cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
DESIGN for COASTALSCAPE. The spatial dimension of land-sea planning
Creators: name: INNOCENTI, ALBERTO
Publisher: name: Universit� IUAV di Venezia
Year: 2020

description: The PhD examines the phenomenon of coastal territories and their land and sea dynamics by a planning perspective. The study starts from the consideration that half of the world?s population interacts daily with the sea through living in coastal cities and that these geographical areas are under constant pressure from anthropic activities and climate change threats.
This doctoral dissertation aims to understand how a well-structured framework of knowledge about land-sea interactions might enhance the resilience of coastalscapes. The research considers multiple approaches to tackle the topic from diverse points of view. The PhD path is divided into two key milestones.
The first key milestone of the research, coming along on a double literature review on land-sea interactions, attempts to detect, find gaps and build a framework of knowledge on land-sea interactions in order to make more accessible the topic to scientists and policymakers.
The second key milestone endeavours to enlarge the knowledge gained from the first key milestone; by looking at the coastal area through a different lens, it tries to interpret the land-sea interactions phenomena that shape the coastalscape. This milestone is based on multiple case studies approach through a mapping analysis. The first phase is focused on understanding the typologies of anthropic and natural environments present in the case studies through three types of mapping analysis. The second phase zooms in on edge to understand the components of the coastalscape by revealing a common mapping language.
The approach and methods used in the research - the double literature review, fluxes schemes and mapping - have contributed to the knowledge and even though applied on four specific cases can be relevant as guidance through the study of other cases.
Il progetto della citt� medievale. Indagine sulla crescita di San Gimignano.
Creators: name: MARINO, MARCO
Publisher: name: Universit� IUAV di Venezia
Year: 2021

description: Questo � un libro disegnato pi� che un libro scritto perch� � un un libro di morfologia urbana. � un libro che analizza una meraviglia del Bel Paese, la piccola citt� di San Gimignano in Toscana, e come questo gioiello urbano sia stato inventato, costruito e cresciuto.
sj-docx-1-qjp-10.1177_17470218211044694 – Supplemental material for Does omitting the accent mark in a word affect sentence reading? Evidence from Spanish
Creators: name: Marcet, Ana
name: Perea, Manuel
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-qjp-10.1177_17470218211044694 for Does omitting the accent mark in a word affect sentence reading? Evidence from Spanish by Ana Marcet and Manuel Perea in Quarterly Journal of Experimental Psychology
sj-pdf-2-cep-10.1177_03331024211042390 - Supplemental material for The characteristics of COVID-19 vaccine-related headache: Clues gathered from the healthcare personnel in the pandemic
Creators: name: Ekizoglu, Esme
name: Gezegen, Haşim
name: Yalınay Dikmen, Pınar
name: Orhan, Elif Kocasoy
name: Ertaş, Mustafa
name: Baykan, Betül
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, sj-pdf-2-cep-10.1177_03331024211042390 for The characteristics of COVID-19 vaccine-related headache: Clues gathered from the healthcare personnel in the pandemic by Esme Ekizoglu, Haşim Gezegen, Pınar Yalınay Dikmen, Elif Kocasoy Orhan, Mustafa Ertaş and Betül Baykan in Cephalalgia
title: Endurance of quantum coherence due to particle indistinguishability in noisy quantum networks
Creators: name: Perez-Leija, Armando
name: Guzmán-Silva, Diego
name: León-Montiel, Roberto de J.
name: Gräfe, Markus
name: Heinrich, Matthias
name: Moya-Cessa, Hector
name: Busch, Kurt
name: Szameit, Alexander
Publisher: name: Nature Publishing Group
Year: 2025

description: Quantum coherence, the physical property underlying fundamental phenomena such as multi-particle interference and entanglement, has emerged as a valuable resource upon which modern technologies are founded. In general, the most prominent adversary of quantum coherence is noise arising from the interaction of the associated dynamical system with its environment. Under certain conditions, however, the existence of noise may drive quantum and classical systems to endure intriguing nontrivial effects. In this vein, here we demonstrate, both theoretically and experimentally, that when two indistinguishable non-interacting particles co-propagate through quantum networks affected by non-dissipative noise, the system always evolves into a steady state in which coherences accounting for particle indistinguishabilty perpetually prevail. Furthermore, we show that the same steady state with surviving quantum coherences is reached even when the initial state exhibits classical correlations.
Additional file 2 of A Case Study from the Overexpression of OsTZF5, Encoding a CCCH Tandem Zinc Finger Protein, in Rice Plants Across Nineteen Yield Trials
Creators: name: Grondin, Alexandre
name: Natividad, Mignon A.
name: Ogata, Takuya
name: Jan, Asad
name: Gaudin, Amélie C. M.
name: Trijatmiko, Kurniawan R.
name: Liwanag, Evelyn
name: Maruyama, Kyonoshin
name: Fujita, Yasunari
name: Yamaguchi-Shinozaki, Kazuko
name: Nakashima, Kazuo
name: Slamet-Loedin, Inez H.
name: Henry, Amelia
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Additional file 2: Supplemental tables and figures.
sj-pdf-2-imr-10.1177_03000605211044045 - Supplemental material for Cerebral infarction caused by systemic sclerosis: a case report
Creators: name: Wang, Qingqing
name: Zhang, Mengen
name: Zhai, Mingfeng
name: Li, Zongyou
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Dentistry not elsewhere classified
subject: Emergency Medicine
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Nursing not elsewhere classified
subject: Nutrition and Dietetics not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Orthopaedics
subject: Sports Medicine
subject: Otorhinolaryngology
subject: Aged Health Care
subject: Paediatrics
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Public Health and Health Services not elsewhere classified
subject: Respiratory Diseases
subject: Sociological Methodology and Research Methods
subject: Surgery

