cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Current data in Greek children indicate decreasing trends of obesity in the transition from childhood to adolescence; results from the EYZHN (National Action for Children’s Health) program
Creators: name: Tambalis, Konstantinos D
name: Panagiotakos, Demosthenes B
name: Psarra, Glykeria
name: Sidossis, Labros S
Publisher: name: Department of Health Science - University of Genoa
Year: 2018

description: Introduction: The aim of the study was to present the most recent estimates of obesity (total and central) prevalence in Greek children and risk factors associated with.

Methods: Population data derived from a yearly, school-based health survey carried out in 2015 on 336,014 (51% boys) children aged 4 to 17 years old from almost 40% of all schools of primary and secondary education in Greece. Anthropometric and physical fitness measurements were obtained by trained investigators. Dietary habits, physical activity status, sedentary activities and sleeping hours were assessed through self-completed questionnaires. The gender and age specific Body Mass Index (BMI) cut-off points were used in order to define BMI groups.

Results: The prevalence of overweight and obesity in the whole population was 22.2% and 9.0% in boys and 21.6% and 7.5% in girls, respectively. Obesity presented decreasing trends in the transition from childhood to adolescence. Central obesity was diagnosed in 95.3% and 93.5% of the simple obese boys and girls, respectively, in almost two to three of overweight children (68.6% of boys and 64.3% of girls), and in 12% of normal weight children. Age, physical fitness, low adherence to Mediterranean diet, insufficient sleeping hours, inadequate physical activity levels and increased screen time were all associated with higher odds of total and central obesity.

Conclusions: Serious and urgent actions need to be taken from public health policy makers in order not only to prevent a further increase in obesity rates but, more important, to treat obesity and/or the obesity associated co-morbidities.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
Genetic characterization of varicella-zoster and HIV-1 viruses from the cerebrospinal fluid of a co-infected encephalitic patient, Ghana.
Creators: name: El-Duah, Philip
name: Sylverken, Augustina Angelina
name: Owusu, Michael
name: Amoako, Yaw Ampem
name: Yeboah, Richmond
name: Gorman, Richmond
name: Nyarko-Afriyie, Emmanuella
name: Schneider, Julia
name: Jones, Terry C
name: Bonney, Joseph
name: Adade, Titus
name: Yeboah, Eric Smart
name: Binger, Tabea
name: Corman, Victor Max
name: Drosten, Christian
name: Phillips, Richard Odame
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Case Report
Clinical Virology
Varicella-zoster virus
Chickenpox
HIV
Coinfection
Encephalitis
Ghana

description: Funder: Charité - Universitätsmedizin Berlin (3093)
description: BACKGROUND: Encephalitis is a serious disease of the brain characterized by prodromal and specific neurological symptoms. HIV infections offer opportunistic viruses, such as Varicella-zoster virus (VZV), the chance to cause encephalitis in patients. There is a lack of information on the genetic diversity of VZV in Ghana and other parts of Africa which requires sequencing and characterization studies to address. The active evolution of HIV-1 in West Africa also requires continuous surveillance for the emergence of new genetic forms. CASE PRESENTATION: VZV was detected in the CSF sample of an 11-year-old patient presenting with symptoms of encephalitis by real-time PCR diagnostics. To identify possible unknown aetiological pathogens, next-generation sequencing was performed, and revealed an HIV-1 co-infection. Alignments of concatenated HIV-1 genome fragments in the gag, pol, vif, env and nef regions and a near-complete VZV genome were analyzed by Bayesian inference, and phylogenetic trees were generated. The VZV sequence belongs to clade 5 and the HIV-1 sequence is a member of the CRF02_AG predominant circulating recombinant form in Ghana. CONCLUSIONS: Diagnostic tests for CSF HIV would be useful where possible in patients presenting with encephalitis due to VZV and other opportunistic viruses in Kumasi to shed light on the role of HIV in encephalitis cases in Ghana. This report reaffirms the role of the CRF02_AG circulating recombinant form in HIV infections in Ghana and also gives a preliminary genetic characterization of VZV in Kumasi, Ghana.
The Privileged Life of a Theoretical Observer
Creators: name: Gough, Douglas
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Memoirs

description: AbstractThis is a summary of my scientific career, biased by my personal view of events and unashamedly concentrating on those aspects of some of the scientific developments to which I have contributed. A selective unbiased alternative has been written by Christensen-Dalsgaard and Thompson (A selective overview. In: Thompson, M.J., Christensen-Dalsgaard, J. (Eds.) Stellar Astrophysical Fluid Dynamics, Cambridge University Press, pp. 1 – 19, 2003), followed by some further remarks by Christensen-Dalsgaard (Unsolved Problems in Stellar Physics: A Conference in Honour of Douglas Gough, American Institute of Physics Conference Series, 948, xii, 2007).
A systematic analysis of splicing variants identifies new diagnoses in the 100,000 Genomes Project.
Creators: name: Blakes, Alexander JM
name: Wai, Htoo A
name: Davies, Ian
name: Moledina, Hassan E
name: Ruiz, April
name: Thomas, Tessy
name: Bunyan, David
name: Thomas, N Simon
name: Burren, Christine P
name: Greenhalgh, Lynn
name: Lees, Melissa
name: Pichini, Amanda
name: Smithson, Sarah F
name: Taylor Tavares, Ana Lisa
name: O'Donovan, Peter
name: Douglas, Andrew GL
name: Genomics England Research Consortium, Splicing
name: Whiffin, Nicola
name: Baralle, Diana
name: Lord, Jenny
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research

