cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Isotomiella minor
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Isotomiella
Isotomiella minor

description: Isotomiella minor (Schäffer, 1896)
– Isotoma minor Schäffer, 1896: 182.
MAZ: Yahyapour 2012; Yoosefi Lafooraki 2014; Yoosefi Lafooraki & Shayanmehr 2014a; Mehrafrooz Mayvan et al. 2015a; Ghasemi Cherati 2017; Yoosefi Lafooraki et al. 2020b; GI: Cox 1982; Daghighi 2012; Daghighi et al. 2013a, b; Yoosefi Lafooraki et al. 2020b; EA: Cox 1982; NK: Mehrafrooz Mayvan et al. 2022a; TE: Moravvej et al. 2007; Qazi & Shayanmehr 2016b; GO: Hosseini et al. 2016a; Yoosefi Lafooraki et al. 2020b; KS: Ghahramaninezhad et al. 2013; Amiri & Kahrarian 2015; Arbea & Kahrarian 2015b; Kahrarian 2015; Kahrarian et al. 2016b; Kahrarian 2019; LO: Moradi et al. 2018, 2019; KE: Abdolalizadeh 2018; Abdolalizadeh et al. 2019, KU: Ahmadi 2021; Ahmadi et al. 2023.
Ecology and habitat in Iran: soil next to river, soil of lawn, leaf litter under oaks, plums and pines trees.
General distribution: Holarctic (Fjellberg 2007).
Genus Isotomodes Axelson, 1907
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 45, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
A novel agent to treat breast cancer brain metastases
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Fifty percent of patients with advanced hormone receptor negative breast cancer will develop brain metastases, including brain metastases that grow on the surface of the brain and nerves (leptomeningeal disease). As patients live longer, more patients develop brain metastases, and leptomeningeal disease is rapidly fatal. Cancer growing in the brain is particularly difficult to treat due to the blood-brain barrier blocking otherwise potent anti-cancer agents, and possible neurotoxicity from inadvertent effects of a treatment on normal brain cells. We have tested a novel agent that is actively transported into the brain, selectively kills breast cancer cells, and does not cross react with normal brain cells. This treatment has great potential to help patients with breast cancer brain metastases.
 We are one of only a few laboratories studying how breast cancer survives in the brain and how best to treat it. The novel drug we are testing uses a transporter the brain uses to import nutrients; this transporter is already used by other effective drugs to get into the brain. Breast cancer cells have many more of these transporters which they use in order to import more nutrients and grow faster. Our drug uses this increased number of transporters to selectively kill the tumor cells.
 Our preliminary tests show this new drug selectively kills breast cancer, is less toxic to normal brain cells than similar drugs, and improves survival in an aggressive animal model of breast cancer brain metastases. We will confirm this effect and test if the drug prevents implantation of breast cancer brain metastases in a mouse model. We will then determine the dose in humans for a Phase 2 clinical trial. We do this by giving an increasing amount of the drug to patients with small, asymptomatic breast-to-brain metastases. After receiving the drug for two cycles (about 8 weeks), patients will then get standard of care therapy (e.g. stereotactic radiosurgery) to their brain metastases. Our drug holds great promise for patients with breast cancer brain metastases including leptomeningeal disease, for whom no effective treatment currently exists. If successful, we will rapidly arrange for a multi-center Phase 1/2, NIH-supported clinical trial of our drug for the treatment and prevention of breast cancer brain metastases.
Hirticallia hirsuta Galileo & Martins 1990
Creators: name: Groll, Elisa Von
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Hirticallia
Hirticallia hirsuta

description: Hirticallia hirsuta Galileo & Martins, 1990
Galileo & Martins, 1990b:879, fig. 1.
Holotype ♀, BRAZIL, Rio Grande do Sul: Viamão (Itapuã), 19.I.1977, H. A. Gastal col. (MCNZ 27.779).
description: Published as part of Groll, Elisa Von, 2017, Catalogue of Coleoptera type specimens housed in the collection of the Museu de Ciências Naturais, Fundação Zoobotânica do Rio Grande do Sul, Brazil, pp. 439-473 in Zootaxa 4318 (3) on page 449, DOI: 10.11646/zootaxa.4318.3.2, http://zenodo.org/record/887750
Montetinea montana G. Petersen 1957
Creators: name: Bryner, Rudolf
name: Kopp, Andreas
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Tineidae
Montetinea
Montetinea montana

description: 698 Montetinea montana G. Petersen, 1957 – WA, SS
Kopp (2022): Entomo Helvetica 15: 136.
Neuer Nachweis: Trient (VS), FeYat, 1180 m ü.M., 563.8/102.1, 3.7.2021 (leg. R. BrYner).
description: Published as part of Bryner, Rudolf & Kopp, Andreas, 2023, Aktualisierung der Checkliste der Schmetterlinge (Lepidoptera) der Schweiz, pp. 39-60 in Entomo Helvetica 16 on page 42
Paracallia bonaldoi Martins & Galileo 1998
Creators: name: Groll, Elisa Von
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Paracallia
Paracallia bonaldoi

