cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Sonnenfleckenzeichnung Nr. 136.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.06.2010, 08:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 200.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.08.2010, 08:15, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 21.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.01.2010, 08:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
The RatioLog Project: Rational Extensions of Logical Reasoning
Creators: name: Furbach, Ulrich
name: Schon, Claudia
name: Stolzenburg, Frieder
name: Weis, Karl-Heinz
name: Wirth, Claus-Peter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Higher-level cognition includes logical reasoning and the ability of question answering with common sense. The RatioLog project addresses the problem of rational reasoning in deep question answering by methods from automated deduction and cognitive computing. In a first phase, we combine techniques from information retrieval and machine learning to find appropriate answer candidates from the huge amount of text in the German version of the free encyclopedia "Wikipedia". In a second phase, an automated theorem prover tries to verify the answer candidates on the basis of their logical representations. In a third phase - because the knowledge may be incomplete and inconsistent -, we consider extensions of logical reasoning to improve the results. In this context, we work toward the application of techniques from human reasoning: We employ defeasible reasoning to compare the answers w.r.t. specificity, deontic logic, normative reasoning, and model construction. Moreover, we use integrated case-based reasoning and machine learning techniques on the basis of the semantic structure of the questions and answer candidates to learn giving the right answers.
description: 7 pages, 3 figures
Sonnenfleckenzeichnung Nr. 9.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.01.2010, 09:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.
Creators: name: Chen, Z.
name: Schwahn, B.C.
name: Genest Jr., J.
name: Laryea, M.D.
name: Rozen, R.
name: Zeisel, S.H.
name: Wendel, U.
name: Castro, C.
name: Garrow, T.
name: Lussier-Cacan, S.
name: Mar, M.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Hyperhomocysteinemia, a proposed risk factor for cardiovascular disease, is also observed in other common disorders. The most frequent genetic cause of hyperhomocysteinemia is a mutated methylenetetrahydrofolate reductase (MTHFR), predominantly when folate status is impaired. MTHFR synthesizes a major methyl donor for homocysteine remethylation to methionine. We administered the alternate choline-derived methyl donor, betaine, to wild-type mice and to littermates with mild or severe hyperhomocysteinemia due to hetero- or homozygosity for a disruption of the Mthfr gene. On control diets, plasma homocysteine and liver choline metabolite levels were strongly dependent on the Mthfr genotype. Betaine supplementation decreased homocysteine in all three genotypes, restored liver betaine and phosphocholine pools, and prevented severe steatosis in Mthfr-deficient mice. Increasing betaine intake did not further decrease homocysteine. In humans with cardiovascular disease, we found a significant negative correlation between plasma betaine and homocysteine concentrations. Our results emphasize the strong interrelationship between homocysteine, folate, and choline metabolism. Hyperhomocysteinemic Mthfr-compromised mice appear to be much more sensitive to changes of choline/betaine intake than do wild-type animals. Hyperhomocysteinemia, in the range of that associated with folate deficiency or with homozygosity for the 677T MTHFR variant, may be associated with disturbed choline metabolism.
title: Review of the Location of VHF Pulses Associated with Lightning Discharge
Creators: name: Kawasaki, Z.
Publisher: name: ONERA
Year: 2012

description: This article gives a brief summary on VHF pulse radiation associated with lightning
discharges and its location. There are two independent techniques: Time of Arrival
and Interferometry. VHF pulses are believed to be emitted during all of the processes
of a lightning discharge. Thus, the mapping of VHF pulses associated with lightning
yields information not only on lightning channel, but also on the charge distribution. On
the other hand, both systems have advantages and disadvantages over each other, and
this article summarizes both principles.
