cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Investigating the orchestration of the inflammatory response: a role for chemokine receptors CCR1, CCR2, CCR3 and CCR5
Creators: name: Bartolini, Robin
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: chemokines, chemokine receptors, CCR1, CCR2, CCR3, CCR5, immune system, leukocytes, migration, chemotaxis, inflammation.

description: Despite over 20 years of pharmaceutical targeted research, no antagonist of inflammatory chemokine receptors (iCCR) has been licensed for use in treating inflammatory diseases. Marked promiscuity of ligand binding, simultaneous expression of multiple chemokine receptors in individual leukocytes and the inability to generate compound receptor knock out mice make it almost impossible to discern the function of a specific iCCR (especially for inflammatory CC chemokine receptors CCR1, CCR2, CCR3 and CCR5). To address this complexity, two novel mouse models have been recently developed at the Chemokine Research Group: a full iCCR-/- strain in which the whole chromosomal CC-iCCR cluster has been deleted, (resulting in a compound CCR1, CCR2, CCR3 and CCR5-/- mouse) and a novel iCCR fluorescent reporter strain, which expresses specific fluorescent proteins under the endogenous iCCR promoters. Experiments on the iCCR-/- have provided a ‘clean slate’ to assess the development of the immune response in the absence of CCR1, CCR2, CCR3 and CCR5, while studies on the iREP strain allowed for direct visualisation of changes in iCCR expression on the surface of several leukocyte subsets. The findings presented in this thesis not only validate our current understanding of the crucial roles of CCR2 and CCR3 in the mobilisation of monocytes and eosinophils from the bone marrow to the site of inflammation, but also provide clues on the role of CCR1 in monocyte trans-endothelial migration and describe a novel role for iCCRs in the proliferation and differentiation of dendritic cells and macrophages in vitro. More studies on these new iCCR mouse models will provide clarity on our current understanding of the orchestration of the CC-chemokine driven inflammatory responses, and the results will not only increase our understanding of basic chemokine biology, but could also inform future pharmacological intervention on the chemokine system.
title: 03_0766
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
The National Forum has published a new focused research report A Current Overview of Recognition of Prior Learning (RPL) in Irish Higher Education
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: This report details an exploration of the current practice relating to the recognition of prior learning in Irish higher education. The research includes a review of the published policies of higher education institutions, their public-facing information as well as an analysis of the details of the mission-based performance compacts outlining goals and objectives for higher education institutions from 2014 to 2016.In-depth interviews with practitioners in higher education institutions were conducted to explore the implementation of RPL in practice. An exploration of processes relating to identification, evidencing, assessment, and recognition of experiential learning by selected employer professional bodies was undertaken.
Additional file 1: of Variance component analysis to assess protein quantification in biomarker validation: application to selected reaction monitoring-mass spectrometry
Creators: name: Klich, Amna
name: Mercier, Catherine
name: Gerfault, Laurent
name: Grangeat, Pierre
name: Beaulieu, Corinne
name: Degout-Charmette, Elodie
name: Fortin, Tanguy
name: MahĂŠ, Pierre
name: Giovannelli, Jean-FranĂ§ois
name: Charrier, Jean-Philippe
name: Giremus, Audrey
name: Maucort-Boulch, Delphine
name: Roy, Pascal
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: The full details for sample preparation and SRM analysis. (DOCX 16Â kb)
MOESM1 of Clinical evaluation of haploidentical hematopoietic combined with human umbilical cord-derived mesenchymal stem cells in severe aplastic anemia
Creators: name: Xu, Lixin
name: Liu, Zhouyang
name: Wu, Yamei
name: Yang, Xueliang
name: Cao, Yongbin
name: Li, Xiaohong
name: Yan, Bei
name: Li, Songwei
name: Da, Wanming
name: Wu, Xiaoxiong
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Additional file 1: Table S1. Pre-transplant characteristics of patients and their donors.
title: Acute myocarditis associated with Covid-19 vaccination
Creators: name: Gonzalez-Cardenas, Eduardo
Publisher: name: EURORAD
Year: 2022
Subjects: subject: Cardiovascular
subject: Cardiac
subject: MR
subject: Inflammation
subject: Clinical Cases

description: Clinical History: A 26-year-old man with no remarkable past medical history presented to the Emergency Department with a 24-hour history of left parasternal chest pain. No fever, cough or dyspnea. EKG was normal but blood work showed elevated troponin and C-reactive protein values. Echocardiography was performed and showed hypokinetic movement of the lateral wall. He was then referred for cardiac magnetic resonance (CMR) imaging. The patient had received immunization for COVID (Moderna) 3 weeks prior to the event.

