cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Development of chemical tools to study protein palmitoylation and palmitoyl acyltransferases
Creators: name: Masumoto, Naoko
Publisher: name: Imperial College London
Year: 2015

description: Protein palmitoylation is an attachment of palmitate which is one of the most common post-translational modifications (PTMs) of proteins. It is important in various cellular events, and dysregulation has been observed in many diseases including cancer and neurological/neuropsychiatric disorders. There is increased interest in the development of novel therapeutic agents targeting palmitoyl acyltransferases (PATs); however, progress in understanding palmitoylated proteins/PATs has been slow due to the nature of modification and the lack of reliable assays until the recent development of the bioorthogonal ligation technique. Within the rich array of palmitoylated proteins, the main focus of this thesis was on Hedgehog (Hh) proteins which are irreversibly palmitoylated unlike the majority of reversibly palmitoilated proteins. Hh proteins act as morphogens in embryonic development and play a crucial role in tissue homeostasis in adult organisms. Mutations in various Hh signal transduction effectors and aberrant Hh signalling results in developmental malformation and tumourigenesis in adults. Hh proteins are dual lipidated (N-terminal cysteine by palmitate and C terminal glycine by cholesterol) in order to produce mature, fully-functional Hh signalling ligands. Irreversible N-palmitoylation of Hh proteins is catalysed by a member of membrane bound O-acyltransferases (MBOATs) called Hedgehog acyltransferase (HHAT). Efforts have been made to find pharmacologic agents to control the Hh signalling pathway; however, inhibition of downstream Hh signal components has led to the emergence of drug resistance, thus there being an urgent need to circumvent such issues. RU-SKI candidate HHAT inhibitors have opened new avenues to control Hh signalling by inhibiting palmitoylation of Hh ligands, hence attenuating the activation of the Hh pathway. This thesis describes the utilisation of the bio-orthogonal ligation technique to profile palmitoylated proteins, particularly the most abundant Hh homologue, Sonic Hedgehog (Shh) protein, using a palmitate mimic, YnPalm, in cell-based assays. After profiling Shh palmitoylation in depth, detailed characterisation of RU-SKI inhibitors has been performed to understand the effect of Shh secretion and cell signal transduction upon HHAT inhibition. Known PAT inhibitors were derived from chemical reporters in order to elucidate the target proteins by chemical proteomics approach. In short, RU-SKI inhibitors are highly selective against HHAT in terms of profiling their effects in global palmitoylation; however, their toxic effects towards signal reporter cell lines have interrogated the accurate read out in cell signalling activity. From the PAT inhibitor characterisation work, it has been reiterated that there are no specific PAT inhibitors available to date.
Rosa eglanteria Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rosaceae
Rosa
Rosa eglanteria

description: Rosa eglanteria, spec. nov.
 2. Rosa aculeata, foliis odoratis subtus rubiginosis. Hall. helv. 350. Dalib. paris. 145.
 Rosa sylvestris, foliis odoratis. Bauh. pin. 483.
 Rosa eglanteria. Tabern. ic. 1087.
 Habitat in Helvetia , Anglia . ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 491, DOI: 10.5281/zenodo.3931989
HST Observations of Giant Arcs: High Resolution Imaging Of Distant Field Galaxies.
Creators: name: Smail, Ian
name: Dressler, Alan
name: Kneib, Jean-Paul
name: Ellis, Richard S.
name: Couch, Warrick J.
name: Sharples, Ray M.
name: Oemler, Augustus
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present HST imaging of eight spectroscopically-confirmed giant arcs, pairs and arclets. These objects have all been extensively studied from the ground and we demonstrate the unique advantages of HST imaging in the study of such features by a critical comparison of our data with the previous observations. In particular we present new estimates of the core radii of two clusters (Cl0024+16, A370) determined from lensed features which are identifiable in our HST images. Although our HST observations include both pre- and post-refurbishment images, the depth of the exposures guarantees that the majority of the arcs are detected with diffraction-limited resolution. A number of the objects in our sample are multiply-imaged and we illustrate the ease of identification of such features when working at high resolution. We discuss the morphological and scale information on these distant field galaxies in the light of HST studies of lower redshift samples. We conclude that the dominant population of star-forming galaxies at z=1 is a factor of 1.5-2 times smaller than the similar group in the local field. This implies either a considerable evolution in the sizes of star-forming galaxies within the last $\sim$10 Gyrs or a shift in the relative space densities of massive and dwarf star-forming systems over the same timescale.
description: 9 pages (no figures), uuencoded, compressed Postscript. Postscript text, tables and figures (803 Kb) available via anonymous ftp in at ftp://ociw.edu//pub/irs/pub/hstarcs.tar.Z
title: MUSIC THERAPY: THE THIRD WAY
title: Μουσικοθεραπεία: ο τρίτος δρόμος
Creators: name: Psaltopoulou, Theodora
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΜΟΥΣΙΚΟΘΕΡΑΠΕΑ
ΕΙΔΙΚΗ ΑΓΩΓΗ
ΧΡΟΝΙΟΙ ΠΑΣΧΟΝΤΕΣ
ΜΕΛΕΤΗ ΠΕΡΠΤΩΣΗΣ
Music Therapy
Special Needs
Case Study

