cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids
Creators: name: Sagawa, Takuya
name: Kako, Noritaka
name: Nakaya, Masatoshi
name: Izumi, Takaaki
name: Takeda, Kosuke
name: Iijima, Kazutoshi
name: Hashizume, Mineo
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Molecular Biology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Marine Biology

description: Recently, fabrication of organic-inorganic hybrid biomedical materials using biomimetic mineralization processes has received attention because it proceeds under mild conditions and biocompatible inorganic components are incorporated in the resulting hybrids. In the present study, the preparation of anionic polyelectrolyte-apatite hybrids, having potential as a biomedical material, in simulated body fluids (SBFs) was performed. Anionic polyelectrolytes such as heparin, poly(4-styrene sulfonate) (PSS), or poly(vinyl sulfate) (PVS) were added to SBFs and incubated to induce nucleation of hydroxyapatite, which resulted in the formation of anionic polyelectrolyte-apatite hybrids. Physical characterization of the resulting deposits in SBFs using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), FT-IR spectroscopy, and X-ray diffraction (XRD) revealed that the polyelectrolyte concentration affected the yield of the resulting deposits. It seemed that the reaction condition affected the apatite nucleation process in SBFs. Effect of chemical structures and concentrations of anionic polyelectrolytes on hybrid formation is discussed.
Cassia ligustrina Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Cassia
Cassia ligustrina

description: Cassia ligustrina, spec. nov.
 14. Cassia foliolis septemjugatis lanceolatis: extimis minoribus, glandula baseos petiolorum. Hort. cliff. 199. Hort. ups. 100. Gron. virg. 47. Roy. lugdb. 467.
 Cassia ligustri folio. Plum. spec. 10. Dill. elth. 350. t. 269. f.338.
 Cassia bahamensis, pinnis foliorum mucronatis angustis, calyce floris non reflexo. Mart. cent. 21. t.21.
 Habitat in Virginia , Bahama . ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 378, DOI: 10.5281/zenodo.3931989
The Hybrid Transmission Grid Architecture: Benefits in Nodal Pricing
Creators: name: Hotz, Matthias
name: Utschick, Wolfgang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: Recently, we proposed a capacity expansion approach for transmission grids that combines the upgrade of transmission capacity with a transition in system structure to improve grid operation. The key to this concept is a particular hybrid AC/DC transmission grid architecture, which is obtained by uprating selected AC lines via a conversion to HVDC. We have shown that this system structure improves optimal power flow (OPF) solvability and that it can reduce the total generation costs. In this work, we study the benefits of this hybrid architecture in the context of a deregulated electricity market. We propose an efficient and accurate nodal pricing method based on locational marginal prices (LMPs) that utilizes a second-order cone relaxation of the OPF problem. Applicability of this method requires exactness of the relaxation, which is difficult to obtain for conventional meshed AC transmission grids. We prove that the hybrid architecture ensures applicability if the LMPs do not coincide with certain pathological price profiles, which are shown to be unlikely under normal operating conditions. Using this nodal pricing method, we demonstrate that upgrading to the hybrid architecture can not only increase the effective transmission capacity but also reduce the separation of nodal markets and improve the utilization of generation.
description: IEEE Transactions on Power Systems
What is the vow of a student? -- short answers from Acharya Sthaneshwar
Creators: name: Timalsina, Staneshwar
Publisher: name: Zenodo
Year: 2024
Subjects: Tantric philosophy
anava upaya
yantra
amnaya
Shiva
Shaiva
vimarsha-foundation
consciousness
mahadeva
Vasugupta
Sarvamnaya
tripura
Durga
Kaula
Abhinavagupta
Shiva Sutra
Kula
saivadvaita
vedanta
Mahakali
Tantra
Chandi
Kali
advaita vedanta
Bhairava
shambhava
timalsina
Spanda
Kashmir Shaivism
krama
Saundaryalahari
Tripura Rahasya
Tripurasundari
Camunda
agama
Devi Mahatmya
sarvamnaya
Guhyakālī
shakti
tantraloka
Divine Mother
sarvamnaya-oral-tradition-archive
trika
sthaneshwar timalsina
Īśāna
Mālinīvijayottaratantra
shakta upāya
Kubjika
Sadāśiva

description: Acharya Dr. Sthaneshwar Timalsina is an esteemed traditionally consecrated teacher of Shaiva-Shakta Hindu Tantra. He is also the Endowed Chair of Indic Studies in New York, U.S.A. at Stony Brook University's College of Arts & Sciences in the Department of Asian & Asian-American Studies. Acharya Sthaneshwar founded Vimarsha Foundation as a modern school (gurukula) for teaching and reflecting on the ancient wisdom of r̥ṣis and siddhas. Through Vimarsha Foundation, a non-profit organization, Acharya Sthaneshwar teaches shastra and sādhanā to students of all backgrounds. The Vimarsha Foundation hosts free semester length courses on classic texts of the Tantric Tradition and offers many more free video and written teachings. Visit our website to learn more: https://www.vimarshafoundation.org/

#hinduism #shishya #gurushishya

Original YouTube video: https://www.youtube.com/watch?v=MvjzUzaT09s

This presentation is part of the Sarvāmnāya Oral Tradition Archive.
