cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy
Creators: name: Kaverina, Natalya
name: Borovjagin, Anton V.
name: Kadagidze, Zaira
name: Baryshnikov, Anatoly
name: Baryshnikova, Maria
name: Malin, Dmitry
name: Dhimankrishhna Ghosh
name: Nameeta Shah
name: Welch, Danny R.
name: Gabikian, Patrik
name: Karseladze, Apollon
name: Cobbs, Charles
name: Ulasov, Ilya V.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Formation of metastases, also known as cancer dissemination, is an important stage of breast cancer (BrCa) development. KISS1 expression is associated with inhibition of metastases development. Recently we have demonstrated that BrCa metastases to the brain exhibit low levels of KISS1 expression at both mRNA and protein levels. By using multicolor immunofluorescence and coculture techniques here we show that normal adult astrocytes in the brain are capable of promoting metastatic transformation of circulating breast cancer cells localized to the brain through secretion of chemokine CXCL12. The latter was found in this study to downregulate KISS1 expression at the post-transcriptional level via induction of microRNA-345 (MIR345). Furthermore, we demonstrated that ectopic expression of KISS1 downregulates ATG5 and ATG7, 2 key modulators of autophagy, and works concurrently with autophagy inhibitors, thereby implicating autophagy in the mechanism of KISS1-mediated BrCa metastatic transformation. We also found that expression of KISS1 in human breast tumor specimens inversely correlates with that of MMP9 and IL8, implicated in the mechanism of metastatic invasion, thereby supporting the role of KISS1 as a potential regulator of BrCa metastatic invasion in the brain. This conclusion is further supported by the ability of KISS1, ectopically overexpressed from an adenoviral vector in MDA-MB-231Br cells with silenced expression of the endogenous gene, to revert invasive phenotype of those cells. Taken together, our results strongly suggest that human adult astrocytes can promote brain invasion of the brain-localized circulating breast cancer cells by upregulating autophagy signaling pathways via the CXCL12-MIR345- KISS1 axis.
Blended Call Center with Idling Times during the Call Service
Creators: name: Legros, Benjamin
name: Oualid Jouini
name: Koole, Ger
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: We consider a blended call center with calls arriving over time and an infinitely backlogged amount of outbound jobs. Inbound calls have a non-preemptive priority over outbound jobs. The inbound call service is characterized by three successive stages where the second one is a break, i.e., there is no required interaction between the customer and the agent for a non-negligible duration. This leads to a new opportunity to efficiently split the agent time between inbound calls and outbound jobs. We focus on the optimization of the outbound job routing to agents. The objective is to maximize the expected throughput of outbound jobs subject to a constraint on the inbound call waiting time. We develop a general framework with two parameters for the outbound job routing to agents. One parameter controls the routing between calls, and the other does the control inside a call. We then derive structural results with regard to the optimization problem and numerically illustrate them. Various guidelines to call center managers are provided. In particular, we prove for the optimal routing that at least one of the two outbound job routing parameters has an extreme value.
In Pursuit of Health Equity: A History of Latin American Social Medicine
Creators: name: López, Raúl Necochea
Publisher: name: Duke University Press
Year: 2024

description: Eric D. Carter succeeds with this ambitious history of social medicine in Latin America.
Over seven chapters, plus an introduction and conclusion, we become reacquainted with
characters who have animated institutions and debates with local and global reach,
including Carlos Enrique Paz Soldan, Eduardo Cruz-Coke, Salvador Allende, Juan
Lazarte, and Josue de Castro. The story, however, is not so much powered by the people
whom it features as by the coherence found in social medicine as an intellectual and social
movement across the region.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0490
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0490, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0490, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Optimizing Cancer Prevention in Adolescents by Improving HPV Vaccine Delivery
Creators: name: Vielot, Nadja A.
name: Brewer, Noel T.
Publisher: name: North Carolina Institute of Medicine
Year: 2024