description: Supplemental material, sj-pdf-2-imr-10.1177_03000605211044045 for Cerebral infarction caused by systemic sclerosis: a case report by Qingqing Wang, Mengen Zhang, Mingfeng Zhai and Zongyou Li in Journal of International Medical Research
title: Structural and Functional Characterisation of a Novel TAXI TRAP Binding Protein from Bordetella pertussis
Creators: name: Jaques, Lily Mae
Publisher: name: University of Kent
Year: 2025

description: Tripartite ATP-independent periplasmic (TRAP) transporters are secondary active transporters found within prokaryotes that are dependent on a substrate binding protein (SBP) and two uneven transmembrane components for the translocation of substrates across the membrane. The presence of an SBP allows for increased affinity and specificity of substrates thus resulting in a highly efficient transporter that is able to gather nutrients in the most depleted and competitive of environments. The TAXI (TRAP associated immunogenic) subclass of TRAP transporters has been neglected from literature, however their SBPs have been shown to follow the same architecture as the better characterised DctP-type TRAPs. This consists of a 300-350 amino acid monomeric bilobular protein composed of 2 α/β globular regions connected via a flexible hinge.
Within this study, we highlight the discovery of a TAXI TRAP SBP from Bordetella Pertussis with an unusual residue length and architecture. This SBP is 503 residues in length and is composed of an α/β globular N-terminal domain, an interdomain helical region and a domain resembling a TRAP SBP. Through (1) size exclusion chromatography (2) computational modelling and (3) the introduction of site-specific cysteine mutations we uncover this TAXI TRAP SBP to be a stable dimer with the dimerisation point being within the interdomain helical region. Following this, differential scanning fluorimetry and intrinsic tyrosine fluorescence reveal this SBP to bind to L-glutamate with high affinity. We also uncover five other potential glutamate binding dimeric TAXI SBPs, highlighting a possible novel family of dimeric SBP- dependent secondary active transporters.
Shedding light on DNA-protein interactions involved in the nucleotide excision repair pathway
Creators: name: Fritzen, Remi
Publisher: name: University of St Andrews
Year: 2021
Subjects: subject: XPA
subject: RPA
subject: TFIIH
subject: XPD
subject: Nucleotide excision repair
subject: Single-strand binding proteins
subject: XPC
subject: Single molecule microscopy
subject: QH467.F8
subject: DNA repair

description: DNA, or deoxyribonucleic acid, contains the molecular blueprint of organisms. Although, very stable, DNA can be damaged by genotoxic agents such as UV-light, reactive oxygen species or chemotherapeutic drugs, amongs others. Organisms have evolved several biological pathways to repair different types of damage and nucleotide excision repair (NER) is one of them. NER repairs mainly lesions inducing structural distortion of the double helix. Briefly, the lesion is detected, unwinding takes place to create a 30 nucleotides long bubble, the damage-containing single strand is then excised; using the opposite strand as a template, the DNA is resynthesized and ligated. Nucleotide Excision Repair is a non-mutagenic repair system. Single-strand DNA binding proteins (SSB) are involved in NER and many other pathways. Their role is to coat and protect the ssDNA from degradation and re-hybridisation. Here, we studied SSBs from Saccharolobus solfataricus and Sulfolobus acidocaldarius as well as a chimeric protein containing DNA binding domains from both organisms. We showed that the chimeric protein had better resistance to extreme conditions of temperature, ionic strength or acidic pH. We also proved that our chimeric SSB can be used as a tool to image single strand DNA or RNA using super resolution microscopy. The first step of NER is damage recognition by XPC. We studied XPC binding to a DNA substrate and showed the possibility of two XPC binding to a damage whilst demonstrating that the presence of a nick on the DNA backbone does not constitute a substrate for XPC. Furthermore, we used single molecule FRET technique to show that XPC could bind a three nucleotides bubble in two different modes, showing a strong preference for one of these binding modes. The second step is the unwinding by the XPD helicase, we studied the impact of the purine/pyrimidine composition on the unwinding activity and investigated a possible damage sensor role of XPD, using Archaean models. To complete our work, we demonstrated a cooperative effect on the distortion of the repair bubble of XPA and RPA.
sj-pdf-1-jcb-10.1177_0271678X211045222 - Supplemental material for Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome
Creators: name: Nogueira, Ricardo C
name: Aries, Marcel
name: Minhas, Jatinder S
name: H Petersen, Nils
name: Xiong, Li
name: Kainerstorfer, Jana M
name: Castro, Pedro
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 110306 Endocrinology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 110320 Radiology and Organ Imaging
subject: Cell Biology
subject: Biochemistry
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jcb-10.1177_0271678X211045222 for Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome by Ricardo C Nogueira, Marcel Aries, Jatinder S Minhas, Nils H Petersen, Li Xiong, Jana M Kainerstorfer and Pedro Castro in Journal of Cerebral Blood Flow & Metabolism
Additional file 1 of A mobile app to challenge obsessional beliefs in adolescents: a protocol of a two-armed, parallel randomized controlled trial
Creators: name: Saman, Yuliya
name: Pascual-Vera, Belén
name: Corberán, Marta
name: Arnáez, Sandra
name: Roncero, María
name: García-Soriano, Gemma
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1.
Intermetallic Growth of Cu6Sn5 as a function of Cu crystallographic orientation
Creators: name: Huang, Ziyun
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Materials engineering not elsewhere classified

