cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Blood Cell Behavior in Hyperbolic Microchannels: Investigating the Cell Free Layer and Deformation
Creators: name: Yang, Lingyuan
Publisher: name: University of Illinois at Chicago
Year: 2024

description: Microfluidic systems have been successfully used in diverse biomedical applications, owing to their multitude advantages. These systems excel in working with minimal sample volumes and with short assays times. Moreover, microfluidic systems allow parallel operations, facilitating tasks like separation and deformation measurement of individual cell/particles. In microfluidic devices, cells can be effectively separated using two main methods for cells separation: passive methods, which are based on microstructures and laminar flow, and active methods that are driven by external force fields. The preference for passive methodologies is evident in numerous studies, given their autonomy from the need for external forces.
The primary aim of this study is to demonstrate the potential of employing microfluidic systems featuring hyperbolic microchannels for the separation of RBCs from plasma and to evaluate alterations in RBC deformability under physiological and pathological conditions, with a view to clinical applications. The protocol involves the initial separation of a specific quantity of RBCs from plasma, followed by deformability measurements on individual RBCs downstream. This research leverages soft lithography techniques to propose the design and fabrication of four distinct microfluidic devices, providing a foundation for comprehensive investigations into RBC deformability and its clinical implications.
The results show that the hyperbolic contractions with a higher Hencky strain, significantly enhance the CFL downstream of the contraction region. Regarding the cell deformability, the measurements indicate that RBCs are highly deformable under strong extensional flows, with the extent of deformability closely linked to flow rates and deformability indices (DI). Another important feature is the implementation of numerical simulation, which offer insights into mesh settings, quality, and their alignment with experimental results, enhancing our understanding of the underlying phenomena.
The endeavor to evaluate RBC deformability offers a strategic approach for the development of a straightforward, cost-effective, and user-friendly diagnostic tool for the detection and diagnosis of diseases related to red blood cells. The findings presented in this thesis underscore the efficacy of the hyperbolic microchannel as a viable method for integration into microfluidic systems, facilitating the continuous separation of cells from plasma.
A soft molecular 2Fe–2As precursor approach to the synthesis of nanostructured FeAs for efficient electrocatalytic water oxidation
Creators: name: Beltrán-Suito, Rodrigo
name: Forstner, Viktoria
name: Hausmann, J. Niklas
name: Mebs, Stefan
name: Schmidt, Johannes
name: Zaharieva, Ivelina
name: Laun, Konstantin
name: Zebger, Ingo
name: Dau, Holger
name: Menezes, Prashanth W.
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: oxygen evolution reaction
subject: transition-metal-complexes
subject: crystal-structure
subject: reaction dynamics
subject: redox states
subject: nickel foam
subject: iron-oxides
subject: ferrihydrite
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: An unprecedented molecular 2Fe-2As precursor complex was synthesized and transformed under soft reaction conditions to produce an active and long-term stable nanocrystalline FeAs material for electrocatalytic water oxidation in alkaline media. The 2Fe2As-centred beta-diketiminato complex, having an unusual planar Fe2As2 core structure, results from the salt-metathesis reaction of the corresponding beta-diketiminato (FeCl)-Cl-II complex and the AsCO- (arsaethynolate) anion as the monoanionic As- source. The as-prepared FeAs phase produced from the precursor has been electrophoretically deposited on conductive electrode substrates and shown to act as a electro(pre)catalyst for the oxygen evolution reaction (OER). The deposited FeAs undergoes corrosion under the severe anodic alkaline conditions which causes extensive dissolution of As into the electrolyte forming finally an active two-line ferrihydrite phase (Fe2O3(H2O)(x)). Importantly, the dissolved As in the electrolyte can be fully recaptured (electro-deposited) at the counter electrode making the complete process eco-conscious. The results represent a new and facile entry to unexplored nanostructured transition-metal arsenides and their utilization for high-performance OER electrocatalysis, which are also known to be magnificent high-temperature superconductors.
Instability of precession driven Kelvin modes: Evidence of a detuning effect
Creators: name: Herault, Johann
name: Giesecke, Andre
name: Gundrum, Thomas
name: Stefani, Frank
Publisher: name: arXiv
Year: 2018
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We report an experimental study of the instability of a nearly-resonant Kelvin mode forced by precession in a cylindrical vessel. The instability is detected above a critical precession ratio via the appearance of peaks in the temporal power spectrum of pressure fluctuations measured at the end-walls of the cylinder. The corresponding frequencies can be grouped into frequency sets satisfying resonance conditions with the forced Kelvin mode. We show that one triad is associated with a parametric resonance of Kelvin modes. For the first time, we observe a significant frequency variation of the unstable modes with the precession ratio. We explain this frequency modification by considering a detuning mechanism due to the slowdown of the background flow. By introducing a semi-analytical model, we show that the departure of the flow from the solid body rotation leads to a modification of the dispersion relation of Kelvin modes and to a detuning of the resonance condition. Our calculations reproduce the features of experimental measurements. We also show that a second frequency set, including one very low frequency as observed in the experiment, does not exhibit the properties of a parametric resonance between Kelvin modes. Our observations suggest that it may correspond to the instability of a geostrophic mode.
description: 26 pages, 17 figures, accepted by Phys. Rev. Fluids
Additional file 5 of Hospital contextual factors affecting the implementation of health technologies: a systematic review
Creators: name: Grossi, Adriano
name: Hoxhaj, Ilda
name: Gabutti, Irene
name: Specchia, Maria Lucia
name: Cicchetti, Americo
name: Boccia, Stefania
name: de Waure, Chiara
Publisher: name: figshare
Year: 2021
Subjects: Space Science
Medicine
Cancer
Science Policy