description: Routine HPV vaccination can prevent six cancers. Best practices for achieving high adolescent HPV vaccination coverage include automatically scheduled appointments, presumptive provider recommendations, standing orders, feedback on vaccination rates, and incentives. Promising practices include starting HPV vaccine recommendations and vaccine registry forecasting at age 9 and school entry requirements.
Systems thinking in geography: can high school students do it?
Creators: name: Cox, Marjolein
name: Elen, Jan
name: Steegen, An
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: An increasing interconnectedness of people and goods enhances the complexity of many geographical problems. For students to understand geography, systems thinking is a promising approach. It helps to understand increasing complexity by looking at the entire system and at the interconnectedness between the elements in the system. In order to develop adequate systems oriented teaching and learning the current state of the art of students’ systems thinking ability needs to be better understood. The authors developed a measuring tool in the form of a paper-and-pencil test in which 735 students in the last or penultimate year of secondary school (age 16–18 year) in Flanders, Belgium, took part. The main findings reveal a rather poor general level of students’ systems thinking ability. Students have many difficulties recognizing relationships between variables when several elements of systems thinking come together such as in feedback loops, interactions between human and physical environment, and a combination of different information sources. Rather great differences were found according to the students’ study background as well as an interaction effect between grade and gender of the students.
Mesolithic human and animal footprints at Lystep Haven, Pembrokeshire, 2010: the environmental context
Creators: name: Murphy, Kenneth
name: Caseldine, Astrid E
name: Barker, Louise
name: Fielding, S
name: Burrow, Steve
name: Carlsen, Sarah
Publisher: name: Archaeology Data Service
Year: 2019

description: Archaeologia Cambrensis, 163, 23-41
A ruthenium-carbamato-complex derived from a siloxylated amine and carbon dioxide for the oxidative a-cyanation of aromatic and cyclic tertiary amines
Creators: name: Kumar, Pawan
Publisher: name: figshare
Year: 2017
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: The rutheniumcarbamate complex derived from3-trimethoxysilyl-1-propyl amine and carbon dioxidewas found to be a novel catalyst forthe oxidative cyanation of aromatic and cyclic tertiary amines tocorresponding a-amino nitriles in high to excellent yields by usinghydrogen peroxide and molecular oxygen as enviro-economicoxidants. The developed protocol suggested an efficient alternativefor recycling carbon dioxide.
Visible light assisted photocatalytic reduction of CO2 using a graphene oxide supported heteroleptic ruthenium complex
Creators: name: Kumar, Pawan
Publisher: name: figshare
Year: 2017
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: A new heteroleptic ruthenium complex containing 2-thiophenyl benzimidazole ligands was synthesizedusing a microwave technique and was immobilized to graphene oxide via covalent attachment. The synthesizedcatalyst was used for the photoreduction of carbon dioxide under visible light irradiation withoutusing a sacrificial agent, which gave 2050 μmol g−1 cat methanol after 24 h of irradiation
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00451
Creators: name: de la Côte-d'Or, Archives départementales
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00451, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Assessing Interprofessional Collaboration at Clinical Learning Sites: Methodology on Developing the IP-CLEAR Tool
Creators: name: Sanders, Kimberly A.
name: Lynn, Mary R.
Publisher: name: North Carolina Institute of Medicine
Year: 2024

description: Interprofessional Clinical Learning Environment Assessment and Reflection (IP-CLEAR) tool was developed by a team of faculty from the schools of nursing, pharmacy, and medicine at University of North Carolina at Chapel Hill (UNC-CH), with the support of the North Carolina Area Health Education Consortium (NC AHEC) and the UNC-CH Office of Interprofessional Education and Practice (IPEP). The IP-CLEAR tool is intended for use by clinical sites that have or want to have clinical learners engaged and integrated into an excellent interprofessional CLE. The development of the IP-CLEAR and projections for future work are described here.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Cart. 190 (11 H 75), 316 folios, f. 0130v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0130v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0130v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
PEGylated magnetic nanoparticles (PEG@Fe3O4) as cost effectivealternative for oxidative cyanation of tertiary amines via C H activation
Creators: name: Kumar, Pawan
Publisher: name: figshare
Year: 2017
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: An efficient, cost effective and environmental friendly PEGylated magnetic nanoparticle catalyzed oxida-tive cyanation via CH activation of tertiary amines to corresponding -aminonitriles using hydrogenperoxide as oxidant and sodium cyanide as cyanide source is described. The synthesized nanocatalyst waseasily recovered with the help of external magnet and was successfully reused for several runs withoutany significant loss in catalytic activity.
Photo-induced reduction of CO2 using a magnetically separable Ru-CoPc@TiO2@SiO2@Fe3O4 catalyst under visible light irradiation
Creators: name: Kumar, Pawan
Publisher: name: figshare
Year: 2017
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: An efficient photo-induced reduction of CO2 using magnetically separable Ru-CoPc@TiO2@SiO2@Fe3O4as a heterogeneous catalyst in which CoPc and Ru(bpy)2phene complexes were attached to a solidsupport via covalent attachment under visible light is described. The as-synthesized catalyst was characterizedby a series of techniques including FTIR, UV-Vis, XRD, SEM, TEM, etc. and subsequently tested forthe photocatalytic reduction of carbon dioxide using triethylamine as a sacrificial donor and water as areaction medium. The developed photocatalyst exhibited a significantly higher catalytic activity to give amethanol yield of 2570.78 μmol per g cat after 48 h.
A graphene/hemin hybrid material as an efficient green catalyst for stereoselective olefination of aldehydes
Creators: name: Kumar, Pawan
Publisher: name: figshare
Year: 2017
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: A hemin/graphene composite, prepared by mixing an aqueous solution of graphene oxide (GO) with heminand sonicating the suspension for 5 h at room temperature, was investigated for olefination of aldehydesusing ethyl diazoacetate in the presence of triphenylphosphine. Efficient olefination of aromaticaldehydes with high (E)-selectivity was obtained, revealing that rGO/hemin is a promising heterogeneouscatalyst for the olefination reaction. The as-synthesized catalyst could easily be recovered from thereaction mixture and was subsequently used for several runs without any significantly loss in activity andselectivity.
Jon Shelton. The Education Myth: How Human Capital Trumped Social Democracy Ithaca, NY: Cornell University Press, 2023. 270 pp.
Creators: name: Goldsmith, William D.
Publisher: name: Cambridge University Press (CUP)
Year: 2024

