cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Classification of parathyroid cancer.
Creators: name: Diaz-Cano, Salvador J.
name: K M Schulte
name: N Talat
name: M Barczynski
name: A Miyauchi
name: C P Lombardi
name: C S Grant
name: A J Gill
name: W T Knoefel
name: E Karakas
Publisher: name: figshare
Year: 2012
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: Science Policy
subject: Medicine
subject: Cell Biology
subject: Cancer

description: Parathyroid cancer is rare and often has a poor outcome. There is no classification system that permits prediction of outcome in patients with parathyroid cancer. This study was designed to validate two prognostic classification systems developed by Talat and Schulte in 2010 ("Clinical Presentation, Staging and Long-term Evolution of Parathyroid Cancer," Ann Surg Oncol 2010;17:2156-74) derived from a retrospective literature review of 330 patients.
 This study contains 82 formerly unreported patients with parathyroid cancer. Death due to disease was the primary end point, and recurrence and disease-free survival were the secondary end points. Data acquisition used a questionnaire of predefined criteria. Low risk was defined by capsular and soft tissue invasion alone; high risk was defined by vascular or organ invasion, and/or lymph node or distant metastasis. A differentiated classification system further classified high-risk cancer into vascular invasion alone (class II), lymph node metastasis or organ invasion (class III), and distant metastasis (class IV). Statistical analyses included risk analysis, Kaplan-Meier analysis, and receiver-operating characteristic (ROC) analysis.
 Follow-up ranged 2-347 months (mean 76 months). Mortality was exclusive to the high- risk group, which also predicted a significant risk of recurrence (risk ratio 9.6; 95% confidence interval 2.4-38.4; P < 0.0001), with significantly lower 5-year disease-free survival (χ(2) = 8.7; P < 0.005 for n = 45). The differentiated classification also provided a good prognostic model with an area under the ROC curve of 0.83 in ROC analysis, with significant impairment of survival between classes (98.6%, 79.2%, 71.4%, 40.0%, P < 0.05 between each class).
 This study confirms the validity of both classification systems for disease outcome in patients with parathyroid cancer.
Magnetic coupling through flux branching of adjacent type-I and -II superconductors in a neutron star
Creators: name: Thong, K. H.
name: Melatos, A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Superconductivity (cond-mat.supr-con)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The inner and outer cores of neutron stars are believed to contain type-I and -II proton superconductors, respectively. The type-I superconductor exists in an intermediate state, comprising macroscopic flux-free and flux-containing regions, while the type-II superconductor is flux-free, except for microscopic, quantized flux tubes. Here, we show that the inner and outer cores are coupled magnetically, when the macroscopic flux tubes subdivide dendritically into quantized flux tubes, a phenomenon called flux branching. An important implication is that up to $\sim 10^{12} (r_1/10^6 \, {\rm cm}) \, {\rm erg}$ of energy are required to separate a quantized flux tube from its progenitor macroscopic flux tube, where $r_1$ is the length of the macroscopic flux tube. Approximating the normal-superconducting boundary as sharp, we calculate the magnetic coupling energy between a quantized and macroscopic flux tube due to flux branching as a function of, $f_1$, the radius of the type-I inner core divided by the radius of the type-II outer core. Strong coupling delays magnetic field decay in the type-II superconductor. For an idealised inner core containing only a type-I proton superconductor and poloidal flux, and in the absence of ambipolar diffusion and diamagnetic screening, the low magnetic moments ($\lesssim 10^{27} \, {\rm G \, cm^3}$) of recycled pulsars imply $f_1 \lesssim 10^{-1.5}$.
Chances of late surgery in relation to length of wait lists
Creators: name: Sobolev, Boris
name: Levy, Adrian R.
name: Kuramoto, Lisa
name: Hayden, Robert
Publisher: name: BioMed Central
Year: 2016

description: Background: The proportion of patients who undergo surgery within a clinically safe time is an important performance indicator in health systems that use wait lists to manage access to care. However, little is known about chances of on-time surgery according to variations in existing demand. We sought to determine what proportion of patients have had late coronary bypass surgery after registration on wait lists of different size in a network of hospitals with uniform standards for timing of surgery. Methods: Using records from a population-based registry, we studied wait-list times prospectively collected in a cohort of patients registered on wait lists for coronary artery bypass grafting procedures. We compared the number of weeks from registration to surgery against target access times established for three urgency groups. The chances of undergoing surgery within target time have been evaluated in relation to wait-list size at registration and the number of surgeries performed without registration on a wait list. Results: In 1991–2001, two in three patients were at risk of late surgery when registered on wait lists for isolated coronary bypass procedures in British Columbia, Canada. Although urgent patients had never seen a wait list with clearance time exceeding one week, the odds of on-time surgery were reduced by 25%, odds ratio [OR] = 0.75 (95% confidence interval [CI] 0.65–0.87) for every additional operation performed without registration on a list. When the wait list at registration required a clearance time of over one month, semi-urgent patients had 51% lower odds of on-time surgery as compared to lists with clearance time less than one week, OR = 0.49 (95%CI 0.41–0.60), after adjustment for age, sex, comorbidity, calendar period, hospital and week on the list. In the non-urgent group, the odds were 69% lower, OR = 0.31 (95%CI 0.20–0.47). Every time an operation in the same hospital was performed without registration on a wait list, the odds of on-time surgery for listed patients were reduced by 7%, OR = 0.93 (95%CI 0.91–0.95) in the semi-urgent group, and by 10%, OR = 0.90 (95%CI 0.87–0.94), in the non-urgent group. Conclusion: Chances of late surgery increase with the wait-list size for semi-urgent and non-urgent patients needing coronary bypass surgery. The weekly number of patients who move immediately from angiography to the operation without registration on a wait list reduced chances of surgery within target time in all urgency groups of listed patients. When advising patients who will be placed on the wait list about the expected time to treatment, hospital managers should take into account the current list size as well as the weekly number of patients who require CABG immediately after undergoing coronary angiography.
Ageleradix Xu & Li 2007
Creators: name: Mu, Yan-Nan
name: Wang, Lu-Yu
name: Ren, Tian-Yu
name: Tian, Yuan
name: Zhang, Zhi-Sheng
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Agelenidae
Ageleradix