description: Μέρος του 2ου, 3ου, 4ου, 5ου και 7ου κεφαλαίου είναι από την προσωπική μου διατριβή, από εισηγήσεις σε συνέδρια, δημοσιεύσεις σε επιστημονικά περιοδικά και εκδηλώσεις παραστάσεων κοινωνικής μουσικοθεραπείας, τα οποία αναφέρονται στις βιβλιογραφικές αναφορές.
Μέρος του 6ου κεφαλαίου είναι από προφορικές εισηγήσεις σε επιστημονικά συνέδρια.
Determining $Ω$ from cluster correlation function
Creators: name: Kashlinsky, A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It is shown how data on the cluster correlation function can be used in order to reconstruct the density of the pregalactic density field on the cluster mass scale. The method is applied to the data on the cluster correlation amplitude -- richness dependence. The spectrum of the recovered density field has the same shape as the density field derived from data on the galaxy correlation function which is measured as function of linear scales. Matching the two amplitudes relates the mass to the comoving scale it contains and thereby leads to a direct determination of $Ω$. The resultant density parameter turns out to be $Ω$=0.25.
description: to appear in Physics Reports, "Dark Matter 98", vol.306
title: ADCO, Cartulaire de Cîteaux dit Cartularium Vetus (milieu XIIIe siècle) et Notices du XIIe siècle, Cart. 169 (11 H 63), f. 0056r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux dit Cartularium Vetus (milieu XIIIe siècle) et Notices du XIIe siècle, Archives départementales de la Côte-d'Or, Cart. 169 (11 H 63), f. 0056r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux dit Cartularium Vetus (milieu XIIIe siècle) et Notices du XIIe siècle, Archives départementales de la Côte-d'Or, Cart. 169 (11 H 63), f. 0056r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Rosa rubiginosa Linnaeus 1771
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rosaceae
Rosa
Rosa rubiginosa

description: Rosa eglanteria Linnaeus, Species Plantarum 1: 491. 1753, nom. utique rej.
"Habitat in Helvetia, anglia [sic]." RCN: 3731.
Lectotype (Heath in Calyx 1: 153. 1992): [icon] " Rosa Eglenteria " in Tabernaemontanus, Eicones Pl.: 1087. 1590.
Current name: Rosa rubiginosa L. (Rosaceae).
Note: See an extremely detailed discussion by Reichert (in Gleditschia 24: 18-22. 1997), who also illustrates the type (p. 21). The name has subsequently been formally rejected.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 799, DOI: 10.5281/zenodo.291971
Biomimetic synthesis of resorcylates natural products and analogues
Creators: name: Barrett, Tim
Publisher: name: Imperial College London
Year: 2015

description: The resorcylate unit (2, 4-dihydroxybenzoic acid) is found in numerous biologically active natural products. This thesis outlines the application of a novel biomimetic synthesis strategy to the syntheses of resorcylate natural products and analogues. A synthetic pathway to the meroterpenoid antibiotic Hongoquercin B has been successfully developed in nine steps from trans, trans-farnesyl acetate using a double biomimetic strategy. A regioselective decarboxylative farnesyl migration and cycloaromatisation gave the resorcylate, which undergoes a lewis acid mediated diastereoselective cationic epoxy-diene cascade cyclisation to give the tetracyclic core. The single epoxy-farnesyl stereocentre was used to control the remaining 4 stereocentres of the tetracyclic core. This cascade tetracyclisation sequence simplifies the synthesis of terpenoid resorcylate natural products. Efficient syntheses of a range C-5 substituted resorcylates and resorcinamides from functionalised keto-dioxinones are also described.Functionalized keto-dioxinones, generated via enolate acylation or alkylation reactions, were subsequently C-formylated and cyclised to the corresponding arenes. Further manipulations gave a wide range of structures of potential pharmaceutical interest including C-5-substituted, C-4,5-cyclo-fused and C-5,6-cyclo-fused resorcylates, as well as resorcinamides. The syntheses are noted for brevity with a maximum of 5 synthetic steps and without the need for protection of phenol groups.(b)
Genetic dissection of hypothalamic sleep circuitry
Creators: name: Zhang, Zhe
Publisher: name: Imperial College London
Year: 2015

