cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Racial and insurance disparities in hospital referral and mortality for children undergoing congenital heart surgery
Creators: name: Chan, Titus
Publisher: name: University of Utah
Year: 2012
Subjects: Heart
Surgery
Mortality

description: Racial and insurance disparities have been documented in survival following congenital heart surgery. However, many studies used limited state or regional data. This study examines the impact of race and insurance status by applying a comprehensive risk-stratification system to two of the most recent national pediatric hospitalization  databases.  All admissions that fit a Risk Adjustment for Congenital Heart Surgery-1  (RACHS-1) category from the Kids' Inpatient Database (KID) 2003 and 2006 were  examined. Patient demographics and hospital characteristics were compared between  survivors and nonsurvivors as well as between insurance groups. Logistic regression  models examining hospital mortality, referral to high mortality hospitals, and emergent  admissions were constructed. Children with Medicaid insurance had increased odds of  mortality in 2003 (Odds Ratio 1.6, 95% Confidence Interval 1.2-2.1). In 2006, nonwhite  children had higher odds of mortality (Odds Ratio 1.4, 95% Confidence Interval 1.0-2.0).  When examining low mortality hospitals in 2006, where greater than 85% of children  received care, neither race nor insurance status were independently associated with  hospital mortality. However, in both years, children with Medicaid insurance and  nonwhite children were more likely to be emergently admitted to hospital for a cardiac  surgical procedure.  Hospital mortality disparities based on insurance status and race appear to  be improving. However, insurance and race continue to play a role in access to timely  pediatric cardiac services.
Sonnenfleckenzeichnung Nr. 23262.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.01.1970, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Antileishmanial activity of neo-clerodane diterpenes from Croton echioides
Creators: name: Novello, Cláudio Roberto
name: Düsman, Elisangela
name: Balbinot, Rodolfo Bento
name: de Paula, Jéssica Carreira
name: Nakamura, Celso Vataru
name: de Mello, João Carlos Palazzo
name: Sarragiotto, Maria Helena
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: Nowadays, new leishmanicidal drugs are needed and natural products arise as a promising alternative source. Therefore, bioguided fractionation of a hydroethanolic extract from the stem bark of Croton echioides Baill. were conducted based on its antileishmanial activity. Two novel neo-clerodane diterpenoids methyl-15,16-epoxy-3,13(16),14-neo-clerodatrien-17,18-dicarboxylate (1) and dimethyl-3-oxo-15,16-epoxy-13(16),14-neo-clerodadien-17,18-dicarboxylate (2) were isolated, as well as four known compounds (3–6) and lupeol, from the hexane fraction. Their structures were established by NMR analysis. The crude extract, fractions and the compounds (1 and 3–6) were evaluated for their in vitro antileishmanial activity and cytotoxicity against macrophages J774A.1. The selectivity index (SI) were calculated. The most active compound against promastigote forms of L. amazonensis was the clerodane diterpene 4, with IC50 values of 8.3 µM and SI value of 80.9. Our results highlighted stem bark of Croton echioides Baill. as a promising source for the development of a new chemotherapeutic agent to combat leishmaniasis.
Sonnenfleckenzeichnung Nr. 23254.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.01.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Leucothyreus amandus Ohaus 1918
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Leucothyreus
Leucothyreus amandus

description: Leucothyreus amandus Ohaus, 1918
Leucothyreus amandus Ohaus 1918a: 354 (French Guiana)
Distribution. French Guiana: Ohaus 1918a: 354; Blackwelder 1944: 248; Machatschke 1972: 348; Jameson and Hawkins 2005: 38; Soula 2010a: 59.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 124, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 23266.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.01.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Observations and modeling of thermally driven wind jets at the exit of a Utah canyon
Creators: name: Farley-Chrust, Morgan
Publisher: name: University of Utah
Year: 2012
Subjects: Canyon
Energy
Exit
Jets
Utah
Wind
Thermally driven winds
Weber Canyon

