cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Power Spectra Estimation for Weak Lensing
Creators: name: Hu, Wayne
name: White, Martin
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We develop a method for estimating the shear power spectra from weak lensing observations and test it on simulated data. Our method describes the shear field in terms of angular power spectra and cross correlation of the two shear modes which differ under parity transformations. Two of the three power spectra can be used to monitor unknown sources of noise in the data. The power spectra are decomposed in a model independent manner in terms of ``band-powers'' which are then extracted from the data using a quadratic estimator to find the maximum of the likelihood and its local curvature (for error estimates). We test the method against simulated data from Gaussian realizations and cosmological N-body simulations. In the Gaussian case, the mean bandpowers and their covariance are well recovered even for irregular (or sparsely) sampled fields. The mild non-Gaussianity of the N-body realizations causes a slight underestimation of the errors that becomes negligible for scales much larger than several arcminutes and does not bias the recovered band powers.
description: 7 pages, 5 figures, submitted to ApJ
Asymptotically simple spacetimes and mass loss due to gravitational waves
Creators: name: Saw, Vee-Liem
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The cosmological constant $Λ$ used to be a freedom in Einstein's theory of general relativity, where one had a proclivity to set it to zero purely for convenience. The signs of $Λ$ or $Λ$ being zero would describe universes with different properties. For instance, the conformal structure of spacetime directly depends on $Λ$: null infinity $\mathcal{I}$ is a spacelike, null, or timelike hypersurface, if $Λ>0$, $Λ=0$, or $Λ<0$, respectively. Recent observations of distant supernovae have taught us that our universe expands at an accelerated rate, and this can be accounted for by choosing $Λ>0$ in Einstein's theory of general relativity. A quantity that depends on the conformal structure of spacetime, especially on the nature of $\mathcal{I}$, is the Bondi mass which in turn dictates the mass loss of an isolated gravitating system due to energy carried away by gravitational waves. This problem of extending the Bondi mass to a universe with $Λ>0$ has spawned intense research activity over the past several years. Some aspects include a closer inspection on the conformal properties, working with linearisation, attempts using a Hamiltonian formulation based on "linearised" asymptotic symmetries, as well as obtaining the general asymptotic solutions of de Sitter-like spacetimes. We consolidate on the progress thus far from the various approaches that have been undertaken, as well as discuss the current open problems and possible directions in this area.
description: 41 pages, 2 figures
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 181 (11 H 754), 165 folios, f. 0027
Creators: name: de la Côte d'Or, Archives départementales
name: Projet CBMA
name: CG21/F.PETOT/2017
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0027, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0027, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
MOESM2 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 2: Figure S1. Verification of cre-1 gene deletions in selected transformants with co-transformation of only Cas12a and donor DNA, only crRNA and donor DNA, or only donor DNA. (A) Schematic of homologous recombination (HR) of target gene cre-1. (B–D) PCR analysis of cre-1 deletion with one primer (cre1-out-F) located upstream of the 5′ flanking region of genomic DNA and the other (cre1-in-R) located in the 3′ flanking region of genomic DNA. The expected length of disrupted transformants was 1.9 kb, while that of the WT host strain, used as a negative control, was 1.0 kb (rightmost lane). Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout). HDR, homology-directed repair; WT, wild type.
Effects of cation charges on the binding of stabilizers with human telomere and TERRA G-quadruplexes
Creators: name: Zhiguo Wang
name: Jianfeng Li
name: Liu, Jun-Ping
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Computational Biology

description: Both telomere and telomeric repeat-containing RNAs (TERRA) can fold into G-quadruplexes (G4) in eukaryotic cells. Given their key roles in the regulation of telomere length and translation, telomere and TERRA G4 are interesting targets of novel drug development strategies. It is known that the cation charge of a stabilizer is crucial to the binding of G4 and stabilizer. However, the quantitative relationship between the cation charge of a stabilizer and the binding strengths with telomere and TERRA G4 remain unclear. In the current study, by substituting positive charged TMPyP4 with neutral and negative charged groups, the effects of cation charges on the binding conformation and binding strength of porphyrin stabilizers are investigated via molecular docking and molecular dynamic (MD) simulations. The results show that all TMPyP4 analogs form stable binding complexes with telomere and TERRA G4 and that, stabilizer charges have limited effects on binding conformation and can hardly lead to any special conformational alternations of G4. Our hydrogen bond analysis shows that all stabilizers can hardly form stable intermolecular hydrogen bonds with G4. Regarding binding strength levels, a linear correlation is found between the binding free energies and cation charges of stabilizers in all G4‒stabilizer complexes, revealing the pivotal role of electrostatic interactions. The present work is the first to reveal a quantitative correlation between the charges and binding strengths of stabilizers in their binding with human telomere and TERRA G4, which will prove pivotal for G4 targeted drug design and development.
