cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Ẓafār
title: Ẓafār
titleType: AlternativeTitle
title: Ẓafâr
titleType: AlternativeTitle
title: Zafār
titleType: AlternativeTitle
title: Zafâr
titleType: AlternativeTitle
title: Zafar
titleType: AlternativeTitle
title: Ẓfr
titleType: AlternativeTitle
Creators: name: Robin, Christian J.
name: Yule, Paul A.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: Zafar
South Arabia
Yemen
Pre-Islamic period
Settlement
Place name

description: Robin, Christian J. & Paul A. Yule, 2023. "Ẓafār". Thematic Dictionary of Ancient Arabia. Online edition 2023.
description: Source: https://doi.org/10.60667/tdaa-0153
description: Robin, Christian J. & Paul A. Yule, 2023. "Ẓafār". Thematic Dictionary of Ancient Arabia. Online edition 2023.
Monitoring protein structure and dynamics by optical proteomics: applications of site-specific labelling of FGFR in vitro
Creators: name: Perdios, Louis
Publisher: name: Imperial College London
Year: 2015

description: Imaging of protein tyrosine kinase activity requires negligibly intrusive, molecularly precise optical probes to provide spatiotemporal insights on conformational dynamics appertained to receptor dimerization and activation, which govern the engagement of downstream signalling networks in cancer and other pathologies. We present two sets of constructs with genetically encoded, site-specifically incorporated, bioorthogonal reporters that can be selectively labelled with exogenous fluorogenic probes to monitor the structure and function of an oncogenic tyrosine kinase, fibroblast growth factor receptor 1 (FGFR1). In this study, the conformational changes in the kinase domain of FGFR1 (FGFR1K) were monitored by imaging technologies that afford analysis at great spatial and temporal resolution. First, a novel set of recombinant constructs was engineered allowing the incorporation of BCNK, a bicyclononyne-containing, lysine-like unnatural amino acid (UAA) into the activation loop or the kinase insert region of FGFR1K. BCNK incorporation was accomplished by genetic code expansion, in which an evolved tRNA/synthetase pair from Methanosarcina species directed the site-specific installation of the UAA in response to an amber codon by orthogonal translation. We report here for the first time the efficient labelling of FGFR1K via fluorogenic bioorthogonal Diels-Alder cycloadditions using a tetramethylrhodamine dienophile, Tet1-TAMRA-X. We developed a single molecule Förster resonance energy transfer (smFRET) assay that uses an alternating laser excitation (ALEX) scheme in association with a surface immobilization strategy to examine changes in the conformational states of FGFR1K. FRET efficiency distributions and interdye distances provide evidence of large-amplitude domain motions in the tyrosine kinase domain and can be correlated to autophosphorylation-dependent changes in conformational states of FGFR1. The second construct, GyrB.FGFR1K3Y.TC, comprises a coumermycin-induced artificial dimerizer (GyrB), FGFR1K exhibiting wild-type like intrinsic kinase activity and a TC motif that enables fluorescent labelling with the biarsenicals FlAsH-EDT2 and REAsH-EDT2. We conceived bimolecular systems for in vitro studies by implementing time-resolved fluorescence lifetime imaging technologies. Our approach allowed examination of the interaction between GyrB.FGFR1K3Y.TC and N-terminal Src homology 2 (nSH2) domain of phospholipase C-γ (PLCγ), a downstream effector of FGFR1, fused to mTurquoise Fluorescent Protein (mTFP). Furthermore, we were able to probe FGFR1 dimerization by artificially inducing dimerization of GyrB using a chemical agent. We report here phosphorylation-dependent FRET readout of complex formation between mTFP.nSH2 and GyrB.FGFR1K3Y.TC as well as artificial dimerization of GyrB.FGFR1K3Y.TC.
Neutron-proton scattering with lattice chiral effective field theory at next-to-next-to-next-to-leading order
Creators: name: Li, Ning
name: Elhatisari, Serdar
name: Epelbaum, Evgeny
name: Lee, Dean
name: Lu, Bing-Nan
name: Meißner, Ulf-G.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We present a new lattice formulation of chiral effective field theory interactions with a simpler decomposition into spin channels. With these interactions the process of fitting to the empirical scattering phase shifts is simplified, and the resulting lattice phase shifts are more accurate than in previous studies. We present results for the neutron-proton system up to next-to-next-to-next-to-leading order for lattice spacings of $1.97$, $1.64$, $1.32$, and $0.99~{\rm fm}$. Our results provide a pathway to $\textit{ab initio}$ lattice calculations of nuclear structure, reactions, and thermodynamics with accurate and systematic control over the chiral nucleon-nucleon force.
description: 24 pages, 14 figures and 2 tables. Published in Physical Review C
Ranunculus lingua Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus lingua

