cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Systems biology and inflammation – deciphering multi-omics for translation into the clinic
Creators: name: Zahra Abedi
name: Antonio Del Sol Mesa
Publisher: name: LCSB
Year: 2023

description: Numerous diseases, such as autoimmune disorders or cancer, are associated with complex biological responses known as inflammation. While reductionist strategies provide valuable insight into such mechanisms, revolutionary advances in systems biology attribute significant importance to high-throughput technologies that help integrate multiple omics from genomics to proteomics. This integration offers an intricate yet comprehensive understanding of inflammatory responses. The aim of this review article is to investigate methods and understandings in translational systems biology of inflammation, discuss the broader context of systems biology, study multi-omic approaches, discover clinical applications, and highlight challenges and future directions in the field. We also discuss how multi-omics could improve early diagnosis through predictive models when implemented in clinical contexts.
Sonnenfleckenzeichnung Nr. 116.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.05.1996, 07:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1996

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Global well-posedness on the derivative nonlinear Schrödinger equation revisited
Creators: name: Wu, Yifei
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: primary 35Q55, secondary 35A01

description: As a continuation of the previous work \cite{Wu}, we consider the global well-posedness for the derivative nonlinear Schrödinger equation. We prove that it is globally well-posed in energy space, provided that the initial data $u_0\in H^1(\mathbb{R})$ with $\|u_0\|_{L^2}< 2\sqrtπ$.
description: 8 pages. Some typos are corrected
title: Assessing the suitability of iPSC-derived human astrocytes for disease modeling
Creators: name: Patrycja Mulica
name: Carmen Venegas Maldonado
name: Zied Landoulsi
name: Katja Badanjak
name: Semra Smajic
name: Sylvie Delcambre
name: Jens Christian Schwamborn
name: Rejko Krüger
name: Paul Antony
name: Patrick May
name: Enrico Glaab
name: Anne Grünewald
name: Sandro Lino Cardoso Pereira
Publisher: name: LCSB
Year: 2023

description: Disease modeling with iPSC-derived cultures has proved to be particularly useful, although the selection of an appropriate protocol for a given research question remains challenging. Thus, here, we compared two approaches for the generation of iPSC-derived astrocytes. We phenotyped glia that were obtained using the differentiation protocols by Oksanen or Palm and colleagues, respectively. We employed high-throughput imaging and RNA sequencing to deep-characterize the cultures. Oksanen and Palm astrocytes differ considerably in their properties: while the former cells are more labor-intense in their generation (5 vs 2 months), they are also more mature. This notion was strengthened by data resulting from cell type deconvolution analysis that was applied to bulk transcriptomes from the cultures to assess their similarity with human postmortem astrocytes. Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol, when designing functional or drug discovery studies involving iPSC-derived astrocytes.
Sonnenfleckenzeichnung Nr. 214.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.09.1996, 12:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1996

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
ВЛИЯНИЕ КАЧЕСТВА ЖИЗНИ НА НАУЧНО-ТЕХНИЧЕСКИЙ ПОТЕНЦИАЛ РЕГИОНОВ
Creators: name: ФЕДОТОВ А.А.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: НАУЧНО-ТЕХНИЧЕСКИЙ ПОТЕНЦИАЛ
КАЧЕСТВО ЖИЗНИ
ЧЕЛОВЕЧЕСКИЙ ПОТЕНЦИАЛ
КОРРЕЛЯЦИЯ
РЕГИОН
SCIENTIFIC AND TECHNICAL POTENTIAL
QUALITY OF LIFE
HUMAN POTENTIAL
CORRELATION
REGION

description: Научно-технический потенциал регионов является важнейшей социально-экономической категорией, без развития которой невозможно благополучное существование страны в условиях высокой международной конкуренции. В статье представлен краткий обзор основных методик измерения научно-технического потенциал на региональном уровне. По результатам анализа выделены 8 показателей, характеризующих ресурсную и результативную составляющие научно-технического потенциала регионов. Далее было проведено корреляционное исследование с целью обнаружить тесноту связи между показателями качества жизни и научно-техническим потенциалом регионов. В качестве факторов качества жизни были выбраны 6 показателей, характеризующих благосостояние населения, степень социально-экономического неравенства, уровень занятости и численность студентов. Результаты исследования выявили некоторые функциональные взаимосвязи между исследуемыми категориями. Наиболее сильной оказалась негативная корреляционная связь между безработицей и ресурсными факторами научно-технического потенциала, в частности, денежными затратами на научные исследования и технологические инновации, а также численностью исследователей. Наибольшую корреляционную зависимость от показателей качества жизни, как и ожидалось, показали такие факторы научно-технического потенциала регионов, как затраты на научные исследования и затраты на инновации.
Human myobundle platform for studying the role of Notch signaling in satellite cell phenotype and function
Creators: name: Tsintolas, Nick
name: Hammond, Stewart
name: Helfer, Abbigail
name: Purky, Karly
name: DeLuca, Sophia
name: Khodabukus, Alastair
name: Bursac, Nenad
Publisher: name: Zenodo
Year: 2024