description: Journal Aerospace Lab, Issue 5, December 2012; ISSN: 2107-6596
Synthesis and applications of fused N- and O-heterocyclic systems from nitrodienic building-blocks
Creators: name: BENZI, ALICE
Publisher: name: Universit� degli studi di Genova
Year: 2022

description: N-containing and O-containing heterocycles are widely distributed in natural products essential for life and are often responsible for the pharmaceutical activity of a lot of drugs and lead-compounds. Exploiting the electrophilic nature of functionalized nitrodienic building-blocks, combined with an opportune nuclophile, new protocols for the synthesis of fused N- and O-heterocycles, has been developed. When using 2-aminopyridines or pyrrole as nucleophiles in the reaction with a suitable nitrodienic building block, it is possible to obtain imidazo[1,2-a]pyridines and 7-aryl-6-nitroindoles respectively. The particular substitution of these N-heterocycles was exploited to obtain fused heteropolycles systems: starting from imidazo[1,2-a]pyridines, through a photoinduced 6?-electrocyclization, new fused fluorescent polycycles were synthetized, and their fluorescent properties have been analysed, while performing a classical Cadogan reaction on 7-aryl-6-nitroindoles lead to functionalized pyrrolo[3,2-c]carbazoles. Pyrrolo[3,2-c]carbazoles can react with nitrosoalkenes, leading to the products of alkylation, and this reaction has been studied in collaboration with the Organic Chemistry Group of the University of Coimbra. Since the green approach in organic chemistry is gaining more and more importance, the possibility to use heterogeneous catalysis of Graphene Oxide (GO) in the synthesis of heterocycles, starting from nitrovinylic moieties, has also been investigated. Finally, from the reaction between some particular nitrostilbenes and 2-naphthtol or 8-hydroxyquinoline, it was possible to synthetize a small library of dihydronaphtho- and naphthofuran derivatives. Naphthofurans obtained shown a good fluorescence, and their nature of diarylethenes made them promising substrates for a 6?-electrocyclization, with further expansion of the aromatic system, and the formation of a new benzenic ring, leading to new fused O-heterocyclic systems.
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro.
Creators: name: Mar, M.H.
name: Fisher, M.C.
name: Zeisel, S.H.
name: Sadler, T.W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: A role for choline during early stages of mammalian embryogenesis has not been established, although recent studies show that inhibitors of choline uptake and metabolism, 2-dimethylaminoethanol (DMAE), and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3), produce neural tube defects in mouse embryos grown in vitro. To determine potential mechanisms responsible for these abnormalities, choline metabolism in the presence or absence of these inhibitors was evaluated in cultured, neurulating mouse embryos by using chromatographic techniques. Results showed that 90%-95% of 14C-choline was incorporated into phosphocholine and phosphatidylcholine (PtdCho), which was metabolized to sphingomyelin. Choline was oxidized to betaine, and betaine homocysteine methyltransferase was expressed. Acetylcholine was synthesized in yolk sacs, but 70 kDa choline acetyltransferase was undetectable by immunoblot. DMAE reduced embryonic choline uptake and inhibited phosphocholine, PtdCho, phosphatidylethanolamine (PtdEtn), and sphingomyelin synthesis. ET-18-OCH3 also inhibited PtdCho synthesis. In embryos and yolk sacs incubated with 3H-ethanolamine, 95% of recovered label was PtdEtn, but PtdEtn was not converted to PtdCho, which suggested that phosphatidylethanolamine methyltransferase (PeMT) activity was absent. In ET-18-OCH3 treated yolk sacs, PtdEtn was increased, but PtdCho was still not generated through PeMT. Results suggest that endogenous PtdCho synthesis is important during neurulation and that perturbed choline metabolism contributes to neural tube defects produced by DMAE and ET-18-OCH3.
L'artefice nel pensiero francescano
Creators: name: SALVESTRINI, AMALIA MARIA SOFIA
Publisher: name: Universit� degli studi di Genova
Year: 2022

description: Il presente lavoro si propone d?interrogare alcuni testi premoderni, quelli del Medioevo francescano in particolare, per comprendere come la figura dell?artefice e l?esperienza della produzione artificiale sono stati oggetto di una riflessione che potremmo chiamare ?estetica?, prima della nascita dell?estetica in quanto disciplina. Il fenomeno della poiesis nel Medioevo � pensato attraverso una distinzione fondamentale, ossia quella tra artefice umano e artefice divino. Sulla base di questa distinzione, la poiesis non � considerata come una creazione a partire dal nulla da parte di qualcuno che, fuori da un ordine cosmico e metafisico, obbedisce alle sole leggi che si d� in modo autonomo. Al contrario, pensare la poiesis in questo periodo implica avere coscienza dell?ordine nel quale l?artefice si pone, dei criteri ai quali egli si conforma e che sono l?espressione delle scelte originarie per mezzo delle quali Dio artefice cre� il mondo. La riflessione francescana sull?artefice � qui studiata a partire da un corpus di testi di Bonaventura da Bagnoregio, Pietro di Giovanni Olivi, Giovanni Duns Scoto e Guglielmo di Ockham. Nel Volume 1 si studia la costituzione filosofica dell?artefice. In primo luogo, si osserva la sua genesi attraverso fonti scritturistiche, filosofiche e retoriche (Parte I). In secondo luogo, si ricostruiscono le prospettive francescane sull?artefice attraverso l?articolazione dell?attivit� poietica in progetto, opera e fruizione (Parte II). Nell?ultima parte, dedicata al passaggio dall?artefice all?artista (Parte III), ci si interroga, alla luce del percorso effettuato, sulla possibilit� di ?estetiche? francescane, cos� come sul passaggio da queste all?arte francescana. Infine, si aprono alcune linee di ricerca sulle possibili relazioni tra l?artefice francescano e le teorie artistiche rinascimentali. Nel Volume 2 della dissertazione (Appendice. Le parole. Lo spazio semantico dell?artefice) si mette a disposizione la documentazione commentata del corpus di testi dei quattro autori francescani.
