cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Молодежь региона как субъект инновационного развития (на примере Астраханской области)
Creators: name: Каргаполова, Е. В.
name: Дулина, Н. В.
Publisher: name: Реноме
Year: 2019

description: В теоретическом плане показано, что сущность молодежи как субъекта инновационного развития состоит в создании и распространении новшеств, обладающих потребительной стоимостью – социальной полезностью. На основе результатов эмпирических исследований выявлены тенденции и проблемы формирования молодежи как субъекта инновационного развития конкретного российского региона – Астраханской области.
Ключевые слова: молодежь, инновация, инновационное развитие, субъект инновационного развития, регион.
Guidelines for constructing reusable domain ontologies
Creators: name: Annamalai, Muthukkaruppan
name: Sterling, Leon
Publisher: name: Swinburne
Year: 2024

description: The growing interest in ontologies is concomitant with the increasing use of agent systems in user environment. Ontologies have established themselves as schemas for encoding knowledge about a particular domain, which can be interpreted by both humans and agents to accomplish a task in cooperation. However, construction of the domain ontologies is a bottleneck, and planning towards reuse of domain ontologies is essential. Current methodologies concerned with ontology development have not dealt with explicit reuse of domain ontologies. This paper presents guidelines for systematic construction of reusable domain ontologies. A purpose-driven approach has been adopted. The guidelines have been used for constructing ontologies in the Experimental High-Energy Physics domain.
Participant-reported effect of an Indigenous health continuing professional development initiative for specialists
Creators: name: Barnabe, Cheryl
name: Kherani, Raheem
name: Appleton, Tom
name: Umaefulam, Valerie
name: Henderson, Rita
name: Crowshoe, Lynden
Publisher: name: BioMed Central
Year: 2021

description: Background: Health outcomes of Indigenous patients are impacted by culturally unsafe specialty care environments. The ‘Educating for Equity (E4E)’ program is a continuing professional development (CPD) intervention which incorporates skill-based teaching to improve Indigenous patient experiences and outcomes in healthcare interactions. Methods: The E4E program was delivered to rheumatologists in two phases, each delivered as experiential learning workshops where participants engaged with and applied course content within an interactive format focusing on real-time feedback. The phase 1 workshop focused on skill development of E4E Framework concepts and principles. Phase 2 concentrated on building capacity for teaching of E4E content. Evaluation of the program’s effectiveness was through longitudinal responses to the Social Cultural Confidence in Care Survey (SCCCS), self-reported strategies employed to address social issues and improve therapeutic relationships, engagement with teaching others, and satisfaction with the program. Results: Two cohorts of participants have participated in the program (n = 24 Phase 1, n = 10 Phase 2). For participants completing both phases of training, statistically significant improvements were observed in exploring social factors with patients, gaining knowledge and skills related to cultural aspects of care, improved communication and relationship building, and reflections on held stereotypes. Strategies to address social issues and build therapeutic relationships remained consistent throughout participation, while the training enhanced exploration and confidence to ask about cultural and traditional practices, and stronger communication strategies for exploring beliefs, expectations, social barriers, and residential school impacts on health. Participants reported feeling prepared to teach Indigenous health concepts to others and subsequently lead teaching with residents, fellows, and allied health professionals. Satisfaction with the delivery and content of the workshops was high, and participants valued interactions with peers in learning. Conclusions: This CPD intervention had a beneficial impact on self-reported confidence and enhanced practice strategies to engage with Indigenous patients.
title: Учет интересов досуговых предпочтений подростков, имеющих девиантное поведение, в работе подростково-молодежных клубов
Creators: name: Насибуллин, И. Р.
name: Редюк, А. Л.
Publisher: name: Реноме
Year: 2019

description: В статье рассматривается актуальность решения проблемы организации досуга подростков, имеющих девиантное поведение, на базе подростково-молодежных клубов Санкт-Петербурга с учетом выявленных досуговых предпочтений.
Ключевые слова: подростки, девиантное поведение, социальные нормы, досуг, досуговые предпочтения, подростково-молодежные клубы.
title: Социальная системная инженерия в развитии инновационной активности молодежи регионов России
Creators: name: Лавренюк, Н. М.
Publisher: name: Реноме
Year: 2019

description: Как отмечают ученые (П.А. Сорокин, И.В. Бестужев-Лада, И.В. Наместникова, Л.Н. Гумилев и др.), в развитии общества прослеживаются две силы: первая стремится к равновесию и отталкивает идеи с потенциалом стать инновациями, а вторая – преобразовательная, новаторская сила, связанная с личностным поиском постоянного усовершенствования. Поиск новых «идеальных целей» провоцирует молодежь на активность в процессе занятия своего места в социальной структуре. Системная социальная инженерия позволит в региональном разрезе России оценить возможности и ограничения инновационной активности молодежи.
Ключевые слова: молодежь регионов, инновационная активность, развитие, социальная системная инженерия.
Modellfreies Lernen optimaler zeitdiskreter Regelungsstrategien für Fertigungsprozesse mit endlichem Zeithorizont
Creators: name: Dornheim, Johannes
Publisher: name: KIT Scientific Publishing
Year: 2022
Subjects: Maschinelles Lernen
Entscheidungsoptimierung
Bestärkendes Lernen
Prozesspfadoptimierung
Optimale Regelung
machine learning
reinforcement learning
decision optimization
process optimization
optimal control

