cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Two Geminin homologs regulate DNA replication in silkworm, Bombyx mori
Creators: name: Tang, Xiao-Fang
name: Chen, Xiang-Yun
name: Zhang, Chun-Dong
name: Li, Yao-Feng
name: Liu, Tai-Hang
name: Zhou, Xiao-Lin
name: Wang, La
name: Zhang, Qian
name: Chen, Peng
name: Lu, Cheng
name: Pan, Min-Hui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: DNA replication is rigorously controlled in cells to ensure that the genome duplicates exactly once per cell cycle. Geminin is a small nucleoprotein, which prevents DNA rereplication by directly binding to and inhibiting the DNA replication licensing factor, Cdt1. In this study, we have identified 2 Geminin genes, BmGeminin1 and BmGeminn2, in silkworm, Bombyx mori. These genes contain the Geminin conserved coiled-coil domain and are periodically localized in the nucleus during the S-G2 phase but are degraded at anaphase in mitosis. Both BmGeminin1 and BmGeminin2 are able to homodimerize and interact with BmCdt1 in cells. In addition, BmGeminin1 and BmGeminin2 can interact with each other. Overexpression of BmGeminin1 affects cell cycle progression: cell cycle is arrested in S phase, and RNA interference of BmGeminin1 leads to rereplication. In contrast, overexpression or knockdown of BmGeminin2 with RNAi did not significantly affect cell cycle, while more rereplication occurred when BmGeminin1 and BmGeminin2 together were knocked down in cells than when only BmGeminin1 was knocked down. These data suggest that both BmGeminin1 and BmGeminin2 are involved in the regulation of DNA replication. These findings provide insight into the function of Geminin and contribute to our understanding of the regulation mechanism of cell cycle in silkworm.
Knockdown of BC200 RNA expression reduces cell migration and invasion by destabilizing mRNA for calcium-binding protein S100A11
Creators: name: Heegwon Shin
name: Jungmin Lee
name: Youngmi Kim
name: Seonghui Jang
name: Yunhee Lee
name: Semi Kim
name: Younghoon Lee
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Although BC200 RNA is best known as a neuron-specific non-coding RNA, it is overexpressed in various cancer cells. BC200 RNA was recently shown to contribute to metastasis in several cancer cell lines, but the underlying mechanism was not understood in detail. To examine this mechanism, we knocked down BC200 RNA in cancer cells, which overexpress the RNA, and examined cell motility, profiling of ribosome footprints, and the correlation between cell motility changes and genes exhibiting altered ribosome profiles. We found that BC200 RNA knockdown reduced cell migration and invasion, suggesting that BC200 RNA promotes cell motility. Our ribosome profiling analysis identified 29 genes whose ribosomal occupations were altered more than 2-fold by BC200 RNA knockdown. Many (> 30%) of them were directly or indirectly related to cancer progression. Among them, we focused on S100A11 (which showed a reduced ribosome footprint) because its expression was previously shown to increase cellular motility. S100A11 was decreased at both the mRNA and protein levels following knockdown of BC200 RNA. An actinomycin-chase experiment showed that BC200 RNA knockdown significantly decreased the stability of the S100A11 mRNA without changing its transcription rate, suggesting that the down-regulation of S100A11 was mainly caused by destabilization of its mRNA. Finally, we showed that the BC200 RNA-knockdown-induced decrease in cell motility was mainly mediated by S100A11. Together, our results show that BC200 RNA promotes cell motility by stabilizing S100A11 transcripts.
Two new cadinane-type sesquiterpenes from cultures of the basidiomycete Trichaptum pargamenum
Creators: name: Tang, Bin
name: Du, Xi
name: Long, Han-An
name: Du, Jun
name: Guo, Jian-Min
name: Hu, Xin
name: Tu, Hua
name: Yang, Li
