cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Herpetocythere acanthoides Hart & Hart 1967, sp. nov.
Creators: name: Williams, Bronwyn W.
name: Weaver, Patricia G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Ostracoda
Herpetocythere
Herpetocythere acanthoides

description: Herpetocythere acanthoides Hart & Hart, 1967
1967b Herpetocythere acanthoides sp. nov. —Hart & Hart: 8, 23, 24, 44, 45, Figs. 61–62 (A, D, H, K, M, T).
1974 Herpetocythere acanthoides Hart and Hart, 1967.—Hart & Hart: 145, 149, 215, 236, Pl. XXXIX Figs. 13–14, Pl. LX (C, D, H, K, T).
1975 Herpetocythere acanthoides Hart & Hart, 1967.—Hart & Hart: 55 (C, D, H).
1977 Herpetocythere acanthacoides Hart & Hart. —Suter & Richardson: 100, 102 [by implication], erroneous spelling (D, E, H).
2014a Herpetocythere acanthoides Hart & Hart, 1967.—Mestre, Monrós & Mesquita-Joanes: 950 (C).
description: Published as part of Williams, Bronwyn W. & Weaver, Patricia G., 2018, A historical review of the taxonomy and classification of Entocytheridae (Crustacea: Ostracoda: Podocopida), pp. 1-129 in Zootaxa 4448 (1) on pages 100-101, DOI: 10.11646/zootaxa.4448.1.1, http://zenodo.org/record/1444492
Effectiveness of standard and alternative design septic systems in renovating domestic wastewater in Pinelands soils
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1986

description: The objectives of this study are to: 1. determine the relationships between nutrient concentrations of effluent and leachate in individual on-site wastewater disposal systems of various designs utilized in the Pinelands; and 2. test the validity of certain assumptions used to predict the impact of on-site wastewater disposal systems on ground-water quality in the Pinelands.
Scissurellidae
Creators: name: Leal, José H.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Lepetellida
Scissurellidae

description: Family Scissurellidae
Sinezona redferni Rolán, 1996; eight paratypes.
description: Published as part of Leal, José H., 2021, Type specimens in the molluscan collection of the Bailey-Matthews National Shell Museum, Florida, USA, pp. 1-40 in Zootaxa 4951 (1) on page 3, DOI: 10.11646/zootaxa.4951.1.1, http://zenodo.org/record/4655535
Chinese Herb/Chemotherapy Interactions in Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Traditional Chinese Medicine (TCM) is a treatment modality that has been used for centuries to treat cancer, prolong life, and increase the quality of life for cancer patients. The lack of evidence-based clinical trials coupled with the proliferation of anecdotal and case report studies of TCM make it an important treatment modality to study. TCM use in the San Francisco Bay Area is widespread and frequently used by our patient population, thus it can be studied using standard research models at our institution. There is a high degree of conformity among TCM practitioners in terms of diagnoses and treatments due to the extensive historically-based documentation of TCM treatment modalities.

 We have recently obtained laboratory data on the effects of over 70 Chinese herbal extracts on the growth of breast cancer cells in culture. These herbs have been traditionally prescribed by TCM practitioners for metastatic breast cancer and other cancer patients. Many of these herbal extracts demonstrated significant inhibitory effects in our initial screening. Since many cancer patients who take these herbs also receive conventional chemotherapy, the objective of this project is to determine what kinds of interactions these herbs have with standard chemotherapeutic agents.

 Herbs will be prepared as boiled teas, as they are traditionally prepared. Breast cancer cells growing in tissue culture will be treated with individual herbs, chemotherapeutic drugs, or combinations of an herb with a chemotherapeutic drug. After three days of treatment, the cells will be analyzed for growth/death. Growth curves will be generated from these data and comparisons of the curves from individual herbs, drugs, and their combinations will determine whether the herbs act to enhance the effects of the drugs, inhibit their effects, or have no effect. We will then examine the effects of herb/drug combinations that show greater activity than either alone in a mouse model of breast cancer.

 Rather than randomly screening thousands of plants for anti-breast cancer activity, we have focused on plants which have been used for hundreds/thousands of years in Chinese medicine. In addition, we are administering these agents as “teas” which is how they are traditionally administered to patients.
Herpetocythere australensis Hart & Hart 1967, sp. nov.
Creators: name: Williams, Bronwyn W.
name: Weaver, Patricia G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Ostracoda
Herpetocythere
Herpetocythere australensis

