cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Continuous and first-order jamming transition in crossing pedestrian traffic flows
Creators: name: Hilhorst, H. J.
name: Cividini, J.
name: Appert-Rolland, C.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: After reviewing the main results obtained within a model for the intersection of two perpendicular flows of pedestrians, we present a new finding: the changeover of the jamming transition from continuous to first order when the size of the intersection area increases.
description: 14 pages, 9 figures
Q-LEACH: A New Routing Protocol for WSNs
Creators: name: Manzoor, B.
name: Javaid, N.
name: Rehman, O.
name: Akbar, M.
name: Nadeem, Q.
name: Iqbal, A.
name: Ishfaq, M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Wireless Sensor Networks (WSNs) with their dynamic applications gained a tremendous attention of researchers. Constant monitoring of critical situations attracted researchers to utilize WSNs at vast platforms. The main focus in WSNs is to enhance network life-time as much as one could, for efficient and optimal utilization of resources. Different approaches based upon clustering are proposed for optimum functionality. Network life-time is always related with energy of sensor nodes deployed at remote areas for constant and fault tolerant monitoring. In this work, we propose Quadrature-LEACH (Q-LEACH) for homogenous networks which enhances stability period, network life-time and throughput quiet significantly.
DEFINING THE GUN1-FTSH INTERACTIONS IN CHLOROPLAST BIOGENESIS IN ARABIDOPSIS THALIANA
Creators: name: PERACCHIO, CARLOTTA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: The GENOMES UNCOUPLED 1 (GUN1) gene has been reported to encode a chloroplast-localized pentatricopeptide-repeat protein (PPR), which acts to integrate multiple indicators of plastid developmental stage and altered plastid function, as part of chloroplast-to-nucleus retrograde communication. However, the molecular mechanisms underlying the GUN1-dependent signal integration have remained elusive, until the recent identification of a set of GUN1- interacting proteins, by co-immunoprecipitation and mass-spectrometric analyses, as well as protein?protein interaction assays. Within the list of GUN1 interactors the FtsH1, FtsH2, FtsH5 and FtsH8 subunits, that make up the thylakoid FTSH protease complex, were identified. The FtsH subunits are part of the ATP-dependent metalloprotease family and they play a fundamental role in the maintenance of the chloroplast protein homeostasis. In this thesis, I show that FtsH2 and FtsH5 subunits have a really important genetic interaction with GUN1 during the chloroplast biogenesis process in Arabidopsis cotyledons. In particular, I observed that GUN1 is important for the accumulation of the FtsH subunits in the thylakoid membranes, and for the import of several plastid precursor proteins that, in the absence of GUN1 protein, accumulate in the cytosol, with the consequent increase in total protein ubiquitination and cytosolic chaperone abundance. In the attempt to give a molecular explanation to the observation reported above, I was able to demonstrate that in condition of plastid protein homeostasis alteration, GUN1 controls the accumulation of Nuclear encoded RNA polymerase (NEP)-dependent transcripts and, indirectly, affects the chloroplast protein import apparatus, since a major component of the 1MDa TIC complex (Translocon at the Inner membrane of the Chloroplasts), i.e. Tic214, is encoded by the plastid genome. Such a defect in Tic214 accumulation appears to destabilize the entire plastid import machinery both in terms of protein amount and post-translation modification, as shown by the high ubiquitination levels of Toc34 subunit. Strikingly, such chloroplast alterations are sensed by nuclear transcription factors, as shown by the negative effect on the accumulation of HY5, a main transcription factor involved in retrograde signaling and chloroplast biogenesis. Overall, during this three year as Ph.D. student I believed to have discovered the primary function of GUN1 protein, shining a new light on the intricate network of chloroplast-nucleus communication.
GIUDIZIO CLINICO E SCALE PER LA STRATIFICAZIONE DEL RISCHIO DEI PAZIENTI CHE SI PRESENTANO IN PRONTO SOCCORSO PER SINCOPE: UNA META-ANALISI DI DATI INDIVIDUALI DI SINGOLI PAZIENTI
Creators: name: RUSCONI, ANNA MARIA
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: Background: There have been several attempts to derive emergency department (ED) syncope prediction tools (SPTs) to guide ED clinician decision-making. HoweverSPTs have not been largely adopted possibly because of their lack of sensitivity and specificity. We aimed to externally validate the existing SPTs and to compare them to clinical judgment (CJ), using an individual patient data meta-analysis approach. Methods: Electronic databases, bibliographiesand experts in the field were usedto find all prospective studies enrolling consecutive subjects presenting with syncope or near syncope to the ED. Only studies reporting subsequent adverse events and those with at least one SPT and CJ were considered. SPTs and CJ were individually applied to all patients in each dataset whenever possible. Serious outcomes and death were separately considered during ED stay and at 10 and 30 days after presenting syncope episode. Pooled sensitivities, specificities, likelihood ratios and diagnostic odds ratios, with 95% CIs were calculated. Results: Thirteen potentially relevant papers were retrieved (11 authors). Six authors agreed to share individual patient data. In total, 3681 patients were included. Three SPTs (OESIL, SFSR, EGSYS) were assessable with the available datasets. None of the evaluated SPTs performed better than CJ in identifying serious outcomes during ED stay, or at 10 and 30 days after syncope. Conclusions: ED STPs do not have better sensitivity, specificity, or prognostic yield than CJ at predicting short-term serious outcome in syncope. ED clinicians should not strictly apply a SPT in their clinical practice when assessing a patient with syncope in the ED.
title: Информационные технологии в производстве
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: В данном пособии представлены лабораторные работы, которые позволяют сформировать практические навыки эффективно применять встроенные средства электронной таблицы Microsoft Excel в процессе решения экономических задач. Каждое лабораторное занятие предусматривает перечень вопросов для самоконтроля, упражнений и индивидуальных заданий. Учебное пособие можно использовать для самостоятельного изучения электронной таблицы Microsoft Excel. Пособие может использоваться на лабораторных занятиях в процессе изучения дисциплины «Информационные технологии в менеджменте», «Информационные технологии в экономике», «Информационные системы в экономике» и других подобных дисциплин. Пособие предназначено для студентов, может быть полезно учителям средних образовательных учреждений при проведении элективных курсов данного направления. Учебное пособие соответствует требованиям ФГОС ВПО и ФГОС ВО.
title: Case-технологии и язык UML
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Предлагаемое пособие представляет курс теоретических вопросов и лабораторных занятий по основам языка UML. В пособии сквозным примером представлена последовательность проектирования информационной системы с помощью диаграмм UML. Целью учебного пособия является оказание помощи студентам в формировании профессиональных компетенции по овладению навыками в объектно-ориентированном проектировании. Данное учебное пособие можно использовать для самостоятельного изучения дисциплины «Case-технологии и язык UML», при подготовке к экзаменам и курсовой работе, а также в качестве методических рекомендаций для преподавателей. Учебное пособие предназначается для студентов, обучающихся по направлению 09.03.02 «Информационные системы и технологии» при изучении дисциплины «Case-технологии и язык UML», всех форм обучения.
Factors affecting SARS-COV-2 sequence conservation: SARSNTdb database
Creators: name: Orgera, John
Publisher: name: No Publisher Supplied
Year: 2022

