cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Retrospectives
Creators: name: Author, Unknown
Publisher: name: University of Lincoln
Year: 2024
Subjects: K250 - Conservation of buildings
W740 - Surface decoration

description: Crick Smith researched and produced a palette of colours that defined the domestic paintsused in England during the 1960s, 70s & 80s for English Heritage and The Little Greene PaintCompany. The authentic colours with identified provenance defined fashionable tastes of thelate C20th and were marketable at the current time and ongoing. If suitable, the originalÃ¢â‚¬ËœperiodÃ¢â‚¬â„¢ name was retained.The project incorporated reviewing records of previous research on properties of the periodwithin the National Archive for Historic Decoration. The British Newspaper Archives allowedaccess to period journals and magazines, e.g. Ã¢â‚¬ËœIdeal HomeÃ¢â‚¬â„¢ and Ã¢â‚¬ËœHomes & GardensÃ¢â‚¬â„¢. Paintmanufacturers were contacted for information of paint ranges of that time. The preferredpalettes of architects and designers of the period was investigated. Origins of colours,particularly those Ã¢â‚¬ËœnewÃ¢â‚¬â„¢ to England was researched including social influences, aspiration ofsociety and effects of immigrant communities on interior styles and colours used.Ranges of colour based upon uses, popularity and context were produced. Palettes werepresented to focus groups of suitable demographics, to assess responses, reminiscences,associations generated when colours were viewed individually and in groups of each era.Focus groups included those with memories of these colours and groups for whom therewere no previous period associations.The research method, information sources, results of analysis and focus group responseswas recorded. A calibrated spectrophotometer produced a numerical reference for eachcolour.The clients produced a successful marketable range of paints, which was launched atDecorex International 2011.As Crick Smith reports are written for a range of clients, information is deliberately presentedin a style that is easily accessible, technical terms are fully explained enabling understandingby non-specialist readers, as it is understood that not all members of the client team may beexperienced in understanding this type of investigation.
Sodium bisulfite pyrosequencing revealed that developmental exposure to environmental contaminant mixtures does not affect DNA methylation of DNA repeats in Sprague-Dawley rats
Creators: name: Desaulniers, Daniel
name: Cummings-Lorbetskie, Cathy
name: Nanqin Li
name: Xiao, Gong-Hua
name: Marro, Leonora
name: Khan, Nasrin
name: Leingartner, Karen
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Hypomethylation of DNA repeats has been linked to diseases and cancer predisposition. Human studies suggest that higher blood concentrations of environmental contaminants (EC) correlate with levels of hypomethylation of DNA repeats in blood. The objective of this study was to examine the effect of in utero and/or lactational exposure to EC on the methylation of DNA repeats (LINE-1 and identifier element) in Sprague-Dawley rat pups at birth, at postnatal day (PND) 21, and in adulthood (PND78–86). From gestation day 0 to PND20, dams were exposed to a mixture “M” of polychlorinated biphenyls (PCB), pesticides, and methylmercury (MeHg), at 0.5 or 1 mg/kg/d (0.5M and M). At birth, some control (C) and M litters were cross-fostered to create the following in utero/postnatal exposure groups: C/C, M/C, C/M, M/M. Additional dams received 1.8 ng/kg/d of a mixture of aryl-hydrocarbon receptor (AhR) agonists (non-ortho-PCB, PC-dibenzodioxins, and PC-dibenzofurans) without or with 0.5M (0.5MAhR). Measurements of EC residue levels confirmed differences in their accumulation across treatments, age, and tissues. Although induction of hepatic detoxification enzyme activities (cytochrome P-450) demonstrated biological effects of treatments, the assessment of methylation in DNA repeats by sodium bisulfite pyrosequencing of liver, spleen, and thymus samples revealed no marked treatment-related effects but significant tissue- and age-related methylation differences. Further studies are required to determine whether absence of significant observable treatment effects on methylation of DNA repeats in the rat relate to tissue, strain, or species differences.
The Pedagogical Potential of Block Teaching in Higher Education Blog
Creators: name: Shabnam, Nourin
Publisher: name: National Teaching Repository
Year: 2025
Subjects: classificationCode: 390102
subject: Curriculum and pedagogy theory and development

