cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Readdressing the hierarchy problem in a Randall-Sundrum scenario with bulk Kalb-Ramond background
Creators: name: Das, Saurya
name: Dey, Anindya
name: SenGupta, Soumitra
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We re-examine the fine tuning problem of the Higgs mass, when an antisymmetric two form Kalb-Ramond (KR) field is present in the bulk of a Randall-Sundrum (RS) braneworld. Taking into account the back-reaction of the KR field, we obtain the exact correction to the RS metric. The modified metric also warps the Higgs mass from Planck scale (in higher dimension) to TeV scale (on the visible brane) for a range of values of $kr$ exceeding the original RS value (where $k=$ Planck mass and $r=$ size of extra dimension). However, it requires an extraordinary suppression of the KR field density, indicating the re-appearence of the fine tuning problem in a different guise. The new spacetime also generates a small negative cosmological constant on the visible brane. These results are particularly relevant for certain string based models, where the KR field is unavoidably present in the bulk. We further show that such a bulk antisymmetric KR field fails to stabilize the braneworld.
description: 4 Pages, Revtex, 1 figure. Important changes and addition. Version to appear in Class. Quant. Grav. Letters
Evaluating the relationship of blood pressure, plasma angiotensin peptides and aldosterone with cognitive functions in patients with hypertension
Creators: name: Şen, Selçuk
name: Gürel, Nermin
name: Ufuktepe, Baran
name: Özünal, Zeynep Güneş
name: Büyüklü, Çağla
name: Üresin, Yağız
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: hypertension
subject: cognitive functions
subject: angiotensin
subject: aldosterone
subject: 610

description: Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin peptides and aldoste- rone with cognitive functions. Forty-one patients who were under treatment with the same antihypertensive med- ications for at least three months were included in the study. Plasma angiotensin II, angiotensin 1-7, angiotensin IV, and aldosterone concentrations were analyzed using an enzyme-linked immunosorbent assay (ELISA). Stand- ardized Mini Mental State Examination (SMMSE) was used to evaluate cognitive functions. When the participants were grouped according to their SMMSE scores (cut-off value: 26 points), we determined significant differences between systolic blood pressure (SBP) levels, diastolic blood pressure levels, plasma angiotensin II and angioten- sin 1-7 concentrations of the groups. When the participants were stratified according to their SBP levels (cut-off value: 140 mm Hg), we found significant differences in SMMSE scores and plasma angiotensin IV concentrations of the groups. A negative correlation between SBP and SMMSE scores and strong linear correlations among an- giotensin peptides levels were determined. The relationship found between SBP and SMMSE in the present study was compatible with the literature. Our 33 patients were using at least one angiotensin II receptor blocker (ARB). Regarding AT1 receptor blockage, the significant association between higher SMMSE scores and increased angi- otensin peptides may support a finding that ARBs prevent dementia and improve cognitive function. Further larger studies are needed to confirm and prove the relation of RAAS biochemical parameters with cognitive function.
description: EXCLI Journal;Vol. 16 2017
Στοχαστική βελτιστοποίηση επενδυτικών στρατηγικών και εφαρμογές σε συνταξιοδοτικά σχήματα
Creators: name: Κατσάρα, Αικατερίνη
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Βέλτιστη επενδυτική στρατηγική
subject: Βέλτιστο αξίωμα του Bellman
subject: Δυναμικός προγραμματισμός
subject: Επενδυτική στρατηγική lifestyle
subject: Συνταξιοδοτικά σχήματα
subject: Συνταξιοδοτικό σχήμα καθορισμένων εισφορών
subject: Σύνταξη
subject: Συνταξιοδότηση
subject: Χρηματοοικονομικός κίνδυνος
subject: Επενδυτικός κίνδυνος
subject: Καθαρός συντελεστής αναπλήρωσης
subject: Στοχαστικές διαδικασίες
subject: Μαρκοβιανές αλυσίδες
subject: Ράντες ζωής

description: Στην παρούσα διπλωματική εργασία αναλύουμε τον χρηματοοικονομικό κίνδυνο σε ένα συνταξιοδοτικό σχήμα καθορισμένων εισφορών, εφαρμόζοντας τις τεχνικές του δυναμικού προγραμματισμού με απώτατο στόχο την εύρεση μίας βέλτιστης επενδυτικής στρατηγικής για το μέλος του σχήματος. Προβαίνουμε σε χρήση τόσο των ενδιάμεσων στόχων όσο και του τελικού στόχου της συνταξιοδότησης, ο οποίος είναι άρρηκτα συνδεδεμένος με τον επιθυμητό καθαρό συντελεστή αναπλήρωσης. Επιπροσθέτως, λαμβάνουμε υπόψιν μας τον επενδυτικό κίνδυνο και τον κίνδυνο της προσόδου οι οποίοι αντιμετωπίζονται από το μέλος του συνταξιοδοτικού σχήματος βάσει των οποίων προχωρούμε σε πλήθος διαπιστώσεων. Τα κυριότερα συμπεράσματα στα οποία καταλήγουμε αναφέρονται στην καταλληλόλητα και σπουδαιότητα της γνωστής επενδυτικής στρατηγικής του “lifestyle” και στην υψηλή μεταβλητότητα του επιπέδου της σύνταξης, το οποίο επιτυγχάνεται από τον ασφαλισμένο στην περίπτωση ενός μεταβλητού συντελεστή μετατροπής της προσόδου.
Paradoxical effect of minocycline on established neuropathic pain in rat
Creators: name: Zarei, Malek
name: Sabetkasaei, Masoumeh
name: Moini-Zanjani, Taraneh
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: minocycline
subject: neuropathic pain
subject: microglia
subject: allodynia
subject: hyperalgesia
subject: rat
subject: 610