Impact assessment of harmonics emissions on active distribution network planning and operation
Creators: name: Nduka, Onyema Sunday
Publisher: name: Imperial College London
Year: 2018

description: Modern distribution networks (DNs) now have increased penetration of switching electronic loads and grid-integrated renewable distributed generators (RDGs) like photovoltaics (PVs). The trend of RDG integration has being promoted by the quests for the reduction of greenhouse gas emissions whilst growth in the use of electronically controlled devices is facilitated by the increasing demand for automation in many facets of life. While the integration of these switching electronic devices into the power grid might be advantageous to the customers, distribution network operators (DNOs) worry that high penetration of these devices might challenge their network operations. This is because the power conditioners of the above network components emit harmonic currents and voltages which affect the utility equipment by way of overheating, mal-operation and damage. Moreover, past DNs had the planning and operational philosophy that the harmonics emission levels were negligible. With the increased presence of these RDG converters and nonlinear loads, the assumption of infinitesimally small harmonics level need to be re-evaluated. Consequently, this PhD research investigated the impacts of harmonics pollution from power converters of PVRDGs and switching electronic devices on active DN performance indices such as network losses. Firstly, advanced harmonic domain models of single and three-phase PVRDGs adequate for representing the actual interaction between DNO network and the switching devices were developed. Next, detailed advanced harmonic model of typical DNs has evolved from this research. These improved models have been used to study harmonic pollution challenges such as harmonics induced electrical losses and resonance phenomenon in distribution systems with high penetration of PVRDGs and switching loads. The constraints imposed by network unbalance and harmonics emission on exploiting PVRDGs for maximizing loss reduction benefits have also been analyzed. The technical insights gained from this research work are beneficial to utilities in the design and planning of their system operation.
Bridging the Gap between an Isolated Nanochannel/pore System and Communicating Multipore Heterogeneous Membrane System
Creators: name: Green, Yoav
name: Park, Sinwook
name: Yossifon, Gilad
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: To bridge the gap between single/isolated pore systems to multi-pore systems, such as membranes/electrodes, we studied an array of nanochannels with varying interchannel spacing that controlled the degree of channel communication. Instead of treating them as individual channels connected in parallel or an assembly like a homogeneous membrane, this study resolves the pore-pore interaction. We found that increased channel isolation leads to current intensification whereas at high voltages electro-convective effects control the degree of communication via suppression of the diffusion layer growth
description: 4 figures,submitted to Phys. Rev. E
Sonnenfleckenzeichnung Nr. 19.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.01.2010, 14:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Molecular determinants of IBDV pathogenesis and modulation of the host innate response
Creators: name: Dulwich, Katherine Louise
Publisher: name: Imperial College London
Year: 2019

description: Viruses are known to interact with the innate immune pathways and, in some cases, strains that differ in virulence are known to interact with these pathways in different ways. This thesis aimed to directly compare IBDV strains of differing virulence to determine key interactions with the innate immune response that may contribute to disease outcome. Infection of chicken B cells with the very virulent s UK661 strain, suppressed type I IFN responses compared to both infection with the cell-adapted IBDV strain, D78 in primary bursal cells, and infection with the classical strain, F52/70 in DT40 cells. Birds infected with UK661 also had down-regulated type I IFN and pro-inflammatory responses in the bursa of Fabricius (BF), compared to infection with F52/70. No difference in the peak virus titres was detected in the BF or spleen, although UK661 reached higher titres in the caecal tonsils than F52/70. Increased type I IFN production following F52/70 infection coincided with a reduced mortality in these birds, indicating a protective role of this immune response. The UK661 VP4 protein was found to suppress IFNβ production in vitro compared to the F52/70 VP4, which instead suppressed Mx1 production, indicating that the IBDV VP4 from different strains impairs either IFN production or signalling pathways. Upon knocking out the protease function of UK661 VP4, IFNβ production remained suppressed, and multiple amino acids are likely responsible for the different phenotype between strains. This work demonstrates that UK661 and F52/70 have strain-specific differences in their interactions with the innate immune response, mediated by the VP4 protein, therefore differences in this protein between strains may contribute to virulence. This information could be useful in the development of recombinant rationally designed live attenuated IBDV vaccines, by generating a vvIBDV backbone containing a VP4 from a classical or cell-adapted strain, as a vaccine candidate.
