cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of comorbidity assessed by the Charlson Comorbidity Index on the length of stay, costs, and mortality among colorectal cancer patients undergoing colorectal surgery
Creators: name: Zhang, Xuexue
name: Wang, Xujie
name: Wang, Miaoran
name: Gu, Jiyu
name: Guo, Huijun
name: Yang, Yufei
name: Liu, Jian
name: Li, Qiuyan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Charlson Comorbidity Index (CCI) is a good predictor for hospitalization cost and mortality among patients with chronic disease. However, the impact of CCI on patients after colorectal cancer surgery is unclear. This study aims to investigate the influence of comorbidity assessed by CCI on length of stay, hospitalization costs, and in-hospital mortality in patients with colorectal cancer (CRC) who underwent surgical resection. This historical cohort study collected 10,271 adult inpatients for CRC undergoing resection surgery in 33 tertiary hospitals between January 2018 and December 2019. All patients were categorized by the CCI score into four classes: 0, 1,2, and ≥3. Linear regression was used for outcome indicators as continuous variables and logical regression for categorical variables. EmpowerStats software and R were used for data analysis. Of all 10,271 CRC patients, 51.72% had at least one comorbidity. Prevalence of metastatic solid tumor (19.68%, except colorectal cancer) and diabetes without complication (15.01%) were the major comorbidities. The highest average cost of hospitalization (86,761.88 CNY), length of stay (18.13 days), and in-hospital mortality (0.89%) were observed in patients with CCI score ≥3 compared to lower CCI scores (p < .001). Multivariate regression analysis showed that the CCI score was associated with hospitalization costs (β, 7340.46 [95% confidence interval (CI) (5710.06–8970.86)], p < .001), length of stay (β, 1.91[95%CI (1.52–2.30)], p < .001), and in-hospital mortality(odds ratio (OR),16.83[95%CI (2.23–126.88)], p = .0062) after adjusted basic clinical characteristics, especially when CCI score ≥3. Notably, the most specific complication associated with hospitalization costs and length of stay was metastatic solid tumor, while the most notable mortality-specific comorbidity was moderate or severe renal disease. The research work has discovered a strong link between CCI and clinical plus economic outcomes in patients with CRC who underwent surgical resection.
title: Spatio-Temporal Associations Between Deforestation and Malaria Incidence in Lao PDR
Creators: name: Rerolle, Francois
name: Dantzer, Emily
name: Lover, Andrew A.
name: Marshall, John M.
name: Hongvanthong, Bouasy
name: Sturrock, Hugh J. W.
name: Bennett, Adam
Publisher: name: University of Massachusetts Amherst
Year: 2021
Subjects: subject: RESOLUTION GLOBAL-MAPS
subject: FOREST MALARIA
subject: FALCIPARUM-MALARIA
subject: CENTRAL VIETNAM
subject: RISK-FACTORS
subject: ELIMINATION
subject: POPULATION
subject: TRANSMISSION
subject: PATTERNS
subject: VECTOR
subject: Biology

description: As countries in the Greater Mekong Sub-region (GMS) increasingly focus their malaria control and elimination efforts on reducing forest-related transmission, greater understanding of the relationship between deforestation and malaria incidence will be essential for programs to assess and meet their 2030 elimination goals. Leveraging village-level health facility surveillance data and forest cover data in a spatio-temporal modeling framework, we found evidence that deforestation is associated with short-term increases, but long-term decreases confirmed malaria case incidence in Lao People's Democratic Republic (Lao PDR). We identified strong associations with deforestation measured within 30 km of villages but not with deforestation in the near (10 km) and immediate (1 km) vicinity. Results appear driven by deforestation in densely forested areas and were more pronounced for infections with Plasmodium falciparum (P. falciparum) than for Plasmodium vivax (P. vivax). These findings highlight the influence of forest activities on malaria transmission in the GMS.
Persuasive Technology in Reducing Prolonged Sedentary Behavior at Work: A Systematic Review
Creators: name: Wang, Yunlong
name: Wu, Lingdan
name: Lange, Jan-Philipp
name: Fadhil, Ahmed
name: Reiterer, Harald
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences
subject: J.3; K.6.1

description: Prolonged sedentary behavior is prevalent among office workers and has been found to be detrimental to health. Preventing and reducing prolonged sedentary behavior require interventions, and persuasive technology is expected to make a contribution in this domain. In this paper, we use the framework of persuasive system design (PSD) principles to investigate the utilization and effectiveness of persuasive technology in intervention studies at reducing sedentary behavior at work. This systematic review reveals that reminders are the most frequently used PSD principle. The analysis on reminders shows that hourly PC reminders alone have no significant effect on reducing sedentary behavior at work, while coupling with education or other informative session seems to be promising. Details of deployed persuasive technology with behavioral theories and user experience evaluation are expected to be reported explicitly in the future intervention studies.