description: * Herpetocythere australensis Hart & Hart, 1967
1967b Herpetocythere australensis sp. nov. —Hart & Hart: 6, 8, 18–19, 20, 21, 22, 26, 40, 41, Figs. 42–47 (A, D, H K, R, T).
1974 Herpetocythere australensis Hart and Hart, 1967.—Hart & Hart: 146, 148, 149, 150, 151, 215, 236, Pl. XXXIX Figs. 15–17, Pl. LX (C, D, H, K, R, T).
1975 Herpetocythere australensis Hart & Hart, 1967.—Hart & Hart: 55–56 (C, D, H).
2014a Herpetocythere australensis Hart & Hart, 1967.—Mestre, Monrós & Mesquita-Joanes: 950 (C).
description: Published as part of Williams, Bronwyn W. & Weaver, Patricia G., 2018, A historical review of the taxonomy and classification of Entocytheridae (Crustacea: Ostracoda: Podocopida), pp. 1-129 in Zootaxa 4448 (1) on page 101, DOI: 10.11646/zootaxa.4448.1.1, http://zenodo.org/record/1444492
Elasmus viridiceps Thomson
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 34. Elasmus viridiceps Thomson
Material examined. See Yefremova & Strakhova (2012).
Hosts. Ectoparasitoid of Bethylidae (Hymenoptera) (Strakhova et al. 2011). Distribution. Israel (Yefremova & Strakhova 2012); Palearctic (Graham 1995; Yefremova & Strakhova, 2010).
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on page 10, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546
Somerset County, New Jersey area wide TOPICS study: Part IV - Bound Brook, Bridgewater, Franklin, Manville, Raritan, South Bound Brook
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1972

description: TOPICS, the acronym for "Traffic Operations Program to Increase Capacity and Safety", was a program designed to effectively channel Highway Trust funds into the revitalization of traffic networks in urban areas. This study evaluated the efficiency of the existing network of streets and highways in fulfilling the community's transportation requirements.
Somerset County, New Jersey area wide TOPICS study: Part III - Greenbrook, North Plainfield, Watchung
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1972

description: TOPICS, the acronym for "Traffic Operations Program to Increase Capacity and Safety", was a program designed to effectively channel Highway Trust funds into the revitalization of traffic networks in urban areas. This study evaluated the efficiency of the existing network of streets and highways in fulfilling the community's transportation requirements.
Somerset County, New Jersey area wide TOPICS study: Part I - Somerville
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1972

description: TOPICS, the acronym for "Traffic Operations Program to Increase Capacity and Safety", was a program designed to effectively channel Highway Trust funds into the revitalization of traffic networks in urban areas. This study evaluated the efficiency of the existing network of streets and highways in fulfilling the community's transportation requirements.
Somerset County, New Jersey area wide TOPICS study: Part II - Bernards, Bernardsville
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1972

description: TOPICS, the acronym for "Traffic Operations Program to Increase Capacity and Safety", was a program designed to effectively channel Highway Trust funds into the revitalization of traffic networks in urban areas. This study evaluated the efficiency of the existing network of streets and highways in fulfilling the community's transportation requirements.
Skeneidae
Creators: name: Leal, José H.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Trochida
Skeneidae

description: Family Skeneidae
Haplocochlias minusdentatus Rubio, Rolán, & Redfern, 2013 (Figure 3); one paratype.
description: Published as part of Leal, José H., 2021, Type specimens in the molluscan collection of the Bailey-Matthews National Shell Museum, Florida, USA, pp. 1-40 in Zootaxa 4951 (1) on page 3, DOI: 10.11646/zootaxa.4951.1.1, http://zenodo.org/record/4655535
Inferring Skin-Brain-Skin Connections from Infodemiology Data using Dynamic Bayesian Networks
Creators: name: Scutari, Marco
name: Kerob, Delphine
name: Salah, Samir
Publisher: name: arXiv
Year: 2024
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: The relationship between skin diseases and mental illnesses has been extensively studied using cross-sectional epidemiological data. Typically, such data can only measure association (rather than causation) and include only a subset of the diseases we may be interested in. In this paper, we complement the evidence from such analyses by learning an overarching causal network model over twelve health conditions from the Google Search Trends Symptoms public data set.
 We learned the causal network model using a dynamic Bayesian network, which can represent both cyclic and acyclic causal relationships, is easy to interpret and accounts for the spatio-temporal trends in the data in a probabilistically rigorous way. The causal network confirms a large number of cyclic relationships between the selected health conditions and the interplay between skin and mental diseases. For acne, we observe a cyclic relationship with anxiety and attention deficit hyperactivity disorder (ADHD) and an indirect relationship with depression through sleep disorders. For dermatitis, we observe directed links to anxiety, depression and sleep disorders and a cyclic relationship with ADHD. We also observe a link between dermatitis and ADHD and a cyclic relationship between acne and ADHD. Furthermore, the network includes several direct connections between sleep disorders and other health conditions, highlighting the impact of the former on the overall health and well-being of the patient.
 Mapping disease interplay, indirect relationships, and the key role of mediators, such as sleep disorders, will allow healthcare professionals to address disease management holistically and more effectively. Even if we consider all skin and mental diseases jointly, each disease subnetwork is unique, allowing for more targeted interventions.
description: 14 pages, 3 figures
Physical skill learning increases neurogenesis through cell survival in the hippocampus
Creators: name: Curlik,
Publisher: name: No Publisher Supplied
Year: 2012