description: This is the data corresponding with the aformentioned manuscipt currently in review. All data is contained in a zip file organized by figure and then panel.
title: Accurate long-read sequencing identified GBA variants as a major genetic risk factor in the Luxembourg Parkinson’s study
Creators: name: Sinthuja Pachchek
name: Zied Landoulsi
name: Lukas Pavelka
name: Claudia Schulte
name: Elena Buena-Atienza
name: Caspar Gross
name: Ann-Kathrin Hauser
name: Dheeraj Reddy Bobbili
name: Nicolas Casadei
name: Patrick May
name: Rejko Krüger
Publisher: name: LCSB
Year: 2023

description: Heterozygous variants in the glucocerebrosidase GBA gene are an increasingly recognized risk factor for Parkinson’s disease (PD). Due to the pseudogene GBAP1 that shares 96% sequence homology with the GBA coding region, accurate variant calling by array-based or short-read sequencing methods remains a major challenge in understanding the genetic landscape of GBA-related PD. We established a novel long-read sequencing technology for assessing the full length of the GBA gene. We used subsequent regression models for genotype-phenotype analyses. We sequenced 752 patients with parkinsonism and 806 healthy controls of the Luxembourg Parkinson’s study. All GBA variants identified showed a 100% true positive rate by Sanger validation. We found 12% of unrelated PD patients carrying GBA variants. Three novel variants of unknown significance (VUS) were identified. Using a structure-based approach, we defined a potential risk prediction method for VUS. This study describes the full landscape of GBA-related parkinsonism in Luxembourg, showing a high prevalence of GBA variants as the major genetic risk for PD. Our approach provides an important advancement for highly accurate GBA variant calling, which is essential for providing access to emerging causative therapies for GBA carriers.
АНАЛИЗ ПРОБЛЕМ БЮДЖЕТНОГО ФЕДЕРАЛИЗМА В РОССИИ
Creators: name: НИКИТЕНКО Ю.В.
name: ЧЕПКАСОВА П.А.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: БЮДЖЕТНЫЙ ФЕДЕРАЛИЗМ
МЕЖБЮДЖЕТНЫЕ ВЗАИМООТНОШЕНИЯ
НАЛОГОВЫЙ КОДЕКС
НАЛОГИ
МЕЖБЮДЖЕТНЫЙ ТРАНСФЕРТ
BUDGET FEDERALISM
INTER BUDGETARY RELATIONS
TAX CODE
TAXES
INTER BUDGETARY TRANSFER

description: В статье рассматриваются проблемы бюджетного федерализма в Российской Федерации. Производится анализ первопричин и последствий. Проводится оценка эффективности существующей в настоящий момент системы, доказывается, что нынешняя практика бюджетного регулирования субъектов РФ и муниципальных образований продолжает оставаться остро нуждающейся в дальнейшем совершенствовании.Приведены данные, позволяющие сделать предположения о перспективах развития межбюджетных взаимоотношений. Рассматриваются теоретические и практические аспекты выбранной темы.
Sonnenfleckenzeichnung Nr. 192.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.08.1996, 07:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1996

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Apulian Gnathia-ware Epichysis
Creators: name: Museum, Centre for Ancient Cultures
Publisher: name: Monash University
Year: 2022
Subjects: Heritage, archive and museum studies not elsewhere classified
Ceramics
Other history, heritage and archaeology not elsewhere classified
Archaeology not elsewhere classified
Archaeology of Europe, the Mediterranean and the Levant
Classical Greek and Roman history

description:
 Apulian Gnathian red-figure Epichysis with a beaked spout and a high strap handle to the rear, sharply angled at the top; a modelled lip, with a ridge decorated with tongues at its inner edge; on each side of the curved handle one female head protome in relief. The spool is decorated with a laurel-leaf band in yellow/cream. The upper face and shoulder are painted with elaborate foliate tendrils and palmette below the handle, volutes on either side, with a central figure of a draped woman offering-bearer seated in profile to the left, her hair pulled back in a sakkos, a cista (large carket) in her raised right. It is decorated with an encircling frieze of ovolo and dot on the shoulder flange; the base of neck shows rays. Stylistic remarks: Subject and execution are exceptionally close to those frequently favoured by the Menzies Group, of the so-called Patera-Ganymede Workshop, active in Apulia during 330–310 BC. Object number: 127.008. Date: 330–310 B.C. Parallels: San Francisco, Fine Arts Museum of San Francisco 2000.89.1; Los Angeles, J. Paul Getty Museum 78.AE.277, 78.AE.350; Princeton, Princeton University Art Museum Y1929-200; Budapest, Museum of Fine Arts 75.41.A (typology and part of the decorative programme); Yale, Yale University Art Gallery 1913.282. References: Bohen, B. et al, From Alexander to Augustus. University of Illinois: Champaign, 1983; Trendall, A. D. and Cambitoglou, A., The Red-Figured Vases of Apulia. Vol. II. Clarendon Press: Oxford, 1982; Wisseman, Sarah U. Corpus Vasorum Antiquorum. Philipp von Zabern: Mainz, 1989, p. 39, Plate 50, 2-3; Mayo and Hamma, Art of South Italy: Vases from Magna Graecia, 1982, pp. 159-160, no. 65; Baur, P. V. C., Catalogue of the Rebecca Darlington Stoddard Collection of Greek and Italian Vases at Yale University, 1st ed., New Haven, Conn.: Yale University Press, 1922, pp. 172-174, no. 282; Beauchamp Walters, H., History of Ancient Pottery: Greek, Etruscan, and Roma, New York: Charles Scribner’s Sons, 1905, p. 179; Baur, P. V. C., Preliminary Catalogue of the Rebecca Darlington Stoddard Collection of Greek and Italian Vases in Yale University, New Haven, Conn.: Yale University Art Gallery, 1914, p. 30, no. 287.Photo by Steve Morton
title: CuFluxSampler.jl: Flexible GPU-accelerated flux samplers for metabolic modeling
Creators: name: Miroslav Kratochvil
name: St. Elmo Wilken
name: Venkata Pardhasaradhi Satagopam
name: Reinhard Schneider
name: Wei Gu
name: Christophe Trefois
Publisher: name: LCSB
Year: 2023

