cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Airships: A New Horizon for Science
Creators: name: Miller, Sarah H.
name: Fesen, Robert
name: Hillenbrand, Lynne A.
name: Rhodes, Jason
name: Baird, Gil
name: Blake, Geoffrey A.
name: Booth, Jeff
name: Carlile, David E.
name: Duren, Riley
name: Edworthy, Frederick G.
name: Freeze, Brent
name: Friedl, Randall R.
name: Goldsmith, Paul F.
name: Hall, Jeffery L.
name: Hoffman, Scott E.
name: Hovarter, Scott E.
name: Jensen-Clem, Rebecca M.
name: Jones, Ross M.
name: Kauffmann, Jens
name: Kiessling, Alina
name: King, Oliver G.
name: Konidaris, Nick P.
name: Lachenmeier, Timothy L.
name: Lord, Steven D.
name: Neu, Jessica
name: Quetin, Gregory R.
name: Ram, Alan
name: Sander, Stanley
name: Simard, Marc
name: Smith, Mike
name: Smith, Steve
name: Smoot, Sara
name: Susca, Sara
name: Swann, Abigail
name: Young, Eliot F.
name: Zambrano, Thomas
Publisher: name: Keck Institute for Space Studies
Year: 2014

description: The "Airships: A New Horizon for Science" study at the Keck Institute for
Space Studies investigated the potential of a variety of airships currently
operable or under development to serve as observatories and science
instrumentation platforms for a range of space, atmospheric, and Earth science.
The participants represent a diverse cross-section of the aerospace sector,
NASA, and academia. Over the last two decades, there has been wide interest in
developing a high altitude, stratospheric lighter-than-air (LTA) airship that
could maneuver and remain in a desired geographic position (i.e.,
"station-keeping") for weeks, months or even years. Our study found
considerable scientific value in both low altitude (< 40 kft) and high altitude
(> 60 kft) airships across a wide spectrum of space, atmospheric, and Earth
science programs. Over the course of the study period, we identified
stratospheric tethered aerostats as a viable alternative to airships where
station-keeping was valued over maneuverability. By opening up the sky and
Earth's stratospheric horizon in affordable ways with long-term flexibility,
airships allow us to push technology and science forward in a project-rich
environment that complements existing space observatories as well as aircraft
and high-altitude balloon missions.
Closed Superstrings in a Uniform Magnetic Field and Regularization Criterion
Creators: name: Kokado, Akira
name: Konisi, Gaku
name: Saito, Takesi
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We summarize exact solutions of closed superstrings in a constant magnetic field, from a view point of the regularization criterion. Some models will be excluded according to this criterion. The spectrum-generating algebra is also constructed in these interacting models.
description: 13 pages, No figures
Behandlungsergebnisse von Keimzelltumoren des Hodens
Creators: name: Koppe, Simon Thomas
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 610 Medical sciences Medicine

description: In der vorliegenden Arbeit wurden die Risikofaktoren, Behandlungs- und Langzeitergebnisse von 265 Hodenkrebs-Patienten an der urologischen Klinik des Rostocker Universitätsklinikums über einen Zeitraum von 16 Jahren retrospektiv untersucht.
Distributions propres invariantes sur la paire sym\' etrique (gl(4,R),gl(2,R)*gl(2,R))
Creators: name: Harinck, Pascale
name: Jacquet, Nicolas
Publisher: name: arXiv
Year: 2011
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: We study orbital integrals and invariant eigendistributions for the symmetric pair (g,h)=(gl(4,R),gl(2,R)*gl(2,R)). Let q=g/h and let N be the set of nilpotents of q. We first obtain an asymptotic behavior of orbital integrals around nonzero semisimple elements of q. We study eigendistributions around such elements and give an explicit basis of eigendistributions on q-N given by a locally integrable function on q-N.
description: 79 pages, Submitted for publication
СОПОСТАВИТЕЛЬНЫЙ АНАЛИЗ АРАБСКИХ ЗАИМСТВОВАНИЙ КОНЦЕПТОСФЕРЫ «ЦВЕТ» В БРИТАНСКОМ И АМЕРИКАНСКОМ ВАРИАНТАХ АНГЛИЙСКОГО ЯЗЫКА
Creators: name: Сообщество рецензентов Международного научно-исследовательского журнала
Publisher: name: ООО Цифра
Year: 2023
Subjects: Arabic borrowings
lexical units
comparative analysis
colour denotations
English-language discourse
арабские заимствования
лексические единицы
сопоставительный анализ
цветовые обозначения
англоязычный дискурс

description: Russian Linguistic Bulletin, Выпуск 12 (48) 2023
Additional file 1 of Advantages of visualisations to evaluate and communicate adverse event information in randomised controlled trials
Creators: name: Cornelius, Victoria
name: Cro, Suzie
name: Phillips, Rachel
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1. Supplementary file
A MODIFIED SCHWARZ CRITERION FOR INCOMPLETE DATA
Creators: name: HASSANIA HAMZAOUI
name: ABDELAZIZ ALOUI
name: ABDELAZIZ EL MATOUAT
Publisher: name: Zenodo
Year: 2023
Subjects: Incomplete Data, Model Selection, Information Criteria, a Posterior Probability, Em Algorithm.