description: The dentate gyrus is a major site of plasticity in the adult brain, giving rise to thousands of new neurons every day. While the majority of these cells die within two weeks of their birth, they can be rescued from death by various forms of learning. The successful acquisition of select types of associative and spatial memories can increase the number of these cells that survive. Here, we investigated the possibility that an entirely different form of learning, physical skill learning, could rescue these new neurons from death. To test this possibility, rats were trained with a physically-demanding and technically-difficult version of a rotarod procedure. Acquisition of the physical skill greatly increased the number of new hippocampal cells that survived. The number of surviving cells positively correlated with performance on the task. Only animals that successfully learned the task retained the cells that would have otherwise died. Animals that failed to learn, and those that did not learn well, did not retain any more cells than those that were untrained. Importantly, acute voluntary exercise in activity wheels did not increase the number of surviving cells. These data indicate that skill learning, and not physical activity per se, increased the number of surviving cells. Moreover, learning an easier version of the task did not increase cell survival. These data are consistent with previous studies revealing that learning rescues new neurons from death, but only when acquisition is sufficiently difficult to achieve. Finally, complete hippocampal lesions did not disrupt acquisition of this physical skill. Therefore, learning this motor skill task does not depend on the hippocampus, even though it can increase the number of surviving cells in the structure. These data, and their implications, suggest that humans who learn new and complicated sports or other physical skills will retain more new neurons than humans that do not engage in effortful activities.
Herpetocythere bendora Hart & Hart 1967, sp. nov.
Creators: name: Williams, Bronwyn W.
name: Weaver, Patricia G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Ostracoda
Herpetocythere
Herpetocythere bendora

description: Herpetocythere bendora Hart & Hart, 1967
1967b Herpetocythere bendora sp. nov. —Hart & Hart: 8, 15, 19, 20–21, 42, 43, Figs. 50–53 (A, D, H, K, R, T).
1974 Herpetocythere bendora Hart and Hart, 1967.—Hart & Hart: 146, 149–150, 215, 236, Pl. XXXIX Figs. 18– 19, Pl. LX (C, D, H, K, R, T).
1975 Herpetocythere bendora Hart & Hart, 1967.—Hart & Hart: 56 (C, D, H).
2014a Herpetocythere bendora Hart & Hart, 1967.—Mestre, Monrós & Mesquita-Joanes: 950 (C).
description: Published as part of Williams, Bronwyn W. & Weaver, Patricia G., 2018, A historical review of the taxonomy and classification of Entocytheridae (Crustacea: Ostracoda: Podocopida), pp. 1-129 in Zootaxa 4448 (1) on page 101, DOI: 10.11646/zootaxa.4448.1.1, http://zenodo.org/record/1444492
The information use behaviors of graduate students in an online learning community
Creators: name: Cooke, Nicole Amy
Publisher: name: No Publisher Supplied
Year: 2012

description: As online education expands, research should identify how students interact and learn  online. Because of the technological, proximal and asynchronous uniqueness of online  education, learners face challenges not native to face-to-face education. As such, online  students may seek alternate relationships and methods of interacting, forming their own “Small  Worlds.” Online students have their own “view of social reality, and ways in which they satisfy  their intellectual, social, and physical needs” (Chatman, 1991, p. 438). Small Worlds allow  people “to share a similar cultural and intellectual space” (Huotari & Chatman, 2001, p. 352),  and members “share a repertoire of resources and sensibilities communally developed over  time” (Wenger, 1998, p. 2). Chatman’s theory of Small Worlds is a spatial and social lens  through which to examine information behavior; in this instance the online learning  environment is a virtual space that fosters and shapes the information behaviors of its  participants.    The purpose of this study was to investigate the information use behaviors of graduate  students in an online learning community, and to elucidate the information interactions and  exchanges that occur within course threaded discussions. Additionally, this study intended to  determine if and how graduate students in Library and Information Science programs created  community in the online classroom, and how, if at all, the presence of community influenced  information use behaviors.    With respect to the learning online, the literature clearly addresses distance education,  Internet communities, communities of practice, and the development of community in  traditional on campus classrooms. Some of this research begins to encompass various aspects of  human information behavior as applied to the online setting. However, the literature does not  marry these components and does not examine nor address the specific information needs and  dynamics that occur in an online graduate classroom. The goal of this research was to provide a  detailed analysis of the nature and dynamics of information behaviors in an asynchronous  graduate online classroom, to identify factors that shape these behaviors, and to determine  their relationship to the process of knowledge construction.
Electronic structure and binding geometry of tetraphenylporphyrin-derived molecules adsorbed on metal and metal oxide surfaces
Creators: name: Coh, Senia
Publisher: name: No Publisher Supplied
Year: 2012