description: SARSNTdb offers a curated, nucleotide-centric database for users of varying SARS-CoV-2 knowledge. Its user-friendly interface enables querying coding regions and coordinate intervals to find out the various functional and selective constraints that act upon the corresponding nucleotides and amino acids. Users can easily obtain information about viral genes and proteins, functional domains, repeats, secondary structure formation, intragenomic interactions, and mutation prevalence. Currently, many databases are focused on the phylogeny and amino acid substitutions, mainly in the spike protein. While providing mutation data, SARSNTdb takes a more nucleotide-focused approach as RNA does more than just code for proteins and many insights can be gleaned from its study. For example, RNA-targeted drug therapies for SARS-CoV-2 are currently being developed and it is essential to understand the features only visible at that level. This database enables the user to identify regions that are more prone to forming secondary structures that drugs can target. Finally, the database allows for comparing SARS-CoV-2 and SARS-CoV domains and sequences. SARSNTdb can serve the research community by being a curated repository for information that gives a jump start to analysing a mutation’s effect far beyond just determining synonymous/non-synonymous substitutions in protein sequences.
Doug Michel, 1943-2003
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021

description: DVD, "Doug Michels video clips, 6:30," includes footage from Truckstop Tour (1971), 100 Television Sets (1972), Time Capsule 1972-84 (1972, 2000), The Eternal Frame (1975), Cadillac Ranch, 10th Anniversary (1984) : 1 item
Truckstop Network
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Design