description: Neuropathic pain occurs after peripheral nerve damage, inflammation or infection. In this situation, microglial cells become activated and play a key role in producing pain. Minocycline (microglia inhibitor), was reported to reduce pain when used preventively. However, it seems that, when used after nerve injury, results in its pain reducing effects are different. In this regard, to assess the pain reducing differences of minocycline, neuropathic pain was induced by the ligation of the sciatic nerve in the rat which is recognized as chronic constriction injury (CCI) and minocycline was administered before and after sciatic nerve injury. Wistar male rats (200-250 g, n=6) were used in these experiments. Rats were distributed in various groups: vehicle-treated CCI (control), sham- operated and minocycline-treated CCI groups. In the first part of the experiment (pre-injury study), minocycline (10, 20, 30 and 40 mg/kg,) was injected one hour before surgery and then daily for two weeks. In the second part (post injury study), minocycline was administered: 1: at day one after nerve damage once a day to day 14, 2: at day seven after surgery and continued daily until day 14. Analgesimeter for thermal hyperalgesia and von Frey hairs for mechanical allodynia were used to evaluate pain behavior. Thermal hyperalgesia and mechanical allo- dynia were attenuated significantly, when minocycline used before surgery, while it was not able to reduce pain behavior administered after surgery. It seems that, in spite of what some previous studies have reported, here, minocycline is not able to attenuate established neuropathic pain.
description: EXCLI Journal;Vol. 16 2017
Patterning of sodium ions and the control of electrons in sodium cobaltate
Creators: name: Roger, M.
name: Morris, D. J. P.
name: Tennant, D. A.
name: Gutmann, M. J.
name: Goff, J. P.
name: Hoffmann, J. U.
name: Feyerherm, R.
name: Dudzik, E.
name: Prabhakaran, D.
name: Boothroyd, A. T.
name: Shannon, N.
name: Lake, B.
name: Deen, P. P.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: NaxCoO2 has emerged as a material of exceptional scientific interest due to the potential for thermoelectric applications, and because the strong interplay between the magnetic and superconducting properties has led to close comparisons with the physics of the high-Tc cuprates. The density, x, of the sodium in the intercalation layers can be altered electrochemically, directly changing the number of conduction electrons on triangular Co layers. Recent electron diffraction measurements reveal a kaleidoscope of Na+ ion patterns as a function of concentration. Here we use single-crystal neutron diffraction supported by numerical simulations to determine the long-range three-dimensional superstructures of these ions. We show that the sodium ordering and its associated distortion field are governed by pure electrostatics, and the organizational principle is the stabilization of charge droplets that order long range at some simple fractional fillings. Our results provide a good starting point to understand the electronic properties in terms of a Hubbard Hamiltonian taking into account the electrostatic potential from the Na superstructures. The resulting depth of potential wells in the Co layer is greater than the single-particle hopping kinetic energy. As a consequence, holes occupy preferentially the lowest potential regions and, therefore, the Na+ ion patterning plays a decisive role in the transport and magnetic properties.
description: 12 pages, 4 figures, new version published in Nature
Στρατηγικές σχεδιασμού και μεθοδολογία για την διασφάλιση του απορρήτου των δεδομένων
Creators: name: Μαρούλη, Ελπινίκη
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Privacy
subject: Ιδιωτικότητα
subject: Προστασία δεδομένων
subject: Εμπιστευτικότητα
subject: Στρατηγικές σχεδιασμού απορρήτου

description: Ένας από τους βασικούς κανόνες χρήσης δεδομένων για επιχειρηματικούς σκοπούς είναι τόσο απλός: η ποιότητα των αποφάσεών σας εξαρτάται σε μεγάλο βαθμό από την ποιότητα των δεδομένων σας. Ωστόσο, απλά γνωρίζοντας ότι δεν είναι εξαιρετικά χρήσιμο. Για να έχετε απτά αποτελέσματα, θα πρέπει να μετρήσετε την ποιότητα των δεδομένων σας και να δράσετε σε αυτές τις μετρήσεις για να το βελτιώσετε. Εδώ, ρίχνουμε λίγο φως στα περίπλοκα ζητήματα ποιότητας δεδομένων και μοιραζόμαστε συμβουλές για το πώς να υπερέχουν στην επίλυσή τους.
Οι παίκτες στη λιμενική αγορά ε/κ της Μεσογείου και ο ρόλος των ελληνικών λιμανιών
Creators: name: Τικιντζή, Νικολέτα
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Μεσόγειος
subject: Εμπορευματοκιβώτια
subject: Λιμενική βιομηχανία
subject: Εταιρείες τακτικών γραμμών
subject: Μερίδια αγοράς
subject: Ελληνικά λιμάνια

description: Στην παρούσα εργασία εξετάζονται τα μέρη που δρουν στην αγορά διαχείρισης εμπορευματοκιβωτίων, τα οποία είναι οι ναυτιλιακές εταιρείες τακτικών γραμμών και οι εταιρείες διαχείρισης των τερματικών σταθμών εμπορευματοκιβωτίων. Στην αρχή αναλύονται οι σύγχρονες τάσεις στην ναυτιλία τακτικών γραμμών και στη λιμενική βιομηχανία των εμπορευματοκιβωτίων σε παγκόσμιο επίπεδο. Στη συνέχεια, προσεγγίζεται η γεωγραφική περιοχή της Μεσογείου και οι συμμαχίες των ναυτιλιακών εταιρειών που δρουν σε αυτήν. Μετέπειτα, αναλύεται η ζήτηση και η προσφορά στους κυριότερους μεσογειακούς λιμένες, καθώς και η παραγωγικότητα των συγκεκριμένων λιμένων ως προς βασικούς δείκτες. Η έρευνα ολοκληρώνεται με την εξαγωγή συμπερασμάτων που προκύπτουν ως προς τις εταιρείες διαχείρισης εμπορευματοκιβωτίων και ως προς τον λιμενικό ανταγωνισμό και προσδιορίζεται ο ρόλος που κατέχουν οι ελληνικοί λιμένες στην αγορά της Μεσογείου όσον αφορά τη διαχείριση εμπορευματοκιβωτίων.
Chemical composition and biological activities of Salvia officinalis essential oil from Tunisia
Creators: name: Ben Khedher, Med Raâfet
name: Ben Khedher, Saoussen
name: Chaieb, Ikbal
name: Tounsi, Slim
name: Hammami, Mohamed
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: salvia officinalis
subject: essential oil
subject: antioxidant
subject: antimicrobial activity
subject: insecticidal activity
subject: phytotoxicity
subject: 610