description: Additional file 5.
Ultracold atoms in optical lattices generated by quantized light fields
Creators: name: Maschler, Christoph
name: Mekhov, Igor B.
name: Ritsch, Helmut
Publisher: name: arXiv
Year: 2007
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study an ultracold gas of neutral atoms subject to the periodic optical potential generated by a high-$Q$ cavity mode. In the limit of very low temperatures, cavity field and atomic dynamics require a quantum description. Starting from a cavity QED single atom Hamiltonian we use different routes to derive approximative multiparticle Hamiltonians in Bose-Hubbard form with rescaled or even dynamical parameters. In the limit of large enough cavity damping the different models agree. Compared to free space optical lattices, quantum uncertainties of the potential and the possibility of atom-field entanglement lead to modified phase transition characteristics, the appearance of new phases or even quantum superpositions of different phases. Using a corresponding effective master equation, which can be numerically solved for few particles, we can study time evolution including dissipation. As an example we exhibit the microscopic processes behind the transition dynamics from a Mott insulator like state to a self-ordered superradiant state of the atoms, which appears as steady state for transverse atomic pumping.
description: 17 pages, 10 figures, Published version
PSYCHOMETRIC ANALYSIS OF NOISE POLLUTION ON TRAFFIC WARDENS IN THE DISTRICT OF SOUTH KARACHI
Creators: name: SHAFEIN JATOI
name: ALI BORICHA
name: MUHAMMAD AIJAZ
name: MUHAMMAD SHAHBAZ
name: MUHAMMAD AAMASH
name: MUHAMMAD AHMED BUTT
name: ALI MUNTAZIR NAQVI
Publisher: name: Zenodo
Year: 2024
Subjects: Depression, Professional Hazard, Mental Health.

description: Abstract

Objective: To analyze psychological changes such as stress, anxiety and depression in exposed and non-exposed traffic police Place and duration of the study: The experimental study was designed at Al-Tibri Medical College and Hospital, during Jan 2023 to Mar 2023 Material and Methods: Total 150 traffic wardens of different sites of Karachi south, Sindh Pakistan recruited in the survey. Survey was conducted thorough personal interviews and based on becky henry depression inventory scale online google form. Data was statistically analyzed by SPSS and Chi-square was performed to analyze the relationship between the professional environment and mental health. Results: The study reports the findings of an investigation into the physical and mental health of traffic wardens. The mean age of the recruited wardens was 38.72 ± 12.19 years, and the average exposure time throughout their service was 6.24 ± 5.39 years. The mean noise level during sampling was recorded at 77.17 ± 9.89 decibels. The study found high levels of depression (58%), anxiety (64.7%), and stress (70.7%) among the participants. There was a statistically significant association between depression and exposure to noise (p-value 0.001), while anxiety and stress did not show any significant association (p-value 0.036 and 0.166, respectively). Conclusion: The study highlights the alarming levels of depression, anxiety, and stress among traffic wardens. The findings indicate a significant association between depression and exposure to noise, which could have serious implications for the physical and mental well-being of traffic wardens.
title: Empowering Leadership: A Participatory Inquiry into Enhancing Leader Self-Efficacy at M.O.S.A.I.C
Creators: name: Koch, Laurie
Publisher: name: Vancouver Island University
Year: 2024
Subjects: School of leadership studies

