cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Real Space Visualization of Thermomagnetic Irreversibility within Supercooling and Superheating Spinodals in $Mn_{1.85}Co_{0.15}Sb$ using Scanning Hall Probe Microscopy
Creators: name: Kushwaha, Pallavi
name: Lakhani, Archana
name: Rawat, R
name: Banerjee, A
name: Chaddah, P
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Phase coexistence across disorder-broadened and magnetic-field-induced first order antiferromagnetic to ferrimagnetic transition in polycrystalline $Mn_{1.85}Co_{0.15}Sb$ has been studied mesoscopically by Scanning Hall Probe Microscope at 120K and up to 5 Tesla magnetic fields. We have observed hysteresis with varying magnetic field and the evolution of coexisting antiferromagnetic and ferrimagnetic state on mesoscopic length scale. These studies show that the magnetic state of the system at low field depends on the path followed to reach 120 K. The low field magnetic states are mesoscopically different for virgin and second field increasing cycle when 120 K is reached by warming from 5K, but are the same within measurement accuracy when the measuring temperature of 120K is reached from 300K by cooling.
СНИЖЕНИЕ СИЛЫ ХОЛОДНОЙ ШТАМПОВКИ ВЫДАВЛИВАНИЕМ ДЕТАЛЕЙ ТИПА СТАКАНОВ СО СТУПЕНЧАТЫМИ ПОЛОСТЯМИ
Creators: name: КОРОБОВА НАТАЛЬЯ ВАСИЛЬЕВНА
name: ДМИТРИЕВ АЛЕКСАНДР МИХАЙЛОВИЧ
Publisher: name: Известия Тульского государственного университета. Технические науки
Year: 2020
Subjects: ХОЛОДНАЯ ШТАМПОВКА
ВЫДАВЛИВАНИЕ
СТАКАНЫ СО СТУПЕНЧАТЫМИ ПОЛОСТЯМИ
COLD STAMPING
EXTRUSION
GLASSES WITH STEPPED CAVITIES

description: В статье исследована зависимость величины деформирующей силы от конструкции и формы полости матрицы штампа. Представлены результаты экспериментальных исследований различия силы выдавливания заготовок гладкими и ступенчатыми пуансонами в неподвижно закрепленной и в освобожденной от крепления, так называемой, плавающей матрице. Установлена зависимость величины удельной силы на ступенчатом пуансоне от длины участка пуансона до ступени.
Faint, Evolving Radio AGN in SDSS Luminous Red Galaxies
Creators: name: Hodge, J. A.
name: Zeimann, G. R.
name: Becker, R. H.
name: White, R. L.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We detect and study the properties of faint radio AGN in Luminous Red Galaxies (LRGs). The LRG sample comprises 760,000 objects from a catalog of LRG photometric redshifts constructed from the Sloan Digital Sky Survey (SDSS) imaging data, and 65,000 LRGs from the SDSS spectroscopic sample. These galaxies have typical 1.4 GHz flux densities in the 10s-100s of microJy, with the contribution from a low-luminosity AGN dominating any contribution from star formation. To probe the radio properties of such faint objects, we employ a stacking technique whereby FIRST survey image cutouts at each optical LRG position are sorted by the parameter of interest and median-combined within bins. We find that median radio luminosity scales with optical luminosity (L_opt) as L_1.4 GHz ~ L_opt^(beta), where beta appears to decrease from beta ~ 1 at z = 0.4 to beta ~ 0 at z = 0.7, a result which could be indicative of AGN cosmic downsizing. We also find that the overall LRG population, which is dominated by low-luminosity AGN, experiences significant cosmic evolution between z = 0.2 and z = 0.7. This implies a considerable increase in total AGN heating for these massive ellipticals with redshift. By matching against the FIRST catalog, we investigate the incidence and properties of LRGs associated with double-lobed (FR I/II) radio galaxies. (Abridged)
description: 12 pages, 9 figures, Accepted by AJ
АНАЛИЗ ВЛИЯНИЯ УГЛОВ КОНУСНОСТИ ИНСТРУМЕНТА НА ХАРАКТЕР ТЕЧЕНИЯ МЕТАЛЛА И СИЛУ КОМБИНИРОВАННОГО ВЫДАВЛИВАНИЯ
Creators: name: ГУРОВА ОЛЬГА ЮРЬЕВНА
name: ЛАРИН СЕРГЕЙ НИКОЛАЕВИЧ
Publisher: name: Известия Тульского государственного университета. Технические науки
Year: 2020
Subjects: КОМБИНИРОВАННОЕ ВЫДАВЛИВАНИЕ
ПУАНСОН
МАТРИЦА
СИЛА
ТЕЧЕНИЕ МЕТАЛЛА
COMBINED EXTRUSION
PUNCH
DIE
FORCE
METAL FLOW

description: Установлен характер влияния степени деформации, углов конусности деформирующего пуансона и неподвижного пуансона на силу комбинированного выдавливания и условия течения металла в полости между инструментами. Получены зависимости, иллюстрирующие характер изменения сил процесса от исследуемых параметров.
Vamorolone: First Approval
Creators: name: Keam, Susan
Publisher: name: Adis Journals
Year: 2023
Subjects: Medicine

