cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Procoagulant microparticles promote coagulation in a factor XI-dependent manner in human endotoxemia
Creators: name: Bradford,
name: Key,
name: Mooberry,
name: Hobl,
name: Lin,
name: Jilma,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Human endotoxemia is characterized by acute inflammation and activation of coagulation, as well as increased numbers of circulating microparticles (MPs). Whether these MPs directly promote coagulation and through which pathway their actions are mediated, however, has not been fully explored.
APPLICATION DU CONCEPT D'IMPACTION VIRTUELLE A LA FILTRATION
Creators: name: B. SAGOT
name: D. LE DUR
Publisher: name: Association Française d'Etudes et de Recherches sur les Aérosols (ASFERA)
Year: 2019
Subjects: subject: impacteurs virtuel
subject: diamètre de coupure
subject: séparation gaz particule
subject: virtual impactor
subject: cutoff diameter
subject: particle separation

description: Le concept d'épuration de gaz chargé en particules via le concept d'impacteur virtuel a été récemment breveté. L'objectif de cette étude expérimentale est la conception et l'intégration de ce concept pour des débits élevés. La conception finale qui a été testée est composée de 396 buses d'accélération d'un diamètre 1.2 mm. Elle a été testée à un débit de 50 m3.h-1, et a montré qu'on obtenait alors un diamètre aérodynamique de coupure de 1.4 µm, avec une efficacité de collecte supérieure à 90% pour des particules de diamètre supérieur à 2.5 µm
APPLICATION OF SCIENTIFIC FISH CULTURE PRACTICES AMONG KOLLAM DISTRICT'S MARINE HUMAN CAPITAL
Creators: name: Ambilikumar2, Santhakumar V S1 V
Publisher: name: Zenodo
Year: 2022

description: Abstract Fish culture is a major economic activity in Assam, providing money and employment to a segment of the people (Shrivastava, 1994). Due to the state's scarcity of fish production, the middle and lower classes spend a large portion of their income on purchasing fish at excessive costs. Because the man-to-land ratio is decreasing, agriculture cannot bear the whole load of feeding the region's population. In this sense, fish cultivation in underutilised water resources will be the greatest alternative for meeting India's protein requirements. Fish farming is an economic activity since fish farmers produce and sell fish. Others buy and consume the fish. The present research aims to examine the issues of fish farming techniques, social engagement, and training of Kollam district's marine human resource. 260 maritime fishermen in the Kollam district were surveyed for this purpose. The fish farmer is referred to as a producer because he raises and cares for the fish in the same way that he would any other crop or animal. People are drawn to fish farming for a variety of reasons, including higher wages than agriculture, use of inherited water regions, and increased demand for fish, as well as the possibility to generate money from other activities in the area where the farmer resides. If the primary motive is to make money, he would most likely grow as many fish as he can via fish farming. If his aim is just to continue on the family legacy of fish farming, he may be more concerned with producing enough fish for his family than with making money.
A quick guide to peer review
Creators: name: Mehmani, Bahar
Publisher: name: Zenodo
Year: 2023
Subjects: peer review

description: In this deck I take the audience on the definition of peer review, how the research community thinks about it, how as an editor you can find willing and relevant reviewers, and how to write a constructive and high-quality peer review report.
description: {"references": ["https://researcheracademy.elsevier.com/navigating-peer-review/certified-peer-reviewer-course", "https://ease.org.uk/communities/peer-review-committee/peer-review-toolkit/", "https://beta.elsevier.com/reviewer/how-to-review/structured-peer-review?trial=true", "https://peerreviewweek.wordpress.com/"]}
Selaginella diffusa Spring, Bull. Acad. Roy. Sci. Bruxelles
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Lycopodiopsida
Selaginellales
Selaginellaceae
Selaginella
Selaginella diffusa