description: This thesis investigates summertime thermally driven wind circulations in a Utah canyon. The study is focused around Weber Canyon, Utah, which is a main tributary  canyon that feeds into the Great Salt Lake basin. A measurement campaign was conducted during July-September 2010 to observe and characterize the wind flow patterns in Weber Canyon and specifically the nature of the summertime fair-weather wind jet that has been observed to form at the exit region of Weber and other Utah canyons. This thesis research uniquely combines many meteorological data sources including existing automatic weather stations, measurement equipment borrowed from several generous parties, and equipment owned by the University of Utah's Atmospheric  Sciences department.  Winds within the canyon and at the exit exhibited a strong seasonal and diurnal variation that is linked to the yearly course of solar insolation. Strong nocturnal low-level wind jets formed on 75 of 90 nights (83%) at the Weber Canyon exit during the measurement campaign. Winds inside the canyon consisted of a weak but deep down valley flow layer that occupied most of the depth of the canyon. The flow was observed  to descend, thin and compress at the exit where winds were typically twice as strong as inside the canyon and much more shallow. Flow within the canyon and at the exit was influenced by the larger scale synoptic conditions. Clear skies and weak regional pressure  gradients along with light winds aloft were conducive to the development of strong canyon exit flows. Four canyon flow regimes were observed depending upon the strength and orientation of the synoptic flow. Observations of flow properties within and at the  exit of the canyon were compared to Large Eddy numerical simulations using the Advanced Research Weather Research and Forecast (ARW) numerical weather prediction (NWP) model developed by NCAR. Good agreement between the observations and model simulations has been achieved. The wind power potential at the exit region is shown to be excellent.
Leucothyreus anachoretus Erichson 1848
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Leucothyreus
Leucothyreus anachoretus

description: Leucothyreus anachoretus Erichson, 1848
Leucothyreus anachoreta Erichson 1848: 563 (Guyana)
Distribution. Guyana: Erichson 1848: 563 (as L. anachoreta); Jameson and Hawkins 2005: 38. “Guianas”: Blackwelder 1944: 248 (as L. anachoreta); Machatschke 1972: 348 (as L. anachoreta).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 124, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 23313.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.04.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23323.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.04.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt.  Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Are There the Impacts of Environmental Regulations on Manufacturing Export? Empirical Evidence from Chinese Manufacturing
Creators: name: Liu, Chenyue
name: Rumánková, Lenka
name: Liu, Chenyue
name: Rumánková, Lenka
Publisher: name: Unknown
Year: 2022
Subjects: subject: Environmental Economics and Policy
subject: Research Methods/ Statistical Methods
subject: environmental regulation
subject: Heckscher-Ohlin-Vanek model
subject: manufacturing export
subject: China
subject: pollution index

description: Environmental regulation is an effective tool to control environmental problems caused by foreign trade. Research conclusions are inconsistent on the relationship between environmental regulations and exports. Based on the Heckscher-Ohlin-Vanek model, this paper provides an empirical analysis for examination the effect of environmental regulations on manufacturing exports, adopting panel data of 16 sectors from China’s manufacturing during 2005-2015. Material capital, human capital, technology input and foreign direct investment are simultaneously selected as independent variables to explore the export impact of corresponding changes in these endowments. The pollution intensity index was introduced to categorise different manufacturing sectors. Results indicated that China’s environmental regulations intensity play different roles in the manufacturing sectors with different pollution levels. Stricter environmental regulation improves the export of intensive pollution manufacturing sectors but hinders exports in light pollution sectors. Meanwhile, other endowment factors also exert varying effects in the light, moderate and intensive pollution manufacturing sectors.
Adolescent and adult primiparous information needs and concerns regarding infant care.
Creators: name: Fisher, Deborah Darlene
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Nursing
subject: FOS: Health sciences
subject: Teenage Mothers