description: Ranunculus lingua, spec. nov.
 3. Ranunculus foliis lanceolatis, caule erecto. Hort. cliff. 228. Fl. suec. 457. Roy. lugdb. 489. Dalib. paris. 163.
 Ranunculus longifolius palustris major. Bauh. pin. 34.
 Ranunculus lanceolatus major. Tabern. ic. 48.
 Habitat in Europae borealioris fossis, aquis limosis. ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 549, DOI: 10.5281/zenodo.3931989
A VLA Study of 15 3CR Radio Galaxies
Creators: name: Harvanek, Michael
name: Hardcastle, Martin J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present VLA radio maps in total intensity and polarization at 1.4, 4.9 and 8.4 GHz of fifteen 3CR radio galaxies for which good maps showing the large-scale radio structure have not previously been available. Previously unknown cores are detected in several sources and a bright one-sided jet in 3C 287.1 is mapped for the first time; several other jet-like features are also imaged. Total and core fluxes are tabulated and radio core positions are listed and compared to optical positions. The galaxy at the optical position listed for 3C 169.1 is found to lie farther from the radio core position than another dimmer, bluer galaxy. We discuss individual sources in some detail.
description: 35 pages, 22 figures but 35 separate Postscript figure files, AASTeX, Accepted for publication in the Astrophysical Journal Supplement
Ranunculus lingua Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus lingua

description: Ranunculus lingua Linnaeus, Species Plantarum 1: 549. 1753.
"Habitat in Europae borealioris fossis, aquis limosis." RCN: 4062.
Lectotype (Iranshahr & al. in Rechinger, Fl. Iranica 171: 169. 1992): Herb. Linn. No. 715.3 (LINN).
Current name: Ranunculus lingua L. (Ranunculaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 787, DOI: 10.5281/zenodo.291971
Extending high harmonic generation spectroscopy to new molecular species
Creators: name: McGrath, Felicity
Publisher: name: Imperial College London
Year: 2015

description: HHG spectroscopy is a powerful tool for observing electronic structure along with electronic and nuclear dynamics with state of the art resolution on the attosecond (10^−18 s = 1 as) timescale and angstrom (10^−10 m = 1 °A). Thus far, HHG spectroscopy has been applied to small hydrocarbons such as ethylene and methane using an 800 nm drive laser field wherein dynamics can only be measured in a 0.9 − 1.6 fs time window. This PhD has two primary aims: 1) to extend the time window over which we can make measurement up to 4 fs using an 2 μm drive laser field and 2) to perform HHG spectroscopy on molecules which are in the liquid phase at room temperature. The molecules at the focus of this thesis are benzene and substituted benzenes. The design and development of an apparatus to generate a stable vapour jet from a thin continuous nozzle is presented. The completed and tested apparatus has demonstrated that stable and reproducible spectra can be acquired with no contamination between different samples as they are switched over. Comparison of methylated benzene to benzene harmonic spectra show good agreement with theoretical results on coupled electron-nuclear dynamics developed by our collaborators. We also compare HHG spectra acquired under similar generating conditions from deuterated and protonated benzene which enables us to track nuclear dynamics and to determine the origin of the ionized electron in benzene. HHG spectra from the halogenated benzenes, in particular fluorobenzene, seem to illustrate the contribution of more tightly bound orbitals to the HHG signal which is indicative of dynamical interferences.
Deep Reinforcement Learning for Page-wise Recommendations
Creators: name: Zhao, Xiangyu
name: Xia, Long
name: Zhang, Liang
name: Ding, Zhuoye
name: Yin, Dawei
name: Tang, Jiliang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Recommender systems can mitigate the information overload problem by suggesting users' personalized items. In real-world recommendations such as e-commerce, a typical interaction between the system and its users is -- users are recommended a page of items and provide feedback; and then the system recommends a new page of items. To effectively capture such interaction for recommendations, we need to solve two key problems -- (1) how to update recommending strategy according to user's \textit{real-time feedback}, and 2) how to generate a page of items with proper display, which pose tremendous challenges to traditional recommender systems. In this paper, we study the problem of page-wise recommendations aiming to address aforementioned two challenges simultaneously. In particular, we propose a principled approach to jointly generate a set of complementary items and the corresponding strategy to display them in a 2-D page; and propose a novel page-wise recommendation framework based on deep reinforcement learning, DeepPage, which can optimize a page of items with proper display based on real-time feedback from users. The experimental results based on a real-world e-commerce dataset demonstrate the effectiveness of the proposed framework.
description: arXiv admin note: text overlap with arXiv:1802.06501
AMIGO
Creators: name: ARNAUD-HAOND Sophie
Publisher: name: Sismer
Year: 2017