description: Declarations
Funding The preparation of this review was not supported by any external funding.
Authorship and Conflict of interest During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. Susan J. Keam is a contracted employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to this article and are responsible for its content.
Ethics approval, Consent to participate, Consent to publish, Availability of data and material, Code availability Not applicable.
Additional information about this Adis Drug Review can be found here. 
Abstract
Vamorolone (AGAMREE®) is an oral, selective, dissociative corticosteroid developed by ReveraGen BioPharma and Santhera Pharmaceuticals for the treatment of patients with muscular dystrophy. Vamorolone was approved in October 2023 for the treatment of Duchenne muscular dystrophy (DMD) in patients 2 years of age and older in the USA and received a positive opinion in the EU in October 2023 for the treatment of DMD in patients 4 years of age and older. This article summarizes the milestones in the development of vamorolone leading to this first approval for DMD.
© Springer Nature Switzerland AG 2023
ОЦЕНКА ВЛИЯНИЯ ГЕОМЕТРИИ РАБОЧЕГО ИНСТРУМЕНТА НА СИЛУ ВЫДАВЛИВАНИЯ ПРУТКОВОЙ ЗАГОТОВКИ КРУГЛОГО СЕЧЕНИЯ В КВАДРАТНУЮ МАТРИЦУ
Creators: name: ГУРОВА ОЛЬГА ЮРЬЕВНА
name: ПАСЫНКОВ АНДРЕЙ АЛЕКСАНДРОВИЧ
Publisher: name: Известия Тульского государственного университета. Технические науки
Year: 2020
Subjects: ОБРАТНОЕ ВЫДАВЛИВАНИЕ
ИНСТРУМЕНТ КВАДРАТНОГО СЕЧЕНИЯ
ИЗОТЕРМИЧЕСКОЕ ДЕФОРМИРОВАНИЕ
BACK EXTRUSION
SQUARE TOOL
ISOTHERMAL DEFORMATION

description: Рассмотрен процесс выдавливания прутковой заготовки круглого сечения в изотермических условиях. Проанализировано влияние величин радиусов скруглений рабочих кромок матрицы и пуансона на поведение материала при разных значениях редукции. Получены зависимости влияния радиусов скруглений рабочих кромок инструмента, редукции и скорости перемещения деформирующего инструмента на силу.
MPEC 2023-Y30 : 2023 YC
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 YC

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
АНАЛИЗ ФОРМИРОВАНИЯ ГЕОМЕТРИИ КРАЕВОЙ ЧАСТИ ИЗДЕЛИЯ ПРИ ВЫДАВЛИВАНИИ ПРУТКА В КВАДРАТНУЮ МАТРИЦУ
Creators: name: АБРАМОВ СЕРГЕЙ СЕРГЕЕВИЧ
name: ПАСЫНКОВА НАДЕЖДА СТАНИСЛАВОВНА
name: ПАСЫНКОВ АНДРЕЙ АЛЕКСАНДРОВИЧ
Publisher: name: Известия Тульского государственного университета. Технические науки
Year: 2020
Subjects: ОБРАТНОЕ ВЫДАВЛИВАНИЕ
КВАДРАТНАЯ МАТРИЦА
ФОРМОИЗМЕНЕНИЕ
ГЕОМЕТРИЯ
REVERSE EXTRUSION
SQUARE MATRIX
SHAPE CHANGING
GEOMETRY

description: Исследовано формоизменение прутковой цилиндрической заготовки в матрицу квадратного профиля. Проанализировано влияние различных геометрических и технологических параметров на формирование краевой части детали.
A Photometric Metallicity Estimate of the Virgo Stellar Overdensity
Creators: name: An, Deokkeun
name: Johnson, Jennifer A.
name: Beers, Timothy C.
name: Pinsonneault, Marc H.
name: Terndrup, Donald M.
name: Delahaye, Franck
name: Lee, Young Sun
name: Masseron, Thomas
name: Yanny, Brian
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We determine photometric metal abundance estimates for individual main-sequence stars in the Virgo Overdensity (VOD), which covers almost 1000 deg^2 on the sky, based on a calibration of the metallicity sensitivity of stellar isochrones in the gri filter passbands using field stars with well-determined spectroscopic metal abundances. Despite the low precision of the method for individual stars, we derive [Fe/H] = -2.0 +/-0.1 (internal) +/-0.5 (systematic) for the metal abundance of the VOD from photometric measurements of 0.7 million stars in the Northern Galactic hemisphere with heliocentric distances from ~10 kpc to ~20 kpc. The metallicity of the VOD is indistinguishable, within Delta [Fe/H] < 0.2, from that of field halo stars covering the same distance range. This initial application suggests that the SDSS gri passbands can be used to probe the properties of main-sequence stars beyond ~10 kpc, complementing studies of nearby stars from more metallicity-sensitive color indices that involve the u passband.
description: 5 pages, 3 figures, Accepted for publication in ApJ Letters
The development of a garrison mentality among the English in Lower Canada, 1793-1811
Creators: name: Greenwood, Frank Murray
Publisher: name: University of British Columbia
Year: 2011