description: Why did American economic inequality increase so much after 1980? Why has
European-style social democracy, with its more generous welfare state, struggled to
gain broader support from policymakers in the United States? Jon Shelton answers
these questions by arguing that policymakers of both parties—though principally
Democrats—bought into what he calls the “education myth,” the idea that “building
human capital through education represented the best, and increasingly, the only way
for Americans to access economic opportunity” (p. 3). Faith in this myth blotted out
paths to a broad social democracy, such as policies for strong labor unions, producerist
trade agreements, and full employment through job guarantees.
Nitrogen-doped graphene-supported copper complex: a novel photocatalyst for CO2 reduction under visible light irradiation
Creators: name: Kumar, Pawan
Publisher: name: figshare
Year: 2017
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: A copper(II) complex grafted to nitrogen-doped graphene (GrN700–CuC) was synthesized and thendemonstrated as an efficient photocatalyst for CO2 reduction into methanol under visible light irradiationusing a DMF/water mixture. The chemical and microstructural features of GrN700–CuC nanosheets werestudied by FTIR, XPS, XRD and HRTEM analyses. Owing to its truly heterogeneous nature, GrN700–CuCcould be easily recovered after the photocatalytic reaction and showed efficient recyclability forsubsequent runs
The Association of Selective Serotonin Reuptake Inhibitors with Delirium in Post-Operative Adults: A Secondary Analysis of a Post-Operative Dataset with Daily Severity of Illness Adjustment
Creators: name: Glier, Sarah
name: Bazemore, Imani
name: Carson, Shannon S.
name: Austin, C. Adrian
name: Yi, Joe
Publisher: name: European Delirium Association
Year: 2024

description:  Background Postoperative delirium is a prevalent condition associated with increased mortality, difficulties with physical recovery from surgery and decreased long-term cognitive function, especially in older adults. Currently, there are no direct medical treatments for delirium. We recently found an association between SSRI administration and reduced delirium in a critically ill medical population. We sought to evaluate this association in a surgical population. SSRIs may provide a new treatment option for delirium; further exploration is warranted. We aimed to assess the association between selective serotonin reuptake inhibitors (SSRIs) and delirium in postoperative adults.   Methods We undertook a secondary analysis of an existing cohort in a large Academic Medical Centre in the Southeast United States. Patients were adults (aged 18-99) requiring at least one night of hospital admission following a scheduled surgery, enrolled from July 2017 to September 2017. Our primary outcome was the incidence of delirium 24 hours after administration of an SSRI. Our exposure variable was any SSRI administration in the preceding 24 hours. We collected data on demographics, SSRI administration, overall severity of illness via the ASA grading system, and daily severity of illness via the Sequential Organ Failure Assessment (SOFA) score from the electronic medical record review.   Results We collected data on 191 patients (mean age 56.8 years, SD +/- 16.7). One hundred ten (57.6%) were female, and 149 (78%) were White. Most patients, 183 (95.8%), were non-Hispanic. Twenty-eight (14.6%) were prescribed SSRIs at any point during the study period and 35 (18.3%) were delirious on day one. Unadjusted analysis demonstrated that patients receiving SSRIs had OR 1.60 for delirium the next day (p=0.41). After adjusting for age ASA, age, hospital LOS, and SOFA, patients receiving SSRIs had OR 1.44 for next-day delirium (p=0.48).   Conclusions SSRIs administered in the postoperative period were not associated with delirium on the subsequent day. This finding conflicts with prior results from a critically ill population. The association of SSRIs with delirium requires further investigation.
D3.1 - Report on Key Challenges for Decision Making
Creators: name: Sterly, Simone
name: Wember, Carla
name: Peter, Sarah
name: Lang, Johannes
Publisher: name: Zenodo
Year: 2025