description: Traditionally postpartum infant care classes have been structured to meet the educational needs of the adult mother.  Due to the increasing number of pregnant adolescents, the educational needs of the adolescent mother must be assessed.  With this information postpartum infant care classes can then be structured to effectively assist the adolescent to assume her role of mother.  The goal of this descriptive study was to identify and compare infant care questions and concerns of adult and adolescent primiparous women.  Data obtained through questionnaires were analyzed in terms of the number and importance of infant care questions and concerns of the subject.  The comparing of demographic data revealed that more differences exist between the two groups than those solely based on age.  The first hypothesis, adolescent primiparous women would choose a significantly different number of questions and concerns' concerning infant care than adult primiparous women was statistically supported.  The adult mothers asked more questions than adolescent mothers, but the reason for the significant difference has not been uncovered.  Hypothesis II, adolescent primiparous mothers would have significantly different needs and concerns than adult mothers were not statistically supported.  The descriptive statistics did show that each group has specific questions and concerns they felt were more important.  The results of this study indicated a need for further study.  Recommendations were made in the deliverance of Nursing; care to adolescent mothers.
Enhancing Healthcare through Sensor-Enabled Digital Twins in Smart Environments: A Comprehensive Analysis
Creators: name: Adibi, Sasan
name: Rajabifard, A
name: Shojaei, D
name: Wickramasinghe, Nilmini
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 4606
subject: Distributed computing and systems software
classificationCode: 4608
subject: Human-centred computing
classificationCode: 4009
subject: Electronics, sensors and digital hardware
classificationCode: 4008
subject: Electrical engineering
classificationCode: 46
subject: Information and computing sciences
classificationCode: 4605
subject: Data management and data science

description: Abstract: This comprehensive review investigates the transformative potential of sensor-driven digital twin technology in enhancing healthcare delivery within smart environments. We explore the integration of smart environments with sensor technologies, digital health capabilities, and location-based services, focusing on their impacts on healthcare objectives and outcomes. This work analyzes the foundational technologies, encompassing the Internet of Things (IoT), Internet of Medical Things (IoMT), machine learning (ML), and artificial intelligence (AI), that underpin the functionalities within smart environments. We also examine the unique characteristics of smart homes and smart hospitals, highlighting their potential to revolutionize healthcare delivery through remote patient monitoring, telemedicine, and real-time data sharing. The review presents a novel solution framework leveraging sensor-driven digital twins to address both healthcare needs and user requirements. This framework incorporates wearable health devices, AI-driven health analytics, and a proof-of-concept digital twin application. Furthermore, we explore the role of location-based services (LBS) in smart environments, emphasizing their potential to enhance personalized healthcare interventions and emergency response capabilities. By analyzing the technical advancements in sensor technologies and digital twin applications, this review contributes valuable insights to the evolving landscape of smart environments for healthcare. We identify the opportunities and challenges associated with this emerging field and highlight the need for further research to fully realize its potential to improve healthcare delivery and patient well-being.
Leucothyreus crispinus Ohaus 1918
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Leucothyreus
Leucothyreus crispinus

description: Leucothyreus crispinus Ohaus, 1918
Leucothyreus crispinus Ohaus 1918a: 353 (Suriname)
Distribution. Suriname: Ohaus 1918a: 353; Blackwelder 1944: 248; Jameson and Hawkins 2005: 39; MHCN. French Guiana: Ohaus 1918a: 353; Blackwelder 1944: 248; Machatschke 1972: 349 (Kourou River Suriname [> French Guiana!]); Jameson and Hawkins 2005: 39; Soula 2010a: 59.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 124, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 23273.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.02.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Reproducing the Spanish Toxic Oil Syndrome in a murine model.
Creators: name: Salomoni, Martin A.
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology

description: Since the outbreak of the Spanish Toxic Oil Syndrome (TOS) in 1981, animal models have proven unsuccessful at reproducing the severity of this food-borne illness.  The intoxication was attributed to the ingestion of aniline-denatured repressed oil illegally sole as pure olive oil.  TOS was characterized by acute, subacute and chronic multi-system organ involvement including pulmonary dysfunction, server myalgias and intense peripheral eosinophilia.  Weight loss was commonly experienced by TOS patients.  In the experiments reported here, peripheral blood mononuclear cells (PBMC) from patients who suffered from TOS were injected intraperitoneally into immunodeficient mice.  The gamma-c/Rag2 KO mice were utilized to test the hypothesis that after reconstitution with human PBMC from TOS patients, followed by feeding of implicated oil, the TOS manifestations were to reproduced.  Four sets of negative controls were used: untreated mice, mice fed canola oil, mice reconstituted with PBMC from normal subjects and mice reconstituted with (normal or TOS) PBMC and fed canola oil    Following the immune reconstitution, mice were fed implicated or non-implicated oil for a period of 8 weeks.  At baseline, 4 and 8 week time points, peripheral blood counts were performed as well as measurement of plasma lactate dehydrogenase (LDH) and aspartate aminotranserase (AST) levels to assess organ damage.  All animals were screened for human IgG on week 4 to confirm PBMC engraftment.  Finally, on week 8, the major organs from each animal were harvested and examined for eosinophil infiltration and de-granulation by immunohistochemical staining to detect major protein (MBP) deposition.  The immune reconstitution of mice with human PBMC occurred 99% of the time (n=122).  Mice in the control groups failed to loose weight.  Generally, there was a steady increase of hematological markers from baseline to 8 weeks.  After the autopsy as week 8, 50% of the mice were screened for eosinophils and MBP deposition.  Only a rare number of eosinophils were found in the tissues, in the differential counts and in the peritoneal lavages, Overall, these results do not support the hypothesis that feeding toxic oil to mice reconstituted with TOS PBMC can reproduce the Spanish Toxic Oil Syndrome.
Use of Extracts from Nigerian Indigenous Plants as Staining Techniques in Bacteriology, Mycology and Histopathology
Creators: name: Ifeoma Enweani
Publisher: name: figshare
Year: 2020
Subjects: subject: 110801 Medical Bacteriology
subject: FOS: Health sciences

description: Dyestuffs from Nigerian plants were extracted and their staining ability on some species of bacteria, fungi and tissue biopses were determined. The study was carried out, to demonstrate the potential use of G. kola mesocarp, V. doniana fruit, L. aculaeta fruit, L. inermis leaf, C. ferrugnea fruit and P. soyauxii stem extracts as dyes/stains on Escherischia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus mirabilis, Candida albicans, Aspergillus niger and human appendix tissue. Fully automated Soxhlet solvent extraction technique was used for the extraction using ethanol and methanol. Solvent-Solvent fractionation technique was also, done to obtain purer form of the plants extracts using Ethylacetate, N-hexane and N-butanol as solvent. The simple stains like neutral red, lactophenol cotton blue and Haematoxylin & Eosin were used as positive controls for staining bacterial, fungi morphology and human appendix tissues respectively.
Bereavement in the elderly: spouse interaction as a modifying variable.
Creators: name: Attermeier, Mary Elizabeth
Publisher: name: University of Utah
Year: 2012
Subjects: Psychological
Aged

description: The purpose of this study in bereavement adaptation of the elderly was twofold.  First, the pre-terminal interaction between spouses was classified into two categories, closure and non-closure, by means of an index developed from a review of the literature.  This index quantified the type and extent of interaction between spouses when one spouse was dying.  Second, the group of survivors who attained closure was compared to those who did not attain closure in certain aspects of bereavement adaptation at two months after the death of the spouse.  The critical utilized were based on previously reported bereavement-related feelings and behaviors noted in other bereaved populations.  The survivor's perception of stressfulness of their spouse's death and their perceived coping ability was also compared between the two groups.  Closure had an affect on the intensity and frequency of feeling and behaviors.  In achieving closure, survivors had a chance to exercise certain behaviors which, in turn, paralleled certain feelings.  This initiated the mitigation process pre-terminally, which modified intense stimuli otherwise experienced during bereavement.  This investigations result illustrated this.  The repetitious review of the spouse's death, talking to and looking for the spouse became frustrating behavior that the survivor attempted to buffer by avoiding reminders of the spouse and keeping busy.  These behaviors related to feeling of disbelief, confusion, being dazed and irritable due to the nature of the disorientation with which the survivor was trying to cope.  The closure variable significantly contributed to the modification of these bewildering symptoms when their frequency or intensity was high.  Nursing; implications of this study were addressed to the three areas of research, practice, and education.
Immunobiology of murine lyme disease
Creators: name: Yang, Liming
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Epidemiology
subject: Immunology
subject: FOS: Clinical medicine