Altered mitochondrial function and overgeneration of reactive oxygen species precede the induction of apoptosis by 1-O-octadecyl-2-methyl-rac-glycero-3-phosphocholine in p53-defective hepatocytes
Creators: name: Salganik, R.I.
name: Craciunescu, C.N.
name: Albright, C.D.
name: Vrablic, A.S.
name: Zeisel, S.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: The mechanism of induction of apoptosis by the novel anti-cancer drug 1-O-octadecyl-2-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) was investigated in p53-defective SV40 immortalized rat hepatocytes (CWSV1). Exposure to 12 uμM ET-18-OCH3 for 36 h induced apoptosis as determined using classical morphological features and agarose gel electrophoresis of genomic DNA. Increased levels of reactive oxygen species (ROS) were detected spectrophotometrically using a nitroblue tetrazolium (NBT) assay in cells treated with ET-18-OCH3. Both the increased generation of ROS and the induction of apoptosis were inhibited when cells were treated concurrently with ET-18-OCH3 in the presence of the antioxidant α-to-copherol. Similar results were achieved when cells were switched acutely to choline-deficient (CD) medium in the presence of the antioxidant. The possible role of mitochondria in the generation of ROS was investigated. Both ET-18-OCH3 and CD decreased the phosphatidylcholine (PC) content of mitochondrial and associated membranes, which correlated with depolarization of the mitochondrial membrane as analyzed using 5,5′,6,6′-tetramethylbenzimidazolcarbocyanine iodide (JC-1), a sensitive probe of mitochondrial membrane potential. Rotenone, an inhibitor of the mitochondrial electron transport chain, significantly reduced the intracellular level of ROS and prevented mitochondrial membrane depolarization, correlating with a reduction of apoptosis in response to either ET-18-OCH3 or CD. Taken together, these results suggest that the form of p53-independent apoptosis induced by ET-18-OCH3 is mediated by alterations in mitochondrial membrane PC, a loss of mitochondrial membrane potential, and the release of ROS, resulting in completion of apoptosis.
Robust data cleaning procedure for large scale medium voltage distribution networks feeders
Creators: name: Huyghues-Beaufond, Nathalie
Publisher: name: Imperial College London
Year: 2019

description: Relatively little attention has been given to the short-term load forecasting problem of primary substations mainly because load forecasts were not essential to secure the operation of passive distribution networks. With the increasing uptake of intermittent generations, distribution networks are becoming active since power flows can change direction in a somewhat volatile fashion. The volatility of power flows introduces operational constraints on voltage control, system fault levels, thermal constraints, systems losses and high reverse power flows. Today, greater observability of the networks is essential to maintain a safe overall system and to maximise the utilisation of existing assets. Hence, to identify and anticipate for any forthcoming critical operational conditions, networks operators are compelled to broaden their visibility of the networks to time horizons that include not only real-time information but also hour-ahead and day-ahead forecasts. With this change in paradigm, progressively, large scales of short-term load forecasters is integrated as an essential component of distribution networks' control and planning tools. The data acquisition of large scale real-world data is prone to errors; anomalies in data sets can lead to erroneous forecasting outcomes. Hence, data cleansing is an essential first step in data-driven learning techniques. Data cleansing is a labour-intensive and time-consuming task for the following reasons: 1) to select a suitable cleansing method is not trivial 2) to generalise or automate a cleansing procedure is challenging, 3) there is a risk to introduce new errors in the data. This thesis attempts to maximise the performance of large scale forecasting models by addressing the quality of the modelling data. Thus, the objectives of this research are to identify the bad data quality causes, design an automatic data cleansing procedure suitable for large scale distribution network datasets and, to propose a rigorous framework for modelling MV distribution network feeders time series with deep learning architecture. The thesis discusses in detail the challenges in handling and modelling real-world distribution feeders time series. It also discusses a robust technique to detect outliers in the presence of level-shifts, and suitable missing values imputation techniques. All the concepts have been demonstrated on large real-world distribution network data.