description: 2024
description: This thesis focuses on the perspectives of coordinators and managers within an immigrant and refugee settlement organization named M.O.S.A.I.C. (Multi-lingual Orientation Service Association for Immigrant Communities), aiming to understand their suggestions for enhancing leader self-efficacy (LSE). Working with the methodology of action research, this study employed PhotoVoice interviews, focus groups, and an anonymous survey to inform the development of recommendations. The study adhered to established ethical principles, including those outlined by Royal Roads University, guiding the entire research process. This study investigates strategies to enhance leader self-efficacy (LSE) among coordinators and managers within M.O.S.A.I.C. Participants in the focus groups, PhotoVoice sessions, and surveys articulated twenty-five recommendations that coalesce around four overarching themes to enhance LSE at M.O.S.A.I.C. Theme 1 focuses on the need for tailored leadership training, including personalized growth plans and specialized programs addressing self-efficacy needs. Theme 2 emphasizes the importance of internal support and resources, advocating for increased financial allocations, streamlined processes, and community-building initiatives. Communication and collaboration, explored in Theme 3, highlight the significance of open dialogue, transparent communication channels, and technological enhancements. Finally, Theme 4 examines organizational culture and values, urging the promotion of inclusion, environmental responsibility, and a positive leadership culture. These findings provide a roadmap for fostering LSE, encouraging collaboration, and nurturing a supportive organizational environment within M.O.S.A.I.C. Keywords: Leadership effectiveness, leader self-efficacy, action research, M.O.S.A.I.C., organizational development, not-for-profit.
Equine Methicillin-Resistant Sequence Type 398 Staphylococcus aureus (MRSA) Harbor Mobile Genetic Elements Promoting Host Adaptation
Creators: name: Walther, Birgit
name: Klein, Katja-Sophia
name: Barton, Ann Kristin
name: Semmler, Torsten
name: Huber, Charlotte
name: Merle, Roswitha
name: Tedin, Karsten
name: Mitrach, Franziska
name: Lübke-Becker, Antina
name: Gehlen, Heidrun
Publisher: name: Freie Universität Berlin
Year: 2018
Subjects: subject: MRSA
subject: multi-drug resistance
subject: horses
subject: one health
subject: host range
subject: ST398
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::636 Viehwirtschaft

description: Continuing introduction of multi-drug resistant, zoonotic pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) in horse clinics challenges the biosafety of employees and animal patients. This study was aimed to determine the occurrence of mobile genetic elements facilitating survival in the early stages of invasive infection in different host species, including humans and horses, in MRSA carried by equine patients admitted to a large horse clinic. A total of 341 equine patients were investigated for carriage of MRSA by hygiene screening directly at hospital admission. MRSA were further investigated by antimicrobial susceptibility testing, whole-genome sequencing and genomic composition, including virulence factors involved in immune evasion and host adaption. From a total of 340 validated specimens from equine nostrils, 3.5% yielded positive results for MRSA. All MRSA were found to be closely related belonging to sequence type (ST) 398_t011 with up to four additional antimicrobial resistances. All MRSA harbored a specific Staphylococcal Pathogenicity Island (SaPIbov5) involved in facilitating survival in ruminant and equine plasma. Moreover, a β-hemolysin (hlb) converting ΦSa3 phage encoding the human-specific Immune Evasion Cluster (IEC) was present in 72% of the isolates. An equid-specific leukotoxin encoded by a further temperate phage (Saeq1) was only rarely detected (22%). Despite the absence of β-hemolysin production for all IEC-positive ST398, a prominent hemolysis zone was demonstrable on sheep blood agar. Thus, IEC might remain undetected among the ST398 lineage, since the presence of IEC is commonly associated with reduction of hemolysis in S. aureus belonging to other genetic backgrounds. Here we describe MRSA-ST398 harboring different mobile genetic elements encoding variants of immune evasion factors and toxins previously shown to contribute to S. aureus invasive diseases in specific host species or ecologic niches. We suggest these combinations contribute to the adaptation of MRSA belonging to ST398 with respect to epidemic spread across different habitats and hosts, and may therefore confer a host “generalist” phenotype.
Sparse Travel Time Estimation from Streaming Data
Creators: name: Jabari, Saif Eddin
name: Freris, Nikolaos M.
name: Dilip, Deepthi Mary
Publisher: name: arXiv
Year: 2018
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We address two shortcomings in online travel time estimation methods for congested urban traffic. The first shortcoming is related to the determination of the number of mixture modes, which can change dynamically, within day and from day to day. The second shortcoming is the wide-spread use of Gaussian probability densities as mixture components. Gaussian densities fail to capture the positive skew in travel time distributions and, consequently, large numbers of mixture components are needed for reasonable fitting accuracy when applied as mixture components. They also assign positive probabilities to negative travel times. To address these issues, this paper derives a mixture distribution with Gamma component densities, which are asymmetric and supported on the positive numbers. We use sparse estimation techniques to ensure parsimonious models and propose a generalization of Gamma mixture densities using Mittag-Leffler functions, which provides enhanced fitting flexibility and improved parsimony. In order to accommodate within-day variability and allow for online implementation of the proposed methodology (i.e., fast computations on streaming travel time data), we introduce a recursive algorithm which efficiently updates the fitted distribution whenever new data become available. Experimental results using real-world travel time data illustrate the efficacy of the proposed methods.
title: The Infamous “Titanic” Law and the Key Bridge Collapse
Creators: name: Patel, Mahi
Publisher: name: United States International Trade Commission
publisherIdentifier: https://ror.org/05hsggr76
publisherIdentifierScheme: ROR
Year: 2025