description: Tetraphenylporphyrin (TPP)-derived molecules have been  studied extensively as efficient photosensitizers when chemisorbed  on the metal oxide substrates in dye-sensitized solar cells. Still,  many fundamental electronic properties of the dye/oxide interface  are not understood and need careful consideration. In this thesis we  present a comprehensive study of the electronic structure, energy  level alignment and the adsorption geometry of the TPP-derived dye  molecules adsorbed on TiO$_2$(110), ZnO(11$overline{2}$0) and  Ag(100) single crystal surfaces using ultra-high vacuum (UHV) based  surface sensitive techniques.    The alignment of the molecular energy levels with respect to the  TiO$_2$ and ZnO band edges for all TPP-derived molecules we studied  was found to be insensitive to either the nature of the functional  groups located on the phenyl rings, presence of zinc as a central  metal ion and different binding geometry of the molecules. Binding  geometry, molecule-molecule interaction and the aggregation effects  in the adsorbed layer, that were observed in the UV-visible spectra  of the molecules adsorbed on ZnO substrate were not observed in the  ultraviolet photoemission (UPS) and inverse photoemission (IPS)  spectra of the occupied and unoccupied molecular states. Using near  edge X-ray absorption fine structure (NEXAFS) and scanning tunneling  microscopy (STM), binding geometry of the two representative  TPP-derivatives was directly determined to be upright, with the  porphyrin ring under large angle with respect to the surface for the  emph{p}-ZnTCPP molecules and with the porphyrin ring parallel to  the surface for the emph{m}-ZnTCPP molecules.    We observe that the energies and the energy level alignment of the  ZnTPP molecular levels measured in UPS and IPS depend on the  substrate on which the molecules are adsorbed (Ag(100) or  TiO$_2$(110) single crystal surfaces). The differences are  attributed to different charge screening properties of these two  materials. Image charges created in the substrates during the  measurement affect both the ground state electronic structure and  the electronic excitations in the molecules causing the transport  gap, the optical gap and the exciton binding energy of the molecules  to decrease as the thickness of the film decreases. As measured in  STM, the molecules in the first layer adsorb with the porphyrin  rings parallel to the surface, while the phenyl rings are  essentially upright on both surfaces.
Elasmus westwoodi Giraud
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 35. Elasmus westwoodi Giraud
Material examined. See Yefremova & Strakhova (2012).
Hosts. Ectoparasitoid of Pseudoterna pruinata Hüfnagel (Lepidoptera: Geometridae) and hyperparasitoid of Apanteles sp. (Braconidae) (Yefremova & Strakhova 2010).
Distribution. Israel (Yefremova & Strakhova 2012); Palearctic (Yefremova & Strakhova 2010).
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on pages 10-11, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546
Estrogen Formation and Breast Cancer Risk
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The past 20 years of research have identified numerous risk and protective factors for breast cancer, many of which can be understood as being associated with differences in lifetime exposure to the female hormone, estrogen. In general, estrogen causes increased cell division in breast cells and this is thought to increase the chance of errors in the genetic material of some cells, resulting in cancer development.

 Recently, two genes have been identified (called BRCA1 and 2), each one greatly enhancing the chance for breast cancer when any one of them carrying a mutation is inherited by a woman. However, it is estimated that only about 5% of all breast cancer in the U.S. is attributable to mutations in these two genes. We and others have proposed that several other genes might also contribute to breast cancer risk. Many such genes might each contribute only modestly to the risk of getting breast cancer. However, in the population at large, they might play important roles in combination due to their high prevalence. One such class of genes code for enzymes that control the formation of estrogen; the more active the enzyme, the more estrogen will be synthesized, the higher the risk is for breast cancer development. In this study we will focus on a candidate gene, called CYP17. This gene codes for the enzyme that specifically controls the ultimate formation of all estrogen in the body. Variant forms of this gene might be inherited by a woman. We have identified certain variant forms that might increase the risk for developing breast cancer, and this project will attempt to understand how these changes can cause differences in the enzyme’s activity and how these differences in turn might be related to risk of developing breast cancer.

 We believe that the basic information forthcoming from this, and other studies like this, will lead to the better understanding of the known family associations of breast cancer. Such knowledge, combined with information of other genes, might ultimately lead to the rational formulation of risk assessment of breast cancer in the general population.
T Cell immunotherapy of human breast cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: We hope to be able to use the body’s immune response to get rid of breast cancer cells remaining after high dose chemotherapy and stem cell transplantation. Among the white blood cells collected for the transplant are T cells, white blood cells capable of killing tumor cells specifically without injuring normal tissues. There are also other white blood cells capable of presenting foreign proteins (antigens) from the breast cancer cell to the T cells, so the T cells can react more strongly to the proteins. We propose to take the T cells and the other white blood cells after the stem cells needed for the transplant have been separated from them. We will then try to immunize two subtypes of T cells, T helper cells and T killer cells, with different fragments of the breast cancer protein, because each subtype responds best to a different sized fragment. It will be necessary to find out which fragments immunize best, and whether only one or two are needed to immunize the T cells of all patients.

 Special methods of putting the protein fragments into the antigen-presenting white blood cells, and of growing the T cells outside the body will be developed, with new molecules that conduct the fragments to the part of the antigen-presenting cell where they will be presented best, and with new T cell-growth stimulating substances. Methods of doing these procedures in a clinically relevant way will be developed too, which will enable them to be used together with, or immediately after, the stem cell transplantation itself. We will immunize the patients later, to keep their level of immunity high. As an essential part of this study, we will adapt assays we already use in our laboratory to measure how many anti-breast cancer T cells are circulating in the patient at various times after the T cells are put back and after the patient is immunized. These experiments will not only help us in treating breast cancer patients with helper and killer T cells, they will also tell us what parts of the breast cancer protein patients most strongly react to, enabling the further scientific development of specific breast cancer vaccines.
Herpetocythere gnoma Hart & Hart 1967, sp. nov.
Creators: name: Williams, Bronwyn W.
name: Weaver, Patricia G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Ostracoda
Herpetocythere
Herpetocythere gnoma