Vimarsha Foundation. (2025). The Sarvāmnāya Oral Tradition Archive [Data set]. Zenodo. https://doi.org/10.5281/zenodo.15188107
Estimates for simple random walks on fundamental groups of surfaces
Creators: name: Bartholdi, Laurent
name: Cantat, Serge
name: Ceccherini-Silberstein, Tullio
name: de la Harpe, Pierre
Publisher: name: arXiv
Year: 2006
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 60J15, 20F32

description: Numerical estimates are given for the spectral radius of simple random walks on Cayley graphs. Emphasis is on the case of the fundamental group of a closed surface, for the usual system of generators.
description: 22 pages, 5 figures, amstex
Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources
Creators: name: Wadthanakul, Jatsada
name: Sriprapha, Phanrawee
name: Boothrawong, Narongdech
name: Chokethawai, Komsanti
name: Randorn, Chamnan
name: Boontakam, Waraporn
name: Chandet, Nopakarn
name: Thongkorn, Kriangkrai
name: Rujijanagul, Gobwute
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Normally, hydroxyapatite (HAp) ceramics have no antimicrobial activity. Therefore, the development of the HAp with enhanced antimicrobial characteristics is essential for the prevention of infections associated with medical implants. In this research article, porous hydroxyapatite (HAp) ceramics were synthesized via a simple thermal decomposition of bovine bone. All synthesized samples contained the main phase of HAp. However, beta tricalcium phosphate (β-TCP) started to form at 900°C, and its amount increased with increasing firing temperatures. Crystallite size increased with firing temperatures then dropped at temperatures > 1200°C. The decrease of this value was related to the β-TCP formation. Microstructural analysis revealed that the 900°C sample had a good uniform porous structure with an average pore size of 0.39 μm. The 900°C samples were coated with antimicrobial agents, including Ag-based agents (Ag nanoparticles and AgNO3) and natural plant oils (lemongrass and turmeric oils), to improve their antimicrobial activity. The samples coated with Ag-based agents presented good antimicrobial efficiency while natural plant oil-coated samples showed moderate efficiency. The obtained results suggested the possibility of developing porous samples for antimicrobial applications, using natural sources at a low cost.
Additional file 4: of Trophoblast differentiation, invasion and hormone secretion in a three-dimensional in vitro implantation model with rhesus monkey embryos
Creators: name: T. Arthur Chang
name: Bondarenko, Gennadiy
name: Gerami-Naini, Behzad
name: Drenzek, Jessica
name: Durning, Maureen
name: Garthwaite, Mark
name: Schmidt, Jenna
name: Golos, Thaddeus
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Cell Biology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Secretion of CG correlated with embryo size. The peak secretion of CG into culture medium in embryos presented in Fig. 3 is plotted against the maximal growth of embryos through days 18–21 of culture. The line presented was derived by best-fit linear regression analysis. Estimation of the correlation coefficient (Spearman’s nonparametric test) indicted that the correlation was not statistically significant (P = 0.093). (PDF 206 kb)
Rotating black hole in Rastall theory
Creators: name: Kumar, Rahul
name: Ghosh, Sushant G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Rotating black hole solutions in theories of modified gravity are important as they offer an arena to test these theories through astrophysical observation. The non-rotating black hole can be hardly tested since the black hole spin is very important in any astrophysical process. We present rotating counterpart of a recently obtained spherically symmetric exact black hole solution surrounded by perfect fluid in the context of Rastall theory, viz, rotating Rastall black hole that generalize the Kerr-Newman black hole solution. In turn, we analyze the specific cases of the Kerr-Newman black holes surrounded by matter like dust and quintessence fields. Interestingly, for a set of parameters and a chosen surrounding field, there exists a critical rotation parameter ($a=a_{E}$), which corresponds to an extremal black hole with degenerate horizons, while for $aa_{E}$ with value $a_E$ is also influenced by these parameters. We also discuss the thermodynamical quantities associated with rotating Rastall black hole, and analyze the particle motion with the behavior of effective potential.