description: Selaginella diffusa (C.Presl) Spring, Bull. Acad. Roy. Sci. Bruxelles 10: 143. 1843.
 Range: —Mountains from Costa Rica east to Suriname and Trinidad, south to Bolivia (CO, LP).
 Ecology: —Common; terrestrial, prostrate with erect branch tips, sometimes forming large colonies, in humid forests, on steep banks, on logs, and among rocks; 400–3200 m.
 Notes: —A confusingly variable species, especially in size, but also in degree of development of auricles on the axillary leaves. A related species, Selaginella lingulata Spring, from Colombia to Peru, has been reported from Bolivia by Alston et al. (1981), who cited Bang 909 (US; but cited by them as S. diffusa in BM!) and Tate 1076 (US), but we believe that both collections, the former seen in UC, the latter determined by M. Sundue in NY, are better identified as S. diffusa; Tryon & Stolze (1994) echoed the presence of S. lingulata in Bolivia, without citing specimens. It differs from S. diffusa by its basally ciliolate lateral leaves without auricles (vs. lateral leaves long-ciliate, biauriculate, cilia often 2 or more cells).
 Another closely related species is S. horizontalis (C.Presl) Spring, from Costa Rica to Ecuador; it differs from S. diffusa in having narrowly oblong lateral leaves (vs. ovate), in having unicellular cilia at the base of the lateral leaves (vs. mostly 2- or more celled), and having medial leaves aristate (vs. acute or acuminate), each with a single auricle (vs. with two auricles, the inner one sometimes rudimentary).
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. III. Selaginellaceae, pp. 248-258 in Phytotaxa 344 (3) on pages 252-253, DOI: 10.11646/phytotaxa.344.3.5, http://zenodo.org/record/13719508
XMCD studies of thin Co films on BaTiO$_3$
Creators: name: Welke, Martin
name: Gräfe, Joachim
name: Govind, Remya Kunjuveettil
name: Babu, Vasili Hari
name: Trautmann, Martin
name: Schindler, Karl-Michael
name: Denecke, Reinhard
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Different layer thicknesses of Cobalt ranging from 2.6 Å (1.5 ML) up to 55 Å (30.5 ML) deposited on ferroelectric BaTiO$_3$ have been studied regarding their magnetic behavior. The layers have been characterized using XMCD spectroscopy at remanent magnetization. After careful data analysis the magnetic moments of the Cobalt could be determined using the sum rule formalism. There is a sudden and abrupt onset in magnetism starting at thicknesses of 9 Å (5 ML) of Cobalt for measurements at 120 K and of 10 Å (5.5 ML) if measured at room temperature. Initial island growth and subsequent coalescence of Co on BaTiO$_3$ is suggested to explain the sudden onset. In that context, no magnetically dead layers are observed.
description: 9 pages, 5 figures, submitted to J. Phys. Condens. Matter
Structural and functional insights into enzymes of the vitamin K cycle
Creators: name: Tie,
name: Stafford, Darrel W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Vitamin K-dependent proteins require carboxylation of certain glutamates for their biological functions. The enzymes involved in the vitamin K-dependent carboxylation include: gamma-glutamyl carboxylase (GGCX), vitamin K epoxide reductase (VKOR) and an as-yet-unidentified vitamin K reductase (VKR). Due to the hydrophobicity of vitamin K, these enzymes are likely to be integral membrane proteins that reside in the endoplasmic reticulum. Therefore, structure-function studies on these enzymes have been challenging, and some of the results are notably controversial. Patients with naturally occurring mutations in these enzymes, who mainly exhibit bleeding disorders or are resistant to oral anticoagulant treatment, provide valuable information for the functional study of the vitamin K cycle enzymes. In this review, we discuss: (i) the discovery of the enzymatic activities and gene identifications of the vitamin K cycle enzymes; (ii) the identification of their functionally important regions and their active site residues; (iii) the membrane topology studies of GGCX and VKOR; and (iv) the controversial issues regarding the structure and function studies of these enzymes, particularly, the membrane topology, the role of the conserved cysteines and the mechanism of active site regeneration of VKOR. We also discuss the possibility that a paralogous protein of VKOR, VKOR-like 1 (VKORL1), is involved in the vitamin K cycle, and the importance of and possible approaches for identifying the unknown VKR. Overall, we describe the accomplishments and the remaining questions in regard to the structure and function studies of the enzymes in the vitamin K cycle.
CARACTÉRISTIQUES DE DÉPÔT DES BIOAÉROSOLS PAR IMPACTION INERTIEL
Creators: name: U. SOYSAL
name: E. GÉHIN
name: F. MARTY
name: E. ALGRÉ
name: C. MOTZKUS
Publisher: name: Association Française d'Etudes et de Recherches sur les Aérosols (ASFERA)
Year: 2019
Subjects: subject: Bioaérosols
subject: caractéristiques de dépôt
subject: détection en temps réel
subject: microbalance
subject: systèmes microélectromécaniques (MEMS)
subject: Bioaerosols
subject: deposition characteristics
subject: Real-time detection
subject: Microbalance
subject: Microelectromechanical systems (MEMS)

description: Dans ce contexte, de multiples bio-impacteurs sous la forme de buses un étage rondes ont été conçues, fabriquées et caractérisées à partir de considérations classiques dans la conception des impacteurs. Ensuite, des aérosols et bio-aérosols de différentes origines et tailles ont été impactées sur du silicium (lisse) et du silicium nano-structuré pour évaluer les caractéristiques de déposition de ces aérosols sur de telles surfaces. Les résultats expérimentaux montrent que la taille des particules volatiles déterminent les caractéristiques de déposition par un procédé de rebond et de ré-entrainement (effet de rebond). L'efficacité de collecte dans la première zone d'impact a été estimée. Le silicium nano-structuré permet de réduire l'effet de rebond des particules micrométriques grâce à ses piliers pointus en cassant les particules en plus petits fragments ce qui a comme conséquence de confiner la déposition sous la buse. Cette déposition localisée peut facilement être alignée avec un micro-capteur. Ainsi cette étude suggère que les capteurs MEMS de masse inertielle sont adaptés pour la détection de particules de tailles micrométriques.
A hydrodynamic limit for chemotaxis in a given heterogeneous environment
Creators: name: Grosskinsky, Stefan
name: Marahrens, Daniel
name: Stevens, Angela
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: Cell Behavior (q-bio.CB)
subject: FOS: Mathematics
subject: FOS: Biological sciences