Chronology of single-cell transcriptome analysis from the point of view of molecular biological reaction
Creators: name: Sasagawa, Yohei
Publisher: name: figshare
Year: 2018
Subjects: subject: 60408 Genomics
subject: FOS: Biological sciences

description: Chronology of single-cell transcriptome analysis from the point of view of molecular biological technique.
Student reasoning about measurement uncertainty in an introductory lab course
Creators: name: Lewandowski, H. J.
name: Hobbs, Robert
name: Stanley, Jacob T.
name: Dounas-Frazer, Dimitri R.
name: Pollard, Benjamin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: Proficiency with calculating, reporting, and understanding measurement uncertainty is a nationally recognized learning outcome for undergraduate physics lab courses. The Physics Measurement Questionnaire (PMQ) is a research-based assessment tool that measures such understanding. The PMQ was designed to characterize student reasoning into point or set paradigms, where the set paradigm is more aligned with expert reasoning. We analyzed over 500 student open-ended responses collected at the beginning and the end of a traditional introductory lab course at the University of Colorado Boulder. We discuss changes in students' understanding over a semester by analyzing pre-post shifts in student responses regarding data collection, data analysis, and data comparison.
Dynamics of the peel front and the nature of acoustic emission during peeling of an adhesive tape
Creators: name: De, Rumi
name: Ananthakrishna, G.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate the peel front dynamics and acoustic emission of an adhesive tape within the context of a recent model by including an additional dissipative energy that mimics bursts of acoustic signals. We find that the nature of the peeling front can vary from smooth to stuck-peeled configuration depending on the values of dissipation coefficient, inertia of the roller, mass of the tape. Interestingly, we find that the distribution of AE bursts shows a power law statistics with two scaling regimes with increasing pull velocity as observed in experiments. In this regimes, the stuck-peeled configuration is similar to the `edge of peeling' reminiscent of a system driven to a critical state.
description: Accepted for publication in Phys. Rev. Lett
Acylphloroglucinols as kinase inhibitors from Sargassum nigrifoloides
Creators: name: Cheng-Shi Jiang
name: Yin-Yin Wang
name: Jin-Tong Song
name: Yu, Jin-Hai
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Three new acylphloroglucinols (1–3) and four known biosynthetically related analogs (4–7) were isolated from the ethanol extract of a brown alga Sargassum nigrifoloides. Structures for 1–7 were characterized via detailed spectroscopic analyses especially 2D NMR data. Screening of these compounds in Alzheimer’s diseases-related bioassays revealed moderate inhibitory activities against two therapeutically important kinases, CDK5 and GSK3β. A preliminary structure–activity relationship was also discussed.
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00474
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: LaMOP
subject: Chartes de la Bourgogne du Moyen Âge
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00474, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00474, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
On the Two-Point Correlation Function for the $U_q[SU(2)]$ Invariant Spin One-Half Heisenberg Chain at Roots of Unity
Creators: name: Hinrichsen, H.
name: Martin, P. P.
name: Rittenberg, V.
name: Scheunert, M.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Using $U_q[SU(2)]$ tensor calculus we compute the two-point scalar operators (TPSO), their averages on the ground-state give the two-point correlation functions. The TPSOs are identified as elements of the Temperley-Lieb algebra and a recurrence relation is given for them. We have not tempted to derive the analytic expressions for the correlation functions in the general case but got some partial results. For $q=e^{i π/3}$, all correlation functions are (trivially) zero, for $q=e^{i π/4}$, they are related in the continuum to the correlation functions of left-handed and right-handed Majorana fields in the half plane coupled by the boundary condition. In the case $q=e^{i π/6}$, one gets the correlation functions of Mittag's and Stephen's parafermions for the three-state Potts model. A diagrammatic approach to compute correlation functions is also presented.
