cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Downregulation of Sirt1 is correlated to upregulation of p53 and increased apoptosis in epicardial adipose tissue of patients with coronary artery disease
Creators: name: Khanahmadi, Mahdieh
name: Manafi, Babak
name: Tayebinia, Heidar
name: Karimi, Jamshid
name: Khodadadi, Iraj
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2020
Subjects: subject: Apoptosis
subject: Atherosclerosis
subject: Coronary artery disease
subject: Epicardial adipose tissue
subject: Sirt1
subject: p53
subject: 610

description: The higher expression level of p53 in epithelial adipose tissue (EAT) has previously been reported in atherosclerosis. Since we hypothesized that the expression of p53 is modulated by Sirt1, the aim of this study was to determine the expression levels of Sirt1 and p53 and to investigate their correlation to apoptosis in EAT of patients with coronary artery disease (CAD). Thirty-five patients with more than 50 % stenosis in at least one of the main coronary arteries were considered as CAD group while 29 patients with no clinical signs of atherosclerosis who underwent open-heart surgery for valve replacement were classified as control group. EAT biopsy samples were collected from all participants during surgery. Sirt1, p53, Bax, and Bcl‑2 gene expression levels were determined in EAT by qRT-PCR and Western blotting was carried out to assess Sirt1 and p53 protein levels. Hematoxylin and eosin staining was used for histopathological analysis. mRNA and protein levels of Sirt1 in EAT were significantly lower in patients with CAD compared with control group, whereas CAD patients showed greater p53 gene and protein expressions. In addition, inverse correlations were observed between Sirt1 and p53 at both mRNA and protein levels. The Bax and ratio of Bax/Bcl-2 gene expressions were higher in CAD group, but no difference was observed in Bcl-2 expression. Histopathological analysis showed apoptotic bodies and infiltrated immune cells in EAT of CAD group. Our results suggest that the Sirt1-p53 axis may involve in atherosclerosis by promotion of apoptosis.
description: EXCLI Journal;Vol. 19 2020
Real-Time Queue Length Estimation Using Probe Vehicles with Cumulative Input-Output Technique
Creators: name: Islam, Md Kamrul
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Engineering--Civil
subject: Queue
subject: Traffic
subject: Real-time

description: Real-time vehicular queue length is an important parameter describing the temporal and spatial state of a traffic stream. A queue is the direct outcome of bottlenecks or roadway congestion, which causes longer travel times and delays and adversely impacts roadway performance. Therefore, in this thesis, two congestion scenarios, namely two roadway bottleneck cases (bottleneck over a roadway lane due to a merging lane/ramp and bottleneck due to a lane closure induced by an incident) and two signalized intersection cases (undersaturated and oversaturated) have been investigated to estimate the back of queue. The proposed methodology for real-time queue estimation is based on a GPS-based probe-vehicle trajectory data analysis obtained from a Paramics simulation environment applied in combination with an input-output technique. An extension of the queue estimation method of Lawson, Lovell and Daganzo (1996), based on a more realistic fundamental diagram of traffic flow, has also been proposed for bottleneck situations. Although the proposed methodologies maintain some strict assumptions, it has been found that the probe-based proposed methodology with a probe market share of around 30 percent is enough to outperform the theoretical Lawson et al. queue estimation model for all the case studies. Last, but not the least, this thesis should be considered as the first known contribution that focuses on the input-output technique and probe-vehicle information in the estimation of a real-time vehicular queue.
Panulirus laevicauda Latreille 1817
Creators: name: Almeida, Alexandre Oliveira De
name: Guerrazzi, Maria Cec Lia
name: Coelho, Petr Ȏ Nio Alves
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Palinuridae
Panulirus
Panulirus laevicauda

description: Panulirus laevicauda (Latreille, 1817)
Material examined (N=1). 1f, 18/IX/2000, 13°52’37”S / 38°57’11”W (MZUESC #55).
Distribution. Western Atlantic – Bermuda, Florida, Gulf of Mexico, Central America, Antilles, northern South America, Guyanas, and Brazil (Fernando de Noronha, and from Maranhão to São Paulo) (Coelho & Ramos-Porto 1980; Coelho & Ramos-Porto 1998b).
Ecological notes. On reefs, rocks, and calcareous algae bottoms. From shallow waters to 50 m (Melo 1999).
Previous records in Bahia. Almeida et al. (2007).
description: Published as part of Almeida, Alexandre Oliveira De, Guerrazzi, Maria Cec Lia & Coelho, Petr Ȏ Nio Alves, 2007, Stomatopod and decapod crustaceans from Camamu Bay, state of Bahia, Brazil, pp. 1-45 in Zootaxa 1553 on page 22, DOI: 10.5281/zenodo.178168
BALANCING ACT: NAVIGATING THE COVID-19 CRISIS IN ECONOMICALLY DISTRESSED COMMUNITIES
Creators: name: Sarah, Maguire, Ph.D
name: James, Dr. Oduor, Ph.D
name: Anderson, Dr. Emily
Publisher: name: Zap journals
Year: 2023
Subjects: COVID-19, pandemic,
SARS-CoV-2
global response
containment measures

