cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Bridging Microbial Functional Traits With Localized Process Rates at Soil Interfaces
Creators: name: Blagodatskaya, Evgenia
name: Tarkka, Mika
name: Knief, Claudia
name: Koller, Robert
name: Peth, Stephan
name: Schmidt, Volker
name: Spielvogel, Sandra
name: Uteau, Daniel
name: Weber, Matthias
name: Razavi, Bahar S.
Publisher: name: Lausanne : Frontiers Media
Year: 2021
Subjects: subject: (bio)-pores
subject: detritusphere
subject: mycorrhizosphere
subject: rhizosphere
subject: soil aggregates
subject: soil priming
subject: statistical analysis of process locations
subject: trophic interactions
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: In this review, we introduce microbially-mediated soil processes, players, their functional traits, and their links to processes at biogeochemical interfaces [e.g., rhizosphere, detritusphere, (bio)-pores, and aggregate surfaces]. A conceptual view emphasizes the central role of the rhizosphere in interactions with other biogeochemical interfaces, considering biotic and abiotic dynamic drivers. We discuss the applicability of three groups of traits based on microbial physiology, activity state, and genomic functional traits to reflect microbial growth in soil. The sensitivity and credibility of modern molecular approaches to estimate microbial-specific growth rates require further development. A link between functional traits determined by physiological (e.g., respiration, biomarkers) and genomic (e.g., genome size, number of ribosomal gene copies per genome, expression of catabolic versus biosynthetic genes) approaches is strongly affected by environmental conditions such as carbon, nutrient availability, and ecosystem type. Therefore, we address the role of soil physico-chemical conditions and trophic interactions as drivers of microbially-mediated soil processes at relevant scales for process localization. The strengths and weaknesses of current approaches (destructive, non-destructive, and predictive) for assessing process localization and the corresponding estimates of process rates are linked to the challenges for modeling microbially-mediated processes in heterogeneous soil microhabitats. Finally, we introduce a conceptual self-regulatory mechanism based on the flexible structure of active microbial communities. Microbial taxa best suited to each successional stage of substrate decomposition become dominant and alter the community structure. The rates of decomposition of organic compounds, therefore, are dependent on the functional traits of dominant taxa and microbial strategies, which are selected and driven by the local environment.
On a conjecture of Erdos and Simonovits: Even Cycles
Creators: name: Keevash, Peter
name: Sudakov, Benny
name: Verstraete, Jacques
Publisher: name: arXiv
Year: 2011
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Let $\mc{F}$ be a family of graphs. A graph is {\em $\mc{F}$-free} if it contains no copy of a graph in $\mc{F}$ as a subgraph. A cornerstone of extremal graph theory is the study of the {\em Turán number} $ex(n,\mc{F})$, the maximum number of edges in an $\mc{F}$-free graph on $n$ vertices. Define the {\em Zarankiewicz number} $z(n,\mc{F})$ to be the maximum number of edges in an $\mc{F}$-free {\em bipartite} graph on $n$ vertices. Let $C_k$ denote a cycle of length $k$, and let $\mc{C}_k$ denote the set of cycles $C_{\ell}$, where $3 \le \ell \leq k$ and $\ell$ and $k$ have the same parity. Erdős and Simonovits conjectured that for any family $\mc{F}$ consisting of bipartite graphs there exists an odd integer $k$ such that $ex(n,\mc{F} \cup \mc{C}_k) \sim z(n,\mc{F})$. They proved this when $\mc{F}={C_4}$ by showing that $ex(n,\{C_4,C_5\}) \sim z(n,C_4)$. In this paper, we extend this result by showing that if $\ell \in \{2,3,5\}$ and $k > 2\ell$ is odd, then ${ex(n,\mc{C}_{2\ell} \cup {C_k}) \sim z(n,\mc{C}_{2\ell})$. Furthermore, if $k > 2\ell + 2$ is odd, then for infinitely many $n$ we show that the extremal $\mc{C}_{2\ell} \cup \{C_k\}$-free graphs are bipartite incidence graphs of generalized polygons. We observe that this exact result does not hold for any odd $k < 2\ell$, and furthermore the asymptotic result does not hold when $(\ell,k)$ is $(3,3)$, $(5,3)$ or $(5,5)$. Our proofs make use of pseudorandomness properties of nearly extremal graphs that are of independent interest.
Microbial degradation of crude oil in Arctic soils
Creators: name: Gossen, Randall G.
Publisher: name: University of Calgary
Year: 1973
Subjects: subject: QR 53 G66 1973A Aina Microfiche
subject: Petroleum - Microbiology
subject: Soil micro-organisms
subject: Soils - Arctic regions
subject: Soil pollution

description: Bibliography: p. 158-165.
Comments Of The Fwf On The Evaluation Of The Start Programme And Wittgenstein Award
Creators: name: Austrian Science Fund (FWF)
Publisher: name: Zenodo
Year: 2016
Subjects: Science Policy
FWF
Evaluation

description: The START Programme and Wittgenstein Award were added to the FWF's funding portfolio in 1996. The START Programme is designed to enable highly promising young researchers from all disciplines to plan their research on a long-term basis and with sufficient financial security. By assuming responsibility for the establishment/expansion and management of a research group, the programme allows principal investigators to gain the qualifications necessary for leading positions in the science and research system. The Wittgenstein Award aims to ensure that top-notch researchers who have reached outstanding achievements in all disciplines are provided with a maximum of freedom and flexibility in carrying out their research work. The award therefore aims to enable an extraordinary increase in the recipients' research output.