Additional file 1: of Hybridity has a greater effect than paternal genome dosage on heterosis in sugar beet (Beta vulgaris)
Creators: name: Hallahan, Brendan
name: Fernandez-Tendero, Eva
name: Fort, Antoine
name: Ryder, Peter
name: Dupouy, Gilles
name: Deletre, Marc
name: Curley, Edna
name: Brychkova, Galina
name: Schulz, Britta
name: Spillane, Charles
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 60506 Virology

description: Detailed methods of genotyping-by-sequencing analysis. The steps taken for library preparation, high-throughput DNA sequencing, bioinformatic analysis of sequencing data, and software used are explained herein. (DOCX 370 kb).
New insight into the low-energy $^9$He spectrum
Creators: name: Golovkov, M. S.
name: Grigorenko, L. V.
name: Fomichev, A. S.
name: Gorshkov, A. V.
name: Gorshkov, V. A.
name: Krupko, S. A.
name: Oganessian, Yu. Ts.
name: Rodin, A. M.
name: Sidorchuk, S. I.
name: Slepnev, R. S.
name: Stepantsov, S. V.
name: Ter-Akopian, G. M.
name: Wolski, R.
name: Korsheninnikov, A. A.
name: Nikolskii, E. Yu.
name: Kuzmin, V. A.
name: Novatskii, B. G.
name: Stepanov, D. N.
name: Fortier, S.
name: Roussel-Chomaz, P.
name: Mittig, W.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The spectrum of $^9$He was studied by means of the $^8$He($d$,$p$)$^9$He reaction at a lab energy of 25 MeV/n and small center of mass (c.m.) angles. Energy and angular correlations were obtained for the $^9$He decay products by complete kinematical reconstruction. The data do not show narrow states at $\sim $1.3 and $\sim $2.4 MeV reported before for $^9$He. The lowest resonant state of $^9$He is found at about 2 MeV with a width of $\sim $2 MeV and is identified as $1/2^-$. The observed angular correlation pattern is uniquely explained by the interference of the $1/2^-$ resonance with a virtual state $1/2^+$ (limit on the scattering length is obtained as $a > -20$ fm), and with the $5/2^+$ resonance at energy $\geq 4.2$ MeV.
description: 5 pages, 4 figures, 2 tables
title: Trajectoire
Creators: name: Mouton, Léa
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Hmong noir
subject: hmn

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Additional file 1: of Doxorubicin-induced cardiotoxicity is suppressed by estrous-staged treatment and exogenous 17β-estradiol in female tumor-bearing spontaneously hypertensive rats
Creators: name: Kaytee Pokrzywinski
name: Biel, Thomas
name: Rosen, Elliot
name: Bonanno, Julia
name: Baikuntha Aryal
name: Mascia, Francesca
name: Delaram Moshkelani
name: Mog, Steven
name: V. Ashutosh Rao
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer

description: Study design and supporting material. Figure S1. SHR study design to evaluate estrous cycle effects on DOX-induced cardiotoxicity. Figure S2. OvaSHR study design to evaluate the effects of exogenous hormone supplementation and Dox-induced cardiotoxicity. Figure S3. DRZ does not affect estrous cycle in SHRs. Figure S4. Uterine width changes in SHRs. Figure S5. DRZ does not affect the weight, tumor growth or uterine width in SHRs. Figure S6. DRZ alone does not cause cardiotoxicity in SHRs. Figure S7. Uterine width changes in ovaSHRs administered exogenous E2 and P4. Figure S8. Weight and tumor volume changes in hormone-implanted ovaSHRs. Figure S9. Hormone receptor expression in MCF-7 and SST-2 cell lines. (PDF 1172 kb)
Precision Learning: Towards Use of Known Operators in Neural Networks
Creators: name: Maier, Andreas
name: Schebesch, Frank
name: Syben, Christopher
name: Würfl, Tobias
name: Steidl, Stefan
name: Choi, Jang-Hwan
name: Fahrig, Rebecca
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this paper, we consider the use of prior knowledge within neural networks. In particular, we investigate the effect of a known transform within the mapping from input data space to the output domain. We demonstrate that use of known transforms is able to change maximal error bounds. In order to explore the effect further, we consider the problem of X-ray material decomposition as an example to incorporate additional prior knowledge. We demonstrate that inclusion of a non-linear function known from the physical properties of the system is able to reduce prediction errors therewith improving prediction quality from SSIM values of 0.54 to 0.88. This approach is applicable to a wide set of applications in physics and signal processing that provide prior knowledge on such transforms. Also maximal error estimation and network understanding could be facilitated within the context of precision learning.
description: accepted on ICPR 2018
Bisabolane-type sesquiterpenoids and bacillibactin from the marine-derived fungus Aspergillus sydowii SCSIO 41041 and their enzyme inhibiting activity
Creators: name: Song, Ying-Ying
name: Liu, Qing-Xia
name: Pang, Xiao-Yan
name: Chen, Zhi-Yun
name: Huang, Hong-Hui
name: Wang, Jun-Feng
name: Liu, Yong-Hong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Virology

description: Twelve compounds, including eleven bisabolane-type sesquiterpenoids (1 − 11), and one bacillibactin (12) were identified from marine-derived fungus Aspergillus sydowii SCSIO 41041 isolated from Creseis acicula. The chemical structures were elucidated by the basis of spectroscopic evidences, including HRESIMS, NMR and optical rotation. Biologically, all compounds were evaluated for their acetyl cholin-esterase (AChE) enzyme, pancreatic lipase (PL) enzyme, neuraminidase (NA) and phosphodiesterase 4 (PDE4) inhibitory activities. Compound 12 displayed significant inhibitory activity against neuraminidase (NA) with an IC50 value of 24.0 μM, which was equivalent to the positive drug oseltamivir phosphate (IC50 value of 20.0 μM). And the NA inhibitory activity was confirmed by molecular docking analysis.
