cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Improving Reconstruction Of Gev-Scale Neutrinos In Icecube-Deepcore By Direct Event Simulation
Creators: name: NOWICKI, Sarah
Publisher: name: Zenodo
Year: 2018

description: Detection of few-GeV atmospheric neutrinos is made possible by the DeepCore infill array to the IceCube detector. The relatively small amount of recorded event information at these energies introduces challenges for the reconstruction of particle properties, such as energy and incoming angle. Further, the naturally-occurring deep glacial Cherenkov medium requires detailed models, based on in-situ calibrations, to describe photon propagation in the ice. Current reconstruction methods rely on approximated tabulated template events. Replacing these templates with event simulation allows use of the full description of the natural ice medium for accurate resolution of event properties. This method of "direct reconstruction" can also be used for study of ice-related systematic errors. A full description of the algorithm, as well as an estimation of its effects on event reconstruction will be presented.
Additional file 2 of Exploring the needs and coping strategies of family caregivers taking care of dying patients at home: a field study
Creators: name: Zhang, Xiaotian
name: Xu, Tianmeng
name: Qin, Yuan
name: Wang, Minghui
name: Li, Zhaoyu
name: Song, Jingyu
name: Tang, Qianqian
name: Wang, Zidan
name: Xu, Lijie
name: Wu, Lingling
name: Yue, Peng
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 2
The Higgs Vacuum Uplifted: Revisiting the Electroweak Phase Transition with a Second Higgs Doublet
Creators: name: Carvalho Dorsch, Gláuber
name: Huber, S. J.
name: Mimasu, K.
name: No, J. M.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017
Subjects: electroweak interaction: critical phenomena
Higgs particle: doublet
CERN LHC Coll
asymmetry

description: The existence of a second Higgs doublet in Nature could lead to a cosmological first order electroweak phase transition and explain the origin of the matter-antimatter asymmetry in the Universe. We explore the parameter space of such a two-Higgs-doublet-model and show that a first order electroweak phase transition strongly correlates with a significant uplifting of the Higgs vacuum w.r.t. its Standard Model value. We then obtain the spectrum and properties of the new scalars $H_0$, $A_0$ and $H^{\pm}$ that signal such a phase transition, showing that the decay $A_0 \rightarrow H_0 Z$ at the LHC and a sizable deviation in the Higgs self-coupling $\lambda_{hhh}$ from its SM value are sensitive indicators of a strongly first order electroweak phase transition in the 2HDM.
Combination of beauty and charm production cross section measurements in deep inelastic ep scattering at HERA
Creators: name: Zenaiev, Oleksandr
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017

description: XXV International Workshop on Deep-Inelastic Scattering and Related Subjects, DIS2017, Birmingham, United Kingdom, 3 Apr 2017 - 7 Apr 2017
sj-docx-1-cpc-10.1177_10556656221149521 - Supplemental material for Unraveling a Major Burden of Orofacial Clefts Analyses: Classification of Cleft Palate Fistulas by Cleft Surgeons
Creators: name: Houkes, Ruben P.
name: Smit, Johannes A.
name: Lachkar, N.
name: Tse, Raymond
name: Breugem, Corstiaan C.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-cpc-10.1177_10556656221149521 for Unraveling a Major Burden of Orofacial Clefts Analyses: Classification of Cleft Palate Fistulas by Cleft Surgeons by Ruben P. Houkes, Johannes A. Smit, N. Lachkar, Raymond Tse and Corstiaan C. Breugem in The Cleft Palate Craniofacial Journal
Climate drives the geography of marine consumption by changing predator communities
Creators: name: Verges, Adriana
name: Lefcheck, Jonathan S.
name: Cusson, Mathieu
name: Reiss, Katrin
name: Janiak, Dean S.
name: Diskin, Meredith S.
name: Alcoverro, Teresa
name: Hughes, A. Randall
name: Whippo, Ross D. B.
name: Flores, Augusto A. V.
name: Macreadie, Peter I.
name: Monteith, Zachary L.
name: Altieri, Andrew H.
name: Johnston, Lane N.
name: Graham, Olivia J.
name: Yednock, Bree K.
name: O'Connor, Nessa E.
name: Benedetti-Cecchi, Lisandro
name: Hanley, Torrance C.
name: Lozano-Alvarez, Enrique
name: Robinson, Max T.
name: D'Souza, Elrika
name: Hultgren, Kristin M.
name: Silliman, Brian R.
name: Jorgensen, Pablo
name: Poore, Alistair G. B.
name: Duffy, J. Emmett
name: Ziegler, Shelby L.
name: Kruschel, Claudia
name: Henderson, Christopher J.
name: Bertolini, Camilla
name: Rhoades, O. Kennedy
name: Ross, Paige G.
name: Bulleri, Fabio
name: Smee, Delbert L.
name: Cimon, Stephanie
name: Hessing-Lewis, Margot
name: Lee, Kun-Seop
name: Galloway, Aaron W. E.
name: Fodrie, F. Joel
name: Connolly, Rod M.
name: Kelaher, Brendan P.
name: Patrick, Christopher J.
name: Pino, Oscar
name: Stachowicz, John J.
name: Whalen, Matthew A.
name: Aiello, Erin
name: Olds, Andrew D.
name: O'Leary, Jennifer K.
name: Schlacher, Thomas A.
name: Lanham, Brendan S.
name: Bresch, Midoli
name: Hereu, Clara M.
name: Carnell, Paul E.
name: Thiel, Martin
name: Rossi, Francesca
name: van Tussenbroek, Brigitta I.
name: Hovel, Kevin A.
name: Jaenes, Holger
name: York, Paul H.
name: Hughes, Brent B.
name: Rasheed, Michael A.
name: Gaskins, Leo C.
name: Seemann, Janina
name: Yeager, Mallarie E.
name: Raymond, Wendel W.
name: Unsworth, Richard K. F.
Publisher: name: Proceedings of the National Academy of Sciences
Year: 2020