description: The morphologies and growth behavior of Cu6Sn5 intermetallic compound (IMC) formed between Sn-based solder and large-grain polycrystalline Cu substrate were systematically investigated. Hexagonal Cu6Sn5 grains were observed to form at certain reflow condition, which matches well with the literature results for IMC growing on single crystal substrate. The kinetics of IMC growth was also investigated and different mechanisms were proposed for different evolution stages. It was observed that facet formation should be a growth shape rather than an equilibrium shape, and the orientation relationship between Cu and Cu6Sn5 was studied using scanning electron microscope (SEM) and Electron backscatter diffraction (EBSD), and were visualized on inverse pole figure.
title: In vitro immunological techniques in fascioliasis
title: A study of in vitro immunological techniques in fascioliasis
titleType: AlternativeTitle
Creators: name: Newitt, Andrew Buchanan
Publisher: name: The University of Edinburgh
Year: 1975
Subjects: subject: Annexe MSc Digitisation Project 2022 Block 36
subject: Enzyme linked Immunosorbent Assay
subject: Fasciola hepatica
subject: enzyme-linked immunosorbent assay (ELISA
subject: radioimmunoassay
subject: somatic fluke antigen
subject: RIA

description: Experiments were conducted to examine ways of monitoring immunological responses in sheep to infection with Fasciola hepatica. The enzyme- linked immunosorbent assay (ELISA), the radioimmunoassay, and the agar gel precipitin technique were evaluated using the same somatic fluke antigen, for sensitivity and accuracy in the serodiagnosis of fascioliasis whilst an in vitro method for culturing lymphocytes of infected and uninfected rabbits and sheep was used to detect an immunological transformational response to the somatic fluke antigen. Comparison was made with haematological changes observed in vivo during the course of an experimental infection. Although ELISA using a tube technique, failed to demonstrate a significant difference between serum from uninfected and infected sheep, a microtitre technique appeared to give satisfactory results. The RIA appeared to provide a highly reproducable and sensitive method for monitoring the antibody response in fascioliasis. Close agreement was obtained between the agar gel precipitin technique using a somatic fluke antigen and RIA. Despite highly variable data and lack of adequate controls, evidence for immunological mediated transformation by sheep lymphocytes was obtained from in vitro cultures made during the prepatent period of a fluke infection. This was correlated to cellular changes seen in vivo. Conversely, there appeared to be an impairment of the cellular response in chronically infected sheep. Thus based on previous authors findings with this technique, evidence suggested that cell mediated immunity existed in fascioliasis. Results obtained using rabbit and sheep lymphocytes showed differences in the cultural kinetics of the different species and indicated the need for further study into the cultural behaviour and requirements of sheep lymphocytes.
Legitimation Code Theory as an Analytical Tool for Examining Discourse Within Integrated STEM Education
Creators: name: Dankenbring, Chelsey A
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Other education not elsewhere classified

description: To prepare students for the complex, multidisciplinary problems they will face outside of the classroom, current reform initiatives advocate for the integration of content and practices from science, technology, engineering, and mathematics (STEM) in the science classroom. One approach, integrated STEM, uses the engineering design process as a vehicle for learning. However, these lessons can be challenging for students, so it is essential that science educators employ various teaching practices to scaffold student learning. One way to achieve this is through the use of written and oral discourse that promotes meaning-making. The studies in this dissertation utilize Legitimation Code Theory as an analytical framework to create semantic profiles of an integrated STEM unit and middle school teachers’ implementation of integrated STEM lessons. Specifically, we analyze the semantic gravity, or the extent to which meaning is rooted within the context it is acquired in, to map and identify semantic patterns that may promote or constrain meaning-making. The results of these studies indicate that Legitimation Code Theory can be a useful tool for developing and examining integrated STEM curricular materials, evaluating teacher discourse during the implementation of integrated STEM lessons, ascertaining how teachers are integrating multiple disciplinary discourses, and identifying areas where teachers may benefit from additional support as they learn to implement integrated STEM. Keywords: integrated STEM, legitimation code theory, discourse.
title: Epidemiological changes in nematode parasite populations of sheep at Easter Bush Farm, Midlothian
Creators: name: Woodham, Clive Bernard
Publisher: name: The University of Edinburgh
Year: 1975
Subjects: subject: Annexe MSc Digitisation Project 2022 Block 36