description: Abstract
It is well-known that the selection criteria make it possible to determine the order of a statistical model associated with the observed data. But in practice, the problem of missing values requires a modification of these criteria. For Akaike Information criterion, this problem of incomplete data was studied by Cavanaugh and Shumway (1998), they demonstrated an extension of Akaike's criterion to take account of missing values. But this criterion does not always lead to correct model selection. In this paper, we propose a new information criterion of Schwarz. This criterion is based on the motivation provided for the posterior probability of the candidate model and the EM algorithm. We have validated the theoretical results on simulated data. The new criterion converges to the correct order of the candidate model for both small and large samples, even if the percentage of missing data increases.
Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation
Creators: name: Guglielmi, Paolo
name: Rotondi, Giulia
name: Secci, Daniela
name: Angeli, Andrea
name: Chimenti, Paola
name: Nocentini, Alessio
name: Bonardi, Alessandro
name: Gratteri, Paola
name: Carradori, Simone
name: Supuran, Claudiu T.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: A large library of saccharin and acesulfame derivatives has been synthesised and evaluated against four isoforms of human carbonic anhydrase, the two off-targets hCA I/II and the tumour related isoforms hCA IX/XII. Different strategies of scaffold modification have been attempted on both saccharin as well as acesulfame core leading to the obtainment of 60 compounds. Some of them exhibited inhibitory activity in the nanomolar range, albeit some of the performed changes led to either micromolar activity or to its absence, against hCA IX/XII. Molecular modelling studies focused the attention on the binding mode of these compounds to the enzyme. The proposed inhibition mechanism is the anchoring to zinc-bound water molecule. Docking studies along with molecular dynamics also underlined the importance of the compounds flexibility (e.g. achieved through the insertion of methylene group) which favoured potent and selective hCA inhibition.
The mid-UV population of the nucleus and the bulk of the post-merger NGC 3610
Creators: name: Buson, Lucio
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The very center of NGC~3610, a clearly disturbed giant elliptical generally assumed to be a post-merger remnant, appears dominated in the mid-UV (2500-3200 A spectral region) by a stellar population markedly different from that dominating the bulk of its stellar body. I want here to make use of the mid-UV spectra of NGC~3610 as seen through tiny ($\sim$1") and large (10"$\times$20") apertures as a diagnostic population tool. I compare archive IUE/LWP large aperture and HST/FOS UV data of NGC 3610. The strength of mid-UV triplet (dominated by the turnoff population) shows a remarkable drop when switching from the galaxy central arcsec (FOS aperture) to an aperture size comparable to $\sim$0.5 r$_e$ (IUE). The sub-arsec (mid)-UV properties of this galaxy involved in a past merger reveal a central metal enrichment which left intact the bulk of its pre-existing population.
description: 6 pages, 2 figures, accepted for publication in astronomy and Astrophysics
Anatomische Beobachtungen zu ultraschallgestützten Regionalanästhesieverfahren in experimentellen Untersuchungen an Humanpräparaten sowie Prognosen zur Anpassung praxisnaher Methodiken zur Verbesserung des Patientenbenefits
Creators: name: Schulze, Marko
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 000 Generalities, Science
subject: 610 Medical sciences Medicine

description: Ziel der Arbeit war die Etablierung eines Modells zur Prüfung ultraschallgestützter regionalanästhesiologischer Techniken durch die Verwendung eines wässrigen Surrogats am Humanpräparat. Durch die Darstellung der sonographisch applizierten Farbstofflösungen sollten Rückschlüsse auf die klinische Wirksamkeit der Techniken durch die Imprägnierung der erreichten Strukturen geschlossen werden. Es sollten Nadelführung, Schallkopfposition, unterschiedliche Volumenapplikationen und der Vergleich zu Katheterverfahren als Mechanismen der Farbstoffverteilung in verschiedenen Ansätzen verglichen werden.
In-vitro Hepatotoxizitätsbestimmung intensivmedizinisch relevanter Hypnotika und Opioide mit der permanenten humanen Hepatozytenzelllinie Hep G2/C3A
Creators: name: Haller, Katharina Anna
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 500 Natural sciences
subject: 610 Medical sciences Medicine

description: Unter Verwendung der permanenten Hepatomzelllinie HepG2/C3AEs wurden intensivmedizinisch genutzte Sedativa, Hypnotika und Opioide auf Hepatotoxizität untersucht. Die Beurteilung der Zytotoxizität erfolgte durch lichtmikroskopische Bestimmung von Zellzahl und Vitalität, Messung der freigesetzten Laktatdehydrogenase, fluorometrische Bestimmung der Aktivität mitochondrialer Dehydrogenasen im XTT-Test sowie Syntheseleistung anhand der Mikroalbuminkonzentration. Weiterhin wurde die Aktivität des CYP1A2-Enzyms bestimmt, um Einflüsse auf die Metabolisierungsleistung zu untersuchen.
Digging Deeper: Algorithms for Computationally-Limited Searches in Astronomy
Creators: name: Djorgovski, S. G.
name: Cutler, Curt
name: Elmegreen, Bruce G.
name: Vallisneri, M.
name: Mahabal, A.
Publisher: name: Keck Institute for Space Studies
Year: 2012