description: En 2016, l'Ifremer a lancé le projet 'Pourquoi Pas les Abysses' (ABYSS) dans le cadre de l'opération MERLIN (pour la MER, Lancement d'Initiatives Nouvelles) qui, en partenariat national et international, permettra d'ouvrir des nouveaux fronts de recherche pour l'institut, en complément de ses travaux actuels. Le projet ABYSS repose sur le constat que beaucoup d'efforts sont encore nécessaires pour évaluer la richesse et la distribution mondiale de la biodiversité marine, y compris dans toute la plaine abyssale qui constitue le plus grand et moins étudié des écosystèmes sur terre. En mettant à profit les outils issus des Nouvelles Générations de Séquençage, ABYSS contribuera à une (re)évaluation de la biodiversité présente dans les abysses pour mieux comprendre son évolution et les facteurs environnementaux qui influencent sa distribution. L'ambition du projet ABYSS est de rassembler l'ensemble le plus représentatif possible d'échantillons à l'échelle mondiale, selon un schéma standardisé et répliqué, afin d'évaluer à la fois l'étendue et la nature de la biodiversité dans l'environnement profond sur l'ensemble de la planète. Afin d'atteindre cet objectif ambitieux, nous devions accéder à une diversité de zones géographiques nécessitant soit une circumnavigation dédiée (à l'instar des récentes expéditions Malaspina ou Tara), soit une optimisation de l'utilisation du temps de navire, en tirant parti des possibilités offertes par les campagnes déjà programmées et transits valorisables. C'est cette deuxième approche qui a été retenue et qui a fait l'objet de la proposition AMIGO, ce qui a permis une programmation AMIGO en 2017 et 2018 sur 3 transits valorisés et 7 campagnes 'amies' (ESSNAUT 2016, HERMINE, PEACETIME, ALPARRAY LEG1, BICOSE2, CHUBACARC, TONGA 2019).
Meson-meson correlations in baryon-baryon and antibaryon-baryon interactions
Creators: name: Holinde, K.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Recent work of the Jülich group about the role of meson-meson correlations in baryon-baryon and antibaryon-baryon interactions is reviewed.
description: Lecture given at the Erice School 1995, TEX, 10 pages, 15 figures
Github files
Creators: name: Kunze, Charlotte
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: R script and data used to quantify the net biodiversity effect in a phytoplankton microcosm experiment conducted in 2022 in the Planktotron mesocosm facility of the ICBM, University of Oldenburg.
Density Waves and the Viscous Overstability in Saturn's Rings
Creators: name: Lehmann, Marius
name: Schmidt, Juergen
name: Salo, Heikki
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: This paper addresses resonantly forced spiral density waves in a dense planetary ring which is close to the threshold for viscous overstability. We solve numerically the hydrodynamical equations for a dense, axisymmetric thin disk in the vicinity of an inner Lindblad resonance with a perturbing satellite. The spiral shape of a density wave is taken into account through a suitable approximation of the advective terms arising from the fluid orbital motion. This paper is a first attempt to model the co-existence of resonantly forced density waves and short-scale axisymmetric overstable wavetrains in Saturn's rings by conducting large-scale hydrodynamical integrations. These integrations reveal that the two wave types undergo complex interactions, not taken into account in existing models for the damping of density waves. In particular it is found that, depending on the relative magnitude of both wave types, the presence of viscous overstability can lead to a damping of an unstable density wave and vice versa. The damping of viscous overstability by a density wave is investigated further by employing a simplified model of an axisymmetric ring perturbed by a nearby Lindblad resonance. A linear hydrodynamic stability analysis as well as local N-body simulations of this model system are performed and support the results of our large-scale hydrodynamical integrations.
Reminiscences of Kenneth Claiborne Royall, 1963
Publisher: name: Columbia University
Year: 2021
Subjects: Lawyers
Government executives--United States
World War, 1939-1945
Korean War, 1950-1953
Nuremberg War Crime Trials, Nuremberg, Germany, 1946-1949
Presidents--Election--1948.--United States

description: Education; Harvard Law School and LAW REVIEW; German saboteurs case, 1942; head legal department, Fiscal Division of Army Service Forces, 1942-1943; Special Assistant to Secretary of War, 1944-1945; postwar congressional relations and investigating committees; Under Secretary of War, Secretaary of War, Secretary of Army, 1945-1949; unification of armed forces; 1948 Democratic presidential nomination; postwar crises: Turkey, Greece, Berlin blockade, Korea, Japan and Douglas MacArthur; integration efforts in Army; rejection of suggested appointment, Nuremberg trials. Impressions of Presidents Harry Truman and Dwight Eisenhower, Generals. George Marshall and James Van Fleet, Secretaries James Forrestal and Stuart Symington, others
Optical Identification of ROSAT sources in M 67: activity in an old cluster
Creators: name: Pasquini, L.
name: Belloni, T.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present optical identification and high-resolution spectroscopy of ROSAT sources in the field of the old open cluster M 67. For the first time it is possible to analyze coronal and chromospheric activity of active stars in a solar-age cluster, and to compare it with field stars. ROSAT observed the high X-ray luminosity tail of the cluster sources. In agreement with what expected from studies of field stars, most of the detected X-ray sources are binaries, preferably with short periods and eccentric orbits. In addition, several of the M 67 ROSAT sources have peculiar locations in the cluster colour-magnitude diagram. This is most likely due to rather complex evolutionary histories, involving the presence of mass transfer or large mass losses. The X-ray luminosity of the sources does not scale with the stellar parameters in an obvious way. In particular, no relationship is found between coronal emission and stellar magnitude or binary period. The Ca II K chromospheric flux from most of the counterparts is in excess to that of single stars in the cluster by one order of magnitude. The X-ray luminosity of the sources in the old M 67 is one order of magnitude lower than the most active active binaries in the field, but comparable to that of the much younger binaries in the Hyades.
description: 11 pages, 6 figures. Accepted for publication by Astronomy & Astrophysics
Additional file 1 of Local adaptive evolution of two distinct clades of Beijing and T families of Mycobacterium tuberculosis in Chongqing: a Bayesian population structure and phylogenetic study
Creators: name: Liang, Peng-Kuan
name: Zheng, Chao
name: Xu, Xiao-Fang
name: Zhao, Zhe-Ze
name: Zhao, Chang-Song
name: Li, Chang-He
name: Couvin, David
name: Reynaud, Yann
name: Zozio, Thierry
name: Rastogi, Nalin
name: Sun, Qun
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1 : Table S1. The source of available data in this study.
Ranunculus monspeliacus Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus monspeliacus