description: Three flocks of Suffolk ewes and. one of Cheviot ewes and their lambs at Easter Bush Farm, Midlothian were monitored using routine helminthological tests between October 1974 and August 1975* Ostertagia circumcincta was found to be the predominant species in the Suffolks but not in the Cheviots. A major contribution to egg output was also made by Cooperia curticei and Trichostrongylus axei.* The abbreviation P.P.R. is used throughout this thesis although it is not the desire of the author to discriminate between a post parturient rise and a periparturient rise when it is used in the text. A post-parturient rise of strongyle eggs was observed in Suffolk ewes lambing in January whilst a periparturient rise occurred in both the Suffolk and Cheviot ewes lambing in April. Eggs of Ostertagia species were predominant throughout the rise in all ewes except the Cheviots. The pattern of the P.P.R.* of the Suffolk ewes, lambing in January, but housed until Mid-April, was significantly prolonged as compared with a similar group at pasture. Climatic and husbandry factors influencing the establishment of parasitic nematodes in lambs born in January and in April were studied to assess population and generic differences between the groups of lambs. Two peaks of strongyle egg counts were observed in January born Suffolk lambs reared on pasture, the first probably resulting from overwintered Ostertagia spp and Ifematodirus spp larvae and the second, which was common to all lambs, occurred in late July as a result of infective larvae derived from the P.P.R. Eggs of Strongyloides papillosus were found in 2 to 8 week old lambs. Some of this infection had been transmitted via the ewe's milk. The identification of nematode species found in the gastrointestinal tract of sheep by the measurement of egg dimensions and the observation of development when incubated for 7 days at 4.5°0 was a useful diagnostic tool to study generic variation in the eggs excreted by the sheep. The faeces of the two Cheviot ewes, which were studied using the technique, contained very few Ostertagia spp eggs, in contrast to those from the April lambing Suffolk ewes running with them. The difference may be the result of a genetic variation in the susceptibility of the Cheviot ewes to ostertagiasis, but because of the small sample examined it was impossible to make a statistical analysis of the significance of this observation. * The abbreviation P.P.R. is used throughout this thesis although it is not the desire of the author to discriminate between a post parturient rise and a periparturient rise when it is used in the text.
Additional file 1 of NOMe-HiC: joint profiling of genetic variant, DNA methylation, chromatin accessibility, and 3D genome in the same DNA molecule
Creators: name: Fu, Hailu
name: Zheng, Haizi
name: Chen, Xiaoting
name: Weirauch, Matthew T.
name: Muglia, Louis J.
name: Wang, Li
name: Liu, Yaping
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Supplementary Methods. Figure S1. NOMe-HiC generates high-quality multi-omics data at different cell types. Figure S2. GpC methyltransferase footprint level is correlated with PolII binding signals. Figure S3. Average GCH methyltransferase footprint and HCG methylation level around distal (a). CTCF (b). FOS (c). MAFK (d). MAZ (e). MIX1 binding sites in IMR-90. Figure S4. GCH (left) and WCG (right) methylation level measured by locus-specific amplification at (a). LAMB3, (b) CTCF peak (c).SNRPN site of NOMe-HiC libraries from IMR-90 and GM12878 cell lines. Figure S5. NOMe-HiC reveals similar sets of differential expressed genes as total RNA-seq. Figure S6. Example plot of NOMe-HiC. Figure S7. Nuclei status at each step of NOMe-HiC library preparation. Figure S8. NOMe-HiC generated highly reproducible multi-omics data across biological replicates at two cell lines. Figure S9. NOMe-HiC generated reproducible long-range GCH accessibility concordance across biological replicates at two cell lines. Figure S10. NOMe-HiC reproduced the long-range methylation concordance at two cell lines. Figure S11. The boxplot of the number of WCG, HCG, and GCH at loop anchors in NOMe-HiC. Figure S12. NOMe-HiC reveals the long-range allele-specific GCH methyltransferase footprint. Figure S13. The enrichment of allele-specific TF binding sites at the SNP anchors of allelespecific GCH methyltransferase footprint loci.
Il colore verde di Berlino Giorgio Grassi e l'idea di citt� rurale
Creators: name: FORMENTI, CARLOTTA
Publisher: name: Universit� IUAV di Venezia
Year: 2020