description: On March 26, 2024, the Dali, a nearly 1,000-foot-long container ship weighing 95,000 tons, lost power and
collided with the Francis Scott Key Bridge in Baltimore, Maryland. The collision resulted in loss of life for six
construction workers, as well as disruptions to many supply chains, economic loss to the Baltimore region,
a loss of a major transportation access to the Port of Baltimore, and increased car traffic congestion.
Following the disaster, the state of Maryland, the U.S. Department of Justice, and the victims’ families filed
lawsuits against the Dali owner (Grace Ocean Private Ltd.). This EBOT explains a long-standing maritime
law that has been invoked by the Dali’s owner to limit its liability for losses related to the accident
Effective temperatures of magnetic CP stars from full spectral energy distributions
Creators: name: Lipski, L.
name: Stepien, K.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: New determinations of effective temperatures of 23 magnetic, chemically peculiar (mCP) stars were obtained from a fit of metal enhanced model atmospheres to the observed spectral energy distributions (SED) from UV to red. The root-mean-square (RMS) method was used to fit the theoretical SED to the observations corrected for reddening if necessary, with metallicity and effective temperature as the fitting parameters. Gravity was assumed to be equal to log g = 4 for main sequence stars and to log g = 3 for two giants in the considered sample. Equal weights were given to the UV part and visual part of SED. Independently of the formal quality of fit resulting from the RMS method applied to the whole SED, the quality of fit was additionally checked for each star by determination of the temperature from the best fitting model atmosphere to the UV part and the visual part of SED separately. Both temperatures should be close to one another if the global best fitting model satisfactorily describes the full observed SED. This is the case for about a half of the investigated stars but the difference exceeds 750 K for the remaining stars with the extreme values above 2000 K. Possible reasons for such discrepancies are discussed. New, revised calibrations of effective temperature and bolometric corrections of mCP stars in terms of reddening free Stromgren indices are given.
description: 13 pages, 5 figures, accepted to MNRAS
Machine Learning in Healthcare: towards Data Structure and Causality
Creators: name: Liu, Zheng
Publisher: name: University of Illinois at Chicago
Year: 2024

description: To enhance the quality of medical services, Machine Learning (ML) techniques have been widely applied to model Electronic Health Records (EHRs). Nevertheless, clinical data present two significant challenges: data heterogeneity and complex causality, preventing the further application of ML models. The first challenge comes from the complexity of data structure. EHRs may consist of information from various sources presented in an unstructured format. To address this issue, one viable approach is to transform the raw EHR data into knowledge graphs (KGs) and utilize Graph Neural Networks (GNNs). However, given the imbalanced distribution and inherent heterogeneity of EHR data, the need for more robust GNNs tailored to the specifics of EHRs becomes imperative. In this thesis, we introduce two of my models, HSGNN and MHDP, custom-designed to handle specific EHR data and tackle this challenge.
The second challenge is rooted in the intricate latent structure of EHRs and the potential for algorithmic bias. Given the high cost associated with collecting EHR data, there may be inherent selection bias and a missing-not-at-random nature in EHRs. This can further cause algorithmic bias on ML models, especially when data volume is low. Furthermore, as demo- graphics in EHRs often act as confounders, deep learning models may exhibit confounding bias when working with observational data. To tackle these issues, we embrace causal inference theories, including using a deconfounder, to mitigate health disparities and enhance the gen- eralization capabilities of our models. In this paper, we introduce two of my models, PriMeD and FLMD, to achieve fairer predictions and more generalizable models.
Robustness Testing of the Microsoft Win32 API
Creators: name: Shelton, Charles
name: Koopman, Philip
name: Kobey  DeVale
Publisher: name: Carnegie Mellon University
Year: 2000
Subjects: subject: 80399 Computer Software not elsewhere classified
subject: FOS: Computer and information sciences

description: Although Microsoft Windows is being deployed in mission-critical applications, little quantitative data has been published about its robustness. We present the results of executing over two million Ballista-generated exception handling tests across 237 functions and system calls involving six Windows variants, as well as similar tests conducted on the Linux operating system. Windows 95, Windows 98, and Windows CE were found to be vulnerable to complete system crashes caused by very simple C programs for several different functions. No system crashes were observed on Windows NT, Windows 2000, and Linux. Linux was significantly more graceful at handling exceptions from system calls in a program-recoverable manner than Windows NT and Windows 2000, but those Windows variants were more robust than Linux (with glibc) at handling C library exceptions. While the choice of operating systems cannot be made solely on the basis of one set of tests, it is hoped that such results will form a starting point for comparing dependability across heterogeneous platforms.
Additional file 6 of Hospital contextual factors affecting the implementation of health technologies: a systematic review
Creators: name: Grossi, Adriano
name: Hoxhaj, Ilda
name: Gabutti, Irene
name: Specchia, Maria Lucia
name: Cicchetti, Americo
name: Boccia, Stefania
name: de Waure, Chiara
Publisher: name: figshare
Year: 2021
Subjects: Space Science
Medicine
Cancer
Science Policy