Between 1996 and 2014, a total of 114 START projects with an overall funding volume of EUR 132.6 million were awarded. 16% of the projects were awarded to women. The approval rate in the START Programme is approximately 13% (based on 2002–2014 results), and the amount of grants awarded is up to EUR 1.2 million per project.

Between 1996 and 2014, the Wittgenstein Award was conferred upon 30 researchers (including 4 women), who received EUR 42.4 million in overall funding. During that period, a total of 278 researchers were nominated for the prize. The award carries an endowment of up to EUR 1.5 million. In anticipation of the 20th anniversary of these two programmes, the FWF commissioned a team from the Fraunhofer ISI (Karlsruhe, Germany) and the Austrian Institute for SME Research (Vienna, Austria) to conduct an evaluation of the START Programme and the Wittgenstein Award. The evaluation project was led by Susanne Bührer. The goal of the evaluation was to assess the effects of these programmes and to lay the groundwork for a decision on how to run them in the future.

The evaluation was based on a mixed-methods approach consisting of bibliometric analysis with a control group comparison,1 online surveys of various target groups, expert interviews, case studies, an analysis of programme and monitoring data, and a validation workshop with key stakeholders.

The evaluation team's assessment of the two programmes is highly positive, and the evaluators recommend that the two programmes be continued in their current forms:

	 "A continuation of the START Programme in its present form is recommended without any reservations."
	"The Wittgenstein Award seems tailor-made to its target group and has an added value to the scientific system in Austria.”
description: Evaluation of the START Programme and the Wittgenstein Award. Sarah Seus, Eva Heckl, Susanne Bührer; with the participation of Niclas Meyer, Sonia Conchi, Tobias Burst, Christina Schmedes and Barbara Sinnemann. Karlsruhe, 2016. DOI: 10.5281/zenodo.50610 is supplemented by this upload.
Improving cold-start recommendations using item-based stereotypes
Creators: name: AlRossais, Nourah
name: Kudenko, Daniel
name: Yuan, Tommy
Publisher: name: [Erscheinungsort nicht ermittelbar] : Proquest
Year: 2021
Subjects: subject: Cold start
subject: New item
subject: New user
subject: Recommender systems
subject: Stereotypes
subject: Dewey Decimal Classification::000 | Allgemeines, Wissenschaft::000 | Informatik, Wissen, Systeme::004 | Informatik

description: Recommender systems (RSs) have become key components driving the success of e-commerce and other platforms where revenue and customer satisfaction is dependent on the user’s ability to discover desirable items in large catalogues. As the number of users and items on a platform grows, the computational complexity and the sparsity problem constitute important challenges for any recommendation algorithm. In addition, the most widely studied filtering-based RSs, while effective in providing suggestions for established users and items, are known for their poor performance for the new user and new item (cold-start) problems. Stereotypical modelling of users and items is a promising approach to solving these problems. A stereotype represents an aggregation of the characteristics of the items or users which can be used to create general user or item classes. We propose a set of methodologies for the automatic generation of stereotypes to address the cold-start problem. The novelty of the proposed approach rests on the findings that stereotypes built independently of the user-to-item ratings improve both recommendation metrics and computational performance during cold-start phases. The resulting RS can be used with any machine learning algorithm as a solver, and the improved performance gains due to rate-agnostic stereotypes are orthogonal to the gains obtained using more sophisticated solvers. The paper describes how such item-based stereotypes can be evaluated via a series of statistical tests prior to being used for recommendation. The proposed approach improves recommendation quality under a variety of metrics and significantly reduces the dimension of the recommendation model.
Network on Chip: a New Approach of QoS Metric Modeling Based on Calculus Theory
Creators: name: Nasri, Salem
Publisher: name: arXiv
Year: 2011
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: A NoC is composed by IP cores (Intellectual Propriety) and switches connected among themselves by communication channels. End-to-End Delay (EED) communication is accomplished by the exchange of data among IP cores. Often, the structure of particular messages is not adequate for the communication purposes. This leads to the concept of packet switching. In the context of NoCs, packets are composed by header, payload, and trailer. Packets are divided into small pieces called Flits. It appears of importance, to meet the required performance in NoC hardware resources. It should be specified in an earlier step of the system design. The main attention should be given to the choice of some network parameters such as the physical buffer size in the node. The EED and packet loss are some of the critical QoS metrics. Some real-time and multimedia applications bound up these parameters and require specific hardware resources and particular management approaches in the NoC switch. A traffic contract (SLA, Service Level Agreement) specifies the ability of a network or protocol to give guaranteed performance, throughput or latency bounds based on mutually agreed measures, usually by prioritizing traffic. A defined Quality of Service (QoS) may be required for some types of network real time traffic or multimedia applications. The main goal of this paper is, using the Network on Chip modeling architecture, to define a QoS metric. We focus on the network delay bound and packet losses. This approach is based on the Network Calculus theory, a mathematical model to represent the data flows behavior between IPs interconnected over NoC. We propose an approach of QoS-metric based on QoS-parameter prioritization factors for multi applications-service using calculus model.
Editorial: Exploring and Engineering Plant Specialized Metabolism: Latest Advances and New Horizons
Creators: name: Franke, Jakob
name: Zhang, Yang
name: Dang, Thu-Thuy T.
Publisher: name: Lausanne : Frontiers Media
Year: 2021
Subjects: subject: genomics
subject: metabolic engineering
subject: plant biochemistry
subject: transcription factors
subject: transcriptomics
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: [no abstract available]
Microbial activity in aspen soil of the Kananaskis woodland area Alberta, Canada with particular reference to cellulose decomposition
Creators: name: Akhlaq, Shiekh Mohammad
Publisher: name: University of Calgary
Year: 1973
Subjects: subject: QR 111 A436 1973
subject: Soil micro-organisms
subject: Forest soils
subject: Soils - Alberta
subject: Cellulose
subject: Aspen