description: This blog post expands on The Pedagogical Potential of Block Teaching in Higher Education poster, which explores the pedagogical benefits and challenges of block teaching in higher education, highlighting its potential to enhance engagement, inclusivity, and deep learning through focused, time-compressed delivery.
Historical Diets of Forage Fish and Juvenile Pacific Salmon in the Strait of Georgia, 1966–1968
Creators: name: Osgood, Geoffrey J.
name: Kennedy, Laura A.
name: Holden, Jessica J.
name: Hertz, Eric
name: McKinnell, Skip
name: Juanes, Francis
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The Strait of Georgia, British Columbia, provides important feeding and rearing habitat for forage fish, such as Pacific Herring Clupea pallasii and Eulachon Thaleichthys pacificus as well as all species of North American Pacific salmon Oncorhynchus spp. during their juvenile out-migration. In recent decades, this region has undergone large-scale physical and biological changes. Pacific Herring and Pacific salmon populations have experienced dramatic population fluctuations, while Eulachon have failed to recover from precipitous declines in the 1990s. Archival records of stomach content data from the 1960s, collected primarily from juvenile Pacific salmon, Pacific Herring, and Eulachon, allowed us to investigate diet variability in these species 60 years ago. Consistent with contemporary reports, we found that all species except Eulachon had generalist diets. In contrast to recent studies finding that Pacific Herring are the most important fish prey, Eulachon were the most frequently consumed fish, occurring in 28% of all piscivorous fish stomachs. This suggests that Pacific Herring are an important component of some Pacific salmon diets now, but only because lipid-rich Eulachon are no longer available. Chinook Salmon O. tshawytscha and Coho Salmon O. kisutch had the most similar diets, in part because of their greater piscivory. Species, length, and month and year of capture showed some explanatory power in differentiating the diets of the fish, although they explained less than 10% of total diet variation. Historical data, such as those presented here, offer a unique opportunity to investigate temporal differences in foraging ecology, informing management on how changes in the Strait of Georgia ecosystem may impact the trophic interactions between species. Received September 30, 2015; accepted July 5, 2016
Associations between omega-3 fatty acids, selenium content, and mercury levels in wild-harvested fish from the Dehcho Region, Northwest Territories, Canada
Creators: name: Reyes, Ellen S.
name: Henao, Juan J. Aristizabal
name: Kornobis, Katherine M.
name: Hanning, Rhona M.
name: Majowicz, Shannon E.
name: Liber, Karsten
name: Stark, Ken D.
name: Low, George
name: Swanson, Heidi K.
name: Laird, Brian D.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: To better understand the risks and benefits of eating wild-harvested fish from the Northwest Territories, Canada, levels of total mercury (HgT) and selenium (Se) and composition of omega-3 fatty acid (n-3 FA) were measured in muscle tissue of fish harvested from lakes in the Dehcho Region, Northwest Territories, Canada. Average HgT levels ranged from 0.057 mg/kg (cisco) to 0.551 mg/kg (northern pike), while average n-3 FA concentrations ranged from 101 mg/100 g (burbot) to 1,689 mg/100 g (lake trout). In contrast to HgT and n-3 FA, mean Se concentrations were relatively similar among species. Consequently, species such as lake whitefish, cisco, and longnose sucker displayed the highest nutrient levels relative to HgT content. Levels of HgT tended to increase with fish size, while Se and n-3 FA levels were typically not associated with fork length or fish weight. Interestingly, HgT concentration was occasionally inversely related to tissue nutrient content. Significant negative correlations were observed between Hg and n-3 FA for lake trout, northern pike, and walleye. There were also significant negative correlations between Hg and Se noted for lake whitefish, cisco, and northern pike. Samples with the highest nutritional content displayed, on occasion, lower levels of HgT. This study provides valuable information for the design of probabilistic models capable of refining public health messaging related to minimizing Hg risks and maximizing nutrient levels in wild-harvested fish in the Canadian subarctic.
Cu-Sn binary metal particle generation by spray pyrolysis
Creators: name: Yujia Liang
name: Felix, Ryan
name: Glicksman, Howard
name: Ehrman, Sheryl
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: 60506 Virology

description: Cu-Sn binary particles were generated via spray pyrolysis from metal salt precursors with ethylene glycol as the co-solvent and reducing agent. The morphology, crystallinity, and elemental distribution of particles were tunable by changing the reaction temperature, residence time, and quench gas flow rate. Hollow porous particles were fabricated with a higher Sn concentration on the particle surface when the furnace set point was 500°C, while solid particles with a lower surface Sn concentration were generated when the furnace set point was 1000°C. Particles with spherical morphologies were obtained at long residence time conditions (4.5 s). Cu-Sn binary particles with irregular structures (e.g., pores on the particle surface, fragmented spherical particles, and lamellar fragments) were formed at short residence time conditions (0.92 s). A possible spray pyrolysis mechanism was proposed that incorporates chemical reaction steps and structural progression. By this mechanism, the metal salts are believed to sequentially undergo hydrolysis to metal hydroxides, decomposition to metal oxides, reduction to metals, and finally diffusion of Sn into the Cu matrix to generate the Cu-Sn solid solution. Copyright © 2017 American Association for Aerosol Research
İslamcı Feminizmin Toplumsal Pratiği
Creators: name: Çetin, Esad
Publisher: name: figshare
Year: 2020
Subjects: subject: 160810 Urban Sociology and Community Studies
subject: FOS: Sociology