description: Ageleradix Xu & Li, 2007
Type species.
Ageleradix sichuanensis Xu & Li, 2007 (by original designation).
Diagnosis.
This genus is similar to Allagelena Zhang, Zhu & Song, 2006 in having centrally originated, extending distally and proximally and sclerotized conductor (C), but can be separated from it by: palpal patella lacking apophysis (vs. with apophysis), retrolateral tibial apophysis (RTA) not well developed (vs. well developed), embolus (E) slender (vs. thick), tegular apophysis (TA) well developed (vs. not well developed); scape (Sc) extending to middle part of epigynal plate (vs. absent or not extending to middle part), and atrium shallow (vs. deep).
Composition.
A. cymbiforma (Wang, 1991) (♀), A. otiforma (Wang, 1991) (♀ ♂), A. schwendingeri Zhang, Li & Xu, 2008 (♀ ♂), A. sichuanensis Xu & Li, 2007 (♀ ♂), A. sternseptum Zhang, Li & Xu, 2008 (♀) and A. zhishengi Zhang, Li & Xu, 2008 (♀ ♂), A. dulong Mu, Wang & Zhang sp. nov. (♀ ♂), A. jinfo shan Mu, Wang & Zhang sp. nov. (♀) and A. nangunhe Mu, Wang & Zhang sp. nov. (♀ ♂).
Distribution.
Known only from China (Yunnan, Sichuan, Xizang, Guangxi, Guizhou).
description: Published as part of Mu, Yan-Nan, Wang, Lu-Yu, Ren, Tian-Yu, Tian, Yuan & Zhang, Zhi-Sheng, 2025, Review of the genus Ageleradix Xu & Li, 2007 (Araneae, Agelenidae), with descriptions of three new species, pp. 197-208 in ZooKeys 1236 on pages 197-208, DOI: 10.3897/zookeys.1236.143650
Wie Religion für Krisen taugt. Zum Beitrag religiöser Bildung für Krisenzeiten, hg. v. Mirjam Schambeck / Winfried Verburg
Creators: name: Kropač, Ulrich
Publisher: name: Theologische Revue
Year: 2024

description: Theologische Revue, Bd. 120 (2024): August
title: Ð­Ð½ÑÑÐ¾Ð¿Ð¸Ñ, Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ñ Ð¸ ÑÐ¾ÑÐ½Ð¾ÑÑÑ Ð¾ÑÐµÐ½Ð¸Ð²Ð°Ð½Ð¸Ñ
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ¾ÑÐµÐ²Ð¸Ñ, ÐÐ»ÑÐ±ÐµÑÑ
name: Ð¡Ð¾Ð»ÐµÐ²Ð°, ÐÐ°Ð´ÐµÐ¶Ð´Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: Ð­Ð½ÑÑÐ¾Ð¿Ð¸Ñ
ÐÐ½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ñ
Ð½ÐµÑÐ°Ð²ÐµÐ½ÑÑÐ²Ð¾ ÐÑÐ»ÑÐ±Ð°ÐºÐ°-ÐÐµÐ¹Ð±Ð»ÐµÑÐ°
Ð½ÐµÑÐ°Ð²ÐµÐ½ÑÑÐ²Ð¾ Ð¤Ð°Ð½Ð¾
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° ÑÐ¶Ð°ÑÐ°Ñ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ñ Ð¿Ð¾ ÑÐ°ÐºÐ¸Ð¼ ÑÐµÐ¼Ð°Ð¼, ÐºÐ°Ðº: ÑÐ°ÑÑÑÐ¾ÑÐ½Ð¸Ðµ ÐÑÐ»ÑÐ±Ð°ÐºÐ°-ÐÐµÐ¹Ð±Ð»ÐµÑÐ°, ÑÐ½ÑÑÐ¾Ð¿Ð¸Ñ ÑÐ°Ð·Ð±Ð¸ÐµÐ½Ð¸Ñ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸ Ð¸ Ð½ÐµÑÐ°Ð²ÐµÐ½ÑÑÐ²Ð¾ Ð¤Ð°Ð½Ð¾.
Religionsunterricht weiterdenken. Innovative Ansätze für eine zukunftsfähige Religionsdidaktik, hg. v. Bernhard Grümme / Manfred L. Pirner
Creators: name: Uppenkamp, Vera
Publisher: name: Theologische Revue
Year: 2024

