cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Redshift Search Receiver 3 mm Wavelength Spectra of 10 Galaxies
Creators: name: Snell, Ronald L.
name: Narayanan, Gopal
name: Yun, Min S.
name: Heyer, Mark
name: Chung, Aeree
name: Irvine, William M.
name: Erickson, Neal R.
name: Liu, Guilin
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The 3 mm wavelength spectra of 10 galaxies have been obtained at the Five College Radio Astronomy Observatory using a new, very broadband receiver and spectrometer, called the Redshift Search Receiver (RSR). The RSR has an instantaneous bandwidth of 37 GHz covering frequencies from 74 to 111 GHz, and has a spectral resolution of 31 MHz (~100 km/s). During tests of the RSR on the FCRAO 14 m telescope the complete 3 mm spectra of the central regions of NGC 253, Maffei 2, NGC1068, IC 342, M82, NGC 3079, NGC 3690, NGC 4258, Arp 220 and NGC 6240 were obtained. Within the wavelength band covered by the RSR, 20 spectral lines from 14 different atomic and molecular species were detected. Based on simultaneous fits to the spectrum of each galaxy, a number of key molecular line ratios are derived. A simple model which assumes the emission arises from an ensemble of Milky Way-like Giant Nolecular Cloud cores can adequately fit the observed line ratios using molecular abundances based on Galactic molecular cloud cores. Variations seen in some line ratios, such as 13CO/HCN and HCO+/HCN, can be explained if the mean density of the molecular gas varies from galaxy to galaxy. However, NGC 3690, NGC 4258 and NGC 6240 show very large HCO+/HCN ratios and require significant abundance enhancement of HCO+ over HCN, possible due to the proximity to active galactic nucleus activity. Finally, the mass of dense molecular gas is estimated and we infer that 25-85 % of the total molecular gas in the central regions of these galaxies must have densities greater than 10^4 cm^-3.
description: accepted for publication in A.J
title: ÐÑÐ¾ÐµÐºÑ Ð¼Ð°Ð»Ð¾ÑÑÐ°Ð¶Ð½Ð¾Ð³Ð¾ Ð·Ð´Ð°Ð½Ð¸Ñ Ñ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸ÐµÐ¼ ÑÐµÐ¿Ð»Ð¾Ð²ÑÑ Ñ Ð°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: A project of a low-rise residential building has been developed using software systems to determine building thermal characteristics
Creators: name: ÐÐ¸ÑÐ°Ð¹Ð»Ð¾Ð², ÐÐ¸ÑÐ¸Ð»Ð»
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2022
Subjects: Ð¼Ð°Ð»Ð¾ÑÑÐ°Ð¶Ð½ÑÐ¹ Ð¶Ð¸Ð»Ð¾Ð¹ Ð´Ð¾Ð¼
Ð¾Ñ ÑÐ°Ð½Ð° ÑÑÑÐ´Ð°
Ð¾Ñ ÑÐ°Ð½Ð° Ð¾ÐºÑÑÐ¶Ð°ÑÑÐµÐ¹ ÑÑÐµÐ´Ñ
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ÑÐ°ÑÑÐµÑÐ½ÑÐµ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÑ
low-rising residential building
labor safety
environmental protection
heat loss calculations
calculation software

