cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(4067) Florence Grace Fraser
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Ácido hialurônico para tendinopatia do manguito rotador: revisão sistemática
Creators: name: Westphal Correa, Joel
name: Bueno, Anna Carolina
name: Lima, Ewerton Borges de Souza
name: Pochini, Alberto de Castro
name: Biruel, Elisabeth Peres
Publisher: name: Zenodo
Year: 2023
Subjects: Injections
Hyaluronic Acid
Rotator Cuff
soft tissue injuries
diagnostic imaging
Tendinopatias

description: Determinar a efetividade da infiltração com ácido hialurônico para tendinopatia do manguito rotador, guiado por ecografia
description: Centro de Traumato-Ortopedia do Esporte (CETE)
Synthesis of Ultra-Thin Superionic Cu2Se and New Aspects of the Low-Temperature Crystal Configurations
Creators: name: Suleiman, Abdulsalam Aji
name: Parsi, Amir
name: Razeghi, Mohammadali
name: Başçı, Uğur
name: Oh, Saeyoung
name: Pehlivanoğlu, Doruk
name: Jeoung, Hu Young
name: Kang, Kibum
name: Kasırga, T. Serkan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Superionic conductors offer unique advantages for novel technological devices in various fields, such as energy storage and neuromorphic computing. Above 414 K, Cu2Se turns into a well-known superionic conductor via a phase transition, and it is demonstrated to exhibit peculiar electrical and thermoelectric properties in bulk. Here, we report a large-area synthesis of ultra-thin single crystalline Cu2Se using the chemical vapor deposition method. We demonstrate that Cu2Se crystals exhibit optically and electrically controllable robust phase reconfiguration below 414 K. Moreover, our results show that the mobility of the liquid-like Cu ion vacancies in Cu2Se causes macroscopic fluctuations in the Cu ordering. Consequently, phase variations are not dictated by the diffusive motion of the ions but by the local energy minima formed due to the interplay between the extrinsic and the intrinsic material parameters. As a result, long-range ordering of the crystal below 414 K is optically observable at a micrometer scale. Our results show that Cu2Se could find applications beyond thermoelectric such as smart optical coatings, optoelectronic switching, and ionic transistors.
Titanoderma trochanter(Bory) Benhissoune, Boudouresque,Perret Boudouresque et Verlaque, et Titanoderma ramosissimum(Heydrich) comb. nov. (Corallinales, Rhodophytes), une redéfinition
Creators: name: BRESSAN, Uido
name: CABIOCH, Jacqueline
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2004

description: Titanoderma trochanter (Bory) Benhissoune, Boudouresque, Perret-Boudouresque et Verlaque, et Titanoderma
 ramosissimum (Heydrich) comb. nov. (Corallinales, Rhodophyta), a reassessment. Two partly branched Corallinales from
 the Mediterranean have been confused during a long time under the name Lithophyllum byssoides, now erroneous. Forty
 years ago, a first tentative dissociation taking into account only the external morphology remained unadopted. Examining
 new samples together with an investigation of type collections led to identify and separate clearly two species Titanoderma
 trochanter and Titanoderma ramosissimum through anatomical and reproductive features.
SOME NEW INTERSTITIAL HARPACTICOID COPEPODS FROM ANDHRA COAST, INDIA
Creators: name: RAO, G. Chandrasekhara
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1972

description: The paper describes five new species of interstitial harpacticoid copepods collected in winter 1968 from the intertidal sands on Andhra coast (Bay of Bengal). They are Hastigerella bengalensis sp. nov., Balucopsylla similis gen. et sp. nov., Paraleptomesochra wellsi sp. nov., Parapseudoleptomesochra (?) reductus sp. nov. and Sicameiralangi sp. nov.
Additional file 3 of Potential benefits of a virtual, home-based combined exercise and mindfulness training program for HSC transplant survivors: a single-arm pilot study
Creators: name: Ma, David D. F.
name: Fennessy, Kate
name: Kliman, David
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 3: Completed CERT Checklist with details of exercise intervention.
Fluoride Induces Endoplasmic Reticulum Stress in Ameloblasts Responsible for Dental Enamel Formation
Creators: name: Young, Conan S.
name: Tsuchiya, Masahiro
name: Everett, Eric T.
name: Nguyen, Linh
name: Martinez-Mier, Esperanza A.
name: Snead, Malcolm L.
name: Urano, Fumihiko
name: Kubota, Kaori
name: Lee, Daniel H.
name: Bartlett, John D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: The mechanism of how fluoride causes fluorosis remains unknown. Exposure to fluoride can inhibit protein synthesis, and this may also occur by agents that cause endoplasmic reticulum (ER) stress. When translated proteins fail to fold properly or become misfolded, ER stress response genes are induced that together comprise the unfolded protein response. Because ameloblasts are responsible for dental enamel formation, we used an ameloblast-derived cell line (LS8) to characterize specific responses to fluoride treatment. LS8 cells were growth-inhibited by as little as 1.9-3.8 ppm fluoride, whereas higher doses induced ER stress and caspase-mediated DNA fragmentation. Growth arrest and DNA damage-inducible proteins (GADD153/CHOP, GADD45alpha), binding protein (BiP/glucose-responsive protein 78 (GRP78), the non-secreted form of carbonic anhydrase VI (CA-VI), and active X-box-binding protein-1 (Xbp-1) were all induced significantly after exposure to 38 ppm fluoride. Unexpectedly, DNA fragmentation increased when GADD153 expression was inhibited by short interfering RNA treatment but remained unaffected by transient GADD153 overexpression. Analysis of control and GADD153(-/-) embryonic fibroblasts demonstrated that caspase-3 mediated the increased DNA fragmentation observed in the GADD153 null cells. We also demonstrate that mouse incisor ameloblasts are sensitive to the toxic effects of high dose fluoride in drinking water. Activated Ire1 initiates an ER stress response pathway, and mouse ameloblasts were shown to express activated Ire1. Ire1 levels appeared induced by fluoride treatment, indicating that ER stress may play a role in dental fluorosis. Low dose fluoride, such as that present in fluoridated drinking water, did not induce ER stress.
ANNELIDES POLYCHÈTES RECUEILLIES SUR LES PENTES DU TALUS CONTINENTAL, AU LARGE DE LA GALICE (ESPAGNE). CAMPAGNES 1967 ET 1968 DE LA « THALASSA »
Creators: name: AMOUREUX, Louis
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1972