description: In early 2020, a novel flu-like illness, later named Coronavirus Disease (COVID-19), emerged and began to spread globally. It posed a significant threat to the elderly and those with underlying health conditions, leading governments worldwide to implement various containment measures. These measures ranged from restricting air travel to imposing lockdowns, with Italy becoming an epicenter for the virus in March 2020. The rapid and asymmetrical transmission of the virus raised concerns, making nursing homes and cruise ships particularly vulnerable to outbreaks.
The World Health Organization and global health experts identified the illness as a severe acute respiratory syndrome caused by the novel virus, SARS-CoV-2. This virus could be transmitted in aerosolized form and had a wide incubation period. Understanding the dynamics of the COVID-19 pandemic and its impact on different regions and demographics became crucial for public health responses.
Interleukin-6 is associated with tryptophan metabolism and signs of depression in individuals with carbohydrate malabsorption
Creators: name: Enko, Dietmar
name: Zelzer, Sieglinde
name: Wenninger, Julian
name: Holasek, Sandra
name: Schnedl, Wolfgang J.
name: Baranyi, Andreas
name: Herrmann, Markus
name: Meinitzer, Andreas
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2020
Subjects: subject: Depression
subject: Inflammation
subject: Interleukin-6
subject: Interferon-gamma
subject: Tumor necrosis factor-alpha
subject: Lactoferrin
subject: 610

description: The aim of the present study was to investigate possible associations between interleukin-6 (IL-6), interferon-gamma (INF-γ), tumor necrosis factor-alpha (TNF-α), lactoferrin and lipopolysaccharide binding protein (LBP) with TRP metabolism and signs of depression in a large cohort of outpatients referred for carbohydrate malabsorption testing. Serum concentrations of IL-6, INF-γ, TNF-α, lactoferrin, LBP, tryptophan (TRP), kynurenine (KYN) and kynuric acid were determined in 250 adults referred for lactose and fructose malabsorption testing. All participants filled out the Beck Depression Inventory (BDI). Serum IL-6 levels were positively correlated with the BDI score (p = 0.001, ρ = 0.205) and indicators of TRP metabolism (KYN/TRP ratio, KYN) (P-values < 0.05, ρ = 0.176 and 0.136). Ninety-five individuals with a BDI score > 13 showed significantly higher IL-6 serum levels (1.7 [1.0 – 2.8] vs. 1.1 [0.8 – 1.7] pg/mL, p < 0.001) compared to 115 individuals with a BDI score ≤ 13. LBP showed a positive correlation with the KYN/TRP ratio (p = 0.005, ρ = 0.177). IL-6 and LBP were associated with indicators of TRP metabolism. IL-6 was found to be linked to signs of depression. Individuals with the presence of depressive symptoms showed higher serum IL-6 levels compared to individuals without depressive symptoms.
description: EXCLI Journal;Vol. 19 2020
Spectroscopic mapping of local structural distortions in ferroelectric PbTiO3/SrTiO3 superlattices at the unit-cell scale
Creators: name: Torres-Pardo, Almudena
name: Gloter, Alexandre
name: Zubko, Pavlo
name: Jecklin, Noemie
name: Lichtensteiger, Celine
name: Colliex, Christian
name: Triscone, Jean-Marc
name: Stephan, Odile
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The local structural distortions in polydomain ferroelectric PbTiO3/SrTiO3 superlattices are investigated by means of high spatial and energy resolution electron energy loss spectroscopy combined with high angle annular dark field imaging. Local structural variations across the interfaces have been identified with unit cell resolution through the analysis of the energy loss near edge structure of the Ti-L2,3 and O-K edges. Ab-initio and multiplet calculations of the Ti-L2,3 edges provide unambiguous evidence for an inhomogeneous polarization profile associated with the observed structural distortions across the superlattice.
description: 5 pages, 4 figures
Overexpression and translocation of dynamin 2 promotes tumor aggressiveness in breast carcinomas
Creators: name: Sajed, Roya
name: Saeednejad Zanjani, Leili
name: Rahimi, Mandana
name: Mansoori, Maryam
name: Zarnani, Amir-Hassan
name: Madjd, Zahra
name: Ghods, Roya
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2020
Subjects: subject: Dynamin 2
subject: Breast cancer
subject: Immunohistochemistry
subject: Tissue microarray (TMA)
subject: Invasion
subject: Cancer progression
subject: 610

