at
the apex of international power dynamics.
Largely maintained by the
legacies of European colonialism,
the modern power dynamics of the
international community remain
rooted in modern conceptions of
Western superiority. Colonization,
therefore, is an exercise in these
power dynamics.
Working for the Worker? A Study of the Union Générale Tunisienne du Travail (UGTT)
Creators: name: Erfani, Ava
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: What does the existence
of a national trade
union mean? As a
form, the institution rose in popularity
and necessity after the Industrial
Revolution, and its multinational
presence has also depended
on the simultaneous proliferation of
the industrial sector in each country.
As labor was forced into modernity
via the leveraging of wages, so
too was the work force galvanized
to stave off the most glaring parts
of industrial working conditions by
means of the formation of trade and
labor unions. The existence of a national
trade/labor union in a modern
state is no new concept; many
developed countries have significant
proportions of their working populations
involved in a trade union.
However, the efficacy and impact
of these unions remains a point of contention.
Forward and inverse portfolio problems with a range of risk measures
Creators: name: Hao, Dawei
Publisher: name: University of Leicester
Year: 2023
Subjects: Uncategorized

description: Maximizing investment utilities and modelling investors’ risk preferences are central problems in various applications of financial risk management including investment science and portfolio theory in particular. In general, investors need to solve forward portfolio optimization problems to maximize investment utilities and solve inverse portfolio optimization problems to identify risk preferences. A forward portfolio optimization problem requests to minimize the risk of a portfolio subject to a budget constraint to obtain optimal trading strategies in terms of investment weights among financial assets. In fact, the forward portfolio optimization problem can be solved with a range of risk measures, such as CVaR and drawdown measures. In this thesis, the benchmark-based CVaR-deviation and the benchmark-based drawdown as new possible risk measures are firstly introduced and the forward portfolio optimization problem is also solved with both new risk measures. Additionally, deviation measures are also possible risk measures, which is a family of risk measures containing MAD and CVaR-deviation as special cases. Traditionally, as a drawback, the forward portfolio optimization problems with deviation measures can only be solved separately by these special cases. Thus, to eliminate the drawback, this thesis develops a new general framework to deal with the forward problem based on the common features of the deviation measure family. As a result, a general linear program for the minimization of general deviation measures is derived, subject to a linear constraint, and minimization of an arbitrary positively homogeneous convex functional, whose dual set is given by linear inequalities, possibly involving auxiliary variables. This allows to reduce to linear programming for individual and cooperative portfolio optimization problems with arbitrary deviation measures whose risk envelopes are given by a finite number of linear constraints. In contrast, an inverse portfolio optimization problem requests to determine the investor’s risk preference that can be represented as a certain class of risk measures which makes the given portfolio optimal. Usually, the inverse portfolio optimization problems are static. In this thesis, a dynamic inverse problem called robust inverse portfolio problem is firstly introduced. The robust inverse is solved with the mixed CVaR measure, whose result is relatively stable to represent the risk over shift-time periods. In addition, the inverse portfolio optimization problem with drawdown measure is also firstly addressed in this thesis. All these problems are demonstrated with examples.
Plan des gestion des données : Utiliser le modèle structuré de DMP OPIDoR
Creators: name: AKDOGAN, Meriç
Publisher: name: Zenodo
Year: 2024
Subjects: DMP
PDG
data management plan
plan de gestion des données
modèle structué
machine actionable
DMP OPIDoR
guide

description: Guide d'utilisation du modèle structuré de plan de gestion des données (DMP) avec DMP OPIDoR pour Sorbonne Université

Note :  Le téléchargement du guide permet de naviguer dans le document grâce aux liens du sommaire
Productivity challenges in Singapore Part 4
Creators: name: Hawyee Auyong,
Publisher: name: National University of Singapore
Year: 2015
Subjects: Singapore
labour productivity
unemployment
technological disruptions

description: This part covers the current challenges facing policymakers in light of slowing global demand and future technological disruptions to jobs and employment. Many of these challenges stem from policy responses to other problems in the past, such as rapid industrialisation through foreign investment to tackle high unemployment during the immediate post-independence years; suppressing domestic costs in order to remain competitive as other economies in the region mimicked Singapore’s export-oriented growth strategy; and the drive to maintain high GDP growth rates through large labour and capital imports. Singapore’s current policy challenges in labour productivity demonstrate how policymaking is extremely path dependent, and that care has to be taken when designing interventions to current challenges to minimise unintended consequences for future policymakers.
Dominick Grace - "Unorthodox Economic Revenge": Cerebus and Social Justice
Creators: name: Grace, Dominick
Publisher: name: University of the Arts London
Year: 2020
Subjects: subject: 199999 Studies in the Creative Arts and Writing not elsewhere classified
subject: FOS: Arts (arts, history of arts, performing arts, music)

