cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
HIV-Related Stigma, Social Support, and Symptoms of Mental Health Disorders Among People with HIV Initiating HIV Care in Cameroon
Creators: name: Ebasone, P.V.
name: Pefura-Yone, E
name: Ajeh, R
name: Filiatreau, L.M.
name: Parcesepe, A.M.
name: Yotebieng, M.
name: Nash, D
name: Pence, B.W.
name: Wainberg, M.
name: Dzudie, A.
name: Anastos, K.
name: Nsame, D
name: Gomez, A.
Publisher: name: Mary Ann Liebert Inc.
Year: 2023

description: HIV-related stigma has been associated with poor mental health among people with HIV (PWH). Social support is a potentially modifiable factor that may buffer negative mental health sequelae of HIV-related stigma. Little is known about the extent to which the modifying effect of social support differs across mental health disorders. Interviews were conducted with 426 PWH in Cameroon. Log binomial regression analyses were used to estimate the association between high anticipated HIV-related stigma and low social support from family or friends and symptoms of depression, anxiety, post-traumatic stress disorder (PTSD), and harmful alcohol use, separately. Anticipated HIV-related stigma was commonly endorsed with ∼80% endorsing at least 1 of 12 stigma-related concerns. In multivariable analyses, high anticipated HIV-related stigma was associated with greater prevalence of symptoms of depression {adjusted prevalence ratio (aPR) 1.6 [95% confidence interval (CI) 1.1-2.2]} and anxiety [aPR 2.0 (95% CI 1.4-2.9)]. Low social support was associated with greater prevalence of symptoms of depression [aPR 1.5 (95% CI 1.1-2.2)], anxiety [aPR 1.7 (95% CI 1.2-2.5)], and PTSD [aPR 1.6 (95% CI 1.0-2.4)]. However, social support did not meaningfully modify the relationship between HIV-related stigma and symptoms of any mental health disorders explored. Anticipated HIV-related stigma was commonly reported among this group of PWH initiating HIV care in Cameroon. Social concerns related to gossip or losing friends were of the greatest concern. Interventions focused on reducing stigma and strengthening support systems may be particularly beneficial and have the potential to improve the mental health of PWH in Cameroon.
Asteroseismology for the Masses
Creators: name: Metcalfe, Travis S.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: For many years, astronomers interested in white dwarf stars have promised that the study of these relatively simple compact objects would ultimately lead to useful information about the physics under extreme conditions of temperature and pressure. We are finally ready to make good on that promise. Using the observational techniques of the Whole Earth Telescope developed over the past decade, and a new analytical method only recently made feasible by the availability of fast inexpensive computers, we demonstrate that meaningful constraints can now be made on the rates of important nuclear fusion reactions which cannot presently be measured in the laboratory.
description: To appear in Proceedings of the 12th European Workshop on White Dwarfs
title: ADCO, Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Cart. 198-01 (11 H 1055), 185 folios, f. 0160
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0160, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0160, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells
Creators: name: Yihua Wang
name: Xiong, Hua
name: Liu, Dian
name: Hill, Charlotte
name: Ayse Ertay
name: Juanjuan Li
name: Yanmei Zou
name: Miller, Paul
name: White, Eileen
name: Downward, Julian
name: Goldin, Robert D
name: Xianglin Yuan
name: Lu, Xin
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Model organisms
Tumour Biology
Signalling & Oncogenes
Gene Expression
Genetics & Genomics
Chemical Biology & High Throughput

description: Macroautophagy/autophagy inhibition is a novel anticancer therapeutic strategy, especially for tumors driven by mutant RAS. Here, we demonstrate that autophagy inhibition in RAS-mutated cells induces epithelial-mesenchymal transition (EMT), which is associated with enhanced tumor invasion. This is at least partially achieved by triggering the NFKB/NF-κB pathway via SQSTM1/p62. Knockdown of ATG3 or ATG5 increases oncogenic RAS-induced expression of ZEB1 and SNAI2/Snail2, and activates NFKB activity. Depletion of SQSTM1 abolishes the activation of the NFKB pathway induced by autophagy inhibition in RAS-mutated cells. NFKB pathway inhibition by depletion of RELA/p65 blocks this EMT induction. Finally, accumulation of SQSTM1 protein correlates with loss of CDH1/E-cadherin expression in pancreatic adenocarcinoma. Together, we suggest that combining autophagy inhibition with NFKB inhibitors may therefore be necessary to treat RAS-mutated cancer. Abbreviations: 4-OHT: 4-hydroxytamoxifen; DIC: differential interference contrast; EMT: epithelial-mesenchymal transition; ESR: estrogen receptor; MAPK/ERK: mitogen-activated protein kinase; iBMK: immortalized baby mouse kidney epithelial cells; MET: mesenchymal-epithelial transition; PI3K: phosphoinositide 3-kinase; RNAi: RNA interference; TGFB/TGF-β: transforming growth factor beta; TNF: tumor necrosis factor; TRAF6: TNF receptor associated factor 6.
