cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Concise Synthesis of 3,5-Dicyano-6-trifluoromethylpyridine and Preparation of a Mono Thioamide
Creators: name: Hall, Roger G.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Engineering
subject: Biochemistry

description: A concise 3-step synthesis of 3,5-dicyano-6-trifluoromethyl pyridine is reported from commercially available starting materials. Selective conversion of one cyano group into a thioamide offers further scope for derivatization.
Effects of Superabsorbent Polymer on Cyanobacterial Biological Soil Crust Formation in Laboratory
Creators: name: Chan-Ho Park
name: Xinrong Li
name: Jia, Rong Liang
name: Jae-Seoun Hur
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Plant Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology

description: Numerous attempts have been made to control desertification and restore soil by inducing biological soil crusts (BSCs) formation through inoculation with cyanobacteria or application of soil fixing chemicals. In this study, combined application of biological (cyanobacteria) and chemical (superabsorbent polymer: SAP) materials to sand particles was conducted under laboratory conditions. Nostoc sp. was applied to sand at 5 to 25 mg fresh weight (FW)/cm2 and incubated at 25°C under 100 μmol photons m−2 s −1 for 12 hr per day for 3 months. MWD (Mean Weight Diameter) analysis showed that the minimal cell dose for artificial BSCs induction was 10 mg FW/cm2, and the resulting BSC was stable enough to resist various destructive factors. Aggregate stability of the combined biological and chemical treatment (ACSAP) was higher than that of samples treated with Nostoc cells alone (AC) in the fast and slow wetting tests, but less stable than that of AC treatment in the wet stirring test. The SAP showed no harmful effect on Nostoc cell growth because of increased biomass during ACSAP treatment. However, the levels of extracellular polysaccharides (ESP) were lower upon ACSAP treatment than AC treatment. The wet stirring test demonstrated that ESP content was more important than cyanobacterial biomass for maintaining stability of the induced BSC. Overall, this study provides useful information regarding the interaction of Nostoc cells and superabsorbent polymer during artificial BSC formation. The results indicate that future studies investigating application of combined treatment of Nostoc cells and SAP in the field are warranted.
Synthesis, Characterization and Antimicrobial Evaluation of Some Novel 4-Hydroxyquinolin-2(1H)-ones
Creators: name: Magdy A. Ibrahim
name: Hassanin, Hany M.
name: Alnamer, Youssef A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Physics
Biochemistry

description: Vilsmeier-Haack formylation of 3-acetyl-1-methyl-4-hydroxyquinolin-2(1H)-one (2) produced the novel 6-methyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carboxaldehyde (3). Reactions of carboxaldehyde 3 with a diversity of nucleophilic reagents were studied and a variety of products were obtained via ring-opening ring-closure (RORC) sequence. Also, some novel heteroannulated pyrano[3,2-c]quinolines were prepared. Structures of the new synthesized products were deduced on the basis of their analytical and spectral data.
A Concise Synthesis of 3,5-Dicyano-6-trifluoromethylpyridine and Preparation of a Mono Thioamide
Creators: name: Hall, Roger G.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Engineering
subject: Biochemistry

description: A concise 3-step synthesis of 3,5-dicyano-6-trifluoromethyl pyridine is reported from commercially available starting materials. Selective conversion of one cyano group into a thioamide offers further scope for derivatisation.
MLA Institutes on Reading and Writing Pedagogy at Access-Oriented Institutions: The Core Curriculum
Creators: name: Hunt, Mai
Publisher: name: unknown
Year: 2024
Subjects: subject: Reading
subject: Instructional and educational works
subject: Historically Black colleges and universities
subject: Curriculum planning
subject: Writing
subject: Community colleges
subject: Tribal Colleges and Universities Program (U.S.)
subject: Open access
subject: Career development

description: Through the support of the Mellon Foundation and the Social Science Research Council with the National Endowment for the Humanities, the MLA has hosted the Institutes on Reading and Writing Pedagogy at Access-Oriented Institutions (AOIs) to strengthen the teaching of reading and writing at AOIs—community colleges and other colleges that prioritize access over selectivity in admissions. Since 2019, the association has organized these institutes, reaching nearly three hundred participants who either teach at AOIs or who would like to make their teaching careers at them. Through ongoing support from the Mellon Foundation, the MLA will continue this work with with the publication of the core curriculum.
Synthesis of nickel(II) complexes of isatin thiosemicarbazone derivatives: in vitro anti-cancer, DNA binding, and cleavage activities
Creators: name: Amna Qasem Ali
name: Siang Guan Teoh
name: Eltayeb, Naser Eltaher
name: Ahamed, Mohamed B. Khadeer
name: Ams Abdul Majid
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Cancer
Chemistry
Earth and Environmental Sciences
Cell Biology
Biochemistry
Biophysics