Sonnenfleckenzeichnung Nr. 7.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.01.2010, 10:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
De Newton à Boltzmann et Einstein: validation des modèles cinétiques et de diffusion
Creators: name: Golse, François
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 35Q20, 82A70 (Primary) 35Q70, 82B40, 82C22 (Secondary)

description: The kinetic theory of Maxwell and Boltzmann has been the subject of major scientific controversies. The alleged incompatibility between the reversible nature of the equations of classical mechanics and the increase of entropy, which, in the kinetic theory of gases, is a mathematical property of the Boltzmann equation known as the H Theorem, was one of the most basic arguments against the validity of kinetic theory. About a century later, in 1974, O. Lanford proposed a strategy to prove that the Boltzmann equation describes a particular asymptotic limit of Newton's equations of classical mechanics for a system made of a large number N of spherical particles interacting by elastic collisions. A recent work by I. Gallagher, L. Saint-Raymond and B. Texier completes Lanford's proof and extends it to the case where the interaction between particles is given by a short range potential. In a later article, T. Bodineau, I. Gallagher and L. Saint-Raymond study the dynamics of a tagged particle among N other identical particles in the same asymptotic regime, and prove the validity of the linear Boltzmann equation on arbitrary large periods of time as N tends to infinity. Using classical results on the asymptotic theory of the linear Boltzmann equation, the same authors prove that the stochastic process known as the "Brownian motion" describes a particular limit of the deterministic dynamics of interacting particles.
description: 39 pages, in French. Bourbaki Seminar, March 2014
Sonnenfleckenzeichnung Nr. 60.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.03.2010, 08:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 116.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.05.2010, 13:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Choline deficiency induces apoptosis in primary cultures of fetal neurons
Creators: name: Yen, C.-L.E.
name: Fernandes, A.
name: Zeisel, S.H.
name: Mar, M.-H.
name: Meeker, R.B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Treatment of rats with choline during brain development results in long-lasting enhancement of spatial memory whereas choline deficiency has the opposite effect. Changes in rates of apoptosis may be responsible. We previously demonstrated that choline deficiency induced apoptosis in PC12 cells and suggested that interruption of cell cycling due to a decrease in membrane phosphatidylcholine concentration was the critical mechanism. We now examine whether choline deprivation induces apoptosis in non-dividing primary neuronal cultures of fetal rat cortex and hippocampus. Choline deficiency induced widespread apoptosis in primary neuronal cells, indicating that cells do not have to be dividing to be sensitive to choline deficiency. When switched to a choline-deficient medium, both types of cells became depleted of choline, phosphocholine and phosphatidylcholine, and in primary neurons neurite outgrowth was dramatically attenuated. Primary cells could be rescued from apoptosis by treatment with phosphocholine or lysophosphatidylcholine. As described previously for PC12 cells, an increase in ceramide (Cer) was associated with choline deficiency-induced apoptosis in primary neurons. The primary neuronal culture appears to be an excellent model to explore the mechanism whereby maternal dietary choline intake modulates apoptosis in the fetal brain.