description: Funder: Wessex Medical Research; doi: http://dx.doi.org/10.13039/501100008176
description: Funder: Rosetrees Trust; doi: http://dx.doi.org/10.13039/501100000833
description: Funder: Health Education England
description: BACKGROUND: Genomic variants which disrupt splicing are a major cause of rare genetic diseases. However, variants which lie outside of the canonical splice sites are difficult to interpret clinically. Improving the clinical interpretation of non-canonical splicing variants offers a major opportunity to uplift diagnostic yields from whole genome sequencing data. METHODS: Here, we examine the landscape of splicing variants in whole-genome sequencing data from 38,688 individuals in the 100,000 Genomes Project and assess the contribution of non-canonical splicing variants to rare genetic diseases. We use a variant-level constraint metric (the mutability-adjusted proportion of singletons) to identify constrained functional variant classes near exon-intron junctions and at putative splicing branchpoints. To identify new diagnoses for individuals with unsolved rare diseases in the 100,000 Genomes Project, we identified individuals with de novo single-nucleotide variants near exon-intron boundaries and at putative splicing branchpoints in known disease genes. We identified candidate diagnostic variants through manual phenotype matching and confirmed new molecular diagnoses through clinical variant interpretation and functional RNA studies. RESULTS: We show that near-splice positions and splicing branchpoints are highly constrained by purifying selection and harbour potentially damaging non-coding variants which are amenable to systematic analysis in sequencing data. From 258 de novo splicing variants in known rare disease genes, we identify 35 new likely diagnoses in probands with an unsolved rare disease. To date, we have confirmed a new diagnosis for six individuals, including four in whom RNA studies were performed. CONCLUSIONS: Overall, we demonstrate the clinical value of examining non-canonical splicing variants in individuals with unsolved rare diseases.
“PErCEIVE in Umbria”: Evaluation of anti-influenza vaccination's perception among Umbrian Pharmacists
Creators: name: Gianfredi, Vincenza
name: Nucci, Daniele
name: Salvatori, Tania
name: Orlacchio, Filiberto
name: Villarini, Milena
name: Moretti, Massimo
Publisher: name: Department of Health Science - University of Genoa
Year: 2018
Subjects: Anti-flu vaccine, Pharmacist, Vaccine Knowledge, Vaccine attitude, Italy, cross sectional study

description: Vaccines recommendations are available for both healthcare professionals and the general public, but although the vaccination is the most effective method to prevent infectious diseases, the coverage is still behind the recommended rate.  In Italy, according to a recent study, the anti-flu vaccination rate among healthcare worker range between 9% to 30%. The aim of our study was to identify knowledge, attitude and behaviours regarding influenza vaccination among community pharmacists in order to increase the coverage rate among healthcare professional. “PErCEIVE (Pharmacist pERCEption on Influenza VaccinE) in Umbria” was a cross sectional survey among community pharmacists in Umbria conducted between 16th November 2015 to 29th February 2016. The questionnaire was anonymous, on-line self-administered survey.Statistical analysis were performed using STATA/SE 12 software. The response rate was 28.91% (n= 72/249). Among the studied population 76.39% (n=55) had never performed influenza vaccine during the previous 5 years. Regarding source of information, only 15.28% of the subjects (n=11) consulted the scientific publications, vs 52.78% (n=38) who did not show any kind of interest upon the influenza vaccine. Our results show a low attitude to be vaccinated among pharmacists together with a low grade of awareness regarding the important role that pharmacists might play in order to reduce influenza burden, to promote health literacy among their patients and to decrease the risk of patients infection. Pharmacists might be crucial healthcare workers involved in health promotion, in vaccines’ uptake and practices progression.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
ENERGY DRINK AND GINSENG CONSUMPTION BY ITALIAN UNIVERSITY STUDENTS: A CROSS-SECTIONAL STUDY
Creators: name: Majori, Silvia
name: Pilati, Sobha
name: Gazzani, Diana
name: Paiano, Jacopo
name: Ferrari, Sara
name: Sannino, Anna
name: Checchin, Enrico
Publisher: name: Department of Health Science - University of Genoa
Year: 2018
Subjects: energy drink; ginseng; behavior; university students; Italy

description: Introduction. The consumption of energy drinks (ED) and ginseng by young people to enhance their mental and physical performance has become widespread. Reported side-effects of ED have raised doubts regarding their safety. This cross-sectional study investigates the phenomenon.

Methods. An anonymous questionnaire was administered to a representative sample of Italian university students. The resulting data were analyzed with Excel 2013, STATA 13 and GraphPad INSTAT software.