description: 26 years, male
A Conceptual Model for the Professional Development of those who Teach in Irish Higher Education: Report on the Findings of the Consultation Process
Creators: name: :: National Forum For The Enhancement Of Teaching And Learning In Higher Education
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 160506 Education Policy
subject: FOS: Political science
subject: Education

description: This report presents a conceptual model for professional development, based on the findings of a comprehensive national consultation process. It highlights the sector’s understanding of professional development, identifies some underlying values for the model and suggestions some teaching and learning domains for structuring the process. It presents some of the ideas and challenges for the model’s implementation and it concludes with some next steps in the professional development process.
DNA Methylation Changes in Response to Ribosomal DNA Copy Number Variation and in Premature Aging Disorders
Creators: name: Razzaq, Aleem
Publisher: name: Manara - Qatar Research Repository
Year: 2024
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyze and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless, rDNA displays high inter-individual CN variation that could influence human health and disease. CN alterations in rDNA have been hypothesized as a possible factor in autism spectrum disorders (ASD) and was shown to be altered in Schizophrenia patients. We tested whether whole genome bisulfite sequencing can be used to simultaneously quantify rDNA CN and measure DNA methylation at the 45S rDNA locus. Using this approach, we observed high inter-individual variation in rDNA CN, and limited intra- individual copy differences in several postmortem tissues. Furthermore, we did not observe any significant alterations in rDNA CN or DNA methylation in Autism Spectrum Disorder (ASD) brains and in neurons or oligodendrocytes from Schizophrenia patients. However, our analysis revealed a strong positive correlation between CN and DNA methylation at the 45 rDNA locus. In this study, a positive association between rDNA CN variation and DNA Methylation was detected in multiple tissues. This should shed light on a possible dosage compensation mechanism controlled by DNA methylation that silences additional rDNA copies to ensure homeostatic regulation of ribosome biogenesis.Moreover, a genome-wide DNA methylation was performed using Infinium Methylation EPIC arrays in 15 progeroid laminopathies patients (Classical HGPS and non- classical HGPS) where 61 significant CpG sites were observed. These regions showed enrichment for biosynthetic processes of phospholipid, phosphatidylinositol, glycerolipid, and glycerophospholipid, phosphatidylinositol metabolic process, and sarcoplasmic reticulum. This should help elucidate molecular processes linked with premature aging in progeroid syndromes and processes implicated in normal biological aging.
MOESM3 of Identification and validation a TGF-Î˛-associated long non-coding RNA of head and neck squamous cell carcinoma by bioinformatics method
Creators: name: Huang, Teng
name: Huang, Wei
name: Lu, Hong
name: Zhang, Bi-yun
name: Ma, Jun
name: Zhao, Di
name: Wang, Yi-jun
name: Yu, Da-hai
name: He, Xia
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3. Demographics and clinical characteristics of TCGA HNSCC cohort.
Two Views of a Tree Fallen on Ella Osborne's House, September 21, 1938
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 1938
Subjects: East Hampton
Trees
Osborn Family
Hurricanes
Debris
Fences

description: These images show two views of a fallen tree on Ella Osborn's house during the hurricane on September 21, 1938.
title: Solid pseudopapillary epithelial neoplasm of pancreas with hepatic metastasis: A rare case
Creators: name: gupta, kushal
Publisher: name: EURORAD
Year: 2022
Subjects: subject: Abdominal imaging
subject: Abdomen
subject: Pancreas
subject: CT
subject: Ultrasound
subject: Clinical Cases

description: Clinical History: A 24 years-old-female presented with abdominal discomfort and pain for last 6 months. This was associated with recurrent vomiting. No history of jaundice/GI Bleed/ anorexia/ abdominal distension.