description: The mutual antagonism of French and English speaking Canadians, during the first decade of the nineteenth century has been explained by historians in a variety of ways. Traditional French Canadian historiography attributes much of the trouble to the machinations and religious and racial bigotry of a handful of bureaucrats. The neo-nationalist school of the University of Montreal maintains that the conflict was the inevitable result of the "decapitation" of French Canadian society at the Conquest and the impossibility of two cultural "nations" coexisting harmoniously in the same political entity. A recurrent tendency in English historical writing has been to lay the blame on the irresponsibility of the nationalists who founded Le Canadien. The "Laurentian" school, including both English and French Canadian historians, postulates that the change from a fur trading to a grain and timber exporting colony and the emergence of rival agrarian and commercial interests were the main causes of the ethnic struggle. Without denying the elements of truth in all these interpretations, this study attempts to provide a more comprehensive understanding of English Canadian attitudes towards the French Canadians during the war against Revolutionary and Napoleonic France. It contends that such attitudes can be explained only by taking account of the English Canadian fear of an attack on the colony by French troops and an armed uprising by the French Canadians. The English Canadians found themselves in an ambiguous situation. The evidence at their disposal suggested— at almost any time during the period—that France might be planning an invasion of Lower Canada and they had no certain means of assessing the loyalty of the French Canadians. Because of their physical situation as an outnumbered minority and because they held strong convictions on the ease with which revolution could be brought about, they were disposed to make the most pessimistic interpretation of events which the twentieth century historian can see did not warrant serious alarm. While English Canadian fears were exaggerated, they were a major influence on the political history of the period. Dozens of political developments and issues from the language dispute of 1792-93 to governor Craig's Reign of Terror can be understood only by taking this factor into account. More generally, these fears virtually insured the breakdown of the Constitution of 1791, hardened English Canadian attitudes to French Canadian cultural survival, and contributed indirectly to the emergence of French Canadian nationalism.
Imaging an off-plane shear wave source with two-dimensional phononic-crystal lens
Creators: name: Chiang, Chen-Yu
name: Luan, Pi-Gang
Publisher: name: arXiv
Year: 2010
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: A two dimensional flat phononic crystal (PC) lens for focusing off-plane shear waves is proposed. The lens consists of a triangular lattice hole-array, embedded in solid matrix. Self-collimation effect is employed to guide the shear waves propagating through the lens along specific directions. Dirichlet-to-Neumann Maps (DtN) method is employed to calculate the band structure of the PC, which can avoid the problems of bad convergence and fake bands automatically in the void-solid PC structure. When the lens is illuminated by the off-plane shear waves emanating from a point source, a subwavelength image appears in the far-field zone. The imaging characteristics are investigated by calculating the displacement fields explicitly using the multiple-scattering method, and the results are in good agreement with the ray-trace predictions. Our results may provide insights for designing new phononic devices.
description: 15 pages, 6 figures. To appear in J. Phys. Cond. Matt. (2010)
MOESM2 of Lysine demethylase 2 (KDM2B) regulates hippo pathway via MOB1 to promote pancreatic ductal adenocarcinoma (PDAC) progression
Creators: name: Quan, Ming
name: Chen, Zhiqin
name: Jiao, Feng
name: Xiao, Xiuying
name: Xia, Qing
name: Chen, Jingde
name: Chao, Qian
name: Li, Yandong
name: Gao, Yong
name: Yang, Haiyan
name: Wang, Liwei
name: Cui, Jiujie
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 2: Table S2. Correlation between the clinicopathologic characteristics and YAP expression (n = 100).
title: New Methods, New Concepts
title: What Can Be Applied to Freshwater Periphyton?
titleType: Subtitle
Creators: name: Gubelit, Yulia I.
name: Grossart, Hans-Peter
Publisher: name: Universität Potsdam
Year: 2020

description: Microbial interactions play an essential role in aquatic ecosystems and are of the great interest for both marine and freshwater ecologists. Recent development of new technologies and methods allowed to reveal many functional mechanisms and create new concepts. Yet, many fundamental aspects of microbial interactions have been almost exclusively studied for marine pelagic and benthic ecosystems. These studies resulted in a formulation of the Black Queen Hypothesis, a development of the phycosphere concept for pelagic communities, and a realization of microbial communication as a key mechanism for microbial interactions. In freshwater ecosystems, especially for periphyton communities, studies focus mainly on physiology, biodiversity, biological indication, and assessment, but the many aspects of microbial interactions are neglected to a large extent. Since periphyton plays a great role for aquatic nutrient cycling, provides the basis for water purification, and can be regarded as a hotspot of microbial biodiversity, we highlight that more in-depth studies on microbial interactions in periphyton are needed to improve our understanding on functioning of freshwater ecosystems. In this paper we first present an overview on recent concepts (e.g., the “Black Queen Hypothesis”) derived from state-of-the-art OMICS methods including metagenomics, metatranscriptomics, and metabolomics. We then point to the avenues how these methods can be applied for future studies on biodiversity and the ecological role of freshwater periphyton, a yet largely neglected component of many freshwater ecosystems.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 969
Management of spionid mud worm infestations of Tasmanian cultured abalone
Creators: name: Lleonart, Mark
Publisher: name: University Of Tasmania
Year: 2023