description: Berlino ha da sempre offerto lo scenario ideale per imbastire nuove e differenti riflessioni d?architettura.
Nel respiro di questa tesi, si presta a rappresentare un certo tipo di rapporto tra la citt� e il territorio che la circonda.
Fin dal XIX secolo, Berlino ha fatto del paesaggio un tema determinante all?interno del dibattito circa il proprio sviluppo urbano: questo si � svolto al principio attraverso la difesa del suolo pubblico e dello spazio aperto in un?epoca di massiccia speculazione edilizia, durante il Movimento Moderno ha portato all?elaborazione di una proporzione che legasse il costruito con le aree destinate a verde e, vista la storia particolare della capitale tedesca, nel secondo dopoguerra ha fornito ad architetti e urbanisti lo spunto per suggerire una diversa idea di citt�, immersa nel verde, secondo i principi dello Stadtlandschaft e della gegliederte und aufgelockerte Stadt (citt� articolata e diffusa).
L?attenzione a un progetto integrato tra natura e architettura diventa un carattere identitario di Berlino, mettendo in crisi la forzosa distinzione tra la sfera urbana e quella rurale, tra citt� e campagna.
Gli studi condotti sul tema hanno portato a evidenziare come i due termini si influenzino reciprocamente: come l?urbano sempre pi� invada il mondo rurale, ma anche come certi caratteri del rurale siano presenti storicamente all?interno della citt� e come questi determinino una vera e propria ?vocazione?, in senso collettivistico, dell?architettura della citt�.
In futuro si tender� sempre pi� ad una commistione tra l?urbano e il rurale, ma ancora rimane da stabilire secondo quali modalit� questo potrebbe verificarsi: la citt�-rurale � una delle alternative possibili.
Giorgio Grassi, nei suoi scritti come nelle sue opere, tanto nell?attivit� didattica come in quella professionale, ha dedicato ampio spazio allo studio della relazione tra citt� e campagna, facendone uno dei temi ricorrenti del proprio progetto d?architettura.
Il suo incontro con Berlino si � risolto nell?elaborazione di proposte che raccolte insieme sembrerebbero quasi suggerire un piano ? o un indirizzo ? per lo sviluppo della citt�; tuttavia � nel progetto di ricostruzione dell?area dell?ex Prinz-Albrecht Palais che si riconosce un esempio probante di come sia possibile declinare il carattere rurale all?interno della citt�, fornendo al tempo stesso la dimostrazione di come l?elemento naturale acquisti valore formale all?interno della composizione architettonica.
Additional file 1 of Network analysis of posttraumatic stress and posttraumatic growth symptoms among women in subsequent pregnancies following pregnancy loss
Creators: name: Shen, Qiaoqiao
name: Fu, Qi
name: Mao, Chen
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Mathematical Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: Supplementary Material 1
DESIGN, SYNTHESIS, AND PRECLINICAL EVALUATION OF LIGAND-TARGETED CONJUGATES FOR CANCER RADIOTHERANOSTICS
Creators: name: Lindeman, Spencer D
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Medicinal and biomolecular chemistry not elsewhere classified
Organic chemical synthesis
Biochemistry and cell biology not elsewhere classified
Molecular medicine
Radiation and matter

description: For any drug candidate to be approved by the U.S. Food and Drug Administration, it must meet strict standards for safety and efficacy. While the field of nuclear medicine is over 100 years old, traditional methods such as external beams or systematic administration have rarely met these standards or have limited application. Ligand-targeted therapy and diagnostics, or “theranostics,” has emerged in the past several decades as an exciting field that offers new possibilities to design drugs that are both safe and effective. When applied to nuclear medicine, the field of ligand-targeted radioactive theranostics is younger still, with many critical lessons being discovered and applied currently. This dissertation outlines the necessary principles of radioactive theranostic drug design, then demonstrates the application of several more recent techniques to improve both the efficacy and safety of radioactive theranostics targeting two high priority oncological targets: fibroblast activation protein alpha and folate receptor.
sj-pdf-1-aor-10.1177_00034894211045264 – Supplemental material for The efficacy of Tranexamic Acid Administration in Patients Undergoing Tonsillectomy: An Updated Meta-Analysis
Creators: name: Kuo, Cathleen C.
name: DeGiovanni, Jason C.
name: Carr, Michele M.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-aor-10.1177_00034894211045264 for The efficacy of Tranexamic Acid Administration in Patients Undergoing Tonsillectomy: An Updated Meta-Analysis by Cathleen C. Kuo, Jason C. DeGiovanni and Michele M. Carr in Annals of Otology, Rhinology & Laryngology
Stretchable 4-Channel Neck RF Coil for 3T MRI
Creators: name: Gim, Minseon
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Biomedical engineering not elsewhere classified

description: Advancements on flexible radiofrequency (RF) coils have been made to accommodate a variety of body sizes with great image quality and a comfortable imaging process. RF coils are magnetic field antennas for magnetic resonance imaging (MRI) that broadcast the RF signal to the patient and receive the returning signal to affect the image quality. The conventional neck RF coil is rigid and requires the patients to be in supine position. Due to its characteristics, the patients who have difficulties to move their neck experience an uncomfortable imaging process. The novel 4-channel neck RF coil is made of conductive silver thread embroidered on stretchable fabric to provide patients a more comfortable experience with lightweight and flexible materials. A wide range of neck sizes can be covered with the stretchable materials and great image quality can be acquired due to the RF coil positioned close to the source. The stretchable RF coil was built as non-overlapping 4 channels in zigzag stitch pattern and tested on a dielectric phantom, which was made to have the permittivity and conductivity of muscle at 128 MHz. The research can be extended to stretchable RF coils with more channels and different stitching patterns. It also has potential to be applied on joints such as wrist and ankle due to its flexibility to cover the curved surface.
Genera of Integer Representations and the Lyndon-Hochschild-Serre Spectral Sequence
Creators: name: Neuffer, Chris Karl
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Algebra and number theory
Category theory, k theory, homological algebra

