cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Adeno-associated viral (AAV) vector-mediated therapeutics for diabetic cardiomyopathy – Current and future perspectives
Creators: name: Prakoso, D
name: Tate, M
name: de Blasio, MJ
name: Ritchie, Rebecca
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Diabetes increases the prevalence of heart failure by 6–8-fold, independent of other comorbidities such as hypertension and coronary artery disease, a phenomenon termed diabetic cardiomyopathy. Several key signalling pathways have been identified that drive the pathological changes associated with diabetes-induced heart failure. This has led to the development of multiple pharmacological agents that are currently available for clinical use. While fairly effective at delaying disease progression, these treatments do not reverse the cardiac damage associated with diabetes. One potential alternative avenue for targeting diabetes-induced heart failure is the use of adeno-associated viral vector (AAV) gene therapy, which has shown great versatility in a multitude of disease settings. AAV gene therapy has the potential to target specific cells or tissues, has a low host immune response and has the possibility to represent a lifelong cure, not possible with current conventional pharmacotherapies. In this review, we will assess the therapeutic potential of AAV gene therapy as a treatment for diabetic cardiomyopathy.
Negotiating the politics of emplacement: the Prestes Maia occupation in São Paulo, Brazil, and the ruka Folilche Aflaiai in Santiago de Chile
Creators: name: Caulkins, Matthew
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 330410
subject: Urban analysis and development
classificationCode: 440407
subject: Socio-economic development
classificationCode: 440714
subject: Urban policy

description: This thesis critically explores what negotiating a politics of emplacement looks like by engaging with two urban property struggles in Latin America. The thesis refines our understanding of the importance of space in resistance politics as space provides not only location but also is deployed strategically and is the base for the creation of resistance identities. The research analyses the resurgence of the local Mapuche (Indigenous) spaces in Santiago de Chile and a squatting movement in downtown São Paulo, Brazil. Both case studies are grounded in extensive fieldwork in each city. Two sets of semi-structured qualitative interviews were produced with participants at each site and with government officials in each city. The thesis analyses the politics of emplacement to investigate the spatial qualities of the resistance at these sites. This politics is a positioning to resist but also the creation of a place from which to resist. The emplacements analysed include three moments: gaining access to spaces in the city; transforming these spaces into differential social spaces; and politicising those spaces.

The discussion presented in this thesis shows how the emplacements create narratives of resistance in relation to space, property and territory. The groups at each of the two struggles create a differential space through their intense mobilisation and spatial politics. They build on top of that spatial politics to create alternative property arrangements at the sites. These alternative forms of property engage with the fetishism for legal formality of the two local Latin American states. And the groups change internal and external territorial relations to build up a fragmented territoriality in the city. In this sense this thesis contributes to these actually existing struggles against displacement but avoids reinforcing the role of state recognised and sanctioned forms of property.
Additional file 5 of Cyclophosphamide induces ovarian granulosa cell ferroptosis via a mechanism associated with HO-1 and ROS-mediated mitochondrial dysfunction
Creators: name: Chen, Hui
name: Nie, Ping
name: Li, Jingling
name: Wu, Yongqi
name: Yao, Bo
name: Yang, Yabing
name: Lash, Gendie E.
name: Li, Ping
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology

description: Additional file 5: table S4 Top 10 hub genes based on MCC score among co-expressed genes in DEGs and mitochondria.
Analysis of coffee-herbal beverages for potential benefits against dementia diseases
Creators: name: Yu, Tao
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 310104
subject: Cell neurochemistry
classificationCode: 340101
subject: Analytical spectrometry
classificationCode: 340406
subject: Molecular medicine
classificationCode: 340499
subject: Medicinal and biomolecular chemistry not elsewhere classified

description: The research strategy is focused on the potential prevention and treatment of cognitive impairment by recommending the consumption of herbal-coffee beverages as early as possible in life. General methods applicable for the analysis and extraction that are suitable for the preparation of a range of herbal-coffee beverages have been found. The herb-bioactive compounds are effectively extracted simply by using a coffee machine or microwave heating. These herbal-coffee beverages may provide significant neuro-protection against dementia and Alzheimer’s disease, including the development of the first examples containing ginger, liquorice and ginseng in coffee brews. Caffeine, caffeic acid and Vitamin B1 combined with HEWL to strongly inhibit ThT fluorescence. A small study of the perception and sensory responses to the new beverages was undertaken.
Additional file 1 of Evaluation of a proteomic signature coupled with the kidney failure risk equation in predicting end stage kidney disease in a chronic kidney disease cohort
Creators: name: Ramírez Medina, Carlos Raúl
name: Ali, Ibrahim
name: Baricevic-Jones, Ivona
name: Saleem, Moin A.
name: Whetton, Anthony D.
name: Kalra, Philip A.
name: Geifman, Nophar
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Additional file 1: Supplementary Methods S1.
The in personam jurisdiction of equity: a cross-border mechanism to control corporate malfeasance
Creators: name: CLARENCE, Belinda
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 480103
subject: Corporations and associations law
classificationCode: 480405
subject: Law and society and socio-legal research
classificationCode: 480499
subject: Law in context not elsewhere classified

description: The purpose of this dissertation is to set out a novel legal mechanism by which the actions of multinational corporations can be legally controlled, when they operate in jurisdictions that lack either the institutions of state or the political will to regulate corporate malfeasance.  The problem arises because the power of a sovereign state and hence its ability to apply its law generally extends only as far as its territorial boundaries but multinational corporations operate globally.  The general law jurisdiction of equity is suited to this task because equity is concerned with both property rights and the personal conduct of defendants.

