cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Star formation and Asymmetry in the spiral arms of M51-- Variable star formation caused by more than one spiral density wave
Creators: name: Henry, Alaina L.
name: Quillen, A. C.
name: Gutermuth, Robert
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In the inner 3kpc of M51 we find that logarithmic spirals provide good fits to the peak intensities in molecular gas observed by BIMA in the CO (J=1-0) emission line along the spiral arms. However, we measure significant asymmetries between the location and density of the arms observed on one side of the galaxy compared to those on the opposite side. Between a radius of 1 and 2.2 kpc the gas distribution traced in CO is lopsided with densities twice as large in one arm compared to the opposite one. In the same region, the spiral arms are offset by 20 degrees from the position of the arm on the opposite side of the galaxy after a rotation of 180 degrees. We use the ratio of CO emission to that in the Pa alpha hydrogen recombination line to estimate the efficiency of star formation along each arm. Except for a narrow region at about 2kpc where star formation is surprisingly inefficient, the gas depletion time is approximately 200 million years despite large variations in the molecular gas density in the arms. We account for the deviations from two armed bi-symmetric structure with a simple model that includes an additional three-armed spiral density wave. This model accounts for the angular offset between the arm on one side compared to its opposite, the lopsided distribution in molecular gas, and inter-arm star formation to the north east of the galaxy nucleus. Since the star formation efficiency is unaffected by the variations in gas density, and the variations in gas density can be accounted for by the presence of an additional three-armed density wave, we suggest that the star formation rate is variable, and is highest where and when the maxima of the two spiral density waves coincide or constructively add.
description: 18 pages, 7 figures, 1 table
Cheumatopsyche diehli Malicky 1997
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche diehli

description: Cheumatopsyche diehli Malicky, 1997
Fig. 207
 Cheumatopsyche diehli Malicky, 1997: 1033.
 Type locality: Indonesia (Sumatra).
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 150
Additional file 5 of Approaches to multidrug-resistant organism prevention and control in long-term care facilities for older people: a systematic review and meta-analysis
Creators: name: Wong, Valerie Wing Yu
name: Huang, Ying
name: Wei, Wan In
name: Wong, Samuel Yeung Shan
name: Kwok, Kin On
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Biotechnology
Cancer
Science Policy

description: Additional file 5. Forest plot for studies evaluating MRSA colonization.
Generation and characterization of a mitotane-resistant adrenocortical cell line
Creators: name: Seidel, Eric
name: Walenda, Gudrun
name: Messerschmidt, Clemens
name: Obermayer, Benedikt
name: Peitzsch, Mirko
name: Wallace, Paal
name: Bahethi, Rohini
name: Yoo, Taekyeong
name: Choi, Murim
name: Schrade, Petra
name: Bachmann, Sebastian
name: Liebisch, Gerhard
name: Eisenhofer, Graeme
name: Beule, Dieter
name: Scholl, Ute I.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: chemotherapy
subject: adrenolytic
subject: somatic mutations
subject: cholesterol
subject: lipids
subject: SOAT
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy. To investigate the underlying mechanisms in vitro, we here generated mitotane-resistant cell lines. After long-term pulsed treatment of HAC-15 human adrenocortical carcinoma cells with 70 µM mitotane, we isolated monoclonal cell populations of treated cells and controls and assessed their respective mitotane sensitivities by MTT assay. We performed exome sequencing and electron microscopy, conducted gene expression microarray analysis and determined intracellular lipid concentrations in the presence and absence of mitotane. Clonal cell lines established after pulsed treatment were resistant to mitotane (IC50 of 102.2 ± 7.3 µM (n = 12) vs 39.4 ± 6.2 µM (n = 6) in controls (biological replicates, mean ± s.d., P = 0.0001)). Unlike nonresistant clones, resistant clones maintained normal mitochondrial and nucleolar morphology during mitotane treatment. Resistant clones largely shared structural and single nucleotide variants, suggesting a common cell of origin. Resistance depended, in part, on extracellular lipoproteins and was associated with alterations in intracellular lipid homeostasis, including levels of free cholesterol, as well as decreased steroid production. By gene expression analysis, resistant cells showed profound alterations in pathways including steroid metabolism and transport, apoptosis, cell growth and Wnt signaling. These studies establish an in vitro model of mitotane resistance in ACC and point to underlying molecular mechanisms. They may enable future studies to overcome resistance in vitro and improve ACC treatment in vivo.
A novel evolutionary formulation of the maximum independent set problem
Creators: name: Barbosa, V. C.
name: Campos, L. C. D.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences
subject: F.2.2; I.2.8

