cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplemental Material, pham.app2.rev - Short Take: Lowering the Access Barriers to Ethnographic Methodology
Creators: name: Pham, Tony V
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental Material, pham.app2.rev for Short Take: Lowering the Access Barriers to Ethnographic Methodology by Tony V Pham in Field Methods
Coverage of Aboriginal and Torres Strait Islander nutrition in the Koori Mail
Creators: name: Ares, Maria Vargas
name: Browne, Jennifer
name: T Hardy
name: E Moore
name: Vally, Hassan
name: Gleeson, Deborah
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Authors Objective: To examine the extent and nature of coverage of nutrition in the Koori Mail. Methods: Content and framing analysis were used to examine articles in the Koori Mail published between 2013 and 2017 that included the terms ‘nutrition∗’, ‘diet∗’, ‘food’, ‘eating’, ‘weight’, ‘tucker’ or ‘sugary drinks’. The analysis focused on the portrayal of Aboriginal and Torres Strait Islander people/communities, inclusion of First Peoples’ voices and the framing of nutrition issues. Results: A total of 102 articles were included. Most articles (88%, n=90) portrayed Aboriginal and Torres Strait Islander communities in a neutral or positive way and more than half (53%, n=54) included an Aboriginal or Torres Strait Islander voice. While nutrition was often framed as an individual or community responsibility, articles predominantly promoted programs or initiatives undertaken in local communities. Conclusion: Despite the limited prominence of Aboriginal and Torres Strait Islander nutrition in the mainstream media, the coverage of nutrition issues in the Koori Mail demonstrates the salience of this topic for local communities. This study highlights how journalism can better reflect the diversity and strengths of First Peoples. Implications for public health: Including more Aboriginal and Torres Strait Islander voices and using a strengths-based approach in press releases may improve media advocacy.
Additional file 1 of Physical discipline as a normative childhood experience in Singapore
Creators: name: Sudo, Mioko
name: Won, Ying Qing
name: Chau, Winnie W. Y.
name: Meaney, Michael J.
name: Kee, Michelle Z. L
name: Chen, Helen
name: Eriksson, Johan Gunnar
name: Yap, Fabian
name: Rifkin-Graboi, Anne
name: Tiemeier, Henning
name: Setoh, Peipei
Publisher: name: figshare
Year: 2024
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Contingency Table for Frequency at Which Children Were Physically Punished by Their Mothers as Reported by Their Mothers and Fathers. Table S2. Contingency Table for Frequency at Which Children Were Physically Punished by Their Fathers as Reported by Their Fathers and Mothers. Table S3. Contingency Table for Frequency at Which Children Were Spanked by Their Mothers as Reported by Their Mothers and Fathers. Table S4. Contingency Table for Frequency at Which Children Were Spanked by Their Fathers as Reported by Their Fathers and Mothers. Table S5. Contingency Table for Frequency at Which Children Were Slapped by Their Mothers as Reported by Their Mothers and Fathers. Table S6. Contingency Table for Frequency at Which Children Were Slapped by Their Fathers as Reported by Their Fathers and Mothers. Table S7. Contingency Table for Frequency at Which Children Were Grabbed by Their Mothers as Reported by Their Mothers and Fathers. Table S8. Contingency Table for Frequency at Which Children Were Grabbed by Their Fathers as Reported by Their Fathers and Mothers. Table S9. Prevalence of Physical Discipline of Children by Their Parents at Age 4.5, 6, 9, and 11 According to Child Sex. Table S10. Prevalence of Physical Discipline of Children by Their Mothers and Fathers at Age 9. Table S11. Prevalence of Physical Discipline of Children by Their Mothers at Age 4.5, 6, 9, and 11 by Maternal Ethnicity.
_online_supp_-_Supplementary_Information_file_Geise_et_al_2020 – Supplemental material for Still Images—Moving People? How Media Images of Protest Issues and Movements Influence Participatory Intentions
Creators: name: Geise, Stephanie
name: Panke, Diana
name: Heck, Axel
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, _online_supp_-_Supplementary_Information_file_Geise_et_al_2020 for Still Images—Moving People? How Media Images of Protest Issues and Movements Influence Participatory Intentions by Stephanie Geise, Diana Panke and Axel Heck in The International Journal of Press/Politics
Microvesicles and exosomes isolated from murine bone marrow-derived mesenchymal stromal cells primed with p38MAPK inhibitor differentially regulate hematopoietic stem cell function
Creators: name: Budgude, Pallavi
name: Kale, Vaijayanti
name: Vaidya, Anuradha
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: The signaling mechanisms active within mesenchymal stromal cells (MSCs) influence the composition of microvesicles (MVs) and exosomes (Exos) secreted by them. Previously, we showed that priming MSCs with a p38 pharmacological inhibitor (pMSCs) rejuvenates them and improves their ability to promote ex vivo hematopoietic stem cell (HSC) expansion. This study examined whether pMSCs exerted HSC-supportive ability via MVs (pMVs) and Exos (pExos). Our findings demonstrate distinct regulation of HSC fate by pMVs and pExos. pMVs promoted the expansion of long-term HSCs (LT-HSCs), distinguished by their robust self-renewal capacity and superior engraftment ability. In contrast, pExos facilitated expansion of short-term HSCs (ST-HSCs) with high proliferative and differentiation potential. Infusing a combination of pMVs- and pExos-expanded HSCs as a composite graft resulted in significantly higher HSC engraftment, emphasizing the synergistic interaction between LT- and ST-HSC populations. Gene expression studies, functional and phenotypic experiments showed that pMVs regulate HSC quiescence via the Egr1/Cdkn1a axis, while pExos control HSC proliferation via the Nfya/Cdkn1a axis. These findings provide insights into the molecular mechanisms underlying the differential regulation of HSC function by pMVs and pExos. It also proposes a composite graft strategy of using pMVs and pExos as “MSC-derived biologics” for improving the HSC transplantation success.
Protein markers for Candida albicans EVs include claudin-like Sur7 family proteins
Creators: name: Dawson, Charlotte
name: Garcia-Ceron, Donovan
name: Kolin Rajapaksha
name: Faou, Pierre
name: Bleackley, Mark
name: Anderson, Marilyn
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Background: Fungal extracellular vesicles (EVs) have been implicated in host-pathogen and pathogen-pathogen communication in some fungal diseases. In depth research into fungal EVs has been hindered by the lack of specific protein markers such as those found in mammalian EVs that have enabled sophisticated isolation and analysis techniques. Despite their role in fungal EV biogenesis, ESCRT proteins such as Vps23 (Tsg101) and Bro1 (ALIX) are not present as fungal EV cargo. Furthermore, tetraspanin homologs are yet to be identified in many fungi including the model yeast S. cerevisiae. Objective: We performed de novo identification of EV protein markers for the major human fungal pathogen Candida albicans with adherence to MISEV2018 guidelines. Materials and methods: EVs were isolated by differential ultracentrifugation from DAY286, ATCC90028 and ATCC10231 yeast cells, as well as DAY286 biofilms. Whole cell lysates (WCL) were also obtained from the EV-releasing cells. Label-free quantitative proteomics was performed to determine the set of proteins consistently enriched in EVs compared to WCL. Results: 47 proteins were consistently enriched in C. albicans EVs. We refined these to 22 putative C. albicans EV protein markers including the claudin-like Sur7 family (Pfam: PF06687) proteins Sur7 and Evp1 (orf19.6741). A complementary set of 62 EV depleted proteins was selected as potential negative markers. Conclusions: The marker proteins for C. albicans EVs identified in this study will be useful tools for studies on EV biogenesis and cargo loading in C. albicans and potentially other fungal species and will also assist in elucidating the role of EVs in C. albicans pathogenesis. Many of the proteins identified as putative markers are fungal specific proteins indicating that the pathways of EV biogenesis and cargo loading may be specific to fungi, and that assumptions made based on studies in mammalian cells could be misleading. Abbreviations: A1–ATCC10231; A9–ATCC90028; DAY B–DAY286 biofilm; DAY Y–DAY286 yeast; EV–extracellular vesicle; Evp1–extracellular vesicle protein 1 (orf19.6741); GO–gene ontology; Log2(FC)–log2(fold change); MCC–membrane compartment of Can1; MDS–multidimensional scaling; MISEV–minimal information for studies of EVs; sEVs–small EVs; SP–signal peptide; TEMs–tetraspanin enriched microdomains; TM–transmembrane; VDM–vesicle-depleted medium; WCL–whole cell lysate.
Implementing 'Science Up Close': an innovative researcher-curated exhibition at the Florida Museum of Natural History
Creators: name: Narducci, Rachel
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference oral presentation on Implementing 'Science Up Close': an innovative researcher-curated exhibition at the Florida Museum of Natural History by Natural History Lab Coordinator Rachel Narducci of Natural History Lab Coordinator Florida Museum of Natural History GAINESVILLE United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Additional file 5 of The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells
Creators: name: Wu, Yi-Hui
name: Huang, Yu-Fang
name: Wu, Pei-Ying
name: Chang, Tzu-Hao
name: Huang, Soon-Cen
name: Chou, Cheng-Yang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Additional file 5: Table 2. The correlations between variables and M1 or M2 sites (n = 161).
Supplemental Material, R1_tables_092820_supp_material - Factors Associated with Lack of HIV Testing among Latino Immigrant and Black Patients at 4 Geographically and Demographically Diverse Emergency Departments
Creators: name: Bennett, Christopher L.
name: Marks, Sarah J.
name: Liu, Tao
name: Clark, Melissa A.
name: Carey, Michael P.
name: Merchant, Roland C.
Publisher: name: SAGE Journals
Year: 2020
Subjects: Health and Community Services
Aged Health Care
Public Health and Health Services not elsewhere classified