description: In this paper the first equation within a class of well known chemotaxis systems is derived as a hydrodynamic limit from a stochastic interacting many particle system on the lattice. The cells are assumed to interact with attractive chemical molecules on a finite number of lattice sites, but they only directly interact among themselves on the same lattice site. The chemical environment is assumed to be stationary with a slowly varying mean, which results in a non-trivial macroscopic chemotaxis equation for the cells. Methodologically the limiting procedure and its proofs are based on results by Koukkus [18] and Kipnis/Landim [17]. Numerical simulations extend and illustrate the theoretical findings.
description: 21 pages, 16 figures
The design and synthesis of new synthetic low-molecular-weight heparins
Creators: name: Chandarajoti,
name: Pawlinski,
name: Liu,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Low molecular weight heparins (LMWH) have remained the most favorable form of heparin in clinics since 1990s’ owing to its predictable pharmacokinetic properties. However, LMWH is mainly eliminated through kidney, thus limits its use in renal-impaired patients. In addition, the anticoagulant activity of LMWH is only partially neutralized by protamine. LMWH is obtained from a full-length, highly sulfated polysaccharide harvested from porcine mucosal tissue. The depolymerization involved in LMWH production generates a broad size distribution of LMWH fragments (6-22 sugar residues). This, combined with the various methods used to produce commercial LMWHs, result in variable pharmacological and pharmacokinetic properties. An alternative, chemoenzymatic approach offers a method for the synthesis of LMWH that has the potential to overcome the limitations of current LMWHs. This review summarizes the application of a chemoenzymatic approach to generate LMWH and the rationale for development of a synthetic LMWH.
Mental health work in schools: How to educate children about mental health literacy? A mapping review of intervention components and implementation factors.
Creators: name: Tronvik, Hanne
name: Dahlgren, Astrid
Publisher: name: Zenodo
Year: 2022
Subjects: Mental health
Mental health literacy
Mapping review

description: Students project for the Masters degree in mental health. The purpose of this study is to explore components in mental health literacy interventions targeting school children about mental health literacy. A secondary objective is to analyze barriers and facilitators to implementation of such strategies. This will provide mental health professionals, teachers, policy makers and researchers with important background knowledge when considering implementing mental health literacy interventions in schools or when initiating new research efforts.
REMISE EN SUSPENSION DE PARTICULES DEPUIS DES SURFACES RUGUEUSES DANS DES PLASMAS STABLES DE TOKAMAKS
Creators: name: A. AUTRICQUE
name: S. PEILLON
name: F. GENSDARMES
name: M. SOW
name: N. FEDORCZAK
name: O. PLUCHERY
name: C. GRISOLIA
Publisher: name: Association Française d'Etudes et de Recherches sur les Aérosols (ASFERA)
Year: 2019
Subjects: subject: Poussières
subject: Tokamaks
subject: fusion
subject: remise en suspension
subject: Dust
subject: tokamaks
subject: fusion
subject: remobilization

description: Dans cette étude, la possibilité pour des particules de tungstène (W) d'être remobilisés depuis des surfaces face au plasma de tokamaks est examinée. Les distributions de forces d'adhésion entre des sphères de W de taille 1-10 µm et un substrat de W rugueux sont mesurées par microscope à force atomique. Nos résultats montrent que le modèle de Rabinovich reproduit de manière satisfaisante les mesures dans des intervalles de rugosité représentatifs des surfaces de tokamaks. Les forces extérieures (électrique et de friction des ions) sont estimées à l'aide d'un simple modèle de gaine électrostatique. Les résultats montrent que les poussières micrométriques peuvent être remises en suspension par des champs électriques atteignables dans les machines de fusion. Une estimation de la vitesse de ces particules en sortie de gaine révèle des vitesses de l'ordre de 0.1-1 m/s, dépendant des conditions plasma.
Tissue factor-positive tumor microvesicles activate platelets and enhance thrombosis in mice
Creators: name: Dee,
name: Fuentes,
name: Cooley,
name: Whelihan,
name: Geddings,
name: Mackman,
name: Hisada,
name: Wolberg,
name: Key,
name: Getz,
name: Bergmeier,
name: Boulaftali,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Cancer patients have an approximately four-fold increased risk of venous thromboembolism (VTE) compared with the general population, and cancer patients with VTE have reduced survival. Tumor cells constitutively release small membrane vesicles called microvesicles (MVs) that may contribute to thrombosis in cancer patients. Clinical studies have shown that levels of circulating tumor-derived, tissue factor-positive (TF+) MVs in pancreatic cancer patients are associated with VTE.
Fermi surface versus Fermi sea contributions to intrinsic anomalous and spin Hall effects of multiorbital metals in the presence of Coulomb interaction and spin-Coulomb drag
Creators: name: Arakawa, Naoya
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Anomalous Hall effect (AHE) and spin Hall effect (SHE) are fundamental phenomena, and their potential for application is great. However, we understand the interaction effects unsatisfactorily, and should have clarified issues about the roles of the Fermi sea term and Fermi surface term of the conductivity of the intrinsic AHE or SHE of an interacting multiorbital metal and about the effects of spin-Coulomb drag on the intrinsic SHE. Here we resolve the first issue and provide the first step about the second issue by developing a general formalism in the linear response theory with appropriate approximations and using analytic arguments. The most striking result is that even without impurities the Fermi surface term, a non-Berry-curvature term, plays dominant roles at high or slightly low temperatures. In particular, this Fermi surface term causes the temperature dependence of the dc anomalous Hall or spin Hall conductivity due to the interaction-induced quasiparticle damping and the correction of the dc spin Hall conductivity due to the spin-Coulomb drag. Those results revise our understanding of the intrinsic AHE and SHE. We also find that the differences between the dc anomalous Hall and longitudinal conductivities arise from the difference in the dominant multiband excitations. This not only explains why the Fermi sea term such as the Berry-curvature term becomes important in clean and low-temperature case only for interband transports but also provides the useful principles on treating the electron-electron interaction in an interacting multiorbital metal for general formalism of transport coefficients. Several correspondences between our results and experiments are finally discussed.
description: 23 pages 4 figure; published version
Additional file 1 of Silicon enhances the drought resistance of peach seedlings by regulating hormone, amino acid, and sugar metabolism
Creators: name: Gao, Huaifeng
name: Yu, Wenying
name: Yang, Xiaoqing
name: Liang, Jiahui
name: Sun, Xiwu
name: Sun, Maoxiang
name: Xiao, Yuansong
name: Peng, Futian
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 1: Table S1. Mapping statistics of the RNA-Seq data for three replicates in each treatment. Table S2. DEGs involved in ROS scavenging. Table S3. DEGs involved in hormone signal transduction. Table S4. DEGs involved in amino acids metabolism. Table S5. DEGs involved in starch and sucrose metabolism.
Selaginella erythropus Spring
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Lycopodiopsida
Selaginellales
Selaginellaceae
Selaginella
Selaginella erythropus