description: We introduce a novel evolutionary formulation of the problem of finding a maximum independent set of a graph. The new formulation is based on the relationship that exists between a graph's independence number and its acyclic orientations. It views such orientations as individuals and evolves them with the aid of evolutionary operators that are very heavily based on the structure of the graph and its acyclic orientations. The resulting heuristic has been tested on some of the Second DIMACS Implementation Challenge benchmark graphs, and has been found to be competitive when compared to several of the other heuristics that have also been tested on those graphs.
From n+1-level atom chains to n-dimensional noises
Creators: name: Attal, Stephane
name: Pautrat, Yan
Publisher: name: arXiv
Year: 2004
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: In quantum physics, the state space of a countable chain of (n+1)-level atoms becomes, in the continuous field limit, a Fock space with multiplicity n. In a more functional analytic language, the continuous tensor product space over R of copies of the space C^{n+1} is the symmetric Fock space Gamma_s(L^2(R;C^n)). In this article we focus on the probabilistic interpretations of these facts. We show that they correspond to the approximation of the n-dimensional normal martingales by means of obtuse random walks, that is, extremal random walks in R^n whose jumps take exactly n+1 different values. We show that these probabilistic approximations are carried by the convergence of the basic matrix basis a^i_j(p) of $\otimes_N \CC^{n+1}$ to the usual creation, annihilation and gauge processes on the Fock space.
description: 22 pages
A Lyapunov Function for the Combined System-Optimizer Dynamics in Inexact Model Predictive Control
Creators: name: Zanelli, Andrea
name: Dinh, Quoc Tran
name: Diehl, Moritz
Publisher: name: arXiv
Year: 2020
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: In this paper, an asymptotic stability proof for a class of methods for inexact nonlinear model predictive control is presented. General Q-linearly convergent online optimization methods are considered and an asymptotic stability result is derived for the setting where a limited number of iterations of the optimizer are carried out per sampling time. Under the assumption of Lipschitz continuity of the solution, we explicitly construct a Lyapunov function for the combined system-optimizer dynamics, which shows that asymptotic stability can be obtained if the sampling time is sufficiently short. The results constitute an extension to existing attractivity results which hold in the simplified setting where inequality constraints are either not present or inactive in the region of attraction considered. Moreover, with respect to the established results on robust asymptotic stability of suboptimal model predictive control, we develop a framework that takes into account the optimizer's dynamics and does not require decrease of the objective function across iterates. By extending these results, the gap between theory and practice of the standard real-time iteration strategy is bridged and asymptotic stability for a broader class of methods is guaranteed.
description: arXiv admin note: text overlap with arXiv:1912.03140
Влияние скорости ветра и рельефа местности на загрязнение атмосферного воздуха при утилизации взрывчатых веществ
Creators: name: В.Н. Кобрин
name: Н.В. Нечипорук
name: Skob, Yurii
name: Ugryumov, Mykhaylo
name: П.Г. Кириенко
name: Korobchynskyi, Kirill
Publisher: name: figshare
Year: 2020
Subjects: subject: 50204 Environmental Impact Assessment
subject: FOS: Earth and related environmental sciences

