cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Solvent-Free One-Pot Synthesis of Diverse Dihydropyrimidinones/Tetrahydropyrimidinones Using Biginelli Reaction Catalyzed by Fe3O4@C@OSO3H
Creators: name: Hatkehlouei, Seyedeh Fatemeh Taheri
name: Mirza, Behrooz
name: Soleimani-Amiri*, Somayeh
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: One-pot synthesis of 3,4-dihydropyrimidinone/thione and 3,4,5,6-tetrahydropyrimidinone/thione derivatives was successfully performed in high yields through the reaction of aromatic aldehyde, β-dicarbonyl, urea/thiourea using Fe3O4@C@OSO3H nano-catalyst under solvent-free conditions at 80 °C. Fe3O4@C@OSO3H was introduced as an efficient magnetic nano-catalyst in Biginelli condensation with powerful reusability. The great yield of products, fast reaction time, simple work-up procedure, as well as usage of nontoxic, reusable, and easily recoverable catalyst with an external magnet was counted as advantages of the applied process. The magnetic nano-catalyst was removed after reaction completion and reused seven times at the same conditions without significant decay in catalyst activity. The magnetic nano-catalyst was synthesized through a simple and inexpensive two steps method and characterized by FT-IR, EDX, SEM, TEM, DLS, XRD, and VSM techniques.
Design and Synthesis of 3,6-Disubstituted- and 2,3,6-Trisubstitutedquinoxalines: Docking and In Vitro Antimicrobial Study
Creators: name: Ismail, Magda M. F.
name: El-Sehrawi, Hend M. A.
name: Khalifa, Maha M.
name: Harras, Marwa F.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Antimicrobial chemotherapy is the clinical application of antimicrobial agents to treat infectious disease. A new series of 3,6-disubstituted- and 2,3,6-trisubstitutedquinoxalines have been synthesized by appropriate methods. All test compounds have been evaluated for in vitro antimicrobial activity. Further investigation using MIC experiment was performed; It appears that, compound 14c has higher broad-spectrum antibacterial activity (MIC= 0.01–0.24 ug/ml) than the reference drug, streptomycin (MIC= 0.03–0.97 ug/ml). As well, it elicited remarkable antifungal activity than the reference drug clotrimazole against almost all the selected strains. Moreover, docking study of the most active compounds into MurF active site has confirmed their binding affinity to MurF.
Rational Design, Synthesis and Evaluation of Novel Rodanine Derivatives for Antihyperglycemic Activity
Creators: name: Mandal, Subhankar P.
name: Reji, Anu
name: Bhavimani, Guru
name: Prabitha, P.
name: Durai, Priya
name: Yuvaraj, S.
name: Shashank, A.
name: Krishna, K. L.
name: Kumar, B. R. Prashantha
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: A new series of rhodanines with phenyl substitution at the fifth position of rhodanine ring were designed targeting the PPAR-γ receptor for their possible antihyperglycemic activity. The rational design and molecular modeling studies were performed against PPAR-γ (PDB ID: 2PRG). The compounds were docked and thereafter subjected for the synthesis via dithiocarbamate formation followed by Knoevenagel condensation. Structures were confirmed by IR, NMR and Mass spectral analysis. All synthesized compounds were screened for in vitro glucose uptake assay using isolated hepatocytes. The Compounds A5 and B5 having N-(p-methoxy benzyl) at third position of rhodanine ring showed good glucose uptake activity. These two compounds were further studied for the in vivo antihyperglycemic study against dexamethasone induced insulin resistance. The compounds were tested at single dose level of 10 mg/kg, per oral. The compound B5 showed significant antihyperglycemic activity when compared with the standard drug, pioglitazone. The illustration, about the molecular design, synthesis, analysis, glucose uptake study and in vivo antihyperglycemic activity is reported here along with the structure activity relationships. A series of N-Substituted rhodanines were synthesized by taking varied amines and aldehydes, via Knoevenagel condensation. The synthesized compounds were subjected to in vitro and in vivo glucose uptake assay. The compound showed comparable biological activity with reference to standard drug. Additionally, molecular docking and MD simulation study was performed to support the hypothesis.
Mechanochemical Approach for the Selective Synthesis of 1,2-Disubstituted Benzimidazoles and Their Molecular Docking Studies
Creators: name: Sahiba, Nusrat
name: Agarwal, Dinesh Kumar
name: Manhas, Anu
name: Sethiya, Ayushi
name: Soni, Jay
name: Jha, Prakash Chandra
name: Agarwal, Shikha
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 60506 Virology