description: Dynamin 2 is a GTPase protein that has been implicated in cancer progression through its various roles such as endocytosis, morphogenesis, epithelial-mesenchymal transition (EMT), cellular contractions, and focal adhesion maturation. The increased expression levels of this molecule have been demonstrated with the development of several cancers such as prostate, pancreas, and bladder. However, its clinical significance in breast cancer is unclear yet. In the present study, the membranous, cytoplasmic, and nuclear expression levels of dynamin 2 molecule were evaluated for the first time, using immunohistochemistry (IHC) on tissue microarray (TMA) slides in 113 invasive breast cancer tissues. Moreover, afterward, the association between the dynamin 2 expression and clinicopathological features was determined. Our finding showed that, a higher nuclear expression of dynamin 2 is significantly associated with an increase in tumor stage (P = 0.05), histological grade (P = 0.001), and age of the patients (P = 0.03). In addition, analysis of the cytoplasmic expression levels of this molecule revealed that, there was a statistically significant difference between the expression levels of dynamin 2 among the different breast cancer subtypes (P = 0.003). Moreover, a significant association was found between the increased expression of dynamin 2 membranous and vascular invasion (VI) (P = 0.02). We showed that dynamin 2 protein expression has an association with more aggressive tumor behavior and more advanced disease in the patients with breast cancer; therefore, dynamin 2 molecule could be considered as an indicator of disease progression and aggressiveness.
description: EXCLI Journal;Vol. 19 2020
Revealing the astragalin mode of anticandidal action
Creators: name: Ivanov, Marija
name: Kannan, Abhilash
name: Stojkovic, Dejan
name: Glamočlija, Jasmina
name: Golič Grdadolnik, Simona
name: Sanglard, Dominique
name: Soković, Marina
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2020
Subjects: subject: Astragalin
subject: Mode of action
subject: Antimicrobial
subject: Ergosterol biosynthesis
subject: Hyphal transition
subject: Membrane integrity
subject: 610

description: Due to limited arsenal of systemically available antifungal agents, infections caused by Candida albicans are difficult to treat and the emergence of drug-resistant strains present a major challenge to the clinicians worldwide. Hence further exploration of potential novel and effective antifungal drugs is required. In this study we have explored the potential of a flavonoid, astragalin, in controlling the growth of C. albicans, in both planktonic and biofilm forms by microdilution method; and in regulating the morphological switch between yeast and hyphal growth. Astragalin ability to interfere with membrane integrity, ergosterol synthesis and its role in the regulation of genes encoding for efflux pumps has been addressed. In our study, astragalin treatment produced good antimicrobial and significant antibiofilm activity. Anticandidal activity of astragalin was not related to ERG11 downregulation, neither to direct binding to CYP51 enzyme nor was linked to membrane ergosterol assembly. Instead, astragalin treatment resulted in reduced expression of CDR1 and also affected cell membrane integrity without causing cytotoxic effect on human gingival fibroblast cells. Considering that astragalin-mediated decreased expression of efflux pumps increases the concentration of antifungal drug inside the fungal cells, a combinatorial treatment with this agent could be explored as a novel therapeutic option for candidiasis.
description: EXCLI Journal;Vol. 19 2020
Optical Quantum Memory and Signal Processing Using a Rare-earth-ion-doped Waveguide
Creators: name: Sinclair, Neil
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Physics--Atomic
subject: Optics
subject: Quantum Memory
subject: Quantum Repeaters
subject: Quantum Signal Processing
subject: Rare-earth-ion-doped Crystals

description: Advanced applications of quantum information science, such as long-distance quantum communication based on quantum repeaters, require photons to be interfaced with different devices. These devices, such as single photon detectors, quantum memories, quantum signal processors, and linear optical elements, may be integrated on a single chip to enable efficient, robust and scalable implementations. With aim of constructing a quantum repeater, and towards realizing integrated optical quantum memories and signal processors in general, we experimentally develop quantum light-matter interfaces using a cryogenically-cooled rare-earth-ion-doped waveguide, namely thulium-doped lithium niobate (Tm3+:LiNbO3). As the basis for our work, we describe a quantum repeater architecture that uses spectral multiplexing and quantum memories that operate with a fixed storage time. Our repeater architecture promises efficient operation, is compatible with the properties of cryogenically-cooled rare-earth-ion-doped crystals, and simplifies the demands of quantum memories compared to other architectures. To demonstrate the feasibility of our repeater design, we utilize our light-matter interface as a quantum memory to perform several experimental demonstrations. These include high-fidelity storage and retrieval of 26 spectrally-multiplexed quantum bits encoded into single-photon-level laser pulses, high-fidelity storage and retrieval of single and entangled photons derived from a photon-pair source, and high-visibility two-photon interference between weak laser pulses that are stored in one or two, separate, quantum memories. The unique properties of our light-matter interface allow us to demonstrate additional protocols that further highlight its promise for integrated quantum signal processing. By combining our Tm3+:LiNbO3 waveguide with a LiNbO3 waveguide phase modulator, we demonstrate operations such as sequencing, filtering, interference, and compression of laser pulses attenuated to the single-photon level. In another experiment, we measure the cross-phase modulation between strong pulses, by which we demonstrate photon-photon interactions that point towards non-destructive measurements of quantum bits. Since the performance of all aforementioned protocols, and future light-matter applications, hinge on the basic spectroscopic properties of our waveguide, we measure these properties at temperatures as low as 800 millikelvin. Our findings, discussed over several attached publications, usher the development of integrated quantum memories and processors for multi-component optical quantum information applications such as repeaters and networks.
Re-entry and transition factors for returning Canadian Forces military members from overseas deployments
Creators: name: Sorsdahl, Michael Neil
Publisher: name: University of British Columbia
Year: 2010