description: In the mouse model for Lyme disease developed by Dr. Barthold and colleagues, different inbred strains of mice reproducibly display mild, moderate and severe arthritis. C3H mice develop very severe arthritis with the infection of Borrelia burgdorferi and BALB/c mice develop mild arthritis. Previous reports from our laboratory demonstrated that B. burgdorferi possesses B-cell mitogenic and cytokine stimulatory activities in vitro. These activities were subsequently shown to be properties of the two major outer surface lipoproteins of B. burgdorferi, OspA and OspB. In this dissertation, mitogenic and inflammatory cytokine responses in B. burgdorferi infected C3H/HeJ and BALB/c strains of mice were investigated. Results demonstrated that infected C3H/HeJ mice displayed a persistent 10-fold increase in circulating IgG levels, a 2-fold increase in IgM levels, and a 15-fold increase in peripheral lymph node B cells. Interleukin-6 (IL-6) levels were found to be persistently elevated in serum of infected C3H/HeJ mice. In contrast, infected BALB/c mice had low level mitogenic activity and low levels of serum IL-6. These findings indicated that mitogen induced B cells and IL-6 may be involved in the pathogenesis of severe arthritis. In vivo neutralization of IL-6, TNF-alpha and IFN-gamma did not significantly alter the arthritis development. Bacterial invasion of tissues is an important aspect of Lyme disease. The intense inflammatory responses in C3H mice could be the result of greater numbers of spirochetes. Thus, it was necessary to develop a technique to reproducibly and accurately detect B. burgdorferi in mouse tissues. In this dissertation, a sensitive and quantitative PCR technique for the detection of spirochete DNA was developed. This dissertation has demonstrated a reproducible, quantitative difference in spirochete numbers in tissues of the two strains of mice. Ankles and hearts from C3H/HeJ mice were found to harbor 10-fold more B. burgdorferi DNA than the tissues from BALB/c mice. This difference in numbers of spirochetes correlated with the severity of arthritis in these two strains of mice. Furthermore, F1 mice infected with B. burgdorferi demonstrated severe arthritis and high levels of persisting spirochete numbers, similar to the C3H parents, indicating that the susceptibility to severe arthritis is a dominant trait and is associated with the high level of persisting spirochetes. These findings may allow the mapping of genes responsible for the development of arthritis.
Sonnenfleckenzeichnung Nr. 23283.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.02.1970, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Preferences of Small-Scale Farmers for Innovative Farming Techniques in Volcanic Highlands in Rwanda
Creators: name: Maniriho, Aristide
name: Musabanganji, Edouard
name: Mulumeoderhwa, Fidèle
name: Manirakiza, Dismas
name: Lebailly, Philippe
name: Maniriho, Aristide
name: Musabanganji, Edouard
name: Mulumeoderhwa, Fidèle
name: Manirakiza, Dismas
name: Lebailly, Philippe
Publisher: name: Unknown
Year: 2022
Subjects: Agribusiness
Environmental Economics and Policy
Research and Development/Tech Change/Emerging Technologies