Coping Strategies and Symptoms of Mental Health Disorders Among People with HIV Initiating HIV Care in Cameroon
Creators: name: Pefura-Yone, E
name: Dzudie, A.
name: Nash, D
name: Yotebieng, M.
name: Ajeh, R
name: Parcesepe, A.M.
name: Anastos, K.
name: Wainberg, M.
name: Ebasone, P.V.
name: Nsame, D
name: Pence, B.W.
name: Filiatreau, L.M.
name: Gomez, A.
Publisher: name: Springer
Year: 2023

description: Little is known about the coping strategies used among people with HIV (PWH), especially in sub-Saharan Africa, and the extent to which adaptive or maladaptive coping strategies are associated with symptoms of mental health disorders. We interviewed 426 PWH initiating HIV care in Cameroon and reported the prevalence of adaptive and maladaptive coping strategies, overall and by presence of symptoms of depression, anxiety, and PTSD. Log binominal regression was used to estimate the association between each type of coping strategy (adaptive or maladaptive) and symptoms of each mental health disorder, separately. Adaptive and maladaptive coping strategies were commonly reported among PWH enrolling in HIV care in Cameroon. Across all mental health disorders assessed, greater maladaptive coping was associated with higher prevalence of depression, anxiety, and PTSD. Adaptive coping was not associated with symptoms of any of the mental health disorders assessed in bivariate or multivariable models. Our study found that PWH endorsed a range of concurrent adaptive and maladaptive coping strategies. Future efforts should explore the extent to which coping strategies change throughout the HIV care continuum. Interventions to reduce maladaptive coping have the potential to improve the mental health of PWH in Cameroon.
Observation of Heteronuclear Feshbach Molecules from a $^{85}$Rb - $^{87}$Rb gas
Creators: name: Papp, S. B.
name: Wieman, C. E.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We report on the observation of ultracold heteronuclear Feshbach molecules. Starting with a $^{87}$Rb BEC and a cold atomic gas of $^{85}$Rb, we utilize previously unobserved interspecies Feshbach resonances to create up to 25,000 molecules. Even though the $^{85}$Rb gas is non-degenerate we observe a large molecular conversion efficiency due to the presence of a quantum degenerate $^{87}$Rb gas; this represents a key feature of our system. We compare the molecule creation at two different Feshbach resonances with different magnetic-field widths. The two Feshbach resonances are located at $265.44\pm0.15$ G and $372.4\pm1.3$ G. We also directly measure the small binding energy of the molecules through resonant magnetic-field association.
description: v2 - minor changes
Additional file 1 of School-based surveillance of acute infectious disease in children: a systematic review
Creators: name: Donaldson, A. L.
name: Hardstaff, J. L.
name: Harris, J. P.
name: Vivancos, R.
name: O’Brien, S. J.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Search terms by database. Details of search terms used by database
Multi-electron giant dipole resonances of atoms in crossed electric and magnetic fields
Creators: name: Zöllner, S.
name: Meyer, H. -D.
name: Schmelcher, P.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Multi-electron giant dipole resonances of atoms in crossed electric and magnetic fields are investigated. Stationary configurations corresponding to a highly symmetric arrangement of the electrons on a decentered circle are derived, and a normal-mode stability analysis is performed. A classification of the various modes, which are dominated either by the magnetic or Coulomb interactions, is provided. A six-dimensional wave-packet dynamical study, based on the MCTDH approach, is accomplished for the two-electron resonances, yielding in particular lifetimes of more than 0.1 $μ$s for strong electric fields.
description: 7 pages, 3 figures
Quantifying the AGN-driven outflows in ULIRGs (QUADROS) I: VLT/Xshooter observations of 9 nearby objects
Creators: name: Rose, Marvin
name: Tadhunter, Clive
name: Almeida, Cristina Ramos
name: Zaurin, Javier Rodriguez
name: Santoro, Francesco
name: Spence, Robert
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Although now routinely incorporated into hydrodynamic simulations of galaxy evolution, the true importance of the feedback effect of the outflows driven by active galactic nuclei (AGN) remains uncertain from an observational perspective. This is due to a lack of accurate information on the densities, radial scales and level of dust extinction of the outflow regions. Here we use the unique capabilities of VLT/Xshooter to investigate the warm outflows in a representative sample of 9 local (0.06 $
description: 31 pages, 12 figures, 21 tables, accepted for publication in MNRAS
Chandra measurements of the distribution of mass in the luminous lensing cluster Abell 2390
Creators: name: Allen, S. W.