description: 1200 Polychaetous worms at the bathyal level, coming from the coasts of Galicia (in Spain) are here analysed. 126 species are counted, a list of which is given. Among them is a new species with 51 examples, the diagnosis of which is given: Nothria hispánica (Eunicidae, Onuphinae). Another species, until now known through very rare specimens is here found again an re-described on the basis of 21 examples :
Parasthenelais hibernica (Mc Intosh) 1876. 10 other species were not shown in the « Faune de France » by P. Fauvel.
Cylinders in del Pezzo surfaces
Creators: name: Cheltsov, Ivan
name: Park, Jihun
name: Won, Joonyeong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: On del Pezzo surfaces, we study effective ample $\mathbb{R}$-divisors such that the complements of their supports are isomorphic to $\mathbb{A}^1$-bundles over smooth affine curves.
description: 33 pages. Gaps in the proofs of Theorems 4.1.1 and 4.1.3 in the previous version have been filled up
Who plays a musical instrument in elementary school? (Nicht jedes Kind spielt (irgend-)ein Instrument: Der familiäre Hintergrund als Determinante der Wahl von Musikinstrumenten im Grundschulalter) - study 2
Creators: name: Wießnet, Verena
name: Penthin, Marcus
name: Kröner, Stephan
name: Fritzsche, Eva
Publisher: name: Open Science Framework
Year: 2018

description: Playing a musical instrument requires economic capital and represents cultural capital. Thus, the odds to play an instrument are low for children from low-capital families. Moreover, if low-capital children are musically active, they should choose instruments providing lower distinction values. Thus, we investigated how economic capital (via International Socioeconomic Index of Occupation, ISEI) and music-related cultural capital (via parental musical activity) act together in explaining (a) whether children play any musical instrument and (b) explain the choice of classical vs. other vs. no musical instrument. We surveyed n = 685 students (Mage = 9.88, SD = 0.52, 50.1 % girls) from 16 elementary schools. Logistic regression (χ2 (2) = 93.94, p ≤ .01, n = 653; correctly classifying 60.2 % of the cases) showed that the odds of child musical activity increased both with parental ISEI (odds ratio for ten point ISEI-increment = 1.03, Wald χ2 (1) = 29.59, p ≤ 01) and parental musical activity (odds ratio = 3.02, Wald χ2 (1) = 35.70, p ≤ .01. Moreover, playing an instrument related to classical music was associated with both a higher parental ISEI (F(2, 659) = 33.95, p < .001; η2 = .09) and parental musical activity. Implications of our results for equal access to musical activities are discussed.
On three new Bathyporeia species from the Atlantic coasts of North Africa (Crustacea, Amphipoda, Pontoporeiidae)
Creators: name: D'ACOZ, Cédric D'UDEKEM
name: MENIOUI, Mohamed
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2004