description: 24 years, female
INDIVIDUALISM: THE PILLAR FOR THE CONSTRUCTION OF A LIBERAL STATE
Creators: name: RUI MIGUEL ZEFERINO FERREIRA
Publisher: name: figshare
Year: 2017
Subjects: subject: Law
subject: FOS: Law

description: This article aims to bring to the knowledge one the most criticized and misunderstood ideas of legal and political science – the individualism. There are several perspectives through which individualism can be studied, from its moral and social implications to political and economic ones, but these are the last two strands that the text will explore. The purpose of this is to endow the current doctrine with a dogmatic and to allow the construction of a postmodern State centered on the principle of individual freedom of the individuals that compose it.
Unhindered copper uptake by glutaraldehyde-polyethyleneimine coatings in an artificial seawater model system with adsorbed swollen polysaccharides and competing ligand EDTA
Creators: name: Simarpreet Kaur
name: Kempson, Ivan M.
name: Lindén, Johan B.
name: Larsson, Mikael
name: Nydén, Magnus
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Shortly after a surface is submerged in the sea, a conditioning film is generally formed by adsorption of organic molecules, such as polysaccharides. This could affect transport of molecules and ions between the seawater and the surface. An artificial seawater model system was developed to understand how adsorbed polysaccharides impact copper binding by glutaraldehyde-crosslinked polyethyleneimine coatings. Coating performance was also determined when competed against copper-chelating EDTA. Polysaccharide adsorption and copper binding and distribution were investigated using advanced analytical techniques, including depth-resolved time-of-flight secondary ion mass spectroscopy, grazing incidence X-ray absorption near-edge spectroscopy, quartz crystal microbalance with dissipation monitoring and X-ray photoelectron spectroscopy. In artificial seawater, the polysaccharides adsorbed in a swollen state that copper readily penetrated and the glutaraldehyde-polyethyleneimine coatings outcompeted EDTA for copper binding. Furthermore, the depth distribution of copper species was determined with nanometre precision. The results are highly relevant for copper-binding and copper-releasing materials in seawater.
title: Clinical presentation and diagnostics of cattle with suspected Johne’s disease
Creators: name: Baro Basora, Joan
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Johne's, paratuberculosis, cattle, ill thrift, diarrhoea, poor body condition, serology, PCR, culture, histology, ZN.

description: Johne’s disease, caused by the bacteria Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic, wasting condition of ruminants, which is characterized by the clinical signs of weight loss and diarrhoea. The economic losses associated with the disease in the cattle and sheep industry, worldwide spread and high prevalence make Johne’s disease an important disease to investigate. Additionally, MAP has been isolated from humans suffering of Crohn’s disease and zoonotic potential of MAP in humans is still under debate. Currently available diagnostic tests have impaired sensitivity, particularly in preclinical stages of disease and thus a prompt and effective identification of infected animals is difficult. The primary aim of this work was to analyse and describe the history, clinical presentation and diagnostic test results of cattle submitted to a veterinary teaching hospital that showed clinical signs consistent with Johne’s disease. The secondary aim was to compare diagnostic test results to the gold standard, faecal culture. Fifty-nine out of the 192 cattle referred over 18 months met the inclusion criteria for the study, which was poor body condition or a history of weight loss and diarrhoea. A total of 52 females and seven males, comprising 34 beef and 25 dairy cattle were studied. All cattle had a full clinical examination, biochemistry blood analysis, Johne’s blood serology and faecal PCR and culture. They were inspected post-mortem and the ileo-caecal valve and proximal lymph node were examined histopathologically using a haematoxylin-eosin (H/E) and Ziehl-Neelsen (ZN) staining. Results from clinical examination, albumin and globulin serum concentrations, Johne’s serology, PCR, post-mortem examination and histopathology examination were compared to faecal culture results. Thus, this study reported all the clinical and diagnostic test results commercially available for Johne’s disease in cattle, such study was not reported before. Results showed inconsistent results between PCR and culture tests. However, both blood serology and H/E slide examination tests had a specificity of 100%. This work should help inform clinicians on interpretation of Johne’s diagnostic testing in clinical cases and may have implications for Johne’s control programmes relying on the results from the diagnostic tests reported.
The impact of sharing supplementary datasets and speaking outside the echo chamber // Urban Studies and Planning
Creators: name: Rae, Alasdair
name: Hardeman, Megan
name: Team Figshare
Publisher: name: figshare
Year: 2018
Subjects: subject: 160404 Urban and Regional Studies (excl. Planning)
subject: FOS: Social and economic geography
subject: 120599 Urban and Regional Planning not elsewhere classified
subject: 140218 Urban and Regional Economics
subject: FOS: Economics and business