Results. ED and ginseng consumption was reported by 38.6% and 37.4% of the students, respectively. More than 70% of ED and ginseng users were 18 to 22 years old. Excluding non-responders, ED consumers were mostly males (51.8% vs. 33.0%), contrary to ginseng consumers (females 40.4% vs. 30.9%). The most frequently reported academic and other reasons for ED use were: “to study longer” (47.5%), and “to socialize” (29.1%). The most often used combinations were ED containing alcohol (65.6%) and ginseng-coffee beverages (71.8%).
Conclusions. The diffusion of ED and ginseng consumption warrants prevention and monitoring measures, and deserves further analysis.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
Determination of total extractable organofluorine (EOF) in food contact materials and target and non-target analysis of per- and polyfluoroalkyl substances using LC–MS/MS and LC–HRMS simultaneously coupled to ICP-MS
Creators: name: Nxumalo, Tengetile
name: Akhdhar, Abdullah
name: Müller, Viktoria
name: Al Zbedy, Amnah
name: Raab, Andrea
name: Jovanovic, Milica
name: Leitner, Erich
name: Kindness, Andrew
name: Feldmann, Jörg
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health

description: Food contact materials (FCMs) from three countries were analysed for all extractable organofluorines (EOFs) from the materials and subsequently by target and non-target analysis for per- and polyfluoroalkyl substances (PFAS). The EOF varied by two orders of magnitude for FCM from UK and Saudi Arabia ranging between 2.14 and 483 ng cm−2 (0.2–48 ng g−1) showing that one quarter of all samples were above the Danish regulation for PFAS in FCM. Target PFAS showed high variability in composition and accounted for less than 1% of the EOF. Non-target PFAS screening using HPLC–ICP-MS and coupled simultaneously to HRMS showed the occurrence of organofluorines which were identified by neither LC–MS/MS nor LC–HRMS. This illustrates that the current target PFAS approaches fail to identify EOFs from FCM, which would be a problem with the new EU proposal to ban all PFAS.
MEASLES OUTBREAK FROM FEBRUARY TO AUGUST 2017 IN MESSINA, ITALY
Creators: name: Palamara, Maria Angela
name: Visalli, Giuseppa
name: Picerno, Isa
name: Marano, Fernanda
name: D'Andrea, Giuseppa
name: Facciolà, Alessio
Publisher: name: Department of Health Science - University of Genoa
Year: 2018
Subjects: measles; outbreak; vaccination coverage

description: Abstract

Introduction. Measles continues to be a major public health issue worldwide, with high morbidity and mortality rates. The disease remains endemic in 14 European countries, including Italy where, from 2013 to 2016, over 5,000 cases have been reported. In 2017, many Italian regions, including Sicily, have reported many cases of measles. In this study, we described the latest measles outbreak in the city of Messina, from 1st February to 31st August 2017.

Methods. We considered all reported measles cases that came to the “Public Health, Epidemiology and Preventive Medicine” Operative Unit of the Messina Provincial Health Agency Prevention Department, which receives all reported cases of measles in the Messina province.

Results. From 1st February to 31st August 2017, a total of 59 measles cases were reported, of which 44 were confirmed, nine were classified as possible, four were probable and two cases were discarded. Of the 57 possible, probable and confirmed cases, 31 (54%) were males and 26 (46%) were females. Moreover, 54 (95%) had not been previously vaccinated while the remaining cases had documented evidence of one (two cases) or two doses (one case). Genotype B3 was identified in 39 cases (68%) by the regional reference laboratory in Palermo.

Conclusion. Despite the development of an effective vaccination, unfortunately measles continues to threaten the lives of millions of children worldwide each year. The suboptimal immunisation level in Italy has led to an increase in the transmission of measles with detrimental effects on both public health and ongoing measles elimination efforts.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
IMPACT OF ERYTHROCYTE SPECIES ON ASSAYS FOR INFLUENZA SEROLOGY
Creators: name: Trombetta, Claudia Maria
Publisher: name: Department of Health Science - University of Genoa
Year: 2018

description: The influenza viruses have the ability to agglutinate erythrocytes by binding to sialic acid receptors on the host cell. Human influenza viruses preferentially bind to sialic acid linked to galactose by α 2,6 linkage, while avian influenza viruses preferentially bind to sialic acid linked to Gal by 2,3 linkage. There is a close correlation between the ability of influenza A viruses to agglutinate erythrocytes from different animal species and their receptor specificity. The haemagglutination and haemagglutination inhibition assays are influenced by the species of erythrocytes. To provide an overview of the expression of sialic acid receptors on different erythrocytes, avian (turkey, chicken, pigeon) and mammalian (sheep, horse, human) species have been analysed. The erythrocytes from the same avian and mammalian species have been evaluated by haemagglutination and haemagglutination inhibition assays with seasonal and avian strains. Chicken, turkey and human erythrocytes display both types of linkages. Horse and sheep erythrocytes show almost exclusively a sialic acid α 2,3 Gal linkage, while pigeon erythrocytes express almost exclusively a sialic acid α 2,6 Gal linkage. Chicken and turkey erythrocytes seem to be the most appropriate for both assays with seasonal influenza strains, in addition to pigeon erythrocytes, particularly for the B strains. In the case of the avian strain, chicken erythrocytes are suitable for haemagglutination assay and horse erythrocytes for haemagglutination inhibition assay. The choice of erythrocytes has a significant impact on the titres measured by both assays.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
Cirsium tuberosum All.
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Cirsium
Cirsium tuberosum