description: The aim of this study is to evaluate the chemical composition, antioxidant, antimicrobial, insecticidal and allelopa- thic activities of Tunisia Salvia officinalis essential oil (SoEO). The SoEO was characterized by the presence of 49 components with camphor (25.14 %), α-thujone (18.83 %), 1,8-cineole (14.14 %), viridiflorol (7.98 %), β-thu- jone (4.46 %) and β-caryophyllene (3.30 %) as the major components, determined by gas chromatography-mass spectrometry. The level of antioxidant activity, determined by complementary tests, namely 2,2-diphenyl-1-pic- rylhydrazyl radical-scavenging (IC50= 6.7 mg/mL), linoleic acid peroxidation (IC50= 9.6 mg/mL) and ferric reduc- ing assays (IC50= 28.4 mg/mL), was relatively moderate. The SoEO was also screened for its antimicrobial activity. Good to moderate inhibitions were recorded for most of tested microorganisms. It also exhibited important insec- ticidal activity against Spodoptera littoralis larvae and Tribolium castaneum adults with LC50 values of 55.99 and 97.43 µl/L air, respectively. The effect of the SoEO on seeds germination and growth showed different activities against radical and hypocotyl elongation of the tested species. These results suggest the potential use of the SoEO as natural antimicrobial preservative in cosmetic, pharmaceutical industry and in pest management.
description: EXCLI Journal;Vol. 16 2017
High level of miR-196b at newly diagnosed pediatric acute myeloid leukemia predicts a poor outcome
Creators: name: Xu, Lihua
name: Guo, Yang
name: Yan, Wenying
name: Cen, Jiannong
name: Niu, Yuna
name: Yan, Qing
name: He, Hailong
name: Chen, Chien-Shing
name: Hu, Shaoyan
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: miR-196b
subject: AML
subject: pediatric/child
subject: biomarker
subject: 610

description: Differential expression of microRNAs (miRNAs) has been implicated in leukemogenesis. We investigate the ex- pression pattern of miR-196b. Using quantitative real-time PCR (qRT-PCR), we detected the expression of miR- 196b and its correlated genes (SMC1A/MLH1) in initial pediatric AML. A significant association was observed between overexpression of miR-196b and inferior overall survival of pediatric AML (Log Rank P<0.0001). AML M4/5 subtype, high white blood cell (WBC) count at presentation, MLL rearrangement, or FLT3-ITD mutation at diagnosis and non-remission group after the first induction chemotherapy possessed higher miR-196b expression. Furthermore, a positive relationship was found between the expression of miR-196b and SMC1A/MLH1 (Spear- man’s r=0.37 and 0.44, P=0.001 and <0.0001, respectively). Taken together, these findings suggest that differen- tially high expression of miR-196b in diagnostic marrow samples of pediatric AML is associated with unfavorable outcome, and miR-196b potentially can be a novel biomarker for the diagnosis, prognosis and treatment in pediatric AML.
description: EXCLI Journal;Vol. 16 2017
Schnellwachsende Baumarten - Chance fur zusatzliches Einkommen im landlichen Raum?
Creators: name: Pallast, Gregor
name: Breuer, Thomas
name: Holm-Muller, Karin
name: Pallast, Gregor
name: Breuer, Thomas
name: Holm-Muller, Karin
Publisher: name: Unknown
Year: 2005
Subjects: subject: Community/Rural/Urban Development
subject: Farm Management
subject: Resource /Energy Economics and Policy
subject: short rotation Coppice
subject: farmers income
subject: renewable energy
subject: profitability
subject: rural areas

description: Based on previous experiences with the cultivation of short Rotation Coppice in Germany, the present article deals with the profitability of tree-plantations for bio-energy generation. The production process is divided into several steps in order to compare the resulting production costs with the associated revenues of potential users. As the cultivation of short rotating coppice in Germany is still in its experimental stage, the focus of this article is on the comparison of different production processes as well as on a critical evaluation of the available data base. The results show that - with no government aid taken into account - large scale cultivation can reach profitability only under very optimistic assumptions. Considering the necessary long term transaction-specific investments, a stable economic environment with secure sales is at least as important as financial aids. Ausgehend von den bisherigen Erfahrungen mit dem Anbau schnell wachsender Baumarten beschaftigt sich der vorliegende Artikel mit der Chance der kommerziellen Nutzung von Baumplantagen zur Erzeugung von Bioenergie in Deutschland. Hierzu wird die Produktion in einzelne Schritte gegliedert und monetar bewertet, um die daraus resultierenden Produktionskosten den moglichen Erlosen denkbarer Abnehmer entgegenzusetzen. Da der Anbau schnell wachsender Baumarten in Deutschland das Versuchsstadium noch nicht verlassen hat, liegt der Schwerpunkt auf dem Vergleich verschiedener Produktionsverfahren sowie einer kritischen Bewertung der verfügbaren Datengrundlage. Dabei zeigt sich, dass der Anbau in grossem Stil - die staatliche Forderung einmal ausgeklammert - nur bei sehr optimistischen Grundannahmen in die Nahe der Wirtschaftlichkeit ruckt. Zudem wird deutlich, dass auch finanzielle Hilfen ohne eine Planungssicherheit fur die notwendigen langfristigen und in hohem Masse faktorspezifischen Investitionen wenig bewirken werden. Schlusselworter : schnellwachsende baumarten, einkommensmoglichkeiten, erneuerbare energie, rentabilitat, landliche raume
Two Ways of Estimating a Transport Model
Creators: name: Jansson, Torbjorn
name: Jansson, Torbjorn
Publisher: name: Unknown
Year: 2005
Subjects: subject: Research Methods/ Statistical Methods
subject: spatial equilibrium
subject: transport model
subject: bi-level programming