description: Do sedative drugs engage the natural sleep circuitry to produce their effects? In particular, the sedated state induced by hypnotic drugs acting at adrenergic type 2A receptors (adra2a) is difficult to distinguish from natural deep non-REM sleep, but most researchers believe these are distinct vigilance states. Here I use pharmacogenetics to demonstrate that 2 adrenergic receptor agonist (dexmedetomidine)-induced sedation, and the recovery sleep induced following sleep deprivation, do in fact share a common neuronal circuitry such that recovery sleep and sedation appear to be the same. To do this I used the TetTaging method. I expressed c-fos-promoter inducible hM3Dq receptor genes selectively in the preoptic area (PO). I then gave mice sleep deprivation and allowed them recovery sleep or sedative doses of dexmedetomidine. Only neurons previously active during rebound sleep following sleep-deprivation or those disinhibited by dexmedetomidine expressed hM3Dq receptors. Remarkably, NREM sleep with the accompanying drop in body temperature could be induced by selectively re-activating these “neural engrams” using systemic CNO a few days later. After sleep deprivation and recovery sleep, selective reactivation of neuronal ensembles in either MnPO or the LPO areas was sufficient to induce powerful NREM sleep; after dexmedetomidine-induced sedation, only selective reactivation of the LPO area could induce NREM sleep. Selective ablation of the vesicular GABA transporter gene in the LPO neurons hindered dexmedetomidine’s ability to induce sedation, suggesting that the neurons disinhibited by dexmedetomidine were GABAergic.
Reminiscences of Victor Rabinowitz, 1990
Publisher: name: Columbia University
Year: 2021
Subjects: Lawyers
Practice of law
Labor unions and communism
Internal security--United States
Constitutional law
Civil rights--United States
International law
Labor laws and legislation

description: Family background, education; early legal work for trade unions, New York, N.Y.; American Labor Party, 1936; Boudin, Cohn and Glickstein, 1938-42; association with Communist-influenced unions, national and state labor boards; foundation of own firm, 1942; effects of Taft-Hartley Act, internal security investigations, American Communications Association vs Douds, Steve Nelson case; discussion of Judith Coplon and Rosenberg cases; Teachers Union, New York, N.Y., and Board of Education; Jimmy Hoffa; representing Castro government from 1960
Passive sampling calibration for persistent and mobile substances
Creators: name: Knight, Emma R
Publisher: name: Zenodo
Year: 2024
Subjects: subject: PFAS
subject: POPs
subject: Benzotriazole
subject: Monitoring
subject: Environmental sciences

description: Presentation at the Socitey of Toxicology and Chemistry (SETAC) Europe 34th Annual Meeting, Seville, Spain, 5-9th May 2024 in the session '3.19 Passive sampling: Analysis, Transport and Monitoring of Persistent, Mobile and Toxic Substances in the Environment'.

Contains preliminary data that may be shared in the future.
A FIRST DETERMINATION OF THE SURFACE DENSITY OF GALAXY CLUSTERS AT VERY LOW X--RAY FLUXES
Creators: name: Rosati, P.
name: Della Ceca, R.
name: Burg, R.
name: Norman, C.
name: Giacconi, R.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the first results of a serendipitous search for clusters of galaxies in deep ROSAT-PSPC pointed observations at high galactic latitude. The survey is being carried out using a Wavelet based Detection Algorithm which is not biased against extended, low surface brightness sources. A new flux--diameter limited sample of 10 cluster candidates has been created from $\rm\sim 3 \, deg^2$ surveyed area. Preliminary CCD observations have revealed that a large fraction of these candidates correspond to a visible enhancement in the galaxy surface density, and several others have been identified from other surveys. We believe these sources to be either low--moderate redshift groups or intermediate to high redshift clusters. We show X-ray and optical images of some of the clusters identified to date. We present, for the first time, the derived number density of the galaxy clusters to a flux limit of $\rm 1\cdot 10^{-14} erg cm^{-2} s^{-1}$ (0.5--2.0 keV). This extends the $\log N$--$\log S$ of previous cluster surveys by more than one decade in flux. Results are compared to theoretical predictions for cluster number counts.
description: uuencoded compressed Postscript, 7 pages including 4 figures. Accepted for publication in Ap. J. Letters.
Synthesis, characterization, HSA interaction and antibacterial activity of a new water-soluble Pt(II) complex containing the drug cephalexin
Creators: name: Shahabadi, Nahid
name: Shokoufeh Hashempour
name: Avat (Arman) Taherpour
name: Mohsenzadeh, Fariba
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: A new water-soluble platinum(II) complex, [Pt(CEX)Cl(DMSO)]Cl (CEX is cephalexin), was synthesized and characterized by physicochemical, spectroscopic and computational methods. Multispectroscopic techniques were used to investigate the interaction of Pt(II) complex with human serum albumin (HSA) under the physiological conditions. The results of fluorescence titration indicated that the binding of the Pt(II) complex to HSA induced fluorescence quenching through static quenching mechanism with binding constant of 1.24 × 104 M−1 at 298 K. The thermodynamic parameters at different temperatures indicated that van der Waals forces, hydrogen bonds and electrostatic forces play major roles in the stability of Pt(II) complex-HSA association. The displacement experiments using the site probes warfarin and ibuprofen substantiated that Pt(II) complex could bind to both site I and II of HSA. Furthermore, UV-vis and fluorescence spectra were used to investigate the conformational changes of HSA molecule with the addition of Pt(II) complex. The binding constant of Pt(II) complex is more than two orders of magnitude higher than the corresponding value of cephalexin. These results indicate that the binding affinity of Pt(II) complex is stronger than the free drug. In addition, the antibacterial study showed that the MIC of platinum complex of cephalexin for variety of organisms was lower than free cephalexin.
Zeta functions of nondegenerate hypersurfaces in toric varieties via controlled reduction in $p$-adic cohomology
Creators: name: Costa, Edgar
name: Harvey, David
name: Kedlaya, Kiran S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Number Theory (math.NT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 11G25, 14G10, 11M38, 11Y16, 14C25