Nonet Classification of Scalar/Isoscalar Resonances below 1900 MeV: the Existence of an Extra Scalar State in the Region 1200-1600 MeV
Creators: name: Anisovich, V. V.
name: Prokoshkin, Yu. D.
name: Sarantsev, A. V.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A classification of the $IJ^{PC}=00^{++}$ mesons is performed on the basis of the K-matrix analysis of meson spectra in the reactions: (i) GAMS data on $πp\to π^0π^0 n$, $ηηn$, $ηη' n$; (ii) Crystal Barrel data on $p\bar p~(at~rest)\to π^0π^0π^0$, $π^0π^0η$, $π^0ηη$; (iii) CERN-Münich data on $πp\to π^+π^- n$; (iiii) BNL data on $πN\to K\bar K N$. The analysis points to the existence of four comparatively narrow scalar resonances which correspond to the following poles of the scattering amplitude (in MeV): $(1015\pm 15)- i(43\pm 8)$, $(1300\pm 20)-i(120\pm 20)$, $(1499\pm 8)-i(65\pm 10)$ and $(1780\pm 30)-i(125\pm 70)$. The scattering amplitude also has a fifth pole $f_0(1530^{+90}_{-250})$ at the complex mass $(1530^{+90}_{-250}) - i(560\pm 140)$. The masses of the K-matrix poles (bare states) are at $720\pm 100$ MeV, $1230\pm 50$ MeV, $1260\pm 30$ MeV, $1600\pm 50$ MeV and $1810\pm 30$ MeV. The quark content of the bare states is analyzed using the values of their couplings to the $ππ$, $K\bar K$, $ηη$ and $ηη'$. It is shown that one of the bare states in the mass region 1200-1600 MeV is superfluous for the $q\bar q$ classification and should be considered as the lightest glueball.
description: LaTex 26 pages and 8 figures
Arctium lappa L. root polysaccharides ameliorate CCl4-induced acute liver injury by suppressing oxidative stress, inflammation and apoptosis
Creators: name: Xiang, Wen
name: Wei, Jiayi
name: Lv, Lifei
name: Yu, Xinghui
name: Xie, Yan
name: Zhang, Li
name: Lu, Naiyan
name: Jiang, Wentao
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: In this study, water-soluble polysaccharides purified from burdock root were used to intervene in carbon tetrachloride (CCl4)-induced acute liver injury (ALI) of BRL3A hepatocytes and rats. Our results indicated that CCl4 significantly inhibited hepatocyte viability and upregulated the expression of reactive oxygen species (ROS), malondialdehyde (MDA), pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6), and the pro-apoptotic protein Bax. However, Arctium lappa L. root polysaccharides (ALP) could effectively ameliorate liver function and histopathology, oxidative stress, and inflammatory markers. In addition, ALP reduced the expression of apoptotic markers and promoted the proliferation of damaged hepatocytes. In conclusion, ALP possesses a hepatoprotective effect mediated by attenuating oxidative damage, inflammation and apoptosis in ALI.
Critical Lines in Gravitational Lenses and the Determination of Cosmological Parameters
Creators: name: Asada, Hideki
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigate the cosmological test recently proposed by B. Fort, Y. Mellier and M. Dantel-Fort (FMD), where the observed location of the critical line in gravitational lensing is used to determine the cosmological parameters, $Ω$ and $λ$. Applying this method to the cluster of galaxies Cl0024+1654, FMD obtained a constraint on the cosmological constant, $λ> 0.6$, assuming the spatially flat universe. It plays a crucial role in this method that the angular diameter distance-redshift relation depends on the cosmological models through the cosmological parameters. First, using the angular diameter distance in the Friedmann-Lemaitre- Robertson-Walker universe, we show that one can hardly determine $Ω$ by this method without the assumption of the spatially flat universe. We also investigate the effect of inhomogeneities of the universe by using the Dyer-Roeder angular diameter distance. It is shown that the effect of inhomogeneities can become too large to be ignored, particularly for a high density universe. As a result, this method cannot be taken as a clear cosmological test to determine $Ω$ and $λ$, though it may provide a bound on $Ω$ and $λ$. Moreover, we mention the uncertainty of the determination of the velocity dispersion, which is regarded as one of the most serious problems in this test.