The relevant jurisdiction of equity dates from a rule of private international law established in the seminal 1750 case of Penn v Lord Baltimore.  This was a protracted dispute over the location of the boundary between Pennsylvania and Maryland that was eventually settled in an English court.   Equity was able to act extra-territorially because equity acts on the person of the defendant.

This dissertation has argued that the in personam jurisdiction has been unduly restricted in its operation by the Mozambique Rule, as well as by excessive deference to the executive in relation to state immunity and the act of state doctrine.   Released from these fetters, this jurisdiction can operate as it once did in Penn to provide justice for litigants in complex modern disputes in the extractive industries where the technical application of the common law and the complexities of transnational litigation deny justice to plaintiffs in host states.
Dicranella howei Renauld & Cardot 1893
Creators: name: Papp, Beáta
name: Pantović, Jovana
name: Sabovljević, Marko S.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Plantae
Bryophyta
Bryopsida
Dicranales
Dicranaceae
Dicranella
Dicranella howei

description: Dicranella howei Renauld & Cardot
 SPECIMENS EXAMINED. — Republic of Northern Macedonia. After Sveta Petka church in Sveti Naum monastery complex at Ohrid lake, source area of the Crni Drim river, on soil, 40°54’43.7”N, 20°44’32.1”E, 715 m a.s.l., 17.X.2016, leg. Papp B. and Pantovi ć J. s.n., BP[BP 193579] — Dolno Konjsko village at Ohrid lake, lime containing schistose rock on the roadside, 41°03’37.6”N, 20°48’11.6”E, 705 m a.s.l., 21.X.2016, leg. Papp B. and Pantovi ć J. s.n., BP[BP 193728] — Towards Otoševo from Ohrid lake, at the roadside before Vidikovec, conglomerate rock, 40°57’57.1”N, 20°48’20.8”E, 1135 m a.s.l., 21.X.2016, leg. Papp B. and Pantovi ć J. s.n., BP[BP 193735].   REMARKS
 This species is widely distributed in Europe in areas of Mediterranean influence (Smith 2004), being also present in central Europe (Hodgetts 2015). It was reported previously from Bosnia-Herzegovina, Croatia, Greece, Montenegro and European Turkey among Balkan countries (Sabovljević et al. 2008; Ros et al. 2013; Hodgetts 2015), where it seems not to be very rare in adequate sites. According to Ros et al. (2013), in the other Mediterranean territories, it was not recorded only in Andorra, Egypt, Jordan and Syria.
description: Published as part of Papp, Beáta, Pantović, Jovana & Sabovljević, Marko S., 2019, Additions to the bryophyte flora of the Republic of Northern Macedonia, pp. 159-166 in Cryptogamie, Bryologie 20 (15) on page 162, DOI: 10.5252/cryptogamie-bryologie2019v40a15, http://zenodo.org/record/12215549
Mutation analysis of KCND3 gene in spinocerebellar ataxia 19 and its pathogenesis
Creators: name: 李梦杰(Mengjie Li)
Publisher: name: CNGB
Year: 2022
Subjects: Transcriptome or Gene expression
Monoisolate
Medical

description: We established induced pluripotent stem cells (iPSCs) derived from SCA19/22 patients (n=2) and healthy people (n=2). When the neurons cultured to 30 days, RNA was extracted with Trizol. The final cDNA libraries were subjected to FLOMIN109 flow cells and analyzed on a PromethION platform at Biomarker Technology Company.
Writing the multiple: from chapalang to confluence
Creators: name: Pang, Alvin
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 360201
subject: Creative writing (incl. scriptwriting)

description: The creative writer in Singapore negotiates an environment in which the prevailing mindset is to regard plural variety (in languages, ethnicities, speech patterns, behaviours and domains of activity) as a potential source of social contention, conflict and fracture. In this research, I consider how my varied literary practice might better engage with a sense of the multiple, in testing some of these prescribed bounds and pieties in my practice. My research has led me to discover, follow and explore key currents in my creative practice: from compositional strategies and processes, to my concurrent engagements across professional activities and playful participation in various communities of practice. The findings and creative works that have come out of this process speak to an unsettling of staid norms in the Singaporean context. Based on this context, I experiment with a novel chapalang poetics of polyglot writing; offer ways to reconsider questions of genre distinctions, including the place of the elusive prose poem; surface implications about practising in multiple fields and across domains as a writer leading a multi-careered "double life" (Lahire); and open up fresh lines of thinking about writing as a communal, correspondent and playful endeavour involving what I describe as con-vers-actions.

