cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
[Wappen mit einem Raben]
Creators: name: Glasmaleratelier Röttinger
Publisher: name: [Glasmaleratelier Röttinger]
Year: 1887
Subjects: Rabe
Wappenschild

description: Rabe auf Dreiberg
description: Der unsignierte Scheibenriss einer Wappenscheibe stammt aus der Werkstatt Röttinger
description: Aus dem Nachlass der Familie Röttinger Exemplar der Zentralbibliothek Zürich, Graphische Sammlung und Fotoarchiv
Additional file 1 of Associations of different types of physical activity and sedentary behavior with self-rated health in children and adolescents: a systematic review of research from 2010 to 2024
Creators: name: Liang, Yahan
name: Zhu, Xihe
name: Yang, Ji-Hye
name: Wang, Fei
name: Zhang, Danqing
name: Yang, Xingyi
name: Chen, Sitong
name: Liu, Yang
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1.
Der  Tempel der Unschuld
Creators: name: Götz, Gottfried Bernhard
Publisher: name: [s.n.]
Year: 1753

description: G. B. Göz fecit A.V.
description: Druckplatte für das Neujahrsblatt / hrsg. von der Stadtbibliothek Zürich auf 1753 (damals Bürgerbibliothek)
description: Unten spiegelverkehrt bezeichnet: "Der Tugend und kunstliebenden Jugend von der Bürger Bibliothec in Zürich Verehrt, beym Neuen Jahr 1753"
description: Vergleiche das gedruckte Blatt, Signatur: ZB-AZZ 17:112, Systemnummer: 005407243
Pennalithus palgongensis
Creators: name: Mu, Yannan
name: Zhang, Feng
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Phrurolithidae
Pennalithus
Pennalithus palgongensis

description: Pennalithus palgongensis (Seo, 1988) (ĀẄŢRff)
Figs 64–66
Phrurolithus palgongensis Seo, 1988 a: 83, figs 27–32.
Phrurolithus liaoningensis Song et al., 1994: 169, figs 1–5.
Otacilia palgongensis Zamani & Marusik, 2020: 312.
Pennalithus palgongensis Kamura, 2021: 125.
For complete bibliography see World Spider Catalog (2023).
Material examined. 1 ♀, CHINA: Liaoning Province: Dalian City, Zhuanghe County, Xianren Cave Conservation Area (40°00.655′N, 122°58.262′E, 143 m a.s.l.), 4 Jul. 2016, leg. Weitong Wang; 1 ♀, Jilin Province: Tonghua City, Ji’an County, Dalu Town (40°59.591′N, 125°46.597′E, 239 m a.s.l.), 9 Jul. 2016, leg. Weitong Wang.
Diagnosis. See Kamura, 2021.
Description. See Kim & Lee, 2014. Habitus and genitalia as in Figs 64–65.
Distribution. China (Jilin Province, Liaoning Province).
Remark. This species is recorded from Jilin province for the first time.
description: Published as part of Mu, Yannan & Zhang, Feng, 2023, Further additions to the guardstone spider fauna from China (Araneae: Phrurolithidae), pp. 1-104 in Zootaxa 5338 (1) on page 78, DOI: 10.11646/zootaxa.5338.1.1, http://zenodo.org/record/8283738
Additional file 1 of Calpain inhibition as a novel therapeutic strategy for aortic dissection with acute lower extremity ischemia
Creators: name: Tan, Qiwen
name: Wang, Xiaokang
name: Xu, Wanchuang
name: Song, Kun
name: Xiong, Yifan
name: Jiang, Zhentong
name: Li, Jingjing
name: Yu, Yunsheng
name: Ye, Wenxue
name: Shen, Zhenya
name: Teng, Xiaomei
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: Virology

description: Supplementary Material 1
Der  Junge Gelehrte
Creators: name: Füssli, Johann Rudolf
name: Gellert, Christian Fürchtegott
Publisher: name: [s.n.]
Year: 1756
Subjects: Allegorie
Hohes Alter
Jugend

description: Joh. Rudolf Füessli fec.
description: Druckplatte für das Neujahrsblatt / hrsg. von der Stadtbibliothek Zürich auf 1756 (damals Bürgerbibliothek)
description: Unten spiegelverkehrt bezeichnet: "Der Tugend und Kunst liebenden Jugend von der Burger Bibliothec in Zürich geschenket beim Neüen Jahr 1756"
description: Vergleiche das gedruckte Blatt, Signatur: ZB-AZZ 17:115, Systemnummer: 005407924
description: Vergleiche die Vorzeichnung, Signatur: ZB-ZEI_Njbl. 35, Systemnummer: 005564457
[Helfer v. Orelli-Escher]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1850

description: Der Dargestellte konnte nicht individualisiert werden. Auf Unterlage mit Bleistift bezeichnet "Helfer v. Orelli-Escher" [Diakon v. Orelli-Escher]
description: Anonyme Fotografie
โครงการเพื่อบรรเทาผลกระทบทางสังคมเนื่องจากวิกฤตการณ์เศรษฐกิจ
Creators: name: Potter, Jack M
Publisher: name: University of Chicago Press
Year: 1976
Subjects: Peasantry
Family
Ethnology

description: Journal of Population and Social Studies, 12, 1, 14
The 2014 “Humanitarian Situation”: The Portrayal of Central American Migrant Minors in the Mexican Press
Creators: name: Acuña Lacarieri, Estefanía
Publisher: name: Stanford Digital Repository
Year: 2024
Subjects: subject: Migrant minors
subject: Media framing theory
subject: Central America
subject: Mexico
subject: Mexican Press
subject: Migration policy
subject: Political Science
subject: FOS: Political science
subject: History
subject: Communication

