cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Exploring the potential mechanism of Chinese herbal medicine Fuzi on aplastic anemia based on UHPLC-MS/MS method combined with network pharmacology and molecular docking
Creators: name: Wei, Wenjian
name: Si, Yuping
name: Li, Zonghong
name: Yin, Xuewei
name: Ma, Guodong
name: Shi, Jingbo
name: Li, Changnian
name: Yu, Liming
name: Zheng, Wei
name: Wang, Yan
name: Liu, Kui
name: Xu, Ruirong
name: Cui, Siyuan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: To reveal the potential mechanism of the effect of Chinese Herbal Medicine Fuzi on Aplastic anaemia (AA) according to the network pharmacology approach and molecular docking. According to Ultra High Performance Liquid Chromatography Mass Spectrometry (UHPLC-MS/MS), 146 chemical ingredients of Fuzi were obtained. By SwissADME online system analysis, a total of 55 compounds such as Magnoflorine, Scutellarein, Luteolin and Gingerol may be the main active components of Fuzi and 145 common targets related to AA were predicted. 17 targets such as MAPK1, AKT1 and GRB2 were considered as hub targets. KEGG and GO enrichment analysis obtained 122 signalling pathways and 950 remarkable results. These results suggested that Fuzi exerted pharmacological effects on AA mainly by regulating PI3K-Akt, MAPK and JAK-STAT signalling pathways and epithelial cell proliferation, cell differentiation, regulate energy production and other biological processes. Meanwhile, molecular docking results showed that the hub targets had good binding ability with the main active ingredients.
title: La resonancia magnética en el carcinoma de cérvix uterino.
Creators: name: González Ibáñez, Sandra Emilia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Genital / Reproductive system female
subject: MR

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Conocer algunos aspectos del cáncer de cérvix como la frecuencia e incidencia,
lostipos histopatológicos,
losfactores predisponentes,
la presentación clínica,
el diagnóstico precoz y laestadificación de la FIGO (Federación Internacional de...
Canadian musique: English to French translation in contemporary Canadian music
Creators: name: Locke, Sharon
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Education, Bilingual and Multicultural.
subject: Music.

description: This thesis examines translation in English Canadian music of the late 20th/early 21st century and the challenges unique to song translation. It first explores this increasingly apparent trend in the light of Canadian Radio-television and Telecommunications Commission (CRTC) regulations, and then studies the history and background of Canadian music. It then looks at song translation as a form of poetry translation, to study the challenges faced in the process and the solutions found, focussing specifically on the translation of various poetic devices used in the corpus. Further, it examines the intentions that generate these translations and seeks to analyze the finished products in the light of these motivations. Do musical groups translate their work in order to expand their horizons and explore another culture, or do they do so primarily to expand the fan base and generate more revenue? And what methods are used to deal with all the inherent restrictions of song translation? What does the finished product tell the listener about the intention of the translation?
The unitary group as an invariant of a simple unital C*-algebra
Creators: name: Al-Rawashdeh, Ahmed
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Mathematics.

description: In 1954, H. Dye proved that the unitary groups of von Neumann factors not of type I2n determine the algebraic type of factors. Using Dye's result, M. Broise showed that any isomorphism between the unitary groups of two von Neumann factors not of type In is implemented by a linear or a conjugate linear *-isomorphism between the factors. Using Dye's approach, A. Booth proved that two simple unital AF-algebras are isomorphic if and only if their unitary groups are (algebraically) isomorphic. In the first part of this thesis, we extend Booth's result to a larger class of amenable unital C*-algebras. If ϕ is an isomorphism between the unitary groups of two unital C*-algebras, it induces a bijective map &thgr;ϕ between the sets of projections of the algebras. For some UHF-algebras, we construct an automorphism ϕ of their unitary group, such that &thgr;ϕ does not preserve the orthogonality of projections. For a large class of unital C*-algebras, we show that &thgr;ϕ is always an orthoisomorphism. This class includes in particular the Cuntz algebras On , 2 ≤ n ≤ infinity, and the simple unital AF-algebras having 2-divisible K0-group. If ϕ is a continuous automorphism of the unitary group of a UHF-algebra A, we show that ϕ is implemented by a linear or a conjugate linear *-automorphism of A.
title: Sarcoma sinovial.Hallazgos radiológicos
Creators: name: Molina Zuluaga, Jairo
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Outcomes analysis
subject: MR
subject: Trauma
subject: Soft tissues / Skin
subject: Musculoskeletal soft tissue