description: Ranunculus monspeliacus, spec. nov.
 24. Ranunculus foliis tripartitis crenatis, caule simplici villoso subnudo unifloro. Sauv. monsp. 181. †
 Ranunculus faxatilis, magno flore. Bauh. pin. 182. prodr. 96.
 Habitat Monspelii .
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 553, DOI: 10.5281/zenodo.3931989
Real-time Air Pollution prediction model based on Spatiotemporal Big data
Creators: name: Le, V. Duc
name: Cha, Sang Kyun
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computers and Society (cs.CY)
subject: Information Retrieval (cs.IR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Air pollution is one of the most concerns for urban areas. Many countries have constructed monitoring stations to hourly collect pollution values. Recently, there is a research in Daegu city, Korea for real-time air quality monitoring via sensors installed on taxis running across the whole city. The collected data is huge (1-second interval) and in both Spatial and Temporal format. In this paper, based on this spatiotemporal Big data, we propose a real-time air pollution prediction model based on Convolutional Neural Network (CNN) algorithm for image-like Spatial distribution of air pollution. Regarding to Temporal information in the data, we introduce a combination of a Long Short-Term Memory (LSTM) unit for time series data and a Neural Network model for other air pollution impact factors such as weather conditions to build a hybrid prediction model. This model is simple in architecture but still brings good prediction ability.
description: 6 pages
Ranunculus monspeliacus Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus monspeliacus

description: Ranunculus monspeliacus Linnaeus, Species Plantarum 1: 553. 1753.
"Habitat Monspelii." RCN: 4085.
Neotype (Baldini in Jarvis & al. in Taxon 54: 470. 2005): France. Narbonne (Aude), Jun 1874, ex Herb. R.P. Murray, Boutigny s.n. (BM).
Current name: Ranunculus monspeliacus L. (Ranunculaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 787, DOI: 10.5281/zenodo.291971
Quantized Nonlinear Gaussian-Beam Dynamics $-$ Tailoring Multimode Squeezed-Light Generation
Creators: name: Lanning, R. Nicholas
name: Xiao, Zhihao
name: Zhang, Mi
name: Novikova, Irina
name: Mikhailov, Eugeniy E.
name: Dowling, Jonathan P.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We present a general, second quantization procedure for multi-transverse-spatial mode Gaussian beam dynamics in nonlinear interactions. Previous treatments have focused on the spectral density and angular distribution of spatial modes. Here we go a layer deeper by investigating the complex transverse-spatial mode in each angular-spatial mode. Furthermore, to implement the theory, we simulate four-wave mixing and parametric down-conversion schemes, showing how one can elucidate and tailor the underlying multi-transverse-spatial mode structure along with it's quantum properties.
Ranunculus muricatus Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus muricatus

description: Ranunculus muricatus, spec. nov.
 32. Ranunculus seminibus aculeatis, foliis simplicibus palmatis incisis. Hort. cliff. 229. Hort. ups. 157. Roy. lugdb. 491. Sauv. monsp. 204.
 Ranunculus palustris echinatus. Bauh. pin. 180. prodr. 95.
 β. Ranunculus rotundifolius repens echinatus. Bauh. pin. 180. prodr.95.
 γ. Ranunculus stellatus echinatus creticus. Bauh. pin. 180.
 δ. Ranunculus hirsutus annuus, flore minimo. Raj. angl. 3. p.248. t.12. f.1. Pluk. alm. 311. t.55. f.1.
 Ranunculus arvensis annuus hirsutus, flore omnium minimo. Moris. hist. 2. p.440. s.4. t.28. f.21.
 Habitat in Europae australis fossis & humentibus. ☉
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 555, DOI: 10.5281/zenodo.3931989
Role of the type II diabetes-associated gene SLC30A8 in the pancreatic α-cell
Creators: name: Solomou, Antonia
Publisher: name: Imperial College London
Year: 2015