description: In 2014, an unprecedented number of children fled violence from Honduras, El Salvador, and Guatemala, crossing Mexico’s southern border in search of better opportunities in the United States. On June 2, 2014, a presidential memorandum by Barack Obama described the arrival of Central American minors as an “urgent humanitarian situation,” bringing the matter to public and political attention. Drawing from a content analysis of 50 news articles published by El Universal and Reforma in 2014, this study revealed that the Mexican press’ coverage of Central American minors shifted after the issue garnered political attention. In the latter half of 2014, the Mexican press published a greater number of articles about their arrival, increased the word count of stories about minors, and included other stakeholders in the debate, such as human rights activists. Given the increased presence of human rights representatives in the coverage, the tone toward migrant minors was slightly more positive after June. Articles were also analyzed using the media framing theory. Results showed that the Mexican press focused on those responsible for addressing the situation, such as government officials, and highlighted conflict between different sides of the public debate. In doing so, the press left migrant minors, the main stakeholders affected by these policies and public debates, in the background, as a nameless and voiceless mass. This study, therefore, makes a call for nuanced representations of Central American migrant minors to humanize their stories in the Mexican press.
Additional file 1 of Mannose and PMI depletion overcomes radiation resistance in HPV-negative head and neck cancer
Creators: name: Wang, Tongchuan
name: Brown, Connor
name: Doherty, Niamh
name: Byrne, Niall M.
name: Islam, Rayhanul
name: Doherty, Meabh
name: Feng, Jie
name: Yin, Cancan
name: Chambers, Sarah
name: McQuoid, Lydia
name: Mohamed-Smith, Letitia
name: Butterworth, Karl T.
name: Kerr, Emma M.
name: Coulter, Jonathan A.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
"Erinnerungen in der Neujahrsnacht 1867. Den drei Züricher Freunden". Gedicht von Karl Joh. Aug. Theodor Scheerer (1813-1875)
Creators: name: Scheerer, Karl Joh. Aug. Theodor
Publisher: name: [s.n.]
Year: 1867

description: Reinschrift eines Gedichts von Karl Joh. Aug. Theodor Scheerer an seine Freunde Arnold Escher von Linth, Stockar und David Friedrich Wiser
description: ETH-Bibliothek
Additional file 2 of Mannose and PMI depletion overcomes radiation resistance in HPV-negative head and neck cancer
Creators: name: Wang, Tongchuan
name: Brown, Connor
name: Doherty, Niamh
name: Byrne, Niall M.
name: Islam, Rayhanul
name: Doherty, Meabh
name: Feng, Jie
name: Yin, Cancan
name: Chambers, Sarah
name: McQuoid, Lydia
name: Mohamed-Smith, Letitia
name: Butterworth, Karl T.
name: Kerr, Emma M.
name: Coulter, Jonathan A.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
Die  Gärtnerin und die Biene
Creators: name: Füssli, Johann Rudolf
Publisher: name: [s.n.]
Year: 1757
Subjects: Bienenstock
Gärtnerin

description: J. R. F. f.
description: Druckplatte für das Neujahrsblatt / hrsg. von der Stadtbibliothek Zürich auf 1757 (damals Bürgerbibliothek)
description: Unten spiegelverkehrt bezeichnet: "Der Tugend und Kunst-liebenden Jugend, von der burger Bibliothec in Zürich geschenkt beim Neü Jahr 1757"
description: Vergleiche das gedruckte Blatt, Signatur: ZB-AZZ 17:116, Systemnummer: 005407939
Xilithus Liu & Li 2022
Creators: name: Mu, Yannan
name: Zhang, Feng
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Phrurolithidae
Xilithus

description: Xilithus Liu & Li, 2022
Xilithus Lin, Li & Pham, 2023: 57
(type species: Acrolithus lingyun Liu & Li, 2022, by original designation).
Acrolithus Liu et al., 2022: 5 (preoccupied).
Diagnosis. This genus can be distinguished from all other phrurolithid genera by the male palpal tegulum with a spiculate prolateral tegular apophysis and long, needle-like embolus; it can also be identified by the dark, slanted male palpal bulb with a nearly round distal tegular apophysis. Female epigynal plate with a pair of large shallow concavities.
Description. Medium-sized spiders. Carapace oval, dark brown, highest near fovea, with several distinct markings resembling flowing water droplets beside fovea. Chelicerae with two spines anteriorly (one long and another short). Femora I–IV with one dorsal spine, femur I with three to four prolateral spines, femur II with one or two prolateral spines; tibia I usually with seven pairs of ventral spines, tibia II usually with six pairs of ventral spines; metatarsus I usually with four pairs of ventral spines, metatarsus II usually with four proventral spines and three retroventral spines. Abdomen oval, with large dorsal scutum nearly covering entire abdomen in males. Male palp: femoral apophysis well developed; tibia with one retrolateral tibial apophysis and one small retroventral tibial apophysis (absent in some species); tegulum wider than cymbium, with spiculate prolateral tegular apophysis; embolus long, needle-like. Female epigyne: epigynal plate with median septum and pair of large shallow concavities; copulatory ducts longer than connecting tubes; glandular appendages digitiform or mastoid-shaped; spermathecae small and round.
description: Published as part of Mu, Yannan & Zhang, Feng, 2023, Further additions to the guardstone spider fauna from China (Araneae: Phrurolithidae), pp. 1-104 in Zootaxa 5338 (1) on pages 92-93, DOI: 10.11646/zootaxa.5338.1.1, http://zenodo.org/record/8283738
Xilithus pugious, sp. nov.
Creators: name: Mu, Yannan
name: Zhang, Feng
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Phrurolithidae
Xilithus
Xilithus pugious

