cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: The reactivated intraplate Osning Lineament in northern Germany – Near-surface investigations using P- and SH-wave reflection seismics
Creators: name: Wadas, Sonja Halina
name: Tanner, David Colin
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2023

description:
Neotectonic movements can cause severe hazards and are scientifically and socially relevant for seismic hazard assessment and utilisation of the subsurface. In northern Germany, a presumed aseismic region, little is known about these processes and the associated structures, despite proven neotectonic activity, because many faults are hidden beneath sediments. To improve the knowledge of neotectonic activity, investigations of recently-active fault zones, like the Osning Lineament (OL) in North Rhine-Westphalia, are required.

To better understand the neotectonic evolution of the OL, we used a combined approach using high-resolution 2D P- and SH-wave reflection seismics to investigate four different sites at the Bielefeld-Segment of the OL. Overall, we acquired three P-wave profiles with which we were able to image the underground down to 700 to 800m depth, and four SH-wave profiles that imaged the subsurface down to 100m depth.

The seismic profiles show good results with respect to mapping the fault inventory. In the Cretaceous, Triassic, and Quaternary several, previously unknown, northward-dipping thrust faults are evident, which have upthrusted the formations toward the south. The faults form fault splays that developed due to the propagation of the OL into the footwall. The slow shear-wave velocities, especially in the Quaternary, allow for very high-resolution imaging of the subsurface and the identified faults are evidence for neotectonic activity. More to the south, we also observed some southward-dipping normal faults, which are interpreted as basin faults of the Münsterland Basin dipping towards the basin center.
title: Geochronology and trace element composition of zircon in granitoids from the Indus Syntaxis, northern Pakistan: new evidence for Palaeoproterozoic A-type magmatism in the north-western part of the Indian plate
Creators: name: Ahmad, Tanveer
name: Arif, Mohammad
name: Drüppel, Kirsten
name: Qasim, Muhammad
name: Sajid, Muhammad
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2023

description:
Two granitic plutons are exposed at Dubair and Shang in the vicinity of Besham, northern Pakistan, in the northwestern part of the Indian plate. Both granitoids mainly consist of perthitic feldspar, plagioclase, and quartz together with minor biotite, amphibole, and accessory ilmenite, apatite, titanite, and zircon. They are peraluminous and alkali-calcic to alkaline in composition, with strong A-type affinity (Ahmad et al., 2021). La-ICP-MS U-Pb dating and trace element analysis of zircon from both plutons were performed to elucidate their emplacement ages and temperatures. Most of the zircons are characterized by oscillatory zoning, depletion in light REE, and enrichment of heavy REE, with pronounced positive Ce and negative Eu anomalies. U–Pb zircon dating of the Shang and Dubair granitoid reveals similar concordant Palaeoproterozoic ages of 1871± 8.1 Ma and 1862 ± 7.5 Ma, respectively. The calculated Ti-in-zircon temperatures mainly range between 800°C and 900°C. The U-Pb ages, zircon compositions, and high magmatic temperatures suggest solidification of the granitoids from a crustal-derived magma emplaced during the Paleoproterozoic.

Reference

Ahmad, T., Arif, M., Qasim, M., & Sajid, M. (2021). Petrology of granitoids from Indus syntaxis, northern Pakistan: Implications for Paleo-Proterozoic A-type magmatism in north-western Indian Plate. Geochemistry, 81(1), 125693.
title: Constraining Respired Carbon Storage in the Eastern Tropical Pacific Over the Last 25 Thousand Years Using Benthic Foraminiferal Boron/Calcium Ratios
Creators: name: Close, Brian James
Publisher: name: Old Dominion University Libraries
Year: 2020

description: The storage of inorganic carbon in the deep Pacific Ocean is thought to play an important role in regulating both glacial-interglacial and millennial-scale atmospheric CO2 concentrations (Broecker and Barker 2007; Sigman et al., 2010). A recent study by Loveley et al. (2017) showed that sedimentary authigenic uranium (aU) concentrations, a proxy for suboxic bottom-water conditions, increased significantly in the Eastern Equatorial Pacific (EEP) during the Last Glacial Maximum (LGM, 18 kyr – 23 kyr). If this is correct, the low-oxygen, CO2-rich waters would also have a lower pH and a lower carbonate ion concentration ([CO32-]). Yu and Elderfield (2007) showed that the boron to calcium (B/Ca) ratio in the benthic foraminifera C. wuellerstorfi is a reliable proxy for reconstructing bottom water [CO32-]. Here I present new constraints on deep ocean carbon storage over the last 25 kyr in the EEP using new benthic foraminiferal B/Ca-[CO32-] reconstructions from four cores at a range of depths from within and outside the Panama Basin. These four new records all reveal lower glacial [CO32-], with the largest LGM-Holocene difference coming from core MV1014-02-17JC (17JC) (00°10.83’S, 85°52.00’W; 2.9 km water depth) inside the Panama Basin. New depth profiles of glacial carbon storage in the region show that respired CO2 storage outside the Panama Basin was relatively homogenous while inside the basin there was a gradient of increasing CO2 storage with depth from 2.2 km down to 2.9 km. A new sub-millennial scale record shows that during the last deglaciation (18 kyr - 11 kyr), waters inside the Panama Basin experienced two large increases in respired CO2 storage during Heinrich Stadial 1 and the Younger Dryas. Finally, intra-core proxy comparisons of 232Th (a dust flux proxy), excess barium (a paleoproductivity proxy), and aU from 17JC and MV1014-02-8JC (8JC) (6°14’N, 86°2’W; 2 km water depth) illustrate that two different mechanisms likely influenced CO2 storage in the region. For 8JC, a poorly ventilated Pacific wide water mass was likely the source for the lower glacial [CO32-] at its core location. While for 17JC, in addition to the previously noted poorly ventilated water mass influence, respired CO2 storage at this core location was further enhanced by millennial scale increases in export production. By sequestering carbon away from the atmosphere and surface ocean, deep waters in the Panama Basin and in the greater EEP region likely played an important role in lowering glacial atmospheric CO2.
title: Exploring for the Future: Officer Basin seal capacity analysis
Creators: name: A., Bailey
name: D., Dewhurst
Publisher: name: Commonwealth of Australia (Geoscience Australia)
Year: 2022
Subjects: subject: Geophysics not elsewhere classified
subject: EARTH SCIENCES
subject: Geology not elsewhere classified
subject: Petroleum and Coal Geology
subject: Published_External