description: Die Qualität und Leistungsfähigkeit von Bauteilen wird wesentlich von der Ausführung der beteiligten Fertigungsprozesse bestimmt. Das Prozessergebnis hängt -- neben dem Anfangszustand des Bauteils und des Prozesses -- von dem Prozessverlauf ab. Bei vielen Fertigungsprozessen kann der Prozessverlauf durch zeitlich veränderliche Stellgrößen maßgeblich bestimmt werden. Diese Arbeit behandelt Methoden zur Optimierung dieser zeitveränderlichen Größen unter schwankenden Prozessbedingungen.
Speculation, liquidity provision and responsibility in agricultural commodity futures
Creators: name: Koch, Sebastian
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2024
Subjects: 332: Finanzwirtschaft

description: In the early 2000s, commodity futures attracted significant investment as a new asset class, particularly through index speculation. This financialisation of the commodity markets led to a significant inflow of capital and was associated with increased price volatility. The substantial amount of investment has caused concern and called speculation into question. In contrast, the importance of speculation in the markets is emphasised by the provision of liquidity and risk sharing. However, they also act as demanders of liquidity, which explains a large part of short-term trading and is associated with a premium.
The aim of this bachelor thesis is to analyse the short-term behaviour of market participants, the provision of liquidity and its influence on futures prices on the agricultural commodity markets. Based on the work of Kang et al. (2020), the predictability of positioning data as well as future returns and their correlations are analysed. Finally, the results are placed in the context of the responsibility of speculation. The paper focuses on the period from June 2006 to March 2024 and uses data from 13 agricultural commodity futures from the Supplemental Report of the Commodity Futures Trading Commission (CFTC). The analysis is based on weekly position data from the CFTC and uses Fama-MacBeth and panel regressions to investigate the relationship between position data and futures returns.
Empirical evidence indicates that hedgers act as contrarians to speculators and index investors. The positive correlation between position changes and past futures returns suggests that speculators are momentum traders. In contrast to previous literature, index investors also appear to show a momentum tilt, albeit to a much lesser extent, which is consistent with their strategy as passive investors. Additionally, significant correlations have been found between position changes and subsequent futures returns. The results indicate that commercial traders benefit from the provision of liquidity, while speculative traders and index investors pay for immediate liquidity with a premium that is reflected in the underperformance of the futures they buy.
In summary, financialisation has brought in index investors who also generate a premium for immediate liquidity. The provision of liquidity to speculators and index investors leads to short-term trading fluctuations, which are a significant factor influencing futures prices. This short-term trading exceeds the pure need for hedging and would be considered excessive and unjustifiable according to the definition in the literature.
The CFTC's expanded disclosure of data on index investors could allow for a more detailed examination of index trading. Future research could examine the actual contribution of index investors to the functioning of commodity futures markets.
title: Инновационные подходы в экологическом воспитании молодежи в Тульской области
Creators: name: Мосин, В. И.
Publisher: name: Реноме
Year: 2019

description: От экологической грамотности населения в наше время зависит очень многое. Развитие экологического образования и воспитания является на сегодняшний день делом общенародным. Особенно важно повышать экологическую грамотность молодого поколения. В различных регионах России эта задача решается. В Тульской области есть свои особенности и направления в этой сфере.
Ключевые слова: экологическое воспитание, экологическое образование, молодежь, сельское хозяйство, студенты, экологическая культура.
Klimarisiken analysieren: mehr als eine Pflicht : Berichterstattung über Klimabelange
Creators: name: Tobler, Kaspar
name: Brown, Samuel
name: Michel, Clotaire
Publisher: name: Swiss Association for Quality
Year: 2024
Subjects: 363: Umwelt- und Sicherheitsprobleme
658.408: Sicherheitsmanagement, Umweltmanagement

description: Der Gesetzgeber hat für gewisse Unternehmen die Berichterstattung über Klimabelange zur Pflicht erklärt. Doch die Beurteilung der Risiken des Klimawandels sollte nicht nur als Pflicht verstanden werden – es lohnt sich für alle Unternehmen, für kommende Veränderungen gerüstet zu sein.
Organisationsformen des Facility Managements in Akutspitälern
Creators: name: Merkle, Thorsten
name: Plüss, Till
Publisher: name: Balmer
Year: 2024
Subjects: Facility Management
Akutspital
Organisation
362.11: Krankenhäuser und verwandte Einrichtungen
658.2: Facility Management

description: Mit Blick auf zukünftige Entwicklungen und Veränderungen sind Spitäler auf eine passende Aufbauorganisation angewiesen. Die Bezeichnungen und Organisation des Facility Managements (FM) in Schweizer Spitälern zeigt sich äusserst heterogen. Ein Projekt der Kompetenzgruppe Hospitality & Service Management des Instituts für Facility Management (IFM) der Zürcher Hochschule für Angewandte Wissenschaften (ZHAW) ging den Fragen nach, wo das FM in Schweizer Spitälern verortet ist, welche Führungsspannen es aufweist und welche Bezeichnungen für die verschiedenen Abteilungen verwendet werden.
title: Предпринимательский потенциал молодежи и возможные пути его активизации: опыт регионов Центрального Черноземья
Creators: name: Пасовец, Ю. М.
Publisher: name: Реноме
Year: 2019