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ Ð¿ÑÐ¾ÐµÐºÑ Ð¼Ð°Ð»Ð¾ÑÑÐ°Ð¶Ð½Ð¾Ð³Ð¾ Ð¶Ð¸Ð»Ð¾Ð³Ð¾ Ð´Ð¾Ð¼Ð° Ñ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸ÐµÐ¼ ÑÐµÐ¿Ð»Ð¾Ð²ÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº Ð¿ÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½ÑÑ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ¾Ð². Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ Ð´Ð»Ñ ÑÑÐµÐ¿Ð»ÐµÐ½Ð¸Ñ Ð¾Ð³ÑÐ°Ð¶Ð´Ð°ÑÑÐ¸Ñ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¹, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿Ð¾ Ð¾ÑÑÐ°Ð½Ðµ ÑÑÑÐ´Ð° Ð¸ Ð¾ÑÑÐ°Ð½Ðµ Ð¾ÐºÑÑÐ¶Ð°ÑÑÐµÐ¹ ÑÑÐµÐ´Ñ. ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð¿Ð¾Ð´Ð±Ð¾Ñ Ð¾ÑÐ¾Ð¿Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð´Ð»Ñ ÑÐ¼ÐµÐ½ÑÑÐµÐ½Ð¸Ñ Ð²Ð»Ð¸ÑÐ½Ð¸Ñ Ð½Ð° Ð¾ÐºÑÑÐ¶Ð°ÑÑÑÑ ÑÑÐµÐ´Ñ. ÐÑÐ¸Ð½ÑÑÑ ÐºÐ¾Ð½ÐºÑÐµÑÐ½ÑÐµ Ð°ÑÑÐ¸ÑÐµÐºÑÑÑÐ½ÑÐµ Ð¸ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½ÑÐµ ÑÐµÑÐµÐ½Ð¸Ñ Ð´Ð»Ñ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÑÐµÐ¼Ð¾Ð³Ð¾ Ð¾Ð±ÑÐµÐºÑÐ°, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ñ ÑÐ½ÐµÑÐ³Ð¾ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð·Ð´Ð°Ð½Ð¸Ñ.
description: In this paper, a project of a low-rise residential building has been developed using software systems to determine building thermal characteristics. Various materials for insulation of enclosing structures, as well as measures for labor protection and environmental protection are considered. The selection of heating equipment to reduce the impact on the environment has been carried out. Specific architectural and design decisions were made for the projected object, and the energy efficiency index of the building was calculated.
Synthetic photometry for carbon-rich giants. V. Effects of grain-size-dependent dust opacities
Creators: name: Eriksson, Kjell
name: Höfner, Susanne
name: Aringer, Bernhard
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The properties and the evolution of asymptotic giant branch (AGB) stars are strongly influenced by their mass loss through a stellar wind. This is believed to be caused by radiation pressure due to the absorption and scattering of the stellar radiation by the dust grains formed in the atmosphere. The optical properties of dust are often estimated using the small particle limit (SPL) approximation, and it has been used frequently in modelling AGB stellar winds when performing radiation-hydrodynamics (RHD) simulations. We aim to investigate the effects of replacing the SPL approximation by detailed Mie calculations of the size-dependent opacities for grains of amorphous carbon forming in C-rich AGB star atmospheres. We performed RHD simulations for a large grid of carbon star atmosphere+wind models with different effective temperatures, luminosities, stellar masses, carbon excesses, and pulsation properties. Also, a posteriori radiative transfer calculations for many radial structures (snapshots) of these models were done, resulting in spectra and filter magnitudes. We find, when giving up the SPL approximation, the wind models become more strongly variable and more dominated by gusts, although the average mass-loss rates and outflow speeds do not change significantly; the increased radiative pressure on the dust throughout its formation zone does, however, result in smaller grains and lower condensation fractions (and thus higher gas-to-dust ratios). The photometric K magnitudes are generally brighter, but at V the effects of using size-dependent dust opacities are more complex: brighter for low mass-loss rates and dimmer for massive stellar winds. Given the large effects on spectra and photometric properties, it is necessary to use the detailed dust optical data instead of the simple SPL approximation in stellar atmosphere+wind modelling where dust is formed.
description: 14 pages, 24 figures. Accepted for publication in Astronomy \& Astrophysics
Additional file 2 of Criteria for assessing the quality of clinical practice guidelines in paediatrics and neonatology: a mixed-method study
Creators: name: Dagard, Joanna
name: Mazille-Orfanos, Nadia
name: Georgi, Nawras
name: Dechicha, Intissar
name: Carrault, Guy
name: Pladys, Patrick
name: Beuchée, Alain
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Additional file 2. Questionnaires.
Simulation of Classical Thermal States on a Quantum Computer: A Transfer Matrix Approach
Creators: name: Yung, Man-Hong
name: Nagaj, Daniel
name: Whitfield, James D.
name: Aspuru-Guzik, Alán
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a hybrid quantum-classical algorithm to simulate thermal states of a classical Hamiltonians on a quantum computer. Our scheme employs a sequence of locally controlled rotations, building up the desired state by adding qubits one at a time. We identify a class of classical models for which our method is efficient and avoids potential exponential overheads encountered by Grover-like or quantum Metropolis schemes. Our algorithm also gives an exponential advantage for 2D Ising models with magnetic field on a square lattice, compared with the previously known Zalka's algorithm.
description: 5 pages, 3 figures; (new in version 2: added new figure, title changed, rearranged paragraphs)
Additional file 3 of Criteria for assessing the quality of clinical practice guidelines in paediatrics and neonatology: a mixed-method study
Creators: name: Dagard, Joanna
name: Mazille-Orfanos, Nadia
name: Georgi, Nawras
name: Dechicha, Intissar
name: Carrault, Guy
name: Pladys, Patrick
name: Beuchée, Alain
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Additional file 3. Consolidated database.
Finitistic Weak Dimension of Commutative Arithmetical Rings
Creators: name: Couchot, Francois
Publisher: name: arXiv
Year: 2011
Subjects: subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics

description: It is proven that each commutative arithmetical ring $R$ has a finitistic weak dimension $\leq 2$. More precisely, this dimension is 0 if $R$ is locally IF, 1 if $R$ is locally semicoherent and not IF, and 2 in the other cases.
The Beckett effect : the work of Stan Douglas, Paul Chan, and Tania Bruguera
Creators: name: Sánchez, Marisa C.
Publisher: name: University of British Columbia
Year: 2024