description: Xilithus pugious sp. nov. (Ŀẇdzff)
Figs 79–81
Type material. Holotype ♁, CHINA: Zhejiang Province: Lishui City, Longquan County, Fengyang Mountain National Nature Reserve (27°52′49.46″N, 119°10′10.76″E, 1494 m a.s.l.), 29 Apr. 2016, leg. Yannan Mu.
Etymology. This specific name is derived from the Latin word “ pugio ”, referring to the dagger-shaped prolateral tegular apophysis; adjective.
Diagnosis. This new species resembles X. shijiao Liu & Li, 2022 in having a similar embolus shape, but can be recognized by: 1) the wider, shorter and dagger-shaped prolateral tegular apophysis (vs thin and long, cf. Fig. 80C and fig. 9G in Liu et al. [2022]), 2) claviform retroventral tibial apophysis with compressed tip (vs cylindrical tip, cf. Fig. 80E and fig. 9I in Liu et al. [2022]), 3) retrolateral tibial apophysis bifurcate, with the short branch nearly triangular (vs short branch almost rectangular, cf. Fig. 80D and fig. 9I in Liu et al. [2022]).
Description. Male (Holotype): total length 3.58, carapace 1.82 long, 1.57 wide; abdomen 1.76 long, 1.27 wide. Eye sizes and interdistances: AME 0.11, ALE 0.14, PME 0.10, PLE 0.10; AME–AME 0.04, AME–ALE 0.02, ALE– ALE 0.28, PME–PME 0.09, PME–PLE 0.08, PLE–PLE 0.44, ALE–PLE 0.07. EAW 0.59, CRW 0.83, EAW/CRW 0.71, CRW/CW 0.53. MOA 0.26 long, anterior width 0.26, posterior width 0.29. CH 0.19, CH /AME 1.73. Labium 0.24 long, 0.27 wide. Sternum 1.00 long, 0.94 wide. Leg measurements: Ⅰ 6.36 (1.75, 0.60, 1.69, 1.46, 0.86), II 5.61 (1.47, 0.56, 1.40, 1.30, 0.88), III 4.95 (1.36, 0.54, 1.01, 1.25, 0.79), IV 7.06 (1.86, 0.63, 1.66, 1.94, 0.97). Spination: femora I–IV d 1, femur Ⅰ pl 4, tibia Ⅰ pv 7 rv 7, tibia II pv 6 rv 6, metatarsus Ⅰ pv 4 rv 4, metatarsus II pv 4 rv 3.
Coloration. Carapace nearly round, red-brown, with several markings resembling flowing water droplets beside fovea. Abdomen lighter in color than carapace, with large dorsal scutum covering almost entire abdomen, with indistinct light triangular marking anteriorly (Fig. 79). Legs brown.
Palp as in Figs 80–81. Femur apophysis large, well-developed, located near middle. Retroventral tibial apophysis extending towards retrolateral side, with wide base and compressed tip. Retrolateral tibial apophysis with wide base, tip bifurcated with two branches, long branch lamelliform, curved towards cymbium, short branch nearly triangular. Tegulum wider than cymbium, pyriform; tegular apophysis absent. Sperm duct distinct, tapering from retrolateral side of tegulum to embolus. Embolus long, needle-like, slanting upwards. Conductor absent.
Female: unknown.
Distribution. China (Zhejiang Province).
description: Published as part of Mu, Yannan & Zhang, Feng, 2023, Further additions to the guardstone spider fauna from China (Araneae: Phrurolithidae), pp. 1-104 in Zootaxa 5338 (1) on pages 93-95, DOI: 10.11646/zootaxa.5338.1.1, http://zenodo.org/record/8283738
Wind Systems and Energy Balance in the Dead Sea Valley
Creators: name: Metzger, Jutta
Publisher: name: KIT Scientific Publishing
Year: 2017
Subjects: Verdunstung
Energiebilanz
periodische Windsysteme
Messungen
Evaporation
Energy Balance
Periodic Wind Systems
Measurements

description: A new measurement concept was developed to determine the amount, variability and governing factors of evaporation from the Dead Sea. Additionally, a suitable indirect method to calculate evaporation is presented. Results show that vapour pressure deficit and wind speed are governing evaporation and that the diurnal cycle is determined by three distinct diurnal wind systems. The occurrence frequency and intensity of the wind systems are determined by local differential cooling and heating.
Xilithus xiaojing Liu & Li 2022
Creators: name: Mu, Yannan
name: Zhang, Feng
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Phrurolithidae
Xilithus
Xilithus xiaojing

description: Xilithus xiaojing Liu & Li, 2022 (ṁĦẇdzff)
Figs 85–86
Acrolithus xiaojing Liu & Li, 2022: 354, Suppl. 2: 15, figs 14A–F, 15A–H, 16A–D, 20E.
Xilithus xiaojing Lin, Li & Pham, 2023: 57.
Material examined. 1 ♁ 2♀, CHINA: Hunan Province: Chenzhou City, Rucheng County, Jiulongjiang National Forest Park, Qinglong Gorge Scenic Spot (25.394029°N, 113.785765°E, 300 m a.s.l.), 12 May 2018, leg. Yannan Mu.
Diagnosis. See Liu et al. 2022a.
Description. See Liu et al. 2022a. Habitus and genitalia in Figs 85–86.
Distribution. China (Hunan and Jiangxi provinces).
Remark. This species is recorded from Hunan Province for the first time.
description: Published as part of Mu, Yannan & Zhang, Feng, 2023, Further additions to the guardstone spider fauna from China (Araneae: Phrurolithidae), pp. 1-104 in Zootaxa 5338 (1) on pages 100-101, DOI: 10.11646/zootaxa.5338.1.1, http://zenodo.org/record/8283738
title: Designing the streets of the future: The Avenues Programme, Glasgow
Creators: name: Cox, Becki
Publisher: name: University of Glasgow
Year: 2024