description: Theologische Revue, Bd. 120 (2024): August
AGN feeding along a one-armed spiral in NGC 4593: A study using ALMA CO(2-1) observations
Creators: name: Kianfar, K.
name: Andreani, P.
name: Fernández-Ontiveros, J. A.
name: Combes, F.
name: Spinoglio, L.
name: Hatziminaoglou, E.
name: Ricci, C.
name: Bewketu-Belete, A.
name: Imanishi, M.
name: Pereira-Santaella, M.
name: Slater, R.
name: Malheiro, M.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate active galactic nuclei (AGN) feeding through the molecular gas (CO(2-1) emission) properties of the local Seyfert 1 galaxy NGC 4593, using Atacama Large Millimeter Array (ALMA) observations and other multi-wavelength data. Our study aims to understand the interplay between the AGN and the interstellar medium (ISM) in this galaxy, examining the role of the AGN in steering gas dynamics within its host galaxy, evaluating the energy injected into the ISM, and determining whether gas is inflowing or outflowing from the galaxy. After reducing the ALMA CO(2-1) images, we employed two models, 3D-Barolo and DISCFIT, to construct a disc model and fit its emission to the ALMA data. Additionally, we used photometric data to build a spectral energy distribution (SED) and applied the CIGALE code to derive key physical properties of the AGN and its host. Our analysis reveals a complex interplay within NGC 4593, including a clear rotational pattern, the influence of a non-axisymmetric bar potential, and a central molecular zone (CMZ)-like ring. We observe an outflow of CO(2-1) gas along the minor axis, at a distance of approximately 220 pc from the nucleus. The total molecular gas mass is estimated to be between $1 - 5 \times 10^8 \, M_{\odot}$, with non-circular motions contributing about 10\%. Our SED analysis indicates an AGN fraction of 0.88 and a star formation rate (SFR) of 0.42 $M_{\odot} \, \text{yr}^{-1}$. These findings highlight the complex dynamics in the centre of NGC 4593, which are significantly influenced by the presence of the AGN. The overall physical properties of this system suggest that the AGN has a substantial impact on the evolution of NGC 4593.
description: 15 pages, 10 figures
IN-FDM-BB Werkstattbericht: W 2.2.2 Konzept für einen rechtlichen und ethischen First-Level-Support zum Forschungsdatenmanagement an den staatlich geförderten Hochschulen in Brandenburg
Creators: name: Sousa, Mariel
name: Binder, Matthieu
name: Horn, Nikolai
name: Berg, Katja
Publisher: name: Zenodo
Year: 2025
Subjects: Forschungsdatenmanagement
IN-FDM-BB
FDM-BB
iRights.Lab
FDM
Ethik
Recht
Kontaktpunkt
First-Level-Support

description: Der Umgang mit Forschungsdaten gehört zu den zentralen Aufgaben für Wissenschaftler*innen. Nicht zuletzt aufgrund der voranschreitenden Digitalisierung ergeben sich auch hier neue Fragestellungen, und die damit verbundenen Bedarfe für eine entsprechende Beratung und für digitale Services im Bereich des Forschungsdatenmanagements (FDM) wachsen stetig an.

In der Landesinitiative Forschungsdatenmanagement Brandenburg (FDM-BB) haben sich 2019 die acht staatlich geförderten Hochschulen des Landes Brandenburg zusammengeschlossen, um das Forschungsdatenmanagement in Brandenburg gemeinsam weiterzuentwickeln und Synergien zu nutzen. Seit 2022 arbeiten sie in dem vom Bundesministerium für Bildung und Forschung und vom Ministerium für Wissenschaft, Forschung und Kultur des Landes Brandenburg für drei Jahre geförderten Verbundprojekt „IN-FDM-BB: Institutionalisiertes und nachhaltiges Forschungsdatenmanagement in Brandenburg“ zusammen.

Ziele des Verbundprojekts IN-FDM-BB sind einerseits der lokale Kompetenzaufbau und die Institutionalisierung von Forschungsdatenmanagement an den brandenburgischen Hochschulen sowie andererseits der Aufbau von landesweiten Diensten und Dienstleistungen. Dazu gehört auch die Etablierung einer digitalen Infrastruktur, über die rechtliche und ethische Expertise zum Forschungsdatenmanagement gebündelt, aufbereitet und den Hochschulen als hochschulübergreifendes Angebot zur Verfügung gestellt wird. Dieses Arbeitspaket liegt bei der Europa-Universität Viadrina Frankfurt (Oder) (Viadrina), die hierbei von dem Think TankiRights.Lab (iRL) als Servicedienstleister unterstützt wird. 

Im Folgenden wird das Konzept zur Implementierung eines First-Level-Supports zur Beratung von rechtlichen und ethischen Fragen im Forschungsdatenmanagement in Form eines digitalen Kontaktpunkts dargestellt. Das Beratungsangebot richtet sich zum einen an Wissenschaftler*innen der brandenburgischen Hochschulen, die sich über die Website des Kontaktpunkts zu rechtlichen und ethischen Fragen im FDM informieren können, Material nutzen und Kontakt zu FDM-Personal ihrer Hochschule für eine individuelle Beratung aufnehmen können. Zum anderen richtet sich der Kontaktpunkt an die im Bereich FDM beratenden Mitarbeiter*innen der Hochschulen, die als Grundlage für ihre Beratung in einem internen Bereich der Website eine dynamische Materialsammlung finden.
Epigenetic predisposition to expression of TIMP1 from the human inactive X chromosome
Creators: name: Anderson, Catherine L.
name: Brown, Carolyn Janet
Publisher: name: BioMed Central
Year: 2015

description: Background: X inactivation in mammals results in the transcriptional silencing of an X chromosome in females, and this inactive X acquires many of the epigenetic features of silent chromatin. However, not all genes on the inactive X are silenced, and we have examined the TIMP1 gene, which has variable inactivation amongst females. This has allowed us to examine the features permitting expression from the otherwise silent X by comparing inactive X chromosomes with and without TIMP1 expression. Results Expression was generally correlated with euchromatic chromatin features, including DNA hypomethylation, nuclease sensitivity, acetylation of histone H3 and H4 and hypomethylation of H3 at lysines 9 and 27. Demethylation of the TIMP1 gene by 5-azacytidine was able to induce expression from the inactive X chromosome in somatic cell hybrids, and this expression was also accompanied by features of active chromatin. Acetylated histone H3 continued to be observed even when expression was lost in cells that naturally expressed TIMP1; while acetylation was lost upon TIMP1 silencing in cells where expression from the inactive X had been induced by demethylation. Thus ongoing acetylation of inactive X chromosomes does not seem to be simply a 'memory' of expression. Conclusion We propose that acetylation of H3 is an epigenetic mark that predisposes to TIMP1 expression from the inactive X chromosome in some females.
Design of Fiber-Longitudinal Optical Power Monitor
Creators: name: Sasai, Takeo
name: Set, Sze Yun
name: Yamashita, Shinji
Publisher: name: arXiv
Year: 2024
Subjects: subject: Signal Processing (eess.SP)
subject: Optics (physics.optics)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Physical sciences