description: The impact of sharing supplementary datasets and speaking outside the echo chamber - a figshare case study of Alasdair Rae's Urban Studies and Planning research.
Microbial fouling and corrosion of carbon steel in deep anoxic alkaline groundwater
Creators: name: Rajala, Pauliina
name: Bomberg, Malin
name: Vepsäläinen, Mikko
name: Carpén, Leena
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Understanding the corrosion of carbon steel materials of low and intermediate level radioactive waste under repository conditions is crucial to ensure the safe storage of radioactive contaminated materials. The waste will be in contact with the concrete of repository silos and storage containers, and eventually with groundwater. In this study, the corrosion of carbon steel under repository conditions as well as the microbial community forming biofilm on the carbon steel samples, consisting of bacteria, archaea, and fungi, was studied over a period of three years in a groundwater environment with and without inserted concrete. The number of biofilm forming bacteria and archaea was 1,000-fold lower, with corrosion rates 620-times lower in the presence of concrete compared to the natural groundwater environment. However, localized corrosion was detected in the concrete–groundwater environment indicating the presence of local microenvironments where the conditions for pitting corrosion were favorable.
title: 02_0076
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Allen-Collinson, J (2017) Injured, pained and disrupted bodies, in M L Silk, D L Andrews and H Thorpe (eds), Routledge Handbook of Physical Cultural Studies, London: Routledge.tem
Creators: name: Allen-Collinson, Jacquelyn
Publisher: name: figshare
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology

description: Introduction All too commonly, pain and injury constitute integral components of participation in many sports and physical cultures, even those not usually constructed as dangerous or ‘high-risk’. This was highlighted in the news in 2014 by the untimely death of the young Australian cricketer Phillip Hughes, who was struck on the neck by a ball from a pace bowler while batting in a domestic game, and died two days afterward, never regaining consciousness. Gone. Killed playing the game he loved. While such a catastrophic injury is thankfully rare in cricket, nevertheless, pain, injury and bodily disruption are widespread and often normalized within sport and physical cultural domains, where a ‘culture of risk’ can be argued to prevail. Adopting a transdisciplinary approach commensurate with PCS, this chapter explores some of the extant sociological, anthropological, and social-psychological research on active embodiment in relation to injured, pained and disrupted bodies. From the myriad different approaches available in researching this area, here I focus upon the impact of identity disruption and the role of ‘identity work’ in dealing with the injured body in the physical-cultural context of distance running, drawing on data from two automethodological projects. The concept of ‘identity work’ has been utilized within various disciplines, and here is theorized from a symbolic interactionist perspective specifically. This sociological theoretical framework investigates the relational, processual and subjective elements of identity and embodiment, and thus coheres with the PCS enterprise. It offers powerful analytic insights in examining the injured and pained body as experienced within physical cultures, including within the normative structures of those cultures.
Additional file 2: of Variance component analysis to assess protein quantification in biomarker validation: application to selected reaction monitoring-mass spectrometry
Creators: name: Klich, Amna
name: Mercier, Catherine
name: Gerfault, Laurent
name: Grangeat, Pierre
name: Beaulieu, Corinne
name: Degout-Charmette, Elodie
name: Fortin, Tanguy
name: MahĂŠ, Pierre
name: Giovannelli, Jean-FranĂ§ois
name: Charrier, Jean-Philippe
name: Giremus, Audrey
name: Maucort-Boulch, Delphine
name: Roy, Pascal
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Virology