description: The global distribution of primary production and consumption by humans (fisheries) is well-documented, but we have no map linking the central ecological process of consumption within food webs to temperature and other ecological drivers. Using standardized assays that span 105° of latitude on four continents, we show that rates of bait consumption by generalist predators in shallow marine ecosystems are tightly linked to both temperature and the composition of consumer assemblages. Unexpectedly, rates of consumption peaked at midlatitudes (25 to 35°) in both Northern and Southern Hemispheres across both seagrass and unvegetated sediment habitats. This pattern contrasts with terrestrial systems, where biotic interactions reportedly weaken away from the equator, but it parallels an emerging pattern of a subtropical peak in marine biodiversity. The higher consumption at midlatitudes was closely related to the type of consumers present, which explained rates of consumption better than consumer density, biomass, species diversity, or habitat. Indeed, the apparent effect of temperature on consumption was mostly driven by temperature-associated turnover in consumer community composition. Our findings reinforce the key influence of climate warming on altered species composition and highlight its implications for the functioning of Earth's ecosystems.
sj-docx-2-cpc-10.1177_10556656221148901 - Supplemental material for Predictors of Adverse Outcomes Following Cleft Palate Repair: An Analysis of Over 2500 Patients Using International Smile Train Data
Creators: name: Chwa, Emily S.
name: Stoehr, Jenna R.
name: Gosain, Arun K.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-2-cpc-10.1177_10556656221148901 for Predictors of Adverse Outcomes Following Cleft Palate Repair: An Analysis of Over 2500 Patients Using International Smile Train Data by Emily S. Chwa, Jenna R. Stoehr and Arun K. Gosain in The Cleft Palate Craniofacial Journal
Potencjał dzeta łupka miedzionośnego w wodnych roztworach kolektorów oraz spieniaczy
Creators: name: Kruszelnicki, Mateusz
name: Polowczyk, Izabela
name: Kowalczuk, Przemysław B.
Publisher: name: Faculty of Geoengineering, Mining and Geology, Wrocław University of Technology, Wrocław
Year: 2017
Subjects: łupek miedzionośny, kolektor, spieniacz

description: Łupek miedzionośny III, Kowalczuk P.B., Drzymała J. (red.), WGGG PWr, Wrocław, ISBN 978-83-946706-0-3
Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma
Creators: name: Hollingsworth, Michael A
name: Wang, Zhen
name: True-Yasaki, Aisha
name: Anderson, Judy M
name: Collisson, Eric A
name: Rashid, Naim
name: Torphy, Robert J
name: Yeh, Jen Jen
name: Yeh, Benjamin
name: Volmar, Keith E
name: Johansen, Julia S
Publisher: name: American Society of Clinical Oncology (ASCO)
Year: 2018

description: PURPOSE: Desmoplastic stroma is a cardinal feature of primary pancreatic ductal adenocarcinoma (PDAC), but its effects on the biology, prognosis and therapeutic outcomes are not known. We developed an automated method to assess tumor stroma density (TSD) and investigated computed tomography (CT)-correlates of stroma in PDAC. PATIENTS AND METHODS: We collected PDAC samples from rapid autopsy and resection series and digitally annotated samples to quantify TSD. A series of resected patients also underwent preoperative multiphasic CT. RESULTS: Automated and manual assessments of TSD were highly correlated (Ïa= 0.65, P < 0.001). Solid organ metastases had a lower median TSD than primary tumors (P < 0.001). Patients with high TSD enjoyed prolonged recurrence free survival (RFS) (P = 0.003; HR = 0.51) and overall survival (P = 0.008, HR = 0.57). In another independent dataset, patients with high TSD had decreased risk for recurrence (P = 0.003, HR = 0.03) and death (P = 0.003, HR = 0.03) at time of resection, however the protective effect diminished over time. Patients with normalized portovenous phase CT tumor enhancement ratio ≥0.40 had a longer RFS following resection (P = 0.020). Normalized portovenous phase CT tumor enhancement ratio was significantly correlated with TSD (P = 0.003). CONCLUSIONS: Objective quantitative assessment of stroma in PDAC revealed several clinically relevant observations. Firstly, stroma was less abundant in metastatic PDAC, the cause of most PDAC mortality. Secondly, high stromal content correlates with favorable outcome in resected cases, implying a protective effect of stroma and suggesting careful consideration of active stromal depletion therapies. Finally, standard multiphase CT imaging correlates with stroma content as well as clinical outcome, indicating that non-invasive assessment of stroma is a feasible sensitivity enrichment approach in PDAC.
National (In)Security: Constructing the Nation-State through Statelessness and the Non-Provision of Rights
Creators: name: ADAM ALMOG ZIMBLER
Publisher: name: Monash University
Year: 2020
Subjects: subject: Law
subject: FOS: Law