description: Herpetocythere gnoma Hart & Hart, 1967
1967b Herpetocythere gnoma sp. nov. —Hart & Hart: 8, 17, 21–22, 23, 42, 43, Figs. 55–60 (A, D, H, K, R, T).
1974 Herpetocythere gnoma Hart and Hart, 1967.—Hart & Hart: 145, 149, 150, 216, 236, Pl. XL Figs. 1 –6, Pl. LX (C, D, H, K, R, T).
1975 Herpetocythere gnoma Hart & Hart, 1967.—Hart & Hart: 56 (C, D, H).
2014a Herpetocythere gnoma Hart & Hart, 1967.—Mestre, Monrós & Mesquita-Joanes: 950 (C).
description: Published as part of Williams, Bronwyn W. & Weaver, Patricia G., 2018, A historical review of the taxonomy and classification of Entocytheridae (Crustacea: Ostracoda: Podocopida), pp. 1-129 in Zootaxa 4448 (1) on page 101, DOI: 10.11646/zootaxa.4448.1.1, http://zenodo.org/record/1444492
Herpetocythere labidioides Hart & Hart 1967, sp. nov.
Creators: name: Williams, Bronwyn W.
name: Weaver, Patricia G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Ostracoda
Herpetocythere
Herpetocythere labidioides

description: Herpetocythere labidioides Hart & Hart, 1967
1967b Herpetocythere labidioides sp. nov. —Hart & Hart: 6, 8, 19, 21, 22, 23, 26, 42, 43, Fig. 54 (A, D, H, K, R, T).
1974 Herpetocythere labidioides Hart and Hart, 1967.—Hart & Hart: 145, 150–151, 216 [as Herpetocythere labidoides, erroneous spelling], 236, Pl. XL Fig. 7, Pl. LX (C, D, H, K, R, T).
1975 Herpetocythere labidioides Hart & Hart, 1967.—Hart & Hart: 56 (C, D, H).
2014a Herpetocythere labidioides Hart & Hart, 1967.—Mestre, Monrós & Mesquita-Joanes: 950 (C).
description: Published as part of Williams, Bronwyn W. & Weaver, Patricia G., 2018, A historical review of the taxonomy and classification of Entocytheridae (Crustacea: Ostracoda: Podocopida), pp. 1-129 in Zootaxa 4448 (1) on page 101, DOI: 10.11646/zootaxa.4448.1.1, http://zenodo.org/record/1444492
Responses of mouse macrophages to oxidative stress
Creators: name: Connor, Agnieszka
Publisher: name: No Publisher Supplied
Year: 2012

description: Tissue injury induced by infections or xenobiotics is associated with oxidative stress and inflammation, which are thought to contribute to pathogenic response.  We hypothesized that toll-like receptor 4 (TLR4) is important in macrophage responsiveness to oxidative stress.  To test this, we compared the response of TLR4 mutant C3H/HeJ mice and control C3H/HeOuJ mice to ozone and to bacterially-derived lipopolysaccharide (LPS).  Exposure of C3H/HeOuJ mice to ozone (0.8 ppm for 3 h) resulted in increases in bronchoalveolar lavage lipocalin 24p3, 4-hydroxynonenal, surfactant protein-D, macrophage and protein content.  Increased nuclear binding activity of NF-B and expression of TNF mRNA was also noted in lung macrophages.  Findings that these responses to ozone were reduced in C3H/HeJ mice demonstrate that functional TLR4 contributes to ozone-induced injury, inflammation, and oxidative stress.  We next determined if lung and liver macrophage responses to LPS are also mediated by TLR4.  Treatment of control C3H/HeOuJ mice with LPS (3 mg/ml) resulted in increased numbers of macrophages in liver and lung after 48 h.  In liver, but not lung macrophages, a rapid increase in mRNA expression of MnSOD and HO-1, as well as COX-2 and microsomal prostaglandin E synthase-1 was also observed.  Conversely, macrophage COX-2 protein expression increased in both macrophage populations. The effects of LPS were significantly reduced in C3H/HeJ mice indicating TLR4 is also involved in LPS-induced oxidative stress, inflammation and macrophages activation in the liver and lung.   To investigate mechanisms regulating macrophage responses, we evaluated the effects of hypoxia-induced oxidative stress on LPS-induced activation of macrophages using RAW 264.7 murine macrophages.  Hypoxia augmented the effects of LPS on iNOS, COX-2, IL-1, GLUT-1 and VEGF-A mRNA expression.  Hypoxia also upregulated LPS-induced protein expression of iNOS and COX-2, as well as MnSOD, lipocalin 24p3, and MMP-9.  Some of these responses were dependent on p44/42 mitogen activated protein kinase signaling.    Taken together, these studies demonstrate a key role of TLR4 in both sterile and infection driven inflammatory responses.  These findings may be important in the development of effective therapeutics for treating diseases associated with prominent macrophages inflammatory responses.
Eulophus slovacus Boucek
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 36. Eulophus slovacus Bouček
Material examined. 1 ♀, 1 ♂, Israel Giv’at Olga, Nahal Poleg, 12.iii.1996, N. Dorchin ex. Cecidomyiidae (Lasioptera umbelliferarum) from stem galls of Bilacunaria boissieri.
Hosts. Ectoparasitoid of Lymantriidae (Lepidoptera) (Bouček & Askew 1968); new host-record L. umbelliferarum Kieffer (Cecidomyiidae).
Distribution. Israel *; Palearctic (Bouček 1977; Kalina 1989).
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on page 11, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546
Understanding Tamoxifen - A Drug for Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tamoxifen is a widely used drug that is known to prevent breast cancer growth. When breast cancer first arises the cancer cells often continue to require estrogen to grow, just as their normal counterparts do. The requirement for estrogen provides an unparalleled opportunity to control the growth of the cancer. Tamoxifen acts by opposing the action of estrogens, and is therefore termed an antiestrogen. This property means that tamoxifen will arrest estrogen-dependent breast cancer growth while other treatments, such as surgery and chemotherapy, can be tried. Tamoxifen treatment for breast cancer has proven very successful. It is even presently proposed that tamoxifen should be given to healthy women to prevent formation of breast cancer. Unfortunately, this is not without risks. Instead of opposing estrogen action, tamoxifen can sometimes act just like estrogen. In women who take tamoxifen, this can result in stimulation of the growth of later stage breast tumors and increases in the risk of cancer of the uterus. Our goal is to understand how tamoxifen causes these estrogen-like effects and to use this knowledge to design better cancer blocking drugs. Estrogen acts by binding to a specific protein, called the estrogen receptor that, in turn, stimulates cell growth. Tamoxifen binds to the estrogen receptor protein, and dislodges estrogen from the estrogen binding pocket on the receptor. We recently showed that tamoxifen, when attached to the estrogen receptor protein, stimulates the activity of certain proteins (AP-1) that are normally involved in cell growth and may be important in cancer development.