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
OBJETIVOS DE APRENDIZAJE: Describir el espectro radiológico del sarcoma sinovial,
con énfasis especial en los hallazgos que aporta la resonancia magnética. Destacar los hallazgos más característicos de este tumor y documentar formas de...
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
Creators: name: Jensen, Maj-Britt
name: Lænkholm, Anne-Vibeke
name: Nielsen, Torsten
name: Eriksen, Jens O.
name: Wehn, Pernille
name: Hood, Tressa
name: Ram, Namratha
name: Buckingham, Wesley
name: Ferree, Sean
name: Ejlertsen, Bent
Publisher: name: BioMed Central
Year: 2018

description: Background: The PAM50-based (Prosigna) risk of recurrence (ROR) score and intrinsic subtypes are prognostic for women with high-risk breast cancer. We investigate the predictive ability of Prosigna regarding the effectiveness of cyclophosphamide-based adjuvant chemotherapy in premenopausal patients with high-risk breast cancer. Methods: Prosigna assays were performed on the NanoString platform in tumors from participants in Danish Breast Cancer Group (DBCG) 77B, a four-arm trial that randomized premenopausal women with high-risk early breast cancer to no systemic treatment, levamisole, oral cyclophosphamide (C) or cyclophosphamide, methotrexate and fluorouracil (CMF). Results: In total, this retrospective analysis included 460 women (40% of the 1146 randomized patients). The continuous Prosigna ROR score was prognostic in the no systemic treatment group (unadjusted P < 0.001 for disease-free survival (DFS), P = 0.001 for overall survival (OS)). No statistically significant interaction of continuous ROR score and treatment on DFS and OS was found. A highly significant association was observed between intrinsic subtypes and C/CMF treatment for DFS (Pinteraction = 0.003 unadjusted, P = 0.001 adjusted) and OS (Pinteraction = 0.04). In the adjusted analysis treatment with C/CMF was associated with a reduced risk of DFS events in patients with basal-like (hazard ratio (HR) 0.14; 95% CI 0.06; 0.32) and luminal B (HR 0.48; 95% CI 0.27; 0.84) subtypes but not in patients with Human epidermal growth factor receptor-enriched (HR 1.05; 95% CI 0.56; 1.95) or luminal A (HR 0.61; 95% CI 0.32; 1.16) subtypes. Conclusion: The Prosigna ROR score and intrinsic subtypes were prognostic in high-risk premenopausal patients with breast cancer, and intrinsic subtypes identify high-risk patients with or without major benefit from adjuvant C/CMF treatment.
Energiemonitoring – Dashboard (Factsheet)
Creators: name: NEFI New Energy for Industry
Publisher: name: NEFI
Year: 2024
Subjects: NEFI
Innovationsnetzwerk
Energie
Industrie
New Energy for Industry
Klima- und Energiefonds
Vorzeigeregion
Prognosetool
Seilbahnunternehmen
Skigebiet
Monitoring

description: Durch kontinuierliche Überwachung und Prognose des Energieverbrauchs kann die Effizienz des gesamten Systems gesteigert und der Anteil erneuerbarer Energien erhöht werden, was zu einer Verringerung der CO₂-Emissionen führt. Die Erkennung von Lastspitzen ermöglicht zudem eine kosteneffiziente und präzise Planung des Anlageneinsatzes, beispielsweise in der stromintensiven Beschneiuungssaison von Schigebieten.
title: "My Virtual Dream"
title: Collective Neurofeedback in an Immersive Art Environment
titleType: Subtitle
Creators: name: Kovacevic, Natasha
name: Ritter, Petra
name: Tays, William
name: Moreno, Sylvain
name: McIntosh, Anthony Randal
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: While human brains are specialized for complex and variable real world tasks, most neuroscience studies reduce environmental complexity, which limits the range of behaviours that can be explored. Motivated to overcome this limitation, we conducted a large-scale experiment with electroencephalography (EEG) based brain-computer interface (BCI) technology as part of an immersive multi-media science-art installation. Data from 523 participants were collected in a single night. The exploratory experiment was designed as a collective computer game where players manipulated mental states of relaxation and concentration with neurofeedback targeting modulation of relative spectral power in alpha and beta frequency ranges. Besides validating robust time-of- night effects, gender differences and distinct spectral power patterns for the two mental states, our results also show differences in neurofeedback learning outcome. The unusually large sample size allowed us to detect unprecedented speed of learning changes in the power spectrum (~ 1 min). Moreover, we found that participants' baseline brain activity predicted subsequent neurofeedback beta training, indicating state-dependent learning. Besides revealing these training effects, which are relevant for BCI applications, our results validate a novel platform engaging art and science and fostering the understanding of brains under natural conditions.
Drive to football? Take your kids to the pool? You’re probably emitting an astonishing amount of CO2
Creators: name: Breitbarth, Tim
name: Karg, Adam
name: Symons, Kasey
Publisher: name: Swinburne
Year: 2024

description: Few people would stop to consider if their sporting activities damage the environment. But our research shows Victorians use a huge chunk of their "personal carbon budget" driving to and from sport events each year - either to watch or participate, or to transport children...
Detection of ground moving objects with synthetic aperture radar
Creators: name: Sikaneta, Ishuwa C
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Engineering, Electronics and Electrical.