description: 26 pages, 8 figures. Matched with the published version
Automated Classification of Phonetic Segments in Child Speech Using Raw Ultrasound Imaging
Creators: name: Ani, Saja Al
name: Cleland, Joanne
name: Zoha, Ahmed
Publisher: name: arXiv
Year: 2024
Subjects: subject: Sound (cs.SD)
subject: Artificial Intelligence (cs.AI)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Speech sound disorder (SSD) is defined as a persistent impairment in speech sound production leading to reduced speech intelligibility and hindered verbal communication. Early recognition and intervention of children with SSD and timely referral to speech and language therapists (SLTs) for treatment are crucial. Automated detection of speech impairment is regarded as an efficient method for examining and screening large populations. This study focuses on advancing the automatic diagnosis of SSD in early childhood by proposing a technical solution that integrates ultrasound tongue imaging (UTI) with deep-learning models. The introduced FusionNet model combines UTI data with the extracted texture features to classify UTI. The overarching aim is to elevate the accuracy and efficiency of UTI analysis, particularly for classifying speech sounds associated with SSD. This study compared the FusionNet approach with standard deep-learning methodologies, highlighting the excellent improvement results of the FusionNet model in UTI classification and the potential of multi-learning in improving UTI classification in speech therapy clinics.
Wellington Cenotaph
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: While in the North Island of New Zealand (Te Ika-a-Māui, Aotearoa) I visited the Wellington Cenotaph, also known as the Wellington Citizens' War Memorial. It is on the junction between Lambton Quay and Bowen Street in Wellington (Te Whanganui-a-Tara) near the Parliamentary precinct. Unfortunately, I did not have time to visit the New Zealand National War Memorial.
Additional file 1: of Comparing dedicated and designated models of integrating mental health into chronic disease care: study protocol for a cluster randomized controlled trial
Creators: name: Myers, Bronwyn
name: Crick Lund
name: Lombard, Carl
name: Joska, John
name: Levitt, Naomi
name: Butler, Christopher
name: Cleary, Susan
name: Naledi, Tracey
name: Milligan, Peter
name: Stein, Dan
name: Sorsdahl, Katherine
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 120 kb)
Measuring Polarization In Cosmic Microwave Background
Creators: name: Seljak, Uros
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Polarization induced by cosmological scalar perturbations leads to a typical anisotropy pattern, which can best be analyzed in Fourier domain. This allows one to unambiguously distinguish cosmological signal of polarization from other foregrounds and systematics, as well as from polarization induced by non-scalar perturbations. The precision with which polarization and cross-correlation power spectra can be determined is limited by cosmic variance, noise and foreground residuals. Choice of estimator can significantly improve our capability of extracting cosmological signal and in the noise dominated limit the optimal power spectrum estimator reduces the variance by a factor of two compared to the simplest estimator. If foreground residuals are important then a different estimator can be used, which eliminates systematic effects from foregrounds so that no further foreground subtraction is needed. A particular combination of Stokes $Q$ and $U$ parameters vanishes for scalar induced polarization, thereby allowing an unambiguous determination of tensor modes. Theoretical predictions of polarization in standard models show that one typically expects a signal at the level of 5-10$μ$K on small angular scales and around 1$μ$K on large scales ($l<200$). Satellite missions should be able to reach sensitivities needed for an unambiguous detection of polarization, which would help to break the degeneracies in the determination of some of the cosmological parameters.
description: 23 pages, 2 figures, AAS latex; matches the accepted version
Joan & Donald Macey - a wartime romance
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: My parents met in 1938 at an Army camp in Longworth near Oxford - my mother was volunteering in the camp shop and my father came in to buy some writing paper.These photographs show just how young they were and in 1939 my father was sent to France with the British Expeditionary Force ( BEF ) being subsequently evacuated from Dunkirk. Being almost 6' 4 " he was given a Boys anti tank rifle ("elephant gun") and dutifully waded out to the waiting ship above his head to keep it dry. Only to told "Can't bring that on 'ere mate, chuck it in the water".In 1941 he went on Op CLaymore to the Lofoten islands with No. 4 Commando and was then sent to Aldershot on OCTU - officer training.My parents were married in the URC church in Hungerford, Berks, across the road from the family home. A lady Minister officiated. 17 days later he sailed for India and was to spend the next 3.5 years there and in Burma, fighting the Japanese.His small war diaries are brief, but illuminating.My mother was a trainee infant teacher in London and watched the Battle of Britain being fought overhead. Her class were then evacuated to Taunton to avoid the blitz.In the post war period my parents went to Hannover, BAOR where my father was posted as an Executive Demolition Officer (EDO). His job was to blow up the huge reinforced concrete structures which the Nazis had built for military purposes. As he said in his typical understated style - "we made a lot of big bangs".Both my sister were born in BMH Hannover - the British Military Hospital, a fact which now confuses UK institutions such as the Passport Office and the DVLA, who have sadly forgotten their history...