description: There is a pressing need to transition urban areas towards a more sustainable way of life, but the scale of the challenge is significant. Streets are the foundation of a city’s urban fabric and play a critical role in the transition to urban sustainability. The aim of this research was to investigate the processes taking place during the conceptualisation and design of a contemporary street, and to examine what the implications of these processes are for longer-term transitional change. The thesis makes theoretical contributions to the transitions and urban design governance literature, as well as methodological and practice-oriented contributions in the form of a novel analytical framework for the design and analysis of mixed-use streets of the future. The focus of this research was the Avenues Programme in Glasgow: a transformative investment programme seeking to regenerate a network of streets across the city centre. The pilot project was completed in 2019 on Sauchiehall Street, a busy, mixed-use retail street and movement corridor. Sauchiehall Street thus offered an ideal location to examine how the process of conceptualising and designing a street can shape the infrastructure that is constructed, then in turn how the design of the infrastructure can shape the instinctive behaviour of those using it. This research takes the form of a mixed methods case study. An initial process (qualitative) phase comprised document analysis and semi-structured ‘elite’ interviews. This was followed by an observational (quantitative and qualitative) phase capturing instinctive behaviour at key pieces of street infrastructure. The creation of a novel analytical framework, an original contribution based on socio-technical transition theory, provides the means to analyse not just how this particular street is functioning, but the implications of street design more broadly for enabling behavioural transitions in the future. This thesis argues that contemporary mixed-use streets are key to bringing about sustainable urban transitions but that to do this, they must be designed to enable not just ‘place’ and ‘movement’, but also thriving public life. Creating these streets of the future requires those entrusted with the design and construction of them to be ‘knowing’ and aware of their disciplinary biases. A regeneration ‘champion’ can be instrumental in ensuring effective urban design governance, but urban design and engineering must be properly integrated in conceptual and written form to ensure that infrastructure design is not inadvertently undermined.
Does Say-on-Pay (SoP) Affect CEO Compensation Following an M&A Deal?
Creators: name: Chen, Shuyang
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2018
Subjects: Say-on-Pay
CEO Compensation
M&A Deal

description: This study examines the effectiveness of Say on Pay (SoP) regulation as a corporate governance mechanism in the context of M&A deals. Using a large sample of U.S. firms over the 2005-2017 period, this study finds that, in the post-SoP period, overall CEO pay growth rate declines and CEO pay to acquisition performance sensitivity improves following M&A activities. This supports ‘SoP governance’ hypothesis, which proposes that SoP regulation will restrict CEOs self-fulfilling behaviour. In a macro-economic set-up, the introduction of SoP regulation was intended to discipline top managers by giving shareholders an opportunity to express their opinion on CEO compensation. It was therefore expected that, in the post SoP-era, CEOs will experience a lower growth in their pay package following M&A deals. On the other hand, the relation between SOP voting approval rates and CEO compensation following M&A activities is unidirectional. Irrespective of the performance of M&A deals, it is observed that CEOs with higher shareholder voting approval experience a significant positive change in their compensation level after an M&A deal. We term this as a ‘reliable CEO’ hypothesis. According to the ‘reliable CEO hypothesis, a very high voting percentage may legitimize CEOs action and embolden CEOs to carry out more risky ventures such as M&As. Since there is an established relation between risk and return, shareholders would like CEOs to take appropriate risks to increase firm value. A reliable CEO, who enjoys a high degree of shareholders’ support, should not be penalized for taking more risky ventures that are intended to increase shareholders’ wealth. Our results confirm this viewpoint.
"Zu Neujahr 1866". Gedicht von Karl Joh. Aug. Theodor Scheerer (1813-1875), aufbewahrt im Nachlass von Arnold Escher von der Linth (1807-1872)
Creators: name: Scheerer, Karl Joh. Aug. Theodor
Publisher: name: [s.n.]
Year: 1865

description: Gedrucktes Gedicht von Karl Joh. Aug. Theodor Scheerer
description: ETH-Bibliothek
The Role of Blood Viscosity in the Development of Metastasis
Creators: name: Ramakrishnan, Karthik
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Cancer is a heterogeneous class of diseases characterized by the uncontrolled growth of cells within the human body. Solid tumors may invade nearby tissues and eventually enter the bloodstream and travel throughout the body. Cancer is divided into four stages that describe the degree to which cancer cells have invaded tissue and spread throughout the body. Stage IV, metastatic disease, is the most invasive stage in which cancer cells have spread from the primary tumor to distant organs in a process known as metastasis. One major way in which cancer cells are able to do this is by transport through the circulatory system. As such, defining how the fluid dynamics of blood flow influence cancer cells is a key component of studying this process. The goal for this project is to explore the impact of blood viscosity (thickness) on the process of metastasis. Currently, most in vitro models neglect viscosity, despite evidence that viscosity is a crucial factor in the metastasis with higher blood viscosity leading to a faster rate of metastasis. By using microfluidic techniques, image processing, and computer modeling, quantitative measurements of the metastatic potential of cell lines in vitro will enable a better understanding of exactly what factors are impacting metastasis, and to what degree.
Periclimenes alcocki
Creators: name: Bruce, A. J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Palaemonidae
Periclimenes
Periclimenes alcocki