name: Liu, Hong-Jin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Two new cadinane-type sesquiterpenes, trichapargins A (1) and B (2), were isolated from cultures of the basidiomycete Trichaptum pargamenum. Their structures were elucidated on the basis of extensive spectroscopic methods. Trichapargin A showed weak activity to SW480 with an IC50 value of 24.8 μM.
Field-angle dependence of thermal Hall conductivity in magnetically ordered Kitaev-Heisenberg system
Creators: name: Koyama, Shinnosuke
name: Nasu, Joji
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study magnetic excitations and thermal Hall effect on the Kitaev-Heisenberg model under magnetic fields. By employing the spin-wave theory for the magnetic orders realized in this model, we examine the topological nature of the spin-wave dispersions and calculate the thermal Hall conductivity. The comprehensive investigations on the field-angle dependence clarify that the thermal Hall conductivity is sensitive to the spin ordered pattern and excitation spectra of magnons; this quantity is enhanced by the noncoplanar spin configurations and small magnon gap in the excitation spectrum. On the other hand, we also find a common feature in the field-angle dependence of the thermal Hall conductivity. It vanishes when the magnetic field is on the planes spanned by the spin axes. We reveal that the behavior is intrinsic to the Kitaev -Heisenberg model in an applied field and demonstrate that the introduction of the off-diagonal spin interaction causes the disappearance of the feature in the thermal Hall conductivity.
description: 12 pages, 10 figures
Development of Detailed Surface Reaction Mechanism of C2H4/C3H6 Oxidation on Pt/Al2O3 Monolith Catalyst Based on Gas Phase and Surface Species Analyses
Creators: name: Naing, Set
name: Kristyawan, I Putu Angga
name: Murakami, Hiroshi
name: Hinokuma, Satoshi
name: Matsumoto, Yuhei
name: Omori, Tomohito
name: Wang, Yanlei
name: Yokohata, Hideaki
name: Kawano, Michiharu
name: Takebayashi, Hiroyuki
name: Miyoshi, Akira
name: Shimokuri, Daisuke
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: In this study, reaction characteristics of C2H4/O2 and C3H6/O2 on practical Pt/Al2O3 monolith catalyst are investigated, and a simplified microkinetic surface reaction mechanism is proposed by taking the observed surface species and their occupied active surface sites into account. Importance of more than one active PGM surface site occupations at the adsorption step of C2H4 or C3H6 and multiple-sited stable intermediate CHx species are considered. Gas phase experimental results show that the light-off temperature as well as complete conversion temperature of both C2H4/O2 and C3H6/O2 mixture shift to lower side with the increase in oxygen concentration. The surface species analyses show the presence of stable intermediate CHx species and linearly adsorbed CO on the platinum surface. Numerically simulated light-off performance with the proposed reaction mechanism shows good agreement with the experimental results of C2H4/O2 and C3H6/O2. Moreover, simulation results also agree well with the additional experimental results with multiple gas compositions and validate the proposed detailed reaction mechanism.
HSK-1. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: HSK-1 drillhole record
title: Umfrage zum Bedarf einer e-Learning-Plattform für Ärzte in der HNO-Facharzt-Weiterbildung
Creators: name: Shabli, Sami
name: Heuermann, Katharina
name: Leffers, David
name: Kriesche, Franziska
name: Abrams, Nils
name: Yilmaz, Murat
name: Klußmann, Jens Peter
name: Guntinas-Lichius, Orlando
name: Beule, Achim
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: Online-Umfrage
subject: e-Learning-Plattform
subject: HNO-Weiterbildung
subject: e-learning
subject: Assistenzarztausbildung
subject: 610 Medical sciences; Medicine