description: Влияние скорости ветра и рельефа местности на загрязнение атмосферного воздуха при утилизации взрывчатых веществ
Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels
Creators: name: Rancan, Fiorenza
name: Volkmann, Hildburg
name: Giulbudagian, Michael
name: Schumacher, Fabian
name: Stanko, Jessica Isolde
name: Kleuser, Burkhard
name: Blume-Peytavi, Ulrike
name: Calderón, Marcelo
name: Vogt, Annika
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: tacrolimus formulation
subject: nanogels
subject: skin penetration
subject: drug delivery
subject: human excised skin
subject: Jurkat cells
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin. In this study, we compared the skin penetration of tacrolimus formulated in tNGs with a commercial 0.1% tacrolimus ointment. The penetration of the drug was investigated in ex vivo abdominal and breast skin, while different methods for skin barrier disruption were investigated to improve skin permeability or simulate inflammatory conditions with compromised skin barrier. The amount of penetrated tacrolimus was measured in skin extracts by liquid chromatography tandem-mass spectrometry (LC-MS/MS), whereas the inflammatory markers IL-6 and IL-8 were detected by enzyme-linked immunosorbent assay (ELISA). Higher amounts of tacrolimus penetrated in breast as compared to abdominal skin or in barrier-disrupted as compared to intact skin, confirming that the stratum corneum is the main barrier for tacrolimus skin penetration. The anti-proliferative effect of the penetrated drug was measured in skin tissue/Jurkat cells co-cultures. Interestingly, tNGs exhibited similar anti-proliferative effects as the 0.1% tacrolimus ointment. We conclude that polyglycerol-based nanogels represent an interesting alternative to paraffin-based formulations for the treatment of inflammatory skin conditions.
Is ADC(3) as Accurate as CC3 for Valence and Rydberg Transition Energies?
Creators: name: Loos, Pierre-François
name: Jacquemin, Denis
Publisher: name: arXiv
Year: 2019
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The search for new \emph{ab initio} models rapidly delivering accurate excited state energies and properties is one of the most active research lines of theoretical chemistry. Along with these methodological developments, the performances of known methods are constantly reassessed thanks to the emergence of new benchmark values. In this Letter, we show that, in contrast to previous claims, the third-order algebraic diagrammatic construction, ADC(3), does not yield transition energies of the same quality as the third-order coupled cluster method, CC3. There is indeed a significant difference in terms of accuracy between the two approaches, as we clearly and unambiguously demonstrate here thanks to extensive comparisons with several hundreds high-quality vertical transition energies obtained with FCI, CCSDTQ, and CCSDT. Direct comparisons with experimental 0-0 energies of small- and medium-size organic molecules support the same conclusion, which holds for both valence and Rydberg transitions, as well as singlet and triplet states. In regards of these results, we introduce a composite approach that we named ADC(2.5) which consists in averaging the ADC(2) and ADC(3) excitation energies. Although ADC(2.5) does not match the CC3 accuracy, it significantly improves the ADC(3) results, especially for vertical energies. We hope that the present contribution will stimulate further developments and, in particular, improvements of the ADC-type methods which have the indisputable advantage of being computationally lighter than their equivalent-order CC variants.
description: 8 pages, 2 figures (supporting information available)
Charge and Density Fluctuations Lock Horns : Ionic Criticality with Power-Law Forces
Creators: name: Aqua, Jean-Noel
name: Fisher, Michael E
Publisher: name: arXiv
Year: 2004
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: How do charge and density fluctuations compete in ionic fluids near gas-liquid criticality when quantum mechanical effects play a role ? To gain some insight, long-range $Φ^{\mathcal{L}}_{\pm \pm} / r^{d+σ}$ interactions (with $σ>0$), that encompass van der Waals forces (when $σ= d = 3$), have been incorporated in exactly soluble, $d$-dimensional 1:1 ionic spherical models with charges $\pm q_0$ and hard-core repulsions. In accord with previous work, when $d>\min \{σ, 2\}$ (and $q_0$ is not too large), the Coulomb interactions do not alter the ($q_0 = 0$) critical universality class that is characterized by density correlations at criticality decaying as $1/r^{d-2+η}$ with $η= \max \{0, 2-σ\}$. But screening is now algebraic, the charge-charge correlations decaying, in general, only as $1/r^{d+σ+4}$; thus $σ= 3$ faithfully mimics known \textit{non}critical $d=3$ quantal effects. But in the \textit{absence} of full ($+, -$) ion symmetry, density and charge fluctuations mix via a transparent mechanism: then the screening \textit{at criticality} is \textit{weaker} by a factor $r^{4-2η}$. Furthermore, the otherwise valid Stillinger-Lovett sum rule fails \textit{at} criticality whenever $η=0$ (as, e.g., when $σ>2$) although it remains valid if $η>0$ (as for $σ<2$ or in real $d \leq 3$ Ising-type systems).
description: 8 pages, in press in J. Phys. A, Letters to the Editor
Studies Towards the Total Synthesis of Grandilodine C and New Methods For Reversible Formation of Nitroxyl Radicals
Creators: name: Klinska, Marta
Publisher: name: The Australian National University
Year: 2017
Subjects: Total synthesis
Natural Product
Grandilodine C
Stille Coupling
Conjugate Addition
Distonic Radical
Nitroxide Mediated Polymerization
pH Switchable Reagents
Profluorescent Nitroxide

description: This thesis contains two separate research projects within the broad topic of synthetic organic chemistry. The preparation of intermediates that could be used in total synthesis of a complex natural product and an experimental verification of a computational study are reported. The first part of this thesis deals with the synthesis of organostannane carbamate reagents and their Stille cross coupling reactions with a triflate, which delivers an advanced precursor to a biologically active natural product indole alkaloid, grandilodine C. Intramolecular conjugate addition between an α,β-unsaturated methyl ester and carbamate is studied and alternative approaches towards the target compound, such as iodolactonization and oxymercuration are investigated. The second part of this thesis describes the synthesis of nitroxides and alkoxyamines containing carboxylic acid functional groups and the concept of pH switchable nitroxide mediated polymerization is explored. Several synthetic and analytical experiments are designed in an effort to verify the computational studies of stabilizing interactions in radical anions. Investigations into a hydrogen atom transfer reaction between profluorescent nitroxide and 4-carboxy TEMPO hydroxylamine reveal significant rate acceleration in low polarity solvent, which is in good agreement with computational predictions. More generally, these findings provide the first experimental proof of the theoretical concept that electrostatic stabilization of delocalized radicals remains particularly significant in low polarity environments.
Additional file 3 of Effect of therapeutic versus prophylactic anticoagulation therapy on clinical outcomes in COVID-19 patients: a systematic review with an updated meta-analysis
Creators: name: Duo, Hong
name: Li, Yahui
name: Sun, Yujie
name: Wei, Liang
name: Wang, Ziqing
name: Fang, Fang
name: Zhong, Yuxin
name: Huang, Jiao
name: Luo, Linjie
name: Peng, Zhiyong
name: Pan, Huaqin
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Cancer
Science Policy
Virology
Computational Biology