description: Astronomy, like most other fields, is being deluged by exponentially growing streams of ever more complex data. While these massive data streams bring a great discovery potential, their full scientific exploitation poses many challenges, due to both data volumes and data complexity.
Moreover, the need to discover and characterize interesting, faint signals in such data streams quickly and robustly, in order to deploy costly follow-up resources that are often necessary for
the full scientific returns, makes the challenges even sharper. Examples in astronomy include transient events and variable sources found in digital synoptic sky surveys, gravitational wave signals, faint radio transients, pulsars, and other types of variable sources in the next generation of panoramic radio surveys, etc. Similar situations arise in the context of space science and planetary exploration, environmental monitoring, security, etc. In most cases, rapid discovery
and characterization of interesting signals is highly computationally limited. The goal of this study was to define a number of interesting, often mission-critical challenges of this nature in the
broader context of time-domain astronomy, but with an eye on their applicability elsewhere.
Lifting the Veil on Obscured Accretion: Active Galactic Nuclei Number Counts and Survey Strategies for Imaging Hard X-ray Missions
Creators: name: Ballantyne, D. R.
name: Draper, A. R.
name: Madsen, K. K.
name: Rigby, J. R.
name: Treister, E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Finding and characterizing the population of active galactic nuclei (AGNs) that produces the X-ray background (XRB) is necessary to connect the history of accretion to observations of galaxy evolution at longer wavelengths. The year 2012 will see the deployment of the first hard X-ray imaging telescope that, through deep extragalactic surveys, will be able to measure the AGN population at the energies where the XRB peaks (~20-30 keV). Here, we present predictions of AGN number counts in three hard X-ray bandpasses: 6-10 keV, 10-30 keV and 30-60 keV. Separate predictions are presented for the number counts of Compton thick AGNs, the most heavily obscured active galaxies. The number counts are calculated for five different models of the XRB that differ in the assumed hard X-ray luminosity function, the evolution of the Compton thick AGNs, and the underlying AGN spectral model. The majority of the hard X-ray number counts will be Compton thin AGNs, but there is a >10x increase in the Compton thick number counts from the 6-10 keV to the 10-30 keV band. The Compton thick population show enough variation that a hard X-ray number counts measurement will constrain the models. The computed number counts are used to consider various survey strategies for the NuSTAR mission, assuming a total exposure time of 6.2 Ms. We find that multiple surveys will allow a measurement of Compton thick evolution. The predictions presented here should be useful for all future imaging hard X-ray missions.
description: 43 pages, 10 figures, accepted by the ApJ
Gas fractionation and CO2-dynamics in natural high-CO2-systems
Creators: name: Beilfuhs, Stine
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 500 Natural sciences
subject: 540 Chemistry & allied sciences

description: The Okinawa Trough is a natural hydrothermal gas emission field. The flux of CO2 into the water column is dominated by hot hydrothermal CO2-rich vents. The influence of the emitted low-temperatured gas bubbles and droplets (‘condensed phase’) is very likely restricted to the lowermost part of the water column. Despite their proximity the gas composition of the condensed phases varies widely, especially in methane, which is likely caused by diverse phase transformation and thus fractionation below and above the seafloor.
Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors
Creators: name: Sardaru, Monica-Cornelia
name: Craciun, Anda Mihaela
name: Matarneh, Cristina-Maria Al
name: Sandu, Isabela Andreea
name: Amarandi, Roxana Maria
name: Popovici, Lacramioara
name: Ciobanu, Catalina Ionica
name: Peptanariu, Dragos
name: Pinteala, Mariana
name: Mangalagiu, Ionel I.
name: Danac, Ramona
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: A potential microtubule destabilising series of new indolizine derivatives was synthesised and tested for their anticancer activity against a panel of 60 human cancer cell lines. Compounds 11a, 11b, 15a, and 15j showed a broad spectrum of growth inhibitory activity against cancer cell lines representing leukaemia, melanoma and cancer of lung, colon, central nervous system, ovary, kidney, breast, and prostate. Among them, compound 11a was distinguishable by its excellent cytostatic activity, showing GI50 values in the range of 10–100 nM on 43 cell lines. The less potent compounds 15a and 15j in terms of GI50 values showed a high cytotoxic effect against tested colon cancer, CNS cancer, renal cancer and melanoma cell lines and only on few cell lines from other types of cancer. In vitro assaying revealed tubulin polymerisation inhibition by all active compounds. Molecular docking showed good complementarity of active compounds with the colchicine binding site of tubulin.
Dehydrierung von 1-Buten zu 1,3-Butadien in Gegenwart von Kohlendioxid
Creators: name: Iffländer, Karl Friedrich
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 540 Chemistry & allied sciences