description: 19 pages, LaTeX, BONN-HE-93-35
MOESM3 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Additional file 3: Figure S2. Verification of triple-gene deletions of cre-1, res-1 and gh1-1 in selected transformants by using Pooled single-crRNA-based CRISPR–Cas12a system (A) or crRNA Array-based CRISPR–Cas12a system (B). PCR analysis of triple-gene deletion of cre-1, res-1 and gh1-1 in selected transformants using one primer (cre1/res1/gh1-1-out-F) located upstream of the 5′ flanking region of genomic DNA and the other primer (cre1/res1/gh1-1-in-R) located in the 3′ flanking region of genomic DNA. The expected lengths of disrupted transformants of cre-1, res-1 and gh1-1 were 0.8, 0.7 and 1.9 kb, respectively, while those of WT strain (rightmost lane) was 1.2, 0.9 and 1.0 kb, respectively. Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout). The symbol of star indicated deletion mutant. HDR, homology-directed repair; WT, wild type. U6p, U6 promoter; Ptef1, tef1 promoter; TtrpC, trpC Terminator.
Lettre de Esprit-Claude-François Calvet à Jean-François Séguier, 1777-09-30
Creators: name: Calvet, Esprit-Claude-François
name: Esprit-Claude-François Calvet
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Epigraphie

description: [transcription] Monsieur et cher ami, j’ay envoyé avec sûreté à M. l’abbé de Saint-Véran à Vaison le paquet que vous m’avez adressé par le père recteur des collèges de Nismes, je luy avais de même fait parvenir le manuscrit emballé en toile cirée qu’un exprès me porta de votre part. Je ne doute pas que vous n’en ayez déjà reçu des nouvelles.

Je m’empresse de vous faire part de deux inscriptions qu’un officier de marine de mes amis m’a apporté de l’isle de Cos, je ne croye pas qu’elles ayent été jamais publiées, vous en ferez l’usage qu’il vous plaira. La première est très intéressante, l’autre est plus simple. Je les ay entendues avec la plus grande facilité malgré l’union des mots ordinaire aux grecs. Vous les trouverez au revers de cette page. Disposez toujours, monsieur et cher ami, de votre très humble et très obéissant serviteur,

Calvet.

Avignon, ce 30 septembre 1777.

ΦAMIAIAMON
MAXΩNKAIΨΠO
MNHMAKΨNHΓE
ΣIΩNNEMEPIOΨ
KAΣTPIKIOΨ
ΛEΨKIOΨTAKΩ
NIANOΨAΣIAPXOΨ
KAIAΨPHΛIAΣ
ΣAΠΦOΨΣΠΛA
TΩNOΣΛIKINNIA
NHΣAPXIEPEIHΣ
ΓΨNAIKOΣAΨTOΨ Trouvées à l’isle de Cos en 1777.

ΛIONΨ
ΣIOΨΠO
ΛEΩΣΚΩ
ΩΝΟΙΚΟ
ΝΟΜΟΨ
description: [personnes citées] Joseph-Dominique Fabre de Saint-Véran
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 140, fol. 198
description: Source: ark:/12148/btv1b10015185m
MOESM4 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 4: Figure S3. Verification of triple-gene deletions of gh1-1, cre-1 and res-1 in selected transformants with co-transformation of only three donor-DNAs without CRISPR expressing cassettes. (A) Schematic of homologous recombination (HR) of target genes mediated by each donor DNA. (B) PCR analysis of triple-gene deletion of gh1-1, cre-1 and res-1 in selected 23 transformants using one primer (cre1/gh1-1/res1-out-F) located upstream of the 5′ flanking region of genomic DNA and the other primer (cre1/gh1-1/res1-in-R) located in the 3′ flanking region of genomic DNA. The expected lengths of disrupted transformants of gh1-1, cre-1 and res-1 were 1.9, 0.8 and 0.7 kb, respectively, while those of the host strain (rightmost lane) was 1.0, 1.2 and 0.9 kb, respectively. Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout).