description: Hintergrund: Interaktive e-learning-Plattformen werden in Zukunft das klassische Lehrbuch ersetzen und das Lernen verändern. Diese Plattformen können neben Texten und Abbildungen auch Videosequenzen und Audioaufnahmen umfassen. Ein solches Medium speziell für die HNO Heilkunde existiert[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte
Breaking the sporoderm of Ganoderma lucidum spores by combining chemical reaction with physical actuation
Creators: name: Wang, Jiajia
name: Ke, Rui
name: Zhang, Shengyi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Information Systems not elsewhere classified

description: The hard and indissolvable sporoderm of Ganoderma lucidum spore (GLS) hinders the release of bioactive components that are significant to disease treatment and vitality enhancement. In this paper, a strategy to break sporoderm was proposed, in which the chemical reaction was cooperated with physical actuation (ultrasonication and refrigeration). Dealing with this chemicophysical treatment, the porous sporoderm of GLS was formed, which was confirmed by scanning electron microscope (SEM). The effect factors and mechanism of breaking sporoderm were discussed, and the efficiency of breaking sporoderm was evaluated by detecting the dissolution behaviour of inner triterpenoids in GLS. In addition, aiming to improve the solubility and stability of GLS product, the β-cyclodextrin was used to seal the holes on sporoderm of GLS product. The results show that the developed method is effective and feasible in producing high-bioactive and stable GLS product.
Effects of Globally Stratified Temperature Distributions and NTC Characteristics on End-gas Combustion Modes
Creators: name: Nogawa, Takahisa
name: Terashima, Hiroshi
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: This study numerically investigates the effects of stratified temperature distributions on the end-gas combustion mode in a constant volume reactor. The initial temperature in the reactor was globally stratified with linear gradients. The effects of negative temperature coefficient (NTC) characteristics are addressed through a comparison between the results of a non-NTC fuel and an NTC fuel. The compressible Navier–Stokes equations are solved with detailed chemistry. The results show that the addition of large temperature gradients such as −10 or −5 K/cm can prevent the pressure wave development associated with end-gas autoignition, and the knocking intensity is significantly reduced. In contrast, small temperature gradients such as −1 K/cm lead to the generation of the developing detonation mode and thus to large knocking intensities. In the NTC fuel case, the knocking intensity becomes relatively large because the spatial gradient of the ignition delay time decreases even with the addition of large temperature gradients, especially in the NTC regime. Based on all the results, a correlation is presented between the initial temperature and the reaction front speed (the spatial gradient of the ignition delay time) for the prediction of end-gas combustion mode. The correlation suggests that the possibility of preventing large knocking intensities by temperature gradients is reduced under high-pressure conditions because of the increase in the reaction front speed. Consequently, this study suggests that very large temperature gradients would be required under high-pressure conditions to prevent large knocking intensities under the concept of thermal stratification.
Poly(glycerol methacrylate)-based degradable nanoparticles for delivery of small interfering RNA
Creators: name: Morsi, Noha G.
name: Ali, Shimaa M.
name: Elsonbaty, Sherouk S.
name: Afifi, Ahmed A.
name: Hamad, Mostafa A.
name: Gao, Hui
name: Elsabahy, Mahmoud
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Space Science
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Nucleic acids therapeutic efficiency is generally limited by their low stability and intracellular bioavailability, and by the toxicity of the carriers used to deliver them to the target sites. Aminated poly(glycerol methacrylate) polymers are biodegradable and pH-sensitive polymers that have been used previously to deliver antisense oligonucleotide and show high transfection efficiency. The purpose of this study is to compare the efficiency and toxicity of aminated linear poly(glycerol methacrylate) (ALT) biodegradable polymer to the most commonly used cationic degradable (i.e. chitosan) and non-degradable (i.e. polyethylenimine (PEI)) polymers for delivery of short interfering RNA (siRNA). ALT, PEI and chitosan polymers were able to form nanosized particles with siRNA. Size, size-distribution and zeta-potential were measured over a wide range of nitrogen-to-phosphate (N/P) ratios, and the stability of the formed nanoparticles in saline and upon freeze-drying was also assessed. No significant cytotoxicity at the range of the tested concentrations of ALT and chitosan nanoparticles was observed, whereas the non-degradable PEI showed significant toxicity in huh-7 hepatocyte-derived carcinoma cell line. The safety profiles of the degradable polymers (ALT and chitosan) over non-degradable PEI were demonstrated in vitro and in vivo. In addition, ALT nanoparticles were able to deliver siRNA in vivo with significantly higher efficiency than chitosan nanoparticles. The results in the present study give evidence of the great implications of ALT nanoparticles in biomedical applications due to their biocompatibility, low cytotoxicity, high stability and simple preparation method.
title: KLIMONAS-Ch28-A02 - Prédiction par apprentissage automatique (K-NN) des proximités de la première molaire inférieure de la souris de Klimonas avec les souris de référence prises en compte dans la figure 28-5
title: KLIMONAS-Ch28-A02 - Machine learning prediction (K-NN) of the proximities of the mouse first lower molar of Klimonas with the mice references taken into account in figure 28-5
Creators: name: CUCCHI, Thomas
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: Annexe de : Vigne J.-D., Briois F., Guilaine J. (dir.), « Klimonas, un village néolithique pré-céramique ancien à Chypre », Gallia Préhistoire & Paléorient, Supplément international 1, CNRS Éditions, Paris, 2023.
description: Appendix of: Vigne J.-D., Briois F., Guilaine J. (eds.), « Klimonas, an Early Pre-Pottery Neolithic village in Cyprus », Gallia Préhistoire & Paléorient, International Supplement 1, CNRS Éditions, Paris, 2023.
การประเมินค่าสี รงควัตถุ และกิจกรรมสารต้านอนุมูลอิสระจากดอกไม้รับประทานได้กลุ่มสีแดงชมพูของไทยและการประยุกต์ใช้ในซอร์เบท์น้ำมะพร้าว
Creators: name: ศุภธิดา พิมพิสณฑ์, ปาริสุทธิ์ เฉลิมชัยวัฒน์, ทัศนีย์ ลิ้มสุวรรณ
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: ดอกไม้รับประทานได้
ผงสีธรรมชาติ
รงควัตถุ
กิจกรรมสารต้านอนุมูลอิสระ
ซอร์เบท์