description: Flux sampling is a powerful technique for analyzing the feasible spaces of constraint-based metabolic models. We present CuFluxSampler.jl, a collection of GPU-accelerated flux sampling algorithms that aid quick exploration of complicated constraint-based metabolic models. CuFluxSampler.jl is built upon COBREXA.jl, and shares most of its design features, making it easy to run massively parallel analyses of models subjected to various conditions and constraints. We demonstrate this by exploring and visualizing whole ensembles of metabolic flux samples, showing the ability to build comprehensive flux maps of the model with respect to proteomic and genomic constraints. Finally, we detail the architecture of the CUDA-based implementation and its utilization in HPC platforms.
Sonnenfleckenzeichnung Nr. 71.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.04.1996, 08:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1996

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
ИССЛЕДОВАНИЕ СУЩНОСТИ ФИНАНСОВОГО ПОТЕНЦИАЛА ПРЕДПРИЯТИЯ
Creators: name: ЧЕРНОВОЛ В.В.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: ФИНАНСОВЫЙ ПОТЕНЦИАЛ
ФИНАНСОВЫЕ РЕСУРСЫ
ПРЕДПРИЯТИЕ
ДЕНЕЖНЫЕ ДОХОДЫ
FINANCIAL POTENTIAL
FINANCIAL RESOURCES
ENTERPRISE
CASH INCOME

description: Целью статьи является определение сущности экономической категории «финансовый потенциал предприятия» на основе систематизации, обобщения, критического анализа существующих подходов к трактовке данного понятия. Изучено понятие финансовых ресурсов. Проанализированы подходы к пониманию финансового потенциала. Дано определение финансового потенциала.
Etruscan oil vessel
Creators: name: Museum, Centre for Ancient Cultures
Publisher: name: Monash University
Year: 2022
Subjects: Heritage, archive and museum studies not elsewhere classified
Ceramics
Other history, heritage and archaeology not elsewhere classified
Archaeology not elsewhere classified
Archaeology of Europe, the Mediterranean and the Levant
Historical studies not elsewhere classified
Classical Greek and Roman history
European history (excl. British, classical Greek and Roman)

description:
 A red terracotta black-glazed squat lekythos used to contain oil with a small footed base, a globular body with a curved shoulder, an applied loop handle, a narrow neck that tapers from a broad neck base, and a funnel mouth with flat rim. It bears no decoration. Gifted to Monash by Sir Louis Matheson. Object number: 127.059. Date: 3rd century BCE Parallels: For a similar example with a slender body see Yale, Yale University Art Gallery 1913.462; New York, Metropolitan Museum of Art 41.162.237; References: Baur, P. V. C., Catalogue of the Rebecca Darlington Stoddard Collection of Greek and Italian Vases at Yale University, 1st ed., New Haven, Conn.: Yale University Press, 1922.
 Photo by Steve Morton
Human myobundle platform for studying the role of Notch signaling in satellite cell phenotype and function
Creators: name: Tsintolas, Nick
name: Hammond, Stewart
name: Helfer, Abbigail
name: Purky, Karly
name: Lee, Joonbum
name: DeLuca, Sophia
name: Khodabukus, Alastair
name: Bursac, Nenad
Publisher: name: Zenodo
Year: 2025