description: In this article, it is shown how the parameters of a transport model can be estimated in a way that, in contrast to previously used methods, utilizes observations of regional prices as well as of trade costs. The proposed method uses bi-level programming to minimize a weighted least squares' criterion under the restriction that the estimated parameters satisfy the Kuhn-Tucker conditions for an optimal solution of the transport model. We use Monte-Carlo simulations to trace out some properties of the estimator and compare it with a traditional calibration method. The analysis shows that the proposed technique estimates prices as well as trade costs more efficiently.
Turbulence Statistics from Spectral Line Observations
Creators: name: Lazarian, A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Turbulence is a crucial component of dynamics of astrophysical fluids dynamics, including those of ISM, clusters of galaxies and circumstellar regions. Doppler shifted spectral lines provide a unique source of information on turbulent velocities. We discuss Velocity-Channel Analysis (VCA) and its offspring Velocity Coordinate Spectrum (VCS) that are based on the analytical description of the spectral line statistics. Those techniques are well suited for studies of supersonic turbulence. We stress that a great advantage of VCS is that it does not necessary require good spatial resolution. Addressing the studies of mildly supersonic and subsonic turbulence we discuss the criterion that allows to determine whether Velocity Centroids are dominated by density or velocity. We briefly discuss ways of going beyond power spectra by using of higher order correlations as well as genus analysis. We outline the relation between Spectral Correlation Functions and the statistics available through VCA and VCS.
description: 8 pages, 7 figures
Preparation and characterization of beta-glucan particles containing a payload of nanoembedded rifabutin for enhanced targeted delivery to macrophages
Creators: name: Upadhyay, Tarun K.
name: Fatima, Nida
name: Sharma, Deepak
name: Saravanakumar, V.
name: Sharma, Rolee
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: glucan particles
subject: targeted drug delivery
subject: spray drying
subject: macrophage
subject: rifabutin
subject: phagocytosis
subject: 610

description: β-glucan particles (GP) are polymeric carbohydrates, mainly found as components of cell wall fungi, yeast, bacteria and also in cereals such as barley and oat, and have been recently shown to have application in macrophagetargeted drug delivery. The aim of this study was to prepare and characterize GP containing a large payload of Rifabutin (RB), an anti-tuberculosis drug effective against MDR-TB at lower MIC than Rifampicin. GP were prepared from yeast cells by acidic and alkaline extraction were either spray dried or lyophilized, prior to RB loading and alginate sealing. The FTIR and 13C-NMR spectra of the GP confirmed a β-(1→3) linked glucan structure, with a triple-helical conformation. The spray dried GP exhibited better characteristics in terms of uniformity, size range (2.9 to 6.1 μm) and more than 75 % particles were below 3.5 μm. The RP-HPLC analysis of spray dried GP revealed drug entrapment and drug loading up to 81.46 ± 4.9 % and ~40.5 ± 1.9 %, respectively, as compared to those dried by lyophilization. Electron microscopy showed nearly spherical and porous nature of GP, and the presence of drug ‘nanoprecipitates’ filling the pore spaces. The formulation showed adequate thermal stability for pharmaceutical application. The particles were readily phagocytosed by macrophage(s) within 5 min of exposure. Drug release occurred in a sustained manner via diffusion, as the release kinetics best fit for drug release was obtained using Higuchi’s equation. Thus, the spray dried GP-based-formulation technology holds promise for enhanced targeted delivery of anti-TB drug(s) to macrophage within a therapeutic window for the clearance of intracellular bacteria.
description: EXCLI Journal;Vol. 16 2017
The World Agricultural Trade Simulation System WATSIM: An Overview
Creators: name: Von Lampe, Martin
name: Von Lampe, Martin
Publisher: name: Unknown
Year: 1998
Subjects: International Relations/Trade

description: This paper presents a general overview on the World Agricultural Trade Simulation System WATSIM, the international trade modelling system of the Institute for Agricultural Policy at Bonn University. The system consists of two submodels, dealing with two major aspects of agricultural world markets: In the medium term the impacts of changes in agricultural policies on regional and international markets are of major interest and hence are stressed in the Medium-Term Policy Simulation Model. Developments in natural and socio-economic variables become even more important for supply and demand of agricultural products in the longer run, depicted in the Long-Term Shift Factor Simulation Model. Before presenting the features of the two sub-models, the main characteristics of the system are briefly discussed, pointing out the importance of using both the database and the partial equilibrium module jointly. Dieses Diskussionspapier gibt einen kurzen Uberblick uber das World Agricultural Trade Simulation System WATSIM, das Handelsmodellsystem des Instituts fur Agrarpolitik der Universitat Bonn. Die beiden Sub-Modelle decken in ihrer zeitlichen und inhaltlichen Differenzierung zwei der wesentlichen Fragestellungen im Bereich der landwirtschaftlichen Weltmarkte ab: Wahrend mittelfristig der Einfluss veranderter Agrarpolitik im Vordergrund steht und deshalb Kern des Medium-Term Policy Simulation Model ist, gewinnen insbesondere auf langere Sicht Veranderungen naturlicher und soziookonomischer Rahmenbedingungen fur die Entwicklung auf den landwirtschaftlichen Markten an Bedeutung. Sie werden im Long-Term Shift Factor Simulation Model dargestellt. Bevor die Besonderheiten der beiden Sub-Modelle beschrieben werden, werden die wesentlichen Charakteristika des Modellsystems in Kurze dargestellt, wobei auf die Bedeutung der gemeinsamen Nutzung von Datenbasis und zentralem Modul zur Bestimmung des partialen Gleichgewichts durch beide Sub-Modelle hingewiesen wird.
Effects of symbiotic and vitamin E supplementation on blood pressure, nitric oxide and inflammatory factors in non-alcoholic fatty liver disease
Creators: name: Ekhlasi, Golnaz
name: Zarrati, Mitra
name: Agah, Shahram
name: Hosseini, Agha Fatemah
name: Hosseini, Sharieh
name: Shidfar, Shahrzad
name: Soltani Aarbshahi, Seyed Soroush
name: Razmpoosh, Elham
name: Shidfar, Farzad
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: Symbiotic
subject: Alpha-tocopherol
subject: Blood pressure
subject: Nitric oxide
subject: NAFLD
subject: 610