description: Cirsium tuberosum (L.) All.
Artbeschreibung: Ähnlich wie C. rivulare, aber Wurzeln spindelförmig verdickt (nur bei dieser C. -Art), Blattabschnitte meist 2- bis mehrteilig oder grob gezähnt, unterseits dünn spinnwebig-filzig, Köpfe einzeln auf langen Stielen, Früchte 3-4 mm lang.
Blütezeit: 6-8
Standort und Verbreitung in der Schweiz: Wechselfeuchte Magerwiesen, Sümpfe / kollin-montan / J, vereinzelt M (ZH u.a.)
Verbreitung global: Mitteleuropäisch
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl Ffeucht; Feuchtigkeit mässig wechselnd (± 1-2 Stufen)Lichtzahl LhalbschattigSalzzeichen--Reaktionszahl Rneutral bis basisch (pH 5.5-8.5)Temperaturzahl Tunter-montan und ober-kollinNährstoffzahl NnährstoffarmKontinentalitätszahl Ksubozeanisch bis subkontinental (mittlere Luftfeuchtigkeit, mässige Temperaturschwankungen und mässig tiefe Wintertemperaturen)
Volksname Deutscher Name: Knollige Kratzdistel Nom français: Cirse tubéreux Nome italiano: Cardo tuberoso
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116
Probabilistic risk assessment of dietary exposure to lead in residents of Guangzhou, China
Creators: name: Song, Shaofang
name: Liu, Yufei
name: Zhang, Weiwei
name: Li, Yan
name: Zhang, Yuhua
name: Wang, Yanyan
name: Zeng, Jinheng
name: Pan, Xinhong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Lead and its compounds can have cumulative harmful effects on the nervous, cardiovascular, and other systems, and especially affect the brain development of children. We collected 4918 samples from 15 food categories in 11 districts of Guangzhou, China, from 2017 to 2022, to investigate the extent of lead contamination in commercial foods and assess the health risk from dietary lead intake of the residents. Lead was measured in the samples using inductively coupled plasma mass spectrometry. Dietary exposure to lead was calculated based on the food consumption survey of Guangzhou residents in 2011, and the health risk of the population was evaluated using the margin of exposure (MOE) method. Lead was detected in 76.5% of the overall samples, with an average lead content of 29.4 µg kg−1. The highest lead level was found in bivalves. The mean daily dietary lead intakes were as follows: 0.44, 0.34, 0.25, and 0.28 µg kg−1 body weight (bw) day−1 for groups aged 3–6, 7–17, 18–59, and ≥ 60 years, respectively. Rice and rice products, leafy vegetables, and wheat flour and wheat products were identified as the primary sources of dietary lead exposure, accounting for 73.1%. The MOE values demonstrated the following tendency: younger age groups had lower MOEs, and 95% confidence ranges for the groups aged 3–6 and 7–17 began at 0.6 and 0.7, respectively, indicating the potential health risk of children, while those for other age groups were all above 1.0. Continued efforts are needed to reduce dietary lead exposure in Guangzhou.
Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships.
Creators: name: De Vlaming, Ronald
name: Slob, Eric AW
name: Groenen, Patrick JF
name: Rietveld, Cornelius A
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Software
SNP heritability
Genetic correlation
GREML
Genetic factor model
Genomic SEM

description: Funder: NIHR Cambridge BRC
description: BACKGROUND: Heritability and genetic correlation can be estimated from genome-wide single-nucleotide polymorphism (SNP) data using various methods. We recently developed multivariate genomic-relatedness-based restricted maximum likelihood (MGREML) for statistically and computationally efficient estimation of SNP-based heritability ([Formula: see text]) and genetic correlation ([Formula: see text]) across many traits in large datasets. Here, we extend MGREML by allowing it to fit and perform tests on user-specified factor models, while preserving the low computational complexity. RESULTS: Using simulations, we show that MGREML yields consistent estimates and valid inferences for such factor models at low computational cost (e.g., for data on 50 traits and 20,000 individuals, a saturated model involving 50 [Formula: see text]'s, 1225 [Formula: see text]'s, and 50 fixed effects is estimated and compared to a restricted model in less than one hour on a single notebook with two 2.7 GHz cores and 16 GB of RAM). Using repeated measures of height and body mass index from the US Health and Retirement Study, we illustrate the ability of MGREML to estimate a factor model and test whether it fits the data better than a nested model. The MGREML tool, the simulation code, and an extensive tutorial are freely available at https://github.com/devlaming/mgreml/ . CONCLUSION: MGREML can now be used to estimate multivariate factor structures and perform inferences on such factor models at low computational cost. This new feature enables simple structural equation modeling using MGREML, allowing researchers to specify, estimate, and compare genetic factor models of their choosing using SNP data.
EMD-based data augmentation method applied to handwriting data for the diagnosis of Essential Tremor using LSTM networks.
Creators: name: Otero, José Fernando Adrán
name: López-De-Ipina, Karmele
name: Caballer, Oscar Solans
name: Marti-Puig, Pere
name: Sánchez-Méndez, José Ignacio
name: Iradi, Jon
name: Bergareche, Alberto
name: Solé-Casals, Jordi
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/639/166/985
/692/699/375/346
article