description: This paper presents analytical results on the accuracy of fiber-longitudinal optical power monitoring (LPM) at arbitrary positions. To quantify the accuracy, the position-wise variance and power-profile SNR of LPM are defined and analyzed, yielding formulas for these metrics. Using these metrics, we show that various designs and performance predictions of LPM for a given link and estimation conditions are possible in a unified manner. Specifically, the required SNR to detect a given loss event is first presented. Based on this relation, the design parameters of LPM, such as the sample size and optical power required to detect the loss, are explicitly determined. The performance such as the detectable limit of loss events at individual positions and maximum dynamic range are also specified. These results can be used as a basis for establishing a design principle of LPM.
description: 11 pages, 13 figures, accepted version for Journal of Lightwave Technology
Jansson, Andreas C.: Der eine Sendungsdienst der Kirche: Ein Beitrag zur Verhältnisbestimmung von Evangelisation und Diakonie unter besonderer Berücksichtigung der Missionstheologie David J. Boschs
Creators: name: Bartholomä, Philipp
Publisher: name: Theologische Revue
Year: 2024

description: Theologische Revue, Bd. 120 (2024): August
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): Is cutaneous phenotype a prognostic marker for outcome? A review of clinicopathological features of 27 cases.
Creators: name: Diaz-Cano, Salvador J.
name: D Creamer
name: E Higgins
name: R Morris-Jones
name: S Bashir
name: S Walsh
name: W Bernat
Publisher: name: figshare
Year: 2012
Subjects: subject: Toxicology
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine

description: Introduction: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) describes a heterogenous group of severe adverse reactions to medications. The cutaneous phenotype has a number of guises, accompanied by a variety of systemic features including fever, haematological abnormalities and visceral involvement, most commonly the liver. Clinical markers of prognosis have not been identified. Methods: We reviewed the clinical features, dermatopathology and outcomes of 27 consecutive cases of DRESS presenting to a single unit. Results: 4 distinct patterns of cutaneous involvement were identified: an urticated papular exanthem (13/27 patients), a morbilliform erythema (3/27), an exfoliative erythroderma (3/27) and an erythema multiforme-like (EM-like) reaction consisting of atypical targets (8/27). All patients mounted a fever, most developed lymphadenopathy (24/27) and a peripheral eosinophilia (25/27) and the most common organ involved was the liver (26/27). Review of dermatopathic features of patients with DRESS demonstrated a superficial spongiotic dermatitis in the majority of cases (16/27). A smaller number of cases showed basal cell vacuolar degeneration and necrotic keratinocytes (9/27). These patients with these biopsy findings more commonly had an erythema multiforme like cutaneous phenotype, and more severe hepatic involvement. 3 patients died, 2 following failed liver transplants. Conclusions: Our series is the first in which a detailed dermatological assessment has been made of consecutive patients presenting with DRESS, and the largest UK series to date. Our results suggest a possible prognostic role of the cutaneous and dermatopathic findings in DRESS in predicting the severity of visceral involvement in this syndrome.
FinQAPT: Empowering Financial Decisions with End-to-End LLM-driven Question Answering Pipeline
Creators: name: Singh, Kuldeep
name: Kaur, Simerjot
name: Smiley, Charese
Publisher: name: arXiv
Year: 2024
Subjects: subject: Information Retrieval (cs.IR)
subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: I.2.7; H.3.3; I.2.6; I.5.3

description: Financial decision-making hinges on the analysis of relevant information embedded in the enormous volume of documents in the financial domain. To address this challenge, we developed FinQAPT, an end-to-end pipeline that streamlines the identification of relevant financial reports based on a query, extracts pertinent context, and leverages Large Language Models (LLMs) to perform downstream tasks. To evaluate the pipeline, we experimented with various techniques to optimize the performance of each module using the FinQA dataset. We introduced a novel clustering-based negative sampling technique to enhance context extraction and a novel prompting method called Dynamic N-shot Prompting to boost the numerical question-answering capabilities of LLMs. At the module level, we achieved state-of-the-art accuracy on FinQA, attaining an accuracy of 80.6%. However, at the pipeline level, we observed decreased performance due to challenges in extracting relevant context from financial reports. We conducted a detailed error analysis of each module and the end-to-end pipeline, pinpointing specific challenges that must be addressed to develop a robust solution for handling complex financial tasks.
description: Accepted in ICAIF 2024, 8 pages, 5 figures, 4 tables
„Nicht Konkurrenten, sondern Brüder…“. Auf dem Weg zu einem neuen Miteinander von orthodoxer und katholischer Kirche, hg. v. Dietmar Schon
Creators: name: Röhrig, Hermann-Josef
Publisher: name: Theologische Revue
Year: 2024

description: Theologische Revue, Bd. 120 (2024): August
Hildebrandt-Wackwitz, Lina: Schuld und Narration. Zur anthropologischen Bedingtheit und narrativen Aufarbeitung von Schuld in Auseinandersetzung mit Søren Kierkegaard, Hannah Arendt und Paul Ricœur
Creators: name: Rosenberger, Michael
Publisher: name: Theologische Revue
Year: 2024

description: Theologische Revue, Bd. 120 (2024): August
The synthesis of Androgen and Estrogen from cholesterol presented as a SBGN diagram
Creators: name: Sridhar, Aruna
name: Mazein, Alexander
name: Watterson, Steven
name: Roy, Douglas
name: Ghazal, Peter
Publisher: name: figshare
Year: 2012
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Genetics
subject: Developmental Biology
subject: Cell Biology

description: A pathway diagram describing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
Employee Needs according to ERG theory and Interpersonal Relationship inOrganization Affecting Organizational Conflict in Electronic IndustryThat affects conflicts in organizations in the electronics industry
Creators: name: Nartrapee Chaimongkol
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University
Year: 2019
Subjects: Needs according to ERG theory
Interpersonal Relationship
Organizational Conflict