description: DVD, "Ant Farm Truckstop Network & Truckstop Tour Video: Sausalito Slide Show, Scottsdale Hilton, Ant Farm Documentation, Apollo 17, Media Van at Tulane, World's Longest Bridge, and Johnny Romeo at Yale" : 1 item
CHARACTERIZATION AND DISSECTION OF NATURAL GENETIC DIVERSITY FOR CULM TRAITS IN BARLEY (HORDEUM VULGARE L.)
Creators: name: BRETANI, GIANLUCA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: Barley (Hordeum vulgare L.) is one of the most important crops, with a worldwide grain production of more than 137,98 mln tons per year, 41% of which are produced in Europe. Barley production is threatened by climate change and the associated growing frequency of extreme weather events which results for example in increased lodging. Morphological culm features have been linked to lodging resistance and biomass production in rice and wheat, but the genetic architecture underlying culm traits has not been investigated in barley. Within the ClimBar project, the objective of my PhD research was to dissect natural genetic variation related to culm morphological traits in barley through association mapping on a collection of 198 diverse spring barley cultivars. As a critical region for lodging, we targeted the structure of 2nd basal internode from main stem: internode samples were collected in 2016 and 2017 from field-grown plants at dough stage (in Italy) and pre-harvest stage in four European locations (Spain, Italy, Finland and United Kingdom). Phenotypic data for culm diameter and culm wall thickness were obtained using a newly developed image analysis protocol based on ImageJ software. The number of vascular bundles from dough stage samples was also counted. Data for plant height, days to heading, lodging, and grain yield were also considered for further comparisons. Statistical analyses indicated the existence of significant genetic variation for the studied traits as supported by high heritability values. Combined analysis of variance indicated the existence of interaction between genotype and environment and this was mainly due to location by genotype, while the interaction due to year was less important, indicating the stability of the genotypes across years within the same location. Internode diameter and other culm related traits showed interesting correlations with other agronomical features, describing a complex system of interactions among the different plant organs and how they respond to the surrounding environment. Genome-wide marker data from a 50k iSelect Infinium SNP panel were used to run Genome-Wide Association Studies (GWAS) for plant height as validation trait, recovering markers in close proximity to well-known genes. GWAS revealed significant marker-trait associations for culm traits located within genomic regions harboring potential candidate genes mainly involved in the modification of cell wall composition and interacting with hormonal pathways. However, some associations were location-specific, due to the existence of GxE interactions for the traits under study. Together, our results provide the first insights into the genetic basis of culm morphology in barley and support the value of natural genetic diversity for the improvement of barley yield under climate change.
A Comparison Between Nonlinear Force-Free Field and Potential Field Models Using Full-Disk SDO/HMI Magnetogram
Creators: name: Tadesse, Tilaye
name: Wiegelmann, T.
name: Inhester, B.
name: Olson, K.
name: MacNeice, P. J.
name: Pevtsov, A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Measurements of magnetic fields and electric currents in the pre-eruptive corona are crucial to study solar eruptive phenomena, like flare and coronal mass ejections(CMEs). However, spectro-polarimetric measurements of certain photospheric lines permit a determination of the vector magnetic field at the photosphere. Thus, substantial collection of magnetograms relate to the photospheric surface field only. Numerical modeling is carried out by applying state-of-the-art nonlinear force-free field (NLFFF) reconstruction. Cartesian nonlinear force-free field (NLFFF) codes are not well suited for larger domains, since the spherical nature of the solar surface cannot be neglected when the field of view is large. One of the most significant results of Solar Dynamic Observatory (SDO) mission to date has been repeated observations of large, almost global scale events in which large scale connection between active regions may play fundamental role. Therefore, it appears prudent to implement a NLFFF procedure in spherical geometry for use when large scale boundary data are available, such as from the Helioseismic and Magnetic Imager (HMI) on board SDO. In this work, we model the coronal magnetic field above multiple active regions with the help of a potential field and a NLFFF extrapolation codes in a full-disk using HMI data as a boundary conditions. We compare projections of the resulting magnetic field lines solutions with full-disk coronal images from the Atmospheric Imaging Assembly (SDO/AIA) for both models. This study has found that the NLFFF model reconstructs the magnetic configuration better than the potential field model. We have concluded that much of trans-equatorial loops connecting the two solar hemispheres are current-free.
description: 5 figures, Submitted to Solar Physics Journal
Ant Farm Video
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021

description: DVDs, "Classics of video art from the 1970's by the notorious Art and Architecture group: Cadillac Ranch 1974/1994, Media Burn, Ant Farm's Dirty Dishes, Inflatables Illustrated, World's Longest Bridge, Time Capsule 1972-1984, OFF-AIR Australia" : 2 copies
Assessing molecular line diagnostics of triggered star formation using synthetic observations
Creators: name: Haworth, Thomas J.
name: Harries, Tim J.
name: Acreman, David M.
name: Rundle, David A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We investigate observational signatures of triggered star formation in bright rimmed clouds (BRCs) by using molecular line transfer calculations based on radiation-hydrodynamic radiatively-driven-implosion models. We find that for BRCs the separation in velocity between the line profile peak of an optically thick and an optically thin line is determined by both the observer viewing angle and the density of the shell driving into the cloud. In agreement with observations, we find that most BRC line profiles are symmetric and that asymmetries can be either red or blue, in contrast to the blue-dominance expected for a collapsing cloud. Asymmetries in the line profiles arise when an optically thick line is dominated by the shell and an optically thin line is dominated by the cloud interior to the shell. The asymmetries are red or blue depending on whether the shell is moving towards or away from the observer respectively. Using the known motions of the molecular gas in our models we rule out the envelope expansion with core collapse mechanism as the cause of the lack of blue-asymmetry in our simulated observations. We show that the absence of a strong photon dominated region (PDR) around a BRC may not rule out the presence of triggered star formation: if the BRC line profile has a strong blue component then the shell is expected to be driving towards the observer, suggesting that the cloud is being viewed from behind and the PDR is obstructed. This could explain why BRCs such as SFO 80, 81 and 86 have a blue secondary peak and only a weak PDR inferred at 8 microns. Finally we also test the use of 12CO, 13CO and C18O as diagnostics of cloud mass, temperature and column density. We find that the inferred conditions are in reasonable agreement with those from the models.
description: 17 pages, Accepted for publication in MNRAS, revision following editor proof
Space, Land and Time, Underground Adventures with Ant Farm: A documentary about the 1970s architecture collective
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Architects