description: Bibliography: p. 216-230.
Evaluation of Streptococcus oralis adhesion and biofilm formation on laser-processed titanium
Creators: name: Doll, Katharina
name: Veiko, Vadim
name: Karlagina, Yulia
name: Odintsova, Galina
name: Heine, Nils
name: Egorova, Elena
name: Radaev, Maxim
name: Chichkov, Boris
name: Stiesch, Meike
Publisher: name: Berlin : De Gruyter
Year: 2021
Subjects: subject: anatase
subject: antibacterial surface
subject: biofilm
subject: laser processing
subject: Streptococcus oralis
subject: titanium
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: To prevent implant-associated infections, surface modifications need to be developed that prevent bacterial colonisation and biofilm formation. In the present study, titanium surfaces were processed by nanosecond-pulsed laser ablation to generate a variety of different structures (anatase, rutile, Osteon, as well as Osteon additionally coated with silver and clove nanoparticles). Analysis of adhesion and biofilm formation of the oral pioneer bacterium Streptococcus oralis could demonstrate antibacterial properties of anatase surfaces. For clinical translation, the effect should be enhanced by further adaption and combined with the osseointegrative Osteon structure
Satire in Doctor Faustus
Creators: name: Barnes, Gerald
Publisher: name: University of Calgary
Year: 1979
Subjects: subject: PR 2664 B36 1979 Microfiche
subject: Marlowe, Christopher, 1564-1593. Doctor Faustus
subject: Satire - History and criticism

description: Bibliography: p. 145-150.
description: The three divergent readings of Marlowe as revolutionary iconoclast, as Christian moralist, or as ambiguous ironist become most pronounced in response to Doctor Faustus. The thesis will explain such divergence of critical opinion by approaching the play as Marlowe 's formal attempt at dramatic satire, not tragedy. The influence of classical comedy on Jonson 's satiric drama has been recognised, but similar study has yet to be conducted into Marlowe 's knowledge and use of classical models. The first Chapter will assess Marlowe's contact with Roman comedy before offering an analysis of his typical mode of satire in the Plautine scenes of The Jew of Malta. The second Chapter will consider whether the satyr-drama of Greece could have influenced Marlowe's satiric conception of Doctor Faustus, and a formal comparison will be made between the two kinds of drama. Their connection is ultimately justified by the Renaissance theories of satire as the direct utterance of satyrs and by there being a demonstrable continuity b e twee n the satyr and the medieval devil. The classical ancestry of the devil creates an ambivalence in the play's spectacle, and it may be argued that the old Grecian deity is used to satirise the play's medieval eschatology. A more orthodox view may see the satyrdevils to bolster the Christian purpose of the play, which is moral rebuke by means of satire. This dialectical development necessitates a Chapter on the relationship of Doctor Faustus to medieval drama, in which special attention is given to the devil in order to appreciate Marlowe's original dramatisation of that theatrical figure. The use of the all-but-obsolete form of the early Morality is seen as a politic way for Marlowe to satirise certain facets of Christian belief, and the drama of Euripides is forwarded as a classical model that helps us understand how the play may be both orthodox and unorthodox. The final Chapter does not seek to identify Faustus with his creator in the Romantic manner; instead it sees him as the primary target of the play's satire. A satiric interpretation need not preclude the idea Marlowe was at times seriously engaged with the tragic aspect of his subject, and the play is seen as tragical satire.
Properties of Binary Transition-Metal Arsenides (TAs)
Creators: name: Saparov, B.
name: Mitchell, J. E.
name: Sefat, A. S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present thermodynamic and transport properties of transition-metal (T) arsenides, TAs with T = Sc to Ni (3d), Zr, Nb, Ru (4d), Hf and Ta (5d). Characterization of these binaries is made with powder X-ray diffraction, temperature and field-dependent magnetization and resistivity, temperature-dependent heat capacity, Seebeck coefficient, and thermal conductivity. All binaries show metallic behavior except TaAs and RuAs. TaAs, NbAs, ScAs and ZrAs are diamagnetic, while CoAs, VAs, TiAs, NiAs and RuAs show approximately Pauli paramagnetic behavior. FeAs and CrAs undergo antiferromagnetic order below TN = 71 K and TN \approx 260 K, respectively. MnAs is a ferromagnet below TC = 317 K and undergoes hexagonal-orthorhombic-hexagonal transitions at TS = 317 K and 384 K, respectively. For TAs, Seebeck coefficients vary between + 40 uV/K and - 40 uV/K in the 2 K to 300 K range, whereas thermal conductivity values stay below 18 W/(m K). The Sommerfeld-coefficient γ are less than 10 mJ/(K2mol). At room temperature with application of 8 Tesla magnetic field, large positive magnetoresistance is found for TaAs (~25%), MnAs (~90%) and for NbAs (~75%).
description: 7 figures; Will be published in the upcoming focus issue in Superconductor Science and Technology
Report from the "What Is Open?" Workgroup
Creators: name: Anderson, Rick
name: Denbo, Seth
name: Graves, Diane
name: Haigh, Susan
name: Hill, Steven
name: Kalfatovic, Martin
name: Kaufman, Roy
name: Murray-Rust, Catherine
name: Shearer, Kathleen
name: Wilder, Dick
name: Wise, Alicia
Publisher: name: Open Scholarship Initiative Proceedings
Year: 2016