description: Stock losses in the range 50-90% were recorded at experimental and pilot scale sea-based abalone farms in southern Tasmania in the mid-1990's. These were associated with spionid polychaete \mud worm\" infestation especially Boccardia knoxi. The overall aim of the multi faceted research presented here was to minimise the effects of spionid infestation. Studies of reproductive biology indicated initial infestation with B. knoxi could be delayed by placement of stock after the spring planktotrophic dispersal phase. This would also reduce infestation by a second species Polydora hoplura. Fieldwork during 1998-2001 indicated that large settlements of spionids might be relatively uncommon. Testing of 16 chemical/drug agents and freshwater bathing as a treatment for mud worm infestation failed to yield a useful candidate. Agents lacked penetration into shell burrows or were harmful to abalone at levels sufficient to kill spionids in situ. Air exposure of abalone for 2-4 hours at humidity less than approximately 63% was highly effective as a spionid treatment especially in the first 6 months post infestation. Assessment of risk factors associated with spionid settlement found that elevated levels of spirorbid polychaetes enhanced mud worm colonisation. Stock size rearing vessel design and position in the water column also led to differential spionid settlement outcomes. Spionid infestation was associated with a reduction in: growth % flesh weight protein and carbohydrate reserves and with an increased respiration rate. Major histological changes were elevated levels of brown pigment in the right kidney and digestive gland consistent with mobilisation and consumption of energy reserves. The ranges in levels of sodium potassium calcium magnesium chloride copper glucose and protein in haemolymph were established for apparently healthy abalone and spionid infested animals."
Dimensionally regularized Polyakov loop correlators in hot QCD
Creators: name: Burnier, Y.
name: Laine, M.
name: Vepsalainen, M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: A popular observable in finite-temperature lattice QCD is the so-called singlet quark-antiquark free energy, conventionally defined in Coulomb gauge. In an effort to interpret the existing numerical data on this observable, we compute it at order O(alpha_s^2) in continuum, and analyze the result at various distance scales. At short distances (r << 1/pi T) the behaviour matches that of the gauge-independent zero-temperature potential; on the other hand at large distances (r >> 1/pi T) the singlet free energy appears to have a gauge-fixing related power-law tail. At infinite distance the result again becomes physical in the sense that it goes over to a gauge-independent disconnected contribution, the square of the expectation value of the trace of the Polyakov loop; we recompute this quantity at O(alpha_s^2), finding for pure SU(Nc) a different non-logarithmic term than in previous literature, and adding for full QCD the quark contribution. We also discuss the value of the singlet free energy in a general covariant gauge, as well as the behaviour of the cyclic Wilson loop that is obtained if the singlet free energy is made gauge-independent by inserting straight spacelike Wilson lines into the observable. Comparisons with lattice data are carried out where possible.
description: 38 pages. v2: reference added, published version. v3: erratum added for sec.5, main results unchanged
Variable Sodium Absorption in a Low-Extinction Type Ia Supernova
Creators: name: Simon, Joshua D.
name: Gal-Yam, Avishay
name: Gnat, Orly
name: Quimby, Robert M.
name: Ganeshalingam, Mohan
name: Silverman, Jeffrey M.
name: Blondin, Stephane
name: Li, Weidong
name: Filippenko, Alexei V.
name: Wheeler, J. Craig
name: Kirshner, Robert P.
name: Patat, Ferdinando
name: Nugent, Peter
name: Foley, Ryan J.
name: Vogt, Steven S.
name: Butler, R. Paul
name: Peek, Kathryn M. G.
name: Rosolowsky, Erik
name: Herczeg, Gregory J.
name: Sauer, Daniel N.
name: Mazzali, Paolo A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Recent observations have revealed that some Type Ia supernovae exhibit narrow, time-variable Na I D absorption features. The origin of the absorbing material is controversial, but it may suggest the presence of circumstellar gas in the progenitor system prior to the explosion, with significant implications for the nature of the supernova progenitors. We present the third detection of such variable absorption, based on six epochs of high-resolution spectroscopy of the Type Ia supernova SN 2007le from Keck and the HET. The data span ~3 months, from 5 days before maximum light to 90 days after maximum. We find that one component of the Na D absorption lines strengthened significantly with time, indicating a total column density increase of ~2.5 x 10^12 cm^-2. The changes are most prominent after maximum light rather than at earlier times when the UV flux from the SN peaks. As with SN 2006X, we detect no change in the Ca II H&K lines over the same time period, rendering line-of-sight effects improbable and suggesting a circumstellar origin for the absorbing material. Unlike the previous two SNe exhibiting variable absorption, SN 2007le is not highly reddened (E_B-V = 0.27 mag), also pointing toward circumstellar rather than interstellar absorption. Photoionization models show that the data are consistent with a dense (10^7 cm^-3) cloud or clouds of gas located ~0.1 pc from the explosion. These results broadly support the single-degenerate scenario previously proposed to explain the variable absorption, with mass loss from a nondegenerate companion star responsible for providing the circumstellar gas. We also present tentative evidence for narrow Halpha emission associated with the SN, which will require followup observations at late times to confirm. [abridged]
description: 16 pages, 10 figures (8 in color), 5 tables. Accepted for publication in ApJ
Minerals, fatty acids, and antioxidant activity in sea knotgrass (Polygonum maritimum L.) seeds
Creators: name: Mahmoudi, Maher
name: Guemri, Ichraf
name: Boughalleb, Fayçal
name: Zaidi, Slah
name: Hessini, Kamel
name: Abdellaoui, Raoudha
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: The design of the current study was to determine the functional properties of P. maritimum seeds by evaluating their mineral content, fatty acid composition, and biactive compounds. Results showed that seeds contained remarkable amounts of Na, K, Ca, Mg, Cu, Zn, and Fe. The oil yield was found to be 4.58% and contained higher unsaturated fatty acids predominated by linoleic and oleic acids. The colorimetric investigation revealed high total polyphenol (33.56 mg gallic acid equivalent/g), flavonoid (46.3 mg quercetin equivalent/g), and condensed tannin (22.3 mg catechin equivalent/g) contents. Furthermore, the LC-ESI/MS analysis revealed the presence of 13 phenolics mostly predominated by (+) catechin, quercetin-3-O-galactoside, gallic acid, and quinic acid. The seeds possessed strong antioxidant potential evidenced by ABTS and DPPH radical scavenging activities, total antioxidant capacity, and reducing power. The present findings suggest that P. maritimum seeds may be used as a potential source of biologically active natural products.
Dihadron Azimuthal Correlation from Collins Effect in Unpolarized Hadron Collisions
Creators: name: Kang, Zhong-Bo
name: Yuan, Feng
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the dihadron azimuthal correlation produced nearly back-to-back in unpolarized hadron collisions, arising from the product of two Collins fragmentation functions. Using the latest Collins fragmentation functions extracted from the global analysis of available experimental data, we make predictions for the azimuthal correlation of two-pion production in $pp$ collisions at RHIC energies. We find that the correlation is sizable in the mid-rapidity region for moderate jet transverse momentum.
description: 13 pages, 3 figures
ВЛИЯНИЕ ХИМИЧЕСКОГО СОСТАВА НИЗКОЛЕГИРОВАННЫХ СТАЛЕЙ НА КРИТИЧЕСКУЮ ДЕФОРМАЦИЮ ДЛЯ ДИНАМИЧЕСКОЙ РЕКРИСТАЛЛИЗАЦИИ ПРИ ГОРЯЧЕЙ ТЕРМОМЕХАНИЧЕСКОЙ ОБРАБОТКЕ
Creators: name: КАЛИНИН АНТОН АЛЕКСЕЕВИЧ
name: КУТЕПОВ СЕРГЕЙ НИКОЛАЕВИЧ
name: ГВОЗДЕВ АЛЕКСАНДР ЕВГЕНЬЕВИЧ
name: СКРИПКИНА ЮЛИЯ ВЛАДИМИРОВНА
name: ШКАТОВ ВАЛЕРИЙ ВИКТОРОВИЧ
name: ГАДАЛОВ ВЛАДИМИР НИКОЛАЕВИЧ
Publisher: name: Известия Тульского государственного университета. Технические науки
Year: 2020
Subjects: ГОРЯЧАЯ ПРОКАТКА
ДИНАМИЧЕСКАЯ РЕКРИСТАЛЛИЗАЦИЯ
МЕТАДИНАМИЧЕСКАЯ РЕКРИСТАЛЛИЗАЦИЯ
КРИТИЧЕСКАЯ ДЕФОРМАЦИЯ
НИЗКОЛЕГИРОВАНННАЯ СТАЛЬ
ХИМИЧЕСКИЙ СОСТАВ
МОДЕЛЬ
КИНЕТИКА
СТАЛЬ 09Г2
ПРОГНОЗ
СТРУКТУРА ПРОКАТА
ТЕРМОМЕХАНИЧЕСКАЯ ДЕФОРМАЦИЯ
СТАНЫ ГОРЯЧЕЙ ПРОКАТКИ-СТАНЫ 2000
HOT ROLLING-RECRYSTALLIZATION
DYNAMIC RECRYSTALLIZATION
METADYNAMIC RECRYSTALLIZATION
CRITICAL DEFORMATION
LOW ALLOY STEEL
CHEMICAL COMPOSITION
MODEL
KINETICS
STEEL 09G2
FORECAST
ROLLED STRUCTURE
THERMOMECHANICAL DEFORMATION
HOT ROLLING MILLS 2000