My observations and reflections about what my writing has been doing bring me to an understanding of creative practice as an energetic gathering and interacting of multiple fluid doings in confluence - characterised by an impulse towards ongoing movement and change. This framing opens up new questions about the materiality and methods involved in creative practice, and suggests directions for future enquiry: such as the entangled and embodied conditions of writing, and its confluential relations with other practitioners. My accounts of some of the currents that constitute my varied, ongoing, evolving practice - demonstrated with reference to writing activities over the course of my practice research - contribute to innovative ways of thinking about practices and processes in the field of creative writing. They will have particular resonance for fellow writers in Singapore and scholars of Singaporean literary practice, but may be of value to any practitioner who has grappled with multiplicity or identifies with a sense of division in their writing life.
Distinguishing effects of area per se and isolation from the sample-area effect for true islands and habitat fragments
Creators: name: MacDonald, ZG
name: Deane, DC
name: He, F
name: Lamb, CT
name: Sperling, FAH
name: Acorn, JH
name: Nielsen, SE
Publisher: name: La Trobe
Year: 2021

description: The island species area relationship (ISAR) is an important tool for measuring variation in species diversity in variety of insular systems, from true-island archipelagoes to fragmented terrestrial landscapes. However, it suffers from several limitations. For example, due to the sample-area effect, positive relationships between species and area cannot be directly interpreted as evidence for deterministic effects of area per se. Additionally, richness-based analyses may obscure species-level responses to area and isolation that may better inform conservation practice. Here, we use random placement models to control for variation in abundance, occupancy and richness associated with the sample-area effect, allowing deterministic effects of area and isolation, and how they vary with species' functional traits, to be resolved using linear mixed effects models. We demonstrate the utility of this approach using a butterfly assemblage persisting on a naturally fragmented landscape of lake islands. The ISAR did not significantly deviate from random placement in relation to island area, isolation or habitat diversity, supporting stochastic assembly consistent with the sample-area effect. Such inferences support the habitat amount hypothesis, which prioritizes preserving the maximum amount of habitat irrespective of its degree of fragmentation. However, species-level analyses demonstrated that species' abundances were significantly lower on both smaller and more isolated islands than what is predicted by the sample-area effect. Moreover, effects of area per se were significantly greater for smaller, less mobile and rare species. Species' occurrences also significantly deviated from predictions of the sample-area effect in relation to island isolation. Thus, our approach illustrates that richness-based analyses not only result in incorrect inferences on mechanisms underlying ISARs, but also obscure important effects of area per se and isolation on individual species that vary with functional traits. We therefore suggest that these effects should not be solely inferred from richness-based analyses, but rather evaluated on a species-by-species basis.
Invasion success and impacts depend on different characteristics in non-native plants
Creators: name: Ni, M
name: deane, david
name: Li, S
name: Wu, Y
name: Sui, X
name: Xu, H
name: Chu, C
name: He, F
name: Fang, S
Publisher: name: La Trobe
Year: 2021

description: Aim: Biological invasions threaten biodiversity globally. Large-scale studies of non-native plant species invasiveness typically focus on identifying ecological differences between naturalized and invasive species that account for their spread from sites of initial establishment (i.e., invasion success). However, invasive species differ widely in the magnitude of their impacts, suggesting the characteristics that favour invasion success might not necessarily predict the consequences of that invasion. Here we test whether those factors that increase the probability of plant species invasion also explain the severity of impacts. Location: China. Methods: We compiled a database of the invasiveness, biogeographic origins, life history traits, and introduction history for 538 non-native plants in China and modelled differences in (a) naturalized and invasive species; (b) the spatial extent of invasion; and, (c) the severity of invasion impacts among successful invaders. Results: Invasion success and the spatial extent of invasion shared similar influencing factors. However, these clearly differed from the predictors of severe invasion impacts. Unintentionally introduced non-native plants with shorter life cycles and longer residence times were more likely to become invasive and to invade a larger area, while taller plants introduced from the Americas tended to have more severe impacts on the native ecosystems of China. Main Conclusions: These results illustrate the different roles of introduction history, biogeographical origin and biological traits in determining the invasion success and spatial extent of invasion versus the severity of invasive species impacts. We suggest that factors associated with evolutionary adaptation and population expansion might determine invasion success and extent, while traits related to the relative competitive ability of invasive species determine the severity of impacts. Identifying specific characteristics of species that distinguish among successful invaders most likely to result in more severe impacts could help with planning more effective interventions.
Riccia cavernosa Raddi
Creators: name: Hugonnot, Vincent
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Plantae
Marchantiophyta
Marchantiopsida
Marchantiales
Ricciaceae
Riccia
Riccia cavernosa

