cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans
Creators: name: Haiman, Christopher A.
name: Chen, Fang
name: Stram, Daniel O.
name: Chanock, Stephen J.
name: Henderson, Brian E.
name: Deming, Sandra L.
name: Nyante, Sarah
name: Chen, Gary K.
name: Hu, Jennifer J.
name: Bandera, Elisa V.
name: Le Marchand, Loïc
name: Ziegler, Regina G.
name: Rodriguez-Gil, Jorge L.
name: Rebbeck, Timothy R.
name: Palmer, Julie R.
name: Kolonel, Laurence N.
name: John, Esther M.
name: Zheng, Wei
name: Bernstein, Leslie
name: Press, Michael F.
name: Millikan, Robert C.
name: Ingles, Sue A.
name: Ambrosone, Christine B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Genome-wide association studies (GWAS) have revealed 19 common genetic variants that are associated with breast cancer risk. Testing of the index signals found through GWAS and fine-mapping of each locus in diverse populations will be necessary for characterizing the role of these risk regions in contributing to inherited susceptibility. In this large study of breast cancer in African-American women (3016 cases and 2745 controls), we tested the 19 known risk variants identified by GWAS and replicated associations (P < 0.05) with only 4 variants. Through fine-mapping, we identified markers in four regions that better capture the association with breast cancer risk in African Americans as defined by the index signal (2q35, 5q11, 10q26 and 19p13). We also identified statistically significant associations with markers in four separate regions (8q24, 10q22, 11q13 and 16q12) that are independent of the index signals and may represent putative novel risk variants. In aggregate, the more informative markers found in the study enhance the association of these risk regions with breast cancer in African Americans [per allele odds ratio (OR) = 1.18, P = 2.8 × 10−24 versus OR = 1.04, P = 6.1 × 10−5]. In this detailed analysis of the known breast cancer risk loci, we have validated and improved upon markers of risk that better characterize their association with breast cancer in women of African ancestry.
Quantum Fisher information and symmetric logarithmic derivative via anti-commutators
Creators: name: Liu, Jing
name: Chen, Jie
name: Jing, Xiao-Xing
name: Wang, Xiaoguang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Symmetric logarithmic derivative (SLD) is a key quantity to obtain quantum Fisher information (QFI) and to construct the corresponding optimal measurements. Here we develop a method to calculate the SLD and QFI via anti-commutators. This method is originated from the Lyapunov representation and would be very useful for cases that the anti-commutators among the state and its partial derivative exhibits periodic properties. As an application, we discuss a class of states, whose squares linearly depend on the states themselves, and give the corresponding analytical expressions of SLD and QFI. A noisy scenario of this class of states is also considered and discussed. Finally, we readily apply the method to the block-diagonal states and the multi-parameter estimation problems.
description: 12 pages, no figure
Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3
Creators: name: Pan, Yanzhen
name: Bousquet-Moore, Danielle
name: McCoy, Portia A.
name: Beaudet, Arthur L.
name: Kim, Caroline J.
name: Lorenzo, Isabel
name: Ehlers, Michael D.
name: Philpot, Benjamin D.
name: Weinberg, Richard J.
name: Berrios, Janet
name: Wu, Gangyi
name: Wang, Xiaoming
name: Rodriguiz, Ramona M.
name: Colvin, Jennifer S.
name: Jiang, Yong-hui
name: Wetsel, William C.
name: Roberts, Adam C.
name: Je, H. Shawn
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: SHANK3 is a synaptic scaffolding protein enriched in the postsynaptic density (PSD) of excitatory synapses. Small microdeletions and point mutations in SHANK3 have been identified in a small subgroup of individuals with autism spectrum disorder (ASD) and intellectual disability. SHANK3 also plays a key role in the chromosome 22q13.3 microdeletion syndrome (Phelan–McDermid syndrome), which includes ASD and cognitive dysfunction as major clinical features. To evaluate the role of Shank3 in vivo, we disrupted major isoforms of the gene in mice by deleting exons 4–9. Isoform-specific Shank3e4–9 homozygous mutant mice display abnormal social behaviors, communication patterns, repetitive behaviors and learning and memory. Shank3e4–9 male mice display more severe impairments than females in motor coordination. Shank3e4–9 mice have reduced levels of Homer1b/c, GKAP and GluA1 at the PSD, and show attenuated activity-dependent redistribution of GluA1-containing AMPA receptors. Subtle morphological alterations in dendritic spines are also observed. Although synaptic transmission is normal in CA1 hippocampus, long-term potentiation is deficient in Shank3e4–9 mice. We conclude that loss of major Shank3 species produces biochemical, cellular and morphological changes, leading to behavioral abnormalities in mice that bear similarities to human ASD patients with SHANK3 mutations.
การบริหารแรงงานต่างด้าวสัญชาติพม่าโดยผู้ประกอบการคนไทย ในจังหวัดสมุทรสาคร
Creators: name: กันยา ศรีสวัสดิ์
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Labor Management
Burmese Migrant Workers
Samut Sakhon Province

description: Journal of Politics and Governance, 10, 3, 88-119
Drinfeld center and representation theory for monoidal categories
Creators: name: Neshveyev, Sergey
name: Yamashita, Makoto
Publisher: name: arXiv
Year: 2015
Subjects: subject: Operator Algebras (math.OA)
subject: Category Theory (math.CT)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics

description: Motivated by the relation between the Drinfeld double and central property (T) for quantum groups, given a rigid C*-tensor category C and a unitary half-braiding on an ind-object, we construct a *-representation of the fusion algebra of C. This allows us to present an alternative approach to recent results of Popa and Vaes, who defined C*-algebras of monoidal categories and introduced property (T) for them. As an example we analyze categories C of Hilbert bimodules over a II$_1$-factor. We show that in this case the Drinfeld center is monoidally equivalent to a category of Hilbert bimodules over another II$_1$-factor obtained by the Longo-Rehren construction. As an application, we obtain an alternative proof of the result of Popa and Vaes stating that property (T) for the category defined by an extremal finite index subfactor $N \subset M$ is equivalent to Popa's property (T) for the corresponding SE-inclusion of II$_1$-factors. In the last part of the paper we study Müger's notion of weakly monoidally Morita equivalent categories and analyze the behavior of our constructions under the equivalence of the corresponding Drinfeld centers established by Schauenburg. In particular, we prove that property (T) is invariant under weak monoidal Morita equivalence.
description: v3: minor corrections, to appear in Comm. Math. Phys.; v2: 37 pages, with a new section; v1: 24 pages
Geodesics of positive Lagrangians in Milnor fibers
Creators: name: Solomon, Jake P.
name: Yuval, Amitai M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Symplectic Geometry (math.SG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53D12, 53C22 (primary), 58B20, 58J70, 53D38 (secondary)

description: The space of positive Lagrangians in an almost Calabi-Yau manifold is an open set in the space of all Lagrangian submanifolds. A Hamiltonian isotopy class of positive Lagrangians admits a natural Riemannian metric $Υ$, which gives rise to a notion of geodesics. We study geodesics of positive $O_n(\mathbb{R})$ invariant Lagrangian spheres in $n$-dimensional $A_m$ Milnor fibers. We show the existence and uniqueness of smooth solutions to the initial value problem and the boundary value problem. In particular, we obtain examples of smooth geodesics of positive Lagrangians in arbitrary dimension. As an application, we show that the Riemannian metric $Υ$ induces a metric space structure on the space of positive $O_n(\mathbb{R})$ invariant Lagrangian spheres in the above mentioned Milnor fibers.
description: 38 pages; added references and background, improved exposition, fixed minor errors
Contribution of novel ATGL missense mutations to the clinical phenotype of NLSD-M: a strikingly low amount of lipase activity may preserve cardiac function
Creators: name: Missaglia, Sara
name: Pennisi, Elena M.
name: Maiwald, Robert
name: Tavian, Daniela
name: Coleman, Rosalind A.
name: Redaelli, Chiara
name: Arca, Marcello
name: Wessalowski, Ruediger
name: Invernici, Gloria
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The lack of adipose triglyceride lipase (ATGL), a patatin-like phospholipase domain-containing enzyme that hydrolyzes fatty acids from triacylglycerol (TAG) stored in multiple tissues, causes the autosomal recessive disorder neutral lipid storage disease with myopathy (NLSD-M). In two families of Lebanese and Italian origin presenting with NLSD-M, we identified two new missense mutations in highly conserved regions of ATGL (p.Arg221Pro and p.Asn172Lys) and a novel nonsense mutation (p.Trp8X). The Lebanese patients harbor homozygous p.Arg221Pro, whereas the Italian patients are heterozygotes for p.Asn172Lys and the p.Trp8X mutation. The p.Trp8X mutation results in a complete absence of ATGL protein, while the p.Arg221Pro and p.Asn172Lys mutations result in proteins with minimal lipolytic activity. Although these mutations did not affect putative catalytic residues or the lipid droplet (LD)-binding domain of ATGL, cytosolic LDs accumulated in cultured skin fibroblasts from the patients. The missense mutations might destabilize a random coil (p.Asn172Lys) or a helix (p.Arg221Pro) structure within or proximal to the patatin domain of the lipase, thereby interfering with the enzyme activity, while leaving intact the residues required to localize the protein to LDs. Overexpressing wild-type ATGL in one patient's fibroblasts corrected the metabolic defect and effectively reduced the number and area of cellular LDs. Despite the poor lipase activity in vitro, the Lebanese siblings have a mild myopathy and not clinically evident myocardial dysfunction. The patients of Italian origin show a late-onset and slowly progressive skeletal myopathy. These findings suggest that a small amount of correctly localized lipase activity preserves cardiac function in NLSD-M.
การสร้างเครือข่ายป้องกันอาชญากรรมในจังหวัดภูเก็ต
Creators: name: ศักดิ์ชัย แก้วพวง
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Networking, Crime Prevention, Phuket Province

description: Journal of Politics and Governance, 10, 3, 120-138
รูปแบบการพัฒนาคุณภาพชีวิตของผู้สูงอายุเชิงนโยบายสาธารณะ: กรณีศึกษาจังหวัดสุรินทร์
Creators: name: เพียร เป็นพร้อม
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Developing model
Quality of Life
Elderly

description: Journal of Politics and Governance, 10, 3, 139-154
การพัฒนาคุณภาพชีวิตคนพิการในโครงการบริการสังคมของมูลนิธิพระมหาไถ่เพื่อการพัฒนาคนพิการ (บาทหลวงเรย์มอนด์ เอ เบรนนัน)
Creators: name: เกศสุดา อินทร์สาหร่าย
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Quality of Life
Disabled
Social Services