description: The SLC30A8 locus encodes the Zn2+ transporter ZnT8, whose expression is largely restricted to α- and β-cells, endocrine cells of the pancreatic islet. Genome-wide association studies have revealed >90 loci associated with Type 2 diabetes. The first such study identified a specific single nucleotide polymorphism that results in an amino acid substitution and a transporter with reduced activity. This risk variant is associated with increased Type 2 diabetes risk. More recently, rare loss-of-function variants were found to be protective. Here, we aimed to investigate the role of SLC30A8/ZnT8 in the regulation of glucagon secretion. ZnT8 was selectively deleted in the α-cell by crossing mice bearing floxed alleles at exon 1 with mice carrying a Cre recombinase transgene under the control of the preproglucagon promoter. Additionally, these mice were crossed to Rosa26 RFP mice for identification of α-cells. Fluorescence-activated sorting of RFP+ cells revealed that recombination at the RFP locus occurred in ~30% of α-cells. ZnT8 was deleted in ~50% of these labelled cells achieving a total of ~15% deletion in the whole α-cell population. Glucose tolerance and insulin sensitivity were normal, though during hypoglycaemic clamps female KO mice required lower glucose infusion rates and had enhanced glucagon secretion compared to control mice. Similarly, isolated islets from KO mice released significantly more glucagon at 1mM glucose. In addition, inducible overexpression of ZnT8 led to a reciprocal decrease of glucagon secretion from isolated islets at 1mM glucose. Hypoglycaemic clamps confirmed the finding of lowered glucagon release following ZnT8 overexpression. Cytosolic Ca2+ responses to low glucose were comparable in WT and KO cells. Both cytoplasmic and granular free Zn2+ levels were significantly reduced in the KO α-cells compared to control cells yet there were no changes in the gene expression levels of other ZnT famlily members. Thus it appears that ZnT8 is important in the α-cell for appropriate responses to hypoglycaemia and Zn2+ homeostasis.
Pulsed coherent drive in the Jaynes--Cummings model
Creators: name: Fischer, Kevin
name: Sun, Shuo
name: Lukin, Daniil
name: Kelaita, Yousif
name: Trivedi, Rahul
name: Vučković, Jelena
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The Jaynes--Cummings system is one of the most fundamental models of how light and matter interact. When driving the system with a coherent state (e.g. laser light), it is often assumed that whether the light couples through the cavity or atom plays an important role in determining the dynamics of the system and its emitted field. Here, we prove that the dynamics are identical in either case except for the offset of a trivial coherent state. In particular, our formalism allows for both steady-state and the treatment of any arbitrary multimode coherent state driving the system. Finally, the offset coherent state can be interferometrically canceled by appropriately homodyning the emitted light, which is especially important for nanocavity quantum electrodynamics where driving the atom is much more difficult than driving the cavity.
CHEREEF-OBS
Creators: name: MENOT Lenaick
Publisher: name: Sismer
Year: 2021

description: L'objectif de la série de campagnes ChEReef-OBS est de décrire et comprendre la dynamique des habitats benthiques et en particulier des récifs de coraux d'eau froide dans les canyons du golfe de Gascogne : notamment comprendre la distribution des habitats coralliens à l'échelle d'un canyon et comprendre la dynamique temporelle des espèces ingénieures qui structurent ces habitats. L'objectif sera également de mieux comprendre le rôle des facteurs géomorphologiques, hydrodynamiques, sédimentaires et anthropiques dans la distribution des habitats récifs dans les canyons.Dans cette optique, un observatoire autonome sera déployé jusqu'en 2025 sur un récif de coraux, à environ 1000m de profondeur. Les données de l'observatoire seront complétées par des approches multidisciplinaires et multi-échelles visant à modéliser les processus hydrodynamiques, comprendre la dynamique sédimentaire, cartographier et suivre l'évolution des habitats benthiques du canyon et leur faune associée, décrire et quantifier la croissance, le métabolisme et le comportement des coraux récifaux en conditions naturelles et en conditions contrôlées.
Ranunculus muricatus Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Ranunculales
Ranunculaceae
Ranunculus
Ranunculus muricatus

description: Ranunculus muricatus Linnaeus, Species Plantarum 1: 555. 1753.
"Habitat in Europae australis fossis & humentibus." RCN: 4094.
Lectotype (Lourteig in Darwiniana 9: 487. 1951): Herb. Linn. No. 715.66 (LINN).
Current name: Ranunculus muricatus L. (Ranunculaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 787, DOI: 10.5281/zenodo.291971
Additional file 6 of Functional MYB transcription factor gene HtMYB2 is associated with anthocyanin biosynthesis in Helianthus tuberosus L
Creators: name: Gao, Jieming
name: Sun, Xuemei
name: Zong, Yuan
name: Yang, Shipeng
name: Wang, Lihui
name: Liu, Baolong
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 6: Table S5. Oligo nucleotide primers used in this work.
The role of emerin in the pathogenesis of sporadic inclusion body myositis
Creators: name: Marini Bettolo, Chiara
Publisher: name: Imperial College London
Year: 2015