description: This deliverable gives an overview of the challenges that actors face in the CSP design and monitoring process in different EU Member States and throughout the design steps. Based on these challenges and drawing from the Tools4CAP inventory and literature review, it outlines good practices in the CSP design process as well as promising practices relating to other European and selected international policy strategy development processes with a particular emphasis on sustainable development.Based on the outcomes of 12 focus groups reports (see Deliverable 6.5), a literature review in 18 MS and a EU level online survey (n=38), the report shows what challenges emerge in the different MS at different policy steps and groups challenges into five clusters (Data coverage, availability and relevance; Current multi-level governance of the CAP and its complexity; Lack of capacities; Lack of accountability and transparency; Obstacles to evidence-based policy making). A joint analysis of the outcomes of the focus group reports, the literature analysis and the online survey shows that challenges resulting from the current multi-level governance of the CAP and its complexity as well as timing issues are the most common. Coordination between the national and the regional level, lack of transparency concerning decision-making processes or consultation results, as well as hurdles related to the volume and/or complexity of CAP documents and technical problems, are also among the most mentioned challenges.While there are some challenges, such as the complexity of the CAP’s architecture and timing issues, that need to be tackled at EU-policy level, new and improved tools are promising to tackle other challenges. This is exemplified in good practices of (a) tools for the prioritisation of needs and objectives, (b) tools to support intervention setting, coherence and impact assessment as well as (c) approaches for stakeholder consultation
D3.1 - Report on Key Challenges for Decision Making
Creators: name: Sterly, Simone
name: Wember, Carla
name: Peter, Sarah
name: Lang, Johannes
Publisher: name: Zenodo
Year: 2024

description: This deliverable gives an overview of the challenges that actors face in the CSP design and monitoring process in different EU Member States and throughout the design steps. Based on these challenges and drawing from the Tools4CAP inventory and literature review, it outlines good practices in the CSP design process as well as promising practices relating to other European and selected international policy strategy development processes with a particular emphasis on sustainable development.Based on the outcomes of 12 focus groups reports (see Deliverable 6.5), a literature review in 18 MS and a EU level online survey (n=38), the report shows what challenges emerge in the different MS at different policy steps and groups challenges into five clusters (Data coverage, availability and relevance; Current multi-level governance of the CAP and its complexity; Lack of capacities; Lack of accountability and transparency; Obstacles to evidence-based policy making). A joint analysis of the outcomes of the focus group reports, the literature analysis and the online survey shows that challenges resulting from the current multi-level governance of the CAP and its complexity as well as timing issues are the most common. Coordination between the national and the regional level, lack of transparency concerning decision-making processes or consultation results, as well as hurdles related to the volume and/or complexity of CAP documents and technical problems, are also among the most mentioned challenges.While there are some challenges, such as the complexity of the CAP’s architecture and timing issues, that need to be tackled at EU-policy level, new and improved tools are promising to tackle other challenges. This is exemplified in good practices of (a) tools for the prioritisation of needs and objectives, (b) tools to support intervention setting, coherence and impact assessment as well as (c) approaches for stakeholder consultation
Innovative technologies for monitoring and detection of diseases in aquatic animals
Creators: name: Ravikumar M. Chovatiaa, Parmar Bindiya Kirtikumara, Chandana Dinakaranb, Samad Sheikhb and Arpit Acharyab,*
Publisher: name: The Science world a Monthly e magazine
Year: 2024

