cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Heavy elements in old very metal-rich stars
Creators: name: Trevisan, M.
name: Barbuy, B.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We studied a sample of high proper motion, old and metal-rich dwarf stars, selected from the NLTT catalogue. The low pericentric distances and eccentric orbits of these solar neighbourhood stars indicate that they might have originated in the inner parts of the Galaxy. Chemical tagging can probe the formation history of stellar populations. To identify the origin of a sample of 71 very metal-rich dwarf stars, we derive the abundances of the neutron-capture elements Y, Ba, La, and Eu. The spectroscopic analysis is based on optical high-resolution echelle spectra obtained with the FEROS spectrograph at the ESO 1.52-m Telescope at La Silla, Chile. The abundances of Y, Ba, La, and Eu were derived through LTE analysis, employing the MARCS model atmospheres. The abundances of Y, Ba, La, and Eu vs. Fe and Mg as the reference elements indicate similarities between our sample of old metal-rich dwarf stars and the thin disk. On the other hand, the abundance ratios using O as the reference element, as well as their kinematics, suggest that our sample is clearly distinct from the thin-disk stars. They could be old inner thin-disk stars, as suggested previously, or bulge stars. In either cases they would have migrated from the inner parts of the Galaxy to the solar neighbourhood.
description: 16 pages, to appear in A&A
An Examination of Formal, Non-formal, and Informal Environmental Stewardship Education in Tuvalu
Creators: name: Saosaoa Tinilau, Soseala
Publisher: name: University of Lincoln
Year: 2024
Subjects: X900 - Others in education
L217 - Environmentalism

description: In the Anthropocene, humans’ desire to improve their living standards has significantly threatened nature and its finite resources, prompting an urgent call to mitigate climate change and address environmental degradation. This urgency is especially important in a vulnerable country like Tuvalu, where people passionately advocate for saving it from destruction and where the concept of responsibility to future and current generations is pressing. Thorne defined environmental stewardship (ES) as “action that restores and maintains the integrity of a healthy Earth System (2017, v).” She insists that by developing ES, people are better equipped to respond to current environmental challenges, and this concept must be taught in schools to improve well-being. Despite the recognised importance of education in fostering societal and environmental well-being, there is a significant gap in integrating environmental stewardship education (ESE) within Tuvalu’s formal education systems.
This PhD research examines how formal, non-formal, and informal education contributes to ES, assessing their impact on the Tuvaluan community’s knowledge, skills, attitudes, and behaviours. A mixed-methods research design was adopted, utilising an explanatory sequential, concurrent approach that involves two data collection phases. In the first phase, an analysis of documentary data consisting of Tuvalu Government education policy documents, frameworks, reports and curricula specific to ES, sustainability, the environment, biodiversity, climate change, and disaster risk reduction were reviewed. In the second phase, quantitative and qualitative data were collected simultaneously using surveys, interviews, and focus groups from a variety of institutional and community groups of respondents: 389 elementary and high school students, 19 teachers, and 29 holders and recipients of Traditional Ecological Knowledge (TEK) from the Funafuti, Vaitupu, and Nukulaelae communities.
Self-Consistent Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C via Controlled Oligomerization
Creators: name: Schmitt, Daniel C.
name: Nicewicz, David A.
name: Johnson, Jeffrey S.
name: Satterfield, Andrew D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Despite the prevalence of repeating subunits in chiral natural products, stereocontrolled oligomerization is a largely unexplored strategy for construction of carbon skeletal frameworks. This report describes the use of silyl glyoxylates as dipolar glycolic acid synthons in a controlled oligomerization reaction for the efficient construction of the squalene synthase inhibitor zaragozic acid C. This new methodology allows rapid, stereocontrolled formation of the carbon skeleton with a desirable protecting group scheme while minimizing functional group repair and oxidation state manipulations.
BINARY LOGISTIC REGRESSION ANALYSIS FOR THE RELATIONSHIP OF AN UNDERGRADUATE STUDY CHOICE AT PHIBUNSONGKHRAM RAJABHAT UNIVERSITY WITH VARIOUS FACTORS
Creators: name: Saranya Thongsook
Publisher: name: Pibulsongkram Rajabhat University
Year: 2022
Subjects: Binary logistics regression
Opportunities for further study
Pibulsongkram Rajabhat University
Model averaging