description: Non-alcoholic fatty liver disease (NAFLD) has been suggested to be well correlated with altered blood pressure. This study was conducted to determine the effects of symbiotic and vitamin E supplementation on blood pressure and inflammatory indices of patients with NAFLD. This randomized, double-blind, placebo-controlled trial was performed among 60 NAFLD patients aged 25 to 64 years old. Participants were randomly divided into four groups to receive a 400 IU alpha-tocopherol and 2 × 108 CFU/g symbiotic supplement for 8 weeks. The anthropometric parameters, systolic blood pressure (SBP) and diastolic blood pressure (DBP), serum malondialdehyde (MDA), nitric oxide (NO) and tumor necrosis factor α (TNFα) were assessed at baseline and after 8 weeks of intervention. After 8 weeks of intervention, combined symbiotic and alpha-tocopherol, symbiotic and alpha-tocopherol lone administration, compared with the placebo, resulted in significant decreases in SBP (-17.07±2.1, -16.07±3.56, -1.73±2.25 and -1.55±3.01 mmHg, P=0.01), serum MDA (-1.19±0.5, -0.12±0.65, 0.14 ± 0.64 and 0.16±0.34 nmol/mL, P<0.001), serum TNFα (-15.62±13.93, -9.24±7.12, -11.44 ± 15.47 and 3.01±1.71 pg/ml, P<0.001) concentrations. A significant decrease in serum AST (-11.36±4.52, -7.43±8.58, -5.93±6.61 and 2.5±5.75 μmol/L, P <0.001), ALT (-12.79±3.65, -3.66±6.81, -6.54±7.66 and 4.16±3.43 μmol/L, P <0.001) and ALP (-26.8±11.1, -4.56±9.22, -14.48±12.22 and 5.19±2.64 μmol/L, P <0.001) was seen. Variations in DBP and serum NO concentration were not significant. Alpha-tocopherol and symbiotic supplementation among patients with NAFLD resulted in decreased SBP, serum MDA, TNFα levels and enzymes liver; however, they did not affect DBP and serum NO concentration.
description: EXCLI Journal;Vol. 16 2017
Ανάλυση συνόλου ιατρικών δεδομένων MIMIC με ανάπτυξη εφαρμογής μηχανικής μάθησης, στο πλαίσιο πληροφοριακού συστήματος υγείας
Creators: name: Μεζίλη, Ελπίς
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Πληροφοριακά συστήματα
subject: Μηχανική μάθηση
subject: Ιατρικά δεδομένα
subject: MIMIC

description: Αντικείμενο της εργασίας αποτελεί η ανάλυση συνόλου ιατρικών δεδομένων MIMIC με ανάπτυξη εφαρμογής μηχανικής μάθησης, στο πλαίσιο πληροφοριακού συστήματος υγείας. Συγκεκριμένα, αποτελείται από τρία τμήματα. Αρχικά δημιουργήθηκε ένα πληροφοριακό σύστημα επικεντρωμένο στην πνευμονολογική κλινική του νοσοκομείου, στη συνέχεια μελετήθηκε το περιεχόμενο της βάσης δεδομένων MIMIC και αντλήθηκε το σχετικό με την πνευμονολογική κλινική μέρος των δεδομένων, και στο τέλος έγινε η ανάλυση τους, με την ανάπτυξη εφαρμογής μηχανικής μάθησης.
Seroepidemiological study of Toxoplasma gondii infection in a population of Iranian epileptic patients
Creators: name: Babaie, Jalal
name: Sayyah, Mohammad
name: Gharagozli, Kourosh
name: Mostafavi, Ehsan
name: Golkar, Majid
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: Epilepsy
subject: Toxoplasma gondii
subject: IgG
subject: ELISA
subject: Seroprevalence
subject: 610

description: Epilepsy is one of the most common neurologic disorders. Underlying cause of epilepsy is unknown in 60 % of the patients. Toxoplasma gondii is an intracellular parasite which is capable of forming tissue cysts in brain of chronically infected hosts including humans. Some epidemiological studies suggested an association between tox- oplasmosis and acquisition of epilepsy. In this study we determined seroprevalence of latent Toxoplasma infection in a population of Iranian epileptic patients. Participants were classified in three groups as Iranian epileptic patients (IEP, n = 414), non-epileptic patients who had other neurologic disorders (NEP, n = 150), and healthy people without any neurologic disorders (HP, n = 63). The presence of anti-Toxoplasma IgG antibodies and IgG titer in the sera were determined by ELISA method. Anti-T. gondii IgG seroprevalence obtained 35.3 %, 34.7 % and 38.1 % in IEP, NEP and HP, respectively. The seroprevalence rate was not significantly different among the three groups (P = 0.88). Anti-T. gondii IgG titer was 55.7 ± 78, 52.4 ± 74 and 69.7 ± 92 IU/ml in IEP, NEP and HP, respectively. There was not any statistically significant difference in the antibody titer between the study groups (P = 0.32). The rate of T. gondii infection in epileptic patients was not higher than non-epileptic patients and healthy people in the Iranian population.
Energy resolved STM mapping of C$_{60}$ on metal surfaces: A theoretical study
Creators: name: De Menech, Mario
name: Saalmann, Ulf
name: Garcia, Martin E.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present a detailed theoretical study of scanning tunneling imaging and spectroscopy of \Csixty on silver and gold surfaces, motivated by the recent experiments and discussion by X. Lu et al. [PRL \textbf{90}, 096802 (2003) and PRB \textbf{70}, 115418 (2004)]. The surface/sample/tip system is described within a self--consistent DFT based tight--binding model. The topographic and conductance images are computed at constant current from a full self--consistent transport theory based on nonequilibrium Green's functions and compared with those simulated from the local density of states. The molecular orbitals of \Csixty are clearly identified in the energy resolved maps, in close correspondence with the experimental results. We show how the tip structure and orientation can affect the images. In particular, we consider the effects of truncated tips on the energy resolved maps.
description: 9 pages, 8 figures
Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway
Creators: name: Jenwitheesuk, Anorut
name: Boontem, Parichart
name: Wongchitrat, Prapimpun
name: Tocharus, Jiraporn
name: Mukda, Sujira
name: Govitrapong, Piyarat
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: melatonin
subject: aging
subject: hippocampus
subject: sirtuin1
subject: FOXO1
subject: melatonin receptor
subject: 610

