cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Wilks's Theorem, Global Fits, and Neutrino Oscillations
Creators: name: Hardin, J. M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Tests of models for new physics appearing in neutrino experiments often involve global fits to a quantum mechanical effect called neutrino oscillations. This paper introduces students to methods commonly used in these global fits starting from an understanding of more conventional fitting methods using log-likelihood and $χ^2$ minimization. Specifically, we discuss how the $Δχ^2$, which compares the $χ^2$ of the fit with the new physics to the $χ^2$ of the Standard Model prediction, is often interpreted using Wilks's theorem. This paper uses toy models to explore the properties of $Δχ^2$ as a test statistic for oscillating functions. The statistics of such models are shown to deviate from Wilks's theorem. Tests for new physics also often examine data subsets for "tension" called the "parameter goodness of fit". In this paper, we explain this approach and use toy models to examine the validity of the probabilities from this test also. Although we have chosen a specific scenario -- neutrino oscillations -- to illustrate important points, students should keep in mind that these points are widely applicable when fitting multiple data sets to complex functions.
description: Updates addressing reviewer comments
Women's transition back to work after maternity leave: the impact of maternal, infant, social and workplace factors
Creators: name: Gilbert, Melissa
Publisher: name: La Trobe
Year: 2024

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Psychological Science, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora.

Thesis with publications.
title: The Centennial Variation of El Niño Impact on Atlantic Tropical Cyclones
Creators: name: Yang, Ruixin
name: Fairley, Allison S.
name: Park, Wonsun
Publisher: name: Earth Interactions
Year: 2018
Subjects: subject: Tropical cyclones
subject: Atmosphere−ocean interaction
subject: Climate variability

description: Predicting tropical cyclone (TC) activity becomes more important every year while the understanding of what factors impact them continues to be complicated. El Niño–Southern Oscillation (ENSO) is one of the primary factors impacting the activities in both the Pacific and the Atlantic, but an extensive examination of the fluctuation in this system has yet to be studied in its entirety. This article analyzes the ENSO impacts on the Atlantic tropical cyclone activity during the assessed warm and cold years to show the dominant centennial-scale variation impact. This study looks to plausibly link this variation to the Southern Ocean centennial variability, which is rarely mentioned in any factors affecting the Atlantic tropical cyclone activity. This centennial variability could be used to enhance future work related to predicting tropical cyclones.
A Comprehensive Survey on Spectrum Sharing Techniques for 5G/B5G Intelligent Wireless Networks: Opportunities, Challenges and Future Research Directions
Creators: name: Patil, Anita
name: Iyer, Sridhar
name: Lopez, Onel L. A.
name: Pandya, Rahul J
name: Pai, Krishna
name: Kalla, Anshuman
name: Kallimani, Rakhee
Publisher: name: arXiv
Year: 2022
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: The increasing popularity of Internet of Everything and small-cell devices has enormously accelerated traffic loads. Consequently, increased bandwidth and high data rate requirements stimulate the operation at the millimeter wave and the Tera-Hertz spectrum bands in the fifth generation (5G) and beyond 5G (B5G) wireless networks. Furthermore, efficient spectrum allocation, maximizing the spectrum utilization, achieving efficient spectrum sharing (SS), and managing the spectrum to enhance the system performance remain challenging. To this end, recent studies have implemented artificial intelligence and machine learning techniques, enabling intelligent and efficient spectrum leveraging. However, despite many recent research advances focused on maximizing utilization of the spectrum bands, achieving efficient sharing, allocation, and management of the enormous available spectrum remains challenging. Therefore, the current article acquaints a comprehensive survey on intelligent SS methodologies for 5G and B5G wireless networks, considering the applications of artificial intelligence for efficient SS. Specifically, a thorough overview of SS methodologies is conferred, following which the various spectrum utilization opportunities arising from the existing SS methodologies in intelligent wireless networks are discussed. Subsequently, to highlight critical limitations of the existing methodologies, recent literature on existing SS methodologies is reviewed in detail, classifying them based on the implemented technology, i.e., cognitive radio, machine learning, blockchain, and multiple other techniques. Moreover, the related SS techniques are reviewed to highlight significant challenges in the B5G intelligent wireless network. Finally, to provide an insight into the prospective research avenues, the article is concluded by presenting several potential research directions and proposed solutions.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Wo Shuey Ming, Young Yet Shang, Yuen Chong Kut, Low Soon, Seto Yee, Choy Wing Jsao, Wong Wah, Wong Shew Lin, Wong Wing Chun, Mrs. Chow Shee, Wong Shew Ying, Wong Shew King, Wong Wing Yim, Huie Wing, Wuie Gin Tong
Kingdom come
Creators: name: Copenhaver, G.P.
name: Qu, L.-J.
name: Köhler, C.
name: Barsh, G.S.
Publisher: name: Public Library of Science
Year: 2020