 In this project we will study tamoxifen activity on AP-1 in cell culture models that are easy to manipulate. We will then use genetic and biochemical approaches to understand how tamoxifen stimulates AP-1 activity and how the estrogen-like effects of tamoxifen on cancer growth might arise. We hope to use this work to develop screening systems that will tell us whether new breast cancer drugs might have similar harmful effects, and to identify new strategies for preventive drug design. New antiestrogens with more desirable properties have the potential to reduce the human and economic costs of breast cancer in California.
Trochidae Rafinesque 1815
Creators: name: Leal, José H.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Trochida
Trochidae

description: Family Trochidae
Umbonium eloiseae Dance, Molenbeek, & Dekker, 1992; one paratype.
Unassigned family Lodderena bunnelli Redfern & Rolán, 2005 (Figure 4); twenty paratypes.
description: Published as part of Leal, José H., 2021, Type specimens in the molluscan collection of the Bailey-Matthews National Shell Museum, Florida, USA, pp. 1-40 in Zootaxa 4951 (1) on page 3, DOI: 10.11646/zootaxa.4951.1.1, http://zenodo.org/record/4655535
Genetic Changes in Normal Epithelium of the Cancerous Breast
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Less than 10% of breast cancer cases are genetically inherited. In other words, the majority of women diagnosed with breast cancer do not have an alteration in breast cancer predisposition genes. However, genetic alterations are a hallmark of malignancy, presumably detectable at all stages of tumorigenesis. Although, primarily unknown, the nature and the extent of such changes are major determinants of tumor progression and outcome for all patients. It seems plausible that since the genes mutated in familial breast cancer regulate important cellular pathways, they must play a role in other type of breast tumor as well. Surprisingly, unlike familial breast cancer, mutation in these genes have not bee reported in sporadic breast cancer, yet genetic deletion at these sites is relatively common.

 Taken together, these facts suggest that deletions of breast cancer disposition genes may be among the earliest alterations detectable in precursor lesions in the cancerous field surrounding the primary tumor. To ascertain this possibility, it is obligatory that the molecular analysis of tumors should encompass the entire spectrum of precursors involved in the genesis of sporadic breast cancer. However the identity of these precursors remains to be fully established. Our major goal in this study is to test the hypothesis that morphologically normal epithelium within the cancerous field represents the earliest precursor of breast tumors and displays specific genetic deletions prior to widespread genetic instability, characteristic of malignant cells.

 This application proposes to obtain insights regarding the underlying genetic factors in the transition from histologically normal breast epithelium to atypia, preinvasive, and invasive disease. Overall, this study will take steps towards defining the specific temporal sequence of events at the genetic level in breast tumorigenesis. Alterations detectable at the earliest stages could offer strategies for arresting further progression. Moreover, the application of objective methods for establishing coexistence of tumor cell progenitors in diseased tissue can serve to identify and aggressively treat patients who may be at a great risk for the development of a new ipsilateral and/or contralateral primary tumor.
Neritidae
Creators: name: Leal, José H.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Cycloneritimorpha
Neritidae