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 3, 429-442
Mamiyev, Balayeva - 2015 - Synthesis and characterization of CdS nanocrystals and maleic anhydride octene-1 copolymer nanocomposite m(2).pdf
Creators: name: Mamiyev, Zamin
Publisher: name: figshare
Year: 2017
Subjects: subject: 20604 Quantum Optics
subject: FOS: Physical sciences
subject: 100708 Nanomaterials
subject: FOS: Nanotechnology
subject: 100707 Nanomanufacturing
subject: 30302 Nanochemistry and Supramolecular Chemistry
subject: FOS: Chemical sciences
subject: 100712 Nanoscale Characterisation

description: nanoparticles
DH-043. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: DH-043 drillhole record
TH1. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: TH1 drillhole record
SPBH-8. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: SPBH-8 drillhole record
1983D. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: 1983D drillhole record
ผลของถ่านชีวภาพร่วมกับการจัดการปุ๋ยต่อผลผลิตและความเข้มข้นธาตุอาหารในถั่วฝักยาวไร้ค้าง
Creators: name: สายชล สุขญาณกิจ, สิริวรรณ สมิทธิอาภรณ์, ธนภัทร ปลื้มพวก, ธนวรรณ พาณิชพัฒน์
Publisher: name: กองบริหารการวิจัย
Year: 2563
Subjects: ถ่านชีวภาพ
ปุ๋ยอินทรีย์
ปุ๋ยเคมี
ถั่วฝักยาวไร้ค้าง

description: วารสารวิทยาศาสตร์และเทคโนโลยี, 28, 3, 443-454
title: A confidence ellipse for the Net Reclassification Improvement
Creators: name: Mühlenbruch, Kristin
name: Kuxhaus, Olga
name: Pencina, Michael J.
name: Boeing, Heiner
name: Liero, Hannelore
name: Schulze, Matthias B.
Publisher: name: Universität Potsdam
Year: 2020

description: The Net Reclassification Improvement (NRI) has become a popular metric for evaluating improvement in disease prediction models through the past years. The concept is relatively straightforward but usage and interpretation has been different across studies. While no thresholds exist for evaluating the degree of improvement, many studies have relied solely on the significance of the NRI estimate. However, recent studies recommend that statistical testing with the NRI should be avoided. We propose using confidence ellipses around the estimated values of event and non-event NRIs which might provide the best measure of variability around the point estimates. Our developments are illustrated using practical examples from EPIC-Potsdam study.
BGS-15. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: BGS-15 drillhole record
title: Multi-Modal Long-Term Person Re-Identification Using Physical Soft Bio-Metrics and Body Figure
Creators: name: Shoukry, Nadeen
name: Abd El Ghany, Mohamed A.
name: Salem, Mohammed A.-M.
Publisher: name: MDPI
Year: 2022

description: Person re-identification is the task of recognizing a subject across different non-overlapping cameras across different views and times. Most state-of-the-art datasets and proposed solutions tend to address the problem of short-term re-identification. Those models can re-identify a person as long as they are wearing the same clothes. The work presented in this paper addresses the task of long-term re-identification. Therefore, the proposed model is trained on a dataset that incorporates clothes variation. This paper proposes a multi-modal person re-identification model. The first modality includes soft bio-metrics: hair, face, neck, shoulders, and part of the chest. The second modality is the remaining body figure that mainly focuses on clothes. The proposed model is composed of two separate neural networks, one for each modality. For the first modality, a two-stream Siamese network with pre-trained FaceNet as a feature extractor for the first modality is utilized. Part-based Convolutional Baseline classifier with a feature extractor network OSNet for the second modality. Experiments confirm that the proposed model can outperform several state-of-the-art models achieving 81.4 % accuracy on Rank-1, 82.3% accuracy on Rank-5, 83.1% accuracy on Rank-10, and 83.7% accuracy on Rank-20.
Conceptualising Differentiated Integration: Governance, Effectiveness and Legitimacy
Creators: name: Lavenex, Sandra
name: Križić, Ivo
Publisher: name: Zenodo
Year: 2019
Subjects: Differentiated integration
European Union
Governance
Legitimacy