description: The aquaculture sector has seen a significant jump in the production since last decade. The intensive farming practices has led to increased profitability to the farmers. The adaptation of best management practices (BMP) by the fisher’s community has led to the development of skilled and precise farming techniques. The use of multiple candidate species in farming and diversification in the culture practices has given a greater impact in the global aquaculture status. According to the "State of World Fisheries and Aquaculture 2022," aquaculture production for human consumption was 157 million tons, and by 2030, it is expected to rise by 15% to fulfil the growing need of the growing population. To protect natural resources for future generations, this increasing output must be more ecologically sustainable. Aquaculture production is impacted by a number of factors, including pollution, climate change, agricultural methods, legal concerns, water quality, and infections. Nonetheless, increased productivity and sustainability have resulted from the technological advancements in aquaculture. Aquaculture is utilizing advanced technology in several areas, such as marketing, genetics, nutrition and health management.
Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
Creators: name: Brown, Nicholas G
name: Bolhuis, Derek L
name: Wang, Xianxi
name: Mouery, Ryan D
name: Toomer, E Drew
name: Branigan, Timothy B
name: Robertson, Kevin C
name: Hsu, Carolyn
name: Bonacci, Thomas
name: Lukasik, Kimberly
name: Gupton, Stephanie L
name: Herring, Laura E
name: Emanuele, Michael J
name: Mills, C Allie
name: Canterbury, Owen G
Publisher: name: Elsevier
Year: 2024

description: Ubiquitination is an essential regulator of cell division. The kinase Polo-like kinase 1 (PLK1) promotes protein degradation at G2/M phase through the E3 ubiquitin ligase Skp1-Cul1-F box (SCF)βTrCP. However, the magnitude to which PLK1 shapes the mitotic proteome is uncharacterized. Combining quantitative proteomics with pharmacologic PLK1 inhibition revealed a widespread, PLK1-dependent program of protein breakdown at G2/M. We validated many PLK1-regulated proteins, including substrates of the cell-cycle E3 SCFCyclin F, demonstrating that PLK1 promotes proteolysis through at least two distinct E3 ligases. We show that the protein-kinase-A-anchoring protein A-kinase anchor protein 2 (AKAP2) is cell-cycle regulated and that its mitotic degradation is dependent on the PLK1/βTrCP signaling axis. Expression of a non-degradable AKAP2 mutant resulted in actin defects and aberrant mitotic spindles, suggesting that AKAP2 degradation coordinates cytoskeletal organization during mitosis. These findings uncover PLK1's far-reaching role in shaping the mitotic proteome post-translationally and have potential implications in malignancies where PLK1 is upregulated.
Relevant Materials for "Profiles in First-Year College Students" Manuscript Direction
Creators: name: Ell, Mikayla
name: Booker, Jordan Ashton
name: Phan, Tracy
name: Kelton, Robyn
name: Fivush, Robyn
name: Wainryb, Cecilia
name: Greenhoot, Andrea
name: McLean, Kate C.
name: Southwick, Maia Lynn
name: Pasupathi, Monisha
Publisher: name: OSF Registries
Year: 2023
Subjects: COVID-19
College adjustment
Emerging adults
Identity development
Mental health

description: This component contains de-identified data, syntax, and supplemental information relevant for the pre-registered manuscript direction addressing interrelations and variability among first-year students' self-reports of psychosocial functioning against the backdrop of the COVID-19 pandemic
Octahedral rhenium K4[Re6S8(CN)6] and Cu(OH)2cluster modifiedTiO2for the photoreduction of CO2under visible light irradiation
Creators: name: Kumar, Pawan
Publisher: name: figshare
Year: 2017
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: tOctahedral hexacyano rhenium K4[Re6S8(CN)6] cluster complexes were grafted onto photoactive Cu(OH)2cluster modified TiO2{Cu(OH)2/TiO2} support. The rhenium and copper cluster modified TiO2photocata-lyst combines the advantages of heterogeneous catalyst (facile recovery, recycling ability of the catalyst)with the reactivity, selectivity of the soluble molecular catalyst. The synthesized heterogeneous cata-lyst was found to be highly efficient photoredox catalyst for the reduction of CO2under visible lightirradiation. Methanol was found to be the major liquid product with the formation of hydrogen as a byproduct as determined with GC-FID and GC-TCD, respectively. The methanol yield after 24 h irradiationwas found to be 149 mol/0.1 g cat. for Re-cluster@Cu(OH)2/TiO2photocatalyst that is much higher than35 mol/0.1 g cat. for Cu(OH)2/TiO2and 75 mol/0.1 g cat. for equimolar rhenium cluster in the presenceof triethanolamine (TEOA) as a sacrificial donor. The quantum yields ( MeOH) of Re-cluster@Cu(OH)2/TiO2and Cu(OH)2/TiO2were found to be 0.018 and 0.004 mol einstein−1, respectively. These values are muchhigher than those reported for other heterogeneous catalysts for six electron transfer reaction.
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0983
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: cartulaire
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0983, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0983, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Supplementary: The socio-economic consequences of Cushing’s syndrome: a nationwide cohort study
Creators: name: Ebbehoj, Andreas
name: Søndergaard, Esben
name: Jepsen, Peter
name: Stochholm, Kirstine
name: Svane, Helene Matilde Lundsgaard
name: Madsen, Morten
name: Poulsen, Per Løgstrup
name: Jørgensen, Jens Otto L
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: Supplementary to: The socio-economic consequences of Cushing’s syndrome: a nationwide cohort study
Paper is currently under review.