description: An independent video documentary, this is the first film to delve into the work of the renegade 1970s art/architecture collective Ant Farm, best known for its iconic land-art piece Cadillac Ranch in Amarillo, TX. Radical architects, video pioneers, and mordantly funny cultural commentators, the Ant Farmers created a body of deeply subversive work that questioned everything by posing a set of creative and comedic alternatives.
title: Корпоративная культура
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: В пособии на основе широкого круга отечественных и зарубежных источников рассматриваются теоретические, методические и практические вопросы корпоративной культуры и корпоративной этики. Раскрывается их природа, сущность и основные принципы. Анализируются этические, риторические основы корпоративной культуры. Особое внимание уделено анализу процесса формирования и поддержания корпоративной культуры. Кроме того, подробно рассмотрены проблемы управленческой культуры менеджера и культуры управленческого общения. Для студентов, магистрантов, аспирантов, а также преподавателей дисциплин «Менеджмент», «Корпоративная культура», «Этика деловых отношений»; может быть полезно для деловых кругов, работников органов исполнительной и законодательной власти, средств массовой информации.
Maskless and targeted creation of arrays of colour centres in diamond using focused ion beam technology
Creators: name: Lesik, Margarita
name: Spinicelli, Piernicola
name: Pezzagna, Sébastien
name: Happel, Patrick
name: Jacques, Vincent
name: Salord, Olivier
name: Rasser, Bernard
name: Delobbe, Anne
name: Sudraud, Pierre
name: Tallaire, Alexandre
name: Meijer, Jan
name: Roch, Jean-François
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The creation of nitrogen-vacancy centres in diamond is nowadays well controlled using nitrogen implantation and annealing. Although the high-resolution placement of NV centres has been demonstrated using either collimation through pierced AFM tips or masks with apertures made by electron beam lithography, a targeted implantation into pre-defined structures in diamond may not be achieved using these techniques. We show that a beam of nitrogen ions can be focused to approximately 100 nm using focused ion beam (FIB) technology. The nitrogen ion beam is produced using an electron cyclotron resonance (ECR) plasma source. Combined with a scanning electron microscope, the nitrogen-FIB offers new possibilities for the targeted creation of single defects in diamond. This maskless technology is suitable for example for the creation of optical centres in the cavities of photonic crystals or in diamond tips for scanning magnetometry. Finally, we further show that by changing the gas source from nitrogen to xenon, standard FIB milling capabilities are also available within the same tool.
title: Логистика
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Данное учебное пособие подготовлено в соответствии с программой одноименной дисциплины, изучение которой предусмотрено Федеральным государственным образовательным стандартом по направлению бакалавриата «Менеджмент». Материал рассматривается в теоретико-методологическом, методическом аспектах.
A First Step Towards Behavioral Coaching for Managing Stress: A Case Study on Optimal Policy Estimation with Multi-stage Threshold Q-learning
Creators: name: Hu, Xinyu
name: Hsueh, Pei-Yun S.
name: Chen, Ching-Hua
name: Diaz, Keith
name: Cheung, Ying Kuen
name: Qian, Min
Publisher: name: Columbia University
Year: 2018
Subjects: Stress management
Cardiovascular system--Diseases--Prevention
Health

description: Psychological stress is a major contributor to the adoption of unhealthy behaviors, which in turn accounts for 41% of global cardiovascular disease burden. While the proliferation of mobile health apps has offered promise to stress management, these apps do not provide micro-level feedback with regard to how to adjust one's behaviors to achieve a desired health outcome. In this paper, we formulate the task of multi-stage stress management as a sequential decision-making problem and explore the application of reinforcement learning to provide micro-level feedback for stress reduction. Specifically, we incorporate a multi-stage threshold selection into Q-learning to derive an interpretable form of a recommendation policy for behavioral coaching. We apply this method on an observational dataset that contains Fitbit ActiGraph measurements and self-reported stress levels. The estimated policy is then used to understand how exercise patterns may affect users' psychological stress levels and to perform coaching more effectively.
The effectiveness of forensic interview procedures with child sexual abuse victims: A systematic review
Creators: name: Fernandes, Delfina
name: Gomes, João
name: Matos, Marlene
name: Albuquerque, Pedro
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Child sexual abuse (CSA) victimization is currently a significant social and scientific concern due to the negative consequences for victims, the family system, and society. The CSA victims' testimony, obtained through forensic interviews, is necessary for the judicial procedure and is essential to ensure their protection and safeguarding. Therefore, different procedures have been developed to avoid secondary victimization and improve the quantity and quality of the information provided by the victims. Thus, we intend to analyze the effectiveness of the forensic interview procedures to collect the CSA victims' testimony.
Performance Analysis of MIPv6 protocol in Handover Process in different working cases Using OPNET Modeler ® 14.0
Creators: name: Alwer, Abdulkader
Publisher: name: figshare
Year: 2021
Subjects: subject: 80503 Networking and Communications
subject: FOS: Computer and information sciences
subject: 100503 Computer Communications Networks
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 100504 Data Communications