description: Three new amphipods of the genus Bathyporeia are described from the Atlantic coasts of North Africa : B. elkaimi
 sp. nov., B. ledoyeri sp. nov., and B. microceras sp. nov. Both B. elkaimi sp. nov. and B. ledoyeri sp. nov. belong to the pilosa
 group : the carpal fang of their third and fourth pereiopods are blunt-tipped with a subapical setule, and they have no tooth
 on their coxae 1-3 and on their third epimeral plate. B. microceras sp. nov. is unrelated to any previously described species
 and adult males have very short second antennae.
(4066) Margaret Evangeline Fraser
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 4 of Potential benefits of a virtual, home-based combined exercise and mindfulness training program for HSC transplant survivors: a single-arm pilot study
Creators: name: Ma, David D. F.
name: Fennessy, Kate
name: Kliman, David
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 4: Fig. S1. Participant scores on the Godin-Shepard Leisure Time Questionnaire, where higher scores indicate greated self-reported use of leisure time. Fig. S2. Participant scores on the Pittsburgh Sleep Quality Index (PQSI) where lower scores indicate improvements in sleep quality. Fig. S3. Participant scores on the Hospital Anxiety and Depression Scale (HADS) anxiety subscale, where reduced scores indicate improvements in self-reported symptoms of anxiety.Supplementary Fig. S4. Participant scores on the Hospital Anxiety and Depression Scale (HADS) depression subscale, where reduced scores indicate improvements in self-reported symptoms of depression. Fig. S5. Six-point Likert scale from questionnaire evaluating patient feedback at 6-months post training. Q1- Was the MBSM useful? Q2- Was the exercise component useful? Q3- Did MBSM change your practice? Q4- Did exercise change your habits? Q5- How do you rate telehealth (video) as a method of service provision? Q6- How would you rate the quality of service if it was a part of your treatment? Q7- Do you feel that your participation has been worthwhile?
Normal and Cystic Fibrosis Airway Surface Liquid Homeostasis: THE EFFECTS OF PHASIC SHEAR STRESS AND VIRAL INFECTIONS
Creators: name: Button, Brian
name: Boucher, Richard C.
name: Pickles, Raymond J.
name: Paradiso, Anthony M.
name: Collins, Peter L.
name: Tarran, Robert
name: Fredberg, Jeffrey J.
name: Picher, Maryse
name: Lazarowski, Eduardo R.
name: Ribeiro, Caria M.
name: Zhang, Liqun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: Mammalian airways normally regulate the volume of a thin liquid layer, the periciliary liquid (PCL), to facilitate the mucus clearance component of lung defense. Studies under standard (static) culture conditions revealed that normal airway epithelia possess an adenosine-regulated pathway that blends Na+ absorption and Cl− secretion to optimize PCL volume. In cystic fibrosis (CF), the absence of CF transmembrane conductance regulator results in a failure of adenosine regulation of PCL volume, which is predicted to initiate mucus stasis and infection. However, under conditions that mimic the phasic motion of the lung in vivo, ATP release into PCL was increased, CF ion transport was rebalanced, and PCL volume was restored to levels adequate for lung defense. This ATP signaling system was vulnerable, however, to insults that trigger CF bacterial infections, such as viral (respiratory syncitial virus) infections, which up-regulated extracellular ATPase activity and abolished motion-dependent ATP regulation of CF PCL height. These studies demonstrate (i) how the normal coordination of opposing ion transport pathways to maintain PCL volume is disrupted in CF, (ii) the hitherto unknown role of phasic motion in regulating key aspects of normal and CF innate airways defense, and (iii) that maneuvers directed at increasing motion-induced nucleotide release may be therapeutic in CF patients.
Informasi yang Berlebihan
Creators: name: Ramadhani, Alliefyah
Publisher: name: Zenodo
Year: 2023
Subjects: Informasi

description: Dengan adanya pergeseran menuju masyarakat berbasis informasi dan desentralisasi informasi, informasi yang berlebihan telah menarik minat yang semakin besar dalam komunitas penelitian komputer dan ilmu informasi. Namun, tidak ada pemahaman yang jelas mengenai arti dari istilah ini, dan meskipun telah banyak definisi yang diusulkan, tidak ada kesepakatan Bersama. Tema-tema yang diidentifikasi dari analisis konsep penulis menemukan pemicu yang berkaitan dengan karakteristik informasi, kebutuhan informasi, lingkungan kerja, kemampuan kognitif individu dan lingkungan informasi. Temuan ini memungkinkan mereka untuk memberikan definisi tentang kelebihan informasi.
description: Tugas Resensi
The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor α-, and Mycobacterium tuberculosis -induced Pro-inflammatory Signals
Creators: name: Duncan, Joseph A.
name: Lich, John D.
name: Moore, Christopher
name: Williams, Kristi L.
name: Vogel, Stefanie N.
name: Su, Lishan
name: Ting, Jenny P.Y.
name: Kurtz, Sherry
name: Braunstein, Miriam
name: Rallabhandi, Prasad
name: Accavitti-Loper, Mary A.
name: Reed, William
name: McNeil Coffield, V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2005