description: Supplemental Material, R1_tables_092820_supp_material for Factors Associated with Lack of HIV Testing among Latino Immigrant and Black Patients at 4 Geographically and Demographically Diverse Emergency Departments by Christopher L. Bennett, Sarah J. Marks, Tao Liu, Melissa A. Clark, Michael P. Carey and Roland C. Merchant in Journal of the International Association of Providers of AIDS Care (JIAPAC)
Antibacterial lipid liquid crystalline nanoparticles – synthesis and optimization by central composite design
Creators: name: Jagielski, Jakub
name: Dydak, Karolina
name: Jaskot, Kaja
name: Soloviov, Dmytro
name: Kozak, Maciej
name: Nowaczyk, Grzegorz
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: The rise of antibiotic-resistant bacteria demands new antimicrobial strategies. Glyceryl monolaurate (GML) shows antibacterial activity against Gram-positive bacteria like S. aureus but is ineffective against Gram-negative E. coli due to its outer membrane. GML’s limited solubility and susceptibility to bacterial lipases hinder its direct use. This study developed glyceryl monooleate (GMO) lipid liquid crystalline nanoparticles (LLCNPs) incorporating GML to enhance its stability and efficacy. Using a central composite design (CCD), an optimal GMO:GML:F127 mass ratio of 26.5:3.5:1.5 was achieved. Characterization via dynamic light scattering (DLS), small angle X-ray scattering (SAXS), and cryo-transmission electron microscopy (cryo-TEM) confirmed the formation of bicontinuous cubic phase nanoparticles (Pn3m space group) with hydrophobic, hydrophilic, and amphiphilic regions, enabling the incorporation of diverse agents and the presence of sponge-like nanoparticles. The optimized LLCNPs inhibited S. aureus growth at concentrations ≥10 µg/mL by disrupting its membrane potential but showed no activity against E. coli. Cytotoxicity studies indicated that GML incorporation did not significantly affect cell viability compared to pure GMO LLCNPs. This nanoparticle system offers a biocompatible solution for treating Gram-positive bacterial infections and may synergize with existing antibiotics, warranting further investigation into its mechanisms and therapeutic potential.
Evolution of sequence-diverse disordered regions in a protein family: order within the chaos
Creators: name: Shafee, Thomas
name: Bacic, Tony
name: Johnson, Kim
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. Approaches for studying the evolution of globular proteins are now well established yet are unsuitable for disordered sequences. Our understanding of the evolution of proteins containing disordered regions therefore lags that of globular proteins, limiting our capacity to estimate their evolutionary history, classify paralogs, and identify potential sequence-function relationships. Here, we overcome these limitations by using new analytical approaches that project representations of sequence space to dissect the evolution of proteins with both ordered and disordered regions, and the correlated changes between these. We use the fasciclin-like arabinogalactan proteins (FLAs) as a model family, since they contain a variable number of globular fasciclin domains as well as several distinct types of disordered regions: proline (Pro)-rich arabinogalactan (AG) regions and longer Pro-depleted regions. Sequence space projections of fasciclin domains from 2019 FLAs from 78 species identified distinct clusters corresponding to different types of fasciclin domains. Clusters can be similarly identified in the seemingly random Pro-rich AG and Pro-depleted disordered regions. Sequence features of the globular and disordered regions clearly correlate with one another, implying coevolution of these distinct regions, as well as with the N-linked and O-linked glycosylation motifs. We reconstruct the overall evolutionary history of the FLAs, annotated with the changing domain architectures, glycosylation motifs, number and length of AG regions, and disordered region sequence features. Mapping these features onto the functionally characterized FLAs therefore enables their sequence-function relationships to be interrogated. These findings will inform research on the abundant disordered regions in protein families from all kingdoms of life.
Supplemental_Table_3 – Supplemental material for Verbal Abuse Among Nurses Working in a Nepalese Government Hospital
Creators: name: Lamichhane, Anjana
name: Sung-Heui Bae
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Supplemental_Table_3 for Verbal Abuse Among Nurses Working in a Nepalese Government Hospital by Anjana Lamichhane and Sung-Heui Bae in Asia Pacific Journal of Public Health
OLIGOMERIZATION OF THE  ETHYLENE IN THE PRESENCE  OF NEW HETEROGENIZED  Zr-CONTAINING COMPLEX CATALYTIC SYSTEMS
Creators: name: Azizov, Akif Hamid
name: Khamiyev, Matlab Jahangir
name: Khanmetov, Akber Akber
name: Aliyeva, Reyhan Valy
name: Aliyev, Bakir Mehbali
name: Ahmedbekova, Saida Fuad
Publisher: name: European Chemical Bulletin
Year: 2015