description: Установлена зависимость критической деформации для динамической рекристаллизации в низколегированных сталях различного химического состава. Проанализирована усовершенствованная модель прогнозирования критической деформации при термомеханической рекристаллизации, оценивающая влияние химических компонентов сталей. Сделан анализ влияния химического состава сталей на величину критической деформации при термомеханической обработке. Установлено, что математическая модель может быть использована в системе автоматизированного управления структурой и свойствами сталей для прогноза условий развития динамической рекристаллизации и выбора оптимального химического и фазово-структурного состава сталей.
Induced p-wave superfluidity in two dimensions: Brane world in cold atoms and nonrelativistic defect CFTs
Creators: name: Nishida, Yusuke
Publisher: name: arXiv
Year: 2008
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: High Energy Physics - Theory (hep-th)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We propose to use a two-species Fermi gas with the interspecies s-wave Feshbach resonance to realize p-wave superfluidity in two dimensions. By confining one species of fermions in a two-dimensional plane immersed in the background three-dimensional Fermi sea of the other species, an attractive interaction is induced between two-dimensional fermions. We compute the pairing gap in the weak-coupling regime and show that it has the symmetry of p_x+ip_y. Because the magnitude of the pairing gap increases toward the unitarity limit, it is possible that the critical temperature for the p_x+ip_y-wave superfluidity becomes within experimental reach. The resulting system has a potential application to topological quantum computation using vortices with non-Abelian statistics. We also discuss aspects of our system in the unitarity limit as a "nonrelativistic defect conformal field theory (CFT)". The reduced Schrödinger algebra, operator-state correspondence, scaling dimensions of composite operators, and operator product expansions are investigated.
description: 22 pages, 10 figures; version to appear in Ann. Phys
Narlumosbart: First Approval
Creators: name: Dhillon, Sohita
Publisher: name: Adis Journals
Year: 2023
Subjects: Medicine