Study on the Inhibition Performance of a Lipoic Acid Microcapsule Gel Composite Inhibitor in the Spontaneous Combustion of Coal
Creators: name: Liu, Jia
name: Hu, Zhidan
name: Huang, Zhian
name: Li, Wei
name: Zeng, Mengyang
name: Ling, Ziwei
name: Li, Jinyang
name: Yu, Rongxia
name: Ding, Hao
name: Zhang, Yinghua
name: Wang, Pengfei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: In order to improve the inhibition performance of an inhibitor, a microcapsule material was prepared with modified chitosan and lipoic acid as the main raw materials, and a gel material was prepared with polyethylene glycol and sodium alginate. By combining the microcapsule and gel, a composite inhibitor SAA/PEG-MALA was finally obtained, with a good inhibition effect and a long-lasting inhibition time. A scanning electron microscopy experiment showed that SAA/PEG-MALA has a unique radioactive pore structure, thus improving the moisture absorption and water retention performance. A thermogravimetric experiment showed that, after treatment with SAA/PEG-MALA, the characteristic temperature of the coal samples were increased, of which the dry cracking temperature T2 was increased by 16.9°C, and the thermal decomposition temperature T5 was increased by 72.2°C. A differential scanning calorimetry experiment showed that the transition temperature of an SAA/PEG-MALA-inhibited coal sample increased by 31.6°C, and the heat release decreased by 5828.0 J/g. A thermogravimetric infrared experiment showed that the average inhibition rate of the SAA/PEG-MALA was 94.04%, and its average inhibition life was 27.43 min. These results indicate that SAA/PEG-MALA can effectively inhibit the spontaneous combustion of coal.
Cassia alata Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Cassia
Cassia alata

description: Cassia alata, spec. nov.
 15. Cassia foliolis octojugatis ovali-oblongis: interioribus minoribus, petiolis eglandulosis, stipulis patulis. Hort. cliff. 158. Hort. ups. 100. Roy. lugdb. 467.
 Cassia sylvestris foetida, siliquis alatis. Plum. spec. 18.
 Faba dulcis. Mer. surin. 58. t. 58.
 Habitat in America calidiore. ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 378, DOI: 10.5281/zenodo.3931989
Finite quantum gravity in dS and AdS spacetimes
Creators: name: Koshelev, Alexey S.
name: Kumar, K. Sravan
name: Modesto, Leonardo
name: Rachwal, Leslaw
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We hereby study the properties of a large class of weakly nonlocal gravitational theories around the (anti-) de Sitter spacetime background. In particular, we explicitly prove that the kinetic operator for the graviton field has the same structure as the one in Einstein-Hilbert theory around any maximally symmetric spacetime. Therefore, the perturbative spectrum is the same of standard general relativity, while the propagator on any maximally symmetric spacetime is a mere generalization of the one from Einstein's gravity derived and extensively studied in several previous papers. At quantum level the range of theories here presented is superrenormalizable or finite when proper (non affecting the propagator) terms cubic or higher in curvatures are added. Finally, it is proven that for a large class of nonlocal theories, which in their actions do involve neither the Weyl nor the Riemann tensor, the theory is classically equivalent to the Einstein-Hilbert one with cosmological constant by means of a metric field redefinition at any perturbative order.
description: 24 pages, final version with journal corrections
Collisional excitation of propyne (CH$_3$CCH) by He atoms
Creators: name: Khalifa, M. Ben
name: Darna, B.