description: The tumultuous events of 2020 have prompted many of us to reflect upon the forces that divide us, like pandemics and politics, as well as the commonalities that unite us, like our shared hope for a better future. Scientists often face a similar problem—when to lump or split the things they study. PLOS Genetics has decided that while plants (Fig 1) obey the same fundamental genetic principles as other organisms, their unique qualities, many of which are critically important to human health and welfare, merit special attention in the same way as our other sections: Cancer Genetics, Epigenetics, Evolution, Methods, Natural Variation, and Prokaryotic Genetics. To support this goal, we are creating a new Plant Genetics section for the journal that will be led by the inaugural Senior Editors Claudia Koehler and Li-Jia Qu.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Seto Sam, Chee Chong Fum, Chee Chang, Leong Wo Jung, Leong Ming Luk, Tsang Gin, Ng York, Wong Yow, Pon Lee Him, Kwan Wah.
DeepTetrad: high-throughput image analysis of meiotic tetrads by deep learning in Arabidopsis thaliana
Creators: name: Kim, J.
name: Choi, K.
name: Byun, D.
name: Kim, J.
name: Henderson, I.R.
name: Kim, E.-J.
name: Lim, E.-C.
name: Park, Y.M.
name: Cho, H.S.
name: Park, J.
name: Hwang, I.
name: Copenhaver, G.P.
Publisher: name: Blackwell Publishing Ltd
Year: 2020

description: Meiotic crossovers facilitate chromosome segregation and create new combinations of alleles in gametes. Crossover frequency varies along chromosomes and crossover interference limits the coincidence of closely spaced crossovers. Crossovers can be measured by observing the inheritance of linked transgenes expressing different colors of fluorescent protein in Arabidopsis pollen tetrads. Here we establish DeepTetrad, a deep learning-based image recognition package for pollen tetrad analysis that enables high-throughput measurements of crossover frequency and interference in individual plants. DeepTetrad will accelerate the genetic dissection of mechanisms that control meiotic recombination.
Progress towards the two-thirds conjecture on locating-total dominating sets
Creators: name: Chakraborty, Dipayan
name: Foucaud, Florent
name: Hakanen, Anni
name: Henning, Michael A.
name: Wagler, Annegret K.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Combinatorics (math.CO)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We study upper bounds on the size of optimum locating-total dominating sets in graphs. A set $S$ of vertices of a graph $G$ is a locating-total dominating set if every vertex of $G$ has a neighbor in $S$, and if any two vertices outside $S$ have distinct neighborhoods within $S$. The smallest size of such a set is denoted by $γ^L_t(G)$. It has been conjectured that $γ^L_t(G)\leq\frac{2n}{3}$ holds for every twin-free graph $G$ of order $n$ without isolated vertices. We prove that the conjecture holds for cobipartite graphs, split graphs, block graphs and subcubic graphs.
Giant gate-tunable renormalization of spin-correlated flat-band states and bandgap in a 2D magnetic insulator
Creators: name: Lyu, Pin
name: Sødequist, Joachim
name: Sheng, Xiaoyu
name: Qiu, Zhizhan
name: Tadich, Anton
name: Li, Qile
name: Edmonds, Mark T.
name: Redondo, Jesús
name: Švec, Martin
name: Olsen, Thomas
name: Lu, Jiong
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Emergent quantum phenomena in two-dimensional van der Waal (vdW) magnets are largely governed by the interplay between the exchange and Coulomb interactions. The ability to tune the Coulomb interaction in such strongly correlated materials enables the precise control of spin-correlated flat-band states, bandgap (Eg) and unconventional magnetism, all of which are crucial for next-generation spintronics and magnonics applications. Here, we demonstrate a giant gate-tunable renormalization of spin-correlated flat-band states and bandgap in magnetic chromium tribromide (CrBr3) monolayers grown on graphene. Our gate-dependent scanning tunneling spectroscopy (STS) studies reveal that the inter-flat-band spacing and bandgap of CrBr3 can be continuously tuned by 120 meV and 240 meV respectively via electrostatic injection of carriers into the hybrid CrBr3/graphene system, equivalent to the modulation of the Cr on-site Coulomb repulsion energy by 500 meV. This can be attributed to the self-screening of CrBr3 arising from the gate-induced carriers injected into CrBr3, which dominates over the opposite trend from the remote screening of the graphene substrate. Precise tuning of the spin-correlated flat-band states and bandgap in 2D magnets via electrostatic modulation of Coulomb interactions not only provides new strategies for optimizing the spin transport channels but also may exert a crucial influence on the exchange energy and spin-wave gap, which could raise the critical temperature for magnetic order.
description: 21 pages, 4 figures
Women's transition back to work after maternity leave: the impact of maternal, infant, social and workplace factors
Creators: name: Coulson, Melissa
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Psychological Science, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora.