description: This paper, mainly wishes to point out some concepts and facts like "feminism" and “islamism” and its consequence as a social fact which is being revealed in societies. But before it, we are supposed to figure out what the essence of “fenimism” is. To not make an anachronic interpretation to social analysis, also this paper wishes to reveal the historical context of these concepts. So to say, we are rethinking the “feminism” and its “results” in practical way. The idea called “practical way”, which feminism is supposed to use merely it, is the fundement of this study. Because the feminism is practical movement in societies rather than theoretical or philosophical investigation or etc. As a consequence the practically valid dynamics in this country and society are interested in Islamic studies so called “Islamism”. The relation between Islamism and Feminism were been shown and also it were been shown that the feminism is a modern fact because of this relation. We endeavour to show that not purely “feminism” but “the fact that feminism is in this society” is modern. Feminism influenced publics with some reasonings all around the world. But those reasonings are not very philophical investigation or not the ideas which have theoretical ground.
Suppression of starch accumulation in ‘sugar leaves’ of rice affects plant productivity under field conditions
Creators: name: Okamura, Masaki
name: Tatsuro Hirose
name: Hashida, Yoichi
name: Ohsugi, Ryu
name: Aoki, Naohiro
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: While many plants accumulate the majority of their photoassmilates as starch during the daytime, some plants accumulate sucrose. Although the existence of these high-sucrose leaves, called ‘sugar leaves’, has long been known, the physiological characteristics of sugar leaves compared to ‘starch leaves’ remain unclear. In this study, the physiological roles of starch accumulation in rice, which has typical sugar leaves, were investigated using a mutant with suppressed leaf-starch biosynthesis. When grown under controlled conditions with light intensity of 400 μmol m−2 s−1, the initial growth of the mutant was similar to that of the wild-type plant, even with a 6-h-light/18-h-dark photoperiod in which carbon resources for growth are required during the night. This finding indicates that rice does not rely on leaf starch as a carbon resource during the night. By contrast, under field conditions, the grain yields of the mutant were significantly lower than those of the wild type only when the plants were exposed to full sunlight during the ripening period. These results may indicate that starch accumulation in sugar leaves plays an important role in maintaining a high source capacity under sufficient light conditions rather than as a carbon resource for the plant’s growth at night.
829053755_33-Esad Çetin.pdf
Creators: name: Çetin, Esad
Publisher: name: figshare
Year: 2020
Subjects: subject: 160810 Urban Sociology and Community Studies
subject: FOS: Sociology

description: This paper, mainly wishes to point out some concepts and facts like "feminism" and “islamism” and its consequence as a social fact which is being revealed in societies. But before it, we are supposed to figure out what the essence of “fenimism” is. To not make an anachronic interpretation to social analysis, also this paper wishes to reveal the historical context of these concepts. So to say, we are rethinking the “feminism” and its “results” in practical way. The idea called “practical way”, which feminism is supposed to use merely it, is the fundement of this study. Because the feminism is practical movement in societies rather than theoretical or philosophical investigation or etc. As a consequence the practically valid dynamics in this country and society are interested in Islamic studies so called “Islamism”. The relation between Islamism and Feminism were been shown and also it were been shown that the feminism is a modern fact because of this relation. We endeavour to show that not purely “feminism” but “the fact that feminism is in this society” is modern. Feminism influenced publics with some reasonings all around the world. But those reasonings are not very philophical investigation or not the ideas which have theoretical ground.
Devonian porphyry Cu deposits in NW China: the Xiaotuergen example
Creators: name: Xinxia Geng
name: Fuquan Yang
name: Jihua Qin
name: Chaoquan Wen
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: Science Policy