description: Idiopathic Inflammatory Myopathies (IIMs) are a heterogeneous group of acquired diseases characterised by inflammation of the skeletal muscle. The most common forms are sporadic inclusion body myositis (sIBM), dermatomyositis, polymyositis, overlap syndormes and necrotising myopathy. Sporadic IBM is the most common acquired myopathy over the age of 50 years, however its pathogenesis remains largely unsolved and there is still debate on whether it is a primary inflammatory or a degenerative condition with secondary inflammatory component. I used an in silico approach to identify molecules of interest that might shed light on the pathogenesis of sIBM. Emerin, a nuclear envelope protein, resulted as one of the candidate molecules. To verify in silico analysis results I reviewed a cohort of patients with sIBM phenotype identified at Charing Cross Hospital. This review allowed me to select 10 sIBM patients and identify 3 further patients with sIBM-like phenotype and good response to steroids. The selected patients have been then tested through immunohistochemical, immunoblotting and sequencing studies. Immunohistochemistry studies using anti-emerin antibodies showed abnormal distribution of emerin in the sIBM patients but not in the 3 patients with sIBM-like phenotype. Interestingly, sequencing of the emerin gene identified missense mutations in the 5’-untranslated region. The three IBM-like patients were extensively studied and serum analysis allowed me to identify a novel autoantibody that proved to target the sarcoglycans. Sequencing of the sarcoglycans genes in the three patients identified a missense mutation in the β-sarcoglycan affecting the 3D-structure of the extracellular component. The identification of this novel autoantibody prompted a further pilot study to develop a diagnostic test to identify novel autoantibodies to sarcolemmal proteins. Variable positive reactivity against sarcolemmal proteins, suggestive of presence of autoantibodies against sarcolemmal proteins was identified through immunoblotting in the sera of 10 further IIM patients, but not in 9 controls. This study highlights the complexity behind the pathogenesis of IIM and importance of unified classification criteria. Although further studies on a larger scale will be needed I suggest that emerin immunolabeling could be used as diagnostic biomarker in patients with sIBM. In addition, a pilot study using of skeletal muscle protein extract revealed novel autoantibodies in IIM whose pathogenicity remains to be established.
Gluon propagator on a centre-vortex background
Creators: name: Biddle, James C.
name: Kamleh, Waseem
name: Leinweber, Derek B.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The impact of $SU(3)$ centre vortices on the gluon propagator in Landau gauge is investigated on original, vortex-removed and vortex-only lattice gauge field configurations. Vortex identification is found to partition the gluon propagator into short range strength on the vortex removed configurations and long range strength on the vortex only configurations. The effect of smoothing vortex-only configurations is also studied, and a regime for recovering the form of the smoothed original propagator from vortex-only configurations is introduced. The results reinforce the significance of centre vortices in a fundamental understanding of QCD vacuum structure.
description: 9 pages, 9 figures, 1 table, version accepted for publication
New thiophene based semi-conducting materials for applications in plastic electronics
Creators: name: Schroeder, Bob
Publisher: name: Imperial College London
Year: 2013