description: This study was commissioned by Geoscience Australia (GA) to produce a report on seal capacity of select samples from wells in the Officer Basin of Western Australia and South Australia. Plugs were taken from the Giles-1, Yowalga-3, Vines-1 and Birksgate-1 wells and analysed via mercury injection capillary pressure testing. Results demonstrate that the analysed samples are capable of sealing very large columns of both methane and carbon dioxide.
Rana esculenta var. latastei Camerano. 1758
Creators: name: Müller, F
Publisher: name: Zenodo
Year: 1885
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Amphibia
Anura
Ranidae
Rana
Rana esculenta
Rana esculenta var. latastei camerano.

description: * Rana esculenta var. Latastei Camerano.
Marocco v. F M. [1]
description: Published as part of Müller, F, 1885, Vierter Nachtrag zum Katalogder herpetologischen Sammlung des Basler Museums, pp. 668-717 in Verhandlungen der Naturforschenden Gesellschaft in Basel. 7 (3) on page 670, DOI: 10.5962/bhl.part.2388, http://zenodo.org/record/15183591
title: Ruth & Lotte Jacobi. Fotografien. Ausstellungsrezension
Creators: name: Vitten, Anne
Publisher: name: ZZF - Centre for Contemporary History: Visual History
Year: 2021

description: Die Ausstellungsankündigung „Ruth & Lotte Jacobi“, die im Rahmen des EMOP Berlin – European Month of Photography 2020 präsentiert wurde, klingt vielversprechend: „Zum ersten Mal ist das fotografische Werk – bestehend aus Porträts, Stillleben, Reportagen, Lichtbildern und Experimentalaufnahmen – dieser vierten Generation einer jüdischen Fotografenfamilie in einer Ausstellung vereint.“ (Einführungstext) Selten haben Besucher*innen die Möglichkeit, sich Werke von Fotografinnen vergleichend anzusehen. Viel zu häufig werden diese als Einzelgängerinnen und Ausnahmen präsentiert.
title: A new tool to trace the redox-state of the upper mantle in the Archaean
Creators: name: Storey, Craig
name: Moreira, Hugo
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2023

description:
The redox state of the upper mantle in the Archaean through to the Proterozoic is a key parameter as it would have buffered atmospheric composition and interacted with the ocean-atmosphere system. There have been multiple approaches using geochemical proxies, such as V-Sc and redox sensitive stable isotopes (e.g. Fe) applied to mantle-derived rocks to investigate this problem. As whole rock samples are prone to overprinting (alteration, metamorphism) and as mafic rocks in particular are difficult to date, a technique using a robust U-bearing accessory mineral might allow better and more trustworthy temporal constraints to be measured. Recent work developing an oxybarometer based on S in apatite using µ-XANES has shown great promise as apatite can seamlessly incorporate reduced and oxidised S species and directly reflect the fugacity of host magmas. Nonetheless, apatite crystals in a matrix rock are prone to alteration and recrystallisation, but apatite inclusions trapped in zircon during magmatic crystallisation are robust, with the advantage that the enclosing zircon can be dated and the mantle source traced via Lu-Hf and O isotopes. To demonstrate that this approach works, we have studied 2.35 Ga TTGs and 2.13 Ga sanukitoids from the Mineiro Belt, Brazil. These rocks temporally straddle the Great Oxidation Event. Apatite inclusions in zircons from this TTG-sanukitoid transitional magmatic record reveal a change from reduced to more oxidised conditions from pre- to post-GOE. We then discuss how this approach has and can be further applied to Archaean rocks as a tracing tool for earlier oxygenation events.
Lesson of the month: novel method to quantify neutrophil uptake in early lung cancer using SPECT-CT
Creators: name: Farahi, Neda
name: Gillett, Daniel
name: Southwood, Mark
name: Rassl, Doris
name: Tregay, Nicola
name: Hill, Uta
name: Preston, Stephen Denis
name: Loutsios, Chrystalla
name: Lok, Laurence Si Chong
name: Heard, Sarah
name: Buscombe, John
name: Rintoul, Robert Campbell
name: Peters, A Michael
name: Summers, Charlotte
name: Chilvers, Edwin R
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Chest clinic
1506
2313
lung cancer
neutrophil biology
imaging/CT MRI etc