description: Journal of Politics and Governance, 10, 3, 155-176
แนวทางในการพัฒนางานทะเบียนราษฎรของสำนักทะเบียนท้องถิ่น เทศบาลตำบลพรเจริญ อำเภอพรเจริญ จังหวัดบึงกาฬ
Creators: name: จิณห์นิภา แสงแก่นสาร
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Decentralization
Civil Registration
Local Administration

description: Journal of Politics and Governance, 10, 3, 177-189
ความเคลื่อนไหวและพฤติกรรมทางการเมืองของผู้สมัครรับเลือกตั้งสมาชิกผู้แทนราษฎรในจังหวัดกาฬสินธุ์
Creators: name: กตัญญู แก้วหานาม
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Movement
Political Behavior
Candidates for the House of Representatives
Kalasin Province

description: Journal of Politics and Governance, 10, 3, 190-205
The subgroup $PSL(2,R)$ is spherical in the group of diffeomorphisms of the circle
Creators: name: Neretin, Yury A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 22E66, 43A90, 81R10

description: We show that the group $PSL(2,R)$ is a spherical subgroup in the group of $C^3$-diffeomorphisms of the circle. Also, the group of automorphisms of a Bruhat--Tits tree is a spherical subgroup in the group of hierarchomorphisms of the tree.
description: 6pp, typos were corrected
Individual common variants exert weak effects on the risk for autism spectrum disorders
Creators: name: Folstein, Susan E.
name: Crawford, Emily L.
name: Glessner, Joseph T.
name: Gilbert, John
name: Bolshakova, Nadia
name: Gillberg, Christopher
name: Almeida, Joana
name: Fombonne, Eric
name: Anney, Richard
name: Correia, Catarina
name: Brennan, Sean
name: Farrar, Penny
name: Baird, Gillian
name: Bourgeron, Thomas
name: de Jonge, Maretha
name: Conroy, Judith
name: Pinto, Dalila
name: Green, Jonathan
name: Corsello, Christina
name: Guter, Stephen J.
name: Bolton, Patrick F.
name: Casey, Jillian
name: Klei, Lambertus
name: Estes, Annette
name: Fernandez, Bridget A.
name: Delorme, Richard
name: Bacchelli, Elena
name: Brian, Jessica
name: Green, Andrew
name: Duketis, Eftichia
name: Bölte, Sven
name: Duque, Frederico
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: While it is apparent that rare variation can play an important role in the genetic architecture of autism spectrum disorders (ASD), the contribution of common variation to ASD risk is less clear. To produce a more comprehensive picture, we report Stage 2 of the Autism Genome Project genome-wide association study, adding 1301 ASD families and bringing the total to 2705 families analysed (Stages 1 and 2). In addition to evaluating association of individual SNPs, we also sought evidence that common variants, en masse, might affect risk. Despite genotyping over a million SNPs covering the genome, no single SNP shows significant association with ASD or selected phenotypes at a genome-wide level. The SNP that achieves the smallest p-value from secondary analyses is rs1718101. It falls in CNTNAP2, a gene previously implicated in susceptibility for ASD. This SNP also shows modest association with age of word/phrase acquisition in ASD subjects, of interest because features of language development are also associated with other variation in CNTNAP2. By contrast, allele-scores derived from the transmission of common alleles to Stage 1 cases significantly predict case-status in the independent Stage 2 sample. Despite being significant, the variance explained by these allele scores was small (Vm< 1%). Based on results from individual SNPs and their en masse effect on risk, as inferred from the allele-score results, it is reasonable to conclude that common variants affect ASD risk but their individual effects are modest.
การพัฒนาพฤติกรรมคุณธรรมจริยธรรม คณะศึกษาศาสตร์และพัฒนศาสตร์ มหาวิทยาลัยเกษตรศาสตร์
Creators: name: สุมิตร สุวรรณ
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Moral
Ethics
Faculty of Education and Development Sciences
Kasetsart University

description: Journal of Politics and Governance, 10, 3, 206-227
A Study of the Microstructure of Tubifex Species with a Reference to Heavy Metal Pollution
Creators: name: Fleming, Thomas P
Publisher: name: London South Bank University
Year: 1979

description: The microstructure of the somatic and generative tissues of the freshwater tubificid oligochaete, Tubifex tubifex Müller, is reported. Descriptions, for the majority of tissues, are based on ultrastructural studies. The morphological account is supplemented by histochemical analyses of protein, carbohydrate and lipid moieties within selected tissue components. These include the cuticle, the chloragosome granules within chloragogen cells, oocytic yolk granules and the secretory material within the gland cells of the clitellum, atrium, prostrate gland and spermatheca. The order of increasing toxicity of four heavy metals to T. tubifex was iron < zinc < copper < cadmium with 48 hour LC50 values of >10, 9.25, 0.22 and 0.13 mg/l respectively. The accumulation of zinc-65 by the organism was essentially linear throughout 20 days, Uptake of the radioisotope was greater at 5 mg/1 Zn than at 1 mg/1 Zn but was suppressed by the presence of an antibiotic. The cytochemical location of specific and non-specific heavy metals occurred within chloragosomes, cuticle, chaetal sacs and, to a lesser extent, intestine, epidermis and blood plasma. Ultrastructural sites of heavy metals were principally within areas of low metabolic activity. The somatic tissue most sensitive to zinc-induced pathology was the body wall musculature followed by the epidermis, intestine and chloragogen tissues. The fine structural degenerative changes within these tissues following zinc pollution are described and equated with those resulting from non-chemical stress (heated medium). Cytolocation of zinc occurred within the lumen of nephridia following incubation in zinc-rich medium.
Error-in-Variables Jump Regression Using Local Clustering
Creators: name: Kang, Yicheng
name: Gong, Xiaodong
name: Gao, Jiti
name: Qiu, Peihua
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: Error-in-variables regression is widely used in econometric models. The statistical analysis becomes challenging when the regression function is discontinuous and
การใช้ระบบการจัดการเอกสารอิเล็กทรอนิกส์ (EDS) ของบุคลากรวิทยาลัยการเมืองการปกครอง มหาวิทยาลัยมหาสารคาม
Creators: name: ธราภร อนุเวช
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: The use of Electronic Document System
Problems and obstacles in Using
College of Politics and Governance