description: В работе предпринимается попытка выявить и охарактеризовать установки молодых людей на самозанятость и предпринимательскую деятельность как показатели ее предпринимательского потенциала на материалах Курской области. В контексте определения возможностей активизации предпринимательской инициативы молодежи рассматривается региональная система поддержки малых и средних предпринимателей, анализируются преимущества организации такой поддержки в других регионах Центрального Черноземья.
Ключевые слова: молодежь, молодежное предпринимательство, предпринимательский потенциал, малый и средний бизнес, регион.
Study protocol: Activity patterns and stress – prognostic factors for pain persistence and disability in acute neck pain. A one year prospective inception cohort study
Creators: name: Morf, Rita
name: Reicherzer, Leah
name: Degenfellner, Jürgen
name: Ernst, Markus
name: Pfeiffer, Fabian
name: Luomajoki, Hannu
name: Hasenbring,  Monika
name: Hotz-Boendermaker, Sabina
Publisher: name: OSF
Year: 2024
Subjects: Neck pain
Activity pattern
Stress
Pain
Disability
616.7: Krankheiten des Bewegungsapparates und Orthopädie

description: Background: Neck pain (NP) is a significant health problem that can lead to pain persistence. Identifying prognostic factors for pain persistence in an acute NP sample might assist in alleviating prolonged pain and disability. Biopsychosocial and clinical factors appear to be adverse solid prognostic factors. Among them, avoidance and overactivity mediate pain persistence and disability. Stress plays a central role in this context, intricately interlinking with persistent pain. Both pain and stress are intricately interconnected processes, serving as adaptive mechanisms to protect the organism from harm. However, in cases of persistent pain, it can be seen as a form of stress overload, indicating a close relationship and the potential for an allostatic overload of the body and brain. Nevertheless, stress and activity patterns such as avoidance and overactivity have yet to be studied as prognostic factors for pain persistence states over one year in subjects with acute NP. Methods: This longitudinal inception cohort study recruits subjects with acute NP (<4 weeks since the onset of pain) aged 18-65 years in clinical praxis, hospitals, and universities. Activity patterns (Avoidance-Endurance-Fast Screening (AE-FS)) and stress (Stress and Coping Inventory (SCI)) are collected at four different time points. Additionally, hair cortisol concentrations (HCC) are measured to assess stress levels objectively. An online pain diary is maintained, providing information on the progression of pain over a year. In the initial phase, the prevalence of baseline activity patterns and HCC levels are determined using a cross-sectional design. As a subsequent step, the pain course over one year is observed. A linear mixed regression model calculates if activity patterns, stress, and pain are prognostic factors for persistent pain and disability at different time points. Discussion: To the best of our knowledge, this study represents the first investigation of activity patterns in acute NP and if activity patterns, stress, and pain are prognostic factors for persistent pain and disability in acute NP at different time points over one year.
Organisational performance: knowledge management adding value to measurement systems
Creators: name: Kloot, Louise
name: Lasky, Barbara
Publisher: name: Swinburne
Year: 2024

description: The concept of performance management is usually understood as a holistic, integrated performance evaluation method that is linked to the organisation's strategy and objectives, and includes strategy planning, performance standards, performance measurement and evah.tation, and at the individual level, training and development for managers and staff Although organisation performance is largely measured in financial terms, other aspects of it such as organisation learning, knowledge management, growth and innovation are now starting to be addressed. This paper attempts to integrate the concepts of knowledge management, organisation learning and performance measurement in a strategic context.
An Introductory Lecture Course on Solid-State NMR Spectroscopy
Creators: name: Berger, Stefan
Publisher: name: figshare
Year: 2022
Subjects: NMR Spectroscopy

description: Table of Contents Preface 1. Contents 2. General Books and Review Articles Lesson I  1. Introduction 2. Types of Solid Materials 3. Solid-state NMR parameters Lesson II  Equipment and Basic Adjustments for Solid-State NMR Spectroscopy 1. The Magnet 2. The Probe 3. Shimming Solid-State Probe-Heads 4. Adjusting the Magic Angle Lesson III  13C NMR in the Solid-State 1. Relaxation and Molecular Mobility 2. The Hartmann-Hahn Condition 3. The CP/MAS Experiment 4. The Bruker CP Programme Lesson IV  Chemical Shift Anisotropy-I 1. Introduction 2. The IUPAC Chemical Shift Anisotropy Convention 3. The Herzberg-Berger Convention 4. The Haeberlen Convention 5. Chemical Shift Anisotropy of Benzene and Phenyllithium 6. The Axial Symmetry of the Chemical Shift Anisotropy 7. Chemical Shift Anisotropy from Cross Relaxation Rates Lesson V Chemical Shift Anisotropy-II 1. Moment Analysis of Solid-State NMR Spectra 2. Measurement on Single Crystals 3. The Different Coordinate Systems 4. Powder Crystallography Lesson VI  Chemical Shift Anisotropy III 1. Suppression of Spinning Side Bands 2. Suppression of Non Quarternary Signals (NQS) Lesson VII  Applications in Organic Chemistry 1. The Carbonyl Group in Acids and Ketones 2. Ethene and Ethyne 3. Aromatic Compounds 4. Carbonium Ions Lesson VIII  Advanced Techniques 1. Polymorphism 2. Rotational Resonance 3. REDOR Lesson IX  Solid-State Proton NMR Spectra 1. Dipolar coupling 2. CRAMPS 3. Applications Lesson X  Quadrupolar Nuclei in Solid State NMR 1. Introduction 2. Basic Physics 3. Multiple Quantum Magic angle Spinning MQMAS 4. Double Rotation 5. Deuterium NMR Lesson XI  Mixed Applications 1. Organometallics 2. Reaction Control 3. Electrochemistry 4. High Resolution MAS NMR Spectroscopy Lesson XII  2D NMR Spectroscopy in the Solid State I 1. Introduction 2. C, H Correlation 3. Correlation of Chemical Shifts with the Signal Anisotropy 4. D-Resolved 2D Spectroscopy Lesson XIII  2D NMR Spectroscopy in the Solid State II 5. 2D NMR Assignment Experiments for Peptides and Proteins 6. Double Quantum Spectroscopy 7. Dipolar-Assisted Rotational Resonance DARR 8. Solid-State INADEQUATE Lesson XIV  Proton Based 3D Methods for Peptides and Proteins 1. Hydrogen Bonds 2. Amyloid-β Peptides 3. Special Techniques 4. Ultra-Highfield NMR in the Solid State XV Practical Exercises XVI Solutions for the Assignments
title: Стратегии повышения самоуправленческой активности молодежи региональными властями на примере Новосибирской области
Creators: name: Афанасьева, Ю. А.
Publisher: name: Реноме
Year: 2019