description: Neutrophils play an important role in the lung tumour microenvironment. We hypothesised that radiolabelled neutrophils coupled to single-photon emission CT (SPECT) may non-invasively quantify neutrophil uptake in tumours from patients with non-small cell lung cancer. We demonstrated increased uptake of radiolabelled neutrophils from the blood into tumours compared with non-specific uptake using radiolabelled transferrin. Moreover, indium-111-neutrophil activity in the tumour biopsies also correlated with myeloperoxidase (MPO)-positive neutrophils. Our data support the utility of imaging with In-111-labelled neutrophils and SPECT-CT to quantify neutrophil uptake in lung cancer.
Cerebral and spinal vascular involvement in Hereditary Hemorrhagic Telengiectasia: Report of two cases
Creators: name: Zeenat Qureshi Stroke Institutes
Publisher: name: Zenodo
Year: 2023

description: Introduction—We present two cases of Hereditary Hemmorhagic Telengiectasia (HHT), one pediatric and the other adult, with a view to highlight the myriad cerebral and spinal vascular manifestations of this disease. The syndrome and its various findings will be reviewed including the utility of angiography in assessing the various vascular abnormalities of the cerebral and spinal vasculature. Methods—A review of literature regarding various developmental abnormalities including brain and spinal cord arterio-venous malformations (AVMs), arterio-venous fistulae (AVFs), micro AVMs, micro-fistulae, aneurysms and cavernomas that occur in pediatric and adult population subsets of HHT. Both patients underwent thorough clinical and laboratory evaluation. The pediatric patient underwent a contrast enhanced computed tomography (CECT) of the chest; cerebral, Pulmonary & celiac angiography. The adult patient underwent cerebral and spinal angiography. Conclusion—The spectrum of vascular malformations in Hereditary Hemorrhagic Telengiectasia (HHT) is varied.The incidence and manifestations of brain and spinal cord AVMs, AVFs, micro AVMs, micro-fistulae, aneurysms and cavernomas are different in the pediatric and adults affected by the disease. Cerebral and spinal angiography are necessary in characterising the various developmental vascular abnormalities in order to guide further management.
Sprinkle coal dust on my grave
Creators: name: Williams, Walker Raymond
Publisher: name: University of British Columbia
Year: 2023

description: Sprinkle Coal Dust on my Grave is a musical composition for choir, vocal soloists, string orchestra, piano, percussion, fiddle, banjo, string bass, and narrator. Approximately 45 minutes in duration, it recounts the story of the Mine Wars, a period of early 20th century West Virginia labor history. The musical style of the composition draws inspiration from traditional Appalachian music as well as contemporary orchestral repertoire. The first chapter contains background on the composition, including a personal statement by the artist and a historical overview of the Mine Wars. The second chapter discusses the compositional materials used, including sections detailing the formal, harmonic, melodic, and textual aspects of the composition. The third chapter contains a detailed, movement-by-movement commentary on Sprinkle Coal Dust on my Grave. The fourth chapter concludes with a brief aesthetic statement. The full score is included as chapter five. The complete libretto is also included as appendix I.
Reflections on the uptake of the Python programming language in Nuclear and High-Energy Physics
Creators: name: Templon, Jeffrey
Publisher: name: Zenodo
Year: 2022
Subjects: Python
Nuclear Physics
High-energy physics

description: Python took a while to become an accepted language in High-Energy Physics. This short paper traces some of the history of this path to acceptance, and suggests some reasons for this apparently-slow uptake. Originally intended for the Pyhep 2018 Workshop.
description: None
Map #42, 5MT3875, Pit Room 131 and Nonstructure 119, Surface 1
Creators: name: DeVos, Jim
Year: 2018
Subjects: subject: Southwestern Colorado
valueUri: https://core.tdar.org/browse/geographic-keyword/2810/southwestern-colorado
subject: Southwestern US
valueUri: https://core.tdar.org/browse/geographic-keyword/84604/southwestern-us
subject: Basketmaker III
valueUri: https://core.tdar.org/browse/temporal-keyword/78/basketmaker-iii
subject: Pueblo II
valueUri: https://core.tdar.org/browse/temporal-keyword/55/pueblo-ii
subject: Shepherd Site
valueUri: https://core.tdar.org/browse/site-name/118016/shepherd-site
subject: 5MT3875
valueUri: https://core.tdar.org/browse/site-name/118017/5mt3875

description: 5MT3875, Pit Room 131 and Nonstructure 119, Surface 1
Impulsivity and compulsivity are differentially associated with automaticity and routine on the Creature of Habit Scale.
Creators: name: Ersche, Karen D
name: Ward, Laetitia H E
name: Lim, Tsen-Vei
name: Lumsden, Roderick J
name: Sawiak, Steven J
name: Robbins, Trevor W
name: Stochl, Jan
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Suppression
Frequency
Questionnaire
Personality Trait
Mediation
Goal-directed