description: Journal of Politics and Governance, 10, 3, 228-241
Preferential sampling and small-scale clustering of gyrotactic microswimmers in turbulence
Creators: name: Gustavsson, K.
name: Berglund, F.
name: Jonsson, P. R.
name: Mehlig, B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: Recent studies show that spherical motile micro-organisms in turbulence subject to gravitational torques gather in down-welling regions of the turbulent flow. By analysing a statistical model we analytically compute how shape affects the dynamics, preferential sampling, and small-scale spatial clustering. We find that oblong organisms may spend more time in up-welling regions of the flow, and that all organisms are biased to regions of positive fluid-velocity gradients in the upward direction. We analyse small-scale spatial clustering and find that oblong particles may either cluster more or less than spherical ones, depending on the strength of the gravitational torques.
description: 5 pages, 2 figures, supplemental material, as published
MOESM1 of Acupuncture treatment on the motor area of the scalp for motor dysfunction in children with cerebral palsy: study protocol for a multicenter randomized controlled trial
Creators: name: Wang, Jun
name: Shi, Wei
name: Dhiaedin Khiati
name: Bingpei Shi
name: Xiaojuan Shi
name: Dandan Luo
name: Wang, Yin
name: Rencai Deng
name: Huayu Huang
name: Li, Jian
name: Weili Yan
name: Yang, Hong
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1. SPIRIT checklist.
Specification Testing for Nonlinear Multivariate Cointegrating Regressions
Creators: name: Dong, Chaohua
name: Gao, Jiti
name: Tjostheim, Dag
name: Yin, Jiying
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: This paper considers a general model specification test for nonlinear multivariate cointegrating regressions where the regressor consists of a univariate
Population-specific coding variant underlies genome-wide association with adiponectin level
Creators: name: Lange, Ethan M.
name: Lange, Leslie A.
name: Wu, Ying
name: Combs, Terry P.
name: Croteau-Chonka, Damien C.
name: Fogarty, Marie P.
name: Mohlke, Karen L.
name: Kuzawa, Christopher W.
name: Adair, Linda S.
name: AbdelBaky, Omar
name: Luo, Jingchun
name: Borja, Judith B.
name: McDade, Thomas W.
name: Li, Yun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Adiponectin is a protein hormone that can affect major metabolic processes including glucose regulation and fat metabolism. Our previous genome-wide association (GWA) study of circulating plasma adiponectin levels in Filipino women from the Cebu Longitudinal Health and Nutrition Survey (CLHNS) detected a 100 kb two-SNP haplotype at KNG1–ADIPOQ associated with reduced adiponectin (frequency = 0.050, P = 1.8 × 10−25). Subsequent genotyping of CLHNS young adult offspring detected an uncommon variant [minor allele frequency (MAF) = 0.025] located ∼800 kb from ADIPOQ that showed strong association with lower adiponectin levels (P = 2.7 × 10−15, n = 1695) and tagged a subset of KNG1–ADIPOQ haplotype carriers with even lower adiponectin levels. Sequencing of the ADIPOQ-coding region detected variant R221S (MAF = 0.015, P = 2.9 × 10−69), which explained 17.1% of the variance in adiponectin levels and largely accounted for the initial GWA signal in Filipinos. R221S was not present in 12 514 Europeans with previously sequenced exons. To explore the mechanism of this substitution, we re-measured adiponectin level in 20 R221S offspring carriers and 20 non-carriers using two alternative antibodies and determined that the presence of R221S resulted in artificially low quantification of adiponectin level using the original immunoassay. These data provide an example of an uncommon variant responsible for a GWA signal and demonstrate that genetic associations with phenotypes measured by antibody-based quantification methods can be affected by uncommon coding SNPs residing in the antibody target region.
ความต้องการในการพัฒนาตนเองของบุคลากรสายวิชาการ วิทยาลัยการเมืองการปกครอง มหาวิทยาลัยมหาสารคาม
Creators: name: อุษณี สืบพันธุ์โพธิ์
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Self-Improvement
Academic Staffs
Lecturer

description: Journal of Politics and Governance, 10, 3, 242-257
Direct solution to constrained tropical optimization problems with application to project scheduling
Creators: name: Krivulin, N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: Systems and Control (eess.SY)
subject: FOS: Mathematics
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 65K10 (Primary), 15A80, 65K05, 90C48, 90B35 (Secondary)