description: The increasing capacity of today's technology represents great advances in diagnosing diseases using standard procedures supported by computer science. Deep learning techniques are able to extract the characteristics of temporal signals to study their patterns and diagnose diseases such as essential tremor. However, these techniques require a large amount of data to train the neural network and achieve good results, and the more data the network has, the more accurate the final model implemented. In this work we propose the use of a data augmentation technique to improve the accuracy of a Long short-term memory system in the diagnosis of essential tremor. For this purpose, the multivariate Empirical Mode Decomposition method will be used to decompose the original temporal signals collected from control subjects and patients with essential tremor. The time series obtained from the decomposition, covering different frequency ranges, will be randomly shuffled and combined to generate new artificial samples for each group. Then, both the generated artificial samples and part of the real samples will be used to train the LSTM network, and the remaining original samples will be used to test the model. The experimental results demonstrate the capability of the proposed method, which is compared to a set of 10 different data augmentation methods, and in all cases outperforms all other methods. In the best case, the proposed method increases the accuracy of the classifier from 83.20% to almost 93% when artificial samples are generated, which is a promising result when only small databases are available.
Detection of milk adulteration using coffee ring effect and convolutional neural network
Creators: name: Parsain, Tapan
name: Tripathi, Ajay
name: Tiwari, Archana
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: A low-cost and effective method is reported to identify water and synthetic milk adulteration of cow’s milk using coffee ring patterns. The cow’s milk samples were diluted with tap water (TW), distilled water (DW) and mineral water (MW) and drop cast onto glass slides to observe coffee ring patterns. The area of the ring, total particle area and average particle diameter were extracted from these patterns. For each ring, the ratio of total particle area versus total ring area was calculated. The area ratio, regardless of water adulterants, follows an exponential model with respect to average particle diameter. Unlike TW, the ratio for DW and MW adulterated milk are clustered and classified together with respect to the particle diameter. These results were independent of dilution level and are used for adulterant classification. The ring of milk adulterated using synthetic milk gave multiple concentric rings, flower-like structures, and oil globules throughout the dilution level. An Alexnet model was used to classify water and synthetic milk adulterants in authentic milk. The trained model could achieve 96.7% and 95.8% accuracy for binary and tertiary classification respectively. These results enable us to distinguish synthetic milk from pure milk and segregate DW and MW with respect to TW adulterated milk.
Cirsium vulgare
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Cirsium
Cirsium vulgare

description: Cirsium vulgare (Savi) Ten.
Artbeschreibung: 50-150 (-200) cm hoch. Stängel spinnwebig, durch herablaufende Blattränder stachelig geflügelt. Blätter steif, fiederteilig, mit lanzettlichen, in einen kräftigen, gelblichen Stachel endigenden Abschnitten, oberseits stachelig behaart, grün, unterseits weissfilzig. Blüten purpurn. Köpfe einzeln. Hülle der blühenden Köpfe 3-5 cm lang, zerstreut spinnwebig, Hüllblätter mit kräftigem Stachel. Früchte 3-4 mm, Pappus 2-3 cm lang.
Blütezeit: 7-9
Standort und Verbreitung in der Schweiz: Wegränder, Ödland, Schuttplätze / kollin-montan(-subalpin) / CH
Verbreitung global: Eurasiatisch
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl Fmässig feucht; Feuchtigkeit mässig wechselnd (± 1-2 Stufen)Lichtzahl LhellSalzzeichen1Reaktionszahl Rneutral bis basisch (pH 5.5-8.5)Temperaturzahl Tunter-montan und ober-kollinNährstoffzahl NnährstoffreichKontinentalitätszahl Ksubozeanisch bis subkontinental (mittlere Luftfeuchtigkeit, mässige Temperaturschwankungen und mässig tiefe Wintertemperaturen)
Volksname Deutscher Name: Gemeine Kratzdistel, Lanzettblättrige Kratzdistel Nom français: Cirse commun Nome italiano: Cardo asinino
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116
Information sur les instruments de cobla : les anches de prime (tible)
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2022

Abstract
ЖИНОЯТ ПРОЦЕССИСИДА ЛАВОЗИМДАН ЧЕТЛАШТИРИШ ПРОЦЕССУАЛ МАЖБУРЛОВ ЧОРАСИНИ АМАЛГА ОШИРИШ ТАРТИБИ ВА ҲОЗИРГИ КУНДАГИ МУАММОЛАР.
Creators: name: Хамидов, А.А.
Publisher: name: Zenodo
Year: 2024

description: Жиноят ва бошқа ҳуқуқбузарликларнинг олдини олиш, жиноят содир этиш, унга суиқасд қилиш ёки содир этишга тайёргарлик кўрилаётгани тўғрисидаги ариза ва хабарларни текшириш ҳамда тегишлича жиноятни аниқлаш, унда айбли шахсларни фош этиш ва айб учун жавобгарлик муқаррарлигини таьминлаш демократик-ҳуқуқий давлат органларининг муҳим вазифаларидан биридир.
Conyza bonariensis Cronquist
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Conyza
Conyza bonariensis