description: We give an interim report on some improvements and generalizations of the Abbott-Kedlaya-Roe method to compute the zeta function of a nondegenerate ample hypersurface in a projectively normal toric variety over $\mathbb{F}_p$ in linear time in $p$. These are illustrated with a number of examples including K3 surfaces, Calabi-Yau threefolds, and a cubic fourfold. The latter example is a non-special cubic fourfold appearing in the Ranestad-Voisin coplanar divisor on moduli space; this verifies that the coplanar divisor is not a Noether-Lefschetz divisor in the sense of Hassett.
description: 17 pages, 3 figures; v3 updated discussion regarding cubic fourfolds
Rosa gallica Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rosaceae
Rosa
Rosa gallica

description: Rosa gallica, spec. nov.
 8. Rosa foliis carinatis subtus scabris. Dalib. paris. 145. †
 Habitat in Gallia . ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 492, DOI: 10.5281/zenodo.3931989
Studies of recombination in organic and hybrid solar cells using electroluminescence
Creators: name: Yao, Jizhong
Publisher: name: Imperial College London
Year: 2016

description: The performance of solution processed solar cells such as organic bulk heterojunction (OPV) devices is limited by strong recombination. However, the mechanisms are still unclear. In this thesis, I develop a toolbox using steady-state spectroscopy measurements to explore the recombination mechanisms in a range of solution-processed solar cells. In the first results chapter, I use the reciprocity relation between light absorption and light emission to explore theoretical and practical performance limits for solar cells based on organic semiconductors and perovskites and compare the results with data for state-of-the-art photovoltaic cells made from GaAs, c-Si, and CIGS. In OPV systems, I show that the energetic losses due to the mismatch of the bandgap have been significantly reduced through optimisation of the donor polymer, but the non-radiative recombination losses remain the same and become the major barrier to higher performance. In the next two chapters, I use light intensity dependence of open-circuit voltage measurement (suns-VOC) and electroluminescence – injection current measurement (EL-J) to disentangle recombination mechanisms in OPV and perovskite cells, respectively. First, I identify the present of Shockley-Read-Hall recombination and surface recombination in OPV devices. I intentionally control the sample geometry to modulate the amount of surface recombination and demonstrate that surface recombination can significantly affect the device performance. In the following chapter, I analyse time dependent suns-VOC and EL-J measurements on perovskite cells with different architectures and pre-conditioning regimes used. I identify the changes in recombination mechanisms with delay time and pre-conditions. The effects of ion migration are used to interpret the results. In the final chapter, I apply luminescence spectroscopy techniques to investigate the degree of fullerene crystallinity in polymer:fullerene blends. Charge-transfer state emission is used to probe the onset of the crystallisation of fullerenes in an amorphous polymer. I relate the CT peak shift directly to the change in microstructure of a blend film.
Rosa gallica Linnaeus 1762
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rosaceae
Rosa
Rosa gallica