description: Additional file 6.
The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation
Creators: name: Vogel, Alexander
name: Bosse, Mathias
name: Gauglitz, Marcel
name: Wistuba, Sarah
name: Schmidt, Peter
name: Kaiser, Anette
name: Gurevich, Vsevolod V.
name: Beck-Sickinger, Annette G.
name: Hildebrand, Peter W.
name: Huster, Daniel
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: GPCR
subject: arrestin
subject: molecular switch
subject: NMR spectroscopy
subject: structural dynamics
subject: MD simulation
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: We report data on the structural dynamics of the neuropeptide Y (NPY) G-protein-coupled receptor (GPCR) type 1 (Y1R), a typical representative of class A peptide ligand GPCRs, using a combination of solid-state NMR and molecular dynamics (MD) simulation. First, the equilibrium dynamics of Y1R were studied using 15N-NMR and quantitative determination of 1H-13C order parameters through the measurement of dipolar couplings in separated-local-field NMR experiments. Order parameters reporting the amplitudes of the molecular motions of the C-H bond vectors of Y1R in DMPC membranes are 0.57 for the Cα sites and lower in the side chains (0.37 for the CH2 and 0.18 for the CH3 groups). Different NMR excitation schemes identify relatively rigid and also dynamic segments of the molecule. In monounsaturated membranes composed of longer lipid chains, Y1R is more rigid, attributed to a higher hydrophobic thickness of the lipid membrane. The presence of an antagonist or NPY has little influence on the amplitude of motions, whereas the addition of agonist and arrestin led to a pronounced rigidization. To investigate Y1R dynamics with site resolution, we conducted extensive all-atom MD simulations of the apo and antagonist-bound state. In each state, three replicas with a length of 20 μs (with one exception, where the trajectory length was 10 μs) were conducted. In these simulations, order parameters of each residue were determined and showed high values in the transmembrane helices, whereas the loops and termini exhibit much lower order. The extracellular helix segments undergo larger amplitude motions than their intracellular counterparts, whereas the opposite is observed for the loops, Helix 8, and termini. Only minor differences in order were observed between the apo and antagonist-bound state, whereas the time scale of the motions is shorter for the apo state. Although these relatively fast motions occurring with correlation times of ns up to a few µs have no direct relevance for receptor activation, it is believed that they represent the prerequisite for larger conformational transitions in proteins.
title: Oxidative Stress Causes Consequences and the Role of Phyto medicine  in Modern Prospects
title: Oxidative Stress Causes Consequences and the Role of Phyto medicine  in Modern Prospects
titleType: Other
Creators: name: Pandey, Abhishek kumar
Publisher: name: Indian Journal of Natural Sciences
Year: 2024

description: In a living system lots of biochemical reactions are running which simultaneously may generate various free radicals and reactive oxygen species. Their elimination must be required for the survival of the organism. For the accomplishment of this task the body has its antioxidant mechanism but it may collapse when free radicals are generated in huge amounts. The higher concentration of ROS and freeradicals may lead to disturbance in physiology ultimately leading to a pathological condition. The present review describes the cause, and impact of oxidative stress in the body. In the modern age due to the limitation of synthetic drugs, researchers are centric on to use of medicinal plants to avoid oxidative stress in normal conditions as well as in pathological conditions. Plants possess various phytoconstituents which may have a therapeutic effect on the body. These phyto constituents are also considered phyto medicine because of possess medicinal activity. There view also focuses on phytomedicine’s use to get rid of oxidative stress
description: In a living system lots of biochemical reactions are running which simultaneously may generate various free radicals and reactive oxygen species. Their elimination must be required for the survival of the organism. For the accomplishment of this task the body has its antioxidant mechanism but it may collapse when free radicals are generated in huge amounts. The higher concentration of ROS and freeradicals may lead to disturbance in physiology ultimately leading to a pathological condition. The present review describes the cause, and impact of oxidative stress in the body. In the modern age due to the limitation of synthetic drugs, researchers are centric on to use of medicinal plants to avoid oxidative stress in normal conditions as well as in pathological conditions. Plants possess various phytoconstituents which may have a therapeutic effect on the body. These phyto constituents are also considered phyto medicine because of possess medicinal activity. There view also focuses on phytomedicine’s use to get rid of oxidative stress
Additional file 1 of Resilience and pain catastrophizing among patients with total knee arthroplasty: a cohort study to examine psychological constructs as predictors of post-operative outcomes
Creators: name: Nwankwo, Vesta C.
name: Jiranek, William A.
name: Green, Cynthia L.
name: Allen, Kelli D.
name: George, Steven Z.
name: Bettger, Janet Prvu
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biotechnology
Science Policy

description: Additional file 1. Supplemental Table 1. Patient-Reported Outcome Measure Scores at 3-Months Postoperative and Change from Baseline in Study Population.
Time Scaling of Chaotic Systems: Application to Secure Communications
Creators: name: Materassi, Donatello
name: Basso, Michele
Publisher: name: arXiv
Year: 2007
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: The paper deals with time-scaling transformations of dynamical systems. Such scaling functions operate a change of coordinates on the time axis of the system trajectories preserving its phase portrait. Exploiting this property, a chaos encryption technique to transmit a binary signal through an analog channel is proposed. The scheme is based on a suitable time-scaling function which plays the role of a private key. The encoded transmitted signal is proved to resist known decryption attacks offering a secure and reliable communication.
description: 15 pages, 7 figures
Additional file 2 of Resilience and pain catastrophizing among patients with total knee arthroplasty: a cohort study to examine psychological constructs as predictors of post-operative outcomes
Creators: name: Nwankwo, Vesta C.
name: Jiranek, William A.
name: Green, Cynthia L.
name: Allen, Kelli D.
name: George, Steven Z.
name: Bettger, Janet Prvu
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biotechnology
Science Policy