description: Verschiedene Vanadiumoxid-Katalysatoren (VOx/SBA-15) wurden hergestellt, charakterisiert und in der Dehydrierung von 1-Buten zu Butadien in Gegenwart von CO2 getestet. Fein verteilte, hohe VOx-Beladungen sind verbunden mit einer hohen Butadien-Produktion und einer starken Koksbildung. Die Butadien-Produktion an VOx/SBA-15 war in CO2 höher als in Inertgas. Ferner wurden drei Eisenkatalysatoren untersucht. In CO2 war die Butadien-Produktion an zwei Katalysatoren geringer als in Inertgas. Die Adsorption von Wassermolekülen an der Katalysatoroberfläche könnte ein Grund für diese Beobachtung sein.
Designing an accessible group yoga class for adults with aphasia post-stroke. Phase one : qualitative interviews
Creators: name: Ross, Kelsea Michelle
Publisher: name: University of British Columbia
Year: 2018

description: Background: Yoga is a community-based activity with great potential psychosocial and physical benefit to stroke survivors, one in three of whom has chronic aphasia. People with aphasia post-stroke may be unable to experience the benefits of yoga due to unique environmental factors that impact their participation; therefore, yoga classes need to be made more accessible for these individuals. Aim: The aim of this study was to explore barriers and facilitators to participation in a group yoga class for people with aphasia post-stroke from the perspective of people with aphasia, allied health professionals, and yoga instructors. Methods and Procedures: This study, underpinned by the critical paradigm, was the first phase of a participatory action research (PAR) project. Semi-structured qualitative interviews were conducted with 4 people with aphasia, 4 allied health professionals, and 4 yoga instructors. All participants had knowledge or experience with both aphasia and yoga. Interviews were transcribed and analyzed using qualitative content analysis. Member checking and peer debriefing were used to enhance rigour. Results: Analysis of participant interviews revealed 44 barriers grouped into 11 categories and 56 facilitators grouped into 11 categories. Barrier categories included: lack of collaboration with key stakeholders; lack of aphasia awareness in the yoga facility; advertising strategies are not aphasia-friendly; lack of participatory support from yoga provider and social network; yoga instructor does not have the necessary knowledge, skills, and attitudes; class composition and structure is not aphasia-friendly; and complex communication requirements. Facilitator categories included: collaboration with key stakeholders; aphasia education in the yoga facility; aphasia-friendly advertising strategies; additional participatory support from yoga provider and social network; yoga instructor has the necessary knowledge, skills, and attitudes; aphasia-friendly class composition and structure; and supported communication in the yoga facility. Conclusion: Results may guide the development of a communicatively accessible group yoga class for people with aphasia-post stroke in the future. Collaboration between the yoga provider and the specific group of yoga students with aphasia may be integral to class success and longevity. Further research investigating the validity of study results in a real-life context is indicated.
Entwicklung spektraler Messmethoden für Doppler-Lidar
Creators: name: Froh, Jan
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 530 Physics

description: Zur Untersuchung der mittleren Atmosphäre (10-100 km) wurde in dieser Arbeit ein kompaktes transportables Doppler-Lidar (≈ 1 m^3) mit Tageslichtfähigkeit entwickelt und anhand erster Atmosphärenmessungen bestätigt. Mit hoher zeitlicher, räumlicher sowie spektraler Auflösung werden ganze Doppler-Spektren der Mie- und Rayleigh-Streuung sowie der Kalium-Resonanzfluoreszenz untersucht, was genaue Wind-, Temperatur- sowie Aerosolmessungen ermöglicht. Das System wurde als Netzwerklidar entwickelt und wird zukünftig als Verbund mehrerer solcher Geräte die Atmosphäre mehrdimensional untersuchen.
Additional file 1 of Remote sensing of fish-processing in the Sundarbans Reserve Forest, Bangladesh: an insight into the modern slavery-environment nexus in the coastal fringe
Creators: name: Jackson, Bethany
name: Boyd, Doreen S.
name: Ives, Christopher D.
name: Sparks, Jessica L. Decker
name: Foody, Giles M.
name: Marsh, Stuart
name: Bales, Kevin
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: (DOCX 29.2 kb)
Toward the nonmetal-to-metal phase transition of helium
Creators: name: Preising, Martin
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 000 Generalities, Science
subject: 500 Natural sciences
subject: 530 Physics

description: Properties of helium under high pressure are of great importance for a variety of astrophysical objects. This work presents results of extensive ab initio calculations for high-pressure helium regarding the equation of state, the melting line, the electrical conductivity, the reflectivity, and the band gap. The calculations determined a higher-order phase transition from an insulating to a conducting phase which has been discussed for decades. This work finally proposes an update of the phase diagram of helium and discusses its implications on dwarf stars and giant planets.
Percussive Scoop Sampling in Extreme Terrain
Creators: name: Hassenruck-Gudipati, Hima
Publisher: name: Keck Institute for Space Studies
Year: 2016

description: Axel is a minimalistic cliff climbing rover that can explore
extreme terrains from the moon, Mars, and beyond. To
increase the technology readiness and scientific usability
of Axel, a sampling system needs to be designed and
build for sampling different rock and soils. To decrease
the amount of force required to sample clumpy and
possibly icy science targets, a percussive scoop could be
used. A percussive scoop uses repeated impact force to
dig into samples and a rotary actuation to collect the
samples. Percussive scooping can reduce the amount of downward force required by about two to four
times depending on the cohesion of the soil and the depth of the sampling. The goal for this project is to
build a working prototype of a percussive scoop for Axel.
Pneumatic Sampling in Extreme Terrain with the Axel Rover
Creators: name: Huang, Yifei
Publisher: name: Keck Institute for Space Studies
Year: 2012