description: Life Sciences and Environment Journal, 23, 2, 306-323
Slow Conformational Dynamics at C2′-endo Nucleotides in RNA
Creators: name: Gherghe, Costin M.
name: Krahn, Joseph M.
name: Thompson, Nancy L.
name: Weeks, Kevin M.
name: Mortimer, Stefanie A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: RNA molecules undergo local conformational dynamics on timescales spanning picoseconds to minutes. Slower local motions have the greater potential to govern RNA folding, ligand recognition, and ribonucleoprotein assembly reactions but are difficult to detect in large RNAs with complex structures. RNA SHAPE chemistry employs acylation of the ribose 2'-hydroxyl position to measure local nucleotide flexibility in RNA and is well-characterized by a mechanism in which each nucleotide samples unreactive (closed) and reactive (open) states. We monitor RNA conformational dynamics over distinct time domains by varying the electrophilicity of the acylating reagent. Select C2'-endo nucleotides are nonreactive toward fast reagents but reactive toward slower SHAPE reagents in both model RNAs and in a large RNA with a tertiary fold. We conclude, first, that the C2'-endo conformation by itself does not govern SHAPE reactivity. However, some C2'-endo nucleotides undergo extraordinarily slow conformational changes, on the order of 10(-4) s(-1). Due to their distinctive local dynamics, C2'-endo nucleotides have the potential to function as rate-determining molecular switches and are likely to play central, currently unexplored, roles in RNA folding and function.
Solution Structures of Chemoenzymatically Synthesized Heparin and Its Precursors
Creators: name: McCallum, Scott A.
name: Jiménez-Barbero, Jesús
name: Linhardt, Robert J.
name: Xie, Jin
name: Nieto, Lidia
name: Zhang, Zhenqing
name: Corzana, Francisco
name: Liu, Jian
name: Chen, Miao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: We report the first chemoenzymatic synthesis of the stable isotope-enriched heparin from a uniformly labeled [13C,15N]N-acetylheparosan (-GlcA(1,4)GlcNAc-) prepared from E. coli K5. Glycosaminoglycan (GAG) precursors and heparin were formed from N-acetylheparosan by the following steps: chemical N-deacetylation and N-sulfonation leading to N-sulfoheparosan (-GlcA(1,4)GlcNS-); enzyme-catalyzed C5-epimerization and 2-O-sulfonation leading to undersulfated heparin (-IdoA2S(1,4)GlcNS-); enzymatic 6-O-sulfonation leading to the heparin backbone (-IdoA2S(1,4)GlcNS6S-); and selective enzymatic 3-O-sulfonation leading to the anticoagulant heparin, containing the GlcNS6S3S residue. Heteronuclear, multidimensional nuclear magnetic resonance spectroscopy was employed to analyze the chemical composition and solution structure of [13C,15N]N-acetylheparosan, precursors, and heparin. Isotopic enrichment was found to provide well-resolved 13C spectra with the high sensitivity required for conformational studies of these biomolecules. Stable isotope-labeled heparin was indistinguishable from heparin derived from animal tissues and is a novel reagent for studying the interaction of heparin with proteins.
Strong Correlation between SHAPE Chemistry and the Generalized NMR Order Parameter ( S 2 ) in RNA
Creators: name: Wilkinson, Kevin A.
name: Shajani, Zahra
name: Gherghe, Costin M.
name: Weeks, Kevin M.
name: Varani, Gabriele
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The functions of most RNA molecules are critically dependent on the distinct local dynamics that characterize secondary structure and tertiary interactions and on structural changes that occur upon binding by proteins and small molecule ligands. Measurements of RNA dynamics at nucleotide resolution set the foundation for understanding the roles of individual residues in folding, catalysis, and ligand recognition. In favorable cases, local order in small RNAs can be quantitatively analyzed by NMR in terms of a generalized order parameter, S2. Alternatively, SHAPE (selective 2'-hydroxyl acylation analyzed by primer extension) chemistry measures local nucleotide flexibility in RNAs of any size using structure-sensitive reagents that acylate the 2'-hydroxyl position. In this work, we compare per-residue RNA dynamics, analyzed by both S2 and SHAPE, for three RNAs: the HIV-1 TAR element, the U1A protein binding site, and the Tetrahymena telomerase stem loop 4. We find a very strong correlation between the two measurements: nucleotides with high SHAPE reactivities consistently have low S2 values. We conclude that SHAPE chemistry quantitatively reports local nucleotide dynamics and can be used with confidence to analyze dynamics in large RNAs, RNA-protein complexes, and RNAs in vivo.
Charge screening and carrier transport in AA-stacked bilayer graphene: tuning via a perpendicular electric field
Creators: name: Mohammadi, Yawar
