Additional file 4 of Multi-system diseases and death trajectory of metabolic dysfunction-associated fatty liver disease: findings from the UK Biobank
Creators: name: Jia, Yu
name: Li, Dongze
name: You, Yi
name: Yu, Jing
name: Jiang, Wenli
name: Liu, Yi
name: Zeng, Rui
name: Wan, Zhi
name: Lei, Yi
name: Liao, Xiaoyang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 4: Table S1. PheWAS of MAFLD and 490 medical conditions. Table S2. Temporal disease pairs in MAFLD individuals. Table S3. Basic characteristics of the dead and surviving participants. Table S4. PheWAS of medical conditions and 7 causes of death. Table S5. Temporal disease pairs in dead individuals with MAFLD. Table S6. PheWAS of MAFLD and 490 disease conditions in heavy drinkers and nonheavy drinkers. Table S7. PheWAS of MAFLD and 490 disease conditions in normal weight and overweight/obese individuals. Table S8. PheWAS of MAFLD and cause of death in normal weight and overweight/obese individuals. Table S9. PheWAS of MAFLD and cause of death in heavy drinkers and nonheavy drinkers. Table S10. Sensitivity analysis of the relationship between MAFLD and 490 medical conditions. Table S11. Sensitivity analysis of the relationship between MAFLD and cause of death. Table S12. PheWAS of nonfibrotic MAFLD and fibrotic MAFLD with 490 medical conditions. Table S13. PheWAS of nonfibrotic and fibrotic MAFLD with causes of death.Table S14. PheWAS of MAFLD with or without MBOAT7 rs641738 (C &gt; T) and 490 medical conditions. Table S15. PheWAS of MAFLD with or without MBOAT7 rs641738 (C &gt; T) and causes of death. Table S16. PheWAS of MAFLD with or without GCKR rs1260326 (C &gt; T) and 490 medical conditions. Table S17. PheWAS of MAFLD with or without GCKR rs1260326 (C &gt; T) and causes of death. Table S18. PheWAS of MAFLD with or without TM6SF2 rs58542926 (C &gt; T) and 490 medical conditions. Table S19. PheWAS of MAFLD with or without TM6SF2 rs58542926 (C &gt; T) and causes of death. Table S20. PheWAS of MAFLD with or without PNPLA3 rs738409 (C &gt; G) and 490 medical conditions. Table S21. PheWAS of MAFLD with or without PNPLA3 rs738409 (C &gt; G) and causes of death. Table S22. Basic characteristics of the participants with and without genetic susceptibility to MAFLD. Table 23. Basic characteristics of the dead and surviving participants with genetic susceptibility to MAFLD. Table S24. PheWAS of genetic susceptibility to MAFLD and 490 medical conditions in males and females. Table S25. PheWAS of genetic susceptibility to MAFLD and cause of death in males and females. Table S26. Temporal disease pairs in individuals with high genetic susceptibility to MAFLD. Table S27. PheWAS of medical conditions and 7 causes of death in individuals with genetic susceptibility to MAFLD. Table S28. Temporal disease pairs in dead individuals with genetic susceptibility to MAFLD. Table S29. Temporal disease pairs in individuals with alcoholic liver disease. Table S30. Temporal disease pairs in individuals with other alcoholic liver diseases.