description: Six new nickel(II) complexes of thiosemicarbazone Schiff base with isatin moiety [Ni(L1)2–Ni(L6)2] were synthesized through reaction of Ni(II) with (Z)-2-(2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (L1H), (Z)-2-(5-methyl-2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (L2H), (Z)-2-(5-fluoro-2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (L3H), (Z)-N-methyl-2-(5-nitro-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (L4H), (Z)-N-methyl-2-(5-methyl-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (L5H), and (Z)-N-ethyl-2-(5-methyl-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (L6H). The structures of the Ni complexes were characterized through elemental analysis, infrared, and mass spectral data. The structure of the NiL2 complex was further characterized through single-crystal X-ray diffraction. The interaction of these complexes with calf thymus (CT-DNA) exhibited high intrinsic binding constants (Kb = 1.4 × 105–2.4 × 106 M−1), which reflected their intercalative activity toward CT-DNA. This result was also confirmed by viscosity data. Electrophoresis studies revealed that these complexes could cleave the DNA through the oxidative pathway. The in vitro anti-proliferative study establishes the anticancer potency of these compounds against human colorectal carcinoma cell line.
Scrutinizing The Status Quo: Rural Transformation and Land Tenure Security in Nigeria
Creators: name: Hosaena Ghebru
name: Fikirte Girmachew
name: Hosaena Ghebru
name: Fikirte Girmachew
Publisher: name: Unknown
Year: 2019
Subjects: subject: Food Security and Poverty
subject: International Development
subject: Food Security Group
subject: Michigan State University
subject: Innovation Lab for Food Security
subject: Nigeria

description: Despite growing consensus on the socio-economic benefits emanating from enhanced land tenure security, issues related to how best to measure it and what constitute universal indicators of tenure (in)security are poorly understood. As a result, issues of what drives tenure security are poorly understood and inconclusive. This study, thus, examines the drivers of perceived tenure insecurity in Nigeria using the Nigeria LSMS-Panel General Household Survey of 2012/13. The determinants of perceive tenure insecurity are assessed across two indicators: private (idiosyncratic) tenure risk and collective (covariate) tenure security risk. The analysis shows that perceived risks of private land dispute are higher for female-headed households, households with lower social/political connectedness, and for land parcels acquired via the traditional/customary system, in contrast to having been purchased. Private tenure risk/insecurity is also higher in communities with vibrant land market and for households that are located close to urban centers, while the opposite is the case in communities with relative ease of land access. On the other hand, collective tenure risk is lower in communities with improved economic status. Finally, signifying the need to account for intra-household dimensions in implementing land reform interventions, results from a more disaggregated analysis show that tenure security is relatively higher on female-managed plots of female-headed households, while the opposite is the case for female-managed plots of male-headed households.
Synthesis of nickel(II) complexes of isatin thiosemicarbazone derivatives: In vitro anti-cancer, DNA binding and cleavage activities
Creators: name: Amna Qasem Ali
name: Siang Guan Teoh
name: Eltayeb, Naser Eltaher
name: Ahamed, Mohamed B. Khadeer
name: Ams Abdul Majid
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Cancer
Chemistry
Earth and Environmental Sciences
Cell Biology
Biochemistry
Biophysics

description: Six new nickel(II) complexes of thiosemicarbazone Schiff base with isatin moiety [Ni(L1)2 to Ni(L6)2] were synthesized through reaction of Ni(II) with (Z)-2-(2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (L1H), (Z)-2-(5-methyl-2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (L2H), (Z)-2-(5-fluoro-2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (L3H), (Z)-N-methyl-2-(5-nitro-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (L4H), (Z)-N-methyl-2-(5-methyl-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (L5H), and (Z)-N-ethyl-2-(5-methyl-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (L6H). The structures of the Ni complexes were characterized through elemental analysis, infrared, and mass spectral data. The structure of the NiL2 complex was further characterized through single-crystal X-ray diffraction. The interaction of these complexes with calf thymus (CT-DNA) exhibited high intrinsic binding constants (Kb = 1.4 × 105 M-1 to 2.4 × 106 M-1), which reflected their intercalative activity toward CT-DNA. This result was also confirmed by viscosity data. Electrophoresis studies revealed that these complexes could cleave the DNA through the oxidative pathway. This in vitro anti-proliferative study establishes the anticancer potency of these compounds against human colorectal carcinoma cell line.
Ranging sensor fusion in LISA data processing: Treatment of ambiguities, noise, and onboard delays in LISA ranging observables
Creators: name: Reinhardt, Jan Niklas
name: Staab, Martin
name: Yamamoto, Kohei
name: Bayle, Jean-Baptiste
name: Hees, Aurélien
name: Hartwig, Olaf
name: Wiesner, Karsten
name: Shah, Sweta
name: Heinzel, Gerhard
Publisher: name: Ridge, NY : American Physical Society
Year: 2024
Subjects: subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: Interspacecraft ranging is crucial for the suppression of laser frequency noise via time-delay interferometry (TDI). So far, the effects of onboard delays and ambiguities on the Laser Interferometer Space Antenna (LISA) ranging observables were neglected in LISA modeling and data processing investigations. In reality, onboard delays cause offsets and timestamping delays in the LISA measurements, and pseudorandom noise (PRN) ranging is ambiguous, as it determines only the range up to an integer multiple of the PRN code length. In this article, we identify the four LISA ranging observables: PRN ranging, the sideband beat notes at the interspacecraft interferometer, TDI ranging, and ground-based observations. We derive their observation equations in the presence of onboard delays, noise, and ambiguities. We then propose a three-stage ranging sensor fusion to combine these observables in order to gain accurate and precise ranging estimates. We propose to calibrate the onboard delays on ground and to compensate the associated offsets and timestamping delays in an initial data treatment (stage 1). We identify the ranging-related routines, which need to run continuously during operation (stage 2) and implement them numerically. Essentially, this involves the reduction of ranging noise, for which we develop a Kalman filter combining the PRN ranging and the sideband beat notes. We further implement cross-checks for the PRN ranging ambiguities and offsets (stage 3). We show that both ground-based observations and TDI ranging can be used to resolve the PRN ranging ambiguities. Moreover, we apply TDI ranging to estimate the PRN ranging offsets.
Isolation of chlorogenic acid from Mutellina purpurea L. herb using high-performance counter-current chromatography
Creators: name: Sieniawska, Elwira
name: Skalicka-Woźniak, Krystyna
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Engineering
subject: Biochemistry