description: This is the data corresponding to the published manuscript "Human myobundle platform for studying the role of Notch signalling in satellite cell phenotype and function". All data is contained in a zip file organized by figure and then panel.
Possible Indirect Confirmation of the Existence of Pop III Massive Stars by Gravitational Wave
Creators: name: Kinugawa, Tomoya
name: Inayoshi, Kohei
name: Hotokezaka, Kenta
name: Nakauchi, Daisuke
name: Nakamura, Takashi
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We perform population synthesis simulations for Population III (Pop III) coalescing binary neutron stars (NS-NSs), neutron star - black hole binaries (NS-BHs), and binary black holes (BH-BHs) which merge within the age of the universe. We found that the typical mass of Pop III BH-BHs is $\sim 30\ \rm{M}_{\odot}$ so that the inspiral chirp signal of gravitational waves can be detected up to z=0.28 by KAGRA, Adv. LIGO, Adv. Virgo and GEO network. Our simulations suggest that the detection rate of the coalescing Pop III BH-BHs is $140 (68) \cdot ({\rm SFR}_{\rm p}/10^{-2.5} \rm{M}_{\odot} {\rm yr}^{-1} {\rm Mpc}^{-3}) \cdot {\rm Err}_{\rm sys} ~{\rm events} ~{\rm yr}^{-1}$ for the flat (Salpeter) initial mass function (IMF), respectively, where $\rm SFR_p$ and $\rm Err_{sys}$ are the peak value of the Pop III star formation rate and the possible systematic errors due to the assumptions in Pop III population synthesis, respectively. $\rm Err_{sys}=1$ correspond to conventional parameters for Pop I stars. From the observation of the chirp signal of the coalescing Pop III BH-BHs, we can determine both the mass and the redshift of the binary for the cosmological parameters determined by Planck satellite. Our simulations suggest that the cumulative redshift distribution of the coalescing Pop III BH-BHs depends almost only on the cosmological parameters. We might be able to confirm the existence of Pop III massive stars of mass $\sim 30~\rm M_{\odot}$ by the detections of gravitational waves if the merger rate of the Pop III massive BH-BHs dominates that of Pop I BH-BHs.
description: Accepted for publication in MNRAS
ВНУТРЕННИЙ АУДИТ В РОССИИ СЕГОДНЯ: РАЗВИТИЕ, ПРОБЛЕМЫ, ПЕРСПЕКТИВЫ
Creators: name: ПИВЕНЬ И.Г.
name: ЧЕТЫЗ А.К.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: ВНУТРЕННИЙ АУДИТ
ПРЕДПОСЫЛКИ ФОРМИРОВАНИЯ
ЗАКОНОДАТЕЛЬНОЕ РЕГУЛИРОВАНИЕ
ФУНКЦИИ ВНУТРЕННЕГО АУДИТА
СТАНДАРТЫ РАБОТЫ ВНУТРЕННИХ АУДИТОРОВ
INTERNAL AUDIT
PREREQUISITES FOR FORMATION
LEGISLATIVE REGULATION
INTERNAL AUDIT FUNCTIONS
STANDARDS OF INTERNAL AUDITORS' WORK

description: В статье рассмотрены предпосылки развития внутреннего аудита в России. Выделены основные условия и причины для формирования внутреннего аудита. Определено его значение в деятельности бизнес-структур, в том числе в отношении функций внутреннего контроля и помощи руководству бизнес-структур. Рассмотрены проблемы законодательного регулирования деятельности внутренних аудиторов в России. Рассмотрены основные тенденции в работе внутренних аудиторов, изменения их функций и направлений работы. Выделены основные пользователи результатов работы внутренних аудиторов.
title: Visualization of automatically combined disease maps and pathway diagrams for rare diseases
Creators: name: Piotr Gawron
name: David Hoksza
name: Janet Piñero
name: Maria Pena Chilet
name: Marina Esteban
name: Jose Luis Fernandez-Rueda
name: Vincenza Colonna
name: Ewa Smula
name: Laurent Heirendt
name: François Ancien
name: Valentin Groues
name: Venkata Pardhasaradhi Satagopam
name: Reinhard Schneider
name: Joaquin Dopazo
name: Laura I. Furlong
name: Marek Ostaszewski
Publisher: name: LCSB
Year: 2023

description: Investigation of molecular mechanisms of human disorders, especially rare diseases, require exploration of various knowledge repositories for building precise hypotheses and complex data interpretation. Recently, increasingly more resources offer diagrammatic representation of such mechanisms, including disease-dedicated schematics in pathway databases and disease maps. However, collection of knowledge across them is challenging, especially for research projects with limited manpower. In this article we present an automated workflow for construction of maps of molecular mechanisms for rare diseases. The workflow requires a standardized definition of a disease using OrphaNet or HPO identifiers to collect relevant genes and variants, and to assemble a functional, visual repository of related mechanisms, including data overlays. The diagrams composing the final map are unified to a common systems biology format from CellDesigner SBML, GPML and SBML+layout+renders. The constructed resource contains disease-relevant genes and variants as data overlays for immediate visual exploration, including embedded genetic variant browser and protein structure viewer. We demonstrate the functionality of our workflow on an example of Kawasaki disease. In summary, our work allows for an ad-hoc construction of molecular diagrams combined from different sources, preserving their layout and graphical style, but integrating them into a single resource. This allows to reduce time consuming tasks of prototyping of a molecular disease map, enabling visual exploration, hypothesis building, data visualization and further refinement. The code of the workflow is open and accessible at https://gitlab.lcsb.uni.lu/minerva/automap/.
СОЦИАЛЬНАЯ ОТВЕТСТВЕННОСТЬ ОРГАНИЗАЦИЙ
Creators: name: ШАКИРОВА Н.Н.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: СОЦИАЛЬНЫЕ ОБЯЗАТЕЛЬСТВА
СОЦИАЛЬНАЯ ОТВЕТСТВЕННОСТЬ ОРГАНИЗАЦИЙ
ФОРМАЛИЗОВАННЫЕ ОБЯЗАТЕЛЬСТВА
ОЦЕНОЧНЫЕ ОБЯЗАТЕЛЬСТВА
УСЛОВНЫЕ ОБЯЗАТЕЛЬСТВА
SOCIAL OBLIGATIONS
SOCIAL RESPONSIBILITY OF BUSINESS
FORMALIZED OBLIGATIONS
ESTIMATED OBLIGATIONS
CONTINGENT LIABILITIES

description: В настоящее время «прозрачность» и открытость отчетностей организаций становится все более привлекательным элементом для экономических контрагентов. В статье рассматриваются основные вопросы, посвященные социальной направленности бизнеса. Данная статья делает упор в рассмотрении различных обязательств, возникающих в процессе деятельности организаций. В рамках исследования были изучены финансовые отчетности крупных предприятий России, определены основные тенденции раскрытия данных обязательств и возможные проблемы их отражения.
Sonnenfleckenzeichnung Nr. 161.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.07.1996, 07:15, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1996