description: This dissertation on the “Beckett effect” explores the continuing impact of Samuel Beckett’s literary and dramatic texts on contemporary art practices. Since the 1960s, visual artists working in a variety of media have turned to Beckett’s literary productions as sources. I propose that the mediating function of Beckett’s texts extends beyond influence to produce a plurality of functions in the visual arts, which I have identified as the “Beckett effect.” By setting influence aside, I am able to ask: what is the art historical and theoretical significance of the frequency of the use of Beckett’s texts within contemporary art practices? How have these texts dispersed across North American and European contemporary art practices? Exactly what do Beckett’s writings offer contemporary visual artists? More specifically, this dissertation focuses on the effect of Beckett's interventions into the works of three artists: Stan Douglas (b. 1960), Paul Chan (b. 1973), and Tania Bruguera (b. 1968). I first explore Beckett’s reverberations in the visual arts with particular attention to the dispersal of his texts among key artists beginning in the sixties. From there, I argue that Beckett’s oeuvre constitutes a critical intervention into our understanding of contemporary modes of being subjects. Using Beckett’s texts, Douglas, Chan and Bruguera made films, videos, multi-media installations, and theatrical adaptations that allow the viewer to experience the work of art as an immersion in both the historical sense of time and their own present predicament(s). As such, Beckett’s texts serve the visual artist as the means to negotiate between a socially engaged practice and the specific, political or social issue they seek to address. When these artists use Beckett, the work of art moves away from the primacy of vision so that the viewer’s contemporary political and social contexts may be considered.
Star-formation rate and stellar mass calibrations based on infrared photometry and their dependence on stellar population age and extinction
Creators: name: Kouroumpatzakis, Konstantinos
name: Zezas, Andreas
name: Kyritsis, Elias
name: Salim, Samir
name: Svoboda, Jiri
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The stellar mass ($M_\star$) and the star-formation rate (SFR) are among the most important features that characterize galaxies. Measuring these fundamental properties accurately is critical for understanding the present state of galaxies, and their history. This work explores the dependence of the IR emission of galaxies on their extinction, and the age of their stellar populations (SPs). It aims at providing accurate IR SFR and $M_\star$ calibrations that account for SP age and extinction while quantifying their scatter. We use the CIGALE spectral energy distribution (SED) fitting code to create models of galaxies with a wide range of star-formation histories, dust content, and interstellar medium properties. We fit the relations between $M_\star$ and SFR with IR and optical photometry of the model-galaxy SEDs with the MCMC method, and perform a machine-learning random forest analysis on the same data set in order to validate the latter. This work provides calibrations for the SFR using a combination of the WISE bands 1 and 3, or the JWST F200W and F2100W bands. It also provides mass-to-light ratio calibrations based on the WISE band-1, or the JWST band F200W, along with the optical $u-r$ or $g-r$ colors. These calibrations account for the biases attributed to the SP age, while they are given in the form of extinction-dependent and extinction-independent relations. They show robust estimations while minimizing the scatter and biases throughout a wide range of SFRs and stellar masses. The SFR calibration offers better results, especially in dust-free or passive galaxies where the contributions of old SPs or biases from the lack of dust are significant. Similarly, the $M_\star$ calibration yields significantly better results for dusty/high-SFR galaxies where dust emission can otherwise bias the estimations.
description: 18 pages, 10 figures. Accepted for publication in Astronomy & Astrophysics on 16 March 2023
title: PR-ÑÐ¾Ð¿ÑÐ¾Ð²Ð¾Ð¶Ð´ÐµÐ½Ð¸Ðµ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð° (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Â«ÐÑÑ Ð ÑÐ´ÐµÐ½ÐºÐ¾ Ð¡ÑÑÐ´Ð¸ÑÂ»)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: PR support of a communication agency (on the example of LLC "Art Rudenko Studio")
Creators: name: ÐÐ¾Ð¸ÑÐµÐµÐ²Ð°, ÐÐ»ÑÐ³Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: PR-ÑÐ¾Ð¿ÑÐ¾Ð²Ð¾Ð¶Ð´ÐµÐ½Ð¸Ðµ
ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ðµ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð¾
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ÑÐ¸ÑÐ¼ÐµÐ½Ð½ÑÐ¹ ÑÑÐ¸Ð»Ñ
Ð´Ð¸Ð·Ð°Ð¹Ð½-ÐºÐ¾Ð½ÑÐµÐ¿Ñ
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PR-support
communication agency
rebending
logo
firm style
design concept
development of advertising content
competition
polygraphy
portfolio
corporate identity

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð° ÑÑÑÐ½Ð¾ÑÑÑ PR-ÑÐ¾Ð¿ÑÐ¾Ð²Ð¾Ð¶Ð´ÐµÐ½Ð¸Ñ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð° Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð° ÐÐÐ Â«ÐÑÑ Ð ÑÐ´ÐµÐ½ÐºÐ¾ Ð¡ÑÑÐ´Ð¸ÑÂ», ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¼ÐµÑÐ¾Ð´Ñ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¹ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð°
Ñ ÐºÐ»Ð¸ÐµÐ½ÑÐ°Ð¼Ð¸, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÐºÐ¾Ð½ÐºÑÑÐµÐ½ÑÐ¾Ð² Ð½Ð° ÑÑÐ½ÐºÐµ, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ñ SWOT-
Ð¸ STEP-Ð°Ð½Ð°Ð»Ð¸Ð·Ñ Ð±Ð°Ð·Ð¸ÑÐ½Ð¾Ð³Ð¾ ÑÑÐ±ÑÐµÐºÑÐ°, Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ð¹ ÑÐ¸ÑÐ¼ÐµÐ½Ð½ÑÐ¹ ÑÑÐ¸Ð»Ñ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð°, ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ Ð½Ð¾Ð²ÑÐ¹ ÑÐ¸ÑÐ¼ÐµÐ½Ð½ÑÐ¹ ÑÑÐ¸Ð»Ñ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð°, Ð´Ð°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð½Ð¾Ð²Ð¾Ð³Ð¾ ÑÐ¸ÑÐ¼ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐ¸Ð»Ñ Ð¸ ÑÐ»ÑÑÑÐµÐ½Ð¸Ñ Ð¸Ð¼Ð¸Ð´Ð¶Ð° ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð°.
description: In this paper, the essence of PR support for a communication agency is described, the portrait of a communication agency LLC Â«Art Rudenko StudioÂ» is studied, the methods of communication between the agency and customers are examined, the market competitors are analyzed, SWOT- and STEP-analyzes of the company are carried out, the existing corporate identity of the agency is analyzed,
a new one is developed agency corporate identity; recommendations are given on the use of the new corporate identity and improving the image of the communication agency.
The conservation of an ethnographic multi-material shield made in Malaysia by the Dayak tribe: pictorial surface cleaning and feathers restoration
Creators: name: Sangiorgi, Nausicaa
name: Accorsi, Graziella
name: Coladonato, Maurizio
Publisher: name: Estudos de Conservação e Restauro
Year: 2019