Thesis with publications.
Detecting the heterodyning of gravitational waves
Creators: name: Stegmann, Jakob
name: Vermeulen, Sander M.
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Gravitational waves modulate the apparent frequencies of other periodic signals. Low-frequency gravitational waves could therefore be detected by observing frequency modulations in signals from higher-frequency sources, e.g., those from binary white dwarfs detected with the LISA gravitational-wave detector. We propose a concrete method to extract these modulations by coherently adding the cross-spectra of a large number of well-resolved quasi-monochromatic signals. We apply this method to the case of LISA, and find this method would enable the detection of background gravitational wave strain amplitudes of, e.g., $A\simeq10^{-10}$ at a frequency $F\simeq10^{-8}\,\rm Hz$, given current projections for the number and properties of Galactic binary white dwarfs and the sensitivity of the instrument. We also estimate (to within an order of magnitude) that this method could potentially compete with that of current Pulsar Timing Arrays when using signals from binary neutron stars such as those expected to be observed with proposed detectors like DECIGO. Our results show that gravitational-wave detectors could be sensitive at frequencies outside of their designed bandwidth using the same infrastructure, which has the potential to open up unexplored and otherwise inaccessible parts of the gravitational wave spectrum.
description: 12 pages, 6 figures, 1 table
title: Feasibility study of 4D-online monitoring of density gradients induced by lung cancer treatment using carbon ions
Creators: name: Reidel, Claire-Anne
name: Pierobon, Enrico
name: Horst, Felix
name: Gesson, Lévana
name: Paz, Athena
name: Graeff, Christian
name: Steinsberger, Timo
name: Zink, Klemens
name: Witt, Matthias
name: Senger, Yannick
name: Finck, Christian
name: Vanstalle, Marie
name: La Tessa, Chiara
name: Durante, Marco
name: Weber, Uli
name: Schuy, Christoph
Publisher: name: Frontiers Media S.A.
Year: 2025

description: Tumor motion is a major challenge for scanned ion-beam therapy. In the case of lung tumors, strong under- and overdosage can be induced due to the high density gradients between the tumor- and bone tissues compared to lung tissues. This work proposes a non-invasive concept for 4D monitoring of high density gradients in carbon ion beam therapy, by detecting charged fragments. The method implements CMOS particle trackers that are used to reconstruct the fragment vertices, which define the emission points of nuclear interactions between the primary carbon ions and the patient tissues. A 3D treatment plan was optimized to deliver 2 Gy to a static spherical target volume. The goodness of the method was assessed by comparing reconstructed vertices measured in two static cases to the ones in a non-compensated moving case with an amplitude of 20 mm. The measurements, performed at the Marburg Ion-Beam Therapy Center (MIT), showed promising results to assess the conformity of the delivered dose. In particular to measure overshoots induced by high density gradients due to motion with 83.0 ± 1.5% and 92.0 ± 1.5% reliability based on the ground truth provided by the time-resolved motor position and depending on the considered volume and the iso-energy layers.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Chan Yow Hen, Yin Hoy, Jung Wei Yuey, Jung Hong Wah, [Jung Jan Chik], Jung Kan Yin, Shum Poy King, Shum Won, Shum Kan, Shum Luan.
Conservation and divergence in the meiocyte srnaomes of arabidopsis, soybean, and cucumber
Creators: name: Huang, N.
name: Copenhaver, G.P.
name: Wang, Y.
name: Fang, X.
name: Huang, J.
name: Wang, C.
name: Wang, Y.
name: Ma, H.
name: Li, X.
Publisher: name: American Society of Plant Biologists
Year: 2020