description: Riccia cavernosa Hoffm. emend. Raddi
 SPECIMEN EXAMINED. — France. Corse-du-Sud, Bonifacio, mare temporaire de Musella, 26 IV.2017, 54 m a.s.l., V. Hugonnot s.n.    Remarks
 It was observed within a mediterranean temporary pond of great floristic interest (Lorenzoni & Paradis 1998), in which Eryngium pusillum L. was also found. Both species may share comparable ecological requirements. The associated vegetation is considered to be part of Trifolio-Cynodontion Br.-Bl. & O. Bolòs, 1957. Riccia cavernosa grew directly on wet mud. It seems to suffer from overgrazing of the site which causes severe trampling and direct destruction of vegetation. In the Mediterranean, it was recorded in occasionally to periodically flooded ditch banks, soils depressions and margins of temporary ponds (Jovet-Ast 1986). The thalli observed in Corsica were poorly developed and sterile.
 Riccia cavernosa is a Circumpolar-temperate taxon (Düll 1983). At a world scale it is recorded in northern, western, central and eastern Europe, northern and central Asia, tropical and southern Africa, North, Central and South America and Australasia (Bischler 2004). In the Mediterranean Region its distribution includes Canary Islands, Cape Verde Islands and Madeira in Macaronesia; Balearic Islands, Croatia, France, Italy, Portugal, Sicily and Spain in southern Europe; as well as Algeria, Egypt, Libya, Morocco and Tunisia in northern Africa (Bischler 2004; Patiño Llorente & González Mancebo 2005; Ros et al. 2007). In Mediterranean France, the species is known in the Departments of Pyrénées-Orientales (Hugonnot et al. 2017), Hérault (Crozals 1903) and Bouches-du-Rhône (Hébrard et al. 2014).
description: Published as part of Hugonnot, Vincent, 2019, New records for the bryophyte flora of Corsica, pp. 153-158 in Cryptogamie, Bryologie 20 (14) on page 155, DOI: 10.5252/cryptogamie-bryologie2019v40a14, http://zenodo.org/record/12215529
Riccardia gasparii Reeb & Gradstein 2020, sp. nov.
Creators: name: Reeb, Catherine
name: Gradstein, Robbert
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Plantae
Marchantiophyta
Jungermanniopsida
Metzgeriales
Aneuraceae
Riccardia
Riccardia gasparii

description: Riccardia gasparii Reeb & Gradst. sp. nov.   (Fig. 3 A-E)
DIAGNOSIS. — Dioicous. Thallus very fleshy, unwinged. Axis circular to biconvex, branches with rounded margins. Male branches stalked.
 TYPE. — Madagascar. Alaotra-Mangoro, Vohimana Reserve, Grande Cascade, 18°55’43.6”S 49°29’56.6”E, 849 m, 30. VI.2012, Reeb MTV1246* (holo-, PC [PC 0771050]; iso-, PC [PC 0763876], TAN).
ETYMOLOGY. — Dedicated to Gaspard Reeb-Leurent, born 21/07/2015.
 FURTHER SPECIMENS EXAMINED. — Madagascar. Alaotra-Mangoro, Vohimana Reserve, Grande Cascade, 18°55’43.6”S, 49°29’56.6”E, 849 m, 30.VI.2012, Reeb MTV1257 (PC, TAN); Maromizaha Reserve, 18°58’53.02”S, 48°27’50.1”E, 1002 m, 08.VII.2012, Reeb MTM12124 * (PC, TAN), 18°58’53.10”S, 48°27’51”E, 921 m, 08.VII.2012, Reeb MTM12127A *, MTM12133 *(PC0763885), MTM12134 * (PC0763884, TAN); Analanjirofo, Mananara Nord, E slope of Mahavoho hills, 16°27’S, 49°46.9’47.5”E, 220-300 m, 14.VIII.1998, Pócs & Szabo 9878/W (EGR).
DISTRIBUTION. — Alaotra-Mangoro and Analanjirofo regions of Madagascar.
HABITAT. — On rocks or boulders sometimes covered with a humus layer, in humid evergreen lowland and montane forests, between about 200 and 1000 m.  DESCRIPTION
Dioicous.   Thallus
Dull olive green to green when fresh, green to yellow brown in herbarium, very fleshy, rigid but not leathery (easily breaking when manipulated), to 2 cm long, 1-3-pinnate, not palmate, branches alternate to subopposite, reiterations sometimes present, stolons common, branches mostly wider than the main axis.   Main axis
Irregularly defined to well-defined in mature thalli, width variable, in cross section circular to ellipsoid at the base, circular to biconvex in the middle, 7-9(-16) cells thick, margins obtuse to rounded, not winged, epidermis cells 3-4× smaller than inner cells.   Primary branches
To 7 mm long, often overlapping.   Ultimate branches
Tongue-shaped to oblong, often sinuose (horizontally curved), to 6 mm long and 1.8 mm wide, in cross section plano-convex, 5-6(-7) cells thick, margins obtuse, not winged, epidermis cells 2-3× smaller than inner cells, branch apex rounded.   Mucilage papillae
Apical, not persistent.   Oil bodies
Not seen.   Male branches
On the main axis, solitary, stalked, with a scale-like wing narrower than the axis, the wing crenulate by larger cells.   Female branches
Laterally inserted, straight, bordered by a ciliate, scale-like wing.   Gemmae
Occasionally present, 2-celled.
description: Published as part of Reeb, Catherine & Gradstein, Robbert, 2020, A taxonomic revision of Aneuraceae (Marchantiophyta) from eastern Africa with an interactive identification key, pp. 11-34 in Cryptogamie, Bryologie 20 (2) on pages 22-24, DOI: 10.5252/cryptogamie-bryologie2020v41a2, http://zenodo.org/record/12215441
title: Essays on the organizational economics of the lobbying market
Creators: name: Espinosa, Miguel Andres
Publisher: name: London School of Economics and Political Science (LSE)
Year: 2017
Subjects: subject: H Social Sciences
subject: HB Economic Theory