description: Some of the most interesting regions of study in our solar system lie inside craters, canyons, and
cryovolcanoes, but current state-of-the-art rovers are incapable of accessing and traversing these
regions. Axel is a minimalistic rover designed for extreme terrains, and two Axels with a central mother
system form a four-wheeled rover to efficiently traverse flat ground. Upon approaching the edge of a
crater, Axel detaches from the mother system and travels down the cliff guided by the unwinding tether.
However, scientific study of extraplanetary terrains requires instrumentation inside the Axel rover. We
aim to develop a simple and reliable sample acquisition and caching system that could retrieve multiple
samples from various sites before returning them to the mother system where more sophisticated
instruments could perform further analysis. For simplicity and robustness, we propose a pneumatic
sampling system which uses compressed air, guided with a nozzle, to blow soil into a sample canister.
Numerous types of nozzles were designed, built, and tested. Different designs for nozzle deployment,
sample caching, and pressure containment were considered. Finally, a prototype of the entire sampling
system was built and evaluated for performance and feasibility.
Study of Transient Nuclei near Freezing
Creators: name: Isobe, Masaharu
name: Alder, Berni J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The molasses tail in dense hard core fluids is investigated by extensive event-driven molecular dynamics simulation through the orientational autocorrelation functions. Near the fluid-solid phase transition, there exist three regimes in the relaxation of the pair orientational autocorrelation function, namely the kinetic, molasses (stretched exponential), and diffusional power decay. The density dependence of both the molasses and diffusional power regimes are evaluated and the latter compares with theoretical predictions in three dimensions. The largest cluster at the freezing density of only a few sphere diameter in size persist for only about 30 picoseconds (~ 2.8 x 10^{-11}[s]). The most striking observation through the bond orientatinal order parameter is the dramatic increase of the cluster size as the freezing density is approached.
description: 12 pages, 8 figures, 3 tables, To appear in the Proceedings of YKIS2009 Frontiers in Nonequilibrium Physics, Progress of Theoretical Physics Supplement (2010).
30 kV coaxial vacuum-tight feedthrough for operation at cryogenic temperatures
Creators: name: Kreslo, I.
name: Badhrees, I.
name: Delaquis, S.
name: Ereditato, A.
name: Janos, S.
name: Messina, M.
name: Moser, U.
name: Rossi, B.
name: Zeller, M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: In this paper we describe the technology of building a vacuum-tight high voltage feedthrough which is able to operate at voltages up to 30 kV. The feedthrough has a coaxial structure with a grounded sheath which makes it capable to lead high voltage potentials into cryogenic liquids, without risk of surface discharges in the gas phase above the liquid level. The feedthrough is designed to be used in ionization detectors, based on liquefied noble gases, such as Argon or Xenon.
IT-gestützte Arbeitszeiterfassung bei Gymnasiallehrkräften aus Mecklenburg-Vorpommern
Creators: name: Felsing, Christoph J.
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 610 Medical sciences Medicine

description: In der vorliegenden Dissertation sollen erstmals für Gymnasiallehrkräfte in Mecklenburg-Vorpommern die Wochenarbeitszeit und ihre Teiltätigkeiten im Methodenvergleich von Schätzung und Protokollierung ermittelt (LaiW-Studie I) sowie die Verteilung der Arbeitszeit im Tages- und Wochenverlauf mit einer neu entwickelten Arbeitszeit-App (LaiW-App) untersucht werden (LaiW-Studie II). Dadurch lassen sich weiterführende Aussagen zur Methodik der Arbeitszeiterfassung und zu den tatsächlichen Arbeits- und Erholungsphasen dieser Berufsgruppe ableiten.
Additional file 1 of Presence of salivary IgA anti-citrullinated protein antibodies associate with higher disease activity in patients with rheumatoid arthritis
Creators: name: Ljungberg, Karin Roos
name: Börjesson, Emil
name: Martinsson, Klara
name: Wetterö, Jonas
name: Kastbom, Alf
name: Svärd, Anna
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1 : Supplementary Table 1. Radiographic joint erosions versus ACPA isotypes. Abbreviations: ACPA anti-cyclic citrullinated peptides, SC secretory component containing.
Minimax estimation of the mode of functional data
Creators: name: Müller, Dennis
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 510 Mathematics