Sonnenfleckenzeichnung Nr. 48.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.03.2010, 11:00, erstellt von Anna Cairati
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502218) Catherine Gentle Leitch
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sonnenfleckenzeichnung Nr. 166.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.07.2010, 07:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
MORPH: A Reference Architecture for Configuration and Behaviour Self-Adaptation
Creators: name: Braberman, Victor
name: D'Ippolito, Nicolas
name: Kramer, Jeff
name: Sykes, Daniel
name: Uchitel, Sebastian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: An architectural approach to self-adaptive systems involves runtime change of system configuration (i.e., the system's components, their bindings and operational parameters) and behaviour update (i.e., component orchestration). Thus, dynamic reconfiguration and discrete event control theory are at the heart of architectural adaptation. Although controlling configuration and behaviour at runtime has been discussed and applied to architectural adaptation, architectures for self-adaptive systems often compound these two aspects reducing the potential for adaptability. In this paper we propose a reference architecture that allows for coordinated yet transparent and independent adaptation of system configuration and behaviour.
Sonnenfleckenzeichnung Nr. 124.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.06.2010, 08:45, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 217.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.09.2010, 07:15, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502221) James Younger
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Opposing Regulation of Choline Deficiency-induced Apoptosis by p53 and Nuclear Factor κB
Creators: name: Zeisel, S.H.
name: Holmes-McNary, M.Q.
name: Baldwin Jr., A.S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: We have previously shown that fetal rat brain cells, preneuronal (PC12), and hepatocyte (CWSV-1) cells undergo apoptosis during choline deficiency (CD). The PC12 and epithelial cell culture models were used to determine the molecular mechanism by which CD induces apoptosis. Our data indicate that CD leads to both growth arrest and apoptosis in a subpopulation of cells, which correlate with the up-regulation of the tumor suppressor protein p53 and concurrent up-regulation of the cyclin-dependent kinase-inhibitor p21 WAF1/CIP1. Additionally, CD induced both a G1/S and a G2/M arrest. Transient transfection of a dominant negative p53 (p53DN) construct into PC12 cells, which inhibited endogenous p53 activation, significantly reduced the induction of apoptosis associated with CD. Interestingly, CD also induced the persistent activation of the transcription factor NF-κB. Activation of NF-κB has been shown to promote cell survival and proposed to antagonize p53. Consistent with this, expression of a superrepressor form of IκBα (SR-IκBα) that functions to strongly inhibit NF-κB activation, profoundly enhanced cell death during CD. In summary, these results suggest that the effects of CD on apoptosis and subsequent cell survival are mediated through two different signaling pathways, p53 and NF-κB, respectively. Taken together, our data demonstrates the induction of opposing mechanisms associated with nutrient deficiency that may provide a molecular mechanism by which CD promotes carcinogenesis.
Sonnenfleckenzeichnung Nr. 248.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.10.2010, 08:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Polarity Asymmetry in Lightning Leaders: the Evolution of Ideas on Lightning Behavior from Strikes to Aircraft
Creators: name: Williams, E.
name: Heckman, S.
Publisher: name: ONERA
Year: 2012

description: This study is concerned with outstanding questions on the mechanism of lightning
and its theoretical treatment as a bidirectional leader. Previous studies of lightning
strikes to aircraft are reviewed to highlight the key physical phenomena: the simultaneous
action of both positive and negative leaders, the frequent tendency for electrical
current in certain channels to cut-off abruptly, and the subsequent tendency for recoil
leaders to initiate in these previously cut-off channels to establish a new stroke in the
flash.
description: Journal Aerospace Lab, Issue 5, December 2012; ISSN: 2107-6596
Heat equation on a network using the Fokas method
Creators: name: Sheils, N. E.
name: Smith, D. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35C15 (primary), 35K05, 35K20 (secondary)

description: The problem of heat conduction on networks of multiply connected rods is solved by providing an explicit solution of the one-dimensional heat equation in each domain. The size and connectivity of the rods is known, but neither temperature nor heat flux are prescribed at the interface. Instead, the physical assumptions of continuity at the interfaces are the only conditions imposed. This work generalizes that of Deconinck, Pelloni, and Sheils, 2014, for heat conduction on a series of one-dimensional rods connected end-to-end to the case of general configurations.
description: 21 pages, 8 figures
Journey Through the Universe Celebrates 16 Years (and Counting!)