name: Ettori, S.
name: Fabian, A. C.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present spatially-resolved X-ray spectroscopy of the luminous lensing cluster Abell 2390, using observations made with the Chandra observatory. The temperature of the X-ray gas is shown to rise with increasing radius within the central ~200 kpc of the cluster, and then remain approximately isothermal, with kT =11.5^{+1.5}_{-1.6} keV, out to the limits of the observations at r~1.0 Mpc. The total mass profile determined from the Chandra data has a form in good agreement with the predictions from numerical simulations. Using the parameterization of Navarro, Frenk & White (1997), we measure a scale radius r_s~0.9 Mpc and a concentration parameter c~4. The best-fit X-ray mass model is in good agreement with independent gravitational lensing results and optical measurements of the galaxy velocity dispersion in the cluster. The X-ray gas-to-total-mass ratio rises with increasing radius with f_gas = 21 \pm 10 per cent at r=0.9 Mpc. The azimuthally-averaged 0.3-7.0 keV surface brightness profile exhibits a small core radius and a clear `break' at r~500 kpc, where the slope changes from S_X \approxpropto r^{-1.5} to S_X \approxpropto r^{-3.6}. The data for the central region of the cluster indicate the presence of a cooling flow with a mass deposition rate of 200-300 solar masses per year and an age of 2-3 Gyr.
description: 24 pages, 12 figs, 3 tables. Accepted for publication in MNRAS. Some improvements over original submitted version including enhanced X-ray mass analysis
Alcohol use as a mediator of the effect of two alcohol reduction interventions on mental health symptoms of ART clients in Vietnam
Creators: name: Chander, G.
name: Muessig, K.E.
name: Dowdy, D.
name: Pence, B.W.
name: Latkin, C.A.
name: Frangakis, C
name: Hutton, H.
name: Tran, H.V
name: Sripaipan, T
name: Go, V.F
name: Nguyen, M.X.
name: Reyes, H.L.
name: Lancaster, K.E.
Publisher: name: Routledge
Year: 2023

description: We aimed to examine the mediating role of alcohol use in the pathway from the interventions to depression and anxiety symptoms using data from a randomized controlled trial among people living with HIV (PWH) with hazardous alcohol use (n = 440) in Thai Nguyen, Vietnam. Participants were randomized into either a combined intervention (CoI), a brief intervention (BI) and a standard of care arm. Both interventions were based on cognitive behavioral therapy and motivational enhancement therapy. Alcohol use was measured as the percentage of days abstinent from alcohol in the last 30 days. Symptoms of depression and anxiety were measured with the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scales. Alcohol use was a significant mediator of the effects of two alcohol interventions on depression symptoms, but not anxiety symptoms. There were significant indirect effects via alcohol use of both interventions on depression symptoms at 12 months (CoI: mean difference (MD) = −0.134; 95%CI: −0.251, −0.035); (BI: MD = −0.141; 95%CI: −0.261, −0.038). There were no significant direct or total effects of the interventions on either symptoms at 12 months. Interventions with a dual focus on mental health and alcohol disorders are needed to determine optimal ways to tackle these common comorbidities among PWH.
Additional file 4: of The 2016 Mw 5.9 earthquake off the southeastern coast of Mie Prefecture as an indicator of preparatory processes of the next Nankai Trough megathrust earthquake
Creators: name: Nakano, Masaru
name: Hyodo, Mamoru
name: Nakanishi, Ayako
name: Mikiya Yamashita
name: Takane Hori
name: Shin-Ichiro Kamiya
name: Suzuki, Kensuke
name: Tonegawa, Takashi
name: Kodaira, Shuichi
name: Takahashi, Narumi
name: Kaneda, Yoshiyuki
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Marine Biology

description: Supplementary note. (DOCX 35Â kb)
Prevalence of potentially traumatic events and symptoms of depression, anxiety, hazardous alcohol use, and post-traumatic stress disorder among people with HIV initiating HIV care in Cameroon
Creators: name: Dzudie, A.
name: Filiatreau, L.M.
name: Ajeh, R
name: Anastos, K.
name: Pefura-Yone, E.
name: Yotebieng, M.
name: Pence, B.W.
name: Ebasone, P.V.
name: Parcesepe, A.M.
name: Nash, D
name: Nsame, D
name: Wainberg, M.