description: Number of transitions and peptides per protein and the percent of missing and zero values among protein concentration measurements. (DOCX 18Â kb)
title: An interdisciplinary approach for designing selective insecticides for bee safety considering mechanistic processes
Creators: name: Elston, Charlotte
name: Miranda, Jacob
name: Thompson, Helen
name: Talmann, Lea
name: Pym, Adam
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2025
Subjects: subject: 630

description: Julius-Kühn-Archiv, vol. 481Hazards of pesticides to bees, 16th International Symposium of the ICP-PR Bee Protection Group, - Proceedings -; 15th - 17th October, 2024; Sevilla (Spain), p. 43
Figure S1 from The Opiliones tree of life: shedding light on harvestmen relationships through transcriptomics
Creators: name: Fernández, Rosa
name: Sharma, Prashant P.
name: Tourinho, Ana Lúcia
name: Giribet, Gonzalo
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60408 Genomics

description: Figure S1. Topology as in Figure 2 showcasing support for shallower nodes. Color codes for support values are indicated in the legend
title: De Volonté & the vampire bite: how Gothic vampire literature of the 19th century influences female members of the Goth subculture
Creators: name: Barclay, Hayleigh
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Vampire, Gothic literature, 19th century literature, Goth subculture, feminism, Dracula, Carmilla, female vampire, Anne Rice, Twilight, gender, subculture, identity, folklore, LGBT, Victorian.

description: This thesis consists of two separate elements which, when combined, form my practice-based research into 19th Century Gothic vampire literature, and the contemporary Goth subculture. The novel is set on a fictional Scottish island during the 19th Century, and features a female assassin who discovers she’s part of a long lineage of vampires. Only by confronting her own fears, uncovering an ancestral curse, and stopping a war designed to wipe out her kind, can she find her true identity. The critical component investigates if/how the identity of female contemporary Goths is inspired by 19th Century literary female vampires. The research uses interview-based data and textual analysis of vampire literature, e.g. Dracula and Carmilla to demonstrate how readers’ interactions with literary characters can provide insight into contemporary social culture and interpretations of the past. Within the study, the analysis demonstrates the opportunities for creative writers to develop and evolve the figure of the literary female vampire to appeal to contemporary female audiences. The interview demographics include individuals who identify as female; between the ages of 18 and 56+; and span 14 countries. By combining the two elements, they work together, to deliver an analysis of contemporary approaches to writing/reading the literary female vampire.
title: Melodic embellishment in Mozart
Creators: name: Bandy, Dorian Komanoff
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Mozart, embellishment, improvisation, performance, historical performance, epistemology, aesthetics, interpretation.

description: This dissertation presents a general account of embellishment in Mozart’s oeuvre. Chapter 1 lays the theoretical groundwork, distinguishing embellishment from the related techniques of variation, diminution, and structural elaboration. It also examines the various epistemological barriers involved in studying centuries-old improvisations, and situates the project within the culture of historical performance. Chapter 2 examines the relationship between Mozart’s compositional process and his piano technique, arguing that studies of his notated works can, if handled judiciously, shed light on his performing practices. Building upon this unification, Chapter 3 focuses the methods by which embellishment gestures can be discerned in Mozart’s notated works. Chapter 4 examines Mozart’s embellishment protocols, from local gestures such as trills and turns, to large-scale pacing, relating these procedures to broader issues including instrumental technique, operatic characterisation, and the compositional process. Chapter 5 compares Mozart’s embellishments with those by his contemporaries (Vogler, Haydn), students (Ployer, Hummel), and successors (Beethoven). Finally, Chapter 6 considers the role of embellishment in Mozart’s musical aesthetic as a whole. It argues that embellishment provides a lens through which to re-evaluate not only Mozart’s works, but the evolution of musical style, the relationship between analysis and performance, and the role of explanation in musical interpretation.
The impact of sharing supplementary datasets and speaking outside the echo chamber // Urban Studies and Planning
Creators: name: Rae, Alasdair
name: Hardeman, Megan
Publisher: name: figshare
Year: 2017
Subjects: subject: 160404 Urban and Regional Studies (excl. Planning)
subject: FOS: Social and economic geography
subject: 120599 Urban and Regional Planning not elsewhere classified
subject: 140218 Urban and Regional Economics
subject: FOS: Economics and business