description: Sirtuin1 (SIRT1) and forkhead box transcription factor O subfamily 1 (FOXO1) play vital roles in the maintenance of hippocampal neuronal homeostasis during aging. Our previous study showed that melatonin, a hormone mainly secreted by the pineal gland, restored the impaired memory of aged mice. Age-related neuronal energy deficits contribute to the pathogenesis of several neurodegenerative disorders. An attempt has been made to determine whether the effect of melatonin is mediated through the SIRT1-FOXO1 pathways. The present results showed that aged mice (22 months old) exhibited significantly downregulated SIRT1, FOXO1, and melatonin receptors MT1 and MT2 protein expression but upregulated tumor suppressor protein 53 (p53), acetyl-p53 protein (Ac-p53), mouse double minute 2 homolog (MDM2), Dickkopf-1 (DKK1) protein expression in mouse hippocampus com- pared with the young group. Melatonin treatment (10 mg/kg, daily in drinking water for 6 months) in aged mice significantly attenuated the age-induced downregulation of SIRT1, FOXO1, MT1 and MT2 protein expression and attenuated the age-induced increase in p53, ac-p53, MDM2, and DKK1 protein and mRNA expression. Mel- atonin decreased p53 and MDM2 expression, which led to a decrease in FOXO1 degradation. These present results suggest that melatonin may help the hippocampal neuronal homeostasis by increasing SIRT1, FOXO1 and mela- tonin receptors expression while decreasing DKK1 expression in the aging hippocampus. DKK1 can be induced by the accumulation of amyloid β (Aβ) which is the major hallmark of Alzheimer’s disease.
description: EXCLI Journal;Vol. 16 2017
Deep Geometric Texture Synthesis
Creators: name: Hertz, Amir
name: Hanocka, Rana
name: Giryes, Raja
name: Cohen-Or, Daniel
Publisher: name: arXiv
Year: 2020
Subjects: subject: Graphics (cs.GR)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Recently, deep generative adversarial networks for image generation have advanced rapidly; yet, only a small amount of research has focused on generative models for irregular structures, particularly meshes. Nonetheless, mesh generation and synthesis remains a fundamental topic in computer graphics. In this work, we propose a novel framework for synthesizing geometric textures. It learns geometric texture statistics from local neighborhoods (i.e., local triangular patches) of a single reference 3D model. It learns deep features on the faces of the input triangulation, which is used to subdivide and generate offsets across multiple scales, without parameterization of the reference or target mesh. Our network displaces mesh vertices in any direction (i.e., in the normal and tangential direction), enabling synthesis of geometric textures, which cannot be expressed by a simple 2D displacement map. Learning and synthesizing on local geometric patches enables a genus-oblivious framework, facilitating texture transfer between shapes of different genus.
description: SIGGRAPH 2020
Ανάλυση αγοράς τηλεπικοινωνιών, τεχνολογιών LTE και WiMAX και τεχνοοικονομική ανάλυση WiMAX δικτύων
Creators: name: Δόγανος, Λεωνίδας
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Ανάλυση αγοράς τηλεπικοινωνιών
subject: Τεχνολογία LTE
subject: WiMAX
subject: Τεχνοοικονομική ανάλυση
subject: Ελληνική οικονομία