description: Declarations
Funding The preparation of this review was not supported by any external funding.
Authorship and Conflict of interest During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. Sohita Dhillon is a contracted employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to the review and are responsible for the article content.
Ethics approval, Consent to participate, Consent to publish, Availability of data and material, Code availability not applicable.
Additional information about this Adis Drug Review can be found here.
Abstract
Narlumosbart (津立生) is a recombinant, fully human, anti-receptor activator of nuclear factor kappa-Β ligand (RANKL) IgG4 monoclonal antibody being developed by CSPC Pharmaceutical and its wholly owned subsidiary Shanghai Jinmante Biotechnology for the treatment of giant cell tumour of bone (GCTB), bone metastases from solid tumours and osteoporosis. The RANK/RANKL signalling pathway plays a pivotal role in osteoclastogenesis and in the pathogenesis of GCTB. Narlumosbart specifically binds to RANKL and blocks the interaction of RANKL with RANK, thus inhibiting osteoclastogenesis and bone resorption by osteoclasts. In September 2023, narlumosbart received conditional first approval in China for the treatment of adults with GCTB that is unresectable or when surgical resection would result in severe functional disability. Clinical studies of narlumosbart for bone metastases, postmenopausal osteoporosis and glucocorticoid-induced osteoporosis are underway in China. This article summarizes the milestones in the development of narlumosbart leading to this first approval for the treatment of adults with GCTB.
© Springer Nature Switzerland AG 2023
Two new octahydronaphthalene derivatives, trichodermic acids C and D produced by Trichoderma sp. HN-1.1
Creators: name: Sofian, Ferry Ferdiansyah
name: Warahapsari, Fatimah Ayu
name: Yoshida, Jun
name: Ito, Yoshiaki
name: Koseki, Takuya
name: Shiono, Yoshihito
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Two new octahydronaphthalene derivatives, trichodermic acid C (1) and trichodermic acid D (2), along with known analogs, trichodermic acid (3), trichodermic acid A (4) and trichodermic acid B (5), were isolated from an ethyl acetate extract of endophytic strain Trichoderma sp. HN-1.1. The structures of compounds 1 and 2 were elucidated using spectroscopic methods including UV, IR, HRESITOFMS, ECD, 1 D and 2 D NMR. The cytotoxic activity of the isolated compounds was evaluated on the rat hepatoma cell line H4IIE, using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. According to the results, only compound 3 showed a significant reduction of H4IIE cells from 75 to 21% (p 50 value of 50% cell survival estimated as 143.1 µM, which indicated weak cytotoxic activity.
Quantitative genetics and breeding of Eucalyptus globulus
Creators: name: Lopez, GA
Publisher: name: University Of Tasmania
Year: 2023

description: This thesis studies quantitative genetic variation in the forest tree, Eucalyptus globulus. It examines the effects of inbreeding and hybridisation on fitness, as well as genetic variation in breeding traits using an extensive base population and a diallel of intra- and inter-race reciprocal crosses. Marked post-zygotic barriers to hybridisation occurred between E. globulus and E. ovata, with F\\(_1\\) hybrids exhibiting high field mortality. Inbreeding similarly had deleterious effects, but by 10 years F\\(_1\\) survival was less than the selfs. Relative hybrid fitness is dependent on inbreeding levels of parental population. Open-pollinated (OP) progenies also exhibited growth depression compared with outcrosses, clearly indicating significant inbreeding is occurring under this mating system. Genetic variation was examined in a base population of E. globulus established on four sites in Argentina. This population included OP progenies from native stands and land races. Thirty variables were studied, representing growth, bark thickness, form, transition to adult foliage and Pilodyn penetration, and used to determine population affinities. Significant genetic differentiation occurred between populations in most traits. Land races had closer affinities to native stands from southern Tasmania. Many native populations were superior in growth to land races, but land races had better form. Significant genetic variation was also detected within E. globulus populations. Heritabilities were low for forking, survival and form; intermediate for growth and bark thickness; and high for Pilodyn penetration and transition to adult foliage. There was strong positive genetic correlation between the same trait measured at different sites and ages. Growth traits were genetically independent from other key breeding traits. Genetic parameter estimates from OP progenies may be biased by inbreeding depression, as well as specific combining (SCA), maternal and carry-over effects. The effects of such factors on growth were examined using a diallel mating amongst eight trees from two E. globulus races. Rapid germination and large seeds resulted in larger seedlings in the nursery, but these carry-over effects disappeared after two-years field growth at two Tasmanian sites. Additive and SCA effects were insignificant at this age, but the interaction between males and females was significant, with reciprocal inter-race hybrids differing in performance. Parents differed in chloroplast haplotypes and this is the first evidence for cyto-nuclear interactions affecting growth of a eucalypt species. Such reciprocal effects could bias genetic parameters and mean the cross direction may be important to maximise gains from mass controlled pollinated seed production systems being developed.
Guidelines for reporting the use of gel electrophoresis in proteomics
Creators: name: Gibson, Frank
name: Anderson, Leigh
name: Babnigg, Gyorgy
name: Baker, Mark
name: Berth, Matthias
name: Binz, Pierre-Alain
name: Borthwick, Andy
name: Cash, Phil
name: Day, Billy W
name: Friedman, David B
name: Garland, Donita
name: Gutstein, Howard B
name: Hoogland, Christine
name: Jones, Neil A
name: Khan, Alamgir
name: Klose, Joachim
name: Lamond, Angus I
name: Lemkin, Peter F
name: Lilley, Kathryn S
name: Minden, Jonathan
name: Morris, Nicholas J
name: Paton, Norman W
name: Pisano, Michael R
name: Prime, John E
name: Rabilloud, Thierry
name: Stead, David A
name: Taylor, Chris F
name: Voshol, Hans
name: Wipat, Anil
name: Jones, Andrew R
Publisher: name: arXiv
Year: 2009
Subjects: subject: Genomics (q-bio.GN)
subject: FOS: Biological sciences