description: The Nuoerte Basin in northern Altay contains numerous mineral discoveries, including the Xiaotuergen porphyry Cu, Kumasu VMS Pb–Zn, and Hongshanzui orogenic Au deposits. This deposit, newly discovered by the 4th Geological Team of XJBGMR – the Xiaotuergen porphyry Cu deposit – is mainly hosted along the contact zone between the granodiorite porphyry and the Nuoerte Formation volcanic-sedimentary rocks. Disseminated, veinlet, veinlet-disseminated, and stockwork Cu mineralization occur in the granodiorite porphyry. Wall-rock alteration styles include mainly potassic (K-feldspar and biotite), silicic, carbonate, sericite, pyrite, chlorite, and epidote alterations. In this study, we used LA-ICP-MS zircon dating for the various rock types in the Xiaotuergen Cu ore district. The tuff at the periphery of the ore district has been newly dated to be ca. 411 Ma. This, together with stratigraphic correlation, suggests that the local stratigraphy is the Lower Devonian Nuoerte Formation, rather than the Lower Carboniferous Hongshanzui Formation as previously assumed. The ore-hosting granodiorite porphyry, quartz porphyry, biotite monzogranite, and granite porphyry are dated to be ca. 405 Ma, 400 Ma, 398 Ma, and 397 Ma, respectively. This constrains the Cu mineralization to be slightly younger than 405 Ma, and indicates that they may have belonged to the same Early Devonian intrusive event. Magmatism at Xiaotuergen had recommenced in the Late Devonian, as represented by minor granite porphyry dikes (ca. 370 Ma) intruding the ore-hosting granodiorite porphyry.
Pre-hospital Anticholinergic Burden and Delirium in Critically Ill Patients
Creators: name: Khalil, Hussein Mohamad
Publisher: name: Purdue University Graduate School
Year: 2025
Subjects: classificationCode: 420204
subject: Epidemiological methods
classificationCode: 321403
subject: Clinical pharmacy and pharmacy practice

description: This work investigates the relationship between pre-hospital cumulative anticholinergic medication use and delirium outcomes in critically ill patients. Delirium is a frequent and serious complication in ICU settings and is associated with poor clinical outcomes, yet the role of chronic anticholinergic exposure remains unclear. The research includes three components: (1) a systematic review of studies examining community-based anticholinergic use and delirium outcomes, (2) a secondary analysis evaluating the association between 5-year cumulative anticholinergic burden and prevalent delirium at ICU admission, and (3) a secondary analysis exploring the relationship between pre-hospital anticholinergic burden, delirium severity, and short-term mortality. Anticholinergic burden was quantified using Total Standardized Daily Doses (TSDD), a dose- and duration-sensitive metric. The systematic review found consistent associations between high anticholinergic burden and delirium, though studies in critically ill patients assessing delirium severity and duration were limited. In the second study, higher cumulative burden was significantly associated with increased delirium prevalence, particularly among patients aged 50 and older. However, pre-hospital anticholinergic burden was not associated with delirium severity or 30- and 90-day mortality. These findings underscore anticholinergic medications as a potentially modifiable predisposing risk factor for delirium and highlight the need for better exposure measurement and deprescribing strategies in vulnerable populations.
Explications relatives à un couplet de farandole
Creators: name: Lancelot, Francine
name: MS Pelissier
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/FileId-3413
description: created: ca 1970
Réflexions sur le commandement à la mer. Communication à la onzième journée du GDR Cadres (résumé)
Creators: name: Descleves (Vice-Amiral), Emmanuel
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019
Subjects: Aptitude pour la direction
Forces armées -- Direction