description: The CATERPILLER (CLR, also NOD and NLR) proteins share structural similarities with the nucleotide binding domain (NBD)-leucine-rich repeat (LRR) superfamily of plant disease-resistance (R) proteins and are emerging as important immune regulators in animals. CLR proteins contain NBD-LRR motifs and are linked to a limited number of distinct N-terminal domains including transactivation, CARD (caspase activation and recruitment), and pyrin domains (PyD). The CLR gene, Monarch-1/Pypaf7, is expressed by resting primary myeloid/monocytic cells, and its expression in these cells is reduced by Toll-like receptor (TLR) agonists tumor necrosis factor (TNF) α and Mycobacterium tuberculosis. Monarch-1 reduces NFκB activation by TLR-signaling molecules MyD88, IRAK-1 (type I interleukin-1 receptor-associated protein kinase), and TRAF6 (TNF receptor (TNFR)-associated factor) as well as TNFR signaling molecules TRAF2 and RIP1 but not the downstream NFκB subunit p65. This indicates that Monarch-1 is a negative regulator of both TLR and TNFR pathways. Reducing Monarch-1 expression with small interference RNA in myeloid/ monocytic cells caused a dramatic increase in NFκB activation and cytokine expression in response to TLR2/TLR4 agonists, TNFα, or M. tuberculosis infection, suggesting that Monarch-1 is a negative regulator of inflammation. Because Monarch-1 is the first CLR protein that interferes with both TLR2 and TLR4 activation, the mechanism of this interference is significant. We find that Monarch-1 associates with IRAK-1 but not MyD88, resulting in the blockage of IRAK-1 hyperphosphorylation. Mutants containing the NBD-LRR or PyD-NBD also blocked IRAK-1 activation. This is the first example of a CLR protein that antagonizes inflammatory responses initiated by TLR agonists via interference with IRAK-1 activation.
Size Effects in the Ginzburg-Landau Theory
Creators: name: Fiolhais, Miguel C. N.
name: Birman, Joseph L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The Ginzburg-Landau theory is analyzed in the case of small dimension superconductors, a couple of orders of magnitude above the coherence length, where the theory is still valid but quantum fluctuations become significant. In this regime, the potential around the expectation value is approximated to a quadratic behavior, and the ground-state derived from the Klein-Gordon solutions of the Higgs-like field. The ground-state energy is directly compared to the condensation energy, and used to extract new limits on the size of superconductors at zero Kelvin and near the critical temperature.
description: 4 pages, 1 figure
Etude de la phénologie de la reproduction de la Rhodophyceae Palmaria palmatale long des côtes françaises de la Manche
Creators: name: LE GALL, Line
name: DENIAUD, Estelle
name: RUSIG, Anne-Marie
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2004