name: Loreau, J.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: A detailed interpretation of the detected emission lines of environments in which propyne (or methyl acetylene, CH$_3$CCH) is observed requires a knowledge of its collisional rate coefficients with the most abundant species in the interstellar medium, He or H$_2$. We present the first three-dimensional potential energy surface (3D-PES) for the CH$_3$CCH-He molecular complex, study the dynamics of the collision, and report the first set of rate coefficients for temperatures up to 100 K for the collisional excitation of the lowest 60 ortho rotational levels and 60 para rotational levels of CH$_3$CCH by He atoms. We computed the 3D-PES with the explicitly correlated coupled-cluster with single-, double-, and perturbative triple-excitation method, in conjunction with the augmented correlation-consistent triple zeta basis set (CCSD(T)-F12a/aug-cc-pVTZ). The 3D-PES was fitted to an analytical function. Scattering computations of pure rotational (de-)excitation of CH$_3$CCH by collision with He atoms were performed and the state-to-state cross sections were computed using the close coupling method for total energies up to 100 cm$^{-1}$ and with the coupled states approximation at higher energy for both ortho and para symmetries of CH$_3$CCH. The PES obtained is caracterized by a large anisotropy and a potential well depth of 51.04 cm$^{-1}$. By thermally averaging the collisional cross sections, we determined quenching rate coefficients for kinetic temperatures up to 100 K. A strong even $Δj$ propensity rule at almost all collision energies exists for CH$_3$CCH-He complex. To evaluate the impact of rate coefficients in the analysis of observations, we carried out non-LTE radiative transfer computations of the excitation temperatures and we demonstrate that LTE conditions are typically not fulfilled for the propyne molecule.
description: Accepted in A&A
Additional file 1: of Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
Creators: name: Galanos, Panagiotis
name: Pappas, George
name: Polyzos, Alexander
name: Kotsinas, Athanassios
name: Svolaki, Ioanna
name: Nickolaos Giakoumakis
name: Glytsou, Christina
name: Pateras, Ioannis
name: Umakanta Swain
name: Vassilis Souliotis
name: Georgakilas, Alexandros
name: Geacintov, Nicholas
name: Scorrano, Luca
name: Lukas, Claudia
name: Jiri Lukas
name: Livneh, Zvi
name: Lygerou, Zoi
name: Dipanjan Chowdhury
name: SĂ¸Rensen, Claus
name: Jiri Bartek
name: Vassilis Gorgoulis
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Figures S1. to S8 [79â 81]. (DOCX 1894 kb)
Effect of respiration and obstructive spinal pathology on cerebrospinal fluid flow
Creators: name: Ogolo, Donald Ekomobong
Publisher: name: Macquarie University
Year: 2024
Subjects: classificationCode: 320903
subject: Central nervous system

description: Background: Disorders of cerebrospinal fluid (CSF) flow within the spinal cord such as syringomyelia have been associated with debilitating and occasionally lifelong neurologic incapacitation. Respiration, specifically inspiration (which causes a drop in intrathoracic pressure) has been established to be a major physiological driver of CSF flow within the spine. However, little is known about the effect of respiration on fluid flow within the spine in the presence of CSF obstruction. The aims of this study were: (i.) to evaluate the dynamics of CSF flow within the spinal subarachnoid space with spontaneous breathing (negative intrathoracic pressure) and mechanical ventilation (positive intrathoracic pressure) in the presence and absence of CSF obstruction; and (ii.) to assess the patterns of CSF flow into the spinal cord parenchyma with positive and negative intrathoracic pressures in the presence and absence of CSF obstruction.
Methods: This study was performed on 24 Sprague-Dawley rats, 12 with laminectomy only (controls) and 12 with laminectomy and CSF obstruction at C7/T1 level. Half of each of the above groups were then either mechanically ventilated or allowed to breathe spontaneously. Indocyanine green and ovalbumin AFO-647 fluorescent tracers were then injected into the cisterna magna and real time intraoperative imaging of the tracer flow within the spinal subarachnoid space was performed. Further microscopic quantification of axial distribution of the tracer within the cord parenchyma was also conducted. 
Results: The presence of CSF obstruction reduced craniocaudal flow of CSF tracers within the spinal subarachnoid space compared to the normal cord (p < 0.0001). Additionally, in the presence of CSF obstruction, application of mechanical ventilation reduced craniocaudal CSF tracer flow compared to spontaneous breathing at the earliest time point (p = 0.0099 at 2 minutes). Conversely, in the absence of cord constriction, mechanical ventilation enhanced craniocaudal flow of CSF tracers within the subarachnoid space at the earliest time point (p = 0.0373 at 30 seconds). In the presence of CSF obstruction, spontaneous breathing was associated with greater accumulation of tracer within the entire length of the cord from C2 to T4, when compared to mechanical ventilation (p = 0.0015). 
Conclusions: Obstruction to CSF flow within the spinal subarachnoid space might be crucial in the initiation and progression of fluid disorders of the cord such as syringomyelia. Furthermore, in the presence of CSF obstruction, positive pressure ventilation might be beneficial in preventing or reducing fluid accumulation within the cord.
Pamela Hobbs née Kanis - Warrant Officer II at Bletchley Park
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: My grandmother served at Bletchley Park. As a family, we are so proud of her. I have uploaded her interviews, photos and other information to share with the world.