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
New N=5,6, 3D gauged supergravities and holography
Creators: name: Chatrabhuti, Auttakit
name: Karndumri, Parinya
name: Ngamwatthanakul, Boonpithak
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study $N=5$ gauged supergravity in three dimensions with compact, non-compact and non-semisimple gauge groups. The theory under consideration is of Chern-Simons type with $USp(4,k)/USp(4)\times USp(k)$ scalar manifold. We classify possible semisimple gauge groups of the $k=2,4$ cases and identify some of their critical points. A number of supersymmetric $AdS_3$ critical points are found, and holographic RG flows interpolating between these critical points are also investigated. As one of our main results, we consider a non-semisimple gauge group $SO(5)\ltimes \mathbf{T}^{10}$ for the theory with $USp(4,4)/USp(4)\times USp(4)$ scalar manifold. The resulting theory describes $N=5$ gauged supergravity in four dimensions reduced on $S^1/\mathbb{Z}_2$ and admits a maximally supersymmetric $AdS_3$ critical point with $Osp(5|2,\mathbb{R})\times Sp(2,\mathbb{R})$ superconformal symmetry. We end the paper with the construction of $SO(6)\ltimes \mathbf{T}^{15}$ gauged supergravity with $N=6$ supersymmetry. The theory admits a half-supersymmetric domain wall as a vacuum solution and may be obtained from an $S^1/\mathbb{Z}_2$ reduction of $N=6$ gauged supergravity in four dimensions.
description: 35 pages, 1 figure
title: Regulation of metabolism and immune response via DJ-1 defines human astrocytic cell fate in Parkinson’s disease and Glioblastoma
Creators: name: Pauline Mencke
name: Jochen Ohnmacht
name: Félicia Jeannelle
name: Adrien J Ries
name: Mónica Miranda De La Maza
name: Mathilde Ullrich
name: François Massart
name: Patrycja Mulica
name: Katja Badanjak
name: Zoé Hanss
name: Arkadiusz Rybicki
name: Paul Antony
name: Sylvie Delcambre
name: Giuseppe Arena
name: Gérald Cruciani
name: Javier Jarazo
name: Floriane Gavotto
name: Christian Jäger
name: Anouk Ewen
name: Maria Pires Pacheco
name: Dirk Brenner
name: Jens Christian Schwamborn
name: Thomas Sauter
name: Lasse Sinkkonen
name: Gunnar Dittmar
name: Ricardo Taipa
name: David Bouvier
name: Johannes Meiser
name: Anne Grünewald
name: Vincenzo Bonifati
name: Michael Platten
name: Rejko Krüger
name: Ibrahim Boussaad
Publisher: name: LCSB
Year: 2023

description: An inverse correlation for the expression of Parkinson´s disease (PD)- and cancer-associated genes has been previously reported. PARK7, encoding DJ-1, was initially identified as an oncogene, but loss of DJ-1 causes early-onset PD. However, it remains elusive how differential DJ-1 levels contribute to opposite cell fates in cancer and PD. Here, we demonstrate specific and differential effects of DJ-1 protein levels in patient-derived cellular models of PD and glioblastoma (GBM) cell lines. Loss of DJ-1 protein in human astrocytes led to impairment of energy metabolism and cell growth associated with an increased immune response upon IL-1β stimulation. In contrast, elevated DJ-1 levels in DJ-1 overexpressing astrocytes and GBM cell lines had the opposite effect. We show that decreased glutathione (GSH) synthesis and therefore increased reactive oxygen species (ROS) levels underly the observed cellular phenotypes, which could be rescued by supplementation with glutathione precursors. Thus, the mechanism by which DJ-1 modulates these phenotypes is the same in both diseases.
Dipole-induced anomalous top quark couplings at the LHC
Creators: name: Tonero, Alberto
name: Rosenfeld, Rogerio
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider direct bounds on the coefficients of higher dimensional top quark dipole operators from their contributions to anomalous top couplings that affect some related processes at the LHC. Several observables are studied. In particular, we incorporate for the first time in this type of analysis the recently measured associated $t \bar{t} V$ production, which is currently the only measured direct observable sensitive to the dipole operator involving the hypercharge field. We perform a Bayesian analysis to derive the $1(2)σ$ confidence level (CL) intervals on these coefficients.
description: 9 pages, 1 figure, 1 table; references added. Version accepted for publication in PRD
Sonnenfleckenzeichnung Nr. 265.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.11.1996, 08:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1996