description: Ethnographic artifacts are intrinsically fragile, due to the natural constituent materials degradation. A polychrome and polymateric ethnographic shield from Borneo, owned by the National Prehistoric Ethnographic Museum “Luigi Pigorini” in Rome, has been carried out to restoration regarded mainly the painted surface cleaning and the feathers recovery, following criteria such as adopting not invasive methods to preserve the original materials and using eco-sustainable products.
description: Estudos de Conservação e Restauro, n. 10 (2019): YOCOCU CONFERENCE 2019: 3rd International Conference of Green Conservation of Cultural Heritage
Hypergeometric $τ$ Function of the $q$-Painlevé Systems of Type $(A_2+A_1)^{(1)}$
Creators: name: Nakazono, Nobutaka
Publisher: name: arXiv
Year: 2010
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider a $q$-Painlevé III equation and a $q$-Painlevé II equation arising from a birational representation of the affine Weyl group of type $(A_2+A_1)^{(1)}$. We study their hypergeometric solutions on the level of $τ$ functions.
Modulo Bianco a tripla struttura by Vanna Nicolotti: recomposition of the structural unit and aesthetic of a work created with the “cutting technique” on canvas
Creators: name: Picciolli, Lodovica
name: Vanghi, Lucia
Publisher: name: Estudos de Conservação e Restauro
Year: 2019

description: Modulo bianco a tripla struttura was made in 1970 by Vanna Nicolotti. The artist, close to the milanese Spatialism of Lucio Fontana, used the technique of cutting canvas in constant search for tridimensionality and geometric perfection through overlapping cut canvases. This technique caused conservation issues and the work wasn’t exposable anymore due its fragility and deterioration. Vanna Nicolotti therefore recommended the substitution of the front canvas or alternatively, as recommended by the conservator-restorer, it was decided to recompose the structural unit taking account of the artist’s poetics. The lacerated parts were reconnected after Agar-Agar gel moistening and by trecker method.
description: Estudos de Conservação e Restauro, n. 10 (2019): YOCOCU CONFERENCE 2019: 3rd International Conference of Green Conservation of Cultural Heritage
The 3D Velocity Structure of the Thick Disk from SPM4 and RAVE DR2
Creators: name: Casetti-Dinescu, D. I.
name: Girard, T. M.
name: Korchagin, V. I.
name: van Altena, W. F
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We analyze the 3D kinematics of a sample of $\sim 4400$ red clump stars ranging between 5 and 10 kpc from the Galactic center and up to 3 kpc from the Galactic plane. This sample is representative for the metal-rich ([Fe/H] = -0.6 to 0.5) thick disk. Absolute proper motions are from the fourth release of the Southern Proper Motion Program, and radial velocities from the second release of the Radial Velocity Experiment. The derived kinematical properties of the thick disk include: the rotational velocity gradient $\partial V_θ / \partial z = -25.2 \pm 2.1$ km s$^{-1}$ kpc$^{-1}$, velocity dispersions $(σ_{V_R}, σ_{V_θ}, σ_{V_z})|_{z=1} = (70.4, 48.0, 36.2) \pm(4.1,8.3,4.0)$ km s$^{-1}$, and velocity-ellipsoid tilt angle $α_{Rz} = 8.6\arcdeg \pm 1.8 \arcdeg$. Our dynamical estimate of the thin-disk scale length is $R_{thin} = 2.0 \pm 0.4$ kpc and the thick-disk scale height is $z_{thick} = 0.7 \pm 0.1$ kpc. The observed orbital eccentricity distribution compared with those from four different models of the formation of the thick disk from Sales et al. favor the gas-rich merger model and the minor merger heating model. Interestingly, when referred to the currently accepted value of the LSR, stars more distant than 0.7 kpc from the Sun show a net average radial velocity of $13 \pm3 $ km s$^{-1}$. This result is seen in previous kinematical studiesusing other tracers at distances larger than $\sim 1$ kpc. We suggest this motion reflects an inward perturbation of the locally-defined LSR induced by the spiral density wave.
description: accepted for publication in ApJ
On the stability of a soft-wall model
Creators: name: Gherghetta, T.
name: Setzer, N.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the stability and fluctuations of a soft wall model that has an asymptotically AdS metric and a scalar field that has an asymptotically power-law dependence in the conformal coordinate. By imposing UV boundary conditions, the soft wall mass scale can be fixed to be near the TeV scale and causes the radion to no longer be massless. A hierarchy between the weak scale and the Planck scale can be generated for various particle spectrum behavior, although natural values only occur for a gravitational sector containing scalar fields that act like unparticles. In addition, if bulk Standard Model fields have nonstandard couplings to the gravitational sector, then a discrete particle spectrum can be realized in the nongravitational sector. This allows for the possibility of an unparticle solution to the hierarchy problem.
description: 17 pages, 1 figure; references added
A Hybrid 3D/2D Field Response Calculation for Liquid Argon Detectors with PCB Based Anode Plane
Creators: name: Martynenko, S.
name: Pietropaolo, F.
name: Viren, B.
name: Qian, X.
name: Chen, H.
name: Gao, S.
name: Gu, W.
name: Jo, J.
name: Kettell, S.
name: Li, Y.
name: Liu, H.
name: Nayak, N.
name: Yu, B.
name: Yu, H.
name: Zhang, C.
name: Kose, U.
name: Resnati, F.
name: Tufanli, S.
name: Boran, F.
name: Dolek, F.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Liquid Argon Time Projection Chamber (LArTPC) technology is commonly utilized in neutrino detector designs. It enables detailed reconstruction of neutrino events with high spatial precision and low energy threshold. Its field response (FR) model describes the time-dependent electric currents induced in the anode-plane electrodes when ionization electrons drift nearby. An accurate and precise FR is a crucial input to LArTPC detector simulations and charge reconstruction. Established LArTPC designs have been based on parallel wire planes. It allows accurate and computationally economic two-dimensional (2D) FR models utilizing the translational symmetry along the direction of the wires. Recently, novel LArTPC designs utilize electrodes formed on printed circuit board (PCB) in the shape of strips with through holes. The translational symmetry is no longer a good approximation near the electrodes and a new FR calculation that employs regions with three dimensions (3D) has been developed. Extending the 2D models to 3D would be computationally expensive. Fortuitously, the nature of strips with through holes allows for a computationally economic approach based on the finite-difference method (FDM). In this paper, we present a new software package "pochoir" that calculates LArTPC field response for these new strip-based anode designs. This package combines 3D calculations in the volume near the electrodes with 2D far-field solutions to achieve fast and precise field response computation. We apply the resulting FR to simulate and reconstruct samples of cosmic-ray muons and $^{39}$Ar decays from a Vertical Drift (VD) detector prototype operated at CERN. We find the difference between real and simulated data within 5 %. Current state-of-the-art LArTPC software requires a 2D FR which we provide by averaging over one dimension and estimate that variations lost in this average are smaller than 7 %.
description: 16 pages, 12 figures
Classical BI: Its Semantics and Proof Theory
Creators: name: Brotherston, James
name: Calcagno, Cristiano
Publisher: name: arXiv
Year: 2010
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: F.4.1