description: Periclimenes alcocki species group
Diagnosis: Periclimenes species with well developed rostrum with dorsal and ventral teeth, without supraorbital spines, inferior orbital angle without ventral flange, first pereiopods with simple fingers with entire cutting edges, second pereiopods with chelae well developed, generally moderately unequal, dissimilar, merus without distoventral tooth, ambulatory pereiopods with biunguiculate dactyls, propods spinulate (except P. albatrossae Chace & Bruce, 1993), telson with three or more pairs of dorsal spines.
description: Published as part of Bruce, A. J., 2006, Periclimenes manihine sp. nov., a new pontoniine shrimp of the P. alcocki species group (Crustacea: Decapoda: Palaemonidae), pp. 45-54 in Zootaxa 1309 on page 46, DOI: 10.5281/zenodo.173830
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice
Creators: name: Artunc, Ferruh
name: Bohnert, Bernhard N.
name: Schneider, Jonas C.
name: Staudner, Tobias
name: Sure, Florian
name: Ilyaskin, Alexandr V.
name: Wörn, Matthias
name: Essigke, Daniel
name: Janessa, Andrea
name: Nielsen, Nis V.
name: Birkenfeld, Andreas L.
name: Etscheid, Michael
name: Haerteis, Silke
name: Korbmacher, Christoph
name: Kanse, Sandip M.
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: GAMMA-SUBUNIT; CLEAVAGE; RECEPTORS; PEPTIDE; PLASMIN; MOUSE; Factor VII activating protease; FSAP-HABP2; Serine protease; Epithelial sodium channel (ENaC); Nephrotic syndrome
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: Proteolytic activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases is thought to contribute to renal sodium retention in nephrotic syndrome. However, the identity of the responsible proteases remains elusive. This study evaluated factor VII activating protease (FSAP) as a candidate in this context. We analyzed FSAP in the urine of patients with nephrotic syndrome and nephrotic mice and investigated its ability to activate human ENaC expressed in Xenopus laevis oocytes. Moreover, we studied sodium retention in FSAP-deficient mice (Habp2(-/-)) with experimental nephrotic syndrome induced by doxorubicin. In urine samples from nephrotic humans, high concentrations of FSAP were detected both as zymogen and in its active state. Recombinant serine protease domain of FSAP stimulated ENaC-mediated whole-cell currents in a time- and concentration-dependent manner. Mutating the putative prostasin cleavage site in gamma-ENaC (gamma RKRK178AAAA) prevented channel stimulation by the serine protease domain of FSAP. In a mouse model for nephrotic syndrome, active FSAP was present in nephrotic urine of Habp2(+/+) but not of Habp2(-/-) mice. However, Habp2(-/-) mice were not protected from sodium retention compared to nephrotic Habp2(+/+) mice. Western blot analysis revealed that in nephrotic Habp2(-/-) mice, proteolytic cleavage of alpha- and gamma-ENaC was similar to that in nephrotic Habp2(+/+) animals. In conclusion, active FSAP is excreted in the urine of nephrotic patients and mice and activates ENaC in vitro involving the putative prostasin cleavage site of gamma-ENaC. However, endogenous FSAP is not essential for sodium retention in nephrotic mice.
Investigating Differences in Reaction Time and Preparatory Activation as a Result of Varying Accuracy Requirements
Creators: name: Leguerrier, Alexandra R.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2018
Subjects: Movement
Neural activation

description: The preparation and initiation of movement has previously been described using a neural accumulation model; this model involves an increase of neural activation in the motor cortex (M1) from baseline to a subthreshold level following a warning signal, which is maintained until presentation of an imperative stimulus (IS). Activity then increases until reaching movement initiation threshold. This model predicts that variability in activation during preparation may influence reaction time (RT) and its variability. The purpose of this thesis project was to determine whether differences in RT/variability of RT during the completion of tasks with varying levels of complexity may be attributable to differences in neural excitability in M1. To test this prediction, transcranial magnetic stimulation (TMS) delivered concurrently with an IS was used to determine neural excitability for movements with different accuracy demands. It was hypothesized that higher accuracy demands would result in lowered amplitude and/or greater variability of neural activation, and consequently slower/more variable RT. Fifteen healthy participants completed a simple RT task involving a targeted wrist extension movement under three different accuracy conditions (easy, moderate, difficult). TMS was delivered concurrently with the IS on 50% of trials during each condition. While pilot testing showed RT differences between accuracy conditions (Appendix A), the data presented here failed to detect significant differences in RT latency (F(2, 28) = .074, p = .929) or variability (F(1.432, 20.053) = .633, p = .538) between conditions . Similarly, no difference in MEP amplitude was observed between difficulty conditions (F(2, 28) = 2.439, p = .106). However, a subset of participants (n = 7) did show significant RT increases between easy and hard conditions (t(6) = 2.531, p = .045), but this subset still failed to show differences in MEP amplitude (t(6) = 1.157, p = .291) or variability (t(6) = 1.545, p = .173), suggesting that preparatory levels at the IS may be similar for movements involving both high and low accuracy demands.
Und Was Ist Mit Uns? – Ein Vergleich Der Situation Von Kindern Bei Einer Legalen Oder Illegalen Substanzabhängigkeit Der Eltern
Creators: name: Bachmann, Tamara
name: Seeholzer, Sabrina
name: Wildi, Anne-Joséphine
Publisher: name: Zenodo
Year: 2017
Subjects: subject: gnd:4055676-1
subject: gnd:4014516-5
subject: gnd:4000145-3

description: Die vorliegende Literaturarbeit mit dem Titel „Und was ist mit uns? - Ein Vergleich der Situation von Kindern bei einer legalen oder illegalen Substanzabhängigkeit der Eltern“ befasst sich mit der Frage, welche Auswirkungen eine legale oder illegale Substanzabhängigkeit der Eltern auf die kindliche Entwicklung hat.

In einer Vielzahl der Literatur und in den jeweiligen Interventionen in Bezug auf die Suchtthematik wird der Fokus stark auf die substanzabhängige Person gelegt. Die Kinder der Betroffenen geraten dabei in den Hintergrund. Die Autorinnen Tamara Bachmann, Sabrina Seeholzer und Anne-Joséphine Wildi stellen daher in dieser Arbeit bewusst die Kinder aus suchtbelasteten Familien in den Mittelpunkt.

Die Themen Suchtmittelabhängigkeit und kindliche Entwicklung werden aufgrund theoretischer Grundlagen erläutert. Weiter wird das Leben in einer Suchtfamilie thematisiert und aufgezeigt, welche Auswirkungen dies konkret auf die kindliche Entwicklung hat.

Die aus der Theorie gewonnenen Erkenntnisse werden anhand eines Vergleiches, inwiefern sich die Auswirkungen auf die Kinder unterscheiden, wenn diese in einer Familie mit einer legalen oder einer illegalen Suchtthematik aufwachsen, verarbeitet.

Die Arbeit zeigt unter anderem auf, welche Aufgaben die Profession der Sozialen Arbeit, in Zusammenhang mit den Kindern aus suchtbelasteten Familien, innehat.