Analysis of non-processive molecular motor transport using renewal reward theory
Creators: name: Miles, Christopher E.
name: Lawley, Sean D.
name: Keener, James P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Subcellular Processes (q-bio.SC)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences
subject: 92C05, 60K20, 60J28, 34F05, 60H10

description: We propose and analyze a mathematical model of cargo transport by non-processive molecular motors. In our model, the motors change states by random discrete events (corresponding to stepping and binding/unbinding), while the cargo position follows a stochastic differential equation (SDE) that depends on the discrete states of the motors. The resulting system for the cargo position is consequently an SDE that randomly switches according to a Markov jump process governing motor dynamics. To study this system we (1) cast the cargo position in a renewal theory framework and generalize the renewal reward theorem and (2) decompose the continuous and discrete sources of stochasticity and exploit a resulting pair of disparate timescales. With these mathematical tools, we obtain explicit formulas for experimentally measurable quantities, such as cargo velocity and run length. Analyzing these formulas then yields some predictions regarding so-called non-processive clustering, the phenomenon that a single motor cannot transport cargo, but that two or more motors can. We find that having motor stepping, binding, and unbinding rates depend on the number of bound motors, due to geometric effects, is necessary and sufficient to explain recent experimental data on non-processive motors.
description: updated to final journal version
Corporal Franciszek Wesolowski's Service
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Corporal Franciszek Wesolowski was born and raised in Grudziadz, Poland, a garrison town. He had a very normal upbringing in the city - his father was an Officer in the Polish Cavalry for much of his life, but had retired before the Second World War.When Germany invaded Poland in 1939, he was forced to work labor for the Germans, and was abused badly. He was punished with forms of torture such as standing in a cold barrel in the basement of the house he was forced to live in, for hours on end, no matter how cold it was. This affected him for years on end, and he only spoke about it once or twice in his life.When he was of age, in 1942, he was forced into the German Wehrmacht, and served in a Grenadier Battalion. After around a year of service, in 1943, he was taken a prisoner of war in Italy, where he voluntarily enlisted in the Polish Army under British Command, under the pseudonym "Franciszek Straszkiewicz", to protect his family back home.From the 29th of March 1944, he was posted to the 1 Independent Grenadier Company (Samodzielna Kompania Grenadierów), 1st Independent Parachute Brigade, 1 Polish Corps, where he was trained to kill with only a knife. One story he told the family was that, sometime during his service, he had to kayak from a submarine in order to sneak onto land.
Non-equilibrium effects on line-of-sight size estimates of QSO absorption systems
Creators: name: Haehnelt, Martin G.
name: Rauch, Michael
name: Steinmetz, Matthias
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Estimates of the linear extent of heavy-element absorption systems along the line-of-sight to a QSO often assume that the cloud is photoionized and that the temperature takes the equilibrium value where photo-heating balances line cooling. We show that rather small deviations from this photoionization equilibrium temperature caused by additional heating processes will lead to an overestimate of the neutral hydrogen fraction and thus to an underestimate of the thickness of the absorber by about two orders of magnitude. Such temperature deviations are indicated both by observations and numerical simulations. This interpretation reconciles the discrepancy between the rather small extent of heavy-element-absorption systems parallel to the line-of-sight obtained from a standard photoionization analysis and the much larger transverse sizes estimates inferred from the observation of common absorption in the spectra of close quasar pairs.
description: 11 pages, LaTeX , 5 postscript figures included; accepted by MNRAS
Additional file 1: of Development and validation of a mental health screening tool for asylum-seekers and refugees: the STAR-MH
Creators: name: Hocking, Debbie
name: Mancuso, Serafino
name: Sundram, Suresh
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Table S1. Demographic and clinical variables of participants (Nâ =â 192). Demographic and clinical variables of participants for the total sample, including cases with missing variables. (PDF 152 kb)
The first time I got drunk
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: This record contains some recollections of Roger Coasby.
title: ADCO, Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Cart. 176 (11 H 8), f. 0002
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 176 (11 H 8), f. 0002, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 176 (11 H 8), f. 0002, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Additional file 3: of A randomised, double-blind, placebo-controlled phase 1 study of the safety, tolerability and pharmacodynamics of volixibat in overweight and obese but otherwise healthy adults: implications for treatment of non-alcoholic steatohepatitis
Creators: name: Palmer, Melissa
name: Jennings, Lee
name: Silberg, Debra
name: Bliss, Caleb
name: Martin, Patrick
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Figure S1. Frequency of stool hardness during treatment (Bristol Stool Chart scores). (PDF 1081 kb)
Cassia marilandica Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Cassia
Cassia marilandica

description: Cassia marilandica, spec. nov.