description: Meiosis is a critical process for sexual reproduction. During meiosis, genetic information on homologous chromosomes is shuffled through meiotic recombination to produce gametes with novel allelic combinations. Meiosis and recombination are orchestrated by several mechanisms including regulation by small RNAs (sRNAs). Our previous work in Arabidopsis (Arabidopsis thaliana) meiocytes showed that meiocyte-specific sRNAs (ms-sRNAs) have distinct characteristics, including positive association with the coding region of genes that are transcriptionally upregulated during meiosis. Here, we characterized the ms-sRNAs in two important crops, soybean (Glycine max) and cucumber (Cucumis sativus). Ms-sRNAs in soybean have the same features as those in Arabidopsis, suggesting that they may play a conserved role in eudicots. We also investigated the profiles of microRNAs (miRNAs) and phased secondary small interfering RNAs in the meiocytes of all three species. Two conserved miRNAs, miR390 and miR167, are highly abundant in the meiocytes of all three species. In addition, we identified three novel cucumber miRNAs. Intriguingly, our data show that the previously identified phased secondary small interfering RNA pathway involving soybean-specific miR4392 is more abundant in meiocytes. These results showcase the conservation and divergence of ms-sRNAs in flowering plants, and broaden our understanding of sRNA function in crop species.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Choy Jun, Yip Shing, Fong Jai, Ko Tong, Leong Man, [Leong Gin Jone], [Lim Lin], Lim Hong, [Lin Doo Yin], Lin Yow.
The Arabidopsis anaphase-promoting complex/cyclosome subunit 8 is required for male meiosis
Creators: name: Wang, Y.
name: Xu, J.
name: Ma, H.
name: Copenhaver, G.P.
name: Xu, R.-Y.
name: Zheng, B.
name: Niu, B.
name: Wang, L.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Faithful chromosome segregation is required for both mitotic and meiotic cell divisions and is regulated by multiple mechanisms including the anaphase-promoting complex/cyclosome (APC/C), which is the largest known E3 ubiquitin-ligase complex and has been implicated in regulating chromosome segregation in both mitosis and meiosis in animals. However, the role of the APC/C during plant meiosis remains largely unknown. Here, we show that Arabidopsis APC8 is required for male meiosis. We used a combination of genetic analyses, cytology and immunolocalisation to define the function of AtAPC8 in male meiosis. Meiocytes from apc8-1 plants exhibit several meiotic defects including improper alignment of bivalents at metaphase I, unequal chromosome segregation during anaphase II, and subsequent formation of polyads. Immunolocalisation using an antitubulin antibody showed that APC8 is required for normal spindle morphology. We also observed mitotic defects in apc8-1, including abnormal sister chromatid segregation and microtubule morphology. Our results demonstrate that Arabidopsis APC/C is required for meiotic chromosome segregation and that APC/C-mediated regulation of meiotic chromosome segregation is a conserved mechanism among eukaryotes.
TOF MLEM Adaptation for the Total-Body J-PET with a Realistic Analytical System Response Matrix
Creators: name: Shopa, R. Y.
name: Baran, J.
name: Klimaszewski, K.
name: Krzemień, W.
name: Raczyński, L.
name: Wiślicki, W.
name: Brzeziński, K.
name: Chug, N.
name: Coussat, A.
name: Curceanu, C.
name: Czerwiński, E.
name: Dadgar, M.
name: Dulski, K.
name: Gajewski, J.
name: Gajos, A.
name: Hiesmayr, B. C.
name: Valsan, E. Kavya
name: Korcyl, G.
name: Kozik, T.
name: Kumar, D.
name: Kapłon, Ł.
name: Moskal, G.
name: Niedźwiecki, S.
name: Panek, D.
name: Parzych, S.
name: del Rio, E. Pérez
name: Ruciński, A.
name: Sharma, S.
name: Shivani
name: Silarski, M.
name: Skurzok, M.
name: Stȩpień, E.
name: Ardebili, F. Tayefi
name: Ardebili, K. Tayefi
name: Moskal, P.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Medical Physics (physics.med-ph)
subject: Computational Physics (physics.comp-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We report a study of the original image reconstruction algorithm based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM), developed for the total-body (TB) Jagiellonian PET (J-PET) scanners. The method is applicable to generic cylindrical or modular multi-layer layouts and is extendable to multi-photon imaging. The system response matrix (SRM) is represented as a set of analytical functions, uniquely defined for each pair of plastic scintillator strips used for the detection. A realistic resolution model (RM) in detector space is derived from fitting the Monte Carlo simulated emissions and detections of annihilation photons on oblique transverse planes. Additional kernels embedded in SRM account for TOF, parallax effect and axial smearing. The algorithm was tested on datasets, simulated in GATE for the NEMA IEC and static XCAT phantoms inside a 24-module 2-layer TB J-PET. Compared to the reference TOF MLEM with none or a shift-invariant RM, an improvement was observed, as evaluated by the analysis of image quality, difference images and ground truth metrics. We also reconstructed the data with additive contributions, pre-filtered geometrically and with non-TOF scatter correction applied. Despite some deterioration, the obtained results still capitalise on the realistic RM with better edge preservation and superior ground truth metrics. The envisioned prospects of the TOF MLEM with analytical SRM include its application in multi-photon imaging and further upgrade to account for the non-collinearity, positron range and other factors.
Evaluating the strength of genetic results: Risks and responsibilities
Creators: name: Barsh, G.S.
name: Cooper, G.M.
name: Copenhaver, G.P.
name: Tang, H.
name: Williams, S.M.
name: Sirugo, G.
Publisher: name: Public Library of Science
Year: 2019

description: In this issue, we are publishing an Editorial Expression of Concern in connection with a recent article on the genetics of multiple sclerosis (MS). In brief, the authors used exome sequencing of families with multiple individuals diagnosed with MS to identify 21 missense or nonsense mutations in 12 genes, and they then suggest that these 12 genes provide a platform for additional research. Following publication, concerns were raised about the validity of some of the statements made in the manuscript, leading us to a series of discussions, both internally and with the authors. The purpose of this editorial is to describe the sequence of events, the rationale for our eventual publication of the Editorial Expression of Concern, and, in doing so, comment and engender discussion more broadly on the role of scientists as editors in what can sometimes be a grey area: the causal relationship between genetic and phenotypic variation.
Additional file 1 of Complexities of implementing Maternal and Perinatal Death Surveillance and Response in crisis-affected contexts: a comparative case study
Creators: name: Mary, Meighan
name: Tappis, Hannah
name: Scudder, Elaine
name: Creanga, Andreea A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Additional file 1. Implementation outcomes summarized by case. Key study implementation outcomes are summarized by case.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Yee Yick Jone, Wong Park Jun, Lee Loy Him, Lim Hing, Wong Nom Sai, Chan Fung Lee Mon Yow, Dang On, Jang Why, Won Wing.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Wong Jang Shew, Wong Sair Fon, Sam Wo, [Chow Kwang Yisk], Yee Bing Jing, Mah Fon Yat, Mah Chong Poy, Mah Wing Chook, Kwan Song Gin, Kwan Song Him.
Additional file 1 of Effect of noninvasive ventilation on mortality and clinical outcomes among patients with severe hypoxemic COVID-19 pneumonia after high-flow nasal oxygen failure: a multicenter retrospective French cohort with propensity score analysis
Creators: name: Goury, Antoine
name: Houlla, Zeyneb
name: Jozwiak, Mathieu
name: Urbina, Tomas
name: Turpin, Matthieu
name: Lavalard, Alexandra
name: Laghlam, Driss
name: Voicu, Sebastian
name: Rosman, Jeremy
name: Coutureau, Claire
name: Mourvillier, Bruno
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Virology

description: Supplementary Material 1
Meiotic DNA repair in the nucleolus employs a nonhomologous end-joining mechanism
Creators: name: Sims, J.
name: Schlögelhofer, P.
name: Copenhaver, G.P.
Publisher: name: American Society of Plant Biologists
Year: 2019