description: The new heterogenized zirconium phenolate complexes containing different bulky ionic liquid type amine hydrochloride substituents in ortho-position have been synthesized and characterized. The oligomerization of the ethylene was carried out with use of these complexes activated by aluminum organic compounds in heptane, toluene and chlorobenzene. In the presence of diethyl aluminum chloride these complexes show higher activity than in the presence of ethylaluminum dichloride. The distributions and composition of the obtained oligomer products depend on the nature of aluminum organic compound used. The oligomerization products consist of C4 - C18 oligomers when diethyl aluminum chloride is used as a cocatalyst. In the presence of ethylaluminum dichloride the higher branched structured oligomers (oil fraction with boiling point > 350 °C) is obtained with >75 % yield. The products are easily separated from the catalysts by simple decantation and zirconium complexes may be repeatedly reused in successive ethylene oligomerization.
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
Supplementary Material 1 - Supplemental material for Clinical Outcomes Among Bullous Pemphigoid Patients—A Comparison of Urban and Rural Populations
Creators: name: MacGillivray, Megan E.
name: Navjeet Gill
name: Salopek, Thomas G.
name: Gniadecki, Robert
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental material, Supplementary Material 1, for Clinical Outcomes Among Bullous Pemphigoid Patients—A Comparison of Urban and Rural Populations by Megan E. MacGillivray, Navjeet Gill, Thomas G. Salopek and Robert Gniadecki in Journal of Cutaneous Medicine and Surgery
Additional file 4 of The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells
Creators: name: Wu, Yi-Hui
name: Huang, Yu-Fang
name: Wu, Pei-Ying
name: Chang, Tzu-Hao
name: Huang, Soon-Cen
name: Chou, Cheng-Yang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Additional file 4: Table 1. EOC patient characteristics and the studied biomarkers (n = 161).
Supplementary_file_20200715 – Supplemental material for Research Trends of Acupuncture Therapy on Cancer Over the Past Two Decades: A Bibliometric Analysis
Creators: name: Guo, Jing
name: Pei, Lixia
name: Chen, Lu
name: Chen, Hao
name: Gu, Dongmei
name: Xin, Chen
name: Peng, Yongjun
name: Sun, Jianhua
Publisher: name: SAGE Journals
Year: 2020
Subjects: Health and Community Services
Endocrinology
Oncology and Carcinogenesis not elsewhere classified
Aged Health Care