description: Органами государственной власти молодежь часто позиционируется, как двигатель социально-экономического прогресса страны. Утверждается приоритетность развития молодежной политики как в целом по стране, так и на уровне отдельных регионов. Однако реальное влияние государственной политики на активность молодежи в самоуправлении остается нераскрытым. В связи с этим, основной целью данной работы является анализ реализации молодежной политики в Новосибирской области и обзор существующих способов оценки эффективности внедрения механизмов развития молодежной политики для дальнейшего совершенствования государственной регуляции в данной сфере.
Ключевые слова: молодежь, молодежная политика, самоуправление.
Gender modifies the effect of body mass index on lung function decline in mild-to-moderate COPD patients: a pooled analysis
Creators: name: Chen, Wenjia
name: Sadatsafavi, Mohsen
name: FitzGerald, J. M.
name: Lynd, Larry D.
name: Sin, Don
Publisher: name: BioMed Central
Year: 2021

description: Background: Low body weight is associated with poor prognosis in patients with chronic obstructive pulmonary disease (COPD). However, it is not known whether gender modifies this relationship. Methods: We pooled data of 8686 COPD patients from 7 studies with a median length of 36-months of follow up. Using a longitudinal natural cubic spline regression model, we examined the dose–response relationship between body mass index (BMI) and the rate of decline in forced expiratory volume in one second (FEV₁) in patients with GOLD 1 and 2 disease, stratified by gender and adjusted for age, smoking status, and cohort effects. Results: There was an inverse linear relationship between BMI and the rate of FEV1 decline in GOLD Grades 1 and 2, which was modified by gender (p < 0.001). In male patients, an increase of BMI by 1 kg/m² reduced FEV₁ decline by 1.05 mL/year (95% CI 0.96, 1.14). However, in female patients, BMI status did not have a clinically meaningful impact on FEV1 decline: an increase of baseline BMI by 1 kg/m2 reduced FEV₁ decline by 0.16 ml/year (95% CI 0.11, 0.21). These gender-modified relationships were similar between GOLD 1 and 2 patients, and between current and former smokers. Conclusion: In mild to moderate COPD, higher BMI was associated with a less rapid decline of FEV1 in male patients whereas this association was minimal in females patients. This gender-specific BMI effect was independent of COPD severity and smoking status.
A 3D printed bio-hybrid optical skin model for light-skin interactions
Creators: name: Bajrami, Dardan
name: Hammer, Tobias
name: Spano, Fabrizio
name: Wei, Kongchang
name: Bonmarin, Mathias
name: Rossi, René
Publisher: name: ZHAW Zurich University of Applied Sciences
Year: 2024
Subjects: Biomedicine
Skin
3D Print
Model
Simulation
610.28: Biomedizin, Biomedizinische Technik

description: Skin models are essential tools in biomedical research, enabling the study of human skin structure, function, and interaction with external stimuli. Optical skin models in particular, have been valuable for exploring light-based biomedical applications such as imaging and laser treatments. However, current models have problems in replicating the complex interactions between light, skin, and living cells, especially when studying biological responses to optical stimuli.
This project addresses these limitations by developing a 3D-printed bio-hybrid skin model that mimics both the optical and biological properties of human skin. By combining an optically characterized epidermis with a hydrogel-based dermis structure, we aim to accurately simulate the light interactions with skin appendages, such as hair follicles, while integrating living cells to evaluate biological responses. This model provides a more comprehensive platform for investigating photothermal therapies and other light-based skin treatments.
title: Bioinformatic and biochemical characterization of arabidopsis thaliana protein nch1 and links to plant immunity
Creators: name: Salmirinne, Irni Onerva
Publisher: name: University of Glasgow
Year: 2022

description: NCH1 (NRL PROTEIN FOR CHLOROPLAST MOVEMENT 1) is a plant protein postulated to play a role in plant immunity, in addition to being a component of the plant blue light signalling pathway directly downstream of the phototropin blue light receptors. Confocal microscopy of mCitrine-tagged NCH1 Arabidopsis lines and bifluorescence complementation (BiFC) experiments in Nicotiana benthamiana suggest that in its native state, Arabidopsis protein AtNCH1 exists as a dimer, therefore confirming the similar results reported previously in its potato ortholog StNRL1. AtNCH1 was also found to localize at the plasma membrane both in the dark and after blue light treatment both in transgenic Arabidopsis hypocotyls and in the transient Nicotiana benthamiana expression system. Preliminary confocal microscopy studies on the putative phosphorylation-deficient variant, NCH1S602A-S604A, also exhibited similar localization in the plasma membrane in N. benthamiana. As it was hypothesised that NCH1 could play a role in Arabidopsis immunity against the hemibiotrophic bacterium Pseudomonas syringae pv. tomato DC3000 (Pst DC3000), flood assay data suggested that double mutant nch1-1/rpt2-3 plants showed inconclusive differences in impairment in immunity against Pst DC3000 in comparison to the wild type Col-0 plants. Further perspectives to the role of NCH1 in plant immunity include the determination of the phosphorylation state, and the roles of potential NCH1 interacting partners, including potential hetero interactions with NRL family proteins, on Arabidopsis immunity.
title: Социокультурные основания реализации молодежной политики в регионах Центрального Черноземья
Creators: name: Васильченко, Д. Д.
Publisher: name: Реноме
Year: 2019