description: The impact of sharing supplementary datasets and speaking outside the echo chamber - a figshare case study of Alasdair Rae's Urban Studies and Planning research.
Speciation of arsenic in water and sediments, in some mines within the Pine Creek Geosyncline, Northern Territory Australia
Creators: name: Eapaea, Miro Peter
Publisher: name: Charles Darwin University
Year: 2003

description: This study of arsenic speciation in water and sediments from five mine sites within the Pine Creek Geosyncline (PCG), Northern Territory, examined transportation and fixation of arsenic forms due to one of the following discrete processes:• alkaline (cyanide) seepage from tailings dam;• acid drainage to retention pond prior to overflow;• acid drainage run-off across bushland;• erosion of mineral particulates from small scale mining; and• transport of organic-rich alluvial gold tailings. The study of arsenic species was based on operationally-defined forms in soils, sediment and evaporates and enabled interpretation of the key processes associated with arsenic retention. Modified sediment sequential extraction (Chunguo and Zihui, 1988) and HCl/Chloroform extraction (Chappel et al., 1995) procedures were used to measure the arsenic species as follows : soluble and loosely bound As, Al-As, Fe-As, Ca-As, Fe(OH)3 occluded As, organic bound As and residual As in sediment phases using the sequential As extraction procedure; and As (III), As (V), inorganic As, organic As and As(t) soluble in strong acid using the HC1/chloroform extraction. The arsenic speciation data for 13 species extracted from 117 spatial and 20 depth profile sediment samples and 26 water samples, was used to determine the mechanism of arsenic dispersion occurring at the various mine sites. The study found that the following retention processes were involved in immobilising arsenic dispersion:(i) In wetland systems, as at Tom's Gully gold mine anabranch, through precipitation with iron oxyhydroxides, calcium from alkaline groundwater and organic matter from detrital material; (ii) Utilisation of retention ponds to act as sediment trap to retain arsenic and metal contaminants from alkaline and acidic source seepages as demonstrated at Goodall gold mine. Arsenic levels up to 1 ,700µg/g were held in the form of ferric arsenate, calcium arsenate and residual arsenic; (iii) Seepage should be directed into retention ponds or borrow pits; (iv) High levels of iron and organic matter helped in retention of residual arsenic and other mineral particulates during erosion or controlled process water discharges at Millars Battery Union Reefs mine, McKinlay River Union Reefs mine and MLN 95 Copperfield Creek at Pine Creek; and (v) Natural geomobilisation of arsenic was observed in upstream sediments at Copperfield Creek (5-8µg/g), Mt. Bundey Creek (10-12µg/g), upstream Ryan's Creek (10-12µg/g) and downstream East branch Ryan's Creek (7µg/g). Erosion of mineralisation containing arsenic was observed in the McKinlay River upstream and downstream (23-26µg/g) and upstream Ryan's Creek boundary of MLN 1049 (24-40µg/g). These features, as identified, can be utilised for future mine water management design.
title: Identifying novel antiviral defences against VSV and HIV-1
Creators: name: Aziz, Muhamad Afiq
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: IFN, TF, CC, ISG, VSV, HIV-1.