description: Mobile IPv6 enables a Mobile Node to maintain its connectivity to the Internet when moving from one Access Router to another, a process referred to as handover. MIPv6 defined two working cases of communication between Mobile Node (MN) and correspondent Node (CN) which are bidirectional-tunnel mode and Route Optimization. In bidirectional-tunnel Mode, Data is routed between MN and CN through Tunnelling Method that established between HA and MN, and Data will be delivered between MN and HA in this tunnel. Whereas in Route Optimization Data will be sent between MN and CN directly; but implementing this case required that the two communicated node supporting MIPv6. In this paper, we focus on comparing performance of MIPv6 in this two cases during Handover process especially in route Optimization case using OPNET Modeller ® 14.0 in Real Time cases with consideration of QoS Requirement during this movement and finally analysis the results. From the evaluation results using OPNET Modeller ® 14.0, we can see that working in the Route Optimization case can achieve low handover latency and low packet delay comparing with bidirectional –tunnel Mode.
D5.3 Consumer and public acceptance assessment report
Creators: name: Davidis, Bas
name: Vis, Martijn
name: Alasis, Christos
name: Maachi Haddou, Meriem
Publisher: name: Zenodo
Year: 2022
Subjects: social acceptance
bioenergy
consumers

description: Successful implementation of bioenergy systems such as SmartCHP can be supported by understanding the social acceptance of bioenergy CHP and/or bioenergy systems in general in a given country. In this report, the social acceptance of bioenergy systems has been assessed within five relevant focus countries in the EU, i.e. Sweden, Netherlands, Romania, Croatia and Greece.
title: 	Budynek Wydziału Architektury i Wydziału Inżynierii Zarządzania jako wstęp do zrównoważonego rozwoju kampusu „Warta” Politechniki Poznańskiej
Creators: name: Rosolski, Sławomir
name: Rutkowski, Michał
name: Wójtowicz, Jakub
Publisher: name: Publishing House of Poznan University of Technology
Year: 2023

description: Zeszyty Naukowe Politechniki Poznańskiej. Architektura, Urbanistyka, Architektura Wnętrz, 14, 105-118
FIBROBLAST GROWTH FACTOR BINDING PROTEIN 1 (FGFBP1) CONTRIBUTES IN THE ESTABLISHMENT AND MAINTENANCE OF THE BLOOD BRAIN BARRIER
Creators: name: COTTARELLI, AZZURRA
Publisher: name: Universit� degli Studi di Milano
Year: 2015

description: The Blood Brain Barrier (BBB) is a highly specialized vascular structure whose aim is to tightly regulate the permeability between the blood flow and the Central Nervous System (CNS). To this purpose, the ECs in the brain need to present some peculiar features: the presence of high-resistance tight junctions (TJs) to block paracellular permeability, the lack of fenestrations, and the expression of some specific transmembrane transporters to selectively allow the entrance of nutrients and the exit of toxic metabolites. The high level of specialization of the brain microvasculature is obtained as a result of the interaction of the endothelial compartment with the other components of the so-called NeuroVascular Unit (NVU), such as the Basement Membrane (BM), pericytes and astrocyte end-feet. The canonical Wnt/?-catenin pathway, that is specifically activated in CNS vessels during development, regulates BBB initiation and maintenance. Moreover, inactivation of this pathway in vivo leads to angiogenic defects in the CNS and not in other vascular regions. Affymetrix analysis previously performed in our group provided a list of genes whose transcription is selectively regulated upon Wnt3a stimulation in murine primary ECs isolated from brain (bMEC). One of the most upregulated transcripts is that of Fibroblast Growth Factor Binding Protein 1 (FGFBP1) gene. FGFBP1 is a cargo protein that, after being secreted in the extracellular matrix (ECM), is able to non-covalently bind the FGF immobilized in the ECM and to mobilize it, protecting it from degradation and presenting it to FGF tyrosine-kinase receptor on the cell membrane. Given the capability of Wnt3a stimulation to selectively induce FGFBP1 expression in brain ECs, we hypothesized that this protein could be involved in the process of initiation and/or maturation of the BBB. In this work, we demonstrate in vivo in the zebrafish model that FGFBP1 knock down by morpholino presents vascular abnormalities in the brain and in the trunk, together with cerebral hemorrhages and impaired permeability. Taking advantage of the endothelial-specific FGFBP1 knock out murine model, we further demonstrate that inhibition of endothelial FGFBP1 expression affects brain vascular development, causing vascular defects and increased BBB permeability and also influencing the number of pericytes and the composition of the BM. Finally, we show in vitro that FGFBP1 absence promotes a ?tip-like? phenotype and an increase in the expression of Plvap in bMECs. In conclusion, our work proposes a novel role for FGFBP1 in the maintenance of the properties of the BBB and in the regulation of the complex interactions of the endothelial compartment with the other components of the NVU.
Spinor Frenet Equations in Three Dimensional Lie Groups
Creators: name: Okuyucu, O. Zeki
name: Yıldız, Ö. Gökmen
name: Tosun, Murat
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 11A66, 22E15