Publisher: name: BioMed Central Ltd
Year: 2023

description: Background: This study explored the relationship between specific types of potentially traumatic events (PTEs) and symptoms of mental health disorders among people with HIV (PWH) in Cameroon. Methods: We conducted a cross-sectional study with 426 PWH in Cameroon between 2019–2020. Multivariable log binominal regression was used to estimate the association between exposure (yes/no) to six distinct types of PTE and symptoms of depression (Patient Health Questionnaire-9 score > 9), PTSD (PTSD Checklist for DSM-5 score > 30), anxiety (Generalized Anxiety Disorder-7 scale score > 9), and hazardous alcohol use (Alcohol Use Disorders Identification Test score > 7 for men; > 6 for women). Results: A majority of study participants (96%) reported exposure to at least one PTE, with a median of 4 PTEs (interquartile range: 2–5). The most commonly reported PTEs were seeing someone seriously injured or killed (45%), family members hitting or harming one another as a child (43%), physical assault or abuse from an intimate partner (42%) and witnessing physical assault or abuse (41%). In multivariable analyses, the prevalence of PTSD symptoms was significantly higher among those who reported experiencing PTEs during childhood, violent PTEs during adulthood, and the death of a child. The prevalence of anxiety symptoms was significantly higher among those who reported experiencing both PTEs during childhood and violent PTEs during adulthood. No significant positive associations were observed between specific PTEs explored and symptoms of depression or hazardous alcohol use after adjustment. Conclusions: PTEs were common among this sample of PWH in Cameroon and associated with PTSD and anxiety symptoms. Research is needed to foster primary prevention of PTEs and to address the mental health sequelae of PTEs among PWH.
Additional file 2 of School-based surveillance of acute infectious disease in children: a systematic review
Creators: name: Donaldson, A. L.
name: Hardstaff, J. L.
name: Harris, J. P.
name: Vivancos, R.
name: O’Brien, S. J.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Data extraction form. Standardised form used in the data extraction process
Waiting time distribution revealing the internal spin dynamics in a double quantum dot
Creators: name: Ptaszynski, Krzysztof
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Waiting time distribution and the zero-frequency full counting statistics of unidirectional electron transport through a double quantum dot molecule attached to spin-polarized leads are analyzed using the quantum master equation. The waiting time distribution exhibits a non-trivial dependence on the value of the exchange coupling between the dots and the gradient of the applied magnetic field, which reveals the oscillations between the spin states of the molecule. The zero-frequency full counting statistics, on the other hand, is independent of the aforementioned quantities, thus giving no insight into the internal dynamics. The fact that the waiting time distribution and the zero-frequency full counting statistics give a non-equivalent information is associated with two factors. Firstly, it can be explained by the sensitivity to different timescales of the dynamics of the system. Secondly, it is associated with the presence of the correlation between subsequent waiting times, which makes the renewal theory, relating the full counting statistics and the waiting time distribution, not longer applicable. The study highlights the particular usefulness of the waiting time distribution for the analysis of the internal dynamics of mesoscopic systems.
description: 16 pages, 12 figures. Accepted for publication in Phys. Rev. B
Biomechanical analysis of a cranial Patient Specific Implant on the interface with the bone using the Finite Element Method
Creators: name: Díaz, J.
name: González-Estrada, Octavio Andrés
name: López, C.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Medical Physics (physics.med-ph)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: - New advance technologies based on reverse engineering , design and additive manufacturing, have expanded design capabilities for biomedical applications to include Patient Specific Implants (PSI). This change in design paradigms needs advanced tools to assess the mechanical performance of the product, and simulate the impact on the patient. In this work, we perform a structural analysis on the interface of a cranial PSI under static loading conditions. Based on those simulations, we have identified the regions with high stress and strain and checked the failure criteria both in the implant and the skull. We evaluate the quality of the design of the implant and determine their response given different materials, in order to ensure optimality of the final product to be manufactured .