description: Supplemental material, Supplementary_file_20200715 for Research Trends of Acupuncture Therapy on Cancer Over the Past Two Decades: A Bibliometric Analysis by Jing Guo, Lixia Pei, Lu Chen, Hao Chen, Dongmei Gu, Chen Xin, Yongjun Peng and Jianhua Sun in Integrative Cancer Therapies
ANGIOTENSIN-CONVERTING ENZYME AND ITS GENE POLYMORPHISM (I/D) IN ESSENTIAL ARTERIAL HYPERTENSION
Creators: name: Taher, Mohamed A.
name: Boghdady, Ahmed M.
name: Sabet, Eman A.
name: Arafa, Usama A.
name: Abd Elneam, Ahmed I.
Publisher: name: European Chemical Bulletin
Year: 2015

description: The polymorphisms of ACE gene has been investigated using polymerase chain reaction for detection of ACE I/D genotype  frequency in hypertensive cases in sector of Egyptian population. Serum ACE is significant higher in hypertensive group than normotensive one (27.5± 4.4 and 21.3± 5.4 ng/m respectively. Means SBP (systolic blood pressure), DBP (diastolic blood pressure) and urinary protein excretion in DD genotype were 181±17 mmHg, 112±19mmHg, 38±4.8mg/dl and 141.5± 36.8mg/24h respectively but, in II genotype were 142± 10 mmHg, 99± 13 mmHg, 43.5±4 mg/dl and 116.4± 36 mg/24h respectively. In hypertensive patients, serum ACE levels in DD, ID and II genotypes were 36.2± 5.7, 22.1± 3.7 and 24.5± 4.9 respectively. D/D ACE gene polymorphism plays a role in the development of target organ damage in sever essential hypertension and might have a prognostic value. It can be considered as one of risk factor of hypertension.
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
“Over the Ruined Factory There's a Funny Noise”: Throbbing Gristle and the Mediatized Roots of Noise in/as Music
Creators: name: Jan Kromhout, Melle
Publisher: name: Humanities Commons
Year: 2011
Subjects: subject: Popular music
subject: Media studies
subject: Noise
subject: Industrial music

description: Britain's Throbbing Gristle used a kind of aural and conceptual violence to pursue specific ideological goals. The concept of noise is crucial to the understanding of this use, but is often explained in a limiting discourse. Friedrich Kittler offers an alternative approach by showing how the introduction of media technology initially formed this discourse. When one assesses the use of noise and its relation to violence from such a media historic point of view, Throbbing Gristle's layered work becomes conceptually coherent and turns out to be an exemplary case study for the status of noise in popular music more generally.
ADENOSINE DEAMINASE AND ITS ISOENZYMES IN ASCITES WITH DIFFERENT ETIOLOGIES
Creators: name: Abdelmoaty, Mohamed Ahmed
name: Bogdady, Ahmed Mohamed Bogdady
Publisher: name: European Chemical Bulletin
Year: 2016