description: In this paper, we study spinor Frenet equations in three dimensional Lie Groups with a bi-invariant metric. Also, we obtain spinor Frenet equations for special cases of three dimensional Lie groups.
description: 10 pages
Brane cosmology from observational surveys and its comparison with standard FRW cosmology
Creators: name: Astashenok, A. V.
name: Elizalde, E.
name: de Haro, J.
name: Odintsov, S. D.
name: Yurov, A. V.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Several dark energy models on the brane are investigated. They are compared with corresponding theories in the frame of 4d Friedmann-Robertson-Walker cosmology. To constrain the parameters of the models considered, recent observational data, including SNIa apparent magnitude measurements, baryon acoustic oscillation results, Hubble parameter evolution data and matter density perturbations are used. Explicit formulas of the so-called {\it state-finder} parameters in teleparallel theories are obtained that could be useful to test these models and to establish a link between Loop Quantum Cosmology and Brane Cosmology. It is concluded that a joint analysis as the one developed here allows to estimate, in a very convenient way, possible deviation of the real universe cosmology from the standard Friedmann-Robertson-Walker one.
description: 19 pages, 6 figures. arXiv admin note: text overlap with arXiv:1206.2192
title: Маркетинг взаимоотношений на потребительском рынке электронной торговли: концептуальный подход и инструментарий сетевых взаимодействий
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Российской потребительский рынок сегодня находится в состоянии трансформации, определяющее на которую оказывают движущие силы глобализации и развитие информационных и коммуникационных технологий. В этих условиях изменению подвергаются модели поведения и факторы мотивации личности, а вместе с ними модифицируется вся совокупность экономических отношений рыночных субъектов, что приводит к необходимости совершенствования подходов в маркетинговой деятельности и маркетингового инструментария. В представляемом исследовании обобщены теоретико-методологические основы маркетинговой деятельности на потребительском рынке в сфере электронной торговли, выявлены ключевые факторы и рассмотрены особенности поведения потребителей на рынке электронной торговли, предлагаются подходы и методики оценки обоснованности выбора сетевого маркетингового инструментария. Работа адресована ученым и специалистам-практикам в сфере маркетинга и электронной торговли, студентам, магистрантам и аспирантам экономических специальностей, а также широкой публике, интересующейся вопросами маркетинга.
Resting-State Functional Connectivity in Late-Life Depression: Higher Global Connectivity and More Long Distance Connections
Creators: name: Bohr, Iwo Jerzy
name: Kenny, Eva
name: Blamire, Andrew
name: O'Brien, John T.
name: Thomas, Alan J.
name: Richardson, Jonathan
name: Kaiser, Marcus
Publisher: name: arXiv
Year: 2013
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: Functional magnetic resonance imaging recordings in the resting-state (RS) from the human brain are characterized by spontaneous low-frequency fluctuations in the blood oxygenation level dependent signal that reveal functional connectivity (FC) via their spatial synchronicity. This RS study applied network analysis to compare FC between late-life depression (LLD) patients and control subjects. Raw cross-correlation matrices (CM) for LLD were characterized by higher FC. We analyzed the small-world (SW) and modular organization of these networks consisting of 110 nodes each as well as the connectivity patterns of individual nodes of the basal ganglia. Topological network measures showed no significant differences between groups. The composition of top hubs was similar between LLD and control subjects, however in the LLD group posterior medial-parietal regions were more highly connected compared to controls. In LLD, a number of brain regions showed connections with more distant neighbors leading to an increase of the average Euclidean distance between connected regions compared to controls. In addition, right caudate nucleus connectivity was more diffuse in LLD. In summary, LLD was associated with overall increased FC strength and changes in the average distance between connected nodes, but did not lead to global changes in SW or modular organization.
title: Маркетинг территорий
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Учебное пособие предназначено для обучающихся по направлению 38.03.04 «Государственное муниципальное управление», 38.04.04 «Государственное муниципальное управление», специальности 38.05.02 «Таможенное дело» и рекомендуется для самостоятельного изучения одноименной дисциплины, при подготовке к промежуточной аттестации, курсовому проектированию. На материалах сравнительного анализа российской и зарубежной практики авторы рассматривают проблемы маркетинга территорий — специфику продвижения стран, городов, регионов и сельских поселений. Книга адресована преподавателям, студентам, а также практикам в области маркетинга территорий и регионального управления.
SURUNKALI ATROFIK RINITNI ZAMONAVIY DAVOLASH USULLARINI TAKOMILLASHTIRISH
Creators: name: Xushvakova, Nilufar
name: Ochilov, Toir
Publisher: name: Zenodo
Year: 2023