description: Rosa gallica Linnaeus, Species Plantarum 1: 492. 1753.
"Habitat in Gallia." RCN: 3742.
Lectotype (Jafri in Jafri & El-Gadi, Fl. Libya 31: 26. 1977): Herb. Linn. No. 652.26 (LINN).
Current name: Rosa gallica L. (Rosaceae).
Note: Jafri’s type choice is clear, though there has been some subsequent discussion as to its appropriateness (see Heath in Calyx 4: 60-61. 1994; Reichert in Gleditschia 24: 13, 15-16. 1997). Ghora & Panigrahi (Fam. Rosaceae India 2: 316-322. 1995) illustrate the type (as pl. 60A).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 799, DOI: 10.5281/zenodo.291971
Reconstruction Analysis of Galaxy Redshift Surveys: A Hybrid Reconstruction Method
Creators: name: Narayanan, Vijay K.
name: Weinberg, David H.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In reconstruction analysis of galaxy redshift surveys, one works backwards from the observed galaxy distribution to the primordial density field in the same region, then evolves the primordial fluctuations forward in time with an N-body code. This incorporates assumptions about the cosmological parameters, the properties of primordial fluctuations, and the biasing relation between galaxies and mass. These can be tested by comparing the reconstruction to the observed galaxy distribution, and to peculiar velocity data. This paper presents a hybrid reconstruction method that combines the `Gaussianization'' technique of Weinberg(1992) with the dynamical schemes of Nusser & Dekel(1992) and Gramann(1993). We test the method on N-body simulations and on N-body mock catalogs that mimic the depth and geometry of the Point Source Catalog Redshift Survey and the Optical Redshift Survey. This method is more accurate than Gaussianization or dynamical reconstruction alone. Matching the observed morphology of clustering can limit the bias factor b, independent of Omega. Matching the cluster velocity dispersions and z-space distortions of the correlation function xi(s,mu) constrains the parameter beta=Omega^{0.6}/b. Relative to linear or quasi-linear approximations, a fully non-linear reconstruction makes more accurate predictions of xi(s,mu) for a given beta, thus reducing the systematic biases of beta measurements and offering further scope for breaking the degeneracy between Omega and b. It also circumvents the cosmic variance noise that limits conventional analyses of xi(s,mu). It can also improve the determination of Omega and b from joint analyses of redshift & peculiar velocity surveys as it predicts the fully non-linear peculiar velocity distribution at each point in z-space.
description: 72 pages including 33 figures, submitted to ApJ
Fluidization of epithelial sheets by active cell rearrangements
Creators: name: Krajnc, Matej
name: Dasgupta, Sabyasachi
name: Ziherl, Primož
name: Prost, Jacques
Publisher: name: arXiv
Year: 2018
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We theoretically explore fluidization of epithelial tissues by active T1 neighbor exchanges. We show that the geometry of cell-cell junctions encodes important information about the local features of the energy landscape, which we support by an elastic theory of T1 transformations. Using a 3D vertex model, we show that the degree of active noise driving forced cell rearrangements governs the stress-relaxation time-scale of the tissue. We study tissue response to in-plane shear at different time scales. At short time, the tissue behaves as a solid, whereas its long-time fluid behavior can be associated with an effective viscosity which scales with the rate of active T1 transformations. Furthermore, we develop a coarse-grained theory, where we treat the tissue as an active fluid and confirm the results of the vertex model. The impact of cell rearrangements on tissue shape is illustrated by studying axial compression of an epithelial tube.
Spectroscopic, DFT, biological, DNA-binding and antioxidant studies of some metal chelates with a novel thiazole-derived Schiff base
Creators: name: Mohamed, Rania G.
name: Abdelmoneim A. Makhlouf
name: Sherin A. Mosad
name: Aziz, Ayman A. Abdel
name: El-Medani, Samir M.
name: Ramadan, Ramadan M.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Thermal reactions of Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Ru(III) metal ions with a novel Schiff base ligand (HL) derived from the condensation of 2-aminothiazole and 2-hydroxy-1-naphthaldehyde resulted in the formation of a series of metal complexes, [Co(L)2(H2O)2]·2H2O (1), [Ni(L)(CH3COO)(H2O)2] (2), [Cu(L)2(H2O)2] (3), [Zn(L)2] (4), [Cd(L)(CH3COO)]·2H2O (5) and [Ru(L)2(H2O)2]Cl (6). The ligand and its complexes were characterized by means of elemental and thermal analyses, molar conductance, magnetic moment measurements along with the different spectroscopic techniques. The structure of the ligand was determined by X-ray crystal structure analysis and revealed that it crystallized in the orthorhombic space group P21cn with a Z value of 4. Theoretical calculations based on accurate DFT approximations were used to verify the structures of ligand and complexes. The relative reactivities were estimated using chemical descriptors analysis. The biological activities of the compounds were examined. The antioxidant activity against DPPH radical was evaluated in vitro by using spectrophotometric methods; the experiments showed potent antioxidant activity. Also, the interaction of the reported compounds with calf-thymus DNA (CT-DNA) by different techniques revealed that the complexes could bind to CT-DNA by intercalative mode.
Quantum walk on a toral phase space
Creators: name: Omanakuttan, Sivaprasad
name: Lakshminarayan, Arul
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A quantum walk on a toral phase space involving translations in position and its conjugate momentum is studied in the simple context of a coined walker in discrete time. The resultant walk, with a family of coins parametrized by an angle is such that its spectrum is exactly solvable with eigenangles for odd parity lattices being equally spaced, a feature that is remarkably independent of the coin. The eigenvectors are naturally specified in terms the $q-$Pochhammer symbol, but can also be written in terms of elementary functions, and their entanglement can be analytically found. While the phase space walker shares many features in common with the well-studied case of a coined walker in discrete time and space, such as ballistic growth of the walker position, it also presents novel features such as exact periodicity, and formation of cat-states in phase-space. Participation ratio (PR) a measure of delocalization in walker space is studied in the context of both kinds of quantum walks; while the classical PR increases as $\sqrt{t}$ there is a time interval during which the quantum walks display a power-law growth $\sim t^{0.825}$. Studying the evolution of coherent states in phase space under the walk enables us to identify an Ehrenfest time after which the coin-walker entanglement saturates.