description: Habits may develop when meaningful action patterns are frequently repeated in a stable environment. We measured the differing tendencies of people to form habits in a population sample of n = 533 using the Creature of Habit Scale (COHS). We confirmed the high reliability of the two latent factors measured by the COHS, automaticity and routines. Whilst automatic behaviours are triggered by context and do not serve a particular purpose or goal, routines often have purpose, and because they have been performed so often in a given context, they become automatic only after their action sequence has been activated. We found that both types of habitual behaviours are influenced by the frequency of their occurrence and they are differentially influenced by personality traits. Compulsive personality is associated with an increase in both aspects of habitual tendency, whereas impulsivity is linked with increased automaticity, but reduced routine behaviours. Our findings provide further evidence that the COHS is a useful tool for understanding habitual tendencies in the general population and may inform the development of therapeutic strategies that capitalise on functional habits and help to treat dysfunctional ones.
title: Finding opportunities in the uncertainties of geomechanical-numerical models
Creators: name: Ziegler, Moritz
name: Heidbach, Oliver
name: Reiter, Karsten
name: Rajabi, Mojtaba
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2023

description:
The numerical modelling of the in-situ stress state is commonly performed for reservoir management or subsurface applications such as nuclear waste repositories. Modelling is required due to the sparsity of available stress magnitude data records in addition to the uncertain underground structures and heterogeneous material properties. Even though, geomechanical models provide an increase in confidence and allow an interpretation of the in-situ stress state, the associated uncertainties are very high.

We present an approach where, instead of just one model scenario that is a best fit to all available data (but necessarily has a poor fit to some data records), a wide range of model scenarios that each satisfies at least one data record perfectly is estimated. Then, additional indirect data on the stress state or other manifestations are added in order to assess the predictive quality of each model scenario. These can be for example Formation Integrity Tests or Borehole Breakouts. While model scenarios that have a good agreement with indirect data are preferred, those that are largely in contradiction are neglected.

Eventually, this approach can be used to increase the knowledge on the subsurface. Of all things, remaining contradictions help to identify anomalies or geographical and lithological areas where the model is not representative (yet). This allows to improve and evolve the model in a data-based way not only based on geomechanics. Thus, adding uncertainties and further indirect data to the standard toolbox empowers the significance of a model.
Genomic risk scores for juvenile idiopathic arthritis and its subtypes
Creators: name: Cánovas, Rodrigo
name: Cobb, Joanna
name: Brozynska, Marta
name: Bowes, John
name: Li, Yun R
name: Smith, Samantha Louise
name: Hakonarson, Hakon
name: Thomson, Wendy
name: Ellis, Justine A
name: Abraham, Gad
name: Munro, Jane E
name: Inouye, Michael
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Rheumatoid arthritis
1506
2311
2502
arthritis
juvenile
polymorphism
genetic
rheumatoid

description: Objectives: Juvenile idiopathic arthritis (JIA) is an autoimmune disease and a common cause of chronic disability in children. Diagnosis of JIA is based purely on clinical symptoms, which can be variable, leading to diagnosis and treatment delays. Despite JIA having substantial heritability, the construction of genomic risk scores (GRSs) to aid or expedite diagnosis has not been assessed. Here, we generate GRSs for JIA and its subtypes and evaluate their performance. Methods: We examined three case/control cohorts (UK, US-based and Australia) with genome-wide single nucleotide polymorphism (SNP) genotypes. We trained GRSs for JIA and its subtypes using lasso-penalised linear models in cross-validation on the UK cohort, and externally tested it in the other cohorts. Results: The JIA GRS alone achieved cross-validated area under the receiver operating characteristic curve (AUC)=0.670 in the UK cohort and externally-validated AUCs of 0.657 and 0.671 in the US-based and Australian cohorts, respectively. In logistic regression of case/control status, the corresponding odds ratios (ORs) per standard deviation (SD) of GRS were 1.831 (1.685 to 1.991) and 2.008 (1.731 to 2.345), and were unattenuated by adjustment for sex or the top 10 genetic principal components. Extending our analysis to JIA subtypes revealed that the enthesitis-related JIA had both the longest time-to-referral and the subtype GRS with the strongest predictive capacity overall across data sets: AUCs 0.82 in UK; 0.84 in Australian; and 0.70 in US-based. The particularly common oligoarthritis JIA also had a GRS that outperformed those for JIA overall, with AUCs of 0.72, 0.74 and 0.77, respectively. Conclusions: A GRS for JIA has potential to augment clinical JIA diagnosis protocols, prioritising higher-risk individuals for follow-up and treatment. Consistent with JIA heterogeneity, subtype-specific GRSs showed particularly high performance for enthesitis-related and oligoarthritis JIA.
The significance of basin-scale indices to bottom conditions in the North Atlantic and adjacent shelf seas.
Creators: name: Johnson, Clare
name: Inall, Mark
name: Cunningham, Stuart
name: Biastoch, Arne
Publisher: name: Zenodo
Year: 2019

description: This presentation at hte 4th ATLAS General Assembly focused on deliverable D1.2, Ecosystem-relevant ocean flux, and discussed the significance of basin-scale indices to bottom conditions in the North Atlantic and adjacent shelf seas.
title: Gendered geographies of online gaming: a Brazil/UK comparative case study of gendered spatial practices of inclusion, exclusion and agency in the MOBA League of Legends
Creators: name: Dornelles, Vevila Rezende Costa
Publisher: name: University of Reading
Year: 2020