description: A greener, scalable and mild mechanochemical protocol has been developed using readily available aromatic aldehydes and o-phenylenediamine in the presence of urea nitrate catalyst to afford 1,2-disubstituted benzimidazoles in few seconds. The highly efficient urea nitrate catalyzed synthesis proceeded via carbonyl activation-cyclization-atmospheric oxidation pathway. The method involved short reaction time (20–30 s), solvent free, easy preparation of catalyst, recyclable catalyst, easy isolation, high yield (92%–99%) at room temperature. Green chemistry matrix of synthesized compounds exhibited low e-factor (0.11), high atom-economy (90.74%), high reaction mass efficiency (89.9%) and excellent eco-score (78.5%). The molecular docking study of all the synthesized compounds for antibacterial and centromere associated protein inhibitor activity gave potential hits via presence of high interaction pattern. Compound 3b (−26.7009 kJ/mol) and 3k (−25.0285 kJ/mol) exhibited highest docking score with the selected 2XCS and 1T5C proteins, respectively.
Supplementary document for Integrated programmable fully-coupled three bus-ring resonator photonic molecule with ultra-low power piezo-electric control - 6342980.pdf
Creators: name: Blumenthal, Daniel
name: Wang, Jiawei
name: LIU, KAIKAI
name: Isichenko, Andrei
name: Rudy, Ryan
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Info
CARBGAME - ACID BASE BALANCE
Creators: name: Surapaneni, Krishna Mohan
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 320502
subject: Medical biochemistry - carbohydrates

description: CARBGAME is an interactive card and board game series designed to make learning biochemistry more engaging, collaborative, and clinically relevant for first year medical students. Developed as a response to common challenges faced in understanding foundational topics, the game transforms traditionally abstract content into an active learning experience through structured play. By combining case-based questions, team discussion, and strategy elements, CARBGAME encourages students to think critically, apply concepts in context, and develop confidence in approaching difficult subject areas.
Pd2dba3/P(t-Bu)3H.BF4/Cy2NMe Catalyzed Heck Coupling in Synthesis of 3-Alkenyl-1H-Isochromen-1-Ones
Creators: name: Dasaradhan, Changalaraya
name: Khan, Fazlur-Rahman Nawaz
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology

description: An efficient catalytic system comprising of Pd2dba3/P(t-Bu)3H.BF4/Cy2NMe –for the Heck coupling in the synthesis of 3-alkenyl isochromen-1-ones, 3 has been developed. Air stable alkyl phosphonium salt, [(t-Bu)3Ph]BF4 was found to be vital for the activation of 3- chloroisochromen-1-ones, 1 in regio-selective Heck coupling reactions. The technique has additionally been reached out to typharin, penicilisorin and artemidin analogs.
Building a Robust and Representative Wildland Fire Mitigation and Management Workforce
Creators: name: Varney, Abigail
name: Jurenci, Cassandra
Publisher: name: Stanford Digital Repository
Year: 2024
Subjects: wildfire, workforce, cepp, climate energy policy program

description: The wildland fire workforce faces numerous recruitment and retention challenges that are often amplified for groups historically underrepresented in the field. These barriers have not only contributed to insufficient workforce capacity, but have helped maintain a mostly homogenous workforce that has been reluctant to adapt its approach to managing wildfire despite the ever increasing need to forge a new relationship with fire. Building a workforce that can meet the needs of modern wildfire management will require comprehensive support for all fire personnel. Building a Robust and Representative Wildland Fire Mitigation and Management Workforce provides a roadmap to address the persistent cultural and structural challenges that have impeded the development of a more diverse, inclusive, and equitable fire management workforce. Recommendations include investing in inclusive opportunities for career development, addressing mental and physical health inequities, and strengthening workplace culture.
title: Continuous Carryover of Temporal Context Dissociates Response Bias from Perceptual Influence for Duration
Creators: name: Wiener, Martin
name: Thompson, James C.
name: Coslett, H. Branch
Publisher: name: Public Library of Science
Year: 2014
Subjects: subject: Vision
subject: Sensory perception
subject: Memory
subject: Psychometrics
subject: Human performance
subject: Sequence analysis
subject: Graphs
subject: Permutation