Entangled end states with fractionalized spin projection in a time-reversal-invariant topological superconducting wire
Creators: name: Aligia, Armando
name: Arrachea, Liliana
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the ground state and low-energy subgap excitations of a finite wire of a time-reversal-invariant topological superconductor (TRITOPS) with spin-orbit coupling. We solve the problem analytically for a long chain of a specific one-dimensional lattice model in the electron-hole symmetric configuration and numerically for other cases of the same model. We present results for the spin density of excitations in long chains with an odd number of particles. The total spin projection along the axis of the spin-orbit coupling $S_z= \pm 1/2$ is distributed with fractions $\pm 1/4$ localized at both ends, and shows even-odd alternation along the sites of the chain. We calculate the localization length of these excitations and find that it can be well approximated by a simple analytical expression. We show that the energy $E$ of the lowest subgap excitations of the finite chain defines tunneling and entanglement between end states.We discuss the effect of a Zeeman coupling $Δ_Z$ on one of the ends of the chain only. For $Δ_Z
description: 14 pages, 8 Figures
Organometallic-mediated radical polymerization using well-defined Schiff base cobalt(II) complexes
Creators: name: Silva, Yan F.
name: Riga, Beatriz A.
name: Deflon, Victor M.
name: Jhonathan R. Souza
name: Silva, Leonardo H. F.
name: Machado, Antonio E. H.
name: Maia, Pedro Ivo S.
name: Carvalho-Jr Valdemiro, P.
name: Goi, Beatriz E.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: A series of new cobalt(II) complexes of Schiff base derived from salicylaldehyde and different cycloalkylamines (cycloalkyl = cyclopentyl-1a, cyclohexyl-1b, and cycloheptyl-1c) was synthesized: [Co(CyPen-Salicyl)2] (2a), [Co(CyHex-Salicyl)2] (2b), and [Co(CyHep-Salicyl)2] (2c). The bis(phenoxyiminato)Co(II) complexes (2a-2c) have been fully characterized by FTIR and UV–vis spectroscopy, elemental analysis, cyclic voltammetry, computational methods, and two of the complexes were further studied by single crystal X-ray crystallography. The X-ray structure analysis of 2a-b shows that the geometry around the metal atom is a distorted tetrahedron, confirming the spectroscopic data. Electrochemical studies suggest that the redox potential of 2a-2c are sensitive to the substituent group, decreasing in order cyclopentyl > cyclohexyl > cycloheptyl. Complexes 2a-2c were used as controlling agents for the polymerization of vinyl acetate (VAc) initiated by AIBN, according to a cobalt-mediated radical polymerization (CMRP) mechanism. The VAc polymerization mediated by 2a-2c suggests that the level of control can be slightly tuned by the substitution of the cycloalkyl group on the Schiff base ligand. Complex 2b showed the smaller discrepancy between observed and calculated molecular weight, and narrower molecular weight distribution.
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0530
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0530, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0530, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Condition for the emergence of a bulk Fermi arc in disordered Dirac-fermion systems
Creators: name: Zhao, Peng-Lu
name: Wang, An-Min
name: Liu, Guo-Zhu
Publisher: name: arXiv
Year: 2018
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a renormalization group analysis of the disorder effects on the low-energy behaviors of twodimensional tilted Dirac-fermion systems, in which the fermions have two distinct orbitals unrelated by any symmetry. Four types of disordered potential, two interorbital and two intraorbital, are considered. If there is only one type of interorbital disorder, the fermion-disorder scattering induces logarithmic or power-law corrections to the fermion density of states and specific heat. In contrast, the intraorbital disorder can turn the system into a strongly disordered phase. In this disordered phase, calculations based on self-consistent Born approximation reveal that the Dirac point is destroyed and replaced by a bulk Fermi arc. We also study the interplay of four types of disorder, and find that the Dirac point can either remain intact or give place to a Fermi arc. We obtain the condition for the emergence of a Fermi arc in this case. Our results indicate that disorders can result in rich low-energy properties of tilted Dirac fermions.
description: 9+9 pages,7 figures,published version
The Dwarf Galaxy NGC 1705 -- A Highly Composite Stellar Population
Creators: name: Quillen, A. C.
name: Ramírez, Solange V.
name: Frogel, Jay A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present visible and near-infrared images of the amorphous dwarf galaxy NGC 1705 in the $B$, $V$, $R$, $J$, $H$, and $K$ bands. Optical and near infrared colors in the galaxy are consistent with a composite population with colors similar to those of the bluest Sc nuclei. The contribution of young stars to the disk population of the galaxy decreases outwards from the center. In the near infrared images we detect three unresolved point sources, two of which have colors and luminosities comparable to intermediate age LMC clusters.
description: uuencoded compressed tarred postscript including figures. Accepted for publication in AJ.
Additional file 3 of Characterization of tea (Camellia sinensis L.) flower extract and insights into its antifungal susceptibilities of Aspergillus flavus
Creators: name: Chen, Fangfang
name: Chen, Yu-Pei
name: Wu, Hongtan
name: Li, Ya
name: Zhang, Shudi
name: Ke, Jincheng
name: Yao, Jeng-Yuan
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Supplementary Material 3
The Star Formation Rate of the Local Universe from the KPNO International Spectroscopic Survey
Creators: name: Gronwall, Caryl
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The KPNO International Spectroscopic Survey (KISS) is a wide-field survey for extragalactic emission-line objects being carried out with the Burrell Schmidt at Kitt Peak. The critical difference between this survey and classical objective-prism surveys for active galaxies is the use of a CCD detector which allows us to probe to much fainter magnitudes than previous photographic surveys. We have discovered 1126 emission-line galaxy (ELG) candidates in our H-alpha selected survey area of ~68 square degrees. We have used these ELGs to derive the local H-alpha luminosity density and the star formation rate density of the local universe and find values somewhat higher than those reported by Gallego et al.
description: 4 pages, 2 figures, style files included; to appear in "Dwarf Galaxies and Cosmology", eds. Thuan et al., Editions Frontieres
A Computational Investigation of Local Interactions Within Ionic Liquids and Ionic Liquid Analogues
Creators: name: Ashworth, Claire
Publisher: name: Imperial College London
Year: 2015