description: The aim of the study was to explore proper isolation conditions of chlorogenic acid from the herb of Mutelina purpurea L. – a new source of this bioactive molecule. The accelerated solvent extraction (ASE) with 40% aqueous solution of methanol combined with high-performance counter-current chromatography (HPCCC) was utilised for the efficient extraction and the separation of chlorogenic acid from the M. purpurea herb in less than 30 min. The structure of the obtained compound was confirmed by mass spectrometry and NMR analysis. The preparative HPCCC was performed using the mixture of ethyl acetate, butanol and water (4:1:5, v/v/v) in the reverse-phase mode. The chlorogenic acid was isolated from this herb for the first time, yielding 96% purity. The ASE with 40% methanol combined with HPCCC separation was proven to be a useful tool for quick and efficient isolation of chlorogenic acid from M. purpurea.
The Effects of Feed Costs and Increased Energy Needs on Broiler Farm Productivity: A Dynamic Programming Approach
Creators: name: Padilla, Samantha
name: Lenis Saweda O. Liverpool-Tasie
name: Myers, Robert J.
name: Padilla, Samantha
name: Lenis Saweda O. Liverpool-Tasie
name: Myers, Robert J.
Publisher: name: Unknown
Year: 2019
Subjects: subject: Food Security and Poverty
subject: International Development
subject: Food Security Group
subject: Michigan State University
subject: Innovation Lab for Food Security
subject: Nigeria

description: While Africa has seen a rapid growth of commercial livestock enterprises with its food systems transformation, little is known about their viability. We explore the profitability of commercial poultry enterprises facing rising input costs and increasing energy needs due to the adoption of climate mitigating technologies in Nigeria. Using a cross-sectional dataset and a one-year weekly panel of farm inputs and prices, we employ a discrete time, discrete control and state space dynamic programming model disaggregated by farm size to determine the source of economies of scale among commercial poultry farms. In the presence of high feed costs and increased energy needs, the optimal decision for medium sized farms is to sell and exit the industry. However, it remains profitable for large farms to stay in the sector. The findings are robust to various alternative model assumptions and specifications. They indicate that broiler farms need larger stock sizes to withstand negative input price shocks and expand energy consumption in the face of volatile and hotter temperatures. The sensitivity of the poultry industry to the feed prices is a major threat to the growth and survival of farms and highlight the importance of developing risk management mechanisms to stabilize prices.
Total Synthesis of an Experimental Antitubercular Drug CDRI-830
Creators: name: Pailla, Uma Reddy
name: Arava, Veera Reddy
name: L. K. Ravindranath
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Molecular Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Microbiology
subject: FOS: Biological sciences

description: The triarylmethane antituberculosis drug CDRI-830 is synthesized. The triarylmethane derivative 4 is prepared from ether 6 by a rearrangement process. The total synthesis of the drug CDRI-830 is achieved in a good overall yield of 35% from a simple thiophene derivative 8.
Cleavage of Diethyl Chromonyl α-Aminophosponate with Nitrogen and Carbon Nucleophiles: A Synthetic Approach and Biological Evaluations of a Series of Novel Azoles, Azines, and Azepines Containing α-Aminophosphonate and Phosphonate Groups
Creators: name: Ali, Tarik E.
name: Abdel-Aziz, Salah A.
name: Somaya M. El-Edfawy
name: El-Hossain A. Mohamed
name: Somaia M. Abdel-Kariem
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 60506 Virology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Physiology
subject: Biochemistry

description: A convenient synthetic approach leading to a series of novel substituted azoles, azines, and azepines linked to the α-aminophosphonate moiety was achieved. The methodology depends on ring opening and ring closure (RORC) of the chromone ring of diethyl chromonyl α-aminophosphonate 1 via its reaction with nitrogen nucleophiles such as primary amines and 1,2-, 1,3-, and 1,4-bi-nucleophiles in ethanolic sodium ethoxide. Also, treatment of compound 1 with some acyclic and cyclic active methylene compounds under the same reaction conditions afforded interesting novel isolated and fused pyridine systems bearing phosphonate groups at the α-position. The screening of antimicrobial activity for the synthesized compounds indicates that connection of pyrazole, oxazepine, and benzodiazepine rings with α-aminophosphonate moiety exhibited good antimicrobial effects. Also, evaluation of their antioxidant properties shows that the compounds having 1,5-benzoxazepinyl and 1,5-benzodiazepinyl units in combination with α-aminophosphonic diester moiety are the most powerful antioxidant agents.
Heisenberg versus the Covariant String
Creators: name: Dragon, Norbert
name: Oppermann, Florian
Publisher: name: New York, NY : Springer Science + Business Media B.V.
Year: 2024
Subjects: subject: Constrained system
subject: Continuous spectrum
subject: Covariant string
subject: Heisenberg algebra
subject: Mass shell condition
subject: Stone-von Neumann theorem
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: A Poincaré multiplet of mass eigenstates (P2- m2) Ψ = 0 cannot be a subspace of a space with a D-vector position operator X= (X, ⋯ XD-1) : the Heisenberg algebra [Pm, Xn] = i δmn implies by a simple argument that each Poincaré multiplet of definite mass vanishes. The same conclusion follows from the Stone-von Neumann theorem. In a quantum theory the constraint of an absolutely continuous spectrum to a lower dimensional submanifold yields zero even if Dirac’s treatment of the corresponding classical constraint defines a symplectic submanifold with a consistent corresponding quantum model. Its Hilbert space is not a subspace of the unconstrained theory. Hence the operator relations of the unconstrained model need not carry over to the constrained model. Our argument excludes quantized worldline models of relativistic particles and the physical states of the covariant quantum string. We correct misconceptions about the generators of Lorentz transformations acting on particles.
title: Ηγεσία, διαχείριση συγκρούσεων και ομαδική εργασιακή απόδοση στις δημόσιες δομές υγείας
title: Leadership, conflict management and teamwork performance in public health structures
titleType: AlternativeTitle
Creators: name: Βαλαβάνη, Νεφέλη
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Στυλ ηγεσίας
Διαχείριση συγκρούσεων
Στρατηγικές
Απόδοση ομαδικής εργασίας
Οργανισμοί υγείας
Δημόσια υγεία
Εργασιακή απόδοση
Ηγεσία