description: Recent experimental evidence suggests that the perception of temporal intervals is influenced by the temporal context in which they are presented. A longstanding example is the time-order-error, wherein the perception of two intervals relative to one another is influenced by the order in which they are presented. Here, we test whether the perception of temporal intervals in an absolute judgment task is influenced by the preceding temporal context. Human subjects participated in a temporal bisection task with no anchor durations (partition method). Intervals were demarcated by a Gaussian blob (visual condition) or burst of white noise (auditory condition) that persisted for one of seven logarithmically spaced sub-second intervals. Crucially, the order in which stimuli were presented was first-order counterbalanced, allowing us to measure the carryover effect of every successive combination of intervals. The results demonstrated a number of distinct findings. First, the perception of each interval was biased by the prior response, such that each interval was judged similarly to the preceding trial. Second, the perception of each interval was also influenced by the prior interval, such that perceived duration shifted away from the preceding interval. Additionally, the effect of decision bias was larger for visual intervals, whereas auditory intervals engendered greater perceptual carryover. We quantified these effects by designing a biologically-inspired computational model that measures noisy representations of time against an adaptive memory prior while simultaneously accounting for uncertainty, consistent with a Bayesian heuristic. We found that our model could account for all of the effects observed in human data. Additionally, our model could only accommodate both carryover effects when uncertainty and memory were calculated separately, suggesting separate neural representations for each. These findings demonstrate that time is susceptible to similar carryover effects as other basic stimulus attributes, and that the brain rapidly adapts to temporal context.
title: ANTA Magazine
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 1995
Subjects: subject: Theater
subject: Actors
subject: Broadway
subject: ANTA
subject: Detroit Drama Guild
subject: International Theatre Institute
subject: Campbell, C. Lawton
subject: Freedley, George
subject: Jones, Margo
subject: Draper, Margaret
subject: Butler, Bill
subject: Brandt, Alvin
subject: Gilder, Rosamond
subject: Jones, Kleine
subject: Simonson, Lee

description: Serial
Green Approach of Solvent- and Catalyst Free Synthesis of Bis(indolyl)methanes under Visible Light Irradiation
Creators: name: Hote, Baliram S.
name: Siddiqui, Tabbasum A. J.
name: Pisal, Parshuram M.
name: Mandawad, Gajanan G.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: An efficient procedure has been developed for the synthesis of bis(indolyl)methanes (3a-m) from condensation of indole (1) and various substituted aromatic aldehydes (2a-m) is described. The aromatic electrophilic substitution reactions of indole (1) with and various substituted aromatic aldehydes (2a-m) are achieved in solvent- and catalyst free condition using irradiation with 150W tungsten lamp (visible light irradiation). This methodology offers several advantages such as good yields, simple procedure, mild and environmentally benign conditions.
title: Town as Text: Harriet Jacobs and the Architecture of Literary and Historical Memory in Edenton, North Carolina
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2023
Subjects: subject: Harriet Jacobs
subject: Slavery
subject: African American literature
subject: Edenton
subject: North Carolina
subject: Civil War

description: In her Incidents in the Life of a Slave Girl, Harriet Jacobs’s relationships with and toward the constructed, physical spaces around her—plantation houses, hidden crawl spaces, jails, and churches—are intentionally obscured to create a patina of anonymity in her writing, yet the relational distance between and among locations nevertheless creates a map of an antebellum Edenton, North Carolina—the town of her enslavement—that can be read alongside her prose. Against this half-real, half-literary cartography sits presentday Edenton, where her work and life are signified more by their absence in the face of predominantly colonial and antebellum historical markers placed downtown and accompanying well-preserved architecture of Edenton’s elite. Jacobs’s use of both strategically abstract location markers, along with abolitionist rhetorical devices aimed at Northern White audiences, suggest that she is keenly conscious of her ability to shield Edenton by what she omits as much as what she shares, and thus asserts the power she has to literally name names. Her decision not to is a threat as much as an anonymizing tool for conceptualizing Edenton for abolitionist readers as an “everytown.” However, the Edenton outside of her text is not every town—its specific traits unique to the region both contributed to her escape and caused the climate that necessitated the departure. Jacobs further uses her Edenton as a stand-in for all other slaveholding communities, a metonymic tactic which urges the reader to scrutinize their own towns and, in doing so, to condemn the institution of chattel slavery.
title: Contentious Politics in Libya: A Study of the Initial Period of the 2011 Libyan Uprising
Creators: name: Talbot, Francis
Publisher: name: George Mason University
Year: 2017
Subjects: subject: Libya
subject: Contentious politics
subject: Social Movement Theory
subject: Revolution
subject: Scale-shifting process