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: SARS-COV-2 induces dopaminergic neuronal loss in midbrain organoids during extended culture
Creators: name: Javier Jarazo
name: Eveline Santos Da Silva
name: Enrico Glaab
name: Danielle Perez Bercoff
name: Jens Christian Schwamborn
Publisher: name: LCSB
Year: 2023

description: COVID-19 is mainly associated with respiratory symptoms, although several reports showed that SARS-CoV-2 affects the nervous system. We evaluated the effects of infection in prolonged culture of midbrain organoids, showing that the virus induces changes in gene expression, and fragmentation and loss of dopaminergic neurons. Our findings highlight the direct viral-induced damage to midbrain organoids indicating the relevance of assessing the neurological long-term evolution of COVID-19 patients.
Testing the universality of the IMF with Bayesian statistics: young clusters
Creators: name: Dib, Sami
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The universality of the stellar initial mass function (IMF) is tested using Bayesian statistics with a sample of eight young Galactic stellar clusters (IC 348, ONC, NGC 2024, NGC 6611, NGC 2264, $ρ$ Ophiuchi, Chameleon I, and Taurus). We infer the posterior probability distribution function (pPDF) of the IMF parameters when the likelihood function is described by a tapered power law function, a lognormal distribution at low masses coupled to a power law at higher masses, and a multi-component power law function. The inter-cluster comparison of the pPDFs of the IMF parameters for each likelihood function shows that these distributions do not overlap within the $1σ$ uncertainty level. Furthermore, the most probable values of the IMF parameters for most of the clusters deviate substantially from their values for the Galactic field stellar IMF. We also quantify the effects of taking into account the completeness correction as well as the uncertainties on the measured masses. The inclusion of the former affects the inferred pPDFs of the slope of the IMF at the low mass end while considering the latter affects the pPDFs of the slope of the IMF in the intermediate- to high mass regime. As variations are observed in all of the IMF parameters at once and for each of the considered likelihood functions, even for completeness corrected samples, we argue that the observed variations are real and significant, at least for the sample of eight clusters considered in this work. The results presented here clearly show that the IMF is not universal.
description: accepted to MNRAS
Use of Silicon Photomultipliers in ZnS:6LiF scintillation neutron detectors: signal extraction in presence of high dark count rates
Creators: name: Stoykov, A.
name: Mosset, J. -B.
name: Greuter, U.
name: Hildebrandt, M.
name: Schlumpf, N.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We report on the possibility of using Silicon Photomultipliers (SiPMs) to detect the scintillation light from neutron conversion in ZnS:6LiF scintillators. The light is collected by wavelength-shifting fibers embedded into the scintillator. The difficulty of extracting neutron signals in the presence of high dark count rates of the SiPMs is addressed by applying a dedicated processing algorithm to analyze the temporal distribution of the SiPM pulses. With a single-channel prototype detection unit we demonstrate a very good neutron signal extraction at SiPM dark count rates of about 1 MHz.
description: 13 pages, 8 figures; a new section is added, additional discussions and explanations in other sections
The landscape of childcare time burden in the North Central Region
Creators: name: Carrillo-Siller, Ivanna
Publisher: name: Unknown
Year: 2024
Subjects: subject: Community/Rural/Urban Development
subject: Financial Economics
subject: Health Economics and Policy
subject: Labor and Human Capital
subject: childcare
subject: time burden
subject: North Central Region US

description: The importance of childcare in the well-being of families is a key boosting factor of economic prosperity, making it a fundamental public policy issue (Hamm et al., 2019) and the subject of extensive research. However, childcare is unequally distributed across social groups and within family units. Women, low-income households, and minorities disproportionally carry a heavier caregiving responsibility, deeply affecting their employment and income outcomes (Glynn, 2018). In addition, women have been the primary caregivers of children in all types of households and across socioeconomic statuses. In 2020, the COVID-19 pandemic exacerbated the disproportionate childcare burden on women, especially in low educational attainment and low-income households (Liu & Gan, 2024). To evaluate the distribution of the childcare burden across population groups and the current landscape statistics in the North Central Region (NCR), data from the NCR-Stat: Caregiving Survey (Inwood, et al., 2024) are examined.
ВНУТРЕННИЙ КОНТРОЛЬ В ОТНОШЕНИИ КОРПОРАТИВНОГО МОШЕННИЧЕСТВА В ОРГАНИЗАЦИИ
Creators: name: АЛЕКСАНДРОВА П.А.
name: ШАЛЫГИНА М.С.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: КОРПОРАТИВНОЕ МОШЕННИЧЕСТВО
МЕТОДИКА ВЫЯВЛЕНИЯ И ПРЕДУПРЕЖДЕНИЯ НЕПРАВОМЕРНЫХ ДЕЙСТВИЙ
ФАЛЬСИФИКАЦИЯ ОТЧЕТНОСТИ
ЭКОНОМИЧЕСКИЕ ПРЕСТУПЛЕНИЯ
ВНУТРЕННИЙ КОНТРОЛЬ
CORPORATE FRAUD
METHODS TO DETECTION AND WARNING OF LAWLESS ACTIONS
FALSIFICATION OF REPORTS
ECONOMIC CRIMES
INTERNAL CONTROL