description: Paracallia bonaldoi Martins & Galileo, 1998
Martins & Galileo, 1998a:56, fig. 6.
Holotype ♂, BRAZIL, Acre: Xapuri, Pimenteira, 06.IV.1996 (MCNZ 234.784).
description: Published as part of Groll, Elisa Von, 2017, Catalogue of Coleoptera type specimens housed in the collection of the Museu de Ciências Naturais, Fundação Zoobotânica do Rio Grande do Sul, Brazil, pp. 439-473 in Zootaxa 4318 (3) on page 449, DOI: 10.11646/zootaxa.4318.3.2, http://zenodo.org/record/887750
Spätglaziale und holozäne Floren- und Vegetationsgeschichte des südlichen Mendelkamms, Südtirol (Provinz Bozen, Italien). Pollenanalytische Untersuchungen des Flachmoors Oberfennberg 1157 m ü. M.
Creators: name: Burga, Conradin A.
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Peat
subject: Pollen

description: Late-glacial and Holocene flora and vegetation history of the southern Mendel ridge, South Tyrol (Province of Bolzano, Italy). Palynological investigations of the peat bog Oberfennberg 1157 m a.s.l.

A peat bog section of 400–620 cm depth has been pollen analytically investigated. It comprises a period from ca. 15.600–ca. 5.480 cal yr BP, i. e., the end of the Oldest Dryas chronozone to the onset of the Subboreal chronozone. During the Late-glacial warm periods of the Bölling and Alleröd chronozones, the reafforestation started with pine (Pinus sylvestris/P. mugo) forest steppe with common birch (Betula pendula, possibly partly with B. nana), Artemisia, Juniperus, and Hippophaë. At the forest limit, Swiss stone pine (Pinus cembra) and European larch (Larix decidua) were probably present. Ephedra, Chenopodiaceae and Poaceae formed a rock steppe vegetation. During the Younger Dryas cold phase, a short recession of pine forest and a revival of steppe vegetation has been recognized. During the onset of the Holocene (Preboreal chronozone), pine forest reached its maximal range. At the transition Preboreal/Boreal, the coniferous forest vegetation changed basically after immigration of Norway spruce (Picea abies) in the montane belt and because of the spread of mixed oak forest (with Ostrya) in the colline belt. During the Boreal chronozone the maximum range of hazel (Corylus avellana), Scots pine/mountain pine (Pinus sylvestris/P. mugo) forest and mixed oak forests (with Ulmus, Quercus, Tilia, Acer, Fraxinus excelsior) recessed in advantage of the newly immigrated Norway spruce forests which reached its maximal range in the montane belt.

At the transition from the Boreal/Older Atlantic chronozone silver fir (Abies alba) and beech (Fagus sylvatica) immigrated. During the Older Atlantic, silver fir and Norway spruce forest dominated in the montane belt, whereas mixed oak forest declined, probably due to shade concurrence of silver fir and beech. Later, during Younger Atlantic, Scots pine/mountain pine, Swiss stone pine and European larch were again more abundant compared to Norway spruce, silver fir, beech and mixed oak forest, presumably because of a cooler Holocene climate oscillation. The youngest peat bog section, probably the onset of the Subboreal period, gives evidence of a montane silver fir-Norway spruce forest close to the peat bog zone (more stomata in the needles). At the forest limit Scots pine/mountain pine were growing with Swiss stone pine and European larch. The present montane beech-silver fir forest of Oberfennberg established later, during the younger Holocene.
Targeting FBXO44/SUV39H1 Silencing of LINE-1 Retrotransposons to Prevent Breast Cancer Recurrence
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Recurrence is a significant clinical challenge and major cause of breast cancer patient death. Unfortunately, there are currently no treatments that can effectively prevent breast tumor recurrences. Recently it was shown that a subtype of ancient virus called LINE-1 that is integrated in the DNA of cancer cells is essential for the generation of drug-resistant persisters, a small subpopulation of tumor cells that survives chemotherapy and initiates breast tumor recurrence. LINE-1 viruses have propagated in the human genome throughout evolution, composing nearly 25% of the genome. In preliminary studies, we found that a protein called FBXO44 and its enzymatic co-factor SUV39H1 prevents the expression of LINE-1 in breast cancer cells. Pharmacologic inhibition of SUV39H1 activated LINE-1 expression in breast cancer cells and stimulated cGAS-STING signaling, an antiviral pathway that promotes cellular senescence or apoptosis. Importantly, we found that FBXO44/SUV39H1 are not required in normal cells. Based on this data, we hypothesize that SUV39H1 inhibition could be a safe and effective therapeutic approach to prevent breast tumor recurrence by activating LINE-1 expression, thus eradicating drug-resistant cancer cells by activating cGAS-STING and inducing senescence/apoptosis. In this proposal we will determine the importance of cGAS-STING signaling in promoting the anti-breast tumor effects of FBXO44/SUV39H1 inhibition and perform preclinical studies to evaluate if SUV39H1 inhibition can prevent breast tumor recurrence. This research could identify a critically important regulatory pathway involved in breast tumor recurrence and validate SUV39H1 inhibitors as safe and effective treatments to prevent disease recurrence.
Pharmacological targeting of cholinergic receptors as a novel breast cancer immunotherapy
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The five-year survival rate of patients with metastatic breast cancer (MBC) is 27%, despite advances in diagnostics and treatment. Treatments based on immunotherapy have made substantial progress in some cancer types such as melanoma, but the success of immunotherapy has been limited in MBC. To address this unmet need, we have recently discovered a new biochemical target regulating immune cells in a mouse model of MBC that we can target with the drug, AR-R17779.