description: Adenosine deaminase (ADA) activity was increased in certain clinical conditions including tuberculosis and bacterial infections. In this study, the ADA isoenzymes patterns were assayed in ascites of different etiologies Ninety two Patients with ascites were selected and investigated to determine the cause of ascites. Total ADA and its isoenzymes were assayed spectophotometerically besides polyacrylamide gel electrophoretic. Results. In ascitic fluid secondary to parainfection, TB, abdominal cancer and liver cirrhosis, total ADA were 34.5± 11.1, 87.6± 23.6, 32.7± 10.1 and 28.5± 7.3 U/l respectivly, ADA1m were 24.5± 11.1, 4.3± 1.9, 2.8± 2.2 and 10.1± 3.3 U/l respectivly, ADA1c were 7.8± 3, 16.5± 6.2, 4.7± 1.3 and 10.1± 3.3 U/l respectivly but, ADA2 were 2.2± 3.9, 65.9±  33.5, 26.2± 6.2 and 3.3± 9.7 U/l respectivly. Conclusion Total ADA above 41 U/l and ADA2 above 32 U/l in ascetic fluid have high sensitivity value in TB peritonitis. Ascitic fluid ADA1m/ADA more than 50% has high specificty value in parainfective peritonitis. Total ascitic ADA less than 41 U/L and ADA2/ADA ratio more than 50% have high specificity in abdominal cancer.
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
Role of artificial intelligence and machine learning in nanosafety
Creators: name: Winkler, David
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Robotics and automation provide potentially paradigm shifting improvements in the way materials are synthesized and characterized, generating large, complex data sets that are ideal for modeling and analysis by modern machine learning (ML) methods. Nanomaterials have not yet fully captured the benefits of automation, so lag behind in the application of ML methods of data analysis. Here, some key developments in, and roadblocks to the application of ML methods are reviewed to model and predict potentially adverse biological and environmental effects of nanomaterials. This work focuses on the diverse ways a range of ML algorithms are applied to understand and predict nanomaterials properties, provides examples of the application of traditional ML and deep learning methods to nanosafety, and provides context and future perspectives on developments that are likely to occur, or need to occur in the near future that allow artificial intelligence to make a deeper contribution to nanosafety.
Autoimmune thyroiditis in type 1 diabetes mellitus
Creators: name: Abd Alrheam, Ali Ismaeil Ali
name: Al Shehri, Zafer Saad
name: Gomaa, Heba F.
name: Al Mutairi, Nasser Badi K
Publisher: name: European Chemical Bulletin
Year: 2016

description: A variety of thyroid abnormalities may co-exist and interact with diabetes mellitus (DM). Autoimmune thyroid diseases are frequent in patients with type I diabetes mellitus. Aim: In this study we aimed to compare the frequency of thyroid antibodies among diabetic patients with type 1 and type 2 (DM).

Material and methods: Fifty diagnosed type-1 DM patients were classified into two groups each consists of 25 subjects of early adulthood (18 to 35 yrs) and later adulthood (after35 yrs). Twenty-five age matched subjects with later adult hood DM type II are taken as controls. All the subjects had no history of previous thyroid diseases. Informed consent was obtained from all the subjects. The separated serum is used to estimate serum Free T3 and  Free T4 and TSH using automated analyzer (Elecsys 2010 platform, Roche Diagnostics GmbH) according to instruction of the manufacturer. Thyroid peroxidase antibody (TPO-Ab) and  Thyroglobulin antibodies (TG-Ab) were determined according to the manufacturer instruction by the supplier (DRG, Germany).

Results: The serum  levels of FT4 and TSH in early and late adulthood  type 1 DM were  not  statistically  different  than  that  of  later adulthood Type II diabetic  patients.  But the  serum  FT3  levels  were  found to be lower  in  type-1  diabetics  patients as compared  to  type II DM. In addition there was a slightly increase in the values of anti-TPO and anti-TG antibodies in later adult hood of type I   DM when compared to the values of early adult hood of type I DM. And there was significant increase in the values of anti-TPO and anti-TG antibodies in later adulthood of type I DM when compare to the values of later adulthood of type II DM
Conclusion:Estimation  of  thyroid  antibodies  should  be  done  periodically for very diabetic  patients and subjects with  positive  antibodies  should  be  monitored  for  TSH  elevation  at  yearly  intervals  with  the  goal  of  early  detection to  prevent  the  possible  adverse  effects.
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
Supplemental_file_2 – Supplemental material for Autism and Williams syndrome: Dissimilar socio-cognitive profiles with similar patterns of abnormal gene expression in the blood
Creators: name: Niego, Amy
name: Benítez-Burraco, Antonio
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: Education
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, Supplemental_file_2 for Autism and Williams syndrome: Dissimilar socio-cognitive profiles with similar patterns of abnormal gene expression in the blood by Amy Niego and Antonio Benítez-Burraco in Autism
Fabrication, characterization, and docking studies of furosemide-loaded nanosponges using the emulsion solvent diffusion method
Creators: name: Liaqat, Rabia
name: Rasool, Fatima
name: Noreen, Sobia
name: Rai, Nadia
name: Naseem, Ayesha
name: Shoaib, Muhammad Hamza
name: Mahmood, Hassan
name: Ashraf, Muhammad Azeem
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Biophysics
Biochemistry
Space Science
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: This study aimed to fabricate, characterize, and perform molecular docking of furosemide-loaded nanosponges (NSs) using the emulsion solvent diffusion method. Sustained-release NS formulations of furosemide were developed using ethylcellulose, polyvinyl alcohol (PVA), and dichloromethane (DCM) via the emulsion solvent diffusion technique. The formulations were evaluated for production yield, actual drug content, entrapment efficiency, drug-polymer compatibility, surface morphology, docking study, and in vitro drug release. SEM images displayed the nanosized, spherical, porous, and spongy texture of furosemide NS. Fourier-transform infrared spectroscopy (FTIR) spectra showed no drug-polymer incompatibility. Powder X-ray diffraction (PXRD) analysis indicated an amorphous state of furosemide, while differential scanning calorimetry (DSC) suggested drug-polymer complexation. In vitro studies demonstrated sustained drug release for up to 10 h. Molecular docking supported stable interactions between furosemide and polymers. Molecular dynamics (MD) simulations further revealed adequate hydrogen bonding and diffusion behavior, confirming polymer composition-dependent release and structural stability. These findings indicate that furosemide-loaded NSs are a promising sustained-release delivery system capable of reducing dosing frequency and enhancing patient compliance.
Improving the Smithsonian National Museum of Natural History Collections Data Quality
Creators: name: Nguyen, Ducky
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference poster on Improving the Smithsonian National Museum of Natural History Collections Data Quality by Ducky Nguyen of Smithsonian NMNH Washington United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Supplemental Material, CONSORT_a - Effectiveness of Continuous Positive Airway Pressure Versus Mandibular Advancement Device in Severe Obstructive Sleep Apnea Patients With Mandibular Retrognathia: A Prospective Clinical Trial
Creators: name: Lai, Haichun
name: Huang, Wei
name: Chen, Wei
name: Wang, Desheng
Publisher: name: SAGE Journals
Year: 2022
Subjects: Otorhinolaryngology