description: Phenological study of the reproduction of the Rhodophyceae Palmaria palmata along the French coast of the
 English Channel. In the rocky, intertidal level of the North Atlantic coast, Palmaria palmata is in terms of biomass, one of
 the most important Rhodophyceae. This economically interesting seaweed is harvested for several applications, and it is
 therefore important to evaluate algae stocks and to study population dynamics. Hence, a phenological study of four popu-
 lations of P. palmata was undertaken along the french coast of the English Channel. We were able to establish that some
 sporophytic and male gametophytic plants were fertile in fall and winter, while the majority of plants remained sterile
 during the whole year. Data have shown wide variations between the three sites studied regarding timing and the capacity
 of annual reproduction. Thallus fertility occurs earlier in the Western part of the English Channel than in the Eastern part,
 which could be explained by the differing water temperature gradient. The annual reproduction capacity is high at Roscoff,
 medium at Cap Lévy and weak at St Aubin.
c-Src Control of Chloride Channel Support for Osteoclast HCl Transport and Bone Resorption
Creators: name: Xu, Weibing
name: Cohen, Christopher
name: Edwards, John C.
name: Schlesinger, Paul H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Bone degradation by osteoclasts depends upon active transport of hydrogen ions to solubilize bone mineral. This transport is supported by the parallel actions of a proton ATPase and a chloride channel located in the osteoclast ruffled membrane. We have previously identified a novel chloride channel, p62, which appears to be the avian counterpart to CLIC-5b and is expressed coincident with the appearance of acid secretion as avian osteoclasts differentiate in culture. In this article, we show that suppression of CLIC-5b in differentiating avian osteoclasts results in decreased acidification by vesicles derived from these cells and decreased ability of the cells to resorb bone. Acidification is rescued by the presence of valinomycin, consistent with a selective loss of chloride channel but not proton pump activity. Osteoclast bone resorption is known to be dependent on the expression of the tyrosine kinase, c-Src. We show that CLIC-5b from osteoclasts has affinity for both Src SH2 and SH3 domains. We find that suppression of expression of Src in developing osteoclasts results in decreased vesicular acidification, which is rescued by valinomycin, consistent with the loss of chloride conductance in the proton pump-containing vesicles. Suppression of c-Src causes no change in the steady state level of CLIC-5b expression, but does result in failure of proton pump and CLIC-5b to colocalize in cultured osteoclast precursors. We conclude that suppression of c-Src interferes with osteoclast bone resorption by disrupting functional co-localization of proton pump and CLIC-5b.
(4064) James Playfair
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Proportional Fair Scheduling Using Water-Filling Technique for SC-FDMA Based D2D Communication
Creators: name: Shah, Syed Tariq
name: Gu, Jaheon
name: Hasan, Syed Faraz
name: Chung, Min Young
Publisher: name: arXiv
Year: 2023
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The resource allocation in SC-FDMA is constrained by the condition that multiple subchannels should be allocated to a single user only if they are adjacent. Therefore, the scheduling scheme of a D2D-cellular system that uses SC-FDMA must also conform to the so-called adjacency constraint. This paper proposes a heuristic algorithm with low computational complexity that applies proportional fair (PF) scheduling in the D2D-cellular system. The proposed algorithm consists of two main phases: i) subchannel allocation and ii) adjustment of data rates, which are executed for both CUEs and DUEs. In the subchannel allocation phase for CUEs (or D2D pairs), the users' data rates are maximized via optimal power allocation to frequency-contiguous subchannels. In the second phase, a PF scheduling problem is solved to decide the modulation and coding scheme (MCS) of both CUEs and D2D pairs. Both phases of the proposed algorithm benefit from the Water-Filling (WF) technique. The simulation results suggest that the proposed scheme performs similarly to optimal PF scheduling from the perspective of users' data rate and their logarithmic sum. An additional benefit of the proposed scheme is its low computational overhead.
ProKnow: Process Knowledge for Safety Constrained and Explainable Question Generation for Mental Health Diagnostic Assistance
Creators: name: Roy, Kaushik
name: Gaur, Manas
name: Soltani, Misagh
name: Rawte, Vipula
name: Kalyan, Ashwin
name: Sheth, Amit
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Current Virtual Mental Health Assistants (VMHAs) provide counseling and suggestive care. They refrain from patient diagnostic assistance because they lack training in safety-constrained and specialized clinical process knowledge. In this work, we define Proknow as an ordered set of information that maps to evidence-based guidelines or categories of conceptual understanding to experts in a domain. We also introduce a new dataset of diagnostic conversations guided by safety constraints and Proknow that healthcare professionals use. We develop a method for natural language question generation (NLG) that collects diagnostic information from the patient interactively. We demonstrate the limitations of using state-of-the-art large-scale language models (LMs) on this dataset. Our algorithm models the process knowledge through explicitly modeling safety, knowledge capture, and explainability. LMs augmented with ProKnow guided method generated 89% safer questions in the depression and anxiety domain. The Explainability of the generated question is assessed by computing similarity with concepts in depression and anxiety knowledge bases. Overall, irrespective of the type of LMs augmented with our ProKnow, we achieved an average 82% improvement over simple pre-trained LMs on safety, explainability, and process-guided question generation. We qualitatively and quantitatively evaluate the efficacy of the proposed ProKnow-guided methods by introducing three new evaluation metrics for safety, explainability, and process knowledge adherence.
(4065) Jane Speirs
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Molecular Mechanism of Membrane Docking by the Vam7p PX Domain
Creators: name: Setty, Thanuja Gangi
name: Burd, Christopher G.
name: Overduin, Michael
name: Cheever, Matthew L.
name: Stahelin, Robert V.
name: Cho, Wonhwa
name: Lee, Stephanie A.
name: Kutateladze, Tatiana G.
name: Kovacs, James
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The Vam7p t-SNARE is an essential component of the vacuole fusion machinery that mediates membrane trafficking and protein sorting in yeast. Vam7p is recruited to vacuoles by its N-terminal PX domain that specifically recognizes PtdIns(3)P in the bilayers, however the precise mechanism of membrane anchoring remains unclear. Here we describe a molecular basis for membrane targeting and penetration by the Vam7p PX domain based on structural and quantitative analysis of its interactions with lipids and micelles. Our results derived from in vitro binding measurements using NMR, monolayer surface tension experiments and mutagenesis reveal a multivalent membrane docking mechanism involving specific PtdIns(3)P recognition that is facilitated by electrostatic interactions and accompanying hydrophobic insertion. Both the hydrophobic and electrostatic components enhance the Vam7p PX domain association with PtdIns(3)P-containing membranes. The inserting Val70, Leu71, and Trp75 residues located next to the PtdIns(3)P binding pocket are surrounded by a basic patch, which is involved in nonspecific electrostatic contacts with acidic lipids, such as PtdSer. Substitution of the insertion residues significantly reduces the binding and penetrating power of the Vam7p PX domain and leads to cytoplasmic redistribution of the EGFP-tagged protein. The affinities of the PX domain for PtdIns(3)P and other lipids reveal a remarkable synergy within the multivalent complex that stably anchors Vam7p at the vacuolar membrane.
First record of Anadara transversa (Say, 1822) (Bivalvia: Arcidae) in the Bay of Biscay
Creators: name: FERNÁNDEZ-RODRÍGUEZ, Irene
name: BAÑÓN, Rafael
name: ANADÓN, Nuria
name: ARIAS, Andrés
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2016