description: Additional file 3. Search Strategies.
Interactions of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) with the Immune System: Implications for Inflammation and Cancer
Creators: name: Beyer, Katharina
name: Baukloh, Ann-Kathrin
name: Stoyanova, Ani
name: Kamphues, Carsten
name: Sattler, Arne
name: Kotsch, Katja
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: TRAIL
subject: apoptosis
subject: cancer
subject: inflammation
subject: immune system
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL has historically been distinct from the Fas ligand and TNFα in terms of selective apoptosis induction in tumor cells and has a nearly non-existent systemic toxicity. Consequently, in the search for an ideal drug for tumor therapy, TRAIL rapidly drew interest, promising effective tumor control with minimal side effects. However, euphoria gave way to disillusionment as it turned out that carcinoma cells possess or can acquire resistance to TRAIL-induced apoptosis. Additionally, studies on models of inflammation and autoimmunity revealed that TRAIL can influence immune cells in many different ways. While TRAIL was initially found to be an important player in tumor defense by natural killer cells or cytotoxic T cells, additional effects of TRAIL on regulatory T cells and effector T cells, as well as on neutrophilic granulocytes and antigen-presenting cells, became focuses of interest. The tumor-promoting effects of these interactions become particularly important for consideration in cases where tumors are resistant to TRAIL-induced apoptosis. Consequently, murine models have shown that TRAIL can impair the tumor microenvironment toward a more immunosuppressive type, thereby promoting tumor growth. This review summarizes the current state of knowledge on TRAIL’s interactions with the immune system in the context of cancer.
title: Modeling Geographic Population Dispersion Utilizing Geospatial Information System Environment Agents in an Agent Based Model
Creators: name: Liebert, Karl D.
Publisher: name: Old Dominion University Libraries
Year: 2008

description: New capabilities in agent based model (ABM) environments are opening the door to the creation of ABM that may incorporate high-quality, real world environment data in the form of Geospatial Information System (GIS) files . In the past, GJS environments were only possible through extensive software development efforts focused on specific model applications.

This thesis explores the value and issues of using GIS data to provide an ABM environment. It examines the ability of ABM development environments (DE) to support GIS environment data. The selected ABM DE is then used to model population behavior in an environment defined by authoritative GIS shapefiles. The empirical and statistical examination of the model shows the validity of this approach to modeling population-environment interaction.

The research in this thesis demonstrates the applicability of the GJS ABM paradigm to the examination of population interaction with its environment. It introduces the next steps in making GIS ABM more usable for the purpose of the study of population geography.
A Synoptic X-ray Study of M31 with the Chandra-HRC
Creators: name: Williams, Benjamin F.
name: Garcia, Michael R.
name: Kong, Albert K. H.
name: Primini, Frank A.
name: King, A. R.
name: Di Stefano, Rosanne
name: Murray, Stephen S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have obtained 17 epochs of Chandra High Resolution Camera (HRC) snapshot images, each covering most of the M31 disk. The data cover a total baseline of 2.5 years and contain a mean effective exposure of 17 ks. We have measured the mean fluxes and long-term lightcurves for 166 objects detected in these data. At least 25% of the sources show significant variability. The cumulative luminosity function (CLF) of the disk sources is well-fit by a power-law with a slope comparable to those observed in typical elliptical galaxies. The CLF of the bulge is a broken power law similar to measurements made by previous surveys. We note several sources in the southwestern disk with L_X > 10^{37} erg/s . We cross-correlate all of our sources with published optical and radio catalogs, as well as new optical data, finding counterpart candidates for 55 sources. In addition, 17 sources are likely X-ray transients. We analyze follow-up HST WFPC2 data of two X-ray transients, finding F336W (U-band equivalent) counterparts. In both cases, the counterparts are variable. In one case, the optical counterpart is transient with F336W = 22.3 +/- 0.1 mag. The X-ray and optical properties of this object are consistent with a ~10 solar mass black hole X-ray nova with an orbital period of ~20 days. In the other case, the optical counterpart varies between F336W = 20.82 +/- 0.06 mag and F336W = 21.11 +/- 0.02 mag. Ground-based and HST observations show this object is bright (V = 18.8 +/- 0.1) and slightly extended. Finally, the frequency of bright X-ray transients in the M31 bulge suggests that the ratio of neutron star to black hole primaries in low-mass X-ray binaries (NS/BH) is ~1.