description: Ribosomal RNA genes are arranged in large arrays with hundreds of rDNA units in tandem. These highly repetitive DNA elements pose a risk to genome stability since they can undergo nonallelic exchanges. During meiosis, DNA double-strand breaks (DSBs) are induced as part of the regular program to generate gametes. Meiotic DSBs initiate homologous recombination (HR), which subsequently ensures genetic exchange and chromosome disjunction. In Arabidopsis (Arabidopsis thaliana), we demonstrate that all 45S rDNA arrays become transcriptionally active and are recruited into the nucleolus early in meiosis. This shields the rDNA from acquiring canonical meiotic chromatin modifications and meiotic cohesin and allows only very limited meiosis-specific DSB formation. DNA lesions within the rDNA arrays are repaired in an RAD51-independent but LIG4-dependent manner, establishing that nonhomologous end-joining maintains rDNA integrity during meiosis. Utilizing ectopically integrated rDNA repeats, we validate our findings and demonstrate that the rDNA constitutes an HR-refractory genome environment.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Wong Gong, Chong Gim Yet, [Mary Won Long], [?], [May Won Gong], Chow June, Mrs. Lew Shee, Mr. Lee Foo, Mrs. Lee Foo, Mr. Henry Lee, Mrs. Henry Lee, Lai Fong, Mr. Poon Ging, Mrs. Poon Ging, [Mr. Wong Shuk Yin], [M
Modelling the Accelerating Universe with $f(Q)$ Gravity: Observational Consistency
Creators: name: Narawade, S. A.
name: Shekh, S. H.
name: Mishra, B.
name: Khyllep, Wompherdeiki
name: Dutta, Jibitesh
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we present a cosmological model within the framework of symmetric teleparallel gravity, focusing on $f(Q)$ gravity, where $Q$ represents the non-metricity scalar. Utilizing cosmological datasets, we derive an accelerating cosmological model by constraining its free parameters. To achieve this, we determine the parametric form of the Hubble parameter using a well-motivated $f(Q)$ function. Remarkably, all obtained values fall within the range suggested by cosmological observations. By employing the best-fit parameters, we calculate the present geometrical parameters and demonstrate the accelerating behaviour of the Universe. Furthermore, we thoroughly examine the evolutionary behaviours of the Universe, noting that our model converges to the $Λ$CDM model at late times. Finally, we investigate the energy conditions and find a violation of the strong energy condition, which could provide a valuable understanding of the nature of dark energy.
description: 15 pages, 10 figures
The largest subunit of DNA polymerase delta is required for normal formation of meiotic type I Crossovers
Creators: name: Zhang, J.
name: Huang, J.
name: Copenhaver, G.P.
name: Wang, Y.
name: Han, Y.
name: Ma, H.
name: Wang, H.
name: Wang, C.
Publisher: name: American Society of Plant Biologists
Year: 2019

description: Meiotic recombination contributes to the maintenance of the association between homologous chromosomes (homologs) and ensures the accurate segregation of homologs during anaphase I, thus facilitating the redistribution of alleles among progeny. Meiotic recombination is initiated by the programmed formation of DNA double strand breaks, the repair of which requires DNA synthesis, but the role of DNA synthesis proteins during meiosis is largely unknown. Here, we hypothesized that the lagging strand-specific DNA Polymerase d (POL d) might be required for meiotic recombination, based on a previous analysis of DNA Replication Factor1 that suggested a role for lagging strand synthesis in meiotic recombination. In Arabidopsis (Arabidopsis thaliana), complete mutation of the catalytic subunit of POL d, encoded by AtPOLD1, leads to embryo lethality. Therefore, we used a meiocyte-specific knockdown strategy to test this hypothesis. Reduced expression of AtPOLD1 in meiocytes caused decreased fertility and meiotic defects, including incomplete synapsis, the formation of multivalents, chromosome fragmentation, and improper segregation. Analysis of meiotic crossover (CO) frequencies showed that AtPOLD1 RNAi plants had significantly fewer interference-sensitive COs than the wild type, indicating that AtPOL σ participates in type I CO formation. AtPOLD1RNAi atpol2a double mutant meiocytes displayed more severe meiotic phenotypes than those of either single mutant, suggesting that the function of AtPOLD1 and AtPOL2A is not identical in meiotic recombination. Given that POL σ is highly conserved among eukaryotes, we hypothesize that the described role of POL σ here in meiotic recombination likely exists widely in eukaryotes.
Towards An Eu Strategy For International Cultural Relations: An Initial, Critical But Constructive Analysis
Creators: name: Higgott, Richard
name: Van Langenhove, Luk
Publisher: name: Zenodo
Year: 2016
Subjects: Cultural Diplomacy
EU Strategy

description: This policy paper offers an early assessment of the joint communication "Towards an EU Strategy of international cultural relations" delivered by High Representative Federica Mogherini last June. This communication was issued two weeks before the UK voted to leave the EU and just shy of three weeks before the HR also delivered "A Global Strategy for the European Union's Foreign and Security Policy". Timing of the strategy paper on international cultural relations was thus, to say the least, less than propitious. The other two events do and will cast massive shadows over it.
Doubling down on forensic twin studies
Creators: name: Rothstein, M.
name: Williams, S.M.
name: Weir, B.
name: Copenhaver, G.P.
name: Tang, H.
name: Barsh, G.S.
Publisher: name: Public Library of Science
Year: 2018