description: The occurrence of the alien species Anadara transversa is reported for the first time in the Bay of Biscay, from two estuaries of northern Spain (Villaviciosa and Eo), constituting its northernmost distribution in E. Atlantic to date. We present a detailed diagnosis and illustrations of the species in order to facilitate its differentiation from other native ark clams and the introduced A. kagoshimensis. Furthermore, the potential pathways for its introduction in the area are discussed.
INFLUENCE DE CERTAINS FACTEURS EXTERNES ET INTERNES SUR LA DURÉE DU CYCLE D'INTERMUE, LE TAUX DE CROISSANCE ET LA TENEUR EN CENDRES DES EXUVIES DU CRUSTACÉ DÉCAPODE BRACHYOURE ERIOCHEIR SINENSIS H. MILNE-EDWARDS
Creators: name: DE LEERSNYDER, Monique
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1972

Abstract
INFLUENCE DE LA NATURE GRANULOMÉTRIQUE DES SÉDIMENTS SUR LES STRUCTURES BENTHIQUES. BAIES DE DOUARNENEZ ET D'AUDIERNE (OUEST-FINISTÈRE)
Creators: name: TOULEMONT, Anne
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1972

description: This is a study of the benthic ecology of two bays situated at the west end of Brittany.After a review of the geology and a detailed description of the sediments, the general distribution of infaunai sdescribed. The affinity between the communities and the character of the substrate is shown precisely through the use of the concept of «area-envelope». This method, applied to different species, conserves all the information obtained by grain-sizea nalyses; it permits an objective classification of stenotope and eurytope species. The communities were superimposed on Folk and Ward’smean/dispersion index diagramm.
Degenerate optomechanical parametric oscillators: cooling in the vicinity of a critical point
Creators: name: Degenfeld-Schonburg, Peter
name: Abdi, Mehdi
name: Hartmann, Michael J.
name: Navarrete-Benlloch, Carlos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Degenerate optomechanical parametric oscillators are optical resonators in which a mechanical degree of freedom is coupled to a cavity mode that is nonlinearly amplified via parametric down-conversion of an external pumping laser. Below a critical pumping power the down-converted field is purely quantum-mechanical, making the theoretical description of such systems very challenging. Here we introduce a theoretical approach that is capable of describing this regime, even at the critical point itself. We find that the down-converted field can induce significant mechanical cooling and identify the process responsible of this as a cooling-by-heating mechanism. Moreover, we show that, contrary to naive expectations and semi-classical predictions, cooling is not optimal at the critical point, where the photon number is largest. Our approach opens the possibility for analyzing further hybrid dissipative quantum systems in the vicinity of critical points.
description: We will appreciate comments and (constructive) criticism
OBSERVATION AU MICROSCOPE A BALAYAGE DE QUELQUES GASTROTRICHES CHAETONOTOIDES
Creators: name: LUPORINI, P.
name: TONGIORGI, P.
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1972

description: On several Chaetonotoid Gastrotrichs observed by the scanning electron microscope.
The cuticular specializations of three species of Chaetonotoids Gastrotrichs have been studied by the scanning electron microscope. This technique facilitates the study of morphological peculiarities useful in taxonomical research. Chaetonatus batillifer n.sp., is described as a new species, because of the peculiar shape of its lateral paddles.
Infectious bursal disease virus in Western Europe: the rise of reassortant strains as the dominant field threat
Creators: name: Legnardi, Matteo
name: Franzo, Giovanni
name: Tucciarone, Claudia Maria
name: Koutoulis, Konstantinos
name: Cecchinato, Mattia
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 60506 Virology

description: Infectious bursal disease virus (IBDV) is a highly contagious birnavirus causing a burdensome immunosuppressive disease in chickens. IBDV features a remarkable antigenic, pathogenic and genetic heterogeneity, with significant implications on disease manifestation, control measures and diagnostic approaches. The recent proposals of comprehensive phylogenetic classification systems offered the ideal platform for large-scale molecular surveys, which are crucial to gather epidemiological data and inform control efforts. In this study, the IBDV scenario was investigated in most of Western Europe by considering the results of diagnostic activities performed internationally throughout 2021. In total, 470 bursal samples from nine different countries were analysed by RT–PCR targeting the VP2. When a field virus was identified, the VP1 was also characterized. Most of the 132 detected field viruses were highly homologous reassortants featuring a very virulent-like VP2 and a classical-like VP1 (genotype A3B1). Despite emerging recently, these reassortants were already signalled in several countries in North-Western Europe and associated with subclinical infections. Here, we report their further spread in the region, where they currently represent the dominant field threat. Two other IBDV types were found, one in Italy, where all the identified viruses clustered in a clade of the A3B1 genotype previously reported only in Russia and the Middle East, and the other in Portugal, where the recently characterized A9B1 genotype was confirmed to circulate. The obtained data suggest the recent occurrence of a major shift in the Western European epidemiological landscape of IBDV, stressing the importance of steady monitoring and sharing of information among different countries and laboratories. RESEARCH HIGHLIGHTSThe IBDV scenario in Western Europe seems to have radically changed in recent years.IBDV reassortants were found to be the dominant field type in the region.Local circulation of two other IBDV types was detected in Italy and Portugal. The IBDV scenario in Western Europe seems to have radically changed in recent years. IBDV reassortants were found to be the dominant field type in the region. Local circulation of two other IBDV types was detected in Italy and Portugal.
Morphometric variation of fish scales among some species of the family Lutjanidae from Iranian waters
Creators: name: IBÁÑEZ, Ana L.
name: JAWAD, Laith A.
name: SADIGHZADEH, Zahra
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2016