description: Atrofik rinit – burun bushlig'ining surunkali yallig'lanish jarayoni bo'lib, burun shilliq qavatining atrofiyasi bilan tavsiflanadi, shuningdek yallig'lanish jarayoni bezlar va burun chig'anoqlariga ham ta'sir qiladi. Surunkali atrofik rinitning etiologiyasi hali ham noaniq bo'lib qolmoqda, tashxis bemorning shikoyatlari va obyektiv tekshiruv ma'lumotlariga (shu jumladan burun bo'shlig'ining endoskopiyasi) asoslanadi. Surunkali atrofik rinitni davolash asosan simptomatik bo'lib, turli xil burun spreylarini, shuningdek, burun bo'shlig'ini tozalashni va qo'llashni o'z ichiga oladi.
title: Математика. Математическая статистика. Ч. 6
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: В пособии приведены необходимые теоретические сведения и формулы, даны решения типовых задач, приведены задачи для самостоятельного решения, сопровождающиеся указаниями. В конце каждого параграфа предлагаются вопросы для самоконтроля и задачи для самостоятельной работы. Учебное пособие составлено в помощь студентам при изучении тем по математической статистики.
The influence of the secondary electron induced asymmetry on the Electrical Asymmetry Effect in capacitively coupled plasmas
Creators: name: Korolov, Ihor
name: Derzsi, Aranka
name: Donko, Zoltan
name: Schulze, Julian
Publisher: name: arXiv
Year: 2013
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In geometrically symmetric capacitive radio-frequency plasmas driven by two consecutive harmonics a dc self-bias can be generated as a function of the phase shift between the driving frequencies via the Electrical Asymmetry Effect (EAE). Recently the Secondary Electron Asymmetry Effect (SEAE) was discovered (T. Lafleur, P. Chabert and J.P. Booth, J. Phys. D: Appl. Phys. 46 135201 (2013)): unequal secondary electron emission coefficients at both electrodes were found to induce an asymmetry in single frequency capacitive plasmas. Here, we investigate the simultaneous presence of both effects, i.e. a dual-frequency plasma driven by two consecutive harmonics with different electrode materials. We find, that the superposition of the EAE and the SEAE is non-linear, i.e. the asymmetries generated by each individual effect do not simply add up. The control ranges of the dc self-bias and the mean ion energy can be enlarged, if both effects are combined.
title: Математика. Теория вероятностей. Ч. 5
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: В пособии приведены необходимые теоретические сведения и формулы, даны решения типовых задач, приведены задачи для самостоятельного решения, сопровождающиеся указаниями. В конце каждой главы предлагаются вопросы для самопроверки усвоения материала, а также предлагаются задачи для самостоятельной работы. Учебное пособие предназначено для студентов экономических специальностей при изучении тем по теории вероятностей.
Link Scheduling for Multiple Multicast Sessions in Distributed Wireless Networks
Creators: name: Argyriou, Antonios
Publisher: name: arXiv
Year: 2013
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: In this letter we investigate link scheduling algorithms for throughput maximization in multicast wireless networks. According to our system model, each source node transmits to a multicast group that resides one hop away. We adopt the physical interference model to reflect the aggregate signal to interference and noise ratio (SINR) at each node of the multicast group. We present an ILP formulation of the aforementioned problem. The basic feature of the problem formulation is that it decomposes the single multicast session into the corresponding point-to-point links. The rationale is that a solution algorithm has more flexibility regarding the scheduling options for individual nodes. The extended MILP problem that also considers power control is solved with LP relaxation. Performance results for both the ILP and MILP problems are obtained for different traffic loads and different number of nodes per multicast group.
ONSET OF ANEMIA IN PULMONARY DISEASES: ROLE OF HYPOXIA, OXIDATIVE STRESS, IRON METABOLISM AND HEMATOPOIETIC REGULATORS
Creators: name: OTTOLENGHI, SARA
Publisher: name: Universit� degli Studi di Milano
Year: 2021