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The static dielectric function in AA-stacked bilayer graphene (BLG), subjected to an electric field applied perpendicular to layers, is calculated analytically within the random phase approximation (RPA). This result is used to calculate the screened Coulomb interaction and the electrical conductivity. The screened Coulomb interaction, which here can be tuned by the perpendicular electric field, shows a power-law decay as $1/(γ^{2}+V^2)$ at long-distance limit where $V$ and $γ$ are the electrical potential and the inter-layer hopping energy respectively, indicating that the Coulomb interaction is suppressed at high perpendicular electric fields. Furthermore, Our results for the effect of the short-range and the long-range (Coulomb) scattering on the electrical conductivity show that the shot-range scattering yields a constant electrical conductivity which is not affected by the perpendicular electric filed. While the electrical conductivity limited by the Coulomb scattering is enhanced by the perpendicular electric field and increases linearly in $V^2$ at small $V$ with a finite value at $V=0$, indicating that we can tune the electrical conductivity in AA-stacked BLG by applying a perpendicular electric field.
description: 6 pages, 3 figures
Ultrafast Dynamics and Anionic Active States of the Flavin Cofactor in Cryptochrome and Photolyase
Creators: name: Zhong, Dongping
name: Wang, Lijuan
name: Tan, Chuang
name: Li, Jiang
name: Song, Sang-Hun
name: Kao, Ya-Ting
name: Sancar, Aziz
name: Öztürk, Nuri
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: We report here our systematic studies of the dynamics of four redox states of the flavin cofactor in both photolyases and insect Type 1 cryptochromes. With femtosecond resolution, we observed ultrafast photoreduction of oxidized state (FAD) in subpicosecond and of neutral radical semiquinone (FADH•) in tens of picoseconds through intraprotein electron transfer mainly with a neighboring conserved tryptophan triad. Such ultrafast dynamics make these forms of flavin unlikely to be the functional states of the photolyase/cryptochrome family. In contrast, we find that upon excitation the anionic semiquinone (FAD•-) and hydroquinone (FADH-) have longer lifetimes that are compatible with high-efficiency intermolecular electron transfer reactions. In photolyases, the excited active state (FADH-*) has a long (nanosecond) lifetime optimal for DNA-repair function. In insect Type 1 cryptochromes known to be blue-light photoreceptors the excited active form (FAD•-*) has complex deactivation dynamics on the time scale from a few to hundreds of picoseconds, which is believed to occur through conical intersection(s) with a flexible bending motion to modulate the functional channel. These unique properties of anionic flavins suggest a universal mechanism of electron transfer for the initial functional steps of the photolyase/cryptochrome blue-light photoreceptor family.
Vicinal Feature Statistics Augmentation for Federated 3D Medical Volume Segmentation
Creators: name: Huang, Yongsong
name: Xie, Wanqing
name: Li, Mingzhen
name: Cheng, Mingmei
name: Wu, Jinzhou
name: Wang, Weixiao
name: You, Jane
name: Liu, Xiaofeng
Publisher: name: arXiv
Year: 2023
Subjects: subject: Image and Video Processing (eess.IV)
subject: Artificial Intelligence (cs.AI)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Medical Physics (physics.med-ph)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Federated learning (FL) enables multiple client medical institutes collaboratively train a deep learning (DL) model with privacy protection. However, the performance of FL can be constrained by the limited availability of labeled data in small institutes and the heterogeneous (i.e., non-i.i.d.) data distribution across institutes. Though data augmentation has been a proven technique to boost the generalization capabilities of conventional centralized DL as a "free lunch", its application in FL is largely underexplored. Notably, constrained by costly labeling, 3D medical segmentation generally relies on data augmentation. In this work, we aim to develop a vicinal feature-level data augmentation (VFDA) scheme to efficiently alleviate the local feature shift and facilitate collaborative training for privacy-aware FL segmentation. We take both the inner- and inter-institute divergence into consideration, without the need for cross-institute transfer of raw data or their mixup. Specifically, we exploit the batch-wise feature statistics (e.g., mean and standard deviation) in each institute to abstractly represent the discrepancy of data, and model each feature statistic probabilistically via a Gaussian prototype, with the mean corresponding to the original statistic and the variance quantifying the augmentation scope. From the vicinal risk minimization perspective, novel feature statistics can be drawn from the Gaussian distribution to fulfill augmentation. The variance is explicitly derived by the data bias in each individual institute and the underlying feature statistics characterized by all participating institutes. The added-on VFDA consistently yielded marked improvements over six advanced FL methods on both 3D brain tumor and cardiac segmentation.
description: 28th biennial international conference on Information Processing in Medical Imaging (IPMI 2023): Oral Paper
بحث الدلالات اللونية للأزياء في عروض المسرح المدرسي.pdf
Creators: name: الدغلاوي, حيدر جعفر
Publisher: name: figshare
Year: 2022
Subjects: Drama
Performing Arts