description: This thesis contains three chapters examining firms’ behaviour and decision making when they seek to influence policies in the US through lobbying activities.
 The first chapter studies the main trade-off that firms face when they face the decision to integrate or outsource knowledge workers. The chapter proposes a model that predicts that firms requiring large firm-specific skills, or low levels of issue-specific skills, or facing a large number of transactions will integrate as opposed to outsource the service provider. Using a newly collected dataset on the US federal lobbying industry, I conduct firm-fixed effect estimations and I find strong evidence supporting the theoretical predictions. To provide further empirical evidence, I exploit a quasi-experiment that the Oil and Gas industry faced: The BP oil spill. The spill increased the issue-specific skills needed to conduct advocacy
 activities and in line with the theory developed in the chapter, I show that the affected industry started using more external, as opposed to internal lobbyists after the oil spill.
 The second chapter studies the effect of a technological upgrade on firms’ vertical integration decision. I use the model proposed in the first chapter to show that a technological shock, introduced by the Open Government Act decreased the cost of acquiring issue-specific skills, which in turn, made firms less likely
 to outsource. Then, I use structural models to measure the magnitude of this technological effect and conduct counterfactual exercises to study the influence that the regulation had on the industry.
 The third chapter studies the relationship between lobbying expenditures and market structure. I show that less and no more concentrated industries spend more on lobbying. To explain this empirical puzzle, I propose a theoretical model that includes the level of excludability in the payoffs. I provide empirical evidence that firms in less concentrated industries tend to lobby for more excludable goods and I show that including this dimension can explain the empirical puzzle. To provide causal evidence, I use national-level mergers that change citylevel market structures. Collecting a new data set of city-level lobbying expenditures, I show that controlling for the level of excludability in the payoffs, more concentrated industries spend more on lobbying efforts.
title: Macchie di leopardo
Creators: name: Prossliner, Lena
Year: 2010

description: Diese Arbeit „Macchie di leopardo – Eine Diskursanalyse über Raumaneignung und Raumzuweisung am Beispiel der Siedlung 'Serenissima' in Padua“ geht anhand eines Fallbeispiels der Frage der Raumnutzung in einem urbanen Umfeld nach. Beschrieben wird die Wandlung, die sich in der Siedlung „Serenissima“ in der Peripherie Paduas (Stadt im Nordosten Italiens), vollzogen hat. Diese Siedlung mit ihren 279 Miniappartements war in den 1970er-Jahren entstanden. Durch verschiedene Faktoren, die in der Arbeit aufgezeigt werden, war die „Serenissima“ Anfang der 1990er-Jahre mehrheitlich von MigrantInnen bewohnt und zudem völlig überbevölkert. Das nicht-Eingreifen von öffentlicher Seite ließ es zu, dass die Siedlung zudem zu einem Drogenumschlagplatz für die gesamte Region Venetien wurde. Mit den Jahren entstand also eine „Raumzuweisung“, die die „Serenissima“ vor allem für die Majoritätsbevölkerung als Drogenumschlagort per exzellent definierte. Diese festgeschriebene Zuschreibung beeinflusste das Leben aller BewohnerInnen der Serenissima, auch derjenigen die mit dem Geschäft des Drogenverkaufs nicht zu tun hatten. Im Jahr 2005 beschloss die Gemeindeverwaltung die Siedlung zu schließen, der Vorgang dauerte bis ins Jahr 2007. In Folge der Schließung vergab der Gemeinderat denjenigen Menschen, die gewissen bürokratischen Auflagen nachkommen konnten, eine Sozialwohnung. Die BewohnerInnen der „Serenissima“, mehrheitlich MigrantInnen, wurde auf verschiedene Stadtviertel verteilt. Anhand von drei Themen – Einwanderung, Stadt und Raum – wird versucht einzelne Diskursebenen, die diesen Prozess geprägt haben, hervorzuheben. Die Berücksichtigung der einzelnen Diskursebenen ermöglicht es interne und externe Faktoren zu berücksichtigen und somit die Ereignisse in der „Serenissima“ in ein urbanes Untersuchungsfeld einzubauen. Der prozessorientierte Charakter dieser Arbeit ist durch eine diachrone Herangehensweise gegeben. Somit wird die Dezentralisierung der Menschen auf die Stadt mit den vorher geschehenen Ereignissen in der „Serenissima“ in Zusammenhang gebracht.
Association of cigarette and electronic nicotine delivery systems use with internalizing and externalizing problems among US adults: Findings from wave 3 (2015–2016) of the PATH study
Creators: name: Kaplan, B
name: Thrul, Johannes
name: Cohen, JE
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Aims: Electronic Nicotine Delivery System (ENDS) use is increasing among US adults. While existing research has demonstrated higher cigarette smoking rates among people with mental health conditions, there is sparse information on the association between ENDS use and mental health such as internalizing and externalizing problems. The aim of this study was to evaluate associations between internalizing and externalizing problems for cigarette only, ENDS only, and dual users, as well as changes in mental health among those groups. Method: We used the U.S. Population Assessment of Tobacco and Health (PATH) Study Wave 3 adult data. Internalizing and externalizing problems were self-reported and assessed via the Global Appraisal of Individual Needs-Short Screener; response options were dichotomized to reflect past 12 months and any lifetime problems. Self-reported changes in mental health over the past 12 months were also assessed. Participants’ tobacco use status was categorized as ENDS only use (n = 618), cigarette only use (n = 6,779), dual use (cigarettes and ENDS) (n = 681), and non-current use (n = 16,515). Results Lifetime and past 12 month internalizing problems were reported by 63.8% (n = 18,706) and 50.4% (n = 15,326), respectively, while lifetime and past 12 months externalizing problems were reported by 63.3% (n = 18,835) and 52.7% (n = 16,005), respectively. Six percent of participants reported worse mental health over the past 12 months. Compared to non-current use of any tobacco product, and adjusting for age, sex, race, education, and household income, those reporting ENDS use only had higher odds of ever (aOR = 1.52; 95%CI: 1.22–1.89) and past 12 months (aOR = 1.49; 95%CI: 1.22–1.84) internalizing, and externalizing problems (aOR = 1.32; 95%CI: 1.04–1.66 and aOR = 1.34; 95%CI: 1.07–1.67, respectively), and higher odds of reporting worse mental health over the past 12 months (aOR = 1.50; 95%CI: 1.05–2.12). Conclusion: Health care providers should be aware that internalizing and externalizing problems, and worsening mental health, are more common among adults who use ENDS, cigarettes, or both of these tobacco products.
Services That Enable Integration And Cross-Linking Across Different Types Of Identifiers And Data Types
Creators: name: Mello, Guilherme De
name: Stocker, Markus
name: Dappert, Angela
name: Dasler, Robin
name: Demeranville, Tom
name: Garza, Kristian
name: Graef, Florian
name: McEntyre, Johanna
name: Schindler, Uwe
Publisher: name: Zenodo
Year: 2017
Subjects: Persistent Identifiers; Project THOR