description: В статье изложены проблемные аспекты реализации в регионах Центрального Черноземья молодежной политики, ориентированной на активизацию участия молодежи в социально-экономической и политической деятельности. Структурированы основные составляющие механизма реализации молодежной политики в макрорегионе. Выявлены интегративные факторы, способствующие развитию потенциала молодежи. Определены приоритетные направления реализации государственной молодежной политики в регионах Центрального Черноземья.
Ключевые слова: молодежь, государство, регион, молодежная политика, Центральное Черноземье, гражданское общество.
Thoracic Surgeon Impressions of the Impact of the COVID-19 Pandemic on Lung Cancer Care—Lessons from the First Wave in Canada
Creators: name: Hilzenrat, Roy A.
name: Deen, Shaun A.
name: Yee, John
name: Grant, Kyle A.
name: Ashrafi, Ahmad S.
name: Coughlin, Shaun
name: McGuire, Anna L.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2021

description: Background: COVID-19 has invariably changed the way lung cancer surgical care is provided in Canada. Despite relevant management guidelines, the way in which cancer care has been affected has yet to be described for thoracic surgical populations. Routine lung cancer physiologic and staging assessments are unique in that they are droplet producing and aerosolizing procedures. Our objective was to quantify the effect of the COVID-19 pandemic on surgical lung cancer care as perceived by practicing thoracic surgeons during the first wave of the pandemic in Canada. Methods: An electronic survey was distributed to members of the Canadian Association of Thoracic Surgeons. The survey was designed to determine surgeon perception of lung cancer preoperative care during the Canadian pandemic-instilled period of resource reallocation compared to standard care. Planned analyses were exploratory in nature; with count and frequency distributions of responses quantified. Results: Fifty-three thoracic surgeons completed the survey. Responses were collected from all Canadian provinces. Little change in access to preoperative imaging was noted. However, a significant decrease in access to lung function and bronchoscopy testing occurred. Pulmonary surgery was perceived to be lengthier with reduced operating theater availability. Despite decreased OR access, only 40% of surgeons were aware of respective institutional mitigation strategies. Summary: The COVID-19 pandemic has had an impact on standard lung cancer care preoperative workup. Further inquiry using institutional data is warranted to quantify its impact on cancer patient outcomes. Assessing the extent and effects of newly present barriers to standard lung cancer care is essential in forming appropriate mitigation strategies and planning for future pandemic waves.
Amtliche Mitteilungen der Technischen Universität Dortmund Nr.14/2022
Creators: name: (:Unkn) Unknown
Publisher: name: Technische Universität Dortmund
Year: 2022
Subjects: subject: 080

description: 2. Ordnung zur Änderung der Prüfungsordnung für den Bachelorstudiengang Data Science der Fakultät Statistik unter Beteiligung der Fakultät für Mathematik und der Fakultät für Informatik an der Technischen Universität Dortmund vom 5. Mai 2022
description: 2. Ordnung zur Änderung der Prüfungsordnung für den Masterstudiengang Data Science der Fakultät Statistik unter Beteiligung der Fakultät für Mathematik und der Fakultät für Informatik an der Technischen Universität Dortmund vom 5. Mai 2022
description: Amtliche Mitteilungen der Technischen Universität Dortmund;2022; 14
Regioselective partial hydrogenation and deuteration of tetracyclic (Hetero)aromatic systems using a simple heterogeneous catalyst
Creators: name: A. Kehoe, Roberta
name: Lowry, Amy
name: Light, Mark E.
name: Jones, David
J.
name: Byrne, Peter
A.
name: McGlacken, Gerard P.
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences

description: The introduction of added ‘3-dimensionality’ through late-stage functionalisation of extended (hetero)aromatic systems is a powerful synthetic approach. The abundance of starting materials and cross-coupling methodologies to access the precursors allows for highly diverse products. Subsequent selective partial reduction can alter the core structure in a manner of interest to medicinal chemists. Herein, we describe the precise, partial reduction of multicyclic heteroaromatic systems using a simple heterogeneous catalyst. The approach can be extended to introduce deuterium (again at late-stage). Excellent yields can be obtained using simple reaction conditions.
title: Κληρονομικός καρκίνος του μαστού: ο ρόλος του γονιδιακού ελέγχου
title: Hereditary breast cancer: the role of gene control
titleType: AlternativeTitle
Creators: name: Ξανθού, Χρυσοβαλάντα
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2022
Subjects: Καρκίνος του μαστού
Γονιδιακός έλεγχος