 16. Cassia foliolis octojugatis ovato-oblongis aequalibus, glandula baseos petiolorum. Hort. cliff. 159. Hort. ups. 100. Roy. lugdb. 467.
 Cassia mimosae foliis, siliqua hirsuta. Dill. elth. 351. t. 260. f. 339.
 Cassia marilandica, pinnis foliorum oblongis, calyce floris reflexo. Mart. cent. 23. t.23.
 Habitat in Virginia , Marilandia . ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 378, DOI: 10.5281/zenodo.3931989
Design and Targeting of Silver-Copper Nanoparticles for the Anti-Cancer Activity in Cancer Cells
Creators: name: Al-Tamimi, Sara
Publisher: name: Manara - Qatar Research Repository
Year: 2025
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: Backgroundsilver, copper (Ag, Cu NPs) are metallic nanoparticles that have fascinated significant interest due to the multiplicity of their application in biological sciences. It was reported that silver or copper nanoparticles have anticancer activity in inhibition the proliferation of MCF-7. Therefore, the aim of the study, to use silver-copper alloy nanoparticles (Ag-Cu NPs) in order to have strong anti-cancer activity against human breast cancer cell line MCF-7 followed with minimum side effects on normal breast cells MCF-10-A.MethodsAg-Cu NPs are synthesized by using strong reducing reagents and characterized by using a high-resolution transmission electron microscope (HR-TEM). The cytotoxic effect of the dose-dependent Ag-Cu NPs against MCF-7 and MCF-10-A was envaulted in-vitro by MTT and AlamarBlue assays. The mechanism of inducing toxicity is not known hence apoptosis by flow cytometry and fluorescence inverted microscopy was evaluated. NPs are known to produce oxidative stress and activate proteases enzyme, Hence, reactive oxygen species (ROS) in mitochondrion were studied, followed with the activity of metalloprotease enzymes MMP2 and MPP9 were also studied by western blot.ResultsThe results demonstrated that Ag-Cu NPs have high anticancer activity against MCF-7 and minimum side effects on MCF 10-A. The treatment of MCF-7 with Ag-Cu NPs, have inhibited cell viability in a dose-dependent manner followed with various concentration 5,10,15 and 20 g/mL. Furthermore, It has been noticed that the induction of necrosis on both cell lines treated with Ag-Cu NPs. ROS results showed that in MCF-7 cells treated with Ag-Cu NPs (70:30%) caused cell membrane disruption that leads to cell death. Western blot results demonstrated that due to the necrosis that leads to cell death in MCF-7 treated with Ag-Cu NPs (70:30%), an overexpression of MMP2 was also observed.ConclusionsSynthesized Ag-Cu alloy NPs successfully inhibit the proliferation and cause anti-cancer activity against MCF-7 breast cancer cells comparing to MCF 10-A normal breast cells.
Generalised Wasserstein Dice Score for Imbalanced Multi-class Segmentation using Holistic Convolutional Networks
Creators: name: Fidon, Lucas
name: Li, Wenqi
name: Garcia-Peraza-Herrera, Luis C.
name: Ekanayake, Jinendra
name: Kitchen, Neil
name: Ourselin, Sebastien
name: Vercauteren, Tom
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The Dice score is widely used for binary segmentation due to its robustness to class imbalance. Soft generalisations of the Dice score allow it to be used as a loss function for training convolutional neural networks (CNN). Although CNNs trained using mean-class Dice score achieve state-of-the-art results on multi-class segmentation, this loss function does neither take advantage of inter-class relationships nor multi-scale information. We argue that an improved loss function should balance misclassifications to favour predictions that are semantically meaningful. This paper investigates these issues in the context of multi-class brain tumour segmentation. Our contribution is threefold. 1) We propose a semantically-informed generalisation of the Dice score for multi-class segmentation based on the Wasserstein distance on the probabilistic label space. 2) We propose a holistic CNN that embeds spatial information at multiple scales with deep supervision. 3) We show that the joint use of holistic CNNs and generalised Wasserstein Dice scores achieves segmentations that are more semantically meaningful for brain tumour segmentation.