description: This study investigated the factors that affect the re-entry process of military members returning from overseas deployments, using the Critical Incident Technique method. To date, no other study has adequately investigated to this degree and focus, looking at what factors helped and hindered the successful reintegration process. This study expands the understanding of what is desired by military members on return from overseas deployments. It also presents an adaptation of a new theoretical model of re-entry. Fifteen participants were selected through their response to a ‘call for volunteers’ letter sent to military personnel in the vicinity who were either known by the researcher, known through the Veterans Transition Program coordinated by Dr. Marv Westwood, or known through those solicited persons above to have returned from overseas deployment over a year ago. The incident categories were rated by thirteen of the fifteen study participants as well as two external persons (one with military background and the other with no military background). The ratings of the categories resulted in over 90% concurrence through placing a random selection of incidents into the investigator-created categories. A total of 445 critical incidents were gathered, with 5 categories that helped the re-entry process, and 6 categories that hindered the re-entry process. The findings of this study are consistent with previous literature pertaining to military members who have returned from deployments, but also expand the information discussed in the literature. The unique findings of this study propose changes to the current programs available to military members and a adapted model of re-entry for military members. These new programs include adaptations to the military decompression program, the use of group therapy composed of other military members, the essential need to talk to others as an instrumental component of successful reintegration, and also an adapted model of re-entry for military members is proposed.
Noise-Immune Digital Circuit Design Based on Probabilistic Models
Creators: name: Tangim, Golam
Publisher: name: Graduate Studies
Year: 2012
Subjects: subject: Engineering--Electronics and Electrical
subject: Probabilistic Computing
subject: Markov Random FIeld
subject: Binary Decision Diagram

description: This thesis focuses on the logic design architectures that are inherently tolerant to noise. It aims at achieving noise-tolerance using Markov Random Field (MRF). This model considers inputs and outputs of a circuit as random variables and the function is evaluated via correct network states, which maximize the joint probability distribution of those variables. In implementation, this translates in creating a feedback that reinforces the correct states. Such circuits are simulated using the 16nm predictive CMOS technology model in SPICE. This thesis proposes the implementation of MRF using Binary decision Diagrams (BDDs) where such circuits are realized on bi-directional switches. To accomplish the stability, we introduce BDD with feedback, called Cyclic BDD. The proposed designs are oriented at hardware implementation on the BDD based wrap-gate nanowire architectures. The comparison of the proposed design against conventional probabilistic models, in terms of performance, shows lesser power dissipation with the minimum area overhead.
Compare forced- with free-response method on studying interference-control in the general population
Creators: name: Jonides, John
name: Wang, Su
name: Scroppo, Noah
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Cognitive Psychology
subject: Psychology
subject: FOS: Psychology
subject: Social and Behavioral Sciences
subject: Cognition and Perception

description: This is a three-session study. The data are collected from Prolific. In the first two sessions, each participant will do the same nonverbal interference tasks, either the Flanker task, or the Simon task. However, one of the two sessions has the forced timing request for the participants, called “forced-response”, and the other one is called “free-response”. The aim of the first two sessions is to compare the forced-response method and the free-response method in studying interference-control in the general population and to investigate whether we can use model parameters from different tasks to form a latent variable to predict self-reported ADHD symptoms according to an ASRS survey following the free-response task. In order to counterbalance the participants, the order of the two sessions is randomly chosen for each participant on Prolific. Both sessions have 6 test blocks from which we collected the data, and each block contains 70 trials, with 10 dummy trials at the beginning. However, the third session has a separate goal that is more exploratory. Thus, this pre-registration criteria document is only for the first two sessions. We will use Python to perform the data pre-registration. And the order will start with a block-level, then a subject-level, and finally a trial-level data cleaning. If a participant is excluded from the data analysis because of weak performance in one session, his/her data for the other two sessions should also not be used.
Limiting absorption principle and perfectly matched layer method for Dirichlet Laplacians in quasi-cylindrical domains
Creators: name: Kalvin, Victor
Publisher: name: arXiv
Year: 2011
Subjects: subject: Analysis of PDEs (math.AP)
subject: Numerical Analysis (math.NA)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics

description: We establish a limiting absorption principle for Dirichlet Laplacians in quasi-cylindrical domains. Outside a bounded set these domains can be transformed onto a semi-cylinder by suitable diffeomorphisms. Dirichlet Laplacians model quantum or acoustically-soft waveguides associated with quasi-cylindrical domains. We construct a uniquely solvable problem with perfectly matched layers of finite length. We prove that solutions of the latter problem approximate outgoing or incoming solutions with an error that exponentially tends to zero as the length of layers tends to infinity. Outgoing and incoming solutions are characterized by means of the limiting absorption principle.
description: to appear in SIAM Journal on Mathematical Analysis
title: ELEMENTARY SCHOOL CHILDREN’S UNDERSTANDING OF DISPROPORTIONATE DISCIPLINE
Creators: name: Biefeld, Sharla
Publisher: name: University of Kentucky Libraries
Year: 2020
Subjects: subject: FOS: Educational sciences