description: 16 pages, LaTeX(aaspp4), 11 postscript figures included; submitted to The Astrophysical Journal
Structurally diverse indole alkaloids with cytotoxicity from Lonicera Japonica-associated endophytic fungus Penicillium ochrochloron YT2022-65
Creators: name: Liu, Xingjie
name: Li, Ruonan
name: Zhou, Xiaofei
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Natural products, especially fungal secondary metabolites, have been served as valuable sources of drug leads in pharmaceutical industry. Medicinal plants-associated endophytic fungi possess a well-developed secondary metabolism. In this study, chemical investigation on Penicillium ochrochloron YT2022-65, an endophytic fungus associated with Lonicera Japonica, led to the isolation of six structurally diversified indole alkaloids, including a new one, namely peniochroloid A (1), as well as five previously reported alkaloids, flavonoid B (2), brocaeloid C (3), isoroquefortine C (4), roquefortine C (5), and dihydrocarneamide A (6). Their structures, including the absolute configuration of 1, were determined by a combined analysis of HRESIMS, NMR spectroscopic data, and calculation of the optical rotation. Their cytotoxicity against A549, HepG2, MCF-7, and THP-1 cell lines were evaluated in vitro. The new compound 1 was found to possess considerable cytotoxicity against MCF-7 and THP-1 cell lines with IC50 values of 10.2 and 11.0 μM, respectively.
Study of the production mechanism of the eta meson by means of analysing power measurements
Creators: name: Czyzykiewicz, R.
name: Moskal, P.
name: Adam, H. -H.
name: Budzanowski, A.
name: Czerwinski, E.
name: Gil, D.
name: Grzonka, D.
name: Janusz, M.
name: Jarczyk, L.
name: Kamys, B.
name: Khoukaz, A.
name: Klaja, P.
name: Lorentz, B.
name: Majewski, J.
name: Oelert, W.
name: Piskor-Ignatowicz, C.
name: Przerwa, J.
name: Ritman, J.
name: Rohdjess, H.
name: Rozek, T.
name: Sefzick, T.
name: Siemaszko, M.
name: Smyrski, J.
name: Taeschner, A.
name: Ulbrich, K.
name: Winter, P.
name: Wolke, M.
name: Wuestner, P.
name: Zipper, W.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Information about the production mechanism of the eta meson in proton-proton collisions can be inferred by confronting the experimental studies on the analysing power for the p(pol)p --> pp eta reaction with the theoretical predictions of this observable. Results show that the predictions of pure pseudoscalar- or vector meson exchange model are insufficient to describe the analysing powers.
description: 4 pages, 4 figures, Presented at MESON 2006: 9th International Workshop on Meson Production, Properties and Interactions, Cracow, Poland, 9-13 Jun 2006
Additional file 1: of Schistosomiasis in immigrants, refugees and travellers in an Italian referral centre for tropical diseases
Creators: name: Marchese, Valentina
name: Beltrame, Anna
name: Angheben, Andrea
name: Monteiro, Geraldo
name: Giorli, Giovanni
name: Perandin, Francesca
name: Buonfrate, Dora
name: Bisoffi, Zeno
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Multilingual abstracts in the five official working languages of the United Nations. (PDF 537 kb)
Additional file 1 of Rabbit haemorrhagic disease virus Lagovirus europaeus/GI.1d strain: genome sequencing, in vivo virus replication kinetics, and viral dose effect
Creators: name: Droillard, Clément
name: Lemaitre, Evelyne
name: Amelot, Michel
name: Blanchard, Yannick
name: Keita, Alassane
name: Eterradossi, Nicolas
name: Le Gall-Reculé, Ghislaine
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1. List of primers used to amplify and/or to sequence the GI.1d/00–21 complete coding sequence.
Additional file 9 of Cancer-associated fibroblast infiltration in gastric cancer: the discrepancy in subtypes pathways and immunosuppression
Creators: name: Liu, Xu
name: Yao, Li
name: Qu, Jingkun
name: Liu, Lin
name: Lu, Ning
name: Wang, Jiansheng
name: Zhang, Jia
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 9: Fig. 5 immuno-suppressive modulators expression in TCGA cohort.
C21 steroidal glycosides from the root bark of Periploca sepium and their NO production inhibitory and cytotoxic activity
Creators: name: Shu, Zhi-Heng
name: Chen, Miao
name: Li, Yao
name: Fan, Cai-Lian
name: Chen, Wei-Wu
name: Xin-Sheng, Yao
name: Dai, Yi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: A series of C21 steroidal glycosides were isolated from the root bark of Periploca sepium, including a new compound, perisepiumoside A1 (1), and six known compounds (2-7). Their structures were elucidated by analysis of HR-ESI-MS, and 1D and 2D NMR spectroscopic data. All these compounds were tested for their NO production inhibitory activity in LPS-stimulated RAW 264.7 cells. Results showed that these C21 steroidal glycosides could remarkably inhibit NO production, particularly 1 and 2 with IC50 values of 30.81 ± 0.18 μM and 44.39 ± 0.21 μM, respectively. In addition, the cytotoxicity of these compounds was measured on A549, MCF-7, and HeLa cancer cell lines. Among them, compounds 1 and 7 displayed cytotoxicity against the A549 cell line with IC50 values of 28.41 ± 0.12 μM and 39.06 ± 0.05 μM, respectively.