description: This thesis describes the initial two weeks of the 2011 Libyan uprising. Through a detailed case study of this period, a narrative timeline is produced that includes significant events and descriptions of the actions taken by established and emerging political actors. Pulling from these descriptions, I consider whether this initial period of the Libyan uprising meets the criteria for an episode of contentious politics. Once establishing this, the thesis explores the scale shifting process commonly found in contentious politics and its applicability to the Libyan case. By identifying evidence of both brokerage and diffusion mechanisms as well as the emulation of a violent protest repertoire, I present the findings of the thesis. I concluded with recommendations on possible future research on Libya as an episode of political contention that could both deepen the understanding of the 2011 Libyan uprising and broaden the understanding of contentious politics in non-Western, non-democratic societies.
title: English Matters
Creators: name: (:Unkn) Unknown
Publisher: name: Roy Rosenzweig Center for History and New Media
Year: 2005
Subjects: subject: Digital humanities

description: The WARC file can be viewed using a web archiving program such as Conifer (https://conifer.rhizome.org). The ZIP contains a static version of the website.
description: English Matters was an online, multimedia journal for teachers and students of English questioning and creating new texts and pedagogies on the web. The site includes ten issues, featuring essays, exhibits, and performances. Hosted at englishmatters.gmu.edu.
title: Effects of Chimeric NMDA Receptor GluN2 Subunit Expression on Native NMDA Receptor Pools, Dendritic Morphology, and Synaptic Transmission in the Developing Hippocampus
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2022
Subjects: subject: Dendritic Morphology
subject: Development
subject: Electrophysiology
subject: GluN2
subject: Hippocampus
subject: NMDA Receptor
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Molecular biology
subject: Physiological psychology

description: The N-methyl-d-aspartate receptor (NMDAR) affects postnatal development of the rodent hippocampus: after the third postnatal week, NMDAR subunit composition shifts from GluN2B to GluN2A, changing both the calcium conductance and intracellular signaling of the NMDAR. It is unknown whether the change in kinetics or protein binding primarily actuate the neurobiological changes that permit mature cognition. Two transgenic mouse lines enable probing of this question: one expresses GluN2A channel domains coupled to the carboxy domain of GluN2B (ABc), while the other expresses GluN2B channel domains coupled to the carboxy domain of GluN2A (BAc). The effects of GluN2 domains on native NMDAR expression, neuron morphology, and synaptic function were examined. Western blotting and immunoprecipitation found that ~30% of native NMDARs are replaced by transgenic NMDARs without increasing total synaptic NMDARs. Dendritic imaging and tracing uncovered increased growth in ABc young adults. Field recordings revealed a higher EPSP amplitude in P22 – P24 ABc synapses. These results illustrate the role of GluN2 domains on late postnatal hippocampal development, providing insight into how GluN2 subunits affect the neurobiological underpinnings of mature learning and memory.
Supplementary document for Laguerre Gaussian mode holography - 6343146.pdf
Creators: name: Kong, Lingjun
name: zhang, rong
name: Zhang, Zhuo
name: Zhang, Jingfeng
name: Zhang, Xiangdong
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: OE-488116_RevisedManuscript_SD
A Multi-User Virtual Reality Social Connecting Space for People Living with Dementia and Their Support Persons: A Participatory Action Research Study
Creators: name: Flynn, Aisling
name: Koh, Wei Qi
name: Reilly, Gearóid
name: Brennan, Attracta
name: Redfern, Sam
name: Barry, Marguerite
name: Casey, Dympna
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Neuroscience
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Digital technologies such as virtual reality (VR) are increasingly designed and implemented to support people living with dementia who are at risk of loneliness and/or social isolation. Multi-user VR (MUVR), which involves simultaneous user engagement and a sense of being present together in VR, may promote and maintain social connectedness between people living with dementia and their support persons. This paper focuses on Phase 4 of a larger participatory action research (PAR) project, which aimed to explore the usability, acceptability and feasibility of a MUVR application and its potential to support the social connectedness of people living with dementia and their support persons. The study involved five people living with dementia and their five support persons, who trialed the application in their homes over two PAR cycles. The researcher gathered feedback through individual semi-structured interviews and observational field notes. Reflexive thematic analysis guided qualitative data analysis, and the findings suggested that MUVR is a usable, acceptable, and feasible application for this population. The findings also indicated that MUVR shows promise in promoting or maintaining social connectedness among people living with dementia and their support persons. Nonetheless, further refinement is necessary to enhance the usability, acceptability and feasibility of the MUVR application, and these areas of refinement are presented in this paper, through design recommendations for future work.
Enhancing Perceived Value in Human-Computer Interaction: The Mediating Role of User Participation and the Moderating Role of Task Complexity
Creators: name: Zheng, Hemingxi
name: Xiao, Daibo
name: Zhou, Jianxin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy

description: The study investigates the interplay of human-computer interaction (HCI) quality, user participation, and perceived value in technology interactions. The authors aim to elucidate the mediating role of user participation and the moderating effect of task complexity. Using structural equation modeling, we analyzed a diverse dataset of user feedback. The measurement and structural models are employed to determine the structural paths and predictive capability of the proposed model. Our findings indicate that user participation significantly mediates the impact of HCI quality on perceived value. Further, task complexity moderates these relationships, highlighting its role in enhancing or attenuating the perceived value of digital experiences. These findings provide insights for HCI design, emphasizing the need for user-centered systems that adapt to task complexity. Enhancing perceived value in technology interactions is essential, impacting user satisfaction, loyalty, and ultimately, the success of digital services.
Monitoring and Risk Assessment of Eight Polycyclic Aromatic Hydrocarbons (PAH8) in Daily Consumed Agricultural Products in South Korea
Creators: name: Kim, Wonjun
name: Choi, Jisu
name: Kang, Hwa Jeong
name: Lee, Jo-Won
name: Moon, Bokyung
name: Joo, Yong-Sung
name: Lee, Kwang-Won
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Agricultural products are consumed as major staple foods; these are the main factors responsible for polycyclic aromatic hydrocarbon (PAH) exposure to humans. We analyzed the concentrations of eight PAHs (PAH8) in commonly consumed 359 agricultural samples that are commonly consumed in Republic of Korea. These food samples were divided into four groups (fatty-solid, fatty-liquid, nonfatty-solid, and nonfatty-liquid) and eight different food categories (cereals, potatoes, pulse crops, seeds and nuts, vegetables, mushrooms, fruits, and regional tap water). The chronic daily intake and margin of exposure (MOE) were estimated based on daily consumption data and benzo[a]pyrene equivalents. In our total diet studies, the major contributor to the total PAH8 concentration (ΣPAH8) in agricultural samples was dried jujube (2.32 μg/kg), followed by griddled milk bread (1.25 μg/kg) and stir-fried black sesame (1.17 μg/kg). The integrated toxic equivalent concentrations based on BaP (ΣTEQbap; integrated toxic benzo[a]pyrene equivalent quantity) considering the relative toxicity, ranged from 0.12 and 1.6 μg/kg. The PAH8 risk assessment in agricultural products was expressed as the MOE value. The worst scenario (when Not Detected = Limit of Detection) showed the interpretation of the MOE result as a ‘possible concern’ to consume bread products (bread, rye bread, milk bread, and cornbread). The preceding experiments were carried out mainly on commercially processed foods and their raw foods. Unlike such routine testing, our total diet study-based monitoring is designed to monitor PAH8 levels in which agricultural products are analyzed after being processed as usual consumption.
Solvent-Free One-Pot Synthesis of Diverse Dihydropyrimidinones/Tetrahydropyrimidinones Using Biginelli Reaction Catalyzed by Fe3O4@C@OSO3H
Creators: name: Hatkehlouei, Seyedeh Fatemeh Taheri
name: Mirza, Behrooz
name: Soleimani-Amiri, Somayeh
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: One-pot synthesis of 3,4-dihydropyrimidinone/thione and 3,4,5,6-tetrahydropyrimidinone/thione derivatives was successfully performed in high yields through the reaction of aromatic aldehyde, β-dicarbonyl, urea/thiourea using Fe3O4@C@OSO3H nano-catalyst under solvent-free conditions at 80 °C. Fe3O4@C@OSO3H was introduced as an efficient magnetic nano-catalyst in Biginelli condensation with powerful reusability. The great yield of products, fast reaction time, simple work-up procedure, as well as usage of nontoxic, reusable, and easily recoverable catalyst with an external magnet was counted as advantages of the applied process. The magnetic nano-catalyst was removed after reaction completion and reused seven times at the same conditions without significant decay in catalyst activity. The magnetic nano-catalyst was synthesized through a simple and inexpensive two steps method and characterized by FT-IR, EDX, SEM, TEM, DLS, XRD, and VSM techniques.
Supplementary document for High‑Power Multi-Junction 905-nm Vertical Cavity Surface Emitting Laser with AlGaAsSb Electron Blocking Layer - 6343253.pdf
Creators: name: Zhao, Feiyun
name: Li, Yan
name: TANG, ZHITING
name: Ren, Aobo
name: Jiang, Wu
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Facile Synthesis of Polyfunctional Indole-Pyrido[2,3-d]Pyrimidine Hybrids Using Nickel-Incorporated Fluorapatite Encapsulated Iron Oxide Nanocatalyst and Study of Their Antibacterial Activities
Creators: name: Dastmard, Sahar
name: Mamaghani, Manouchehr
name: Farahnak, Lahya
name: Rassa, Mehdi
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Fe3O4@FAp@Ni was synthesized and has been used as a new and efficient recyclable magnetic nanocatalyst for the synthesis of polyfunctional indole-pyrido[2,3-d]pyrimidine hybrids. The Fe3O4@FAp@Ni was conveniently separated by an external magnet and could be reused at least six times without any appreciable change in catalytic activity. This novel protocol furnished the products in high to excellent yield (75–95%) and short reaction time. The antibacterial properties of the products were also evaluated and some of them exhibited promising activities.
Tetrazoloquinoline-1,2,3-Triazole Derivatives as Antimicrobial Agents: Synthesis, Biological Evaluation and Molecular Docking Study
Creators: name: Shaikh, Mubarak H.
name: Subhedar, Dnyaneshwar D.
name: Akolkar, Satish V.
name: Nagargoje, Amol A.
name: Khedkar, Vijay M.
name: Sarkar, Dhiman
name: Shingate, Bapurao B.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified

description: In search of new active molecules, a small focused library of tetrazoloquinoline-based 1,2,3-triazoles has been efficiently prepared via click chemistry approach. Several derivatives were found to be exhibiting promising antimicrobial and antioxidant activity characterized by their lower minimum inhibitory concentration values. All the synthesized compounds exhibited excellent antibacterial activity against Gram negative bacteria E. coli and F. devorans and antifungal activity against C. albicans and A. niger. Further, these compounds were tested for their antitubercular activity against dormant MTB H37Ra and dormant M. bovis BCG using XRMA assay protocol and showed no significant activity. Also, the synthesized compounds were found to have potential antioxidant activity with IC50 range = 12.48–50.20 μg/mL. Furthermore, to rationalize the observed biological activity data, the molecular docking study also been carried out against the active site of fungal C. albicans enzyme P450 cytochrome lanosterol 14α-demethylase, which revealed a significant correlation between the binding score and biological activity for these compounds. The results of the in vitro and in silico study suggest that the triazole-incorporated tetrazoloquinolines may possess the ideal structural requirements for further development of novel therapeutic agents.
Carboxymethyl Cellulose (CMC) as a Recyclable Green Catalyst Promoted Eco-Friendly Protocol for the Solvent-Free Synthesis of 1H-Pyrazolo[1,2-b]Phthalazine-5,10-Dione Derivatives
Creators: name: Mohamadpour, Farzaneh
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: An eco-safe synthetic route for convenient one-pot synthesizing 1H-pyrazolo[1,2-b] phthalazine-5,10-dione derivatives through Knoevenagel-Michael cyclocondensation is reported in carboxymethyl cellulose (CMC) based on green chemistry principles. The prominent benefits include use of recyclable green catalyst, commercially accessible inexpensive starting materials, operational simplicity, non-hazardous reaction circumstances, high atom-economy, solvent-free, short reaction times and high yields.
Enhancement of air oxidation and hot corrosion resistance of high-temperature municipal waste incinerators and coal-fired power plants metallic walls: a review
Creators: name: Roshith, P
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: The operating effectiveness of Indian boilers is significantly compromised by the severe risk constituted by the early breakdown malfunctioning of boiler tubes, particularly in those powered by coal. The principal cause of stoppage and substantial financial deprivation in coal-fired thermal energy plant boilers is erosion and hot corrosion. This article summarizes the combined findings of multiple scientists who have focused on addressing the issue of degradation at elevated temperatures in boiler tubes, particularly in the circumstances of boilers in Bharat, both in real-world and artificial conditions. The findings aid the scientists in choosing the right combination of coating substances and variables for specific boiler steel and coating techniques. This selection aims to enhance the lifespan of boiler tubes effectively. Therefore, the goal is to reduce any undesirable harm to boiler tubes caused by hot corrosion. The discourse concerning potential industrial utilizations and practical applications, a more lucid juxtaposition of the advantages and disadvantages of various coating materials, and the hurdles encountered along with recommendations for forthcoming endeavors, notably regarding novel materials and inventive coating methodologies, have been incorporated.
Efficient recovery of phosphorus and iron from the lithium extraction slag by the leaching precipitation method
Creators: name: Tu, Tao
name: Yu, Xiuyuan
name: Liu, Qingsheng
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences

description: The key to recovering waste LiFePO4(LFP) is the recovery of lithium; however, the effective and synchronous recovery of phosphorus and iron resources still needs to be achieved. In this paper, a new process was proposed for recovering phosphorus and iron from the lithium extraction slag (LES) of waste LFP by the leaching and precipitation method. Based on the thermodynamic analysis of Fe3+ and PO43− and XRD results, the experimental conditions were discussed in detail. There were three stable regions when the solution pH value was from 0 to 5, no precipitation at pH = 0–0.664, stable existence of FePO4(s) at pH = 0.664–1.203, coexistence of FePO4(s), and AlPO4(s) when pH > 1.203, respectively. The leaching solution of LES by hydrochloric acid could prepare FePO4·2H2O under the following optimal conditions: 95°C, pH 1.5, feeding speed 1.5 mL min−1. The synthesised iron phosphate was pure and distributed in flakes. Additionally, the discharge capacity of the LiFePO4/C prepared by the regenerative FePO4·2H2O was 147 mAh g−1 at 0.1 C and showed good cycle stability at 1 C. The method not only recovers FePO4 from the LES but also shows simple operation and high efficiency.
title: Improving remote sensing flood assessment using volunteered geographical data
Creators: name: Schnebele, E.
name: Cervone, G.
Publisher: name: Copernicus Publications
Year: 2013
Subjects: subject: Remote sensing
subject: Volunteered ground data
subject: Statistical flood model
subject: Flood hazard maps

description: A new methodology for the generation of flood hazard maps is presented fusing remote sensing and volunteered geographical data. Water pixels are identified utilizing a machine learning classification of two Landsat remote sensing scenes, acquired before and during the flooding event as well as a digital elevation model paired with river gage data. A statistical model computes the probability of flooded areas as a function of the number of adjacent pixels classified as water. Volunteered data obtained through Google news, videos and photos are added to modify the contour regions. It is shown that even a small amount of volunteered ground data can dramatically improve results.
title: Exploring the Concepts of “Homeland”, “Exile” and “Return” in the Palestinian Poetry through the Work of Mahmoud Darwish
Creators: name: Asli, Chadi
Publisher: name: George Mason University
Year: 2017
Subjects: subject: Palestinian poetry
subject: Homeland
subject: Exile
subject: Return
subject: Mahmoud Darwish

description: This thesis studies the Palestinian discourse on exile and return through the exploration of Palestinian poetry. Special attention will be given to the work of Mahmoud Darwish, a leading figure of Palestinian poetry. To this end, different pieces of literature concerning theories on social identity and collective memory mechanisms were chosen and reviewed. The analysis was divided into four different sections. Each section corresponds to a theme present and typical of Palestinian poetry. The systematic exploration of these themes in Palestinian poetry informs us on the Palestinian narrative about exile and the return. The themes studied are bloodlines, love, nature and mythology. Palestinian poets have used poetry as a strong communicative tool to narrate their experiences and feelings, whether personal or political. This was a good enough reason for me to choose the study of Mahmoud Darwish’s poetry works as study examples.
In Vitro and In Silico Studies of Quinoline-2-Carbaldehyde Hydrazone Derivatives as Potent Antimicrobial Agents
Creators: name: Celik, Ismail
name: Erol, Meryem
name: Puskullu, Mustafa Orhan
name: Uzunhisarcikli, Ebru
name: Ince, Ufuk
name: Kuyucuklu, Gulcan
name: Suzen, Sibel
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 60506 Virology

description: We previously synthesized a series of quinoline-2-carbaldehyde hydrazone derivatives and evaluated their antioxidant activities. In this study, the antimicrobial activities of these quinoline-2-carbaldehyde hydrazone derivatives were evaluated antimicrobial activity by the microdilution method, and there cytotoxic effect was investigated in MCF-7 and A549 cells by MTT assay. When the activity results were examined, although the antimicrobial activity of quinoline derivatives were equal or better than standard drugs in general, compound 4 (2 µg/mL) and 8 (1 µg/mL) against E. faecalis and 5 (8 µg/mL) against P. aeruginosa are the most effective derivatives of the series. Besides, disk diffusion test was applied to these three compounds, and significant zone formation was observed at 8 (7 mm) compared to vancomycin (9 mm). Compounds showed no antiproliferative in A549 and MCF-7 cell lines, and compound 4, 5, and 8, which showed the most effective antimicrobial activity, were examined in healthy cells (Beas-2b) and no effect on cell viability was found. To understand the mechanism of this action of these compounds against E. faecalis, molecular docking studies were performed on 15 different proteins, and it was concluded that the compounds interacted with FabH and not enough with other protein structures. The theoretical ADME profiles of compounds comply with Lipinski and other limiting rules. Also, some theoretical quantum parameters (HOMO-LUMO) of compounds, and both MEP analysis and geometric optimization analysis of 8 were calculated with 6–311 G (d,p) base set and DFT/B3LYP theory, and the results were shown.
title: A Proteomic Profile of Imidacloprid and its Active Metabolites Desnitro-Imidacloprid and Imidacloprid-Olefin in Human Neural Cells
Creators: name: Girish Kumar, Sreehari
Publisher: name: George Mason University
Year: 2023
Subjects: subject: Mass Spectrometry Analysis
subject: Imidacloprid
subject: Imidacloprid-Olefin
subject: Neonicotinoids
subject: Proteomics
subject: Des-nitro Imidacloprid