description: In the U.S. Black students, particularly Black boys, receive more out of school punishments, are punished more frequently, and are punished for more subjective behaviors than their White peers (Skiba, Michael, Nardo, & Peterson, 2002). This phenomenon is referred to as disproportionate discipline and is an early precursor to the disproportionate number of Black men and boys incarcerated in the U.S. Disproportionate discipline begins as early as preschool, and continues throughout elementary, middle, and high school (Gregory & Fergus, 2017). Perceptions of discrimination greatly impact children’s school involvement, school belonging, and educational outcomes (Brown, 2017, for review). However, little is known about elementary children’s perceptions of discriminatory discipline practices. In the current study, I investigated elementary school children’s (6-11 years old; Mage = 7.75; SD = 1.31) perceptions of disproportionate discipline, utilizing a mixed method approach. Participants (n = 63; 63.5% White, 6.3% Latinx, 9.5% Black; 6.3% Asian, and 14.4% preferred to self-describe) were shown four vignettes describing different misbehavior of a White or Black child and a teacher punishing them. Results suggest that children in middle childhood perceive disproportionate discipline as discrimination. Qualitative analyses also suggest that Black children are more likely to be perceived as culpable for their misbehavior and less likely to be perceived as accidentally misbehaving compared to White children. Children’s cognitive development also informed their perceptions of teacher discrimination. Important implications for these findings are also discussed.
description: © 2020 Sharla D. Biefeld
Next-Generation Sequencing of vlsE Recombinational Switching in the Lyme Spirochete
Creators: name: Verhey, Theodore
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biology--Molecular
subject: Antigenic Variation
subject: Molecular Evolution
subject: Gene Conversion
subject: Immune Evasion
subject: Borrelia burgdorferi
subject: Lyme disease

description: Borrelia burgdorferi and other spirochetes that cause Lyme disease effectively evade the acquired immune response through antigenic variation. The VlsE antigen is expressed on the spirochete surface during mammalian infection. Virtually unlimited numbers of variants are generated through segmental gene conversion events at the vlsE gene from a series of nearby silent cassette sequences that are homologous to the variable region of vlsE. In contrast to other antigenic variation systems, the molecular mechanism for this switching is unknown. Switching at vlsE is dependent on mammalian host factors and the only known requirement is the RuvAB branch migrase; RecA and many of the other homologous recombination proteins in B. burgdorferi are not required. In this study, we developed a new assay for switching at vlsE based on PacBio sequencing and an analytical pipeline that allows the analysis of tens of thousands of full-length variants. We developed the first fully-automated and unbiased method to accurately identify switch events and non-templated mutations from sequence data. This software also contains a large suite of dataset management and analysis tools to quantify many aspects of switch events and the switching process in the dataset. Following a time-course of B. burgdorferi infection in immunocompetent and immunocompromised mice in a variety of tissues, we uncover a series of new insights into recombinational switching at vlsE. We demonstrate that although switching requires mammalian host factors, the rate of vlsE switching is unaffected by the presence or absence of the required immune system. We identify residues that undergo diversifying and stabilizing selection in the VlsE protein in the presence of acquired immunity. We also report accurate rates of recombination and nontemplated mutation, the size and origin of switch events, a role for local sequence homology in promoting switching, and that switch events accumulate in a clustered rather than uniform fashion. We also quantify a secondary mechanism of sequence variation by demonstrating that polymerase slippage generates in-frame, surface-localized insertions and deletions that contribute to VlsE variability.
The multi-identities of Canadian high school students of South Asian heritage
Creators: name: Binning, Priya
Publisher: name: University of British Columbia
Year: 2010