description: Mammalian cells encode an arsenal of antiviral defences, which can be deployed following sensing of an invading pathogen. These cell autonomous defences are stimulated by interferon (IFN) signalling which activates the expression of interferon-stimulated genes (ISGs) that encode numerous antiviral proteins and can alter the thermal landscape of the host. These ISGs can constrain virus replication, transmission and pathogenesis. However, the function of many ISGs in limiting Vesicular Stomatitis Virus (VSV) and Human Immunodeficiency Virus 1 (HIV-1) infection is incompletely understood. In this study, the role of ISGs and fever responses in restricting VSV and HIV-1 replication were investigated. The IFN system and fever are two interconnected components of the intricate host response to viral infections. In experiments where the incubation temperature was raised to fever-like temperatures, reduced single cycle infection of VSV but not HIV-1 was observed, indicating the possible involvement of host factors that specifically target VSV in these conditions. To further understand how ISGs limit infection, an arrayed ISG expression screen was performed against VSV. This gain-of-function screen revealed TRIM69 as a potent IFN-inducible inhibitor of VSV. Further work identified this inhibition to be highly specific for the VSV Indiana serotype, as VSV New Jersey, DENV-2 and HIV-1 were not inhibited. Using an in vitro evolution approach, a single amino acid substitution in the VSV phosphoprotein, D70Y, conferred complete resistance to the potent inhibitory effect of TRIM69. In addition to screening for VSV restriction factors, HIV-1 antiviral ISGs were investigated. Analysing several candidate ISGs against a lab-adapted HIV-1 identified EHD4 as a host factor that could block the late stages of HIV-1 replication. However, EHD4 was minimally induced by type I IFN in T-lymphocyte cell lines and primary PBMCs, and deletion of endogenous EHD4 in T-lymphocyte cells did not enhance HIV-1 propagation. An in vitro evolution experiment with lab strain HIV-1 revealed that a single amino acid V35I substitution was sufficient to confer near complete resistance to EHD4. Intriguingly, this V35I mutation was also observed in a virus derived from a chronically infected patient which was propagated in the presence of type I IFN. Further analysis indicated that this V35I substitution was not solely responsible for type I IFN resistance in transmitted HIV-1. Finally, an ISG expression screen against paired transmitted founder (TF) and chronic control (CC) HIV-1 viruses identified several ISGs that could specifically target CC virus but not TF virus. Collectively, this work highlights the complexity of the host defences to not only different viruses but also different strains of virus and at different times after infection which may impact viral transmission and pathogenesis.
title: 02_1193
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: Automating the discovery and emergence of life
Creators: name: Asche, Silke
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Origins of life, artificial life, automation, fingerprinting.

description: The processes that led to the emergence of life is a not yet understood question. Bottom up approaches to the problem aim to understand how simple molecular building blocks give rise to complex, organized chemical systems. Historically, this approach has been limited by the combinatorial nature of organic chemistry and laborious analytical processes. In this work, these limitations have been circumvented by leveraging the power of automation to perform long-term, continuous experiments with the aim of constructing artificial life from abiotic starting points. To explore the complexification of simple molecule building blocks into chemical reaction networks, we perform recursive experiments. These are reactions that are periodically replenished with new starting material, thereby forcing the system far from equilibrium. This process leads to more complex product mixtures than non-recursive reactions, by inducing a historical dependence in the reaction network. We built a platform reactor system with in-line analysis, driven by a decision making algorithm and software with minimal human intervention. This gives us the opportunity to perform experiments 24/7, increasing the reaction throughput and screen a large chemical space in a short period of time. Using algorithmic feedback, the autonomous platform can make fast decisions on whether to change the chemical composition and reaction parameters. The ultimate aim of this project is to contribute to find the “missing link” in the progress of bottom-up synthesis of life like systems. The search for increasing complexity using analytical feedback allows us to look for the route by which simple molecules become complex systems, ultimately leading to a chemical to biological transition.
Supporting information for Nietlisbach et al. (2017, Proceedings of the Royal Society B-Biological Sciences): Pedigree-based inbreeding coefficient explains more variation in fitness than heterozygosity at 160 microsatellites in a wild bird population)
Creators: name: Nietlisbach, Pirmin
name: Keller, Lukas F.
name: Camenisch, Glauco
name: Guillaume, Frédéric
name: Arcese, Peter
name: Reid, Jane M.
name: Postma, Erik
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 60408 Genomics