description: Supplemental Material, CONSORT_a for Effectiveness of Continuous Positive Airway Pressure Versus Mandibular Advancement Device in Severe Obstructive Sleep Apnea Patients With Mandibular Retrognathia: A Prospective Clinical Trial by Haichun Lai, Wei Huang, Wei Chen and Desheng Wang in Ear, Nose & Throat Journal
Supplemental Material, CONSORT_b - Effectiveness of Continuous Positive Airway Pressure Versus Mandibular Advancement Device in Severe Obstructive Sleep Apnea Patients With Mandibular Retrognathia: A Prospective Clinical Trial
Creators: name: Lai, Haichun
name: Huang, Wei
name: Chen, Wei
name: Wang, Desheng
Publisher: name: SAGE Journals
Year: 2020
Subjects: Otorhinolaryngology

description: Supplemental Material, CONSORT_b for Effectiveness of Continuous Positive Airway Pressure Versus Mandibular Advancement Device in Severe Obstructive Sleep Apnea Patients With Mandibular Retrognathia: A Prospective Clinical Trial by Haichun Lai, Wei Huang, Wei Chen and Desheng Wang in Ear, Nose & Throat Journal
From used cooking oils to P3HB  biopolymers, a techno-economic  feasibility study for production  plants in Italy to foster the  creation of a new value chain
Creators: name: Gambuzzi, Elisa
name: Vaněk, Martin
Publisher: name: Zenodo
Year: 2025

description: This study conducted a comprehensive economic feasibility analysis of a biotechnological plant that converts used cooking oils into the poly-3-hydroxybutyrate (P3HB) polymer used as an ingredient by the cosmetics industry, especially as a UV filter.
Supplementary_Material – Supplemental material for Systematic review and meta-analysis of randomized controlled trials assessing the impact of Baduanjin exercise on cognition and memory in patients with mild cognitive impairment
Creators: name: Yu, Liqiang
name: Liu, Fang
name: Nie, Pingying
name: Shen, Cuiling
name: Chen, Junying
name: Yao, Liqun
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Orthopaedics
subject: Sports Medicine

description: Supplemental material, Supplementary_Material for Systematic review and meta-analysis of randomized controlled trials assessing the impact of Baduanjin exercise on cognition and memory in patients with mild cognitive impairment by Liqiang Yu, Fang Liu, Pingying Nie, Cuiling Shen, Junying Chen and Liqun Yao in Clinical Rehabilitation
Online_Appendix – Supplemental material for Institutional Context and Accountability for Political Distrust
Creators: name: Jones, David R.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, Online_Appendix for Institutional Context and Accountability for Political Distrust by David R. Jones in Political Research Quarterly
Lipid Profile and Fatty-Acid Composition of Human Serum in  Hypertension Patients
Creators: name: Jasim, Mohamed A. H.
Publisher: name: European Chemical Bulletin
Year: 2015