description: Η παρούσα εργασία αφορά στη διερεύνηση της μεταξύ των εφαρμοζόμενων στυλ ηγεσίας, των στρατηγικών διαχείρισης συγκρούσεων και της απόδοσης της ομαδικής εργασίας σε δομές δημόσιας υγείας. Για το σκοπό αυτό εκτός της θεωρητικής αποτύπωσης των χαρακτηριστικών της σύνδεσης των παραπάνω στοιχείων, εφαρμόζεται ποσοτική ανάλυση με τη χρήση ερευνητικού εργαλείου κλειστού τύπου σε δείγμα 140 επαγγελματικών δημόσιας υγείας. Τα αποτελέσματα αναδεικνύουν μέτρια επίπεδα χρήσης των μετασχηματιστικών και συναλλακτικών πρακτικών ηγεσίας μεταξύ των ηγετών στον τομέα της υγείας, με την εφαρμογή του στιλ της παθητικής ηγεσίας να είναι σχετικά υψηλότερη. Η απόδοση των εργασιακών ομάδων κρίθηκε γενικά υψηλή, ιδιαίτερα σε όρους παραγωγικότητας και επίτευξη στόχων, ενώ οι στρατηγικές διαχείρισης συγκρούσεων ποικίλλουν. Παράλληλα, προκύπτουν θετικές συσχετίσεις μεταξύ της μετασχηματιστικής και συναλλακτικής ηγεσίας και της ομαδικής εργασιακής απόδοσης, ενώ επιπρόσθετα στρατηγικές της εξομάλυνσης και της συνεργασίας στη διαδικασία της διαχείρισης των οργανωσιακών συγκρούσεων επηρεάζουν επίσης θετικά την απόδοση των εργασιακών ομάδων. Βάσει των παραπάνω κρίνεται ότι δημιουργία οργανωσιακής κουλτούρας που εστιάζει στην ελαχιστοποίηση των συγκρούσεων και στη βελτίωση της απόδοσης των ομάδων εργασίας αποτελεί κρίσιμο παράγοντα για την αποτελεσματικότητα της ηγεσίας.
Perceived Tenure (In)Security in the Era of Rural Transformation Gender-Disaggregated Analysis from Mozambique
Creators: name: Hosaena Ghebru
name: Fikirte Girmachew
name: Hosaena Ghebru
name: Fikirte Girmachew
Publisher: name: Unknown
Year: 2019
Subjects: subject: Food Security and Poverty
subject: International Development
subject: Food Security Group
subject: Michigan State University
subject: Innovation Lab for Food Security
subject: Mozambique

description: This study examines the drivers of tenure insecurity in Mozambique using data from the National Agricultural Survey (TIA) 2014 as well as a follow-up supplemental survey with detailed land tenure gender-disaggregated data from three groups: namely, principal male, principal female, and female spouses. Perceived risk of land loss (collective tenure risk) and perceived risk of a private land dispute (individual tenure risk) are used to measure land tenure insecurity. The empirical findings reveal, overall, collective tenure risks are the real threat to women’s tenure security while individual tenure risks (ownership, inheritance, border disputes, etc.) are more of a threat to the tenure security of men. However, a more gender-disaggregated analysis reveals that individual tenure risk is higher among female spouses as compared to male heads within the same household. Moreover, perceived risk of land loss is higher among non-indigenous male heads while female spouses who have no control over family land are more likely to have higher perceived tenure insecurity. Results also show that landrelated legal awareness seems to be more significant in dictating the (positively) perceived tenure security of women as compared to their male counterparts. Generally, tenure insecurity for female spouses seem to be associated with the emergence of land markets while relative land scarcity in a given community dictates tenure insecurity of the principal female (female heads). Hence, the empirical findings reinforce the need to complement ongoing efforts to enhance tenure security at the household and community level with gender-tailored/targeted programs that take into account the intra-household dimension of addressing issues of land tenure security.
title: Hong Kong : protestations, politique et identité (Colloque)
Publisher: name: Fondation Maison des sciences de l'homme
Year: 2019