Anhand von Fallbeispielen werden die wissenschaftlichen Erkenntnisse für die Leserschaft realistisch veranschaulicht.
description: + Code Diss LU: hslusa basa be 2017 + Fussnote: Bachelorarbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialarbeit + NL-Code: NLLUHSA201710
Würdevoll Alt Werden: Wie Professionelle Der Sozialpädagogik Menschen Mit Einer Geistigen Behinderung Im Heimkontext Würdevoll Im Alterungsprozess Begleiten Können
Creators: name: Doppmann, Raphael
name: Schmid, Josch
Publisher: name: Zenodo
Year: 2017
Subjects: subject: gnd:4055864-2
subject: gnd:4001446-0
subject: gnd:4019852-2

description: Menschen mit einer geistigen Behinderung werden im Zuge des demografischen Wandels und dank des medizinischen Fortschritts in den modernen Gesundheitssystemen immer älter. Somit erreichen auch immer mehr Menschen mit geistiger Behinderung das Rentenalter, was Institutionen im Heimkontext vor neue Herausforderungen stellt.

Die Autoren, Raphael Doppmann und Josch Schmid, gehen in vorliegender Arbeit der Frage nach, wie Professionelle der Sozialpädagogik Menschen mit einer geistigen Behinderung im Heimkontext würdevoll im Alterungsprozess begleiten können. Es soll aufgezeigt werden, wie der Alterungsprozess von Personen mit geistiger Behinderung verstanden werden kann. Dabei liegt der Fokus auf dem Übergang von der Erwerbstätigkeit in den Ruhestand.

Des Weiteren verfolgt die Arbeit das Ziel, den für die Soziale Arbeit zentralen Begriff der Würde herzuleiten und mit dem Alterungsprozess zu verknüpfen. Schliesslich sollen daraus für die Sozialpädagogik relevante Schlüsse gezogen werden, um Möglichkeiten für eine würdevolle Begleitung alter Menschen mit geistiger Behinderung durch Professionelle im Heimkontext aufzuzeigen.

Die Arbeit soll Professionellen der Sozialpädagogik den Begriff der Würde näher bringen und ihnen eine Orientierung bieten, damit die Würde ihrer Klientel auch im Übergang in den Ruhestand gewahrt wird. In der Gesellschaft besteht zwar mittlerweile auch ein positives Bild des Alters. In Zusammenhang mit Behinderung überwiegt jedoch noch immer das negative Altersbild. In diesem Sinne soll die Arbeit ein Bewusstsein für positive Assoziationen von Alter und Behinderung schaffen.
description: + Code Diss LU: hslusa basp 2017 + Fussnote: Bachelorarbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialpädagogik, 2017 + NL-Code: NLLUHSA201710
Japanolaccophilus Sato 1972
Creators: name: Balke, Michael
name: Hendrich, Lars
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dytiscidae
Japanolaccophilus

description: Genus Japanolaccophilus Satô, 1972
Type species: Neptosternus niponensis Kamiya, 1939: 32.
Diagnosis. Moderately large species of Laccophilinae (total length 3.0– 3.2 mm), with the suture between elytron and epipleuron visible dorsally (Figs 3A, D); hind angles of pronotum rounded (Fig. 1); base of pronotum straight or almost so; prosternal process deltoid, not extending beyond mesocoxae and with single posterior tip in middle, not trifid (e.g. with three needle-like tips, like Neptune's fork) (Figs 4, 3C, F).
description: Published as part of Balke, Michael & Hendrich, Lars, 2019, † Japanolaccophilus beatificus sp. n. from Baltic amber and a key to the Laccophilinae genera of the World (Coleoptera: Laccophilinae), pp. 176-182 in Zootaxa 4567 (1) on pages 176-177, DOI: 10.11646/zootaxa.4567.1.10, http://zenodo.org/record/2592976
घ ोंघा नियोंत्रण के निए याोंनत्रक, रासायनिक एवों जैनवक नवनिया
Creators: name: डॉ. प्रचण्ड प्रताप नसोंह1, डॉ. प्रेम कु मार2, डॉ. नजतेन्द्र नसोंह3, डॉ. राहुि कु मार दाोंगी4
Publisher: name: The Science world a Monthly e magazine
Year: 2024

description: मोलस्क (घोोंघा) सभी समुद्री, मीठे पानी और स्थलीय आवासोों में अच्छी तरह से ववतररत हैं। घोोंघे मीठे पानी के जीवोों का एक महत्वपूर्ण तत्व हैं, एवों वे प्राथवमक उत्पादक और वितीयक उत्पादकोों के बहुत महत्वपूर्ण उपभोक्ता हैं। अकशेरुकी और कशेरुकी दोनोों अपने आहार में घोोंघे को शावमल करते है। मीठे पानी के घोोंघे कृ वम के वलए मध्यवती मेजबान के रूप में महत्वपूर्ण हैं जो मनुष्ोों या जानवरोों में वशस्टोसोवमयावसस और वववभन्न खाद्य-जवनत कृ वम जैसी बीमाररयोों का कारर् बनते हैं और स्थलीय खेती (मवेशी , भेड़, बकरी पालन) और जलीय कृ वि (मछवलयोों पालन ) दोनोों में पशु उत्पादन को धीमा कर देते हैं। अन्य प्रजावतयााँ, ववशेि रूप से सेब घोोंघे गोंभीर कृ वि कीट हैं जो नए लगाए गए चावल के खेतोों को महत्वपूर्ण नुकसान पहुोंचाते हैं। इसके अलावा, एवशया में घोोंघे की कई प्रजावतयोों को मनुष्ोों के भोजन के रूप में उपयोग वकया जाता है।
Polyschides Pilsbry & Sharp 1898
Creators: name: Caetano, Carlos Henrique Soares
name: Absalão, Ricardo Silva
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Scaphopoda
Gadilida
Gadilidae
Polyschides

description: Genus Polyschides Pilsbry & Sharp, 1898
Type species: Cadulus tetraschistus Watson, 1879, by original designation.
description: Published as part of Caetano, Carlos Henrique Soares & Absalão, Ricardo Silva, 2005, A new species of the genus Polyschides Pilsbry & Sharp, 1898 (Mollusca, Scaphopoda, Gadilidae) from Brazilian waters, pp. 1-10 in Zootaxa 871 on page 3, DOI: 10.5281/zenodo.170884
Potenziale Der Offenen Kinder- Und Jugendarbeit: Ideen Einer Weiterentwicklung Der Offenen Kinder- Und Jugendarbeit In Ländlichen Gemeinden
Creators: name: Luca, Baldelli
name: Jonas, Werder
Publisher: name: Zenodo
Year: 2017
Subjects: subject: gnd:4299677-6
subject: gnd:4028863-8