description: The aim of this study was designed to determine the effect of hypertension on the level of  lipid fractions and percentage of fatty acids in serum .The study included( 50) patients with hypertension ,blood was taken after( 10-12) hour fasting . The age of patients was between (60-80) year. Blood samples from (50) normal subject with the same age were collected as control .The patients samples collection were from the medical word  . A number of biochemical parameters were measured using enzymatic kits methods also the analysis and  the measurement of  percentage of fatty acids in fatty component of serum (cholesterol ester, phospholipids ,triglyceride) separated by thin layer chromatography(TLC) followed by transmethylation of fatty acids and measurement of  fatty acids percentage  using  Capillary Gas Chromatography (CGC).The result of this study showed that there is a significant differences in the level of studied  biochemical parameter and fatty acids percentage in hypertension patients compared with the control group. The results of this study also showed that a significant increase in level of (TG) in serum of hypertension patients  . The result showed that a significant increase in percentage of (PUFA) in (PL) part
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
Exosomes and soluble secretome from hormone-treated endometrial epithelial cells direct embryo implantation
Creators: name: S Gurung
name: Greening, David
name: S Catt
name: L Salamonsen
name: J Evans
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © The Author(s) 2020. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. All rights reserved. A successful pregnancy requires a synchronous dialogue between endometrium and embryo within the endometrial milieu. The aim of this study was to assess the role in the implantation of mediators in the endometrial milieu. Total secretome (TS), soluble secretome (SS) and small extracellular vesicles (containing exosomes) were generated from hormonally primed human endometrial epithelial cell culture medium. Human trophectoderm stem cell-derived spheroids were cultured with TS, SS or exosomes (30 mg/ml) on hormonally primed epithelial cells, with exosomes significantly increasing cell adhesion and outgrowth. Furthermore, F1 mouse 2-cell embryos were cultured in groups for 48 h followed by culture with each secretome fraction (30 mg/ml) for 48 h. Blastocyst cell number and hatching were quantified. In addition, blastocysts were further cultured on a fibronectin matrix for 72 h or transferred to recipient mice (with corresponding secretomes) with embryo implantation assessed after 6 days. Exosomes significantly increased total cell number in mouse embryos and complete hatching from zona pellucida, with both exosomes and SS significantly enhancing mouse embryo outgrowth. Importantly, exosomes increased the embryo implantation rate in comparison to other secretome fractions (normalized based on treatment amount) from the endometrial epithelia. These data indicate that endometrial epithelial exosomes support embryo growth, development and implantation while the SS has selective involvement specifically on mouse embryo outgrowth. This finding provides new insights into the molecular differences of endometrial secretome components in implantation and early embryo development and may implicate endometrial exosomes in the pathophysiology of implantation failure in infertility.
Comparative Study of Chemical Composition of Calotropis gigantea Flower, Leaf and Fruit Essential Oil
Creators: name: Singh, Minakshi
name: Javed, Kalim
Publisher: name: European Chemical Bulletin
Year: 2015

description: Essential oil from flowers, leaves and fruits of Calotropis gigantea (L), was extracted by hydro distillation method. Total 21 components in leaves, 43 components in flowers and 21 components in fruits were identified. The extracted oil was characterized by GC and GC-MS techniques. Constituents common to flower, leaves and fruit were 3-Hexen-1-ol, Benzaldehyde, Benzyl alcohol, ± Linalool, Oct-3-en-2-ol, Phenethyl alcohol, α- Terpineol, 2,4-dimethyl-Acetophenone, 4-vinyl Guaiacol  and n-Tetradecane.
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
Novel e-Health Applications for the Management of Cardiometabolic Risk Factors in Children and Adolescents in Greece
Creators: name: A Tragomalou
name: Moschonis, George
name: Y Manios
name: P Kassari
name: I Ioakimidis
name: C Diou
name: L Stefanopoulos
name: E Lekka
name: N Maglaveras
name: A Delopoulos
name: E Charmandari
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Obesity in childhood and adolescence represents a major health problem. Novel e-Health technologies have been developed in order to provide a comprehensive and personalized plan of action for the prevention and management of overweight and obesity in childhood and adolescence. We used information and communication technologies to develop a “National Registry for the Prevention and Management of Overweight and Obesity” in order to register online children and adolescents nationwide, and to guide pediatricians and general practitioners regarding the management of overweight or obese subjects. Furthermore, intelligent multi-level information systems and specialized artificial intelligence algorithms are being developed with a view to offering precision and personalized medical management to obese or overweight subjects. Moreover, the Big Data against Childhood Obesity platform records behavioral data objectively by using inertial sensors and Global Positioning System (GPS) and combines them with data of the environment, in order to assess the full contextual framework that is associated with increased body mass index (BMI). Finally, a computerized decision-support tool was developed to assist pediatric health care professionals in delivering personalized nutrition and lifestyle optimization advice to overweight or obese children and their families. These e-Health applications are expected to play an important role in the management of overweight and obesity in childhood and adolescence.
In with the Old, In with the New: Interdigitating Museum Collections and Equipment
Creators: name: Jones, Lynn
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference oral presentation on In with the Old, In with the New: Interdigitating Museum Collections and Equipment by Museum Assistant Lynn Jones of Museum Assistant Yale Peabody Museum of Natural History New Haven United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Additional file 1 of The relationship between preserved ratio impaired spirometry and mortality in the myocardial infarction survivors: a population-based cohort study
Creators: name: Li, Dan
name: Ruan, Zhishen
name: Xie, Shen
name: Xuan, Shunchao
name: Zhao, Hengyi
name: Wu, Bo
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary file: Sensitivity analysis
Determination of the Total Phenolic content, Total Flavonoid Content, Antioxidant Activity and Some Bioactive compounds of the Lebanese Eryngium creticum L.
Creators: name: Zeidan, Saeed
name: Hijazi, Akram
name: Rammal, Hassan
name: Al Bazzal, Ali
name: Annan, Hussein
name: Al-Rekaby, Abd Al-Ameer N.
Publisher: name: European Chemical Bulletin
Year: 2015