description: the MIAPE Gel Electrophoresis (MIAPE-GE) guidelines specify the minimum information that should be provided when reporting the use of n-dimensional gel electrophoresis in a proteomics experiment. Developed through a joint effort between the gel-based analysis working group of the Human Proteome Organisation's Proteomics Standards Initiative (HUPO-PSI; http://www.psidev.info/) and the wider proteomics community, they constitute one part of the overall Minimum Information about a Proteomics Experiment (MIAPE) documentation system published last August in Nature Biotechnology
Worry in children : interpretations of hypothetical scenarios and the relationship to parent factors
Creators: name: Mason, Bronte
Publisher: name: University Of Tasmania
Year: 2023

description: Worry is a commonly experienced phenomenon that serves the important cognitive function of preparing the individual to anticipate future threats. Perceived benefits of worry include enhancement of motivation and facilitation of preparatory and analytical thinking, each of which can facilitate problem-solving. At the pathological extreme, worry is associated with problem exacerbation and increases in anxiety, and excessive worry is the key diagnostic feature of generalised anxiety disorder (GAD). Hitherto, relatively little research has investigated worry in child and adolescent populations. The literature thus far suggests that worry in children is common, with excessive worry also being documented. Studies suggest that the content of children's worry is predominantly self-referent, focusing on issues such as school, personal harm and health (e.g., Silverman, LaGreca, & Wasserstein, 1995). However, other research suggests a shift for children's worry concerns to focus on broader societal and environmental issues such as pollution, starvation and nuclear war (e.g., Gottlieb & Bronstein, 1996). Age differences and sex differences in content and prevalence of worry have also been noted. The literature suggests that several cognitive biases are characteristic of highly anxious individuals. These include sensitivity to threat cues, a tendency to interpret ambiguous cues as threatening and a tendency to overestimate the likelihood of threat. Several studies have replicated these findings in high worry populations, but research using child worriers is particularly limited. The literature has also explored the role of family factors on the development and maintenance of anxiety in children. Parenting styles characterised by overprotection and lack of warmth have been particularly implicated as contributing to anxiety in children. Again, further research is required to evaluate the role of family processes on the development and maintenance of worry in children.
Coherent and incoherent space charge resonance effects
Creators: name: Hofmann, I.
Publisher: name: CERN Yellow Reports: Conference Proceedings
Year: 2020

description: The question of interplay of coherent and incoherent space charge driven resonances and of their Landau damping has found some interest in beam dynamics of modern high-intensity synchrotrons. We revisit the theoretical and simulation models describing coherent half-integer parametric resonances, analyze their Landau damping in 2D beams on the basis of simulated tune spectra and conclude that above second order (envelope modes) they play no role in realistic, Gaussian-like beam models. We also analyze incoherent resonance effects in the beam core regions and find that their role has been underestimated in part of the literature, in particular with regard to the very long-term beam evolution as in synchrotrons. We conclude that for such time scales more careful analysis of realistic simulation models is needed to support synchrotron design and evaluation of experiments.
description: CERN Yellow Reports: Conference Proceedings, Vol. 9 (2020): Proceedings of the ICFA mini-Workshop on Mitigation of Coherent Beam Instabilities in Particle Accelerators, Zermatt, Switzerland, 23–27 September 2019
Additional file 6 of MiR-425-5p accelerated the proliferation, migration, and invasion of ovarian cancer cells via targeting AFF4
Creators: name: Wu, Zhihui
name: Guo, Jianlin
name: Zhang, Ying
name: Liu, Jianhua
name: Ma, Hongping
name: Tang, Yurong
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology

description: Additional file 6: Table S1. Sequences of miR-425-5p mimic, miR-425-5p inhibitor, and sh-AFF4 that were used in the study.
The Growth of Black Holes: Insights From Obscured Active Galaxies
Creators: name: Greene, Jenny E.
name: Zakamska, Nadia L.
name: Liu, Xin
name: Barth, Aaron J.
name: Ho, Luis C.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Obscured or narrow-line active galaxies offer an unobstructed view of the quasar environment in the presence of a luminous and vigorously accreting black hole. We exploit the large new sample of optically selected luminous narrow-line active galaxies from the Sloan Digital Sky Survey at redshifts 0.1 < z < 0.45, in conjunction with follow-up observations with the Low Dispersion Survey Spectrograph (LDSS3) at Magellan, to study the distributions of black hole mass and host galaxy properties in these extreme objects. We find a narrow range in black hole mass ( = 8.0 +/- 0.7) and Eddington ratio ( = -0.7 +/- 0.7) for the sample as a whole, surprisingly similar to comparable broad-line systems. In contrast, we infer a wide range in star formation properties and host morphologies for the sample, from disk-dominated to elliptical galaxies. Nearly one-quarter have highly disturbed morphologies indicative of ongoing mergers. Unlike the black holes, which are apparently experiencing significant growth, the galaxies appear to have formed the bulk of their stars at a previous epoch. On the other hand, it is clear from the lack of correlation between gaseous and stellar velocity dispersions in these systems that the host galaxy interstellar medium is far from being in virial equilibrium with the stars. While our findings cast strong doubt on the reliability of substituting gas for stellar dispersions in high luminosity active galaxies, they do provide direct evidence that luminous accreting black holes influence their surroundings on a galaxy-wide scale.
description: Accepted for publication in ApJ, 19 pages, 9 figures
Feedback design for control of the micro-bunching instability based on reinforcement learning
Creators: name: Boltz, T.
name: Brosi, M.
name: Bründermann, E.
name: Haerer, B.
name: Kaiser, P.
name: Pohl, C.
name: Schreiber, P.
name: Yan, M.
name: Asfour, T.
name: Müller, A.-S.
Publisher: name: CERN Yellow Reports: Conference Proceedings
Year: 2020