description: This study examined the notions of culture and identity held by high school students, of mainly Punjabi descent, in a Punjabi 11 class as realized through their completion of a unit designed to allow them to learn about themselves and their attitudes and beliefs regarding what comprised their culture. Data was collected through a unit of study created to allow the students to explore their identities and included student journals, reflections and final projects and presentations. The findings suggest that while the students identified themselves as Canadian, a Canadian identity often appeared to be second to their ethnic or religious identity (such as being Punjabi or Sikh). What came to the forefront is that Punjabi students see themselves as having a unique cultural identity that they share with other students of similar backgrounds. For many, this essential group identity creates the foundation for their social networks. Two of the main factors that create this group identity appear to be religion and culture, both of which are taught at home by the family, supported by Punjabi media and validated by their friends at school. The expectations placed upon the participants by family are accepted and not often questioned and are instead considered to be duties that need to be fulfilled. Moreover, religion and culture are terms that appear, for some, to be interchangeable for many of the participants in this study and this does not pose a problem for them or their identities. There are also elements of being Punjabi and being Canadian that could be interpreted as being conflictual but are not perceived as such by the students, such as wanting to maintain traditional gender roles and marriage practices while also embracing the independence and freedom to choose your own path that comes with being Canadian. This study contributes to our understanding of adolescent Indo-Canadians by exploring what their notions of identity are and how they see themselves, within their social groups, school community and at home. Future research should be focused on a larger, more diverse population of Indo-Canadian teenagers to concretely substantiate the ideas presented in this study.
A conformal integral invariant on Riemannian foliations
Creators: name: Wang, Guofang
name: Zhang, Yongbing
Publisher: name: arXiv
Year: 2011
Subjects: subject: Differential Geometry (math.DG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: Let $M$ be a closed manifold which admits a foliation structure $\mathcal{F}$ of codimension $q\geq 2$ and a bundle-like metric $g_0$. Let $[g_0]_B$ be the space of bundle-like metrics which differ from $g_0$ only along the horizontal directions by a multiple of a positive basic function. Assume $Y$ is a transverse conformal vector field and the mean curvature of the leaves of $(M,\mathcal{F},g_0)$ vanishes. We show that the integral $\int_MY(R^T_{g^T})dμ_g$ is independent of the choice of $g\in [g_0]_B$, where $g^T$ is the transverse metric induced by $g$ and $R^T$ is the transverse scalar curvature. Moreover if $q\geq 3$, we have $\int_MY(R^T_{g^T})dμ_g=0$ for any $g\in [g_0]_B$. However there exist codimension 2 minimal Riemannian foliations $(M,\mathcal{F},g)$ and transverse conformal vector fields $Y$ such that $\int_MY(R^T_{g^T})dμ_g\neq 0$. Therefore, it is a nontrivial obstruction for the transverse Yamabe problem on minimal Riemannian foliation of codimension 2.
description: 10 pages
Flowing Funnels: Heat sources for field theories and the AdS_3 dual of CFT_2 Hawking radiation
Creators: name: Fischetti, Sebastian
name: Marolf, Donald
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We construct the general 2+1 dimensional asymptotically AdS_3 solution dual to a stationary 1+1 CFT state on a black hole background. These states involve heat transport by the CFT between the 1+1 black hole and infinity (or between two 1+1 black holes), and so describe the AdS dual of CFT Hawking radiation. Although the CFT stress tensor is typically singular at the past horizon of the 1+1 black hole, the bulk 2+1-dimensional solutions are everywhere smooth, and in fact are diffeomorphic to AdS_3. In particular, we find that Unruh states of the CFT on any finite-temperature 1+1 black hole background are described by extreme horizons in the bulk.
description: 24 pages
Vengeful Decisions: The Role of Perceived Effectiveness and Costliness of Revenge
Creators: name: Rasmussen, Kyler
Publisher: name: Arts
Year: 2013
Subjects: subject: Social
subject: revenge
subject: perceived consequences
subject: justice

description: Conventional wisdom suggests that individuals who decide to get even are driven by their emotions and cannot be swayed by considering the potential consequences of their actions. If this is the case, then perceptions of revenge’s consequences—its effectiveness and costliness—should be unrelated to the likelihood of taking revenge. The present study examined the relationships between these variables among 199 undergraduates. We had participants imagine that their romantic partners had cheated on them, and asked them to list the consequences, both positive and negative, of getting even, along with their perceptions of how effective and how costly revenge would be. We also asked participants to rate their endorsement of particular goals following a provocation. Ratings of revenge’s effectiveness are largely related to the positive consequences of getting even, while ratings of revenge’s costliness are largely related to revenge’s negative consequences. Goal endorsement is related to perceiving some potential responses to a provocation as more effective than others. Judgments of effectiveness and costliness predicted significant variance in the likelihood of engaging in revenge (R2 = .59) suggesting that perceptions of effectiveness and costliness may play a more important role in revenge decision making than previously thought. A significant Effectiveness X Costliness X Anger interaction (β = .89, p = .02) helps clarify how such perceptions are related to the likelihood of getting even. Implications and future directions are discussed.
ReBAC2015: Interoperability of Relationship- and Role-Based Access Control
Creators: name: Rizvi, Syed Zain
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Computer Science
subject: Access Control
subject: relationship predicate
subject: protection state
subject: access control model
subject: authorization principal
subject: relationship based access control
subject: authorization procedure
subject: lazy evaluation
subject: role based access control
subject: demarcation hierarchy
subject: lazy authorization procedure
subject: authorization graph
subject: papr constraint
subject: strict grant semantic
subject: hybrid logic formula
subject: hybrid logic
subject: rebac model
subject: eager evaluation
subject: meap constraint
subject: predicate value caching
subject: privilege requirement
subject: Language Policy
subject: authorization decision
subject: model checking
subject: open source medical record system
subject: access control policy
subject: Social Network
subject: ReBAC2015

description: Relationship-Based Access Control (ReBAC) is a general-purpose access control paradigm for application domains in which authorization must take into account the relationship between the access requestor and the resource owner. This thesis presents an evolution of Fong's ReBAC model in two steps. First, I formalize and extend the first time implementation of ReBAC into a production-scale medical records system, OpenMRS. This extension incorporates sophisticated authorization schemes recently proposed in the literature, as well as a performance evaluation of these schemes. Second, the model is further extended to incorporate the notion of demarcations and authorization-time constraints. These extensions allow ReBAC to interoperate with legacy Role-Based Access Control at a fine-grained level, and significantly increase the expressiveness of the model. Also presented are the design of two authorization procedures (one of which has an algorithmic structure akin to an SMT solver) along with optimization techniques.
Pseudonicsara (Pseudonicsara) wanuma Ingrisch 2009, sp. n.
Creators: name: Ingrisch, Sigfrid
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Pseudonicsara
Pseudonicsara wanuma