Splashing of liquids: interplay of surface roughness with surrounding gas
Creators: name: Xu, Lei
name: Barcos, Loreto
name: Nagel, Sidney R.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We investigate the interplay between substrate roughness and surrounding gas pressure in controlling the dynamics of splashing when a liquid drop hits a dry solid surface. We associate two distinct forms of splashing with each of these control parameters: prompt splashing is due to surface roughness and corona splashing is due to instabilities produced by the surrounding gas. The size distribution of ejected droplets reveals the length scales of the underlying droplet-creation process in both cases.
description: 6 pages, 6 figures
title: 01_2013
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
MOESM5 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 5: Figure S4. First round of target genomic editing by CRISPR–Cas9 system. (A) Schematic of homologous recombination (HR) of cre-1, res-1 and gh1-1 mediated by Cas9, sgRNAs and donor DNA. (B) PCR analysis of triple-gene deletion of cre-1, res-1 and gh1-1 in selected transformants using one primer (cre1/res1/gh1-1-out-F) located upstream of the 5′ flanking region of genomic DNA and the other primer (cre1/res1/gh1-1-in-R) located in the 3′ flanking region of genomic DNA. The expected lengths of disrupted transformants of cre-1, res-1 and gh1-1 were 0.8, 0.7 and 1.9 kb, respectively, while those of WT strain (rightmost lane) was 1.2, 0.9 and 1.0 kb, respectively. Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout). The symbol of star indicated deletion mutant. HDR, homology-directed repair; WT, wild type.
On the potential of Hg-Photo-CVD process for the low temperature growth of nano-crystalline silicon (Topical Review)
Creators: name: Barhdadi, A.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Mercury-Sensitized Photo-Assisted Chemical Vapor Deposition (Hg-Photo-CVD) technique opens new possibilities for reducing thin film growth temperature and producing novel semiconductor materials suitable for the future generation of high efficiency thin film solar cells onto low cost flexible plastic substrates. This paper provides an overview of this technique, with the emphasis on its potential in low temperature elaboration of nano-crystalline silicon for the development of thin films photovoltaic technology. Keywords: Photovoltaic, Solar Cell, Thin films, Nano-Crystalline Silicon, Hydrogenated Amorphous Silicon, Hydrogen Dilution, Low Temperature Growth, Photo-Chemical Vapor Deposition.
description: 26 pages, 8 figures, 131 references, Topical Review
The clinical implications of tests confirming COPD in subjects hospitalized with exacerbations
Creators: name: Pu, Chan Yeu
name: Quesada, Nancy
name: Lopez, Richard Nunez
name: Karmapath Aryal
name: Tulaimat, Aiman
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 60506 Virology
subject: FOS: Biological sciences

description: Background: The diagnosis of COPD in patients hospitalized for AECOPD can be confirmed by spirometry showing obstruction or radiographs showing emphysema. The evidence for COPD is sometimes absent or contradicts this diagnosis. The inaccurate attribution of the exacerbation to COPD can lead to suboptimal care and worse outcome. Objectives: We determined if the presence of tests that confirm the diagnosis of COPD has any implications on the course of the hospitalization and readmission rate. Methods: We selected subjects hospitalized between 2012 and 2014 for AECOPD. We divided them into four hierarchical, mutually exclusive groups based on the presence of tests that confirm the diagnosis of COPD: spirometry (COPDSPIRO), radiology (COPDRAD), clinical diagnosis (COPDCLIN), and no COPD by spirometry (NotCOPD). We compared the presentation, hospital course, outcome, and readmission rate between the four groups. Results: We identified 974 subjects: COPDSPIRO 22%, COPDRAD 24%, COPDCLIN 46% and 7% NotCOPD. The vital signs, use of respiratory support, admission to the MICU, and length of stay were similar between the groups. The age, gender, BMI, presence of comorbidities, and readmission rate were different between the groups. The NotCOPD group had the highest BMI (38 kg/m2), comorbidities, and 30-day all-cause readmission (17%). Logistic regression showed that serum creatinine and presence of any comorbidity were the independent predictors of 30-day all-cause readmission. Conclusion: COPD was confirmed by spirometry or radiographs in half of the subjects hospitalized for AECOPD. The presence of confirmation did not influence the hospital course. The presence of confirmation was associated with different readmission rate, but was accounted for by the presence of comorbidities.