description: Ο καρκίνος του μαστού, είναι μία από τις πιο συχνές κακοήθειες που ανιχνεύονται σε γυναίκες, καθώς και η πρώτη αιτία θανάτου στο γυναικείο φύλο, παγκοσμίως. Περίπου το 5-10% των περιστατικών καρκίνου του μαστού οφείλεται σε μεταλλάξεις στα γονίδια BRCA1 και BRCA2. Ωστόσο υπάρχουν και μεταλλάξεις σε άλλα γονίδια που οδηγούν σε καρκίνο του μαστού. Τα γονίδια αυτά ταξινομούνται σε γονίδια υψηλής , μέτριας και χαμηλής διεισδυτικότητας με βάση τον κίνδυνο εμφάνισης καρκίνου. Στα γονίδια υψηλής διεισδυτικότητας ανήκουν τα BRCA1, BRCA2, PTEN, TP53 και STK11.Στα γονίδια μέτριας διεισδυτικότητας περιλαμβάνονται τα PALB2, ATM, CHEK2 και BARD1. Επομένως είναι απαραίτητη η ταυτοποίηση των υπεύθυνων γονιδίων, ώστε να δοθεί η κατάλληλη θεραπεία σε άτομα που νοσούν ή να αναπτυχθούν στρατηγικές πρόληψης στα άτομα υψηλού κινδύνου. Επιπλέον είναι σημαντικό να περιοριστούν οι περιβαλλοντικοί παράγοντες κινδύνου ώστε να μειωθούν τα περιστατικά καρκίνου του μαστού. Στην ταυτοποίηση των υπεύθυνων γονιδίων, καθοριστικό ρόλο έχει η γενετική συμβουλευτική πριν και μετά την διάγνωση. Αρχικά γίνεται λήψη οικογενειακού και ατομικού ιστορικού, ώστε να προσδιοριστεί η πιθανότητα ύπαρξης κάποιας μετάλλαξης και έπειτα ενημέρωση για το κόστος, τα πιθανά αποτελέσματα των δοκιμών, την επιτήρηση , την πρόληψη και την ψυχοκοινωνική υποστήριξη. Κατά τον γενετικό έλεγχο ανιχνεύονται 5 τύποι μεταλλάξεων: καλοήθεις, πιθανώς καλοήθεις, αβέβαιης σημασίας, πιθανώς παθογόνες και παθογόνες. Η ερμηνεία των αποτελεσμάτων σε πολλές περιπτώσεις καθίσταται περίπλοκη και χρειάζεται περαιτέρω διερεύνηση, ιδιαίτερα στις μεταλλάξεις αβέβαιης σημασίας. Εκτός από αυτό, ο γενετικός έλεγχος παρουσιάζει επιπλέον εμπόδια που χρήζουν αντιμετώπισης, όπως η έλλειψη συστάσεων για την διαχείριση των αποτελεσμάτων, οι αποκλίσεις μεταξύ των εργαστηρίων και ο μειωμένος αριθμός γενετικών συμβούλων. Παρ’ όλα αυτά υπάρχουν ενθαρρυντικές έρευνες όσον αφορά την πρόληψη και την θεραπεία. Η προληπτική θεραπεία και μαστεκτομή καθώς και οι αναστολείς PARP, σε συνδυασμό με τον τακτικό έλεγχο, έχει αποδειχθεί ότι μειώνουν σημαντικά τον κίνδυνο για καρκίνο του μαστού.
title: Значение коммуникативных навыков студентов в освоении самоуправленческих компетенций
Creators: name: Галынская, Ю. С.
Publisher: name: Реноме
Year: 2019

description: В статье рассматривается роль коммуникативной компетентности в подготовке студентов к самоуправленческой деятельности. Предлагается модель формирования коммуникативной компетентности. Рассмотрены результаты эмпирического исследования уровня коммуникативной компетентности студентов колледжа при Сибирском университете потребительской кооперации в 2018–2019 гг. Автор показывает эффективность использования сказкотерапии и интерактивных образовательных технологий для приобретения обучающимися коммуникативных навыков.
Ключевые слова: коммуникативная компетентность, тренинг, сказкотерапия, интерактивные образовательные технологии, команда, самоуправление.
Leitfaden zur umweltfreundlichen öffentlichen Beschaffung: Emissionsarme Bodenbelagsklebstoffe und andere Verlegewerkstoffe
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2022
Subjects: subject: Öffentliche Beschaffung
subject: Umweltfreundliche Beschaffung
subject: Bodenbelagsklebstoffe
subject: Verlegewerkstoffe
subject: Wirtschaft | Konsum

description: Mit Verlegewerkstoffen wie Fliesenklebern oder Spachtelmassen werden Untergründe für Bodenbeläge behandelt, um diese großflächig in Innenräumen zu verkleben. Aus Umwelt- und Gesundheitssicht sollten sie möglichst emissionsarm sein. Dieser Leitfaden hilft bei der Beschaffung von Produkten, die die Kriterien des Blauen Engels für emissionsarme Bodenbelagsklebstoffe und andere Verlegewerkstoffe (DE-UZ 113, Ausgabe Januar 2019) erfüllen. Quelle: www.umweltbundesamt.de
description: Mit Verlegewerkstoffen wie Fliesenklebern oder Spachtelmassen werden Untergründe für Bodenbeläge behandelt, um diese großflächig in Innenräumen zu verkleben. Aus Umwelt- und Gesundheitssicht sollten sie möglichst emissionsarm sein.Dieser Leitfaden hilft bei der Beschaffung von Produkten, die die Kriterien des Blauen Engels für emissionsarme Bodenbelagsklebstoffe und andere Verlegewerkstoffe (DE-UZ 113, Ausgabe Januar 2019) erfüllen.
Data for Global Estimates of the Extent and Production of Macroalgal Forests
Creators: name: Duarte, Carlos M
name: Assis, Jorge
name: Pessarrodona, Albert
name: Krause-Jensen, Dorte
Publisher: name: figshare
Year: 2022
Subjects: subject: 60202 Community Ecology (excl. Invasive Species Ecology)
subject: FOS: Biological sciences
subject: 50104 Landscape Ecology
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 50301 Carbon Sequestration Science
subject: FOS: Agriculture, forestry and fisheries
subject: 49999 Earth Sciences not elsewhere classified