description: There has been in the past ten to fifteen years a surge of activity concerning the cohomology of semi-direct product groups of the form $\mathbb{Z}^{n}\rtimes$G with G finite. A problem first stated by Adem-Ge-Pan-Petrosyan asks for suitable conditions for the Lyndon-Hochschild-Serre Spectral Sequence associated to this group extension to collapse at second page of the Lyndon-Hochschild-Serre spectral sequence. In this thesis we use facts from integer representation theory to reduce this problem to only considering representatives from each genus of representations, and establish techniques for constructing new examples in which the spectral sequence collapses.
Additional file 1 of Factorial validity and comparability of the six translations of the Rivermead Post-Concussion Symptoms Questionnaire translations: results from the CENTER-TBI study
Creators: name: Zeldovich, Marina
name: Bockhop, Fabian
name: Covic, Amra
name: Mueller, Isabelle
name: Polinder, Suzanne
name: Mikolic, Ana
name: van der Vlegel, Marjolein
name: von Steinbuechel, Nicole
Publisher: name: figshare
Year: 2024
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: Additional file 1. Supplementary tables.
Reuse Design Project: Strategie e strumenti per il riuso di elementi edilizi in architettura come preservazione delle risorse materiali
Creators: name: ZATTA, ELISA
Publisher: name: Universit� IUAV di Venezia
Year: 2021

description: La tesi di ricerca approfondisce il tema del riuso di prodotti e componenti edilizi quale strategia circolare e sostenibile per la gestione del costruito. Essa muove dalla duplice potenzialit� che tale processo presenta attraverso la conservazione delle risorse materiali, limitando gli impatti dettati dalla produzione di rifiuti da costruzione e demolizione, nonch� preservando, attraverso la conservazione formale e funzionale dell?elemento nella sua integrit�, la cultura materiale che lo ha prodotto.
Partendo dal quadro teorico e dello stato dell?arte, la tesi si struttura attraverso quattro linee di indagine parallele e complementari, mirate a restituire la
complessit� del tema secondo una visione quanto pi� possibile trasversale. La prima definisce il contributo dei processi di riuso a una sostenibilit� intesa non solo in ottica ambientale, ma anche sociale, culturale ed economica. La seconda esamina il valore conferito alla pratiche di reimpiego da parte dei progettisti contemporanei, evidenziando come essi vi individuino un significato culturale, al quale si associano ragioni di matrice ambientale, etico-sociale o di potenzialit� espressiva. La terza linea di indagine approfondisce le incongruenze e lacune della cornice normativa europea relativa al tema, individuando le ricadute di questo quadro sulle problematiche pregresse del settore. La quarta esamina la potenziale applicazione di questa strategia a scala urbana, definendo il Reuse Design Project quale ?processo progettuale che, a partire dalla formulazione del concept di un nuovo edificio fino alla sua costruzione, prevede, studia e compie l?integrazione nello stesso di prodotti e componenti edilizi, derivanti da altre costruzioni, che il progettista individua e ritiene adeguati al progetto?.
Gli esiti della ricerca consentono di determinare l?idoneit� del riuso di prodotti e componenti edilizi quale strumento sostenibile per la gestione del costruito
esistente, promuovendo la potenziale diffusione futura di tale approccio. Oltre a identificare suggerimenti e azioni da intraprendere in ambito normativo per
favorire il reimpiego, la tesi propone degli strumenti operativi volti a massimizzare l?efficiacia del Reuse Design Project. L?applicazione di tali strumenti, simulata su di un caso studio reale, consente non solo di esaminarne gli esiti in termini di processo progettuale, ma anche di confrontarli con quelli di uno scenario convenzionale sotto il profilo della fattibilit� tecnico-economica e degli impatti incorporati.
L?analisi dei risultati ottenuti evidenzia i caratteri innovativi propri dell?approccio progettuale volto al riuso di elementi edilizi, delle figure professionali coinvolte
e della gestione del processo di decostruzione, nonch� la formazione di tipo culturale necessaria per promuovere questa strategia nella pratica di architettura.
sj-docx-2-jpx-10.1177_23743735211039313 - Supplemental material for Experiences of Patients on Natural Herbal Treatments for Diabetes Mellitus at the Diabetes Clinic in Base Hospital - Matara, Sri Lanka
Creators: name: Edussuriya, A.S.J.
name: Subhashini, S.Y.S.
name: Amarasinghe, K.D.S.
name: Kumari, G.S.D.
name: Perera, K.M.O.N.
name: Munidasa, K.G.P.K.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Medicine

description: Supplemental material, sj-docx-2-jpx-10.1177_23743735211039313 for Experiences of Patients on Natural Herbal Treatments for Diabetes Mellitus at the Diabetes Clinic in Base Hospital - Matara, Sri Lanka by A.S.J. Edussuriya, S.Y.S. Subhashini, K.D.S. Amarasinghe, G.S.D. Kumari, K.M.O.N. Perera and K.G.P.K. Munidasa in Journal of Patient Experience
Mind, Body, Spirit: Muslim Women's Experiences in Therapy
Creators: name: Azmat, Alia
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Health counselling
Feminist theory
Curriculum and pedagogy theory and development
Counselling psychology
Health psychology
Mental health services
Health and community services

description: This dissertation presents in the form of two distinct chapters conceptually related in nature. The first chapter integrates literature from various fields such as indigenous, womanist, and feminist lenses to propose nine principles when working with Muslim women. The purpose of the second chapter is to examine Muslim women’s experiences in therapy at university counseling centers. The study explores women’s experiences from a social determinants of health perspective and a narrative inquiry method—namely, how intrapersonal, interpersonal, institutional, community, and policy factors inform women’s experiences. Qualitative analysis from interviews with six women suggests Muslim women navigate multiple systems which inform their beliefs about health and their experiences in therapy.
The impact of cold war on Somalia-USA relations in Somalia
Creators: name: Marian, Ali Hassan
Publisher: name: Zenodo
Year: 2025
Subjects: cold war
Somalia-USA relations
The impact of cold war on Somalia-USA relations in Somalia