description: This thesis investigates Ground Moving Target Indication (GMTI) using a multi-aperture Synthetic Aperture Radar (SAR). GMTI relevant methods to process the SAR data collected from a strip-map system are presented. Techniques for mitigation of processing ambiguities are proposed, and a map-drift based automatic focus algorithm for the moving targets is developed. Target detectors based on the multi-channel covariance matrix are presented. Comparisons of the proposed detectors with classical methods, such as Displaced Phase Centre Antenna (DPCA), or Along Track Interferometry (ATI), show increased capability in non-ideal terrain types. By decomposing the complex Wishart probability distribution of the covariance matrix into probability distributions of the eigenvalues and eigenvectors, we derive the receiver operating characteristics (ROCs) of the new detection metrics in ideal terrain. The complete analysis is presented for a two-channel system as well as for special cases of the three-channel system. Finally, since implementation of the Constant False Alarm Rate (CFAR) detectors using the new metrics requires estimation of the local scene parameters, a new parameter estimation method is presented. This parameter estimation technique suggests an extension of the current statistical model of the SAR data; an extension that is also examined.
Genome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity
Creators: name: Winter, Sebastian Virreira
name: Zychlinsky, Arturo
name: Bardoel, Bart W.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Staphylococcus aureus causes a wide variety of infections and antibiotic resistant strains are a major problem in hospitals. One of the best studied virulence factors of S. aureus is the pore-forming toxin alpha hemolysin (αHL) whose mechanism of action is incompletely understood. We performed a genome- wide loss-of-function screen using CRISPR/Cas9 technology to identify host targets required for αHL susceptibility in human myeloid cells. We found gRNAs for ten genes enriched after intoxication with αHL and focused on the top five hits. Besides a disintegrin and metalloproteinase domain-containing protein 10 (ADAM10), the host receptor for αHL, we identified three proteins, Sys1 golgi trafficking protein (SYS1), ADP-ribosylation factor 1 (ARFRP1), and tetraspanin-14 (TSPAN14) which regulate the presentation of ADAM10 on the plasma membrane post-translationally. Interestingly, we also showed that cells lacking sphingomyelin synthase 1 (SGMS1) resist αHL intoxication, but have only a slightly reduced ADAM10 surface expression. SGMS1 regulates lipid raft formation, suggesting that αHL requires these membrane microdomains for attachment and cytotoxicity.
The relationship between star formation activity and galaxy structural properties in CANDELS and a semi-analytic model
Creators: name: Brennan, Ryan
name: Pandya, Viraj
name: Somerville, Rachel S.
name: Barro, Guillermo
name: Bluck, Asa F.L.
name: Taylor, Edward
name: Wuyts, Stijn
name: Bell, Eric F.
name: Dekel, Avishai
name: Faber, Sandra
name: Ferguson, Henry C.
name: Koekemoer, Anton M.
name: Kurczynski, Peter
name: McIntosh, Daniel H.
name: Newman, Jeffrey A.
name: Primack, Joel
Publisher: name: Swinburne
Year: 2024

description: We study the correlation of galaxy structural properties with their location relative to the SFR- M* correlation, also known as the star formation 'star-forming main sequence' (SFMS), in the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey and Galaxy and Mass Assembly Survey and in a semi-analytic model (SAM) of galaxy formation. We first study the distribution of median Sérsic index, effective radius, star formation rate (SFR) density and stellar mass density in the SFR-M* plane.We then define a redshift-dependent main sequence and examine the medians of these quantities as a function of distance from this main sequence, both above (higher SFRs) and below (lower SFRs). Finally, we examine the distributions of distance from the main sequence in bins of these quantities. We find strong correlations between all of these galaxy structural properties and the distance from the SFMS, such that as we move from galaxies above the SFMS to those below it, we see a nearly monotonic trend towards higher median Sérsic index, smaller radius, lower SFR density, and higher stellar density. In the SAM, bulge growth is driven by mergers and disc instabilities, and is accompanied by the growth of a supermassive black hole which can regulate or quench star formation via active galactic nucleus feedback.We find that our model qualitatively reproduces the trends described above, supporting a picture in which black holes and bulges co-evolve, and active galactic nucleus feedback plays a critical role in moving galaxies off of the SFMS.
Breakfast in Canada: Prevalence of Consumption, Contribution to Nutrient and Food Group Intakes, and Variability across Tertiles of Daily Diet Quality. A Study from the International Breakfast Research Initiative
Creators: name: Barr, Susan I.
name: Vatanparast, Hassan
name: Smith, Jessica
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: This study used 24-h recall data from the nationally representative 2015 Canadian Community Health Survey-Nutrition to assess breakfast intake among Canadians aged 6–12 years (n = 2331), 13–17 years (n = 2026), 18–54 years (n = 7651), and 55+ years (n = 6279). Overall, 90% consumed breakfast; breakfast consumers reported higher intakes of energy and key nutrients and had higher daily diet quality scores assessed using the Nutrient-Rich Foods Index 9.3 (NRF 9.3). Among breakfast consumers (n = 16,484), breakfast contributed a mean of 389 kcal (1628 kJ) and 21.6% of daily energy intake. Relative to its contribution to energy, breakfast contributed higher intakes of fruit, whole grains, and fluid milk, as well as associated nutrients (e.g., carbohydrate, total sugars, fiber, calcium, and vitamin D). Among breakfast consumers classified by daily dietary quality (NRF 9.3 score), energy intake at breakfast did not differ across tertiles for either children or adults. However, intakes of key nutrients, fiber, and total sugars increased across tertiles, and among adults, intakes of saturated fat and sodium decreased. Mean intakes of fruit, whole grains, and fluid milk also increased across tertiles, as did the proportion of individuals consuming these foods; higher fruit and milk intakes may explain higher sugar intakes as diet quality increased. Promoting the consumption of these foods at breakfast could contribute to improved diet quality among Canadians.
Four selected high molecular weight heterocyclic aromatic hydrocarbons: Ecotoxicological hazard assessment, environmental relevance and regulatory needs under REACH
Creators: name: Brendel, Stephan
name: Einhenkel-Arle, Doreen
name: Hassold, Enken
name: Polleichtner, Christian
Publisher: name: My University
Year: 2018
Subjects: Ökotoxizität