description: Polyphenolic compounds are bioactive substances widely distributed in the plant kingdom. They act as natural antioxidants and their presence contributes to the color, flavor, and aroma of food. Therefore, they are considered dietary antioxidants with interesting benefits to health. In this article the extraction of total phenolics, total Flavonoids and antioxidants activity from Eryngium creticum was determined after obtaining the plant extracts by conventional and non-conventional extraction techniques. Also this study aims to determine the bioactive constituents present in E. creticum extracts by using GC-MS method. The results obtained show that microwave assisted extraction is the best technique used for the extraction of phenolic compounds and flavonoids from E. creticum giving a yield of 34.46 µg/mL and 21.05 µg/mL respectively. However, the antioxidants activity, evaluated by the DPPH assay was low in all the extraction techniques. Also the results showed the presence of 9 fatty acid derivatives, most of them have therapeutic effects on human health. These results explain the use of E. creticum in traditional medicine to treat various diseases.
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
Additional file 1 of Vaccine coverage and effectiveness against laboratory-confirmed symptomatic and severe Covid-19 in indigenous people in Brazil: a cohort study
Creators: name: Pescarini, Julia M.
name: Cardoso, Andrey M.
name: Santos, Ricardo Ventura
name: Scaff, Priscila F.
name: Paixao, Enny S.
name: Ranzani, Otavio T.
name: Cerqueira-Silva, Thiago
name: Boaventura, Viviane S.
name: Bertoldo-Junior, Juracy
name: de Oliveira, Vinicius A.
name: Werneck, Guilherme L.
name: Barreto, Mauricio L.
name: Barral-Netto, Manoel
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Supplementary Material 1
EXTRACTION OF THORIUM (IV) WITH SODIUM BENTONITE AND MAGHEMIT CONTAINING MAGNETIC NANOCOMPOSITE BENTONITES
Creators: name: Miraoui, Abdelkader
name: Didi, Mohamed Amine
Publisher: name: European Chemical Bulletin
Year: 2015

description: Liquid-solid extraction of Thorium (IV) is made by sodium bentonite and Magnetic bentonite.  Magnetic  adsorbent  can  be  quickly  separated  from  a  medium  by  a simple  magnetic  process, in  view  of  these properties, some parameters were studied to assess the performance of maghemite nanocomposite clay for the removal of Thorium ions. The operating variables studied are initial Th (IV) concentration, pH, ionic strength, temperature and contact time. The time needed for magnetic bentonite to adsorb the maximum of Th (IV) is 45 minutes and 60 minutes for sodium bentonite. For magnetic bentonite, optimal extraction yield was achieved in a initial pH equal at 6.2 and for sodium bentonite, the variation of initial pH has no influence on the extraction yield. The sorption capacities of sodium bentonite and magnetic bentonite are 41.24 and 31.34 mg.g-1 respectively. Adsorption equilibrium data were calculated for Langmuir and Freundlich isotherms. It was found that the sorption of Th (IV) on sodium and magnetic bentonite was better suited to the Langmuir adsorption model. Thermodynamics data leads to endothermic and spontaneous process for magnetic bentonite and exothermal for sodium bentonite. The quantitative elution study of Thorium can be realized with acetic acid for sodium bentonite and sulfuric acid for magnetic bentonite.
description: European Chemical Bulletin, Vol 4, No 10-12 (2015): European Chemical Bulletin
CloutContracts, Game Theory, and the Social Physics of Humans
Creators: name: Magdy Kamal, Andrew
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Blockchains (Databases)
subject: Blockchains (Databases)--Law and legislation
subject: Political science
subject: FOS: Political science
subject: Anarchism
subject: Cryptocurrencies
subject: Capitalism
subject: Social sciences
subject: FOS: Social sciences
subject: Physics--Social aspects

description: Decision making all seems like forms of randomization, but some of them may follow distinctive cognitive patterns. We all have distinct forms of communication with each other, but all utilize some sort of consciousness, and our thought processes all seem to have both internal and external physiological attributes. We have similar guilt variances in relation to behavioral patterns, we have different ways we react to certainty vs. uncertainty, and we have similar as well as distinct instincts. How people react to social influence and perceived value as well as emotionally driven responses are also especially interesting. The concept of CloutContracts, for conversation purposes, is a blockchain platform that has originally been designed to democratize social media. It has also been meant to be a rollup layer amongst other things. However, a core premise is how do people react to perceived value if the decision making is decentralized as opposed to centralized? What is human influence? Then again, are humans and the way we think somehow universally mathematically representable?