description: In light of rising internal cleavages and centrifugal tendencies, differentiated integration (DI) has (re)arisen as a major topic in debates on the future of the European Union. As new forms of participation below the threshold of full membership are needed, this paper provides a conceptualisation of effective and legitimate DI. Going beyond existing scholarship’s focus on the legal dimension of DI, the paper emphasises its organisational component, meaning the variegated participation of EU member states, sub-state entities and third-country actors in the panoply of EU policy-making institutions, such as regulatory agencies and transgovernmental networks. The paper subsequently discusses how to measure effectiveness of such differentiated arrangements in terms of their output, outcome and impact, before theorising under what conditions we are likely to see effective DI. Finally, the paper turns to the question of legitimacy of DI, discussing its meaning, measurement and determinants.
Implementation of New Security Features in CMSWEB Kubernetes Cluster at CERN
Creators: name: Ali, Aamir
name: Imran, Muhammad
name: Kuznetsov, Valentin
name: Trigazis, Spyridon
name: Pervaiz, Aroosha
name: Pfeiffer, Andreas
name: Mascheroni, Marco
Publisher: name: arXiv
Year: 2024
Subjects: subject: Cryptography and Security (cs.CR)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: The CMSWEB cluster is pivotal to the activities of the Compact Muon Solenoid (CMS) experiment, as it hosts critical services required for the operational needs of the CMS experiment. The security of these services and the corresponding data is crucial to CMS. Any malicious attack can compromise the availability of our services. Therefore, it is important to construct a robust security infrastructure. In this work, we discuss new security features introduced to the CMSWEB Kubernetes ("k8s") cluster. The new features include the implementation of network policies, deployment of Open Policy Agent (OPA), enforcement of OPA policies, and the integration of Vault. The network policies act as an inside-the-cluster firewall to limit the network communication between the pods to the minimum necessary, and its dynamic nature allows us to work with microservices. The OPA validates the objects against some custom-defined policies during create, update, and delete operations to further enhance security. Without recompiling or changing the configuration of the Kubernetes API server, it can apply customized policies on Kubernetes objects and their audit functionality enabling us to detect pre-existing conflicts and issues. Although Kubernetes incorporates the concepts of secrets, they are only base64 encoded and are not dynamically configured. This is where Vault comes into play: Vault dynamically secures, stores, and tightly controls access to sensitive data. This way, the secret information is encrypted, secured, and centralized, making it more scalable and easier to manage. Thus, the implementation of these three security features corroborate the enhanced security and reliability of the CMSWEB Kubernetes infrastructure.
description: 26TH INTERNATIONAL CONFERENCE ON COMPUTING IN HIGH ENERGY & NUCLEAR PHYSICS - 2023
title: Persistente Identifikatoren
Creators: name: Gstrein, Silvia
name: Kaier, Christian
Publisher: name: Universität Innsbruck
Year: 2020

description: Im HRSM-Projekt e-Infrastructures Austria Plus widmete sich das Arbeitspaket "Persistente Identifikatoren" der Förderung der Zitierbarkeit von Forschenden und Forschungsdaten.
A new cinnamic acid derivative from plant-derived endophytic fungus Pyronema sp.
Creators: name: Deng, Zhangshuang
name: Li, Chengfeng
name: Luo, Dan
name: Teng, Peng
name: Guo, Zhiyong
name: Tu, Xuan
name: Zou, Kun
name: Gong, Dachun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Virology

description: Ten secondary metabolites (1–10) including a new 4-hydroxycinnamic acid derivatives, methyl 2-{(E)-2-[4-(formyloxy)phenyl]ethenyl}-4-methyl-3-oxopentanoate (1), and nine known compounds (2–10) were isolated from an EtOAc extract derived from a solid rice medium of endophytic fungal strain Pyronema sp. (A2-1 & D1-2). Their structures were elucidated from NMR and HRMS data. All the compounds were tested for antibacterial activity against Mycobacterium marinum ATCCBAA-535. Compounds 1, 8 and 9 exhibited moderate antibiotic activity with IC50 of 64, 43 and 32 μM, respectively.
BGS-20. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: BGS-20 drillhole record
MAJOR DELAY FACTORS AND THEIR IMPACT ON THE SUCCESSFUL PROJECT COMPLETION: THE CASE OF OROMIA HEALTH BUREAU HOSPITALS
Creators: name: ABAY KABETO
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2020
Subjects: Major/key factors of delay Impacts of delay Oromia Health Bureau, Hospitals Construction projects

description: Ethiopia’s Construction Sector were faced challenges of delay, which is one of the most common
 problems of construction projects performance. In order to minimize delays, one should only
 have been recognized their causes through serious investigations and need to take correction
 actions timely for successful performance of the projects. Delay of Projects can be due to a
 number of causing reasons which included to groups of the client, the contractor, the consultant,
 or external factors. As per desk review study conducted on Oromia Regional Health Bureau
 (ORHB) hospital project’s, the magnitude of delay was up to 396% of the contract time, which
 indicated that delay was a serious challenge to the performance of the bureau’s projects.
 The aim of the research was to identify key delay causing factors and their impacts as the case of
 ORHB hospitals construction projects and forwarded possible conclusions and recommendations
 based on the findings of the results. After an intensive literature and desk reviews mostly related
 to the field of factors and impacts of delay; a questionnaire survey was conducted to find the
 perception of major parties participating in the performance of the construction projects in the
 region. Accordingly, 60 major causes of delay which categorized into four groups and 20 impacts
 of delay were identified. The survey was carried out through a questionnaire from 42
 participants and collected and analyzed using Relative Importance Index (RII) for ranking. From
 the findings the 4 identified top key factors of delay out of 12 in ORHB were: Cash flow problems
 faced by the contractor, Contractor’s misuse of advance payment, Shortage or delay delivery of
 construction materials and equipment to the construction site by contractor and Instability
 (Security) problems of the region. The finding indicated that contractors were the major source of
 causes of delay. The paper further revealed that the most frequent occurring top 4 delay impacts
 were found Time and Cost overrun, Loss of revenue or profit, Cashflow problems and Escalation
TALABALARNI KONSTRUKTIV KOMPETENSIYALARINI RIVOJLANTIRISHDA TA'LIM TEXNOLOGIYALARINI O'RNI
Creators: name: Isakov, Jasurbek
Publisher: name: Zenodo
Year: 2024