description: "Tout a probablement été écrit en cette matière; le commandement a fait l’objet de nombreux essais, mais aussi de quantité de témoignages concrets d’hommes célèbres et de grands chefs de guerre maîtres dans cet art. Pour autant, les bibliothèques ne contiennent à ma connaissance aucun ouvrage dont la prétention serait de définir les règles du commandement. Sans doute pour cette simple raison qu’il n’en existe probablement pas non plus pour être père de famille ou ministre ? Mon propos est donc de rassembler quelques observations, non pas nouvelles mais choisies et présentées selon ma propre expérience, à titre de témoignage." [Premières lignes]
description: Temporal: 2000-2010
Biodegradation of low and high molecular weight hydrocarbons in petroleum refinery wastewater by a thermophilic bacterial consortium
Creators: name: Arulazhagan Pugazhendi
name: Hadeel Abbad Wazin
name: Qari, Huda
name: Basahi, Jalal Mohammad Al-Badry
name: Godon, Jean Jacques
name: Dhavamani, Jeyakumar
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: Clean-up of contaminated wastewater remains to be a major challenge in petroleum refinery. Here, we describe the capacity of a bacterial consortium enriched from crude oil drilling site in Al-Khobar, Saudi Arabia, to utilize polycyclic aromatic hydrocarbons (PAHs) as sole carbon source at 60°C. The consortium reduced low molecular weight (LMW; naphthalene, phenanthrene, fluorene and anthracene) and high molecular weight (HMW; pyrene, benzo(e)pyrene and benzo(k)fluoranthene) PAH loads of up to 1.5 g/L with removal efficiencies of 90% and 80% within 10 days. PAH biodegradation was verified by the presence of PAH metabolites and evolution of carbon dioxide (90 ± 3%). Biodegradation led to a reduction of the surface tension to 34 ± 1 mN/m thus suggesting biosurfactant production by the consortium. Phylogenetic analysis of the consortium revealed the presence of the thermophilic PAH degrader Pseudomonas aeruginosa strain CEES1 (KU664514) and Bacillus thermosaudia (KU664515) strain CEES2. The consortium was further found to treat petroleum wastewater in continuous stirred tank reactor with 96 ± 2% chemical oxygen demand removal and complete PAH degradation in 24 days.
Global impact of a climate treaty if the Human Development Index replaces GDP as a welfare proxy
Creators: name: Bergh, Jeroen C. J. M. Van Den
name: W. J. Wouter Botzen
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: This study explores the implications of shifting the narrative of climate policy evaluation from one of costs/benefits or economic growth to a message of improving social welfare. Focusing on the costs of mitigation and the associated impacts on gross domestic product (GDP) may translate into a widespread concern that a climate agreement will be very costly. This article considers the well-known Human Development Index (HDI) as an alternative criterion for judging the welfare effects of climate policy. We estimate what the maximum possible annual average increase in HDI welfare per tons of CO2 would be within the carbon budget associated with limiting warming to 2°C over the period 2015–2050. Emission pathways are determined by a policy that allows the HDI of poor countries and their emissions to increase under a business-as-usual development path, while countries with a high HDI value (>0.8) have to restrain their emissions to ensure that the global temperature rise does not exceed 2°C. For comparison, the well-known multi-regional RICE model is used to assess GDP growth under the same climate change policy goals. Policy relevance This is the first study that shifts the narrative of climate policy evaluation from one of GDP growth to a message of improving social welfare, as captured by the HDI. This could make it easier for political leaders and climate negotiators to publicly commit themselves to ambitious carbon emission reduction goals, such as limiting global warming to 2°C, as in the (non-binding) agreement made at COP 21 in Paris in 2015. We find that if impacts are framed in terms of growth in HDI per t CO2 emission per capita instead of in GDP, the HDI of poor countries and their emissions are allowed to increase under a business-as-usual development path, whereas countries with a high HDI (>0.8) must control emissions so that global temperature rise remains within 2°C. Importantly, a climate agreement is more attractive for rich countries under the HDI than the GDP frame. This is good news, as these countries have to make the major contribution to emissions reductions.
Research and investigation and reinstatement of the early decorative scheme at the Church of St. James the Less, New Mills, Derbyshire
Creators: name: Croft, Paul
Publisher: name: University of Lincoln
Year: 2024
Subjects: K250 - Conservation of buildings

description: In 2011 Crick Smith conservation conducted architectural paint research on the extant decorative scheme at the Church of St. James the Less, New Mills, Derbyshire. This research concluded that a decorative scheme of c. 1880 lay under layers of modern decoration. Crick Smith were then commissioned to reveal sections of the earlier scheme and then to reinstate the original scheme in its entirety on one wall.Initial phase of the research consisted a programme of on site sampling of accumulated paint layers from key locations. Analysis of samples was undertaken by optical microscopy using a variety of different lighting techniques to reveal the chemical make up within the build up of individual paint layers, which assists dating the paint by determining the metal oxide driers used (e.g: lead, zinc etc). The results of the samples showed where to uncover areas of the original decorative stencil scheme, which allowed colours to be quantified using a spectrophotometer ensuring authentic reinstatement. This evidence was corroborated by archival evidence in accounts dated c1880 of the buildingâ€™s decorative appearance, along with photographs of c1910. Reinstatement was necessitated by the loss of the original plaster. Based on the evidence uncovered, this led to a second phase of targeting uncovering work to reveal and record the original 1880â€™s stencil scheme to the extent where the repeat design could be extrapolated for reinstatement. Crick Smith reports are written for a range of clients, information is deliberately presented in a style that is easily accessible, technical terms are fully explained to enable understanding by a non-Â­?specialist reader, as it is understood that not all members of the client team may be experienced in understanding this type of investigation.
Molecular and morphological characterization of Moniliophthora roreri isolates from cacao in Ecuador
Creators: name: Maridueña-Zavala, María Gabriela
name: Villavicencio-Vásquez, Mirian Elizabeth
name: Cevallos-Cevallos, Juan Manuel
name: Peralta, Esther Lilia
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Moniliophthora roreri – the causal agent of frosty pod rot (FP) disease – is one of the most devastating cacao pathogens in Ecuador and worldwide. The centre of diversity of this pathogen is believed to be in areas near Ecuador or Colombia but molecular, morphological and growth studies of this pathogen in Ecuador are scarce. Monosporic cultures of M. roreri from the six cacao-producing regions of Ecuador, including Esmeraldas, El Oro, Los Rios, Guayas, Manabi and Amazon were obtained. Morphological characteristics, such as mycelial growth, colony shape, colour and texture, as well as type and size of meiospores, were recorded for each isolate. Molecular variation was assessed by direct sequencing the ITS1, 5.8 s, and ITS2 rDNA regions as well as by RFLP analyses on the same regions. Results showed little variation of morphological traits across isolates. Mycelial growth rate fitted to a Gompertz model with parameters estimates that were significantly affected by mycelial colour. Molecular analysis data showed an average polymorphism of 48.98% and Shannon’s diversity index of 0.21. Multiple discriminant analyses carried out on the RFLP patterns showed a 100% accurate grouping by both sampling province and mycelial colour.
Research and investigation and reinstatement of the early decorative scheme at the Church of St. James the Less, New Mills, Derbyshire
Creators: name: Author, Unknown
Publisher: name: University of Lincoln
Year: 2024
Subjects: K250 - Conservation of buildings