description: تمثل الأزياء المسرحية مع بقية عناصر العرض المسرحي الجانب المرئي ذات الطيف الواسع الشاغل لفضاء العرض ، اذ تعمل على الكشف عن أبعاد الشخصية ( الفسيولوجي ، سوسيولوجي ، سيكولوجي ) فضلاً عن زمكان أحداث الحكاية . ويتشكل اللون في الزي على وفق الضرورات الدرامية من جهة والشخصيات من جهة اخرى ، لنجد أن العلاقة بين الشخصية واللون في الزي علاقة جدلية تعمل على إثارة المتلقي فكريا ومعرفيا بوساطة الدلالات اللونية للزي المسرحي . ومن هنا قدم الباحث دراسته الموسومة بـ ( الدلالات اللونية للأزياء في عروض المسرح المدرسي ( مسرحية غابة اليوتيبيا انموذجاً ) ، في ضوء اربعة فصول على وفق المنهج العلمي البحثي ساعياً لتحقيق هدف البحث الذي يتلخص بالكشف عن الدلالة اللونية في أزياء مسرحية غابة اليوتيبيا . وقد خلص البحث الى مجموعة من النتائج أهمها : أحالت الازياء دلالات من الناحية الاجتماعية للشخصية اذ أحالها المخرج الى الرمز السياسي وبخاصة في شخصية الديك الذي عبر عنه بالفنان في زمن النظام البائد ، وكذلك الحال مع شخصية الكلب الذي عبرت ازياءه وإكسسواراته عن مفهوم الحكومة في تلك الحقبة .
قضايا حقوق الإنسان ومعالجاتها الإخراجية في العرض المسرحي العراقي
Creators: name: الدغلاوي, حيدر جعفر
name: الدغلاوي, حيدر جعفر
Publisher: name: figshare
Year: 2022
Subjects: subject: 190404 Drama, Theatre and Performance Studies
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: حظي موضوع هذه الرسالة بشيء كبير من الاهتمام في السنوات التي تلت التغيير في العراق عام ( 2003م ) ، لما له من اهمية كبرى في سمو ورفعة الانسان ، اذ لا يختلف اثنان حول أهمية حقوق الإنسان ، كما لا يمكن التشكيك بالدور الفاعل لتلك الحقوق في تخفيف المآسي التي يتحملها الإنسان جراء الانتهاكات المستمرة لحقوقه الاساسية .وبظهور المتغيرات المهمة في مختلف الأصعدة لاسيما المسرح بوصفه من اهم مراحل النشاط الانساني المتطور ، دخلت مفاهيم حقوق الانسان عهداً جديداً من التداخل والتفاعل مع مفردات الدراما المسرحية المختلفة وأدواتها المتعددة ، ومن ثم كانت ولا تزال آثاراً كبيرة وواسعة عكسها العرض المسرحي على ممارسة الانسان لحقوقه المختلفة . فالمسرح مؤسسة ثقافية اجتماعية يتفاعل مع كل المتغيرات والمستجدات ، فَلم يكن يوماً ما بعيداً عن قضايا الإنسان بل كان عوناً له في سعيه الدؤوب لتحقيق ما يحاول الإنسان تحصيله على صعيد حقوقه الطبيعية ، بوصفها معايير أساسية لا يمكن للناس ان يعيشوا بكرامة كبشر من دونها ، فهي أساس الحرية والعدالة والمساواة .فمن الأهمية بمكان ان يهتم المخرجون المسرحيون العراقيون بمعالجة قضايا حقوق الانسان في العرض المسرحي ، وان تتجه موضوعات العروض المسرحية لتتقصى حاجات الانسان الأساسية ، وان يكون إشباع تلك الحاجات من الغايات التي يبتغيها العرض المسرحي . ومن هنا قدم الباحث دراسته الموسوم بـ ( قضايا حقوق الإنسان ومعالجاتها الإخراجية في العرض المسرحي العراقي )
Lattice cluster theory for polymer melts with specific interactions
Creators: name: Xu, Wen-Sheng
name: Freed, Karl F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Despite the long-recognized fact that chemical structure and specific interactions greatly influence the thermodynamic properties of polymer systems, a predictive molecular theory that enables systematically addressing the role of chemical structure and specific interactions has been slow to develop even for polymer melts. While the lattice cluster theory (LCT) provides a powerful vehicle for understanding the influence of various molecular factors, such as monomer structure, on the thermodynamic properties of polymer melts and blends, the application of the LCT has heretofore been limited to the use of the simplest polymer model in which all united atom groups within the monomers of a species interact with a common monomer averaged van der Waals energy. Thus, the description of a compressible polymer melt involves a single van der Waals energy. As a first step towards developing more realistic descriptions to aid in the analysis of experimental data and the design of new materials, the LCT is extended here to treat models of polymer melts in which the backbone and side groups have different interaction strengths, so three energy parameters are present, namely, backbone-backbone, side group-side group, and backbone-side group interaction energies. Because of the great algebraic complexity of this extension, we retain maximal simplicity within this class of models by further specializing this initial study to models of polymer melts comprising chains with poly($n$-$α$-olefin) structures where only the end segments on the side chains may have different, specific van der Waals interaction energies with the other united atom groups. An analytical expression for the LCT Helmholtz free energy is derived for the new model. Illustrative calculations are presented to demonstrate the degree to which the thermodynamic properties of polymer melts can be controlled by specific interactions.
description: 16 pages, 7 figures, to be published in J. Chem. Phys
صور الموت في العرض المسرحي العراقي
Creators: name: الدغلاوي, حيدر جعفر
name: الدغلاوي, حيدر جعفر
Publisher: name: figshare
Year: 2022
Subjects: subject: 190404 Drama, Theatre and Performance Studies
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: يتناول البحث مفهوم الموت بوصفه من الظواهر المهمة التي ألقت بظلالها على طبيعة الفرد وكيانه . وأهتمت الحضارات والديانات الإنسانية بشقيها السماوية والوضعية بالموت وتباينت النظرة له كل حسب معتقداته وسلوكياته. ومع تطور الفكر الإنساني أخذت تظهر تيارات ومدارس في مختلف العلوم بدراسة تلك الظاهرة. وبخاصة بعد اندلاع الحرب العالمية وما أفرزته من إرهاصات في حياة الإنسان على كافة الاصعدة لاسيما الاجتماعي والاقتصادي ونظراً لما يتمتع به المسرح من خصوصية في الاتصال والتلقي جاءت تلك الدراسة لتسلط الضوء على ظاهرة الموت وقد تضمنت هذه الدراسة مقدمة البحث التي عرض فيها الباحثان مشكلة البحث وأهميته وهدفه. ثم الاطار النظري الذي تناول تأسيساً نظرياً للبحث اشتمل على مبحثين هما: الموت في الحضارات والديانات القديمة والثاني: الموت في المسرح العالمي وخرج الباحثان بمجموعة من المؤشرات أعتمدها في تحليل نموذج عينة البحث والتي تحددت بنموذج للكاتب علي عبدالنبي الزيدي والتي تتوافق مع هدف البحث. وبعد التحليل خرج الباحثان بمجموعة نتائج منها: 1. أثار العرض حفيظة بعض المتخصصين من خلال الجرأة في كسر حاجز التابو وتهشيم فكرة المقدس. 2. تعددت صور الموت في العرض فتارة بين التفجيرات وتارة أخرى بين الخطف والقتل. 3. أضفت بعض الرموز صوراً مضمرة للموت ومنها العباءة.
Duality invariance of $s \ge 3/2$ fermions in AdS
Creators: name: Deser, S.
name: Seminara, D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show that in D=4 AdS, $s\ge 3/2$ partially massless (PM) fermions retain the duality invariances of their flat space massless counterparts. They have tuned ratios $ {m^2}/{M^2}\ne 0$ that turn them into sums of effectively massless unconstrained helicity $\pm(s,\cdots,\frac{3}{2})$ excitations, shorn of the lowest (non-dual)\helicity $\pm \frac{1}{2}$-rung and -more generally- of succeeding higher rung as well. Each helicity mode is separately duality invariant, like its flat space counterpart.
description: 3 pages
EFFECT OF SEEDING AGE AT TRANSPLANTING AND WATER REGIMES ON GROWTH AND YIELD OF RICE CV. PHITSANULOK 2
Creators: name: Karun Phungbunhan
Publisher: name: Pibulsongkram Rajabhat University
Year: 2022
Subjects: Age at transplanting
Water regimes
Yield