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In High Society, Dave Sim uses Moon Roach as part of his strategy of critiquing the idea of the superhero as social justice warrior. Rather than an independent agent seeking "unorthodox economic revenge" for the oppressed masses, Moon Roach is co-opted by the system, becoming instead part of the machinery of oppression.
An Analysis of Zimbabwean Health Crises Since Independence
Creators: name: McClure, James
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: In 2007, the lowest average female
life expectancy in the
world was Zimbabwe, at just
thirty-four years of age. However,
over the span of the last decade
the estimated female life expectancy
has risen to sixty-four years. From
these measures, we can assume
that the quality of life for Zimbabweans
has significantly improved
in the last decade, yet quantitative
data does not paint the entire picture.
Today Zimbabwe remains the
eighth highest Human Immunodeficiency
Virus (HIV)-prevalent
nation in the world, despite a drop
from twenty-nine to fifteen percent
in the infection rate since its peak in
1997. A full understanding of the
seriousness of Zimbabwe’s health
crisis requires examination of the
history of Zimbabwe, changes in
its political leadership, and governmental
response to various disease
outbreaks. While Zimbabwean life
expectancy and health outcomes
have improved since the 2007 lows, high rates of infectious disease and
malnutrition remain due to gross
incompetence by former president
Robert Mugabe, as well as continuing
economic hyperinflation and
instability. Recurring authoritarian
tendencies of current president Emmerson
Mnangagwa suggest that he
is likely to repeat the same mistakes
as Mugabe.
Ideology, Narrative, and Adaptation: A Case Study of the Soviet War Memorials in Berlin
Creators: name: Alexander, Collins
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Berlin has a tumultuous past,
having been the capital of
Prussia and the German empire
before the democratic Weimar
Republic, overtaken by Nazi Germany,
followed by the Iron Curtain’s
divide, and finally a unified modern
Germany. Berlin’s public space
reflects its volatile history.1 Street
names, buildings, and monuments
document the rise and fall of Germany
over the nineteenth and twentieth
centuries.
Keeping the char kway teow cheap - At what price
Creators: name: Tan Shin Bin,
Publisher: name: National University of Singapore
Year: 2015
Subjects: Singapore
hawker centres
hawker policies
hawker food prices
management models
social enterprise

description: Hawker centres formed an integral part of Singapore’s food culture, and were traditionally celebrated as meccas for cheap food. In recent years however, hawkers and customers alike raised concerns over rising business costs, and the resultant increases in hawker food prices. Furthermore, younger Singaporeans seemed disinterested in becoming hawkers, threatening the survival of the sector. With these trends as a backdrop, in October 2011, the Singapore government announced that it would build ten more hawker centres, after a hiatus of 26 years. This move would increase the supply of stalls available, help push rental costs down, as well as cater for new growth areas around the island. The government also promised to test out different management models, including having non-profits run the new centres instead of government agencies. This case examines the following questions: “Why was it important for the Singapore government to ensure that the ten new hawker centres provided cheap food, and how could it do so?”
Revisiting fermion mass and mixing fits in the minimal SUSY $SO(10)$ GUT
Creators: name: Fukuyama, Takeshi
name: Ichikawa, Koji
name: Mimura, Yukihiro
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Supersymmetric $SO(10)$ grand unified models with renormalizable Yukawa couplings involving only ${\bf 10}$ and $\overline{\bf 126}$ Higgs fields have been shown to realize the fermion masses and mixings economically. In previous works, the sum rule of the fermion mass matrices are given by inputting the quark matrices, and the neutrino mixings are predicted in this framework. Now the three neutrino mixings have been measured, and in this paper, we give the sum rule by inputting the lepton mass matrices, which makes clear certain features of the solution, especially if the vacuum expectation values of ${\bf 126}+ \overline{\bf126}$ ($v_R$) are large and the right-handed neutrinos are heavy. We perform the $χ^2$ analyses to fit the fermion masses and mixings using the sum rule. In previous works, the best fit appears at $v_R \sim 10^{13}$ GeV, and the fit at the large $v_R$ scale ($\sim 10^{16}$ GeV) has been less investigated. Our expression of the sum rule has a benefit to understand the flavor structure in the large $v_R$ solution. Using the fit results, we perform the calculation of the $μ\to eγ$ process and the electric dipole moment of electron, and the importance of $v_R$ dependence emerges in low energy phenomena. We also show the prediction of the CP phase in the neutrino oscillations, which can be tested in the near future.
description: This is the version to be published in Phys.Rev.D. The old subsection of proton decay is discussed in a separate form, arXiv:1609.08640
Crescent Among the Stars: Islam and Islamphobia in the European Union
Creators: name: Ahmed, Labeeb
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Inside the European Union,
the rise in the number of
Muslims and increased fear
of Islam has increased tension and
is stalling the integration of Europe,
especially after the 2015 migrant
crisis. Outside of the European
Union (EU), Muslim-majority nations
such as Albania, Bosnia and
Herzegovina, and Turkey attempt to
be involved as members in a Union
often cited as a “Christian Club” by
critics for its lack of Muslim participation.
This paper is an attempt to
showcase Islam’s rise in the EU and
explain how EU integration suffers
due to Islamophobia, especially after
the 2015 crisis. To do this, I will
examine the history of Islam in Europe,
then examine the 2015 crisis,
and interpret poll data and opinions
on Muslims by Europeans today –
largely drawn from modern new
sources and non-partisan polling
organizations such as the Pew Research Center. The paper will end
with an explanation of how EU integration
is affected by touching on
divisions between the EU member
states, the departure of one in part
due to Islamophobia, and the refusal
of others in part because of their
Muslim culture.
Plan des gestion des données : Utiliser le modèle structuré de DMP OPIDoR
Creators: name: AKDOGAN, Meriç
Publisher: name: Zenodo
Year: 2022
Subjects: DMP
PDG
data management plan
plan de gestion des données
modèle structué
machine actionable