description: We present Classical BI (CBI), a new addition to the family of bunched logics which originates in O'Hearn and Pym's logic of bunched implications BI. CBI differs from existing bunched logics in that its multiplicative connectives behave classically rather than intuitionistically (including in particular a multiplicative version of classical negation). At the semantic level, CBI-formulas have the normal bunched logic reading as declarative statements about resources, but its resource models necessarily feature more structure than those for other bunched logics; principally, they satisfy the requirement that every resource has a unique dual. At the proof-theoretic level, a very natural formalism for CBI is provided by a display calculus à la Belnap, which can be seen as a generalisation of the bunched sequent calculus for BI. In this paper we formulate the aforementioned model theory and proof theory for CBI, and prove some fundamental results about the logic, most notably completeness of the proof theory with respect to the semantics.
description: 42 pages, 8 figures
A Magnetized Jet from a Massive Protostar
Creators: name: Carrasco-Gonzalez, Carlos
name: Rodriguez, Luis F.
name: Anglada, Guillem
name: Marti, Josep
name: Torrelles, Jose M.
name: Osorio, Mayra
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Synchrotron emission is commonly found in relativistic jets from active galactic nuclei (AGNs) and microquasars, but so far its presence in jets from young stellar objects (YSOs) has not been proved. Here, we present evidence of polarized synchrotron emission arising from the jet of a YSO. The apparent magnetic field, with strength of ~0.2 milligauss, is parallel to the jet axis, and the polarization degree increases towards the jet edges, as expected for a confining helical magnetic field configuration. These characteristics are similar to those found in AGN jets, hinting at a common origin of all astrophysical jets.
description: First published in Science on Nov 26, 2010 (vol. 330, pp.1209-1212). Includes Supporting Online Material. For original publication, see http://www.sciencemag.org/content/330/6008/1209.abstract?sid=4c98088f-eee1-4754-bfff-b5b468351e4b
The removal of Paraloid® coatings with aqueous based formulations. Practical case in frescoes from els Munts Roman villa (Catalonia)
Creators: name: Giné, Aleix Barberà
name: Ortega, Silvia Marín
name: Pons, Pere Rovira
Publisher: name: Estudos de Conservação e Restauro
Year: 2019