description: This report summarises progress for disciplinary cross-linking of identifier systems and the results obtained from the perspective of each THOR project partner organisation, in particular disciplinary data repositories. We describe requirements, results, and challenges informed by implementations in the life sciences, earth and environmental sciences, and high-energy physics.
Additional file 3 of Development and validation of the tic score for early detection of traumatic coagulopathy upon hospital admission: a cohort study
Creators: name: Brac, Louis
name: Levrat, Albrice
name: Vacheron, Charles-Hervé
name: Bouzat, Pierre
name: Delory, Tristan
name: David, Jean-Stéphane
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Biotechnology
Cancer
Science Policy
Mental Health
Hematology
Virology
Computational Biology

description: Supplementary file 3 (DOCX 12 kb)
Patients' Preferences for 3 Months vs 6 Months of Adjuvant Chemotherapy for Colon Cancer
Creators: name: Blinman, Prunella
name: Martin, Andrew
name: Jefford, Michael
name: Goldstein, David
name: Boadle, David
name: Morris, Michelle
name: Tebbutt, Niall
name: Aiken, Christine
name: Harkin, Andrea
name: Segelov, Eva
name: Haydon, Andrew
name: Iveson, Tim
name: Stockler, Martin R
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Abstract Background SCOT was an international, randomized phase 3 trial of 3 months vs 6 months of adjuvant chemotherapy with oxaliplatin and a fluoropyrimidine in patients with colorectal cancer. We sought patients’ preferences for 3 months vs 6 months of adjuvant chemotherapy in the SCOT trial. Methods SCOT participants from Australia and New Zealand completed a validated questionnaire (at 3 and 18 months) to elicit the minimum survival benefits judged necessary to make an extra 3 months of adjuvant chemotherapy worthwhile, based on their experience. Standardized hypothetical scenarios used the following baseline survivals (with 3 months of chemotherapy): life expectancies (LE) of 5 years and 15 years and 5-year survival rates (5YS) of 65% and 85%. Results Of the 160 participants, 82 were assigned 3 months adjuvant chemotherapy, and 78 were assigned 6 months. Adjuvant chemotherapy was FOLFOX in 121 (75.6%) and XELOX in 39 (24.4%). Preferences varied substantially and did not differ according to treatment group. The median survival benefits judged necessary to make the extra 3 months of chemotherapy worthwhile were an extra 3 years beyond a LE of 5 years; 3 years beyond a LE of 15 years; 15% beyond a 5YS of 65%; and 5% beyond a 5YS of 85%. Preferences were similar at 3 months and 18 months. Preferences were not predicted by participants’ baseline characteristics. Conclusion Preferences varied substantially, and the benefits many required to warrant an extra 3 months of adjuvant chemotherapy were larger than the benefits of an extra 3 months of chemotherapy calculated in the International Duration Evaluation of Adjuvant Chemotherapy (IDEA) meta-analysis.
title: Schutzwirkung von Safran auf H2O2-induzierte Zellschädigung in HepG2-Zellen
Creators: name: Bilek, Michael
Year: 2010