Topological Hall effect from strong to weak coupling
Creators: name: Nakazawa, Kazuki
name: Bibes, Manuel
name: Kohno, Hiroshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Topological Hall effect (THE) of electrons coupled to a noncoplanar spin texture has been studied so far for the strong- and weak-coupling regimes separately; the former in terms of the Berry phase and the latter by perturbation theory. In this letter, we present a unified treatment in terms of spin gauge field by considering not only the adiabatic (Berry phase) component of the gauge field but also the nonadiabatic component. While only the adiabatic contribution is important in the strong-coupling regime, it is completely canceled by a part of the nonadiabatic contribution in the weak-coupling regime, where the THE is governed by the rest of the nonadiabatic terms. We found a new weak-coupling region that cannot be accessed by a simple perturbation theory, where the Hall conductivity is proportional to M, with 2M being the exchange splitting of the electron spectrum.
Entropy in the Mass-Energy Gravity Model: Energy Redistribution, Equilibrium, and the Nature of Disorder
Creators: name: Shreenan-Dyck, Chris
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 490204
subject: Mathematical aspects of general relativity

description: This paper extends the Mass-Energy Gravity (MEG) model by redefining entropy as a process of energy redistribution rather than a universal increase in disorder. In MEG, entropy is not driven by an absolute arrow of time but emerges from the way energy-density gradients (EDGs) dissipate over cosmic scales. This perspective challenges traditional thermodynamic interpretations by suggesting that entropy evolution depends on local energy conditions rather than a fixed time progression.We explore how entropy influences cosmic structure formation, its role in black hole dynamics, and whether mass-energy can ever reach true equilibrium. Unlike conventional models predicting inevitable heat death, MEG suggests that entropy’s behavior is shaped by the interaction between cosmic expansion and EDGs, which influence the persistence of large-scale structures over cosmic timescales. However, this does not imply that heat death is categorically avoided—rather, it suggests that the redistribution of energy through EDGs could delay or alter the conventional thermodynamic trajectory on cosmological scales.Finally, we propose observational tests to distinguish MEG’s entropy framework from standard thermodynamic models, including studies of black hole entropy limits, cosmic microwave background (CMB) fluctuations, and energy redistribution in large-scale structures.This work provides a novel perspective on entropy’s role in the universe, bridging gravitational dynamics, cosmology, and thermodynamics under a single, unified framework
W-Infinity Symmetry of the Nambu-Goto String in 4 Dimensions
Creators: name: Bakas, I.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a bosonic string propagating in 4--dim Minkowski space. We show that in the orthonormal gauge the classical system exhibits a hidden $W_{\infty}$ chiral symmetry, arising from the equivalence of its transverse modes with the $SU(2)/U(1)$ coset model defined on the string world--sheet. Generalizations to other string backgrounds are proposed. We also define a Liouville--like transformation that maps solutions of the $SU(2)/U(1)$ coset model into the solution space of two decoupled Liouville theories. Inverting this transformation, however, remains an open problem.
description: Latex, 12p
MOESM6 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Additional file 6: Figure S5. Second round of target genomic editing by CRISPR–Cas12a system. (A) Schematic of homologous recombination (HR) of neo, alp-1, rca-1 and hcr-1 mediated by Cas12a, array2 and donor DNA. (B) PCR analysis of quadruple-gene deletion of neo, alp-1, rca-1 and hcr-1 in selected transformants using one primer (gh1-1-out-F2, alp1/rca1/hcr1-out-F) located upstream of the 5′ flanking region of genomic DNA and the other primer (gh1-1-in-R2, alp1/rca1/hcr1-in-R) located in the 3′ flanking region of genomic DNA. The expected lengths of disrupted transformants of neo, alp1, rca-1 and hcr-1 were 0.8, 1.6, 5.0 and 0.7 kb, respectively, while those of the host strain (rightmost lane) was 1.9, 1.0, 0.6 and 1.0 kb, respectively. Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout). The symbol of star indicated deletion mutant. HDR, homology-directed repair; symbol star indicated deletion mutant.