description: Little is known about the ecotoxicity of heterocyclic aromatic hydrocarbons (NSO-HETs) to aquatic organisms. In the environment, NSO-HETs have been shown to occur in a strong association with their unsubstituted carbocyclic analogues, the polycyclic aromatic hydrocarbons (PAH), for which much more information is available. The present study addressed this issue by investigating the toxicity of four selected NSO-HETs in green algae (Desmodesmus subspicatus), daphnids (Daphnia magna) and fish embryos (Danio rerio). The four high molecular weight NSO-HETs dibenz[a,j]acridine (DBA), 7H-dibenzo[c,g]carbazole (DBC), benzo[b]naphtho[2,1-d]thiophene (BNT) and benzo[b]naphtho[1,2-d]furan (BNF) were selected, based on the results of a previous research project, indicating a lack of toxicity data and a high potential for persistence and bioaccumulation. The solubilities of the NSO-HETs in the test media were determined and turned out to be comparatively low (2.7-317ng/L) increasing in the following order: DBA < BNT " DBC " BNF. Exposure concentrations during the toxicity tests were quantified with GC-MS and decreased strongly possibly due to sorption or metabolising during the test periods (48-96 h). Therefore, the estimated effect concentrations were related to the mean measured concentrations, as endpoints related to nominal concentrations would have underestimated the toxicity many times over. Within the range of the substance solubilities, BNF affected all test organisms with fish embryos being the most sensitive (fish: EC50 6.7 ng/L, algae: EC10 17.8 ng/L, daphnids: EC50 55.8 ng/L). DBC affected daphnids (EC50 2.5 ng/L,) and algae (EC10 3.1 ng/L), but not fish embryos. The lowest toxicity endpoint was observed for BNT affecting only algae (NOEC 0.556 ng/L) and neither daphnids nor fish embryos. DBA did not show any effects on the tested organisms in the range of the water solubility. However, we would expect effects in long-term toxicity studies to fish and aquatic invertebrates for all substances at lower concentrations, which needs further investigation. All four NSO-HETs were identified in mussels (Mytilus edulis) from the German coasts, in green kale (Brassica oleracea var. acephala) and in freshwater harbor sediment in concentrations between 0.07 and 2 ng/kg, highlighting their relevance as environmental contaminants. There is a need to regulate the four NSO-HETs within the REACH regulation due to their intrinsic properties and their environmental relevance. However, acquisition of additional experimental data appears to be pivotal for a regulation under REACH. © 2018 The Authors. Published by Elsevier Inc.
What does sociocultural learning and literacy look like in an adult employment preparation program?
Creators: name: Pinsent-Johnson, Christine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Education, Adult and Continuing.
subject: Education, Reading.

description: The closely aligned theoretical discussions of situated learning (Lave & Wenger, 1991; Wenger, 1998) and situated literacy (Barton & Hamilton, 1998; Hamilton, 2000) were used to explore literacy and learning activities in an adult literacy program that combined literacy education and employment preparation in three distinct learning settings. The parallel discussions provided a socioculturally-based framework that permitted a detailed analysis of what learning and literacy looked like. Guiding the study was the following question: How do situated views of literacy and learning contribute to an understanding of the employment preparation program and its three settings? Using the frameworks of situated learning and literacy to closely examine the employment preparation program revealed disconnects between the work settings (the coffee shop and job placements) and the class setting, and subsequently between the notions of learning literacy and learning about work. Among the study's contributions is a clearer conceptualization of a broad definition of literacy, in which the development of literacy practices becomes the focus for supporting the development of adult literacy education. Policy contributions examine the role of the provincial program funder and how it has a structure to support the development of a practice-based approach in adult literacy education. Finally, contributions to research propose the use of an analytical tool to further understand sociocultural learning, and specifically literacy and learning practices, in adult literacy programs. (Abstract shortened by UMI.)
Rethinking Accountability: Making Canadian Democracy Work Toward an Interactive and Ethical Public Space
Creators: name: Teleki, Paul
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Philosophy.
subject: Political Science, General.