description: Guide d'utilisation du modèle structuré de plan de gestion des données avec DMP OPIDoR pour Sorbonne Université Note :  Le téléchargement du guide permet de naviguer dans le document grâce aux liens du sommaire
Asteroid family ages
Creators: name: Spoto, Federica
name: Milani, Andrea
name: Knezevic, Zoran
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: A new family classification, based on a catalog of proper elements with $\sim 384,000$ numbered asteroids and on new methods is available. For the $45$ dynamical families with $>250$ members identified in this classification, we present an attempt to obtain statistically significant ages: we succeeded in computing ages for $37$ collisional families. We used a rigorous method, including a least squares fit of the two sides of a V-shape plot in the proper semimajor axis, inverse diameter plane to determine the corresponding slopes, an advanced error model for the uncertainties of asteroid diameters, an iterative outlier rejection scheme and quality control. The best available Yarkovsky measurement was used to estimate a calibration of the Yarkovsky effect for each family. The results are presented separately for the families originated in fragmentation or cratering events, for the young, compact families and for the truncated, one-sided families. For all the computed ages the corresponding uncertainties are provided. We found 2 cases where two separate dynamical families form together a single V-shape with compatible slopes, thus indicating a single collisional event. We have also found 3 examples of dynamical families containing multiple collisional families, plus a dubious case. We have found 2 cases of families containing a conspicuous subfamily, such that it is possible to measure the slope of a distinct V-shape, thus the age of the secondary collision. We also provide data on the central gaps appearing in some families. The ages computed in this paper are obtained with a single and uniform methodology, thus the ages of different families can be compared, providing a first example of collisional chronology of the asteroid main belt.
Functional characterization of E3-ubiquitin ligases for improved drought tolerance – the case study of a rice ABA-responsive gene
Creators: name: Lourenço, TF
name: Duarte, V
name: Melo, F
name: Saibo, NJM
name: Oliveira, MM
Publisher: name: Zenodo
Year: 2022

description: Rice is one of the most important crops worldwide, being the primary source of calories for more than half of the world population and a very sensitive species to water deficit. The identification of important molecular mechanisms modulating drought response, for enhanced water and nutrient capture, will play a key role towards a more sustainable rice production. The Ubiquitin-Proteasome system (UPS) is a key regulator of the proteome pool and has been established as a potential candidate for crop improvement towards abiotic stress tolerance (Melo et al., 2021). Nevertheless, several of its components remain uncharacterized. In our group, we are following a candidate gene approach to identify and functionally characterize rice E3-ubiquitin ligases in stress response. After in silico analysis, we selected (and validated by RT-qPCR) 16 genes showing differential gene expression under stress. Among those, the most promising 4 were selected for a deeper functional characterization using both a knock-out (CRISPR/cas9 gene edition) and an overexpression approach. One of those genes, RiP4g, is up-regulated by ABA. To characterize its role in ABA signaling, we have performed germination and post-germination assays, using the KO and OX plants. These assays indicated that OX-RiP4g confers hypersensitivity and KO-RiP4g hyposensitivity to ABA. Furthermore, using a whole plant water loss assay, we observed a differential behavior that can involve RiP4g in the regulation of stomatal aperture through ABA sensitivity. Taken together, our results will enhance our understanding of the molecular mechanisms underlying the rice response to drought, particularly regarding the function of RiP4g.
International Human Rights Trailblazer: The Case of American Foreign Policy in Argentina’s ‘Dirty War’ Under the Carter Administration
Creators: name: Broome, Brittany
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Today, the United States’ hegemonic
position in international
affairs is undeniable.
In this role, the United States
government has claimed to be a
champion of human rights in the
world, though, the integrity of this
assertion is subject to much debate.
President Jimmy Carter played an
instrumental role in shaping how
the government considers international
human rights in its formulation
of a foreign policy agenda. A
key example of this phenomenon is
the Carter administration’s handling
of relations with Latin America,
specifically Argentina, during the
late 1970s and into the early 1980s—
a time when the governing military
junta was committing gross human rights atrocities.