description: The digital, a complex assemblage of ontics, aesthetics, logics and discourses (Ash, Kitchin and Leszczynski, 2016), is now ingrained in geographical inquiries. Computer and videogames, genuinely geographical objects, appear at the vanguard of technology development, by connecting sophisticated works of art to entertainment and communication systems, arousing industries and markets around the Western world. Nevertheless, inequalities still haunt the access and advancement of digital technologies, creating absences and obscurities across the spaces of the digital, and that includes the realm of games. Scaffolded by a feminist standpoint, this research explores some aspects of digital inequalities by attending to how gendered spatial practices of inclusion, exclusion and agency are manifest within online gaming spaces. To examine these dynamics in their socio-cultural context, the massive online battle arena (MOBA) League of Legends was chosen as instrumental case study, where two different communities of players in Brazil and the United Kingdom were investigated. To answer the research question, a mixed-methods approach encompassing online surveys and semi-structured online interviews, informed by supportive participant observation, has provided rich quantitative and qualitative data. Abductive analysis, sustained by a multifaceted disciplinary conceptual framework, comprised descriptive statistics, content and thematic analysis. As a result, this research illuminates the nature of the gendered relations at play in the production of digital spaces of League, as well as the formation of homosocial spaces within the game. This innovative study has thus evidenced the gendered character of League of Legends’ spaces by unearthing the complex entanglements of identification and belonging, articulated and disputed through practices of antagonism and rapport enacted through online misbehaviour, homosociality and friendship. These findings have advanced the field of digital geographies by employing a feminist purchase to the production of digital spaces while expanding the contextual focus of game studies to Northern Europe and Latin America.
In vivo neuroinflammation and cerebral small vessel disease in mild cognitive impairment and Alzheimer’s disease
Creators: name: Low, Audrey
name: Mak, Elijah
name: Malpetti, Maura
name: Passamonti, Luca
name: Nicastro, Nicolas
name: Stefaniak, James D
name: Savulich, George
name: Chouliaras, Leonidas
name: Su, Li
name: Rowe, James B
name: Markus, Hugh S
name: O'Brien, John T
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Neuro-inflammation
1506

description: Introduction: Associations between cerebral small vessel disease (SVD) and inflammation have been largely examined using peripheral blood markers of inflammation, with few studies measuring inflammation within the brain. We investigated the cross-sectional relationship between SVD and in vivo neuroinflammation using [11C]PK11195 positron emission tomography (PET) imaging. Methods: Forty-two participants were recruited (according to NIA-AA guidelines, 14 healthy controls, 14 mild Alzheimer’s disease, 14 amyloid-positive mild cognitive impairment). Neuroinflammation was assessed using [11C]PK11195 PET imaging, a marker of microglial activation. To quantify SVD, we assessed white matter hyperintensities (WMH), enlarged perivascular spaces, cerebral microbleeds and lacunes. Composite scores were calculated for global SVD burden, and SVD subtypes of hypertensive arteriopathy and cerebral amyloid angiopathy (CAA). General linear models examined associations between SVD and [11C]PK11195, adjusting for sex, age, education, cognition, scan interval, and corrected for multiple comparisons via false discovery rate (FDR). Dominance analysis directly compared the relative importance of hypertensive arteriopathy and CAA scores as predictors of [11C]PK11195. Results: Global [11C]PK11195 binding was associated with SVD markers, particularly in regions typical of hypertensive arteriopathy: deep microbleeds (β=0.63, F(1,35)=35.24, p<0.001), deep WMH (β=0.59, t=4.91, p<0.001). In dominance analysis, hypertensive arteriopathy score outperformed CAA in predicting [11C]PK11195 binding globally and in 28 out of 37 regions of interest, especially the medial temporal lobe (β=0.66–0.76, t=3.90–5.58, FDR-corrected p (pFDR)=<0.001–0.002) and orbitofrontal cortex (β=0.51–0.57, t=3.53–4.30, pFDR=0.001–0.004). Conclusion: Microglial activation is associated with SVD, particularly with the hypertensive arteriopathy subtype of SVD. Although further research is needed to determine causality, our study suggests that targeting neuroinflammation might represent a novel therapeutic strategy for SVD.
Sociodemographic and lifestyle predictors of incident hospital admissions with multimorbidity in a general population, 1999–2019: the EPIC-Norfolk cohort
Creators: name: Luben, Robert
name: Hayat, Shabina
name: Wareham, Nicholas
name: Pharoah, Paul P
name: Khaw, Kay-Tee
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Epidemiology
1506
1692
epidemiology
health policy
social medicine