description: Canadian Westminster democracy is representational and problematic because it maintains accountability structures at the bureaucratic and hierarchical level from the top-down. This results in the exclusion of citizens from the accountability process and a public service and government that makes decisions that mayor may not represent the citizenry. Broadening the democratic context to promote inclusivity, through participatory and deliberative democratic theory, will provide the space for an ethical and active accountability to flourish. Philosophically justifying the need to transition from our current accountability regime to include Alan Gewirth's conception of the community of rights (1996) will make political leaders ethically obliged to effectuate citizen preferences in political processes. By establishing the moral obligation of political leaders to effectively engage citizens in political processes, there must be a discussion of the actual policies and procedures that could guide the process of effectuating citizen preferences. We suggest that information and communication technologies in conjunction with face-to-face consultations may provide a conduit for the successful integration of citizen preferences, thereby resulting in an interactive democratic context which facilitates active accountability for citizens.
Understanding Goal-Related Tensions within Australian Environmental Social Enterprises
Creators: name: Scott, Adam Douglas
Publisher: name: Swinburne
Year: 2024

description: In light of worsening global environmental conditions, environmental social enterprises (ESEs) have been lauded as “sustainable alternatives” to traditional business because creating environmental value is their primary or joint purpose. However, due to the simultaneous pursuit of profit and environmental value, ESEs may experience goal-related tensions, preventing them from achieving their stated purposes. This thesis demonstrates that systems theory can be a useful lens to help understand the emergence and management of tensions. It also has practical implications for organisations pursuing sustainability by demonstrating empirically driven practices that may lead to improved sustainability outcomes.
Research report: Computational Biochemistry (2011 - 2016)
Creators: name: Korth, Martin
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Theoretische Chemie, Lebenswissenschaften
subject: Universities; Germany; Ulm
subject: Research Ulm
subject: DDC 540 / Chemistry & allied sciences
subject: Universities and colleges; Germany
subject: Theoretical chemistry; Research
subject: Biosciences; Research
subject: Universität Ulm
subject: Theoretische Chemie
subject: Biowissenschaften
subject: Forschung

description: Forschungsbericht der Barbara-Mez-Starck-Stiftungsprofessur; Projekte mit Bezug zu den Lebenswissenschaften
The role of Hoxa7 and Pax8 in epithelial ovarian cancer differentiation
Creators: name: Pitre, Elizabeth
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Biology, Molecular.

description: Epithelial ovarian cancer (EOC) is divided into several histological subtypes characterized by Mullerian-like differentiation and the expression of genes not expressed in normal ovarian surface epithelium. Many of these genes are implicated in female reproductive tract development, including Hoxa7 and Pax8, and it has been proposed that these genes are involved in the differentiation and progression of EOC. The effects of Hoxa7 overexpression (cellular proliferation, morphology, expression of E-cadherin and vimentin) were investigated in cell lines derived from our transgenic mouse models of ovarian cancer. However, Hoxa7 overexpression did not significantly affect any of these parameters. Immunohistochemical analysis revealed that Pax8 often appears to be localized to regions of papillary differentiation in tumours from transgenic tgMISIIR-TAg mice. These results suggest that while Hoxa7 alone does not drive EOC differentiation in vitro, expression of Pax8 may contribute to the differentiated epithelial features of ovarian cancer.
Lifetime prevalence of mental disorders among first and second generation individuals with Turkish migration backgrounds in Germany
Creators: name: Dingoyan, Demet
name: Schulz, Holger
name: Kluge, Ulrike
name: Penka, Simone
name: Vardar, Azra
name: Von Wolff, Alessa
name: Strehle, Jens
name: Wittchen, Hans-Ulrich
name: Koch, Uwe
name: Heinz, Andreas
name: Moesko, Mike
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Mental disorder
subject: Prevalence
subject: Migration
subject: Turkish Composite
subject: International Diagnostic Interview (CIDI)
subject: 100 Philosophie und Psychologie::150 Psychologie
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::304 Das Sozialverhalten beeinflussende Faktoren

description: Background This paper focuses on the lifetime prevalence of mental disorders in individuals with Turkish migration backgrounds in Germany, as there is a lack of reliable epidemiological data on this subject. Methods In total, 662 adults with Turkish migration backgrounds were interviewed in Hamburg and Berlin by trained, bilingual interviewers using the computerized Composite International Diagnostic Interview (CIDI DIA-X Version 2.8) to assess diagnoses according to the DSM-IVTR. Results The analyses showed a weighted lifetime prevalence of 78.8% for any mental disorder, 21.6% for more than one and 7.3% for five or more disorders. Any mood disorder (41.9%), any anxiety disorder (35.7%) and any somatoform disorder/syndrome (33.7%) had the highest prevalences. Despite the sociodemographic differences between the first and second generations, there were no significant differences in the lifetime prevalence between generations, with the exception of any bipolar disorder. Female gender, older age and no current partnership were significantly associated with the occurrence of any mood disorder. Conclusions Overall, the results indicate a high lifetime prevalence in individuals with Turkish migration backgrounds in Germany. These initial data are highly relevant to the German clinical and psychosocial healthcare system; however, the methodological limitations and potential biases should be considered when interpreting the results.
Kohlenwasserstoffe sicher als Kältemittel einsetzen - Entwicklung einer Strategie zum vermehrten Einsatz von Kohlenwasserstoff-Kältemitteln als Beitrag zum deutschen Klimaschutzziel unter Berücksichtigung des Energieziels 2050
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2014
Subjects: subject: Klima
subject: Kohlenwasserstoff
subject: Kältemittel
subject: Klimaschutzziel
subject: Klima | Energie
subject: Climate | Energy