X-ray imaging of the Seyfert 2 galaxy Circinus with Chandra
Creators: name: Sambruna, R. M.
name: Brandt, W. N.
name: Chartas, G.
name: Netzer, H.
name: Kaspi, S.
name: Garmire, G. P.
name: Nousek, J. A.
name: Weaver, K. A.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present results from the zeroth-order imaging of a Chandra HETGS observation of the nearby Seyfert 2 galaxy Circinus. Twelve X-ray sources were detected in the ACIS-S image of the galaxy, embedded in diffuse X-ray emission. The latter shows a prominent (~18arcsec) soft ``plume'' in the N-W direction, coincident with the [OIII] ionization cone. The radial profiles of the brightest X-ray source at various energies are consistent with an unresolved (FWHM ~0.8arcsec) component, which we identify as the active nucleus, plus two extended components with FWHMs ~ 2.3arcsec and 18arcsec, respectively. In a radius of 3arcsec, the nucleus contributes roughly the same flux as the extended components at the softest energies (< 2 keV). However, at harder energies (> 2 keV), the contribution of the nucleus is dominant. The zeroth-order ACIS spectrum of the nucleus exhibits emission lines at both soft and hard X-rays, including a prominent Fe Kalpha line at 6.4 keV, showing that most of the X-ray lines previously detected with ASCA originate in a compact region (<15 pc). Based on its X-ray spectrum, we argue that the 2.3arcsec extended component is scattered nuclear radiation from nearby ionized gas. The large-scale extended component includes the emission from the N-W plume and possibly from the outer starburst ring.
description: Figure 1 in color. ApJ Letters, in press
MOESM7 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 7: Figure S6. Verification of quadruple-gene deletions of neo, alp-1, rca-1 and hcr-1 in selected transformants with co-transformation of only four donor-DNAs without CRISPR expressing cassettes. (A) Schematic of homologous recombination (HR) of target genes mediated by each donor DNA. (B) PCR analysis of quadruple-gene deletion of neo, alp-1, rca-1 and hcr-1 in selected transformants using one primer (gh1-1-out-F2, alp1/rca1/hcr1-out-F) located upstream of the 5′ flanking region of genomic DNA and the other primer (gh1-1-in-R2, alp1/rca1/hcr1-in-R) located in the 3′ flanking region of genomic DNA. The expected lengths of disrupted transformants of neo, alp1, rca-1 and hcr-1 were 0.8, 1.6, 5.0 and 0.7 kb, respectively, while those of the host strain (rightmost lane) was 1.9, 1.0, 0.6 and 1.0 kb, respectively. Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout).
Assessment of Knowledge and Practices in Diabetes Management among Adults in Gwagwalada Federal Capital Territory Abuja, Nigeria
Creators: name: DANRAKA, ABUBAKAR
Publisher: name: MSI Publishers
Year: 2025
Subjects: Diabetes Management, Knowledge and Practices, Gwagwalada, FCT Abuja

description: A cross-sectional study assessed diabetes knowledge and practices among 150 residents of Gwagwalada, FCT, Nigeria. A random and convenient sampling was used to select the participants that were readily available from the general population resident in Gwagwalada. Collected data was analyzed using SPSS for frequencies, means and percentages of responses. Descriptive and inferential statistical analyses were determined using chi square test. Findings revealed significant gaps in awareness, with 66.7% unaware of target glucose levels and 27.3% uninformed about diabetes complications. Self-management was poor, with 63.3% failing to adhere to medications. Enhancing education and healthcare access is critical for better outcomes. Improving public education, promoting adherence, and addressing healthcare barriers are necessary to enhance diabetes management
A new lactam 28-norlimonoid from the leaves of Azadirachta indica A. Juss. (Meliaceae)
Creators: name: Nguyen, Nhi Y. T.
name: Dang, Phu H.
name: Nguyen, Van T. T.
name: Dang, Phuc H.
name: Tran, Quan L.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: From an EtOAc-soluble fraction of the leaves of Azadirachta indica, one new lactam 28-norlimonoid named nimbandiolactam-21 (1), together with 2 known limonoids (2 and 3) were isolated. Their relative structures were elucidated based on NMR spectroscopic analysis. Nimbandiolactone-23 (2) showed the most potent α-glucosidase inhibitory activity, with an IC50 value of 38.7 μM. Compound 1 represents the first naturally occurring example of a 28-norlimonoid having the lactam moiety. The plausible biosynthetic pathway for the formation of lactam moiety in 1 was proposed.