description: Bо‘lajak muhandislarni kоnstruktiv faоliyatiga jalb qilishning mustahkamlash bоsqichi ixtisoslik fanlarni о‘rganish jarayоnida amalga оshiriladi va umumkasbiy tayyоrgarlik fanlari bilan fanlararо о‘zarо alоqadоrlik оrqali bоyitiladi. Mustahkamlash bоsqichini amalga оshirish jarayоnida kоnstruktiv faоliyatining kоgnitiv kоmроnenti axbоrоt texnоlоgiyalarini о‘rganish va kоnstruktiv faоliyatiga jоriy etish оrqali bоyitiladi, kоnstruktiv faоliyatini tashkil etish kо‘nikmalarini shakllantirish оrqali faоliyat kоmроnenti yaxshilanadi va konstruktiv kompetensiyalarining refleksiv kоmроnenti shakllanadi. Bо‘lajak muhandislarni kоnstruktiv faоliyatiga jalb qilishning  mustahkamlash bоsqichining natijasi kasbiy sоhada yanada о‘z о‘zini rivоjlantirish yо‘nalishlaridir.
Two new stilbene trimers from Cynodon dactylon
Creators: name: Li, Bi-Jun
name: Liu, Yao
name: Gu, Ai-Tong
name: Zhang, Qing
name: Chen, Lei
name: Wang, Shu-Mei
name: Wang, Feng
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Virology

description: Many naturally occurring oligostilbenes have drawn considerable attention because of their intricate structures and diverse bioactivities. Two new stilbene trimers, cystibenetrimerol A (1) and cystibenetrimerol B (2) were isolated from the dried grass of Cynodon dactylon (L.) Pers. The planar structures and stereo configurations of them were elucidated by spectroscopic and spectrometric methods. The isolation and structures elucidation of two new stilbene trimers suggested the ordinary grass belonging to the family Poaceae may be a rich source of stilbene oligomers.
Effect of Si/Al ratio on tetralin adsorption on Y zeolite: a DFT study
Creators: name: Wang, Yajun
name: Yang, Chaohe
name: Liu, Yibin
name: Feng, Xiang
name: Fu, Hui
name: Shan, Honghong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology

description: Probing the adsorption of tetralin on zeolite is of prime scientific and industrial importance with the aim to upgrade the industrial process of tetralin cracking. In this work, the effect of Si/Al ratio ranging from 12 to 39 on tetralin adsorption property on Y zeolite is studied by DFT calculations. Tetralin adsorption on Y zeolite corresponds to a π-stacking adsorption mechanism between double bonds of aromatic ring and Brønsted acid sites. Therefore, the number of Brønsted acid sites influences the adsorption properties. Lower Si/Al ratio with more Brønsted acid sites interacting with the aromatic ring of tetralin leads to a higher adsorption energy. Furthermore, the charge and frontier molecular orbital analysis are also performed to understand the influence of Si/Al ratio on adsorption performance. Y zeolite with lower Si/Al ratio shows larger charge difference values and lower HOMO–LUMO gap, which directly manifests the stronger adsorption ability of tetralin and indicates bigger possibility of reacting.
Human microvascular endothelial cell promotes the development of dorsal root ganglion neurons via BDNF pathway in a co-culture system
Creators: name: Yuan, Quan
name: Sun, Li
name: Yu, Honghao
name: An, Chunhou
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Our previous study found that co-culture with human vascular endothelial cells (HMVECs) is beneficial for dorsal root ganglion cells (DRGCs). The goal of the present study is to investigate whether co-culture with HMVECs could promote the development of DRGCs, and whether this effect is induced by the secretion of BDNF by HMVECs. DRGCs were mono-cultured, co-cultured with HMVECs or co-cultured with HMVECs that pre-transfected with BDNF siRNA, the expression of neurite formation and branching factors were determined. The results showed that transfecting with BDNF siRNA inhibited BDNF expression and reduced BDNF secretion. Co-culture with HMVECs increased the expression of Etv4, Etv5, FN-L, FN-M, and GAP-43 in DRGCs that accompanied by the activation of ERK pathway. However, these changes were all reversed by the inhibition of BDNF in HMVECs. In conclusion, our data demonstrate that HMVECs potentiated DRGCs development at least partly by the secretion of BDNF in the co-culture system.
Mechanically controlling the reversible phase transformation from zinc blende to wurtzite in AlN
Creators: name: Li, Zhen
name: Yadav, Satyesh
name: Chen, Youxing
name: Li, Nan
name: Liu, Xiang-Yang
name: Wang, Jian
name: Zhang, Shixiong
name: Baldwin, Jon Kevin
name: Misra, Amit
name: Mara, Nathan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: III–V and other binary octet semiconductors often take two phase forms—wurtzite (wz) and zinc blende (zb) crystal structures—with distinct functional performance at room temperature. Here, taking AlN as a representative III–V compound, we investigate how to control the synthesized phase structure to either wz or zb phase by tuning the interfacial strain. By applying in situ mechanical tests at atomic scale in a transmission electron microscope, we observed the reversible phase transformation from zb to wz, and characterized the transition path—the collective glide of Shockley partials on every two {111} planes of the zb AlN. IMPACT STATEMENT The innovation of this paper is that a new type of plastic-deformation-driven reversible phase transition in AlN has been captured at atomic scale.
title: Influence of Lubrication Systems on the Fatigue Strength of Bolted Joints
Creators: name: Kraemer, Fabian
name: Stähler, Michael
name: Klein, Marcus
name: Oechsner, Matthias
Publisher: name: MDPI
Year: 2022