description: This thesis examines the unacceptable situation where human rights are made subject to the nation-state's need for a high degree of internal cohesion, which it achieves through Othering and the exclusion of groups deemed incompatible with the unified national identity. This situation is the result of a weak international legal framework, which proclaims the universality of human rights, but depends upon nation-states for their provision. The effect of this is felt most profoundly by stateless persons, who lack citizenship and its attendant rights, and thus constitute the nation-state's paradigmatic Other.
sj-docx-4-cpc-10.1177_10556656221148901 - Supplemental material for Predictors of Adverse Outcomes Following Cleft Palate Repair: An Analysis of Over 2500 Patients Using International Smile Train Data
Creators: name: Chwa, Emily S.
name: Stoehr, Jenna R.
name: Gosain, Arun K.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-4-cpc-10.1177_10556656221148901 for Predictors of Adverse Outcomes Following Cleft Palate Repair: An Analysis of Over 2500 Patients Using International Smile Train Data by Emily S. Chwa, Jenna R. Stoehr and Arun K. Gosain in The Cleft Palate Craniofacial Journal
Impact of Regulatory T Cells on Type 2 Alveolar Epithelial Cell Transcriptomes during Resolution of Acute Lung Injury and Contributions of IFN-γ.
Creators: name: Dang, Hong
name: Dial, Catherine F
name: Tune, Miriya K
name: Mock, Jason R
name: Doerschuk, Claire M
name: O'Neal, Wanda K
name: Gilmore, Rodney C
Publisher: name: American Thoracic Society
Year: 2020

description: By enhancing tissue repair and modulating immune responses, Foxp3+ regulatory T cells (Tregs) play essential roles in resolution from lung injury. The current study investigated the effects that Tregs exert directly or indirectly on the transcriptional profiles of type 2 alveolar epithelial (AT2) cells during resolution in an experimental model of acute lung injury. Purified AT2 cells were isolated from uninjured mice or mice recovering from LPS-induced lung injury, either in the presence of Tregs or in Treg-depleted mice, and transcriptome profiling identified differentially expressed genes. Depletion of Tregs resulted in altered expression of 49 genes within AT2 cells during resolution, suggesting that Tregs present in this microenvironment influence AT2-cell function. Biological processes from Gene Ontology enriched in the absence of Tregs included those describing responses to IFN. Neutralizing IFN-γ in Treg-depleted mice reversed the effect of Treg depletion on inflammatory macrophages and B cells by preventing the increase in inflammatory macrophages and the decrease in B cells. Our results provide insight into the effects of Tregs on AT2 cells. Tregs directly or indirectly impact many AT2-cell functions, including IFN type I and II-mediated signaling pathways. Inhibition of IFN-γ expression and/or function may be one mechanism through which Tregs accelerate resolution after acute lung injury.
Indirect interactions among co-infecting parasites and a microbial mutualist impact disease progression
Creators: name: O'Keeffe, Kayleigh R.
name: Mitchell, Charles E.
name: Simha, Anita
Publisher: name: The Royal Society
Year: 2021

description: Interactions among parasites and other microbes within hosts can impact disease progression, yet study of such interactions has been mostly limited to pairwise combinations of microbes. Given the diversity of microbes within hosts, indirect interactions among more than two microbial species may also impact disease. To test this hypothesis, we performed inoculation experiments that investigated interactions among two fungal parasites, Rhizoctonia solani and Colletotrichum cereale, and a systemic fungal endophyte, Epichlo« coenophiala, within the grass, tall fescue (Lolium arundinaceum). Both direct and indirect interactions impacted disease progression. While the endophyte did not directly influence R. solani disease progression or C. cereale symptom development, the endophyte modified the interaction between the two parasites. The magnitude of the facilitative effect of C. cereale on the growth of R. solani tended to be greater when the endophyte was present. Moreover, this interaction modification strongly affected leaf mortality. For plants lacking the endophyte, parasite co-inoculation did not increase leaf mortality compared to single-parasite inoculations. By contrast, for endophyte-infected plants, parasite co-inoculation increased leaf mortality compared to inoculation with R. solani or C. cereale alone by 1.9 or 4.9 times, respectively. Together, these results show that disease progression can be strongly impacted by indirect interactions among microbial symbionts.
Breathing Exercise Application for Enhancing Lung Function Performance in Chronic Obstructive Pulmonary Disease
Creators: name: Sunee Pongpinigpinyo
Publisher: name: KKU Science Journal
Year: 2024
Subjects: Pursed Lip Breathing Technique
Diaphragmatic Breathing Exercises
Borg Scale
Spirometer
Chronic Obstructive Pulmonary Disease (COPD)

description: KKU Science Journal, 52, 2, 135-145
A host immune hormone modifies parasite species interactions and epidemics: insights from a field manipulation
Creators: name: Halliday, Fletcher W.
name: Mitchell, Charles E.
name: Umbanhowar, James
Publisher: name: The Royal Society
Year: 2018