description: The scholarly communityâ€™s current definition of â€œopenâ€ captures only some of the attributes of openness that exist across different publishing models and content types. Open is not an end in itself, but a means for achieving the most effective dissemination of scholarship and research. We suggest that the different attributes of open exist along a broad spectrum and propose an alternative way of describing and evaluating openness based on four attributes: discoverable, accessible, reusable, and transparent. These four attributes of openness, taken together, form the draft â€œDART Framework for Open Access.â€ This framework can be applied to both research artifacts as well as research processes. We welcome input from the broader scholarly community about this framework.
OSI2016 workgroup questionThere is a broad difference of opinion among the many stakeholders in scholarly publishing about how to precisely define open access publishing. Are â€œopen accessâ€ and â€œopen dataâ€ what we mean by open? Does â€œopenâ€ mean anything else? Does it mean â€œto make available,â€ or â€œto make freely available in a particular format?â€ Is a clearer definition needed (or maybe just better education on the current definition)? Why or why not? At present, some stakeholders see public access as being an acceptable stopping point in the move toward open access. Others see â€œopenâ€ as requiring free and immediate access with articles being available in CC-BY format. The range of opinions between these extremes is vast. How should these differences be decided? Who should decide? Is it possible to make binding recommendations (and how)? Is consensus necessary? What are the consequences of the lack of consensus?
description: Open Scholarship Initiative Proceedings, 2016
Bright solitons from defocusing nonlinearities
Creators: name: Borovkova, Olga V.
name: Kartashov, Yaroslav V.
name: Torner, Lluis
name: Malomed, Boris A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optics (physics.optics)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We report that defocusing cubic media with spatially inhomogeneous nonlinearity, whose strength increases rapidly enough toward the periphery, can support stable bright localized modes. Such nonlinearity landscapes give rise to a variety of stable solitons in all three dimensions, including 1D fundamental and multihump states, 2D vortex solitons with arbitrarily high topological charges, and fundamental solitons in 3D. Solitons maintain their coherence in the state of motion, oscillating in the nonlinear potential as robust quasi-particles and colliding elastically. In addition to numerically found soliton families, particular solutions are found in an exact analytical form, and accurate approximations are developed for the entire families, including moving solitons.
description: 13 pages, 6 figures, to appear in Physical Review E
Paving the Way to Overcome Antifungal Drug Resistance: Current Practices and Novel Developments for Rapid and Reliable Antifungal Susceptibility Testing
Creators: name: Heuer, Christopher
name: Bahnemann, Janina
name: Scheper, Thomas
name: Segal, Ester
Publisher: name: Weinheim : WILEY-VCH Verlag GmbH & Co. KGaA
Year: 2021
Subjects: subject: diagnostics
subject: drug resistance
subject: fungal pathogens
subject: microfluidics
subject: rapid antifungal susceptibility testing
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: The past year has established the link between the COVID-19 pandemic and the global spread of severe fungal infections; thus, underscoring the critical need for rapid and realizable fungal disease diagnostics. While in recent years, health authorities, such as the Centers for Disease Control and Prevention, have reported the alarming emergence and spread of drug-resistant pathogenic fungi and warned against the devastating consequences, progress in the diagnosis and treatment of fungal infections is limited. Early diagnosis and patient-tailored therapy are established to be key in reducing morbidity and mortality associated with fungal (and cofungal) infections. As such, antifungal susceptibility testing (AFST) is crucial in revealing susceptibility or resistance of these pathogens and initiating correct antifungal therapy. Today, gold standard AFST methods require several days for completion, and thus this much delayed time for answer limits their clinical application. This review focuses on the advancements made in developing novel AFST techniques and discusses their implications in the context of the practiced clinical workflow. The aim of this work is to highlight the advantages and drawbacks of currently available methods and identify the main gaps hindering their progress toward clinical application.
Occupant comfort and engagement in green buildings : examining the effects of knowledge, feedback and workplace culture
Creators: name: Brown, Zofia Birgit
Publisher: name: University of British Columbia
Year: 2010