description: Additional file 2. Supplemental Table 2. Unadjusted and Adjusted Models for KOOS IS at 3-Months Postoperative.
Do Only White or Asian Males Belong in Genius Organizations? How Academic Organizations’ Fixed Theories of Excellence Help or Hinder Different Student Groups’ Sense of Belonging
Creators: name: Bauer, Christina Anna
name: Hannover, Bettina
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: stereotypes
subject: organizational implicit theories
subject: gender
subject: ethnicity
subject: belonging
subject: prototype
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: High-profile organizations often emphasize fixed giftedness rather than malleable effort-based criteria as critical for excellent achievements. With giftedness being primarily associated with White or Asian males, such organizational implicit theories of excellence may shape individuals’ sense of belonging depending on the extent to which they match the gifted White/Asian male prototype, i.e., the prototypical gifted person which is typically imagined to be a White or Asian male. Previous research has reported fixed excellence theories emphasizing giftedness (vs. malleable theories emphasizing effort) to impair the sense of belonging of females and negatively stereotyped ethnic minorities. We investigate the combined effects of gender and ethnicity. We predicted that, while individuals whose gender and ethnicity do not match the gifted prototype show a reduced sense of belonging in fixed organizations, White/Asian males who match the gifted prototype show the opposite effect, experiencing a higher sense of belonging in fixed (vs. malleable) organizations. In an experimental study (N = 663 students), we manipulated advertising material used by a highly selective academic institution in Germany and tested effects on students’ belonging. Whereas the original material emphasized giftedness as essential for excelling (fixed excellence version), our manipulated version stressed effort (malleable version). As expected, females from stereotyped ethnic minority groups felt less belonging in the fixed (vs. malleable) organization, while White/Asian males anticipated stronger belonging in the fixed (vs. malleable) organization. Fixed views of excellence impair negatively stereotyped individuals’ belonging but may even strengthen the belonging of prototypical academic elites.
Robustness Testing of A Distributed Simulation Backplane
Creators: name: Fernsler, Kimberly
name: Koopman, Philip
Publisher: name: Carnegie Mellon University
Year: 1999
Subjects: subject: 80399 Computer Software not elsewhere classified
subject: FOS: Computer and information sciences