description: This is the report of a practical case regarding the removal of Paraloid® B72 coatings from Roman frescoes. During the archaeological excavation, the paintings had been consolidated with the application of cotton gauze with an acrylic resin. The article presents the results regarding the effectiveness of the removal of the acrylic resin and the analytical assessment of the possible presence of residues on the work of art. The removal of the acrylic resin was carried out with an aqueous gelled system emulsified with only 10% solvent. The selection of the solvent phase presents fewer toxic alternatives to traditional solvents.
description: Estudos de Conservação e Restauro, n. 10 (2019): YOCOCU CONFERENCE 2019: 3rd International Conference of Green Conservation of Cultural Heritage
Dynamical Hyperspectral Unmixing with Variational Recurrent Neural Networks
Creators: name: Borsoi, Ricardo Augusto
name: Imbiriba, Tales
name: Closas, Pau
Publisher: name: arXiv
Year: 2023
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Multitemporal hyperspectral unmixing (MTHU) is a fundamental tool in the analysis of hyperspectral image sequences. It reveals the dynamical evolution of the materials (endmembers) and of their proportions (abundances) in a given scene. However, adequately accounting for the spatial and temporal variability of the endmembers in MTHU is challenging, and has not been fully addressed so far in unsupervised frameworks. In this work, we propose an unsupervised MTHU algorithm based on variational recurrent neural networks. First, a stochastic model is proposed to represent both the dynamical evolution of the endmembers and their abundances, as well as the mixing process. Moreover, a new model based on a low-dimensional parametrization is used to represent spatial and temporal endmember variability, significantly reducing the amount of variables to be estimated. We propose to formulate MTHU as a Bayesian inference problem. However, the solution to this problem does not have an analytical solution due to the nonlinearity and non-Gaussianity of the model. Thus, we propose a solution based on deep variational inference, in which the posterior distribution of the estimated abundances and endmembers is represented by using a combination of recurrent neural networks and a physically motivated model. The parameters of the model are learned using stochastic backpropagation. Experimental results show that the proposed method outperforms state of the art MTHU algorithms.
Theory of Neutrino Masses and Mixing
Creators: name: Grimus, Walter
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We motivate the usage of finite groups as symmetries of the Lagrangian. After a presentation of basic group-theoretical concepts, we introduce the notion of characters and character tables in the context of irreducible representations and discuss their applications. We exemplify these theoretical concepts with the groups S_4 and A_4. Finally, we discuss the relation between tensor products of irreducible representations and Yukawa couplings and describe a model for tri-bimaximal lepton mixing based on A_4.
description: 23 pages, lecture presented at IV International Pontecorvo Neutrino Physics School, September 26 - October 6, 2010, Alushta, Crimea, Ukraine
Additional file 1 of Patterns of flea infestation in rodents and insectivores from intensified agro-ecosystems, Northwest Spain
Creators: name: Herrero-Cófreces, Silvia
name: Flechoso, Manuel Fabio
name: Rodríguez-Pastor, Ruth
name: Luque-Larena, Juan José
name: Mougeot, François
Publisher: name: figshare
Year: 2021
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Flea cumulative frequencies in the main small mammal host species. CAA, Ctenophthalmus apertus apertus; CAG, Ctenophthalmus apertus gilcolladoi; CB, Ctenophthalmus baeticus; NF, Nosopsyllus fasciatus; LT, Leptopsylla taschenbergi; RB, Rhadinopsylla beillardae. * Sample size too small (n = 1).
Comparative approach about adhesives for the intervention of polychrome on stone: the case of Ramon Llull’s Sepulchre
Creators: name: Rubio, Llucia Bosch
name: Cabezas, Manuel Jardón
name: Cortés, Marina Granero
name: Morelli, Philip Kron
Publisher: name: Estudos de Conservação e Restauro
Year: 2019

description: The sepulchre of the Blessed Ramon Llull is a XV century monument located in Palma (Mallorca, Spain). During the studies developed for the restoration project, remains of the original polychrome were discovered. Prolonged exposure to high levels of humidity and leaks were the main causes of the deterioration of the monument’s polychromies. The plaster layers lost cohesion and adhesion from the support, so they had to be treated. For the selection of the adhesive, the results obtained in the researches through the current scientific bibliography were analyzed. As a result of the comparative process, ammonium caseinate, Klucel H® and funori were selected, to be tested on the monument for their compatibility, stability, adhesive properties, low optical effects, re-treatability and low concentration. Finally, funori was the definitive product used, with which the desired results were obtained.
description: Estudos de Conservação e Restauro, n. 10 (2019): YOCOCU CONFERENCE 2019: 3rd International Conference of Green Conservation of Cultural Heritage
Detections of [C II] 158 $μ$m and [O III] 88 $μ$m in a Local Lyman Continuum Emitter, Mrk 54, and its Implications to High-redshift ALMA Studies
Creators: name: Ura, Ryota
name: Hashimoto, Takuya
name: Inoue, Akio K.
name: Fadda, Dario
name: Hayes, Matthew
name: Puschnig, Johannes
name: Zackrisson, Erik
name: Tamura, Yoichi
name: Matsuo, Hiroshi
name: Mawatari, Ken
name: Fudamoto, Yoshinobu
name: Hagimoto, Masato
name: Kuno, Nario
name: Sugahara, Yuma
name: Yamanaka, Satoshi
name: Bakx, Tom J. L. C.
name: Nakazato, Yurina
name: Usui, Mitsutaka
name: Yajima, Hidenobu
name: Yoshida, Naoki
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present integral field, far-infrared (FIR) spectroscopy of Mrk 54, a local Lyman Continuum Emitter (LCE), obtained with FIFI-LS on the Stratospheric Observatory for Infrared Astronomy. This is only the second time, after Haro 11, that [C II] 158 $μ$m and [O III] 88 $μ$m spectroscopy of the known LCEs have been obtained. We find that Mrk 54 has a strong [C II] emission that accounts for $\sim1$% of the total FIR luminosity, whereas it has only moderate [O III] emission, resulting in the low [O III]/[C II] luminosity ratio of $0.22\pm0.06$. In order to investigate whether [O III]/[C II] is a useful tracer of $f_{\rm esc}$ (LyC escape fraction), we examine the correlations of [O III]/[C II] and (i) the optical line ratio of $\rm O_{32} \equiv$ [O III] 5007 Å/[O II] 3727 Å, (ii) specific star formation rate, (iii) [O III] 88 $μ$m/[O I] 63 $μ$m ratio, (iv) gas phase metallicity, and (v) dust temperature based on a combined sample of Mrk 54 and the literature data from the Herschel Dwarf Galaxy Survey and the LITTLE THINGS Survey. We find that galaxies with high [O III]/[C II] luminosity ratios could be the result of high ionization (traced by $\rm O_{32}$), bursty star formation, high ionized-to-neutral gas volume filling factors (traced by [O III] 88 $μ$m/[O I] 63 $μ$m), and low gas-phase metallicities, which is in agreement with theoretical predictions. We present an empirical relation between the [O III]/[C II] ratio and $f_{\rm esc}$ based on the combination of the [O III]/[C II] and $\rm O_{32}$ correlation, and the known relation between $\rm O_{32}$ and $f_{\rm esc}$. The relation implies that high-redshift galaxies with high [O III]/[C II] ratios revealed by ALMA may have $f_{\rm esc}\gtrsim0.1$, significantly contributing to the cosmic reionization.
description: 14 pages, 5 figures, Accepted for publication in ApJ
Evaluation of Funori as adhesive for stone polychromy. The XV century Ramon Llull’s sepulchre as Case Study
Creators: name: Rubio, Llucia Bosch
name: Cabezas, Manuel Jardón
name: Cortés, Marina Granero
name: Morelli, Philip Kron
Publisher: name: Estudos de Conservação e Restauro
Year: 2019