Clustering of phosphorus atoms in silicon
Creators: name: Velichko, O. I.
name: Sobolevskaya, N. A.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: To explain the effect of electron density saturation at high phosphorus concentrations the model of negatively charged phosphorus clusters was compared with the experimental data. A number of negatively charged clusters incorporating a point defect and phosphorus atoms were investigated at temperatures of 920 and 1000 Celsius degrees. It was established that for clusters incorporating more than one phosphorus atom calculated electron density reached a maximum value and then monotonically and slowly decreased with increasing the total dopant concentration. If the cluster incorporates 3-4 phosphorus atoms the calculated dependencies of carrier concentration agree well with the experimental data for both temperatures regardless of the negative charge state of the cluster (- or 2-). Moreover, for all investigated doubly negatively charged clusters the fitting parameter is independent on the temperature. It means that formation of doubly negatively charged clusters is most likely but it is difficult to choose between clusters incorporating two, three or four phosphorus atoms. From a good agreement of the calculated curves with the experiments it follows that the model based on the formation of negatively charged clusters can be used in simulation of high concentration phosphorus diffusion.
description: 16 pages, 6 figures, LaTex
Massless Flows I: the sine-Gordon and O(n) models
Creators: name: Fendley, P.
name: Saleur, H.
name: Zamolodchikov, Al. B.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The massless flow between successive minimal models of conformal field theory is related to a flow within the sine-Gordon model when the coefficient of the cosine potential is imaginary. This flow is studied, partly numerically, from three different points of view. First we work out the expansion close to the Kosterlitz-Thouless point, and obtain roaming behavior, with the central charge going up and down in between the UV and IR values of $c=1$. Next we analytically continue the Casimir energy of the massive flow (i.e. with real cosine term). Finally we consider the lattice regularization provided by the O(n) model in which massive and massless flows correspond to high- and low-temperature phases. A detailed discussion of the case $n=0$ is then given using the underlying N=2 supersymmetry, which is spontaneously broken in the low-temperature phase. The ``index'' $\tr F(-1)^F$ follows from the Painleve III differential equation, and is shown to have simple poles in this phase. These poles are interpreted as occuring from level crossing (one-dimensional phase transitions for polymers). As an application, new exact results for the connectivity constants of polymer graphs on cylinders are obtained.
description: 39 pages, 7 uuencoded figures, BUHEP-93-5, USC-93/003, LPM-93-07
The acceptability of antidepressant treatment in people living with HIV in Malawi: A patient perspective
Creators: name: Sansbury, G.
name: Hosseinipour, M.C.
name: Stockton, M.A.
name: Kulisewa, K.
name: Minnick, C.E.
name: Gaynes, B.N.
name: Udedi, M.M.
name: Mphonda, S.
name: Pence, B.W.
Publisher: name: Taylor and Francis Ltd.
Year: 2023

description: Depression is common among people living with HIV (PLWH). Measurement-based care models that measure depression severity and antidepressant side effects, and use an algorithm to guide antidepressant prescription by non-specialized health workers represent an evidence-based treatment for severe depression in sub-Saharan Africa. We conducted in-depth interviews from June to December 2018 with eleven patients enrolled in Project SOAR-Mental Health, a pilot project integrating depression treatment into HIV care in Malawi. Patients treated with amitriptyline or fluoxetine participated in interviews exploring antidepressant acceptability through patient knowledge, side effect severity, pill burden, adherence, perceived efficacy, and tolerability. Patients described a lack of detailed antidepressant education from their providers. Variable, typically self-limiting side effects were reported from both amitriptyline and fluoxetine. While most side effects were mild, three patients reported functional impairment. Patients reported high adherence, though the additional pill burden was a challenge. Most patients found the antidepressants efficacious, tolerable, beneficial and acceptable. Although patient psychoeducation is notably lacking as a facet of clinical management, antidepressant prescription by primary care providers appears acceptable for comorbid severe depression in PLWH initiating HIV care in sub-Saharan Africa. Health workers should be mindful of dosing to minimise side effects and considerate of the additional pill burden. Trial registration: ClinicalTrials.gov ID [NCT03555669]. Retrospectively registered on 13 June 2018.
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 602
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 602, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 602, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin
Creators: name: Smythies, James A
name: Sun, Min
name: Masson, Norma
name: Salama, Rafik
name: Simpson, Peter D
name: Murray, Elizabeth
name: Neumann, Viviana
name: Cockman, Matthew E
name: Choudhry, Hani
name: Ratcliffe, Peter J
name: Mole, David R
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Biochemistry & Proteomics
Metabolism
Cell Biology
Signalling & Oncogenes

description: Hypoxia-inducible factor (HIF) is the major transcriptional regulator of cellular responses to hypoxia. The two principal HIF-α isoforms, HIF-1α and HIF-2α, are progressively stabilized in response to hypoxia and form heterodimers with HIF-1β to activate a broad range of transcriptional responses. Here, we report on the pan-genomic distribution of isoform-specific HIF binding in response to hypoxia of varying severity and duration, and in response to genetic ablation of each HIF-α isoform. Our findings reveal that, despite an identical consensus recognition sequence in DNA, each HIF heterodimer loads progressively at a distinct repertoire of cell-type-specific sites across the genome, with little evidence of redistribution under any of the conditions examined. Marked biases towards promoter-proximal binding of HIF-1 and promoter-distant binding of HIF-2 were observed under all conditions and were consistent in multiple cell type. The findings imply that each HIF isoform has an inherent property that determines its binding distribution across the genome, which might be exploited to therapeutically target the specific transcriptional output of each isoform independently.