description: Parasite epidemics can depend on priority effects, and parasite priority effects can result from the host immune response to prior infection. Yet we lack experimental evidence that such immune-mediated priority effects influence epidemics. To address this research gap, we manipulated key host immune hormones, then measured the consequences for within-host parasite interactions, and ultimately parasite epidemics in the field. Specifically, we applied plant immune-signalling hormones to sentinel plants, embedded into a wild host population, and tracked foliar infections caused by two common fungal parasites. Within-host individuals, priority effects were altered by the immune-signalling hormone, salicylic acid (SA). Scaling up from within-host interactions, hosts treated with SA experienced a lower prevalence of a less aggressive parasite, increased burden of infection by a more aggressive parasite, and experienced fewer co-infections. Together, these results indicate that by altering within-host priority effects, host immune hormones can drive parasite epidemics. This study therefore experimentally links host immune hormones to within-host priority effects and parasite epidemics, advancing a more mechanistic understanding of how interactions among parasites alter their epidemics.
Supplemental Material - Low energy repair of co-continuous metal-ceramic composites using electrodeposition
Creators: name: Mahmoudi, Mohammadreza
name: Oh, Se
name: Minary-Jolandan, Majid
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental Material for Low energy repair of co-continuous metal-ceramic composites using electrodeposition by Mohammadreza Mahmoudi, Se Oh and Majid Minary-Jolandan in Journal of Composite Materials
Prevalence of lifetime self-injurious thoughts and behaviors in a global sample of 599 patients reporting prospectively confirmed diagnosis with premenstrual dysphoric disorder
Creators: name: Raja, Sabina
name: Wagner-Schuman, Melissa
name: Miller, Adam Bryant
name: Kania, Alyssa
name: Schmalenberger, Katja
name: Buchert, Brett
name: Eisenlohr-Moul, Tory
name: Divine, Madeline
name: Murphy, Laura
name: Barone, Jordan
name: Ross, Jaclyn
Publisher: name: Springer Nature
Year: 2022

description: BackgroundSuicide is the second leading cause of death among Americans ages 10 to 34, with alarming recent increases in suicide rates among those assigned female at birth. A large body of evidence points to menstrual cycle influences on self-injurious thoughts and behaviors (STBs), suggesting that neurobiological hormone sensitivities, such as in premenstrual dysphoric disorder (PMDD), may drive suicide risk in females. However, existing studies of STBs in PMDD use cross-sectional self-report measures of PMDD with poor validity. As a first step to establish accurate prevalence rates of STBs in PMDD, we examined the lifetime prevalence of STBs in a large global survey of patients reporting a diagnosis of PMDD based on daily ratings.MethodIndividuals with self-reported PMDD symptoms were invited to an online survey through online support groups for PMDD and social media posts from PMDD awareness accounts. Participants reported demographics, whether they had been diagnosed with PMDD by a healthcare provider using daily ratings, STBs using the Columbia Suicide Severity Rating Scale, and history of lifetime comorbid psychiatric diagnoses.ResultsOf 2,689 survey completers, 599 (23%) reported a diagnosis with PMDD based on two months of daily ratings and were included in analyses. We observed high rates of lifetime active suicidal ideation (72%), planning (49%), intent (42%), preparing for an attempt (40%), and attempt (34%), as well as non-suicidal self-injury (51%). The majority (70%) of the sample reported at least one lifetime comorbid psychiatric diagnosis. Predictors of lifetime active suicidal ideation included nulliparity, low-to-moderate (vs. high) income, and history of diagnosis with major depression or post-traumatic stress disorder. Predictors of lifetime attempts among those reporting lifetime active ideation included older age, nulliparity, lower income, and history of diagnosis with post-traumatic stress disorder or borderline personality disorder.ConclusionsThese data indicate high rates of STBs among those reporting prospective diagnosis of PMDD and highlight the need for prospective research on mechanisms and prevention of STBs in PMDD. Clinical practice guidelines for PMDD should accommodate comorbidities and recommend frequent screenings for STB risk. STBs should be considered for inclusion in future iterations of the DSM PMDD diagnostic criteria.
sj-pdf-1-acp-10.1177_20578911221144101 - Supplemental material for Voters’ perceptions and evaluations of dynastic politics in Japan
Creators: name: Miwa, Hirofumi
name: Kasuya, Yuko
name: Ono, Yoshikuni
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-pdf-1-acp-10.1177_20578911221144101 for Voters’ perceptions and evaluations of dynastic politics in Japan by Hirofumi Miwa, Yuko Kasuya and Yoshikuni Ono in Asian Journal of Comparative Politics
sj-pdf-1-vmj-10.1177_1358863X221140151 – Supplemental material for Demographic and regional trends of peripheral artery disease mortality in the United States, 2000 to 2019
Creators: name: Issa, Rochell
name: Nazir, Salik
name: Khan Minhas, Abdul Mannan
name: Lang, Jacob
name: Ariss, Robert W
name: Kayani, Waleed Tallat
name: Khalid, Mirza Umair
name: Sperling, Laurence
name: Shapiro, Michael D
name: Jneid, Hani
name: Gupta, Rajesh
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Cardiology
subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-vmj-10.1177_1358863X221140151 for Demographic and regional trends of peripheral artery disease mortality in the United States, 2000 to 2019 by Rochell Issa, Salik Nazir, Abdul Mannan Khan Minhas, Jacob Lang, Robert W Ariss, Waleed Tallat Kayani, Mirza Umair Khalid, Laurence Sperling, Michael D Shapiro, Hani Jneid and Rajesh Gupta in Vascular Medicine
sj-docx-1-aut-10.1177_13623613221143590 – Supplemental material for Development of stigma-related support for autistic adults: Insights from the autism community
Creators: name: Han, Emeline
name: Scior, Katrina
name: Heath, Eric
name: Umagami, Kana
name: Crane, Laura
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: Education
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, sj-docx-1-aut-10.1177_13623613221143590 for Development of stigma-related support for autistic adults: Insights from the autism community by Emeline Han, Katrina Scior, Eric Heath, Kana Umagami and Laura Crane in Autism
Reagent-dictated site selectivity in intermolecular aliphatic C-H functionalizations using nitrogen-centered radicals
Creators: name: Alexanian, Erik J.
name: Carestia, Anthony M.
name: Ravelli, Davide
Publisher: name: Royal Society of Chemistry (RSC)
Year: 2018