description: Supporting Information 1: Extended methods and results; Supporting Information 2: Determinants of identity disequilibrium; Supporting Information 3: Inbreeding with immigration
Supplementary information S2 (pdf): Additional analyses. from Gaze-contingent reinforcement learning reveals incentive value of social signals in young children and adults
Creators: name: Vernetti, Angelina
name: Smith, Tim J.
name: Senju, Atsushi
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Developmental Biology
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: The supplementary information S2 includes additional analyses investigating the initial exposure to both engaging and non-engaging cues, the proportion of looking time on the reward-predictive cue at pre-test and post-test, the side bias at pre-test and post- test, the children and adults’ impression of the task and the viewing time of the reward (cartoon).
Supplementary Table 1 from A behavioural framework for the evolution of feeding in predatory aquatic mammals
Creators: name: Hocking, David P.
name: Marx, Felix G.
name: Park, Travis
name: Fitzgerald, Erich M. G.
name: Evans, Alistair R.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: Glossary of key terms and functional definitions for the behaviours used during aquatic mammal feeding.
title: Automated ship hull form design optimisation through morphing and evolutionary computation
Creators: name: Ang, Joo Hock
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Hull form design and optimisation, simulation-based design, curve morphing, evolutionary computation, design automation.

description: Eco-friendliness and energy efficiency are now key criteria in the design and construction of all new ships due to stringent environmental regulations aimed at reducing their carbon footprint. An efficient hull form helps in reducing the overall drag acting on a ship, as well as reducing fuel consumption and harmful emissions to the environment. More recently, Simulation-Based Design (SBD) methods have been proposed to improve the efficiency of the hull form design process. However, the entire process still requires considerable human inputs, and success depends heavily on the designer’s experience and knowledge. To address these limitations, an industry-first design automation tool based on Morphing and Evolutionary Computation (MEC) was developed in this thesis. This was achieved by combining a novel two-dimensional (2D) curve morphing method and a Non-dominated Sorting Genetic Algorithm II (NSGA-II) using proven hull form designs as initial starting points. The 2D curve morphing method provides an efficient way to modify the hull form whilst providing more flexible geometric variations. NSGA-II is a multi-objective optimisation algorithm that uses nature-inspired operations to optimise a population of candidate solutions in a generative manner. This tool supplements experienced designers in modifying the shape of the hull form, in a more automated manner, helping them to achieve more diverse and optimal design solutions. Central to the working of MEC are novel crossover and mutation mechanisms, developed using cross-morph and boundary-morph. Together, these two morphing techniques enable geometric manipulation to be performed directly on the hull, instead of modifying the design parameters as is the case in traditional approaches. By applying the two morphing techniques within NSGA-II, more diverse shapes can be discovered, and the entire design process can further be automated. MEC is particularly well-suited for the initial design stage, where shape diversity and efficient performance evaluation are key to finding more optimal designs. The final output of this method is a set of Pareto optimal designs, which can further be refined by the designer. Through digitisation and computational intelligence, it is envisioned that automated design will help to improve the overall design efficiency and capability to produce more efficient and smarter ships in the future.
title: Transnational journeys: changing identities, perceptions and experiences of Malaysian doctoral students studying in the UK
Creators: name: Anuar, Nuramira Binti
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Higher education, student experience, transnationalism.

description: The main questions that the present study seeks to answer are why and how do Malaysian international doctoral students experience their living and learning experiences in the UK, particularly in Scotland, United Kingdom. The study explores participants’ motivations, experiences and future trajectories through Bourdieuian social theory and through the lens of transnational theory. An interpretative, multiple qualitative methodology was used, including semi-structured interviews, email interviews, and online narratives, to explore the participants’ experiences as sojourners. The study found that Malaysian doctoral students pursued their study abroad for the purpose of acquiring a wide range of formal and informal knowledge, as well as for the benefits of self and others. The participants’ microlevel experiences suggest that their ‘habitus’ are fluid, and they are constantly renegotiating their knowledge, perceptions and identities. They also portrayed reflexivity in negotiating their perceptions and experiences by drawing upon previous and present knowledge from both their home and host countries when abroad. It was also found that the participants’ future career pathways and mobility imaginings are influenced relationally by not only family and employment obligations but, also, present experiences as globalized transnational individuals, and also changing mobility imaginings that are bounded by ‘assemblages of powers’ (Robertson, 2013) of both their home and host countries. Finally, the findings suggest a range of intersectional nuances of experience in relation to social identity dimensions such as gender, ethnicity and religion.