description: Life Sciences and Environment Journal, 23, 2, 334-344
Theorem on the existence of a nonzero energy gap in adiabatic quantum computation
Creators: name: Zhang, Da-Jian
name: Yu, Xiao-Dong
name: Tong, D. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Adiabatic quantum computation, based on the adiabatic theorem, is a promising alternative to conventional quantum computation. The validity of an adiabatic algorithm depends on the existence of a nonzero energy gap between the ground and excited states. However, it is difficult to ascertain the exact value of the energy gap. In this paper, we put forward a theorem on the existence of nonzero energy gap for the Hamiltonians used in adiabatic quantum computation. It can help to effectively identify a large class of the Hamiltonians without energy-level crossing between the ground and excited states.
description: 5 pages, 3 figures
Ultrafast Dynamics of Flavins in Five Redox States
Creators: name: He, Ting-Fang
name: Kao, Ya-Ting
name: Zhong, Dongping
name: Guo, Lijun
name: Wang, Lijuan
name: Sancar, Aziz
name: Saxena, Chaitanya
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: We report here our systematic studies of excited-state dynamics of two common flavin molecules, FMN and FAD, in five redox states of oxidized form, neutral and anionic semiquinones, and neutral and anionic fully-reduced hydroquinones in solution and in inert protein environments with femtosecond resolution. Using protein environments, we are able to stabilize two semiquinone radicals and thus observed their weak emission spectra. Significantly, we observed a strong correlation between their excited-state dynamics and the planarity of their flavin isoalloxazine ring. For a bent ring structure, we all observed ultrafast dynamics from a few to hundreds of picoseconds and strong excitation-wavelength dependence of emission spectra, indicating deactivation during relaxation. A butterfly bending motion is invoked to get access to conical intersection(s) to facilitate deactivation. These states include the anionic semiquinone radical and fully-reduced neutral and anionic hydroquinones in solution. In a planar configuration, flavins have a long lifetime in nanoseconds except for the stacked conformation of FAD, where the intramolecular electron transfer between the ring and the adenine moiety in 5-9 ps as well as the subsequent charge recombination in 30-40 ps were observed. These observed distinct dynamics, controlled by the flavin ring flexibility, are fundamental to flavoenzyme’s functions as observed in photolyase with a planar structure to lengthen the lifetime to maximize DNA repair efficiency and in insect Type 1 cryptochrome with a flexible structure to vary the excited-state deactivation to modulate the functional channel.
High Speed Friction Microscopy and Nanoscale Friction Coefficient Mapping
Creators: name: Bosse, James L.
name: Lee, Sungjun
name: Huey, Bryan D.
name: Andersen, Andreas Sø
name: Sutherland, Duncan S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: As mechanical devices in the nano/micro length scale are increasingly employed, it is crucial to understand nanoscale friction and wear especially at technically relevant sliding velocities. Accordingly, a novel technique has been developed for Friction Coefficient Mapping (FCM), leveraging recent advances in high speed AFM. The technique efficiently acquires friction versus force curves based on a sequence of images at a single location, each with incrementally lower loads. As a result, true maps of the coefficient of friction can be uniquely calculated for heterogeneous surfaces. These parameters are determined at a scan velocity as fast as 2 mm/s for microfabricated SiO2 mesas and Au coated pits, yielding results that are identical to traditional speed measurements despite being ~1000 times faster. To demonstrate the upper limit of sliding velocity for the custom setup, the friction properties of mica are reported from 200 μm/sec up to 2 cm/sec. While FCM is applicable to any AFM and scanning speed, quantitative nanotribology investigations of heterogeneous sliding or rolling components are therefore uniquely possible, even at realistic velocities for devices such as MEMS, biological implants, or data storage systems.
La$_{2-x}$Ba$_x$CuO$_4$ as a superconducting Rosetta Stone
Creators: name: Tranquada, John M.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The high-temperature superconductivity in layered cuprates discovered by Bednorz and Müller arrived as a shock. Gradually, the presence of competing orders, such as antiferromagnetism and charge order, were discovered; however, the relationship to the superconductivity has been confusing. It so happens that the original cuprate superconductor family La$_{2-x}$Ba$_x$CuO$_4$ contains all of the relevant phases, with extreme competition among them, and analysis of these phases provides strong clues to the nature of the superconductivity in cuprates.
description: 10 pages, 4 figures, accepted manuscript
A common supersolid low-density skin sliperizing ice and toughening water surface
Creators: name: Zhang, Xi
name: Huang, Yongli
name: Ma, Zengsheng
name: Zhou, Yichun
name: Zheng, Weitao
name: Zhou, Ji
name: Sun, Chang Q.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Skins of water and ice share the same attribute of supersolidity characterized by the identical H-O vibration frequency of 3450 cm-1. Molecular undercoordination and inter-electron-pair repulsion shortens the H-O bond and lengthen the O:H nonbond, leading to a dual process of nonbonding electron polarization. This relaxation-polarization process enhances the dipole moment, elasticity,viscosity, thermal stability of these skins with 25% density loss, which is responsible for the hydrophobicity and toughness of water skin and for the slippery of ice.
description: arXiv admin note: text overlap with arXiv:1401.8045
Acquisition of a Potent and Selective TC-PTP Inhibitor via a Stepwise Fluorophore-Tagged Combinatorial Synthesis and Screening Strategy
Creators: name: Zhang, Sheng
name: Gunawan, Andrea
name: Chen, Lan
name: Lawrence, David S.
name: Zhang, Zhong-Yin
name: Luo, Yong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Protein tyrosine phosphatases (PTPs) regulate a broad range of cellular processes including proliferation, differentiation, migration, apoptosis, and the immune responses. Dysfunction of PTP activity is associated with cancers, metabolic syndromes, and autoimmune disorders. Consequently, small molecule PTP inhibitors should not only serve as powerful tools to delineate the physiological roles of these enzymes in vivo, but also as lead compounds for therapeutic development. We describe a novel stepwise fluorophore-tagged combinatorial library synthesis and competitive fluorescence polarization screening approach that transforms a weak and general PTP inhibitor into an extremely potent and selective TC-PTP inhibitor with highly efficacious cellular activity. The result serves as a proof-of-concept in PTP inhibitor development, as it demonstrates the feasibility of acquiring potent, yet highly selective, cell permeable PTP inhibitory agents. Given the general nature of the approach, this strategy should be applicable to other PTP targets.
AN ANALYSIS OF THE FACTORS AFFECTING THE DECISION TO PURCHASE SUNSCREEN PRODUCTS
Creators: name: Krieng  Kitbumrungrat
Publisher: name: Pibulsongkram Rajabhat University
Year: 2022
Subjects: Sunscreen products
Sunscreen cosmetic
Distribution and advertising channels
Marketing mix
UV rays