description: In 2011 Crick Smith conservation conducted architectural paint research on the extant decorative scheme at the Church of St. James the Less, New Mills, Derbyshire. This research concluded that a decorative scheme of c. 1880 lay under layers of modern decoration. Crick Smith were then commissioned to reveal sections of the earlier scheme and then to reinstate the original scheme in its entirety on one wall.Initial phase of the research consisted a programme of on site sampling of accumulated paint layers from key locations. Analysis of samples was undertaken by optical microscopy using a variety of different lighting techniques to reveal the chemical make up within the build up of individual paint layers, which assists dating the paint by determining the metal oxide driers used (e.g: lead, zinc etc). The results of the samples showed where to uncover areas of the original decorative stencil scheme, which allowed colours to be quantified using a spectrophotometer ensuring authentic reinstatement. This evidence was corroborated by archival evidence in accounts dated c1880 of the buildingÃ¢â‚¬â„¢s decorative appearance, along with photographs of c1910. Reinstatement was necessitated by the loss of the original plaster. Based on the evidence uncovered, this led to a second phase of targeting uncovering work to reveal and record the original 1880Ã¢â‚¬â„¢s stencil scheme to the extent where the repeat design could be extrapolated for reinstatement. Crick Smith reports are written for a range of clients, information is deliberately presented in a style that is easily accessible, technical terms are fully explained to enable understanding by a non-Ã‚Â­?specialist reader, as it is understood that not all members of the client team may be experienced in understanding this type of investigation.
Research and conservation of four spirit fresco mural at the Church of St. James the Less, New Mills, Derbyshire
Creators: name: Maloney, Jade
Publisher: name: University of Lincoln
Year: 2024
Subjects: K250 - Conservation of buildings

description: In 2011 Crick Smith conservation undertook a programme of research and conservation of a group of murals at The Church of St. James the Less, New Mills, Derbyshire. The murals were believed to have been executed by the Powell Brothers of Leeds using the Gambier Parry Spirit Fresco technique. This research is ongoing.Following an approved initial treatment proposal the conservation of the murals highlighted a few surprises, notably evidence of extensive over painting to all four in the past mimicking a faithful copy of the original design. This later layer was failing in areas revealing the original surface beneath. Samples were removed from one and examined by optical microscopy providing evidence for this and a reason for its failure. Research is ongoing to recreate a historically accurate Spirit Fresco to compare with the New Mills examples and other known examples in the UK. Little is currently known about this technique and a knowledge of the methods, materials and techniques used will provide valuable insight into the conservation methods and preservation of other frescos produced using this technique both here in the UK and elsewhere in Europe.Crick Smith reports are written for a range of clients, information is deliberately presented in a style that is easily accessible, technical terms are fully explained to enable understanding by a non-�?specialist reader, as it is understood that not all members of the client team may be experienced in understanding this type of investigation.
Conformer and pharmacophore based identification of peptidomimetic inhibitors of chikungunya virus nsP2 protease
Creators: name: Dhindwal, Sonali
name: Kesari, Pooja
name: Harvijay Singh
name: Pravindra Kumar
name: Shailly Tomar
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Chikungunya virus nsP2 replication protein is a cysteine protease, which cleaves the nonstructural nsP1234 polyprotein into functional replication components. The cleavage and processing of nsP1234 by nsP2 protease is essential for the replication and proliferation of the virus. Thus, ChikV nsP2 protease is a promising target for antiviral drug discovery. In this study, the crystal structure of the C-terminal domain of ChikV nsP2 protease (PDB ID: 4ZTB) was used for structure based identification and rational designing of peptidomimetic inhibitors against nsP2 protease. The interactions of the junction residues of nsP3/4 polyprotein in the active site of nsP2 protease have been mimicked to identify and design potential inhibitory molecules. Molecular docking of the nsP3/4 junction peptide in the active site of ChikV nsP2 protease provided the structural insight of the probable binding mode of nsP3/4 peptide and pigeonholed the molecular interactions critical for the substrate binding. Further, the shape and pharmacophoric properties of the viral nsP3/4 substrate peptide were taken into consideration and the mimetic molecules were identified and designed. The designed mimetic compounds were then analyzed by docking and their binding affinity was assessed by molecular dynamics simulations.
Investigation of the binding interactions of Bisdemethoxycurcumin, Diacetylcurcumin and Diacetylbisdemethoxycurcumin with bovine α-lactalbumin by experimental and theoretical analysis
Creators: name: Fakhrossadat Mohammadi
name: Moeeni, Marzieh
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: It was reported that bovine α-lactalbumin (BLA) as an important whey protein can be utilized as valuable vehicle for metal ions. The goal of this study was to investigate the interaction of BLA with bisdemethoxycurcumin (BDMC), Diacetylcurcumin (DAC), and diacetylbisdemethoxycurcumin (DABC) as three bioactive compounds by fluorescence quenching measurements and docking studies. It was observed that these ligands come closer to tryptophan residues and quench their emission without any change in their micro region polarity. The Stern–Volmer equation which is the best model to provide information about the interaction between small bioactive molecules and proteins was used to obtain the binding constants and the binding stoichiometry. Information about the extent of resonance energy transfer and Förster’s distance between donor and acceptor was estimated. Thermodynamic parameters confirmed that the final BDMC–BLA complex was stabilized by hydrogen bonds, whereas the final DABC–BLA and DAC–BLA complexes were stabilized by hydrophobic bonds which are in accordance with their chemical structures. Both the synchronous and docking studies verified that theTrp-26 which is the most exposed Tryptophan residue has the most contribution in the binding process. The Förster’s distances between bound ligands and tryptophans were in agreement with the measured distances by docking studies. The obtained achievements confirmed that there are considerable binding interactions between these curcuminoids and BLA.
Research and conservation of four spirit fresco mural at the Church of St. James the Less, New Mills, Derbyshire
Creators: name: Author, Unknown
Publisher: name: University of Lincoln
Year: 2024
Subjects: K250 - Conservation of buildings