description: Selaginella erythropus (Mart.) Spring, in Martius, Fl. Bras. 1(2): 125. 1840.
 Range: — Costa Rica; Colombia to Bolivia (BE, CO, LP, SC); central and eastern Brazil.
 Ecology: —Common; terrestrial on moist riverbanks, steep, wet road banks, and in humid forests, sometimes forming dense colonies; to 1000 m.
 Notes: —Among the erect-stemmed species from Bolivia, only this and Selaginella haematodes have red stems. Selaginella erythropus is a smaller plant than S. haematodes, with more irregularly arranged branches.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. III. Selaginellaceae, pp. 248-258 in Phytotaxa 344 (3) on page 253, DOI: 10.11646/phytotaxa.344.3.5, http://zenodo.org/record/13719508
title: Tocilizumab als Mono- und Kombinationstherapie bei DMARDs-vorbehandelten Patienten
Creators: name: Behrens, Frank
name: Alberding, Annette
name: Biewer, Werner A.
name: Burmester, Gerd-Rüdiger
name: Feuchtenberger, Martin
name: Hofmann, Michael W.
name: Kästner, Peter
name: Kellner, Herbert
name: Kühne, Cornelia
name: Schmitz-Weckauf, Stephanie
name: Tony, Hans-Peter
name: Amberger, Christopher
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die nichtinterventionelle Studie ARATA (NCT02251860) untersucht die Effektivität einer subkutanen Tocilizumab-Therapie (RoACTEMRA®, TCZ) bei Patienten mit rheumatoider Arthritis unter Routinebedingungen. In dieser Interimsanalyse wurden Patienten nach ihrer Vortherapie und Begleittherapie[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: Einfluss der Kombinationstherapie von Rituximab und Lefluonmid auf Patient-Reported Outcomes und Funktion in Patienten mit Rheumatoider Arthritis: Ergebnisse einer multizentrischen, randomisierten, Placebo-kontrollierten Investigator initiierten Studie (AMARA-Study)
Creators: name: Köhm, Michaela
name: Rossmanith, Tanja
name: Dauth, Stephanie
name: Alten, Rieke H.-E.
name: Aringer, Martin
name: Backhaus, Marina
name: Burmester, Gerd-Rüdiger
name: Feist, Eugen
name: Kellner, Herbert
name: Krüger, Klaus
name: Müller-Ladner, Ulf
name: Rubbert-Roth, Andrea
name: Tony, Hans-Peter
name: Wassenberg, Siegfried
name: Burkhardt, Harald Louis
name: Behrens, Frank
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Biologikatherapien wie Rituximab (RTX) stellen eine wirksame Therapieoption in der Behandlung der Rheumatoiden Arthritis (RA) dar. Zumeist sind hier ausschließlich Kombinationstherapien mit Methotrexat (MTX) zugelassen, obwohl bei Kontraindikationen oder Unverträglichkeiten andere[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: Retentionsraten für Etanercept: Vergleich des Originals mit einem Biosimilar
Creators: name: Strangfeld, Anja
name: Baganz, Lisa
name: Herzer, Peter
name: Braun, Jürgen
name: Gräßler, Anett
name: Zink, Angela
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Seit der Erstzulassung eines Biosimilars in der Rheumatologie im Jahr 2015 werden Patienten mit rheumatoider Arthritis (RA) immer häufiger mit diesen Substanzen behandelt. Bislang gibt es nur wenige Analysen, die den Therapieverbleib auf Biosimilars den jeweiligen Originalpräparaten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: Verteilung der ß2-adrenergen Rezeptor Polymorphismen bei Patienten mit entzündlich-rheumatischen Erkrankungen und Arteriosklerose
Creators: name: Wirtz, Helen
name: Seifert, Olga
name: Barghan, Helen
name: Baerwald, Christoph G. O.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Arteriosklerose (AS) steht als häufigste Todesursache im Rahmen von Herz-Kreislauf-Erkrankungen im besonderen Fokus der medizinischen Forschung. Die AS ist eine Erkrankung mit unklarer Ätiologie, die von einer besonderen genetischen Disposition und einer Vielzahl verschiedener[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: Fatty lesions detected on MRI scans in patients with ankylosing spondylitis are based on the deposition of fat in the vertebral bone marrow
Creators: name: Baraliakos, Xenofon
name: Böhm, Heinrich
name: Samir, Ahmed
name: Schett, Georg
name: Braun, Jürgen
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Fatty lesions (FL), similar to bone marrow edema (BME) and sclerosis (SCL), are characteristic findings in MRI examinations of patients with ankylosing spondylitis (AS) and degenerative disc disease (DDD). It has recently been shown that FL are associated with syndesmophyte formation in [for full text, please go to the a.m. URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury
Creators: name: Knapp,
name: Hell,
name: Horvath,
name: Ay,
name: Schmid,
name: Assinger,
name: Niederreiter,
name: Kral-Pointner,
name: Mackman,
name: Jilma,
name: Datler,
name: Schabbauer,
name: Schrottmaier,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Essentials Tissue factor (TF) represents a central link between hemostasis and inflammation. We studied the roles of myeloid and airway epithelial TF in acid-caused acute lung injury (ALI). TF on myeloid cells displays a non-coagulatory role regulating the inflammatory response in ALI. Airway epithelial TF contributes to hemostatic functions, but is dispensable in ALI pathogenesis.