description: The fatigue behavior of bolted joints is critical to failure for many applications due to the high notch effect. Among other parameters, the lifetime is based on the influence of the surface system, consisting of corrosion protection and lubricant. With the intention of considering the surface system in the design and dimensioning process of bolted joints, experimental investigations are carried out systematically for an exemplary selected basecoat and various lubricant systems. The basis is given by fatigue tests supported by selected methods of material analysis for the fractographic evaluation. A reproducible method to determine the crack initiation as well as the crack propagation is developed and used for the evaluation of lubricant systems. Defined damage can be reproducibly assigned on the basis of a critical frequency change rate of the resonance test machine. A high durability of the friction in the load-bearing contact (e.g., greases) reduces the stress and delays the crack initiation. Lubricants which are able to creep (e.g., oil) slow down the crack propagation and increase the lifetime, which is proved by a higher number of cycles to failure and an increased fatigue strength.
Four new monoterpenoids from an endophytic fungus Periconia sp. F-31
Creators: name: Liu, Ji-Mei
name: Zhang, De-Wu
name: Du, Wen-Yu
name: Zhang, Min
name: Zhao, Jin-Lian
name: Chen, Ri-Dao
name: Xie, Ke-bo
name: Dai, Jun-Gui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Five monoterpenoids were isolated from the endophytic fungus Periconia sp. F-31, including three new carene-type monoterpenoids, 2-carene-5,8-diol (1), 2-carene-8,10-diol (2), 2-carene-8-acetamide (3), one new menthene-type monoterpenoid 8-hydroxy-1,7-expoxy-2-menthene (4), and one known monoterpenoid anethofuran (5). The structures of all compounds were elucidated based on a comprehensive spectroscopic data analysis, electronic circular dichroism (ECD), and calculated ECD.
Three new amino acid derivatives from edible mushroom Pleurotus ostreatus
Creators: name: Lu, Xiao-Jie
name: Feng, Bao-Min
name: Chen, Shao-Fei
name: Zhao, Dan
name: Chen, Gang
name: Wang, Hai-Feng
name: Pei, Yue-Hu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Three new amino acid derivatives, oxalamido-L-phenylalanine methyl ester (1), oxalamido-L-leucine methyl ester (2), and lumichrome hydrolyzate (3), together with nine known compounds (4–12), were isolated from the solid culture of edible mushroom Pleurotus ostreatus. Their structures were elucidated on the basis of extensive spectroscopic analysis. The absolute configurations of 1 and 2 were established by the chiral synthesis and confirmed by circular dichroism (CD) analysis of their total synthesis products and natural isolates. All new compounds were evaluated for their antioxidant effects, antimicrobial activities, and cytotoxic activity. Compounds 1–3 showed weak antifungal activities against Candida albicans with minimum inhibitory concentration (MIC) value of 500 μg/ml.
BH-3. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: BH-3 drillhole record
Structural dynamics of plant-pollinator mutualistic networks
Creators: name: Lampo, Aniello
name: Palazzi, María J.
name: Borge-Holthoefer, Javier
name: Solé-Ribalta, Albert
Publisher: name: arXiv
Year: 2021
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: The discourse surrounding the structural organization of mutualistic interactions mostly revolves around modularity and nestedness. The former is known to enhance the stability of communities, while the latter is related to their feasibility, albeit compromising the stability. However, it has recently been shown that the joint emergence of these structures poses challenges that can eventually lead to limitations in the dynamic properties of mutualistic communities. We hypothesize that considering compound arrangements -- modules with internal nested organization -- can offer valuable insights in this debate. We analyze the temporal structural dynamics of 20 plant-pollinator interaction networks and observe large structural variability throughout the year. Compound structures are particularly prevalent during the peak of the pollination season, often coexisting with nested and modular arrangements in varying degrees. Motivated by these empirical findings, we synthetically investigate the dynamics of the structural patterns across two control parameters -- community size and connectance levels -- mimicking the progression of the pollination season. Our analysis reveals contrasting impacts on the stability and feasibility of these mutualistic communities. We characterize the consistent relationship between network structure and stability, which follows a monotonic pattern. But, in terms of feasibility, we observe non-linear relationships. Compound structures exhibit a favorable balance between stability and feasibility, particularly in mid-sized ecological communities, suggesting they may effectively navigate the simultaneous requirements of stability and feasibility. These findings may indicate that the assembly process of mutualistic communities is driven by a delicate balance among multiple properties, rather than the dominance of a single one.