description: We examine a new optimization problem formulated in the tropical mathematics setting as a further extension of certain known problems. The problem is to minimize a nonlinear objective function, which is defined on vectors over an idempotent semifield by using multiplicative conjugate transposition, subject to inequality constraints. As compared to the known problems, the new one has a more general objective function and additional constraints. We provide a complete solution in an explicit form to the problem by using an approach that introduces an auxiliary variable to represent the values of the objective function, and then reduces the initial problem to a parametrized vector inequality. The minimum of the objective function is evaluated by applying the existence conditions for the solution of this inequality. A complete solution to the problem is given by solving the parametrized inequality, provided the parameter is set to the minimum value. As a consequence, we obtain solutions to new special cases of the general problem. To illustrate the application of the results, we solve a real-world problem drawn from time-constrained project scheduling, and offer a representative numerical example.
Integral powers of numbers in small intervals modulo $1$: The cardinality gap phenomenon
Creators: name: Schleischitz, Johannes
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11B05, 11J71, 11K16, 11K31

description: This paper deals with the distribution of $αζ^{n} \bmod 1$, where $α\neq 0,ζ>1$ are fixed real numbers and $n$ runs through the positive integers. Denote by $\Vert.\Vert$ the distance to the nearest integer. We investigate the case of $αζ^{n}$ all lying in prescribed small intervals modulo $1$ for all large $n$, with focus on the case $\Vertαζ^{n}\Vert \leq ε$ for small $ε>0$. We are particularly interested in what we call cardinality gap phenomena. For example for fixed $ζ>1$ and small $ε>0$ there are at most countably many values of $α$ such that $\Vertαζ^{n}\Vert \leq ε$ for all large $n$, whereas larger $ε$ induces an uncountable set. We investigate the value of $ε$ at which the gap occurs. We will pay particular attention to the case of algebraic and, more specific, rational $ζ>1$. Results concerning Pisot and Salem numbers such as some contribution to Mahler's $3/2$-problem are implicitly deduced. We study similar questions for fixed $α\neq 0$ as well.
description: 17 pages. A. Dubickas thankfully pointed out to me that the initial version of Theorem 2.1 can be improved by a result of Dobrowolski
Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study
Creators: name: North, Kari E.
name: Chen, Zhao
name: Brzyski, Robert G.
name: Kooperberg, Charles
name: Carlson, Christopher S.
name: Chen, Christina T. L.
name: Rajkovic, Aleksandar
name: Fernández-Rhodes, Lindsay
name: Franceschini, Nora
name: Heiss, Gerardo
name: Woods, Nancy F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Several genome-wide studies have identified loci associated with reproductive traits, such as ages of menarche and menopause, in women of European ancestry. In this study, we investigated the relevance of these loci in minority US Hispanic women. We utilized data from 3468 women who were genotyped as a part of the Women's Health Initiative SNP Health Association Resource. We replicated associations of eight loci (LRP18, LIN28B, CENPW, INHBA, TMEM38B, ZNF483, NFAT5 and OLFM2) with age at menarche, and of two loci (MCM8 and BRSK1/TMEM150B) with age at menopause. The MCM8 locus was also associated with early menopause risk. Three loci (CENPW, MCM8 and BRSK1/TMEM150B) were associated with the length of reproductive lifespan. We provide evidence that genetic variants influencing reproductive traits identified in European populations are also important in minority US Hispanic women.
เปลื้องปก: การเมืองเรื่องของปกแบบเรียนหน้าที่พลเมืองทศวรรษ 2550
Creators: name: ณัทธนัทธ์ เลี่ยวไพโรจน์
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Textbook’s cover
Thai Civics
Nation, Religion, Monarchy
Democracy

description: Journal of Politics and Governance, 10, 3, 258-287
Evaluation am ZMS
Creators: name: Alf, Tobias
Publisher: name: Zenodo
Year: 2023
Subjects: Evaluation
Planspiel

description: Am ZMS werden Planspiele evaluiert. Dieser Artikel gibt einen Überblick über erste Ergebnisse und geht insbesondere auf Erwartungen und die Gesamtbeurteilung der Studierenden ein.
Q Data Insight: "Educators' receiving and sharing research and evidence"
Creators: name: Gleeson, Jo
name: Rickinson, Mark
name: Walsh, Lucas
name: Khong, Hang
name: Plant, Bernice
name: Cutler, Blake
name: Boulet, Mark
name: Hall, Genevieve
name: Salisbury, Mandy
Publisher: name: Monash University
Year: 2022
Subjects: Teacher education and professional development of educators
Educational administration, management and leadership
Other education not elsewhere classified

description: Monash Q Project's Q Data Insights provide a summary of key findings from project research activities. This Data Insight showcases draws on data from a Monash Q Project survey with 819 Australian educators. It focused on the theme of 'receiving and sharing research and evidence.'
การบริการสาธารณะด้านการจัดการศึกษาขององค์กรปกครองส่วนท้องถิ่น ภายใต้บริบทการกระจายอำนาจในรอบสองทศวรรษ
Creators: name: สุเชาวน์ มีหนองหว้า
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2020
Subjects: Public Service
Decentralization
Educational Public Service