Additional file 1 of Resilience and its associated factors in head and neck cancer patients in Pakistan: an analytical cross-sectional study
Creators: name: Zahid, Nida
name: Zahid, Wajeeha
name: Khalid, Wardah
name: Azam, Iqbal
name: Ikram, Mubasher
name: Hassan, Aneesa
name: Iftikar, Haissan
name: Bhamani, Shireen Shehzad
name: Jabbar, Adnan Abdul
name: Akhtar, Shabbir
name: Siddiqui, Moghira Iqbaluddin
name: Awan, Mohammad Sohail
name: Asad, Nargis
name: Ahmad, Khabir
Publisher: name: figshare
Year: 2021
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
Beyond Viral Suppression - The Impact of Cumulative Violence on Health-Related Quality of Life among a Cohort of Virally Suppressed Patients
Creators: name: Mills, J.C.
name: Harris, R.M.
name: Pence, B.W.
name: Bgneris, J.
name: Xavier Hall, C.D.
name: Wong, F.Y.
Publisher: name: Wolters Kluwer Health
Year: 2023

description: Objective:To elucidate how and in what ways cumulative violence affects health-related quality of life (HRQoL) among a clinical cohort of virally stable people living with HIV.Design:We used data from the University of North Carolina Center for AIDS Research HIV clinical cohort. Our analysis was limited to participants with an undetectable viral load (<200) and those who completed the Clinical, Sociodemographic, and Behavioral Survey between 2008 and 2017 (n = 284).Methods:A path analysis was used to test our primary hypothesis that the effect of cumulative violence on HRQoL would be mediated through symptoms of post-traumatic stress disorder (PTSD), depressive symptoms, and HIV symptom distress.Results:The impact of cumulative violence on HRQoL was fully mediated by symptoms of PTSD, depressive symptoms, and HIV symptom distress. Greater exposure to violence was associated with higher odds of PTSD symptoms (P <0.001), increased depressive symptoms (P <0.001), and increased HIV symptom distress (P < 0.01). HIV symptom distress displayed the largest association with HRQoL (P < 0.001), followed by depressive symptoms (P = 0.001) and PTSD symptoms (P < 0.001). These factors explained approximately 51% of the variance in HRQoL (R2= 0.51, P < 0.001).Conclusions:Our findings indicate that addressing physical and mental health symptoms rooted in violent victimization should be a point of focus in efforts to improve HRQoL among people living with HIV who are virally stable.
MOESM1 of In silico reconstruction and experimental validation of Saccharopolyspora erythraea genome-scale metabolic model iZZ1342 that accounts for 1685 ORFs
Creators: name: Zhendong Zhuang
name: Mingzhi Huang
name: Chu, Ju
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Computational Biology

description: Additional file 1. Information of databases used in this study.
Particle reacceleration in Coma cluster: radio properties and hard X-ray emission
Creators: name: Brunetti, G.
name: Setti, G.
name: Feretti, L.
name: Giovannini, G.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The radio spectral index map of the Coma halo shows a progressive steepening of the spectral index with increasing radius. Such a steepening cannot be simply justified by models involving continuous injection of fresh particles in the Coma halo or by models involving diffusion of fresh electrons from the central regions. We propose a {\it two phase} model in which the relativistic electrons injected in the Coma cluster by some processes (starbursts, AGNs, shocks, turbulence) during a {\it first phase} in the past are systematically reaccelerated during a {\it second phase} for a relatively long time ($\sim$ 1 Gyr) up to the present time. We show that for reacceleration time scales of $\sim 0.1$ Gyr this hypothesis can well account for the radio properties of Coma C. For the same range of parameters which explain Coma C we have calculated the expected fluxes from the inverse Compton scattering of the CMB photons finding that the hard X-ray tail discovered by BeppoSAX may be accounted for by the stronger reacceleration allowed by the model. The possibility of extending the main model assumptions and findings to the case of the other radio haloes is also discussed, the basic predictions being consistent with the observations.