Phase transitions in the $q$-coloring of random hypergraphs
Creators: name: Gabrié, Marylou
name: Dani, Varsha
name: Semerjian, Guilhem
name: Zdeborová, Lenka
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Discrete Mathematics (cs.DM)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: We study in this paper the structure of solutions in the random hypergraph coloring problem and the phase transitions they undergo when the density of constraints is varied. Hypergraph coloring is a constraint satisfaction problem where each constraint includes $K$ variables that must be assigned one out of $q$ colors in such a way that there are no monochromatic constraints, i.e. there are at least two distinct colors in the set of variables belonging to every constraint. This problem generalizes naturally coloring of random graphs ($K=2$) and bicoloring of random hypergraphs ($q=2$), both of which were extensively studied in past works. The study of random hypergraph coloring gives us access to a case where both the size $q$ of the domain of the variables and the arity $K$ of the constraints can be varied at will. Our work provides explicit values and predictions for a number of phase transitions that were discovered in other constraint satisfaction problems but never evaluated before in hypergraph coloring. Among other cases we revisit the hypergraph bicoloring problem ($q=2$) where we find that for $K=3$ and $K=4$ the colorability threshold is not given by the one-step-replica-symmetry-breaking analysis as the latter is unstable towards more levels of replica symmetry breaking. We also unveil and discuss the coexistence of two different 1RSB solutions in the case of $q=2$, $K \ge 4$. Finally we present asymptotic expansions for the density of constraints at which various phase transitions occur, in the limit where $q$ and/or $K$ diverge.
description: 31 pages, 7 figures
MOESM8 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 8: Figure S7. Third round of target genomic editing by CRISPR–Cas12a system. (A) Schematic of homologous recombination (HR) of bar, ap-3 and prk-6 mediated by Cas12a, array2 and donor DNA. (B) PCR analysis of triple-gene deletion of bar, ap3 and prk6 in selected 22 transformants using one primer (alp1-out-F2, ap3/prk6-out-F) located upstream of the 5′ flanking region of genomic DNA and the other primer (alp1-in-R2, gh1-1/res1-in-R) located in the 3′ flanking region of genomic DNA. The expected lengths of disrupted transformants of bar, ap-3 and prk-6 were 0.8, 2.0 and 0.8 kb, respectively, while those of the host strain (rightmost lane) was 2.0, 1.2 and 1.2 kb, respectively. Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout). The symbol of star indicated deletion mutant. HDR, homology-directed repair.
ANRS - Jean-Michel Molina
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (5 pages). Autres destinataires : Jean-Claude Melchior, Roland Landman et al..
description: created: start=2008-10-05;end=2008-10-07
Quality and Proportion of Sexed X and Y Spermatozoa Using Different Percoll Density Gradient Centrifugation Methods After Freezing in Friesian Holstein Bulls
Creators: name: Chairun Nisa Aperi Simbolon, Anny Amaliya, Dhanis Fitriana, Aulia Puspita Anugra Yekti, Nurul Isnaini, Trinil Susilawati
Publisher: name: Zenodo
Year: 2024

description: The application of sexing technology represents a strategic endeavor to enhance the productivity of livestock farming by enabling the prediction of the sex of offspring, thereby aligning with the specific goals of the farm. This study focuses on evaluating the quality and distribution of sexed spermatozoa achieved through the use of the Percoll density gradient centrifugation method at varying Percoll densities. The research utilized fresh semen from three Friesian Holstein Bulls, each with an average age of 3.5 years and a body weight of 600 kg, and a minimum semen motility quality of 70%. Conducted as a laboratory experiment, this study employed two different treatments across ten replicates: T1 involved a 20%–65% Percoll density plus tris aminomethane egg yolk, while T2 utilized a 20%–60% Percoll density also combined with tris aminomethane egg yolk.The analysis incorporated a dependent t-test to assess the quality of the post-thaw sexed frozen semen, along with chi-square analysis to examine the proportion of X and Y spermatozoa. The findings revealed that varying the Percoll density within the gradient centrifugation sexing method did not affect the quality of the sexed frozen semen in terms of individual motility, viability, and abnormality rates for both the upper and lower layers. However, treatment T2 (20%–60% density) demonstrated superior outcomes in sperm concentration and total motile spermatozoa specifically in the lower layer, without significant differences observed in the upper layer. The spermatozoa proportions were as follows: in the upper layer, T1 had 19.60% X and 80.40% Y, while T2 had 18.60% X and 81.40% Y; in the bottom layer, T1 showed 78.10% X and 21.90% Y, whereas T2 had 79.20% X and 20.80% Y.In conclusion, both Percoll density treatments of 20%–65% and 20%–60% yielded high-quality spermatozoa, with individual motility percentages exceeding the SNI (Indonesian National Standard) threshold of >40%. Moreover, these treatments proved effective in separating X and Y spermatozoa, thereby demonstrating their potential utility in livestock breeding programs aimed at sex selection.
