Assessment of endometrial CD-138 in women with infertility and its correlation with early pregnancy outcomes
Creators: name: UGHADE, PRACHI
Publisher: name: Zenodo
Year: 2023
Subjects: chronic endometritis, CD-138, infertility, early pregnancy outcomes.

description: <strong>Objective: </strong>To assess chronic endometritis and CD138 staining cells in endometrial tissues amongst infertile women. <strong>Design: </strong>The Department of OBGY, JNMC, AVBRH, DMIHER (Deemed University), Wardha district, will be undertaking this study. <strong>Setting: </strong>The investigation will take place among women seeking treatment for infertility; a total number of 60 women will be enrolled. List of the women undergoing IVF treatment will be obtained from respective sister incharge. <strong>Method: </strong>Self-prepared semi-structural questionnaire created and presented to gather information. We will select the infertile women’s by consecutive sampling method, those who fulfill the exclusion and inclusion criteria. To rule out any potential obstacles to the treatment, a thorough medical history will be collected. This includes obstetric assessment, along with a general, systemic, per abdominal and per vaginal examination. All Women seeking advance infertility treatment will be enrolled for study. All the participants will undergo Diagnostic laprohysteroscopy (premenstrual) or Endometrial biopsy (endometrial scratch on Day 21) prior to starting IVF treatment for advance fertile management. <strong>Outcome: </strong>Chronic endometritis is a generally hidden and challenging illness to detect. This study will provide insight into current practices in ivf and infertility treatment. <strong>Implications:</strong> This will encourage the participants for investigations, proper use of medications and improving hospital/facility outcome. Rate of CD138 in women seeking treatment of infertility. Correlation of CD138 positivity with β HCG, Urine pregnancy test, Clinical pregnancy, early pregnancy outcome, Live birth (if possible within study period).
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