Jets and accretion processes in Active Galactic Nuclei: further clues
Creators: name: Celotti, Annalisa
name: Padovani, Paolo
name: Ghisellini, Gabriele
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present evidence in favour of a link between the luminosity radiatively dissipated in the central engine of radio-loud Active Galactic Nuclei and the kinetic power in their jets. This piece of evidence is based on the relation we find between the luminosity in broad emission lines and the kinetic power in pc-scale radio jets, for a sample of radio-loud quasars for which suitable data are available in the literature. We find that the ionizing luminosity and the kinetic one are of the same order of magnitude, suggesting that the processes responsible for them are somehow related. A strong magnetic field in equipartition with the radiation field could be responsible for regulating both processes. BL Lac objects seem to follow a similar behaviour, but with comparatively fainter broad line emission.
description: 8 pages Latex file, 2 Postscript tables, 3 Postscript figures; MNRAS, in press
Dynamic quantum kagome ice
Creators: name: Lhotel, E.
name: Petit, S.
name: Hatnean, M. Ciomaga
name: Ollivier, J.
name: Mutka, H.
name: Ressouche, E.
name: Lees, M. R.
name: Balakrishnan, G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The search for two dimensional quantum spin liquids, exotic magnetic states with an entangled ground state remaining disordered down to zero temperature, has been a great challenge in frustrated magnetism during the last decades. Recently, fractionalized excitations, called spinons, emerging from these states, have been evidenced in kagome and triangular antiferromagnets. In contrast, quantum ferromagnetic spin liquids in two dimensions, namely quantum kagome ices, have been less investigated, yet their classical counterparts exhibit amazing properties, magnetic monopole crystals as well as magnetic fragmentation. Here we show that, by applying a magnetic field on the pyrochlore oxide Nd$_2$Zr$_2$O$_7$, which has been shown to develop three dimensional quantum magnetic fragmentation in zero field, we are able to reduce the dimension of the system and to create a dynamic kagome ice state. Our results open the way to the observation of the quantum kagome ice state which was recently investigated theoretically.
description: 7 pages, 4 figures + Supplementary information
Naturally occurring organosulfur compounds effectively inhibits PCSK-9 activity and restrict PCSK-9-LDL-receptor interaction via in-silico and in-vitro approach
Creators: name: Ahmad, Parvej
name: Alvi, Sahir S.
name: Waiz, Mohd
name: Khan, Mohd Shahnawaz
name: Ahmad, Saheem
name: Khan, M. Salman
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: The present study intended to divulge the potential role of garlic-derived organosulfur compounds (OSCs) in targeting PCSK-9 and averting its interaction with the EGF-A portion of LDL-R via in-vitro and in-silico analysis. Our in-silico screening data showed that 3-(Propylsulfinyl)-L-alanine (PSA), S-Ethyl-L-cysteine (SEC), alliin, and S-Allyl-L-cysteine (SAC) exhibited higher binding energy (−7.05, −7.00, −6.65, and −6.31 Kcal/mol, respectively) against PCSK-9, among other selected OSCs. Further, the protein-protein interaction study of PCSK-9-OSCs-complex with EGF-A demonstrated a similar binding pattern with E-total values ranging from −430.01 to −405.6 Kcal/mol. These results were further validated via in-vitro analysis which showed that SEC, SAC, and diallyl trisulphide (DAT) exhibited the lowest IC50 values of 4.70, 5.26, and 5.29 µg/mL, respectively. In conclusion, the presented data illustrated that SEC, SAC, and DAT were the best inhibitors of PCSK-9 activity and may have the potential to improve the LDL-R function and lower the circulatory LDL-C level.
Additional file 1: of MMP-3 in the peripheral serum as a biomarker of knee osteoarthritis, 40Â years after open total knee meniscectomy
Creators: name: Pengas, Ioannis
name: Eldridge, Suzanne
name: Aggelos Assiotis
name: McNicholas, Michael
name: Joao Mendes
name: Laver, Lior
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: Plant Biology

description: (R plots) & Addendum. (DOC 164 kb)
title: Characteristics of HIV Seroconverters in the Setting of Universal Test and Treat: Results From the SEARCH Trial in Rural Uganda and Kenya
Creators: name: Nyabuti, Marilyn N.
name: Petersen, Maya L.
name: Bukusi, Elizabeth A.
name: Kamya, Moses R.
name: Mwangwa, Florence
name: Kabami, Jane
name: Sang, Norton
name: Charlebois, Edwin D.
name: Balzer, Laura B.