description: The site selectivities of intermolecular, aliphatic C-H bond functionalizations are central to the value of these transformations. While the scope of these reactions continues to expand, the site selectivities remain largely dictated by the inherent reactivity of the substrate C-H bonds. Herein, we introduce reagent-dictated site selectivity to intermolecular aliphatic C-H functionalizations using nitrogen-centered amidyl radicals. Simple modifications of the amide lead to high levels of site selectivity in intermolecular C-H functionalizations across a range of simple and complex substrates. DFT calculations demonstrate that the steric demand of the reacting nitrogen-centered radical is heavily affected by the substitution pattern of the starting amide. Optimization of transition state structures consistently indicated higher reagent-dictated steric selectivities using more hindered amides, consistent with experimental results.
Stabilność zawiesiny wodnej łupka miedzionośnego w obecności wody kopalnianej
Creators: name: Michalski, Michał
name: Drzymała, Jan
Publisher: name: Faculty of Geoengineering, Mining and Geology, Wrocław University of Technology, Wrocław
Year: 2017
Subjects: łupek miedzionośny, woda kopalniana

description: Łupek miedzionośny III, Kowalczuk P.B., Drzymała J. (red.), WGGG PWr, Wrocław, ISBN 978-83-946706-0-3
Chemogenetic stimulation of tonic locus coeruleus activity strengthens the default mode network
Creators: name: Shih, Yen-Yu Ian
name: Chao, Tzu-Hao Harry
name: Zhang, Weiting
name: Zhou, Jingheng
name: Smith, Kathleen G
name: Das, Manasmita
name: Jensen, Patricia
name: Hsu, Li-Ming
name: Cui, Guohong
name: Yuan, Hong
name: Song, Sheng
name: Sciolino, Natale R
name: Oyarzabal, Esteban A
name: Lee, Sung-Ho
name: Evsyukova, Irina Y
Publisher: name: American Association for the Advancement of Science (AAAS)
Year: 2022

description: The default mode network (DMN) of the brain is functionally associated with a wide range of behaviors. In this study, we used functional magnetic resonance imaging (fMRI), positron emission tomography (PET), and spectral fiber photometry to investigate the selective neuromodulatory effect of norepinephrine (NE)-releasing noradrenergic neurons in the locus coeruleus (LC) on the mouse DMN. Chemogenetic-induced tonic LC activity decreased cerebral blood volume (CBV) and glucose uptake and increased synchronous low-frequency fMRI activity within the frontal cortices of the DMN. Fiber photometry results corroborated these findings, showing that LC-NE activation induced NE release, enhanced calcium-weighted neuronal spiking, and reduced CBV in the anterior cingulate cortex. These data suggest that LC-NE alters conventional coupling between neuronal activity and CBV in the frontal DMN. We also demonstrated that chemogenetic activation of LC-NE neurons strengthened functional connectivity within the frontal DMN, and this effect was causally mediated by reduced modulatory inputs from retrosplenial and hippocampal regions to the association cortices of the DMN.
Sickle Cell Trait and the Risk of ESRD in Blacks
Creators: name: Judd, Suzanne
name: Naik, Rakhi P
name: Zhi, Degui
name: Winkler, Cheryl A
name: Wilson, James G
name: Cushman, Mary
name: Arnett, Donna
name: Zakai, Neil A
name: Peralta, Carmen
name: Kopp, Jeffrey B
name: Lewis, Michael R
name: Derebail, Vimal K
name: Irvin, Marguerite R
name: McClellan, William
name: Reiner, Alexander P
name: Gutierrez, Orlando M
Publisher: name: Wolters Kluwer
Year: 2017

description: Blacks, compared with whites, have an increased risk of progression to end-stage renal disease (ESRD). Emerging evidence suggests that, in addition to APOL1 high-risk genotypes, hemoglobin variants, including sickle cell trait (SCT) and hemoglobin C trait, have a role in kidney disease in blacks. However, the association between these hemoglobin traits and ESRD remains unknown. In a large population-based cohort, the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, we evaluated 9909 self-reported blacks (739 with SCT and 243 with hemoglobin C trait). Incident ESRD occurred in 40 of 739 (5.4%) individuals with SCT, six of 243 (2.5%) individuals with hemoglobin C trait, and 234 of 8927 (2.6%) noncarriers. The incidence rate for ESRD was 8.5 per 1000 person-years for participants with SCT and 4.0 per 1000 person-years for noncarriers. Compared with individuals without SCT, individuals with SCT had a hazard ratio for ESRD of 2.03 (95% confidence interval, 1.44 to 2.84). Hemoglobin C trait did not associate with prevalent CKD or ESRD. The incidence rate for ESRD among participants with APOL1 high-risk genotypes was 6.6 per 1000 person-years, with a hazard ratio for ESRD of 1.77 (95% confidence interval, 1.31 to 2.38) for participants with, compared with those without, APOL1 high-risk genotypes. In this cohort, SCT strongly associated with risk of progression to ESRD in blacks, and this degree of risk for ESRD was similar to that conferred by APOL1 high-risk genotypes. These results may have important public policy implications for genetic counseling of SCT carriers.
Development of Khanom Arlua Product using Wheat Flour Partially Substituted with Tubtim Chumphae Rice Flour
Creators: name: Montakan Aimkaew
Publisher: name: KKU Science Journal
Year: 2024
Subjects: Khanom Arlua
Tubtim Chumpae Rice
Tubtim Chumpae Rice Flour
Wheat Flour