description: Organic semiconductors have several advantages over inorganic ones, such as their cheap solution processability and their tolerance for flexible substrates. On the other hand organic semiconductors are still lacking the performance of inorganics, which makes the large scale commercialisation challenging. This work focuses on synthesizing new fused thiophene based donor moieties and their subsequent incorporation into semiconducting polymers. At first the synthesis of the benzotrithiophene (BTT) chromophore was attempted. The large aromatic unit has a strong tendency to aggregate and its incorporation into semiconducting polymers, resulted initially in insoluble material. However by carefully adjusting the solubilising side chains on the BTT core and by judiciously choosing the electron accepting comonomer, it was possible to synthesize highly soluble polymers, both for organic field effect transistors (OFET) and organic photovoltaics (OPV). When designing the polymers for OFET applications, extra care was taken to minimize backbone bending, thus allowing high charge carrier mobilities of 0.22 cm²/Vs. A similarly good performance was achieved in solar cells when BTT containing low bandgap polymers where employed, increasing the efficiency from initially 1.4% to promising 5%, and this without the use of processing additives. A second part of this work focuses on the synthesis of extended π-conjugated ladder type monomers, which present many desirable features for optoelectronical applications. Two classes of such polymers will be synthesized, silaindacenodithiophene (SiIDT), respectively thieno[3,2-b]thienobis(silolothiophene) (Si4T) containing polymers. Overall thirteen different polymers were obtained with those new donor units, which allowed an extensive study of various parameters on polymer thin film morphology and the effects on device performance. By systematically adjusting the polymer’s energy levels, solubilising alkyl side chains and aromatic building blocks, it was possible to achieve power conversion efficiencies in excess of 6% in organic solar cells and hole mobilities of ~0.3 cm2/Vs in OFET devices. Furthermore this series of polymers was the ideal platform to investigate the influence of polymer purity on device performance, which is of great importance to industry, because it would potentially eliminate any batch-to-batch variation making the production more reproducible and reliable. According to our findings, polymer purity is a key requirement for high performing devices because the solar cell efficiencies could be increased by 30% after material purification.
Structure-sensitive Multi-scale Deep Neural Network for Low-Dose CT Denoising
Creators: name: You, Chenyu
name: Yang, Qingsong
name: Shan, Hongming
name: Gjesteby, Lars
name: Li, Guang
name: Ju, Shenghong
name: Zhang, Zhuiyang
name: Zhao, Zhen
name: Zhang, Yi
name: Cong, Wenxiang
name: Wang, Ge
Publisher: name: arXiv
Year: 2018
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Computed tomography (CT) is a popular medical imaging modality in clinical applications. At the same time, the x-ray radiation dose associated with CT scans raises public concerns due to its potential risks to the patients. Over the past years, major efforts have been dedicated to the development of Low-Dose CT (LDCT) methods. However, the radiation dose reduction compromises the signal-to-noise ratio (SNR), leading to strong noise and artifacts that down-grade CT image quality. In this paper, we propose a novel 3D noise reduction method, called Structure-sensitive Multi-scale Generative Adversarial Net (SMGAN), to improve the LDCT image quality. Specifically, we incorporate three-dimensional (3D) volumetric information to improve the image quality. Also, different loss functions for training denoising models are investigated. Experiments show that the proposed method can effectively preserve structural and texture information from normal-dose CT (NDCT) images, and significantly suppress noise and artifacts. Qualitative visual assessments by three experienced radiologists demonstrate that the proposed method retrieves more detailed information, and outperforms competing methods.
description: IEEE Access 2018
The determinants of the excess risk of type-2 diabetes amongst Indian Asians compared to Europeans
Creators: name: Sehmi, Jobanpreet Singh
Publisher: name: Imperial College London
Year: 2013

description: Background Indian Asians are at increased risk of type-2 diabetes (T2D), insulin resistance and related metabolic disturbances compared to Europeans. The contribution of known lifestyle and genetic risk factors to the excess risk of T2D in Indian Asians is not well understood. Methods and materials I investigated 16,774 Indian Asian and 7,301 European men and women participating in the in the London Life Sciences Population Study to determine the prevalence of T2D and related glycaemic disorders. I examined the contribution of adiposity, leisure time physical activity, major dietary macronutrients and known genetic susceptibility factors to the increased risk of T2D and related metabolic disturbances amongst Indian Asians compared to Europeans. Lastly I carried out a genome-wide association and replication study amongst 58,687 Indian Asian participants to identify novel genetic factors in this ethnic group. Results The prevalence of T2D is ~4-fold higher amongst Indian Asians than Europeans, and is not accounted for by differences in adiposity and leisure time physical activity. In dietary studies, intake of fibre is inversely related to risk of insulin resistance among Indian Asians. However, major dietary macronutrients do not account for differences in insulin resistance between Indian Asians and Europeans. In genetic studies I demonstrate association of 25 previously reported T2D genetic variants with T2D amongst Indian Asians. Of the 48 T2D genetic variants examined, risk allele frequencies were similar and effect sizes lower amongst Indian Asians compared to Europeans; therefore known T2D genetic variants do not account for the increased risk of T2D in this racial group. In the GWAS I discover 6 novel T2D genetic variants among Indian Asians (GRB14, ST6GAL1, VPS26A, HMG20A, AP3S2 and HNF4A). Conclusions T2D has emerged as a major healthcare problem worldwide, with rates highest among individuals of Indian Asian descent. For the first time I discover six novel genetic susceptibility factors for T2D amongst Indian Asians. However, there is a ~4-fold higher risk of T2D among Indian Asians compared to Europeans, which remains largely unexplained.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Cart. 192 (11 H 77), 295 folios, f. 0120r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0120r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0120r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Room temperature deformation in the Fe$_7$Mo$_6$ $μ$-Phase
Creators: name: Schröders, Sebastian
name: Sandlöbes, Stefanie
name: Birke, Carola
name: Loeck, Matthias
name: Peters, Lars
name: Tromas, Christophe
name: Korte-Kerzel, Sandra
Publisher: name: arXiv
Year: 2018
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The role of TCP phases in deformation of superalloys and steels is still not fully resolved. In particular, the intrinsic deformation mechanisms of these phases are largely unknown including the active slip systems in most of these complex crystal structures. Here, we present a first detailed investigation of the mechanical properties of the Fe7Mo6 μ-phase at room temperature using microcompression and nanoindentation with statistical EBSD-assisted slip trace analysis and TEM imaging. Slip occurs predominantly on the basal and prismatic planes, resulting also in decohesion on prismatic planes with high defect density. The correlation of the deformation structures and measured hardness reveals pronounced hardening where interaction of slip planes occurs and prevalent deformation at pre-existing defects.
description: Accepted manuscript in International Journal of Plasticity
Microscopic Structure of High-Spin Vibrational Excitations in Superdeformed 190,192,194Hg
Creators: name: Nakatsukasa, Takashi
name: Matsuyanagi, Kenichi
name: Mizutori, Shoujirou
name: Shimizu, Yoshifumi R.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Microscopic RPA calculations based on the cranked shell model are performed to investigate the quadrupole and octupole correlations for excited superdeformed bands in 190Hg, 192Hg, and 194Hg. The K=2 octupole vibrations are predicted to be the lowest excitation modes at zero rotational frequency. At finite frequency, however, the interplay between rotation and vibrations produces different effects depending on neutron number: The lowest octupole phonon is rotationally aligned in 190Hg, is crossed by the aligned two-quasiparticle bands in 192Hg, and retains the K=2 octupole vibrational character up to the highest frequency in 194Hg. The gamma vibrations are predicted to be higher in energy and less collective than the octupole vibrations. From a comparison with the experimental dynamic moments of inertia, a new interpretation of the observed excited bands invoking the K=2 octupole vibrations is proposed, which suggests those octupole vibrations may be prevalent in SD Hg nuclei.
description: 22 pages, REVTeX, 12 postscript figures are available on request
title: Exploring novel functionalities in oxide ion conductors with excess oxygen
Creators: name: Zhang, Yaoqing
Publisher: name: University of St Andrews
publisherIdentifier: https://ror.org/02wn5qz54
publisherIdentifierScheme: ROR
Year: 2011