description: Adhesion and consolidation of pictorial layers has become one of the main challenges in conservation issues and, despite a growing availability of new resins and polymers, natural, traditional and well-known materials have been studied and improved, in order to face and solve modern issues. During the last conservation intervention on Ramon Llull’s sepulchre, the original polychromy has been rediscovered. A funori solution has been evaluated as the most suitable to undertake the intervention, and a specific methodology was developed in order to fix the layers. Funori’s reversibility and slight surfactant characteristics, allows that the removal of the grey overpaints could be easily carried out with wat
description: Estudos de Conservação e Restauro, n. 10 (2019): YOCOCU CONFERENCE 2019: 3rd International Conference of Green Conservation of Cultural Heritage
Spectral fit of Borexino Phase-III data for the detection of CNO solar neutrinos
Creators: name: Basilico, Davide
name: Settanta, Giulio
name: Bagdasarian, Zara
Publisher: name: Zenodo
Year: 2020

description: Borexino experiment, located at the Laboratori Nazionali del Gran Sasso, was built with a primary goal of the low-energy solar neutrino detection. In more than 12 years of data taking, Borexino has demonstrated the unprecedentedly high sensitivity towards solar neutrinos from the complete pp-chain, dominant process in the Sun fusion. After a number of developments in both hardware and software, Borexino is now ready to tackle the measurement of neutrinos produced in a subdominant Carbon-Nitrogen-Oxygen (CNO) cycle mechanism. One of the key steps of the analysis is the performance of spectral fit to disentangle neutrino signals from backgrounds in the detector. All the important aspects of the performed spectral fits are explained in the poster.
description: Video available on Youtube: https://youtu.be/kQN7ypVG9lk
Additional file 3 of Criteria for assessing the quality of clinical practice guidelines in paediatrics and neonatology: a mixed-method study
Creators: name: Joanna, Dagard
name: Nadia, Mazille-Orfanos
name: Nawras, Georgi
name: Intissar, Dechicha
name: Guy, Carrault
name: Patrick, Pladys
name: Alain, Beuchée
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Additional file 3. Consolidated database.
Can Physics Teaching be improved by Explanation of Tricks with a Motorcycle?
Creators: name: Risch, Matthias R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Physics Education (physics.ed-ph)
subject: Popular Physics (physics.pop-ph)
subject: FOS: Physical sciences
subject: PACS Codes 01.40.-d 01.80.+b 45.20.-d 45. 40.-f

description: A priority of physics instruction is to help students make the connection between the formulae they think they are required to memorize and the real world in which they interact every day. If you ask students to describe a situation in real life involving physical principles, the most commonly cited examples will pertain to vehicular motion. One situation in real life involving physical principles is vehicle dynamics. Even students who have little interest in physics eagerly discuss problems like how much a car can decelerate travelling in a flat turn or how tricks like the Wheely can be performed on a motorcycle. In the physics classroom, the motion of automotive vehicles is probably the most interesting manifestation of the principles of physics. The laws of physics limiting movements of vehicles are deduced here in a simple derivation suited for classroom demonstration as well as for homework. Due to limits on frictional forces there are subsequent limits for acceleration, deceleration and speed in a flat turn. Frictional forces also determine the behaviour of a vehicle at rapid speed in a turn.
description: 19 pages, 10 figures
Exploring the use of Acidithiobacillus Ferrooxidans for the removal of Sulphides from Tarnished Silver
Creators: name: Scheepers, Giel
name: Koster, Margot
name: Bennekom, Joosje Van
Publisher: name: Estudos de Conservação e Restauro
Year: 2019