description: KKU Science Journal, 52, 2, 170-181
Supplemental Material - Evidence of immune response to BNT162b2 COVID-19 vaccine in systemic lupus erythematosus patients treated with Belimumab
Creators: name: Schiavoni, Ilaria
name: Olivetta, Eleonora
name: Natalucci, Francesco
name: Olivieri, Giulio
name: Lo Presti, Alessandra
name: Fedele, Giorgio
name: Stefanelli, Paola
name: Ceccarelli, Fulvia
name: Conti, Fabrizio
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental Material for Evidence of immune response to BNT162b2 COVID-19 vaccine in systemic lupus erythematosus patients treated with Belimumab by Ilaria Schiavoni, Eleonora Olivetta, Francesco Natalucci, Giulio Olivieri, Alessandra Lo Presti, Giorgio Fedele, Paola Stefanelli, Fulvia Ceccarelli and Fabrizio Conti in Lupus
Cation Radical Accelerated Nucleophilic Aromatic Substitution via Organic Photoredox Catalysis
Creators: name: Tay, Nicholas E. S.
name: Nicewicz, David A.
Publisher: name: American Chemical Society (ACS)
Year: 2017

description: Nucleophilic aromatic substitution (SNAr) is a direct method for arene functionalization; however, it can be hampered by low reactivity of arene substrates and their availability. Herein we describe a cation radical-accelerated nucleophilic aromatic substitution using methoxy- and benzyloxy-groups as nucleofuges. In particular, lignin-derived aromatics containing guaiacol and veratrole motifs were competent substrates for functionalization. We also demonstrate an example of site-selective substitutive oxygenation with trifluoroethanol to afford the desired trifluoromethylaryl ether.
Präsent Sein: Achtsamkeit In Der Sozialarbeiterischen Beratung
Creators: name: Oberli-Kohler, Doris
Publisher: name: Zenodo
Year: 2012
Subjects: subject: gnd:4055676-1
subject: gnd:4297929-8
subject: gnd:4047376-4

description: Diese Literaturarbeit befasst sich mit Achtsamkeit in der sozialarbeiterischen Beratung. Die Autorin geht der Frage nach, welche Wirkung Achtsamkeit für Professionelle der Sozialen Arbeit im Beratungskontext zeigen kann. Achtsamkeit ist eine besondere innere Haltung, welche Mitgefühl, Zuwendung und Achtung gegenüber allen Lebensformen beinhaltet. Dadurch, dass sich die ganze Aufmerksamkeit auf das Hier-und-Jetzt richtet, wird eine erhöhte Wachheit und Präsenz erlangt. Bei der Achtsamkeitspraxis geht es indes nicht um eine spontane Aufmerksamkeitsausrichtung, sondern um ein langfristiges Üben zur Verbesserung der Aufmerksamkeitskonstanz und deren Lenkung. Dies bedeutet, dass sich Achtsamkeit nicht allein durch Fachliteratur erarbeiten lässt, sondern nur in Verbindung mit regelmässiger Praxis. Generell zeigt die Achtsamkeitspraxis einen Einfluss auf die Selbstkompetenz von Sozialarbeitenden und kann dazu führen, dass diese ihre eigenen Bedürfnisse und Wünsche differenzierter wahrnehmen. Dies kann sich positiv auf ihre Selbstsorge und das Stressmanagement auswirken, sodass sie auch in hektischen Situationen einen kühlen Kopf bewahren. Wenn ihre Wahrnehmung «verstellt» ist, was sich unter anderem in sogenanntem «Schubladendenken» sowie als Gewohnheit des Beurteilens zeigt, führt dies oftmals zu unreflektierten, reaktiven Handlungen. Die Praxis der Achtsamkeit schult Sozialarbeitende darin, diese Gewohnheiten zu erkennen und bewusst in die Rolle der neutralen Beobachterin respektive des neutralen Beobachters zu schlüpfen. Dies erweitert ihren Handlungsspielraum und stärkt den methodischen Einsatz der «Person als Werkzeug».
description: + Code Diss LU: hslusa basa 2013 + Fussnote: Bachelor-Arbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialarbeit, 2013
Additional file 1 of Perioperative, function, and positive surgical margin in extraperitoneal versus transperitoneal single port robot-assisted radical prostatectomy: a systematic review and meta-analysis
Creators: name: Jiang, Yu
name: Liu, Yang
name: Qin, Shize
name: Zhong, Shuting
name: Huang, Xiaohua
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 1: Table S1. The demographics of the studies.
sj-pdf-5-cep-10.1177_03331024221128250 - Supplemental material for Safety and tolerability results of atogepant for the preventive treatment of episodic migraine from a 40-week, open-label multicenter extension of the phase 3 ADVANCE trial
Creators: name: Klein, Brad C
name: Miceli, Rosa
name: Severt, Lawrence
name: McAllister, Peter
name: Mechtler, Laszlo
name: McVige, Jennifer
name: Diamond, Merle
name: Marmura, Michael J
name: Guo, Hua
name: Finnegan, Michelle
name: Trugman, Joel M
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Endocrinology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-5-cep-10.1177_03331024221128250 for Safety and tolerability results of atogepant for the preventive treatment of episodic migraine from a 40-week, open-label multicenter extension of the phase 3 ADVANCE trial by Brad C Klein, Rosa Miceli, Lawrence Severt, Peter McAllister, Laszlo Mechtler, Jennifer McVige, Merle Diamond, Michael J Marmura, Hua Guo, Michelle Finnegan and Joel M Trugman in Cephalalgia
Thirty-Day Hospital Readmissions in the Hemodialysis Population: A Problem Well Put, But Half-Solved
Creators: name: Assimon, Magdalene M
name: Flythe, Jennifer E
Publisher: name: Wolters Kluwer
Year: 2017