description: HONG KONG, cette « perle orientale » considérée depuis longtemps   comme une ville de commerce par excellence, connaît des protestations   politiques de grande envergure depuis l’été 2019. Le monde entier en est   témoin à travers les images diffusées abondamment dans les médias et la   presse internationale. De nombreux signes à l’intérieur et à   l’extérieur de la Chine montrent que cet immense pays et ses relations   avec le monde entrent dans une nouvelle période de grande incertitude.   En ce moment historique, ce qui se passe à Hong Kong, ville symbolique   de la modernité en Chine, nous livre certains messages pour l’avenir de   Hong Kong et de la Chine.  Quels facteurs sont à l’origine de   ces mouvements protestataires ? Quel en sera l’impact dans la formation   d’une nouvelle identité hongkongaise ? Que pouvons-nous attendre de
Highly Efficient and Practical Method for Synthesis of 2,2′-Azino-Bis(3-Ethyl-benzothiazoline-6-Sulfonic Acid) (ABTS) and Its Diammonium Salt
Creators: name: Junmin Chen
name: Xiaomeng Zhou
name: Tangjun Yuan
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Pharmacology
Biological Sciences
Chemistry
Biotechnology
Cell Biology
Physics
Biochemistry
Biophysics

description: A highly efficient and practical protocol for synthesis of 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and its diammonium salt has been carried out by six steps. On comparison of the traditional methods, the present protocol has many advantages including mild reaction conditions, excellent product yields, shorter reaction steps, and no hazardous reagents. Moreover, the present protocol also provides an easy scaling and separation method.
title: Λειτουργικά συστατικά τροφίμων: Εφαρμογές σε προϊόντα ελληνικής διατροφής
title: Functional food ingredients: Applications in Greek food products
titleType: AlternativeTitle
Creators: name: Μπουροπούλου, Γεωργία
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Λειτουργικά συστατικά τροφίμων
Ελληνικά προϊόντα διατροφής
Αντιοξειδωτικά
Βιταμίνες
Προβιοτικά
Πρεβιοτικά

description: Η παρούσα πτυχιακή διερευνά την ενσωμάτωση λειτουργικών συστατικών τροφίμων στα σύγχρονα ελληνικά προϊόντα διατροφής, εστιάζοντας στις εφαρμογές τους στους χυμούς και τα φυτικά ροφήματα, τα δημητριακά, το γάλα και τα γαλακτοκομικά προϊόντα, τα λίπη και έλαια, καθώς και το κρέας και τα αυγά. Η πτυχιακή ξεκινά με μια εισαγωγή που περιγράφει τον σκοπό της πτυχιακής, τη δομή της και τη μεθοδολογία άντλησης δευτερογενών στοιχείων. Το θεωρητικό υπόβαθρο εμβαθύνει στους ορισμούς των λειτουργικών συστατικών τροφίμων και παρέχει μια λεπτομερή επισκόπηση επιλεγμένων συστατικών, όπως L-ασκορβικό οξύ, βιταμίνες του συμπλέγματος Β, καλσιφερόλη, α-τοκοφερόλη, ρετινόλη, φυτοστερόλες, προβιοτικά βακτήρια όπως Bifidobacterium bifidum, φυτικές ίνες, Ω-3 λιπαρά οξέα, σελήνιο και συγκεκριμένες βιοδραστικές ενώσεις όπως η κροκίνη, η σαφρανάλη και η κροκετίνη. Συζητούνται επίσης νομικές πτυχές που αφορούν την ενσωμάτωση αυτών των συστατικών σε προϊόντα διατροφής. Ο πυρήνας της πτυχιακής βρίσκεται στο Κεφάλαιο 3, όπου οι εφαρμογές των λειτουργικών συστατικών τροφίμων στα ελληνικά προϊόντα διατροφής αναλύονται σε διάφορες κατηγορίες. Γίνεται αναφορά σε γνωστές εμπορικές μάρκες χυμών και φυτικών ροφημάτων, προϊόντων δημητριακών, γάλακτος και γαλακτοκομικών προϊόντων, λιπών και τα ελαίων, καθώς και κρέατος τα οποία περιέχουν λειτουργικά συστατικά είτε από τη φύση τους, είτε έπειτα από εμπλουτισμό. Το Κεφάλαιο 4 περιγράφει λεπτομερώς τις μεθόδους που χρησιμοποιούνται για την ενσωμάτωση αυτών των συστατικών στα προϊόντα. Τα επόμενα κεφάλαια, 5 και 6, παρουσιάζουν τα αποτελέσματα και τις συζητήσεις που προέκυψαν από την ανάλυση, οδηγώντας σε ολοκληρωμένα συμπεράσματα. Η μελέτη στοχεύει να προσφέρει πολύτιμες γνώσεις για την ενίσχυση του διατροφικού προφίλ και των οφελών για την υγεία των σύγχρονων ελληνικών προϊόντων διατροφής μέσω της στρατηγικής ενσωμάτωσης λειτουργικών συστατικών τροφίμων. Αυτή η έρευνα δεν είναι σημαντική μόνο από ακαδημαϊκής, αλλά και από πρακτικής άποψης για την ελληνική βιομηχανία τροφίμων, προωθώντας την καινοτομία και τη βελτίωση της ποιότητας διατροφής των καταναλωτών.
Impacts of Aerosol Aging on Laser Desorption/Ionization in Single-Particle Mass Spectrometers
Creators: name: Hatch, Lindsay E.
name: Pratt, Kerri A.
name: J. Alex Huffman
name: Jimenez, Jose L.
name: Prather, Kimberly A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Biotechnology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Astronomy, Astrophysics, Space Science
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Microbiology
subject: Engineering
subject: Biochemistry