SUMMARY: Introduction Acute lung injury (ALI) is a life-threatening condition characterized by damaged alveolar-capillary structures and activation of inflammatory and hemostatic processes. Tissue factor (TF) represents a crucial link between inflammation and coagulation, as inflammatory mediators induce myeloid TF expression, and TF initiates extrinsic coagulation. Objective As pulmonary inflammation stimulates TF expression and TF modulates immune responses, we aimed to elucidate its impact on ALI. In particular, we wanted to distinguish the contributions of TF expressed on airway epithelial cells and TF expressed on myeloid cells. Methods Mice with different cell type-specific TF deficiency and wild-type littermates were intratracheally treated with hydrochloric acid, and leukocyte recruitment, cytokine levels, thrombin-antithrombin (TAT) complexes and pulmonary protein-rich infiltrates were analyzed. Results Our data demonstrate that a lack of epithelial TF did not influence acute responses, as bronchoalveolar neutrophil accumulation 8 h after ALI induction was unaltered. However, it led to mild, prolonged inflammation, as pulmonary leukocyte and erythrocyte numbers were still increased after 24 h, whereas those in wild-type mice had returned to basal levels. In contrast, myeloid TF was primarily involved in regulating the acute phase of ALI without affecting local coagulation, as indicated by increased bronchoalveolar neutrophil infiltration, pulmonary interleukin-6 levels, and edema formation, but equal TAT complex formation, 8 h after ALI induction. This augmented inflammatory response associated with myeloid TF deficiency was confirmed in vitro, as lipopolysaccharide-stimulated TF-deficient alveolar macrophages released increased levels of chemokine (C-X-C motif) ligand 1 and tumor necrosis factor-α as compared with wild-type macrophages. Conclusion We conclude that myeloid TF dampens inflammation in acid-induced ALI.
Additional file 1 of Implementing surgical mentorship in a resource-constrained context: a mixed methods assessment of the experiences of mentees, mentors, and leaders, and lessons learned
Creators: name: Alidina, Shehnaz
name: Sydlowski, Meaghan M.
name: Ahearn, Olivia
name: Andualem, Bizuayehu G.
name: Barash, David
name: Bari, Sehrish
name: Barringer, Erin
name: Bekele, Abebe
name: Beyene, Andualem D.
name: Burssa, Daniel G.
name: Derbew, Miliard
name: Drown, Laura
name: Gulilat, Dereje
name: Gultie, Teruwork K.
name: Hayirli, Tuna C.
name: Meara, John G.
name: Staffa, Steven J.
name: Workineh, Samson E.
name: Zanial, Noor
name: Zeleke, Zebenay B.
name: Mengistu, Abraham E.
name: Ashengo, Tigistu A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Ethiopia mentorship survey.
title: Prevalence of inflammatory and chronic changes suggestive of axial spondyloarthritis in magnetic resonance images of the axial skeleton in individuals <45 years in the general population as part of a large community study (SHIP)
Creators: name: Baraliakos, Xenofon
name: Feldmann, Daniel
name: Anne, Ott
name: Schmidt, Carsten Oliver
name: Albers, Martin
name: Richter, Adrian
name: Braun, Jürgen
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Magnetic resonance imaging (MRI) is crucial for classification and diagnosis of axial spondyloarthritis (axSpA). Characteristic MRI lesions of axSpA are bone marrow edema (BME) or structural fatty lesions (FL) of the sacroiliac joints (SIJ) and spine. However, the specificity of these lesions[for full text, please go to the a.m. URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
MODERATED MEDIATION MODEL: FACTORS THAT AFFECT BRAND LOYALTY IN MEDICAL AESTHETIC CLINICS IN THAILAND
Creators: name: Phacharaporn PHIJARANAKUL
Publisher: name: Asian Administration and Management Review
Year: 2022
Subjects: Online Brand Community
Brand Awareness
Brand Image
Brand Trust
Brand Loyalty