description: Pseudonicsara (P.) wanuma sp. n. Figs. 458, 489, map 3. Holotype (female): Papua New Guinea, Madang Prov.: New Guinea, NE., Adelberg Mts. [= Adelbert Range], Wanuma [4° 35' S, 145° 10' E], 800–1000 m, 27.X.1958, J.L. Gressitt, depository: Bernice P. Bishop Museum, Honolulu, Hawaii, USA (BPBM). Diagnosis. The single female of the new species was collected together with P. abbreviata sp. n. It differs by the fastigium verticis having the dorsal margin straight, the female subgenital plate having a wide membranous central area, shallow basal grooves, and separate auricular lateral sclerites (Figs. 458, 489). Moreover, the ovipositor is longer and the face provided with a vertical black band that is missing in P. abbreviata. The latter character may however prove to be not diagnostic. The specific shape of the female subgenital plate also differs from that of other Pseudonicsara species. Description. Fastigium verticis with dorsal margin straight; tip angular; fastigium verticis in front of eyes 1.1 mm, from base 1.6 mm; dorsal eye length 1.7 mm; greatest diameter of eye 1.8 mm; index fastigium verticis from base: eye length 0.9. Male unknown. Female. Subgenital plate consisting of two short rounded lobes; each with a large shallow groove at base; both separated by a short grooved membranous central area divided by a median carina; a lateral carina at both sides of groove; with separate auricular lateral sclerites (Figs. 458, 489). Coloration. Medium brown, sides yellowish brown (green when alive?). Face with a vertical black band from median ocellus to clypeo-frontal suture. Tegmen with pattern of light veins and dark cells distinct. Measurements of female: body 27; pronotum 8.8; tegmen 35; hind femur 23; antenna 115; ovipositor 23 mm. Etymology. The name refers to the type locality; noun in apposition.
description: Published as part of Ingrisch, Sigfrid, 2009, Revision of the genus Pseudonicsara Karny, 1912 (Orthoptera: Tettigoniidae: Conocephalinae: Agraeciini) 2185, pp. 1-122 in Zootaxa 2185 on page 47
Effect of Cafeteria Diet Induced Obesity on Neuroinflammation in the Orbitofrontal Cortex
Creators: name: Kaur, Manpreet
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Education--Sciences
subject: Neuroscience
subject: Nutrition
subject: Psychology--Cognitive
subject: Cafeteria diet
subject: Orbitofrontal cortex
subject: Hippocampus
subject: Hypothalamus
subject: Cognitive inflexibilty
subject: Conditioned suppression behaviour
subject: Microglia
subject: Astrocytes
subject: Neuroinflammation
subject: Cytokines

description: Palatable food consumption is associated with obesity and induce inflammation in brain. The orbitofrontal cortex is implicated in compulsive behavior. Glial changes lead to synaptic remodeling and altered behavior. However it is not clear if metabolic changes associated with cafeteria diet consumption lead to glial changes in OFC. My study addressed this important question whether intake of cafeteria diet leads to glial changes in OFC. I observed that rats with extended access to cafeteria diet become obese, exhibited inflexible behaviour and increased GFAP and IBA1 expression in the hippocampus and the hypothalamus. Further, there was an increase observed in several proinflammatory cytokines in the hypothalamus. My work has shown that extended intake of cafeteria diet is associated with increased GFAP expression in OFC without any changes in IBA1 expression, proliferation and the levels of proinflammatory cytokines. This is the first study reporting astrocytic activation in OFC associated with compulsive food intake.
Genomic analysis of embryonic heart development in the mouse
Creators: name: Vrljičak, Pavle Josip
Publisher: name: University of British Columbia
Year: 2010