description: In recent years, United States policymakers have made 30-day hospital readmission reduction a centerpiece of efforts to curb Medicare costs. In the general Medicare population, 15% of patients are readmitted to the hospital within 30 days of discharge (1), and unplanned rehospitalizations cost >$20 billion per year (2). In fiscal year 2013, Medicare began levying financial penalties against hospitals with higher than expected readmission rates via the Affordable Care Act’s Hospital Readmissions Reduction Program. The readmission problem is even more dire among individuals receiving maintenance dialysis; 30-day hospital readmission rates are >35% in this vulnerable group (3). To incentivize readmission reduction in the dialysis population, the Centers for Medicare and Medicaid Services implemented the standardized readmission ratio, a pay for performance quality measure for outpatient dialysis clinics, in 2017.
sj-pdf-1-pss-10.1177_09567976221140328 – Supplemental material for Universal Constraints on Linguistic Event Categories: A Cross-Cultural Study of Child Homesign
Creators: name: Rissman, Lilia
name: Horton, Laura
name: Goldin-Meadow, Susan
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-1-pss-10.1177_09567976221140328 for Universal Constraints on Linguistic Event Categories: A Cross-Cultural Study of Child Homesign by Lilia Rissman, Laura Horton and Susan Goldin-Meadow in Psychological Science
66275: Letter: To Marion Scott.
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Written while Ivor Gurney was a patient at the Middlesex War Hospital, where he was sent following numerous suicide threats. Describe surroundings / is glad that recent verses please Marion Scott / promises more to come / mentions 'Crickley Hill' Edward Thomas / includes the poem 'Migrants', which he says is one of his best things / thinks that he may be allowed to play the piano / thanks Scott for some flower that she sent to Warrington / includes 'Twigworth Vicarage' / 'Interval' /a few more to come / a visit to Gloucester Cathedral / reports on books sent as gifts by friends. | File description(s):Envelope containing letter.
Written while Ivor Gurney was a patient at the Middlesex War Hospital, where he was sent following numerous suicide threats. Describe surroundings / is glad that recent verses please Marion Scott / promises more to come / mentions 'Crickley Hill' Edward Thomas / includes the poem 'Migrants', which he says is one of his best things / thinks that he may be allowed to play the piano / thanks Scott for some flower that she sent to Warrington / includes 'Twigworth Vicarage' / 'Interval' /a few more to come / a visit to Gloucester Cathedral / reports on books sent as gifts by friends.
แนวทางการพัฒนาการออกแบบชุมชนเมืองด้วยการเติมเต็มบทบาททางวิชาชีพ
Creators: name: วิมลสิทธิ์ หรยางกูร
Publisher: name: Thammasat Printing House
Year: 2017
Subjects: การออกแบบชุมชนเมือง
การเปลี่ยนแปลงสู่ความเป็นเมือง
ความน่าอยู่อาศัย
บทบาททางวิชาชีพ

description: Journal of Architectural/Planning Research and Studies, 14, 2, 1.-14
sj-doc-1-acr-10.1177_02841851221138519 - Supplemental material for Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population
Creators: name: Renard, Anne-Sophie
name: Paisant, Anita
name: Cartier, Victoire
name: Calès, Paul
name: Goyet-Prelipcean, Mirela
name: Geagea, Edmond
name: Tasu, Jean-Pierre
name: Silvain, Christine
name: Wagner, Mathilde
name: Cleach, Aline Le
name: Vilgrain, Valérie
name: Castera, Laurent
name: Bricault, Ivan
name: Decaens, Thomas
name: Savoye-Collet, Céline
name: Montialoux, Hélène
name: Correas, Jean-Michel
name: Vallet-Pichard, Anaïs
name: Boursier, Jérôme
name: Aubé, Christophe
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110320 Radiology and Organ Imaging
subject: FOS: Clinical medicine

description: Supplemental material, sj-doc-1-acr-10.1177_02841851221138519 for Validation of a screening algorithm for hepatic fibrosis by Doppler ultrasound and elastography in a general population by Anne-Sophie Renard, Anita Paisant, Victoire Cartier, Paul Calès, Mirela Goyet-Prelipcean, Edmond Geagea, Jean-Pierre Tasu, Christine Silvain, Mathilde Wagner, Aline Le Cleach, Valérie Vilgrain, Laurent Castera, Ivan Bricault, Thomas Decaens, Céline Savoye-Collet, Hélène Montialoux, Jean-Michel Correas, Anaïs Vallet-Pichard, Jérôme Boursier and Christophe Aubé in Acta Radiologica
Toward Patient-Centered Innovation: A Conceptual Framework for Patient-Reported Outcome Measures for Transformative Kidney Replacement Devices
Creators: name: Flythe, Jennifer E
name: West, Melissa
name: Unruh, Mark
name: Keller, San
name: Hurst, Frank P
name: Ikeler, Kourtney
name: Perrone, Ronald D
name: Gipson, Debbie S
name: Nordyke, Robert J
name: W.G.
name: Grandinetti, Amanda C
name: Hilliard, Tandrea S
name: Bocell, Fraser
name: Roy-Chaudhury, Prabir
Publisher: name: Wolters Kluwer
Year: 2020