description: This is the data used for Duarte et al. 2021: Global estimates of the extent and production of macroalgal layers. It includes the predictive habitat layers as well as the NPP dataset and scripts to estimate global NPP fluxes.
title: Управление региональным развитием: структуры, субъекты, потенциалы
Creators: name: Баранец, С. Н.
Publisher: name: Реноме
Year: 2019

description: В статье рассмотрены проблемы становления современного российского стиля управления региональным развитием. В ходе обсуждения проблем регионалистики и процессов обретения устойчивости внутреннего обустройства субъекта Федерации показаны основные элементы и структуры управленческих взаимодействий. Составной частью располагаемых региональных ресурсов выступают природные, социокультурные и организационные возможности регионального сообщества, в процессе формирования которого существенную роль призваны сыграть когорты молодых граждан. Их способности придавать региональному интересу существенную инновационную составляющую на данный момент ограниченны. Предложены способы активизации этой инновационной составляющей на примере развития политического потенциала местных молодежных лидеров.
Ключевые слова: регионы, политика, субъектность, молодежь, потенциал, управление, инновации.
ATS-STEM Lopullinen toimeenpaneva tutkimusraportti
Creators: name: Fernández-Morante, Carmen
name: Fernández de la Iglesia, J. Carmen
name: Cebreiro López, Beatriz
name: Casal Otero, Lorena
name: Latorre Ruiz, Enrique
name: Mareque-León, Francisco
Publisher: name: Zenodo
Year: 2022
Subjects: Evaluative research
Globalized teaching
Interdisciplinary teaching
Educational innovation
STEM education

description: This executive research design has been developed within the framework of work package 5 of the European project "Assessment of Transversal Skills in STEM (ATS-STEM) and has been carried out by the educational technology group of the University of Santiago de Compostela (http://tecnoeduc.es) and are available from the project website: https://www.atsstem.eu/resources/ It contains the executive summary of the research report produced under work package 5 of the project. It reports in abbreviated form on the evaluative research conducted and the results obtained following the pilot conducted in schools in 7 European countries. This publication is complemented by the full transnational research report carried out within the framework of the project which will be disseminated through publications in scientific journals of impact. For more information, refer to carmen.morante@usc.es
Elevation perception: phantom images in the vertical hemi-sphere
Creators: name: Barbour, Jim
Publisher: name: Swinburne
Year: 2024

description: Listening experiments were conducted to investigate the relationship between loudspeaker locations in the vertical hemi-sphere and elevation perception. Using a standard five-channel reproduction system and two loudspeakers positioned over the vertical hemi-sphere, phantom images were created using inter-channel amplitude differences between loudspeaker pairs. The results were evaluated and used to suggest the most useful loudspeaker locations. This paper describes the methodology employed, presents the test results, makes some initial conclusions and suggests possible further areas for investigation.
The SSH Open Marketplace Pelican
Creators: name: Robert, Paul
Publisher: name: Zenodo
Year: 2022

description: User Story resulting from the SSHOC'n Tell Challenge. Among the best practice of a Digital Humanities (DH) engineer, or researcher as well, is the urge to always be updated on the last technologies, discoveries or innovations. As we work on a domain in constant evolution, we need to be aware each day of publications made all around the world. But the large amount of publications available on various repositories all day and the difficulty to find articles and datasets related closely to my own topic of work is a pain. Automate topic-related publications and datasets gathering through API crawling of the SSH Open Marketplace and others platform solves greatly this problem: on the one hand references are gathered on a website in a database as a future reading, on the other hand a twitter bot increases serendipity by sharing all days some articles or datasets dedicated to a specific theme in one twitter’s timeline.
The COVID-19 Pandemic: Disproportionate Thrombotic Tendency and Management Recommendations
Creators: name: Karim, Sabina
name: Islam, Amin
name: Rafiq, Shafquat
name: Laher, Ismail
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2021

description: COVID-19 is an infectious disease caused by the SARS COV-2 virus. Patients with COVID-19 are susceptible to thrombosis due to excessive inflammation, platelet activation, endothelial dysfunction, and circulatory stasis, resulting in an increased risk of death due to associated coagulopathies. In addition, many patients receiving antithrombotic therapy for pre-existing thrombotic diseases can develop COVID-19, which can further complicate dose adjustment, choice and laboratory monitoring of antithrombotic treatment. This review summarizes the laboratory findings, the prohemostatic state, incidence of thromboembolic events and some potential therapeutic interventions of COVID-19 associated coagulopathy. We explore the roles of biomarkers of thrombosis and inflammation according to the severity of COVID-19. While therapeutic anticoagulation has been used empirically in some patients with severe COVID-19 but without thrombosis, it may be preferable to provide supportive care based on evidence-based randomized clinical trials. The likely lifting of travel restrictions will accelerate the spread of COVID-19, increasing morbidity and mortality across nations. Many individuals will continue to receive anticoagulation therapy regardless of their location, requiring on-going treatment with low-molecular weight heparin, vitamin K antagonist or direct-acting anticoagulants.
Provably Secure Public-Key Steganography Based on Admissible Encoding
Creators: name: Zhang, Xin
name: Chen, Kejiang
name: Zhao, Na
name: Zhang, Weiming
name: Yu, Nenghai
Publisher: name: arXiv
Year: 2025
Subjects: subject: Cryptography and Security (cs.CR)
subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: The technique of hiding secret messages within seemingly harmless covertext to evade examination by censors with rigorous security proofs is known as provably secure steganography (PSS). PSS evolves from symmetric key steganography to public-key steganography, functioning without the requirement of a pre-shared key and enabling the extension to multi-party covert communication and identity verification mechanisms. Recently, a public-key steganography method based on elliptic curves was proposed, which uses point compression to eliminate the algebraic structure of curve points. However, this method has strict requirements on the curve parameters and is only available on half of the points. To overcome these limitations, this paper proposes a more general elliptic curve public key steganography method based on admissible encoding. By applying the tensor square function to the known well-distributed encoding, we construct admissible encoding, which can create the pseudo-random public-key encryption function. The theoretical analysis and experimental results show that the proposed provable secure public-key steganography method can be deployed on all types of curves and utilize all points on the curve.
description: 16 pages, 3 figures
Triaxial test results of high-strength concrete subjected to cyclic loading
Creators: name: Lokuge, W. P.
name: Sanjayan, Jay
name: Setunge, S.
Publisher: name: Swinburne
Year: 2024