description: Buildings are seen as a key potential contributor to the mitigation of climate change, spurring increased attention in recent years to their design, performance and evaluation. The successful delivery of green buildings requires balancing energy and resource efficiency while providing a comfortable, healthy and productive environment within economic means. Occupant comfort and behaviour can have a significant impact on green building performance, and yet very little is known about how their comfort is shaped and behavioral patterns formed, particularly in the commercial setting. Through the post-occupancy evaluation of six Canadian office buildings, three green and three conventionally designed, this thesis examines the behavioural, socio-psychological and contextual factors that influence comfort and user engagement in green buildings. In Chapter 2, occupants’ knowledge of how the building performs and comfort is provided is compared to an expert baseline, and a gap identified between their expressed desire to learn and the information available to them. Comfort is viewed both as a trigger of changes to user behaviour (discomfort leads to action) and an outcome from changes to user behaviour (action leads to improved or diminished comfort). In Chapter 3, the incorporation of feedback into building design, implementation and use is compared for two green buildings, and found to influence occupants’ self-rated knowledge of the building, perceptions of building performance, and use of controls and complaints. Lack of effective feedback in one of the buildings leads occupants to view themselves as passive (rather than active) participants in establishing comfort conditions. In Chapter 4, a company’s move from a conventional to a green building is examined through the lens of cultural and contextual factors shaping design and operation decisions. These factors are shown to potentially significantly influence occupant comfort and behavior in the new building, with gains in satisfaction and productivity difficult to disentangle from green building or workplace design factors. Combined, these results provide evidence that knowledge, expectations, feedback and culture all play an important role in shaping occupant comfort and comfort-related behaviour in green buildings, and shed light on the limitations of current post-occupancy evaluation method to capture the complexities of user experience.
Inclusive dielectron spectra in p+p collisions at 3.5 GeV
Creators: name: Agakishiev, G.
name: Balanda, A.
name: Belver, D.
name: Belyaev, A.
name: Blanco, A.
name: Böhmer, M.
name: Boyard, J. L.
name: Cabanelas, P.
name: Castro, E.
name: Chen, J. C.
name: Chernenko, S.
name: Christ, T.
name: Destefanis, M.
name: Dohrmann, F.
name: Dybczak, A.
name: Epple, E.
name: Fabbietti, L.
name: Fateev, O.
name: Finocchiaro, P.
name: Fonte, P.
name: Friese, J.
name: Fröhlich, I.
name: Galatyuk, T.
name: Garzón, J. A.
name: Gernhäuser, R.
name: Gilardi, C.
name: Golubeva, M.
name: González-Díaz, D.
name: Guber, F.
name: Gumberidze, M.
name: Heinz, T.
name: Hennino, T.
name: Holzmann, R.
name: Iori, I.
name: Ivashkin, A.
name: Jurkovic, M.
name: Kämpfer, B.
name: Kanaki, K.
name: Karavicheva, T.
name: Koenig, I.
name: Koenig, W.
name: Kolb, B. W.
name: Kotte, R.
name: Krása, A.
name: Krizek, F.
name: Krücken, R.
name: Kuc, H.
name: Kühn, W.
name: Kugler, A.
name: Kurepin, A.
name: Lalik, R.
name: Lang, S.
name: Lange, J. S.
name: Lapidus, K.
name: Liu, T.
name: Lopes, L.
name: Lorenz, M.
name: Maier, L.
name: Mangiarotti, A.
name: Markert, J.
name: Metag, V.
name: Michalska, B.
name: Michel, J.
name: Morinière, E.
name: Mousa, J.
name: Müntz, C.
name: Naumann, L.
name: Otwinowski, J.
name: Pachmayer, Y. C.
name: Palka, M.
name: Parpottas, Y.
name: Pechenov, V.
name: Pechenova, O.
name: Pietraszko, J.
name: Przygoda, W.
name: Ramstein, B.
name: Reshetin, A.
name: Rustamov, A.
name: Sadovsky, A.
name: Salabura, P.
name: Schmah, A.
name: Schwab, E.
name: Siebenson, J.
name: Sobolev, Yu. G.
name: Spataro, S.
name: Spruck, B.
name: Ströbele, H.
name: Stroth, J.
name: Sturm, C.
name: Tarantola, A.
name: Teilab, K.
name: Tlusty, P.
name: Traxler, M.
name: Trebacz, R.
name: Tsertos, H.
name: Wagner, V.
name: Weber, M.
name: Wendisch, C.
name: Wüstenfeld, J.
name: Yurevich, S.
name: Zanevsky, Y.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We present the inclusive invariant-mass, transverse momentum and rapidity distributions of dielectrons (e$^{+}$e$^{-}$ pairs) in p+p interactions at 3.5 GeV beam kinetic energy. In the vector-meson mass region, a distinct peak corresponding to direct $ω$ decays is reconstructed with 2% mass resolution. The data is compared to predictions from three model calculations. Due to the large acceptance of the HADES apparatus for $e^{+}e^{-}$ invariant masses above 0.2 GeV/$c^{2}$ and for transverse pair momenta p$_{t}$ $
Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung
Creators: name: Lüdtke, Timo H.
name: Wojahn, Irina
name: Kleppa, Marc-Jens
name: Schierstaedt, Jasper
name: Christoffels, Vincent M.
name: Künzler, Patrick
name: Kispert, Andreas
Publisher: name: London : BioMed Central
Year: 2021
Subjects: subject: CBX3
subject: HDAC
subject: HMGB2
subject: Lung development
subject: NuRD
subject: PBX1
subject: Pulmonary mesenchyme
subject: Tbx2
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit

description: Background: Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was traced to direct repression of the cell-cycle inhibitor genes Cdkn1a and Cdkn1b, as well as of genes encoding WNT antagonists, Frzb and Shisa3, to increase pro-proliferative WNT signaling. Despite these important molecular insights, we still lack knowledge of the DNA occupancy of TBX2 in the genome, and of the protein interaction partners involved in transcriptional repression of target genes. Methods: We used chromatin immunoprecipitation (ChIP)-sequencing and expression analyses to identify genomic DNA-binding sites and transcription units directly regulated by TBX2 in the developing lung. Moreover, we purified TBX2 containing protein complexes from embryonic lung tissue and identified potential interaction partners by subsequent liquid chromatography/mass spectrometry. The interaction with candidate proteins was validated by immunofluorescence, proximity ligation and individual co-immunoprecipitation analyses. Results: We identified Il33 and Ccn4 as additional direct target genes of TBX2 in the pulmonary mesenchyme. Analyzing TBX2 occupancy data unveiled the enrichment of five consensus sequences, three of which match T-box binding elements. The remaining two correspond to a high mobility group (HMG)-box and a homeobox consensus sequence motif. We found and validated binding of TBX2 to the HMG-box transcription factor HMGB2 and the homeobox transcription factor PBX1, to the heterochromatin protein CBX3, and to various members of the nucleosome remodeling and deacetylase (NuRD) chromatin remodeling complex including HDAC1, HDAC2 and CHD4. Conclusion: Our data suggest that TBX2 interacts with homeobox and HMG-box transcription factors as well as with the NuRD chromatin remodeling complex to repress transcription of anti-proliferative genes in the pulmonary mesenchyme.
The effect of long term hypoxia on growth and development of the respiratory mechanism of larval Arctic char, Salvelinus alpinus
Creators: name: McDonald, David Gordon
Publisher: name: University of Calgary
Year: 1974
Subjects: subject: QL 638 S2 M16 1974 Microfiche
subject: Arctic char
subject: Salvelinus alpinus
subject: Gills
subject: Oxygen - Physiological effect

description: Bibliography: p. 76-81.
Openglamur - Kulturdaten Für Forschung Und Universitäten
Creators: name: Bruhn, Kai-Christian
Publisher: name: Zenodo
Year: 2016
Subjects: GLAM
OpenGLAM
Landscape Archaeology
Digital Scholarship
Open Science
Linked Open Data

description: Impulsvortrag auf RMX CULTURA @Denkfest Mannheim am 9. Juni 2016

Presentation on the occasion of RMX CULTURA @Denkfest Mannheim, June 9th, 2016
Kummer surfaces and the computation of the Picard group
Creators: name: Elsenhans, Andreas-Stephan
name: Jahnel, Jörg
Publisher: name: arXiv
Year: 2011
Subjects: subject: Algebraic Geometry (math.AG)
subject: Complex Variables (math.CV)
subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 14J28, 14C22, 14K99, 14F20

description: We test R. van Luijk's method for computing the Picard group of a $K3$ surface. The examples considered are the resolutions of Kummer quartics in $\bP^3$. Using the theory of abelian varieties, in this case, the Picard group may be computed directly. Our experiments show that the upper bounds provided by R. van Luijk's method are sharp when sufficiently many primes are used. In fact, there are a lot of primes that yield a value close to the exact one. However, for many but not all Kummer surfaces $V$ of Picard rank 18, we have $\smash{\rk\Pic(V_{\bar\bbF_{p}}) \geq 20}$ for a set of primes of density $\geq 1/2$.
description: This article is unchanged. This is just a second trial to upload our raw data to the Data Conservancy project
A variability study of the AGILE first catalog of γ-ray sources on 2.3 years of AGILE pointed observations
Creators: name: Verrecchia, F.
name: Pittori, C.
name: Bulgarelli, A.
name: Chen, A. W.
name: Tavani, M.
name: Lucarelli, F.
name: Giommi, P.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: AGILE pointed observations performed from July 9, 2007 to October 30, 2009 cover a very large time interval, with a γ-ray dataset useful to perform studies of medium to high brightness galactic sources in the 30 MeV -- 50 GeV energy range. We present a study of the 1AGL galactic sources in the E > 100 MeV band, over the complete Agile pointed Observation Blocks (OBs) archive. The first AGILE Gamma-Ray Imaging Detector (GRID) catalog included a sample of 47 sources (1AGL; Pittori et al. 2009), detected with a conservative analysis over the first year of operations dataset. In the analysis here reported we used data obtained with an improved full Field of View (FOV) event filter, on a much larger (about 27.5 months) observation dataset, analyzing the merging of all data and each OB separately. The data processing resulted in an improved source list as compared to the 1AGL one, particularly in complex regions of the galactic plane. We present here some results on the revised 1AGL galactic sources and on the variability of some of them.
description: 2011 Fermi Symposium proceedings - eConf C110509
Additional file 1 of The induction effect of hydroxyurea and metformin on fetal globin in the K562 cell line
Creators: name: Eini, Mohammad
name: Safarpour, Hossain
name: Miri-Moghddam, Ebrahim
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Astronomical and Space Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Supplementary Material 1
Data-based ensemble approach for semi-supervised anomaly detection in machine tool condition monitoring
Creators: name: Denkena, B.
name: Dittrich, M.-A.
name: Noske, H.
name: Stoppel, D.
name: Lange, D.
Publisher: name: Amsterdam [u.a.] : Elsevier
Year: 2021
Subjects: subject: Ball screw
subject: Condition monitoring
subject: Failure
subject: Machine learning
subject: Maintenance
subject: Dewey Decimal Classification::600 | Technik