Creators: name: Harvey, Janice
Publisher: name: Zenodo
Year: 2020
Subjects: Journey Through the Universe

description: The Journey Through the Universe (Journey) program celebrated 16 continuous years of astronomy education in Hawai'i in March of this year, with the support of community businesses and over 60 local and national astronomy professionals, NOIRLab's flagship outreach program, led by the Communications, Education & Engagement (CEE)-Hawai'i team.
description: Issue 1, June 2020
Modulated magnetic and structural states, Dynamics and functionalities
Creators: name: FOGGETTI, FRANCESCO
Publisher: name: Universit� degli studi di Genova
Year: 2021

description: The aim of this thesis is to describe a number of materials that have attracted interest due to their magnetic, electric or structural properties with the use of generalized models. In hexagonal multiferroic LuFeO3 the study of the magnetic excitations in the material reveals the presence of elusive topological objects (i.e. effective magnetic monopoles and toroidal moments) not previously reported as well ad the non-reciprocal character of particular magnons in the material. The model and the results can be generalized to the class of hexagonal multiferroics. In the case of TbMnO3 we analyze the excitation spectrum of a cycloidal spin system that exhibit improper ferroelectricity. The results reveal that soft electromagnons have a large contribution, due to domain wall-localized modes, to the static dielectric constant of the material and, in general, of the cycloidal systems. A study of the response of GaV4S8 to photoexcitation is performed through atomistic spin dynamics simulations. Thermal properties of GaV4S8 are discovered to be related to the magnetic phases of the material due to the changing magnon transport properties of different magnetic phases. A change of the order of 2 in the thermal conductivity is observed in the transition from cycloidal to ferromagnetic phases A study of improper ferroelectricity in hybrid organic-inorganic perovskites is performed by using a Landau type symmetry breaking theory. The theory shows a rich phase diagram and the presence of nested domain walls. The theory describes a molecular ordering mechanism as a possible explanation for weak improper ferroelectricity observed in NH2(CH3)2Fe(COOH)3. The decade-long problem of the stripe ordering in IrTe2 is addressed. The existing observations of different striped phases in the material are reproduced in this study through a combination of first principle calculations and a phenomenological model. The same model predicts a phase diagram for the dimerized phases in the shape of a Devil's Staircase. This result partially fills a gap in the knowledge about IrTe, up to date no exhaustive explanation is known for the dimerization mechanism, and no other information on the dimerized phase diagram was available aside of the results reproduced in this work. The essence of this work is that minimalistic models and general considerations about energy and symmetries are powerful tools to describe quite diverse problems. This thesis address the importance of the excitations in the properties of certain materials and points out features that have not been previously reported in literature.
Choline deficiency-induced apoptosis in PC12 cells is associated with diminished membrane phosphatidylcholine and sphingomyelin, accumulation of ceramide and diacylglycerol, and activation of a caspase
Creators: name: Mar, M.-H.
name: Yen, C.-L.E.
name: Zeisel, S.H.
Publisher: name: FASEB
Year: 1999

description: It is not well appreciated that nutritional status can modulate apoptosis, a process that eliminates unwanted or damaged cells. Choline is an essential nutrient, and its absence induces apoptosis. When PC12 cells were cultivated in a choline-free medium, apoptosis was induced (27.4% of cells apoptotic at 72 h as compared to 4.4% in control medium). In choline-free medium at 72 h, there was a 49% decrease in phosphatidylcholine concentration (P<0.01) and a 34% decrease in sphingomyelin concentration (P<0.01); however, there was no change in phosphatidylethanolamine concentration. Before detecting increased apoptosis in choline-deficient cells, we measured a significant increase in ceramide (218% control) and diacyglycerol (155% control) concentrations. The addition of a cell-permeable ceramide to cells in control medium induced apoptosis; however, adding a cell-permeable diacyglycerol did not induce apoptosis. Caspase is a common mediator of apoptosis, and choline deficiency-induced apoptosis was prevented completely by replacing choline or adding a caspase inhibitor into the medium within 48 h of initial choline deprivation. In those cells rescued by replacing choline at 36 h, the concentrations of phosphatidylcholine, sphingomyelin, ceramide, and diacyglycerol returned to levels of control cells. In those cells rescued by adding a caspase inhibitor at 36 h, the concentrations of sphingomyelin and ceramide returned to control levels, but the concentrations of phosphatidylcholine and diacyglycerol did not return to normal. We propose that availability of dietary factors (choline in this model) can modulate apoptosis. Mechanisms that we identify using this model may help us to explain why dietary choline influences brain development.
Sonnenfleckenzeichnung Nr. 141.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.06.2010, 09:00, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)