Publisher: name: University of Massachusetts Amherst
Year: 2021
Subjects: subject: RISK BEHAVIOR
subject: AGE-DISPARATE
subject: AFRICA
subject: WOMEN
subject: INFECTION
subject: MEN
subject: SEX
subject: Other Medicine and Health Sciences

description: Background Additional progress towards HIV epidemic control requires understanding who remains at risk of HIV infection in the context of high uptake of universal testing and treatment (UTT). We sought to characterize seroconverters and risk factors in the SEARCH UTT trial (NCT01864603), which achieved high uptake of universal HIV testing and ART coverage in 32 communities of adults (>= 15 years) in rural Uganda and Kenya. Methods In a pooled cohort of 117,114 individuals with baseline HIV negative test results, we described those who seroconverted within 3 years, calculated gender-specific HIV incidence rates, evaluated adjusted risk ratios (aRR) for seroconversion using multivariable targeted maximum likelihood estimation, and assessed potential infection sources based on self-report. Results Of 704 seroconverters, 63% were women. Young (15-24 years) men comprised a larger proportion of seroconverters in Western Uganda (18%) than Eastern Uganda (6%) or Kenya (10%). After adjustment for other risk factors, men who were mobile [>= 1 month of prior year living outside community] (aRR:1.68; 95%CI:1.09,2.60) or who HIV tested at home vs. health fair (aRR:2.44; 95%CI:1.89,3.23) were more likely to seroconvert. Women who were aged <= 24 years (aRR:1.91; 95%CI:1.27,2.90), mobile (aRR:1.49; 95%CI:1.04,2.11), or reported a prior HIV test (aRR:1.34; 95%CI:1.06,1.70), or alcohol use (aRR:2.07; 95%CI:1.34,3.22) were more likely to seroconvert. Among survey responders (N = 607, 86%), suspected infection source was more likely for women than men to be >= 10 years older (28% versus 8%) or a spouse (51% vs. 31%) and less likely to be transactional sex (10% versus 16%). Conclusion In the context of universal testing and treatment, additional strategies tailored to regional variability are needed to address HIV infection risks of young women, alcohol users, mobile populations, and those engaged in transactional sex to further reduce HIV incidence rates.
DIREITO À SAÚDE E TRANSFORMAÇÃO SOCIAL  "RIGHTS TO HEALTH AND SOCIAL CHANGES"
Creators: name: Cilaine de Oliveira Guilherme Barros
name: Ruy de Jesus Marçal Carneiro
Publisher: name: Zenodo
Year: 2006

description: RESUMO            O direito à saúde, reconhecido expressamente como um direito fundamental na Declaração Universal dos Direitos Humanos, em 1948, busca ainda hoje sua efetivação, principalmente por meio de ações positivas do Estado. A ineficácia deste direito afronta dispositivos constitucionais, tais como os fundamentos e os objetivos, princípios estruturais de nossa República. O presente artigo enfoca a necessidade da materialização do direito à saúde, como um dos pressupostos para o desenvolvimento social e o progresso da humanidade, operando transformações indispensáveis que aproximam o homem e o Direito. Utilizam-se como embasamento os Princípios Fundamentais, previstos no Título I da Constituição Federal de 1988, bem como o Título VIII do mesmo documento – DA ORDEM SOCIAL -, além de Pactos Internacionais ratificados pelo Estado brasileiro. Palavras-chave: direito à saúde, Estado, reflexos sociais.
Additional file 1 of Young adults understanding and readiness to engage with palliative care: extending the reach of palliative care through a public health approach: a qualitative study
Creators: name: Mallon, Anita
name: Hasson, Felicity
name: Casson, Karen
name: Slater, Paul
name: McIlfatrick, Sonja
Publisher: name: figshare
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology

description: Additional file 1. Interview Items.
Finiteness of Hot Classical Scalar Field Theory and the Plasmon Damping Rate
Creators: name: Aarts, Gert
name: Smit, Jan
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the renormalizability of the classical $ϕ^4$ theory at finite temperature. We calculate the time-dependent two point function to two loop order and show that it can be rendered finite by the counterterms of the classical static theory. As an application the classical plasmon damping rate is found to be $γ= λ^2 T^2/1536 πm$. When we use the high temperature expression for $m$ given by dimensional reduction, the rate is found to agree with the quantum mechanical result.
description: 11 pages, 4 eps figures, minor typographic corrections and two references added
Evidence of large nuclear deformation of $^{32}$S$^{*}$ formed in $^{20}$Ne + $^{12}$C reaction
Creators: name: Dey, Aparajita
name: Bhattacharya, S.
name: Bhattacharya, C.
name: Banerjee, K.
name: Rana, T. K.
name: Kundu, S.
name: Mukhopadhyay, S.
name: Gupta, D.
name: Saha, R.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Deformations of hot composite $^{32}$S$^{*}$ formed in the reaction $^{20}$Ne ($\sim$ 7 -- 10 MeV/nucleon) + $^{12}$C have been estimated from the respective inclusive $α$-particle evaporation spectra. The estimated deformations for $^{32}$S$^{*}$ have been found to be much larger than the `normal' deformations of hot, rotating composites at similar excitations. This further confirms the formation of highly deformed long-lived configuration of $^{20}$Ne + $^{12}$C at high excitations ($\sim$ 70 -- 100 MeV) -- which was recently indicated from the analysis of the complex fragment emission data for the same system. Exclusive $α$-particle evaporation spectra from the decay of hot composite $^{32}$S$^{*}$ also show similar behaviour.
description: 9 pages, 6 figures
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 1162
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1162, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1162, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
title: From the South to the North
title: The circulation of Latin American dependency theories in the Federal Republic of Germany
titleType: Subtitle
Creators: name: Ruvituso, Clara I.