PD-20. Unravelling an allochthonous, subaqueously deposited volcanic–epiclastic to subaerial andesitic lava assemblage in Hong Kong: age, stratigraphy and provenance studies of the Middle Jurassic Tuen Mun Formation
Creators: name: R. J. Sewell
name: K. W. F. So
name: D. L. K. Tang
name: A. Carter
Publisher: name: Geological Society of London
Year: 2017
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: PD-20 drillhole record
Non-linear patterns in age-related DNA methylation may reflect CD4+ T cell differentiation
Creators: name: Johnson, Nicholas D.
name: Wiener, Howard W.
name: Smith, Alicia K.
name: Nishitani, Shota
name: Absher, Devin M.
name: Arnett, Donna K.
name: Aslibekyan, Stella
name: Conneely, Karen N.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: DNA methylation (DNAm) is an important epigenetic process involved in the regulation of gene expression. While many studies have identified thousands of loci associated with age, few have differentiated between linear and non-linear DNAm trends with age. Non-linear trends could indicate early- or late-life gene regulatory processes. Using data from the Illumina 450K array on 336 human peripheral blood samples, we identified 21 CpG sites that associated with age (P<1.03E-7) and exhibited changing rates of DNAm change with age (P<1.94E-6). For 2 of these CpG sites (cg07955995 and cg22285878), DNAm increased with age at an increasing rate, indicating that differential DNAm was greatest among elderly individuals. We observed significant replication for both CpG sites (P<5.0E-8) in a second set of peripheral blood samples. In 8 of 9 additional data sets comprising samples of monocytes, T cell subtypes, and brain tissue, we observed a pattern directionally consistent with DNAm increasing with age at an increasing rate, which was nominally significant in the 3 largest data sets (4.3E-15<P<0.039). cg07955995 and cg22285878 reside in the promoter region of KLF14, which encodes a protein involved in immune cell differentiation via the repression of FOXP3. These findings may suggest a possible role for cg07955995 and cg22285878 in immunosenescence.
A new polyketide glycoside from the rhizospheric Clonostachys rogersoniana associated with Panax notoginseng
Creators: name: Yin, Tian-Peng
name: Xing, Yun
name: Cai, Le
name: Yu, Jing
name: Luo, Ping
name: Ding, Zhong-Tao
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: A new polyketide glycoside rogerson A (1), along with two known compounds, rogerson B (2) and (22E)-5α,8α-epidioxyergosta-6,22-dien-3β-ol (3), was obtained from the solid fermentation of Clonostachys rogersoniana, which was isolated from the rhizosphere soil of Panax notoginseng. Rogerson B (2) was isolated for the first time from a natural source. Their structure was determined by extensive analyses of NMR and MS studies. Compounds 1 and 2 were tested for its cytotoxicity against five human cancer cell lines.
title: Application of Nanofluids in CO₂ Absorption: A Review
Creators: name: Aghel, Babak
name: Janati, Sara
name: Alobaid, Falah
name: Almoslh, Adel
name: Epple, Bernd
Publisher: name: MDPI
Year: 2022

description: The continuous release of CO₂ into the atmosphere as a major cause of increasing global warming has become a growing concern for the environment. Accordingly, CO₂ absorption through an approach with maximum absorption efficiency and minimum energy consumption is of paramount importance. Thanks to the emergence of nanotechnology and its unique advantages in various fields, a new approach was introduced using suspended particles in a base liquid (suspension) to increase CO₂ absorption. This review article addresses the performance of nanofluids, preparation methods, and their stability, which is one of the essential factors preventing sedimentation of nanofluids. This article aims to comprehensibly study the factors contributing to CO₂ absorption through nanofluids, which mainly addresses the role of the base liquids and the reason behind their selection.