 AR-R17779 activates a receptor called CHRNA7 that is expressed on immune cells. Using mice that lack CHRNA7, we have shown that breast tumors grew larger, mice died sooner, and isolated breast tumor-associated immune cells were not activated. It is because of this observation that we hypothesized, and have now supported with a pilot study, that stimulating CHRNA7 with AR-R17779 activates the tumor resident immune cells and increased overall survival in a mouse model of MBC.

 We build upon our pilot study data with this drug to develop a research plan that will test the efficacy of AR-R17779 in two mouse models of MBC for a comprehensive understanding of the efficacy, dosing and timing on a preclinical model of MBC. In addition, we will define the effect of AR-R17779 on specific immune cells that mediate the reduction in tumor progression and increase in survival. Understanding AR-R17779-mediated changes in immune cells will allow us to personalize the treatment of patients with MBC on the basis of their immune response and genetic differences in their CHRNA7 pathway to identify those individuals that are most likely to respond to this drug.

 Previous studies in the field of neurosciences have demonstrated that AR-R17779 is highly specific and selective in the activation of CHRNA7 in models of schizophrenia in rodents. These studies are supported by partners with expertise in pharmacology and translating discoveries from academia to industry (Dr. Baird), clinical expertise in drug trials and patient care in MBC (Dr. Blair), and the input of Advocates to refine the scope of studies (Ms. Maues and Ms. Glenn). Together, our team and research design will help expedite the translation of AR-R17779 to the clinic should the studies proposed in this grant establish the effectiveness of AR-R17779 in fighting MBC.
Lower Raritan/Middlesex County 208 water quality management planning program; Analysis report: task 4.&, October 19&5 geometry survey
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1975

description: The objective of the geometry survey was primarily to provide crosssectional information on the surface -waterbodies for which lowflow, steady-state modeling was to be performed. Channel characteristic information was to be supplemented by velocity measurements and the visual observations. The survey was conducted in two parts: in the Raritan and South River estuaries and in the non-tidal waters.The report contains two chapters: 1. Program Outline and 2. Data Summary. The Program Outline chapter will include the rivers and estuaries covered in the survey and the methods of obtaining the data. The Data Summary chapter presents the milepoint system utilized for the study and the field data collected.
Paradrycothaea pilosicornis Galileo & Martins 2010
Creators: name: Groll, Elisa Von
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Paradrycothaea
Paradrycothaea pilosicornis

description: Paradrycothaea pilosicornis Galileo & Martins, 2010
Galileo & Martins, 2010:234, figs 1, 2.
Paratypes ♂, ♀, MÉXICO, Quintana Roo: Tulum (15–18 km N), 11–12.X.1982, J. E. Wappes col. (MCNZ 237.051, 237.052).
description: Published as part of Groll, Elisa Von, 2017, Catalogue of Coleoptera type specimens housed in the collection of the Museu de Ciências Naturais, Fundação Zoobotânica do Rio Grande do Sul, Brazil, pp. 439-473 in Zootaxa 4318 (3) on page 449, DOI: 10.11646/zootaxa.4318.3.2, http://zenodo.org/record/887750
Isotomodes golestani Yoosefi Lafooraki, Hajizadeh, Shayanmehr & Hosseini 2020
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Isotomodes
Isotomodes golestani

description: Isotomodes golestani Yoosefi Lafooraki, Hajizadeh, Shayanmehr & Hosseini, 2020
– Isotomodes golestani Yoosefi Lafooraki, Hajizadeh, Shayanmehr & Hosseini, 2020b: 548.
MAZ: Yoosefi Lafooraki et al. 2020b.
Ecology and habitat in Iran: soil.
General distribution: species known only from type locality (Yoosefi Lafooraki et al. 2020b).
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 45, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
Monopis neglecta Sumpich & Liska 2011
Creators: name: Bryner, Rudolf
name: Kopp, Andreas
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Tineidae
Monopis
Monopis neglecta