description: Для бизнеса в целом наиболее страшным и губительным врагом являются воры, мошенники и взяточники, особенно, если они - те, кому доверяешь больше всего. Как заключенный больше думает о ключе от камеры, чем охранник, так и жулики больше думают об имуществе и активах организации, чем сам собственник. Статья посвящена причинам мошеннических действий в организации, их явным и косвенным признакам, методам предупреждения и выявления в части внутреннего контроля. Практическая значимость исследования заключается в использовании моделей вероятности совершения манипуляций с данными бухгалтерской (финансовой) отчетностью.
Luristan double-ear sword
Creators: name: Museum, Centre for Ancient Cultures
Publisher: name: Monash University
Year: 2022
Subjects: Heritage, archive and museum studies not elsewhere classified
Metals and alloy materials
Other history, heritage and archaeology not elsewhere classified
Archaeology of Asia, Africa and the Americas
Archaeology not elsewhere classified
Historical studies not elsewhere classified
Middle Eastern and North African history
Asian history

description: Long metal sword, possibly from Luristan, with hilt and blade forged in one piece. The double-ear hollow pommel, in crescent shape, at the top of the handle, to prevent the sword slipping from the hand, balance the blade and it is engraved with nervatures in the upper part as a ram’s horn pattern. The narrow grip has a series of lines that would probably have had leather or some other perishable material wrapped around them. This T-hilt sword does not have a guard, just a disc at the end of the guard and, to prevent the hand slipping up the blade a ricasso with two raised segments that embrace the blade. On the blade, the fuller is visible and the almost straight edges are a bit damaged especially in the weak section. The central ridge connects to a blunt point. Peculiarity of this type of swords, the blade is at 90 degrees to hilt. Luristan bronze comes from the province of Lorestan, the modern South-Western Iran. Due to the nomadic nature of the tribes settled in that area, none of the Luristan arms were of great size, since it was required for them to be light and portable. They were commonly used in everyday life and in funerary contexts. Object number: 127.004. Date: 9th–8th century B.C. Parallels: very similar examples with Luristan as findspot Istanbul, Rezan Has Museum (inv. unknown), London, British Museum 123304; compare with 1856,1226.619, 1975,0518; Oxford, Ashmolean Museum AN1966.554. References: Walters, H. B., Catalogue of the Bronzes in the British Museum. Greek, Roman & Etruscan, BMP, London, 1899; very similar sword Moorey, P. R. S., Catalogue of the Persian Bronzes in the Ashmolean Museum, Oxford, 1971, Fig 16. no. 63; Muscarella, O. W., “The Background to the Luristan Bronzes,” in J. Curtis, ed., Bronzeworking Centres of Western Asia c. 1000-539BC., London, 1988, pp. 33-44.; Rehder, J. E., “The decorated iron swords from Luristan: their material and manufacture,” Iran 29, 1991, pp. 13-19; to compare Sestieri, A. M. B. and MacNamara, E., Prehistoric Metal Artefacts from Italy (3500-720 BC) in the British Museum, London: BMP, 2007; Prehistorische Bronzefunde IV. 1, pp. 214–237, Bietti Sestieri 1986, ‘Weapons and Tools’, 4, no. 7, and fig. p. 16.
 Photo by Steve Morton
title: Drivers of change in the temperate-boreal refugium of Cape Breton Highlands National Park
Creators: name: Kosick, Hannah
Publisher: name: Memorial University of Newfoundland
Year: 2023

description: The Acadian-Maritime boreal ecotone of Cape Breton Highlands National Park contains low-elevation temperate species (Wabanaki-Acadian forest), and isolated patches of highland boreal stands at their northern and southern geographic extremes, respectively. The cumulative effects of moose herbivory, continued warming, and an imminent spruce budworm outbreak are expected to increase ecological pressures on the boreal forest, further isolating at-risk species. In addition to these stressors, climate change could induce range shifts of Acadian forests, constraining boreal species distributions. Our study identified if/where Acadian forest range shifts are occurring, examined if moose constrain species expansion, and assessed the availability of species-specific seedbeds. Despite the potential for Acadian range expansion, we did not find evidence of range shifts. Our findings suggest multiple constraints on Acadian forest range expansion, including moose herbivory and lack of suitable Acadian seedbeds at higher altitudes. We observed red maple (Acer rubrum) succession at moose meadows (historic boreal habitat), indicating persistent transitional stages of the boreal forest. Although range shifts have yet to occur, red maple success at moose meadow sites could facilitate Acadian forest expansion if herbivory pressures are reduced. Our research contributes to understanding Acadian-boreal forest dynamics at geographic extremes and establishes a foundation for long-term monitoring.
TOPICAL DRUG DELIVERY SYSTEM: AN OVERVIEW
Creators: name: Manjunath J*, Tanushree C, Suma R
Publisher: name: Zenodo
Year: 2023