description: Functional materials, particularly metal oxides, have been the focus of much attention in solid state chemistry for many years and impact every aspect of modern life. The approach adopted in this thesis to access desirable functionality for enhanced fundamental understanding is via modifying existing materials by deploying reducing synthetic procedures. This work spans several groups of inorganic crystalline materials, but is unified by the development of new properties within host compounds of particular relevance to solid oxide fuel cell technology, which allow interstitial oxide ion conduction at elevated temperatures. The Ca₁₂Al₁₄O₃₂e₂ electride was successfully synthesized by replacing the mobile extra-framework oxygen ions with electrons acting as anions. The high concentration of electrons in the C12A7 electride gives rise to an exceptionally high electronic conductivity of up to 245 S cm⁻¹ at room temperature. Making use of the high density of electrons in Ca₁₂Al₁₄O₃₂e₂ electride, the strong N-N bonds in N₂ was found to be broken when heating Ca₁₂Al₁₄O₃₂e₂ in a N₂ atmosphere. A reaction between silicate apatites and the titanium metal yielded another completely new electride material La₉.₀Sr₁.₀(SiO₄)₆O₂.₄e₀.₂ which was found to be a semiconductor. To fully understand the role of oxygen interstitials in silicate apatites, high-resolution transmission electron microscopy (HRTEM) was employed as the main technique in probing how the oxygen nonstoichiometry is accommodated at the atomic level. Atomic-resolution imaging of interstitial oxygen in La₉.₀Sr₁.₀(SiO₄)₆O₂.₅ proved to be a success in this thesis. Substitution of oxygen in 2a and interstitial sites with fluoride ions in La[subscript(8+y)]Sr[subscript(2- z)](SiO₄)₆O[subscript(2+(3y-2z)/2)] (0<y<2, 0<z<2) could be an approach to enriching the functionalities in the apatite structure. A wide range of fluoride substitution levels was tolerated in La[subscript(10-x)]Sr[subscript(x)](SiO₄)₆O[subscript(3-1.5x)]F[subscript(2x)] (x= 0.67, 1, 1.5, 2) and AC impedance measurements were found in support of a tentative conclusion that fluoride ions could be mobile in fluorinated apatites. The last part of this thesis was focused on a new class of fast oxide ion conductors based on Ge₅P₆O₂₅ whose performance was superior to both La₉.₀Sr₁.₀(SiO₄)₆O₂.₅ and Ca₁₂Al₁₄O₃₃ in the low temperature range.
On the Staggering Effect of Dynamical Moments of Inertia in Superdeformed Bands
Creators: name: Magierski, P.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The possibility of the appearance of the C$_{4}$ symmetry in the rotational bands is studied within the particle-rotor model. Allowing for a slight triaxiality of the rotor it is shown that the lowest states of the system for a sufficiently high spin possess the symmetry which allows to distinguish states differing by two units of angular momentum.
description: REVTeX file, 6 pages, 2 figures (available as postscript files upon request to magiersk@dingo.if.pw.edu.pl), to appear in Acta Phys. Pol. B