Prevalence of Helicobacter Pylori Infections and Associated Risk Factors Among Women of Child Bearing Ages in Selected Health Centers, Kolfe Keranio Sub City, Addis Ababa
Creators: name: Terfa, Kumera
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2015

description: Background: H.pylori is a gram-negative, spiral shaped, flagellated organism uniquely adapted to colonize the gastric mucous layer. It affects approximately one half of the world population and it is more prevalent in developing countries. The increased risk of infection is especially high occupational status,),(X2 =3.708, P=0.447), number of pregnancies (gravidity) (X2 =8.314, P=0.140), number of people in house hold (X2=2.479, P=0.140), gestational age (age of pregnancy) (X2 =7.879, P=0.069) and number of children ( parity) (X2=0.437,P=0.933). And some expected risk factors like habits of drinking alcohol (P=0.677), cigarette smoking (P=0.468), chat chewing (p= 0.818), drinking tea and coffee (P=0.757), using water for drinking (P=1) and Intestinal parasites (P=0.306) between H.pylori stool antigen test positive results, however, the study subjects who had a habits of drinking alcohol; cigarette smoking and chat chewing were very few in numbers. Conclusion: This study showed high prevalence of H.pylori infection among pregnant than non pregnant women. H.pylori infection was associated with a low hemoglobin value, history of gastrointestinal illness and presence of Hypermesisgravidum. H.pylori infected pregnant women showed high rate of anemia than non infected pregnant women. Some expected H.pylori associated risk factors like presence of intestinal parasites, smoking habit, chewing chat and drinking alcohol habit do not have significant association with H.pylori infection in this study. Key words: Anemia, H.pylori, pregnancy, Hemoglobin concentration, H. pylori Stool Antigen test among those living in the developing world due to precarious hygiene standards, crowded households and deficient sanitation associated with this part of the world. Methods: A cross-sectional study was conducted in kolfe keraniyo sub city in two health centers (Wereda-5 &amp; Woreda- 9) Addis Ababa, Ethiopia among child bearing ages of women, 195 pregnant and 137 non pregnant women matched for aged (16-40 years). A structured questionnaire was used to collect sociodemographic data of the study participants. Biological data such as blood samples were analyzed for determination of hemoglobin concentration and Stool samples were assessed for the presence of H.pylori infection by H.pylori stool antigens test kit and the presence of intestinal parasites were also assessed by direct stool examination (wet smear) and formol- ether concentration techniques. Data were summarized in frequencies (%) and mean (SD) as appropriate. Chi-square tests, logistic regression was used in the analysis as needed. In all cases P-value &lt;0.05 was considered as statistically significant. Results: The overall prevalence of H. pylori infection among study subjects of child bearing ages of women was 29 %( 96/332).The prevalence of H.pylori infection was higher in pregnant women than non pregnant women, 33.8% (66/195) among pregnant women and 21.9% (30 /137) among non pregnant women (X 2= 5.589 P value = 0.020). In this study there was statistically association between some association of risk factors and H.pylori infection like pregnancy status (OR1.825, 95%CI=1.105-3.014, P=0.020), history Hypermesisgravidum in pregnant women (OR=1.652 95%C.I=1.262-2.162, P=0.00), history of gastrointestinal illness and low hemoglobin value, (OR=5.259, 95% CI=2.978–14.449, p=0.003). There was no statistically significance between H.pylori stool antigen test positive results and sociodemographic characteristics of the study participants including like Maternal age (X2 =3.670, P=0.435), marital status (X2 =0.634, P=0.996), educational level (X2 =3.033, P=0.387)