description: Journal of Management Science Nakhon Pathom Rajabhat University, 6, 2, 263-280
Service Quality Affecting Efficiency in Tax Collectionof Kanchanaburi Area Excise Office
Creators: name: Waranya Thinsamran
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University
Year: 2019
Subjects: Quality service
Efficiency on tax collection
Tax collection

description: Journal of Management Science Nakhon Pathom Rajabhat University, 6, 2, 281-296
PET mapping of receptor occupancy using joint direct parametric reconstruction
Creators: name: Marin, Thibault
name: Belov, Vasily
name: Chemli, Yanis
name: Ouyang, Jinsong
name: Najmaoui, Yassir
name: Fakhri, Georges El
name: Duvvuri, Sridhar
name: Iredale, Philip
name: Guehl, Nicolas J.
name: Normandin, Marc D.
name: Petibon, Yoann
Publisher: name: arXiv
Year: 2024
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: Receptor occupancy (RO) studies using PET neuroimaging play a critical role in the development of drugs targeting the central nervous system (CNS). The conventional approach to estimate drug receptor occupancy consists in estimation of binding potential changes between two PET scans (baseline and post-drug injection). This estimation is typically performed separately for each scan by first reconstructing dynamic PET scan data before fitting a kinetic model to time activity curves. This approach fails to properly model the noise in PET measurements, resulting in poor RO estimates, especially in low receptor density regions. Objective: In this work, we evaluate a novel joint direct parametric reconstruction framework to directly estimate distributions of RO and other kinetic parameters in the brain from a pair of baseline and post-drug injection dynamic PET scans. Methods: The proposed method combines the use of regularization on RO maps with alternating optimization to enable estimation of occupancy even in low binding regions. Results: Simulation results demonstrate the quantitative improvement of this method over conventional approaches in terms of accuracy and precision of occupancy. The proposed method is also evaluated in preclinical in-vivo experiments using 11C-MK-6884 and a muscarinic acetylcholine receptor 4 positive allosteric modulator drug, showing improved estimation of receptor occupancy as compared to traditional estimators. Conclusion: The proposed joint direct estimation framework improves RO estimation compared to conventional methods, especially in intermediate to low-binding regions. Significance: This work could potentially facilitate the evaluation of new drug candidates targeting the CNS.
Electrochemical Investigation of Thin Nickel, Copper and Silver Films Interfaced with Yttria-Stabilized Zirconia
Creators: name: Fee, Michele
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Thin Films
Electrochemical Promotion of Catalysis
Cyclic Voltammetry
Silver
Copper
Nickel
Solid State Electrochemistry

description: The electrochemical investigation of nickel, copper and silver thin films interfaced with yttria stabilized zirconia (YSZ) solid electrolyte was accomplished to determine their response to polarization in dilute oxygen environments at 350 °C and assess their viability for electrochemical promotion of catalysis (EPOC). Polycrystalline YSZ (8 mol % Y2O3-ZrO2) pellets were synthesized in the lab and films deposited onto them using evaporative physical vapor deposition (PVD). The critical thickness of copper, silver and nickel thin films were foundusing in-situ resistance measurements. Following this, 50 and 100 nm copper and nickel films were studied using solid electrolyte cyclic voltammetry (SECV) to determine their response to polarization. Given that silver thin films at such thicknesses are thermally unstable, a film of 800 nm was used in this study. The materials were found to respond to polarization in different ways, forming oxides according to Wagner and Mott-Cabrera oxidation models.
Ageleradix jinfoshan Mu, Wang & Zhang 2025, sp. nov.
Creators: name: Mu, Yan-Nan
name: Wang, Lu-Yu
name: Ren, Tian-Yu
name: Tian, Yuan
name: Zhang, Zhi-Sheng
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Agelenidae
Ageleradix
Ageleradix jinfoshan

description: Ageleradix jinfoshan Mu, Wang & Zhang sp. nov.
Chinese name: 金佛山漏斗蛛 Fig. 3
Type material.
Holotype • ♀, China, Chongqing Mun., Nanchuan Dist., Jinfo Mt Reserve (Gufo Cave); 29°2'6.93"N, 107°11'32.14"E, elev. 2043 m, 4.09.2024, leg. Z. S. Zhang.
Etymology.
The specific name is derived from the type locality (jinfoshan = Jinfo mountain); noun in apposition.
Diagnosis.
The new species resembles A. zhishengi in having similar-shaped anterior part of atrium (cf. Fig. 3 B, C, and fig. 29 A, B in Zhu et al. 2017), but can be differentiated from it by: 1) septum (Se) reaching posterior edge of epigyne (Fig. 3 B) (vs. epigyne with scape, fig. 29 A in Zhu et al. 2017), and 2) copulatory duct (CD) nearly straight (Fig. 3 C) (vs. strongly curved, fig. 29 B in Zhu et al. 2017).
Description.
Female. Total length 7.94. Carapace: 3.68 long, 2.91 wide. Abdomen: 4.70 long, 2.95 wide. Eye sizes and interdistances: AME 0.22, ALE 0.24, PME 0.20, PLE 0.21, AME – AME 0.07, AME – ALE 0.06, PME – PME 0.19, PME – PLE 0.12, ALE – PLE 0.07. MOA: anterior width 0.44, posterior width 0.55, 0.48 long. Clypeus 0.10 long. Chelicerae with 3 promarginal and 3 retromarginal teeth. Leg measurements: I 11.84 (3.18, 4.07, 2.73, 1.86), II 10.26 (3.00, 3.29, 2.33, 1.64), III 10.19 (2.79, 3.29, 2.57, 1.54), IV 13.96 (3.83, 4.32, 3.81, 2.00). Carapace white-yellow, with U-shaped dark brown pattern. Cervical groove and radial grooves distinct. Fovea short, slightly depressed. Abdomen ovoid, gray; cardiac mark nearly as long as abdomen, red-brown. Anterior spinnerets shorter than basal segment of posterior-lateral spinnerets.
Epigyne as in Fig. 3 B, C. Atrium balloon-shaped, membranous, with distinct septum (Se) reaching posterior margin, more than 3 times longer than wide, with parallel margins. Copulatory opening (CO) located posteriorly. Copulatory ducts (CD) curved. Spermathecal head (SH) clavate. Spermathecae (S) fist-shaped, posteriorly located spaced by about 2 times diameter of spermathecae. Fertilization ducts (FD) extending antero-laterally.
Male. Unknown.
Distribution.
Known only from the type locality.
description: Published as part of Mu, Yan-Nan, Wang, Lu-Yu, Ren, Tian-Yu, Tian, Yuan & Zhang, Zhi-Sheng, 2025, Review of the genus Ageleradix Xu & Li, 2007 (Araneae, Agelenidae), with descriptions of three new species, pp. 197-208 in ZooKeys 1236 on pages 197-208, DOI: 10.3897/zookeys.1236.143650
Doelmatig en effectief
Creators: name: Driessen, Geert
Publisher: name: Didactief
Year: 2021
Subjects: NPO
COVID19
onderwijsachterstanden