description: Σε αυτή τη διπλωματική εργασία ορίζεται ο κλάδος των τηλεπικοινωνιών κάνοντας μία ιστορική αναδρομή αλλά και θέτοντας κατηγορίες στην αγορά τους. Η σταδιακή απελευθέρωση αλλά και η διαρκώς αυξανόμενη ζήτηση τηλεπικοινωνιακών υπηρεσιών επιδρά θετικά στην ανάπτυξη της αγοράς. Οι τηλεπικοινωνίες αποτέλεσαν και αποτελούν έναν από τους κλάδους που ενισχύουν σημαντικά την οικονομία και επιδρούν άμεσα στο κοινωνικό-πολιτιστικό επίπεδο του πληθυσμού της χώρας. Γίνεται αναδρομή από τον τηλέγραφο του 19ου αιώνα μέχρι και τις οπτικές ίνες του 21ου . Όσον αφορά τις κατηγορίες της αγοράς τηλεπικοινωνιών αυτές ορίζονται σε τρεις τη σταθερή τηλεφωνία την κινητή τηλεφωνία και το διαδίκτυο. Στη συνέχεια αναλύεται η πορεία της αγοράς των ηλεκτρονικών επικοινωνιών παγκοσμίως, όπου υπάρχει μια συνεχής ανάπτυξη της βιομηχανίας ΤΠΕ (τεχνολογιών πληροφορικής και επικοινωνιών) καθώς η καθημερινότητα συνδέεται όλο και περισσότερο με την ψηφιακή εποχή. Εκτενέστερη ανάλυση γίνεται όσον αφορά την Ευρώπη και την Ελλάδα όπου εξετάζονται αναλυτικότερα η αγορά του εξοπλισμού καθώς και οι μελλοντικές επενδύσεις. Τέλος γίνεται σύγκριση της χώρας με την υπόλοιπη Ευρώπη στους κύριους παράγοντες των υπηρεσιών τηλεπικοινωνιών. Στο επόμενο κεφάλαιο γίνεται αναφορά στην αρχιτεκτονική και τα πρωτόκολλα του LTE όπου υπάρχει συνεχής εξέλιξη εδώ και χρόνια με τα δίκτυα 1ης, 2ης, 3ης και 4ης γενιάς. Γίνεται επίσης ανάλυση της ασύρματης τεχνολογίας WiMAX με έμφαση στα πρωτόκολλα και στα κύρια χαρακτηριστικά της. Στην τελευταία και σημαντικότερη ενότητα παρέχεται μια στρατηγική επισκόπηση της τεχνοοικονομικής ανάλυσης του WiMAX η οποία έχει σχεδιαστεί για να βοηθήσει μια ομάδα σχεδιασμού στρατηγικής για την ανάπτυξη ενός βιώσιμου επιχειρηματικού σχεδίου στην Ελλάδα. Το θέμα καλύφθηκε σε όσο το δυνατόν μεγαλύτερο εύρος και με όσο το δυνατόν πιο αξιόπιστα στοιχεία, αυτό προκύπτει διότι απαιτείται η εξέταση πολλών και διαφορετικών παραμέτρων τόσο στις τεχνολογικές απαιτήσεις για την υλοποίηση του προγράμματος όσο και στις οικονομικές. Πιο συγκεκριμένα για την υλοποίηση του έργου εξετάζονται και αναλύονται τα κύρια χαρακτηριστικά, αρκετές τεχνικές πληροφορίες από επιχειρηματική σκοπιά και οι ζώνες συχνοτήτων της WiMAX τεχνολογίας. Στην οικονομική ανάλυση αυτή γίνεται με την όσο το δυνατόν καλύτερη προσέγγιση καθώς αναλύονται το οικονομικό περιβάλλον και του κλάδου αλλά και της οικονομικής κατάστασης γενικότερα. Κατόπιν αφού βρεθούν παράγοντες όπως η κοστολόγηση, οι επιχειρησιακές και οι κεφαλαιουχικές δαπάνες αναλύονται οι σημαντικότεροι οικονομικοί δείκτες (KPIS) για να δικαιολογηθεί η έγκριση ή η απόρριψη του project.
TARGETING INDUSTRY CLUSTERS FOR REGIONAL DEVELOPMENT: AN OVERVIEW OF THE REDRL APPROACH
Creators: name: Barkley, David L.
name: Henry, Mark S.
name: Barkley, David L.
name: Henry, Mark S.
Publisher: name: Unknown
Year: 2002
Subjects: Industrial Organization

description: Industry targeting is the process of docusing industrial development programs and efforts at specific industries or clusters of related industries. The principal objectives of a industry targeting program is to identify: (1) industries that have a high potential for locating in the area, and (2) industries that provide attractive local economic development impacts in terms of future job growth, wages paid, and contributions to the local tax base. A targeting approach enables communities to focus their recruitment, retention and expansion, and small business development programs rather than provide assistance for many different industry types. Thus, targeting permits a more efficient use of the community's limited economic development resources.
Magnetic field effect on the superconducting magnetic gap of Nd{1.85}Ce{0.15}CuO4
Creators: name: Motoyama, E. M.
name: Mang, P. K.
name: Petitgrand, D.
name: Yu, G.
name: Vajk, O. P.
name: Vishik, I. M.
name: Greven, M.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Inelastic neutron scattering measurements on the archetypical electron-doped material Nd{1.85}Ce{0.15}CuO4 up to high relative magnetic field strength, H/Hc2 ~ 50%, reveal a simple linear magnetic-field effect on the superconducting magnetic gap and the absence of field-induced in-gap states. The extrapolated gap-closing field value is consistent with the upper critical field Hc2, and the high-field response resembles that of the paramagnetic normal state.
description: 4 pages, 3 figures; (v2) added reference; published in Phys. Rev. Lett
Nonlinear Protein Degradation and the Function of Genetic Circuits
Creators: name: Buchler, Nicolas E.
name: Gerland, Ulrich
name: Hwa, Terence
Publisher: name: arXiv
Year: 2005
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Biomolecules (q-bio.BM)
subject: FOS: Biological sciences

description: The functions of most genetic circuits require sufficient degrees of cooperativity in the circuit components. While mechanisms of cooperativity have been studied most extensively in the context of transcriptional initiation control, cooperativity from other processes involved in the operation of the circuits can also play important roles. In this study, we examine a simple kinetic source of cooperativity stemming from the nonlinear degradation of multimeric proteins. Ample experimental evidence suggests that protein subunits can degrade less rapidly when associated in multimeric complexes, an effect we refer to as cooperative stability. For dimeric transcription factors, this effect leads to a concentration-dependence in the degradation rate because monomers, which are predominant at low concentrations, will be more rapidly degraded. Thus cooperative stability can effectively widen the accessible range of protein levels in vivo. Through theoretical analysis of two exemplary genetic circuits in bacteria, we show that such an increased range is important for the robust operation of genetic circuits as well as their evolvability. Our calculations demonstrate that a few-fold difference between the degradation rate of monomers and dimers can already enhance the function of these circuits substantially. These results suggest that cooperative stability needs to be considered explicitly and characterized quantitatively in any systematic experimental or theoretical study of gene circuits.
description: 42 pages, 10 figures
Effects of hesperidin on formaldehyde-induced toxicity in pregnant rats
Creators: name: Merzoug, Sameha
name: Toumi, Mohamed Lamine
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: formaldehyde
subject: hesperidin
subject: pathophysiology
subject: behavior
subject: gestation
subject: fetal development
subject: 610