description: Asian Administration and Management Review, 5, 2, 141-154
Standardization of microparticle enumeration across different flow cytometry platforms: results of a multicenter collaborative workshop
Creators: name: Key,
name: Judicone,
name: Poncelet,
name: Dignat-George,
name: Lacroix,
name: Mooberry,
name: Nieuwland,
name: Cointe,
name: Robert,
name: Wauben,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Microparticles are extracellular vesicles resulting from the budding of cellular membranes that have a high potential as emergent biomarkers; however, their clinical relevance is hampered by methodological enumeration concerns and a lack of standardization. Flow cytometry (FCM) remains the most commonly used technique with the best capability to determine the cellular origin of single MPs. However, instruments behave variably depending on which scatter parameter, (Forward (FSC) or Side scatter (SSC)), provides the best resolution to discriminate submicron particles. To overcome this problem, a new approach, based on two sets of selected beads adapted to FSC or SSC optimized instruments, was recently proposed to reproducibly enumerate platelet-derived MP counts among instruments with different optical systems.
Additional file 2 of Implementing surgical mentorship in a resource-constrained context: a mixed methods assessment of the experiences of mentees, mentors, and leaders, and lessons learned
Creators: name: Alidina, Shehnaz
name: Sydlowski, Meaghan M.
name: Ahearn, Olivia
name: Andualem, Bizuayehu G.
name: Barash, David
name: Bari, Sehrish
name: Barringer, Erin
name: Bekele, Abebe
name: Beyene, Andualem D.
name: Burssa, Daniel G.
name: Derbew, Miliard
name: Drown, Laura
name: Gulilat, Dereje
name: Gultie, Teruwork K.
name: Hayirli, Tuna C.
name: Meara, John G.
name: Staffa, Steven J.
name: Workineh, Samson E.
name: Zanial, Noor
name: Zeleke, Zebenay B.
name: Mengistu, Abraham E.
name: Ashengo, Tigistu A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. Interview protocols.
title: Real-World-Daten zur Verwendung von Certolizumab Pegol bei axialer Spondyloarthritis in der klinischen Praxis in Europa: 24-Wochen-Ergebnisse einer prospektiven, nicht-interventionellen Kohortenstudie
Creators: name: Baraliakos, Xenofon
name: Goodson, Nicola
name: Witte, Torsten
name: De Clerk, Luc
name: Galeazzi, Mauro
name: Collantes-Estévez, Eduardo
name: Kumke, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Certolizumab Pegol (CZP) ist ein PEGylierter, Fc-freier Anti-TNF mit dokumentierter Wirksamkeit und Sicherheit bei axialer Spondyloarthritis (axSpA). Diese multizentrische, prospektive Kohortenstudie befasst sich erstmals mit der Verträglichkeit und Effektivität von CZP in der [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Pointwise Bounds and Blow-up for Nonlinear Polyharmonic Inequalities
Creators: name: Taliaferro, Steven D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35B09, 35B33, 35B40, 35B44, 35B45, 35R45, 35J30, 35J91

description: We obtain results for the following question where $m\ge 1$ and $n\ge 2$ are integers. Question. For which continuous functions $f\colon [0,\infty)\to [0,\infty)$ does there exist a continuous function $φ\colon (0,1)\to (0,\infty)$ such that every $C^{2m}$ nonnegative solution $u(x)$ of $ 0 \le -Δ^m u\le f(u)\quad$ in $B_2(0)\setminus\{0\}\subset {\bf R}^n $ satisfies $u(x) = O(φ(|x|))\quad \text{as } x\to 0 $ and what is the optimal such $φ$ when one exists?
description: 32 pages. This is a much-improved version of "Isolated Singularities of Nonlinear Polyharmonic Inequalities" arXiv:1107.4586
Selaginella exaltata Spring, Bull. Acad. Roy. Sci. Bruxelles
Creators: name: Smith, Alan R.
name: Kessler, Michael
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Lycopodiopsida
Selaginellales
Selaginellaceae
Selaginella
Selaginella exaltata