description: Family Neritidae
Clithon cryptum Eichhorst, 2016 (Figure 5); holotype and two paratypes.
Clithon teres Eichhorst, 2016 (Figure 6); holotype and three paratypes.
Nereina cresswelli Eichhorst, 2016 (Figure 7); holotype and one paratype.
Neripteron subviolaceum Eichhorst, 2016 (Figure 8); holotype and two paratypes.
Nerita grasi Eichhorst, 2016 (Figure 9); holotype and one paratype.
Neritina janetabbasae Eichhorst, 2016 (Figure 10); holotype and one paratype.
Neritodryas javanica Eichhorst, 2016 (Figure 11); holotype and one paratype.
Septaria tahitiana Eichhorst, 2016 (Figure 12); holotype and one paratype.
Smaragdia patburkae Eichhorst, 2016 (Figure 13); holotype and five paratypes.
Theodoxus octagonus Eichhorst, 2016 (Figure 14); holotype and three paratypes.
Vitta consobrina Eichhorst, 2016 (Figure 15); holotype.
description: Published as part of Leal, José H., 2021, Type specimens in the molluscan collection of the Bailey-Matthews National Shell Museum, Florida, USA, pp. 1-40 in Zootaxa 4951 (1) on page 4, DOI: 10.11646/zootaxa.4951.1.1, http://zenodo.org/record/4655535
Herpetocythere mackenziei Hart & Hart 1967, sp. nov.
Creators: name: Williams, Bronwyn W.
name: Weaver, Patricia G.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Ostracoda
Herpetocythere
Herpetocythere mackenziei

description: Herpetocythere mackenziei Hart & Hart, 1967
1967b Herpetocythere mackenziei sp. nov. —Hart & Hart: 6, 8, 19–20, 21, 26, 42 [as Herpetocythere mackensiei, erroneous spelling], 43, Figs. 48–49 (A, D, H, K, R, T).
1974 Herpetocythere mackenziei Hart and Hart, 1967.—Hart & Hart: 146, 151, 216, 236, Pl. XL Figs. 8–9, Pl. LX (C, D, H, K, R, T).
1975 Herpetocythere mackensiei Hart & Hart, 1967.—Hart & Hart: 56 (C, D, H).
2014a Herpetocythere mackenziei Hart & Hart, 1967.—Mestre, Monrós & Mesquita-Joanes: 950 (C).
description: Published as part of Williams, Bronwyn W. & Weaver, Patricia G., 2018, A historical review of the taxonomy and classification of Entocytheridae (Crustacea: Ostracoda: Podocopida), pp. 1-129 in Zootaxa 4448 (1) on page 101, DOI: 10.11646/zootaxa.4448.1.1, http://zenodo.org/record/1444492
Pickworthiidae Iredale 1917
Creators: name: Leal, José H.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Littorinimorpha
Pickworthiidae

description: Family Pickworthiidae
Mareleptopoma circumserrata Raines, 2002 (Figure 16); one paratype.
description: Published as part of Leal, José H., 2021, Type specimens in the molluscan collection of the Bailey-Matthews National Shell Museum, Florida, USA, pp. 1-40 in Zootaxa 4951 (1) on page 4, DOI: 10.11646/zootaxa.4951.1.1, http://zenodo.org/record/4655535
The use of experimental petrology to generate an impact model for formation of the unique CBb chondrules
Creators: name: Condie, Claire
Publisher: name: No Publisher Supplied
Year: 2012

description: In this research, an impact between the protoplanet Pallas, which hosts a large crater and has a surface composition very similar to the CR carbonaceous chondrites and an iron-nickel impactor, is suggested to be the formation mechanism for the CBb chondrules.  The CBb chondrules may have formed by melting, evaporation and condensation, possibly in the vapor cloud generated by the impact between Pallas and the iron-nickel impactor.      Through experimental petrology, the skeletal olivine (SO) texture of the CBb chondrules has been replicated using cooling-reheating cycles.  By combining my new cooling-reheating temperature data for the formation of the CBb chondrules with previous research  a unified impact model has been developed for the CBb chondrites and their genetically related partners, CBa, CH, and CR. .
The tipping point
Creators: name: Cholewiak, Steven A.
Publisher: name: No Publisher Supplied
Year: 2012

description: Vision research generally focuses on the currently visible surface properties of objects, such as color, texture, luminance, orientation, and shape.  In addition, however, observers can also visually predict the physical behavior of objects, which often requires inferring the action of hidden forces, such as gravity and support relations.  One of the main conclusions from the naive physics literature is that people often have inaccurate physical intuitions; however, more recent research has shown that with dynamic simulated displays, observers can correctly infer physical forces (e.g., timing hand movements to catch a falling ball correctly takes into account Newton’s laws of motion).  One ecologically important judgment about physical objects is whether they are physically stable or not.  This research project examines how people perceive physical stability and addresses (1) How do visual estimates of stability compare to physical predictions? Can observers track the influence of specific shape manipulations on object stability? (2) Can observers match stability across objects with different shapes? How is the overall stability of an object estimated? (3) Are visual estimates of object stability subject to adaptation effects? Is stability a perceptual variable?  The experimental findings indicate that: (1) Observers are able to judge the stability of objects quite well and are close to the physical predictions on average.  They can track how changing a shape will affect the physical stability; however, the perceptual influence is slightly smaller than physically predicted.  (2) Observers can match the stabilities of objects with different three-dimensional shapes -- suggesting that object stability is a unitary dimension -- and their judgments of overall stability are strongly biased towards the minimum critical angle. (3) The majority of observers exhibited a stability adaptation aftereffect, providing evidence in support of the claim that stability may be a perceptual variable.
Static and dynamic properties of CN/Cu(001) surfaces and oxidation, dissociation and bimolecular debarboxylation of isocyanate species adsorbed on Cu(001)
Creators: name: Ciftlikli, Erkan Ziya
Publisher: name: No Publisher Supplied
Year: 2012