description: Single-particle mass spectrometry (SPMS) has been widely used for characterizing the chemical mixing state of ambient aerosol particles. However, processes occurring during particle ablation and ionization can influence the mass spectra produced by these instruments. These effects remain poorly characterized for complex atmospheric particles. During the 2005 Study of Organic Aerosols in Riverside (SOAR), a thermodenuder was used to evaporate the more volatile aerosol species in sequential temperature steps up to 230°C; the residual aerosol particles were sampled by an aerosol mass spectrometer (AMS) and a single-particle aerosol time-of-flight mass spectrometer (ATOFMS). Removal of the secondary species (e.g., ammonium nitrate/sulfate) through heating permitted assessment of the change in ionization patterns as the composition changed for a given particle type. It was observed that a coating of secondary species can reduce the ionization efficiency by changing the degree of laser absorption or particle ablation, which significantly impacted the measured ion peak areas. Nonvolatile aerosol components were used as pseudo-internal standards (or “reference components”) to correct for this LDI effect. Such corrected ATOFMS ion peak areas correlated well with the AMS measurements of the same species up to 142°C. This work demonstrates the potential to accurately relate SPMS peak areas to the mass of specific aerosol components.Copyright 2014 American Association for Aerosol Research
title: Μετανάστευτική πολιτική: Η ένταξη και νομιμοποίηση των προσφύγων και των μεταναστων στην Ελλάδα και ο ανασχεδιασμός της πλατφόρμας του υπουργείου μετανάστευσης και ασύλου
title: Immigration policy the integration and legalization of refugees and immigrants in Greece and the redesign of the ministry of migration and asylums platform
titleType: AlternativeTitle
Creators: name: Γαβαλά-Τσουκάτου, Μαρία
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2023
Subjects: subject: Μετανάστευση
subject: Μεταναστευτική πολιτική
subject: Ελλάδα--Μεταναστευτική πολιτική
subject: Πληροφορικό σύστημα
subject: Μεταναστευτικά ρεύματα
subject: Νομιμοποίηση προσφύγων και μεταναστών
subject: Ένταξη προσφύγων και μεταναστών
subject: Μεταναστευτική πολιτική

description: Το μεταναστευτικό ζήτημα είναι ένα ζήτημα που ταλανίζει την χώρα μας , ιδίως τα τελευταία χρόνια. Η αλλεπάλληλη και συνεχώς αυξανόμενη εισροή μεταναστευτικών ρευμάτων στην ελληνική επικράτεια σε συνδυασμό με την ανεπάρκεια του υπάρχοντος συστήματος και τα ελάχιστα διαθέσιμα μέσα , καθιστούν δύσκολη εάν όχι αδύνατη την διαχείριση αυτών των ανθρώπων. Το κεντρικό ερώτημα γύρω από την δόμηση της παρούσας εργασίας λοιπόν είναι διττό και έγκειται αφενός στην διερεύνηση των λόγων για των οποίων η Ελλάδα επιλέγεται ή και καταλήγει να είναι η χώρα που λαμβάνει το μεγαλύτερο αριθμό εισροών μεταναστευτικών ρευμάτων και αφετέρου στην ανάδειξη των ποσοστών επιτυχίας που έχει αναφορικά με την ενσωμάτωση και νομιμοποίηση τους. Με γνώμονα λοιπόν αυτά η παρούσα εργασία δομήθηκε γύρω από τα παρακάτω ερωτήματα , τα οποία εν συνεχεία θα αναλυθούν περεταίρω: α) Εάν παρατηρείται μια κοινή γραμμή μεταξύ του συστήματος που ισχύει ή θα έπρεπε να ισχύει σε επίπεδο Ε.Ε , σε σχέση με την Ελλάδα, β) ποια είναι τα προβλήματα που καθιστούν το Ελληνικό σύστημα δυσλειτουργικό ως προς την απόδοση εγγράφων των ανθρώπων αυτών , τις παρεχόμενες υπηρεσίες αλλά και την ενσωμάτωση τους στην κοινωνία και γ) πως μέσα από τον ανασχεδιασμό του υπάρχοντος μοντέλου για την νομιμοποίηση αυτών των προσώπων θα υπάρξουν βελτιώσεις. Η παρούσα εργασία λοιπόν μέσα από την παρουσίαση της ακολουθούμενης μεταναστευτικής πολιτικής και την ανάδειξη των προβλημάτων που αντιμετωπίζει η χώρα μας , στοχεύει στην προβολή των αδυναμιών του ισχύοντος πληροφοριακού μας συστήματος και της κοινωνίας εν γένει. Αδυναμίες που έγκειται όχι μόνο σε σχέση με την απονομή των απαραίτητων νομιμοποιητικών εγγράφων για την νόμιμη παραμονή των πολιτών τρίτων χωρών στην Ελλάδα αλλά και σε επίπεδο ενσωμάτωσης αυτών στην κοινωνία.
International collaboration as a common approach to improve the FAIRness of non-numeric/ qualitative research data
Creators: name: Mozygemba, Kati
name: Betancort Cabrera, Noemi
Publisher: name: Zenodo
Year: 2024

description: The future of sharing and reusing qualitative research materials will be shaped by technological innovations, ethical considerations, privacy and data security issues, collaborative efforts, and an increased focus on improving the rigor and applicability  of findings derived from existing non-numeric/qualitative datasets.

Due to the sensitivity and comprehensiveness of the data, the integration of (AI-based) technology in data curation, data sharing and data analysis workflows needs to be carefully addressed, as well as issues of interdisciplinary approaches. Furthermore, researchers from different disciplines will be interested in using qualitative data, and vice versa, qualitative researchers will be interested in using data from other methodological backgrounds that lend themselves to the application of qualitative analysis.