description: Selaginella exaltata (Kunze) Spring, Bull. Acad. Roy. Sci. Bruxelles 10: 234. 1843.
 Range: — Costa Rica to Bolivia (PA) and northern Brazil.
 Ecology: —Common; scrambling in humid forests, mostly along forest borders and in disturbed or secondary vegetation; to 300 m.
 Notes: —Unmistakable climbing or scrambling species reaching up to 3(–8) m tall, with tripinnate, frond-like, pubescent branches. This species, along with a few other close relatives, may be allied to the other articulate species, and may have an isolated position within the family (Zhou et al. 2015; Weststrand & Korall 2016a). Results of recent molecular work are somewhat conflicting, and additional sampling of seemingly related species needs to be conducted.
description: Published as part of Smith, Alan R. & Kessler, Michael, 2018, Prodromus of a fern flora for Bolivia. III. Selaginellaceae, pp. 248-258 in Phytotaxa 344 (3) on page 253, DOI: 10.11646/phytotaxa.344.3.5, http://zenodo.org/record/13719508
Guidance for the evaluation and treatment of hereditary and acquired thrombophilia
Creators: name: Streiff, Michael
name: Douketis, James D.
name: Cushman, Mary
name: Lim, Wendy
name: Kasthuri, Raj
name: Bauer, Kenneth A.
name: Woller, Scott C.
name: Stevens, Scott M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Thrombophilias are hereditary and/or acquired conditions that predispose patients to thrombosis. Testing for thrombophilia is commonly performed in patients with venous thrombosis and their relatives; however such testing usually does not provide information that impacts management and may result in harm. This manuscript, initiated by the Anticoagulation Forum, provides clinical guidance for thrombophilia testing in five clinical situations: following 1) provoked venous thromboembolism, 2) unprovoked venous thromboembolism; 3) in relatives of patients with thrombosis, 4) in female relatives of patients with thrombosis considering estrogen use; and 5) in female relatives of patients with thrombosis who are considering pregnancy. Additionally, guidance is provided regarding the timing of thrombophilia testing. The role of thrombophilia testing in arterial thrombosis and for evaluation of recurrent pregnancy loss is not addressed. Statements are based on existing guidelines and consensus expert opinion where guidelines are lacking. We recommend that thrombophilia testing not be performed in most situations. When performed, it should be used in a highly selective manner, and only in circumstances where the information obtained will influence a decision important to the patient, and outweigh the potential risks of testing. Testing should not be performed during acute thrombosis or during the initial (3-month) period of anticoagulation.
Is the CMS eejj excess a hint for light supersymmetry?
Creators: name: Krauss, Manuel E.
name: Porod, Werner
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We discuss the impact of additional two-body decays of the right-handed neutrino into a light charged Higgs state on the dilepton plus dijet cross sections from resonant $W'$ production. We consider in particular a supersymmetric left-right symmetric model which predicts such a light charged Higgs boson. We demonstrate that the $eejj$ excess as measured by CMS can be explained best if the $W'$ also has decay modes into Higgsino-like charginos and neutralinos with masses of a few hundred GeV. Provided that this excess is confirmed, the model predicts also one right-handed neutrino with a mass below 200 GeV as well as a doubly charged Higgs boson which should be discovered at the LHC in the near future.
description: 8 pages, 4 figures; v2: minor changes, references added; matches published version
Jahresbericht 2017: Data Center for the Humanities, Philosophische Fakultät der Universität zu Köln
Creators: name: Blumtritt, Jonathan
name: Helling, Patrick
name: Metzmacher, Katja
Publisher: name: Zenodo
Year: 2018
Subjects: Data Center for the Humanities
DCH
Universität zu Köln
Jahresbericht 2017
Forschungsdatenmanagement
FDM

description: Jahresbericht 2017 des Data Center for the Humanities, Philosophische Fakultät der Universität zu Köln
title: Welche Faktoren beeinflussen die Diagnoseverzögerung bei Personen mit axialer Spondyloarthritis?
Creators: name: Redeker, Imke
name: Callhoff, Johanna
name: Hoffmann, Falk
name: Haibel, Hildrun
name: Sieper, Joachim
name: Zink, Angela
name: Poddubnyy, Denis
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die Zeitdauer zwischen Symptombeginn und Diagnosestellung ist bei axialer Spondyloarthritis (axSpA) mit fünf bis zehn Jahren die längste unter den rheumatischen Erkrankungen. Das Ziel dieser Analyse war es zu untersuchen, ob sich die Diagnoseverzögerung innerhalb der letzten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
A coupling approach to Doob’s theorem
Creators: name: Kulik, Alexei
name: Scheutzow, Michael
Publisher: name: Technische Universität Berlin
Year: 2015
Subjects: subject: 510 Mathematik
subject: Markov process
subject: invariant measure
subject: coupling
subject: convergence of transition probabilities
subject: total variation distance

description: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
description: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
description: We provide a coupling proof of Doob’s theorem which says that the transition probabilities of a regular Markov process which has an invariant probability measure μ converge to μ in the total variation distance. In addition we show that non-singularity (rather than equivalence) of the transition probabilities suffices to ensure convergence of the transition probabilities for μ-almost all initial conditions.
DOMESTIC STATUS OF WOMEN IN RELATION TO EDUCATION AND OFFENCE
Creators: name: Miss. DARSHANA R. CHAVDA1   Dr. RAVI DHANANI2
Publisher: name: Zenodo
Year: 2022