description: Data-based methods are capable to monitor machine components. Approaches for semi-supervised anomaly detection are trained using sensor data that describe the normal state of machine components. Thus, such approaches are interesting for industrial practice, since sensor data do not have to be labeled in a time-consuming and costly way. In this work, an ensemble approach for semi-supervised anomaly detection is used to detect anomalies. It is shown that the ensemble approach is suitable for condition monitoring of ball screws. For the evaluation of the approach, a data set of a regular test cycle of a ball screw from automotive industry is used.
The Harps-N Red Dwarf Exoplanets Survey (Hades) - Time Resolved Spectroscopic Analysis Of The Steady Chromosphere Of Low-Activity Early-M Dwarfs
Creators: name: Scandariato, Gaetano
Publisher: name: Zenodo
Year: 2016
Subjects: stars
dwarfs
chromosphere
active regions
spectroscopy

description: We analyze the spectra of the quiet early-M dwarfs that the HADES project monitored for 3.5 years. The wavelength range covered by the spectra allows us to analyze simultaneously the CaII H&K doublet and the Hα line, while the intensive

follow up gives us a large number of spectra (up to ~100) for each targeted star. We show how the CaII H&K and Hα fluxes are correlated at low activity levels and we infer the evolution timescales of chromospheric active regions.
Earth Observation Data-Driven Cropland Soil Monitoring: A Review
Creators: name: Tziolas, Nikolaos
name: Tsakiridis, Nikolaos
name: Chabrillat, Sabine
name: Demattê, José A. M.
name: Ben-Dor, Eyal
name: Gholizadeh, Asa
name: Zalidis, George
name: Van Wesemael, Bas
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: Carbon farming
subject: Common agricultural policy
subject: Deep learning
subject: Earth observation
subject: Food security
subject: Hyperspectral
subject: Soil organic carbon
subject: Spectral signatures
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: We conducted a systematic review and inventory of recent research achievements related to spaceborne and aerial Earth Observation (EO) data-driven monitoring in support of soil-related strategic goals for a three-year period (2019–2021). Scaling, resolution, data characteristics, and modelling approaches were summarized, after reviewing 46 peer-reviewed articles in international journals. Inherent limitations associated with an EO-based soil mapping approach that hinder its wider adoption were recognized and divided into four categories: (i) area covered and data to be shared; (ii) thresholds for bare soil detection; (iii) soil surface conditions; and (iv) infrastructure capabilities. Accordingly, we tried to redefine the meaning of what is expected in the next years for EO data-driven topsoil monitoring by performing a thorough analysis driven by the upcoming technological waves. The review concludes that the best practices for the advancement of an EO data-driven soil mapping include: (i) a further leverage of recent artificial intelligence techniques to achieve the desired representativeness and reliability; (ii) a continued effort to share harmonized labelled datasets; (iii) data fusion with in situ sensing systems; (iv) a continued effort to overcome the current limitations in terms of sensor resolution and processing limitations of this wealth of EO data; and (v) political and administrative issues (e.g., funding, sustainability). This paper may help to pave the way for further interdisciplinary research and multi-actor coordination activities and to generate EO-based benefits for policy and economy.
Piper crocatum Ruiz & Pav. ameliorates wound healing through p53, E-cadherin and SOD1 pathways on wounded hyperglycemia fibroblasts
Creators: name: Setyawati, Andina
name: Wahyuningsih, Mae Sri Hartati
name: Nugrahaningsih, Dwi Aris Agung
name: Effendy, Christantie
name: Fneish, Firas
name: Fortwengel, Gerhard
Publisher: name: Amsterdam [u.a.] : Elsevier
Year: 2021
Subjects: subject: Diabetic wound healing
subject: E-cadherin
subject: Mechanism
subject: p53
subject: Piper crocatum Ruiz & Pav
subject: SOD1
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: Introduction: Piper crocatum Ruiz & Pav (P. crocatum) has been reported to accelerate the diabetic wound healing process empirically. Some studies showed the benefits of P. crocatum in treating various diseases but its mechanisms in diabetic wound healing have never been reported. In the present study we investigated the diabetic wound healing activity of the active fraction of P. crocatum on wounded hyperglycemia fibroblasts (wHFs). Methods: Bioassay-guided fractionation was performed to get the most active fraction. The selected active fraction was applied to wHFs within 72 h incubation. Mimicking a diabetic condition was done using basal glucose media containing an additional 17 mMol/L D-glucose. A wound was simulated via the scratch assay. The collagen deposition was measured using Picro-Sirius Red and wound closure was measured using scratch wound assay. Underlying mechanisms through p53, αSMA, SOD1 and E-cadherin were measured using western blotting. Results: We reported that FIV is the most active fraction of P. crocatum. We confirmed that FIV\(7.81 µg/ml, 15.62 µg/ml, 31.25 µg/ml, 62.5 µg/ml, and 125 µg/ml) induced the collagen deposition and wound closure of wHFs. Furthermore, FIV treatment (7.81 µg/ml, 15.62 µg/ml, 31.25 µg/ml) down-regulated the protein expression level of p53 and up-regulated the protein expression levels of αSMA, E-cadherin, and SOD1. Discussion/conclusions: Our findings suggest that ameliorating collagen deposition and wound closure through protein regulation of p53, αSMA, E-cadherin, and SOD1 are some of the mechanisms by which FIV of P. crocatum is involved in diabetic wound healing therapy.
Characterizations of distributions via order statistics with random exponential shifts
Creators: name: Ahsanullah, M.
name: Nevzorov, V. B.
name: Yanev, George P.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Probability (math.PR)
subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: 62G30