description: This paper attempted to identify the determinant factors of innovative technologies preferences by small-scale farmers in the Volcanic Highlands in Rwanda. Data used were collected from a random sample of 401 small-scale crop producers using a structured questionnaire in the study area. A logit regression model was specified, whereby a binary maximum likelihood estimation method was used to identify the factors affecting of the adoption of chemical fertilizers, the determinants of the combined use of chemical and organic fertilizers, the determinants of the adoption of improved seeds, as well as the determinant factors of appropriate use of pesticides. The results showed that farmer’s education level, farming experience, membership to farm cooperative, the number of extension visits, and crop farming are the factors that affect positively the probability of adopting one or other of the four innovative farming techniques. From these results, we suggest the enhancement of extension services and other needed support to small-scale farmers (grants and subsidies, access to finance for example), the spread of professional trainings to farmers, and the increased farmers’ access to high-yielding seed varieties if farming professionalization and innovative farming techniques are still among the development goals.
Sonnenfleckenzeichnung Nr. 23320.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.04.1970, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Glucagon-like peptide-1 delivery for treatment of type 2 diabetes
Creators: name: Choi, Suna
Publisher: name: University of Utah
Year: 2012
Subjects: Insulinotropic
Hydrogel Formulation

description: Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone that increases insulin secretion in a glucose-dependent manner. Insulin secretion is only increased when concentrations of glucose is high and not at low to normal concentrations of glucose, therefore avoiding hypoglycemic episodes. In spite of its many remarkable advantages as a therapeutic agent for diabetes, GLP-1 is not immediately clinically applicable because of its extremely short half-life. The purpose of this research was to design an effective way of GLP-1 delivery for therapeutic use of GLP-1. The first half of the research studied the effects of GLP-1 delivery using a thermosensitive biodegradable triblock copolymer. The second half of this research was to design a new and effective GLP-1 delivery system for therapeutic use for type 2 diabetes treatment based upon construction of GLP-1 plasmid and its delivery. The effect of GLP-1 delivery system using biodegradable injectable polymer was studied. The results from the I release experiment did show steady amount of GLP-1 released from PLGA-PEG-PLGA triblock copolymer formulation with zinc-complexed GLP-1 depot more than ten days after loading. As a result from the animal experiment with the type 2 diabetic model, it was evident that the GLP-1 released from the thermosensitive biodegradable hydrogel formulation was bioactive as it stimulated insulin secretion in vivo. Therefore, it was concluded that it is feasible to use PLGA-PEG-PLGA triblock copolymer formulation with zinc-complexed GLP-1 as a 2 week delivery system, making it a twice-a-month injection depot. For less frequent and more convenient administration of GLP-1, the GLP-1 gene delivery system was attempted in this study. Since no reactive hypoglycemia occurs even with higher concentrations of GLP-1, a potent promoter/enhancer was used in this system. It has been established that GLP-1 gene delivery significantly decreased blood glucose levels in a type 2 diabetic animal model. The results showed that delivered GLP-1 gene stimulated insulin secretion, indicating that GLP-1 gene delivery also represents a promising candidate for treatment of type 2 diabetes.
Sonnenfleckenzeichnung Nr. 23276.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.02.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.01.1970, erstellt von Ahmet Topalbekiroğlu an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Leucothyreus dispar Burmeister 1844
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Leucothyreus
Leucothyreus dispar