description: The potential applications of ionic liquids and related analogues are diverse. However, for large-­scale industrial applications low cost ionic liquids are required. Moreover, for the full potential of ionic liquids to be realised, a fundamental link between molecular level interactions, structuring and the bulk phase properties must be established. Deep eutectic solvents (DESs) and protic ionic liquids have been identified as candidates for the potential application of chalcopyrite leaching. The choline chloride – urea DES and 1-­ butylimidazolium hydrogensulphate protic ionic liquid were selected as systems of primary interest. Local structuring within the selected systems has been investigated, with an emphasis on the hydrogen bonding interactions. The choline chloride – urea mixture is a prototypical example of a DES. Using DFT, the pairwise interactions between the constituent components, and within clusters composed of n.urea.choline-­chloride (n = 1-­3), have been evaluated. Many different types of hydrogen bond have been identified, exhibiting flexibility in both strength and number. The formation of the commonly proposed [2urea⋅Cl]– complexed anion has been scrutinised and found to be energetically competitive with other interactions. Moreover, contrary to existing proposals, the negative charge is found to remain localised on chloride. The cation-­anion and anion-­anion interactions within [C4Him][HSO4] and related systems have been compared and contrasted;; ion pairs were evaluated using DFT and the bulk systems modelled using classical MD. Local structuring within [C4Him][HSO4] exhibits features of both the aprotic analogue and alkylammonium protic ionic liquids. [HSO4]–⋅⋅⋅[HSO4]– interactions have been considered and found to be a notable feature of the [HSO4]– ionic liquids studied. It is anticipated that the formation of [HSO4]– aggregates influences the properties of the bulk systems. A QM/MM method for the study of ionic liquids is introduced. Preliminary analysis suggests that this is a viable approach for the investigation of local structuring within ionic liquids.
Multi-Band Images of the Barred Galaxy NGC 1097
Creators: name: Quillen, A. C.
name: Frogel, Jay. A.
name: Kuchinski, L. E.
name: Terndrup, D. M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present $B,V,R,J,H,K$ broad--band images of the barred galaxy NGC 1097. The optical and infrared colors maps trace the location of the major dust features. The dust lanes are relatively free of star formation and have low opacity. The depth of the dust lanes decreases as a function of wavelength so that they are deepest at $B$ and shallower at $H$ and $K$ where they are difficult to detect. We find that the dust lane on the north-west side of the galaxy has colors consistent with those of a dust screen with opacity derived from the galactic extinction law. Thus, it must be located on the near side of the galaxy. The colors in the dust lane on the south-east side of the galaxy, on the other hand, suggest that there are stars both in front of and behind the dust, consistent with this dust lane being located on the far side of the galaxy. Near the inner spiral ring (at $\sim 17'' = 1.4$kpc from the nucleus), the dust lane becomes double peaked with peak to valley extinction ratio similar to that observed in radio continuum by Ondrechen and van der Hulst (1983). This suggests that if the cold diffuse component of the interstellar medium (traced by the dust) moves with the cosmic ray electron component then the magnetic field pressure is not a significant force in the shocks. Alternatively if the two phases do not move together a more detailed comparison may show differences in the shock shapes. From the $K$ images, we estimate that the total stellar mass of the star forming spiral ring at a radius of $\sim$ 1kpc from the nucleus is of the same order as the molecular gas mass in the ring. The infrared images show a short bar inside the inner spiral ring. In the principal plane of the galaxy, the short bar is not perpendicular to the prominent outer bar. This suggests that there are torques between the inner bar and the spiral
description: uuencoded compressed postscript of paper. Tarred compressed paper and figures are available by anonymous ftp at ftp://payne.mps.ohio-state.edu/pub/quillen/n1097/
The X-ray Expansion of the Supernova Remnant Cassiopeia A
Creators: name: Koralesky, Barron
name: Rudnick, L.
name: Gotthelf, E. V.
name: Keohane, J. W.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the first X-ray expansion measurement of the SNR Cas A. We compared new ROSAT to archived Einstein HRI images with a separation of 17 years. The remnant is seen to be expanding, on average, at a rate of 0.20 %/yr, which is twice as fast as the expansion of the bright radio ring and two-thirds as fast as the ensemble of optical Fast Moving Knots. This argues that we are observing different hydrodynamical structures in each band, although all of these components are located on the same patchy ring. In addition, significant variations in expansion rate as a function of azimuth around the bright X-ray ring are found. These findings are discussed in the context of two classes of models, involving either an ambient medium with a uniform or monotonically decreasing density away from the center, or a pre-existing circumstellar shell.
description: 9 pages, 2 figures, Submitted to ApJL
Investigating the role of two activating receptors, NKG2D and NKp46, in natural killer cell education and in the development of hepatocellular carcinoma linked to chronic inflammation
Creators: name: Sheppard, Sam
Publisher: name: Imperial College London
Year: 2013