description: A class of probability distributions is characterized via equalities in law between two order statistics shifted by independent exponential variables. An explicit formula for the quintile function of the identified family of distributions is obtained. The results extend some known characterizations of exponential and logistic distributions.
Erwartung An Forschungsunterstützung: Geistes- Und Kulturwissenschaften
Creators: name: Klammt, Anne
Publisher: name: Zenodo
Year: 2016
Subjects: Virtuelle Forschungsumgebung
Digital Humanities
Geisteswissesnchaften

description: Vortrag anlässlich des Workshops "Adaptive Dienstleistungen zur Unterstützung von Science 2.0", Universitätsbibliothek der Technischen Universität München, 9.-11. September 2015
Fused Deposition Modeling of Microfluidic Chips in Transparent Polystyrene
Creators: name: Mader, Markus
name: Rein, Christof
name: Konrat, Eveline
name: Meermeyer, Sophia Lena
name: Lee-Thedieck, Cornelia
name: Kotz-Helmer, Frederik
name: Rapp, Bastian E.
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: 3D printing
subject: Additive manufacturing
subject: Cell cultures
subject: Fused deposition modeling
subject: Microfluidics
subject: Polystyrene
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: Polystyrene (PS) is one of the most commonly used thermoplastic materials worldwide and plays a ubiquitous role in today’s biomedical and life science industry and research. The main advantage of PS lies in its facile processability, its excellent optical and mechanical properties, as well as its biocompatibility. However, PS is only rarely used in microfluidic prototyping, since the structuring of PS is mainly performed using industrial-scale replication processes. So far, microfluidic chips in PS have not been accessible to rapid prototyping via 3D printing. In this work, we present, for the first time, 3D printing of transparent PS using fused deposition modeling (FDM). We present FDM printing of transparent PS microfluidic channels with dimensions as small as 300 µm and a high transparency in the region of interest. Furthermore, we demonstrate the fabrication of functional chips such as Tesla-mixer and mixer cascades. Cell culture experiments showed a high cell viability during seven days of culturing, as well as enabling cell adhesion and proliferation. With the aid of this new PS prototyping method, the development of future biomedical microfluidic chips will be significantly accelerated, as it enables using PS from the early academic prototyping all the way to industrial-scale mass replication.
Self-Assembled Nanoparticles Based on Block-Copolymers of Poly(2-Deoxy-2-methacrylamido-d-glucose)/Poly(N-Vinyl Succinamic Acid) with Poly(O-Cholesteryl Methacrylate) for Delivery of Hydrophobic Drugs
Creators: name: Levit, Mariia
name: Vdovchenko, Alena
name: Dzhuzha, Apollinariia
name: Zashikhina, Natalia
name: Katernyuk, Elena
name: Gostev, Alexey
name: Sivtsov, Eugene
name: Lavrentieva, Antonina
name: Tennikova, Tatiana
name: Korzhikova-Vlakh, Evgenia
Publisher: name: Basel : Molecular Diversity Preservation International
Year: 2021
Subjects: subject: Amphiphilic copolymers
subject: Bio-inspired copolymers
subject: Block-copolymers
subject: Controlled radical polymerization
subject: Drug delivery systems
subject: Paclitaxel delivery
subject: Polymer nanoparticles
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The self-assembly of amphiphilic block-copolymers is a convenient way to obtain soft nanomaterials of different morphology and scale. In turn, the use of a biomimetic approach makes it possible to synthesize polymers with fragments similar to natural macromolecules but more resistant to biodegradation. In this study, we synthesized the novel bio-inspired amphiphilic block-copolymers consisting of poly(N-methacrylamido-D-glucose) or poly(N-vinyl succinamic acid) as a hydrophilic fragment and poly(O-cholesteryl methacrylate) as a hydrophobic fragment. Block-copolymers were synthesized by radical addition–fragmentation chain-transfer (RAFT) polymerization using dithiobenzoate or trithiocarbonate chain-transfer agent depending on the first monomer, further forming the hydrophilic block. Both homopolymers and copolymers were characterized by1 H NMR and Fourier transform infrared spectroscopy, as well as thermogravimetric analysis. The obtained copolymers had low dispersity (1.05–1.37) and molecular weights in the range of ~13,000–32,000. The amphiphilic copolymers demonstrated enhanced thermal stability in comparison with hydrophilic precursors. According to dynamic light scattering and nanoparticle tracking analysis, the obtained amphiphilic copolymers were able to self-assemble in aqueous media into nanoparticles with a hydrodynamic diameter of approximately 200 nm. An investigation of nanoparticles by transmission electron microscopy revealed their spherical shape. The obtained nanoparticles did not demonstrate cytotoxicity against human embryonic kidney (HEK293) and bronchial epithelial (BEAS-2B) cells, and they were characterized by a low uptake by macrophages in vitro. Paclitaxel loaded into the developed polymer nanoparticles retained biological activity against lung adenocarcinoma epithelial cells (A549).