description: Life Sciences and Environment Journal, 23, 2, 345-360
External validation of a machine learning classifier to identify unhealthy alcohol use in hospitalized patients
Creators: name: Lin, Yiqi
name: Sharma, Brihat
name: Thompson, Hale M
name: Boley, Randy
name: Perticone, Kathryn
name: Chhabra, Neeraj
name: Afshar, Majid
name: Karnik, Niranjan S
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: BACKGROUND AND AIMS: Unhealthy alcohol use (UAU) is one of the leading causes of global morbidity. A machine learning approach to alcohol screening could accelerate best practices when integrated into electronic health record (EHR) systems. This study aimed to validate externally a natural language processing (NLP) classifier developed at an independent medical center. DESIGN: Retrospective cohort study. SETTING: The site for validation was a midwestern United States tertiary-care, urban medical center that has an inpatient structured universal screening model for unhealthy substance use and an active addiction consult service. PARTICIPANTS/CASES: Unplanned admissions of adult patients between October 23, 2017 and December 31, 2019, with EHR documentation of manual alcohol screening were included in the cohort (n = 57 605). MEASUREMENTS: The Alcohol Use Disorders Identification Test (AUDIT) served as the reference standard. AUDIT scores ≥5 for females and ≥8 for males served as cases for UAU. To examine error in manual screening or under-reporting, a post hoc error analysis was conducted, reviewing discordance between the NLP classifier and AUDIT-derived reference. All clinical notes excluding the manual screening and AUDIT documentation from the EHR were included in the NLP analysis. FINDINGS: Using clinical notes from the first 24 hours of each encounter, the NLP classifier demonstrated an area under the receiver operating characteristic curve (AUCROC) and precision-recall area under the curve (PRAUC) of 0.91 (95% CI = 0.89-0.92) and 0.56 (95% CI = 0.53-0.60), respectively. At the optimal cut point of 0.5, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 0.66 (95% CI = 0.62-0.69), 0.98 (95% CI = 0.98-0.98), 0.35 (95% CI = 0.33-0.38), and 1.0 (95% CI = 1.0-1.0), respectively. CONCLUSIONS: External validation of a publicly available alcohol misuse classifier demonstrates adequate sensitivity and specificity for routine clinical use as an automated screening tool for identifying at-risk patients.
Conservation of Side-Chain Dynamics Within a Protein Family
Creators: name: Lee, Andrew L.
name: Fuentes, Ernesto J.
name: Law, Anthony B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: The question of protein dynamics and its relevance to function is currently a topic of great interest. Proteins are particularly dynamic at the side-chain level on the timescale of picoseconds to nanoseconds. Here, we present a comparison of NMR-monitored side-chain motion between three PDZ domains of ∼30% sequence identity and show that the side-chain dynamics display non-trivial conservation. Methyl 2H relaxation was carried out to determine side-chain order parameters (S2), which were found to be more similar than naively expected from sequence, local packing, or a combination of the two. Thus, the dynamics of a rather distant homolog appears to be an excellent predictor of a protein's side-chain dynamics, and, on average, better than current structure-based methods. Fast side-chain dynamics therefore display a high level of organization associated with global fold. Beyond simple conservation, the analysis herein suggests that the pattern of side-chain flexibility has significant contributions from non-local elements of the PDZ fold, such as correlated motions, and that the conserved dynamics may directly support function.
Controlling Peptide Folding with Repulsive Interactions between Phosphorylated Amino Acids and Tryptophan
Creators: name: Waters, Marcey L.
name: Riemen, Alexander J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Phosphorylated amino acids were incorporated into a designed β-hairpin peptide to study the effect on β-hairpin structure when the phosphate group is positioned to interact with a tryptophan residue on the neighboring strand. The three commonly phosphorylated residues in biological systems, serine, threonine, and tyrosine, were studied in same β-hairpin system. It was found that phosporylation destabilizes the hairpin structure by approximately 1.0 kcal/mol regardless of the type of phosphorylated residue. In contrast, destabilization due to glutamic acid was about 0.3 kcal/mol. Double mutant cycles and pH studies are consistent with a repulsive interaction as the source of destabilization. These findings demonstrate a novel mechanism by which phosphorylation may influence protein structure and function.
ANALOGY THEORY OF MATHEMATICS AND PHYSICS MODELING OF THE TERMINAL VELOCITY AND KINETIC ENERGY OF THE 5000 METRES SPRINT VIA NEWTON’S SECOND LAW
Creators: name: Artit Hutem
Publisher: name: Pibulsongkram Rajabhat University
Year: 2022
Subjects: Time dependent velocity
Time dependent Kinetic energy
Correlation coefficient