description: 68 pages (27 text), 8 tables, 16 figures, 1 appendix, accepted by ApJ; accepted version contains reorganized text, new tables and figures, and updated results
RDD-Eclat: Approaches to Parallelize Eclat Algorithm on Spark RDD Framework
Creators: name: Singh, Pankaj
name: Singh, Sudhakar
name: Mishra, P. K.
name: Garg, Rakhi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Databases (cs.DB)
subject: Data Structures and Algorithms (cs.DS)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Initially, a number of frequent itemset mining (FIM) algorithms have been designed on the Hadoop MapReduce, a distributed big data processing framework. But, due to heavy disk I/O, MapReduce is found to be inefficient for such highly iterative algorithms. Therefore, Spark, a more efficient distributed data processing framework, has been developed with in-memory computation and resilient distributed dataset (RDD) features to support the iterative algorithms. On the Spark RDD framework, Apriori and FP-Growth based FIM algorithms have been designed, but Eclat-based algorithm has not been explored yet. In this paper, RDD-Eclat, a parallel Eclat algorithm on the Spark RDD framework is proposed with its five variants. The proposed algorithms are evaluated on the various benchmark datasets, which shows that RDD-Eclat outperforms the Spark-based Apriori by many times. Also, the experimental results show the scalability of the proposed algorithms on increasing the number of cores and size of the dataset.
description: 16 pages, 6 figures, ICCNCT 2019
Neonatal White Matter Maturation Is Associated With Infant Language Development
Creators: name: Sket, Georgina M.
name: Overfeld, Judith
name: Styner, Martin
name: Gilmore, John H.
name: Entringer, Sonja
name: Wadhwa, Pathik D.
name: Rasmussen, Jerod M.
name: Buss, Claudia
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: white matter development
subject: infant language development
subject: diffusion tensor imaging
subject: receptive language development
subject: neonatal neuroimaging
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: While neonates have no sophisticated language skills, the neural basis for acquiring this function is assumed to already be present at birth. Receptive language is measurable by 6 months of age and meaningful speech production by 10-18 months of age. Fiber tracts supporting language processing include the corpus callosum (CC), which plays a key role in the hemispheric lateralization of language; the left arcuate fasciculus (AF), which is associated with syntactic processing; and the right AF, which plays a role in prosody and semantics. We examined if neonatal maturation of these fiber tracts is associated with receptive language development at 12 months of age. Methods: Diffusion-weighted imaging (DWI) was performed in 86 infants at 26.6 ± 12.2 days post-birth. Receptive language was assessed via the MacArthur-Bates Communicative Development Inventory at 12 months of age. Tract-based fractional anisotropy (FA) was determined using the NA-MIC atlas-based fiber analysis toolkit. Associations between neonatal regional FA, adjusted for gestational age at birth and age at scan, and language development at 12 months of age were tested using ANOVA models. Results: After multiple comparisons correction, higher neonatal FA was positively associated with receptive language at 12 months of age within the genu (p < 0.001), rostrum (p < 0.001), and tapetum (p < 0.001) of the CC and the left fronto-parietal AF (p = 0.008). No significant clusters were found in the right AF. Conclusion: Microstructural development of the CC and the AF in the newborn is associated with receptive language at 12 months of age, demonstrating that interindividual variation in white matter microstructure is relevant for later language development, and indicating that the neural foundation for language processing is laid well ahead of the majority of language acquisition. This suggests that some origins of impaired language development may lie in the intrauterine and potentially neonatal period of life. Understanding how interindividual differences in neonatal brain maturity relate to the acquisition of function, particularly during early development when the brain is in an unparalleled window of plasticity, is key to identifying opportunities for harnessing neuroplasticity in health and disease.
Cheumatopsyche lesnei
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche lesnei