description: Neonicotinoids are a popular class of pesticides around the world and have been shown to bind both insect and mammalian nicotinic acetylcholine receptors (nAChRs). Imidacloprid (IMI), is amongst the most commonly used neonicotinoids in agriculture and domestic, non-industrial, applications but shows strong toxic effects in many organisms. In addition, the potential for toxicity from its two main metabolites desnitroimidacloprid (DN-IMI) and imidacloprid-olefin (IMI-olefin), are not yet defined despite recent evidence that they can bind to the mammalian nAChR. In this study, we used Lund Human Mesencephalic (LUHMES) cells, as a human cell line model of dopaminergic neurons to test the effects of IMI and its metabolites. Cells were treated with 50μM IMI, DN-IMI, and IMI-olefin for 48 hours, and then examined for proteomic change using liquid-chromatography electrospray ionization mass spectrometry (LC-ESI MS/MS). Bioinformatic analysis using Gene Ontology (GO) and enrichment analysis were performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG), Reactome, and WikiPathways databases. Our results provide novel insight into convergent as well as differential molecular effects by IMI, DN-IMI, and IMI-olefin in neural cells. These studies begin to explore pathways of neonicotinoid neurotoxicity leading to neuro disease in exposed individuals.
Supplementary document for 3D full-wave multi-scattering forward solver for coherent microscopes - 6343684.pdf
Creators: name: Qin, Yingying
name: Butola, Ankit
name: Agarwal, Krishna
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1: total field, generalization to QPM, focused illumination, dark-field microscopy
The Microwave Assisted and Efficient Synthesis of 2-Substituted Benzimidazole Mono-Condensation of O-Phenylenediamines and Aldehyde
Creators: name: Tayade, Amit P.
name: Pawar, Ramkrushna P.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Synthesis of 2-substituted benzimidazole derivatives using reactants aldehyde, o-phenylenediamine, and sodium hypophosphite as a catalyst using microwave irradiation. An efficient and green synthesis carried out using sodium hypophosphite gives high yield in shorts reaction time. This route provides key advantages such as high yield, clean, easy work-up, readily available catalyst, and good yield. Compared with the conventional method, microwave irradiation process has more advantages.
title: Early Socialization and Later Aggression: A Multi-Informant Longitudinal Analysis of Parent and Peer Relationships in Early Childhood and Aggression in Grade School
Creators: name: Mize, Jerry L
Publisher: name: George Mason University
Year: 2018
Subjects: subject: Aggression
subject: Maternal relationships
subject: Peer relationships
subject: Childhood
subject: Adolescence
subject: Longitudinal

description: Although the childhood aggression literature is well developed, there is relatively little research examining longitudinal relations between early childhood parenting and peer interaction and later aggressive behavior in children. Relationships with parents affect how future relationships are approached, and receiving sensitivity from and having a secure relationship with one’s parents are related to less child aggression. Additionally, peer relationships contribute to the development of aggression. The current study examines how characteristics of parental quality (maternal sensitivity, conflict, and closeness) and interactions with peers (prosocial, aggression, and positive and negative contributions to play) at 54-months are associated with children’s aggressive behavior, as reported by multiple informants, in 3rd grade through 6th grade (N = 1,364; 52.4% female; 85.4% White). Data came from the SECCYD, and I tested these associations with structural equation modeling using Mplus version 6. Maternal, teacher, and self reports of aggressive behavior in grades 3-6 were examined. In the maternal report model, I report stability in aggression behaviors overtime and that maternal relationships in early childhood are related to general and relational aggression, but generally unrelated to changes in child general and relational aggression across grades 3-6. I also did not find much of a relation between friendships in early childhood and later aggression. Further, only the maternal report yielded significant findings. I conclude that maternal relationships could be predictive of maternal views of their children’s initial aggressive behavior, both relationally and in general, but not predictive of changes in aggression. Overall, these findings suggest that prevention and intervention efforts should be focused prior to third grade.