description: ABSTRACT

The purpose of this study is To make assessment the impact of cold war on Somalia-USA relations. The overall aim of this study was guided by the very important objectives: To examine the monetary rewards on employee retention to the business in some selected businesses in Mogadishu Somalia. To define the impact of job enrichment on employee retention to the business in some selected businesses in Mogadishu, Somalia. To determine the influence of Training on employee retention to the business in some selected businesses in Mogadishu Somalia. The study was conducted from January 2024 to June 2024. This research was used descriptive design, through questionnaire design to describe the characteristics and correlation to measure central tendency of matters of the questionnaire. The total number of population in the study was employed 63 intellectual in the Mogadishu City as a case study since the time and cost could not allow accessing all the media sectors in the City of Mogadishu. 54 participants of sample size of different gender who have been selected from the population departments within the sectors of this scope in Mogadishu. These participants have been chosen according to the possibility of getting accurate and reliable information. The sampling procedure of this study was non-probability sampling especially purposive sampling to conduct the research, and also to consider the significance of research reality. This research study was collected primarily data using questionnaires. In this study quantitative data analysis was used. The analysis was carried out with the use of help Statistical Package for Social Sciences (SPSS version 20), that was measured the use of in Mogadishu, Benadir, Somalia. The major findings that supported the argument include the objectives and even the dependent variable of the study. For instance the questions of the first objective generally result a common concept of that motivation on employee retention to the business in some selected metropolis in Mogadishu, Somalia. The study also recommends to the social networks management providers to control their account users in order to promote the business secure and satisfaction and employee relations’ performance.
How design can contribute to children's neurological rehabilitation? Case study: Co-designing paediatric rehabilitation programs for learning disabilities
Creators: name: KOZLOVA, ANASTASIA
Publisher: name: Universit� IUAV di Venezia
Year: 2015

description: What is the role of designer in project development of rehabilitation programs? Designer plays the conductive role between different groups of specialists of various competences and frames of reference (e.g. engineers, software developers, doctors, therapists etc.), and communities of individuals with particular characteristics (potential users or customers: patients, children, parents etc.), uniting them together as a productive multidisciplinary team and contributing knowledge of his own competence (product design, graphic design, interface design, user experience design, ergonomics etc.) In order to be able to organize, manage and be the valuable part of the project developing team, designer should inevitably become a multidisciplinary researcher as well. Answering the main research questions: How design can contribute to children?s neurological rehabilitation? Present research exposed the example of successfully developing multidisciplinary project on robotic rehabilitation system for Dysgraphia. In our case the therapeutic equipment for certain neurological disorder in a certain infant neuropsychiatric department is being brought to a new quality level. Consequently patient?s therapeutic experience is to become more pleasant and exciting, so the efficiency of rehabilitation process is being improved. Moreover our suggestion is that using our general guidelines of project development in this field would bring to similar positive results.
sj-pdf-1-jct-10.1177_23800844211041911 – Supplemental material for Impact of Periodontal Disease on the Quality of Life of Older People in Indonesia: A Qualitative Study
Creators: name: Hijryana, M.
name: MacDougall, M.
name: Ariani, N.
name: Kusdhany, L.S.
name: Walls, A.W.G.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-jct-10.1177_23800844211041911 for Impact of Periodontal Disease on the Quality of Life of Older People in Indonesia: A Qualitative Study by M. Hijryana, M. MacDougall, N. Ariani, L.S. Kusdhany and A.W.G. Walls in JDR Clinical & Translational Research
Additional file 3 of Factorial validity and comparability of the six translations of the Rivermead Post-Concussion Symptoms Questionnaire translations: results from the CENTER-TBI study
Creators: name: Zeldovich, Marina
name: Bockhop, Fabian
name: Covic, Amra
name: Mueller, Isabelle
name: Polinder, Suzanne
name: Mikolic, Ana
name: van der Vlegel, Marjolein
name: von Steinbuechel, Nicole
Publisher: name: figshare
Year: 2024
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: Additional file 3. Supplementary figures S2.
BLOKCHEYN TEXNOLOGIYASINING ASOSIY KOMPONENTLARI
Creators: name: Qodirov, Farrux
name: Numonova, Hulkar
Publisher: name: Zenodo
Year: 2025