description: 711c Monopis neglecta Šumpich & Liška, 2011 – WA, SS
Gandria (TI), Trivelli, 410 m ü. M., 720/095, 10.5.2014, ein Weibchen beim Lichtfang an einem Südhang in einem Schluchtwald auf Kalkuntergrund (leg. & gen. det. D. Bolt). FullY (VS), Branson, 860 m ü. M., 572/112, 26.6.2020 (leg., gen. det. R. Bryner).
description: Published as part of Bryner, Rudolf & Kopp, Andreas, 2023, Aktualisierung der Checkliste der Schmetterlinge (Lepidoptera) der Schweiz, pp. 39-60 in Entomo Helvetica 16 on page 42
Middlesex County 208 area-wide waste treatment management planning; Task 8 - ground-water analysis, a. description of ground-water system, b. ground-water pollution sources
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1976

description: This report includes two major sections: a) description of the ground-water system and b) ground-water pollution sources, as well as selected references. Section A of this report presents a regional description of the ground-water system, including such factors as the patterns of replenishment, movement and discharge as they are effected by various natural factors and by pumping. These descriptions provide a detailed setting for the subsequent analyses which were undertaken in connection with the effects of various cultural practices on the quality of ground water.Section B discusses the major potential sources of ground-water pollution and analyzes them in terms of their impact on the quality of present and future ground-water supplies. It was determined that the most important pollution sources are: domestic on-site waste disposal, leaky sewers, liquid waste lagoons, landfills, faulty product storage and transmission facilities, road salts and certain agricultural practices.
Lower Raritan/Middlesex County 208 water quality management planning program; Task 4 report - 19&6 low flow survey
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1977

description: The report is organized to discuss the 19&6 low flow surveys under thefollowing headings:Chapter I - IntroductionChapter II - Program OutlineChapter III- DiscussionChapter IV - SummaryThe program outline chapter will describe the rivers and estuariessampled in the surveys, methods of obtaining the data, and analyticalmethods utilized in determining the parameter values. The datadiscussion chapter presents the data collected and a discussion of themajor parameters for each water body sampled. Comparisons with theNJDEP water quality standards and criteria are also made in thischapter. The 19&6 low flow surveys were conducted on three dates from late July to late August.
Additional file 2: of Transcriptomic study of Salmonella enterica subspecies enterica serovar Typhi biofilm
Creators: name: Khee Chian Jason Chin
name: Taylor, Todd
name: Hebrard, Maxime
name: Kogaan Anbalagan
name: Dashti, Marjan
name: Phua, Kia
Publisher: name: Figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified

description: Real time PCR (qPCR) was done on 8 selected genes, genes tatE, STY1254, STY0893, rmf, lppA, opmC, yjfO, and lex. The graphs in Figure S2 shows each gene and their real time PCR result based on relative fold change. Each gene’s relative fold change value reflects the log2-fold change result that was obtained using bioinformatics analysis. This validates the bioinformatics result as accurate. Figure S2. Relative fold-change in expression of the genes (A) tatE, (B) STY1254, (C) STY0893, (D) RMF, (E) lppA, (F) opmC, (G) yjfO, and (H) lexA of S. Typhi biofilm relative to planktonic cells. Statistics analysis (***P
Hands Off Tobacco and E-Cigarettes!: Tobacco & E-Cigarette Use Prevention for Deaf Youth
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Deaf and Hard-of-Hearing (Deaf/HH) youth are at risk for tobacco and e-cigarette use. Despite this risk, tobacco and e-cigarette use prevention programs that meet their unique need are not available in the same manner they are for hearing youth. For over twenty years, our research team has been working in partnership with Deaf educators and students to develop prevention programs that meet the needs of the Deaf community. With pilot funding from TRDRP, we recently updated our Hands Off Tobacco! program, the only tobacco use prevention education curriculum aimed at Deaf/HH youth, to include content on e-cigarettes and other emerging tobacco products. We now call the program, Hands Off Tobacco and E-Cigarettes! During our pilot work, teachers and students found the curriculum filled an important need for Deaf/HH youth in regards to tobacco and e-cigarette prevention. Teachers also provided valuable feedback on how the curriculum could be further refined to best meet the demands of sharing the content with Deaf/HH students in the classroom. They advocated for the development of more extensive signed, captioned, and voiced video content to augment the written curriculum.