description: Cheumatopsyche lesnei (Mosely, 1932)
 Hydropsychodes lesnei Mosely, 1932: 4.
 Cheumatopsyche lesnei (Mosely, 1932); Mosely 1939: 27.
 Cheumatopsyche uncata Kimmins, 1957; Kimmins 1960: 257.
 Type locality: Mozambique.
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 152
Additional file 1 of Associations of eating speed with fat distribution and body shape vary in different age groups and obesity status
Creators: name: Ni, Saili
name: Jia, Menghan
name: Wang, Xuemiao
name: Hong, Yun
name: Zhao, Xueyin
name: Zhang, Liang
name: Ru, Yuan
name: Yang, Fei
name: Zhu, Shankuan
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Cardiology

description: Additional file 1. Sensitivity and interaction analyses.
Web of Science & InCites Data for VIVO Research Analytics Platform (VIVO RAP)
Creators: name: Falcoz, Franck
name: Steensboe, Christina
name: Lauridsen, Nikoline Dohm
name: Lowe, Brian
name: Ibanez, Karen Hytteballe
name: Sandfær, Mogens
Publisher: name: figshare
Year: 2020
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences

description: This report provides an overview of the data sources used to develop the VIVO RAP as well as the data changes and enhancements completed to serve the use case of the VIVO RAP better.
Interactions in high-mobility 2D electron and hole systems
Creators: name: Galaktionov, E. A.
name: Savchenko, A. K.
name: Safonov, S. S.
name: Proskuryakov, Y. Y.
name: Li, L.
name: Pepper, M.
name: Simmons, M. Y.
name: Ritchie, D. A.
name: Linfield, E. H.
name: Kvon, Z. D.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Electron-electron interactions mediated by impurities are studied in several high-mobility two-dimensional (electron and hole) systems where the parameter $k_BTτ/\hbar $ changes from 0.1 to 10 ($τ$ is the momentum relaxation time). This range corresponds to the \textit{intermediate} and \textit {ballistic} regimes where only a few impurities are involved in electron-electron interactions. The interaction correction to the Drude conductivity is detected in the temperature dependence of the resistance and in the magnetoresistance in parallel and perpendicular magnetic fields. The effects are analysed in terms of the recent theories of electron interactions developed for the ballistic regime. It is shown that the character of the fluctuation potential (short-range or long-range) is an important factor in the manifestation of electron-electron interactions in high-mobility 2D systems.
description: 22 pages, 11 figures; to appear in proceedings of conference "Fundamental Problems of Mesoscopic Physics", Granada, Spain, 6-11 September, 2003
A multimodal neuroimaging classifier for alcohol dependence
Creators: name: Guggenmos, Matthias
name: Schmack, Katharina
name: Veer, Ilya M.
name: Lett, Tristram
name: Sekutowicz, Maria
name: Sebold, Miriam
name: Garbusow, Maria
name: Sommer, Christian
name: Wittchen, Hans-Ulrich
name: Zimmermann, Ulrich S.
name: Smolka, Michael N.
name: Walter, Henrik
name: Heinz, Andreas
name: Sterzer, Philipp
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: magnetic resonance imaging
subject: multimodal neuroimaging
subject: MRI
subject: alcohol dependence
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: With progress in magnetic resonance imaging technology and a broader dissemination of state-of-the-art imaging facilities, the acquisition of multiple neuroimaging modalities is becoming increasingly feasible. One particular hope associated with multimodal neuroimaging is the development of reliable data-driven diagnostic classifiers for psychiatric disorders, yet previous studies have often failed to find a benefit of combining multiple modalities. As a psychiatric disorder with established neurobiological effects at several levels of description, alcohol dependence is particularly well-suited for multimodal classification. To this aim, we developed a multimodal classification scheme and applied it to a rich neuroimaging battery (structural, functional task-based and functional resting-state data) collected in a matched sample of alcohol-dependent patients (N = 119) and controls (N = 97). We found that our classification scheme yielded 79.3% diagnostic accuracy, which outperformed the strongest individual modality - grey-matter density - by 2.7%. We found that this moderate benefit of multimodal classification depended on a number of critical design choices: a procedure to select optimal modality-specific classifiers, a fine-grained ensemble prediction based on cross-modal weight matrices and continuous classifier decision values. We conclude that the combination of multiple neuroimaging modalities is able to moderately improve the accuracy of machine-learning-based diagnostic classification in alcohol dependence.
CNRS-IHTP ARC 3018 (1-9) : Inventaire des archives de La campagne pour la libération de Miguel Angel Estrella. (17 décembre 1977-17 février 1980)
Creators: name: IHTP
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019

description: Inventaire complet ARC 3018 (1-9) Archives de La campagne pour la libération de Miguel Angel Estrella. (17 décembre 1977-17 février 1980)de la bibliothèque de l'IHTP.
Cheumatopsyche rubachi Mey 1995
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche rubachi

description: Cheumatopsyche rubachi Mey, 1995
 Cheumatopsyche rubachi Mey, 1995: 201.
 Type locality: Philippines.
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 153
Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma
Creators: name: Richter, Günther H.S.
name: Hensel, Tim
name: Schmidt, Oxana
name: Saratov, Vadim
name: Heyking, Kristina Von
name: Becker-Dettling, Fiona
name: Prexler, Carolin
name: Yen, Hsi-Yu
name: Steiger, Katja
name: Fulda, Simone
name: Dirksen, Uta
name: Weichert, Wilko
name: Wang, Shudong
name: Burdach, Stefan
name: Schäfer, Beat W.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Ewing sarcoma
subject: tumor growth
subject: CDK9
subject: BRD4
subject: combination therapy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Previously, we used inhibitors blocking BET bromodomain binding proteins (BRDs) in Ewing sarcoma (EwS) and observed that long term treatment resulted in the development of resistance. Here, we analyze the possible interaction of BRD4 with cyclin-dependent kinase (CDK) 9. Methods: Co-immunoprecipitation experiments (CoIP) to characterize BRD4 interaction and functional consequences of inhibiting transcriptional elongation were assessed using drugs targeting of BRD4 or CDK9, either alone or in combination. Results: CoIP revealed an interaction of BRD4 with EWS-FLI1 and CDK9 in EwS. Treatment of EwS cells with CDKI-73, a specific CDK9 inhibitor (CDK9i), induced a rapid downregulation of EWS-FLI1 expression and block of contact-dependent growth. CDKI-73 induced apoptosis in EwS, as depicted by cleavage of Caspase 7 (CASP7), PARP and increased CASP3 activity, similar to JQ1. Microarray analysis following CDKI-73 treatment uncovered a transcriptional program that was only partially comparable to BRD inhibition. Strikingly, combined treatment of EwS with BRD- and CDK9-inhibitors re-sensitized cells, and was overall more effective than individual drugs not only in vitro but also in a preclinical mouse model in vivo. Conclusion: Treatment with BRD inhibitors in combination with CDK9i offers a new treatment option that significantly blocks the pathognomonic EWS-ETS transcriptional program and malignant phenotype of EwS.
IDENTIFICAÇÃO DAS AÇÕES EMPRESARIAIS A PARTIR DA PERCEPÇÃO DO CONSUMIDOR - Dissertação-Fernando Martins Fontes - Metodista de São Paulo.pdf
Creators: name: Fontes, Fernando
Publisher: name: figshare
Year: 2020
Subjects: subject: 80203 Computational Logic and Formal Languages
subject: FOS: Computer and information sciences