description: Malformations of the cardiovascular system are the most common type of birth defect in humans, affecting predominantly the formation of valves and septa. While many studies have addressed the role of specific genes during valve and septa formation, a global understanding is still largely incomplete. To address this deficit we have undertaken a genome-wide transcriptional profiling of the developing heart in the mouse. We generated and analyzed 19 Serial Analysis of Gene Expression (SAGE) libraries representing different regions of the mouse heart at multiple stages of embryonic development. We speculated that genes important for heart valve development would be differentially expressed in the valve forming regions, and have dynamic temporal expression patterns. We used our dataset to identify a novel list of valve enriched genes. Using k-means cluster analysis we also uncovered 14 distinct temporal gene expression patterns in the developing valves. Unique temporal expression patterns were found to be enriched for specific signalling pathway members and functional categories such as signal transduction, transcription factor activity, proliferation and apoptosis. The most highly expressed transcription factor within the developing valves was found to be Twist1. Analysis of gene expression changes in the Twist1 null developing valves revealed a novel phenotype consistent with a role of TWIST1 in controlling differentiation of mesenchymal cells following their transformation from endothelium in the mouse. Our data suggests that TWIST1 directly activates valve specific and cell motility gene expression in the atrio-ventricular canal, while suppressing expression of valve maturation markers. This work provides the first comprehensive temporal and spatial gene expression dataset for heart development during formation of the heart valves. It is a valuable resource for the elucidation of the molecular mechanisms underlying heart development.
Long-range adiabatic quantum state transfer through a linear array of quantum dots
Creators: name: Chen, Bing
name: Shen, Q. H.
name: Fan, Wei
name: Xu, Yan
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We introduce an adiabatic long-range quantum communication proposal based on a quantum dot array. By adiabatically varying the external gate voltage applied on the system, the quantum information encoded in the electron can be transported from one end dot to another. We numerically solve the Schrödinger equation for a system with a given number of quantum dots. It is shown that this scheme is a simple and efficient protocol to coherently manipulate the population transfer under suitable gate pulses. The dependence of the energy gap and the transfer time on system parameters is analyzed and shown numerically. We also investigate the adiabatic passage in a more realistic system in the presence of inevitable fabrication imperfections. This method provides guidance for future realizations of adiabatic quantum state transfer in experiments.
description: 7 pages, 7 figures
Motivic Classification of Regular Equivalued Orbits in the Exceptional Group G(2)
Creators: name: Nicholson, Jason
Publisher: name: Graduate Studies
Year: 2015
Subjects: subject: Mathematics
subject: FOS: Mathematics

description: We exhibit a motivic parameterization of conjugacy classes of equivalued regular semisimple elements in the Lie algebra of the exceptional group G(2) over local fields with residual characteristic at least 5.
Pseudonicsara (Pseudonicsara) wau Ingrisch 2009, sp. n.
Creators: name: Ingrisch, Sigfrid
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Pseudonicsara
Pseudonicsara wau

description: Pseudonicsara (P.) wau sp. n. Figs. 450, 494, map 1. Holotype (female): Papua New Guinea, Morobe Prov.: New Guinea (NE), Wau [7° 20' S, 146° 45' E], Morobe Dist., 1200 m, 21.IV.1963, J. Sedlacek, depository: Bernice P. Bishop Museum, Honolulu, Hawaii, USA (BPBM). Diagnosis. P. wau is similar to P. finister in that the subgenital plate is divided in midline by a membranous area and the lobes on proximal and lateral surfaces shallowly grooved. It differs from the latter by the lobes of the subgenital plate being triangular with subacute apex, the internal margin more concave, and the internal angle where both lobes meet not projecting (Figs. 450, 494). Differences to other species are outlined in the key. Description. Fastigium verticis in front of eyes 1.1 mm, from base 1.4 mm; dorsal eye length 1.5 mm; greatest diameter of eye 1.7 mm; index fastigium verticis from base: eye length 1.0. Face rugose but shining. Tegmen surpassing apices of hind femora; gradually narrowed behind basal widening. Femora with the following number of spines on ventral margins: fore femur 9 external, 6 internal; mid femur 6 external, 3 internal near base; hind femur 9–10 external, 5 minute internal near base. Male unknown. Female. Tenth abdominal tergite furrowed in midline [damaged]. Subgenital plate divided in midline by triangular membranous area; resulting lateral plates triangular, oblique; with lateral margins convex and longer than concave internal margins (Figs. 450, 494). Coloration. General colour yellowish brown. Face with black band between eyes including scapus; with another black band along clypeo-frontal suture extended on genae; a vertical band in midline reddish brown. Tegmen with pattern of dark cells and light veinlets little distinct. Measurements of female: body 27; pronotum 7.8; tegmen 27.5; hind femur 18; ovipositor 17.5 mm. Etymology. Named after the type locality; noun in apposition.
description: Published as part of Ingrisch, Sigfrid, 2009, Revision of the genus Pseudonicsara Karny, 1912 (Orthoptera: Tettigoniidae: Conocephalinae: Agraeciini) 2185, pp. 1-122 in Zootaxa 2185 on page 48
The North American Youth Club Sport Phenomena: An Investigation of Club Marketing Practice
Creators: name: Riker-Fox, John Joshua
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Marketing
subject: FOS: Economics and business
subject: Marketing
subject: sport

description: Organized youth sport is purposeful sport participation integrating a systematic schedule, directed by adults, and requiring substantial commitment (Kjønniksen, Anderssen, & Wold, 2009). Club sport enables competitive experience through team membership, promoting personal development, healthy behavior, and elite performances. Organized youth sport’s emerging challenge is to attract and retain membership that is well aligned with their club’s and coach’s philosophy, thereby maximizing the pleasure in, and length of their participation. Attrition remains a persistent challenge reflecting the internal failings of sports clubs (Jakobsson, Lundvall, Redelius, & Engström, 2012). Without a clearly articulated market offering, a club’s purpose is vague, and it fails to attract and retain the desired membership. Through the use of a qualitative methodology this thesis examines the youth club market space to better understand club types and consumer expectations. Emergent themes suggest the need for improved strategic club-athlete alignment in order to enhance the experience for stakeholders.