description: Individuals with dialysis-dependent kidney failure experience considerable disease- and treatment-related decline in functional status and overall well-being. Despite these experiences, there have been few substantive technological advances in KRT in decades. As such, new federal initiatives seek to accelerate innovation. Historically, integration of patient perspectives into KRT product development has been limited. However, the US Food and Drug Administration recognizes the importance of incorporating patient perspectives into the total product life cycle (i.e., from product conception to postmarket surveillance) and encourages the consideration of patient-reported outcomes in regulatory-focused clinical trials when appropriate. Recognizing the significance of identifying patient-reported outcome measures (PROMs) that capture contemporary patient priorities, the Kidney Health Initiative, a public-private partnership between the American Society of Nephrology and US Food and Drug Administration, convened a workgroup to (1) develop a conceptual framework for a health-related quality of life PROM; (2) identify and map existing PROMs to the conceptual framework, prioritizing them on the basis of their supporting evidence for use in the regulatory environment; and (3) describe next steps for identifying PROMs for use in regulatory clinical trials of transformative KRT devices. This paper summarizes the proposed health-related quality-of-life PROM conceptual framework, maps and prioritizes PROMs, and identifies gaps and future needs to advance the development of rigorous, meaningful PROMS for use in clinical trials of transformative KRT devices.
Additional file 2 of Perioperative, function, and positive surgical margin in extraperitoneal versus transperitoneal single port robot-assisted radical prostatectomy: a systematic review and meta-analysis
Creators: name: Jiang, Yu
name: Liu, Yang
name: Qin, Shize
name: Zhong, Shuting
name: Huang, Xiaohua
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 2. The potential origins of heterogeneity appear to stem from disparities in publication year and the variations in the size.
Turning the Tide: Improving Fluid Management in Dialysis through Technology
Creators: name: Flythe, Jennifer E
Publisher: name: Wolters Kluwer
Year: 2017

description: Over the last decade, components of fluid management have emerged as some of the most important modifiable risk factors for morbidity and mortality among individuals on maintenance dialysis. Hypervolemia, either chronic from long-term volume overload or episodic from large interdialytic weight gains, may increase the risk of left ventricular hypertrophy and its adverse downstream cardiovascular consequences. Conversely, hypovolemia from either too voluminous or too rapid of fluid removal may lead to multiorgan ischemia and associated clinical sequelae.3,4 Experts recognize the need for balance between the extremes of volume status and ultrafiltration, but inter-relationships among volume-related components, lack of data on their relative importance, and absence of relevant clinical trials hinder consensus guideline development. Notwithstanding the paucity of trial evidence in this arena, international experts and United States dialysis organization leaders concur that putting “volume first” is essential if the dialysis community is to successfully “turn the tide” on the unacceptably poor outcomes experienced by our patients.
sj-docx-1-jdr-10.1177_00220345221138569 – Supplemental material for Sweet Taste Receptor Gene and Caries Trajectory in the Life Course
Creators: name: Chisini, L.A.
name: Costa, F.D.S.
name: Horta, B.L.
name: Tovo-Rodrigues, L.
name: Demarco, F.F.
name: Correa, M.B.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-docx-1-jdr-10.1177_00220345221138569 for Sweet Taste Receptor Gene and Caries Trajectory in the Life Course by L.A. Chisini, F.D.S. Costa, B.L. Horta, L. Tovo-Rodrigues, F.F. Demarco and M.B. Correa in Journal of Dental Research
Targeting the NO/sGC/cGMP signaling pathway in health and disease
Creators: name: Ravi, Ravina Maru
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: The therapeutic utility of the nitric oxide (NO)/soluble guanylyl cyclase (sGC)/cyclic guanosine 3’5’-monophosphate (cGMP) pathway is well-recognised, with NO donors used in the treatment of diseases such as heart failure, acute hypertensive crisis and pulmonary hypertension. However, traditional nitrovasodilator therapy is somewhat limited due to the development of tolerance following prolonged administration. Furthermore, in vascular disease states such as hypertension, the NO/sGC/cGMP pathway appears to be dysfunctional. Such dysfunction is thought to arise as a consequence of oxidative stress and the associated increase in vascular superoxide anion radical (•O2-) levels, leading to enhanced scavenging of NO to form the oxidant, peroxynitrite (ONOO-). Indeed, ONOO- is able to oxidise the reduced (Fe2+) heme group of sGC, converting it into its NO-insensitive ferric (Fe3+) or heme-free forms. Under such conditions, the efficacy of NO donors/nitrovasodilators are compromised, due to their inability to target these altered states of sGC, underlining the need for novel non-NO based compounds. As such, this thesis examines the vaso-protective actions and therapeutic potential of the redox sibling of NO, nitroxyl (HNO), as well as NO-independent sGC stimulators (BAY 41-2272) and activators (BAY 58-2667) in a number of cardiovascular disease states. From a clinical perspective, NO-independent compounds such as HNO donors and/or stimulators and activators of sGC may offer considerable therapeutic advantages over traditional nitrovasodilator therapies due to their well-documented resistance to •O2- scavenging and vascular tolerance development, as well as the ability to target oxidised/heme-free sGC (i.e. BAY 58-2667) and the potential to mediate their effects via cGMP-independent mechanisms of action. Such compounds may also offer the basis from which future therapies, for the treatment of cardiovascular diseases, are designed.