Contents:- Supplementary section 1: Algorithm for identifying CS patients- Supplementary section 2: Validation of algorithm- Supplementary section 3: Details on socio-economic outcomes- Supplementary results- STROBE-RECORD checklist
Collaborative Research: ABI Development: Enabling Species Interaction Research Using Specimens and Observations (Associate!)
Creators: name: Seltmann, Katja
name: Poelen, Jorrit
name: Franz, Nico
name: Gilbert, Edward
Publisher: name: figshare
Year: 2017
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: The project summary and description for the 2017 version of the Associate! project. Associate! is a software ecosystem to facilitate research about species interactions, synthesize new data that include them, and to combine extant species interaction data resources, yielding new knowledge bases and services.
Exports, immigration and human capital in US states
Creators: name: Sucharita Ghosh
name: Mastromarco, Camilla
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Plant Biology

description: Using a Bayesian approach we estimate a stochastic frontier model to measure the productivity effects of state-level exports and immigration to each of the 50 US states. The results show that state productivity is affected positively by both state exports and immigrants arriving with embodied human capital. The efficiency model also reveals that the interaction of incoming immigrants with previously accumulated human capital in the host state improves state efficiency.
Progression towards smoking cessation: Qualitative analysis of successful, unsuccessful, and never quitters
Creators: name: Tombor, Ildiko
name: Vangeli, Eleni
name: West, Robert
name: Shahab, Lion
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background: Understanding how people transition between phases of not making a quit attempt to stopping smoking successfully is important in order to optimize interventions. This study aimed to explore differences in attitudes towards smoking and quitting among smokers and ex-smokers. Methods: Adult (age 18 and over) successful (n = 8), unsuccessful (n = 8) and never quitters (n = 7) were recruited through stop-smoking services in England. Semi-structured interviews were conducted and data were analysed using framework analysis. Results: Seven themes (starting to smoke, positive appraisal of smoking, responsibility for past/current smoking, negative effects of smoking, reasons to quit, process of quitting, and identity) were identified in all groups. Sub-group differences were explored and used to derive six typologies with descriptive characteristics: committed smokers, aware smokers, forced attempters, struggling attempters, pragmatic ex-smokers, and committed non-smokers. Using these typologies and the smallest number of differentiating factors between them (awareness of negative effects, motivation to stop and acceptance of responsibility), a parsimonious model of progression towards smoking cessation was developed. Conclusions: Awareness of negative effects, motivation and, crucially, a sense of commitment for taking responsibility to take actions towards behavior change may be important for whether smokers attempt to quit and progress to a successful quit attempt.
Recent work in the environs of Brecon Gaer Roman fort
Creators: name: Hankinson, Richard
name: Lewis, J P
name: Chapman, Evan M
name: Toller, Hugh
name: Webster, Peter V
name: Owen, Wendy
name: Silvester, Bob
Publisher: name: Archaeology Data Service
Year: 2019

description: Archaeologia Cambrensis, 164, 89-130
Investigating Cu-Site Doped Cu–Sb–S Nanoparticles Using Photoelectron and Electron Paramagnetic Resonance Spectroscopy
Creators: name: Donley, Carrie L.
name: George, Gavin M.
name: Jarocha, Lauren E.
name: Kerpal, Christian
name: Matthias, Brad R.
name: Daniel, Jacob E.
name: Golden, River
name: Anderson, Mary E.
name: Weaver, S. Ivan
Publisher: name: American Chemical Society (ACS)
Year: 2024