description: We used geometric morphometric methods on shape of fish scales to assess differences in shape among species and genera. We also compared the method with traditional phylogenetic approaches. Scale form was described using five landmarks, the coordinates of which were subjected to generalized Procrustes analysis, followed by principal component analysis. Cross validated discriminant analysis was used to assess and compare the efficacy of shape and relative warp in size-shape space (centroid size plus shape variables). The cross-validated canonical discriminant analysis correctly classified 79.0% for genus. Most misclassifications occurred between the Lutjanus species, with only 76.7% of correct classifications (especially with the genus Pristipomoides), whereas the genera Pinjalo and Pristipomoides showed 100.0% and 76.9% of correct classification, respectively. The discrimination of species correctly classified ranged between 64.3% and 100.0%. The highest correct classification rates were found among species of the genera Pinjalo, and the Lutjanus johni and L. lutjanus species. Agreement could be found between scale shape and phylogenetic analysis.
Physiological Regulation of ATP Release at the Apical Surface of Human Airway Epithelia
Creators: name: Okada, Seiko F.
name: Nicholas, Robert A.
name: Boucher, Richard C.
name: Kreda, Silvia M.
name: Lazarowski, Eduardo R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Extracellular ATP and its metabolite adenosine regulate mucociliary clearance in airway epithelia. Little has been known, however, regarding the actual ATP and adenosine concentrations in the thin (~7 μm) liquid layer lining native airway surfaces and the link between ATP release/metabolism and autocrine/paracrine regulation of epithelial function. In this study, chimeric Staphylococcus aureus protein A-luciferase (SPA-luc) was bound to endogenous antigens on primary human bronchial epithelial (HBE) cell surface and ATP concentrations assessed in real-time in the thin airway surface liquid (ASL). ATP concentrations on resting cells were 1–10 nM. Inhibition of ecto-nucleotidases resulted in ATP accumulation at a rate of ~250 fmol/min/cm2, reflecting the basal ATP release rate. Following hypotonic challenge to promote cell swelling, cell-surface ATP concentration measured by SPA-luc transiently reached ~1 μM independent of ASL volume, reflecting a transient 3-log increase in ATP release rates. In contrast, peak ATP concentrations measured in bulk ASL by soluble luciferase inversely correlated with volume. ATP release rates were intra-cellular calcium-independent, suggesting that non-exocytotic ATP release from ciliated cells, which dominate our cultures, mediated hypotonicity-induced nucleotide release. However, the cystic fibrosis transmembrane conductance regulator (CFTR) did not participate in this function. Following the acute swelling phase, HBE cells exhibited regulatory volume decrease which was impaired by apyrase and facilitated by ATP or UTP. Our data provide the first evidence that ATP concentrations at the airway epithelial surface reach the range for P2Y2 receptor activation by physiological stimuli and identify a role for mucosal ATP release in airway epithelial cell volume regulation.
Comparative study of TESS photometry and radial velocities on six early K-type contact binaries with similar periods around 0.268 days
Creators: name: Liu, N. -P.
name: Qian, S. -B.
name: Liao, W. -P.
name: Huang, Y.
name: Yuan, Z. -L.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: High-precision light curves were extracted from TESScut images. Together with APOGEE and LAMOST medium resolution spectra, a joint study was made for six early K-type contact binary candidates selected unbiasedly with orbital periods around 0.268 days. It is found that all of them (RV CVn, EK Com, V384 Ser, V1038 Her, EH CVn, and CSS$\_$J125403.7+503945) are W-subtype shallow contact systems though with different mass ratios ($1/q$ = 0.27--0.62). The effective temperature differences between binary components are around a few hundred Kelvins. The original definition of A- and W-subtypes were compared with the customarily used methods which rely on the shape or on the photometric solutions of light curves. The latter two methods are not always reliable and therefore the radial velocity analysis is strongly recommended. Through a collection of all available K-type contact binaries with both photometric and spectroscopic measurements, it is found that almost all of them are W-subtype systems, except a few objects which have nearly identical temperatures for binary components. This W-subtype phenomenon for K-type contact binaries should be further checked with more samples in the future. Finally, the physical parameters of the targets were determined with joint data analysis and the multiplicity is discussed for these targets. V384 Ser and RV CVn are confirmed very likely to be triple systems from comprehensive analysis, while V1038 Her is a candidate of a triple system based on photometric and spectroscopic solutions.
Additional file 1 of Comparison of image quality and spatial resolution between 18F, 68Ga, and 64Cu phantom measurements using a digital Biograph Vision PET/CT
Creators: name: Braune, Anja
name: Oehme, Liane
name: Freudenberg, Robert
name: Hofheinz, Frank
name: van den Hoff, Jörg
name: Kotzerke, Jörg
name: Hoberück, Sebastian
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1: Transversal (left), coronal (middle), and sagittal plane of the NEMA PET body phantom filled with 18F-FDG and illustration of the regions of interest.
Contribution to the knowledge of the biology of the spider crab Maja crispata Risso, 1827 (Crustacea: Decapoda: Majidae) along the Tunisian coasts, Mediterranean Sea
Creators: name: RABAOUI, Lotfi
name: BEN BRAHIM, Hanéne
name: EL ZRELLI, Radhouan
name: MANSOUR, Lamjed
name: TLIG-ZOUARI, Sabiha
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2016