description: Introduction: Evolutionary history of mankind clearly demonstrates the fact that women in general appear to be understood in the society. Society in general appears to have not given due weightage to women in respect to human development quantitatively and qualitatively it is found that women have met illtreatment at large. There is of course considerable degree of variation found across the countries of the world with respect to domestic status of women. Historically looking back at the classical cultural history of India we find plenty of apprecinting examples where in women were considered as most instrumental one for sociocultural upgradation of the society. Even today ancient India's characteristict in the form of revenue for women to quote from Sanskrit verse, There are also leading women found in Pre Independence period who have through their valour and vibrancy contributed richly to Indian Society. To name such as Chandbibi, Viranga Laxmibai or In 20th Century toll independence. We have illustrious examples of Annie Bessent, Kas Turbal Sanrojini Naydu whose works are inspirational for women even today. Despite all these it is of crucial significance to note that maximum ailment, torture, dis respect women suffered in medieval age globally John Sturt Mill is considered as pioneer in respect of Women's lib. Late Maithilisharan Gupta a legendary nationalist Hindi poet very critically wrote that. True it is that there is found considerable degree of improvement in the domestic of women under Post Independent India. India is an exceptional nation to have credited women with right to franchise right from 1951's first general election. Under Article 14 of constitution of India "Equality before the law without any sirt of discrimination is assured to all citizens. There is also made Women's respresentation mandatory one in all type of local Govt. bodies. With many other legal provisions and gender related wel fare mechanism being applied "Domestic Status" of women is still considered "Below to Average"
On form factors of boundary changing operators
Creators: name: Bajnok, Zoltan
name: Hollo, Laszlo
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We develop a form factor bootstrap program to determine the matrix elements of local, boundary condition changing operators. We propose axioms for these form factors and determine their solutions in the free boson and Lee-Yang models. The sudden change in the boundary condition, caused by an operator insertion, can be interpreted as a local quench and the form factors provide the overlap of any state before the quench with any outgoing state after the quench.
description: 34 pages, v3: comparison to relevant works of Lesage and Saleur are added
Guidance for the treatment of deep vein thrombosis and pulmonary embolism
Creators: name: Agnelli, Giancarlo
name: Crowther, Mark
name: Ansell, Jack
name: McBane, Robert D.
name: Eichinger, Sabine
name: Streiff, Michael B.
name: Connors, Jean M.
name: Lopes, Renato
name: Moll, Stephan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: This guidance document focuses on the diagnosis and treatment of venous thromboembolism (VTE). Efficient, cost effective diagnosis of VTE is facilitated by combining medical history and physical examination with pre-test probability models, D dimer testing and selective use of confirmatory imaging. Clinical prediction rules, biomarkers and imaging can be used to tailor therapy to disease severity. Anticoagulation options for acute VTE include unfractionated heparin, low molecular weight heparin, fondaparinux and the direct oral anticoagulants (DOACs). DOACs are as effective as conventional therapy with LMWH and vitamin K antagonists. Thrombolytic therapy is reserved for massive pulmonary embolism (PE) or extensive deep vein thrombosis (DVT). Inferior vena cava filters are reserved for patients with acute VTE and contraindications to anticoagulation. Retrievable filters are strongly preferred. The possibility of thoracic outlet syndrome and May-Thurner syndrome should be considered in patients with subclavian/axillary and left common iliac vein DVT, respectively in absence of identifiable triggers. The optimal duration of therapy is dictated by the presence of modifiable thrombotic risk factors. Long term anticoagulation should be considered in patients with unprovoked VTE as well as persistent prothrombotic risk factors such as cancer. Short-term therapy is sufficient for most patients with VTE associated with transient situational triggers such as major surgery. Biomarkers such as D dimer and risk assessment models such the Vienna risk prediction model offer the potential to customize VTE therapy for the individual patient. Insufficient data exist to support the integration of bleeding risk models into duration of therapy planning.
Additional file 3 of Implementing surgical mentorship in a resource-constrained context: a mixed methods assessment of the experiences of mentees, mentors, and leaders, and lessons learned
Creators: name: Alidina, Shehnaz
name: Sydlowski, Meaghan M.
name: Ahearn, Olivia
name: Andualem, Bizuayehu G.
name: Barash, David
name: Bari, Sehrish
name: Barringer, Erin
name: Bekele, Abebe
name: Beyene, Andualem D.
name: Burssa, Daniel G.
name: Derbew, Miliard
name: Drown, Laura
name: Gulilat, Dereje
name: Gultie, Teruwork K.
name: Hayirli, Tuna C.
name: Meara, John G.
name: Staffa, Steven J.
name: Workineh, Samson E.
name: Zanial, Noor
name: Zeleke, Zebenay B.
name: Mengistu, Abraham E.
name: Ashengo, Tigistu A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3. Mentor and mentoring relationships and characteristics.
title: УНИВЕРСИТЕТ В РЕГИОНАЛЬНОЙ ИННОВАЦИОННОЙ СИСТЕМЕ КАК ЭЛЕМЕНТЕ СТРУКТУРЫ СИСТЕМЫ МЕНЕДЖМЕНТА МЕЖДУНАРОДНОГО ТРАНСПОРТНОГО КОРИДОРА
title: Статья
titleType: Subtitle
Creators: name: Мартынов, Б.В.
Publisher: name: "Южный Университет (ИУБиП)"
Year: 2018
Subjects: международный транспортный коридор
система менеджмента
цифровая экономика

Abstract