description: Conyza bonariensis (L.) Cronquist
Artbeschreibung: 20-60 cm hoch, dicht anliegend und abstehend behaart. Blätter graugrün, gelegentlich gewellt, lineal-lanzettlich, einnervig, obere lineal. Zentrale Blütenrispe verkürzt, von den langen Seitenästen teilweise überragt. Hülle rauhaarig, 3-5 mm breit (zur Fruchtreife bis 10 mm), 4-6 mm lang. Hüllblätter an der Spitze oft rot. Randblüten mit 3-4 Zähnchen, meist ohne Zunge.
Blütezeit: 7-10
Standort und Verbreitung in der Schweiz: Ruderalstellen, Felder, Brachen / kollin / CH
Verbreitung global: Stammt aus Südamerika
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl FfrischLichtzahl LhellSalzzeichen--Reaktionszahl Rschwach sauer bis neutral (pH 4.5-7.5)Temperaturzahl Tsehr warm-kollin (nur an wärmsten Stellen, Hauptverbreitung in Südeuropa)Nährstoffzahl NnährstoffreichKontinentalitätszahl Ksubozeanisch (hohe Luftfeuchtigkeit, geringe Temperaturschwankungen, eher milde Winter)
Volksname Deutscher Name: Südamerikanisches Berufkraut Nom français: Vergerette de Buenos Aires, Conyze de Buenos Aires Nome italiano: Saeppola di Buenos Aires
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116
BETA values from DNA methylation (selected differential regions)
Creators: name: Herrero-Roldán, Silvia
name: León, Inmaculada
name: Rodrigo, María José
name: López Rodríguez, Maykel
name: Mitchell, Colter
name: Fisher, Jonah
name: Lage-Castellanos, Agustín
Publisher: name: Zenodo
Year: 2022
Subjects: epigenetics
Parental neglect
DNA methylation
behavioral epigenetics

description: Studies of DNA methylation have revealed the biological mechanisms by which life adversity confers risk for later physical and mental health problems. What remains unknown is the "biologically embedding" of maternal adverse experiences resulting in maladaptive parenting and whether these epigenetic effects are transmitted to the next generation. This study focuses on neglectful mothering indexed by a severe disregard for the basic and psychological needs of the child. Using the Illumina Human Methylation 850K BeadChip in saliva samples, we identified genes with differentially methylated regions (DMRs) in those mothers with, versus those without, neglectful behavior (n = 51 vs 87) that present similar DMRs patterns in their children being neglected versus non-neglected (n = 40 vs 75). Mothers reported the emotional intensity of adverse life events. After covariate adjustment and multiple testing corrections, we identified 69 DMRs in the mother epigenome and 42 DMRs in the child epigenome that were simultaneously above the α = 0.01 threshold. The common set of nine DMRs contained genes related to childhood adversity, neonatal and infant diabetes, child neurobehavioral development, and other health problems such as obesity, hypertension, cancer, posttraumatic stress, and Alzheimer's disease; four of the genes were associated with maternal life adversity. Identifying a shared epigenetic signature of neglect linked to maternal life adversity is an essential step in breaking the intergenerational transmission of one of the most common forms of childhood maltreatment.
description: RFunding provided by: Spanish Ministry of Economy and Competitiveness and the European Regional Development Fund**
Crossref Funder Registry ID:
Award Number: RTI2018-098149-B-100
description: This dataset show Beta values from methylation sequencing from saliva samples. Only the beta samples of the regions analyzed in the paper are shown. The data is a collection of .rds files containing the Beta values. For each row of Table 2 of the main text (referred to as the different genes), we extracted the Beta values for the differential methylated CpGs between the two groups of mothers. Those CpGs correspond within the genomic positions defined in that table by the column Genomic coordinates (Start and End). The data was separated by files corresponding to the mothers for each gene and children per each gene. Two files provide the label for each mother according to her group of belonging (control or neglectful) (GroupMothers.rds and GroupChildren.rds).
EFFECTS OF ANTICOAGULATION THERAPY WITH VITAMIN K ANTAGONISTS ON HOSPITALIZATIONS AND EMERGENCY ROOM ACCESSES IN GROSSETO (ITALY)
Creators: name: Troiano, Gianmarco
Publisher: name: Department of Health Science - University of Genoa
Year: 2018

description: Background A lot of drug groups are associated with preventable drug-related admissions. Coumarin derivatives, prescribed for the treatment and prevention of deep vein thrombosis or pulmonary embolism or prevention of systemic embolism or stroke in patients with prosthetic heart valves or atrial fibrillation, are often associated  with bleeding. The aim of our study was to estimate the impact of the anticoagulant therapy in the elderly population (over 65 years old) living in Grosseto province, through the hospitalizations and the visits to emergency room, using only current data flows.

Methods In 2013 we conducted a cross sectional study analyzing the database of all pharmaceutical prescriptions, selecting patients living in Grosseto (Italy), which received at least two prescriptions of coumarin derivatives in 2012.  We analyzed the admissions to hospital and the accesses to the emergency rooms (ER) made by each patient, focusing especially on those related to bleeding. For each access to ER we recorded the date, time of stay, diagnosis and outcome. For each hospitalization the information we recorded were the date of admission and discharge diagnosis.

Results 3684 patients were included in our study. 261 (7.1%) patients visited the emergency room for bleeding; 37 (1%) for intracranial bleeding. The accesses made by men were higher than those made by women. The average time of stay in ER was 349 minutes. The admissions to hospital were 96 (2.6%); 42 (1.1%) were admitted to hospital with a diagnosis of major vascular event. 53 patients (20.3 %), accessed to the ER more than one time. The 11.5% was admitted to the hospital more than one time.