description: Journal of Politics and Governance, 10, 3, 288-302
Inequivalence of entanglement, steering, and Bell nonlocality for general measurements
Creators: name: Quintino, Marco Túlio
name: Vértesi, Tamás
name: Cavalcanti, Daniel
name: Augusiak, Remigiusz
name: Demianowicz, Maciej
name: Acín, Antonio
name: Brunner, Nicolas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Einstein-Podolsky-Rosen steering is a form of inseparability in quantum theory commonly acknowledged to be intermediate between entanglement and Bell nonlocality. However, this statement has so far only been proven for a restricted class of measurements, namely projective measurements. Here we prove that entanglement, one-way steering, two-way steering and nonlocality are genuinely different considering general measurements, i.e. single round positive-operator-valued-measures. Finally, we show that the use of sequences of measurements is relevant for steering tests, as they can be used to reveal "hidden steering".
description: Typo in equation 13 corrected (noticed by Jessica Bavaresco)
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice
Creators: name: Ou, Yimiao
name: Spreeuw, Amanda
name: Franciosi, Sonia
name: Wong, Bibiana K.Y.
name: Howland, David
name: Xie, Yuanyun
name: Feinberg, Konstantin
name: Cusack, Corey L.
name: Miller, Freda D.
name: Vaid, Kuljeet
name: Deng, Yu
name: Ehrnhoefer, Dagmar E.
name: Skotte, Niels H.
name: Graham, Rona K.
name: Ouyang, Yingbin
name: Zhang, Weining
name: Uribe, Valeria
name: Deshmukh, Mohanish
name: Pouladi, Mahmoud A.
name: Bissada, Nagat
name: Hayden, Michael R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Apoptosis, or programmed cell death, is a cellular pathway involved in normal cell turnover, developmental tissue remodeling, embryonic development, cellular homeostasis maintenance and chemical-induced cell death. Caspases are a family of intracellular proteases that play a key role in apoptosis. Aberrant activation of caspases has been implicated in human diseases. In particular, numerous findings implicate Caspase-6 (Casp6) in neurodegenerative diseases, including Alzheimer disease (AD) and Huntington disease (HD), highlighting the need for a deeper understanding of Casp6 biology and its role in brain development. The use of targeted caspase-deficient mice has been instrumental for studying the involvement of caspases in apoptosis. The goal of this study was to perform an in-depth neuroanatomical and behavioral characterization of constitutive Casp6-deficient (Casp6−/−) mice in order to understand the physiological function of Casp6 in brain development, structure and function. We demonstrate that Casp6−/− neurons are protected against excitotoxicity, nerve growth factor deprivation and myelin-induced axonal degeneration. Furthermore, Casp6-deficient mice show an age-dependent increase in cortical and striatal volume. In addition, these mice show a hypoactive phenotype and display learning deficits. The age-dependent behavioral and region-specific neuroanatomical changes observed in the Casp6−/− mice suggest that Casp6 deficiency has a more pronounced effect in brain regions that are involved in neurodegenerative diseases, such as the striatum in HD and the cortex in AD.
Transmission stability and Raman-induced amplitude dynamics in multichannel soliton-based optical waveguide systems
Creators: name: Peleg, Avner
name: Nguyen, Quan M.
name: Tran, Thinh P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We study transmission stability and dynamics of pulse amplitudes in $N$-channel soliton-based optical waveguide systems, taking into account second-order dispersion, Kerr nonlinearity, delayed Raman response, and frequency dependent linear gain-loss. We carry out numerical simulations with systems of $N$ coupled nonlinear Schrödinger (NLS) equations and compare the results with the predictions of a simplified predator-prey model for Raman-induced amplitude dynamics. Coupled-NLS simulations for single-fiber transmission with $2 \le N \le 4$ frequency channels show stable oscillatory dynamics of soliton amplitudes at short-to-intermediate distances, in excellent agreement with the predator-prey model's predictions. However, at larger distances, we observe transmission destabilization due to resonant formation of radiative sidebands, which is caused by Kerr nonlinearity. The presence of linear gain-loss in a single fiber leads to a limited increase in transmission stability. Significantly stronger enhancement of transmission stability is achieved in a nonlinear $N$-waveguide coupler due to efficient suppression of radiative sideband generation by the linear gain-loss. As a result, the distances along which stable Raman-induced dynamics of soliton amplitudes is observed are significantly larger in the waveguide coupler system compared with the single-fiber system.
description: 47 pages, 12 figures
Validated SNPs for eGFR and their associations with albuminuria
Creators: name: Bochud, M.
name: Fox, C. S.
name: Foster, M. C.
name: Chen, M.-H.
name: Larson, M. G.
name: Ellis, J. W.
name: de Boer, I.
name: Boger, C. A.
name: Kao, L.
name: Kottgen, A.
name: Liu, C.-T.
name: O'Seaghdha, C. M.