description: Leucothyreus dispar Burmeister, 1844
Leucothyreus dispar Burmeister 1844: 498 (Columbien, am Orinoco [= Venezuela?, Colombia?])
Distribution. Guyana: Erichson 1848: 562. Venezuela: Burmeister 1844: 498 (?); Blackwelder 1944: 248; Machatschke 1972: 349; Jameson and Hawkins 2005: 40. Other: Burmeister 1844: 498 (Colombia?); Machatschke 1972: 349 (Colombia); Jameson and Hawkins 2005: 40 (Colombia).
Note. Erichson (1848: 562) mentions Leucothyreus dispar for Guyana, but we are unaware of any recent records of this species from the research area. We consider its occurrence there in need of confirmation.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 124, DOI: 10.5281/zenodo.3678492
Steroidal saponin from Agave marmorata Roezl modulates inflammatory response by inhibiting NF-κB and AP-1
Creators: name: A, Jonathan Cortés
name: Sánchez-Mendoza, Ernesto
name: Zamilpa, Alejandro
name: González-Cortazar, Manases
name: Herrera-Ruiz, Maribel
name: Almanza-Pérez, Julio Cesar
name: Terán-Cabanillas, Eli
name: Condé, Renaud
name: Domínguez-Ramírez, Lenin
name: Arcos, Elizur Montiel
name: Jiménez-Ferrer, Jesús Enrique
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Agave marmorata Roezl is an endemic succulent specie from the Oaxaca-Puebla area of Mexico. This plant is a medicinal recourse and contain a rich variety of saponins-type compounds with multiples biological effects. Some of them have been shown to be anticancer, antibacterial, or having anti-inflammatory and immunoregulation effects. This paper is the first scientific report to describe the pharmacological activity and chemistry of the saponin smilagenin-3-O-[β-D-glucopyranosyl (1→2)-β-D-galactopyranoside] (1), isolated from Agave marmorata Roezl. Saponin (1) displayed immunomodulating activity when assayed on cultured macrophages. It inhibits NO production (EC50 = 5.6 mg/ml, Emax = 101%), as well as NF-κB expression (EC50 = 0.086 mg/ml, Emax = 90%). Using bioinformatic molecular docking, we identified a new smilagenin- PI3K kinase interaction site.
The axon guidance molecule netrin is required in the quidance of dendrites and vascular endothelial gells.
Creators: name: Suli, Arminda
Publisher: name: University of Utah
Year: 2012
Subjects: Nervous System
Neurogenetics
Cardiovascular System

description: The biological question that interests me is: How do we make functional nervous and vascular systems? One of the first steps in this process is guiding neurons with their axons and dendrites, and vascular endothelial cells, toward the right places at the right times. To address the question of guidance, I have looked at Netrin, a guidance molecule known to be important in axonal guidance, and its role in guiding dendrites and vascular endothelial cells in vivo during zebrafish embryonic development. The dendritic guidance work has been done in the octavolateralis efferent system, which gives efferent input to the lateral line and ear and has pronounced dendrites that cross the midline. For the vascular work, I have concentrated on the development of the trunk vasculature and particularly on the formation of the parachordal vessel, a venous vessel that extends along the horizontal myoseptum and interconnects venous intersegmental vessels.  Chapter 1 is an introductory chapter in which I present the major questions I am trying to answer and the appropriate background on guidance, the octavolateralis efferent system, the vascular system, and Netrin signaling.  Chapter 2 is a peer-reviewed paper published in "The Journal of Neuroscience" in which I show that Netrin is important for the contralateral dendrites of the octavolateralis efferent neurons as they extend toward the midline.  Chapter 3 is a collaborative peer-reviewed paper published in the journal Science giving evidence that Netrin promotes angiogenesis, or sprouting of blood vessels from preexisting vessels, in vivo and in vitro. I contributed all of the zebrafish results.  Chapter 4 is written in the format of a peer-reviewed paper and shows the latest work I have done in finding the mechanism by which Netrin promotes parachordal vessel (PAV) formation. Finally, Chapter 5 (Conclusions) discusses the findings of this work and future directions.
Toxicity effect of sesquiterpene lactones from Jurinea gabrieliae bornm on mitochondria isolated from U87 cells
Creators: name: Atabaki, Vahideh
name: Seydi, Enayatollah
name: Hosseinabadi, Tahereh
name: Pourahmad, Jalal
name: Ramezani, Maral
name: Samiei, Fatemeh
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Sesquiterpene lactones (SLs) are a typical group of secondary metabolites in asteraceae family and well-known for their biologically potential in treatment of various diseases such as cancer and inflammation. Glioblastoma (GBM) is a most common brain malignancy in adults with poor prognosis. Finding phytochemicals with potential targeting mitochondria has been suggested as an important approach for many malignancies. In this study, we purified three guaianolide-type SLs, including 8-deacyloxy-8α-(methylacryloxy)-subluteolide (A), subluteolide (B) and janerin (C) from Jurinea gabrieliae Bornm by chromatography methods. Then, mitochondrial toxicity parameters were evaluated. All three SLs selectively inhibited SDH activity in mitochondria from U87 cells but not mitochondria from normal rat brain. In addition these SLs increased ROS formation and cytochrome c release and MMP collapse only in mitochondria from U87 cells but not normal rat neurons. Our results suggest that all three SLs may act as potential agents for future development in anti-glioma therapy.
Thin-film mixed-metal molecule-based magnets by chemical vapor deposition
Creators: name: Erickson, Preston Kaj
Publisher: name: University of Utah
Year: 2012
Subjects: Thin films
Molecule-based magnets
Chemical vapor deposition