description: In 2011 Crick Smith conservation undertook a programme of research and conservation of a group of murals at The Church of St. James the Less, New Mills, Derbyshire. The murals were believed to have been executed by the Powell Brothers of Leeds using the Gambier Parry Spirit Fresco technique. This research is ongoing.Following an approved initial treatment proposal the conservation of the murals highlighted a few surprises, notably evidence of extensive over painting to all four in the past mimicking a faithful copy of the original design. This later layer was failing in areas revealing the original surface beneath. Samples were removed from one and examined by optical microscopy providing evidence for this and a reason for its failure. Research is ongoing to recreate a historically accurate Spirit Fresco to compare with the New Mills examples and other known examples in the UK. Little is currently known about this technique and a knowledge of the methods, materials and techniques used will provide valuable insight into the conservation methods and preservation of other frescos produced using this technique both here in the UK and elsewhere in Europe.Crick Smith reports are written for a range of clients, information is deliberately presented in a style that is easily accessible, technical terms are fully explained to enable understanding by a non-�?specialist reader, as it is understood that not all members of the client team may be experienced in understanding this type of investigation.
Probing the binding mechanism of mercaptoguanine derivatives as inhibitors of HPPK by docking and molecular dynamics simulations
Creators: name: Parthiban Marimuthu
name: Kalaimathy Singaravelu
name: Vigneshwaran Namasivayam
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: 6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK) is a promising antimicrobial target involved in the folate biosynthesis pathway. Although, the results from crystallographic studies of HPPK have attracted a great interest in the design of novel HPPK inhibitors, the mechanism of action of HPPK due to inhibitor binding remains questionable. Recently, mercaptoguanine derivatives were reported to inhibit the pyrophosphoryl transfer mechanism of Staphylococcus aureus HPPK (SaHPPK). The present study is an attempt to understand the SaHPPK-inhibitors binding mechanism and to highlight the key residues that possibly involve in the complex formation. To decipher these questions, we used the state-of-the-art advanced insilico approach such as molecular docking, molecular dynamics (MD), molecular mechanics-generalized Born surface area approach. Domain cross correlation and principle component analysis were applied to the snapshots obtained from MD revealed that the compounds with high binding affinity stabilize the conformational dynamics of SaHPPK. The binding free energy estimation showed that the van der Waals and electrostatic interactions played a vital role for the binding mechanism. Additionally, the predicted binding free energy was in good agreement with the experimental values (R2 = .78). Moreover, the free energy decomposition on per-residue confirms the key residues that significantly contribute to the complex formation. These results are expected to be useful for rational design of novel SaHPPK inhibitors.
Raccontare il femminicidio: cronaca, tribunali, politiche. Blue paper della Ricerca PRIN-Miur 2015 «Rappresentazioni sociali della violenza sulle donne: il caso del femminicidio in Italia»
Creators: name: Lalli, Pina
name: Capelli, Claudia
name: Zingone, Michela
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2022
Subjects: SPS/08 Sociologia dei processi culturali e comunicativi