name: Parsa, A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Albuminuria and reduced glomerular filtration rate are manifestations of chronic kidney disease (CKD) that predict end-stage renal disease, acute kidney injury, cardiovascular disease and death. We hypothesized that SNPs identified in association with the estimated glomerular filtration rate (eGFR) would also be associated with albuminuria. Within the CKDGen Consortium cohort (n= 31 580, European ancestry), we tested 16 eGFR-associated SNPs for association with the urinary albumin-to-creatinine ratio (UACR) and albuminuria [UACR >25 mg/g (women); 17 mg/g (men)]. In parallel, within the CARe Renal Consortium (n= 5569, African ancestry), we tested seven eGFR-associated SNPs for association with the UACR. We used a Bonferroni-corrected P-value of 0.003 (0.05/16) in CKDGen and 0.007 (0.05/7) in CARe. We also assessed whether the 16 eGFR SNPs were associated with the UACR in aggregate using a beta-weighted genotype score. In the CKDGen Consortium, the minor A allele of rs17319721 in the SHROOM3 gene, known to be associated with a lower eGFR, was associated with lower ln(UACR) levels (beta = −0.034, P-value = 0.0002). No additional eGFR-associated SNPs met the Bonferroni-corrected P-value threshold of 0.003 for either UACR or albuminuria. In the CARe Renal Consortium, there were no associations between SNPs and UACR with a P< 0.007. Although we found the genotype score to be associated with albuminuria (P= 0.0006), this result was driven almost entirely by the known SHROOM3 variant, rs17319721. Removal of rs17319721 resulted in a P-value 0.03, indicating a weak residual aggregate signal. No alleles, previously demonstrated to be associated with a lower eGFR, were associated with the UACR or albuminuria, suggesting that there may be distinct genetic components for these traits.
22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development
Creators: name: Paronett, E. M.
name: Newbern, J. M.
name: Gopalakrishna, D.
name: Meechan, D. W.
name: Maynard, T. M.
name: LaMantia, A.-S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: We asked whether key morphogenetic signaling pathways interact with 22q11 gene dosage to modulate the severity of cranial or cardiac anomalies in DiGeorge/22q1 deletion syndrome (22q11DS). Sonic hedgehog (Shh) and retinoic acid (RA) signaling is altered in the brain and heart—clinically significant 22q11DS phenotypic sites—in LgDel mouse embryos, an established 22q11DS model. LgDel embryos treated with cyclopamine, an Shh inhibitor, or carrying mutations in Gli3Xtj, an Shh-signaling effector, have morphogenetic anomalies that are either not seen, or seen at significantly lower frequencies in control or single-mutant embryos. Similarly, RA exposure or genetic loss of RA function via heterozygous mutation of the RA synthetic enzyme Raldh2 induces novel cranial anomalies and enhances cardiovascular phenotypes in LgDel but not other genotypes. These changes are not seen in heterozygous Tbx1 mutant embryos—a 22q11 gene thought to explain much of 22q11DS pathogenesis—in which Shh or RA signaling has been similarly modified. Our results suggest that full dosage of 22q11 genes beyond Tbx1 establish an adaptive range for morphogenetic signaling via Shh and RA. When this adaptive range is constricted by diminished dosage of 22q11 genes, embryos are sensitized to otherwise benign changes in Shh and RA signaling. Such sensitization, in the face of environmental or genetic factors that modify Shh or RA signaling, may explain variability in 22q11DS morphogenetic phenotypes.
A genome-wide association study of early menopause and the combined impact of identified variants
Creators: name: Chasman, Daniel I.
name: Laven, Joop S. E.
name: Arnold, Alice
name: Launer, Lenore
name: Cornelis, Marilyn C.
name: Zhuang, Wei V.
name: Vernon Smith, Albert
name: Kraft, Peter
name: Goodarzi, Mark O.
name: Chen, Constance
name: Gudnason, Vilmundur
name: Corre, Tanguy
name: Stolk, Lisette
name: Harris, Tamara
name: He, Chunyan
name: Jones, Michael
name: Sulem, Patrick
name: Mangino, Massimo
name: Fischer, Krista
name: Couper, David J.
name: Franceschini, Nora
name: Perry, John R. B.
name: Ashworth, Alan
name: Esko, Tõnu
name: Bergmann, Sven
name: Kutalik, Zoltan
name: Burri, Andrea
name: Rose, Lynda M.
name: Hofman, Albert
name: Weedon, Michael N.
name: Li, Guo
name: Buring, Julie E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Early menopause (EM) affects up to 10% of the female population, reducing reproductive lifespan considerably. Currently, it constitutes the leading cause of infertility in the western world, affecting mainly those women who postpone their first pregnancy beyond the age of 30 years. The genetic aetiology of EM is largely unknown in the majority of cases. We have undertaken a meta-analysis of genome-wide association studies (GWASs) in 3493 EM cases and 13 598 controls from 10 independent studies. No novel genetic variants were discovered, but the 17 variants previously associated with normal age at natural menopause as a quantitative trait (QT) were also associated with EM and primary ovarian insufficiency (POI). Thus, EM has a genetic aetiology which overlaps variation in normal age at menopause and is at least partly explained by the additive effects of the same polygenic variants. The combined effect of the common variants captured by the single nucleotide polymorphism arrays was estimated to account for ∼30% of the variance in EM. The association between the combined 17 variants and the risk of EM was greater than the best validated non-genetic risk factor, smoking.
Extension of the past lifetime and its connection to the cumulative entropy
Creators: name: Di Crescenzo, Antonio
name: Toomaj, Abdolsaeed
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60E15, 62B10, 62N05, 94A17