description: Wir untersuchen den Modalwert einer Verteilung, die auf einem Funktionenraum wie etwa dem Raum integrierbarer Funktionen definiert ist. Die Definition des Modalwerts basiert auf Small-Ball-Wahrscheinlichkeiten. Wir benutzen Entropiemethoden wie etwa endliche Überdeckungen für die Definition eines Modalwertschätzers und die Beschreibung seines asymptotischen Verhaltens. Wir zeigen die starke Konsistenz und ermitteln die optimale Konvergenzrate für eine Klasse von Verteilungen, deren Modalwerte in einer totalbeschränkten Teilmenge des Funktionenraums liegen.
Hard X-ray Emission from the NGC 5044 Group
Creators: name: Henriksen, Mark J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Observations made with the Rossi X-ray Timing Explorer (RXTE) Proportional Counter Array (PCA) to constrain the hard X-ray emission in the NGC 5044 group are reported here. Modeling a combined PCA and ROSAT position sensitive proportional counter (PSPC) spectrum with a 0.5 - 15 keV energy range shows excess hard emission above 4 keV. Addition of a powerlaw component with spectral index of 2.6 - 2.8 and luminosity of 2.6 x10^42 ergs/s within 700 kpc in the observed energy band removes these residuals. Thus, there is a detection of a significant non-thermal component that is 32% of the total X-ray emission. Point source emission makes up at most 14% of the non-thermal emission from the NGC 5044 group. Therefore, the diffuse, point source subtracted, non-thermal component is 2.2 - 3.0x10^42 ergs/s . The cosmic-ray electron energy density is 3.6 x10^[-12] ergs cm-3 and the average magnetic field is 0.034 \muGauss in the largest radio emitting region. The ratio of cosmic-ray electron energy density to magnetic field energy density, ~2.5x10^4, is significantly out of equipartition and is therefore atypical of radio lobes. In addition, the group's small size and low non-thermal energy density strongly contradicts the size-energy relationship found for radio lobes. Thus, it is unlikely to the related to the active galaxy and is most likely a relic of the merger. The energy in cosmic-rays and magnetic field is consistent with simulations of cosmic-ray acceleration by merger shocks.
description: 17 pages, including 4 figures and 2 tables
title: Vorgehensweise zur simulationsbasierten Entwicklung eines kognitiven Assistenzsystems für Marineschiffe
Creators: name: Özyurt, Emre
name: Döring, Bernhard
name: Flemisch, Frank
Publisher: name: DuEPublico: Duisburg-Essen Publications Online, University of Duisburg-Essen, Germany
Year: 2013

description: Die zunehmende Komplexität soziotechnischer Systeme erfordert es, intelligente Assistenzsysteme zu entwickeln, die die menschlichen Systemkomponenten innerhalb eines Mensch-Maschine-Systems bei der Aufgabendurchführung unterstützen. Bei den modernen Einsatzsystemen auf Deutschen Marineschiffen handelt es sich um komplexe soziotechnische Systeme, die aufgrund der weltweiten Sicherheitslagen ein vielfältiges Einsatzspektrum erfüllen müssen. Diese Einsatzsysteme umfassen leistungsstarke Sensoren, Kommunikationsanlagen und Effektoren und sollen gewährleisten, dass die Besatzung kritische Aufgaben angemessen bewältigen kann. Diese Aufgaben sind durch Informationsunsicherheit, eine dynamische Einsatzumgebung, variierende und konkurrierende Zielsetzungen, Zeitdruck sowie ein hohes Entscheidungsrisiko gekennzeichnet. Da das vorhandene Personal eines technischen militärischen Systems künftig mit zunehmend komplexen und unvorhersehbaren Szenarien konfrontiert werden wird und auch die eingesetzten technischen Systemanteile zunehmend komplexer werden, ist im Einsatz eine Entlastung des Personals bei der erforderlichen Aufgabenbewältigung durch neuartige technische Möglichkeiten wie z.B. kognitive Assistenzsysteme unumgänglich. In diesem Beitrag wird die Vorgehensweise bei der simulationsbasierten Entwicklung eines Kognitiven Assistenzsystems beschrieben. Gegenstand der Betrachtungen ist ein Unterstützungssystem für die Identifizierung von Luftzielen auf Marineschiffen. Seine Struktur und seine Funktionalität werden detailliert erläutert.
Evaluating the impact of a healing garden on adults in custody at Oregon State Penitentiary
Creators: name: Charney, Thomas
Publisher: name: My University
Year: 2023
Subjects: Environmental Psychology
Landscape Architecture
Transformative Justice

description: There is an established and ever-growing body of literature that supports the use of green space for both treating and preventing illnesses both physical and psychological for the general public. An arm of this research has suggested that green space can also help to normalize carceral environments and make them more conducive to addressing the trauma of Adults in Custody (AIC) and reducing recidivism rates. However, more research is necessary for many stakeholders in the department of corrections to invest in green space for AIC. Thus, existing projects such as the Memorial Healing Garden (MHG) at the Oregon State Penitentiary (OSP) provide valuable opportunities to investigate potential impacts and gain insight into how green spaces could be incorporated into carceral settings and accordingly make informed decisions. Through this study, I seek to increase our understanding of the garden’s impact from several angles: To what extent does the MHG benefit the well-being of AIC? Does the MHG have a distinguishably different effect on well-being than other outdoor spaces at OSP? What elements or garden features are most supportive of the well-being of incarcerated individuals? These questions were explored through Likert scale surveys with text and photo prompts related to the MHG that were distributed to AIC. Factor analysis of survey responses was then employed to determine overall trends. Findings reveal that the MHG has a distinguishably positive effect on AIC well-being and even more so among acutely stressed individuals. Water features and culturally inspired elements were the most endorsed aspect of the garden. These findings advocate for the inclusion of high quality green space in prisons and to reconsider operations to maximize its use in daily operations. Through their skill set for making impactful green spaces, landscape architects and designers should take this opportunity to expand the profession’s positive impact on society.
Computational Insights into Ion Mobility Spectrometry and Electrospray Ionization
Creators: name: Hillen, Robin
Publisher: name: Bergische Universität Wuppertal
Year: 2023