description: Creating robust software requires not only careful specification and implementation, but also quantitative measurement. This paper describes Ballista exception handling testing of the High Level Architecture Run-Time Infrastructure (HLA RTI). The RTI is a standard distributed simulation system intended to provide completely robust exception handling, yet implementations have normalized robustness failure rates as high as 10%. Non-robust testing responses include exception handler crashes, segmentation violations, "unknown" exceptions, and task hangs. Other issues include different robustness failure modes across ports to two operating systems, and mandatory client machine rebooting after a particular RTI failure. Testing the RTI led to scalable extensions of the Ballista architecture for handling exception-based error reporting models, testing object-oriented software structures (including call-backs, pass by reference, and constructors), and operating in a state-rich, distributed system environment. These results demonstrate that robustness testing can provide useful feedback to high-quality software development processes, and can be applied to domains well beyond the previous work on testing operating systems.
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 401
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 401, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 401, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
New physics vs new paradigms: distinguishing CPT violation from NSI
Creators: name: Barenboim, Gabriela
name: Ternes, Christoph Andreas
name: Tórtola, Mariam
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Our way of describing Nature is based on local relativistic quantum field theories, and then CPT symmetry, a natural consequence of Lorentz invariance, locality and hermiticity of the Hamiltonian, is one of the few if not the only prediction that all of them share. Therefore, testing CPT invariance does not test a particular model but the whole paradigm. Current and future long baseline experiments will assess the status of CPT in the neutrino sector at an unprecedented level and thus its distinction from similar experimental signatures arising from non-standard interactions is imperative. Whether the whole paradigm is at stake or just the standard model of neutrinos crucially depends on that.
description: version 2, matches published version
A metal-line strength indicator for Damped Lyman Alpha (DLA) systems at low signal-to-noise
Creators: name: Arinyo-i-Prats, Andreu
name: Mas-Ribas, Lluis
name: Miralda-Escude, Jordi
name: Perez-Rafols, Ignasi
name: Noterdaeme, Pasquier
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The Baryon Oscillation Spectroscopic Survey of SDSS-III has provided an unprecedentedly large sample of Damped \lya systems (DLAs), the largest repositories of neutral hydrogen in the Universe. This DLA sample has been used to determine the DLA bias factor from their cross-correlation with the \lya forest absorption in \cite{FontRibera2012,Perez2018}, showing that DLAs are associated with relatively massive halos. However, the low resolution and signal-to-noise of BOSS spectra do not allow precise measurements of the DLA metal lines. We define a metal strength parameter, $S$, based on combining equivalent widths of 17 metal lines, that can be measured with an optimal signal-to-noise ratio for individual DLAs in BOSS spectra, allowing for the classification of the DLA population into subgroups of different $S$. We present the distribution of this DLA metal strength and the dependence of its mean value on $N_{\rm HI}$ and redshift. We search for systematic effects and variations in the catalogue purity by examining the dependence of the $S$ distribution on the spectral signal-to-noise and the estimated error on $S$. A catalogue of DLAs with measured equivalent widths for the selected 17 metal lines and the value of $S$ is made publicly available, which will be used to measure the dependence of the DLA bias factor on the $S$ parameter. The relation of the metal strength on the gas metal abundances and velocity dispersion can be constrained by studying the stacked metal absorption spectra of DLAs as a function of $S$, allowing for future determinations of the dependence of the bias factor on the metallicity and velocity dispersion of DLAs.
description: 12 pages, 10 figures, link to online catalogue (https://github.com/andreuandreu/Catalogue_Metal_Strength_DLAs_SDSS-BOSS_DR12)
A policy iteration algorithm for nonzero-sum stochastic impulse games
Creators: name: Aïd, René
name: Bernal, Francisco
name: Mnif, Mohamed
name: Zabaljauregui, Diego
name: Zubelli, Jorge P.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Optimization and Control (math.OC)
subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: This work presents a novel policy iteration algorithm to tackle nonzero-sum stochastic impulse games arising naturally in many applications. Despite the obvious impact of solving such problems, there are no suitable numerical methods available, to the best of our knowledge. Our method relies on the recently introduced characterization of the value functions and Nash equilibrium via a system of quasi-variational inequalities. While our algorithm is heuristic and we do not provide a convergence analysis, numerical tests show that it performs convincingly in a wide range of situations, including the only analytically solvable example available in the literature at the time of writing.
description: Floats positions corrected. 23 pages, 8 figures
Extending Bell inequalities to more parties
Creators: name: Wu, Yu-Chun
name: Badziag, Piotr
name: Wieśniak, Marcin
name: Żukowski, Marek
Publisher: name: arXiv
Year: 2007
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We describe a method of extending Bell inequalities from $n$ to $n+1$ parties and formulate sufficient conditions for our method to produce tight inequalities from tight inequalities. The method is non trivial in the sense that the inequalities produced by it, when applied to entangled quantum states may be violated stronger than the original inequalities. In other words, the method is capable of generating inequalities which are more powerfull indicators of non-classical correlations than the original inequalities.
description: 8 pages, no figure
Synthesis of FASN-Specific Novel PET Tracers for Improved Prostate Cancer Diagnosis
Creators: name: Ortiz Torres, Desire
Publisher: name: University of Illinois at Chicago
Year: 2024

description: Prostate cancer is projected to account for nearly 29% of all cancer diagnoses in the U.S. in 2023, with an estimated 288,300 new cases and 34,700 fatalities, underscoring its position as leading cancer among men. While strides have been made in early detection, the prevalent risk assessment methods, including clinical T-stage, PSA count, and the Gleason score, often fall short in distinguishing between the disease's indolent and aggressive form. Consequently, there is a growing demand for innovative biomarkers to refine prognosis assessments and therapeutic monitoring by accurately characterizing cancer phenotypes. A promising candidate is the lipogenic enzyme, Fatty acid synthase (FASN; E.C.2.3.1.85), due to its central role in the lipogenesis and tumor cell proliferation (Warburg effect), along with its varied expression levels between tumors and normal tissue. The potential to image its activity using radiolabeled molecules opens new doors for tumor assessment and therapeutic strategy formulation. Positron emission tomography (PET) stands out as a significant, non-invasive technique to visualize cancer traits in vivo. This dissertation centers on: (1) a comprehensive review of early-stage prostate cancer diagnosis, and (2) crafting PET tracers for in vivo FASN imaging, with the goal of advancing the predictive and pharmacodynamic understanding of prostate cancer. Inspired by two potent classes of FASN inhibitors, GSK-class and TVB-class, several new probes were synthesized, and their biological performance evaluated.
title: Εφαρμογή Android για ιδιωτική αλληλεπίδραση με LLMs σε τοπικό περιβάλλον
title: Android application for private interaction LLMs in a local environment
titleType: AlternativeTitle
Creators: name: Κοξάνογλου, Θεόδωρος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2024
Subjects: subject: Εφαρμογή android
subject: Προσωπικός βοηθός
subject: Ιδιωτικότητα
subject: Τοπική λύση
subject: Μεγάλα γλωσσικά μοντέλα
subject: Android application
subject: Personal assistant
subject: Privacy
subject: Local solution
subject: Large language models