In the face of these developments and challenges, collaboration between data infrastructures with expertise in the curation and provision of qualitative data is key. Networks such as QualidataNet, a community-centered federated network of RDCs, seek to share and discuss common solutions for harmonization and standardization where possible. Its focus is to provide a single point of access to qualitative datasets from different data providers and to promote the sharing and reuse of qualitative data in line with the FAIR Data Principles.

QualidataNet is part of the Consortium for Social, Behavioral, Educational and Economic Sciences (KonsortSWD) at the National Research Data Infrastructure (NFDI) in Germany. It coordinates the international cooperation within the DDI via the DDI-CDI Subgroup "Non-Numeric, Non-Code Datums", which aims at a standardized and comprehensive metadata description of data objects to enable cross domain integration.

We will present the current work, future steps and plans of this international effort: In addition, we would like to continue exploring opportunities for international collaboration and exchange, and invite for participation with the goal of shaping FAIR's ways of processing, archiving, and reusing qualitative data objects.
D4.8 - Ontology ecosystem knowledge graph, second version
Creators: name: Breslin, John
name: Yang, Lan
Publisher: name: Zenodo
Year: 2023
Subjects: Ontology
Knowledge base
Knowledge graph

description: This document provides a comprehensive overview of the OntoCommons project's knowledge base, which is developed through the use of a designated platform called OCEANS (OntoCommons Collaborative Editing and Authoring Knowledge graphs), used to record the knowledge generated in the project in a machine-readable format and visualized through knowledge graphs. The OCEANS platform is built on top of an open-source collaborative environment supporting RDF/OWL known as WebProtégé, which has been customized to better suit the needs of OntoCommons while still retaining most of its features.The primary objective of creating the knowledge base is to ensure that all the information regarding the Ontology Commons Ecosystem (OCES) Toolkit generated within Work Package 4 (WP4) is encoded into machine-readable knowledge graphs that describe the OCES Toolkit and beyond. This will enable researchers and practitioners from diverse backgrounds to collaborate and contribute to the knowledge base, thereby enriching the OntoCommons project.The first version of the ontology ecosystem knowledge graph accomplished many valuable outcomes. For instance, it defined the ontology ecosystem knowledge base and knowledge graph, established the content model of the ontology ecosystem knowledge base, analyzed the requirements for the collaborative editing and authoring platform, created the architecture of OCEANS, and generated the first version of the ontology ecosystem knowledge base and knowledge graphs. In the second version, the team focused on restructuring the knowledge base. Specifically, they followed an upper-level ontology, the information artefact ontology, to regroup and classify the information artefacts used in the OCES Toolkit. Additionally, the knowledge graph of the second version was visualized through SousLeSens to enhance the project's cutting-edge nature and ensure it remains at the forefront of the field. This iterative process of refining and enhancing the ontologyecosystem knowledge graph is a continuous effort to improve its functionality and relevance.
Cleavage of Diethyl Chromonyl α -Aminophosphonate with Nitrogen and Carbon Nucleophiles: A Synthetic Approach and Biological Evaluations of a Series of Novel Azoles, Azines and Azepines Containing α -Amino-Phosphona
Creators: name: Ali, Tarik E.
name: Abdel-Aziz, Salah A.
name: Somaya M. El-Edfawy
name: El-Hossain A. Mohamed
name: Somaia M. Abdel-Kariem
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 60506 Virology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Physiology
subject: Biochemistry

description: A convenient synthetic approach leading to synthesize a series of novel substituted azoles, azines and azepines linked to α -aminophosphonate moiety was achieved. The methodology depends on ring-opening and ring-closure (RORC) of chromone ring of diethyl chromonyl α -aminophosphonate 1via its reaction with nitrogen nucleophiles such as primary amines, 1,2-, 1,3- and 1,4-bi-nucleophiles in ethanolic sodium ethoxide. Also, treatment of compound 1 with some acyclic and cyclic active methylene compounds under the same reaction conditions afforded interesting novel isolated and fused pyridine systems bearing phosphonate groups at α -position. The screening of antimicrobial activity for the synthesized compounds indicates that connection of pyrazole, oxazepine and benzodiazepine rings with α -aminophosphonate moiety exhibited good antimicrobial effects. Also, evaluation of their antioxidant properties exemplifies that the compounds having 1,5-benzoxazepinyl and 1,5-benzodiazepinyl units in combination with α-amino-phosphonic diester moiety are the most powerful antioxidant agents.
Genetic determinants of paclitaxel-induced peripheral neuropathy: a review of current literature
Creators: name: Sivadas, Swathi Krishna
name: Das, Aiswarya
name: Vijayakumar, Nandana
name: Shaji, Nandana
name: Mangalath, Sabitha
name: Pavithran, Keechilat
name: Biswas, Lalitha
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Paclitaxel is a widely used chemotherapeutic agent recognized for its efficacy against various malignancies. However, its clinical utility is often limited by paclitaxel-induced peripheral neuropathy (PIPN), a dose-dependent and debilitating side effect that significantly impacts patient quality of life. Genetic predisposition plays a critical role in individual susceptibility to PIPN, influencing both drug metabolism and neuropathic responses. This review examines the genetic basis of PIPN, focusing on polymorphisms in key genes associated with paclitaxel metabolism, transport, neuroinflammation, and neuronal signaling. Variants in CYP2C8, CYP3A4, and CYP2C9 affect drug metabolism, while polymorphisms in ABCB1 and SLCO1B1 influence drug transport. Genes involved in neuroinflammatory pathways (TNF-α, IL-6, IL-1β), peripheral nerve integrity (MAPT, TUBB2), and neuronal signaling (SCN9A) have also been implicated in PIPN susceptibility. Understanding genetic contributions to PIPN is essential for unraveling its pathophysiology and developing targeted interventions. Integrating genetic markers into clinical practice can facilitate personalized treatment strategies, minimizing PIPN risk and enhancing therapeutic outcomes. Further studies are needed to validate these findings across diverse populations and uncover novel genetic determinants.
A Highly Efficient and Practical Method for Synthesis of 2,2′-Azino-bis(3-ethyl-benzothiazoline-6-sulphonic Acid) and Its Diammonium Salt (ABTS)
Creators: name: Junmin Chen
name: Xiaomeng Zhou
name: Tangjun Yuan
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Pharmacology
Biological Sciences
Chemistry
Biotechnology
Cell Biology
Physics
Biochemistry
Biophysics