 In order to further develop and test Hands Off Tobacco and E-Cigarettes! we aim to work with our community partners in the form of our Community Advisory Committee and Youth Champions to engage in the following activities: 1) update the current curriculum based on feedback we received during our pilot study; 2) develop extensive signed, captioned, and voiced video content to include in the curriculum; and 3) evaluate the program among Deaf/HH students who attend both Schools for the Deaf and mainstream programs. Upon completing our project, we will work with our community partners to share our curriculum with educators of Deaf/HH students throughout California and the nation.
A Preliminary Study of the Needs of Climate Data Users
Creators: name: Ravi, Savitha
name: Gauravarapu, Sai Krishna Ranjan
name: Coblenz, Michael
Publisher: name: Plateau Workshop
Year: 2024
Subjects: Programming Languages

description: The size of climate datasets has been rapidly expanding. As a result, climate scientists have evolving needs for data access, management, and analysis. This paper conducts a preliminary user study of four climate scientists to understand their current software development practices. We use our findings to suggest future work for designing better languages and tools for scientific computing in climate science.
Bucculatrix clavenae Klimesch 1950
Creators: name: Bryner, Rudolf
name: Kopp, Andreas
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Bucculatricidae
Bucculatrix
Bucculatrix clavenae

description: 1065a Bucculatrix clavenae Klimesch, 1950 – GR
Typenfundort u.a. Engadin (Klimesch 1950).
description: Published as part of Bryner, Rudolf & Kopp, Andreas, 2023, Aktualisierung der Checkliste der Schmetterlinge (Lepidoptera) der Schweiz, pp. 39-60 in Entomo Helvetica 16 on page 42
Schiacallia tristis Galileo & Martins 1991
Creators: name: Groll, Elisa Von
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Schiacallia
Schiacallia tristis

description: Schiacallia tristis Galileo & Martins, 1991
Galileo & Martins, 1991:248.
Paratype ♀, BRAZIL, Minas Gerais: Pedra Azul (700 m), 1972, Seabra & Oliveira col. (MCNZ 124.955).
description: Published as part of Groll, Elisa Von, 2017, Catalogue of Coleoptera type specimens housed in the collection of the Museu de Ciências Naturais, Fundação Zoobotânica do Rio Grande do Sul, Brazil, pp. 439-473 in Zootaxa 4318 (3) on page 450, DOI: 10.11646/zootaxa.4318.3.2, http://zenodo.org/record/887750
Lower Raritan Middlesex County 208 water quality management planning program; Addendum to: task 5 final draft report low flow modeling: Upper Millstone River, Lower Millstone River, Raritan River
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1977

description: The Task 5 modeling report contained a description of the application of a model previously developed by Lawler, Matusky and Skelly Engineers (LMS) and subsequently modified, to the Upper and Lower Millstone Rivers. The report documented the physical characteristics of these rivers, the conversion of these characteristics to a basic model, the evaluation of model parameters based on low flow sampling of the two rivers, and the calibration and verification of the models with observed dissolved oxygen (DO) profiles.This addendum report discusses:Section II - Model Program Change - the omission in the model and its revision.Section III - Upper Millstone River: a recalculation of kr , kn' and k2, final verification results, and  comparison of these results to those in the Task 5report.Section III -·Lower Millstone River - reevaluation of parameters, final verification results, and comparison of these results to those in the Task 5 report.Section IV - Waste Load Allocation - a documentation of the effect that the corrections to the model have on the DO profiles reported in the allocation procedure report.
Middlesex 208 study eutrophication (task VII)
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1976

description: The objective of the Task VII studies (Eutrophication Analysis) is to identify areas of actual and potential eutrophication, to investigate area impoundments, and to provide guidelines for the allocation of allowable nutrient loadings. Initially, the project concentrated on standard eutrophication indices (nutrients, plankton, chlorophyll, transparency), but it has been expanded to include examination of sediment nutrients and aquatic macrophyte distribution patterns, because of the importance of these factors in the impoundments in the study.Eight impoundments were selected for detailed examination during theeutrophication program. Data concerning diurnal oxygen concentrations, water and sediment chemistry, phytoplankton pigments and abundance, and macrophyte growth were collected from these impoundments during October and March. The number of samples collected for each type of analysis from the selected impoundments is indicated in Table 2.
Elucidation of neural circuits underlying nicotine reward and relapse
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Though many smokers report wanting to quit, only a small percentage are able to remain abstinent long-term. This is because a variety of internal factors and social cues combine to trigger relapse to smoking or nicotine use. The most promising therapeutic approach to increase the efficacy of quitting includes both behavioral therapy and pharmacological approaches, including the drug Chantix (varenicline). However, the drug has significant side effects which cause some patients to not take the drug as prescribed, and the drug does not appear to work equally well in all people. An improved drug that has the positive effects on smoking cessation but without the side effects may help to alleviate these issues. However, this requires an understanding of how varenicline works on the brain to reduce rates of relapse. Currently, we do not have sufficient knowledge of how varenicline works in the brain to develop such a drug. Thus, our research aims to bring us one step closer towards this goal.