description: Accepted as an oral presentation at the MICCAI 2017 Brain Lesion (BrainLes) Workshop
An explanation for dark matter and dark energy consistent with the Standard Model of particle physics and General Relativity
Creators: name: Deur, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Analyses of internal galaxy and cluster dynamics typically employ Newton's law of gravity, which neglects the field self-interaction effects of General Relativity. This may be why dark matter seems necessary. The Universe evolution, on the other hand, is treated with the full theory, General Relativity. However, the approximations of isotropy and homogeneity, normally used to derive and solve the Universe evolution equations, effectively suppress General Relativity's field self-interaction effects and this may introduce the need for dark energy. Calculations have shown that field self-interaction increases the binding of matter inside massive systems, which may account for galaxy and cluster dynamics without invoking dark matter. In turn, energy conservation dictates that the increased binding must be balanced by an effectively decreased gravitational interaction outside the massive system. In this article, such suppression is estimated and its consequence for the Universe's evolution is discussed. Observations are reproduced without need for dark energy.
description: 12 pages, 4 figures. Version published in Eur. Phys. J. C
Additional file 3: of Measurement of alienation among adolescents: construct validity of three scales on powerlessness, meaninglessness and social isolation
Creators: name: Rayce, Signe
name: Kreiner, Svend
name: Damsgaard, Mogens
name: Nielsen, Tine
name: BjĂ¸Rn Holstein
Publisher: name: figshare
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Figure S3. Test information function: Social isolation stratified by sex and age group. (DOCX 51Â kb)
The density of prime divisors in the arithmetic dynamics of quadratic polynomials
Creators: name: Jones, Rafe
Publisher: name: arXiv
Year: 2006
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11R32 (primary) 11B37, 11C08, 60G42 (secondary)

description: We consider integer recurrences of the form a_n = f(a_{n-1}), where f is a quadratic polynomial with integer coefficients. We show, for four infinite families of f, that the set of primes dividing at least one term of such a sequence must have density zero, regardless of choice of a_0. The proof relies on tools from group theory and probability theory to develop a zero-density criterion in terms of arithmetic properties of the forward orbit of the critical point of f. This provides an analogy to results in real and complex dynamics, where analytic properties of the forward orbit of the critical point determine many global dynamical properties of f. The article also includes apparently new work on the irreducibility of iterates of quadratic polynomials.
description: 21 pages, LaTex
title: Investigating the role of yeast Glutathione peroxidase 3 and related proteins in mitochondria and peroxisomes
Creators: name: Mordas, Amelia Victoria
Publisher: name: University of Glasgow
Year: 2019

description: In Saccharomyces cerevisiae, Gpx3 is a H2O2 sensor that resides in the cytosol, the mitochondrial intermembrane space (IMS) and the peroxisomal matrix. Upstream translation from a non-AUG codon after exposure to H2O2 results in production of an N- terminally extended form, N18Gpx3, that targets the protein to mitochondria in a more efficient manner. Whilst the major role of Gpx3 in the cytosol is known, notably its interaction with (and activation of) the transcription factor Yap1, the role/s of Gpx3 and N18Gpx3 in the mitochondrial IMS and peroxisomal matrix are yet to be fully determined. Previous work published by our lab and collaborators identified the oxidoreductase Mia40 as an interactor of Gpx3; however, others were anticipated. Here, we identified two new putative IMS interactors of Gpx3: Cytochrome c (Cytc) and Cytochrome b2 (Cytb2). Cytc is an abundant electron carrier in the IMS that plays a role in both respiration and the mitochondrial IMS assembly (MIA) oxidative folding pathway, and in mammals Cytc is also involved in triggering apoptosis. In contrast, little is known about Cytb2. We focused our attention on the potential Gpx3-Cytc interaction and found that by mutating Cys64 of Gpx3, a highly conserved cysteine residue with no known function, its interaction with Cytc was affected. As both Mia40 and Cytc are components of the MIA pathway, we hypothesise that Gpx3 plays a role in oxidative folding and may be a regulator of this pathway under oxidative stress. Next, we uncovered six small proteins with no previous mitochondrial associations and went on to investigate one in particular, Ypl107w, an uncharacterised protein containing a highly conserved oxidoreductase-like domain (OXLD) that, despite being present in thousands of proteins across hundreds of species, has an unknown function. We confirmed its targeting and localisation to the mitochondrial matrix and hypothesise, based on bioinformatics and BN-PAGE data, that Ypl107w has many interactors and may be involved in mitochondrial assembly. There may also be a link between Ypl107w, Gpx3 and Cytc as ypl107wD mitochondria have lower amounts of both Gpx3 and Cytc. Finally, we confirmed the presence of Gpx3 in peroxisomes and discovered a shorter version of Mia40 along with Trx1 and Trx2 also residing in peroxisomes. We hypothesise that the targeting of these proteins occurs by previously unrecognised peroxisomal targeting signals, and that the MIA pathway may operate in both mitochondria and peroxisomes. Altogether, the work presented in this thesis adds to our knowledge of yeast Gpx3 in regards to its compartment-specific roles.