description: The drug delivery systems ensure that drugs enter the body and reach their intended place. These systems must consider a variety of factors, ranging from convenience of administration to therapeutic efficacy. Several firms specialise in inventing and marketing drug delivery technologies to pharmaceutical corporations, while others design their own systems. Many of these methods are patented and one-of-a-kind. When a medicine is administered, the dose must be precisely established so that the drug can be utilized by the body, which mandates the use of a drug delivery system with precise dosing capabilities. Drug delivery systems must also consider that how the body metabolizes a drug. Some drugs are destroyed in the digestive tract and hence cannot be administered into the body this way. Others may be toxic in high dosages, necessitating the use of a time release approach to assure patient safety. The application of a medicine to the skin's surface in an absorbable formulation is one way of topical drug administration. Skin patches are one type of topical medicine administration technology. Other treatments include sprays applied to the nose's mucous membranes, inhalation aerosols, eye drops, and lotions applied on the skin. These systems are often simple to use, which appeals to patients. A main purpose of the drug delivery system is to provide the required dosage to the desired location in all situations. Many drugs are available in topical and enteral formulations that may be taken orally or applied directly to the skin because patients prefer painless and uncomplicated methods. Parenteral methods are more common in therapeutic settings, especially for restricted medications, since they provide greater control over how and when drugs are supplied.
KEYWORDS: Skin, Creams, Gels, Pastes, Topical drug delivery system, Ointment.
ВЫБОР АЛЬТЕРНАТИВНОЙ СТРАТЕГИИ РАЗВИТИЯ ДОЧЕРНИХ ПРЕДПРИЯТИЙ
Creators: name: ШТЕФАН Е.В.
name: ШТЕФАН В.И.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: СТРАТЕГИЯ РАЗВИТИЯ
ДОЧЕРНЕЕ ПРЕДПРИЯТИЕ
ИНТЕГРИРОВАННАЯ СТРУКТУРА
ДИВЕРСИФИКАЦИЯ
КОНКУРЕНТНЫЕ ПРЕИМУЩЕСТВА
DEVELOPMENT STRATEGY
SUBSIDIARY
INTEGRATED STRUCTURE
DIVERSIFICATION
COMPETITIVE ADVANTAGES

description: В статье рассматривается подход к выбору альтернативной стратегии развития дочернего предприятия, подконтрольного головной холдинговой компании. Представлена матрица комбинаций сфокусированных стратегий и эталонных стратегий роста. Определено, что дополнительные конкурентные преимущества от вхождения в единый контур интегрированной структуры, предприятия получают за счет установления внутрихолдинговых взаимосвязей в сфере экономики ценообразования, НИОКР, кадрового обеспечения, материально-ресурсного снабжения, логистических цепочек и т.д.
Sonnenfleckenzeichnung Nr. 222.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.09.1996, 07:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1996

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Additional file 2 of Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes
Creators: name: Caron, Barthelemy
name: Patin, Etienne
name: Rotival, Maxime
name: Charbit, Bruno
name: Albert, Matthew L.
name: Quintana-Murci, Lluis
name: Duffy, Darragh
name: Rausell, Antonio
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Figure S1. Principal component analysis of age and sex effects. Figure S2. Manhattan plots and allelic expression of levels of cis-pQTLs. Figure S3. Manhattan plots and allelic expression of levels of trans-pQTLs. Figure S4. Impact of blood-cell fractions on associated protein-SNP pairs statistics.
N-Point Tree-Level Scattering Amplitude in the New Berkovits' String
Creators: name: Gomez, Humberto
name: Yuan, Ellis Ye
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We give a proof by direct computation that at tree level, the twistor-like superstring theory in the pure spinor formalism proposed very recently by Berkovits describes ten-dimensional N=1 super Yang-Mills in its heterotic version, and type II supergravity in its type II version. The Yang-Mills case agrees with the result obtained by Mafra, Schlotterer, Stieberger and Tsimpis. When restricting to gluon and graviton scattering, this new theory gives rise to Cachazo-He-Yuan formula.
description: two footnotes added; version submitted to JHEP
Fluctuation and interaction induced instability of dark solitons in single and binary condensates
Creators: name: Roy, Arko
name: Angom, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We show that the presence of soliton in a single-species condensate, at zero temperature, enhances the quantum depletion sufficient enough to induce dynamical instability of the system. We also predict that for two-species condensates, two Goldstone modes emerge in the excitation spectrum at phase separation. Of these, one is due to the presence of the soliton. We use Hartree-Fock-Bogoliubov theory with Popov approximation to examine the mode evolution, and demonstrate that when the anomalous mode collides with a higher energy mode it renders the solitonic state oscillatory unstable. We also report soliton induced change in the topology of the density profiles of the two-species condensates at phase-separation.
description: arXiv admin note: text overlap with arXiv:1307.5716
ОБ ОСУЩЕСТВЛЕНИИ КОММЕРЧЕСКОЙ ДЕЯТЕЛЬНОСТИ В МАЛОМ БИЗНЕСЕ
Creators: name: ЧЕРНИКОВА В.Е.
name: ШУБИН Г.А.
Publisher: name: Экономика и бизнес: теория и практика
Year: 2020
Subjects: КОММЕРЧЕСКАЯ ДЕЯТЕЛЬНОСТЬ
МАЛЫЙ БИЗНЕС
ПРИНЦИПЫ
ДОХОД
COMMERCIAL ACTIVITY
SMALL BUSINESS
PRINCIPLES
INCOME

description: В статье рассматривается коммерческая деятельность, оказывающая большое влияние на эффективность производства и основные показатели эффективности деятельности компании. Особое внимание в статье уделяется малому бизнесу, который является важным элементом развития предпринимательства в стране. Сделаны выводы о том, что коммерческая деятельность включает в себя основные компоненты ведения бизнеса и позволяет четко выстраивать все бизнес-процессы для достижения поставленных целей, посредством решения определенных задач.