description: Il testo si propone di presentare in forma accessibile i principali risultati ottenuti da 5 gruppi di ricerca di altrettante Università italiane (Bologna, dove P. Lalli ha assolto un ruolo di coordinamento, Torino, Padova, Salento, Palermo) all’interno di un progetto Prin-Miur. Lavorando in stretta collaborazione, le diverse unità hanno analizzato il discorso pubblico sul femminicidio in tre diversi ambiti: la cronaca giornalistica, le sentenze giudiziarie, l’informazione e la comunicazione sulle politiche di contrasto. L’analisi completa è stata condotta nel volume a cura di P. Lalli, L’amore non uccide, pubblicato dalla società editrice il Mulino nel 2021 (con i contributi di: Marinella Belluati, Saveria Capecchi, Clara Cardella, Ilenia Colonna, Valentina Cremonesini, Stefano Cristante, Alessandra Dino, Chiara Gius, Gaetano Gucciardo, Tiziana Piccioni, Cosimo Marco Scarcelli, Renato Stella, Simona Tirocchi, Lorenzo Todesco e Michela Zingone). Qui si cerca invece di restituirne un resoconto a scopo divulgativo, utilizzando soprattutto immagini o infografiche. Una prima parte illustra sinteticamente le informazioni rilevate nella cronaca su 408 donne uccise per omicidio volontario in Italia tra il 1° gennaio 2015 e il 31 dicembre 2017. Nella seconda parte si offre una sintesi dei risultati ottenuti analizzando, da un lato, le notizie riguardanti l’omicidio «intimo» operato dal partner in 4 testate nazionali e, dall’altro, la cronaca locale sugli eventi di femminicidio nelle regioni Puglia e Veneto. La terza parte fa riferimento ai principali dati emersi dall’analisi di 370 sentenze emesse nel periodo 2010-2016 in relazione a 400 vittime femminili di omicidi commessi fra il 1975 e il 2015. Sono state anche qui ricostruite sinteticamente le principali informazioni riguardanti vittime, imputati, processi e modalità con cui si rileva siano trattati i moventi ritenuti attinenti alla «sfera sentimentale». La quarta parte riporta la sintesi dei risultati emersi dall’analisi relativa alla narrazione delle e nelle politiche con cui è trattato il fenomeno: dalla Commissione parlamentare di inchiesta sul femminicidio istituita per la prima volta nel 2017, alle notizie di cronaca su eventi, dati, manifestazioni sul femminicidio e a 46 campagne antiviolenza realizzate in Italia tra il 2006 e il 2018.
Roman military signalling on the North British Frontiers
Creators: name: Donaldson, G H
Publisher: name: Archaeology Data Service
Year: 2019

description: Archaeologia Aeliana, 13, 19-24
description: Considers criteria applicable to visual signalling; strategically, dispatch riders are more likely, and technically, acoustic signals (eg tuba, cornu) more effective. Suggests likely structures to look for.
The Location of the Siege Camp at Berwick-upon-Tweed, 1333
Creators: name: Shenton, Caroline
Publisher: name: Archaeology Data Service
Year: 2019

description: Archaeologia Aeliana, 29, 253-255
description: Identifies the location of the royal camp during the siege of Berwick, Northumberland, in AD1333, and in the process adds to knowledge of siege towns in the fourteenth century.
Two new triterpenoids from the roots of Pinus densiflora
Creators: name: Junnosuke Otaka
name: Masabumi Komatsu
name: Miyazaki, Yasumasa
name: Futamura, Yushi
name: Osada, Hiroyuki
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Chemical investigation of the roots of Pinus densiflora led to the isolation of two new triterpenoids, (24S)-3β-methoxy-24,25-epoxy-lanost-9(11)-ene (1) and 29-acetoxy-3α-methoxyserrat-14-en-21α-ol (2), together with three known serratene-type triterpenoids (3–5) and four known diterpenoids (6–9). Their structures were determined by spectroscopic analyses.
An excavation in Holy Island village, 1977
Creators: name: O'Sullivan, Deirdre Mary
Publisher: name: Archaeology Data Service
Year: 2019

description: Archaeologia Aeliana, 13, 27-116
description: Catalogues seven phases from Saxon or earlier domestic to later med and postmed stone structures; pottery 11th-20th century, first large publication for this area. Animal, fish, and bird remains (significant deep-water fishing); clay pipes, small finds.