description: Ländliche Gemeinden sehen sich mit gesellschaftlichen Veränderungen konfrontiert. Traditionelle Lebensformen weichen individuellen Lebensentwürfen. Die soziale Bindung unter den Einwohnerinnen und Einwohnern geht mehr und mehr verloren. Besonders ländliche Gemeinden sind auf Beteiligung und Engagement der Bevölkerung angewiesen. Den Behörden stellen sich dadurch verschiedene Herausforderungen im gesellschaftlichen Zusammenleben. Ländliche Gemeinden mit einem bestehenden Angebot Offener Kinder- und Jugendarbeit verfügen über Fachpersonen in der Gestaltung gemeinschaftlicher Prozesse. Die Einrichtungen der Offenen Kinder- und Jugendarbeit selbst kämpfen jedoch mit Schwierigkeiten. Fehlende finanzielle Mittel und kleine Arbeitspensen verhindern die professionelle Erfüllung des Kernauftrags im Sinne der Kinder und Jugendlichen. Die Potenziale der Soziokulturellen Animation, die in der Offenen Kinder- und Jugendarbeit vorhanden sind, scheinen ein adäquater Ansatzpunkt zu sein, um sich als Institution der Offenen Kinder- und Jugendarbeit weiterzuentwickeln und sich der Herausforderungen der ländlichen Gemeinden in Bezug auf das gesellschaftliche Zusammenleben anzunehmen. Doch durch die Übernahme von neuen Aufträgen besteht für die Offene Kinder- und Jugendarbeit die Gefahr, den Kernauftrag zu vernachlässigen. Ihre Rolle in solchen Entwicklungsprozessen wird aufgezeigt, analysiert und bewertet. Daraus werden abschliessend Schlussfolgerungen für die Praxis gezogen. Diese Handlungsansätze verfolgen die Steigerung der Qualität von bestehenden Einrichtungen der Offenen Kinder- und Jugendarbeit in der Erfüllung ihres Kernauftrags.
description: + hslusa bask 2017 + Fussnote: Bachelorarbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Soziokultur, 2017 + NL-Code: NLLUHSA201710
Suchterkrankung Und Trauma – Die Herausforderung Für Fachkräfte Der Sozialpädagogik Bei Verstärktem Hervortreten Von Traumata Während Des Abbaus Von Substitutionen: Konkrete Traumapädagogische Handlungsansätze Für Die Stationäre Suchttherapie
Creators: name: Kellerhals, Corinne
name: Barraud, Florence
Publisher: name: Zenodo
Year: 2017
Subjects: subject: gnd:4055864-2
subject: gnd:4058361-2
subject: gnd:4060748-3

description: Laut Statistiken leiden ca. 80% der Suchterkrankten an einer Doppeldiagnose. Häufig ist die Kombination von Suchterkrankung und Trauma anzutreffen, weshalb der schwierige Umgang als Fachkraft mit den Betroffenen untersucht wird. Im Jahr 2016 waren 39% der Suchterkrankten zum Zeitpunkt des Eintritts in eine stationäre Suchttherapie substituiert. Besonders der Abbau der Substitution ist heikel, da die verdeckten Traumata vermehrt in den Vordergrund treten. Das veränderte Verhalten der Betroffenen ist für Fachkräfte der Sozialpädagogik schwierig zu verstehen und zu handhaben, denn die Thematik wird immer noch als therapeutisches Thema angesehen. Die Möglichkeiten der Sozialpädagogik werden zu wenig erkannt und dadurch Chancen vergeben.

Zuerst wird das fehlende Fachwissen der Fachkräfte durch Hintergrundwissen zu Suchterkrankung, Trauma und Substitutionsabbau abgedeckt. Anschliessend werden die konkreten Zusammenhänge zwischen diesen drei Themen herausgearbeitet. Basierend auf den Ergebnissen folgt die Thematisierung der Aufgaben und Herausforderungen in der stationären Suchttherapie. Fehlender Resilienz und der Gruppendynamik der Klientel sowie Konflikten innerhalb des Arbeitsteams wird mit Kernaspekten der Traumapädagogik, Resilienz- und Selbstwirksamkeitsförderung, Raumgestaltung, Trauma-Gruppenpädagogik und Fachkräften als Schlüsselfunktion begegnet.

Ziel der Autorinnen, Corinne Kellerhals und Florence Barraud, ist es, Fachkräften der Sozialpädagogik in der stationären Suchttherapie sowie deren Vorgesetzten die Notwendigkeit von fundiertem Fachwissen, Selbstreflexion, klarer Organisationsstruktur und einem unterstützenden Arbeitsteam im Umgang mit dieser Klientel aufzuzeigen.
description: + Code Diss LU: hslusa basp be 2017 + Fussnote: Bachelorarbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialpädagogik, 2017 + NL-Code: NLLUHSA201710
EFFICIENCY OF COTTON GROWING WITH BOMS PHYSIOLOGICAL ACTIVE SUBSTANCE WITHOUT THE APPLICATION OF MINERAL FERTILIZERS IN COTTON GROWING
Creators: name: Raximova, Dilobar
name: Ergasheva, Nargiza
name: Xolmirzayev, Azizbek
name: Saydullayeva, Mehriniso
name: Bekchanov, Azamatjon
Publisher: name: Zenodo
Year: 2024