description: This experimental study aimed to investigate the protective effect of a bioflavonoid, hesperidin (HP), on formal- dehyde (FA)-related pathophysiological and behavioral outcomes in pregnant rats and developmental aspects in their offspring. Female Wistar rats were subjected to perigestational exposure to FA (2 mg/kg/day per os) with a concomitant treatment with HP (50 mg/kg/day per os). Pregnant rats were weighed throughout gestation and tested in two behavioral paradigms (elevated plus-maze and open field) at gestational days (GD) 1, 10 and 19 to evaluate the anxiety-like behavior and locomotive alterations. Another subset of rats was decapitated at GD19 to determine the hematological profile along with cortisol, 17β-estradiol, and progesterone plasma levels. Reproductive and fetal measures and observations were also performed to check for developmental deformities. Significant body weight loss, hemato-immune decline, hormonal changes, anxiety and lethargy signs, locomotor disabilities, repro- ductive failure and fetal weight decrease were observed in FA-exposed rats. Treatment with HP alleviated the reproductive and fetal weight defects. Its behavioral benefits were only seen at GD1 and 10. This flavanone ame- liorated some hematological parameters, decreased cortisol levels and increased 17β-estradiol rates. A potential preventive impact of HP was found against FA toxicity in pregnant rats.
description: EXCLI Journal;Vol. 16 2017
Γραμμική παλινδρόμηση για την πρόβλεψη της ανόδου ή πτώσης του χρηματιστηρίου
Creators: name: Δημανόπουλος, Μιχαήλ
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Μηχανική μάθηση
subject: Γραμμική παλινδρόμηση
subject: Πρόβλεψη χρηματιστηρίου

description: Σκοπός της παρούσας διπλωματικής εργασίας ήταν η ανάπτυξη και αξιολόγηση μοντέλου γραμμικής παλινδρόμησης για την πρόβλεψη της ανόδου ή πτώσης του παγκόσμιου χρηματιστηριακού δείκτη MSCI. Συγκεκριμένα, θεωρήσαμε ότι υπάρχει γραμμική συσχέτιση μεταξύ του παγκόσμιου χρηματιστηριακού δείκτη με τους πιο σημαντικούς χρηματιστηριακούς δείκτες ανά τον κόσμο και την πολικότητα των ειδήσεων (δηλαδή αν οι ειδήσεις ήταν θετικές ή αρνητικές). Οι δείκτες που μελετήθηκαν περιλαμβάνουν το Χρηματιστήριο Φρανκφούρτης (DAX), το Χρηματιστήριο Παρισιού (CAC 40), το Daw Jones, το Χρηματιστήριο Λονδίνου (FTSE 100), το NASDAQ και το S&P 500. Τα ευρήματα των πειραμάτων που πραγματοποιήθηκαν στα πλαίσια της εργασίας είναι ενδιαφέροντα τόσο για τους διάφορους χρηματιστηριακούς δείκτες που μελετήθηκαν όπως επίσης και για την συνεισφορά της επιπρόσθετης πληροφορίας από τα κείμενα που συλλέχθηκαν. Τέλος, την εργασία την συνοδεύει μία γραφική διεπαφή χρήστη, η οποία δίνει την δυνατότητα σε ενδιαφερόμενους να εκπαιδεύσουν τα δικά τους μοντέλα γραμμικής παλινδρόμησης, φορτώνοντας σύνολα εκπαίδευσης. Επίσης, οι ενδιαφερόμενοι μπορούν να προβλέψουν την άνοδο ή την πτώση του χρηματιστηρίου κάποια χρονική στιγμή δίνοντας πραγματικές τιμές στις ανεξάρτητες μεταβλητές.
ESTIMATING THE COMMUNITY-LEVEL IMPACTS OF ATTRACTING NEW BUSINESSES: THE IMPLICATIONS OF LOCAL LABOR MARKET ADJUSTMENTS
Creators: name: Barkley, David L.
name: Henry, Mark S.
name: Barkley, David L.
name: Henry, Mark S.
Publisher: name: Unknown
Year: 2002
Subjects: Labor and Human Capital

description: The purpose of this report is to estimate short-and long-run labor market adjustments associated with employment change for South Carolina counties. An appreciation of the source of employees for new jobs enables community leaders to better select the appropriate level of industrial incentives and to better plan for changes in demand for public goods and services. We provide an overview of the components of a local labor force and the implications of component change on local income and expenditures for public goods and services. Then we present the results of the Clemson University Community Policy Analysis (CPAN) Model for county labor markets. This model estimates the allocation of new jobs in a county among the components of a county's labor force. Third, we summarize the concepts of "job chains" and "leakages" and discuss the relationship between these concepts and community-level impacts. Finally, we conclude with a discussion of how insights into labor market adjustments may be used to improve public policy in community planning and industrial development.
EMPLOYMENT GENERATION STRATEGIES FOR SMALL TOWNS: AN OVERVIEW OF ALTERNATIVES
Creators: name: Barkley, David L.
name: Barkley, David L.
Publisher: name: Unknown
Year: 2001
Subjects: Labor and Human Capital

description: Employment growth is a primary economic development goal of most small communities. More jobs generally mean more residents, more spending at local businesses, and more tax revenues for local governments. Thus job growth permits the expansion and improvement of public goods and services, leading to an improved local quality of life and enhanced prospects for future employment growth. The purpose of this paper is to summarize the principal advantages and disadvantages associated with alternative employment generation strategies. The discussion of community approaches to more and better jobs is organized as follows. First, two theories of community economic growth are presented as background to the causes and effects of local employment change. Second, six employment generation strategies are introduced along with suggested plans of action for communities interested in implementing a specific strategy. Finally, a procedure is provided for incorporating an employment generation program in the community economic development strategic plan.