 In this proposal, we aim to understand how varenicline works in the brain to reduce rates of relapse. We will use a rodent model of nicotine taking, whereby mice learn to self-administer nicotine by pressing a lever that is associated with a cue light. After the behavior is extinguished (pressing the lever no longer delivers drug), the mice will be presented with the cue light that the mice have associated with nicotine use. This normally causes mice to vigorously press the lever for nicotine rewards, causing a reinstatement of nicotine-seeking behaviors. We will measure brain-wide activity in animals receiving varenicline or not prior to cue-induced reinstatement to identify target sites in the brain that may be involved in reinstatement. We will then conduct focused activity manipulations on these brain cells to test if reducing activity in this defined cell population can have the same effects on reinstatement behavior as varenicline. These results would provide cellular targets that we could investigate further to identify potential drugs that can specifically affect these cells with little to no effect on other cells in the brain.
Additional file 1: Table S1. of Transcriptomic study of Salmonella enterica subspecies enterica serovar Typhi biofilm
Creators: name: Khee Chian Jason Chin
name: Taylor, Todd
name: Hebrard, Maxime
name: Kogaan Anbalagan
name: Dashti, Marjan
name: Phua, Kia
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Expression data for all genes found to be statistically significant. (DOCX 47Â kb)
Production Farming Issues
Creators: name: Cook, Alyssa
name: Jackson, Rachel
name: Adubato, Amanda
name: Kuehne, Patrick
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: The goal was to discuss production farming issues and to develop a business plan for a safe and humane factory farm.
description: Farms used to be family owned with animals treated kindly and no antibiotics or inhuman conditions. However, with America’s obsession of overproduction and high economic value, factory farms have been developed instead.  Factory farms started in the 1920’s with chickens, allowing farmers to raise them inside while feeding them vitamin supplements, vaccines, and antibiotics. During this time period the discovery of pesticides made it easy to produce the large quantities of food needed for these animals.  From 1990 to 2005 the contribution of factory farms to world meat production rose from 30% to 40%. A factory farm’s goal is to produce massive amounts of food and meat to package and send off to big named industries such as Tyson and Purdue. However, the mistreatment of animals and the inhumane conditions of these farms is often overlooked. In order to keep up with production, these companies are manipulating innocent animals. There are no definite rules for agriculture animals. These farms get away with overcrowding animals and grinding them up alive when they are not considered useful. Also, the caging of animals has become a concern. Therefore, these issues need to be addressed and a business plan needs to be proposed to develop a tranquil farm.
Zenicomus ignicolor Galileo & Martins 1988
Creators: name: Groll, Elisa Von
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Zenicomus
Zenicomus ignicolor

description: Zenicomus ignicolor Galileo & Martins, 1988
Galileo & Martins, 1988b:510, figs 18–23, 58.
Paratype ♀, BRAZIL, Espírito Santo: Linhares, X.1972, P. C. Elias col. (MCNZ 122.878).
description: Published as part of Groll, Elisa Von, 2017, Catalogue of Coleoptera type specimens housed in the collection of the Museu de Ciências Naturais, Fundação Zoobotânica do Rio Grande do Sul, Brazil, pp. 439-473 in Zootaxa 4318 (3) on page 450, DOI: 10.11646/zootaxa.4318.3.2, http://zenodo.org/record/887750
Proper Disposal of Medications
Creators: name: Estrella, Brian
name: Rahman, Minhazur
name: Ng, Kevin
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: The Risks of Improper Disposal and the Benefits of Take-Back Programs
description: American household. What many people fail to realize is that these medications have expiration dates and must be properly disposed of. As the use of medication becomes more prevalent in our society a major problem is occurring: what should a person do with expired medication? Recent trends in the United States have shown that children ages 12 to 1& are likely to abuse prescription drugs more than all other illicit drugs except marijuana. These same studies have shown that children in this age group are likely to obtain these drugs from the home. Other studies have been conducted, showing small amounts of antibiotics in groundwater. To combat these issues, the United States government has recently passed a law called The Secure and Responsible Drug Disposal Act. This law allows local pharmacies to take back prescription and over-the-counter drugs for proper disposal. Our goal for this project is to raise awareness among our friends, students, and peers about the dangers associated with improper medical waste disposal. We hope to accomplish this by writing to the corporate headquarters of local pharmacies, compiling this classepedia document, and through the production of documentary and instructional videos on how to properly and safely dispose of any drugs.
The NEW Puppy Lemon Law: A Universal Solution to Puppy Mill in discrepancies
Creators: name: Redelico, Brittany
name: O'Connor, Alyson
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Finally, a common law that all states will be mandated to abide by, has been implemented primarily for the protection of both puppy and owners rights and well-being!
description: Our issue was a big one, with many complex parts and sections.  First and foremost, the puppy lemons laws that are currently in effect are not comprehensive and cohesive.  They can range from very broad and flexible, to very rigid and strict.  There is a lot of room for loop holes and manipulations of the regulations due to the vast array of differences among state requirements.  Puppy purchasers are left vulnerable and many times taken advantage of by the sellers.  The puppies are being mistreated and suffering many forms of abuse because of the holes in the existing laws.  Only the puppy supplier benefits from the laws most time.  Our solution to this problem is to create one universal puppy lemon law that all states will be mandated to abide by.  It will be a combination of strong points of some of the better current lemon laws and also very crucial original points that are left out of almost all of them.  Most importantly our common law will serve primarily in protecting the rights and safety of the puppies and their owners, something that is not covered in any other lemon law. This stable strong bill will not allow for breaches or loop holes, and will hopefully urge consumers to stray away from puppy mills and stores, and to ultimately adopt puppies from shelters.
Phyllonorycter deschkai Triberti 2007
Creators: name: Bryner, Rudolf
name: Kopp, Andreas
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Gracillariidae
Phyllonorycter
Phyllonorycter deschkai