Transport properties of two-dimensional electron systems on silicon (111) surfaces
Creators: name: Hwang, E. H.
name: Sarma, S. Das
Publisher: name: arXiv
Year: 2006
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We theoretically study transport properties of a two-dimensional electron system on a hydrogen-passivated Si(111) surface in the field-effect-transistor (FET) configuration. We calculate the density and temperature dependent mobility and resistivity for the recently fabricated Si(111)-vacuum FET by using a semiclassical Boltzmann theory including screened charged impurity scattering. We find reasonable agreement with the corresponding experimental transport properties, indicating that the screened disorder potential from random charged impurities is the main scattering mechanism. We also find that the theoretical results with the valley degeneracy $g_v=2$ give much better agreement with experiment than the $g_v=6$ situation indicating that the usual bulk six-valley degeneracy of Si is lifted in this system.
description: 4 pages, 2 figures
Conservation Laws and Geometry of Perturbed Coset Models
Creators: name: Bakas, I.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a Lagrangian description of the $SU(2)/U(1)$ coset model perturbed by its first thermal operator. This is the simplest perturbation that changes sign under Krammers--Wannier duality. The resulting theory, which is a 2--component generalization of the sine--Gordon model, is then taken in Minkowski space. For negative values of the coupling constant $g$, it is classically equivalent to the $O(4)$ non--linear $\s$--model reduced in a certain frame. For $g > 0$, it describes the relativistic motion of vortices in a constant external field. Viewing the classical equations of motion as a zero curvature condition, we obtain recursive relations for the infinitely many conservation laws by the abelianization method of gauge connections. The higher spin currents are constructed entirely using an off--critical generalization of the $W_{\infty}$ generators. We give a geometric interpretation to the corresponding charges in terms of embeddings. Applications to the chirally invariant $U(2)$ Gross--Neveu model are also discussed.
description: Latex, 31p, CERN-TH.7047/93
MOESM9 of Upgrading of efficient and scalable CRISPR–Cas-mediated technology for genetic engineering in thermophilic fungus Myceliophthora thermophila
Creators: name: Liu, Qian
name: Zhang, Yongli
name: Li, Fangya
name: Li, Jingen
name: Sun, Wenliang
name: Tian, Chaoguang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 9: Figure S8. Verification of triple-gene deletions of bar, ap-3 and prk-6 in selected 22 transformants with co-transformation of three donor-DNAs without CRISPR expressing cassettes. (A) Schematic of homologous recombination (HR) of target genes mediated by donor DNA. (B) PCR analysis of triple-gene deletion of bar, ap-3 and prk-6 in selected 22 transformants using one primer (alp1-out-F2, ap3/prk6-out-F) located upstream of the 5′ flanking region of genomic DNA and the other primer (alp1-in-R2, gh1-1/res1-in-R) located in the 3′ flanking region of genomic DNA. The expected lengths of disrupted transformants of bar, ap-3 and prk-6 were 0.8, 2.0 and 0.8 kb, respectively, while those of the host strain (rightmost lane) was 2.0, 1.2 and 1.2 kb, respectively. Heterokaryotic transformants showed two PCR bands (both of wild-type and knockout). HDR, homology-directed repair.