description: Tetrahedrite (Cu12Sb4S13) and famatinite (Cu3SbS4) are good candidates for green energy applications because they possess promising thermoelectric and photovoltaic properties as well as contain earth-abundant and nontoxic constituents. Herein, X-ray photoelectron spectroscopy (XPS), ultraviolet photoelectron spectroscopy (UPS), and electron paramagnetic resonance spectroscopy (EPR) methods examined inherent electronic properties and interatomic magnetic interactions of Cu-site doped tetrahedrite and famatinite nanomaterials. An energy-efficient modified polyol method was utilized for the synthesis of tetrahedrite and famatinite nanoparticles doped on the Cu-site with Zn, Fe, Ni, Mn, and Co. This is the first parallel study of tetrahedrite and famatinite nanomaterials with XPS, UPS, and EPR methods alongside a systematic analysis of dopant-dependent effects on the electronic structure and magnetic interactions for each material. XPS showed that the Cu and Sb species in tetrahedrite and famatinite possess different oxidation states, while UPS characterization reveals larger dopant-dependent shifts in the work function for tetrahedrite nanoparticles (4.21 to 4.79 eV) than for famatinite nanoparticles (4.57 to 4.77 eV). Finally, all famatinite nanoparticles display an EPR signal, indicating trace amounts of paramagnetic Cu(II) present below the detection limit of XPS. For tetrahedrite, EPR signatures were observed only for the Zn-doped and Mn-doped nanoparticles, suggesting signal broadening from Cu–Cu spin exchange or spin–lattice relaxation. This study demonstrates the complementary nature of XPS and EPR techniques for studying the oxidation states of metals in solid-state nanomaterials. Comparing the electronic and magnetic properties of tetrahedrite and famatinite while studying the impact of dopant incorporation will guide future endeavors in designing sustainable, high-performance materials for renewable energy applications.
TokenMotion: Motion-Guided Vision Transformer For Video Camouflaged Object Detection Via Learnable Token Selection
Creators: Zifan Yu
Erfan Bank Tavakoli
Meida Chen
Suya You
Raghuveer Rao
Sanjeev Agarwal
and Fengbo Ren
Publisher: name: IEEE Signal Processing Society
Year: 2024

description: The area of Video Camouflaged Object Detection (VCOD) presents unique challenges in the field of computer vision due to texture similarities between target objects and their surroundings, as well as irregular motion patterns caused by both objects and camera movement. In this paper, we introduce TokenMotion (TMNet), which employs a transformer-based model to enhance VCOD by extracting motion-guided features using a learnable token selection. Evaluated on the challenging MoCA-Mask dataset, TMNet achieves state-of-the-art performance in VCOD. It outperforms the existing state-of-the-art method by a 1.7\% improvement in weighted F-measure, an 1.7% enhancement in S-measure, and a 2.1\% boost in mean Dice. The results demonstrate the benefits of utilizing motion-guided features via learnable token selection within a transformer-based framework to tackle the intricate task of VCOD. The code of our work will be available when the paper is accepted.
XIVA XONLARI ARXIV HUJJATLARIDA QORAQALPOQLAR TARIXIGA OID MA'LUMOTLAR
Creators: name: SADIKOV, ABDUMUMIN
Publisher: name: Zenodo
Year: 2024

description: Qoraqalpoqlarning tarixi Markaziy Osiyodagi muhim etnik guruh sifatida ko‘pincha mif va rivoyatlar ostida yashiringan.  Biroq,  Xiva xonlari arxivlarida saqlanayotgan arxiv hujjatlari bu xalqning o‘tmishi haqida qimmatli ma’lumot manbai hisoblanadi.  Ushbu maqolada biz asosiy voqealarni, Xiva xonligining ularning taqdiriga ta’sirini ochib berish, shuningdek, o‘tmishdagi etnik guruhlar o‘rtasidagi munosabatlarni aniqlash maqsadida ushbu hujjatlar asosida qoraqalpoqlar tarixini o‘rganamiz.  Arxiv materiallarini tahlil qilish qoraqalpoqlarning tarixini, mintaqaning madaniy-siyosiy landshaftidagi o‘rnini chuqurroq o‘rganishga yordam beradi.
Azure at the Turing: Talk from Microsoft Azure HPC for research round table on 05 October 2017
Creators: name: O'Reilly, Martin
Publisher: name: figshare
Year: 2017
Subjects: subject: Distributed Computing
subject: FOS: Computer and information sciences

description: An overview of how The Alan Turing Institute is using Azure to support its research programme. The talk describes how we use Azure at the Turing and discusses the benefits and challenges of using the cloud for our primary institutional level compute resource. It discusses how we support researchers in using Azure and how we hope to make cloud computing easier for our researchers in future, highlighting some excellent work being done at UCL in this direction.