description: IDENTIFICAÇÃO DAS AÇÕES EMPRESÁRIAS, PARCEIRA DA PERCEPÇÃO DO CONSUMIDOR - Dissertação-Fernando Martins Fontes - Metodista de São Paulo
Cheumatopsyche schwendingeri Malicky & Chantaramongkol 1997
Creators: name: Oláh, János
name: Johanson, Kjell Arne
name: Barnard, Peter C.
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Hydropsychidae
Cheumatopsyche
Cheumatopsyche schwendingeri

description: Cheumatopsyche schwendingeri Malicky & Chantaramongkol, 1997
 Cheumatopsyche schwendingeri Malicky & Chantaramongkol, in Malicky 1997:1033.
 Type locality: Thailand.
description: Published as part of Oláh, János, Johanson, Kjell Arne & Barnard, Peter C., 2008, Revision of the Oriental and Afrotropical species of Cheumatopsyche Wallengren (Hydropsychidae, Trichoptera), pp. 1-171 in Zootaxa 1738 on page 153
A Hybrid Two-layer Feature Selection Method Using GeneticAlgorithm and Elastic Net
Creators: name: Amini, Fatemeh
name: Hu, Guiping
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Feature selection, as a critical pre-processing step for machine learning, aims at determining representative predictors from a high-dimensional feature space dataset to improve the prediction accuracy. However, the increase in feature space dimensionality, comparing to the number of observations, poses a severe challenge to many existing feature selection methods with respect to computational efficiency and prediction performance. This paper presents a new hybrid two-layer feature selection approach that combines a wrapper and an embedded method in constructing an appropriate subset of predictors. In the first layer of the proposed method, the Genetic Algorithm(GA) has been adopted as a wrapper to search for the optimal subset of predictors, which aims to reduce the number of predictors and the prediction error. As one of the meta-heuristic approaches, GA is selected due to its computational efficiency; however, GAs do not guarantee the optimality. To address this issue, a second layer is added to the proposed method to eliminate any remaining redundant/irrelevant predictors to improve the prediction accuracy. Elastic Net(EN) has been selected as the embedded method in the second layer because of its flexibility in adjusting the penalty terms in regularization process and time efficiency. This hybrid two-layer approach has been applied on a Maize genetic dataset from NAM population, which consists of multiple subsets of datasets with different ratio of the number of predictors to the number of observations. The numerical results confirm the superiority of the proposed model.
Carvacrol ameliorates acute campylobacteriosis in a clinical murine infection model
Creators: name: Mousavi, Soraya
name: Schmidt, Anna‑Maria
name: Escher, Ulrike
name: Kittler, Sophie
name: Kehrenberg, Corinna
name: Thunhorst, Elisa
name: Bereswill, Stefan
name: Heimesaat, Markus M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Carvacrol
subject: Anti‑pathogenic and anti‑inflammatory properties
subject: Campylobacter jejuni
subject: Secondary abiotic IL‑10−/− mice
subject: Pro‑inflammatory immune responses
subject: Bacterial translocation
subject: Host–pathogen‑interaction
subject: Intestinal immunopathology,
subject: Extra‑intestinal and systemic immune responses
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: The prevalence of human infections with the zoonotic pathogen Campylobacter jejuni is rising worldwide. Therefore, the identification of compounds with potent anti-pathogenic and anti-inflammatory properties for future therapeutic and/or preventive application to combat campylobacteriosis is of importance for global health. Results of recent studies suggested carvacrol (4-isopropyl-2-methylphenol) as potential candidate molecule for the treatment of campylobacteriosis in humans and for the prevention of Campylobacter colonization in farm animals. Results: To address this in a clinical murine infection model of acute campylobacteriosis, secondary abiotic IL-10-/- mice were subjected to synthetic carvacrol via the drinking water starting 4 days before peroral C. jejuni challenge. Whereas at day 6 post-infection placebo treated mice suffered from acute enterocolitis, mice from the carvacrol cohort not only harbored two log orders of magnitude lower pathogen loads in their intestines, but also displayed significantly reduced disease symptoms. Alleviated campylobacteriosis following carvacrol application was accompanied by less distinct intestinal apoptosis and pro-inflammatory immune responses as well as by higher numbers of proliferating colonic epithelial cells. Remarkably, the inflammation-ameliorating effects of carvacrol treatment were not restricted to the intestinal tract, but could also be observed in extra-intestinal organs such as liver, kidneys and lungs and, strikingly, systemically as indicated by lower IFN-γ, TNF, MCP-1 and IL-6 serum concentrations in carvacrol versus placebo treated mice. Furthermore, carvacrol treatment was associated with less frequent translocation of viable C. jejuni originating from the intestines to extra-intestinal compartments. Conclusion: The lowered C. jejuni loads and alleviated symptoms observed in the here applied clinical murine model for human campylobacteriosis highlight the application of carvacrol as a promising novel option for both, the treatment of campylobacteriosis and hence, for prevention of post-infectious sequelae in humans, and for the reduction of C. jejuni colonization in the intestines of vertebrate lifestock animals.
Sinella curviseta Brook 1882
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Entomobryidae
Sinella
Sinella curviseta