description: High-strength concrete (HSC) has highly desirable structural engineering properties, which can lead to significant cost savings in heavily loaded concrete structures. However, its use is limited by a concern regarding an increased brittleness compared to normal strength concrete (NSC), especially under complex multi-axial loading conditions. The issue of ductility is extremely important in structures subjected to earthquake loading conditions. In order to determine the lateral confinement required for a given level of ductility, the relationship between axial stress and lateral strain of confined HSC needs to be established. This paper describes a testing programme carried out to obtain the relationships between axial stress, axial strain and lateral strain for HSC under cyclic loading and subjected to constant lateral confining pressures. Compressive strengths of concrete tested were 40, 60, 80 and 100 MPa. Uniform confining pressures applied were 4, 8 and 12 MPa. The experimental results are presented and the effects of cyclic loading and confinement on the constitutive behaviour of HSC are described.
Microglia fighting for neurological and mental health : On the central nervous system frontline of COVID-19 pandemic
Creators: name: De Andrade, Elisa Gonçalves
name: Šimoncicová, Eva
name: Carrier, Micaël
name: Vecchiarelli, Haley A.
name: Robert, Marie-Ève
name: Tremblay, Marie-Ève (Neuroscientist)
Publisher: name: Frontiers
Year: 2021

description: Coronavirus disease 2019 (COVID-19) is marked by cardio-respiratory alterations, with increasing reports also indicating neurological and psychiatric symptoms in infected individuals. During COVID-19 pathology, the central nervous system (CNS) is possibly affected by direct severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invasion, exaggerated systemic inflammatory responses, or hypoxia. Psychosocial stress imposed by the pandemic further affects the CNS of COVID-19 patients, but also the non-infected population, potentially contributing to the emergence or exacerbation of various neurological or mental health disorders. Microglia are central players of the CNS homeostasis maintenance and inflammatory response that exert their crucial functions in coordination with other CNS cells. During homeostatic challenges to the brain parenchyma, microglia modify their density, morphology, and molecular signature, resulting in the adjustment of their functions. In this review, we discuss how microglia may be involved in the neuroprotective and neurotoxic responses against CNS insults deriving from COVID-19. We examine how these responses may explain, at least partially, the neurological and psychiatric manifestations reported in COVID-19 patients and the general population. Furthermore, we consider how microglia might contribute to increased CNS vulnerability in certain groups, such as aged individuals and people with pre-existing conditions.
title: Молодежные некоммерческие организации как потенциал инновационного развития региона
Creators: name: Лежебоков, А. А.
name: Сергодеева, Е. А.
Publisher: name: Реноме
Year: 2019

description: В работе рассматривается деятельность молодежных некоммерческих организаций Ставропольского края, проблематика их функционирования. Ставится вопрос о зависимости некоммерческих организаций от специфики развития территории и экономического состояния региона. Обосновывается тезис о том, что в настоящее время молодежные НКО Ставропольского края малочисленны, их вклад в инновационное развитие региона в настоящее время оценивается как незначительный.
Ключевые слова: некоммерческие организации, молодежь, инновационное развитие, регион, Ставропольский край.
Energy Performance Assessment Framework for Residential Buildings in Saudi Arabia
Creators: name: AlHashmi, Mohammad
name: Chhipi-Shrestha, Gyan
name: Ruparathna, Rajeev
name: Nahiduzzaman, Kh  Md
name: Hewage, Kasun
name: Sadiq, Rehan
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2021

description: The residential sector consumes about 50% of the electricity produced from fossil fuels in Saudi Arabia. The residential energy demand is increasing. Moreover, a simple building energy performance assessment framework is not available for hot arid developing countries. This research proposes an energy performance assessment framework for residential buildings in hot and arid regions, which focuses on three performance criteria: operational energy, GHG emissions, and cost. The proposed framework has been applied to three types of residential buildings, i.e., detached, attached, and low-rise apartments, in five geographical regions of Saudi Arabia. Design Builder® was used to simulate the energy demand in buildings over a whole year. Four types of efficiency improvement interventions, including double-glazed windowpanes, triple-glazed windowpanes, LED lighting, and split air conditioners, were introduced in 12 combinations. Overall, 180 simulations were performed which are based on 12 intervention combinations, three building types, and five regions. Three performance criteria were evaluated for each simulation and then aggregated using a multi-criteria decision analysis method to identify the best intervention strategy for a given building type and a geographical region in Saudi Arabia. Each building type with interventions consumes higher energy in the western, central, and eastern regions and consumes a lesser amount of energy in the southern and northern regions. The proposed framework is helpful for long-term planning of the residential sector.