description: Cotton growing is the main sector in Uzbekistan's agriculture, and the republic has accumulated a lot of scientific and practical experience in agro-technologies of cotton cultivation. The unique soil and climate conditions of the republic create natural difficulties in cotton cultivation. Early spring rains and early onset of cold weather in autumn, i.e. snow or rain in early October, make it difficult for the cotton crop to ripen and be harvested. For this reason, the selection of early cotton varieties and the development of intensive agrotechnical measures are of great importance in the cotton industry of Uzbekistan. Although almost all of the cotton varieties planted in the republic today are early varieties, due to the strong influence of the weather, the cotton harvest continues until November, and the production of high-quality cotton crops has become a problem. A lot of scientific research is being conducted in this regard.
OS DIREITOS FUNDAMENTAIS AO MEIO AMBIENTE  ECOLOGICAMENTE EQUILIBRADO E À SAÚDE E OS  CONFLITOS DE PODER:  UMA ANÁLISE DO PROBLEMA DA POLUIÇÃO DO AR POR  PARTICULADO DE MINÉRIO EM VITÓRIA-ES
Creators: name: Ivy de Souza Abreu
name: Elda Coelho de Azevedo Bussinguer
Publisher: name: Zenodo
Year: 2015

description: SUMÁRIO: 1 Introdução. 2 Os direitos fundamentais ao meio ambiente ecologicamente equilibrado e à saúde. 3 A biopolítica e o biopoder em michel foucault. 4 O problema ambiental do particulado de minério em vitória-es à luz dos conflitos biopolíticos. 5 Considerações finais. Referências.
Elucidation of the anti-fibrotic diseases mechanism of chelerythrine by integrative approach of network pharmacology and experimental verification
Creators: name: Han, Wei
name: Qian, Gui-yun
name: Wang, Qin-rong
name: Liu, Jie
name: Zhang, Yong-ping
name: Xu, Jian
name: Li, Tingting
name: Li, Zhe
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: In the present study, we conducted an integrative approach of network pharmacology and experimental validation study to elucidate the underlying mechanisms of Chelerythrine (CLT), in treating fibrotic diseases (FD), which are disorders characterised by excessive accumulation of extracellular matrix. 27 common targets of CLT against FD were analysed, and these common targets were used to construct the PPI network. The results of GO and KEGG enrichment analyses suggested that CLT exerted pharmacological effects on FD by regulating mTOR signalling pathway, AKT-PI3K pathway and apoptosis signalling pathway. Finally, molecular docking confirmed a strong binding affinity between CLT and the core target proteins. CLT has inhibitory effects on the proliferation and migration of L929 cells, CLT could promote cell apoptosis. CLT decreased levels of the Bcl-2, p-AKT/AKT, p-mTOR/mTOR and p-PI3K/PI3K, meanwhile increased levels of the Bax. Taken together, these results indicate that CLT may be a potential drug for anti-fibrotic diseases therapy.
Bio-active metabolites from Chinese Medicinal Herbs for treatment of skin diseases
Creators: name: Wu, Xiao Xiao
name: Law, Siu Kan
name: Ma, Hui
name: Jiang, Zhou
name: Li, Yi Fan
name: Au, Dawn Ching Tung
name: Wong, Chun Kwok
name: Luo, Di Xian
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Skin diseases have become serious issues to human health and affect one-third of the world’s population according to the World Health Organisation (WHO). These consist of internal (endogenous) and external (exogenous) factors referring to genetics, hormones, and the body’s immune system, as well as environmental situations, UV radiation, or environmental pollution respectively. Generally, Western Medicines (WMs) are usually treated with topical creams or strong medications for skin diseases that help superficially, and often do not treat the root cause. The relief may be instant and strong, sometimes these medicines have adverse reactions that are too strong to be able and sustained over a long period, especially steroid drug type. Chinese Medicinal Herbs (CMHs) are natural resources and relatively mild in the treatment of both manifestation and the root cause of disease. Nowadays, CMHs are attractive to many scientists, especially in studying their formulations for the treatment of skin diseases. Methods: The methodology of this review was searched in nine electronic databases including WanFang Data, PubMed, Science Direct, Scopus, Web of Science, Springer Link, SciFinder, and China National Knowledge Infrastructure (CNKI), without regard to language constraints. All eligible studies are analysed and summarised. Results: Based on the literature findings, some extracts or active metabolites divided from CMHs, including Curcumin, Resveratrol, Liquorice, Dandelions, Cortex Moutan, and Calendula officinalis L., are effective for the treatment and prevention of skin diseases because of a wide range of pharmacological activities, e.g. anti-bacterial, anti-microbial, anti-virus, and anti-inflammation to enhance the body’s immune system. It is also responsible for skin whitening to prevent pigmentation and premature ageing through several mechanisms, such as regulation or inhibition of nuclear factor kappa B (IκB/NF-κB) signalling pathways. Conclusion: This is possible to develop CMHs, such as Curcumin, Resveratrol, Liquorice, Dandelions, Cortex Moutan and Calendula officinalis L. The ratio of multiple CMH formulations and safety assessments on human skin diseases required studying to achieve better pharmacological activities. Nano formulations are the future investigation for CMHs to combat skin diseases.
A stabilized total pressure-formulation of the Biot's poroelasticity equations in frequency domain: Numerical analysis and applications
Creators: name: Cárcamo, Cristian
name: Caiazzo, Alfonso
name: Galarce, Felipe
name: Mura, Joaquín
Publisher: name: Weierstrass Institute
Year: 2024
Subjects: subject: Biot
subject: poroelasticity
subject: magnetic resonance elastography
subject: stabilized finite element
subject: 65N30
subject: 76S05
subject: 74F10

description: This work focuses on the numerical solution of the dynamics of a poroelastic material in the frequency domain. We provide a detailed stability analysis based on the application of the Fredholm alternative in the continuous case, considering a total pressure formulation of the Biot's equations. In the discrete setting, we propose a stabilized equal order finite element method complemented by an additional pressure stabilization to enhance the robustness of the numerical scheme with respect to the fluid permeability. Utilizing the Fredholm alternative, we extend the well-posedness results to the discrete setting, obtaining theoretical optimal convergence for the case of linear finite elements. We present different numerical experiments to validate the proposed method. First, we consider model problems with known analytic solutions in two and three dimensions. As next, we show that the method is robust for a wide range of permeabilities, including the case of discontinuous coefficients. Lastly, we show the application for the simulation of brain elastography on a realistic brain geometry obtained from medical imaging.