description: 15 pages, 13 figures, accepted for publication in MNRAS
Real-time colouring and filtering with graphics shaders
Creators: name: Vohl, Dany
name: Fluke, Christopher J.
name: Barnes, David G.
name: Hassan, Amr H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Despite the popularity of the Graphics Processing Unit (GPU) for general purpose computing, one should not forget about the practicality of the GPU for fast scientific visualisation. As astronomers have increasing access to three dimensional (3D) data from instruments and facilities like integral field units and radio interferometers, visualisation techniques such as volume rendering offer means to quickly explore spectral cubes as a whole. As most 3D visualisation techniques have been developed in fields of research like medical imaging and fluid dynamics, many transfer functions are not optimal for astronomical data. We demonstrate how transfer functions and graphics shaders can be exploited to provide new astronomy-specific explorative colouring methods. We present 12 shaders, including four novel transfer functions specifically designed to produce intuitive and informative 3D visualisations of spectral cube data. We compare their utility to classic colour mapping. The remaining shaders highlight how common computation like filtering, smoothing and line ratio algorithms can be integrated as part of the graphics pipeline. We discuss how this can be achieved by utilising the parallelism of modern GPUs along with a shading language, letting astronomers apply these new techniques at interactive frame rates. All shaders investigated in this work are included in the open source software shwirl (Vohl, 2017).
description: 24 pages, 19 figures, 14 algorithms, 1 table. Accepted for publication by Monthly Notices of the Royal Astronomical Society
Additional file 1 of Prevalence and management of driveline infections in mechanical circulatory support - a single center analysis
Creators: name: Juraszek, Andrzej
name: Smólski, Mikołaj
name: Kołsut, Piotr
name: Szymański, Jarosław
name: Litwiński, Paweł
name: Kuśmierski, Krzysztof
name: Zakrzewska-Koperska, Joanna
name: Sterliński, Maciej
name: Dziodzio, Tomasz
name: Kuśmierczyk, Mariusz
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1. Pathogens and detailed antibiotic therapy.
Associations of disordered eating with the intestinal microbiota and short-chain fatty acids among young adults with type 1 diabetes
Creators: name: Corbin, K.D.
name: Bulik, C.M.
name: Maahs, D.M
name: Zaharieva, D.P.
name: Carroll, I.M
name: Addala, A.
name: Igudesman, D.
name: Mayer-Davis, E.J
name: Pence, B.W.
name: Crandell, J.
name: Pratley, R.E.
name: Thomas, J.M.
name: Kosorok, M.R
Publisher: name: Elsevier B.V.
Year: 2023

description: Background and aims: Disordered eating (DE) in type 1 diabetes (T1D) includes insulin restriction for weight loss with serious complications. Gut microbiota-derived short chain fatty acids (SCFA) may benefit host metabolism but are reduced in T1D. We evaluated the hypothesis that DE and insulin restriction were associated with reduced SCFA-producing gut microbes, SCFA, and intestinal microbial diversity in adults with T1D. Methods and results: We collected stool samples at four timepoints in a hypothesis-generating gut microbiome pilot study ancillary to a weight management pilot in young adults with T1D. 16S ribosomal RNA gene sequencing measured the normalized abundance of SCFA-producing intestinal microbes. Gas-chromatography mass-spectrometry measured SCFA (total, acetate, butyrate, and propionate). The Diabetes Eating Problem Survey—Revised (DEPS-R) assessed DE and insulin restriction. Covariate-adjusted and Bonferroni-corrected generalized estimating equations modeled the associations. COVID-19 interrupted data collection, so models were repeated restricted to pre-COVID-19 data. Data were available for 45 participants at 109 visits, which included 42 participants at 65 visits pre-COVID-19. Participants reported restricting insulin “At least sometimes” at 53.3% of visits. Pre-COVID-19, each 5-point DEPS-R increase was associated with a −0.34 (95% CI -0.56, −0.13, p = 0.07) lower normalized abundance of genus Anaerostipes; and the normalized abundance of Lachnospira genus was −0.94 (95% CI -1.5, −0.42), p = 0.02 lower when insulin restriction was reported “At least sometimes” compared to “Rarely or Never”. Conclusion: DE and insulin restriction were associated with a reduced abundance of SCFA-producing gut microbes pre-COVID-19. Additional studies are needed to confirm these associations to inform microbiota-based therapies in T1D.