description: The present work is a first contribution to the knowledge of the biology of the spider crab Maja crispata along the Tunisian coasts, with particular reference to the sex-ratio and size (carapace width) structure as well as the morphometric characterization of six subpopulations living in both south-eastern (Gulf of Gabes) and northern (Gulf of Tunis) coasts of Tunisia. Results of this study showed that the Tunisian population of M. crispata is generally male-biased with some spatial variations of the sex-ratio, probably due to the migratory behavior of the species. The comparative analysis of size structures of all studied subpopulations highlighted also some spatial variations, with a unimodal size distribution and a clear prevalence of individuals belonging to the size class of 35-40 mm. Concerning the morphometric characterization of M. crispata, the principal component analysis showed a main separation of the spider crabs examined with respect to the gender. Based on the dendrogram of hierarchic classification, a separation was also highlighted with respect to sampling sites and regions. The spatial variations of the sex-ratio, size structure and morphometry features of M. crispata could be due to the spatial variations of environmental factors (e.g. temperature, trophic resources) that may influence the biology of the species.
(4068) Selina Torrence Fraser
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Linear response for intermittent maps
Creators: name: Baladi, V.
name: Todd, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Dynamical Systems (math.DS)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 37C40, 37C30, 37E05

description: We consider the one parameter family $α\mapsto T_α$ ($α\in [0,1)$) of Pomeau-Manneville type interval maps $T_α(x)=x(1+2^αx^α)$ for $x \in [0,1/2)$ and $T_α(x)=2x-1$ for $x \in [1/2, 1]$, with the associated absolutely continuous invariant probability measure $μ_α$. For $α\in (0,1)$, Sarig and Gouëzel proved that the system mixes only polynomially with rate $n^{1-1/α}$ (in particular, there is no spectral gap). We show that for any $ψ\in L^q$, the map $α\to \int_0^1 ψ\, dμ_α$ is differentiable on $[0,1-1/q)$, and we give a (linear response) formula for the value of the derivative. This is the first time that a linear response formula for the SRB measure is obtained in the setting of slowly mixing dynamics. Our argument shows how cone techniques can be used in this context. For $α\ge 1/2$ we need the $n^{-1/α}$ decorrelation obtained by Gouëzel under additional conditions.
description: Minor typos corrected. To appear in Comm. Math. Phys
PTP-PEST Couples Membrane Protrusion and Tail Retraction via VAV2 and p190RhoGAP
Creators: name: Sastry, Sarita K.
name: Tremblay, Michel L.
name: Cote, Jean Francois
name: Liu, Betty P.
name: Burridge, Keith
name: Rajfur, Zenon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Cell motility is regulated by a balance between forward protrusion and tail retraction. These phenomena are controlled by a spatial asymmetry in signals at the front and the back of the cell. We show here that the protein-tyrosine phosphatase, PTP-PEST, is required for the coupling of protrusion and retraction during cell migration. PTP-PEST null fibroblasts, which are blocked in migration, exhibit exaggerated protrusions at the leading edge and long, unretracted tails in the rear. This altered morphology is accompanied by changes in the activity of Rho GTPases, Rac1 and RhoA, which mediate protrusion and retraction, respectively. PTP-PEST null cells exhibit enhanced Rac1 activity and decreased RhoA activity. We further show that PTP-PEST directly targets the upstream regulators of Rac1 and RhoA, VAV2 and p190RhoGAP. Moreover, we demonstrate that the activities of VAV2 and p190RhoGAP are regulated by PTP-PEST. Finally, we present evidence indicating the VAV2 can be regulated by integrin-mediated adhesion. These data suggest that PTP-PEST couples protrusion and retraction by acting on VAV2 and p190RhoGAP to reciprocally modulate the activity of Rac1 and RhoA.