description: Tarnished silver objects contain a black layer of silver sulfide. Current cleaning methods are not suitable for fragile objects, therefore, this exploratory study set out to develop a new biology-based method to clean silver. The extremophile bacterium Acidithiobacillus ferrooxidans was considered the most promising candidate, because of its ability to oxidize metal sulfides. The bacterium indirectly removed silver sulfide from tarnished silver coupons, through the generation of ferric iron. However, this procedure etched the silver. It was investigated whether A. ferrooxidans was able to directly oxidize silver sulfide in the absence of iron. However, no removal of silver sulfide was observed.
description: Estudos de Conservação e Restauro, n. 10 (2019): YOCOCU CONFERENCE 2019: 3rd International Conference of Green Conservation of Cultural Heritage
Constraints on the Binarity of the WN3/O3 Class of Wolf-Rayet Stars
Creators: name: Massey, Philip
name: Neugent, Kathryn F.
name: Morrell, Nidia I.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The WN3/O3 Wolf-Rayet (WR) stars were discovered as part of our survey for WRs in the Magellanic Clouds. The WN3/O3s show the emission lines of a high-excitation WN star and the absorption lines of a hot O-type star, but our prior work has shown that the absorption spectrum is intrinsic to the WR star. Their place in the evolution of massive stars remains unclear. Here we investigate the possibility that they are the products of binary evolution. Although these are not WN3+O3~V binaries, they could still harbor unseen companions. To address this possibility, we have conducted a multi-year radial velocity study of six of the nine known WN3/O3s. Our study finds no evidence of statistically significant radial velocity variations, and allows us to set stringent upper limits on the mass of any hypothetical companion star: for probable orbital inclinations, any companion with a period less than 100 days must have a mass less than 2Mo. For periods less than 10 days, any companion would have to have a mass less than 1Mo. We argue that scenarios where any such companion is a compact object are unlikely. The absorption lines indicate a normal projected rotational velocity, making it unlikely that these stars evolved with the aid of a companion star that has since merged. The modest rotation also suggests that these stars are not the result of homogenous evolution. Thus it is likely that these stars are a normal but short-lived stage in the evolution of massive stars.
description: Astrophysical Journal in press
L'attività di ricerca svolta dall'IZS Sardegna XI Convegno
Creators: name: IZS-Sardegna
Publisher: name: Zenodo
Year: 2020

description: L'evento si propone come momento di comunicazione agli operatori sanitari dei risultati della ricerca finanziata dal Ministero della Salute, condotta negli ultimi anni dall’IZS Sardegna. In particolare si evidenziano le ricadute per lo stato sanitario delle popolazioni animali, benessere animale e sicurezza degli alimenti. L'Istituto Zooprofilattico Sperimentale della Sardegna "G. Pegreffi" propone una panoramica delle ricerche svolte dall’Istituto negli ultimi anni. Si tratta del tradizionale appuntamento con i risultati conseguiti in alcune delle ricerche correnti concluse negli anni precedenti.
Generation and characterization of a novel mouse model of synovial sarcoma
Creators: name: Martin, Lauren Adria
Publisher: name: University of British Columbia
Year: 2024

description: Synovial sarcoma is an aggressive soft-tissue sarcoma that most frequently affects adolescents and young adults and can arise in virtually any area of the body. The biologic behaviour of synovial sarcoma can vary depending on several factors and the 10-year survival rate has been estimated at only 50%. Synovial sarcoma is characterized by a pathognomonic t(X;18)(p11.2;q11.2) translocation which produces a fusion oncogene named SS18-SSX. The cell of origin of synovial sarcoma is currently unknown, although recent research indicates that it may arise from a mesenchymal stem/progenitor cell population. We have generated a unique mouse model of synovial sarcoma where the human SS18-SSX fusion oncogene is conditionally expressed in a population of mesenchymal progenitor cells using a Hic1Cʳᵉᴱᴿᵀ² driver developed by our lab. This model shows robust formation of synovial sarcoma with 100% penetrance and a mean latency period of 16 weeks. The mouse tumours were characterized histologically, using immunofluorescence and hematoxylin and eosin staining, and at the transcriptomic level using single-cell RNA-sequencing. Histologic analysis reveals characteristic cellular morphology and marker expression, while scRNA-seq analyses show that gene expression in these tumours parallels transcript profiles observed in human synovial sarcoma samples. Using this model, we can identify and isolate early neoplastic lesions prior to the development of grossly visible tumours; scRNA-seq of early lesions shows a partially-transformed phenotype and highlights cellular programs involved early in sarcomagenesis. We then generated two modified versions of this model through the addition of stabilized β-catenin (Ctnnb1ᴱˣ³Fᴵ) and knockout of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (Smarcb1Fᴵ) to assess the effects of activated WNT/ β-catenin signaling and loss of Smarcb1, respectively. Both models show a decreased latency period and more aggressive phenotype and provide additional support for the roles of the WNT/ β-catenin pathway and chromatin remodeling complexes in synovial sarcomagenesis. Overall, these models identify Hic1+ mesenchymal progenitors as a putative cell of origin for synovial sarcoma and provide us with a unique opportunity to address the molecular and cellular mechanisms underlying synovial sarcomagenesis.