Wetting properties of structured interfaces composed of surface-attached spherical nanoparticles
Creators: name: Bhattarai, Bishal
name: Priezjev, Nikolai V.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Computational Physics (physics.comp-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The influence of the external pressure and surface energy on the wetting transition at nanotextured interfaces is studied using molecular dynamics and continuum simulations. The surface roughness of the composite interface is introduced via an array of spherical nanoparticles with controlled wettability. We find that in the absence of an external pressure, the liquid interface is flat and its location relative to the solid substrate is determined by the particle size and the local contact angle. With increasing pressure on the liquid film, the interface becomes more curved and the three-phase contact line is displaced along the spherical surface but remains stable due to re-entrant geometry. It is demonstrated that the results of molecular dynamics simulations for the critical pressure of the Cassie-Baxter wetting state agree well with the estimate of the critical pressure obtained by numerical minimization of the interfacial energy.
description: 23 pages, 9 figures
Additional file 3: of Effectiveness and sustainability of a structured group-based educational program (MEDIHEALTH) in improving medication adherence among Malay patients with underlying type 2 diabetes mellitus in Sarawak State of Malaysia: study protocol of a randomized controlled trial
Creators: name: Chuo Ting
name: Shahren Ahmad Zaidi Adruce
name: Hassali, Mohamed
name: Hiram Ting
name: Lim, Chien
name: Ting, Rachel Sing-Kiat
name: Jabar, Abu Abd
name: Nor Osman
name: Izzul Shuib
name: Shing Loo
name: Sim, Sui
name: Lim, Su
name: Morisky, Donald
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Facilitator competency and inter-coder reliability assessment form. (PDF 300Â kb)
title: 01_2318
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Undifferentiated sarcomas develop through distinct evolutionary pathways
Creators: name: Steele, Christopher D
name: Tarabichi, Maxime
name: Dahmane Oukrif
name: Webster, Amy P
name: Hongtao Ye
name: Fittall, Matthew
name: Lombard, Patrick
name: Iñigo Martincorena
name: Tarpey, Patrick S
name: Collord, Grace
name: Haase, Kerstin
name: Strauss, Sandra J
name: Berisha, Fitim
name: Vaikkinen, Heli
name: Dhami, Pawan
name: Jansen, Marnix
name: Behjati, Sam
name: M Fernanda Amary
name: Tirabosco, Roberto
name: Feber, Andrew
name: Campbell, Peter J
name: Alexandrov, Ludmil B
name: Loo, Peter Van
name: Flanagan, Adrienne M
name: Nischalan Pillay
Publisher: name: The Francis Crick Institute
Year: 2019
Subjects: Genetics & Genomics
Human Biology & Physiology
Ecology,Evolution & Ethology
Tumour Biology
Computational & Systems Biology

description: Undifferentiated sarcomas (USARCs) of adults are diverse, rare, and aggressive soft tissue cancers. Recent sequencing efforts have confirmed that USARCs exhibit one of the highest burdens of structural aberrations across human cancer. Here, we sought to unravel the molecular basis of the structural complexity in USARCs by integrating DNA sequencing, ploidy analysis, gene expression, and methylation profiling. We identified whole genome duplication as a prevalent and pernicious force in USARC tumorigenesis. Using mathematical deconvolution strategies to unravel the complex copy-number profiles and mutational timing models we infer distinct evolutionary pathways of these rare cancers. In addition, 15% of tumors exhibited raised mutational burdens that correlated with gene expression signatures of immune infiltration, and good prognosis.
Inverse spin Hall effect in Nd doped SrTiO3
Creators: name: Wang, Qiuru
name: Zhang, Wenxu
name: Peng, Bin
name: Zhang, Wanli
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Conversion of spin to charge current was observed in SrTiO3 doped with Nd (Nd:STO), which exhibited a metallic behavior even with low concentration doping. The obvious variation of DC voltages for Py/Nd:STO, obtained by inverting the spin diffusion direction, demonstrated that the detected signals contained the contribution from the inverse spin Hall effect (ISHE) induced by the spin dependent scattering from Nd impurities with strong spin-orbit interaction. The DC voltages of the ISHE for Nd:STO were measured at different microwave frequency and power, which revealed that spin currents were successfully injected into doped STO layer by spin pumping. The linear relation between the ISHE resistivity and the resistivity induced by impurities implied that the skew scattering was the dominant contribution in this case, and the spin Hall angle was estimated to be 0.17%. This work demonstrated that extrinsic spin dependent scattering in oxides can be used in spintroics besides that in heavy elements doped metals.