description: The operation of ring-based synchrotron light sources with short electron bunches increases the emission of coherent synchrotron radiation in the THz frequency range. However, the micro-bunching instability resulting from self-interaction of the bunch with its own radiation field limits stable operation with constant intensity of CSR emission to a particular threshold current. Above this threshold, the longitudinal charge distribution and thus the emitted radiation vary rapidly and continuously. Therefore, a fast and adaptive feedback system is the appropriate approach to stabilize the dynamics and to overcome the limitations given by the instability. In this contribution, we discuss first efforts towards a longitudinal feedback design that acts on the RF system of the KIT storage ring KARA (Karlsruhe Research Accelerator) and aims for stabilization of the emitted THz radiation. Our approach is based on methods of adaptive control that were developed in the field of reinforcement learning and have seen great success in other fields of research over the past decade. We motivate this particular approach and comment on different aspects of its implementation.
description: CERN Yellow Reports: Conference Proceedings, Vol. 9 (2020): Proceedings of the ICFA mini-Workshop on Mitigation of Coherent Beam Instabilities in Particle Accelerators, Zermatt, Switzerland, 23–27 September 2019
Sustainable Synthesis of Bio-based Recyclable Thermosets
Creators: name: Löser, Pia Simone
Publisher: name: Karlsruhe
Year: 2020
Subjects: Green chemistry
bio-based
polymers
recyclability

description: In den letzten Jahren hat sich die Polymerforschung zunehmend um nachhaltige Alternativen zu den etablierten erdölbasierten Polymeren bemüht, sodass sich dieses Forschungsgebiet zu einem wichtigen Teilbereich der Polymerchemie entwickelt hat. Sowohl die Verknappung von fossilen Rohstoffen, als auch zunehmende ökologische Bedenken erfordern einen Wandel bei den Produktionsmethoden und der Rohstoffbasis. Dies gilt auch für duroplastische Kunststoffe. Der Fokus dieser Arbeit liegt daher auf der nachhaltigen Synthese biobasierter Monomere für die Herstellung von Duroplasten. Im ersten Teil der Arbeit wurde Vanillylalkohol als nachwachsender Rohstoff für die Monomersynthese untersucht. Zunächst wurde dieser durch Allylierung mit Allyl methyl carbonat und anschließende Epoxidierung der eingeführten Doppelbindung modifiziert. Um eine Rezyklierbarkeit des Materials zu erreichen, wurde der modifizierte Vanillylalkohol im nächsten Schritt zu symmetrischen Dimeren gekuppelt, wobei spaltbare Linkergruppen eingeführt wurden. Dabei wurden säurelabile Bisallylether und Bisepoxide erhalten. Im zweiten Teil der Arbeit wurden Terpene als nachwachsender Rohstoff für die Synthese biobasierter Amine als Härter für Epoxidharze untersucht. Dafür wurde ein Syntheseweg beginnend mit einer Epoxidierung der vorhandenen Doppelbindungen mit anschließender Umlagerung zu Biscarbonylen etabliert. Durch eine anschließende reduktive Aminierung können Diamine synthetisiert werden. Zunächst wurden verschiedene Epoxidierungsmethoden untersucht. Anschließend wurde die Umlagerung zu den entsprechenden Carbonylen optimiert, wobei sich Bismuth triflat als effizienter Katalysator für verschiedene Substrate erwies. Da sich die anschließende reduktive Aminierung der Biscarbonyle als schwierig herausstellte, wurden die Diamine über einen alternativen Syntheseweg durch Ringöffnung von biobasierten Epoxiden mit Ammoniak hergestellt. Im dritten Teil der Arbeit wurden die abbaubaren Bisallylether, die auf Basis von Vanillylalkohol synthetisiert worden waren, für Thiol-en Polymerisationen verwendet. Eine genaue Untersuchung der thermomechanischen Eigenschaften der erhaltenen Polymerfilme ermöglichte die Identifizierung geeigneter Monomere für den potentiellen Ersatz erdölbasierter Produkte. Des Weiteren wurden die gekuppelten bisfunktionellen Epoxide zusammen mit den zuvor hergestellten Amin-Härtern für den Einsatz in Epoxidharzen untersucht. Über die Materialeigenschaften der erhaltenen Harze konnte die Eignung der einzelnen Monomere für die Synthese von Duroplasten beurteilt werden. Schließlich wurden im letzten Teil der Arbeit verschiedene Reaktionsbedingungen für die kontrollierte Zersetzung der hergestellten vernetzten Polymere getestet. Zunächst wurde der Abbau an den Monomeren optimiert. Im Folgenden wurden die besten Bedingungen dann auf einen der synthetisieren Polymerfilme übertragen, um die Abbaubarkeit der Polymere zu demonstrieren.