description: BACKGROUND: In patients affected by severe hypoxia, such as those with Acute Respiratory Distress Syndrome (ARDS), an acute condition characterized by sudden onset of severe hypoxemia and a severe manifestation of COVID19, anemia is a common complication. It remains to be established weather iron metabolism, especially hepcidin, and oxidative stress are involved in negatively interfering with physiological hematopoietic compensatory mechanisms to hypoxia. AIMS: - To investigate etiology and progression of anemia in ARDS patients, through biomarkers of inflammation, iron metabolism and oxidative stress. - To identify the effects of increased hepcidin and the potentially protective effects of erythropoietin (EPO) in the energetic metabolism of lung and brain cells. METHODS: We collected blood samples at three timepoints from 20 ARDS patients: at the diagnosis (T0), when hemoglobin (Hb) was 3 g/dl less than T0 or <8 g/dL (T1), and two days after T1 (T2). Twenty ambulatory chronic obstructive pulmonary disease (COPD) patients were recruited to compare with non-anemic chronic hypoxia and ten non-hypoxic volunteers represented the control group. We reproduced hypoxia and inflammation in hypoxic lung A549 cells treated with lipopolysaccharide (LPS), and mitochondrial damage in neural SHSY5Y cells. The effect of hepcidin treatment and EPO on energetic metabolism was evaluated by measuring oxygen consumption and extracellular acidification rate (Seahorse technology). RESULTS: In ARDS patients, [Hb] decreased within 7-10 days after T0. We observed that ARDS induced higher IL6, hepcidin and malondialdehyde (MDA) with respect to both COPD and controls. The antioxidant barrier (ferric reducing antioxidant power test, FRAP) was weakened from T0 to T1. COVID19 ARDS values were similar to non-COVID ARDS, except for higher hepcidin and non-transferrin-bound iron (NTBI). EPO values were unchanged despite hypoxia. In hypoxic A549 cells, LPS decreased viability and, in combination with hepcidin, decreased mitochondrial respiration and increased the glycolytic rate. In SHSY5Y challenged cells, EPO partially rescued mitochondrial damage and increased glycolysis. CONCLUSIONS: ARDS is characterized by systemic release of inflammatory mediators, which negatively interfere with the hematopoietic adaptation to hypoxia. Oxidative stress and inflammation increase hepcidin, which induces a dysregulation in iron metabolism, with anemia and mitochondrial damage.
Prospective applications of optical quantum memories
Creators: name: Bussieres, Felix
name: Sangouard, Nicolas
name: Afzelius, Mikael
name: de Riedmatten, Hugues
name: Simon, Christoph
name: Tittel, Wolfgang
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: An optical quantum memory can be broadly defined as a system capable of storing a useful quantum state through interaction with light at optical frequencies. During the last decade, intense research was devoted to their development, mostly with the aim of fulfilling the requirements of their first two applications, namely quantum repeaters and linear-optical quantum computation. A better understanding of those requirements then motivated several different experimental approaches. Along the way, other exciting applications emerged, such as as quantum metrology, single-photon detection, tests of the foundations of quantum physics, device-independent quantum information processing and nonlinear processing of quantum information. Here we review several prospective applications of optical quantum memories with a focus on recent experimental achievements pertaining to these applications. This review highlights that optical quantum memories have become essential for the development of optical quantum information processing.
description: Review paper. Comments are welcome!
DETERMINING THE EFFECTIVENESS OF THE TREATMENT METHOD IN PATIENTS WITH ODONTOGENIC SINUSITIS
Creators: name: Khushvakova, Nilufar
name: Burkhanov, Ulugbek
name: Mo'minov, Akbarali
Publisher: name: Zenodo
Year: 2023

description: The article presents the development of diagnostic and treatment tactics for patients with odontogenic sinusitis, complicated by incorrect endodontic treatment of teeth in the upper jaw, as well as the use of low-intensity laser therapy.
title: Налоги и налогообложение. Теория налогов и налоговая система
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Учебное пособие группирует принципиальные элементы теории налогов, характеризует специфические условия установления этих элементов для России. Классификация платежей государству, функций налогов и принципов налогообложения позволяют перейти от общей теории налоговых систем к выбору конкретных условий налогообложения. Исторические аспекты развития налогообложения в целом и теории налогов в частности подводят к постановке целей развития налоговой системы России. Учебное пособие раскрывает элементы налоговой системы и механизм их взаимодействия, характеризует систему налогов и сборов России. Анализ и оценка налогового бремени различных категорий плательщиков позволяют провести сравнительный анализ фактического и оптимального налогового бремени на микроуровне. Учебное пособие предназначено для бакалавров, обучающихся по направлению «Государственное и муниципальное управление». Материалы учебного пособия могут быть полезными для бакалавров по направлениям «Экономика» и «Менеджмент», специалистам в области налогообложения, должностным лицам налоговых органов, налоговым консультантам, налогоплательщикам всех категорий. Автор продолжает исследования с целью внесения дополнений в последующие издания книги.
title: Основы научных исследований
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Учебное пособие написано в соответствии с Государственным стандартом РФ по дисциплине «Основы научных исследований». В пособии изложены представления о науке как специфической системе знаний, форме духовного производства и социальном институте, общих закономерностях ее развития, роли в жизни человека и общества; об уровнях и методологии. Предназначено для студентов гуманитарных и экономических специальностей высших учебных заведений всех форм обучения.
Carpal tunnel syndrome: Etiology, diagnosis, and management
Creators: name: José Antonio Velasco Cabrera M.D.
name: Yunuén Maqueda Sánchez M.D.
name: Arturo Romero Macías M.D.
name: Rosalia Karina González Pérez M.D.
name: Luis Eduardo Kern García M.D.
name: José Enrique Pons Taracena M.D.
name: Zully Desireé Paz López M.D.
name: Jehieli Pérez Bravo M.D.
name: Ian Ruiz Jurado M.D.
name: Lorenzo Arturo Mendoza Brito M.D.
name: Julio Alejandro Sánchez Banderas M.D.
Publisher: name: Zenodo
Year: 2023

description: Background
Carpal tunnel syndrome (CTS) is a common medical condition characterized by compression of the median nerve in the carpal tunnel. This article reviews the etiology, clinical presentation, diagnostic methods, and management strategies of CTS. The role of recent advances in the understanding and treatment of CTS is also discussed.
 
Keywords: Carpal tunnel syndrome, nerve compression syndrome.