description: Twins have amazed and beguiled the human imagination throughout human history. In Genesis, Jacob uses his status as a twin to deceive his aged father Isaac and steal his bother Esau’s birthright—an event that sets the stage for the rest of the Old Testament. In Shakespeare’s The Comedy of Errors, not one, but two, sets of twins (Dromio and Antipholus × 2) are the core of the bard’s tale.
title: A Transcranial Magnetic Stimulation Investigation of the Role of the Temporal Parietal Junction in Social Influence and Risky Decision Making
Creators: name: Kirby, Zena M
Publisher: name: George Mason University
Year: 2017
Subjects: subject: TMS
subject: TPJ
subject: Decision-making
subject: Social influence
subject: Risk
subject: Mentalizing

description: The process by which individuals make decisions has important implications in a number of fields, such as economics and psychology. Several factors influence choice including characteristics of the decision itself, as well as environmental and individual factors. One source of deviation from typical decision-making is social influence, especially in decisions involving risk. The current study investigated the role of the rTPJ on social influence and risky decision-making using inhibitory cTBS. We hypothesized that susceptibility to social influence on risk-taking in an economic decision-making task would decrease following stimulation to the rTPJ, while risk-taking in the absence of social information should be unaffected. However, our results did not illustrate a significant relationship between stimulation and susceptibility to social influence, such that social influence increased risk-taking behavior. This may indicate that while the rTPJ is involved in decision-making in a social context, other brain regions are responsible for the incorporation of social information into economic risk-taking. However, it is likely that computations of risk were inhibited through suppression of the nearby posterior parietal cortex. This is corroborated by trending effects of increased risk-taking and slower reaction times on the decision-making task, and the absence of deficits on a theory of mind task.
Additional file 1 of Rare correlation of somatic PRKACA mutations with pregnancy-associated aldosterone- and cortisol-producing adenomas: a case report and literature review
Creators: name: Lin, Jianfan
name: Li, Yufei
name: Huang, Zhenxing
name: Zhu, Yingli
name: Li, Li
name: Yang, Haiyan
name: Liang, Xinghuan
name: Qin, Yingfen
name: Zhou, Jia
name: Xian, Jing
name: Liu, Deyun
name: Lu, Decheng
name: Luo, Zuojie
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Supplementary Material 1
Arabidopsis thaliana FANCD2 promotes meiotic crossover formation
Creators: name: Copenhaver, G.P.
name: Oliver, C.
name: Mosiolek, M.
name: Kerzendorfer, C.
name: Janisiw, M.P.
name: Schweizer, D.
name: Ladurner, R.
name: Sims, J.
name: Kurzbauer, M.-T.
name: Schlögelhofer, P.
name: Pradillo, M.
Publisher: name: American Society of Plant Biologists
Year: 2018

description: Fanconi anemia (FA) is a human autosomal recessive disorder characterized by chromosomal instability, developmental pathologies, predisposition to cancer, and reduced fertility. So far, 19 genes have been implicated in FA, most of them involved in DNA repair. Some are conserved across higher eukaryotes, including plants. The Arabidopsis thaliana genome encodes a homolog of the Fanconi anemia D2 gene (FANCD2) whose function in DNA repair is not yet fully understood. Here, we provide evidence that AtFANCD2 is required for meiotic homologous recombination. Meiosis is a specialized cell division that ensures reduction of genomic content by half and DNA exchange between homologous chromosomes via crossovers (COs) prior to gamete formation. In plants, a mutation in AtFANCD2 results in a 14% reduction of CO numbers. Genetic analysis demonstrated that AtFANCD2 acts in parallel to both MUTS HOMOLOG4 (AtMSH4), known for its role in promoting interfering COs and MMS AND UV SENSITIVE81 (AtMUS81), known for its role in the formation of noninterfering COs. AtFANCD2 promotes noninterfering COs in a MUS81-independent manner and is therefore part of an uncharted meiotic CO-promoting mechanism, in addition to those described previously.
Coloring and Recognizing Directed Interval Graphs
Creators: name: Gutowski, Grzegorz
name: Junosza-Szaniawski, Konstanty
name: Klesen, Felix
name: Rzążewski, Paweł
name: Wolff, Alexander
name: Zink, Johannes
Publisher: name: arXiv
Year: 2023
Subjects: subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences

description: A \emph{mixed interval graph} is an interval graph that has, for every pair of intersecting intervals, either an arc (directed arbitrarily) or an (undirected) edge. We are particularly interested in scenarios where edges and arcs are defined by the geometry of intervals. In a proper coloring of a mixed interval graph $G$, an interval $u$ receives a lower (different) color than an interval $v$ if $G$ contains arc $(u,v)$ (edge $\{u,v\}$). Coloring of mixed graphs has applications, for example, in scheduling with precedence constraints; see a survey by Sotskov [Mathematics, 2020]. For coloring general mixed interval graphs, we present a $\min \{ω(G), λ(G)+1 \}$-approximation algorithm, where $ω(G)$ is the size of a largest clique and $λ(G)$ is the length of a longest directed path in $G$. For the subclass of \emph{bidirectional interval graphs} (introduced recently for an application in graph drawing), we show that optimal coloring is NP-hard. This was known for general mixed interval graphs. We introduce a new natural class of mixed interval graphs, which we call \emph{containment interval graphs}. In such a graph, there is an arc $(u,v)$ if interval $u$ contains interval $v$, and there is an edge $\{u,v\}$ if $u$ and $v$ overlap. We show that these graphs can be recognized in polynomial time, that coloring them with the minimum number of colors is NP-hard, and that there is a 2-approximation algorithm for coloring.
description: To appear in Proc. ISAAC 2023
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Tom Hoo, Chew Bow Chun, [Lee Yuen], [Lee Sang], Lim Hew, Lim Dew, Gin Ying Gee, [Wong Quong], Lew Yin Ben, Chung Quon.
New insights into the role of DNA synthesis in meiotic recombination
Creators: name: Wang, Y.
name: Copenhaver, G.P.
name: Ma, H.
name: Huang, J.
Publisher: name: Science in China Press
Year: 2016

description: Meiosis comprises two rounds of nuclear division following a single phase of DNA replication, leading to the production of haploid gametes and is essential for sexual reproduction in eukaryotes. Unlike mitosis, meiosis involves homologous chromosome pairing, synapsis, and recombination during prophase I. Meiotic recombination not only ensures the accurate segregation of homologs, but also redistributes alleles among offspring. DNA synthesis is a critical process during meiotic recombination, but our understanding of the proteins that execute and regulate it is limited. This review summarizes the recent advances in defining the role of DNA synthesis in meiotic recombination through analyses of DNA synthesis genes, with specific emphasis on DNA polymerases (e.g., Polε and Polδ), replication processivity factor RFC1 and translesion polymerases (e.g., Polζ). We also present a new double strand break repair model for meiotic recombination, which includes lagging strand DNA synthesis and leading strand elongation. Finally, we propose that DNA synthesis is one of critical factors for discriminating meiotic recombination pathways and that this differentiation may be conserved among eukaryotes.
title: The American National Theatre and Academy [brochure]
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 1995
Subjects: subject: ANTA, Board of Directors
subject: ANTA, Executive Committee
subject: ANTA, Staff
subject: ANTA, Volunteers
subject: ANTA, Corporate Members
subject: ANTA, Guest Artists
subject: ANTA, Technical Advice
subject: ANTA, Personnel Service
subject: ANTA, Script Service
subject: ANTA, Speakers Bureau
subject: ANTA, Theatre Promotion
subject: ANTA, Experimental Theatre
subject: ANTA, Playhouse
subject: ANTA, Play Series 1950-1951
subject: ANTA, Fund Campaign
subject: ANTA, National Theatre Assembly
subject: ANTA, International Theatre
subject: ANTA, on TV
subject: ANTA, on Radio
subject: ANTA, on Records
subject: ANTA, Album
subject: ANTA
subject: Hayes, Helen
subject: Stewart, Fred
subject: Mielziner, Jo
subject: McCandless, Stanley
subject: Harrison, Wallace

description: Brochure.
Bringing PLOS Genetics Editors to Preprint Servers
Creators: name: Barsh, G.S.
name: Copenhaver, G.P.
name: Singh, N.D.
name: Bergman, C.M.
name: Brown, C.D.
Publisher: name: Public Library of Science
Year: 2016

description: What's the first thing you do after making a cool new discovery? If you're like us, you run up and down the hallway, propelled by excitement, eager to show your latest result to your colleagues. But the hallway is a pretty limited audience, so we soon turn to publishing our work in a peer-reviewed journal to show it to the whole world (assuming it is an open-access journal). That's when the fun of discovery can come to a screeching halt and turn into dreary hours of formatting and online form submission only to wait weeks, if not months, for your manuscript to wend its way through the peer-review system. Preprint servers (PPS) can short-circuit those cheerless steps, at least for a time, and allow the fruits of your labor to be seen immediately by all who are interested. In addition to increasing the visibility of authors' work, PPS provide opportunities for journals to identify manuscripts that are good fit for their audience. In that vein, PLOS Genetics is pleased to announce a new initiative to use PPS for identifying and soliciting manuscripts, as part of PLOS' overall mission to improve the efficiency and accessibility of science communication (and, of course, to make the process less cheerless for authors). As part of that effort, we now have a dedicated team of editors who will focus on identifying manuscripts on PPS that are potentially suitable for publication in PLOS Genetics.
BOSHLANGʻICH SINF OʻQUVCHILARINING KREATIV IMKONIYATLARI VA ULARNING NAMOYON BOʻLISHI
Creators: name: Tulegenova Dilfuza Ergash qizi.  Toshkent Kimyo xalqaro universiteti magistranti   Tel: +99899 955 79 32   E-mail: dilfuza77@mail.ru
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqolada boshlangʻich sinf oʻquvchilarining kreativ (ijodiy) salohiyati, uning shakllanish jarayoni va namoyon boʻlish holatlari tahlil qilingan. Mualliflar bolalarning yosh psixologiyasi va individual xususiyatlarini hisobga olgan holda, ijodiy fikrlash, fantaziya, mustaqil gʻoyalar bildirish qobiliyatini rivojlantirish usullarini yoritib berishgan. Maqolada kreativ imkoniyatlarning namoyon boʻlishiga taʼsir etuvchi omillar, jumladan taʼlim muhiti, oʻqituvchi yondashuvi, faol oʻqitish metodlari va ota-ona roli haqida soʻz boradi. Ilmiy tadqiqot natijalariga tayanib, bolalarda kreativlikni ragʻbatlantirish boʻyicha aniq tavsiyalar ham keltirilgan. Ushbu ish pedagoglar va psixologlar uchun foydali manba boʻlishi mumkin.
title: The Coach-Athlete Relationship: A CrossFit Perspective
Creators: name: Flores, David
Publisher: name: George Mason University
Year: 2013
Subjects: subject: CrossFit
subject: Satisfaction
subject: Relationship quality
subject: Relationship duration
subject: Direct and meta-perspectives
subject: Gender