Presented at a Microsoft Azure HPC for research round table in London on 05 October 2017.
Roman coin hoard and enclosure at Jamesford, near Montgomery
Creators: name: Hankinson, Richard
name: Grant, Ian
name: Jones, Nigel
name: Britnell, William J
name: Besly, Edward
name: Webster, Peter V
name: Caseldine, Astrid E
name: Griffiths, Catherine J
Publisher: name: Archaeology Data Service
Year: 2019

description: Archaeologia Cambrensis, 161, 233-248
The role of astrocytes in prion-like mechanisms of neurodegeneration.
Creators: name: Smethurst, Phillip
name: Franklin, Hannah
name: Clarke, Benjamin E
name: Sidle, Katie
name: Patani, Rickie
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Stem Cells
subject: Cell Biology

description: Accumulating evidence suggests that neurodegenerative diseases are not merely neuronal in nature but comprise multicellular involvement, with astrocytes emerging as key players. The pathomechanisms of several neurodegenerative diseases involve the deposition of misfolded protein aggregates in neurons that have characteristic prion-like behaviours such as template-directed seeding, intercellular propagation, distinct conformational strains and protein-mediated toxicity. The role of astrocytes in dealing with these pathological prion-like protein aggregates and whether their responses either protect from or conspire with the disease process is currently unclear. Here we review the existing literature implicating astrocytes in multiple neurodegenerative proteinopathies with a focus on prion-like behaviour in this context.
Facile one-pot synthesis of new [1,2,4]triazolo[1,5-a]pyridine derivatives by ultrasonic irradiation
Creators: name: Lazhar Zribi
name: Zribi, Fathi
name: Marco-Contelles, José
name: Fakher Chabchoub
name: Lhassane Ismaili
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Herein, we report an ultrasonic promoted facile and convenient “one-pot” procedure for the synthesis of new [1,2,4]triazolo[1,5-a]pyridine derivatives 3, 4 and 5, using Amberlite IRA-400, in short reaction times and high yields and its comparison with classical reaction conditions. The structures of new compounds were assigned with the help of analytical 1H, 13C NMR, and mass spectral studies.
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00179
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00179, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00179, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Aerosol diffusion battery: The retrieval of particle size distribution with the help of analytical formulas
Creators: name: A. A. Onischuk
name: A. M. Baklanov
name: S. V. Valiulin
name: P. P. Moiseenko
name: V. G. Mitrochenko
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Hematology

description: A new algorithm is proposed for the determination of aerosol particle size distribution from a set of screen diffusion battery penetrations. The idea is to determine the size spectra of the fractions of particles separated by the sections of diffusion battery, so the total size distribution is the sum of the spectra of fractions. The spectrum of each fraction is approximated by the lognormal function, which is defined by two parameters: the standard geometric deviation (SGD) and geometric mean diameter. The SGD value is chosen to be 1.35 for each fraction. The geometric mean diameters of fractions are calculated from the diffusion battery penetrations. For this purpose, analytical formulas are derived to link the mean single-fiber collection efficiency for each fraction with the experimentally measured penetrations. Then the mean diameters of fractions are calculated from the collection efficiencies using the fan model filtration theory. To achieve a better size resolution, numerical approach is proposed to calculate the particle size spectrum using the analytical solution as an initial approximation. The validity of the analytical and numerical solutions is investigated by comparing them with the spectra determined by means of transmission electron microscopy and gravity settling. For this purpose, the aerosol is generated using the evaporation-nucleation technique, Collison-type nebulizer, and hot-wire bulb generator. It is found that the analytical solution demonstrates a good sizing accuracy but relatively poor size resolution, while the numerical approach results in both good sizing accuracy and good size resolution for the two-mode aerosol. Copyright © 2018 American Association for Aerosol Research