description: De grootste uitdaging van het Nationaal Programma Onderwijs (NPO) is (1) dat het extra geld terechtkomt bij de kinderen die het het hardste nodig hebben, en (2) dat het vervolgens doelmatig en effectief wordt besteed.
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): Is cutaneous phenotype a prognostic marker for outcome? A review of clinicopathological features of 27 cases.
Creators: name: Diaz-Cano, Salvador J.
name: D Creamer
name: E Higgins
name: R Morris-Jones
name: S Bashir
name: S Walsh
name: W Bernat
Publisher: name: figshare
Year: 2013
Subjects: subject: Toxicology
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine

description: Introduction: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) describes a heterogenous group of severe adverse reactions to medications. The cutaneous phenotype has a number of guises, accompanied by a variety of systemic features including fever, haematological abnormalities and visceral involvement, most commonly the liver. Clinical markers of prognosis have not been identified. Methods: We reviewed the clinical features, dermatopathology and outcomes of 27 consecutive cases of DRESS presenting to a single unit. Results: 4 distinct patterns of cutaneous involvement were identified: an urticated papular exanthem (13/27 patients), a morbilliform erythema (3/27), an exfoliative erythroderma (3/27) and an erythema multiforme-like (EM-like) reaction consisting of atypical targets (8/27). All patients mounted a fever, most developed lymphadenopathy (24/27) and a peripheral eosinophilia (25/27) and the most common organ involved was the liver (26/27). Review of dermatopathic features of patients with DRESS demonstrated a superficial spongiotic dermatitis in the majority of cases (16/27). A smaller number of cases showed basal cell vacuolar degeneration and necrotic keratinocytes (9/27). These patients with these biopsy findings more commonly had an erythema multiforme like cutaneous phenotype, and more severe hepatic involvement. 3 patients died, 2 following failed liver transplants. Conclusions: Our series is the first in which a detailed dermatological assessment has been made of consecutive patients presenting with DRESS, and the largest UK series to date. Our results suggest a possible prognostic role of the cutaneous and dermatopathic findings in DRESS in predicting the severity of visceral involvement in this syndrome.
Transformational leadership of the administrators influenceon the success of the use of information technology.In Thawi Watthana District Office Bangkok.
Creators: name: Phothikul, Anan
Publisher: name: Faculty of Management Science Nakhon Pathom Rajabhat University
Year: 2019
Subjects: Influence of transformational leadership
success of using information technology

description: Journal of Management Science Nakhon Pathom Rajabhat University, 6, 2, 297-309
title: 卡大汗河幅地质图（M51E010020）
title: 黑龙江1∶50 000大黑山幅、大金山幅、四十里大甸子幅、卡大汗河幅区域地质调查报告
titleType: Other
Creators: name: 张；李;周;宋;周;张;张;王;代;李;高, 海；文龙;世强;华;俊杰;宁;健康;婧;宇;德胜;勇
Publisher: name: 全国地质资料馆
Year: 2018
Subjects: subject: 火山岩;中生代侵入岩;区域构造;区域变质岩

description: 本报告是对黑龙江省1∶50 000大黑山、大金山、四十里大甸子、卡大汗河幅区域地质调查幅区调成果的全面总结。报告对大面积分布的火山岩从地层、岩石、岩石化学、岩相、构造等方面进行了研究、总结，将火山岩划分到组，详细划分了火山岩相及火山机构，依据接触关系、同位素测年数据确定了火山岩地层的时代，对第四系松散地层按地貌单位进行了划分。对区内的侵入岩划分了侵入体，建立了填图单位，从岩石学、岩石化学、同位素测年方面进行了总结，确定本区岩浆侵入活动为早石炭世、晚三叠—早侏罗世、晚侏罗世、早白垩世。总结了该区的变质作用类型及变质特征。对区内的韧、脆性构造进行了研究，建立了区域构造格架。对区域成矿地质背景进行了研究、总结，划分了成矿远景区，发现3处黄铁矿化蚀变点。报告还对区内的遥感影像特征、航磁特征进行了总结，对数据库建库工作进行了简述。报告为今后在该区开展地质矿产调查提供了翔实的基础地质资料。
NPR/PBS NewsHour/Marist Poll: April 2020 Coronavirus
Creators: name: National Public Radio
name: PBS NewsHour
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: President Donald Trump approval on issues (2); Trump vs. your governor better handling of issues (2); good or bad idea to reopen activities without further testing for the coronavirus (COVID-19) (4); let go or reduced employment hours due to coronavirus (1); coronavirus a factor in vote for president (1); Trump vs. Former Vice President Joe Biden on issues (2).
Magnetoelectric effect in the helical state of a superconductor/ferromagnet bilayer
Creators: name: Plastovets, V.
name: Buzdin, A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We study the microscopic mechanism of nucleation of the helical superconducting state maintained by a spin-splitting field and weak Rashba spin-orbit coupling in a 2D superconductor/ferromagnet system and present an exact solution for the Gor'kov equations, which provides a full description of the thermodynamic properties of the system under consideration. This permits us to obtain the Ginzburg-Landau expansion and use it to analyze the possibility of controlling magnetization using the transport supercurrent in both dc and quasistatic ac regimes. We show that these properties are related to the manifestation of the diode effect in superconducting systems with spin-orbit interaction.
Dehesa of Casablanca, Oliva de Plasencia, Cáceres, Spain
Creators: name: Bertomeu, Manuel
Publisher: name: Zenodo
Year: 2021