description: The topic of the work is the description of the ion dynamics within ion mobility devices as well as electrospray ion sources under different conditions. Depending on the question, various properties of the ions are determined as precisely as possible, e.g. their kinetic energy or reduced ion mobility. For this purpose, the pressure and flow profiles of the background gas are first determined and then used as input parameters for subsequent ion dynamics simulations. To model the neutral gas flow properties, either the continuum model or the Direct Simulation Monte Carlo (DSMC) approach are used. This is represented by the two programs OpenFOAM and SPARTA. For the ion trajectory calculations, SIMION is mostly used, in addition to a customized SPARTA version of the SPARTA framework. Overall, this work consists of three parts:In the first part, a new method for the calculation of reduced ion mobilities and therefore drift velocities in a high-kinetic energy ion mobility spectrometer (HiKE-IMS) is presented. The main feature of this method is that within one simulation run, not only the ions and background gas particles and their interactions are calculated simultaneously, but also simulation parameters as the electric field can be adjusted during runtime.The next part describes a method for determining the effect of a specific ion transfer system on the transferred ions. In this context, a two- and three-dimensional models are compared with each other with regard to the neutral gas flow properties.The third part presents an approach for determining the size distribution of droplets, which are formed within the electrospray ionization (ESI) process, in dependence of the induced ESI current. The simulations presented suggest that it is possible to detect droplets with approximately 10000 charges. In addition, an evaporation model is successfully integrated into an existing collision model, to obtain more comprehensive results.
Investigating the mammalian heat-shock induced ubiquitination response
Creators: name: Rose, Amalia
Publisher: name: University of British Columbia
Year: 2018

description: Aggregation of misfolded proteins in the cell is often indicative of a failing protein quality control system, whose responsibility is to mediate either the refolding or degradation of these aberrant proteins. Heat-shock (HS), which causes proteins to misfold, leads to a marked increase of the ubiquitination of proteins that display poor solubility in the cell. The E3 ubiquitin ligase Rsp5 has previously been shown to be the major ubiquitin ligase that targets cytosolic misfolded proteins upon HS in S. cerevisiae. Its closest mammalian orthologue, Nedd4-1, was also found to be responsible for an increased ubiquitination upon HS in HeLa and MEF cells, however further work is needed to better characterize this response. Such characterization included looking at which proteins get ubiquitinated upon HS to then determine whether they share common characteristics such as cellular localization, and if they are newly synthesized versus pre-existing. Using diGly enrichment coupled with mass spectrometry, we identified over 300 proteins that were further ubiquitinated upon HS. An important portion of these proteins are localized in the nucleus, whereas proteins associated to the mitochondria are markedly under-represented. As well, proteins involved in processes such as pre-mRNA processing, cell cycle and SUMOylation were found to be enriched. Using a pulse-SILAC approach, we found that a large portion of proteins ubiquitinated after HS were pre-existing, whereas some were newly synthesized including ribosomal proteins. We also investigated the potential role of other Nedd4 family members in the HS ubiquitination response in Hek293 cells. Using shRNA, we found that the knockdown of the Itch E3, but not of Nedd4-1, caused a decrease of the HS-induced ubiquitination response in these cells. Accordingly, we also showed a reduced cell viability upon Itch knocked down under HS.
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX
Creators: name: Kugler, Michael
name: Holub, Josef
name: Brynda, Jiří
name: Pospíšilová, Klára
name: Anwar, Suzan El
name: Bavol, Dmytro
name: Havránek, Miroslav
name: Král, Vlastimil
name: Fábry, Milan
name: Grüner, Bohumír
name: Řezáčová, Pavlína
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 60506 Virology

description: Human carbonic anhydrase IX (CA IX), a protein specifically expressed on the surface of solid tumour cells, represents a validated target both for anticancer therapy and diagnostics. We recently identified sulfonamide dicarbaboranes as promising inhibitors of CA IX with favourable activities both in vitro and in vivo. To explain their selectivity and potency, we performed detailed X-ray structural analysis of their interactions within the active sites of CA IX and CA II. Series of compounds bearing various aliphatic linkers between the dicarbaborane cluster and sulfonamide group were examined. Preferential binding towards the hydrophobic part of the active site cavity was observed. Selectivity towards CA IX lies in the shape complementarity of the dicarbaborane cluster with a specific CA IX hydrophobic patch containing V131 residue. The bulky side chain of F131 residue in CA II alters the shape of the catalytic cavity, disrupting favourable interactions of the spherical dicarbaborane cluster.
Dealing with highly polluted stormwater-runoff from silo facilities
Umgang mit stark verschmutztem Niederschlagswasser aus Siloanlagen
Creators: name: Cramer, Michael
Publisher: name: Universität Rostock, Agrar- und Umweltwissenschaftliche Fakultät, Professur Wasserwirtschaft
Year: 2021
Subjects: subject: 620 Engineering & allied operations
subject: 624 Structural and Environmental Engineering
subject: 660 Chemical engineering