description: In der vorliegenden Studie wird eine Strategie vorgeschlagen, mit der in Deutschland ein breiterer Einsatz von Kohlenwasserstoffen als Kältemittel erreicht werden könnte. Vier Hauptanwendungen wurden hierfür aus den vielfältigen Anwendungen in derKlima- und Kältetechnik ausgewählt. Sogenannte "Schwellentechnologien" wurden bevorzugt ausgewählt, d. h. Technologien die grundsätzlich mit keinem zusätzlichen bzw. nur relativ geringem zusätzlichem Forschungs- und Entwicklungsbedarf marktfähig sind, sich bisher jedoch noch nicht etablieren konnten. Die vier ausgewählten Hauptanwendungen sind Raumklimageräte, Haushaltswärmepumpen (zum Heizen), Kühl-Lkw und Flüssigkeitskühlsätze (bis 1 MW). Kriterien für die Auswahl der Hauptanwendungen waren ihre Bedeutung in Bezug auf die Kältemittelemissionen in Deutschland, die technisch mögliche Marktdurchdringung der Kohlenwasserstoff-Technik im Jahr 2030, ihre Marktentwicklung und die daraus resultierende Einschätzung zukünftiger Chancen für Kohlenwasserstoff-Technologien.
Quelle: www.umweltbundesamt.de

description: In der vorliegenden Studie wird eine Strategie vorgeschlagen, mit der in Deutschland ein breiterer Einsatz von Kohlenwasserstoffen als Kältemittel erreicht werden könnte. Vier Hauptanwendungen wurden hierfür aus den vielfältigen Anwendungen in der ⁠Klima⁠- und Kältetechnik ausgewählt. Sogenannte „Schwellentechnologien“ wurden bevorzugt ausgewählt, d. h. Technologien die grundsätzlich mit keinem zusätzlichen bzw. nur relativ geringem zusätzlichem Forschungs- und Entwicklungsbedarf marktfähig sind, sich bisher jedoch noch nicht etablieren konnten. Die vier ausgewählten Hauptanwendungen sind Raumklimageräte, Haushaltswärmepumpen (zum Heizen), Kühl-Lkw und Flüssigkeitskühlsätze (bis 1 MW). Kriterien für die Auswahl der Hauptanwendungen waren ihre Bedeutung in Bezug auf die Kältemittelemissionen in Deutschland, die technisch mögliche Marktdurchdringung der Kohlenwasserstoff-Technik im Jahr 2030, ihre Marktentwicklung und die daraus resultierende Einschätzung zukünftiger Chancen für Kohlenwasserstoff-Technologien.
Modelling of a hollow fibre bioartificial liver and pancreas.
Creators: name: Paris, Marc.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Engineering, Biomedical.

description: In the last two decades, significant advances in the development of bioartificial organs have been achieved. In particular the hollow fibre bioreactor has demonstrated enormous potential as a possible bioartificial organ. Although considerable study has been conducted, the field of process modelling, particularly in the case of the bioartificial liver, has generally been neglected. A one-dimensional model was therefore developed to predict the performance of the hollow fibre bioartificial pancreas and liver. The impact of bovine serum albumin polarisation in the fibre's extra capillary space on device performance was evaluated. The simulations conducted for the bioartificial pancreas showed that protein polarisation can significantly reduce device performance when the system relies on convective mass transport across the membrane. In the case of the bioartificial liver, protein polarisation resulted in an apparent reduction of ammonia and n-caproic acid consumption. Most of the performance increase observed for a system where no protein was present is due to species accumulation in the extra capillary space. The convective flux of ammonia and n-caproic acid across the membrane particularly improved device performance during start-up conditions.
Two-photon interference from silicon-vacancy centers in remote nanodiamonds
Creators: name: Waltrich, Richard
name: Klotz, Marco
name: Agafonov, Viatcheslav N.
name: Kubanek, Alexander
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Silicon-vacancy center
subject: DDC 530 / Physics
subject: Nanodiamonds
subject: Quantum optics
subject: Quantenoptik

description: The generation of indistinguishable photons is a key requirement for solid-state quantum emitters as a viable source for applications in quantum technologies. Restricting the dimensions of the solid-state host to a size well below the wavelength of light emitted by a defect-center enables efficient external optical coupling, for example, for hybrid integration into photonic devices. However, stringent restrictions on the host dimensions result in severe limitations on the spectral properties reducing the indistinguishability of emitted photons. Here, we demonstrate two-photon interference from two negatively charged silicon-vacancy centers located in remote nanodiamonds. The Hong–Ou–Mandel interference efficiency reaches 61 % with a coalescence time window of 0.35 ns. We furthermore show a high yield of pairs of silicon-vacancy centers with indistinguishable optical transitions. Therefore, our work opens new paths in hybrid quantum technology based on indistinguishable single-photon emitters in nanodiamonds.
Fforto tellen alle the circumstaunces: The royal entries of Henry VI (1431--32) and their manuscripts
Creators: name: Bourassa, Kristin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: History, European.