description: Dehesa of Casablanca is a family owned and managed livestock farm located in Oliva de Plasencia, southwestern Spain. It is a productive, profitable and environmentally friendly organic farm that can be considered the epitome of sustainable land management. The concepts of diversity, in habitats, vegetation types, resources, and livelihoods, and adaptability underpins management approaches and decisions. The farm has a total area of 421 ha of wooded pastures, pasture land, cork oak forest and organic olive orchards. Water resources are abundant throughout the farm. There are 2 man-made lakes, 6 ponds and 1 natural spring and a seasonal brook that runs through the farm. These water bodies are important not only for livestock but also as the habitat for a variety of aquatic birds and amphibians, and as the source of drinking water for many wild animals including deer and wild boar.
Pathology of fore and midgut neuroendocrine tumours
Creators: name: Diaz-Cano, Salvador J.
Publisher: name: figshare
Year: 2012
Subjects: subject: Molecular Biology
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Cancer

description: There is much confusion in both definition and practical issues among pathologists and clinicians alike for neuroendocrine tumours/carcinomas (NETs/NECs). This review focuses the attention on key issues of foregut and midgut NET: pathological features (nomenclature, classification, diagnostic criteria, grading, staging, markers and prognosis), molecular genetics, and how to approach common problems in NET (multifocal vs multicentric, metastatic potential and prediction of primary site). The value of the term neuroendocrine is related to its connotation of a particular phenotype or differentiation pattern. Accordingly, the NET nomenclature can be addressed by using any of the following groups of terms: (1) well-differentiated NET, well-differentiated NEC, or poorly differentiated NEC; or (2) NECs (grades IeIII), indicating in an explanatory note the equivalent terminology, when appropriate. Ultimately, the use of specific NET terms remains a personal preference, but what is the most critical is the necessity that the terms will be understood by health professionals caring for patients and that the terms can be grouped and translated for epidemiologic and molecular studies that can offer unique targets for specific therapies.
Ageleradix schwendingeri Zhang, Li & Xu 2008
Creators: name: Mu, Yan-Nan
name: Wang, Lu-Yu
name: Ren, Tian-Yu
name: Tian, Yuan
name: Zhang, Zhi-Sheng
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Agelenidae
Ageleradix
Ageleradix schwendingeri

description: Ageleradix schwendingeri Zhang, Li & Xu, 2008
Fig. 5
Material examined.
China, Xizang • 2 ♂ 3 ♀, Chayu Co., Xiachayu Town, Xiachayu Bridge, scrub-grassland near river, 28°27'24.72"N, 97°02'40.68"E, elev. 1464 m, 26.06.2018, leg. L. Y. Wang et al. • 1 ♀, Chayu Co., 28°39'35.88"N, 97°27'57.84"E, elev. 2323 m, 25.06.2018, leg. L. Y. Wang. • 1 ♂ 1 ♀, Chayu Co., 28°39'35.88"N, 97°27'57.84"E, elev. 2323 m, 25.05.2019, leg. L. Y. Wang and P. Liu. • 1 ♂, Chayu Co., 28°39'35.88"N, 97°27'57.84"E, elev. 2323 m, 27.05.2019, leg. L. Y. Wang.
Diagnosis and description.
See Zhu et al. (2017).
Distribution.
China (Xizang, Sichuan).
description: Published as part of Mu, Yan-Nan, Wang, Lu-Yu, Ren, Tian-Yu, Tian, Yuan & Zhang, Zhi-Sheng, 2025, Review of the genus Ageleradix Xu & Li, 2007 (Araneae, Agelenidae), with descriptions of three new species, pp. 197-208 in ZooKeys 1236 on pages 197-208, DOI: 10.3897/zookeys.1236.143650
Additional analysis information from Children’s subjective uncertainty-driven sampling behaviour
Creators: name: de Eccher, Martina
name: Mundry, Roger
name: Mani, Nivedita
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 529999
subject: Other psychology not elsewhere classified

description: A detailed description of the analysis, including random effects structure of the models and details about significance tests
The continued accumulation of anthropogenic carbon in the global ocean during the 2010s
Creators: name: Müller, Jens Daniel
name: Zhu, Donghe
name: Gregor, Luke
name: Olsen, Are
name: Lange, Nico
name: Lauvset, Siv
name: Tanhua, Toste
name: Ishii, Masao
name: Perez, Fiz Fernandez
name: Carter, Brendan
name: Feely, Richard
name: Wanninkhof, Rik
name: Gruber, Nicolas
Publisher: name: ETH Zurich
Year: 2021

description: Surface ocean pCO2-based estimates and models indicate that the ocean sink for anthropogenic CO2 (Cant) has continued to increase unabatedly over the past decade. However, the most recent global and observation-based estimate of the accumulation of Cant in the ocean interior by Gruber et al. (2019) does not extend beyond 2007, preventing an independent assessment of this increase in the magnitude of the sink.