description: Given two absolutely continuous nonnegative independent random variables, we define the reversed relevation transform as dual to the relevation transform. We first apply such transforms to the lifetimes of the components of parallel and series systems under suitably proportionality assumptions on the hazards rates. Furthermore, we prove that the (reversed) relevation transform is commutative if and only if the proportional (reversed) hazard rate model holds. By repeated application of the reversed relevation transform we construct a decreasing sequence of random variables which leads to new weighted probability densities. We obtain various relations involving ageing notions and stochastic orders. We also exploit the connection of such a sequence to the cumulative entropy and to an operator that is dual to the Dickson-Hipp operator. Iterative formulae for computing the mean and the cumulative entropy of the random variables of the sequence are finally investigated.
Exploring the genetic basis of chronic periodontitis: a genome-wide association study
Creators: name: Beck, J. D.
name: Monda, K. L.
name: Reynolds, L. M.
name: North, K. E.
name: Hsueh, W.-C.
name: Olshan, A. F.
name: Divaris, K.
name: Weyant, R. J.
name: Lange, E. M.
name: Moss, K.
name: Offenbacher, S.
name: Liu, Y.
name: Newman, A. B.
name: Barros, S. P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Chronic periodontitis (CP) is a common oral disease that confers substantial systemic inflammatory and microbial burden and is a major cause of tooth loss. Here, we present the results of a genome-wide association study of CP that was carried out in a cohort of 4504 European Americans (EA) participating in the Atherosclerosis Risk in Communities (ARIC) Study (mean age—62 years, moderate CP—43% and severe CP—17%). We detected no genome-wide significant association signals for CP; however, we found suggestive evidence of association (P < 5 × 10−6) for six loci, including NIN, NPY, WNT5A for severe CP and NCR2, EMR1, 10p15 for moderate CP. Three of these loci had concordant effect size and direction in an independent sample of 656 adult EA participants of the Health, Aging, and Body Composition (Health ABC) Study. Meta-analysis pooled estimates were severe CP (n = 958 versus health: n = 1909)—NPY, rs2521634 [G]: odds ratio [OR = 1.49 (95% confidence interval (CI = 1.28–1.73, P = 3.5 × 10−7))]; moderate CP (n = 2293)—NCR2, rs7762544 [G]: OR = 1.40 (95% CI = 1.24–1.59, P = 7.5 × 10−8), EMR1, rs3826782 [A]: OR = 2.01 (95% CI = 1.52–2.65, P = 8.2 × 10−7). Canonical pathway analysis indicated significant enrichment of nervous system signaling, cellular immune response and cytokine signaling pathways. A significant interaction of NUAK1 (rs11112872, interaction P = 2.9 × 10−9) with smoking in ARIC was not replicated in Health ABC, although estimates of heritable variance in severe CP explained by all single nucleotide polymorphisms increased from 18 to 52% with the inclusion of a genome-wide interaction term with smoking. These genome-wide association results provide information on multiple candidate regions and pathways for interrogation in future genetic studies of CP.
A generalization of manifolds with corners
Creators: name: Joyce, Dominic
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: In conventional Differential Geometry one studies manifolds, locally modelled on ${\mathbb R}^n$, manifolds with boundary, locally modelled on $[0,\infty)\times{\mathbb R}^{n-1}$, and manifolds with corners, locally modelled on $[0,\infty)^k\times{\mathbb R}^{n-k}$. They form categories ${\bf Man}\subset{\bf Man^b}\subset{\bf Man^c}$. Manifolds with corners $X$ have boundaries $\partial X$, also manifolds with corners, with $\mathop{\rm dim}\partial X=\mathop{\rm dim} X-1$. We introduce a new notion of 'manifolds with generalized corners', or 'manifolds with g-corners', extending manifolds with corners, which form a category $\bf Man^{gc}$ with ${\bf Man}\subset{\bf Man^b}\subset{\bf Man^c}\subset{\bf Man^{gc}}$. Manifolds with g-corners are locally modelled on $X_P=\mathop{\rm Hom}_{\bf Mon}(P,[0,\infty))$ for $P$ a weakly toric monoid, where $X_P\cong[0,\infty)^k\times{\mathbb R}^{n-k}$ for $P={\mathbb N}^k\times{\mathbb Z}^{n-k}$. Most differential geometry of manifolds with corners extends nicely to manifolds with g-corners, including well-behaved boundaries $\partial X$. In some ways manifolds with g-corners have better properties than manifolds with corners; in particular, transverse fibre products in $\bf Man^{gc}$ exist under much weaker conditions than in $\bf Man^c$. This paper was motivated by future applications in symplectic geometry, in which some moduli spaces of $J$-holomorphic curves can be manifolds or Kuranishi spaces with g-corners (see the author arXiv:1409.6908) rather than ordinary corners. Our manifolds with g-corners are related to the 'interior binomial varieties' of Kottke and Melrose in arXiv:1107.3320 (see also Kottke arXiv:1509.03874), and to the 'positive log differentiable spaces' of Gillam and Molcho in arXiv:1507.06752.
description: 97 pages, LaTeX. (v3) final version, to appear in Advances in Mathematics
Supplementary document for Ultrafast pulse propagation in graphene-comprising nanophotonic waveguides considering non-perturbative electrodynamic nonlinearity - 6027722.pdf
Creators: name: Pitilakis, Alexandros
name: Kriezis, Emmanouil
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Document with supporting information (derivations, useful formulas, extra results)
title: Wissenschaftliche Arbeitsgruppen und Lehrkultur
Creators: name: Hawelka, Birgit
Publisher: name: Zentrum für Hochschul- und Wissenschaftsdidaktik, Universität Regensburg
Year: 2023

description: Mari Murtonen spricht über ihre aktuellen Forschungsergebnisse zur Bedeutung von Kollaboration in Arbeitsgruppen zur Förderung didaktischer Kompetenzen.