description: 1239a Phyllonorycter deschkai Triberti, 2007 – WA
Salgesch (VS), Pfynwald, 540 mü.M., 610/127, 5.7.2014, am Licht, GP WI 1280 Weibchen (leg. W. Wittland). Ein weiterer Nachweis in Mergoscia (TI), 760 m ü. M., 780/118, 22.8.2017 (leg. K. Grimm).
description: Published as part of Bryner, Rudolf & Kopp, Andreas, 2023, Aktualisierung der Checkliste der Schmetterlinge (Lepidoptera) der Schweiz, pp. 39-60 in Entomo Helvetica 16 on page 43
Tobacco-related risk and cancer-related illness perceptions among low-income smokers
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tobacco use remains the leading cause of preventable disease and premature death in California (CA). The most disadvantaged are the most affected. The rate of smoking in CA's population is 11% compared to up to 70% among those who have experienced homelessness. Tobacco-related diseases are the leading causes of morbidity and mortality among this group. Approximately 66% of people who have experienced homelessness report concurrent use of alternative tobacco products such as blunts, e-cigarettes, and roll-your-own. Concurrent use of these products is associated with worse health consequences than cigarette-only smoking, highlighting a need to understand how the use of these influence cigarette smoking in this population. However, we know little about this groups’ understanding of the harm caused by these products. Behavioral medicine can provide frameworks to elicit thoughts and emotions associated with behavior (quitting smoking to reduce cancer risk). The proposed work uses qualitative research method to identify metaphors that resonate with the lived experience of homeless individuals in order to characterize their tobacco-related risk, addiction, and harm perceptions. These findings can inform tobacco-related health warnings tailored to this population. We plan to explore alternative tobacco product use and risk, addiction, and harm perceptions of these products and response to health communication messages around tobacco use among homeless-experienced smokers. We will invite 30 individuals to join in an in-depth, semi-structured interview on use of alternative tobacco products; comparison of these products' risk to smoking cigarettes; tobacco-related risk, addiction, and harm perceptions; cancer-related beliefs and worry; and response to health communications around tobacco use. This proposal will provide mentored training to Dr. Durazo in qualitative research method and metaphor analysis. With the focus on a group with high prevalence of health conditions and substance use, he will be set to be a well-rounded health scientist. These data will also provide an examination of tobacco-related thoughts, emotions, risk perceptions and perceived efficacy of health communication messages, which together with training will launch Dr. Durazo on a pathway to become an independent researcher developing health communications to reduce tobacco use among this group.
Pushing for Support of Medical Marijuana
Creators: name: Detwiler, Phillip
name: Raden, Kayla
name: Gil, Dan
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: The negative stigma associated with marijuana use and its users prevents doctors from being able to make objective decisions about whether or not marijuana use is appropriate for their patient.
description: Marijuana has been used for hundreds of years as a therapeutic treatment to alleviate pain and nausea.   Although there is a potential for users to become addictive or develop certain undesirable side effects from using marijuana as a treatment, the same danger potential also remains with many of the other drugs that are commonly prescribed to alleviate pain.  Many of these drugs even cause further dangers due to their addictive nature and potential for dependency.  Marijuana can give AIDS patients the appetite to eat again and glaucoma patients relief, however, because our government wants to control what medications are illegal or legal, without taking notice to scientific data, many patients remain in pain while being treated with dangerous prescriptions.Our service project aims to explore the negative stigma associated with marijuana use and its users and to try and explore why that negative association exists, even when it has been scientifically proven to be a great medical treatment.  We developed three separate surveys that compared the different treatment options associated with three diseases:  glaucoma, rheumatoid arthritis, and Alzheimer’s disease.  The survey presents different treatment options for each medical condition and allows the survey-taker to make an unbiased and completely informed decision, since each treatment is simply labeled by #1, #2, or #3.  We want to see what drug a person would choose if they did not know anything about it other than its effectiveness and side effects.
Additional file 4: Figure S1. of Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns
Creators: name: Li, Alexander
name: Hanchard, Neil
name: Furthner, Dieter
name: Fernbach, Susan
name: Mahshid Azamian
name: Nicosia, Annarita
name: Rosenfeld, Jill
name: Muzny, Donna
name: DâAlessandro, Lisa
name: Shaine Morris
name: Jhangiani, Shalini
name: Dhaval Parekh
name: Franklin, Wayne
name: Lewin, Mark
name: Towbin, Jeffrey
name: Penny, Daniel
name: Fraser, Charles
name: Martin, James
name: Eng, Christine
name: Lupski, James
name: Gibbs, Richard
name: Boerwinkle, Eric
name: Belmont, John
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Distribution of rare sites within LSL cases. Adobe PDF. (PDF 208Â kb)
Raising Awareness in an Effort to Reduce Food Waste
Creators: name: Patel, Neil
name: Patel, Birju
name: Phillips, Kyle
name: Smith, Hilary
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Our project is attempting reduce food waste by raising awareness of the benefits of conscious food practices and implementing a program that will allow donations of unused food.
description: The issue of food waste is a growing concern throughout America.  According to the U.S. Department of Agriculture’s Food Loss Project, Americans throw away more than 25 percent — some 25.9 million tons — of all the food we produce for domestic sale and consumption.  We contacted Rutgers catering service in an effort to donate unused food to a local food rescue mission, such as Table To Table, after one of their events.  To increase awareness we also made and handed out pamphlets all throughout Rutgers including restaurants on Easton Avenue. Being proactive doesn’t require much effort or time and raising awareness is great first step in reducing the amount of food waste.
Functional Role of a Human Polymorphism in the Alpha6 NAChR Subunit in Adolescent Nicotine Seeking
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The use of nicotine and tobacco products is a major public health concern, given a recent exponential rise in the rate of electronic cigarette use among teens. Since adolescent nicotine exposure can enhance drug consumption later in life, it is especially important to study the molecular mechanisms mediating adolescent nicotine use. Large-scale human candidate gene studies reveal that a common genetic variant in the alpha6 nicotinic acetylcholine receptor subunit (nAChR) (encoded by the Chrna6C123G gene, rs2304297) plays a role in adolescent nicotine/tobacco use. The corresponding alpha6 nAChR protein is present in dopamine reward neurons in the brain, suggesting that modifications in its quantity and/or function may influence nicotine effects on addiction-related neurocircuitry. To test this hypothesis, my laboratory has engineered a genetically humanized Chrna6C123G mutant rat line. The humanized line replicates the genetic variation in humans and will be used to determine how variation in Chrna6C123G affects adolescent nicotine use. Our recent data using this novel rat line illustrates that animals that carry the higher risk version of the Chrna6C123G gene show enhanced nicotine intake, while animals with the lower risk version of the gene show reduced nicotine intake. We will study whether Chrna6C123G variation influences nicotine seeking behavior by affecting alpha6 nAChR levels and dopamine release in brain reward regions, and how this relates to craving during drug relapse. Understanding the role of Chrna6C123G variations in adolescent nicotine addiction is increasingly important as teen vaping has escalated dramatically, and may lead to improved prevention and intervention strategies.
Argyresthia svenssoni Bengtsson & Johansson 2012
Creators: name: Bryner, Rudolf
name: Kopp, Andreas
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Argyresthiidae
Argyresthia
Argyresthia svenssoni