description: This dissertation presents an outlines my investigations of static and dynamic properties of adsorbed cyanide (CN) and isocyanate (-NCO) species as well as some of their chemistries. Surface bound CN-containing species have not previously been studied extensively, partially due to the inapplicability of fundamental e-beam based surface analysis techniques for investigations. I had the opportunity in my studies to employ multiple surface probing techniques, i.e. HAS, XPS, NEXAFS, TPD and RAIRS, to compile and cross-examine information from CN, –NCO, and derived species, adsorbed on the Cu(001) surface. While angle resolved He atom scattering (HAS) was employed to identify and investigate the ordered superstructure of CN/Cu(001) surfaces, TOF-HAS was employed to investigate its dynamic properties. The CN/Cu(001) surface induced unprecedented simultaneous coherent He diffraction with a large “classical” multiphonon backscattered He intensity. A superstructure is implied that contains both rigidly bound CN species, which maintain the long range c(10x6) translational symmetry, together with bound highly-dynamic CN species that exhibit large thermally induced displacements. The NEXAFS measurements suggest multiple spatial binding configurations for the adsorbed CN moieties. In addition, TPD spectra of C2N2 desorption from CN/Cu(001) surface were analyzed, using my newly developed method, to determine the activation energies for desorption as a function of CN coverage. There are two reactions of NCO species examined in my studies. The first is the newly discovered mutual reaction between NCO species. This type of interaction had not been seen before, as it is essentially difficult to prepare pure NCO/metallic surfaces. Copper was chosen as a substrate as HNCO exposures of Cu(001) at RT, followed by spontaneous H2 desorption, do produce NCO only surfaces. A thermal treatment of the surface, at 573K, leads to a bimolecular decarboxylation of NCO, leaving a carbodimide species (NCN) on the surface. The sp-hybridized linear NCN moieties, which are bound nearly parallel to the substrate, show high thermal stability. The second reaction of NCO, which I have studied, is its oxidation. In particular, the effect of CN coadsorbates on the oxidation of NCO was studied. It was found that the presence of CN catalyzes a dissociation reaction of NCO species on Cu(001).
The study of CMOS based VCO with active inductor and its design methodology
Creators: name: Chueng, Sy-Min
Publisher: name: No Publisher Supplied
Year: 2012

description: Active Inductors are useful in reducing the large chip area typically consumed by spiral inductors, as well as providing larger inductance values and higher quality factors that otherwise cannot be achieved by spiral inductors. Integrated inductors find application in many radio frequency (RF) front end integrated circuits, including impedance matching, filtering, biasing and in oscillator circuits. Nonetheless, because of the interdependent relationship of the self-resonant frequency and  quality factor it is often difficult to meet desired circuit requirements. Additionally, active devices pose problems of higher power consumption , noise figure and potential instability. This thesis begins with the study of active inductors, the Wu active inductor in particular, and considers tuning methods based on the Wu active inductor topology. Starting with the small-signal model, the emulated inductance and quality factor expressions are derived. Next, the operation of active inductors under large-signal is closely examined. Comparisons between a passive and an active VCO are made.  The active inductor based voltage-controlled oscillator (Active VCO) is studied extensively, and the methods of improving the performance under large signal-behavior are discussed. Then a design procedure based on gm/ID methodology is proposed. A Matlab script that can be applied to gyrator-C based active inductors is developed to determine the sizing of the transistors for a desired inductance and resonant frequency.  Cadence Virtuoso is used for simulations, and  extraction based on an IBM 8RF technology file. Finally, a low power active VCO is designed, simulated and laid out.
Eulophus thespius Walker
Creators: name: Yefremova, Zoya A.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy

description: 37. Eulophus thespius Walker
Material examined. 2 ♀, Israel, Hermon, 2200m, sweeping, 22.v.1973 (D. Furth); 1 ♀, Hermon, 2200m, sweeping, 3.v.1979 (D. Furth).
Hosts. Ectoparasitoid of Geometridae (Lepidoptera) (Bouček & Askew 1968). Distribution. Israel *; Palearctic (Bouček 1977; Kalina 1989; Boyadzhiev 1997, 2004).
description: Published as part of Yefremova, Zoya A., 2015, An annotated checklist of the Eulophidae (excl. Tetrastichinae) (Hymenoptera: Chalcidoidea) of Israel, pp. 1-36 in Zootaxa 3957 (1) on page 11, DOI: 10.11646/zootaxa.3957.1.1, http://zenodo.org/record/288546