description: Life Sciences and Environment Journal, 23, 2, 361-372
title: Degenerative lumbar spine: A quick guide for imaging diagnosis.
Creators: name: García Duitama, Iván
Publisher: name: European Society of Muscoskeletal Radiology
Year: 2018
Subjects: subject: Education and training
subject: Structured reporting
subject: eLearning
subject: Diagnostic procedure
subject: MR
subject: CT
subject: Neuroradiology spine
subject: Musculoskeletal spine

description: Learning objectives Background Imaging findings OR Procedure Details Conclusion References Personal Information
description: Learning objectives: Present a friendly and concise guide to the imaging diagnosis of degenerative lumbar disease. Review future perspectives from the diagnostic imaging point of...
Formation of S- [1-( N 2 -Deoxyguanosinyl)methyl]glutathione between Glutathione and DNA Induced by Formaldehyde
Creators: name: Lu, Kun
name: Ball, Louise M.
name: Ye, Wenjie
name: Gold, Avram
name: Swenberg, James A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Formaldehyde is an essential metabolic intermediate in human cells and can also enter into the body through environmental exposures. It is classified as a human and animal carcinogen according to the International Agency for Research on Cancer (IARC). Previous research has demonstrated that formaldehyde is genotoxic, causing mutations in multiple genes. However, no exogenous formaldehyde-induced DNA adducts have been detected in animals after inhalation exposure, although formaldehyde can result in N6-deoxyadenosine, N2-deoxyguanosine and N4-deoxycytidine adducts in vitro. This can be partially attributed to the rapid metabolism of formaldehyde by glutathione (GSH)-dependent enzyme systems. Among the intermediates in the pathway of formaldehyde detoxication, S-hydroxymethylglutathione is a reactive species and has the potential to further conjugate with DNA bases. Here, we have demonstrated the formation of S-[1-(N2-deoxyguanosinyl)methyl]glutathione between glutathione and DNA in the presence of formaldehyde. This adduct is unique because of the involvement of S-hydroxymethylglutathione which is a key player during the detoxication of formaldehyde.
title: Accessory plantaris muscle. Pictorial review and clinical implications
Creators: name: Pikoulas, Konstantinos
Publisher: name: European Society of Muscoskeletal Radiology
Year: 2018
Subjects: subject: Congenital
subject: Normal variants
subject: Diagnostic procedure
subject: MR
subject: Musculoskeletal soft tissue
subject: Extremities
subject: Anatomy

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: The plantaris is a small muscle that exists in about 90% of people. It originates from the lateral supracondylar ridge of the femur, and inserts into the Achilles tendon or at the posterior part of the medial surface of the calcaneus [1]. If it is...
THE INFECTION OF LARVAL TREMATODES IN POND SNAIL, FILOPALUDINA MARTENSI MARTENSI FROM CHIANG MAI PROVINCE
Creators: name: Pheravut Wongsawad
Publisher: name: Pibulsongkram Rajabhat University
Year: 2022
Subjects: Filopaludina martensi martensi
Trematodes
Cercaria
Metacercaria
Chiang Mai

description: Life Sciences and Environment Journal, 23, 2, 373-392
title: Usefulness of quantitative MRI with chemical shift imaging (Dixon) in detecting diffuse bone marrow infiltration in patients with multiple myeloma without focal lesion
Creators: name: Berardo, Sara
Publisher: name: European Society of Muscoskeletal Radiology
Year: 2018
Subjects: subject: Cancer
subject: Observer performance
subject: MR-Functional imaging
subject: MR
subject: Oncology
subject: Musculoskeletal bone

description: Purpose Methods and Materials Results Conclusion References Personal Information
description: Purpose: Diffusion-weighted imaging (DWI) images in association with ADC maps and chemical shift (CS) in myeloma are introduced as problem-solving sequences to evaluate bone marrow abnormalities. In our study we tried to understand the utility of Dixon...
An Auction-based Approach to Control Automated Warehouses using Smart Vehicles
Creators: name: Di Marino, Emiliano
Publisher: name: Universita degli studi di Salerno
Year: 2020
Subjects: subject: ING-INF/04 AUTOMATICA
subject: Petri Nets
subject: Discrete event system
subject: Auction-based architectures