description: The purpose of this study was to examine how CrossFit athletes and coaches perceived the quality of the coach-athlete relationship based on the 3+1Cs model (Jowett, 2007). 110 participants (93 athletes, 17 coaches) reported on their direct and meta-perceptions of relationship quality by taking Jowett and Clark-Carter’s (2006) version of the Coach-Athlete Relationship Questionnaire (CART-Q), and direct and meta-perceptions of satisfaction with training/instruction, performance, and personal treatment, by taking a modified version of Reimer and Chelladurai’s (1998) Athlete Satisfaction Questionnaire (ASQ). Results showed that athletes and coaches did not differ on their perceptions of relationship quality and the three satisfaction variables. Neither gender nor relationship duration had a significant effect on athletes and coaches’ perceptions. Athletes’ meta-perceptions of the three Cs significantly predicted their perceptions of all three satisfaction variables. Implications and future research directions are discussed.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Yip Shong Yuen, [Mah Wing Dart], Lee Luon Gin, Lee Fai, Gin Sing Jam, Hong Sai Luon, Yip Non Jhang, Leong Nay, Leong Lok, Jang Hing King.
Improving Automated Hemorrhage Detection in Sparse-view Computed Tomography via Deep Convolutional Neural Network based Artifact Reduction
Creators: name: Thalhammer, Johannes
name: Schultheiss, Manuel
name: Dorosti, Tina
name: Lasser, Tobias
name: Pfeiffer, Franz
name: Pfeiffer, Daniela
name: Schaff, Florian
Publisher: name: arXiv
Year: 2023
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Medical Physics (physics.med-ph)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: This is a preprint. The latest version has been published here: https://pubs.rsna.org/doi/10.1148/ryai.230275
 Purpose: Sparse-view computed tomography (CT) is an effective way to reduce dose by lowering the total number of views acquired, albeit at the expense of image quality, which, in turn, can impact the ability to detect diseases. We explore deep learning-based artifact reduction in sparse-view cranial CT scans and its impact on automated hemorrhage detection. Methods: We trained a U-Net for artefact reduction on simulated sparse-view cranial CT scans from 3000 patients obtained from a public dataset and reconstructed with varying levels of sub-sampling. Additionally, we trained a convolutional neural network on fully sampled CT data from 17,545 patients for automated hemorrhage detection. We evaluated the classification performance using the area under the receiver operator characteristic curves (AUC-ROCs) with corresponding 95% confidence intervals (CIs) and the DeLong test, along with confusion matrices. The performance of the U-Net was compared to an analytical approach based on total variation (TV). Results: The U-Net performed superior compared to unprocessed and TV-processed images with respect to image quality and automated hemorrhage diagnosis. With U-Net post-processing, the number of views can be reduced from 4096 (AUC-ROC: 0.974; 95% CI: 0.972-0.976) views to 512 views (0.973; 0.971-0.975) with minimal decrease in hemorrhage detection (P<.001) and to 256 views (0.967; 0.964-0.969) with a slight performance decrease (P<.001). Conclusion: The results suggest that U-Net based artifact reduction substantially enhances automated hemorrhage detection in sparse-view cranial CTs. Our findings highlight that appropriate post-processing is crucial for optimal image quality and diagnostic accuracy while minimizing radiation dose.
description: 11 pages, 6 figures, 1 table
title: 8.2024,2: Themenheft "Blended Learning"
Creators: name: Hauer, Beatrix
name: Kasberger, Gudrun
name: Keplinger, Gudrun
name: Kramer, Martin
name: Schöftner, Thomas
Publisher: name: Private Pädagogische Hochschule der Diözese Linz
Year: 2024

description: Pädagogische Horizonte; 8.2024,2
SIZING OF A MICROGRID MODEL FOR NALUAMA RURAL COMMUNITY IN ZAMBIA USING MICROGRIDSPY AND RAMP
Creators: name: Mwaya, Clifford Kapungwe
name: Kyessi, Michael
name: Tarimo, Kelvin
Publisher: name: Zenodo
Year: 2025

description: This report constitutes the outcome of a three-weeks capacity building activity on GEP-OnSSET as part of the 2025 Energy Modelling Platform for Africa workshop. The author(s) collected input data, set parameters, calibrated the model, and ran electrification investment scenarios for Zambia in order to explore pathways leading to the achievement of electrification targets. The results of this analysis are not conclusive, but rather the output of experimentation with the model and thus only indicative. You may contact the author for more information and/or questions about the methodology, limitations, and follow-up activities of this study.