description: Due to the raw materials stored on site, stormwater from silo facilities has a high organic and nutrient load that must be treated before discharge to surface or groundwater. Due to the entirely different composition of this wastewater compared to urban runoff, completely new evaluation criteria and treatment systems must be developed for this. The aim of the research project was to define the technical basis for the treatment of stormwater runoff and offer a reliable stormwater treatment process.
A gallery of bubbles - The nature of the bubbles observed by Spitzer and what ATLASGAL tells us about the surrounding neutral material
Creators: name: Deharveng, L.
name: Schuller, F.
name: Anderson, L. D.
name: Zavagno, A.
name: Wyrowski, F.
name: Menten, K. M.
name: Bronfman, L.
name: Testi, L.
name: Walmsley, C. M.
name: Wienen, M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We attempt to determine the nature of the bubbles observed by Spitzer in the Galactic plane, mainly to establish if possible their association with massive stars. We take advantage of the very simple morphology of these objects to search for star formation triggered by HII regions, and to estimate the importance of this mode of star formation. We consider a sample of 102 bubbles detected by Spitzer-GLIMPSE, and catalogued by Churchwell et al.(2006). We use mid-infrared and radio-continuum public data to discuss their nature. We use the ATLASGAL survey at 870 micron to search for dense neutral material collected on their borders. Results: We find that 86% of the bubbles contain ionized gas detected by means of its radio-continuum emission at 20-cm. Thus, most of the bubbles observed at 8.0 micron enclose HII regions ionized by O-B2 stars. Ninety-eight percent of the bubbles exhibit 24 micron emission in their central regions. The ionized regions at the center of the 8.0 micron bubbles seem to be devoid of PAHs but contain hot dust. Among the 65 regions for which the angular resolution of the observations is high enough to resolve the spatial distribution of cold dust at 870 micron, we find that 40% are surrounded by cold dust, and that another 28% contain interacting condensations. The former are good candidates for the collect and collapse process, as they display an accumulation of dense material at their borders. The latter are good candidates for the compression of pre-existing condensations by the ionized gas. Eighteen bubbles exhibit associated ultracompact HII regions and/or methanol masers in the direction of dust condensations adjacent to their ionization fronts. Our results suggest that more than a quarter of the bubbles may have triggered the formation of massive objects.
description: 36 pages, 27 figures, 500 figures online at http://lamwws.oamp.fr/bubbles. Paper accepted by A&A
Modeling of blood flow in the framework of micropolar theory
Creators: name: Vilchevskaya, Anastasiya E.
name: Vilchevskaya, Elena N.
name: Müller, Wolfgang H.
name: Eremeyev, Victor A.
Publisher: name: Springer Science and Business Media LLC
Year: 2023
Subjects: subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik
subject: micropolar media
subject: blood flow
subject: microstructural change
subject: microinertia with production

description: In this paper, we study the blood flow through blood vessels of various radii (including the case of variable cross section as well as modeling the blood flow through venae and arteries). Two approaches are discussed in order to mimic the dependence of blood viscosity on red blood cells aggregation, which changes with the shear rate and position inside the vessel: Two microstructural parameters together with empirical constitutive equations as a characteristic of aggregation are proposed, namely the microinertia as well as the volume fraction of blood particles (erythrocytes, platelets and leukocytes). Consequently, the Navier–Stokes system of equations for an incompressible fluid is supplemented by a constitutive equation for the moment of inertia in one case and for the volume fraction in another. The problems are solved numerically by the finite volume method for vessels of various geometries in spatial description. A comparison with experimental data for a narrow capillary shows the efficiency of the proposed constitutive equations for describing blood flow. Also, velocity profiles are obtained on the basis of compiled empirical formula for various sections of a blood vessel of variable radius. In addition, the flow through vessels of the human circulatory system, such as the inferior vena cava and the carotid artery, are studied.
Optical tweezers: wideband microrheology
Creators: name: Preece, Daryl
name: Warren, Rebecca
name: Tassieri, Manlio
name: Evans, R. M. L.
name: Gibson, Graham M.
name: Padgett, Miles J.
name: Cooper, Jonathan M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Microrheology is a branch of rheology having the same principles as conventional bulk rheology, but working on micron length scales and micro-litre volumes. Optical tweezers have been successfully used with Newtonian fluids for rheological purposes such as determining fluid viscosity. Conversely, when optical tweezers are used to measure the viscoelastic properties of complex fluids the results are either limited to the material's high-frequency response, discarding important information related to the low-frequency behavior, or they are supplemented by low-frequency measurements performed with different techniques, often without presenting an overlapping region of clear agreement between the sets of results. We present a simple experimental procedure to perform microrheological measurements over the widest frequency range possible with optical tweezers. A generalised Langevin equation is used to relate the frequency-dependent moduli of the complex fluid to the time-dependent trajectory of a probe particle as it flips between two optical traps that alternately switch on and off.
description: 13 pages, 6 figures, submitted to Special Issue of the Journal of Optics