Conclusions Our study tried to estimate the impact of the anticoagulant therapy in the elderly population, living in Grosseto province, showing an important impact of this therapy on the accesses at ER and on admissions at hospital.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
Conyza canadensis Cronquist
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Conyza
Conyza canadensis

description: Conyza canadensis (L.) Cronquist
Artbeschreibung: 20-80(-120) cm hoch, +/- rauhaarig. Blätter lanzettlich, ganzrandig oder gezähnt. Gesamtblütenstand schmal zylindrisch. Hülle 3-4 mm lang und 2-3 mm breit (zur Fruchtreife bis 5 mm), kahl oder spärlich behaart. Blüten gelblich-weiss. Randblüten mit ca. 1 mm langer Zunge. Früchte 1-1,5 mm, mit 3 mm langem Pappus.
Blütezeit: 7-9
Standort und Verbreitung in der Schweiz: Wegränder, Schuttplätze, Waldschläge / kollin-montan(-subalpin) / CH
Verbreitung global: Ursprünglich nordamerikanisch
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl FfrischLichtzahl LhellSalzzeichen--Reaktionszahl Rneutral bis basisch (pH 5.5-8.5)Temperaturzahl Tkollin (Laubmischwälder mit Eichen)Nährstoffzahl Nmässig nährstoffarm bis mässig nährstoffreichKontinentalitätszahl Ksubozeanisch bis subkontinental (mittlere Luftfeuchtigkeit, mässige Temperaturschwankungen und mässig tiefe Wintertemperaturen)
Volksname Deutscher Name: Kanadisches Berufkraut Nom français: Vergerette du Canada Nome italiano: Saeppola canadese
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116
ENERGY DRINK CONSUMPTION: A SURVEY IN HIGH SCHOOL STUDENTS AND ASSOCIATED PSYCHOLOGICAL EFFECTS
Creators: name: Scuri, Stefania
name: Petrelli, Fabio
name: Tesauro, Marina
name: Carrozzo, Federica
name: Kracmarova, Lenka
name: Grappasonni, Iolanda
Publisher: name: Department of Health Science - University of Genoa
Year: 2018
Subjects: energy drinks, abuse, caffeine, alcohol, young

description: Introduction

Energy drinks represent an emerging health problem among young people. “Energy drinks” generally refer to a class of beverages containing sugars and various combinations of bioactive ingredients such as caffeine, taurine etc. Also the mix of energy drinks with alcohol is fairly frequent among young people and could be associated with dangerous effects.

Methods

In 2016-2017, a cross-sectional study was conducted in 1581 students attending eight high school in the Marche Region. Data were collected via an anonymous self-administered questionnaire.

Results
The 27.7% of students use energy drinks  and the majority, corresponding with the 93.0%,  are aware of the main ingredients contained in energy drinks. The main activities for which young people use these drinks are: sport, leisure, pleasure, study. Young people who admit to using alcohol mixed with energy drinks more than 4 times a month are an alarming fact.

Conclusions
This research confirms that energy drinks are used more by young males and especially by those who practice sports. Furthermore, the use these beverages to increase the concentration in the study and to be more brilliant in free time, is confirmed.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
Mental and physical effects of energy drinks consumption in an Italian young people group: a pilot study
Creators: name: Petrelli, Fabio
name: Grappasonni, Iolanda
name: Evangelista, Daria
name: Pompei, Pierluigi
name: Broglia, Gianluca
name: Cioffi, Pasquale
name: Kracmarova, Lenka
name: Scuri, Stefania
Publisher: name: Department of Health Science - University of Genoa
Year: 2018
Subjects: energy drinks, young, physical stress, mental stress

description: Introduction

The primary consumers of energy drinks were athletes, to combat fatigue, but in reality,  thanks to their fast expansion and economic growth,  young adults and teenagers represent the new target market. Consumption of energy drinks by both recreational and competitive athletes has increased dramatically in recent years, though they are often unaware of what is being ingested, believing to improve their physical and psychological performance. The literature shows contradictions about the capacity of energy drinks to enhance psychophysical results.

In relation to probable adverse effects induced by the irregular consumption of energy drinks, which in several cases are not so clear, we decided to investigate the possible relationship between the intake of energy drinks and the presence of mental and physical stress in young people and athletes.

Methods

Two experimental sessions, separated at least by 1 week, according to a randomized cross-over design, following this protocol were conducted: in the first session a mental and physical stress was conducted without the consumption of energy drinks, the second after energy drinks consumption. BAI (Beck Anxiety Inventory) and BDI (Beck Depression Inventory II) test have been used to test the mental stress, and a “cycle ergometer test” to test the physical stress.

Results

 BAI and BDI tests results showed that before the consumption of energy drinks, subjects are considered in the range of “minimal level of anxiety”, (10 and 60 percentiles) and do not report a level of depression. After the energy drinks consumption, a  “mild level of anxiety” has been recorded, and the BDI showed a case with a pathological profile. The physical test recorded a small increase in the maximum heart rate was verified with the intake of an energetic beverage.