Publisher: name: Freie Universität Berlin
Year: 2019
Subjects: subject: Area studies
subject: circulation of knowledge
subject: dependency theories
subject: global North
subject: transregional entanglements
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::300 Sozialwissenschaften

description: Sociological research into the transregional North–South circulation of knowledge in the social sciences and humanities has tended to have a unidirectional bias to date. The standard assumption is that as a result of globalization, theories and methods are spread from the global North to the global South. Based on this premise, many of the studies of circulation focus on the transfer of knowledge in terms of ideas, traditions, authors and concepts from the North to the South. Thus far, little attention has been paid to the transregional circulation of theoretical approaches from the South to the North and their impact on the transformation of the European social sciences and humanities. Analysing the circulation of the Latin American dependency theories in the Federal Republic of Germany, this article addresses precisely this gap. The focus is on processes of institutional consolidation of area studies, North–South mobility, the translation-process into German, application in empirical research, modification and rejection. Focusing on this little-explored orientation regarding the circulation of knowledge, this article is in keeping with the current attempt to analyse transregional entanglements within European social sciences.
Effects of algerian nettle (Urtica dioica L.) on benign prostatic hyperplasia and their mechanism of action elucidation: in vivo and in silico approaches
Creators: name: Bougueroua, Karima
name: Boufadi, Mokhtaria Yasmina
name: Latreche, Batoul
name: Celik, Ismail
name: Gonzalez, Miguel Guerrero
name: Bounoua, Amina Doubbi
name: Bouras, Samir
name: Eissa, Ahmed
name: Zoeir, Ahmed
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: This study investigated the effect of Urtica dioica roots etheric extract (UDEE) on oxidative stress, and urine obstruction with histopathological examinations of prostatic and renal tissues,and suggests computational methods as a complementary method, to make a hypothesis on the overall effect of UDEE in the treatment of benign prostatic hyperplasia (BPH).Gas chromatography/mass spectrometry was utilised to characterise UDEE.BPH was induced in rats through daily subcutaneous injections of testosterone propionate. Rats were also orally administered UDEE or a vehicle. After four weeks, prostate weight, urine output, and biochemical markers were evaluated. UDEE treatment demonstrated significant regression of prostatic enlargement, improved biochemical and histopathological characteristics, and regulation of antioxidant activity levels. Phytosteroids stand out, act by inhibiting 5α-reductase and aromatase. This study provides an insight into treatment of BPH, demonstrating safety of this compound towards the kidney compared to finasteride without severe side effects.
Additional file 1: of Exon skipping for Duchenne muscular dystrophy: a systematic review and meta-analysis
Creators: name: Shimizu-Motohashi, Yuko
name: Murakami, Terumi
name: Kimura, En
name: Komaki, Hirofumi
name: Watanabe, Norio
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: PRISMA checklist, protocol, search term, meta-analyses on outcomes other than primary, and characteristics of excluded studies. (PDF 1341 kb)
Additional file 1 of Health insurance enrollment and vision health in rural China: an epidemiological survey
Creators: name: Yan, Xiaochang
name: Yao, Baoqun
name: Chen, Xi
name: Bo, Shaoye
name: Qin, Xuezheng
name: Yan, Hua
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1:
title: L'Atlas de la flore vaudoise : bilan 2020
title: L'Atlas de la flore vaudoise : bilan 2020
titleType: AlternativeTitle
Creators: name: Burgy, Sarah
name: Guénat, Jérémie
name: Magnin-Gonze, Joëlle
name: Ciardo, Franco
name: Bornand, Christophe
name: Clerc, Christian
name: Jotterand, Alain
name: Rometsch, Sibyl
Publisher: name: Unknown
Year: 0

description: L’Atlas de la flore vaudoise est un projet du Cercle vaudois de botanique qui a débuté en 2013 et qui aboutira, en 2022, à une publication illustrée et à un atlas en ligne (Bornand et al. 2015, Burgy et al. 2016, 2017, 2018, 2019, 2020). Cet article présente l’état des lieux du projet à la fin 2020 ainsi que les objectifs pour 2021.
Studies of the horizontal inhomogeneities in NO2 concentrations above a shipping lane using ground-based multi-axis differential optical absorption spectroscopy (MAX-DOAS) measurements and validation with airborne imaging DOAS measurements
Creators: name: Seyler, André
name: Meier, Andreas C.
name: Wittrock, Folkard
name: Kattner, Lisa
name: Mathieu-Üffing, Barbara
name: Peters, Enno
name: Richter, Andreas
name: Ruhtz, Thomas
name: Schönhardt, Anja
name: Schmolke, Stefan
name: Burrows, John P.