description: Blokcheyn – bu markazlashmagan va o‘zgartirib bo‘lmaydigan ma’lumotlar bazasi bo‘lib, tranzaksiyalarni xavfsiz va shaffof tarzda saqlashni ta’minlaydi. Ushbu texnologiya turli sohalarda qo‘llanilmoqda va uning samarali ishlashi bir nechta asosiy komponentlarga bog‘liq. Blokcheynning asosiy komponentlari quyidagilardan iborat: tugunlar (nodes) – tarmoqning ajralmas qismi bo‘lib, har bir tugun blokcheynning nusxasini saqlaydi; tranzaksiyalar (transactions) – foydalanuvchilar tomonidan amalga oshiriladigan operatsiyalar; bloklar (blocks) – tranzaksiyalarni o‘z ichiga olgan ma’lumotlar tuzilmasi. Har bir blok oldingi blok bilan bog‘langan bo‘lib, bu butun zanjirning yaxlitligini ta’minlaydi. Blokcheynning xavfsizligi va ishonchliligini ta’minlovchi muhim omillardan biri xesh funktsiyasi (hash function) bo‘lib, u tranzaksiya ma’lumotlarini shifrlaydi va har bir blokga noyob identifikator beradi. Konsensus mexanizmi (consensus mechanism) esa tarmoq ishtirokchilarining tranzaksiyalarni tekshirish va tasdiqlash jarayonida kelishib olishini ta’minlaydi. Eng mashhur konsensus mexanizmlari Proof of Work (PoW) va Proof of Stake (PoS) hisoblanadi.
sj-docx-1-hpp-10.1177_15248399211039796 – Supplemental material for Body Mapping and Story Circles in Sexual Health Research With Youth of Color: Methodological Insights and Study Findings From Adolescent X, an Art-Based Research Project
Creators: name: Brodyn, Adriana
name: Lee, Soo Young
name: Futrell, Elizabeth
name: Bennett, Ireashia
name: Bouris, Alida
name: Jagoda, Patrick
name: Gilliam, Melissa
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-hpp-10.1177_15248399211039796 for Body Mapping and Story Circles in Sexual Health Research With Youth of Color: Methodological Insights and Study Findings From Adolescent X, an Art-Based Research Project by Adriana Brodyn, Soo Young Lee, Elizabeth Futrell, Ireashia Bennett, Alida Bouris, Patrick Jagoda and Melissa Gilliam in Health Promotion Practice
Disegni di architettura dal Grand Tour. La collezione di John Stuart, III conte di Bute.
Creators: name: MARTIGNAGO, KATIA
Publisher: name: Universit� IUAV di Venezia
Year: 2021

description: Sebbene molti aspetti del Grand Tour siano stati ampiamente indagati, il mercato dei disegni d?architettura ad esso legato, e pi� in generale del Settecento, resta ancora da approfondire. L?obiettivo di questo studio � stato quindi quello di indagare quali prodotti, tra i disegni di architettura, fossero disponibili al viaggiatore, per lo pi� straniero, giunto in Italia e i loro meccanismi di produzione e commercio.
Il caso studio prescelto � stata la collezione di John Stuart, III conte di Bute. Questi, mentore e primo ministro di Giorgio III, tra la fine del 1768 e l?aprile del 1771 trascorse due soggiorni in Italia, durante i quali mise insieme una grande raccolta di disegni di architettura. I disegni si conservano dal 2001 al Victoria & Albert Museum di Londra in quindici album comprendenti 688 fogli raffiguranti architetture italiane. La tesi, oltre a fornire un catalogo dei disegni in gran parte inediti, studia la collezione con uno sguardo d?insieme, considerandola come un prodotto culturale unitario, indipendentemente dal valore del singolo foglio in quanto documento pi� o meno attendibile per lo studio delle vicende dell?edificio che rappresentano. L?ampiezza e la variet� che caratterizzano la collezione di Lord Bute hanno cos� permesso di ottenere uno sguardo sulla produzione e sul mercato di questa tipologia di materiale grafico in diverse aree d?Italia nella seconda met� del Settecento. Ne emerge un panorama variegato in cui era possibile acquistare sia disegni prodotti serialmente, e quindi pi� volte ricopiati, che disegni eseguiti su richiesta del committente. A eseguirli erano architetti che in molti casi legarono la propria carriera non al campo dell?ars aedificatoria, ma a quello della grafica, spesso connesso all?editoria. Il tramite tra questi professionisti e gli acquirenti erano per lo pi� ciceroni o altre figure preposte all?accoglienza degli stranieri in Italia, come i rappresentanti diplomatici. Si tratta per lo pi� di rappresentazione non precise, che fungevano piuttosto da ricordo - souvernir- idealizzato delle architetture visitate in Italia. Il loro prezzo era maggiore rispetto a quello delle incisioni prodotte per lo stesso mercato, ma nonostante ci� ad acquistarli, seppur in numero diverso, erano tutte le classi sociali che intraprendevano il Grand Tour: artisti, membri della classe media e aristocratici. I britannici -che erano i viaggiatori pi� numerosi- erano i destinatari privilegiati di questa produzione, come testimoniano iscrizioni e unit� di misura espresse in lingua inglese presenti sui disegni. Infatti, seppur la collezione di Lord Bute spicchi per la sua ampiezza e ricchezza di materiale, altri suoi connazionali assemblarono analoghi musei cartacei per testimoniare l?arte e l?architettura italiane.
Additional file 2 of Factorial validity and comparability of the six translations of the Rivermead Post-Concussion Symptoms Questionnaire translations: results from the CENTER-TBI study
Creators: name: Zeldovich, Marina
name: Bockhop, Fabian
name: Covic, Amra
name: Mueller, Isabelle
name: Polinder, Suzanne
name: Mikolic, Ana
name: van der Vlegel, Marjolein
name: von Steinbuechel, Nicole
Publisher: name: figshare
Year: 2024
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: Additional file 2. Supplementary figures S1.