description: Background: The ageing population and prevalence of long-term disorders with multimorbidity are a major health challenge worldwide. The associations between comorbid conditions and mortality risk are well established; however, few prospective community-based studies have reported on prior risk factors for incident hospital admissions with multimorbidity. We aimed to explore the independent associations for a range of demographic, lifestyle and physiological determinants and the likelihood of subsequent hospital incident multimorbidity. Methods: We examined incident hospital admissions with multimorbidity in 25 014 men and women aged 40–79 in a British prospective population-based study recruited in 1993–1997 and followed up until 2019. The determinants of incident multimorbidity, defined as Charlson Comorbidity Index ≥3, were investigated using multivariable logistic regression models for the 10-year period 1999–2009 and repeated with independent measurements in a second 10-year period 2009–2019. Results: Between 1999 and 2009, 18 179 participants (73% of the population) had a hospital admission. Baseline 5-year and 10-year incident multimorbidities were observed in 6% and 12% of participants, respectively. Age per 10-year increase (OR 2.19, 95% CI 2.06 to 2.33) and male sex (OR 1.32, 95% CI 1.19 to 1.47) predicted incident multimorbidity over 10 years. In the subset free of the most serious diseases at baseline, current smoking (OR 1.86, 95% CI 1.60 to 2.15), body mass index >30 kg/m² (OR 1.48, 95% CI 1.30 to 1.70) and physical inactivity (OR 1.16, 95% CI 1.04 to 1.29) were positively associated and plasma vitamin C (a biomarker of plant food intake) per SD increase (OR 0.86, 95% CI 0.81 to 0.91) inversely associated with incident 10-year multimorbidity after multivariable adjustment for age, sex, social class, education, alcohol consumption, systolic blood pressure and cholesterol. Results were similar when re-examined for a further time period in 2009–2019. Conclusion: Age, male sex and potentially modifiable lifestyle behaviours including smoking, body mass index, physical inactivity and low fruit and vegetable intake were associated with increased risk of future incident hospital admissions with multimorbidity.
Map #58, Site 5MT2032, Topography
Creators: name: DeVos, Jim
Year: 2018
Subjects: subject: Southwestern Colorado
valueUri: https://core.tdar.org/browse/geographic-keyword/2810/southwestern-colorado
subject: Southwestern US
valueUri: https://core.tdar.org/browse/geographic-keyword/84604/southwestern-us
subject: Basketmaker III
valueUri: https://core.tdar.org/browse/temporal-keyword/78/basketmaker-iii
subject: 5MT2032
valueUri: https://core.tdar.org/browse/site-name/118020/5mt2032
subject: Switchback site
valueUri: https://core.tdar.org/browse/site-name/118019/switchback-site

description: Site 5MT2032, Topography
title: Experimental determination of boron isotope fractionation between silicate melts and hydrous fluids, with application to understanding magmatic-hydrothermal ore genesis
Creators: name: Rauscher, Jakob Heinrich
name: Wunder, Bernd
name: Wilke, Max
name: Trumbull, Robert
name: Jahn, Sandro
name: Sieber, Melanie Jutta
name: Michaud, Julie
name: Pohl, Florian
name: Scicchitano, Maria Rosa
name: Fechtelkord, Michael
name: Appelt, Oona
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2023

description:
The magmatic-hydrothermal transition is an important but poorly-understood process in the formation of Sn-W, Nb-Ta and Li deposits associated with evolved granites and pegmatites. Theory predicts that boron isotopes will fractionate between magma and fluid, so the magmatic-hydrothermal transition may be recorded in the borosilicate mineral tourmaline, which is widespread and common in these kinds of deposits. The key information needed to interpret the tourmaline record is the B-isotope fractionation between granitic melts and the fluids derived from them but former experimental studies on B-isotope fractionation between the relevant phases are not in agreement (e.g. Kowalski and Wunder, 2018, Maner and London, 2018).

This study fills this gap by an experimental, multivariant approach. We synthesized a glass of haplogranitic composition (Ab40Or25Qtz35) and produced variants of water content (0, 4 and 6 wt%), aluminum saturation (ASI 0.7, 1, 1.3) and boron concentration (2 and 5 wt%). For each composition we determined the coordination environment of B in the glass and the fractionation of B isotopes between the respective melt and aqueous fluid at near-solidus temperature. The first part of the study was the chemical characterization and analysis of B coordination in the glasses. The NMR analysis of 11B indicates that the coordination of 11B is dominantly trigonal in all glasses, but there is an increase of tetrahedral coordination with increasing boron concentration and water content. Fluid-melt fractionation experiments are ongoing and first results will be presented.
title: Geochemical, Petrophysical and Rock Mechanical Characterization of Crystalline Rocks in Germany for High-level Radioactive Waste Disposal – First Results of the AMPEDEK Project
Creators: name: Weydt, Leandra
name: Schedel, Markus
name: Ramírez, Ángel
name: Sass, Ingo
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2023

description:
The safe disposal of radioactive waste is a critical and frequently discussed topic in society. The Bundesgesellschaft für Endlagerung (BGE) was assigned with the selection of a suitable site for the disposal of high-level radioactive waste in Germany and, in the first phase of the selection procedure, has defined various selection criteria and sub-areas, seven of which cover the crystalline basement in Germany. For most of these sub-areas, little or no information is available on the crystalline host rocks and their properties, which would allow a narrowing of the site selection and identification of a suitable repository. Therefore, the AMPEDEK project establishes a reference database for the characterization of crystalline rocks in Germany. For this purpose, the database will contain information on the mineralogical, geochemical, petrophysical, and rock mechanical properties of predominantly igneous and metamorphic rocks of the Variscan basement. In the first phase, existing data from the literature or state geological offices were compiled and the structure of the database was established. In the second phase, ~500 drill cores and rock samples from quarries were analyzed in the laboratory to close existing data gaps. The goal was to sample as many different lithologies as possible to create a database that covers the majority of the relevant areas. The database currently contains ~8600 data points from 8 states and will be used to select smaller areas for Phase 2 of the site selection process and thus for detailed surface geological exploration campaigns.
title: The influence of burial and temperature history on hydraulic and hydro-mechanical properties of a Lower Jurassic (Pliensbachian) clay rock formation – First results of the MATURITY project
Creators: name: Winhausen, Lisa
name: Amann, Florian
name: Burchartz, Raphael
name: Erbacher, Jochen
name: Gaus, Garri
name: Grohmann, Sebastian
name: Jalali, Mohammadreza
name: Littke, Ralf
name: Luna, Ivan
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2023

description:
The characterization of potential host rocks for the final disposal of high-level radioactive waste is of great importance in the site selection procedure. For clay-rich host rocks, hydraulic and geomechanical characteristics often depend on the burial history determining the maximum effective stress and temperature (i.e., maturity), and the associated compaction as well as transformations during diagenesis. Therefore, the direct transferability of host rock properties between different regional-geological sites is challenging and requires detailed quantitative knowledge about host rock property variations at different maturity levels.