description: Safran (crocus sativus L.) ist das teuerste Gewürz der Welt. Sein hoher Preis rührt von der Tatsache her, dass die Kultivierung von Hand durchgeführt wird. Wegen seiner Inhaltsstoffe ist crocus sativus L. Gegenstand verschiedener wissenschaftlicher Untersuchungen. In der Vergangenheit wurde einzelnen Inhaltsstoffen antioxidatives Potential und sogar antikanzerogene Wirkungen nachgewiesen. Crocin und Safranal waren in diesem Zusammenhang im Fokus diverser Studien. Von einer Betrachtung isolierter Inhaltsstoffe wurde in dieser Arbeit abgesehen. In der hier durchgeführten in-vitro Studie wurden die zytotoxischen und genotoxischen Wirkungen von Narbenästen und Tepalen des Safrans auf Lebertumorzellen (HepG2-Zellen) getestet. Zusätzlich sollte eine potentielle Schutzwirkung des Safrans auf zuvor mit H2O2 inkubierten Zellen nachgewiesen werden. Zur Bestimmung der Zellvitalität wurde der Trypanblautest angewandt, zur Ermittlung der DNA-Schädigung wurde der Comet-Assay genutzt. Zusammenfassend konnte mit dieser Arbeit eine Tendenz einer erhöhten Zytotoxizität festgestellt werden. Vor allem bei höherer Konzentration von Narbenästen wurde dieses Resultat bestätigt. Sowohl bei den Narbenästen als auch bei den Tepalen kam es zu keiner signifikanten Schutzwirkung vor oxidativem Stress. Aufgrund dieser Beobachtungen lässt sich folgern, dass mittels des hier angewandten wissenschaftlichen Aufbaus dem Safran keine Schutzwirkung, in hoher Konzentration jedoch zytotoxische Tendenzen zugeschrieben werden können.
description: Saffron is the most expensive spice in the world, based on the harvesting condition which is still done by hand. Due to saffron’s ingredients it is focus of ongoing studies. In the past, research could prove that several ingredients exhibit antioxidative and even anticancerogenic properties. In this accomplished in vitro study, cytotoxic and genotoxic effects of saffron’s stigmas and tepals on liver-cancer-cells (HepG2) were compared. In addition, an assumed protective effect on H2O2 incubated cells was determined. The trypanblue-test was used in order to assign cell-vitality. The comet assay was used to prove DNA-damage. Especially at higher concentration of stigmas, a cytotoxic trend was assessed. Neither the stigmas nor the tepals have shown any protection from oxidative stress (H2O2 treated HepG2 cells) in the current study. Based on these observations, using the current scientific design, one cannot expect a protective effect of saffron. However, at high concentrations a cytotoxic tendency was noticed.
Togo: Thorny Transition And Misguided Aid At The Roots Of Economic Misery
Creators: name: Kohnert, Dirk
Publisher: name: Zenodo
Year: 2010
Subjects: Togo
development aid
good governance

description: The parliamentary elections of October 2007, the first free Togolese elections since decades, were meant to correct at least partially the rigged presidential elections of 2005. Western donors considered it as a litmus test of despotic African regimes’ propensity to change towards democratization and economic prosperity. They took Togo as model to test their approach of political conditionality of aid, which had been emphasised also as corner stone of the joint EU-Africa strategy. Empirical findings on the linkage between democratization and economic performance are challenged in this paper because of its basic data deficiencies. It is open to question, whether Togo’s expected economic consolidation and growth will be due to democratization of its institutions or to the improved external environment, notably the growing competition between global players for African natural resources.
Conceptualizing a program aimed at empowering beginning international health science students for a successful transition to university
Creators: name: Cayetano-Penman, Joy
name: Malik, Gulzar
name: Hampton, Kerry
name: Zhong, Yaping
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: International health science students face many challenges at the beginning of their courses, including a lack of awareness of cultural differences, adjusting to academic expectations, communication difficulties, clinical placement challenges, financial pressures, maintaining cultural and religious practices, discrimination, and emotions such as loneliness and being homesick. This study aims to assist beginning international students enrolled in health sciences programs to adapt to university life and achieve academic success by expanding their coping abilities and self- management strategies. A survey approach was used to evaluate the pilot program named EMPOWERMENT. All first-year international students who participated in the EMPOWERMENT program were invited to complete a post-training questionnaire after the program. The results revealed that increased resilience and improved skills to manage stress were the most frequently reported outcomes of the program. In acquiring these important skills, the students valued the opportunity to share their experiences and learn from each other.
title: Grenzüberschreitende öffentliche Übernahmeangebote
Creators: name: Reiter-Germ, Elisabeth Maria Theresia
Year: 2009