description: 1435a Argyresthia svenssoni Bengtsson & Johansson, 2012 – GR
Schmid (2016b): Entomo Helvetica 9: 147.
description: Published as part of Bryner, Rudolf & Kopp, Andreas, 2023, Aktualisierung der Checkliste der Schmetterlinge (Lepidoptera) der Schweiz, pp. 39-60 in Entomo Helvetica 16 on page 44
Isotomodes korkorensis Arbea & Kahrarian 2015
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Isotomodes
Isotomodes korkorensis

description: Isotomodes korkorensis Arbea & Kahrarian, 2015
– Isotomodes korkorensis Arbea & Kahrarian, 2015b: 75.
KS: Arbea & Kahrarian 2015b.
Ecology and habitat in Iran: soil and leaf litter in oak forest.
General distribution: species known only from type locality (Arbea & Kahrarian 2015b).
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 45, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
Relieving the Burden of Weight Stigma
Creators: name: Hainutdzinava, Natallia
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Dealing with the Problem of Weight-based Bullying in Schools and Taking Actions to Initiate Changes in Anti-Bullying Bills.
description: The epidemic of obesity is spreading with a tremendous speed in our society, and is especially vivid among young population. As a direct outcome of having extra weight, children encounter weight-based bullying in schools.  Today weight discrimination is compared to racial harassment as it is 66% larger than it used to be. Not only such negative behavior diminishes children mood and encouragement in any weight-loss and lifestyle changes, but also it impacts children’s psychological status. Statistics shows that bullied child develops depression, low self esteem, eating disorders and more prone to suicide attempts. Besides, future lives of stigmatized obese children are getting compromised and these children on average spend fewer years in education, marry less often and have lower socioeconomic status. The project focused on analyzing the problem as well as what is being done to address it nationwide and specifically in the state of New Jersey. A recently introduced Bill No 3466 targets bullying prevention in schools and may lead to many important changes in school environment, decreasing bullying and hopefully suicide attempts. However, the bill when describing bullying does not add weight in the protected categories. That is why the service part of the project focused on contacting legislators in order to amend the bill and include weight category in the definition of bullying.