description: 2018 - 2019
description: In the field of logistics, the study of systems that follow the recommended requirements of the ``Industry 4.0'' is now of paramount importance. Since traditional hierarchical and centralized control architectures have been employed to solve most of the basic problems in this context, many researchers have shifted their focus to the study of more flexible ones. This is mainly due to the fact that nowadays vehicles are able to work on their own and interact with each other exchanging messages. In the studied application domain, the main contribution of this thesis concerns the development of an auction-based control architecture for the control of modern AWSs focusing the efforts on the mission assignment problem. To face with the problem of the system performance evaluation and analysis and to support the development of auction-based control algorithms, a highly modular and compact hybrid model based on PNs together with heuristic based control laws was designed. In addition, an automated model synthesis procedure was also developed, since the manual creation of the provided model can be a very demanding activity. To remedy the lack of design methods, that is still a problem for algorithms based on auction mechanisms, a design methodology for such algorithms is also devised: results to the problem of design/tuning appropriately the proposed auction-based control algorithm are also presented. Simulation results encourage the adoption of auction-based control architectures in logistic environments as effective and efficient solutions. At the same time, modularity, real-time capabilities, robustness, services orientation capabilities and scalability are delivered to the whole system. [edited by Author]
title: US of the sciatic nerve: a detailed didactic approach
Creators: name: Orlandi, Davide
Publisher: name: European Society of Muscoskeletal Radiology
Year: 2018
Subjects: subject: Education and training
subject: Technical aspects
subject: Education
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Neuroradiology peripheral nerve
subject: Musculoskeletal system
subject: Musculoskeletal soft tissue

description: Learning objectives Background Imaging findings OR Procedure Details Conclusion References Personal Information
description: Learning objectives: The purpose of our educational exhibit is to: 1. illustrate the normal anatomy and normal US appearance of the sciatic nerve; 2. describe a systematic technique for US evaluation of such structure; 3. produce anatomical schemes with didactic purpose...
Generation of Vortex Beams with Strong Longitudinally Polarized Magnetic Field by Using a Metasurface
Creators: name: Veysi, Mehdi
name: Guclu, Caner
name: Capolino, Filippo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: A novel method of generation and synthesis of azimuthally E-polarized vortex beams is presented. Along the axis of propagation such beams have a strong longitudinally polarized magnetic field where ideally there is no electric field. We show how these beams can be constructed through the interference of Laguerre-Gaussian beams carrying orbital angular momentum. As an example, we present a metasurface made of double-split ring slot pairs and report a good agreement between simulated and analytical results. Both a high magnetic-to-electric-field contrast ratio and a magnetic field enhancement are achieved. We also investigate the metasurface physical constraints to convert a linearly polarized beam into an azimuthally E- polarized beam and characterize the performance of magnetic field enhancement and electric field suppression of a realistic metasurface. These findings are potentially useful for novel optical spectroscopy related to magnetic dipolar transitions and for optical manipulation of particles with spin and orbital angular momentum.
description: 11 pages, 9 figures
EVALUATION OF HEAVY METALS CONTAMINATION AND BIOACCUMULATION IN CITRUS MAXIMA (CITRUS MAXIMA (BURM.) MERRILL) IN PHO PRATHAP CHANG SUB-DISTRICT, PHO PRATHAP CHANG DISTRICT, PHICHIT PROVINCE
Creators: name: Piyada Wachirawongsakorn
Publisher: name: Pibulsongkram Rajabhat University
Year: 2022
Subjects: Heavy metals
Contamination
Bioaccumulation
Citrus maxima
Soil

description: Life Sciences and Environment Journal, 23, 2, 393-408
Panduan Praktis Manajemen OJS 3.3.x
Creators: name: Yunus, Muhammad
Publisher: name: Zenodo
Year: 2022
Subjects: panduan ojs 3.3
ojs 3.3.x

description: Membahas teknis manajemen publikasi OJS 3.3.0.11 yang saat modul ini dibuat merupakan versi terbaru dari seri OJS 3.3.x. Pembahasan dimulai dari register akun user, pengelolaan naskah oleh editor sampai dengan proses penjadwalan. Materi disampaikan pada Workshop Pengelolaan Jurnal Gayatri dan Jurnal Terob di Kampus STKW Surabaya pada tanggal 22 Oktober 2022.
THE PROGRESSING MACHINE OR LEARNING AS THE ART OF THE RIGHT MEASURE
Creators: name: De Nápoles, Miguel Gullander Metello
Publisher: name: Zenodo
Year: 2001
Subjects: Progressive machine, human-scale, system, structure, development, globalisation, education, iron law of oligarchy, colonialism, individuals/subjects, engineering, consumerism, self, taxonomy, repetition/routine, passivity, boredom, transgression, alienation, addiction, nomad spirit, right measure/contemplation, learning, relevance, adequacy, art, creativity, turning point, change, flux, chaos, holism.

description: This study is a long reflection, within a philosophical and humanistic tradition, about some mechanistic structures that seem to be the ridgepoles our society, and the main contributors for the engineering of subjects of this same society. These mechanistic structures, of which Education is part, are in our opinion, obeying to essentially rigid, isomorphic and mechanic laws, which clearly represent an inadequate perception of the dynamics implicit in each context, each situation, each environment as it is. These structures are what we call a progressing machine that is being globalised under various pretexts, namely education, development, modernity, etc. However, being a machine, its responses to challenge are restricted to a limited set of possibilities, whereas reality’s challenges demand much more than that as a response. In our opinion this systematic failure that is either felt or suspected both on a macro-scale, by countries and nations; or in a micro-scale, by the individuals, in bringing about such development, such education, is result of that inadequate and mainly mechanistic response that is being given to the multiple and interrelated challenges that our times present. Within this work we argue that what is clearly amiss both in society, in general, and in education, in particular, is a creative response as opposed to a mechanistic one. A response that represents something else beyond the pre-established set of possible responses. A creative response with the quality and nature of art itself. The art of the right measure.