title: Ð¡ÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¼Ð¾Ð´Ð¸ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð±Ð¸Ð¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ½ÑÑ Ð¿Ð»ÑÐ½Ð¾Ðº Ð² Ð·Ð¾Ð½Ðµ Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ½Ð¾Ð³Ð¾ Ñ Ð¸ÑÑÑÐ³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ²Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Comparative analysis of the effectiveness of the use of modified biopolymer films in the area of a hardware surgical suture
Creators: name: ÐÐ¾Ð½ÑÐ°ÑÐ¾Ð²Ð°, ÐÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ½ÑÐ¹ ÑÐ¾Ð²
Ð½Ð°ÑÑÑÐµÐ½Ð¸Ðµ Ð³ÐµÑÐ¼ÐµÑÐ¸ÑÐ½Ð¾ÑÑÐ¸
Ð¼Ð¾Ð´Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ
Ð¿ÑÐ¾Ð´Ð¾Ð»ÑÐ½Ð°Ñ ÑÐµÐ·ÐµÐºÑÐ¸Ñ Ð¶ÐµÐ»ÑÐ´ÐºÐ°
Ð±Ð¸Ð¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ½ÑÐµ Ð¿Ð»ÑÐ½ÐºÐ¸
ÑÐ¾Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑ Ð»Ð°ÐºÑÐ¸Ð´Ð° Ñ Ð³Ð»Ð¸ÐºÐ¾Ð»Ð¸Ð´Ð¾Ð¼
Ñ Ð¸ÑÐ¾Ð·Ð°Ð½
Ñardware seam
violation of tightness
Ñhitosan
modification
longitudinal resection of the stomach
postoperative scar
biopolymer films
efficiency
a copolymer of lactide with glycolide

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description: This work is devoted to a comparative analysis of the effectiveness of using modified biopolymer films in the area of a surgical surgical suture in the conditions of its failure on the model of longitudinal gastrectomy. To accomplish the goal and objectives of the study, the experiment used histological, histochemical and morphometric methods. In this work, to solve the problems posed, we used methods such as histological processing of the material with the necessary organs of the laboratory animals for the experiment, making histological sections and staining, namely hematoxylin-eosin staining and Masson staining. The morphometry method necessary for the analysis of histological examination data was also used. In the course of the study, an experimental model of a leak in the hardware seam was developed and implemented to assess the effectiveness of biopolymer films. The model was verified by the results of a histological examination, during which various pathological changes in the tissues were determined. Based on the results obtained, the optimal time interval for the animals to withdraw from the experiment was determined (from 7 to 20 days). At the next stage of work, in conditions of a leak in the hardware suture, various types of modified biopolymer films were used on the model of the operation of longitudinal gastrectomy. Morphological changes in tissues were described in detail and a comparative evaluation of the effectiveness of the use of modified biopolymer films was carried out (based on the severity of morphological changes). Films were determined from the experimental samples, which proved to be more effective in comparison with other samples: 3b, I-150, I-270. The results of the study can be used to improve the types of modified films based on biodegradable polymers developed for the prevention of insolvency of a surgical hardware suture.