Publisher: name: Freie Universität Berlin
Year: 2019
Subjects: subject: NO2 concentration
subject: multi-axis differential optical absorption spectroscopy (MAX-DOAS)
subject: 500 Naturwissenschaften und Mathematik::500 Naturwissenschaften::500 Naturwissenschaften und Mathematik

description: This study describes a novel application of an “onion-peeling” approach to multi-axis differential optical absorption spectroscopy (MAX-DOAS) measurements of shipping emissions aiming at investigating the strong horizontal inhomogeneities in NO2 over a shipping lane. To monitor ship emissions on the main shipping route towards the port of Hamburg, a two-channel (UV and visible) MAX-DOAS instrument was deployed on the island Neuwerk in the German Bight, 6–7 km south of the main shipping lane. Utilizing the fact that the effective light path length in the atmosphere depends systematically on wavelength, simultaneous measurements and DOAS retrievals in the UV and visible spectral ranges are used to probe air masses at different horizontal distances to the instrument to estimate two-dimensional pollutant distributions. Two case studies have been selected to demonstrate the ability to derive the approximate plume positions in the observed area. A situation with northerly wind shows high NO2 concentrations close to the measurement site and low values in the north of the shipping lane. The opposite situation with southerly wind, unfavorable for the on-site in situ instrumentation, demonstrates the ability to detect enhanced NO2 concentrations several kilometers away from the instrument. Using a Gaussian plume model, in-plume NO2 volume mixing ratios can be derived from the MAX-DOAS measurements. For validation, a comparison to airborne imaging DOAS measurements during the NOSE campaign in July 2013 is performed, showing good agreement between the approximate plume position derived from the onion-peeling MAX-DOAS and the airborne measurements as well as between the derived in-plume NO2 volume mixing ratios (VMRs).
Young Stellar Populations Around SN1987A
Creators: name: Panagia, Nino
name: Romaniello, Martino
name: Scuderi, Salvatore
name: Kirshner, Robert P.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the results of a study of the stellar population in a region of 30 pc radius around SN1987A, based on an analysis of multi-band HST-WFPC2 images. The effective temperature, radius and, possibly, reddening of each star were determined for 21,955 stars by fitting the measured broad band magnitudes to the ones calculated with model atmospheres. In addition, we have identified all stars with Halpha equivalent widths in excess of 8 A, amounting to a total of 492 stars. An inspection to the HR diagram reveals the presence of several generations of young stars, with ages between 1 and 150 Myrs, superposed on a much older field population (0.6-6 Gyrs). A substantial fraction of young stars have ages around 12 Myrs which is the stellar generation coeval to SN 1987A progenitor. The youngest stars in the field appear to be strong-line T Tauri stars. This constitute the first positive detection of low mass (about 1-2 Mo) Pre Main Sequence (PMS) stars outside the Milky Way. Their positions in the HR diagram appear to require that star formation in the LMC occurs with accretion rates about 10 times higher than in the Milky Way, i.e. ~10^{-4} Mo/yr. SN1987A appears to belong to a loose, young cluster 12+/-2 Myrs old, in which the slope of the present mass function is almost identical to Salpeter's for masses above 3 Mo, but becomes much flatter for lower masses. On a large scale, we find that the spatial distribution of massive stars and low-mass PMS stars are conclusively different. This results casts doubts on the validity of an IMF concept on a small scale (say, less than 10 pc). A preliminary analysis, done for the whole field as a single entity, shows that the IMF slope for the young population present over the entire region is steeper than Gamma ~ -1.7.
description: 31 pages, 12 figures. Accepted for publication in the Astrophysical Journal. Please contact mromanie@eso.org for the full color version of the figures. Minor typos fixed, suffix of Figure 7b changed from ps to gif
title: Nuclear charge radii of ⁶²⁻⁸⁰Zn and their dependence on cross-shell proton excitations
Creators: name: Xie, Liang
name: Yang, Xiaofei
name: Bieron, Jacek
name: Wraith, Calvin
name: Flanagan, Kieran T.
name: Garcia Ruiz, R. F.
name: Gins, Wouter
name: Gaigalas, Gediminas
name: Godefroid, Michel
name: Gorges, Christian
name: Grob, L. K.
name: Heylen, Hanne
name: Jo̊nsson, Per
name: Kaufmann, Simon
name: Kowalska, Magdalena A.
name: Krämer, Jörg
name: Malbrunot-Ettenauer, S.
name: Neugart, Rainer
name: Neyens, Gerda
name: Nörtershäuser, Wilfried
name: Otsuka, Takaharu
name: Papuga, Jasna
name: Sánchez, Rodolfo M.
name: Tsunoda, Yusuke
name: Yordanov, Deyan Todorov
name: Babcock, Carla
name: Billowes, Jonathan
name: Bissell, Mark L.
name: Blaum, Klaus
name: Cheal, Bradley
name: Filippin, Livio
Publisher: name: Elsevier
Year: 2022

description: Nuclear charge radii of ⁶²⁻⁸⁰Zn have been determined using collinear laser spectroscopy of bunched ion beams at CERN-ISOLDE. The subtle variations of observed charge radii, both within one isotope and along the full range of neutron numbers, are found to be well described in terms of the proton excitations across the Z = 28 shell gap, as predicted by large-scale shell model calculations. It comprehensively explains the changes in isomer-to-ground state mean square charge radii of ⁶⁹⁻⁷⁹Zn, the inversion of the odd-even staggering around N = 40 and the odd-even staggering systematics of the Zn charge radii. With two protons above Z = 28, the observed charge radii of the Zn isotopic chain show a cumulative effect of different aspects of nuclear structure including single particle structure, shell closure, correlations and deformations near the proposed doubly magic nuclei, ⁶⁸Ni and ⁷⁸Ni.