description: Sinella curviseta Brook, 1882 *
Sinella curviseta Brook, 1882: 544.
DISTRIBUTION. — Ariège. Grottede Moulis (Christiansen 1970b). Paris. Serres du Muséum national d’Histoire naturelle de Paris (Delamare Deboutteville 1950a; D’Haese 2002).
TAXONOMIE. — Delamare Deboutteville 1950a (redescription).
ÉCOLOGIE. — Christiansen 1970b (régime alimentaire).
DONNÉES MOLÉCULAIRES. — D’Haese 2002 (phylogénie).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 395, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272
Additional file 7 of Effect of therapeutic versus prophylactic anticoagulation therapy on clinical outcomes in COVID-19 patients: a systematic review with an updated meta-analysis
Creators: name: Duo, Hong
name: Li, Yahui
name: Sun, Yujie
name: Wei, Liang
name: Wang, Ziqing
name: Fang, Fang
name: Zhong, Yuxin
name: Huang, Jiao
name: Luo, Linjie
name: Peng, Zhiyong
name: Pan, Huaqin
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Cancer
Science Policy
Virology
Computational Biology

description: Additional file 7: Fig. S1. Mortality of therapeutic anti-coagulation vs. prophylactic anticoagulation in RCTs. Fig. S2. Major bleeding of therapeutic anti-coagulation vs. prophylactic anticoagulation in RCTs. Fig. S3. Mortality of therapeutic anti-coagulation vs. prophylactic anticoagulation in OBs. Fig. S4. Major bleeding of therapeutic anti-coagulation vs. prophylactic anticoagulation in OBs. Fig. S5. Subgroup analysis of thromboembolism among critically or non-critically ill patients in OBs. Fig. S6. Subgroup analysis of mortality in studies of patients with high d-dimer level. Fig. S7. Sensitivity analysis of mortality in OBs. Fig. S8. Funnel plot: Mortality of RCTs. Fig. S9. Funnel plot: Major bleeding of RCTs. Fig. S10. Funnel plot: Mortality of OBs. Fig. S11. Funnel plot: Major bleeding of OBs.
Can differently prepared mixed states be distinguished?
Creators: name: Tolar, Jiri
name: Hajicek, Petr
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A measurement has been proposed by B. d'Espagnat that would distinguish from one another some ensembles that are differently prepared but correspond to the same density matrix. Here, the idea is modified so that it becomes applicable to much more general situations. The method is illustrated in simple examples. Some matter of concern might then be that information could be transmitted by methods based on our idea in the EPR kind of experiments. A simple proof is given that this is impossible.
description: 5 pages. This version published in Physics Letters A contains improvements made according to detailed critical comments by Professor B. d'Espagnat
Real-time monitoring of driver drowsiness on mobile platforms using 3D neural networks
Creators: name: Wijnands, Jasper S.
name: Thompson, Jason
name: Nice, Kerry A.
name: Aschwanden, Gideon D. P. A.
name: Stevenson, Mark
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: I.4.9; I.4.8; I.2.10
subject: 68T45 (Primary) 68U10 (Secondary)

description: Driver drowsiness increases crash risk, leading to substantial road trauma each year. Drowsiness detection methods have received considerable attention, but few studies have investigated the implementation of a detection approach on a mobile phone. Phone applications reduce the need for specialised hardware and hence, enable a cost-effective roll-out of the technology across the driving population. While it has been shown that three-dimensional (3D) operations are more suitable for spatiotemporal feature learning, current methods for drowsiness detection commonly use frame-based, multi-step approaches. However, computationally expensive techniques that achieve superior results on action recognition benchmarks (e.g. 3D convolutions, optical flow extraction) create bottlenecks for real-time, safety-critical applications on mobile devices. Here, we show how depthwise separable 3D convolutions, combined with an early fusion of spatial and temporal information, can achieve a balance between high prediction accuracy and real-time inference requirements. In particular, increased accuracy is achieved when assessment requires motion information, for example, when sunglasses conceal the eyes. Further, a custom TensorFlow-based smartphone application shows the true impact of various approaches on inference times and demonstrates the effectiveness of real-time monitoring based on out-of-sample data to alert a drowsy driver. Our model is pre-trained on ImageNet and Kinetics and fine-tuned on a publicly available Driver Drowsiness Detection dataset. Fine-tuning on large naturalistic driving datasets could further improve accuracy to obtain robust in-vehicle performance. Overall, our research is a step towards practical deep learning applications, potentially preventing micro-sleeps and reducing road trauma.
description: 13 pages, 2 figures, 'Online First' version. For associated mp4 files, see journal website