description: A highly efficient and practical protocol for synthesis of 2, 2′-azino-bis(3-ethylbenzothiazoline-6-sulfonicacid) and its diammonium salt (ABTS) has been carried out by six steps. On comparison of the traditional methods, the present protocol has many advantages including mild reaction conditions, excellent product yields, shorter reaction steps, and no hazardous reagents. Moreover, the present protocol also provides an easy scale-up and separation method.
Segmentation analysis of cleared mouse gastruloids imaged with light-sheet microscopy
Creators: name: Mossige, Joachim
name: Angheluta-Bauer, Luiza
name: Ho, Richard David Jun-Geet
name: Jensenius, Alexander Refsum
name: Ponomartcev, Sergei
name: Krauss, Stefan
name: Wilson, Steven Haakon Ray
name: Kjos, Ingrid
name: Røberg-Larsen, Hanne
name: Hu, Xian
name: Dysthe, Dag Kristian
Publisher: name: OSF
Year: 2025
Subjects: Cell
Gastrulation
Gastruloid
Light sheet microscopy
Microscopy
Simulation
Stem cell

description: Segmentation data and codes for the gastruloid project
Impacts of Aerosol Aging on Laser Desorption/Ionization in Single-Particle Mass Spectrometers
Creators: name: Hatch, Lindsay E.
name: Pratt, Kerri A.
name: J. Alex Huffman
name: Jimenez, Jose L.
name: Prather, Kimberly A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Biotechnology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Astronomy, Astrophysics, Space Science
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Microbiology
subject: Engineering
subject: Biochemistry

description: Single-particle mass spectrometry (SPMS) has been widely used for characterizing the chemical mixing state of ambient aerosol particles. However, processes occurring during particle ablation and ionization can influence the mass spectra produced by these instruments. These effects remain poorly characterized for complex atmospheric particles. During the 2005 Study of Organic Aerosols in Riverside (SOAR), a thermodenuder was used to evaporate the more volatile aerosol species in sequential temperature steps up to 230 ˚C; the residual aerosol particles were sampled by an aerosol mass spectrometer (AMS) and a single-particle aerosol time-of-flight mass spectrometer (ATOFMS). Removal of the secondary species (e.g., ammonium nitrate/sulfate) through heating permitted assessment of the change in ionization patterns as the composition changed for a given particle type. It was observed that a coating of secondary species can reduce the ionization efficiency by changing the degree of laser absorption or particle ablation, which significantly impacted the measured ion peak areas. Non-volatile aerosol components were used as pseudo-internal standards (or “reference components”) to correct for this LDI effect. Such corrected ATOFMS ion peak areas correlated well with the AMS measurements of the same species up to 142 ˚C. This work demonstrates the potential to accurately relate SPMS peak areas to the mass of specific aerosol components.
Cleavage of Diethyl Chromonyl α-Aminophosponate with Nitrogen and Carbon Nucleophiles: A Synthetic Approach and Biological Evaluations of a Series of Novel Azoles, Azines, and Azepines Containing α-Aminophosphonate
Creators: name: Ali, Tarik E.
name: Abdel-Aziz, Salah A.
name: Somaya M. El-Edfawy
name: El-Hossain A. Mohamed
name: Somaia M. Abdel-Kariem
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 60506 Virology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Physiology
subject: Biochemistry

description: A convenient synthetic approach leading to a series of novel substituted azoles, azines, and azepines linked to the α-aminophosphonate moiety was achieved. The methodology depends on ring opening and ring closure (RORC) of the chromone ring of diethyl chromonyl α-aminophosphonate 1 via its reaction with nitrogen nucleophiles such as primary amines and 1,2-, 1,3-, and 1,4-bi-nucleophiles in ethanolic sodium ethoxide. Also, treatment of compound 1 with some acyclic and cyclic active methylene compounds under the same reaction conditions afforded interesting novel isolated and fused pyridine systems bearing phosphonate groups at the α-position. The screening of antimicrobial activity for the synthesized compounds indicates that connection of pyrazole, oxazepine, and benzodiazepine rings with α-aminophosphonate moiety exhibited good antimicrobial effects. Also, evaluation of their antioxidant properties shows that the compounds having 1,5-benzoxazepinyl and 1,5-benzodiazepinyl units in combination with α-aminophosphonic diester moiety are the most powerful antioxidant agents.