 Conclusions

 The stimulating effect of  EDs on nervous system and cardiovascular system, must be checked and studied in deeper detail, because it may represent a risk for the health of young athletes.
description: Journal of Preventive Medicine and Hygiene, Vol 59, No 1 (2018): 2018591
Conyza sumatrensis E. Walker
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Conyza
Conyza sumatrensis

description: Conyza sumatrensis (Retz.) E. Walker
Artbeschreibung: Wie C. bonariensis, aber 50-200 cm hoch, Gesamtblütenstand zylindrisch bis pyramidenförmig, Spitze nicht von den Seitenästen überragt. Blätter breit-lanzettlich, mit zahlreichen Nerven. Hüllblätter an der Spitze bleich. Randblüten nur mit 1-2 Zähnchen an der Spitze.
Blütezeit: 7-10
Standort und Verbreitung in der Schweiz: Ruderalstellen, Felder, Brachen / kollin / CH, in Ausbreitung
Verbreitung global: Stammt aus Südamerika (?)
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl Fmässig trockenLichtzahl LhellSalzzeichen1Reaktionszahl Rneutral bis basisch (pH 5.5-8.5)Temperaturzahl Tsehr warm-kollin (nur an wärmsten Stellen, Hauptverbreitung in Südeuropa)Nährstoffzahl NnährstoffreichKontinentalitätszahl Ksubozeanisch bis subkontinental (mittlere Luftfeuchtigkeit, mässige Temperaturschwankungen und mässig tiefe Wintertemperaturen)
Volksname Deutscher Name: Sumatra-Berufkraut Nom français: Vergerette de Sumatra, Conyze de Sumatra Nome italiano: Saeppola di Sumatra
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116
Coreopsis lanceolata L.
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Coreopsis
Coreopsis lanceolata

description: Coreopsis lanceolata L.
Artbeschreibung: 50-100 cm hoch. Blätter lanzettlich, fein marmoriert, ganzrandig, bis 8 cm lang. Köpfe endständig, Durchmesser ca. 5 cm. Alle Blüten leuchtend gelb, Zungenblüten am Grund braunrot, ca. 1 cm breit, vorn grob gezähnt.
Blütezeit: 6-9
Standort und Verbreitung in der Schweiz: Gelegenlich aus Gärten verwildert /
Verbreitung global: Stammt aus Nordamerika
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl FfrischLichtzahl LhellSalzzeichen--Reaktionszahl Rschwach sauer bis neutral (pH 4.5-7.5)Temperaturzahl Twarm-kollinNährstoffzahl Nmässig nährstoffarm bis mässig nährstoffreichKontinentalitätszahl Ksubozeanisch bis subkontinental (mittlere Luftfeuchtigkeit, mässige Temperaturschwankungen und mässig tiefe Wintertemperaturen)
Volksname Deutscher Name: Mädchenauge, Jungferngesichtchen, Wanzenblume Nom français: Coréopsis lancéolé Nome italiano: Coreopsis lanceolata
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116
Anthemis cotula
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Anthemis
Anthemis cotula

description: Cotula australis (Spreng.) Hook. f.
Artbeschreibung: Stängel niederliegend bis aufsteigend, 1-15 cm lang, behaart. Blätter 1-2fach fiederschnittig, 5-20 mm lang. Köpfchen ohne Zungenblüten, 2-7 mm breit, auf 1-5 cm langen Stielen. Blütenboden ohne Spreublätter. Innere Blüten 2geschlechtig, gelb-weisslich bis grünlich, die weiblichen (äusseren) ohne Krone. Früchte ohne Pappus, ca. 1 mm lang, die äusseren gestielt und geflügelt.
Blütezeit: 1-6(-12)
Standort und Verbreitung in der Schweiz: Sandige, nährstoffreiche Orte, Trittfluren, Strassenpflaster / kollin / TI
Verbreitung global: Stammt aus Australien
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl F--Lichtzahl L--Salzzeichen--Reaktionszahl R--Temperaturzahl T--Nährstoffzahl N--Kontinentalitätszahl K--
Volksname Deutscher Name: Australische Laugenblume Nom français: Cotule austral Nome italiano: Margherita australiana
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116
Crepis alpestris Tausch
Creators: name: Konrad Lauber
name: Gerhart Wagner
name: Andreas Gygax
Publisher: name: Haupt Verlag
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Crepis
Crepis alpestris

description: Crepis alpestris (Jacq.) Tausch
Artbeschreibung: 10-30 cm hoch, meist einköpfig, selten 2-5 köpfig, oben hell und kraus behaart. Stängel unten entfernt 1-3 blättrig. Grundblätter lanzettlich, buchtig gezähnt bis fiederteilig, kurz behaart, verkahlend, obere meist ganzrandig, mit verschmälertem Grund sitzend und etwas umfassend. Hülle 12-16 mm lang, drüsig oder drüsenlos. Blüten gelb. Früchte 7-11 mm lang, allmählich verschmälert bis geschnäbelt, mit 5-8 mm langem, weissem Pappus.
Blütezeit: 6-8
Standort und Verbreitung in der Schweiz: Lockere Magerrasen, Felsschutt, auf Kalk / (montan-)subalpin(-alpin) / BO, ANZ, ANE, GR, SH, TI
Verbreitung global: Mittel- und südosteuropäisch
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl FfrischLichtzahl LhellSalzzeichen--Reaktionszahl Rbasisch (pH 6.5->8.5)Temperaturzahl Tsubalpin (Fichtenwälder ohne Buchen bis zur Obergrenze der Fichte)Nährstoffzahl NnährstoffarmKontinentalitätszahl Ksubkontinental (niedrige relative Luftfeuchtigkeit, grosse Temperaturschwankungen, eher kalte Winter)
Volksname Deutscher Name: Alpen-Pippau Nom français: Crépide alpestre Nome italiano: Radicchiella alpestre
description: Published as part of Konrad Lauber, Gerhart Wagner & Andreas Gygax, 2018, Flora Helvetica - Asteraceae, pp. 1074-1250 in Flora Helvetica, Bern :Haupt Verlag on page 1116