We present the first results of the “Maturity” research project that deals with a Lower Jurassic clay rock via field and laboratory investigations. The target formation of Pliensbachian age (182–190 Ma) is located in the Lower Saxony Hils Syncline and the neighboring Sack Syncline. Whereas the mineralogical composition can be considered similar, the clay rock is characterized by a large thermal maturation gradient over a relatively short lateral distance. The project involves shallow core drillings at five locations along the sequence of changing maturities and an extensive testing program. We explore the influence of thermal maturity on the i) hydraulic rock mass properties using in-situ single-hole and cross-hole hydraulic tests within fixed packer intervals, and ii) petrophysical and hydromechanical properties by conducting a variety of laboratory tests on core material. In this contribution, we present preliminary results of our field and lab testing campaigns including thermal maturity-dependent hydraulic rock mass and geochemical characteristics as well as porosity and mechanical strength determinations of the clay rock.
title: Diagnostics et approche de l’occupation du territoire et des types d’habitat à la Protohistoire ancienne : l’exemple du 1er âge du Fer dans le Nord et le Pas-de-Calais via le PCR HABATA
Creators: name: Henton, Alain
name: Leroy-Langelin, Emmanuelle
Publisher: name: Inrap
Year: 2021

description: Le diagnostic archéologique est un thème de colloque et de discussion récurrent. Si les aspects méthodologiques ont longtemps été au cœur des débats, il était opportun de traiter le sujet de manière différente. Le séminaire de Caen a permis de mettre en lumière les idées acquises et les problèmes rencontrés aujourd’hui par tous les acteurs de ces opérations archéologiques. Cet article tente de montrer comment les données issues de diagnostics s’intègrent dans un programme collectif de recherche (PCR). Afin de parvenir à une certaine exhaustivité, la période chronologique et l’aire géographique de ce programme ont été ici réduites. Après une présentation synthétique de ce dernier et du corpus d’étude défini, l’importance des données issues des opérations de diagnostic est soulignée à travers diverses thématiques : l’architecture des bâtiments, l’organisation des occupations, la culture matérielle et l’apport des données de diagnostics à sa connaissance.
description: Archaeological diagnostics is a recurring theme of colloquium and discussion. Although methodological aspects have long been at the heart of debates, it was appropriate to treat the subject in a different way. The Caen seminar highlighted the ideas acquired and the problems encountered today by all those involved in these archaeological operations. This article attempts to show how the data resulting from diagnostics fit into a collective research programme (PCR). In order to achieve a certain exhaustiveness, the chronological period and geographical area of this programme have been reduced here. After a summary presentation of it and of the defined corpus of studies, the importance of the data resulting from the operations of diagnostic is highlighted through various themes: architecture of buildings, organisation of occupations, material culture and contribution of diagnostic data to its knowledge.
Vietnam's renewables surge : securing future political legitimacy through eco-developmentalism.
Creators: name: Lee, Chaewon
Publisher: name: University of British Columbia
Year: 2023

description: Solar electricity generation in Vietnam has doubled yearly between 2018 and 2022, starting from 0.05% and growing to 10% of the nation's total electricity supply. Within the same period, Vietnam emerged as Southeast Asia's number one renewables market by accelerating its manufacturing and exports of solar panels. Given this "green tech boom," this thesis explores the drivers behind its "renewables leapfrogging," where Vietnam has rapidly scaled up its reliance on cleaner and greener energy sources in an extraordinarily short time. Moreover, the thesis examines why Vietnam, a lower middle-income nation, has actively invested in green technologies and challenged the Environmental Kuznets Curve (EKC) theory predicting that nations will pursue sustainable policies only once a high level of wealth has been met. While scholars have attributed the renewables surge to the nation's growing socioeconomic needs, an examination of local environmental issues, rising public discontent, and existential impacts of climate change illustrate how Vietnam's "green shift" reflects the Communist Party of Vietnam's (CPV) growing concerns over its future domestic political legitimacy. Until most recently, the regime's legitimacy has been attained and even strengthened through the exchange of liberal rights for the continued provision of socioeconomic benefits with the promise of fostering a higher standard of living for the people. However, worsening environmental concerns, further exacerbated by the nation's vulnerability to climate change, have begun to challenge this. The widespread issue of pollution has undermined citizens' health and, in some cases, prevented their access to their source of income. At the same time, heavy reliance on imported fossil fuels has escalated Vietnam's energy vulnerabilities and disrupted economic development. With much of the regime's authority dependent on its ability to continue positive economic performance amid worsening climate change, it has shifted its legitimation strategy to adopt "eco-developmentalism" as a somewhat desperate attempt to secure future political legitimacy by addressing long-term environmental and economic challenges. Therefore, under the eco-developmental framework, sustainable practices have been carefully formulated into the nation's economic strategies, prioritizing the renewables sector and other green policies that balance environmental protection alongside economic prosperity.
How achievable are COVID-19 clinical trial recruitment targets? A UK observational cohort study and trials registry analysis
Creators: name: Cunniffe, Nick G
name: Gunter, Simon J
name: Brown, Michael
name: Burge, Sarah W
name: Coyle, Clare
name: De Soyza, Anthony
name: Dymond, Tom
name: Esmail, Hanif
name: Francis, Darrel P
name: Galloway, Jacqui
name: Galloway, James B
name: Gkrania-Klotsas, Effrossyni
name: Greenaway, Jane
name: Katritsis, George
name: Kanagaratnam, Prapa
name: Knolle, Martin D
name: Leonard, Kelly
name: McIntyre, Zoe C
name: Prudon, Ben
name: Rampling, Tommy
name: Torok, Mili Estee
name: Warne, Ben
name: Yates, Mark
name: Matheson, Nicholas J
name: Su, Li
name: Villar, Sofia
name: Stewart, Grant D
name: Toshner, Mark
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Infectious diseases
1506
2474
1706
COVID-19
clinical trials
infectious diseases