description: Natural killer (NK) cells are innate lymphocytes capable of identifying infected and tumourigenic cells and eliciting a cytokine and/or cytotoxic response. NK cells contain multiple activating and inhibitory receptors that bind to ligands expressed on other cells, and responses to abnormal cells are triggered by an imbalance of NK receptor signalling in favour of activation. The NK population is phenotypically and functionally heterogeneous, allowing recognition and responses to stimuli in a broad array of diseases. Diversity within the NK cell repertoire is achieved through the processes of education and maturation, which determine the specific combination of receptors expressed on the cell surface of each NK cell and ensure self-tolerance. Inhibitory receptors play a well-established role in NK cell education, but the role of activating receptors in this process remains unclear. NKG2D and NKp46 are considered to be major NK cell activating receptors that are required for efficient clearance of neoplastic and virally infected cells. However, it is not established whether these receptors also have roles in NK cell education. The aim of the present investigation was to address this question by using a novel mouse model lacking expression of both receptors, which was generated in our laboratory by crossing mice heterozygous for the individual mutations on a C57BL/6 background. The single-knockout littermates were also used. The results indicate that NKG2D and NKp46 are not essential to NK cell development, which proceeds normally in the double-knockout (DKO) mice. With regard to NK cell education, NKG2D, but not NKp46, has a mild cell intrinsic effect on the composition of the NK cell repertoire. NKG2D also has a modest impact on NK cell maturation at the steady state. We found maturation was impaired in inflammatory contexts, suggesting that the tissue environment influences this phenotype. In parallel, the relevance of NKG2D in tumour development was investigated in a physiologically relevant carcinogen-induced model of hepatocellular carcinoma driven by inflammation. A significantly increased tumour burden was found in the presence of NKG2D. This correlated with increased infiltration of CD8+ T cells. The mechanism by which NKG2D acts to promote tumour development is not yet known, and the significance of the increase in CD8+ T cells remains to be elucidated. However, this finding strongly implies a pro-tumourigenic function for NKG2D, in addition to its known function as tumour suppressor.
Additional file 4 of Expanding the phenotypic spectrum of mutations in LRP2: a novel candidate gene of non-syndromic familial comitant strabismus
Creators: name: Wang, Yue
name: Chen, Xuejuan
name: Jiang, Tao
name: Gu, Yayun
name: Zhang, Xiaohan
name: Yuan, Wenwen
name: Zhao, Andi
name: Li, Rui
name: Wang, Zijin
name: Hu, Zhibin
name: Liu, Hu
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 4: Figure S2. Flow chart of variant analyses.