description: In 1429, the seven-year-old Henry VI was crowned king of England. He was crowned king of France in Paris in December 1431, a few days after his tenth birthday. Part procession, part spectacle, the civic-organized royal entries accompanying these events began with the greeting of the king by the city's officials outside the gates. The king was then led through the city, stopping to view pageants---often described by contemporaries as "mysteries"---along the procession route. The only king to be crowned in England and France, Henry VI was also the only ruler to make royal entries as king into both London and Paris. This study examines both entries, considering the events themselves as well as the documents describing them. It asks, what was the function of the event of the fifteenth-century royal entry in Paris and London, as well as of the documents describing these events? It considers royal entries on both sides of the Channel from the perspectives of both history and literature, combining an examination of these entries and their manuscripts for the first time. These descriptions were produced by fifteenth-century writers for a fifteenth-century audience, and were as much a part of the royal entry as was the procession through the city. This study argues that civic officials used both the format of the royal entry itself and the written descriptions of entries to promote their city's interests. Both London and Paris royal entry organizers used the event as a form of negotiation with the visiting king, an opportunity to express the city's expectations to the ruler. Although the themes and routes of successive entries could appear similar, the speeches and signs explaining individual pageants expressed very different sentiments. In London, civic officials used the documents describing entries to elevate their city, creating pro-London descriptions that were circulated in London-centric manuscripts. They deliberately used royal entry descriptions to promote their city.
Interoception in insula subregions as a possible state marker for depression - an exploratory fMRI study investigating healthy, depressed and remitted participants
Creators: name: Wiebking, Christine
name: Greck, Moritzde
name: Duncan, Niall W.
name: Tempelmann, Claus
name: Bajbou, Malek
name: Northoff, Georg
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background: Interoceptive awareness (iA), the awareness of stimuli originating inside the body, plays an important role in human emotions and psychopathology. The insula is particularly involved in neural processes underlying iA. However, iA-related neural activity in the insula during the acute state of major depressive disorder (MDD) and in remission from depression has not been explored. Methods: A well-established fMRI paradigm for studying (iA; heartbeat counting) and exteroceptive awareness (eA; tone counting) was used. Study participants formed three independent groups: patients suffering from MDD, patients in remission from MDD or healthy controls. Task-induced neural activity in three functional subdivisions of the insula was compared between these groups. Results: Depressed participants showed neural hypo-responses during iA in anterior insula regions, as compared to both healthy and remitted participants. The right dorsal anterior insula showed the strongest response to iA across all participant groups. In depressed participants there was no differentiation between different stimuli types in this region (i.e., between iA, eA and noTask). Healthy and remitted participants in contrast showed clear activity differences. Conclusions: This is the first study comparing iA and eA-related activity in the insula in depressed participants to that in healthy and remitted individuals. The preliminary results suggest that these groups differ in there being hypo- responses across insula regions in the depressed participants, whilst non- psychiatric participants and patients in remission from MDD show the same neural activity during iA in insula subregions implying a possible state marker for MDD. The lack of activity differences between different stimulus types in the depressed group may account for their symptoms of altered external and internal focus.
Role of the right anterior insula for the emergence of flow—a combined task-based fMRI activation and connectivity study
Creators: name: Ulrich, Martin
name: Niemann, Filip
name: Grön, Georg
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: flow experience
subject: salience
subject: anterior insula
subject: putamen
subject: functional connectivity
subject: functional magnetic resonance imaging
subject: intrinsic motivation
subject: DDC 610 / Medicine & health

description: The emergence of flow is a situation of high salience because externally oriented attention on the task and access to resources for goal-directed behavior are enhanced, while internally oriented or self-related cognition is decreased. The right anterior insula has been reported as a causal out-flow hub of the salience resting-state network, orchestrating the engagement of the central executive network (CEN) and the disengagement of the default-mode network (DMN) during a functional challenge. In the present study, we employed a combined task-based activation and connectivity analysis to investigate the role of the right anterior insula during the emergence of flow. A sample of 41 healthy male subjects was confronted with a functional challenge that permitted the emergence of flow during BOLD-based functional magnetic resonance imaging. Comparing connectivity changes in the right anterior insula during the flow condition against connectivity changes associated with control conditions of boredom and overload, relatively increased couplings were observed with the left and right dorsolateral prefrontal cortex. Activation data for these regions did, however, not show the flow-typical inverted U-shaped (invU) response pattern. Relatively decreased functional couplings encompassed ventral aspects of the striatum, but neither the amygdala nor the medial prefrontal cortex (MPFC). For the ventral striatum, activation data were consistent with the flow-typical U-shaped activation pattern, which supports the notion that under the high salience of autotelic situations, the anterior insula is much less positively coupled with the ventral striatum than under boundary conditions of boredom and overload. Taken together, present functional connectivity results were in alignment with the assumed role of the right anterior insula under conditions of different salience. However, this particular region does not appear to mediate the most typical flow-associated activation patterns.
A pilot study of the bedside tests for aspiration in acute stroke.
Creators: name: Biem, Henry Jay.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Health Sciences, Medicine and Surgery.