description: Objectives: To analyse enrolment to interventional trials during the first wave of the COVID-19 pandemic in England and describe the barriers to successful recruitment in the circumstance of a further wave or future pandemics. Design: We analysed registered interventional COVID-19 trial data and concurrently did a prospective observational study of hospitalised patients with COVID-19 who were being assessed for eligibility to one of the RECOVERY, C19-ACS or SIMPLE trials. Setting: Interventional COVID-19 trial data were analysed from the clinicaltrials.gov and International Standard Randomized Controlled Trial Number databases on 12 July 2020. The patient cohort was taken from five centres in a respiratory National Institute for Health Research network. Population and modelling data were taken from published reports from the UK government and Medical Research Council Biostatistics Unit. Participants: 2082 consecutive admitted patients with laboratory-confirmed SARS-CoV-2 infection from 27 March 2020 were included. Main outcome measures: Proportions enrolled, and reasons for exclusion from the aforementioned trials. Comparisons of trial recruitment targets with estimated feasible recruitment numbers. Results: Analysis of trial registration data for COVID-19 treatment studies enrolling in England showed that by 12 July 2020, 29 142 participants were needed. In the observational study, 430 (20.7%) proceeded to randomisation. 82 (3.9%) declined participation, 699 (33.6%) were excluded on clinical grounds, 363 (17.4%) were medically fit for discharge and 153 (7.3%) were receiving palliative care. With 111 037 people hospitalised with COVID-19 in England by 12 July 2020, we determine that 22 985 people were potentially suitable for trial enrolment. We estimate a UK hospitalisation rate of 2.38%, and that another 1.25 million infections would be required to meet recruitment targets of ongoing trials. Conclusions: Feasible recruitment rates, study design and proliferation of trials can limit the number, and size, that will successfully complete recruitment. We consider that fewer, more appropriately designed trials, prioritising cooperation between centres would maximise productivity in a further wave.
title:   Ovid's Caeneus as a Queer Hero
title:  Understanding Gender and Gender Variance in the Ancient Mediterranean.
titleType: Subtitle
Creators: name: Palmer, RJ
Publisher: name: University of Kentucky Libraries
Year: 2023
Subjects: classificationCode: 6.2
subject: FOS: Languages and literature

description: Caeneus, as written in Ovid’s Metamorphoses, is a notable blend of ancient and Hellenistic versions of the myth. Ovid’s Caeneus can be understood as a transgender man, since he was assigned female at birth, but asks for his gender to be changed by the god Neptune, and goes on to live the rest of his life with the body, appearance, and social roles of a man. Ovid incorporates Caeneus’ trans identity with his use of grammatical gender endings for Caeneus, using masculine gender for Caeneus except when discussing his pre-transition childhood, or when the centaurs address him mockingly while fighting. This paper argues that Caeneus is not an exception to the Greco-Roman world, but rather Ovid is incorporating commonly held views of biology and gender from his own culture. His character can be analyzed, using modern queer theory methodology, in conjunction with research done on traditional third and fourth genders in other cultures. The goal is to better understand and conceptualize the ancient Greco-Roman world and its views on gender through literature and Ovid’s writing itself. By using these elements together, a broader model for discussing gender and gender variance in the ancient world can be proposed. Ovid’s model of Caeneus shows a functional and respectful way of discussing gender variant people, using literary and grammatical elements created by other authors.
description: © 2023 RJ Palmer
Visibilidad e impacto de Angola en circuitos comerciales de comunicación científica
Creators: name: United Nations Educational, Scientific and Cultural Organization
name: Ministério Do Ensino Superior, Ciência
name: Redalyc-Universidad Autónoma Del Estado De México
name: Amelica
name: Universidade Óscar Ribas
Publisher: name: Zenodo
Year: 2022
Subjects: Acceso Abierto
Angola
África
Mainstream
Scopus
Web of Science

description: Trabajo derivado del proyecto de colaboración entre Redalyc UAEM, AmeliCA, MESCTI y U. Óscar Ribas financiado por UNESCO para el desarrollo de una estrategia de Acceso Abierto en Angola. Vol. 4 de 38