description: A chemical vapor deposition method has been developed for the synthesis of both Co[TCNE]2 thin-films and VxCo1-x[TCNE]2 thin-films. Both materials have been  previously synthesized by various solution methods. The Co[TCNE]2 thin-films were characterized by infrared spectroscopy and magnetometer, and were determined to be identical in structure and magnetic behavior to the analogous solution-prepared samples.  VxCo1-x[TCNE]2, when prepared from solution, showed a composition dependence of the magnetic properties as well as the infrared characteristics. Higher  cobalt concentrations led to higher coercive fields with respect to V[TCNE]2, which has a coercive field of ~7 Oe at 5 K. At a composition of V0.3Co0.7[TCNE]2 the coercive field is ~270 Oe at 5 K. The thin-films of this material showed the same infrared characteristics, based on composition, as the solution-prepared compounds. There was, however, no increase in coercive field at any composition, with a maximum coercive field measured as 10 Oe for a composition of V0.45Co0.55[TCNE]2.
Sonnenfleckenzeichnung Nr. 23293.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.03.1970, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1970

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Microbial conversion of vanillin from ferulic acid extracted from raw coir pith
Creators: name: Rejani, Chalikkaran Thilakan
name: Radhakrishnan, Sivaramapillai
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Plant Biology

description: Coir pith, an agro-industrial residue, is resistant to natural degradation, and its accumulation causes environmental pollution. Ferulic acid, a precursor of vanillin, was extracted from the raw coir pith by chemical pre-treatment such as alkaline hydrolysis, acidification, and liquid–liquid extraction method. The obtained ferulic acid (1.2 g/50 g) was analysed using high-performance liquid chromatography (HPLC) and used as a substrate for biotransformation by Aspergillus niger to vanillic acid, which, in turn, was fermented by using Phanerochaete chrysosporium to vanillin. The quantity of vanillic acid detected by HPLC on the third day of incubation was 0.773 g/L, while the optimal yield of vanillin on the subsequent third day of incubation was 0.628 g/L. Thus, the chemical extraction of ferulic acid from coir pith ensued bioconversion into vanillin. These products are highly valuable and economical to be used in industries such as pharmaceuticals, health, cosmetics, and neutraceuticals.
Study Design Preregistration of the Post-Event Changes Study
Creators: name: Haehner, Peter
name: Luhmann, Maike
name: Schaumburg, Svenja
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Personality and Social Contexts
subject: Health Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: life events
subject: life satisfaction
subject: loneliness
subject: mental health
subject: personality traits
subject: self-esteem

description: In this preregistration, only the design of the Post-Event Changes Study (PEC-Study) will be preregistered. As the data collected in this study are intended to be used in different publications, the data analyses for these studies will be preregistered separately. The purpose of this study is to examine whether the perceptions of major life events predict post-event changes in mental health, life satisfaction, self-esteem, personality traits, maladaptive personality traits, affective well-being, and loneliness. For this purpose, we will longitudinally assess these constructs in participants who have recently experienced a major life event.