description: Η παρούσα πτυχιακή εργασία επικεντρώνεται στην ανάπτυξη μιας εφαρμογής που επιτρέπει στον χρήστη να αλληλεπιδρά με «Μεγάλα Γλωσσικά Μοντέλα» (LLMs) χωρίς τη χρήση υπηρεσιών νέφους, προσφέροντας μεγαλύτερη ασφάλεια και έλεγχο στα δεδομένα του. Η εφαρμογή «Home AI» αξιοποιεί πόρους από τον τοπικό υπολογιστή του χρήστη, προσφέροντας εξατομικευμένες απαντήσεις. Οι κύριοι στόχοι της εφαρμογής περιλαμβάνουν την ιδιωτικότητα των δεδομένων μέσω τοπικής επεξεργασίας, την εξατομίκευση των απαντήσεων με βάση τα δεδομένα του χρήστη, τη δημιουργία φιλικού περιβάλλοντος και την αξιοποίηση τοπικών πόρων για την εξάλειψη της ανάγκης εξωτερικών υπηρεσιών. Για την επίτευξη αυτών των στόχων, σχεδιάστηκε ένα σύστημα αρχιτεκτονικής client-server, προσφέροντας μια ασφαλή εμπειρία χρήστη. Ο server βασίζεται στον «Έλεγχο Πρόσβασης Βασισμένο σε Ρόλους» (RBAC) και υλοποιήθηκε με σύγχρονες τεχνολογίες, όπως FastAPI, ασφάλεια με JWT, Postgres, ChromaDB και Ollama για αλληλεπίδραση με LLMs. Ο client είναι μια Android εφαρμογή που επιτρέπει την αλληλεπίδραση με τον server μέσω μιας φιλικής και λειτουργικής «Διεπαφής Χρήστη» (UI). Η ανάπτυξη βασίστηκε σε «Καθαρή Αρχιτεκτονική» (Clean Architecture), με τεχνολογίες όπως Retrofit, OkHttp, Jetpack Compose και Kotlin Coroutines, προσφέροντας ευέλικτη εμπειρία χρήσης.
Robustness Testing and Hardening of CORBA ORB Implementations
Creators: name: Jiantao  Pan
name: Koopman, Philip
name: Siewiorek, Daniel
name: Yennun  Huang
name: Gruber, Robert
name: Jiang, Mimi Ling
Publisher: name: Carnegie Mellon University
Year: 2001
Subjects: subject: 80399 Computer Software not elsewhere classified
subject: FOS: Computer and information sciences

description: Before using CORBA (Common Object Request Broker Architecture) applications in mission-critical scenarios, it is important to understand the robustness of the Object Request Broker (ORB) being used, which forms the platform for CORBA applications. We have extended the Ballista software testing technique to test the exception-handling robustness of C++ ORB client-side application interfaces, and have tested two major versions of three ORB implementations on two operating systems, yielding robustness failure rates ranging from 26% to 42%. To improve ORB robustness, we also propose a probing method to harden object and pseudo-object related data types against exceptional inputs. Using these probes on omniORB 2.8 has proven to be effective in eliminating some cases of robustness failures found during testing. These results suggest that CORBA implementations currently have significant robustness vulnerabilities, but that some important classes of problems can be overcome with better exception-handling approaches.
Robust Software – No More Excuses
Creators: name: DeVale, John
name: Koopman, Philip
Publisher: name: Carnegie Mellon University
Year: 2002
Subjects: subject: 80399 Computer Software not elsewhere classified
subject: FOS: Computer and information sciences

description: Software developers identify two main reasons why software systems are not made robust: performance and practicality. This work demonstrates the effectiveness of general techniques to improve robustness that are practical and yield high performance. We present data from treating three systems to improve robustness by a factor of 5 or more, with a measured performance penalty of under 5% in nearly every case, and usually under 2%. We identify a third possible reason why software systems are not made robust: developer awareness. A case study on three professional development groups evaluated their ability to estimate the robustness of their software. Two groups were able to estimate their software’s robustness to some extent, while one group had more divergent results. Although we can overcome the technical challenges, it appears that even experienced developers can benefit from tools to locate robustness failures and training in robustness issues.
Additional file 3 of Resilience and pain catastrophizing among patients with total knee arthroplasty: a cohort study to examine psychological constructs as predictors of post-operative outcomes
Creators: name: Nwankwo, Vesta C.
name: Jiranek, William A.
name: Green, Cynthia L.
name: Allen, Kelli D.
name: George, Steven Z.
name: Bettger, Janet Prvu
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Biotechnology
Science Policy

description: Additional file 3. Supplemental Table 3. Unadjusted and Adjusted Models for PROMIS PH at 3-Months Postoperative.
Exploring the chiral regime with dynamical overlap fermions
Creators: name: Matsufuru, Hideo
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: I report the status of the dynamical overlap fermion project by the JLQCD and TWQCD collaborations. So far, the simulations have been completed with two flavors of overlap sea quarks in a wide range of sea quark mass corresponding the $p$-regime and the $ε$-regime on a $16^3\times 32$ lattice at $a=$0.12 fm. More recently, runs with 2+1 flavors of sea quarks have also started. This talk mainly discusses the physics results on the $N_f=2$ lattice after describing the lattice formulation and algorithms.
description: 15 pages, 14 figures, contribution to 25th International Symposium on Lattice Field Theory, Regensburg, Germany, 30 Jul - 4 Aug 2007