description: The aim of this thesis was to provide feasibility and statistical information that could be used to develop a grant proposal for a multidisciplinary study of the reliability and accuracy of the bedside diagnosis of aspiration and dysphagia in acute stroke patients. The objectives of this pilot study were: (1) To determine the feasibility of doing simple bedside tests for dysphagia and aspiration and determining intra-observer and inter-observer reliability. (2) To determine the required sample sizes to measure the inter-observer reliability of each of the video-recorded bedside tests with the Kappa statistic within a desired confidence interval based on estimates of the observed and expected agreements. (3) To determine the rate of admission of acute stroke patients at one hospital center and the approximate proportion of acute stroke patients who are eligible for enrollment and give consent. (4) To determine the approximate proportion of recruited acute stroke patients with the clinical outcomes of pneumonia and disruption of oral feeding. The pilot study used a prospective design to determine the agreement between two blinded observers for each of the various bedside tests recorded on videotape. It was conducted at Etobicoke General, a suburban community hospital. (Abstract shortened by UMI.)
title: Papel de la biopsia percutánea axilar en pacientes candidatos a biopsia selectiva de ganglio centinela.
Creators: name: García Ortega, María José
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Breast
subject: Interventional non-vascular
subject: Mammography
subject: Ultrasound
subject: Biopsy
subject: Neoplasia

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
La biopsia percutánea de ganglios axilares permite el diagnóstico de metástasis axilares,
orientando el manejo y tratamiento de la paciente diagnosticada de cáncer de mama,
sobre todo en pacientes candidatos a Biopsia selectiva del ganglio...
Anpassung an den Klimawandel als neues Politikfeld
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2017

description: In Deutschland ist - wie in vielen Mitgliedstaaten der EU - Anpassung an den Klimawandel als eigenes Politikfeld mit einer nationalen Strategie, einem Maßnahmenplan sowie für die Umsetzung zuständigen Akteuren etabliert. Insbesondere bei physischen, raumwirksamen Maßnahmen kommt dabei der kommunalen und regionalen Ebene eine maßgebliche Rolle zu. Auf EU-Ebene kann die Umsetzung insbesondere durch einen geeigneten Förder- und Rechtsrahmen unterstützt werden. Im Mittelpunkt des Kapitels stehen Klimaanpassungsstrategien auf den unterschiedlichen politischen Ebenen - von der EU bis zur Kommune -, Ansätze erfolgreicher Umsetzung und entsprechende Hemmnisse. Quelle: http://link.springer.com
title: Utilidad de la difusión para la localización tumoral en Resonancia Magnética rectal en el estadiaje local del carcinoma de recto
Creators: name: Ramos Rodriguez, Jose Ramon
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Colon
subject: Oncology
subject: Pelvis
subject: MR-Diffusion/Perfusion
subject: MR-Functional imaging
subject: MR
subject: Imaging sequences
subject: Molecular imaging
subject: Technical aspects
subject: Neoplasia

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Estudiar la efectividad de la secuencia de Difusión de agua en Resonancia Magnética (RM) en la localización anatómica del carcinoma de recto-sigma para realizar posterior estadiaje local y evitarse así procedimientos que pueden ser molestos...
Galaxy And Mass Assembly (GAMA): The wavelength dependence of galaxy structure versus redshift and luminosity
Creators: name: Kennedy, Rebecca
name: Bamford, Steven P.
name: Baldry, Ivan
name: Häußler, Boris
name: Holwerda, Benne W.
name: Hopkins, Andrew M.
name: Kelvin, Lee S.
name: Lange, Rebecca
name: Moffett, Amanda J.
name: Popescu, Cristina C.
name: Taylor, Edward
name: Tuffs, Richard J.
name: Vika, Marina
name: Vulcani, Benedetta
Publisher: name: Swinburne
Year: 2024

description: We study how the sizes and radial profiles of galaxies vary with wavelength, by fitting Sérsic functions simultaneously to imaging in nine optical and near-infrared bands. To quantify the wavelength dependence of effective radius we use the ratio, R, of measurements in two restframe bands. The dependence of Sérsic index on wavelength,N, is computed correspondingly. Vulcani et al. have demonstrated that different galaxy populations present sharply contrasting behaviour in terms ofRandN. Here we study the luminosity dependence of this result.We find that at higher luminosities, early-type galaxies display a more substantial decrease in effective radius withwavelength, whereas late types present a more pronounced increase in Sérsic index. The structural contrast between types thus increases with luminosity. By considering samples at different redshifts, we demonstrate that lower data quality reduces the apparent difference between the main galaxy populations. However, our conclusions remain robust to this effect. We show that accounting for different redshift and luminosity selections partly reconciles the size variation measured by Vulcani et al. with the weaker trends found by other recent studies. Dividing galaxies by visual morphology confirms the behaviour inferred using morphological proxies, although the sample size is greatly reduced. Finally, we demonstrate that varying dust opacity and disc inclination can account for features of the joint distribution of R and N for late-type galaxies. However, dust does not appear to explain the highest values of R and N. The bulge-disc nature of galaxies must also contribute to the wavelength dependence of their structure.