Here, we exploit about 50,000 additional observations of dissolved inorganic carbon (DIC) and other relevant biogeochemical parameters, to extend the Gruber et al. analysis based on the eMLR(C*) method to the 2010s. These data were collected from all major ocean basins over the past decade by GO-SHIP and associated programs, and assembled through GLODAPv2.2020 into an internally consistent data product. We refine the eMLR(C*) method in three ways to achieve the updated storage estimates: (1) the uncertainty assessment is improved, based on a coupled analysis of observations and synthetic data generated from an ocean biogeochemical model, (2) the robustness of the multiple linear regression models is increased, using more stringent predictor and model selection procedures, and (3) the mapping of the Cant fields relies on a MLR ensemble approach that takes into account co-occurring temporal changes of the predictor variables salinity, temperature and oxygen.


Initial results show that the ocean has continued to act as a strong Cant sink with an average uptake rate of 2.8 ± 0.3 Pg C yr-1 between the reference years 2007 and 2015. This represents a small increase in rate compared to 2.6 ± 0.3 Pg C yr-1 determined for the 1994 through 2007 period. This increase is slightly smaller than expected on the basis of the growth of atmospheric CO2 over the period, but associated uncertainties are too large to make a conclusive statement about whether the ocean carbon sink is slowing down. Initial analyses of the synthetic data indicate that variable ocean circulation and limited sampling, especially the small number of cruises in the Indian Ocean, represent the biggest sources of uncertainty for the eMLR(C*)-based estimate. However, our preliminary sink estimate is in good agreement with recent air-sea CO2 flux-based uptake estimates, based on an ensemble of surface pCO2 interpolation techniques once these fluxes are adjusted for the river carbon input driven outgassing of natural CO2.
description: EGUsphere
GLP-1 and Glucagon Secretion from a Pancreatic Neuroendocrine Tumor Causing Diabetes and Hyperinsulinemic Hypoglycemia.
Creators: name: Diaz-Cano, Salvador J.
name: S Aylwin
name: B C Whitelaw
name: M Zhao
name: A Quaglia
name: G C Huang
name: J Ramage
name: C W Le Roux
name: R E Roberts
Publisher: name: figshare
Year: 2012
Subjects: subject: Molecular Biology
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Cancer

description: Context: Glucagon-like peptide-1 (GLP-1) is a gut peptide that promotes insulin release from pancreatic β-cells and stimulates β-cell hyperplasia. GLP-1 secretion causing hypoglycemia has been described once from an ovarian neuroendocrine tumor (NET) but has not been reported from a pancreatic NET (pNET). Objective: A 56-yr-old male with a previous diagnosis of diabetes presented with fasting hypoglycemia and was found to have a metastatic pNET secreting glucagon. Neither the primary tumor nor metastases stained for insulin, whereas the resected normal pancreas showed histological evidence of islet cell hyperplasia. We provide evidence that GLP-1 secretion from the tumor was the cause of hyperinsulinemic hypoglycemia. Methods: GLP-1 levels were determined in the patient, and immunohistochemistry for GLP-1 was performed on the tumor metastases. Ex vivo tissue culture and a bioassay constructed by transplantation of tumor into nude mice were performed to examine the tumor secretory products and their effects on islet cell function. Results: The patient had high levels of glucagon and GLP-1 with an exaggerated GLP-1 response to oral glucose. Immunohistochemistry and primary tissue culture demonstrated secretion of glucagon and GLP-1 from the tumor metastases, whereas insulin secretion was almost undetectable. Ex vivo coculture of the tumor with normal human islets resulted in inhibition of insulin release, and transplanted mice developed impaired glucose tolerance. Conclusions: This is the first description of glucagon and GLP-1 secretion from a metastatic pNET causing sequential diabetes and hypoglycemia. Hypoglycemia was caused by insulin secretion from hyperplastic β-cells stimulated by tumor-derived GLP-1.
Krasovsky K (2012) Tobacco taxation policy in three Baltic countries after the EU accession
Creators: name: Andreeva, Tatiana
name: Krasovsky, Konstantin
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Economics

description: Tobacco taxation policy in three Baltic countries after the EU accession
Konstantin Krasovsky BACKGROUND: Estonia, Latvia and Lithuania joined the EU in 2004 and had to increase tobacco excise rates. The aim of the paper is to explore the impact of tax policies on tobacco consumption, revenue and tobacco market in the Baltic countries.
METHODS: Data on tobacco sales, tax rates, prices, revenues, and smoking prevalence were taken from databases and reports. Tobacco affordability index was calculated using data on prices and GDP.
RESULTS: Tobacco taxation policy had three similar stages in Baltic countries: (1) In 2004-2007, tax rates increased slowly and cigarettes became more affordable in years of economic boom. Tobacco consumption and smuggling out of Baltic countries was on the rise, which caused increase of sales and revenues. (2) In 2008-2009, Baltic countries had to hike excise and VAT rates in years of economic recession, which caused sharp decline of cigarette affordability and resulted in large decline of consumption and sales and some excise revenue downfall in 2009-2010; however, all countries had higher revenues in 2010 than in 2007. (3) In 2011, economic situation improved and tobacco sales and revenue increased.
The tobacco taxation policy in Baltic countries in 2004-2011 resulted in: (1) decline of total (licit + illicit) annual cigarette consumption by 30% both in Latvia and Lithuania, and by 10% in Estonia; (2) decline of daily smoking prevalence by 10-20%; (3) decline of the out-of-country smuggling; (4) almost no changes in volumes of smuggling into Lithuania and Estonia; (5) three-fold increase of the annual tobacco revenues in three countries combined.
CONCLUSIONS: Decrease of tobacco affordability caused by tax hikes and economic recession was the key factor of tobacco consumption decline. Tobacco tax hike is a win-win policy, while in years of economic boom it has more fiscal benefits and in years of economic recession it has more public health benefits.

KEYWORDS: tobacco; excise tax; Estonia; Latvia; Lithuania; Baltic countries; affordability; smoking prevalence; tobacco consumption; tobacco smuggling.