description: Die Verflechtung der internationalen Märkte bringt es mit sich, dass auch öffentliche Übernahmeangebote immer öfter als grenzüberschreitende Vorgänge in Erscheinung treten. Europa und die USA können in diesem Zusammenhang zweifellos als wesentliche Rechtsbereiche bezeichnet werden, die allerdings auf dem Gebiet öffentlicher Übernahmen starke Unterschiede bei der Abwägung und dem Ausgleich von Anlegerschutz-, Marktförderungs- und Zielgesellschaftsinteressen aufweisen. Daher bestehen auf dem Gebiet des Übernahmerechts zwischen den US-amerikanischen Normen und den österreichischen Rechtsvorschriften, letztere basierend auf der EU-Übernahmerichtlinie, zahlreiche Unterschiede, die Auswirkungen auf die Verhaltensanforderungen des Bieters und der Zielgesellschaft haben. Im Rahmen der vorliegenden Arbeit wurden ausgewählte wesentliche Bereiche des österreichischen Übernahmerechts untersucht, insbesondere die dem Bieter bzw. der Zielgesellschaft obliegenden Pflichten, und dem US-amerikanischen Recht gegenüber gestellt. Die Gegenüberstellung ergab, dass sich bei Anwendung beider Rechtsordnungen aufgrund von Normenkollisionen bzw. Normenmängeln erhebliche Mehrbelastungen für die Normadressaten ergeben können, da die relevanten Rechtsvorschriften teils völlig unterschiedlichen Inhalt aufweisen, teils strengere Anforderungen stellen oder sogar überhaupt nicht miteinander vereinbar sind. In der Folge wurde die Frage der Schutzwürdigkeit der U.S.-amerikanischen Anleger beleuchtet. Den Abschluss der vorliegenden Arbeit bilden Vorschläge zur möglichen Lösung der Problematik der Normenkollision bzw. des Normenmangels.
description: The interconnection of international markets entails that public offers tend to appear in an increasing number in form of cross-border transactions. Europe and the United States of America can be identified as jurisdictions of major importance in this respect. However, they show significant differences regarding the weighing and conciliation of interests in respect of the target, protection of investors and promotion of markets. Therefore the U.S.-american and the Austrian take-over law, the latter based on the EU directive on take-over bids, show a lot of differences with impacts on the requirements of conduct for target and bidder. This paper elaborates material parts of Austrian compared to U.S.-american take-over law with particular consideration of the duties of taget and bidder. The comparison shows that in case both jurisdictions apply the lack or collision of provisions may lead to a number of considerable additional burdens for the respective concerned party as the relevant provisions may show completely diffenrent content, may ask for stricter requirements or are in contradiction with each other. Subsequently worthiness of protection regarding U.S.-american investor interests are considered. Finally proposals for possible solutions regarding the problems of lack respectively of contradiction of provisions are presented.
Disputa entre un moro y un cristiano: Digital Edition
Creators: name: Jacsont Pauline
Publisher: name: Zenodo
Year: 2024
Subjects: Spanish literature
Digital Edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool eScriptorium (ALTO-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Additional file 1 of Caesarean delivery and neonatal mortality: evidence from selected slums in and around Dhaka city, Bangladesh- A prospective cohort study
Creators: name: Razzaque, Abdur
name: Chowdhury, Razib
name: Mustafa, AHM Golam
name: Billah, Md Arif
name: Naima, Shakera
name: Shafique, Sohana
name: Sarker, Bidhan Krishna
name: Islam, Mohammad Zahirul
name: Kim, Minjoon
name: Jahangir, Margub Aref
name: Matin, Ziaul
name: Ferdous, Jannatul
name: Vandenent, Maya
name: Rahman, Anisur
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
sj-pdf-1-jbr-10.1177_07487304221135916 – Supplemental material for An External Coincidence Model for the Lunar Cycle Reveals Circadian Phase-Dependent Moonlight Effects on Coral Spawning
Creators: name: Komoto, Hideyuki
name: Lin, Che-Hung
name: Nozawa, Yoko
name: Satake, Akiko
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jbr-10.1177_07487304221135916 for An External Coincidence Model for the Lunar Cycle Reveals Circadian Phase-Dependent Moonlight Effects on Coral Spawning by Hideyuki Komoto, Che-Hung Lin, Yoko Nozawa and Akiko Satake in Journal of Biological Rhythms
High resolution continuous field of view thermometry and a model for carbon contamination in focussed electron beam induced deposition of platinum nano-wires
Creators: name: Stavrevski, Daniel
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 510203
subject: Nonlinear optics and spectroscopy

description: The study of temperature on the micro-scale to help understand fundamental material and biological processes is an important scientific frontier today and in the future. Cell respiration is a thermodynamic process that is thought to generate heat as a by-product and can be monitored as a way to track activity and overall health of cell populations. In materials such as semiconductors thermal runaway affects are known to drastically inhibit performance. Having an accurate measure of temperature with high sensitivity and precision in this regime has been reported with continuous sensors, however using these technologies normally requires invasive approaches. We have developed a new approach to sense temperature on the micro-scale in a minimally-invasive manner. Using fabricated lanthanide doped tellurite glass slides as a platform for thermometry, we invoke scanning confocal microscopy (SCM) protocols that enable us to simultaneously collect point-like measurements of temperature and map entire structures over a wide field of view. Using this technique, a proof of concept experiment designed to measure the evaporative cooling of a water droplet is demonstrated. This is then further developed into a coating for novel temperature sensing exposed core fibres. These results pave the way for minimally-invasive marker-free micron scale temperature sensing.

The design of metal nanostructures is important for the sensing of biomolecules, chemicals and semiconductor devices. Patterning an array of metal structures that utilise surface plasmon resonance (SPR) an enhancement effect governed by light-matter interaction has been demonstrated to monitor antibodies, proteins and drugs in-vitro for the diagnosis of serious medical conditions such as Alzheimer's, diabetes and leukemia. A big challenge facing SPR sensors is that the chemical synthesis involved with patterning metal nanostructures requires a flat homogenous surface, limiting their application for in-vivo sensing. Focused electron beam induced deposition (FEBID) is a technique designed for direct the writing of metal nano-wires in novel structures. An inherent problem with FEBID is carbon contamination of structures due to impurities in the precursor gas used in the deposition process, ultimately reducing enhancement effects. We build an effective model for the carbon content in platinum nano-wires using finite domain time difference (FDTD) simulations. With this model we predict the reduction in plasmon enhancement due to carbon deposited in platinum wires during the FEBID process. This model helps us understand important SPR effects that will occur in novel patterned structures, with the ultimate goal of direct writing platinum nano-wires on exposed core fibres for in-vivo diagnosis.